Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P16_F_N24
(813 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X59618-1|CAA42181.1| 389|Homo sapiens small subunit ribonucleot... 317 4e-86
S40301-1|AAA09577.1| 389|Homo sapiens ribonucleotide reductase ... 317 4e-86
BC030154-1|AAH30154.1| 389|Homo sapiens ribonucleotide reductas... 317 4e-86
BC001886-1|AAH01886.1| 389|Homo sapiens ribonucleotide reductas... 317 4e-86
AY032750-1|AAK51163.1| 389|Homo sapiens ribonucleotide reductas... 317 4e-86
AC104794-2|AAX93099.1| 389|Homo sapiens unknown protein. 317 4e-86
DQ027001-1|AAY29059.1| 351|Homo sapiens ribonucleotide reductas... 301 2e-81
BC130628-1|AAI30629.1| 351|Homo sapiens ribonucleotide reductas... 301 2e-81
BC117496-1|AAI17497.1| 351|Homo sapiens ribonucleotide reductas... 301 2e-81
BC108261-1|AAI08262.1| 351|Homo sapiens ribonucleotide reductas... 301 2e-81
AK001965-1|BAA92005.1| 351|Homo sapiens protein ( Homo sapiens ... 301 2e-81
AB166671-1|BAD12267.1| 351|Homo sapiens p53-inducible ribonucle... 301 2e-81
AB036532-1|BAA92493.1| 351|Homo sapiens ribonucleotide reductas... 301 2e-81
AB036063-1|BAA92434.1| 351|Homo sapiens ribonucleotide reductas... 301 2e-81
AB163437-1|BAD11774.1| 299|Homo sapiens p53-inducible ribonucle... 231 3e-60
BC042468-1|AAH42468.1| 285|Homo sapiens Similar to ribonucleoti... 230 4e-60
BC068260-1|AAH68260.1| 601|Homo sapiens PRODH protein protein. 34 0.53
U82381-1|AAB88789.1| 516|Homo sapiens proline dehydrogenase/pro... 33 1.2
BC121809-1|AAI21810.1| 492|Homo sapiens PRODH protein protein. 33 1.2
BC118597-1|AAI18598.1| 492|Homo sapiens PRODH protein protein. 33 1.2
BC094736-1|AAH94736.1| 544|Homo sapiens PRODH protein protein. 33 1.2
AF120278-1|AAD24775.1| 516|Homo sapiens proline dehydrogenase p... 33 1.2
BC028932-1|AAH28932.1| 172|Homo sapiens Similar to ribonucleoti... 33 1.6
U79754-1|AAF21464.1| 600|Homo sapiens proline oxidase 2 protein. 30 8.7
>X59618-1|CAA42181.1| 389|Homo sapiens small subunit ribonucleotide
reductase protein.
Length = 389
Score = 317 bits (778), Expect = 4e-86
Identities = 154/248 (62%), Positives = 179/248 (72%), Gaps = 7/248 (2%)
Frame = +2
Query: 89 MAPTVDKENLH----SGINGENRVQTKSPMKNS-VLATKNDNLTEEMDLDKNFEEFDP-- 247
+AP D + L G++ ++ T + + VLA+K + + + P
Sbjct: 8 LAPITDPQQLQLSPLKGLSLVDKENTPPALSGTRVLASKTARRIFQEPTEPKTKAAAPGV 67
Query: 248 QKEPLLRENPRRFVIFPIQYPDIWQMYKKAEASFWTVEEVDLSKDLSDWETLKDSERHFI 427
+ EPLLRENPRRFVIFPI+Y DIWQMYKKAEASFWT EEVDLSKD+ WE+LK ER+FI
Sbjct: 68 EDEPLLRENPRRFVIFPIEYHDIWQMYKKAEASFWTAEEVDLSKDIQHWESLKPEERYFI 127
Query: 428 KHVLAFFAASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENVHSEMYSLLIDTYIRDP 607
HVLAFFAASDGIVNENLVERFSQEVQ+TEARCFYGFQIAMEN+HSEMYSLLIDTYI+DP
Sbjct: 128 SHVLAFFAASDGIVNENLVERFSQEVQITEARCFYGFQIAMENIHSEMYSLLIDTYIKDP 187
Query: 608 KERDFLFNAVETLPCVKKKADWALQWIASKTATFGERXXXXXXXXXXXXXXXXXXXXWLX 787
KER+FLFNA+ET+PCVKKKADWAL+WI K AT+GER WL
Sbjct: 188 KEREFLFNAIETMPCVKKKADWALRWIGDKEATYGERVVAFAAVEGIFFSGSFASIFWLK 247
Query: 788 KRGLMPGL 811
KRGLMPGL
Sbjct: 248 KRGLMPGL 255
>S40301-1|AAA09577.1| 389|Homo sapiens ribonucleotide reductase R2
subunit protein.
Length = 389
Score = 317 bits (778), Expect = 4e-86
Identities = 154/248 (62%), Positives = 179/248 (72%), Gaps = 7/248 (2%)
Frame = +2
Query: 89 MAPTVDKENLH----SGINGENRVQTKSPMKNS-VLATKNDNLTEEMDLDKNFEEFDP-- 247
+AP D + L G++ ++ T + + VLA+K + + + P
Sbjct: 8 LAPITDPQQLQLSPLKGLSLVDKENTPPALSGTRVLASKTARRIFQEPTEPKTKAAAPGV 67
Query: 248 QKEPLLRENPRRFVIFPIQYPDIWQMYKKAEASFWTVEEVDLSKDLSDWETLKDSERHFI 427
+ EPLLRENPRRFVIFPI+Y DIWQMYKKAEASFWT EEVDLSKD+ WE+LK ER+FI
Sbjct: 68 EDEPLLRENPRRFVIFPIEYHDIWQMYKKAEASFWTAEEVDLSKDIQHWESLKPEERYFI 127
Query: 428 KHVLAFFAASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENVHSEMYSLLIDTYIRDP 607
HVLAFFAASDGIVNENLVERFSQEVQ+TEARCFYGFQIAMEN+HSEMYSLLIDTYI+DP
Sbjct: 128 SHVLAFFAASDGIVNENLVERFSQEVQITEARCFYGFQIAMENIHSEMYSLLIDTYIKDP 187
Query: 608 KERDFLFNAVETLPCVKKKADWALQWIASKTATFGERXXXXXXXXXXXXXXXXXXXXWLX 787
KER+FLFNA+ET+PCVKKKADWAL+WI K AT+GER WL
Sbjct: 188 KEREFLFNAIETMPCVKKKADWALRWIGDKEATYGERVVAFAAVEGIFFSGSFASIFWLK 247
Query: 788 KRGLMPGL 811
KRGLMPGL
Sbjct: 248 KRGLMPGL 255
>BC030154-1|AAH30154.1| 389|Homo sapiens ribonucleotide reductase
M2 polypeptide protein.
Length = 389
Score = 317 bits (778), Expect = 4e-86
Identities = 154/248 (62%), Positives = 179/248 (72%), Gaps = 7/248 (2%)
Frame = +2
Query: 89 MAPTVDKENLH----SGINGENRVQTKSPMKNS-VLATKNDNLTEEMDLDKNFEEFDP-- 247
+AP D + L G++ ++ T + + VLA+K + + + P
Sbjct: 8 LAPITDPQQLQLSPLKGLSLVDKENTPPALSGTRVLASKTARRIFQEPTEPKTKAAAPGV 67
Query: 248 QKEPLLRENPRRFVIFPIQYPDIWQMYKKAEASFWTVEEVDLSKDLSDWETLKDSERHFI 427
+ EPLLRENPRRFVIFPI+Y DIWQMYKKAEASFWT EEVDLSKD+ WE+LK ER+FI
Sbjct: 68 EDEPLLRENPRRFVIFPIEYHDIWQMYKKAEASFWTAEEVDLSKDIQHWESLKPEERYFI 127
Query: 428 KHVLAFFAASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENVHSEMYSLLIDTYIRDP 607
HVLAFFAASDGIVNENLVERFSQEVQ+TEARCFYGFQIAMEN+HSEMYSLLIDTYI+DP
Sbjct: 128 SHVLAFFAASDGIVNENLVERFSQEVQITEARCFYGFQIAMENIHSEMYSLLIDTYIKDP 187
Query: 608 KERDFLFNAVETLPCVKKKADWALQWIASKTATFGERXXXXXXXXXXXXXXXXXXXXWLX 787
KER+FLFNA+ET+PCVKKKADWAL+WI K AT+GER WL
Sbjct: 188 KEREFLFNAIETMPCVKKKADWALRWIGDKEATYGERVVAFAAVEGIFFSGSFASIFWLK 247
Query: 788 KRGLMPGL 811
KRGLMPGL
Sbjct: 248 KRGLMPGL 255
>BC001886-1|AAH01886.1| 389|Homo sapiens ribonucleotide reductase
M2 polypeptide protein.
Length = 389
Score = 317 bits (778), Expect = 4e-86
Identities = 154/248 (62%), Positives = 179/248 (72%), Gaps = 7/248 (2%)
Frame = +2
Query: 89 MAPTVDKENLH----SGINGENRVQTKSPMKNS-VLATKNDNLTEEMDLDKNFEEFDP-- 247
+AP D + L G++ ++ T + + VLA+K + + + P
Sbjct: 8 LAPITDPQQLQLSPLKGLSLVDKENTPPALSGTRVLASKTARRIFQEPTEPKTKAAAPGV 67
Query: 248 QKEPLLRENPRRFVIFPIQYPDIWQMYKKAEASFWTVEEVDLSKDLSDWETLKDSERHFI 427
+ EPLLRENPRRFVIFPI+Y DIWQMYKKAEASFWT EEVDLSKD+ WE+LK ER+FI
Sbjct: 68 EDEPLLRENPRRFVIFPIEYHDIWQMYKKAEASFWTAEEVDLSKDIQHWESLKPEERYFI 127
Query: 428 KHVLAFFAASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENVHSEMYSLLIDTYIRDP 607
HVLAFFAASDGIVNENLVERFSQEVQ+TEARCFYGFQIAMEN+HSEMYSLLIDTYI+DP
Sbjct: 128 SHVLAFFAASDGIVNENLVERFSQEVQITEARCFYGFQIAMENIHSEMYSLLIDTYIKDP 187
Query: 608 KERDFLFNAVETLPCVKKKADWALQWIASKTATFGERXXXXXXXXXXXXXXXXXXXXWLX 787
KER+FLFNA+ET+PCVKKKADWAL+WI K AT+GER WL
Sbjct: 188 KEREFLFNAIETMPCVKKKADWALRWIGDKEATYGERVVAFAAVEGIFFSGSFASIFWLK 247
Query: 788 KRGLMPGL 811
KRGLMPGL
Sbjct: 248 KRGLMPGL 255
>AY032750-1|AAK51163.1| 389|Homo sapiens ribonucleotide reductase
M2 subunit protein.
Length = 389
Score = 317 bits (778), Expect = 4e-86
Identities = 154/248 (62%), Positives = 179/248 (72%), Gaps = 7/248 (2%)
Frame = +2
Query: 89 MAPTVDKENLH----SGINGENRVQTKSPMKNS-VLATKNDNLTEEMDLDKNFEEFDP-- 247
+AP D + L G++ ++ T + + VLA+K + + + P
Sbjct: 8 LAPITDPQQLQLSPLKGLSLVDKENTPPALSGTRVLASKTARRIFQEPTEPKTKAAAPGV 67
Query: 248 QKEPLLRENPRRFVIFPIQYPDIWQMYKKAEASFWTVEEVDLSKDLSDWETLKDSERHFI 427
+ EPLLRENPRRFVIFPI+Y DIWQMYKKAEASFWT EEVDLSKD+ WE+LK ER+FI
Sbjct: 68 EDEPLLRENPRRFVIFPIEYHDIWQMYKKAEASFWTAEEVDLSKDIQHWESLKPEERYFI 127
Query: 428 KHVLAFFAASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENVHSEMYSLLIDTYIRDP 607
HVLAFFAASDGIVNENLVERFSQEVQ+TEARCFYGFQIAMEN+HSEMYSLLIDTYI+DP
Sbjct: 128 SHVLAFFAASDGIVNENLVERFSQEVQITEARCFYGFQIAMENIHSEMYSLLIDTYIKDP 187
Query: 608 KERDFLFNAVETLPCVKKKADWALQWIASKTATFGERXXXXXXXXXXXXXXXXXXXXWLX 787
KER+FLFNA+ET+PCVKKKADWAL+WI K AT+GER WL
Sbjct: 188 KEREFLFNAIETMPCVKKKADWALRWIGDKEATYGERVVAFAAVEGIFFSGSFASIFWLK 247
Query: 788 KRGLMPGL 811
KRGLMPGL
Sbjct: 248 KRGLMPGL 255
>AC104794-2|AAX93099.1| 389|Homo sapiens unknown protein.
Length = 389
Score = 317 bits (778), Expect = 4e-86
Identities = 154/248 (62%), Positives = 179/248 (72%), Gaps = 7/248 (2%)
Frame = +2
Query: 89 MAPTVDKENLH----SGINGENRVQTKSPMKNS-VLATKNDNLTEEMDLDKNFEEFDP-- 247
+AP D + L G++ ++ T + + VLA+K + + + P
Sbjct: 8 LAPITDPQQLQLSPLKGLSLVDKENTPPALSGTRVLASKTARRIFQEPTEPKTKAAAPGV 67
Query: 248 QKEPLLRENPRRFVIFPIQYPDIWQMYKKAEASFWTVEEVDLSKDLSDWETLKDSERHFI 427
+ EPLLRENPRRFVIFPI+Y DIWQMYKKAEASFWT EEVDLSKD+ WE+LK ER+FI
Sbjct: 68 EDEPLLRENPRRFVIFPIEYHDIWQMYKKAEASFWTAEEVDLSKDIQHWESLKPEERYFI 127
Query: 428 KHVLAFFAASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENVHSEMYSLLIDTYIRDP 607
HVLAFFAASDGIVNENLVERFSQEVQ+TEARCFYGFQIAMEN+HSEMYSLLIDTYI+DP
Sbjct: 128 SHVLAFFAASDGIVNENLVERFSQEVQITEARCFYGFQIAMENIHSEMYSLLIDTYIKDP 187
Query: 608 KERDFLFNAVETLPCVKKKADWALQWIASKTATFGERXXXXXXXXXXXXXXXXXXXXWLX 787
KER+FLFNA+ET+PCVKKKADWAL+WI K AT+GER WL
Sbjct: 188 KEREFLFNAIETMPCVKKKADWALRWIGDKEATYGERVVAFAAVEGIFFSGSFASIFWLK 247
Query: 788 KRGLMPGL 811
KRGLMPGL
Sbjct: 248 KRGLMPGL 255
>DQ027001-1|AAY29059.1| 351|Homo sapiens ribonucleotide reductase
M2 B (TP53 inducible) protein.
Length = 351
Score = 301 bits (739), Expect = 2e-81
Identities = 139/202 (68%), Positives = 156/202 (77%)
Frame = +2
Query: 206 EEMDLDKNFEEFDPQKEPLLRENPRRFVIFPIQYPDIWQMYKKAEASFWTVEEVDLSKDL 385
E D N E +EPLLR++ RRFVIFPIQYPDIW+MYK+A+ASFWT EEVDLSKDL
Sbjct: 16 ERSSSDTNESEIKSNEEPLLRKSSRRFVIFPIQYPDIWKMYKQAQASFWTAEEVDLSKDL 75
Query: 386 SDWETLKDSERHFIKHVLAFFAASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENVHS 565
W LK E++FI H+LAFFAASDGIVNENLVERFSQEVQV EARCFYGFQI +ENVHS
Sbjct: 76 PHWNKLKADEKYFISHILAFFAASDGIVNENLVERFSQEVQVPEARCFYGFQILIENVHS 135
Query: 566 EMYSLLIDTYIRDPKERDFLFNAVETLPCVKKKADWALQWIASKTATFGERXXXXXXXXX 745
EMYSLLIDTYIRDPK+R+FLFNA+ET+P VKKKADWAL+WIA + +TFGER
Sbjct: 136 EMYSLLIDTYIRDPKKREFLFNAIETMPYVKKKADWALRWIADRKSTFGERVVAFAAVEG 195
Query: 746 XXXXXXXXXXXWLXKRGLMPGL 811
WL KRGLMPGL
Sbjct: 196 VFFSGSFAAIFWLKKRGLMPGL 217
>BC130628-1|AAI30629.1| 351|Homo sapiens ribonucleotide reductase
M2 B (TP53 inducible) protein.
Length = 351
Score = 301 bits (739), Expect = 2e-81
Identities = 139/202 (68%), Positives = 156/202 (77%)
Frame = +2
Query: 206 EEMDLDKNFEEFDPQKEPLLRENPRRFVIFPIQYPDIWQMYKKAEASFWTVEEVDLSKDL 385
E D N E +EPLLR++ RRFVIFPIQYPDIW+MYK+A+ASFWT EEVDLSKDL
Sbjct: 16 ERSSSDTNESEIKSNEEPLLRKSSRRFVIFPIQYPDIWKMYKQAQASFWTAEEVDLSKDL 75
Query: 386 SDWETLKDSERHFIKHVLAFFAASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENVHS 565
W LK E++FI H+LAFFAASDGIVNENLVERFSQEVQV EARCFYGFQI +ENVHS
Sbjct: 76 PHWNKLKADEKYFISHILAFFAASDGIVNENLVERFSQEVQVPEARCFYGFQILIENVHS 135
Query: 566 EMYSLLIDTYIRDPKERDFLFNAVETLPCVKKKADWALQWIASKTATFGERXXXXXXXXX 745
EMYSLLIDTYIRDPK+R+FLFNA+ET+P VKKKADWAL+WIA + +TFGER
Sbjct: 136 EMYSLLIDTYIRDPKKREFLFNAIETMPYVKKKADWALRWIADRKSTFGERVVAFAAVEG 195
Query: 746 XXXXXXXXXXXWLXKRGLMPGL 811
WL KRGLMPGL
Sbjct: 196 VFFSGSFAAIFWLKKRGLMPGL 217
>BC117496-1|AAI17497.1| 351|Homo sapiens ribonucleotide reductase
M2 B (TP53 inducible) protein.
Length = 351
Score = 301 bits (739), Expect = 2e-81
Identities = 139/202 (68%), Positives = 156/202 (77%)
Frame = +2
Query: 206 EEMDLDKNFEEFDPQKEPLLRENPRRFVIFPIQYPDIWQMYKKAEASFWTVEEVDLSKDL 385
E D N E +EPLLR++ RRFVIFPIQYPDIW+MYK+A+ASFWT EEVDLSKDL
Sbjct: 16 ERSSSDTNESEIKSNEEPLLRKSSRRFVIFPIQYPDIWKMYKQAQASFWTAEEVDLSKDL 75
Query: 386 SDWETLKDSERHFIKHVLAFFAASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENVHS 565
W LK E++FI H+LAFFAASDGIVNENLVERFSQEVQV EARCFYGFQI +ENVHS
Sbjct: 76 PHWNKLKADEKYFISHILAFFAASDGIVNENLVERFSQEVQVPEARCFYGFQILIENVHS 135
Query: 566 EMYSLLIDTYIRDPKERDFLFNAVETLPCVKKKADWALQWIASKTATFGERXXXXXXXXX 745
EMYSLLIDTYIRDPK+R+FLFNA+ET+P VKKKADWAL+WIA + +TFGER
Sbjct: 136 EMYSLLIDTYIRDPKKREFLFNAIETMPYVKKKADWALRWIADRKSTFGERVVAFAAVEG 195
Query: 746 XXXXXXXXXXXWLXKRGLMPGL 811
WL KRGLMPGL
Sbjct: 196 VFFSGSFAAIFWLKKRGLMPGL 217
>BC108261-1|AAI08262.1| 351|Homo sapiens ribonucleotide reductase
M2 B (TP53 inducible) protein.
Length = 351
Score = 301 bits (739), Expect = 2e-81
Identities = 139/202 (68%), Positives = 156/202 (77%)
Frame = +2
Query: 206 EEMDLDKNFEEFDPQKEPLLRENPRRFVIFPIQYPDIWQMYKKAEASFWTVEEVDLSKDL 385
E D N E +EPLLR++ RRFVIFPIQYPDIW+MYK+A+ASFWT EEVDLSKDL
Sbjct: 16 ERSSSDTNESEIKSNEEPLLRKSSRRFVIFPIQYPDIWKMYKQAQASFWTAEEVDLSKDL 75
Query: 386 SDWETLKDSERHFIKHVLAFFAASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENVHS 565
W LK E++FI H+LAFFAASDGIVNENLVERFSQEVQV EARCFYGFQI +ENVHS
Sbjct: 76 PHWNKLKADEKYFISHILAFFAASDGIVNENLVERFSQEVQVPEARCFYGFQILIENVHS 135
Query: 566 EMYSLLIDTYIRDPKERDFLFNAVETLPCVKKKADWALQWIASKTATFGERXXXXXXXXX 745
EMYSLLIDTYIRDPK+R+FLFNA+ET+P VKKKADWAL+WIA + +TFGER
Sbjct: 136 EMYSLLIDTYIRDPKKREFLFNAIETMPYVKKKADWALRWIADRKSTFGERVVAFAAVEG 195
Query: 746 XXXXXXXXXXXWLXKRGLMPGL 811
WL KRGLMPGL
Sbjct: 196 VFFSGSFAAIFWLKKRGLMPGL 217
>AK001965-1|BAA92005.1| 351|Homo sapiens protein ( Homo sapiens
cDNA FLJ11103 fis, clone PLACE1005656, highly similar to
RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE M2 CHAIN (EC
1.17.4.1). ).
Length = 351
Score = 301 bits (739), Expect = 2e-81
Identities = 139/202 (68%), Positives = 156/202 (77%)
Frame = +2
Query: 206 EEMDLDKNFEEFDPQKEPLLRENPRRFVIFPIQYPDIWQMYKKAEASFWTVEEVDLSKDL 385
E D N E +EPLLR++ RRFVIFPIQYPDIW+MYK+A+ASFWT EEVDLSKDL
Sbjct: 16 ERSSSDTNESEIKSNEEPLLRKSSRRFVIFPIQYPDIWKMYKQAQASFWTAEEVDLSKDL 75
Query: 386 SDWETLKDSERHFIKHVLAFFAASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENVHS 565
W LK E++FI H+LAFFAASDGIVNENLVERFSQEVQV EARCFYGFQI +ENVHS
Sbjct: 76 PHWNKLKADEKYFISHILAFFAASDGIVNENLVERFSQEVQVPEARCFYGFQILIENVHS 135
Query: 566 EMYSLLIDTYIRDPKERDFLFNAVETLPCVKKKADWALQWIASKTATFGERXXXXXXXXX 745
EMYSLLIDTYIRDPK+R+FLFNA+ET+P VKKKADWAL+WIA + +TFGER
Sbjct: 136 EMYSLLIDTYIRDPKKREFLFNAIETMPYVKKKADWALRWIADRKSTFGERVVAFAAVEG 195
Query: 746 XXXXXXXXXXXWLXKRGLMPGL 811
WL KRGLMPGL
Sbjct: 196 VFFSGSFAAIFWLKKRGLMPGL 217
>AB166671-1|BAD12267.1| 351|Homo sapiens p53-inducible
ribonucleotide reductase small subunit 2 protein.
Length = 351
Score = 301 bits (739), Expect = 2e-81
Identities = 139/202 (68%), Positives = 156/202 (77%)
Frame = +2
Query: 206 EEMDLDKNFEEFDPQKEPLLRENPRRFVIFPIQYPDIWQMYKKAEASFWTVEEVDLSKDL 385
E D N E +EPLLR++ RRFVIFPIQYPDIW+MYK+A+ASFWT EEVDLSKDL
Sbjct: 16 ERSSSDTNESEIKSNEEPLLRKSSRRFVIFPIQYPDIWKMYKQAQASFWTAEEVDLSKDL 75
Query: 386 SDWETLKDSERHFIKHVLAFFAASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENVHS 565
W LK E++FI H+LAFFAASDGIVNENLVERFSQEVQV EARCFYGFQI +ENVHS
Sbjct: 76 PHWNKLKADEKYFISHILAFFAASDGIVNENLVERFSQEVQVPEARCFYGFQILIENVHS 135
Query: 566 EMYSLLIDTYIRDPKERDFLFNAVETLPCVKKKADWALQWIASKTATFGERXXXXXXXXX 745
EMYSLLIDTYIRDPK+R+FLFNA+ET+P VKKKADWAL+WIA + +TFGER
Sbjct: 136 EMYSLLIDTYIRDPKKREFLFNAIETMPYVKKKADWALRWIADRKSTFGERVVAFAAVEG 195
Query: 746 XXXXXXXXXXXWLXKRGLMPGL 811
WL KRGLMPGL
Sbjct: 196 VFFSGSFAAIFWLKKRGLMPGL 217
>AB036532-1|BAA92493.1| 351|Homo sapiens ribonucleotide reductase
protein.
Length = 351
Score = 301 bits (739), Expect = 2e-81
Identities = 139/202 (68%), Positives = 156/202 (77%)
Frame = +2
Query: 206 EEMDLDKNFEEFDPQKEPLLRENPRRFVIFPIQYPDIWQMYKKAEASFWTVEEVDLSKDL 385
E D N E +EPLLR++ RRFVIFPIQYPDIW+MYK+A+ASFWT EEVDLSKDL
Sbjct: 16 ERSSSDTNESEIKSNEEPLLRKSSRRFVIFPIQYPDIWKMYKQAQASFWTAEEVDLSKDL 75
Query: 386 SDWETLKDSERHFIKHVLAFFAASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENVHS 565
W LK E++FI H+LAFFAASDGIVNENLVERFSQEVQV EARCFYGFQI +ENVHS
Sbjct: 76 PHWNKLKADEKYFISHILAFFAASDGIVNENLVERFSQEVQVPEARCFYGFQILIENVHS 135
Query: 566 EMYSLLIDTYIRDPKERDFLFNAVETLPCVKKKADWALQWIASKTATFGERXXXXXXXXX 745
EMYSLLIDTYIRDPK+R+FLFNA+ET+P VKKKADWAL+WIA + +TFGER
Sbjct: 136 EMYSLLIDTYIRDPKKREFLFNAIETMPYVKKKADWALRWIADRKSTFGERVVAFAAVEG 195
Query: 746 XXXXXXXXXXXWLXKRGLMPGL 811
WL KRGLMPGL
Sbjct: 196 VFFSGSFAAIFWLKKRGLMPGL 217
>AB036063-1|BAA92434.1| 351|Homo sapiens ribonucleotide reductase
protein.
Length = 351
Score = 301 bits (739), Expect = 2e-81
Identities = 139/202 (68%), Positives = 156/202 (77%)
Frame = +2
Query: 206 EEMDLDKNFEEFDPQKEPLLRENPRRFVIFPIQYPDIWQMYKKAEASFWTVEEVDLSKDL 385
E D N E +EPLLR++ RRFVIFPIQYPDIW+MYK+A+ASFWT EEVDLSKDL
Sbjct: 16 ERSSSDTNESEIKSNEEPLLRKSSRRFVIFPIQYPDIWKMYKQAQASFWTAEEVDLSKDL 75
Query: 386 SDWETLKDSERHFIKHVLAFFAASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENVHS 565
W LK E++FI H+LAFFAASDGIVNENLVERFSQEVQV EARCFYGFQI +ENVHS
Sbjct: 76 PHWNKLKADEKYFISHILAFFAASDGIVNENLVERFSQEVQVPEARCFYGFQILIENVHS 135
Query: 566 EMYSLLIDTYIRDPKERDFLFNAVETLPCVKKKADWALQWIASKTATFGERXXXXXXXXX 745
EMYSLLIDTYIRDPK+R+FLFNA+ET+P VKKKADWAL+WIA + +TFGER
Sbjct: 136 EMYSLLIDTYIRDPKKREFLFNAIETMPYVKKKADWALRWIADRKSTFGERVVAFAAVEG 195
Query: 746 XXXXXXXXXXXWLXKRGLMPGL 811
WL KRGLMPGL
Sbjct: 196 VFFSGSFAAIFWLKKRGLMPGL 217
>AB163437-1|BAD11774.1| 299|Homo sapiens p53-inducible
ribonucleotide reductase small subunit 2 long form
protein.
Length = 299
Score = 231 bits (564), Expect = 3e-60
Identities = 108/161 (67%), Positives = 123/161 (76%)
Frame = +2
Query: 329 KKAEASFWTVEEVDLSKDLSDWETLKDSERHFIKHVLAFFAASDGIVNENLVERFSQEVQ 508
++ EA+ +EVDLSKDL W LK E++FI H+LAFFAASDGIVNENLVERFSQEVQ
Sbjct: 5 ERPEAAGLDQDEVDLSKDLPHWNKLKADEKYFISHILAFFAASDGIVNENLVERFSQEVQ 64
Query: 509 VTEARCFYGFQIAMENVHSEMYSLLIDTYIRDPKERDFLFNAVETLPCVKKKADWALQWI 688
V EARCFYGFQI +ENVHSEMYSLLIDTYIRDPK+R+FLFNA+ET+P VKKKADWAL+WI
Sbjct: 65 VPEARCFYGFQILIENVHSEMYSLLIDTYIRDPKKREFLFNAIETMPYVKKKADWALRWI 124
Query: 689 ASKTATFGERXXXXXXXXXXXXXXXXXXXXWLXKRGLMPGL 811
A + +TFGER WL KRGLMPGL
Sbjct: 125 ADRKSTFGERVVAFAAVEGVFFSGSFAAIFWLKKRGLMPGL 165
>BC042468-1|AAH42468.1| 285|Homo sapiens Similar to ribonucleotide
reductase M2 polypeptide protein.
Length = 285
Score = 230 bits (563), Expect = 4e-60
Identities = 107/151 (70%), Positives = 118/151 (78%)
Frame = +2
Query: 359 EEVDLSKDLSDWETLKDSERHFIKHVLAFFAASDGIVNENLVERFSQEVQVTEARCFYGF 538
EEVDLSKDL W LK E++FI H+LAFFAASDGIVNENLVERFSQEVQV EARCFYGF
Sbjct: 1 EEVDLSKDLPHWNKLKADEKYFISHILAFFAASDGIVNENLVERFSQEVQVPEARCFYGF 60
Query: 539 QIAMENVHSEMYSLLIDTYIRDPKERDFLFNAVETLPCVKKKADWALQWIASKTATFGER 718
QI +ENVHSEMYSLLIDTYIRDPK+R+FLFNA+ET+P VKKKADWAL+WIA + +TFGER
Sbjct: 61 QILIENVHSEMYSLLIDTYIRDPKKREFLFNAIETMPYVKKKADWALRWIADRKSTFGER 120
Query: 719 XXXXXXXXXXXXXXXXXXXXWLXKRGLMPGL 811
WL KRGLMPGL
Sbjct: 121 VVAFAAVEGVFFSGSFAAIFWLKKRGLMPGL 151
>BC068260-1|AAH68260.1| 601|Homo sapiens PRODH protein protein.
Length = 601
Score = 34.3 bits (75), Expect = 0.53
Identities = 24/89 (26%), Positives = 42/89 (47%), Gaps = 3/89 (3%)
Frame = +2
Query: 332 KAEASFW-TVEEVDLS--KDLSDWETLKDSERHFIKHVLAFFAASDGIVNENLVERFSQE 502
+AE W T E + +S DL DW +L DS KH++ A + + E+L+ RF++E
Sbjct: 295 RAEIEDWFTAETLGVSGTMDLLDWSSLIDSRTKLSKHLVVPNAQTGQL--EHLLSRFTEE 352
Query: 503 VQVTEARCFYGFQIAMENVHSEMYSLLID 589
++ R + + L++D
Sbjct: 353 EELQMTRMLQRMDVLAKKATEMGVRLMVD 381
>U82381-1|AAB88789.1| 516|Homo sapiens proline
dehydrogenase/proline oxidase protein.
Length = 516
Score = 33.1 bits (72), Expect = 1.2
Identities = 24/89 (26%), Positives = 41/89 (46%), Gaps = 3/89 (3%)
Frame = +2
Query: 332 KAEASFW-TVEEVDLS--KDLSDWETLKDSERHFIKHVLAFFAASDGIVNENLVERFSQE 502
+AE W T E + +S DL DW +L DS KH++ A + + E L+ RF++E
Sbjct: 210 RAEIEDWFTAETLGVSGTMDLLDWSSLIDSRTKLSKHLVVPNAQTGQL--EPLLSRFTEE 267
Query: 503 VQVTEARCFYGFQIAMENVHSEMYSLLID 589
++ R + + L++D
Sbjct: 268 EELQMTRMLQRMDVLAKKATEMGVRLMVD 296
>BC121809-1|AAI21810.1| 492|Homo sapiens PRODH protein protein.
Length = 492
Score = 33.1 bits (72), Expect = 1.2
Identities = 24/89 (26%), Positives = 41/89 (46%), Gaps = 3/89 (3%)
Frame = +2
Query: 332 KAEASFW-TVEEVDLS--KDLSDWETLKDSERHFIKHVLAFFAASDGIVNENLVERFSQE 502
+AE W T E + +S DL DW +L DS KH++ A + + E L+ RF++E
Sbjct: 186 RAEIEDWFTAETLGVSGTMDLLDWSSLIDSRTKLSKHLVVPNAQTGQL--EPLLSRFTEE 243
Query: 503 VQVTEARCFYGFQIAMENVHSEMYSLLID 589
++ R + + L++D
Sbjct: 244 EELQMTRMLQRMDVLAKKATEMGVRLMVD 272
>BC118597-1|AAI18598.1| 492|Homo sapiens PRODH protein protein.
Length = 492
Score = 33.1 bits (72), Expect = 1.2
Identities = 24/89 (26%), Positives = 41/89 (46%), Gaps = 3/89 (3%)
Frame = +2
Query: 332 KAEASFW-TVEEVDLS--KDLSDWETLKDSERHFIKHVLAFFAASDGIVNENLVERFSQE 502
+AE W T E + +S DL DW +L DS KH++ A + + E L+ RF++E
Sbjct: 186 RAEIEDWFTAETLGVSGTMDLLDWSSLIDSRTKLSKHLVVPNAQTGQL--EPLLSRFTEE 243
Query: 503 VQVTEARCFYGFQIAMENVHSEMYSLLID 589
++ R + + L++D
Sbjct: 244 EELQMTRMLQRMDVLAKKATEMGVRLMVD 272
>BC094736-1|AAH94736.1| 544|Homo sapiens PRODH protein protein.
Length = 544
Score = 33.1 bits (72), Expect = 1.2
Identities = 24/89 (26%), Positives = 41/89 (46%), Gaps = 3/89 (3%)
Frame = +2
Query: 332 KAEASFW-TVEEVDLS--KDLSDWETLKDSERHFIKHVLAFFAASDGIVNENLVERFSQE 502
+AE W T E + +S DL DW +L DS KH++ A + + E L+ RF++E
Sbjct: 238 RAEIEDWFTAETLGVSGTMDLLDWSSLIDSRTKLSKHLVVPNAQTGQL--EPLLSRFTEE 295
Query: 503 VQVTEARCFYGFQIAMENVHSEMYSLLID 589
++ R + + L++D
Sbjct: 296 EELQMTRMLQRMDVLAKKATEMGVRLMVD 324
>AF120278-1|AAD24775.1| 516|Homo sapiens proline dehydrogenase
protein.
Length = 516
Score = 33.1 bits (72), Expect = 1.2
Identities = 24/89 (26%), Positives = 41/89 (46%), Gaps = 3/89 (3%)
Frame = +2
Query: 332 KAEASFW-TVEEVDLS--KDLSDWETLKDSERHFIKHVLAFFAASDGIVNENLVERFSQE 502
+AE W T E + +S DL DW +L DS KH++ A + + E L+ RF++E
Sbjct: 210 RAEIEDWFTAETLGVSGTMDLLDWSSLIDSRTKLSKHLVVPNAQTGQL--EPLLSRFTEE 267
Query: 503 VQVTEARCFYGFQIAMENVHSEMYSLLID 589
++ R + + L++D
Sbjct: 268 EELQMTRMLQRMDVLAKKATEMGVRLMVD 296
>BC028932-1|AAH28932.1| 172|Homo sapiens Similar to ribonucleotide
reductase protein r2 class I protein.
Length = 172
Score = 32.7 bits (71), Expect = 1.6
Identities = 15/37 (40%), Positives = 16/37 (43%)
Frame = +2
Query: 701 ATFGERXXXXXXXXXXXXXXXXXXXXWLXKRGLMPGL 811
AT+GER WL KRGLMPGL
Sbjct: 2 ATYGERVVAFAAVEGIFFSGSFASIFWLKKRGLMPGL 38
>U79754-1|AAF21464.1| 600|Homo sapiens proline oxidase 2 protein.
Length = 600
Score = 30.3 bits (65), Expect = 8.7
Identities = 23/89 (25%), Positives = 40/89 (44%), Gaps = 3/89 (3%)
Frame = +2
Query: 332 KAEASFW-TVEEVDLS--KDLSDWETLKDSERHFIKHVLAFFAASDGIVNENLVERFSQE 502
+AE W T E + +S DL DW +L DS KH++ A + + E L+ F++E
Sbjct: 294 RAEIEDWFTAETLGVSGTMDLLDWSSLIDSRTKLSKHLVVPNAQTGQL--EPLLSGFTEE 351
Query: 503 VQVTEARCFYGFQIAMENVHSEMYSLLID 589
++ R + + L++D
Sbjct: 352 EELQMTRMLQRMDVLAKKATEMGVRLMVD 380
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 111,665,258
Number of Sequences: 237096
Number of extensions: 2285474
Number of successful extensions: 4268
Number of sequences better than 10.0: 24
Number of HSP's better than 10.0 without gapping: 4031
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4268
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 10092110758
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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