Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P17_F_K19
(692 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_P40925 Cluster: Malate dehydrogenase, cytoplasmic; n=12... 272 4e-72
UniRef50_Q01JC3 Cluster: Malate dehydrogenase; n=8; cellular org... 244 2e-63
UniRef50_A0C8S6 Cluster: Malate dehydrogenase; n=3; Paramecium t... 244 2e-63
UniRef50_Q9UAV5 Cluster: Malate dehydrogenase; n=15; Eukaryota|R... 243 3e-63
UniRef50_A1W9K7 Cluster: Malate dehydrogenase; n=95; cellular or... 231 1e-59
UniRef50_Q23CW4 Cluster: Malate dehydrogenase, cytoplasmic, puta... 230 3e-59
UniRef50_Q2J7E7 Cluster: Malate dehydrogenase; n=24; Bacteria|Re... 219 7e-56
UniRef50_P61973 Cluster: Malate dehydrogenase; n=43; Bacteria|Re... 210 2e-53
UniRef50_A0BHM8 Cluster: Malate dehydrogenase; n=3; Paramecium t... 192 9e-48
UniRef50_Q8I8I5 Cluster: Malate dehydrogenase; n=2; Eukaryota|Re... 190 4e-47
UniRef50_Q4Q7X6 Cluster: Cytosolic malate dehydrogenase, putativ... 187 3e-46
UniRef50_Q4D123 Cluster: Malate dehydrogenase; n=9; Eukaryota|Re... 180 2e-44
UniRef50_Q86S08 Cluster: NAD-specific malate dehydrogenase 1; n=... 179 5e-44
UniRef50_Q9GPV2 Cluster: Cytosolic malate dehydrogenase; n=4; Tr... 177 2e-43
UniRef50_A0D8T3 Cluster: Malate dehydrogenase; n=2; Paramecium t... 177 3e-43
UniRef50_Q9Z6N1 Cluster: Malate dehydrogenase; n=8; Chlamydiacea... 168 1e-40
UniRef50_P15719 Cluster: Malate dehydrogenase [NADP], chloroplas... 163 3e-39
UniRef50_UPI000065DBFD Cluster: Malate dehydrogenase, cytoplasmi... 154 2e-36
UniRef50_A7RRY2 Cluster: Predicted protein; n=1; Nematostella ve... 148 1e-34
UniRef50_Q86S07 Cluster: NAD-specific malate dehydrogenase 2; n=... 145 1e-33
UniRef50_Q7QQW5 Cluster: Malate dehydrogenase; n=2; Giardia inte... 144 1e-33
UniRef50_A2G340 Cluster: Malate dehydrogenase; n=18; Trichomonad... 143 4e-33
UniRef50_Q9GSY3 Cluster: Malate dehydrogenase; n=1; Hypotrichomo... 140 2e-32
UniRef50_Q2SKL3 Cluster: Malate dehydrogenase; n=1; Hahella chej... 139 5e-32
UniRef50_A2E124 Cluster: Malate dehydrogenase; n=6; Trichomonadi... 138 9e-32
UniRef50_Q8T773 Cluster: Putative uncharacterized protein; n=1; ... 122 1e-26
UniRef50_Q08BZ4 Cluster: Zgc:153922; n=4; Danio rerio|Rep: Zgc:1... 109 6e-23
UniRef50_UPI00015B5AB4 Cluster: PREDICTED: similar to CG5362-PA;... 106 6e-22
UniRef50_UPI0000E467CF Cluster: PREDICTED: hypothetical protein;... 104 2e-21
UniRef50_UPI000065D9FE Cluster: malate dehydrogenase 1B, NAD (so... 88 2e-16
UniRef50_Q5I0G3 Cluster: Malate dehydrogenase 1B; n=21; Amniota|... 81 3e-14
UniRef50_UPI0000F2DF6E Cluster: PREDICTED: similar to Malate deh... 69 8e-11
UniRef50_Q53TK9 Cluster: Malate dehydrogenase; n=3; Eutheria|Rep... 52 2e-05
UniRef50_UPI0000DB7CA5 Cluster: PREDICTED: similar to tetratrico... 48 2e-04
UniRef50_A7I5J9 Cluster: L-lactate dehydrogenase precursor; n=1;... 44 0.005
UniRef50_A2SSY4 Cluster: L-lactate dehydrogenase; n=3; Methanomi... 44 0.005
UniRef50_Q2S4R2 Cluster: L-lactate dehydrogenase; n=1; Salinibac... 44 0.005
UniRef50_A1U9V0 Cluster: Lactate/malate dehydrogenase; n=6; Acti... 43 0.006
UniRef50_Q7UY63 Cluster: L-lactate/malate dehydrogenase; n=2; Pl... 40 0.058
UniRef50_Q5CVB2 Cluster: DHHC family palmitoyl transferase with ... 35 2.2
UniRef50_UPI00006D0DE8 Cluster: Latrophilin/CL-1-like GPS domain... 34 2.9
UniRef50_Q8I8U4 Cluster: Lactate dehydrogenase; n=3; Eimeriorina... 34 2.9
UniRef50_A0BUG0 Cluster: Chromosome undetermined scaffold_129, w... 34 3.8
UniRef50_Q1ZR52 Cluster: Beta-lactamase; n=2; Vibrionaceae|Rep: ... 33 5.0
UniRef50_Q0RYH4 Cluster: Putative uncharacterized protein; n=1; ... 33 5.0
UniRef50_Q0U265 Cluster: Putative uncharacterized protein; n=1; ... 33 6.6
UniRef50_A4QXM2 Cluster: Putative uncharacterized protein; n=1; ... 33 6.6
UniRef50_O26290 Cluster: Malate dehydrogenase; n=2; Methanobacte... 33 6.6
UniRef50_Q7NG49 Cluster: L-lactate dehydrogenase; n=4; Cyanobact... 33 6.6
UniRef50_Q2SQM3 Cluster: Putative uncharacterized protein; n=1; ... 33 8.8
UniRef50_Q54DK4 Cluster: Putative uncharacterized protein ak1; n... 33 8.8
>UniRef50_P40925 Cluster: Malate dehydrogenase, cytoplasmic; n=124;
cellular organisms|Rep: Malate dehydrogenase,
cytoplasmic - Homo sapiens (Human)
Length = 334
Score = 272 bits (668), Expect = 4e-72
Identities = 133/227 (58%), Positives = 162/227 (71%), Gaps = 2/227 (0%)
Frame = +3
Query: 15 LLAANVRIFKEQGQALDKAARKDVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLDQ 194
LL ANV+IFK QG ALDK A+K VKV+VVGNPANTN L SK APSIPKENF+ +TRLD
Sbjct: 101 LLKANVKIFKSQGAALDKYAKKSVKVIVVGNPANTNCLTASKSAPSIPKENFSCLTRLDH 160
Query: 195 NRAQSQLAAKIGVPVKDVKRVIIWGNHSSTQFPDASNAVAIVGGAQKSVSEIINDDAYLK 374
NRA++Q+A K+GV DVK VIIWGNHSSTQ+PD ++A + G + V E + DD++LK
Sbjct: 161 NRAKAQIALKLGVTANDVKNVIIWGNHSSTQYPDVNHAKVKLQGKEVGVYEALKDDSWLK 220
Query: 375 GAFVTTVQKRGAAVIXXXXXXXXXXXXXXXXDHMRD-WFLGTEDRWVSMGVVSDG-SYGT 548
G FVTTVQ+RGAAVI DH+RD WF E +VSMGV+SDG SYG
Sbjct: 221 GEFVTTVQQRGAAVIKARKLSSAMSAAKAICDHVRDIWFGTPEGEFVSMGVISDGNSYGV 280
Query: 549 PRDVVYSFPVTVTNGKWKIVEGLTISDFARQMLDATGKELVEXKQEA 689
P D++YSFPV + N WK VEGL I+DF+R+ +D T KEL E K+ A
Sbjct: 281 PDDLLYSFPVVIKNKTWKFVEGLPINDFSREKMDLTAKELTEEKESA 327
>UniRef50_Q01JC3 Cluster: Malate dehydrogenase; n=8; cellular
organisms|Rep: Malate dehydrogenase - Oryza sativa
(Rice)
Length = 352
Score = 244 bits (596), Expect = 2e-63
Identities = 118/226 (52%), Positives = 147/226 (65%), Gaps = 1/226 (0%)
Frame = +3
Query: 15 LLAANVRIFKEQGQALDKAARKDVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLDQ 194
L++ NV I+K Q AL + A + KVLVV NPANTNAL+ ++AP+IP +N T +TRLD
Sbjct: 123 LISKNVTIYKSQASALQQHAAPNCKVLVVANPANTNALVLKEFAPAIPAKNITCLTRLDH 182
Query: 195 NRAQSQLAAKIGVPVKDVKRVIIWGNHSSTQFPDASNAVAIVGGAQKSVSEIINDDAYLK 374
NRA Q+A K+ V V DVK IIWGNHSSTQFPDAS+A ++ V E+I D+ +L+
Sbjct: 183 NRALGQVAEKLNVHVGDVKNAIIWGNHSSTQFPDASHATVSTDRGERPVRELIADEIWLR 242
Query: 375 GAFVTTVQKRGAAVIXXXXXXXXXXXXXXXXDHMRDWFLGT-EDRWVSMGVVSDGSYGTP 551
FVT VQ+RGAAVI DHMRDW LGT + WVSMGV SDGSYG P
Sbjct: 243 EEFVTDVQQRGAAVIKARKQSSSLSAASAACDHMRDWILGTPKGTWVSMGVYSDGSYGVP 302
Query: 552 RDVVYSFPVTVTNGKWKIVEGLTISDFARQMLDATGKELVEXKQEA 689
V +SFPVT G+W +V+GL I DFAR ++ + EL E K A
Sbjct: 303 EGVFFSFPVTCEKGEWSVVQGLEIDDFARSKMETSATELKEEKSIA 348
>UniRef50_A0C8S6 Cluster: Malate dehydrogenase; n=3; Paramecium
tetraurelia|Rep: Malate dehydrogenase - Paramecium
tetraurelia
Length = 356
Score = 244 bits (596), Expect = 2e-63
Identities = 121/227 (53%), Positives = 155/227 (68%), Gaps = 2/227 (0%)
Frame = +3
Query: 15 LLAANVRIFKEQGQALDKAARKDVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLDQ 194
LLAAN RIFKEQG+AL+K A K+VKVLVVGNPANTNALI +++APSIPK NFTA+TRLDQ
Sbjct: 123 LLAANARIFKEQGEALEKYASKNVKVLVVGNPANTNALITAQFAPSIPKSNFTALTRLDQ 182
Query: 195 NRAQSQLAAKIGVPVKDVKRVIIWGNHSSTQFPDASNAVAIVGGAQKSVSEIINDDAYLK 374
NRAQS +A ++ V+DV+ +IIWGNHS+TQF D S A G ++V ++ DDA+L+
Sbjct: 183 NRAQSIIAQRVSANVEDVRNIIIWGNHSTTQFADVSQATVQQNGISQTVRGLVADDAWLQ 242
Query: 375 GAFVTTVQKRGAAVIXXXXXXXXXXXXXXXXDHMRDWFLGTED-RWVSMGVVSDGS-YGT 548
AFV V KRG A+I DH+ DW +GT++ +VSMGVV+DG YG
Sbjct: 243 KAFVEQVAKRGGAIIEKRKASSAASAASAVCDHIHDWLIGTDNGTFVSMGVVTDGKLYGI 302
Query: 549 PRDVVYSFPVTVTNGKWKIVEGLTISDFARQMLDATGKELVEXKQEA 689
V +SFP +G K+VEGL F + M+D T KEL+E K+ A
Sbjct: 303 KEQVCFSFPCICKDGNVKVVEGLKWDQFQQSMIDKTLKELLEEKEMA 349
>UniRef50_Q9UAV5 Cluster: Malate dehydrogenase; n=15; Eukaryota|Rep:
Malate dehydrogenase - Caenorhabditis elegans
Length = 336
Score = 243 bits (595), Expect = 3e-63
Identities = 117/228 (51%), Positives = 153/228 (67%), Gaps = 2/228 (0%)
Frame = +3
Query: 15 LLAANVRIFKEQGQALDKAARKDVKVLVVGNPANTNALICSKYAPS-IPKENFTAMTRLD 191
LLAANV+IFK QG+AL + A+ KV+VVGNPANTNA I +KYA IP +NF+AMTRLD
Sbjct: 101 LLAANVKIFKSQGKALAEYAKPTTKVIVVGNPANTNAFIAAKYAAGKIPAKNFSAMTRLD 160
Query: 192 QNRAQSQLAAKIGVPVKDVKRVIIWGNHSSTQFPDASNAVAIVGGAQKSVSEIINDDAYL 371
NRA +QLA K G + +VK VIIWGNHS TQFPD ++A G + + D+A+L
Sbjct: 161 HNRALAQLALKTGTTIGNVKNVIIWGNHSGTQFPDVTHATVNKNGTETDAYAAVGDNAFL 220
Query: 372 KGAFVTTVQKRGAAVIXXXXXXXXXXXXXXXXDHMRDWFLGTE-DRWVSMGVVSDGSYGT 548
+G F+ TVQKRG +I DH+ DW GT+ ++VSM V SDGSYG
Sbjct: 221 QGPFIATVQKRGGVIIEKRKLSSAMSAAKAACDHIHDWHFGTKAGQFVSMAVPSDGSYGI 280
Query: 549 PRDVVYSFPVTVTNGKWKIVEGLTISDFARQMLDATGKELVEXKQEAL 692
P+ +++SFPVT+ G+WKIV+GL+ DFA+ + AT KEL E + +AL
Sbjct: 281 PQGLIFSFPVTIEGGEWKIVQGLSFDDFAKGKIAATTKELEEERDDAL 328
>UniRef50_A1W9K7 Cluster: Malate dehydrogenase; n=95; cellular
organisms|Rep: Malate dehydrogenase - Acidovorax sp.
(strain JS42)
Length = 328
Score = 231 bits (565), Expect = 1e-59
Identities = 116/218 (53%), Positives = 144/218 (66%)
Frame = +3
Query: 15 LLAANVRIFKEQGQALDKAARKDVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLDQ 194
LLAAN +IF QG+AL+ A ++VKVLVVGNPANTNA I K AP +P +NFTAM RLD
Sbjct: 104 LLAANAQIFTAQGKALNAVASRNVKVLVVGNPANTNAYIAMKSAPDLPAKNFTAMLRLDH 163
Query: 195 NRAQSQLAAKIGVPVKDVKRVIIWGNHSSTQFPDASNAVAIVGGAQKSVSEIINDDAYLK 374
NRA SQLAAK G V D+K++ +WGNHS T + D A V G KSV + IND A+ K
Sbjct: 164 NRAASQLAAKGGFKVGDIKKLTVWGNHSPTMYAD--YRFATVDG--KSVKDAINDPAWYK 219
Query: 375 GAFVTTVQKRGAAVIXXXXXXXXXXXXXXXXDHMRDWFLGTEDRWVSMGVVSDGSYGTPR 554
F+ TV KRGAA+I DHMRDW LG++ WV+MGV S+G YG P
Sbjct: 220 DVFLPTVGKRGAAIIAARGLSSAASAANAAIDHMRDWALGSKGEWVTMGVPSNGEYGIPA 279
Query: 555 DVVYSFPVTVTNGKWKIVEGLTISDFARQMLDATGKEL 668
+V+ FPVT NG++KIVEGL I F+++ +D T EL
Sbjct: 280 GIVFGFPVTTENGEYKIVEGLPIDAFSQECIDKTLAEL 317
>UniRef50_Q23CW4 Cluster: Malate dehydrogenase, cytoplasmic,
putative; n=3; Oligohymenophorea|Rep: Malate
dehydrogenase, cytoplasmic, putative - Tetrahymena
thermophila SB210
Length = 365
Score = 230 bits (562), Expect = 3e-59
Identities = 111/226 (49%), Positives = 151/226 (66%), Gaps = 1/226 (0%)
Frame = +3
Query: 15 LLAANVRIFKEQGQALDKAARKDVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLDQ 194
LL N IFK+QGQALD A+K K LVV NPANTN LI ++ A SIPK+NF+A+TRLD
Sbjct: 141 LLTINGNIFKKQGQALDTVAKKTCKSLVVANPANTNCLILAETAKSIPKQNFSALTRLDH 200
Query: 195 NRAQSQLAAKIGVPVKDVKRVIIWGNHSSTQFPDASNAVAIVGGAQKSVSEIINDDAYLK 374
NRA SQ+A K G + DVK VIIWGNHS+TQ+PD ++ ++G K + + IND+AYL
Sbjct: 201 NRAISQIALKAGCSITDVKNVIIWGNHSTTQYPDVNHG-TVLG---KRIRQFINDEAYLN 256
Query: 375 GAFVTTVQKRGAAVIXXXXXXXXXXXXXXXXDHMRDWFLGTED-RWVSMGVVSDGSYGTP 551
AF+ VQKRG V+ DH+ DW+ GT+ +VSM V SDGSYG P
Sbjct: 257 NAFIERVQKRGGEVLAARKNSSVMSAANAVKDHLHDWYFGTKSGEFVSMAVYSDGSYGVP 316
Query: 552 RDVVYSFPVTVTNGKWKIVEGLTISDFARQMLDATGKELVEXKQEA 689
+ +++S+PVT +N +KIV+GL I +F+++ + T +EL+ K +A
Sbjct: 317 KGLIFSYPVTCSNFNYKIVQGLNIDEFSKEKIRITTEELLSEKADA 362
>UniRef50_Q2J7E7 Cluster: Malate dehydrogenase; n=24; Bacteria|Rep:
Malate dehydrogenase - Frankia sp. (strain CcI3)
Length = 329
Score = 219 bits (534), Expect = 7e-56
Identities = 105/224 (46%), Positives = 147/224 (65%), Gaps = 1/224 (0%)
Frame = +3
Query: 15 LLAANVRIFKEQGQALDKAARKDVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLDQ 194
LL+AN IFK QG+A++ A +D++VLVVGNPANTNALI +AP +P E FTAMTRLD
Sbjct: 102 LLSANGGIFKPQGEAINSGAAEDIRVLVVGNPANTNALIAQTHAPDVPAERFTAMTRLDH 161
Query: 195 NRAQSQLAAKIGVPVKDVKRVIIWGNHSSTQFPDASNAVAIVGGAQKSVSEIINDDAYLK 374
NRA +QLA K+GVP ++K++ IWGNHS+TQ+PD +A VGG +S +E + D A++
Sbjct: 162 NRAIAQLAKKLGVPSAEIKKITIWGNHSATQYPDIFHAE--VGG--RSGAEAVGDQAWIA 217
Query: 375 GAFVTTVQKRGAAVIXXXXXXXXXXXXXXXXDHMRDWFLGT-EDRWVSMGVVSDGSYGTP 551
F+ V KRGA +I DH+ W GT W S + SDGSYG P
Sbjct: 218 DEFIPRVAKRGAEIIEVRGASSAASAASAAIDHIFTWVNGTPAGDWTSAAIPSDGSYGVP 277
Query: 552 RDVVYSFPVTVTNGKWKIVEGLTISDFARQMLDATGKELVEXKQ 683
++ SFPVT + G+++IV+GL + F+R+ +DA+ +EL E ++
Sbjct: 278 EGLISSFPVTASGGRFEIVQGLELDAFSREKIDASVRELAEERE 321
>UniRef50_P61973 Cluster: Malate dehydrogenase; n=43; Bacteria|Rep:
Malate dehydrogenase - Bdellovibrio bacteriovorus
Length = 335
Score = 210 bits (513), Expect = 2e-53
Identities = 113/230 (49%), Positives = 142/230 (61%), Gaps = 8/230 (3%)
Frame = +3
Query: 15 LLAANVRIFKEQGQALDKAARKDVKVLVVGNPANTNALICSKYAPS---IPKENFTAMTR 185
LL AN +IF QG+A+ K A +VKVLVVGNPANTNA I K A + +NFTAM R
Sbjct: 103 LLTANGQIFTVQGEAIGKYANPNVKVLVVGNPANTNAYIAMKSAMKHGRVKAKNFTAMLR 162
Query: 186 LDQNRAQSQLAAKIGVPVKDVKRVIIWGNHSSTQFPDASNAVAIVGGAQKSVSEIIN--- 356
LD NRA SQLA K G PV K+V +WGNHS T +PD A A GA+ V E++
Sbjct: 163 LDHNRALSQLATKTGKPVASFKKVAVWGNHSPTMYPDVRFATA--DGAK--VPELLKLGT 218
Query: 357 --DDAYLKGAFVTTVQKRGAAVIXXXXXXXXXXXXXXXXDHMRDWFLGTEDRWVSMGVVS 530
DA+ K F+ TV KRGAA+I DH+RDW+LGT WV+MG+ S
Sbjct: 219 AEGDAWNKDTFIPTVGKRGAAIIEARGLSSAASAASAAVDHIRDWWLGTNGEWVTMGIPS 278
Query: 531 DGSYGTPRDVVYSFPVTVTNGKWKIVEGLTISDFARQMLDATGKELVEXK 680
DGSY P ++Y FPVT NG+++IV+GL I F+R+ ++ T KEL E K
Sbjct: 279 DGSYDIPEGIMYGFPVTCKNGEYEIVKGLEIDAFSREKMNNTLKELNEEK 328
>UniRef50_A0BHM8 Cluster: Malate dehydrogenase; n=3; Paramecium
tetraurelia|Rep: Malate dehydrogenase - Paramecium
tetraurelia
Length = 360
Score = 192 bits (467), Expect = 9e-48
Identities = 100/223 (44%), Positives = 135/223 (60%), Gaps = 1/223 (0%)
Frame = +3
Query: 15 LLAANVRIFKEQGQALDKAARKDVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLDQ 194
LL N +IF E G+ ++ A +D+KV+VVGNP NTN LI + IPKENFTAMTRLD
Sbjct: 137 LLKDNGKIFTETGKYINDHASRDIKVVVVGNPCNTNCLILANQIKDIPKENFTAMTRLDH 196
Query: 195 NRAQSQLAAKIGVPVKDVKRVIIWGNHSSTQFPDASNAVAIVGGAQKSVSEIINDDAYLK 374
NRAQ QLA K+GV D++++ I+GNHS T P A K+ + D ++
Sbjct: 197 NRAQHQLADKLGVHTSDIRKIAIFGNHSPTMVPYIDQMTA------KNHKATV-DQQWVT 249
Query: 375 GAFVTTVQKRGAAVIXXXXXXXXXXXXXXXXDHMRDWFLGT-EDRWVSMGVVSDGSYGTP 551
F+ TVQ+RGA +I +H+ W GT E + SM + SDGSYG P
Sbjct: 250 QTFIPTVQQRGAEIIKARKLSSAASAGNAAMNHITTWVNGTAEGDYTSMAIPSDGSYGVP 309
Query: 552 RDVVYSFPVTVTNGKWKIVEGLTISDFARQMLDATGKELVEXK 680
+ +++SFPVTV NGK+ IV+GL IS F + +LD T KELV+ +
Sbjct: 310 KGLIFSFPVTVKNGKYSIVQGLPISPFYQGLLDKTIKELVDER 352
>UniRef50_Q8I8I5 Cluster: Malate dehydrogenase; n=2; Eukaryota|Rep:
Malate dehydrogenase - Mastigamoeba balamuthi
(Phreatamoeba balamuthi)
Length = 382
Score = 190 bits (462), Expect = 4e-47
Identities = 100/232 (43%), Positives = 140/232 (60%), Gaps = 5/232 (2%)
Frame = +3
Query: 9 RYLLAANVRIFKEQGQALDKAARKDVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRL 188
R LLA N IFK QG+A+ A DV+VLVV NPANTN L+ S+ AP+IP+ + + MTRL
Sbjct: 143 RDLLAQNAAIFKAQGKAVSDYADPDVRVLVVANPANTNCLVFSRCAPNIPRTHVSCMTRL 202
Query: 189 DQNRAQSQLAAKIGVPVKDVKRVIIWGNHSSTQFPDASNAVA---IVGGAQKSVSEIIND 359
D NR+++Q+A ++GV ++V I+WGNHS TQ+PD A GA +IND
Sbjct: 203 DHNRSKAQIAERVGVETRNVHNAIVWGNHSGTQYPDLRFARVDDFPTKGASTPARALIND 262
Query: 360 DAYLKGAFVTTVQKRGAAVIXXXXXXXXXXXXXXXXDHMRDWFLGT-EDRWVSMGVVSDG 536
D ++ FV TVQ+RG VI D +RDW LGT VSMGVV+DG
Sbjct: 263 DEWVFKTFVPTVQQRGYKVIEARKLSSAASAATAACDAIRDWVLGTPAGEMVSMGVVTDG 322
Query: 537 S-YGTPRDVVYSFPVTVTNGKWKIVEGLTISDFARQMLDATGKELVEXKQEA 689
S YG D+V+S PV + G++ +V+ L + +++ L A+ +EL+ + EA
Sbjct: 323 SKYGIAEDLVFSMPVQCSGGEYTVVDNLPVDAESQRRLRASEQELIAERTEA 374
>UniRef50_Q4Q7X6 Cluster: Cytosolic malate dehydrogenase, putative;
n=7; Eukaryota|Rep: Cytosolic malate dehydrogenase,
putative - Leishmania major
Length = 324
Score = 187 bits (455), Expect = 3e-46
Identities = 109/228 (47%), Positives = 131/228 (57%), Gaps = 3/228 (1%)
Frame = +3
Query: 15 LLAANVRIFKEQGQALDKAARKDVKVLVVGNPANTNALICSKYAPS-IPKENFTAMTRLD 191
LL N RIFKEQG+A+ A D +V+VVGNPANTNALI K A + + TAMTRLD
Sbjct: 100 LLEMNARIFKEQGEAIAAVAASDCRVVVVGNPANTNALILLKSAQGKLNPRHVTAMTRLD 159
Query: 192 QNRAQSQLAAKIGVPVKDVKRVIIWGNHSSTQFPDASNAVAIVGGAQKSVSEIINDDAYL 371
NRA S LA K GVPV V+ VIIWGNHSSTQ PD +AV +G E I DDA L
Sbjct: 160 HNRALSLLARKAGVPVSQVRNVIIWGNHSSTQVPDTDSAV--IG--TTPAREAIKDDA-L 214
Query: 372 KGAFVTTVQKRGAAVIXXXXXXXXXXXXXXXXDHMRDWFLGT-EDRWVSMGVVSD-GSYG 545
FV V+ RGA +I DH+ DW GT E +VSMGV SD YG
Sbjct: 215 DDDFVQVVRGRGAEIIQLRGLSSAMSAAKAAVDHVHDWIHGTPEGVYVSMGVYSDENPYG 274
Query: 546 TPRDVVYSFPVTVTNGKWKIVEGLTISDFARQMLDATGKELVEXKQEA 689
P +++SFP T G+W +V G D +Q L +T EL E + +A
Sbjct: 275 VPSGLIFSFPCTCHAGEWTVVSGKLNGDLGKQRLASTIAELQEERAQA 322
>UniRef50_Q4D123 Cluster: Malate dehydrogenase; n=9; Eukaryota|Rep:
Malate dehydrogenase - Trypanosoma cruzi
Length = 332
Score = 180 bits (439), Expect = 2e-44
Identities = 104/231 (45%), Positives = 131/231 (56%), Gaps = 3/231 (1%)
Frame = +3
Query: 9 RYLLAANVRIFKEQGQALDKAARKDVKVLVVGNPANTNALICSKYAPS-IPKENFTAMTR 185
R LL N IF E G+ L + A KD V VVGNP NTNAL+ + I +N +A+TR
Sbjct: 102 RDLLQKNAAIFSEHGRLLGELASKDCHVCVVGNPVNTNALVLLNASNGKIKPKNVSALTR 161
Query: 186 LDQNRAQSQLAAKIGVPVKDVKRVIIWGNHSSTQFPDASNAVAIVGGAQKSVSEIINDDA 365
LD NR+ + +A + V+DVK IIWGNHS TQ PD ++A V G V E I DDA
Sbjct: 162 LDHNRSLALVAERANAHVRDVKNCIIWGNHSGTQVPDVNSAT--VKGV--PVREAIKDDA 217
Query: 366 YLKGAFVTTVQKRGAAVIXXXXXXXXXXXXXXXXDHMRDWFLGT-EDRWVSMGVVSDGS- 539
YL G F+TTVQ+RG +I D + DW LGT VSM V SDG+
Sbjct: 218 YLDGEFMTTVQQRGYEIIRWRGNSSALSAANAAVDQVHDWVLGTPTGTHVSMAVYSDGNP 277
Query: 540 YGTPRDVVYSFPVTVTNGKWKIVEGLTISDFARQMLDATGKELVEXKQEAL 692
YG P +V+SFPVT + G+W VE I+ + L AT KEL E + E+L
Sbjct: 278 YGVPPGLVFSFPVTCSGGEWHFVENACITPSVAKHLAATTKELEEERAESL 328
>UniRef50_Q86S08 Cluster: NAD-specific malate dehydrogenase 1; n=2;
Entamoeba histolytica|Rep: NAD-specific malate
dehydrogenase 1 - Entamoeba histolytica
Length = 355
Score = 179 bits (436), Expect = 5e-44
Identities = 95/224 (42%), Positives = 135/224 (60%), Gaps = 1/224 (0%)
Frame = +3
Query: 15 LLAANVRIFKEQGQALDKAARKDVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLDQ 194
L+ N RI KEQ AL A V+VLVV NPANTNAL+ + A I + T +TRLDQ
Sbjct: 119 LIGINTRIMKEQALALKNFANPHVRVLVVANPANTNALVVANNA-GIDVKQITCLTRLDQ 177
Query: 195 NRAQSQLAAKIGVPVKDVKRVIIWGNHSSTQFPDASNAVAIVGGAQKSVSEIINDDAYLK 374
NRA +Q+A+K+ V+DV +WGNHS Q PD S+AV K V++++ ++++L+
Sbjct: 178 NRAIAQIASKLNCKVEDVSDAFVWGNHSEKQCPDISHAVVQTPNGPKRVADLV-EESWLE 236
Query: 375 GAFVTTVQKRGAAVIXXXXXXXXXXXXXXXXDHMRDWFLGT-EDRWVSMGVVSDGSYGTP 551
+F TVQ+RGA VI DH RDW LGT +++ V MGV S+G YG P
Sbjct: 237 -SFNKTVQERGAKVIEMRKASSAASAAKAIVDHFRDWCLGTNKEKIVCMGVYSEGQYGIP 295
Query: 552 RDVVYSFPVTVTNGKWKIVEGLTISDFARQMLDATGKELVEXKQ 683
+ + +S PV G++ IV+ L +S+ R ML + +EL+E K+
Sbjct: 296 KGIFFSMPVVCYGGEYHIVDDLVLSESTRTMLKNSEEELLEEKK 339
>UniRef50_Q9GPV2 Cluster: Cytosolic malate dehydrogenase; n=4;
Trichomonadida|Rep: Cytosolic malate dehydrogenase -
Tetratrichomonas gallinarum
Length = 314
Score = 177 bits (431), Expect = 2e-43
Identities = 101/229 (44%), Positives = 134/229 (58%), Gaps = 4/229 (1%)
Frame = +3
Query: 15 LLAANVRIFKEQGQALDKAARKDVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLDQ 194
LLA N IF QG+AL A+KDVKVLVVGNPANTN LI AP++ K+N+ AMTRLD
Sbjct: 82 LLAKNGGIFTVQGKALSDFAKKDVKVLVVGNPANTNCLIAQASAPNLSKKNWCAMTRLDH 141
Query: 195 NRAQSQLAAKIGVPVKDVKRVIIWGNHSSTQFPDASNA-VAIVGGAQKSVSEIINDDAYL 371
NR LAAK GV + V VI+WGNHS+TQ PDA +A V + G K ++ D YL
Sbjct: 142 NRMVGALAAKFGVTPEKVHNVIVWGNHSNTQVPDAYHATVDLPEGTVKVADKL--DAEYL 199
Query: 372 KGAFVTTVQKRGAAVIXXXXXXXXXXXXXXXXDHMRDWFLGTED-RWVSMGV-VSDGS-Y 542
+ F + RG AVI ++DW GT+D +VSM + V D Y
Sbjct: 200 EKEFAPMIATRGGAVIKMRGASSAASAANAALTCVKDWIYGTKDGEFVSMAIPVPDNEPY 259
Query: 543 GTPRDVVYSFPVTVTNGKWKIVEGLTISDFARQMLDATGKELVEXKQEA 689
G + ++YSFP T +G+ K+VE L +++ + + AT +ELV K+ A
Sbjct: 260 GVKQGIIYSFPCTCKDGEVKVVENLERNEWVKSKMVATEQELVGEKETA 308
>UniRef50_A0D8T3 Cluster: Malate dehydrogenase; n=2; Paramecium
tetraurelia|Rep: Malate dehydrogenase - Paramecium
tetraurelia
Length = 322
Score = 177 bits (430), Expect = 3e-43
Identities = 89/225 (39%), Positives = 134/225 (59%), Gaps = 2/225 (0%)
Frame = +3
Query: 15 LLAANVRIFKEQGQALDKAARKDVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLDQ 194
LL N IF +QGQ L++ A+ VKVLVV NP+NTN + IP++NFT++ +LD
Sbjct: 103 LLQMNREIFIQQGQILNEQAKSTVKVLVVANPSNTNCATLAHQCTKIPQQNFTSLMQLDH 162
Query: 195 NRAQSQLAAKIGVPVKDVKRVIIWGNHSSTQFPDASNAVAIVGGAQKSVSEIINDDAYLK 374
NR S LA + + +K+VIIWGNHS TQ+PD ++ +I+ G K SE + D +L+
Sbjct: 163 NRCVSTLAREANTTIDQIKKVIIWGNHSLTQYPDMTH--SIING--KQASETFSKD-FLR 217
Query: 375 GAFVTTVQKRGAAVIXXXXXXXXXXXXXXXXDHMRDWFLGT-EDRWVSMGVVSDGS-YGT 548
A + VQ+RG ++ DH+R WFLGT +D W S GV+SDG+ YG
Sbjct: 218 NALIQQVQQRGGQILQLSRGASTISGAIAVKDHLRTWFLGTSQDNWTSFGVISDGNHYGI 277
Query: 549 PRDVVYSFPVTVTNGKWKIVEGLTISDFARQMLDATGKELVEXKQ 683
P+ + +S PVT ++K+V + + DF++Q + + EL + +Q
Sbjct: 278 PKGICFSLPVTCKEFEFKVVGDVELDDFSKQRIQLSLVELQKEQQ 322
>UniRef50_Q9Z6N1 Cluster: Malate dehydrogenase; n=8;
Chlamydiaceae|Rep: Malate dehydrogenase - Chlamydia
pneumoniae (Chlamydophila pneumoniae)
Length = 328
Score = 168 bits (409), Expect = 1e-40
Identities = 91/224 (40%), Positives = 126/224 (56%), Gaps = 2/224 (0%)
Frame = +3
Query: 15 LLAANVRIFKEQGQALDKAARKDVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLDQ 194
LL N +IF QG AL+ AA++D K+ VVGNP NTN I K+AP + ++NF AM RLDQ
Sbjct: 103 LLKQNGQIFSLQGAALNTAAKRDAKIFVVGNPVNTNCWIAMKHAPRLHRKNFHAMLRLDQ 162
Query: 195 NRAQSQLAAKIGVPVKDVKRVIIWGNHSSTQFPDASNAVAIVGGAQKSVSEIINDDAYLK 374
NR S LA + VP+++V RV+IWGNHS+ Q PD + A I G K +E+I D +L+
Sbjct: 163 NRMHSMLAHRAEVPLEEVSRVVIWGNHSAKQVPDFTQA-RISG---KPAAEVIGDRDWLE 218
Query: 375 GAFVTTVQKRGAAVIXXXXXXXXXXXXXXXXDHMRDWFLGTEDRWVSMGVVSD-GSYGTP 551
V +VQ RG+AVI + R F D W S GV SD YG P
Sbjct: 219 NILVHSVQNRGSAVIEARGKSSAASASRALAEAARSIFCPKSDEWFSSGVCSDHNPYGIP 278
Query: 552 RDVVYSFPV-TVTNGKWKIVEGLTISDFARQMLDATGKELVEXK 680
D+++ FP + +G ++I+ GL F R + + E+ + K
Sbjct: 279 EDLIFGFPCRMLPSGDYEIIPGLPWEPFIRNKIQISLDEIAQEK 322
>UniRef50_P15719 Cluster: Malate dehydrogenase [NADP], chloroplast
precursor; n=62; cellular organisms|Rep: Malate
dehydrogenase [NADP], chloroplast precursor - Zea mays
(Maize)
Length = 432
Score = 163 bits (397), Expect = 3e-39
Identities = 95/226 (42%), Positives = 130/226 (57%), Gaps = 3/226 (1%)
Frame = +3
Query: 15 LLAANVRIFKEQGQALDKAARKDVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLDQ 194
LL N +IF +QG+AL+ A ++ +VLVVGNP NTNALIC K AP+IP +NF A+TRLD+
Sbjct: 186 LLDINGQIFADQGKALNAVASRNDEVLVVGNPCNTNALICLKNAPNIPAKNFHALTRLDE 245
Query: 195 NRAQSQLAAKIGVPVKDVKRVIIWGNHSSTQFPDASNAVAIVGGAQKSVSEIINDDAYLK 374
NRA+ QLA K GV V V IWGNHS+TQ PD NA I G + V E+I D +L+
Sbjct: 246 NRAKCQLALKAGVFYDKVSNVTIWGNHSTTQVPDFLNA-KIDG---RPVKEVIKDTKWLE 301
Query: 375 GAFVTTVQKRGAAVIXXXXXXXXXXXXXXXXDHMRDWFLGT-EDRWVSMGVVSDGS-YGT 548
F TVQKRG +I D +R T E W S GV + G+ YG
Sbjct: 302 EEFTLTVQKRGGVLIQKWGRSSAASTAVSIVDAIRSLVTPTPEGDWFSTGVYTTGNPYGI 361
Query: 549 PRDVVYSFPV-TVTNGKWKIVEGLTISDFARQMLDATGKELVEXKQ 683
D+V+S P + +G +++ + + DF + + + EL+ K+
Sbjct: 362 AEDIVFSMPCRSKGDGDYELASDVLMDDFLWERIKKSEAELLAEKK 407
>UniRef50_UPI000065DBFD Cluster: Malate dehydrogenase, cytoplasmic
(EC 1.1.1.37) (Cytosolic malate dehydrogenase).; n=1;
Takifugu rubripes|Rep: Malate dehydrogenase, cytoplasmic
(EC 1.1.1.37) (Cytosolic malate dehydrogenase). -
Takifugu rubripes
Length = 382
Score = 154 bits (374), Expect = 2e-36
Identities = 77/164 (46%), Positives = 105/164 (64%), Gaps = 3/164 (1%)
Frame = +3
Query: 210 QLAAKIGVPVKDVKRVIIWGNHSSTQFPDASNAVAIVGGAQKSVSEIINDDAYLKGAFVT 389
++A + GVP VK VIIWGNHSSTQ+PD + + + G++ + + I D+A+LKG F+
Sbjct: 215 KVAMRCGVPATHVKNVIIWGNHSSTQYPDVHHCMVNMSGSELTCFDAIKDEAWLKGEFIA 274
Query: 390 TVQKRGAAVIXXXXXXXXXXXXXXXXDHMRDWFLGT-EDRWVSMGVVSDG-SYGTPRDVV 563
TVQ+RGAAVI DHMRD + GT E ++SMGV S G SYG P D++
Sbjct: 275 TVQQRGAAVIKARKLSSAMSAAKAICDHMRDIWTGTPEGEFISMGVYSTGNSYGVPDDLI 334
Query: 564 YSFPVTVTNGK-WKIVEGLTISDFARQMLDATGKELVEXKQEAL 692
YSFPV + K WKIV+GL I+ F++ +DAT EL+E + AL
Sbjct: 335 YSFPVQIHKDKSWKIVDGLGINSFSQTKMDATAAELMEERDTAL 378
Score = 36.7 bits (81), Expect = 0.54
Identities = 20/34 (58%), Positives = 24/34 (70%), Gaps = 1/34 (2%)
Frame = +3
Query: 15 LLAANVRIFKEQGQALDKAARKDVKVLV-VGNPA 113
LL ANV IFK QG AL+K ++K VKV + G PA
Sbjct: 191 LLKANVAIFKSQGSALEKFSKKTVKVAMRCGVPA 224
>UniRef50_A7RRY2 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 462
Score = 148 bits (359), Expect = 1e-34
Identities = 82/238 (34%), Positives = 133/238 (55%), Gaps = 11/238 (4%)
Frame = +3
Query: 12 YLLAANVRIFKEQGQALDKAARKDVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLD 191
YLL+ + ++F++ G+AL+ A+ D KVL G PAN + I SK+APSI K+NF +++R++
Sbjct: 228 YLLS-HAKLFRDYGKALEAHAKPDCKVLTAGGPANFSTFIASKFAPSIQKKNFVSLSRIE 286
Query: 192 QNRAQSQLAAKIGVPVKDVKRVIIWGNHSSTQFPDASNA------VAIVG----GAQKSV 341
+NRA+ +A ++ V +K +I+WGN +PDAS+A AI G G + V
Sbjct: 287 ENRAKGLIAKRLNVNTAGIKDLIVWGNPGFNHYPDASHARVDGFDGAIWGPHVPGFTRPV 346
Query: 342 SEIINDDAYLKGAFVTTVQKRGAAVIXXXXXXXXXXXXXXXXDHMRDWF-LGTEDRWVSM 518
E+++D+ +L G FV ++K ++DW + D W S+
Sbjct: 347 PEMVHDNKWLSGEFVEVLKKPSEG-------ENALMGSVAVKSLLQDWCQCASSDMW-SL 398
Query: 519 GVVSDGSYGTPRDVVYSFPVTVTNGKWKIVEGLTISDFARQMLDATGKELVEXKQEAL 692
GV+S+G Y P + +SFPV T G W++VEGL +SD +++L +E +E L
Sbjct: 399 GVISEGWYDIPEGIAFSFPVKFTGGSWQVVEGLALSDSLKEVLKNIAQEAKAETEEVL 456
>UniRef50_Q86S07 Cluster: NAD-specific malate dehydrogenase 2; n=1;
Entamoeba histolytica|Rep: NAD-specific malate
dehydrogenase 2 - Entamoeba histolytica
Length = 329
Score = 145 bits (351), Expect = 1e-33
Identities = 82/223 (36%), Positives = 120/223 (53%), Gaps = 1/223 (0%)
Frame = +3
Query: 15 LLAANVRIFKEQGQALDKAARKDVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLDQ 194
L+ N ++ + G+AL + KDV+V+VV NPANTNA + K + IP E+ TA+TRLDQ
Sbjct: 108 LINVNKKVMEMNGKALGTYSNKDVRVVVVANPANTNAYVICKTS-GIPPEHITALTRLDQ 166
Query: 195 NRAQSQLAAKIGVPVKDVKRVIIWGNHSSTQFPDASNAVAIVGGAQKSVSEIINDDAYLK 374
NRA + +A ++G + V +I+WGNHS+T PD S + K ++ I D
Sbjct: 167 NRATAFVANEVGCQPEFVHNIIVWGNHSNTMQPDLSYSYLADQNGIKPLANCIED----F 222
Query: 375 GAFVTTVQKRGAAVIXXXXXXXXXXXXXXXXDHMRDWFLGTEDR-WVSMGVVSDGSYGTP 551
AF V+ RG VI H++DW GT+ VSMGV S+G YG
Sbjct: 223 DAFTEKVRCRGEEVISTRKASSAGSAAHAICQHIKDWIYGTKPGIMVSMGVSSNGEYGID 282
Query: 552 RDVVYSFPVTVTNGKWKIVEGLTISDFARQMLDATGKELVEXK 680
+ YS PVT + G++ IV+ L I + L + EL++ +
Sbjct: 283 TGLFYSMPVTCSEGEYHIVDSLVIEPRIKDSLILSELELIDER 325
>UniRef50_Q7QQW5 Cluster: Malate dehydrogenase; n=2; Giardia
intestinalis|Rep: Malate dehydrogenase - Giardia lamblia
ATCC 50803
Length = 331
Score = 144 bits (350), Expect = 1e-33
Identities = 86/230 (37%), Positives = 124/230 (53%), Gaps = 5/230 (2%)
Frame = +3
Query: 15 LLAANVRIFKEQGQALDKAARKDVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLDQ 194
LL+ N IF+ QG A+++ A+ ++LV+GNPANTNAL+ S IPK N TAM+RLD
Sbjct: 102 LLSKNKGIFQIQGAAINEHAKPTCRILVIGNPANTNALVLSTQLTKIPKTNVTAMSRLDH 161
Query: 195 NRAQSQLAAKIGVPVKDVKRVIIWGNHSSTQFPDASNAVAIVGGA--QKSVSEIINDDAY 368
NRA Q+A K+GV + V + GNHS+T P V G ++ V ++ D +
Sbjct: 162 NRAVGQVAGKLGVRTNRISNVWVAGNHSNTMVPIVDCGVIYDEGLKDKQPVKPMLPAD-W 220
Query: 369 LKGAFVTTVQKRGAAVIXXXXXXXXXXXXXXXXDHMRDWFLGTE-DRWVSMG-VVSDGS- 539
+KG FV V+ RG AVI DH+RDW +GT+ +VS ++ +G+
Sbjct: 221 IKGEFVPCVRGRGTAVIEARGHSSSASAANAAIDHVRDWHMGTKPGAFVSCSLLIEEGNP 280
Query: 540 YGTPRDVVYSFPVTVTNGKWKIVEGLTISDFARQMLDATGKELVEXKQEA 689
YG + YS P + GKW+IV+ D + +LD E +EA
Sbjct: 281 YGIAPGIFYSMPCSCVGGKWQIVK----LDLPKDVLDEMKLSEAELMKEA 326
>UniRef50_A2G340 Cluster: Malate dehydrogenase; n=18;
Trichomonadinae|Rep: Malate dehydrogenase - Trichomonas
vaginalis G3
Length = 339
Score = 143 bits (346), Expect = 4e-33
Identities = 80/230 (34%), Positives = 124/230 (53%), Gaps = 4/230 (1%)
Frame = +3
Query: 15 LLAANVRIFKEQGQALDKAARKDVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLDQ 194
L+ +N IFK G+ L + A+ VKVLV+GNP NTNA I +A ++ ENF++++ LDQ
Sbjct: 100 LIGSNSIIFKNTGEWLSQYAKPTVKVLVIGNPDNTNAEIALLHAKNLKPENFSSLSLLDQ 159
Query: 195 NRAQSQLAAKIGVPVKDVKRVIIWGNHSSTQFPDASNAVAIVGGAQKSVSEIINDDAYLK 374
NRA +A K+GV V D+ +++WGNH + D + A G + V++++ D+ Y +
Sbjct: 160 NRAYHAIAEKLGVKVTDLHDIVVWGNHGESMVADLTQATFEKDGKIQKVTDVL-DEKYRE 218
Query: 375 GAFVTTVQKRGAAVIXXXXXXXXXXXXXXXXDHMRDWFLGTEDRWV-SMG--VVSDGSYG 545
F + RG ++ HM+ W GT+ V SMG V + YG
Sbjct: 219 ETFFKFISHRGWDIVEYRGFSSAASPTKASIQHMKAWLFGTKPGEVLSMGIPVPENNKYG 278
Query: 546 TPRDVVYSFPVTV-TNGKWKIVEGLTISDFARQMLDATGKELVEXKQEAL 692
VV+S P TV +G +VE ++D+ R+ L+ T K+L K+ AL
Sbjct: 279 LKPGVVFSLPCTVDKDGNVHVVETYKVNDWLREKLEFTEKDLFNEKEIAL 328
>UniRef50_Q9GSY3 Cluster: Malate dehydrogenase; n=1; Hypotrichomonas
acosta|Rep: Malate dehydrogenase - Hypotrichomonas
acosta
Length = 318
Score = 140 bits (340), Expect = 2e-32
Identities = 81/232 (34%), Positives = 123/232 (53%), Gaps = 6/232 (2%)
Frame = +3
Query: 15 LLAANVRIFKEQGQALDKAARKDVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLDQ 194
LL N IFK G+AL + A+ V+ LVVGNP N+N L+ AP + ENF+ M LD
Sbjct: 81 LLTKNTPIFKAIGEALSEYAKPTVRALVVGNPVNSNCLVAMLNAPKLSAENFSCMCTLDH 140
Query: 195 NRAQSQLAAKIGVPVKDVKRVIIWGNHSSTQFPDASNAVAI--VGGAQKSVSEIINDDAY 368
NR+ S++A+ + VP+ V V +WGNH+ TQ PD ++ G +K+ E+ +
Sbjct: 141 NRSVSRIASHLKVPIDHVYHVAVWGNHAETQVPDITHVEVTDENGTHRKAFDELCRIEP- 199
Query: 369 LKGAFVTTVQKRGAAVIXXXXXXXXXXXXXXXXDHMRDWFLGTE-DRWVSMGV-VSDG-S 539
+ F+ + +R V+ HMR W GT + W+S+G+ V +G S
Sbjct: 200 -EPDFIEVIAQRAWKVLEMRGKTSAGSAVNAALCHMRAWLFGTRPNDWISLGIPVPEGNS 258
Query: 540 YGTPRDVVYSFPVTV-TNGKWKIVEGLTISDFARQMLDATGKELVEXKQEAL 692
YG +++SFP TV GK IVE L ++ + + T K+L E ++ AL
Sbjct: 259 YGIKPGIIFSFPCTVDEKGKVHIVENLELNPEIKTKIAQTEKDLFEERETAL 310
>UniRef50_Q2SKL3 Cluster: Malate dehydrogenase; n=1; Hahella
chejuensis KCTC 2396|Rep: Malate dehydrogenase - Hahella
chejuensis (strain KCTC 2396)
Length = 193
Score = 139 bits (337), Expect = 5e-32
Identities = 81/182 (44%), Positives = 103/182 (56%), Gaps = 1/182 (0%)
Frame = +3
Query: 18 LAANVRIFKEQGQALDKAARKDVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLDQN 197
L N IF EQG+AL K A+ VK LVVGNPANTNALI A +P F+A+ RLD N
Sbjct: 7 LQENPSIFVEQGKALGKVAKDTVKTLVVGNPANTNALIAWANARYLPHHQFSALMRLDHN 66
Query: 198 RAQSQLAAKIGVPVKDVKRVIIWGNHSSTQFPDASNAVAIVGGAQKSVSEIINDDAYLKG 377
RA L+ KIG+ + +KR+ IWGNH+ST FPDAS+ + I G + D + +
Sbjct: 67 RALGFLSRKIGINPRRIKRLTIWGNHASTLFPDASH-LRIDG----QPIRMALDMNWYRD 121
Query: 378 AFVTTVQKRGAAVIXXXXXXXXXXXXXXXXDHMRDWFLGTED-RWVSMGVVSDGSYGTPR 554
+ VQ+RG AVI DH+RDW GTE+ +VSMGV+S G
Sbjct: 122 IMIDQVQQRGTAVISCKGRTSSSSAAQAIIDHLRDWRFGTEEGDFVSMGVLSQGDRKPVA 181
Query: 555 DV 560
DV
Sbjct: 182 DV 183
>UniRef50_A2E124 Cluster: Malate dehydrogenase; n=6;
Trichomonadidae|Rep: Malate dehydrogenase - Trichomonas
vaginalis G3
Length = 332
Score = 138 bits (335), Expect = 9e-32
Identities = 85/226 (37%), Positives = 120/226 (53%), Gaps = 4/226 (1%)
Frame = +3
Query: 27 NVRIFKEQGQALDKAARKDVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLDQNRAQ 206
N I+ E G+AL A+ VKVLV+G P NTNAL+ A ++ +NF AMTRLD NRA
Sbjct: 104 NASIYSEHGRALSDFAKPTVKVLVIGMPTNTNALVAMTAAVNLSPKNFCAMTRLDHNRAV 163
Query: 207 SQLAAKIGVPVKDVKRVIIWGNHSSTQFPDASNAVAIVGGAQKSVSEIINDDAYLKGAFV 386
+A K+GV V +V+IWGN SS+Q PD SNA + + E ++++ Y+ F
Sbjct: 164 YSIAQKLGVHHSKVYKVVIWGNRSSSQIPDVSNAEYQDETGRHHILEKVSEE-YVNTEFS 222
Query: 387 TTVQKRGAAVIXXXXXXXXXXXXXXXXDHMRDWFLGT-EDRWVSMGV-VSDGS-YGTPRD 557
+ + +RG V MRDW GT D +VSM V V + S YG
Sbjct: 223 SDLAQRGNKVTMMRGASSAASAATAAIQCMRDWLYGTPADNFVSMSVPVPESSPYGVKPG 282
Query: 558 VVYSFPVTV-TNGKWKIVEGLTISDFARQMLDATGKELVEXKQEAL 692
+ +SFP TV G +VEGL + +AT K++ + ++E L
Sbjct: 283 IFFSFPCTVDKEGNIHVVEGLPVD-------EATAKKIKQQEEEIL 321
>UniRef50_Q8T773 Cluster: Putative uncharacterized protein; n=1;
Branchiostoma floridae|Rep: Putative uncharacterized
protein - Branchiostoma floridae (Florida lancelet)
(Amphioxus)
Length = 522
Score = 122 bits (293), Expect = 1e-26
Identities = 72/231 (31%), Positives = 119/231 (51%), Gaps = 10/231 (4%)
Frame = +3
Query: 18 LAANVRIFKEQGQALDKAARKDVKVLVVGN-PANTNALICSKYAPSIPKENFTAMTRLDQ 194
+ V +K +A+++ A KD++VLV G P N+ I + PSIP++N A+ ++ +
Sbjct: 228 METKVSFYKRVAEAINQTASKDIRVLVAGTGPLNSLVSILIDHTPSIPRQNIAAVAQVKE 287
Query: 195 NRAQSQLAAKIGVPVKDVKRVIIWGNHSSTQFPDASNAV------AIVGGAQKS--VSEI 350
+A+S LA ++ V V VI+WGN T + D S A AI G S VSE+
Sbjct: 288 RQAKSLLAKRLTVNSAGVCDVIVWGNVGGTTYTDVSRARVHGYDGAIWGPPSYSCSVSEM 347
Query: 351 INDDAYLKGAFVTTVQKRGAAVIXXXXXXXXXXXXXXXXDHMRDWFLGT-EDRWVSMGVV 527
++D+ +L+G F+ +Q R + + W+ G+ E + S+ V
Sbjct: 348 VHDNKWLEGEFLEQLQSRSHTIQDSLQHSADLSMAAAISSTLSYWWNGSPEGQLFSLAVC 407
Query: 528 SDGSYGTPRDVVYSFPVTVTNGKWKIVEGLTISDFARQMLDATGKELVEXK 680
S+G Y P VV+SFPV G W++V+ + +++ R ML + +LVE K
Sbjct: 408 SEGFYNIPEGVVFSFPVMFHKGSWEVVQDIDMNEDMRVMLSSITAQLVEEK 458
>UniRef50_Q08BZ4 Cluster: Zgc:153922; n=4; Danio rerio|Rep:
Zgc:153922 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 447
Score = 109 bits (262), Expect = 6e-23
Identities = 73/220 (33%), Positives = 106/220 (48%), Gaps = 10/220 (4%)
Frame = +3
Query: 39 FKEQGQALDKAARKDVKVLVVGNP-ANTNALICSKYAPSIPKENFTAMTRLDQNRAQSQL 215
F GQ ++ A+KDV+VLV G+ N + + APSI NF AMT + A++QL
Sbjct: 213 FHRYGQLIETNAQKDVRVLVAGDFFINMKCSLLIENAPSIDSRNFVAMTTQLEYEARTQL 272
Query: 216 AAKIGVPVKDVKRVIIWGNHSSTQFPDASNAV------AIVG--GAQKSVSEIINDDAYL 371
A K+ V D+ VI+WGN S + D A AI G G + V E+I D +L
Sbjct: 273 AQKLSVKTSDITNVIVWGNISGSFHIDLQRAKVFRYDGAIRGPDGFSQHVMEMIYDWKWL 332
Query: 372 KGAFVTTVQKRGAAVIXXXXXXXXXXXXXXXXDHMRDWFLGTEDRWV-SMGVVSDGSYGT 548
K F + + K A + ++ W V S+GV+S G +G
Sbjct: 333 KTDFRSLLHKHRATISSKTNKATAISTTNAILAILKAWNNAESPEEVFSLGVLSTGQFGI 392
Query: 549 PRDVVYSFPVTVTNGKWKIVEGLTISDFARQMLDATGKEL 668
P +V+S PV+ T+G W + +T++D R LDA EL
Sbjct: 393 PAGLVFSMPVSFTDGHWSVRSDVTVTDELRVNLDACADEL 432
>UniRef50_UPI00015B5AB4 Cluster: PREDICTED: similar to CG5362-PA;
n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
CG5362-PA - Nasonia vitripennis
Length = 358
Score = 106 bits (254), Expect = 6e-22
Identities = 71/203 (34%), Positives = 102/203 (50%), Gaps = 1/203 (0%)
Frame = +3
Query: 42 KEQGQALDKAARKDVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLDQNRAQSQLAA 221
K+ AL+K A+ DVK++ +GN T+A + S+YAPSIPK N T +T + Q A S +A
Sbjct: 128 KKMAIALEKFAKIDVKIITLGN---TSARLISEYAPSIPKNNITGVTLVLQRLAASAIAK 184
Query: 222 KIGVPVKDVKRVIIWGNHSSTQFPDASNAVAIVGGAQKSVSEIINDDAYLKGAFVTTVQK 401
K G DVK +IIWG +S + FP +A +KSV I DD + K T+ K
Sbjct: 185 KTGRLPSDVKNLIIWGTNSRSVFPYCGHAKF---SDEKSVINEICDDKWFK----KTLPK 237
Query: 402 RGAAVIXXXXXXXXXXXXXXXXDHMRDWFLGT-EDRWVSMGVVSDGSYGTPRDVVYSFPV 578
V +H + GT W M VVSDGSY +SFP+
Sbjct: 238 LVEGVF--RKCRYRISEALALAEHCKLLVQGTPPGEWTCMSVVSDGSYDVTPGHFFSFPL 295
Query: 579 TVTNGKWKIVEGLTISDFARQML 647
+G W+IV L + D+ ++++
Sbjct: 296 YCRDGNWEIVRDLYVEDYCKRII 318
>UniRef50_UPI0000E467CF Cluster: PREDICTED: hypothetical protein;
n=2; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 553
Score = 104 bits (250), Expect = 2e-21
Identities = 67/224 (29%), Positives = 108/224 (48%), Gaps = 10/224 (4%)
Frame = +3
Query: 39 FKEQGQALDKAARKDVKVLVVGN-PANTNALICSKYAPSIPKENFTAMTRLDQNRAQSQL 215
F G+ L++ A +DVKVL+ G N +AL+ AP I ++N RL +NRA++ +
Sbjct: 232 FALYGRILNQYAEQDVKVLIGGRGKLNFSALMLKHNAPRIARQNIIITPRLQENRAKAAI 291
Query: 216 AAKIGVPVKDVKRVIIWGNHSSTQFPDASNA------VAIVGGA--QKSVSEIINDDAYL 371
A KI V V +IIWGN D S A AI G + + V+E+++D+ +L
Sbjct: 292 ARKINVNTAGVADLIIWGNIGGITHFDISQARVYKYEGAIWGPSSFSRPVTEVVHDEKWL 351
Query: 372 KGAFVTTVQKRGAAVIXXXXXXXXXXXXXXXXDHMRDWFLGTEDRWV-SMGVVSDGSYGT 548
+ + +Q A+ + W+ G+ D+ + S+GV SDG Y
Sbjct: 352 QTEYPQLLQNHPDALATMLNHKVAMSEAHALTSILTHWYNGSPDKEIFSLGVYSDGWYDL 411
Query: 549 PRDVVYSFPVTVTNGKWKIVEGLTISDFARQMLDATGKELVEXK 680
P D+ +S PV G W++V+ ++ R LD EL+ +
Sbjct: 412 PVDIFFSLPVKFQKGAWEVVQDRQVTTEIRAQLDQITNELIHER 455
>UniRef50_UPI000065D9FE Cluster: malate dehydrogenase 1B, NAD
(soluble); n=1; Takifugu rubripes|Rep: malate
dehydrogenase 1B, NAD (soluble) - Takifugu rubripes
Length = 441
Score = 88.2 bits (209), Expect = 2e-16
Identities = 60/205 (29%), Positives = 93/205 (45%), Gaps = 10/205 (4%)
Frame = +3
Query: 39 FKEQGQALDKAARKDVKVLVVGNP-ANTNALICSKYAPSIPKENFTAMTRLDQNRAQSQL 215
++E G+ +D +K+VKV+V G N + Y SI A+ +N A++ +
Sbjct: 228 YREYGRLIDTQTKKEVKVIVSGESFVNLRCSLLLDYTHSIHSHQIVALATQLENEARAIV 287
Query: 216 AAKIGVPVKDVKRVIIWGNHSSTQFPDASNA-VAIVGGAQKS-------VSEIINDDAYL 371
A K+ V DV+ VI+WGN S + + D V G K IIND ++
Sbjct: 288 AKKLNVRPADVRDVIVWGNISGSFYVDLQKTKVFNYDGPVKGPEFFSLPAQNIINDRTWI 347
Query: 372 KGAFVTTVQKRGAAVIXXXXXXXXXXXXXXXXDHMRDWF-LGTEDRWVSMGVVSDGSYGT 548
+ F V+ R AAV+ ++ W LG + S+GV+ G +
Sbjct: 348 ETDFQELVRSRRAAVVSRMNRTTAMSCSHGILTVLKAWNGLGAGNEVFSLGVLCSGYHDL 407
Query: 549 PRDVVYSFPVTVTNGKWKIVEGLTI 623
P VV S P+T T+GKW + +TI
Sbjct: 408 PDGVVLSVPLTFTDGKWSALSDVTI 432
>UniRef50_Q5I0G3 Cluster: Malate dehydrogenase 1B; n=21;
Amniota|Rep: Malate dehydrogenase 1B - Homo sapiens
(Human)
Length = 518
Score = 81.0 bits (191), Expect = 3e-14
Identities = 61/235 (25%), Positives = 106/235 (45%), Gaps = 10/235 (4%)
Frame = +3
Query: 18 LAANVRIFKEQGQALDKAARKDVKVLVVGNP-ANTNALICSKYAPSIPKENFTAMTRLDQ 194
L + V + + G ++K A + V+V+V G N ++ +YAP I N A+ +
Sbjct: 229 LRSRVPLCRLYGYLIEKNAHESVRVIVGGRTFVNLKTVLLMRYAPRIA-HNIIAVALGVE 287
Query: 195 NRAQSQLAAKIGVPVKDVKRVIIWGNHSSTQFPDASNA------VAIVGGAQKS--VSEI 350
A++ LA K+ +K VIIWGN S + D AI G S V +
Sbjct: 288 GEAKAILARKLKTAPSYIKDVIIWGNISGNNYVDLRKTRVYRYESAIWGPLHYSRPVLNL 347
Query: 351 INDDAYLKGAFVTTVQKRGAAVIXXXXXXXXXXXXXXXXDHMRDWFLGTED-RWVSMGVV 527
I D ++K FV ++ + ++ W+ G+ VS+G++
Sbjct: 348 IFDSEWVKREFVAILKN----LTTTGRQFGGILAAHSIATTLKYWYHGSPPGEIVSLGIL 403
Query: 528 SDGSYGTPRDVVYSFPVTVTNGKWKIVEGLTISDFARQMLDATGKELVEXKQEAL 692
S+G +G P+ +V+S PV NG W ++ L + + Q++ +L++ K AL
Sbjct: 404 SEGQFGIPKGIVFSMPVKFENGTWVVLTDLKDVEISEQIMTRMTSDLIQEKLVAL 458
>UniRef50_UPI0000F2DF6E Cluster: PREDICTED: similar to Malate
dehydrogenase 1B, NAD (soluble); n=1; Monodelphis
domestica|Rep: PREDICTED: similar to Malate dehydrogenase
1B, NAD (soluble) - Monodelphis domestica
Length = 655
Score = 69.3 bits (162), Expect = 8e-11
Identities = 58/224 (25%), Positives = 97/224 (43%), Gaps = 10/224 (4%)
Frame = +3
Query: 51 GQALDKAARKDVKVLVVGNP-ANTNALICSKYAPSIPKENFTAMTRLDQNRAQSQLAAKI 227
G +DK A ++VKV+V G N + ++ PS+ N A+ + +N A++ LA K+
Sbjct: 374 GSLIDKNANENVKVIVAGKTFLNLTTSLIIQHTPSVNPRNIIAVAMIVENEAKAMLARKL 433
Query: 228 GVPVKDVKRVIIWGNHSSTQFPDASNA------VAIVGGAQKS--VSEIINDDAYLKGAF 383
VK VIIWGN + ++ D A AI G S + ++I D +++ F
Sbjct: 434 KTLPSYVKDVIIWGNITGFRYIDLKKAKIFKYNSAIWGPPNYSRFLLQLIFDSEWIRKEF 493
Query: 384 VTTVQKRGAAVIXXXXXXXXXXXXXXXXDHMRDWFLGT-EDRWVSMGVVSDGSYGTPRDV 560
V ++ A + WF + + S+G+ S+G +G P +
Sbjct: 494 VASLN----AWSLKEHFQKAIPSAHCIATMLTFWFHDSPPGEFFSVGIRSEGEFGMPEGM 549
Query: 561 VYSFPVTVTNGKWKIVEGLTISDFARQMLDATGKELVEXKQEAL 692
V S P NG W + L S+ D + + + +QE L
Sbjct: 550 VISMPAQCQNGIWTVPTDLIESELTE---DVRNRIIHDLQQEQL 590
>UniRef50_Q53TK9 Cluster: Malate dehydrogenase; n=3; Eutheria|Rep:
Malate dehydrogenase - Homo sapiens (Human)
Length = 283
Score = 51.6 bits (118), Expect = 2e-05
Identities = 22/74 (29%), Positives = 43/74 (58%), Gaps = 1/74 (1%)
Frame = +3
Query: 474 MRDWFLGTED-RWVSMGVVSDGSYGTPRDVVYSFPVTVTNGKWKIVEGLTISDFARQMLD 650
++ W+ G+ VS+G++S+G +G P+ +V+S PV NG W ++ L + + Q++
Sbjct: 172 LKYWYHGSPPGEIVSLGILSEGQFGIPKGIVFSMPVKFENGTWVVLTDLKDVEISEQIMT 231
Query: 651 ATGKELVEXKQEAL 692
+L++ K AL
Sbjct: 232 RMTSDLIQEKLVAL 245
>UniRef50_UPI0000DB7CA5 Cluster: PREDICTED: similar to
tetratricopeptide repeat domain 21B; n=1; Apis
mellifera|Rep: PREDICTED: similar to tetratricopeptide
repeat domain 21B - Apis mellifera
Length = 1491
Score = 48.0 bits (109), Expect = 2e-04
Identities = 36/147 (24%), Positives = 65/147 (44%), Gaps = 2/147 (1%)
Frame = +3
Query: 213 LAAKIGVPVKDVKRVIIWGNHSSTQFPDASNAVAIVGGAQKSVSEI-INDDAYLKGAFVT 389
+AA+ +VK +IIWG++ S FPD G K +I I +D +
Sbjct: 1332 IAAQANCLPTEVKNIIIWGSNGSYCFPDCRYLYLTNGKPLKDSIKIWIYNDL---PRIIR 1388
Query: 390 TVQKRGAAVIXXXXXXXXXXXXXXXXDHMRDWFLGT-EDRWVSMGVVSDGSYGTPRDVVY 566
+ R + +H + + GT E+ W SMGV+SD SY + +
Sbjct: 1389 STYNRACLI---------NSIAYALAEHCKILWNGTPENEWTSMGVLSDLSYSIQSGIFF 1439
Query: 567 SFPVTVTNGKWKIVEGLTISDFARQML 647
SFPV + + +I++ + ++ ++ +
Sbjct: 1440 SFPVICKDKQCEIIKDFELDEYVKKYI 1466
>UniRef50_A7I5J9 Cluster: L-lactate dehydrogenase precursor; n=1;
Candidatus Methanoregula boonei 6A8|Rep: L-lactate
dehydrogenase precursor - Methanoregula boonei (strain
6A8)
Length = 332
Score = 43.6 bits (98), Expect = 0.005
Identities = 28/93 (30%), Positives = 42/93 (45%)
Frame = +3
Query: 15 LLAANVRIFKEQGQALDKAARKDVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLDQ 194
L N RI + + A D K+++V NP + + KY+ P + F T LD
Sbjct: 94 LALGNARIIAPMARTIGTIA-PDTKIIMVTNPVDVMTCVALKYSGLKPNQVFGLGTHLDS 152
Query: 195 NRAQSQLAAKIGVPVKDVKRVIIWGNHSSTQFP 293
R +S +A+ V V +V II G H + P
Sbjct: 153 MRLKSLIASYFKVHVSEVHTRII-GEHGDSMVP 184
>UniRef50_A2SSY4 Cluster: L-lactate dehydrogenase; n=3;
Methanomicrobiales|Rep: L-lactate dehydrogenase -
Methanocorpusculum labreanum (strain ATCC 43576 / DSM
4855 / Z)
Length = 319
Score = 43.6 bits (98), Expect = 0.005
Identities = 34/106 (32%), Positives = 48/106 (45%)
Frame = +3
Query: 15 LLAANVRIFKEQGQALDKAARKDVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLDQ 194
L N RI K + + + A + + +LVV NP + + KY+ +P F T LD
Sbjct: 94 LALENARIVKVFAEQVGRMAPEAI-LLVVTNPVDIMTTVALKYSGMMPHRVFGLGTHLDS 152
Query: 195 NRAQSQLAAKIGVPVKDVKRVIIWGNHSSTQFPDASNAVAIVGGAQ 332
R ++ LA V V ++ II G H T P S VGG Q
Sbjct: 153 MRLKACLAEFFNVHVSEIHTRII-GEHGDTMVPMWS--ATTVGGIQ 195
>UniRef50_Q2S4R2 Cluster: L-lactate dehydrogenase; n=1; Salinibacter
ruber DSM 13855|Rep: L-lactate dehydrogenase -
Salinibacter ruber (strain DSM 13855)
Length = 316
Score = 43.6 bits (98), Expect = 0.005
Identities = 59/226 (26%), Positives = 89/226 (39%), Gaps = 2/226 (0%)
Frame = +3
Query: 15 LLAANVRIFKEQGQALDKAARKDVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLDQ 194
LL N IF+E LDK A + V V NP + IC + + + T LD
Sbjct: 93 LLQRNAEIFREIIIQLDKHAPNAILV-VATNPVDVLTYICQELSSRPNRRILGTGTLLDT 151
Query: 195 NRAQSQLAAKIGVPVKDVKRVIIWGNHSSTQFPDASNAVAIVGGAQKSVSEIINDDAYLK 374
R ++ L GV + V I+ G H ++ P SNA +GG QK E + + +
Sbjct: 152 ARFRALLGRHYGVDPRSVHAYIL-GEHGDSEVPIWSNAT--IGG-QKIRGETVLGKEWEE 207
Query: 375 GAFVTTV-QKRGAAVIXXXXXXXXXXXXXXXXDHMRDWFLGTEDRWVSMGVVSDGSYGTP 551
A + Q R AA + L + + + DG+YG
Sbjct: 208 EAMQSIFEQARDAAYEIIDRKGHTDTAIGLVIARIVRAVLEDQQNVLPVSTRPDGAYGID 267
Query: 552 RDVVYSFPVTV-TNGKWKIVEGLTISDFARQMLDATGKELVEXKQE 686
DV S P V G K V+ +SD R+ L + + L + + +
Sbjct: 268 -DVCLSVPCVVGLEGMEKRVDP-GLSDEEREALRDSARALRDSRAD 311
>UniRef50_A1U9V0 Cluster: Lactate/malate dehydrogenase; n=6;
Actinomycetales|Rep: Lactate/malate dehydrogenase -
Mycobacterium sp. (strain KMS)
Length = 329
Score = 43.2 bits (97), Expect = 0.006
Identities = 47/194 (24%), Positives = 77/194 (39%), Gaps = 1/194 (0%)
Frame = +3
Query: 15 LLAANVRIFKEQGQALDKAARKDVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLDQ 194
L AANV + + L + + D V+ V NP + S + P + F T LD
Sbjct: 107 LAAANVAMAQTLTPQLLEHS-PDAVVIFVTNPVDVVTYAASSVVDAQPGQIFGTGTVLDS 165
Query: 195 NRAQSQLAAKIGVPVKDVKRVIIWGNHSSTQFPDASN-AVAIVGGAQKSVSEIINDDAYL 371
+R + +A + + V +V ++I G H ++ P S ++ VG V + D
Sbjct: 166 SRFRYLVAQRAAIAVGNVHALVI-GEHGDSEIPLWSTLSIGGVGADAYRVDGRLVFDEPT 224
Query: 372 KGAFVTTVQKRGAAVIXXXXXXXXXXXXXXXXDHMRDWFLGTEDRWVSMGVVSDGSYGTP 551
+ A T V +I + + LG + R + + V DG+YG
Sbjct: 225 RTAVATDVVNAAYEIIAGKGATNLAIGLATA--RVVEAVLGDQHRVLPVSTVQDGAYGI- 281
Query: 552 RDVVYSFPVTVTNG 593
V S P V+ G
Sbjct: 282 TGVALSLPTVVSAG 295
>UniRef50_Q7UY63 Cluster: L-lactate/malate dehydrogenase; n=2;
Planctomycetaceae|Rep: L-lactate/malate dehydrogenase -
Rhodopirellula baltica
Length = 304
Score = 39.9 bits (89), Expect = 0.058
Identities = 28/100 (28%), Positives = 51/100 (51%)
Frame = +3
Query: 27 NVRIFKEQGQALDKAARKDVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLDQNRAQ 206
N+ I ++ L KA+ + V++V NP + A + PK T +D R +
Sbjct: 94 NMPILRDWMPGLAKASPNAI-VVMVSNPVDALAYETIRLTGFDPKRVIGTGTLVDSIRYR 152
Query: 207 SQLAAKIGVPVKDVKRVIIWGNHSSTQFPDASNAVAIVGG 326
+ L+ ++ + +D+ R I G H TQF A++++A+ GG
Sbjct: 153 ALLSTELKIHAQDI-RAYILGEHGDTQF--AASSIAMTGG 189
>UniRef50_Q5CVB2 Cluster: DHHC family palmitoyl transferase with a
signal peptide and 4 transmembrane domains; n=2;
Cryptosporidium|Rep: DHHC family palmitoyl transferase
with a signal peptide and 4 transmembrane domains -
Cryptosporidium parvum Iowa II
Length = 562
Score = 34.7 bits (76), Expect = 2.2
Identities = 24/75 (32%), Positives = 33/75 (44%), Gaps = 4/75 (5%)
Frame = +2
Query: 371 ERRICNNGSKTWCCRYCRQENVI-CSFC--C*SCIRPHERLVPWH*RQMG*HGSC-FRWI 538
E ++ NG + C YCR + C C CIR H+ PW +G + C F W+
Sbjct: 374 EGKMYQNGVRLRFCDYCRMYQPLRTKHCTSCERCIRTHDHHCPWLGVCIGEYNRCKFWWL 433
Query: 539 LWYSA*CCIFIPCYC 583
CI+I YC
Sbjct: 434 SLVQFPECIWI-LYC 447
>UniRef50_UPI00006D0DE8 Cluster: Latrophilin/CL-1-like GPS domain
containing protein; n=1; Tetrahymena thermophila
SB210|Rep: Latrophilin/CL-1-like GPS domain containing
protein - Tetrahymena thermophila SB210
Length = 5230
Score = 34.3 bits (75), Expect = 2.9
Identities = 15/22 (68%), Positives = 16/22 (72%), Gaps = 1/22 (4%)
Frame = -3
Query: 522 LPC*PICLQC-QGTNLSCGLMQ 460
LPC P+CLQC TNLSC L Q
Sbjct: 2873 LPCNPLCLQCTDQTNLSCSLCQ 2894
>UniRef50_Q8I8U4 Cluster: Lactate dehydrogenase; n=3;
Eimeriorina|Rep: Lactate dehydrogenase - Eimeria tenella
Length = 331
Score = 34.3 bits (75), Expect = 2.9
Identities = 27/94 (28%), Positives = 44/94 (46%), Gaps = 1/94 (1%)
Frame = +3
Query: 15 LLAANVRIFKEQGQALDKAARKDVKVLVVGNPANTNALICSKYAPSIPKENFTAMTR-LD 191
LL NV+I +E G A+ K V+ + NP + + + A +P M LD
Sbjct: 103 LLPVNVKILREVGAAI-KQFCPHAFVINITNPLDV-MVAALREAAGLPAARVCGMAGVLD 160
Query: 192 QNRAQSQLAAKIGVPVKDVKRVIIWGNHSSTQFP 293
R + LA ++GV +DV+ +++ G H P
Sbjct: 161 SARFRRLLADRLGVSPRDVQAMVL-GVHGDNMVP 193
>UniRef50_A0BUG0 Cluster: Chromosome undetermined scaffold_129,
whole genome shotgun sequence; n=1; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_129,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 283
Score = 33.9 bits (74), Expect = 3.8
Identities = 16/32 (50%), Positives = 22/32 (68%)
Frame = +3
Query: 594 KWKIVEGLTISDFARQMLDATGKELVEXKQEA 689
K K+VEGL + F + M+D T KEL+E K+ A
Sbjct: 7 KVKVVEGLKLDQFLQCMIDKTLKELLEEKEMA 38
>UniRef50_Q1ZR52 Cluster: Beta-lactamase; n=2; Vibrionaceae|Rep:
Beta-lactamase - Vibrio angustum S14
Length = 318
Score = 33.5 bits (73), Expect = 5.0
Identities = 18/44 (40%), Positives = 26/44 (59%)
Frame = +3
Query: 162 ENFTAMTRLDQNRAQSQLAAKIGVPVKDVKRVIIWGNHSSTQFP 293
EN T + ++ A+ QL A+IGV V D K ++G HS +FP
Sbjct: 54 ENITVNSAIEH--AEKQLGARIGVSVFDGKGKQLFGYHSDQRFP 95
>UniRef50_Q0RYH4 Cluster: Putative uncharacterized protein; n=1;
Rhodococcus sp. RHA1|Rep: Putative uncharacterized
protein - Rhodococcus sp. (strain RHA1)
Length = 362
Score = 33.5 bits (73), Expect = 5.0
Identities = 17/49 (34%), Positives = 28/49 (57%)
Frame = -2
Query: 391 VVTNAPFKYASSLIISETDF*APPTIATAFEASGNWVDEWFPQMITLLT 245
VV P +S+ +I + ++ AP IA + E +W+ +FPQ+I LT
Sbjct: 126 VVIKVPRNVSSNALI-DAEWAAPTEIAASAEGGNDWLRAYFPQLIDHLT 173
>UniRef50_Q0U265 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 1081
Score = 33.1 bits (72), Expect = 6.6
Identities = 17/51 (33%), Positives = 26/51 (50%)
Frame = -2
Query: 625 EIVRPSTIFHFPLVTVTGNEYTTSRGVP*DPSETTPMLTHLSSVPRNQSLM 473
E RPS+ TGNE ++ + P P + TH+ S+PR++S M
Sbjct: 966 EDARPSSRRRRLANRATGNERSSEKNTPARPKRVRRLSTHIMSLPRSESSM 1016
>UniRef50_A4QXM2 Cluster: Putative uncharacterized protein; n=1;
Magnaporthe grisea|Rep: Putative uncharacterized protein
- Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 323
Score = 33.1 bits (72), Expect = 6.6
Identities = 23/93 (24%), Positives = 39/93 (41%)
Frame = +3
Query: 15 LLAANVRIFKEQGQALDKAARKDVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLDQ 194
L +N IFKE + + A D +LV NP + K++ + T LD
Sbjct: 100 LAQSNWGIFKEIVPKVVQHASPDALLLVSANPVDVMTYAAVKFSGFPAHSVIGSGTSLDS 159
Query: 195 NRAQSQLAAKIGVPVKDVKRVIIWGNHSSTQFP 293
R +L + + + + V+I G H ++ P
Sbjct: 160 ARFAGELGKHLNIDPRSLHAVVI-GEHGESELP 191
>UniRef50_O26290 Cluster: Malate dehydrogenase; n=2;
Methanobacteriaceae|Rep: Malate dehydrogenase -
Methanobacterium thermoautotrophicum
Length = 325
Score = 33.1 bits (72), Expect = 6.6
Identities = 23/89 (25%), Positives = 38/89 (42%)
Frame = +3
Query: 27 NVRIFKEQGQALDKAARKDVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLDQNRAQ 206
N RI + + + + A + +LVV NP + + +Y+ P F LD R +
Sbjct: 97 NGRIVADYARQIARFAPDSI-ILVVTNPVDVMTYVALRYSGFHPSRVFGLGNHLDSLRLK 155
Query: 207 SQLAAKIGVPVKDVKRVIIWGNHSSTQFP 293
+ +A V V +V +I G H P
Sbjct: 156 NYMARHFNVHVSEVHTRVI-GQHGPYMVP 183
>UniRef50_Q7NG49 Cluster: L-lactate dehydrogenase; n=4;
Cyanobacteria|Rep: L-lactate dehydrogenase - Gloeobacter
violaceus
Length = 330
Score = 33.1 bits (72), Expect = 6.6
Identities = 28/99 (28%), Positives = 45/99 (45%), Gaps = 1/99 (1%)
Frame = +3
Query: 15 LLAANVRIFKEQ-GQALDKAARKDVKVLVVGNPANTNALICSKYAPSIPKENFTAMTRLD 191
L+ NV IF+ G+ ++ + +LVV NP + + K A P + T LD
Sbjct: 108 LVQRNVEIFRGLIGEIMEHCP--NAILLVVSNPVDVMTYVAMKLAGLPPSRVIGSGTVLD 165
Query: 192 QNRAQSQLAAKIGVPVKDVKRVIIWGNHSSTQFPDASNA 308
R + LA ++ V + + II G H ++ P S A
Sbjct: 166 TARFRYLLAERLRVDPRSLHAYII-GEHGDSEVPVWSRA 203
>UniRef50_Q2SQM3 Cluster: Putative uncharacterized protein; n=1;
Hahella chejuensis KCTC 2396|Rep: Putative
uncharacterized protein - Hahella chejuensis (strain
KCTC 2396)
Length = 586
Score = 32.7 bits (71), Expect = 8.8
Identities = 13/36 (36%), Positives = 21/36 (58%)
Frame = -2
Query: 316 IATAFEASGNWVDEWFPQMITLLTSLTGTPILAASW 209
I+ E +G +++WF Q +T S G P+LA +W
Sbjct: 487 ISPKVELNGRSMEDWFKQTVTENLSYLGEPLLAQNW 522
>UniRef50_Q54DK4 Cluster: Putative uncharacterized protein ak1; n=1;
Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein ak1 - Dictyostelium discoideum
AX4
Length = 1352
Score = 32.7 bits (71), Expect = 8.8
Identities = 21/65 (32%), Positives = 29/65 (44%)
Frame = -3
Query: 561 QHHAEYHKIHLKQLPC*PICLQCQGTNLSCGLMQL*QQKEQMTFSWRQ*RQHHVFEPLLQ 382
QHH+ K+HL +P LQ Q L L Q QQ++Q +Q +Q + P
Sbjct: 378 QHHSSDFKVHLIDIPTTQQQLQQQQLQLQQQLQQQLQQQQQQQQQQQQQQQSPISNPFTS 437
Query: 381 MRLSN 367
SN
Sbjct: 438 NNNSN 442
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 717,466,688
Number of Sequences: 1657284
Number of extensions: 15296777
Number of successful extensions: 41046
Number of sequences better than 10.0: 51
Number of HSP's better than 10.0 without gapping: 39135
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 40966
length of database: 575,637,011
effective HSP length: 98
effective length of database: 413,223,179
effective search space used: 54545459628
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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