Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P17_F_H12
(703 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q24320 Cluster: DNA-directed RNA polymerases I, II, and... 176 5e-43
UniRef50_P61218 Cluster: DNA-directed RNA polymerases I, II, and... 151 2e-35
UniRef50_Q17684 Cluster: Probable DNA-directed RNA polymerases I... 132 8e-30
UniRef50_A5E2K4 Cluster: DNA-directed RNA polymerases I; n=7; Sa... 129 6e-29
UniRef50_Q01F81 Cluster: RNA polymerase subunit K; n=4; Eukaryot... 128 2e-28
UniRef50_P20435 Cluster: DNA-directed RNA polymerases I, II, and... 127 2e-28
UniRef50_Q758N4 Cluster: AEL279Cp; n=3; Fungi/Metazoa group|Rep:... 126 4e-28
UniRef50_Q1DXT5 Cluster: Putative uncharacterized protein; n=1; ... 124 2e-27
UniRef50_Q9FJ98 Cluster: DNA-directed RNA polymerase II subunit-... 124 3e-27
UniRef50_Q54FA8 Cluster: RNA polymerase II core subunit; n=3; Eu... 123 4e-27
UniRef50_Q4Q3B6 Cluster: DNA-directed RNA polymerase subunit, pu... 114 2e-24
UniRef50_UPI000049A526 Cluster: DNA-directed RNA polymerases sub... 111 2e-23
UniRef50_UPI0000E25B17 Cluster: PREDICTED: similar to RNA polyme... 102 7e-21
UniRef50_A0CFC7 Cluster: Chromosome undetermined scaffold_175, w... 98 2e-19
UniRef50_Q8SRE9 Cluster: DNA-DIRECTED RNA POLYMERASE I; n=1; Enc... 98 2e-19
UniRef50_Q7QX02 Cluster: GLP_511_21202_20888; n=2; Giardia intes... 97 3e-19
UniRef50_UPI00006CFA18 Cluster: RNA polymerases K / 14 to 18 kDa... 97 5e-19
UniRef50_A2E3F1 Cluster: DNA-directed RNA polymerases I, II, and... 97 5e-19
UniRef50_O77315 Cluster: DNA-directed RNA polymerase subunit I, ... 87 5e-16
UniRef50_Q3LW93 Cluster: DNA-directed RNA polymerase I, II and I... 82 1e-14
UniRef50_Q6W391 Cluster: Predicted DNA-directed RNA polymerase I... 69 1e-10
UniRef50_Q8PW42 Cluster: DNA-directed RNA polymerase subunit K; ... 68 3e-10
UniRef50_Q8TV21 Cluster: DNA-directed RNA polymerase subunit K/o... 67 3e-10
UniRef50_Q84Q45 Cluster: Putative DNA-directed RNA polymerase Ii... 65 1e-09
UniRef50_A1RWX0 Cluster: RNA polymerase Rpb6; n=1; Thermofilum p... 64 3e-09
UniRef50_Q9YDJ9 Cluster: DNA-directed RNA polymerase subunit K; ... 64 4e-09
UniRef50_Q0W8C8 Cluster: DNA-directed RNA polymerase, subunit K;... 63 7e-09
UniRef50_O29134 Cluster: DNA-directed RNA polymerase subunit K; ... 62 1e-08
UniRef50_Q8ZTF9 Cluster: DNA-directed RNA polymerase subunit K; ... 60 5e-08
UniRef50_A0RUC3 Cluster: DNA-directed RNA polymerase, subunit K/... 59 9e-08
UniRef50_Q6L1M4 Cluster: DNA-directed RNA polymerase subunit K; ... 58 3e-07
UniRef50_Q5UQ32 Cluster: DNA-directed RNA polymerase subunit 6; ... 57 4e-07
UniRef50_Q97ZJ9 Cluster: DNA-directed RNA polymerase subunit K; ... 56 1e-06
UniRef50_O26148 Cluster: DNA-directed RNA polymerase subunit K; ... 55 2e-06
UniRef50_A7DMM8 Cluster: RNA polymerase Rpb6; n=1; Candidatus Ni... 54 3e-06
UniRef50_Q9HQJ0 Cluster: DNA-directed RNA polymerase subunit K; ... 51 3e-05
UniRef50_A3H7H2 Cluster: RNA polymerase Rpb6; n=1; Caldivirga ma... 50 4e-05
UniRef50_UPI00015BAACE Cluster: DNA-directed RNA polymerase, sub... 48 3e-04
UniRef50_A4YHC6 Cluster: RNA polymerase Rpb6; n=1; Metallosphaer... 46 9e-04
UniRef50_Q387N1 Cluster: DNA-directed RNA polymerase subunit, pu... 44 0.004
UniRef50_Q57650 Cluster: DNA-directed RNA polymerase subunit K; ... 43 0.006
UniRef50_A3BJH4 Cluster: Putative uncharacterized protein; n=3; ... 39 0.14
UniRef50_Q4A221 Cluster: Putative uncharacterized protein; n=1; ... 35 1.7
UniRef50_Q38000 Cluster: Orf15 protein; n=1; Streptococcus phage... 34 2.9
>UniRef50_Q24320 Cluster: DNA-directed RNA polymerases I, II, and
III subunit RPABC2; n=5; Bilateria|Rep: DNA-directed RNA
polymerases I, II, and III subunit RPABC2 - Drosophila
melanogaster (Fruit fly)
Length = 131
Score = 176 bits (428), Expect = 5e-43
Identities = 83/110 (75%), Positives = 97/110 (88%), Gaps = 1/110 (0%)
Frame = +3
Query: 189 DNIEXTEXQEEDGYNVQCLALGQAGGG-VDKSKRITTRYMTKYERARVLGTRALQIAMCS 365
++++ QEE+ N++ +A G AGGG V KSKRITT+YMTKYERARVLGTRALQIAMC+
Sbjct: 21 EDVDEDINQEEEADNIEIIAPGGAGGGGVPKSKRITTKYMTKYERARVLGTRALQIAMCA 80
Query: 366 PVMVELEGETDPLQIAMKELKHGKIPIIIRRYLPDHSYEDWSIDELIIID 515
P+MVEL+GETDPLQIAMKELK KIPIIIRRYLPDHSYEDWSIDELI++D
Sbjct: 81 PIMVELDGETDPLQIAMKELKQKKIPIIIRRYLPDHSYEDWSIDELIMVD 130
>UniRef50_P61218 Cluster: DNA-directed RNA polymerases I, II, and
III subunit RPABC2; n=34; cellular organisms|Rep:
DNA-directed RNA polymerases I, II, and III subunit
RPABC2 - Homo sapiens (Human)
Length = 127
Score = 151 bits (365), Expect = 2e-35
Identities = 78/113 (69%), Positives = 86/113 (76%), Gaps = 1/113 (0%)
Frame = +3
Query: 180 EXXDNIEXTEXQEEDGY-NVQCLALGQAGGGVDKSKRITTRYMTKYERARVLGTRALQIA 356
E + ++ E EE+G NV+ L G+ KRITT YMTKYERARVLGTRALQIA
Sbjct: 17 EEDEGLDDLENAEEEGQENVEILPSGERPQA--NQKRITTPYMTKYERARVLGTRALQIA 74
Query: 357 MCSPVMVELEGETDPLQIAMKELKHGKIPIIIRRYLPDHSYEDWSIDELIIID 515
MC+PVMVELEGETDPL IAMKELK KIPIIIRRYLPD SYEDW +DELII D
Sbjct: 75 MCAPVMVELEGETDPLLIAMKELKARKIPIIIRRYLPDGSYEDWGVDELIITD 127
>UniRef50_Q17684 Cluster: Probable DNA-directed RNA polymerases I,
II, and III subunit RPABC2; n=4; Bilateria|Rep: Probable
DNA-directed RNA polymerases I, II, and III subunit
RPABC2 - Caenorhabditis elegans
Length = 137
Score = 132 bits (319), Expect = 8e-30
Identities = 66/104 (63%), Positives = 79/104 (75%), Gaps = 1/104 (0%)
Frame = +3
Query: 207 EXQEEDGYNV-QCLALGQAGGGVDKSKRITTRYMTKYERARVLGTRALQIAMCSPVMVEL 383
+ ++ED NV + L G V S+ +TT +MTKYERARVLGTRALQIAM +PVMVEL
Sbjct: 33 DNEDEDDDNVDENFELFDQGKAVPTSEHVTTPFMTKYERARVLGTRALQIAMGAPVMVEL 92
Query: 384 EGETDPLQIAMKELKHGKIPIIIRRYLPDHSYEDWSIDELIIID 515
EGETDPL+IA KELK +IPII+RRYLPD SYEDW D+L + D
Sbjct: 93 EGETDPLEIARKELKQRRIPIIVRRYLPDGSYEDWPTDQLQLAD 136
>UniRef50_A5E2K4 Cluster: DNA-directed RNA polymerases I; n=7;
Saccharomycetales|Rep: DNA-directed RNA polymerases I -
Lodderomyces elongisporus (Yeast) (Saccharomyces
elongisporus)
Length = 165
Score = 129 bits (312), Expect = 6e-29
Identities = 58/80 (72%), Positives = 69/80 (86%)
Frame = +3
Query: 270 VDKSKRITTRYMTKYERARVLGTRALQIAMCSPVMVELEGETDPLQIAMKELKHGKIPII 449
+ K KR TT YMTKYERAR+LGTRALQI++ +PV+V++EGETDPLQIAMKEL KIP++
Sbjct: 84 IPKEKRTTTPYMTKYERARILGTRALQISLNAPVLVDIEGETDPLQIAMKELAQRKIPLV 143
Query: 450 IRRYLPDHSYEDWSIDELII 509
IRRYLPD SYEDW DELI+
Sbjct: 144 IRRYLPDGSYEDWGCDELIV 163
>UniRef50_Q01F81 Cluster: RNA polymerase subunit K; n=4;
Eukaryota|Rep: RNA polymerase subunit K - Ostreococcus
tauri
Length = 149
Score = 128 bits (308), Expect = 2e-28
Identities = 58/85 (68%), Positives = 71/85 (83%)
Frame = +3
Query: 261 GGGVDKSKRITTRYMTKYERARVLGTRALQIAMCSPVMVELEGETDPLQIAMKELKHGKI 440
GG V + R TT YMTKYERARVLGTRALQI+M +PV+V+LEGETDPL+IA KEL+ ++
Sbjct: 59 GGAVPRHLRTTTPYMTKYERARVLGTRALQISMNAPVLVQLEGETDPLEIAGKELREKRV 118
Query: 441 PIIIRRYLPDHSYEDWSIDELIIID 515
P ++RRYLPD SYEDW I+ELI+ D
Sbjct: 119 PFVVRRYLPDGSYEDWCIEELIVHD 143
>UniRef50_P20435 Cluster: DNA-directed RNA polymerases I, II, and
III subunit RPABC2; n=16; Ascomycota|Rep: DNA-directed
RNA polymerases I, II, and III subunit RPABC2 -
Saccharomyces cerevisiae (Baker's yeast)
Length = 155
Score = 127 bits (307), Expect = 2e-28
Identities = 57/80 (71%), Positives = 70/80 (87%)
Frame = +3
Query: 270 VDKSKRITTRYMTKYERARVLGTRALQIAMCSPVMVELEGETDPLQIAMKELKHGKIPII 449
+ K +R TT YMTKYERAR+LGTRALQI+M +PV V+LEGETDPL+IAMKEL KIP++
Sbjct: 74 IPKDQRATTPYMTKYERARILGTRALQISMNAPVFVDLEGETDPLRIAMKELAEKKIPLV 133
Query: 450 IRRYLPDHSYEDWSIDELII 509
IRRYLPD S+EDWS++ELI+
Sbjct: 134 IRRYLPDGSFEDWSVEELIV 153
>UniRef50_Q758N4 Cluster: AEL279Cp; n=3; Fungi/Metazoa group|Rep:
AEL279Cp - Ashbya gossypii (Yeast) (Eremothecium
gossypii)
Length = 154
Score = 126 bits (305), Expect = 4e-28
Identities = 56/80 (70%), Positives = 70/80 (87%)
Frame = +3
Query: 270 VDKSKRITTRYMTKYERARVLGTRALQIAMCSPVMVELEGETDPLQIAMKELKHGKIPII 449
+ K +R TT YMTKYERAR+LGTRALQI+M +PV V+LEGETDP++IAMKEL KIP++
Sbjct: 73 IPKEERTTTPYMTKYERARILGTRALQISMNAPVFVDLEGETDPMRIAMKELAEKKIPLV 132
Query: 450 IRRYLPDHSYEDWSIDELII 509
IRRYLPD S+EDWS++ELI+
Sbjct: 133 IRRYLPDGSFEDWSVEELIV 152
>UniRef50_Q1DXT5 Cluster: Putative uncharacterized protein; n=1;
Coccidioides immitis|Rep: Putative uncharacterized
protein - Coccidioides immitis
Length = 142
Score = 124 bits (299), Expect = 2e-27
Identities = 64/114 (56%), Positives = 79/114 (69%), Gaps = 5/114 (4%)
Frame = +3
Query: 180 EXXDNIEXTEXQEEDGYNV-----QCLALGQAGGGVDKSKRITTRYMTKYERARVLGTRA 344
E D + + EE Y V Q + L Q V +R TT YMTKYERARVLGTRA
Sbjct: 29 EPEDYVSPEQEAEEGAYAVLNGDGQPVMLQQREKKVPNDQRTTTPYMTKYERARVLGTRA 88
Query: 345 LQIAMCSPVMVELEGETDPLQIAMKELKHGKIPIIIRRYLPDHSYEDWSIDELI 506
LQI+M +P++V+LEGETDPLQIA+KEL KIP+I+RRYLPD YEDW+ +EL+
Sbjct: 89 LQISMNAPILVDLEGETDPLQIALKELNQKKIPLIVRRYLPDGWYEDWTCEELL 142
>UniRef50_Q9FJ98 Cluster: DNA-directed RNA polymerase II
subunit-like protein; n=13; cellular organisms|Rep:
DNA-directed RNA polymerase II subunit-like protein -
Arabidopsis thaliana (Mouse-ear cress)
Length = 144
Score = 124 bits (298), Expect = 3e-27
Identities = 56/77 (72%), Positives = 68/77 (88%)
Frame = +3
Query: 285 RITTRYMTKYERARVLGTRALQIAMCSPVMVELEGETDPLQIAMKELKHGKIPIIIRRYL 464
R T+++MTKYERAR+LGTRALQI+M +PVMVELEGETDPL+IAMKEL+ KIP IRRYL
Sbjct: 59 RKTSKFMTKYERARILGTRALQISMNAPVMVELEGETDPLEIAMKELRQRKIPFTIRRYL 118
Query: 465 PDHSYEDWSIDELIIID 515
PD S+E+W +DELI+ D
Sbjct: 119 PDGSFEEWGVDELIVED 135
>UniRef50_Q54FA8 Cluster: RNA polymerase II core subunit; n=3;
Eukaryota|Rep: RNA polymerase II core subunit -
Dictyostelium discoideum AX4
Length = 133
Score = 123 bits (297), Expect = 4e-27
Identities = 58/82 (70%), Positives = 69/82 (84%)
Frame = +3
Query: 264 GGVDKSKRITTRYMTKYERARVLGTRALQIAMCSPVMVELEGETDPLQIAMKELKHGKIP 443
G + R TTRYMTKYERAR+LG+RALQI+M +P+MVELEGETDPLQIA KEL+ KIP
Sbjct: 52 GRIPNHLRKTTRYMTKYERARLLGSRALQISMNAPIMVELEGETDPLQIAWKELRAKKIP 111
Query: 444 IIIRRYLPDHSYEDWSIDELII 509
+IIRR+LP+ YEDWS+DEL I
Sbjct: 112 LIIRRFLPNGMYEDWSVDELSI 133
>UniRef50_Q4Q3B6 Cluster: DNA-directed RNA polymerase subunit,
putative; n=5; Trypanosomatidae|Rep: DNA-directed RNA
polymerase subunit, putative - Leishmania major
Length = 159
Score = 114 bits (274), Expect = 2e-24
Identities = 59/114 (51%), Positives = 77/114 (67%), Gaps = 3/114 (2%)
Frame = +3
Query: 177 AEXXDNIEXTEXQEEDGYNVQCLALGQAGGGVDK---SKRITTRYMTKYERARVLGTRAL 347
A+ D + E+ NV QA G ++R+T+ MTKYERARVLGTRAL
Sbjct: 33 ADEEDEEGGEQLPEDVAANVILSGNAQAAKGARARGINERVTSAVMTKYERARVLGTRAL 92
Query: 348 QIAMCSPVMVELEGETDPLQIAMKELKHGKIPIIIRRYLPDHSYEDWSIDELII 509
QI+M +PV V LEGETDPL IA+KEL+ + P+IIRR LPD++YEDWS+ EL++
Sbjct: 93 QISMNAPVAVALEGETDPLTIAVKELRERRTPLIIRRVLPDNTYEDWSVSELLV 146
>UniRef50_UPI000049A526 Cluster: DNA-directed RNA polymerases
subunit; n=1; Entamoeba histolytica HM-1:IMSS|Rep:
DNA-directed RNA polymerases subunit - Entamoeba
histolytica HM-1:IMSS
Length = 122
Score = 111 bits (267), Expect = 2e-23
Identities = 53/75 (70%), Positives = 61/75 (81%)
Frame = +3
Query: 285 RITTRYMTKYERARVLGTRALQIAMCSPVMVELEGETDPLQIAMKELKHGKIPIIIRRYL 464
R TTR+MTKYE+ARVLGTRALQI+M +PV V L G TD L+IAM ELK GKIP IIRR L
Sbjct: 47 RTTTRFMTKYEKARVLGTRALQISMNAPVFVPLNGMTDALEIAMAELKAGKIPFIIRRRL 106
Query: 465 PDHSYEDWSIDELII 509
P+ SYEDW + ELI+
Sbjct: 107 PNGSYEDWKVSELIV 121
>UniRef50_UPI0000E25B17 Cluster: PREDICTED: similar to RNA
polymerase II isoform 1; n=1; Pan troglodytes|Rep:
PREDICTED: similar to RNA polymerase II isoform 1 - Pan
troglodytes
Length = 126
Score = 102 bits (245), Expect = 7e-21
Identities = 55/84 (65%), Positives = 62/84 (73%), Gaps = 1/84 (1%)
Frame = +3
Query: 180 EXXDNIEXTEXQEEDGY-NVQCLALGQAGGGVDKSKRITTRYMTKYERARVLGTRALQIA 356
E + ++ E EE+G NV+ L G+ KRITT YMTKYERARVLGTRALQIA
Sbjct: 17 EEDEGLDDLENAEEEGQENVEILPSGERPQA--NQKRITTPYMTKYERARVLGTRALQIA 74
Query: 357 MCSPVMVELEGETDPLQIAMKELK 428
MC+PVMVELEGETDPL IAMKELK
Sbjct: 75 MCAPVMVELEGETDPLLIAMKELK 98
>UniRef50_A0CFC7 Cluster: Chromosome undetermined scaffold_175,
whole genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_175,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 156
Score = 98.3 bits (234), Expect = 2e-19
Identities = 45/85 (52%), Positives = 62/85 (72%)
Frame = +3
Query: 261 GGGVDKSKRITTRYMTKYERARVLGTRALQIAMCSPVMVELEGETDPLQIAMKELKHGKI 440
G V+K +RIT ++TKYERARV+GTRALQI+ SP+ V+ + TDP+ +A +EL KI
Sbjct: 72 GKKVNKDERITPPFLTKYERARVIGTRALQISKNSPIYVDPKETTDPILVAQQELNENKI 131
Query: 441 PIIIRRYLPDHSYEDWSIDELIIID 515
P IIRRY P+ ++EDW + EL +D
Sbjct: 132 PFIIRRYWPNGNFEDWELQELERLD 156
>UniRef50_Q8SRE9 Cluster: DNA-DIRECTED RNA POLYMERASE I; n=1;
Encephalitozoon cuniculi|Rep: DNA-DIRECTED RNA
POLYMERASE I - Encephalitozoon cuniculi
Length = 144
Score = 98.3 bits (234), Expect = 2e-19
Identities = 46/107 (42%), Positives = 68/107 (63%)
Frame = +3
Query: 189 DNIEXTEXQEEDGYNVQCLALGQAGGGVDKSKRITTRYMTKYERARVLGTRALQIAMCSP 368
++++ + N++ L + AG + S+R T MTKYE+A V+G RA Q++ +P
Sbjct: 32 EDVDSVNEYSTEEINMEVLEISDAGMKIKASERKTLPRMTKYEKAHVIGVRATQLSAGAP 91
Query: 369 VMVELEGETDPLQIAMKELKHGKIPIIIRRYLPDHSYEDWSIDELII 509
V++ ET+PL IA EL KIP IIRR LPD S+EDW++DEL+I
Sbjct: 92 PFVDIGNETNPLNIANMELSEKKIPFIIRRKLPDSSFEDWAVDELMI 138
>UniRef50_Q7QX02 Cluster: GLP_511_21202_20888; n=2; Giardia
intestinalis|Rep: GLP_511_21202_20888 - Giardia lamblia
ATCC 50803
Length = 104
Score = 97.5 bits (232), Expect = 3e-19
Identities = 46/84 (54%), Positives = 61/84 (72%), Gaps = 3/84 (3%)
Frame = +3
Query: 273 DKSKRITTRYMTKYERARVLGTRALQIAMCSPVMVELE---GETDPLQIAMKELKHGKIP 443
D KRIT RY+TK+E+AR+LGTRA Q++M +P + + G DPL +A +EL + IP
Sbjct: 21 DPDKRITPRYLTKFEQARILGTRAYQLSMGAPAHITITDKGGHLDPLVLARRELANNAIP 80
Query: 444 IIIRRYLPDHSYEDWSIDELIIID 515
IIIRR+LPD +YEDW + EL IID
Sbjct: 81 IIIRRHLPDGTYEDWKLSELHIID 104
>UniRef50_UPI00006CFA18 Cluster: RNA polymerases K / 14 to 18 kDa
subunit family protein; n=1; Tetrahymena thermophila
SB210|Rep: RNA polymerases K / 14 to 18 kDa subunit
family protein - Tetrahymena thermophila SB210
Length = 163
Score = 96.7 bits (230), Expect = 5e-19
Identities = 48/108 (44%), Positives = 69/108 (63%), Gaps = 2/108 (1%)
Frame = +3
Query: 198 EXTEXQEEDGYNVQCLALGQAGGGVDKSK-RITTRYMTKYERARVLGTRALQIAMCSPVM 374
E ++D Y + + + SK ++T ++TKYE+AR++GTRALQIA SP+
Sbjct: 56 ESQSEVDKDEYPEEMVIIKDQDRDQQASKTKVTPPFLTKYEKARIIGTRALQIAQNSPIY 115
Query: 375 VELEGET-DPLQIAMKELKHGKIPIIIRRYLPDHSYEDWSIDELIIID 515
VE + + DP+ IA KE KIP IIRRYLP+ YEDW++DEL ++D
Sbjct: 116 VETDDKDYDPIAIAEKEFVQKKIPFIIRRYLPNKEYEDWALDELEVLD 163
>UniRef50_A2E3F1 Cluster: DNA-directed RNA polymerases I, II, and
III 14.4 kDa polypeptide, putative; n=2; Trichomonas
vaginalis G3|Rep: DNA-directed RNA polymerases I, II,
and III 14.4 kDa polypeptide, putative - Trichomonas
vaginalis G3
Length = 94
Score = 96.7 bits (230), Expect = 5e-19
Identities = 44/76 (57%), Positives = 60/76 (78%)
Frame = +3
Query: 291 TTRYMTKYERARVLGTRALQIAMCSPVMVELEGETDPLQIAMKELKHGKIPIIIRRYLPD 470
TT Y+TKYE+ARVLG RA+QIA +PV +++ E DPL IA +ELK K P+IIRR LPD
Sbjct: 15 TTEYLTKYEKARVLGIRAMQIANGAPVQIDIGSEVDPLNIAEEELKQKKTPLIIRRTLPD 74
Query: 471 HSYEDWSIDELIIIDQ 518
+YED +++ELI+I++
Sbjct: 75 GTYEDVAVNELIVINE 90
>UniRef50_O77315 Cluster: DNA-directed RNA polymerase subunit I,
putative; n=7; Aconoidasida|Rep: DNA-directed RNA
polymerase subunit I, putative - Plasmodium falciparum
(isolate 3D7)
Length = 163
Score = 86.6 bits (205), Expect = 5e-16
Identities = 46/90 (51%), Positives = 60/90 (66%), Gaps = 15/90 (16%)
Frame = +3
Query: 285 RITTRYMTKYERARVLGTRALQIAMCSPVMVELEGETD---------------PLQIAMK 419
RIT+ Y+TKYE+AR++GTRALQI+M +P+ + +E D PL IA K
Sbjct: 73 RITSPYLTKYEKARIIGTRALQISMNAPLTIPIETSNDMINSKNEYDNYLNNDPLVIAEK 132
Query: 420 ELKHGKIPIIIRRYLPDHSYEDWSIDELII 509
EL + IP I+RRYLP+ SYEDW +DELII
Sbjct: 133 ELYNKSIPFILRRYLPNGSYEDWRLDELII 162
>UniRef50_Q3LW93 Cluster: DNA-directed RNA polymerase I, II and III;
n=1; Bigelowiella natans|Rep: DNA-directed RNA
polymerase I, II and III - Bigelowiella natans
(Pedinomonas minutissima) (Chlorarachnion sp.(strain
CCMP 621))
Length = 115
Score = 82.2 bits (194), Expect = 1e-14
Identities = 40/78 (51%), Positives = 56/78 (71%)
Frame = +3
Query: 282 KRITTRYMTKYERARVLGTRALQIAMCSPVMVELEGETDPLQIAMKELKHGKIPIIIRRY 461
KR + +++K+E+A++LG RA QI+ +P V LEGETDPL IA+KE + KIP+ IRRY
Sbjct: 38 KRFSYPFISKFEKAKLLGVRAKQISNGNPPTVPLEGETDPLLIALKEYRENKIPLKIRRY 97
Query: 462 LPDHSYEDWSIDELIIID 515
D SYED+ + EL I+
Sbjct: 98 FSDGSYEDFFVWELADIN 115
>UniRef50_Q6W391 Cluster: Predicted DNA-directed RNA polymerase IIb;
n=1; uncultured crenarchaeote DeepAnt-EC39|Rep:
Predicted DNA-directed RNA polymerase IIb - uncultured
crenarchaeote DeepAnt-EC39
Length = 168
Score = 68.5 bits (160), Expect = 1e-10
Identities = 31/67 (46%), Positives = 51/67 (76%), Gaps = 1/67 (1%)
Frame = +3
Query: 303 MTKYERARVLGTRALQIAMCSPVMVEL-EGETDPLQIAMKELKHGKIPIIIRRYLPDHSY 479
+T++E+AR++G RALQ+++ +PV VE+ + T LQIAM+ELK IPI+I+R LP+ Y
Sbjct: 100 LTRFEKARIMGARALQLSLGAPVFVEIPKNTTTSLQIAMEELKKRVIPIVIKRTLPNQDY 159
Query: 480 EDWSIDE 500
++ +D+
Sbjct: 160 QNIPLDK 166
>UniRef50_Q8PW42 Cluster: DNA-directed RNA polymerase subunit K;
n=2; Methanosarcina|Rep: DNA-directed RNA polymerase
subunit K - Methanosarcina mazei (Methanosarcina frisia)
Length = 83
Score = 67.7 bits (158), Expect = 3e-10
Identities = 35/78 (44%), Positives = 51/78 (65%), Gaps = 2/78 (2%)
Frame = +3
Query: 231 NVQCLALGQAGGGVDKSKR--ITTRYMTKYERARVLGTRALQIAMCSPVMVELEGETDPL 404
N+ C ++ V K K + T++ERAR++G RALQIAM +PV+VE +G DPL
Sbjct: 3 NLSCFSIIGTHRSVFKFKGDLLVKENYTRFERARIVGARALQIAMGAPVLVEDDGRLDPL 62
Query: 405 QIAMKELKHGKIPIIIRR 458
+A++ELK G IPI ++R
Sbjct: 63 GVAIEELKAGVIPITVKR 80
>UniRef50_Q8TV21 Cluster: DNA-directed RNA polymerase subunit
K/omega; n=5; Euryarchaeota|Rep: DNA-directed RNA
polymerase subunit K/omega - Methanopyrus kandleri
Length = 56
Score = 67.3 bits (157), Expect = 3e-10
Identities = 28/52 (53%), Positives = 42/52 (80%)
Frame = +3
Query: 303 MTKYERARVLGTRALQIAMCSPVMVELEGETDPLQIAMKELKHGKIPIIIRR 458
+T++E AR++G RALQIAM SPV+VE+EG+ DPL+IA +E G +P+++ R
Sbjct: 4 LTRFEIARIVGARALQIAMGSPVLVEVEGDEDPLEIAKREFDEGVVPVVVIR 55
>UniRef50_Q84Q45 Cluster: Putative DNA-directed RNA polymerase Iia;
n=2; Oryza sativa (japonica cultivar-group)|Rep:
Putative DNA-directed RNA polymerase Iia - Oryza sativa
subsp. japonica (Rice)
Length = 286
Score = 65.3 bits (152), Expect = 1e-09
Identities = 31/51 (60%), Positives = 39/51 (76%)
Frame = +3
Query: 291 TTRYMTKYERARVLGTRALQIAMCSPVMVELEGETDPLQIAMKELKHGKIP 443
T++YMTKYERAR+L TRALQI+M +PVMVELEG T PL++ E + P
Sbjct: 87 TSKYMTKYERARILSTRALQISMNAPVMVELEGGTYPLEVEALERVYTDCP 137
>UniRef50_A1RWX0 Cluster: RNA polymerase Rpb6; n=1; Thermofilum
pendens Hrk 5|Rep: RNA polymerase Rpb6 - Thermofilum
pendens (strain Hrk 5)
Length = 81
Score = 64.1 bits (149), Expect = 3e-09
Identities = 30/74 (40%), Positives = 53/74 (71%), Gaps = 1/74 (1%)
Frame = +3
Query: 285 RITTRYMTKYERARVLGTRALQIAMCSPVMVELEGE-TDPLQIAMKELKHGKIPIIIRRY 461
+I ++T++ERAR++G RALQI++ +PV++++ E +DP+ IA KEL+ G +PII+ R+
Sbjct: 2 KIGPPWLTRFERARIIGIRALQISLGAPVLIQVSEELSDPITIAEKELELGLLPIIVVRW 61
Query: 462 LPDHSYEDWSIDEL 503
P+ ++ I L
Sbjct: 62 TPEGKIQEIPIKYL 75
>UniRef50_Q9YDJ9 Cluster: DNA-directed RNA polymerase subunit K;
n=2; Aeropyrum pernix|Rep: DNA-directed RNA polymerase
subunit K - Aeropyrum pernix
Length = 89
Score = 63.7 bits (148), Expect = 4e-09
Identities = 31/76 (40%), Positives = 49/76 (64%), Gaps = 2/76 (2%)
Frame = +3
Query: 285 RITTRYMTKYERARVLGTRALQIAMCSPVMVELE--GETDPLQIAMKELKHGKIPIIIRR 458
+I Y+TKYERAR++G RA Q+++ +P +V+ E G +PL IA E+ +G +P+ I R
Sbjct: 2 KIGPPYLTKYERARIIGVRAFQLSIGAPPLVDPERAGSRNPLDIARYEVDNGILPVSIYR 61
Query: 459 YLPDHSYEDWSIDELI 506
YLP + S+ L+
Sbjct: 62 YLPGGGGQSLSLSRLV 77
>UniRef50_Q0W8C8 Cluster: DNA-directed RNA polymerase, subunit K;
n=2; Euryarchaeota|Rep: DNA-directed RNA polymerase,
subunit K - Uncultured methanogenic archaeon RC-I
Length = 88
Score = 62.9 bits (146), Expect = 7e-09
Identities = 28/60 (46%), Positives = 44/60 (73%)
Frame = +3
Query: 279 SKRITTRYMTKYERARVLGTRALQIAMCSPVMVELEGETDPLQIAMKELKHGKIPIIIRR 458
SK I RY T+YERAR++G RALQI+M +PV+ + +P+++A+ EL+ G +PI +R+
Sbjct: 17 SKEIKDRY-TRYERARIIGARALQISMGAPVLAKNPKTVEPIEVALLELEQGLVPITVRK 75
>UniRef50_O29134 Cluster: DNA-directed RNA polymerase subunit K;
n=9; Euryarchaeota|Rep: DNA-directed RNA polymerase
subunit K - Archaeoglobus fulgidus
Length = 75
Score = 62.5 bits (145), Expect = 1e-08
Identities = 27/51 (52%), Positives = 42/51 (82%)
Frame = +3
Query: 306 TKYERARVLGTRALQIAMCSPVMVELEGETDPLQIAMKELKHGKIPIIIRR 458
T++E+AR++G RALQIAM +PV++E + +T+PL+IA++E G IPI +RR
Sbjct: 12 TRFEKARIIGARALQIAMGAPVLIETD-KTEPLEIALEEFNRGVIPITVRR 61
>UniRef50_Q8ZTF9 Cluster: DNA-directed RNA polymerase subunit K;
n=4; Pyrobaculum|Rep: DNA-directed RNA polymerase
subunit K - Pyrobaculum aerophilum
Length = 106
Score = 60.1 bits (139), Expect = 5e-08
Identities = 30/74 (40%), Positives = 49/74 (66%), Gaps = 2/74 (2%)
Frame = +3
Query: 303 MTKYERARVLGTRALQIAMCSPVMVELE--GETDPLQIAMKELKHGKIPIIIRRYLPDHS 476
+TKYE AR++G RALQ+AM + +V+++ G DP+ IAM+EL+ G + II R +PD
Sbjct: 31 LTKYETARIIGARALQLAMGAQPLVDIQEVGSVDPVLIAMEELRRGLLDFIIVREMPDGK 90
Query: 477 YEDWSIDELIIIDQ 518
+ EL+ +++
Sbjct: 91 TMRIRLKELLELER 104
>UniRef50_A0RUC3 Cluster: DNA-directed RNA polymerase, subunit
K/omega; n=1; Cenarchaeum symbiosum|Rep: DNA-directed
RNA polymerase, subunit K/omega - Cenarchaeum symbiosum
Length = 155
Score = 59.3 bits (137), Expect = 9e-08
Identities = 29/72 (40%), Positives = 47/72 (65%), Gaps = 1/72 (1%)
Frame = +3
Query: 273 DKSKRITTRYMTKYERARVLGTRALQIAMCSPVMVELEGET-DPLQIAMKELKHGKIPII 449
DK I +T++E+AR++G RALQ+++ +P +E+ + L IAM EL+ IPI+
Sbjct: 77 DKKILIGPPVLTRFEKARIMGARALQLSLGAPPFIEIPADARTSLDIAMGELEKRIIPIV 136
Query: 450 IRRYLPDHSYED 485
IRR LP+ Y++
Sbjct: 137 IRRVLPNGDYQN 148
>UniRef50_Q6L1M4 Cluster: DNA-directed RNA polymerase subunit K;
n=2; cellular organisms|Rep: DNA-directed RNA polymerase
subunit K - Picrophilus torridus
Length = 60
Score = 57.6 bits (133), Expect = 3e-07
Identities = 26/53 (49%), Positives = 41/53 (77%), Gaps = 1/53 (1%)
Frame = +3
Query: 303 MTKYERARVLGTRALQIAMCSPVMVELEGE-TDPLQIAMKELKHGKIPIIIRR 458
+TK+E+AR++G RALQIAM +PV++++ + DP+ IAM E ++ IPI I+R
Sbjct: 6 LTKFEKARIIGARALQIAMGAPVIIDISPDIIDPIDIAMIEFENNVIPITIKR 58
>UniRef50_Q5UQ32 Cluster: DNA-directed RNA polymerase subunit 6;
n=1; Acanthamoeba polyphaga mimivirus|Rep: DNA-directed
RNA polymerase subunit 6 - Mimivirus
Length = 396
Score = 57.2 bits (132), Expect = 4e-07
Identities = 33/82 (40%), Positives = 46/82 (56%), Gaps = 1/82 (1%)
Frame = +3
Query: 270 VDKSKRITTRYMTKYERARVLGTRALQIAM-CSPVMVELEGETDPLQIAMKELKHGKIPI 446
+ ++R T +T YE R+LGTRA Q P++ +EG P ++A EL
Sbjct: 182 IPDNERETDPILTYYEIVRILGTRAQQFNYGAKPLIKGVEG-MHPAKMAFVELTAKMTSF 240
Query: 447 IIRRYLPDHSYEDWSIDELIII 512
I+RR+LP YEDW IDEL +I
Sbjct: 241 IVRRHLPGKKYEDWRIDELGMI 262
>UniRef50_Q97ZJ9 Cluster: DNA-directed RNA polymerase subunit K;
n=3; Sulfolobus|Rep: DNA-directed RNA polymerase subunit
K - Sulfolobus solfataricus
Length = 95
Score = 55.6 bits (128), Expect = 1e-06
Identities = 26/58 (44%), Positives = 40/58 (68%), Gaps = 2/58 (3%)
Frame = +3
Query: 303 MTKYERARVLGTRALQIAMCSPVMVELE--GETDPLQIAMKELKHGKIPIIIRRYLPD 470
+T+YE ARV+ RALQ+AM +P ++++ TD + IA +E + G +PI IRR LP+
Sbjct: 27 LTRYEIARVISARALQLAMGAPALIDINNLSSTDVISIAEEEFRRGVLPITIRRRLPN 84
>UniRef50_O26148 Cluster: DNA-directed RNA polymerase subunit K;
n=2; Archaea|Rep: DNA-directed RNA polymerase subunit K
- Methanobacterium thermoautotrophicum
Length = 61
Score = 54.8 bits (126), Expect = 2e-06
Identities = 24/57 (42%), Positives = 42/57 (73%)
Frame = +3
Query: 288 ITTRYMTKYERARVLGTRALQIAMCSPVMVELEGETDPLQIAMKELKHGKIPIIIRR 458
+ ++ +T++ERAR++G RALQI+M + +VE++ DP+ IA KEL+ +P+ +RR
Sbjct: 3 MASKKLTRFERARLIGARALQISMGARPLVEIKESLDPVDIARKELEKKVMPLDVRR 59
>UniRef50_A7DMM8 Cluster: RNA polymerase Rpb6; n=1; Candidatus
Nitrosopumilus maritimus SCM1|Rep: RNA polymerase Rpb6 -
Candidatus Nitrosopumilus maritimus SCM1
Length = 182
Score = 54.4 bits (125), Expect = 3e-06
Identities = 26/66 (39%), Positives = 44/66 (66%), Gaps = 1/66 (1%)
Frame = +3
Query: 303 MTKYERARVLGTRALQIAMCSPVMVELEGETD-PLQIAMKELKHGKIPIIIRRYLPDHSY 479
+T++E+AR++G RALQ+++ +P + + L I+M+EL+ IPI IRR LP+ Y
Sbjct: 113 LTRFEKARIMGARALQLSLGAPPFIPIPKTARISLDISMEELEQRVIPITIRRVLPNGDY 172
Query: 480 EDWSID 497
++ ID
Sbjct: 173 QNIPID 178
>UniRef50_Q9HQJ0 Cluster: DNA-directed RNA polymerase subunit K;
n=6; Euryarchaeota|Rep: DNA-directed RNA polymerase
subunit K - Halobacterium salinarium (Halobacterium
halobium)
Length = 60
Score = 50.8 bits (116), Expect = 3e-05
Identities = 21/55 (38%), Positives = 40/55 (72%)
Frame = +3
Query: 294 TRYMTKYERARVLGTRALQIAMCSPVMVELEGETDPLQIAMKELKHGKIPIIIRR 458
+++ ++YE+AR++G RALQ+A +PV+V+ + +T+P+ IA +E +P +RR
Sbjct: 4 SQHFSRYEKARIIGARALQVAYGAPVLVDTD-QTEPILIAAEEYDADALPFTVRR 57
>UniRef50_A3H7H2 Cluster: RNA polymerase Rpb6; n=1; Caldivirga
maquilingensis IC-167|Rep: RNA polymerase Rpb6 -
Caldivirga maquilingensis IC-167
Length = 104
Score = 50.4 bits (115), Expect = 4e-05
Identities = 26/69 (37%), Positives = 43/69 (62%), Gaps = 2/69 (2%)
Frame = +3
Query: 303 MTKYERARVLGTRALQIAMCSPVMVELE--GETDPLQIAMKELKHGKIPIIIRRYLPDHS 476
+TKYE A+++ R Q+ +P +V + G +DP+ IA +ELK G +P II R LP+
Sbjct: 26 ITKYEFAKIIAVRTRQLMDGAPPLVNPKEIGTSDPVAIAFEELKRGLLPFIIIRRLPNGK 85
Query: 477 YEDWSIDEL 503
++++ EL
Sbjct: 86 RVEYTLKEL 94
>UniRef50_UPI00015BAACE Cluster: DNA-directed RNA polymerase,
subunit K; n=1; Ignicoccus hospitalis KIN4/I|Rep:
DNA-directed RNA polymerase, subunit K - Ignicoccus
hospitalis KIN4/I
Length = 97
Score = 47.6 bits (108), Expect = 3e-04
Identities = 21/55 (38%), Positives = 40/55 (72%), Gaps = 2/55 (3%)
Frame = +3
Query: 300 YMTKYERARVLGTRALQIAMCSPVMVELE--GETDPLQIAMKELKHGKIPIIIRR 458
++TK+ERA ++G RALQ+++ +P ++++ + D L IA +EL+ G +PI ++R
Sbjct: 13 HLTKFERAVIVGVRALQLSIGAPPLIDISKLPKRDALIIAREELRRGLLPITVKR 67
>UniRef50_A4YHC6 Cluster: RNA polymerase Rpb6; n=1; Metallosphaera
sedula DSM 5348|Rep: RNA polymerase Rpb6 -
Metallosphaera sedula DSM 5348
Length = 110
Score = 46.0 bits (104), Expect = 9e-04
Identities = 28/73 (38%), Positives = 45/73 (61%), Gaps = 5/73 (6%)
Frame = +3
Query: 303 MTKYERARVLGTRALQIAM-CSPVM----VELEGETDPLQIAMKELKHGKIPIIIRRYLP 467
+T YERAR++ RALQ+AM SP++ LEG + ++IA +E + +PI +RR P
Sbjct: 24 LTSYERARIISARALQLAMGASPLIDVSSTGLEGASS-IRIAEEEFRSNLLPISVRRRFP 82
Query: 468 DHSYEDWSIDELI 506
+ E S+ ++I
Sbjct: 83 NGKVELISVMKII 95
>UniRef50_Q387N1 Cluster: DNA-directed RNA polymerase subunit,
putative; n=3; Trypanosoma|Rep: DNA-directed RNA
polymerase subunit, putative - Trypanosoma brucei
Length = 131
Score = 44.0 bits (99), Expect = 0.004
Identities = 32/93 (34%), Positives = 48/93 (51%), Gaps = 20/93 (21%)
Frame = +3
Query: 285 RITTRYMTKYERARVLGTRALQIAMCSPVMVE-------------LEG-------ETDPL 404
R ++ Y+TKYE AR++G RA QI + V+++ EG DP+
Sbjct: 28 RKSSVYLTKYEVARIIGERARQIVNGTSVLLDSQNGCGTGNSLELAEGCADPFAASVDPI 87
Query: 405 QIAMKELKHGKIPIIIRRYLPDHSYEDWSIDEL 503
I EL G+IP+I+RR PD E+ ++EL
Sbjct: 88 HITKLELLQGRIPMIVRRTWPDGRTENIPVNEL 120
>UniRef50_Q57650 Cluster: DNA-directed RNA polymerase subunit K;
n=6; Methanococcales|Rep: DNA-directed RNA polymerase
subunit K - Methanococcus jannaschii
Length = 57
Score = 43.2 bits (97), Expect = 0.006
Identities = 20/48 (41%), Positives = 35/48 (72%)
Frame = +3
Query: 303 MTKYERARVLGTRALQIAMCSPVMVELEGETDPLQIAMKELKHGKIPI 446
+TK+E AR+LG R+LQI+ + +E + ++ L+IA +E+K GK+P+
Sbjct: 3 LTKFEIARILGARSLQISSGAYATIETKCDSS-LKIAYEEIKQGKVPL 49
>UniRef50_A3BJH4 Cluster: Putative uncharacterized protein; n=3;
Oryza sativa|Rep: Putative uncharacterized protein -
Oryza sativa subsp. japonica (Rice)
Length = 140
Score = 38.7 bits (86), Expect = 0.14
Identities = 18/26 (69%), Positives = 23/26 (88%)
Frame = +3
Query: 342 ALQIAMCSPVMVELEGETDPLQIAMK 419
ALQI+M + VMVEL+GETDPL+I +K
Sbjct: 110 ALQISMNALVMVELDGETDPLEIKIK 135
Score = 35.1 bits (77), Expect = 1.7
Identities = 16/22 (72%), Positives = 20/22 (90%)
Frame = +3
Query: 342 ALQIAMCSPVMVELEGETDPLQ 407
ALQI+M + VMVEL+GETDPL+
Sbjct: 61 ALQISMNALVMVELDGETDPLE 82
>UniRef50_Q4A221 Cluster: Putative uncharacterized protein; n=1;
Emiliania huxleyi virus 86|Rep: Putative uncharacterized
protein - Emiliania huxleyi virus 86
Length = 81
Score = 35.1 bits (77), Expect = 1.7
Identities = 24/71 (33%), Positives = 40/71 (56%)
Frame = +3
Query: 291 TTRYMTKYERARVLGTRALQIAMCSPVMVELEGETDPLQIAMKELKHGKIPIIIRRYLPD 470
T+ Y+T++E AR+ G LQ+ +++ +T Q A+ + + + I+IRR LP
Sbjct: 6 TSSYLTRFELARLAGIVELQLQDNKTSVID-SSKTLHDQ-AVDIVLNKETDIVIRRILPG 63
Query: 471 HSYEDWSIDEL 503
SYED S+ L
Sbjct: 64 DSYEDVSLKTL 74
>UniRef50_Q38000 Cluster: Orf15 protein; n=1; Streptococcus phage
Cp-1|Rep: Orf15 protein - Bacteriophage Cp-1
Length = 288
Score = 34.3 bits (75), Expect = 2.9
Identities = 15/38 (39%), Positives = 22/38 (57%)
Frame = +3
Query: 375 VELEGETDPLQIAMKELKHGKIPIIIRRYLPDHSYEDW 488
V LE E + + A+ EL IP++IRRY+ +DW
Sbjct: 61 VALESELEDYKNALTELLEQLIPLLIRRYMESKEADDW 98
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 559,678,925
Number of Sequences: 1657284
Number of extensions: 9768214
Number of successful extensions: 21525
Number of sequences better than 10.0: 44
Number of HSP's better than 10.0 without gapping: 21010
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 21500
length of database: 575,637,011
effective HSP length: 98
effective length of database: 413,223,179
effective search space used: 55785129165
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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