Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P17_F_I06
(802 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q17DR1 Cluster: Cystathionine beta-lyase; n=6; Coelomat... 308 8e-83
UniRef50_P32929 Cluster: Cystathionine gamma-lyase; n=38; cellul... 272 5e-72
UniRef50_Q8VCN5 Cluster: Cystathionine gamma-lyase; n=39; Eukary... 258 9e-68
UniRef50_Q23CV0 Cluster: Cystathionine beta-lyase; n=3; Oligohym... 229 6e-59
UniRef50_Q129P6 Cluster: Cystathionine gamma-synthase; n=11; cel... 225 1e-57
UniRef50_P24601 Cluster: Probable cystathionine gamma-synthase (... 223 4e-57
UniRef50_UPI0000F2BB70 Cluster: PREDICTED: similar to Chain A, C... 215 1e-54
UniRef50_Q74EL7 Cluster: Cystathionine beta-lyase; n=5; Bacteria... 205 9e-52
UniRef50_Q9EWF9 Cluster: Cystathionine gamma-synthase; n=6; Bact... 203 5e-51
UniRef50_P56069 Cluster: Cystathionine gamma-synthase (EC 2.5.1.... 202 6e-51
UniRef50_Q5L1M8 Cluster: Cystathionine beta-lyase; n=42; Bacteri... 202 8e-51
UniRef50_Q6N7A1 Cluster: Cystathionine gamma-lyase; n=52; cellul... 201 1e-50
UniRef50_Q97M10 Cluster: Cystathionine gamma-synthase; n=15; Bac... 200 2e-50
UniRef50_Q8KEI8 Cluster: Trans-sulfuration enzyme family protein... 197 2e-49
UniRef50_A6LPZ9 Cluster: Cystathionine gamma-synthase; n=4; Bact... 195 1e-48
UniRef50_Q1INQ0 Cluster: Cystathionine gamma-synthase; n=2; Bact... 194 3e-48
UniRef50_Q4A0K3 Cluster: Cystathionine gamma-synthase; n=4; Bact... 191 2e-47
UniRef50_Q838Z2 Cluster: Cystathionine beta-lyase; n=8; Bacteria... 191 2e-47
UniRef50_Q2IEA5 Cluster: Cystathionine gamma-synthase; n=1; Anae... 189 6e-47
UniRef50_Q49UL2 Cluster: Cystathionine beta-lyase cystathionine ... 185 1e-45
UniRef50_Q1IQD6 Cluster: Cystathionine gamma-synthase; n=2; Acid... 185 1e-45
UniRef50_A7HF96 Cluster: Cystathionine gamma-synthase; n=7; Bact... 183 4e-45
UniRef50_P46807 Cluster: Cystathionine gamma-synthase (EC 2.5.1.... 182 7e-45
UniRef50_A5E0C2 Cluster: Cystathionine gamma-lyase; n=6; cellula... 182 1e-44
UniRef50_Q8XNZ9 Cluster: Cystathionine gamma-synthase; n=7; Bact... 180 4e-44
UniRef50_P53780 Cluster: Cystathionine beta-lyase, chloroplast p... 173 4e-42
UniRef50_A7H124 Cluster: Methionine gamma-lyase; n=2; Campylobac... 171 2e-41
UniRef50_Q5MQ31 Cluster: L-methionine-gamma-lyase; n=3; Micrococ... 169 9e-41
UniRef50_A3HJ37 Cluster: Cystathionine gamma-lyase; n=7; Gammapr... 169 9e-41
UniRef50_Q38DH3 Cluster: Cystathione gamma lyase, putative; n=7;... 168 2e-40
UniRef50_A0LLP6 Cluster: Cystathionine gamma-synthase; n=1; Synt... 167 2e-40
UniRef50_Q8KNG3 Cluster: CalE6; n=2; Micromonosporaceae|Rep: Cal... 167 4e-40
UniRef50_A6X770 Cluster: Cystathionine gamma-synthase; n=1; Ochr... 162 1e-38
UniRef50_Q8R9N2 Cluster: Cystathionine beta-lyases/cystathionine... 161 1e-38
UniRef50_Q12L75 Cluster: Methionine gamma-lyase; n=1; Shewanella... 161 1e-38
UniRef50_A6YH84 Cluster: Cystathionine gamma-synthase; n=2; Lact... 161 1e-38
UniRef50_Q96VU8 Cluster: Cystathionine beta-lyase; n=3; Pezizomy... 161 1e-38
UniRef50_A5GJ98 Cluster: MetC/metB Cystathionine beta-lyase/cyst... 161 2e-38
UniRef50_Q5UZS6 Cluster: Cystathionine gamma-synthase; n=3; cell... 161 2e-38
UniRef50_Q8TMW7 Cluster: Methionine gamma-lyase; n=3; Methanosar... 161 2e-38
UniRef50_A0NJV2 Cluster: O-succinylhomoserine thiol-lyase; n=2; ... 160 4e-38
UniRef50_Q9K024 Cluster: Cystathionine gamma-synthase; n=4; Neis... 159 6e-38
UniRef50_Q67R76 Cluster: Cystathionine gamma-lyase; n=13; Bacter... 159 6e-38
UniRef50_Q9KEQ0 Cluster: Methionine gamma lyase; n=13; Bacillace... 159 1e-37
UniRef50_Q0LLX7 Cluster: Cystathionine gamma-synthase; n=3; Bact... 158 1e-37
UniRef50_Q9KCE4 Cluster: Cystathionine gamma-synthase (O-succiny... 158 2e-37
UniRef50_Q2AGF7 Cluster: O-acetylhomoserine/O-acetylserine sulfh... 158 2e-37
UniRef50_P13254 Cluster: Methionine gamma-lyase; n=33; cellular ... 157 4e-37
UniRef50_Q8G436 Cluster: Possible cystathionine gamma lyase; n=3... 156 5e-37
UniRef50_Q1J8Q9 Cluster: Cystathionine beta-lyase; n=14; Bacilli... 156 5e-37
UniRef50_Q89V23 Cluster: O-acetylhomoserine sulfhydrylase; n=13;... 155 1e-36
UniRef50_Q49UL3 Cluster: Cystathionine beta-lyase cystathionine ... 155 1e-36
UniRef50_A1HQW4 Cluster: Cystathionine gamma-synthase; n=1; Ther... 153 5e-36
UniRef50_P00935 Cluster: Cystathionine gamma-synthase (EC 2.5.1.... 153 5e-36
UniRef50_P44502 Cluster: Cystathionine gamma-synthase (EC 2.5.1.... 152 1e-35
UniRef50_Q1IQ68 Cluster: Cystathionine gamma-synthase; n=1; Acid... 151 2e-35
UniRef50_Q97PS4 Cluster: Transulfuration enzyme family protein; ... 149 8e-35
UniRef50_Q0ALD7 Cluster: Cystathionine gamma-synthase; n=2; Hyph... 148 2e-34
UniRef50_Q8G805 Cluster: Cystathionine beta-lyase; n=2; Bifidoba... 147 2e-34
UniRef50_A4EYE9 Cluster: Cystathionine beta-lyase/cystathionine ... 147 2e-34
UniRef50_Q5QU17 Cluster: Methionine gamma-lyase; n=29; cellular ... 147 3e-34
UniRef50_Q65SV6 Cluster: Putative uncharacterized protein; n=1; ... 146 6e-34
UniRef50_A1ID11 Cluster: Cystathionine gamma-synthase; n=1; Cand... 146 6e-34
UniRef50_A1ZDN6 Cluster: Cystathionine beta-lyase; n=1; Microsci... 146 7e-34
UniRef50_A3VS82 Cluster: Cystathionine gamma-synthase; n=1; Parv... 145 1e-33
UniRef50_Q181I0 Cluster: Methionine gamma-lyase; n=2; Clostridiu... 145 1e-33
UniRef50_O94350 Cluster: Cystathionine beta-lyase; n=27; cellula... 145 1e-33
UniRef50_Q8RI67 Cluster: Cystathionine beta-lyase; n=2; Bacteria... 144 2e-33
UniRef50_Q4QFT8 Cluster: Cystathionine beta-lyase-like protein; ... 143 5e-33
UniRef50_Q5WAZ1 Cluster: Methionine gamma-lyase; n=1; Bacillus c... 142 1e-32
UniRef50_Q8R9M2 Cluster: Cystathionine beta-lyases/cystathionine... 140 3e-32
UniRef50_A0JSU6 Cluster: Cys/Met metabolism pyridoxal-phosphate-... 140 3e-32
UniRef50_O15564 Cluster: Methionine gamma-lyase; n=2; Trichomona... 140 3e-32
UniRef50_Q9KFD9 Cluster: Cystathionine gamma-synthase; n=3; Baci... 140 4e-32
UniRef50_A5WG79 Cluster: O-succinylhomoserine sulfhydrylase; n=6... 140 4e-32
UniRef50_A0JSB0 Cluster: O-acetylhomoserine/O-acetylserine sulfh... 140 5e-32
UniRef50_A3U7R8 Cluster: O-acetylhomoserine sulfhydrylase; n=8; ... 139 6e-32
UniRef50_Q3JCU1 Cluster: Cystathionine gamma-synthase; n=1; Nitr... 139 9e-32
UniRef50_A7DB98 Cluster: Cystathionine gamma-synthase; n=2; Meth... 139 9e-32
UniRef50_A1A0Q5 Cluster: Cystathionine beta-lyase; n=2; Bifidoba... 139 9e-32
UniRef50_Q4PK57 Cluster: Predicted cystathionine beta-lyase; n=1... 137 3e-31
UniRef50_A5KK19 Cluster: Putative uncharacterized protein; n=1; ... 137 3e-31
UniRef50_A5G8H3 Cluster: O-acetylhomoserine aminocarboxypropyltr... 137 3e-31
UniRef50_Q7X137 Cluster: Cystathionine gamma lyase-like protein;... 137 3e-31
UniRef50_Q89XR2 Cluster: O-acetylhomoserine sulfhydrylase; n=24;... 136 5e-31
UniRef50_A6LZ85 Cluster: O-acetylhomoserine aminocarboxypropyltr... 136 5e-31
UniRef50_A4FF27 Cluster: Methionine gamma-lyase; n=1; Saccharopo... 136 5e-31
UniRef50_Q5QWY7 Cluster: Cystathionine gamma-synthase; n=5; Prot... 136 8e-31
UniRef50_Q1VZU8 Cluster: Cystathionine beta-lyase; n=12; Bactero... 135 1e-30
UniRef50_Q4AEY8 Cluster: Cystathionine gamma-synthase; n=1; Chlo... 134 2e-30
UniRef50_Q67QQ8 Cluster: Cystathionine gamma-lyase; n=1; Symbiob... 133 4e-30
UniRef50_Q28Q09 Cluster: Cystathionine gamma-synthase; n=7; Rhod... 133 4e-30
UniRef50_Q5NPR0 Cluster: Cystathionine beta-lyases; n=5; Sphingo... 132 7e-30
UniRef50_Q1ELY9 Cluster: Cystathionine beta-lyases/cystathionine... 132 7e-30
UniRef50_A6W1L9 Cluster: Cystathionine gamma-synthase; n=10; Bac... 132 7e-30
UniRef50_A6NZI8 Cluster: Putative uncharacterized protein; n=1; ... 132 1e-29
UniRef50_Q1AT24 Cluster: Cystathionine gamma-synthase; n=2; Bact... 132 1e-29
UniRef50_A1ZIW0 Cluster: Cys/Met metabolism pyridoxal-phosphate-... 132 1e-29
UniRef50_Q7WKX4 Cluster: Cys/Met metabolism PLP-dependent enzyme... 130 3e-29
UniRef50_P55217 Cluster: Cystathionine gamma-synthase, chloropla... 130 3e-29
UniRef50_A5MZA3 Cluster: O-acetyl-L-homoserine sulfhydrylase-rel... 130 4e-29
UniRef50_Q8EM13 Cluster: O-acetylhomoserine sulfhydrylase; n=86;... 130 5e-29
UniRef50_Q86D27 Cluster: Methionine gamma-lyase 2; n=3; Entamoeb... 129 7e-29
UniRef50_P06106 Cluster: Protein MET17 [Includes: O-acetylhomose... 129 7e-29
UniRef50_A5WGJ5 Cluster: O-acetylhomoserine/O-acetylserine sulfh... 129 9e-29
UniRef50_Q97CC7 Cluster: Cystathionine beta lyase / O-succinylho... 128 1e-28
UniRef50_Q8RI68 Cluster: Cystathionine gamma-synthase; n=1; Fuso... 128 2e-28
UniRef50_Q1IZN0 Cluster: Cystathionine gamma-synthase; n=1; Dein... 128 2e-28
UniRef50_A7INF9 Cluster: O-acetylhomoserine aminocarboxypropyltr... 128 2e-28
UniRef50_UPI0000E46EAD Cluster: PREDICTED: similar to methionine... 128 2e-28
UniRef50_Q67KY0 Cluster: O-acetylhomoserine sulfhydrylase; n=28;... 127 4e-28
UniRef50_P55218 Cluster: O-succinylhomoserine sulfhydrylase; n=9... 127 4e-28
UniRef50_Q338K0 Cluster: Cys/Met metabolism PLP-dependent enzyme... 126 6e-28
UniRef50_Q0B7N7 Cluster: Cystathionine gamma-synthase; n=4; Beta... 125 1e-27
UniRef50_A4AND2 Cluster: Cystathionine gamma-lyase; n=2; cellula... 125 1e-27
UniRef50_A2Z703 Cluster: Putative uncharacterized protein; n=3; ... 125 1e-27
UniRef50_A2BL10 Cluster: Methionine gamma-lyase; n=1; Hypertherm... 125 1e-27
UniRef50_Q0SFV6 Cluster: O-acetylhomoserine aminocarboxypropyltr... 124 3e-27
UniRef50_A4AA77 Cluster: Cystathionine beta-lyase; n=2; Bacteria... 124 3e-27
UniRef50_Q399B4 Cluster: Cystathionine beta-lyase; n=15; Proteob... 124 3e-27
UniRef50_A5MZ94 Cluster: O-acetyl-L-homoserine sulfhydrylase-rel... 123 5e-27
UniRef50_Q6AJ03 Cluster: Probable cystathionine beta-lyase; n=1;... 123 6e-27
UniRef50_Q6W1U5 Cluster: Cystathionine gamma-synthase; n=2; Prot... 123 6e-27
UniRef50_Q31RB7 Cluster: O-acetylhomoserine/O-acetylserine sulfh... 122 8e-27
UniRef50_Q2S2T9 Cluster: Cystathionine beta-lyase MetC; n=1; Sal... 122 8e-27
UniRef50_Q11FS5 Cluster: Cystathionine beta-lyase; n=5; Alphapro... 122 8e-27
UniRef50_A4CKV8 Cluster: Cystathionine beta-lyase; n=11; Bactero... 122 8e-27
UniRef50_Q5K6Y9 Cluster: Cystathionine gamma-lyase, putative; n=... 122 8e-27
UniRef50_Q97MT9 Cluster: O-acetylhomoserine sulfhydrylase; n=4; ... 122 1e-26
UniRef50_A0L907 Cluster: Cystathionine gamma-synthase; n=1; Magn... 122 1e-26
UniRef50_Q5UZ20 Cluster: O-acetylhomoserine (Thiol)-lyase; n=10;... 122 1e-26
UniRef50_Q7VIG9 Cluster: O-acetylhomoserine (Thiol)-lyase MetY; ... 121 2e-26
UniRef50_Q1ITX7 Cluster: Cystathionine gamma-lyase; n=1; Acidoba... 121 2e-26
UniRef50_A3UCA9 Cluster: Cystathionine gamma-synthase; n=2; Hyph... 120 3e-26
UniRef50_A3JID5 Cluster: Cystathionine beta-lyase; n=3; Marinoba... 120 3e-26
UniRef50_UPI0000E47CE2 Cluster: PREDICTED: similar to cystathion... 120 4e-26
UniRef50_Q9RSD8 Cluster: O-acetylhomoserine (Thiol)-lyase/O-acet... 120 4e-26
UniRef50_A6UGP2 Cluster: Cystathionine gamma-synthase; n=1; Sino... 120 6e-26
UniRef50_A6GHC8 Cluster: Cystathionine gamma-synthase; n=1; Ples... 120 6e-26
UniRef50_A0V4A3 Cluster: O-acetylhomoserine/O-acetylserine sulfh... 119 7e-26
UniRef50_Q9V088 Cluster: MetB cystathionine gamma-synthase (EC 4... 119 7e-26
UniRef50_Q89VE2 Cluster: O-succinylhomoserine sulfhydrylase; n=7... 119 1e-25
UniRef50_Q895W3 Cluster: O-acetylhomoserine sulfhydrylase; n=40;... 119 1e-25
UniRef50_A0LY60 Cluster: O-succinylhomoserine sulfhydrylase; n=1... 117 3e-25
UniRef50_A5V1Q1 Cluster: Cystathionine gamma-synthase; n=2; Rose... 116 5e-25
UniRef50_Q46V95 Cluster: Cystathionine beta-lyase, bacterial; n=... 116 7e-25
UniRef50_Q1GNK9 Cluster: Cystathionine beta-lyase; n=4; Sphingom... 116 7e-25
UniRef50_A5CVL3 Cluster: O-succinylhomoserine sulfhydrylase; n=3... 116 7e-25
UniRef50_Q8NM00 Cluster: Cystathionine beta-lyases/cystathionine... 116 9e-25
UniRef50_A5ZYG7 Cluster: Putative uncharacterized protein; n=1; ... 116 9e-25
UniRef50_A1SMU4 Cluster: O-acetylhomoserine/O-acetylserine sulfh... 116 9e-25
UniRef50_Q1GQF1 Cluster: Cystathionine beta-lyase; n=1; Sphingop... 115 1e-24
UniRef50_Q5PBE9 Cluster: Cystathionine beta-lyase; n=1; Anaplasm... 115 2e-24
UniRef50_Q11C77 Cluster: Cystathionine beta-lyase; n=1; Mesorhiz... 115 2e-24
UniRef50_A5CMC2 Cluster: O-acetylhomoserine (Thiol)-lyase; n=2; ... 115 2e-24
UniRef50_Q8FRS9 Cluster: O-acetylhomoserine sulfhydrylase; n=8; ... 114 3e-24
UniRef50_Q47S97 Cluster: Cystathionine gamma-synthase; n=1; Ther... 114 3e-24
UniRef50_Q1IQ69 Cluster: Cystathionine beta-lyase; n=6; Bacteria... 114 3e-24
UniRef50_A1SSS1 Cluster: Cystathionine beta-lyase; n=10; Gammapr... 113 6e-24
UniRef50_Q97W69 Cluster: O-succinylhomoserine (Thiol)-lyase; n=5... 112 9e-24
UniRef50_Q5LWC9 Cluster: Cys/Met metabolism PLP-dependent enzyme... 112 1e-23
UniRef50_Q2JBH0 Cluster: O-succinylhomoserine sulfhydrylase; n=1... 112 1e-23
UniRef50_O02215 Cluster: Putative uncharacterized protein; n=3; ... 112 1e-23
UniRef50_Q07703 Cluster: Cystathionine beta-lyase; n=6; Burkhold... 112 1e-23
UniRef50_Q82YZ5 Cluster: Cystathionine gamma-synthase, putative;... 111 2e-23
UniRef50_A7DHV1 Cluster: O-acetylhomoserine aminocarboxypropyltr... 111 2e-23
UniRef50_P53101 Cluster: Cystathionine beta-lyase; n=5; Saccharo... 111 3e-23
UniRef50_Q7M844 Cluster: O-ACETYLHOMOSERINE (THIOL)-LYASE; n=1; ... 110 5e-23
UniRef50_Q2K0N3 Cluster: Cystathionine gamma-synthase protein; n... 110 5e-23
UniRef50_Q76K51 Cluster: O-acetyl-L-homoserine sulfhydrylase; n=... 110 5e-23
UniRef50_A1I7W3 Cluster: O-acetylhomoserine aminocarboxypropyltr... 110 5e-23
UniRef50_O69592 Cluster: O-succinylhomoserine sulfhydrylase; n=1... 109 6e-23
UniRef50_Q5GSE3 Cluster: Cystathionine beta-lyase; n=5; Wolbachi... 109 1e-22
UniRef50_A6PIC3 Cluster: Cystathionine beta-lyase; n=1; Shewanel... 108 1e-22
UniRef50_A5G088 Cluster: Cystathionine gamma-synthase; n=1; Acid... 108 1e-22
UniRef50_A0VE37 Cluster: Cystathionine beta-lyase; n=2; Comamona... 108 1e-22
UniRef50_A5EU95 Cluster: Cystathionine beta-lyase; n=1; Bradyrhi... 108 2e-22
UniRef50_Q98K64 Cluster: Methionine gamma-lyase; n=13; Bacteria|... 107 3e-22
UniRef50_Q52811 Cluster: Putative cystathionine beta-lyase; n=35... 106 6e-22
UniRef50_Q7UQA0 Cluster: Cystathionine gamma-synthase; n=4; Bact... 106 7e-22
UniRef50_A3X9V5 Cluster: Cystathionine gamma-synthase; n=12; Rho... 106 7e-22
UniRef50_A7HB44 Cluster: Cys/Met metabolism pyridoxal-phosphate-... 105 1e-21
UniRef50_A6GRN0 Cluster: Cystathionine beta-lyase; n=1; Limnobac... 105 1e-21
UniRef50_UPI00015BB00D Cluster: cystathionine gamma-synthase; n=... 105 2e-21
UniRef50_Q9SGU9 Cluster: F1N19.23; n=7; Magnoliophyta|Rep: F1N19... 105 2e-21
UniRef50_Q98LV9 Cluster: Methionine gamma lyase; n=4; Rhizobiale... 104 3e-21
UniRef50_P43623 Cluster: Putative cystathionine beta-lyase; n=11... 104 3e-21
UniRef50_Q8J0B2 Cluster: Homocysteine synthase-like protein; n=2... 103 4e-21
UniRef50_Q7M9C8 Cluster: O-ACETYLHOMOSERINE SULFHYDRYLASE; n=1; ... 103 5e-21
UniRef50_A0H5P3 Cluster: Cys/Met metabolism pyridoxal-phosphate-... 103 5e-21
UniRef50_UPI0000E0F9F5 Cluster: hypothetical protein OM2255_2257... 103 7e-21
UniRef50_Q62JZ5 Cluster: Cystathionine beta-lyase; n=37; Burkhol... 102 9e-21
UniRef50_Q493X0 Cluster: Beta-cystathionase; n=2; Enterobacteria... 102 9e-21
UniRef50_Q0APK0 Cluster: Cystathionine beta-lyase; n=1; Maricaul... 102 9e-21
UniRef50_A0JYV8 Cluster: Cystathionine gamma-synthase; n=8; Acti... 102 1e-20
UniRef50_Q5FUW3 Cluster: Cystathionine beta-lyase; n=3; Acetobac... 101 2e-20
UniRef50_Q01X62 Cluster: Cystathionine gamma-synthase; n=1; Soli... 101 2e-20
UniRef50_A6QZA3 Cluster: Cystathionine gamma-lyase; n=1; Ajellom... 101 2e-20
UniRef50_Q7WM51 Cluster: Cystathionase beta-lyase; n=3; Proteoba... 101 2e-20
UniRef50_Q9X0Z7 Cluster: Cystathionine gamma-synthase; n=2; Ther... 101 3e-20
UniRef50_Q45278 Cluster: Aminotransferase and dihydrorhizobitoxi... 101 3e-20
UniRef50_Q98KA4 Cluster: Probable cystathionine/methionine gamma... 100 4e-20
UniRef50_A7S3X8 Cluster: Predicted protein; n=1; Nematostella ve... 100 4e-20
UniRef50_Q1V2M7 Cluster: Cystathionine beta-lyase; n=2; Candidat... 100 5e-20
UniRef50_A6Q4H8 Cluster: O-acetylhomoserine sulfhydrylase; n=3; ... 100 5e-20
UniRef50_A3SR24 Cluster: Cystathionine gamma-synthase; n=3; Alph... 100 5e-20
UniRef50_Q3IV09 Cluster: O-acetylhomoserine sulfhydrylase; n=1; ... 99 6e-20
UniRef50_Q67VG6 Cluster: Putative O-succinylhomoserine (Thiol)-l... 100 9e-20
UniRef50_Q6L1U0 Cluster: Cystathionine beta-lyase; n=1; Picrophi... 100 9e-20
UniRef50_A7H1V2 Cluster: Cystathionine beta-lyase; n=15; Campylo... 99 1e-19
UniRef50_Q7W586 Cluster: Cystathionine beta-lyase; n=3; Bordetel... 99 1e-19
UniRef50_Q979X4 Cluster: Cystathionine beta lyase / O-succinylho... 99 1e-19
UniRef50_A6W2A4 Cluster: Cystathionine beta-lyase; n=1; Marinomo... 98 2e-19
UniRef50_Q59829 Cluster: Putative cystathionine gamma-lyase; n=8... 97 3e-19
UniRef50_Q26GX1 Cluster: Cys/Met metabolism PLP-dependent enzyme... 97 6e-19
UniRef50_Q1GVW8 Cluster: Cystathionine gamma-lyase; n=15; Bacter... 97 6e-19
UniRef50_Q11MH2 Cluster: Cys/Met metabolism pyridoxal-phosphate-... 97 6e-19
UniRef50_A3K0Q5 Cluster: O-succinylhomoserine sulfhydrylase; n=3... 97 6e-19
UniRef50_A2Y9X5 Cluster: Putative uncharacterized protein; n=1; ... 97 6e-19
UniRef50_A4S3Y0 Cluster: Putative 2nd cystathione gamma synthase... 96 8e-19
UniRef50_Q4Q511 Cluster: Cystathionine beta-lyase, putative; n=3... 96 8e-19
UniRef50_A3PXR9 Cluster: Cys/Met metabolism pyridoxal-phosphate-... 95 2e-18
UniRef50_Q3A8R5 Cluster: O-acetylhomoserine/O-acetylserine sulfh... 95 2e-18
UniRef50_A6GJL1 Cluster: Methionine gamma-lyase; n=1; Plesiocyst... 94 4e-18
UniRef50_Q0C2A8 Cluster: Cystathionine beta-lyase; n=1; Hyphomon... 93 1e-17
UniRef50_P44527 Cluster: Cystathionine beta-lyase; n=78; Gammapr... 93 1e-17
UniRef50_Q5LN68 Cluster: Cys/Met metabolism PLP-dependent enzyme... 92 1e-17
UniRef50_Q6N7A9 Cluster: Putative homocysteine synthase; n=1; Rh... 92 2e-17
UniRef50_Q13Z52 Cluster: Cystathionine beta-lyase; n=2; Burkhold... 92 2e-17
UniRef50_A3VUE2 Cluster: Cystathionine beta-lyase; n=1; Parvular... 91 2e-17
UniRef50_Q1DAY0 Cluster: Cys/Met metabolism PLP-dependent enzyme... 91 3e-17
UniRef50_Q6MN74 Cluster: Cys/Met metabolism lyase; n=1; Bdellovi... 90 7e-17
UniRef50_Q7X1G1 Cluster: Lfe147p1; n=2; Leptospirillum|Rep: Lfe1... 87 6e-16
UniRef50_Q1NS60 Cluster: O-acetylhomoserine aminocarboxypropyltr... 87 6e-16
UniRef50_Q62BJ4 Cluster: Trans-sulfuration enzyme family protein... 86 8e-16
UniRef50_Q0B5H9 Cluster: Cys/Met metabolism pyridoxal-phosphate-... 86 1e-15
UniRef50_A7CL93 Cluster: Cys/Met metabolism pyridoxal-phosphate-... 85 3e-15
UniRef50_A1CUZ3 Cluster: Homocysteine synthase, putative; n=1; N... 84 3e-15
UniRef50_A1W861 Cluster: Cys/Met metabolism pyridoxal-phosphate-... 84 5e-15
UniRef50_Q5NQQ3 Cluster: Cystathionine beta-lyase; n=41; Proteob... 83 1e-14
UniRef50_Q7P3Q8 Cluster: Methionine gamma-lyase; n=1; Fusobacter... 82 1e-14
UniRef50_Q6F7Q9 Cluster: Putative cystathionine beta-lyase, PLP-... 80 7e-14
UniRef50_Q9YA71 Cluster: Cystathionine gamma-synthase; n=1; Aero... 80 7e-14
UniRef50_O42851 Cluster: Uncharacterized trans-sulfuration enzym... 80 7e-14
UniRef50_A7TA32 Cluster: Predicted protein; n=1; Nematostella ve... 79 1e-13
UniRef50_P38716 Cluster: Uncharacterized trans-sulfuration enzym... 79 2e-13
UniRef50_A5W0L6 Cluster: Cys/Met metabolism pyridoxal-phosphate-... 78 2e-13
UniRef50_Q64XN5 Cluster: O-acetylhomoserine sulfhydrylase; n=3; ... 78 3e-13
UniRef50_A3UCF8 Cluster: Cystathionine beta-lyase; n=1; Oceanica... 78 3e-13
UniRef50_Q28LE3 Cluster: Cys/Met metabolism pyridoxal-phosphate-... 77 5e-13
UniRef50_A1TP30 Cluster: Cys/Met metabolism pyridoxal-phosphate-... 73 1e-11
UniRef50_Q00ZR7 Cluster: Cystathionine gamma-synthase; n=1; Ostr... 73 1e-11
UniRef50_Q4WFS7 Cluster: Cystathionine beta-lyase; n=2; Pezizomy... 73 1e-11
UniRef50_A1DJG8 Cluster: Cystathionine gamma-synthase; n=1; Neos... 69 1e-10
UniRef50_Q756K4 Cluster: AER250Cp; n=6; Saccharomycetales|Rep: A... 69 2e-10
UniRef50_A1D936 Cluster: Cystathionine gamma-synthase; n=21; Asc... 68 3e-10
UniRef50_Q0V7G5 Cluster: Putative uncharacterized protein; n=1; ... 65 2e-09
UniRef50_A5BR77 Cluster: Putative uncharacterized protein; n=1; ... 64 4e-09
UniRef50_Q2UI88 Cluster: Cystathionine beta-lyases/cystathionine... 64 4e-09
UniRef50_Q1QM61 Cluster: Cys/Met metabolism pyridoxal-phosphate-... 60 6e-08
UniRef50_UPI0000E4882F Cluster: PREDICTED: hypothetical protein,... 59 1e-07
UniRef50_A7CR38 Cluster: Cys/Met metabolism pyridoxal-phosphate-... 59 1e-07
UniRef50_A4AZ61 Cluster: Homocysteine synthase; n=7; Gammaproteo... 57 4e-07
UniRef50_UPI000155C3C4 Cluster: PREDICTED: similar to cystathion... 56 8e-07
UniRef50_Q83WD5 Cluster: Putative cystathionine/methionine gamma... 56 1e-06
UniRef50_Q12198 Cluster: Putative cystathionine gamma-synthase Y... 55 2e-06
UniRef50_A2BPN5 Cluster: Possible Cystathionine gamma-synthase; ... 54 3e-06
UniRef50_Q3AI46 Cluster: Possible cystathionine gamma-synthase; ... 54 4e-06
UniRef50_Q6FK75 Cluster: Similar to sp|P47164 Saccharomyces cere... 53 7e-06
UniRef50_P47164 Cluster: Cystathionine gamma-synthase (EC 2.5.1.... 53 1e-05
UniRef50_A7TG47 Cluster: Putative uncharacterized protein; n=1; ... 52 2e-05
UniRef50_Q54RW8 Cluster: Putative uncharacterized protein; n=1; ... 52 2e-05
UniRef50_Q67LU9 Cluster: Cystathionine beta-lyase; n=2; Bacteria... 51 3e-05
UniRef50_Q2HHZ6 Cluster: Putative uncharacterized protein; n=1; ... 51 4e-05
UniRef50_Q6CWG2 Cluster: Similar to sp|P47164 Saccharomyces cere... 49 1e-04
UniRef50_Q6C8S4 Cluster: Similar to tr|Q86ZL4 Podospora anserina... 49 2e-04
UniRef50_Q2U598 Cluster: Cystathionine beta-lyases/cystathionine... 48 2e-04
UniRef50_Q2H8C4 Cluster: Putative uncharacterized protein; n=1; ... 48 2e-04
UniRef50_Q8F9S7 Cluster: Cystathionine gamma-synthase; n=4; Lept... 48 3e-04
UniRef50_A6R1N2 Cluster: Cystathionine gamma-synthase; n=1; Ajel... 48 3e-04
UniRef50_A3JA39 Cluster: O-acetylhomoserine/O-acetylserine sulfh... 48 4e-04
UniRef50_A4QZ48 Cluster: Putative uncharacterized protein; n=1; ... 48 4e-04
UniRef50_O74314 Cluster: Probable cystathionine gamma-synthase (... 48 4e-04
UniRef50_Q7SD09 Cluster: Putative uncharacterized protein NCU081... 47 5e-04
UniRef50_A3LX62 Cluster: Predicted protein; n=6; Saccharomycetal... 46 8e-04
UniRef50_Q8G801 Cluster: Putative uncharacterized protein; n=2; ... 46 0.001
UniRef50_Q5KL05 Cluster: Cystathionine gamma-synthase, putative;... 45 0.002
UniRef50_Q2UJR0 Cluster: Cystathionine beta-lyases/cystathionine... 44 0.003
UniRef50_P38675 Cluster: Cystathionine gamma-synthase (EC 2.5.1.... 44 0.004
UniRef50_A4XL24 Cluster: Aminotransferase, class I and II; n=1; ... 43 0.010
UniRef50_UPI000023F0A1 Cluster: hypothetical protein FG08909.1; ... 42 0.014
UniRef50_A4R0S4 Cluster: Putative uncharacterized protein; n=1; ... 42 0.014
UniRef50_Q2HFC3 Cluster: Putative uncharacterized protein; n=1; ... 42 0.024
UniRef50_O58821 Cluster: Putative uncharacterized protein PH1094... 41 0.042
UniRef50_Q1VY21 Cluster: Coproporphyrinogen III oxidase; n=1; Ps... 40 0.055
UniRef50_A7MW66 Cluster: Putative uncharacterized protein; n=3; ... 40 0.055
UniRef50_Q58097 Cluster: Probable aspartate aminotransferase 2; ... 40 0.055
UniRef50_UPI000023F307 Cluster: hypothetical protein FG00503.1; ... 39 0.13
UniRef50_O14209 Cluster: Uncharacterized aminotransferase C6B12.... 39 0.13
UniRef50_Q98EJ5 Cluster: Aspartate aminotransferase; n=3; cellul... 39 0.17
UniRef50_Q8A2D0 Cluster: Aspartate aminotransferase; n=1; Bacter... 39 0.17
UniRef50_Q4P760 Cluster: Putative uncharacterized protein; n=1; ... 39 0.17
UniRef50_A6C1Z0 Cluster: Selenocysteine lyase; n=1; Planctomyces... 38 0.22
UniRef50_A5HZP1 Cluster: Glycine cleavage system P protein; n=4;... 38 0.22
UniRef50_Q8RA65 Cluster: Cystathionine beta-lyases/cystathionine... 38 0.29
UniRef50_Q5X017 Cluster: Putative uncharacterized protein; n=1; ... 38 0.29
UniRef50_Q1IU09 Cluster: Putative uncharacterized protein; n=1; ... 38 0.29
UniRef50_Q1E2P4 Cluster: Putative uncharacterized protein; n=1; ... 38 0.29
UniRef50_Q8R5Q4 Cluster: Histidinol-phosphate aminotransferase; ... 38 0.29
UniRef50_Q58365 Cluster: Histidinol-phosphate aminotransferase; ... 38 0.29
UniRef50_Q60317 Cluster: Probable aspartate aminotransferase 1; ... 38 0.29
UniRef50_Q2AE33 Cluster: Glycine cleavage system P-protein; n=1;... 38 0.39
UniRef50_Q8Y5X8 Cluster: Histidinol-phosphate aminotransferase; ... 38 0.39
UniRef50_Q9Y9P0 Cluster: Aspartate aminotransferase; n=3; Thermo... 37 0.68
UniRef50_Q8R6L3 Cluster: Selenocysteine lyase; n=7; Clostridia|R... 36 0.90
UniRef50_A4IWT8 Cluster: Aminotransferase, class I/II; n=12; Fra... 36 0.90
UniRef50_Q3T4B9 Cluster: NADH-ubiquinone oxidoreductase chain 4;... 36 0.90
UniRef50_A7TP63 Cluster: Putative uncharacterized protein; n=1; ... 36 0.90
UniRef50_A7DS52 Cluster: Aminotransferase, class I and II; n=1; ... 36 0.90
UniRef50_Q9K5N2 Cluster: Aminotransferase required for NAD biosy... 36 1.2
UniRef50_Q98AR6 Cluster: Aspartate transaminase; n=2; Mesorhizob... 36 1.2
UniRef50_Q88UE6 Cluster: Histidinol-phosphate aminotransferase; ... 36 1.2
UniRef50_Q8NMH4 Cluster: PLP-dependent aminotransferases; n=5; C... 36 1.6
UniRef50_Q2BCQ0 Cluster: Putative uncharacterized protein; n=1; ... 36 1.6
UniRef50_A6TKT2 Cluster: Histidinol-phosphate aminotransferase; ... 36 1.6
UniRef50_Q6BZ38 Cluster: Debaryomyces hansenii chromosome A of s... 36 1.6
UniRef50_Q2NEQ0 Cluster: HisC; n=2; Methanobacteriaceae|Rep: His... 36 1.6
UniRef50_UPI00015B5B66 Cluster: PREDICTED: similar to kynurenine... 35 2.1
UniRef50_Q5FUM7 Cluster: Prolyl-oligopeptidase; n=1; Gluconobact... 35 2.1
UniRef50_A7NVA1 Cluster: Chromosome chr18 scaffold_1, whole geno... 35 2.1
UniRef50_O51111 Cluster: Probable cysteine desulfurase; n=3; Bor... 35 2.1
UniRef50_Q8YGW6 Cluster: CYSTEINE DESULFHYDRASE / SELENOCYSTEINE... 35 2.7
UniRef50_Q186L1 Cluster: Aminomethyltransferase; n=20; Firmicute... 35 2.7
UniRef50_A6LSW9 Cluster: Putative L-threonine-O-3-phosphate deca... 35 2.7
UniRef50_Q7RBN5 Cluster: Arabidopsis thaliana T27G7.17, putative... 35 2.7
UniRef50_A5UT24 Cluster: Aminotransferase, class V; n=4; Chlorof... 34 3.6
UniRef50_Q8H0S1 Cluster: At1g28060/F13K9_16; n=6; Magnoliophyta|... 34 3.6
UniRef50_Q5CUF9 Cluster: Conserved COOH terminal-specific cystei... 34 3.6
UniRef50_A7D358 Cluster: Aminotransferase, class I and II; n=1; ... 34 3.6
UniRef50_Q0RYX5 Cluster: Glycine dehydrogenase (Decarboxylating)... 34 4.8
UniRef50_Q8YQG4 Cluster: Alr3867 protein; n=3; Bacteria|Rep: Alr... 33 6.3
UniRef50_Q7NDX4 Cluster: Glr4108 protein; n=17; cellular organis... 33 6.3
UniRef50_Q46955 Cluster: O antigen polymerase; n=1; Escherichia ... 33 6.3
UniRef50_A4B3S6 Cluster: Probable aspartate aminotransferase; n=... 33 6.3
UniRef50_A3DJF2 Cluster: Histidinol-phosphate aminotransferase; ... 33 6.3
UniRef50_A4RC33 Cluster: Putative uncharacterized protein; n=2; ... 33 6.3
UniRef50_UPI00015B9512 Cluster: UPI00015B9512 related cluster; n... 33 8.4
UniRef50_A7GCC1 Cluster: Dipeptidase; n=11; Bacteria|Rep: Dipept... 33 8.4
UniRef50_Q5Z958 Cluster: Putative uncharacterized protein P0659D... 33 8.4
UniRef50_A7UG05 Cluster: Orf2 protein; n=1; Phaeosphaeria nodoru... 33 8.4
UniRef50_Q6ABU3 Cluster: Putative phenylalanine aminotransferase... 33 8.4
>UniRef50_Q17DR1 Cluster: Cystathionine beta-lyase; n=6;
Coelomata|Rep: Cystathionine beta-lyase - Aedes aegypti
(Yellowfever mosquito)
Length = 438
Score = 308 bits (757), Expect = 8e-83
Identities = 144/237 (60%), Positives = 177/237 (74%)
Frame = +2
Query: 92 VENKIGMADHGFLKQKPGFATIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPAPAEHTGFE 271
+ N + A+ GF Q GFAT AIH GQ+ E+W S AVV PI STTFKQ PA+H G+E
Sbjct: 6 ITNGVERAEDGFRAQPKGFATKAIHVGQDAEQWKSRAVVPPISMSTTFKQFGPAQHAGYE 65
Query: 272 YGRSGNPTRNTLEECLAALDGGKYGLTFASXXXXXXXXXXXXNHGDHIVSSDDVYGGTNR 451
YGRSGNPTR+ LE CLA+LD GKYGLTF+S + GDHIV+ DD+YGGTNR
Sbjct: 66 YGRSGNPTRDVLERCLASLDNGKYGLTFSSGLGVTTTVITMLSAGDHIVAGDDLYGGTNR 125
Query: 452 LLRQVIARLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSR 631
LLR+V ++ I F D T++ KV+ A++ NTK+ WIETPTNPLLKV+DIEA+ ++A
Sbjct: 126 LLRKVAMKMNIEVDFVDCTDLAKVEAAVKPNTKLFWIETPTNPLLKVIDIEAVSEVAHKF 185
Query: 632 GDIIVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVNDKAIGXKL 802
++VVVDNTFL+ YLQRPL GADIVMYSLTKYMNGHSDVIMGAAI+ND+A+ +L
Sbjct: 186 PGVVVVVDNTFLSAYLQRPLDLGADIVMYSLTKYMNGHSDVIMGAAIMNDEALYEQL 242
>UniRef50_P32929 Cluster: Cystathionine gamma-lyase; n=38; cellular
organisms|Rep: Cystathionine gamma-lyase - Homo sapiens
(Human)
Length = 405
Score = 272 bits (668), Expect = 5e-72
Identities = 128/230 (55%), Positives = 155/230 (67%)
Frame = +2
Query: 113 ADHGFLKQKPGFATIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPAPAEHTGFEYGRSGNP 292
+ GFL FAT AIH GQ+PE+W S AVV PI STTFKQ AP +H+GFEY RSGNP
Sbjct: 7 SSQGFLPHFQHFATQAIHVGQDPEQWTSRAVVPPISLSTTFKQGAPGQHSGFEYSRSGNP 66
Query: 293 TRNTLEECLAALDGGKYGLTFASXXXXXXXXXXXXNHGDHIVSSDDVYGGTNRLLRQVIA 472
TRN LE+ +AALDG KY L FAS GD I+ DDVYGGTNR RQV +
Sbjct: 67 TRNCLEKAVAALDGAKYCLAFASGLAATVTITHLLKAGDQIICMDDVYGGTNRYFRQVAS 126
Query: 473 RLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVV 652
G+ +F D + I+ ++ A+ TK++WIETPTNP KV+DIE I GDII+VV
Sbjct: 127 EFGLKISFVDCSKIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIVHKHGDIILVV 186
Query: 653 DNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVNDKAIGXKL 802
DNTF++PY QRPL GADI MYS TKYMNGHSDV+MG VN +++ +L
Sbjct: 187 DNTFMSPYFQRPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRL 236
>UniRef50_Q8VCN5 Cluster: Cystathionine gamma-lyase; n=39;
Eukaryota|Rep: Cystathionine gamma-lyase - Mus musculus
(Mouse)
Length = 398
Score = 258 bits (633), Expect = 9e-68
Identities = 122/227 (53%), Positives = 150/227 (66%)
Frame = +2
Query: 122 GFLKQKPGFATIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPAPAEHTGFEYGRSGNPTRN 301
GFL FAT AIH GQEPE+WNS AVV PI +TTFKQ P + +GFEY RSGNPTRN
Sbjct: 9 GFLPSFQHFATQAIHVGQEPEQWNSRAVVLPISLATTFKQDFPGQSSGFEYSRSGNPTRN 68
Query: 302 TLEECLAALDGGKYGLTFASXXXXXXXXXXXXNHGDHIVSSDDVYGGTNRLLRQVIARLG 481
LE+ +AALDG K+ L FAS GD I+ D+VYGGTNR R+V + G
Sbjct: 69 CLEKAVAALDGAKHSLAFASGLAATITITHLLKAGDEIICMDEVYGGTNRYFRRVASEFG 128
Query: 482 INTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNT 661
+ +F D + + ++ A+ TK++WIETPTNP LK+ DI A +I RGDII+VVDNT
Sbjct: 129 LKISFVDCSKTKLLEAAITPQTKLVWIETPTNPTLKLADIGACAQIVHKRGDIILVVDNT 188
Query: 662 FLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVNDKAIGXKL 802
F++ Y QRPL GADI M S TKYMNGHSDV+MG VN + +L
Sbjct: 189 FMSAYFQRPLALGADICMCSATKYMNGHSDVVMGLVSVNSDDLNSRL 235
>UniRef50_Q23CV0 Cluster: Cystathionine beta-lyase; n=3;
Oligohymenophorea|Rep: Cystathionine beta-lyase -
Tetrahymena thermophila SB210
Length = 409
Score = 229 bits (560), Expect = 6e-59
Identities = 111/227 (48%), Positives = 150/227 (66%), Gaps = 3/227 (1%)
Frame = +2
Query: 131 KQKPGFATIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPAPAE-HTGFEYGRSGNPTRNTL 307
K+ GFAT AIHAGQ+P++ + + V PI STTF Q AP + ++ +EY R G PTR+
Sbjct: 18 KKNKGFATKAIHAGQDPDQVHGSVNV-PIHLSTTFAQKAPTDFYSQYEYARGGTPTRHAF 76
Query: 308 EECLAALDGGKYGLTFASXXXXXXXXXXXXNHGDHIVSSDDVYGGTNRLLRQ-VIARLGI 484
EEC+AA + G+Y + F+S HI+ SDDVYGGTNR +R+ + +
Sbjct: 77 EECIAACENGEYAIAFSSGCAAMTCVLHSLPKESHIIVSDDVYGGTNRYMRRFAVEKFNF 136
Query: 485 NTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIAR-SRGDIIVVVDNT 661
N F D T+ E KNA +ENT ++WIETPTNPL+K+VDIEA+V I R + D V+VDNT
Sbjct: 137 NVEFVDLTDTEAFKNAFKENTALVWIETPTNPLIKLVDIEALVNITREKKKDTWVLVDNT 196
Query: 662 FLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVNDKAIGXKL 802
F +PYLQ P+ G DI ++S++KY+ GHSDVIMGA + N K + KL
Sbjct: 197 FASPYLQNPMDLGVDITLHSVSKYIGGHSDVIMGALVFNGKEMKDKL 243
>UniRef50_Q129P6 Cluster: Cystathionine gamma-synthase; n=11;
cellular organisms|Rep: Cystathionine gamma-synthase -
Polaromonas sp. (strain JS666 / ATCC BAA-500)
Length = 381
Score = 225 bits (550), Expect = 1e-57
Identities = 106/219 (48%), Positives = 148/219 (67%)
Frame = +2
Query: 146 FATIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPAPAEHTGFEYGRSGNPTRNTLEECLAA 325
F+T AIHAGQ P + A++TP+ S+TF Q AP +H G++YGR+ NPTR+ LE +AA
Sbjct: 3 FSTQAIHAGQ-PADPTTGAIMTPVYLSSTFVQQAPGQHKGYDYGRTANPTRSALEANIAA 61
Query: 326 LDGGKYGLTFASXXXXXXXXXXXXNHGDHIVSSDDVYGGTNRLLRQVIARLGINTTFTDF 505
L+ G YGL FAS + GDH+V D+YGGT RL+ +V AR GI +F D
Sbjct: 62 LEDGTYGLAFASGLAAESTVLQSLSSGDHVVCGQDLYGGTYRLMTKVFARFGIEASFVDA 121
Query: 506 TNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQR 685
T+ ++ A++ T+++W+ETP+NPLL V DI AI ++A + VDNTF +PYLQ+
Sbjct: 122 TSPGAIRAALRPQTRLVWLETPSNPLLTVCDIAAIAQLAHEH-QARLAVDNTFASPYLQQ 180
Query: 686 PLXFGADIVMYSLTKYMNGHSDVIMGAAIVNDKAIGXKL 802
PL GADIV++S TKY+ GHSDVI GA ++ND+A+ +L
Sbjct: 181 PLRLGADIVIHSTTKYLGGHSDVIGGALVMNDEALYQEL 219
>UniRef50_P24601 Cluster: Probable cystathionine gamma-synthase (EC
2.5.1.48) (CGS) (O- succinylhomoserine (thiol)-lyase);
n=52; cellular organisms|Rep: Probable cystathionine
gamma-synthase (EC 2.5.1.48) (CGS) (O-
succinylhomoserine (thiol)-lyase) - Herpetosiphon
aurantiacus (Herpetosiphon giganteus)
Length = 319
Score = 223 bits (545), Expect = 4e-57
Identities = 105/220 (47%), Positives = 146/220 (66%)
Frame = +2
Query: 143 GFATIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPAPAEHTGFEYGRSGNPTRNTLEECLA 322
GFAT AIHAGQ+PE + AV+ PI ++T+ Q +HTG+EY R+ NPTR L+ CLA
Sbjct: 4 GFATRAIHAGQDPESV-TGAVIVPIYQTSTYAQRGVGDHTGYEYSRTDNPTRTALQTCLA 62
Query: 323 ALDGGKYGLTFASXXXXXXXXXXXXNHGDHIVSSDDVYGGTNRLLRQVIARLGINTTFTD 502
AL+ K+ L FAS GDH++ DDVYGGT RL ++V+ G++ F D
Sbjct: 63 ALEEAKHALVFASGLGASTTLMLMLKAGDHVICGDDVYGGTYRLFQRVMTEHGLSFDFID 122
Query: 503 FTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQ 682
+ E V+ A++ NT++IW+ETPTNPLLK+ I AI ++AR G I +VDNTF +PY Q
Sbjct: 123 MADPEAVRAAIKPNTRLIWLETPTNPLLKLAPIAAITRVAREHG-IWTIVDNTFASPYNQ 181
Query: 683 RPLXFGADIVMYSLTKYMNGHSDVIMGAAIVNDKAIGXKL 802
RP+ GAD+V++S TKY+ GHSDV+ GA + ++ + KL
Sbjct: 182 RPITLGADMVLHSTTKYIGGHSDVVGGAIMTSNDELYEKL 221
>UniRef50_UPI0000F2BB70 Cluster: PREDICTED: similar to Chain A,
Crystal Structure Of Human Cystathionine Gamma Lyase;
n=3; Mammalia|Rep: PREDICTED: similar to Chain A,
Crystal Structure Of Human Cystathionine Gamma Lyase -
Monodelphis domestica
Length = 500
Score = 215 bits (525), Expect = 1e-54
Identities = 102/194 (52%), Positives = 124/194 (63%)
Frame = +2
Query: 101 KIGMADHGFLKQKPGFATIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPAPAEHTGFEYGR 280
K G D GF P FAT AIHA QEPE+W+ VV PI STTFKQ AP H GFEY R
Sbjct: 3 KGGTPDGGFQPPFPHFATQAIHAAQEPEQWSGQPVVAPISLSTTFKQTAPGCHAGFEYSR 62
Query: 281 SGNPTRNTLEECLAALDGGKYGLTFASXXXXXXXXXXXXNHGDHIVSSDDVYGGTNRLLR 460
SGNPTRN LE+ +A LDG KY L FAS GDHIV +DVYGGTNR R
Sbjct: 63 SGNPTRNCLEKAVATLDGAKYCLAFASGLAATLNITHLLKAGDHIVCMNDVYGGTNRYFR 122
Query: 461 QVIARLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDI 640
+V LG+ +F D + +E + A+ TK++WIETPTNP LKV+DI+ ++ GD+
Sbjct: 123 RVATELGLKISFVDCSKLELLNAAITPETKLVWIETPTNPGLKVIDIKGCAQVVHKHGDV 182
Query: 641 IVVVDNTFLTPYLQ 682
I+VVDNTF++ Y Q
Sbjct: 183 ILVVDNTFMSAYFQ 196
>UniRef50_Q74EL7 Cluster: Cystathionine beta-lyase; n=5;
Bacteria|Rep: Cystathionine beta-lyase - Geobacter
sulfurreducens
Length = 378
Score = 205 bits (501), Expect = 9e-52
Identities = 98/220 (44%), Positives = 144/220 (65%), Gaps = 1/220 (0%)
Frame = +2
Query: 146 FATIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPAPAEHTG-FEYGRSGNPTRNTLEECLA 322
F T IH G+E + + A+ PI ++T++Q + +H G ++Y RS NPTR LEE +A
Sbjct: 3 FGTRIIHTGREIDP-TTGALSVPIYQTSTYRQES-VDHFGKYDYARSDNPTREALEETVA 60
Query: 323 ALDGGKYGLTFASXXXXXXXXXXXXNHGDHIVSSDDVYGGTNRLLRQVIARLGINTTFTD 502
L+ G G FAS + GDH+V +DVYGGT R L Q+ +RLG+ +TF D
Sbjct: 61 QLENGTRGFAFASGMAAISSTLLLFSPGDHLVVCEDVYGGTFRALTQLFSRLGVESTFVD 120
Query: 503 FTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQ 682
T+ ++ A + NTK +++ETP+NPL+K+ D+ A ++AR RG I +VDNTF+TPYLQ
Sbjct: 121 ATDTAAIEAAFRPNTKGLYLETPSNPLMKITDLAAAARLARERG-AITLVDNTFMTPYLQ 179
Query: 683 RPLXFGADIVMYSLTKYMNGHSDVIMGAAIVNDKAIGXKL 802
RPL G D+V++S TK++NGHSDV+ G A+V D +G ++
Sbjct: 180 RPLDLGCDVVLHSGTKFLNGHSDVVCGFAVVRDPELGQRI 219
>UniRef50_Q9EWF9 Cluster: Cystathionine gamma-synthase; n=6;
Bacteria|Rep: Cystathionine gamma-synthase -
Streptomyces coelicolor
Length = 386
Score = 203 bits (495), Expect = 5e-51
Identities = 105/221 (47%), Positives = 138/221 (62%), Gaps = 2/221 (0%)
Frame = +2
Query: 146 FATIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPAPAE-HTGFEYGRSGNPTRNTLEECLA 322
F T+AIHAG + + AVV PI +T+KQ G+EY RS NPTR LEE LA
Sbjct: 12 FETLAIHAGNTADPL-TGAVVPPIYQVSTYKQDGVGGLRGGYEYSRSANPTRTALEENLA 70
Query: 323 ALDGGKYGLTFASXXXXXX-XXXXXXNHGDHIVSSDDVYGGTNRLLRQVIARLGINTTFT 499
AL+GG+ GL FAS GDH+V +D YGGT RL +V R G+ +
Sbjct: 71 ALEGGRRGLAFASGLAAEDCLLRTLLRPGDHVVIPNDAYGGTFRLFAKVATRWGVEWSVA 130
Query: 500 DFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYL 679
D ++ V+ A+ TK +W+ETP+NPLL + DI + ++AR G +VV DNTF TPYL
Sbjct: 131 DTSDAAAVRAALTPKTKAVWVETPSNPLLGITDIAQVAQVARDAGARLVV-DNTFATPYL 189
Query: 680 QRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVNDKAIGXKL 802
Q+PL GAD+V++SLTKYM GHSDV+ GA IV D+ +G +L
Sbjct: 190 QQPLALGADVVVHSLTKYMGGHSDVVGGALIVGDQELGEEL 230
>UniRef50_P56069 Cluster: Cystathionine gamma-synthase (EC 2.5.1.48)
(CGS) (O-succinylhomoserine (thiol)-lyase); n=24;
Bacteria|Rep: Cystathionine gamma-synthase (EC 2.5.1.48)
(CGS) (O-succinylhomoserine (thiol)-lyase) -
Helicobacter pylori (Campylobacter pylori)
Length = 380
Score = 202 bits (494), Expect = 6e-51
Identities = 96/217 (44%), Positives = 135/217 (62%)
Frame = +2
Query: 152 TIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPAPAEHTGFEYGRSGNPTRNTLEECLAALD 331
T IH G E + AV PI ++T++Q A H G+EY RSGNPTR LEE +A L+
Sbjct: 5 TKLIHGGIS-EDATTGAVSVPIYQTSTYRQDAIGRHKGYEYSRSGNPTRFALEELIADLE 63
Query: 332 GGKYGLTFASXXXXXXXXXXXXNHGDHIVSSDDVYGGTNRLLRQVIARLGINTTFTDFTN 511
GG G FAS GDH++ DDVYGGT RL QV+ + G++ T D ++
Sbjct: 64 GGVKGFAFASGLAGIHAVFSLLQSGDHVLLGDDVYGGTFRLFNQVLVKNGLSCTIIDTSD 123
Query: 512 IEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQRPL 691
I ++K A++ NTK +++ETP+NPLLK+ D+ +A+ G ++ +VDNTF TPY Q PL
Sbjct: 124 ISQIKKAIKPNTKALYLETPSNPLLKITDLAQCASVAKDHG-LLTIVDNTFATPYYQNPL 182
Query: 692 XFGADIVMYSLTKYMNGHSDVIMGAAIVNDKAIGXKL 802
GADIV +S TKY+ GHSDV+ G N++A+ ++
Sbjct: 183 LLGADIVAHSGTKYLGGHSDVVAGLVTTNNEALAQEI 219
>UniRef50_Q5L1M8 Cluster: Cystathionine beta-lyase; n=42;
Bacteria|Rep: Cystathionine beta-lyase - Geobacillus
kaustophilus
Length = 393
Score = 202 bits (493), Expect = 8e-51
Identities = 96/225 (42%), Positives = 146/225 (64%)
Frame = +2
Query: 128 LKQKPGFATIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPAPAEHTGFEYGRSGNPTRNTL 307
++Q+ F+T +H + ++ + AV PI ++TF Q ++Y RS NPTR L
Sbjct: 1 MEQEWAFSTKLLHNEWKVDR-ETGAVSVPIQHASTFHQFDFDSFGKYDYSRSSNPTREAL 59
Query: 308 EECLAALDGGKYGLTFASXXXXXXXXXXXXNHGDHIVSSDDVYGGTNRLLRQVIARLGIN 487
EE +AAL+GG G FAS + GDH++ ++DVYGGT R++ +V+ R GI
Sbjct: 60 EETIAALEGGTRGFAFASGMAAISTAFLLLSKGDHVLVTEDVYGGTYRMITEVLGRFGIE 119
Query: 488 TTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFL 667
TF D T++ V ++ NTK+I++ETP+NPLLKV DI+ +VK+A++ G + +DNTF+
Sbjct: 120 YTFVDMTDLNAVAENIRPNTKVIYMETPSNPLLKVTDIQGVVKLAKAHG-CLTFLDNTFM 178
Query: 668 TPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVNDKAIGXKL 802
TP LQRPL G D+V++S TK++ GHSDV+ G A+V D+ +G +L
Sbjct: 179 TPALQRPLDLGVDVVLHSATKFLAGHSDVVAGLAVVKDEELGKEL 223
>UniRef50_Q6N7A1 Cluster: Cystathionine gamma-lyase; n=52; cellular
organisms|Rep: Cystathionine gamma-lyase -
Rhodopseudomonas palustris
Length = 390
Score = 201 bits (491), Expect = 1e-50
Identities = 102/226 (45%), Positives = 140/226 (61%), Gaps = 1/226 (0%)
Frame = +2
Query: 128 LKQKPGFATIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPAPAEHTGFEYGRSGNPTRNTL 307
L+Q+ G T A+H GQ + + AV TPI ++TF Q AP H G+EY RS NPTR
Sbjct: 7 LRQR-GANTRAVHGGQHFDP-ATGAVTTPIYATSTFVQSAPGVHKGYEYARSQNPTRAAF 64
Query: 308 EECLAALDGGKYGLTFASXXXXXXXXXXXXNHGDHIVSSDDVYGGTNRLLRQVIAR-LGI 484
E +A + G G FAS G HIV+SDD+YGG+ RL +V + G+
Sbjct: 65 EAAIADAERGHAGFAFASGLAAEAALLEIAGQGSHIVASDDLYGGSWRLFHRVRSHSAGL 124
Query: 485 NTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTF 664
T D N++ +++A+Q NT IWIETP+NP L++ D+EAI I R RG ++ VVDNTF
Sbjct: 125 TITHVDPANLDALRDAIQPNTAFIWIETPSNPTLRLADLEAIAAIGRERG-VLTVVDNTF 183
Query: 665 LTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVNDKAIGXKL 802
+P +QRPL G DIV++S+TKY+ GHSD++ GA +V D + KL
Sbjct: 184 ASPAVQRPLEHGIDIVVHSVTKYIGGHSDIVGGAIVVRDPDLAQKL 229
>UniRef50_Q97M10 Cluster: Cystathionine gamma-synthase; n=15;
Bacteria|Rep: Cystathionine gamma-synthase - Clostridium
acetobutylicum
Length = 384
Score = 200 bits (489), Expect = 2e-50
Identities = 92/219 (42%), Positives = 143/219 (65%)
Frame = +2
Query: 146 FATIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPAPAEHTGFEYGRSGNPTRNTLEECLAA 325
F T A+H G+ + + A+ PI S+TF+ + TG++Y R+GNPTR+ +E+ +AA
Sbjct: 9 FETKAVH-GESGFESRTGAISYPIYQSSTFRHEGLNKGTGYDYSRTGNPTRDEVEKTVAA 67
Query: 326 LDGGKYGLTFASXXXXXXXXXXXXNHGDHIVSSDDVYGGTNRLLRQVIARLGINTTFTDF 505
L+ G+ L ++S GDHI+ SDD+YGGT R+ ++ GI T+TD
Sbjct: 68 LENGRACLAYSSGMAAISSVLTIFKGGDHIIVSDDLYGGTYRIFEEIYEHYGIEVTYTDT 127
Query: 506 TNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQR 685
T+ E ++ ++ENTK I++ETPTNPL+K+ DI + K+A+ + +++VDNTF+TPY Q+
Sbjct: 128 TSTENIEKELRENTKAIYLETPTNPLMKITDIREVSKLAKEH-NTLLIVDNTFMTPYYQK 186
Query: 686 PLXFGADIVMYSLTKYMNGHSDVIMGAAIVNDKAIGXKL 802
PL GADIV++S TKY+ GH+D + G I+ND+ + KL
Sbjct: 187 PLELGADIVLHSGTKYLCGHNDALAGFVILNDERLIEKL 225
>UniRef50_Q8KEI8 Cluster: Trans-sulfuration enzyme family protein;
n=8; Chlorobiaceae|Rep: Trans-sulfuration enzyme family
protein - Chlorobium tepidum
Length = 380
Score = 197 bits (481), Expect = 2e-49
Identities = 97/212 (45%), Positives = 132/212 (62%)
Frame = +2
Query: 146 FATIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPAPAEHTGFEYGRSGNPTRNTLEECLAA 325
F TIAIH G PE + +V P+ ++TF +P+ E F Y R GNPTR+ LE LA
Sbjct: 3 FETIAIHDGNTPESC-TGSVTPPVYQTSTFARPSLDERGEFFYSRIGNPTRSALESTLAL 61
Query: 326 LDGGKYGLTFASXXXXXXXXXXXXNHGDHIVSSDDVYGGTNRLLRQVIARLGINTTFTDF 505
L+ GK+ TFAS GDH+VSS DVYGG+ R+ Q++ G+ T++
Sbjct: 62 LENGKHATTFASGVAAMMAAMQVLKPGDHVVSSLDVYGGSYRIFEQLMRPWGVETSYAAS 121
Query: 506 TNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQR 685
E ++ T+MIWIE+P+NPLL++ DI A+ +IA RG I++ VDNTF +PY QR
Sbjct: 122 EATESYIECIRPETRMIWIESPSNPLLQICDIRALAEIANERG-IVLAVDNTFASPYFQR 180
Query: 686 PLXFGADIVMYSLTKYMNGHSDVIMGAAIVND 781
PL GA IV++S TKY+ GHSDVI GA + +D
Sbjct: 181 PLDLGAHIVVHSTTKYLGGHSDVIGGAVVASD 212
>UniRef50_A6LPZ9 Cluster: Cystathionine gamma-synthase; n=4;
Bacteria|Rep: Cystathionine gamma-synthase - Clostridium
beijerinckii NCIMB 8052
Length = 382
Score = 195 bits (475), Expect = 1e-48
Identities = 95/222 (42%), Positives = 136/222 (61%)
Frame = +2
Query: 137 KPGFATIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPAPAEHTGFEYGRSGNPTRNTLEEC 316
K F TIA+ +K + A+ PI S TFK TG++Y R+ NPTR E+
Sbjct: 4 KKSFETIAVSGVSGGDK-ETGAISFPIYQSATFKHHGLNNSTGYDYARAQNPTREEAEKT 62
Query: 317 LAALDGGKYGLTFASXXXXXXXXXXXXNHGDHIVSSDDVYGGTNRLLRQVIARLGINTTF 496
LA L+GGK + F+S GDHI+ SDD+YGGT RL + G+ TF
Sbjct: 63 LAVLEGGKSAIGFSSGVAAITACIHLFKSGDHIILSDDLYGGTYRLFDDIFRDFGLEATF 122
Query: 497 TDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPY 676
D T + + N+++ENTK I IETP+NP++KV DI+A+ +I ++ ++++VDNTFLTPY
Sbjct: 123 VDTTITKNILNSIKENTKAILIETPSNPMMKVTDIKAVAEITKA-NKLLLIVDNTFLTPY 181
Query: 677 LQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVNDKAIGXKL 802
QRPL GAD+V++S TK++ GH D++ G + ND+ I KL
Sbjct: 182 YQRPLELGADLVVHSGTKFLGGHHDLLAGFIVANDEEILEKL 223
>UniRef50_Q1INQ0 Cluster: Cystathionine gamma-synthase; n=2;
Bacteria|Rep: Cystathionine gamma-synthase -
Acidobacteria bacterium (strain Ellin345)
Length = 385
Score = 194 bits (472), Expect = 3e-48
Identities = 95/224 (42%), Positives = 135/224 (60%)
Frame = +2
Query: 131 KQKPGFATIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPAPAEHTGFEYGRSGNPTRNTLE 310
K+ GF+T +H GQEPE+ + V TST + G+EY R NPTR+ LE
Sbjct: 3 KKDSGFSTKCVHVGQEPEQLTGSVGVPIYATSTYAQDELGKPRLGYEYSRVSNPTRDRLE 62
Query: 311 ECLAALDGGKYGLTFASXXXXXXXXXXXXNHGDHIVSSDDVYGGTNRLLRQVIARLGINT 490
+ LAAL+GG FAS GDH+V S +VYGG RL QV+ G+
Sbjct: 63 KNLAALEGGVDSKVFASGMAAVSAMCSLLKKGDHVVCSSNVYGGVPRLFNQVLVNYGLEF 122
Query: 491 TFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLT 670
T+ D ++++ + A++ +TK ++IETPTNPL+ + DIEAI +IA +G VVVDNTF++
Sbjct: 123 TYVDTSDLKATEKAIRRSTKYVYIETPTNPLMVLSDIEAISQIAHKKG-TEVVVDNTFMS 181
Query: 671 PYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVNDKAIGXKL 802
PY Q+P+ GAD+V++S TK++NGHSD + G + K KL
Sbjct: 182 PYFQKPIALGADMVLHSTTKFLNGHSDGLGGVLVCTTKEQSEKL 225
>UniRef50_Q4A0K3 Cluster: Cystathionine gamma-synthase; n=4;
Bacteria|Rep: Cystathionine gamma-synthase -
Staphylococcus saprophyticus subsp. saprophyticus
(strain ATCC 15305 /DSM 20229)
Length = 381
Score = 191 bits (466), Expect = 2e-47
Identities = 96/218 (44%), Positives = 134/218 (61%), Gaps = 1/218 (0%)
Frame = +2
Query: 152 TIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPAPAE-HTGFEYGRSGNPTRNTLEECLAAL 328
T IH GQ + + + AV TPI ++T+ Q + G+EY RS NPTR+ LE +A L
Sbjct: 5 TQLIHGGQTTDPY-TGAVTTPIYQTSTYMQDGIGDMRQGYEYSRSANPTRSALEGLIADL 63
Query: 329 DGGKYGLTFASXXXXXXXXXXXXNHGDHIVSSDDVYGGTNRLLRQVIARLGINTTFTDFT 508
+ G+ G F S + GDH++ + DVYGGT R L +V R GI+ F D T
Sbjct: 64 EQGESGFAFGSGMAAISAVIMLLDKGDHLLINSDVYGGTYRALTKVFNRFGIDAEFIDTT 123
Query: 509 NIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQRP 688
NIE V+ ++ TKM++IETP+NPLL+V DI+ +IA+ + +I VVDNTF+TPY Q P
Sbjct: 124 NIEAVEQYIKPETKMLYIETPSNPLLRVTDIKKSAEIAK-KHHLISVVDNTFMTPYFQNP 182
Query: 689 LXFGADIVMYSLTKYMNGHSDVIMGAAIVNDKAIGXKL 802
L G DIV++S TKY+ GHSDV+ G +D + +L
Sbjct: 183 LTLGIDIVLHSATKYIGGHSDVVAGLVATSDAELAERL 220
>UniRef50_Q838Z2 Cluster: Cystathionine beta-lyase; n=8;
Bacteria|Rep: Cystathionine beta-lyase - Enterococcus
faecalis (Streptococcus faecalis)
Length = 378
Score = 191 bits (465), Expect = 2e-47
Identities = 93/219 (42%), Positives = 134/219 (61%)
Frame = +2
Query: 146 FATIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPAPAEHTGFEYGRSGNPTRNTLEECLAA 325
F T IH G + + AV PI ++TF+Q + +EY RSGNPTR+ LE +A
Sbjct: 3 FNTKLIHGGISKDT-TTGAVSVPIYQTSTFEQNGVGQPKEYEYSRSGNPTRHALETLIAE 61
Query: 326 LDGGKYGLTFASXXXXXXXXXXXXNHGDHIVSSDDVYGGTNRLLRQVIARLGINTTFTDF 505
L+GG +G F+S DHI+ DDVYGG+ RLL +V G++ T +
Sbjct: 62 LEGGSHGFAFSSGLAGIHAIISMFGPEDHILLGDDVYGGSFRLLDKVFVANGLSYTIVNA 121
Query: 506 TNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQR 685
+++ ++ A+Q NTK +++ETP+NPLLK+ DIEA K+A+ + ++ +VDNTF TPY QR
Sbjct: 122 SDLSTIEAAIQPNTKALFLETPSNPLLKITDIEAAAKLAK-KHQLLTIVDNTFATPYFQR 180
Query: 686 PLXFGADIVMYSLTKYMNGHSDVIMGAAIVNDKAIGXKL 802
PL GADIV++S TKY+ GHSDV+ G + N K+
Sbjct: 181 PLALGADIVVHSGTKYLGGHSDVVSGLVVTNHPESAEKI 219
>UniRef50_Q2IEA5 Cluster: Cystathionine gamma-synthase; n=1;
Anaeromyxobacter dehalogenans 2CP-C|Rep: Cystathionine
gamma-synthase - Anaeromyxobacter dehalogenans (strain
2CP-C)
Length = 426
Score = 189 bits (461), Expect = 6e-47
Identities = 94/224 (41%), Positives = 132/224 (58%)
Frame = +2
Query: 101 KIGMADHGFLKQKPGFATIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPAPAEHTGFEYGR 280
+ G + L G AT +HAG +P+ AV+ PI S+TF + G++Y R
Sbjct: 29 RAGWTERAPLVPGAGLATQCVHAGVQPDP-AYGAVMPPIYQSSTFAFRDVCTNAGYDYTR 87
Query: 281 SGNPTRNTLEECLAALDGGKYGLTFASXXXXXXXXXXXXNHGDHIVSSDDVYGGTNRLLR 460
SGNPTR LEE +A L+GG + HG H++ + D YGGT R L
Sbjct: 88 SGNPTRAALEEAIATLEGGAGATCTTTGMAAVLVALNLLPHGSHLLCTVDCYGGTFRTLE 147
Query: 461 QVIARLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDI 640
G+ T+ D ++ V+ A++ NT M+WIETP+NPLL++ DI A+ ++A RG
Sbjct: 148 HARQAYGLEVTYLDLADLGAVERALRPNTGMVWIETPSNPLLRLTDIRAVTELAHRRG-A 206
Query: 641 IVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAI 772
+VVVDNTFL+P LQRP GAD+V++S TKY+NGHSDV+ GA +
Sbjct: 207 LVVVDNTFLSPALQRPFEHGADLVVHSTTKYLNGHSDVVGGAVV 250
>UniRef50_Q49UL2 Cluster: Cystathionine beta-lyase cystathionine
gamma-synthase; n=16; Staphylococcus|Rep: Cystathionine
beta-lyase cystathionine gamma-synthase - Staphylococcus
saprophyticus subsp. saprophyticus (strain ATCC 15305
/DSM 20229)
Length = 391
Score = 185 bits (451), Expect = 1e-45
Identities = 87/197 (44%), Positives = 123/197 (62%)
Frame = +2
Query: 212 PIVTSTTFKQPAPAEHTGFEYGRSGNPTRNTLEECLAALDGGKYGLTFASXXXXXXXXXX 391
P+ S+TF Q ++Y RSGNP R LEE LA L+GG + +AS
Sbjct: 25 PLYDSSTFHQKTLGGGAQYDYARSGNPNRALLEEKLAKLEGGSHAFAYASGIAAISAVLL 84
Query: 392 XXNHGDHIVSSDDVYGGTNRLLRQVIARLGINTTFTDFTNIEKVKNAMQENTKMIWIETP 571
N GDH++ DDVYGGT RL Q++ R I + D T++ +++ A+Q+NTK+I+IETP
Sbjct: 85 TLNAGDHVILPDDVYGGTFRLTEQILTRFNIQFSTIDTTHLNEIEEAIQDNTKLIYIETP 144
Query: 572 TNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSD 751
+NPL K+ DI IA+ + + + VDNTF+TP Q PL GADIV++S TK+++GH+D
Sbjct: 145 SNPLFKITDIRGAADIAK-KHHLKLAVDNTFMTPLGQSPLALGADIVVHSATKFLSGHTD 203
Query: 752 VIMGAAIVNDKAIGXKL 802
+I G AI ND+ I L
Sbjct: 204 IIAGVAITNDQTIADAL 220
>UniRef50_Q1IQD6 Cluster: Cystathionine gamma-synthase; n=2;
Acidobacteria|Rep: Cystathionine gamma-synthase -
Acidobacteria bacterium (strain Ellin345)
Length = 390
Score = 185 bits (450), Expect = 1e-45
Identities = 94/223 (42%), Positives = 134/223 (60%), Gaps = 1/223 (0%)
Frame = +2
Query: 110 MADHGFLKQKPGFATIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPAPAEHT-GFEYGRSG 286
MAD +K+ GF TIA+HAG+ + ++ AV PI STTF++ + G+ Y R
Sbjct: 4 MADS--IKKSHGFQTIAVHAGRNVDP-STGAVAMPIYPSTTFERDTDGAFSRGYSYIRDA 60
Query: 287 NPTRNTLEECLAALDGGKYGLTFASXXXXXXXXXXXXNHGDHIVSSDDVYGGTNRLLRQV 466
NP R LE CL+AL+ G+ + F+S + GDH+V D+Y G L+ +
Sbjct: 61 NPNRKALEACLSALEVGEEAIAFSSGMGATFSVFQILSPGDHVVLHRDMYYGVRELINGI 120
Query: 467 IARLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIV 646
R GI T D N+++ + A++ TK+ W+ETPTNPL++VV IE I IA G +
Sbjct: 121 FTRYGIQHTVVDMRNLDETRAAVRPGTKLFWLETPTNPLIEVVAIEPIAAIAHEHG-ALF 179
Query: 647 VVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIV 775
+NTF TP LQRPL GAD+V++SLTKY++GHSD + GA I+
Sbjct: 180 ACENTFATPALQRPLELGADLVVHSLTKYLSGHSDAMGGAVIL 222
>UniRef50_A7HF96 Cluster: Cystathionine gamma-synthase; n=7;
Bacteria|Rep: Cystathionine gamma-synthase -
Anaeromyxobacter sp. Fw109-5
Length = 426
Score = 183 bits (446), Expect = 4e-45
Identities = 91/224 (40%), Positives = 130/224 (58%)
Frame = +2
Query: 101 KIGMADHGFLKQKPGFATIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPAPAEHTGFEYGR 280
+ G AD L T +HAG +P+ AV+ PI S+TF + G++Y R
Sbjct: 29 RAGWADRAALVPGAHPGTQCVHAGVQPDP-TYGAVMPPIYQSSTFAFRDVCTNAGYDYTR 87
Query: 281 SGNPTRNTLEECLAALDGGKYGLTFASXXXXXXXXXXXXNHGDHIVSSDDVYGGTNRLLR 460
SGNPTR LEE L L+GG ++ HG H++ + D YGGT R L
Sbjct: 88 SGNPTRAALEEALTILEGGSGATCTSTGMSAVIVALNLLPHGSHLLCTVDCYGGTFRALE 147
Query: 461 QVIARLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDI 640
A G+ T+ D +++ V A + NT+M+WIETP+NPLL++ D+ A+ +AR R D
Sbjct: 148 HAKAAYGLEVTYLDLADLDSVAAAFRPNTRMVWIETPSNPLLRLTDVAAVAALAR-RHDA 206
Query: 641 IVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAI 772
+ VVDNTFL+P Q+P GA++V++S TKY+NGHSDV+ GA +
Sbjct: 207 LTVVDNTFLSPASQQPFRHGAELVVHSTTKYLNGHSDVVGGAVV 250
>UniRef50_P46807 Cluster: Cystathionine gamma-synthase (EC 2.5.1.48)
(CGS) (O-succinylhomoserine (thiol)-lyase); n=42;
cellular organisms|Rep: Cystathionine gamma-synthase (EC
2.5.1.48) (CGS) (O-succinylhomoserine (thiol)-lyase) -
Mycobacterium leprae
Length = 388
Score = 182 bits (444), Expect = 7e-45
Identities = 92/218 (42%), Positives = 134/218 (61%), Gaps = 2/218 (0%)
Frame = +2
Query: 143 GFATIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPAPAE-HTGFEYGRSGNPTRNTLEECL 319
G AT AIHAG P+ + AV PI S+TF Q E GFEY R+GNP R LE L
Sbjct: 13 GLATKAIHAGYRPDP-ATGAVNVPIYASSTFAQDGVGELRGGFEYARTGNPMRAALEASL 71
Query: 320 AALDGGKYGLTFASXXXXXX-XXXXXXNHGDHIVSSDDVYGGTNRLLRQVIARLGINTTF 496
A ++ G + F+S GDH++ DDVYGGT RL+ +V + ++ T
Sbjct: 72 ATVEEGVFARAFSSGMAASDCALRVMLRPGDHVIIPDDVYGGTFRLIDKVFTQWNVDYTP 131
Query: 497 TDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPY 676
++++ V+ A+ T++IW+ETPTNPLL + DI +I ++ + + + V+VDNTF +P
Sbjct: 132 VPLSDLDAVRAAITSRTRLIWVETPTNPLLSIADITSIGELGK-KHSVKVLVDNTFASPA 190
Query: 677 LQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVNDKAI 790
LQ+PL GAD+V++S TKY+ GHSDV+ GA + ND+ +
Sbjct: 191 LQQPLMLGADVVLHSTTKYIGGHSDVVGGALVTNDEEL 228
>UniRef50_A5E0C2 Cluster: Cystathionine gamma-lyase; n=6; cellular
organisms|Rep: Cystathionine gamma-lyase - Lodderomyces
elongisporus (Yeast) (Saccharomyces elongisporus)
Length = 406
Score = 182 bits (442), Expect = 1e-44
Identities = 91/225 (40%), Positives = 134/225 (59%), Gaps = 7/225 (3%)
Frame = +2
Query: 146 FATIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPAPAEHTG-FEYGRSGNPTRNTLEECLA 322
F T A+H G P + AV+ PI STTF Q P++ G +EY RS NP R+ E+ +A
Sbjct: 11 FGTRAVHVGA-PIDATTGAVIEPISLSTTFGQSEPSKPLGIYEYSRSANPNRDNFEQAVA 69
Query: 323 ALDGGKYGLTFASXXXXXXXXXXXXNHGDHIVSSDDVYGGTNRLLRQVIARLGINTTFTD 502
+L+ KY + +S G HI+S DVYGGT+R +V G+ F
Sbjct: 70 SLEQAKYAIALSSGSATTALIIQSLPIGSHIISGGDVYGGTHRYFTKVANHHGVEAQFV- 128
Query: 503 FTNI-EKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGD-----IIVVVDNTF 664
N+ + ++ ++ TK++W+ETP+NP L+V DI + +I ++ D +I+VVDNTF
Sbjct: 129 -ANLADDLEATLRPETKLVWVETPSNPTLQVTDIAKVKQILQNHQDKTGNKVILVVDNTF 187
Query: 665 LTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVNDKAIGXK 799
L+PY+ PL FGAD+V++S+TKY+NGHSDV+MG ND + K
Sbjct: 188 LSPYISNPLKFGADVVVHSVTKYINGHSDVVMGVLATNDSELHEK 232
>UniRef50_Q8XNZ9 Cluster: Cystathionine gamma-synthase; n=7;
Bacteria|Rep: Cystathionine gamma-synthase - Clostridium
perfringens
Length = 384
Score = 180 bits (438), Expect = 4e-44
Identities = 88/218 (40%), Positives = 139/218 (63%), Gaps = 1/218 (0%)
Frame = +2
Query: 152 TIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPAPAEHTGFEYGRSGNPTRNTLEECLAALD 331
++ IH G ++ + AV PI ++T+KQ + E++G+EY R+GNPTR +LE+ +A ++
Sbjct: 5 SLLIHGGISIDE-KTGAVNIPIYQTSTYKQRSFGENSGYEYSRTGNPTRESLEKLIADIE 63
Query: 332 GGKYGLTFASXXXXXXXXXXXXNHGDHIVSSDDVYGGTNRLLRQVIARLGIN-TTFTDFT 508
GK G FAS GD ++ ++++YGGT R++ ++ + GI DFT
Sbjct: 64 YGKRGFAFASGLAAITAVLSLFKSGDKLLITNNLYGGTFRVIDKIFSNFGIGYEIIDDFT 123
Query: 509 NIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQRP 688
NIE+ + ++ K I+IETPTNPLL V+DI+ I + +++ +VDNTF+TPY Q P
Sbjct: 124 NIEE---KIDKSVKAIYIETPTNPLLDVIDIK-IASDKAKKYNLLTIVDNTFMTPYFQNP 179
Query: 689 LXFGADIVMYSLTKYMNGHSDVIMGAAIVNDKAIGXKL 802
L GADIV++S TKY+ GHSD++ G +V D+ +G K+
Sbjct: 180 LNLGADIVIHSATKYLGGHSDLVAGLVVVKDEELGEKI 217
>UniRef50_P53780 Cluster: Cystathionine beta-lyase, chloroplast
precursor; n=11; cellular organisms|Rep: Cystathionine
beta-lyase, chloroplast precursor - Arabidopsis thaliana
(Mouse-ear cress)
Length = 464
Score = 173 bits (421), Expect = 4e-42
Identities = 84/225 (37%), Positives = 138/225 (61%)
Frame = +2
Query: 128 LKQKPGFATIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPAPAEHTGFEYGRSGNPTRNTL 307
+K++ +T+ ++ + + ++ A+ TP+ + TFKQP+ E+ ++Y RSGNPTR+ L
Sbjct: 81 IKEEASVSTLLVNLDNKFDPFD--AMSTPLYQTATFKQPSAIENGPYDYTRSGNPTRDAL 138
Query: 308 EECLAALDGGKYGLTFASXXXXXXXXXXXXNHGDHIVSSDDVYGGTNRLLRQVIARLGIN 487
E LA LD F S +G+ IV+ DDVYGG++RLL QV+ R G+
Sbjct: 139 ESLLAKLDKADRAFCFTSGMAALSAVTHLIKNGEEIVAGDDVYGGSDRLLSQVVPRSGVV 198
Query: 488 TTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFL 667
+ T +++V A+ TK++W+E+PTNP ++ DI I ++A ++G +V+VDN+ +
Sbjct: 199 VKRVNTTKLDEVAAAIGPQTKLVWLESPTNPRQQISDIRKISEMAHAQG-ALVLVDNSIM 257
Query: 668 TPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVNDKAIGXKL 802
+P L RPL GADIVM+S TK++ GHSDV+ G V + + ++
Sbjct: 258 SPVLSRPLELGADIVMHSATKFIAGHSDVMAGVLAVKGEKLAKEV 302
>UniRef50_A7H124 Cluster: Methionine gamma-lyase; n=2;
Campylobacter|Rep: Methionine gamma-lyase -
Campylobacter curvus 525.92
Length = 380
Score = 171 bits (415), Expect = 2e-41
Identities = 87/201 (43%), Positives = 118/201 (58%)
Frame = +2
Query: 200 AVVTPIVTSTTFKQPAPAEHTGFEYGRSGNPTRNTLEECLAALDGGKYGLTFASXXXXXX 379
AVV PIV S+TF Q E F Y RS NPT+ EE A +G KY AS
Sbjct: 20 AVVPPIVLSSTFAQEGLGEFGEFAYSRSANPTKKAFEELFAKFEGSKYSFALASGMAATT 79
Query: 380 XXXXXXNHGDHIVSSDDVYGGTNRLLRQVIARLGINTTFTDFTNIEKVKNAMQENTKMIW 559
GD ++ +++VYGGT R + GI+ D N+ + ++ + ++ KM++
Sbjct: 80 AVFNLLKSGDKVLLNNNVYGGTYRYASGIFKNQGISYELVDDLNLIE-EDDITDDVKMVF 138
Query: 560 IETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMN 739
IETP+NPLL+V DI+ IV +A +G +VVVDNTFLTPY QR L G DIV+YS TKY+
Sbjct: 139 IETPSNPLLRVTDIKRIVNLAHKKG-ALVVVDNTFLTPYYQRLLPLGVDIVVYSATKYIG 197
Query: 740 GHSDVIMGAAIVNDKAIGXKL 802
GH+DVI G ND A+ ++
Sbjct: 198 GHADVIAGIVSTNDDALADRI 218
>UniRef50_Q5MQ31 Cluster: L-methionine-gamma-lyase; n=3;
Micrococcineae|Rep: L-methionine-gamma-lyase -
Brevibacterium linens
Length = 425
Score = 169 bits (410), Expect = 9e-41
Identities = 84/215 (39%), Positives = 124/215 (57%), Gaps = 2/215 (0%)
Frame = +2
Query: 143 GFATIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPAPAE-HTGFEYGRSGNPTRNTLEECL 319
G +T ++H+G PE ++ +VV PI ++TF P + GF+Y R+G P R+ LE+ L
Sbjct: 7 GISTRSVHSGANPES-HTGSVVAPIFQTSTFMMDTPGQTRAGFDYARTGTPNRSDLEDVL 65
Query: 320 AALDGGKYGLTFASXXXXXXXXXXXX-NHGDHIVSSDDVYGGTNRLLRQVIARLGINTTF 496
L+ + S GD I+ D+YGGT RLL+ R GI+
Sbjct: 66 CELENASFAAAVNSGTSAEVAVFSALLGPGDEIIIPRDIYGGTYRLLKNEYERWGISIRT 125
Query: 497 TDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPY 676
D T+ E + A+ T ++W+ETP+NP L +VDI K+A + + I+ VD+TF TP
Sbjct: 126 VDLTDTEALAAAISAKTAIVWVETPSNPGLDIVDIAETAKLAHA-ANAILAVDSTFATPI 184
Query: 677 LQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVND 781
LQRP+ GAD+V++S TK++NGHSDVI GA + D
Sbjct: 185 LQRPIELGADVVIHSTTKFINGHSDVIGGAVLAGD 219
>UniRef50_A3HJ37 Cluster: Cystathionine gamma-lyase; n=7;
Gammaproteobacteria|Rep: Cystathionine gamma-lyase -
Pseudomonas putida (strain GB-1)
Length = 400
Score = 169 bits (410), Expect = 9e-41
Identities = 86/227 (37%), Positives = 138/227 (60%), Gaps = 2/227 (0%)
Frame = +2
Query: 128 LKQKP-GFATIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPAPAEHTGFEYGRSGNPTRNT 304
+ +KP FAT IHAG++ ++A + IVT+++F + + + + Y R GNPTR+
Sbjct: 12 MSEKPRNFATRTIHAGEQFSVADNA-IFPAIVTASSFTKRSLDDKPEYSYSRVGNPTRHA 70
Query: 305 LEECLAALDGGKYGLTFASXXXXXXXXXXXXNHGDHIVSSDDVYGGTNRLLRQVIARL-G 481
E C+AAL+ G + AS H+V + VYGGT R++ +R G
Sbjct: 71 YETCVAALEEGVGAVACASGVNATATVLELLPKDAHVVVMNGVYGGTFRIMEDYRSRTSG 130
Query: 482 INTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNT 661
+ TT+ D ++E V A++ T++IWIE+PTNPLL +VDI+A+ +A++RG I+ +DNT
Sbjct: 131 LTTTYVDLNDLEAVAAAIKPQTQLIWIESPTNPLLHLVDIKAVCDLAKARG-ILTCIDNT 189
Query: 662 FLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVNDKAIGXKL 802
F +P+ QRP+ G D+VM+S +KY+ GHSD+ G + + A+ +L
Sbjct: 190 FCSPWNQRPITLGVDLVMHSASKYIGGHSDLTGGVVVAANDALLARL 236
>UniRef50_Q38DH3 Cluster: Cystathione gamma lyase, putative; n=7;
Trypanosomatidae|Rep: Cystathione gamma lyase, putative
- Trypanosoma brucei
Length = 445
Score = 168 bits (408), Expect = 2e-40
Identities = 86/223 (38%), Positives = 128/223 (57%), Gaps = 3/223 (1%)
Frame = +2
Query: 143 GFATIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPAPA--EHTGFEYGRSGNPTRNTLEEC 316
GF T+ +H G +P+ + AV+TPI STTF Q + + GF Y RS NPT LEE
Sbjct: 59 GFDTLLVHGGVKPDPV-TGAVLTPIYQSTTFVQESIELYQSRGFSYTRSANPTVKALEEK 117
Query: 317 LAALDGGKYGLTFASXXXXXXXXXXXX-NHGDHIVSSDDVYGGTNRLLRQVIARLGINTT 493
L A++ G Y +++ N GDH + +D YGGTNR R R G+ T
Sbjct: 118 LCAVEKGDYATVYSTGMAATTTVVSALMNAGDHAIVTDCSYGGTNRACRVFFTRFGMEFT 177
Query: 494 FTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTP 673
F D ++ V+ A++ NTK++ ETP NP L + DI A+ KI +++G ++ V DNTF T
Sbjct: 178 FVDMRDLSNVEKAIKSNTKLVISETPANPTLTLTDIRALSKICKAKG-LLHVCDNTFATA 236
Query: 674 YLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVNDKAIGXKL 802
++ RP+ GAD+ + S TK+++GH+ + GA + K + KL
Sbjct: 237 FIMRPIDLGADVSLISTTKFVDGHNMTVGGALVTKRKDLDEKL 279
>UniRef50_A0LLP6 Cluster: Cystathionine gamma-synthase; n=1;
Syntrophobacter fumaroxidans MPOB|Rep: Cystathionine
gamma-synthase - Syntrophobacter fumaroxidans (strain
DSM 10017 / MPOB)
Length = 400
Score = 167 bits (407), Expect = 2e-40
Identities = 92/232 (39%), Positives = 134/232 (57%), Gaps = 9/232 (3%)
Frame = +2
Query: 134 QKPGFATIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPAPAEHT--------GFEYGRSGN 289
++ G T AIH G EK + PI ++TF P+ AE G+ Y R N
Sbjct: 9 RRMGKHTKAIHGGGL-EKKVYGEISVPIFQTSTFGFPSAAEGAARFAGESDGYIYTRLNN 67
Query: 290 PTRNTLEECLAALDGGKYGLTFASXXXXXXXXXXXX-NHGDHIVSSDDVYGGTNRLLRQV 466
PT N LEE + L+GG + ++ + GDH+V++D +YG + L+
Sbjct: 68 PTANALEEAMTLLEGGFAAIASSTGMAAVTTTLLTFLSQGDHVVATDSIYGASRMALQFE 127
Query: 467 IARLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIV 646
AR GI TF D ++ ++ A+ NTK+I++ETPTNP + V DI A ++AR+RG I+
Sbjct: 128 FARFGIGATFVDSSSTANIERAIGRNTKVIFLETPTNPTMAVSDIRAAAELARARG-AIL 186
Query: 647 VVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVNDKAIGXKL 802
VVDNTF PYLQRPL GADIV+ SLTK++NGHSDV+ G + ++ + ++
Sbjct: 187 VVDNTFAGPYLQRPLELGADIVVESLTKFINGHSDVLGGMVVTRNEELHAQI 238
>UniRef50_Q8KNG3 Cluster: CalE6; n=2; Micromonosporaceae|Rep: CalE6
- Micromonospora echinospora (Micromonospora purpurea)
Length = 381
Score = 167 bits (405), Expect = 4e-40
Identities = 91/213 (42%), Positives = 122/213 (57%), Gaps = 1/213 (0%)
Frame = +2
Query: 146 FATIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPAPAEHTGFEYGRSGNPTRNTLEECLAA 325
F T +H G+ P + VV PI STT+++ A E F YGR NPTR LEECLA
Sbjct: 6 FDTRLVHGGRRPSA-GTGDVVPPIHVSTTYERRAQDEPRYF-YGRGENPTREELEECLAG 63
Query: 326 LDGGKYGLTFASXXXXXXXXXXXXNHGDHIVSSDDVYGGTNRLLRQVIARLGINTTFTDF 505
L+ + F+S G +VS+DDVY GT+ L + AR G+ + D
Sbjct: 64 LERAPFATVFSSGQAAAATLLSLVRPGQCVVSTDDVYAGTDGLF-DLAARQGVRVRYADL 122
Query: 506 TNIEKVKNAMQE-NTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQ 682
T E + A+ E + ++WIETPTNPLL VVD+ + + A RG VVVDNTF +P LQ
Sbjct: 123 TTPEGIAAALAEPDLALVWIETPTNPLLTVVDVAEVSRRAHERG-ARVVVDNTFASPVLQ 181
Query: 683 RPLXFGADIVMYSLTKYMNGHSDVIMGAAIVND 781
+PL GAD+ +YS TK + GH+DV+ GA + D
Sbjct: 182 QPLALGADVSLYSTTKSIAGHADVLGGALVYRD 214
>UniRef50_A6X770 Cluster: Cystathionine gamma-synthase; n=1;
Ochrobactrum anthropi ATCC 49188|Rep: Cystathionine
gamma-synthase - Ochrobactrum anthropi (strain ATCC
49188 / DSM 6882 / NCTC 12168)
Length = 398
Score = 162 bits (393), Expect = 1e-38
Identities = 84/221 (38%), Positives = 123/221 (55%), Gaps = 2/221 (0%)
Frame = +2
Query: 131 KQKPGFATIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPAPAEHTGFEYGRSGNPTRNTLE 310
+ + GFAT AIH GQEP+ + AV+ PI +TT+ Q G++Y RSGNPTRN LE
Sbjct: 7 RNQAGFATRAIHVGQEPDPL-TGAVIPPIYHATTYVQDGIGASKGYDYTRSGNPTRNGLE 65
Query: 311 ECLAALDGGKYGLTFASXXXXXXXXXXXXNHGDHIVSSDDVYGGTNRLLRQV-IARLGIN 487
CLA L+G F S G I++ +D+YGG RLL V N
Sbjct: 66 RCLADLEGAAAAFVFPSGLAAAATLLEALPAGSSILAHNDLYGGVYRLLADVRPVTAAHN 125
Query: 488 TTFTDFTNIEKVKNA-MQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTF 664
F DF++ ++ A + ++W ETP+NP L++VD+ + ++ + G I V D+TF
Sbjct: 126 VNFVDFSDEAALRQAVLDHKPALLWFETPSNPTLRIVDLSLVAELGKQAG-AITVCDSTF 184
Query: 665 LTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVNDKA 787
+P QRP+ G +V++S TK +NGHSD++ G V+ A
Sbjct: 185 SSPAGQRPIDHGIHVVVHSATKMLNGHSDLLGGVVAVSANA 225
>UniRef50_Q8R9N2 Cluster: Cystathionine beta-lyases/cystathionine
gamma-synthases; n=4; Bacteria|Rep: Cystathionine
beta-lyases/cystathionine gamma-synthases -
Thermoanaerobacter tengcongensis
Length = 393
Score = 161 bits (392), Expect = 1e-38
Identities = 81/176 (46%), Positives = 112/176 (63%), Gaps = 1/176 (0%)
Frame = +2
Query: 266 FEYGRSGNPTRNTLEECLAALDGGKYGLTFASXXXXXXXXXXXX-NHGDHIVSSDDVYGG 442
+ Y R GNP + +EE +A L+G + G AS N GDHI+++ D+YGG
Sbjct: 54 YMYTRLGNPNQTAVEELIANLEGAEAGQACASGMAAISSALLAEVNSGDHIIAAKDIYGG 113
Query: 443 TNRLLRQVIARLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIA 622
TN L RLGI + DF+++E V+ A++ NTK+I++E TNPL++V DIE +VKIA
Sbjct: 114 TNSLFNLEFKRLGIEISLVDFSDLESVEKAIKPNTKVIYMEIMTNPLIRVFDIEEVVKIA 173
Query: 623 RSRGDIIVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVNDKAI 790
+ G + ++VDNTF TPYL RPL GA V++S TKY+NGHSDVI G N + I
Sbjct: 174 KRHG-LKLIVDNTFTTPYLIRPLEVGAYAVIHSATKYINGHSDVIGGLIAGNKEFI 228
>UniRef50_Q12L75 Cluster: Methionine gamma-lyase; n=1; Shewanella
denitrificans OS217|Rep: Methionine gamma-lyase -
Shewanella denitrificans (strain OS217 / ATCC BAA-1090 /
DSM 15013)
Length = 390
Score = 161 bits (392), Expect = 1e-38
Identities = 86/221 (38%), Positives = 129/221 (58%), Gaps = 9/221 (4%)
Frame = +2
Query: 149 ATIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPAP--------AEHTGFEYGRSGNPTRNT 304
AT+AIH G + E + A+VTP+ S TF + G+ Y R GNPT
Sbjct: 8 ATVAIHGGHQREAFG--ALVTPLYQSATFAFETAEQGGARFAGDEPGYIYTRLGNPTTAE 65
Query: 305 LEECLAALDGGKYGLTFASXXXXXXXXXXXX-NHGDHIVSSDDVYGGTNRLLRQVIARLG 481
LE +A L+G AS GDH+++S VYG T L+ ++R G
Sbjct: 66 LERKMALLEGADDAAATASGMAAVSAALLTHLEQGDHLIASKAVYGCTYALITTQLSRYG 125
Query: 482 INTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNT 661
I+T+ DF++++ V+ A++ NT++++ ETP NP L+V D++A+ K+A+ G +I +VDNT
Sbjct: 126 ISTSLVDFSDMQAVEAAIKPNTRVLFCETPVNPHLQVFDLDAMAKVAKKHG-LISIVDNT 184
Query: 662 FLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVNDK 784
F+TP LQ+PL G D+V++S TKY+NGH DVI G N +
Sbjct: 185 FMTPLLQKPLAMGIDMVIHSATKYLNGHGDVIAGIVCGNSE 225
>UniRef50_A6YH84 Cluster: Cystathionine gamma-synthase; n=2;
Lactobacillus casei|Rep: Cystathionine gamma-synthase -
Lactobacillus casei
Length = 378
Score = 161 bits (392), Expect = 1e-38
Identities = 83/219 (37%), Positives = 124/219 (56%)
Frame = +2
Query: 146 FATIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPAPAEHTGFEYGRSGNPTRNTLEECLAA 325
F T +H G + + + A+V P+ S ++ + ++Y RS NPTR+ LE +A
Sbjct: 4 FNTKLVH-GPQLQTDKAGAIVPPVYQSAMYRFAPDGGTSDWDYARSSNPTRDYLERQIAT 62
Query: 326 LDGGKYGLTFASXXXXXXXXXXXXNHGDHIVSSDDVYGGTNRLLRQVIARLGINTTFTDF 505
L+ G G F+S G H + D +Y GT+RLL Q A+ G+ T D
Sbjct: 63 LENGDAGFAFSSGVAAIATVLAIFPDGSHFIIGDSLYSGTDRLLNQYFAQHGLTFTPVDP 122
Query: 506 TNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQR 685
++ V+ A++ TK I+ ET +NPLLKV ++AI +A++ D++ +VDNTFLTPY QR
Sbjct: 123 RDLTAVEAAIRPETKAIFFETFSNPLLKVSSVKAISTLAKAH-DLLTIVDNTFLTPYYQR 181
Query: 686 PLXFGADIVMYSLTKYMNGHSDVIMGAAIVNDKAIGXKL 802
PL GADIV++S TKY+ GH D+I G + I K+
Sbjct: 182 PLDLGADIVLHSATKYIGGHGDLIAGLVVSASPEISEKI 220
>UniRef50_Q96VU8 Cluster: Cystathionine beta-lyase; n=3;
Pezizomycotina|Rep: Cystathionine beta-lyase -
Neurospora crassa
Length = 457
Score = 161 bits (392), Expect = 1e-38
Identities = 83/198 (41%), Positives = 112/198 (56%), Gaps = 1/198 (0%)
Frame = +2
Query: 212 PIVTSTTFKQPAPAEHTGFEYGRSGNPTRNTLEECLAALDGGKYGLTFASXXXXXXXXXX 391
PI S TFKQ + + ++Y RSGNPTR LE LA + L+ +S
Sbjct: 64 PIYQSATFKQSSSNGGSEYDYTRSGNPTRTHLERHLAKIMNANRCLSVSSGMGALDVITR 123
Query: 392 XXNHGDHIVSSDDVYGGTNRLLRQVIARLGINTTFTDFTNIEKVKNAMQENTKMIWIETP 571
GD +++ DD+YGGTNRLL + G+ D TN+E V+ + T M+ +ETP
Sbjct: 124 LLKPGDEVITGDDLYGGTNRLLTYLKNNQGVIVHHVDTTNVESVRQIISPKTTMVLLETP 183
Query: 572 TNPLLKVVDIEAIVKIARSRGD-IIVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHS 748
TNPL+K+ DI I +I + +VVVDNT L+P L PL GADIV S TKY++GH
Sbjct: 184 TNPLIKICDIPTIARITHEANEKAVVVVDNTMLSPMLFNPLDVGADIVYESGTKYLSGHH 243
Query: 749 DVIMGAAIVNDKAIGXKL 802
D++ G VND +G KL
Sbjct: 244 DIMAGVIAVNDTELGDKL 261
>UniRef50_A5GJ98 Cluster: MetC/metB Cystathionine
beta-lyase/cystathioninegamma-synthase; n=21;
Cyanobacteria|Rep: MetC/metB Cystathionine
beta-lyase/cystathioninegamma-synthase - Synechococcus
sp. (strain WH7803)
Length = 393
Score = 161 bits (391), Expect = 2e-38
Identities = 83/209 (39%), Positives = 119/209 (56%)
Frame = +2
Query: 140 PGFATIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPAPAEHTGFEYGRSGNPTRNTLEECL 319
P AT+AIH G+ + V+ PI ++TF P GF+Y RSGNP LE L
Sbjct: 16 PADATLAIHHGESFAD-GTGTVMPPIYATSTFAHGNPG---GFDYTRSGNPNFRILEGVL 71
Query: 320 AALDGGKYGLTFASXXXXXXXXXXXXNHGDHIVSSDDVYGGTNRLLRQVIARLGINTTFT 499
A+++ + F S GD ++ +++YG T RL QV A+ G+ T +
Sbjct: 72 ASVERCDHATVFGSGVSAITAIASTLQQGDLVLCEENLYGCTVRLFEQVFAKFGVRTEWV 131
Query: 500 DFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYL 679
DFT+ + ++ M+W+E+PTNPLLKV+D+EA+ AR ++ VVVDNTF T +
Sbjct: 132 DFTDPSALTAIVERQPAMVWLESPTNPLLKVIDLEAVCSAARG-AEVPVVVDNTFATALV 190
Query: 680 QRPLXFGADIVMYSLTKYMNGHSDVIMGA 766
QRPL GA + + S TKY+NGHSD + GA
Sbjct: 191 QRPLQLGATLSLTSTTKYINGHSDALGGA 219
>UniRef50_Q5UZS6 Cluster: Cystathionine gamma-synthase; n=3;
cellular organisms|Rep: Cystathionine gamma-synthase -
Haloarcula marismortui (Halobacterium marismortui)
Length = 411
Score = 161 bits (391), Expect = 2e-38
Identities = 78/181 (43%), Positives = 112/181 (61%), Gaps = 2/181 (1%)
Frame = +2
Query: 266 FEYGRSGNPTRNTLEECLAALDGGKYGLTFASXXXXXXXXXXXX-NHGDHIVSSDDVYGG 442
F Y R NPTR+ LE+ LAAL+GG+ F+S GDH+V+ DD+Y G
Sbjct: 68 FLYSRLSNPTRHGLEQELAALEGGERAYAFSSGTAAVATAVLSLVEPGDHVVAFDDLYAG 127
Query: 443 TNRLLRQVIA-RLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKI 619
T R+ + +LG++ F D T+ + V AM T+++W+ETPTNP +K+ DI+AI +
Sbjct: 128 TRRMFETLFRDQLGVDVEFVDATDADAVAAAMTPATELVWVETPTNPRIKLCDIDAIAAV 187
Query: 620 ARSRGDIIVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVNDKAIGXK 799
A D V VDNTF +PY Q+PL GAD+V++S TKY+NGHSD + GA I +D + +
Sbjct: 188 AADY-DATVGVDNTFASPYFQQPLSLGADLVVHSTTKYLNGHSDAVGGALITDDPEVAER 246
Query: 800 L 802
+
Sbjct: 247 V 247
>UniRef50_Q8TMW7 Cluster: Methionine gamma-lyase; n=3;
Methanosarcina|Rep: Methionine gamma-lyase -
Methanosarcina acetivorans
Length = 406
Score = 161 bits (390), Expect = 2e-38
Identities = 89/220 (40%), Positives = 130/220 (59%), Gaps = 11/220 (5%)
Frame = +2
Query: 146 FATIAIHAGQEPEKWNSAAVVTPIVTSTTF-----KQPAP---AEHTGFEYGR--SGNPT 295
FAT +HAG+EP+ A TPI ++TF +Q A E +G+ Y R PT
Sbjct: 7 FATKCVHAGEEPDPVFGAHT-TPIFQTSTFIFKNVEQGAARFAGEESGYVYTRIPPNTPT 65
Query: 296 RNTLEECLAALDGGKYGLTFASXXXXXXXXXXXX-NHGDHIVSSDDVYGGTNRLLRQVIA 472
L E +A L+GG+ G TFAS GDH++S+D VYG T L +++
Sbjct: 66 HAVLAEKVAVLEGGEAGQTFASGMAAITAVVLSTLKQGDHLISTDVVYGCTYSLFSEILP 125
Query: 473 RLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVV 652
GI+ +F D ++I+KV+ A + T+M+++ETP NP + V DI I K+A+++G I +V
Sbjct: 126 GFGIDVSFVDTSDIKKVRAAFKPETRMVFLETPANPTITVCDIREISKLAKAQG-AICIV 184
Query: 653 DNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAI 772
DNTF TPY Q+PL GADI + S TKY+ GH+D++ G +
Sbjct: 185 DNTFATPYFQKPLELGADISLSSCTKYIGGHADLLGGIVV 224
>UniRef50_A0NJV2 Cluster: O-succinylhomoserine thiol-lyase; n=2;
Leuconostocaceae|Rep: O-succinylhomoserine thiol-lyase -
Oenococcus oeni ATCC BAA-1163
Length = 369
Score = 160 bits (388), Expect = 4e-38
Identities = 77/219 (35%), Positives = 122/219 (55%), Gaps = 2/219 (0%)
Frame = +2
Query: 152 TIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPAPAEHTGFEYGRSGNPTRNTLEECLAALD 331
TI G + + AVV PI ST F+ P E TGF+Y R PTR LE+ LA ++
Sbjct: 6 TILDQGGNGSDDQKTGAVVAPIYFSTAFRHPGLGESTGFDYARLQTPTRQILEKQLAEIE 65
Query: 332 GGKYGLTFASXXXXXXXXXXXX-NHGDHIVSSDDVYGGTNRLLRQVIARLGINTTFTDFT 508
G +S GD+ ++SDD+YGG+ R ++ + GI+ + D T
Sbjct: 66 YGDNAFAVSSGMAAIDLLFSTFLKKGDNFIASDDLYGGSFRYFDDLVEKNGIDYSLWDGT 125
Query: 509 NIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVK-IARSRGDIIVVVDNTFLTPYLQR 685
+ +K + T++IW+ETP+NP +K++DI+ + + + I+V VDNTFL+P LQ
Sbjct: 126 DFSYLKQKISPKTRLIWLETPSNPTMKIIDIKKVADFVHKIDSKILVAVDNTFLSPILQN 185
Query: 686 PLXFGADIVMYSLTKYMNGHSDVIMGAAIVNDKAIGXKL 802
P+ GAD+V++S TKY+ GH+D++ G + + + L
Sbjct: 186 PIKLGADLVVHSATKYLGGHNDILAGVVVSSRSELSKSL 224
>UniRef50_Q9K024 Cluster: Cystathionine gamma-synthase; n=4;
Neisseria|Rep: Cystathionine gamma-synthase - Neisseria
meningitidis serogroup B
Length = 385
Score = 159 bits (387), Expect = 6e-38
Identities = 84/221 (38%), Positives = 125/221 (56%), Gaps = 2/221 (0%)
Frame = +2
Query: 146 FATIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPAPAEHTGFEYGRSGNPTRNTLEECLAA 325
FAT AIH+ + ++ N A ++ PI ++ F E+ + Y R NPTR LE+ +A
Sbjct: 3 FATKAIHSSYDCDEHNRA-LMPPIYQNSMFALHEIGENVPYRYSRLSNPTRQILEDTVAD 61
Query: 326 LDGGKYGLTFASXXXXXXXX-XXXXNHGDHIVSSDDVYGGTNRLLRQVIARLGINTTFTD 502
L+ G G F+S GD IV+ D+YGG LL V + G+N F D
Sbjct: 62 LEHGAAGFAFSSGMAGIDAVWRTFLRPGDTIVAVADIYGGAYDLLVDVYQKWGVNVVFAD 121
Query: 503 FTNIEKVKNAMQEN-TKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYL 679
N + + ++ + K++W+ETP+NPLL++VDI+ + A++ G +V +DNTF TPYL
Sbjct: 122 LGNPDNLDELLKAHKVKLVWLETPSNPLLRLVDIKVLAAKAKAAG-ALVGIDNTFATPYL 180
Query: 680 QRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVNDKAIGXKL 802
Q+PL G D V +S TKY+ GHSDV+MG + K + L
Sbjct: 181 QQPLDMGCDFVFHSATKYLCGHSDVLMGIVVAKTKELAQPL 221
>UniRef50_Q67R76 Cluster: Cystathionine gamma-lyase; n=13;
Bacteria|Rep: Cystathionine gamma-lyase -
Symbiobacterium thermophilum
Length = 401
Score = 159 bits (387), Expect = 6e-38
Identities = 88/222 (39%), Positives = 128/222 (57%), Gaps = 9/222 (4%)
Frame = +2
Query: 134 QKPGFATIAIHAGQEPEKWNSAAVVTPIVTSTTF-----KQPAP---AEHTGFEYGRSGN 289
++PG AT +HAGQ P+ + A+ PI ++TF +Q A E G+ Y R GN
Sbjct: 5 RQPGLATRCVHAGQRPDPL-TGAISPPIYQTSTFAFASLEQGAARFAGEEPGYIYTRLGN 63
Query: 290 PTRNTLEECLAALDGGKYGLTFASXXXXXXXXXXXX-NHGDHIVSSDDVYGGTNRLLRQV 466
PT LE +A L+GG+ + F S GDH++ + +YG T L V
Sbjct: 64 PTVAALEAKIADLEGGEAAVAFGSGMAAIAAVVTALVRAGDHVLFGNPIYGCTYDFLMDV 123
Query: 467 IARLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIV 646
+AR G+ T D +V+ A++ NT+++ ETP NP L++ DI A+ +A R I V
Sbjct: 124 MARFGVEATPVDPARPGQVERAIRPNTRLLLFETPANPTLRLADIRALSDLAH-RHQITV 182
Query: 647 VVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAI 772
VVDNTF++PYLQRPL GAD+V++S TK++ GH DV+ G A+
Sbjct: 183 VVDNTFMSPYLQRPLEHGADMVVHSATKFIGGHGDVVAGLAV 224
>UniRef50_Q9KEQ0 Cluster: Methionine gamma lyase; n=13;
Bacillaceae|Rep: Methionine gamma lyase - Bacillus
halodurans
Length = 393
Score = 159 bits (385), Expect = 1e-37
Identities = 84/228 (36%), Positives = 132/228 (57%), Gaps = 9/228 (3%)
Frame = +2
Query: 128 LKQKPGFATIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPA--------PAEHTGFEYGRS 283
+K+ F T AIH G +P + + ++ PI ++TF + E G+ Y R
Sbjct: 1 MKRDQHFETRAIHTGYKPNE-HFDSLTPPIYQTSTFTFASMEQGGNRFAGEEAGYVYSRL 59
Query: 284 GNPTRNTLEECLAALDGGKYGLTFASXXXXXXXXXXXXNHG-DHIVSSDDVYGGTNRLLR 460
GNPT LE+ +A L+GG+ L F S DHI+ S+ VYG T LL
Sbjct: 60 GNPTVQILEQRIAELEGGEAALAFGSGMAAVSAILVGLTKANDHILVSNGVYGCTFGLLT 119
Query: 461 QVIARLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDI 640
+ + I+ TF+ ++E++ +Q+NT I++ETP NP ++++D+E +V++A+ +G I
Sbjct: 120 MLKEKYNIDATFSPMDSVEEILANIQDNTTCIYVETPINPTMQLIDLELVVRVAKEKG-I 178
Query: 641 IVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVNDK 784
V+VDNTF TPYLQ+P+ G D V++S TKY+ GH DV+ G ++ DK
Sbjct: 179 KVIVDNTFATPYLQQPIALGCDFVVHSATKYIGGHGDVVAG-VLIGDK 225
>UniRef50_Q0LLX7 Cluster: Cystathionine gamma-synthase; n=3;
Bacteria|Rep: Cystathionine gamma-synthase -
Herpetosiphon aurantiacus ATCC 23779
Length = 372
Score = 158 bits (384), Expect = 1e-37
Identities = 85/208 (40%), Positives = 120/208 (57%), Gaps = 1/208 (0%)
Frame = +2
Query: 152 TIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPAPAEHT-GFEYGRSGNPTRNTLEECLAAL 328
T+ IHAG+ + SA V PI ++TF++ A GF Y R GNPTR LE+ LAAL
Sbjct: 5 TLLIHAGRSVDAATSA-VTPPIHLASTFERAADGSLPHGFVYTRFGNPTRQALEQALAAL 63
Query: 329 DGGKYGLTFASXXXXXXXXXXXXNHGDHIVSSDDVYGGTNRLLRQVIARLGINTTFTDFT 508
+GG F S G ++ D Y GT L+RQV A+L + F D T
Sbjct: 64 EGGVEAAAFGSGSAATTAVLQSLAPGQRVLLPRDCYNGTANLVRQVFAQL--DAQFVDMT 121
Query: 509 NIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQRP 688
++ V+ A++ ++W+ETP+NP L++ D+ A+ +A + G +VV DNT+ TP QRP
Sbjct: 122 DLAAVQAALEPAPALVWLETPSNPTLRLTDLAAVSNLAHAVG-ALVVCDNTWATPLGQRP 180
Query: 689 LXFGADIVMYSLTKYMNGHSDVIMGAAI 772
G D+VM+S TKY+ GHSDV+ GA I
Sbjct: 181 FDLGVDLVMHSTTKYLGGHSDVLGGALI 208
>UniRef50_Q9KCE4 Cluster: Cystathionine gamma-synthase
(O-succinylhomoserine (Thiol)-lyase); n=44;
Bacteria|Rep: Cystathionine gamma-synthase
(O-succinylhomoserine (Thiol)-lyase) - Bacillus
halodurans
Length = 378
Score = 158 bits (383), Expect = 2e-37
Identities = 72/199 (36%), Positives = 117/199 (58%)
Frame = +2
Query: 194 SAAVVTPIVTSTTFKQPAPAEHTGFEYGRSGNPTRNTLEECLAALDGGKYGLTFASXXXX 373
+ A+ TP+ ST ++ E TG++Y R+GNPTR LE+ +A L+ G G +S
Sbjct: 21 TGAINTPVYFSTAYRHSGIGESTGYDYARTGNPTREVLEKAIATLENGDQGFACSSGMAA 80
Query: 374 XXXXXXXXNHGDHIVSSDDVYGGTNRLLRQVIARLGINTTFTDFTNIEKVKNAMQENTKM 553
GD I++S D+YGGT RL + G++ ++ D N+ ++ + E T+
Sbjct: 81 IQTVFSLFQSGDEIIASQDLYGGTYRLFEGGWKKWGLSFSYADPRNLAALEQQITEKTRA 140
Query: 554 IWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQRPLXFGADIVMYSLTKY 733
++IETPTNPL++ +I + +A G ++++VDNTF TP LQ+PL G IV++S +KY
Sbjct: 141 LFIETPTNPLMQEANIRELAALANKHG-LLLIVDNTFYTPLLQQPLNEGTHIVIHSASKY 199
Query: 734 MNGHSDVIMGAAIVNDKAI 790
+ GH+DVI G + + +
Sbjct: 200 LGGHNDVIAGLIVAKGQEL 218
>UniRef50_Q2AGF7 Cluster: O-acetylhomoserine/O-acetylserine
sulfhydrylase; n=1; Halothermothrix orenii H 168|Rep:
O-acetylhomoserine/O-acetylserine sulfhydrylase -
Halothermothrix orenii H 168
Length = 397
Score = 158 bits (383), Expect = 2e-37
Identities = 87/224 (38%), Positives = 128/224 (57%), Gaps = 10/224 (4%)
Frame = +2
Query: 131 KQKPGFATIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPAPAEHT---------GFEYGRS 283
K++ GF T+A+H G +P + S + PI +T++ + AEH G+ Y R
Sbjct: 6 KKQYGFNTLALHHGYDPVQEGSKSRAVPIYQTTSYMFDS-AEHAAGLFAEEEEGYIYTRI 64
Query: 284 GNPTRNTLEECLAALDGGKYGL-TFASXXXXXXXXXXXXNHGDHIVSSDDVYGGTNRLLR 460
GNPT EE +A L+GG+ GL T + + G+ +VSS +YGGT LL
Sbjct: 65 GNPTTKVFEERMAVLEGGEAGLATSSGQSAITLTILTLVSQGEEVVSSSYIYGGTYHLLA 124
Query: 461 QVIARLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDI 640
+ + R G+ T F +I + A+ + T++ ++E+P NP L +VDIEA+ +A G I
Sbjct: 125 ESLPRYGVKTRFVKPDDINDWEQAITDKTRVFYLESPGNPRLNIVDIEAVSSLAHQYG-I 183
Query: 641 IVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAI 772
VVVDNTF TPYL +PL GADIV++S TKY+ GH + I G +
Sbjct: 184 TVVVDNTFNTPYLSQPLKLGADIVVHSTTKYIGGHGNSIGGVIV 227
>UniRef50_P13254 Cluster: Methionine gamma-lyase; n=33; cellular
organisms|Rep: Methionine gamma-lyase - Pseudomonas
putida
Length = 398
Score = 157 bits (380), Expect = 4e-37
Identities = 87/227 (38%), Positives = 122/227 (53%), Gaps = 9/227 (3%)
Frame = +2
Query: 119 HGFLKQKPGFATIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPA--------PAEHTGFEY 274
HG K PGFAT AIH G +P+ + A+V P+ + TF P E G Y
Sbjct: 2 HGSNKL-PGFATRAIHHGYDPQD-HGGALVPPVYQTATFTFPTVEYGAACFAGEQAGHFY 59
Query: 275 GRSGNPTRNTLEECLAALDGGKYGLTFASXXXXXXXXX-XXXNHGDHIVSSDDVYGGTNR 451
R NPT N LE +A+L+GG+ GL AS GD ++ + +YG T
Sbjct: 60 SRISNPTLNLLEARMASLEGGEAGLALASGMGAITSTLWTLLRPGDEVLLGNTLYGCTFA 119
Query: 452 LLRQVIARLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSR 631
L I G+ D +++ ++ AM T++I+ E+P NP + + DI + KIAR
Sbjct: 120 FLHHGIGEFGVKLRHVDMADLQALEAAMTPATRVIYFESPANPNMHMADIAGVAKIARKH 179
Query: 632 GDIIVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAI 772
G VVVDNT+ TPYLQRPL GAD+V++S TKY++GH D+ G +
Sbjct: 180 G-ATVVVDNTYCTPYLQRPLELGADLVVHSATKYLSGHGDITAGIVV 225
>UniRef50_Q8G436 Cluster: Possible cystathionine gamma lyase; n=3;
Bacteria|Rep: Possible cystathionine gamma lyase -
Bifidobacterium longum
Length = 507
Score = 156 bits (379), Expect = 5e-37
Identities = 95/237 (40%), Positives = 127/237 (53%), Gaps = 11/237 (4%)
Frame = +2
Query: 110 MADHG--FLKQKPGFATIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPAPAEHTGFE---- 271
+ HG F Q GF T+AIH G + + A+ PI + + P +
Sbjct: 102 LVHHGQSFDDQPLGFGTLAIHLGNGVDA-ETGAIRRPITLANAYALPYDPSDINWSSSDV 160
Query: 272 --YGRSGNPTRNTLEECLAALDGGKYGLTFASXXXXXXXXXXXX-NHGDHIVSSDDVYGG 442
Y R+G+P + LEE LA L+G + + AS N GDH + SD Y
Sbjct: 161 NLYTRNGHPNQRYLEEKLARLEGAEDAVVLASGVAALAATFTTFLNRGDHAIFSDTTYIA 220
Query: 443 TNRLLRQVIA-RLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKI 619
RLL Q++ + GI T+ D ++ E V+ A++ NTK++ IETP NP LKV DI I K+
Sbjct: 221 AYRLLNQILPEKYGIETSILDTSDPENVRAALRPNTKLVHIETPANPTLKVSDIATIAKL 280
Query: 620 ARSRG-DIIVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVNDKA 787
A DI+V VDNTF TPY RPL GADIV+ SLTKY+NGH D +G +I KA
Sbjct: 281 AHEANPDILVSVDNTFNTPYNVRPLNLGADIVIESLTKYINGHGDA-LGGSIATTKA 336
>UniRef50_Q1J8Q9 Cluster: Cystathionine beta-lyase; n=14;
Bacilli|Rep: Cystathionine beta-lyase - Streptococcus
pyogenes serotype M4 (strain MGAS10750)
Length = 463
Score = 156 bits (379), Expect = 5e-37
Identities = 80/217 (36%), Positives = 121/217 (55%)
Frame = +2
Query: 152 TIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPAPAEHTGFEYGRSGNPTRNTLEECLAALD 331
T +H +++ AA V TST Y R NPT LE+ LA L+
Sbjct: 89 TTLLHGYTVIDEFTGAASVPIYQTSTFHNSELYCPSQKHLYTRFSNPTTEALEDGLACLE 148
Query: 332 GGKYGLTFASXXXXXXXXXXXXNHGDHIVSSDDVYGGTNRLLRQVIARLGINTTFTDFTN 511
Y + +AS GDH++ +VYGGT + ++ I T+F D +
Sbjct: 149 KATYAVAYASGMAAISTVLMLLKAGDHVIFPLEVYGGTCQFATAILPNYQIETSFVDMAD 208
Query: 512 IEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQRPL 691
+ VK +++ NT+MI++ETP+NPLLK+ DI +V++A++ G ++ V DNTF+T Q PL
Sbjct: 209 LATVKASIRPNTRMIYLETPSNPLLKICDISELVQLAKAYG-VLTVADNTFMTSLYQEPL 267
Query: 692 XFGADIVMYSLTKYMNGHSDVIMGAAIVNDKAIGXKL 802
G DIV+ S+TK++NGHSDV+ G A N++AI +L
Sbjct: 268 AMGVDIVVESVTKFINGHSDVVAGLAATNNEAIYNQL 304
>UniRef50_Q89V23 Cluster: O-acetylhomoserine sulfhydrylase; n=13;
Bacteria|Rep: O-acetylhomoserine sulfhydrylase -
Bradyrhizobium japonicum
Length = 431
Score = 155 bits (376), Expect = 1e-36
Identities = 92/220 (41%), Positives = 123/220 (55%), Gaps = 9/220 (4%)
Frame = +2
Query: 140 PGFATIAIHAGQEPEKWNSAAVVTPIVTSTTF----KQPAPA----EHTGFEYGRSGNPT 295
P F T+++HAGQ P+ A V PI +T++ A A E G Y R NPT
Sbjct: 7 PAFETLSLHAGQHPDPATGARAV-PIYQTTSYVFQDSDHAAALFNLERAGHIYTRISNPT 65
Query: 296 RNTLEECLAALDGGKYGLTFASXXXXXXXXXXXX-NHGDHIVSSDDVYGGTNRLLRQVIA 472
LEE LAAL+GG + AS N GDHIV+S +YGGT LL +
Sbjct: 66 TGVLEERLAALEGGVGAICTASGMAALHLAIATLLNAGDHIVASSSLYGGTINLLAHTLP 125
Query: 473 RLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVV 652
R GI TTF +++ ++A++ NTK++ ET NP L+V+DI + IA I +++
Sbjct: 126 RFGITTTFVKPRDLDAFRSAIKPNTKLVIGETIGNPGLEVLDIPKVAAIAH-EAKIPLLI 184
Query: 653 DNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAI 772
DNTF TPYL RP+ GADIVM+S TK++ GH I GA I
Sbjct: 185 DNTFATPYLSRPIELGADIVMHSATKWIGGHGIAIGGAII 224
>UniRef50_Q49UL3 Cluster: Cystathionine beta-lyase cystathionine
gamma-synthase; n=14; Staphylococcus|Rep: Cystathionine
beta-lyase cystathionine gamma-synthase - Staphylococcus
saprophyticus subsp. saprophyticus (strain ATCC 15305
/DSM 20229)
Length = 367
Score = 155 bits (376), Expect = 1e-36
Identities = 77/204 (37%), Positives = 117/204 (57%)
Frame = +2
Query: 191 NSAAVVTPIVTSTTFKQPAPAEHTGFEYGRSGNPTRNTLEECLAALDGGKYGLTFASXXX 370
++ A+ PI ST ++ P E TG++Y R+ NPTR+ EE A L+ G +S
Sbjct: 15 HTGAIANPIYLSTAYQHPHLGESTGYDYTRTKNPTRSAFEEAFAKLEHGTASFATSSGMS 74
Query: 371 XXXXXXXXXNHGDHIVSSDDVYGGTNRLLRQVIARLGINTTFTDFTNIEKVKNAMQENTK 550
GD I+ S D+YGGT RL + GI+ + DF N E+V+ ++ E+TK
Sbjct: 75 AIQLICNLFKSGDEILVSFDLYGGTFRLFDFYEQQYGIHFKYVDFLNYEEVEQSITEHTK 134
Query: 551 MIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQRPLXFGADIVMYSLTK 730
++IE +NP + VD++ I + +++ ++DNTFLTPYL PL GADIV++S TK
Sbjct: 135 ALFIEPISNPQMIEVDVDPFY-ILSKKFNLLTIIDNTFLTPYLSTPLEDGADIVLHSATK 193
Query: 731 YMNGHSDVIMGAAIVNDKAIGXKL 802
Y+ GH+DV+ G V D + +L
Sbjct: 194 YIGGHNDVLAGVVTVKDNQLAEQL 217
>UniRef50_A1HQW4 Cluster: Cystathionine gamma-synthase; n=1;
Thermosinus carboxydivorans Nor1|Rep: Cystathionine
gamma-synthase - Thermosinus carboxydivorans Nor1
Length = 392
Score = 153 bits (371), Expect = 5e-36
Identities = 83/222 (37%), Positives = 124/222 (55%), Gaps = 8/222 (3%)
Frame = +2
Query: 149 ATIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPAPAEHT--------GFEYGRSGNPTRNT 304
+T+A+HAG + V PIV S+ + + A+ GF Y R NPT
Sbjct: 7 STLAVHAGTASPASATEPKVLPIVASSVWSFDSLAQLDDVYENKVPGFVYSRISNPTVEL 66
Query: 305 LEECLAALDGGKYGLTFASXXXXXXXXXXXXNHGDHIVSSDDVYGGTNRLLRQVIARLGI 484
LE+ + L+GG + GDHIV+ +YGGT LL+ +A+LG+
Sbjct: 67 LEQAVGMLEGGAAAAYASGMAAIATAIFAEVRQGDHIVAHHVLYGGTYALLKNEMAKLGV 126
Query: 485 NTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTF 664
TF D ++ V A++ NTK++++ET NPL++V+DI AIV++AR+ V VDNTF
Sbjct: 127 EVTFVDCNDLSAVAQAIRPNTKILYLETICNPLMEVLDIPAIVQLART-VKAKVYVDNTF 185
Query: 665 LTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVNDKAI 790
+PY +PL GAD+V++S TKY+NGHSD + G + + I
Sbjct: 186 ASPYHCQPLAHGADVVLHSATKYLNGHSDAMAGVIVADSDFI 227
>UniRef50_P00935 Cluster: Cystathionine gamma-synthase (EC 2.5.1.48)
(CGS) (O-succinylhomoserine (thiol)-lyase); n=123;
Proteobacteria|Rep: Cystathionine gamma-synthase (EC
2.5.1.48) (CGS) (O-succinylhomoserine (thiol)-lyase) -
Escherichia coli (strain K12)
Length = 386
Score = 153 bits (371), Expect = 5e-36
Identities = 85/219 (38%), Positives = 121/219 (55%), Gaps = 1/219 (0%)
Frame = +2
Query: 149 ATIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPAPAEHTGFEYGRSGNPTRNTLEECLAAL 328
ATIA+ +G ++ VV PI S+T+ E +Y R GNPTR+ ++ LA L
Sbjct: 6 ATIAVRSGLNDDE-QYGCVVPPIHLSSTYNFTGFNEPRAHDYSRRGNPTRDVVQRALAEL 64
Query: 329 DGGKYG-LTFASXXXXXXXXXXXXNHGDHIVSSDDVYGGTNRLLRQVIARLGINTTFTDF 505
+GG LT GD +V+ D YGG+ RL + R F D
Sbjct: 65 EGGAGAVLTNTGMSAIHLVTTVFLKPGDLLVAPHDCYGGSYRLFDSLAKRGCYRVLFVDQ 124
Query: 506 TNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQR 685
+ + ++ A+ E K++ +E+P+NPLL+VVDI I +AR G + VVDNTFL+P LQ
Sbjct: 125 GDEQALRAALAEKPKLVLVESPSNPLLRVVDIAKICHLAREVG-AVSVVDNTFLSPALQN 183
Query: 686 PLXFGADIVMYSLTKYMNGHSDVIMGAAIVNDKAIGXKL 802
PL GAD+V++S TKY+NGHSDV+ G I D + +L
Sbjct: 184 PLALGADLVLHSCTKYLNGHSDVVAGVVIAKDPDVVTEL 222
>UniRef50_P44502 Cluster: Cystathionine gamma-synthase (EC 2.5.1.48)
(CGS) (O-succinylhomoserine (thiol)-lyase); n=14;
Bacteria|Rep: Cystathionine gamma-synthase (EC 2.5.1.48)
(CGS) (O-succinylhomoserine (thiol)-lyase) - Haemophilus
influenzae
Length = 369
Score = 152 bits (368), Expect = 1e-35
Identities = 80/222 (36%), Positives = 123/222 (55%), Gaps = 1/222 (0%)
Frame = +2
Query: 128 LKQKPGFATIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPAPAEHTGFEYGRSGNPTRNTL 307
+ Q+ T+ AG ++ + AV PI ST + E TGF+Y R+ NPTR L
Sbjct: 1 MTQQYAIDTLLAQAGNRSDE-RTGAVSAPIFLSTAYGHCGIGESTGFDYTRTKNPTRTVL 59
Query: 308 EECLAALDGGKYGLTFASXXXXXXXXXXXXNHGDHIVSSDDVYGGTNRLLR-QVIARLGI 484
EE +A L+ G G F+S D + S DVYGGT RLL +
Sbjct: 60 EETIAKLENGDRGFAFSSGMAAIQVLMTLFTAPDEWIVSSDVYGGTYRLLDFSYKNNNSV 119
Query: 485 NTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTF 664
+ + + ++ A+ NTK I+IETP+NPL++ D+ I K+A+ + +++++VDNTF
Sbjct: 120 KPVYVNTASASAIEAAINPNTKAIFIETPSNPLMEECDVVEIAKLAK-KHNLMLIVDNTF 178
Query: 665 LTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVNDKAI 790
LTP L RPL GAD+V++S TKY+ GH+D ++G + + +
Sbjct: 179 LTPVLSRPLDLGADVVIHSGTKYIAGHNDALVGLIVAKGQEL 220
>UniRef50_Q1IQ68 Cluster: Cystathionine gamma-synthase; n=1;
Acidobacteria bacterium Ellin345|Rep: Cystathionine
gamma-synthase - Acidobacteria bacterium (strain
Ellin345)
Length = 400
Score = 151 bits (366), Expect = 2e-35
Identities = 77/215 (35%), Positives = 125/215 (58%), Gaps = 1/215 (0%)
Frame = +2
Query: 149 ATIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPAPAEHTGFEYGRSGNPTRNTLEECLAAL 328
+T+AI G+ + ++++++ P+ ++TF A GF Y R NPT + LE+ + L
Sbjct: 9 STLAIRGGRSLDS-HASSILFPLYQTSTFVHDAVGVDKGFSYSRVSNPTVDALEKAIGVL 67
Query: 329 DGGKYGLTFASXXXXXXXXXXXX-NHGDHIVSSDDVYGGTNRLLRQVIARLGINTTFTDF 505
+G + F + GDH V S+ +YGGT RL R+++ LGI +F D
Sbjct: 68 EGTPPAVCFRTGMAAVTTLFLSVLRAGDHAVLSEVIYGGTMRLFREILDHLGITASFVDT 127
Query: 506 TNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQR 685
++ V+ A++ TK+I+IETP NP LK+ DI A+ ++A+ R I++ VDNTFLT LQ
Sbjct: 128 SDAANVERAIRPETKIIFIETPGNPTLKLTDIAAVAEVAK-RHSILLAVDNTFLTSLLQN 186
Query: 686 PLXFGADIVMYSLTKYMNGHSDVIMGAAIVNDKAI 790
GADI + S TKY++GH+ + G+ +D+ +
Sbjct: 187 VFELGADISLLSTTKYIDGHNATLGGSLATHDEKL 221
>UniRef50_Q97PS4 Cluster: Transulfuration enzyme family protein;
n=25; Lactobacillales|Rep: Transulfuration enzyme family
protein - Streptococcus pneumoniae
Length = 364
Score = 149 bits (361), Expect = 8e-35
Identities = 81/217 (37%), Positives = 126/217 (58%)
Frame = +2
Query: 152 TIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPAPAEHTGFEYGRSGNPTRNTLEECLAALD 331
TI AG + ++ + A+VTP+ STT++ P TGF+Y R+ NPTR+ EE LAA++
Sbjct: 9 TILAQAGIKSDE-ATGALVTPLHFSTTYQHPEFGRSTGFDYTRTKNPTRSKAEEVLAAIE 67
Query: 332 GGKYGLTFASXXXXXXXXXXXXNHGDHIVSSDDVYGGTNRLLRQVIARLGINTTFTDFTN 511
Y L +S G +++ D+YGG+ R QV + T+ +
Sbjct: 68 SADYALATSSGMSAIVLAFSVFPVGSKVLAVRDLYGGSFRWFNQVEQEGHFHFTYAN--T 125
Query: 512 IEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQRPL 691
E++ ++++ +++IETPTNPL+ DIE + K+A ++G VVVDNTF +P QRP+
Sbjct: 126 EEELIAELEKDVDVLYIETPTNPLMLEFDIEKLAKLAHAKG-AKVVVDNTFYSPIYQRPI 184
Query: 692 XFGADIVMYSLTKYMNGHSDVIMGAAIVNDKAIGXKL 802
GADIV++S TKY+ GH+DV+ G + N + KL
Sbjct: 185 EDGADIVLHSATKYLAGHNDVLAGVVVTNSLELYEKL 221
>UniRef50_Q0ALD7 Cluster: Cystathionine gamma-synthase; n=2;
Hyphomonadaceae|Rep: Cystathionine gamma-synthase -
Maricaulis maris (strain MCS10)
Length = 382
Score = 148 bits (358), Expect = 2e-34
Identities = 80/212 (37%), Positives = 121/212 (57%), Gaps = 2/212 (0%)
Frame = +2
Query: 152 TIAIHAGQEPEK-WNSAAVVTPIVTSTTFKQPAPAEHTGFEYGRSGNPTRNTLEECLAAL 328
T AI AG ++ WN AV+ P+ ST +++ PA F+Y R+GNP R+ L + +A L
Sbjct: 7 TKAIRAGLNTDRSWN--AVIPPLSLSTAYRREDPAIQPAFDYARTGNPGRSLLADAIAEL 64
Query: 329 DGGKYGLTFASXXXXXXXXXXXXNHGDHIVSSDDVYGGTNRLLRQVIARLG-INTTFTDF 505
+ + S HG ++ S D YGGT RLL R G + + D
Sbjct: 65 ENAAGAIVTGSGMSAIDLLLHDIPHGARVICSHDAYGGTRRLL-DARGRGGRLIPVYVDT 123
Query: 506 TNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQR 685
T++EKV +A+ E+ +I ETP+NP L++ DI+ + ++AR+ G + VDNT ++P LQR
Sbjct: 124 TDLEKVADALNEDAALIIAETPSNPRLRISDIKGLARLARNAGTEL-AVDNTVMSPVLQR 182
Query: 686 PLXFGADIVMYSLTKYMNGHSDVIMGAAIVND 781
PL +GAD + S+TK +NGHSD++ G D
Sbjct: 183 PLDWGADYSVQSVTKLLNGHSDMVGGVVCCAD 214
>UniRef50_Q8G805 Cluster: Cystathionine beta-lyase; n=2;
Bifidobacterium longum|Rep: Cystathionine beta-lyase -
Bifidobacterium longum
Length = 412
Score = 147 bits (357), Expect = 2e-34
Identities = 81/211 (38%), Positives = 118/211 (55%), Gaps = 7/211 (3%)
Frame = +2
Query: 191 NSAAVVTPIVTSTTFKQPAPAEHTGFEYGRSGNPTRNTLEECLAALDGGKYGLTFASXXX 370
N+ AV PI STT+ ++Y RSGNPTR+ LE+ +A L+ G G FAS
Sbjct: 18 NTGAVNPPIYNSTTYAFEKVDAMPRYDYARSGNPTRDFLEQQIAQLEQGTRGFAFASGLA 77
Query: 371 XXXXXXXXXNHGDHIVSSDDVYGGTNRLLRQVIARLGINTTFTDFTNIEKVKNAMQEN-- 544
GD IV D++YGG+ L + R GI D +I ++ A++ +
Sbjct: 78 AIHAVLSIFKPGDRIVVGDNIYGGSYSQLNEFFTRWGILVEAVDTQDIAALEAAVKGDRA 137
Query: 545 -----TKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQRPLXFGADI 709
+ ++ ET TNPLLKV D+ AI +A G + +VDNTF+TPYLQ+PL GAD+
Sbjct: 138 NGIVPAQAVYFETLTNPLLKVNDVRAISTVAHRFG-ALSIVDNTFVTPYLQKPLALGADV 196
Query: 710 VMYSLTKYMNGHSDVIMGAAIVNDKAIGXKL 802
V++S TKY+ GHSDV G +V+ + + ++
Sbjct: 197 VIHSATKYLAGHSDVNAGLVVVSGEDLASRV 227
>UniRef50_A4EYE9 Cluster: Cystathionine beta-lyase/cystathionine
gamma-synthase; n=2; Roseobacter|Rep: Cystathionine
beta-lyase/cystathionine gamma-synthase - Roseobacter
sp. SK209-2-6
Length = 453
Score = 147 bits (357), Expect = 2e-34
Identities = 81/216 (37%), Positives = 128/216 (59%), Gaps = 9/216 (4%)
Frame = +2
Query: 143 GFATIAIHAGQEPEKWNSAAVVTPIVTSTTF----KQPAPAE----HTGFEYGRSGNPTR 298
G +T A+HAG + + AV TPI ++TF Q E F Y R GNP++
Sbjct: 49 GLSTCAVHAGTHDDP-RTGAVGTPIYQTSTFVLNDDQYESVEGGFARDRFIYSRYGNPSQ 107
Query: 299 NTLEECLAALDGGKYGLTFASXXXXXXXXXXXX-NHGDHIVSSDDVYGGTNRLLRQVIAR 475
++E LAAL+G + + F+S + G H+V++ D+YGGT L Q
Sbjct: 108 WAVQEKLAALEGAESAIVFSSGMAAITAGVLAMVDKGAHVVAASDLYGGTYNLFNQEFPS 167
Query: 476 LGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVD 655
G++ T D +++ ++ A+Q NT+ ++ E TNP+LKVV+I A+V+IA+ R ++ ++VD
Sbjct: 168 FGMSATLVDSYDLDAIEEAIQPNTQALYFEAITNPVLKVVNIPALVEIAK-RHNLRLIVD 226
Query: 656 NTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMG 763
+TF P + RPL G D+V++S +KY+NGHSD+I G
Sbjct: 227 STFAPPPVMRPLELGVDLVIHSASKYLNGHSDLIAG 262
>UniRef50_Q5QU17 Cluster: Methionine gamma-lyase; n=29; cellular
organisms|Rep: Methionine gamma-lyase - Idiomarina
loihiensis
Length = 408
Score = 147 bits (356), Expect = 3e-34
Identities = 83/223 (37%), Positives = 124/223 (55%), Gaps = 9/223 (4%)
Frame = +2
Query: 149 ATIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPAPAEHT--------GFEYGRSGNPTRNT 304
AT IHAG + + A + P+ ++TF+ + + T G+ Y R GNPT
Sbjct: 15 ATQVIHAGAAHDDPHGA-LTAPLYQTSTFRFSSAEQGTRRFAGEEEGYIYSRLGNPTTAE 73
Query: 305 LEECLAALDGGKYGLTFASXXXXXXXXXXXX-NHGDHIVSSDDVYGGTNRLLRQVIARLG 481
LE +A+L+G + A+ GDHIV SD +YG + L ++ R G
Sbjct: 74 LERRMASLEGYEAAAAAATGMGAIAAATMAFVRSGDHIVVSDAIYGCSFALFSELFERFG 133
Query: 482 INTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNT 661
+ F D N +K ++ENT+++++ETP NP LKVVDIE + + + DI +VVDNT
Sbjct: 134 VEADFIDLNNEGLLKETLRENTRLVFLETPANPHLKVVDIEKVHAVI-ADSDIRLVVDNT 192
Query: 662 FLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVNDKAI 790
F+TP +Q+P GADIV++S TK++NGH DV+ G +D I
Sbjct: 193 FMTPLMQQPKRHGADIVVHSATKFLNGHGDVVAGIICGSDDDI 235
>UniRef50_Q65SV6 Cluster: Putative uncharacterized protein; n=1;
Mannheimia succiniciproducens MBEL55E|Rep: Putative
uncharacterized protein - Mannheimia succiniciproducens
(strain MBEL55E)
Length = 332
Score = 146 bits (354), Expect = 6e-34
Identities = 82/221 (37%), Positives = 126/221 (57%), Gaps = 10/221 (4%)
Frame = +2
Query: 146 FATIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPAPA--------EHTGFEYGRSGNPTRN 301
F T +HAG P+ N V PIV STT+ + + GF Y R NPT N
Sbjct: 34 FETQCLHAGYSPK--NGEPRVQPIVQSTTYTYDSAESIGKLFDLQEAGFFYTRLANPTTN 91
Query: 302 TLEECLAALDGGKYGLTFASXXXXXXXXXXXX-NHGDHIVSSDDVYGGTNRLLRQVIARL 478
EE LAAL+GG L AS GDH +S+ ++YGGT L ++
Sbjct: 92 AAEEKLAALEGGVAALCTASGQAATFYALMNLVESGDHFISTTNIYGGTYNLFAHTFRKM 151
Query: 479 GINTTFTDFT-NIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVD 655
G+ TF + N+++++ A++ NTK ++ ET +NP L+V+DIE +A++ + +++D
Sbjct: 152 GVEVTFVNQDDNLDELRKAIRPNTKAVFGETISNPTLRVLDIEKFAALAQA-ANAPLIID 210
Query: 656 NTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVN 778
NTF TPY RP +GA+IV++S +KY++GH+ V +G AI++
Sbjct: 211 NTFATPYFCRPFKYGANIVVHSTSKYLDGHA-VALGGAIID 250
>UniRef50_A1ID11 Cluster: Cystathionine gamma-synthase; n=1;
Candidatus Desulfococcus oleovorans Hxd3|Rep:
Cystathionine gamma-synthase - Candidatus Desulfococcus
oleovorans Hxd3
Length = 392
Score = 146 bits (354), Expect = 6e-34
Identities = 80/226 (35%), Positives = 129/226 (57%), Gaps = 10/226 (4%)
Frame = +2
Query: 143 GFATIAIHAGQEPEKWNS-AAVVTPIVTSTTF--------KQPAPAEHTGFEYGRSGNPT 295
G +T A+HAG+ ++N +V TPIV ++TF K+ A FEYGR G+PT
Sbjct: 8 GISTKAVHAGEI--RYNEYGSVTTPIVQTSTFIFKNIDEIKKLAVGAVERFEYGRYGHPT 65
Query: 296 RNTLEECLAALDGGKYGLTFASXXXXXXXXXXXX-NHGDHIVSSDDVYGGTNRLLRQVIA 472
+ E LA L+G + + F+S GDHI+ +DD Y T + +
Sbjct: 66 QIAAEHKLAFLEGAEDAVLFSSGMSAITTTLFGLLKSGDHIIITDDAYRRTLEFCKACLV 125
Query: 473 RLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVV 652
+ I T + E ++ A++ NT++ + E+PTNP L ++D+E ++ I + +G I+VV
Sbjct: 126 KFDIECTVVKMCDYEAMEKAIKPNTRLFFSESPTNPYLNIMDLERLIGIFKDKG-ILVVS 184
Query: 653 DNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVNDKAI 790
D+TF TPY Q+PL +G DIV++S TKY+ GH+D++ G + + K +
Sbjct: 185 DSTFATPYNQKPLEYGVDIVIHSATKYLAGHNDLLSGVVLGSKKLV 230
>UniRef50_A1ZDN6 Cluster: Cystathionine beta-lyase; n=1; Microscilla
marina ATCC 23134|Rep: Cystathionine beta-lyase -
Microscilla marina ATCC 23134
Length = 380
Score = 146 bits (353), Expect = 7e-34
Identities = 79/208 (37%), Positives = 120/208 (57%), Gaps = 1/208 (0%)
Frame = +2
Query: 152 TIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPAPAEHTGFEYGRSGNPTRNTLEECLAALD 331
T+ +H G ++ + +PI TS++F+ T Y + P + ++ + LAAL+
Sbjct: 9 TLCVHTGTYHDQ-AQPGINSPIYTSSSFEYLDTDARTYPRYFNT--PNQESVVKKLAALE 65
Query: 332 GGKYGLTFASXXXXXXXXXXXX-NHGDHIVSSDDVYGGTNRLLRQVIARLGINTTFTDFT 508
G+ G+ F S DH++ D+YGGT R + R GI +F D T
Sbjct: 66 SGEDGIIFGSGMAAISTTLLALLKKEDHVLFQADLYGGTQRFITTDFPRFGIEYSFGDAT 125
Query: 509 NIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQRP 688
NIE + A+Q NTK+I+IETP+NPLL++ DIE IV +A+ G ++ ++DNTF +P Q P
Sbjct: 126 NIEMFEEAIQFNTKLIYIETPSNPLLRLTDIEKIVALAKQYG-VLTMIDNTFASPINQNP 184
Query: 689 LXFGADIVMYSLTKYMNGHSDVIMGAAI 772
+ G D+VM+S TKY+ GHSD+ GA I
Sbjct: 185 IPMGIDLVMHSGTKYLGGHSDLSCGAII 212
>UniRef50_A3VS82 Cluster: Cystathionine gamma-synthase; n=1;
Parvularcula bermudensis HTCC2503|Rep: Cystathionine
gamma-synthase - Parvularcula bermudensis HTCC2503
Length = 392
Score = 145 bits (352), Expect = 1e-33
Identities = 81/224 (36%), Positives = 118/224 (52%)
Frame = +2
Query: 131 KQKPGFATIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPAPAEHTGFEYGRSGNPTRNTLE 310
K P T+ AG E A+ P+ S+T+ P + ++YGRS PTR+ LE
Sbjct: 9 KPAPHAETVLAQAGVG-EDCGHGAIAPPLYLSSTYLWDDPDKKPAYDYGRSRTPTRSVLE 67
Query: 311 ECLAALDGGKYGLTFASXXXXXXXXXXXXNHGDHIVSSDDVYGGTNRLLRQVIARLGINT 490
LA L+GG L A+ G IV+ D YGGT RLL +
Sbjct: 68 TLLAELEGGGGALVCATGMAAIGLPLDRLPAGAKIVAPHDCYGGTYRLLAAHADKGRFEV 127
Query: 491 TFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLT 670
F D T E ++ A +I++ETP+NPL+++ D+ +A+ G + + DNTFL+
Sbjct: 128 RFLDQTTEEALRAARDFAPDLIYLETPSNPLMRITDLSRWTALAKEIG-ALTLADNTFLS 186
Query: 671 PYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVNDKAIGXKL 802
P LQRPL +G D+V++S TKY+NGH+D+I GA I D + +L
Sbjct: 187 PILQRPLEWGCDMVVHSTTKYINGHTDIIGGALITKDPELASEL 230
>UniRef50_Q181I0 Cluster: Methionine gamma-lyase; n=2; Clostridium
difficile|Rep: Methionine gamma-lyase - Clostridium
difficile (strain 630)
Length = 384
Score = 145 bits (351), Expect = 1e-33
Identities = 81/221 (36%), Positives = 121/221 (54%), Gaps = 8/221 (3%)
Frame = +2
Query: 152 TIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPAPAEHT-------GFEYGRSGNPTRNTLE 310
T IH G + + A+ TPI + TF EH G+ Y R NPT LE
Sbjct: 11 TKIIHWGHSADP-TTGALATPICQTATFAAKT-VEHFEELCMTWGYVYTRECNPTLTELE 68
Query: 311 ECLAALDGGKYGLTFASXXXXXXXXXXXX-NHGDHIVSSDDVYGGTNRLLRQVIARLGIN 487
LA L+ + ++ S GDHIVSSD ++ T + +++++ G+
Sbjct: 69 AKLAMLENAESAISSTSGMGAITSTILALVKSGDHIVSSDGIFSHTKLFMSELLSKFGVE 128
Query: 488 TTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFL 667
TF D N + VK AM+ NTK+++IE+P NP L +VDI+ I +IA + +VD+TF
Sbjct: 129 VTFVDAVNPQNVKEAMRPNTKIVYIESPLNPSLDLVDIKTIAEIAHENKS-LAIVDSTFG 187
Query: 668 TPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVNDKAI 790
TP +QRP+ GAD+V++SLTK++NGH D +G A+ K +
Sbjct: 188 TPIVQRPIDLGADLVIHSLTKFINGHGDT-LGGAVAGSKEL 227
>UniRef50_O94350 Cluster: Cystathionine beta-lyase; n=27; cellular
organisms|Rep: Cystathionine beta-lyase -
Schizosaccharomyces pombe (Fission yeast)
Length = 390
Score = 145 bits (351), Expect = 1e-33
Identities = 81/209 (38%), Positives = 121/209 (57%), Gaps = 2/209 (0%)
Frame = +2
Query: 152 TIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPAPAEHTG-FEYGRSGNPTRNTLEECLAAL 328
T +H +++++++V PI S TFKQP EH G F+Y RSGNPTR+ L+ LA L
Sbjct: 11 TELVHVEGNEDQYHASSV--PIYQSATFKQPC-LEHMGKFDYTRSGNPTRSVLQVHLAKL 67
Query: 329 DGGKYGLTFASXXXXXXXXXXXXNHGDHIVSSDDVYGGTNRLLRQVIARLGINTTFTDFT 508
K+ ++ H+V+ D+YGG++RLL + G D +
Sbjct: 68 MKAKHAFVTSNGMSALDMILRCCKSNSHVVAGHDLYGGSDRLLSFNQRQYGFKVDNVDTS 127
Query: 509 NIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRG-DIIVVVDNTFLTPYLQR 685
++ + A++ +T ++ IE+PTNP + + DI AIVKI RS+ D ++V+DNT L+P L
Sbjct: 128 DLAAFEAALRPDTNLVLIESPTNPRISICDIRAIVKITRSKAKDALLVMDNTMLSPVLCN 187
Query: 686 PLXFGADIVMYSLTKYMNGHSDVIMGAAI 772
PL FG DIV S TKY++GH D +MG I
Sbjct: 188 PLDFGYDIVYESATKYLSGHHD-LMGGVI 215
>UniRef50_Q8RI67 Cluster: Cystathionine beta-lyase; n=2;
Bacteria|Rep: Cystathionine beta-lyase - Fusobacterium
nucleatum subsp. nucleatum
Length = 419
Score = 144 bits (350), Expect = 2e-33
Identities = 72/173 (41%), Positives = 107/173 (61%), Gaps = 1/173 (0%)
Frame = +2
Query: 254 EHTGFEYGRSGNPTRNTLEECLAALDGGKYGLTFASXXXXXXXXXXXXNH-GDHIVSSDD 430
+ GF Y R+ NP R L E + ++GG+ + +S GDHI+S
Sbjct: 72 DEKGFCYNRNRNPNRTALIELMNYVEGGEDSIGCSSGMAAISSSIIAHTKTGDHILSDKT 131
Query: 431 VYGGTNRLLRQVIARLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAI 610
+YG T + +++ + G+ TTF DFTNIE+VK ++ NT +++ ET +NPL+ V +++ +
Sbjct: 132 LYGETLEIFTKILQKYGVETTFVDFTNIEEVKKNIKSNTVILYTETVSNPLIGVPNLKVL 191
Query: 611 VKIARSRGDIIVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAA 769
IA S + I +VDNTF+T L +PL FGADIV+ SLTK+ NGHSDV+ GAA
Sbjct: 192 ANIAHS-NNAIFIVDNTFMTGALVQPLKFGADIVVNSLTKFANGHSDVVCGAA 243
>UniRef50_Q4QFT8 Cluster: Cystathionine beta-lyase-like protein;
n=4; Eukaryota|Rep: Cystathionine beta-lyase-like
protein - Leishmania major
Length = 459
Score = 143 bits (346), Expect = 5e-33
Identities = 71/193 (36%), Positives = 110/193 (56%), Gaps = 2/193 (1%)
Frame = +2
Query: 212 PIVTSTTFKQPAPAEHTGFEYGRSGNPTRNTLEECLAALDGGKYGLTFASXXXXXXXXXX 391
PI + TF QP E ++Y RSGNPTR +E +A L+G F+S
Sbjct: 84 PIYQTATFVQPDIEEFGPYDYSRSGNPTRTAIETLVANLEGAHAAFAFSSGMAALQTLVT 143
Query: 392 XXNHGDHIVSSDDVYGGTNRLLRQVIARLGINTTFTDFTNIEKVKNAMQEN--TKMIWIE 565
N GD I++S D+YGG +RLL Q+ + LG+ F + E V+ A+ +N K++ +E
Sbjct: 144 TLNAGDTILASSDLYGGMHRLLTQITSCLGMTVVFVPMWDTEAVRQALVDNPAAKLLHME 203
Query: 566 TPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGH 745
+PTNPL+++VDI A+ + A + ++ V +DNT ++P PL G D ++S TK++ GH
Sbjct: 204 SPTNPLMRIVDIRAVCEAAHAH-NVKVSIDNTMMSPLRCTPLALGCDYSIHSATKFLCGH 262
Query: 746 SDVIMGAAIVNDK 784
SD + G V +
Sbjct: 263 SDTMCGLICVKSE 275
>UniRef50_Q5WAZ1 Cluster: Methionine gamma-lyase; n=1; Bacillus
clausii KSM-K16|Rep: Methionine gamma-lyase - Bacillus
clausii (strain KSM-K16)
Length = 402
Score = 142 bits (343), Expect = 1e-32
Identities = 80/221 (36%), Positives = 115/221 (52%), Gaps = 10/221 (4%)
Frame = +2
Query: 131 KQKPGFATIAIHAGQEPEKWNSAAVVTP-IVTSTTFKQPAPAE--------HTGFEYGRS 283
K + GF T H G + WN + ++P I ST F+ P +E YGR
Sbjct: 12 KNRLGFQTACTHGG---DHWNKSGHLSPPICQSTAFEFPTTSEGAVRAADIKADEFYGRW 68
Query: 284 GNPTRNTLEECLAALDGGKYGLTFASXXXXXXXXXXXX-NHGDHIVSSDDVYGGTNRLLR 460
G+ LE +AAL+ L +S N GDH ++ + Y T L
Sbjct: 69 GSRNERELEALIAALEEADDALCASSGLGAISMITHAFLNPGDHFIAVHNCYSETKILHE 128
Query: 461 QVIARLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDI 640
+ +L ++ TF D ++I K A+Q NTK+++ ETP NP L +VDI + + + D
Sbjct: 129 SLAEQLSVDVTFIDSSDIHHYKQAIQPNTKLVFAETPANPTLSLVDISKVATLVHEQSDA 188
Query: 641 IVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMG 763
+ VVD+TF TPY Q+PL GADIV++S TKY+ GHSDV+ G
Sbjct: 189 VFVVDSTFATPYNQKPLKHGADIVVHSATKYLGGHSDVVAG 229
>UniRef50_Q8R9M2 Cluster: Cystathionine beta-lyases/cystathionine
gamma-synthases; n=5; Clostridia|Rep: Cystathionine
beta-lyases/cystathionine gamma-synthases -
Thermoanaerobacter tengcongensis
Length = 394
Score = 140 bits (340), Expect = 3e-32
Identities = 81/229 (35%), Positives = 125/229 (54%), Gaps = 9/229 (3%)
Frame = +2
Query: 128 LKQKPGFATIAIHAGQEPEKWNSAAVVTPIVTSTTF--------KQPAPAEHTGFEYGRS 283
+K++ F T AIH G+E +K A+ PI +TTF ++ E + Y R
Sbjct: 1 MKKEFRFDTKAIH-GEELKKNPENALNPPIFQTTTFVFEDLDHVEKVMSFESQDYVYTRG 59
Query: 284 GNPTRNTLEECLAALDGGKYGLTFASXXXXXXXXXXXX-NHGDHIVSSDDVYGGTNRLLR 460
NPT E +A L+ GK + F+S D +++ +YG + ++
Sbjct: 60 NNPTLRLFENRMAELEYGKGAVAFSSGMAAISSVLFSLLRPNDKVLAHKTLYGSSYNVIT 119
Query: 461 QVIARLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDI 640
++ + G+ D T++E++K ++ + K+I+ ETP+NP L ++DIE + KIA RG I
Sbjct: 120 NLLPKYGVKYKLIDMTSLEELKESLDDTVKVIYFETPSNPDLSIIDIEEVSKIAYQRG-I 178
Query: 641 IVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVNDKA 787
VVVDNTF TP Q PL GAD+V++S TKY+ GH D + G AI D+A
Sbjct: 179 KVVVDNTFATPCFQNPLLLGADVVVHSATKYICGHGDALGGVAISKDEA 227
>UniRef50_A0JSU6 Cluster: Cys/Met metabolism
pyridoxal-phosphate-dependent enzymes; n=7;
Actinomycetales|Rep: Cys/Met metabolism
pyridoxal-phosphate-dependent enzymes - Arthrobacter sp.
(strain FB24)
Length = 394
Score = 140 bits (340), Expect = 3e-32
Identities = 81/222 (36%), Positives = 117/222 (52%), Gaps = 5/222 (2%)
Frame = +2
Query: 152 TIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPAPAEHTGFEYGRSGNPTRNTLEECLAALD 331
T+ + AG+ P K A V PIV S+T+ P YGR NPT + LEE L L+
Sbjct: 15 TVVVAAGRPPRK-RDAPVNPPIVLSSTYFGTGPLADGDRGYGRYSNPTWDPLEEALGQLE 73
Query: 332 GGKY-GLTFASXXXXXXXXXXXXNHGDHIVSSDDVYGGTNRLLRQVIARLGINTTFTDFT 508
G GL +AS G +V Y G+ + ++ + D
Sbjct: 74 GASLPGLLYASGLAAVSSALSLIPAGGVLVMPSHSYAGSLVMATELAEKGLFELRTVDIA 133
Query: 509 NIEKVK----NAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPY 676
+ + VK A + M+W+E+PTNP+L + DI A+ A + G IVV DNTF TP
Sbjct: 134 DTDAVKALLAPAEGKPASMLWLESPTNPMLGIADIRALTAAAHAAG-AIVVTDNTFSTPL 192
Query: 677 LQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVNDKAIGXKL 802
+Q+PL G+D+V++S+TKY+ GHSDV++GA + +D AI KL
Sbjct: 193 VQQPLSLGSDVVLHSVTKYLAGHSDVVLGALVTSDAAIRAKL 234
>UniRef50_O15564 Cluster: Methionine gamma-lyase; n=2; Trichomonas
vaginalis|Rep: Methionine gamma-lyase - Trichomonas
vaginalis
Length = 396
Score = 140 bits (340), Expect = 3e-32
Identities = 75/214 (35%), Positives = 119/214 (55%), Gaps = 9/214 (4%)
Frame = +2
Query: 149 ATIAIHAGQEPEKWNSAAVVTPIVTSTTF-----KQPA---PAEHTGFEYGRSGNPTRNT 304
AT IHA P+K A + PI ++TF +Q + +G+ Y R GNPT +
Sbjct: 9 ATACIHAN--PQKDQFGAAIPPIYQTSTFVFDNCQQGGNRFAGQESGYIYTRLGNPTVSN 66
Query: 305 LEECLAALDGGKYGL-TFASXXXXXXXXXXXXNHGDHIVSSDDVYGGTNRLLRQVIARLG 481
LE +A L+ + + T + GDH++S + +YG T+ L + + G
Sbjct: 67 LEGKIAFLEKTEACVATSSGMGAIAATVLTILKAGDHLISDECLYGCTHALFEHALTKFG 126
Query: 482 INTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNT 661
I F + +VK M+ NTK+++ ETP NP LK++D+E + K A S+ ++V+ DNT
Sbjct: 127 IQVDFINTAIPGEVKKHMKPNTKIVYFETPANPTLKIIDMERVCKDAHSQEGVLVIADNT 186
Query: 662 FLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMG 763
F +P + P+ FG D+V++S TKY+NGH+DV+ G
Sbjct: 187 FCSPMITNPVDFGVDVVVHSATKYINGHTDVVAG 220
>UniRef50_Q9KFD9 Cluster: Cystathionine gamma-synthase; n=3;
Bacillus|Rep: Cystathionine gamma-synthase - Bacillus
halodurans
Length = 381
Score = 140 bits (339), Expect = 4e-32
Identities = 67/168 (39%), Positives = 105/168 (62%), Gaps = 1/168 (0%)
Frame = +2
Query: 272 YGRSGNPTRNTLEECLAALDGGKYGL-TFASXXXXXXXXXXXXNHGDHIVSSDDVYGGTN 448
Y R GNP + L + +A+L+ + G+ T A GDH+++++D+YGGT
Sbjct: 54 YTRYGNPNSDDLGKGVASLEQAEDGVATSAGMSAILVALLALLEKGDHLIAANDLYGGTY 113
Query: 449 RLLRQVIARLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARS 628
+LL + + +LGI+ +F F E VK A+++ TK+++ ET TNPLL+V DI +V++ +
Sbjct: 114 QLLAEELPKLGIDVSFVPFQEREVVKRAIRKETKVLYSETVTNPLLRVEDIHQVVELGKE 173
Query: 629 RGDIIVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAI 772
G + V+DNTF TPY +PL G D+V++S TKY+ GHSDV G +
Sbjct: 174 HG-LSTVIDNTFATPYFVQPLTCGVDVVVHSATKYIGGHSDVTAGVVV 220
>UniRef50_A5WG79 Cluster: O-succinylhomoserine sulfhydrylase; n=6;
Proteobacteria|Rep: O-succinylhomoserine sulfhydrylase -
Psychrobacter sp. PRwf-1
Length = 434
Score = 140 bits (339), Expect = 4e-32
Identities = 79/228 (34%), Positives = 130/228 (57%), Gaps = 9/228 (3%)
Frame = +2
Query: 128 LKQKPGFATIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPAPAE--------HTGFEYGRS 283
L Q G TIA+ AGQ + + PI T++++ + A+ +G Y R
Sbjct: 35 LSQDYGMQTIAVRAGQH--RTDEGEHNEPIFTTSSYVYESAADAAAHFNGSKSGNVYSRH 92
Query: 284 GNPTRNTLEECLAALDGGKYGLTFASXXXXXXXX-XXXXNHGDHIVSSDDVYGGTNRLLR 460
NPT T E LAAL+GG+ + AS GDHIV++ ++G T L
Sbjct: 93 TNPTVRTFERRLAALEGGERAVATASGMGAILTMCLAYLKQGDHIVAAKQLFGSTVGLFN 152
Query: 461 QVIARLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDI 640
+ + G++ T+ D + + +A++ NT++++ ETP+NPL ++ D++AI +IA ++G
Sbjct: 153 NFMGKFGVSVTYVDCFDNQAWADAIEPNTRLLFCETPSNPLGQIADLQAISEIAHAQG-A 211
Query: 641 IVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVNDK 784
+ VVDN F TP +Q+PL FGAD+V++S TKY++G V+ GA + +D+
Sbjct: 212 LFVVDNCFATPAIQKPLDFGADVVIHSATKYIDGQGRVLGGALVGSDE 259
>UniRef50_A0JSB0 Cluster: O-acetylhomoserine/O-acetylserine
sulfhydrylase; n=130; cellular organisms|Rep:
O-acetylhomoserine/O-acetylserine sulfhydrylase -
Arthrobacter sp. (strain FB24)
Length = 444
Score = 140 bits (338), Expect = 5e-32
Identities = 86/222 (38%), Positives = 119/222 (53%), Gaps = 9/222 (4%)
Frame = +2
Query: 134 QKPGFATIAIHAGQEPEKWNSAAVVTPI--VTSTTFKQPAPAEHT------GFEYGRSGN 289
+K GF T A+HAG P+ + A V PI TS FK A + G Y R GN
Sbjct: 4 RKFGFRTRALHAGGTPDAEHGARAV-PIYQTTSFVFKDTQDAANLFALQKYGNIYSRIGN 62
Query: 290 PTRNTLEECLAALDGGKYGLTFASXXXXXXXXXXXXNH-GDHIVSSDDVYGGTNRLLRQV 466
PT EE +A+L+GG + +S GDHIV++ +YGGT L
Sbjct: 63 PTVAAFEERIASLEGGIGAVATSSGMAAEFITFAALTQAGDHIVAASQLYGGTVTQLDVT 122
Query: 467 IARLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIV 646
+ R G++TTF T+ A++ENTK I++E NP +V D+E + K+AR G I +
Sbjct: 123 LRRFGVDTTFVPGTDPADYAAAVRENTKAIFVEVVANPSSEVQDLEGLAKVARDAG-IPL 181
Query: 647 VVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAI 772
VVD T TPYL RP+ GADIV++S TK++ GH + G +
Sbjct: 182 VVDATLSTPYLVRPIEHGADIVIHSATKFLGGHGTTLGGVIV 223
>UniRef50_A3U7R8 Cluster: O-acetylhomoserine sulfhydrylase; n=8;
Bacteria|Rep: O-acetylhomoserine sulfhydrylase -
Croceibacter atlanticus HTCC2559
Length = 438
Score = 139 bits (337), Expect = 6e-32
Identities = 87/216 (40%), Positives = 119/216 (55%), Gaps = 8/216 (3%)
Frame = +2
Query: 149 ATIAIHAGQEPE-KWNSAAVVTPIVTSTTFKQPAPAEHT------GFEYGRSGNPTRNTL 307
AT A+HAG + N+ AV +S FK A + GF Y R NPT + L
Sbjct: 7 ATKALHAGHDTATNGNTRAVPIYQSSSYVFKDADHAANLFNLSEEGFIYTRINNPTNDIL 66
Query: 308 EECLAALDGGKYGLTFASXXXXXXXXXXXX-NHGDHIVSSDDVYGGTNRLLRQVIARLGI 484
E+ LA ++GG ++ AS GDHIV+S+ +YGGT LL+ + R GI
Sbjct: 67 EKRLADIEGGIAAVSTASGTAAINTTLLTLLKAGDHIVASNSLYGGTYNLLKVTLPRFGI 126
Query: 485 NTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTF 664
TTF D N E K A +ENT+ +IE+ NP L V+DIEAI I + ++VDNT
Sbjct: 127 TTTFVDPQNPENFKKASKENTRAYFIESLGNPKLDVLDIEAI-SIEAKAYKVPLIVDNTV 185
Query: 665 LTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAI 772
TP L P+ +GA+IV++SLTKY+NG+ + G I
Sbjct: 186 ATPALLNPINYGANIVIHSLTKYINGNGTALGGVII 221
>UniRef50_Q3JCU1 Cluster: Cystathionine gamma-synthase; n=1;
Nitrosococcus oceani ATCC 19707|Rep: Cystathionine
gamma-synthase - Nitrosococcus oceani (strain ATCC 19707
/ NCIMB 11848)
Length = 398
Score = 139 bits (336), Expect = 9e-32
Identities = 84/232 (36%), Positives = 123/232 (53%), Gaps = 12/232 (5%)
Frame = +2
Query: 131 KQKPGFATIAIHAGQEPEKWNSAAVVTPIVTSTTF-----KQPA---PAEHTGFEYGRSG 286
+Q+ GF T IH E + P+ +T F Q A E G+ Y R G
Sbjct: 4 EQEQGFTTQVIHGHNEKLDPVHGSTTPPLYLNTAFLFENADQGARRFAREEEGYVYARMG 63
Query: 287 NPTRNTLEECLAALDGGKYGLTFASXXXXXXXXXXX-XNHGDHIVSSDDVYGGTNRLLRQ 463
NP+ LE+ LA L+ G+ FAS GDHI+S ++YGGT
Sbjct: 64 NPSVEMLEKRLALLENGEAAAAFASGMGAISSLLLHLAQPGDHIISVREIYGGTYAFFEG 123
Query: 464 VIARLGINTTFTD--FTNIEKVKNAMQ-ENTKMIWIETPTNPLLKVVDIEAIVKIARSRG 634
+ R+G + T+ + ++E +A +++++++ETP+NP L +VD+EA + A RG
Sbjct: 124 QLKRMGCSITYFNPAAPDLEAELDAQYTSHSRVLYLETPSNPSLALVDLEACSRWAHKRG 183
Query: 635 DIIVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVNDKAI 790
++ VVDNTF TPYLQRPL FG D ++S TKY+NGH D + G I + AI
Sbjct: 184 -LVTVVDNTFCTPYLQRPLNFGIDWSVHSTTKYLNGHGDCVGGVVIGTEPAI 234
>UniRef50_A7DB98 Cluster: Cystathionine gamma-synthase; n=2;
Methylobacterium extorquens PA1|Rep: Cystathionine
gamma-synthase - Methylobacterium extorquens PA1
Length = 405
Score = 139 bits (336), Expect = 9e-32
Identities = 79/191 (41%), Positives = 108/191 (56%), Gaps = 3/191 (1%)
Frame = +2
Query: 200 AVVTPIVTSTTFKQPAP-AEHTGFEYGRSGNPTRNTLEECLAALDGGKYG-LTFASXXXX 373
AVV P+ STT+ + A A +GF Y R N T E+ +AAL+ + G L F S
Sbjct: 43 AVVPPLHLSTTYLRDADNAYRSGFVYARPDNATTREAEDVIAALERAEAGALLFGSGMAA 102
Query: 374 XXXXXXXXNHGDHIVSSDDVYGGTNRLLRQVIARLGINTTFTDFTNIEKVKNAMQE-NTK 550
GDH+++ + +Y G R LRQ RL + F + E V+ A++ T+
Sbjct: 103 AAAVFCALERGDHVIAPEVMYWGLRRWLRQEAPRLDLAVDFVPMDDPEAVRAAIRPGKTR 162
Query: 551 MIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQRPLXFGADIVMYSLTK 730
++WIETP NPL V DI IV+IA + G V VD+T +P L RPL GA+IVM+S TK
Sbjct: 163 LVWIETPGNPLCTVADIARIVEIAHAAG-ARVAVDSTAASPILTRPLTLGAEIVMHSATK 221
Query: 731 YMNGHSDVIMG 763
+NGHSDV+ G
Sbjct: 222 ILNGHSDVVAG 232
>UniRef50_A1A0Q5 Cluster: Cystathionine beta-lyase; n=2;
Bifidobacterium adolescentis|Rep: Cystathionine
beta-lyase - Bifidobacterium adolescentis (strain ATCC
15703 / DSM 20083)
Length = 411
Score = 139 bits (336), Expect = 9e-32
Identities = 86/229 (37%), Positives = 119/229 (51%), Gaps = 10/229 (4%)
Frame = +2
Query: 146 FATIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPAPAEHTGFEYGRSGNPTRNTLEECLAA 325
F T +H G N+ AV PI S+T+ + ++Y RSGNPTR LE+ +A
Sbjct: 4 FNTQLVH-GLPVNDNNTGAVNPPIYNSSTYAFESVGTMPRWDYARSGNPTREFLEKQIAQ 62
Query: 326 LDGGKYGLTFASXXXXXXXXXXXXNHGDHIVSSDDVYGGTNRLLRQVIARLGI---NTTF 496
L+ G G F S GD I+ ++YGGT L + R G+
Sbjct: 63 LEHGTRGFAFGSGLAAIHAVLSIFQPGDRIIVGKNIYGGTYSLFHEYFERWGVIVEEVGT 122
Query: 497 TDFTNI------EKVK-NAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVD 655
TD+ + E K NA K ++ E TNPLL+V ++ AI IA G I +VD
Sbjct: 123 TDYKALDAAVSGESAKGNAHGCPAKAVYFEVLTNPLLQVNNVTAIAGIAHRHG-AIAIVD 181
Query: 656 NTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVNDKAIGXKL 802
NTF+TPYLQ+PL GADIV++S TKY+ GHS+V G +V D +G ++
Sbjct: 182 NTFVTPYLQQPLDQGADIVIHSATKYLAGHSEVNAGLVVVKDDELGKRV 230
>UniRef50_Q4PK57 Cluster: Predicted cystathionine beta-lyase; n=1;
uncultured bacterium MedeBAC49C08|Rep: Predicted
cystathionine beta-lyase - uncultured bacterium
MedeBAC49C08
Length = 262
Score = 137 bits (332), Expect = 3e-31
Identities = 62/127 (48%), Positives = 92/127 (72%), Gaps = 1/127 (0%)
Frame = +2
Query: 404 GDHIVSSDDVYGGTNRLLRQVIA-RLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNP 580
GDHI++ DD+YGGT RL ++ + GI ++ D + + ++ +++ NTKM++ ETPTNP
Sbjct: 20 GDHIIAMDDLYGGTVRLFNEIKSISQGIEISYVDMSKEKNIEASIKPNTKMLFAETPTNP 79
Query: 581 LLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIM 760
LLK++D+E + ARS+ +II V DNTF +PY+QRPL G D V++S TKY+ GHSDVIM
Sbjct: 80 LLKIIDLEKLADFARSK-NIITVADNTFCSPYIQRPLTKGFDYVIHSATKYLCGHSDVIM 138
Query: 761 GAAIVND 781
G ++ D
Sbjct: 139 GVLVMKD 145
>UniRef50_A5KK19 Cluster: Putative uncharacterized protein; n=1;
Ruminococcus torques ATCC 27756|Rep: Putative
uncharacterized protein - Ruminococcus torques ATCC
27756
Length = 388
Score = 137 bits (332), Expect = 3e-31
Identities = 83/218 (38%), Positives = 116/218 (53%), Gaps = 9/218 (4%)
Frame = +2
Query: 146 FATIAIHAGQEPEKWNSAAVVTPI--VTSTTFKQPAPA------EHTGFEYGRSGNPTRN 301
F TI +HAGQE + A PI TS F A A + G YGR N T+
Sbjct: 6 FDTIQLHAGQERPDPATDARAVPIYATTSYVFHDCADAAARFGLQAEGNIYGRLTNSTQE 65
Query: 302 TLEECLAALDGGKYGLTFASXXXXXXXXXXX-XNHGDHIVSSDDVYGGTNRLLRQVIARL 478
E+ +AAL+GG L AS +G HIVS +YGG+ LL + L
Sbjct: 66 VFEKRIAALEGGSAALAVASGAAAITYTLQALAQNGGHIVSQKTIYGGSYNLLAHTLPNL 125
Query: 479 GINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDN 658
GI +F D ++E V+ A+ E TK ++IET NP + D++A+ ++A + I +VVDN
Sbjct: 126 GITASFVDIHDLEAVERAITEQTKALYIETLGNPNCDIPDMDALAELAH-KYQIPLVVDN 184
Query: 659 TFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAI 772
TF TPY RP+ GADIV++S TK++ GH + G +
Sbjct: 185 TFGTPYWIRPIEHGADIVVHSATKFIGGHGTTLGGVIV 222
>UniRef50_A5G8H3 Cluster: O-acetylhomoserine
aminocarboxypropyltransferase; n=3; Geobacter|Rep:
O-acetylhomoserine aminocarboxypropyltransferase -
Geobacter uraniumreducens Rf4
Length = 428
Score = 137 bits (332), Expect = 3e-31
Identities = 84/221 (38%), Positives = 119/221 (53%), Gaps = 9/221 (4%)
Frame = +2
Query: 137 KPGFATIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPAPAE--------HTGFEYGRSGNP 292
K F T+ IH G EP + A PIV S++F Q E G Y R GNP
Sbjct: 18 KYSFDTLLIHGGLEPGP--AGATTVPIVQSSSFAQATAEELEDIFRGRKVGQVYTRVGNP 75
Query: 293 TRNTLEECLAALDGGKYGLTFASXXXXXXXXXXXX-NHGDHIVSSDDVYGGTNRLLRQVI 469
T +LE+ LA L+GG+ + AS GD I++S ++GGT L R +
Sbjct: 76 TTESLEKRLALLEGGQAAIATASGMAAITTAVMTIVRSGDEILASSSLFGGTFSLFRDTL 135
Query: 470 ARLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVV 649
+ GI+TTF D T++ V+N + + T+++++ET NP + V DI AI IAR+ G I ++
Sbjct: 136 SGYGISTTFVDPTDLAAVRNGINDRTRLVFVETIGNPKMDVPDIPAIALIARAAG-IPLL 194
Query: 650 VDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAI 772
VD T TP L R GADIV++S +K++NG I G I
Sbjct: 195 VDATVTTPCLARGSDLGADIVIHSTSKFINGTGSAIGGVII 235
>UniRef50_Q7X137 Cluster: Cystathionine gamma lyase-like protein;
n=1; Pseudomonas fluorescens|Rep: Cystathionine gamma
lyase-like protein - Pseudomonas fluorescens
Length = 381
Score = 137 bits (331), Expect = 3e-31
Identities = 74/200 (37%), Positives = 111/200 (55%), Gaps = 1/200 (0%)
Frame = +2
Query: 206 VTPIVTSTTFKQPAPAEHTGFEYGRSGNPTRNTLEECLAALDGGKYGLTFASXXXXXXXX 385
VTPI + F + + F Y R NP LE+ +AAL+G +Y L +++
Sbjct: 21 VTPIYQCSAF-----SADSAFFYSRKANPNVTELEQVVAALEGSEYALAYSTGMSAIYMV 75
Query: 386 XXXXNHGDHIVSSDDVYGGTNRLLRQVIARLGINTTFTDFTNIEKVKNAMQENTKMIWIE 565
G +V + +YG + +L ++ AR+G T D T +K + + M+ E
Sbjct: 76 LELLKPGGSLVINKYIYGCSYKLFQRYAARIGAKLTILDLTTESGLKE-LPSDVDMVIFE 134
Query: 566 TPTNPLLKVVDIEAIVK-IARSRGDIIVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNG 742
TPTNP LK +DI A+ K + ++ +VVVDNT+ TP Q+PL FGADI +YS TKY +G
Sbjct: 135 TPTNPFLKDIDIHAVSKAVKQNNPHALVVVDNTWATPIFQKPLNFGADISLYSATKYFSG 194
Query: 743 HSDVIMGAAIVNDKAIGXKL 802
HSDV+ G +VN++ I +L
Sbjct: 195 HSDVMGGLVLVNNEMIYTRL 214
>UniRef50_Q89XR2 Cluster: O-acetylhomoserine sulfhydrylase; n=24;
cellular organisms|Rep: O-acetylhomoserine sulfhydrylase
- Bradyrhizobium japonicum
Length = 433
Score = 136 bits (330), Expect = 5e-31
Identities = 79/216 (36%), Positives = 115/216 (53%), Gaps = 9/216 (4%)
Frame = +2
Query: 152 TIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPAP--------AEHTGFEYGRSGNPTRNTL 307
TIAIHAG EPE + AV PI + + + E GF Y R NPT L
Sbjct: 5 TIAIHAGYEPEA-TTHAVAVPIYQTAAYAFDSADHGAALFNLEAEGFRYSRIANPTSAVL 63
Query: 308 EECLAALDGGKYGLTFASXXXXXXXXXXX-XNHGDHIVSSDDVYGGTNRLLRQVIARLGI 484
E+ ++ L+GG L A+ +HG +IVS +YG T+ LL ++ R GI
Sbjct: 64 EKRISQLEGGVGALAVATGQAALHFAFVNVADHGGNIVSVPQLYGTTHTLLSHILPRQGI 123
Query: 485 NTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTF 664
F + + ++ + ENT+ ++ ET NP V DIEA+ KIA + G + ++VDNT
Sbjct: 124 TGRFAESDKPDAIEKLIDENTRAVFAETIGNPAGNVCDIEALAKIAHAHG-VPLIVDNTV 182
Query: 665 LTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAI 772
TP L +P +GADI ++SLTK++ GH + GA +
Sbjct: 183 ATPILLKPFDYGADIAVHSLTKFLGGHGTTLGGAIV 218
>UniRef50_A6LZ85 Cluster: O-acetylhomoserine
aminocarboxypropyltransferase; n=2; Clostridium|Rep:
O-acetylhomoserine aminocarboxypropyltransferase -
Clostridium beijerinckii NCIMB 8052
Length = 434
Score = 136 bits (330), Expect = 5e-31
Identities = 84/232 (36%), Positives = 117/232 (50%), Gaps = 11/232 (4%)
Frame = +2
Query: 110 MADHGFLKQKPGFATIAIHAGQEP-EKWNSAAVVTPIVTSTTFK--------QPAPAEHT 262
M+ + + GF T +HAG P E + S AV PI + F+ +
Sbjct: 1 MSYEAYKNNQLGFTTRQLHAGYNPAEHYRSKAV--PIYQTAAFELGDVERCIRLFDYSEE 58
Query: 263 GFEYGRSGNPTRNTLEECLAALDGGKYGLTFASXXXXXXXXXXX-XNHGDHIVSSDDVYG 439
G Y R NPT LE LA+L+GG + S GD IV+ + +YG
Sbjct: 59 GHSYVRFSNPTNTVLERRLASLEGGIEAIALGSGMAAISNTFLNIAKSGDEIVAVNTLYG 118
Query: 440 GTNRLLRQVIARLGINTTFTDFTN-IEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVK 616
G+ LL ++ GI F + N IE + + E TK I+ E+ NP + ++DIEA+
Sbjct: 119 GSTTLLNSILPDYGIVGRFVEDENDIESYRKVITEKTKAIYSESLGNPGMNIIDIEAVAN 178
Query: 617 IARSRGDIIVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAI 772
+A G I ++VDNTF TPYL RP +GADIV YS TKY+ GH I+GA +
Sbjct: 179 LAHEHG-IPLIVDNTFATPYLLRPFEYGADIVCYSATKYLAGHGTTIVGAVV 229
>UniRef50_A4FF27 Cluster: Methionine gamma-lyase; n=1;
Saccharopolyspora erythraea NRRL 2338|Rep: Methionine
gamma-lyase - Saccharopolyspora erythraea (strain NRRL
23338)
Length = 396
Score = 136 bits (330), Expect = 5e-31
Identities = 66/178 (37%), Positives = 103/178 (57%), Gaps = 1/178 (0%)
Frame = +2
Query: 254 EHTGFEYGRSGNPTRNTLEECLAALDGGKYGLTFASXXXXXXXXXXXX-NHGDHIVSSDD 430
E F Y R GNPT + LE+ +A L+GG L AS + GDH+++
Sbjct: 50 EPEAFVYNRYGNPTVDALEKAVAGLEGGAAALAAASGMGAISTVLLGSLSSGDHVIAQRG 109
Query: 431 VYGGTNRLLRQVIARLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAI 610
+YG T LL + R G+ T ++E+++ A++ NTK++++ET NP ++ D+ +
Sbjct: 110 LYGATLALLADLAQRWGVEVTHASGHDVEEMRAALRPNTKLLYLETIGNPTTRIADLPGL 169
Query: 611 VKIARSRGDIIVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVNDK 784
+AR G ++ VVDNTF TP L RP+ GAD+V++S TKY+ GH D + G A+ D+
Sbjct: 170 FAVAREHG-VMSVVDNTFATPVLCRPIEHGADVVVHSTTKYIGGHGDTLGGIAVFADR 226
>UniRef50_Q5QWY7 Cluster: Cystathionine gamma-synthase; n=5;
Proteobacteria|Rep: Cystathionine gamma-synthase -
Idiomarina loihiensis
Length = 383
Score = 136 bits (328), Expect = 8e-31
Identities = 74/206 (35%), Positives = 113/206 (54%), Gaps = 3/206 (1%)
Frame = +2
Query: 194 SAAVVTPIVTSTTFKQPAPAEH-TGFEYGRSGNPTRNTLEECLAALDGGKYGLTFASXXX 370
+ ++ P+ TSTT+ + ++ +G Y R+ NPT E+ LA L+ FAS
Sbjct: 23 NGVIIPPVYTSTTYLRDDDNQYRSGRVYSRADNPTYRPAEKLLAELENAADARLFASGMA 82
Query: 371 XXXXXXXXXNHGDHIVSSDDVYGGTNRLLRQVIARLGINTTFTDFTNIEKVKNAMQENTK 550
GD +++ +Y + L+ G++ F D TN+ ++++A+ E
Sbjct: 83 AATAVFQALKPGDKVIAPKVMYWALRKWLQTFGVDSGLDVRFVDTTNLNELRDAIAERQP 142
Query: 551 -MIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQRPLXFGADIVMYSLT 727
+IW+ETP NPL V DI A+ +AR+ G ++ + D+T TP L +PL GADIVM+S T
Sbjct: 143 TLIWLETPGNPLWTVTDIAAVADMARNCGSLLAI-DSTVATPLLTKPLDLGADIVMHSAT 201
Query: 728 KYMNGHSDVIMGA-AIVNDKAIGXKL 802
KY+NGHSDVI GA A D A +L
Sbjct: 202 KYLNGHSDVISGALAAREDNAFWQRL 227
>UniRef50_Q1VZU8 Cluster: Cystathionine beta-lyase; n=12;
Bacteroidetes|Rep: Cystathionine beta-lyase -
Psychroflexus torquis ATCC 700755
Length = 405
Score = 135 bits (327), Expect = 1e-30
Identities = 74/225 (32%), Positives = 121/225 (53%), Gaps = 1/225 (0%)
Frame = +2
Query: 131 KQKPGFATIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPAPAEHTGFEYGRSGNPTRNTLE 310
K + G TI +H+G + AV +P+ ST + Y S P + L
Sbjct: 25 KMQKGLNTICVHSGDVKDTIYKGAV-SPLYMSTAYAYEGLETSIYPRYFNS--PNQYFLA 81
Query: 311 ECLAALDGGKYGLTFASXXXXXXXXXXXX-NHGDHIVSSDDVYGGTNRLLRQVIARLGIN 487
+ +A L+ + L F S GDH++ + +YGGT + + R GI+
Sbjct: 82 KKIAELEHAESALIFGSGMAAITTAMLSVLESGDHVILQNQIYGGTRNFIIEECHRYGIS 141
Query: 488 TTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFL 667
F D N+ +++ ++ TK+++IETP+NPLL++ D++ + K A+ +G I+ + DNTF
Sbjct: 142 FDFIDVNNLTLLESTVKPETKLLYIETPSNPLLEITDLKLVSKFAKEKG-ILTMADNTFA 200
Query: 668 TPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVNDKAIGXKL 802
+P QRPL G DIV++S TKY+ GHSD+ G A+ + +AI K+
Sbjct: 201 SPINQRPLDLGIDIVLHSATKYLGGHSDITAG-AVASTEAIMNKV 244
>UniRef50_Q4AEY8 Cluster: Cystathionine gamma-synthase; n=1;
Chlorobium phaeobacteroides BS1|Rep: Cystathionine
gamma-synthase - Chlorobium phaeobacteroides BS1
Length = 245
Score = 134 bits (325), Expect = 2e-30
Identities = 71/223 (31%), Positives = 118/223 (52%), Gaps = 7/223 (3%)
Frame = +2
Query: 137 KPGFATIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPAPA------EHTGFEYGRSGNPTR 298
K F T+AI + ++ +V + +S F + G+ Y R NP
Sbjct: 2 KTHFETLAIRTQLDTSQFKEHSVPIYLTSSYAFDSAEEGAEIFANQRDGYYYSRVANPNS 61
Query: 299 NTLEECLAALDGGKYGLTFASXXXXXXXXXXXX-NHGDHIVSSDDVYGGTNRLLRQVIAR 475
+ L E +A L+G + G++ A+ GDH+++S ++G + L+ ++
Sbjct: 62 DELAEKMALLEGAESGISTATGMAAIFSVFGALLKKGDHLLASSSIFGSSRHLIENILPN 121
Query: 476 LGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVD 655
GI F ++ +NA NTKM+++ETP NP L ++D++ + ++ +G I+VVD
Sbjct: 122 WGIEHEFVGIKDMHAWENAFHPNTKMVFVETPANPTLDLIDLKYLAELCYQKG-AILVVD 180
Query: 656 NTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVNDK 784
N F TPYLQ+PL FGAD+V++S TKY++G V +G IV K
Sbjct: 181 NCFATPYLQQPLSFGADLVVHSATKYIDGQGRV-LGGVIVGSK 222
>UniRef50_Q67QQ8 Cluster: Cystathionine gamma-lyase; n=1;
Symbiobacterium thermophilum|Rep: Cystathionine
gamma-lyase - Symbiobacterium thermophilum
Length = 395
Score = 133 bits (322), Expect = 4e-30
Identities = 77/215 (35%), Positives = 115/215 (53%), Gaps = 8/215 (3%)
Frame = +2
Query: 152 TIAIHAGQEPEKWNSAAVVTPIVTST-TFKQPAPA------EHTGFEYGRSGNPTRNTLE 310
T+A HAG +P ++ AA TST F+ A A E + Y R NPT +E
Sbjct: 14 TLAAHAGDDPFRFLGAAAPPIFETSTFVFRTVADALAAFADEQEHYVYTRRRNPTVRVVE 73
Query: 311 ECLAALDGGKYGLTFASXXXXXXXXXXX-XNHGDHIVSSDDVYGGTNRLLRQVIARLGIN 487
E LAAL+G FAS GDH+V D YG + ++R GI+
Sbjct: 74 EKLAALEGAAECRLFASGMAAISAAILSCVGAGDHVVCVDTAYGPARAFITGYLSRFGIS 133
Query: 488 TTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFL 667
T D + + + A++ NT++ ++E+P++ L+K+ D+ A+ +AR G I + DN++
Sbjct: 134 ATLVDGCDPAEWEAAVRPNTRLFYLESPSSGLMKLQDLAAVTALARRHG-IATICDNSYA 192
Query: 668 TPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAI 772
T LQRPL G D+V+YS +KY GHSDV+ GA +
Sbjct: 193 TMLLQRPLELGVDLVVYSCSKYFGGHSDVLAGAVL 227
>UniRef50_Q28Q09 Cluster: Cystathionine gamma-synthase; n=7;
Rhodobacterales|Rep: Cystathionine gamma-synthase -
Jannaschia sp. (strain CCS1)
Length = 396
Score = 133 bits (322), Expect = 4e-30
Identities = 77/205 (37%), Positives = 109/205 (53%), Gaps = 9/205 (4%)
Frame = +2
Query: 194 SAAVVTPIVTSTTFKQPAPAE-HT-------GFEYGRSGNPTRNTLEECLAALDGGKYGL 349
S AVVTPI S + P+ A H G+ Y R G+P L + L+ GL
Sbjct: 23 SRAVVTPIQPSVVYASPSIATLHAQYEGRAHGYTYAREGHPNAELLARKIDMLEEADGGL 82
Query: 350 TFASXXXXXXXXXXXX-NHGDHIVSSDDVYGGTNRLLRQVIARLGINTTFTDFTNIEKVK 526
S GDHIV + +YG + RL+ Q + R GI T+ D T+++ ++
Sbjct: 83 ILGSGMAAVSATILGLLGQGDHIVGGNQLYGRSLRLMHQDLGRFGIATSVADPTDVDAMR 142
Query: 527 NAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQRPLXFGAD 706
A++ TKMI +E +NP L+V D+ I+ +AR G +I+ VDNTF TP RPL GAD
Sbjct: 143 AALRPETKMILVEVISNPTLRVADMAGIIALAREVG-VILAVDNTFTTPAAYRPLVEGAD 201
Query: 707 IVMYSLTKYMNGHSDVIMGAAIVND 781
I ++S+TK + GHSDV +G D
Sbjct: 202 ITIHSVTKLLAGHSDVTLGYVAARD 226
>UniRef50_Q5NPR0 Cluster: Cystathionine beta-lyases; n=5;
Sphingomonadales|Rep: Cystathionine beta-lyases -
Zymomonas mobilis
Length = 402
Score = 132 bits (320), Expect = 7e-30
Identities = 69/184 (37%), Positives = 102/184 (55%), Gaps = 1/184 (0%)
Frame = +2
Query: 254 EHTGFEYGRSGNPTRNTLEECLAALDGGKYGLTFASXXXXXXXXXXXX-NHGDHIVSSDD 430
E G Y R +PT LEE LA ++G + T ++ + GDH V
Sbjct: 59 EQEGMIYSRMQSPTVMMLEEKLALIEGAETSRTMSTGMAAMTSVLLSALSAGDHFVIGRV 118
Query: 431 VYGGTNRLLRQVIARLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAI 610
+G L ++ R GI T D ++++ K+A+Q NTK+ + ETPTNP L++VDIEA+
Sbjct: 119 AFGSCRWLSDSLLPRFGITATVVDGADVQQWKDAIQPNTKLFFFETPTNPTLELVDIEAV 178
Query: 611 VKIARSRGDIIVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVNDKAI 790
IA+ G I+ VVDN F TP +Q+P+ FG D+V YS TK M+G V+ G+ ++K +
Sbjct: 179 CNIAKEAG-ILTVVDNAFCTPVIQKPMDFGVDVVAYSATKMMDGQGRVLAGSVAGSNKFV 237
Query: 791 GXKL 802
L
Sbjct: 238 NETL 241
>UniRef50_Q1ELY9 Cluster: Cystathionine beta-lyases/cystathionine
gamma-synthases; n=1; uncultured Thermotogales
bacterium|Rep: Cystathionine beta-lyases/cystathionine
gamma-synthases - uncultured Thermotogales bacterium
Length = 380
Score = 132 bits (320), Expect = 7e-30
Identities = 81/220 (36%), Positives = 128/220 (58%), Gaps = 4/220 (1%)
Frame = +2
Query: 143 GFATIAIHAGQEPEKWNSAAVVTPIVTSTTF---KQPAPAEHTGFEYGRSGNPTRNTLEE 313
GF T A+H G+E + ++ AV TPI ++ F + +E++ Y R GNP+ +E
Sbjct: 3 GFNTRAVHIGEERKIFD--AVSTPIFQTSNFVVDDEKYASENSETFYTRVGNPSIGVVER 60
Query: 314 CLAALDGGKYGLTFASXXXXXXXXXXXX-NHGDHIVSSDDVYGGTNRLLRQVIARLGINT 490
L+ L GG G+ F+S G ++V S ++YGGT LL + +G+
Sbjct: 61 KLSDLFGGAGGIFFSSGMGAITTIFLTFLRSGMNLVISRNIYGGTQSLLGD-LPDMGVEI 119
Query: 491 TFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLT 670
D + +E +++ + +NT ++++E+ TNP L + DI+ I I SR ++VVDNTFL+
Sbjct: 120 RRFDQSRLEGLESLVDDNTGIVYVESMTNPNLILSDIQRISHIT-SRSRALLVVDNTFLS 178
Query: 671 PYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVNDKAI 790
PY RPL +GADI + SL+KY+NGHSDVI G A ++ +
Sbjct: 179 PYNFRPLEYGADIDVQSLSKYVNGHSDVIAGFAAFRNREL 218
>UniRef50_A6W1L9 Cluster: Cystathionine gamma-synthase; n=10;
Bacteria|Rep: Cystathionine gamma-synthase - Marinomonas
sp. MWYL1
Length = 405
Score = 132 bits (320), Expect = 7e-30
Identities = 73/229 (31%), Positives = 125/229 (54%), Gaps = 9/229 (3%)
Frame = +2
Query: 143 GFATIAIHAGQEPEKWNSAAVVTPIVTSTTFKQP--------APAEHTGFEYGRSGNPTR 298
G T ++ +G++ EK A TPIV S + A GF Y R NPT
Sbjct: 14 GSGTRSVWSGEQ-EKHPYRATQTPIVASAAYGYQDIDEWYDVALGAAPGFIYSRMSNPTV 72
Query: 299 NTLEECLAALDGGKYGLTFASXXXXXXXXXXXX-NHGDHIVSSDDVYGGTNRLLRQVIAR 475
TLE + L+ + + F++ ++G +VS+ D YGGTN++ + + R
Sbjct: 73 ETLEAKICGLENAESAVAFSTGMAAISSVLYTFLSNGCRVVSTKDSYGGTNKVFEEFLPR 132
Query: 476 LGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVD 655
+G++ T + + E++++ + + ++++ETPTNP LK+VD++ +V A+ G +V+ D
Sbjct: 133 MGVSVTLCETHSHEQIEDEIAKGCDVLYLETPTNPTLKIVDVKRLVAAAKKVG-ALVMAD 191
Query: 656 NTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVNDKAIGXKL 802
NTF TP Q PL G DIV++S TK+++GH+D MG + + + K+
Sbjct: 192 NTFATPLNQSPLALGVDIVVHSATKFLSGHADA-MGGLVCGSEELMAKV 239
>UniRef50_A6NZI8 Cluster: Putative uncharacterized protein; n=1;
Bacteroides capillosus ATCC 29799|Rep: Putative
uncharacterized protein - Bacteroides capillosus ATCC
29799
Length = 429
Score = 132 bits (319), Expect = 1e-29
Identities = 83/221 (37%), Positives = 117/221 (52%), Gaps = 10/221 (4%)
Frame = +2
Query: 152 TIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPA--------PAEHTGFEYGRSGNPTRNTL 307
T IHAG P + PIV STTF+ E +G+ Y R NPT + +
Sbjct: 10 TNCIHAGYRPGNGEPRNI--PIVQSTTFRYATGEQMGALFDLEASGYFYTRLQNPTNDYV 67
Query: 308 EECLAALDGGKYG-LTFASXXXXXXXXXXXXNHGDHIVSSDDVYGGTNRLLRQVIARLGI 484
+ AL+GG LT + + GDH+V+S +YGGT L + R+GI
Sbjct: 68 AAKICALEGGTAAMLTSSGQAANFYAVFNIASCGDHVVASSAIYGGTYNLFAVTMKRMGI 127
Query: 485 NTTFTDFTNIE-KVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNT 661
TF D E +++ A + NTK ++ ET NP L V+DIE K A + G + ++VDNT
Sbjct: 128 EFTFVDPECSEAELEAAFKPNTKAVFGETIANPALTVLDIEKFAKAAHAHG-VPLIVDNT 186
Query: 662 FLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVNDK 784
F TP RP +GADIV +S TKYM+GH++ + GA + + K
Sbjct: 187 FPTPVNCRPFEWGADIVTHSTTKYMDGHANAVGGAIVDSGK 227
>UniRef50_Q1AT24 Cluster: Cystathionine gamma-synthase; n=2;
Bacteria|Rep: Cystathionine gamma-synthase - Rubrobacter
xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 410
Score = 132 bits (318), Expect = 1e-29
Identities = 85/227 (37%), Positives = 115/227 (50%), Gaps = 21/227 (9%)
Frame = +2
Query: 146 FATIAIHAGQE-PEKWNSAA------VVTPIVTSTTFKQPAP--------AEHTGFEYGR 280
F T A+HAG+ P + TPI STTF E G+ Y R
Sbjct: 11 FETRAVHAGESRPGAGGDRGGDGFYPISTPIYASTTFSHADAQTTDRVLGGEEPGYSYAR 70
Query: 281 SGNPTRNTLEECLAALD---GGKYGLTFASXXXXXXXXXXXXNHGD--HIVSSDDVYGGT 445
GNP+ LEE L AL+ GG L FAS G+ ++++D +YG T
Sbjct: 71 WGNPSVAALEEALTALEAPQGGARALAFASGMAAMHAALTAAELGEGARVLAADQLYGST 130
Query: 446 NRLLRQVIARLGINTTFTD-FTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIA 622
LL Q+ G +F D + E K + + +ET +NPLL+V DI + +I+
Sbjct: 131 ATLLLQIFGPAGTEASFFDAYDPGEAEKKVSSLRPRAVVVETISNPLLRVADIPRLAEIS 190
Query: 623 RSRGDIIVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMG 763
RS G ++V DNTF TPYLQRPL GAD+V++S TKY++GH DV G
Sbjct: 191 RSHGAALIV-DNTFGTPYLQRPLELGADMVVHSATKYLSGHGDVTAG 236
>UniRef50_A1ZIW0 Cluster: Cys/Met metabolism
pyridoxal-phosphate-dependent enzymes; n=1; Microscilla
marina ATCC 23134|Rep: Cys/Met metabolism
pyridoxal-phosphate-dependent enzymes - Microscilla
marina ATCC 23134
Length = 391
Score = 132 bits (318), Expect = 1e-29
Identities = 63/178 (35%), Positives = 106/178 (59%), Gaps = 1/178 (0%)
Frame = +2
Query: 272 YGRSGNPTRNTLEECLAALDGGKYGLTFASXXXXXXXXXXXX-NHGDHIVSSDDVYGGTN 448
Y R NPT + LE+ +AAL+ + L FAS N GDH+V Y TN
Sbjct: 52 YTRGHNPTTHILEQKMAALENAEDALVFASGSAAVAAAVIANVNQGDHVVCVQKPYSWTN 111
Query: 449 RLLRQVIARLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARS 628
+LL + R G+ T D T+ + ++A+Q NT+++++E+P + + D+ A+ +IA+
Sbjct: 112 KLLNSFLNRFGVTNTMVDGTDPQNFESAIQPNTRVLFLESPNSWTFEQQDLAAVAQIAK- 170
Query: 629 RGDIIVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVNDKAIGXKL 802
+ DI+ ++DN++ TP Q+P+ +G DIV++S TKY++GHSD + G + KA+ K+
Sbjct: 171 KHDIVTIIDNSYATPLFQKPIDYGIDIVVHSATKYISGHSDTVAG-VLCASKAMTNKI 227
>UniRef50_Q7WKX4 Cluster: Cys/Met metabolism PLP-dependent enzyme;
n=23; Proteobacteria|Rep: Cys/Met metabolism
PLP-dependent enzyme - Bordetella bronchiseptica
(Alcaligenes bronchisepticus)
Length = 414
Score = 130 bits (315), Expect = 3e-29
Identities = 73/216 (33%), Positives = 116/216 (53%), Gaps = 8/216 (3%)
Frame = +2
Query: 143 GFATIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPAPAE-------HTGFEYGRSGNPTRN 301
GF T +H+ ++ + AV P+ S+ + E GF Y R G PT
Sbjct: 5 GFTTTIVHSDRD-QSAEHGAVHKPMHPSSEYVYEDARELAAVFQGKAGFTYARQGTPTTT 63
Query: 302 TLEECLAALDGGKYGLTFASXXXXXXXXXXXX-NHGDHIVSSDDVYGGTNRLLRQVIARL 478
LE + ++ GK ++FA+ GDH+VSS V+G TN LL ++ L
Sbjct: 64 ALEARITRMEAGKSTVSFATGMAALAAIFTTLLRRGDHLVSSQYVFGNTNSLLNTLM-EL 122
Query: 479 GINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDN 658
G+ T D T++ +V++A++ NT+M++ ET NP +V D+ + + R RG ++ VVDN
Sbjct: 123 GVEVTMVDATDVRQVRDALRPNTRMVFTETIANPGTQVADLAGMGALCRERG-LVYVVDN 181
Query: 659 TFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGA 766
T +P++ RP+ GA +VM SL+KY+ GH + GA
Sbjct: 182 TLTSPWMFRPVEVGASLVMNSLSKYIAGHGHALGGA 217
>UniRef50_P55217 Cluster: Cystathionine gamma-synthase, chloroplast
precursor (EC 2.5.1.48) (CGS) (O-succinylhomoserine
(thiol)-lyase); n=30; Viridiplantae|Rep: Cystathionine
gamma-synthase, chloroplast precursor (EC 2.5.1.48)
(CGS) (O-succinylhomoserine (thiol)-lyase) - Arabidopsis
thaliana (Mouse-ear cress)
Length = 563
Score = 130 bits (315), Expect = 3e-29
Identities = 80/226 (35%), Positives = 119/226 (52%), Gaps = 11/226 (4%)
Frame = +2
Query: 119 HGFLKQKPGFATIAIHAGQEPEKWN-SAAVVTPIVTSTT--FKQPAPA------EHTGFE 271
H FL ++ +HAG+ + + A+ TP+V ++ FK+ A FE
Sbjct: 169 HSFLSSD---GSLTVHAGERLGRGIVTDAITTPVVNTSAYFFKKTAELIDFKEKRSVSFE 225
Query: 272 YGRSGNPTRNTLEECLAALDGGKYGLTFASXX-XXXXXXXXXXNHGDHIVSSDDVYGGTN 448
YGR GNPT LE+ ++AL+G + L AS G HIV++ D Y T
Sbjct: 226 YGRYGNPTTVVLEDKISALEGAESTLVMASGMCASTVMLLALVPAGGHIVTTTDCYRKTR 285
Query: 449 RLLRQVIARLGINTTFTDFTNIEKVKNAMQE-NTKMIWIETPTNPLLKVVDIEAIVKIAR 625
+ + +LGI T D +I ++ A+ E + + E+PTNP L+ VDIE + KI
Sbjct: 286 IFMENFLPKLGITVTVIDPADIAGLEAAVNEFKVSLFFTESPTNPFLRCVDIELVSKICH 345
Query: 626 SRGDIIVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMG 763
RG + V +D TF TP Q+ L GAD+V++S TKY+ GH+DV+ G
Sbjct: 346 KRGTL-VCIDGTFATPLNQKALALGADLVVHSATKYIGGHNDVLAG 390
>UniRef50_A5MZA3 Cluster: O-acetyl-L-homoserine
sulfhydrylase-related protein; n=8; Bacteria|Rep:
O-acetyl-L-homoserine sulfhydrylase-related protein -
Clostridium kluyveri DSM 555
Length = 428
Score = 130 bits (314), Expect = 4e-29
Identities = 82/218 (37%), Positives = 114/218 (52%), Gaps = 11/218 (5%)
Frame = +2
Query: 152 TIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPAPA--------EHTGFEYGRSGNPTRNTL 307
T + AG P V PI+ STTFK E +G+ Y R NPT + +
Sbjct: 8 TKCVQAGYRPGNGEPRQV--PIIQSTTFKYNTSEDMGKLFDLEASGYFYSRLQNPTNDYV 65
Query: 308 EECLAALDGGKYG-LTFASXXXXXXXXXXXXNHGDHIVSSDDVYGGTNRLLRQVIARLGI 484
+ +A ++ G LT + N GDHIV+S +YGGT L+ ++++GI
Sbjct: 66 AQKIADMESGTAAMLTSSGQAANFFALFNICNCGDHIVASSSIYGGTFNLISVTMSKMGI 125
Query: 485 NTTFT--DFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDN 658
TTF D T E++ A Q NTK ++ ET NP L V+DIE K A + D+ ++VDN
Sbjct: 126 TTTFVSPDCTE-EELNAAFQTNTKAVFGETIANPALTVLDIEKFAKAAHAH-DVPLIVDN 183
Query: 659 TFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAI 772
TF TP RP +GADIV +S TKYM+GH + G +
Sbjct: 184 TFPTPINCRPFEWGADIVTHSTTKYMDGHGAAVGGVIV 221
>UniRef50_Q8EM13 Cluster: O-acetylhomoserine sulfhydrylase; n=86;
cellular organisms|Rep: O-acetylhomoserine sulfhydrylase
- Oceanobacillus iheyensis
Length = 556
Score = 130 bits (313), Expect = 5e-29
Identities = 75/215 (34%), Positives = 113/215 (52%), Gaps = 8/215 (3%)
Frame = +2
Query: 152 TIAIHAGQEPE-KWNSAAVVTPIVTSTTFKQPAPAEHT------GFEYGRSGNPTRNTLE 310
TI +H GQEP+ S AV TS F+ A++ G Y R NPT + E
Sbjct: 11 TILLHGGQEPDPSTGSRAVPIYQTTSYVFRDTEHAQNLFGLAEPGNIYSRIMNPTVDAFE 70
Query: 311 ECLAALDGGKYGL-TFASXXXXXXXXXXXXNHGDHIVSSDDVYGGTNRLLRQVIARLGIN 487
+ + L+ G + T + GD IV+ ++YGGT L + R GIN
Sbjct: 71 QRITQLEDGIGAVATSSGMAAITLAILNIAGSGDEIVADSNLYGGTFNLFANTLPRYGIN 130
Query: 488 TTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFL 667
F D T+ + + +A+ + TK ++ E TNP L V DIE + ++A G + +++DNTF
Sbjct: 131 VKFVDGTDPQAIDDAITDKTKAVFGEIITNPSLYVFDIEKVSEVAHKHG-VPLIIDNTFA 189
Query: 668 TPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAI 772
TPY+ +PL +GADIV++S TK++ GH I G +
Sbjct: 190 TPYVTKPLTWGADIVVHSATKWIGGHGTTIGGVVV 224
>UniRef50_Q86D27 Cluster: Methionine gamma-lyase 2; n=3; Entamoeba
histolytica|Rep: Methionine gamma-lyase 2 - Entamoeba
histolytica
Length = 392
Score = 129 bits (312), Expect = 7e-29
Identities = 68/181 (37%), Positives = 97/181 (53%), Gaps = 1/181 (0%)
Frame = +2
Query: 263 GFEYGRSGNPTRNTLEECLAALDGGKYGLTFASXXXXXXXXXXXX-NHGDHIVSSDDVYG 439
G Y R GNPT EE + +L+GG F S GDH++S D +YG
Sbjct: 53 GHMYSRMGNPTVEYFEELVNSLEGGVGTAAFGSGMGAIHSATMGLLKAGDHLISGDTLYG 112
Query: 440 GTNRLLRQVIARLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKI 619
T L +G++ +F + + E V A + NTKM+++E+P NP KV DI+ I KI
Sbjct: 113 CTVELFGNRFKDMGVDVSFVNTASDEAVVKAWKPNTKMVYLESPANPTCKVSDIKGIAKI 172
Query: 620 ARSRGDIIVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVNDKAIGXK 799
+G I+VVD TF TP L GAD+V++S+TKY+NGH DV+ G + + K
Sbjct: 173 CHEKG-AILVVDCTFTTPVFLPALELGADVVLHSITKYINGHGDVVGGVVTTKNPELLQK 231
Query: 800 L 802
+
Sbjct: 232 I 232
>UniRef50_P06106 Cluster: Protein MET17 [Includes:
O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) (OAH
sulfhydrylase) (Homocysteine synthase); O- acetylserine
sulfhydrylase (EC 2.5.1.47) (OAS sulfhydrylase)]; n=107;
cellular organisms|Rep: Protein MET17 [Includes:
O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) (OAH
sulfhydrylase) (Homocysteine synthase); O- acetylserine
sulfhydrylase (EC 2.5.1.47) (OAS sulfhydrylase)] -
Saccharomyces cerevisiae (Baker's yeast)
Length = 444
Score = 129 bits (312), Expect = 7e-29
Identities = 84/224 (37%), Positives = 113/224 (50%), Gaps = 11/224 (4%)
Frame = +2
Query: 146 FATIAIHAGQEPEKWNS-AAVVTPIVTSTTF--------KQPAPAEHTGFEYGRSGNPTR 298
F T+ +HAGQE N+ + PI +T++ Q E G+ Y R NPT
Sbjct: 5 FDTVQLHAGQENPGDNAHRSRAVPIYATTSYVFENSKHGSQLFGLEVPGYVYSRFQNPTS 64
Query: 299 NTLEECLAALDGGKYGLTFASXXXXXXXXXXXXNH-GDHIVSSDDVYGGTNRLLRQVIAR 475
N LEE +AAL+GG L +S H GD+IVS+ +YGGT + R
Sbjct: 65 NVLEERIAALEGGAAALAVSSGQAAQTLAIQGLAHTGDNIVSTSYLYGGTYNQFKISFKR 124
Query: 476 LGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVD 655
GI F + N E+ + E TK +++ET NP V D E IV IA G I VVVD
Sbjct: 125 FGIEARFVEGDNPEEFEKVFDERTKAVYLETIGNPKYNVPDFEKIVAIAHKHG-IPVVVD 183
Query: 656 NTF-LTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVNDK 784
NTF Y +P+ +GADIV +S TK++ GH I G + + K
Sbjct: 184 NTFGAGGYFCQPIKYGADIVTHSATKWIGGHGTTIGGIIVDSGK 227
>UniRef50_A5WGJ5 Cluster: O-acetylhomoserine/O-acetylserine
sulfhydrylase; n=142; Bacteria|Rep:
O-acetylhomoserine/O-acetylserine sulfhydrylase -
Psychrobacter sp. PRwf-1
Length = 437
Score = 129 bits (311), Expect = 9e-29
Identities = 83/225 (36%), Positives = 114/225 (50%), Gaps = 10/225 (4%)
Frame = +2
Query: 128 LKQKPGFATIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPAPAEH---------TGFEYGR 280
L+ T+AIHAG E + AV PI ++++ +H G Y R
Sbjct: 11 LENNQRLETLAIHAGYSVEP-TTKAVAVPIYHTSSYAFD-DTQHGADLFDLKVAGNIYTR 68
Query: 281 SGNPTRNTLEECLAALDGGKYGLTFASXXXXXXXXXXXX-NHGDHIVSSDDVYGGTNRLL 457
NPT LEE +AAL+GG L AS GD+I+++ +YGGT
Sbjct: 69 IMNPTNAVLEERVAALEGGIGALAVASGMAAITYAVQTICEAGDNIIAASTLYGGTYNFF 128
Query: 458 RQVIARLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGD 637
+ R GI F D N + + + E TKM++ E+ NPL ++DIEAI A G
Sbjct: 129 AHTLPRQGIEVRFFDHKNPAAIHDLVDEKTKMVFAESIGNPLGNIIDIEAIADAAHKHG- 187
Query: 638 IIVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAI 772
+ VV+DNT TP + RP FGADIV++SLTKYM+G I GA +
Sbjct: 188 VPVVIDNTVATPAICRPFEFGADIVVHSLTKYMSGTGTSIGGAIV 232
>UniRef50_Q97CC7 Cluster: Cystathionine beta lyase /
O-succinylhomoserine lyase; n=5; Thermoplasmatales|Rep:
Cystathionine beta lyase / O-succinylhomoserine lyase -
Thermoplasma volcanium
Length = 394
Score = 128 bits (310), Expect = 1e-28
Identities = 93/248 (37%), Positives = 136/248 (54%), Gaps = 13/248 (5%)
Frame = +2
Query: 98 NKIGMADHGFLKQKPGFATIAIHAGQ--EPEKWNSAAVVTPIVTSTTFKQP-----APAE 256
NK+ MA+ GF T A+ +G+ +P N V TPI ++TF P A +
Sbjct: 2 NKVRMAEKRLFN---GFNTRAVQSGELRDPRFGN---VTTPIFETSTFVFPNSEKDAYID 55
Query: 257 HTG---FEYGRSGNPTRNTLEECLAALDGGKYGLTFASXXXXXXXXXXX-XNHGDHIVSS 424
+T + Y R GNPT EE A+L+ ++ L+F+S GD I+S
Sbjct: 56 NTRNLPYIYTRWGNPTVQAFEEKYASLEKAEHALSFSSGMGAITSVILALAERGDKILSV 115
Query: 425 DDVYGGTNRLLRQVIARLGINTTF--TDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVD 598
D+YG T L +V+ GI+ + TD N + K + + +I++E+ TNP LKV D
Sbjct: 116 SDLYGQTFYFLNKVLPEYGISVEYISTDRLNSGEFKPSDYD---IIYLESITNPTLKVPD 172
Query: 599 IEAIVKIARSRGDIIVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVN 778
I+A+ + RS G I+V D TF +PY Q PL GAD+V++S TKY++GHSDV+MG N
Sbjct: 173 IKAVSE--RSTGKKIIV-DATFASPYNQNPLDLGADVVIHSATKYISGHSDVVMGVFSTN 229
Query: 779 DKAIGXKL 802
DK+I K+
Sbjct: 230 DKSIFDKV 237
>UniRef50_Q8RI68 Cluster: Cystathionine gamma-synthase; n=1;
Fusobacterium nucleatum subsp. nucleatum|Rep:
Cystathionine gamma-synthase - Fusobacterium nucleatum
subsp. nucleatum
Length = 396
Score = 128 bits (309), Expect = 2e-28
Identities = 70/198 (35%), Positives = 108/198 (54%), Gaps = 1/198 (0%)
Frame = +2
Query: 176 EPEKWNSAAVVTPIVTSTTFKQPAPAEHTGFEYGRSGNPTRNTLEECLAALDGGKYGLTF 355
+PE + + S T + A AE + Y R+ NP R+ L + + L+ G+ L F
Sbjct: 25 KPEAFPLFTTTAFTMNSLTEVKKAYAEK--YTYIRTCNPNRDALADMVTFLEAGEKSLIF 82
Query: 356 ASXXXXXXXXXXXX-NHGDHIVSSDDVYGGTNRLLRQVIARLGINTTFTDFTNIEKVKNA 532
+S GDH+V + ++YG T + +++ + GI+ DF +IE K A
Sbjct: 83 SSGMGAITTTIMTILKPGDHVVCNRNIYGETFDVFTKLMPKFGISADLVDFDDIENCKKA 142
Query: 533 MQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQRPLXFGADIV 712
++ TK+I+ E NP L + DI + IA G ++++DNTF TP +P+ FGADIV
Sbjct: 143 IKAETKLIYSEVFANPTLNIADIPTLADIAHKNG-ALLMIDNTFSTPIAIKPIKFGADIV 201
Query: 713 MYSLTKYMNGHSDVIMGA 766
+ SLTK+MNGHSD I G+
Sbjct: 202 INSLTKFMNGHSDAIAGS 219
>UniRef50_Q1IZN0 Cluster: Cystathionine gamma-synthase; n=1;
Deinococcus geothermalis DSM 11300|Rep: Cystathionine
gamma-synthase - Deinococcus geothermalis (strain DSM
11300)
Length = 394
Score = 128 bits (309), Expect = 2e-28
Identities = 77/213 (36%), Positives = 113/213 (53%), Gaps = 9/213 (4%)
Frame = +2
Query: 152 TIAIHAGQEPEKWNSAAVVTPIVTSTTFKQP----APAEHTGFE----YGRSGNPTRNTL 307
T+A AG+E S + PI ST + P TG E Y R+G P TL
Sbjct: 10 TLAARAGEEARPNASVPLAEPIYQSTVYAFPDLDALERSMTGEEASSFYYRNGTPNAGTL 69
Query: 308 EECLAALDGGKYGLTFASXXXXXXXXXXXX-NHGDHIVSSDDVYGGTNRLLRQVIARLGI 484
E LA L+G + L S GDHIV+ VYG T LL + + RLGI
Sbjct: 70 ERVLATLEGTEAALVAGSGMAAISAALLGVLKSGDHIVADARVYGVTYALLAEELPRLGI 129
Query: 485 NTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTF 664
T+F D ++ V+ A + T+++ +E+ TNPL+ V D+ + +A +RG ++ VDNTF
Sbjct: 130 TTSFVDACDLGAVEAAFRPETRVLHVESLTNPLMTVPDVPRLADLAHARG-ALLSVDNTF 188
Query: 665 LTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMG 763
+P + RP GAD+V +S++KY++GHS+ G
Sbjct: 189 ASPAVFRPATHGADLVTHSVSKYLSGHSNAFGG 221
>UniRef50_A7INF9 Cluster: O-acetylhomoserine
aminocarboxypropyltransferase; n=2;
Alphaproteobacteria|Rep: O-acetylhomoserine
aminocarboxypropyltransferase - Xanthobacter sp. (strain
Py2)
Length = 467
Score = 128 bits (309), Expect = 2e-28
Identities = 81/221 (36%), Positives = 114/221 (51%), Gaps = 9/221 (4%)
Frame = +2
Query: 137 KPGFATIAIHAGQEPEKWNSAAVVTPIVTSTTFK----QPAPA----EHTGFEYGRSGNP 292
+PGFAT+AIHAG +P+ + A TPI +T+F A A + G Y R NP
Sbjct: 11 EPGFATLAIHAGAQPDP-TTGARATPIYQTTSFVFDDVDHAAALFGLQTFGNIYSRITNP 69
Query: 293 TRNTLEECLAALDGGKYGLTFASXXXXXXXXXXXX-NHGDHIVSSDDVYGGTNRLLRQVI 469
T LEE +AAL+GG L AS GD ++S +YGG+
Sbjct: 70 TNAVLEERVAALEGGTAALAVASGHAAQHLVFHTLLTPGDEFIASRKLYGGSINQFNHAF 129
Query: 470 ARLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVV 649
G N + D +I + A+ TK I+ E+ NP V DI AI +A+ G + ++
Sbjct: 130 KSFGWNVVWADPDDISSFEKAVTPKTKAIFTESIANPGGVVTDIAAISAVAKKAG-VPLI 188
Query: 650 VDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAI 772
VDNT TPYL +P+ GADIV++S TK++ GH + I G +
Sbjct: 189 VDNTLATPYLWQPIRHGADIVIHSATKFLGGHGNSIGGVIV 229
>UniRef50_UPI0000E46EAD Cluster: PREDICTED: similar to methionine
gamma-lyase; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to methionine gamma-lyase -
Strongylocentrotus purpuratus
Length = 364
Score = 128 bits (308), Expect = 2e-28
Identities = 62/174 (35%), Positives = 95/174 (54%), Gaps = 1/174 (0%)
Frame = +2
Query: 263 GFEYGRSGNPTRNTLEECLAALDGGKYGLTFASXXXXXXXXXXXX-NHGDHIVSSDDVYG 439
G+ YGR GN + + + L+GG L F++ GDH+++ D V+G
Sbjct: 87 GYIYGRYGNHSCDNASHAINILEGGIGALVFSTGMSAITTTVLALIKTGDHVIAPDPVFG 146
Query: 440 GTNRLLRQVIARLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKI 619
GT + ++ G+ TTF +IE + A+Q NTK+ + ETPTNP L ++D++A +
Sbjct: 147 GTYKFFNSMLMDFGVETTFVPAGDIEAYRKAIQPNTKIFYGETPTNPTLTLLDLKAFADV 206
Query: 620 ARSRGDIIVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVND 781
A+S I + D+TF TPYLQ L G DI S +KY+ GH D++ G+ D
Sbjct: 207 AKSVPGAISMSDSTFATPYLQDTLGLGVDISFQSCSKYLGGHGDLLGGSMCTKD 260
>UniRef50_Q67KY0 Cluster: O-acetylhomoserine sulfhydrylase; n=28;
cellular organisms|Rep: O-acetylhomoserine sulfhydrylase
- Symbiobacterium thermophilum
Length = 435
Score = 127 bits (306), Expect = 4e-28
Identities = 79/219 (36%), Positives = 111/219 (50%), Gaps = 9/219 (4%)
Frame = +2
Query: 149 ATIAIHAGQEPEKWNSAAVVTPIVTSTTF--------KQPAPAEHTGFEYGRSGNPTRNT 304
AT+ +HAG +P+ A V PI +T + +Q E G Y R NPT
Sbjct: 15 ATLVVHAGWQPDPLTGAQAV-PIYQTTAYAFQSTEHARQLFSLEAEGNIYTRINNPTTAA 73
Query: 305 LEECLAALDGGKYGLTFASXXXXXXXXXXXX-NHGDHIVSSDDVYGGTNRLLRQVIARLG 481
E +AAL+GG + FAS N GD IV+S +YGGT L + + G
Sbjct: 74 FEARVAALEGGIGAVAFASGHAALAATVLAICNAGDEIVTSSSLYGGTYNLFATTLPKWG 133
Query: 482 INTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNT 661
I F D ++ A+ T++I+ E NP L V DI + IA G + +V+DNT
Sbjct: 134 ITARFVDAHDLAGFHRAITPRTRLIFGEVIGNPRLDVFDIAGVAAIAHEHG-LPLVIDNT 192
Query: 662 FLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVN 778
F TP L RP+ GAD+V++S TK++ GH V MG +V+
Sbjct: 193 FATPMLCRPIEHGADLVIHSATKWLGGHG-VAMGGVVVD 230
>UniRef50_P55218 Cluster: O-succinylhomoserine sulfhydrylase; n=95;
Proteobacteria|Rep: O-succinylhomoserine sulfhydrylase -
Pseudomonas aeruginosa
Length = 403
Score = 127 bits (306), Expect = 4e-28
Identities = 76/208 (36%), Positives = 116/208 (55%), Gaps = 9/208 (4%)
Frame = +2
Query: 146 FATIAIHAGQE--PEKWNSAAVVTPIVTSTTFKQPAPA------EHTGFEYGRSGNPTRN 301
F T+A+ AGQ PE + A+ T +S F+ A A E G Y R NPT
Sbjct: 19 FDTLAVRAGQRRTPEGEHGEALFT--TSSYVFRTAADAAARFAGEVPGNVYSRYTNPTVR 76
Query: 302 TLEECLAALDGGKYGLTFASXXXXXXXXXXXX-NHGDHIVSSDDVYGGTNRLLRQVIARL 478
T EE +AAL+G + + AS + GDH++ S V+G T L + R
Sbjct: 77 TFEERIAALEGAEQAVATASGMSAILALVMSLCSSGDHVLVSRSVFGSTISLFDKYFKRF 136
Query: 479 GINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDN 658
GI + +++ + A + NTK+ ++E+P+NPL ++VDI A+ +IA ++G ++ VDN
Sbjct: 137 GIQVDYPPLSDLAAWEAACKPNTKLFFVESPSNPLAELVDIAALAEIAHAKG-ALLAVDN 195
Query: 659 TFLTPYLQRPLXFGADIVMYSLTKYMNG 742
F TP LQ+PL GAD+V++S TKY++G
Sbjct: 196 CFCTPALQQPLKLGADVVIHSATKYIDG 223
>UniRef50_Q338K0 Cluster: Cys/Met metabolism PLP-dependent enzyme
family protein; n=7; Oryza sativa|Rep: Cys/Met
metabolism PLP-dependent enzyme family protein - Oryza
sativa subsp. japonica (Rice)
Length = 433
Score = 126 bits (304), Expect = 6e-28
Identities = 76/219 (34%), Positives = 118/219 (53%), Gaps = 15/219 (6%)
Frame = +2
Query: 152 TIAIHAGQEPEKWNSAA----VVTPIVTSTT--FKQPAP------AEHTGFEYGRSGNPT 295
T+A+HAG++ +AA + TPIV TT F+ A FEYGR GNPT
Sbjct: 83 TLAVHAGEKLGSGAAAAETDSIATPIVGGTTHWFRDSADLIAFREGRRRSFEYGRYGNPT 142
Query: 296 RNTLEECLAALDGGKYGL-TFASXXXXXXXXXXXXNHGDHIVSSDDVYGGTNRLLRQVIA 472
LEE ++AL+ + L T + G H+V++ D Y +R ++
Sbjct: 143 VKVLEEKISALERAEATLVTSSGMNAIVATLLALVPPGGHVVATADCYSEARAFIRDKLS 202
Query: 473 RLGINTTFTDFTN-IEKVKNAMQEN-TKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIV 646
+GI +TF D + +E +++ + E M + ++ TNP LKVVD+ + ++ RG +V
Sbjct: 203 NMGITSTFVDLDDDMEALESVLDEGEVTMFYADSMTNPHLKVVDVTRVAELCHRRG-ALV 261
Query: 647 VVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMG 763
+D+T +P Q+PL GAD+V++S TKY+ GH DVI G
Sbjct: 262 CIDSTLASPINQKPLALGADVVLHSATKYIAGHHDVIAG 300
>UniRef50_Q0B7N7 Cluster: Cystathionine gamma-synthase; n=4;
Betaproteobacteria|Rep: Cystathionine gamma-synthase -
Burkholderia cepacia (strain ATCC 53795 / AMMD)
Length = 389
Score = 125 bits (301), Expect = 1e-27
Identities = 64/178 (35%), Positives = 98/178 (55%), Gaps = 1/178 (0%)
Frame = +2
Query: 272 YGRSGNPTRNTLEECLAALDGGKYGLTFASXXXXXXXXXXXX-NHGDHIVSSDDVYGGTN 448
Y R GNP ++ +A L+G + L AS GDH+V Y T
Sbjct: 53 YTRYGNPVHERVKAIMAELEGTETALVTASGMGAIATAILSVVKAGDHVVGQTRHYMSTT 112
Query: 449 RLLRQVIARLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARS 628
++L ++ R G+ TF D T++ A++ NT++I +E+P NPLL V DI A+ +IAR+
Sbjct: 113 KMLDDMLRRFGVEVTFVDQTDVAAFDRAIRPNTRLIVLESPVNPLLLVTDIGAVTEIARA 172
Query: 629 RGDIIVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVNDKAIGXKL 802
RG I+ + DNTF +P Q+P G DIV++S TKY+ GH D + G I + + ++
Sbjct: 173 RG-ILTLADNTFASPVNQQPHRLGVDIVVHSATKYLGGHHD-LTGGVICTSRVLAEQI 228
>UniRef50_A4AND2 Cluster: Cystathionine gamma-lyase; n=2; cellular
organisms|Rep: Cystathionine gamma-lyase -
Flavobacteriales bacterium HTCC2170
Length = 396
Score = 125 bits (301), Expect = 1e-27
Identities = 67/182 (36%), Positives = 104/182 (57%), Gaps = 2/182 (1%)
Frame = +2
Query: 251 AEHTGFEYGRSGNPTRNTLEECLAALDGGKYGLTFASXXXXXXXX-XXXXNHGDHIVSSD 427
+EH F Y R NPT +EE +A L G+ F S DH+V+
Sbjct: 51 SEH--FIYSRGKNPTVKLVEEKIALLANGEKAQLFPSGMAAITASCLHFLRPNDHVVAIK 108
Query: 428 DVYGGTNRLLRQVIAR-LGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIE 604
++YG + LL+ +++ + I TTF +IE ++A++ENT +I++E+P+ + + DIE
Sbjct: 109 NLYGPASNLLKSYLSKKMNIETTFVSGEHIEDFEDAIRENTALIYLESPSTAVFSLQDIE 168
Query: 605 AIVKIARSRGDIIVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVNDK 784
AI +ARS+G I ++DNT TP Q+PL G D+ ++S TKY+ GHSD+I G I K
Sbjct: 169 AIANLARSKG-IKTMIDNTLATPIFQKPLDMGIDLEVHSFTKYLGGHSDLIGGVVIGAQK 227
Query: 785 AI 790
+
Sbjct: 228 EV 229
>UniRef50_A2Z703 Cluster: Putative uncharacterized protein; n=3;
Oryza sativa|Rep: Putative uncharacterized protein -
Oryza sativa subsp. indica (Rice)
Length = 451
Score = 125 bits (301), Expect = 1e-27
Identities = 76/217 (35%), Positives = 121/217 (55%), Gaps = 13/217 (5%)
Frame = +2
Query: 152 TIAIHAGQEPEKW--NSAAVVTPIVTSTT--FKQPAP--AEHTG----FEYGRSGNPTRN 301
T+A+HAG++ + ++ TPIV+STT F+ A A G FEYGR GNPT
Sbjct: 84 TLAVHAGEKLGSGAAETDSIATPIVSSTTHWFRDSADLIAFREGWRRSFEYGRYGNPTVK 143
Query: 302 TLEECLAALDGGKYGL-TFASXXXXXXXXXXXXNHGDHIVSSDDVYGGTNRLLRQVIARL 478
LEE ++AL+ + L T + G H+V + D Y + ++++
Sbjct: 144 VLEEKISALERAEATLVTSSGMNAIVATLLALVPPGGHVVVTADCYSEARAFIHDKLSKM 203
Query: 479 GINTTFTDFTN-IEKVKNAMQEN-TKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVV 652
GI +TF D + +E +++ + E+ M + ++ TNP LKVVD+ + ++ RG +V +
Sbjct: 204 GITSTFVDLDDDMEALESVLDEDEVTMFYADSMTNPHLKVVDVARVAELCHRRG-ALVCI 262
Query: 653 DNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMG 763
D+T +P Q+PL GAD+V++S TKY+ GH DVI G
Sbjct: 263 DSTLASPINQKPLALGADVVLHSATKYIAGHHDVIAG 299
>UniRef50_A2BL10 Cluster: Methionine gamma-lyase; n=1; Hyperthermus
butylicus DSM 5456|Rep: Methionine gamma-lyase -
Hyperthermus butylicus (strain DSM 5456 / JCM 9403)
Length = 397
Score = 125 bits (301), Expect = 1e-27
Identities = 77/206 (37%), Positives = 112/206 (54%), Gaps = 10/206 (4%)
Frame = +2
Query: 197 AAVVTPIVTSTTFKQP---APA-EHTGFEYGRSGNPTRNTLEECLAALDGGKYGLTF-AS 361
A +VTPI + F P +P ++Y R NPT TLE+ + L+ G+ L F
Sbjct: 30 APIVTPIYRTAPFMFPREDSPMIRGRPYKYSREDNPTIVTLEKAITILEEGEDTLVFNTG 89
Query: 362 XXXXXXXXXXXXNHGDHIVSSDDVYGGTNRLLRQVIARLGINTTFTDFTNIEKVKNAMQE 541
GD +V++ + YG T LL++ + R G+ + + A +
Sbjct: 90 MAAISTLLFALLGPGDRVVATREAYGSTLHLLKE-LERWGVKVVLAGPDSGDIASEASKP 148
Query: 542 NTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQRPLXFGADIVMYS 721
TK++++ET TNPLL V D+ + K AR G I+VV DNTF TP L RPL GA +V++S
Sbjct: 149 GTKLVFVETITNPLLHVTDVPEVAKAARESGAILVV-DNTFATPILFRPLRHGATLVVHS 207
Query: 722 LTKYMNGHSDVIMG-----AAIVNDK 784
LTKYM GH+DV+ G A+IV+D+
Sbjct: 208 LTKYMAGHNDVMGGSVTGPASIVSDR 233
>UniRef50_Q0SFV6 Cluster: O-acetylhomoserine
aminocarboxypropyltransferase; n=1; Rhodococcus sp.
RHA1|Rep: O-acetylhomoserine
aminocarboxypropyltransferase - Rhodococcus sp. (strain
RHA1)
Length = 432
Score = 124 bits (299), Expect = 3e-27
Identities = 76/224 (33%), Positives = 110/224 (49%), Gaps = 9/224 (4%)
Frame = +2
Query: 128 LKQKPGFATIAIHAGQEPEKWNSAAVVTPIVTST-----TFKQPAPA---EHTGFEYGRS 283
+ + GFAT + G +P + A+ PI S +F+Q G Y R+
Sbjct: 1 MPETTGFATRQVRTGYQPGTPQNTAI-PPIYQSVAYDFGSFEQARDIFSLRRKGNLYSRT 59
Query: 284 GNPTRNTLEECLAALDGGKYGL-TFASXXXXXXXXXXXXNHGDHIVSSDDVYGGTNRLLR 460
GNPT+ E+ LA LD G L T + G HIV++ +YGGT LL
Sbjct: 60 GNPTQAVFEQRLADLDDGVAALATGSGQSAVAVALLTLAKSGQHIVAARQLYGGTVDLLS 119
Query: 461 QVIARLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDI 640
A GI T D +++ + A + T+ + ET NP+ V+D+ A+ IA G +
Sbjct: 120 DTFADFGIEVTLVDQDDLDAWRAAARPETRAFFAETIGNPVASVLDVRAVADIAHQAG-V 178
Query: 641 IVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAI 772
++VDNT TPYL RP FGADI +YS TK++ GH + G +
Sbjct: 179 PLIVDNTIATPYLLRPKDFGADITVYSATKFIGGHGSSLGGVIV 222
>UniRef50_A4AA77 Cluster: Cystathionine beta-lyase; n=2;
Bacteria|Rep: Cystathionine beta-lyase - Congregibacter
litoralis KT71
Length = 439
Score = 124 bits (299), Expect = 3e-27
Identities = 61/190 (32%), Positives = 101/190 (53%), Gaps = 1/190 (0%)
Frame = +2
Query: 236 KQPAPAEHTGFEYGRSGNPTRNTLEECLAALDGGKYGLTFASXXXXXXXXXX-XXNHGDH 412
++ AP + YGR G PT LE+ + LD + S + GDH
Sbjct: 87 REAAPLDREHMYYGRMGTPTTRALEDAICELDNSVGAVLATSGTASIASILNCYLSPGDH 146
Query: 413 IVSSDDVYGGTNRLLRQVIARLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKV 592
++ D VYG T + +AR G+ T+F D E +++ + ++T+MI++E+P + ++
Sbjct: 147 LLMVDSVYGPTRKFCVGSLARRGVRTSFYDPLKHESLESLIDDSTRMIFMESPGSATFEI 206
Query: 593 VDIEAIVKIARSRGDIIVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAI 772
D+ AIV +A+ G ++ +DNT+ TP L PL FG D+ M S TKY+NGH+D + G
Sbjct: 207 QDVPAIVAVAKQHG-LLTAIDNTWATPLLFNPLDFGVDLAMQSGTKYLNGHADCLFGVTT 265
Query: 773 VNDKAIGXKL 802
+ + +L
Sbjct: 266 MRSPELYTQL 275
>UniRef50_Q399B4 Cluster: Cystathionine beta-lyase; n=15;
Proteobacteria|Rep: Cystathionine beta-lyase -
Burkholderia sp. (strain 383) (Burkholderia cepacia
(strain ATCC 17760/ NCIB 9086 / R18194))
Length = 393
Score = 124 bits (298), Expect = 3e-27
Identities = 68/182 (37%), Positives = 103/182 (56%), Gaps = 1/182 (0%)
Frame = +2
Query: 260 TGFEYGRSGNPTRNTLEECLAALDGGKYGL-TFASXXXXXXXXXXXXNHGDHIVSSDDVY 436
T YGR G+PT LE+ LA L+G L T + N GDH++ +D VY
Sbjct: 49 TPLAYGRHGSPTTRALEKALARLEGAHAALLTPSGLSAITTALLAVLNPGDHLLMADSVY 108
Query: 437 GGTNRLLRQVIARLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVK 616
T + +ARLGI TT+ D T + + M+ NT+ ++ E+P + +V DI AI +
Sbjct: 109 DPTRSFCDETLARLGIETTYFDPTIGADIASLMRPNTRAVFAESPGSLTFEVQDIPAISR 168
Query: 617 IARSRGDIIVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVNDKAIGX 796
+A RG +V++DNT+ TP R G D+ +++ TKY+ GHSDV+MG AI+ +A+
Sbjct: 169 VAHQRG-AVVLLDNTWGTPLNFRSFSHGVDVSIHAATKYIAGHSDVLMG-AILTTEALAP 226
Query: 797 KL 802
K+
Sbjct: 227 KV 228
>UniRef50_A5MZ94 Cluster: O-acetyl-L-homoserine
sulfhydrylase-related protein; n=4; Bacteria|Rep:
O-acetyl-L-homoserine sulfhydrylase-related protein -
Clostridium kluyveri DSM 555
Length = 442
Score = 123 bits (297), Expect = 5e-27
Identities = 79/228 (34%), Positives = 115/228 (50%), Gaps = 10/228 (4%)
Frame = +2
Query: 131 KQKPGFATIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPAPAE--------HTGFEYGRSG 286
K+ F TI I G ++ N + V PI + F + GF Y R
Sbjct: 3 KENLRFDTIKIRGGYNSKEHNHSVSV-PIYETAAFDLGSTERAGKLFSFSELGFIYSRLS 61
Query: 287 NPTRNTLEECLAALDGGKYGLTFASXXXXXXXXXXX-XNHGDHIVSSDDVYGGTNRLLRQ 463
NPT LE+ +AALDG + +S G I+++ +YGGT ++
Sbjct: 62 NPTVEVLEKRVAALDGAAGDIALSSGMAAITYTLLNVAEDGGRILTTPYLYGGTLDGFKK 121
Query: 464 VIARLGINTT-FTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDI 640
+ + GI F DF N E + ++ +TK I++E+ +NP V DIE I K+A DI
Sbjct: 122 LYPKFGIKIDKFEDFNNPEALAKQIKPDTKAIFVESISNPNAAVADIEKIAKVAHEY-DI 180
Query: 641 IVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVNDK 784
++VDNT TPYL P+ +GADIV+YS TK +NGH +VI G + + K
Sbjct: 181 PLIVDNTLATPYLLNPIKYGADIVIYSATKALNGHGNVIAGIILESGK 228
>UniRef50_Q6AJ03 Cluster: Probable cystathionine beta-lyase; n=1;
Desulfotalea psychrophila|Rep: Probable cystathionine
beta-lyase - Desulfotalea psychrophila
Length = 386
Score = 123 bits (296), Expect = 6e-27
Identities = 61/178 (34%), Positives = 100/178 (56%), Gaps = 1/178 (0%)
Frame = +2
Query: 254 EHTGFEYGRSGNPTRNTLEECLAALDGGKYGLTFASXXXXXXXXXXXXNH-GDHIVSSDD 430
++ G YG P + EE L L+GG+ F S GDHIV D+
Sbjct: 50 KYPGLTYGTDRLPAQRAFEEALCQLEGGEICRAFQSGINAIVHTLQAFTKAGDHIVVCDN 109
Query: 431 VYGGTNRLLRQVIARLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAI 610
VY T+ +V+++ G+ ++ + + +++NT +I++E+P + ++ DIEAI
Sbjct: 110 VYWPTSNFCNKVLSKFGVEISYAPSAVGADIADYLRDNTSLIFMESPGSNTFEIQDIEAI 169
Query: 611 VKIARSRGDIIVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVNDK 784
+IAR+R DI+ ++D T+ TP R L FG D+ + S TKY++GHSD+++G A VN K
Sbjct: 170 TQIARAR-DIVTILDGTWGTPLYHRALSFGVDVSIQSATKYISGHSDILLGTATVNHK 226
>UniRef50_Q6W1U5 Cluster: Cystathionine gamma-synthase; n=2;
Proteobacteria|Rep: Cystathionine gamma-synthase -
Rhizobium sp. (strain NGR234)
Length = 425
Score = 123 bits (296), Expect = 6e-27
Identities = 61/167 (36%), Positives = 93/167 (55%), Gaps = 1/167 (0%)
Frame = +2
Query: 266 FEYGRSGNPTRNTLEECLAALDGGKYGLTFASXXXXXXXXXXX-XNHGDHIVSSDDVYGG 442
F Y R NPT LE +AAL+G L A+ GDH++ SD Y G
Sbjct: 82 FLYARWTNPTVRQLELRMAALEGADDALATATGVAAIAATFLTCLKRGDHLIISDVCYAG 141
Query: 443 TNRLLRQVIARLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIA 622
N L R+++ GI T + + +++V A + NT+++ E+P NP+L++ D+ A+ +A
Sbjct: 142 ANELARRMLPDYGIEVTAVNMSRLDEVAAAFRPNTRLVHCESPCNPILRLTDLSAVAALA 201
Query: 623 RSRGDIIVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMG 763
G +V VD+T TP RPL G D+V++SLTK++NGH D + G
Sbjct: 202 HRHG-ALVSVDSTLATPVATRPLALGVDLVIHSLTKFINGHGDALGG 247
>UniRef50_Q31RB7 Cluster: O-acetylhomoserine/O-acetylserine
sulfhydrylase; n=3; cellular organisms|Rep:
O-acetylhomoserine/O-acetylserine sulfhydrylase -
Synechococcus sp. (strain PCC 7942) (Anacystis nidulans
R2)
Length = 434
Score = 122 bits (295), Expect = 8e-27
Identities = 80/217 (36%), Positives = 111/217 (51%), Gaps = 10/217 (4%)
Frame = +2
Query: 152 TIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPAPAEHT---------GFEYGRSGNPTRNT 304
T+A+HAGQ+P+ + V PI +T++ AEH G Y R NPT +
Sbjct: 7 TLALHAGQKPDPTTGSRAV-PIYQTTSYVFE-DAEHAANLFALKAFGNIYTRLMNPTTDV 64
Query: 305 LEECLAALDGGKYGL-TFASXXXXXXXXXXXXNHGDHIVSSDDVYGGTNRLLRQVIARLG 481
LE+ LAAL GG + T + + G +I+S+ ++YGGT L R + R G
Sbjct: 65 LEQRLAALHGGTGAVATSSGQAAIFYAIAAITSAGQNIISTTNLYGGTINLFRHTLKRFG 124
Query: 482 INTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNT 661
I F D ++ V A+ ENT++++ E+ NP V D EAI IA G I +VDNT
Sbjct: 125 IEVRFVDSSDASSVAAAIDENTRLVYTESIGNPKGNVDDFEAIAAIAHDSG-IPFIVDNT 183
Query: 662 FLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAI 772
P L PL GAD+V+ SLTK GH + G I
Sbjct: 184 VSPPPLFNPLEHGADVVVLSLTKLAGGHGTSLGGIVI 220
>UniRef50_Q2S2T9 Cluster: Cystathionine beta-lyase MetC; n=1;
Salinibacter ruber DSM 13855|Rep: Cystathionine
beta-lyase MetC - Salinibacter ruber (strain DSM 13855)
Length = 382
Score = 122 bits (295), Expect = 8e-27
Identities = 76/206 (36%), Positives = 103/206 (50%), Gaps = 2/206 (0%)
Frame = +2
Query: 152 TIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPAPAEHTGFEYGRSGN-PTRNTLEECLAAL 328
T +IHAG EPE AV P+ + T+ P Y R N P L E LAAL
Sbjct: 6 TQSIHAG-EPEPRIEGAVSMPVFQTATYTHDDPGASP--RYVRYNNSPNHQALHEKLAAL 62
Query: 329 DGGKYGLTFASXXXXXXXXXXXX-NHGDHIVSSDDVYGGTNRLLRQVIARLGINTTFTDF 505
+ L AS GDH+V+ +YGGT LL ++ R GI T
Sbjct: 63 TETERALVTASGMAAISSALLGVLEAGDHLVAPHSLYGGTLALLNDLLPRFGITHTLVPE 122
Query: 506 TNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQR 685
E A+Q NTK+++ E TNP L+V+++ +V +A D+ V+DNTF +P R
Sbjct: 123 DTPEAWTAALQPNTKVLYAEAITNPRLEVLNLTGMVDLAEEH-DLTTVIDNTFASPVNLR 181
Query: 686 PLXFGADIVMYSLTKYMNGHSDVIMG 763
P G D+V++S TKY+ GHSDV G
Sbjct: 182 PASLGFDVVLHSATKYLGGHSDVAAG 207
>UniRef50_Q11FS5 Cluster: Cystathionine beta-lyase; n=5;
Alphaproteobacteria|Rep: Cystathionine beta-lyase -
Mesorhizobium sp. (strain BNC1)
Length = 398
Score = 122 bits (295), Expect = 8e-27
Identities = 65/206 (31%), Positives = 108/206 (52%), Gaps = 1/206 (0%)
Frame = +2
Query: 188 WNSAAVVTPIVTSTTFKQPAPAEHTGFEYGRSGNPTRNTLEECLAALDGGKYGL-TFASX 364
W ++ +V P + + + H + YG G PT TLE +A L+GG + T +
Sbjct: 37 WRASTIVFPDMAAYAARNSKG--HDAYSYGLHGTPTTRTLEAQIARLEGGGRSIVTSSGL 94
Query: 365 XXXXXXXXXXXNHGDHIVSSDDVYGGTNRLLRQVIARLGINTTFTDFTNIEKVKNAMQEN 544
+ GD ++ D VY + + R+G++ + D + +
Sbjct: 95 SAITMTLQTMLSPGDTVLLVDTVYPPVREFADRFLRRMGVDIVYYDPAIGAGIAELITAT 154
Query: 545 TKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQRPLXFGADIVMYSL 724
T+++W+E+P + ++V DI AIV AR+RG + +DNT+ TP L +PL G DIV+ ++
Sbjct: 155 TRLVWMESPGSTTMEVQDIPAIVAAARARG-VPTAIDNTWATPLLLKPLELGVDIVIQAV 213
Query: 725 TKYMNGHSDVIMGAAIVNDKAIGXKL 802
+KYM GHSD++MGA V D A+ +L
Sbjct: 214 SKYMAGHSDLLMGAVTVRDLALFDRL 239
>UniRef50_A4CKV8 Cluster: Cystathionine beta-lyase; n=11;
Bacteroidetes|Rep: Cystathionine beta-lyase -
Robiginitalea biformata HTCC2501
Length = 417
Score = 122 bits (295), Expect = 8e-27
Identities = 68/166 (40%), Positives = 97/166 (58%), Gaps = 1/166 (0%)
Frame = +2
Query: 272 YGRSGNPTRNTLEECLAALDGGKYG-LTFASXXXXXXXXXXXXNHGDHIVSSDDVYGGTN 448
Y R +P+ L E LAAL+G + +T + + GDH+VSS +YGGT
Sbjct: 64 YSRHSSPSNLYLGEALAALEGTESANVTASGMGAITAVILQLCSSGDHLVSSRTIYGGTY 123
Query: 449 RLLRQVIARLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARS 628
L+ + R I +F D T+ E V A+ + T+MI+ E+ +NPLL+V DI + K+A
Sbjct: 124 AFLKNFLKRFDIAVSFVDITDPEAVAAAITDKTRMIYCESVSNPLLEVADIPTLAKLAND 183
Query: 629 RGDIIVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGA 766
RG I +VVDNTF +P P GA IV++SLTK++NG SD + GA
Sbjct: 184 RG-IRLVVDNTF-SPLSLSPARLGAHIVVHSLTKFINGSSDAVAGA 227
>UniRef50_Q5K6Y9 Cluster: Cystathionine gamma-lyase, putative; n=1;
Filobasidiella neoformans|Rep: Cystathionine
gamma-lyase, putative - Cryptococcus neoformans
(Filobasidiella neoformans)
Length = 466
Score = 122 bits (295), Expect = 8e-27
Identities = 83/244 (34%), Positives = 125/244 (51%), Gaps = 33/244 (13%)
Frame = +2
Query: 146 FATIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPAPAEHTGFEYGRSGNPTRNTLEECLAA 325
FAT AIH G EP+ ++ AVV + +TTFKQ + GF+Y RSGNPTR++LE+ L +
Sbjct: 6 FATRAIHIGSEPDP-STGAVVPSLSVATTFKQDGINKTRGFDYSRSGNPTRSSLEQLLTS 64
Query: 326 L------DGGKYGLTFASXXXXXXXXXX---------------XXNHGDHIVSSDDVYGG 442
L D F+S G HI++ +DVYGG
Sbjct: 65 LETAPLSDAQGESFVFSSGSAATAAIAHWVTLTKKEGGAGGADGNGGGGHILAVNDVYGG 124
Query: 443 TNRLLRQVIARLGINTTFTDFTNI--EKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVK 616
T R +V G++ T+ D E ++ A++ +T+++W+E PTNP L V + I
Sbjct: 125 TARYFSRVARPTGLDITYLDMIEAGEEGIRAAIRPDTRLVWLEIPTNPTLLVHPLPLISS 184
Query: 617 IARSRGD---IIVVVDNTFLTPYLQRPLXFG-------ADIVMYSLTKYMNGHSDVIMGA 766
I +S + +++VD TFL+ + PL ADI SL+KY +GHSD+I+G+
Sbjct: 185 IVKSLPEEHRPLILVDTTFLSSFNFTPLVGANPESTPLADIAYSSLSKYSSGHSDIILGS 244
Query: 767 AIVN 778
V+
Sbjct: 245 VTVS 248
>UniRef50_Q97MT9 Cluster: O-acetylhomoserine sulfhydrylase; n=4;
Clostridiales|Rep: O-acetylhomoserine sulfhydrylase -
Clostridium acetobutylicum
Length = 409
Score = 122 bits (294), Expect = 1e-26
Identities = 71/218 (32%), Positives = 115/218 (52%), Gaps = 9/218 (4%)
Frame = +2
Query: 146 FATIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPAPAE--------HTGFEYGRSGNPTRN 301
F+T IH E N+ A PI S + +P E G+ Y R NPT
Sbjct: 3 FSTKLIHGNYNLE--NTGATNVPIYMSNAYAHSSPQELENVFKGKFPGYVYSRFSNPTVL 60
Query: 302 TLEECLAALDGGKYGLTFASXXXXXXXXXXXXNH-GDHIVSSDDVYGGTNRLLRQVIARL 478
E +A+++GG + AS H GD I++S +YGGT L+ + +
Sbjct: 61 EFERRMASIEGGLTATSAASGMSAIYMAITNIVHPGDEIIASTGLYGGTYTLISN-LQNI 119
Query: 479 GINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDN 658
G+ F + + + + N + ENTK+++ ET NP L ++DIE++ ++ + +G II +VD+
Sbjct: 120 GVKVIFLEDISKKTLLNNINENTKLVYTETIGNPKLDILDIESVGRVCKEKG-IIFMVDS 178
Query: 659 TFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAI 772
T TPYL P +GAD++++S +KY+NG S+ I G +
Sbjct: 179 TISTPYLINPSKYGADVIIHSTSKYINGTSNAIGGMIV 216
>UniRef50_A0L907 Cluster: Cystathionine gamma-synthase; n=1;
Magnetococcus sp. MC-1|Rep: Cystathionine gamma-synthase
- Magnetococcus sp. (strain MC-1)
Length = 396
Score = 122 bits (294), Expect = 1e-26
Identities = 73/224 (32%), Positives = 113/224 (50%), Gaps = 7/224 (3%)
Frame = +2
Query: 131 KQKPGFATIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPAPA------EHTGFEYGRSGNP 292
K + G T A+HAG ++ + +S F A E G Y R NP
Sbjct: 5 KTRYGKNTRALHAGLHASDARENSLAMHVTSSFFFNSAGQAAAVFGDEEEGNIYSRFSNP 64
Query: 293 TRNTLEECLAALDGGKYGLTFASXXXXXXXXXXXX-NHGDHIVSSDDVYGGTNRLLRQVI 469
T E+ LA L+ G+ + AS GDH++ S V+G T + + +
Sbjct: 65 TVEAFEQRLAELEEGEACVATASGMAAIFGVFMQLLQQGDHLILSRSVFGSTINVAKNYL 124
Query: 470 ARLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVV 649
+ GI F +++ + A++ NTKM ++E+P NP L++ D+ A+ ++A+ G I +V
Sbjct: 125 TKFGIQIDFVGLADMDGWRRAIRPNTKMFYLESPANPTLEMADLAALGQLAKEHG-IKMV 183
Query: 650 VDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVND 781
VDN F TP LQ PL GA +V++S TKY++G V +G IV D
Sbjct: 184 VDNVFCTPILQNPLNLGAHLVVHSATKYLDGQGRV-LGGGIVGD 226
>UniRef50_Q5UZ20 Cluster: O-acetylhomoserine (Thiol)-lyase; n=10;
cellular organisms|Rep: O-acetylhomoserine (Thiol)-lyase
- Haloarcula marismortui (Halobacterium marismortui)
Length = 432
Score = 122 bits (293), Expect = 1e-26
Identities = 77/222 (34%), Positives = 106/222 (47%), Gaps = 9/222 (4%)
Frame = +2
Query: 134 QKPGFATIAIHAGQEPEKWNSAAVVTPI--VTSTTFKQPAPA------EHTGFEYGRSGN 289
Q GF T A+H GQE + + P+ TS F+ A E G Y R N
Sbjct: 5 QDHGFETDALHVGQEEPDAEARSRAPPLYQTTSYVFEDAEDAAKQFALEKPGHIYSRLMN 64
Query: 290 PTRNTLEECLAALDGGKYGLTFASXXXXXXXXXXX-XNHGDHIVSSDDVYGGTNRLLRQV 466
PT L+E LAAL+GG + AS + GD++V++ +YGGT
Sbjct: 65 PTVGMLQERLAALEGGVGAVATASGMASLNLATFLLADVGDNVVTASSLYGGTYTYYTHT 124
Query: 467 IARLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIV 646
R G+ T F D + + A+ ENT + ET NP L D E + +IA G +
Sbjct: 125 APRNGVETRFVDTLDYDAYAEAIDENTAYVHCETIGNPSLVTPDFERLAEIAHDHG-VPF 183
Query: 647 VVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAI 772
VDNTF TPYL P+ GAD+V S TK+++GH + G +
Sbjct: 184 FVDNTFATPYLCNPIEHGADLVWNSTTKWIHGHGTTVGGVLV 225
>UniRef50_Q7VIG9 Cluster: O-acetylhomoserine (Thiol)-lyase MetY;
n=18; Epsilonproteobacteria|Rep: O-acetylhomoserine
(Thiol)-lyase MetY - Helicobacter hepaticus
Length = 430
Score = 121 bits (292), Expect = 2e-26
Identities = 76/217 (35%), Positives = 113/217 (52%), Gaps = 10/217 (4%)
Frame = +2
Query: 152 TIAIHAGQEPEKWNSAAVVTPIVTSTTFK----QPAPA----EHTGFEYGRSGNPTRNTL 307
T+A+HAG + + +V PI +T + + A A + G Y R NPT + L
Sbjct: 13 TLALHAGYTYDTQRTISV--PIYQNTAYSFESLEQAAARFGLQEIGNIYTRLSNPTTDVL 70
Query: 308 EECLAALDGGKYGLTFASXXXXXXXXXXX-XNHGDHIVSSDDVYGGTNRLLRQVIARLGI 484
LAA++GG +G+ AS GD+IV S+ +YGGT L + R GI
Sbjct: 71 GARLAAVEGGIFGVPTASGSAAIFYAIVNCAQSGDNIVFSNKIYGGTQTLFVHTLKRFGI 130
Query: 485 NTTFTDFTNIEK-VKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNT 661
T D NIE +++ + + TK I+ E+ +NP + + D E I IA+ II + DNT
Sbjct: 131 QTKVFDIDNIESSLESVIDDKTKAIFFESISNPQISIADTEKITAIAKKH-KIISICDNT 189
Query: 662 FLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAI 772
T +L +P +G DI +YSL+KY+NG + GA I
Sbjct: 190 IPTAFLHKPFDYGVDISIYSLSKYINGQGSALGGAII 226
>UniRef50_Q1ITX7 Cluster: Cystathionine gamma-lyase; n=1;
Acidobacteria bacterium Ellin345|Rep: Cystathionine
gamma-lyase - Acidobacteria bacterium (strain Ellin345)
Length = 459
Score = 121 bits (292), Expect = 2e-26
Identities = 82/246 (33%), Positives = 123/246 (50%), Gaps = 27/246 (10%)
Frame = +2
Query: 134 QKPGFATIAIHAGQEPEKWN-SAAVVTPIVTSTTFKQPAPAEHTG--FE----------- 271
QK T IH KW+ S VV P+ +S TF+ + FE
Sbjct: 24 QKYDLRTRLIHGSMRTPKWDYSHHVVPPLTSSATFRLSSSQRGARGFFEFACDTIDTTRQ 83
Query: 272 -----YGRSGNPTRNTLEECLAALDGGKYGLTFASXXXXXXXXXXXXNH-GDHIVSSDDV 433
Y R PTR LEE LAA + G+ G+ FA+ GD +V+ + +
Sbjct: 84 VPIYIYDRLDEPTRGMLEENLAAAEAGEMGVCFATGMAAISASICALTRAGDQVVAHNTL 143
Query: 434 YGGTNRLLRQVIARLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIV 613
YG T L+ + R G+ T F D N +++ A+ +T++++ ETP NP L+++DI A+
Sbjct: 144 YGCTYSLMTNWLPRQGVATRFVDMRNPKEIAKAINAHTRIVYFETPVNPNLELIDIAAVR 203
Query: 614 KIA----RSRGD---IIVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAI 772
+I + R + I VVVDNTF TP+ QRPL GA +V++SLTK + G MG +
Sbjct: 204 EIVDHANKGRSELEQIRVVVDNTFATPFCQRPLTLGAHMVVHSLTKGIGGFG-TDMGGVV 262
Query: 773 VNDKAI 790
+ K++
Sbjct: 263 IGPKSL 268
>UniRef50_A3UCA9 Cluster: Cystathionine gamma-synthase; n=2;
Hyphomonadaceae|Rep: Cystathionine gamma-synthase -
Oceanicaulis alexandrii HTCC2633
Length = 378
Score = 120 bits (290), Expect = 3e-26
Identities = 71/212 (33%), Positives = 111/212 (52%), Gaps = 2/212 (0%)
Frame = +2
Query: 152 TIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPAPAEHTG-FEYGRSGNPTRNTLEECLAAL 328
T+A A + ++ + AV+ P+ +TTF + G +Y R PT + LAAL
Sbjct: 7 TLAAQALHQTDR-ETGAVIPPVHPATTFMRDQKNALVGEMDYRRPQGPTEVQAAKVLAAL 65
Query: 329 DGGKYGLTFASXXXXXXXXXXXXNHGDHIVSSDDVYGGTNRLLRQVIARLGINTTFTDFT 508
+ F+S G H+V+ ++Y G +LL + ++ I+ +F +
Sbjct: 66 ENAADARLFSSGLAAISAVLDTLEVGAHVVAQTEMYYGAKKLLHHLASKGLISLSFFEPH 125
Query: 509 NIEKVKNAMQEN-TKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQR 685
+I +K A+Q T+++WIETP NP +VDI +IA G ++ V D+T P R
Sbjct: 126 DINGLKKAVQGGRTELVWIETPANPSWAIVDIARAAEIAHEAGAMLGV-DSTCAPPCTTR 184
Query: 686 PLXFGADIVMYSLTKYMNGHSDVIMGAAIVND 781
L GAD+VM+S TKY+NGHSDV+MGA +
Sbjct: 185 ALDLGADLVMHSATKYLNGHSDVLMGAVATKE 216
>UniRef50_A3JID5 Cluster: Cystathionine beta-lyase; n=3;
Marinobacter|Rep: Cystathionine beta-lyase -
Marinobacter sp. ELB17
Length = 397
Score = 120 bits (290), Expect = 3e-26
Identities = 75/205 (36%), Positives = 108/205 (52%), Gaps = 4/205 (1%)
Frame = +2
Query: 164 HAGQEPEKWNSAAVVTPIVTSTTFKQPA--PAEHTGFEYGRSG-NPTRNTLEECLAALDG 334
H Q+ ++ T TT +Q A EH G Y R G NPT LE+ LA L+
Sbjct: 22 HRDQQGSPYSPVYNTTTYRFDTTAEQLAVVKGEHDGNLYTRWGTNPTIKELEQGLAQLES 81
Query: 335 GKYGLTFASXXXXXXXXXXXXNHGDH-IVSSDDVYGGTNRLLRQVIARLGINTTFTDFTN 511
+ GL FAS HG + IV D+YGGT LL LGI F
Sbjct: 82 AQAGLAFASGMAAISATLFA--HGRNGIVCVGDLYGGTQELLMNHFEPLGIPFIFLLNQQ 139
Query: 512 IEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQRPL 691
+++++ + + +++ ETP NP + ++DI + + A ++G ++ VDNTF +P QRPL
Sbjct: 140 LDELEQHLTKPGMLVYCETPANPTMAILDIADLARRAHAKG-ALMAVDNTFASPINQRPL 198
Query: 692 XFGADIVMYSLTKYMNGHSDVIMGA 766
GAD+VM+S TKY+ GHSD+ GA
Sbjct: 199 ELGADLVMHSATKYLAGHSDLTAGA 223
>UniRef50_UPI0000E47CE2 Cluster: PREDICTED: similar to cystathionine
beta-lyase; n=2; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to cystathionine beta-lyase -
Strongylocentrotus purpuratus
Length = 392
Score = 120 bits (289), Expect = 4e-26
Identities = 59/174 (33%), Positives = 94/174 (54%), Gaps = 1/174 (0%)
Frame = +2
Query: 263 GFEYGRSGNPTRNTLEECLAALDGGKYGLTFASXXXXXXXXXXXX-NHGDHIVSSDDVYG 439
G+ YGR N + + + + ++GG + S GDHI++ D VY
Sbjct: 87 GYVYGRCNNHSCDVVAHAVNKIEGGVGACVYPSGMSAISNNILAVVKTGDHIIAPDPVYS 146
Query: 440 GTNRLLRQVIARLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKI 619
G L+ VI G+ TF +++ + A++ NTK+ + ETPTNP++ ++D++A +
Sbjct: 147 GVYAFLKHVIGNYGVEVTFVPSGDLDAYRKAIKPNTKVFYGETPTNPVMSLLDLKAFADL 206
Query: 620 ARSRGDIIVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVND 781
A+S I + D+TF +P LQ L G DIV S TKYM GHSD++ G+ +D
Sbjct: 207 AKSVPGAISMCDSTFASPILQDTLGLGIDIVFQSCTKYMGGHSDLMGGSMCTSD 260
>UniRef50_Q9RSD8 Cluster: O-acetylhomoserine
(Thiol)-lyase/O-acetylserine (Thiol)-lyase; n=2;
Deinococcus|Rep: O-acetylhomoserine
(Thiol)-lyase/O-acetylserine (Thiol)-lyase - Deinococcus
radiodurans
Length = 418
Score = 120 bits (289), Expect = 4e-26
Identities = 63/172 (36%), Positives = 93/172 (54%), Gaps = 1/172 (0%)
Frame = +2
Query: 263 GFEYGRSGNPTRNTLEECLAALDGGKYGLTFASXXXXXXXXXXXX-NHGDHIVSSDDVYG 439
G Y R NPT LEE L L+GG + AS GDH+VSS ++G
Sbjct: 59 GLSYARIQNPTVRALEERLTVLEGGAATVALASGQAASLTAILSVCRAGDHVVSSASLFG 118
Query: 440 GTNRLLRQVIARLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKI 619
G+ +L ++ +GI T + + E+++ AMQ+NT+++W E +NP V D+EA+ +
Sbjct: 119 GSTGMLTNILPLMGITATLVE-GHPEQIRAAMQDNTRLVWAEMISNPSGAVADVEALAGV 177
Query: 620 ARSRGDIIVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIV 775
A RG ++ + + YL RPL GADIV SLTK+ GH V+ G+ V
Sbjct: 178 AHERGALLAIDNTCGGVGYLCRPLDHGADIVSQSLTKWAGGHGSVMGGSVTV 229
>UniRef50_A6UGP2 Cluster: Cystathionine gamma-synthase; n=1;
Sinorhizobium medicae WSM419|Rep: Cystathionine
gamma-synthase - Sinorhizobium medicae WSM419
Length = 400
Score = 120 bits (288), Expect = 6e-26
Identities = 61/165 (36%), Positives = 91/165 (55%), Gaps = 1/165 (0%)
Frame = +2
Query: 272 YGRSGNPTRNTLEECLAALDGGKYGLTFASXXXXXXXXXXXX-NHGDHIVSSDDVYGGTN 448
Y R GNPT EE +A L GG L AS GDHIV+ Y T+
Sbjct: 55 YSRCGNPTEYKFEEHIAKLTGGTACLATASGMAAISHALFGILKAGDHIVADLTTYSSTH 114
Query: 449 RLLRQVIARLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARS 628
G+ + D T++ V+NA+ E TK++++E NP +KV ++A+V++A +
Sbjct: 115 EFFDHRAQDFGLKVSLVDCTDVRAVENALTEETKVLYVEAIANPTMKVPPLKALVELAHA 174
Query: 629 RGDIIVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMG 763
RG I+V+ DNTF +P + RP FG D+V+ S TK++ GH+D + G
Sbjct: 175 RG-IVVICDNTFASPAVCRPHDFGVDVVVESATKFIGGHNDAVGG 218
>UniRef50_A6GHC8 Cluster: Cystathionine gamma-synthase; n=1;
Plesiocystis pacifica SIR-1|Rep: Cystathionine
gamma-synthase - Plesiocystis pacifica SIR-1
Length = 369
Score = 120 bits (288), Expect = 6e-26
Identities = 66/175 (37%), Positives = 97/175 (55%), Gaps = 7/175 (4%)
Frame = +2
Query: 269 EYGRSGNPTRNTLEECLAAL-----DGGKYG--LTFASXXXXXXXXXXXXNHGDHIVSSD 427
EYGR GNPT E LAAL DGG G L + G H++ +
Sbjct: 28 EYGRYGNPTVAATEAKLAALEAGEADGGGCGAVLMASGMAAITTTLLAMLRAGQHVIFTA 87
Query: 428 DVYGGTNRLLRQVIARLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEA 607
DVY T R +A+ G+ T +E ++ A+++ T++I+ E PTNP L+VVD+E
Sbjct: 88 DVYRKTRLFARSYLAKFGVEFDIVAPT-LEAIEGAVRDTTRIIFTEAPTNPYLRVVDLEG 146
Query: 608 IVKIARSRGDIIVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAI 772
+V +A++R I ++D TF TP RPL G D+V++S TKY+ GH+D++ G I
Sbjct: 147 VVALAKARR-IKTIIDATFATPINMRPLSLGVDLVIHSTTKYLGGHNDLLGGVVI 200
>UniRef50_A0V4A3 Cluster: O-acetylhomoserine/O-acetylserine
sulfhydrylase; n=3; Proteobacteria|Rep:
O-acetylhomoserine/O-acetylserine sulfhydrylase -
Delftia acidovorans SPH-1
Length = 475
Score = 119 bits (287), Expect = 7e-26
Identities = 72/217 (33%), Positives = 115/217 (52%), Gaps = 10/217 (4%)
Frame = +2
Query: 152 TIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPAPAEH---------TGFEYGRSGNPTRNT 304
T A+HAG + +A V PI ST+F + A+H G Y R+ NPT
Sbjct: 24 TQALHAGYRGREQQRSAAV-PIYQSTSFVFDS-AQHGANLFGLVEEGDVYSRTANPTLAV 81
Query: 305 LEECLAALDGGKYGLTFASXXXXXXXXXXX-XNHGDHIVSSDDVYGGTNRLLRQVIARLG 481
LE+ +AAL+GG L AS + GDH+V + +YGGT+ + V+A G
Sbjct: 82 LEQRIAALEGGVAALALASGMAAIDVALATLASAGDHVVVASQLYGGTHNFIAHVLASRG 141
Query: 482 INTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNT 661
+ +T + + ++ A+ TK +++E+ NP + D+ + I+ + G + +VVDNT
Sbjct: 142 VQSTAVAKDDFQALRRAIGPRTKAVFVESVGNPSGGIADLRQLADISHAAG-VALVVDNT 200
Query: 662 FLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAI 772
+P L RP +GADIV++S TK + GH +V+ G +
Sbjct: 201 VASPLLLRPFDWGADIVVHSATKAIGGHGNVLGGLIV 237
>UniRef50_Q9V088 Cluster: MetB cystathionine gamma-synthase (EC
4.2.99.9) (CGS) (O- succinylhomoserine (Thiol)-lyase);
n=9; Archaea|Rep: MetB cystathionine gamma-synthase (EC
4.2.99.9) (CGS) (O- succinylhomoserine (Thiol)-lyase) -
Pyrococcus abyssi
Length = 393
Score = 119 bits (287), Expect = 7e-26
Identities = 71/194 (36%), Positives = 104/194 (53%), Gaps = 5/194 (2%)
Frame = +2
Query: 212 PIVTSTTFKQPAPA----EHTGFEYGRSGNPTRNTLEECLAALDGGKYGLTFASXXXXXX 379
P+ + FKQ A T +Y R NPT LE+ LA L+G L F S
Sbjct: 33 PLYITAVFKQVGDAYPTDRGTELKYSREENPTVRKLEDKLAELEGSDNALAFNSGMSAIS 92
Query: 380 XXXXXX-NHGDHIVSSDDVYGGTNRLLRQVIARLGINTTFTDFTNIEKVKNAMQENTKMI 556
GD +V S + YG T L + ++ + G++ + + + + + E TK++
Sbjct: 93 TLYFSLLEGGDKVVLSMEGYGTTIELAK-LLRKFGVDVKLA-YPSADSLIETIDEETKLV 150
Query: 557 WIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQRPLXFGADIVMYSLTKYM 736
+ET TNP LKV+D+ + K R G I+VV DNTF+TP L +PL GA V++SLTKY+
Sbjct: 151 LVETMTNPTLKVIDVPEVAKRCREVGAILVV-DNTFVTPLLYKPLEDGASYVVHSLTKYI 209
Query: 737 NGHSDVIMGAAIVN 778
GH+DV+ GA + N
Sbjct: 210 AGHNDVLGGAVLWN 223
>UniRef50_Q89VE2 Cluster: O-succinylhomoserine sulfhydrylase; n=72;
cellular organisms|Rep: O-succinylhomoserine
sulfhydrylase - Bradyrhizobium japonicum
Length = 417
Score = 119 bits (286), Expect = 1e-25
Identities = 62/184 (33%), Positives = 101/184 (54%), Gaps = 1/184 (0%)
Frame = +2
Query: 254 EHTGFEYGRSGNPTRNTLEECLAALDGGKYGLTFASXXXXXXXXXXX-XNHGDHIVSSDD 430
E GF Y R NPT + E + L+G + + A+ GDH+V+S
Sbjct: 74 EDPGFIYSRYSNPTISMFERRMIELEGAEAARSAATGMAAVTTAILAPLKTGDHVVASRA 133
Query: 431 VYGGTNRLLRQVIARLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAI 610
++G +++ ++ R GI TT D ++++ + A++ NTK ++E+PTNP L V+DI I
Sbjct: 134 LFGSCLYVIQDLLPRYGIETTLVDGLDLDQWQRALRPNTKTFFLESPTNPTLDVLDIPGI 193
Query: 611 VKIARSRGDIIVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVNDKAI 790
+IA +G +VVDN F TP Q PL GAD+V+YS TK+++G + G + ++ +
Sbjct: 194 AEIAH-KGGARLVVDNVFATPIWQSPLALGADVVVYSATKHIDGQGRCLGGIILSSEAFV 252
Query: 791 GXKL 802
L
Sbjct: 253 AEHL 256
>UniRef50_Q895W3 Cluster: O-acetylhomoserine sulfhydrylase; n=40;
Bacteria|Rep: O-acetylhomoserine sulfhydrylase -
Clostridium tetani
Length = 462
Score = 119 bits (286), Expect = 1e-25
Identities = 76/226 (33%), Positives = 111/226 (49%), Gaps = 10/226 (4%)
Frame = +2
Query: 125 FLKQKPGFATIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPAPAE--------HTGFEYGR 280
F+ G TI I G P+ V PI STT+K P G Y R
Sbjct: 37 FMNNSWGKGTICIQGGYNPKPGEPR--VLPIFQSTTYKYEDPDHVAKLFDLTEEGHIYSR 94
Query: 281 SGNPTRNTLEECLAALDGGKYGLTFASXXXXXXXXXXXX-NHGDHIVSSDDVYGGTNRLL 457
NPT + EE + L+GG L +S GDHI+S+ +YGGT LL
Sbjct: 95 ISNPTVSAYEEKVNCLEGGAGALAVSSGQSATTLALLNICKSGDHIISASTIYGGTFTLL 154
Query: 458 RQVIARLGINTTFTD-FTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRG 634
+ + GI +F + ++ E + + NTK I+ ET NP L ++D + IA+ +
Sbjct: 155 SSTLKKFGIEVSFINPDSSKEDILKEFKSNTKAIFAETIGNPGLNILDFDKFSDIAQ-KT 213
Query: 635 DIIVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAI 772
++ +VDNT +PYL PL GA+IV++S TKY++GH+ I G +
Sbjct: 214 EVPFIVDNTLASPYLCSPLELGANIVIHSSTKYIDGHATSIGGIIV 259
>UniRef50_A0LY60 Cluster: O-succinylhomoserine sulfhydrylase; n=13;
Bacteria|Rep: O-succinylhomoserine sulfhydrylase -
Gramella forsetii (strain KT0803)
Length = 404
Score = 117 bits (282), Expect = 3e-25
Identities = 56/174 (32%), Positives = 101/174 (58%), Gaps = 1/174 (0%)
Frame = +2
Query: 272 YGRSGNPTRNTLEECLAALDGGKYGLTFASXXXXXXXXXXXX-NHGDHIVSSDDVYGGTN 448
Y R NP + E +A ++G + G FA+ N GDHIVS+ V+G T+
Sbjct: 70 YSRFTNPNTSEFVEKIARMEGAETGYAFATGMAAVFSTLAALLNSGDHIVSARSVFGSTH 129
Query: 449 RLLRQVIARLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARS 628
L + + I+ ++ D E +++ ++ TK+++ E+PTNP + ++D+E + +IA+
Sbjct: 130 GLFTRYFPKWNISHSYFDVNKPETIEDLIKPETKILFAESPTNPGVDILDLEFLGQIAK- 188
Query: 629 RGDIIVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVNDKAI 790
+ +I+++DN F TPY+Q P+ FGAD+V++S TK ++G V+ G + + I
Sbjct: 189 KHHLILIIDNCFATPYIQNPIKFGADLVIHSATKLIDGQGRVLGGVTVGREDLI 242
>UniRef50_A5V1Q1 Cluster: Cystathionine gamma-synthase; n=2;
Roseiflexus|Rep: Cystathionine gamma-synthase -
Roseiflexus sp. RS-1
Length = 409
Score = 116 bits (280), Expect = 5e-25
Identities = 74/223 (33%), Positives = 111/223 (49%), Gaps = 16/223 (7%)
Frame = +2
Query: 152 TIAIHAGQEPEKWNSAAVVTPIVTSTTFKQP-------APAEHTGFEYGRSGNPTRNTLE 310
T +HAG+ S TPI TS T+ P A +G+ Y R GNPT LE
Sbjct: 12 TRLVHAGERAPAPGSTPTATPIYTSATYLHPDLAALDTALESGSGYVYTRYGNPTVAALE 71
Query: 311 ECLAALDGGKYGLTFASXXXXXXXXXXXXN--HGDH------IVSSDDVYGGTNRLLRQV 466
E + ++ G FAS G I+++ D+YG T LL++
Sbjct: 72 EAMTVVERGAGATAFASGMAALYAALLAAGTPRGATAPAPRAILAARDMYGATTLLLQEF 131
Query: 467 IARLGINTTFTDFTNIEKVKNAMQENTK-MIWIETPTNPLLKVVDIEAIVKIARSRGDII 643
A G D ++ V A++ + ++ +E +NPLL+V+DI A+ + AR+ G +
Sbjct: 132 FAARGTRIVTCDMCDLNAVDAALEAHRPDVLLVEQLSNPLLRVIDIRALAQRARAAGARL 191
Query: 644 VVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAI 772
V D+T +TP LQ+PL GAD+V++S TKY+ GH DV G +
Sbjct: 192 AV-DSTIVTPVLQQPLTLGADLVIHSATKYLGGHGDVAGGVVV 233
>UniRef50_Q46V95 Cluster: Cystathionine beta-lyase, bacterial; n=1;
Ralstonia eutropha JMP134|Rep: Cystathionine beta-lyase,
bacterial - Ralstonia eutropha (strain JMP134)
(Alcaligenes eutrophus)
Length = 418
Score = 116 bits (279), Expect = 7e-25
Identities = 71/222 (31%), Positives = 108/222 (48%), Gaps = 13/222 (5%)
Frame = +2
Query: 152 TIAIHAGQEPEKWNSAAVVTPIVTSTTF-----------KQPAPAEHTGFE-YGRSGNPT 295
T + AG+ PE++ V TPI ++T K+ AE G YGR G PT
Sbjct: 15 THLVCAGRHPERFGGV-VNTPIFRASTILAGSMAEWEEMKRARAAEEPGATTYGRYGTPT 73
Query: 296 RNTLEECLAALDGGKYGLTFASXXXXXXXXXXXX-NHGDHIVSSDDVYGGTNRLLRQVIA 472
LEE +A L+GG L F S + GDH++ +D Y T L +V+A
Sbjct: 74 TQALEEAVAGLEGGYRSLVFPSGLAAVSTALTALLSAGDHVLVTDSAYSPTRAFLERVLA 133
Query: 473 RLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVV 652
R G+ D ++ ++ NT+++++E+P + + DI AI A G VV+
Sbjct: 134 RFGVEVETYDPVGGTPIEALLRANTRVVYVESPGSETFDIQDIPAIAAAAHRHG-AYVVM 192
Query: 653 DNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVN 778
DNT+ TP +P G D+ + + TKY+ GHSD ++G N
Sbjct: 193 DNTWGTPLYFKPFAHGVDVSVQAATKYIVGHSDAMLGVVTCN 234
>UniRef50_Q1GNK9 Cluster: Cystathionine beta-lyase; n=4;
Sphingomonadales|Rep: Cystathionine beta-lyase -
Sphingopyxis alaskensis (Sphingomonas alaskensis)
Length = 400
Score = 116 bits (279), Expect = 7e-25
Identities = 68/210 (32%), Positives = 108/210 (51%), Gaps = 2/210 (0%)
Frame = +2
Query: 179 PEKWNSAAVVTPIVTSTTFKQPAPAEHTGFEYGRSGNPTRNTLEECLAALDGGKYG-LTF 355
P W ++ ++ V K A H YGR G PT L + L A++ G G L +
Sbjct: 36 PPVWRASTILYDTVAD--LKARGHATHDKLYYGRRGTPTVWALADALTAMEPGAAGTLLY 93
Query: 356 ASXXXXXXXXXXXX-NHGDHIVSSDDVYGGTNRLLRQVIARLGINTTFTDFTNIEKVKNA 532
S + GDH++ D Y T ++ARLG+ TT+ D +
Sbjct: 94 PSGVAANSAGLLALLSPGDHLLMVDSAYEPTRAFCDGMLARLGVTTTYYDPLVGAAIAEL 153
Query: 533 MQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQRPLXFGADIV 712
++ T++I++E+P + +V D+ AI +AR+RG ++ ++DNT+ TP L L G D+
Sbjct: 154 IRPETRLIFLESPGSLTFEVQDVPAITGVARARG-VLTMIDNTWATPLLFPALAHGVDVA 212
Query: 713 MYSLTKYMNGHSDVIMGAAIVNDKAIGXKL 802
M SLTKY+ GHSD +MG ++ +A+ KL
Sbjct: 213 MMSLTKYVGGHSDAMMG-SLTATRAVWPKL 241
>UniRef50_A5CVL3 Cluster: O-succinylhomoserine sulfhydrylase; n=3;
Bacteria|Rep: O-succinylhomoserine sulfhydrylase -
Vesicomyosocius okutanii subsp. Calyptogena okutanii
(strain HA)
Length = 388
Score = 116 bits (279), Expect = 7e-25
Identities = 58/165 (35%), Positives = 100/165 (60%), Gaps = 1/165 (0%)
Frame = +2
Query: 272 YGRSGNPTRNTLEECLAALDGGKYGL-TFASXXXXXXXXXXXXNHGDHIVSSDDVYGGTN 448
Y R NPT + E+ LA L+G + + T + GDHIV+S +++G +
Sbjct: 54 YARFTNPTVDAFEKKLAILEGAQACVATSSGMAAIFATIMALFKSGDHIVASRNMFGTSI 113
Query: 449 RLLRQVIARLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARS 628
+L +I + I+ +F + +++ +N ++ NTK+ +ETP+NPL +VV+I A+ +I+++
Sbjct: 114 IMLNTIITKFNIDISFVNLSDLSAWENTLKNNTKLFLLETPSNPLGEVVNINALSRISKA 173
Query: 629 RGDIIVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMG 763
I++ VDNT L+P LQ P+ GADIV++S TKY++G + G
Sbjct: 174 -NSILLAVDNTILSPALQTPITLGADIVIHSATKYIDGQGRCLAG 217
>UniRef50_Q8NM00 Cluster: Cystathionine beta-lyases/cystathionine
gamma-synthases; n=1; Corynebacterium glutamicum|Rep:
Cystathionine beta-lyases/cystathionine gamma-synthases
- Corynebacterium glutamicum (Brevibacterium flavum)
Length = 382
Score = 116 bits (278), Expect = 9e-25
Identities = 70/207 (33%), Positives = 103/207 (49%)
Frame = +2
Query: 152 TIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPAPAEHTGFEYGRSGNPTRNTLEECLAALD 331
T+ + AG+ P + A + PI S+T+ + YGR GN E + LD
Sbjct: 18 TVTVQAGR-PARTPGAPMNPPITLSSTYVHDSEKA-----YGRDGNDGWGAFEAAMGTLD 71
Query: 332 GGKYGLTFASXXXXXXXXXXXXNHGDHIVSSDDVYGGTNRLLRQVIARLGINTTFTDFTN 511
GG + ++++S G +V Y G + ++ AR + D N
Sbjct: 72 GG-FAVSYSSGLAAATSIADLVPTGGTVVLPKAAYYGVTNIFARMEARGRLKVRTVDADN 130
Query: 512 IEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQRPL 691
E+V A Q ++W+E+ NP + V DI AIV R G ++ VVD TF TP QRPL
Sbjct: 131 TEEVIAAAQ-GADVVWVESIANPTMVVADIPAIVDGVRGLG-VLTVVDATFATPLRQRPL 188
Query: 692 XFGADIVMYSLTKYMNGHSDVIMGAAI 772
GADIV+YS TK + GHSD+++G A+
Sbjct: 189 ELGADIVLYSATKLIGGHSDLLLGVAV 215
>UniRef50_A5ZYG7 Cluster: Putative uncharacterized protein; n=1;
Ruminococcus obeum ATCC 29174|Rep: Putative
uncharacterized protein - Ruminococcus obeum ATCC 29174
Length = 417
Score = 116 bits (278), Expect = 9e-25
Identities = 76/223 (34%), Positives = 110/223 (49%), Gaps = 9/223 (4%)
Frame = +2
Query: 143 GFATIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPAPAE--------HTGFEYGRSGNPTR 298
GF T +H G E + A V PI S+ F+ E G+ Y R NPT
Sbjct: 5 GFNTTLLH-GTEGNNPHGATQV-PIYQSSAFRHDTAEELEKIFSNKMAGYSYTRINNPTI 62
Query: 299 NTLEECLAALDGGKYGLTFASXXXXXXXXXXXX-NHGDHIVSSDDVYGGTNRLLRQVIAR 475
+ E+ +A L+GG + +S GDH+V++ +YGGT LL ++
Sbjct: 63 ESFEKRMAKLEGGIGSVACSSGMAALSMALMNVLQRGDHVVAAAGLYGGTVELLDELKV- 121
Query: 476 LGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVD 655
G+ TT+ + + + T+ ++ ET NP L V DI+ + +IA G I +VD
Sbjct: 122 YGVTTTYVKVNTPQAFEAEITPETRAVFAETIGNPKLDVTDIQGVAEIAHKYG-IPFLVD 180
Query: 656 NTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVNDK 784
NT TPYL PL GAD+V++S +KY+NG SD I G I K
Sbjct: 181 NTVATPYLINPLKLGADVVIHSSSKYINGSSDAISGILISGGK 223
>UniRef50_A1SMU4 Cluster: O-acetylhomoserine/O-acetylserine
sulfhydrylase; n=6; Bacteria|Rep:
O-acetylhomoserine/O-acetylserine sulfhydrylase -
Nocardioides sp. (strain BAA-499 / JS614)
Length = 428
Score = 116 bits (278), Expect = 9e-25
Identities = 74/220 (33%), Positives = 109/220 (49%), Gaps = 9/220 (4%)
Frame = +2
Query: 152 TIAIHAGQEPEK--WNSAAVVTPIVTSTTFKQPAPAEHT------GFEYGRSGNPTRNTL 307
T+A+HAGQE NS AV TS F A + G Y R NPT++
Sbjct: 7 TLAVHAGQEEHDPATNSRAVPIYQTTSYVFNDTEHAANLFSLAEPGNIYTRIMNPTQDVF 66
Query: 308 EECLAALDGGKYGLTFASXXXXXXXXXXXXNH-GDHIVSSDDVYGGTNRLLRQVIARLGI 484
E+ + L+GG L AS + GD+IV+ +YGGT L + + GI
Sbjct: 67 EQRMTQLEGGVGALAVASGSTATTYAVLNLTYAGDNIVALSTLYGGTYALFAHTLPQFGI 126
Query: 485 NTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTF 664
F D E + + + T++++ ET NP + VVDI A + A + G + +++DNT
Sbjct: 127 EVRFVDPDRPEDLAKVVDDKTRLVFGETVGNPRINVVDIPAWAEAAHALG-LPLIIDNTA 185
Query: 665 LTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVNDK 784
TPYL R GAD+V+++ TKY+ GH I G + + K
Sbjct: 186 PTPYLVRAFDQGADVVVHAATKYIGGHGTSIGGVIVDSGK 225
>UniRef50_Q1GQF1 Cluster: Cystathionine beta-lyase; n=1;
Sphingopyxis alaskensis|Rep: Cystathionine beta-lyase -
Sphingopyxis alaskensis (Sphingomonas alaskensis)
Length = 415
Score = 115 bits (277), Expect = 1e-24
Identities = 77/251 (30%), Positives = 119/251 (47%), Gaps = 10/251 (3%)
Frame = +2
Query: 80 DNKYVENKIGMADHGFLKQKPGFATIAIHAGQEPEKWNSAAVVTPIV--TSTTFKQPAPA 253
D K++E H + Q P T A+H G P + ++ P V ST A
Sbjct: 6 DGKWLEEPASPKGHAW--QDP---TRAVHGGPRPR--DQRGLINPPVDRASTIIYDSVEA 58
Query: 254 ---EHTGFE----YGRSGNPTRNTLEECLAALDGG-KYGLTFASXXXXXXXXXXXXNHGD 409
H G YG G T L E ++ L+GG +T + GD
Sbjct: 59 YMDRHQGLYDEVIYGLYGTRTTFALAEAVSELEGGCNTVITSSGTSAIALALTAFVAGGD 118
Query: 410 HIVSSDDVYGGTNRLLRQVIARLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLK 589
H++ +D VYG T + L V+AR G+ + ++ + NT++I++ETP +
Sbjct: 119 HLLVADCVYGPTRKFLTDVLARFGVEVEYFRPDIGAEIAGLCRSNTRLIYMETPGSQTFD 178
Query: 590 VVDIEAIVKIARSRGDIIVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAA 769
++D+ AI +ARSRG I+ +DNT+ TP +PL G DI + S TKY++GHSD ++G
Sbjct: 179 MIDVPAITAVARSRG-ILTALDNTWATPLFFKPLAHGVDISLASATKYLSGHSDCLLGTM 237
Query: 770 IVNDKAIGXKL 802
A+ +L
Sbjct: 238 TAASDAVYRQL 248
>UniRef50_Q5PBE9 Cluster: Cystathionine beta-lyase; n=1; Anaplasma
marginale str. St. Maries|Rep: Cystathionine beta-lyase
- Anaplasma marginale (strain St. Maries)
Length = 408
Score = 115 bits (276), Expect = 2e-24
Identities = 68/178 (38%), Positives = 99/178 (55%), Gaps = 1/178 (0%)
Frame = +2
Query: 272 YGRSGNPTRNTLEECLAALDGGKYGLTFASXXXXXXXXXXXX-NHGDHIVSSDDVYGGTN 448
YG P+ +L E + A+DGGKY L F S + G HI+ Y +
Sbjct: 75 YGNIAAPSCTSLAEDVRAIDGGKYALLFPSGLLCLTMACVTFCDAGSHILVPKKAYFKLH 134
Query: 449 RLLRQVIARLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARS 628
R +++ RLG + + + + E V E T +I+IET ++ L + D+ I++ A+
Sbjct: 135 RFIQESCPRLGRSVSV--YESAEDVPKMANEKTSLIFIETLSSSRLIIEDVSPIIEFAKK 192
Query: 629 RGDIIVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVNDKAIGXKL 802
RG I+V+ DN+ + P + P GADIVMYSLTKY GHSDV+MGA IVND+ I +L
Sbjct: 193 RG-IVVLCDNSCI-PTVFNPFNCGADIVMYSLTKYFGGHSDVMMGALIVNDEGIFDRL 248
>UniRef50_Q11C77 Cluster: Cystathionine beta-lyase; n=1;
Mesorhizobium sp. BNC1|Rep: Cystathionine beta-lyase -
Mesorhizobium sp. (strain BNC1)
Length = 388
Score = 115 bits (276), Expect = 2e-24
Identities = 68/223 (30%), Positives = 112/223 (50%), Gaps = 9/223 (4%)
Frame = +2
Query: 152 TIAIHAGQEPEKWNSAAVVTPIVTSTTF--------KQPAPAEHTGFEYGRSGNPTRNTL 307
T +HAG+ P+ + V P+ ++TF Q + G YGR+G PT
Sbjct: 10 TTLVHAGRGPQ-YRGNTVSPPVHRASTFLFDTLAEMDQASKTPFRGVFYGRNGTPTSVAF 68
Query: 308 EECLAALDGGKYGLTFASXXXXXXXXXXXX-NHGDHIVSSDDVYGGTNRLLRQVIARLGI 484
E+ +A + + AS N GDH++ D VY R ++AR+GI
Sbjct: 69 EDAMAKISNAHGAIATASGVSAIMGVMLGLLNSGDHVLIPDSVYDIVRRSADGMLARMGI 128
Query: 485 NTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTF 664
+ D +++ ++ NT++I++E+P + +V D+ AIV +A++R +I +DNT+
Sbjct: 129 EYEYYDPVVGAGIESLLRPNTRLIYLESPGSGTFEVQDVPAIVAVAKAR-NIRTAIDNTW 187
Query: 665 LTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVNDKAIG 793
TP RPL G D V+ + TKY+ GHSD ++G N+ G
Sbjct: 188 ATPVFFRPLELGVDAVIEAGTKYIVGHSDAMLGVVAANELTYG 230
>UniRef50_A5CMC2 Cluster: O-acetylhomoserine (Thiol)-lyase; n=2;
Actinomycetales|Rep: O-acetylhomoserine (Thiol)-lyase -
Clavibacter michiganensis subsp. michiganensis (strain
NCPPB 382)
Length = 453
Score = 115 bits (276), Expect = 2e-24
Identities = 72/220 (32%), Positives = 111/220 (50%), Gaps = 10/220 (4%)
Frame = +2
Query: 143 GFATIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPAPAE--------HTGFEYGRSGNPTR 298
GF T +HAG + + A V+P+ S F + AE G+ Y R+GNPT
Sbjct: 26 GFTTRQVHAGSAIDG-DHGARVSPVHLSAGFVFDSFAEARDRFAGVDEGYLYTRNGNPTT 84
Query: 299 NTLEECLAALDGGKYGLTFASXXXXXXXXXXXX-NHGDHIVSSDDVYGGTNRLLRQVIAR 475
+ +E LA L+GG + AS GD I+SS +Y G L RQ + R
Sbjct: 85 DEVERRLAELEGGTEAILLASGQAATTTALLAILQAGDRILSSSSIYEGNRGLFRQNLGR 144
Query: 476 LGINTTFTD-FTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVV 652
LGI F D ++++ + T++++ E NP ++D+ I +A G + VV
Sbjct: 145 LGIGVDFVDDHRDLDEWARRITPETRVLFGEPIPNPKNDLLDLAGIADVAHRHG-LPFVV 203
Query: 653 DNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAI 772
D+T TPYL RP+ GAD+V++S +K++ GH V+ G +
Sbjct: 204 DDTLATPYLLRPIEHGADVVVHSTSKFLAGHGSVLGGVVV 243
>UniRef50_Q8FRS9 Cluster: O-acetylhomoserine sulfhydrylase; n=8;
Bacteria|Rep: O-acetylhomoserine sulfhydrylase -
Corynebacterium efficiens
Length = 438
Score = 114 bits (274), Expect = 3e-24
Identities = 79/224 (35%), Positives = 113/224 (50%), Gaps = 10/224 (4%)
Frame = +2
Query: 143 GFATIAIHAGQEPEKWNSAAVVTPIVTSTTF--------KQPAPAEHTGFEYGRSGNPTR 298
GF T +IHAGQ P ++ + PI +T F KQ E G Y R NPT
Sbjct: 14 GFETRSIHAGQ-PVDSDTGSRNLPIHLTTAFVFDSAEHAKQRFALEDLGPVYTRLTNPTV 72
Query: 299 NTLEECLAALDGGKYGLTFASXXXXXXXXXXXXNH-GDHIVSSDDVYGGTNRLLRQVIAR 475
+E + L+GG + + FAS G H+V+S +YGGT L + R
Sbjct: 73 EAVENRINNLEGGAHTVFFASGQAATTAAILNLGGAGSHVVTSPRLYGGTETLFLVTLKR 132
Query: 476 LGINTTFTDFTNI-EKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVV 652
LGI TF + + E + A+++NT + ET NP V+DI A+ ++A R + ++V
Sbjct: 133 LGIEFTFVENPDDPESWQAAVRDNTIAFFGETFANPQADVLDIPAVSEVAH-RNQVPLIV 191
Query: 653 DNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVNDK 784
DNT T L RP+ GADIV+ SLTK+ G+ + GA + K
Sbjct: 192 DNTIATAALVRPIELGADIVVASLTKFYTGNGSALGGALVDGGK 235
>UniRef50_Q47S97 Cluster: Cystathionine gamma-synthase; n=1;
Thermobifida fusca YX|Rep: Cystathionine gamma-synthase
- Thermobifida fusca (strain YX)
Length = 406
Score = 114 bits (274), Expect = 3e-24
Identities = 62/175 (35%), Positives = 93/175 (53%), Gaps = 6/175 (3%)
Frame = +2
Query: 266 FEYGRSGNPTRNTLEECLAALDGGK-----YGLTFASXXXXXXXXXXXXNH-GDHIVSSD 427
+ Y R +P + +AAL+G +G FAS H G H+V+S
Sbjct: 53 YAYARIDSPNSDAFAAAVAALEGAHLEGEVHGQGFASGMAAISITLLALTHAGAHVVASR 112
Query: 428 DVYGGTNRLLRQVIARLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEA 607
+YG T +LL V+ R G+ F D T+ V+ A + T +++ ET NP + V D+
Sbjct: 113 ALYGNTYKLLDVVLRRFGVAVDFVDITDPAAVRAAFRPETVLVYTETLANPTMTVSDLPV 172
Query: 608 IVKIARSRGDIIVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAI 772
+ +A G ++VVD+TF +P + RPL GADIV++S TKY+ GHSD G A+
Sbjct: 173 LAALAHEAG-ALLVVDSTFASPVVCRPLEHGADIVLHSATKYLGGHSDATGGVAV 226
>UniRef50_Q1IQ69 Cluster: Cystathionine beta-lyase; n=6;
Bacteria|Rep: Cystathionine beta-lyase - Acidobacteria
bacterium (strain Ellin345)
Length = 407
Score = 114 bits (274), Expect = 3e-24
Identities = 73/232 (31%), Positives = 114/232 (49%), Gaps = 10/232 (4%)
Frame = +2
Query: 137 KPGFATIAIHAGQE-PEKWNSAAVVTPIVTSTTFKQPAPAEHT--------GFEYGRSGN 289
K + T IH PE + S +VTP +T P T G+ YG G
Sbjct: 23 KKSWKTKLIHGDSHAPEGFRS--LVTPTYRGSTVLFPDAESVTDQWDQHRVGYTYGLYGT 80
Query: 290 PTRNTLEECLAALDGGKYGL-TFASXXXXXXXXXXXXNHGDHIVSSDDVYGGTNRLLRQV 466
PT L + L+ G++ + T N GDHI+ +++YG +L V
Sbjct: 81 PTTLELAARVCELEDGEHTIITAGGQGAISLIQLSLLNAGDHILIPENIYGPNRKLAYSV 140
Query: 467 IARLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIV 646
+ R G+ T + +++NT+++W E+P + ++V D+ AI K A +RG +V
Sbjct: 141 LKRFGVEVTVYPPLIGAGIAELIKDNTRLVWCESPGSLTMEVQDVPAIAKAAHARG-ALV 199
Query: 647 VVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVNDKAIGXKL 802
V+DNT+ + R G D+ M +LTKY+ GHSDV++GA + D+AI KL
Sbjct: 200 VLDNTWSSGIFFRAFDHGVDVEMQALTKYVAGHSDVLLGAITIRDRAIYEKL 251
>UniRef50_A1SSS1 Cluster: Cystathionine beta-lyase; n=10;
Gammaproteobacteria|Rep: Cystathionine beta-lyase -
Psychromonas ingrahamii (strain 37)
Length = 407
Score = 113 bits (271), Expect = 6e-24
Identities = 66/211 (31%), Positives = 104/211 (49%), Gaps = 10/211 (4%)
Frame = +2
Query: 182 EKWNSAAVVTPIVTSTT--FKQPAPAEHTG-------FEYGRSGNPTRNTLEECLAALDG 334
+KW V P+V ++T F G YGR G PT +E +A L+G
Sbjct: 29 KKWTKGVVNPPVVRASTMLFDTMEDMRFAGKNKNNGEMYYGRRGGPTHFAFQEAIAELEG 88
Query: 335 GKYGLTFASXXXXXXXXXXXX-NHGDHIVSSDDVYGGTNRLLRQVIARLGINTTFTDFTN 511
G + S GDH++ D+ Y T L ++A GI TT+ D
Sbjct: 89 GAGTALYPSGTAAISSALMSFLKAGDHLLMLDNAYEPTRALCDTLLAGFGIETTYYDPLI 148
Query: 512 IEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQRPL 691
+ +Q NTK++++E+P + +++ D+ + +IA ++IV++DNT+ +P RP
Sbjct: 149 GAGISELIQPNTKVLFLESPGSITMEIQDVPTLSRIAHEN-NLIVMLDNTWASPINSRPF 207
Query: 692 XFGADIVMYSLTKYMNGHSDVIMGAAIVNDK 784
G DI + + TKY+ GHSDV+MG A N K
Sbjct: 208 EMGVDISIQAATKYIVGHSDVMMGTATANTK 238
>UniRef50_Q97W69 Cluster: O-succinylhomoserine (Thiol)-lyase; n=5;
Archaea|Rep: O-succinylhomoserine (Thiol)-lyase -
Sulfolobus solfataricus
Length = 376
Score = 112 bits (270), Expect = 9e-24
Identities = 60/193 (31%), Positives = 103/193 (53%), Gaps = 1/193 (0%)
Frame = +2
Query: 194 SAAVVTPIVTSTTFKQPAPAEHTGFEYGRSGNPTRNTLEECLAALDGGKYGLTFASXXXX 373
+ A+ TPI ++ + P E + Y R NPT L + + L+ + G+ F+S
Sbjct: 16 TGAITTPIYQTSAYHYP---EGEKYRYSRESNPTVLELAKKIVELENAEMGIAFSSGMGA 72
Query: 374 XXXXXXXX-NHGDHIVSSDDVYGGTNRLLRQVIARLGINTTFTDFTNIEKVKNAMQENTK 550
G+ ++ D++G + R + G+N + N ++ A +
Sbjct: 73 ISTTALALLKPGNSVLVHRDMFGRSYRFFTDYLKNWGVNVEASYPGNNNIIEKAKSKRYD 132
Query: 551 MIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQRPLXFGADIVMYSLTK 730
+I++E TNPLL+V+D+ + K+A+ +G I++V D TF TP Q+PL GADIV++S +K
Sbjct: 133 VIFVENITNPLLRVIDVAELSKVAKEQGSILIV-DATFSTPINQKPLELGADIVVHSASK 191
Query: 731 YMNGHSDVIMGAA 769
++ GH+DVI G A
Sbjct: 192 FLAGHNDVIAGLA 204
>UniRef50_Q5LWC9 Cluster: Cys/Met metabolism PLP-dependent enzyme
family protein; n=5; cellular organisms|Rep: Cys/Met
metabolism PLP-dependent enzyme family protein -
Silicibacter pomeroyi
Length = 403
Score = 112 bits (269), Expect = 1e-23
Identities = 71/217 (32%), Positives = 107/217 (49%), Gaps = 9/217 (4%)
Frame = +2
Query: 143 GFATIAIHAGQEPEKWNSAAVVTPIVTSTT--------FKQPAPAEHTGFEYGRSGNPTR 298
G T AIHAG+ P+ A+ PI S+T F + + Y R NPT
Sbjct: 9 GPMTTAIHAGEAPDPATLASA-PPIHMSSTYVSEDVLGFSAHDLTPQSPYAYSRWANPTV 67
Query: 299 NTLEECLAALDGGKYGLTFASXXXXXXXXXXXX-NHGDHIVSSDDVYGGTNRLLRQVIAR 475
LE +AA+ G + L AS + GDH++ SD Y G L R + R
Sbjct: 68 AMLEAKIAAMQGTEACLCTASGMAAAAAIFFTFLSAGDHVIVSDVSYAGVAELARDTLPR 127
Query: 476 LGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVD 655
+GI + D +++ V A++ T++I ETP NP+ ++ D+ AI +AR G ++ D
Sbjct: 128 MGIAVSTVDMSDLAAVAAAIRPETRLIHTETPVNPIGRLTDLAAISALARQAG-ALLSCD 186
Query: 656 NTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGA 766
TF +P + G D+ M+S+TKY+ GH D + GA
Sbjct: 187 ATFASPLGMDTVALGVDLTMHSVTKYICGHGDAVAGA 223
>UniRef50_Q2JBH0 Cluster: O-succinylhomoserine sulfhydrylase; n=1;
Frankia sp. CcI3|Rep: O-succinylhomoserine sulfhydrylase
- Frankia sp. (strain CcI3)
Length = 409
Score = 112 bits (269), Expect = 1e-23
Identities = 70/209 (33%), Positives = 109/209 (52%), Gaps = 9/209 (4%)
Frame = +2
Query: 143 GFATIAIHAG--QEPEKWNSAAVVTPIVTSTTFKQPAPA------EHTGFEYGRSGNPTR 298
G AT A+ AG Q + +S A+V + +S F A G Y R NPT
Sbjct: 16 GLATEAVRAGHRQSVDDQHSEALV--LTSSYLFDDSHDAAEKFAQRRPGNVYVRFTNPTV 73
Query: 299 NTLEECLAALDGGKYGLTFASXXXXXXXXXXXX-NHGDHIVSSDDVYGGTNRLLRQVIAR 475
EE +A L+G + + AS GDH++ ++ V+G T RL + R
Sbjct: 74 RAFEERVARLEGAESAVATASGMAAFLAVSLGLLRGGDHVLLAEGVFGTTTRLYAHYLDR 133
Query: 476 LGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVD 655
G+ TT T+ AM+ T+M+ +E+PTNP++ V DI + ++A + G +++VD
Sbjct: 134 FGVMTTVVPVTDPAAWARAMRAQTRMLVVESPTNPVMAVADIRYLAELAHAAG-ALLLVD 192
Query: 656 NTFLTPYLQRPLXFGADIVMYSLTKYMNG 742
NT TP Q+P+ FGAD+V++S KY++G
Sbjct: 193 NTLCTPVFQQPIVFGADLVLHSAGKYIDG 221
>UniRef50_O02215 Cluster: Putative uncharacterized protein; n=3;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 451
Score = 112 bits (269), Expect = 1e-23
Identities = 67/207 (32%), Positives = 108/207 (52%), Gaps = 11/207 (5%)
Frame = +2
Query: 191 NSAAVVTPIVTSTTFK-----QPAPAEH-TGFEYGRSGNPTRNTLEECLAALDGGKYGLT 352
N+ VV PI S+T++ Q H F Y R GNPT +E + ++GG L
Sbjct: 78 NADPVVVPIYHSSTYRFKTVDQFNEDNHGANFVYRRCGNPTTENVEVVINEIEGGAGSLL 137
Query: 353 FASXXXXXXXXXXXX-NHGDHIVSSDDVYGGTNRLLRQVIARLGINTTFTDFTNIEK--- 520
+ S + G H++ + +Y GT+ + + +AR G+ T D +
Sbjct: 138 YNSGLAAISAVFLEFLSSGAHMIVMNPIYSGTSSFINETLARFGVEITSVDVEKEKDFAG 197
Query: 521 -VKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQRPLXF 697
V+ A++ NTKMI+ E+ NP + V DI +++A+ + I+ +D TF +PY +PL
Sbjct: 198 AVEKAIRPNTKMIYFESIANPTMAVPDILGTIEVAK-KYKILTCLDATFSSPYNIQPLKL 256
Query: 698 GADIVMYSLTKYMNGHSDVIMGAAIVN 778
GADI ++S +KY+ GH+DVI G V+
Sbjct: 257 GADISLHSCSKYIGGHTDVIAGVVTVS 283
>UniRef50_Q07703 Cluster: Cystathionine beta-lyase; n=6;
Burkholderiales|Rep: Cystathionine beta-lyase -
Bordetella avium
Length = 396
Score = 112 bits (269), Expect = 1e-23
Identities = 59/178 (33%), Positives = 101/178 (56%), Gaps = 1/178 (0%)
Frame = +2
Query: 272 YGRSGNPTRNTLEECLAALDGGKYG-LTFASXXXXXXXXXXXXNHGDHIVSSDDVYGGTN 448
YGR G T LE+ A L+GG + L + + G+H + +D YG +
Sbjct: 64 YGRMGMDTHAALEQVFAELEGGTHCYLASSGLAGISMVFLSLLSAGEHALVADCAYGPVH 123
Query: 449 RLLRQVIARLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARS 628
L V++RLGI+ TF D + + ++ T++I+ E P + L +++D+ A+ + A+
Sbjct: 124 ELHEAVLSRLGIDVTFFDAK--ADLASLVRPTTRLIFAEAPGSLLFEMLDMPALARFAKQ 181
Query: 629 RGDIIVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVNDKAIGXKL 802
D+I+ DNT+ + Y+ RPL GA + + + TKY+ GHSD+++GA + ND+AI +L
Sbjct: 182 H-DLILATDNTWGSGYIYRPLTLGAQVSVIAGTKYVGGHSDLMLGAVVTNDEAIAKRL 238
>UniRef50_Q82YZ5 Cluster: Cystathionine gamma-synthase, putative;
n=1; Enterococcus faecalis|Rep: Cystathionine
gamma-synthase, putative - Enterococcus faecalis
(Streptococcus faecalis)
Length = 395
Score = 111 bits (267), Expect = 2e-23
Identities = 57/174 (32%), Positives = 96/174 (55%), Gaps = 1/174 (0%)
Frame = +2
Query: 254 EHTGFEYGRSGNPTRNTLEECLAALDGGKYGLTFASXXXXXXXXXXXX-NHGDHIVSSDD 430
E + Y R NPT LE+ +A L+ G+ FAS GDH++ +
Sbjct: 49 EKNNYVYTRGTNPTTEILEKKIARLERGEKCKVFASGMGAISATLFTLLQQGDHVLMVNT 108
Query: 431 VYGGTNRLLRQVIARLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAI 610
+YG + + Q + + G++ T D E++ +QENTK+I+ E+P++ +++D+E I
Sbjct: 109 IYGESVSFV-QYLEKFGVSLTKVDVAETEELFQFVQENTKVIYFESPSSQKFELLDLEKI 167
Query: 611 VKIARSRGDIIVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAI 772
+A+ G V+DNT+ +P Q PL D+V++S +KY+ GHSD++ GA I
Sbjct: 168 TALAQKIG-AYTVIDNTWASPLFQHPLCHNVDLVIHSCSKYIGGHSDIVAGAVI 220
>UniRef50_A7DHV1 Cluster: O-acetylhomoserine
aminocarboxypropyltransferase precursor; n=2;
Methylobacterium extorquens PA1|Rep: O-acetylhomoserine
aminocarboxypropyltransferase precursor -
Methylobacterium extorquens PA1
Length = 448
Score = 111 bits (267), Expect = 2e-23
Identities = 74/215 (34%), Positives = 108/215 (50%), Gaps = 9/215 (4%)
Frame = +2
Query: 146 FATIAIHAGQEPEKWNSAAVVTPIVTSTTF-----KQPAPA---EHTGFEYGRSGNPTRN 301
FAT A+HAG P+ A V PI + F +Q A TGF Y R NPT
Sbjct: 10 FATQAVHAGAAPDPATGARV-QPIYFTNGFVFDSTEQAADIFAMRKTGFSYSRGSNPTVA 68
Query: 302 TLEECLAALDGGKYGLTFASXXXXXXXXXXXXNH-GDHIVSSDDVYGGTNRLLRQVIARL 478
LE +AAL+G K + +S GD V+S ++GG+ L+R++ R
Sbjct: 69 ALERRVAALEGAKAAVAVSSGQSAVLLVMMTLMQTGDAYVASPRLFGGSLGLMRRLEGRY 128
Query: 479 GINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDN 658
+ F E + A+ TK I E+ NP V+DIE I +A+ G + +V+DN
Sbjct: 129 DLTPQFAADLTPEAFEAAITPQTKAIICESIVNPCATVMDIEGIAAVAKRHG-LPLVIDN 187
Query: 659 TFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMG 763
T +P L RP+ +GADI+++S +K++ G VI G
Sbjct: 188 TLASPALIRPIEYGADIIVHSTSKFLGGSGQVIGG 222
>UniRef50_P53101 Cluster: Cystathionine beta-lyase; n=5;
Saccharomycetales|Rep: Cystathionine beta-lyase -
Saccharomyces cerevisiae (Baker's yeast)
Length = 465
Score = 111 bits (266), Expect = 3e-23
Identities = 78/232 (33%), Positives = 112/232 (48%), Gaps = 15/232 (6%)
Frame = +2
Query: 152 TIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPAPAEHT-GFEYGRSGNPTRNTLEECLAAL 328
T+ ++ G + ++ +A V P+ STTFK E ++Y RSGNPTR+ L+ + L
Sbjct: 8 TVVVNTGSQNDQ--HSASVPPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIGKL 65
Query: 329 D--------GGKYGLTFASXXXXXXXXXXXX-NHGDHIVSSDDVYGGTNRLLRQVIARLG 481
G+T NH I++ DD+YGGT RLL +
Sbjct: 66 YRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQSH 125
Query: 482 INTTFTDFTNIEKVKNAMQENTKM--IWIETPTNPLLKVVDIEAIVKIARS-RGDIIVVV 652
+ D ++ EK K Q K+ + +E+PTNPL KVVDI I++ + D VVV
Sbjct: 126 AVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTVVV 185
Query: 653 DNTFLTPYLQRPLXF--GADIVMYSLTKYMNGHSDVIMGAAIVNDKAIGXKL 802
DNT ++ PL G D+V S TKY+NGH D++ G I I KL
Sbjct: 186 DNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKL 237
>UniRef50_Q7M844 Cluster: O-ACETYLHOMOSERINE (THIOL)-LYASE; n=1;
Wolinella succinogenes|Rep: O-ACETYLHOMOSERINE
(THIOL)-LYASE - Wolinella succinogenes
Length = 422
Score = 110 bits (264), Expect = 5e-23
Identities = 70/227 (30%), Positives = 113/227 (49%), Gaps = 10/227 (4%)
Frame = +2
Query: 152 TIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPAPAEH---------TGFEYGRSGNPTRNT 304
T+AI AG E K ++ PI +T +K EH G Y R NPT +
Sbjct: 5 TLAIQAGYEKGK-GEKSIAVPIYQTTAYKFD-DTEHGANLFDLKELGNIYTRIMNPTTDV 62
Query: 305 LEECLAALDGGKYGLTFASXXXXXXXXXXX-XNHGDHIVSSDDVYGGTNRLLRQVIARLG 481
LE+ +A L+GG L AS G++I+++ +YGGT ++R G
Sbjct: 63 LEKRVALLEGGVAALASASGMASIFYAVANLAQSGENIIATTQLYGGTLNQFTHTLSRFG 122
Query: 482 INTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNT 661
I F D + ++ + + ++ ++ E+ TNP + V +I+ + KIA G I+ +VDNT
Sbjct: 123 IEVRFFDGNHPQEARALIDSKSRALFFESLTNPSIDVPEIDTLAKIADEYG-IVSIVDNT 181
Query: 662 FLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVNDKAIGXKL 802
TP + RP+ G D+V++S +KYM G + +G +V + KL
Sbjct: 182 VATPAICRPIEHGVDVVVHSASKYMGGQG-LAIGGVLVESARVAEKL 227
>UniRef50_Q2K0N3 Cluster: Cystathionine gamma-synthase protein; n=7;
Alphaproteobacteria|Rep: Cystathionine gamma-synthase
protein - Rhizobium etli (strain CFN 42 / ATCC 51251)
Length = 390
Score = 110 bits (264), Expect = 5e-23
Identities = 57/165 (34%), Positives = 93/165 (56%), Gaps = 1/165 (0%)
Frame = +2
Query: 272 YGRSGNPTRNTLEECLAALDGGKYGLTFASXXXXXXXXXXXX-NHGDHIVSSDDVYGGTN 448
Y R NPT E+ LA L+GG+ L FAS GD IV+ VY
Sbjct: 57 YTRGLNPTVRAFEDMLAKLEGGEDALGFASGMAAISSAVLSFVEPGDRIVAVKHVYPDAF 116
Query: 449 RLLRQVIARLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARS 628
RL ++ R+ I T+ D + E V A+ K++++E+PT+ +++ D+ A+ +A+
Sbjct: 117 RLFGTILKRMKIEVTYVDGRDEEAVARALP-GAKLLYLESPTSWVMEAHDVGALAALAKR 175
Query: 629 RGDIIVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMG 763
G + ++DN++ +P+ QRPL G D+V++S +KY+ GHSDV+ G
Sbjct: 176 HG-AVSMIDNSWASPFFQRPLTLGVDLVIHSASKYLGGHSDVVAG 219
>UniRef50_Q76K51 Cluster: O-acetyl-L-homoserine sulfhydrylase; n=4;
Thermus|Rep: O-acetyl-L-homoserine sulfhydrylase -
Thermus thermophilus
Length = 412
Score = 110 bits (264), Expect = 5e-23
Identities = 70/216 (32%), Positives = 109/216 (50%), Gaps = 7/216 (3%)
Frame = +2
Query: 146 FATIAIHAGQEPEKWNSAAVVTPIVTSTTFK-----QPAPAEHTGFEYGRSGNPTRNTLE 310
+ T+A+ AG + + + V + FK Q A G+ Y R +PT LE
Sbjct: 3 YTTLAVLAGLPEDPHGAVGLPIYAVAAYGFKTLEEGQERFATGEGYVYARQKDPTAKALE 62
Query: 311 ECLAALDGGKYGLTFASXXXXXXXXXXXX-NHGDHIVSSDDVYGGTNRLLRQVIARLGIN 487
E L AL+G + AS GD +V++ ++G T L QV++ +G+
Sbjct: 63 ERLKALEGALEAVVLASGQAATFAALLALLRPGDEVVAAKGLFGQTIGLFGQVLSLMGVT 122
Query: 488 TTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTF- 664
+ D E V+ A+ T+ +++ET NP L V D+EA+ +A G + +VVDNTF
Sbjct: 123 VRYVD-PEPEAVREALSAKTRAVFVETVANPALLVPDLEALATLAEEAG-VALVVDNTFG 180
Query: 665 LTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAI 772
L RPL +GA +V+ SLTK+ +GH V+ GA +
Sbjct: 181 AAGALCRPLAWGAHVVVESLTKWASGHGSVLGGAVL 216
>UniRef50_A1I7W3 Cluster: O-acetylhomoserine
aminocarboxypropyltransferase; n=1; Candidatus
Desulfococcus oleovorans Hxd3|Rep: O-acetylhomoserine
aminocarboxypropyltransferase - Candidatus Desulfococcus
oleovorans Hxd3
Length = 419
Score = 110 bits (264), Expect = 5e-23
Identities = 69/223 (30%), Positives = 107/223 (47%), Gaps = 9/223 (4%)
Frame = +2
Query: 146 FATIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPAPAE-HTGFE-------YGRSGNPTRN 301
F+T +H + +W A + PI +T F F Y R NPT
Sbjct: 9 FSTRVVHHTRPVAEWQGATL-PPIFQTTAFAHDTAENLSNAFAGKNADPIYSRLTNPTNQ 67
Query: 302 TLEECLAALDGGKYGLTFASXXXXXXXX-XXXXNHGDHIVSSDDVYGGTNRLLRQVIARL 478
LE+ +A L+GG + AS GD V+ ++ T +L + +
Sbjct: 68 ALEKVMAGLEGGAGTIAMASGMAAVANTCMALLRAGDEFVAGTSLFMSTYQLFAGIFKKY 127
Query: 479 GINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDN 658
GI + +++ V NA+ + T+ ++IET NP++ V DI A+ +A G + +VVDN
Sbjct: 128 GITVRAVNPLDLDAVNNAVTDKTRFVYIETIGNPVMDVPDIRALADLAHGHG-LPLVVDN 186
Query: 659 TFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVNDKA 787
T TP+L RPL GAD V++S TKY+ GH MG +++ A
Sbjct: 187 TLGTPFLCRPLELGADAVIHSTTKYLCGHG-AAMGGVVIDGGA 228
>UniRef50_O69592 Cluster: O-succinylhomoserine sulfhydrylase; n=19;
Bacteria|Rep: O-succinylhomoserine sulfhydrylase -
Mycobacterium leprae
Length = 426
Score = 109 bits (263), Expect = 6e-23
Identities = 66/219 (30%), Positives = 110/219 (50%), Gaps = 7/219 (3%)
Frame = +2
Query: 149 ATIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPAPAEH--TG----FEYGRSGNPTRNTLE 310
AT+ + G ++ A + + ++ AE TG F Y R GNPT E
Sbjct: 40 ATVGVRGGLLRSRFEETAETMYLTSGYVYESAVVAEKSFTGELDHFVYSRYGNPTVTMFE 99
Query: 311 ECLAALDGGKYGLTFASXXXXXXXXXXXX-NHGDHIVSSDDVYGGTNRLLRQVIARLGIN 487
E L ++G AS GD +V++ ++G + +++ R G+
Sbjct: 100 ERLRLIEGAPAAFVTASGMAAVFTSLGALLASGDRLVAARSLFGSCFVVCNEILPRWGVE 159
Query: 488 TTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFL 667
T F D ++ + + A+ T+ ++ ETP+NP+ +VDI A+ ++A + G VV+DN F
Sbjct: 160 TVFVDGEDLVQWEQALSVPTQAVFFETPSNPMQSLVDIAAVTELAHAAG-AKVVLDNAFA 218
Query: 668 TPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVNDK 784
TP LQ L G D+V+YS TK+++G V +G AI+ D+
Sbjct: 219 TPLLQHGLPLGVDVVIYSGTKHIDGQGRV-LGGAILGDR 256
>UniRef50_Q5GSE3 Cluster: Cystathionine beta-lyase; n=5;
Wolbachia|Rep: Cystathionine beta-lyase - Wolbachia sp.
subsp. Brugia malayi (strain TRS)
Length = 413
Score = 109 bits (261), Expect = 1e-22
Identities = 59/170 (34%), Positives = 90/170 (52%), Gaps = 1/170 (0%)
Frame = +2
Query: 266 FEYGRSGNPTRNTLEECLAALDGGKYGLTFASXXXXXXXXXXX-XNHGDHIVSSDDVYGG 442
+ YG G PT + LA ++G L + S G H++ D+ Y
Sbjct: 60 YSYGSVGTPTVHYFSNALAEIEGRGQALIYPSGLFALTFAILTFARAGSHVLIQDNSYYR 119
Query: 443 TNRLLRQVIARLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIA 622
R + + + TF D T + + + +Q NT++I IETP + +V +IE IVKIA
Sbjct: 120 LRRFAENELPKRRVEVTFYDPT--QDIASLIQSNTRLIMIETPGSVTFEVSNIEHIVKIA 177
Query: 623 RSRGDIIVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAI 772
+ I+ V DN++ TP L RPL +G D+ +Y +TKY+ GHSD++MGA I
Sbjct: 178 KEH-KIVTVCDNSWATPLLFRPLDYGIDVALYGVTKYIAGHSDLLMGAII 226
>UniRef50_A6PIC3 Cluster: Cystathionine beta-lyase; n=1; Shewanella
sediminis HAW-EB3|Rep: Cystathionine beta-lyase -
Shewanella sediminis HAW-EB3
Length = 411
Score = 108 bits (260), Expect = 1e-22
Identities = 57/171 (33%), Positives = 91/171 (53%), Gaps = 1/171 (0%)
Frame = +2
Query: 272 YGRSGNPTRNTLEECLAALDGGKYGLTFASXXXXXXXXXXXX-NHGDHIVSSDDVYGGTN 448
YGR G PT + +A L+GG + S GDH++ D Y T
Sbjct: 71 YGRRGGPTHFAFQAAIAELEGGVGTALYPSGSAAISGALLSFLKAGDHLLMVDSAYEPTR 130
Query: 449 RLLRQVIARLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARS 628
L +++A GI TT+ D + ++ NTK++++E+P + ++V D+ + +IA
Sbjct: 131 DLCNKLLAGFGIETTYYDPMIGAGISELIRPNTKVLFLESPGSITMEVQDVPTLSEIAHK 190
Query: 629 RGDIIVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVND 781
DI+V++DNT+ +P RP G DI + + TKY+ GHSDV+MG A N+
Sbjct: 191 H-DIVVMLDNTWASPINSRPFDMGVDISIQAATKYIVGHSDVMMGTATSNE 240
>UniRef50_A5G088 Cluster: Cystathionine gamma-synthase; n=1;
Acidiphilium cryptum JF-5|Rep: Cystathionine
gamma-synthase - Acidiphilium cryptum (strain JF-5)
Length = 416
Score = 108 bits (260), Expect = 1e-22
Identities = 81/236 (34%), Positives = 113/236 (47%), Gaps = 31/236 (13%)
Frame = +2
Query: 152 TIAIHAGQEPEKWNSAAVVTPIVTSTTF------------------KQPAPAEHTGFEYG 277
TIA+ G +P + N AA P+ S+TF + P + G+ Y
Sbjct: 8 TIAVGHGYDPARHNGAAK-PPVYMSSTFVYRDAAHARSAHEGYAAGRAPDSGDAEGYIYA 66
Query: 278 RSGNPTRNTLEECLAALDGGKYGLTFASXXXXXXXXXXXX-NHGDHIVSSDDVYGGTNRL 454
R +P L+ +AALDG + F S GD ++ + +YGGT+ L
Sbjct: 67 RLDHPNLQMLQARMAALDGAEACAAFGSGMAAVATALLSLVRPGDSVLHTSPLYGGTDGL 126
Query: 455 LRQVIA-RLGIN-TTFTDFTNIEKVKNAM-----QENTKMIWIETPTNPLLKVVDIEAIV 613
L V+A LG+ D + V+ A +WIETP+NPL + DI I
Sbjct: 127 LTGVMAPELGVRPVAIADALDEGSVREAAAGALAHGPLAAVWIETPSNPLAGLADIALIA 186
Query: 614 KIAR--SRGDI---IVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGA 766
++AR + G +V+VDNTFL P LQ PL GAD+ M SLTKY GHSD++ GA
Sbjct: 187 RVAREAAAGQARPPVVIVDNTFLGPTLQAPLRHGADLCMTSLTKYAGGHSDLLGGA 242
>UniRef50_A0VE37 Cluster: Cystathionine beta-lyase; n=2;
Comamonadaceae|Rep: Cystathionine beta-lyase - Delftia
acidovorans SPH-1
Length = 407
Score = 108 bits (260), Expect = 1e-22
Identities = 69/237 (29%), Positives = 119/237 (50%), Gaps = 13/237 (5%)
Frame = +2
Query: 131 KQKP-GFATIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPAPAEHTGFE-----------Y 274
K +P G +T +HAG + S V P+V ++T + A + Y
Sbjct: 7 KHRPLGPSTRLLHAGTPQLQGGSGPVNVPVVRTSTVRFADSAAYADLHHRREAGERLASY 66
Query: 275 GRSGNPTRNTLEECLAALDGGKYG-LTFASXXXXXXXXXXXXNHGDHIVSSDDVYGGTNR 451
GR G T LE+ + AL+GG LT + + GDH + +D VY R
Sbjct: 67 GRHGLDTHRALEDAVVALEGGHRAFLTPSGLSAITLVLIALLSPGDHALVADSVYSPVRR 126
Query: 452 LLRQVIARLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSR 631
+ ++ RLGI + + + + ++ NT+++++E+P++ L +V+D+ A+ +AR
Sbjct: 127 VDATLLQRLGITLEYFSPSR-DDLAGKIRPNTRLVYLESPSSLLYEVLDLPALAAVARRH 185
Query: 632 GDIIVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVNDKAIGXKL 802
G I V DNT+ + +PL GA++ + + TKY+ GHSDV+ G I + A+ K+
Sbjct: 186 G-IAVATDNTWSGGWFYQPLEHGANLSIQAATKYIAGHSDVMQGIVITDGPALSKKI 241
>UniRef50_A5EU95 Cluster: Cystathionine beta-lyase; n=1;
Bradyrhizobium sp. BTAi1|Rep: Cystathionine beta-lyase -
Bradyrhizobium sp. (strain BTAi1 / ATCC BAA-1182)
Length = 415
Score = 108 bits (259), Expect = 2e-22
Identities = 58/191 (30%), Positives = 96/191 (50%), Gaps = 1/191 (0%)
Frame = +2
Query: 233 FKQPAPAEHTGFEYGRSGNPTRNTLEECLAALDGGKYGLTFASXXXXXXXXXXXX-NHGD 409
F+ A + GF YG G PT LE+ +A L+G L S GD
Sbjct: 41 FETRAERVYDGFSYGLYGTPTSRLLEDHVAQLEGAARALVVPSGMAAMTLATMAVCRSGD 100
Query: 410 HIVSSDDVYGGTNRLLRQVIARLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLK 589
++ + +YG ++ + + LGI D + + E T+++W+E+P + +
Sbjct: 101 RVLMPETLYGPARDMILRFLGPLGIAAQTYDPLLDAGIAGLLDERTRLVWVESPGSATFE 160
Query: 590 VVDIEAIVKIARSRGDIIVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAA 769
V D+ AIV +A+ G +V DNT+ + L +PL G DI M +L+K+ GH D++MG+
Sbjct: 161 VQDVPAIVAVAKKVG-ALVAADNTWASHLLFKPLTHGVDISMQALSKHAGGHGDLLMGSL 219
Query: 770 IVNDKAIGXKL 802
V D+A+ +L
Sbjct: 220 AVRDQALFRRL 230
>UniRef50_Q98K64 Cluster: Methionine gamma-lyase; n=13;
Bacteria|Rep: Methionine gamma-lyase - Rhizobium loti
(Mesorhizobium loti)
Length = 427
Score = 107 bits (257), Expect = 3e-22
Identities = 71/197 (36%), Positives = 100/197 (50%), Gaps = 12/197 (6%)
Frame = +2
Query: 236 KQPAPAEHTGFEYGRSGNPTRNTLEECLAALDGGKYGLTFASXXXXXXXXXXX-XNHGDH 412
K+P +G Y R +P +E+ LA +G + F+S GD
Sbjct: 65 KEPPSGTASGLVYSRFNHPNSEIVEDRLAIYEGTDACILFSSGMSAIATTLLAYARPGDV 124
Query: 413 IVSSDDVYGGTNRLLRQVIARLGINTT-FTDFTNIEKVKNAMQE-----NTKMIWIETPT 574
I+ S +YGGT LL + ++ GI F D + + V+ A +I IETP+
Sbjct: 125 ILHSQPLYGGTETLLTRTLSGFGIGAVGFADGVDEKAVRAAADAAVAKGRVSVILIETPS 184
Query: 575 NPLLKVVDIEAIVKIA----RSRGDI-IVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMN 739
NP +VDI + IA S+G I+V DNT L P QRP+ GAD+ +YSLTKY+
Sbjct: 185 NPTNSLVDIALMRMIADEIGASQGSAPIIVCDNTLLGPVFQRPIEHGADVSVYSLTKYVG 244
Query: 740 GHSDVIMGAAIVNDKAI 790
GHSD+I GAA + KA+
Sbjct: 245 GHSDLIAGAA-MGSKAV 260
>UniRef50_Q52811 Cluster: Putative cystathionine beta-lyase; n=35;
Proteobacteria|Rep: Putative cystathionine beta-lyase -
Rhizobium leguminosarum bv. viciae (strain 3841)
Length = 396
Score = 106 bits (255), Expect = 6e-22
Identities = 70/228 (30%), Positives = 107/228 (46%), Gaps = 5/228 (2%)
Frame = +2
Query: 110 MADHGFLKQKPGFATIAIHAGQEPEKWNSAAVVTPIVTSTTFKQP-APAEHTG---FEYG 277
M D L Q G T H G +P ++ + P+V ++T P A A T + YG
Sbjct: 1 MKDKDSLLQNAGINTRLTHIGNDPFDYHGF-INPPVVHASTVLFPNARAMETRTQKYTYG 59
Query: 278 RSGNPTRNTLEECLAALDGGKYGLTFASXXXXXXX-XXXXXNHGDHIVSSDDVYGGTNRL 454
G PT + L E + AL+G + S GDH + D VYG T
Sbjct: 60 TRGTPTTDALCEAIDALEGSAGTILVPSGLAAVTIPFLGFVAAGDHALVVDSVYGPTRHF 119
Query: 455 LRQVIARLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRG 634
++ RLG+ + ++ + NTK++ E P + ++ DI AI +A G
Sbjct: 120 CDTMLKRLGVEVEYYHPEIGAGIETLFRSNTKLVHTEAPGSNTFEMQDIPAISAVAHRHG 179
Query: 635 DIIVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVN 778
+V++DNT+ TP RPL G DI +++ TKY +GHSD+++G N
Sbjct: 180 -AVVMMDNTWATPVYFRPLDHGVDISIHASTKYPSGHSDILLGTVSAN 226
>UniRef50_Q7UQA0 Cluster: Cystathionine gamma-synthase; n=4;
Bacteria|Rep: Cystathionine gamma-synthase -
Rhodopirellula baltica
Length = 434
Score = 106 bits (254), Expect = 7e-22
Identities = 69/236 (29%), Positives = 112/236 (47%), Gaps = 16/236 (6%)
Frame = +2
Query: 104 IGMADHGFLKQKP---GFATIAIHAGQEPEKWN----SAAVVTPIVTSTTFKQPAPAEHT 262
+ M DH P G +T +H +P+ + A+ PI +++TF + +
Sbjct: 26 VEMTDHASRAAGPSSTGLSTQCVHGNIDPDSPSRQHAEGAITAPIYSASTFTFESTDKLL 85
Query: 263 GF--------EYGRSGNPTRNTLEECLAALDGGKYGLTFASXXXXXXXXXXXX-NHGDHI 415
F EYGR GNP +E+ LAALD + + ++S + GD I
Sbjct: 86 DFVEGREQREEYGRYGNPNERLVEQKLAALDNAEDAVVYSSGMAAIVGLLMSRLSSGDEI 145
Query: 416 VSSDDVYGGTNRLLRQVIARLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVV 595
+ D Y + + +A+ G+ T + ++ A+ TKM+ E+PTNP L V
Sbjct: 146 IFFDQCYHRSREFCGKHLAKFGVVTRQVPTGDFAAMEAAITPRTKMLVSESPTNPHLTCV 205
Query: 596 DIEAIVKIARSRGDIIVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMG 763
D+E V + ++ +I ++D T TP RPL G D V +S TKY+ GH+D++ G
Sbjct: 206 DLEQFVALGKAH-EIETLIDATLATPMNVRPLDHGVDYVWHSATKYLGGHNDLLAG 260
>UniRef50_A3X9V5 Cluster: Cystathionine gamma-synthase; n=12;
Rhodobacteraceae|Rep: Cystathionine gamma-synthase -
Roseobacter sp. MED193
Length = 390
Score = 106 bits (254), Expect = 7e-22
Identities = 73/208 (35%), Positives = 104/208 (50%), Gaps = 3/208 (1%)
Frame = +2
Query: 149 ATIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPAPAE--HTGFEYGRSGNPTRNTLEECLA 322
ATIA A + S VV P+ STTF + + + Y RS N EE L+
Sbjct: 19 ATIAAQAAGTIDA-ASGGVVPPLQPSTTFVRDRDYQLVNESNVYLRSHNEAVRLGEEILS 77
Query: 323 ALDGGKYGLTFASXXXXXXXXXXXXNHGDHIVSSDDVYGGTNRLLRQVIARLGINTTFTD 502
L+G + F S +G ++ +Y GT + +R R I D
Sbjct: 78 RLEGAEDTQLFPSGMAAIAAVFRTVPNGGAVIVQSGIYWGTTKWIRDFCTRRDIALHEVD 137
Query: 503 FTNIEKVKNAMQ-ENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYL 679
++I ++ ++++IETP+NP LK VDI+A A++ G +VV D+T TP L
Sbjct: 138 ASDIGALQAVCAVHQAQLLFIETPSNPWLKTVDIKAAKACAQTAGASLVV-DSTAATPLL 196
Query: 680 QRPLXFGADIVMYSLTKYMNGHSDVIMG 763
RPL GADIVM+S TK +NGHSDV+ G
Sbjct: 197 TRPLEMGADIVMHSATKVINGHSDVLGG 224
>UniRef50_A7HB44 Cluster: Cys/Met metabolism
pyridoxal-phosphate-dependent protein; n=2;
Anaeromyxobacter|Rep: Cys/Met metabolism
pyridoxal-phosphate-dependent protein - Anaeromyxobacter
sp. Fw109-5
Length = 363
Score = 105 bits (253), Expect = 1e-21
Identities = 75/217 (34%), Positives = 106/217 (48%)
Frame = +2
Query: 152 TIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPAPAEHTGFEYGRSGNPTRNTLEECLAALD 331
T+A+HA E+ ++ V PI STTF A + G Y R PTR LE L ALD
Sbjct: 14 TLALHADAGVER--TSDVAPPIHVSTTF---AAGDDEGLVYARQDQPTRRRLEAVLGALD 68
Query: 332 GGKYGLTFASXXXXXXXXXXXXNHGDHIVSSDDVYGGTNRLLRQVIARLGINTTFTDFTN 511
GG + +TFAS + + Y T+ + +A GI D
Sbjct: 69 GG-HAVTFASGQAAATAALLHLRPR-RVAIAPGGYHLTHAAI-DALAPCGIEEVPLD--- 122
Query: 512 IEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQRPL 691
A ++W+ETP NP ++ DI + AR+ G +VV D TF TP LQ+PL
Sbjct: 123 ------AEVGAGDVVWLETPKNPTCELQDIASHAARARAAGARLVV-DGTFATPVLQQPL 175
Query: 692 XFGADIVMYSLTKYMNGHSDVIMGAAIVNDKAIGXKL 802
GAD+V +S+TK++ GHSD + G + D+A+ L
Sbjct: 176 ALGADLVYHSMTKFLAGHSDALGGVLVARDQALAEGL 212
>UniRef50_A6GRN0 Cluster: Cystathionine beta-lyase; n=1; Limnobacter
sp. MED105|Rep: Cystathionine beta-lyase - Limnobacter
sp. MED105
Length = 402
Score = 105 bits (252), Expect = 1e-21
Identities = 57/173 (32%), Positives = 88/173 (50%), Gaps = 1/173 (0%)
Frame = +2
Query: 266 FEYGRSGNPTRNTLEECLAALDGGKYGLTFASXXXXXXXXXXX-XNHGDHIVSSDDVYGG 442
+ YG GNPT+ TL + LA ++G + L S GDH + ++VYG
Sbjct: 60 YSYGLHGNPTQYTLAKKLAEIEGATHALVCPSGLTGIALVAQACLKSGDHWLIPENVYGP 119
Query: 443 TNRLLRQVIARLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIA 622
L R + A G+ + D N VK ++ NT ++W E P + +V D++AIV +A
Sbjct: 120 VQALARNLYADYGVEFSEYDPCNAASVKAGLRTNTTLVWTEAPGSLTFEVPDLQAIVALA 179
Query: 623 RSRGDIIVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVND 781
+ G +DNT+ +P G D + +LTKY GH+DV+MGA + N+
Sbjct: 180 KPHG-ARTGIDNTWAAGIAYKPFEHGFDFSVQALTKYQCGHADVLMGAVLSNN 231
>UniRef50_UPI00015BB00D Cluster: cystathionine gamma-synthase; n=1;
Ignicoccus hospitalis KIN4/I|Rep: cystathionine
gamma-synthase - Ignicoccus hospitalis KIN4/I
Length = 387
Score = 105 bits (251), Expect = 2e-21
Identities = 67/219 (30%), Positives = 107/219 (48%), Gaps = 2/219 (0%)
Frame = +2
Query: 152 TIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPAPAEHTGFEYGRSGNPTRNTLEECLAALD 331
T +H G+ + + ++VTPI S +K P + G++Y R+ +PT LE AA++
Sbjct: 14 TRLVHGGEYRDS-ETGSIVTPIFVSAIYKYPEGNPY-GYKYARNSSPTIEALERKAAAVE 71
Query: 332 GGKYGLTFASXXXXXXXXXXXX-NHGDHIVSSDDVYGGTNRLLRQVIARLGINTTFTDFT 508
+ F+S G +V++ D+YG + + GI D
Sbjct: 72 RAAEAVAFSSGMAAISSAAMALLKPGSKLVTTKDIYGTSYEFFTTFLRSYGIEV---DER 128
Query: 509 NI-EKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQR 685
+ E V + +NT ++++ET +NPLL V ++ I K G ++V DNTF TP
Sbjct: 129 GVGEGVLERIDKNTDVVFVETISNPLLIVPPVDEIAKACEEVGAKLIV-DNTFATPINFL 187
Query: 686 PLXFGADIVMYSLTKYMNGHSDVIMGAAIVNDKAIGXKL 802
PL GA V++S +KY+ GH+DV+ G NDK L
Sbjct: 188 PLKVGAYGVVHSASKYLAGHNDVLGGIFATNDKKFALNL 226
>UniRef50_Q9SGU9 Cluster: F1N19.23; n=7; Magnoliophyta|Rep: F1N19.23
- Arabidopsis thaliana (Mouse-ear cress)
Length = 441
Score = 105 bits (251), Expect = 2e-21
Identities = 63/199 (31%), Positives = 105/199 (52%), Gaps = 3/199 (1%)
Frame = +2
Query: 203 VVTPIVTSTTFKQPAPAEHTGFEYGRSGNPTRNTLEECLAALDGGKYGL-TFASXXXXXX 379
V+ P F ++ + Y R NPT L +AAL+G + T +
Sbjct: 72 VMEPDTMRRMFTGELGPDNDFYVYSRHFNPTVLNLSRQMAALEGTQAAYCTSSGMSAISS 131
Query: 380 XXXXXXNHGDHIVSSDDVYGGTNRLLRQVIARL-GINTTFTDFTNIEKVKNAMQEN-TKM 553
+ G H+V++ +YGGT+ LL + R I T+F D T+ V NA+ E T++
Sbjct: 132 VMLQLCSSGGHVVAASTLYGGTHALLSHFLPRTCNITTSFVDITDHGAVANAIVEGRTQV 191
Query: 554 IWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQRPLXFGADIVMYSLTKY 733
++ E+ NP L V DI + ++A +G + VVVDNTF P + P GAD+V++S++K+
Sbjct: 192 LYFESVANPTLTVADIPELSRMAHEKG-VTVVVDNTF-APMVLSPAKLGADVVVHSISKF 249
Query: 734 MNGHSDVIMGAAIVNDKAI 790
++G +D+I GA ++ +
Sbjct: 250 ISGGADIIAGAVCGSENLV 268
>UniRef50_Q98LV9 Cluster: Methionine gamma lyase; n=4;
Rhizobiales|Rep: Methionine gamma lyase - Rhizobium loti
(Mesorhizobium loti)
Length = 395
Score = 104 bits (249), Expect = 3e-21
Identities = 67/225 (29%), Positives = 114/225 (50%), Gaps = 9/225 (4%)
Frame = +2
Query: 116 DHGFLKQKPGFATIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPAPAEHTG-FE------- 271
DH +L + AT+ H E + AVV PI ++ F AE F
Sbjct: 9 DHDYLAEA---ATLLAH----DEPFPGGAVVPPIYQTSLFTFANYAEMADTFAGKRKQPI 61
Query: 272 YGRSGNPTRNTLEECLAALDGGKYGLTFASXXXXXXXXXXXX-NHGDHIVSSDDVYGGTN 448
Y R NPT E +AAL+G + F+S G+ IV+ + YG
Sbjct: 62 YSRGDNPTVMEFEARVAALEGAEAARGFSSGMAAISATVLAFVGAGERIVAVRNCYGDAY 121
Query: 449 RLLRQVIARLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARS 628
RL +++ RL I + D ++ + V A+ K++++E+PT+ + ++ DI + ++A+
Sbjct: 122 RLFERLLPRLNIKVDYVDGSDPDAVAAALP-GAKLLYLESPTSMMFELQDIAHLTRLAKE 180
Query: 629 RGDIIVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMG 763
+G I+ +DN++ TP Q+P+ G D+V++S +KY+ GHSD + G
Sbjct: 181 QG-IVTTIDNSWATPVFQKPISHGVDLVLHSASKYLGGHSDTVAG 224
>UniRef50_P43623 Cluster: Putative cystathionine beta-lyase; n=11;
cellular organisms|Rep: Putative cystathionine
beta-lyase - Saccharomyces cerevisiae (Baker's yeast)
Length = 340
Score = 104 bits (249), Expect = 3e-21
Identities = 67/220 (30%), Positives = 112/220 (50%), Gaps = 4/220 (1%)
Frame = +2
Query: 137 KPGFATIAIHAGQEPEKWNSAAVVTPIVTSTTF---KQPAPAEHTGFEYGRSGNPTRNTL 307
K G T G+ P++ S V P+ +T K + G YG +G+PT + L
Sbjct: 9 KFGITTQLSVIGRNPDE-QSGFVNPPLYKGSTIILKKLSDLEQRKGRFYGTAGSPTIDNL 67
Query: 308 EECLAALDGGKYGLTFASXXXXXXXXXXXXNH-GDHIVSSDDVYGGTNRLLRQVIARLGI 484
E L GG + AS + GDHI+ +D VY T L ++A+ G+
Sbjct: 68 ENAWTHLTGGAGTVLSASGLGSISLALLALSKAGDHILMTDSVYVPTRMLCDGLLAKFGV 127
Query: 485 NTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTF 664
T + D + + ++ ++ NT +I++E+P + ++V DI A+V +A+ G I ++DNT+
Sbjct: 128 ETDYYDPSIGKDIEKLVKPNTTVIFLESPGSGTMEVQDIPALVSVAKKHG-IKTILDNTW 186
Query: 665 LTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVNDK 784
TP G DI + + TKY+ GHSD+++G A N++
Sbjct: 187 ATPLFFDAHAHGIDISVEAGTKYLGGHSDLLIGLASANEE 226
>UniRef50_Q8J0B2 Cluster: Homocysteine synthase-like protein; n=2;
Neotyphodium uncinatum|Rep: Homocysteine synthase-like
protein - Neotyphodium uncinatum
Length = 473
Score = 103 bits (248), Expect = 4e-21
Identities = 68/219 (31%), Positives = 104/219 (47%), Gaps = 10/219 (4%)
Frame = +2
Query: 146 FATIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPAPAEHT--------GFEYGRSGNPTRN 301
F T +H G+ P+ S AV P+ +S F+ + A G Y R NPT N
Sbjct: 25 FETQLLHVGRFPDILGSCAV--PVYSSAAFEFNSVAHGARLLNLTQFGNIYSRFTNPTVN 82
Query: 302 TLEECLAALDGGKYGLTFASXXXXXXXXXXX-XNHGDHIVSSDDVYGGTNRLLRQVIARL 478
L+ LA L+GG AS GD+ VSS V+ GT + ++
Sbjct: 83 VLQNRLAGLEGGVAACAVASGSAAVVVTVMALAGVGDNFVSSFHVHAGTFHQFESLAKQM 142
Query: 479 GINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDN 658
GI F + A+ + TK +W+ET +NP ++D+EA+ + ++G I ++ DN
Sbjct: 143 GIECRFVKSRDPADFAAAIDDKTKFVWLETISNPGNVILDLEAVSMVCHTKG-IPLICDN 201
Query: 659 TF-LTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAI 772
TF Y RP+ G DIV++S TK++ GH + G +
Sbjct: 202 TFGCAGYFCRPINHGVDIVVHSATKWIGGHGTTVGGVIV 240
>UniRef50_Q7M9C8 Cluster: O-ACETYLHOMOSERINE SULFHYDRYLASE; n=1;
Wolinella succinogenes|Rep: O-ACETYLHOMOSERINE
SULFHYDRYLASE - Wolinella succinogenes
Length = 407
Score = 103 bits (247), Expect = 5e-21
Identities = 68/219 (31%), Positives = 105/219 (47%), Gaps = 9/219 (4%)
Frame = +2
Query: 143 GFATIAIHAGQEPEKWNSAAVVTPIVTSTTFK--------QPAPAEHTGFEYGRSGNPTR 298
GF T A+H + + A + TP+ + F+ Q + G Y RS NPT
Sbjct: 3 GFTTRALHVPKAKRDVHGA-LRTPVYDNAAFEFENSDEIAQVSLGRALGHVYSRSSNPTV 61
Query: 299 NTLEECLAALDGGKYGLTFASXXXXXXXXXXX-XNHGDHIVSSDDVYGGTNRLLRQVIAR 475
LE+ L L G L S GD +V++D ++G T L ++ +
Sbjct: 62 EDLEQRLKNLTGALGVLALGSGMAAISTAILTLARAGDSVVTTDRLFGHTLSLFQKTLPS 121
Query: 476 LGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVD 655
GI F D + V++A E TK++++ET +NP L+V D+EA+ K+ ++G I +VVD
Sbjct: 122 FGIEVRFVDVMDSLAVEHACDETTKLLFLETISNPQLQVADLEALSKVVHAKG-IPLVVD 180
Query: 656 NTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAI 772
T PYL G DI + S TK+++G + G I
Sbjct: 181 TTMTPPYLLEAKRLGVDIEVLSSTKFISGGGTSVGGVLI 219
>UniRef50_A0H5P3 Cluster: Cys/Met metabolism
pyridoxal-phosphate-dependent enzymes; n=3; Chloroflexi
(class)|Rep: Cys/Met metabolism
pyridoxal-phosphate-dependent enzymes - Chloroflexus
aggregans DSM 9485
Length = 373
Score = 103 bits (247), Expect = 5e-21
Identities = 72/217 (33%), Positives = 100/217 (46%), Gaps = 5/217 (2%)
Frame = +2
Query: 167 AGQEPEKWNSAAVVTPIVTSTTFKQPAPAEHTGFEYGRS-----GNPTRNTLEECLAALD 331
+G + W AA T ++ P PA + GRS PT LEE + L+
Sbjct: 6 SGLKLASWLVAAGRTVDPGASLNVPPIPASNFILGQGRSYARGDSTPTWEALEEVIGGLE 65
Query: 332 GGKYGLTFASXXXXXXXXXXXXNHGDHIVSSDDVYGGTNRLLRQVIARLGINTTFTDFTN 511
GK + FAS G +V DD Y G L AR + T+
Sbjct: 66 AGK-AVAFASGMAAVAAIFDQLPSGARVVLPDDCYQGVVGLAMAGAARGRWSVQRIALTD 124
Query: 512 IEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQRPL 691
+ A E +IW+E+P+NPLL V D++ I R G I V VDNTF TP Q+PL
Sbjct: 125 TAAWQQACTE-ADLIWLESPSNPLLTVADLDVICAAPRKPGTI-VAVDNTFATPLNQQPL 182
Query: 692 XFGADIVMYSLTKYMNGHSDVIMGAAIVNDKAIGXKL 802
GA + + S TK++ GHSD++ G D+A+ +L
Sbjct: 183 ELGATVSVQSATKFIGGHSDLLAGVVTTRDEALWQQL 219
>UniRef50_UPI0000E0F9F5 Cluster: hypothetical protein OM2255_22574;
n=1; alpha proteobacterium HTCC2255|Rep: hypothetical
protein OM2255_22574 - alpha proteobacterium HTCC2255
Length = 411
Score = 103 bits (246), Expect = 7e-21
Identities = 53/168 (31%), Positives = 92/168 (54%), Gaps = 1/168 (0%)
Frame = +2
Query: 272 YGRSGNPTRNTLEECLAALDGGKYGLTFASXXXXXXXXXXXX-NHGDHIVSSDDVYGGTN 448
Y RS + T +L+ + L+ G +TFA+ +GDHI+ SD ++G T
Sbjct: 56 YSRSSSSTNTSLQNVMNHLEQGIGAVTFATGMAAISTVMLSLLKYGDHIIVSDFLFGNTR 115
Query: 449 RLLRQVIARLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARS 628
+ + +LGI +F D T+++ V NA Q NT +++ E+ +NP+ + D+ AI K +
Sbjct: 116 SFFKH-LQKLGIEVSFVDVTDVQHVVNAKQPNTVLVFCESLSNPMTHIADLSAIGKYCQG 174
Query: 629 RGDIIVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAI 772
+ ++ +VDNT + GA +V+ SLTKY++GH V+ G+ +
Sbjct: 175 Q-QLLYIVDNTMSPSVIFSAKDAGASLVISSLTKYVSGHGQVLGGSVV 221
>UniRef50_Q62JZ5 Cluster: Cystathionine beta-lyase; n=37;
Burkholderiales|Rep: Cystathionine beta-lyase -
Burkholderia mallei (Pseudomonas mallei)
Length = 394
Score = 102 bits (245), Expect = 9e-21
Identities = 57/180 (31%), Positives = 89/180 (49%), Gaps = 1/180 (0%)
Frame = +2
Query: 266 FEYGRSGNPTRNTLEECLAALDGGKYGLTFASXX-XXXXXXXXXXNHGDHIVSSDDVYGG 442
+ YG PT L + LA ++GG + L S GD ++ D+ YG
Sbjct: 57 WRYGLHATPTSLALAQRLAEIEGGAHALLQPSGLCAITNVYFGLVKEGDDVLIPDNAYGP 116
Query: 443 TNRLLRQVIARLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIA 622
+ + GI F D + + +Q NT+++W+E P + ++V D+ AI +A
Sbjct: 117 NGDFGKWLAKDFGITARFYDPMIGAGIADLIQPNTRIVWLEAPGSVTMEVPDVRAITAVA 176
Query: 623 RSRGDIIVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVNDKAIGXKL 802
R+RG I+ +DNT+ +P G DI + +LTKY +G SDV+MGA I D + KL
Sbjct: 177 RARG-IVTAIDNTYSAGLAFKPFEHGVDISVQALTKYQSGGSDVLMGATITADGELHAKL 235
>UniRef50_Q493X0 Cluster: Beta-cystathionase; n=2;
Enterobacteriaceae|Rep: Beta-cystathionase - Blochmannia
pennsylvanicus (strain BPEN)
Length = 395
Score = 102 bits (245), Expect = 9e-21
Identities = 66/224 (29%), Positives = 114/224 (50%), Gaps = 13/224 (5%)
Frame = +2
Query: 146 FATIAIHAGQEPEKWNSAAVVTPIVTSTTF--------KQPAPAEHTGFE---YGRSGNP 292
F T I +G+E +K+ A+ PI+ T+ KQ A H+ + YGR G
Sbjct: 4 FETTLITSGRE-QKYTYGAI-NPIIQRTSSVVFNSIQQKQKAVNNHSTTDKLFYGRYGTI 61
Query: 293 TRNTLEECLAALDGGKYGLTF-ASXXXXXXXXXXXXNHGDHIVSSDDVYGGTNRLLRQVI 469
T +L + + L+ G + + GDHI+ + Y T + R V+
Sbjct: 62 THFSLRQSMTELENGVGCMLYPCGTAAITHTILSFVQPGDHILMTGSAYEPTQKFCRYVL 121
Query: 470 ARLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVK-IARSRGDIIV 646
R+ I+TT+ D + N +Q NT+++ +E+P + ++V D+ +IVK + + + DII+
Sbjct: 122 KRMNIDTTWFDPLIGNNISNLIQHNTRLVILESPGSITMEVQDVPSIVKTVRKKKSDIII 181
Query: 647 VVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVN 778
++DNT+ + L G D+ + S TKY+ GHSD ++G A+ N
Sbjct: 182 LLDNTWSAGVFLKALDIGVDVSLQSGTKYIIGHSDGMIGTAVSN 225
>UniRef50_Q0APK0 Cluster: Cystathionine beta-lyase; n=1; Maricaulis
maris MCS10|Rep: Cystathionine beta-lyase - Maricaulis
maris (strain MCS10)
Length = 385
Score = 102 bits (245), Expect = 9e-21
Identities = 53/178 (29%), Positives = 92/178 (51%), Gaps = 1/178 (0%)
Frame = +2
Query: 272 YGRSGNPTRNTLEECLAALDGGK-YGLTFASXXXXXXXXXXXXNHGDHIVSSDDVYGGTN 448
YGR G T + L L L GG LT + G ++++D +YG
Sbjct: 48 YGRVGLETHDALRGALTELQGGAGCALTSSGLMANTLSILAATEAGGEVLAADCIYGPVR 107
Query: 449 RLLRQVIARLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARS 628
L ++R G+ T F ++ + + + T+ I +E+P + +++ D+ AI K+AR
Sbjct: 108 NFLTTQMSRYGVRTRFFAPQMGAEIGDLITDETQAILLESPGSLTMEMQDVPAIAKVARD 167
Query: 629 RGDIIVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVNDKAIGXKL 802
+G +I ++D+T+ +PL G D + +LTKY+ GHSD++MGA + D A+ +L
Sbjct: 168 KG-VITIIDDTWSAGLTMKPLQLGVDYAVQALTKYVGGHSDLLMGAVVARDDALFQRL 224
>UniRef50_A0JYV8 Cluster: Cystathionine gamma-synthase; n=8;
Actinobacteria (class)|Rep: Cystathionine gamma-synthase
- Arthrobacter sp. (strain FB24)
Length = 387
Score = 102 bits (244), Expect = 1e-20
Identities = 59/174 (33%), Positives = 94/174 (54%), Gaps = 2/174 (1%)
Frame = +2
Query: 248 PAEHTGFEYGRSGNPTRNTLEECLAALDGGKYGLTFASXXXXXXXXXXXXNHGD--HIVS 421
P E Y R NPT EE +A L+G + FA+ H+V+
Sbjct: 53 PLEGQSTVYQRLWNPTVARFEEGVAVLEGAPEAVAFATGMAALSAVLLATVAAGRKHVVA 112
Query: 422 SDDVYGGTNRLLRQVIARLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDI 601
+YGG++ +L + LG TFT + V++A++ +T ++ +ETP NP L++VDI
Sbjct: 113 VRPLYGGSDHILASGV--LGTEVTFT---TADGVRDALRPDTGLVIVETPANPSLELVDI 167
Query: 602 EAIVKIARSRGDIIVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMG 763
++AR + ++VDNTF +P LQ+PL GA +V++S TK++ GH D + G
Sbjct: 168 ---AQLARDADGVPLLVDNTFASPVLQQPLAHGATLVLHSATKFLGGHGDAMGG 218
>UniRef50_Q5FUW3 Cluster: Cystathionine beta-lyase; n=3;
Acetobacteraceae|Rep: Cystathionine beta-lyase -
Gluconobacter oxydans (Gluconobacter suboxydans)
Length = 405
Score = 101 bits (243), Expect = 2e-20
Identities = 58/174 (33%), Positives = 96/174 (55%), Gaps = 2/174 (1%)
Frame = +2
Query: 272 YGRSGNPTRNTLEECLAALDGGKYGLTFASXXXXXXX-XXXXXNHGDHIVSSDDVYGGTN 448
YG G+P ++ LEE L+ ++GG + S GDH++ D VYG T
Sbjct: 69 YGAMGSPIQHQLEEMLSRIEGGTHTQVVGSGLAACALPLLAFLGCGDHLLLPDSVYGPTR 128
Query: 449 RLLRQVIARLGINTTFTDFT-NIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIAR 625
RL ++ R+G+ TT+ T + ++V M+ TK+++ E+P + +V D+ + IA
Sbjct: 129 RLAGTMLQRMGVTTTYYPPTASRDEVLALMRPETKVLFAESPGSHTFEVQDVPMLAGIAH 188
Query: 626 SRGDIIVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVNDKA 787
G ++++ DNT+ Q P G D+ + +L+KY GHSDVIMG+ VN++A
Sbjct: 189 EAGALLML-DNTWGIGVFQ-PFTHGVDVSIQALSKYPAGHSDVIMGSVTVNNEA 240
>UniRef50_Q01X62 Cluster: Cystathionine gamma-synthase; n=1;
Solibacter usitatus Ellin6076|Rep: Cystathionine
gamma-synthase - Solibacter usitatus (strain Ellin6076)
Length = 415
Score = 101 bits (243), Expect = 2e-20
Identities = 61/182 (33%), Positives = 92/182 (50%), Gaps = 5/182 (2%)
Frame = +2
Query: 272 YGRSGNPTRNTLEECLAALDGGK-YGLTFASXXXXXXXXXXXXNHGDH-IVSSDDVYGGT 445
Y R +P LE+ + L+ G Y F S D +V + +YGGT
Sbjct: 72 YSRFSHPNAEILEDQIVPLEAGAAYSAVFNSGMAAIQTAFFAYARPDSTMVYTTPLYGGT 131
Query: 446 NRLLRQVIARLGINTTFTDFTNIEKVKNAMQ--ENTKMIWIETPTNPLLKVVDIEAIVKI 619
L+ + + LG+ E ++ A++ N M+++ETP NP + + DIE +
Sbjct: 132 TGLIHKFMKPLGVTGIPVTSGKTEAIEEAIRGARNCCMVYLETPANPTMIMTDIERAAEA 191
Query: 620 ARSRGDI-IVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVNDKAIGX 796
A D +V+VDNTFL P Q PL GA+I +YS TKY++G+SD++ G AI + I
Sbjct: 192 AAKHPDKPVVMVDNTFLGPSFQHPLLLGANICLYSATKYLSGYSDMLGGVAITDSADIVQ 251
Query: 797 KL 802
KL
Sbjct: 252 KL 253
>UniRef50_A6QZA3 Cluster: Cystathionine gamma-lyase; n=1;
Ajellomyces capsulatus NAm1|Rep: Cystathionine
gamma-lyase - Ajellomyces capsulatus NAm1
Length = 457
Score = 101 bits (243), Expect = 2e-20
Identities = 46/86 (53%), Positives = 64/86 (74%)
Frame = +2
Query: 545 TKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQRPLXFGADIVMYSL 724
T+ I + +P+NP L +VDI I +A G I+VVVDNTFL+PY+Q PL +GADIV++S+
Sbjct: 196 TRHISLRSPSNPTLGLVDIRKIASVAHQHG-IMVVVDNTFLSPYIQNPLDYGADIVVHSV 254
Query: 725 TKYMNGHSDVIMGAAIVNDKAIGXKL 802
TKY+NGHSDV+MG A+ N + +L
Sbjct: 255 TKYINGHSDVLMGVAVFNSPTLHERL 280
Score = 55.6 bits (128), Expect = 1e-06
Identities = 30/69 (43%), Positives = 40/69 (57%), Gaps = 1/69 (1%)
Frame = +2
Query: 146 FATIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPAPAEHTG-FEYGRSGNPTRNTLEECLA 322
F T A+HAG + + AV+ PI STTF Q + G +EY RS NP R+ EE +A
Sbjct: 108 FGTRAVHAGAHVDA-TTGAVIAPISLSTTFAQVGVGKPIGQYEYTRSANPNRDHFEEAVA 166
Query: 323 ALDGGKYGL 349
AL+ +Y L
Sbjct: 167 ALEHARYAL 175
>UniRef50_Q7WM51 Cluster: Cystathionase beta-lyase; n=3;
Proteobacteria|Rep: Cystathionase beta-lyase -
Bordetella bronchiseptica (Alcaligenes bronchisepticus)
Length = 408
Score = 101 bits (242), Expect = 2e-20
Identities = 66/223 (29%), Positives = 110/223 (49%), Gaps = 11/223 (4%)
Frame = +2
Query: 152 TIAIHAGQEPEKWNSAAVVTPIVTSTTF-------KQPAPAEHTG---FEYGRSGNPTRN 301
T +HAG++P A V P+V ++T ++ A +G F YG GNPT
Sbjct: 12 TRLLHAGKKPAYDGGAPVNPPVVRASTVIFDNVAQQRDLRARRSGERLFTYGARGNPTNF 71
Query: 302 TLEECLAALDGGKYGLTFASXXXXXXXXXXXX-NHGDHIVSSDDVYGGTNRLLRQVIARL 478
LE+ ++ L+G F + GDH++ SD VY +L+ +A
Sbjct: 72 ALEDAVSELEGAYRTKLFPTGLAAIAMALLSYLKPGDHLLMSDAVYEPARKLVHSFLAPY 131
Query: 479 GINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDN 658
I TF + V++ ++ T+MI+ E P + + ++ D+ + +IA G ++ DN
Sbjct: 132 QIRCTFFAADGSD-VQDKLEPATRMIYAECPGSLVYEMCDLPRLAEIAHRHGALLAC-DN 189
Query: 659 TFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVNDKA 787
T+ + RPL GAD+ + + TKY++GHSDV+MG + A
Sbjct: 190 TWGSGCQYRPLALGADVSIMAATKYLSGHSDVMMGTVATTEAA 232
>UniRef50_Q9X0Z7 Cluster: Cystathionine gamma-synthase; n=2;
Thermotoga|Rep: Cystathionine gamma-synthase -
Thermotoga maritima
Length = 379
Score = 101 bits (241), Expect = 3e-20
Identities = 53/167 (31%), Positives = 89/167 (53%), Gaps = 1/167 (0%)
Frame = +2
Query: 266 FEYGRSGNPTRNTLEECLAALDGGKYGLTFASXXXXXXXXXXXX-NHGDHIVSSDDVYGG 442
F Y R NPT +E+ LAAL+ + AS + GDH+V D+ Y
Sbjct: 49 FVYKRGSNPTTRLVEKKLAALEECEDARLVASGMSAISLSILHFLSSGDHVVCVDEAYSW 108
Query: 443 TNRLLRQVIARLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIA 622
+ + + I ++ + E++ A+ + TK+I++E+PT+ +KV+DI + + A
Sbjct: 109 AKKFFNYLSKKFDIEVSYVP-PDAERIVEAITKKTKLIYLESPTSMRMKVIDIRKVTEAA 167
Query: 623 RSRGDIIVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMG 763
I V+DNT+ +P Q+P G D+V++S TKY++GH DV+ G
Sbjct: 168 GEL-KIKTVIDNTWASPIFQKPKLLGVDVVVHSATKYISGHGDVMAG 213
>UniRef50_Q45278 Cluster: Aminotransferase and dihydrorhizobitoxine
synthase; n=8; Proteobacteria|Rep: Aminotransferase and
dihydrorhizobitoxine synthase - Bradyrhizobium japonicum
Length = 806
Score = 101 bits (241), Expect = 3e-20
Identities = 73/223 (32%), Positives = 103/223 (46%), Gaps = 12/223 (5%)
Frame = +2
Query: 152 TIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPAPAEHT---------GFEYGRSGNPTRNT 304
T +HAG + A V PI +T ++ H GF Y R NPT
Sbjct: 377 TAVLHAGYRRDPVTKAVAV-PIYQNTAYELDGDLNHIADVYNVKADGFTYTRIINPTTRA 435
Query: 305 LEECLAALDGGKYGLTFASXXXXXXXXXXXXNHG---DHIVSSDDVYGGTNRLLRQVIAR 475
LE+ AA+D G L AS + G D+IV+S +YG T LL + R
Sbjct: 436 LEKRYAAVDMGSDSLAVASGQAATFLAILNLSSGEVGDNIVASPYLYGNTWNLLHNTLKR 495
Query: 476 LGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVD 655
LGI+ D E + A+ + T ++ E +NP L + ++ + +I R G + +VVD
Sbjct: 496 LGISVRTADPRRPETFERAIDDRTICLFGEVISNPCLIPLPVKQLAEIGRKHG-VPLVVD 554
Query: 656 NTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVNDK 784
NT TP + RP GA I YS TKY+ GH + G + N K
Sbjct: 555 NT-TTPLVCRPSDLGAAITTYSATKYICGHGTTLGGLIVDNGK 596
>UniRef50_Q98KA4 Cluster: Probable cystathionine/methionine
gamma-synthase/lyase; n=3; Alphaproteobacteria|Rep:
Probable cystathionine/methionine gamma-synthase/lyase -
Rhizobium loti (Mesorhizobium loti)
Length = 371
Score = 100 bits (240), Expect = 4e-20
Identities = 65/205 (31%), Positives = 96/205 (46%), Gaps = 1/205 (0%)
Frame = +2
Query: 191 NSAAVVTPIVTSTTFKQPAPAEHTGFE-YGRSGNPTRNTLEECLAALDGGKYGLTFASXX 367
N + P+ ++ F P TG + YGR NPT +E L L+ + +
Sbjct: 22 NGDPIPLPLTMASIFH--TPGVETGVDQYGRYDNPTWRAVEHVLGHLEDAQCVSFPSGMG 79
Query: 368 XXXXXXXXXXNHGDHIVSSDDVYGGTNRLLRQVIARLGINTTFTDFTNIEKVKNAMQENT 547
GD ++ D Y T + + + LGI D + +
Sbjct: 80 AISSVFFALLKSGDRVLLPADGYHATRAMAERFLKPLGITC---DTRPTPTFLDGGFKGY 136
Query: 548 KMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQRPLXFGADIVMYSLT 727
++++ETP+NP L + DI AI K +G +VV DNT +TP+ QRPL FGADIV+ + T
Sbjct: 137 SLVFVETPSNPRLDICDISAIAKAVHEQGGALVV-DNTTMTPFGQRPLDFGADIVVSADT 195
Query: 728 KYMNGHSDVIMGAAIVNDKAIGXKL 802
K +NGHSDV+ G D I K+
Sbjct: 196 KAVNGHSDVLFGHVASRDADIISKV 220
>UniRef50_A7S3X8 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 343
Score = 100 bits (240), Expect = 4e-20
Identities = 55/154 (35%), Positives = 84/154 (54%), Gaps = 2/154 (1%)
Frame = +2
Query: 263 GFEYGRSGNPTRNTLEECLAALDGGKYGLTFASXXXXXXXXXXXX-NHGDHIVSSDDVYG 439
G+ Y R NPT + + L AL+GG L F+S GDH+V+ VY
Sbjct: 53 GYLYSRWNNPTVDAAAQTLNALEGGVGTLLFSSGMAAISTALLSLLKAGDHVVAPKIVYS 112
Query: 440 GTNRLLRQVIARLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKI 619
GT LL+ V+ R GI T ++E + A++ +TK+I+ ETP NP + V+D+EA ++
Sbjct: 113 GTLALLQTVLPRYGIEVTLVTGDSMESYQEAVKPSTKVIYGETPCNPTMAVLDLEAFAQL 172
Query: 620 ARSRGD-IIVVVDNTFLTPYLQRPLXFGADIVMY 718
S G+ + +VD+TF +P+ Q PL A +Y
Sbjct: 173 GMSLGEGVATMVDSTFGSPFNQAPLRHAAAAALY 206
>UniRef50_Q1V2M7 Cluster: Cystathionine beta-lyase; n=2; Candidatus
Pelagibacter ubique|Rep: Cystathionine beta-lyase -
Candidatus Pelagibacter ubique HTCC1002
Length = 391
Score = 100 bits (239), Expect = 5e-20
Identities = 55/175 (31%), Positives = 90/175 (51%), Gaps = 1/175 (0%)
Frame = +2
Query: 266 FEYGRSGNPTRNTLEECLAALDGGKYG-LTFASXXXXXXXXXXXXNHGDHIVSSDDVYGG 442
F+YGR G T + L + L ++ + LT GD I+ +D Y
Sbjct: 55 FDYGRQGTSTTHVLSQILKEMEECYHVFLTPTGFGSVFLSIFSIVRPGDEIIVADPTYSP 114
Query: 443 TNRLLRQVIARLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIA 622
T L + + + + F D +++ ++ A+ + TK+I++E P + D+ IV IA
Sbjct: 115 TRILTQDFLKEFNVKSVFYDPHDLKTLEKAITKKTKLIFVENPGSNTFDFQDLGKIVSIA 174
Query: 623 RSRGDIIVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVNDKA 787
+ + I V+DNT+ TPY +P+ G D+ + S TKY +GHSDV+ G+ VN KA
Sbjct: 175 K-KNKIFSVIDNTWGTPYFLKPIKLGFDMSIVSATKYYSGHSDVMGGSLAVNKKA 228
>UniRef50_A6Q4H8 Cluster: O-acetylhomoserine sulfhydrylase; n=3;
Epsilonproteobacteria|Rep: O-acetylhomoserine
sulfhydrylase - Nitratiruptor sp. (strain SB155-2)
Length = 402
Score = 100 bits (239), Expect = 5e-20
Identities = 59/168 (35%), Positives = 87/168 (51%), Gaps = 1/168 (0%)
Frame = +2
Query: 272 YGRSGNPTRNTLEECLAALDGGKYGLTFASXXXXXXXXXXXX-NHGDHIVSSDDVYGGTN 448
Y R GNPT LE LA +D + + AS GD + ++GG+
Sbjct: 53 YARMGNPTNAKLESILAMMDEAEGAVVTASGMGAIAMTVTSMLESGDEVACIGGLFGGSY 112
Query: 449 RLLRQVIARLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARS 628
++ ARLGI F + K+ + TKMI+ E+ NP +++VD EA+ +A+
Sbjct: 113 AFFKETAARLGIKARFYRADELPKISS----KTKMIYCESIGNPNMQIVDFEALGMLAKE 168
Query: 629 RGDIIVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAI 772
+I+ VVDNT LTP L P +GAD+V+YS TK + G S + GA +
Sbjct: 169 H-NILYVVDNT-LTPLLFNPFEYGADLVLYSTTKIIAGFSQALGGAVV 214
>UniRef50_A3SR24 Cluster: Cystathionine gamma-synthase; n=3;
Alphaproteobacteria|Rep: Cystathionine gamma-synthase -
Roseovarius nubinhibens ISM
Length = 386
Score = 100 bits (239), Expect = 5e-20
Identities = 59/198 (29%), Positives = 98/198 (49%), Gaps = 2/198 (1%)
Frame = +2
Query: 194 SAAVVTPIVTSTTFKQPAP-AEHTGFEYGRSGNPTRNTLEECLAALDGGKYGLTFASXXX 370
+ A+V PI S T+ + A + Y R GNPT E +A L+G + F+S
Sbjct: 26 TGAIVPPIQPSATYARDEDYAVRRSYMYRRDGNPTTEQAEAIIADLEGAVDCMLFSSGMS 85
Query: 371 XXXXXXXXXNHGDHIVSSDDVYGGTNRLLRQVIARLGINTTFTDFTNIEKVKNAMQEN-T 547
GDH+V + +Y G + ++ + ++ +++ +++A ++ T
Sbjct: 86 ACMSVIDTLKPGDHVVVPEVMYHGVLQQFQRYAKLHRLEVSYYRPGDLDALRDACRKGKT 145
Query: 548 KMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQRPLXFGADIVMYSLT 727
+++W+E+P NP V DI A ++A + G ++ D T P R L GAD +S T
Sbjct: 146 RLVWVESPNNPDWDVTDIAAAAELAHAAGAKLLT-DCTGTPPCATRALELGADFSFHSAT 204
Query: 728 KYMNGHSDVIMGAAIVND 781
KY+NGHSDV GA V +
Sbjct: 205 KYLNGHSDVTAGALSVRN 222
>UniRef50_Q3IV09 Cluster: O-acetylhomoserine sulfhydrylase; n=1;
Rhodobacter sphaeroides 2.4.1|Rep: O-acetylhomoserine
sulfhydrylase - Rhodobacter sphaeroides (strain ATCC
17023 / 2.4.1 / NCIB 8253 / DSM158)
Length = 440
Score = 99 bits (238), Expect = 6e-20
Identities = 66/198 (33%), Positives = 101/198 (51%), Gaps = 9/198 (4%)
Frame = +2
Query: 200 AVVTPIVTSTTFKQPAPAEHTGFE--------YGRSGNPTRNTLEECLAALDGGKYGLTF 355
++V PI +T F+ P E Y R+ NPT LEE + A++ G+ + F
Sbjct: 26 SLVAPIYQTTAFELPEADEAAALFALEKLTPIYARTDNPTTRVLEERMRAVEQGEACICF 85
Query: 356 ASXXXXXXXXX-XXXNHGDHIVSSDDVYGGTNRLLRQVIARLGINTTFTDFTNIEKVKNA 532
A+ GD+IV+S +++ GT + + LGIN FT+ E +
Sbjct: 86 ATGKAAIVAAICAVTGAGDNIVASRNLFSGTMAMFSATLKNLGINVRFTEQDTAEAFEAL 145
Query: 533 MQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQRPLXFGADIV 712
E TK+ + ET +NPLLKV I ++ + + S G I +V+DNT L L +PL FGA +
Sbjct: 146 SDERTKLWYAETLSNPLLKVFPIASVARRSHSLG-IPLVIDNT-LGVGLCQPLAFGAAVS 203
Query: 713 MYSLTKYMNGHSDVIMGA 766
+ SL+KY+ G + GA
Sbjct: 204 VVSLSKYVAGDGSTMGGA 221
>UniRef50_Q67VG6 Cluster: Putative O-succinylhomoserine
(Thiol)-lyase; n=4; Oryza sativa|Rep: Putative
O-succinylhomoserine (Thiol)-lyase - Oryza sativa subsp.
japonica (Rice)
Length = 425
Score = 99.5 bits (237), Expect = 9e-20
Identities = 49/154 (31%), Positives = 86/154 (55%), Gaps = 2/154 (1%)
Frame = +2
Query: 266 FEYGRSGNPTRNTLEECLAALDGGKYGL-TFASXXXXXXXXXXXXNHGDHIVSSDDVYGG 442
FEY R GNPT LE+ ++A++ + + T + G H+V++ D Y
Sbjct: 77 FEYARYGNPTVEVLEDKISAMEKAEATIVTSSGMNAIVATLLAVVPPGGHVVATTDCYSE 136
Query: 443 TNRLLRQVIARLGINTTFTDFTNIEKVKNAM-QENTKMIWIETPTNPLLKVVDIEAIVKI 619
+R ++++GI TTF D ++E +++ + Q N M + ++ TNP LK VD+ + ++
Sbjct: 137 ARAFIRDRLSKMGIRTTFVDLDDMEALQSVLDQGNVTMFYADSLTNPHLKCVDVRRVAEL 196
Query: 620 ARSRGDIIVVVDNTFLTPYLQRPLXFGADIVMYS 721
RG +V +D+T +P Q+PL GAD+V++S
Sbjct: 197 CHQRG-ALVCIDSTLASPINQKPLTLGADVVLHS 229
>UniRef50_Q6L1U0 Cluster: Cystathionine beta-lyase; n=1; Picrophilus
torridus|Rep: Cystathionine beta-lyase - Picrophilus
torridus
Length = 364
Score = 99.5 bits (237), Expect = 9e-20
Identities = 57/190 (30%), Positives = 96/190 (50%), Gaps = 1/190 (0%)
Frame = +2
Query: 203 VVTPIVTSTTFKQPAPAEHTGFEYGRSGNPTRNTLEECLAALDGGKYGLTFASXXXXXXX 382
+V PI + +++ P + F Y R NPT L + L+ G +F+S
Sbjct: 14 LVFPIYQTGSYEIPGGEK---FRYSREYNPTVENLNNVIKRLEHGDLANSFSSGMGAITT 70
Query: 383 XXXXX-NHGDHIVSSDDVYGGTNRLLRQVIARLGINTTFTDFTNIEKVKNAMQENTKMIW 559
GD V+ D + + + + GI T + E + + + TK+++
Sbjct: 71 TLLSILRPGDEAVTHIDTFARSYHFFSEFLRSFGIKTRISR-PGTENILEEINKRTKLVF 129
Query: 560 IETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMN 739
IET +NP+L+V DI+ I K G +++ D+TF TPY + L GAD+V++S +K+++
Sbjct: 130 IETLSNPVLRVYDIDEISKACSENGALLIC-DSTFATPYNLKTLDHGADVVIHSASKFLS 188
Query: 740 GHSDVIMGAA 769
GH+DVI G A
Sbjct: 189 GHNDVIAGVA 198
>UniRef50_A7H1V2 Cluster: Cystathionine beta-lyase; n=15;
Campylobacter|Rep: Cystathionine beta-lyase -
Campylobacter jejuni subsp. doylei 269.97
Length = 387
Score = 99.1 bits (236), Expect = 1e-19
Identities = 52/172 (30%), Positives = 88/172 (51%), Gaps = 1/172 (0%)
Frame = +2
Query: 272 YGRSGNPTRNTLEECLAALDGGKYGLTFASXXXXXXXXXXXXNHGD-HIVSSDDVYGGTN 448
YG G T LE+ + L+GG F + D H + +D +YG
Sbjct: 55 YGARGTTTNFELEKLICTLEGGYRAQLFPTGLAALAMVLLNYASKDVHFLITDAIYGPVR 114
Query: 449 RLLRQVIARLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARS 628
+ + ++G+ F + V+ ++ NTK+I E+P + L +++D+ + KIA +
Sbjct: 115 TICELFLDKMGVEIDFLK-ADASDVEEKIKPNTKLILCESPGSILYEIIDLPKLCKIAHA 173
Query: 629 RGDIIVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVNDK 784
+I V +DNT+ + Y PL G DI + + TKY++GHSDV MG ++N+K
Sbjct: 174 H-NIPVAIDNTYSSGYFLNPLELGVDISVIAATKYLSGHSDVTMGIVVINEK 224
>UniRef50_Q7W586 Cluster: Cystathionine beta-lyase; n=3;
Bordetella|Rep: Cystathionine beta-lyase - Bordetella
parapertussis
Length = 413
Score = 98.7 bits (235), Expect = 1e-19
Identities = 63/221 (28%), Positives = 107/221 (48%), Gaps = 9/221 (4%)
Frame = +2
Query: 146 FATIAIHAGQEPEKWNSAAVVTPIVTSTT--------FKQPAPAEHTGFEYGRSGNPTRN 301
F T+ H G++P K + V TP+ ++T +K A+ YGR G T
Sbjct: 33 FDTLLTHGGRDP-KAHKGMVNTPVYRTSTVVFESMAEYKATRGAKFDHVRYGRLGTHTVK 91
Query: 302 TLEECLAALDGGKYG-LTFASXXXXXXXXXXXXNHGDHIVSSDDVYGGTNRLLRQVIARL 478
LE +AA++GG LT + G HI+ D+VY +V+A
Sbjct: 92 ELENLVAAIEGGHRAVLTPSGVSAIATTLNTLARPGSHILVPDNVYYPCREFCEKVLAPR 151
Query: 479 GINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDN 658
G+ + + +E++ ++ +T +++ E+P + +++ D I A + G VV DN
Sbjct: 152 GVRVEYYAGSEVERL---VRPDTSVVYCESPGSLTMEMQDFARIAAAAHAVG-AKVVADN 207
Query: 659 TFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVND 781
T+ TP +P G D+ +++ TKY+ GHSDV+MG +D
Sbjct: 208 TWATPVFLQPFEHGIDVSIHAATKYLVGHSDVMMGTVTAHD 248
>UniRef50_Q979X4 Cluster: Cystathionine beta lyase /
O-succinylhomoserine lyase; n=3; Thermoplasma|Rep:
Cystathionine beta lyase / O-succinylhomoserine lyase -
Thermoplasma volcanium
Length = 368
Score = 98.7 bits (235), Expect = 1e-19
Identities = 52/169 (30%), Positives = 90/169 (53%), Gaps = 1/169 (0%)
Frame = +2
Query: 266 FEYGRSGNPTRNTLEECLAALDGGKYGLTFASXXXXXXXXXXX-XNHGDHIVSSDDVYGG 442
+ Y R NPT L L+ L+ + + F+S GD +V DV+G
Sbjct: 32 YRYSRELNPTVEELSRQLSLLENTERSICFSSGMGAITGTILALAKPGDKLVMPTDVFGR 91
Query: 443 TNRLLRQVIARLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIA 622
T + + + GIN F + + + A++E+ +++ E+ +NPLL++ D++ I + A
Sbjct: 92 TYLFAKNFLTKFGINVKFVE-PGTDSLLGAVEEHADIVFFESLSNPLLRLYDVDRICRKA 150
Query: 623 RSRGDIIVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAA 769
G I +VDNT TP L +P +G DI++ SL+K++ GH++ I G+A
Sbjct: 151 SDIG-AITIVDNTLATPILLKPSLYGCDIIIESLSKFIGGHNNAIGGSA 198
>UniRef50_A6W2A4 Cluster: Cystathionine beta-lyase; n=1; Marinomonas
sp. MWYL1|Rep: Cystathionine beta-lyase - Marinomonas
sp. MWYL1
Length = 388
Score = 98.3 bits (234), Expect = 2e-19
Identities = 51/174 (29%), Positives = 90/174 (51%), Gaps = 1/174 (0%)
Frame = +2
Query: 272 YGRSGNPTRNTLEECLAALDGGKYGLTFASXXXXXXXXXXXX-NHGDHIVSSDDVYGGTN 448
YGR G T + L + L+GG F + GDH++ D ++ T
Sbjct: 57 YGRRGTTTAHELAAAINDLEGGDGCFLFPTGIAAIAGAISAYVGAGDHLLVVDTIFSATR 116
Query: 449 RLLRQVIARLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARS 628
+ + R G+ + + N + ++ NTK++ IE+P + +V+D+ + + A
Sbjct: 117 TYCEKQLTRNGVEIEYFPW-NTTDISPYLKSNTKVVMIESPASQTYEVMDLPKLCESAHE 175
Query: 629 RGDIIVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVNDKAI 790
D+IV+ DNT+ + +L +PL G D+ + + TKY+ GH+DV+MGAA+V A+
Sbjct: 176 H-DLIVIADNTYGSSWLYQPLELGCDVSVIAGTKYLGGHADVMMGAAVVKKHAM 228
>UniRef50_Q59829 Cluster: Putative cystathionine gamma-lyase; n=8;
Actinomycetales|Rep: Putative cystathionine gamma-lyase
- Streptomyces coelicolor
Length = 392
Score = 97.5 bits (232), Expect = 3e-19
Identities = 76/214 (35%), Positives = 102/214 (47%), Gaps = 6/214 (2%)
Frame = +2
Query: 140 PGFATIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPAPAEHTG-FEYGRSGNPTRNTLEEC 316
PG T A+ AG PE + V + F P + TG + YGR NPT LE
Sbjct: 21 PGDGTRAVRAGL-PEPVKHEPTLPGPVFAAHFH--LPGDPTGPYTYGRDENPTWTRLESA 77
Query: 317 LAALDG-GKYG---LTFASXXXXXXXXXXXX-NHGDHIVSSDDVYGGTNRLLRQVIARLG 481
+ L+ G+ G L FAS GD V DD Y L+R + G
Sbjct: 78 IGELEAPGEAGVETLVFASGMAAISSVLFSQLRAGDTAVLPDDGYQALP-LVRAQLEAYG 136
Query: 482 INTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNT 661
I T T + + + + K++WIETP+NP L V D+ +V+ A + G +V VDNT
Sbjct: 137 IEVR-TAPTGRDAQLDVL-DGAKLLWIETPSNPGLDVCDVRRLVEAAHA-GGALVAVDNT 193
Query: 662 FLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMG 763
TP QRPL GAD + S TK + GH DV++G
Sbjct: 194 LATPLGQRPLELGADFSVASGTKQLTGHGDVLLG 227
>UniRef50_Q26GX1 Cluster: Cys/Met metabolism PLP-dependent enzyme;
n=2; Flavobacteria|Rep: Cys/Met metabolism PLP-dependent
enzyme - Flavobacteria bacterium BBFL7
Length = 423
Score = 96.7 bits (230), Expect = 6e-19
Identities = 66/188 (35%), Positives = 90/188 (47%), Gaps = 11/188 (5%)
Frame = +2
Query: 248 PAEHTGFEYGRSGNPTRNTLEECLAALDGGKYGLTFASXXXXXXXXXXXX-NHGDHIVSS 424
P E G Y R NP LE L D F S G ++ S
Sbjct: 58 PGEEMGLIYSRINNPDLEILENRLRLWDKADDCAVFESGMSAISTVLMEFLEPGQVLLYS 117
Query: 425 DDVYGGTNRLLRQVIARLGINTT-----FTDFTNIEKVKNA-MQENTKMIWIETPTNPLL 586
YGGT+ + + + GI++ + I+ VK+A + ++ IETP NP
Sbjct: 118 SPTYGGTDHFINHFLPKYGIHSLGFKSGMSKEEIIKLVKDAGYADKIALMHIETPANPTN 177
Query: 587 KVVDIEAIVKIAR--SRGD--IIVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDV 754
++DIE +IA S D ++V VDNT++ P Q PL GADIVMYS TKY+ GHSD+
Sbjct: 178 ALIDIEMCREIADHFSTSDKKVLVGVDNTYMGPLWQHPLQLGADIVMYSATKYIGGHSDL 237
Query: 755 IMGAAIVN 778
I GA + N
Sbjct: 238 IAGAVLGN 245
>UniRef50_Q1GVW8 Cluster: Cystathionine gamma-lyase; n=15;
Bacteria|Rep: Cystathionine gamma-lyase - Sphingopyxis
alaskensis (Sphingomonas alaskensis)
Length = 430
Score = 96.7 bits (230), Expect = 6e-19
Identities = 70/211 (33%), Positives = 104/211 (49%), Gaps = 19/211 (9%)
Frame = +2
Query: 188 WNSAAVVTPIVTSTTFKQPAPAEHTGFEYGRSGNPTRNTLEECLAALDGGKYGLTFASXX 367
+ SAA T K+ PA+ G Y R P + LE+ LA DG L F+S
Sbjct: 51 FESAAAGKRFFEHITGKREGPAD--GLVYSRFNGPNQEILEDRLAVWDGADDSLVFSSGM 108
Query: 368 XXXXXXXXXX-NHGDHIVSSDDVYGGTNRLLRQVIARLGINTTFTDFT------NIEKVK 526
D IV S +Y T L+ ++++R G++ F DF +I+ +
Sbjct: 109 SAIATLLLALVGQNDVIVHSGPLYAATETLIARILSRFGVS--FVDFPAGASRDDIDVIL 166
Query: 527 N-----AMQENTK--MIWIETPTNPLLKVVDIEAIVKIARSRG-----DIIVVVDNTFLT 670
A Q+ K ++++E+P NP +VD+EA V+ AR + +DNTFL
Sbjct: 167 ARAQALASQKGGKVALVYLESPANPTNALVDVEA-VRAARDTAFPGEQKPAIAIDNTFLG 225
Query: 671 PYLQRPLXFGADIVMYSLTKYMNGHSDVIMG 763
P Q+PL GA++V+YSLTKY GHSD++ G
Sbjct: 226 PLWQQPLKQGAELVIYSLTKYAGGHSDLVAG 256
>UniRef50_Q11MH2 Cluster: Cys/Met metabolism
pyridoxal-phosphate-dependent enzymes; n=1;
Mesorhizobium sp. BNC1|Rep: Cys/Met metabolism
pyridoxal-phosphate-dependent enzymes - Mesorhizobium
sp. (strain BNC1)
Length = 407
Score = 96.7 bits (230), Expect = 6e-19
Identities = 59/217 (27%), Positives = 104/217 (47%), Gaps = 1/217 (0%)
Frame = +2
Query: 143 GFATIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPAPAEHTGFEYGRSGNPTRNTLEECLA 322
GFA++A+ + ++ +V P +S F+ + G+ YG G PT TLE ++
Sbjct: 17 GFASLAVPVTR------ASTIVFP--SSDAFESRYEHFYDGYTYGLYGTPTSRTLEARIS 68
Query: 323 ALDGGKYGLTFASXXXXXXXXXXXX-NHGDHIVSSDDVYGGTNRLLRQVIARLGINTTFT 499
L + L S GD ++ + YG T +++A G+
Sbjct: 69 ELYAADHCLCLPSGQSATVLALSALLKAGDRVLVTTSAYGSTRTFCTEMLAAFGVEVALY 128
Query: 500 DFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYL 679
D + + + T+M+ +E+P + +++ DI AI A + G V+ DNT+ +
Sbjct: 129 DPGVASGIGAFLDDRTRMVVVESPGSNTMEIQDIPAIAHAAHAWGGC-VLADNTWASALC 187
Query: 680 QRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVNDKAI 790
PL GADI M +L+K+ GH+DV++GA + D+A+
Sbjct: 188 CNPLDLGADIAMEALSKHAGGHADVLLGALVTRDEAL 224
>UniRef50_A3K0Q5 Cluster: O-succinylhomoserine sulfhydrylase; n=3;
Rhodobacteraceae|Rep: O-succinylhomoserine sulfhydrylase
- Sagittula stellata E-37
Length = 391
Score = 96.7 bits (230), Expect = 6e-19
Identities = 58/212 (27%), Positives = 103/212 (48%), Gaps = 8/212 (3%)
Frame = +2
Query: 152 TIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPAPAE-------HTGFEYGRSGNPTRNTLE 310
T +H G + +W + + ++ AE F Y R GNPT E
Sbjct: 7 TRLVHGGTKRSQWGEMSEAIFLTQGFVYETAEAAEARFVKAGDDEFIYARYGNPTMRMFE 66
Query: 311 ECLAALDGGKYGLTFASXXXXXXXXXXXXNH-GDHIVSSDDVYGGTNRLLRQVIARLGIN 487
E L+ G + G AS GDH+V+S ++G +L V+AR G+
Sbjct: 67 ERLSGYLGFEDGFACASGMAAVNGALMALTKAGDHVVASRALFGSCLYVLEDVLARFGVE 126
Query: 488 TTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFL 667
T D T+ + A++++T+++++E+ +NP L+V+D+ + K+A ++G +V+ D+
Sbjct: 127 VTLIDGTDNAAWEAAVRDDTRLVFLESISNPTLEVIDLAHVCKVAHAKG-ALVLCDDAMA 185
Query: 668 TPYLQRPLXFGADIVMYSLTKYMNGHSDVIMG 763
TP GADI + S TK+++G ++ G
Sbjct: 186 TPVYSYARACGADISIVSTTKHVDGQGRMLGG 217
>UniRef50_A2Y9X5 Cluster: Putative uncharacterized protein; n=1;
Oryza sativa (indica cultivar-group)|Rep: Putative
uncharacterized protein - Oryza sativa subsp. indica
(Rice)
Length = 408
Score = 96.7 bits (230), Expect = 6e-19
Identities = 46/101 (45%), Positives = 68/101 (67%)
Frame = +2
Query: 500 DFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYL 679
D T I +V +A+ TK++W+E+PTNP L++ DI+ I +IA G +V+VDN+ ++P L
Sbjct: 177 DTTKISEVTSAIGPLTKLVWLESPTNPRLQITDIKKIAEIAHYHG-ALVLVDNSIMSPVL 235
Query: 680 QRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVNDKAIGXKL 802
RPL GADIVM+S TK++ GHSD++ G V + G L
Sbjct: 236 SRPLELGADIVMHSATKFIAGHSDLMAGILAVKGERDGPPL 276
Score = 49.2 bits (112), Expect = 1e-04
Identities = 25/76 (32%), Positives = 41/76 (53%)
Frame = +2
Query: 134 QKPGFATIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPAPAEHTGFEYGRSGNPTRNTLEE 313
++P ATI + + S + TP+ + TFKQP+ ++ ++Y RSGNPTR+ L+
Sbjct: 94 KEPSVATILTSFENSFDGFGSMS--TPLYQTATFKQPSATDNGPYDYTRSGNPTRDVLQS 151
Query: 314 CLAALDGGKYGLTFAS 361
+A L+ F S
Sbjct: 152 LMAKLEKADQAFCFTS 167
>UniRef50_A4S3Y0 Cluster: Putative 2nd cystathione gamma synthase;
n=1; Ostreococcus lucimarinus CCE9901|Rep: Putative 2nd
cystathione gamma synthase - Ostreococcus lucimarinus
CCE9901
Length = 386
Score = 96.3 bits (229), Expect = 8e-19
Identities = 70/229 (30%), Positives = 101/229 (44%), Gaps = 5/229 (2%)
Frame = +2
Query: 110 MADHGFLKQKPGFATIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPAPAEHTGFE-----Y 274
M DHG L + A A +P + +V+ PI STT+ + E F Y
Sbjct: 1 MLDHGTLLVRG-----AADAADDPTR----SVIQPIYPSTTYARDDAHELPRFRDRTLCY 51
Query: 275 GRSGNPTRNTLEECLAALDGGKYGLTFASXXXXXXXXXXXXNHGDHIVSSDDVYGGTNRL 454
R NP+ E L L+ G F+S G SS +R
Sbjct: 52 ARPDNPSVRACERTLRDLERGSDCALFSSGMAAVNAVLEGAVRGTSDASSFAC--SPSRG 109
Query: 455 LRQVIARLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRG 634
V AR+ +E + ++W+E+P NP V+D+E +V +AR+
Sbjct: 110 YFAVRARIREWCAARGVEVVEYDPDVPGRKAALVWVESPANPTWDVMDLEQVVAVARACD 169
Query: 635 DIIVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVND 781
V VD+T LTP +PL FG D+VM+S TKY+NGH DV+ GA + +
Sbjct: 170 AGCVCVDSTVLTPICTKPLSFGVDVVMHSATKYLNGHGDVVAGALVTRE 218
>UniRef50_Q4Q511 Cluster: Cystathionine beta-lyase, putative; n=3;
Leishmania|Rep: Cystathionine beta-lyase, putative -
Leishmania major
Length = 399
Score = 96.3 bits (229), Expect = 8e-19
Identities = 64/216 (29%), Positives = 107/216 (49%), Gaps = 9/216 (4%)
Frame = +2
Query: 164 HAGQEP-EKWNSAAVVTPIVTSTT--FKQ--PAPAEHTGFEYGRSGNPTRNTLEECLAAL 328
H G+ P E+W + PI +T +K A + + YG +GNPT L+ AL
Sbjct: 17 HVGRNPDEQWGF--INCPIYRGSTVLYKSINDALKLRSVYWYGTAGNPTVTNLQNAWTAL 74
Query: 329 DGGKYGLTFASXXXXXXXXX-XXXNHGDHIVSSDDVYGGTNRLLRQVIARLGINTTFTD- 502
GG + +S N GD+I+ +D VY T L + GI TT+ D
Sbjct: 75 TGGAGSVVVSSGMQAIAYALLATANSGDNILVADAVYLPTRNLCDHFLVTKGITTTYYDP 134
Query: 503 FTNIEKVKNAMQE--NTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPY 676
++++ + + NT +I++E+P + ++ D+ I +AR ++ ++DNT+ TP
Sbjct: 135 CITADELRELLHQKPNTTVIFMESPGSQTFEIQDVPMICAVAREF-NVTTIIDNTWATPI 193
Query: 677 LQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVNDK 784
L G DI + + TKY+ GHSD+++G N+K
Sbjct: 194 FFDALGIGCDISVEAGTKYVGGHSDLLLGLISANEK 229
>UniRef50_A3PXR9 Cluster: Cys/Met metabolism
pyridoxal-phosphate-dependent enzymes; n=7;
Actinomycetales|Rep: Cys/Met metabolism
pyridoxal-phosphate-dependent enzymes - Mycobacterium
sp. (strain JLS)
Length = 367
Score = 95.1 bits (226), Expect = 2e-18
Identities = 63/185 (34%), Positives = 88/185 (47%), Gaps = 1/185 (0%)
Frame = +2
Query: 212 PIVTSTTFKQPAPAEHTGFEYGRSGNPTRNTLEECLAALDGGKYGLTFASXXXXXXXXXX 391
P+ S P A+ YGRS NPT LE LA L+G L F S
Sbjct: 29 PVPVSAYHLSPDEAQPLD-TYGRSSNPTWRRLEAALAELEGASAALAFGSGMAAITSALR 87
Query: 392 X-XNHGDHIVSSDDVYGGTNRLLRQVIARLGINTTFTDFTNIEKVKNAMQENTKMIWIET 568
G+ +V D Y R + +A G+ T + E + A + ++ ET
Sbjct: 88 VLTGPGERLVVPADGYYQVRRYAAEYLAPQGV--TVLEVATAEMCEAAADAD--VVLAET 143
Query: 569 PTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHS 748
P NP L+VVD+ + R RG ++V DNT TP Q+PL GA++V+ S TK ++GHS
Sbjct: 144 PANPGLEVVDLHRLAMTCRRRGATLIV-DNTTATPLGQQPLSLGANLVVASATKALSGHS 202
Query: 749 DVIMG 763
D+I G
Sbjct: 203 DLIAG 207
>UniRef50_Q3A8R5 Cluster: O-acetylhomoserine/O-acetylserine
sulfhydrylase; n=1; Carboxydothermus hydrogenoformans
Z-2901|Rep: O-acetylhomoserine/O-acetylserine
sulfhydrylase - Carboxydothermus hydrogenoformans
(strain Z-2901 / DSM 6008)
Length = 400
Score = 94.7 bits (225), Expect = 2e-18
Identities = 56/171 (32%), Positives = 88/171 (51%), Gaps = 1/171 (0%)
Frame = +2
Query: 263 GFEYGRSGNPTRNTLEECLAALDGGKYGL-TFASXXXXXXXXXXXXNHGDHIVSSDDVYG 439
GF Y R NPT LEE +A L+GG T + G + ++G
Sbjct: 39 GFFYSRVANPTVAALEEKVARLEGGVMATATSSGMAAIALTFMAFAQPGAEFLVCAGLFG 98
Query: 440 GTNRLLRQVIARLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKI 619
GT LL+ + GI + E VK + +T+++++E+ NP LK+ D +V +
Sbjct: 99 GTLNLLKNLTKTCGITYKLLPAPDPELVKKHLTSSTRLVFVESIGNPTLKIPDFAGLVSL 158
Query: 620 ARSRGDIIVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAI 772
++ I +VVDNT + P L +PL GA+IV++SL+KY++G VI G +
Sbjct: 159 LKAH-KIPLVVDNT-VAPLLVKPLSLGANIVIHSLSKYISGQGTVIGGCIV 207
>UniRef50_A6GJL1 Cluster: Methionine gamma-lyase; n=1; Plesiocystis
pacifica SIR-1|Rep: Methionine gamma-lyase -
Plesiocystis pacifica SIR-1
Length = 399
Score = 93.9 bits (223), Expect = 4e-18
Identities = 70/236 (29%), Positives = 106/236 (44%), Gaps = 16/236 (6%)
Frame = +2
Query: 128 LKQKPGFATIAIHAGQEPEKWNSAAVVTPIVT-STTFKQPAP---AEHTGFE------YG 277
+ ++P +T+ IH G E + P + STTF P A TG YG
Sbjct: 1 MARRPALSTMLIHPGHADETAATRHGSAPAIERSTTFPLDQPRVDAMVTGQGLRQADVYG 60
Query: 278 RSGNPTRNTLEECLAALDGGKY-GLTFASXXXXXXXXXXXXNHGDHIVSSDDVYGGTNRL 454
R G T + +A L+G + LT + G + ++ VYGGT +
Sbjct: 61 RFGTSTGRVAADLIARLEGAEACALTASGMAAITTTLTTLVPAGGRVACAEVVYGGTESV 120
Query: 455 LRQVIARLGINTTFTDFTNIEKVKNAM-----QENTKMIWIETPTNPLLKVVDIEAIVKI 619
LR + G+ D E + + Q ++W E+ NPL+++ I AI ++
Sbjct: 121 LRHELEPRGVRCDRFDARRPETLAPLLDPPPGQAKPDLVWCESIANPLMRIGQISAIARL 180
Query: 620 ARSRGDIIVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVNDKA 787
G + + VD TF Q PL GA +V++S TK +NGHSDV+ G AI +D A
Sbjct: 181 CADAG-VPLGVDATFAGGMAQNPLALGASVVVHSATKVLNGHSDVVAG-AIASDAA 234
>UniRef50_Q0C2A8 Cluster: Cystathionine beta-lyase; n=1; Hyphomonas
neptunium ATCC 15444|Rep: Cystathionine beta-lyase -
Hyphomonas neptunium (strain ATCC 15444)
Length = 389
Score = 92.7 bits (220), Expect = 1e-17
Identities = 57/210 (27%), Positives = 99/210 (47%), Gaps = 3/210 (1%)
Frame = +2
Query: 182 EKWNSAAVVTPIVTSTT--FKQPAPAEHTGFEYGRSGNPTRNTLEECLAALDGGKYG-LT 352
E+ V P+ ++T F+ A YGR G LE + L+G K+ L
Sbjct: 19 ERLGRVTVNPPVERASTVLFRTEAQLYGPKPTYGRMGLTVHRELEAAMCILEGAKHTRLA 78
Query: 353 FASXXXXXXXXXXXXNHGDHIVSSDDVYGGTNRLLRQVIARLGINTTFTDFTNIEKVKNA 532
G H + +D YG T R + + +G+ D ++
Sbjct: 79 SNGLQACALAIASVVEAGGHFLFTDSAYGPTARFCEKRLKAMGVEAERFDPRMGAGIERL 138
Query: 533 MQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQRPLXFGADIV 712
++NT+ I +E+P + ++ D+ A+ ++A++RG I +V DNT+ +PL GAD+
Sbjct: 139 FRDNTQAILVESPGSLTFEISDLPAMAQVAKARG-IRIVCDNTWGAGLHYKPLALGADLS 197
Query: 713 MYSLTKYMNGHSDVIMGAAIVNDKAIGXKL 802
+ +LTKY+ GHSD GA + N+ ++ K+
Sbjct: 198 VQALTKYVVGHSDAFGGAVMTNELSLANKV 227
>UniRef50_P44527 Cluster: Cystathionine beta-lyase; n=78;
Gammaproteobacteria|Rep: Cystathionine beta-lyase -
Haemophilus influenzae
Length = 396
Score = 92.7 bits (220), Expect = 1e-17
Identities = 50/171 (29%), Positives = 88/171 (51%), Gaps = 2/171 (1%)
Frame = +2
Query: 272 YGRSGNPTRNTLEECLAALDGGKYGLTF-ASXXXXXXXXXXXXNHGDHIVSSDDVYGGTN 448
YGR G T L++ + ++GG + GDH++ S Y T
Sbjct: 57 YGRRGTLTHFALQDLMCEMEGGAGCYLYPCGTAAVTNSILSFVKTGDHVLMSGAAYEPTQ 116
Query: 449 RLLRQVIARLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARS 628
V+ ++ I+ T+ D E + +Q NTK++++E P++ +++ DI IVK AR
Sbjct: 117 YFCNIVLKKMQIDITYYDPLIGEDIATLIQPNTKVLFLEAPSSITMEIPDIPTIVKAARK 176
Query: 629 -RGDIIVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVN 778
+I++++DNT+ L + L DI + + TKY+ GHSD+++G A+ N
Sbjct: 177 VNPNIVIMIDNTWSAGVLFKALEHDIDISIQAGTKYLVGHSDIMIGTAVAN 227
>UniRef50_Q5LN68 Cluster: Cys/Met metabolism PLP-dependent enzyme
family protein; n=2; Rhodobacterales|Rep: Cys/Met
metabolism PLP-dependent enzyme family protein -
Silicibacter pomeroyi
Length = 371
Score = 92.3 bits (219), Expect = 1e-17
Identities = 58/196 (29%), Positives = 91/196 (46%)
Frame = +2
Query: 203 VVTPIVTSTTFKQPAPAEHTGFEYGRSGNPTRNTLEECLAALDGGKYGLTFASXXXXXXX 382
V P+V S+ + P + + YGR+ NPT LE L L+G + +
Sbjct: 28 VALPLVQSSMYHLPGTPDGSN-SYGRADNPTWVALEHALEHLEGASCRVFPSGMGAISAA 86
Query: 383 XXXXXNHGDHIVSSDDVYGGTNRLLRQVIARLGINTTFTDFTNIEKVKNAMQENTKMIWI 562
G ++ D Y T L + + LG+N + ++++
Sbjct: 87 LFATLQAGQRLLIPADGYYVTRLLADRYLRPLGVNVEERPTAGFAEGGFG---GFDVVFL 143
Query: 563 ETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNG 742
ETP+NP L ++D+ A+ + R+ G I + DNT +TP QRPL G DIV+ S TK M G
Sbjct: 144 ETPSNPGLDLIDLAAVARAVRAAGGI-TICDNTTMTPLGQRPLDLGIDIVVASDTKAMGG 202
Query: 743 HSDVIMGAAIVNDKAI 790
HSD+++G D +
Sbjct: 203 HSDLLLGHVASRDAGL 218
>UniRef50_Q6N7A9 Cluster: Putative homocysteine synthase; n=1;
Rhodopseudomonas palustris|Rep: Putative homocysteine
synthase - Rhodopseudomonas palustris
Length = 397
Score = 91.9 bits (218), Expect = 2e-17
Identities = 65/219 (29%), Positives = 104/219 (47%), Gaps = 10/219 (4%)
Frame = +2
Query: 152 TIAIHAGQEPEKWNSAAVVTPIVTSTTF--------KQPAPAEHTGFEYGRSGNPTRNTL 307
T+A+H G + AVV PI +T++ ++ E G+ Y R+ NPTR L
Sbjct: 11 TLAVHGGSFRSDPVTGAVVPPIYLTTSYQFQDTEHARRIFALEEIGYTYTRTVNPTREFL 70
Query: 308 EECLAALDGGKYGLTFASXXXXXXXXXXXXNH-GDHIVSSDDVYGGTNRLLRQVIARLGI 484
E ++AL+GG L A+ H GD++V S D+ G N L + + GI
Sbjct: 71 ERRVSALEGGVGALALATGESASLYALLNIAHSGDNVVLSPDIVTGRNAGLVASLRQFGI 130
Query: 485 NTTFTDFT-NIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNT 661
+ F T + E A T+ ++E+ + P L+ + + A+ G + ++VDNT
Sbjct: 131 DVRFAAETGSAESFATATDARTRAYYVESLSVPQLRAFPLAGAAEAAQQAG-VPLIVDNT 189
Query: 662 FLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVN 778
P RP GA +V+YS +Y+ GH D G I++
Sbjct: 190 -AQPLSVRPFEHGAALVIYSAAEYLGGH-DGAQGGLIID 226
>UniRef50_Q13Z52 Cluster: Cystathionine beta-lyase; n=2;
Burkholderia|Rep: Cystathionine beta-lyase -
Burkholderia xenovorans (strain LB400)
Length = 394
Score = 91.9 bits (218), Expect = 2e-17
Identities = 55/181 (30%), Positives = 92/181 (50%), Gaps = 2/181 (1%)
Frame = +2
Query: 266 FEYGRSGNPTRNTLEECLAALDGGKYGLTFASXXXXXXXXXXXX-NHGDHIVSSDDVYGG 442
+ YG PT L + LA ++GG + L S GD ++ D+VY
Sbjct: 57 WRYGLHATPTSLALAQRLATIEGGNHALLQPSGLSSISNVYFGLVKAGDDVLIPDNVYS- 115
Query: 443 TNRLLRQVIAR-LGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKI 619
NR +AR G++ + + + + ++ NT++IW+E P + ++V D+ AI +
Sbjct: 116 PNRDHGDWLARDFGVSVRYYNPMIGAGIADLIRPNTRLIWLEAPGSVTMEVADVPAITAV 175
Query: 620 ARSRGDIIVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVNDKAIGXK 799
AR+ +++ +DNT+ RP G DI + +LTKY +G DV+MGA I D+ + K
Sbjct: 176 ARAH-NVVTAIDNTWSAGLGFRPFDHGVDISVQALTKYQSGGGDVLMGATITVDRELHLK 234
Query: 800 L 802
L
Sbjct: 235 L 235
>UniRef50_A3VUE2 Cluster: Cystathionine beta-lyase; n=1;
Parvularcula bermudensis HTCC2503|Rep: Cystathionine
beta-lyase - Parvularcula bermudensis HTCC2503
Length = 381
Score = 91.5 bits (217), Expect = 2e-17
Identities = 57/174 (32%), Positives = 86/174 (49%), Gaps = 2/174 (1%)
Frame = +2
Query: 251 AEHTGFEYGRSGNPTRNTLEECLAALDGG-KYGLTFASXXXXXXXXXXXXNHGDHIVSSD 427
A + YGR+G PT LEE L L+G LT + G H++ +D
Sbjct: 40 ANRPPWHYGRTGTPTHRALEESLCDLEGADNVVLTGSGLEACTLAILSCVTAGGHVLVTD 99
Query: 428 DVYGGTNRLLRQVIARLGINTTFTD-FTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIE 604
Y T ++ I TT+ D E++ + T++I+ E+P + +V D+
Sbjct: 100 SAYEPTRTFCDGLLRGFDIETTYFDPQAGREEIAALCRPTTQLIFCESPGSLTFEVQDLP 159
Query: 605 AIVKIARSRGDIIVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGA 766
AIV A G++ V VDNT+ L RPL G I + +LTKY+ GHSD+++GA
Sbjct: 160 AIVAGA---GEVPVAVDNTYGAGVLLRPLELGCAISVQALTKYVGGHSDLLLGA 210
>UniRef50_Q1DAY0 Cluster: Cys/Met metabolism PLP-dependent enzyme;
n=2; Cystobacterineae|Rep: Cys/Met metabolism
PLP-dependent enzyme - Myxococcus xanthus (strain DK
1622)
Length = 394
Score = 91.1 bits (216), Expect = 3e-17
Identities = 63/212 (29%), Positives = 96/212 (45%), Gaps = 8/212 (3%)
Frame = +2
Query: 152 TIAIHAGQEPEKWNSAAVVTPIVTSTT--FKQP----APAEHTGFEYGRSGNPTRNTLEE 313
T+A+HAG + V PI + F + + + Y R P LEE
Sbjct: 7 TVAVHAGTRLAGSKAVPVSPPIYPAAVNWFDSSDDLDSALDGKDYAYARISAPNTTLLEE 66
Query: 314 CLAALDGGKYGLTFASXXXXXXXXXXXXNH--GDHIVSSDDVYGGTNRLLRQVIARLGIN 487
+AAL+G + + +AS GD +V D YG T L + + A LG+
Sbjct: 67 AVAALEGAEDCVAYASGMAALRSVFEAQGFRAGDKLVMPADGYGVTRALYKSLCATLGVE 126
Query: 488 TTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFL 667
T+ E + +M+ E+ +NPLL+V D+ + + + G VV D TF
Sbjct: 127 LHAFLMTDPEVPERIRALKPRMVLAESISNPLLRVPDLRVLARACQDVGATFVV-DGTFP 185
Query: 668 TPYLQRPLXFGADIVMYSLTKYMNGHSDVIMG 763
+P QR L GAD + S +K++NGHSD + G
Sbjct: 186 SPVGQRALALGADYAVQSTSKWLNGHSDALGG 217
>UniRef50_Q6MN74 Cluster: Cys/Met metabolism lyase; n=1;
Bdellovibrio bacteriovorus|Rep: Cys/Met metabolism lyase
- Bdellovibrio bacteriovorus
Length = 426
Score = 89.8 bits (213), Expect = 7e-17
Identities = 59/191 (30%), Positives = 98/191 (51%), Gaps = 9/191 (4%)
Frame = +2
Query: 227 TTFKQPAPAEHTGFEYGRSGNPTRNTLEECLAALDGGKYGLTFASXXXXXXXXXXXX-NH 403
+TF E + Y R PT LE+ LA L+ G+ +TF S +
Sbjct: 55 STFGAQKGEEKPIWIYDRLEEPTTKMLEDQLALLEKGECAVTFGSGMGAIASTLMSLLSS 114
Query: 404 GDHIVSSDDVYGGTNRLLRQVIARLGINTTFTDFTNIEKVKNAMQENT-KMIWIETPTNP 580
G +++ +YG T LL + RL I+T D + + ++ + + ++++ E+ +NP
Sbjct: 115 GQKVIAHKTLYGCTYSLLTNWLPRLNISTHLMDVNDFKNLELQLADPAARVVYFESVSNP 174
Query: 581 LLKVVDIE---AIVKIA-RSRG---DIIVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMN 739
+L++ D++ A+VK A + RG I VVDNTF TP+ RP+ + D V+ SLTK ++
Sbjct: 175 ILEIADLQKITALVKAANKKRGKDNQIYTVVDNTFATPWALRPVEWNVDFVIQSLTKNIS 234
Query: 740 GHSDVIMGAAI 772
G + GA I
Sbjct: 235 GFGTEMGGAVI 245
>UniRef50_Q7X1G1 Cluster: Lfe147p1; n=2; Leptospirillum|Rep:
Lfe147p1 - Leptospirillum ferrooxidans
Length = 321
Score = 86.6 bits (205), Expect = 6e-16
Identities = 45/114 (39%), Positives = 68/114 (59%), Gaps = 3/114 (2%)
Frame = +2
Query: 431 VYGGTNRLLRQVIARLGINTTFTDFTNI---EKVKNAMQENTKMIWIETPTNPLLKVVDI 601
+YGGT + Q + G + D E++ + +T I+ ETP+NP++ V+D+
Sbjct: 37 LYGGTRAFIEQYLIPSGCLIHWFDPREEGWDEELSRRLSPDTGAIFAETPSNPVMTVIDL 96
Query: 602 EAIVKIARSRGDIIVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMG 763
E + A+ G +VV DNTF TP LQ+PL GADIV++S TKY+ GH D++ G
Sbjct: 97 EKLSSAAKKVGAPLVV-DNTFATPILQKPLVLGADIVVHSATKYLGGHGDLLGG 149
>UniRef50_Q1NS60 Cluster: O-acetylhomoserine
aminocarboxypropyltransferase; n=3; Bacteria|Rep:
O-acetylhomoserine aminocarboxypropyltransferase - delta
proteobacterium MLMS-1
Length = 415
Score = 86.6 bits (205), Expect = 6e-16
Identities = 55/168 (32%), Positives = 85/168 (50%), Gaps = 1/168 (0%)
Frame = +2
Query: 272 YGRSGNPTRNTLEECLAALDGGKYGLTFASXXXXXXXXXXX-XNHGDHIVSSDDVYGGTN 448
Y R NPT E + AL GG+ + AS G +IV+ ++G T
Sbjct: 56 YTRISNPTVAEFERRVQALAGGRGVVAQASGMAAITTTILALAGAGSNIVAGRSLFGNTV 115
Query: 449 RLLRQVIARLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARS 628
LL + + G+ T F + + V A+ NT I++E+ TNP L+V D+ A+ + A++
Sbjct: 116 SLLARTLKPWGLETRFVEMKDQAAVAAAIDHNTAAIFLESITNPRLEVCDLPALAEFAQA 175
Query: 629 RGDIIVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAI 772
RG + ++VDNT T YL R GA + + S TKY++G + G I
Sbjct: 176 RG-VPLLVDNTATTFYLCRVGELGAAVEIISSTKYISGGGAAVGGLII 222
>UniRef50_Q62BJ4 Cluster: Trans-sulfuration enzyme family protein;
n=15; Burkholderia|Rep: Trans-sulfuration enzyme family
protein - Burkholderia mallei (Pseudomonas mallei)
Length = 433
Score = 86.2 bits (204), Expect = 8e-16
Identities = 57/189 (30%), Positives = 86/189 (45%), Gaps = 13/189 (6%)
Frame = +2
Query: 236 KQPAP-AEHTGFEYGRSGNPTRNTLEECLAALDGGKYGL-TFASXXXXXXXXXXXXNHGD 409
++P P E G Y R +P +E+ LA LDG + + T + GD
Sbjct: 64 RKPLPQGEAAGLVYSRFNHPNLEIVEDRLALLDGSEAAVVTSSGMSAISAIFLAFLRPGD 123
Query: 410 HIVSSDDVYGGTNRLLRQVIARLGINTTFTD------FTNIEKVKNAMQENTKMIWIETP 571
+V S +YGGT L+ + G+ D A Q ++ ++ETP
Sbjct: 124 QLVQSVPLYGGTETLIAKYFREWGVGAHSIDNGLSPQAIGAALEAAAQQGPVRLCYVETP 183
Query: 572 TNPLLKVVDIEAIVKI-----ARSRGDIIVVVDNTFLTPYLQRPLXFGADIVMYSLTKYM 736
NP ++D++ + + AR I V DNT L P Q+P G D+ +YSLTKY+
Sbjct: 184 ANPTNALIDLDGMRRELDAFEARHGYRPISVCDNTLLGPIFQKPSEHGVDMSVYSLTKYV 243
Query: 737 NGHSDVIMG 763
GHSD++ G
Sbjct: 244 GGHSDLVGG 252
>UniRef50_Q0B5H9 Cluster: Cys/Met metabolism
pyridoxal-phosphate-dependent enzymes; n=1; Burkholderia
ambifaria AMMD|Rep: Cys/Met metabolism
pyridoxal-phosphate-dependent enzymes - Burkholderia
cepacia (strain ATCC 53795 / AMMD)
Length = 384
Score = 85.8 bits (203), Expect = 1e-15
Identities = 50/182 (27%), Positives = 89/182 (48%), Gaps = 1/182 (0%)
Frame = +2
Query: 230 TFKQPAPAEHTGFEYGRSGNPTRNTLEECLAALDGGKYGLTFASXXXXXXXXXXX-XNHG 406
+F + AP + YGR G PT + L +A ++ G L S G
Sbjct: 44 SFDEMAPGA-APYHYGRWGTPTTDALCGAMAEIEHGVAALVMCSGLAAIATVLQTLAAPG 102
Query: 407 DHIVSSDDVYGGTNRLLRQVIARLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLL 586
H++ S Y + V+ R G++ + ++ + E T +++++ P +
Sbjct: 103 GHVLISRSSYPAARKFCDGVLHRQGVSIDEFSLDDPAELAAKLGERTCVVYLDLPGSSHF 162
Query: 587 KVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGA 766
+ + +V+IA G + VVVDNT+ TPY PL GA + ++S++KY+ GH+D ++GA
Sbjct: 163 DMCVLREVVEIA---GPVPVVVDNTWATPYFFNPLDHGASVAIHSMSKYIGGHADSMVGA 219
Query: 767 AI 772
A+
Sbjct: 220 AV 221
>UniRef50_A7CL93 Cluster: Cys/Met metabolism
pyridoxal-phosphate-dependent enzyme; n=1; Ralstonia
pickettii 12D|Rep: Cys/Met metabolism
pyridoxal-phosphate-dependent enzyme - Ralstonia
pickettii 12D
Length = 385
Score = 84.6 bits (200), Expect = 3e-15
Identities = 50/177 (28%), Positives = 90/177 (50%), Gaps = 1/177 (0%)
Frame = +2
Query: 263 GFEYGRSGNPTRNTLEECLAALDGGKYGLTFASXXXXXXX-XXXXXNHGDHIVSSDDVYG 439
G+ YG G PT LE +A+++GG + S + GDH++ +D VYG
Sbjct: 47 GYSYGLYGTPTTRALETEVASIEGGSRTVLVPSGLAALTHPMLALLSAGDHVLVADCVYG 106
Query: 440 GTNRLLRQVIARLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKI 619
T V+ ++G+ T+ + + +Q NT+++ +E+P + +++ +I AI +
Sbjct: 107 PTREFCNSVLRKIGVAVTYFA-ADAATIDAHLQSNTRLVLLESPGSFTMEIQEIAAISRE 165
Query: 620 ARSRGDIIVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVNDKAI 790
A + G +V++DN + G DIV +L+KY GHSDV +G+ V + +
Sbjct: 166 AHTAG-ALVMLDNAWGFGN-SAMFEHGVDIVCTALSKYAAGHSDVCLGSITVRSERL 220
>UniRef50_A1CUZ3 Cluster: Homocysteine synthase, putative; n=1;
Neosartorya fischeri NRRL 181|Rep: Homocysteine
synthase, putative - Neosartorya fischeri (strain ATCC
1020 / DSM 3700 / NRRL 181)(Aspergillus fischerianus
(strain ATCC 1020 / DSM 3700 / NRRL 181))
Length = 429
Score = 84.2 bits (199), Expect = 3e-15
Identities = 48/151 (31%), Positives = 73/151 (48%), Gaps = 1/151 (0%)
Frame = +2
Query: 314 CLAALDGGKYGLTFASXXXXXXXXXXXXNHGDHIVSSDDVYGGTNRLLRQVIARLGINTT 493
C+ + G T + GD+IV+S V+GGT + + +LGI
Sbjct: 86 CMPTVRGVAACATASGTAAVSMTLMALAGVGDNIVASSTVHGGTYHQFKVLAPQLGIECR 145
Query: 494 FTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTF-LT 670
F E + ++ TK I++E+ +NP V D EA+ I S G + ++ DNTF
Sbjct: 146 FVASNEPEDFRALLEGKTKFIFVESISNPKYTVPDFEALADITHSHG-VPLICDNTFGCA 204
Query: 671 PYLQRPLXFGADIVMYSLTKYMNGHSDVIMG 763
Y RP+ GADIV+YS K++ GH + G
Sbjct: 205 GYYCRPIEHGADIVVYSARKWIGGHGTTLGG 235
>UniRef50_A1W861 Cluster: Cys/Met metabolism
pyridoxal-phosphate-dependent enzymes; n=10; cellular
organisms|Rep: Cys/Met metabolism
pyridoxal-phosphate-dependent enzymes - Acidovorax sp.
(strain JS42)
Length = 415
Score = 83.8 bits (198), Expect = 5e-15
Identities = 61/225 (27%), Positives = 104/225 (46%), Gaps = 12/225 (5%)
Frame = +2
Query: 164 HAGQEPEKWNSAAVVTPIVTSTTFKQPAPAEHTGFEYGRSGNPTRNTLEECLAALDGGKY 343
HA Q P ++ V+ P V + ++ + + + YG G PT LEE LA L+GG
Sbjct: 25 HAPQ-PAVHKASTVIFPNVAAMRAREWK--DKSSYTYGLHGTPTTYQLEERLATLEGGLQ 81
Query: 344 GLTFASXXXXXXXXXXXX-NHGDHIVSSDDVYGGTNRLLRQVIARLGINTTFTDFTNIEK 520
L S GD ++ D+ YG L + GI D +
Sbjct: 82 CLLVPSGLAAISTVSLALLRQGDEVLIPDNAYGPNKALAEVELRHYGIRHRIYDPLDPAD 141
Query: 521 VKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTF-----LTPY--L 679
+ + + + T+++W+E P + L+ D+ V+I R+RG + V+DNT+ P+ L
Sbjct: 142 LASKITDATRLVWLEAPGSVTLEFPDLVEQVRICRARG-VATVLDNTWGAGLAFAPFDLL 200
Query: 680 QRPL----XFGADIVMYSLTKYMNGHSDVIMGAAIVNDKAIGXKL 802
R G D+ +++LTKY +G DV+MG+ D+ + ++
Sbjct: 201 GRGARAEGALGVDVSVHALTKYPSGGGDVLMGSITTRDEGLHLRI 245
>UniRef50_Q5NQQ3 Cluster: Cystathionine beta-lyase; n=41;
Proteobacteria|Rep: Cystathionine beta-lyase - Zymomonas
mobilis
Length = 682
Score = 82.6 bits (195), Expect = 1e-14
Identities = 54/198 (27%), Positives = 88/198 (44%), Gaps = 2/198 (1%)
Frame = +2
Query: 179 PEKWNSAAVVTPIVTSTTFKQPAPAEHTGFEYGRSGNPTRNTLEECLAALD-GGKYGLTF 355
P W ++ ++ V P + YGR G PT+ L E L L G + + +
Sbjct: 311 PPVWRASTILFDSVEDLREASSHPDDQ--LYYGRRGTPTQWALSEALTELHPGAEATMLY 368
Query: 356 ASXXXXXXXXXXXX-NHGDHIVSSDDVYGGTNRLLRQVIARLGINTTFTDFTNIEKVKNA 532
S GD ++ D Y T V+ GIN T+ D + ++
Sbjct: 369 PSGVAALSMALLSALEAGDELLMVDSCYEPTRVFCDTVLKAQGINVTYYDPLIGQDIEQL 428
Query: 533 MQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQRPLXFGADIV 712
T+ I++E+P + +V DI I ++A R I ++DNT+ TP + G D+
Sbjct: 429 FTPQTRAIFMESPGSLTFEVQDIPGICEVAH-RYSITTILDNTWATPLFFPAIERGVDLS 487
Query: 713 MYSLTKYMNGHSDVIMGA 766
+ + TKY+ GHSD +MG+
Sbjct: 488 VMACTKYITGHSDTMMGS 505
>UniRef50_Q7P3Q8 Cluster: Methionine gamma-lyase; n=1; Fusobacterium
nucleatum subsp. vincentii ATCC 49256|Rep: Methionine
gamma-lyase - Fusobacterium nucleatum subsp. vincentii
ATCC 49256
Length = 79
Score = 82.2 bits (194), Expect = 1e-14
Identities = 31/71 (43%), Positives = 55/71 (77%)
Frame = +2
Query: 452 LLRQVIARLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSR 631
++ + +LG+ TF D +N+++VK AM++NT+++++ETP NP LK+VD+EA+ K+A +
Sbjct: 1 MMNHGLTKLGVEVTFVDTSNLDEVKKAMKKNTRVVYLETPANPNLKIVDLEALAKLAHTN 60
Query: 632 GDIIVVVDNTF 664
+ +V+VDNTF
Sbjct: 61 PNTLVIVDNTF 71
>UniRef50_Q6F7Q9 Cluster: Putative cystathionine beta-lyase,
PLP-dependent; n=1; Acinetobacter sp. ADP1|Rep: Putative
cystathionine beta-lyase, PLP-dependent - Acinetobacter
sp. (strain ADP1)
Length = 397
Score = 79.8 bits (188), Expect = 7e-14
Identities = 57/220 (25%), Positives = 104/220 (47%), Gaps = 6/220 (2%)
Frame = +2
Query: 161 IHAGQEPEKWNSAAVVTPIVTSTTFKQPAPAEHTGFEYGRSGNPTRNTLEECLAALDGGK 340
IH+ Q P + ++ ++ P T+ F + ++ + YG G PT TL + LA ++GG+
Sbjct: 22 IHSIQPP-LFRASTIIFP-TTAHLFDRHW-SDPYDYSYGTHGTPTTFTLGDQLAEIEGGQ 78
Query: 341 YGLTFASXXXXXXXXXXXX-NHGDHIVSSDDVYGGTNRLLRQVIARLGINTTFTDFTNIE 517
Y L S +HGD + D++YG L + R GI + I+
Sbjct: 79 YCLLAPSGLSAINLVNSTFLSHGDEVWVPDNIYGPNMEHLNNLRQRYGIQVRI--YNPID 136
Query: 518 KVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTFLTPYLQRPLXF 697
E T+++W+E + ++ D+ +V+ A++ ++ +DNT+ F
Sbjct: 137 AESFIPSEKTRLLWLEAAGSITMEFPDLIQLVRKAQA-AQVLTALDNTWGAGLAFNAFDF 195
Query: 698 G-----ADIVMYSLTKYMNGHSDVIMGAAIVNDKAIGXKL 802
DI +++LTKY +G D++MG+ I DK + +L
Sbjct: 196 SNEHLSVDITVHALTKYPSGGGDILMGSVITRDKNLYQQL 235
>UniRef50_Q9YA71 Cluster: Cystathionine gamma-synthase; n=1;
Aeropyrum pernix|Rep: Cystathionine gamma-synthase -
Aeropyrum pernix
Length = 389
Score = 79.8 bits (188), Expect = 7e-14
Identities = 67/217 (30%), Positives = 98/217 (45%), Gaps = 9/217 (4%)
Frame = +2
Query: 143 GFATIAIHAGQEPEKWN-SAAVVTPIVTSTTFKQPAPAEHTGF------EYGRSGNPTRN 301
G+ T + G P K VV P+ S + P + + +YGR NPT
Sbjct: 2 GWVTRWVRGGWRPSKDPVREPVVPPVNVSAIYVHPPGSFEREYPRVGDLKYGRENNPTVL 61
Query: 302 TLEECLAALDGGKYGLTFASXXXXXXXXXXXX-NHGDHIVSSDDV-YGGTNRLLRQVIAR 475
LEE L +L+ ++ L F S + G V + + YG T LL + +
Sbjct: 62 GLEEALTSLEEARWTLAFNSGMAALSTLVLHEVSRGAKKVLLERLTYGSTRSLLEMLSSI 121
Query: 476 LGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVD 655
GI + + + +I +E+ NP L+V + I + A S G + VVVD
Sbjct: 122 TGIEVRLAGPPWEDLLDLVCWAD--LIIVESMANPTLRVPPLSGIYREAGSCG-VRVVVD 178
Query: 656 NTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGA 766
NTF TP RPL GA + SLTKY+ GH+DV+ G+
Sbjct: 179 NTFATPIAYRPLERGAHYSLESLTKYIAGHNDVVGGS 215
>UniRef50_O42851 Cluster: Uncharacterized trans-sulfuration enzyme
C23A1.14c; n=1; Schizosaccharomyces pombe|Rep:
Uncharacterized trans-sulfuration enzyme C23A1.14c -
Schizosaccharomyces pombe (Fission yeast)
Length = 398
Score = 79.8 bits (188), Expect = 7e-14
Identities = 45/118 (38%), Positives = 70/118 (59%)
Frame = +2
Query: 434 YGGTNRLLRQVIARLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIV 613
Y GT +++ ++ G+ T+F I+ +A+ E +IW+ETP NPL DI
Sbjct: 121 YSGTIQIIARINRLTGLETSF-----IDGKCDAIGEGD-VIWLETPLNPLGIAFDIPFYK 174
Query: 614 KIARSRGDIIVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVNDKA 787
++A+ +G I+VV D+TF P +Q L GAD V++S TKY+ GHSDV+ G D++
Sbjct: 175 ELAKKKGAILVV-DSTFAPPPIQDALVLGADYVVHSATKYLAGHSDVLAGVTASKDRS 231
>UniRef50_A7TA32 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 175
Score = 79.4 bits (187), Expect = 1e-13
Identities = 57/176 (32%), Positives = 87/176 (49%), Gaps = 24/176 (13%)
Frame = +2
Query: 131 KQKPGFATIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPAPAE--------HTGFEYGRSG 286
+QK GF TI IH G + E N+ A +TPI S+T+ + + G+ YGR G
Sbjct: 4 QQKKGFETICIHGGHQQE--NNRAHLTPIYASSTYTFDSAEQAVNIFQGKEEGYVYGRFG 61
Query: 287 NPTRNTLEECLAALDGGKYGLTFA------------SXXXXXXXXXXXXN--HGDHIVSS 424
NPT EE +A ++ YGL + S N G+ I++
Sbjct: 62 NPTIREAEEKIALMEA--YGLQDSNGDNLELKAILHSSGMAAITTMLLSNLKAGEKIITH 119
Query: 425 DDVYGGTNRLLRQVIARLGINTTFTDFTNIEKVKNAMQENT--KMIWIETPTNPLL 586
+YGGT L+ +V+ +GI DF N++KV+ A+Q ++ +++IETP NP L
Sbjct: 120 YSLYGGTQELIDKVLPDMGIEVIIADFNNLDKVEAAIQADSAINLMYIETPANPTL 175
>UniRef50_P38716 Cluster: Uncharacterized trans-sulfuration enzyme
YHR112C; n=5; Saccharomycetales|Rep: Uncharacterized
trans-sulfuration enzyme YHR112C - Saccharomyces
cerevisiae (Baker's yeast)
Length = 378
Score = 78.6 bits (185), Expect = 2e-13
Identities = 50/177 (28%), Positives = 83/177 (46%)
Frame = +2
Query: 272 YGRSGNPTRNTLEECLAALDGGKYGLTFASXXXXXXXXXXXXNHGDHIVSSDDVYGGTNR 451
Y R +P LE + + G Y + ++S N + Y G
Sbjct: 56 YSRLAHPNSTRLESIFSEILDG-YAVIYSSGLAAFYAAMVHYNPKKIFIGQS--YHGVRA 112
Query: 452 LLRQVIARLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSR 631
+ + GI +E ++ E ++ +E+P NP DIE++ + A ++
Sbjct: 113 IANILTRNYGIEQH-----PLEDIEKCASEGD-IVHLESPVNPYGTSSDIESLARRAHAK 166
Query: 632 GDIIVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVNDKAIGXKL 802
G +++V D+TF +P LQ FGADIV+YS TKY GHSD++ G +V ++A +L
Sbjct: 167 GALLIV-DSTFASPPLQYAWNFGADIVLYSATKYFGGHSDLLSGVLVVKEEATSRQL 222
>UniRef50_A5W0L6 Cluster: Cys/Met metabolism
pyridoxal-phosphate-dependent enzyme; n=3; Pseudomonas
putida|Rep: Cys/Met metabolism
pyridoxal-phosphate-dependent enzyme - Pseudomonas
putida F1
Length = 397
Score = 78.2 bits (184), Expect = 2e-13
Identities = 50/176 (28%), Positives = 80/176 (45%), Gaps = 1/176 (0%)
Frame = +2
Query: 260 TGFEYGRSGNPTRNTLEECLAALDGGKYG-LTFASXXXXXXXXXXXXNHGDHIVSSDDVY 436
+G YG PT L + +A L+ GK+ LT + GDH+++ D +
Sbjct: 64 SGLYYGGVDTPTTRQLSQRVADLEKGKFAVLTPSGQSAFNLLLTTFVKPGDHVLAGDTIV 123
Query: 437 GGTNRLLRQVIARLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVK 616
T LL +G+ + + +KN + TK+I E P +V++I AIV+
Sbjct: 124 YSTRWLLNH-FENIGVKIEYFTPSEAATLKNKLTLKTKLIIFENPGAFTYEVMNINAIVE 182
Query: 617 IARSRGDIIVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAIVNDK 784
+R ++V DNT+ PL GADI + S++KY + +GA I K
Sbjct: 183 -SRHDHPALIVADNTWAASLFHHPLSLGADISLISMSKYHGAVEGISLGALITKRK 237
>UniRef50_Q64XN5 Cluster: O-acetylhomoserine sulfhydrylase; n=3;
Bacteroides|Rep: O-acetylhomoserine sulfhydrylase -
Bacteroides fragilis
Length = 411
Score = 77.8 bits (183), Expect = 3e-13
Identities = 48/174 (27%), Positives = 81/174 (46%), Gaps = 1/174 (0%)
Frame = +2
Query: 254 EHTGFEYGRSGNPTRNTLEECLAALDGGKYGLTFASXXXXXXXXXXX-XNHGDHIVSSDD 430
+ G Y R NPT E+ + + G S + G ++V+S
Sbjct: 49 QKAGHAYSRITNPTVQYFEQRVQRVTGALSVTALNSGMAAISNALITLASAGANVVTSKH 108
Query: 431 VYGGTNRLLRQVIARLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAI 610
++G T L+ + G+ F D T E+VK + +T +++E TNP L+V D++A+
Sbjct: 109 LFGNTYSFLKSTLEAFGVEVRFCDLTCPEEVKQQIDGDTCALFLEVITNPQLEVADLKAL 168
Query: 611 VKIARSRGDIIVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAI 772
IA G + ++ D T + ++ FG DI + S TKY++G + I G I
Sbjct: 169 ADIAHKAG-VPLLADTTAIPFHVFHATDFGVDIEIVSSTKYISGGATCIGGLII 221
>UniRef50_A3UCF8 Cluster: Cystathionine beta-lyase; n=1;
Oceanicaulis alexandrii HTCC2633|Rep: Cystathionine
beta-lyase - Oceanicaulis alexandrii HTCC2633
Length = 381
Score = 77.8 bits (183), Expect = 3e-13
Identities = 63/214 (29%), Positives = 90/214 (42%), Gaps = 9/214 (4%)
Frame = +2
Query: 152 TIAIHAGQEPEKWNSAAVVTPIVTSTTFKQPAPAEHTG-----FEYGRSGNPTRNTLEEC 316
T IH+GQ P + N V PI ++T P AE YGR G L E
Sbjct: 5 TRLIHSGQ-PRR-NDDLVNPPIERASTVVAPTTAELYNPTPPRRHYGRGGLSPNMELREA 62
Query: 317 LAALDGGKY-GLT---FASXXXXXXXXXXXXNHGDHIVSSDDVYGGTNRLLRQVIARLGI 484
+ L G + L AS G + +D YG R + + R G+
Sbjct: 63 IGELYGADHVSLAQSGLASVILALRTALPENPAGMQALITDSAYGPVRRFCDEELPRYGV 122
Query: 485 NTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARSRGDIIVVVDNTF 664
+ D V + + T ++ +E+P + +V DI AI AR G + V+D+T+
Sbjct: 123 TPVYYDPRIGAGVAELLDKPTAVVLLESPGSLTFEVQDIPAIAGAARKAG-VATVIDDTW 181
Query: 665 LTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGA 766
L PL G D +LTKY GHSD +MG+
Sbjct: 182 SAGVLMNPLELGVDYAAQALTKYAGGHSDFLMGS 215
>UniRef50_Q28LE3 Cluster: Cys/Met metabolism
pyridoxal-phosphate-dependent enzyme; n=2;
Rhodobacteraceae|Rep: Cys/Met metabolism
pyridoxal-phosphate-dependent enzyme - Jannaschia sp.
(strain CCS1)
Length = 383
Score = 77.0 bits (181), Expect = 5e-13
Identities = 42/168 (25%), Positives = 79/168 (47%), Gaps = 1/168 (0%)
Frame = +2
Query: 272 YGRSGNPTRNTLEECLAALDGGKYGLTFASXXXXXXXXXXXX-NHGDHIVSSDDVYGGTN 448
Y R NPT E +A + G+ + FAS GD I + Y T
Sbjct: 53 YTRVQNPTVAAFEGLMAQAEEGEAAVGFASGMAAISSTLLAFVKPGDRIACIEHAYPDTY 112
Query: 449 RLLRQVIARLGINTTFTDFTNIEKVKNAMQENTKMIWIETPTNPLLKVVDIEAIVKIARS 628
R +++ G+ + E + + + ++E+P++ + +++ + + A
Sbjct: 113 RFFERMLRPFGVQIDYHPARAFEDDPDLLN-GVAIAYLESPSSVVFTPMNLARVAEHATR 171
Query: 629 RGDIIVVVDNTFLTPYLQRPLXFGADIVMYSLTKYMNGHSDVIMGAAI 772
G + ++DN++ +P QRPL G DIV++S +KY++GHSD + G +
Sbjct: 172 HGTV-TMIDNSWASPVFQRPLTLGIDIVLHSASKYISGHSDTVAGVVV 218
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 775,812,100
Number of Sequences: 1657284
Number of extensions: 16072318
Number of successful extensions: 46821
Number of sequences better than 10.0: 351
Number of HSP's better than 10.0 without gapping: 44315
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 46264
length of database: 575,637,011
effective HSP length: 99
effective length of database: 411,565,895
effective search space used: 68731504465
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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