Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P16_pT_P15
(665 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_UPI0000D56743 Cluster: PREDICTED: similar to 3-hydroxyi... 229 6e-59
UniRef50_P31937 Cluster: 3-hydroxyisobutyrate dehydrogenase, mit... 222 5e-57
UniRef50_Q399N0 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=7... 213 4e-54
UniRef50_Q9V8M5 Cluster: Probable 3-hydroxyisobutyrate dehydroge... 212 7e-54
UniRef50_Q54CX6 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3... 208 9e-53
UniRef50_Q7NWA9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=7... 200 3e-50
UniRef50_A7UBP6 Cluster: Putative 3-hydroxyisobutyrate dehydroge... 184 2e-45
UniRef50_Q9A8J9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2... 178 8e-44
UniRef50_Q83D20 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=9... 178 8e-44
UniRef50_P28811 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=7... 177 2e-43
UniRef50_Q0K0E2 Cluster: 3-Hydroxyisobutyrate dehydrogenase; n=1... 175 1e-42
UniRef50_Q22B54 Cluster: 3-hydroxyisobutyrate dehydrogenase fami... 175 1e-42
UniRef50_Q2UHA9 Cluster: Predicted dehydrogenase; n=16; Pezizomy... 171 1e-41
UniRef50_A0QSJ0 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3... 169 5e-41
UniRef50_Q9SUC0 Cluster: Probable 3-hydroxyisobutyrate dehydroge... 162 6e-39
UniRef50_A0C2T7 Cluster: Chromosome undetermined scaffold_145, w... 161 1e-38
UniRef50_P63936 Cluster: Probable 3-hydroxyisobutyrate dehydroge... 161 1e-38
UniRef50_A7JGH8 Cluster: Predicted protein; n=1; Francisella tul... 160 2e-38
UniRef50_Q6C351 Cluster: Yarrowia lipolytica chromosome F of str... 156 4e-37
UniRef50_UPI00015B4162 Cluster: PREDICTED: similar to MGC108315 ... 150 3e-35
UniRef50_Q4PCH4 Cluster: Putative uncharacterized protein; n=1; ... 149 8e-35
UniRef50_A1QPH6 Cluster: 3-hydroxyisobutyrate dehydrogenase mmsB... 142 9e-33
UniRef50_A6NVP0 Cluster: Putative uncharacterized protein; n=1; ... 141 2e-32
UniRef50_Q0QLF5 Cluster: 2-hydroxymethyl glutarate dehydrogenase... 137 2e-31
UniRef50_A3I4V2 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 136 4e-31
UniRef50_Q0URA2 Cluster: Putative uncharacterized protein; n=1; ... 134 2e-30
UniRef50_Q4ZQL5 Cluster: 3-hydroxyisobutyrate dehydrogenase prec... 132 1e-29
UniRef50_A0GVR3 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 130 4e-29
UniRef50_Q67QX0 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 129 5e-29
UniRef50_Q1V2R0 Cluster: MmsB-like protein; n=2; Candidatus Pela... 128 1e-28
UniRef50_A0JUJ6 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2... 128 1e-28
UniRef50_Q1AVA4 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 126 6e-28
UniRef50_A1SIN3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 124 1e-27
UniRef50_Q0C8I2 Cluster: Predicted protein; n=3; Pezizomycotina|... 124 2e-27
UniRef50_A3H5R1 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 122 8e-27
UniRef50_Q55702 Cluster: Uncharacterized oxidoreductase slr0229;... 122 1e-26
UniRef50_Q1QWU9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 120 3e-26
UniRef50_Q8ES28 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 117 2e-25
UniRef50_A0UF54 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 117 2e-25
UniRef50_Q0UVR9 Cluster: Putative uncharacterized protein; n=1; ... 117 3e-25
UniRef50_Q606G9 Cluster: Oxidoreductase, Gfo/Idh/MocA family; n=... 116 5e-25
UniRef50_Q13LQ9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 116 7e-25
UniRef50_O34948 Cluster: Uncharacterized oxidoreductase ykwC; n=... 116 7e-25
UniRef50_A2U9T6 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 115 9e-25
UniRef50_A5V0D4 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 115 1e-24
UniRef50_Q01ZG6 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 114 2e-24
UniRef50_Q0S5S3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 113 3e-24
UniRef50_Q9K9L1 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2... 113 4e-24
UniRef50_Q1GJB9 Cluster: 6-phosphogluconate dehydrogenase NAD-bi... 113 4e-24
UniRef50_Q01QM2 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 113 4e-24
UniRef50_Q9LNP0 Cluster: F1L3.35; n=8; Magnoliophyta|Rep: F1L3.3... 113 4e-24
UniRef50_A3LTC4 Cluster: 3-hydroxyisobutyrate dehydrogenase-like... 113 4e-24
UniRef50_Q4FMJ3 Cluster: 6-phosphogluconate dehydrogenase; n=2; ... 113 5e-24
UniRef50_Q55W03 Cluster: Putative uncharacterized protein; n=2; ... 112 8e-24
UniRef50_Q4Q7T9 Cluster: 2-hydroxy-3-oxopropionate reductase, pu... 111 1e-23
UniRef50_Q97XZ7 Cluster: Oxidoreductase; n=6; Thermoprotei|Rep: ... 111 1e-23
UniRef50_P0ABQ3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 111 1e-23
UniRef50_Q0LNZ7 Cluster: 3-hydroxyisobutyrate dehydrogenase prec... 110 3e-23
UniRef50_Q8KL12 Cluster: Probable 6-phosphogluconate dehydrogena... 109 4e-23
UniRef50_Q930C6 Cluster: Probable; n=8; Alphaproteobacteria|Rep:... 109 6e-23
UniRef50_Q58PL4 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 109 8e-23
UniRef50_A3X9R7 Cluster: 3-hydroxyisobutyrate dehydrogenase fami... 109 8e-23
UniRef50_Q92D17 Cluster: Lin1004 protein; n=10; Bacilli|Rep: Lin... 108 1e-22
UniRef50_Q41DK0 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 108 1e-22
UniRef50_A1UP64 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 108 1e-22
UniRef50_A0LMG6 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=9... 108 1e-22
UniRef50_Q656T5 Cluster: Oxidoreductase-like; n=3; Oryza sativa|... 107 2e-22
UniRef50_Q18X68 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 107 2e-22
UniRef50_Q4KH51 Cluster: 3-hydroxyisobutyrate dehydrogenase fami... 107 3e-22
UniRef50_Q3DYV4 Cluster: NADP oxidoreductase, coenzyme F420-depe... 107 3e-22
UniRef50_Q11FC5 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 106 4e-22
UniRef50_Q0SBQ9 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 106 4e-22
UniRef50_A0N0V2 Cluster: BtdhL; n=1; Azoarcus anaerobius|Rep: Bt... 106 5e-22
UniRef50_A0LDJ3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 105 1e-21
UniRef50_Q9HLR4 Cluster: Putative uncharacterized protein Ta0161... 105 1e-21
UniRef50_Q2BFK1 Cluster: Oxidoreductase; n=1; Bacillus sp. NRRL ... 105 1e-21
UniRef50_A3RRS1 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 105 1e-21
UniRef50_A5GPC0 Cluster: Hydroxyacid dehydrogenase/reductase fam... 104 2e-21
UniRef50_Q13PY3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2... 103 3e-21
UniRef50_Q89UN2 Cluster: Bll1384 protein; n=9; Bacteria|Rep: Bll... 103 4e-21
UniRef50_Q89HA0 Cluster: Oxidoreductase; n=1; Bradyrhizobium jap... 103 5e-21
UniRef50_Q1N6I0 Cluster: Putative oxidoreductase protein; n=1; O... 102 9e-21
UniRef50_A2SP40 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 102 9e-21
UniRef50_Q2JEV5 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 101 1e-20
UniRef50_Q03UI4 Cluster: 3-hydroxyisobutyrate dehydrogenase rela... 101 1e-20
UniRef50_A6SW62 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 101 1e-20
UniRef50_A0FZ96 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 101 1e-20
UniRef50_Q84VC8 Cluster: Gamma hydroxybutyrate dehydrogenase-lik... 101 2e-20
UniRef50_Q97ZE5 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=4... 101 2e-20
UniRef50_Q830A7 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 100 3e-20
UniRef50_Q47AR2 Cluster: NADP oxidoreductase, coenzyme F420-depe... 100 3e-20
UniRef50_A1B741 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3... 100 3e-20
UniRef50_Q5WBB8 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 100 4e-20
UniRef50_Q6UCZ9 Cluster: Predicted oxidoreductase; n=2; environm... 100 4e-20
UniRef50_Q12CU4 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 100 4e-20
UniRef50_Q89R44 Cluster: Oxidoreductase; n=23; Bacteria|Rep: Oxi... 99 5e-20
UniRef50_Q183P5 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 99 5e-20
UniRef50_A0G5F9 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 99 5e-20
UniRef50_Q8U2W2 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 99 5e-20
UniRef50_Q4WXG9 Cluster: 3-hydroxyisobutyrate dehydrogenase, put... 100 6e-20
UniRef50_A0JXR2 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 99 8e-20
UniRef50_Q5L168 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 99 1e-19
UniRef50_A4IN46 Cluster: 3-hydroxyisobutyrate dehydrogenase-like... 99 1e-19
UniRef50_A3SJ77 Cluster: Probable oxidoreductase; n=1; Roseovari... 99 1e-19
UniRef50_Q7WG50 Cluster: Probable oxidoreductase; n=1; Bordetell... 98 1e-19
UniRef50_Q0RCX7 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 98 1e-19
UniRef50_A4SWE8 Cluster: 2-hydroxy-3-oxopropionate reductase pre... 98 1e-19
UniRef50_A3K497 Cluster: Probable 6-phosphogluconate dehydrogena... 98 1e-19
UniRef50_Q3W9W7 Cluster: 6-phosphogluconate dehydrogenase, NAD b... 98 2e-19
UniRef50_Q94B07 Cluster: Gamma hydroxybutyrate dehydrogenase; n=... 97 3e-19
UniRef50_A1WM48 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 97 3e-19
UniRef50_Q39FA8 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 96 6e-19
UniRef50_A3WMG5 Cluster: Probable 3-hydroxyisobutyrate dehydroge... 96 6e-19
UniRef50_A3EW86 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 96 6e-19
UniRef50_Q019Z7 Cluster: Oxidoreductase-like; n=1; Ostreococcus ... 96 6e-19
UniRef50_Q73P00 Cluster: 3-hydroxyacid dehydrogenase family prot... 96 8e-19
UniRef50_A0GI22 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 96 8e-19
UniRef50_Q7VYY0 Cluster: Putative oxidoreductase; n=4; Bordetell... 95 1e-18
UniRef50_A5P0V0 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 95 1e-18
UniRef50_A7PEG7 Cluster: Chromosome chr11 scaffold_13, whole gen... 95 1e-18
UniRef50_A6GTB5 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 95 2e-18
UniRef50_Q1IQE6 Cluster: 2-hydroxy-3-oxopropionate reductase pre... 94 2e-18
UniRef50_P77161 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 94 2e-18
UniRef50_Q0F1Y7 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 94 3e-18
UniRef50_A7IE35 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2... 93 4e-18
UniRef50_Q8PK98 Cluster: 3-hydroxyisobutirate dehydrogenase; n=3... 93 5e-18
UniRef50_Q121N3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 92 1e-17
UniRef50_A1R2J4 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 92 1e-17
UniRef50_A3WAC4 Cluster: Dehydrogenase; n=4; Bacteria|Rep: Dehyd... 91 2e-17
UniRef50_A5FTT0 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 90 4e-17
UniRef50_A6LT11 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 90 5e-17
UniRef50_A6P2M7 Cluster: Putative uncharacterized protein; n=2; ... 89 7e-17
UniRef50_Q46TQ0 Cluster: UDP-glucose/GDP-mannose dehydrogenase:P... 89 9e-17
UniRef50_A6G049 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 89 9e-17
UniRef50_UPI00003C03F8 Cluster: PREDICTED: similar to CG4747-PA;... 89 1e-16
UniRef50_Q7WNK6 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 89 1e-16
UniRef50_Q1QWQ5 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 89 1e-16
UniRef50_A6VYD9 Cluster: 2-hydroxy-3-oxopropionate reductase pre... 89 1e-16
UniRef50_A0K0Z6 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 89 1e-16
UniRef50_Q8TT25 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2... 89 1e-16
UniRef50_UPI0000E49FD0 Cluster: PREDICTED: similar to gamma hydr... 88 2e-16
UniRef50_O33730 Cluster: Uncharacterized oxidoreductase Sfri_150... 88 2e-16
UniRef50_A5VBF0 Cluster: 2-hydroxy-3-oxopropionate reductase pre... 87 3e-16
UniRef50_A2C1U6 Cluster: 3-hydroxyisobutyrate dehydrogenase and ... 87 3e-16
UniRef50_O66454 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3... 87 4e-16
UniRef50_Q9JYH6 Cluster: 3-hydroxyacid dehydrogenase; n=5; Prote... 86 6e-16
UniRef50_A5USN9 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 86 8e-16
UniRef50_A1GFG2 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 85 1e-15
UniRef50_Q0QWD5 Cluster: Putative 3-hydroxyisobutyrate dehydroge... 85 1e-15
UniRef50_A6SUL3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 85 1e-15
UniRef50_Q7WCG3 Cluster: Putative uncharacterized protein; n=2; ... 85 2e-15
UniRef50_Q7NEW9 Cluster: Glr3759 protein; n=3; Bacteria|Rep: Glr... 85 2e-15
UniRef50_Q0FFH2 Cluster: Putative 2-hydroxyacid dehydrogenase; n... 84 3e-15
UniRef50_Q9L7S0 Cluster: Uncharacterized oxidoreductase yihU; n=... 83 4e-15
UniRef50_A6EH53 Cluster: Putative uncharacterized protein; n=1; ... 83 6e-15
UniRef50_A1ZWM5 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 83 6e-15
UniRef50_UPI00015B4B33 Cluster: PREDICTED: similar to 3-hydroxyi... 83 8e-15
UniRef50_UPI0000D55E08 Cluster: PREDICTED: similar to CG4747-PA;... 83 8e-15
UniRef50_Q9RX16 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=6... 83 8e-15
UniRef50_A0G5G5 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 83 8e-15
UniRef50_Q5FQ06 Cluster: Putative oxidoreductase; n=1; Gluconoba... 82 1e-14
UniRef50_Q39MY1 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2... 82 1e-14
UniRef50_Q7Q161 Cluster: ENSANGP00000013149; n=11; Culicidae|Rep... 82 1e-14
UniRef50_A7DSF1 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 82 1e-14
UniRef50_A0LTQ8 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 81 2e-14
UniRef50_Q0BTJ3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 81 2e-14
UniRef50_Q8EW87 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 81 3e-14
UniRef50_A3VLN6 Cluster: Oxidoreductase; n=1; Rhodobacterales ba... 81 3e-14
UniRef50_Q1YHQ4 Cluster: Putative 2-hydroxy-3-oxopropionate redu... 80 5e-14
UniRef50_A0QZR7 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 80 5e-14
UniRef50_A6VLT0 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 79 7e-14
UniRef50_A0QUD5 Cluster: 3-hydroxyisobutyrate dehydrogenase fami... 79 7e-14
UniRef50_Q1EPJ1 Cluster: 6-phosphogluconate dehydrogenase NAD-bi... 79 7e-14
UniRef50_Q9LM23 Cluster: Fructose-bisphosphate aldolase; n=2; Ar... 79 1e-13
UniRef50_Q8VYC5 Cluster: Fructose-bisphosphate aldolase; n=12; c... 79 1e-13
UniRef50_Q49A26 Cluster: Cytokine-like nuclear factor n-pac; n=4... 79 1e-13
UniRef50_A3JU55 Cluster: Predicted dehydrogenase, with NAD(P)-bi... 79 1e-13
UniRef50_A1WJN2 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 79 1e-13
UniRef50_Q89RT2 Cluster: Bll2680 protein; n=1; Bradyrhizobium ja... 78 2e-13
UniRef50_A0R1N4 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 78 2e-13
UniRef50_Q0KC92 Cluster: 3-Hydroxyisobutyrate dehydrogenase; n=1... 77 3e-13
UniRef50_A5VEA3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 77 4e-13
UniRef50_A1UJF2 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 77 4e-13
UniRef50_Q8F4I7 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=4... 76 9e-13
UniRef50_A3ET09 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3... 76 9e-13
UniRef50_A0GPK7 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 76 9e-13
UniRef50_A7I8V1 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 76 9e-13
UniRef50_Q3W3N3 Cluster: Putative uncharacterized protein; n=1; ... 75 1e-12
UniRef50_Q4Q9Z1 Cluster: Dehydrogenase-like protein; n=6; Trypan... 75 2e-12
UniRef50_Q2CHC8 Cluster: Oxidoreductase; n=1; Oceanicola granulo... 75 2e-12
UniRef50_Q12H32 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 75 2e-12
UniRef50_A5WG80 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 75 2e-12
UniRef50_Q5LNV6 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2... 74 3e-12
UniRef50_A0RU56 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 74 4e-12
UniRef50_Q6F842 Cluster: Putative 3-hydroxyisobutyrate dehydroge... 73 8e-12
UniRef50_A1CAY2 Cluster: Oxidoreductase, acting on the CH-OH gro... 73 8e-12
UniRef50_Q8UBW3 Cluster: Oxidoredutase; n=1; Agrobacterium tumef... 72 1e-11
UniRef50_A7DWL2 Cluster: Putative dehydrogenase; n=1; Streptomyc... 72 1e-11
UniRef50_Q20XN2 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 72 1e-11
UniRef50_A7RG59 Cluster: Predicted protein; n=1; Nematostella ve... 72 1e-11
UniRef50_A6F020 Cluster: Putative uncharacterized protein; n=1; ... 70 4e-11
UniRef50_A1SQ87 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 70 6e-11
UniRef50_A4S5A4 Cluster: Predicted protein; n=2; Ostreococcus|Re... 70 6e-11
UniRef50_Q4WV01 Cluster: Oxidoreductase, acting on the CH-OH gro... 70 6e-11
UniRef50_UPI0000EBE4FC Cluster: PREDICTED: hypothetical protein;... 69 8e-11
UniRef50_Q84H84 Cluster: Putative oxidoreductase; n=1; Arthrobac... 69 8e-11
UniRef50_A1WEB7 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 69 8e-11
UniRef50_A0NRG5 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 69 8e-11
UniRef50_A0JRK4 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 69 1e-10
UniRef50_Q21AH6 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 68 2e-10
UniRef50_A3H6C3 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 68 2e-10
UniRef50_Q3W9L4 Cluster: Putative uncharacterized protein; n=1; ... 67 3e-10
UniRef50_Q01PV6 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 67 3e-10
UniRef50_A0K107 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 67 3e-10
UniRef50_Q7NR40 Cluster: Probable 3-hydroxyisobutyrate dehydroge... 67 4e-10
UniRef50_Q5LQR0 Cluster: 6-phosphogluconate dehydrogenase domain... 67 4e-10
UniRef50_A0R1N5 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 67 4e-10
UniRef50_A0YMN9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3... 66 5e-10
UniRef50_UPI0001597301 Cluster: YfjR; n=1; Bacillus amyloliquefa... 66 7e-10
UniRef50_Q3WJ00 Cluster: 6-phosphogluconate dehydrogenase, NAD b... 66 7e-10
UniRef50_A4FKN9 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 66 7e-10
UniRef50_A0VSV4 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 66 7e-10
UniRef50_Q13VQ8 Cluster: Putative dehydrogenase/oxidoreductase p... 66 9e-10
UniRef50_A5P600 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 66 9e-10
UniRef50_A4ECY9 Cluster: Putative uncharacterized protein; n=1; ... 66 9e-10
UniRef50_Q89M84 Cluster: Blr4309 protein; n=6; Bradyrhizobiaceae... 65 2e-09
UniRef50_Q1GF31 Cluster: 6-phosphogluconate dehydrogenase NAD-bi... 65 2e-09
UniRef50_Q98I20 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2... 64 3e-09
UniRef50_P71825 Cluster: Uncharacterized oxidoreductase Rv0770/M... 64 3e-09
UniRef50_Q39KK8 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 64 4e-09
UniRef50_A7H7Z5 Cluster: 6-phosphogluconate dehydrogenase NAD-bi... 62 9e-09
UniRef50_A7CWR7 Cluster: 6-phosphogluconate dehydrogenase NAD-bi... 62 9e-09
UniRef50_A3Y8R5 Cluster: Putative dehydrogenase; n=1; Marinomona... 62 9e-09
UniRef50_A6RMW8 Cluster: Putative uncharacterized protein; n=2; ... 62 9e-09
UniRef50_O34969 Cluster: Uncharacterized oxidoreductase yfjR; n=... 62 9e-09
UniRef50_A5CN67 Cluster: Putative beta-hydroxyacid dehydrogenase... 62 2e-08
UniRef50_Q0RIL5 Cluster: Putative uncharacterized protein; n=1; ... 61 2e-08
UniRef50_Q6RXW5 Cluster: Succinic semialdehyde dehydrogenase; n=... 60 4e-08
UniRef50_Q1B326 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 60 4e-08
UniRef50_A3PRM1 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 60 4e-08
UniRef50_A1UJF3 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 60 4e-08
UniRef50_Q74D68 Cluster: 3-hydroxyisobutyrate dehydrogenase fami... 60 5e-08
UniRef50_Q9I1R8 Cluster: Probable dehydrogenase; n=7; Pseudomona... 60 6e-08
UniRef50_Q221W9 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 59 8e-08
UniRef50_Q1V2K7 Cluster: NADP oxidoreductase, coenzyme F420-depe... 59 1e-07
UniRef50_A6R0U9 Cluster: Predicted protein; n=1; Ajellomyces cap... 59 1e-07
UniRef50_Q8T079 Cluster: LD22344p; n=2; Sophophora|Rep: LD22344p... 58 1e-07
UniRef50_Q98K09 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=7... 58 2e-07
UniRef50_Q5GUM4 Cluster: Dehydrogenase; n=5; Gammaproteobacteria... 57 4e-07
UniRef50_Q2JEN4 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 57 4e-07
UniRef50_Q0RMX6 Cluster: Putative reductase; n=1; Frankia alni A... 55 1e-06
UniRef50_A3ES45 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 55 1e-06
UniRef50_Q5MZU3 Cluster: 3-hydroxyacid dehydrogenase; n=3; Cyano... 54 2e-06
UniRef50_A1WS34 Cluster: Putative uncharacterized protein; n=1; ... 54 2e-06
UniRef50_Q8YRT5 Cluster: 3-hydroxyacid dehydrogenase; n=5; Cyano... 54 3e-06
UniRef50_Q1GM24 Cluster: 6-phosphogluconate dehydrogenase NAD-bi... 54 3e-06
UniRef50_Q1NHG5 Cluster: Putative uncharacterized protein; n=1; ... 54 4e-06
UniRef50_Q21ZT0 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 53 5e-06
UniRef50_A3Q3U7 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 53 5e-06
UniRef50_Q21ZN3 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 52 1e-05
UniRef50_Q9K9H3 Cluster: 6-phosphogluconate dehydrogenase; n=7; ... 52 2e-05
UniRef50_A0AWL7 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 51 2e-05
UniRef50_Q392H4 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 51 3e-05
UniRef50_Q89GM2 Cluster: Bll6323 protein; n=6; Proteobacteria|Re... 50 5e-05
UniRef50_Q629W3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 50 5e-05
UniRef50_A4BV63 Cluster: 3-hydroxyacid dehydrogenase; n=1; Nitro... 50 5e-05
UniRef50_A1C8I6 Cluster: NAD binding NADP oxidoreductase coenzym... 50 5e-05
UniRef50_Q033P2 Cluster: 3-hydroxyisobutyrate dehydrogenase rela... 50 7e-05
UniRef50_A4JSC3 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 50 7e-05
UniRef50_A0FZ97 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 50 7e-05
UniRef50_Q120Q9 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 49 9e-05
UniRef50_Q55JR1 Cluster: Putative uncharacterized protein; n=2; ... 49 1e-04
UniRef50_A5GJY3 Cluster: 3-hydroxyisobutyrate dehydrogenase rela... 48 2e-04
UniRef50_Q6D9X4 Cluster: Putative 2-hydroxy-3-oxopropionate redu... 48 3e-04
UniRef50_Q0SAG5 Cluster: Phosphogluconate dehydrogenase; n=23; A... 47 4e-04
UniRef50_A4EEN1 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 47 4e-04
UniRef50_A3PSD9 Cluster: 6-phosphogluconate dehydrogenase, decar... 47 4e-04
UniRef50_Q0W2D7 Cluster: Putative 6-phosphogluconate dehydrogena... 47 4e-04
UniRef50_UPI0000F1E276 Cluster: PREDICTED: similar to G protein-... 46 8e-04
UniRef50_Q1NHF5 Cluster: Putative oxidoreductase; n=1; Sphingomo... 46 8e-04
UniRef50_Q4WSB8 Cluster: 6-phosphogluconate dehydrogenase family... 46 0.001
UniRef50_Q9RBX6 Cluster: IgiB; n=1; Vogesella indigofera|Rep: Ig... 44 0.003
UniRef50_Q1INE9 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 44 0.003
UniRef50_A6T947 Cluster: Putative dehydrogenase; n=1; Klebsiella... 44 0.004
UniRef50_A3H9B3 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 43 0.006
UniRef50_Q82ZC2 Cluster: 6-phosphogluconate dehydrogenase family... 43 0.008
UniRef50_Q53WI1 Cluster: Putative uncharacterized protein TTHB24... 42 0.010
UniRef50_Q5FU44 Cluster: Putative oxidoreductase; n=1; Gluconoba... 42 0.013
UniRef50_A6ELE2 Cluster: 6-phosphogluconate dehydrogenase, decar... 42 0.018
UniRef50_A5FVG0 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 42 0.018
UniRef50_Q2UET7 Cluster: Predicted protein; n=7; Eurotiomycetida... 41 0.023
UniRef50_Q7TZG1 Cluster: 6-phosphogluconate dehydrogenase, decar... 41 0.031
UniRef50_A1UDJ6 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 41 0.031
UniRef50_O66788 Cluster: 6-phosphogluconate dehydrogenase; n=2; ... 40 0.071
UniRef50_Q9RU02 Cluster: 6-phosphogluconate dehydrogenase; n=24;... 39 0.094
UniRef50_Q8EW86 Cluster: HAD superfamily hydrolase; n=1; Mycopla... 39 0.094
UniRef50_Q0U6Q6 Cluster: Putative uncharacterized protein; n=5; ... 39 0.12
UniRef50_Q836Q9 Cluster: 6-phosphogluconate dehydrogenase, decar... 38 0.16
UniRef50_Q5B0A2 Cluster: Putative uncharacterized protein; n=1; ... 38 0.16
UniRef50_Q9CDN4 Cluster: 6-phosphogluconate dehydrogenase; n=12;... 38 0.22
UniRef50_Q4RNR1 Cluster: Chromosome 2 SCAF15010, whole genome sh... 38 0.29
UniRef50_O32911 Cluster: 6-phosphogluconate dehydrogenase, decar... 38 0.29
UniRef50_P80859 Cluster: 6-phosphogluconate dehydrogenase, decar... 37 0.38
UniRef50_Q9RNC5 Cluster: Putative 3-hydroxyacid dehydrogenase; n... 37 0.50
UniRef50_Q9YE14 Cluster: Putative dehydrogenase; n=1; Aeropyrum ... 36 0.66
UniRef50_Q0V6D4 Cluster: Putative uncharacterized protein; n=1; ... 36 0.88
UniRef50_UPI0000EBD7FD Cluster: PREDICTED: hypothetical protein;... 36 1.2
UniRef50_Q19TN0 Cluster: 3-hydroxyisobutyrate dehydrogenase fami... 36 1.2
UniRef50_Q9F3P6 Cluster: Putative dehydrogenase; n=1; Streptomyc... 35 2.0
UniRef50_Q1DDR1 Cluster: 6-phosphogluconate dehydrogenase, decar... 35 2.0
UniRef50_Q1AZK2 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 34 2.7
UniRef50_A5BSQ5 Cluster: Putative uncharacterized protein; n=1; ... 34 2.7
UniRef50_P37754 Cluster: 6-phosphogluconate dehydrogenase, decar... 34 3.5
UniRef50_P21577 Cluster: 6-phosphogluconate dehydrogenase, decar... 33 4.7
UniRef50_UPI0000E81355 Cluster: PREDICTED: hypothetical protein;... 33 8.2
UniRef50_Q0F1E8 Cluster: Putative uncharacterized protein; n=1; ... 33 8.2
UniRef50_A6PRE0 Cluster: MATE efflux family protein; n=1; Victiv... 33 8.2
>UniRef50_UPI0000D56743 Cluster: PREDICTED: similar to
3-hydroxyisobutyrate dehydrogenase; n=1; Tribolium
castaneum|Rep: PREDICTED: similar to
3-hydroxyisobutyrate dehydrogenase - Tribolium castaneum
Length = 315
Score = 229 bits (559), Expect = 6e-59
Identities = 108/210 (51%), Positives = 138/210 (65%)
Frame = -3
Query: 657 HAKKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKED 478
HA KGSL ID STI P V +++ G F DAPVSGGV GA+ TL FM GG K+
Sbjct: 104 HASKGSLLIDCSTIQPQVAQEVSKATYSAGFKFLDAPVSGGVTGAEAGTLTFMVGGDKQV 163
Query: 477 FERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLL 298
+ P+L MGA HCG G+GQ+AKL NN+++ IT + T E MN+GIKMGL+PK L
Sbjct: 164 LNSADPILMKMGANVLHCGDSGAGQIAKLCNNLILAITMIGTCEGMNLGIKMGLDPKTLA 223
Query: 297 DVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIP 118
++N S+ RSWS++ Y PVPGL+ P S +Y GGF L+ KDL LA G+AL +P+P
Sbjct: 224 SIINVSTGRSWSSQTYNPVPGLIEKIPPSNDYKGGFAVNLVAKDLGLAEGVALLCNAPVP 283
Query: 117 LGAVATQLYRIVQSRGYGQKDFSFVFQLLK 28
L A A Q+YR + GYG KDF+ V+Q LK
Sbjct: 284 LTAAAHQIYRALSCNGYGNKDFASVYQFLK 313
>UniRef50_P31937 Cluster: 3-hydroxyisobutyrate dehydrogenase,
mitochondrial precursor; n=38; Eumetazoa|Rep:
3-hydroxyisobutyrate dehydrogenase, mitochondrial
precursor - Homo sapiens (Human)
Length = 336
Score = 222 bits (543), Expect = 5e-57
Identities = 106/211 (50%), Positives = 145/211 (68%)
Frame = -3
Query: 651 KKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFE 472
KKGSL IDSSTIDP V K++ + G F DAPVSGGV A++ L FM GG +++F
Sbjct: 124 KKGSLLIDSSTIDPAVSKELAKEVEKMGAVFMDAPVSGGVGAARSGNLTFMVGGVEDEFA 183
Query: 471 RSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDV 292
+ LL MG+ +CG +G+GQ AK+ NNML+ I+ + TAE MN+GI++GL+PK+L +
Sbjct: 184 AAQELLGCMGSNVVYCGAVGTGQAAKICNNMLLAISMIGTAEAMNLGIRLGLDPKLLAKI 243
Query: 291 LNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLG 112
LN SS R WS++ Y PVPG++ PS+ NY GGF LM KDL LA A +SPI LG
Sbjct: 244 LNMSSGRCWSSDTYNPVPGVMDGVPSANNYQGGFGTTLMAKDLGLAQDSATSTKSPILLG 303
Query: 111 AVATQLYRIVQSRGYGQKDFSFVFQLLKRRK 19
++A Q+YR++ ++GY +KDFS VFQ L+ +
Sbjct: 304 SLAHQIYRMMCAKGYSKKDFSSVFQFLREEE 334
>UniRef50_Q399N0 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=72;
cellular organisms|Rep: 3-hydroxyisobutyrate
dehydrogenase - Burkholderia sp. (strain 383)
(Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 /
R18194))
Length = 299
Score = 213 bits (519), Expect = 4e-54
Identities = 104/211 (49%), Positives = 137/211 (64%)
Frame = -3
Query: 645 GSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERS 466
G+ IDSSTIDP + + E G F DAPVSGG GA TL FM GG DFER
Sbjct: 87 GATVIDSSTIDPASAQAFGALVREHGGAFVDAPVSGGTGGAAAGTLTFMVGGSDADFERV 146
Query: 465 LPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLN 286
P+L MG HCG G GQVAK+ NN+++GI+ A +E M++G+ +G++PKVL ++N
Sbjct: 147 KPVLAGMGKNIVHCGATGMGQVAKVCNNLVLGISMAAVSEAMSLGVALGIDPKVLAGIVN 206
Query: 285 NSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAV 106
S+ R WS++ Y P PG++ TAPSSR Y GGF +LM+KDL LA+ A R P+ LGA+
Sbjct: 207 TSTGRCWSSDTYNPYPGVIDTAPSSRGYSGGFGTDLMLKDLGLANDAAKQARQPVYLGAL 266
Query: 105 ATQLYRIVQSRGYGQKDFSFVFQLLKRRKQK 13
A QLY+ + SRG GQ DFS V +L + +K
Sbjct: 267 AQQLYQTMSSRGDGQLDFSAVIRLYQPATKK 297
>UniRef50_Q9V8M5 Cluster: Probable 3-hydroxyisobutyrate
dehydrogenase, mitochondrial precursor; n=4;
Diptera|Rep: Probable 3-hydroxyisobutyrate
dehydrogenase, mitochondrial precursor - Drosophila
melanogaster (Fruit fly)
Length = 324
Score = 212 bits (517), Expect = 7e-54
Identities = 97/210 (46%), Positives = 143/210 (68%)
Frame = -3
Query: 648 KGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFER 469
K ++ IDSSTI P++ K + KG F DAPVSGGV GA+ ATL FM GG + ++
Sbjct: 112 KDTIFIDSSTISPDLVKSLQKKISAKGARFIDAPVSGGVPGAEQATLTFMVGGTEAEYNA 171
Query: 468 SLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVL 289
+L+ MG K HCG G GQ AKL NNM++ I+ + +E MN+ ++ GL+ V +++
Sbjct: 172 VKAVLECMGKKITHCGVYGMGQAAKLCNNMMLAISMIGVSEAMNLAVRQGLDANVFAEII 231
Query: 288 NNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGA 109
N+S+ R W++E+Y PVPG+ P+AP++R+Y GGF + L+ KDL LASG+A SPIPLG+
Sbjct: 232 NSSTGRCWASEIYNPVPGVCPSAPANRDYAGGFSSALITKDLGLASGVANASNSPIPLGS 291
Query: 108 VATQLYRIVQSRGYGQKDFSFVFQLLKRRK 19
+A ++Y+ + +G G KDFS V+ L+K+ K
Sbjct: 292 LAHKVYQSLCDKGLGNKDFSVVYDLMKKEK 321
>UniRef50_Q54CX6 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3;
cellular organisms|Rep: 3-hydroxyisobutyrate
dehydrogenase - Dictyostelium discoideum AX4
Length = 321
Score = 208 bits (508), Expect = 9e-53
Identities = 97/209 (46%), Positives = 138/209 (66%)
Frame = -3
Query: 651 KKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFE 472
+ G+L +DSSTIDP +++ IA + D PVSGG GA+ TL FM GG ++DF
Sbjct: 107 RPGTLLLDSSTIDPATAREVASIAKKHQSTMLDCPVSGGTGGAEAGTLTFMVGGSEQDFN 166
Query: 471 RSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDV 292
+ L+ MG HCG +G+GQVAK+ NN+++GI+ +A +E MN+G+K G++PK L +
Sbjct: 167 TAKTYLECMGKNIVHCGDVGTGQVAKVCNNLVLGISMIAVSEAMNLGVKQGMDPKKLAGI 226
Query: 291 LNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLG 112
N SSAR W++E+Y P PG++ T+P+SR Y GGF + LM KDL LA A I P+ LG
Sbjct: 227 FNTSSARCWTSELYNPCPGVIETSPASRGYTGGFGSALMTKDLGLAVDSAKSIGEPLLLG 286
Query: 111 AVATQLYRIVQSRGYGQKDFSFVFQLLKR 25
A QLY ++ ++G GQKDFS V+ L +
Sbjct: 287 NSAHQLYTLLVAKGDGQKDFSVVYDFLNK 315
>UniRef50_Q7NWA9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=7;
Proteobacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Chromobacterium violaceum
Length = 296
Score = 200 bits (487), Expect = 3e-50
Identities = 99/206 (48%), Positives = 131/206 (63%)
Frame = -3
Query: 660 AHAKKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKE 481
A KG+L ID STID +++ A EKGL DAPVSGG GA TL F+ GG E
Sbjct: 83 ARLPKGALVIDCSTIDAGTARKVAEGAREKGLSMLDAPVSGGTAGAAAGTLTFIVGGAAE 142
Query: 480 DFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVL 301
D + P+L+ MG FH G G+GQ AK+ NNML+GI TAE + +G+K GL+PKVL
Sbjct: 143 DLAHARPVLEAMGKNIFHAGGAGAGQTAKICNNMLLGILMAGTAEALALGVKNGLDPKVL 202
Query: 300 LDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPI 121
++++ SS R+W+TE+Y P PG++ P+SR Y GGF +ELM+KDL LA AL +
Sbjct: 203 SEIISKSSGRNWATELYNPWPGVMDNTPASRGYAGGFMSELMLKDLGLAEETALQSHAAN 262
Query: 120 PLGAVATQLYRIVQSRGYGQKDFSFV 43
PLGA+A LY +G G+ DFS +
Sbjct: 263 PLGALARNLYEEHVHQGNGKLDFSSI 288
>UniRef50_A7UBP6 Cluster: Putative 3-hydroxyisobutyrate
dehydrogenase; n=1; Paracoccus methylutens|Rep: Putative
3-hydroxyisobutyrate dehydrogenase - Paracoccus
methylutens
Length = 302
Score = 184 bits (448), Expect = 2e-45
Identities = 91/212 (42%), Positives = 133/212 (62%)
Frame = -3
Query: 663 VAHAKKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRK 484
+A KGS+ IDSSTID +++ E+G+ DAPVSGGVMGA+ TL FM GG
Sbjct: 82 LAKMAKGSMAIDSSTIDTADARRLHAAGRERGIAVLDAPVSGGVMGAEAGTLTFMVGGSA 141
Query: 483 EDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKV 304
ED ER+ P+L+ MG + FH G+ G GQ AKL NN+L GI+ +A +E + +GL+ +
Sbjct: 142 EDLERARPVLEAMGRRIFHAGEPGVGQAAKLCNNLLAGISMIAVSEAFALARHLGLDARK 201
Query: 303 LLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSP 124
+ ++ S+ +S Y PVPGLVP PSSR Y GF ++LM+KDL+LA A+ +
Sbjct: 202 MQEISAVSTGGCFSLTNYPPVPGLVPNVPSSREYRNGFASQLMLKDLKLAQQAAIQSGTA 261
Query: 123 IPLGAVATQLYRIVQSRGYGQKDFSFVFQLLK 28
+PLG +A LY + G+ + D+S + +L++
Sbjct: 262 LPLGGLAAALYGMFCQAGHSELDYSAIIKLIE 293
>UniRef50_Q9A8J9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=24;
Alphaproteobacteria|Rep: 3-hydroxyisobutyrate
dehydrogenase - Caulobacter crescentus (Caulobacter
vibrioides)
Length = 298
Score = 178 bits (434), Expect = 8e-44
Identities = 89/212 (41%), Positives = 122/212 (57%)
Frame = -3
Query: 657 HAKKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKED 478
+A K +L ID STID + + + A E G F DAPVSGG+M A+ TLAFM G D
Sbjct: 82 NAPKSALLIDCSTIDVDSARVVARQAAEAGFRFADAPVSGGIMAAEAGTLAFMVGCEASD 141
Query: 477 FERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLL 298
F L M H G G+GQ AK+ NNML+G++ + T E + K+GL
Sbjct: 142 FAAVEAALAPMSRVTIHAGDHGAGQAAKICNNMLLGVSMLGTCEAFALAEKLGLAADRFF 201
Query: 297 DVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIP 118
++ + SS + WS YCPVPG+ P P+ R Y+GGF + +M+KDL+LA A + P
Sbjct: 202 EIASKSSGQCWSITSYCPVPGVGPQTPADRGYEGGFASAMMLKDLKLAQEAAAKAGASTP 261
Query: 117 LGAVATQLYRIVQSRGYGQKDFSFVFQLLKRR 22
+GA A LY + + G+G KDFS V +LL+ R
Sbjct: 262 MGAQAEALYALFDANGFGGKDFSAVIELLRGR 293
>UniRef50_Q83D20 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=9;
Proteobacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Coxiella burnetii
Length = 297
Score = 178 bits (434), Expect = 8e-44
Identities = 87/215 (40%), Positives = 131/215 (60%)
Frame = -3
Query: 660 AHAKKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKE 481
A + ++ IDSS+ID +++ A ++G+ DAPVSGGV A+ A L FM GG KE
Sbjct: 83 ATINRQAIYIDSSSIDIEGSRELHKEAKKRGISMLDAPVSGGVAAAEAAGLTFMVGGEKE 142
Query: 480 DFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVL 301
DFER+ +L ++G K + G G+G AK+ NNML+GI+ +A +E + K+GL+P+ L
Sbjct: 143 DFERAKRVLGILGKKIIYAGSDGAGAAAKICNNMLLGISMIAVSEAFVLADKLGLDPQKL 202
Query: 300 LDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPI 121
++ +N+S WS YCP PG++ PSS Y GF ++M+KDL L+ A ++
Sbjct: 203 FEISSNASGECWSLTHYCPWPGILKDVPSSHEYKPGFTAKMMLKDLNLSQAAASDAKANT 262
Query: 120 PLGAVATQLYRIVQSRGYGQKDFSFVFQLLKRRKQ 16
PLG AT+LY+ +G+ DFS + LLK + Q
Sbjct: 263 PLGKRATELYQQFVDSDHGEVDFSAIINLLKDKSQ 297
>UniRef50_P28811 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=72;
Proteobacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Pseudomonas aeruginosa
Length = 298
Score = 177 bits (431), Expect = 2e-43
Identities = 88/185 (47%), Positives = 119/185 (64%)
Frame = -3
Query: 639 LXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLP 460
L ID STI P +++ A KGL DAPVSGGV GA+ TL+F+ GG E F R+ P
Sbjct: 90 LLIDCSTIAPETARKVAEAAAAKGLTLLDAPVSGGVGGARAGTLSFIVGGPAEGFARARP 149
Query: 459 LLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNS 280
+L+ MG FH G G+GQVAK+ NNML+GI TAE + +G+K GL+P VL +V+ S
Sbjct: 150 VLENMGRNIFHAGDHGAGQVAKICNNMLLGILMAGTAEALALGVKNGLDPAVLSEVMKQS 209
Query: 279 SARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAT 100
S +W+ +Y P PG++P AP+S Y GGF+ LM KDL LA A +++ PLGA+A
Sbjct: 210 SGGNWALNLYNPWPGVMPQAPASNGYAGGFQVRLMNKDLGLALANAQAVQASTPLGALAR 269
Query: 99 QLYRI 85
L+ +
Sbjct: 270 NLFSL 274
>UniRef50_Q0K0E2 Cluster: 3-Hydroxyisobutyrate dehydrogenase; n=1;
Ralstonia eutropha H16|Rep: 3-Hydroxyisobutyrate
dehydrogenase - Ralstonia eutropha (strain ATCC 17699 /
H16 / DSM 428 / Stanier 337)(Cupriavidus necator (strain
ATCC 17699 / H16 / DSM 428 / Stanier337))
Length = 299
Score = 175 bits (425), Expect = 1e-42
Identities = 82/209 (39%), Positives = 130/209 (62%)
Frame = -3
Query: 654 AKKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDF 475
A G+L I+SSTI P + + A + G DAPV+GG GA+ A L FM GG + F
Sbjct: 85 AAPGALLIESSTIGPAAARAVAAEAAQAGFAMLDAPVAGGQAGAREARLTFMVGGARTAF 144
Query: 474 ERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLD 295
+R+ P+L+ MGA+ F+ G G+GQ+AKL NN++ ++ +E +G K+G++ + + D
Sbjct: 145 DRAEPVLRQMGARIFYAGASGNGQIAKLCNNLIACVSSAVVSEAFILGSKLGMDYQTMYD 204
Query: 294 VLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPL 115
++ S+ + W+ CPVPG VP++P+SR+Y GF +LM+KDL L + A + + P
Sbjct: 205 IITQSTGQCWTLSHNCPVPGPVPSSPASRDYVPGFAADLMLKDLSLVASAASEVGAATPF 264
Query: 114 GAVATQLYRIVQSRGYGQKDFSFVFQLLK 28
GA A QLYR + G G +D++ V +L++
Sbjct: 265 GARAIQLYRQLSESGLGARDWTVVARLIE 293
>UniRef50_Q22B54 Cluster: 3-hydroxyisobutyrate dehydrogenase family
protein; n=1; Tetrahymena thermophila SB210|Rep:
3-hydroxyisobutyrate dehydrogenase family protein -
Tetrahymena thermophila SB210
Length = 316
Score = 175 bits (425), Expect = 1e-42
Identities = 91/213 (42%), Positives = 131/213 (61%), Gaps = 1/213 (0%)
Frame = -3
Query: 648 KGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGR-KEDFE 472
K SL IDSSTI + +I+ A + + DAPVSGGV A TL FM G KE F+
Sbjct: 103 KNSLFIDSSTISYHAAIKIYENAKKVNQRYIDAPVSGGVGAATAGTLTFMVGAENKELFQ 162
Query: 471 RSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDV 292
LL+ MG +C + G+G +AK+ NNM +GI +A AE +++G K+G++PKVL +
Sbjct: 163 ECKNLLQHMGKNIANCEKPGAGSIAKICNNMALGIEMIAVAEAISLGKKLGIDPKVLSSI 222
Query: 291 LNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLG 112
+N +S R WS+EVY P PG++ P+S+ Y+GGF ELM+KDL LA+ A + +PLG
Sbjct: 223 MNTASGRCWSSEVYNPCPGVLENVPASKGYEGGFACELMLKDLGLAADAAKQASADVPLG 282
Query: 111 AVATQLYRIVQSRGYGQKDFSFVFQLLKRRKQK 13
A +Y+ + G +KDF+ V+ +L K K
Sbjct: 283 NHAKDIYQKLVELGLNRKDFAIVYDVLLNNKLK 315
>UniRef50_Q2UHA9 Cluster: Predicted dehydrogenase; n=16;
Pezizomycotina|Rep: Predicted dehydrogenase -
Aspergillus oryzae
Length = 363
Score = 171 bits (416), Expect = 1e-41
Identities = 97/214 (45%), Positives = 130/214 (60%), Gaps = 4/214 (1%)
Frame = -3
Query: 651 KKGSLXIDSSTIDPNVPKQIFPIALEKGLG-FTDAPVSGGVMGAQNATLAFMAGGRKEDF 475
+K L ID+STIDP ++I G F DAP+SGGV+GA+ TL+FM G +
Sbjct: 146 EKERLFIDTSTIDPASSREIANAIHTTRQGRFVDAPMSGGVVGARAGTLSFMFGASSQTG 205
Query: 474 E---RSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKV 304
E R +L +MG K +H G G+G AKL NN L+ I +ATAE MN+GI+ GL+PKV
Sbjct: 206 ELVDRVQSVLMLMGKKAWHMGNSGTGVSAKLANNYLLAINNIATAEVMNLGIRCGLDPKV 265
Query: 303 LLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSP 124
L D++N S+ R W E+ PVPG+V TAP+SR Y GGF LM KDL LA A +P
Sbjct: 266 LADMINTSTGRCWPMEINNPVPGVVETAPASREYAGGFGISLMNKDLRLAISAAEESGTP 325
Query: 123 IPLGAVATQLYRIVQSRGYGQKDFSFVFQLLKRR 22
+ L A +Y+ V+ G KDFS V++ L+ +
Sbjct: 326 LALADKARGVYKAVEDEHRG-KDFSVVYKWLQEQ 358
>UniRef50_A0QSJ0 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3;
Bacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
Length = 290
Score = 169 bits (411), Expect = 5e-41
Identities = 88/209 (42%), Positives = 119/209 (56%)
Frame = -3
Query: 654 AKKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDF 475
A G+L ID+STI + + + ALEKG DAPVSGGV GA TLAFM GG +
Sbjct: 82 APTGTLFIDTSTISVDDARTVHTQALEKGHAQLDAPVSGGVKGATAGTLAFMVGGEDDAV 141
Query: 474 ERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLD 295
ER+ P+L M K HCG G+GQ AKL NNM++ + +A E + K+GL + L D
Sbjct: 142 ERARPILDPMAGKIIHCGGSGTGQAAKLCNNMVLAVQQIAIGEAFVLAEKLGLSAQSLFD 201
Query: 294 VLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPL 115
V+ ++ WS CPVPG VPT+P++ ++ GF LM KDL LA + PL
Sbjct: 202 VITGATGNCWSVHTNCPVPGPVPTSPANNDFKPGFATSLMNKDLGLAMAAVSSTGASAPL 261
Query: 114 GAVATQLYRIVQSRGYGQKDFSFVFQLLK 28
G+ A ++Y + KDFS V +LL+
Sbjct: 262 GSHAAEIYAKFNEE-HADKDFSAVIELLR 289
>UniRef50_Q9SUC0 Cluster: Probable 3-hydroxyisobutyrate
dehydrogenase, mitochondrial precursor; n=13;
Magnoliophyta|Rep: Probable 3-hydroxyisobutyrate
dehydrogenase, mitochondrial precursor - Arabidopsis
thaliana (Mouse-ear cress)
Length = 347
Score = 162 bits (394), Expect = 6e-39
Identities = 84/212 (39%), Positives = 125/212 (58%), Gaps = 10/212 (4%)
Frame = -3
Query: 642 SLXIDSSTIDPNVPKQIFPIALEKGLG----------FTDAPVSGGVMGAQNATLAFMAG 493
+L IDSSTIDP ++I L DAPVSGGV+ A+ TL FM G
Sbjct: 127 ALFIDSSTIDPQTTRKISLAVSNCNLKEKRDNWEKPVMLDAPVSGGVLAAEAGTLTFMVG 186
Query: 492 GRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLE 313
G ++ + + P+L+ MG +CG G+G AK+ NN+ M ++ + T+E + +G +G+
Sbjct: 187 GPEDAYLAARPILQSMGRTSIYCGGSGNGSAAKICNNLAMAVSMLGTSEALALGQSLGIS 246
Query: 312 PKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGI 133
L +VLN SS R WS++ Y PVPG++ PSSR+Y+GGF ++LM KDL LA+ A +
Sbjct: 247 ASTLTEVLNTSSGRCWSSDAYNPVPGVMKGVPSSRDYNGGFASKLMAKDLNLAAASAEEV 306
Query: 132 RSPIPLGAVATQLYRIVQSRGYGQKDFSFVFQ 37
PL + A ++Y+ + G+ KDFS VF+
Sbjct: 307 GHKSPLISKAQEIYKKMCEEGHETKDFSCVFR 338
>UniRef50_A0C2T7 Cluster: Chromosome undetermined scaffold_145,
whole genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_145,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 299
Score = 161 bits (392), Expect = 1e-38
Identities = 81/211 (38%), Positives = 126/211 (59%)
Frame = -3
Query: 651 KKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFE 472
K + IDSSTI P ++ +A + + DAPVSG V A+ T+ FM G KE +E
Sbjct: 90 KSKKILIDSSTISPYTSYELAKMAQDTQNIYADAPVSGSVSEAKLGTITFMVGAEKELYE 149
Query: 471 RSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDV 292
+ P+LK MG F+CG+IG GQ+AK+ NM + I ++ E + +G MG++P +L +
Sbjct: 150 KISPILKEMGKNIFNCGKIGEGQIAKMCGNMALAIQMISVCEALALGKNMGMDPAMLSSI 209
Query: 291 LNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLG 112
++ SS+R W+ + Y P PG++P PS+++YDGGF ELM+KDL + + + LG
Sbjct: 210 MSVSSSRCWTVDTYNPAPGVMPNVPSNKDYDGGFMVELMLKDLGIGIEASRLSGTDTQLG 269
Query: 111 AVATQLYRIVQSRGYGQKDFSFVFQLLKRRK 19
A Q+Y + G+KDF+ V++ L + K
Sbjct: 270 QHAYQIYNKLNEH-LGKKDFAIVYKELIKCK 299
>UniRef50_P63936 Cluster: Probable 3-hydroxyisobutyrate
dehydrogenase; n=25; Bacteria|Rep: Probable
3-hydroxyisobutyrate dehydrogenase - Mycobacterium bovis
Length = 294
Score = 161 bits (391), Expect = 1e-38
Identities = 84/214 (39%), Positives = 120/214 (56%)
Frame = -3
Query: 663 VAHAKKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRK 484
+A A+ +L IDSSTI +++ +A G+ DAPVSGGV GA ATLAFM GG +
Sbjct: 79 LAAARPATLFIDSSTISVTDAREVHALAESHGMLQLDAPVSGGVKGAAAATLAFMVGGDE 138
Query: 483 EDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKV 304
R+ P+L+ M K HCG G+GQ AK+ NNM++ + +A AE + K+GL +
Sbjct: 139 STLRRARPVLEPMAGKIIHCGAAGAGQAAKVCNNMVLAVQQIAIAEAFVLAEKLGLSAQS 198
Query: 303 LLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSP 124
L DV+ ++ W+ CPVPG VPT+P++ ++ GF LM KDL LA +
Sbjct: 199 LFDVITGATGNCWAVHTNCPVPGPVPTSPANNDFKPGFSTALMNKDLGLAMDAVAATGAT 258
Query: 123 IPLGAVATQLYRIVQSRGYGQKDFSFVFQLLKRR 22
PLG+ A +Y + + DFS V L+ R
Sbjct: 259 APLGSHAADIYAKF-AADHADLDFSAVIHTLRAR 291
>UniRef50_A7JGH8 Cluster: Predicted protein; n=1; Francisella
tularensis subsp. novicida GA99-3549|Rep: Predicted
protein - Francisella tularensis subsp. novicida
GA99-3549
Length = 293
Score = 160 bits (389), Expect = 2e-38
Identities = 83/208 (39%), Positives = 119/208 (57%), Gaps = 1/208 (0%)
Frame = -3
Query: 654 AKKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDF 475
AK G++ ID+STID N + A + L DAPVSGG++GAQNATL FM GG KE F
Sbjct: 85 AKAGTIIIDTSTIDANTSVLLAKKAKQNNLHMLDAPVSGGIIGAQNATLTFMVGGDKEIF 144
Query: 474 ERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLD 295
ER L MG K H G G G + KL NNML+GI +A +E N K G+ K D
Sbjct: 145 ERCKNLFNSMGKKYLHVGDNGKGLIIKLINNMLLGINMIAASEACNFAEKTGINLKTFYD 204
Query: 294 VLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPL 115
++ +S+ SW+ P+P ++ P++ +Y GF L++KD+ +A A + L
Sbjct: 205 IVASSTGSSWAFNKNFPMPDIIENVPANNDYKPGFGAPLIMKDINIAVETAQDYNINLKL 264
Query: 114 GAVATQLY-RIVQSRGYGQKDFSFVFQL 34
G +A ++Y R++ S +KDFS V ++
Sbjct: 265 GLLAKEIYERMINSEELNKKDFSAVIKV 292
>UniRef50_Q6C351 Cluster: Yarrowia lipolytica chromosome F of strain
CLIB122 of Yarrowia lipolytica; n=1; Yarrowia
lipolytica|Rep: Yarrowia lipolytica chromosome F of
strain CLIB122 of Yarrowia lipolytica - Yarrowia
lipolytica (Candida lipolytica)
Length = 334
Score = 156 bits (379), Expect = 4e-37
Identities = 87/218 (39%), Positives = 127/218 (58%), Gaps = 6/218 (2%)
Frame = -3
Query: 651 KKGSLXIDSSTIDPNVPKQIFPIALEK--GLGFTDAPVSGGVMGAQNATLAFMAGGRKED 478
K + +D STID + + +K F DAPVSGGV+GA+ TL FM G K+
Sbjct: 117 KTSKIFVDCSTIDTQTSIECGKLVTDKDASAAFVDAPVSGGVVGAEKGTLTFMVGCNKDK 176
Query: 477 ---FERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPK 307
+++ LLK+MG + +CG G G AKL NN L+ +T +ATAE ++ K+G + K
Sbjct: 177 QQVYKQVEELLKLMGGRIVNCGTQGQGLAAKLANNYLLAVTNVATAEAFHLAEKLGCDLK 236
Query: 306 VLLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRS 127
+ D++N+SS RSWS+EV PVPG+ P PSSR+Y GGF LM KDL LA +A S
Sbjct: 237 LFSDIVNSSSGRSWSSEVNNPVPGVNPATPSSRDYVGGFGINLMRKDLGLAIDVAKQSGS 296
Query: 126 PIPLGAVATQLYR-IVQSRGYGQKDFSFVFQLLKRRKQ 16
+ + ++Y+ I + Y KD S +++ L+ + Q
Sbjct: 297 SMLVADKTYEVYQNIEKGDNYQGKDMSVIYKFLQDQDQ 334
>UniRef50_UPI00015B4162 Cluster: PREDICTED: similar to MGC108315
protein; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to MGC108315 protein - Nasonia vitripennis
Length = 276
Score = 150 bits (364), Expect = 3e-35
Identities = 67/142 (47%), Positives = 96/142 (67%)
Frame = -3
Query: 438 KQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWST 259
K HCG G GQVAK+ NNML+ I+ + +E +++G K+GL+PK+L D++N S+ R WS+
Sbjct: 134 KAVHCGDTGMGQVAKICNNMLLAISMIGVSEALSLGEKLGLDPKILTDIVNTSTGRCWSS 193
Query: 258 EVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVATQLYRIVQ 79
EV PVPG+ PT PSS +Y GGF L+ KDL LA A +SPI LG+++ Q+YR ++
Sbjct: 194 EVNNPVPGISPTVPSSNDYAGGFGTSLIAKDLGLAQAAATRAKSPIALGSLSHQIYRTME 253
Query: 78 SRGYGQKDFSFVFQLLKRRKQK 13
+ G G KDFS V+ ++ K
Sbjct: 254 AHGLGGKDFSVVYPFIRGENVK 275
Score = 35.1 bits (77), Expect = 1.5
Identities = 14/28 (50%), Positives = 21/28 (75%)
Frame = -3
Query: 663 VAHAKKGSLXIDSSTIDPNVPKQIFPIA 580
++ AKKG+ +DSSTIDP+V + +F A
Sbjct: 105 ISSAKKGTFLVDSSTIDPSVSQTVFKAA 132
>UniRef50_Q4PCH4 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 366
Score = 149 bits (360), Expect = 8e-35
Identities = 85/221 (38%), Positives = 122/221 (55%), Gaps = 10/221 (4%)
Frame = -3
Query: 663 VAHAKKGSLXIDSSTIDPNVPKQ----IFPIALEKGLGFTDAPVSGGVMGAQNATLAFMA 496
V A+ +L ID +T+DP+V Q I DAPVSGGV+GA ATL+FM
Sbjct: 130 VDDAQAKTLCIDCTTLDPDVAVQTATAIKNANANGAFDMIDAPVSGGVVGANAATLSFMV 189
Query: 495 GGRKED-FERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMG 319
G F + P L +MG++ HCG+ G+G +AK+ NN+L+GI+ + E M +G G
Sbjct: 190 GSDSSTTFASAEPYLSLMGSRAVHCGKNGNGLIAKIANNLLLGISMLGVTEAMLLGTAHG 249
Query: 318 LEPKVLLDVLNNSSARSWSTEVYCPVPGLVP----TAPSSRNYDGGFKNELMVKDLELAS 151
L P VL ++N S+ + WS+EV P PG + + P+ R+Y GGF LM KDL+LA
Sbjct: 250 LPPAVLAGIINTSTGKCWSSEVNNPCPGALEGTKYSPPADRDYQGGFAARLMAKDLKLAM 309
Query: 150 GMALGIRSPIPLGAVATQLYRIVQSRG-YGQKDFSFVFQLL 31
A P PLG + + +Y + + KDF+ F+ L
Sbjct: 310 NTAKLQGVPTPLGQLTSSIYEALGGNDEFKDKDFAVAFKAL 350
>UniRef50_A1QPH6 Cluster: 3-hydroxyisobutyrate dehydrogenase mmsB;
n=5; Mycobacterium|Rep: 3-hydroxyisobutyrate
dehydrogenase mmsB - Mycobacterium tuberculosis (strain
F11)
Length = 315
Score = 142 bits (343), Expect = 9e-33
Identities = 68/163 (41%), Positives = 98/163 (60%)
Frame = -3
Query: 663 VAHAKKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRK 484
+A A+ +L IDSSTI +++ +A G+ DAPVSGGV GA ATLAFM GG +
Sbjct: 79 LAAARPATLFIDSSTISVTDAREVHALAESHGMLQLDAPVSGGVKGAAAATLAFMVGGDE 138
Query: 483 EDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKV 304
R+ P+L+ M K HCG G+GQ AK+ NNM++ + +A AE + K+GL +
Sbjct: 139 STLRRARPVLEPMAGKIIHCGAAGAGQAAKVCNNMVLAVQQIAIAEAFVLAEKLGLSAQS 198
Query: 303 LLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELM 175
L DV+ ++ W+ CPVPG VPT+P++ ++ GF LM
Sbjct: 199 LFDVITGATGNCWAVHTNCPVPGPVPTSPANNDFKPGFSTALM 241
>UniRef50_A6NVP0 Cluster: Putative uncharacterized protein; n=1;
Bacteroides capillosus ATCC 29799|Rep: Putative
uncharacterized protein - Bacteroides capillosus ATCC
29799
Length = 306
Score = 141 bits (341), Expect = 2e-32
Identities = 72/208 (34%), Positives = 118/208 (56%)
Frame = -3
Query: 657 HAKKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKED 478
+ K+G++ ID S++ PN K + A EKG+ + DAPVSGGV GA TL M G E
Sbjct: 88 NCKEGTVIIDMSSVAPNTTKAMAKKAAEKGIHYIDAPVSGGVSGAAAGTLTIMVGADDET 147
Query: 477 FERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLL 298
F + P+ V+G +H G+ G G K+ NN+L+G A AE + +G+K GL + +
Sbjct: 148 FNKVKPIFDVLGKNIYHVGEAGGGDAIKMVNNLLLGCNMAALAEALTLGVKCGLSVETMK 207
Query: 297 DVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIP 118
+V++ SS RS++ + + + ++GGF +L KDL LA + + P+P
Sbjct: 208 EVISVSSGRSYALD------AKLEKFIMAGQFNGGFAVDLQYKDLGLALEASRDEKVPLP 261
Query: 117 LGAVATQLYRIVQSRGYGQKDFSFVFQL 34
+ A A Q+Y + +++G G++D S V ++
Sbjct: 262 MTAAAVQVYEMARAKGQGREDMSSVVKV 289
>UniRef50_Q0QLF5 Cluster: 2-hydroxymethyl glutarate dehydrogenase;
n=1; Eubacterium barkeri|Rep: 2-hydroxymethyl glutarate
dehydrogenase - Eubacterium barkeri (Clostridium
barkeri)
Length = 301
Score = 137 bits (332), Expect = 2e-31
Identities = 70/206 (33%), Positives = 118/206 (57%)
Frame = -3
Query: 651 KKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFE 472
K G++ +D S++ P+ ++ +A EKG+ + DAPVSGG GA+ TL M G + FE
Sbjct: 89 KAGTVIVDMSSVSPSSTLKMAKVAAEKGIDYVDAPVSGGTKGAEAGTLTIMVGASEAVFE 148
Query: 471 RSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDV 292
+ P+L V+G +H G G+G K+ NN+L+G + AE + +G+K GL+P+ + ++
Sbjct: 149 KIQPVLSVIGKDIYHVGDTGAGDAVKIVNNLLLGCNMASLAEALVLGVKCGLKPETMQEI 208
Query: 291 LNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLG 112
+ SS RS++ E + S ++ GGF +L KDL LA P+P+
Sbjct: 209 IGKSSGRSYAME------AKMEKFIMSGDFAGGFAMDLQHKDLGLALEAGKEGNVPLPMT 262
Query: 111 AVATQLYRIVQSRGYGQKDFSFVFQL 34
A+ATQ++ ++ G G++D S V ++
Sbjct: 263 AMATQIFEGGRAMGLGREDMSAVIKV 288
>UniRef50_A3I4V2 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Bacillus sp. B14905|Rep: 3-hydroxyisobutyrate
dehydrogenase - Bacillus sp. B14905
Length = 316
Score = 136 bits (329), Expect = 4e-31
Identities = 78/213 (36%), Positives = 118/213 (55%), Gaps = 1/213 (0%)
Frame = -3
Query: 663 VAHAKKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRK 484
+ HAKKG+L +D ST++P++ + A GL + APVSGGV+GA NATL M GG K
Sbjct: 102 IHHAKKGALLVDFSTVNPDLNDSLHKEASTLGLRYLGAPVSGGVIGAVNATLTIMVGGGK 161
Query: 483 EDFERSLPLLKVMGAKQFHCGQIGS-GQVAKLTNNMLMGITGMATAECMNMGIKMGLEPK 307
+D++ + + ++G +H G S G KL NN+++G A AE + +G KMG++
Sbjct: 162 DDYDSASEIFGIVGKNIYHLGLSSSVGTRLKLLNNLMIGFYTEAVAETIVLGEKMGIDAD 221
Query: 306 VLLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRS 127
L +VL+NS +S +Y + NY GF L++KDL+LA GMA
Sbjct: 222 TLYEVLSNSYGQS---RIY---ERNYVEYMKNNNYAPGFSTNLLLKDLKLAKGMADEAGV 275
Query: 126 PIPLGAVATQLYRIVQSRGYGQKDFSFVFQLLK 28
+ +G +LY + +GYG+ D S + LK
Sbjct: 276 SLRIGEKLVELYSEIAQQGYGENDMSAAYLSLK 308
>UniRef50_Q0URA2 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 325
Score = 134 bits (324), Expect = 2e-30
Identities = 86/211 (40%), Positives = 113/211 (53%), Gaps = 4/211 (1%)
Frame = -3
Query: 633 IDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGR-KEDFERSLPL 457
I++STI V K + L F DAPVSGG MGAQ+ TLAFMAG K F R
Sbjct: 116 IETSTI-LEVAKATSSSKAAENLTFVDAPVSGGPMGAQDGTLAFMAGANNKAIFPRVKGY 174
Query: 456 LKVMGAKQ--FHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNN 283
L MG F CG IG+G K+ NN L IT +A +E +N+G KMGL+ +L DV+N
Sbjct: 175 LSHMGKPDAIFLCGDIGAGTAFKVINNYLSAITSLAASEALNIGTKMGLDVALLTDVINV 234
Query: 282 SSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVA 103
S + W T PVPG+ PSSR+Y+GGF+ EL K L + S +A + + L
Sbjct: 235 SGGQCWVTSKSNPVPGVQANVPSSRDYEGGFRIELCRKVLGMGSELAEMVGARTILDKPT 294
Query: 102 TQLYRIVQSRG-YGQKDFSFVFQLLKRRKQK 13
+ S G Y KD V++ L ++K
Sbjct: 295 LAAFDEAMSDGRYKGKDARVVYKWLNESERK 325
>UniRef50_Q4ZQL5 Cluster: 3-hydroxyisobutyrate dehydrogenase
precursor; n=11; Proteobacteria|Rep:
3-hydroxyisobutyrate dehydrogenase precursor -
Pseudomonas syringae pv. syringae (strain B728a)
Length = 296
Score = 132 bits (318), Expect = 1e-29
Identities = 71/205 (34%), Positives = 113/205 (55%)
Frame = -3
Query: 651 KKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFE 472
+KG + +D++T P + +++ + G+ F DAPVSGG GA +++ + G D
Sbjct: 87 RKGLIVVDTTTSTPEMSRKVAAELAKNGIAFIDAPVSGGPKGAATGSMSMVIGAEDADLA 146
Query: 471 RSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDV 292
R++P+L+ M + H GQ G+G VAK+ NNML ++TAE + M + G++P+ LL
Sbjct: 147 RAMPVLEGMSGTRVHVGQCGAGNVAKIANNMLAACHLISTAEAVAMAARAGVDPEKLLQG 206
Query: 291 LNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLG 112
LN S RS +T+V + PT ++ YD GF LM KD+ LAS +A + +PL
Sbjct: 207 LNAGSGRSGATQV------MFPTWVLNKAYDSGFTMGLMRKDVGLASDLADSLDMDLPLS 260
Query: 111 AVATQLYRIVQSRGYGQKDFSFVFQ 37
V QL++ +DF + Q
Sbjct: 261 RVVAQLWQASSETLADNEDFCAIVQ 285
>UniRef50_A0GVR3 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Burkholderia phytofirmans PsJN|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Burkholderia phytofirmans PsJN
Length = 311
Score = 130 bits (313), Expect = 4e-29
Identities = 68/187 (36%), Positives = 103/187 (55%), Gaps = 1/187 (0%)
Frame = -3
Query: 642 SLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERSL 463
+L ++ ST+D +++ A G DAP++GG+ GA ATL FM GG +E E +
Sbjct: 88 TLLLECSTVDVKTIERLGEGARASGTQLIDAPLTGGIEGAALATLTFMVGGSEEQLEYAR 147
Query: 462 PLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNN 283
P L+ MG++ H G+ GSG KL NNM+ M +E + +G+K+GL+ + + DV+ N
Sbjct: 148 PALQSMGSRIVHAGRFGSGTKLKLVNNMICATNLMVASEALTLGLKLGLDAQPMYDVIAN 207
Query: 282 SSARSWSTEVYCPVPGLVPTAPSSRNYD-GGFKNELMVKDLELASGMALGIRSPIPLGAV 106
+ SW Y P+PG+V APSSR + F M KD+ A A + + PL V
Sbjct: 208 GTGASWVLNTYYPLPGVVDGAPSSRGFRMPTFPATGMAKDMRCALEAARSVEAVTPLHNV 267
Query: 105 ATQLYRI 85
A L ++
Sbjct: 268 AESLLKL 274
>UniRef50_Q67QX0 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Symbiobacterium thermophilum|Rep: 3-hydroxyisobutyrate
dehydrogenase - Symbiobacterium thermophilum
Length = 294
Score = 129 bits (312), Expect = 5e-29
Identities = 76/200 (38%), Positives = 109/200 (54%)
Frame = -3
Query: 654 AKKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDF 475
A+ G + +D STI K+I + EKG+ F DAPVSGG GA+ TL M GG + F
Sbjct: 83 AQPGDIFVDHSTIGVRDAKRIAAMCAEKGVQFIDAPVSGGPWGAEAGTLTIMCGGDRAAF 142
Query: 474 ERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLD 295
E LP L+V G H G +G+G VAKL NN+L+GI A AE +G K G++PK L +
Sbjct: 143 EAVLPYLQVEGKAIHHLGPVGAGSVAKLCNNLLVGIHTAAMAEAFVLGTKAGVDPKALYE 202
Query: 294 VLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPL 115
+++N++ S ++ +P V P +D F + + KD+ LA + + L
Sbjct: 203 IISNATGH--SAQIARNIPQFV--FPG--KFDAAFSIDHLHKDVALAVELGKDENVRMVL 256
Query: 114 GAVATQLYRIVQSRGYGQKD 55
GAV QL ++ GYG D
Sbjct: 257 GAVTQQLLAEARALGYGGSD 276
>UniRef50_Q1V2R0 Cluster: MmsB-like protein; n=2; Candidatus
Pelagibacter ubique|Rep: MmsB-like protein - Candidatus
Pelagibacter ubique HTCC1002
Length = 308
Score = 128 bits (309), Expect = 1e-28
Identities = 68/206 (33%), Positives = 109/206 (52%)
Frame = -3
Query: 648 KGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFER 469
K L ID STID ++ + + G+ DAPV+GGVMGA+ L F+ GG E
Sbjct: 88 KECLIIDCSTIDIETSLELGNESKKLGIKMIDAPVTGGVMGARIGKLNFLVGGSDEAVAL 147
Query: 468 SLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVL 289
+ PL +MG K H G GSG K+ NNM +GI+ +A +E + + ++ ++ K + +++
Sbjct: 148 AKPLFDIMGQKILHAGVQGSGVGVKICNNMSLGISMIAASESLMLAKRLKMDIKKVHEII 207
Query: 288 NNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGA 109
+S +W+ Y P+P L PS+ Y GF +M KDL LA A + + PLG
Sbjct: 208 KAASGNNWAMTNYTPLPNLTDGVPSNNKYRPGFTASMMRKDLRLAMDAAQSVDASTPLGK 267
Query: 108 VATQLYRIVQSRGYGQKDFSFVFQLL 31
A +++ G D+S + +++
Sbjct: 268 AALEIFSKFCDEGDSDTDYSGISKMI 293
>UniRef50_A0JUJ6 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2;
Micrococcineae|Rep: 3-hydroxyisobutyrate dehydrogenase -
Arthrobacter sp. (strain FB24)
Length = 300
Score = 128 bits (309), Expect = 1e-28
Identities = 72/211 (34%), Positives = 113/211 (53%)
Frame = -3
Query: 663 VAHAKKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRK 484
+AHA + +L +DSSTID + + A G F DAPVSGG+ GA+ TL FM GG
Sbjct: 82 LAHADRRTLLVDSSTIDIASAQALHDAAAAAGFRFVDAPVSGGMSGAKAGTLTFMIGGDA 141
Query: 483 EDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKV 304
+ ++ M + G +GQ AK+ NN+++ I +TAE + ++GL+ +V
Sbjct: 142 GAVAEATEYIRPMASNIIPTGGPTTGQAAKICNNLMLFINLASTAEGAVLAERLGLDKQV 201
Query: 303 LLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSP 124
D+ + SS SW+ + PV G+VPTA S+ ++ F EL KD+ LA A +P
Sbjct: 202 FWDIASVSSGDSWALRTWYPVGGVVPTAASNNDFAPTFTTELANKDIGLAISAARDTGTP 261
Query: 123 IPLGAVATQLYRIVQSRGYGQKDFSFVFQLL 31
+ +G L++ + G KD S + +L+
Sbjct: 262 LEIGEHVQTLFQRLIDSGQSGKDCSMIIKLV 292
>UniRef50_Q1AVA4 Cluster: 2-hydroxy-3-oxopropionate reductase; n=6;
Bacteria|Rep: 2-hydroxy-3-oxopropionate reductase -
Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 309
Score = 126 bits (303), Expect = 6e-28
Identities = 74/208 (35%), Positives = 113/208 (54%)
Frame = -3
Query: 651 KKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFE 472
++GSL ID STI P V +Q+ A E+G DAPVSGG +GA+ TL+ M GG +EDF
Sbjct: 100 REGSLLIDMSTISPAVARQLAAKARERGASMLDAPVSGGDVGAREGTLSIMVGGSEEDFG 159
Query: 471 RSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDV 292
R+ PL +VMG H G G+GQ+ K N +++G+T A E + +G++ G+EP+ + +V
Sbjct: 160 RARPLFEVMGKTVTHVGPSGAGQIVKAANQIVVGLTIEAVCEALVLGLRGGVEPQKIFEV 219
Query: 291 LNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLG 112
L A + EV SR++ G K KDL +A +P
Sbjct: 220 LCGGLAANRVMEV-------KREKFLSRDFRPGGKARFHRKDLGIALNTGREYGVALPAA 272
Query: 111 AVATQLYRIVQSRGYGQKDFSFVFQLLK 28
A+ QL+ ++++G G D S + L++
Sbjct: 273 ALVEQLFGALEAKGRGDLDHSALLLLVE 300
>UniRef50_A1SIN3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Nocardioides sp. JS614|Rep: 3-hydroxyisobutyrate
dehydrogenase - Nocardioides sp. (strain BAA-499 /
JS614)
Length = 308
Score = 124 bits (300), Expect = 1e-27
Identities = 69/189 (36%), Positives = 98/189 (51%), Gaps = 1/189 (0%)
Frame = -3
Query: 645 GSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERS 466
G+L IDSS+ID + A G+ F DAPVSGGV GA TL FM GG + R+
Sbjct: 91 GALVIDSSSIDVANCLAVHESAASAGIAFLDAPVSGGVGGAAAGTLTFMVGGDEAHVRRA 150
Query: 465 LPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLN 286
PL + MG K G +GQ K+ N M+ + +A AE ++ K+G+ PK+L +V+
Sbjct: 151 WPLFEAMGKKVVRVGGPSTGQAVKMCNQMIYASSLVAVAEAFSLADKLGVAPKMLFEVVT 210
Query: 285 NSSARSWSTEVYCPVPGLVP-TAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGA 109
+SS W+ CP P +V + + + F + LM KDL LA+ A + P+PL
Sbjct: 211 SSSGDCWAIRNSCPWPDVVEGGSAADEGFAPRFSSRLMSKDLRLATSAASNVGQPLPLTG 270
Query: 108 VATQLYRIV 82
Y V
Sbjct: 271 KTVTFYEKV 279
>UniRef50_Q0C8I2 Cluster: Predicted protein; n=3;
Pezizomycotina|Rep: Predicted protein - Aspergillus
terreus (strain NIH 2624)
Length = 320
Score = 124 bits (299), Expect = 2e-27
Identities = 75/189 (39%), Positives = 106/189 (56%), Gaps = 6/189 (3%)
Frame = -3
Query: 639 LXIDSSTIDP--NVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERS 466
L ID STID ++ + F DAPVSGGV+GAQ +AF G K D +
Sbjct: 102 LLIDCSTIDTATSLAVKAHITTHHASASFYDAPVSGGVLGAQKGAIAFFLGCAKTD--PN 159
Query: 465 LPLL----KVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLL 298
LPLL ++MG + CG G AKL NN L G+ +A +E +N+G++ GL+P+VL
Sbjct: 160 LPLLTDTLRLMGKEVIPCGGPSLGLSAKLCNNYLSGLIAIANSEALNIGMRAGLDPRVLS 219
Query: 297 DVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIP 118
V +A++ + + P PG+VP APSS++Y GFK +LM KD LA MA + + +
Sbjct: 220 SVFAAGTAQNAICDRFNPCPGVVPDAPSSKDYRTGFKIQLMRKDFALAVAMAEQVGARLV 279
Query: 117 LGAVATQLY 91
LG + Y
Sbjct: 280 LGEAGLKTY 288
>UniRef50_A3H5R1 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Caldivirga maquilingensis IC-167|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Caldivirga maquilingensis IC-167
Length = 295
Score = 122 bits (294), Expect = 8e-27
Identities = 77/211 (36%), Positives = 116/211 (54%), Gaps = 1/211 (0%)
Frame = -3
Query: 651 KKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFE 472
K+GSL I+ STI P+ ++ EKG DAP+ G + + + GG +E +E
Sbjct: 87 KQGSLVIEMSTISPSTSIELANKIKEKGGLMVDAPIIGTSILIEKREAVVLIGGEREAYE 146
Query: 471 RSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDV 292
R+ ++K H G G G AKL NN L+G A AE +N+G MGL V++DV
Sbjct: 147 RAYEVVKHFARYVVHVGPNGYGLYAKLINNALLGSYVAALAEVVNLGEAMGLSSSVIMDV 206
Query: 291 LNN-SSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPL 115
L SSARS ++E+ VP ++ + ++ F + M KDL+L + A + P+P+
Sbjct: 207 LTKLSSARSPTSEL--KVPKMI-----NNDFTTQFATKHMRKDLDLVNKEASRLGVPVPM 259
Query: 114 GAVATQLYRIVQSRGYGQKDFSFVFQLLKRR 22
A+A QLYR+ ++ G DFS V ++LKRR
Sbjct: 260 AALALQLYRMSEADGLSDDDFSAVIKILKRR 290
>UniRef50_Q55702 Cluster: Uncharacterized oxidoreductase slr0229;
n=4; Cyanobacteria|Rep: Uncharacterized oxidoreductase
slr0229 - Synechocystis sp. (strain PCC 6803)
Length = 290
Score = 122 bits (293), Expect = 1e-26
Identities = 73/196 (37%), Positives = 106/196 (54%)
Frame = -3
Query: 657 HAKKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKED 478
+AK +L ID STI ++ +GL F DAPV+GG +GA N TL M GG D
Sbjct: 88 YAKPQALIIDCSTIGKTAAYELATNLKLQGLRFLDAPVTGGDVGAINGTLTIMVGGDISD 147
Query: 477 FERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLL 298
FE +LP+LK +G K HCG GSGQ KL N +L GI +A AE + + ++G+ P++++
Sbjct: 148 FEEALPVLKSIGEKIVHCGPSGSGQAVKLCNQVLCGIHAIAAAEAIQLSEQLGIAPELVI 207
Query: 297 DVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIP 118
D + +A SW+ + L P S ++ GF + ++KDL L A P+P
Sbjct: 208 DTCGSGAAGSWA------LTNLAPKM-SEADFAPGFMVKHLLKDLRLVREAA--ENGPLP 258
Query: 117 LGAVATQLYRIVQSRG 70
+A L+ VQ G
Sbjct: 259 GVTLAESLFTSVQLLG 274
>UniRef50_Q1QWU9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Chromohalobacter salexigens DSM 3043|Rep:
3-hydroxyisobutyrate dehydrogenase - Chromohalobacter
salexigens (strain DSM 3043 / ATCC BAA-138 / NCIMB13768)
Length = 310
Score = 120 bits (289), Expect = 3e-26
Identities = 71/180 (39%), Positives = 95/180 (52%)
Frame = -3
Query: 654 AKKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDF 475
A KGS+ +D+ST DP V +++ +E GL + DAPVSGG GA + L + GG
Sbjct: 92 APKGSVIVDTSTSDPAVTRELAGKVVEAGLEWLDAPVSGGPAGAASGALGMLLGGESATI 151
Query: 474 ERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLD 295
ER P+L+ M A+ H G GSG V KL NN L + TAE + + + G++P L
Sbjct: 152 ERLAPMLEAMSARHTHVGPAGSGHVVKLANNYLCAAHLLTTAEAVTLAARAGVDPAACLA 211
Query: 294 VLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPL 115
LN+ S RS +EV P L S +D GF LM KDL LA A + P+ L
Sbjct: 212 GLNSGSGRSAVSEVNFPKWIL------SDAFDSGFTTGLMRKDLRLARDAASNMGLPLEL 265
>UniRef50_Q8ES28 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=13;
Bacillaceae|Rep: 3-hydroxyisobutyrate dehydrogenase -
Oceanobacillus iheyensis
Length = 299
Score = 117 bits (282), Expect = 2e-25
Identities = 67/211 (31%), Positives = 112/211 (53%), Gaps = 1/211 (0%)
Frame = -3
Query: 657 HAKKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKED 478
H + ID+ST+ P + +Q+ E+ + F APVSGGV+GA+N TL M GG++E
Sbjct: 84 HCNSSQVVIDTSTVAPELNQQLEASLSERSIPFLAAPVSGGVVGAENQTLTVMVGGKEET 143
Query: 477 FERSLPLLKVMGAKQFHCG-QIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVL 301
F++ +L V+G FH G QI G KL NN+L+G +E + + + ++ L
Sbjct: 144 FQKVKDILNVIGGNVFHVGEQIDKGTTVKLINNLLIGFYTAGVSEALQIANQKDIDLNDL 203
Query: 300 LDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPI 121
++N S +S +Y T +++ GF +L+ KDLE A +A + +
Sbjct: 204 FSMMNVSYGQS---RIY---ERNYKTFIEPNDFNPGFALKLLRKDLEFAMEVADNNQLDL 257
Query: 120 PLGAVATQLYRIVQSRGYGQKDFSFVFQLLK 28
P+ LYR ++ +GYG +D + +++ LK
Sbjct: 258 PISKSLLDLYRNLEHQGYGDQDMAVLYKYLK 288
>UniRef50_A0UF54 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Burkholderia multivorans ATCC
17616|Rep: 6-phosphogluconate dehydrogenase, NAD-binding
- Burkholderia multivorans ATCC 17616
Length = 289
Score = 117 bits (282), Expect = 2e-25
Identities = 67/213 (31%), Positives = 107/213 (50%)
Frame = -3
Query: 660 AHAKKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKE 481
+HAK+G + ID++T DPN +++ G+GF D PVSGG GA AT+ + GG E
Sbjct: 83 SHAKRGLIVIDTTTADPNSTRKVAAALDAHGIGFIDGPVSGGPKGAATATMTMVLGGADE 142
Query: 480 DFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVL 301
P+L + AKQ H G G+G V KL NN+L G+ + T+E + G++ L
Sbjct: 143 HIAAVQPVLSAISAKQVHVGPAGAGHVTKLLNNLLTGVHLLVTSEAVRAAEAAGVDKARL 202
Query: 300 LDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPI 121
++ L+ S R+ +T PT + +D GF +LM KD+ LA +
Sbjct: 203 IEALSGGSGRNSATLTN------YPTWILNERFDSGFTMKLMRKDMRLALELLQRAHVSA 256
Query: 120 PLGAVATQLYRIVQSRGYGQKDFSFVFQLLKRR 22
P+ + A +L+ +DF+ + + + R
Sbjct: 257 PIASEAGRLWAASAESIGDAEDFNRIVEFVDAR 289
>UniRef50_Q0UVR9 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 288
Score = 117 bits (281), Expect = 3e-25
Identities = 67/174 (38%), Positives = 100/174 (57%), Gaps = 6/174 (3%)
Frame = -3
Query: 660 AHAKKGSLXIDSSTIDPNVPKQIFPIALEKGLG-FTDAPVSGGVMGAQNATLAFMAGGRK 484
A +G L ++ STID K++ E+GLG + DAPVSGGV A+ TL+ + G
Sbjct: 49 ARKDEGRLMLECSTIDVESTKEVGRKLKEEGLGTYIDAPVSGGVPAAEAGTLSMLIGAPP 108
Query: 483 EDFERSLP-LLKVMG--AKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLE 313
D LP L ++G +K F+ +G+G AK++NN L G +ATAE + +G+K GL+
Sbjct: 109 PDPTSLLPSTLSLLGTPSKFFYLHTLGAGLTAKISNNYLSGTILLATAEALAIGVKHGLD 168
Query: 312 PKVLLDVLNNSSARSWSTEVYCPVPGLVPT--APSSRNYDGGFKNELMVKDLEL 157
P L V+ NS+ +SW + P+P + PS+ Y GFK ++M+KDL L
Sbjct: 169 PAALYSVIKNSTGQSWMCDHVLPIPNVQTEYWVPSNSGYKPGFKTQMMLKDLGL 222
>UniRef50_Q606G9 Cluster: Oxidoreductase, Gfo/Idh/MocA family; n=6;
Proteobacteria|Rep: Oxidoreductase, Gfo/Idh/MocA family
- Methylococcus capsulatus
Length = 289
Score = 116 bits (279), Expect = 5e-25
Identities = 68/213 (31%), Positives = 106/213 (49%)
Frame = -3
Query: 651 KKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFE 472
+ G++ +D ST+ ++ + + G F DAPVSGGV GA++ TLA M GGR E E
Sbjct: 83 RPGAVIVDCSTVGVATARRAAEVVRQAGGDFLDAPVSGGVEGARDGTLALMIGGRAETVE 142
Query: 471 RSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDV 292
+ P+L MG++ H G G+GQ K N ++ A E + G + L+ ++DV
Sbjct: 143 KVRPVLAAMGSRLMHMGDTGAGQATKAVNQVMCAGINQAVTEALAFGQALDLDLDKVIDV 202
Query: 291 LNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLG 112
++ +A +W + G S + GFK L KDL + MA + P+PL
Sbjct: 203 VSGGAAGNW----FLDKRGKTMIRGS---FQPGFKLSLHHKDLNICLEMAERLGIPLPLS 255
Query: 111 AVATQLYRIVQSRGYGQKDFSFVFQLLKRRKQK 13
+ Y + +RGYG D S +F+L + K
Sbjct: 256 TRSRDDYAELMARGYGDDDISGLFRLKSAARPK 288
>UniRef50_Q13LQ9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=11;
Proteobacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Burkholderia xenovorans (strain LB400)
Length = 296
Score = 116 bits (278), Expect = 7e-25
Identities = 67/210 (31%), Positives = 105/210 (50%)
Frame = -3
Query: 660 AHAKKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKE 481
A KG++ ID S+ +P + + + L + DAPVSGGV A+ TLA + GG +
Sbjct: 88 ARLAKGAVVIDMSSSEPERSRALGKTLEAQRLAYLDAPVSGGVKRAKEGTLAILVGGHAD 147
Query: 480 DFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVL 301
R PLL MG H G G+G AK NN + + AT E + + + G++P+V+
Sbjct: 148 VLARCKPLLDAMGTNVLHIGTAGAGHAAKALNNYVSAASVAATVEALQIASRFGIDPQVM 207
Query: 300 LDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPI 121
DVLN S+ RS ++E S + GF +LM KDL++A +A + P+
Sbjct: 208 TDVLNASTGRSNTSE------NKAKQFMLSGTFASGFALQLMNKDLKIARALAQAVGHPM 261
Query: 120 PLGAVATQLYRIVQSRGYGQKDFSFVFQLL 31
GA +++ R D + +++LL
Sbjct: 262 TFGATCVEVWDQAAQRSTPATDHTELYRLL 291
>UniRef50_O34948 Cluster: Uncharacterized oxidoreductase ykwC; n=19;
cellular organisms|Rep: Uncharacterized oxidoreductase
ykwC - Bacillus subtilis
Length = 288
Score = 116 bits (278), Expect = 7e-25
Identities = 72/210 (34%), Positives = 110/210 (52%)
Frame = -3
Query: 663 VAHAKKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRK 484
+ +AK+G+ ID +T P++ K+I A EK L DAPVSGG +GAQN TLA M GG K
Sbjct: 83 IENAKEGAYLIDMTTSKPSLAKKIAEAAKEKALFALDAPVSGGDIGAQNGTLAIMVGGEK 142
Query: 483 EDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKV 304
E FE +P+ +MG + G GSGQ K+ N + + + AE M K GLEP+
Sbjct: 143 EAFEACMPIFSLMGENIQYQGPAGSGQHTKMCNQIAIAAGMIGVAEAMAYAQKSGLEPEN 202
Query: 303 LLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSP 124
+L + +A SWS + L P N++ GF + +KD+ +A A +
Sbjct: 203 VLKSITTGAAGSWS------LSNLAPRMLQG-NFEPGFYVKHFIKDMGIALEEAELMGEE 255
Query: 123 IPLGAVATQLYRIVQSRGYGQKDFSFVFQL 34
+P ++A LY + ++G +++L
Sbjct: 256 MPGLSLAKSLYDKLAAQGEENSGTQSIYKL 285
>UniRef50_A2U9T6 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=2; Bacillaceae|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Bacillus coagulans 36D1
Length = 294
Score = 115 bits (277), Expect = 9e-25
Identities = 70/213 (32%), Positives = 109/213 (51%)
Frame = -3
Query: 663 VAHAKKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRK 484
+A KG +D ST+ P+ + EK F DAPVSG V A+ L +AGGRK
Sbjct: 86 LAGLTKGKTVVDMSTVSPSDSIRFAKWVEEKRGHFIDAPVSGSVQPAKEGNLVILAGGRK 145
Query: 483 EDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKV 304
E+ + P+ +V+G H G+ G G AKL+ N+L+G+T +E + G K+GLE K
Sbjct: 146 EEIDAVRPMFEVLGKTIIHFGENGKGSAAKLSINLLLGLTIEGASEAILFGEKLGLEKKD 205
Query: 303 LLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSP 124
L+++++ S+ + P+ + A ++ F ELM KDL LA
Sbjct: 206 LIEMISASACNT-------PIFQMKKKAFLQEDFPAAFMLELMAKDLGLAKEEIKKAGMS 258
Query: 123 IPLGAVATQLYRIVQSRGYGQKDFSFVFQLLKR 25
+PL A + Y ++ G G+ D + V+Q LK+
Sbjct: 259 LPLADAAEKTYSRAKADGTGKADVAAVYQALKQ 291
>UniRef50_A5V0D4 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=4; Chloroflexaceae|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Roseiflexus sp. RS-1
Length = 303
Score = 115 bits (276), Expect = 1e-24
Identities = 73/199 (36%), Positives = 104/199 (52%)
Frame = -3
Query: 654 AKKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDF 475
A+ GSL ID STI P ++I E+ + DAPVSGG GA TL+ M GG F
Sbjct: 88 ARPGSLVIDMSTISPRATQRIAAHLAERHIHMLDAPVSGGSEGAARGTLSIMVGGDVTQF 147
Query: 474 ERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLD 295
ER+LP+ + MG H G IG+GQ KL N +L+ +A +E + G++ + L+
Sbjct: 148 ERALPVFQAMGTTITHLGPIGAGQTTKLVNQILVVGHALAMSEALLFAQAGGVDLRKALE 207
Query: 294 VLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPL 115
++ +A SW P LV R++ GF +L KDL L A + P+P
Sbjct: 208 AVSGGAAGSWMLSNRGP-QILV------RDWRPGFTIDLQQKDLRLVLQEADRLGVPLPG 260
Query: 114 GAVATQLYRIVQSRGYGQK 58
A+ QLYR +Q+RG G +
Sbjct: 261 TALIHQLYRTLQARGLGHE 279
>UniRef50_Q01ZG6 Cluster: 2-hydroxy-3-oxopropionate reductase; n=6;
Bacteria|Rep: 2-hydroxy-3-oxopropionate reductase -
Solibacter usitatus (strain Ellin6076)
Length = 298
Score = 114 bits (274), Expect = 2e-24
Identities = 69/209 (33%), Positives = 108/209 (51%)
Frame = -3
Query: 654 AKKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDF 475
AK G++ +D S+I P V +++ KG+ F DAPVSGG A + TLA M GG+ E F
Sbjct: 85 AKAGTVVVDMSSISPMVSQKVAAACAAKGVEFLDAPVSGGEPKAIDGTLAIMVGGKPEVF 144
Query: 474 ERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLD 295
ER P+L MGA G +G+G V KL N +++ A E + + K GL+P+V+ +
Sbjct: 145 ERVQPVLAKMGASVTLTGAVGAGNVTKLANQIMVACNIAAMGEALVLATKAGLDPEVVFN 204
Query: 294 VLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPL 115
+ A ST + P ++ RN+ GF+ L KDL A A ++ +P
Sbjct: 205 AVKGGLA--GSTVLNAKAPMVI-----GRNFKPGFRINLHEKDLRNALQAAESMKVSLPF 257
Query: 114 GAVATQLYRIVQSRGYGQKDFSFVFQLLK 28
++A Q+ + + G G D S + ++
Sbjct: 258 TSLAQQMLIALMNDGKGNLDHSAIVNFIE 286
>UniRef50_Q0S5S3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Rhodococcus sp. RHA1|Rep: 3-hydroxyisobutyrate
dehydrogenase - Rhodococcus sp. (strain RHA1)
Length = 299
Score = 113 bits (273), Expect = 3e-24
Identities = 70/204 (34%), Positives = 101/204 (49%)
Frame = -3
Query: 648 KGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFER 469
+G + +D STIDP+ +++ A G F DAPVSGGV GA+ TLA M GG + ++
Sbjct: 85 QGLVIVDHSTIDPDTTRRLAQDAQVAGACFLDAPVSGGVQGAEAGTLAVMLGGDEASVKK 144
Query: 468 SLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVL 289
+PL++ FH G GSGQ KL NN + +A E ++ + G++ + VL
Sbjct: 145 VIPLIETYAGNIFHVGPSGSGQAIKLANNQITAANIVALGEGLSSAVAAGVDLDTAVAVL 204
Query: 288 NNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGA 109
SSA S Y P P+ GF + M KDL L A + P P+ +
Sbjct: 205 TKSSANSNVLSNYFPKTLFTEERPT------GFALDFMHKDLGLFLNAAGKAKLPTPVTS 258
Query: 108 VATQLYRIVQSRGYGQKDFSFVFQ 37
+ L+ I Q G G KDF+ V +
Sbjct: 259 LVRDLFSIGQRDGRGGKDFTSVVE 282
>UniRef50_Q9K9L1 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2;
Bacillus|Rep: 3-hydroxyisobutyrate dehydrogenase -
Bacillus halodurans
Length = 299
Score = 113 bits (272), Expect = 4e-24
Identities = 75/215 (34%), Positives = 107/215 (49%), Gaps = 1/215 (0%)
Frame = -3
Query: 663 VAHAKKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRK 484
+A +G + ID ST+D ++ EKG F DAPVSGG MGA+ TL M GG
Sbjct: 83 IAGLSQGKILIDHSTVDRETNVRVAEQIKEKGGAFLDAPVSGGPMGAKAGTLTIMCGGEA 142
Query: 483 EDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKV 304
+ FERS +L G H G IGSG V KL NNM++G+ EC K G++P +
Sbjct: 143 DSFERSKEVLGAYGDYIVHVGPIGSGTVVKLANNMVIGVHQAVLGECYLFVEKAGVDPAI 202
Query: 303 LLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSP 124
+++ S+ S S E V ++ R +D F L+ KD+ LA + LG +
Sbjct: 203 AYEIIKRSAGFSKSME--WSVDAIL-----DRAFDPRFSINLLHKDIGLA--LKLGEQLG 253
Query: 123 IPLGAVATQLYRI-VQSRGYGQKDFSFVFQLLKRR 22
IPL V R+ YG +D S + + L+ +
Sbjct: 254 IPLEMVEKGEERVRAAKEQYGHEDVSAIIRPLEEK 288
>UniRef50_Q1GJB9 Cluster: 6-phosphogluconate dehydrogenase
NAD-binding; n=1; Silicibacter sp. TM1040|Rep:
6-phosphogluconate dehydrogenase NAD-binding -
Silicibacter sp. (strain TM1040)
Length = 304
Score = 113 bits (272), Expect = 4e-24
Identities = 70/204 (34%), Positives = 105/204 (51%)
Frame = -3
Query: 663 VAHAKKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRK 484
+A + +D+ST + + + G GF DAPVSGG GA + L+ M GG
Sbjct: 89 LAQTGAARVIVDTSTSEAATSRTLAAELSALGHGFLDAPVSGGPAGAASGQLSVMLGGET 148
Query: 483 EDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKV 304
+ E + P L+ M AK H G G+G VAKL NNML+ + T E + +G G+ K
Sbjct: 149 QWLEAARPALEAMAAKILHVGPSGAGNVAKLVNNMLVANHMVTTLEALRLGEAAGVAAKE 208
Query: 303 LLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSP 124
+L+V+N+++ RS +EV+ P ++P R++D GF LM KDL LA +A +
Sbjct: 209 MLEVVNSATGRSAISEVHYP-NWVLP-----RSFDSGFSAGLMRKDLRLARALAAEVSVA 262
Query: 123 IPLGAVATQLYRIVQSRGYGQKDF 52
P+ +L+ QS DF
Sbjct: 263 TPMADRVAELWAETQSGLSDSDDF 286
>UniRef50_Q01QM2 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Solibacter usitatus Ellin6076|Rep: 3-hydroxyisobutyrate
dehydrogenase - Solibacter usitatus (strain Ellin6076)
Length = 298
Score = 113 bits (272), Expect = 4e-24
Identities = 72/210 (34%), Positives = 111/210 (52%), Gaps = 2/210 (0%)
Frame = -3
Query: 651 KKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFE 472
+ G++ +D STI ++I K + F DAPV+G GA++ L FM GG + F
Sbjct: 87 RAGAVVVDCSTIAVADSREIGAALKAKSVDFLDAPVTGSTPGAESGNLTFMIGGDEAVFS 146
Query: 471 RSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDV 292
+ PLL MG K + CG G G AKLT N+++ MA E M + K G++PK++L++
Sbjct: 147 KIRPLLDPMGKKIYFCGGAGMGLQAKLTQNLVLSNILMAFNEGMVLATKGGMDPKLMLEI 206
Query: 291 LNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKD--LELASGMALGIRSPIP 118
L+NS+A+S P SRN+ F + M KD L L SG LG+ P+
Sbjct: 207 LDNSAAKSGLISYKAPF-------VFSRNFTTNFSVKWMHKDIGLMLESGKDLGV--PLY 257
Query: 117 LGAVATQLYRIVQSRGYGQKDFSFVFQLLK 28
L + QL++ + G+G +D ++L+
Sbjct: 258 LTGLTRQLFQTAIAAGHGDEDICSTIKVLE 287
>UniRef50_Q9LNP0 Cluster: F1L3.35; n=8; Magnoliophyta|Rep: F1L3.35 -
Arabidopsis thaliana (Mouse-ear cress)
Length = 387
Score = 113 bits (272), Expect = 4e-24
Identities = 66/211 (31%), Positives = 108/211 (51%)
Frame = -3
Query: 645 GSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERS 466
G +D ST+D I + G F +APVSG A++ L F+ G K +E++
Sbjct: 182 GKGYVDVSTVDVASSILISKQIKDTGALFLEAPVSGSKKPAEDGQLIFLTAGDKPLYEKA 241
Query: 465 LPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLN 286
P L +MG +F+ G++G+G KL NM+MG + AE + + K+GL+P VL++V++
Sbjct: 242 APFLDIMGKSKFYLGEVGNGAAMKLVVNMIMGSMMASFAEGILLSQKVGLDPNVLVEVVS 301
Query: 285 NSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAV 106
+ + P+ L + Y F + KD+ LA G+A + P+ A
Sbjct: 302 QGA-------INAPMYSLKGPSMIKSVYPTAFPLKHQQKDMRLALGLAESVSQSTPIAAA 354
Query: 105 ATQLYRIVQSRGYGQKDFSFVFQLLKRRKQK 13
A +LY++ +S G +DFS V + LK K +
Sbjct: 355 ANELYKVAKSYGLSDEDFSAVIEALKAAKSR 385
>UniRef50_A3LTC4 Cluster: 3-hydroxyisobutyrate dehydrogenase-like
protein; n=6; Saccharomycetales|Rep:
3-hydroxyisobutyrate dehydrogenase-like protein - Pichia
stipitis (Yeast)
Length = 355
Score = 113 bits (272), Expect = 4e-24
Identities = 73/220 (33%), Positives = 112/220 (50%), Gaps = 9/220 (4%)
Frame = -3
Query: 633 IDSSTIDPNVPKQIFPIALEK--GLGFTDAPVSGGVMGAQNATLAFMAGG-RKEDFERSL 463
+DSSTID +++ ++ G F D PVSGGV GA+ ATL+FM E L
Sbjct: 130 LDSSTIDIPTSREVHEFVKKELPGADFIDTPVSGGVAGARKATLSFMLSRPNNESISADL 189
Query: 462 -PLLKVMGAKQFHCGQI-GSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVL 289
LL MGA F CG+ G+G AKL+NN L+ +T +A A+ + GL K ++
Sbjct: 190 RTLLNKMGANIFACGETHGAGLAAKLSNNYLLAVTNLAVADSFQLAKSFGLNLKDYAKLV 249
Query: 288 NNSSARSWSTEVYCPVPGLVP---TAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIP 118
+ S+ + W+ CP+PG P P+ Y+GGF ++L KDL LA+ A +
Sbjct: 250 SVSTGKCWAAVDNCPIPGAYPKENNLPADVKYEGGFISKLTRKDLVLATQSAEYANRFLY 309
Query: 117 LGAVATQLY-RIVQSRGYGQKDFSFVFQLLKRRKQKLEXN 1
LG V+ Y + + +D S +++ L ++ + N
Sbjct: 310 LGDVSKHWYDKACEREDLANRDLSVLYEWLGELEKDKDGN 349
>UniRef50_Q4FMJ3 Cluster: 6-phosphogluconate dehydrogenase; n=2;
Candidatus Pelagibacter ubique|Rep: 6-phosphogluconate
dehydrogenase - Pelagibacter ubique
Length = 289
Score = 113 bits (271), Expect = 5e-24
Identities = 60/217 (27%), Positives = 117/217 (53%)
Frame = -3
Query: 663 VAHAKKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRK 484
+++ K+G+ ID S+++P + K+ F I EK + + DAPVSGG +GA+ A+LA M GG +
Sbjct: 81 ISNIKEGATVIDMSSVNPVITKKYFKILKEKNINYLDAPVSGGTIGAEEASLAIMVGGDE 140
Query: 483 EDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKV 304
E F++ LLK++G G + SGQ++KL N +++G+T A AE + + K G P
Sbjct: 141 ETFKQCYDLLKILGNPTL-VGPVTSGQISKLANQIIVGVTIGAVAEAVTLCEKSGTNPNK 199
Query: 303 LLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSP 124
+++ L+ W+ G ++++ K +KD+ +
Sbjct: 200 MIEALSG----GWADSKILQTHG---KRMINKDFTPKGKTTTQLKDMTNIINAGKAAETH 252
Query: 123 IPLGAVATQLYRIVQSRGYGQKDFSFVFQLLKRRKQK 13
+P+ ++ ++Y+ + + G G D S +++ +++ +K
Sbjct: 253 LPISSLVKEMYKDLVADGQGNTDHSSLYKAIEKINKK 289
>UniRef50_Q55W03 Cluster: Putative uncharacterized protein; n=2;
Filobasidiella neoformans|Rep: Putative uncharacterized
protein - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 414
Score = 112 bits (269), Expect = 8e-24
Identities = 69/214 (32%), Positives = 112/214 (52%), Gaps = 9/214 (4%)
Frame = -3
Query: 642 SLXIDSSTIDPNVPKQIFPI---ALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFE 472
++ +D +T+DP V I + + + DAPVSGG + A+ L M G
Sbjct: 170 TMLVDQTTLDPTVSLSISSLIHDSTSRAALMIDAPVSGGTVAAERGELTIMFGSPAPIAT 229
Query: 471 R-SLPLLKVMGAKQ--FHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVL 301
R ++PLL++M + CG G+G K+ NN+++ +A +E + +G + ++ +L
Sbjct: 230 RLAMPLLQMMAREGGVIECGGSGTGVGVKVCNNLVLASNQIALSEGLALGRSLNIDIALL 289
Query: 300 LDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPI 121
V+N SS SWS+ V P+ +P P+SR Y GGF+ LM+KD+ LA A
Sbjct: 290 QSVINTSSGSSWSSRVNPPISS-IPGTPASRGYSGGFQTRLMLKDVNLALQAANKHNLAT 348
Query: 120 PLGAVATQLYRIVQSRGYG---QKDFSFVFQLLK 28
PL + + +Y + S G G KDFS+V +L+
Sbjct: 349 PLTSASKSIYEAICSDGDGDWASKDFSWVKSMLE 382
>UniRef50_Q4Q7T9 Cluster: 2-hydroxy-3-oxopropionate reductase,
putative; n=6; Trypanosomatidae|Rep:
2-hydroxy-3-oxopropionate reductase, putative -
Leishmania major
Length = 299
Score = 111 bits (268), Expect = 1e-23
Identities = 69/209 (33%), Positives = 108/209 (51%), Gaps = 1/209 (0%)
Frame = -3
Query: 648 KGSLXIDSSTIDPNVPKQIFP-IALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFE 472
+G++ +D+STI P+V ++I + EK + DAPVSGG +GA+N TL M GG
Sbjct: 86 EGAIFVDNSTIKPSVAQEIARRLWKEKKVRALDAPVSGGDIGARNGTLTVMVGGDAAALA 145
Query: 471 RSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDV 292
LP+L +G K H G G+GQV K N +++ +A E + K G+ +++
Sbjct: 146 TVLPVLLAVGKKVTHIGDCGAGQVCKAANQIMVAAQMVALGEILVFCEKCGVSGPTVIEA 205
Query: 291 LNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLG 112
+ + SA+ W+ +V P + N GFK L KD+ + A P+P
Sbjct: 206 IKSGSAQCWTLDV-------KPDRLFAGNRAPGFKAALQSKDMGIVMDTAKEFGVPLPST 258
Query: 111 AVATQLYRIVQSRGYGQKDFSFVFQLLKR 25
AV TQL++ + G G +D S V +L+R
Sbjct: 259 AVNTQLFQAMVQNGDGDRDNSAVVSVLER 287
>UniRef50_Q97XZ7 Cluster: Oxidoreductase; n=6; Thermoprotei|Rep:
Oxidoreductase - Sulfolobus solfataricus
Length = 289
Score = 111 bits (268), Expect = 1e-23
Identities = 63/197 (31%), Positives = 103/197 (52%)
Frame = -3
Query: 651 KKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFE 472
K+G + +D ST P K++ E G+ F DAPV+GG GA+ TL M GG+++ F+
Sbjct: 85 KRGLIFVDMSTNSPEFAKKVTKRLSEYGMEFLDAPVTGGDKGAREGTLTIMVGGKEDVFK 144
Query: 471 RSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDV 292
R P+ K MG H G +GSGQ KL N +++ + ++ E + + +G++ L V
Sbjct: 145 RVEPIFKAMGKNIIHVGDVGSGQALKLCNQVVVALNMVSVVEGLLLARSLGIDDDKLFSV 204
Query: 291 LNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLG 112
L+ +A S++ + Y P + + GFK + KDL+ A +A P+
Sbjct: 205 LSTGAANSFTVQYYLP-------KIMKGDLNPGFKAAHLKKDLKYAMEIANSKSLPLLGT 257
Query: 111 AVATQLYRIVQSRGYGQ 61
++A QLY + S G G+
Sbjct: 258 SLALQLYNAMVSLGIGE 274
>UniRef50_P0ABQ3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=25;
Bacteria|Rep: 2-hydroxy-3-oxopropionate reductase -
Escherichia coli O6
Length = 294
Score = 111 bits (268), Expect = 1e-23
Identities = 63/202 (31%), Positives = 103/202 (50%)
Frame = -3
Query: 654 AKKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDF 475
AK G++ ID S+I P ++I KG+ DAPVSGG A + TL+ M GG K F
Sbjct: 84 AKPGTVLIDMSSIAPLASREISEALKAKGIDMLDAPVSGGEPKAIDGTLSVMVGGDKAIF 143
Query: 474 ERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLD 295
++ L+K M H G+IG+G V KL N +++ + A +E + + K G+ P ++
Sbjct: 144 DKYYDLMKAMAGSVVHTGEIGAGNVTKLANQVIVALNIAAMSEALTLATKAGVNPDLVYQ 203
Query: 294 VLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPL 115
+ A S + P+ RN+ GF+ +L +KDL A + G+ + +PL
Sbjct: 204 AIRGGLAGSTVLDAKAPM-------VMDRNFKPGFRIDLHIKDLANALDTSHGVGAQLPL 256
Query: 114 GAVATQLYRIVQSRGYGQKDFS 49
A ++ + +++ G G D S
Sbjct: 257 TAAVMEMMQALRADGLGTADHS 278
>UniRef50_Q0LNZ7 Cluster: 3-hydroxyisobutyrate dehydrogenase
precursor; n=1; Herpetosiphon aurantiacus ATCC
23779|Rep: 3-hydroxyisobutyrate dehydrogenase precursor
- Herpetosiphon aurantiacus ATCC 23779
Length = 301
Score = 110 bits (265), Expect = 3e-23
Identities = 69/203 (33%), Positives = 103/203 (50%)
Frame = -3
Query: 645 GSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERS 466
GS+ ID STI P + I E+ + DAPVSGG A+ LA M GG FER
Sbjct: 91 GSICIDMSTIAPTASRAIAAKLAERQIAMLDAPVSGGPARAKTGELAIMVGGEPSTFERC 150
Query: 465 LPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLN 286
+L+V+G + G GSG V KL NN+ + I MA E + G+ G+E + + +VL
Sbjct: 151 QAVLEVLGGAVSYIGASGSGSVVKLCNNLAISIIAMANIEALAFGVANGVEAETIRNVLL 210
Query: 285 NSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAV 106
N++A ++ E + +P S +Y+ GF EL+ KDL A P+ G +
Sbjct: 211 NATASNYLLERW------LPETVFSGDYNKGFAAELLAKDLNAVLDTARASGVPLWAGGL 264
Query: 105 ATQLYRIVQSRGYGQKDFSFVFQ 37
A Q++ I Q + D++ + Q
Sbjct: 265 AQQMW-IAQKALDPRSDYTALAQ 286
>UniRef50_Q8KL12 Cluster: Probable 6-phosphogluconate dehydrogenase
protein; n=1; Rhizobium etli CFN 42|Rep: Probable
6-phosphogluconate dehydrogenase protein - Rhizobium
etli (strain CFN 42 / ATCC 51251)
Length = 294
Score = 109 bits (263), Expect = 4e-23
Identities = 61/175 (34%), Positives = 96/175 (54%)
Frame = -3
Query: 642 SLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERSL 463
+L ID S+ PN +++ +KGL DAPVSGGV A +L MAGG +D +++
Sbjct: 93 ALVIDMSSSAPNDTRELAERLHQKGLRLVDAPVSGGVKRAVEGSLTIMAGGASDDIDQAD 152
Query: 462 PLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNN 283
P+L MG + F G IGSG K NN + G +A E + +G GL+P+ ++D+LN+
Sbjct: 153 PILCAMGGQIFRTGPIGSGHAMKAINNFVSGAGVLAAIEGVLLGRTFGLDPRTIVDILNS 212
Query: 282 SSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIP 118
SS ++ +TEV + S + GF LM KD+ +A+ ++ + +P
Sbjct: 213 SSGKNNATEV------KMKQFILSETFGSGFALGLMAKDIRIAADLSKALNLQLP 261
>UniRef50_Q930C6 Cluster: Probable; n=8; Alphaproteobacteria|Rep:
Probable - Rhizobium meliloti (Sinorhizobium meliloti)
Length = 295
Score = 109 bits (262), Expect = 6e-23
Identities = 66/211 (31%), Positives = 111/211 (52%)
Frame = -3
Query: 660 AHAKKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKE 481
A A+ G+L ID S+IDPN KQ+ A EKGL + D+P+SGG A L MAGG +
Sbjct: 84 AGAQAGTLIIDMSSIDPNATKQLAADAAEKGLRWVDSPLSGGAPKALIGELTLMAGGTAQ 143
Query: 480 DFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVL 301
D + + +L+ + + H G +G+GQ KL N +L G+ +A AE + + G++ +
Sbjct: 144 DVKDAHAVLRHVASNYTHMGSVGAGQTTKLINQVLCGLGFLAVAEATQLALDAGVDASKI 203
Query: 300 LDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPI 121
L A S + Y +P V +++Y + + MVKDL A +A + +
Sbjct: 204 PQALMGGRADSAILQEY--MPRFV-----TKDYRHTGRIDNMVKDLAGAQDLARRTNTAM 256
Query: 120 PLGAVATQLYRIVQSRGYGQKDFSFVFQLLK 28
PL A +++R++ + G G +D + + + +
Sbjct: 257 PLTAACAEIHRMLTAAGLGGEDQAALMEFFR 287
>UniRef50_Q58PL4 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
uncultured proteobacterium DelRiverFos06H03|Rep:
3-hydroxyisobutyrate dehydrogenase - uncultured
proteobacterium DelRiverFos06H03
Length = 299
Score = 109 bits (261), Expect = 8e-23
Identities = 68/215 (31%), Positives = 111/215 (51%), Gaps = 1/215 (0%)
Frame = -3
Query: 663 VAHAKKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRK 484
+AH K G+ ID+ST + +++ +A KG+ F +APV+ V A L+ GG K
Sbjct: 86 LAHVKAGATVIDTSTSAVELVQELVALAKSKGVDFLEAPVTNAVDMAALGRLSIFVGGDK 145
Query: 483 EDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKV 304
+ FE+ P+ V+G K FH G+ G+G KL N+L ++ A E + +G K G+
Sbjct: 146 DCFEKHKPIFDVIGEKIFHVGEPGNGATIKLLTNLLWFVSAAAIGEGLMLGAKAGIPLHT 205
Query: 303 LLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSP 124
+ + + +S+ SW E VP + + +YD F L KDL L +G+A
Sbjct: 206 VWEAIKSSAGNSWVAE--HDVPSIF-----AGHYDPSFSLALCCKDLGLINGIAKSQGYD 258
Query: 123 IPLGAVATQLYRIVQSRGYGQKDFSF-VFQLLKRR 22
+P+G +A QL++ + YG + V +LL+ R
Sbjct: 259 LPMGGMAQQLFQQAMAT-YGPEAAELHVVKLLEER 292
>UniRef50_A3X9R7 Cluster: 3-hydroxyisobutyrate dehydrogenase family
protein; n=2; Rhodobacterales|Rep: 3-hydroxyisobutyrate
dehydrogenase family protein - Roseobacter sp. MED193
Length = 300
Score = 109 bits (261), Expect = 8e-23
Identities = 66/211 (31%), Positives = 104/211 (49%)
Frame = -3
Query: 657 HAKKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKED 478
+ KKGS+ +D+ST +P+ K++ A G F D PVSGG +GA+ T+ + GG +
Sbjct: 93 YLKKGSIVVDTSTSEPDTTKRLAAAAESNGYTFLDGPVSGGPLGARTGTMTMVVGGDEAG 152
Query: 477 FERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLL 298
F + PLL+ M K H G G+G K+ NN+L + +E M + G+ LL
Sbjct: 153 FTKVRPLLEKMTGKLVHIGPSGAGHTVKIANNLLCAANLVLMSEMAQMAERAGISLTELL 212
Query: 297 DVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIP 118
+N S RS +EV P ++ YD GF LM KD+ LA+G+A + +P
Sbjct: 213 TGINAGSGRSGVSEVN------FPKWITNEAYDSGFTMGLMRKDVGLATGLAERLGIDLP 266
Query: 117 LGAVATQLYRIVQSRGYGQKDFSFVFQLLKR 25
++ + DF+ +++ KR
Sbjct: 267 ATREIAAIWENSREILDDSADFNEIYKYRKR 297
>UniRef50_Q92D17 Cluster: Lin1004 protein; n=10; Bacilli|Rep:
Lin1004 protein - Listeria innocua
Length = 286
Score = 108 bits (259), Expect = 1e-22
Identities = 62/198 (31%), Positives = 104/198 (52%)
Frame = -3
Query: 651 KKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFE 472
K GS+ ID +T P + K+I EKG+G DAPVSGG +GA+N TLA M GG ++ F
Sbjct: 86 KAGSVAIDMTTSSPALAKKIAEAGHEKGIGVLDAPVSGGDIGAKNGTLAIMVGGAEDVFL 145
Query: 471 RSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDV 292
+ P+ +++G+ G GSGQ K+ N + + + E + + GL P +LD
Sbjct: 146 KVKPIFEILGSSVILQGDAGSGQHTKMVNQIAIASNMIGVTEAIIYAERAGLNPSRVLDS 205
Query: 291 LNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLG 112
++ +A SWS + L+P ++ GF + +KD+ +A A + +P
Sbjct: 206 ISGGAAGSWS------LTNLIPRVLQD-DFSPGFFIKHFIKDMGIALSEAKQMGLELPGL 258
Query: 111 AVATQLYRIVQSRGYGQK 58
+A Q+Y+ + +G ++
Sbjct: 259 TLAEQMYQTLAEQGLSEE 276
>UniRef50_Q41DK0 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=2; Bacillaceae|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Exiguobacterium sibiricum
255-15
Length = 293
Score = 108 bits (259), Expect = 1e-22
Identities = 69/214 (32%), Positives = 107/214 (50%)
Frame = -3
Query: 663 VAHAKKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRK 484
+A A G++ ID +T P + +I A + GL DAPV+GG +GA+N TLA + GG +
Sbjct: 83 LASANPGTIVIDMTTSSPALAIRIAEQAAQTGLHALDAPVTGGDLGAKNGTLAILVGGEE 142
Query: 483 EDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKV 304
F+ PL + MG G G GQ AKL N + + + + TAE + K G++P
Sbjct: 143 AAFDTVKPLFEAMGKSIARFGGPGQGQSAKLANQIAIAGSMIGTAEMLLFVTKSGIDPTQ 202
Query: 303 LLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSP 124
+ + + SA SWS E L+P + NY GF + +KD+ LA A +
Sbjct: 203 FVATIKSGSAGSWSLE------NLIPRV-IAENYSPGFFVKHFIKDMRLALERADEMGIS 255
Query: 123 IPLGAVATQLYRIVQSRGYGQKDFSFVFQLLKRR 22
P A+ LY + + G+ + ++ LLK +
Sbjct: 256 TPGLALVKDLYEELAASGHAESGTQALYLLLKEK 289
>UniRef50_A1UP64 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=3; Mycobacterium|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Mycobacterium sp. (strain
KMS)
Length = 305
Score = 108 bits (259), Expect = 1e-22
Identities = 70/209 (33%), Positives = 102/209 (48%)
Frame = -3
Query: 651 KKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFE 472
+ GSL ID STI P+ I EK + F DAPVSGG GA LA M GG ++
Sbjct: 85 RPGSLVIDCSTISPDAAVAIGARLAEKDIAFVDAPVSGGEAGAIAGALAVMMGGDEDAVR 144
Query: 471 RSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDV 292
R+ +L + A H G +G+GQ+ K N ML+ E + + + G++ L V
Sbjct: 145 RAATVLDAVAATSVHVGPVGAGQLVKAANQMLVAGNIALVGEAVTLLQRTGVDVDAALAV 204
Query: 291 LNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLG 112
L A S E P +R++ GF+ +L KDL++A A R +PL
Sbjct: 205 LGGGLAASKVLEAKAP-------KMLARDFAPGFRIDLHYKDLKIALAAAEQARIAVPLT 257
Query: 111 AVATQLYRIVQSRGYGQKDFSFVFQLLKR 25
+ TQL + ++S G G D S + + L+R
Sbjct: 258 GIITQLVQALRSAGDGGLDHSALIKALER 286
>UniRef50_A0LMG6 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=9;
cellular organisms|Rep: 3-hydroxyisobutyrate
dehydrogenase - Syntrophobacter fumaroxidans (strain DSM
10017 / MPOB)
Length = 309
Score = 108 bits (259), Expect = 1e-22
Identities = 63/198 (31%), Positives = 109/198 (55%)
Frame = -3
Query: 654 AKKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDF 475
A+ G + +D +T +P++ ++I A E+G DAPVSGG +GA+NA L+ M GG +E
Sbjct: 97 ARPGIILVDMTTTEPSLAREIHQAAGEQGAFAVDAPVSGGDVGARNAALSIMLGGDREVV 156
Query: 474 ERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLD 295
+ P+L+ MG + G GSGQ AK+ N +++ T + E + G K GL+ +L
Sbjct: 157 DAIRPILEAMGKNLVYLGPAGSGQHAKVCNQIVITGTMIGVCESLMYGFKAGLDLPTMLS 216
Query: 294 VLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPL 115
+ + +A+ W+ + L P R++ GF + +KD+ +A A + +P
Sbjct: 217 SIKDGAAKCWTLD------NLAPRI-LRRDFAPGFFVDHFIKDMGIALQEAARMGLSLPG 269
Query: 114 GAVATQLYRIVQSRGYGQ 61
A+ QLY V+++G+G+
Sbjct: 270 LALTHQLYLAVKAQGHGK 287
>UniRef50_Q656T5 Cluster: Oxidoreductase-like; n=3; Oryza
sativa|Rep: Oxidoreductase-like - Oryza sativa subsp.
japonica (Rice)
Length = 341
Score = 107 bits (258), Expect = 2e-22
Identities = 66/210 (31%), Positives = 103/210 (49%)
Frame = -3
Query: 645 GSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERS 466
G +D ST+D K I G F +APVSG A++ L F+ G + + R
Sbjct: 137 GKGYVDVSTVDAATSKLIGKHITSTGASFLEAPVSGSKKPAEDGLLIFLTAGDESLYNRV 196
Query: 465 LPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLN 286
LL VMG +F G +G G KL NM+MG ++ +E + + K+GL+P L++V++
Sbjct: 197 ASLLDVMGKSRFFLGDVGKGADMKLVVNMVMGSMMVSFSEGLLLSEKVGLDPNTLVEVIS 256
Query: 285 NSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAV 106
+ + P+ L + Y F + KDL LA +A + IP A
Sbjct: 257 QGA-------ISAPMFSLKGPSMVKAAYPTAFPLKHQQKDLRLALALAESVSQSIPTVAA 309
Query: 105 ATQLYRIVQSRGYGQKDFSFVFQLLKRRKQ 16
A +LY++ +S G +DFS V + LK ++Q
Sbjct: 310 ANELYKVAKSLGLADQDFSAVIEALKAKEQ 339
>UniRef50_Q18X68 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=2; Desulfitobacterium hafniense|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Desulfitobacterium hafniense (strain DCB-2)
Length = 298
Score = 107 bits (257), Expect = 2e-22
Identities = 63/199 (31%), Positives = 106/199 (53%)
Frame = -3
Query: 651 KKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFE 472
+ G + +D+STI+ + +I G+ F DAPVSG A+ TL M GG++E FE
Sbjct: 84 RAGQIIVDTSTINYSTTLEIGKQLESVGVEFIDAPVSGMESRAKEGTLTTMCGGKQELFE 143
Query: 471 RSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDV 292
P L+ K + GQ GSGQ+ KL N +L I A AE + M +K+GL+P+ + V
Sbjct: 144 NVKPYLQCFADKILYMGQPGSGQLTKLINQLLFDINVAALAEILPMSVKLGLDPEKVGAV 203
Query: 291 LNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLG 112
+N+ + RS+++E + P+ ++ G+ + KDL + ++ + P+P+
Sbjct: 204 VNSGTGRSYASEFFIPM-------ILKGSFMDGYPMKHAYKDLVSGAEISASLCIPMPVL 256
Query: 111 AVATQLYRIVQSRGYGQKD 55
AT Y++ +G G +D
Sbjct: 257 GAATTTYQMALLKGLGDRD 275
>UniRef50_Q4KH51 Cluster: 3-hydroxyisobutyrate dehydrogenase family
protein; n=16; Gammaproteobacteria|Rep:
3-hydroxyisobutyrate dehydrogenase family protein -
Pseudomonas fluorescens (strain Pf-5 / ATCC BAA-477)
Length = 298
Score = 107 bits (256), Expect = 3e-22
Identities = 63/210 (30%), Positives = 109/210 (51%), Gaps = 1/210 (0%)
Frame = -3
Query: 654 AKKGSLXIDSSTIDPNVPKQIFP-IALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKED 478
A+ G L +D S+++P +++ +A +G+ + DAPVSGG GA+ +LA M GG D
Sbjct: 89 ARAGQLLLDLSSLEPTATREMAAELAASRGVAWVDAPVSGGTPGAEAGSLAIMVGGEATD 148
Query: 477 FERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLL 298
ER P+L +G + H G +G+GQV K N M++ + AE + + + G++ +++
Sbjct: 149 VERVRPVLLTLGQRVTHMGAVGAGQVTKACNQMIVACNALVIAEVVALAERSGVDARLIA 208
Query: 297 DVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIP 118
+ L A S P+ L P SR + ++KDL+ A + S P
Sbjct: 209 EALAGGFADS------KPLQILAPQMAESRFEPVKWHVRTLLKDLDGAVKFSREQGSATP 262
Query: 117 LGAVATQLYRIVQSRGYGQKDFSFVFQLLK 28
+ +A QL R+ +GY +KD + + +L +
Sbjct: 263 ISGLAAQLMRLHGGQGYLEKDPATLVRLYR 292
>UniRef50_Q3DYV4 Cluster: NADP oxidoreductase, coenzyme
F420-dependent:6-phosphogluconate dehydrogenase,
NAD-binding; n=2; Chloroflexus|Rep: NADP oxidoreductase,
coenzyme F420-dependent:6-phosphogluconate
dehydrogenase, NAD-binding - Chloroflexus aurantiacus
J-10-fl
Length = 289
Score = 107 bits (256), Expect = 3e-22
Identities = 68/215 (31%), Positives = 104/215 (48%)
Frame = -3
Query: 651 KKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFE 472
++G L ID + DP + +G+G+ DAPVSGG GA TLA M GG D E
Sbjct: 79 REGQLIIDMGSSDPRHSQTHATTLANRGIGWVDAPVSGGPEGAAAGTLAIMVGGTASDVE 138
Query: 471 RSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDV 292
R+ P+L+ +G + H G G+G K+ N +++G+T A AE M + G++P +L
Sbjct: 139 RAEPILRALG-RPTHVGPPGAGHTVKVINQLIVGLTIQAVAEAMVLAEAYGIDPALLRTA 197
Query: 291 LNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLG 112
L A S +++ ++R Y G K +KDL +A+ MA +P
Sbjct: 198 LAGGFADSKVLQIH-------GQRMAARRYTPGGKVTTQLKDLRMAAAMASAAGIALPHL 250
Query: 111 AVATQLYRIVQSRGYGQKDFSFVFQLLKRRKQKLE 7
Y + RG G+ D S + LL R+ + E
Sbjct: 251 NDTIARYETLVERGLGELDHSALHILLDERRARGE 285
>UniRef50_Q11FC5 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=2; Rhizobiales|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Mesorhizobium sp. (strain
BNC1)
Length = 292
Score = 106 bits (255), Expect = 4e-22
Identities = 69/207 (33%), Positives = 102/207 (49%)
Frame = -3
Query: 645 GSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERS 466
G+L ID STI + + I +G+ DAPVSGGV GA L+ M GG E F ++
Sbjct: 88 GTLVIDMSTISASGIRAIGQDLASRGVDLVDAPVSGGVRGAIAGELSIMCGGSPEAFAKA 147
Query: 465 LPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLN 286
P+L+ MG H G +G GQV K+ N +++G+ A E + G + +L + L
Sbjct: 148 RPVLEGMGTTIIHAGDLGMGQVFKMCNQLMVGVHIQAMCEAFALCRAQGGDLNLLRETLM 207
Query: 285 NSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAV 106
+A SW E L P +++ GF+ +L +KDL LA A P+P A+
Sbjct: 208 GGAAGSWMLE------NLGPQV-IAKDDSAGFRIDLQLKDLRLAGEAAFEKGLPLPGLAM 260
Query: 105 ATQLYRIVQSRGYGQKDFSFVFQLLKR 25
AT LY ++ G G +F+ R
Sbjct: 261 ATSLYLEARAHGEGSNGNQAMFRTYDR 287
>UniRef50_Q0SBQ9 Cluster: 2-hydroxy-3-oxopropionate reductase; n=12;
Actinomycetales|Rep: 2-hydroxy-3-oxopropionate reductase
- Rhodococcus sp. (strain RHA1)
Length = 294
Score = 106 bits (255), Expect = 4e-22
Identities = 71/211 (33%), Positives = 101/211 (47%)
Frame = -3
Query: 657 HAKKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKED 478
H G+L ID S+I P+V + A E+G DAPVSGG GA NA L+ M GG ED
Sbjct: 84 HTPSGALIIDFSSIRPDVTTALAAQATERGFRLIDAPVSGGEAGAVNAALSIMVGGAPED 143
Query: 477 FERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLL 298
FE + P+L V+G H G GSGQ K N +++ AE + G++ +
Sbjct: 144 FESARPILDVVGKTVVHVGPNGSGQTVKAANQLIVAGNIQLLAEAIIFLEAYGVDTAAAV 203
Query: 297 DVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIP 118
+VL A S V R+++ GF+ +L KDL + + A P
Sbjct: 204 EVLGGGLAGS-------AVLNQKAQKMLDRSFEPGFRIDLHHKDLGIVTSAAREAGVVTP 256
Query: 117 LGAVATQLYRIVQSRGYGQKDFSFVFQLLKR 25
LGAV QL ++ G G D S + + ++R
Sbjct: 257 LGAVLAQLMASARANGDGGLDHSGLLRGVER 287
>UniRef50_A0N0V2 Cluster: BtdhL; n=1; Azoarcus anaerobius|Rep: BtdhL
- Azoarcus anaerobius
Length = 303
Score = 106 bits (254), Expect = 5e-22
Identities = 64/201 (31%), Positives = 100/201 (49%)
Frame = -3
Query: 654 AKKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDF 475
A G + ID ST+ P + ++I A KG+ + APVSG A L +A G K+ +
Sbjct: 90 ATPGMVFIDMSTVSPALSERIAAAASAKGIHYLRAPVSGSTTTAAAGALTILASGPKDAY 149
Query: 474 ERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLD 295
ER LPLL+ MG K ++ G + K+ NM++G+T E + +G + G+E +++
Sbjct: 150 ERCLPLLQAMGKKLYYLGPAEQARYLKVAINMMLGVTAGMLGEALALGERGGVEWAQMIE 209
Query: 294 VLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPL 115
V+NNS S P+ ++RN+ F M KD +LA P+PL
Sbjct: 210 VINNSVVGS-------PLLAYKAEMLTTRNFAPMFTASQMAKDFDLALEAGRDANVPMPL 262
Query: 114 GAVATQLYRIVQSRGYGQKDF 52
AV+ Q + + G G+ DF
Sbjct: 263 AAVSRQFLGAMIASGRGELDF 283
>UniRef50_A0LDJ3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Magnetococcus sp. MC-1|Rep: 3-hydroxyisobutyrate
dehydrogenase - Magnetococcus sp. (strain MC-1)
Length = 292
Score = 105 bits (252), Expect = 1e-21
Identities = 65/207 (31%), Positives = 100/207 (48%)
Frame = -3
Query: 645 GSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERS 466
G + I++ST+ +Q + + G F DAPVSG + AQ L F+AGG +R
Sbjct: 88 GKVVINASTVSVEASQQAATLVEQVGGAFLDAPVSGSKIPAQTGKLVFLAGGHHAVIQRC 147
Query: 465 LPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLN 286
PLL MG+ CG +G G KL N+LM A AE + + GLE ++ +D +
Sbjct: 148 EPLLLSMGSAVIPCGAVGDGTRMKLAMNLLMSGMVQALAESLLLVRNSGLEDQLFMDAIK 207
Query: 285 NSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAV 106
NS ++ P+ G+ A +R+++ F L+ KDL L AL +P G
Sbjct: 208 NS-------VLFAPILGMKGQAFLNRDFEPHFPLHLLYKDLNLIHAQALEHHVALPAGDA 260
Query: 105 ATQLYRIVQSRGYGQKDFSFVFQLLKR 25
Q Y +G G D + + Q+L++
Sbjct: 261 IRQGYAQAMQQGLGGLDIAAILQVLEK 287
>UniRef50_Q9HLR4 Cluster: Putative uncharacterized protein Ta0161;
n=2; Thermoplasma|Rep: Putative uncharacterized protein
Ta0161 - Thermoplasma acidophilum
Length = 290
Score = 105 bits (252), Expect = 1e-21
Identities = 65/208 (31%), Positives = 107/208 (51%), Gaps = 1/208 (0%)
Frame = -3
Query: 648 KGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFER 469
+G + ID STI P+ +I EKG DAPV G + + L + GG ++
Sbjct: 90 QGKVFIDMSTISPDTSIEIAKRIKEKGGKMYDAPVIGTSIAVEKKALVVLVGGDLSGYDE 149
Query: 468 SLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVL 289
L+ + + G GSG AKL NN+ +G + AE + G K G+ + DVL
Sbjct: 150 VRDLISATANQVVYMGDNGSGLYAKLVNNLFLGSYMASLAEAVRFGRKNGIPDSTISDVL 209
Query: 288 NN-SSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLG 112
SSARS ++++ VP ++ S +Y F + M+KD+E+ MA R +P+
Sbjct: 210 TKYSSARSPTSDL--KVPKMI-----SEDYSVQFSIKNMLKDMEIVDRMASEKRIALPVA 262
Query: 111 AVATQLYRIVQSRGYGQKDFSFVFQLLK 28
++A QL+R + GYG++D + +++ L+
Sbjct: 263 SLALQLFRYLMDSGYGEEDIAAIYRALR 290
>UniRef50_Q2BFK1 Cluster: Oxidoreductase; n=1; Bacillus sp. NRRL
B-14911|Rep: Oxidoreductase - Bacillus sp. NRRL B-14911
Length = 270
Score = 105 bits (251), Expect = 1e-21
Identities = 67/201 (33%), Positives = 100/201 (49%)
Frame = -3
Query: 645 GSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERS 466
G I+ ++ P + K++ +KG+ D PVSGG GA+N TL MAGG + ER
Sbjct: 73 GQFLIEMTSGSPEMMKKVHAAYQQKGIPVLDGPVSGGTAGAENGTLTVMAGGDADVLERL 132
Query: 465 LPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLN 286
P+L+ M + G +G G+ K N ML GI A AE + + K+ ++ L V+
Sbjct: 133 RPVLESMATNIYLVGSVGDGKAIKAINQMLAGIHMAAAAEAVALAEKLEIDMDKLKAVVG 192
Query: 285 NSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAV 106
+SS SW E + GL+ R++ GFK LM KD+++A G +PL
Sbjct: 193 SSSGNSWMLE--NKMDGLI-----RRDFTPGFKLNLMKKDIQIAVNEGNG--KQLPLANY 243
Query: 105 ATQLYRIVQSRGYGQKDFSFV 43
L++ + G KDFS V
Sbjct: 244 VLDLFK-QSEKDAGDKDFSAV 263
>UniRef50_A3RRS1 Cluster: 2-hydroxy-3-oxopropionate reductase; n=11;
Betaproteobacteria|Rep: 2-hydroxy-3-oxopropionate
reductase - Ralstonia solanacearum UW551
Length = 298
Score = 105 bits (251), Expect = 1e-21
Identities = 76/216 (35%), Positives = 110/216 (50%), Gaps = 3/216 (1%)
Frame = -3
Query: 651 KKGS-LXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDF 475
K GS + ID STI ++I GL F DAPVSGG MGAQ ATL+ M GG+ E
Sbjct: 89 KPGSAVCIDHSTISAVATRRIAAELETAGLDFLDAPVSGGTMGAQKATLSIMVGGKAEVL 148
Query: 474 ERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLD 295
ER PLL+++G H G G+GQVAK N ++ I AE M G +P +L
Sbjct: 149 ERVRPLLQLLGTTITHIGDHGAGQVAKACNQIVQVINIQGIAEAMLFARAQGTDPSRVLA 208
Query: 294 VLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMA--LGIRSPI 121
+ A S ++ P + R++ G + L KD L +A LG++ P
Sbjct: 209 AIGPGFAGSRMLDMMGP-------KMAERDFAAGIEARLHDKDFGLVRDIARELGLKMP- 260
Query: 120 PLGAVATQLYRIVQSRGYGQKDFSFVFQLLKRRKQK 13
+ VA+QL +V S G+G+ D S + ++L+ + +
Sbjct: 261 AMELVASQLDALVAS-GWGRDDTSSLLRVLEAQNDR 295
>UniRef50_A5GPC0 Cluster: Hydroxyacid dehydrogenase/reductase family
protein; n=14; Cyanobacteria|Rep: Hydroxyacid
dehydrogenase/reductase family protein - Synechococcus
sp. (strain WH7803)
Length = 302
Score = 104 bits (249), Expect = 2e-21
Identities = 65/208 (31%), Positives = 106/208 (50%)
Frame = -3
Query: 648 KGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFER 469
+GSL ID STI P+ +++ +G+ + DAPV+GG GA+ TL + GG D +R
Sbjct: 101 EGSLVIDCSTISPSTSQRMARRLAHRGVRYLDAPVTGGTEGAKAGTLTVLCGGSDADLDR 160
Query: 468 SLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVL 289
++P+L+ +G H G +GSGQ K N +L+ + A AE + +G + L + +++ L
Sbjct: 161 AMPVLETIGGSIHHFGAVGSGQQVKAVNQVLVAGSYAAVAEAIALGQHLQLPMQQVVNAL 220
Query: 288 NNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGA 109
+ +A SW+ E +A S +Y GFK L KDL +A A +P+
Sbjct: 221 RHGAAGSWALEHR-------SSAMLSDHYPLGFKLALHHKDLGIALQAAAEAGLDLPITQ 273
Query: 108 VATQLYRIVQSRGYGQKDFSFVFQLLKR 25
+ + + G G D S + + L R
Sbjct: 274 AVQAQEQTLMNAGLGDADVSALRRHLPR 301
>UniRef50_Q13PY3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2;
Burkholderiales|Rep: 3-hydroxyisobutyrate dehydrogenase
- Burkholderia xenovorans (strain LB400)
Length = 302
Score = 103 bits (248), Expect = 3e-21
Identities = 66/210 (31%), Positives = 104/210 (49%), Gaps = 1/210 (0%)
Frame = -3
Query: 663 VAHAKKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRK 484
V+ + +D ST P+V I ++ + F APVSGG + A+ TL MA G
Sbjct: 80 VSQGSSVRIVVDLSTTGPSVSNVIARKLADRHIQFLGAPVSGGTVAAEKGTLTVMAAGPM 139
Query: 483 EDFERSLPLLKVMGAKQFHCGQ-IGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPK 307
E FE P L+V+G F+ G G GQ K+ NN L + +A+ E + G+K GL+
Sbjct: 140 EAFETVEPWLRVIGKNIFYLGSGAGLGQTMKIINNTLCAVGMVASCEALVFGVKAGLDSA 199
Query: 306 VLLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRS 127
++LD+LN SS RS++T +P R++ F EL+ KD++L A +
Sbjct: 200 MMLDILNVSSGRSFAT------LEKIPQCILHRDFPMRFTTELIHKDVKLCIEEAEKLGV 253
Query: 126 PIPLGAVATQLYRIVQSRGYGQKDFSFVFQ 37
P+ + A ++G G KD++ +
Sbjct: 254 PMIVSPAARAFLSFAITQGDGGKDYAHTIE 283
>UniRef50_Q89UN2 Cluster: Bll1384 protein; n=9; Bacteria|Rep:
Bll1384 protein - Bradyrhizobium japonicum
Length = 356
Score = 103 bits (247), Expect = 4e-21
Identities = 65/204 (31%), Positives = 102/204 (50%)
Frame = -3
Query: 633 IDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLL 454
ID ST+ + +I + ++ + D PVSGGV GA+ TLA M G K +FE P L
Sbjct: 144 IDLSTVGSTMASKIHGLLAKRDIVQIDCPVSGGVGGAEKGTLAVMVSGPKAEFELLKPAL 203
Query: 453 KVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSA 274
V+G F + G+ Q KL NN L +AT+E + MG+K GL+P V++DV+N S
Sbjct: 204 DVIGKVFFIGEKPGAAQTMKLANNFLSATAIVATSEAVVMGVKAGLDPAVMIDVINAGSG 263
Query: 273 RSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVATQL 94
+ ++ P + R +D GF LMVKD+ LA + + + +L
Sbjct: 264 MNTASR------DKFPRSVLPRTFDFGFATGLMVKDVRLALEEMKQLGLSMEVADAVGRL 317
Query: 93 YRIVQSRGYGQKDFSFVFQLLKRR 22
+ V S DF+ + ++++
Sbjct: 318 WETVISAEGADSDFTAAIKPIEKK 341
>UniRef50_Q89HA0 Cluster: Oxidoreductase; n=1; Bradyrhizobium
japonicum|Rep: Oxidoreductase - Bradyrhizobium japonicum
Length = 313
Score = 103 bits (246), Expect = 5e-21
Identities = 64/205 (31%), Positives = 102/205 (49%), Gaps = 1/205 (0%)
Frame = -3
Query: 645 GSLXIDSSTIDPNVPKQIFP-IALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFER 469
G L +D S+I P+ + + + G G+ DAPVSGG GA+ TLA MAGG D ER
Sbjct: 110 GKLVVDFSSIHPDAARDLATRLKAANGAGWIDAPVSGGTKGAEEGTLAIMAGGDASDIER 169
Query: 468 SLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVL 289
P + M + H G G+GQ AKL N +++G AE + + G++ L + L
Sbjct: 170 VRPYVLTMARRFTHMGPTGAGQTAKLCNQVIVGCAMAVLAEATRLAVNAGIDANRLPEAL 229
Query: 288 NNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGA 109
A S +++ VP +V S G M+KDL+ + +A +P+P+
Sbjct: 230 AGGFADSIPLQLF--VPRMVQGIHSPPL--GHIAT--MLKDLDTVADVAQTTSTPVPMAT 283
Query: 108 VATQLYRIVQSRGYGQKDFSFVFQL 34
+A QL+R+ ++ D +++L
Sbjct: 284 LAGQLFRLAKAARGADADALEIYKL 308
>UniRef50_Q1N6I0 Cluster: Putative oxidoreductase protein; n=1;
Oceanobacter sp. RED65|Rep: Putative oxidoreductase
protein - Oceanobacter sp. RED65
Length = 289
Score = 102 bits (244), Expect = 9e-21
Identities = 70/216 (32%), Positives = 109/216 (50%)
Frame = -3
Query: 660 AHAKKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKE 481
++ K G+L ID +T + ++ LEK + + DAPVSGG GA + L M GG+
Sbjct: 84 SNLKPGTLVIDHTTTSAELACEMQAKLLEKQVDYVDAPVSGGEQGAISGQLTIMCGGQAL 143
Query: 480 DFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVL 301
ER+ + + H G IGSGQ+ K+ N + + A AE ++ G + GL+ + +
Sbjct: 144 AAERAQGITQAYSKSFTHMGPIGSGQLTKMVNQICVAGLIEALAEGIHFGQQAGLDMEKV 203
Query: 300 LDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPI 121
+ V+ + +A SW + T + YD GF + M KDLE+ A + + +
Sbjct: 204 MKVVGSGAASSWQLQ------NRYQTMLEDQ-YDFGFAVDHMRKDLEICLKEAKKMNTSL 256
Query: 120 PLGAVATQLYRIVQSRGYGQKDFSFVFQLLKRRKQK 13
P A+ QLY +Q G+GQ D S LLKR + K
Sbjct: 257 PSTAMVDQLYGELQQSGHGQLDTS---SLLKRLQNK 289
>UniRef50_A2SP40 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Methylibium petroleiphilum PM1|Rep: 3-hydroxyisobutyrate
dehydrogenase - Methylibium petroleiphilum (strain PM1)
Length = 297
Score = 102 bits (244), Expect = 9e-21
Identities = 69/208 (33%), Positives = 103/208 (49%), Gaps = 1/208 (0%)
Frame = -3
Query: 663 VAHAKKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRK 484
VA A+ GS I++STIDPN +++ A + G+ D +SG A L F GG
Sbjct: 82 VAQARPGSTLIETSTIDPNTIREVAQAATKSGIRILDIALSGEPPQAVLGELVFQVGGPD 141
Query: 483 EDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNML-MGITGMATAECMNMGIKMGLEPK 307
E ++ L LL+V+ K G IG+ + KL NN++ +G +A AE +G+K G+EPK
Sbjct: 142 ELIDQHLELLQVLAKKINRTGGIGTAKTVKLVNNLMSLGNVAVA-AEAFVLGVKCGMEPK 200
Query: 306 VLLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRS 127
L ++L+ S RS + G +Y FK L +KD+ L +A
Sbjct: 201 RLYEILSVSGGRSAHF-----ISGFQKVIEG--DYGASFKTSLALKDINLILDLANEEHY 253
Query: 126 PIPLGAVATQLYRIVQSRGYGQKDFSFV 43
L V LYR RG G+++F+ V
Sbjct: 254 AARLAPVIASLYRDAVGRGLGEENFTSV 281
>UniRef50_Q2JEV5 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=6; Bacteria|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Frankia sp. (strain CcI3)
Length = 302
Score = 101 bits (243), Expect = 1e-20
Identities = 65/209 (31%), Positives = 99/209 (47%)
Frame = -3
Query: 651 KKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFE 472
+ G++ +D +T + ++I E G+GF DAPVSGG GA L+ M GG E E
Sbjct: 86 RPGAIIVDHTTTSAELAEEIAARTAEVGVGFVDAPVSGGEAGAMAGRLSIMCGGDPETIE 145
Query: 471 RSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDV 292
R+ P+L GA G +GSGQ+ K+ N +L+ AE +N I GL+ ++L
Sbjct: 146 RARPVLAAYGATITRIGPVGSGQLTKMVNQILVAGAVEGAAEAINFAIAAGLDTDLVLSA 205
Query: 291 LNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLG 112
+ +A SW Y G +D GF + M KDL + A P+P+
Sbjct: 206 VAGGAANSW----YLANRGQTMVRD---EFDFGFAVDWMRKDLRICLAEAGRRGIPLPMI 258
Query: 111 AVATQLYRIVQSRGYGQKDFSFVFQLLKR 25
+A + Q+ G G D + V + +R
Sbjct: 259 ELAERDLAAAQADGEGGLDTTVVIRQRRR 287
>UniRef50_Q03UI4 Cluster: 3-hydroxyisobutyrate dehydrogenase related
enzyme; n=2; Lactobacillales|Rep: 3-hydroxyisobutyrate
dehydrogenase related enzyme - Leuconostoc mesenteroides
subsp. mesenteroides (strain ATCC 8293 /NCDO 523)
Length = 287
Score = 101 bits (243), Expect = 1e-20
Identities = 64/198 (32%), Positives = 101/198 (51%), Gaps = 1/198 (0%)
Frame = -3
Query: 660 AHAKKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKE 481
A AK+GS+ +D +T P + +Q+ + G DAPVSGG +GA+N TLA M GG ++
Sbjct: 82 AGAKEGSILVDMTTSTPRLAEQLAQTGADLGFKVLDAPVSGGDIGAKNGTLAIMVGGEQQ 141
Query: 480 DFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVL 301
+ P+L V+G + G G GQ K++NN+ + T + AE + GL+ +
Sbjct: 142 VLDEIKPVLSVIGQQIVFAGSAGKGQHMKMSNNIGVAATVITMAESLVYAKAAGLDLESA 201
Query: 300 LDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPI 121
+V +A SWS + Y P +Y GF + ++KDL +A A + +
Sbjct: 202 YNVWRKGAAGSWSVDNYIP-------RIFQGDYAPGFYVKHLLKDLRIALDAAKEMDIDL 254
Query: 120 PLGAVATQLY-RIVQSRG 70
P +A QL+ R+ Q G
Sbjct: 255 PNTKLAEQLFERLSQEHG 272
>UniRef50_A6SW62 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Janthinobacterium sp. Marseille|Rep:
3-hydroxyisobutyrate dehydrogenase - Janthinobacterium
sp. (strain Marseille) (Minibacterium massiliensis)
Length = 298
Score = 101 bits (243), Expect = 1e-20
Identities = 62/199 (31%), Positives = 96/199 (48%)
Frame = -3
Query: 645 GSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERS 466
GS+ ID T P V + I G+G+ DAPV GGV+ A++A+L M G ER
Sbjct: 91 GSIAIDMGTSAPAVTRSISAELATLGIGYLDAPVMGGVVFAKDASLDIMVSGDDASIERC 150
Query: 465 LPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLN 286
PL MG K + CG IGS V K N + + T E M +G K GL+ KV+ + ++
Sbjct: 151 RPLFDAMGRKLWPCGDIGSAHVLKAMTNYINACALINTLEAMTIGRKFGLDSKVMAEAID 210
Query: 285 NSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAV 106
V +P ++ + + G +L+ KD+++A A + + +PLG
Sbjct: 211 VMCNGRQHPVVKKIIPHVL-----THKFGTGMAMQLIAKDVKIAVDSAHSVGAAVPLGEA 265
Query: 105 ATQLYRIVQSRGYGQKDFS 49
+L+R + G +D S
Sbjct: 266 TEKLWRAACEQIGGSRDHS 284
>UniRef50_A0FZ96 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Burkholderia phymatum STM815|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Burkholderia phymatum STM815
Length = 305
Score = 101 bits (243), Expect = 1e-20
Identities = 60/188 (31%), Positives = 103/188 (54%), Gaps = 1/188 (0%)
Frame = -3
Query: 645 GSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERS 466
G + ID ++ P + + G+ DAPVSG + A T++ +A G K+ FE++
Sbjct: 86 GKIVIDQTSGVPAETRDFARQLADIGVALFDAPVSGAMATAIAGTISIIASGPKDAFEKT 145
Query: 465 LPLLKVMGAKQFHCGQ-IGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVL 289
LP+L+ + FHCG+ +G+GQ K NNM+ +AT E + MG K GL +++ + +
Sbjct: 146 LPVLQSISPNVFHCGERVGNGQTMKTVNNMMNVSCRLATLEVVAMGRKFGLPLELMTEAI 205
Query: 288 NNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGA 109
N ++AR+++++ G++P R F L VKD+ A +A + P+P+GA
Sbjct: 206 NATTARNYTSQ------GMLPAIAEGRQ-STKFWLALQVKDIHQAITLAAEQKVPMPIGA 258
Query: 108 VATQLYRI 85
VA + +I
Sbjct: 259 VARSILQI 266
>UniRef50_Q84VC8 Cluster: Gamma hydroxybutyrate dehydrogenase-like
protein; n=3; Magnoliophyta|Rep: Gamma hydroxybutyrate
dehydrogenase-like protein - Oryza sativa subsp.
japonica (Rice)
Length = 293
Score = 101 bits (241), Expect = 2e-20
Identities = 66/209 (31%), Positives = 108/209 (51%), Gaps = 2/209 (0%)
Frame = -3
Query: 648 KGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFER 469
+G +D ST+D +I +KG F +APVSG A++ L +A G K ++
Sbjct: 86 EGKGYVDMSTVDAATSCKISEAIKQKGGAFVEAPVSGSKKPAEDGQLVILAAGDKVLYDD 145
Query: 468 SLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVL 289
+P V+G K F G+IG+G KL NM+MG A +E +++ GL P+ LLDVL
Sbjct: 146 MVPAFDVLGKKSFFLGEIGNGAKMKLVVNMIMGSMMNALSEGLSLADNSGLSPQTLLDVL 205
Query: 288 NNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPI--PL 115
+ + + P+ L + +Y+ F + KD+ LA +ALG + + P+
Sbjct: 206 DLGAIAN-------PMFKLKGPSMLQGSYNPAFPLKHQQKDMRLA--LALGDENAVSMPV 256
Query: 114 GAVATQLYRIVQSRGYGQKDFSFVFQLLK 28
A + + ++ +S G G DFS V+++LK
Sbjct: 257 AAASNEAFKKARSLGLGDLDFSAVYEVLK 285
>UniRef50_Q97ZE5 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=4;
Sulfolobaceae|Rep: 3-hydroxyisobutyrate dehydrogenase -
Sulfolobus solfataricus
Length = 289
Score = 101 bits (241), Expect = 2e-20
Identities = 66/213 (30%), Positives = 106/213 (49%), Gaps = 1/213 (0%)
Frame = -3
Query: 648 KGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFER 469
KG + ID STI P + + G DAPV G + + L + GG K+ F+
Sbjct: 83 KGKILIDMSTISPTLSISLAKRIESNGGTMFDAPVIGTSVFVEQKKLVVLVGGPKDKFDI 142
Query: 468 SLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVL 289
+ K + + G G G +KL NN+L+ A AE N GI+ GLEP+ ++++L
Sbjct: 143 VNDIAKETASLVVYMGPNGMGLYSKLVNNLLLASYVAAIAEAYNFGIRAGLEPQQVVNIL 202
Query: 288 NN-SSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLG 112
SSARS +TE+ P L+ +Y F + M KDLE+ A ++ P+
Sbjct: 203 TTLSSARSPTTEL--KAPKLL-----KEDYSTQFATKHMRKDLEIIMREAQNLKIITPVS 255
Query: 111 AVATQLYRIVQSRGYGQKDFSFVFQLLKRRKQK 13
++ +LY++ ++ GY + DF V ++ K+ K
Sbjct: 256 SLVLELYKMAEALGYSEADFISVVEVFKKLSPK 288
>UniRef50_Q830A7 Cluster: 2-hydroxy-3-oxopropionate reductase; n=7;
Firmicutes|Rep: 2-hydroxy-3-oxopropionate reductase -
Enterococcus faecalis (Streptococcus faecalis)
Length = 296
Score = 100 bits (240), Expect = 3e-20
Identities = 60/193 (31%), Positives = 93/193 (48%)
Frame = -3
Query: 645 GSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERS 466
G + +D +T P + ++I A E G DAPVSGG +GA+N TL M GG +E ++
Sbjct: 88 GKIVVDLTTSTPTLAEKIAKKAAEVGAHALDAPVSGGDLGAKNGTLTIMVGGDQESYDTV 147
Query: 465 LPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLN 286
LP+ K G G G GQ K+ N +++ T E + GL + +L+ +
Sbjct: 148 LPIFKTFGKTFMLHGSAGKGQHTKMANQLMIAGTMTGLTEMLVYANATGLTLEKVLETVG 207
Query: 285 NSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAV 106
SA +WS Y P +Y GF + +KDL++A A + P+P
Sbjct: 208 GGSAANWSLSNYGP-------RILKEDYTPGFFVKHFIKDLKIALDEAKKLDLPLPATQK 260
Query: 105 ATQLYRIVQSRGY 67
AT+LY + +G+
Sbjct: 261 ATELYESLADKGF 273
>UniRef50_Q47AR2 Cluster: NADP oxidoreductase, coenzyme
F420-dependent:6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Dechloromonas aromatica RCB|Rep: NADP
oxidoreductase, coenzyme
F420-dependent:6-phosphogluconate dehydrogenase,
NAD-binding - Dechloromonas aromatica (strain RCB)
Length = 287
Score = 100 bits (240), Expect = 3e-20
Identities = 65/209 (31%), Positives = 100/209 (47%)
Frame = -3
Query: 651 KKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFE 472
+ G + +D STI P ++I G+ F DAPVSGG +GA +L+ MAGG F
Sbjct: 82 ESGLVAVDMSTIAPAAARRIGEDLAAAGIDFIDAPVSGGEVGAIAGSLSIMAGGSDAAFA 141
Query: 471 RSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDV 292
++ P + MG H G G+GQVAK N ++ G+ +A AE K G++ + +
Sbjct: 142 KAKPAFECMGKNIVHVGASGAGQVAKAANQIVTGMGVLAVAEAFAFAAKNGVDSAKVREA 201
Query: 291 LNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLG 112
L A S E + RN+ GFK+ + KDL + A + +P
Sbjct: 202 LLGGFAYSKILENH-------GQRMLDRNFKPGFKSWMHEKDLNIVMQTAHELGLCLPGS 254
Query: 111 AVATQLYRIVQSRGYGQKDFSFVFQLLKR 25
A Q++ + G G++D V +LL+R
Sbjct: 255 AATAQMFNAMVGSGLGEEDSIAVLKLLER 283
>UniRef50_A1B741 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3;
Bacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Paracoccus denitrificans (strain Pd 1222)
Length = 309
Score = 100 bits (240), Expect = 3e-20
Identities = 69/209 (33%), Positives = 101/209 (48%), Gaps = 1/209 (0%)
Frame = -3
Query: 645 GSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERS 466
G++ +D ST +V +QI KG+ F DAPVSGG GA + LA GG +E ++R
Sbjct: 87 GTVWLDLSTNSVDVVRQIHAELAPKGIHFIDAPVSGGPAGAASGQLAIWCGGEREVYDRC 146
Query: 465 LPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLN 286
LP L+ M + + G IG+G +AKL NNM AE ++MG+K GLEP L + +
Sbjct: 147 LPWLEKMADQPRYIGDIGAGTIAKLVNNMASTAIISVLAEALSMGVKAGLEPGPLWEAIR 206
Query: 285 NSSARSWSTEVYCPVPGLVPTAPSSRNYD-GGFKNELMVKDLELASGMALGIRSPIPLGA 109
+A +Y + A YD F L+ KD LA + P+ L
Sbjct: 207 TGAA--GRMRMYDNIGRRFMQA----KYDPPSFALRLIHKDASLALQVGRDFGVPMRLCT 260
Query: 108 VATQLYRIVQSRGYGQKDFSFVFQLLKRR 22
+ R +RG+G++D L + R
Sbjct: 261 LVESDIREALNRGWGERDSQSYLALQQER 289
>UniRef50_Q5WBB8 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Bacillus clausii KSM-K16|Rep: 3-hydroxyisobutyrate
dehydrogenase - Bacillus clausii (strain KSM-K16)
Length = 283
Score = 100 bits (239), Expect = 4e-20
Identities = 69/210 (32%), Positives = 101/210 (48%), Gaps = 2/210 (0%)
Frame = -3
Query: 663 VAHAKKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRK 484
+ H + G +D ST D + A KG+ + D PVSGG GA TL M GG K
Sbjct: 82 LCHLQTGGFLLDLSTTDVQTTLAMEKAAAAKGIYYLDCPVSGGPAGADAGTLTIMVGGDK 141
Query: 483 EDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLM-GITGMATAECMNMGIKMGLEPK 307
+ + PLL ++G + G G+GQ KL NNML+ GIT + +E M + G+ +
Sbjct: 142 QAYFSVKPLLDILGDTILYVGDSGAGQTVKLCNNMLVAGITTL-LSETMAVASDHGVSRR 200
Query: 306 VLLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGG-FKNELMVKDLELASGMALGIR 130
+L ++ SS + +V+ L+ S +YD F + M KDLEL ++ R
Sbjct: 201 LLAQIIQQSSGHNRVLDVF--GENLI-----SGSYDNVLFYLKHMAKDLELYMALSQDSR 253
Query: 129 SPIPLGAVATQLYRIVQSRGYGQKDFSFVF 40
P QLYR +G G KD + V+
Sbjct: 254 KPQHAAGTVNQLYRSALHQGKGDKDATAVY 283
>UniRef50_Q6UCZ9 Cluster: Predicted oxidoreductase; n=2;
environmental samples|Rep: Predicted oxidoreductase -
uncultured marine proteobacterium ANT32C12
Length = 309
Score = 100 bits (239), Expect = 4e-20
Identities = 61/206 (29%), Positives = 103/206 (50%)
Frame = -3
Query: 645 GSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERS 466
G++ ID +T + K++ +AL+K + F DAP+SGG GA++ L+ M GG K +E
Sbjct: 108 GTIIIDHTTTSATLSKEMNELALQKDVIFLDAPISGGQAGAESGQLSVMVGGDKASYESV 167
Query: 465 LPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLN 286
P+L + G GSGQ+ K+ N + + A AE +N K+GL +++V+
Sbjct: 168 KPILDNYSKFTKYMGPSGSGQLTKMVNQICIAGLVQALAEGVNFSEKVGLNTSDVMEVIT 227
Query: 285 NSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAV 106
+A+SW E YD GF + M KDL++ S A + + I + +
Sbjct: 228 KGAAQSWQMENRW-------ETMLKDEYDHGFAVDWMRKDLDIVSEQAGQVGANIEITEM 280
Query: 105 ATQLYRIVQSRGYGQKDFSFVFQLLK 28
+ Y+ +Q G+ D S + + +K
Sbjct: 281 VNKFYKDIQDLDGGRWDTSSLLKRIK 306
>UniRef50_Q12CU4 Cluster: 2-hydroxy-3-oxopropionate reductase; n=17;
Proteobacteria|Rep: 2-hydroxy-3-oxopropionate reductase
- Polaromonas sp. (strain JS666 / ATCC BAA-500)
Length = 298
Score = 100 bits (239), Expect = 4e-20
Identities = 71/213 (33%), Positives = 100/213 (46%)
Frame = -3
Query: 660 AHAKKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKE 481
A K GSL +D ++I P + G+ D PVSGG +GA+ TL MAGG+
Sbjct: 90 AAMKPGSLFLDMASITPREARDHAARLGALGIAHLDTPVSGGTVGAEQGTLVIMAGGKPA 149
Query: 480 DFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVL 301
DFERSLPLLKV G + H G GSGQ+ KL N M++GIT A AE + K G + +
Sbjct: 150 DFERSLPLLKVFG-RATHVGPHGSGQLTKLANQMIVGITIGAVAEALLFATKGGADMAKV 208
Query: 300 LDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPI 121
+ + A S +++ R++ + + +KD+ A A I
Sbjct: 209 KEAITGGFADSRVLQLH-------GQRMVERDFAPRARLSIQLKDMRNALATAQEIGFDA 261
Query: 120 PLGAVATQLYRIVQSRGYGQKDFSFVFQLLKRR 22
P+ + QLY G D S +F L R
Sbjct: 262 PITGLFEQLYAEGVEHGLTDLDQSGLFVELASR 294
>UniRef50_Q89R44 Cluster: Oxidoreductase; n=23; Bacteria|Rep:
Oxidoreductase - Bradyrhizobium japonicum
Length = 305
Score = 99 bits (238), Expect = 5e-20
Identities = 61/206 (29%), Positives = 98/206 (47%), Gaps = 1/206 (0%)
Frame = -3
Query: 648 KGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFER 469
K S+ + S+T+DP+V +++ G + DAP+SGG A L +A G F +
Sbjct: 94 KDSVFLSSATMDPDVARRLAKQLEATGRHYLDAPISGGAQRAAQGELTILASGSPAAFAK 153
Query: 468 SLPLLKVMGAKQFHCGQ-IGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDV 292
+ P L M AK + G G G K+ N +L G+ A +E M K GL+ + + +V
Sbjct: 154 ARPALDAMAAKLYELGDAAGQGAAFKMINQLLAGVHIAAASEAMAFAAKQGLDIRKVYEV 213
Query: 291 LNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLG 112
+ S+ SW E P +Y E+ VKDL + MA R P+P+
Sbjct: 214 ITASAGNSWMFENRMP-------HVLDGDYTPRSAVEIFVKDLGIIQDMARSARFPVPVS 266
Query: 111 AVATQLYRIVQSRGYGQKDFSFVFQL 34
A A Q++ + + G G+ D + V ++
Sbjct: 267 AAALQMFLMTAAAGMGRDDDASVARM 292
>UniRef50_Q183P5 Cluster: 2-hydroxy-3-oxopropionate reductase; n=5;
Bacteria|Rep: 2-hydroxy-3-oxopropionate reductase -
Clostridium difficile (strain 630)
Length = 296
Score = 99 bits (238), Expect = 5e-20
Identities = 59/209 (28%), Positives = 109/209 (52%)
Frame = -3
Query: 651 KKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFE 472
K+GS+ +D S++ P + GL F D+PVSGG A + TLAFMAGG++E ++
Sbjct: 84 KEGSIVVDMSSVTPTESILCANKLKDMGLEFIDSPVSGGEPKAIDGTLAFMAGGKEEIYK 143
Query: 471 RSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDV 292
+ P +MG+ G GSG V KLTN +++ +T A +E + K G +P+ +
Sbjct: 144 KVEPFFNIMGSSSILIGDNGSGSVTKLTNQVIVNLTIAAVSEAFVLAAKAGADPEKVYKA 203
Query: 291 LNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLG 112
+ A ST + +P ++ +R++ G K + +KD++ A + P+P+
Sbjct: 204 IRGGLA--GSTILDAKIPMIM-----NRDFKPGGKISINLKDIKNVMQTAHNLDVPLPMT 256
Query: 111 AVATQLYRIVQSRGYGQKDFSFVFQLLKR 25
+ ++ + ++ G+ + D S + Q ++
Sbjct: 257 SQLLEIMQTLKVHGHLEDDHSGIAQYFEK 285
>UniRef50_A0G5F9 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=2; Burkholderia|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Burkholderia phymatum
STM815
Length = 307
Score = 99 bits (238), Expect = 5e-20
Identities = 68/204 (33%), Positives = 104/204 (50%), Gaps = 1/204 (0%)
Frame = -3
Query: 633 IDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLL 454
+D ST+ V K++ L KG+ DAPVSGG GA+ TLA MA G E L
Sbjct: 102 VDLSTVGSRVEKEVAQGLLAKGVETVDAPVSGGAAGAKKGTLAIMAAGSPVALEEVRGLF 161
Query: 453 KVMGAKQFHCG-QIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSS 277
V+G K F G + G GQ+ KL NNML T+E G++ GL+P+V++ V+N S
Sbjct: 162 DVLG-KAFVVGDKAGQGQLLKLLNNMLSSTAFAITSEAFVAGVRGGLDPEVMMSVINAGS 220
Query: 276 ARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVATQ 97
++ +T P L P S +D GF + KD+ LA + P+ +G+VA Q
Sbjct: 221 GKNGATLDKFPKHVL----PGS--FDFGFPVGSVCKDIGLAVDECQALGVPMWVGSVARQ 274
Query: 96 LYRIVQSRGYGQKDFSFVFQLLKR 25
++ + +D + + + ++R
Sbjct: 275 MWNYAAMQDGAARDMTELVKYVER 298
>UniRef50_Q8U2W2 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=17;
Pyrococcus|Rep: 3-hydroxyisobutyrate dehydrogenase -
Pyrococcus furiosus
Length = 278
Score = 99 bits (238), Expect = 5e-20
Identities = 58/207 (28%), Positives = 101/207 (48%)
Frame = -3
Query: 648 KGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFER 469
+G + +D++T + I G + ++PV G V+ A+N L + G +E FER
Sbjct: 77 RGKIIVDTTTNHHEKVLEFHEIYRNVGAFYLESPVIGSVIPARNGQLTILVSGEREAFER 136
Query: 468 SLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVL 289
P L+ +G + F+ + G KL NN ++G A E + +G K GL + ++++L
Sbjct: 137 VRPYLQKLGKRIFYFNEPGKATKLKLINNFVLGAFMAALGEAIALGEKAGLSREEIIEIL 196
Query: 288 NNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGA 109
N + S V T + +Y F + +VKDL A +A+ R +PL A
Sbjct: 197 ENGAGNSM-------VLSAKKTKLLNDDYSTHFSVKNLVKDLSYAYDLAVASRKAVPLNA 249
Query: 108 VATQLYRIVQSRGYGQKDFSFVFQLLK 28
++YR+ +G + DFS V++L +
Sbjct: 250 TVREIYRLAFEKGLEELDFSVVYRLFR 276
>UniRef50_Q4WXG9 Cluster: 3-hydroxyisobutyrate dehydrogenase,
putative; n=1; Aspergillus fumigatus|Rep:
3-hydroxyisobutyrate dehydrogenase, putative -
Aspergillus fumigatus (Sartorya fumigata)
Length = 317
Score = 99.5 bits (237), Expect = 6e-20
Identities = 68/186 (36%), Positives = 96/186 (51%), Gaps = 2/186 (1%)
Frame = -3
Query: 639 LXIDSSTIDPNVPKQIFPIALE--KGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERS 466
+ +D STID + + K F DAPVSGG +GA TL FM G ++D
Sbjct: 112 ILVDCSTIDTATSMDVGAAVCQNSKTAAFYDAPVSGGSLGAVAGTLTFMVGCVEDD---- 167
Query: 465 LPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLN 286
P L+++ F CG G AKL NN G+ +ATAE MN+GIK G++P +L V
Sbjct: 168 -PNLELL---IFPCGGFLLGLTAKLCNNYCSGLIAIATAEAMNIGIKSGMKPSLLARVFA 223
Query: 285 NSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAV 106
S+A+S + + PVPG + P + +LM KDL LA A + + + LG
Sbjct: 224 TSTAQSTINDKWNPVPGCLSECPGEQGV------QLMKKDLALAVEAADRVGAQLRLGVP 277
Query: 105 ATQLYR 88
A Q+Y+
Sbjct: 278 ALQVYQ 283
>UniRef50_A0JXR2 Cluster: 2-hydroxy-3-oxopropionate reductase; n=2;
Arthrobacter|Rep: 2-hydroxy-3-oxopropionate reductase -
Arthrobacter sp. (strain FB24)
Length = 333
Score = 99.1 bits (236), Expect = 8e-20
Identities = 56/175 (32%), Positives = 89/175 (50%)
Frame = -3
Query: 555 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNML 376
DAPVSGG GA++ TLA M G ++DF+R LPL MG G +GSG +AK N ++
Sbjct: 136 DAPVSGGTKGAEDGTLAIMVGAGEQDFQRLLPLFNAMGGTVRRLGPLGSGSLAKACNQLI 195
Query: 375 MGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDG 196
+G T A AE + + G++ L ++L A S ++ P ++R+Y+
Sbjct: 196 VGTTTAALAEAAELAERSGMDVAALYELLAGGLAGSRVLDIVGP-------RLAARDYEP 248
Query: 195 GFKNELMVKDLELASGMALGIRSPIPLGAVATQLYRIVQSRGYGQKDFSFVFQLL 31
+ M KDL A + + +P+ V +LY ++ +G G D + V Q +
Sbjct: 249 TGPAKFMHKDLSFVLESAAAVDAAVPMATVGAELYAELKRQGLGDLDLAAVRQTI 303
>UniRef50_Q5L168 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=15;
Bacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Geobacillus kaustophilus
Length = 288
Score = 98.7 bits (235), Expect = 1e-19
Identities = 61/196 (31%), Positives = 100/196 (51%)
Frame = -3
Query: 657 HAKKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKED 478
+A+ G+ ID +T P + + I+ A +KG+ DAPVSGG +GA+ TL M GG ++
Sbjct: 84 NARPGTYVIDMTTSTPTLAQSIYEAAKQKGIHALDAPVSGGDIGAREGTLTIMVGGDEDV 143
Query: 477 FERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLL 298
F P+L+ +G G G+GQ K+ N + + + E M + GL+P +L
Sbjct: 144 FLACKPILERLGTNIVRQGGAGAGQHTKMCNQIAIATNMIGVCEAMAYAKRAGLDPFKVL 203
Query: 297 DVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIP 118
+ + +A SWS + L P S ++ GF + +KD+++A A + P+P
Sbjct: 204 ESIAKGAAGSWS------LSNLAPRMLSG-DFAPGFYVKHFIKDMKIALEEAERMNLPLP 256
Query: 117 LGAVATQLYRIVQSRG 70
A+A QLY + G
Sbjct: 257 GLALAKQLYEELAQAG 272
>UniRef50_A4IN46 Cluster: 3-hydroxyisobutyrate dehydrogenase-like
protein; n=2; Geobacillus|Rep: 3-hydroxyisobutyrate
dehydrogenase-like protein - Geobacillus
thermodenitrificans (strain NG80-2)
Length = 304
Score = 98.7 bits (235), Expect = 1e-19
Identities = 65/211 (30%), Positives = 102/211 (48%)
Frame = -3
Query: 654 AKKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDF 475
A++G + +D +T+ P + + A E+G+ + DAPVSGG GA+ TL M GG + +
Sbjct: 85 ARRGVICLDFTTVGPKTSRFVAGRAGERGVAYLDAPVSGGPEGAEQGTLTIMVGGDQAAW 144
Query: 474 ERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLD 295
ER PLL V+G + G+ G+G AK+ N L+ + +A AE M G+ GL+ L
Sbjct: 145 ERVRPLLSVLGKTVEYLGESGAGSAAKILNQYLVAVHSVAAAEAMVAGVAYGLDAGKLYR 204
Query: 294 VLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPL 115
+L S S + ++P R + G + + KD+ LA+ I L
Sbjct: 205 LLKESYGDSRMLRRHME-QFVLP-----RQFAPGGAVKYVHKDVRLANAFMNEIGINRCL 258
Query: 114 GAVATQLYRIVQSRGYGQKDFSFVFQLLKRR 22
G A + + G D S V QL +R+
Sbjct: 259 GVEAEETFAAAMDAGLADLDMSAVIQLFERQ 289
>UniRef50_A3SJ77 Cluster: Probable oxidoreductase; n=1; Roseovarius
nubinhibens ISM|Rep: Probable oxidoreductase -
Roseovarius nubinhibens ISM
Length = 320
Score = 98.7 bits (235), Expect = 1e-19
Identities = 66/210 (31%), Positives = 97/210 (46%)
Frame = -3
Query: 654 AKKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDF 475
A G+L I+ STI P I KGL DAPV AQN L MAGGR EDF
Sbjct: 95 AAPGTLVIEMSTISPEASLDIHDALTSKGLRVLDAPVGRTPKDAQNGALLIMAGGRAEDF 154
Query: 474 ERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLD 295
+ P+ + K H G GSG K+ NN + ++ + TAE + M K G++ ++
Sbjct: 155 ADAAPVFAPLADKIVHLGPKGSGIRMKIANNYMSMVSMVLTAETLAMARKAGIDTDAAVE 214
Query: 294 VLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPL 115
VL N++A V P L + F + KD+ L G+ + P+ L
Sbjct: 215 VLQNTTAGRGQINVNYPKKVL------RGDISPDFPLAMGAKDISLGVGLGKSLGVPLFL 268
Query: 114 GAVATQLYRIVQSRGYGQKDFSFVFQLLKR 25
GA A +L+ + S+ D + + L++R
Sbjct: 269 GANAGELFNLAASQDIRDWDCTAMLVLIER 298
>UniRef50_Q7WG50 Cluster: Probable oxidoreductase; n=1; Bordetella
bronchiseptica|Rep: Probable oxidoreductase - Bordetella
bronchiseptica (Alcaligenes bronchisepticus)
Length = 316
Score = 98.3 bits (234), Expect = 1e-19
Identities = 63/207 (30%), Positives = 102/207 (49%), Gaps = 1/207 (0%)
Frame = -3
Query: 645 GSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERS 466
G+L I+ STI P I E+G+ D+PV M AQ TL +A G +D R+
Sbjct: 90 GALFINMSTILPQETDLIAQRLAERGMRMLDSPVGRSAMEAQRGTLLILASGSAQDKARA 149
Query: 465 LPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGIT-GMATAECMNMGIKMGLEPKVLLDVL 289
L MG + CG++G G K+ NN MGI+ TAE + + GL ++ L+V+
Sbjct: 150 RDALLCMGNQVIDCGEVGGGSRVKVVNN-FMGISLNALTAEALTLAEASGLSVELALEVM 208
Query: 288 NNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGA 109
+ A + P + GF+ +L KDL LA +A R+ +P+G+
Sbjct: 209 RGTIAGLGHMNI------TYPNKVLRGDLSAGFQVDLAHKDLGLALELAARSRACVPMGS 262
Query: 108 VATQLYRIVQSRGYGQKDFSFVFQLLK 28
A Q Y +++G G +D+S ++ +++
Sbjct: 263 AAFQSYTAARAQGRGGQDYSAIYPVMR 289
>UniRef50_Q0RCX7 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Frankia alni ACN14a|Rep: 3-hydroxyisobutyrate
dehydrogenase - Frankia alni (strain ACN14a)
Length = 313
Score = 98.3 bits (234), Expect = 1e-19
Identities = 65/204 (31%), Positives = 96/204 (47%)
Frame = -3
Query: 645 GSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERS 466
G+ +D +T + +I A E G+GF DAPVSGG GA+ L+ M GG + ER
Sbjct: 88 GATIVDHTTTSAELAVEIAARAAEVGVGFVDAPVSGGQAGAEAGRLSVMCGGEVDTVERV 147
Query: 465 LPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLN 286
P+L GA G +G+GQ+ K+ N +L+ AE +N GL+ +L ++
Sbjct: 148 RPVLAAYGATITRIGPVGTGQLTKMVNQILVAGAIEGAAEALNFAAAAGLDLDQVLPAVS 207
Query: 285 NSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAV 106
+A SW + T +D GF + M KDL + A P+PL +
Sbjct: 208 GGAASSWY------LTNRAATMIRD-EFDFGFAVDWMRKDLRICLAEAARRGVPVPLTEL 260
Query: 105 ATQLYRIVQSRGYGQKDFSFVFQL 34
A Q+RG GQ D + V +L
Sbjct: 261 AEGDLAASQARGDGQLDATAVIRL 284
>UniRef50_A4SWE8 Cluster: 2-hydroxy-3-oxopropionate reductase
precursor; n=7; Proteobacteria|Rep:
2-hydroxy-3-oxopropionate reductase precursor -
Polynucleobacter sp. QLW-P1DMWA-1
Length = 299
Score = 98.3 bits (234), Expect = 1e-19
Identities = 67/214 (31%), Positives = 100/214 (46%), Gaps = 1/214 (0%)
Frame = -3
Query: 663 VAHA-KKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGR 487
VAH KG + +D S+I P K G + DAPVSGG +GA+ TL M GG+
Sbjct: 82 VAHGLSKGKIVVDMSSISPIATKDFAKKINALGCEYLDAPVSGGQVGAKGGTLTIMVGGK 141
Query: 486 KEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPK 307
+ F+ P+ +MG G G+GQV K+ N +++ + A AE + K G +P
Sbjct: 142 ESVFQTVKPMFDLMGKNITLVGDNGAGQVTKVANQIIVALNIEAVAEALLFASKAGADPA 201
Query: 306 VLLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRS 127
+ + L A S EV+ R +D GF+ EL KDL LA A +
Sbjct: 202 RVREALMGGFASSKILEVHA-------ERMIKRTFDPGFRIELHQKDLNLALNSARALGV 254
Query: 126 PIPLGAVATQLYRIVQSRGYGQKDFSFVFQLLKR 25
+P A A +L+ + G D S + + L++
Sbjct: 255 SLPNTANAQELFNSCLAYGGKAWDHSAMVKALEK 288
>UniRef50_A3K497 Cluster: Probable 6-phosphogluconate dehydrogenase
protein; n=1; Sagittula stellata E-37|Rep: Probable
6-phosphogluconate dehydrogenase protein - Sagittula
stellata E-37
Length = 298
Score = 98.3 bits (234), Expect = 1e-19
Identities = 59/178 (33%), Positives = 99/178 (55%), Gaps = 3/178 (1%)
Frame = -3
Query: 645 GSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKED-FER 469
G+L ID+++ P +++ + +G DAPVSG GA+ A L FM G + ER
Sbjct: 92 GTLMIDTTSSPPEATRELAAVLNARGCHLVDAPVSGARAGAEAADLVFMIGCDDDAVLER 151
Query: 468 SLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVL 289
+ +L +G + FH G +G+G K NN + +A AE M +G ++GL+P ++DVL
Sbjct: 152 TRAVLSCLGNRLFHLGPVGAGHAMKALNNYVSAAGYVAAAEAMIIGTEVGLDPAQIVDVL 211
Query: 288 NNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELAS--GMALGIRSPI 121
N S+ R++STEV +P ++ +++ F EL KD+ +A+ G G+ +P+
Sbjct: 212 NVSTGRNFSTEV--SMPRIL-----RGDFERRFTLELYTKDVRIAANLGDRAGVTAPL 262
>UniRef50_Q3W9W7 Cluster: 6-phosphogluconate dehydrogenase, NAD
binding domain; n=2; Frankia sp. EAN1pec|Rep:
6-phosphogluconate dehydrogenase, NAD binding domain -
Frankia sp. EAN1pec
Length = 286
Score = 97.9 bits (233), Expect = 2e-19
Identities = 61/182 (33%), Positives = 90/182 (49%), Gaps = 1/182 (0%)
Frame = -3
Query: 633 IDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLL 454
+D+STI + ++I + G+G+ DAPVSGGV GA+ TL M G + R P+L
Sbjct: 89 VDTSTIGVSAAQRITDLLAASGIGYVDAPVSGGVTGARARTLTVMYAGTDDACARVEPVL 148
Query: 453 KVMGAKQFHCG-QIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSS 277
+ ++ G + G Q KL NN L + AT+E + G GL+ +LDVLN +S
Sbjct: 149 AALSDRRRRVGDRPGLAQALKLANNFLAAVALAATSEAVAFGTSAGLDMGTMLDVLNTAS 208
Query: 276 ARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVATQ 97
++ +T P L + Y GF N LM KDL L + P LG V +
Sbjct: 209 GQNNATAEKFPRQVL------TERYSAGFANSLMAKDLRLYLQEVRELDGPTSLGTVTSS 262
Query: 96 LY 91
++
Sbjct: 263 VW 264
>UniRef50_Q94B07 Cluster: Gamma hydroxybutyrate dehydrogenase; n=16;
cellular organisms|Rep: Gamma hydroxybutyrate
dehydrogenase - Arabidopsis thaliana (Mouse-ear cress)
Length = 289
Score = 97.5 bits (232), Expect = 3e-19
Identities = 68/209 (32%), Positives = 105/209 (50%), Gaps = 2/209 (0%)
Frame = -3
Query: 648 KGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFER 469
+G ID ST+D +I KG F + PVSG A++ L +A G K FE
Sbjct: 86 EGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPVSGSKKPAEDGQLIILAAGDKALFEE 145
Query: 468 SLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVL 289
S+P V+G + F+ GQ+G+G KL NM+MG A +E + + K GL LLD+L
Sbjct: 146 SIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSMMNAFSEGLVLADKSGLSSDTLLDIL 205
Query: 288 NNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPI--PL 115
+ + + ++ G P+ S +Y F + KD+ LA +ALG + + P+
Sbjct: 206 D---LGAMTNPMF---KGKGPSMTKS-SYPPAFPLKHQQKDMRLA--LALGDENAVSMPV 256
Query: 114 GAVATQLYRIVQSRGYGQKDFSFVFQLLK 28
A A + ++ +S G G DFS V + +K
Sbjct: 257 AAAANEAFKKARSLGLGDLDFSAVIEAVK 285
>UniRef50_A1WM48 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Verminephrobacter eiseniae EF01-2|Rep:
3-hydroxyisobutyrate dehydrogenase - Verminephrobacter
eiseniae (strain EF01-2)
Length = 301
Score = 97.1 bits (231), Expect = 3e-19
Identities = 66/209 (31%), Positives = 103/209 (49%), Gaps = 1/209 (0%)
Frame = -3
Query: 651 KKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFE 472
K+ +D STI P +G+ + D+PVSGG+ GA+ TLA M + ++
Sbjct: 88 KRVKCVVDLSTIGPRAAVAASQALGARGIAYVDSPVSGGIGGAERGTLAVMTACPQPLYD 147
Query: 471 RSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDV 292
P+LK G + G GQ KL NN+L T+E M MG K GL+P V+L+V
Sbjct: 148 ELAPVLKNFGRLFYMGAGPGLGQTMKLANNLLSAAAVAITSEAMAMGAKAGLDPGVMLEV 207
Query: 291 LNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLG 112
+N S R+ +T P L T ++ GF L KD+ L + + P+ +G
Sbjct: 208 INAGSGRNSATMEKFPKAVLTGT------FNIGFAARLACKDVRLCLEESEALGVPMVVG 261
Query: 111 AVATQLYRIVQSRGYGQ-KDFSFVFQLLK 28
A ++ +V + YG+ D++ V +LL+
Sbjct: 262 AAVREML-VVTNAVYGKDADYTDVARLLE 289
>UniRef50_Q39FA8 Cluster: 2-hydroxy-3-oxopropionate reductase; n=22;
Burkholderiales|Rep: 2-hydroxy-3-oxopropionate reductase
- Burkholderia sp. (strain 383) (Burkholderia cepacia
(strain ATCC 17760/ NCIB 9086 / R18194))
Length = 287
Score = 96.3 bits (229), Expect = 6e-19
Identities = 64/211 (30%), Positives = 101/211 (47%)
Frame = -3
Query: 660 AHAKKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKE 481
A A++ +D S+I P + A G+G+ DAPVSGGV GAQ TLA MAGGR
Sbjct: 75 AAARRLQRIVDHSSIPPAATRDYAARATALGVGWVDAPVSGGVPGAQAGTLAVMAGGRAA 134
Query: 480 DFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVL 301
D + PL+ ++ H G G+GQ AKL N ++ T A AE + + G++ L
Sbjct: 135 DLDAVRPLIDTYASRITHMGDAGAGQTAKLCNQAIVTATVTAIAEAVGLAQASGIDAARL 194
Query: 300 LDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPI 121
+ L A W+ V + VP S + G + KD++ + A + +
Sbjct: 195 AEAL----AGGWADSVL--LQTFVPRMTSGGHPPIGALSTFQ-KDVDAIADAARDTGAVM 247
Query: 120 PLGAVATQLYRIVQSRGYGQKDFSFVFQLLK 28
P+ A Q+ R+ ++G DF+ +++
Sbjct: 248 PVSATVQQVLRLGAAQGLAGADFAAFIDIVR 278
>UniRef50_A3WMG5 Cluster: Probable 3-hydroxyisobutyrate
dehydrogenase; n=1; Idiomarina baltica OS145|Rep:
Probable 3-hydroxyisobutyrate dehydrogenase - Idiomarina
baltica OS145
Length = 284
Score = 96.3 bits (229), Expect = 6e-19
Identities = 64/204 (31%), Positives = 105/204 (51%), Gaps = 1/204 (0%)
Frame = -3
Query: 642 SLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERSL 463
++ I+SST+ + K++ A ++G +APVSG AQNA L ++ GG R+
Sbjct: 90 AIAIESSTLSVDWVKELAQQAQQRGKQLIEAPVSGSRPQAQNAELVYLVGGDAHLVNRAE 149
Query: 462 PLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNN 283
P+L +MG K H G++GSG +AKL N LMGI AE + M + G +P +L+ ++
Sbjct: 150 PVLSLMGKKVNHTGEMGSGALAKLVTNTLMGIQVTTIAELIGMLKRQGQDPDAILEAVS- 208
Query: 282 SSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPI-PLGAV 106
+T V+ G+V + S YD F +L+ KDL G L + P+ +
Sbjct: 209 ------TTPVWSKTAGIVRKSMVSEAYDPQFPVDLIEKDL----GYCLQAADQVAPMTSA 258
Query: 105 ATQLYRIVQSRGYGQKDFSFVFQL 34
A ++ Q + G+ + + V +L
Sbjct: 259 ARTVFNEAQEQQLGEWNMTVVAKL 282
>UniRef50_A3EW86 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Leptospirillum sp. Group II UBA|Rep:
3-hydroxyisobutyrate dehydrogenase - Leptospirillum sp.
Group II UBA
Length = 279
Score = 96.3 bits (229), Expect = 6e-19
Identities = 65/210 (30%), Positives = 102/210 (48%)
Frame = -3
Query: 651 KKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFE 472
+ GSL I+ STI P ++ L KG G+ D PVSG ++ A+ L +AGG E
Sbjct: 73 RPGSLVINMSTIAPEEAQEEALSLLAKGAGYLDVPVSGSLVPAEKGELLLLAGGDGAALE 132
Query: 471 RSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDV 292
R+ P+L G K H G GSG AKL N+L+ + + + +G +GL+ +L +
Sbjct: 133 RARPILLHFGKKILHFGPTGSGMKAKLVINLLLASHVESLVQTVLVGESLGLDGHQVLGM 192
Query: 291 LNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLG 112
+ +S + P + R+YD F LM KDL+L S L R+P L
Sbjct: 193 ILDSPLAT-------PFYQIKRANLEKRSYDKAFSARLMAKDLDLLSLTLLRNRTPASLP 245
Query: 111 AVATQLYRIVQSRGYGQKDFSFVFQLLKRR 22
+ +R + G G++D S +++ + R
Sbjct: 246 FELGRHFRELVESGRGEEDVSALYEYFRDR 275
>UniRef50_Q019Z7 Cluster: Oxidoreductase-like; n=1; Ostreococcus
tauri|Rep: Oxidoreductase-like - Ostreococcus tauri
Length = 325
Score = 96.3 bits (229), Expect = 6e-19
Identities = 67/218 (30%), Positives = 101/218 (46%), Gaps = 5/218 (2%)
Frame = -3
Query: 663 VAHAKKGSLX-----IDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFM 499
VAHA K L +D ST+D + I + G F +APVSG A++ L F+
Sbjct: 115 VAHAAKEGLSSGKGYVDVSTVDAGTSRAIAEVVRSTGAEFLEAPVSGSKKPAEDGALIFL 174
Query: 498 AGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMG 319
G + + R L VMG F G +G G KL NM+MG A AE + + K
Sbjct: 175 CAGDEGLYTRCTDPLDVMGKAHFFLGDVGQGAKMKLVVNMIMGSMMGAFAEGLTLADKSD 234
Query: 318 LEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMAL 139
L + LL V++ + S P+ L + + NY F + KD+ LA +A
Sbjct: 235 LSQETLLQVISLGAIAS-------PMFALKGPSMVAGNYPPAFPLKHQQKDMRLAIALAD 287
Query: 138 GIRSPIPLGAVATQLYRIVQSRGYGQKDFSFVFQLLKR 25
+ +P+ A A +LY+ + G +DFS V + +K+
Sbjct: 288 ELAQDMPVAAAANELYKRARRDGCDDEDFSAVLKAVKK 325
>UniRef50_Q73P00 Cluster: 3-hydroxyacid dehydrogenase family
protein; n=4; Bacteria|Rep: 3-hydroxyacid dehydrogenase
family protein - Treponema denticola
Length = 292
Score = 95.9 bits (228), Expect = 8e-19
Identities = 59/209 (28%), Positives = 101/209 (48%)
Frame = -3
Query: 654 AKKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDF 475
AK G++ D +T P + K+I+ A +K DAPVSGG +GA+N TL+ MAGG + F
Sbjct: 89 AKPGTIFADMTTSSPILAKKIYDEAKKKECFSVDAPVSGGDIGAKNGTLSIMAGGDESAF 148
Query: 474 ERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLD 295
+ P MG G G+GQ K+ N + + T E + GL+P +L
Sbjct: 149 KELEPFFACMGKTWALQGGAGAGQHTKMANQIAVAANLFGTVEAVCYAEAAGLDPHKMLS 208
Query: 294 VLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPL 115
+ +A SW ++ P ++ +++ GF + +KDL + +A ++ IP+
Sbjct: 209 AIGGGAAGSW--QILNNGPKML-----QKDFAPGFYIKHFLKDLNITLNVAKELKLHIPV 261
Query: 114 GAVATQLYRIVQSRGYGQKDFSFVFQLLK 28
+A + + GY +K +++ K
Sbjct: 262 LELAQNFFNKMNEEGYAEKGTQAIYEYYK 290
>UniRef50_A0GI22 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Burkholderia phytofirmans PsJN|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Burkholderia phytofirmans PsJN
Length = 355
Score = 95.9 bits (228), Expect = 8e-19
Identities = 60/180 (33%), Positives = 89/180 (49%)
Frame = -3
Query: 567 LGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLT 388
+G+ DAPVSGGV GA TLA MAGG D E PLL ++ H G +G+GQ AKL
Sbjct: 175 IGWIDAPVSGGVAGATAGTLAVMAGGAAADVEAVKPLLGAYASRVTHMGDVGAGQTAKLC 234
Query: 387 NNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSSR 208
N ++ T A AE +++ + GL+ L + L A S + + P AP
Sbjct: 235 NQTIVTATLAAIAEAVSLAQRSGLDASRLTEGLAGGWADSVLLQTFVPRMTQTGLAPI-- 292
Query: 207 NYDGGFKNELMVKDLELASGMALGIRSPIPLGAVATQLYRIVQSRGYGQKDFSFVFQLLK 28
G F+ KD++ + A +P+P+ + QL R+ + G G+ D S +L+
Sbjct: 293 ---GAFRT--FQKDIDTVAATAYETGTPMPVSSTVQQLLRLGAAMGLGEADLSAFIDVLQ 347
>UniRef50_Q7VYY0 Cluster: Putative oxidoreductase; n=4;
Bordetella|Rep: Putative oxidoreductase - Bordetella
pertussis
Length = 305
Score = 95.5 bits (227), Expect = 1e-18
Identities = 66/215 (30%), Positives = 102/215 (47%)
Frame = -3
Query: 651 KKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFE 472
+ G+ +D + +P +++ +GL DAPVSG V A TLA MAG + D
Sbjct: 95 ESGAAIVDMGSSNPADTRRLSEQLAARGLTLIDAPVSGAVAKASTGTLAIMAGAAEADLR 154
Query: 471 RSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDV 292
R P+L+ MGA H G +GS K NN + +A +E M + +M L+ +V DV
Sbjct: 155 RVRPILERMGAAIIHTGAVGSAHAMKALNNYVYAAGLLAVSEAMVIARRMELDLEVFTDV 214
Query: 291 LNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLG 112
LN SS R+ ++E ++P Y+GGF LM KDL A +
Sbjct: 215 LNASSGRNVASETKLR-QFIIP-----GTYNGGFALALMAKDLGTAQSLQALTGVQADQL 268
Query: 111 AVATQLYRIVQSRGYGQKDFSFVFQLLKRRKQKLE 7
A+ +L+R ++ G D + + + L +R E
Sbjct: 269 ALCAELWRQALAQLPGGADNTEIHRFLAQRTPATE 303
>UniRef50_A5P0V0 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding precursor; n=3; Rhizobiales|Rep:
6-phosphogluconate dehydrogenase, NAD-binding precursor
- Methylobacterium sp. 4-46
Length = 299
Score = 95.5 bits (227), Expect = 1e-18
Identities = 63/195 (32%), Positives = 98/195 (50%), Gaps = 1/195 (0%)
Frame = -3
Query: 624 STIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVM 445
+T P + + G F DAPVSGGV+GA+ +L MA E F PLL +
Sbjct: 101 ATCPPQAVEGLAARVAAAGRRFVDAPVSGGVVGAEAGSLTVMAAAPAEVFGAVRPLLDAV 160
Query: 444 GAKQFHCG-QIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARS 268
GA+ FH G + G G K N +L G+ A AE +++ ++G++ V+L++L+ SSA S
Sbjct: 161 GARIFHVGTRPGQGATVKAVNQLLCGVHIAAAAEALSLAERVGVDLPVVLEILSGSSAAS 220
Query: 267 WSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVATQLYR 88
W + P ++ AP + ++ VKDL + ++ +PL ++A QL+
Sbjct: 221 WM--LRDRGPRMLEEAPRVTS-----AVDIFVKDLGIVLEAGRDQKAALPLASLAHQLFL 273
Query: 87 IVQSRGYGQKDFSFV 43
RG G D S V
Sbjct: 274 AASGRGEGAADDSQV 288
>UniRef50_A7PEG7 Cluster: Chromosome chr11 scaffold_13, whole genome
shotgun sequence; n=2; Vitis vinifera|Rep: Chromosome
chr11 scaffold_13, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 348
Score = 95.1 bits (226), Expect = 1e-18
Identities = 66/209 (31%), Positives = 103/209 (49%)
Frame = -3
Query: 651 KKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFE 472
+ G + +D +T DP++ +I A +G DAPVSGG GA+NATLA AGG +
Sbjct: 134 RPGGVLVDMTTSDPSLAAEIASSAASRGCFSVDAPVSGGDRGAKNATLAIFAGGDESVVR 193
Query: 471 RSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDV 292
R PL +G K + G G GQ AKL N +++ T + E M K GL+ + L+
Sbjct: 194 RLNPLFSHLG-KVNYMGGPGKGQYAKLANQIIIASTMLGLIEGMMYAYKSGLDVALFLNA 252
Query: 291 LNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLG 112
++ +A S S ++Y + R+++ GF VKDL + + +P
Sbjct: 253 ISTGAAGSKSLDLY-------GSRILKRDFEAGFFVNHFVKDLGICLIECQKMGLSLPGL 305
Query: 111 AVATQLYRIVQSRGYGQKDFSFVFQLLKR 25
A+A QLY +++ G G + L+R
Sbjct: 306 ALAQQLYLSLKAHGEGNLGTQALILTLER 334
>UniRef50_A6GTB5 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding protein; n=1; Limnobacter sp. MED105|Rep:
6-phosphogluconate dehydrogenase, NAD-binding protein -
Limnobacter sp. MED105
Length = 299
Score = 94.7 bits (225), Expect = 2e-18
Identities = 68/211 (32%), Positives = 100/211 (47%)
Frame = -3
Query: 657 HAKKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKED 478
HA+ GS+ +D STID I +G+ + D PVSGG GA+ ATL+ MAGG
Sbjct: 91 HAQPGSIIVDFSTIDAAAVADIARQLKSRGVDYIDCPVSGGAAGARAATLSMMAGGDLAA 150
Query: 477 FERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLL 298
F R P+LK +G H G G+GQ K N M + I + AE MN ++ G E V+L
Sbjct: 151 FNRIEPMLKHLGKTIRHVGPSGAGQAIKAANQMALCIQLVGIAEAMNYALEQGAELSVVL 210
Query: 297 DVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIP 118
++L S + P T P S + L KD+ + + A +P
Sbjct: 211 ELLQAGLPASRVLDWAGPHMVKGFTDPVS------IEAHLHAKDVRMVADAAKKQGLHLP 264
Query: 117 LGAVATQLYRIVQSRGYGQKDFSFVFQLLKR 25
L +L + + G +D S VF++++R
Sbjct: 265 LLFKTAELLDELVASGPKSQDTSRVFEVVRR 295
>UniRef50_Q1IQE6 Cluster: 2-hydroxy-3-oxopropionate reductase
precursor; n=1; Acidobacteria bacterium Ellin345|Rep:
2-hydroxy-3-oxopropionate reductase precursor -
Acidobacteria bacterium (strain Ellin345)
Length = 282
Score = 94.3 bits (224), Expect = 2e-18
Identities = 57/209 (27%), Positives = 98/209 (46%)
Frame = -3
Query: 651 KKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFE 472
+ G + +DSSTI P + KG + DAP++G +GA++A L FM G + E +
Sbjct: 80 RAGMVVVDSSTISPVETLKFAERVRAKGADYIDAPITGSKIGAESAQLIFMVGAKDETLK 139
Query: 471 RSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDV 292
+ PL MG K H G++G GQ +K++ N+ + E + ++G+ P+ +++
Sbjct: 140 KLEPLFLQMGKKIVHMGEVGKGQASKISLNLQIACIYEGFIEGFKVATQLGVNPEKFVEL 199
Query: 291 LNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLG 112
+ ++ RS + P R+Y F LM KDL L S A + +P
Sbjct: 200 VQSTMVRSGVVDYKAPF-------VLKRDYTPNFPLRLMRKDLLLVSDAAKQLELDLPGL 252
Query: 111 AVATQLYRIVQSRGYGQKDFSFVFQLLKR 25
++Y G +D++ LL+R
Sbjct: 253 KSVLEVYDEAHEAGMDDQDYAATLALLER 281
>UniRef50_P77161 Cluster: 2-hydroxy-3-oxopropionate reductase; n=99;
Proteobacteria|Rep: 2-hydroxy-3-oxopropionate reductase
- Escherichia coli (strain K12)
Length = 292
Score = 94.3 bits (224), Expect = 2e-18
Identities = 65/207 (31%), Positives = 95/207 (45%)
Frame = -3
Query: 648 KGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFER 469
KG +D S+I P K+ E G + DAPVSGG +GA+ TL+ M GG + FER
Sbjct: 85 KGKTIVDMSSISPIETKRFARQVNELGGDYLDAPVSGGEIGAREGTLSIMVGGDEAVFER 144
Query: 468 SLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVL 289
PL +++G G G GQ K+ N +++ + A +E + K G +P + L
Sbjct: 145 VKPLFELLGKNITLVGGNGDGQTCKVANQIIVALNIEAVSEALLFASKAGADPVRVRQAL 204
Query: 288 NNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGA 109
A S EV+ R ++ GFK L KDL LA A + +P A
Sbjct: 205 MGGFASSRILEVH-------GERMIKRTFNPGFKIALHQKDLNLALQSAKALALNLPNTA 257
Query: 108 VATQLYRIVQSRGYGQKDFSFVFQLLK 28
+L+ + G Q D S + Q L+
Sbjct: 258 TCQELFNTCAANGGSQLDHSALVQALE 284
>UniRef50_Q0F1Y7 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding protein; n=1; Mariprofundus ferrooxydans
PV-1|Rep: 6-phosphogluconate dehydrogenase, NAD-binding
protein - Mariprofundus ferrooxydans PV-1
Length = 289
Score = 93.9 bits (223), Expect = 3e-18
Identities = 64/209 (30%), Positives = 95/209 (45%)
Frame = -3
Query: 648 KGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFER 469
+G I+ ST+ K+ + G+ DAPVSG + AQ TL +AGG +
Sbjct: 88 EGKTVINMSTVPVECSKRWAKELADHGMTLIDAPVSGSKVPAQTGTLVILAGGPEAAVRA 147
Query: 468 SLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVL 289
PLL MG K +CG GSG KL N+L+GI AE +++ GL + LLD +
Sbjct: 148 QEPLLLSMGKKVIYCGPTGSGSAMKLAINLLLGIMTEGIAEALHLAESSGLASETLLDAV 207
Query: 288 NNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGA 109
S + C + L + NY F + M KD++ A + +PLG
Sbjct: 208 A-------SGPLSCTLFHLKEEMFKTGNYPPQFPFKHMAKDMQFVLAAAAENGAHLPLGT 260
Query: 108 VATQLYRIVQSRGYGQKDFSFVFQLLKRR 22
+L+ ++DF+ V LL+RR
Sbjct: 261 ELAKLFSPAADADLQEQDFAAVKTLLERR 289
>UniRef50_A7IE35 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2;
Proteobacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Xanthobacter sp. (strain Py2)
Length = 330
Score = 93.5 bits (222), Expect = 4e-18
Identities = 58/208 (27%), Positives = 98/208 (47%), Gaps = 1/208 (0%)
Frame = -3
Query: 645 GSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERS 466
G++ + S+T+DP + + + G + DAP+SGG A L +A G F ++
Sbjct: 119 GAVFLSSATMDPEIARTLAARLEATGRLYLDAPISGGAQRAAEGALTILASGSPAAFAKA 178
Query: 465 LPLLKVMGAKQFHCGQI-GSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVL 289
P L M AK + G G G K+ N +L G+ A +E + + GL+ + +V+
Sbjct: 179 RPALDAMAAKLYELGDAPGQGAAFKMINQLLAGVHIAAASEAVAFAARQGLDIAKVYEVI 238
Query: 288 NNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGA 109
S+ SW E +P +V +Y ++ VKDL + MA + P+P+ A
Sbjct: 239 TASAGNSWMFE--NRMPHVV-----DGDYTPRSAVDIFVKDLGIIQDMARSAKFPVPVSA 291
Query: 108 VATQLYRIVQSRGYGQKDFSFVFQLLKR 25
A Q++ + G G+ D + V +L R
Sbjct: 292 AALQMFLATSAAGMGRDDDASVARLYAR 319
>UniRef50_Q8PK98 Cluster: 3-hydroxyisobutirate dehydrogenase; n=3;
Proteobacteria|Rep: 3-hydroxyisobutirate dehydrogenase -
Xanthomonas axonopodis pv. citri
Length = 300
Score = 93.1 bits (221), Expect = 5e-18
Identities = 64/207 (30%), Positives = 98/207 (47%), Gaps = 1/207 (0%)
Frame = -3
Query: 639 LXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLP 460
L +D ST ++ + + F APVSGG A L MA G +ER+ P
Sbjct: 91 LVVDLSTTGAQTTSEVGHLLERADVSFLSAPVSGGTAAAAQGVLTVMAAGPLAAYERARP 150
Query: 459 LLKVMGAKQFHCG-QIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNN 283
LL +G F+ G + GQ KL NN L +A+ E + G K GL+ + +LDV+N
Sbjct: 151 LLDAVGRHIFYLGGDVRLGQTLKLINNTLYASAMLASCEALVCGAKAGLDARTMLDVINR 210
Query: 282 SSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVA 103
SS R ++T + G + R++ F EL+ KD++L A + P+ +G A
Sbjct: 211 SSGRCFATME--RLHGAL-----DRSFPVRFTTELLRKDVQLGLMAADELGVPMHVGKAA 263
Query: 102 TQLYRIVQSRGYGQKDFSFVFQLLKRR 22
QL + G G+ D Q ++R+
Sbjct: 264 LQLLDQAVADGLGEADNIAAIQSIERQ 290
>UniRef50_Q121N3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=19;
Burkholderiales|Rep: 3-hydroxyisobutyrate dehydrogenase
- Polaromonas sp. (strain JS666 / ATCC BAA-500)
Length = 298
Score = 92.3 bits (219), Expect = 1e-17
Identities = 57/207 (27%), Positives = 99/207 (47%), Gaps = 1/207 (0%)
Frame = -3
Query: 651 KKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFE 472
K GS+ + ST+DP + G+ + DAP+SGG A + M+ R +E
Sbjct: 88 KSGSVFVMCSTVDPQWSIATEARLDKLGIHYVDAPISGGAAKAAAGQMTVMSSARPAAYE 147
Query: 471 RSLPLLKVMGAKQFHCGQ-IGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLD 295
++ +L M K + G G+G K+ N +L G+ A AE M +G++ G++P L +
Sbjct: 148 KAGDVLAAMAGKVYRLGDCAGAGSKVKIINQLLAGVHIAAAAEAMALGLREGVDPNALYE 207
Query: 294 VLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPL 115
V+ +S+ SW E + +Y ++ VKDL L A + P+PL
Sbjct: 208 VITHSAGNSWMFENRM-------AHVLAGDYTPLSAVDIFVKDLGLVLDTARASKFPLPL 260
Query: 114 GAVATQLYRIVQSRGYGQKDFSFVFQL 34
+ A Q++ + G+ ++D S V ++
Sbjct: 261 SSTAHQMFMQASTAGFAREDDSAVIKI 287
>UniRef50_A1R2J4 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Arthrobacter aurescens TC1|Rep: 3-hydroxyisobutyrate
dehydrogenase - Arthrobacter aurescens (strain TC1)
Length = 332
Score = 92.3 bits (219), Expect = 1e-17
Identities = 67/198 (33%), Positives = 94/198 (47%), Gaps = 2/198 (1%)
Frame = -3
Query: 645 GSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERS 466
G +D ST P V ++ +G+ DAPVSG +GA N L GG D ER
Sbjct: 110 GGTWVDMSTSVPEVANRVREAGSVRGIRVLDAPVSGMSVGAANGMLQIFVGGEPADVERL 169
Query: 465 LPLLKVMGAKQ--FHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDV 292
P+ + MG + H G G+G KL N L +ATAE ++ G+K G++ +VL
Sbjct: 170 RPVFEAMGDPERILHVGGHGAGYAVKLMINQLWFSHLVATAEVLSTGVKAGVDLEVLRQA 229
Query: 291 LNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLG 112
L S A S V V + + +YD GF L KDL L+ +A + P+ L
Sbjct: 230 LIASPANSNF------VQNDVLSILNHGDYDEGFAIALACKDLGLSVDLARSVGVPMELS 283
Query: 111 AVATQLYRIVQSRGYGQK 58
+ QLYR ++ YG K
Sbjct: 284 GLVEQLYRRAKAL-YGDK 300
>UniRef50_A3WAC4 Cluster: Dehydrogenase; n=4; Bacteria|Rep:
Dehydrogenase - Erythrobacter sp. NAP1
Length = 301
Score = 91.1 bits (216), Expect = 2e-17
Identities = 59/205 (28%), Positives = 101/205 (49%)
Frame = -3
Query: 663 VAHAKKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRK 484
+A K+G+ ID +++ P + ++I GL DAPVSGG GA+N L+ M GG +
Sbjct: 91 LAAMKRGATFIDHTSVSPGLARRIADECERLGLHAVDAPVSGGQAGAENGKLSIMCGGSE 150
Query: 483 EDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKV 304
E + P+++ A+ H G+ G+GQ AK N + + +E + + G++
Sbjct: 151 EAMASAQPVMQAYAARIVHIGEAGAGQTAKAINQVCIAGVLAGLSEGVRLAQATGVDTYK 210
Query: 303 LLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSP 124
+++ ++ +A+SW E P +V S +D GF + M KDL +A A
Sbjct: 211 VVEAISGGAAQSWQMENRWPT--MV-----SGEFDFGFAIDWMRKDLAIALEEAGKHGLD 263
Query: 123 IPLGAVATQLYRIVQSRGYGQKDFS 49
+ + + Q Y VQ+ G + D S
Sbjct: 264 MSVTKLVDQFYSEVQAAGGNRLDTS 288
>UniRef50_A5FTT0 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=3; Alphaproteobacteria|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Acidiphilium cryptum (strain JF-5)
Length = 305
Score = 90.2 bits (214), Expect = 4e-17
Identities = 61/176 (34%), Positives = 91/176 (51%), Gaps = 2/176 (1%)
Frame = -3
Query: 645 GSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERS 466
G+L I+ S+ P V ++I + DAPVSGGV A+ L+ M GG +D R+
Sbjct: 87 GALLIEMSSGIPGVTRRIAAGLEAAKVAMIDAPVSGGVARAKTGDLSIMTGGSADDCARA 146
Query: 465 LPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLN 286
LL++MG H G IG+GQ K NN++ + E + +G + GL+P ++DVLN
Sbjct: 147 ETLLRLMGTTITHVGDIGAGQAMKALNNLVSAGGFLIGVEALLIGQRFGLDPAQMVDVLN 206
Query: 285 NSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELA--SGMALGIRSP 124
S+ + ST+ L SR ++ F +LM KDL +A G GI +P
Sbjct: 207 ASTGMNNSTQKKFRQFVL------SRKFNSDFSLDLMAKDLSIALEVGRDGGIATP 256
>UniRef50_A6LT11 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=3; Clostridiales|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Clostridium beijerinckii
NCIMB 8052
Length = 291
Score = 89.8 bits (213), Expect = 5e-17
Identities = 53/168 (31%), Positives = 87/168 (51%)
Frame = -3
Query: 657 HAKKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKED 478
+AKK S ID +T P + +I+ A ++ + DAPVSGG +GA+NATL+ M GG E
Sbjct: 84 NAKKESCIIDMTTTSPKLSIKIYNEAKKREIYALDAPVSGGDVGAKNATLSIMVGGDLEV 143
Query: 477 FERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLL 298
FE+ +L +G + G+ G+GQ K+ N + + E + +GL+ + +L
Sbjct: 144 FEKHKDVLSALGTNIIYEGKAGNGQHTKMANQIALAGAIAGVCEAITYAKGVGLDVQTML 203
Query: 297 DVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELA 154
D ++ +A SW + P ++D GF + +KD+ LA
Sbjct: 204 DSISEGAAGSWQMKNMAP-------RMLKGDFDPGFYIKHFIKDMNLA 244
>UniRef50_A6P2M7 Cluster: Putative uncharacterized protein; n=2;
Bacteria|Rep: Putative uncharacterized protein -
Bacteroides capillosus ATCC 29799
Length = 321
Score = 89.4 bits (212), Expect = 7e-17
Identities = 59/200 (29%), Positives = 96/200 (48%)
Frame = -3
Query: 663 VAHAKKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRK 484
+++A+ G+L +D +T P + ++I+ KGL DAPV+GG GA+ TL+ + GG K
Sbjct: 116 ISNAQPGALIVDMTTSSPALAERIWEAGKAKGLRPLDAPVTGGDTGAKAGTLSILVGGDK 175
Query: 483 EDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKV 304
DF+ LPL + MG H G G+GQ AKL N + + E + GL
Sbjct: 176 VDFDACLPLFQAMGKIIVHMGSAGAGQHAKLANQIAIAGALSGVCEALTYARANGLNLDD 235
Query: 303 LLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSP 124
LL ++ +A S+ + P + AP GF + +KD++L+ + I
Sbjct: 236 LLSAISAGAAGSFQMQSLGPKMAVGDFAP-------GFIMKHFIKDMKLSVEQSETIGLA 288
Query: 123 IPLGAVATQLYRIVQSRGYG 64
+P+ R ++ G G
Sbjct: 289 LPVLTQVLSECRSLEEAGLG 308
>UniRef50_Q46TQ0 Cluster: UDP-glucose/GDP-mannose
dehydrogenase:Prephenate dehydrogenase:NADP
oxidoreductase, coenzyme
F420-dependent:6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Ralstonia eutropha JMP134|Rep:
UDP-glucose/GDP-mannose dehydrogenase:Prephenate
dehydrogenase:NADP oxidoreductase, coenzyme
F420-dependent:6-phosphogluconate dehydrogenase,
NAD-binding - Ralstonia eutropha (strain JMP134)
(Alcaligenes eutrophus)
Length = 294
Score = 89.0 bits (211), Expect = 9e-17
Identities = 56/206 (27%), Positives = 97/206 (47%)
Frame = -3
Query: 654 AKKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDF 475
A+ G+L ID+ST+ P + P+ + + + VSG A+ A L + G + +
Sbjct: 81 ARPGALYIDTSTVSPAASAAVAPLLAARDIAYLRVTVSGNNHMAEAAKLTALVSGPADAY 140
Query: 474 ERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLD 295
ER PLL +G QF+ G ++ KL N+L+ +TG AE + +G K GLE + + D
Sbjct: 141 ERIKPLLAALGPAQFYLGDAEQARLMKLVVNLLIALTGGMLAEALTLGSKGGLEWQAMWD 200
Query: 294 VLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPL 115
V+ S+ S P+ + +Y F E M+KD+ L + P+ L
Sbjct: 201 VITASAVAS-------PIVKAKAAQLAVHDYTPTFTVEQMLKDVGLILDAGAQLHVPMGL 253
Query: 114 GAVATQLYRIVQSRGYGQKDFSFVFQ 37
A+ Q+ ++G D++ + +
Sbjct: 254 TALLGQMLHGAAAQGMAGDDYAAIIK 279
>UniRef50_A6G049 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Plesiocystis pacifica SIR-1|Rep: 3-hydroxyisobutyrate
dehydrogenase - Plesiocystis pacifica SIR-1
Length = 307
Score = 89.0 bits (211), Expect = 9e-17
Identities = 60/214 (28%), Positives = 100/214 (46%), Gaps = 1/214 (0%)
Frame = -3
Query: 663 VAHAKKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRK 484
+A +G+L ID T + +Q+ +G F DAP++G +GA+ L M G +
Sbjct: 93 LAGVGQGALVIDCGTTSLKLTEQLAAACEGEGASFLDAPITGSKLGAEGGKLTIMVAGEE 152
Query: 483 EDFERSLPLLKVMGAKQFHCGQ-IGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPK 307
E R++PL ++MG H + +G GQ AK NM + E + + +
Sbjct: 153 EIVARAMPLFEIMGKHTVHVSERLGDGQRAKYCLNMTQAVVLQGLLEGYTLAKLLDVPLT 212
Query: 306 VLLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRS 127
+ ++L NS+ ++ P L+ + +++ F+ +LM KDL LA A R
Sbjct: 213 KMAEILENSAGKTGLGTF--KTPYLL-----AGDFEPHFRLDLMHKDLHLALRHAENERV 265
Query: 126 PIPLGAVATQLYRIVQSRGYGQKDFSFVFQLLKR 25
P+P V LY + G G +DF + LL+R
Sbjct: 266 PLPAATVVRGLYDQAVAEGMGPRDFLAMATLLER 299
>UniRef50_UPI00003C03F8 Cluster: PREDICTED: similar to CG4747-PA;
n=1; Apis mellifera|Rep: PREDICTED: similar to CG4747-PA
- Apis mellifera
Length = 413
Score = 88.6 bits (210), Expect = 1e-16
Identities = 58/202 (28%), Positives = 96/202 (47%), Gaps = 4/202 (1%)
Frame = -3
Query: 633 IDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLL 454
++ + ID + I KG + +A V G AQ TL +A G + F+
Sbjct: 218 VEMTGIDAETSQDIAEAITAKGGRYLEAQVQGSKTQAQEGTLVILAAGDRTLFDECQSCF 277
Query: 453 KVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSA 274
+ MG F+ G++G+ L ++ G+T AE M + + GL+ K +L+VL
Sbjct: 278 EAMGKNSFYLGEVGNASKMNLVLQLMAGVTLAGLAESMALADRAGLQQKDVLEVLE---- 333
Query: 273 RSWSTEVYCPVPGLVPTAPSSRNYDGGFKNEL----MVKDLELASGMALGIRSPIPLGAV 106
T + C P ++ + +GGF +L M KDL L+ GM+ + P+PL A
Sbjct: 334 ---LTSLAC--PAILDKGKAI--IEGGFPTQLPLQHMQKDLRLSLGMSDQLEQPLPLAAA 386
Query: 105 ATQLYRIVQSRGYGQKDFSFVF 40
A ++Y+ + GYG+ D S V+
Sbjct: 387 ANEVYKHAKRLGYGEHDASAVY 408
>UniRef50_Q7WNK6 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Bordetella bronchiseptica|Rep: 3-hydroxyisobutyrate
dehydrogenase - Bordetella bronchiseptica (Alcaligenes
bronchisepticus)
Length = 306
Score = 88.6 bits (210), Expect = 1e-16
Identities = 57/202 (28%), Positives = 94/202 (46%), Gaps = 1/202 (0%)
Frame = -3
Query: 627 SSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKV 448
+ST+ P + + E G G D PVSGG GAQ L +A G+ + + P ++
Sbjct: 99 ASTVAPAYARGLQARLREHGAGLVDGPVSGGATGAQAGALTIIASGQAQALAAAEPAMRA 158
Query: 447 MGAKQFHCG-QIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSAR 271
+ G + G+ KL N +L TAE + +G + G++P VL+ V++ S+
Sbjct: 159 CSSIIHRVGEEAGAASTVKLVNQLLTASHIALTAEALALGARAGVDPDVLVKVISQSAGT 218
Query: 270 SWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVATQLY 91
S E P AP S ++ +KDLE+A A +R P+P+ A A Q++
Sbjct: 219 SRQFEKRAPRMAAGDHAPQS-------TVDIFLKDLEIALDAARALRFPVPIAASAHQVF 271
Query: 90 RIVQSRGYGQKDFSFVFQLLKR 25
+ G G + V ++ +R
Sbjct: 272 SMAAGAGDGPNSDTTVLRVYER 293
>UniRef50_Q1QWQ5 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=4; Proteobacteria|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Chromohalobacter salexigens
(strain DSM 3043 / ATCC BAA-138 / NCIMB13768)
Length = 315
Score = 88.6 bits (210), Expect = 1e-16
Identities = 61/214 (28%), Positives = 101/214 (47%)
Frame = -3
Query: 663 VAHAKKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRK 484
+AH + + S+I + ++ A +G+G+ DAPVSGG GA + TLA M GG
Sbjct: 104 IAHMAPHATLVVMSSIPVDTAQRQAQAAEARGIGYLDAPVSGGERGAIDGTLAIMVGGDP 163
Query: 483 EDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKV 304
FER PL +G + H G GSGQ+AKL N ++ T AE + + + G +P+
Sbjct: 164 ATFERHRPLFAPLG-RAVHVGPAGSGQLAKLANQSIVANTIATVAEALLLAERGGADPRK 222
Query: 303 LLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSP 124
+ + L A S +V+ ++ G + KD + A +A +
Sbjct: 223 VREALMGGFADSTILQVH-------GERMLDEDFRPGGPAKWQWKDTQTAQALADDLALD 275
Query: 123 IPLGAVATQLYRIVQSRGYGQKDFSFVFQLLKRR 22
+P+ + L+ + + G G D S + + L+RR
Sbjct: 276 LPVSRLVDGLFGDLVANGDGDLDHSALIRELRRR 309
>UniRef50_A6VYD9 Cluster: 2-hydroxy-3-oxopropionate reductase
precursor; n=5; Gammaproteobacteria|Rep:
2-hydroxy-3-oxopropionate reductase precursor -
Marinomonas sp. MWYL1
Length = 300
Score = 88.6 bits (210), Expect = 1e-16
Identities = 59/199 (29%), Positives = 96/199 (48%), Gaps = 1/199 (0%)
Frame = -3
Query: 627 SSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKV 448
S+TI K I + L DAPVSGG A + MA G E FE+ P+L
Sbjct: 98 SATISAEDAKAIHQKLSQYQLLMLDAPVSGGAAKAATGDMTVMASGSVEAFEKLQPVLDA 157
Query: 447 MGAKQFHCG-QIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSAR 271
AK ++ G +IG G K+ + +L G+ A AE M + + + ++ DV+ N++
Sbjct: 158 TAAKVYNIGEEIGLGATVKIIHQLLAGVHIAAGAEAMALAARANIPLDLMYDVVTNAAGN 217
Query: 270 SWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVATQLY 91
SW E + +V +Y ++ VKDL L + A ++ P+PL + A ++
Sbjct: 218 SWMFE--NRMKHVV-----DGDYSPKSMVDIFVKDLNLVADTAKELKFPLPLSSTALNMF 270
Query: 90 RIVQSRGYGQKDFSFVFQL 34
+ G+GQ+D S V ++
Sbjct: 271 LSASNAGFGQEDDSAVIKI 289
>UniRef50_A0K0Z6 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding precursor; n=2; Micrococcineae|Rep:
6-phosphogluconate dehydrogenase, NAD-binding precursor
- Arthrobacter sp. (strain FB24)
Length = 301
Score = 88.6 bits (210), Expect = 1e-16
Identities = 64/182 (35%), Positives = 87/182 (47%), Gaps = 3/182 (1%)
Frame = -3
Query: 633 IDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLP-L 457
ID++T +P KQ+ +A +G F DAPVSGG GA + +L+ GG + P L
Sbjct: 90 IDTTTSEPATSKQMAHLADTQGAAFVDAPVSGGRDGAASGSLSAFVGGTDAALAAAEPVL 149
Query: 456 LKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEP-KVLLDVLNNS 280
L + G K H G GSG V KL NN+L ++ E + + G++P K + S
Sbjct: 150 LALTGGKYSHIGGPGSGNVVKLLNNVLAAANLVSVGEALGVAKAYGIDPAKAAASISEAS 209
Query: 279 SARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGI-RSPIPLGAVA 103
S +Y PT S +D GF LM +D LA +A I SP L AVA
Sbjct: 210 GGSRVSANMY-------PTWVLSGTHDSGFSLGLMARDAALAVEVAAQIGESPALLAAVA 262
Query: 102 TQ 97
Q
Sbjct: 263 GQ 264
>UniRef50_Q8TT25 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2;
Methanosarcina|Rep: 3-hydroxyisobutyrate dehydrogenase -
Methanosarcina acetivorans
Length = 300
Score = 88.6 bits (210), Expect = 1e-16
Identities = 59/211 (27%), Positives = 97/211 (45%)
Frame = -3
Query: 654 AKKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDF 475
AKKG L ID STIDP+ + A + GL D PV G A L + GG +E
Sbjct: 93 AKKGCLWIDLSTIDPSSSVKHAEAAKKAGLERLDTPVVGSKDLASKGELIILVGGSQEVL 152
Query: 474 ERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLD 295
+ L +G + G G+G KL N+ +G+ + +E + K+G + K ++
Sbjct: 153 RKHEKFLNKLGKSVIYLGADGNGHKMKLAINLHLGLLAESFSEALVFSQKLGFDAKTFVE 212
Query: 294 VLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPL 115
+NN+ R++ ++ G P N++ F + KDL L + + +P+
Sbjct: 213 TINNTPIRNYISQ------GKGPRIVEG-NFEPAFSLNNLAKDLRLVNEQITKTGAILPM 265
Query: 114 GAVATQLYRIVQSRGYGQKDFSFVFQLLKRR 22
V+ + Y G GQKDFS + ++R+
Sbjct: 266 TKVSIEEYSRTVQNGEGQKDFSVIALEIQRK 296
>UniRef50_UPI0000E49FD0 Cluster: PREDICTED: similar to gamma
hydroxybutyrate dehydrogenase; n=3; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to gamma
hydroxybutyrate dehydrogenase - Strongylocentrotus
purpuratus
Length = 219
Score = 88.2 bits (209), Expect = 2e-16
Identities = 58/206 (28%), Positives = 93/206 (45%)
Frame = -3
Query: 648 KGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFER 469
+G +D ST+D + + F +APV G V A +L +A G KE ++
Sbjct: 19 EGKAFVDMSTVDIGTVTGVSEAVQARDGRFMEAPVCGSVQPAMEGSLIIIAAGDKELYDE 78
Query: 468 SLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVL 289
+ MG K F+ G+ KL NM++G AE M + K GL VLLD+L
Sbjct: 79 CESCFQAMGKKAFYLSDTGNAARMKLVINMIIGGVMCCFAEGMALADKSGLSQSVLLDIL 138
Query: 288 NNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGA 109
N S + P+ A + Y F + KDL+LA M+ + P+P+ +
Sbjct: 139 NLGSIAN-------PLISGKGKAILANKYPPAFPLKYQQKDLKLALAMSEQVDQPLPVAS 191
Query: 108 VATQLYRIVQSRGYGQKDFSFVFQLL 31
+ ++ ++ G G KD S +++ L
Sbjct: 192 AVNEQFKRAKNMGLGDKDTSAIYKSL 217
>UniRef50_O33730 Cluster: Uncharacterized oxidoreductase Sfri_1503;
n=167; Bacteria|Rep: Uncharacterized oxidoreductase
Sfri_1503 - Shewanella frigidimarina (strain NCIMB 400)
Length = 291
Score = 88.2 bits (209), Expect = 2e-16
Identities = 58/209 (27%), Positives = 99/209 (47%)
Frame = -3
Query: 645 GSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERS 466
G++ +D +T +V ++I + F DAPVSGG GA+N L M GG + F+
Sbjct: 89 GAILVDHTTASADVAREIAAYIEPLNIAFLDAPVSGGQAGAENGALTVMMGGDQAHFDTV 148
Query: 465 LPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLN 286
P++ G +G+GQ+ K+ N + + AE ++ GL+ +++V++
Sbjct: 149 KPVISAYSRCAELLGPVGAGQLTKMVNQICIAGVVQGLAEGLHFAKSAGLDGLKVIEVIS 208
Query: 285 NSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAV 106
+A+SW E T + YD GF + M KDL +A A S +P+ A+
Sbjct: 209 KGAAQSWQME------NRYKTMWQGQ-YDFGFAIDWMRKDLGIALDEARRNGSHLPVAAL 261
Query: 105 ATQLYRIVQSRGYGQKDFSFVFQLLKRRK 19
Q Y VQ+ + D S + L++ +
Sbjct: 262 VDQFYSEVQAMKGNRWDTSSLLARLEKSR 290
>UniRef50_A5VBF0 Cluster: 2-hydroxy-3-oxopropionate reductase
precursor; n=1; Sphingomonas wittichii RW1|Rep:
2-hydroxy-3-oxopropionate reductase precursor -
Sphingomonas wittichii RW1
Length = 298
Score = 87.4 bits (207), Expect = 3e-16
Identities = 62/209 (29%), Positives = 98/209 (46%), Gaps = 3/209 (1%)
Frame = -3
Query: 645 GSLXIDSSTIDPNVPKQIFPIALEKG-LGFTDAPVSGGVMGAQNATLAFMAGGRKEDFER 469
G+L +D STI P+ + E G + D PVSGGV GA+ TLA +AGG +R
Sbjct: 89 GALVVDFSTIGPDATRGFAKRLAETGDAQWLDCPVSGGVAGAEAGTLAILAGGDAAAIDR 148
Query: 468 SLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVL 289
PLL ++ A+ G +G+GQ AKL N +++ +A AE M++G +G++ L
Sbjct: 149 VRPLLALLSARVTRMGGVGAGQAAKLCNQLIVATNMLAIAEAMHVGEALGIDLAQLPVAF 208
Query: 288 NNSSARSWSTEVYCP--VPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPL 115
A S +++ P P P P S + M KD+ A + PL
Sbjct: 209 QGGFADSRPLQLFGPRMAPPADPGPPVS-------ELRTMYKDIRSIRAAAAAAEAGTPL 261
Query: 114 GAVATQLYRIVQSRGYGQKDFSFVFQLLK 28
A ++ + G+G +D + +L +
Sbjct: 262 LAGVEAMWTRLIDAGHGGEDVPGLMRLYR 290
>UniRef50_A2C1U6 Cluster: 3-hydroxyisobutyrate dehydrogenase and
related beta-hydroxyacid dehydrogenases; n=2;
Prochlorococcus marinus|Rep: 3-hydroxyisobutyrate
dehydrogenase and related beta-hydroxyacid
dehydrogenases - Prochlorococcus marinus (strain NATL1A)
Length = 287
Score = 87.4 bits (207), Expect = 3e-16
Identities = 60/211 (28%), Positives = 97/211 (45%)
Frame = -3
Query: 651 KKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFE 472
K S ID STI P+ I E+ + + D PVSGG GA N +L+ G ++D
Sbjct: 81 KPNSFVIDFSTISPDKSISIHKRLGEQNIFYVDCPVSGGTEGAHNGSLSLFIGASEKDCL 140
Query: 471 RSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDV 292
+ +V+G + +G GQ K N +L+ T A AE M +G + L ++
Sbjct: 141 SFENIFQVLGKSINYFNGVGKGQQVKALNQILVAGTYAAVAEAMELGKMLELPMDDVVAA 200
Query: 291 LNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLG 112
L +A SW E L+ P GFK EL KDL +A+ +A I +P+
Sbjct: 201 LKVGAANSWPLENRSKAM-LIDKHPL------GFKLELHHKDLSIATELAKSINIDLPIA 253
Query: 111 AVATQLYRIVQSRGYGQKDFSFVFQLLKRRK 19
+ ++ + + G G+ D S + + + ++
Sbjct: 254 SKVKEMEQRLMQTGLGELDVSVLHRYISNKR 284
>UniRef50_O66454 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3;
cellular organisms|Rep: 3-hydroxyisobutyrate
dehydrogenase - Aquifex aeolicus
Length = 288
Score = 87.0 bits (206), Expect = 4e-16
Identities = 57/207 (27%), Positives = 96/207 (46%)
Frame = -3
Query: 648 KGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFER 469
KG ID +T ++ + + G + DAPV G V+ A L + GG KE FE
Sbjct: 87 KGKTVIDMTTNHYLYAQKAYEELKKLGAFYLDAPVLGSVIPALKGELTIVVGGDKEKFEE 146
Query: 468 SLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVL 289
+ PL + ++ G+ G G KL NN+++G AE + +G K G++ + L++VL
Sbjct: 147 NKPLFEKFCRAIYYLGEAGMGSKMKLVNNIVLGGIMEVLAEAIAIGEKAGIDKETLINVL 206
Query: 288 NNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGA 109
N+ + +S+ +V ++ F L+ KDL A + + A
Sbjct: 207 NDGAGKSYILDV-------KKKKLLEEDFSTHFSVNLIYKDLHYAQDLIKDLGLFSFTTA 259
Query: 108 VATQLYRIVQSRGYGQKDFSFVFQLLK 28
+ Y + + G+G DFS V++L K
Sbjct: 260 AVKETYGLARKEGFGNLDFSAVYKLFK 286
>UniRef50_Q9JYH6 Cluster: 3-hydroxyacid dehydrogenase; n=5;
Proteobacteria|Rep: 3-hydroxyacid dehydrogenase -
Neisseria meningitidis serogroup B
Length = 289
Score = 86.2 bits (204), Expect = 6e-16
Identities = 58/202 (28%), Positives = 91/202 (45%)
Frame = -3
Query: 645 GSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERS 466
G + ++ STI P + + G F +APVSG V A N TL + GG +
Sbjct: 89 GKIIVNMSTISPTENLAVKALVEAAGGQFAEAPVSGSVGPATNGTLLILFGGSEAVLNPL 148
Query: 465 LPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLN 286
+ ++G K FH G +G G AKL N L+GI G A +E M M + G++ +++ +
Sbjct: 149 QKIFSLVGKKTFHFGDVGKGSGAKLVLNSLLGIFGEAYSEAMLMARQFGIDTDTIVEAIG 208
Query: 285 NSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAV 106
S+ S P+ + ++R + F + KDL LA + +P
Sbjct: 209 GSAMDS-------PMFQTKKSLWANREFPPAFALKHASKDLNLAVKELEQAGNTLPAVET 261
Query: 105 ATQLYRIVQSRGYGQKDFSFVF 40
YR GYG++D S V+
Sbjct: 262 VAASYRKAVEAGYGEQDVSGVY 283
>UniRef50_A5USN9 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=2; Roseiflexus|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Roseiflexus sp. RS-1
Length = 302
Score = 85.8 bits (203), Expect = 8e-16
Identities = 60/205 (29%), Positives = 95/205 (46%)
Frame = -3
Query: 645 GSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERS 466
G L I+ STI + + + ++G DAPVSG V A+ L + GGR D ER+
Sbjct: 88 GRLFIEMSTIRTSTILSLAGMVDQRGARLLDAPVSGTVAPAREGQLLVLVGGRTSDLERA 147
Query: 465 LPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLN 286
P L V+G + H G G+G KL NM M A AE + +G + GL + +LDV
Sbjct: 148 RPALGVLGRRIIHLGGQGAGTTMKLVLNMTMACFWGALAESLAVGQQFGLNIETMLDVYL 207
Query: 285 NSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAV 106
+S+ + P L+ G + +L+ +A+ G+ P P+ +
Sbjct: 208 DSAVA--PPALRSKTPALLGETSEVAFDVTGVRKDLLAM---VATAQDAGV--PAPVASA 260
Query: 105 ATQLYRIVQSRGYGQKDFSFVFQLL 31
A + + GYG++D + V + L
Sbjct: 261 ALAHFAAATAAGYGERDLAAVVEYL 285
>UniRef50_A1GFG2 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Salinispora arenicola CNS205|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Salinispora arenicola CNS205
Length = 315
Score = 85.4 bits (202), Expect = 1e-15
Identities = 59/206 (28%), Positives = 87/206 (42%)
Frame = -3
Query: 645 GSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERS 466
G+L +D ST+ P +++ ++G F DAPV G A TL F+AGG R
Sbjct: 89 GTLAVDCSTVTPTFSRELAACCAQRGAEFLDAPVLGSRPQADAGTLIFLAGGDLAVLHRI 148
Query: 465 LPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLN 286
P+L+ +G H G G+G KL N L + AE + L P ++ L
Sbjct: 149 EPVLRQVGGAVHHMGPAGTGTQMKLLTNSLFAVQVATVAELIAALHGTDLAPGRAIEALA 208
Query: 285 NSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAV 106
+T V P TA + F EL+ KDLE A+ A R+ +P
Sbjct: 209 -------ATPVTGPAIATAATAMLGDTFPAAFPIELVAKDLEYATADAAARRATVPSTRT 261
Query: 105 ATQLYRIVQSRGYGQKDFSFVFQLLK 28
T YR + G+ + V +L +
Sbjct: 262 TTDTYRRAINHGHRNDHITGVIKLFR 287
>UniRef50_Q0QWD5 Cluster: Putative 3-hydroxyisobutyrate
dehydrogenase; n=1; Leptosphaeria maculans|Rep: Putative
3-hydroxyisobutyrate dehydrogenase - Leptosphaeria
maculans (Blackleg fungus)
Length = 296
Score = 85.4 bits (202), Expect = 1e-15
Identities = 51/147 (34%), Positives = 80/147 (54%), Gaps = 6/147 (4%)
Frame = -3
Query: 462 PLLKVMGA-KQFH-CGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVL 289
P L ++G +FH +G+G AK+ NN L G +ATAE + +G + GL+P+ L V+
Sbjct: 125 PTLHMLGPPSKFHYLSTLGAGLTAKIANNYLSGTILLATAEALALGTRHGLDPRALYAVI 184
Query: 288 NNSSARSWSTEVYCPVPGLVPT--APSSRNYDGGFKNELMVKDLELA--SGMALGIRSPI 121
+S+ +SW + CP+P + PS+ Y GF+ E+MVKDL+L S +G+ +
Sbjct: 185 QSSTGQSWMCDHVCPIPNVQTQYWVPSNSGYRPGFRTEMMVKDLDLGVRSAAEVGVEPTM 244
Query: 120 PLGAVATQLYRIVQSRGYGQKDFSFVF 40
A+A V R G +D S V+
Sbjct: 245 ARAALAVWERAAVDERCRG-RDGSSVY 270
>UniRef50_A6SUL3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=1;
Janthinobacterium sp. Marseille|Rep:
2-hydroxy-3-oxopropionate reductase - Janthinobacterium
sp. (strain Marseille) (Minibacterium massiliensis)
Length = 304
Score = 85.0 bits (201), Expect = 1e-15
Identities = 59/179 (32%), Positives = 89/179 (49%), Gaps = 2/179 (1%)
Frame = -3
Query: 651 KKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFE 472
K G+L ID S+ + +++ +G+ F DAPVSGGV+GA+ +LA MAGG +DF
Sbjct: 89 KHGALVIDMSSTRQSEAQEVHAKLAAQGVRFIDAPVSGGVVGAEAGSLAIMAGGSAQDFA 148
Query: 471 RSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDV 292
+ +L VMG G G GQ+AKL N +++G T AE + + G +P +
Sbjct: 149 EAEAVLTVMGRPTL-VGPAGCGQIAKLCNQLIVGGTLNIVAEALLLAQAGGADPTAVRAA 207
Query: 291 LNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLE--LASGMALGIRSPI 121
+ A S EV+ RN+ G + + KDLE L + G+R P+
Sbjct: 208 IRGGFAESRILEVH-------GQRMLDRNFMPGGQVKSQFKDLENVLIAANNAGLRLPV 259
>UniRef50_Q7WCG3 Cluster: Putative uncharacterized protein; n=2;
Bordetella|Rep: Putative uncharacterized protein -
Bordetella parapertussis
Length = 296
Score = 84.6 bits (200), Expect = 2e-15
Identities = 41/104 (39%), Positives = 60/104 (57%)
Frame = -3
Query: 570 GLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKL 391
G DAPVSGG++GA+ TL M GG D E PL++ MG + FHCG +GS ++AK+
Sbjct: 117 GARLVDAPVSGGIVGAEAGTLTIMMGGETADVEAVRPLMQAMGERLFHCGALGSAEIAKV 176
Query: 390 TNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWST 259
NNML TAE + + G+ + L +L+ S+ ++ T
Sbjct: 177 INNMLCVANMFLTAEAIELAESHGVAFESLTPILSVSTGLNFLT 220
>UniRef50_Q7NEW9 Cluster: Glr3759 protein; n=3; Bacteria|Rep:
Glr3759 protein - Gloeobacter violaceus
Length = 290
Score = 84.6 bits (200), Expect = 2e-15
Identities = 59/203 (29%), Positives = 93/203 (45%)
Frame = -3
Query: 642 SLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERSL 463
++ I+SST+ +++ +G DAPVSG A+ L F+ GG ++
Sbjct: 90 AVAIESSTLSVAGVQELAEHFQARGKTLLDAPVSGSRPQAEAGQLIFLVGGDAGAVAKAG 149
Query: 462 PLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNN 283
P+L MG H G +G+G KL N L+G+ A E + + G++ ++++
Sbjct: 150 PILNAMGGTVHHAGPLGNGAAVKLAINALLGVQVAAMGELIALLRHCGIDEVRAVEIIG- 208
Query: 282 SSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVA 103
ST V P +A + NY F + LM KDL MA R+ PL A
Sbjct: 209 ------STSVCSPAARGAASAMAVGNYAPLFPSALMEKDLGYLQNMAAAHRARAPLTQAA 262
Query: 102 TQLYRIVQSRGYGQKDFSFVFQL 34
++ SRGYG+ + + V QL
Sbjct: 263 RSVFGEAMSRGYGEDNMTGVAQL 285
>UniRef50_Q0FFH2 Cluster: Putative 2-hydroxyacid dehydrogenase; n=2;
Alphaproteobacteria|Rep: Putative 2-hydroxyacid
dehydrogenase - alpha proteobacterium HTCC2255
Length = 303
Score = 84.2 bits (199), Expect = 3e-15
Identities = 51/163 (31%), Positives = 80/163 (49%)
Frame = -3
Query: 645 GSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERS 466
G + +D +T P + +++ ++ G DAPV+G V GA+N + AGG KE ER
Sbjct: 87 GQVWVDLTTNQPELARELAQEIIDTGAIAIDAPVTGAVDGARNGNMTQFAGGDKETIERI 146
Query: 465 LPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLN 286
P++++MG + G GSG + KL +N L I A E + M +K G+E + L
Sbjct: 147 RPVMELMGPVHY-MGSNGSGSITKLASNQLWAIHATAMGEALVMAVKSGVELSRAWEALK 205
Query: 285 NSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLEL 157
++ SW P + + +YD F +L KDL L
Sbjct: 206 IGASESWCMHHDAP-------SVFAGHYDPSFTLDLCQKDLNL 241
>UniRef50_Q9L7S0 Cluster: Uncharacterized oxidoreductase yihU; n=24;
Gammaproteobacteria|Rep: Uncharacterized oxidoreductase
yihU - Salmonella typhimurium
Length = 298
Score = 83.4 bits (197), Expect = 4e-15
Identities = 58/206 (28%), Positives = 95/206 (46%), Gaps = 1/206 (0%)
Frame = -3
Query: 642 SLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERSL 463
+L ID STI P + KG D P+ A TL +AGG E ER+
Sbjct: 89 ALVIDMSTIHPLQTDNLIADMQSKGFSMMDVPIGRTSDNAITGTLLLLAGGTAEQVERAT 148
Query: 462 PLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNN 283
P+L MG + + G G G KL NN + +AE + +GL V L V++
Sbjct: 149 PVLMAMGNELVNTGGPGMGIRVKLINNYMSIALNALSAEAAVLCEALGLSFDVALKVMSG 208
Query: 282 SSA-RSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAV 106
++A + T + P + F +L KDL +A +A + P+PLGA
Sbjct: 209 TAAGKGHFTTTW-------PNKVMKGDLSPAFMIDLAHKDLGIALDVANQLHVPMPLGAA 261
Query: 105 ATQLYRIVQSRGYGQKDFSFVFQLLK 28
+ ++Y + ++ G G++D+S + + ++
Sbjct: 262 SREVYNLARAAGRGREDWSAILEQVR 287
>UniRef50_A6EH53 Cluster: Putative uncharacterized protein; n=1;
Pedobacter sp. BAL39|Rep: Putative uncharacterized
protein - Pedobacter sp. BAL39
Length = 292
Score = 83.0 bits (196), Expect = 6e-15
Identities = 60/205 (29%), Positives = 93/205 (45%)
Frame = -3
Query: 645 GSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERS 466
G + ++ ST+ P + ++ G+ + DAPVSG V A + L M GG ++ F +
Sbjct: 99 GKVIVNMSTVSPAISIKMAAACSAVGIEYLDAPVSGSVKQATDGQLVIMVGGEEQAFHAA 158
Query: 465 LPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLN 286
PLL MG H G G G AKL N L+ I AE + K + + LL +L
Sbjct: 159 EPLLSCMGKLVMHLGASGIGNKAKLAINTLLAIYTEGLAEIVTFSRKHQINTEDLLTLLG 218
Query: 285 NSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAV 106
N + + V+ + G A + NY F + MVKDL LA + PL
Sbjct: 219 NGAL----SNVFTKIKG---DALLNDNYQAAFALKHMVKDLNLAKDEGM----DTPLART 267
Query: 105 ATQLYRIVQSRGYGQKDFSFVFQLL 31
A + ++ + +G++D V + L
Sbjct: 268 ALETFKSA-AAAFGEEDVIAVIKQL 291
>UniRef50_A1ZWM5 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Microscilla marina ATCC 23134|Rep: 3-hydroxyisobutyrate
dehydrogenase - Microscilla marina ATCC 23134
Length = 295
Score = 83.0 bits (196), Expect = 6e-15
Identities = 65/212 (30%), Positives = 96/212 (45%), Gaps = 2/212 (0%)
Frame = -3
Query: 651 KKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFE 472
K +L ID STI P A + + F +APV+G A+NA L F+ GG
Sbjct: 85 KSKALWIDCSTISPAFALASAQEASKHEVVFVEAPVAGTKSHAENAELVFLVGGGTTAIA 144
Query: 471 RSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDV 292
++ P +++MG K H G I K+ N L+ +A AE + +G K GL+ + LL+
Sbjct: 145 QATPYMEMMGKKVVHIGAISKASALKILINYLLAQGMLAFAEALVVGEKQGLDRRFLLEF 204
Query: 291 LNNSSARSWSTEVYCPVPGLVPTAPSSRNYDG--GFKNELMVKDLELASGMALGIRSPIP 118
L N + P L A +D F ELM KD+ L + A
Sbjct: 205 LPNLPVAA---------PFLKSKANKLMQHDAEVQFPLELMYKDITLFADTAEANNITNL 255
Query: 117 LGAVATQLYRIVQSRGYGQKDFSFVFQLLKRR 22
V+ LY+ +G G++DFS V+ L +R
Sbjct: 256 STDVSKNLYQTAIKQGLGREDFSAVYNSLLQR 287
>UniRef50_UPI00015B4B33 Cluster: PREDICTED: similar to
3-hydroxyisobutyrate dehydrogenase; n=1; Nasonia
vitripennis|Rep: PREDICTED: similar to
3-hydroxyisobutyrate dehydrogenase - Nasonia vitripennis
Length = 512
Score = 82.6 bits (195), Expect = 8e-15
Identities = 54/202 (26%), Positives = 95/202 (47%), Gaps = 4/202 (1%)
Frame = -3
Query: 633 IDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLL 454
++ + ID + I KG + +A V G + ++ TL +A G ++ F+
Sbjct: 317 VEMTGIDAETSQDIAEAITAKGARYLEAQVQGSKVQSEEGTLVILAAGDRQLFDDCNSCF 376
Query: 453 KVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSA 274
MG F+ G++G+ L ++ G+T AE M + + GL+ K +L++L
Sbjct: 377 GAMGKNTFYLGEVGNASKMNLVLQLMAGVTLAGLAESMALADRAGLQQKDVLEILE---- 432
Query: 273 RSWSTEVYCPVPGLVPTAPSSRNYDGGFKNEL----MVKDLELASGMALGIRSPIPLGAV 106
T + C P ++ + +GGF +L M KDL L+ M+ + PIPL A
Sbjct: 433 ---LTSLAC--PAILDKGKAI--IEGGFPTQLPLQHMQKDLRLSLSMSDQLEQPIPLAAA 485
Query: 105 ATQLYRIVQSRGYGQKDFSFVF 40
A ++Y+ + GY + D S V+
Sbjct: 486 ANEIYKHAKRLGYAEHDASAVY 507
>UniRef50_UPI0000D55E08 Cluster: PREDICTED: similar to CG4747-PA;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
CG4747-PA - Tribolium castaneum
Length = 267
Score = 82.6 bits (195), Expect = 8e-15
Identities = 56/209 (26%), Positives = 94/209 (44%)
Frame = -3
Query: 654 AKKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDF 475
A G ++ ++IDP+ K I I KG + +A + G A++ +L +A G K F
Sbjct: 64 ALAGKGYVEMTSIDPDTSKDICNIIESKGGRYLEAQMQGSKKQAEDGSLIILAAGDKSLF 123
Query: 474 ERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLD 295
+ K +G F+ G +GS L NM +GI AE M + + GL K L+
Sbjct: 124 DDCQTCFKAIGKTAFYLGTVGSATKMNLCINMALGIGLAGLAESMVLAERCGLSCKDFLE 183
Query: 294 VLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPL 115
+ N S S Y G + S + E M KD++L ++ ++ +P+
Sbjct: 184 IFNLSEGAS----NYLSNKGQLINNRSFSKVEQAL--EYMQKDIKLCLDISNDVKQNLPV 237
Query: 114 GAVATQLYRIVQSRGYGQKDFSFVFQLLK 28
A A + Y+ + GY + D + VF ++
Sbjct: 238 AAAANEAYKTARRSGYDEHDVALVFMKMR 266
>UniRef50_Q9RX16 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=6;
Bacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Deinococcus radiodurans
Length = 310
Score = 82.6 bits (195), Expect = 8e-15
Identities = 59/211 (27%), Positives = 98/211 (46%)
Frame = -3
Query: 657 HAKKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKED 478
H + G++ +D ++ P+ ++ G+ F DAPVSGG GA+ TL M GG ++
Sbjct: 100 HLRPGTVWVDCTSGHPDAARRQRETLDALGVKFLDAPVSGGTSGAEAGTLTVMLGGPADE 159
Query: 477 FERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLL 298
+ + P L G K G+ G+G K NNML+ + A E + + G++ L
Sbjct: 160 IDAASPHLAFAG-KVVRVGETGAGFAVKAVNNMLLAVNLWAAGEGLAALGRSGVDLGAAL 218
Query: 297 DVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIP 118
V+N SS RS ++E L+P +R + F L+ KD +A + ++ P
Sbjct: 219 SVINASSGRSNASE------NLIPQRVLTREFPVTFALGLLAKDTGIALDVVQSAKASAP 272
Query: 117 LGAVATQLYRIVQSRGYGQKDFSFVFQLLKR 25
A L R Q+D + +LL++
Sbjct: 273 TLAQVAGLIRAAAHVVGPQEDHTAALKLLEQ 303
>UniRef50_A0G5G5 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=3; Proteobacteria|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Burkholderia phymatum
STM815
Length = 306
Score = 82.6 bits (195), Expect = 8e-15
Identities = 60/202 (29%), Positives = 95/202 (47%), Gaps = 2/202 (0%)
Frame = -3
Query: 663 VAHAKKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRK 484
+AH + + +D ST + ++ + G+ + DA +SGG A+ L M GG
Sbjct: 81 LAHCRARQIVVDLSTAAASSTIRLARRFTQSGVQYVDAGISGGAAAAEKGALTLMVGGDA 140
Query: 483 EDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKV 304
+ + +K H G+ G+G KL NN L ++ A+AE M G K GL+ +
Sbjct: 141 SAVDALKWAFAPISSKVAHMGESGAGHTTKLLNNFLNAVSLSASAEVMVAGKKAGLDLHL 200
Query: 303 LLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMA--LGIR 130
LLDVLN+SS +++T P +GG +LM KD+ L A LG+
Sbjct: 201 LLDVLNSSSGVNFAT------LNRFPKIVDGDYLEGGLTGKLMTKDVVLYVDRARELGVV 254
Query: 129 SPIPLGAVATQLYRIVQSRGYG 64
S G +A+ + + + GYG
Sbjct: 255 SLNAAGPLAS--FGLGTALGYG 274
>UniRef50_Q5FQ06 Cluster: Putative oxidoreductase; n=1;
Gluconobacter oxydans|Rep: Putative oxidoreductase -
Gluconobacter oxydans (Gluconobacter suboxydans)
Length = 290
Score = 82.2 bits (194), Expect = 1e-14
Identities = 58/199 (29%), Positives = 89/199 (44%)
Frame = -3
Query: 645 GSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERS 466
G L +D+ST+ P+ +A+E G DAP+SG A+ L + GG + +R+
Sbjct: 84 GKLVLDTSTVSPDQADAFASLAVEHGFSLLDAPMSGSTPEAETGDLVMLVGGDEAVVKRA 143
Query: 465 LPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLN 286
P+L V+G H G GS KL N +MG T AE ++ G+ GL+ V+ D L
Sbjct: 144 QPVLDVIGKLTIHAGPAGSAARLKLVVNGVMGATLNVIAEGVSYGLAAGLDRDVVFDTLQ 203
Query: 285 NSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAV 106
V P +R + F LM KD+ L + + +P AV
Sbjct: 204 -------QVAVVSPHHKRKLKMGQNREFPSQFPTRLMSKDMGLLLDAGRKVGAFMPGMAV 256
Query: 105 ATQLYRIVQSRGYGQKDFS 49
A Q + +R + +D+S
Sbjct: 257 ADQALAL-SNRLHANEDYS 274
>UniRef50_Q39MY1 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2;
Burkholderia sp. 383|Rep: 3-hydroxyisobutyrate
dehydrogenase - Burkholderia sp. (strain 383)
(Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 /
R18194))
Length = 303
Score = 82.2 bits (194), Expect = 1e-14
Identities = 57/215 (26%), Positives = 105/215 (48%), Gaps = 1/215 (0%)
Frame = -3
Query: 663 VAHAKKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRK 484
V H L ++ STI ++ ++I ++G+ DAPVSGG A+ TLA + G
Sbjct: 84 VVHGSAVRLYVEMSTIGQDMIERIGEGLAQRGIDIVDAPVSGGPSAARAGTLAMLVSGMP 143
Query: 483 EDFERSLPLLKVMGAKQFHCG-QIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPK 307
E+ PLL+ +G + F G + G Q+ K+ NN++M + AE + MG K GL+
Sbjct: 144 SAVEQVSPLLERIGKEVFPMGDRPGMAQIMKIVNNVVMAANLVVCAEGLAMGAKAGLDAD 203
Query: 306 VLLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRS 127
++ ++++ S +S++ C + + S +D G ++ KD+ L A +
Sbjct: 204 RMMRLIDSGSGQSFA----C---SKIMSRAVSGAFDFGAALAVIEKDMALGLAEARLMDV 256
Query: 126 PIPLGAVATQLYRIVQSRGYGQKDFSFVFQLLKRR 22
+P A ++ G G +DF+ + + ++ R
Sbjct: 257 AMPAIERARDVWHAAYEAGRGGEDFTSILRYVEER 291
>UniRef50_Q7Q161 Cluster: ENSANGP00000013149; n=11; Culicidae|Rep:
ENSANGP00000013149 - Anopheles gambiae str. PEST
Length = 581
Score = 81.8 bits (193), Expect = 1e-14
Identities = 54/204 (26%), Positives = 93/204 (45%), Gaps = 2/204 (0%)
Frame = -3
Query: 645 GSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERS 466
G ++ + +DP I + KG + +A + G A+ TL +A G + FE
Sbjct: 382 GKGYVEMTGVDPETSNDINEAIISKGGRYLEAQIQGSKNQAEEGTLIILASGDRLLFEEC 441
Query: 465 LPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDV-- 292
+ + F+ G +G+ L M+ GIT AE M + + GL+ K +L+V
Sbjct: 442 QSCFEAISRNSFYLGDVGNATKMNLILQMISGITLAGVAEAMALADRAGLQQKDVLEVLE 501
Query: 291 LNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLG 112
L N S+ + + G PT + ++ M KDL+LA +A G+ +P+
Sbjct: 502 LTNMSSEMMLQKGNAIIKGEFPTHHALKH---------MQKDLKLALSLADGLEQSLPIT 552
Query: 111 AVATQLYRIVQSRGYGQKDFSFVF 40
A + ++Y+ + GYG D S V+
Sbjct: 553 AASNEVYKHAKRLGYGSHDASAVY 576
>UniRef50_A7DSF1 Cluster: 2-hydroxy-3-oxopropionate reductase; n=1;
Candidatus Nitrosopumilus maritimus SCM1|Rep:
2-hydroxy-3-oxopropionate reductase - Candidatus
Nitrosopumilus maritimus SCM1
Length = 292
Score = 81.8 bits (193), Expect = 1e-14
Identities = 58/210 (27%), Positives = 97/210 (46%), Gaps = 2/210 (0%)
Frame = -3
Query: 648 KGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFER 469
K + D STIDP+ K I LE G+ D PV GG A L MA G KE FE
Sbjct: 87 KKLIVADMSTIDPSESKNISDKFLEFGIHKLDIPVMGGPNVAITGDLVMMASGNKESFEE 146
Query: 468 SLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVL 289
+ + + K F G+ G KL N+ + + +A +E + + K ++PK+ L++L
Sbjct: 147 CKKVFEKIANKVFFLGEKGVAHSIKLAMNLQITMLALALSEGITLVKKADVDPKIFLEIL 206
Query: 288 NNSSARSWSTE--VYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPL 115
N++ ++ +E + + G YD F E + KD+ + A + +P+
Sbjct: 207 NSTYFKTGMSENKAFKMIDG---------KYDPTFTLENLKKDIITMTNAAKSLGIKLPM 257
Query: 114 GAVATQLYRIVQSRGYGQKDFSFVFQLLKR 25
A ++Y G G D++ + + +KR
Sbjct: 258 IEKAEEVYGNAVKEGLGGIDYTGIIEYIKR 287
>UniRef50_A0LTQ8 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding precursor; n=1; Acidothermus cellulolyticus
11B|Rep: 6-phosphogluconate dehydrogenase, NAD-binding
precursor - Acidothermus cellulolyticus (strain ATCC
43068 / 11B)
Length = 305
Score = 81.4 bits (192), Expect = 2e-14
Identities = 62/206 (30%), Positives = 95/206 (46%), Gaps = 1/206 (0%)
Frame = -3
Query: 663 VAHAKKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRK 484
VA A+ G + + ST++P V + I P KG D PVSG V A+ L M GG
Sbjct: 83 VAGARPGLVVAELSTVEPEVARAIAPELRAKGADILDVPVSGSVAVAREGGLTLMVGGED 142
Query: 483 EDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKV 304
+ P+L ++G + FH G +GSG KL N ++ A AE + + + G+ +
Sbjct: 143 ASLDAIRPVLDIIGRRIFHLGPLGSGAAMKLAVNTVIHGLNAALAEGLVLAERAGIPRSL 202
Query: 303 LLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSP 124
DV +S+A + + P D F+ L+ KDLEL +ALG ++
Sbjct: 203 AYDVFASSAAGA----PFVHYKRQAFEDPEHAPVD--FRLALVRKDLELI--LALGEQTG 254
Query: 123 IPLGAVATQLYRIVQSRGY-GQKDFS 49
PL A L + + + G +D S
Sbjct: 255 TPLPQAAKNLAIVAAALDHVGDRDIS 280
>UniRef50_Q0BTJ3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=1;
Granulibacter bethesdensis CGDNIH1|Rep:
2-hydroxy-3-oxopropionate reductase - Granulobacter
bethesdensis (strain ATCC BAA-1260 / CGDNIH1)
Length = 293
Score = 81.0 bits (191), Expect = 2e-14
Identities = 54/179 (30%), Positives = 84/179 (46%)
Frame = -3
Query: 561 FTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNN 382
+ DAPVSGG GA+N TLA MAGG + R P+ +G + G IG+GQ+AKL N
Sbjct: 114 YVDAPVSGGEGGARNGTLAIMAGGEEAVLNRLAPVFAALG-RMTRIGDIGAGQLAKLANQ 172
Query: 381 MLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNY 202
+++G+T A +E + G P D + A S + N+
Sbjct: 173 LIVGVTIGAVSEAFVLAEAGGASPARFRDAVAGGFADSRILREH-------GQRMLDENF 225
Query: 201 DGGFKNELMVKDLELASGMALGIRSPIPLGAVATQLYRIVQSRGYGQKDFSFVFQLLKR 25
G K+ + +KDL + A + +P+ A LYR + G G D + + + ++R
Sbjct: 226 VPGGKSAIQLKDLRMILQEAKMLGLSLPMTEAAAALYRALCEAGDGDLDHAGLIRQIRR 284
>UniRef50_Q8EW87 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Mycoplasma penetrans|Rep: 3-hydroxyisobutyrate
dehydrogenase - Mycoplasma penetrans
Length = 288
Score = 80.6 bits (190), Expect = 3e-14
Identities = 45/123 (36%), Positives = 68/123 (55%)
Frame = -3
Query: 633 IDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLL 454
ID +T PN Q+ + KG+ DAPV+GG +GA N TL+ M GG E F++ +L
Sbjct: 92 IDFTTSSPNFAVQLANNS--KGIKVLDAPVTGGDIGALNGTLSIMVGGDFETFKKVESIL 149
Query: 453 KVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSA 274
K++G K + G G GQ AKL N +L+ + ATAE +N K ++ + V + +
Sbjct: 150 KILGNKINYFGSAGKGQHAKLFNQILVAVNTFATAEVLNYCKKNNVDIEAAYKVFDKTIG 209
Query: 273 RSW 265
+W
Sbjct: 210 NNW 212
>UniRef50_A3VLN6 Cluster: Oxidoreductase; n=1; Rhodobacterales
bacterium HTCC2654|Rep: Oxidoreductase - Rhodobacterales
bacterium HTCC2654
Length = 293
Score = 80.6 bits (190), Expect = 3e-14
Identities = 43/124 (34%), Positives = 64/124 (51%), Gaps = 1/124 (0%)
Frame = -3
Query: 642 SLXIDSSTIDPNVPKQIFP-IALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERS 466
++ +D ST+ P+ +QI + E G + DAPVSGG+ GA LA GG D R+
Sbjct: 88 AMIVDHSTVPPDATRQIAARVRAEAGAAWVDAPVSGGLAGAAAGQLAIFVGGEDADVTRA 147
Query: 465 LPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLN 286
P+L +G H G GSGQVAK N ++ ++ A AE + + + + P+ L L
Sbjct: 148 WPVLTTLGTTVTHLGPTGSGQVAKACNQVIGFLSFAALAEALALAARYDIAPRDLAVALT 207
Query: 285 NSSA 274
A
Sbjct: 208 GGFA 211
>UniRef50_Q1YHQ4 Cluster: Putative 2-hydroxy-3-oxopropionate
reductase; n=1; Aurantimonas sp. SI85-9A1|Rep: Putative
2-hydroxy-3-oxopropionate reductase - Aurantimonas sp.
SI85-9A1
Length = 292
Score = 79.8 bits (188), Expect = 5e-14
Identities = 58/205 (28%), Positives = 93/205 (45%)
Frame = -3
Query: 645 GSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERS 466
G +D ST + V Q+ G F DAPVSGG A+ TLA M GG ++ E +
Sbjct: 89 GRTVVDFSTTEMAVTHQVAAAIEAVGGRFVDAPVSGGPGAAETGTLAIMFGGSEQAAEAA 148
Query: 465 LPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLN 286
P+L+ +G + H G IG+GQ KL N +L AE + + G++ + L
Sbjct: 149 RPMLEQLG-RATHMGAIGTGQATKLVNQVLCLTNYCVAAEALRLAQAYGVDAAKIPHALE 207
Query: 285 NSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAV 106
S + P AP G+ +++ KD E+ +P+ A
Sbjct: 208 PGLGNSAVLQAIYPRMVEEDFAPR------GYARQIL-KDFEMLHSATKAQHLALPMSAQ 260
Query: 105 ATQLYRIVQSRGYGQKDFSFVFQLL 31
A ++R++ ++G G+ D + V +LL
Sbjct: 261 AMTMFRMLVAQGDGELDGAAVVKLL 285
>UniRef50_A0QZR7 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Mycobacterium smegmatis str. MC2 155|Rep:
3-hydroxyisobutyrate dehydrogenase - Mycobacterium
smegmatis (strain ATCC 700084 / mc(2)155)
Length = 299
Score = 79.8 bits (188), Expect = 5e-14
Identities = 58/208 (27%), Positives = 92/208 (44%), Gaps = 1/208 (0%)
Frame = -3
Query: 642 SLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERSL 463
++ ++ ST+ + G G DAPVSGG GA+ +L MA G E+
Sbjct: 89 TVVVNLSTVGRQALTEAADALTHAGYGCLDAPVSGGAEGARTGSLTIMASGDPTTIEQCS 148
Query: 462 PLLKVMGAKQFHCG-QIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLN 286
+ V+ K G Q G Q K+ NN+L +ATAE + K G+ L+ LN
Sbjct: 149 SVFDVIAGKVIVVGNQPGQAQAIKVANNVLSLGALVATAEATAITRKAGIPLDTALEALN 208
Query: 285 NSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAV 106
SS R+ +T V P L + +D GF +KD+ L +A + PL +
Sbjct: 209 ASSGRNTATAVKFPRHVL------TGRFDFGFPTSGALKDVSLFLELAAELGVEAPLSSA 262
Query: 105 ATQLYRIVQSRGYGQKDFSFVFQLLKRR 22
++ +G+GQ+D + + + R
Sbjct: 263 VQAIWHTAAEQGFGQQDCTRIVSFYEAR 290
>UniRef50_A6VLT0 Cluster: 2-hydroxy-3-oxopropionate reductase; n=2;
Pasteurellaceae|Rep: 2-hydroxy-3-oxopropionate reductase
- Actinobacillus succinogenes 130Z
Length = 289
Score = 79.4 bits (187), Expect = 7e-14
Identities = 54/213 (25%), Positives = 92/213 (43%)
Frame = -3
Query: 663 VAHAKKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRK 484
V A KG L ++ ST+ P +Q+ + + G F +APVSG A+ L +A G++
Sbjct: 84 VLTALKGKLVVNMSTVSPTQNQQLEFLLAKHGAEFIEAPVSGSSKVAEAGKLLVLAAGKE 143
Query: 483 EDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKV 304
E E+ PL + F+ G++G KL N L+GI A E + + G+
Sbjct: 144 EIVEQLKPLFAAFSTQTFYYGEVGKAGGVKLMINSLLGIFIQAYGEALLFAEQFGIPKDQ 203
Query: 303 LLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSP 124
++++++ S S + P+ ++ F + M KD LA +
Sbjct: 204 VIEMISGSFMNSQIFQAKVPM-------YRQNDFSPAFMMKHMTKDFNLAKSEIAKMGKA 256
Query: 123 IPLGAVATQLYRIVQSRGYGQKDFSFVFQLLKR 25
PL AT Y G + D + ++Q L +
Sbjct: 257 FPLIQQATVSYNQANQSGLSEVDMAAIYQYLAK 289
>UniRef50_A0QUD5 Cluster: 3-hydroxyisobutyrate dehydrogenase family
protein; n=1; Mycobacterium smegmatis str. MC2 155|Rep:
3-hydroxyisobutyrate dehydrogenase family protein -
Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
Length = 326
Score = 79.4 bits (187), Expect = 7e-14
Identities = 55/211 (26%), Positives = 97/211 (45%)
Frame = -3
Query: 663 VAHAKKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRK 484
VA+A+ G++ +D STI P++ ++ G+ F APV+GG ++ LA G +
Sbjct: 90 VANARAGAVLVDCSTISPDMSARVRARCDRAGVHFLAAPVAGGPPVIESGGLAMAVSGDR 149
Query: 483 EDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKV 304
+ FE + +L+V+ + G + ++ K+ +N+L+ T E + G +
Sbjct: 150 QAFEHAADVLRVVAPNLIYVGPGDTSRLVKICHNLLVAATLEVLGELCVLAESHGASRQA 209
Query: 303 LLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSP 124
LL L +++ S E P+ S ++ F + LM KDLEL G+A
Sbjct: 210 LLSFLRSTAISSRFIEYKAPL-------LESLDFTPAFTSSLMQKDLELGLGLAGQADVT 262
Query: 123 IPLGAVATQLYRIVQSRGYGQKDFSFVFQLL 31
+P+ A YR G + D + V+ L
Sbjct: 263 MPVTAQVHATYRAANESGLAELDAAAVYLYL 293
>UniRef50_Q1EPJ1 Cluster: 6-phosphogluconate dehydrogenase
NAD-binding domain-containing protein; n=8;
Magnoliophyta|Rep: 6-phosphogluconate dehydrogenase
NAD-binding domain-containing protein - Musa acuminata
(Banana)
Length = 314
Score = 79.4 bits (187), Expect = 7e-14
Identities = 63/218 (28%), Positives = 103/218 (47%), Gaps = 7/218 (3%)
Frame = -3
Query: 645 GSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERS 466
G + +D ++ DP + +++ A +G DAPVSGG +GA++ TLA +AGG +
Sbjct: 103 GGVLVDCTSSDPALAREVAAAARARGCWAVDAPVSGGDVGARDGTLAILAGGDEGVVHWL 162
Query: 465 LPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLN 286
PL + +G + G GSGQ +K+ N + +G T + +E + + GL+ LD +
Sbjct: 163 SPLFEALGRATW-MGPAGSGQSSKIANQITIGGTILGLSEAIVFAGRAGLDVPRFLDAVR 221
Query: 285 NSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDL-------ELASGMALGIRS 127
+A S + E++ AP GGF E MVKDL E G
Sbjct: 222 GGAAGSRAMEIFGERMARRDFAP------GGFA-EYMVKDLGMGLRGGEDGGEEETGKGV 274
Query: 126 PIPLGAVATQLYRIVQSRGYGQKDFSFVFQLLKRRKQK 13
+P A+ QLY + + G G+ + +++R K
Sbjct: 275 VLPGAALCQQLYLAMVANGDGKMGGQGLITVIERLNGK 312
>UniRef50_Q9LM23 Cluster: Fructose-bisphosphate aldolase; n=2;
Arabidopsis thaliana|Rep: Fructose-bisphosphate aldolase
- Arabidopsis thaliana (Mouse-ear cress)
Length = 1486
Score = 79.0 bits (186), Expect = 1e-13
Identities = 58/200 (29%), Positives = 94/200 (47%), Gaps = 3/200 (1%)
Frame = -3
Query: 645 GSLXIDSSTIDPNVPKQIFPIALEKG--LGFTDAPVSGGVMGAQNATLAFMAGGRKEDFE 472
G+ + +ST+ P Q+ +G L DAPVSGGV A L MA G E +
Sbjct: 441 GATVVLASTVSPAFVSQLERRLENEGKDLKLVDAPVSGGVKRAAMGELTIMASGTDEALK 500
Query: 471 RSLPLLKVMGAKQFHC-GQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLD 295
+ +L + K + G G+G K+ N +L G+ + AE M G ++GL + L +
Sbjct: 501 SAGLVLSALSEKLYVIKGGCGAGSGVKMVNQLLAGVHIASAAEAMAFGARLGLNTRKLFN 560
Query: 294 VLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPL 115
V++NS SW E VP ++ +Y ++ VKDL + + + P+ +
Sbjct: 561 VISNSGGTSWMFE--NRVPHML-----DNDYTPYSALDIFVKDLGIVTREGSSRKVPLHI 613
Query: 114 GAVATQLYRIVQSRGYGQKD 55
VA QL+ + G+G+ D
Sbjct: 614 STVAHQLFLAGSAAGWGRID 633
Score = 66.9 bits (156), Expect = 4e-10
Identities = 44/154 (28%), Positives = 80/154 (51%), Gaps = 1/154 (0%)
Frame = -3
Query: 555 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHC-GQIGSGQVAKLTNNM 379
DA V G+ + L +A GR + R+ P L M + G+IG+G K+ N +
Sbjct: 145 DAYVLKGMSELLDGKLMIIASGRSDSITRAQPYLTAMCQNLYTFEGEIGAGSKVKMVNEL 204
Query: 378 LMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYD 199
L GI +A E +++G + G+ P +L D+++N++ SW + + P+ L+ + +
Sbjct: 205 LEGIHLVAAVEAISLGSQAGVHPWILYDIISNAAGNSWIYKNHIPL--LL-----KDDIE 257
Query: 198 GGFKNELMVKDLELASGMALGIRSPIPLGAVATQ 97
G F +++ ++L + A + P+PL AVA Q
Sbjct: 258 GRFL-DVLSQNLAIVEDKAKSLPFPVPLLAVARQ 290
>UniRef50_Q8VYC5 Cluster: Fructose-bisphosphate aldolase; n=12;
cellular organisms|Rep: Fructose-bisphosphate aldolase -
Arabidopsis thaliana (Mouse-ear cress)
Length = 1373
Score = 79.0 bits (186), Expect = 1e-13
Identities = 58/200 (29%), Positives = 94/200 (47%), Gaps = 3/200 (1%)
Frame = -3
Query: 645 GSLXIDSSTIDPNVPKQIFPIALEKG--LGFTDAPVSGGVMGAQNATLAFMAGGRKEDFE 472
G+ + +ST+ P Q+ +G L DAPVSGGV A L MA G E +
Sbjct: 408 GATVVLASTVSPAFVSQLERRLENEGKDLKLVDAPVSGGVKRAAMGELTIMASGTDEALK 467
Query: 471 RSLPLLKVMGAKQFHC-GQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLD 295
+ +L + K + G G+G K+ N +L G+ + AE M G ++GL + L +
Sbjct: 468 SAGLVLSALSEKLYVIKGGCGAGSGVKMVNQLLAGVHIASAAEAMAFGARLGLNTRKLFN 527
Query: 294 VLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPL 115
V++NS SW E VP ++ +Y ++ VKDL + + + P+ +
Sbjct: 528 VISNSGGTSWMFE--NRVPHML-----DNDYTPYSALDIFVKDLGIVTREGSSRKVPLHI 580
Query: 114 GAVATQLYRIVQSRGYGQKD 55
VA QL+ + G+G+ D
Sbjct: 581 STVAHQLFLAGSAAGWGRID 600
Score = 66.9 bits (156), Expect = 4e-10
Identities = 44/154 (28%), Positives = 80/154 (51%), Gaps = 1/154 (0%)
Frame = -3
Query: 555 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHC-GQIGSGQVAKLTNNM 379
DA V G+ + L +A GR + R+ P L M + G+IG+G K+ N +
Sbjct: 121 DAYVLKGMSELLDGKLMIIASGRSDSITRAQPYLTAMCQNLYTFEGEIGAGSKVKMVNEL 180
Query: 378 LMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYD 199
L GI +A E +++G + G+ P +L D+++N++ SW + + P+ L+ + +
Sbjct: 181 LEGIHLVAAVEAISLGSQAGVHPWILYDIISNAAGNSWIYKNHIPL--LL-----KDDIE 233
Query: 198 GGFKNELMVKDLELASGMALGIRSPIPLGAVATQ 97
G F +++ ++L + A + P+PL AVA Q
Sbjct: 234 GRFL-DVLSQNLAIVEDKAKSLPFPVPLLAVARQ 266
>UniRef50_Q49A26 Cluster: Cytokine-like nuclear factor n-pac; n=46;
Euteleostomi|Rep: Cytokine-like nuclear factor n-pac -
Homo sapiens (Human)
Length = 553
Score = 79.0 bits (186), Expect = 1e-13
Identities = 50/205 (24%), Positives = 90/205 (43%)
Frame = -3
Query: 651 KKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFE 472
+ G +D ST+D + ++ + + +G F +APVSG + + L +A G + +E
Sbjct: 352 RPGKCYVDMSTVDADTVTELAQVIVSRGGRFLEAPVSGNQQLSNDGMLVILAAGDRGLYE 411
Query: 471 RSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDV 292
+ MG F G++G+ L NM+ G AE + + G + LLD+
Sbjct: 412 DCSSCFQTMGKTSFFLGEVGNAAKMMLIVNMVQGSFMATIAEGLTLAQVTGRSQQTLLDI 471
Query: 291 LNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLG 112
LN S + C ++ N+ F + + KDL LA + + P P+
Sbjct: 472 LNQGQLASIFLDQKC--QNIL-----QGNFKPDFYLKYIQKDLRLAIALGDAVNHPTPMA 524
Query: 111 AVATQLYRIVQSRGYGQKDFSFVFQ 37
A A ++Y+ ++ D S V++
Sbjct: 525 AAANEVYKRAKALDQSDNDMSAVYR 549
>UniRef50_A3JU55 Cluster: Predicted dehydrogenase, with
NAD(P)-binding Rossmann-fold domain; n=2; Bacteria|Rep:
Predicted dehydrogenase, with NAD(P)-binding
Rossmann-fold domain - Rhodobacterales bacterium
HTCC2150
Length = 302
Score = 78.6 bits (185), Expect = 1e-13
Identities = 58/199 (29%), Positives = 90/199 (45%), Gaps = 2/199 (1%)
Frame = -3
Query: 663 VAHAKKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRK 484
+AH KG I S+TI P ++I + G+ D PVSGG GAQ TL MA G
Sbjct: 81 LAHMPKGGAVILSATIKPVEAEEIGAAMADSGIHLIDTPVSGGFPGAQGGTLTMMAAGVD 140
Query: 483 EDFERSLPLLKVMGAKQFHCG-QIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPK 307
E + P+++ + A + G + G GQ K L+G AT E + K G+ +
Sbjct: 141 EVLDTYAPVMEAVSATIWCVGTEAGQGQTVKACLQSLLGAMFSATFEASVLAAKAGINGE 200
Query: 306 VLLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDG-GFKNELMVKDLELASGMALGIR 130
V +V+ NSS C + R ++G G M KDL ++ G+ +
Sbjct: 201 VFHNVVANSSGG-------CGITAGSLEKIIDRQFEGTGSHIATMHKDLTISMGLGEQLG 253
Query: 129 SPIPLGAVATQLYRIVQSR 73
P+ + A Q++ ++R
Sbjct: 254 VPLHTASAAMQIFHAGKTR 272
>UniRef50_A1WJN2 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=3; Proteobacteria|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Verminephrobacter eiseniae
(strain EF01-2)
Length = 297
Score = 78.6 bits (185), Expect = 1e-13
Identities = 59/213 (27%), Positives = 97/213 (45%)
Frame = -3
Query: 663 VAHAKKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRK 484
+A A+ G + +D T + +Q+ + F DAPV+ AQ TLA M G
Sbjct: 88 LASARPGHIVVDLGTSSVDGTRQLAAEFAARQAKFADAPVARTRAAAQAGTLAVMVGADP 147
Query: 483 EDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKV 304
E F PL+ + CG +G GQV K+ NNM++ T +A +E +G K G++ V
Sbjct: 148 ELFGVIEPLIATFASDIALCGPVGCGQVLKILNNMILFETVVAISEAKAIGEKAGVDASV 207
Query: 303 LLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSP 124
L D L N SA S++ + + ++P R + + + + L+LA + RS
Sbjct: 208 LFDTLANGSADSFALRNH-GMKAVLPGEFPERAFSVHYARKDLQYALQLADDTGVDARS- 265
Query: 123 IPLGAVATQLYRIVQSRGYGQKDFSFVFQLLKR 25
V + + G G+K + +L+ R
Sbjct: 266 ---ARVVDRWFAQAIEAGLGEKYHPVISRLIAR 295
>UniRef50_Q89RT2 Cluster: Bll2680 protein; n=1; Bradyrhizobium
japonicum|Rep: Bll2680 protein - Bradyrhizobium
japonicum
Length = 300
Score = 77.8 bits (183), Expect = 2e-13
Identities = 53/214 (24%), Positives = 99/214 (46%), Gaps = 1/214 (0%)
Frame = -3
Query: 663 VAHAKKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRK 484
+A G++ I++ST+ ++ A +G+ + APVSG L G K
Sbjct: 86 IAAMAPGAVLIETSTVSVEASTEVAASAQARGVLYLRAPVSGNASIVHTGALTCFVSGPK 145
Query: 483 EDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKV 304
+ F+ + PL + + G + AKL N+++ ++ AE + + K G+ +
Sbjct: 146 DAFDNAKPLFAAFTRARTYLGPAEEARYAKLAVNLMIAVSAAMMAESLALARKGGIAWQD 205
Query: 303 LLDVLNNSSARSWSTEVYCPVPGLVPTAP-SSRNYDGGFKNELMVKDLELASGMALGIRS 127
+L VL++S+ S + TAP +R+++ F + M KDL+L G +
Sbjct: 206 ILKVLDDSAVASPMVK--------YKTAPLRTRDFESTFSCKQMAKDLDLILGAGHAVGV 257
Query: 126 PIPLGAVATQLYRIVQSRGYGQKDFSFVFQLLKR 25
P+ L A + Y + ++G G+ DF + L+R
Sbjct: 258 PLQLAAQVRETYGSLVAQGDGEADFIATVKHLER 291
>UniRef50_A0R1N4 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=3; Mycobacterium|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Mycobacterium smegmatis
(strain ATCC 700084 / mc(2)155)
Length = 272
Score = 77.8 bits (183), Expect = 2e-13
Identities = 42/126 (33%), Positives = 62/126 (49%)
Frame = -3
Query: 645 GSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERS 466
G + ST+ P+ +I EKG+ DAPVSGG A+ TL MAGG ++ ++
Sbjct: 87 GGIIAIHSTVHPDTCTEIAEQVAEKGISLIDAPVSGGEPAAKAGTLLVMAGGDEDIVDKV 146
Query: 465 LPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLN 286
P+ G +GSGQVAK+ NN+L A + +G +G+ L +V+
Sbjct: 147 RPVFATYADPVVRLGGVGSGQVAKILNNLLFSANLGAAMSALELGEALGVPRSALCEVIT 206
Query: 285 NSSARS 268
SA S
Sbjct: 207 RGSANS 212
>UniRef50_Q0KC92 Cluster: 3-Hydroxyisobutyrate dehydrogenase; n=1;
Ralstonia eutropha H16|Rep: 3-Hydroxyisobutyrate
dehydrogenase - Ralstonia eutropha (strain ATCC 17699 /
H16 / DSM 428 / Stanier 337)(Cupriavidus necator (strain
ATCC 17699 / H16 / DSM 428 / Stanier337))
Length = 305
Score = 77.4 bits (182), Expect = 3e-13
Identities = 53/209 (25%), Positives = 94/209 (44%)
Frame = -3
Query: 654 AKKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDF 475
A + +D ST+ P+ ++ +G F APVSG V A +A L+ G + F
Sbjct: 96 ATADKVFVDMSTVSPDASAEVAAALARRGAAFLRAPVSGTVSLAASAQLSCFVSGPRPAF 155
Query: 474 ERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLD 295
+ P+L + A+Q + G +V KL NM++ ++ E + G + GL +++D
Sbjct: 156 DAVQPVLACLTARQSYVGGADEARVIKLMINMMVFMSTAVIGEGLAFGARAGLNRALMVD 215
Query: 294 VLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPL 115
+N+S S R+Y L+VKDL+LA +A +P+
Sbjct: 216 AINDSIVGSAHYRTKA-------EQLKQRDYAAVGPISLVVKDLDLALAVARDNAVALPM 268
Query: 114 GAVATQLYRIVQSRGYGQKDFSFVFQLLK 28
++ Q ++Q R G D + + +L+
Sbjct: 269 SSLVRQYLALMQQRRQGHLDIAALADVLE 297
>UniRef50_A5VEA3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=1;
Sphingomonas wittichii RW1|Rep:
2-hydroxy-3-oxopropionate reductase - Sphingomonas
wittichii RW1
Length = 264
Score = 77.0 bits (181), Expect = 4e-13
Identities = 40/138 (28%), Positives = 70/138 (50%)
Frame = -3
Query: 663 VAHAKKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRK 484
+A A+ G + + S++ + + ++G+ DAPVSGG GA+ T++FM GG +
Sbjct: 81 LASARPGLIVVLHSSVSTDTIAEAAKATRDRGVVLVDAPVSGGAQGARARTMSFMVGGEE 140
Query: 483 EDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKV 304
+R PL ++ G G G+ +AKL + + + MA AE + +G GL ++
Sbjct: 141 AALDRCQPLFELSGPNILRTGPAGTATLAKLAHQVAIIGNIMAMAEAVRLGTAGGLSAEM 200
Query: 303 LLDVLNNSSARSWSTEVY 250
+ + ARSW E +
Sbjct: 201 VKQAVAGGLARSWIAETW 218
>UniRef50_A1UJF2 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=6; Actinomycetales|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Mycobacterium sp. (strain KMS)
Length = 272
Score = 77.0 bits (181), Expect = 4e-13
Identities = 40/126 (31%), Positives = 62/126 (49%)
Frame = -3
Query: 645 GSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERS 466
G++ ST+ P+ ++I A + + DAPVSGG + L M GG + D E++
Sbjct: 87 GAMIAIHSTVHPDTCREIAEKAAAQNVSVIDAPVSGGAPAVEQGKLLVMVGGEEADVEKA 146
Query: 465 LPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLN 286
P+ H G +GSGQV K+ NN+L + + +G +G+ L +VLN
Sbjct: 147 RPVFATYADPIVHLGPLGSGQVTKILNNLLFTANLGSALSTLELGESLGIPRTQLAEVLN 206
Query: 285 NSSARS 268
SA S
Sbjct: 207 GGSATS 212
>UniRef50_Q8F4I7 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=4;
Leptospira|Rep: 3-hydroxyisobutyrate dehydrogenase -
Leptospira interrogans
Length = 296
Score = 75.8 bits (178), Expect = 9e-13
Identities = 52/199 (26%), Positives = 91/199 (45%)
Frame = -3
Query: 648 KGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFER 469
K + ID T ++ ++ + EK + F D+P++G A++ + FM G ++ D +
Sbjct: 87 KPPILIDCGTTSLSLTLKLSKLCSEKKIRFYDSPMTGSKNAARDGQILFMIGAKQVDIKD 146
Query: 468 SLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVL 289
+V G +CG IG GQ AKL NM+ E + L+P +L ++L
Sbjct: 147 IQFFFEVCGKNAVYCGSIGGGQKAKLALNMIQAGIFQVYMEGFELAKNSELDPSILKEIL 206
Query: 288 NNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGA 109
S+A+S E P S +Y+ F + M KD+ A +A ++ + L
Sbjct: 207 LQSAAKSGIAEFKFPY-------VFSGDYETHFSLKNMRKDVYHAIELAKENKTNLSLCK 259
Query: 108 VATQLYRIVQSRGYGQKDF 52
++Y + + GY + DF
Sbjct: 260 NLPEIYDLGMNAGYAENDF 278
>UniRef50_A3ET09 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3;
Bacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Leptospirillum sp. Group II UBA
Length = 311
Score = 75.8 bits (178), Expect = 9e-13
Identities = 55/210 (26%), Positives = 97/210 (46%)
Frame = -3
Query: 645 GSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERS 466
G + ++ +T+ P++ ++ + ++G +A ++ + A+ TL M GG+KE FER
Sbjct: 97 GRVFVNCATLSPDIHVEVERRSNDRGADCLEASMASSITQAREGTLYLMVGGKKEAFERV 156
Query: 465 LPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLN 286
P+L+ M A G G K NM+M I AE + + +GL+ ++ +V +
Sbjct: 157 RPVLEAMSASLRWIGPAGQAAKIKALVNMVMNINTAGLAEGLGLADALGLDLAMVREVFS 216
Query: 285 NSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAV 106
+ A S E G +R +D F KD +A +A + +PL
Sbjct: 217 QTGAASRVLE----TDG---ADMQNREHDVYFSAAHAAKDSRIALALAARVGLNLPLAKA 269
Query: 105 ATQLYRIVQSRGYGQKDFSFVFQLLKRRKQ 16
A+ Y + S G G+ D S V +L R ++
Sbjct: 270 ASGQYDRMVSLGLGEIDKSGVSELTFRARR 299
>UniRef50_A0GPK7 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=4; Burkholderia|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Burkholderia phytofirmans
PsJN
Length = 297
Score = 75.8 bits (178), Expect = 9e-13
Identities = 60/203 (29%), Positives = 92/203 (45%), Gaps = 1/203 (0%)
Frame = -3
Query: 654 AKKGSLXIDSSTIDPNVPKQIFPIALEK-GLGFTDAPVSGGVMGAQNATLAFMAGGRKED 478
A++G+ +D ST+ P+ + E+ G + DAPVSGG GA TLA MAGG
Sbjct: 89 ARRGATLVDHSTLAPSQTRAFARRWREQTGGDWIDAPVSGGTSGAAAGTLAIMAGGDATL 148
Query: 477 FERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLL 298
E P+L+ A+ G G+GQ KL N ++ T A AE + G++ +
Sbjct: 149 IETLTPILRGYAARVTRMGGSGAGQATKLANQTIVMTTIAALAEATRLARHAGIDTARIP 208
Query: 297 DVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIP 118
L A S + P +VP A +S G + M+KDL+ +A + +P
Sbjct: 209 AALAGGWADSVLLQTLMP-RMIVPPAQAS----GTIRT--MLKDLDAVESLARESDTTLP 261
Query: 117 LGAVATQLYRIVQSRGYGQKDFS 49
+ A+ + +G G D S
Sbjct: 262 VAALVRRWLTQAVEQGLGDADIS 284
>UniRef50_A7I8V1 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Candidatus Methanoregula boonei
6A8|Rep: 6-phosphogluconate dehydrogenase, NAD-binding -
Methanoregula boonei (strain 6A8)
Length = 288
Score = 75.8 bits (178), Expect = 9e-13
Identities = 45/206 (21%), Positives = 96/206 (46%)
Frame = -3
Query: 645 GSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERS 466
G + ID++T + A + G + + PV G V+ A L + G + +E
Sbjct: 88 GKIIIDTTTNHFGRVSDFYAGARDHGATYLECPVLGSVVPASQGKLTVLVSGDEGTYEVV 147
Query: 465 LPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLN 286
PLL +G+ ++ G+ KL NN+++G AE + +G G++ ++D+L
Sbjct: 148 KPLLSRIGSTLYYLGEPALATKMKLINNLVLGSFMATCAEAVALGEAAGIDRGEVIDILL 207
Query: 285 NSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAV 106
+ + S V +R + F + L+ KDL + ++ P+ +G+
Sbjct: 208 SGAGNSM-------VLAAKKDKLKNREFSPHFSSALIYKDLHYLQDLCRTLKKPLFVGST 260
Query: 105 ATQLYRIVQSRGYGQKDFSFVFQLLK 28
+++ + +S+G ++DFS ++++ +
Sbjct: 261 VKEVFALARSKGIDEQDFSVLYEVFR 286
>UniRef50_Q3W3N3 Cluster: Putative uncharacterized protein; n=1;
Frankia sp. EAN1pec|Rep: Putative uncharacterized
protein - Frankia sp. EAN1pec
Length = 315
Score = 75.4 bits (177), Expect = 1e-12
Identities = 50/165 (30%), Positives = 72/165 (43%)
Frame = -3
Query: 651 KKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFE 472
+ GSL + ST P + A +G+ DAPVS G L +AGG + D +
Sbjct: 98 RSGSLVVIHSTCSPRTCVDLAARARGRGITVLDAPVSNGAPDESGRQLVVLAGGDRRDVD 157
Query: 471 RSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDV 292
R P+ ++ G + G +GS Q+ KL NN L + A E + +GL+P +
Sbjct: 158 RCAPVFELFGRTVVYTGDVGSAQLTKLVNNALFIVHRSAAIEALRAAGTLGLDPDGVRVA 217
Query: 291 LNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLEL 157
L SA + S P+PG P F L+ KDL L
Sbjct: 218 LQECSANARS----LPIPGGPPIGGHGGPPPDAFV-ALLTKDLNL 257
>UniRef50_Q4Q9Z1 Cluster: Dehydrogenase-like protein; n=6;
Trypanosomatidae|Rep: Dehydrogenase-like protein -
Leishmania major
Length = 431
Score = 74.9 bits (176), Expect = 2e-12
Identities = 49/170 (28%), Positives = 78/170 (45%), Gaps = 1/170 (0%)
Frame = -3
Query: 663 VAHAKKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRK 484
V +A+ G + +D +T+D + ++ A +G F DAP+SG A N L M GG
Sbjct: 100 VTNARPGQIIVDHTTVDMELSRECAHEAERRGAVFLDAPMSGSPKQAFNNQLVLMVGGPA 159
Query: 483 EDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEP-K 307
E +R P+ ++ H G GSG AKL + L+ A AE M + ++G+E +
Sbjct: 160 EQVQRVSPIFRMYADHIHHMGANGSGTAAKLLSQALVASHNAAAAEAMTIANRLGIEDYQ 219
Query: 306 VLLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLEL 157
L+ VL+ S S P + P G + +++DL L
Sbjct: 220 KLIQVLDASWGSSTMLRRNAPTMQDLVRNPDKLAPSSGASIDNLLEDLAL 269
>UniRef50_Q2CHC8 Cluster: Oxidoreductase; n=1; Oceanicola granulosus
HTCC2516|Rep: Oxidoreductase - Oceanicola granulosus
HTCC2516
Length = 288
Score = 74.5 bits (175), Expect = 2e-12
Identities = 41/132 (31%), Positives = 65/132 (49%)
Frame = -3
Query: 663 VAHAKKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRK 484
+A A + +D ST+ P + I A + DAPVSGG A+ L + GG++
Sbjct: 80 LAGAGGAEIVVDCSTVPPEATRDI---AGRMDAAWIDAPVSGGPQLAETGELTMLLGGQE 136
Query: 483 EDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKV 304
D ER+ ++ + A H G +G+GQ AK N ++G+ + AE + + K G++P
Sbjct: 137 RDIERARAVIDALAANATHLGPLGAGQAAKTLNQAIVGVNYVLMAELLALARKSGIDPAR 196
Query: 303 LLDVLNNSSARS 268
L L A S
Sbjct: 197 LPQALAGGMADS 208
>UniRef50_Q12H32 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding precursor; n=1; Polaromonas sp. JS666|Rep:
6-phosphogluconate dehydrogenase, NAD-binding precursor
- Polaromonas sp. (strain JS666 / ATCC BAA-500)
Length = 297
Score = 74.5 bits (175), Expect = 2e-12
Identities = 57/205 (27%), Positives = 93/205 (45%), Gaps = 3/205 (1%)
Frame = -3
Query: 663 VAHAKKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRK 484
++ A G + ID+ST +P +++ + E+G+ DAP++ + A+ L M G +
Sbjct: 83 LSRALAGLIVIDTSTSEPESTRRLAALCAERGVTLVDAPLARTPVEAELGRLNTMVGAEQ 142
Query: 483 EDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKV 304
F++ P+L FH G G+G V KL NN + ATAE +G G+ P+
Sbjct: 143 AVFDKIRPVLAAYCENIFHVGGPGAGHVIKLLNNFIGQAICTATAEAFAVGALAGINPQK 202
Query: 303 LLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYD-GGFKNEL--MVKDLELASGMALGI 133
L++V++ + S GL + N D G K EL KDL + +A +
Sbjct: 203 LVEVISAGAVNS----------GLFQAMAKTLNGDFTGLKFELDNARKDLRYYTHLAEMV 252
Query: 132 RSPIPLGAVATQLYRIVQSRGYGQK 58
P +G Q + G G+K
Sbjct: 253 NVPSLVGEAVHQSLATASALGQGKK 277
>UniRef50_A5WG80 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=2; Moraxellaceae|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Psychrobacter sp. PRwf-1
Length = 309
Score = 74.5 bits (175), Expect = 2e-12
Identities = 57/204 (27%), Positives = 85/204 (41%), Gaps = 1/204 (0%)
Frame = -3
Query: 657 HAKKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKED 478
H GS+ +D ++ P K G F DAPVSG GA + TL M GG +
Sbjct: 94 HLNDGSVWVDCTSGVPENAKASQAKLNAAGCEFLDAPVSGQTSGADSGTLTVMVGGSAKA 153
Query: 477 FERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLL 298
+ + H G G+G K NN L I A E +++ G+ P L
Sbjct: 154 LAYAKSAIDCFAGLIVHVGDSGAGFAVKAVNNTLFAINAWAAVEGLSVLKAHGVNPSDAL 213
Query: 297 DVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIP 118
+N +S +S++T V +P ++ Y F +LM KD +A + + P P
Sbjct: 214 ACINKASGQSFATLV------TLPDRIVNQTYPKTFTIDLMAKDCGIAIDLQTEKQVPTP 267
Query: 117 LGAVATQLYRIVQSR-GYGQKDFS 49
+ A L R ++ G DFS
Sbjct: 268 VMAQVASLVRAASNQYEPGSADFS 291
>UniRef50_Q5LNV6 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2;
Rhodobacteraceae|Rep: 3-hydroxyisobutyrate dehydrogenase
- Silicibacter pomeroyi
Length = 269
Score = 74.1 bits (174), Expect = 3e-12
Identities = 42/131 (32%), Positives = 63/131 (48%)
Frame = -3
Query: 657 HAKKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKED 478
HAK I ST+ P + + + + DAP+SG + AQ A L+FM GG D
Sbjct: 79 HAKHLDCVIICSTLSPRYVRDL-RARVPDHIALIDAPMSGAQIAAQEARLSFMLGGEPAD 137
Query: 477 FERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLL 298
+ + PL MG+ G GSG AK+ NN+L T ++ GL+ LL
Sbjct: 138 LDAAQPLFAAMGSHFHRMGPYGSGMQAKVLNNLLAAANTAMTRLVLDWADAAGLDEVALL 197
Query: 297 DVLNNSSARSW 265
+++ SS ++W
Sbjct: 198 RLIHTSSGQNW 208
>UniRef50_A0RU56 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Cenarchaeum symbiosum|Rep: 3-hydroxyisobutyrate
dehydrogenase - Cenarchaeum symbiosum
Length = 282
Score = 73.7 bits (173), Expect = 4e-12
Identities = 53/211 (25%), Positives = 92/211 (43%), Gaps = 2/211 (0%)
Frame = -3
Query: 654 AKKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDF 475
A K + D STI+P I + G+ DAPV GG A L MA G K +
Sbjct: 75 AHKDLVLCDMSTINPEGAVSISKKLADAGIRMVDAPVMGGPGAAMRGELVIMASGDKGAY 134
Query: 474 ERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLD 295
E +L + K F+ G G+ KL N+ + + ++ +E + + ++P L+
Sbjct: 135 EERRGILGAVSRKMFYLGGSGTAYSIKLAMNLQIAMLAISLSEGITLARGASVDPHKFLE 194
Query: 294 VLNNS--SARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPI 121
VLN++ + + + Y + G +++ F + KDL + A R +
Sbjct: 195 VLNSTYFNTGMSNNKAYKMIEG---------SFEPSFLLRNLKKDLHTINDHAESSRLKL 245
Query: 120 PLGAVATQLYRIVQSRGYGQKDFSFVFQLLK 28
PL +A ++Y G+G D++ + LK
Sbjct: 246 PLSTLAEEVYSEAVKGGFGDLDYTGILAYLK 276
>UniRef50_Q6F842 Cluster: Putative 3-hydroxyisobutyrate
dehydrogenase or 2-hydroxy-3- oxopropionate reductase;
n=2; Acinetobacter|Rep: Putative 3-hydroxyisobutyrate
dehydrogenase or 2-hydroxy-3- oxopropionate reductase -
Acinetobacter sp. (strain ADP1)
Length = 291
Score = 72.5 bits (170), Expect = 8e-12
Identities = 50/208 (24%), Positives = 89/208 (42%)
Frame = -3
Query: 639 LXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLP 460
+ +D S++ N K + A ++ + D+PVSGG GA+ TL AGG + +
Sbjct: 90 IIVDFSSLSVNQTKYLADRAQQQQAIWIDSPVSGGTSGAEQGTLVIFAGGNESTIQDLGL 149
Query: 459 LLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNS 280
+ V+ + G G+GQ K+ N +++ AE + + + G++ +L L N
Sbjct: 150 IYNVLSQRVTRMGDTGTGQATKICNQLIVAANSALIAEAVALAHRAGVDTTLLAPALANG 209
Query: 279 SARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVAT 100
A S ++ P P +K + + KDL A +A IP+ A
Sbjct: 210 FADSKPFQILAPRMARQIFEPVQ------WKVQTLAKDLNNAVELATHYALDIPVAHQAL 263
Query: 99 QLYRIVQSRGYGQKDFSFVFQLLKRRKQ 16
Q GY Q D + + + ++ + Q
Sbjct: 264 HQLHSHQQNGYAQSDLATMIKQVEDQDQ 291
>UniRef50_A1CAY2 Cluster: Oxidoreductase, acting on the CH-OH group
of donors, NAD or NADP as acceptor; n=2;
Aspergillus|Rep: Oxidoreductase, acting on the CH-OH
group of donors, NAD or NADP as acceptor - Aspergillus
clavatus
Length = 436
Score = 72.5 bits (170), Expect = 8e-12
Identities = 51/174 (29%), Positives = 82/174 (47%), Gaps = 3/174 (1%)
Frame = -3
Query: 561 FTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMG-AKQFHC--GQIGSGQVAKL 391
F D PVSGG A + TL+ MAG +E +L+VM K+ + G IG+G K+
Sbjct: 121 FIDCPVSGGAKRAADGTLSIMAGAPEEALNSGREILQVMSDQKKLYLVPGGIGAGSNMKM 180
Query: 390 TNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSS 211
+ +L GI + +E M ++GL+ K + + A +W E +P +
Sbjct: 181 VHQVLAGIHILGASEAMGFAAQLGLDAKTTAAKIIGTEAWTWMHE------NRLPRMLAE 234
Query: 210 RNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVATQLYRIVQSRGYGQKDFS 49
G +++KD+ + + A P+PL + A Q+Y +GYG KD S
Sbjct: 235 DWNPGASALTIILKDVGIITTSARQHHFPVPLCSTAEQVYLSALLQGYGAKDDS 288
>UniRef50_Q8UBW3 Cluster: Oxidoredutase; n=1; Agrobacterium
tumefaciens str. C58|Rep: Oxidoredutase - Agrobacterium
tumefaciens (strain C58 / ATCC 33970)
Length = 300
Score = 72.1 bits (169), Expect = 1e-11
Identities = 59/208 (28%), Positives = 92/208 (44%)
Frame = -3
Query: 648 KGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFER 469
KG++ IDSS+I P + ++ G+ DAPVSGGV GA TLA MAGG +
Sbjct: 94 KGAVVIDSSSIAPPIAREHSSRLQAMGIHHVDAPVSGGVPGATAGTLAIMAGGDEALISG 153
Query: 468 SLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVL 289
+ + MG + + G G+GQ+ KL N ++ IT A AE M + G + + +
Sbjct: 154 LVDVFAPMG-RLTYVGPSGAGQLCKLANQQIVAITIGAVAEAMMLVEAGGASREGFRNAI 212
Query: 288 NNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGA 109
A S E++ RN+ G ++ +KDL A + +PL
Sbjct: 213 RGGFAESRILELH-------GERMVKRNFVPGGPSKFQLKDLNGVLATAKDLALTLPLTQ 265
Query: 108 VATQLYRIVQSRGYGQKDFSFVFQLLKR 25
T+ + G D S + L++
Sbjct: 266 QVTREFDDFVGDGGADIDHSGILLYLEK 293
>UniRef50_A7DWL2 Cluster: Putative dehydrogenase; n=1; Streptomyces
tendae|Rep: Putative dehydrogenase - Streptomyces tendae
Length = 293
Score = 72.1 bits (169), Expect = 1e-11
Identities = 56/205 (27%), Positives = 87/205 (42%), Gaps = 1/205 (0%)
Frame = -3
Query: 645 GSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERS 466
G++ +D++T+ P+ + G+ +A V G A++ L G + +
Sbjct: 87 GTVLVDTTTVSPSFARNTAVRLAASGVERLEACVMGNPEMAESGRLRIFTSGSHSAVDAA 146
Query: 465 LPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLN 286
+L +G + H G G KL N+L+GI AE + GL +LL+VL
Sbjct: 147 GDVLSALGQEVRHLGDAGRASALKLALNLLLGIQTAGLAEAVAFAEAAGLGRDLLLEVLL 206
Query: 285 NSSARSWSTEVYCPVPGLVPTAPSSRNY-DGGFKNELMVKDLELASGMALGIRSPIPLGA 109
S RS PV G R Y F+ LM KDLELA A + P+PL
Sbjct: 207 GSGWRS-------PVLGFRAEFMRRRTYTPAAFRTRLMHKDLELALDQATAYQLPLPLVH 259
Query: 108 VATQLYRIVQSRGYGQKDFSFVFQL 34
A + + G G +D + V ++
Sbjct: 260 RAQERFAGAIDAGRGDEDAAVVVEV 284
>UniRef50_Q20XN2 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Rhodopseudomonas palustris BisB18|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Rhodopseudomonas palustris (strain BisB18)
Length = 365
Score = 71.7 bits (168), Expect = 1e-11
Identities = 58/210 (27%), Positives = 95/210 (45%), Gaps = 1/210 (0%)
Frame = -3
Query: 651 KKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFE 472
K G++ I STI P + +++ E G G+ APV G A+ TL +A G +
Sbjct: 104 KAGAVHISMSTISPTMSRRLAAWHGECGQGYVAAPVLGNPDLARARTLFILAAGPDAAMQ 163
Query: 471 RSLPLLKVMGAKQFHCGQ-IGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLD 295
++ PLL +G K F G+ + + KL N+L +T + E + + K G++P+V D
Sbjct: 164 KARPLLDRLGQKLFVIGEDAAAANLVKLAGNVLTALTLQSMGEVLALLRKSGIDPRVGFD 223
Query: 294 VLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPL 115
+ NS + + V+ G + R G L VKDL LA A P+P
Sbjct: 224 IFTNS---LFDSRVHRTYGGKI---VDERYSPPGMTVPLAVKDLRLALAEAETNSVPMPA 277
Query: 114 GAVATQLYRIVQSRGYGQKDFSFVFQLLKR 25
++ + + G+ D+S + L R
Sbjct: 278 TSLVRDRLVAMVAHGWADLDWSALGLLAAR 307
>UniRef50_A7RG59 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 341
Score = 71.7 bits (168), Expect = 1e-11
Identities = 54/197 (27%), Positives = 90/197 (45%)
Frame = -3
Query: 651 KKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFE 472
K+GS+ ID +T D N ++ +A KG+ +AP++GG + GG ++ +
Sbjct: 110 KEGSVWIDHTTTDYNETIRLGELATSKGVHAVEAPLTGG-----QGLMTVFVGGEEKVVQ 164
Query: 471 RSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDV 292
PL+ A + G +G VAK+ +NML +A E + + K GL+ D
Sbjct: 165 DVKPLMDSYTATFLYFGPLGKATVAKVISNMLCAAHLVAAGEALMLAKKAGLDMSNFFDG 224
Query: 291 LNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLG 112
+ S+ S+ E P+ + +YD F +L KDL L +A SP+ L
Sbjct: 225 IRYSAGNSYVFETEVPL-------MFNGSYDPDFTIDLHCKDLALGREIATSNDSPLELL 277
Query: 111 AVATQLYRIVQSRGYGQ 61
+ +YR + YG+
Sbjct: 278 GLTEDIYRRAMEK-YGK 293
>UniRef50_A6F020 Cluster: Putative uncharacterized protein; n=1;
Marinobacter algicola DG893|Rep: Putative
uncharacterized protein - Marinobacter algicola DG893
Length = 286
Score = 70.1 bits (164), Expect = 4e-11
Identities = 38/119 (31%), Positives = 60/119 (50%)
Frame = -3
Query: 645 GSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERS 466
GS + +T P + + +KGLGF DAPV G GA+ L + GG + +
Sbjct: 84 GSTVVILATNSPKTMQVLAAECEDKGLGFVDAPVVFGRQGAKEGQLGSLCGGDDKQVAKI 143
Query: 465 LPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVL 289
P+L+ H G +GSGQVAK NNML +A E +++ + G++ + + + L
Sbjct: 144 TPVLESYSKAVHHVGPVGSGQVAKACNNMLHWAACVANFEVLSLAKRYGIDAQQMRETL 202
>UniRef50_A1SQ87 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=4; Bacteria|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Nocardioides sp. (strain
BAA-499 / JS614)
Length = 318
Score = 69.7 bits (163), Expect = 6e-11
Identities = 52/207 (25%), Positives = 91/207 (43%)
Frame = -3
Query: 654 AKKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDF 475
A+ ++ +D ST+ + E+G+ F APVSG + L+ + G +E +
Sbjct: 94 ARVPAVVVDCSTVSTESSAAMRAACSERGVAFLAAPVSGNGKVVRAGGLSLVVSGPEETY 153
Query: 474 ERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLD 295
ER LL +G + G+ ++AK+ +N+++G+ AE + K G+ L+
Sbjct: 154 ERVAHLLDHLGKGATYVGEGELARLAKICHNVMLGVVTQCLAEITVLAEKGGMSRAAFLE 213
Query: 294 VLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPL 115
LN S S T P A + +Y F L+ KD +L A + P+P+
Sbjct: 214 FLNKSVMGSVFTTYKTP-------AFVNLDYTPTFTPILLRKDFDLGLAAARQLDVPMPV 266
Query: 114 GAVATQLYRIVQSRGYGQKDFSFVFQL 34
A + S G ++DF+ + L
Sbjct: 267 AAATNAAVQASVSSGRVEEDFAILLDL 293
>UniRef50_A4S5A4 Cluster: Predicted protein; n=2; Ostreococcus|Rep:
Predicted protein - Ostreococcus lucimarinus CCE9901
Length = 319
Score = 69.7 bits (163), Expect = 6e-11
Identities = 57/198 (28%), Positives = 89/198 (44%), Gaps = 1/198 (0%)
Frame = -3
Query: 633 IDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLL 454
+D ST+D + I L + + F APVSGG A L F+ GG +E +
Sbjct: 118 VDCSTVDGACGEATREI-LGENVRFLAAPVSGGWRDAAKGELLFLGGGDARAYEDGARFM 176
Query: 453 KVMGAKQFHCGQIGSGQV-AKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSS 277
VMGAK++ G + AKL ++MG A E + + GL+ +L++L++S+
Sbjct: 177 DVMGAKRWLVGDSPTHAARAKLMLQIMMGNVVGALGEMHALSERAGLDSNAILEMLSHSA 236
Query: 276 ARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVATQ 97
S P+ + RN+ F+ L KDL LA +A + P+ A
Sbjct: 237 MGS-------PLTTAKGKLMADRNFAPNFQVYLQQKDLRLALNLADELDFAAPITAATNA 289
Query: 96 LYRIVQSRGYGQKDFSFV 43
Y +S G+ DF+ V
Sbjct: 290 QYLKAKSLGHANSDFAAV 307
>UniRef50_Q4WV01 Cluster: Oxidoreductase, acting on the CH-OH group
of donors, NAD or NADP as acceptor; n=7;
Pezizomycotina|Rep: Oxidoreductase, acting on the CH-OH
group of donors, NAD or NADP as acceptor - Aspergillus
fumigatus (Sartorya fumigata)
Length = 435
Score = 69.7 bits (163), Expect = 6e-11
Identities = 51/174 (29%), Positives = 79/174 (45%), Gaps = 3/174 (1%)
Frame = -3
Query: 561 FTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQ---FHCGQIGSGQVAKL 391
F D PVSGG A + TL+ MAG +E +L+VM + G +G+G K+
Sbjct: 121 FIDCPVSGGAKRAADGTLSIMAGASEEALNSGREILQVMSDQNKLYLVPGGVGAGSNMKM 180
Query: 390 TNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSS 211
+ +L GI + +E M ++GL+ K + + S A +W E L
Sbjct: 181 VHQVLAGIHILGASEAMGFAAQLGLDAKTTAEKIIGSEAWTWMHE-----NRLQRMVEED 235
Query: 210 RNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVATQLYRIVQSRGYGQKDFS 49
N G +++KD+ + + A P PL + A Q+Y +GYG KD S
Sbjct: 236 WN-PGASALTIILKDVGIITTSARQHHFPTPLCSTAEQVYLSALLQGYGPKDDS 288
>UniRef50_UPI0000EBE4FC Cluster: PREDICTED: hypothetical protein;
n=1; Bos taurus|Rep: PREDICTED: hypothetical protein -
Bos taurus
Length = 351
Score = 69.3 bits (162), Expect = 8e-11
Identities = 46/185 (24%), Positives = 80/185 (43%)
Frame = -3
Query: 591 FPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIG 412
F + + +G F +APVSG + + L +A G + +E + MG F G++G
Sbjct: 170 FQVIVSRGGRFLEAPVSGNQQLSNDGMLVILAAGDRGLYEDCSSCFQAMGKTSFFLGEVG 229
Query: 411 SGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGL 232
+ L NM+ G AE + + G + LLD+LN S + C +
Sbjct: 230 NAAKMMLIVNMVQGSFMATIAEGLTLAQVTGQSQQTLLDILNQGQLASIFLDQKC--QNI 287
Query: 231 VPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVATQLYRIVQSRGYGQKDF 52
+ N+ F + + KDL LA + + P P+ A A ++Y+ ++ D
Sbjct: 288 L-----QGNFKPDFYLKYIQKDLRLAIALGDAVNHPTPMAAAANEVYKRAKALDQSDNDM 342
Query: 51 SFVFQ 37
S V++
Sbjct: 343 SAVYR 347
>UniRef50_Q84H84 Cluster: Putative oxidoreductase; n=1; Arthrobacter
sp. BP2|Rep: Putative oxidoreductase - Arthrobacter sp.
BP2
Length = 278
Score = 69.3 bits (162), Expect = 8e-11
Identities = 43/130 (33%), Positives = 66/130 (50%), Gaps = 2/130 (1%)
Frame = -3
Query: 648 KGSLXIDSSTIDPNVPKQIFPIALEKG-LGFTDAPVSGGVMGAQNATLAFMAGGRKEDFE 472
K I ST+DP+ ++ E G + A VSGG GA+ TL+ MA G ++
Sbjct: 89 KNLTIIVMSTLDPDTMNELGQQVEEHGEVRLIAAAVSGGSTGAEAGTLSIMASGAEDVVT 148
Query: 471 RSLPLLKVMGAKQFHCG-QIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLD 295
+ P +G+ F+ G + G+ Q AKL NN+++GI A AE + G + L LL+
Sbjct: 149 AASPYFDAVGSNTFYYGSKPGNSQAAKLVNNLVLGINMNAVAEGLKFGAQYNLPEAELLN 208
Query: 294 VLNNSSARSW 265
+ S+ SW
Sbjct: 209 LFKVSTGDSW 218
>UniRef50_A1WEB7 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Verminephrobacter eiseniae EF01-2|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Verminephrobacter eiseniae (strain EF01-2)
Length = 293
Score = 69.3 bits (162), Expect = 8e-11
Identities = 55/210 (26%), Positives = 98/210 (46%), Gaps = 2/210 (0%)
Frame = -3
Query: 657 HAKKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGV--MGAQNATLAFMAGGRK 484
H +G++ I+SST++P G+ DA + GV M A +ATLA GG+
Sbjct: 77 HLPQGAVVIESSTVNPEHVHAGQKRLAPFGVDVVDASILAGVEQMAAGSATLAL--GGKP 134
Query: 483 EDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKV 304
+ RS +L + ++Q H G +G+G AK+ NN + + AE M G+ +
Sbjct: 135 DAIARSQGVLDAIASRQIHFGALGAGAAAKVINNAVAHAVMVVVAEAGAMATAAGVGCEK 194
Query: 303 LLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSP 124
L+ +L++ ++ P+ +Y GG + KD LA +A + P
Sbjct: 195 LIALLSDP-----RMGLHRPLTYRYAQRVVKGDYTGGMPLDAARKDSTLALQLAQTLGVP 249
Query: 123 IPLGAVATQLYRIVQSRGYGQKDFSFVFQL 34
+ A +Y I + G+G++D++ + +L
Sbjct: 250 LFAIQGAHSVYDIAAAAGHGRQDYAVIAKL 279
>UniRef50_A0NRG5 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding protein; n=1; Stappia aggregata IAM
12614|Rep: 6-phosphogluconate dehydrogenase, NAD-binding
protein - Stappia aggregata IAM 12614
Length = 291
Score = 69.3 bits (162), Expect = 8e-11
Identities = 52/203 (25%), Positives = 88/203 (43%)
Frame = -3
Query: 633 IDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLL 454
++ T+ + +++ A EKG F DAPVSG A++A L MAG D L
Sbjct: 92 VEMGTLSVPMAERLARAAQEKGRRFVDAPVSGATQAAKDAKLLIMAGATASDAPELAALF 151
Query: 453 KVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSA 274
V+G K G+ G+G KL NML+ AE +++ G+ + +V+ NS+A
Sbjct: 152 DVLGRKTIWLGKAGAGAAMKLGVNMLIHGLNQTLAEALSLTTAAGIPQEQAYEVVENSAA 211
Query: 273 RSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVATQL 94
+ V GL + ++ F L KD+ LA +A +P + +
Sbjct: 212 ---AAPVIAYRKGLYLDEAA---HEVSFTVALARKDVGLALELASTCGVVMPQAELNHAV 265
Query: 93 YRIVQSRGYGQKDFSFVFQLLKR 25
+ GY +D + + + +
Sbjct: 266 LKAAGQAGYDGRDMASILSFVNK 288
>UniRef50_A0JRK4 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding precursor; n=3; Actinomycetales|Rep:
6-phosphogluconate dehydrogenase, NAD-binding precursor
- Arthrobacter sp. (strain FB24)
Length = 299
Score = 68.9 bits (161), Expect = 1e-10
Identities = 56/214 (26%), Positives = 98/214 (45%), Gaps = 2/214 (0%)
Frame = -3
Query: 651 KKGSLXIDSSTIDPN-VPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDF 475
K G++ I ST+ + +P + +A E G+ DAP+SGG A L + G E
Sbjct: 88 KPGAVVILGSTVGTDAIPATVDRLA-EYGVELVDAPLSGGPKRAGEGDLLIVVGASPEAQ 146
Query: 474 ERSLPLLKVMGAKQFHCG-QIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLL 298
E++ P L+++ + G + G GQ K N +L G+ A AE + + +GL+ + L
Sbjct: 147 EKARPALELLASTLTVVGDKPGDGQALKTVNQLLCGVHIAAAAEALALADALGLDQEKTL 206
Query: 297 DVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIP 118
L +A S+ P + A + + + ++ VKD+ + P
Sbjct: 207 KALEAGAAGSFMLSNRGP---RILEAYNEGGAEVLSRLDIFVKDMGIVGKATRAAGLAAP 263
Query: 117 LGAVATQLYRIVQSRGYGQKDFSFVFQLLKRRKQ 16
+ A A QLY + Q++G D S V +++ K+
Sbjct: 264 VAAAAEQLYLLGQAQGLAAADDSAVIKVVAPTKR 297
>UniRef50_Q21AH6 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=3; Bacteria|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Rhodopseudomonas palustris
(strain BisB18)
Length = 292
Score = 67.7 bits (158), Expect = 2e-10
Identities = 52/204 (25%), Positives = 91/204 (44%), Gaps = 2/204 (0%)
Frame = -3
Query: 660 AHAKKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMG-AQNATLAFMAGGRK 484
A +G++ +D STIDP +++ + + G A G A+ + GG +
Sbjct: 84 ADLAEGAIAVDLSTIDPATSRRVSDMIAKGGRARFVACTMGKTPAMAEKGEIPLFVGGDQ 143
Query: 483 EDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMAT-AECMNMGIKMGLEPK 307
E P+ K M + F G + + KL +N L+G+T +A AE + K G++P+
Sbjct: 144 VSLEALAPVFKHMSSVVFDMGSVEGATMFKLISN-LVGMTNLAILAEGYLLARKAGIDPE 202
Query: 306 VLLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRS 127
V L + WST+ + ++ ++R F +L KDL L+ A
Sbjct: 203 VFSSALKTTGG--WSTQADIRLGWMINDDFTTR-----FAVDLAAKDLRLSVNAAATWGI 255
Query: 126 PIPLGAVATQLYRIVQSRGYGQKD 55
P P+ A ++ + ++ G G KD
Sbjct: 256 PTPVAAAGLSVFSLARAAGLGSKD 279
>UniRef50_A3H6C3 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Caldivirga maquilingensis IC-167|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Caldivirga maquilingensis IC-167
Length = 284
Score = 67.7 bits (158), Expect = 2e-10
Identities = 53/217 (24%), Positives = 100/217 (46%)
Frame = -3
Query: 663 VAHAKKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRK 484
+A+A KG + +D++T+ + + I EK L + + G A+ L GG +
Sbjct: 77 IANAAKG-IILDTTTMSLSELSNVLKIIEEKRLRYLSVRLEKGPREAERGELVLYVGGDE 135
Query: 483 EDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKV 304
F+ + +L +G + G KL +N+++ + AE + K+G++P
Sbjct: 136 GLFKEANSILSQIGTP-IYVGNHEQATALKLISNVILTANTVVLAEVSVLIRKLGMDPDT 194
Query: 303 LLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSP 124
++ L S S S ++ +P ++ NY F L ++ A A I
Sbjct: 195 VVKAL--SMGGSDSAQLRTRLPWML-----KGNYGESFSLRLARDVIDKALEYAQSIGIQ 247
Query: 123 IPLGAVATQLYRIVQSRGYGQKDFSFVFQLLKRRKQK 13
+P+ + +L RI ++ GYG KDFS + ++LK ++K
Sbjct: 248 LPMTTLIDELLRIAETTGYGSKDFSEIAEVLKVNEKK 284
>UniRef50_Q3W9L4 Cluster: Putative uncharacterized protein; n=1;
Frankia sp. EAN1pec|Rep: Putative uncharacterized
protein - Frankia sp. EAN1pec
Length = 294
Score = 67.3 bits (157), Expect = 3e-10
Identities = 38/123 (30%), Positives = 57/123 (46%)
Frame = -3
Query: 645 GSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERS 466
G + + STI P +++ A ++ + DAPVSGG A L M GG + R
Sbjct: 101 GGVVVIHSTIRPETCQRLATEAAKQEISIIDAPVSGGGDAAAQRRLLVMVGGEDDAVARC 160
Query: 465 LPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLN 286
P+L+ H G +GSGQVAKL NN + E + ++G++ VL
Sbjct: 161 RPVLETFACPVIHLGPLGSGQVAKLVNNFVFTAQVGLALETFSFAQRLGMDRAAAAQVLA 220
Query: 285 NSS 277
+ S
Sbjct: 221 HGS 223
>UniRef50_Q01PV6 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Solibacter usitatus Ellin6076|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Solibacter usitatus (strain Ellin6076)
Length = 267
Score = 67.3 bits (157), Expect = 3e-10
Identities = 52/203 (25%), Positives = 85/203 (41%), Gaps = 2/203 (0%)
Frame = -3
Query: 645 GSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERS 466
G +D +T +P + + G+ + DA V G ++ MAGGR+E F+ +
Sbjct: 67 GITMVDCTTGEPESMAAMGEKLAKSGVDYLDATVLGSSKVVRSGAAVVMAGGRRESFDAA 126
Query: 465 LPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLN 286
PL + ++ F+ G G+G KL N+ +G+ AE + + P V L+VL
Sbjct: 127 SPLFRTFASRAFYLGPFGAGARMKLVVNLALGLHRAVLAETLAFAHACEVSPTVALEVLK 186
Query: 285 NSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELM--VKDLELASGMALGIRSPIPLG 112
+A S E ++D + L +KD+ L A + PL
Sbjct: 187 AGAAYSRVME---------DKGEKMLHHDFTVEARLSQHLKDVRLILDAAAAKHAKTPLS 237
Query: 111 AVATQLYRIVQSRGYGQKDFSFV 43
V QL + + GYG D S +
Sbjct: 238 QVHRQLLEGLVTAGYGDADNSAI 260
>UniRef50_A0K107 Cluster: 2-hydroxy-3-oxopropionate reductase; n=1;
Arthrobacter sp. FB24|Rep: 2-hydroxy-3-oxopropionate
reductase - Arthrobacter sp. (strain FB24)
Length = 302
Score = 67.3 bits (157), Expect = 3e-10
Identities = 48/180 (26%), Positives = 79/180 (43%)
Frame = -3
Query: 570 GLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKL 391
GL DAP+SGG +GA+ L+ M GG E ER PL + + H G+ G+G K
Sbjct: 128 GLTVVDAPLSGGTIGAEEGRLSIMVGGPAEAVERLTPLFGLYSSTAVHFGKTGAGSTVKA 187
Query: 390 TNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSS 211
N +++ T A AE M + L+ + + L A S V
Sbjct: 188 CNQIVVAATVNALAEAMALASTAALDLEKVQTTLAGGLANS-------EVLRQKGHRWID 240
Query: 210 RNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVATQLYRIVQSRGYGQKDFSFVFQLL 31
++++GG + +KDL + +A +PL A + + + G G D + +++ L
Sbjct: 241 QDFEGGGSAKNQLKDLNFIAEIAAAHGINLPLAACLQSSFEEMIAAGDGDMDHTGIYRTL 300
>UniRef50_Q7NR40 Cluster: Probable 3-hydroxyisobutyrate
dehydrogenase; n=1; Chromobacterium violaceum|Rep:
Probable 3-hydroxyisobutyrate dehydrogenase -
Chromobacterium violaceum
Length = 296
Score = 66.9 bits (156), Expect = 4e-10
Identities = 40/126 (31%), Positives = 58/126 (46%)
Frame = -3
Query: 645 GSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERS 466
G +D T P + A G +AP++G V A + TL F+ GG + D E +
Sbjct: 94 GRRLVDLGTHQPTQLAALGAEAAAAGWPLVEAPMTGSVHDASHGTLHFLVGGAEADVEWA 153
Query: 465 LPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLN 286
PLL +G H G +G+G AKL N+L+G+ E + + GL LD L+
Sbjct: 154 SPLLWALGRGVHHLGGLGAGNTAKLALNLLVGVMAGGLGEAIALLRAHGLAVDSFLDALD 213
Query: 285 NSSARS 268
S S
Sbjct: 214 GSGLAS 219
>UniRef50_Q5LQR0 Cluster: 6-phosphogluconate dehydrogenase domain
protein; n=14; Proteobacteria|Rep: 6-phosphogluconate
dehydrogenase domain protein - Silicibacter pomeroyi
Length = 302
Score = 66.9 bits (156), Expect = 4e-10
Identities = 39/125 (31%), Positives = 59/125 (47%)
Frame = -3
Query: 663 VAHAKKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRK 484
+A ++G + ID T P ++I KG + DAP+ A++ L M G K
Sbjct: 90 LAGTREGQVVIDFGTSLPASTRRIGGDLAGKGATYLDAPLGRTPAHARDGLLNIMCSGDK 149
Query: 483 EDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKV 304
F+R P+L +G FH G +G+G KL NN T A AE + G+E +
Sbjct: 150 ATFDRVKPVLHTLGENVFHLGALGNGHTIKLINNCYSMTTACAMAEAFAIADATGIERQA 209
Query: 303 LLDVL 289
L +V+
Sbjct: 210 LYNVM 214
>UniRef50_A0R1N5 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=3; Mycobacterium|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Mycobacterium smegmatis
(strain ATCC 700084 / mc(2)155)
Length = 263
Score = 66.9 bits (156), Expect = 4e-10
Identities = 38/126 (30%), Positives = 59/126 (46%)
Frame = -3
Query: 645 GSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERS 466
G++ + +T P + I A ++G+ DAPVSGG ++ AGG + ER
Sbjct: 85 GAVLVLHTTGSPRTAEDIAARAADRGVAVVDAPVSGGPHDIAAGSVTVFAGGDADVVERV 144
Query: 465 LPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLN 286
P L H G +GSGQ KL NN + AE + + ++G++ +L L
Sbjct: 145 RPALVAYAEPLLHVGPLGSGQRVKLVNNTMFAAQIGVVAEGVRLARELGVDEPTVLSALT 204
Query: 285 NSSARS 268
+ SA S
Sbjct: 205 HGSAAS 210
>UniRef50_A0YMN9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3;
Cyanobacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Lyngbya sp. PCC 8106
Length = 371
Score = 66.5 bits (155), Expect = 5e-10
Identities = 52/179 (29%), Positives = 82/179 (45%), Gaps = 8/179 (4%)
Frame = -3
Query: 651 KKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPV---SGGVMGAQNATLAFMAGGRKE 481
+ GS+ ID +T P ++ G+ D P S G LA +A G +
Sbjct: 102 RSGSIYIDITTNSPETIHRLHQAISPLGVEMLDVPFNDCSEGATSEGGMGLAVLASGSRA 161
Query: 480 DFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVL 301
FER PLL++M + +CG+IGSG KL +N + + A +E + +G+ G+ + +
Sbjct: 162 TFERVEPLLQLMADQVLYCGEIGSGTRCKLIHNAVNAVAVQAVSEGITLGLAQGISLETI 221
Query: 300 LDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYD-----GGFKNELMVKDLELASGMAL 139
D L S +++ GL P SR D F +L+ KDL +A MA+
Sbjct: 222 WDTLRFGSFGQNPGDIH----GL-PYYWFSRRCDHLSKPPAFTVKLLHKDLRIALDMAI 275
>UniRef50_UPI0001597301 Cluster: YfjR; n=1; Bacillus
amyloliquefaciens FZB42|Rep: YfjR - Bacillus
amyloliquefaciens FZB42
Length = 286
Score = 66.1 bits (154), Expect = 7e-10
Identities = 57/214 (26%), Positives = 98/214 (45%), Gaps = 2/214 (0%)
Frame = -3
Query: 663 VAHAKKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRK 484
+A + + I STI + +Q+ +G F APV G A+ A L + G
Sbjct: 81 IAGLSENGIHISMSTISTALSEQLSAAHSGRGQSFIAAPVLGRPDAAEKAELRIITAGPA 140
Query: 483 EDFERSLPLLKVMGAKQFHCG-QIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPK 307
E +++ PLL ++ + F G + + AK++ N L+ A +E M K GLE K
Sbjct: 141 EAKKKAEPLLNILSQQVFDTGEETKTANAAKISVNFLLVSMLEALSESFLMMEKYGLEQK 200
Query: 306 VLLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYD-GGFKNELMVKDLELASGMALGIR 130
L++ + A S PV T + + ++ GFK L +KD LA A +
Sbjct: 201 QFLEI---AGALFGS-----PVYQNYGTMMAEQKFEPAGFKMSLGLKDTNLALAAAEQVS 252
Query: 129 SPIPLGAVATQLYRIVQSRGYGQKDFSFVFQLLK 28
+ +PL +A + ++G+G D++ + + LK
Sbjct: 253 AKLPLAELAKSHFESGIAQGFGDLDWAALIKCLK 286
>UniRef50_Q3WJ00 Cluster: 6-phosphogluconate dehydrogenase, NAD
binding domain; n=1; Frankia sp. EAN1pec|Rep:
6-phosphogluconate dehydrogenase, NAD binding domain -
Frankia sp. EAN1pec
Length = 438
Score = 66.1 bits (154), Expect = 7e-10
Identities = 51/169 (30%), Positives = 70/169 (41%)
Frame = -3
Query: 645 GSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERS 466
G++ + ST+ P ++I A GL DAPVSGG A L M GG +
Sbjct: 256 GAVVLVHSTVAPAQIRRIAGRAATHGLRVLDAPVSGGQPRALAGELTIMIGGDADTLADV 315
Query: 465 LPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLN 286
LL + H G +G+G AKL NN + + M G +G++P L VL
Sbjct: 316 AELLSALSNHVVHLGAVGAGSYAKLINNTMFAAQIALADDAMKAGESLGIDPAGLAAVLA 375
Query: 285 NSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMAL 139
SS+ ++ V L A S N LM + L A G L
Sbjct: 376 TSSSACIASGVRLRAGSLAGLADSPANLTLTKDATLMAEILGDAPGNGL 424
>UniRef50_A4FKN9 Cluster: 2-hydroxy-3-oxopropionate reductase; n=1;
Saccharopolyspora erythraea NRRL 2338|Rep:
2-hydroxy-3-oxopropionate reductase - Saccharopolyspora
erythraea (strain NRRL 23338)
Length = 297
Score = 66.1 bits (154), Expect = 7e-10
Identities = 49/204 (24%), Positives = 89/204 (43%)
Frame = -3
Query: 633 IDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLL 454
+D+ST P + + +G DAPVSGG A+ +L+ M GG + D + ++
Sbjct: 96 VDTSTCAPADARSLADDLHARGCAVVDAPVSGGPTAARAGSLSVMVGGTEADVAAADEVI 155
Query: 453 KVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSA 274
+ + CG G+GQ+AK N +++ AE + +G +P + + L A
Sbjct: 156 RAFAGRVVVCGGPGAGQIAKACNQLVVTAGIAVVAEALVTASALGADPAAVREALLGGYA 215
Query: 273 RSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVATQL 94
S E++ R++ G +KD+ + + G+ A A +
Sbjct: 216 ASRILELH-------GDRMLRRDFTLGAAARTQLKDIGIIRELTEGVVDNQVFEAAARAM 268
Query: 93 YRIVQSRGYGQKDFSFVFQLLKRR 22
+V+S G G D S ++++RR
Sbjct: 269 EELVESGG-GDLDHSAAVRIVERR 291
>UniRef50_A0VSV4 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding precursor; n=1; Dinoroseobacter shibae DFL
12|Rep: 6-phosphogluconate dehydrogenase, NAD-binding
precursor - Dinoroseobacter shibae DFL 12
Length = 289
Score = 66.1 bits (154), Expect = 7e-10
Identities = 56/201 (27%), Positives = 90/201 (44%), Gaps = 5/201 (2%)
Frame = -3
Query: 657 HAKKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKED 478
H + G + ID++T P + G F+DAPV+GG AQ+ L + G
Sbjct: 84 HTRPGQIWIDTTTSRPETSATLAHRLDAAGAVFSDAPVTGGPKQAQDGALTSLVGCAAAQ 143
Query: 477 FERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLL 298
F+ L+ G G+G AKL NN++ T + ++ ++G++P+ L
Sbjct: 144 FDTIASLVGTYSTAIRRFGDAGTGHAAKLLNNLVTQGTMVLLSDAFQAAGRLGVDPRALY 203
Query: 297 DVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGG-FKNELMVKDLELASGM---ALGIR 130
+V+ +ARS + + P P L +Y G F KDL A + AL R
Sbjct: 204 EVMMTGAARSGTLQKAVP-PAL------DGDYTGARFSISNAAKDLGYAEALLADALPGR 256
Query: 129 SPIPLGAVATQLYRI-VQSRG 70
+ + GA+A +L + Q RG
Sbjct: 257 ADV-AGALAARLGALAAQGRG 276
>UniRef50_Q13VQ8 Cluster: Putative dehydrogenase/oxidoreductase
protein; n=2; Burkholderiales|Rep: Putative
dehydrogenase/oxidoreductase protein - Burkholderia
xenovorans (strain LB400)
Length = 300
Score = 65.7 bits (153), Expect = 9e-10
Identities = 49/185 (26%), Positives = 77/185 (41%)
Frame = -3
Query: 570 GLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKL 391
G +A +SG F GG +E+ PLL+ + +F G G+ KL
Sbjct: 118 GANILEAELSGSPSLVLARKACFYVGGTDSVYEKCEPLLQAITDNRFFLGAFGTAVSMKL 177
Query: 390 TNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSS 211
N L+ + +A AE MN+G + G P +L VL+ + S V P+ P+
Sbjct: 178 IANYLVTVNTLAAAEAMNLGTRAGFSPDLLARVLSVGAGASAMMSVRAPIMASRKFEPA- 236
Query: 210 RNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVATQLYRIVQSRGYGQKDFSFVFQLL 31
G F + K L+L + + PL A A +R +G +D + V +LL
Sbjct: 237 ---PGSFIT--LEKYLDLGQELVSELGCSAPLYAAAVPYFRRAIEQGLQNEDIAAVIKLL 291
Query: 30 KRRKQ 16
+ Q
Sbjct: 292 EAESQ 296
>UniRef50_A5P600 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Methylobacterium sp. 4-46|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Methylobacterium sp. 4-46
Length = 290
Score = 65.7 bits (153), Expect = 9e-10
Identities = 60/216 (27%), Positives = 94/216 (43%), Gaps = 5/216 (2%)
Frame = -3
Query: 663 VAHAKKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRK 484
+A + +++ST+ P + A G+ + APVSG A+ ATL G +
Sbjct: 77 LARMAPDGVLVETSTVSPETSAALREAAEAGGILYLAAPVSGSTATAEAATLTLFCSGPE 136
Query: 483 EDFERSLPLLKVMGAKQFHCGQIGSGQVA---KLTNNMLMGITGMATAECMNMGIKMGLE 313
ER+ PLL A+ H +G G+ A KL N +G T AE + + + G+
Sbjct: 137 TALERARPLLATF-ARTIHA--VGPGEEARFLKLAINHFVGSTAQVAAEALTLARRGGVA 193
Query: 312 PKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLEL--ASGMAL 139
+L VL +S A S P+ R++ F M+KD+ L A+G A+
Sbjct: 194 WDTVLAVLGSSVAAS-------PLVAYKLDPLRRRDFSPAFSIAQMLKDMSLGVAAGEAV 246
Query: 138 GIRSPIPLGAVATQLYRIVQSRGYGQKDFSFVFQLL 31
G+ +P+ A+ LY G +D F LL
Sbjct: 247 GV--AMPVAALVRDLY--AAQAGTDLRDLDFFAALL 278
>UniRef50_A4ECY9 Cluster: Putative uncharacterized protein; n=1;
Collinsella aerofaciens ATCC 25986|Rep: Putative
uncharacterized protein - Collinsella aerofaciens ATCC
25986
Length = 359
Score = 65.7 bits (153), Expect = 9e-10
Identities = 54/194 (27%), Positives = 81/194 (41%)
Frame = -3
Query: 651 KKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFE 472
K G++ ID +T P + + I A G D PV+GG GA TL + G + D
Sbjct: 89 KPGAVLIDLTTSSPELARDIAEAAQVSGRMAFDCPVTGGESGAIAGTLTAIVGATENDIA 148
Query: 471 RSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDV 292
+L A G GQ AKL N + + + A+ M GL+ + ++
Sbjct: 149 PVRDVLSTFAANICCFDGAGKGQAAKLANQVSLAACMVGMADAMAFAELSGLDLEKTREM 208
Query: 291 LNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLG 112
+ + +S + E L P A +Y GF E +KDL LA A +P
Sbjct: 209 ILGGTGKSGAME------SLAPKALDG-DYKPGFMVEHFIKDLRLALAYADDRELALPGA 261
Query: 111 AVATQLYRIVQSRG 70
VA LY ++ + G
Sbjct: 262 DVAFTLYDMLDAIG 275
>UniRef50_Q89M84 Cluster: Blr4309 protein; n=6;
Bradyrhizobiaceae|Rep: Blr4309 protein - Bradyrhizobium
japonicum
Length = 293
Score = 64.9 bits (151), Expect = 2e-09
Identities = 39/129 (30%), Positives = 66/129 (51%)
Frame = -3
Query: 654 AKKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDF 475
AK G++ I+ ST+ + +++ +GL + D PV+G A L + G D
Sbjct: 85 AKAGTIAIECSTVSYDHAREMGRELNARGLIYIDCPVTGLPDAAAAGKLTLLVGADAADL 144
Query: 474 ERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLD 295
ER+ P L+ +G+ H G +GSG V KL NN++ I AE + + + GL+ ++L+
Sbjct: 145 ERARPYLEPIGSTIRHFGAVGSGTVYKLINNLMGAIQIAGLAEGLAIAEQAGLDMTLVLE 204
Query: 294 VLNNSSARS 268
+ A S
Sbjct: 205 SIQAGVAAS 213
>UniRef50_Q1GF31 Cluster: 6-phosphogluconate dehydrogenase
NAD-binding; n=17; Proteobacteria|Rep:
6-phosphogluconate dehydrogenase NAD-binding -
Silicibacter sp. (strain TM1040)
Length = 325
Score = 64.9 bits (151), Expect = 2e-09
Identities = 49/195 (25%), Positives = 85/195 (43%)
Frame = -3
Query: 633 IDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLL 454
++ ST D K++ + E+G + PVSGG A ++ AG + FER LP L
Sbjct: 88 MEMSTTDAAEVKRLAALVSERGGSAMECPVSGGCHRADTGNISIFAGCDRATFERMLPTL 147
Query: 453 KVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSA 274
+G + H G IGS + K+ N L + E + G++ + + SS
Sbjct: 148 TTLGRRVLHTGDIGSASILKVMTNYLATANLLTCCEALVTMKAAGIDLNTTYEAMKISSG 207
Query: 273 RSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVATQL 94
S+ E V SR D F +L+ KD+ L +A P+ + + ++
Sbjct: 208 TSFVHETESQV-----ILNGSR--DISFTMDLVKKDISLFQTIADAHGVPLEISPLLVEI 260
Query: 93 YRIVQSRGYGQKDFS 49
+ +R +G+++ S
Sbjct: 261 FTDGIAR-FGERELS 274
>UniRef50_Q98I20 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2;
Alphaproteobacteria|Rep: 3-hydroxyisobutyrate
dehydrogenase - Rhizobium loti (Mesorhizobium loti)
Length = 305
Score = 64.1 bits (149), Expect = 3e-09
Identities = 51/186 (27%), Positives = 83/186 (44%)
Frame = -3
Query: 648 KGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFER 469
KG I+ ST + ++ +A +G+ + PV+GGV A + + GG +ER
Sbjct: 88 KGGTWIEMSTNGRDEIMRLAALASAEGVETLECPVTGGVHLAAVGKITALVGGDAALYER 147
Query: 468 SLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVL 289
++ M A+ F G IGS V K+ NML I +A E + + + GL+ +
Sbjct: 148 HRAAIEAMCARSFLMGPIGSAAVIKVITNMLAFIHLVAAGEALMLAKQGGLDLAQSYHAI 207
Query: 288 NNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGA 109
SS S+ E + + +YD GF +L +KDL A GM P+ L +
Sbjct: 208 VASSGNSFVHETESQL-------VLNGSYDIGFTMDLALKDLGFALGMGKDFGVPLELAS 260
Query: 108 VATQLY 91
++
Sbjct: 261 RVNAIF 266
>UniRef50_P71825 Cluster: Uncharacterized oxidoreductase
Rv0770/MT0794; n=18; Corynebacterineae|Rep:
Uncharacterized oxidoreductase Rv0770/MT0794 -
Mycobacterium tuberculosis
Length = 295
Score = 64.1 bits (149), Expect = 3e-09
Identities = 54/193 (27%), Positives = 77/193 (39%), Gaps = 6/193 (3%)
Frame = -3
Query: 657 HAKKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKED 478
HAK G++ STI + +G+ DAPVSGG A LA M G E
Sbjct: 89 HAKPGTIVAIHSTIADTTAVDLAEKLKPQGIHIVDAPVSGGAAAAAKGELAVMVGADDEA 148
Query: 477 FERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLL 298
F+R + H G+ G+G KL NML ++ A AE + GL+ L
Sbjct: 149 FQRIKEPFSRWASLLIHAGEPGAGTRMKLARNMLTFVSYAAAAEAQRLAEACGLDLVALG 208
Query: 297 DVLNNSSARSWST------EVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALG 136
V+ +S + + P+ P P + G L KDL LA +
Sbjct: 209 KVVRHSDSFTGGAGAIMFRNTTAPMEPADPLRPLLEHTRG-----LGEKDLSLALALGEV 263
Query: 135 IRSPIPLGAVATQ 97
+ +PL +A Q
Sbjct: 264 VSVDLPLAQLALQ 276
>UniRef50_Q39KK8 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=34; Bacteria|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Burkholderia sp. (strain
383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086
/ R18194))
Length = 289
Score = 63.7 bits (148), Expect = 4e-09
Identities = 53/216 (24%), Positives = 95/216 (43%), Gaps = 2/216 (0%)
Frame = -3
Query: 663 VAHAKKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRK 484
+A A +G + ++ +T+ + + + +G+ + APV G A A L MAGG
Sbjct: 78 LAQAPRGLIHVNMATVSVALAESLAHAHASRGIHYVAAPVMGRPDVAAAARLTIMAGGPA 137
Query: 483 EDFERSLPLLKVMGAKQFHCGQIGS-GQVAKLTNNMLMGITGMATAECMNMGIKMGLEPK 307
E +R PL +G K + G + VAK+ N + E + G+ +
Sbjct: 138 EAIDRVQPLFDAIGQKTWRFGSLPQHANVAKIAANFTLASAIETLGEASALLGAHGVAMR 197
Query: 306 VLLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYD-GGFKNELMVKDLELASGMALGIR 130
LDV+ S + VY ++ + R+Y+ FK L +KD+ LA +
Sbjct: 198 DFLDVITGS---VFPGPVYEGYGSMI----AERHYEPARFKARLGLKDVRLALEAGDAVS 250
Query: 129 SPIPLGAVATQLYRIVQSRGYGQKDFSFVFQLLKRR 22
P+P+ +V + G G++DF+ + ++ RR
Sbjct: 251 VPLPVASVVRDNLLDALAHGGGEQDFAVLGEVALRR 286
>UniRef50_A7H7Z5 Cluster: 6-phosphogluconate dehydrogenase
NAD-binding; n=2; Anaeromyxobacter|Rep:
6-phosphogluconate dehydrogenase NAD-binding -
Anaeromyxobacter sp. Fw109-5
Length = 293
Score = 62.5 bits (145), Expect = 9e-09
Identities = 52/206 (25%), Positives = 83/206 (40%)
Frame = -3
Query: 651 KKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFE 472
+ G + +D ST + + A +G GF PV G A+ A L +AGG E
Sbjct: 87 RDGDVLVDMSTAGVRAARSVSERAAARGAGFVACPVLGSRSAAEQAQLVLVAGGPAVARE 146
Query: 471 RSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDV 292
R+ P L + A+ F + KL N + G E + +G G+ L++V
Sbjct: 147 RARPALHAVSARIFELEDAAQAALMKLCVNAIGGAMITGFGEALALGQAGGVPVAKLVEV 206
Query: 291 LNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLG 112
L A S+ + +Y LV R++ F L KD LA A + + P+
Sbjct: 207 L---QASSFHSPLYLMKGELV----ERRDWAPRFAIALAEKDQRLAQEAAADLGAKTPVN 259
Query: 111 AVATQLYRIVQSRGYGQKDFSFVFQL 34
+++ G KD + V +L
Sbjct: 260 DTVRRVFADAAQSGRADKDIAAVAEL 285
>UniRef50_A7CWR7 Cluster: 6-phosphogluconate dehydrogenase
NAD-binding; n=1; Opitutaceae bacterium TAV2|Rep:
6-phosphogluconate dehydrogenase NAD-binding -
Opitutaceae bacterium TAV2
Length = 288
Score = 62.5 bits (145), Expect = 9e-09
Identities = 50/205 (24%), Positives = 82/205 (40%)
Frame = -3
Query: 645 GSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERS 466
G + + SSTIDP + L G + +AP +G A+ F GG +
Sbjct: 93 GKVVVQSSTIDPESSSRFREAVLAAGARYLEAPFTGSKPAAEQRQTVFYLGGEADLIAEL 152
Query: 465 LPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLN 286
PLL ++ + G + KL N+ + I E + + + G+ D ++
Sbjct: 153 EPLLALISGTRLRIGDNRQATLLKLAMNLNLAIQMEGLGEALTLARRAGISDDTFFDAMS 212
Query: 285 NSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAV 106
+ S ++ P AP F + M KD+ LA G P+ L AV
Sbjct: 213 RNVGNSGLVKLKEPKLRGADFAPQ-------FSVKHMHKDMRLAVGTREAAGFPL-LAAV 264
Query: 105 ATQLYRIVQSRGYGQKDFSFVFQLL 31
+L +S G+G DF+ + +LL
Sbjct: 265 RARLGE-AESAGWGNDDFASLIRLL 288
>UniRef50_A3Y8R5 Cluster: Putative dehydrogenase; n=1; Marinomonas
sp. MED121|Rep: Putative dehydrogenase - Marinomonas sp.
MED121
Length = 297
Score = 62.5 bits (145), Expect = 9e-09
Identities = 51/177 (28%), Positives = 77/177 (43%), Gaps = 2/177 (1%)
Frame = -3
Query: 657 HAKKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKED 478
+A+ G+ ++ST + + +++ IA L DAPV+GG GA TL + G ++
Sbjct: 87 NAQAGATWFETSTNELSEWEKVKAIA-PSHLSLIDAPVTGGAEGAAAGTLTMLLGIDEQI 145
Query: 477 FERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLL 298
+ +L G G+G V KL L + E + MG K L VL
Sbjct: 146 LTKFTSMLNAFTKNAIRMGPSGAGYVTKLAQLHLNYLVAQGIGEALMMGAKAELNLDVLH 205
Query: 297 DVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELAS--GMALGI 133
+L NS A+S+ + Y P +YD F L KD+ L + G LGI
Sbjct: 206 KILQNSCAQSYVVDSYIP-------KVLDGSYDQSFALGLATKDMRLITELGSHLGI 255
>UniRef50_A6RMW8 Cluster: Putative uncharacterized protein; n=2;
Sclerotiniaceae|Rep: Putative uncharacterized protein -
Botryotinia fuckeliana B05.10
Length = 446
Score = 62.5 bits (145), Expect = 9e-09
Identities = 50/177 (28%), Positives = 77/177 (43%), Gaps = 2/177 (1%)
Frame = -3
Query: 573 KGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHC--GQIGSGQV 400
K + DAPVSGG A TL +A G ++ + + P+L M A H G +G+G
Sbjct: 121 KDVELVDAPVSGGTSRAALGTLVILASGPEKSLDAAKPVLDAM-ADPLHMIPGGLGAGTK 179
Query: 399 AKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTA 220
K+ + L GI + +E M +GL K D L SS SW + VP
Sbjct: 180 VKMVHQALAGIHMIMASEAMGFAAFLGLNTKQAFDYLVKSSGESWM------LGNRVPHM 233
Query: 219 PSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVATQLYRIVQSRGYGQKDFS 49
+ + N + VKD+ + + ++ P+ L + A Q+ G+G D S
Sbjct: 234 LENDLHPYSALN-IFVKDMGIVTADGRRVKCPLFLCSAAEQVLASGVRSGFGLDDDS 289
>UniRef50_O34969 Cluster: Uncharacterized oxidoreductase yfjR; n=1;
Bacillus subtilis|Rep: Uncharacterized oxidoreductase
yfjR - Bacillus subtilis
Length = 261
Score = 62.5 bits (145), Expect = 9e-09
Identities = 57/209 (27%), Positives = 93/209 (44%), Gaps = 2/209 (0%)
Frame = -3
Query: 648 KGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFER 469
+ + I STI +++ EKG F APV G A A L + G E +
Sbjct: 61 ENGIHISMSTISVEFSEKLAAAHAEKGQFFLAAPVLGRPDAAAKAALRIITAGPAEAKQA 120
Query: 468 SLPLLKVMGAKQFHCGQIG-SGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDV 292
+ PLL + + F G+ + AK++ N L+ A +E M K GLE K L++
Sbjct: 121 AKPLLDSLSQQIFDVGEESKTANAAKISINFLLVSMLEALSESFLMMEKYGLEQKQFLEI 180
Query: 291 LNNSSARSWSTEVYCPVPGLVPTAPSSRNYD-GGFKNELMVKDLELASGMALGIRSPIPL 115
+SA S PV T + + ++ GFK L +KD LA A + + +PL
Sbjct: 181 ---ASALFGS-----PVYQNYGTIMAEQKFEPAGFKMSLGLKDTNLALAAAKRVSANLPL 232
Query: 114 GAVATQLYRIVQSRGYGQKDFSFVFQLLK 28
+A + +G+G D++ + + +K
Sbjct: 233 AELAKSHFESGIEKGFGDLDWAALIKCIK 261
>UniRef50_A5CN67 Cluster: Putative beta-hydroxyacid dehydrogenase;
n=1; Clavibacter michiganensis subsp. michiganensis
NCPPB 382|Rep: Putative beta-hydroxyacid dehydrogenase -
Clavibacter michiganensis subsp. michiganensis (strain
NCPPB 382)
Length = 291
Score = 61.7 bits (143), Expect = 2e-08
Identities = 34/127 (26%), Positives = 62/127 (48%), Gaps = 1/127 (0%)
Frame = -3
Query: 651 KKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFE 472
+ G++ + SST+ ++I +A E + F DAPV G A+ L + G ++D
Sbjct: 80 RPGAVVLQSSTVGVEGTRRIAALAAEHAVRFVDAPVLGTRGPAEQGLLVHLVSGSEDDLA 139
Query: 471 RSLPLLKVMGAKQFHCG-QIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLD 295
+ P+L+ G++ G G G KL N + AT + + + +G+EP++ LD
Sbjct: 140 VARPVLEATGSRTVVAGSDAGPGSALKLACNAWIASITAATGQSLGLARLLGVEPRLFLD 199
Query: 294 VLNNSSA 274
+ +A
Sbjct: 200 AIAGGAA 206
>UniRef50_Q0RIL5 Cluster: Putative uncharacterized protein; n=1;
Frankia alni ACN14a|Rep: Putative uncharacterized
protein - Frankia alni (strain ACN14a)
Length = 493
Score = 61.3 bits (142), Expect = 2e-08
Identities = 45/183 (24%), Positives = 80/183 (43%)
Frame = -3
Query: 663 VAHAKKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRK 484
+A A G + ST++ V ++ + E +GF D V+ G A + +A + GG +
Sbjct: 87 LAGAHPGLTIVLLSTVELAVVHELAALCAEHDVGFLDCGVTPGDRAADHGMVAIV-GGDE 145
Query: 483 EDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKV 304
E + P+L + HCG +G+G V K+ N++ + A E + G+ P
Sbjct: 146 ATVEAARPVLDDWARRVVHCGPLGAGMVTKIARNVVTYGSWRAVFEASALARAAGVNPAR 205
Query: 303 LLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSP 124
L +V++ + + + G P + G LM KDL+ A +A +
Sbjct: 206 LAEVIDTADPEGHTLLTLLRLRGGDDRLPQAA---GRKIQPLMTKDLDAARDLATALDVD 262
Query: 123 IPL 115
+PL
Sbjct: 263 VPL 265
>UniRef50_Q6RXW5 Cluster: Succinic semialdehyde dehydrogenase; n=2;
Rhodococcus|Rep: Succinic semialdehyde dehydrogenase -
Rhodococcus sp. TK6
Length = 262
Score = 60.5 bits (140), Expect = 4e-08
Identities = 41/133 (30%), Positives = 65/133 (48%), Gaps = 1/133 (0%)
Frame = -3
Query: 660 AHAKKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLA-FMAGGRK 484
AH + +T+ P ++I P A G +APVSGG GA++ ++ F+AG
Sbjct: 80 AHTAQPLTVFVHTTLAPADARKILPSA-PAGWRVFEAPVSGGPQGARHGSMTVFLAGPAP 138
Query: 483 EDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKV 304
D E +L L+ + + F G + KL NN L ATA +N+ + G+ K
Sbjct: 139 TDAENAL--LEDISGRVFQMESYGQPALVKLLNNALATYNLAATARMLNLAAEHGVPAKD 196
Query: 303 LLDVLNNSSARSW 265
L +V+ S+ +SW
Sbjct: 197 LFEVIGVSTGQSW 209
>UniRef50_Q1B326 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding protein precursor; n=7; Bacteria|Rep:
6-phosphogluconate dehydrogenase, NAD-binding protein
precursor - Mycobacterium sp. (strain MCS)
Length = 299
Score = 60.5 bits (140), Expect = 4e-08
Identities = 50/209 (23%), Positives = 95/209 (45%), Gaps = 2/209 (0%)
Frame = -3
Query: 663 VAHAKKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRK 484
VA + ++ + SSTI + +++ E G F APV G A A L +A G
Sbjct: 83 VASLRPDAIHVSSSTISLALAERLTAAHAEGGSRFVSAPVFGRPEAAAAAKLFVVAAGAP 142
Query: 483 EDFERSLPLLKVMGAKQFHCG-QIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPK 307
+ E P+ + +G + F G + + + K++ N L+ + E M + K G++
Sbjct: 143 DTVEALAPVFEAIGQRTFVVGTEPKAANLVKVSGNFLIASVIESLGEAMALVAKGGVDVD 202
Query: 306 VLLDVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYD-GGFKNELMVKDLELASGMALGIR 130
LD+L ++ + Y GL+ + R ++ GF +KD+ LA G++
Sbjct: 203 QYLDLLTST---LFDAPAYRTYGGLL----ARREFEPAGFSATGGLKDVRLALEAGDGLQ 255
Query: 129 SPIPLGAVATQLYRIVQSRGYGQKDFSFV 43
P+P+ ++ + + + G G D+S +
Sbjct: 256 VPLPIASLLRDRFLTLLATGGGHLDWSAI 284
>UniRef50_A3PRM1 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding precursor; n=2; Rhodobacter sphaeroides|Rep:
6-phosphogluconate dehydrogenase, NAD-binding precursor
- Rhodobacter sphaeroides (strain ATCC 17029 / ATH
2.4.9)
Length = 288
Score = 60.5 bits (140), Expect = 4e-08
Identities = 51/200 (25%), Positives = 86/200 (43%)
Frame = -3
Query: 654 AKKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDF 475
A G + ++ ST+ P+ + + A G F PV G V A L AGG E
Sbjct: 81 ALAGRIVVEMSTLLPDQAEALEAQATALGAQFLHCPVGGTVAPALKGQLLGFAGGPAETL 140
Query: 474 ERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLD 295
+R+ P+L+ + + H G +G+ KL N+ + + E + + G+ + +
Sbjct: 141 DRARPVLERLCRRVEHLGPVGAAARMKLAVNLPLALYWQTLGESLLLLRGAGVPAEQAIG 200
Query: 294 VLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPL 115
++ SS + V +V T + + G F + KDL LA +A + +PL
Sbjct: 201 LMAESSGGPAVLKNRAQV--VVETLEGA-DQRGTFDIAGLAKDLHLALALAEREGAALPL 257
Query: 114 GAVATQLYRIVQSRGYGQKD 55
A A + YR G G+ D
Sbjct: 258 SAAAEERYRAALEAGLGRFD 277
>UniRef50_A1UJF3 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=4; Actinomycetales|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Mycobacterium sp. (strain KMS)
Length = 272
Score = 60.5 bits (140), Expect = 4e-08
Identities = 35/126 (27%), Positives = 56/126 (44%)
Frame = -3
Query: 645 GSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERS 466
G+ + +T P+ + + + G+ DAPVSGG + GG + ER+
Sbjct: 87 GATLVIHTTGSPDTARLLAARGRDHGVDVVDAPVSGGPHDIAAGAVTLFVGGSEAAVERA 146
Query: 465 LPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLN 286
P+L G H G +G+GQ KL NN + E + +G +G+ LL L
Sbjct: 147 RPVLAAYGDPILHVGPLGAGQSVKLVNNTVFAAQIGLLREAVRLGGALGVAEPDLLTALT 206
Query: 285 NSSARS 268
+ S+ S
Sbjct: 207 HGSSSS 212
>UniRef50_Q74D68 Cluster: 3-hydroxyisobutyrate dehydrogenase family
protein; n=7; Desulfuromonadales|Rep:
3-hydroxyisobutyrate dehydrogenase family protein -
Geobacter sulfurreducens
Length = 288
Score = 60.1 bits (139), Expect = 5e-08
Identities = 53/207 (25%), Positives = 84/207 (40%)
Frame = -3
Query: 645 GSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERS 466
G++ +D T ++ A + + F DAPV G A N L +AGG R
Sbjct: 89 GTILVDMGTHSLTSTMEMADEAAKHRVMFLDAPVWGTKEHAANGLLTILAGGDPSLVGRC 148
Query: 465 LPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLN 286
L G H G IG K N++ A AE + G K+G +L+VL+
Sbjct: 149 RELFSFFGLNIIHVGSIGDATRMKFVVNLVQAELMQALAESIVFGEKLGFTADRILEVLD 208
Query: 285 NSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIPLGAV 106
+ S ++ + +RN + +E + LE A + L +P V
Sbjct: 209 SGGVAS---PLFHSKGRSIARGDFTRNLALKYVHEQLELVLEKAEKLGL----ELPAAKV 261
Query: 105 ATQLYRIVQSRGYGQKDFSFVFQLLKR 25
A Y G G++DFS V ++L++
Sbjct: 262 ACATYEQGVKDGRGEEDFSSVVKVLRK 288
>UniRef50_Q9I1R8 Cluster: Probable dehydrogenase; n=7; Pseudomonas
aeruginosa|Rep: Probable dehydrogenase - Pseudomonas
aeruginosa
Length = 291
Score = 59.7 bits (138), Expect = 6e-08
Identities = 49/216 (22%), Positives = 99/216 (45%), Gaps = 1/216 (0%)
Frame = -3
Query: 654 AKKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDF 475
A+ G + + ST+ + + + +GL F APV G A+ L + GG +E
Sbjct: 82 ARPGLIHLSMSTLSLDCVEALDQAHQRQGLAFVAAPVFGRTDVAEAGKLNIVVGGPEEAI 141
Query: 474 ERSLPLLKVMGAKQFHCGQIGSGQVA-KLTNNMLMGITGMATAECMNMGIKMGLEPKVLL 298
E+ LL++MG K + G+ G +A K++ N ++ + E + + ++G+EP +
Sbjct: 142 EQVKALLEIMGQKTWFFGKDPRGAMAVKISGNFMIASAIESMGESVALVKRLGVEPGRFM 201
Query: 297 DVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDGGFKNELMVKDLELASGMALGIRSPIP 118
+++ S+ + VY P R F+ L +KD++LA P+P
Sbjct: 202 ELM---SSTLFDAPVY---RNYGPQIVEQRFTPARFRLVLGLKDVDLALSAGKRHNVPLP 255
Query: 117 LGAVATQLYRIVQSRGYGQKDFSFVFQLLKRRKQKL 10
L ++ + + G G+ D++ + ++ R ++
Sbjct: 256 LASLLHDVLLEAIAHGDGESDWTALAKVALSRSGQI 291
>UniRef50_Q221W9 Cluster: 2-hydroxy-3-oxopropionate reductase; n=1;
Rhodoferax ferrireducens T118|Rep:
2-hydroxy-3-oxopropionate reductase - Rhodoferax
ferrireducens (strain DSM 15236 / ATCC BAA-621 / T118)
Length = 303
Score = 59.3 bits (137), Expect = 8e-08
Identities = 35/136 (25%), Positives = 60/136 (44%)
Frame = -3
Query: 651 KKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFE 472
K G + +D ST P+ +++ KG F DA ++G A L + GG E
Sbjct: 96 KPGCVVVDCSTSLPDSTRRVAQAIAAKGGQFLDAAMTGTPKHADEGKLNLLVGGDPEVLT 155
Query: 471 RSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDV 292
P+ + F+CG + +G KL + ++ AE + K G+ +VL DV
Sbjct: 156 SVRPVFALFAENIFYCGAVSAGHTTKLLHQFVVLGNAAILAEAFSCASKTGVNLEVLCDV 215
Query: 291 LNNSSARSWSTEVYCP 244
+ + A S + + + P
Sbjct: 216 IASGGANSTAFQRFRP 231
>UniRef50_Q1V2K7 Cluster: NADP oxidoreductase, coenzyme
F420-dependent:6- phosphogluconatedehydrogenase,
NAD-binding:3-hydroxyacyl-CoA; n=1; Candidatus
Pelagibacter ubique HTCC1002|Rep: NADP oxidoreductase,
coenzyme F420-dependent:6-
phosphogluconatedehydrogenase,
NAD-binding:3-hydroxyacyl-CoA - Candidatus Pelagibacter
ubique HTCC1002
Length = 284
Score = 58.8 bits (136), Expect = 1e-07
Identities = 36/125 (28%), Positives = 57/125 (45%)
Frame = -3
Query: 642 SLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERSL 463
+L ID +T D N + I K + + + PV GG + A+ L + GG +E+F+++
Sbjct: 88 TLIIDITTHDQNGSIEANKIFKSKNINYIECPVMGGPVQAEEGVLGGIIGGSEENFKKAE 147
Query: 462 PLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNN 283
LK F+ G++G G +KL NN L + K ++ K L DV
Sbjct: 148 VFLKAFCKDYFYFGEVGMGTKSKLLNNFLTLGNATLIVHMIKGAKKFDIDLKKLYDVAKL 207
Query: 282 SSARS 268
S S
Sbjct: 208 GSGNS 212
>UniRef50_A6R0U9 Cluster: Predicted protein; n=1; Ajellomyces
capsulatus NAm1|Rep: Predicted protein - Ajellomyces
capsulatus NAm1
Length = 444
Score = 58.8 bits (136), Expect = 1e-07
Identities = 50/182 (27%), Positives = 75/182 (41%), Gaps = 3/182 (1%)
Frame = -3
Query: 561 FTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQ---FHCGQIGSGQVAKL 391
F DAPVSGG A TL MAGG E LL M F G +G+G K+
Sbjct: 124 FIDAPVSGGARKAGEGTLTIMAGGSDAALEEGKFLLTEMADTNKLYFVPGGVGAGSNMKM 183
Query: 390 TNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSARSWSTEVYCPVPGLVPTAPSS 211
+ + I +A +E M +GL + + +S A S+ E C
Sbjct: 184 IHQVFAAIHILAASEVMGFAAHLGLNAEEAGKAVTSSLAWSFMHENRC------ERMLRE 237
Query: 210 RNYDGGFKNELMVKDLELASGMALGIRSPIPLGAVATQLYRIVQSRGYGQKDFSFVFQLL 31
Y G +++KD+ + + A P PL ++A Q++ G+G D + +L
Sbjct: 238 DYYPGASAITIILKDVGIVTAAARLHNFPTPLCSIAEQIFITALPLGFGGDDDASAVRLY 297
Query: 30 KR 25
R
Sbjct: 298 YR 299
>UniRef50_Q8T079 Cluster: LD22344p; n=2; Sophophora|Rep: LD22344p -
Drosophila melanogaster (Fruit fly)
Length = 602
Score = 58.4 bits (135), Expect = 1e-07
Identities = 44/200 (22%), Positives = 84/200 (42%), Gaps = 2/200 (1%)
Frame = -3
Query: 633 IDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLL 454
++ STIDP+ I + + +A + G A L +AGG + FE
Sbjct: 407 VEMSTIDPDTSLDIGEGIKQCNGRYLEAQIHGSRQEAAEGMLIILAGGDRSVFEECHSCF 466
Query: 453 KVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVLNNSSA 274
K + F G IG+ L ++G++ + AE + + + + ++D+ + +S
Sbjct: 467 KTIAKNTFFLGNIGNACKVNLILQTILGVSLVGLAEALALADRFSISLNDIIDIFDLTSM 526
Query: 273 RSWSTEVYCPVPGLVPTAPSSRNYDGGFKNEL--MVKDLELASGMALGIRSPIPLGAVAT 100
+S P L+ D + L M +DL L MA + +P+ ++
Sbjct: 527 KS---------PMLLAKGKEMAKGDFNPQQPLSHMQRDLRLVLNMAENLDQSMPVTSITN 577
Query: 99 QLYRIVQSRGYGQKDFSFVF 40
++++ + GY + D S VF
Sbjct: 578 EVFKHTKRLGYSEHDSSAVF 597
>UniRef50_Q98K09 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=7;
Alphaproteobacteria|Rep: 3-hydroxyisobutyrate
dehydrogenase - Rhizobium loti (Mesorhizobium loti)
Length = 312
Score = 58.0 bits (134), Expect = 2e-07
Identities = 36/123 (29%), Positives = 53/123 (43%)
Frame = -3
Query: 651 KKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFE 472
KKGS+ +D ST DP + G+ + DAP+S A TL M G F
Sbjct: 93 KKGSVVVDCSTSDPVSTVALAAELKALGIDYVDAPLSRTPKEAWEGTLDAMVGAPDAVFA 152
Query: 471 RSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDV 292
R P+++ + H G G G KL NN + +E + + K+G+ P V
Sbjct: 153 RVKPVIETWAGRIVHIGDTGDGHRMKLLNNFISLGYAAIYSEALALAEKVGISPPRFDSV 212
Query: 291 LNN 283
+ N
Sbjct: 213 IRN 215
>UniRef50_Q5GUM4 Cluster: Dehydrogenase; n=5;
Gammaproteobacteria|Rep: Dehydrogenase - Xanthomonas
oryzae pv. oryzae
Length = 335
Score = 56.8 bits (131), Expect = 4e-07
Identities = 53/210 (25%), Positives = 90/210 (42%), Gaps = 2/210 (0%)
Frame = -3
Query: 645 GSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERS 466
GS+ ++ +TI + + + E+G+ + APV G V A+ L +AGG R
Sbjct: 128 GSVHVNMATISVALAHALTALHAERGVAYVAAPVLGRVDVAEAGKLNILAGGDDVAVARV 187
Query: 465 LPLLKVMGAKQFHCGQI-GSGQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLLDVL 289
P+ +G K +H G+ AKL N+ + A AE + G++ L +L
Sbjct: 188 QPMFDALGQKTWHIGRAPEQANAAKLAANVCLASAIGAMAEASALARGHGVDTTQFLGML 247
Query: 288 NNSSARSWSTEVYCPVPGLVPTAPSSRNY-DGGFKNELMVKDLELASGMALGIRSPIPLG 112
++ ++ Y L+ R Y GF L KD++LA + P+PLG
Sbjct: 248 TST---LFAAPAYQGYGRLI----MQRAYLPAGFTATLGRKDVDLAIQAGADKQVPMPLG 300
Query: 111 AVATQLYRIVQSRGYGQKDFSFVFQLLKRR 22
V + G G D++ + ++ RR
Sbjct: 301 EVLRAGLDEAIAHGDGHADWAVLAEVSARR 330
>UniRef50_Q2JEN4 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Frankia sp. CcI3|Rep:
6-phosphogluconate dehydrogenase, NAD-binding - Frankia
sp. (strain CcI3)
Length = 290
Score = 56.8 bits (131), Expect = 4e-07
Identities = 49/213 (23%), Positives = 92/213 (43%), Gaps = 2/213 (0%)
Frame = -3
Query: 654 AKKGSLXIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDF 475
A G+L ++ +T+ + Q E GL + APV G A+ L + G +
Sbjct: 81 APAGALHVNMATVSTALAIQARREHAEHGLRYLAAPVFGRTDAARAGNLTIVTSGDPDTI 140
Query: 474 ERSLPLLKVMGAKQFHCGQIGS-GQVAKLTNNMLMGITGMATAECMNMGIKMGLEPKVLL 298
PL V+G + + G + K+ N L+ + A AE + G+ P +
Sbjct: 141 AEVQPLFDVLGRRTWTVGDAPEHANLVKILGNYLIACSIEAMAEASAVIEAGGMNPATFI 200
Query: 297 DVLNNSSARSWSTEVYCPVPGLVPTAPSSRNYDG-GFKNELMVKDLELASGMALGIRSPI 121
+VL ++ ++ V+ ++ +R+Y+ F+ L +KD++LA L P+
Sbjct: 201 EVLTDN---LFTGPVFTGYGRMI----GNRDYEPVNFRLPLGLKDVQLALASGLERNVPL 253
Query: 120 PLGAVATQLYRIVQSRGYGQKDFSFVFQLLKRR 22
P G V + + G +D++ V + +RR
Sbjct: 254 PFGGVLRDAFVDALAHGQTDQDWAAVTETARRR 286
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 747,500,874
Number of Sequences: 1657284
Number of extensions: 16934496
Number of successful extensions: 52797
Number of sequences better than 10.0: 317
Number of HSP's better than 10.0 without gapping: 49752
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 52535
length of database: 575,637,011
effective HSP length: 98
effective length of database: 413,223,179
effective search space used: 50826451017
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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