Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P16_F_I12
(719 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AY390425-1|AAQ92353.1| 503|Homo sapiens cytochrome P450 CYP3A43... 81 4e-15
AY390424-1|AAQ92352.1| 503|Homo sapiens cytochrome P450 CYP3A43... 81 4e-15
AF337813-1|AAK38841.1| 503|Homo sapiens cytochrome P450 subfami... 81 4e-15
AF319634-1|AAK00325.1| 503|Homo sapiens cytochrome P450 CYP3A43... 81 4e-15
AF280111-1|AAG33012.1| 250|Homo sapiens cytochrome P450 subfami... 81 4e-15
AF280110-1|AAG33011.1| 420|Homo sapiens cytochrome P450 subfami... 81 4e-15
AF280109-1|AAG33010.1| 504|Homo sapiens cytochrome P450 subfami... 81 4e-15
AF280108-1|AAG33009.1| 503|Homo sapiens cytochrome P450 subfami... 81 4e-15
AC011904-5|AAS07394.1| 504|Homo sapiens unknown protein. 81 4e-15
AC011904-4|AAS07395.1| 503|Homo sapiens unknown protein. 81 4e-15
M13785-1|AAA35742.1| 504|Homo sapiens protein ( Human liver glu... 74 6e-13
D00003-1|BAA00001.1| 504|Homo sapiens cytochrome P-450 protein. 74 6e-13
J04813-1|AAA02993.1| 502|Homo sapiens cytochrome P450 PCN3 prot... 73 8e-13
DQ680079-1|ABG25922.1| 347|Homo sapiens truncated cytochrome P4... 73 8e-13
BC033862-1|AAH33862.1| 502|Homo sapiens cytochrome P450, family... 73 8e-13
AC005020-1|AAS02016.1| 502|Homo sapiens unknown protein. 73 8e-13
X12387-1|CAA30944.1| 503|Homo sapiens protein ( Human mRNA for ... 73 1e-12
M18907-1|AAA35745.1| 503|Homo sapiens protein ( Human P450 mRNA... 73 1e-12
M14096-1|AAA35744.1| 503|Homo sapiens protein ( Human cytochrom... 73 1e-12
DQ924960-1|ABI96208.1| 503|Homo sapiens cytochrome P450 family ... 73 1e-12
DQ005611-1|AAY16980.1| 503|Homo sapiens cytochrome P450, family... 73 1e-12
BC101631-1|AAI01632.1| 503|Homo sapiens cytochrome P450, subfam... 73 1e-12
BC069418-1|AAH69418.1| 503|Homo sapiens cytochrome P450, family... 73 1e-12
AK223008-1|BAD96728.1| 502|Homo sapiens cytochrome P450, family... 73 1e-12
AJ563375-1|CAD91343.1| 503|Homo sapiens cytochrome P450 protein. 73 1e-12
AF280107-2|AAG32290.1| 503|Homo sapiens cytochrome P450 polypep... 73 1e-12
AF209389-1|AAF21034.1| 503|Homo sapiens cytochrome P450 IIIA4 p... 73 1e-12
AF182273-1|AAF13598.1| 503|Homo sapiens cytochrome P450-3A4 pro... 73 1e-12
J04449-1|AAA35747.1| 502|Homo sapiens cytochrome P450 nifedipin... 72 2e-12
D00408-1|BAA00310.1| 503|Homo sapiens cytochrome P-450 HFLa pro... 70 1e-11
BC067436-1|AAH67436.1| 503|Homo sapiens cytochrome P450, family... 70 1e-11
AF315325-1|AAG48618.1| 535|Homo sapiens cytochrome P450 variant... 70 1e-11
AF280107-3|AAG32289.1| 503|Homo sapiens cytochrome P450 polypep... 70 1e-11
AC004914-1|AAD21788.1| 348|Homo sapiens unknown protein. 69 2e-11
D34625-1|BAA07011.1| 533|Homo sapiens thromboxane synthase prot... 69 2e-11
BC041157-1|AAH41157.1| 534|Homo sapiens thromboxane A synthase ... 69 2e-11
AK223466-1|BAD97186.1| 534|Homo sapiens thromboxane A synthase ... 69 2e-11
AF233619-1|AAF99273.1| 534|Homo sapiens thromboxane synthase pr... 67 7e-11
M80647-1|AAA60618.1| 534|Homo sapiens thromboxane synthase prot... 66 9e-11
M80646-1|AAA60617.1| 460|Homo sapiens thromboxane synthase prot... 66 9e-11
M74055-1|AAA36742.1| 229|Homo sapiens thromboxane synthase prot... 66 9e-11
AF233625-1|AAF99279.1| 534|Homo sapiens thromboxane synthase pr... 66 9e-11
AF233624-1|AAF99278.1| 534|Homo sapiens thromboxane synthase pr... 66 9e-11
AF233623-1|AAF99277.1| 534|Homo sapiens thromboxane synthase pr... 66 9e-11
AF233622-1|AAF99276.1| 534|Homo sapiens thromboxane synthase pr... 66 9e-11
AF233621-1|AAF99275.1| 534|Homo sapiens thromboxane synthase pr... 66 9e-11
AF233620-1|AAF99274.1| 534|Homo sapiens thromboxane synthase pr... 66 9e-11
AF233617-1|AAF99271.1| 534|Homo sapiens thromboxane synthase pr... 66 9e-11
AF233616-1|AAF99270.1| 534|Homo sapiens thromboxane synthase pr... 66 9e-11
AF233615-1|AAF99269.1| 534|Homo sapiens thromboxane synthase pr... 66 9e-11
L36085-1|AAC01761.1| 441|Homo sapiens thromboxane A2 synthase p... 66 1e-10
AF233618-1|AAF99272.1| 534|Homo sapiens thromboxane synthase pr... 66 1e-10
AJ563376-2|CAD91645.1| 430|Homo sapiens cytochrome P450 protein. 62 1e-09
AC004914-2|AAP21887.1| 311|Homo sapiens unknown protein. 61 3e-09
BC014117-1|AAH14117.1| 466|Homo sapiens TBXAS1 protein protein. 61 4e-09
Y00498-1|CAA68550.1| 490|Homo sapiens IIC2 protein. 40 0.007
M21941-1|AAA52160.1| 480|Homo sapiens CYP2C protein. 40 0.007
M17398-1|AAA35740.1| 393|Homo sapiens protein ( Human cytochrom... 40 0.007
M17397-1|AAA35739.1| 490|Homo sapiens protein ( Human cytochrom... 40 0.007
AY514490-1|AAR89907.1| 490|Homo sapiens cytochrome P450, family... 40 0.007
AL359672-5|CAH71307.1| 490|Homo sapiens cytochrome P450, family... 40 0.007
BC020596-1|AAH20596.1| 490|Homo sapiens cytochrome P450, family... 40 0.009
AF280107-1|AAG32291.1| 106|Homo sapiens cytochrome P450 polypep... 39 0.016
M21942-1|AAA52161.1| 462|Homo sapiens CYP2C protein. 39 0.021
M61856-1|AAB59356.1| 490|Homo sapiens cytochrome protein. 37 0.063
L16876-1|AAA02630.1| 490|Homo sapiens cytochrome P-4502C18 prot... 37 0.063
BC096260-1|AAH96260.1| 431|Homo sapiens CYP2C18 protein protein. 37 0.063
BC096259-1|AAH96259.1| 443|Homo sapiens CYP2C18 protein protein. 37 0.063
BC096258-1|AAH96258.1| 490|Homo sapiens cytochrome P450, family... 37 0.063
BC096257-1|AAH96257.1| 490|Homo sapiens cytochrome P450, family... 37 0.063
BC069666-1|AAH69666.1| 490|Homo sapiens cytochrome P450, family... 37 0.063
BC016853-1|AAH16853.1| 524|Homo sapiens CYP4F11 protein protein. 37 0.063
AL583836-1|CAH74067.1| 490|Homo sapiens cytochrome P450, family... 37 0.063
AF280107-4|AAG32288.1| 106|Homo sapiens cytochrome P450 polypep... 37 0.063
AF236085-1|AAG15889.1| 524|Homo sapiens CYP4F11 protein. 37 0.063
EF122242-1|ABO41977.1| 321|Homo sapiens cytochrome P450 2F1 var... 37 0.084
X13930-1|CAA32118.1| 494|Homo sapiens protein ( Human CYP2A4 mR... 36 0.11
M61854-1|AAB59426.1| 490|Homo sapiens cytochrome protein. 36 0.11
M33318-1|AAA52067.1| 494|Homo sapiens CYP2A protein. 36 0.11
L39098-1|AAL31347.1| 160|Homo sapiens S-mephenytoin 4-hydroxyla... 36 0.11
BC096256-1|AAH96256.1| 494|Homo sapiens cytochrome P450, family... 36 0.11
BC096255-1|AAH96255.1| 494|Homo sapiens cytochrome P450, family... 36 0.11
BC096254-1|AAH96254.1| 494|Homo sapiens cytochrome P450, family... 36 0.11
BC096253-1|AAH96253.3| 494|Homo sapiens cytochrome P450, family... 36 0.11
AY796203-1|AAV41877.1| 490|Homo sapiens cytochrome P450, family... 36 0.11
AL583836-2|CAH74068.1| 490|Homo sapiens cytochrome P450, family... 36 0.11
AL133513-2|CAH73444.1| 490|Homo sapiens cytochrome P450, family... 36 0.11
AF182275-1|AAF13600.1| 494|Homo sapiens cytochrome P450-2A6 pro... 36 0.11
X13897-1|CAA32097.1| 489|Homo sapiens protein ( Human mRNA for ... 36 0.15
M29873-1|AAA52143.1| 377|Homo sapiens CYP2B protein. 36 0.19
L07093-1|AAA36660.1| 468|Homo sapiens cytochrome P450 protein. 36 0.19
BC041174-1|AAH41174.1| 377|Homo sapiens CYP2B7P1 protein protein. 36 0.19
AK223510-1|BAD97230.1| 490|Homo sapiens cytochrome P450, family... 36 0.19
U22028-1|AAB40519.1| 494|Homo sapiens cytochrome P450 protein. 35 0.25
AY513609-1|AAR90940.1| 494|Homo sapiens cytochrome P450 2A13 va... 35 0.25
AY513608-1|AAR90939.1| 494|Homo sapiens cytochrome P450 2A13 va... 35 0.25
AY513606-1|AAR90937.1| 494|Homo sapiens cytochrome P450 2A13 va... 35 0.25
AY513605-1|AAR90936.1| 494|Homo sapiens cytochrome P450 2A13 va... 35 0.25
AY513604-1|AAR90935.1| 494|Homo sapiens cytochrome P450 2A13 va... 35 0.25
AF209774-1|AAG35775.1| 494|Homo sapiens cytochrome P450 2A13 pr... 35 0.25
S63426-1|ABB76283.1| 214|Homo sapiens (S)-mephenytoin hydroxyla... 35 0.34
M29874-1|AAA52144.1| 491|Homo sapiens CYP2B protein. 35 0.34
J02906-1|AAA52156.1| 491|Homo sapiens CYP2F1 protein. 35 0.34
DQ298753-1|ABB84469.1| 491|Homo sapiens cytochrome P450, family... 35 0.34
BC067431-1|AAH67431.1| 491|Homo sapiens cytochrome P450, family... 35 0.34
AF182277-1|AAF13602.1| 491|Homo sapiens cytochrome P450-2B6 pro... 35 0.34
AC023172-1|AAF32444.1| 491|Homo sapiens CYP2B6 protein. 35 0.34
BC067430-1|AAH67430.1| 491|Homo sapiens cytochrome P450, family... 34 0.45
U22027-1|AAB40518.1| 494|Homo sapiens cytochrome P450 protein. 34 0.59
S46963-1|AAB23864.2| 477|Homo sapiens cytochrome P-450 protein. 33 0.78
M21939-1|AAA52158.1| 485|Homo sapiens CYP2C protein. 33 0.78
M15331-1|AAA52157.1| 485|Homo sapiens CYP2C protein. 33 0.78
L16880-1|AAD13466.1| 273|Homo sapiens cytochrome P-450 2C protein. 33 0.78
EF122241-1|ABO41976.1| 491|Homo sapiens cytochrome P450 2F1 var... 33 0.78
D00173-1|BAA00123.1| 487|Homo sapiens cytochrome P-450 protein. 33 0.78
BC125054-1|AAI25055.1| 490|Homo sapiens cytochrome P450, family... 33 0.78
BC109056-1|AAI09057.1| 320|Homo sapiens CYP2F1 protein protein. 33 0.78
BC070317-1|AAH70317.1| 162|Homo sapiens CYP2C9 protein protein. 33 0.78
BC020754-1|AAH20754.1| 162|Homo sapiens CYP2C9 protein protein. 33 0.78
AY702706-1|AAT94065.1| 490|Homo sapiens cytochrome P450, family... 33 0.78
AY341248-1|AAP88931.1| 490|Homo sapiens cytochrome P450, family... 33 0.78
AL359672-1|CAH71303.1| 490|Homo sapiens cytochrome P450, family... 33 0.78
AF372573-1|AAL69652.1| 495|Homo sapiens cytochrome P450 2F1 pro... 33 0.78
BC033691-1|AAH33691.1| 504|Homo sapiens cytochrome P450, family... 33 1.0
BC028102-1|AAH28102.1| 509|Homo sapiens cytochrome P450, family... 33 1.0
AY358603-1|AAQ88966.1| 504|Homo sapiens Cytochrome p450 protein. 33 1.0
AY358537-1|AAQ88901.1| 509|Homo sapiens EFSW1929 protein. 33 1.0
AM040940-1|CAJ13826.1| 509|Homo sapiens cytochrome P450 protein. 33 1.0
AL450996-1|CAH71035.1| 509|Homo sapiens cytochrome P450, family... 33 1.0
AK098065-1|BAC05226.1| 509|Homo sapiens protein ( Homo sapiens ... 33 1.0
AK091806-1|BAC03751.1| 444|Homo sapiens protein ( Homo sapiens ... 33 1.0
AK027605-1|BAB55227.1| 564|Homo sapiens protein ( Homo sapiens ... 33 1.0
AF335278-1|AAK13498.1| 504|Homo sapiens cytochrome P450 2S1 pro... 33 1.0
BC035350-1|AAH35350.1| 524|Homo sapiens cytochrome P450, family... 32 2.4
AY358977-1|AAQ89336.1| 524|Homo sapiens CYP4F12 protein. 32 2.4
AY008841-1|AAG33247.1| 524|Homo sapiens cytochrome P450 isoform... 32 2.4
AC004523-1|AAC11543.1| 458|Homo sapiens F22329_1 protein. 32 2.4
AB035131-1|BAB18270.1| 524|Homo sapiens cytochrome P450 protein. 32 2.4
AB035130-1|BAB18269.1| 524|Homo sapiens cytochrome P450 protein. 32 2.4
BC060857-1|AAH60857.1| 525|Homo sapiens cytochrome P450, family... 31 3.1
AY422002-1|AAR31180.1| 525|Homo sapiens cytochrome P450 4V2 pro... 31 3.1
AK126473-1|BAC86562.1| 503|Homo sapiens protein ( Homo sapiens ... 31 3.1
AK122600-1|BAC85487.1| 525|Homo sapiens protein ( Homo sapiens ... 31 3.1
BC117165-1|AAI17166.1| 494|Homo sapiens cytochrome P450, family... 31 5.5
AY280372-1|AAQ21368.1| 519|Homo sapiens cytochrome P450 4A22 pr... 31 5.5
U19107-1|AAC13989.1| 507|Homo sapiens ZNF127 protein. 30 7.3
BC044639-1|AAH44639.1| 507|Homo sapiens makorin, ring finger pr... 30 7.3
U22029-1|AAB40520.1| 494|Homo sapiens cytochrome P450 protein. 30 9.6
AL135960-11|CAI19738.1| 455|Homo sapiens cytochrome P450, famil... 30 9.6
AL135960-10|CAI19736.1| 421|Homo sapiens cytochrome P450, famil... 30 9.6
AL135960-9|CAI19737.1| 519|Homo sapiens cytochrome P450, family... 30 9.6
AF208532-1|AAF76722.1| 519|Homo sapiens fatty acid omega-hydrox... 30 9.6
>AY390425-1|AAQ92353.1| 503|Homo sapiens cytochrome P450 CYP3A43.1
protein.
Length = 503
Score = 81.0 bits (191), Expect = 4e-15
Identities = 49/180 (27%), Positives = 88/180 (48%), Gaps = 1/180 (0%)
Frame = +2
Query: 2 WSTRKFDYWKRKNVPYAKPVPFFGNYMRYIT-LQSFLGDVMQKLCQQFPDRPYFGSFYGT 178
+ T +K+ +P P+PF G + Y+ L +F + +K + + G + G
Sbjct: 25 YGTHSHKLFKKLGIPGPTPLPFLGTILFYLRGLWNFDRECNEKYGEMW------GLYEGQ 78
Query: 179 EPALVLQNPEIIKQVFTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQNLTPLF 358
+P LV+ +P++IK V K+ Y + + L FA + WK IR L+P F
Sbjct: 79 QPMLVIMDPDMIKTVLVKECYSVFTNQ-MPLGPMGFLKSALSFAEDEEWKRIRTLLSPAF 137
Query: 359 SSSKMKNMFYLVEKCNHSLEDMLDKETKDLQSIEIRSAMIRYTLDSICSSAFGIETNTLS 538
+S K K M ++ +C L L +E ++ +SI ++ YT+D I + FG+ ++L+
Sbjct: 138 TSVKFKEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTMDVITGTLFGVNLDSLN 197
>AY390424-1|AAQ92352.1| 503|Homo sapiens cytochrome P450 CYP3A43.3
protein.
Length = 503
Score = 81.0 bits (191), Expect = 4e-15
Identities = 49/180 (27%), Positives = 88/180 (48%), Gaps = 1/180 (0%)
Frame = +2
Query: 2 WSTRKFDYWKRKNVPYAKPVPFFGNYMRYIT-LQSFLGDVMQKLCQQFPDRPYFGSFYGT 178
+ T +K+ +P P+PF G + Y+ L +F + +K + + G + G
Sbjct: 25 YGTHSHKLFKKLGIPGPTPLPFLGTILFYLRGLWNFDRECNEKYGEMW------GLYEGQ 78
Query: 179 EPALVLQNPEIIKQVFTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQNLTPLF 358
+P LV+ +P++IK V K+ Y + + L FA + WK IR L+P F
Sbjct: 79 QPMLVIMDPDMIKTVLVKECYSVFTNQ-MPLGPMGFLKSALSFAEDEEWKRIRTLLSPAF 137
Query: 359 SSSKMKNMFYLVEKCNHSLEDMLDKETKDLQSIEIRSAMIRYTLDSICSSAFGIETNTLS 538
+S K K M ++ +C L L +E ++ +SI ++ YT+D I + FG+ ++L+
Sbjct: 138 TSVKFKEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTMDVITGTLFGVNLDSLN 197
>AF337813-1|AAK38841.1| 503|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 503
Score = 81.0 bits (191), Expect = 4e-15
Identities = 49/180 (27%), Positives = 88/180 (48%), Gaps = 1/180 (0%)
Frame = +2
Query: 2 WSTRKFDYWKRKNVPYAKPVPFFGNYMRYIT-LQSFLGDVMQKLCQQFPDRPYFGSFYGT 178
+ T +K+ +P P+PF G + Y+ L +F + +K + + G + G
Sbjct: 25 YGTHSHKLFKKLGIPGPTPLPFLGTILFYLRGLWNFDRECNEKYGEMW------GLYEGQ 78
Query: 179 EPALVLQNPEIIKQVFTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQNLTPLF 358
+P LV+ +P++IK V K+ Y + + L FA + WK IR L+P F
Sbjct: 79 QPMLVIMDPDMIKTVLVKECYSVFTNQ-MPLGPMGFLKSALSFAEDEEWKRIRTLLSPAF 137
Query: 359 SSSKMKNMFYLVEKCNHSLEDMLDKETKDLQSIEIRSAMIRYTLDSICSSAFGIETNTLS 538
+S K K M ++ +C L L +E ++ +SI ++ YT+D I + FG+ ++L+
Sbjct: 138 TSVKFKEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTMDVITGTLFGVNLDSLN 197
>AF319634-1|AAK00325.1| 503|Homo sapiens cytochrome P450 CYP3A43
protein.
Length = 503
Score = 81.0 bits (191), Expect = 4e-15
Identities = 49/180 (27%), Positives = 88/180 (48%), Gaps = 1/180 (0%)
Frame = +2
Query: 2 WSTRKFDYWKRKNVPYAKPVPFFGNYMRYIT-LQSFLGDVMQKLCQQFPDRPYFGSFYGT 178
+ T +K+ +P P+PF G + Y+ L +F + +K + + G + G
Sbjct: 25 YGTHSHKLFKKLGIPGPTPLPFLGTILFYLRGLWNFDRECNEKYGEMW------GLYEGQ 78
Query: 179 EPALVLQNPEIIKQVFTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQNLTPLF 358
+P LV+ +P++IK V K+ Y + + L FA + WK IR L+P F
Sbjct: 79 QPMLVIMDPDMIKTVLVKECYSVFTNQ-MPLGPMGFLKSALSFAEDEEWKRIRTLLSPAF 137
Query: 359 SSSKMKNMFYLVEKCNHSLEDMLDKETKDLQSIEIRSAMIRYTLDSICSSAFGIETNTLS 538
+S K K M ++ +C L L +E ++ +SI ++ YT+D I + FG+ ++L+
Sbjct: 138 TSVKFKEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTMDVITGTLFGVNLDSLN 197
>AF280111-1|AAG33012.1| 250|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 250
Score = 81.0 bits (191), Expect = 4e-15
Identities = 49/180 (27%), Positives = 88/180 (48%), Gaps = 1/180 (0%)
Frame = +2
Query: 2 WSTRKFDYWKRKNVPYAKPVPFFGNYMRYIT-LQSFLGDVMQKLCQQFPDRPYFGSFYGT 178
+ T +K+ +P P+PF G + Y+ L +F + +K + + G + G
Sbjct: 25 YGTHSHKLFKKLGIPGPTPLPFLGTILFYLRGLWNFDRECNEKYGEMW------GLYEGQ 78
Query: 179 EPALVLQNPEIIKQVFTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQNLTPLF 358
+P LV+ +P++IK V K+ Y + + L FA + WK IR L+P F
Sbjct: 79 QPMLVIMDPDMIKTVLVKECYSVFTNQ-MPLGPMGFLKSALSFAEDEEWKRIRTLLSPAF 137
Query: 359 SSSKMKNMFYLVEKCNHSLEDMLDKETKDLQSIEIRSAMIRYTLDSICSSAFGIETNTLS 538
+S K K M ++ +C L L +E ++ +SI ++ YT+D I + FG+ ++L+
Sbjct: 138 TSVKFKEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTMDVITGTLFGVNLDSLN 197
>AF280110-1|AAG33011.1| 420|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 420
Score = 81.0 bits (191), Expect = 4e-15
Identities = 49/180 (27%), Positives = 88/180 (48%), Gaps = 1/180 (0%)
Frame = +2
Query: 2 WSTRKFDYWKRKNVPYAKPVPFFGNYMRYIT-LQSFLGDVMQKLCQQFPDRPYFGSFYGT 178
+ T +K+ +P P+PF G + Y+ L +F + +K + + G + G
Sbjct: 25 YGTHSHKLFKKLGIPGPTPLPFLGTILFYLRGLWNFDRECNEKYGEMW------GLYEGQ 78
Query: 179 EPALVLQNPEIIKQVFTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQNLTPLF 358
+P LV+ +P++IK V K+ Y + + L FA + WK IR L+P F
Sbjct: 79 QPMLVIMDPDMIKTVLVKECYSVFTNQ-MPLGPMGFLKSALSFAEDEEWKRIRTLLSPAF 137
Query: 359 SSSKMKNMFYLVEKCNHSLEDMLDKETKDLQSIEIRSAMIRYTLDSICSSAFGIETNTLS 538
+S K K M ++ +C L L +E ++ +SI ++ YT+D I + FG+ ++L+
Sbjct: 138 TSVKFKEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTMDVITGTLFGVNLDSLN 197
>AF280109-1|AAG33010.1| 504|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 504
Score = 81.0 bits (191), Expect = 4e-15
Identities = 49/180 (27%), Positives = 88/180 (48%), Gaps = 1/180 (0%)
Frame = +2
Query: 2 WSTRKFDYWKRKNVPYAKPVPFFGNYMRYIT-LQSFLGDVMQKLCQQFPDRPYFGSFYGT 178
+ T +K+ +P P+PF G + Y+ L +F + +K + + G + G
Sbjct: 25 YGTHSHKLFKKLGIPGPTPLPFLGTILFYLRGLWNFDRECNEKYGEMW------GLYEGQ 78
Query: 179 EPALVLQNPEIIKQVFTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQNLTPLF 358
+P LV+ +P++IK V K+ Y + + L FA + WK IR L+P F
Sbjct: 79 QPMLVIMDPDMIKTVLVKECYSVFTNQ-MPLGPMGFLKSALSFAEDEEWKRIRTLLSPAF 137
Query: 359 SSSKMKNMFYLVEKCNHSLEDMLDKETKDLQSIEIRSAMIRYTLDSICSSAFGIETNTLS 538
+S K K M ++ +C L L +E ++ +SI ++ YT+D I + FG+ ++L+
Sbjct: 138 TSVKFKEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTMDVITGTLFGVNLDSLN 197
>AF280108-1|AAG33009.1| 503|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 503
Score = 81.0 bits (191), Expect = 4e-15
Identities = 49/180 (27%), Positives = 88/180 (48%), Gaps = 1/180 (0%)
Frame = +2
Query: 2 WSTRKFDYWKRKNVPYAKPVPFFGNYMRYIT-LQSFLGDVMQKLCQQFPDRPYFGSFYGT 178
+ T +K+ +P P+PF G + Y+ L +F + +K + + G + G
Sbjct: 25 YGTHSHKLFKKLGIPGPTPLPFLGTILFYLRGLWNFDRECNEKYGEMW------GLYEGQ 78
Query: 179 EPALVLQNPEIIKQVFTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQNLTPLF 358
+P LV+ +P++IK V K+ Y + + L FA + WK IR L+P F
Sbjct: 79 QPMLVIMDPDMIKTVLVKECYSVFTNQ-MPLGPMGFLKSALSFAEDEEWKRIRTLLSPAF 137
Query: 359 SSSKMKNMFYLVEKCNHSLEDMLDKETKDLQSIEIRSAMIRYTLDSICSSAFGIETNTLS 538
+S K K M ++ +C L L +E ++ +SI ++ YT+D I + FG+ ++L+
Sbjct: 138 TSVKFKEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTMDVITGTLFGVNLDSLN 197
>AC011904-5|AAS07394.1| 504|Homo sapiens unknown protein.
Length = 504
Score = 81.0 bits (191), Expect = 4e-15
Identities = 49/180 (27%), Positives = 88/180 (48%), Gaps = 1/180 (0%)
Frame = +2
Query: 2 WSTRKFDYWKRKNVPYAKPVPFFGNYMRYIT-LQSFLGDVMQKLCQQFPDRPYFGSFYGT 178
+ T +K+ +P P+PF G + Y+ L +F + +K + + G + G
Sbjct: 25 YGTHSHKLFKKLGIPGPTPLPFLGTILFYLRGLWNFDRECNEKYGEMW------GLYEGQ 78
Query: 179 EPALVLQNPEIIKQVFTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQNLTPLF 358
+P LV+ +P++IK V K+ Y + + L FA + WK IR L+P F
Sbjct: 79 QPMLVIMDPDMIKTVLVKECYSVFTNQ-MPLGPMGFLKSALSFAEDEEWKRIRTLLSPAF 137
Query: 359 SSSKMKNMFYLVEKCNHSLEDMLDKETKDLQSIEIRSAMIRYTLDSICSSAFGIETNTLS 538
+S K K M ++ +C L L +E ++ +SI ++ YT+D I + FG+ ++L+
Sbjct: 138 TSVKFKEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTMDVITGTLFGVNLDSLN 197
>AC011904-4|AAS07395.1| 503|Homo sapiens unknown protein.
Length = 503
Score = 81.0 bits (191), Expect = 4e-15
Identities = 49/180 (27%), Positives = 88/180 (48%), Gaps = 1/180 (0%)
Frame = +2
Query: 2 WSTRKFDYWKRKNVPYAKPVPFFGNYMRYIT-LQSFLGDVMQKLCQQFPDRPYFGSFYGT 178
+ T +K+ +P P+PF G + Y+ L +F + +K + + G + G
Sbjct: 25 YGTHSHKLFKKLGIPGPTPLPFLGTILFYLRGLWNFDRECNEKYGEMW------GLYEGQ 78
Query: 179 EPALVLQNPEIIKQVFTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQNLTPLF 358
+P LV+ +P++IK V K+ Y + + L FA + WK IR L+P F
Sbjct: 79 QPMLVIMDPDMIKTVLVKECYSVFTNQ-MPLGPMGFLKSALSFAEDEEWKRIRTLLSPAF 137
Query: 359 SSSKMKNMFYLVEKCNHSLEDMLDKETKDLQSIEIRSAMIRYTLDSICSSAFGIETNTLS 538
+S K K M ++ +C L L +E ++ +SI ++ YT+D I + FG+ ++L+
Sbjct: 138 TSVKFKEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTMDVITGTLFGVNLDSLN 197
>M13785-1|AAA35742.1| 504|Homo sapiens protein ( Human liver
glucocorticoid-inducible cytochrome P-450 (HLp) mRNA,
complete cds. ).
Length = 504
Score = 73.7 bits (173), Expect = 6e-13
Identities = 47/180 (26%), Positives = 89/180 (49%), Gaps = 1/180 (0%)
Frame = +2
Query: 2 WSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSFLGDVMQKLCQQFPDRPYFGSFYGTE 181
+ T +K+ +P P+PF GN + Y + F M+ C + + + G + G +
Sbjct: 25 YGTHSHGLFKKLGIPGPTPLPFLGNILSYH--KGFCMFDME--CHKKYGKVW-GFYDGQQ 79
Query: 182 PALVLQNPEIIKQVFTKDFY-YFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQNLTPLF 358
P L + +P++IK V K+ Y F +RE + + A + WK +R L+P F
Sbjct: 80 PVLAITDPDMIKLVLVKECYSVFTNRE--PFGPVGFMKSAISIAEDEEWKRLRSLLSPTF 137
Query: 359 SSSKMKNMFYLVEKCNHSLEDMLDKETKDLQSIEIRSAMIRYTLDSICSSAFGIETNTLS 538
+S K+K M ++ + L L +E + + + ++ Y++D I SS+FG+ ++L+
Sbjct: 138 TSGKLKEMVPIIAQYGDVLVRNLRRERETGKPVTLKDVFGAYSMDVITSSSFGVNVDSLN 197
>D00003-1|BAA00001.1| 504|Homo sapiens cytochrome P-450 protein.
Length = 504
Score = 73.7 bits (173), Expect = 6e-13
Identities = 47/180 (26%), Positives = 89/180 (49%), Gaps = 1/180 (0%)
Frame = +2
Query: 2 WSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSFLGDVMQKLCQQFPDRPYFGSFYGTE 181
+ T +K+ +P P+PF GN + Y + F M+ C + + + G + G +
Sbjct: 25 YGTHSHGLFKKLGIPGPTPLPFLGNILSYH--KGFCMFDME--CHKKYGKVW-GFYDGQQ 79
Query: 182 PALVLQNPEIIKQVFTKDFY-YFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQNLTPLF 358
P L + +P++IK V K+ Y F +RE + + A + WK +R L+P F
Sbjct: 80 PVLAITDPDMIKLVLVKECYSVFTNRE--PFGPVGFMKSAISIAEDEEWKRLRSLLSPTF 137
Query: 359 SSSKMKNMFYLVEKCNHSLEDMLDKETKDLQSIEIRSAMIRYTLDSICSSAFGIETNTLS 538
+S K+K M ++ + L L +E + + + ++ Y++D I SS+FG+ ++L+
Sbjct: 138 TSGKLKEMVPIIAQYGDVLVRNLRRERETGKPVTLKDVFGAYSMDVITSSSFGVNVDSLN 197
>J04813-1|AAA02993.1| 502|Homo sapiens cytochrome P450 PCN3
protein.
Length = 502
Score = 73.3 bits (172), Expect = 8e-13
Identities = 47/181 (25%), Positives = 87/181 (48%), Gaps = 2/181 (1%)
Frame = +2
Query: 2 WSTRKFDYWKRKNVPYAKPVPFFGNYMRYIT-LQSFLGDVMQKLCQQFPDRPYFGSFYGT 178
+ TR +KR +P P+P GN + Y L F + +K + + G++ G
Sbjct: 25 YGTRTHGLFKRLGIPGPTPLPLLGNVLSYRQGLWKFDTECYKKYGKMW------GTYEGQ 78
Query: 179 EPALVLQNPEIIKQVFTKDFY-YFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQNLTPL 355
P L + +P++I+ V K+ Y F +R R + A + WK IR L+P
Sbjct: 79 LPVLAITDPDVIRTVLVKECYSVFTNR--RSLGPVGFMKSAISLAEDEEWKRIRSLLSPT 136
Query: 356 FSSSKMKNMFYLVEKCNHSLEDMLDKETKDLQSIEIRSAMIRYTLDSICSSAFGIETNTL 535
F+S K+K MF ++ + L L +E + + + ++ Y++D I ++FG+ ++L
Sbjct: 137 FTSGKLKEMFPIIAQYGDVLVRNLRREAEKGKPVTLKDIFGAYSMDVITGTSFGVNIDSL 196
Query: 536 S 538
+
Sbjct: 197 N 197
>DQ680079-1|ABG25922.1| 347|Homo sapiens truncated cytochrome P450,
family 3, subfamily A, polypeptide 5 protein.
Length = 347
Score = 73.3 bits (172), Expect = 8e-13
Identities = 47/181 (25%), Positives = 87/181 (48%), Gaps = 2/181 (1%)
Frame = +2
Query: 2 WSTRKFDYWKRKNVPYAKPVPFFGNYMRYIT-LQSFLGDVMQKLCQQFPDRPYFGSFYGT 178
+ TR +KR +P P+P GN + Y L F + +K + + G++ G
Sbjct: 25 YGTRTHGLFKRLGIPGPTPLPLLGNVLSYRQGLWKFDTECYKKYGKMW------GTYEGQ 78
Query: 179 EPALVLQNPEIIKQVFTKDFY-YFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQNLTPL 355
P L + +P++I+ V K+ Y F +R R + A + WK IR L+P
Sbjct: 79 LPVLAITDPDVIRTVLVKECYSVFTNR--RSLGPVGFMKSAISLAEDEEWKRIRSLLSPT 136
Query: 356 FSSSKMKNMFYLVEKCNHSLEDMLDKETKDLQSIEIRSAMIRYTLDSICSSAFGIETNTL 535
F+S K+K MF ++ + L L +E + + + ++ Y++D I ++FG+ ++L
Sbjct: 137 FTSGKLKEMFPIIAQYGDVLVRNLRREAEKGKPVTLKDIFGAYSMDVITGTSFGVNIDSL 196
Query: 536 S 538
+
Sbjct: 197 N 197
>BC033862-1|AAH33862.1| 502|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 5 protein.
Length = 502
Score = 73.3 bits (172), Expect = 8e-13
Identities = 47/181 (25%), Positives = 87/181 (48%), Gaps = 2/181 (1%)
Frame = +2
Query: 2 WSTRKFDYWKRKNVPYAKPVPFFGNYMRYIT-LQSFLGDVMQKLCQQFPDRPYFGSFYGT 178
+ TR +KR +P P+P GN + Y L F + +K + + G++ G
Sbjct: 25 YGTRTHGLFKRLGIPGPTPLPLLGNVLSYRQGLWKFDTECYKKYGKMW------GTYEGQ 78
Query: 179 EPALVLQNPEIIKQVFTKDFY-YFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQNLTPL 355
P L + +P++I+ V K+ Y F +R R + A + WK IR L+P
Sbjct: 79 LPVLAITDPDVIRTVLVKECYSVFTNR--RSLGPVGFMKSAISLAEDEEWKRIRSLLSPT 136
Query: 356 FSSSKMKNMFYLVEKCNHSLEDMLDKETKDLQSIEIRSAMIRYTLDSICSSAFGIETNTL 535
F+S K+K MF ++ + L L +E + + + ++ Y++D I ++FG+ ++L
Sbjct: 137 FTSGKLKEMFPIIAQYGDVLVRNLRREAEKGKPVTLKDIFGAYSMDVITGTSFGVNIDSL 196
Query: 536 S 538
+
Sbjct: 197 N 197
>AC005020-1|AAS02016.1| 502|Homo sapiens unknown protein.
Length = 502
Score = 73.3 bits (172), Expect = 8e-13
Identities = 47/181 (25%), Positives = 87/181 (48%), Gaps = 2/181 (1%)
Frame = +2
Query: 2 WSTRKFDYWKRKNVPYAKPVPFFGNYMRYIT-LQSFLGDVMQKLCQQFPDRPYFGSFYGT 178
+ TR +KR +P P+P GN + Y L F + +K + + G++ G
Sbjct: 25 YGTRTHGLFKRLGIPGPTPLPLLGNVLSYRQGLWKFDTECYKKYGKMW------GTYEGQ 78
Query: 179 EPALVLQNPEIIKQVFTKDFY-YFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQNLTPL 355
P L + +P++I+ V K+ Y F +R R + A + WK IR L+P
Sbjct: 79 LPVLAITDPDVIRTVLVKECYSVFTNR--RSLGPVGFMKSAISLAEDEEWKRIRSLLSPT 136
Query: 356 FSSSKMKNMFYLVEKCNHSLEDMLDKETKDLQSIEIRSAMIRYTLDSICSSAFGIETNTL 535
F+S K+K MF ++ + L L +E + + + ++ Y++D I ++FG+ ++L
Sbjct: 137 FTSGKLKEMFPIIAQYGDVLVRNLRREAEKGKPVTLKDIFGAYSMDVITGTSFGVNIDSL 196
Query: 536 S 538
+
Sbjct: 197 N 197
>X12387-1|CAA30944.1| 503|Homo sapiens protein ( Human mRNA for
cytochrome P-450 (cyp3 locus). ).
Length = 503
Score = 72.9 bits (171), Expect = 1e-12
Identities = 46/180 (25%), Positives = 89/180 (49%), Gaps = 1/180 (0%)
Frame = +2
Query: 2 WSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSFLGDVMQKLCQQFPDRPYFGSFYGTE 181
+ T +K+ +P P+PF GN + Y + F M+ C + + + G + G +
Sbjct: 25 YGTHSHGLFKKLGIPGPTPLPFLGNILSYH--KGFCMFDME--CHKKYGKVW-GFYDGQQ 79
Query: 182 PALVLQNPEIIKQVFTKDFY-YFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQNLTPLF 358
P L + +P++IK V K+ Y F +R R + + A + WK +R L+P F
Sbjct: 80 PVLAITDPDMIKTVLVKECYSVFTNR--RPFGPVGFMKSAISIAEDEEWKRLRSLLSPTF 137
Query: 359 SSSKMKNMFYLVEKCNHSLEDMLDKETKDLQSIEIRSAMIRYTLDSICSSAFGIETNTLS 538
+S K+K M ++ + L L +E + + + ++ Y++D I S++FG+ ++L+
Sbjct: 138 TSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNIDSLN 197
>M18907-1|AAA35745.1| 503|Homo sapiens protein ( Human P450 mRNA
encoding nifedipine oxidase, complete cds. ).
Length = 503
Score = 72.9 bits (171), Expect = 1e-12
Identities = 46/180 (25%), Positives = 89/180 (49%), Gaps = 1/180 (0%)
Frame = +2
Query: 2 WSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSFLGDVMQKLCQQFPDRPYFGSFYGTE 181
+ T +K+ +P P+PF GN + Y + F M+ C + + + G + G +
Sbjct: 25 YGTHSHGLFKKLGIPGPTPLPFLGNILSYH--KGFCMFDME--CHKKYGKVW-GFYDGQQ 79
Query: 182 PALVLQNPEIIKQVFTKDFY-YFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQNLTPLF 358
P L + +P++IK V K+ Y F +R R + + A + WK +R L+P F
Sbjct: 80 PVLAITDPDMIKTVLVKECYSVFTNR--RPFGPVGFMKSAISIAEDEEWKRLRSLLSPTF 137
Query: 359 SSSKMKNMFYLVEKCNHSLEDMLDKETKDLQSIEIRSAMIRYTLDSICSSAFGIETNTLS 538
+S K+K M ++ + L L +E + + + ++ Y++D I S++FG+ ++L+
Sbjct: 138 TSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNIDSLN 197
>M14096-1|AAA35744.1| 503|Homo sapiens protein ( Human cytochrome
P-450 nifedipine oxidase mRNA, complet cds. ).
Length = 503
Score = 72.9 bits (171), Expect = 1e-12
Identities = 46/180 (25%), Positives = 89/180 (49%), Gaps = 1/180 (0%)
Frame = +2
Query: 2 WSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSFLGDVMQKLCQQFPDRPYFGSFYGTE 181
+ T +K+ +P P+PF GN + Y + F M+ C + + + G + G +
Sbjct: 25 YGTHSHGLFKKLGIPGPTPLPFLGNILSYH--KGFCMFDME--CHKKYGKVW-GFYDGQQ 79
Query: 182 PALVLQNPEIIKQVFTKDFY-YFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQNLTPLF 358
P L + +P++IK V K+ Y F +R R + + A + WK +R L+P F
Sbjct: 80 PVLAITDPDMIKTVLVKECYSVFTNR--RPFGPVGFMKSAISIAEDEEWKRLRSLLSPTF 137
Query: 359 SSSKMKNMFYLVEKCNHSLEDMLDKETKDLQSIEIRSAMIRYTLDSICSSAFGIETNTLS 538
+S K+K M ++ + L L +E + + + ++ Y++D I S++FG+ ++L+
Sbjct: 138 TSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNIDSLN 197
>DQ924960-1|ABI96208.1| 503|Homo sapiens cytochrome P450 family 3
subfamily A polypeptide 4 protein.
Length = 503
Score = 72.9 bits (171), Expect = 1e-12
Identities = 46/180 (25%), Positives = 89/180 (49%), Gaps = 1/180 (0%)
Frame = +2
Query: 2 WSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSFLGDVMQKLCQQFPDRPYFGSFYGTE 181
+ T +K+ +P P+PF GN + Y + F M+ C + + + G + G +
Sbjct: 25 YGTHSHGLFKKLGIPGPTPLPFLGNILSYH--KGFCMFDME--CHKKYGKVW-GFYDGQQ 79
Query: 182 PALVLQNPEIIKQVFTKDFY-YFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQNLTPLF 358
P L + +P++IK V K+ Y F +R R + + A + WK +R L+P F
Sbjct: 80 PVLAITDPDMIKTVLVKECYSVFTNR--RPFGPVGFMKSAISIAEDEEWKRLRSLLSPTF 137
Query: 359 SSSKMKNMFYLVEKCNHSLEDMLDKETKDLQSIEIRSAMIRYTLDSICSSAFGIETNTLS 538
+S K+K M ++ + L L +E + + + ++ Y++D I S++FG+ ++L+
Sbjct: 138 TSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNIDSLN 197
>DQ005611-1|AAY16980.1| 503|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 4 protein.
Length = 503
Score = 72.9 bits (171), Expect = 1e-12
Identities = 46/180 (25%), Positives = 89/180 (49%), Gaps = 1/180 (0%)
Frame = +2
Query: 2 WSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSFLGDVMQKLCQQFPDRPYFGSFYGTE 181
+ T +K+ +P P+PF GN + Y + F M+ C + + + G + G +
Sbjct: 25 YGTHSHGLFKKLGIPGPTPLPFLGNILSYH--KGFCMFDME--CHKKYGKVW-GFYDGQQ 79
Query: 182 PALVLQNPEIIKQVFTKDFY-YFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQNLTPLF 358
P L + +P++IK V K+ Y F +R R + + A + WK +R L+P F
Sbjct: 80 PVLAITDPDMIKTVLVKECYSVFTNR--RPFGPVGFMKSAISIAEDEEWKRLRSLLSPTF 137
Query: 359 SSSKMKNMFYLVEKCNHSLEDMLDKETKDLQSIEIRSAMIRYTLDSICSSAFGIETNTLS 538
+S K+K M ++ + L L +E + + + ++ Y++D I S++FG+ ++L+
Sbjct: 138 TSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNIDSLN 197
>BC101631-1|AAI01632.1| 503|Homo sapiens cytochrome P450, subfamily
IIIA, polypeptide 4 protein.
Length = 503
Score = 72.9 bits (171), Expect = 1e-12
Identities = 46/180 (25%), Positives = 89/180 (49%), Gaps = 1/180 (0%)
Frame = +2
Query: 2 WSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSFLGDVMQKLCQQFPDRPYFGSFYGTE 181
+ T +K+ +P P+PF GN + Y + F M+ C + + + G + G +
Sbjct: 25 YGTHSHGLFKKLGIPGPTPLPFLGNILSYH--KGFCMFDME--CHKKYGKVW-GFYDGQQ 79
Query: 182 PALVLQNPEIIKQVFTKDFY-YFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQNLTPLF 358
P L + +P++IK V K+ Y F +R R + + A + WK +R L+P F
Sbjct: 80 PVLAITDPDMIKTVLVKECYSVFTNR--RPFGPVGFMKSAISIAEDEEWKRLRSLLSPTF 137
Query: 359 SSSKMKNMFYLVEKCNHSLEDMLDKETKDLQSIEIRSAMIRYTLDSICSSAFGIETNTLS 538
+S K+K M ++ + L L +E + + + ++ Y++D I S++FG+ ++L+
Sbjct: 138 TSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNIDSLN 197
>BC069418-1|AAH69418.1| 503|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 4 protein.
Length = 503
Score = 72.9 bits (171), Expect = 1e-12
Identities = 46/180 (25%), Positives = 89/180 (49%), Gaps = 1/180 (0%)
Frame = +2
Query: 2 WSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSFLGDVMQKLCQQFPDRPYFGSFYGTE 181
+ T +K+ +P P+PF GN + Y + F M+ C + + + G + G +
Sbjct: 25 YGTHSHGLFKKLGIPGPTPLPFLGNILSYH--KGFCMFDME--CHKKYGKVW-GFYDGQQ 79
Query: 182 PALVLQNPEIIKQVFTKDFY-YFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQNLTPLF 358
P L + +P++IK V K+ Y F +R R + + A + WK +R L+P F
Sbjct: 80 PVLAITDPDMIKTVLVKECYSVFTNR--RPFGPVGFMKSAISIAEDEEWKRLRSLLSPTF 137
Query: 359 SSSKMKNMFYLVEKCNHSLEDMLDKETKDLQSIEIRSAMIRYTLDSICSSAFGIETNTLS 538
+S K+K M ++ + L L +E + + + ++ Y++D I S++FG+ ++L+
Sbjct: 138 TSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNIDSLN 197
>AK223008-1|BAD96728.1| 502|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 5 variant protein.
Length = 502
Score = 72.9 bits (171), Expect = 1e-12
Identities = 47/181 (25%), Positives = 87/181 (48%), Gaps = 2/181 (1%)
Frame = +2
Query: 2 WSTRKFDYWKRKNVPYAKPVPFFGNYMRYIT-LQSFLGDVMQKLCQQFPDRPYFGSFYGT 178
+ TR +KR +P P+P GN + Y L F + +K + + G++ G
Sbjct: 25 YGTRTHGLFKRLGIPGPTPLPLLGNVLSYRQGLWKFDTECYKKYGKMW------GTYEGQ 78
Query: 179 EPALVLQNPEIIKQVFTKDFY-YFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQNLTPL 355
P L + +P++I+ V K+ Y F +R R + A + WK IR L+P
Sbjct: 79 LPVLAITDPDVIRTVLVKECYSVFTNR--RSLGPVGFMKSAISLAEDEEWKRIRPLLSPT 136
Query: 356 FSSSKMKNMFYLVEKCNHSLEDMLDKETKDLQSIEIRSAMIRYTLDSICSSAFGIETNTL 535
F+S K+K MF ++ + L L +E + + + ++ Y++D I ++FG+ ++L
Sbjct: 137 FTSGKLKEMFPIIAQYGDVLVRNLRREAEKGKPVTLKDIFGAYSMDVITGTSFGVNIDSL 196
Query: 536 S 538
+
Sbjct: 197 N 197
>AJ563375-1|CAD91343.1| 503|Homo sapiens cytochrome P450 protein.
Length = 503
Score = 72.9 bits (171), Expect = 1e-12
Identities = 46/180 (25%), Positives = 89/180 (49%), Gaps = 1/180 (0%)
Frame = +2
Query: 2 WSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSFLGDVMQKLCQQFPDRPYFGSFYGTE 181
+ T +K+ +P P+PF GN + Y + F M+ C + + + G + G +
Sbjct: 25 YGTHSHGLFKKLGIPGPTPLPFLGNILSYH--KGFCMFDME--CHKKYGKVW-GFYDGQQ 79
Query: 182 PALVLQNPEIIKQVFTKDFY-YFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQNLTPLF 358
P L + +P++IK V K+ Y F +R R + + A + WK +R L+P F
Sbjct: 80 PVLAITDPDMIKTVLVKECYSVFTNR--RPFGPVGFMKSAISIAEDEEWKRLRSLLSPTF 137
Query: 359 SSSKMKNMFYLVEKCNHSLEDMLDKETKDLQSIEIRSAMIRYTLDSICSSAFGIETNTLS 538
+S K+K M ++ + L L +E + + + ++ Y++D I S++FG+ ++L+
Sbjct: 138 TSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNIDSLN 197
>AF280107-2|AAG32290.1| 503|Homo sapiens cytochrome P450
polypeptide 4 protein.
Length = 503
Score = 72.9 bits (171), Expect = 1e-12
Identities = 46/180 (25%), Positives = 89/180 (49%), Gaps = 1/180 (0%)
Frame = +2
Query: 2 WSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSFLGDVMQKLCQQFPDRPYFGSFYGTE 181
+ T +K+ +P P+PF GN + Y + F M+ C + + + G + G +
Sbjct: 25 YGTHSHGLFKKLGIPGPTPLPFLGNILSYH--KGFCMFDME--CHKKYGKVW-GFYDGQQ 79
Query: 182 PALVLQNPEIIKQVFTKDFY-YFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQNLTPLF 358
P L + +P++IK V K+ Y F +R R + + A + WK +R L+P F
Sbjct: 80 PVLAITDPDMIKTVLVKECYSVFTNR--RPFGPVGFMKSAISIAEDEEWKRLRSLLSPTF 137
Query: 359 SSSKMKNMFYLVEKCNHSLEDMLDKETKDLQSIEIRSAMIRYTLDSICSSAFGIETNTLS 538
+S K+K M ++ + L L +E + + + ++ Y++D I S++FG+ ++L+
Sbjct: 138 TSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNIDSLN 197
>AF209389-1|AAF21034.1| 503|Homo sapiens cytochrome P450 IIIA4
protein.
Length = 503
Score = 72.9 bits (171), Expect = 1e-12
Identities = 46/180 (25%), Positives = 89/180 (49%), Gaps = 1/180 (0%)
Frame = +2
Query: 2 WSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSFLGDVMQKLCQQFPDRPYFGSFYGTE 181
+ T +K+ +P P+PF GN + Y + F M+ C + + + G + G +
Sbjct: 25 YGTHSHGLFKKLGIPGPTPLPFLGNILSYH--KGFCMFDME--CHKKYGKVW-GFYDGQQ 79
Query: 182 PALVLQNPEIIKQVFTKDFY-YFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQNLTPLF 358
P L + +P++IK V K+ Y F +R R + + A + WK +R L+P F
Sbjct: 80 PVLAITDPDMIKTVLVKECYSVFTNR--RPFGPVGFMKSAISIAEDEEWKRLRSLLSPTF 137
Query: 359 SSSKMKNMFYLVEKCNHSLEDMLDKETKDLQSIEIRSAMIRYTLDSICSSAFGIETNTLS 538
+S K+K M ++ + L L +E + + + ++ Y++D I S++FG+ ++L+
Sbjct: 138 TSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNIDSLN 197
>AF182273-1|AAF13598.1| 503|Homo sapiens cytochrome P450-3A4
protein.
Length = 503
Score = 72.9 bits (171), Expect = 1e-12
Identities = 46/180 (25%), Positives = 89/180 (49%), Gaps = 1/180 (0%)
Frame = +2
Query: 2 WSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSFLGDVMQKLCQQFPDRPYFGSFYGTE 181
+ T +K+ +P P+PF GN + Y + F M+ C + + + G + G +
Sbjct: 25 YGTHSHGLFKKLGIPGPTPLPFLGNILSYH--KGFCMFDME--CHKKYGKVW-GFYDGQQ 79
Query: 182 PALVLQNPEIIKQVFTKDFY-YFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQNLTPLF 358
P L + +P++IK V K+ Y F +R R + + A + WK +R L+P F
Sbjct: 80 PVLAITDPDMIKTVLVKECYSVFTNR--RPFGPVGFMKSAISIAEDEEWKRLRSLLSPTF 137
Query: 359 SSSKMKNMFYLVEKCNHSLEDMLDKETKDLQSIEIRSAMIRYTLDSICSSAFGIETNTLS 538
+S K+K M ++ + L L +E + + + ++ Y++D I S++FG+ ++L+
Sbjct: 138 TSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNIDSLN 197
>J04449-1|AAA35747.1| 502|Homo sapiens cytochrome P450 nifedipine
oxidase protein.
Length = 502
Score = 71.7 bits (168), Expect = 2e-12
Identities = 46/180 (25%), Positives = 88/180 (48%), Gaps = 1/180 (0%)
Frame = +2
Query: 2 WSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSFLGDVMQKLCQQFPDRPYFGSFYGTE 181
+ T +K+ +P P+PF GN + Y + F M+ C + + G + G +
Sbjct: 25 YGTHSHGLFKKLGIPGPTPLPFLGNILSYH--KGFCMFDME--CHKKYGK-VCGFYDGQQ 79
Query: 182 PALVLQNPEIIKQVFTKDFY-YFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQNLTPLF 358
P L + +P++IK V K+ Y F +R R + + A + WK +R L+P F
Sbjct: 80 PVLAITDPDMIKTVLVKECYSVFTNR--RPFGPVGFMKSAISIAEDEEWKRLRSLLSPTF 137
Query: 359 SSSKMKNMFYLVEKCNHSLEDMLDKETKDLQSIEIRSAMIRYTLDSICSSAFGIETNTLS 538
+S K+K M ++ + L L +E + + + ++ Y++D I S++FG+ ++L+
Sbjct: 138 TSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNIDSLN 197
>D00408-1|BAA00310.1| 503|Homo sapiens cytochrome P-450 HFLa
protein.
Length = 503
Score = 69.7 bits (163), Expect = 1e-11
Identities = 46/180 (25%), Positives = 89/180 (49%), Gaps = 1/180 (0%)
Frame = +2
Query: 2 WSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSFLGDVMQKLCQQFPDRPYFGSFYGTE 181
+ TR +K+ +P P+PF GN + + + + M+ C + R +G + +
Sbjct: 25 YGTRTHGLFKKLGIPGPTPLPFLGNALSF--RKGYWTFDME--CYK-KYRKVWGIYDCQQ 79
Query: 182 PALVLQNPEIIKQVFTKDFY-YFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQNLTPLF 358
P L + +P++IK V K+ Y F +R R + + A + WK IR L+P F
Sbjct: 80 PMLAITDPDMIKTVLVKECYSVFTNR--RPFGPVGFMKNAISIAEDEEWKRIRSLLSPTF 137
Query: 359 SSSKMKNMFYLVEKCNHSLEDMLDKETKDLQSIEIRSAMIRYTLDSICSSAFGIETNTLS 538
+S K+K M ++ + L L +E + + + ++ Y++D I S++FG+ ++L+
Sbjct: 138 TSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKHVFGAYSMDVITSTSFGVSIDSLN 197
>BC067436-1|AAH67436.1| 503|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 7 protein.
Length = 503
Score = 69.7 bits (163), Expect = 1e-11
Identities = 46/180 (25%), Positives = 89/180 (49%), Gaps = 1/180 (0%)
Frame = +2
Query: 2 WSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSFLGDVMQKLCQQFPDRPYFGSFYGTE 181
+ TR +K+ +P P+PF GN + + + + M+ C + R +G + +
Sbjct: 25 YGTRTHGLFKKLGIPGPTPLPFLGNALSF--RKGYWTFDME--CYK-KYRKVWGIYDCQQ 79
Query: 182 PALVLQNPEIIKQVFTKDFY-YFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQNLTPLF 358
P L + +P++IK V K+ Y F +R R + + A + WK IR L+P F
Sbjct: 80 PMLAITDPDMIKTVLVKECYSVFTNR--RPFGPVGFMKNAISIAEDEEWKRIRSLLSPTF 137
Query: 359 SSSKMKNMFYLVEKCNHSLEDMLDKETKDLQSIEIRSAMIRYTLDSICSSAFGIETNTLS 538
+S K+K M ++ + L L +E + + + ++ Y++D I S++FG+ ++L+
Sbjct: 138 TSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKHVFGAYSMDVITSTSFGVSIDSLN 197
>AF315325-1|AAG48618.1| 535|Homo sapiens cytochrome P450 variant
3A7 protein.
Length = 535
Score = 69.7 bits (163), Expect = 1e-11
Identities = 46/180 (25%), Positives = 89/180 (49%), Gaps = 1/180 (0%)
Frame = +2
Query: 2 WSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSFLGDVMQKLCQQFPDRPYFGSFYGTE 181
+ TR +K+ +P P+PF GN + + + + M+ C + R +G + +
Sbjct: 25 YGTRTHGLFKKLGIPGPTPLPFLGNALSF--RKGYWTFDME--CYK-KYRKVWGIYDCQQ 79
Query: 182 PALVLQNPEIIKQVFTKDFY-YFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQNLTPLF 358
P L + +P++IK V K+ Y F +R R + + A + WK IR L+P F
Sbjct: 80 PMLAITDPDMIKTVLVKECYSVFTNR--RPFGPVGFMKNAISIAEDEEWKRIRSLLSPTF 137
Query: 359 SSSKMKNMFYLVEKCNHSLEDMLDKETKDLQSIEIRSAMIRYTLDSICSSAFGIETNTLS 538
+S K+K M ++ + L L +E + + + ++ Y++D I S++FG+ ++L+
Sbjct: 138 TSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKHVFGAYSMDVITSTSFGVSIDSLN 197
>AF280107-3|AAG32289.1| 503|Homo sapiens cytochrome P450
polypeptide 7 protein.
Length = 503
Score = 69.7 bits (163), Expect = 1e-11
Identities = 46/180 (25%), Positives = 89/180 (49%), Gaps = 1/180 (0%)
Frame = +2
Query: 2 WSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSFLGDVMQKLCQQFPDRPYFGSFYGTE 181
+ TR +K+ +P P+PF GN + + + + M+ C + R +G + +
Sbjct: 25 YGTRTHGLFKKLGIPGPTPLPFLGNALSF--RKGYWTFDME--CYK-KYRKVWGIYDCQQ 79
Query: 182 PALVLQNPEIIKQVFTKDFY-YFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQNLTPLF 358
P L + +P++IK V K+ Y F +R R + + A + WK IR L+P F
Sbjct: 80 PMLAITDPDMIKTVLVKECYSVFTNR--RPFGPVGFMKNAISIAEDEEWKRIRSLLSPTF 137
Query: 359 SSSKMKNMFYLVEKCNHSLEDMLDKETKDLQSIEIRSAMIRYTLDSICSSAFGIETNTLS 538
+S K+K M ++ + L L +E + + + ++ Y++D I S++FG+ ++L+
Sbjct: 138 TSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKHVFGAYSMDVITSTSFGVSIDSLN 197
>AC004914-1|AAD21788.1| 348|Homo sapiens unknown protein.
Length = 348
Score = 68.9 bits (161), Expect = 2e-11
Identities = 59/218 (27%), Positives = 93/218 (42%)
Frame = +2
Query: 2 WSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSFLGDVMQKLCQQFPDRPYFGSFYGTE 181
+ST F ++ + + KP PF GN + Q F M+ L + + P G + G
Sbjct: 1 YSTSAFSRLEKLGLRHPKPSPFIGNLTFF--RQGFWESQME-LRKLYG--PLCGYYLGRR 55
Query: 182 PALVLQNPEIIKQVFTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQNLTPLFS 361
+V+ P++IKQV ++F F +R K V ++ F RW+ +R L FS
Sbjct: 56 MFIVISEPDMIKQVLVENFSNFTNRMASGLEFKSV-ADSVLFLRDKRWEEVRGALMSAFS 114
Query: 362 SSKMKNMFYLVEKCNHSLEDMLDKETKDLQSIEIRSAMIRYTLDSICSSAFGIETNTLSE 541
K+ M L+ + L L + + + +I+ YT D + S AFG T S
Sbjct: 115 PEKLNEMVPLISQACELLLAHLKRYAESGDAFDIQRCYCNYTTDVVASVAFG--TPVDSW 172
Query: 542 GAENSPFPSMGSTIFSSSITRGLKLIGRSMWPGIFYKL 655
A PF F I R + ++ S +P I L
Sbjct: 173 QAPEDPFVKHCKRFFEFCIPRPILVLLLS-FPSIMVPL 209
>D34625-1|BAA07011.1| 533|Homo sapiens thromboxane synthase
protein.
Length = 533
Score = 68.5 bits (160), Expect = 2e-11
Identities = 59/218 (27%), Positives = 93/218 (42%)
Frame = +2
Query: 2 WSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSFLGDVMQKLCQQFPDRPYFGSFYGTE 181
+ST F ++ + + KP PF GN + Q F M+ L + + P G + G
Sbjct: 31 YSTSAFSRLEKLGLRHPKPSPFIGNLTFF--RQGFWESQME-LRKLYG--PLCGYYLGRR 85
Query: 182 PALVLQNPEIIKQVFTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQNLTPLFS 361
+V+ P++IKQV ++F F +R K V ++ F RW+ +R L FS
Sbjct: 86 MFIVISEPDMIKQVLVENFSNFTNRMASGLEFKSV-ADSVLFLRDKRWEEVRGALMSAFS 144
Query: 362 SSKMKNMFYLVEKCNHSLEDMLDKETKDLQSIEIRSAMIRYTLDSICSSAFGIETNTLSE 541
K+ M L+ + L L + + + +I+ YT D + S AFG T S
Sbjct: 145 PEKLNEMVPLISQACDLLLAHLKRYAESGDAFDIQRCYCNYTTDVVASVAFG--TPVDSW 202
Query: 542 GAENSPFPSMGSTIFSSSITRGLKLIGRSMWPGIFYKL 655
A PF F I R + ++ S +P I L
Sbjct: 203 QAPEDPFVKHCKRFFEFCIPRPILVLLLS-FPSIMVPL 239
>BC041157-1|AAH41157.1| 534|Homo sapiens thromboxane A synthase 1
(platelet, cytochrome P450, family 5, subfamily A)
protein.
Length = 534
Score = 68.5 bits (160), Expect = 2e-11
Identities = 59/218 (27%), Positives = 93/218 (42%)
Frame = +2
Query: 2 WSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSFLGDVMQKLCQQFPDRPYFGSFYGTE 181
+ST F ++ + + KP PF GN + Q F M+ L + + P G + G
Sbjct: 32 YSTSAFSRLEKLGLRHPKPSPFIGNLTFF--RQGFWESQME-LRKLYG--PLCGYYLGRR 86
Query: 182 PALVLQNPEIIKQVFTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQNLTPLFS 361
+V+ P++IKQV ++F F +R K V ++ F RW+ +R L FS
Sbjct: 87 MFIVISEPDMIKQVLVENFSNFTNRMASGLEFKSV-ADSVLFLRDKRWEEVRGALMSAFS 145
Query: 362 SSKMKNMFYLVEKCNHSLEDMLDKETKDLQSIEIRSAMIRYTLDSICSSAFGIETNTLSE 541
K+ M L+ + L L + + + +I+ YT D + S AFG T S
Sbjct: 146 PEKLNEMVPLISQACDLLLAHLKRYAESGDAFDIQRCYCNYTTDVVASVAFG--TPVDSW 203
Query: 542 GAENSPFPSMGSTIFSSSITRGLKLIGRSMWPGIFYKL 655
A PF F I R + ++ S +P I L
Sbjct: 204 QAPEDPFVKHCKRFFEFCIPRPILVLLLS-FPSIMVPL 240
>AK223466-1|BAD97186.1| 534|Homo sapiens thromboxane A synthase 1
(platelet, cytochrome P450, family 5, subfamily A) iso
protein.
Length = 534
Score = 68.5 bits (160), Expect = 2e-11
Identities = 59/218 (27%), Positives = 93/218 (42%)
Frame = +2
Query: 2 WSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSFLGDVMQKLCQQFPDRPYFGSFYGTE 181
+ST F ++ + + KP PF GN + Q F M+ L + + P G + G
Sbjct: 32 YSTSAFSRLEKLGLRHPKPSPFIGNLTFF--RQGFWESQME-LRKLYG--PLCGYYLGRR 86
Query: 182 PALVLQNPEIIKQVFTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQNLTPLFS 361
+V+ P++IKQV ++F F +R K V ++ F RW+ +R L FS
Sbjct: 87 MFIVISEPDMIKQVLVENFSNFTNRMASGLEFKSV-ADSVLFLRDKRWEEVRGALMSAFS 145
Query: 362 SSKMKNMFYLVEKCNHSLEDMLDKETKDLQSIEIRSAMIRYTLDSICSSAFGIETNTLSE 541
K+ M L+ + L L + + + +I+ YT D + S AFG T S
Sbjct: 146 PEKLNEMVPLISQACDLLLAHLKRYAESGDAFDIQRCYCNYTTDVVASVAFG--TPVDSW 203
Query: 542 GAENSPFPSMGSTIFSSSITRGLKLIGRSMWPGIFYKL 655
A PF F I R + ++ S +P I L
Sbjct: 204 QAPEDPFVKHCKRFFEFCIPRPILVLLLS-FPSIMVPL 240
>AF233619-1|AAF99273.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 66.9 bits (156), Expect = 7e-11
Identities = 58/218 (26%), Positives = 92/218 (42%)
Frame = +2
Query: 2 WSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSFLGDVMQKLCQQFPDRPYFGSFYGTE 181
+ST F ++ + + KP PF GN + Q F M+ L + + P G + G
Sbjct: 32 YSTSAFSRLEKLGLRHPKPSPFIGNLTFF--RQGFWESQME-LRKLY--GPLCGYYLGRR 86
Query: 182 PALVLQNPEIIKQVFTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQNLTPLFS 361
+V+ P++IKQV ++F F +R K V ++ F RW+ +R L FS
Sbjct: 87 MFIVISEPDMIKQVLVENFSNFTNRMASGLEFKSV-ADSVLFLRDKRWEEVRGALMSAFS 145
Query: 362 SSKMKNMFYLVEKCNHSLEDMLDKETKDLQSIEIRSAMIRYTLDSICSSAFGIETNTLSE 541
K+ M L+ + L L + + + +I+ YT D + S FG T S
Sbjct: 146 PEKLNEMVPLISQACELLLAHLKRYAESGDAFDIQRCYCNYTTDVVASVPFG--TPVDSW 203
Query: 542 GAENSPFPSMGSTIFSSSITRGLKLIGRSMWPGIFYKL 655
A PF F I R + ++ S +P I L
Sbjct: 204 QAPEDPFVKHCKRFFEFCIPRPILVLLLS-FPSIMVPL 240
>M80647-1|AAA60618.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 66.5 bits (155), Expect = 9e-11
Identities = 58/218 (26%), Positives = 92/218 (42%)
Frame = +2
Query: 2 WSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSFLGDVMQKLCQQFPDRPYFGSFYGTE 181
+ST F ++ + + KP PF GN + Q F M+ L + + P G + G
Sbjct: 32 YSTSAFSRLEKLGLRHPKPSPFIGNLTFF--RQGFWESQME-LRKLY--GPLCGYYLGRR 86
Query: 182 PALVLQNPEIIKQVFTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQNLTPLFS 361
+V+ P++IKQV ++F F +R K V ++ F RW+ +R L FS
Sbjct: 87 MFIVISEPDMIKQVLVENFSNFTNRMASGLEFKSV-ADSVLFLRDKRWEEVRGALMSAFS 145
Query: 362 SSKMKNMFYLVEKCNHSLEDMLDKETKDLQSIEIRSAMIRYTLDSICSSAFGIETNTLSE 541
K+ M L+ + L L + + + +I+ YT D + S FG T S
Sbjct: 146 PEKLNEMVPLISQACDLLLAHLKRYAESGDAFDIQRCYCNYTTDVVASVPFG--TPVDSW 203
Query: 542 GAENSPFPSMGSTIFSSSITRGLKLIGRSMWPGIFYKL 655
A PF F I R + ++ S +P I L
Sbjct: 204 QAPEDPFVKHCKRFFEFCIPRPILVLLLS-FPSIMVPL 240
>M80646-1|AAA60617.1| 460|Homo sapiens thromboxane synthase
protein.
Length = 460
Score = 66.5 bits (155), Expect = 9e-11
Identities = 58/218 (26%), Positives = 92/218 (42%)
Frame = +2
Query: 2 WSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSFLGDVMQKLCQQFPDRPYFGSFYGTE 181
+ST F ++ + + KP PF GN + Q F M+ L + + P G + G
Sbjct: 32 YSTSAFSRLEKLGLRHPKPSPFIGNLTFF--RQGFWESQME-LRKLY--GPLCGYYLGRR 86
Query: 182 PALVLQNPEIIKQVFTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQNLTPLFS 361
+V+ P++IKQV ++F F +R K V ++ F RW+ +R L FS
Sbjct: 87 MFIVISEPDMIKQVLVENFSNFTNRMASGLEFKSV-ADSVLFLRDKRWEEVRGALMSAFS 145
Query: 362 SSKMKNMFYLVEKCNHSLEDMLDKETKDLQSIEIRSAMIRYTLDSICSSAFGIETNTLSE 541
K+ M L+ + L L + + + +I+ YT D + S FG T S
Sbjct: 146 PEKLNEMVPLISQACDLLLAHLKRYAESGDAFDIQRCYCNYTTDVVASVPFG--TPVDSW 203
Query: 542 GAENSPFPSMGSTIFSSSITRGLKLIGRSMWPGIFYKL 655
A PF F I R + ++ S +P I L
Sbjct: 204 QAPEDPFVKHCKRFFEFCIPRPILVLLLS-FPSIMVPL 240
>M74055-1|AAA36742.1| 229|Homo sapiens thromboxane synthase
protein.
Length = 229
Score = 66.5 bits (155), Expect = 9e-11
Identities = 58/218 (26%), Positives = 92/218 (42%)
Frame = +2
Query: 2 WSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSFLGDVMQKLCQQFPDRPYFGSFYGTE 181
+ST F ++ + + KP PF GN + Q F M+ L + + P G + G
Sbjct: 16 YSTSAFSRLEKLGLRHPKPSPFIGNLTFF--RQGFWESQME-LRKLY--GPLCGYYLGRR 70
Query: 182 PALVLQNPEIIKQVFTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQNLTPLFS 361
+V+ P++IKQV ++F F +R K V ++ F RW+ +R L FS
Sbjct: 71 MFIVISEPDMIKQVLVQNFSNFTNRMASGLEFKSV-ADSVLFLRDKRWEEVRGALMSAFS 129
Query: 362 SSKMKNMFYLVEKCNHSLEDMLDKETKDLQSIEIRSAMIRYTLDSICSSAFGIETNTLSE 541
K+ M L+ + L L + + + +I+ YT D + S FG T S
Sbjct: 130 PEKLNEMVPLISQACDLLLAHLKRYAESGDAFDIQRCYCNYTTDVVASVPFG--TPVDSW 187
Query: 542 GAENSPFPSMGSTIFSSSITRGLKLIGRSMWPGIFYKL 655
A PF F I R + ++ S +P I L
Sbjct: 188 QAPEDPFVKHCKRFFEFCIPRPILVLLLS-FPSIMVPL 224
>AF233625-1|AAF99279.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 66.5 bits (155), Expect = 9e-11
Identities = 58/218 (26%), Positives = 92/218 (42%)
Frame = +2
Query: 2 WSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSFLGDVMQKLCQQFPDRPYFGSFYGTE 181
+ST F ++ + + KP PF GN + Q F M+ L + + P G + G
Sbjct: 32 YSTSAFSRLEKLGLRHPKPSPFIGNLTFF--RQGFWESQME-LRKLY--GPLCGYYLGRR 86
Query: 182 PALVLQNPEIIKQVFTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQNLTPLFS 361
+V+ P++IKQV ++F F +R K V ++ F RW+ +R L FS
Sbjct: 87 MFIVISEPDMIKQVLVENFSNFTNRMASGLEFKSV-ADSVLFLRDKRWEEVRGALMSAFS 145
Query: 362 SSKMKNMFYLVEKCNHSLEDMLDKETKDLQSIEIRSAMIRYTLDSICSSAFGIETNTLSE 541
K+ M L+ + L L + + + +I+ YT D + S FG T S
Sbjct: 146 PEKLNEMVPLISQACDLLLAHLKRYAESGDAFDIQRCYCNYTTDVVASVPFG--TPVDSW 203
Query: 542 GAENSPFPSMGSTIFSSSITRGLKLIGRSMWPGIFYKL 655
A PF F I R + ++ S +P I L
Sbjct: 204 QAPEDPFVKHCKRFFEFCIPRPILVLLLS-FPSIMVPL 240
>AF233624-1|AAF99278.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 66.5 bits (155), Expect = 9e-11
Identities = 58/218 (26%), Positives = 92/218 (42%)
Frame = +2
Query: 2 WSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSFLGDVMQKLCQQFPDRPYFGSFYGTE 181
+ST F ++ + + KP PF GN + Q F M+ L + + P G + G
Sbjct: 32 YSTSAFSRLEKLGLRHPKPSPFIGNLTFF--RQGFWESQME-LRKLY--GPLCGYYLGRR 86
Query: 182 PALVLQNPEIIKQVFTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQNLTPLFS 361
+V+ P++IKQV ++F F +R K V ++ F RW+ +R L FS
Sbjct: 87 MFIVISEPDMIKQVLVENFSNFTNRMASGLEFKSV-ADSVLFLRDKRWEEVRGALMSAFS 145
Query: 362 SSKMKNMFYLVEKCNHSLEDMLDKETKDLQSIEIRSAMIRYTLDSICSSAFGIETNTLSE 541
K+ M L+ + L L + + + +I+ YT D + S FG T S
Sbjct: 146 PEKLNEMVPLISQACDLLLAHLKRYAESGDAFDIQRCYCNYTTDVVASVPFG--TPVDSW 203
Query: 542 GAENSPFPSMGSTIFSSSITRGLKLIGRSMWPGIFYKL 655
A PF F I R + ++ S +P I L
Sbjct: 204 QAPEDPFVKHCKRFFEFCIPRPILVLLLS-FPSIMVPL 240
>AF233623-1|AAF99277.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 66.5 bits (155), Expect = 9e-11
Identities = 58/218 (26%), Positives = 92/218 (42%)
Frame = +2
Query: 2 WSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSFLGDVMQKLCQQFPDRPYFGSFYGTE 181
+ST F ++ + + KP PF GN + Q F M+ L + + P G + G
Sbjct: 32 YSTSAFSRLEKLGLRHPKPSPFIGNLTFF--RQGFWESQME-LRKLY--GPLCGYYLGRR 86
Query: 182 PALVLQNPEIIKQVFTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQNLTPLFS 361
+V+ P++IKQV ++F F +R K V ++ F RW+ +R L FS
Sbjct: 87 MFIVISEPDMIKQVLVENFSNFTNRMASGLEFKSV-ADSVLFLRDKRWEEVRGALMSAFS 145
Query: 362 SSKMKNMFYLVEKCNHSLEDMLDKETKDLQSIEIRSAMIRYTLDSICSSAFGIETNTLSE 541
K+ M L+ + L L + + + +I+ YT D + S FG T S
Sbjct: 146 PEKLNEMVPLISQACDLLLAHLKRYAESGDAFDIQRCYCNYTTDVVASVPFG--TPVDSW 203
Query: 542 GAENSPFPSMGSTIFSSSITRGLKLIGRSMWPGIFYKL 655
A PF F I R + ++ S +P I L
Sbjct: 204 QAPEDPFVKHCKRFFEFCIPRPILVLLLS-FPSIMVPL 240
>AF233622-1|AAF99276.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 66.5 bits (155), Expect = 9e-11
Identities = 58/218 (26%), Positives = 92/218 (42%)
Frame = +2
Query: 2 WSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSFLGDVMQKLCQQFPDRPYFGSFYGTE 181
+ST F ++ + + KP PF GN + Q F M+ L + + P G + G
Sbjct: 32 YSTSAFSRLEKLGLRHPKPSPFIGNLTFF--RQGFWESQME-LRKLY--GPLCGYYLGRR 86
Query: 182 PALVLQNPEIIKQVFTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQNLTPLFS 361
+V+ P++IKQV ++F F +R K V ++ F RW+ +R L FS
Sbjct: 87 MFIVISEPDMIKQVLVENFSNFTNRMASGLEFKSV-ADSVLFLRDKRWEEVRGALMSAFS 145
Query: 362 SSKMKNMFYLVEKCNHSLEDMLDKETKDLQSIEIRSAMIRYTLDSICSSAFGIETNTLSE 541
K+ M L+ + L L + + + +I+ YT D + S FG T S
Sbjct: 146 PEKLNEMVPLISQACDLLLAHLKRYAESGDAFDIQRCYCNYTTDVVASVPFG--TPVDSW 203
Query: 542 GAENSPFPSMGSTIFSSSITRGLKLIGRSMWPGIFYKL 655
A PF F I R + ++ S +P I L
Sbjct: 204 QAPEDPFVKHCKRFFEFCIPRPILVLLLS-FPSIMVPL 240
>AF233621-1|AAF99275.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 66.5 bits (155), Expect = 9e-11
Identities = 58/218 (26%), Positives = 92/218 (42%)
Frame = +2
Query: 2 WSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSFLGDVMQKLCQQFPDRPYFGSFYGTE 181
+ST F ++ + + KP PF GN + Q F M+ L + + P G + G
Sbjct: 32 YSTSAFSRLEKLGLRHPKPSPFIGNLTFF--RQGFWESQME-LRKLY--GPLCGYYLGRR 86
Query: 182 PALVLQNPEIIKQVFTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQNLTPLFS 361
+V+ P++IKQV ++F F +R K V ++ F RW+ +R L FS
Sbjct: 87 MFIVISEPDMIKQVLVENFSNFTNRMASGLEFKSV-ADSVLFLRDKRWEEVRGALMSAFS 145
Query: 362 SSKMKNMFYLVEKCNHSLEDMLDKETKDLQSIEIRSAMIRYTLDSICSSAFGIETNTLSE 541
K+ M L+ + L L + + + +I+ YT D + S FG T S
Sbjct: 146 PEKLNEMVPLISQACDLLLAHLKRYAESGDAFDIQRCYCNYTTDVVASVPFG--TPVDSW 203
Query: 542 GAENSPFPSMGSTIFSSSITRGLKLIGRSMWPGIFYKL 655
A PF F I R + ++ S +P I L
Sbjct: 204 QAPEDPFVKHCKRFFEFCIPRPILVLLLS-FPSIMVPL 240
>AF233620-1|AAF99274.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 66.5 bits (155), Expect = 9e-11
Identities = 58/218 (26%), Positives = 92/218 (42%)
Frame = +2
Query: 2 WSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSFLGDVMQKLCQQFPDRPYFGSFYGTE 181
+ST F ++ + + KP PF GN + Q F M+ L + + P G + G
Sbjct: 32 YSTSAFSRLEKLGLRHPKPSPFIGNLTFF--RQGFWESQME-LRKLY--GPLCGYYLGRR 86
Query: 182 PALVLQNPEIIKQVFTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQNLTPLFS 361
+V+ P++IKQV ++F F +R K V ++ F RW+ +R L FS
Sbjct: 87 MFIVISEPDMIKQVLVENFSNFTNRMASGLEFKSV-ADSVLFLRDKRWEEVRGALMSAFS 145
Query: 362 SSKMKNMFYLVEKCNHSLEDMLDKETKDLQSIEIRSAMIRYTLDSICSSAFGIETNTLSE 541
K+ M L+ + L L + + + +I+ YT D + S FG T S
Sbjct: 146 PEKLNEMVPLISQACDLLLAHLKRYAESGDAFDIQRCYCNYTTDVVASVPFG--TPVDSW 203
Query: 542 GAENSPFPSMGSTIFSSSITRGLKLIGRSMWPGIFYKL 655
A PF F I R + ++ S +P I L
Sbjct: 204 QAPEDPFVKHCKRFFEFCIPRPILVLLLS-FPSIMVPL 240
>AF233617-1|AAF99271.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 66.5 bits (155), Expect = 9e-11
Identities = 58/218 (26%), Positives = 92/218 (42%)
Frame = +2
Query: 2 WSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSFLGDVMQKLCQQFPDRPYFGSFYGTE 181
+ST F ++ + + KP PF GN + Q F M+ L + + P G + G
Sbjct: 32 YSTSAFSRLEKLGLRHPKPSPFIGNLTFF--RQGFWESQME-LRKLY--GPLCGYYLGRR 86
Query: 182 PALVLQNPEIIKQVFTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQNLTPLFS 361
+V+ P++IKQV ++F F +R K V ++ F RW+ +R L FS
Sbjct: 87 MFIVISEPDMIKQVLVENFSNFTNRMASGLEFKSV-ADSVLFLRDKRWEEVRGALMSAFS 145
Query: 362 SSKMKNMFYLVEKCNHSLEDMLDKETKDLQSIEIRSAMIRYTLDSICSSAFGIETNTLSE 541
K+ M L+ + L L + + + +I+ YT D + S FG T S
Sbjct: 146 PEKLNEMVPLISQACDLLLAHLKRYAESGDAFDIQRCYCNYTTDVVASVPFG--TPVDSW 203
Query: 542 GAENSPFPSMGSTIFSSSITRGLKLIGRSMWPGIFYKL 655
A PF F I R + ++ S +P I L
Sbjct: 204 QAPEDPFVKHCKRFFEFCIPRPILVLLLS-FPSIMVPL 240
>AF233616-1|AAF99270.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 66.5 bits (155), Expect = 9e-11
Identities = 58/218 (26%), Positives = 92/218 (42%)
Frame = +2
Query: 2 WSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSFLGDVMQKLCQQFPDRPYFGSFYGTE 181
+ST F ++ + + KP PF GN + Q F M+ L + + P G + G
Sbjct: 32 YSTSAFSRLEKLGLRHPKPSPFIGNLTFF--RQGFWESQME-LRKLY--GPLCGYYLGRR 86
Query: 182 PALVLQNPEIIKQVFTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQNLTPLFS 361
+V+ P++IKQV ++F F +R K V ++ F RW+ +R L FS
Sbjct: 87 MFIVISEPDMIKQVLVENFSNFTNRMASGLEFKSV-ADSVLFLRDKRWEEVRGALMSAFS 145
Query: 362 SSKMKNMFYLVEKCNHSLEDMLDKETKDLQSIEIRSAMIRYTLDSICSSAFGIETNTLSE 541
K+ M L+ + L L + + + +I+ YT D + S FG T S
Sbjct: 146 PEKLNEMVPLISQACDLLLAHLKRYAESGDAFDIQRCYCNYTTDVVASVPFG--TPVDSW 203
Query: 542 GAENSPFPSMGSTIFSSSITRGLKLIGRSMWPGIFYKL 655
A PF F I R + ++ S +P I L
Sbjct: 204 QAPEDPFVKHCKRFFEFCIPRPILVLLLS-FPSIMVPL 240
>AF233615-1|AAF99269.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 66.5 bits (155), Expect = 9e-11
Identities = 58/218 (26%), Positives = 92/218 (42%)
Frame = +2
Query: 2 WSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSFLGDVMQKLCQQFPDRPYFGSFYGTE 181
+ST F ++ + + KP PF GN + Q F M+ L + + P G + G
Sbjct: 32 YSTSAFSRLEKLGLRHPKPSPFIGNLTFF--RQGFWESQME-LRKLY--GPLCGYYLGRR 86
Query: 182 PALVLQNPEIIKQVFTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQNLTPLFS 361
+V+ P++IKQV ++F F +R K V ++ F RW+ +R L FS
Sbjct: 87 MFIVISEPDMIKQVLVENFSNFTNRMASGLEFKSV-ADSVLFLRDKRWEEVRGALMSAFS 145
Query: 362 SSKMKNMFYLVEKCNHSLEDMLDKETKDLQSIEIRSAMIRYTLDSICSSAFGIETNTLSE 541
K+ M L+ + L L + + + +I+ YT D + S FG T S
Sbjct: 146 PEKLNEMVPLISQACDLLLAHLKRYAESGDAFDIQRCYCNYTTDVVASVPFG--TPVDSW 203
Query: 542 GAENSPFPSMGSTIFSSSITRGLKLIGRSMWPGIFYKL 655
A PF F I R + ++ S +P I L
Sbjct: 204 QAPEDPFVKHCKRFFEFCIPRPILVLLLS-FPSIMVPL 240
>L36085-1|AAC01761.1| 441|Homo sapiens thromboxane A2 synthase
protein.
Length = 441
Score = 66.1 bits (154), Expect = 1e-10
Identities = 58/218 (26%), Positives = 92/218 (42%)
Frame = +2
Query: 2 WSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSFLGDVMQKLCQQFPDRPYFGSFYGTE 181
+ST F ++ + + KP PF GN + Q F M+ L + + P G + G
Sbjct: 32 YSTSAFSRLEKLGLRHPKPSPFIGNLTFF--RQGFWESQME-LRKLY--GPLCGYYLGRR 86
Query: 182 PALVLQNPEIIKQVFTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQNLTPLFS 361
+V+ P++IKQV ++F F +R K V ++ F RW+ +R L FS
Sbjct: 87 MFIVISEPDMIKQVLVENFSNFTNRMASGLEFKSV-ADSVLFLRDKRWEEVRGALMSAFS 145
Query: 362 SSKMKNMFYLVEKCNHSLEDMLDKETKDLQSIEIRSAMIRYTLDSICSSAFGIETNTLSE 541
K+ M L+ + L L + + + +I+ YT D + S FG T S
Sbjct: 146 PEKVNEMVPLISQACDLLLAHLKRYAESGDAFDIQRCYCNYTTDVVASVRFG--TPVDSW 203
Query: 542 GAENSPFPSMGSTIFSSSITRGLKLIGRSMWPGIFYKL 655
A PF F I R + ++ S +P I L
Sbjct: 204 QAPEDPFVKHCKRFFEFCIPRPILVLLLS-FPSIMVPL 240
>AF233618-1|AAF99272.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 66.1 bits (154), Expect = 1e-10
Identities = 58/218 (26%), Positives = 92/218 (42%)
Frame = +2
Query: 2 WSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSFLGDVMQKLCQQFPDRPYFGSFYGTE 181
+ST F ++ + + KP PF GN + Q F M+ L + + P G + G
Sbjct: 32 YSTSAFSRLEKLGLRHPKPSPFIGNLTFF--HQGFWESQME-LRKLY--GPLCGYYLGRR 86
Query: 182 PALVLQNPEIIKQVFTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQNLTPLFS 361
+V+ P++IKQV ++F F +R K V ++ F RW+ +R L FS
Sbjct: 87 MFIVISEPDMIKQVLVENFSNFTNRMASGLEFKSV-ADSVLFLRDKRWEEVRGALMSAFS 145
Query: 362 SSKMKNMFYLVEKCNHSLEDMLDKETKDLQSIEIRSAMIRYTLDSICSSAFGIETNTLSE 541
K+ M L+ + L L + + + +I+ YT D + S FG T S
Sbjct: 146 PEKLNEMVPLISQACDLLLAHLKRYAESGDAFDIQRCYCNYTTDVVASVPFG--TPVDSW 203
Query: 542 GAENSPFPSMGSTIFSSSITRGLKLIGRSMWPGIFYKL 655
A PF F I R + ++ S +P I L
Sbjct: 204 QAPEDPFVKHCKRFFEFCIPRPILVLLLS-FPSIMVPL 240
>AJ563376-2|CAD91645.1| 430|Homo sapiens cytochrome P450 protein.
Length = 430
Score = 62.5 bits (145), Expect = 1e-09
Identities = 35/126 (27%), Positives = 66/126 (52%), Gaps = 2/126 (1%)
Frame = +2
Query: 167 FY-GTEPALVLQNPEIIKQVFTKDFY-YFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQ 340
FY G +P L + +P++IK V K+ Y F +R R + + A + WK +R
Sbjct: 1 FYDGQQPVLAITDPDMIKTVLVKECYSVFTNR--RPFGPVGFMKSAISIAEDEEWKRLRS 58
Query: 341 NLTPLFSSSKMKNMFYLVEKCNHSLEDMLDKETKDLQSIEIRSAMIRYTLDSICSSAFGI 520
L+P F+S K+K M ++ + L L +E + + + ++ Y++D I S++FG+
Sbjct: 59 LLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGV 118
Query: 521 ETNTLS 538
++L+
Sbjct: 119 NIDSLN 124
>AC004914-2|AAP21887.1| 311|Homo sapiens unknown protein.
Length = 311
Score = 61.3 bits (142), Expect = 3e-09
Identities = 46/168 (27%), Positives = 71/168 (42%)
Frame = +2
Query: 152 PYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKV 331
P G + G +V+ P++IKQV ++F F +R K V ++ F RW+
Sbjct: 9 PLCGYYLGRRMFIVISEPDMIKQVLVENFSNFTNRMASGLEFKSV-ADSVLFLRDKRWEE 67
Query: 332 IRQNLTPLFSSSKMKNMFYLVEKCNHSLEDMLDKETKDLQSIEIRSAMIRYTLDSICSSA 511
+R L FS K+ M L+ + L L + + + +I+ YT D + S A
Sbjct: 68 VRGALMSAFSPEKLNEMVPLISQACELLLAHLKRYAESGDAFDIQRCYCNYTTDVVASVA 127
Query: 512 FGIETNTLSEGAENSPFPSMGSTIFSSSITRGLKLIGRSMWPGIFYKL 655
FG T S A PF F I R + ++ S +P I L
Sbjct: 128 FG--TPVDSWQAPEDPFVKHCKRFFEFCIPRPILVLLLS-FPSIMVPL 172
>BC014117-1|AAH14117.1| 466|Homo sapiens TBXAS1 protein protein.
Length = 466
Score = 60.9 bits (141), Expect = 4e-09
Identities = 46/168 (27%), Positives = 71/168 (42%)
Frame = +2
Query: 152 PYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKV 331
P G + G +V+ P++IKQV ++F F +R K V ++ F RW+
Sbjct: 9 PLCGYYLGRRMFIVISEPDMIKQVLVENFSNFTNRMASGLEFKSV-ADSVLFLRDKRWEE 67
Query: 332 IRQNLTPLFSSSKMKNMFYLVEKCNHSLEDMLDKETKDLQSIEIRSAMIRYTLDSICSSA 511
+R L FS K+ M L+ + L L + + + +I+ YT D + S A
Sbjct: 68 VRGALMSAFSPEKLNEMVPLISQACDLLLAHLKRYAESGDAFDIQRCYCNYTTDVVASVA 127
Query: 512 FGIETNTLSEGAENSPFPSMGSTIFSSSITRGLKLIGRSMWPGIFYKL 655
FG T S A PF F I R + ++ S +P I L
Sbjct: 128 FG--TPVDSWQAPEDPFVKHCKRFFEFCIPRPILVLLLS-FPSIMVPL 172
>Y00498-1|CAA68550.1| 490|Homo sapiens IIC2 protein.
Length = 490
Score = 40.3 bits (90), Expect = 0.007
Identities = 31/115 (26%), Positives = 52/115 (45%), Gaps = 6/115 (5%)
Frame = +2
Query: 29 KRKNVPYAKPVPFFGNYMRYITLQSFLGDVMQKLCQQFPD-----RPYFGSFYGTEPALV 193
+RK P P+P GN ++ DV + +C+ F + P F ++G P +V
Sbjct: 26 RRKLPPGPTPLPIIGNMLQI--------DV-KDICKSFTNFSKVYGPVFTVYFGMNPIVV 76
Query: 194 LQNPEIIKQVFTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQ-NLTPL 355
E +K+ + F+ R N + + + +NG RWK IR+ +LT L
Sbjct: 77 FHGYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNGKRWKEIRRFSLTTL 131
>M21941-1|AAA52160.1| 480|Homo sapiens CYP2C protein.
Length = 480
Score = 40.3 bits (90), Expect = 0.007
Identities = 31/115 (26%), Positives = 52/115 (45%), Gaps = 6/115 (5%)
Frame = +2
Query: 29 KRKNVPYAKPVPFFGNYMRYITLQSFLGDVMQKLCQQFPD-----RPYFGSFYGTEPALV 193
+RK P P+P GN ++ DV + +C+ F + P F ++G P +V
Sbjct: 16 RRKLPPGPTPLPIIGNMLQI--------DV-KDICKSFTNFSKVYGPVFTVYFGMNPIVV 66
Query: 194 LQNPEIIKQVFTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQ-NLTPL 355
E +K+ + F+ R N + + + +NG RWK IR+ +LT L
Sbjct: 67 FHGYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNGKRWKEIRRFSLTTL 121
>M17398-1|AAA35740.1| 393|Homo sapiens protein ( Human cytochrome
P-450 1 mRNA, complete cds, clone Hp1-2. ).
Length = 393
Score = 40.3 bits (90), Expect = 0.007
Identities = 36/141 (25%), Positives = 65/141 (46%), Gaps = 5/141 (3%)
Frame = +2
Query: 29 KRKNVPYAKPVPFFGNYMRYITLQSFLGDVMQKLCQQFPD-----RPYFGSFYGTEPALV 193
+RK P P+P GN ++ DV + +C+ F + P F ++G P +V
Sbjct: 26 RRKLPPGPTPLPIIGNMLQI--------DV-KDICKSFTNFSKVYGPVFTVYFGMNPIVV 76
Query: 194 LQNPEIIKQVFTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQNLTPLFSSSKM 373
E +K+ + F+ R N + + + +NG RWK IR+ FS + +
Sbjct: 77 FHGYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNGKRWKEIRR-----FSLTNL 131
Query: 374 KNMFYLVEKCNHSLEDMLDKE 436
+N F + ++ S+ED + +E
Sbjct: 132 RN-FGMGKR---SIEDRVQEE 148
>M17397-1|AAA35739.1| 490|Homo sapiens protein ( Human cytochrome
P-450 1 functional form mRNA, complete cds. ).
Length = 490
Score = 40.3 bits (90), Expect = 0.007
Identities = 36/141 (25%), Positives = 65/141 (46%), Gaps = 5/141 (3%)
Frame = +2
Query: 29 KRKNVPYAKPVPFFGNYMRYITLQSFLGDVMQKLCQQFPD-----RPYFGSFYGTEPALV 193
+RK P P+P GN ++ DV + +C+ F + P F ++G P +V
Sbjct: 26 RRKLPPGPTPLPIIGNMLQI--------DV-KDICKSFTNFSKVYGPVFTVYFGMNPIVV 76
Query: 194 LQNPEIIKQVFTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQNLTPLFSSSKM 373
E +K+ + F+ R N + + + +NG RWK IR+ FS + +
Sbjct: 77 FHGYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNGKRWKEIRR-----FSLTNL 131
Query: 374 KNMFYLVEKCNHSLEDMLDKE 436
+N F + ++ S+ED + +E
Sbjct: 132 RN-FGMGKR---SIEDRVQEE 148
>AY514490-1|AAR89907.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 8 protein.
Length = 490
Score = 40.3 bits (90), Expect = 0.007
Identities = 31/115 (26%), Positives = 52/115 (45%), Gaps = 6/115 (5%)
Frame = +2
Query: 29 KRKNVPYAKPVPFFGNYMRYITLQSFLGDVMQKLCQQFPD-----RPYFGSFYGTEPALV 193
+RK P P+P GN ++ DV + +C+ F + P F ++G P +V
Sbjct: 26 RRKLPPGPTPLPIIGNMLQI--------DV-KDICKSFTNFSKVYGPVFTVYFGMNPIVV 76
Query: 194 LQNPEIIKQVFTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQ-NLTPL 355
E +K+ + F+ R N + + + +NG RWK IR+ +LT L
Sbjct: 77 FHGYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNGKRWKEIRRFSLTTL 131
>AL359672-5|CAH71307.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 8 protein.
Length = 490
Score = 40.3 bits (90), Expect = 0.007
Identities = 31/115 (26%), Positives = 52/115 (45%), Gaps = 6/115 (5%)
Frame = +2
Query: 29 KRKNVPYAKPVPFFGNYMRYITLQSFLGDVMQKLCQQFPD-----RPYFGSFYGTEPALV 193
+RK P P+P GN ++ DV + +C+ F + P F ++G P +V
Sbjct: 26 RRKLPPGPTPLPIIGNMLQI--------DV-KDICKSFTNFSKVYGPVFTVYFGMNPIVV 76
Query: 194 LQNPEIIKQVFTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQ-NLTPL 355
E +K+ + F+ R N + + + +NG RWK IR+ +LT L
Sbjct: 77 FHGYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNGKRWKEIRRFSLTTL 131
>BC020596-1|AAH20596.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 8 protein.
Length = 490
Score = 39.9 bits (89), Expect = 0.009
Identities = 31/115 (26%), Positives = 52/115 (45%), Gaps = 6/115 (5%)
Frame = +2
Query: 29 KRKNVPYAKPVPFFGNYMRYITLQSFLGDVMQKLCQQFPD-----RPYFGSFYGTEPALV 193
+RK P P+P GN ++ DV + +C+ F + P F ++G P +V
Sbjct: 26 RRKLPPGPTPLPIIGNMLQI--------DV-KDICKSFTNFSKVYGPVFTVYFGMNPIVV 76
Query: 194 LQNPEIIKQVFTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQ-NLTPL 355
E +K+ + F+ R N + + + +NG RWK IR+ +LT L
Sbjct: 77 FHGYESVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNGKRWKEIRRFSLTTL 131
>AF280107-1|AAG32291.1| 106|Homo sapiens cytochrome P450
polypeptide 43 protein.
Length = 106
Score = 39.1 bits (87), Expect = 0.016
Identities = 22/81 (27%), Positives = 41/81 (50%), Gaps = 1/81 (1%)
Frame = +2
Query: 2 WSTRKFDYWKRKNVPYAKPVPFFGNYMRYIT-LQSFLGDVMQKLCQQFPDRPYFGSFYGT 178
+ T +K+ +P P+PF G + Y+ L +F + +K + +G + G
Sbjct: 25 YGTHSHKLFKKLGIPGPTPLPFLGTILFYLRGLWNFDRECNEKYGEM------WGLYEGQ 78
Query: 179 EPALVLQNPEIIKQVFTKDFY 241
+P LV+ +P++IK V K+ Y
Sbjct: 79 QPMLVIMDPDMIKTVLVKECY 99
>M21942-1|AAA52161.1| 462|Homo sapiens CYP2C protein.
Length = 462
Score = 38.7 bits (86), Expect = 0.021
Identities = 37/138 (26%), Positives = 62/138 (44%), Gaps = 8/138 (5%)
Frame = +2
Query: 44 PYAKPVPFFGNYMRYITLQSFLGDVMQKLCQQFPD-----RPYFGSFYGTEPALVLQNPE 208
P P+P GN ++ DV + +C+ F + P F ++G P +V E
Sbjct: 3 PGPTPLPIIGNMLQI--------DV-KDICKSFTNFSKVYGPVFTVYFGMNPIVVFHGYE 53
Query: 209 IIKQVFTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQ-NLTPL--FSSSKMKN 379
+K+ + F+ R N + + + +NG RWK IR+ +LT L F K ++
Sbjct: 54 AVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNGKRWKEIRRFSLTTLRNFGMGK-RS 112
Query: 380 MFYLVEKCNHSLEDMLDK 433
+ V++ H L D L K
Sbjct: 113 IEDRVQEEAHCLVDELRK 130
>M61856-1|AAB59356.1| 490|Homo sapiens cytochrome protein.
Length = 490
Score = 37.1 bits (82), Expect = 0.063
Identities = 19/63 (30%), Positives = 30/63 (47%)
Frame = +2
Query: 152 PYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKV 331
P F ++G +P +VL E +K+ F+ R + K + F+NG RWK
Sbjct: 63 PVFTVYFGLKPIVVLHGYEAVKEALIDHGEEFSGRGSFPVAEKVNKGLGILFSNGKRWKE 122
Query: 332 IRQ 340
IR+
Sbjct: 123 IRR 125
>L16876-1|AAA02630.1| 490|Homo sapiens cytochrome P-4502C18
protein.
Length = 490
Score = 37.1 bits (82), Expect = 0.063
Identities = 19/63 (30%), Positives = 30/63 (47%)
Frame = +2
Query: 152 PYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKV 331
P F ++G +P +VL E +K+ F+ R + K + F+NG RWK
Sbjct: 63 PVFTVYFGLKPIVVLHGYEAVKEALIDHGEEFSGRGSFPVAEKVNKGLGILFSNGKRWKE 122
Query: 332 IRQ 340
IR+
Sbjct: 123 IRR 125
>BC096260-1|AAH96260.1| 431|Homo sapiens CYP2C18 protein protein.
Length = 431
Score = 37.1 bits (82), Expect = 0.063
Identities = 19/63 (30%), Positives = 30/63 (47%)
Frame = +2
Query: 152 PYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKV 331
P F ++G +P +VL E +K+ F+ R + K + F+NG RWK
Sbjct: 63 PVFTVYFGLKPIVVLHGYEAVKEALIDHGEEFSGRGSFPVAEKVNKGLGILFSNGKRWKE 122
Query: 332 IRQ 340
IR+
Sbjct: 123 IRR 125
>BC096259-1|AAH96259.1| 443|Homo sapiens CYP2C18 protein protein.
Length = 443
Score = 37.1 bits (82), Expect = 0.063
Identities = 19/63 (30%), Positives = 30/63 (47%)
Frame = +2
Query: 152 PYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKV 331
P F ++G +P +VL E +K+ F+ R + K + F+NG RWK
Sbjct: 63 PVFTVYFGLKPIVVLHGYEAVKEALIDHGEEFSGRGSFPVAEKVNKGLGILFSNGKRWKE 122
Query: 332 IRQ 340
IR+
Sbjct: 123 IRR 125
>BC096258-1|AAH96258.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 protein.
Length = 490
Score = 37.1 bits (82), Expect = 0.063
Identities = 19/63 (30%), Positives = 30/63 (47%)
Frame = +2
Query: 152 PYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKV 331
P F ++G +P +VL E +K+ F+ R + K + F+NG RWK
Sbjct: 63 PVFTVYFGLKPIVVLHGYEAVKEALIDHGEEFSGRGSFPVAEKVNKGLGILFSNGKRWKE 122
Query: 332 IRQ 340
IR+
Sbjct: 123 IRR 125
>BC096257-1|AAH96257.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 protein.
Length = 490
Score = 37.1 bits (82), Expect = 0.063
Identities = 19/63 (30%), Positives = 30/63 (47%)
Frame = +2
Query: 152 PYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKV 331
P F ++G +P +VL E +K+ F+ R + K + F+NG RWK
Sbjct: 63 PVFTVYFGLKPIVVLHGYEAVKEALIDHGEEFSGRGSFPVAEKVNKGLGILFSNGKRWKE 122
Query: 332 IRQ 340
IR+
Sbjct: 123 IRR 125
>BC069666-1|AAH69666.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 protein.
Length = 490
Score = 37.1 bits (82), Expect = 0.063
Identities = 19/63 (30%), Positives = 30/63 (47%)
Frame = +2
Query: 152 PYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKV 331
P F ++G +P +VL E +K+ F+ R + K + F+NG RWK
Sbjct: 63 PVFTVYFGLKPIVVLHGYEAVKEALIDHGEEFSGRGSFPVAEKVNKGLGILFSNGKRWKE 122
Query: 332 IRQ 340
IR+
Sbjct: 123 IRR 125
>BC016853-1|AAH16853.1| 524|Homo sapiens CYP4F11 protein protein.
Length = 524
Score = 37.1 bits (82), Expect = 0.063
Identities = 30/127 (23%), Positives = 56/127 (44%), Gaps = 2/127 (1%)
Frame = +2
Query: 176 TEPALVLQNPEIIKQVFTKDFYYFNSRENRDYNH-KEVFTQNLFFANGDRWKVIRQNLTP 352
T P L+L +P+II+ + T ++ Y K L + GD+W R+ LTP
Sbjct: 95 TFPLLILCHPDIIRPI-TSASAAVAPKDMIFYGFLKPWLGDGLLLSGGDKWSRHRRMLTP 153
Query: 353 LFSSSKMKNMFYLVEKCNHSLEDMLDK-ETKDLQSIEIRSAMIRYTLDSICSSAFGIETN 529
F + +K + K + + D + ++ +++ + TLDS+ F E+N
Sbjct: 154 AFHFNILKPYMKIFNKSVNIMHDKWQRLASEGSARLDMFEHISLMTLDSLQKCVFSFESN 213
Query: 530 TLSEGAE 550
+ +E
Sbjct: 214 CQEKPSE 220
>AL583836-1|CAH74067.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 protein.
Length = 490
Score = 37.1 bits (82), Expect = 0.063
Identities = 19/63 (30%), Positives = 30/63 (47%)
Frame = +2
Query: 152 PYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKV 331
P F ++G +P +VL E +K+ F+ R + K + F+NG RWK
Sbjct: 63 PVFTVYFGLKPIVVLHGYEAVKEALIDHGEEFSGRGSFPVAEKVNKGLGILFSNGKRWKE 122
Query: 332 IRQ 340
IR+
Sbjct: 123 IRR 125
>AF280107-4|AAG32288.1| 106|Homo sapiens cytochrome P450
polypeptide 5 protein.
Length = 106
Score = 37.1 bits (82), Expect = 0.063
Identities = 22/81 (27%), Positives = 39/81 (48%), Gaps = 1/81 (1%)
Frame = +2
Query: 2 WSTRKFDYWKRKNVPYAKPVPFFGNYMRYIT-LQSFLGDVMQKLCQQFPDRPYFGSFYGT 178
+ TR +KR +P P+P GN + Y L F + +K + +G++ G
Sbjct: 25 YGTRTHGLFKRLGIPGPTPLPLLGNVLSYRQGLWKFDTECYKKYGKM------WGTYEGQ 78
Query: 179 EPALVLQNPEIIKQVFTKDFY 241
P L + +P++I+ V K+ Y
Sbjct: 79 LPVLAITDPDVIRTVLVKECY 99
>AF236085-1|AAG15889.1| 524|Homo sapiens CYP4F11 protein.
Length = 524
Score = 37.1 bits (82), Expect = 0.063
Identities = 30/127 (23%), Positives = 56/127 (44%), Gaps = 2/127 (1%)
Frame = +2
Query: 176 TEPALVLQNPEIIKQVFTKDFYYFNSRENRDYNH-KEVFTQNLFFANGDRWKVIRQNLTP 352
T P L+L +P+II+ + T ++ Y K L + GD+W R+ LTP
Sbjct: 95 TFPLLILCHPDIIRPI-TSASAAVAPKDMIFYGFLKPWLGDGLLLSGGDKWSRHRRMLTP 153
Query: 353 LFSSSKMKNMFYLVEKCNHSLEDMLDK-ETKDLQSIEIRSAMIRYTLDSICSSAFGIETN 529
F + +K + K + + D + ++ +++ + TLDS+ F E+N
Sbjct: 154 AFHFNILKPYMKIFNKSVNIMHDKWQRLASEGSARLDMFEHISLMTLDSLQKCVFSFESN 213
Query: 530 TLSEGAE 550
+ +E
Sbjct: 214 CQEKPSE 220
>EF122242-1|ABO41977.1| 321|Homo sapiens cytochrome P450 2F1
variant protein.
Length = 321
Score = 36.7 bits (81), Expect = 0.084
Identities = 42/168 (25%), Positives = 71/168 (42%), Gaps = 5/168 (2%)
Frame = +2
Query: 29 KRKNVPYAKPVPFFGNYMRYITLQSFLGDVMQKLCQQFPDRPYFGSFYGTEPALVLQNPE 208
K K P +P+P GN + + Q L + KL +++ + G +VL +
Sbjct: 27 KGKLPPGPRPLPILGNLL-LLCSQDMLTS-LTKLSKEYGSM--YTVHLGPRRVVVLSGYQ 82
Query: 209 IIKQVFTKDFYYFNSRENRDYNHKEVFTQN--LFFANGDRWKVIRQ---NLTPLFSSSKM 373
+K+ F+ R DY FT+ + F++GDRWKV+RQ + F K
Sbjct: 83 AVKEALVDQGEEFSGRG--DYPAFFNFTKGNGIAFSSGDRWKVLRQFSIQILRNFGMGKR 140
Query: 374 KNMFYLVEKCNHSLEDMLDKETKDLQSIEIRSAMIRYTLDSICSSAFG 517
++E+ + L ++ E + + S R + ICS FG
Sbjct: 141 SIEERILEEGSFLLAELRKTEGEPFDPTFVLS---RSVSNIICSVLFG 185
>X13930-1|CAA32118.1| 494|Homo sapiens protein ( Human CYP2A4 mRNA
for P-450 IIA4 protein. ).
Length = 494
Score = 36.3 bits (80), Expect = 0.11
Identities = 28/113 (24%), Positives = 50/113 (44%)
Frame = +2
Query: 2 WSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSFLGDVMQKLCQQFPDRPYFGSFYGTE 181
W RK K K P P+PF GNY++ T Q + + + K+ +++ P F G
Sbjct: 24 WQQRKS---KGKLPPGPTPLPFIGNYLQLNTEQMY--NSLMKISERY--GPVFTIHLGPR 76
Query: 182 PALVLQNPEIIKQVFTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQ 340
+VL + +++ F+ R + + F+NG+R K +R+
Sbjct: 77 RVVVLCGHDAVREALVDQAEEFSGRGEQATFDWVFKGYGVVFSNGERAKQLRR 129
>M61854-1|AAB59426.1| 490|Homo sapiens cytochrome protein.
Length = 490
Score = 36.3 bits (80), Expect = 0.11
Identities = 37/136 (27%), Positives = 61/136 (44%), Gaps = 1/136 (0%)
Frame = +2
Query: 44 PYAKPVPFFGNYMRYITLQSFLGDVMQKLCQQFPDR-PYFGSFYGTEPALVLQNPEIIKQ 220
P P+P GN LQ + DV + L P F ++G E +VL E++K+
Sbjct: 31 PGPTPLPVIGNI-----LQIDIKDVSKSLTNLSKIYGPVFTLYFGLERMVVLHGYEVVKE 85
Query: 221 VFTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQNLTPLFSSSKMKNMFYLVEK 400
F+ R + + + F+NG RWK IR+ FS ++N F + ++
Sbjct: 86 ALIDLGEEFSGRGHFPLAERANRGFGIVFSNGKRWKEIRR-----FSLMTLRN-FGMGKR 139
Query: 401 CNHSLEDMLDKETKDL 448
S+ED + +E + L
Sbjct: 140 ---SIEDRVQEEARCL 152
>M33318-1|AAA52067.1| 494|Homo sapiens CYP2A protein.
Length = 494
Score = 36.3 bits (80), Expect = 0.11
Identities = 28/113 (24%), Positives = 50/113 (44%)
Frame = +2
Query: 2 WSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSFLGDVMQKLCQQFPDRPYFGSFYGTE 181
W RK K K P P+PF GNY++ T Q + + + K+ +++ P F G
Sbjct: 24 WQQRKS---KGKLPPGPTPLPFIGNYLQLNTEQMY--NSLMKISERY--GPVFTIHLGPR 76
Query: 182 PALVLQNPEIIKQVFTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQ 340
+VL + +++ F+ R + + F+NG+R K +R+
Sbjct: 77 RVVVLCGHDAVREALVDQAEEFSGRGEQATFDWVFKGYGVVFSNGERAKQLRR 129
>L39098-1|AAL31347.1| 160|Homo sapiens S-mephenytoin 4-hydroxylase
protein.
Length = 160
Score = 36.3 bits (80), Expect = 0.11
Identities = 37/136 (27%), Positives = 61/136 (44%), Gaps = 1/136 (0%)
Frame = +2
Query: 44 PYAKPVPFFGNYMRYITLQSFLGDVMQKLCQQFPDR-PYFGSFYGTEPALVLQNPEIIKQ 220
P P+P GN LQ + DV + L P F ++G E +VL E++K+
Sbjct: 31 PGPTPLPVIGNI-----LQIDIKDVSKSLTNLSKIYGPVFTLYFGLERMVVLHGYEVVKE 85
Query: 221 VFTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQNLTPLFSSSKMKNMFYLVEK 400
F+ R + + + F+NG RWK IR+ FS ++N F + ++
Sbjct: 86 ALIDLGEEFSGRGHFPLAERANRGFGIVFSNGKRWKEIRR-----FSLMTLRN-FGMGKR 139
Query: 401 CNHSLEDMLDKETKDL 448
S+ED + +E + L
Sbjct: 140 ---SIEDRVQEEARCL 152
>BC096256-1|AAH96256.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 36.3 bits (80), Expect = 0.11
Identities = 28/113 (24%), Positives = 50/113 (44%)
Frame = +2
Query: 2 WSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSFLGDVMQKLCQQFPDRPYFGSFYGTE 181
W RK K K P P+PF GNY++ T Q + + + K+ +++ P F G
Sbjct: 24 WQQRKS---KGKLPPGPTPLPFIGNYLQLNTEQMY--NSLMKISERY--GPVFTIHLGPR 76
Query: 182 PALVLQNPEIIKQVFTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQ 340
+VL + +++ F+ R + + F+NG+R K +R+
Sbjct: 77 RVVVLCGHDAVREALVDQAEEFSGRGEQATFDWVFKGYGVVFSNGERAKQLRR 129
>BC096255-1|AAH96255.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 36.3 bits (80), Expect = 0.11
Identities = 28/113 (24%), Positives = 50/113 (44%)
Frame = +2
Query: 2 WSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSFLGDVMQKLCQQFPDRPYFGSFYGTE 181
W RK K K P P+PF GNY++ T Q + + + K+ +++ P F G
Sbjct: 24 WQQRKS---KGKLPPGPTPLPFIGNYLQLNTEQMY--NSLMKISERY--GPVFTIHLGPR 76
Query: 182 PALVLQNPEIIKQVFTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQ 340
+VL + +++ F+ R + + F+NG+R K +R+
Sbjct: 77 RVVVLCGHDAVREALVDQAEEFSGRGEQATFDWVFKGYGVVFSNGERAKQLRR 129
>BC096254-1|AAH96254.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 36.3 bits (80), Expect = 0.11
Identities = 28/113 (24%), Positives = 50/113 (44%)
Frame = +2
Query: 2 WSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSFLGDVMQKLCQQFPDRPYFGSFYGTE 181
W RK K K P P+PF GNY++ T Q + + + K+ +++ P F G
Sbjct: 24 WQQRKS---KGKLPPGPTPLPFIGNYLQLNTEQMY--NSLMKISERY--GPVFTIHLGPR 76
Query: 182 PALVLQNPEIIKQVFTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQ 340
+VL + +++ F+ R + + F+NG+R K +R+
Sbjct: 77 RVVVLCGHDAVREALVDQAEEFSGRGEQATFDWVFKGYGVVFSNGERAKQLRR 129
>BC096253-1|AAH96253.3| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 36.3 bits (80), Expect = 0.11
Identities = 28/113 (24%), Positives = 50/113 (44%)
Frame = +2
Query: 2 WSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSFLGDVMQKLCQQFPDRPYFGSFYGTE 181
W RK K K P P+PF GNY++ T Q + + + K+ +++ P F G
Sbjct: 24 WQQRKS---KGKLPPGPTPLPFIGNYLQLNTEQMY--NSLMKISERY--GPVFTIHLGPR 76
Query: 182 PALVLQNPEIIKQVFTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQ 340
+VL + +++ F+ R + + F+NG+R K +R+
Sbjct: 77 RVVVLCGHDAVREALVDQAEEFSGRGEQATFDWVFKGYGVVFSNGERAKQLRR 129
>AY796203-1|AAV41877.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 19 protein.
Length = 490
Score = 36.3 bits (80), Expect = 0.11
Identities = 37/136 (27%), Positives = 61/136 (44%), Gaps = 1/136 (0%)
Frame = +2
Query: 44 PYAKPVPFFGNYMRYITLQSFLGDVMQKLCQQFPDR-PYFGSFYGTEPALVLQNPEIIKQ 220
P P+P GN LQ + DV + L P F ++G E +VL E++K+
Sbjct: 31 PGPTPLPVIGNI-----LQIDIKDVSKSLTNLSKIYGPVFTLYFGLERMVVLHGYEVVKE 85
Query: 221 VFTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQNLTPLFSSSKMKNMFYLVEK 400
F+ R + + + F+NG RWK IR+ FS ++N F + ++
Sbjct: 86 ALIDLGEEFSGRGHFPLAERANRGFGIVFSNGKRWKEIRR-----FSLMTLRN-FGMGKR 139
Query: 401 CNHSLEDMLDKETKDL 448
S+ED + +E + L
Sbjct: 140 ---SIEDRVQEEARCL 152
>AL583836-2|CAH74068.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 19 protein.
Length = 490
Score = 36.3 bits (80), Expect = 0.11
Identities = 37/136 (27%), Positives = 61/136 (44%), Gaps = 1/136 (0%)
Frame = +2
Query: 44 PYAKPVPFFGNYMRYITLQSFLGDVMQKLCQQFPDR-PYFGSFYGTEPALVLQNPEIIKQ 220
P P+P GN LQ + DV + L P F ++G E +VL E++K+
Sbjct: 31 PGPTPLPVIGNI-----LQIDIKDVSKSLTNLSKIYGPVFTLYFGLERMVVLHGYEVVKE 85
Query: 221 VFTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQNLTPLFSSSKMKNMFYLVEK 400
F+ R + + + F+NG RWK IR+ FS ++N F + ++
Sbjct: 86 ALIDLGEEFSGRGHFPLAERANRGFGIVFSNGKRWKEIRR-----FSLMTLRN-FGMGKR 139
Query: 401 CNHSLEDMLDKETKDL 448
S+ED + +E + L
Sbjct: 140 ---SIEDRVQEEARCL 152
>AL133513-2|CAH73444.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 19 protein.
Length = 490
Score = 36.3 bits (80), Expect = 0.11
Identities = 37/136 (27%), Positives = 61/136 (44%), Gaps = 1/136 (0%)
Frame = +2
Query: 44 PYAKPVPFFGNYMRYITLQSFLGDVMQKLCQQFPDR-PYFGSFYGTEPALVLQNPEIIKQ 220
P P+P GN LQ + DV + L P F ++G E +VL E++K+
Sbjct: 31 PGPTPLPVIGNI-----LQIDIKDVSKSLTNLSKIYGPVFTLYFGLERMVVLHGYEVVKE 85
Query: 221 VFTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQNLTPLFSSSKMKNMFYLVEK 400
F+ R + + + F+NG RWK IR+ FS ++N F + ++
Sbjct: 86 ALIDLGEEFSGRGHFPLAERANRGFGIVFSNGKRWKEIRR-----FSLMTLRN-FGMGKR 139
Query: 401 CNHSLEDMLDKETKDL 448
S+ED + +E + L
Sbjct: 140 ---SIEDRVQEEARCL 152
>AF182275-1|AAF13600.1| 494|Homo sapiens cytochrome P450-2A6
protein.
Length = 494
Score = 36.3 bits (80), Expect = 0.11
Identities = 28/113 (24%), Positives = 50/113 (44%)
Frame = +2
Query: 2 WSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSFLGDVMQKLCQQFPDRPYFGSFYGTE 181
W RK K K P P+PF GNY++ T Q + + + K+ +++ P F G
Sbjct: 24 WQQRKS---KGKLPPGPTPLPFIGNYLQLNTEQMY--NSLMKISERY--GPVFTIHLGPR 76
Query: 182 PALVLQNPEIIKQVFTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQ 340
+VL + +++ F+ R + + F+NG+R K +R+
Sbjct: 77 RVVVLCGHDAVREALVDQAEEFSGRGEQATFDWVFKGYGVVFSNGERAKQLRR 129
>X13897-1|CAA32097.1| 489|Homo sapiens protein ( Human mRNA for
cytochrome P-450IIA. ).
Length = 489
Score = 35.9 bits (79), Expect = 0.15
Identities = 28/113 (24%), Positives = 50/113 (44%)
Frame = +2
Query: 2 WSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSFLGDVMQKLCQQFPDRPYFGSFYGTE 181
W RK K K P P+PF GNY++ T Q + + + K+ +++ P F G
Sbjct: 19 WQQRKN---KGKLPPGPTPLPFIGNYLQLNTEQMY--NSLMKISERY--GPVFTIHLGPR 71
Query: 182 PALVLQNPEIIKQVFTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQ 340
+VL + +++ F+ R + + F+NG+R K +R+
Sbjct: 72 RVVVLCGHDAVREALVDQAEEFSGRGEQATFDWVFKGYGVVFSNGERAKQLRR 124
>M29873-1|AAA52143.1| 377|Homo sapiens CYP2B protein.
Length = 377
Score = 35.5 bits (78), Expect = 0.19
Identities = 28/102 (27%), Positives = 46/102 (45%), Gaps = 3/102 (2%)
Frame = +2
Query: 44 PYAKPVPFFGNYM---RYITLQSFLGDVMQKLCQQFPDRPYFGSFYGTEPALVLQNPEII 214
P +P+P GN + R L+SFL + +++ D F G P ++L E I
Sbjct: 32 PGPRPLPLLGNLLQMDRRGLLKSFL-----RFREKYGD--VFTVHLGPRPVVMLCGVEAI 84
Query: 215 KQVFTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQ 340
++ + F+ R + FANG+RWKV+R+
Sbjct: 85 REALVDNAEAFSGRGKIVIMDPVYQGYGMLFANGNRWKVLRR 126
>L07093-1|AAA36660.1| 468|Homo sapiens cytochrome P450 protein.
Length = 468
Score = 35.5 bits (78), Expect = 0.19
Identities = 33/138 (23%), Positives = 62/138 (44%)
Frame = +2
Query: 35 KNVPYAKPVPFFGNYMRYITLQSFLGDVMQKLCQQFPDRPYFGSFYGTEPALVLQNPEII 214
KN P + + ++R TL+ + + + P F ++G E +VL E++
Sbjct: 3 KNSPTQRCLTLATFWIRVATLRKVTTSCLSQQLSKIYG-PVFTLYFGLERMVVLHGYEVV 61
Query: 215 KQVFTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQNLTPLFSSSKMKNMFYLV 394
K+ F+ R + + + F+NG RWK IR+ FS ++N F +
Sbjct: 62 KEALIDLGEEFSGRGHFPLAERANRGFGIVFSNGKRWKEIRR-----FSLMTLRN-FGMG 115
Query: 395 EKCNHSLEDMLDKETKDL 448
++ S+ED + +E + L
Sbjct: 116 KR---SIEDRVQEEARCL 130
>BC041174-1|AAH41174.1| 377|Homo sapiens CYP2B7P1 protein protein.
Length = 377
Score = 35.5 bits (78), Expect = 0.19
Identities = 28/102 (27%), Positives = 46/102 (45%), Gaps = 3/102 (2%)
Frame = +2
Query: 44 PYAKPVPFFGNYM---RYITLQSFLGDVMQKLCQQFPDRPYFGSFYGTEPALVLQNPEII 214
P +P+P GN + R L+SFL + +++ D F G P ++L E I
Sbjct: 32 PGPRPLPLLGNLLQMDRRGLLKSFL-----RFREKYGD--VFTVHLGPRPVVMLCGVEAI 84
Query: 215 KQVFTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQ 340
++ + F+ R + FANG+RWKV+R+
Sbjct: 85 REALVDNAEAFSGRGKIVIMDPVYQGYGMLFANGNRWKVLRR 126
>AK223510-1|BAD97230.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 variant protein.
Length = 490
Score = 35.5 bits (78), Expect = 0.19
Identities = 19/63 (30%), Positives = 29/63 (46%)
Frame = +2
Query: 152 PYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKV 331
P F ++G +P +VL E +K+ F R + K + F+NG RWK
Sbjct: 63 PVFTVYFGLKPIVVLHGYEAVKEALIDHGEEFFGRGSFPVAEKVNKGLGILFSNGKRWKE 122
Query: 332 IRQ 340
IR+
Sbjct: 123 IRR 125
>U22028-1|AAB40519.1| 494|Homo sapiens cytochrome P450 protein.
Length = 494
Score = 35.1 bits (77), Expect = 0.25
Identities = 28/113 (24%), Positives = 50/113 (44%)
Frame = +2
Query: 2 WSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSFLGDVMQKLCQQFPDRPYFGSFYGTE 181
W RK + K P P+PF GNY++ T Q + + + K+ +++ P F G
Sbjct: 24 WRQRKS---RGKLPPGPTPLPFIGNYLQLNTEQMY--NSLMKISERY--GPVFTIHLGPR 76
Query: 182 PALVLQNPEIIKQVFTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQ 340
+VL + +K+ F+ R + + F+NG+R K +R+
Sbjct: 77 RVVVLCGHDAVKEALVDQAEEFSGRGEQATFDWLFKGYGVAFSNGERAKQLRR 129
>AY513609-1|AAR90940.1| 494|Homo sapiens cytochrome P450 2A13
variant 6 protein.
Length = 494
Score = 35.1 bits (77), Expect = 0.25
Identities = 28/113 (24%), Positives = 50/113 (44%)
Frame = +2
Query: 2 WSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSFLGDVMQKLCQQFPDRPYFGSFYGTE 181
W RK + K P P+PF GNY++ T Q + + + K+ +++ P F G
Sbjct: 24 WRQRKS---RGKLPPGPTPLPFIGNYLQLNTEQMY--NSLMKISERY--GPVFTIHLGPR 76
Query: 182 PALVLQNPEIIKQVFTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQ 340
+VL + +K+ F+ R + + F+NG+R K +R+
Sbjct: 77 RVVVLCGHDAVKEALVDQAEEFSGRGEQATFDWLFKGYGVAFSNGERAKQLRR 129
>AY513608-1|AAR90939.1| 494|Homo sapiens cytochrome P450 2A13
variant 5 protein.
Length = 494
Score = 35.1 bits (77), Expect = 0.25
Identities = 28/113 (24%), Positives = 50/113 (44%)
Frame = +2
Query: 2 WSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSFLGDVMQKLCQQFPDRPYFGSFYGTE 181
W RK + K P P+PF GNY++ T Q + + + K+ +++ P F G
Sbjct: 24 WRQRKS---RGKLPPGPTPLPFIGNYLQLNTEQMY--NSLMKISERY--GPVFTIHLGPR 76
Query: 182 PALVLQNPEIIKQVFTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQ 340
+VL + +K+ F+ R + + F+NG+R K +R+
Sbjct: 77 RVVVLCGHDAVKEALVDQAEEFSGRGEQATFDWLFKGYGVAFSNGERAKQLRR 129
>AY513606-1|AAR90937.1| 494|Homo sapiens cytochrome P450 2A13
variant 3 protein.
Length = 494
Score = 35.1 bits (77), Expect = 0.25
Identities = 28/113 (24%), Positives = 50/113 (44%)
Frame = +2
Query: 2 WSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSFLGDVMQKLCQQFPDRPYFGSFYGTE 181
W RK + K P P+PF GNY++ T Q + + + K+ +++ P F G
Sbjct: 24 WRQRKS---RGKLPPGPTPLPFIGNYLQLNTEQMY--NSLMKISERY--GPVFTIHLGPR 76
Query: 182 PALVLQNPEIIKQVFTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQ 340
+VL + +K+ F+ R + + F+NG+R K +R+
Sbjct: 77 RVVVLCGHDAVKEALVDQAEEFSGRGEQATFDWLFKGYGVAFSNGERAKQLRR 129
>AY513605-1|AAR90936.1| 494|Homo sapiens cytochrome P450 2A13
variant 2 protein.
Length = 494
Score = 35.1 bits (77), Expect = 0.25
Identities = 28/113 (24%), Positives = 50/113 (44%)
Frame = +2
Query: 2 WSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSFLGDVMQKLCQQFPDRPYFGSFYGTE 181
W RK + K P P+PF GNY++ T Q + + + K+ +++ P F G
Sbjct: 24 WRQRKS---RGKLPPGPTPLPFIGNYLQLNTEQMY--NSLMKISERY--GPVFTIHLGPR 76
Query: 182 PALVLQNPEIIKQVFTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQ 340
+VL + +K+ F+ R + + F+NG+R K +R+
Sbjct: 77 RVVVLCGHDAVKEALVDQAEEFSGRGEQATFDWLFKGYGVAFSNGERAKQLRR 129
>AY513604-1|AAR90935.1| 494|Homo sapiens cytochrome P450 2A13
variant 1 protein.
Length = 494
Score = 35.1 bits (77), Expect = 0.25
Identities = 28/113 (24%), Positives = 50/113 (44%)
Frame = +2
Query: 2 WSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSFLGDVMQKLCQQFPDRPYFGSFYGTE 181
W RK + K P P+PF GNY++ T Q + + + K+ +++ P F G
Sbjct: 24 WRQRKS---RGKLPPGPTPLPFIGNYLQLNTEQMY--NSLMKISERY--GPVFTIHLGPR 76
Query: 182 PALVLQNPEIIKQVFTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQ 340
+VL + +K+ F+ R + + F+NG+R K +R+
Sbjct: 77 RVVVLCGHDAVKEALVDQAEEFSGRGEQATFDWLFKGYGVAFSNGERAKQLRR 129
>AF209774-1|AAG35775.1| 494|Homo sapiens cytochrome P450 2A13
protein.
Length = 494
Score = 35.1 bits (77), Expect = 0.25
Identities = 28/113 (24%), Positives = 50/113 (44%)
Frame = +2
Query: 2 WSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSFLGDVMQKLCQQFPDRPYFGSFYGTE 181
W RK + K P P+PF GNY++ T Q + + + K+ +++ P F G
Sbjct: 24 WRQRKS---RGKLPPGPTPLPFIGNYLQLNTEQMY--NSLMKISERY--GPVFTIHLGPR 76
Query: 182 PALVLQNPEIIKQVFTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQ 340
+VL + +K+ F+ R + + F+NG+R K +R+
Sbjct: 77 RVVVLCGHDAVKEALVDQAEEFSGRGEQATFDWLFKGYGVAFSNGERAKQLRR 129
>S63426-1|ABB76283.1| 214|Homo sapiens (S)-mephenytoin hydroxylase
associated cytochrome P450 protein.
Length = 214
Score = 34.7 bits (76), Expect = 0.34
Identities = 18/61 (29%), Positives = 28/61 (45%)
Frame = +2
Query: 152 PYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKV 331
P F ++G +P +VL E +K+ F+ R + K + F+NG RWK
Sbjct: 63 PVFTVYFGLKPIVVLHGYEAVKEALIDHGEEFSGRGSFPVAEKVNKGLGILFSNGKRWKE 122
Query: 332 I 334
I
Sbjct: 123 I 123
>M29874-1|AAA52144.1| 491|Homo sapiens CYP2B protein.
Length = 491
Score = 34.7 bits (76), Expect = 0.34
Identities = 38/163 (23%), Positives = 71/163 (43%), Gaps = 5/163 (3%)
Frame = +2
Query: 44 PYAKPVPFFGNYM---RYITLQSFLGDVMQKLCQQFPDRPYFGSFYGTEPALVLQNPEII 214
P +P+P GN + R L+SFL + +++ D F G P ++L E I
Sbjct: 32 PGPRPLPLLGNLLQMDRRGLLKSFL-----RFREKYGD--VFTVHLGPRPVVMLCGVEAI 84
Query: 215 KQVFTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQ-NLTPLFSSSKMKNMFYL 391
++ F+ R + FANG+RWKV+R+ ++T + K +
Sbjct: 85 REALVDKAEAFSGRGKIAMVDPFFRGYGVIFANGNRWKVLRRFSVTTMRDFGMGKRS--V 142
Query: 392 VEKCNHSLEDMLDKETKDLQSIEIRSAMIR-YTLDSICSSAFG 517
E+ + ++++ K ++ + + + T + ICS FG
Sbjct: 143 EERIQEEAQCLIEELRKSKGALMDPTFLFQSITANIICSIVFG 185
>J02906-1|AAA52156.1| 491|Homo sapiens CYP2F1 protein.
Length = 491
Score = 34.7 bits (76), Expect = 0.34
Identities = 42/168 (25%), Positives = 70/168 (41%), Gaps = 5/168 (2%)
Frame = +2
Query: 29 KRKNVPYAKPVPFFGNYMRYITLQSFLGDVMQKLCQQFPDRPYFGSFYGTEPALVLQNPE 208
K K P +P+ GN + + Q L + KL +++ + G +VL +
Sbjct: 27 KGKLPPGPRPLSILGNLL-LLCSQDMLTS-LTKLSKEYGSM--YTVHLGPRRVVVLSGYQ 82
Query: 209 IIKQVFTKDFYYFNSRENRDYNHKEVFTQN--LFFANGDRWKVIRQ---NLTPLFSSSKM 373
+K+ F+ R DY FT+ + F++GDRWKV+RQ + F K
Sbjct: 83 AVKEALVDQGEEFSGRG--DYPAFFNFTKGNGIAFSSGDRWKVLRQFSIQILRNFGMGKR 140
Query: 374 KNMFYLVEKCNHSLEDMLDKETKDLQSIEIRSAMIRYTLDSICSSAFG 517
++E+ + L D+ E + + S R + ICS FG
Sbjct: 141 SIEERILEEGSFLLADVRKTEGEPFDPTFVLS---RSVSNIICSVLFG 185
>DQ298753-1|ABB84469.1| 491|Homo sapiens cytochrome P450, family 2,
subfamily B, polypeptide 6 protein.
Length = 491
Score = 34.7 bits (76), Expect = 0.34
Identities = 38/163 (23%), Positives = 71/163 (43%), Gaps = 5/163 (3%)
Frame = +2
Query: 44 PYAKPVPFFGNYM---RYITLQSFLGDVMQKLCQQFPDRPYFGSFYGTEPALVLQNPEII 214
P +P+P GN + R L+SFL + +++ D F G P ++L E I
Sbjct: 32 PGPRPLPLLGNLLQMDRRGLLKSFL-----RFREKYGD--VFTVHLGPRPVVMLCGVEAI 84
Query: 215 KQVFTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQ-NLTPLFSSSKMKNMFYL 391
++ F+ R + FANG+RWKV+R+ ++T + K +
Sbjct: 85 REALVDKAEAFSGRGKIAMVDPFFRGYGVIFANGNRWKVLRRFSVTTMRDFGMGKRS--V 142
Query: 392 VEKCNHSLEDMLDKETKDLQSIEIRSAMIR-YTLDSICSSAFG 517
E+ + ++++ K ++ + + + T + ICS FG
Sbjct: 143 EERIQEEAQCLIEELRKSKGALMDPTFLFQSITANIICSIVFG 185
>BC067431-1|AAH67431.1| 491|Homo sapiens cytochrome P450, family 2,
subfamily B, polypeptide 6 protein.
Length = 491
Score = 34.7 bits (76), Expect = 0.34
Identities = 38/163 (23%), Positives = 71/163 (43%), Gaps = 5/163 (3%)
Frame = +2
Query: 44 PYAKPVPFFGNYM---RYITLQSFLGDVMQKLCQQFPDRPYFGSFYGTEPALVLQNPEII 214
P +P+P GN + R L+SFL + +++ D F G P ++L E I
Sbjct: 32 PGPRPLPLLGNLLQMDRRGLLKSFL-----RFREKYGD--VFTVHLGPRPVVMLCGVEAI 84
Query: 215 KQVFTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQ-NLTPLFSSSKMKNMFYL 391
++ F+ R + FANG+RWKV+R+ ++T + K +
Sbjct: 85 REALVDKAEAFSGRGKIAMVDPFFRGYGVIFANGNRWKVLRRFSVTTMRDFGMGKRS--V 142
Query: 392 VEKCNHSLEDMLDKETKDLQSIEIRSAMIR-YTLDSICSSAFG 517
E+ + ++++ K ++ + + + T + ICS FG
Sbjct: 143 EERIQEEAQCLIEELRKSKGALMDPTFLFQSITANIICSIVFG 185
>AF182277-1|AAF13602.1| 491|Homo sapiens cytochrome P450-2B6
protein.
Length = 491
Score = 34.7 bits (76), Expect = 0.34
Identities = 38/163 (23%), Positives = 70/163 (42%), Gaps = 5/163 (3%)
Frame = +2
Query: 44 PYAKPVPFFGNYM---RYITLQSFLGDVMQKLCQQFPDRPYFGSFYGTEPALVLQNPEII 214
P +P+P GN + R L+SFL + +++ D F G P ++L E I
Sbjct: 32 PGPRPLPLLGNLLQMDRRGLLKSFL-----RFREKYGD--VFTVHLGPRPVVMLCGVEAI 84
Query: 215 KQVFTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQ-NLTPLFSSSKMKNMFYL 391
++ F+ R + FANG+RWKV+R+ ++T + K +
Sbjct: 85 REALVDKAEAFSGRGKIAMVDPFFRGYGVIFANGNRWKVLRRFSVTTMRDFGMGKRS--V 142
Query: 392 VEKCNHSLEDMLDKETKDLQSIEIRSAMIR-YTLDSICSSAFG 517
E+ + ++++ K ++ + + T + ICS FG
Sbjct: 143 EERTQEEAQCLIEELRKSKGALMDATFLFHSITANIICSIVFG 185
>AC023172-1|AAF32444.1| 491|Homo sapiens CYP2B6 protein.
Length = 491
Score = 34.7 bits (76), Expect = 0.34
Identities = 38/163 (23%), Positives = 71/163 (43%), Gaps = 5/163 (3%)
Frame = +2
Query: 44 PYAKPVPFFGNYM---RYITLQSFLGDVMQKLCQQFPDRPYFGSFYGTEPALVLQNPEII 214
P +P+P GN + R L+SFL + +++ D F G P ++L E I
Sbjct: 32 PGPRPLPLLGNLLQMDRRGLLKSFL-----RFREKYGD--VFTVHLGPRPVVMLCGVEAI 84
Query: 215 KQVFTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQ-NLTPLFSSSKMKNMFYL 391
++ F+ R + FANG+RWKV+R+ ++T + K +
Sbjct: 85 REALVDKAEAFSGRGKIAMVDPFFRGYGVIFANGNRWKVLRRFSVTTMRDFGMGKRS--V 142
Query: 392 VEKCNHSLEDMLDKETKDLQSIEIRSAMIR-YTLDSICSSAFG 517
E+ + ++++ K ++ + + + T + ICS FG
Sbjct: 143 EERIQEEAQCLIEELRKSKGALMDPTFLFQSITANIICSIVFG 185
>BC067430-1|AAH67430.1| 491|Homo sapiens cytochrome P450, family 2,
subfamily B, polypeptide 6 protein.
Length = 491
Score = 34.3 bits (75), Expect = 0.45
Identities = 38/163 (23%), Positives = 70/163 (42%), Gaps = 5/163 (3%)
Frame = +2
Query: 44 PYAKPVPFFGNYM---RYITLQSFLGDVMQKLCQQFPDRPYFGSFYGTEPALVLQNPEII 214
P +P+P GN + R L+SFL + +++ D F G P ++L E I
Sbjct: 32 PGPRPLPLLGNLLQMDRRGLLKSFL-----RFREKYGD--VFTVHLGPRPVVMLCGVEAI 84
Query: 215 KQVFTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQ-NLTPLFSSSKMKNMFYL 391
++ F+ R + FANG+RWKV+R+ ++T + K +
Sbjct: 85 REALVDKAEAFSGRGKIAMVDPFFRGYGVIFANGNRWKVLRRFSVTTMRDFGMGKRS--V 142
Query: 392 VEKCNHSLEDMLDKETKDLQSIEIRSAMIR-YTLDSICSSAFG 517
E+ + ++++ K ++ + + T + ICS FG
Sbjct: 143 EERIQEEAQCLIEELRKSKGALMDPTFLFHSITANIICSIVFG 185
>U22027-1|AAB40518.1| 494|Homo sapiens cytochrome P450 protein.
Length = 494
Score = 33.9 bits (74), Expect = 0.59
Identities = 27/109 (24%), Positives = 47/109 (43%)
Frame = +2
Query: 2 WSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSFLGDVMQKLCQQFPDRPYFGSFYGTE 181
W RK K K P P+PF GNY++ T Q + + + K+ +++ P F G
Sbjct: 24 WQQRKS---KGKLPPGPTPLPFIGNYLQLNTEQMY--NSLMKISERY--GPVFTIHLGPR 76
Query: 182 PALVLQNPEIIKQVFTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWK 328
+VL + +++ F+ R + + F+NG+R K
Sbjct: 77 RVVVLCGHDAVREALVDQAEEFSGRGEQATFDWVFKGYGVVFSNGERAK 125
>S46963-1|AAB23864.2| 477|Homo sapiens cytochrome P-450 protein.
Length = 477
Score = 33.5 bits (73), Expect = 0.78
Identities = 33/135 (24%), Positives = 63/135 (46%)
Frame = +2
Query: 44 PYAKPVPFFGNYMRYITLQSFLGDVMQKLCQQFPDRPYFGSFYGTEPALVLQNPEIIKQV 223
P P+P GN ++ I ++ + + L + + P F ++G +P +VL E +K+
Sbjct: 18 PGPTPLPVIGNILQ-IGIKD-ISKSLTNLSKVYG--PVFTLYFGLKPIVVLHGYEAVKEA 73
Query: 224 FTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQNLTPLFSSSKMKNMFYLVEKC 403
F+ R + + F+NG +WK IR+ FS ++N F + ++
Sbjct: 74 LIDLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIRR-----FSLMTLRN-FGMGKR- 126
Query: 404 NHSLEDMLDKETKDL 448
S+ED + +E + L
Sbjct: 127 --SIEDRVQEEARCL 139
>M21939-1|AAA52158.1| 485|Homo sapiens CYP2C protein.
Length = 485
Score = 33.5 bits (73), Expect = 0.78
Identities = 33/135 (24%), Positives = 63/135 (46%)
Frame = +2
Query: 44 PYAKPVPFFGNYMRYITLQSFLGDVMQKLCQQFPDRPYFGSFYGTEPALVLQNPEIIKQV 223
P P+P GN ++ I ++ + + L + + P F ++G +P +VL E +K+
Sbjct: 26 PGPTPLPVIGNILQ-IGIKD-ISKSLTNLSKVYG--PVFTLYFGLKPIVVLHGYEAVKEA 81
Query: 224 FTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQNLTPLFSSSKMKNMFYLVEKC 403
F+ R + + F+NG +WK IR+ FS ++N F + ++
Sbjct: 82 LIDLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIRR-----FSLMTLRN-FGMGKR- 134
Query: 404 NHSLEDMLDKETKDL 448
S+ED + +E + L
Sbjct: 135 --SIEDRVQEEARCL 147
>M15331-1|AAA52157.1| 485|Homo sapiens CYP2C protein.
Length = 485
Score = 33.5 bits (73), Expect = 0.78
Identities = 33/135 (24%), Positives = 63/135 (46%)
Frame = +2
Query: 44 PYAKPVPFFGNYMRYITLQSFLGDVMQKLCQQFPDRPYFGSFYGTEPALVLQNPEIIKQV 223
P P+P GN ++ I ++ + + L + + P F ++G +P +VL E +K+
Sbjct: 26 PGPTPLPVIGNILQ-IGIKD-ISKSLTNLSKVYG--PVFTLYFGLKPIVVLHGYEAVKEA 81
Query: 224 FTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQNLTPLFSSSKMKNMFYLVEKC 403
F+ R + + F+NG +WK IR+ FS ++N F + ++
Sbjct: 82 LIDLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIRR-----FSLMTLRN-FGMGKR- 134
Query: 404 NHSLEDMLDKETKDL 448
S+ED + +E + L
Sbjct: 135 --SIEDRVQEEARCL 147
>L16880-1|AAD13466.1| 273|Homo sapiens cytochrome P-450 2C protein.
Length = 273
Score = 33.5 bits (73), Expect = 0.78
Identities = 33/135 (24%), Positives = 63/135 (46%)
Frame = +2
Query: 44 PYAKPVPFFGNYMRYITLQSFLGDVMQKLCQQFPDRPYFGSFYGTEPALVLQNPEIIKQV 223
P P+P GN ++ I ++ + + L + + P F ++G +P +VL E +K+
Sbjct: 31 PGPTPLPVIGNILQ-IGIKD-ISKSLTNLSKVYG--PVFTLYFGLKPIVVLHGYEAVKEA 86
Query: 224 FTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQNLTPLFSSSKMKNMFYLVEKC 403
F+ R + + F+NG +WK IR+ FS ++N F + ++
Sbjct: 87 LIDLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIRR-----FSLMTLRN-FGMGKR- 139
Query: 404 NHSLEDMLDKETKDL 448
S+ED + +E + L
Sbjct: 140 --SIEDRVQEEARCL 152
>EF122241-1|ABO41976.1| 491|Homo sapiens cytochrome P450 2F1
variant protein.
Length = 491
Score = 33.5 bits (73), Expect = 0.78
Identities = 41/168 (24%), Positives = 70/168 (41%), Gaps = 5/168 (2%)
Frame = +2
Query: 29 KRKNVPYAKPVPFFGNYMRYITLQSFLGDVMQKLCQQFPDRPYFGSFYGTEPALVLQNPE 208
K K P +P+ GN + + Q L + KL +++ + G +VL +
Sbjct: 27 KGKLPPGPRPLSILGNLL-LLCSQDMLTS-LTKLSKEYGSM--YTVHLGPRRVVVLSGYQ 82
Query: 209 IIKQVFTKDFYYFNSRENRDYNHKEVFTQN--LFFANGDRWKVIRQ---NLTPLFSSSKM 373
+K+ F+ R DY FT+ + F++GDRWKV+RQ + F K
Sbjct: 83 AVKEALVDQGEEFSGRG--DYPAFFNFTKGNGIAFSSGDRWKVLRQFSIQILRNFGMGKR 140
Query: 374 KNMFYLVEKCNHSLEDMLDKETKDLQSIEIRSAMIRYTLDSICSSAFG 517
++E+ + L ++ E + + S R + ICS FG
Sbjct: 141 SIEERILEEGSFLLAELRKTEGEPFDPTFVLS---RSVSNIICSVLFG 185
>D00173-1|BAA00123.1| 487|Homo sapiens cytochrome P-450 protein.
Length = 487
Score = 33.5 bits (73), Expect = 0.78
Identities = 33/135 (24%), Positives = 63/135 (46%)
Frame = +2
Query: 44 PYAKPVPFFGNYMRYITLQSFLGDVMQKLCQQFPDRPYFGSFYGTEPALVLQNPEIIKQV 223
P P+P GN ++ I ++ + + L + + P F ++G +P +VL E +K+
Sbjct: 28 PGPTPLPVIGNILQ-IGIKD-ISKSLTNLSKVYG--PVFTLYFGLKPIVVLHGYEAVKEA 83
Query: 224 FTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQNLTPLFSSSKMKNMFYLVEKC 403
F+ R + + F+NG +WK IR+ FS ++N F + ++
Sbjct: 84 LIDLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIRR-----FSLMTLRN-FGMGKR- 136
Query: 404 NHSLEDMLDKETKDL 448
S+ED + +E + L
Sbjct: 137 --SIEDRVQEEARCL 149
>BC125054-1|AAI25055.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 9 protein.
Length = 490
Score = 33.5 bits (73), Expect = 0.78
Identities = 33/135 (24%), Positives = 63/135 (46%)
Frame = +2
Query: 44 PYAKPVPFFGNYMRYITLQSFLGDVMQKLCQQFPDRPYFGSFYGTEPALVLQNPEIIKQV 223
P P+P GN ++ I ++ + + L + + P F ++G +P +VL E +K+
Sbjct: 31 PGPTPLPVIGNILQ-IGIKD-ISKSLTNLSKVYG--PVFTLYFGLKPIVVLHGYEAVKEA 86
Query: 224 FTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQNLTPLFSSSKMKNMFYLVEKC 403
F+ R + + F+NG +WK IR+ FS ++N F + ++
Sbjct: 87 LIDLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIRR-----FSLMTLRN-FGMGKR- 139
Query: 404 NHSLEDMLDKETKDL 448
S+ED + +E + L
Sbjct: 140 --SIEDRVQEEARCL 152
>BC109056-1|AAI09057.1| 320|Homo sapiens CYP2F1 protein protein.
Length = 320
Score = 33.5 bits (73), Expect = 0.78
Identities = 41/168 (24%), Positives = 70/168 (41%), Gaps = 5/168 (2%)
Frame = +2
Query: 29 KRKNVPYAKPVPFFGNYMRYITLQSFLGDVMQKLCQQFPDRPYFGSFYGTEPALVLQNPE 208
K K P +P+ GN + + Q L + KL +++ + G +VL +
Sbjct: 27 KGKLPPGPRPLSILGNLL-LLCSQDMLTS-LTKLSKEYGSM--YTVHLGPRRVVVLSGYQ 82
Query: 209 IIKQVFTKDFYYFNSRENRDYNHKEVFTQN--LFFANGDRWKVIRQ---NLTPLFSSSKM 373
+K+ F+ R DY FT+ + F++GDRWKV+RQ + F K
Sbjct: 83 AVKEALVDQGEEFSGRG--DYPAFFNFTKGNGIAFSSGDRWKVLRQFSIQILRNFGMGKR 140
Query: 374 KNMFYLVEKCNHSLEDMLDKETKDLQSIEIRSAMIRYTLDSICSSAFG 517
++E+ + L ++ E + + S R + ICS FG
Sbjct: 141 SIEERILEEGSFLLAELRKTEGEPFDPTFVLS---RSVSNIICSVLFG 185
>BC070317-1|AAH70317.1| 162|Homo sapiens CYP2C9 protein protein.
Length = 162
Score = 33.5 bits (73), Expect = 0.78
Identities = 33/135 (24%), Positives = 63/135 (46%)
Frame = +2
Query: 44 PYAKPVPFFGNYMRYITLQSFLGDVMQKLCQQFPDRPYFGSFYGTEPALVLQNPEIIKQV 223
P P+P GN ++ I ++ + + L + + P F ++G +P +VL E +K+
Sbjct: 31 PGPTPLPVIGNILQ-IGIKD-ISKSLTNLSKVYG--PVFTLYFGLKPIVVLHGYEAVKEA 86
Query: 224 FTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQNLTPLFSSSKMKNMFYLVEKC 403
F+ R + + F+NG +WK IR+ FS ++N F + ++
Sbjct: 87 LIDLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIRR-----FSLMTLRN-FGMGKR- 139
Query: 404 NHSLEDMLDKETKDL 448
S+ED + +E + L
Sbjct: 140 --SIEDCVQEEARCL 152
>BC020754-1|AAH20754.1| 162|Homo sapiens CYP2C9 protein protein.
Length = 162
Score = 33.5 bits (73), Expect = 0.78
Identities = 33/135 (24%), Positives = 63/135 (46%)
Frame = +2
Query: 44 PYAKPVPFFGNYMRYITLQSFLGDVMQKLCQQFPDRPYFGSFYGTEPALVLQNPEIIKQV 223
P P+P GN ++ I ++ + + L + + P F ++G +P +VL E +K+
Sbjct: 31 PGPTPLPVIGNILQ-IGIKD-ISKSLTNLSKVYG--PVFTLYFGLKPIVVLHGYEAVKEA 86
Query: 224 FTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQNLTPLFSSSKMKNMFYLVEKC 403
F+ R + + F+NG +WK IR+ FS ++N F + ++
Sbjct: 87 LIDLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIRR-----FSLMTLRN-FGMGKR- 139
Query: 404 NHSLEDMLDKETKDL 448
S+ED + +E + L
Sbjct: 140 --SIEDRVQEEARCL 152
>AY702706-1|AAT94065.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 9 protein.
Length = 490
Score = 33.5 bits (73), Expect = 0.78
Identities = 33/135 (24%), Positives = 63/135 (46%)
Frame = +2
Query: 44 PYAKPVPFFGNYMRYITLQSFLGDVMQKLCQQFPDRPYFGSFYGTEPALVLQNPEIIKQV 223
P P+P GN ++ I ++ + + L + + P F ++G +P +VL E +K+
Sbjct: 31 PGPTPLPVIGNILQ-IGIKD-ISKSLTNLSKVYG--PVFTLYFGLKPIVVLHGYEAVKEA 86
Query: 224 FTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQNLTPLFSSSKMKNMFYLVEKC 403
F+ R + + F+NG +WK IR+ FS ++N F + ++
Sbjct: 87 LIDLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIRR-----FSLMTLRN-FGMGKR- 139
Query: 404 NHSLEDMLDKETKDL 448
S+ED + +E + L
Sbjct: 140 --SIEDRVQEEARCL 152
>AY341248-1|AAP88931.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 9 protein.
Length = 490
Score = 33.5 bits (73), Expect = 0.78
Identities = 33/135 (24%), Positives = 63/135 (46%)
Frame = +2
Query: 44 PYAKPVPFFGNYMRYITLQSFLGDVMQKLCQQFPDRPYFGSFYGTEPALVLQNPEIIKQV 223
P P+P GN ++ I ++ + + L + + P F ++G +P +VL E +K+
Sbjct: 31 PGPTPLPVIGNILQ-IGIKD-ISKSLTNLSKVYG--PVFTLYFGLKPIVVLHGYEAVKEA 86
Query: 224 FTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQNLTPLFSSSKMKNMFYLVEKC 403
F+ R + + F+NG +WK IR+ FS ++N F + ++
Sbjct: 87 LIDLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIRR-----FSLMTLRN-FGMGKR- 139
Query: 404 NHSLEDMLDKETKDL 448
S+ED + +E + L
Sbjct: 140 --SIEDRVQEEARCL 152
>AL359672-1|CAH71303.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 9 protein.
Length = 490
Score = 33.5 bits (73), Expect = 0.78
Identities = 33/135 (24%), Positives = 63/135 (46%)
Frame = +2
Query: 44 PYAKPVPFFGNYMRYITLQSFLGDVMQKLCQQFPDRPYFGSFYGTEPALVLQNPEIIKQV 223
P P+P GN ++ I ++ + + L + + P F ++G +P +VL E +K+
Sbjct: 31 PGPTPLPVIGNILQ-IGIKD-ISKSLTNLSKVYG--PVFTLYFGLKPIVVLHGYEAVKEA 86
Query: 224 FTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQNLTPLFSSSKMKNMFYLVEKC 403
F+ R + + F+NG +WK IR+ FS ++N F + ++
Sbjct: 87 LIDLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIRR-----FSLMTLRN-FGMGKR- 139
Query: 404 NHSLEDMLDKETKDL 448
S+ED + +E + L
Sbjct: 140 --SIEDRVQEEARCL 152
>AF372573-1|AAL69652.1| 495|Homo sapiens cytochrome P450 2F1
protein.
Length = 495
Score = 33.5 bits (73), Expect = 0.78
Identities = 41/168 (24%), Positives = 70/168 (41%), Gaps = 5/168 (2%)
Frame = +2
Query: 29 KRKNVPYAKPVPFFGNYMRYITLQSFLGDVMQKLCQQFPDRPYFGSFYGTEPALVLQNPE 208
K K P +P+ GN + + Q L + KL +++ + G +VL +
Sbjct: 27 KGKLPPGPRPLSILGNLL-LLCSQDMLTS-LTKLSKEYGSM--YTVHLGPRRVVVLSGYQ 82
Query: 209 IIKQVFTKDFYYFNSRENRDYNHKEVFTQN--LFFANGDRWKVIRQ---NLTPLFSSSKM 373
+K+ F+ R DY FT+ + F++GDRWKV+RQ + F K
Sbjct: 83 AVKEALVDQGEEFSGRG--DYPAFFNFTKGNGIAFSSGDRWKVLRQFSIQILRNFGMGKR 140
Query: 374 KNMFYLVEKCNHSLEDMLDKETKDLQSIEIRSAMIRYTLDSICSSAFG 517
++E+ + L ++ E + + S R + ICS FG
Sbjct: 141 SIEERILEEGSFLLAELRKTEGEPFDPTFVLS---RSVSNIICSVLFG 185
>BC033691-1|AAH33691.1| 504|Homo sapiens cytochrome P450, family 2,
subfamily S, polypeptide 1 protein.
Length = 504
Score = 33.1 bits (72), Expect = 1.0
Identities = 23/100 (23%), Positives = 44/100 (44%), Gaps = 1/100 (1%)
Frame = +2
Query: 44 PYAKPVPFFGNYMRYITLQSFLGDVMQKLCQQFPDRPYFGSFYGT-EPALVLQNPEIIKQ 220
P P+P GN ++ + G + +L +++ P F + G P +VL E +++
Sbjct: 34 PGPTPLPLLGNLLQLRPGALYSG--LMRLSKKYG--PVFTIYLGPWRPVVVLVGQEAVRE 89
Query: 221 VFTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQ 340
F+ R +FF+NG+RW+ +R+
Sbjct: 90 ALGGQAEEFSGRGTVAMLEGTFDGHGVFFSNGERWRQLRK 129
>BC028102-1|AAH28102.1| 509|Homo sapiens cytochrome P450, family 4,
subfamily X, polypeptide 1 protein.
Length = 509
Score = 33.1 bits (72), Expect = 1.0
Identities = 27/78 (34%), Positives = 40/78 (51%), Gaps = 5/78 (6%)
Frame = +2
Query: 311 NGDRWKVIRQNLTPLFSSSKMKNMFYLVEKCNHSLEDMLDK-----ETKDLQSIEIRSAM 475
+G +W R+ LTP F + +K +E HS++ MLDK T+D S+E+ +
Sbjct: 129 DGPKWFQHRRLLTPGFHFNILKAY---IEVMAHSVKMMLDKWEKICSTQDT-SVEVYEHI 184
Query: 476 IRYTLDSICSSAFGIETN 529
+LD I AF ETN
Sbjct: 185 NSMSLDIIMKCAFSKETN 202
>AY358603-1|AAQ88966.1| 504|Homo sapiens Cytochrome p450 protein.
Length = 504
Score = 33.1 bits (72), Expect = 1.0
Identities = 23/100 (23%), Positives = 44/100 (44%), Gaps = 1/100 (1%)
Frame = +2
Query: 44 PYAKPVPFFGNYMRYITLQSFLGDVMQKLCQQFPDRPYFGSFYGT-EPALVLQNPEIIKQ 220
P P+P GN ++ + G + +L +++ P F + G P +VL E +++
Sbjct: 34 PGPTPLPLLGNLLQLRPGALYSG--LMRLSKKYG--PVFTIYLGPWRPVVVLVGQEAVRE 89
Query: 221 VFTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQ 340
F+ R +FF+NG+RW+ +R+
Sbjct: 90 ALGGQAEEFSGRGTVAMLEGTFDGHGVFFSNGERWRQLRK 129
>AY358537-1|AAQ88901.1| 509|Homo sapiens EFSW1929 protein.
Length = 509
Score = 33.1 bits (72), Expect = 1.0
Identities = 27/78 (34%), Positives = 40/78 (51%), Gaps = 5/78 (6%)
Frame = +2
Query: 311 NGDRWKVIRQNLTPLFSSSKMKNMFYLVEKCNHSLEDMLDK-----ETKDLQSIEIRSAM 475
+G +W R+ LTP F + +K +E HS++ MLDK T+D S+E+ +
Sbjct: 129 DGPKWFQHRRLLTPGFHFNILKAY---IEVMAHSVKMMLDKWEKICSTQDT-SVEVYEHI 184
Query: 476 IRYTLDSICSSAFGIETN 529
+LD I AF ETN
Sbjct: 185 NSMSLDIIMKCAFSKETN 202
>AM040940-1|CAJ13826.1| 509|Homo sapiens cytochrome P450 protein.
Length = 509
Score = 33.1 bits (72), Expect = 1.0
Identities = 27/78 (34%), Positives = 40/78 (51%), Gaps = 5/78 (6%)
Frame = +2
Query: 311 NGDRWKVIRQNLTPLFSSSKMKNMFYLVEKCNHSLEDMLDK-----ETKDLQSIEIRSAM 475
+G +W R+ LTP F + +K +E HS++ MLDK T+D S+E+ +
Sbjct: 129 DGPKWFQHRRLLTPGFHFNILKAY---IEVMAHSVKMMLDKWEKICSTQDT-SVEVYEHI 184
Query: 476 IRYTLDSICSSAFGIETN 529
+LD I AF ETN
Sbjct: 185 NSMSLDIIMKCAFSKETN 202
>AL450996-1|CAH71035.1| 509|Homo sapiens cytochrome P450, family 4,
subfamily X, polypeptide 1 protein.
Length = 509
Score = 33.1 bits (72), Expect = 1.0
Identities = 27/78 (34%), Positives = 40/78 (51%), Gaps = 5/78 (6%)
Frame = +2
Query: 311 NGDRWKVIRQNLTPLFSSSKMKNMFYLVEKCNHSLEDMLDK-----ETKDLQSIEIRSAM 475
+G +W R+ LTP F + +K +E HS++ MLDK T+D S+E+ +
Sbjct: 129 DGPKWFQHRRLLTPGFHFNILKAY---IEVMAHSVKMMLDKWEKICSTQDT-SVEVYEHI 184
Query: 476 IRYTLDSICSSAFGIETN 529
+LD I AF ETN
Sbjct: 185 NSMSLDIIMKCAFSKETN 202
>AK098065-1|BAC05226.1| 509|Homo sapiens protein ( Homo sapiens
cDNA FLJ40746 fis, clone TRACH2000359, weakly similar to
CYTOCHROME P450 4A4 (EC 1.14.14.1). ).
Length = 509
Score = 33.1 bits (72), Expect = 1.0
Identities = 27/78 (34%), Positives = 40/78 (51%), Gaps = 5/78 (6%)
Frame = +2
Query: 311 NGDRWKVIRQNLTPLFSSSKMKNMFYLVEKCNHSLEDMLDK-----ETKDLQSIEIRSAM 475
+G +W R+ LTP F + +K +E HS++ MLDK T+D S+E+ +
Sbjct: 129 DGPKWFQHRRLLTPGFHFNILKAY---IEVMAHSVKMMLDKWEKICSTQDT-SVEVYEHI 184
Query: 476 IRYTLDSICSSAFGIETN 529
+LD I AF ETN
Sbjct: 185 NSMSLDIIMKCAFSKETN 202
>AK091806-1|BAC03751.1| 444|Homo sapiens protein ( Homo sapiens
cDNA FLJ34487 fis, clone HLUNG2004273, weakly similar to
CYTOCHROME P450 4A4 (EC 1.14.14.1). ).
Length = 444
Score = 33.1 bits (72), Expect = 1.0
Identities = 27/78 (34%), Positives = 40/78 (51%), Gaps = 5/78 (6%)
Frame = +2
Query: 311 NGDRWKVIRQNLTPLFSSSKMKNMFYLVEKCNHSLEDMLDK-----ETKDLQSIEIRSAM 475
+G +W R+ LTP F + +K +E HS++ MLDK T+D S+E+ +
Sbjct: 64 DGPKWFQHRRLLTPGFHFNILKAY---IEVMAHSVKMMLDKWEKICSTQDT-SVEVYEHI 119
Query: 476 IRYTLDSICSSAFGIETN 529
+LD I AF ETN
Sbjct: 120 NSMSLDIIMKCAFSKETN 137
>AK027605-1|BAB55227.1| 564|Homo sapiens protein ( Homo sapiens
cDNA FLJ14699 fis, clone NT2RP2006571, moderately
similar to CYTOCHROME P450 2G1 (EC 1.14.14.1). ).
Length = 564
Score = 33.1 bits (72), Expect = 1.0
Identities = 23/100 (23%), Positives = 44/100 (44%), Gaps = 1/100 (1%)
Frame = +2
Query: 44 PYAKPVPFFGNYMRYITLQSFLGDVMQKLCQQFPDRPYFGSFYGT-EPALVLQNPEIIKQ 220
P P+P GN ++ + G + +L +++ P F + G P +VL E +++
Sbjct: 34 PGPTPLPLLGNLLQLRPGALYSG--LMRLSKKYG--PVFTIYLGPWRPVVVLVGQEAVRE 89
Query: 221 VFTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQ 340
F+ R +FF+NG+RW+ +R+
Sbjct: 90 ALGGQAEEFSGRGTVAMLEGTFDGHGVFFSNGERWRQLRK 129
>AF335278-1|AAK13498.1| 504|Homo sapiens cytochrome P450 2S1
protein.
Length = 504
Score = 33.1 bits (72), Expect = 1.0
Identities = 23/100 (23%), Positives = 44/100 (44%), Gaps = 1/100 (1%)
Frame = +2
Query: 44 PYAKPVPFFGNYMRYITLQSFLGDVMQKLCQQFPDRPYFGSFYGT-EPALVLQNPEIIKQ 220
P P+P GN ++ + G + +L +++ P F + G P +VL E +++
Sbjct: 34 PGPTPLPLLGNLLQLRPGALYSG--LMRLSKKYG--PVFTIYLGPWRPVVVLVGQEAVRE 89
Query: 221 VFTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWKVIRQ 340
F+ R +FF+NG+RW+ +R+
Sbjct: 90 ALGGQAEEFSGRGTVAMLEGTFDGHGVFFSNGERWRQLRK 129
>BC035350-1|AAH35350.1| 524|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 12 protein.
Length = 524
Score = 31.9 bits (69), Expect = 2.4
Identities = 26/125 (20%), Positives = 54/125 (43%), Gaps = 2/125 (1%)
Frame = +2
Query: 182 PALVLQNPEIIKQVFTKDFYYFNSRENRDYNH-KEVFTQNLFFANGDRWKVIRQNLTPLF 358
P +VL +P+ I+ + T ++N K + + + GD+W R+ LTP F
Sbjct: 97 PFIVLCHPDTIRSI-TNASAAIAPKDNLFIRFLKPWLGEGILLSGGDKWSRHRRMLTPAF 155
Query: 359 SSSKMKNMFYLVEK-CNHSLEDMLDKETKDLQSIEIRSAMIRYTLDSICSSAFGIETNTL 535
+ +K+ + K N L+ ++ +++ + TLDS+ F +++
Sbjct: 156 HFNILKSYITIFNKSANIMLDKWQHLASEGSSCLDMFEHISLMTLDSLQKCIFSFDSHCQ 215
Query: 536 SEGAE 550
+E
Sbjct: 216 ERPSE 220
>AY358977-1|AAQ89336.1| 524|Homo sapiens CYP4F12 protein.
Length = 524
Score = 31.9 bits (69), Expect = 2.4
Identities = 26/125 (20%), Positives = 54/125 (43%), Gaps = 2/125 (1%)
Frame = +2
Query: 182 PALVLQNPEIIKQVFTKDFYYFNSRENRDYNH-KEVFTQNLFFANGDRWKVIRQNLTPLF 358
P +VL +P+ I+ + T ++N K + + + GD+W R+ LTP F
Sbjct: 97 PFIVLCHPDTIRSI-TNASAAIAPKDNLFIRFLKPWLGEGILLSGGDKWSRHRRMLTPAF 155
Query: 359 SSSKMKNMFYLVEK-CNHSLEDMLDKETKDLQSIEIRSAMIRYTLDSICSSAFGIETNTL 535
+ +K+ + K N L+ ++ +++ + TLDS+ F +++
Sbjct: 156 HFNILKSYITIFNKSANIMLDKWQHLASEGSSRLDMFEHISLMTLDSLQKCIFSFDSHCQ 215
Query: 536 SEGAE 550
+E
Sbjct: 216 ERPSE 220
>AY008841-1|AAG33247.1| 524|Homo sapiens cytochrome P450 isoform
4F12 protein.
Length = 524
Score = 31.9 bits (69), Expect = 2.4
Identities = 26/125 (20%), Positives = 54/125 (43%), Gaps = 2/125 (1%)
Frame = +2
Query: 182 PALVLQNPEIIKQVFTKDFYYFNSRENRDYNH-KEVFTQNLFFANGDRWKVIRQNLTPLF 358
P +VL +P+ I+ + T ++N K + + + GD+W R+ LTP F
Sbjct: 97 PFIVLCHPDTIRSI-TNASAAIAPKDNLFIRFLKPWLGEGILLSGGDKWSRHRRMLTPAF 155
Query: 359 SSSKMKNMFYLVEK-CNHSLEDMLDKETKDLQSIEIRSAMIRYTLDSICSSAFGIETNTL 535
+ +K+ + K N L+ ++ +++ + TLDS+ F +++
Sbjct: 156 HFNILKSYITIFNKSANIMLDKWQHLASEGSSRLDMFEHISLMTLDSLQKCIFSFDSHCQ 215
Query: 536 SEGAE 550
+E
Sbjct: 216 ERPSE 220
>AC004523-1|AAC11543.1| 458|Homo sapiens F22329_1 protein.
Length = 458
Score = 31.9 bits (69), Expect = 2.4
Identities = 26/125 (20%), Positives = 54/125 (43%), Gaps = 2/125 (1%)
Frame = +2
Query: 182 PALVLQNPEIIKQVFTKDFYYFNSRENRDYNH-KEVFTQNLFFANGDRWKVIRQNLTPLF 358
P +VL +P+ I+ + T ++N K + + + GD+W R+ LTP F
Sbjct: 31 PFIVLCHPDTIRSI-TNASAAIAPKDNLFIRFLKPWLGEGILLSGGDKWSRHRRMLTPAF 89
Query: 359 SSSKMKNMFYLVEK-CNHSLEDMLDKETKDLQSIEIRSAMIRYTLDSICSSAFGIETNTL 535
+ +K+ + K N L+ ++ +++ + TLDS+ F +++
Sbjct: 90 HFNILKSYITIFNKSANIMLDKWQHLASEGSSCLDMFEHISLMTLDSLQKCIFSFDSHCQ 149
Query: 536 SEGAE 550
+E
Sbjct: 150 ERPSE 154
>AB035131-1|BAB18270.1| 524|Homo sapiens cytochrome P450 protein.
Length = 524
Score = 31.9 bits (69), Expect = 2.4
Identities = 26/125 (20%), Positives = 54/125 (43%), Gaps = 2/125 (1%)
Frame = +2
Query: 182 PALVLQNPEIIKQVFTKDFYYFNSRENRDYNH-KEVFTQNLFFANGDRWKVIRQNLTPLF 358
P +VL +P+ I+ + T ++N K + + + GD+W R+ LTP F
Sbjct: 97 PFIVLCHPDTIRSI-TNASAAIAPKDNLFIRFLKPWLGEGILLSGGDKWSRHRRMLTPAF 155
Query: 359 SSSKMKNMFYLVEK-CNHSLEDMLDKETKDLQSIEIRSAMIRYTLDSICSSAFGIETNTL 535
+ +K+ + K N L+ ++ +++ + TLDS+ F +++
Sbjct: 156 HFNILKSYITIFNKSANIMLDKWQHLASEGSSRLDMFEHISLMTLDSLQKCIFSFDSHCQ 215
Query: 536 SEGAE 550
+E
Sbjct: 216 ERPSE 220
>AB035130-1|BAB18269.1| 524|Homo sapiens cytochrome P450 protein.
Length = 524
Score = 31.9 bits (69), Expect = 2.4
Identities = 26/125 (20%), Positives = 54/125 (43%), Gaps = 2/125 (1%)
Frame = +2
Query: 182 PALVLQNPEIIKQVFTKDFYYFNSRENRDYNH-KEVFTQNLFFANGDRWKVIRQNLTPLF 358
P +VL +P+ I+ + T ++N K + + + GD+W R+ LTP F
Sbjct: 97 PFIVLCHPDTIRSI-TNASAAIAPKDNLFIRFLKPWLGEGILLSGGDKWSRHRRMLTPAF 155
Query: 359 SSSKMKNMFYLVEK-CNHSLEDMLDKETKDLQSIEIRSAMIRYTLDSICSSAFGIETNTL 535
+ +K+ + K N L+ ++ +++ + TLDS+ F +++
Sbjct: 156 HFNILKSYITIFNKSANIMLDKWQHLASEGSSRLDMFEHISLMTLDSLQKCIFSFDSHCQ 215
Query: 536 SEGAE 550
+E
Sbjct: 216 ERPSE 220
>BC060857-1|AAH60857.1| 525|Homo sapiens cytochrome P450, family 4,
subfamily V, polypeptide 2 protein.
Length = 525
Score = 31.5 bits (68), Expect = 3.1
Identities = 27/129 (20%), Positives = 54/129 (41%), Gaps = 1/129 (0%)
Frame = +2
Query: 134 QQFPDRPYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRENRDYNHKEVFTQ-NLFFA 310
+++ P + G P + L N E ++ + T S Y E + L +
Sbjct: 82 EEYRHMPLLKLWVGPVPMVALYNAENVEVILTSSKQIDKSSM---YKFLEPWLGLGLLTS 138
Query: 311 NGDRWKVIRQNLTPLFSSSKMKNMFYLVEKCNHSLEDMLDKETKDLQSIEIRSAMIRYTL 490
G++W+ R+ LTP F + +++ ++ + + L L+K ++ + L
Sbjct: 139 TGNKWRSRRKMLTPTFHFTILEDFLDIMNEQANILVKKLEKHINQ-EAFNCFFYITLCAL 197
Query: 491 DSICSSAFG 517
D IC +A G
Sbjct: 198 DIICETAMG 206
>AY422002-1|AAR31180.1| 525|Homo sapiens cytochrome P450 4V2
protein.
Length = 525
Score = 31.5 bits (68), Expect = 3.1
Identities = 27/129 (20%), Positives = 54/129 (41%), Gaps = 1/129 (0%)
Frame = +2
Query: 134 QQFPDRPYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRENRDYNHKEVFTQ-NLFFA 310
+++ P + G P + L N E ++ + T S Y E + L +
Sbjct: 82 EEYRHMPLLKLWVGPVPMVALYNAENVEVILTSSKQIDKSSM---YKFLEPWLGLGLLTS 138
Query: 311 NGDRWKVIRQNLTPLFSSSKMKNMFYLVEKCNHSLEDMLDKETKDLQSIEIRSAMIRYTL 490
G++W+ R+ LTP F + +++ ++ + + L L+K ++ + L
Sbjct: 139 TGNKWRSRRKMLTPTFHFTILEDFLDIMNEQANILVKKLEKHINQ-EAFNCFFYITLCAL 197
Query: 491 DSICSSAFG 517
D IC +A G
Sbjct: 198 DIICETAMG 206
>AK126473-1|BAC86562.1| 503|Homo sapiens protein ( Homo sapiens
cDNA FLJ44509 fis, clone UTERU3001585, weakly similar
to Cytochrome P450 4c3 (EC 1.14.-.-). ).
Length = 503
Score = 31.5 bits (68), Expect = 3.1
Identities = 27/129 (20%), Positives = 54/129 (41%), Gaps = 1/129 (0%)
Frame = +2
Query: 134 QQFPDRPYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRENRDYNHKEVFTQ-NLFFA 310
+++ P + G P + L N E ++ + T S Y E + L +
Sbjct: 60 EEYRHMPLLKLWVGPVPMVALYNAENVEVILTSSKQIDKSSM---YKFLEPWLGLGLLTS 116
Query: 311 NGDRWKVIRQNLTPLFSSSKMKNMFYLVEKCNHSLEDMLDKETKDLQSIEIRSAMIRYTL 490
G++W+ R+ LTP F + +++ ++ + + L L+K ++ + L
Sbjct: 117 TGNKWRSRRKMLTPTFHFTILEDFLDIMNEQANILVKKLEKHINQ-EAFNCFFYITLCAL 175
Query: 491 DSICSSAFG 517
D IC +A G
Sbjct: 176 DIICETAMG 184
>AK122600-1|BAC85487.1| 525|Homo sapiens protein ( Homo sapiens
cDNA FLJ16007 fis, clone KIDNE2006580, weakly similar
to CYTOCHROME P450 4C1 (EC 1.14.14.1). ).
Length = 525
Score = 31.5 bits (68), Expect = 3.1
Identities = 27/129 (20%), Positives = 54/129 (41%), Gaps = 1/129 (0%)
Frame = +2
Query: 134 QQFPDRPYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRENRDYNHKEVFTQ-NLFFA 310
+++ P + G P + L N E ++ + T S Y E + L +
Sbjct: 82 EEYRHMPLLKLWVGPVPMVALYNAENVEVILTSSKQIDKSSM---YKFLEPWLGLGLLTS 138
Query: 311 NGDRWKVIRQNLTPLFSSSKMKNMFYLVEKCNHSLEDMLDKETKDLQSIEIRSAMIRYTL 490
G++W+ R+ LTP F + +++ ++ + + L L+K ++ + L
Sbjct: 139 TGNKWRSRRKMLTPTFHFTILEDFLDIMNEQANILVKKLEKHINQ-EAFNCFFYITLCAL 197
Query: 491 DSICSSAFG 517
D IC +A G
Sbjct: 198 DIICETAMG 206
>BC117165-1|AAI17166.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 7 protein.
Length = 494
Score = 30.7 bits (66), Expect = 5.5
Identities = 27/109 (24%), Positives = 45/109 (41%)
Frame = +2
Query: 2 WSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSFLGDVMQKLCQQFPDRPYFGSFYGTE 181
W RK + K P P+PF GNY++ T + D + K + + P F G
Sbjct: 24 WQQRKS---RGKLPPGPTPLPFIGNYLQLNT--EHICDSIMKFSECY--GPVFTIHLGPR 76
Query: 182 PALVLQNPEIIKQVFTKDFYYFNSRENRDYNHKEVFTQNLFFANGDRWK 328
A+VL + +++ F+ R + + F+NG+R K
Sbjct: 77 RAVVLCGHDAVREALVDQAEEFSGRGEQATFDWVFKGYGVAFSNGERAK 125
>AY280372-1|AAQ21368.1| 519|Homo sapiens cytochrome P450 4A22
protein.
Length = 519
Score = 30.7 bits (66), Expect = 5.5
Identities = 31/134 (23%), Positives = 57/134 (42%), Gaps = 2/134 (1%)
Frame = +2
Query: 119 MQKLCQQFPDR-PYFGSFYGTEPALVLQNPEIIKQVFTKDFYYFNSRENRDYNHKEVFT- 292
+Q+ + FP PY+ +G + + L +P+ +K + + +S+ + Y +
Sbjct: 75 IQERVKTFPSACPYW--IWGGKVRVQLYDPDYMKVILGRS----DSKSHGSYKFLAPWIG 128
Query: 293 QNLFFANGDRWKVIRQNLTPLFSSSKMKNMFYLVEKCNHSLEDMLDKETKDLQSIEIRSA 472
+L NG W R+ LTP F +K L+ + D ++ +E
Sbjct: 129 YSLLLLNGQTWFQHRRMLTPAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEFFQH 188
Query: 473 MIRYTLDSICSSAF 514
+ TLD+I SAF
Sbjct: 189 VSLMTLDTIMKSAF 202
>U19107-1|AAC13989.1| 507|Homo sapiens ZNF127 protein.
Length = 507
Score = 30.3 bits (65), Expect = 7.3
Identities = 11/22 (50%), Positives = 15/22 (68%)
Frame = -3
Query: 168 NDPKYGLSGNCWHSFCITSPRK 103
ND ++G+ NC HSFCI R+
Sbjct: 325 NDRRFGILSNCNHSFCIRCIRR 346
>BC044639-1|AAH44639.1| 507|Homo sapiens makorin, ring finger
protein, 3 protein.
Length = 507
Score = 30.3 bits (65), Expect = 7.3
Identities = 11/22 (50%), Positives = 15/22 (68%)
Frame = -3
Query: 168 NDPKYGLSGNCWHSFCITSPRK 103
ND ++G+ NC HSFCI R+
Sbjct: 325 NDRRFGILSNCNHSFCIRCIRR 346
>U22029-1|AAB40520.1| 494|Homo sapiens cytochrome P450 protein.
Length = 494
Score = 29.9 bits (64), Expect = 9.6
Identities = 28/110 (25%), Positives = 46/110 (41%), Gaps = 1/110 (0%)
Frame = +2
Query: 2 WSTRKFDYWKRKNVPYAKPVPFFGNYMRYITLQSFLGDVMQKLCQQFPDRPYFGSFYGTE 181
W RK + K P P+PF GNY++ T + D + K + + P F G
Sbjct: 24 WQQRKS---RGKLPPGPTPLPFIGNYLQLNT--EHICDSIMKFSECY--GPVFTIHLGPR 76
Query: 182 PALVLQNPEIIKQVFTKDFYYFNSRENRDYNHKEVFT-QNLFFANGDRWK 328
+VL + +++ F+ R + VF + F+NG+R K
Sbjct: 77 RVVVLCGHDAVREALVDQAEEFSGR-GEQATFEWVFKGYGVAFSNGERAK 125
>AL135960-11|CAI19738.1| 455|Homo sapiens cytochrome P450, family
4, subfamily A, polypeptide 22 protein.
Length = 455
Score = 29.9 bits (64), Expect = 9.6
Identities = 20/72 (27%), Positives = 31/72 (43%)
Frame = +2
Query: 299 LFFANGDRWKVIRQNLTPLFSSSKMKNMFYLVEKCNHSLEDMLDKETKDLQSIEIRSAMI 478
L NG W R+ LTP F + +K L+ + D ++ +E+ +
Sbjct: 131 LLLLNGQTWFQHRRMLTPAFHNDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVS 190
Query: 479 RYTLDSICSSAF 514
TLD+I SAF
Sbjct: 191 LMTLDTIMKSAF 202
>AL135960-10|CAI19736.1| 421|Homo sapiens cytochrome P450, family
4, subfamily A, polypeptide 22 protein.
Length = 421
Score = 29.9 bits (64), Expect = 9.6
Identities = 20/72 (27%), Positives = 31/72 (43%)
Frame = +2
Query: 299 LFFANGDRWKVIRQNLTPLFSSSKMKNMFYLVEKCNHSLEDMLDKETKDLQSIEIRSAMI 478
L NG W R+ LTP F + +K L+ + D ++ +E+ +
Sbjct: 131 LLLLNGQTWFQHRRMLTPAFHNDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVS 190
Query: 479 RYTLDSICSSAF 514
TLD+I SAF
Sbjct: 191 LMTLDTIMKSAF 202
>AL135960-9|CAI19737.1| 519|Homo sapiens cytochrome P450, family 4,
subfamily A, polypeptide 22 protein.
Length = 519
Score = 29.9 bits (64), Expect = 9.6
Identities = 20/72 (27%), Positives = 31/72 (43%)
Frame = +2
Query: 299 LFFANGDRWKVIRQNLTPLFSSSKMKNMFYLVEKCNHSLEDMLDKETKDLQSIEIRSAMI 478
L NG W R+ LTP F + +K L+ + D ++ +E+ +
Sbjct: 131 LLLLNGQTWFQHRRMLTPAFHNDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVS 190
Query: 479 RYTLDSICSSAF 514
TLD+I SAF
Sbjct: 191 LMTLDTIMKSAF 202
>AF208532-1|AAF76722.1| 519|Homo sapiens fatty acid
omega-hydroxylase CYP4A11 protein.
Length = 519
Score = 29.9 bits (64), Expect = 9.6
Identities = 20/72 (27%), Positives = 31/72 (43%)
Frame = +2
Query: 299 LFFANGDRWKVIRQNLTPLFSSSKMKNMFYLVEKCNHSLEDMLDKETKDLQSIEIRSAMI 478
L NG W R+ LTP F + +K L+ + D ++ +E+ +
Sbjct: 131 LLLLNGQTWFQHRRMLTPAFHNDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVS 190
Query: 479 RYTLDSICSSAF 514
TLD+I SAF
Sbjct: 191 LMTLDTIMKSAF 202
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 106,991,509
Number of Sequences: 237096
Number of extensions: 2310766
Number of successful extensions: 6935
Number of sequences better than 10.0: 152
Number of HSP's better than 10.0 without gapping: 6045
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6880
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8455186714
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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