Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P17_F_I18
(792 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
Y15924-1|CAA75882.1| 367|Homo sapiens cystinosin protein. 96 1e-19
CR542058-1|CAG46855.1| 367|Homo sapiens CTNS protein. 96 1e-19
BC032850-1|AAH32850.1| 400|Homo sapiens cystinosis, nephropathi... 96 1e-19
AJ222967-1|CAA11021.1| 367|Homo sapiens cystinosin protein. 96 1e-19
AF168787-2|AAF43102.1| 367|Homo sapiens CTNS protein. 96 1e-19
AK172745-1|BAD18732.1| 180|Homo sapiens protein ( Homo sapiens ... 44 6e-04
BC015324-1|AAH15324.1| 226|Homo sapiens PQ loop repeat containi... 42 0.003
AL035413-7|CAI22229.1| 291|Homo sapiens PQ loop repeat containi... 42 0.003
AL035413-3|CAM12847.1| 226|Homo sapiens PQ loop repeat containi... 42 0.003
AK130175-1|BAC85298.1| 291|Homo sapiens protein ( Homo sapiens ... 42 0.003
AK130171-1|BAC85296.1| 291|Homo sapiens protein ( Homo sapiens ... 42 0.003
AK000327-1|BAA91088.1| 226|Homo sapiens protein ( Homo sapiens ... 42 0.003
BC111738-1|AAI11739.1| 885|Homo sapiens hypothetical protein LO... 31 3.6
BC111696-1|AAI11697.1| 885|Homo sapiens hypothetical protein LO... 31 3.6
AK126338-1|BAC86529.1| 885|Homo sapiens protein ( Homo sapiens ... 31 3.6
>Y15924-1|CAA75882.1| 367|Homo sapiens cystinosin protein.
Length = 367
Score = 95.9 bits (228), Expect = 1e-19
Identities = 39/68 (57%), Positives = 55/68 (80%)
Frame = +2
Query: 584 LRITVMHSNEINIISYIMGWIYFAAWSVSFYPQIYINFKRKSVXGLNFDFLALNIMGFTM 763
+R V+ S+ I+II+ ++GWIYF AWS+SFYPQ+ +N++RKSV GL+FDF+ALN+ GF
Sbjct: 113 IRFLVIRSSAISIINQVIGWIYFVAWSISFYPQVIMNWRRKSVIGLSFDFVALNLTGFVA 172
Query: 764 YSLXNCGL 787
YS+ N GL
Sbjct: 173 YSVFNIGL 180
Score = 31.1 bits (67), Expect = 4.8
Identities = 24/98 (24%), Positives = 48/98 (48%), Gaps = 5/98 (5%)
Frame = +2
Query: 476 TVVISYDICAYGKSPGHSEVTFNVTPPGFVNLDTVYLRITVMHSNEINIISYIM-----G 640
T++I C Y + G V++ GF+ L ++ +T++ + + +I+++
Sbjct: 216 TLIIIVQCCLYER--GGQRVSWPAI--GFLVLAWLFAFVTMIVA-AVGVITWLQFLFCFS 270
Query: 641 WIYFAAWSVSFYPQIYINFKRKSVXGLNFDFLALNIMG 754
+I A V ++PQ Y+NF KS G + + L+ G
Sbjct: 271 YIKLAVTLVKYFPQAYMNFYYKSTEGWSIGNVLLDFTG 308
>CR542058-1|CAG46855.1| 367|Homo sapiens CTNS protein.
Length = 367
Score = 95.9 bits (228), Expect = 1e-19
Identities = 39/68 (57%), Positives = 55/68 (80%)
Frame = +2
Query: 584 LRITVMHSNEINIISYIMGWIYFAAWSVSFYPQIYINFKRKSVXGLNFDFLALNIMGFTM 763
+R V+ S+ I+II+ ++GWIYF AWS+SFYPQ+ +N++RKSV GL+FDF+ALN+ GF
Sbjct: 113 IRFLVIRSSAISIINQVIGWIYFVAWSISFYPQVIMNWRRKSVIGLSFDFVALNLTGFVA 172
Query: 764 YSLXNCGL 787
YS+ N GL
Sbjct: 173 YSVFNIGL 180
>BC032850-1|AAH32850.1| 400|Homo sapiens cystinosis, nephropathic
protein.
Length = 400
Score = 95.9 bits (228), Expect = 1e-19
Identities = 39/68 (57%), Positives = 55/68 (80%)
Frame = +2
Query: 584 LRITVMHSNEINIISYIMGWIYFAAWSVSFYPQIYINFKRKSVXGLNFDFLALNIMGFTM 763
+R V+ S+ I+II+ ++GWIYF AWS+SFYPQ+ +N++RKSV GL+FDF+ALN+ GF
Sbjct: 113 IRFLVIRSSAISIINQVIGWIYFVAWSISFYPQVIMNWRRKSVIGLSFDFVALNLTGFVA 172
Query: 764 YSLXNCGL 787
YS+ N GL
Sbjct: 173 YSVFNIGL 180
Score = 31.1 bits (67), Expect = 4.8
Identities = 24/98 (24%), Positives = 48/98 (48%), Gaps = 5/98 (5%)
Frame = +2
Query: 476 TVVISYDICAYGKSPGHSEVTFNVTPPGFVNLDTVYLRITVMHSNEINIISYIM-----G 640
T++I C Y + G V++ GF+ L ++ +T++ + + +I+++
Sbjct: 216 TLIIIVQCCLYER--GGQRVSWPAI--GFLVLAWLFAFVTMIVA-AVGVITWLQFLFCFS 270
Query: 641 WIYFAAWSVSFYPQIYINFKRKSVXGLNFDFLALNIMG 754
+I A V ++PQ Y+NF KS G + + L+ G
Sbjct: 271 YIKLAVTLVKYFPQAYMNFYYKSTEGWSIGNVLLDFTG 308
>AJ222967-1|CAA11021.1| 367|Homo sapiens cystinosin protein.
Length = 367
Score = 95.9 bits (228), Expect = 1e-19
Identities = 39/68 (57%), Positives = 55/68 (80%)
Frame = +2
Query: 584 LRITVMHSNEINIISYIMGWIYFAAWSVSFYPQIYINFKRKSVXGLNFDFLALNIMGFTM 763
+R V+ S+ I+II+ ++GWIYF AWS+SFYPQ+ +N++RKSV GL+FDF+ALN+ GF
Sbjct: 113 IRFLVIRSSAISIINQVIGWIYFVAWSISFYPQVIMNWRRKSVIGLSFDFVALNLTGFVA 172
Query: 764 YSLXNCGL 787
YS+ N GL
Sbjct: 173 YSVFNIGL 180
Score = 31.1 bits (67), Expect = 4.8
Identities = 24/98 (24%), Positives = 48/98 (48%), Gaps = 5/98 (5%)
Frame = +2
Query: 476 TVVISYDICAYGKSPGHSEVTFNVTPPGFVNLDTVYLRITVMHSNEINIISYIM-----G 640
T++I C Y + G V++ GF+ L ++ +T++ + + +I+++
Sbjct: 216 TLIIIVQCCLYER--GGQRVSWPAI--GFLVLAWLFAFVTMIVA-AVGVITWLQFLFCFS 270
Query: 641 WIYFAAWSVSFYPQIYINFKRKSVXGLNFDFLALNIMG 754
+I A V ++PQ Y+NF KS G + + L+ G
Sbjct: 271 YIKLAVTLVKYFPQAYMNFYYKSTEGWSIGNVLLDFTG 308
>AF168787-2|AAF43102.1| 367|Homo sapiens CTNS protein.
Length = 367
Score = 95.9 bits (228), Expect = 1e-19
Identities = 39/68 (57%), Positives = 55/68 (80%)
Frame = +2
Query: 584 LRITVMHSNEINIISYIMGWIYFAAWSVSFYPQIYINFKRKSVXGLNFDFLALNIMGFTM 763
+R V+ S+ I+II+ ++GWIYF AWS+SFYPQ+ +N++RKSV GL+FDF+ALN+ GF
Sbjct: 113 IRFLVIRSSAISIINQVIGWIYFVAWSISFYPQVIMNWRRKSVIGLSFDFVALNLTGFVA 172
Query: 764 YSLXNCGL 787
YS+ N GL
Sbjct: 173 YSVFNIGL 180
Score = 31.1 bits (67), Expect = 4.8
Identities = 24/98 (24%), Positives = 48/98 (48%), Gaps = 5/98 (5%)
Frame = +2
Query: 476 TVVISYDICAYGKSPGHSEVTFNVTPPGFVNLDTVYLRITVMHSNEINIISYIM-----G 640
T++I C Y + G V++ GF+ L ++ +T++ + + +I+++
Sbjct: 216 TLIIIVQCCLYER--GGQRVSWPAI--GFLVLAWLFAFVTMIVA-AVGVITWLQFLFCFS 270
Query: 641 WIYFAAWSVSFYPQIYINFKRKSVXGLNFDFLALNIMG 754
+I A V ++PQ Y+NF KS G + + L+ G
Sbjct: 271 YIKLAVTLVKYFPQAYMNFYYKSTEGWSIGNVLLDFTG 308
>AK172745-1|BAD18732.1| 180|Homo sapiens protein ( Homo sapiens
cDNA FLJ23906 fis, clone ADSE01759. ).
Length = 180
Score = 44.0 bits (99), Expect = 6e-04
Identities = 19/51 (37%), Positives = 32/51 (62%)
Frame = +2
Query: 620 IISYIMGWIYFAAWSVSFYPQIYINFKRKSVXGLNFDFLALNIMGFTMYSL 772
+I +++G I+ + +S PQI NF RKS G+++ AL ++G T+Y L
Sbjct: 71 VIGFVIGSIFSVLYLLSRLPQIRTNFLRKSTQGISYSLFALVMLGNTLYGL 121
>BC015324-1|AAH15324.1| 226|Homo sapiens PQ loop repeat containing
2 protein.
Length = 226
Score = 41.9 bits (94), Expect = 0.003
Identities = 19/51 (37%), Positives = 31/51 (60%)
Frame = +2
Query: 620 IISYIMGWIYFAAWSVSFYPQIYINFKRKSVXGLNFDFLALNIMGFTMYSL 772
+I +++G I + +S PQI NF RKS G+++ AL ++G T+Y L
Sbjct: 117 VIGFVIGSISSVLYLLSRLPQIRTNFLRKSTQGISYSLFALVMLGNTLYGL 167
>AL035413-7|CAI22229.1| 291|Homo sapiens PQ loop repeat containing
2 protein.
Length = 291
Score = 41.9 bits (94), Expect = 0.003
Identities = 19/51 (37%), Positives = 31/51 (60%)
Frame = +2
Query: 620 IISYIMGWIYFAAWSVSFYPQIYINFKRKSVXGLNFDFLALNIMGFTMYSL 772
+I +++G I + +S PQI NF RKS G+++ AL ++G T+Y L
Sbjct: 182 VIGFVIGSISSVLYLLSRLPQIRTNFLRKSTQGISYSLFALVMLGNTLYGL 232
>AL035413-3|CAM12847.1| 226|Homo sapiens PQ loop repeat containing
2 protein.
Length = 226
Score = 41.9 bits (94), Expect = 0.003
Identities = 19/51 (37%), Positives = 31/51 (60%)
Frame = +2
Query: 620 IISYIMGWIYFAAWSVSFYPQIYINFKRKSVXGLNFDFLALNIMGFTMYSL 772
+I +++G I + +S PQI NF RKS G+++ AL ++G T+Y L
Sbjct: 117 VIGFVIGSISSVLYLLSRLPQIRTNFLRKSTQGISYSLFALVMLGNTLYGL 167
>AK130175-1|BAC85298.1| 291|Homo sapiens protein ( Homo sapiens
cDNA FLJ26665 fis, clone MPG02687. ).
Length = 291
Score = 41.9 bits (94), Expect = 0.003
Identities = 19/51 (37%), Positives = 31/51 (60%)
Frame = +2
Query: 620 IISYIMGWIYFAAWSVSFYPQIYINFKRKSVXGLNFDFLALNIMGFTMYSL 772
+I +++G I + +S PQI NF RKS G+++ AL ++G T+Y L
Sbjct: 182 VIGFVIGSISSVLYLLSRLPQIRTNFLRKSTQGISYSLFALVMLGNTLYGL 232
>AK130171-1|BAC85296.1| 291|Homo sapiens protein ( Homo sapiens
cDNA FLJ26661 fis, clone MPG01974. ).
Length = 291
Score = 41.9 bits (94), Expect = 0.003
Identities = 19/51 (37%), Positives = 31/51 (60%)
Frame = +2
Query: 620 IISYIMGWIYFAAWSVSFYPQIYINFKRKSVXGLNFDFLALNIMGFTMYSL 772
+I +++G I + +S PQI NF RKS G+++ AL ++G T+Y L
Sbjct: 182 VIGFVIGSISSVLYLLSRLPQIRTNFLRKSTQGISYSLFALVMLGNTLYGL 232
>AK000327-1|BAA91088.1| 226|Homo sapiens protein ( Homo sapiens
cDNA FLJ20320 fis, clone HEP08923. ).
Length = 226
Score = 41.9 bits (94), Expect = 0.003
Identities = 19/51 (37%), Positives = 31/51 (60%)
Frame = +2
Query: 620 IISYIMGWIYFAAWSVSFYPQIYINFKRKSVXGLNFDFLALNIMGFTMYSL 772
+I +++G I + +S PQI NF RKS G+++ AL ++G T+Y L
Sbjct: 117 VIGFVIGSISSVLYLLSRLPQIRTNFLRKSTQGISYSLFALVMLGNTLYGL 167
>BC111738-1|AAI11739.1| 885|Homo sapiens hypothetical protein
LOC222256 protein.
Length = 885
Score = 31.5 bits (68), Expect = 3.6
Identities = 18/40 (45%), Positives = 24/40 (60%), Gaps = 2/40 (5%)
Frame = -1
Query: 588 RRYTVSKLTKPGGVTLNVTSECPG--LFPYAHISYDITTV 475
R YTV + PG + N+T+E P FP +H+ Y ITTV
Sbjct: 241 RVYTVLEELSPGTIVANITAEDPDDEGFP-SHLLYSITTV 279
>BC111696-1|AAI11697.1| 885|Homo sapiens hypothetical protein
LOC222256 protein.
Length = 885
Score = 31.5 bits (68), Expect = 3.6
Identities = 18/40 (45%), Positives = 24/40 (60%), Gaps = 2/40 (5%)
Frame = -1
Query: 588 RRYTVSKLTKPGGVTLNVTSECPG--LFPYAHISYDITTV 475
R YTV + PG + N+T+E P FP +H+ Y ITTV
Sbjct: 241 RVYTVLEELSPGTIVANITAEDPDDEGFP-SHLLYSITTV 279
>AK126338-1|BAC86529.1| 885|Homo sapiens protein ( Homo sapiens
cDNA FLJ44366 fis, clone TRACH3008629, weakly similar
to Cadherin-related tumor suppressor precursor. ).
Length = 885
Score = 31.5 bits (68), Expect = 3.6
Identities = 18/40 (45%), Positives = 24/40 (60%), Gaps = 2/40 (5%)
Frame = -1
Query: 588 RRYTVSKLTKPGGVTLNVTSECPG--LFPYAHISYDITTV 475
R YTV + PG + N+T+E P FP +H+ Y ITTV
Sbjct: 241 RVYTVLEELSPGTIVANITAEDPDDEGFP-SHLLYSITTV 279
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 104,376,899
Number of Sequences: 237096
Number of extensions: 2279159
Number of successful extensions: 4205
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 4095
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4205
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 9701808132
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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