Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P16_F_K06
(776 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_P11177 Cluster: Pyruvate dehydrogenase E1 component sub... 295 8e-79
UniRef50_Q6N5V4 Cluster: Pyruvate dehydrogenase E1 beta subunit;... 245 1e-63
UniRef50_Q4UKQ7 Cluster: Pyruvate dehydrogenase E1 component sub... 242 8e-63
UniRef50_O66113 Cluster: Pyruvate dehydrogenase E1 component sub... 232 6e-60
UniRef50_Q1VWM3 Cluster: Pyruvate dehydrogenase E1 component, be... 198 1e-49
UniRef50_Q74AE0 Cluster: Dehydrogenase complex, E1 component, be... 174 2e-42
UniRef50_A7CXZ3 Cluster: Transketolase central region; n=1; Opit... 167 2e-40
UniRef50_Q8DMB7 Cluster: Pyruvate dehydrogenase E1 component bet... 165 1e-39
UniRef50_A6Q3I5 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 164 3e-39
UniRef50_Q98FT4 Cluster: Acetoin dehydrogenase (TPP-dependent) b... 161 1e-38
UniRef50_A3VIE8 Cluster: Acetoin dehydrogenase (TPP-dependent) b... 160 3e-38
UniRef50_A5UU14 Cluster: Transketolase, central region; n=3; Chl... 160 4e-38
UniRef50_Q8IML6 Cluster: CG11876-PB, isoform B; n=2; melanogaste... 158 1e-37
UniRef50_A6UDY4 Cluster: Transketolase central region; n=1; Sino... 151 2e-35
UniRef50_P37941 Cluster: 2-oxoisovalerate dehydrogenase subunit ... 151 2e-35
UniRef50_Q03KN0 Cluster: Pyruvate dehydrogenase (E1) component, ... 150 4e-35
UniRef50_Q32RM2 Cluster: Pyruvate dehydrogenase E1 component sub... 150 4e-35
UniRef50_A5V539 Cluster: Transketolase, central region; n=4; Bac... 147 2e-34
UniRef50_P96103 Cluster: Pyruvate dehydrogenase complex E1 beta ... 146 5e-34
UniRef50_A1SN85 Cluster: Transketolase, central region; n=4; cel... 145 9e-34
UniRef50_A0LFE7 Cluster: Transketolase domain protein; n=1; Synt... 145 9e-34
UniRef50_A5V352 Cluster: Transketolase, central region; n=1; Sph... 144 3e-33
UniRef50_Q3WCG4 Cluster: Transketolase, central region:Transketo... 143 4e-33
UniRef50_Q5L234 Cluster: Thiamine pyrophosphate-dependent dehydr... 142 7e-33
UniRef50_A0LTR0 Cluster: Transketolase, central region; n=2; Act... 141 2e-32
UniRef50_P35488 Cluster: Pyruvate dehydrogenase E1 component sub... 141 2e-32
UniRef50_Q72GU2 Cluster: 2-oxoisovalerate dehydrogenase subunit ... 141 2e-32
UniRef50_Q9Z9E8 Cluster: (Pyruvate) Oxoisovalerate Dehydrogenase... 140 5e-32
UniRef50_A0Z5N8 Cluster: Acetoin dehydrogenase E1 component, bet... 140 5e-32
UniRef50_Q1AZ53 Cluster: Transketolase, central region; n=1; Rub... 139 6e-32
UniRef50_Q28MR4 Cluster: Dehydrogenase E1 component; n=8; Bacter... 138 1e-31
UniRef50_A0UXT4 Cluster: Transketolase-like; n=1; Clostridium ce... 136 6e-31
UniRef50_Q5UWH0 Cluster: Pyruvate dehydrogenase; n=55; cellular ... 136 8e-31
UniRef50_Q5VGY3 Cluster: Pyruvate dehydrogenase beta subunit; n=... 135 1e-30
UniRef50_Q5HKL9 Cluster: Acetoin dehydrogenase, E1 component, be... 134 2e-30
UniRef50_Q9KG98 Cluster: Pyruvate dehydrogenase E1 (Lipoamide) b... 134 2e-30
UniRef50_Q97YF5 Cluster: Pyruvate dehydrogenase, beta subunit (L... 134 2e-30
UniRef50_Q0LRY7 Cluster: Dehydrogenase, E1 component:Transketola... 134 3e-30
UniRef50_A0H598 Cluster: Transketolase, central region; n=2; Chl... 132 7e-30
UniRef50_Q0MX86 Cluster: Pyruvate dehydrogenase beta-subunit; n=... 132 9e-30
UniRef50_A5UVZ0 Cluster: Transketolase, central region; n=5; Bac... 132 9e-30
UniRef50_A7BPK5 Cluster: Pyruvate dehydrogenase, E1 component, b... 132 1e-29
UniRef50_O34591 Cluster: Acetoin:2,6-dichlorophenolindophenol ox... 129 9e-29
UniRef50_Q0W152 Cluster: Pyruvate dehydrogenase complex E1, tran... 127 4e-28
UniRef50_Q9I1M1 Cluster: 2-oxoisovalerate dehydrogenase subunit ... 124 3e-27
UniRef50_Q1ARM1 Cluster: Transketolase-like protein; n=2; Bacter... 122 8e-27
UniRef50_A0HHH4 Cluster: Transketolase, central region; n=2; Bac... 122 1e-26
UniRef50_Q4DEQ0 Cluster: 2-oxoisovalerate dehydrogenase beta sub... 121 2e-26
UniRef50_Q479Q1 Cluster: Transketolase, central region:Transketo... 120 3e-26
UniRef50_P75391 Cluster: Pyruvate dehydrogenase E1 component sub... 119 9e-26
UniRef50_A1RJV5 Cluster: Transketolase, central region; n=18; ce... 118 2e-25
UniRef50_A5V556 Cluster: Transketolase domain protein; n=1; Sphi... 118 2e-25
UniRef50_A0JY24 Cluster: Transketolase, central region; n=2; cel... 118 2e-25
UniRef50_P0A0A3 Cluster: Pyruvate dehydrogenase E1 component sub... 118 2e-25
UniRef50_Q023C4 Cluster: Pyruvate dehydrogenase; n=1; Solibacter... 117 4e-25
UniRef50_P21882 Cluster: Pyruvate dehydrogenase E1 component sub... 117 4e-25
UniRef50_UPI000155C0B5 Cluster: PREDICTED: similar to pyruvate d... 115 1e-24
UniRef50_A4XF90 Cluster: Transketolase domain protein; n=1; Novo... 111 1e-23
UniRef50_Q020J5 Cluster: Dehydrogenase, E1 component; n=1; Solib... 111 2e-23
UniRef50_Q83X27 Cluster: Probable pyruvate dehydrogenase beta-su... 110 4e-23
UniRef50_A7CXF2 Cluster: Transketolase central region; n=1; Opit... 109 8e-23
UniRef50_A0M1U4 Cluster: 2-oxoisovalerate dehydrogenase E1 compo... 109 8e-23
UniRef50_Q83DL8 Cluster: Dehydrogenase, E1 component, beta subun... 108 2e-22
UniRef50_A4L2Q6 Cluster: E1 component beta subunit; n=16; Bacill... 107 2e-22
UniRef50_A4XHV5 Cluster: Transketolase, central region; n=3; Bac... 107 3e-22
UniRef50_Q6ABX8 Cluster: Pyruvate dehydrogenase E1 component sub... 105 2e-21
UniRef50_P21953 Cluster: 2-oxoisovalerate dehydrogenase subunit ... 105 2e-21
UniRef50_Q319T3 Cluster: Pyruvate dehydrogenase; n=1; Prochloroc... 104 2e-21
UniRef50_Q5BSL1 Cluster: SJCHGC03862 protein; n=1; Schistosoma j... 104 2e-21
UniRef50_Q1IQR3 Cluster: Dehydrogenase, E1 component; n=1; Acido... 104 3e-21
UniRef50_A7EW39 Cluster: Pyruvate dehydrogenase E1 component bet... 103 5e-21
UniRef50_A1G854 Cluster: Transketolase, central region; n=3; Act... 101 2e-20
UniRef50_Q2BFQ9 Cluster: Putative uncharacterized protein; n=1; ... 100 5e-20
UniRef50_A5ACP6 Cluster: Putative uncharacterized protein; n=1; ... 98 2e-19
UniRef50_A2TU24 Cluster: (Pyruvate) Oxoisovalerate Dehydrogenase... 98 2e-19
UniRef50_A3BGZ8 Cluster: Putative uncharacterized protein; n=2; ... 95 2e-18
UniRef50_Q7N3C2 Cluster: Similar to 3-methyl-2-oxobutanoate dehy... 94 3e-18
UniRef50_A3SJ75 Cluster: 2-oxoisovalerate dehydrogenase beta sub... 93 5e-18
UniRef50_Q8YDW3 Cluster: 2-OXOISOVALERATE DEHYDROGENASE BETA SUB... 86 8e-16
UniRef50_Q9K3H1 Cluster: Putative pyruvate dehydrogenase beta su... 85 2e-15
UniRef50_Q8YDG0 Cluster: 2-OXOISOVALERATE DEHYDROGENASE BETA SUB... 85 2e-15
UniRef50_Q00TN9 Cluster: Pyruvate dehydrogenase E1 component bet... 83 6e-15
UniRef50_Q2WB98 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 83 8e-15
UniRef50_A6W004 Cluster: Transketolase domain protein; n=6; Prot... 82 2e-14
UniRef50_A6FZ18 Cluster: 2-oxoisovalerate dehydrogenase, E1 comp... 78 2e-13
UniRef50_Q11G19 Cluster: Transketolase-like; n=2; Proteobacteria... 73 6e-12
UniRef50_UPI000038D520 Cluster: COG0022: Pyruvate/2-oxoglutarate... 72 1e-11
UniRef50_Q7N5R1 Cluster: Similar to 3-methyl-2-oxobutanoate dehy... 71 2e-11
UniRef50_A7P4X0 Cluster: Chromosome chr4 scaffold_6, whole genom... 71 2e-11
UniRef50_A4F1Y5 Cluster: Branched-chain alpha-keto acid decarbox... 71 4e-11
UniRef50_Q748I3 Cluster: Dehydrogenase, E1 component, alpha and ... 66 9e-10
UniRef50_Q8AB00 Cluster: 2-oxoisovalerate dehydrogenase beta sub... 64 5e-09
UniRef50_A3PXW7 Cluster: Transketolase domain protein; n=4; Myco... 64 5e-09
UniRef50_Q50851 Cluster: Branched-chain keto acid dehydrogenase ... 63 7e-09
UniRef50_Q5AT21 Cluster: Putative uncharacterized protein; n=1; ... 63 9e-09
UniRef50_A1GCL6 Cluster: Transketolase-like; n=2; Salinispora|Re... 62 1e-08
UniRef50_A4BZ87 Cluster: Acetoin dehydrogenase (TPP-dependent) b... 61 3e-08
UniRef50_Q7V0M6 Cluster: Dehydrogenase E1 component beta subunit... 58 3e-07
UniRef50_Q7NLM8 Cluster: Gll1094 protein; n=1; Gloeobacter viola... 56 7e-07
UniRef50_Q5LVW0 Cluster: Dehydrogenase/transketolase family prot... 56 7e-07
UniRef50_A2C5U9 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 55 2e-06
UniRef50_UPI0000D9ADA1 Cluster: PREDICTED: similar to 2-oxoisova... 46 0.001
UniRef50_UPI0000383A75 Cluster: COG0508: Pyruvate/2-oxoglutarate... 38 0.21
UniRef50_UPI00015970BB Cluster: GabT1; n=1; Bacillus amyloliquef... 36 1.1
UniRef50_A6GB58 Cluster: Transketolase; n=1; Plesiocystis pacifi... 36 1.1
UniRef50_Q2IY37 Cluster: Tyrosinase; n=1; Rhodopseudomonas palus... 34 3.4
UniRef50_A6LE04 Cluster: Putative uncharacterized protein; n=2; ... 34 3.4
UniRef50_Q8EVJ3 Cluster: Transposase for IS1202-like insertion s... 34 4.6
UniRef50_Q2IQQ3 Cluster: Putative uncharacterized protein precur... 34 4.6
UniRef50_A1AY54 Cluster: Regulatory protein, LuxR; n=1; Paracocc... 34 4.6
UniRef50_Q4SZE5 Cluster: Chromosome undetermined SCAF11680, whol... 33 6.0
UniRef50_Q4SI33 Cluster: Chromosome 5 SCAF14581, whole genome sh... 33 8.0
UniRef50_Q89XT5 Cluster: Glyoxalase II; n=16; Alphaproteobacteri... 33 8.0
UniRef50_Q47C78 Cluster: Isochorismate synthase; n=1; Dechloromo... 33 8.0
UniRef50_Q2I773 Cluster: PlaT6; n=9; Actinomycetales|Rep: PlaT6 ... 33 8.0
UniRef50_A7SMP5 Cluster: Predicted protein; n=1; Nematostella ve... 33 8.0
UniRef50_A7AWY3 Cluster: Putative uncharacterized protein; n=1; ... 33 8.0
>UniRef50_P11177 Cluster: Pyruvate dehydrogenase E1 component
subunit beta, mitochondrial precursor; n=144; cellular
organisms|Rep: Pyruvate dehydrogenase E1 component
subunit beta, mitochondrial precursor - Homo sapiens
(Human)
Length = 359
Score = 295 bits (724), Expect = 8e-79
Identities = 132/183 (72%), Positives = 156/183 (85%)
Frame = +1
Query: 223 ALASKPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTP 402
A A+ VTVRDA+NQ +DEE+ERDEKVF+LGEEVAQYDGAYKV+RGLWKKYGDKR+IDTP
Sbjct: 27 APAALQVTVRDAINQGMDEELERDEKVFLLGEEVAQYDGAYKVSRGLWKKYGDKRIIDTP 86
Query: 403 ITEXXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRG 582
I+E L+PICEFMTFNFSMQAID +INSAAKT+YMS G PVPIVFRG
Sbjct: 87 ISEMGFAGIAVGAAMAGLRPICEFMTFNFSMQAIDQVINSAAKTYYMSGGLQPVPIVFRG 146
Query: 583 PNGAASSVAAQHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVMLEDEIMY 762
PNGA++ VAAQHSQCF AWY HCPGLKV+ P+++EDAKGL+K+AIRD +PVV+LE+E+MY
Sbjct: 147 PNGASAGVAAQHSQCFAAWYGHCPGLKVVSPWNSEDAKGLIKSAIRDNNPVVVLENELMY 206
Query: 763 GIP 771
G+P
Sbjct: 207 GVP 209
>UniRef50_Q6N5V4 Cluster: Pyruvate dehydrogenase E1 beta subunit;
n=24; cellular organisms|Rep: Pyruvate dehydrogenase E1
beta subunit - Rhodopseudomonas palustris
Length = 469
Score = 245 bits (599), Expect = 1e-63
Identities = 117/175 (66%), Positives = 136/175 (77%)
Frame = +1
Query: 241 VTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXX 420
VT+R+AL A+ EEM RD VFV+GEEVA+Y GAYKVT+GL +++GD+RVIDTPITE
Sbjct: 147 VTIREALRDAMAEEMRRDPDVFVMGEEVAEYQGAYKVTQGLLQEFGDRRVIDTPITEHGF 206
Query: 421 XXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAAS 600
LKPI EFMTFNF+MQAID IINSAAKT YMS G + IVFRGPNGAAS
Sbjct: 207 AGVGVGAGFAGLKPIVEFMTFNFAMQAIDQIINSAAKTLYMSGGQLGCSIVFRGPNGAAS 266
Query: 601 SVAAQHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVMLEDEIMYG 765
VAAQHSQ + AWY+ PGLKV+ PYSA DAKGLLKAAIRDP+PV+ LE E++YG
Sbjct: 267 RVAAQHSQDYSAWYAQIPGLKVVAPYSAADAKGLLKAAIRDPNPVIFLEHEMLYG 321
>UniRef50_Q4UKQ7 Cluster: Pyruvate dehydrogenase E1 component
subunit beta; n=35; cellular organisms|Rep: Pyruvate
dehydrogenase E1 component subunit beta - Rickettsia
felis (Rickettsia azadi)
Length = 326
Score = 242 bits (592), Expect = 8e-63
Identities = 115/175 (65%), Positives = 135/175 (77%)
Frame = +1
Query: 241 VTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXX 420
+TVR+AL A+ EEM RD+KVFV+GEEVA+Y GAYKVT+GL +++G KRVIDTPITE
Sbjct: 3 ITVREALRDAMQEEMIRDDKVFVMGEEVAEYQGAYKVTQGLLEQFGPKRVIDTPITEYGF 62
Query: 421 XXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAAS 600
L+PI EFMTFNF+MQA DHI+NSAAKT YMS G PIVFRGPNGAAS
Sbjct: 63 AGLAVGAAFAGLRPIVEFMTFNFAMQAFDHIVNSAAKTHYMSGGQAKCPIVFRGPNGAAS 122
Query: 601 SVAAQHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVMLEDEIMYG 765
VAAQHSQ + A YSH PGLKV+ PYSAED KGL+ AIRD +PV+ LE+EI+YG
Sbjct: 123 RVAAQHSQNYTACYSHVPGLKVVAPYSAEDHKGLMLTAIRDDNPVIFLENEILYG 177
>UniRef50_O66113 Cluster: Pyruvate dehydrogenase E1 component
subunit beta; n=99; Bacteria|Rep: Pyruvate dehydrogenase
E1 component subunit beta - Zymomonas mobilis
Length = 462
Score = 232 bits (568), Expect = 6e-60
Identities = 111/174 (63%), Positives = 131/174 (75%)
Frame = +1
Query: 244 TVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXX 423
T+R+AL A+ EEM RD++VFV+GEEVA+Y GAYKVT+GL +++G +RV+DTPI+E
Sbjct: 140 TLREALRDAMAEEMRRDDRVFVMGEEVAEYQGAYKVTQGLLQEFGARRVVDTPISEYGFS 199
Query: 424 XXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASS 603
L+P+ EFMT NFSMQAIDHIINSAAKT YMS G V PIVFRGPNGAA
Sbjct: 200 GIGVGAAMEGLRPVIEFMTMNFSMQAIDHIINSAAKTHYMSGGQVRCPIVFRGPNGAAPR 259
Query: 604 VAAQHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVMLEDEIMYG 765
V AQH+Q FG WY+ PGL VL PY A DAKGLLKAAIR DPVV LE E++YG
Sbjct: 260 VGAQHTQNFGPWYAAVPGLVVLAPYDAIDAKGLLKAAIRSDDPVVFLECELLYG 313
>UniRef50_Q1VWM3 Cluster: Pyruvate dehydrogenase E1 component, beta
subunit; n=1; Psychroflexus torquis ATCC 700755|Rep:
Pyruvate dehydrogenase E1 component, beta subunit -
Psychroflexus torquis ATCC 700755
Length = 325
Score = 198 bits (483), Expect = 1e-49
Identities = 90/177 (50%), Positives = 125/177 (70%)
Frame = +1
Query: 235 KPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEX 414
+ + R+A+ +A+ EEM DE ++++GEEVA+Y+GAYK ++G+ ++G+KRVIDTPI+E
Sbjct: 2 RTIQFREAIVEAMSEEMRADETIYLMGEEVAEYNGAYKASKGMLDEFGEKRVIDTPISEL 61
Query: 415 XXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGA 594
+PI EFMTFNFS+ ID IIN+AAK MS G +PIVFRGP G+
Sbjct: 62 GFTGIGIGSAMNGNRPIIEFMTFNFSLVGIDQIINNAAKMRQMSGGQFNIPIVFRGPTGS 121
Query: 595 ASSVAAQHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVMLEDEIMYG 765
A + A HSQ F +W+++ PGLKV++P + DAKGLLK+AIRD DPV+ +E E MYG
Sbjct: 122 AGQLGATHSQAFESWFANTPGLKVVIPSNPYDAKGLLKSAIRDNDPVIFMESEQMYG 178
>UniRef50_Q74AE0 Cluster: Dehydrogenase complex, E1 component, beta
subunit; n=7; Bacteria|Rep: Dehydrogenase complex, E1
component, beta subunit - Geobacter sulfurreducens
Length = 328
Score = 174 bits (423), Expect = 2e-42
Identities = 82/171 (47%), Positives = 111/171 (64%)
Frame = +1
Query: 250 RDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXX 429
RDALN A+ EEM RD V V GE+VA Y+G++KVTRGL ++G++RV DTPI+E
Sbjct: 7 RDALNLALKEEMRRDPSVVVWGEDVALYEGSFKVTRGLLAEFGEERVKDTPISENSIVGV 66
Query: 430 XXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASSVA 609
L+P+ E MT NF++ A+D I+N AK M G +P+V R P G S +
Sbjct: 67 AVGAAMGGLRPVAELMTVNFALLAMDQIVNHMAKIRSMFGGQTYLPMVVRAPGGGGSQLG 126
Query: 610 AQHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVMLEDEIMY 762
AQHSQ ++ HCPG+ V +P + DA+GLLKAAIRD +PV+ LE E++Y
Sbjct: 127 AQHSQSLETYFMHCPGIHVAVPATPADARGLLKAAIRDDNPVMFLEHELLY 177
>UniRef50_A7CXZ3 Cluster: Transketolase central region; n=1;
Opitutaceae bacterium TAV2|Rep: Transketolase central
region - Opitutaceae bacterium TAV2
Length = 327
Score = 167 bits (407), Expect = 2e-40
Identities = 81/175 (46%), Positives = 113/175 (64%)
Frame = +1
Query: 241 VTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXX 420
+T R+A+ A+ EE+ERDE V VLGEEV Q+ GAYKV+ GL +K+G KR++DTPI+E
Sbjct: 4 LTYREAVRAALAEELERDENVVVLGEEVGQFHGAYKVSEGLLEKFGPKRIVDTPISEAGF 63
Query: 421 XXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAAS 600
++P+ E M ++F A D I+N+AA YMS G + PIV RGP +
Sbjct: 64 IGLGVGASMLGIRPVMELMFWSFYSVAFDQILNNAANIRYMSGGQINCPIVIRGPANGGT 123
Query: 601 SVAAQHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVMLEDEIMYG 765
+V A HS ++ PG+KV++P + DAKGLLK+AIRD DPV LE+ ++YG
Sbjct: 124 NVGATHSHTPENVLANHPGVKVVVPATPRDAKGLLKSAIRDNDPVFFLENTLLYG 178
>UniRef50_Q8DMB7 Cluster: Pyruvate dehydrogenase E1 component beta
subunit; n=6; cellular organisms|Rep: Pyruvate
dehydrogenase E1 component beta subunit - Synechococcus
elongatus (Thermosynechococcus elongatus)
Length = 327
Score = 165 bits (400), Expect = 1e-39
Identities = 79/172 (45%), Positives = 106/172 (61%)
Frame = +1
Query: 253 DALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXXX 432
+AL AIDEEMERD VFVLGE+V Y G+YKVT+ L+KKYG+ R++DTPI E
Sbjct: 8 NALRAAIDEEMERDPTVFVLGEDVGHYGGSYKVTKDLYKKYGELRLLDTPIAENSFTGMA 67
Query: 433 XXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASSVAA 612
L+PI E M F + A + I N+A Y S G +PIV RGP G + A
Sbjct: 68 IGAAMTGLRPIVEGMNMGFLLLAFNQIANNAGMLRYTSGGNFKIPIVIRGPGGVGRQLGA 127
Query: 613 QHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVMLEDEIMYGI 768
+HSQ A++ PGLK++ + +AKGLLK+AIRDP+PV+ E ++Y +
Sbjct: 128 EHSQRLEAYFQAVPGLKIVACSTPYNAKGLLKSAIRDPNPVLFFEHVLLYNL 179
>UniRef50_A6Q3I5 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
complex, E1 component, beta subunit; n=1; Nitratiruptor
sp. SB155-2|Rep: Pyruvate/2-oxoglutarate dehydrogenase
complex, E1 component, beta subunit - Nitratiruptor sp.
(strain SB155-2)
Length = 325
Score = 164 bits (398), Expect = 3e-39
Identities = 82/171 (47%), Positives = 108/171 (63%)
Frame = +1
Query: 250 RDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXX 429
R+ALN+AIDE M+ DE V +LGE+V +Y G+Y+V+ GL+ KYG KRVIDTPI E
Sbjct: 4 REALNRAIDESMKADESVVILGEDVGRYGGSYRVSEGLFAKYGPKRVIDTPIAELSIVGN 63
Query: 430 XXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASSVA 609
L+PI E MT NFS+ A+D I+N AAK YMS G + +P+ R P G + +A
Sbjct: 64 AIGMAIGGLRPIAEIMTVNFSLLAMDQIVNHAAKFRYMSGGKMTIPLTIRIPGGVSRQLA 123
Query: 610 AQHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVMLEDEIMY 762
AQHS+ + Y+ PGL VL +A A LK AI DPV+ LE E++Y
Sbjct: 124 AQHSESYETLYASIPGLIVLAASNATYAYHALKHAIFLNDPVIFLEHELLY 174
>UniRef50_Q98FT4 Cluster: Acetoin dehydrogenase (TPP-dependent) beta
chain; n=25; Bacteria|Rep: Acetoin dehydrogenase
(TPP-dependent) beta chain - Rhizobium loti
(Mesorhizobium loti)
Length = 332
Score = 161 bits (392), Expect = 1e-38
Identities = 74/176 (42%), Positives = 112/176 (63%)
Frame = +1
Query: 235 KPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEX 414
+ ++ A+ +A+ M+ DE+VF++GE++ Y GA++VT L ++YG +RVIDTPI+E
Sbjct: 6 RELSYAQAIQEAMAIAMDMDERVFLMGEDIGVYGGAFQVTGDLVERYGTERVIDTPISEL 65
Query: 415 XXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGA 594
++PI EF +F+ A++ I+N AAK +M G V VP+V R P G+
Sbjct: 66 GGAGVAVGAALTGMRPIFEFQFSDFATLAMEQIVNQAAKMRFMLGGEVSVPVVMRFPAGS 125
Query: 595 ASSVAAQHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVMLEDEIMY 762
+ AAQHSQ AW H PGLKV+ P + DAKG+L AA+ DPDPV++ E +++Y
Sbjct: 126 GTGAAAQHSQSLEAWLGHVPGLKVIQPATPYDAKGMLLAAVADPDPVMIFEHKLLY 181
>UniRef50_A3VIE8 Cluster: Acetoin dehydrogenase (TPP-dependent) beta
chain; n=2; Rhodobacterales|Rep: Acetoin dehydrogenase
(TPP-dependent) beta chain - Rhodobacterales bacterium
HTCC2654
Length = 333
Score = 160 bits (389), Expect = 3e-38
Identities = 80/179 (44%), Positives = 111/179 (62%)
Frame = +1
Query: 226 LASKPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPI 405
+ + +T+ A+N+A+ EEM RDE VF+LGE+VA+ +KV GL +++G RVIDTPI
Sbjct: 1 MTMREITLSQAVNEALAEEMRRDETVFILGEDVAEAGTPFKVLSGLVEEFGTDRVIDTPI 60
Query: 406 TEXXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGP 585
+E +P+ + M +F +D + N AAK YMS G + VP+V R
Sbjct: 61 SEPGFVGLAVGAAMTGARPVVDLMFGDFLYLVMDQLCNQAAKQHYMSGGKLSVPMVLRTN 120
Query: 586 NGAASSVAAQHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVMLEDEIMY 762
GA AAQHSQ A +H PGLKV +P SA +AKGL+K AIRD +PVV+ ED++MY
Sbjct: 121 LGATRRSAAQHSQSLQALVAHIPGLKVALPSSAYEAKGLMKTAIRDNNPVVIFEDKLMY 179
>UniRef50_A5UU14 Cluster: Transketolase, central region; n=3;
Chloroflexi (class)|Rep: Transketolase, central region -
Roseiflexus sp. RS-1
Length = 322
Score = 160 bits (388), Expect = 4e-38
Identities = 76/176 (43%), Positives = 110/176 (62%)
Frame = +1
Query: 241 VTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXX 420
+TVR+AL QA+ + M+ DE+VF++GE++ Y Y VT G ++YG +R+ D PI E
Sbjct: 4 ITVREALRQALHDAMQ-DERVFIIGEDIGHYGSTYGVTAGFLEQYGPERIRDAPIAESGI 62
Query: 421 XXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAAS 600
++PI E M+ NFS+ A D + N AAK + M G + VP+V R NG +
Sbjct: 63 VGIAIGAAMVGMRPIAEIMSVNFSLLAFDMLFNHAAKIYSMFGGQMTVPMVLRTTNG-WT 121
Query: 601 SVAAQHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVMLEDEIMYGI 768
++A HSQ F +++H PGLKV+ P + D KG+LKAAI DPDPVV +E +MY +
Sbjct: 122 QLSATHSQSFDVYFAHMPGLKVVAPATPYDMKGMLKAAIEDPDPVVFIEHTLMYTV 177
>UniRef50_Q8IML6 Cluster: CG11876-PB, isoform B; n=2; melanogaster
subgroup|Rep: CG11876-PB, isoform B - Drosophila
melanogaster (Fruit fly)
Length = 273
Score = 158 bits (384), Expect = 1e-37
Identities = 79/127 (62%), Positives = 96/127 (75%), Gaps = 2/127 (1%)
Frame = +1
Query: 196 SRRSFATS-KALASKPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKK 372
++R+F+TS KALA+K +TVRDALN A+D+E+ RD++VF+LGEEVAQYDGAYKV+RGLWKK
Sbjct: 13 AQRAFSTSQKALAAKQMTVRDALNSALDDELARDDRVFILGEEVAQYDGAYKVSRGLWKK 72
Query: 373 YGDKRVIDTPITEXXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHI-INSAAKTFYMSA 549
YGDKRVIDTPITE L+P+CEFMT+NFSMQAIDH I AK
Sbjct: 73 YGDKRVIDTPITEMGFAGIAVGAAMAGLRPVCEFMTWNFSMQAIDHAKILDCAKP---PV 129
Query: 550 GTVPVPI 570
G P+PI
Sbjct: 130 GDRPLPI 136
>UniRef50_A6UDY4 Cluster: Transketolase central region; n=1;
Sinorhizobium medicae WSM419|Rep: Transketolase central
region - Sinorhizobium medicae WSM419
Length = 325
Score = 151 bits (366), Expect = 2e-35
Identities = 73/174 (41%), Positives = 100/174 (57%)
Frame = +1
Query: 241 VTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXX 420
+T RDAL +A+D+ M D + V+GEEV +Y GAY VT+ L K +G R+IDTPI+E
Sbjct: 5 MTYRDALRKALDDAMTDDSSIVVIGEEVGRYGGAYGVTKDLIKIHGADRLIDTPISEPAI 64
Query: 421 XXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAAS 600
L+P+ E M +F +D + N AAK YM G + VP+V R G
Sbjct: 65 VGTAVGAAMTGLRPVAELMYIDFLGMTMDQLANQAAKIRYMFGGQIGVPMVLRTQGGTGR 124
Query: 601 SVAAQHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVMLEDEIMY 762
S AQHSQ AW H PGL++ MP + DA LL+ ++ PDPVV +E + +Y
Sbjct: 125 SAGAQHSQSLEAWVMHTPGLRLAMPATVADAYHLLRQSLTKPDPVVFIEHKALY 178
>UniRef50_P37941 Cluster: 2-oxoisovalerate dehydrogenase subunit
beta; n=39; Bacteria|Rep: 2-oxoisovalerate dehydrogenase
subunit beta - Bacillus subtilis
Length = 327
Score = 151 bits (366), Expect = 2e-35
Identities = 75/170 (44%), Positives = 104/170 (61%)
Frame = +1
Query: 253 DALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXXX 432
DA+N A+ EEMERD +VFVLGE+V + G +K T GL++++G++RV+DTP+ E
Sbjct: 8 DAINLAMKEEMERDSRVFVLGEDVGRKGGVFKATAGLYEQFGEERVMDTPLAESAIAGVG 67
Query: 433 XXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASSVAA 612
++PI E +F M A++ II+ AAK Y S PIV R P G A
Sbjct: 68 IGAAMYGMRPIAEMQFADFIMPAVNQIISEAAKIRYRSNNDWSCPIVVRAPYGGGVHGAL 127
Query: 613 QHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVMLEDEIMY 762
HSQ A +++ PGLK++MP + DAKGLLKAA+RD DPV+ E + Y
Sbjct: 128 YHSQSVEAIFANQPGLKIVMPSTPYDAKGLLKAAVRDEDPVLFFEHKRAY 177
>UniRef50_Q03KN0 Cluster: Pyruvate dehydrogenase (E1) component,
beta subunit; n=24; Streptococcus|Rep: Pyruvate
dehydrogenase (E1) component, beta subunit -
Streptococcus thermophilus (strain ATCC BAA-491 / LMD-9)
Length = 337
Score = 150 bits (363), Expect = 4e-35
Identities = 69/178 (38%), Positives = 110/178 (61%)
Frame = +1
Query: 232 SKPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITE 411
+K + +R+A+N A+ EEM +D +F++GE+V Y G + + G+ ++G+KRV DTPI+E
Sbjct: 9 TKLMALREAVNLAMSEEMRKDPDIFLMGEDVGIYGGDFGTSVGMLAEFGEKRVKDTPISE 68
Query: 412 XXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNG 591
L+PI + +F A+D I+N+ AK YM G + P+ FR +G
Sbjct: 69 AAIAGAAVGAAITGLRPIVDLTFMDFITIALDAIVNNGAKNNYMFGGGLKTPVTFRVASG 128
Query: 592 AASSVAAQHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVMLEDEIMYG 765
+ AAQHSQ +W +H PG+KV+ P +A DAKGLLK++I+D + V+ +E + +YG
Sbjct: 129 SGIGSAAQHSQSLESWLTHIPGIKVVAPGNANDAKGLLKSSIQDNNIVIFMEPKALYG 186
>UniRef50_Q32RM2 Cluster: Pyruvate dehydrogenase E1 component
subunit beta; n=66; cellular organisms|Rep: Pyruvate
dehydrogenase E1 component subunit beta - Zygnema
circumcarinatum (Green alga)
Length = 325
Score = 150 bits (363), Expect = 4e-35
Identities = 67/176 (38%), Positives = 105/176 (59%)
Frame = +1
Query: 241 VTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXX 420
V + +AL Q + EEM+RD +V V+GE+V Y G+YKVT+G ++YGD R++DTPI E
Sbjct: 4 VLLFEALRQGLQEEMDRDPRVMVMGEDVGHYGGSYKVTKGFAERYGDLRLLDTPIAENSF 63
Query: 421 XXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAAS 600
L+P+ E M F + A + I N+A Y S G +PIV RGP G
Sbjct: 64 TGMAIGAAMTGLRPVVEGMNMGFLLLAFNQIANNAGMLHYTSGGNFTIPIVIRGPGGVGR 123
Query: 601 SVAAQHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVMLEDEIMYGI 768
+ A+HSQ +++ PGL+++ + +AKGL+K+AIR +P+++ E ++Y +
Sbjct: 124 QLGAEHSQRLESYFQSVPGLQMVACSTPYNAKGLIKSAIRSDNPIILFEHVLLYNL 179
>UniRef50_A5V539 Cluster: Transketolase, central region; n=4;
Bacteria|Rep: Transketolase, central region -
Sphingomonas wittichii RW1
Length = 324
Score = 147 bits (357), Expect = 2e-34
Identities = 67/169 (39%), Positives = 101/169 (59%)
Frame = +1
Query: 256 ALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXXXX 435
A+N+A+D+ + D V +LGE++A G + VTRGL K+G RVID PI E
Sbjct: 9 AINRALDDALAADPSVLLLGEDIANAGGTFAVTRGLLDKHGPDRVIDMPIAENAIAGMAV 68
Query: 436 XXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASSVAAQ 615
+P+ E M +F +D ++N AAK +M G VP+V R +G + Q
Sbjct: 69 GLALGGFRPVVEIMFMDFMTLTMDALVNQAAKLHFMFGGQSAVPMVVRTQHGGGLNAGPQ 128
Query: 616 HSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVMLEDEIMY 762
HSQC AW++H PGLKV++P + +DA LL++AI DP+PV+ +E++ +Y
Sbjct: 129 HSQCLEAWFAHIPGLKVVVPATLDDAYALLRSAIDDPNPVLFVENKALY 177
>UniRef50_P96103 Cluster: Pyruvate dehydrogenase complex E1 beta
subunit; n=3; Proteobacteria|Rep: Pyruvate dehydrogenase
complex E1 beta subunit - Thiobacillus ferrooxidans
(Acidithiobacillus ferrooxidans)
Length = 343
Score = 146 bits (354), Expect = 5e-34
Identities = 73/168 (43%), Positives = 99/168 (58%)
Frame = +1
Query: 265 QAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXXXXXXX 444
+A DEEM RD VF +GE++ G YK T GL+ KYG++RVIDTPI+E
Sbjct: 12 RAHDEEMARDPLVFAMGEDIGVAGGTYKATSGLFAKYGEQRVIDTPISENSYTGIGVGAA 71
Query: 445 XXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASSVAAQHSQ 624
+PI E M+ NF+ A+D ++N+AAK YMS G + P V R P G A + AQHS
Sbjct: 72 MIGARPIVEIMSVNFAWLAMDQLMNNAAKIHYMSGGRIRCPFVMRVPGGTAHQLGAQHSA 131
Query: 625 CFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVMLEDEIMYGI 768
+ GL+V+ P + DA GLLK+A+ DPVV++E E MY +
Sbjct: 132 RMEKVFMGISGLRVVTPATPRDAYGLLKSAVXLNDPVVIIEHESMYNL 179
>UniRef50_A1SN85 Cluster: Transketolase, central region; n=4;
cellular organisms|Rep: Transketolase, central region -
Nocardioides sp. (strain BAA-499 / JS614)
Length = 347
Score = 145 bits (352), Expect = 9e-34
Identities = 77/180 (42%), Positives = 102/180 (56%)
Frame = +1
Query: 232 SKPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITE 411
S+ +T A+ +AI EMERD VF LGE+V Y G + T GL ++G RVIDTPI+E
Sbjct: 14 SRRLTTSKAIVEAIAFEMERDPSVFYLGEDVGSYGGIFGSTGGLLDRFGKDRVIDTPISE 73
Query: 412 XXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNG 591
++PI E M +F +D I N AK + S G V VP+V G
Sbjct: 74 TAFIGLGIGAAVEGMRPIVELMFADFMGVCLDQIYNHMAKIHFESGGNVKVPMVLTMAAG 133
Query: 592 AASSVAAQHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVMLEDEIMYGIP 771
S AQHSQC ++H PG+KV++P S DAKGL+ AAIRD +PVV L + + G+P
Sbjct: 134 GGYSDGAQHSQCLWGTFAHLPGMKVVVPSSPADAKGLMTAAIRDDNPVVYLFHKGVMGLP 193
>UniRef50_A0LFE7 Cluster: Transketolase domain protein; n=1;
Syntrophobacter fumaroxidans MPOB|Rep: Transketolase
domain protein - Syntrophobacter fumaroxidans (strain
DSM 10017 / MPOB)
Length = 325
Score = 145 bits (352), Expect = 9e-34
Identities = 77/179 (43%), Positives = 104/179 (58%), Gaps = 2/179 (1%)
Frame = +1
Query: 241 VTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKV--TRGLWKKYGDKRVIDTPITEX 414
+T+ A+NQA+ EEM RD VF+ GE V A V T GL +++G RV DTP++E
Sbjct: 4 LTMGQAVNQALREEMLRDPNVFIAGEGVGVSIHAAPVLPTFGLLEEFGPDRVKDTPVSEA 63
Query: 415 XXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGA 594
L+P+ E M F A D I+N AAK Y+S G P+V R +GA
Sbjct: 64 AIAGLAVGASVMGLRPVVEIMFNPFVTLASDMIVNHAAKLRYLSGGKSTFPMVVRIKSGA 123
Query: 595 ASSVAAQHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVMLEDEIMYGIP 771
QHS AW +HCPG++V+MP + DAKGLLK+AIRD +PVV +ED ++Y +P
Sbjct: 124 GFKAGCQHSHNLEAWLAHCPGIRVVMPSTPADAKGLLKSAIRDDNPVVFIEDMLLYFVP 182
>UniRef50_A5V352 Cluster: Transketolase, central region; n=1;
Sphingomonas wittichii RW1|Rep: Transketolase, central
region - Sphingomonas wittichii RW1
Length = 334
Score = 144 bits (348), Expect = 3e-33
Identities = 76/189 (40%), Positives = 102/189 (53%), Gaps = 2/189 (1%)
Frame = +1
Query: 211 ATSKALASKPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYD--GAYKVTRGLWKKYGDK 384
AT A + A+N AI + ME D+ V VLGE+VA + G VT+GL ++GD
Sbjct: 2 ATQTAAKPAKANILQAINAAIADAMEADDNVVVLGEDVADPEEGGVCGVTKGLSSRFGDA 61
Query: 385 RVIDTPITEXXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPV 564
RV TPI+E KP+ E M NF+ A+D I+N AAK +MS G V
Sbjct: 62 RVRSTPISEQAIVGAAIGASLVGFKPVAEIMLMNFTTVAMDMIVNHAAKLRFMSGGQTHV 121
Query: 565 PIVFRGPNGAASSVAAQHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVML 744
PIV R G + QH AW++H G+KV+ P S DA GL+++AI DPDPV+ +
Sbjct: 122 PIVIRTMTGTGFASGGQHCDYLEAWFAHTAGIKVVAPSSPRDAYGLMRSAIDDPDPVLFI 181
Query: 745 EDEIMYGIP 771
E+ Y P
Sbjct: 182 ENLPTYWTP 190
>UniRef50_Q3WCG4 Cluster: Transketolase, central
region:Transketolase, C terminal; n=7; Bacteria|Rep:
Transketolase, central region:Transketolase, C terminal
- Frankia sp. EAN1pec
Length = 351
Score = 143 bits (347), Expect = 4e-33
Identities = 73/169 (43%), Positives = 98/169 (57%)
Frame = +1
Query: 241 VTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXX 420
+T+R+ALN A+D+ + RDE+VF+LGE++A G+ T+GL KYG RV+DTPI+E
Sbjct: 21 MTMREALNLALDQALARDERVFLLGEDIAD-PGSSGPTKGLSTKYGADRVLDTPISEAAI 79
Query: 421 XXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAAS 600
+P+ E M +F A D I+N AAK +M+ G PI R
Sbjct: 80 VGAAIGAAMEGFRPVAEIMIMDFIGIAADQIVNHAAKLRFMTGGRTTAPITVRTQVYGGL 139
Query: 601 SVAAQHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVMLE 747
A HSQ AW+ H PGLKV++P + DAKGLL +AI D DP V LE
Sbjct: 140 GTGATHSQSLEAWFMHVPGLKVIVPSTPRDAKGLLASAIFDDDPCVFLE 188
>UniRef50_Q5L234 Cluster: Thiamine pyrophosphate-dependent
dehydrogenases, E1 component beta subunit; n=13;
cellular organisms|Rep: Thiamine pyrophosphate-dependent
dehydrogenases, E1 component beta subunit - Geobacillus
kaustophilus
Length = 339
Score = 142 bits (345), Expect = 7e-33
Identities = 74/176 (42%), Positives = 103/176 (58%)
Frame = +1
Query: 241 VTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXX 420
+T AL +AI EMERD VFV+GE+V Y G + T GL++K+G +RVIDTPI+E
Sbjct: 9 LTGNKALAEAIRLEMERDPNVFVMGEDVGVYGGIFGATEGLFQKFGPERVIDTPISETAF 68
Query: 421 XXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAAS 600
++PI E M +F +D I N AK YMS G V +P+V G
Sbjct: 69 IGAAIGAAAEGMRPIVELMFVDFFGVCMDQIYNHMAKIPYMSGGRVKLPMVLMTAVGGGY 128
Query: 601 SVAAQHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVMLEDEIMYGI 768
S AAQHSQ A ++H PG+KV+ P + D KG++ +AIRD +PVV + + + G+
Sbjct: 129 SDAAQHSQTLYATFAHLPGMKVVAPSTPYDLKGMMISAIRDDNPVVFMFHKTLQGL 184
>UniRef50_A0LTR0 Cluster: Transketolase, central region; n=2;
Actinobacteria (class)|Rep: Transketolase, central
region - Acidothermus cellulolyticus (strain ATCC 43068
/ 11B)
Length = 327
Score = 141 bits (342), Expect = 2e-32
Identities = 69/176 (39%), Positives = 97/176 (55%)
Frame = +1
Query: 241 VTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXX 420
++ R+A+ + + +EM RD +V ++GE+V G +K T GL ++G RVIDTPI E
Sbjct: 4 LSYREAVARGLAQEMARDSRVVLIGEDVGAAGGVFKATVGLLDQFGPSRVIDTPIAEQAI 63
Query: 421 XXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAAS 600
++P+ E M +F D I N AKT YM+ G + +P+V R NG
Sbjct: 64 IGAAMGAAMNGMRPVAEIMFSDFFAVCWDQIANQIAKTRYMTHGQISLPLVIRTANGGGV 123
Query: 601 SVAAQHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVMLEDEIMYGI 768
AQHSQ W PGLKV+ P + D GLL AAIRDPDPV+ E + +Y +
Sbjct: 124 RFGAQHSQSVENWAMMVPGLKVVAPSTPRDVVGLLAAAIRDPDPVIFFEHKSLYAV 179
>UniRef50_P35488 Cluster: Pyruvate dehydrogenase E1 component
subunit beta; n=4; Bacteria|Rep: Pyruvate dehydrogenase
E1 component subunit beta - Acholeplasma laidlawii
Length = 327
Score = 141 bits (341), Expect = 2e-32
Identities = 72/174 (41%), Positives = 94/174 (54%)
Frame = +1
Query: 241 VTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXX 420
+T+ +A+NQAID+ ME+DE + V GE+ G ++VT GL KKYG+ RV DTPI E
Sbjct: 4 ITLLEAINQAIDQAMEKDESIVVFGEDAGFEGGVFRVTAGLQKKYGETRVFDTPIAESAI 63
Query: 421 XXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAAS 600
LKPI E F ++ AA+ S G VP+V R P+G
Sbjct: 64 VGSAVGMAINGLKPIAEIQFDGFIFPGYTDLVTHAARMRNRSRGQFTVPMVLRLPHGGGI 123
Query: 601 SVAAQHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVMLEDEIMY 762
HS+ + PGLKV+ P + DAKGLL AAI DPDPVV LE + +Y
Sbjct: 124 RALEHHSEALEVLFGSIPGLKVVTPSTPYDAKGLLLAAINDPDPVVFLEPKRIY 177
>UniRef50_Q72GU2 Cluster: 2-oxoisovalerate dehydrogenase subunit
beta; n=12; cellular organisms|Rep: 2-oxoisovalerate
dehydrogenase subunit beta - Thermus thermophilus
(strain HB27 / ATCC BAA-163 / DSM 7039)
Length = 324
Score = 141 bits (341), Expect = 2e-32
Identities = 72/174 (41%), Positives = 99/174 (56%)
Frame = +1
Query: 241 VTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXX 420
+T+ ALN+A+DEEM +D +V VLGE+V + G + VT GL +KYG RV+DTP++E
Sbjct: 4 MTMVQALNRALDEEMAKDPRVVVLGEDVGKRGGVFLVTEGLLQKYGPDRVMDTPLSEAAI 63
Query: 421 XXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAAS 600
L+P+ E ++ D +++ AK Y S G P+V R P+G
Sbjct: 64 VGAALGMAAHGLRPVAEIQFADYIFPGFDQLVSQVAKLRYRSGGQFTAPLVVRMPSGGGV 123
Query: 601 SVAAQHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVMLEDEIMY 762
HSQ A + H GLKV+ + DAKGLLKAAIRD DPVV LE + +Y
Sbjct: 124 RGGHHHSQSPEAHFVHTAGLKVVAVSTPYDAKGLLKAAIRDEDPVVFLEPKRLY 177
>UniRef50_Q9Z9E8 Cluster: (Pyruvate) Oxoisovalerate Dehydrogenase
Alpha/Beta Fusion ((Pyruvate) oxoisovalerate
dehydrogenase alpha and beta fusion); n=7;
Chlamydiaceae|Rep: (Pyruvate) Oxoisovalerate
Dehydrogenase Alpha/Beta Fusion ((Pyruvate)
oxoisovalerate dehydrogenase alpha and beta fusion) -
Chlamydia pneumoniae (Chlamydophila pneumoniae)
Length = 678
Score = 140 bits (338), Expect = 5e-32
Identities = 71/179 (39%), Positives = 103/179 (57%), Gaps = 2/179 (1%)
Frame = +1
Query: 232 SKPVTVRDALNQAIDEEMERDEKVFVLGEEVA-QYDGAYKVTRGLWKKYGDKRVIDTPIT 408
S+P +RDA+++A+ EEM RD V V GE+VA G + VTR L +K+G +R ++P+
Sbjct: 348 SEPKVMRDAISEALVEEMTRDSGVIVFGEDVAGDKGGVFGVTRNLTEKFGPQRCFNSPLA 407
Query: 409 EXXXXXXXXXXXXXXL-KPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGP 585
E + KP+ E ++ I+ + + A+ +Y SAG VP+V R P
Sbjct: 408 EATIIGTAIGMALDGIHKPVVEIQFADYIWPGINQLFSEASSIYYRSAGEWEVPLVIRAP 467
Query: 586 NGAASSVAAQHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVMLEDEIMY 762
+G HSQ + +HCPG+KV P +A DAK LLKAAIRDP+PVV LE + +Y
Sbjct: 468 SGGYIQGGPYHSQSIEGFLAHCPGIKVAYPSNAADAKALLKAAIRDPNPVVFLEHKALY 526
>UniRef50_A0Z5N8 Cluster: Acetoin dehydrogenase E1 component, beta
subunit; n=1; marine gamma proteobacterium HTCC2080|Rep:
Acetoin dehydrogenase E1 component, beta subunit -
marine gamma proteobacterium HTCC2080
Length = 325
Score = 140 bits (338), Expect = 5e-32
Identities = 73/175 (41%), Positives = 97/175 (55%), Gaps = 1/175 (0%)
Frame = +1
Query: 241 VTVRDALNQAIDEEMERDEKVFVLGEEVAQ-YDGAYKVTRGLWKKYGDKRVIDTPITEXX 417
++VR+A+N + EEM RD +V ++GE+VA G Y VT GL +K+G RVIDTPITE
Sbjct: 3 MSVREAINLTLHEEMARDPRVVIMGEDVASGQGGVYGVTAGLTEKFGVARVIDTPITESA 62
Query: 418 XXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAA 597
L+P+ E M +F +D ++N AK YM G P+V R GA
Sbjct: 63 IVGAAGGAALTGLRPVAELMFIDFLGVCLDQLLNQIAKFRYMFGGQARTPLVIRTMIGAG 122
Query: 598 SSVAAQHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVMLEDEIMY 762
QHSQ + PG+KV+ P +A DAKGLL AIR DPVV E + +Y
Sbjct: 123 EGTGPQHSQILYPMLAAIPGIKVVAPSNAADAKGLLAEAIRQDDPVVFCEHKALY 177
>UniRef50_Q1AZ53 Cluster: Transketolase, central region; n=1;
Rubrobacter xylanophilus DSM 9941|Rep: Transketolase,
central region - Rubrobacter xylanophilus (strain DSM
9941 / NBRC 16129)
Length = 330
Score = 139 bits (337), Expect = 6e-32
Identities = 71/168 (42%), Positives = 95/168 (56%)
Frame = +1
Query: 241 VTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXX 420
++ +AL +A+DEE+ RDE+ F +GE+V + G + GL +KYG +RV DTPI+E
Sbjct: 5 ISYTEALREALDEELGRDERTFFMGEDVGAFGGIFGEAAGLQQKYGKERVFDTPISETFI 64
Query: 421 XXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAAS 600
L+PI E +F A+D I N AAK YM G VP+V P GA
Sbjct: 65 VGGGVGAAITGLRPIVELQFADFVSVAMDEIYNKAAKWRYMHGGLFKVPLVIIAPEGAMG 124
Query: 601 SVAAQHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVML 744
+HSQC A + GL VL P + DAKGLLK+AIRD +PV+ L
Sbjct: 125 GAGPEHSQCPEALFWSAAGLYVLTPATPADAKGLLKSAIRDDNPVLFL 172
>UniRef50_Q28MR4 Cluster: Dehydrogenase E1 component; n=8;
Bacteria|Rep: Dehydrogenase E1 component - Jannaschia
sp. (strain CCS1)
Length = 675
Score = 138 bits (335), Expect = 1e-31
Identities = 68/186 (36%), Positives = 105/186 (56%)
Frame = +1
Query: 205 SFATSKALASKPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDK 384
++ A S+ +T A+ +A ++M RD + +LGE+V + G + +T+GL+ +G
Sbjct: 340 AYPAPPAAGSRKITYAQAITEAFAQQMARDPDLLILGEDVGRTGGIFGLTKGLFDTFGPD 399
Query: 385 RVIDTPITEXXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPV 564
RV DTPI+E + + E ++F +D I+N AAK +M G V
Sbjct: 400 RVRDTPISEGAIATCGVGAAMRGKRVVVEAQLWDFVTLMMDAIVNQAAKARFMLGGKAKV 459
Query: 565 PIVFRGPNGAASSVAAQHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVML 744
PIVFRGP GA +AAQH Q +++ PGL++ P +A DAKGL+ AA+R PVV L
Sbjct: 460 PIVFRGPQGAGIRLAAQHCQSLEMLFANVPGLEIYAPSTAYDAKGLMAAALRHDGPVVFL 519
Query: 745 EDEIMY 762
E +++Y
Sbjct: 520 EHKLLY 525
>UniRef50_A0UXT4 Cluster: Transketolase-like; n=1; Clostridium
cellulolyticum H10|Rep: Transketolase-like - Clostridium
cellulolyticum H10
Length = 346
Score = 136 bits (329), Expect = 6e-31
Identities = 67/183 (36%), Positives = 102/183 (55%)
Frame = +1
Query: 214 TSKALASKPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVI 393
T + + ++ +DAL +A+D+ + RD +VF++GE V G + T+GL +KYG RV
Sbjct: 17 TDDSEIGRMISYKDALYEALDQSLARDPRVFIMGEGVDDPGGVFGTTKGLHEKYGRNRVF 76
Query: 394 DTPITEXXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIV 573
DTPI E L+PI +F + ++D ++N AAK YM+ G V VP+V
Sbjct: 77 DTPIAENSLTGIAAGAAMAGLRPIFVHSRMDFLLLSLDQLVNHAAKWSYMTGGKVKVPLV 136
Query: 574 FRGPNGAASSVAAQHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVMLEDE 753
R + AQHSQC + PGLK+ +P + DAKGLL ++I D +PV+ +E
Sbjct: 137 VRTVSARGWGSGAQHSQCLHGMLMNAPGLKIAVPATPYDAKGLLISSIIDNNPVLFVEHR 196
Query: 754 IMY 762
+Y
Sbjct: 197 WLY 199
>UniRef50_Q5UWH0 Cluster: Pyruvate dehydrogenase; n=55; cellular
organisms|Rep: Pyruvate dehydrogenase - Haloarcula
marismortui (Halobacterium marismortui)
Length = 338
Score = 136 bits (328), Expect = 8e-31
Identities = 66/177 (37%), Positives = 101/177 (57%)
Frame = +1
Query: 232 SKPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITE 411
++ +T+ +A+ + EM +D+ V VLGE+V + G ++ T L++++G+ RVIDTP+ E
Sbjct: 13 AQSLTLVEAIQDGLYTEMSQDDTVVVLGEDVGKNGGVFRATDQLYEEFGEDRVIDTPLAE 72
Query: 412 XXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNG 591
+KP+ E F A D I++ AA+ S G VP+V R P G
Sbjct: 73 AGIIGASIGLAQTGMKPVPEMQFMGFMYPAFDQIVSHAARLRSRSQGQYSVPMVIRAPYG 132
Query: 592 AASSVAAQHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVMLEDEIMY 762
HS+ A++ H PGLKV+ P + DAKGLL A+IRDPDPV+ LE +++Y
Sbjct: 133 GGIRAPEHHSESKEAFFVHEPGLKVVSPSTPYDAKGLLAASIRDPDPVIFLEPKLIY 189
>UniRef50_Q5VGY3 Cluster: Pyruvate dehydrogenase beta subunit; n=2;
Plasmodium falciparum|Rep: Pyruvate dehydrogenase beta
subunit - Plasmodium falciparum
Length = 415
Score = 135 bits (327), Expect = 1e-30
Identities = 67/172 (38%), Positives = 102/172 (59%)
Frame = +1
Query: 247 VRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXXX 426
+ +AL+ AI EEM++D+ V+VLGE+V Y G+YKVT+ L +G RV+DTPI E
Sbjct: 94 ISEALHMAIYEEMKKDKGVYVLGEDVGLYGGSYKVTKNLAHFFGFSRVLDTPICENAFMG 153
Query: 427 XXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASSV 606
L+PI E M +F + A + I N+A YM G +PIV RGP G +
Sbjct: 154 LGIGSAINDLRPIIEGMNLSFLILAFNQISNNACMMRYMCDGQFNIPIVIRGPGGIGKQL 213
Query: 607 AAQHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVMLEDEIMY 762
+HSQ ++ PG+K++ + +A+GLLK+AIRD +P++ +E ++Y
Sbjct: 214 GPEHSQRIESYLMSIPGIKIVSCSTPFNARGLLKSAIRDNNPILFIEHVLLY 265
>UniRef50_Q5HKL9 Cluster: Acetoin dehydrogenase, E1 component, beta
subunit; n=4; Bacilli|Rep: Acetoin dehydrogenase, E1
component, beta subunit - Staphylococcus epidermidis
(strain ATCC 35984 / RP62A)
Length = 346
Score = 134 bits (325), Expect = 2e-30
Identities = 74/189 (39%), Positives = 107/189 (56%), Gaps = 12/189 (6%)
Frame = +1
Query: 235 KPVTVRDALNQAIDEEMERDEKVFVLGEEVA------------QYDGAYKVTRGLWKKYG 378
+ +T A+N+AID+ ME+DE V ++G +V+ + G + VT+GL KKY
Sbjct: 5 RKLTFMGAINEAIDQSMEKDEDVILIGTDVSGGAKVDHIKDDDTFGGVFGVTKGLAKKYS 64
Query: 379 DKRVIDTPITEXXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTV 558
KRVIDTPI E L+PI E M +F +D I+N AK YM G
Sbjct: 65 RKRVIDTPIAEHITLSTAVGAAATGLRPIAELMFNDFIGFGLDPILNQGAKMRYMFGGKA 124
Query: 559 PVPIVFRGPNGAASSVAAQHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVV 738
+P+V R +GA +S AAQHSQ ++ PG+KV++P + DAKGLL +AI++ + VV
Sbjct: 125 KIPLVVRTVHGAGASAAAQHSQSLYNMFAAIPGVKVVVPSNPYDAKGLLMSAIQEDNLVV 184
Query: 739 MLEDEIMYG 765
ED+ + G
Sbjct: 185 FSEDKTLLG 193
>UniRef50_Q9KG98 Cluster: Pyruvate dehydrogenase E1 (Lipoamide) beta
subunit; n=24; Bacteria|Rep: Pyruvate dehydrogenase E1
(Lipoamide) beta subunit - Bacillus halodurans
Length = 328
Score = 134 bits (324), Expect = 2e-30
Identities = 66/179 (36%), Positives = 99/179 (55%)
Frame = +1
Query: 226 LASKPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPI 405
+ S+ T+ A+NQ +D+ + ++ V +LGE++ G ++ T GL++KYG RV+DTP+
Sbjct: 1 MGSQQQTMLQAINQTLDDLLATNDDVMLLGEDIGINGGVFRATDGLYEKYGKDRVVDTPL 60
Query: 406 TEXXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGP 585
E +PI E F + +I+ AA+ Y + G VP+V R P
Sbjct: 61 AESGIIGSAIGLAMNGKRPIVEIQFLAFIYPGFEQLISHAARMRYRTRGQYNVPMVIRTP 120
Query: 586 NGAASSVAAQHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVMLEDEIMY 762
GA HS+ A+++H PGLKV+ P + DAKGLL AA DPDPV+ LED +Y
Sbjct: 121 YGAGIRGPELHSESVEAFFAHTPGLKVVAPSNPYDAKGLLTAATSDPDPVIFLEDTKLY 179
>UniRef50_Q97YF5 Cluster: Pyruvate dehydrogenase, beta subunit
(Lipoamide); n=1; Sulfolobus solfataricus|Rep: Pyruvate
dehydrogenase, beta subunit (Lipoamide) - Sulfolobus
solfataricus
Length = 332
Score = 134 bits (324), Expect = 2e-30
Identities = 64/175 (36%), Positives = 98/175 (56%)
Frame = +1
Query: 247 VRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXXX 426
+ A+ + I +EMER++++ VLGE+V + + T GL+ K+G KRVIDTPITE
Sbjct: 6 IAQAIAEGIRQEMERNDRIVVLGEDVTYWGAVFGFTMGLFDKFGRKRVIDTPITEQTFMG 65
Query: 427 XXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASSV 606
L P+ M +F D + N AK +YMS G P+PI G
Sbjct: 66 ISVGAASSGLHPVVSLMFVDFLGAGFDQMFNHMAKNYYMSGGQYPMPITVITAIGGGYGD 125
Query: 607 AAQHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVMLEDEIMYGIP 771
++QHSQ + ++H PG KV++P + DAKGL A+RD +PV++ +++ G+P
Sbjct: 126 SSQHSQVLYSLFAHLPGFKVIVPSTPYDAKGLTIKALRDNNPVIIFGHKLLTGLP 180
>UniRef50_Q0LRY7 Cluster: Dehydrogenase, E1 component:Transketolase,
central region:Transketolase-like; n=3; cellular
organisms|Rep: Dehydrogenase, E1
component:Transketolase, central
region:Transketolase-like - Caulobacter sp. K31
Length = 680
Score = 134 bits (323), Expect = 3e-30
Identities = 73/211 (34%), Positives = 111/211 (52%), Gaps = 2/211 (0%)
Frame = +1
Query: 136 IIFKMALKSSPAVLGMLTRLSRRSFATSKALA--SKPVTVRDALNQAIDEEMERDEKVFV 309
++ ++ +P+ L + ++ KA A S+ ++ +A+N A+ E+E DE+ +
Sbjct: 311 LVLRVMASPAPSPADALQPIHGQTTEDRKARAPESRSMSYVEAVNAALRAELEEDERTVL 370
Query: 310 LGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXXXXXXXXXXLKPICEFMTFNF 489
GE+V + G + +R L + +G RV DTPI E LKPI E M +F
Sbjct: 371 YGEDVGKSGGIFAASRYLQRDFGADRVFDTPIAENAILGSAVGAALGGLKPIVEIMWADF 430
Query: 490 SMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASSVAAQHSQCFGAWYSHCPGLKVL 669
A+D ++N AA Y++AG VP+V R GA AQHSQ A +H PGLKV
Sbjct: 431 IFVALDQLVNQAANVRYITAGKSSVPLVVRTQQGATPGSCAQHSQSIEAILAHVPGLKVA 490
Query: 670 MPYSAEDAKGLLKAAIRDPDPVVMLEDEIMY 762
+ + DA LL+AA DPDP V++E +Y
Sbjct: 491 LAATPHDAYTLLRAAAADPDPCVVIEARALY 521
>UniRef50_A0H598 Cluster: Transketolase, central region; n=2;
Chloroflexus|Rep: Transketolase, central region -
Chloroflexus aggregans DSM 9485
Length = 343
Score = 132 bits (320), Expect = 7e-30
Identities = 66/177 (37%), Positives = 98/177 (55%)
Frame = +1
Query: 232 SKPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITE 411
++ +T +A+ A+ EM+RD +V ++GE++ Y GA+KVT+GL +++G+ +VIDTP+TE
Sbjct: 20 TRELTYLEAIRAALRYEMQRDLRVLIMGEDIGVYGGAFKVTQGLIEEFGEDQVIDTPMTE 79
Query: 412 XXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNG 591
P+ E +F D I+ AA + PVPI R P G
Sbjct: 80 LAMIYAAIGMSFEGFLPVVEMQFADFISTGFDAIVQFAATNHF--RWRQPVPITIRAPGG 137
Query: 592 AASSVAAQHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVMLEDEIMY 762
HSQ AW+ H PGLKV+ P + DA GLL +AIRDP+PV+ E + +Y
Sbjct: 138 GGLRAGPFHSQSNEAWFVHTPGLKVVAPATPADAYGLLLSAIRDPNPVIYYETKYLY 194
>UniRef50_Q0MX86 Cluster: Pyruvate dehydrogenase beta-subunit; n=3;
Bacteria|Rep: Pyruvate dehydrogenase beta-subunit -
consortium cosmid clone pGZ1
Length = 333
Score = 132 bits (319), Expect = 9e-30
Identities = 70/174 (40%), Positives = 99/174 (56%)
Frame = +1
Query: 241 VTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXX 420
+T A ++ M D V LGE++ + G + RGL + +G +RVIDTPI+E
Sbjct: 9 MTYSAAAAASLAAAMHADSSVVALGEDLGR-GGIFGQYRGLLEAFGPERVIDTPISEATI 67
Query: 421 XXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAAS 600
L+P+ E +F++ A+D I+N AAK YM G VP+V R P G S
Sbjct: 68 AGSAVGMALTGLRPVVEMRVVDFALCAMDEIVNQAAKNRYMFGGQGRVPMVIRMPIGIWS 127
Query: 601 SVAAQHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVMLEDEIMY 762
S AAQHSQ AW++H PGL VL P + +D LL+AA+R+ DPVV LE + ++
Sbjct: 128 SSAAQHSQSLEAWFAHVPGLVVLCPATPQDNHSLLRAAVRNADPVVYLEHKELW 181
>UniRef50_A5UVZ0 Cluster: Transketolase, central region; n=5;
Bacteria|Rep: Transketolase, central region -
Roseiflexus sp. RS-1
Length = 327
Score = 132 bits (319), Expect = 9e-30
Identities = 69/174 (39%), Positives = 96/174 (55%)
Frame = +1
Query: 241 VTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXX 420
+T +A+ A+ + M D+++ VLGE+VA G + T GL ++G++RVID PI E
Sbjct: 4 MTFIEAIRSAMHDAMAADDRIIVLGEDVAVRGGVFLATEGLLARFGERRVIDMPIAECAI 63
Query: 421 XXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAAS 600
L PI E ++ AID I+N AA+ Y S G PIV R P GA
Sbjct: 64 VGVAIGAALHGLLPIAEIQFADYIYPAIDQILNEAARLRYRSNGDWSCPIVVRAPFGAGI 123
Query: 601 SVAAQHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVMLEDEIMY 762
A HSQ ++ PG+KV++P + DAKGLL AAI DPDPV+ E + +Y
Sbjct: 124 HGALYHSQSVERLFTSTPGIKVVIPSTPADAKGLLIAAIHDPDPVIFFEHKQLY 177
>UniRef50_A7BPK5 Cluster: Pyruvate dehydrogenase, E1 component, beta
subunit; n=1; Beggiatoa sp. PS|Rep: Pyruvate
dehydrogenase, E1 component, beta subunit - Beggiatoa
sp. PS
Length = 362
Score = 132 bits (318), Expect = 1e-29
Identities = 69/180 (38%), Positives = 100/180 (55%)
Frame = +1
Query: 229 ASKPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPIT 408
+ + +T A+ + + + ME+D V V+GE V + T GL +++G KRV D P+
Sbjct: 7 SQRELTYSQAILEGLRQCMEQDSSVIVIGEGVPDPKAIFGTTEGLLEQFGPKRVFDMPLA 66
Query: 409 EXXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPN 588
E L+P+ +FS+ A+D IIN+AAK YM G V VP+V R
Sbjct: 67 ENGMTGICIGAALDGLRPVMVHQRIDFSLLALDQIINNAAKWHYMFDGAVSVPLVIRVLI 126
Query: 589 GAASSVAAQHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVMLEDEIMYGI 768
G QHSQ A ++H PGLKV+MP +A DAKGLL AAI+D +PV+ +E ++ I
Sbjct: 127 GRGWGQGPQHSQSLQALFAHIPGLKVVMPTTARDAKGLLIAAIKDNNPVIFIEHRWLHHI 186
>UniRef50_O34591 Cluster: Acetoin:2,6-dichlorophenolindophenol
oxidoreductase subunit beta; n=65; Bacteria|Rep:
Acetoin:2,6-dichlorophenolindophenol oxidoreductase
subunit beta - Bacillus subtilis
Length = 342
Score = 129 bits (311), Expect = 9e-29
Identities = 72/191 (37%), Positives = 101/191 (52%), Gaps = 12/191 (6%)
Frame = +1
Query: 232 SKPVTVRDALNQAIDEEMERDEKVFVLGEEVA------------QYDGAYKVTRGLWKKY 375
++ +++ DA+N+A+ M +DE V ++GE+VA + G VT+GL +++
Sbjct: 2 ARVISMSDAINEAMKLAMRKDENVLLIGEDVAGGAAVDHLQDDEAWGGVLGVTKGLVQEF 61
Query: 376 GDKRVIDTPITEXXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGT 555
G RV+DTPI+E L+PI E M +F D +IN AK YM G
Sbjct: 62 GRTRVLDTPISEAGYMGAAMAAASTGLRPIAELMFNDFIGTCFDQVINQGAKFRYMFGGK 121
Query: 556 VPVPIVFRGPNGAASSVAAQHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPV 735
VPI R GA AAQHSQ ++ PGLK ++P + DAKGLL AAI D DPV
Sbjct: 122 AQVPITVRTTYGAGFRAAAQHSQSLYGLFTSIPGLKTVVPSNPYDAKGLLLAAIEDNDPV 181
Query: 736 VMLEDEIMYGI 768
ED+ Y +
Sbjct: 182 FFFEDKTSYNM 192
>UniRef50_Q0W152 Cluster: Pyruvate dehydrogenase complex E1,
transketolase beta subunit; n=8; cellular organisms|Rep:
Pyruvate dehydrogenase complex E1, transketolase beta
subunit - Uncultured methanogenic archaeon RC-I
Length = 325
Score = 127 bits (306), Expect = 4e-28
Identities = 63/169 (37%), Positives = 92/169 (54%)
Frame = +1
Query: 256 ALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXXXX 435
A+N A+ EM RD V V+GE+V + G ++ T GL +K+G +RV+DTP++E
Sbjct: 9 AVNDALMVEMGRDPSVIVMGEDVGKEGGVFRATTGLQEKFGRERVVDTPLSENGIIGTAI 68
Query: 436 XXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASSVAAQ 615
+KP+CE F + +I A++ + G VP+V R P G
Sbjct: 69 GLALNGIKPVCEIQFSGFVYAGYEELIAHASRIRQRTMGRFSVPMVVRMPYGGGVKALEH 128
Query: 616 HSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVMLEDEIMY 762
HS+ + + H PGLKV+ P + D KGLL A+IRDPDPV+ LE +Y
Sbjct: 129 HSESYETIFLHDPGLKVVAPSTPADLKGLLIASIRDPDPVIFLEHIRLY 177
>UniRef50_Q9I1M1 Cluster: 2-oxoisovalerate dehydrogenase subunit
beta; n=67; cellular organisms|Rep: 2-oxoisovalerate
dehydrogenase subunit beta - Pseudomonas aeruginosa
Length = 350
Score = 124 bits (298), Expect = 3e-27
Identities = 66/177 (37%), Positives = 94/177 (53%)
Frame = +1
Query: 241 VTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXX 420
+T+ AL A+D +ERD+ V V G++V + G ++ T GL KKYG RV D PI+E
Sbjct: 17 MTMIQALRSAMDIMLERDDDVVVFGQDVGYFGGVFRCTEGLQKKYGTSRVFDAPISESGI 76
Query: 421 XXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAAS 600
L+P+ E ++ A D +I+ AA+ Y SAG VP+ R P G
Sbjct: 77 IGAAVGMGAYGLRPVVEIQFADYVYPASDQLISEAARLRYRSAGDFIVPMTVRMPCGGGI 136
Query: 601 SVAAQHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVMLEDEIMYGIP 771
HSQ A ++ GL+ +MP + DAKGLL A I + DPV+ LE + +Y P
Sbjct: 137 YGGQTHSQSPEAMFTQVCGLRTVMPSNPYDAKGLLIACIENDDPVIFLEPKRLYNGP 193
>UniRef50_Q1ARM1 Cluster: Transketolase-like protein; n=2;
Bacteria|Rep: Transketolase-like protein - Rubrobacter
xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 330
Score = 122 bits (295), Expect = 8e-27
Identities = 65/170 (38%), Positives = 99/170 (58%)
Frame = +1
Query: 256 ALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXXXX 435
A+ + + + M D+ V V+GE+V + TRGL +++G +RV +TPI+E
Sbjct: 12 AMYEGLRDAMREDKTVVVIGEDVDR--SIIGATRGLIEEFGPERVRNTPISEATFVGACI 69
Query: 436 XXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASSVAAQ 615
L+P+ + M +F A+D + N AAK YMS G V +PIV+ G + S AAQ
Sbjct: 70 GASAAGLRPVVDLMVGSFFYVAMDQVANQAAKLPYMSGGQVSLPIVYFTATGPSGSAAAQ 129
Query: 616 HSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVMLEDEIMYG 765
HS+ + GLK++MP S DAKGL+ +AIRDP+PV+ L+D ++ G
Sbjct: 130 HSENPHPMLMNVAGLKIVMPSSPCDAKGLMISAIRDPNPVIYLQDAVLGG 179
>UniRef50_A0HHH4 Cluster: Transketolase, central region; n=2;
Bacteria|Rep: Transketolase, central region - Comamonas
testosteroni KF-1
Length = 334
Score = 122 bits (294), Expect = 1e-26
Identities = 61/181 (33%), Positives = 99/181 (54%)
Frame = +1
Query: 220 KALASKPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDT 399
+A ++ ++ A+N A+ + + + GE+VA+ G + VT+ L K++G RV DT
Sbjct: 5 QATSTLALSYAKAINAALSRALTHMPETLLFGEDVAKPGGVFGVTKDLQKEFGSARVFDT 64
Query: 400 PITEXXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFR 579
PI+E ++PI E M +FS+ A+D I+N AA Y+SAG + P+ R
Sbjct: 65 PISETAMLGTAVGAAMCGMRPIVEIMWIDFSLVAMDQIVNQAANVRYVSAGKLQAPMTIR 124
Query: 580 GPNGAASSVAAQHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVMLEDEIM 759
GA AQHSQ A ++H PGL+V +P + +DA +L I DP +++E+ +
Sbjct: 125 TQQGALPGSCAQHSQNLEAMFAHVPGLRVGLPATVQDAYDMLLTGIACNDPSLIIENRGL 184
Query: 760 Y 762
Y
Sbjct: 185 Y 185
>UniRef50_Q4DEQ0 Cluster: 2-oxoisovalerate dehydrogenase beta
subunit, mitochondrial, putative; n=2; Trypanosoma
cruzi|Rep: 2-oxoisovalerate dehydrogenase beta subunit,
mitochondrial, putative - Trypanosoma cruzi
Length = 368
Score = 121 bits (291), Expect = 2e-26
Identities = 61/170 (35%), Positives = 90/170 (52%), Gaps = 1/170 (0%)
Frame = +1
Query: 256 ALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXXXX 435
A+N A+D + RDEK V GE+VA + G ++ T L KKYG +RV D+P++E
Sbjct: 54 AINSALDLALSRDEKTVVFGEDVA-FGGVFRCTLNLSKKYGSQRVFDSPLSEQGLVGFAI 112
Query: 436 XXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVP-IVFRGPNGAASSVAA 612
KPI E ++ A D I+N AAK + S G +V R P+ A
Sbjct: 113 GMASAGWKPIAEVQFADYIFPAFDQIVNEAAKMRFRSGGHFHCGGLVIRSPSSAVGHGGL 172
Query: 613 QHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVMLEDEIMY 762
HSQ +++HC G+K++MP + DAKGLL + + DP + E + +Y
Sbjct: 173 YHSQSVEGFFNHCAGIKIVMPSTPSDAKGLLLQCVEEEDPCIFFEPKRLY 222
>UniRef50_Q479Q1 Cluster: Transketolase, central
region:Transketolase, C-terminal precursor; n=2;
Rhodocyclaceae|Rep: Transketolase, central
region:Transketolase, C-terminal precursor -
Dechloromonas aromatica (strain RCB)
Length = 337
Score = 120 bits (290), Expect = 3e-26
Identities = 66/170 (38%), Positives = 89/170 (52%)
Frame = +1
Query: 241 VTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXX 420
+T+ DA+ A+ EEM RD KV GE +A L ++G RV +TP+ E
Sbjct: 4 LTLNDAIGLALAEEMRRDHKVIAFGEGIATK------RHELVTEFGALRVRNTPLAEGII 57
Query: 421 XXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAAS 600
L+P+ + + F A+D ++NSA K YMS G P+V GA
Sbjct: 58 AGTAAGAAAGGLRPVADLLFAPFLCYAMDELVNSAGKLRYMSGGQFSFPLVALAMTGAGW 117
Query: 601 SVAAQHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVMLED 750
V AQH+ AW+ H PGLKV+MP + DA+ LLK AIRD +PVV L D
Sbjct: 118 GVGAQHNHNVEAWFVHSPGLKVVMPSNPADARALLKTAIRDDNPVVFLLD 167
>UniRef50_P75391 Cluster: Pyruvate dehydrogenase E1 component
subunit beta; n=23; Mollicutes|Rep: Pyruvate
dehydrogenase E1 component subunit beta - Mycoplasma
pneumoniae
Length = 327
Score = 119 bits (286), Expect = 9e-26
Identities = 63/170 (37%), Positives = 83/170 (48%)
Frame = +1
Query: 253 DALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXXX 432
+AL A+D +ERD V + G++ G ++ T+GL KKYG++RV D PI E
Sbjct: 11 EALGNAMDLALERDPNVVLYGQDAGFEGGVFRATKGLQKKYGEERVWDCPIAEAAMAGIG 70
Query: 433 XXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASSVAA 612
LKPI E FS A+ I AA+ S G PI+ R P G
Sbjct: 71 VGAAIGGLKPIVEIQFSGFSFPAMFQIFTHAARIRNRSRGVYTCPIIVRMPMGGGIKALE 130
Query: 613 QHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVMLEDEIMY 762
HS+ A Y GLK +MP + D KGL AA+ PDPVV E + +Y
Sbjct: 131 HHSETLEAIYGQIAGLKTVMPSNPYDTKGLFLAAVESPDPVVFFEPKKLY 180
>UniRef50_A1RJV5 Cluster: Transketolase, central region; n=18;
cellular organisms|Rep: Transketolase, central region -
Shewanella sp. (strain W3-18-1)
Length = 325
Score = 118 bits (284), Expect = 2e-25
Identities = 60/170 (35%), Positives = 93/170 (54%), Gaps = 1/170 (0%)
Frame = +1
Query: 256 ALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXXXX 435
A+N+A+ M+ DE++ V GE+V + G ++ T GL +K+G R +TP+TE
Sbjct: 9 AVNEALSIAMQADERMVVFGEDVGHFGGVFRATSGLQEKFGRARCFNTPLTEQGIAGFAN 68
Query: 436 XXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPV-PIVFRGPNGAASSVAA 612
+ + E ++ A D I+N +AK Y S V +VFR P G +
Sbjct: 69 GLASNGMTAVAEIQFADYIFPAFDQIVNESAKFRYRSGNEFDVGGLVFRTPYGGGIAGGH 128
Query: 613 QHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVMLEDEIMY 762
HSQ A+++ PGLKV++P + E AKGLL A+IRD +PV+ E + +Y
Sbjct: 129 YHSQSPEAYFTQTPGLKVVVPRNPEQAKGLLLASIRDKNPVIFFEPKRLY 178
>UniRef50_A5V556 Cluster: Transketolase domain protein; n=1;
Sphingomonas wittichii RW1|Rep: Transketolase domain
protein - Sphingomonas wittichii RW1
Length = 330
Score = 118 bits (283), Expect = 2e-25
Identities = 63/169 (37%), Positives = 96/169 (56%)
Frame = +1
Query: 244 TVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXX 423
T +A+ QA EEM RDE+VF++GE++ + T G +G +RV DTPI+E
Sbjct: 5 TFLEAIRQAQYEEMTRDERVFIMGEDIIC--NVFGTTTGFVDAFGTERVRDTPISENGFI 62
Query: 424 XXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASS 603
++PI + +F A+D I++ AK+ Y+ G +P+V R +S
Sbjct: 63 GAAGGAAMVGMRPIVDATISSFLYPAMDQIMSIIAKSRYIYGGQARLPLVIRSCLFYGNS 122
Query: 604 VAAQHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVMLED 750
AAQHS + + + PGLK+++P +A D KG+LKAA+RD DPV+ ED
Sbjct: 123 NAAQHSDRNYSMFMNVPGLKIMVPSNAHDMKGMLKAAVRDDDPVLCFED 171
>UniRef50_A0JY24 Cluster: Transketolase, central region; n=2;
cellular organisms|Rep: Transketolase, central region -
Arthrobacter sp. (strain FB24)
Length = 354
Score = 118 bits (283), Expect = 2e-25
Identities = 60/174 (34%), Positives = 90/174 (51%)
Frame = +1
Query: 241 VTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXX 420
++++ ALN+A+DE + + K V GE+ + G +++T GL KYG RV DTP+ E
Sbjct: 24 LSMQQALNRALDEVLAGNPKSLVFGEDCGRLGGVFRITDGLQAKYGPGRVFDTPLAESGI 83
Query: 421 XXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAAS 600
PI E F+ AI+ I+ A+ Y S GT+P+PI R P+
Sbjct: 84 LGMSVGLAMAGFHPIPEVQFDGFAYPAINQIVCQIARMNYRSRGTMPMPITLRVPSFGGI 143
Query: 601 SVAAQHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVMLEDEIMY 762
H + A ++H PGLKV+ P + +A LLK A PDPV+ +E + Y
Sbjct: 144 RAPEHHGESLEALFAHVPGLKVVSPSNPHEAYHLLKYAATRPDPVIFMEPKSRY 197
>UniRef50_P0A0A3 Cluster: Pyruvate dehydrogenase E1 component
subunit beta; n=33; cellular organisms|Rep: Pyruvate
dehydrogenase E1 component subunit beta - Staphylococcus
aureus
Length = 325
Score = 118 bits (283), Expect = 2e-25
Identities = 59/174 (33%), Positives = 87/174 (50%)
Frame = +1
Query: 241 VTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXX 420
+T+ A+N A+ E++ D+ V + GE+V G ++VT GL K++G+ RV DTP+ E
Sbjct: 4 MTMVQAINDALKTELKNDQDVLIFGEDVGVNGGVFRVTEGLQKEFGEDRVFDTPLAESGI 63
Query: 421 XXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAAS 600
+P+ E F + D I A+T + S GT P+ R P G
Sbjct: 64 GGLAMGLAVEGFRPVMEVQFLGFVFEVFDAIAGQIARTRFRSGGTKTAPVTIRSPFGGGV 123
Query: 601 SVAAQHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVMLEDEIMY 762
H+ + PGLKV++P DAKGLL ++IR DPVV LE +Y
Sbjct: 124 HTPELHADNLEGILAQSPGLKVVIPSGPYDAKGLLISSIRSNDPVVYLEHMKLY 177
>UniRef50_Q023C4 Cluster: Pyruvate dehydrogenase; n=1; Solibacter
usitatus Ellin6076|Rep: Pyruvate dehydrogenase -
Solibacter usitatus (strain Ellin6076)
Length = 397
Score = 117 bits (281), Expect = 4e-25
Identities = 68/180 (37%), Positives = 92/180 (51%), Gaps = 1/180 (0%)
Frame = +1
Query: 226 LASKPVTVRDALNQAIDEEMERDEKVFVLGEEVAQ-YDGAYKVTRGLWKKYGDKRVIDTP 402
LA KPVT+ DA+N + EEMER+ K+ + GE++A G + VTRGL RV + P
Sbjct: 68 LAEKPVTMIDAINHGLREEMERNPKIVMWGEDIADPKGGVFGVTRGLSSALPG-RVFNAP 126
Query: 403 ITEXXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRG 582
+ E KPI E +++ A + N A + S GT P+V R
Sbjct: 127 LAEASIAGVAAGMAIAGYKPIIEIQFADYTWPAFMQLRNEIATVRWRSQGTWNCPVVVRI 186
Query: 583 PNGAASSVAAQHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVMLEDEIMY 762
GA HS C ++H PG +VL P AEDAKGL+K A R DPV+ LE + +Y
Sbjct: 187 AAGAYIKGGPWHSACVEGVFAHIPGWRVLFPSCAEDAKGLIKMAARLEDPVIFLEHKGLY 246
>UniRef50_P21882 Cluster: Pyruvate dehydrogenase E1 component
subunit beta; n=41; cellular organisms|Rep: Pyruvate
dehydrogenase E1 component subunit beta - Bacillus
subtilis
Length = 325
Score = 117 bits (281), Expect = 4e-25
Identities = 59/174 (33%), Positives = 87/174 (50%)
Frame = +1
Query: 241 VTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXX 420
+T+ A+ A+ E++ DE V V GE+V G ++ T GL K++G+ RV DTP+ E
Sbjct: 4 MTMIQAITDALRTELKNDENVLVFGEDVGVNGGVFRATEGLQKEFGEDRVFDTPLAESGI 63
Query: 421 XXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAAS 600
+P+ E F F + +D + A+ Y S G P+ R P G
Sbjct: 64 GGLALGLGLNGFRPVMEIQFFGFVYEVMDSVSGQMARMRYRSGGRWTSPVTIRSPFGGGV 123
Query: 601 SVAAQHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVMLEDEIMY 762
H+ + PG+KV++P + DAKGLL +AIRD DPVV LE +Y
Sbjct: 124 HTPELHADSLEGLVAQQPGIKVVIPSTPYDAKGLLISAIRDNDPVVFLEHMKLY 177
>UniRef50_UPI000155C0B5 Cluster: PREDICTED: similar to pyruvate
dehydrogenase (lipoamide) beta, partial; n=1;
Ornithorhynchus anatinus|Rep: PREDICTED: similar to
pyruvate dehydrogenase (lipoamide) beta, partial -
Ornithorhynchus anatinus
Length = 141
Score = 115 bits (277), Expect = 1e-24
Identities = 51/57 (89%), Positives = 57/57 (100%)
Frame = +1
Query: 241 VTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITE 411
VTVRDALNQA+DEE+ERDEKVF+LGEEVAQYDGAYKV+RGLWKKYGDKR+IDTPI+E
Sbjct: 1 VTVRDALNQALDEELERDEKVFLLGEEVAQYDGAYKVSRGLWKKYGDKRIIDTPISE 57
>UniRef50_A4XF90 Cluster: Transketolase domain protein; n=1;
Novosphingobium aromaticivorans DSM 12444|Rep:
Transketolase domain protein - Novosphingobium
aromaticivorans (strain DSM 12444)
Length = 327
Score = 111 bits (268), Expect = 1e-23
Identities = 59/171 (34%), Positives = 93/171 (54%)
Frame = +1
Query: 226 LASKPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPI 405
++S+ + A+ + EEM RD+ +F++G+ V G + + +GL ++G+ RV+D I
Sbjct: 1 MSSETMGYNAAMGLGLVEEMRRDDSIFIMGQGVVT-GGWFGMEKGLVAEFGNDRVLDCGI 59
Query: 406 TEXXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGP 585
E +KP+ +F++ A D I + AK YM VP+ V P
Sbjct: 60 AEAFEAGLAAGAAIAGMKPVINMGFGDFALIAGDEIYHKLAKWRYMHGLDVPMTAVIIFP 119
Query: 586 NGAASSVAAQHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVV 738
GA +HS C H PGLKV++P +AEDAKGL+KAA+R+P+PV+
Sbjct: 120 IGAMGGAGPEHSSCTEVLGMHFPGLKVVVPSTAEDAKGLMKAALREPNPVL 170
>UniRef50_Q020J5 Cluster: Dehydrogenase, E1 component; n=1;
Solibacter usitatus Ellin6076|Rep: Dehydrogenase, E1
component - Solibacter usitatus (strain Ellin6076)
Length = 697
Score = 111 bits (266), Expect = 2e-23
Identities = 64/202 (31%), Positives = 97/202 (48%), Gaps = 13/202 (6%)
Frame = +1
Query: 205 SFATSKALASKPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYD------------GAYK 348
+F P+T+ D +N + EEM R+ + V GE+VA G +K
Sbjct: 346 AFHAEPRFQGAPMTMVDLINATLREEMRRNPDILVFGEDVADASREQNLTEVKGKGGVFK 405
Query: 349 VTRGLWKKYGDKRVIDTPITEXXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAA 528
VT GL ++G +R + PI E LKP+ E F++ A+ + + A
Sbjct: 406 VTHGLQSEFGARRAFNAPIAEAAIVGRAIGMAARGLKPVAEIQFFDYIWPAMMQLRDELA 465
Query: 529 KTFYMSAGTVPVPIVFRGP-NGAASSVAAQHSQCFGAWYSHCPGLKVLMPYSAEDAKGLL 705
+ S G P + R P G + A HSQC + ++H PGL+V+ P +A DA GLL
Sbjct: 466 TMRWRSNGAFSAPAIIRVPIGGYLNGGAIYHSQCGESIFTHIPGLRVVFPSNAADACGLL 525
Query: 706 KAAIRDPDPVVMLEDEIMYGIP 771
+ A+R DPV+ LE + +Y P
Sbjct: 526 RTALRSDDPVLFLEHKRLYREP 547
>UniRef50_Q83X27 Cluster: Probable pyruvate dehydrogenase
beta-subunit; n=1; Streptomyces rochei|Rep: Probable
pyruvate dehydrogenase beta-subunit - Streptomyces
rochei (Streptomyces parvullus)
Length = 344
Score = 110 bits (264), Expect = 4e-23
Identities = 62/178 (34%), Positives = 88/178 (49%)
Frame = +1
Query: 235 KPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEX 414
+ +T A+++A + ME D + + G+ V Y G Y T + ++G RVID P E
Sbjct: 2 RSLTYSQAISEATVQCMEADPAIVLAGQSVDDYKGVYGTTGEAFARFGSARVIDIPNGEN 61
Query: 415 XXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGA 594
L+P+ +F A+D +IN AAK YM G VP+V RG G
Sbjct: 62 AFAGIAIGAATMGLRPLLVHTRDDFMFLAMDALINLAAKWRYMYGGKRGVPVVSRGVVGR 121
Query: 595 ASSVAAQHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVMLEDEIMYGI 768
A HSQ + + H PGL V P S DAKGLL A++ PVV+LE+ +Y +
Sbjct: 122 GWGQGATHSQSLQSLFGHFPGLHVATPASPADAKGLLVTALQGDTPVVLLENRGLYDL 179
>UniRef50_A7CXF2 Cluster: Transketolase central region; n=1;
Opitutaceae bacterium TAV2|Rep: Transketolase central
region - Opitutaceae bacterium TAV2
Length = 398
Score = 109 bits (262), Expect = 8e-23
Identities = 57/182 (31%), Positives = 92/182 (50%)
Frame = +1
Query: 217 SKALASKPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVID 396
S A +T+ A+N A+ + + + +LG+++ Y GA+KVT L + +G RV +
Sbjct: 67 SLCTAPAHLTMAQAINAALRKILAERPESLLLGQDIGVYGGAFKVTENLLRDFGRTRVFN 126
Query: 397 TPITEXXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVF 576
TP+ E +PI EF +FS +A+ I +AA Y + VP+V+
Sbjct: 127 TPLAESACTGYATGLALGGYRPIEEFQFADFSTEAVTQITQNAATYHYRTGAAAKVPVVY 186
Query: 577 RGPNGAASSVAAQHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVMLEDEI 756
R P G +V + HSQ + PG+K L P + +DA L AA D +PV++ E +
Sbjct: 187 RFPCGGGITVGSFHSQELETLFLAFPGIKALYPSTPQDAFNALLAAYEDDNPVILFEHKA 246
Query: 757 MY 762
+Y
Sbjct: 247 LY 248
>UniRef50_A0M1U4 Cluster: 2-oxoisovalerate dehydrogenase E1
component subunits alpha and beta; n=18;
Bacteroidetes|Rep: 2-oxoisovalerate dehydrogenase E1
component subunits alpha and beta - Gramella forsetii
(strain KT0803)
Length = 685
Score = 109 bits (262), Expect = 8e-23
Identities = 56/170 (32%), Positives = 87/170 (51%)
Frame = +1
Query: 253 DALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXXX 432
DA++QA+ E +++ E + ++G+++A Y G +K+T G +++G R+ +TPI E
Sbjct: 372 DAISQALKESVKKHENLVLMGQDIADYGGVFKITEGFVEEFGKDRIRNTPICESAIVGAA 431
Query: 433 XXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASSVAA 612
+K + E +F + I+N AK Y V V R P G
Sbjct: 432 MGLSINGMKAMVEMQFSDFVSSGFNPIVNYLAKVKYRWDQNADV--VLRMPCGGGVGAGP 489
Query: 613 QHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVMLEDEIMY 762
HSQ AW++ PGLKV+ P DAKGLL A DP+PV+ E + +Y
Sbjct: 490 FHSQTNEAWFTKVPGLKVIYPAFPYDAKGLLNTAFNDPNPVLFFEHKGLY 539
>UniRef50_Q83DL8 Cluster: Dehydrogenase, E1 component, beta subunit;
n=9; Proteobacteria|Rep: Dehydrogenase, E1 component,
beta subunit - Coxiella burnetii
Length = 353
Score = 108 bits (259), Expect = 2e-22
Identities = 56/170 (32%), Positives = 87/170 (51%)
Frame = +1
Query: 259 LNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXXXXX 438
+N A+ + M+ D V G + + T GL +++G+ RV D P E
Sbjct: 10 INAALRKAMQIDPSVLCYGLGINDSARIFGTTTGLVEEFGEDRVFDMPTAENAMTGVGIG 69
Query: 439 XXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASSVAAQH 618
+P+ +F++ ++D IIN AAK + + AGT+PVP+ R G H
Sbjct: 70 LAINGFRPVLSHCRLDFALLSLDQIINGAAKWYSLFAGTMPVPLTIRAIVGRGWGQGPTH 129
Query: 619 SQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVMLEDEIMYGI 768
Q A ++H PGLKV+MP AEDA GLL ++I D +PV+ +E ++ I
Sbjct: 130 CQSLQACFAHIPGLKVVMPSLAEDAYGLLLSSIFDDNPVIFIEHRWLHNI 179
>UniRef50_A4L2Q6 Cluster: E1 component beta subunit; n=16;
Bacilli|Rep: E1 component beta subunit - Lactobacillus
reuteri
Length = 325
Score = 107 bits (258), Expect = 2e-22
Identities = 56/169 (33%), Positives = 84/169 (49%)
Frame = +1
Query: 256 ALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXXXX 435
A+ + ID + D K V GE+V + G ++ T GL +KYG RV TP+ E
Sbjct: 9 AITEGIDIALAEDPKTLVFGEDVGKNGGVFRATNGLQEKYGVDRVFSTPLAESGILGMSM 68
Query: 436 XXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASSVAAQ 615
+P+ E F+ +A+D I ++ + GT PI R P G + A
Sbjct: 69 GLAVTGWRPVPEIQFMGFTFEAMDSIAAQMSRIRFQYNGTKHAPITIRTPYGGGTHTAEL 128
Query: 616 HSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVMLEDEIMY 762
H ++ PGL+V+ P SA DAKGL+ +AI + DPV+ LE+ +Y
Sbjct: 129 HGDDLENFFVGIPGLRVVAPSSAYDAKGLIISAIENNDPVLFLENLRLY 177
>UniRef50_A4XHV5 Cluster: Transketolase, central region; n=3;
Bacteria|Rep: Transketolase, central region -
Caldicellulosiruptor saccharolyticus (strain ATCC 43494 /
DSM 8903)
Length = 823
Score = 107 bits (257), Expect = 3e-22
Identities = 63/179 (35%), Positives = 95/179 (53%)
Frame = +1
Query: 232 SKPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITE 411
+K +RDA+ +A+ ++ D + GE++ + GA+ V RGL + R+ +T I+E
Sbjct: 473 AKVFNLRDAIFEALIDKFYTDPTLISYGEDLRDWGGAFAVYRGLTESLPYHRLFNTSISE 532
Query: 412 XXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNG 591
+ + E M +F +A D I N AK MSAGT+ +P+V R G
Sbjct: 533 GAIVGSAVGYGMCGGRVVVEIMYCDFIGRAGDEIFNQLAKWQAMSAGTLKMPVVVRVSVG 592
Query: 592 AASSVAAQHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVMLEDEIMYGI 768
S AQHSQ + + SH PGLKV+ P + DAKGL+ AA+ DPV+ E + +Y I
Sbjct: 593 --SKYGAQHSQDWSSIVSHIPGLKVVFPATPYDAKGLMNAALSGTDPVIFFESQRLYDI 649
>UniRef50_Q6ABX8 Cluster: Pyruvate dehydrogenase E1 component
subunit beta; n=60; cellular organisms|Rep: Pyruvate
dehydrogenase E1 component subunit beta - Leifsonia xyli
subsp. xyli
Length = 337
Score = 105 bits (251), Expect = 2e-21
Identities = 51/169 (30%), Positives = 80/169 (47%)
Frame = +1
Query: 256 ALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXXXX 435
ALN + + + D KV +LGE+V G ++VT GL ++G RV+DTP+ E
Sbjct: 22 ALNAGLRQALVADPKVLILGEDVGPLGGVFRVTEGLQSEFGASRVVDTPLAEAGIVGTAI 81
Query: 436 XXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASSVAAQ 615
+P+ E F D I AK +G V +P+V R P+G
Sbjct: 82 GLAMRGYRPVVEIQFNGFVFPGFDQITTQLAKMANRHSGAVSMPVVIRIPHGGHIGAVEH 141
Query: 616 HSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVMLEDEIMY 762
H + A+++H GL+++ P + DA +++ AI DPV+ E Y
Sbjct: 142 HQEAPEAYFAHTAGLRIVAPSTPHDAYWMIQEAIASDDPVIFFEPMSRY 190
>UniRef50_P21953 Cluster: 2-oxoisovalerate dehydrogenase subunit
beta, mitochondrial precursor; n=84; cellular
organisms|Rep: 2-oxoisovalerate dehydrogenase subunit
beta, mitochondrial precursor - Homo sapiens (Human)
Length = 392
Score = 105 bits (251), Expect = 2e-21
Identities = 57/170 (33%), Positives = 84/170 (49%), Gaps = 1/170 (0%)
Frame = +1
Query: 256 ALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXXXX 435
++ A+D + +D + GE+VA + G ++ T GL KYG RV +TP+ E
Sbjct: 76 SVTSALDNSLAKDPTAVIFGEDVA-FGGVFRCTVGLRDKYGKDRVFNTPLCEQGIVGFGI 134
Query: 436 XXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPV-PIVFRGPNGAASSVAA 612
I E ++ A D I+N AAK Y S + R P G A
Sbjct: 135 GIAVTGATAIAEIQFADYIFPAFDQIVNEAAKYRYRSGDLFNCGSLTIRSPWGCVGHGAL 194
Query: 613 QHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVMLEDEIMY 762
HSQ A+++HCPG+KV++P S AKGLL + I D +P + E +I+Y
Sbjct: 195 YHSQSPEAFFAHCPGIKVVIPRSPFQAKGLLLSCIEDKNPCIFFEPKILY 244
>UniRef50_Q319T3 Cluster: Pyruvate dehydrogenase; n=1;
Prochlorococcus marinus str. MIT 9312|Rep: Pyruvate
dehydrogenase - Prochlorococcus marinus (strain MIT
9312)
Length = 329
Score = 104 bits (250), Expect = 2e-21
Identities = 59/176 (33%), Positives = 87/176 (49%)
Frame = +1
Query: 235 KPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEX 414
K T A+ A + ++ +VFV+G+ + + L K +G KR+IDTP++E
Sbjct: 2 KKFTYSTAILDAYNFLLKNYPEVFVIGQGLWSPWYVGNTMKDLDKNFGKKRIIDTPVSEA 61
Query: 415 XXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGA 594
+KPI +F M A+D IIN AAK YM G I RG
Sbjct: 62 AVTGAAVGASLNEMKPIVVHPRMDFMMYAMDPIINQAAKWSYMFGGQSSPSITIRGIINR 121
Query: 595 ASSVAAQHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVMLEDEIMY 762
AQHSQ + ++H PGLKV++P S DA+ LL A++ PV+ ++D +Y
Sbjct: 122 GGEQGAQHSQALHSLFAHIPGLKVVLPSSVADARDLLIASVLADQPVIYIDDRWLY 177
>UniRef50_Q5BSL1 Cluster: SJCHGC03862 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC03862 protein - Schistosoma
japonicum (Blood fluke)
Length = 91
Score = 104 bits (250), Expect = 2e-21
Identities = 46/74 (62%), Positives = 60/74 (81%)
Frame = +1
Query: 190 RLSRRSFATSKALASKPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWK 369
+L RS T+ ++ + +TVRDALN A+ EE+ERD+ V +LGEEVAQYDGAYK+T+GLWK
Sbjct: 17 QLCSRSIKTTSSVYTSKMTVRDALNSAMREELERDKDVIILGEEVAQYDGAYKITKGLWK 76
Query: 370 KYGDKRVIDTPITE 411
+GD RV+DTPITE
Sbjct: 77 TFGDSRVMDTPITE 90
>UniRef50_Q1IQR3 Cluster: Dehydrogenase, E1 component; n=1;
Acidobacteria bacterium Ellin345|Rep: Dehydrogenase, E1
component - Acidobacteria bacterium (strain Ellin345)
Length = 736
Score = 104 bits (249), Expect = 3e-21
Identities = 61/188 (32%), Positives = 95/188 (50%), Gaps = 15/188 (7%)
Frame = +1
Query: 244 TVRDALNQAIDEEMERDEKVFVLGEEVA-----QY---------DGAYKVTRGLWKKYGD 381
T+ D +N + +EM+RD ++ + GE+VA +Y G +K+T GL +YG
Sbjct: 397 TMADLINACLKDEMKRDPRIVIFGEDVADCSREEYLKQKQVKGKGGVFKLTSGLQMEYGA 456
Query: 382 KRVIDTPITEXXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVP 561
RV ++P+ E LKP+ E F++ A+ + N + S G
Sbjct: 457 DRVFNSPLAEANIVGRATGMAVRGLKPVVEIQFFDYIWPAMHQLRNELPVVRWRSNGAFS 516
Query: 562 VPIVFR-GPNGAASSVAAQHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVV 738
P V R G + A HSQC + ++H PG++V+ P +A DA GLL+ AIR DPV+
Sbjct: 517 SPAVIRVAIGGYLTGGAIYHSQCGESIFTHTPGMRVIFPSNALDANGLLRTAIRCDDPVL 576
Query: 739 MLEDEIMY 762
LE + +Y
Sbjct: 577 FLEHKRLY 584
>UniRef50_A7EW39 Cluster: Pyruvate dehydrogenase E1 component beta
subunit; n=16; Ascomycota|Rep: Pyruvate dehydrogenase E1
component beta subunit - Sclerotinia sclerotiorum 1980
Length = 403
Score = 103 bits (247), Expect = 5e-21
Identities = 56/179 (31%), Positives = 92/179 (51%), Gaps = 2/179 (1%)
Frame = +1
Query: 232 SKPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITE 411
+K + + ++N A+ + +DE V GE+V + G ++ + GL ++YG +RV +TP+ E
Sbjct: 76 TKRMNLFQSINDALSLALSKDETTMVFGEDVG-FGGVFRCSTGLAEQYGSERVFNTPLCE 134
Query: 412 XXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSA--GTVPVPIVFRGP 585
+K + E ++ A D ++N AAK Y G + R P
Sbjct: 135 QGIIGFAIGAAAEGMKAVAEIQFADYVYPAFDQLVNEAAKWRYRDGEYGRGLGGLTVRMP 194
Query: 586 NGAASSVAAQHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVMLEDEIMY 762
GA A HSQ + ++H PGL+V+MP S AKGLL +AI+ DP + +E + +Y
Sbjct: 195 CGAVGHGALYHSQSPESLFTHIPGLRVIMPRSPIQAKGLLLSAIQSSDPCIFMEPKALY 253
>UniRef50_A1G854 Cluster: Transketolase, central region; n=3;
Actinomycetales|Rep: Transketolase, central region -
Salinispora arenicola CNS205
Length = 321
Score = 101 bits (243), Expect = 2e-20
Identities = 59/168 (35%), Positives = 93/168 (55%), Gaps = 1/168 (0%)
Frame = +1
Query: 241 VTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXX 420
++ R ALN+A+ +E+ RDE+VF+LGE++ A VT GL K++G +RV DTP++E
Sbjct: 4 LSYRKALNRALADELARDEEVFLLGEDIRV--AASAVTAGLLKRFGPERVRDTPLSEQAF 61
Query: 421 XXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGP-NGAA 597
+P+ EF + I+N A K M+ G VP+ + P +G+
Sbjct: 62 TSFATGAAMAGARPVVEFQIPALLFLVFEQIVNHAHKFPLMTGGQCSVPVTYLVPGSGSR 121
Query: 598 SSVAAQHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVM 741
+ A QHS + ++H G+ ++P + DA GLL +AIR DPVV+
Sbjct: 122 TGWAGQHSDHPYSLFAHV-GVTTVVPATPADAYGLLVSAIRCDDPVVV 168
>UniRef50_Q2BFQ9 Cluster: Putative uncharacterized protein; n=1;
Bacillus sp. NRRL B-14911|Rep: Putative uncharacterized
protein - Bacillus sp. NRRL B-14911
Length = 668
Score = 100 bits (239), Expect = 5e-20
Identities = 58/172 (33%), Positives = 88/172 (51%), Gaps = 2/172 (1%)
Frame = +1
Query: 253 DALNQAIDEEMERDEKVFVLGEEVAQ-YDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXX 429
D+LN A+ E D V ++GE++ Y GA+KV++GL KY D RV+ TPI+E
Sbjct: 342 DSLNNALHELFNEDGDVLLIGEDLLDPYGGAFKVSKGLSTKYPD-RVLTTPISEGGILGL 400
Query: 430 XXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASSVA 609
LKPI E M +F D ++N A+K +M V VP+V R P G
Sbjct: 401 STGLAMRGLKPIAEIMFGDFLALGADQLLNHASKYQWMYNNKVEVPLVVRAPMGGKRGYG 460
Query: 610 AQHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLK-AAIRDPDPVVMLEDEIMY 762
HSQ + PGL V+ P + + LLK + ++ P++ +E++ +Y
Sbjct: 461 PTHSQSIEKMFFGIPGLTVVSPSNIHEPGELLKRSVLKHRSPLLFIENKALY 512
>UniRef50_A5ACP6 Cluster: Putative uncharacterized protein; n=1;
Vitis vinifera|Rep: Putative uncharacterized protein -
Vitis vinifera (Grape)
Length = 360
Score = 98.3 bits (234), Expect = 2e-19
Identities = 55/147 (37%), Positives = 83/147 (56%), Gaps = 7/147 (4%)
Frame = +1
Query: 151 ALKSSPAVLG---MLTR-LSRRSFATSKALASKP---VTVRDALNQAIDEEMERDEKVFV 309
+L SSP G ++T ++ ++ A++ + ASKP + + +AL + ++EEM+RD V V
Sbjct: 45 SLGSSPRSRGAQHLITNAVAAKADASATSTASKPGHELLLFEALREGLEEEMDRDPLVCV 104
Query: 310 LGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXXXXXXXXXXLKPICEFMTFNF 489
+GE+V Y G+YKVT+GL KYGD RV+DTPI E L+PI E M F
Sbjct: 105 MGEDVGHYGGSYKVTKGLAAKYGDLRVLDTPIAENSFTGMGIGAAMTGLRPIIEGMNMGF 164
Query: 490 SMQAIDHIINSAAKTFYMSAGTVPVPI 570
+ A + I N+ Y S G +P+
Sbjct: 165 LLLAFNQISNNCGMLHYTSGGQFKIPV 191
>UniRef50_A2TU24 Cluster: (Pyruvate) Oxoisovalerate Dehydrogenase
Alpha and Beta Fusion; n=6; cellular organisms|Rep:
(Pyruvate) Oxoisovalerate Dehydrogenase Alpha and Beta
Fusion - Dokdonia donghaensis MED134
Length = 693
Score = 97.9 bits (233), Expect = 2e-19
Identities = 54/175 (30%), Positives = 88/175 (50%), Gaps = 1/175 (0%)
Frame = +1
Query: 241 VTVRDALNQAIDEEMERDEKVFVLGEEVA-QYDGAYKVTRGLWKKYGDKRVIDTPITEXX 417
V + D A++E M + + + G++V + G ++ L +K+GD RV +TPI E
Sbjct: 357 VVMVDCALFAVEELMRKHPECLMYGQDVGGRLGGVFREAATLAQKFGDNRVFNTPIQEAF 416
Query: 418 XXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAA 597
LKPI E ++ ++ + +++ Y+S G PV ++ R P GA
Sbjct: 417 IVGSTVGMSAVGLKPIVEVQFADYIWPGLNQLFTEVSRSCYLSNGKWPVSMILRVPIGAY 476
Query: 598 SSVAAQHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVMLEDEIMY 762
S HS + ++ GLK+ P + D KGLLKAA DP+PVV+ E + +Y
Sbjct: 477 GSGGPYHSSSVESVVTNIRGLKIAYPSNGADLKGLLKAAYYDPNPVVIFEHKGLY 531
>UniRef50_A3BGZ8 Cluster: Putative uncharacterized protein; n=2;
Oryza sativa|Rep: Putative uncharacterized protein -
Oryza sativa subsp. japonica (Rice)
Length = 391
Score = 95.1 bits (226), Expect = 2e-18
Identities = 64/200 (32%), Positives = 93/200 (46%), Gaps = 22/200 (11%)
Frame = +1
Query: 229 ASKPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPIT 408
A K V + A+NQA+ ++ D + +V GE+V + G ++ T GL ++G RV +TP+
Sbjct: 46 AGKEVNLFTAINQALHIALDTDPRSYVFGEDVG-FGGVFRCTTGLADRFGRNRVFNTPLC 104
Query: 409 EXXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDH---------------------IINSA 525
E + I E ++ A D I+N A
Sbjct: 105 EQGIAGFAVGLAAMGNRAIAEIQFADYIFPAFDQACLRLDQCFVPTYLYIQLLVQIVNEA 164
Query: 526 AKTFYMSAGTVPVP-IVFRGPNGAASSVAAQHSQCFGAWYSHCPGLKVLMPYSAEDAKGL 702
AK Y S + R P GA HSQ A++ H PGLKV++P S +AKGL
Sbjct: 165 AKFRYRSGNEFNCGGLTIRSPYGAVGHGGHYHSQSPEAFFCHVPGLKVIIPRSPREAKGL 224
Query: 703 LKAAIRDPDPVVMLEDEIMY 762
L A+IRDP+PVV E + +Y
Sbjct: 225 LLASIRDPNPVVFFEPKWLY 244
>UniRef50_Q7N3C2 Cluster: Similar to 3-methyl-2-oxobutanoate
dehydrogenase; n=1; Photorhabdus luminescens subsp.
laumondii|Rep: Similar to 3-methyl-2-oxobutanoate
dehydrogenase - Photorhabdus luminescens subsp.
laumondii
Length = 650
Score = 94.3 bits (224), Expect = 3e-18
Identities = 71/215 (33%), Positives = 105/215 (48%), Gaps = 4/215 (1%)
Frame = +1
Query: 130 SDIIFKMALKSSPAVLGMLTRLSRRSFATSKALASKPVTVR--DALNQAIDEEMERDEKV 303
+D I K S G T+L RS +T L S+ +R A+N+A E ME D+ +
Sbjct: 277 NDAIRKAKQARSSPFYGAETQLQSRS-STFHPLPSQGSKIRLSRAINKAFLEIMELDKNI 335
Query: 304 FVLGEEV-AQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXXXXXXXXXXLKPICEFMT 480
+GE+V A Y GA+K++ GL + ++ VI+TPI+E P E M
Sbjct: 336 LFIGEDVKAPYGGAFKISDGLSDSFPEQ-VINTPISESAIVGIGCGLAMHGYCPFVEIMF 394
Query: 481 FNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASSVAAQHSQCFGAWYSHCPGL 660
+F A D I+N AAK M V VP+V R P GA HSQ + PGL
Sbjct: 395 GDFLTLAFDQILNHAAKFRDMYNDQVKVPLVIRTPMGAGRGYGPTHSQTLEKHFMGIPGL 454
Query: 661 KVLMPYSAEDAKGLLKA-AIRDPDPVVMLEDEIMY 762
+L + D + K A ++ PV+++E++I+Y
Sbjct: 455 TILAINNLIDPAIVYKTLAKQEEGPVLLIENKILY 489
>UniRef50_A3SJ75 Cluster: 2-oxoisovalerate dehydrogenase beta
subunit; n=1; Roseovarius nubinhibens ISM|Rep:
2-oxoisovalerate dehydrogenase beta subunit -
Roseovarius nubinhibens ISM
Length = 746
Score = 93.5 bits (222), Expect = 5e-18
Identities = 53/166 (31%), Positives = 86/166 (51%), Gaps = 1/166 (0%)
Frame = +1
Query: 253 DALNQAIDEEMERDEKVFVLGEEVAQYDGAYK-VTRGLWKKYGDKRVIDTPITEXXXXXX 429
D +++ + ME+ + +FVLGE+V + G TRG+ +++ D R++ TPI E
Sbjct: 418 DVISEVMLRNMEKFDGLFVLGEDVHRLRGGTAGATRGIAERFPD-RLLGTPICENGFTGM 476
Query: 430 XXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASSVA 609
+P+ E M +FS+ A D + N AK +M G PVP+V R +
Sbjct: 477 ALGAALNGARPVVEIMYPDFSLVAADQLFNQIAKVRHMFGGDFPVPVVVRSRVTQGTGYG 536
Query: 610 AQHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVMLE 747
+QHS ++ PG +V+ P + D GL+ AAI DPV+++E
Sbjct: 537 SQHSMDASGLFTLYPGWRVVAPSTPHDYIGLMNAAIACDDPVLVVE 582
>UniRef50_Q8YDW3 Cluster: 2-OXOISOVALERATE DEHYDROGENASE BETA
SUBUNIT; n=10; Bacteria|Rep: 2-OXOISOVALERATE
DEHYDROGENASE BETA SUBUNIT - Brucella melitensis
Length = 729
Score = 86.2 bits (204), Expect = 8e-16
Identities = 54/172 (31%), Positives = 82/172 (47%), Gaps = 2/172 (1%)
Frame = +1
Query: 253 DALNQAIDEEMERDEKVFVLGEEVAQYDGAYK-VTRGLWKKYGDKRVIDTPITEXXXXXX 429
D + + ME DE+V VLGE+V + G TRGL Y D RV+ TPI+E
Sbjct: 403 DTVADVMARRMETDERVVVLGEDVHRLKGGTNGATRGLSADYPD-RVLGTPISENAFTGI 461
Query: 430 XXXXXXXX-LKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASSV 606
+ P+ EFM +F A D + N K +M G +P+V R +
Sbjct: 462 AGGMAADGRVLPVIEFMYPDFMWVAADQVFNQIGKARHMFGGDSDMPVVLRTKVAMGTGY 521
Query: 607 AAQHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVMLEDEIMY 762
+QHS ++ PG +++ P + D GL+ +A+ DPV++LE +Y
Sbjct: 522 GSQHSMDPAGIFATAPGWRIVAPSTPFDYVGLMNSALLCRDPVLVLEHVDLY 573
>UniRef50_Q9K3H1 Cluster: Putative pyruvate dehydrogenase beta
subunit; n=1; Streptomyces coelicolor|Rep: Putative
pyruvate dehydrogenase beta subunit - Streptomyces
coelicolor
Length = 337
Score = 84.6 bits (200), Expect = 2e-15
Identities = 51/173 (29%), Positives = 84/173 (48%), Gaps = 1/173 (0%)
Frame = +1
Query: 247 VRDALNQAIDEEMERDEKVFVLGEEVAQ-YDGAYKVTRGLWKKYGDKRVIDTPITEXXXX 423
V + LN A+ + +++GE+VA Y GA+KVTRGL ++ D RV+ +P++E
Sbjct: 7 VAENLNSALHHLLGAHPGTYLIGEDVADPYGGAFKVTRGLSDRFPD-RVLSSPLSEGGIA 65
Query: 424 XXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASS 603
+ + E M +F+ A D ++N AAK+ M VP+ +V R P G
Sbjct: 66 GVGAGLALAGNRSVVEMMFSDFAALAFDPLLNFAAKSVSMYGRRVPMSMVVRCPTGGNRG 125
Query: 604 VAAQHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVMLEDEIMY 762
HSQ + P L + D + +L A + +P V+ ED+++Y
Sbjct: 126 YGPTHSQSLQKHFLGIPSLHLREVSPFHDNRRVLTAMLDREEPGVLFEDKVLY 178
>UniRef50_Q8YDG0 Cluster: 2-OXOISOVALERATE DEHYDROGENASE BETA
SUBUNIT; n=3; Brucella|Rep: 2-OXOISOVALERATE
DEHYDROGENASE BETA SUBUNIT - Brucella melitensis
Length = 725
Score = 84.6 bits (200), Expect = 2e-15
Identities = 52/170 (30%), Positives = 80/170 (47%), Gaps = 1/170 (0%)
Frame = +1
Query: 256 ALNQAIDEEMERDEKVFVLGEEVAQYDGAYK-VTRGLWKKYGDKRVIDTPITEXXXXXXX 432
A + + ME+D + V+GE+V ++ G TR + + D RV+ PI E
Sbjct: 407 AASDVLGRAMEKDPTIIVIGEDVHRFAGGVSGFTRNALELFPD-RVLAMPIAENGFTGVV 465
Query: 433 XXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASSVAA 612
L+P+ E M +F A D I N +K +M PVPIV R + +
Sbjct: 466 LGAALRGLRPVVEIMFGDFCFVAADQIANGISKVRHMFGDGFPVPIVMRVRVSPHTGYGS 525
Query: 613 QHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVMLEDEIMY 762
QHS A + PG +V+ P +A D GL+ +A++ DPV ++E Y
Sbjct: 526 QHSGDPSALFGMFPGWRVVSPTNAFDYIGLMNSALKSDDPVAVIEHVEFY 575
>UniRef50_Q00TN9 Cluster: Pyruvate dehydrogenase E1 component beta;
n=3; Ostreococcus|Rep: Pyruvate dehydrogenase E1
component beta - Ostreococcus tauri
Length = 835
Score = 83.4 bits (197), Expect = 6e-15
Identities = 55/179 (30%), Positives = 85/179 (47%), Gaps = 4/179 (2%)
Frame = +1
Query: 220 KALASKP--VTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVI 393
+A+ + P +++ DA+N AI EEM RD E++ Q +Y + + +G R
Sbjct: 496 RAMCTDPRGISIGDAVNLAILEEMLRDPTTVAHAEDL-QAGSSYNIPANTQQAFGTLRAA 554
Query: 394 DTPITEXXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIV 573
D I E +PI E M NF + + + +SA T+ + G +P+
Sbjct: 555 DEIIDEGHFMGKALGEAMNGYRPIVELMNANFGIYGMAEL-SSAGNTYATTGGQFKMPMT 613
Query: 574 FRGPNGAA--SSVAAQHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVML 744
G G A S+ A+HSQ F A+ PGLK+ ++A GL K+ IRD P V+L
Sbjct: 614 VIGAGGTAPNQSLGAEHSQPFHAYIMGIPGLKICSASKPQEAYGLAKSMIRDNGPGVLL 672
>UniRef50_Q2WB98 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
complex; n=1; Magnetospirillum magneticum AMB-1|Rep:
Pyruvate/2-oxoglutarate dehydrogenase complex -
Magnetospirillum magneticum (strain AMB-1 / ATCC 700264)
Length = 647
Score = 83.0 bits (196), Expect = 8e-15
Identities = 52/172 (30%), Positives = 78/172 (45%), Gaps = 2/172 (1%)
Frame = +1
Query: 259 LNQAIDEEMERDEKVFVLGEEVAQ-YDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXXXX 435
+ +D M D+++ +LGE++ Y GA+KVT GL Y RV +TPI+E
Sbjct: 326 IRAGLDAAMAADDRLLLLGEDICSPYGGAFKVTSGLSDSYPG-RVFNTPISEAGLVGVGA 384
Query: 436 XXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASSVAAQ 615
+ + E M +F D +IN AAK M V VP++ R P G
Sbjct: 385 GLALAGRRVVAEIMFGDFLTLVADQLINHAAKFTQMYGEDVEVPLLVRTPMGGRRGYGPT 444
Query: 616 HSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRD-PDPVVMLEDEIMYGI 768
HSQ + PGL VL + DA I P +++E+++ YG+
Sbjct: 445 HSQSLETHFFGVPGLTVLAIHHRMDAAAFYARLIATAKTPHLIIENKVAYGV 496
>UniRef50_A6W004 Cluster: Transketolase domain protein; n=6;
Proteobacteria|Rep: Transketolase domain protein -
Marinomonas sp. MWYL1
Length = 701
Score = 81.8 bits (193), Expect = 2e-14
Identities = 48/164 (29%), Positives = 78/164 (47%)
Frame = +1
Query: 256 ALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXXXX 435
A+ + +D E+ + KV V GE+V G + T GL +K+G RV DT ++E
Sbjct: 386 AIRKTLDYELATNPKVMVFGEDVGPKGGVHGATLGLNEKFGGDRVFDTSLSEEGIIGRSV 445
Query: 436 XXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASSVAAQ 615
L P+ E ++ A + + ++ + + P+V R P G A
Sbjct: 446 GLALSGLMPVPEIQFRKYAEPAAEQLSDTGIMR-WRTNNQFAAPMVVRIPGGFARRGDPW 504
Query: 616 HSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVMLE 747
HS ++H G ++ MP +AEDA GLL+ A+RD +P + E
Sbjct: 505 HSMSDEVEWAHKVGWQLAMPSNAEDAVGLLRFALRDNNPTIFFE 548
>UniRef50_A6FZ18 Cluster: 2-oxoisovalerate dehydrogenase, E1
component, alpha and beta subunit; n=1; Plesiocystis
pacifica SIR-1|Rep: 2-oxoisovalerate dehydrogenase, E1
component, alpha and beta subunit - Plesiocystis
pacifica SIR-1
Length = 757
Score = 78.2 bits (184), Expect = 2e-13
Identities = 44/175 (25%), Positives = 85/175 (48%), Gaps = 1/175 (0%)
Frame = +1
Query: 241 VTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITE-XX 417
+++ A+ A+ + +E + ++ G++VA+ G + T+GLW+++ +V D PI E
Sbjct: 374 ISLNGAIRAAMRDILESNPMAWIYGQDVAERGGVMQATKGLWERF-PSQVRDAPINEPLI 432
Query: 418 XXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAA 597
+ E ++S+ + +++ + S GTV ++ R P
Sbjct: 433 LGTAVGYAMHEGATALPEIQFSDYSLNTLHWLVH-LGNLLWTSNGTVKANVIVRLPVEPL 491
Query: 598 SSVAAQHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVMLEDEIMY 762
+ HS C +Y+ PGL +L P ++ D GLL++A PVV+LE + +Y
Sbjct: 492 HGGSVYHSMCMEGFYAAIPGLTILAPTTSRDFYGLLRSAAEYDGPVVILESKGLY 546
>UniRef50_Q11G19 Cluster: Transketolase-like; n=2;
Proteobacteria|Rep: Transketolase-like - Mesorhizobium
sp. (strain BNC1)
Length = 323
Score = 73.3 bits (172), Expect = 6e-12
Identities = 49/165 (29%), Positives = 78/165 (47%), Gaps = 5/165 (3%)
Frame = +1
Query: 265 QAIDEEMERDEK---VFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXXXX 435
+A+ EM D +F L VA G ++ L K++G RV++T I E
Sbjct: 12 EAVQHEMLEDPNMVWIFELTPPVASNPG--RLVINLEKQFGRNRVVNTGIDENWMASATL 69
Query: 436 XXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVF-RGPNGAASSVAA 612
+ ++ + + I N A K +M+ G +P+VF G A
Sbjct: 70 GAGLAGSRA-ATYVPYQGACMPFQVIQNHAGKLRHMTGGKASMPVVFIMEMTGQTPGFAG 128
Query: 613 QHSQC-FGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVML 744
QHS +Y+H PG+K ++P + DAKG++ +A+RDP+PVV L
Sbjct: 129 QHSDYEIDTYYAHIPGVKTVIPSTPYDAKGMMVSALRDPNPVVYL 173
>UniRef50_UPI000038D520 Cluster: COG0022: Pyruvate/2-oxoglutarate
dehydrogenase complex, dehydrogenase (E1) component,
eukaryotic type, beta subunit; n=1; Nostoc punctiforme
PCC 73102|Rep: COG0022: Pyruvate/2-oxoglutarate
dehydrogenase complex, dehydrogenase (E1) component,
eukaryotic type, beta subunit - Nostoc punctiforme PCC
73102
Length = 343
Score = 72.1 bits (169), Expect = 1e-11
Identities = 48/173 (27%), Positives = 77/173 (44%), Gaps = 1/173 (0%)
Frame = +1
Query: 247 VRDALNQAIDEEMERDEKVFVLGEEVAQ-YDGAYKVTRGLWKKYGDKRVIDTPITEXXXX 423
V + LN+A+ D +VF++GE++ Y GA+KV +GL Y D RV+ TPI+E
Sbjct: 11 VVENLNRALHHIFAVDPQVFLIGEDILDPYGGAFKVGKGLSSNYPD-RVLTTPISEEAIV 69
Query: 424 XXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASS 603
KPI E M +F D I+N A+K+ M + + ++ R G
Sbjct: 70 GIGGGLALCGNKPIIEIMFGDFIALGFDQILNFASKSVSMYGTKLDLNMIVRCAVGGNRG 129
Query: 604 VAAQHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVMLEDEIMY 762
HSQ + P L + D + + + P + ED+++Y
Sbjct: 130 YGPTHSQSLQKHFVGIPNLYLFELSPLHDNIAVFEKLVNLTFPCIFFEDKVLY 182
>UniRef50_Q7N5R1 Cluster: Similar to 3-methyl-2-oxobutanoate
dehydrogenase; n=1; Photorhabdus luminescens subsp.
laumondii|Rep: Similar to 3-methyl-2-oxobutanoate
dehydrogenase - Photorhabdus luminescens subsp.
laumondii
Length = 665
Score = 71.3 bits (167), Expect = 2e-11
Identities = 44/171 (25%), Positives = 76/171 (44%), Gaps = 3/171 (1%)
Frame = +1
Query: 256 ALNQAIDEEMERDEKVFVLGEEVAQ-YDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXXX 432
A+NQ +DE + + V + GE++ G + TRGL +Y D RVI+ P++E
Sbjct: 348 AVNQVLDEALSQHPNVLIFGEDIEDPKGGVFGFTRGLSTRYPD-RVINAPLSEATIIGSS 406
Query: 433 XXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGA-ASSVA 609
+PI E +F ++ + + + + G P+V P GA
Sbjct: 407 VGLSASGWRPIVELQFIDFVGLGLNQLQSQLGTLSWRTVGKWRCPVVIYAPYGAYLPGGG 466
Query: 610 AQHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIR-DPDPVVMLEDEIM 759
HSQ +H PG+ VL+P + D L + A+ D ++++ +M
Sbjct: 467 IWHSQSSDGILAHIPGINVLVPTTPADTVALFRTALSLDMPSLILIPKHLM 517
>UniRef50_A7P4X0 Cluster: Chromosome chr4 scaffold_6, whole genome
shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
chr4 scaffold_6, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 111
Score = 71.3 bits (167), Expect = 2e-11
Identities = 38/76 (50%), Positives = 44/76 (57%)
Frame = +1
Query: 538 YMSAGTVPVPIVFRGPNGAASSVAAQHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAI 717
Y + PI G G V AQHSQC Y GLK L PYS+EDA GLLK +
Sbjct: 24 YNPEKVLDTPITEAGFTGIG--VGAQHSQCNITGYGSYSGLKALSPYSSEDAHGLLKVVM 81
Query: 718 RDPDPVVMLEDEIMYG 765
RD DPVV LE+E++YG
Sbjct: 82 RDLDPVVFLENELLYG 97
>UniRef50_A4F1Y5 Cluster: Branched-chain alpha-keto acid
decarboxylase; n=1; Streptomyces virginiae|Rep:
Branched-chain alpha-keto acid decarboxylase -
Streptomyces virginiae
Length = 677
Score = 70.5 bits (165), Expect = 4e-11
Identities = 41/169 (24%), Positives = 79/169 (46%), Gaps = 2/169 (1%)
Frame = +1
Query: 244 TVRDALNQAIDEEMERDEKVFVLGEEVAQ-YDGAYKVTRGLWKKYGDKRVIDTPITEXXX 420
T+ +A+N+A+ +E D + + GE++ G + T+GL G R+ ++P+ E
Sbjct: 357 TMVEAVNRALRTGLENDPTLVLFGEDIEDPKGGVFGFTKGLGTLAGP-RMTNSPLAEATI 415
Query: 421 XXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGP-NGAA 597
++P+ E +F+ A + I + + +A P+V P G
Sbjct: 416 VGAAVGLAAAGMRPVVELQFVDFAGPAWNQIASQLTTLRWRTASAWRCPVVIYAPWGGYL 475
Query: 598 SSVAAQHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVML 744
HSQ + ++H PGL+V++P + ED + + + PDP ++L
Sbjct: 476 PGGGIWHSQSNESLFTHLPGLRVVVPSTPEDTEAVFLESFASPDPTLIL 524
>UniRef50_Q748I3 Cluster: Dehydrogenase, E1 component, alpha and
beta subunits; n=1; Geobacter sulfurreducens|Rep:
Dehydrogenase, E1 component, alpha and beta subunits -
Geobacter sulfurreducens
Length = 652
Score = 66.1 bits (154), Expect = 9e-10
Identities = 42/172 (24%), Positives = 79/172 (45%), Gaps = 3/172 (1%)
Frame = +1
Query: 256 ALNQAIDEEMERDEKVFVLGEEV-AQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXXX 432
++N ++ +E + K ++GE++ A Y GA+K T+ L + RV +TPI+E
Sbjct: 330 SINLSLQSLLENNSKAVIIGEDIEAPYGGAFKATKDLSTLFPG-RVKNTPISEGAITGVG 388
Query: 433 XXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASSVAA 612
P+ E M +F D ++ A K M + VP++ R P G
Sbjct: 389 IGLALSGFLPVVEIMFGDFMTLTFDQLLQHAGKFCEMYGKDLDVPLIIRTPMGGRRGYGP 448
Query: 613 QHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDP--DPVVMLEDEIMY 762
HSQ ++ P L+V+ Y+ + L+ + P +++E++++Y
Sbjct: 449 THSQSLEKFFLGIPNLEVI-AYNHRVSPALIFGNLCKTIRRPTLIIENKVLY 499
>UniRef50_Q8AB00 Cluster: 2-oxoisovalerate dehydrogenase beta
subunit; n=11; cellular organisms|Rep: 2-oxoisovalerate
dehydrogenase beta subunit - Bacteroides
thetaiotaomicron
Length = 678
Score = 63.7 bits (148), Expect = 5e-09
Identities = 42/175 (24%), Positives = 79/175 (45%), Gaps = 5/175 (2%)
Frame = +1
Query: 253 DALNQAIDEEMERDEKVFVLGEEVAQYD--GAYKVTRGLWKKYGDKRVIDTPITEXXXXX 426
+A+N+ + E + F+ G++VA + G + VT+G+ +++G+ RV PI E
Sbjct: 354 NAINETLKAEFRHNPDTFIWGQDVANREKGGVFNVTKGMQQEFGEARVFSAPIAEDYIVG 413
Query: 427 XXXXXXXXXLK--PICEFMTF-NFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAA 597
K + E F ++ A++ + + ++ S G I R +G
Sbjct: 414 TANGMSRFDPKIHVVIEGAEFADYFWPAVEQYVECTHE-YWRSNGKFAPNITLRLASGGY 472
Query: 598 SSVAAQHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVMLEDEIMY 762
HSQ + PG +++ P A+DA GLL+ ++R + LE + +Y
Sbjct: 473 IGGGLYHSQNIEGALTTLPGARIVCPSFADDAAGLLRTSMRSKGFTLFLEPKALY 527
>UniRef50_A3PXW7 Cluster: Transketolase domain protein; n=4;
Mycobacterium|Rep: Transketolase domain protein -
Mycobacterium sp. (strain JLS)
Length = 721
Score = 63.7 bits (148), Expect = 5e-09
Identities = 46/161 (28%), Positives = 67/161 (41%), Gaps = 2/161 (1%)
Frame = +1
Query: 241 VTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXX 420
VTV A+N+A+ + + + V GE+VA+ G Y VTRGL +K G RV DT + E
Sbjct: 386 VTVAQAVNRALADALAHHPEALVFGEDVARKGGVYGVTRGLQQKAGPARVFDTLLDEQAI 445
Query: 421 XXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFR-GPNGAA 597
L PI E + A D I AA + + P+V R G
Sbjct: 446 LGLALGAGVSGLLPIPEIQYLAYFHNAADQIRGEAATLQFFADRQYRNPMVVRVAGYGYQ 505
Query: 598 SSVAAQ-HSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAI 717
H+ A PG+ + P +DA ++ A +
Sbjct: 506 KGFGGHFHNDNSIAAMRDIPGVVIASPARPDDAAAMMHACV 546
>UniRef50_Q50851 Cluster: Branched-chain keto acid dehydrogenase E1
beta subunit; n=5; Deltaproteobacteria|Rep:
Branched-chain keto acid dehydrogenase E1 beta subunit -
Myxococcus xanthus
Length = 352
Score = 63.3 bits (147), Expect = 7e-09
Identities = 43/152 (28%), Positives = 71/152 (46%), Gaps = 1/152 (0%)
Frame = +1
Query: 307 VLGEEV-AQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXXXXXXXXXXLKPICEFMTF 483
+ GE+V A G + T+GL K ++P+ E +P+ E
Sbjct: 24 IFGEDVGAPLGGVFTCTQGL------KTTWNSPLDERGIIGAAMGIAMAGGRPVAEIQFC 77
Query: 484 NFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASSVAAQHSQCFGAWYSHCPGLK 663
++ ID ++ A T + + G +P+V R P G+ + HS F A +H G K
Sbjct: 78 DYVYNTID-LLKLAGNTSWSTFGDWNLPMVVRTPVGSGIRGSIYHSHSFDATMTHIAGWK 136
Query: 664 VLMPYSAEDAKGLLKAAIRDPDPVVMLEDEIM 759
V+MP + DA GLL A ++ +PV+ LE + +
Sbjct: 137 VVMPSTPLDAYGLLITACQEKNPVMFLEPKAL 168
>UniRef50_Q5AT21 Cluster: Putative uncharacterized protein; n=1;
Emericella nidulans|Rep: Putative uncharacterized
protein - Emericella nidulans (Aspergillus nidulans)
Length = 376
Score = 62.9 bits (146), Expect = 9e-09
Identities = 38/104 (36%), Positives = 54/104 (51%), Gaps = 1/104 (0%)
Frame = +1
Query: 454 LKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASSVAAQHSQCFG 633
+KP+ E ++ A D I+N AAK Y T G A A HSQ
Sbjct: 135 MKPVAEIQFADYVFPAFDQIVNEAAKFRYREGAT----------GGNAGHGALYHSQSPE 184
Query: 634 AWYSHCPGLKVLMPYSAEDAKGLLKAAI-RDPDPVVMLEDEIMY 762
A ++H PGL+V++P S AKGLL A+I +PVV +E +++Y
Sbjct: 185 ALFAHIPGLQVVIPRSPSQAKGLLLASIFESKNPVVFMEPKVLY 228
>UniRef50_A1GCL6 Cluster: Transketolase-like; n=2; Salinispora|Rep:
Transketolase-like - Salinispora arenicola CNS205
Length = 805
Score = 62.5 bits (145), Expect = 1e-08
Identities = 42/162 (25%), Positives = 69/162 (42%), Gaps = 2/162 (1%)
Frame = +1
Query: 238 PVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXX 417
P+T+ ++N A+ + + ++ V GE+V G Y VT+GL +++G RV DT + E
Sbjct: 464 PLTLAQSINAALADGLLEHPRMAVFGEDVGAKGGVYGVTKGLRERFGAARVFDTLLDETS 523
Query: 418 XXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFR--GPNG 591
+ P+ E + A D + AA + S G P+V R G
Sbjct: 524 ILGLGLGAGLAGMLPVPEIQYLGYLHNAEDQLRGEAATMQFFSQGAYRNPMVVRIAGLAY 583
Query: 592 AASSVAAQHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAI 717
H+ A PGL V +P +DA +L+ +
Sbjct: 584 QQGFGGHFHNDNSVAVLRDVPGLVVAVPARPDDAASMLRTCL 625
>UniRef50_A4BZ87 Cluster: Acetoin dehydrogenase (TPP-dependent) beta
chain; n=20; cellular organisms|Rep: Acetoin
dehydrogenase (TPP-dependent) beta chain - Polaribacter
irgensii 23-P
Length = 817
Score = 60.9 bits (141), Expect = 3e-08
Identities = 39/169 (23%), Positives = 68/169 (40%)
Frame = +1
Query: 241 VTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXX 420
V R + D +++ +V + GE+ + GL +KYGD RV DT I E
Sbjct: 483 VDARVVMRDNFDALLKKHPEVIIFGEDAGFIGDVNQGLEGLQEKYGDIRVSDTGIREATI 542
Query: 421 XXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAAS 600
L+PI E ++ + A+ + + A Y S G P++ R
Sbjct: 543 IGQGIGLAMRGLRPIAEIQYLDYLLYALQIMSDDLATLHYRSFGKQKAPLIIRTRGHRLE 602
Query: 601 SVAAQHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVMLE 747
+ S G ++ G+ VL+P + A G + +P +++E
Sbjct: 603 GIWHAGSP-MGGIINNIRGMHVLVPRNMNKAAGFYNTLLEGDEPALVIE 650
>UniRef50_Q7V0M6 Cluster: Dehydrogenase E1 component beta subunit;
n=1; Prochlorococcus marinus subsp. pastoris str.
CCMP1986|Rep: Dehydrogenase E1 component beta subunit -
Prochlorococcus marinus subsp. pastoris (strain CCMP
1378 / MED4)
Length = 309
Score = 57.6 bits (133), Expect = 3e-07
Identities = 39/148 (26%), Positives = 63/148 (42%)
Frame = +1
Query: 253 DALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXXX 432
+ + + +E E ++ LGE+V + GL +KYGDK++ID PI+E
Sbjct: 5 EKFREELFKEFESNKDAIYLGEDVRNAHRGIAI--GLHEKYGDKQIIDMPISESAFTGLA 62
Query: 433 XXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASSVAA 612
K E+ +D I N A K M + + +++ P G +A
Sbjct: 63 LGLAISKKKVFVEYNFAGLVYLGLDQIFNQAHKYNEMLNTNLNLDLIYILPTGTRGGLAG 122
Query: 613 QHSQCFGAWYSHCPGLKVLMPYSAEDAK 696
HS A SH G++ MP +A D +
Sbjct: 123 HHSDNPYAILSHL-GIQSFMPTNAIDCE 149
>UniRef50_Q7NLM8 Cluster: Gll1094 protein; n=1; Gloeobacter
violaceus|Rep: Gll1094 protein - Gloeobacter violaceus
Length = 481
Score = 56.4 bits (130), Expect = 7e-07
Identities = 33/142 (23%), Positives = 63/142 (44%), Gaps = 2/142 (1%)
Frame = +1
Query: 235 KPVTVRDALNQAIDEEMERDEKVFVLGEEVAQ-YDGAYKVTRGLWKKYGDKRVIDTPITE 411
+ T+ A+NQ + E ++ ++ + G+++ G + T+GL ++ +RV ++P+ E
Sbjct: 333 RTTTMVAAINQTLREALQLYPQMIMFGQDIEDPKGGVFGFTKGLSSQFS-QRVTNSPLAE 391
Query: 412 XXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNG 591
KP+ E +F A + ++ A + S G P+V P G
Sbjct: 392 ATIVGVAAGLAATGYKPVFELQFIDFITPAFNQLVQQIATLRWRSQGDWSCPMVLYAPYG 451
Query: 592 A-ASSVAAQHSQCFGAWYSHCP 654
A + HSQ W++H P
Sbjct: 452 AYLPGGSTWHSQSNEGWWTHIP 473
>UniRef50_Q5LVW0 Cluster: Dehydrogenase/transketolase family
protein; n=23; Proteobacteria|Rep:
Dehydrogenase/transketolase family protein -
Silicibacter pomeroyi
Length = 740
Score = 56.4 bits (130), Expect = 7e-07
Identities = 48/192 (25%), Positives = 77/192 (40%), Gaps = 6/192 (3%)
Frame = +1
Query: 205 SFATSKALASKPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDK 384
+F +P + +N A+ + M ++ +GE+V + G Y VT+ L +++G
Sbjct: 392 TFGGDMRAMDEPQPMSRLINWALTDLMLEHGEIVCMGEDVGRKGGVYGVTQKLQQRFGPD 451
Query: 385 RVIDTPITEXXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPV 564
R+IDT + E PI E + A D I AA + S G
Sbjct: 452 RMIDTLLDEQSILGLAIGMGHNGFLPIPEIQFLAYLHNAEDQIRGEAATLPFFSNGQFTN 511
Query: 565 PIVFR--GPNGAASSVAAQHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIR----DP 726
P+V R G H+ A PG+ + P + EDA +L+ +R +
Sbjct: 512 PMVLRIAGLGYQKGFGGHFHNDNSLAVLRDIPGVIIACPSTGEDAAQMLRECVRLAREEQ 571
Query: 727 DPVVMLEDEIMY 762
VV LE +Y
Sbjct: 572 RVVVFLEPIALY 583
>UniRef50_A2C5U9 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
complex, dehydrogenase (E1) component, eukaryotic type,
beta subunit; n=1; Prochlorococcus marinus str. MIT
9303|Rep: Pyruvate/2-oxoglutarate dehydrogenase complex,
dehydrogenase (E1) component, eukaryotic type, beta
subunit - Prochlorococcus marinus (strain MIT 9303)
Length = 359
Score = 55.2 bits (127), Expect = 2e-06
Identities = 34/138 (24%), Positives = 56/138 (40%)
Frame = +1
Query: 334 DGAYKVTRGLWKKYGDKRVIDTPITEXXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHI 513
DG Y L + + + P +E + I F F++ A++
Sbjct: 40 DGFYGTIAELSTHFSSQ-CYELPCSENASVGLAISASAYEVTTILCFQRVEFALLALEQF 98
Query: 514 INSAAKTFYMSAGTVPVPIVFRGPNGAASSVAAQHSQCFGAWYSHCPGLKVLMPYSAEDA 693
IN+AAK +++ G P P +FR G HSQ ++ P + VLMP D+
Sbjct: 99 INNAAKNNFLAGGRRPNPCLFRFVIGRGWGQGPSHSQSLETIFAQIPNINVLMPVFPRDS 158
Query: 694 KGLLKAAIRDPDPVVMLE 747
+ + K + P + LE
Sbjct: 159 EFIFKNFVNLTAPTISLE 176
>UniRef50_UPI0000D9ADA1 Cluster: PREDICTED: similar to
2-oxoisovalerate dehydrogenase beta subunit,
mitochondrial precursor (Branched-chain alpha-keto acid
dehydrogenase E1 component beta chain) (BCKDH E1-beta);
n=1; Macaca mulatta|Rep: PREDICTED: similar to
2-oxoisovalerate dehydrogenase beta subunit,
mitochondrial precursor (Branched-chain alpha-keto acid
dehydrogenase E1 component beta chain) (BCKDH E1-beta) -
Macaca mulatta
Length = 340
Score = 46.0 bits (104), Expect = 0.001
Identities = 23/87 (26%), Positives = 39/87 (44%)
Frame = +1
Query: 256 ALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXXXX 435
++ A+D + +D + GE+VA + G ++ T GL KYG RV +TP+ E
Sbjct: 76 SVTSALDNSLAKDPTAVIFGEDVA-FGGVFRCTVGLRDKYGKDRVFNTPLCEQGIVGFGI 134
Query: 436 XXXXXXLKPICEFMTFNFSMQAIDHII 516
I E ++ A D ++
Sbjct: 135 GIAVTGATAIAEIQFADYIFPAFDQVV 161
>UniRef50_UPI0000383A75 Cluster: COG0508: Pyruvate/2-oxoglutarate
dehydrogenase complex, dihydrolipoamide acyltransferase
(E2) component, and related enzymes; n=1;
Magnetospirillum magnetotacticum MS-1|Rep: COG0508:
Pyruvate/2-oxoglutarate dehydrogenase complex,
dihydrolipoamide acyltransferase (E2) component, and
related enzymes - Magnetospirillum magnetotacticum MS-1
Length = 188
Score = 38.3 bits (85), Expect = 0.21
Identities = 22/55 (40%), Positives = 28/55 (50%), Gaps = 1/55 (1%)
Frame = +1
Query: 220 KALAS-KPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGD 381
K AS K T+R+AL A+D EM D V + G Y GA + GLW+ D
Sbjct: 116 KVYASYKRQTIREALRDAMDREMRADPDVLLNGRGTGPYHGANRAA-GLWRNGAD 169
>UniRef50_UPI00015970BB Cluster: GabT1; n=1; Bacillus
amyloliquefaciens FZB42|Rep: GabT1 - Bacillus
amyloliquefaciens FZB42
Length = 425
Score = 35.9 bits (79), Expect = 1.1
Identities = 20/59 (33%), Positives = 33/59 (55%), Gaps = 1/59 (1%)
Frame = +1
Query: 226 LASKPVTVRDALNQAIDEE-MERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDT 399
+ +K +T D+L ++D+ MER E +++ +E +Y T L YG+K VIDT
Sbjct: 4 VGTKEITNPDSLYYSVDDVVMERGEGIYLYDQEGNEYIDCASATFNLNLGYGNKEVIDT 62
>UniRef50_A6GB58 Cluster: Transketolase; n=1; Plesiocystis pacifica
SIR-1|Rep: Transketolase - Plesiocystis pacifica SIR-1
Length = 336
Score = 35.9 bits (79), Expect = 1.1
Identities = 32/160 (20%), Positives = 69/160 (43%), Gaps = 2/160 (1%)
Frame = +1
Query: 259 LNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDK-RVIDTPITEXXXXXXXX 435
L + + E + DE+ +LGE+V G ++R + + + R++ P+T
Sbjct: 7 LARLLVELLREDERRCLLGEDVGN-GGMLGLSRAVAEDEQLRARLMPAPLTVNAGVAHAG 65
Query: 436 XXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASSVAAQ 615
L+PI + + ++A+ + + + S +P++F PNG + +
Sbjct: 66 GLALAGLRPIVVLPSASALLEALP-ALRELGRLPWRSGEQHDLPVLFVVPNGPGFGIGGE 124
Query: 616 HSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIR-DPDP 732
++ A + PGL++ E+ L++A D +P
Sbjct: 125 AAESVEATLARVPGLELWAAGRIEELCACLRSAAEFDAEP 164
>UniRef50_Q2IY37 Cluster: Tyrosinase; n=1; Rhodopseudomonas
palustris HaA2|Rep: Tyrosinase - Rhodopseudomonas
palustris (strain HaA2)
Length = 416
Score = 34.3 bits (75), Expect = 3.4
Identities = 19/51 (37%), Positives = 27/51 (52%)
Frame = +1
Query: 211 ATSKALASKPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGL 363
A+ LASKPV VR N + ERD+ + LG A+ G Y++ R +
Sbjct: 102 ASGAPLASKPVMVRIRKNAVTLSQEERDDFLAALGTLNARGQGPYRIVRDM 152
>UniRef50_A6LE04 Cluster: Putative uncharacterized protein; n=2;
Parabacteroides|Rep: Putative uncharacterized protein -
Parabacteroides distasonis (strain ATCC 8503 / DSM 20701
/ NCTC11152)
Length = 334
Score = 34.3 bits (75), Expect = 3.4
Identities = 20/64 (31%), Positives = 30/64 (46%), Gaps = 1/64 (1%)
Frame = +1
Query: 196 SRRSFATSKALASKPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYK-VTRGLWKK 372
++ +F +A + VR + + + EK F L E Y G Y+ V RGLW+
Sbjct: 221 AQEAFTEDYLVAMRDSVVRRNVPGSFPNSYMKTEKRFELSYEPITYRGEYRGVLRGLWRM 280
Query: 373 YGDK 384
GDK
Sbjct: 281 EGDK 284
>UniRef50_Q8EVJ3 Cluster: Transposase for IS1202-like insertion
sequence element; n=7; Mycoplasma penetrans|Rep:
Transposase for IS1202-like insertion sequence element -
Mycoplasma penetrans
Length = 562
Score = 33.9 bits (74), Expect = 4.6
Identities = 17/40 (42%), Positives = 24/40 (60%)
Frame = +1
Query: 184 LTRLSRRSFATSKALASKPVTVRDALNQAIDEEMERDEKV 303
L ++ R+S ATSKA+ K R AL + D ER+EK+
Sbjct: 512 LEKIKRKSIATSKAIYQKNENTRIALERWSDSLKEREEKI 551
>UniRef50_Q2IQQ3 Cluster: Putative uncharacterized protein
precursor; n=1; Anaeromyxobacter dehalogenans 2CP-C|Rep:
Putative uncharacterized protein precursor -
Anaeromyxobacter dehalogenans (strain 2CP-C)
Length = 226
Score = 33.9 bits (74), Expect = 4.6
Identities = 23/75 (30%), Positives = 36/75 (48%)
Frame = -1
Query: 635 APKHWECCAATLEAAPLGPRNTIGTGTVPADI*KVLAAEFII*SIACIEKLKVMNSQIGL 456
AP+H E LE LGPR + V ++ + A+E +A + L + +
Sbjct: 110 APRHVE----VLETTSLGPRRALVLARVGDEVLLLGASEA---GLALLRALPAVPAPAAA 162
Query: 455 SPAKAAPTAIPANPA 411
+PA+A P +PA PA
Sbjct: 163 APAQAVPPPLPARPA 177
>UniRef50_A1AY54 Cluster: Regulatory protein, LuxR; n=1; Paracoccus
denitrificans PD1222|Rep: Regulatory protein, LuxR -
Paracoccus denitrificans (strain Pd 1222)
Length = 589
Score = 33.9 bits (74), Expect = 4.6
Identities = 20/82 (24%), Positives = 37/82 (45%)
Frame = +1
Query: 469 EFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASSVAAQHSQCFGAWYSH 648
+ +TF +++ +D + + + ++ VP P PNG + + + FG
Sbjct: 79 QLLTFRNTLEKLD--VPTESDPLKLAVSEVPGPATVLSPNGNVAVINIAGERAFGTRQGA 136
Query: 649 CPGLKVLMPYSAEDAKGLLKAA 714
+ V+ P S ED LL+AA
Sbjct: 137 FMDVAVIAPNSLEDYCALLRAA 158
>UniRef50_Q4SZE5 Cluster: Chromosome undetermined SCAF11680, whole
genome shotgun sequence; n=1; Tetraodon
nigroviridis|Rep: Chromosome undetermined SCAF11680,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 462
Score = 33.5 bits (73), Expect = 6.0
Identities = 13/26 (50%), Positives = 14/26 (53%)
Frame = -1
Query: 635 APKHWECCAATLEAAPLGPRNTIGTG 558
AP HWE PLGPR +GTG
Sbjct: 287 APVHWEFSLEPAAGGPLGPRGPVGTG 312
>UniRef50_Q4SI33 Cluster: Chromosome 5 SCAF14581, whole genome shotgun
sequence; n=9; Clupeocephala|Rep: Chromosome 5 SCAF14581,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 943
Score = 33.1 bits (72), Expect = 8.0
Identities = 17/41 (41%), Positives = 22/41 (53%), Gaps = 3/41 (7%)
Frame = +2
Query: 8 RPPFIL---RRGSFAHLISFXPKLSSYLANKPPCWFRCCKN 121
RP +L R S LI +L++ L+ PPC FRCC N
Sbjct: 902 RPGLLLSEQRTSSGTLLIQHTSRLTAPLSTNPPCEFRCCGN 942
>UniRef50_Q89XT5 Cluster: Glyoxalase II; n=16;
Alphaproteobacteria|Rep: Glyoxalase II - Bradyrhizobium
japonicum
Length = 255
Score = 33.1 bits (72), Expect = 8.0
Identities = 15/29 (51%), Positives = 21/29 (72%)
Frame = -1
Query: 236 LEARAFDVAKLRRDNRVSIPRTAGDDFNA 150
L+ARA +VAKLR +N+ +IP GD+ A
Sbjct: 191 LQARAAEVAKLRAENKPTIPSLLGDEKRA 219
>UniRef50_Q47C78 Cluster: Isochorismate synthase; n=1; Dechloromonas
aromatica RCB|Rep: Isochorismate synthase -
Dechloromonas aromatica (strain RCB)
Length = 444
Score = 33.1 bits (72), Expect = 8.0
Identities = 21/70 (30%), Positives = 31/70 (44%)
Frame = +1
Query: 514 INSAAKTFYMSAGTVPVPIVFRGPNGAASSVAAQHSQCFGAWYSHCPGLKVLMPYSAEDA 693
+N+ F + P P V P+ AA S A H + WYS GL +L P +
Sbjct: 329 VNTETSLFDLVRTLHPTPAVGGFPSAAAQSWLAAHGEARSGWYS--GGLGILTPDGDGEF 386
Query: 694 KGLLKAAIRD 723
L++A+ D
Sbjct: 387 SVALRSALID 396
>UniRef50_Q2I773 Cluster: PlaT6; n=9; Actinomycetales|Rep: PlaT6 -
Streptomyces sp. Tu6071
Length = 593
Score = 33.1 bits (72), Expect = 8.0
Identities = 38/145 (26%), Positives = 53/145 (36%), Gaps = 4/145 (2%)
Frame = +1
Query: 319 EVAQYDGAYKVTRGLWK---KYGDKRVIDTPITEXXXXXXXXXXXXXXLKPICEFMTFNF 489
EV A V GL K K+ D RV D I+E L+P+ + F
Sbjct: 299 EVVGITAAMTVPVGLHKFAAKFPD-RVHDVGISEQHAVASAAGLATAGLRPVVAIYS-TF 356
Query: 490 SMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASSVAAQHSQCFGAWYSHCPGLKVL 669
+A D ++ A +PV V + H +W S PGL+V
Sbjct: 357 LARAFDQVLMDVA------LHRLPVVFVLDRAGVTGPDGPSHHGIWDLSWLSLVPGLRVA 410
Query: 670 MPYSAEDAKGLLKAAI-RDPDPVVM 741
P LL+ A+ RD P V+
Sbjct: 411 APRDTAQLGLLLREALDRDAGPTVL 435
>UniRef50_A7SMP5 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 414
Score = 33.1 bits (72), Expect = 8.0
Identities = 14/33 (42%), Positives = 20/33 (60%)
Frame = +3
Query: 180 DAHSIIPSQFCHIESSGF*AGDCKRCFKSSDRR 278
D S+ CH++S GF G C +CF +SDR+
Sbjct: 40 DPSSLALHVACHVKSKGFLCGQCNKCF-TSDRQ 71
>UniRef50_A7AWY3 Cluster: Putative uncharacterized protein; n=1;
Babesia bovis|Rep: Putative uncharacterized protein -
Babesia bovis
Length = 1099
Score = 33.1 bits (72), Expect = 8.0
Identities = 19/85 (22%), Positives = 41/85 (48%), Gaps = 3/85 (3%)
Frame = +1
Query: 130 SDIIFKMALKSSPAVLGMLTRLSRRSFATSKALASKPVTVRDALN---QAIDEEMERDEK 300
+D + ++ P V GM L+ F ++ + P++V D ++ A+ ++ + K
Sbjct: 582 ADFSDPLRIRWIPKVSGMRPILNCNYFKVNRGSVTGPISVNDMMHIPFHALRAHVQTNPK 641
Query: 301 VFVLGEEVAQYDGAYKVTRGLWKKY 375
+ LG + Y GAY + W+++
Sbjct: 642 I--LGNSILGYSGAYISVKRWWRRF 664
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 777,483,572
Number of Sequences: 1657284
Number of extensions: 15903896
Number of successful extensions: 43175
Number of sequences better than 10.0: 117
Number of HSP's better than 10.0 without gapping: 41474
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 43119
length of database: 575,637,011
effective HSP length: 99
effective length of database: 411,565,895
effective search space used: 65438977305
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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