Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P17_F_B13
(574 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
M60502-1|AAA63248.1| 797|Homo sapiens profilaggrin protein. 34 0.41
M24355-1|AAA52454.1| 416|Homo sapiens FLG protein. 34 0.41
AL356504-1|CAI19595.1| 4061|Homo sapiens filaggrin protein. 34 0.41
AB208881-1|BAD92118.1| 583|Homo sapiens PREDICTED: filaggrin va... 34 0.41
M29581-1|AAA61314.1| 543|Homo sapiens ZNF8 protein. 33 0.71
D87062-1|BAB46918.1| 166|Homo sapiens cerebral protein-3 protein. 32 1.2
BC052266-1|AAH52266.1| 641|Homo sapiens FZD2 protein protein. 31 2.2
AK127273-1|BAC86911.1| 182|Homo sapiens protein ( Homo sapiens ... 31 2.9
BC080554-1|AAH80554.1| 659|Homo sapiens splicing factor, argini... 31 3.8
BC039323-1|AAH39323.1| 575|Homo sapiens zinc finger protein 8 p... 31 3.8
AY358944-1|AAQ89303.1| 594|Homo sapiens SWAP2 protein. 31 3.8
AF042810-1|AAC82340.1| 659|Homo sapiens suppressor of white-apr... 31 3.8
AF042800-1|AAC82339.1| 659|Homo sapiens suppressor of white apr... 31 3.8
AB076353-1|BAD01540.1| 365|Homo sapiens keratin associated prot... 30 5.0
L37882-1|AAB46397.1| 565|Homo sapiens frizzled protein. 30 6.7
BC113404-1|AAI13405.1| 565|Homo sapiens FZD2 protein protein. 30 6.7
BC113402-1|AAI13403.1| 565|Homo sapiens FZD2 protein protein. 30 6.7
AK123974-1|BAC85739.1| 322|Homo sapiens protein ( Homo sapiens ... 30 6.7
AB017364-1|BAA34667.1| 565|Homo sapiens frizzled-2 protein. 30 6.7
>M60502-1|AAA63248.1| 797|Homo sapiens profilaggrin protein.
Length = 797
Score = 33.9 bits (74), Expect = 0.41
Identities = 23/78 (29%), Positives = 31/78 (39%), Gaps = 2/78 (2%)
Frame = -2
Query: 486 NHDGHQRCSLLYVRNHQARRGSS-YHVRHHHRGSRA-GSCGHRCGGQPRSKHSRIWGEHR 313
+H+ HQ + R R GS Y V H + A G G GG+ S+H + R
Sbjct: 424 HHESHQESTRGRSRGRSGRSGSFLYQVSTHEQSESAHGRAGPSTGGRQGSRHEQARDSSR 483
Query: 312 CRGHGRSQEKPRGRWGQR 259
Q+ RG G R
Sbjct: 484 HSASQEGQDTIRGHPGSR 501
>M24355-1|AAA52454.1| 416|Homo sapiens FLG protein.
Length = 416
Score = 33.9 bits (74), Expect = 0.41
Identities = 26/79 (32%), Positives = 35/79 (44%), Gaps = 9/79 (11%)
Frame = -2
Query: 483 HDGHQRCSLLYVRNHQARRGSSYH-VRHHHRGSRAGSCGHRCGGQPRS---KHSRIWG-- 322
H G + S + Q+ GS + RHH SRA S GH GQ +S + SR WG
Sbjct: 119 HSGSRSASRQTRNDEQSGDGSRHSGSRHHEASSRADSSGHSQVGQGQSEGPRTSRNWGSS 178
Query: 321 ---EHRCRGHGRSQEKPRG 274
+ +GH E+ G
Sbjct: 179 FSQDSDSQGHSEDSERWSG 197
>AL356504-1|CAI19595.1| 4061|Homo sapiens filaggrin protein.
Length = 4061
Score = 33.9 bits (74), Expect = 0.41
Identities = 26/79 (32%), Positives = 35/79 (44%), Gaps = 9/79 (11%)
Frame = -2
Query: 483 HDGHQRCSLLYVRNHQARRGSSYH-VRHHHRGSRAGSCGHRCGGQPRS---KHSRIWG-- 322
H G + S + Q+ GS + RHH SRA S GH GQ +S + SR WG
Sbjct: 2507 HSGSRSASRQTRNDEQSGDGSRHSGSRHHEASSRADSSGHSQVGQGQSEGPRTSRNWGSS 2566
Query: 321 ---EHRCRGHGRSQEKPRG 274
+ +GH E+ G
Sbjct: 2567 FSQDSDSQGHSEDSERWSG 2585
>AB208881-1|BAD92118.1| 583|Homo sapiens PREDICTED: filaggrin
variant protein.
Length = 583
Score = 33.9 bits (74), Expect = 0.41
Identities = 26/79 (32%), Positives = 35/79 (44%), Gaps = 9/79 (11%)
Frame = -2
Query: 483 HDGHQRCSLLYVRNHQARRGSSYH-VRHHHRGSRAGSCGHRCGGQPRS---KHSRIWG-- 322
H G + S + Q+ GS + RHH SRA S GH GQ +S + SR WG
Sbjct: 23 HSGSRSASRQTRNDEQSGDGSRHSGSRHHEASSRADSSGHSQVGQGQSEGPRTSRNWGSS 82
Query: 321 ---EHRCRGHGRSQEKPRG 274
+ +GH E+ G
Sbjct: 83 FSQDSDSQGHSEDSERWSG 101
>M29581-1|AAA61314.1| 543|Homo sapiens ZNF8 protein.
Length = 543
Score = 33.1 bits (72), Expect = 0.71
Identities = 15/36 (41%), Positives = 20/36 (55%)
Frame = -2
Query: 447 RNHQARRGSSYHVRHHHRGSRAGSCGHRCGGQPRSK 340
R Q+ +S+ V+H H SR S G R GQP S+
Sbjct: 469 RREQSSSRNSHLVQHQHPNSRKSSAGGRKAGQPESR 504
>D87062-1|BAB46918.1| 166|Homo sapiens cerebral protein-3 protein.
Length = 166
Score = 32.3 bits (70), Expect = 1.2
Identities = 20/69 (28%), Positives = 27/69 (39%)
Frame = -2
Query: 459 LLYVRNHQARRGSSYHVRHHHRGSRAGSCGHRCGGQPRSKHSRIWGEHRCRGHGRSQEKP 280
L +V + R + V H A + H C G PR + WG C G K
Sbjct: 27 LTWVWRRERRCCKVFSVSHCLEAGPAKAWAHSCTGSPRGRTG--WGSRACEALG----KG 80
Query: 279 RGRWGQRGL 253
G WG+ G+
Sbjct: 81 MGLWGRGGM 89
>BC052266-1|AAH52266.1| 641|Homo sapiens FZD2 protein protein.
Length = 641
Score = 31.5 bits (68), Expect = 2.2
Identities = 13/30 (43%), Positives = 19/30 (63%)
Frame = +3
Query: 144 ASSVMMPRHTMPRLITPLLIMPHPLSMQLH 233
A++ M PR +PRL+ PLL++P Q H
Sbjct: 73 AAASMRPRSALPRLLLPLLLLPAAGPAQFH 102
>AK127273-1|BAC86911.1| 182|Homo sapiens protein ( Homo sapiens
cDNA FLJ45340 fis, clone BRHIP3008714. ).
Length = 182
Score = 31.1 bits (67), Expect = 2.9
Identities = 21/78 (26%), Positives = 31/78 (39%), Gaps = 5/78 (6%)
Frame = -3
Query: 221 GQWVRHNEQGRNEPRHSVPGHHDGRCDWDETAAAW-----WYGRRPALAASQHGAKDEHF 57
G+W++ QG++ H V H W + W W P +AA + D
Sbjct: 54 GRWLQGATQGQHSLSHLVDTHEQQLLTWQVLCSGWRPLSDWQVAGPHIAAGRGQEGDRVP 113
Query: 56 GEHFATRETEQVTEHRPA 3
GEH + R V H+ A
Sbjct: 114 GEH-SHRARFHVPPHKHA 130
>BC080554-1|AAH80554.1| 659|Homo sapiens splicing factor,
arginine/serine-rich 16 protein.
Length = 659
Score = 30.7 bits (66), Expect = 3.8
Identities = 22/72 (30%), Positives = 29/72 (40%)
Frame = -2
Query: 486 NHDGHQRCSLLYVRNHQARRGSSYHVRHHHRGSRAGSCGHRCGGQPRSKHSRIWGEHRCR 307
N +R S + +R SS SR G +R G RS+ SR W R R
Sbjct: 355 NASARRRSSSSSSSSSASRTSSSRSSSRSSSRSRRGGGYYRSGRHARSR-SRSWSRSRSR 413
Query: 306 GHGRSQEKPRGR 271
S+ + RGR
Sbjct: 414 SRRYSRSRSRGR 425
>BC039323-1|AAH39323.1| 575|Homo sapiens zinc finger protein 8
protein.
Length = 575
Score = 30.7 bits (66), Expect = 3.8
Identities = 14/36 (38%), Positives = 19/36 (52%)
Frame = -2
Query: 447 RNHQARRGSSYHVRHHHRGSRAGSCGHRCGGQPRSK 340
R Q+ +S+ V+H H SR S G GQP S+
Sbjct: 501 RREQSSSRNSHLVQHQHPNSRKSSAGGAKAGQPESR 536
>AY358944-1|AAQ89303.1| 594|Homo sapiens SWAP2 protein.
Length = 594
Score = 30.7 bits (66), Expect = 3.8
Identities = 22/72 (30%), Positives = 29/72 (40%)
Frame = -2
Query: 486 NHDGHQRCSLLYVRNHQARRGSSYHVRHHHRGSRAGSCGHRCGGQPRSKHSRIWGEHRCR 307
N +R S + +R SS SR G +R G RS+ SR W R R
Sbjct: 370 NASARRRSSSSSSSSSASRTSSSRSSSRSSSRSRRGGGYYRSGRHARSR-SRSWSRSRSR 428
Query: 306 GHGRSQEKPRGR 271
S+ + RGR
Sbjct: 429 SRRYSRSRSRGR 440
>AF042810-1|AAC82340.1| 659|Homo sapiens suppressor of
white-apricot homolog 2 protein.
Length = 659
Score = 30.7 bits (66), Expect = 3.8
Identities = 22/72 (30%), Positives = 29/72 (40%)
Frame = -2
Query: 486 NHDGHQRCSLLYVRNHQARRGSSYHVRHHHRGSRAGSCGHRCGGQPRSKHSRIWGEHRCR 307
N +R S + +R SS SR G +R G RS+ SR W R R
Sbjct: 355 NASARRRSSSSSSSSSASRTSSSRSSSRSSSRSRRGGGYYRSGRHARSR-SRSWSRSRSR 413
Query: 306 GHGRSQEKPRGR 271
S+ + RGR
Sbjct: 414 SRRYSRSRSRGR 425
>AF042800-1|AAC82339.1| 659|Homo sapiens suppressor of white
apricot homolog 2 protein.
Length = 659
Score = 30.7 bits (66), Expect = 3.8
Identities = 22/72 (30%), Positives = 29/72 (40%)
Frame = -2
Query: 486 NHDGHQRCSLLYVRNHQARRGSSYHVRHHHRGSRAGSCGHRCGGQPRSKHSRIWGEHRCR 307
N +R S + +R SS SR G +R G RS+ SR W R R
Sbjct: 355 NASARRRSSSSSSSSSASRTSSSRSSSRSSSRSRRGGGYYRSGRHARSR-SRSWSRSRSR 413
Query: 306 GHGRSQEKPRGR 271
S+ + RGR
Sbjct: 414 SRRYSRSRSRGR 425
>AB076353-1|BAD01540.1| 365|Homo sapiens keratin associated protein
protein.
Length = 365
Score = 30.3 bits (65), Expect = 5.0
Identities = 17/64 (26%), Positives = 25/64 (39%)
Frame = +1
Query: 43 AKCSPKCSSLAPCWLAANAGLLPYHHAAAVSSQSHRPS*CPGTLCLGSLRPCSLCRTHCP 222
+ C P C + +PC A + + S +P+ C + C S LC H
Sbjct: 254 SSCQPACCTSSPCQHACCVPVCSGASTSCCQQSSCQPACCTASCCRSSSSVSLLC--HPV 311
Query: 223 CSST 234
C ST
Sbjct: 312 CKST 315
>L37882-1|AAB46397.1| 565|Homo sapiens frizzled protein.
Length = 565
Score = 29.9 bits (64), Expect = 6.7
Identities = 12/26 (46%), Positives = 16/26 (61%)
Frame = +3
Query: 156 MMPRHTMPRLITPLLIMPHPLSMQLH 233
M PR +PRL+ PLL++P Q H
Sbjct: 1 MRPRSALPRLLLPLLLLPAAGPAQFH 26
>BC113404-1|AAI13405.1| 565|Homo sapiens FZD2 protein protein.
Length = 565
Score = 29.9 bits (64), Expect = 6.7
Identities = 12/26 (46%), Positives = 16/26 (61%)
Frame = +3
Query: 156 MMPRHTMPRLITPLLIMPHPLSMQLH 233
M PR +PRL+ PLL++P Q H
Sbjct: 1 MRPRSALPRLLLPLLLLPAAGPAQFH 26
>BC113402-1|AAI13403.1| 565|Homo sapiens FZD2 protein protein.
Length = 565
Score = 29.9 bits (64), Expect = 6.7
Identities = 12/26 (46%), Positives = 16/26 (61%)
Frame = +3
Query: 156 MMPRHTMPRLITPLLIMPHPLSMQLH 233
M PR +PRL+ PLL++P Q H
Sbjct: 1 MRPRSALPRLLLPLLLLPAAGPAQFH 26
>AK123974-1|BAC85739.1| 322|Homo sapiens protein ( Homo sapiens
cDNA FLJ41980 fis, clone SMINT2007391. ).
Length = 322
Score = 29.9 bits (64), Expect = 6.7
Identities = 17/45 (37%), Positives = 21/45 (46%)
Frame = -2
Query: 396 RGSRAGSCGHRCGGQPRSKHSRIWGEHRCRGHGRSQEKPRGRWGQ 262
RGSR G G R GG + WG R R++ RG WG+
Sbjct: 65 RGSRDGGRGRRGGGVAGQRSQEGWGSGR-----RARVTGRGSWGR 104
>AB017364-1|BAA34667.1| 565|Homo sapiens frizzled-2 protein.
Length = 565
Score = 29.9 bits (64), Expect = 6.7
Identities = 12/26 (46%), Positives = 16/26 (61%)
Frame = +3
Query: 156 MMPRHTMPRLITPLLIMPHPLSMQLH 233
M PR +PRL+ PLL++P Q H
Sbjct: 1 MRPRSALPRLLLPLLLLPAAGPAQFH 26
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 85,089,317
Number of Sequences: 237096
Number of extensions: 2047205
Number of successful extensions: 6606
Number of sequences better than 10.0: 19
Number of HSP's better than 10.0 without gapping: 5959
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6551
length of database: 76,859,062
effective HSP length: 86
effective length of database: 56,468,806
effective search space used: 5872755824
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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