Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P16_F_D05
(739 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q16836 Cluster: Hydroxyacyl-coenzyme A dehydrogenase, m... 215 1e-54
UniRef50_Q4DMG1 Cluster: Short chain 3-hydroxyacyl-coa dehydroge... 179 6e-44
UniRef50_Q4PFL4 Cluster: Putative uncharacterized protein; n=1; ... 175 9e-43
UniRef50_P34439 Cluster: Probable 3-hydroxyacyl-CoA dehydrogenas... 172 7e-42
UniRef50_Q5KBI5 Cluster: Short chain 3-hydroxyacyl-CoA dehydroge... 171 1e-41
UniRef50_Q0YNQ2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec... 159 9e-38
UniRef50_UPI00015BAF7B Cluster: 3-hydroxyacyl-CoA dehydrogenase,... 157 3e-37
UniRef50_O29077 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3; c... 150 4e-35
UniRef50_A1SSP5 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec... 146 4e-34
UniRef50_Q97UK9 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=2; S... 144 2e-33
UniRef50_O30218 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; A... 144 2e-33
UniRef50_P45856 Cluster: Probable 3-hydroxybutyryl-CoA dehydroge... 144 2e-33
UniRef50_Q84T13 Cluster: L-3-hydroxyacyl-CoA dehydrogenase subun... 142 8e-33
UniRef50_Q1AV58 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec... 139 6e-32
UniRef50_O28011 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3; A... 139 6e-32
UniRef50_Q978T2 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=5; A... 138 1e-31
UniRef50_Q891F6 Cluster: 3-hydroxybutyryl-coA dehydrogenase; n=3... 136 5e-31
UniRef50_Q9HKW7 Cluster: Probable 3-hydroxyacyl-CoA dehydrogenas... 136 5e-31
UniRef50_Q5L0D2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=3... 136 7e-31
UniRef50_A6ERZ1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 136 7e-31
UniRef50_Q39NP5 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=5... 135 1e-30
UniRef50_Q11TH9 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 134 2e-30
UniRef50_Q9KBD3 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=8... 134 3e-30
UniRef50_Q67SZ4 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; S... 131 2e-29
UniRef50_Q1QBD7 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec... 130 3e-29
UniRef50_Q4J6T7 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2... 130 3e-29
UniRef50_Q47DJ5 Cluster: Enoyl-CoA hydratase/isomerase:3-hydroxy... 129 6e-29
UniRef50_Q1ISD6 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec... 129 8e-29
UniRef50_A0LSM1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=5... 129 8e-29
UniRef50_P40939 Cluster: Trifunctional enzyme subunit alpha, mit... 128 1e-28
UniRef50_O44608 Cluster: Hydroxy-acyl-coa dehydrogenase protein ... 128 2e-28
UniRef50_Q1IIH2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=5... 127 2e-28
UniRef50_P45364 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 127 2e-28
UniRef50_Q11E57 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 127 3e-28
UniRef50_Q1GGC1 Cluster: 3-hydroxyacyl-CoA dehydrogenase NAD-bin... 126 4e-28
UniRef50_P76083 Cluster: Probable 3-hydroxybutyryl-CoA dehydroge... 126 4e-28
UniRef50_Q8XI27 Cluster: Beta-hydroxybutyryl-CoA dehydrogenase N... 126 7e-28
UniRef50_A2TU34 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=4... 126 7e-28
UniRef50_Q64428 Cluster: Trifunctional enzyme subunit alpha, mit... 126 7e-28
UniRef50_A0RUN1 Cluster: 3-hydroxyacyl-CoA dehydrogenase/enoyl-C... 125 1e-27
UniRef50_Q45223 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=9... 125 1e-27
UniRef50_A3YFA8 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 124 2e-27
UniRef50_A0IJE2 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 124 2e-27
UniRef50_Q5KYB5 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=6... 124 3e-27
UniRef50_A0LPA1 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 123 4e-27
UniRef50_Q9YBW6 Cluster: 3-hydroxyacyl-CoA dehydrogenase/3-hydro... 123 5e-27
UniRef50_Q7VRZ0 Cluster: Probable enoyl-CoA hydratase/3-hydroxya... 122 7e-27
UniRef50_Q6MM12 Cluster: Fatty oxidation complex, alpha subunit;... 122 7e-27
UniRef50_Q5V0V6 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2... 122 9e-27
UniRef50_Q8FX64 Cluster: 3-hydroxyacyl-CoA dehydrogenase family ... 122 1e-26
UniRef50_Q6KYW3 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 122 1e-26
UniRef50_Q8YB80 Cluster: 3-HYDROXYBUTYRYL-COA DEHYDROGENASE; n=3... 121 2e-26
UniRef50_A1IEK7 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 121 2e-26
UniRef50_Q12D24 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec... 120 4e-26
UniRef50_A4YDR4 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 120 4e-26
UniRef50_A7D676 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 119 6e-26
UniRef50_Q5UWD9 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3; c... 119 9e-26
UniRef50_Q13I86 Cluster: 3-hydroxybutyryl-CoA epimerase; n=11; B... 118 1e-25
UniRef50_Q9RUA4 Cluster: Enoyl-CoA hydratase/3,2-trans-enoyl-CoA... 118 2e-25
UniRef50_Q1ATL4 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 118 2e-25
UniRef50_Q12AF3 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 118 2e-25
UniRef50_Q9RZ10 Cluster: 3-hydroxyacyl-CoA dehydrogenase, putati... 118 2e-25
UniRef50_A4ALU9 Cluster: 3-hydroxyacyl-CoA dehydrogenase-like pr... 118 2e-25
UniRef50_Q7WCB1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=4... 117 3e-25
UniRef50_Q2B4D1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2... 117 3e-25
UniRef50_A6CP14 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 117 3e-25
UniRef50_Q5V357 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3; H... 117 3e-25
UniRef50_Q9ADL9 Cluster: Beta-hydroxybutyryl-CoA dehydrogenase; ... 117 3e-25
UniRef50_A5V327 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 117 3e-25
UniRef50_A5V4A1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec... 116 6e-25
UniRef50_A1SPQ6 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=3... 116 6e-25
UniRef50_A0Z5J4 Cluster: Enoyl-CoA hydratase; n=2; unclassified ... 116 6e-25
UniRef50_Q8FUX6 Cluster: 3-hydroxyacyl-CoA dehydrogenase family ... 116 8e-25
UniRef50_Q2W2Y1 Cluster: Glyoxysomal fatty acid beta-oxidation m... 115 1e-24
UniRef50_Q668V1 Cluster: Fatty acid oxidation complex subunit al... 115 1e-24
UniRef50_Q5LVD0 Cluster: Enoyl-CoA hydratase/isomerase/3-hydroxy... 115 1e-24
UniRef50_Q5NW50 Cluster: DitN-like 3-hydroxyacyl-CoA dehydrogena... 114 2e-24
UniRef50_Q47M90 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=5... 114 2e-24
UniRef50_O69856 Cluster: Fatty acid oxidation complex alpha-subu... 114 2e-24
UniRef50_O29815 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; A... 114 2e-24
UniRef50_A5WEP3 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 114 2e-24
UniRef50_A4FGV2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2... 114 2e-24
UniRef50_Q9XA30 Cluster: Putative 3-Hydroxyacyl-CoA dehydrogenas... 113 3e-24
UniRef50_A3ZYI9 Cluster: Fatty oxidation complex, alpha subunit ... 113 4e-24
UniRef50_A1SXV8 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 113 4e-24
UniRef50_UPI0000E4974C Cluster: PREDICTED: hypothetical protein;... 112 7e-24
UniRef50_Q1D1F2 Cluster: Fatty oxidation complex, alpha subunit ... 112 7e-24
UniRef50_Q11E55 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 112 7e-24
UniRef50_Q9HRI4 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=7; c... 112 1e-23
UniRef50_Q397D0 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=3... 111 1e-23
UniRef50_A6GC68 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; P... 111 1e-23
UniRef50_O17761 Cluster: Putative uncharacterized protein ech-8;... 111 1e-23
UniRef50_Q2S2J8 Cluster: Fatty oxidation complex, alpha subunit;... 111 2e-23
UniRef50_Q6V1N6 Cluster: PlmT8; n=1; Streptomyces sp. HK803|Rep:... 111 2e-23
UniRef50_A6X670 Cluster: 3-hydroxyacyl-CoA dehydrogenase NAD-bin... 111 2e-23
UniRef50_Q39TJ4 Cluster: 3-hydroxyacyl-CoA dehydrogenase-like; n... 111 2e-23
UniRef50_A7PEM6 Cluster: Chromosome chr11 scaffold_13, whole gen... 110 3e-23
UniRef50_Q5P039 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3; P... 109 5e-23
UniRef50_A1VP66 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 109 5e-23
UniRef50_Q8W1L6 Cluster: Peroxisomal fatty acid beta-oxidation m... 109 5e-23
UniRef50_Q1Z537 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; P... 109 9e-23
UniRef50_Q1NHB4 Cluster: Fatty oxidation complex, alpha subunit;... 109 9e-23
UniRef50_Q6D2L7 Cluster: Fatty acid oxidation complex subunit al... 109 9e-23
UniRef50_Q2J6P6 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=10; ... 108 1e-22
UniRef50_Q28N18 Cluster: 3-hydroxyacyl-CoA dehydrogenase NAD-bin... 108 2e-22
UniRef50_Q1GNH9 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=7... 107 2e-22
UniRef50_Q11ME9 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 107 3e-22
UniRef50_A4BGI3 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; R... 106 6e-22
UniRef50_A0QZR0 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 105 9e-22
UniRef50_A0HAN1 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 105 9e-22
UniRef50_Q4REL3 Cluster: Chromosome 10 SCAF15123, whole genome s... 105 1e-21
UniRef50_Q0SCS0 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=2; A... 105 1e-21
UniRef50_Q06BB6 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2... 105 1e-21
UniRef50_Q28UL9 Cluster: 3-hydroxyacyl-CoA dehydrogenase NAD-bin... 104 3e-21
UniRef50_A7HHZ4 Cluster: 3-hydroxyacyl-CoA dehydrogenase NAD-bin... 103 3e-21
UniRef50_A5N111 Cluster: Hbd2; n=5; Clostridiales|Rep: Hbd2 - Cl... 103 3e-21
UniRef50_A1FNB9 Cluster: 3-hydroxyacyl-CoA dehydrogenase precurs... 103 3e-21
UniRef50_Q5LKF7 Cluster: Fatty oxidation complex, alpha subunit;... 103 6e-21
UniRef50_A1SQH4 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 103 6e-21
UniRef50_A1IDF2 Cluster: 3-hydroxyacyl-CoA dehydrogenase/enoyl-C... 103 6e-21
UniRef50_A0ISW5 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 103 6e-21
UniRef50_Q9L6L5 Cluster: Fatty acid oxidation complex subunit al... 103 6e-21
UniRef50_A1BCA2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec... 102 1e-20
UniRef50_A1FD08 Cluster: 3-hydroxybutyryl-CoA epimerase; n=13; c... 101 1e-20
UniRef50_Q67L77 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 101 2e-20
UniRef50_A4BL13 Cluster: Fatty oxidation complex, alpha subunit;... 101 2e-20
UniRef50_Q8FRT3 Cluster: Putative 3-hydroxybutyryl-CoA dehydroge... 101 2e-20
UniRef50_Q6N3H7 Cluster: Enoyl-CoA hydratase; n=26; Bacteria|Rep... 101 2e-20
UniRef50_A0J682 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 100 3e-20
UniRef50_A4RUY4 Cluster: Predicted protein; n=5; cellular organi... 100 4e-20
UniRef50_A3QGY2 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 99 6e-20
UniRef50_A0W3T3 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec... 99 6e-20
UniRef50_Q3A7N5 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; P... 100 7e-20
UniRef50_A6WDS7 Cluster: 3-hydroxyacyl-CoA dehydrogenase NAD-bin... 100 7e-20
UniRef50_Q3JZL6 Cluster: 3-hydroxyacyl-CoA dehydrogenase, putati... 99 1e-19
UniRef50_Q8ZAN0 Cluster: Fatty acid oxidation complex subunit al... 99 1e-19
UniRef50_Q1DAC1 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenas... 99 1e-19
UniRef50_Q7WIS8 Cluster: Putative enoyl-CoA isomerase; n=2; Bord... 98 2e-19
UniRef50_Q128W2 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 98 2e-19
UniRef50_Q1LBV6 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 98 2e-19
UniRef50_A5IDB6 Cluster: 3-hydroxyacyl CoA dehydrogenase; n=9; G... 98 2e-19
UniRef50_Q0SJP3 Cluster: Bifunctional 3-hydroxyacyl-CoA dehydrog... 97 3e-19
UniRef50_A1SEZ9 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 97 3e-19
UniRef50_A0K022 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec... 97 3e-19
UniRef50_Q4Q939 Cluster: Trifunctional enzyme alpha subunit, mit... 97 4e-19
UniRef50_Q3IIH0 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=4... 97 5e-19
UniRef50_A0QZQ9 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 97 5e-19
UniRef50_Q11BV6 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 96 7e-19
UniRef50_Q5P5K3 Cluster: Alpha-subunit of fatty acid oxidation c... 95 1e-18
UniRef50_Q3KCL0 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 95 1e-18
UniRef50_A5D5N2 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; P... 95 1e-18
UniRef50_A0JVH8 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 95 1e-18
UniRef50_A3T2M8 Cluster: Enoyl-CoA hydratase/isomerase/3-hydroxy... 95 2e-18
UniRef50_Q24N80 Cluster: Putative uncharacterized protein; n=1; ... 95 2e-18
UniRef50_UPI00006A277A Cluster: UPI00006A277A related cluster; n... 94 3e-18
UniRef50_Q73Q34 Cluster: 3-hydroxyacyl-CoA dehydrogenase, putati... 94 4e-18
UniRef50_Q1YTH7 Cluster: Fatty oxidation complex, alpha subunit;... 94 4e-18
UniRef50_Q2SGR6 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; H... 93 6e-18
UniRef50_Q89SH2 Cluster: Blr2428 protein; n=7; Rhizobiales|Rep: ... 93 9e-18
UniRef50_A3M4C7 Cluster: PaaC; n=1; Acinetobacter baumannii ATCC... 93 9e-18
UniRef50_A1WHE6 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; V... 92 1e-17
UniRef50_A1I839 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 92 1e-17
UniRef50_A0JTB4 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=5; A... 92 1e-17
UniRef50_Q5LVG3 Cluster: Enoyl-CoA hydratase/isomerase/3-hydroxy... 91 3e-17
UniRef50_Q1IMY8 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec... 91 3e-17
UniRef50_Q0SEM1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 91 3e-17
UniRef50_A7INS1 Cluster: 3-hydroxyacyl-CoA dehydrogenase NAD-bin... 90 5e-17
UniRef50_A4WWF6 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 90 5e-17
UniRef50_A3JQP6 Cluster: Acetoacetyl-CoA reductase; n=2; Alphapr... 90 5e-17
UniRef50_Q0SEV8 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=3... 90 6e-17
UniRef50_A0LI43 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 89 8e-17
UniRef50_Q39CK1 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=44; ... 89 1e-16
UniRef50_A3N0P8 Cluster: Putative fatty acid oxidation complex a... 89 1e-16
UniRef50_Q8G825 Cluster: Possible butyryl-CoA dehydrogenase; n=2... 89 1e-16
UniRef50_Q08426 Cluster: Peroxisomal bifunctional enzyme (PBE) (... 89 1e-16
UniRef50_Q83DW6 Cluster: Fatty oxidation complex, alpha subunit;... 88 2e-16
UniRef50_Q0EXX8 Cluster: Fatty oxidation complex, alpha subunit;... 88 2e-16
UniRef50_A6DTH3 Cluster: 3-hydroxyacyl-CoA dehydrogenase, C-term... 88 2e-16
UniRef50_Q988C8 Cluster: 3-hydroxybutyryl-coA dehydrogenase; n=1... 87 3e-16
UniRef50_Q68WH7 Cluster: Putative fatty acid oxidation complex t... 87 3e-16
UniRef50_A6UH30 Cluster: 3-hydroxybutyryl-CoA epimerase; n=2; Si... 87 4e-16
UniRef50_A3TT55 Cluster: Putative fatty acid oxidation complex a... 87 4e-16
UniRef50_A5IPA0 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 87 6e-16
UniRef50_A6FFH1 Cluster: Probable 3-hydroxyacyl-CoA dehydrogenas... 86 7e-16
UniRef50_Q93HI5 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=2; A... 86 1e-15
UniRef50_Q4FL01 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3; B... 86 1e-15
UniRef50_Q0LZ25 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 86 1e-15
UniRef50_A5VHQ1 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 86 1e-15
UniRef50_A0LDJ8 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 85 2e-15
UniRef50_A3U7V8 Cluster: 3-hydroxyacyl-CoA dehydrogenase/enoyl-C... 83 7e-15
UniRef50_Q9HJM0 Cluster: Beta-hydroxybutyryl-CoA dehydrogenase r... 82 1e-14
UniRef50_Q14G85 Cluster: Fusion product of 3-hydroxacyl-CoA dehy... 80 5e-14
UniRef50_A6GBG1 Cluster: 3-hydroxyacyl-CoA dehydrogenase/enoyl-C... 80 5e-14
UniRef50_Q5KVJ3 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=16; ... 79 9e-14
UniRef50_A4FJS5 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 79 9e-14
UniRef50_Q7D836 Cluster: 3-hydroxyacyl-CoA dehydrogenase family ... 79 1e-13
UniRef50_Q0LRY2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec... 79 1e-13
UniRef50_Q092W5 Cluster: 3-hydroxyacyl-CoA dehydrogenase/enoyl-C... 79 1e-13
UniRef50_O29090 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; A... 79 1e-13
UniRef50_Q8FRN7 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenas... 78 2e-13
UniRef50_A3VIL7 Cluster: Enoyl-CoA hydratase/isomerase:3-hydroxy... 78 2e-13
UniRef50_Q46MP3 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=4... 78 3e-13
UniRef50_Q02A28 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 78 3e-13
UniRef50_A1CC71 Cluster: 3-hydroxyacyl-CoA dehydrogenase, putati... 78 3e-13
UniRef50_A7S4Z9 Cluster: Predicted protein; n=1; Nematostella ve... 77 3e-13
UniRef50_Q8PMV7 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=7; X... 77 5e-13
UniRef50_A0GEI2 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 77 5e-13
UniRef50_Q0FMY4 Cluster: Enoyl-CoA hydratase; n=1; Roseovarius s... 77 6e-13
UniRef50_A1IFR8 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 77 6e-13
UniRef50_Q9UX37 Cluster: 3-hydroxyacyl-CoA-dehydrogenase; n=4; S... 77 6e-13
UniRef50_Q0YNJ7 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 76 8e-13
UniRef50_Q0AI36 Cluster: 3-hydroxybutyryl-CoA epimerase; n=3; Ni... 75 1e-12
UniRef50_A3ZZK1 Cluster: 3-hydroxybutyryl-coA dehydrogenase; n=1... 75 2e-12
UniRef50_Q4J0Z7 Cluster: 3-hydroxyacyl-CoA dehydrogenase, C-term... 75 2e-12
UniRef50_Q2SGN8 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; H... 74 4e-12
UniRef50_A5UXI1 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 74 4e-12
UniRef50_Q586V7 Cluster: Enoyl-CoA hydratase/Enoyl-CoA isomerase... 74 4e-12
UniRef50_Q8KUG1 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=8; A... 73 1e-11
UniRef50_A1B712 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 73 1e-11
UniRef50_Q6SEY0 Cluster: 3-hydroxyacyl-CoA dehydrogenase domain ... 72 1e-11
UniRef50_Q0RL76 Cluster: Putative 3-hydroxybutyryl-CoA dehydroge... 72 1e-11
UniRef50_Q11EZ3 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 72 2e-11
UniRef50_Q4Q3S6 Cluster: Enoyl-CoA hydratase/Enoyl-CoA isomerase... 72 2e-11
UniRef50_Q396V2 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=9; B... 71 2e-11
UniRef50_A4SW27 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=7; B... 71 3e-11
UniRef50_Q0FUM2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2... 71 4e-11
UniRef50_Q1INT0 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 70 5e-11
UniRef50_Q89HA7 Cluster: Blr6087 protein; n=6; Proteobacteria|Re... 70 7e-11
UniRef50_Q39D25 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=48; ... 70 7e-11
UniRef50_A7HED1 Cluster: 3-hydroxyacyl-CoA dehydrogenase NAD-bin... 69 1e-10
UniRef50_Q392L7 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=9... 68 3e-10
UniRef50_Q160J3 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenas... 68 3e-10
UniRef50_A5V325 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 68 3e-10
UniRef50_O28262 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=2; A... 68 3e-10
UniRef50_Q7WLK3 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenas... 67 4e-10
UniRef50_A5ULU2 Cluster: 3-hydroxyacyl-CoA dehydrogenase, FadB; ... 67 4e-10
UniRef50_A2QA05 Cluster: Catalytic activity:; n=4; Trichocomacea... 66 6e-10
UniRef50_Q5P5K6 Cluster: Fusion of 3-hydroxyacyl-CoA dehydrogena... 66 8e-10
UniRef50_Q0SA65 Cluster: Possible 3-hydroxybutyryl-CoA dehydroge... 66 1e-09
UniRef50_A0PRD1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase FadB... 66 1e-09
UniRef50_Q1RLR0 Cluster: LOC570274 protein; n=4; Clupeocephala|R... 65 1e-09
UniRef50_Q98LG2 Cluster: Mll1034 protein; n=5; Alphaproteobacter... 64 3e-09
UniRef50_Q0RVG8 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; R... 64 3e-09
UniRef50_Q0FUQ2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2... 64 3e-09
UniRef50_Q97HK2 Cluster: 3-Hydroxyacyl-CoA dehydrogenase; n=1; C... 64 3e-09
UniRef50_Q01UM7 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; S... 64 3e-09
UniRef50_A4SW21 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 64 3e-09
UniRef50_A3A5G7 Cluster: Putative uncharacterized protein; n=1; ... 64 5e-09
UniRef50_Q67QQ5 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenas... 63 6e-09
UniRef50_Q0UZL9 Cluster: Putative uncharacterized protein; n=1; ... 63 6e-09
UniRef50_Q5P607 Cluster: Fusion of 3-hydroxyacyl-CoA dehydrogena... 62 2e-08
UniRef50_Q565U7 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; u... 62 2e-08
UniRef50_A7SBT1 Cluster: Predicted protein; n=2; Nematostella ve... 62 2e-08
UniRef50_UPI0000588BF0 Cluster: PREDICTED: similar to 3-hydroxya... 61 3e-08
UniRef50_Q2S396 Cluster: 3-hydroxyacyl-CoA dehydrogenase, C-term... 61 3e-08
UniRef50_Q0C7S2 Cluster: Putative uncharacterized protein; n=1; ... 60 4e-08
UniRef50_Q876X5 Cluster: Dehydrogenase; n=7; Pezizomycotina|Rep:... 60 6e-08
UniRef50_Q4J598 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD bi... 60 7e-08
UniRef50_Q01V22 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 59 1e-07
UniRef50_A2QXC7 Cluster: Contig An11c0270, complete genome. prec... 59 1e-07
UniRef50_A7T366 Cluster: Predicted protein; n=1; Nematostella ve... 59 1e-07
UniRef50_UPI00006A2DC9 Cluster: UPI00006A2DC9 related cluster; n... 58 2e-07
UniRef50_Q39HR3 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=24; ... 58 2e-07
UniRef50_Q9VXI1 Cluster: CG9914-PA; n=5; Diptera|Rep: CG9914-PA ... 58 2e-07
UniRef50_Q7RZ80 Cluster: Putative uncharacterized protein NCU043... 58 2e-07
UniRef50_UPI000050F939 Cluster: COG1250: 3-hydroxyacyl-CoA dehyd... 58 3e-07
UniRef50_Q9Y2S2 Cluster: Lambda-crystallin homolog; n=30; Coelom... 58 3e-07
UniRef50_A4FKS0 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 57 4e-07
UniRef50_Q7UXV2 Cluster: Fatty oxidation complex alpha subunit; ... 57 5e-07
UniRef50_Q1YHC5 Cluster: Putative 3-hydroxybutyryl-CoA dehydroge... 57 5e-07
UniRef50_Q28KL8 Cluster: 3-hydroxyacyl-CoA dehydrogenase NAD-bin... 55 2e-06
UniRef50_Q5HKI5 Cluster: 3-hydroxyacyl-CoA dehydrogenase family ... 55 2e-06
UniRef50_A0VIX4 Cluster: Putative uncharacterized protein precur... 55 2e-06
UniRef50_Q2CEL4 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2... 54 3e-06
UniRef50_Q1GEJ8 Cluster: 3-hydroxyacyl-CoA dehydrogenase NAD-bin... 51 3e-05
UniRef50_A3STE1 Cluster: Putative hydroxlacyl-CoA dehydrogenase;... 51 3e-05
UniRef50_Q5LTH8 Cluster: 3-hydroxyacyl-CoA dehydrogenase family ... 51 3e-05
UniRef50_Q9AF94 Cluster: 3-hydroxyacyl-CoA-dehydrogenase; n=1; A... 50 5e-05
UniRef50_Q24S90 Cluster: Putative uncharacterized protein; n=1; ... 50 6e-05
UniRef50_Q5WI78 Cluster: NADH peroxidase; n=1; Bacillus clausii ... 49 1e-04
UniRef50_Q39LC4 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; B... 48 2e-04
UniRef50_Q0CYI1 Cluster: Predicted protein; n=1; Aspergillus ter... 48 3e-04
UniRef50_Q88X11 Cluster: NADH peroxidase; n=1; Lactobacillus pla... 47 6e-04
UniRef50_Q895T9 Cluster: NADH oxidase; n=28; Bacteria|Rep: NADH ... 46 7e-04
UniRef50_Q2J5F5 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 46 7e-04
UniRef50_A5N930 Cluster: Dihydrolipoyl dehydrogenase; n=1; Clost... 44 0.005
UniRef50_O28421 Cluster: NADH oxidase; n=4; cellular organisms|R... 44 0.005
UniRef50_Q8EYS5 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=4; L... 43 0.007
UniRef50_A2QCM7 Cluster: Catalytic activity: precursor; n=5; Tri... 43 0.007
UniRef50_Q74DS8 Cluster: Pyridine nucleotide-disulphide oxidored... 43 0.009
UniRef50_A6F6Z9 Cluster: FAD dependent oxidoreductase; n=1; Mori... 41 0.028
UniRef50_Q1JZ87 Cluster: FAD-dependent pyridine nucleotide-disul... 40 0.048
UniRef50_Q8G7C3 Cluster: Glycerol-3-phosphate dehydrogenase [NAD... 40 0.048
UniRef50_Q5FJ98 Cluster: Peroxidase; n=8; Lactobacillales|Rep: P... 40 0.064
UniRef50_A7SF39 Cluster: Predicted protein; n=2; Nematostella ve... 39 0.11
UniRef50_Q8R5Q5 Cluster: NADH:flavin oxidoreductases, Old Yellow... 39 0.15
UniRef50_A6Q2Z6 Cluster: UDP-glucose 6-dehydrogenase; n=3; cellu... 39 0.15
UniRef50_A3PTM7 Cluster: FAD-dependent pyridine nucleotide-disul... 39 0.15
UniRef50_Q9RTT3 Cluster: Oxidoreductase, putative; n=2; Deinococ... 38 0.19
UniRef50_Q8KS25 Cluster: NADH:polysulfide oxidoreductase; n=1; T... 38 0.19
UniRef50_Q1GEH8 Cluster: FAD dependent oxidoreductase; n=31; Bac... 38 0.19
UniRef50_A6EGH0 Cluster: Putative short-chain dehydrogenase; n=1... 38 0.19
UniRef50_A5WH60 Cluster: Rubredoxin; n=1; Psychrobacter sp. PRwf... 38 0.19
UniRef50_Q2NGE1 Cluster: Predicted short chain dehydrogenase; n=... 38 0.19
UniRef50_Q123M7 Cluster: FAD dependent oxidoreductase; n=12; Pro... 38 0.26
UniRef50_A3K5J4 Cluster: Putative fatty acid oxidation complex a... 38 0.26
UniRef50_A2SP72 Cluster: Putative ferredoxin reductase; n=1; Met... 38 0.26
UniRef50_Q2UV13 Cluster: Reductases with broad range of substrat... 38 0.26
UniRef50_Q89R44 Cluster: Oxidoreductase; n=23; Bacteria|Rep: Oxi... 38 0.34
UniRef50_Q8CX61 Cluster: Alanine dehydrogenase; n=312; cellular ... 38 0.34
UniRef50_Q8EMX3 Cluster: Hypothetical conserved protein; n=1; Oc... 37 0.45
UniRef50_Q73M80 Cluster: Dihydrolipoyl dehydrogenase; n=1; Trepo... 37 0.45
UniRef50_Q5LMZ3 Cluster: Ubiquinone biosynthesis hydroxylase, Ub... 37 0.45
UniRef50_Q4MR22 Cluster: Putative uncharacterized protein; n=1; ... 37 0.45
UniRef50_Q21MQ4 Cluster: FAD-dependent pyridine nucleotide-disul... 37 0.45
UniRef50_A3PQM0 Cluster: Alcohol dehydrogenase GroES domain prot... 37 0.45
UniRef50_A0PWM6 Cluster: Short-chain type dehydrogenase/reductas... 37 0.45
UniRef50_A0LAN8 Cluster: FAD dependent oxidoreductase; n=1; Magn... 37 0.45
UniRef50_A0IRH0 Cluster: NADH:flavin oxidoreductase/NADH oxidase... 37 0.45
UniRef50_O29311 Cluster: NADH oxidase; n=1; Archaeoglobus fulgid... 37 0.45
UniRef50_P35596 Cluster: Alpha-glycerophosphate oxidase; n=46; L... 37 0.45
UniRef50_Q08352 Cluster: Alanine dehydrogenase; n=81; Bacteria|R... 37 0.45
UniRef50_Q8R5P6 Cluster: NADH:flavin oxidoreductases, Old Yellow... 37 0.59
UniRef50_Q89PW6 Cluster: Blr3364 protein; n=1; Bradyrhizobium ja... 37 0.59
UniRef50_Q8KRG4 Cluster: NADH oxidase; n=14; Bacteria|Rep: NADH ... 37 0.59
UniRef50_Q1Z541 Cluster: 2-enoate reductase (Two distinct NAD(FA... 37 0.59
UniRef50_Q1YTG2 Cluster: NAD binding site:D-amino acid oxidase; ... 37 0.59
UniRef50_Q1YST5 Cluster: Oxidoreductase, FAD-binding; n=2; cellu... 37 0.59
UniRef50_Q1QEV5 Cluster: FAD dependent oxidoreductase; n=1; Psyc... 37 0.59
UniRef50_Q13FW6 Cluster: Putative FAD dependent oxidoreductase; ... 37 0.59
UniRef50_A6LXK6 Cluster: FAD-dependent pyridine nucleotide-disul... 37 0.59
UniRef50_A4EBM5 Cluster: Putative uncharacterized protein; n=1; ... 37 0.59
UniRef50_A0UVE8 Cluster: Alcohol dehydrogenase GroES-like; n=1; ... 37 0.59
UniRef50_Q8K9T7 Cluster: Dihydrolipoyl dehydrogenase; n=33; Gamm... 37 0.59
UniRef50_Q98RI6 Cluster: NADH OXIDASE; n=9; Mycoplasma|Rep: NADH... 36 0.78
UniRef50_Q67SD1 Cluster: Glycerol-3-phosphate dehydrogenase; n=1... 36 0.78
UniRef50_Q5P4H0 Cluster: Flavorubredoxin reductase [(Nitric oxid... 36 0.78
UniRef50_Q3AKN2 Cluster: Zeta-carotene desaturase-like; n=14; ce... 36 0.78
UniRef50_Q1GKM6 Cluster: Ubiquinone biosynthesis hydroxylase Ubi... 36 0.78
UniRef50_Q1AS94 Cluster: FAD-dependent pyridine nucleotide-disul... 36 0.78
UniRef50_Q0I616 Cluster: NAD binding site:D-amino acid oxidase; ... 36 0.78
UniRef50_Q0FXY7 Cluster: Xanthine dehydrogenase protein; n=3; Al... 36 0.78
UniRef50_A3I2V6 Cluster: Alcohol dehydrogenase, zinc-containing;... 36 0.78
UniRef50_A3LNM6 Cluster: Glycerol-3-phospate dehydrogenase; n=6;... 36 0.78
UniRef50_Q92XP5 Cluster: Opine oxidase subunit B; n=4; Proteobac... 36 0.78
UniRef50_P37062 Cluster: NADH peroxidase; n=4; Lactobacillales|R... 36 0.78
UniRef50_Q98GG6 Cluster: L-iditol 2-dehydrogenase; n=5; Alphapro... 36 1.0
UniRef50_Q890W4 Cluster: Rubredoxin; n=1; Clostridium tetani|Rep... 36 1.0
UniRef50_Q6MR87 Cluster: GlpD protein; n=1; Bdellovibrio bacteri... 36 1.0
UniRef50_Q5FP72 Cluster: Glycerol-3-phosphate dehydrogenase; n=3... 36 1.0
UniRef50_Q2KCX6 Cluster: Probable zinc-type alcohol dehydrogenas... 36 1.0
UniRef50_A6Q6U8 Cluster: K+ transport system, NAD-binding compon... 36 1.0
UniRef50_A6LIY7 Cluster: NADH:flavin oxidoreductase/NADH oxidase... 36 1.0
UniRef50_A5KPS1 Cluster: Putative uncharacterized protein; n=1; ... 36 1.0
UniRef50_A5EBF0 Cluster: Putative uncharacterized protein; n=1; ... 36 1.0
UniRef50_A2EHA4 Cluster: 3-hydroxyacyl-CoA dehydrogenase, putati... 36 1.0
UniRef50_P37061 Cluster: NADH oxidase; n=12; Bacteria|Rep: NADH ... 36 1.0
UniRef50_UPI000023EFE7 Cluster: hypothetical protein FG05678.1; ... 36 1.4
UniRef50_Q1J352 Cluster: UDP-glucose 6-dehydrogenase; n=3; cellu... 36 1.4
UniRef50_Q18RI2 Cluster: 3-hydroxyacyl-CoA dehydrogenase-like; n... 36 1.4
UniRef50_Q123K5 Cluster: FAD dependent oxidoreductase; n=1; Pola... 36 1.4
UniRef50_Q0I6J4 Cluster: Glycine oxidase ThiO; n=19; Cyanobacter... 36 1.4
UniRef50_O85286 Cluster: Initial dioxygenase reductase subunit; ... 36 1.4
UniRef50_A5G7E5 Cluster: NADH:flavin oxidoreductase/NADH oxidase... 36 1.4
UniRef50_A1HU70 Cluster: FAD dependent oxidoreductase; n=1; Ther... 36 1.4
UniRef50_A0YCT0 Cluster: Putative uncharacterized protein; n=1; ... 36 1.4
UniRef50_A0PVI7 Cluster: Short chain dehydrogenase; n=5; Bacteri... 36 1.4
UniRef50_Q7N4V5 Cluster: Similar to 3-phenylpropionate dioxygena... 35 1.8
UniRef50_Q2KZL2 Cluster: Putative ferredoxin reductase; n=1; Bor... 35 1.8
UniRef50_Q21KP6 Cluster: Putative uncharacterized protein; n=1; ... 35 1.8
UniRef50_Q1FMM1 Cluster: Dihydrolipoyl dehydrogenase; n=2; Clost... 35 1.8
UniRef50_A5KQR4 Cluster: Putative uncharacterized protein; n=1; ... 35 1.8
UniRef50_A4XGK6 Cluster: FAD-dependent pyridine nucleotide-disul... 35 1.8
UniRef50_A4F728 Cluster: Amino acid oxidase flavoprotein ThiO, p... 35 1.8
UniRef50_A3IBN0 Cluster: Predicted short chain dehydrogenase; n=... 35 1.8
UniRef50_A0WZQ3 Cluster: FAD dependent oxidoreductase; n=1; Shew... 35 1.8
UniRef50_A1RR43 Cluster: FAD-dependent pyridine nucleotide-disul... 35 1.8
UniRef50_Q8ZMJ6 Cluster: Nitric oxide reductase FlRd-NAD(+) redu... 35 1.8
UniRef50_Q92I05 Cluster: Glycerol-3-phosphate dehydrogenase [NAD... 35 1.8
UniRef50_P61746 Cluster: Glycerol-3-phosphate dehydrogenase [NAD... 35 1.8
UniRef50_Q987J9 Cluster: Sarcosine oxidase, subunit beta; n=2; A... 35 2.4
UniRef50_Q4FUY1 Cluster: Possible pyridine nucleotide-disulphide... 35 2.4
UniRef50_Q2JYT9 Cluster: D-Octopine oxidase, subunit B protein; ... 35 2.4
UniRef50_Q9R689 Cluster: Tiorf193 protein; n=3; Agrobacterium tu... 35 2.4
UniRef50_Q93EX5 Cluster: EthA; n=3; Actinomycetales|Rep: EthA - ... 35 2.4
UniRef50_Q21W02 Cluster: FAD dependent oxidoreductase; n=3; Prot... 35 2.4
UniRef50_Q1IIF5 Cluster: FAD dependent oxidoreductase; n=1; Acid... 35 2.4
UniRef50_Q1EVV0 Cluster: Dihydrolipoyl dehydrogenase; n=6; Clost... 35 2.4
UniRef50_Q189R5 Cluster: Dihydrolipoyl dehydrogenase; n=3; Clost... 35 2.4
UniRef50_Q11D32 Cluster: FAD dependent oxidoreductase; n=5; Rhiz... 35 2.4
UniRef50_Q0SFR2 Cluster: Probable ferredoxin--NAD(+) reductase; ... 35 2.4
UniRef50_A3J8W1 Cluster: 2-octaprenyl-3-methyl-6-methoxy-1,4-ben... 35 2.4
UniRef50_A3DF49 Cluster: Single-stranded-DNA-specific exonucleas... 35 2.4
UniRef50_A0ZZT3 Cluster: Glycerol-3-phosphate dehydrogenase; n=2... 35 2.4
UniRef50_Q54QC1 Cluster: Putative uncharacterized protein; n=1; ... 35 2.4
UniRef50_Q54I29 Cluster: Putative uncharacterized protein; n=1; ... 35 2.4
UniRef50_Q4UBA9 Cluster: Ferrodoxin reductase-like protein, puta... 35 2.4
UniRef50_A6S4B5 Cluster: Putative uncharacterized protein; n=1; ... 35 2.4
UniRef50_A3DNK1 Cluster: Dihydrolipoamide dehydrogenase; n=1; St... 35 2.4
UniRef50_Q9KEC1 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 34 3.2
UniRef50_Q8R5T2 Cluster: NADH:flavin oxidoreductases, Old Yellow... 34 3.2
UniRef50_Q88VV8 Cluster: NADH oxidase; n=1; Lactobacillus planta... 34 3.2
UniRef50_Q81UX6 Cluster: Glycine oxidase; n=10; Bacillus cereus ... 34 3.2
UniRef50_Q7V9G3 Cluster: FAD dependent oxidoreductase; n=2; Proc... 34 3.2
UniRef50_Q6N2W0 Cluster: Possible oxidoreductase; n=11; Bradyrhi... 34 3.2
UniRef50_Q6MDA0 Cluster: Probable soluble pyridine nucleotide tr... 34 3.2
UniRef50_Q4L6L9 Cluster: Dihydrolipoyl dehydrogenase; n=16; Stap... 34 3.2
UniRef50_Q15TU3 Cluster: Methyltransferase type 11; n=1; Pseudoa... 34 3.2
UniRef50_Q0K330 Cluster: Pyridine nucleotide-disulphide oxidored... 34 3.2
UniRef50_Q041G8 Cluster: Acetoin/pyruvate dehydrogenase complex,... 34 3.2
UniRef50_A7HAP4 Cluster: FAD-dependent pyridine nucleotide-disul... 34 3.2
UniRef50_A7B6D3 Cluster: Putative uncharacterized protein; n=1; ... 34 3.2
UniRef50_A6LSH9 Cluster: Phosphate binding protein precursor; n=... 34 3.2
UniRef50_A5TUD7 Cluster: NADH dehydrogenase; n=3; Fusobacterium ... 34 3.2
UniRef50_A5KMT9 Cluster: Putative uncharacterized protein; n=1; ... 34 3.2
UniRef50_A3XHA5 Cluster: Regulatory protein; n=4; Flavobacteriac... 34 3.2
UniRef50_A3VU66 Cluster: Ferredoxin reductase; n=1; Parvularcula... 34 3.2
UniRef50_A3KD01 Cluster: Ferredoxin reductase component of biphe... 34 3.2
UniRef50_A0P1B6 Cluster: Probable oxidoreductase; n=1; Stappia a... 34 3.2
UniRef50_A0LU97 Cluster: Prephenate dehydrogenase; n=1; Acidothe... 34 3.2
UniRef50_A0LQU5 Cluster: FAD dependent oxidoreductase; n=3; Acti... 34 3.2
UniRef50_Q17IV5 Cluster: Chromodomain helicase DNA binding prote... 34 3.2
UniRef50_Q5V4I2 Cluster: Glycerol-3-phosphate dehydrogenase; n=3... 34 3.2
UniRef50_Q8XH94 Cluster: Phage infection protein; n=7; Clostridi... 34 4.2
UniRef50_Q8KB91 Cluster: Protoporphyrinogen oxidase, putative; n... 34 4.2
UniRef50_Q8ELC1 Cluster: Oxidoreductase; n=1; Oceanobacillus ihe... 34 4.2
UniRef50_Q8CQA3 Cluster: Dihydrolipoyl dehydrogenase; n=4; Staph... 34 4.2
UniRef50_Q2GA84 Cluster: Short-chain dehydrogenase/reductase SDR... 34 4.2
UniRef50_O69694 Cluster: POSSIBLE OXIDOREDUCTASE; n=7; Mycobacte... 34 4.2
UniRef50_Q7X2D3 Cluster: D-amino acid oxidase; n=1; Arthrobacter... 34 4.2
UniRef50_Q2HWH5 Cluster: Ferredoxin reductase component of carba... 34 4.2
UniRef50_Q1R1L7 Cluster: Ubiquinone biosynthesis hydroxylase, Ub... 34 4.2
UniRef50_Q1N298 Cluster: Short chain dehydrogenase; n=1; Oceanob... 34 4.2
UniRef50_Q1GVP3 Cluster: Alanine dehydrogenase; n=20; Bacteria|R... 34 4.2
UniRef50_Q1GDR3 Cluster: FAD-dependent pyridine nucleotide-disul... 34 4.2
UniRef50_Q1DFL4 Cluster: Mercuric reductase, truncated; n=1; Myx... 34 4.2
UniRef50_Q18VX2 Cluster: FAD-dependent pyridine nucleotide-disul... 34 4.2
UniRef50_Q143U1 Cluster: Putative redutase; n=1; Burkholderia xe... 34 4.2
UniRef50_Q0VLA2 Cluster: Oxygenase; n=1; Alcanivorax borkumensis... 34 4.2
UniRef50_Q0HM21 Cluster: FAD dependent oxidoreductase; n=17; Alt... 34 4.2
UniRef50_Q01ZR5 Cluster: Short-chain dehydrogenase/reductase SDR... 34 4.2
UniRef50_A7B6H9 Cluster: Putative uncharacterized protein; n=1; ... 34 4.2
UniRef50_A6VYV8 Cluster: NADH:flavin oxidoreductase/NADH oxidase... 34 4.2
UniRef50_A6TTB6 Cluster: TrkA-N domain protein; n=1; Alkaliphilu... 34 4.2
UniRef50_A6GUU8 Cluster: Putative thiol:disulfide interchange pr... 34 4.2
UniRef50_A6EW64 Cluster: FAD dependent oxidoreductase; n=1; Mari... 34 4.2
UniRef50_Q93ZM6 Cluster: AT5g63620/MBK5_9; n=6; Magnoliophyta|Re... 34 4.2
UniRef50_Q2HI16 Cluster: Putative uncharacterized protein; n=1; ... 34 4.2
UniRef50_Q2NHI6 Cluster: Predicted E1-like enzyme; n=1; Methanos... 34 4.2
UniRef50_UPI00004D5C27 Cluster: L-amino-acid oxidase precursor (... 33 5.5
UniRef50_Q9PF43 Cluster: 2-octaprenyl-6-methoxyphenol hydroxylas... 33 5.5
UniRef50_Q8G5A1 Cluster: Adenosylhomocysteinase; n=3; Bifidobact... 33 5.5
UniRef50_Q8EQH1 Cluster: Rieske [2Fe-2S] iron-sulfur protein; n=... 33 5.5
UniRef50_Q82XB6 Cluster: NAD binding site:D-amino acid oxidase; ... 33 5.5
UniRef50_Q81TK8 Cluster: Pyridine nucleotide-disulfide oxidoredu... 33 5.5
UniRef50_Q7WHZ2 Cluster: Putative uncharacterized protein; n=3; ... 33 5.5
UniRef50_Q7URD0 Cluster: Putative uncharacterized protein; n=1; ... 33 5.5
UniRef50_Q6AAC4 Cluster: Alcohol dehydrogenase; n=1; Propionibac... 33 5.5
UniRef50_Q5WBW4 Cluster: Oxidoreductase; n=1; Bacillus clausii K... 33 5.5
UniRef50_Q1Z150 Cluster: Nitric oxide reductase; n=2; Photobacte... 33 5.5
UniRef50_Q1GD56 Cluster: Cyclic nucleotide-binding protein; n=5;... 33 5.5
UniRef50_Q18CC1 Cluster: E3 component of acetoin dehydrogenase e... 33 5.5
UniRef50_Q0RYF5 Cluster: Probable ferredoxin reductase; n=1; Rho... 33 5.5
UniRef50_Q0G6S5 Cluster: 2-octaprenyl-6-methoxyphenyl hydroxylas... 33 5.5
UniRef50_A7H7Z6 Cluster: Amine oxidase; n=2; Anaeromyxobacter|Re... 33 5.5
UniRef50_A7CRL6 Cluster: Alanine dehydrogenase; n=1; Opitutaceae... 33 5.5
UniRef50_A6GEE9 Cluster: Aerobic glycerol-3-phosphate dehydrogen... 33 5.5
UniRef50_A4A9H6 Cluster: CoxE; n=1; Congregibacter litoralis KT7... 33 5.5
UniRef50_A2U8S2 Cluster: FAD-dependent pyridine nucleotide-disul... 33 5.5
UniRef50_A0YYL2 Cluster: Glycerol-3-phosphate dehydrogenase; n=1... 33 5.5
UniRef50_A0K1Y3 Cluster: NADP oxidoreductase, coenzyme F420-depe... 33 5.5
UniRef50_A0JYP0 Cluster: Glycine oxidase ThiO; n=2; Arthrobacter... 33 5.5
UniRef50_Q0CJP5 Cluster: Predicted protein; n=2; Aspergillus|Rep... 33 5.5
UniRef50_A2R6C0 Cluster: Contig An15c0240, complete genome; n=10... 33 5.5
UniRef50_P17052 Cluster: Rubredoxin-NAD(+) reductase; n=3; Pseud... 33 5.5
UniRef50_Q6D8S1 Cluster: Nitric oxide reductase FlRd-NAD(+) redu... 33 5.5
UniRef50_Q6MD64 Cluster: Translation initiation factor IF-2; n=1... 33 5.5
UniRef50_P32191 Cluster: Glycerol-3-phosphate dehydrogenase, mit... 33 5.5
UniRef50_P35484 Cluster: Dihydrolipoyl dehydrogenase; n=3; Achol... 33 5.5
UniRef50_P37337 Cluster: Biphenyl dioxygenase system ferredoxin-... 33 5.5
UniRef50_Q8R8V6 Cluster: Uncharacterized NAD(FAD)-dependent dehy... 33 7.3
UniRef50_Q8KAS7 Cluster: NADH oxidase, putative; n=10; Bacteria|... 33 7.3
UniRef50_Q89CI2 Cluster: Blr7815 protein; n=7; Proteobacteria|Re... 33 7.3
UniRef50_Q6ADW0 Cluster: Putative uncharacterized protein; n=1; ... 33 7.3
UniRef50_Q5H1Q2 Cluster: Putative uncharacterized protein; n=6; ... 33 7.3
UniRef50_Q3BTU5 Cluster: Short chain dehydrogenase; n=1; Xanthom... 33 7.3
UniRef50_Q2RHM5 Cluster: Dihydrolipoyl dehydrogenase; n=4; Clost... 33 7.3
UniRef50_Q2GKG4 Cluster: Heme/FAD-binding domain protein; n=7; A... 33 7.3
UniRef50_Q1V3K0 Cluster: 2-octaprenyl-3-methyl-6-methoxy-1,4-ben... 33 7.3
UniRef50_Q1MF67 Cluster: Putative D-amino acid dehydrogenase pre... 33 7.3
UniRef50_Q1AR91 Cluster: CoA-binding protein; n=1; Rubrobacter x... 33 7.3
UniRef50_Q13G96 Cluster: Salicylate 1-monooxygenase; n=1; Burkho... 33 7.3
UniRef50_Q0PQK1 Cluster: Heterodisulfide reductase subunit A; n=... 33 7.3
UniRef50_A7H954 Cluster: TrkA-N domain protein; n=1; Anaeromyxob... 33 7.3
UniRef50_A5FC70 Cluster: Short-chain dehydrogenase/reductase SDR... 33 7.3
UniRef50_A4VL23 Cluster: 3-hydroxybutyrate dehydrogenase; n=1; P... 33 7.3
UniRef50_A4G2V4 Cluster: Rubredoxin-NAD(+) reductase; n=2; Oxalo... 33 7.3
UniRef50_A4E8R9 Cluster: Putative uncharacterized protein; n=1; ... 33 7.3
UniRef50_A3XFG3 Cluster: ABC transporter, permease protein; n=2;... 33 7.3
UniRef50_A3JUR9 Cluster: Transcriptional regulator, AraC family ... 33 7.3
>UniRef50_Q16836 Cluster: Hydroxyacyl-coenzyme A dehydrogenase,
mitochondrial precursor; n=40; Eukaryota|Rep:
Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial
precursor - Homo sapiens (Human)
Length = 314
Score = 215 bits (524), Expect = 1e-54
Identities = 104/194 (53%), Positives = 144/194 (74%)
Frame = +2
Query: 158 SNSSAMQSAIKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRV 337
+++SA + +K+VTVIGGGLMG+GIAQV+A G V LVD + D LAK+KK I +L +V
Sbjct: 18 ASASAKKIIVKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKV 77
Query: 338 AKKMYKDNPQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGV 517
AKK + +NP+ ++FV +L I T+TDAA S DLVVEAIVEN+ VK++LFK+LD
Sbjct: 78 AKKKFAENPKAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAIVENLKVKNELFKRLDKF 137
Query: 518 APSHTIFASNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTM 697
A HTIFASNTSSL I IA+ R+D+F GLHFFNPVPVM+L+ V+K TS+ T++++
Sbjct: 138 AAEHTIFASNTSSLQITSIANATTRQDRFAGLHFFNPVPVMKLVEVIKTPMTSQKTFESL 197
Query: 698 MEWGKSXGKTCITC 739
+++ K+ GK ++C
Sbjct: 198 VDFSKALGKHPVSC 211
>UniRef50_Q4DMG1 Cluster: Short chain 3-hydroxyacyl-coa
dehydrogenase, putative; n=2; Trypanosoma cruzi|Rep:
Short chain 3-hydroxyacyl-coa dehydrogenase, putative -
Trypanosoma cruzi
Length = 320
Score = 179 bits (436), Expect = 6e-44
Identities = 85/178 (47%), Positives = 130/178 (73%)
Frame = +2
Query: 191 NVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNPQE 370
+V V GGG MGSGIAQV+AQAG T+V+VS + L+ ++KSI ++LSR+ KK Y + Q+
Sbjct: 34 SVAVWGGGTMGSGIAQVNAQAGIPTTVVEVSQERLSASRKSIESSLSRIGKKQYPGDDQK 93
Query: 371 VEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFASNT 550
++ FV++++ RI TD A+ +A L+VEAI+E+I K L++++DG+AP +F +NT
Sbjct: 94 MKAFVDETVSRITFTTDERLAASNASLIVEAILEDIDAKKVLWRKVDGMAPKECVFCTNT 153
Query: 551 SSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXGK 724
SSLS+ E A+V R D+F GLHFF+PVP+M+L+ VVK ++TS++T ++E+ K K
Sbjct: 154 SSLSVGEQAAVTGRPDRFAGLHFFSPVPMMKLVEVVKAAKTSQSTLDRILEYAKMLNK 211
>UniRef50_Q4PFL4 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 344
Score = 175 bits (426), Expect = 9e-43
Identities = 93/201 (46%), Positives = 128/201 (63%), Gaps = 4/201 (1%)
Frame = +2
Query: 149 RNFSNSSAMQSAIKNVTVIGGGLMGSGIAQVSAQAGQ-NVTLVDVSNDALAKAKKSIGTN 325
R FS S ++N+TV G GLMG+GIAQV A G+ NVTL DV++ ALA + I +
Sbjct: 29 RAFSTSLVQNKDVQNITVFGAGLMGAGIAQVLAHKGKFNVTLSDVTDKALANGQTIISKS 88
Query: 326 LSRVAKK-MYKDNPQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFK 502
L R+ KK M + + +E ++V + I TD A K DLV+EAI+EN+G+K LF
Sbjct: 89 LGRIVKKSMAEASAEEQAQYVKGIVDSIKVTTDPEAAVKDTDLVIEAIIENVGIKKDLFG 148
Query: 503 QLDGVAPSHTIFASNTSSLSINEIASVV--KRKDKFGGLHFFNPVPVMRLLXVVKGSETS 676
LDG AP +FASNTSSLSI ++A V +R++ FGG H FNPVP M+L+ VV+ ++TS
Sbjct: 149 FLDGKAPKDALFASNTSSLSITDVAEAVSAQRQELFGGFHAFNPVPQMKLVEVVRTTKTS 208
Query: 677 EATYKTMMEWGKSXGKTCITC 739
T+ ++ E K GKT + C
Sbjct: 209 NDTFDSLTEVAKRMGKTPVAC 229
>UniRef50_P34439 Cluster: Probable 3-hydroxyacyl-CoA dehydrogenase
F54C8.1; n=2; Caenorhabditis|Rep: Probable
3-hydroxyacyl-CoA dehydrogenase F54C8.1 - Caenorhabditis
elegans
Length = 298
Score = 172 bits (419), Expect = 7e-42
Identities = 83/195 (42%), Positives = 129/195 (66%)
Frame = +2
Query: 155 FSNSSAMQSAIKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSR 334
F+ AMQ+ I+NV ++G G MGSGIAQV+A +G NV L DV+ AL +A K+I +++
Sbjct: 2 FTAKCAMQN-IRNVAIVGSGQMGSGIAQVTASSGFNVMLADVNKKALDRAMKAISQSVTH 60
Query: 335 VAKKMYKDNPQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDG 514
++KK K +E FV ++ RI T + + A ADL++EA +ENI +K +F Q++
Sbjct: 61 LSKKQ-KGTDKEKSDFVTLTMSRIKTCNNVSTAVADADLIIEAAIENIDLKRGIFAQIEQ 119
Query: 515 VAPSHTIFASNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKT 694
+I +NTSS + ++A ++ K +FGGLHFFNPVPVM+LL V++ +TS+ TY T
Sbjct: 120 SCKKDSILTTNTSSFLLEDVAKGLQDKTRFGGLHFFNPVPVMKLLEVIRSDDTSDETYAT 179
Query: 695 MMEWGKSXGKTCITC 739
++++G + GKT + C
Sbjct: 180 LIKFGTAVGKTTVAC 194
>UniRef50_Q5KBI5 Cluster: Short chain 3-hydroxyacyl-CoA
dehydrogenase, putative; n=1; Filobasidiella
neoformans|Rep: Short chain 3-hydroxyacyl-CoA
dehydrogenase, putative - Cryptococcus neoformans
(Filobasidiella neoformans)
Length = 342
Score = 171 bits (417), Expect = 1e-41
Identities = 95/205 (46%), Positives = 133/205 (64%), Gaps = 2/205 (0%)
Frame = +2
Query: 131 QFKVIVRNFSNSSAMQSAIKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKK 310
+ + R+ S +SA + ++ +TV G GLMG+GIAQV AQ G V L D L
Sbjct: 19 RLSTVQRHLSTTSATRK-VEELTVFGAGLMGAGIAQVGAQNGLKVELTD-DPAILRNGIN 76
Query: 311 SIGTNLSRVAKKMYKDNPQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKH 490
I +L+RVAKK +P ++E F N+ L I+T TD+++A ++ADLVVEAI+E+I VK
Sbjct: 77 IISKSLARVAKKK---SPDDIEGFTNNVLKNISTTTDSSQAVENADLVVEAIIESIKVKR 133
Query: 491 KLFKQLDGVAPSHTIFASNTSSLSINEIASVV--KRKDKFGGLHFFNPVPVMRLLXVVKG 664
LF LDG A S IFA+NTSSLS+ EIA +R+ KF GLHFFNPVP M+L+ +++
Sbjct: 134 DLFGFLDGKAKSDCIFATNTSSLSVTEIAEACSPERQAKFAGLHFFNPVPAMKLVEIIRT 193
Query: 665 SETSEATYKTMMEWGKSXGKTCITC 739
+TS+ TY+T+ E GK+ +TC
Sbjct: 194 PQTSQETYETLREVTLQMGKSPVTC 218
>UniRef50_Q0YNQ2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
precursor; n=3; Geobacter|Rep: 3-hydroxybutyryl-CoA
dehydrogenase precursor - Geobacter sp. FRC-32
Length = 289
Score = 159 bits (385), Expect = 9e-38
Identities = 85/185 (45%), Positives = 118/185 (63%)
Frame = +2
Query: 185 IKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNP 364
IK V + G G MG+GIAQ++A AG V +VD+S + +AKK+I +L RV KK
Sbjct: 6 IKTVGMAGAGSMGAGIAQIAAMAGLQVKVVDMSEEVWGRAKKTIVKSLERVVKK-----G 60
Query: 365 QEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFAS 544
EK + ++LGRI+ +TD A K + EA+ E+I VK +LF +LD V TI+A+
Sbjct: 61 TITEKEMEETLGRISFSTDVASL-KDVPFIFEAVFEDINVKKELFAKLDAVCGDDTIYAT 119
Query: 545 NTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXGK 724
NTSS+SI E+A++VK F G+HFFNPVPVM+L+ V+ +T+ AT +E K GK
Sbjct: 120 NTSSISITEMAALVKNPANFIGMHFFNPVPVMKLVEVIPALQTAPATKDLALEMAKKIGK 179
Query: 725 TCITC 739
T ITC
Sbjct: 180 TAITC 184
>UniRef50_UPI00015BAF7B Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=1; Ignicoccus hospitalis KIN4/I|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Ignicoccus hospitalis KIN4/I
Length = 683
Score = 157 bits (381), Expect = 3e-37
Identities = 81/198 (40%), Positives = 122/198 (61%), Gaps = 1/198 (0%)
Frame = +2
Query: 143 IVRNFSNSSAMQSAIKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGT 322
++R ++ A+Q ++ V V+G G+MG GIAQV+A +G NV ++D+ + L +A + I
Sbjct: 10 LLRLWTADQALQE-VRKVLVVGAGVMGHGIAQVAAMSGLNVRMIDIKQEFLDRAMERIKE 68
Query: 323 NLSRV-AKKMYKDNPQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLF 499
+L ++ AK K+ P+EV K + + + + AEA+K D V+EA+ E + +K +F
Sbjct: 69 SLEKLYAKGKLKEPPEEVLKRIETMVANPDDESSYAEAAKDVDFVIEAVPEKLELKRAVF 128
Query: 500 KQLDGVAPSHTIFASNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSE 679
LD AP H I ASNTSS+ I EIA KR DK G+HFFNP +++L+ VV+G ETS+
Sbjct: 129 SVLDKYAPPHAILASNTSSIPITEIAKATKRPDKVVGMHFFNPPVILKLVEVVRGKETSD 188
Query: 680 ATYKTMMEWGKSXGKTCI 733
T K +E K GK I
Sbjct: 189 ETVKITVELAKKMGKVPI 206
>UniRef50_O29077 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3;
cellular organisms|Rep: 3-hydroxyacyl-CoA dehydrogenase
- Archaeoglobus fulgidus
Length = 295
Score = 150 bits (363), Expect = 4e-35
Identities = 77/180 (42%), Positives = 116/180 (64%)
Frame = +2
Query: 185 IKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNP 364
IK + V+G G+MG GIAQV+A+ G +V +VDVS + L KA + I + + + + K
Sbjct: 6 IKVIGVVGAGVMGHGIAQVAARTGYDVVMVDVSEEVLKKAMELIESGPFGLRRLVEKGKM 65
Query: 365 QEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFAS 544
E E + RI T+T + EA K AD ++EA+ E +K K+F +LD + TI AS
Sbjct: 66 SEDE--AKAVMARIRTST-SLEALKDADFIIEAVTEKADLKKKIFAELDRICKPETIIAS 122
Query: 545 NTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXGK 724
NTS++ I+++A+ V+RKDKF G+H+FNP PVMRL+ V++G+ TS+ T+ +E K GK
Sbjct: 123 NTSAIMISDLATAVERKDKFIGMHWFNPAPVMRLIEVIRGALTSDETFNITVELSKKMGK 182
>UniRef50_A1SSP5 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
precursor; n=1; Psychromonas ingrahamii 37|Rep:
3-hydroxybutyryl-CoA dehydrogenase precursor -
Psychromonas ingrahamii (strain 37)
Length = 511
Score = 147 bits (355), Expect = 4e-34
Identities = 78/182 (42%), Positives = 119/182 (65%)
Frame = +2
Query: 188 KNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNPQ 367
K V VIG G MG+GIAQV+AQ+G V L D++ +AK++I L R KK +
Sbjct: 7 KTVAVIGAGAMGAGIAQVAAQSGYQVYLFDLAKGKAEEAKENIEKQLERRVKKGRME--- 63
Query: 368 EVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFASN 547
++ + +L RI+ +++ +E + SA+LV+EAIVEN+ +K LFK+L+ + + I ASN
Sbjct: 64 --QQTLESTLLRIHCSSELSEIA-SANLVIEAIVENLEIKQGLFKELETICSADCILASN 120
Query: 548 TSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXGKT 727
TSS+SI IAS +K ++F GLHFFNP PVM+L+ V++G T++ +T +W +S GK
Sbjct: 121 TSSISITAIASALKSPERFIGLHFFNPAPVMKLVEVIQGVATADNIAETAQQWARSCGKK 180
Query: 728 CI 733
+
Sbjct: 181 SV 182
>UniRef50_Q97UK9 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=2;
Sulfolobus|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Sulfolobus solfataricus
Length = 384
Score = 144 bits (350), Expect = 2e-33
Identities = 77/182 (42%), Positives = 116/182 (63%), Gaps = 1/182 (0%)
Frame = +2
Query: 182 AIKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKK-MYKD 358
+IK + V+G G MG GIA+VSA A NV++VD+S D L +AK+ I +L++ +K K+
Sbjct: 2 SIKKIGVVGAGTMGHGIAEVSALANYNVSVVDISWDFLNRAKERIMESLNKFYEKGQIKE 61
Query: 359 NPQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIF 538
P+++ K RI +T + + + AD V+EA+ E I +K K+F+ LD + PSHT
Sbjct: 62 KPEDIMK-------RIEFST-SYDVMRDADFVIEAVPEIIELKRKVFETLDSITPSHTFL 113
Query: 539 ASNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSX 718
ASNTSS+ I+ IA V KRK+K G+HFFNP P+M+L+ +V TS+ T + ++ K
Sbjct: 114 ASNTSSIPISTIAEVTKRKEKIIGMHFFNPPPIMKLVEIVPSKYTSDETIEVTIDLAKKM 173
Query: 719 GK 724
K
Sbjct: 174 NK 175
>UniRef50_O30218 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Archaeoglobus fulgidus|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Archaeoglobus fulgidus
Length = 661
Score = 144 bits (349), Expect = 2e-33
Identities = 78/184 (42%), Positives = 113/184 (61%), Gaps = 1/184 (0%)
Frame = +2
Query: 185 IKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMY-KDN 361
I+NV VIG G MG IA+V A G NV L+DVS D L +A + I L + ++ Y ++
Sbjct: 6 IRNVAVIGAGSMGHAIAEVVAIHGFNVKLMDVSEDQLKRAMEKIEEGLRKSYERGYISED 65
Query: 362 PQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFA 541
P++V K RI D E +K ADLV+EAI E +K K+F +++ P HTIFA
Sbjct: 66 PEKVLK-------RIEATADLIEVAKDADLVIEAIPEIFDLKKKVFSEIEQYCPDHTIFA 118
Query: 542 SNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXG 721
+NTSSLSI ++A KR +KF G+HFFNP +++LL +V G +TSE T + + ++ +
Sbjct: 119 TNTSSLSITKLAEATKRPEKFIGMHFFNPPKILKLLEIVWGEKTSEETIRIVEDFARKID 178
Query: 722 KTCI 733
+ I
Sbjct: 179 RIII 182
>UniRef50_P45856 Cluster: Probable 3-hydroxybutyryl-CoA
dehydrogenase; n=65; Bacteria|Rep: Probable
3-hydroxybutyryl-CoA dehydrogenase - Bacillus subtilis
Length = 287
Score = 144 bits (349), Expect = 2e-33
Identities = 82/183 (44%), Positives = 111/183 (60%)
Frame = +2
Query: 185 IKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNP 364
IK + V G G MGSGIAQ +A AG V + DV+ +A K + L+R A+K K
Sbjct: 3 IKQIMVAGAGQMGSGIAQTAADAGFYVRMYDVNPEAAEAGLKRLKKQLARDAEKG-KRTE 61
Query: 365 QEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFAS 544
EV+ +N RI+ + EA + AD+V+EAI EN+ K ++FK LD + P HTI AS
Sbjct: 62 TEVKSVIN----RISISQTLEEA-EHADIVIEAIAENMAAKTEMFKTLDRICPPHTILAS 116
Query: 545 NTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXGK 724
NTSSL I EIA+V R + G+HF NPVPVM+L+ V++G TSE T +M + GK
Sbjct: 117 NTSSLPITEIAAVTNRPQRVIGMHFMNPVPVMKLVEVIRGLATSEETALDVMALAEKMGK 176
Query: 725 TCI 733
T +
Sbjct: 177 TAV 179
>UniRef50_Q84T13 Cluster: L-3-hydroxyacyl-CoA dehydrogenase subunit
precursor; n=1; Euglena gracilis|Rep:
L-3-hydroxyacyl-CoA dehydrogenase subunit precursor -
Euglena gracilis
Length = 320
Score = 142 bits (344), Expect = 8e-33
Identities = 79/193 (40%), Positives = 109/193 (56%), Gaps = 3/193 (1%)
Frame = +2
Query: 170 AMQSAIKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKM 349
A + V V+G G MG GIAQ++A AG V VD+ + L+K K++ +LS+VA K
Sbjct: 17 ATAPGLSTVGVVGMGAMGHGIAQMTAAAGYKVVAVDIDANMLSKGIKAVEDSLSKVAAKA 76
Query: 350 YKDNPQE---VEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVA 520
KD + EK D RI T+ D S S DLV+E+I+E++ +K K F L VA
Sbjct: 77 VKDGKADKATAEKNAADVRSRITTSGDIGALS-SCDLVIESIIEDLNIKKKFFADLGKVA 135
Query: 521 PSHTIFASNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMM 700
++ I ASNTSS I ++ R F GLHFFNPV +M+L+ V+K +T E YK
Sbjct: 136 GANAILASNTSSFPITQLGEASGRTSNFLGLHFFNPVQMMKLVEVIKTKDTKEDVYKLGF 195
Query: 701 EWGKSXGKTCITC 739
+ KS GK + C
Sbjct: 196 AFSKSIGKEPVAC 208
>UniRef50_Q1AV58 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
precursor; n=1; Rubrobacter xylanophilus DSM 9941|Rep:
3-hydroxybutyryl-CoA dehydrogenase precursor -
Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 377
Score = 139 bits (337), Expect = 6e-32
Identities = 76/180 (42%), Positives = 111/180 (61%)
Frame = +2
Query: 188 KNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNPQ 367
+ V V+G G MGSGIAQ +A G V LVDVS +AL + +S+ NL R ++ +
Sbjct: 3 ERVAVVGAGTMGSGIAQSAAACGFEVALVDVSEEALERGMRSVRANLER---RVERGRIS 59
Query: 368 EVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFASN 547
E+ + LGRI+T T + E+ A LV+EA+VE+IGVK ++F+ L+ V + A+N
Sbjct: 60 SEER--DGVLGRISTFT-SLESCAGASLVIEAVVEDIGVKREVFRTLERVVGEEAVLATN 116
Query: 548 TSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXGKT 727
TSSLS+ EI++ +R ++ G+HFFNP PVMRL+ VV+G + E E + GKT
Sbjct: 117 TSSLSVAEISATTRRPERVVGMHFFNPAPVMRLVEVVRGPRSGEEALARAEEAARRMGKT 176
>UniRef50_O28011 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3;
Archaeoglobus fulgidus|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Archaeoglobus fulgidus
Length = 668
Score = 139 bits (337), Expect = 6e-32
Identities = 73/185 (39%), Positives = 113/185 (61%)
Frame = +2
Query: 173 MQSAIKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMY 352
++ IK V V+G GLMG GIA+V A AG NVT+ D+ + + + I +L+++ +K
Sbjct: 13 VRERIKTVAVLGAGLMGHGIAEVCAMAGYNVTMRDIKQEFVDRGMNMIKESLAKLEQKGK 72
Query: 353 KDNPQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHT 532
+ +EV L RI D EA K ADLV+EA+ E + +K ++++++D +A
Sbjct: 73 IKSAEEV-------LSRIKPTVDLEEAVKDADLVIEAVPEVVEIKKQVWEEVDKLAKPDC 125
Query: 533 IFASNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGK 712
IF SNTS++ I +A R +KF GLHFFNP +MRL+ V++G +TS+ ++E+ K
Sbjct: 126 IFTSNTSTMRITMLADFTSRPEKFAGLHFFNPPVLMRLVEVIRGEKTSDEVMDLLVEFVK 185
Query: 713 SXGKT 727
S GKT
Sbjct: 186 SIGKT 190
>UniRef50_Q978T2 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=5;
Archaea|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Thermoplasma volcanium
Length = 659
Score = 138 bits (335), Expect = 1e-31
Identities = 74/180 (41%), Positives = 108/180 (60%)
Frame = +2
Query: 185 IKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNP 364
I VTVIG G+MG GIA+ A AG +V L D+S+D LAKAK I +L R+ K +
Sbjct: 3 ISKVTVIGSGIMGHGIAETIALAGYDVNLEDISDDVLAKAKAEIDASLDRLVKSGKLSDK 62
Query: 365 QEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFAS 544
+V LGRI+ T E+ K ADLV+EA+ E + +K ++F QLD I A+
Sbjct: 63 TKV-------LGRIHYFTSIPESVKDADLVIEAVPEILDIKRQVFAQLDQSTKEDAILAT 115
Query: 545 NTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXGK 724
NTS++ + EIA VK+K K G+HFFNP V++L+ V++ T + ++ + ++ K GK
Sbjct: 116 NTSNIRLTEIAEGVKKKGKVVGMHFFNPPVVLKLVEVIRSDYTEDEVFEAVYDFSKKIGK 175
>UniRef50_Q891F6 Cluster: 3-hydroxybutyryl-coA dehydrogenase; n=3;
Bacteria|Rep: 3-hydroxybutyryl-coA dehydrogenase -
Clostridium tetani
Length = 282
Score = 136 bits (329), Expect = 5e-31
Identities = 71/180 (39%), Positives = 108/180 (60%)
Frame = +2
Query: 185 IKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNP 364
+K + V+G G MG+GIAQ A G V L D+ ++ + + K I LS++ K
Sbjct: 1 MKKICVLGAGTMGAGIAQAFAAKGYEVVLRDIKDEFVERGIKGIEKGLSKLVSK-----G 55
Query: 365 QEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFAS 544
+ ++ ++ LGRI D +A+ DLVVEA +EN+ +K ++F +LD + TI +S
Sbjct: 56 RMAQEDMDSILGRIEGTVDLNKAA-DCDLVVEAAIENMEIKREIFAELDRICKPETILSS 114
Query: 545 NTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXGK 724
NTSSLSI EIA+ R DK G+HFFNP PVM+L+ +++G TS+ T+ + E + GK
Sbjct: 115 NTSSLSITEIATATNRPDKVIGMHFFNPAPVMKLIEIIRGMATSQETFDAVKEVSVAIGK 174
>UniRef50_Q9HKW7 Cluster: Probable 3-hydroxyacyl-CoA dehydrogenase;
n=2; Thermoplasmatales|Rep: Probable 3-hydroxyacyl-CoA
dehydrogenase - Thermoplasma acidophilum
Length = 291
Score = 136 bits (329), Expect = 5e-31
Identities = 73/181 (40%), Positives = 112/181 (61%)
Frame = +2
Query: 185 IKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNP 364
I+ V+G G+MG GIAQV A++G VT++DV +D LA A +SI + + K
Sbjct: 3 IRTTAVVGSGVMGQGIAQVFARSGYPVTIIDVRDDILANAVRSIKEGRYGLMNLVKKGTM 62
Query: 365 QEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFAS 544
E E V+ +G+I T+T S AD+VVEA+ EN+ +K K+F ++ + I AS
Sbjct: 63 TESE--VDKIMGKIRTSTSYGSLS-DADIVVEAVPENLDLKRKVFIDIEKNVSENAIIAS 119
Query: 545 NTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXGK 724
NTS ++I EIA +K+KD+ G+H+FNP +M+L+ VV+ TSE T T++++ + GK
Sbjct: 120 NTSGITIAEIAQDLKKKDRAIGMHWFNPAGIMKLIEVVRAKMTSEDTISTVVDFSRRIGK 179
Query: 725 T 727
T
Sbjct: 180 T 180
>UniRef50_Q5L0D2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=3;
Bacteria|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Geobacillus kaustophilus
Length = 281
Score = 136 bits (328), Expect = 7e-31
Identities = 72/182 (39%), Positives = 103/182 (56%)
Frame = +2
Query: 188 KNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNPQ 367
+ + VIG G+MGSGIAQ +A G+ V L DVS AL S +L R K P+
Sbjct: 3 ETIAVIGAGVMGSGIAQTAAMVGKTVYLYDVSEAALQNGLASAEKSLRRFVKTGGLSEPE 62
Query: 368 EVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFASN 547
+LGRI + D AEA + AD+V+EA+ EN+ +K +F+QLD +A I A+N
Sbjct: 63 -----ARAALGRIRSTVDLAEAVRGADVVIEAVPENLALKKDVFQQLDQLAKPDAILATN 117
Query: 548 TSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXGKT 727
TS LS+ +A+ R + G+H+FNP PVM+L+ +VKG TS+ T + GK
Sbjct: 118 TSELSVTALAAATNRPENVIGMHWFNPAPVMKLIEIVKGETTSDDTVDAIRRLSVELGKE 177
Query: 728 CI 733
+
Sbjct: 178 TV 179
>UniRef50_A6ERZ1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
unidentified eubacterium SCB49|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - unidentified eubacterium SCB49
Length = 403
Score = 136 bits (328), Expect = 7e-31
Identities = 74/189 (39%), Positives = 116/189 (61%)
Frame = +2
Query: 158 SNSSAMQSAIKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRV 337
S + QS I N+ +IG G MGSGIAQV+A AG V L D++ AL KAK S+ ++R+
Sbjct: 8 STINNQQSPINNIGIIGAGTMGSGIAQVAATAGCTVKLFDLNQAALDKAKASLEKIMTRL 67
Query: 338 AKKMYKDNPQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGV 517
+K ++ + +++ +N + A++ DL +EAI+E++G+K K+F++L+
Sbjct: 68 VEKGRVTEEEKAR--IQENISYVNALKELADS----DLTIEAIIEDLGIKKKVFQELESY 121
Query: 518 APSHTIFASNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTM 697
I ASNTSSLSI IAS +++ ++ G+HFFNP P+M+L+ V+ +TS+A K
Sbjct: 122 VSDSCIIASNTSSLSIASIASSLQKPERCVGIHFFNPAPLMKLVEVIPAIQTSDAVLKIS 181
Query: 698 MEWGKSXGK 724
E KS K
Sbjct: 182 EETIKSWKK 190
>UniRef50_Q39NP5 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=54;
cellular organisms|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Burkholderia sp. (strain 383)
(Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 /
R18194))
Length = 284
Score = 135 bits (326), Expect = 1e-30
Identities = 74/184 (40%), Positives = 117/184 (63%)
Frame = +2
Query: 182 AIKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDN 361
AI+ V V+G G MG+GIAQ +A AG NV ++DVS+ AL K ++ +L R+ K D
Sbjct: 2 AIEIVGVVGAGTMGNGIAQTAAVAGLNVVMIDVSDAALEKGIATLKGSLDRLVSKDKLDA 61
Query: 362 PQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFA 541
+ +L RI T+TD A+ + +AD+V+EA EN+ +K ++ KQ++ VA + I A
Sbjct: 62 ATR-----DAALARITTSTDYAKLA-AADIVIEAATENVELKGRILKQIEAVARAEAIIA 115
Query: 542 SNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXG 721
+NTSS+SI +A+ + +F G+HFFNPVP+M L+ +++G +TS+AT + E +
Sbjct: 116 TNTSSISITALAAPLADPARFVGMHFFNPVPLMPLVEIIRGLQTSDATASAVRELTERFD 175
Query: 722 KTCI 733
K+ I
Sbjct: 176 KSPI 179
>UniRef50_Q11TH9 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=16;
Bacteroidetes|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Cytophaga hutchinsonii (strain ATCC 33406 / NCIMB 9469)
Length = 298
Score = 134 bits (324), Expect = 2e-30
Identities = 79/178 (44%), Positives = 105/178 (58%), Gaps = 1/178 (0%)
Frame = +2
Query: 173 MQSAIKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSR-VAKKM 349
MQ+ K + +IG G MGSGIA AQ G V L D + AL KA I TNL R ++K +
Sbjct: 1 MQNTHKYILIIGSGTMGSGIAHSFAQFGFQVFLCDSNAAALNKAMLQISTNLERQISKGI 60
Query: 350 YKDNPQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSH 529
D+ +E + RI TD EA+K+ LVVEA+ E + +K LFK+LD P
Sbjct: 61 IPDSEKET------IISRITPITDFKEAAKTVSLVVEAVPELLEIKADLFKELDMHCPPE 114
Query: 530 TIFASNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMME 703
TI ASNTSS+SI +AS R +K G+HF NPVPVM+L+ ++ G TS T + + E
Sbjct: 115 TILASNTSSISITTLASYTSRPEKVIGMHFMNPVPVMQLVEIINGLLTSSETTRRIEE 172
>UniRef50_Q9KBD3 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=8;
Bacteria|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Bacillus halodurans
Length = 287
Score = 134 bits (323), Expect = 3e-30
Identities = 74/180 (41%), Positives = 112/180 (62%)
Frame = +2
Query: 185 IKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNP 364
I V V+G G MGSGIA ++A +G V L+D+ ++ L A + I T + K + K
Sbjct: 3 IHTVGVVGAGTMGSGIANLAAMSGLQVVLLDLDDNQLDIAWQKINTFME---KSVAKGKM 59
Query: 365 QEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFAS 544
E EK +LGRI + T E ++ ADLV+EA++EN+ VK ++F LD + TI A+
Sbjct: 60 SEAEK--EAALGRIKSTTTYEELAE-ADLVIEAVIENLDVKKEVFHTLDTCLANDTIIAT 116
Query: 545 NTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXGK 724
NTSS+SI EIA+ R D+ G+HFFNP +M+L+ VV+G +TS+ T +T+ ++ + K
Sbjct: 117 NTSSMSITEIAAATNRPDRVVGMHFFNPAQLMKLVEVVRGYQTSDDTVETVKQFARQLKK 176
>UniRef50_Q67SZ4 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Symbiobacterium thermophilum|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Symbiobacterium thermophilum
Length = 517
Score = 131 bits (316), Expect = 2e-29
Identities = 71/180 (39%), Positives = 112/180 (62%)
Frame = +2
Query: 185 IKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNP 364
++ + V+G G MG+GIAQV+AQ+G +V L DV +ALA+A + ++L R A + +
Sbjct: 1 MRRLGVVGAGTMGAGIAQVAAQSGFDVLLYDVDPEALARALGRVESDLQRQAARGRIPDA 60
Query: 365 QEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFAS 544
Q V + LGRI T T + + +AD V+EA E++ +K +LF++LD + + A+
Sbjct: 61 Q-----VAEVLGRITTTTSLGDFA-AADFVIEAAPEDLELKRRLFERLDRLCREDVVLAT 114
Query: 545 NTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXGK 724
NTSSLS+ +I ++ R D+ G+HFFNPVP MRL+ VV G + EA + + ++ GK
Sbjct: 115 NTSSLSVTQIGALAGRADRVVGMHFFNPVPAMRLVEVVGGDASGEAALQATVSLAEAMGK 174
>UniRef50_Q1QBD7 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
precursor; n=2; Psychrobacter|Rep: 3-hydroxybutyryl-CoA
dehydrogenase precursor - Psychrobacter cryohalolentis
(strain K5)
Length = 533
Score = 130 bits (315), Expect = 3e-29
Identities = 66/179 (36%), Positives = 109/179 (60%)
Frame = +2
Query: 185 IKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNP 364
+K++ +IG G+MG GIAQ++AQ G V L D A + ++S+ L ++A K +
Sbjct: 3 VKSLAIIGTGIMGMGIAQIAAQVGIQVLLFDAKAGAAEQGRQSLQAMLEKLAAKGKFTDE 62
Query: 365 QEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFAS 544
Q + +L + D A+ ++ AD+V+EAI+EN+ +K +LFKQL+ + P+ TI A+
Sbjct: 63 Q-----LQSTLKNLIVIEDIAKIAE-ADVVIEAIIENLEIKQQLFKQLESIVPAETILAT 116
Query: 545 NTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXG 721
NTSSL++ IAS + ++ G HFFNPVP+M+++ V+ G T + +T+ K G
Sbjct: 117 NTSSLAVTAIASNCEHPERVAGFHFFNPVPLMKIVEVIPGISTKSSVVETLTSLAKRMG 175
>UniRef50_Q4J6T7 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2;
Archaea|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Sulfolobus acidocaldarius
Length = 657
Score = 130 bits (314), Expect = 3e-29
Identities = 74/183 (40%), Positives = 105/183 (57%), Gaps = 1/183 (0%)
Frame = +2
Query: 179 SAIKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVA-KKMYK 355
S I V V+G G MG GIA+V A AG NV L DV+ D L A + I +L ++ K+ K
Sbjct: 2 SQISRVGVVGAGTMGHGIAEVVAIAGFNVVLTDVNEDILRNALEKIRWSLEKLREKRQIK 61
Query: 356 DNPQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTI 535
+NP V L RI T + S D ++EA +E VK K+F +LD V I
Sbjct: 62 ENPNTV-------LSRIKTTVSFGDFS-DVDFIIEAAIERSDVKRKIFSELDRVVKKDAI 113
Query: 536 FASNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKS 715
FA+NTS++ I+ +A V R++KF GLHF NP +M L+ ++ G++T+E T KT ++ K
Sbjct: 114 FATNTSTIPISYLAEVTGRQEKFIGLHFMNPPVLMPLVEIIMGNKTAEETLKTTIDLAKK 173
Query: 716 XGK 724
K
Sbjct: 174 INK 176
>UniRef50_Q47DJ5 Cluster: Enoyl-CoA
hydratase/isomerase:3-hydroxyacyl-CoA dehydrogenase, C-
terminal:3-hydroxyacyl-CoA dehydrogenase, NAD-binding;
n=1; Dechloromonas aromatica RCB|Rep: Enoyl-CoA
hydratase/isomerase:3-hydroxyacyl-CoA dehydrogenase, C-
terminal:3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Dechloromonas aromatica (strain RCB)
Length = 705
Score = 129 bits (312), Expect = 6e-29
Identities = 80/197 (40%), Positives = 111/197 (56%), Gaps = 4/197 (2%)
Frame = +2
Query: 155 FSNSSAMQSAIKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDAL----AKAKKSIGT 322
F A +++ V+G G+MG GIA SA G V L D+S L A+AKK IG
Sbjct: 294 FGRHRANARRVRSAAVLGAGIMGGGIAFTSALKGVPVRLKDISRQQLDLGMAEAKKQIGR 353
Query: 323 NLSRVAKKMYKDNPQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFK 502
+ + ++ + Q+V L I D A S DLVVEAI+EN+ VKH +
Sbjct: 354 QIK--SGRVSEAKGQQV-------LTSIQPQLDYAGFS-DCDLVVEAIIENLKVKHAVLS 403
Query: 503 QLDGVAPSHTIFASNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEA 682
+L+ T+ ASNTSSL I+EIA ++R + F G+HFFNPVPVM L+ V+KGS TS+
Sbjct: 404 ELEQAVAPDTVIASNTSSLRIDEIAMPLQRPENFVGMHFFNPVPVMALVEVIKGSRTSDV 463
Query: 683 TYKTMMEWGKSXGKTCI 733
T +++ + GKT I
Sbjct: 464 AVSTAVDYAVTMGKTPI 480
>UniRef50_Q1ISD6 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
precursor; n=1; Acidobacteria bacterium Ellin345|Rep:
3-hydroxybutyryl-CoA dehydrogenase precursor -
Acidobacteria bacterium (strain Ellin345)
Length = 293
Score = 129 bits (311), Expect = 8e-29
Identities = 69/181 (38%), Positives = 111/181 (61%), Gaps = 1/181 (0%)
Frame = +2
Query: 185 IKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKK-MYKDN 361
IK+V VIG GLMGSGIAQ +A AG V +++ L + + +L++ A+K ++
Sbjct: 3 IKSVGVIGCGLMGSGIAQAAATAGFPVIVLEAEQRFLDRGFTGVERSLAKFAEKGTITES 62
Query: 362 PQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFA 541
P + R+ T+ + + D+++EAI+EN+ KHK++ L+ VA IFA
Sbjct: 63 PDAIR-------ARLKGTTNVEDLA-DCDIIIEAILENVPEKHKMYAALEKVAKPDAIFA 114
Query: 542 SNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXG 721
SNTSS+SI E+ + KR ++F GLHFFNPVP+M+L+ V++ TS+ ++ +++G G
Sbjct: 115 SNTSSISITELMAATKRPERFIGLHFFNPVPLMKLVEVIRTIATSDEVFEAAVDFGTKLG 174
Query: 722 K 724
K
Sbjct: 175 K 175
>UniRef50_A0LSM1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=5;
Actinomycetales|Rep: 3-hydroxybutyryl-CoA dehydrogenase
- Acidothermus cellulolyticus (strain ATCC 43068 / 11B)
Length = 301
Score = 129 bits (311), Expect = 8e-29
Identities = 75/183 (40%), Positives = 110/183 (60%)
Frame = +2
Query: 185 IKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNP 364
I+ V V+G GLMGSGIAQV+A AG V L D+ AL +A +I +L R+A+K K +
Sbjct: 7 IRTVGVVGSGLMGSGIAQVAAVAGYAVRLHDIEESALHRALTTIDESLHRLARKG-KLST 65
Query: 365 QEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFAS 544
+VE + RI T A+ + S D+VVEA+ E + VK +F +L + + + AS
Sbjct: 66 SDVEA----AKARITTTRRLADLADS-DVVVEAVYEELDVKRVVFAELAAIVRPNVLLAS 120
Query: 545 NTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXGK 724
NT+++ I IAS V + G+HFF+PVPVM+L +V+G +T + T + +S GK
Sbjct: 121 NTTAIPITHIASGVSGPQRVVGMHFFSPVPVMQLCEIVRGLQTDDDTVARARRFAESLGK 180
Query: 725 TCI 733
TCI
Sbjct: 181 TCI 183
>UniRef50_P40939 Cluster: Trifunctional enzyme subunit alpha,
mitochondrial precursor (TP-alpha) (78 kDa
gastrin-binding protein) [Includes: Long-chain enoyl-CoA
hydratase (EC 4.2.1.17); Long chain 3-hydroxyacyl-CoA
dehydrogenase (EC 1.1.1.211)]; n=29; Eumetazoa|Rep:
Trifunctional enzyme subunit alpha, mitochondrial
precursor (TP-alpha) (78 kDa gastrin-binding protein)
[Includes: Long-chain enoyl-CoA hydratase (EC 4.2.1.17);
Long chain 3-hydroxyacyl-CoA dehydrogenase (EC
1.1.1.211)] - Homo sapiens (Human)
Length = 763
Score = 128 bits (310), Expect = 1e-28
Identities = 69/188 (36%), Positives = 111/188 (59%)
Frame = +2
Query: 170 AMQSAIKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKM 349
A Q +K++ ++G GLMG+GIAQVS G L D + AL + ++ + L+ KK
Sbjct: 356 APQKDVKHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRGQQQVFKGLNDKVKK- 414
Query: 350 YKDNPQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSH 529
+ + F DS+ T + + AD+V+EA+ E++ +KH++ K+++ V P H
Sbjct: 415 -----KALTSFERDSIFSNLTGQLDYQGFEKADMVIEAVFEDLSLKHRVLKEVEAVIPDH 469
Query: 530 TIFASNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWG 709
IFASNTS+L I+EIA+V KR +K G+H+F+PV M+LL ++ +TS+ T + + G
Sbjct: 470 CIFASNTSALPISEIAAVSKRPEKVIGMHYFSPVDKMQLLEIITTEKTSKDTSASAVAVG 529
Query: 710 KSXGKTCI 733
GK I
Sbjct: 530 LKQGKVII 537
>UniRef50_O44608 Cluster: Hydroxy-acyl-coa dehydrogenase protein 1;
n=2; Caenorhabditis|Rep: Hydroxy-acyl-coa dehydrogenase
protein 1 - Caenorhabditis elegans
Length = 299
Score = 128 bits (308), Expect = 2e-28
Identities = 69/180 (38%), Positives = 101/180 (56%), Gaps = 3/180 (1%)
Frame = +2
Query: 194 VTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNPQE- 370
V + G G+MGSGIAQV QAG V L S L +A+++I NL RVA K D P E
Sbjct: 13 VAIFGAGMMGSGIAQVCLQAGYPVNLYGRSEKKLLEARETIKKNLIRVASKKKTDVPMEP 72
Query: 371 --VEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFAS 544
+E+ L + TD A++ A + +EA+ EN+ +K +F+ + P + + +
Sbjct: 73 AALEEIAQIQLDLLQIHTDIPSAAEDAAMAIEAVAENLDLKLDIFQTIQKTCPQNCMLIT 132
Query: 545 NTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXGK 724
NTSSL ++++ V++ F GLHFFNPVPVM+L+ VV ETS T + + K K
Sbjct: 133 NTSSLKLSQMLPVIQNPALFAGLHFFNPVPVMKLVEVVSTDETSPETTNFLFNFCKEIKK 192
>UniRef50_Q1IIH2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=5;
cellular organisms|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Acidobacteria bacterium (strain
Ellin345)
Length = 282
Score = 127 bits (307), Expect = 2e-28
Identities = 76/183 (41%), Positives = 107/183 (58%), Gaps = 2/183 (1%)
Frame = +2
Query: 185 IKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSR-VAK-KMYKD 358
I+ V VIG G MG+GIA V A++G V L DV + L + +I NL R VAK K+ ++
Sbjct: 3 IRKVGVIGAGTMGNGIAHVFAKSGYKVVLCDVKREFLDRGLATIKKNLEREVAKNKISQE 62
Query: 359 NPQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIF 538
Q + +L R + A D+VVEA E +K +LF+ LD + I
Sbjct: 63 QGQVAADHIYPTLERKDLA--------DCDIVVEAASERFEIKAELFRDLDSICRPDVIL 114
Query: 539 ASNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSX 718
A+NTSS+SI +IA+V KR DK G+HFFNPVPVM+L+ V++G TS+ TY+ + +
Sbjct: 115 ATNTSSISITKIAAVTKRPDKVIGMHFFNPVPVMKLVEVIRGLATSDETYQAVKVLSEKL 174
Query: 719 GKT 727
KT
Sbjct: 175 EKT 177
>UniRef50_P45364 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=13;
Clostridia|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Clostridium difficile
Length = 281
Score = 127 bits (307), Expect = 2e-28
Identities = 73/177 (41%), Positives = 102/177 (57%)
Frame = +2
Query: 194 VTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNPQEV 373
+ VIG G MGSGI Q A G +V L + A+ K + NL+++ K +
Sbjct: 3 LAVIGSGTMGSGIVQTFASCGHDVCLKSRTQGAIDKCLALLDKNLTKLVTKGKWMKATKA 62
Query: 374 EKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFASNTS 553
E L +++ T+ E K DL++EA VE++ +K +FK LD + TI A+NTS
Sbjct: 63 E-----ILSHVSSTTNY-EDLKDMDLIIEASVEDMNIKKDVFKLLDELCKEDTILATNTS 116
Query: 554 SLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXGK 724
SLSI EIAS KR DK G+HFFNPVP+M+L+ V+ G TS+ T+ T+ E KS K
Sbjct: 117 SLSITEIASSTKRPDKVIGMHFFNPVPMMKLVEVISGQLTSKVTFDTVFELSKSINK 173
>UniRef50_Q11E57 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor; n=1; Mesorhizobium sp. BNC1|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding precursor -
Mesorhizobium sp. (strain BNC1)
Length = 485
Score = 127 bits (306), Expect = 3e-28
Identities = 71/179 (39%), Positives = 105/179 (58%), Gaps = 4/179 (2%)
Frame = +2
Query: 191 NVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNPQE 370
++ VIG G MG+GIAQV+A AG V L DV++ A A + L+ + K+ +
Sbjct: 10 SIGVIGAGTMGAGIAQVAAAAGHKVLLFDVASGAAASGLERTAKELATLVKRGKME---- 65
Query: 371 VEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFASNT 550
+K + +GRI A + + +A L VEAIVE + VK K+F QL+ + I A+NT
Sbjct: 66 -QKRAEEIIGRITIAEKLEDLAPAA-LTVEAIVERLDVKQKVFAQLEAILAEDAILATNT 123
Query: 551 SSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETS----EATYKTMMEWGKS 715
SS+SI I + +KR ++ G+HFFNP P+M+L+ VV G TS + T+ T WGK+
Sbjct: 124 SSISITAIGAALKRPERLVGMHFFNPAPIMKLVEVVSGLATSPEVAQITHATARAWGKT 182
>UniRef50_Q1GGC1 Cluster: 3-hydroxyacyl-CoA dehydrogenase
NAD-binding; n=4; Alphaproteobacteria|Rep:
3-hydroxyacyl-CoA dehydrogenase NAD-binding -
Silicibacter sp. (strain TM1040)
Length = 733
Score = 126 bits (305), Expect = 4e-28
Identities = 70/184 (38%), Positives = 109/184 (59%)
Frame = +2
Query: 182 AIKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDN 361
++K + V+G G+MG+GIA VSAQAG V L+D DA K K T + + K+ K
Sbjct: 325 SVKKIGVLGAGMMGAGIALVSAQAGMEVVLIDRDQDAADKGKAYSATYMDKGIKRG-KAT 383
Query: 362 PQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFA 541
P++ E L +I TAT +A K DL++EA+ E+ GVK ++ K+++ + P IFA
Sbjct: 384 PEKKEAL----LAQI-TATADLDALKGCDLIIEAVFEDPGVKAEMTKKVEAIIPEDCIFA 438
Query: 542 SNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXG 721
SNTS+L I +A R ++F G+HFF+PV M L+ ++KG +T + +++ +
Sbjct: 439 SNTSTLPITSLAEASVRPEQFIGIHFFSPVEKMFLVEIIKGEKTGDRAVAKALDYVRQIR 498
Query: 722 KTCI 733
KT I
Sbjct: 499 KTPI 502
>UniRef50_P76083 Cluster: Probable 3-hydroxybutyryl-CoA
dehydrogenase; n=8; Enterobacteriaceae|Rep: Probable
3-hydroxybutyryl-CoA dehydrogenase - Escherichia coli
(strain K12)
Length = 475
Score = 126 bits (305), Expect = 4e-28
Identities = 78/190 (41%), Positives = 107/190 (56%), Gaps = 1/190 (0%)
Frame = +2
Query: 173 MQSAIKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNL-SRVAKKM 349
M ++ V VIG G MG+GIA+V+A G V L D+S +AL +A I L SRV +
Sbjct: 1 MMINVQTVAVIGSGTMGAGIAEVAASHGHQVLLYDISAEALTRAIDGIHARLNSRVTRG- 59
Query: 350 YKDNPQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSH 529
K + E+ +L R+ TD A +ADLV+EA E + VK LF QL V P
Sbjct: 60 -KLTAETCER----TLKRLIPVTDI-HALAAADLVIEAASERLEVKKALFAQLAEVCPPQ 113
Query: 530 TIFASNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWG 709
T+ +NTSS+SI IA+ +K ++ GLHFFNP PVM+L+ VV G T+ + + E
Sbjct: 114 TLLTTNTSSISITAIAAEIKNPERVAGLHFFNPAPVMKLVEVVSGLATAAEVVEQLCELT 173
Query: 710 KSXGKTCITC 739
S GK + C
Sbjct: 174 LSWGKQPVRC 183
>UniRef50_Q8XI27 Cluster: Beta-hydroxybutyryl-CoA dehydrogenase
NAD-dependent; n=9; Clostridiales|Rep:
Beta-hydroxybutyryl-CoA dehydrogenase NAD-dependent -
Clostridium perfringens
Length = 282
Score = 126 bits (303), Expect = 7e-28
Identities = 68/181 (37%), Positives = 105/181 (58%)
Frame = +2
Query: 185 IKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNP 364
++ + VIG G MG+GI Q AQ G V + D+ ++ + + I L+++ K K
Sbjct: 1 MEKIFVIGAGTMGAGIVQAFAQKGYEVIVRDIKDEFVDRGIAGINKGLTKLVSKG-KITE 59
Query: 365 QEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFAS 544
++ E L +I TD A+ DLV+EA VEN+ +K ++F +LD + TI AS
Sbjct: 60 EDKEAV----LSKITGTTDLGLAA-DCDLVIEAAVENMEIKKQIFAELDKICKEETILAS 114
Query: 545 NTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXGK 724
NTSSLSI E+AS R D+ G+HFFNP +M+L+ V++G TS+ T+ + ++ GK
Sbjct: 115 NTSSLSITEVASATNRPDRVIGMHFFNPATIMKLVEVIRGMATSQETFDKVKAMSEAIGK 174
Query: 725 T 727
T
Sbjct: 175 T 175
>UniRef50_A2TU34 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=4;
Flavobacteria|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Dokdonia donghaensis MED134
Length = 394
Score = 126 bits (303), Expect = 7e-28
Identities = 71/170 (41%), Positives = 107/170 (62%)
Frame = +2
Query: 185 IKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNP 364
IKN+ +IG G MGSGIAQV+A AG V L DV+ +AL KAK+++ L R+ +K D
Sbjct: 2 IKNIGIIGAGTMGSGIAQVAATAGCAVKLFDVNQEALDKAKEALEKVLKRLIEKGRIDAS 61
Query: 365 QEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFAS 544
++ + ++ + T + A +ADL +EAIVEN+ VK K+F++L+ I AS
Sbjct: 62 EKDR--IQANITYVTTLKELA----NADLTIEAIVENLEVKKKVFQELETYVSDTAIIAS 115
Query: 545 NTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKT 694
NTSSLSI IA+ ++ ++ G+HFFNP P+M+L+ V+ +TS+ T
Sbjct: 116 NTSSLSIASIAASLQNPERCIGIHFFNPAPLMKLVEVIPAVQTSQNVLDT 165
>UniRef50_Q64428 Cluster: Trifunctional enzyme subunit alpha,
mitochondrial precursor (TP-alpha) [Includes: Long-chain
enoyl-CoA hydratase (EC 4.2.1.17); Long chain 3-
hydroxyacyl-CoA dehydrogenase (EC 1.1.1.211)]; n=43;
Bilateria|Rep: Trifunctional enzyme subunit alpha,
mitochondrial precursor (TP-alpha) [Includes: Long-chain
enoyl-CoA hydratase (EC 4.2.1.17); Long chain 3-
hydroxyacyl-CoA dehydrogenase (EC 1.1.1.211)] - Rattus
norvegicus (Rat)
Length = 763
Score = 126 bits (303), Expect = 7e-28
Identities = 67/188 (35%), Positives = 111/188 (59%)
Frame = +2
Query: 170 AMQSAIKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKM 349
A Q ++ + ++G GLMG+GIAQVS G L D + L + ++ + L+ KK
Sbjct: 356 APQKTVQQLAILGAGLMGAGIAQVSVDKGLKTLLKDTTVTGLGRGQQQVFKGLNDKVKKK 415
Query: 350 YKDNPQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSH 529
+ + F N +G+++ + + AD+V+EA+ E++ VKHK+ K+++ V P H
Sbjct: 416 ALTSFERDSIFSN-LIGQLDY-----KGFEKADMVIEAVFEDLAVKHKVLKEVESVTPEH 469
Query: 530 TIFASNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWG 709
IFASNTS+L IN+IA+V +R +K G+H+F+PV M+LL ++ +TS+ T + + G
Sbjct: 470 CIFASNTSALPINQIAAVSQRPEKVIGMHYFSPVDKMQLLEIITTDKTSKDTTASAVAVG 529
Query: 710 KSXGKTCI 733
GK I
Sbjct: 530 LKQGKVII 537
>UniRef50_A0RUN1 Cluster: 3-hydroxyacyl-CoA dehydrogenase/enoyl-CoA
hydratase; n=4; Crenarchaeota|Rep: 3-hydroxyacyl-CoA
dehydrogenase/enoyl-CoA hydratase - Cenarchaeum
symbiosum
Length = 365
Score = 125 bits (302), Expect = 1e-27
Identities = 69/174 (39%), Positives = 101/174 (58%)
Frame = +2
Query: 218 MGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNPQEVEKFVNDSL 397
MG GIAQVSA +G V L D+ L A + I +L ++A K + +E + +N
Sbjct: 1 MGHGIAQVSAASGYEVVLRDIEQRFLDSAMEKIRWSLDKMASKG-RITAEEKDGILN--- 56
Query: 398 GRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFASNTSSLSINEIA 577
RI EA + ADLV+EA+ E + +K K++ +LD AP FASNTS+L I EIA
Sbjct: 57 -RIRPVVALGEALEGADLVIEAVPEVMDLKRKVYAELDAAAPEGAAFASNTSTLPITEIA 115
Query: 578 SVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXGKTCITC 739
R ++F G+HFFNP +M+L+ V+ G TS+ T + +E+ +S GK + C
Sbjct: 116 QATSRPERFIGIHFFNPPQLMKLVEVIPGEGTSDETTRMTLEYVESLGKQAVLC 169
>UniRef50_Q45223 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=92;
cellular organisms|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Bradyrhizobium japonicum
Length = 293
Score = 125 bits (301), Expect = 1e-27
Identities = 75/185 (40%), Positives = 106/185 (57%), Gaps = 1/185 (0%)
Frame = +2
Query: 173 MQSAIKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSR-VAKKM 349
M + IK V VIG G MG+GIA V+A AG +V L DVS D L +I NL+R V+KK+
Sbjct: 1 MAAVIKKVGVIGAGQMGNGIAHVAALAGFDVVLNDVSADRLKSGMATINGNLARQVSKKV 60
Query: 350 YKDNPQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSH 529
E+ +L RI A + + DLV+E VE VK K+F +L V
Sbjct: 61 V------TEEAKTKALSRI-VAAEKLDDLADCDLVIETAVEKEEVKRKIFHELCAVLKPE 113
Query: 530 TIFASNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWG 709
I AS+TSS+SI +A+ R ++F G+HF NPVP+M L+ +++G T +AT++ E+
Sbjct: 114 AIVASDTSSISITRLAAATDRPERFIGIHFMNPVPLMELVELIRGIATDDATFEASKEFV 173
Query: 710 KSXGK 724
GK
Sbjct: 174 AKLGK 178
>UniRef50_A3YFA8 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Marinomonas sp. MED121|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Marinomonas sp. MED121
Length = 545
Score = 124 bits (299), Expect = 2e-27
Identities = 74/183 (40%), Positives = 109/183 (59%), Gaps = 4/183 (2%)
Frame = +2
Query: 191 NVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNPQE 370
++ V+G G MG+GIAQV++QAG V L D + +A +AK+SI L+ KK+ K
Sbjct: 16 HIGVVGAGAMGAGIAQVASQAGHKVFLYDQNEEASFRAKESISLLLN---KKVAKGTI-- 70
Query: 371 VEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFASNT 550
+ + + I + + KSADL++EAIVE + +K LF+ L+ + I ASNT
Sbjct: 71 TREHYDTCIANI-IPLHSLDELKSADLIIEAIVETLEIKQSLFRALELICKPECILASNT 129
Query: 551 SSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSET----SEATYKTMMEWGKSX 718
SS+SI IAS +K ++F GLHFFNP PVM L+ V+ G + ++ Y T + WGK+
Sbjct: 130 SSISITAIASCLKYPERFLGLHFFNPAPVMPLVEVISGLASDQLIAKQLYDTCLLWGKTP 189
Query: 719 GKT 727
KT
Sbjct: 190 VKT 192
>UniRef50_A0IJE2 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor; n=5; Gammaproteobacteria|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding precursor -
Serratia proteamaculans 568
Length = 506
Score = 124 bits (299), Expect = 2e-27
Identities = 67/182 (36%), Positives = 102/182 (56%)
Frame = +2
Query: 194 VTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNPQEV 373
V VIG G MG GIAQV+A AG V L D++ A A++++G R+ +++
Sbjct: 10 VAVIGAGTMGIGIAQVAAAAGHQVQLFDIAASA---ARQALGALAQRLRQRVAAGKADAT 66
Query: 374 EKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFASNTS 553
L RI A ++ + + LV+EA+ E + +K LF++L+ + T+FASNTS
Sbjct: 67 T--TEALLARIQPA-ESLNSLADSGLVIEAVAEKLAIKQSLFRELEALCSPATLFASNTS 123
Query: 554 SLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXGKTCI 733
SLSI IA ++ + GLHFFNP P+M+L+ +V G +TS T T+ + GK +
Sbjct: 124 SLSITAIAGALQHPQRLAGLHFFNPAPLMKLVEIVSGLDTSTETVATLQRLTRQWGKQSV 183
Query: 734 TC 739
C
Sbjct: 184 LC 185
>UniRef50_Q5KYB5 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=6;
Bacillaceae|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Geobacillus kaustophilus
Length = 287
Score = 124 bits (298), Expect = 3e-27
Identities = 66/184 (35%), Positives = 109/184 (59%), Gaps = 1/184 (0%)
Frame = +2
Query: 185 IKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSR-VAKKMYKDN 361
I+ + V+G G+MG GIA V A G TLVD+ + L A+K I + + VA+ D+
Sbjct: 2 IERLVVVGSGVMGRGIAYVGAVGGFQTTLVDIKQEQLESAQKEIASIFEQGVARGKLTDS 61
Query: 362 PQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFA 541
++ ++ R++ + D A A + ADLV+EA+ E + +K ++F+ +D AP+ FA
Sbjct: 62 ERQ------EAEARLSYSLDLAAAVRDADLVIEAVPEKLELKKQVFETIDAHAPASCYFA 115
Query: 542 SNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXG 721
+NTS++S EI S KR ++ +HFFNPV M+L+ +++G ETS+ T + E + G
Sbjct: 116 TNTSTMSPTEIGSFTKRPERVIAMHFFNPVHKMKLVEIIRGLETSDETAQVAKEAAERMG 175
Query: 722 KTCI 733
K +
Sbjct: 176 KETV 179
>UniRef50_A0LPA1 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=1; Syntrophobacter fumaroxidans MPOB|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB)
Length = 287
Score = 123 bits (297), Expect = 4e-27
Identities = 67/186 (36%), Positives = 107/186 (57%)
Frame = +2
Query: 182 AIKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDN 361
A V V+G G MG+GIAQ+ AQ G V + D+S + KAK I L + ++ D
Sbjct: 2 ARNGVLVVGAGNMGAGIAQLCAQQGFEVVIADISLELSDKAKARIEKGLRKRVEQGKLDA 61
Query: 362 PQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFA 541
Q+ + L RI TA D A+ V+E+++E+I +K K+F +LD ++P TI A
Sbjct: 62 AQK-----DAILSRIQTAGDLGPAAVCR-FVIESVIEDIAIKRKVFAELDNLSPPETILA 115
Query: 542 SNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXG 721
+NT+SLSI+ +A +R ++ +HFFNP +M+L+ ++ G +TS T + E+ + G
Sbjct: 116 TNTTSLSISAMAEATRRPERVVQMHFFNPPVIMKLVEIMPGKKTSRETVEAAAEFARQLG 175
Query: 722 KTCITC 739
K + C
Sbjct: 176 KDPVVC 181
>UniRef50_Q9YBW6 Cluster: 3-hydroxyacyl-CoA
dehydrogenase/3-hydroxybutyryl-CoA dehydratase; n=19;
cellular organisms|Rep: 3-hydroxyacyl-CoA
dehydrogenase/3-hydroxybutyryl-CoA dehydratase -
Aeropyrum pernix
Length = 669
Score = 123 bits (296), Expect = 5e-27
Identities = 72/190 (37%), Positives = 108/190 (56%), Gaps = 3/190 (1%)
Frame = +2
Query: 173 MQSAIKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKK-M 349
M +K +TV+G G MG GIA+++A AG V L D++ D L A + I +L ++A+K
Sbjct: 1 MAGEVKTITVVGAGTMGHGIAELAAIAGFKVYLADINIDILNNALQRIRWSLEKLAEKGR 60
Query: 350 YKDNPQEVEKFVND--SLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAP 523
+++ + V + S+ + D A+A +D ++EAI E + +K +LF D A
Sbjct: 61 IRESVETVMSRITPIVSVRDGEYSEDLAKALSESDFMIEAIPEKLELKQQLFAFADKHAK 120
Query: 524 SHTIFASNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMME 703
I ASNTSSL I EIA+ R +K G+HFFNP +M L+ VVKG +TSE T ++
Sbjct: 121 ETAILASNTSSLPITEIAAATSRPEKVVGMHFFNPPVLMPLVEVVKGEKTSEETVAATVD 180
Query: 704 WGKSXGKTCI 733
K GK +
Sbjct: 181 LAKKMGKQTV 190
>UniRef50_Q7VRZ0 Cluster: Probable enoyl-CoA
hydratase/3-hydroxyacyl-CoA dehydrogenase, bifunctional
enzyme; n=3; Bordetella|Rep: Probable enoyl-CoA
hydratase/3-hydroxyacyl-CoA dehydrogenase, bifunctional
enzyme - Bordetella pertussis
Length = 705
Score = 122 bits (295), Expect = 7e-27
Identities = 65/182 (35%), Positives = 104/182 (57%)
Frame = +2
Query: 191 NVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNPQE 370
+ V+G G MG GIA A AG V +DV +L +A ++I + +A + +
Sbjct: 305 DAAVVGAGTMGRGIAIALADAGLRVRFIDVEQASLDRALEAIRAHYRSLAAR-----GRM 359
Query: 371 VEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFASNT 550
E D++ RI+ A+D +A+ AD+VVEA E++ +K +F+QLD + + A+NT
Sbjct: 360 TEAAARDAVARISPASDM-QAAAEADVVVEAAFEDLAIKQAIFRQLDSIVRPGAVLATNT 418
Query: 551 SSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXGKTC 730
S+L ++ IA+ +R G HFF+P VMRLL VV+G+ T+ T ++ G+ GK C
Sbjct: 419 STLDVDAIAAATRRPQDVVGTHFFSPANVMRLLEVVRGARTAPRTLGAVLALGRRMGKVC 478
Query: 731 IT 736
+T
Sbjct: 479 VT 480
>UniRef50_Q6MM12 Cluster: Fatty oxidation complex, alpha subunit;
n=1; Bdellovibrio bacteriovorus|Rep: Fatty oxidation
complex, alpha subunit - Bdellovibrio bacteriovorus
Length = 717
Score = 122 bits (295), Expect = 7e-27
Identities = 70/180 (38%), Positives = 103/180 (57%)
Frame = +2
Query: 185 IKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNP 364
+K + V+G G MG GIA V+A G V + D++ DAL K K ++ K+ D
Sbjct: 318 VKGLGVLGAGTMGGGIAYVAADKGIQVRMKDLNTDALGKGLKHASDLWMKLVKRKSIDKY 377
Query: 365 QEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFAS 544
Q +K + ++ +TD A K+ D+VVEAIVE++G+K K+ + G I A+
Sbjct: 378 QFQQK-----MDLVSVSTDYA-GFKNLDVVVEAIVEDMGIKQKVIGECAGQMRPDAIIAT 431
Query: 545 NTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXGK 724
NTSSLS+ E+A R + F G+HFFNPV M L+ V++G +TS+ T T+ E K GK
Sbjct: 432 NTSSLSVTEMAKGHPRPEYFAGMHFFNPVNKMPLIEVIRGEKTSDETIATIYELSKKMGK 491
>UniRef50_Q5V0V6 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2;
Halobacteriaceae|Rep: 3-hydroxybutyryl-CoA dehydrogenase
- Haloarcula marismortui (Halobacterium marismortui)
Length = 654
Score = 122 bits (294), Expect = 9e-27
Identities = 73/188 (38%), Positives = 104/188 (55%)
Frame = +2
Query: 170 AMQSAIKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKM 349
A Q I V V+G G MG GIA+V+A AG +V L D+ + I +L ++A+K
Sbjct: 3 ADQPEIATVAVLGAGTMGHGIAEVAAIAGYDVVLRDIDAAIVEDGYDEIEWSLEKLAEKG 62
Query: 350 YKDNPQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSH 529
D + D R+ T TD A ADLV+EA E + VK +F+ +D AP+
Sbjct: 63 RLDEDPD------DVAARVATTTDLEAAVSDADLVIEAGPEQLSVKQDIFESVDAAAPAD 116
Query: 530 TIFASNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWG 709
+ A+N+SSLSI EIA+ +R + GLHFFNP M L+ V+ G T++ T + E+
Sbjct: 117 ALLATNSSSLSITEIAAATERPESVLGLHFFNPPVKMDLVEVIYGKATTDETAQRGYEFI 176
Query: 710 KSXGKTCI 733
+S GKT I
Sbjct: 177 ESLGKTPI 184
>UniRef50_Q8FX64 Cluster: 3-hydroxyacyl-CoA dehydrogenase family
protein; n=10; Proteobacteria|Rep: 3-hydroxyacyl-CoA
dehydrogenase family protein - Brucella suis
Length = 509
Score = 122 bits (293), Expect = 1e-26
Identities = 65/183 (35%), Positives = 107/183 (58%)
Frame = +2
Query: 173 MQSAIKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMY 352
M+ +I ++ ++G G+MG+GIAQ++AQAG + D A A ++ + + L+++A+K
Sbjct: 1 MERSINHIAIVGAGVMGTGIAQIAAQAGLVTQIFDAREGAAAASRDRLASTLAKLAEKG- 59
Query: 353 KDNPQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHT 532
K + ++ + V+ RI + E + DLVVEAIVE + K LF +L+ V +
Sbjct: 60 KISAEDAQTAVS----RIEICSSIQELA-DCDLVVEAIVEKLDAKQALFLELEAVVSGNC 114
Query: 533 IFASNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGK 712
I A+NTSSLS+ IA V + ++ G HFFNPVP+M+++ V+ G T A ++ K
Sbjct: 115 ILATNTSSLSVTSIARVCRHPERVAGFHFFNPVPLMKVVEVIDGLTTDPAVGDALLVLAK 174
Query: 713 SXG 721
G
Sbjct: 175 RMG 177
>UniRef50_Q6KYW3 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Picrophilus torridus|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Picrophilus torridus
Length = 273
Score = 122 bits (293), Expect = 1e-26
Identities = 72/178 (40%), Positives = 108/178 (60%)
Frame = +2
Query: 194 VTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNPQEV 373
VTVIG G MGSGIA+V A V L DVSND L +K I +L + +K+ +
Sbjct: 3 VTVIGAGTMGSGIAEVFALNNHEVLLSDVSNDILNNGRKKIEASLEK-----FKEKGRI- 56
Query: 374 EKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFASNTS 553
K V D L +I+ TD ++ +DL +EA++E I VK + ++ S +I A+NTS
Sbjct: 57 -KSVEDVLEKISMNTDIN--AQESDLYIEAVLERIDVKRDVLSRIR----SDSIIATNTS 109
Query: 554 SLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXGKT 727
S+SI ++ V+ +KF G+HFFNP P+M L+ +V+G+ TS+ T K +++ +S GKT
Sbjct: 110 SISITYLSKFVRNPEKFIGMHFFNPPPIMSLIEIVRGNSTSDETTKRIVDISRSLGKT 167
>UniRef50_Q8YB80 Cluster: 3-HYDROXYBUTYRYL-COA DEHYDROGENASE; n=32;
Proteobacteria|Rep: 3-HYDROXYBUTYRYL-COA DEHYDROGENASE -
Brucella melitensis
Length = 565
Score = 121 bits (291), Expect = 2e-26
Identities = 65/188 (34%), Positives = 109/188 (57%)
Frame = +2
Query: 158 SNSSAMQSAIKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRV 337
+++ M+ +I ++ ++G G+MG+GIAQ++AQAG + D A A + + + L+++
Sbjct: 36 TDARTMERSINHIAIVGAGVMGTGIAQIAAQAGLVTQIFDAREGAAAASLDRLASTLAKL 95
Query: 338 AKKMYKDNPQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGV 517
A+K K + ++ + V+ RI + E + DLVVEAIVE + K LF +L+ V
Sbjct: 96 AEKG-KISAEDAQTAVS----RIEICSSIQELA-DCDLVVEAIVEKLDAKQALFLELEAV 149
Query: 518 APSHTIFASNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTM 697
+ I A+NTSSLS+ IA V + ++ G HFFNPVP+M+++ V+ G T A +
Sbjct: 150 VSGNCILATNTSSLSVTSIARVCRHPERVAGFHFFNPVPLMKVVEVIDGLTTDPAVGDAL 209
Query: 698 MEWGKSXG 721
+ K G
Sbjct: 210 LVLAKRMG 217
>UniRef50_A1IEK7 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Candidatus Desulfococcus oleovorans Hxd3|Rep:
3-hydroxybutyryl-CoA dehydrogenase - Candidatus
Desulfococcus oleovorans Hxd3
Length = 387
Score = 121 bits (291), Expect = 2e-26
Identities = 65/180 (36%), Positives = 103/180 (57%)
Frame = +2
Query: 185 IKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNP 364
IK + VIG G MG GIAQV AG V +VDV + L K + ++ + K K +
Sbjct: 6 IKKIAVIGSGAMGHGIAQVCIMAGYTVVMVDVKQEFLDNGMKKVKESMDFLVGKG-KLSA 64
Query: 365 QEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFAS 544
++ ++ +G+++T+ D A +V+EA+ E + +K K+F + AP+ + AS
Sbjct: 65 EDKDRM----MGQLSTSLDNKAAVADVQVVIEAVPEIMDLKKKVFADVSSAAPAEALLAS 120
Query: 545 NTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXGK 724
NTS++SI EIA+ V + ++F G+HFFNPV M+L+ V+ G +TS + E K GK
Sbjct: 121 NTSTMSITEIATAVTKPERFLGMHFFNPVNRMKLVEVIFGEKTSAENVDLLCELSKKIGK 180
>UniRef50_Q12D24 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
precursor; n=5; Burkholderiales|Rep:
3-hydroxybutyryl-CoA dehydrogenase precursor -
Polaromonas sp. (strain JS666 / ATCC BAA-500)
Length = 511
Score = 120 bits (289), Expect = 4e-26
Identities = 69/178 (38%), Positives = 101/178 (56%)
Frame = +2
Query: 200 VIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNPQEVEK 379
V+G G+MG GIAQV+AQAG V L D A A+AK + +L + K + +
Sbjct: 17 VVGAGVMGVGIAQVAAQAGHAVMLYDAREGAAAEAKTKLAKSLDALVAK-----GKLTAQ 71
Query: 380 FVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFASNTSSL 559
V+ +L RI A A+ A LV+EAIVE + VK LF+QL+ + + + A+NTSS+
Sbjct: 72 GVSQTLSRIEAIASLAAAAP-ARLVIEAIVEKLDVKRGLFQQLEAIVAADCVLATNTSSI 130
Query: 560 SINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXGKTCI 733
S+ IA+ ++ + G+HFFNPVP MRL+ VV G +T A + + GK +
Sbjct: 131 SVTAIANGLQHPARLVGMHFFNPVPQMRLVEVVSGLQTDPAVAALIFDLAGVWGKVAV 188
>UniRef50_A4YDR4 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor; n=2; Sulfolobaceae|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding precursor -
Metallosphaera sedula DSM 5348
Length = 334
Score = 120 bits (289), Expect = 4e-26
Identities = 76/178 (42%), Positives = 109/178 (61%), Gaps = 1/178 (0%)
Frame = +2
Query: 194 VTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNPQEV 373
V VIG G+MGSGI QV A AG VTL DV +AL KA + I +L ++ +K + ++V
Sbjct: 3 VFVIGSGVMGSGIGQVFAMAGHEVTLYDVKEEALKKAMEGIRWSLQKLQEK---GSVKDV 59
Query: 374 EKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAP-SHTIFASNT 550
E L RI T+ D +EA LV+EA+ E+I VK + L V+P + I ASNT
Sbjct: 60 ESV----LSRIFTSRDLSEARDH--LVIEAVFEDIKVKSDV---LGRVSPLTDEIIASNT 110
Query: 551 SSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXGK 724
SSL I E++ V+ ++F G+HFFNP +M+L+ V++G TSE ++ ++ KS GK
Sbjct: 111 SSLPITELSRAVRNPERFLGMHFFNPPVLMKLVEVIRGDNTSEERFREALDIVKSLGK 168
>UniRef50_A7D676 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=1; Halorubrum lacusprofundi ATCC
49239|Rep: 3-hydroxyacyl-CoA dehydrogenase, NAD-binding
- Halorubrum lacusprofundi ATCC 49239
Length = 676
Score = 119 bits (287), Expect = 6e-26
Identities = 66/181 (36%), Positives = 104/181 (57%)
Frame = +2
Query: 185 IKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNP 364
++ VTV+G G MG GIA+V+A AG +V L D+ + + I +L ++A+K D
Sbjct: 19 VQRVTVLGAGNMGHGIAEVAALAGYDVALRDIEEEFVQGGYDQIEWSLGKLAEK---DRI 75
Query: 365 QEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFAS 544
E E + +L R+ D ++ AD+VVE + E + +K ++ ++ AP +F +
Sbjct: 76 GEDE--ADAALDRVEAFVDLEDSLADADVVVEVVPEKMAIKKDVYDEVVEYAPEEAVFVT 133
Query: 545 NTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXGK 724
NTSSLSI E++ V R ++F G+HFFNP M L+ V+ G TSE T + + +S GK
Sbjct: 134 NTSSLSITELSEVTDRPERFCGMHFFNPPVRMDLVEVISGKHTSEDTLELIEGLAESMGK 193
Query: 725 T 727
T
Sbjct: 194 T 194
>UniRef50_Q5UWD9 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3;
cellular organisms|Rep: 3-hydroxyacyl-CoA dehydrogenase
- Haloarcula marismortui (Halobacterium marismortui)
Length = 295
Score = 119 bits (286), Expect = 9e-26
Identities = 68/180 (37%), Positives = 101/180 (56%), Gaps = 1/180 (0%)
Frame = +2
Query: 191 NVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSR-VAKKMYKDNPQ 367
+V ++G G MG GIAQVSA AG +V+L D+ D + +I +NL +A++ ++
Sbjct: 3 HVAILGAGTMGHGIAQVSAMAGHDVSLRDIEADIVDDGLTAIESNLEEGIAREKVTESTA 62
Query: 368 EVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFASN 547
E ++ R+ T EA ADLVVEA+ E + +KH+ ++ T+ ASN
Sbjct: 63 EA------TIDRLKGTTSLEEAVTGADLVVEAVPEEMAIKHETLTAVESHVDPATLIASN 116
Query: 548 TSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXGKT 727
TSSLS+ EIASV+ ++ GLHFFNPV +M L+ +V +TS T E+ KT
Sbjct: 117 TSSLSLTEIASVLDYPERAIGLHFFNPVHIMALVEIVVAEQTSAETIARAREFVNGIDKT 176
>UniRef50_Q13I86 Cluster: 3-hydroxybutyryl-CoA epimerase; n=11;
Burkholderia|Rep: 3-hydroxybutyryl-CoA epimerase -
Burkholderia xenovorans (strain LB400)
Length = 714
Score = 118 bits (285), Expect = 1e-25
Identities = 71/187 (37%), Positives = 105/187 (56%), Gaps = 1/187 (0%)
Frame = +2
Query: 176 QSAIKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYK 355
+ +++ + ++G G MG+GIAQVSA AG +V L+D + + SI L K
Sbjct: 310 KQSVRRLGIVGAGFMGAGIAQVSAAAGIDVVLLDRDLATAGRGRDSIAKALQAEVDK--- 366
Query: 356 DNPQEVEKFVNDS-LGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHT 532
+ + V D L RI A D + A + DLV+EA++E+ VK + + + P+H
Sbjct: 367 ---GRLREAVRDQILSRIEVAADHS-AFGNCDLVIEAVLEDFEVKASVTRATEAALPAHA 422
Query: 533 IFASNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGK 712
IFASNTS+L INE+AS R F GLHFF+PV M L+ V+ GS TS+ T +++ +
Sbjct: 423 IFASNTSALPINELASASARPQNFIGLHFFSPVSRMALVEVIVGSATSDETLARSLDYIQ 482
Query: 713 SXGKTCI 733
KT I
Sbjct: 483 QIHKTPI 489
>UniRef50_Q9RUA4 Cluster: Enoyl-CoA hydratase/3,2-trans-enoyl-CoA
isomerase/3-hydroxyacyl-CoA dehydrogenase; n=18;
Bacteria|Rep: Enoyl-CoA hydratase/3,2-trans-enoyl-CoA
isomerase/3-hydroxyacyl-CoA dehydrogenase - Deinococcus
radiodurans
Length = 708
Score = 118 bits (284), Expect = 2e-25
Identities = 71/180 (39%), Positives = 101/180 (56%)
Frame = +2
Query: 185 IKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNP 364
IK+ +IG G MG GIA G VT+V+ S +AL + I N AKK +
Sbjct: 307 IKSAGIIGAGTMGGGIAMNFLNVGIPVTIVETSQEALDRGLGVIRKNYENTAKKG-RMTQ 365
Query: 365 QEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFAS 544
+VEK +G + T T E AD+++EA+ EN+ VK +F +LD +A I AS
Sbjct: 366 DDVEK----RMGLL-TPTLKMEDLAGADIIIEAVFENMDVKKDIFTRLDKIAKPGAILAS 420
Query: 545 NTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXGK 724
NTS+L +NEIASV R ++ GLHFF+P VM+LL +V+ +TS++ T + K K
Sbjct: 421 NTSTLDVNEIASVTGRPEQVIGLHFFSPANVMKLLEIVRADKTSDSVLATSLALAKRIKK 480
>UniRef50_Q1ATL4 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Rubrobacter xylanophilus DSM 9941|Rep:
3-hydroxybutyryl-CoA dehydrogenase - Rubrobacter
xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 287
Score = 118 bits (284), Expect = 2e-25
Identities = 67/177 (37%), Positives = 100/177 (56%)
Frame = +2
Query: 194 VTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNPQEV 373
V V+G G MG+GI QV+A+AG V D S +AL KA++ + + L A++ +E
Sbjct: 5 VGVLGTGTMGAGIVQVAARAGYRVVACDASEEALGKARRYVRSGLESFARRGALSE-EEA 63
Query: 374 EKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFASNTS 553
E +LGR+ T A E ++ V+EAIVE +G K + F LD + P + +NTS
Sbjct: 64 EA----ALGRVRWTT-AMEELAGSEAVIEAIVERVGPKKEAFAALDALLPPDALLLTNTS 118
Query: 554 SLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXGK 724
S+SI E+AS R ++ G HFF P P+ + VV+G +TS+ T + + S GK
Sbjct: 119 SISITELASATGRPERVCGAHFFTPPPLREAVEVVRGEQTSDETVERVRRLLSSFGK 175
>UniRef50_Q12AF3 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=40; cellular organisms|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Polaromonas sp. (strain JS666 / ATCC BAA-500)
Length = 699
Score = 118 bits (284), Expect = 2e-25
Identities = 71/184 (38%), Positives = 105/184 (57%), Gaps = 1/184 (0%)
Frame = +2
Query: 185 IKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNL-SRVAKKMYKDN 361
IK++ VIG G MG GI+ AG V ++++ +AL + +I N S+V K K +
Sbjct: 297 IKSIAVIGAGTMGGGISMNFLNAGIPVKILEMKQEALDRGIATIRKNYESQVKKGKLKQD 356
Query: 362 PQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFA 541
E + ++T T + + K AD+V+EA+ E +GVK K+ K+LD V I A
Sbjct: 357 KYE------QRMSLLST-TLSYDDLKDADMVIEAVFEEMGVKEKVLKELDRVMKPGAILA 409
Query: 542 SNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXG 721
SNTS+L +N+IAS KR G HFF+P VM+LL VV+G +T++ T+M GK
Sbjct: 410 SNTSTLDMNQIASFTKRPQDVIGTHFFSPANVMKLLEVVRGEKTAKDVLATVMALGKKIK 469
Query: 722 KTCI 733
KT +
Sbjct: 470 KTAV 473
>UniRef50_Q9RZ10 Cluster: 3-hydroxyacyl-CoA dehydrogenase, putative;
n=11; Bacteria|Rep: 3-hydroxyacyl-CoA dehydrogenase,
putative - Deinococcus radiodurans
Length = 347
Score = 118 bits (283), Expect = 2e-25
Identities = 66/184 (35%), Positives = 106/184 (57%)
Frame = +2
Query: 182 AIKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDN 361
+IK VTV G G++GS IA +A G +V L D+++ A+AKA++++G +R + + D
Sbjct: 53 SIKTVTVCGSGVLGSQIAFQTAFHGFDVHLYDINDAAIAKARETLGKLQARYQQDLKVDA 112
Query: 362 PQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFA 541
Q D+ RI+ TD AEA K DLV+EAI EN+ +K K + QL VA +TIFA
Sbjct: 113 QQ-----TGDAFARISFFTDIAEAVKGVDLVIEAIPENMDIKRKFYNQLGEVADPNTIFA 167
Query: 542 SNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXG 721
+N+S+L ++ R +KF LHF N + +++ T +A + T++++ K G
Sbjct: 168 TNSSTLLPSQFMEETGRPEKFLALHFANEIWKFNTAEIMRTPRTDDAVFDTVVQFAKDIG 227
Query: 722 KTCI 733
+
Sbjct: 228 MVAL 231
>UniRef50_A4ALU9 Cluster: 3-hydroxyacyl-CoA dehydrogenase-like
protein; n=1; marine actinobacterium PHSC20C1|Rep:
3-hydroxyacyl-CoA dehydrogenase-like protein - marine
actinobacterium PHSC20C1
Length = 288
Score = 118 bits (283), Expect = 2e-25
Identities = 65/186 (34%), Positives = 101/186 (54%)
Frame = +2
Query: 182 AIKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDN 361
AI + V+G G MG GI Q++A G V + DV AL +A+ S+ T+L R +K +
Sbjct: 2 AITKLAVVGSGTMGHGIGQLAAMQGIAVRVFDVDEVALDRARASVATSLERFVRKETITD 61
Query: 362 PQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFA 541
Q ++ GR++ TD A + +EA+ E + +K K+F LD + A
Sbjct: 62 AQS-----HEIQGRMDWTTDLDAALVGVEAAIEAVPEVLALKQKVFTDLDERTGPEVMLA 116
Query: 542 SNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXG 721
+NTS LSI IAS K ++ G+HFFNP VMRL+ +++G+ TS+ + +++ G
Sbjct: 117 TNTSQLSITTIASSAKHPERVVGMHFFNPPVVMRLVEIIRGTMTSDEMLQRAIDFSDQLG 176
Query: 722 KTCITC 739
K I C
Sbjct: 177 KENIVC 182
>UniRef50_Q7WCB1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=4;
Bordetella|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Bordetella parapertussis
Length = 354
Score = 117 bits (282), Expect = 3e-25
Identities = 71/185 (38%), Positives = 102/185 (55%)
Frame = +2
Query: 170 AMQSAIKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKM 349
AM + I+N+ V+G G MGSGIA + A G +V L+D AL +A + I L A
Sbjct: 44 AMDNPIQNLAVVGAGAMGSGIAALFASKGFDVVLIDPMAGALTRAAQVIERQLGVYAPDA 103
Query: 350 YKDNPQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSH 529
Q + R++ +AA SA LV+EA+ E + +K +F +LD +
Sbjct: 104 IAPAMQRI---------RMDAGLEAA---CSAQLVIEAVPEKLALKRDIFARLDTLCDPQ 151
Query: 530 TIFASNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWG 709
IFA+NTS LSIN+IA V R+D+F G HFF P V+ L+ VV+ +TSE T +M
Sbjct: 152 AIFATNTSGLSINDIAQAVTRRDRFVGTHFFTPADVIPLVEVVRNDDTSEQTVARVMGML 211
Query: 710 KSXGK 724
++ GK
Sbjct: 212 RAGGK 216
>UniRef50_Q2B4D1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2;
Firmicutes|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Bacillus sp. NRRL B-14911
Length = 295
Score = 117 bits (282), Expect = 3e-25
Identities = 66/187 (35%), Positives = 104/187 (55%)
Frame = +2
Query: 173 MQSAIKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMY 352
M +KN+TV+G G MG IA + A G TL D+ AL +A++ + + + A K
Sbjct: 3 MALTVKNITVVGAGQMGHQIAMLCALGGFETTLHDMQEKALDQAQEKLRGIMDKWAAKGK 62
Query: 353 KDNPQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHT 532
+ Q + + R+ +D EA KSAD ++EA+VE + VK ++F L+ +AP H
Sbjct: 63 LPSEQ-----IEAAFSRLRCTSDFGEAVKSADFIIEAVVEKLEVKREVFSMLEEMAPPHA 117
Query: 533 IFASNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGK 712
IFA+N+S++ + +A+ R +K +HFF P VM + VV S TSE T +T ME
Sbjct: 118 IFATNSSTIVNSLLANAADRPEKTVNMHFFFPPLVMDCVEVVMSSRTSEETAETAMEVCN 177
Query: 713 SXGKTCI 733
+ +T +
Sbjct: 178 AINRTAV 184
>UniRef50_A6CP14 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Bacillus sp. SG-1|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Bacillus sp. SG-1
Length = 293
Score = 117 bits (282), Expect = 3e-25
Identities = 71/180 (39%), Positives = 103/180 (57%)
Frame = +2
Query: 194 VTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNPQEV 373
+ VIG G+MG GIA VSA G TLVDV L A+ + T++ + K + +E
Sbjct: 15 LVVIGSGVMGRGIAYVSAVGGFQTTLVDVEQRQLDSAQGEL-TSIFQKGVDRGKLSKEES 73
Query: 374 EKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFASNTS 553
D+ GR++ +TD A+A +SADLV+EA+ E +K +F+++D A FA+NTS
Sbjct: 74 ----TDAQGRLSFSTDMAKAVESADLVIEAVPEKTEIKKAVFEKIDEYAQESCYFATNTS 129
Query: 554 SLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXGKTCI 733
++S EIAS R K +HFFNPV M L+ +V+G ETS+ T + K GK +
Sbjct: 130 TMSPTEIASFTGRPKKVIAMHFFNPVHKMPLVEIVRGLETSDETTQFAENAAKRMGKETV 189
>UniRef50_Q5V357 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3;
Halobacteriaceae|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Haloarcula marismortui (Halobacterium marismortui)
Length = 669
Score = 117 bits (282), Expect = 3e-25
Identities = 59/181 (32%), Positives = 108/181 (59%)
Frame = +2
Query: 185 IKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNP 364
I + V+G G MG GI +V+A AG +V + D+ ++ + +I +L+++A++
Sbjct: 21 IDTIAVLGAGNMGHGITEVAALAGYDVRMRDIKDEFVEDGYDNIEWSLNKLAER-----D 75
Query: 365 QEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFAS 544
Q ++ + +L R+ D EA D+V+EA+ E + +K ++ +++ AP + IFA+
Sbjct: 76 QLTQEEADAALDRVTPLVDVEEAVSDVDVVIEAVPEKMEIKKDVYTEVEEHAPENAIFAT 135
Query: 545 NTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXGK 724
NTSSLSI E++ V +R ++F G+HFFNP M+L+ V+ G+ + + T + + + GK
Sbjct: 136 NTSSLSITELSEVTERPEQFCGMHFFNPPVRMQLVEVISGAHSGDDTLEAIEALAEDFGK 195
Query: 725 T 727
T
Sbjct: 196 T 196
>UniRef50_Q9ADL9 Cluster: Beta-hydroxybutyryl-CoA dehydrogenase;
n=7; Bacteria|Rep: Beta-hydroxybutyryl-CoA dehydrogenase
- Polyangium cellulosum (Sorangium cellulosum)
Length = 293
Score = 117 bits (281), Expect = 3e-25
Identities = 67/180 (37%), Positives = 98/180 (54%)
Frame = +2
Query: 194 VTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNPQEV 373
V V+G G+MG G+AQ AQ G +V LVDVS ALA+A+ I L V ++ +
Sbjct: 12 VGVVGAGVMGVGVAQSLAQTGHDVVLVDVSEAALARARMGIRNGLRAVTLFGSAEDKKRA 71
Query: 374 EKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFASNTS 553
L R+ TD + AD VVE + E +K +++ +L+GV IFA++TS
Sbjct: 72 GD-PKAVLERVAFTTDYGRLA-GADFVVENVTEKWDIKREVYARLEGVCRPEIIFAADTS 129
Query: 554 SLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXGKTCI 733
++SI I SV KR + G+HF NPVP+ ++ V++G TS T + GKTC+
Sbjct: 130 AISITRIGSVTKRPSQVVGMHFMNPVPLKPMVEVIRGFHTSPETLGAAKRFLAEMGKTCV 189
>UniRef50_A5V327 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=2; Alphaproteobacteria|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Sphingomonas wittichii RW1
Length = 748
Score = 117 bits (281), Expect = 3e-25
Identities = 67/180 (37%), Positives = 101/180 (56%)
Frame = +2
Query: 185 IKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNP 364
+ + +IG G MG GIA A AG V +VD + +AL + + + N + K+
Sbjct: 344 VASAAIIGAGTMGGGIAMCFAGAGIPVVIVDTTQEALDRGMERVRANYATSVKRGSISQE 403
Query: 365 QEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFAS 544
Q V+ L I ATD A A ADLV+EA+ E++ VK ++F L+ T+ AS
Sbjct: 404 Q-----VDKRLALITPATDRA-AVADADLVIEAVFEDMAVKKEIFSDLEKRVKPGTVLAS 457
Query: 545 NTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXGK 724
NTS+L ++EIA+ + R + F G+HFF+P VM+LL VV+ +++S T M G+ GK
Sbjct: 458 NTSALDVDEIAAALDRPEDFVGMHFFSPANVMKLLEVVQAAKSSPEAILTAMAVGRKIGK 517
>UniRef50_A5V4A1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
precursor; n=1; Sphingomonas wittichii RW1|Rep:
3-hydroxybutyryl-CoA dehydrogenase precursor -
Sphingomonas wittichii RW1
Length = 489
Score = 116 bits (279), Expect = 6e-25
Identities = 67/161 (41%), Positives = 97/161 (60%)
Frame = +2
Query: 194 VTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNPQEV 373
+ V+G G MG+GIA V+AQAG V ++D + AL + ++S+ +L+ + K+ D
Sbjct: 9 IAVVGAGTMGAGIALVAAQAGHAVRVIDTQDAALDRGRQSVARSLASLVKRGTID----- 63
Query: 374 EKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFASNTS 553
E RI +TD A+A+ +A L +EAIVE + VK LF+ L I ASNTS
Sbjct: 64 EAGAAAIAERIGWSTDVADAAPAA-LAIEAIVERMDVKTGLFETLARHVAPGAILASNTS 122
Query: 554 SLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETS 676
SLSI +AS V ++F GLHFFNPVP M+L+ ++ S T+
Sbjct: 123 SLSIEAMASAVPGPERFAGLHFFNPVPAMKLVELIPSSRTA 163
>UniRef50_A1SPQ6 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=3;
Actinomycetales|Rep: 3-hydroxybutyryl-CoA dehydrogenase
- Nocardioides sp. (strain BAA-499 / JS614)
Length = 287
Score = 116 bits (279), Expect = 6e-25
Identities = 71/180 (39%), Positives = 101/180 (56%)
Frame = +2
Query: 185 IKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNP 364
+++V V+G G MGS IA V A AG V L DV L +A + + ++R +K +
Sbjct: 1 MRSVLVVGAGAMGSQIAMVCALAGHQVCLHDVDPAMLERADRELRDRMARQVEKGRRTAD 60
Query: 365 QEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFAS 544
F + L R+ + AA A+ ADLV+EA+VE I VK +LF +LD + P TI AS
Sbjct: 61 DVTAAF--ERL-RVADSLAAAAAAADADLVIEAVVERIEVKSELFAELDRLCPPATILAS 117
Query: 545 NTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXGK 724
N+SS + +A+ R D+ LHFFNP VM + VV G ETS T + ++ +S GK
Sbjct: 118 NSSSFVPSRLAAATGRADRVCNLHFFNPALVMACVEVVPGPETSGQTVASCVDLVESLGK 177
>UniRef50_A0Z5J4 Cluster: Enoyl-CoA hydratase; n=2; unclassified
Gammaproteobacteria (miscellaneous)|Rep: Enoyl-CoA
hydratase - marine gamma proteobacterium HTCC2080
Length = 699
Score = 116 bits (279), Expect = 6e-25
Identities = 69/183 (37%), Positives = 103/183 (56%)
Frame = +2
Query: 185 IKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNP 364
I +V +IG G MG GIA AQAG VTLVD++++A+ + I N + KK
Sbjct: 293 IASVGIIGAGTMGGGIAMCFAQAGIAVTLVDMTDEAVKGGLEKIAKNYAISVKKGRLTVA 352
Query: 365 QEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFAS 544
Q + L I T++ + + + D+V+EA+ EN+ VK ++F +LD + + AS
Sbjct: 353 Q-----TDAILANITTSSSFDDLA-NVDMVIEAVFENLEVKKEVFGKLDVICKPGAVLAS 406
Query: 545 NTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXGK 724
NTS SI+ IA+ R + G+HFF+P VM+LL VVKG+ +S+ T M GK GK
Sbjct: 407 NTSYQSIDAIAAATSRPESVLGMHFFSPANVMKLLEVVKGASSSDIVIATAMAVGKKIGK 466
Query: 725 TCI 733
+
Sbjct: 467 VSV 469
>UniRef50_Q8FUX6 Cluster: 3-hydroxyacyl-CoA dehydrogenase family
protein; n=4; Brucella|Rep: 3-hydroxyacyl-CoA
dehydrogenase family protein - Brucella suis
Length = 501
Score = 116 bits (278), Expect = 8e-25
Identities = 71/175 (40%), Positives = 99/175 (56%), Gaps = 2/175 (1%)
Frame = +2
Query: 185 IKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNL-SRVAK-KMYKD 358
I V +IG G+MG+GIA+ A G +V L D D + AK ++ L SRV + K+ D
Sbjct: 6 IAKVAIIGSGVMGAGIAETMAAGGIDVLLFDQMADKASAAKLALSHRLQSRVERGKLGAD 65
Query: 359 NPQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIF 538
++ L RI E SADLVVEAIVEN+ VK L L+ + P +
Sbjct: 66 RAAQI-------LERIVPVQQLDEIV-SADLVVEAIVENLTVKKDLVAALEAILPRQAVI 117
Query: 539 ASNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMME 703
A+NTSSLS+ IA+ K ++ G HFFNPVP+MR++ V+KG+ T +A + E
Sbjct: 118 ATNTSSLSVTAIAASAKYPERIAGFHFFNPVPLMRVVEVIKGALTGDAVVDALKE 172
>UniRef50_Q2W2Y1 Cluster: Glyoxysomal fatty acid beta-oxidation
multifunctional protein MFP-a; n=3;
Magnetospirillum|Rep: Glyoxysomal fatty acid
beta-oxidation multifunctional protein MFP-a -
Magnetospirillum magneticum (strain AMB-1 / ATCC 700264)
Length = 703
Score = 115 bits (277), Expect = 1e-24
Identities = 68/181 (37%), Positives = 99/181 (54%)
Frame = +2
Query: 185 IKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNP 364
I+ V +IG G MG GIA A G VT++DVS++ L + I N R +
Sbjct: 294 IRKVGIIGAGTMGGGIAMCFANIGIPVTIIDVSDENLQRGLGVIRKNYERSVSRGSLTQE 353
Query: 365 QEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFAS 544
Q + +G ++ +TD A A K ADL +EA+ E + +K +F +LD V P+ I +
Sbjct: 354 Q-----LESRMGLLSASTDYA-ALKDADLAIEAVFEKMELKKDIFAKLDAVLPAGAILGT 407
Query: 545 NTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXGK 724
NTS+L I+EIA+ KR GLHFF+P VM LL +V+G +T+ T ++ K K
Sbjct: 408 NTSTLDIDEIANTTKRPADVIGLHFFSPANVMPLLEIVQGKQTAMDVLLTALDMAKLIKK 467
Query: 725 T 727
T
Sbjct: 468 T 468
>UniRef50_Q668V1 Cluster: Fatty acid oxidation complex subunit alpha
[Includes: Enoyl-CoA hydratase/3-hydroxybutyryl-CoA
epimerase (EC 4.2.1.17) (EC 5.1.2.3); 3-hydroxyacyl-CoA
dehydrogenase (EC 1.1.1.35)]; n=95; Proteobacteria|Rep:
Fatty acid oxidation complex subunit alpha [Includes:
Enoyl-CoA hydratase/3-hydroxybutyryl-CoA epimerase (EC
4.2.1.17) (EC 5.1.2.3); 3-hydroxyacyl-CoA dehydrogenase
(EC 1.1.1.35)] - Yersinia pseudotuberculosis
Length = 753
Score = 115 bits (277), Expect = 1e-24
Identities = 71/194 (36%), Positives = 112/194 (57%), Gaps = 2/194 (1%)
Frame = +2
Query: 158 SNSSAMQSAIKNVTVIGGGLMGSGIAQVSA-QAGQNVTLVDVSNDALAKAKKSIGTNLS- 331
+ S+A AI V V+GGGLMG GIA V+A +AG V + D++ + +A K L
Sbjct: 306 TGSAATARAIHRVGVLGGGLMGGGIANVTATRAGLPVRIKDINPQGINQALKYTWDALGK 365
Query: 332 RVAKKMYKDNPQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLD 511
RV K + Q+ + + I+ +TD + D+VVEA+ E++ +K ++ ++
Sbjct: 366 RVRSKRMRPTEQQRQMML------ISGSTDY-RGFERVDIVVEAVFEDLSLKQQMVADIE 418
Query: 512 GVAPSHTIFASNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYK 691
+HTIFASNTSSL I++IA++ +R ++ GLH+F+PV M L+ V+ +TSE T
Sbjct: 419 RFGAAHTIFASNTSSLPISQIAALAQRPEQVIGLHYFSPVDKMPLVEVIPHEKTSEETIA 478
Query: 692 TMMEWGKSXGKTCI 733
T + + GKT I
Sbjct: 479 TTVALARKQGKTAI 492
>UniRef50_Q5LVD0 Cluster: Enoyl-CoA
hydratase/isomerase/3-hydroxyacyl-CoA dehydrogenase;
n=6; Rhodobacterales|Rep: Enoyl-CoA
hydratase/isomerase/3-hydroxyacyl-CoA dehydrogenase -
Silicibacter pomeroyi
Length = 698
Score = 115 bits (276), Expect = 1e-24
Identities = 69/180 (38%), Positives = 101/180 (56%)
Frame = +2
Query: 194 VTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNPQEV 373
+ VIGGG MG+GIA + +G +VT+++++ +A AK I NLS K+
Sbjct: 292 IGVIGGGTMGAGIATAALLSGLSVTMLEMTPEAAEAAKGRIEGNLSGALKR----GKLTA 347
Query: 374 EKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFASNTS 553
++F N + + A D +A ADLV+EA+ E++ VK ++F +LD V + ASNTS
Sbjct: 348 QQFDNLTTKALTLAIDY-DALADADLVIEAVFEDMEVKKQVFTKLDAVCKPGAVLASNTS 406
Query: 554 SLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXGKTCI 733
L IN+IA+V R GLHFF+P VM+LL VV +T+ T GK GK +
Sbjct: 407 YLDINQIAAVTSRPQDVLGLHFFSPAHVMKLLEVVIADQTAPDVAATGFALGKRLGKVSV 466
>UniRef50_Q5NW50 Cluster: DitN-like 3-hydroxyacyl-CoA
dehydrogenase,possibly related to diterpenoid
metabolism; n=6; Proteobacteria|Rep: DitN-like
3-hydroxyacyl-CoA dehydrogenase,possibly related to
diterpenoid metabolism - Azoarcus sp. (strain EbN1)
(Aromatoleum aromaticum (strain EbN1))
Length = 299
Score = 114 bits (275), Expect = 2e-24
Identities = 67/185 (36%), Positives = 104/185 (56%)
Frame = +2
Query: 179 SAIKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKD 358
S ++ + V+G GLMG+GIA A +G + LVD + AL KA I + L K+ K
Sbjct: 2 SQMEKIIVVGAGLMGTGIAYSCAISGYRILLVDANPSALDKAVGQINS-LVAAGVKLGK- 59
Query: 359 NPQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIF 538
VE +L R+ A + + A L++E E I +K + + D + P I
Sbjct: 60 ---LVEAAGKAALERLEAAIELDGRASDAALLIETATEKIDIKLAIIGKADELLPPEAII 116
Query: 539 ASNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSX 718
ASNTS+LSI+E+A+ +R +F G+HFFNPV M+L+ +++G ET++AT + + +
Sbjct: 117 ASNTSALSISELAAATRRPTQFAGMHFFNPVHKMKLVELIRGIETTQATVERLKAVTAAL 176
Query: 719 GKTCI 733
GKT I
Sbjct: 177 GKTSI 181
>UniRef50_Q47M90 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=5;
root|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Thermobifida fusca (strain YX)
Length = 398
Score = 114 bits (275), Expect = 2e-24
Identities = 72/187 (38%), Positives = 105/187 (56%), Gaps = 2/187 (1%)
Frame = +2
Query: 173 MQSAIKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSR-VAK-K 346
M I V V+G G MG+GI +V A+AG VT V++ + AL + + + +L++ VAK K
Sbjct: 1 MVEEINKVGVVGLGTMGAGIVEVFARAGFTVTGVEIDDAALERGRTHLEKSLAKAVAKGK 60
Query: 347 MYKDNPQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPS 526
+ +D + + LGR+ T T + + A L VEA+ E + +K +F LD + P
Sbjct: 61 LTEDEQRAI-------LGRV-TFTTSRDDLADAHLAVEAVPERLDIKRSVFADLDRILPP 112
Query: 527 HTIFASNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEW 706
I A+NTSSLS+ EIA++ R K GLHFFNP PVMRL+ +V T +T +
Sbjct: 113 AAILATNTSSLSVTEIAALTSRPGKVIGLHFFNPAPVMRLVEIVTTVVTEPHVRETATQV 172
Query: 707 GKSXGKT 727
GKT
Sbjct: 173 VTRLGKT 179
>UniRef50_O69856 Cluster: Fatty acid oxidation complex
alpha-subunit; n=6; Actinobacteria (class)|Rep: Fatty
acid oxidation complex alpha-subunit - Streptomyces
coelicolor
Length = 709
Score = 114 bits (275), Expect = 2e-24
Identities = 64/184 (34%), Positives = 101/184 (54%), Gaps = 1/184 (0%)
Frame = +2
Query: 185 IKNVTVIGGGLMGSGIAQVSAQAGQ-NVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDN 361
+ V V+G GLM S +A + + + V L D+ + + K +G + + K + K
Sbjct: 338 VTKVGVVGAGLMASQLALLFLRRLEVPVVLTDIDQE---RVDKGVGYVHAEIDKLLGKGR 394
Query: 362 PQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFA 541
+ + N + D AE AD V+EA+ E +GVK K+F +++ VAP+H I A
Sbjct: 395 VNQDK--ANRLKALVTGVLDKAEGFADADFVIEAVFEEMGVKQKVFAEVEAVAPAHAILA 452
Query: 542 SNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXG 721
+NTSSLS++E+AS +K ++ G HFFNPV ++ LL +V+G +T EA T K
Sbjct: 453 TNTSSLSVSEMASKLKHPERVVGFHFFNPVAILPLLEIVRGEQTDEAALATAFGVAKKLK 512
Query: 722 KTCI 733
KT +
Sbjct: 513 KTAV 516
>UniRef50_O29815 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Archaeoglobus fulgidus|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Archaeoglobus fulgidus
Length = 304
Score = 114 bits (275), Expect = 2e-24
Identities = 64/182 (35%), Positives = 104/182 (57%)
Frame = +2
Query: 188 KNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNPQ 367
+ + V+G GLMG+ I Q AQ G V +DVS + L K ++I + + + K
Sbjct: 3 EKIGVVGFGLMGTQITQFFAQQGLEVVAIDVSEERLRKGMEAIKAGRFGLQRLVEKGKIT 62
Query: 368 EVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFASN 547
E E +N L RI+T+T + A K DLV+EA+ E++ +K K+ +++D V + + SN
Sbjct: 63 EEE--MNAVLSRISTSTSHS-ALKDCDLVIEAVFEDVNLKLKVLREIDAVTDA--VIGSN 117
Query: 548 TSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXGKT 727
TSS+SI +++S V ++F G+HFFNP + +L+ +VKG + E + +W GK
Sbjct: 118 TSSISITKLSSAVSNPERFLGIHFFNPAQIQKLVELVKGLLSDEKLVNGIRDWFLKLGKV 177
Query: 728 CI 733
I
Sbjct: 178 PI 179
>UniRef50_A5WEP3 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=7; Proteobacteria|Rep: 3-hydroxyacyl-CoA
dehydrogenase, NAD-binding - Psychrobacter sp. PRwf-1
Length = 723
Score = 114 bits (274), Expect = 2e-24
Identities = 67/186 (36%), Positives = 103/186 (55%)
Frame = +2
Query: 176 QSAIKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYK 355
+S + V ++G G+MG+GIA VSA+AG +V L+D S +A K K L + +
Sbjct: 319 RSKVSKVGILGAGMMGAGIAYVSAKAGIDVVLLDTSIEAAEKGKDYSSKLLDKAIAR--- 375
Query: 356 DNPQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTI 535
+ E+ L +INT T A + + DL++EA+ E+I +K + + V I
Sbjct: 376 --GRSTEQKKQALLDKINTTT-AYDDLEDCDLIIEAVFEDIDIKAACTRNTEAVIAETAI 432
Query: 536 FASNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKS 715
+ASNTS+L I E+A KR ++F GLHFF+PV M L+ ++ G ET +AT ++
Sbjct: 433 YASNTSTLPITELAKASKRPNQFIGLHFFSPVDKMPLVEIIVGEETDDATLAKGFDYVGQ 492
Query: 716 XGKTCI 733
KT I
Sbjct: 493 IAKTPI 498
>UniRef50_A4FGV2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2;
Actinomycetales|Rep: 3-hydroxybutyryl-CoA dehydrogenase
- Saccharopolyspora erythraea (strain NRRL 23338)
Length = 517
Score = 114 bits (274), Expect = 2e-24
Identities = 63/176 (35%), Positives = 99/176 (56%)
Frame = +2
Query: 194 VTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNPQEV 373
V VIG G+MG GIAQ++A AG V L D +A++ A +G ++ K + + +E
Sbjct: 11 VRVIGTGVMGRGIAQLAAAAGLTVELADARQEAVSAAVDHVGEMFGKLVGKG-RMSAEEA 69
Query: 374 EKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFASNTS 553
+ + R+ D + S DLVVEA+ E++ K +LF L+ V P H + A+NTS
Sbjct: 70 DA----ATARLRPVGDPLAPADSCDLVVEAVREDLDTKRELFAGLEEVCPRHAVLATNTS 125
Query: 554 SLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXG 721
SLS+ I + + + GLHFFNPVP+M+L+ V+ G+ T + ++E + G
Sbjct: 126 SLSVTAIGAALADPSRLIGLHFFNPVPLMKLVEVIPGARTRQDLSADLVELVRRLG 181
>UniRef50_Q9XA30 Cluster: Putative 3-Hydroxyacyl-CoA dehydrogenase;
n=2; Streptomyces|Rep: Putative 3-Hydroxyacyl-CoA
dehydrogenase - Streptomyces coelicolor
Length = 504
Score = 113 bits (273), Expect = 3e-24
Identities = 68/182 (37%), Positives = 99/182 (54%)
Frame = +2
Query: 194 VTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNPQEV 373
V V+G G MG GIAQV+ AG V L D + +A +IG L R+ +K D
Sbjct: 10 VAVVGTGTMGQGIAQVALVAGHPVRLYDAVDGRAREAADAIGARLDRLVEK---DRLTGA 66
Query: 374 EKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFASNTS 553
E+ + + R+ A E + A LVVEA+VE + VK +LF+ L+ V + A+NTS
Sbjct: 67 ER--DAARARLVPAGTLGELADCA-LVVEAVVERLDVKQELFRALEDVVGDDCLLATNTS 123
Query: 554 SLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXGKTCI 733
SLS+ + ++ +F GLHFFNP P++ L+ VV G T A+ E ++ GKT +
Sbjct: 124 SLSVTAVGGALRVPGRFVGLHFFNPAPLLPLVEVVSGFATDPASATRAYETARAWGKTPV 183
Query: 734 TC 739
C
Sbjct: 184 AC 185
>UniRef50_A3ZYI9 Cluster: Fatty oxidation complex, alpha subunit
FadB; n=1; Blastopirellula marina DSM 3645|Rep: Fatty
oxidation complex, alpha subunit FadB - Blastopirellula
marina DSM 3645
Length = 724
Score = 113 bits (272), Expect = 4e-24
Identities = 64/183 (34%), Positives = 110/183 (60%)
Frame = +2
Query: 176 QSAIKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYK 355
++ I++V+VIG G+MG+GIA S + G TL D + +AL ++ + L A +
Sbjct: 314 KTKIESVSVIGAGIMGAGIAAASIRRGILTTLSDANAEAL---RRGVAGVLEEAAYD--R 368
Query: 356 DNPQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTI 535
D ++ + +N + +E + S LV+EAIVEN+ VK K++ +L+ I
Sbjct: 369 DAGKKTIAKAVEGAAMLNASISDSEVAASK-LVIEAIVENLEVKRKIYARLEPQLADDAI 427
Query: 536 FASNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKS 715
ASNTS+L I ++A+ + + ++F G+HFFNPV M+L+ V++G++TS+AT + + + K
Sbjct: 428 LASNTSTLPITQLAANLAKPERFVGIHFFNPVRKMKLVEVIRGAQTSDATVASAVAFAKR 487
Query: 716 XGK 724
GK
Sbjct: 488 LGK 490
>UniRef50_A1SXV8 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=2; Psychromonas|Rep: 3-hydroxyacyl-CoA
dehydrogenase, NAD-binding - Psychromonas ingrahamii
(strain 37)
Length = 724
Score = 113 bits (272), Expect = 4e-24
Identities = 66/183 (36%), Positives = 104/183 (56%)
Frame = +2
Query: 185 IKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNP 364
I V+G G+MG GIA + ++ V L D+ DA++K ++ ++ KK++K N
Sbjct: 324 INQAAVLGAGVMGGGIAWLFSKNEIPVRLKDIEWDAVSKGYQTAALYYGQL-KKVHKINE 382
Query: 365 QEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFAS 544
++ +N G +N K DLVVEA+ EN+ VK + ++++ I AS
Sbjct: 383 NKIRVKMNYIAGTVNY-----NGFKRIDLVVEAVSENLEVKKTVLEEVEAQLSKQAILAS 437
Query: 545 NTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXGK 724
NTSSLSI E+A ++R + F G+HFFNPV M L+ ++ G +TS+ T T+++ K GK
Sbjct: 438 NTSSLSITEMAVNLQRPENFIGMHFFNPVNRMPLVEIIPGEKTSQQTIVTLVKLAKKAGK 497
Query: 725 TCI 733
T I
Sbjct: 498 TPI 500
>UniRef50_UPI0000E4974C Cluster: PREDICTED: hypothetical protein;
n=3; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 953
Score = 112 bits (270), Expect = 7e-24
Identities = 71/194 (36%), Positives = 100/194 (51%), Gaps = 2/194 (1%)
Frame = +2
Query: 158 SNSSAMQSAIKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRV 337
S +A +K+ VIG G MG GI AG L + + L K K + L+
Sbjct: 317 SYKTAKGQEVKSAAVIGAGTMGVGITMSMVMAGIPTYLTEQNQQYLDKGLKMVQGILAHW 376
Query: 338 AK--KMYKDNPQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLD 511
K +M + Q++ V +L T D K D+VVEA+ EN+ +K ++ K LD
Sbjct: 377 VKQGRMSEAKAQQIFSLVRPTL----TYDDL----KDVDVVVEAVFENMALKKEILKTLD 428
Query: 512 GVAPSHTIFASNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYK 691
GV I ASNTS+L I+E+AS R DK G+HFF+P +M+LL V+G +TS T
Sbjct: 429 GVCKPSAILASNTSTLDIDEMASATTRPDKVMGMHFFSPAHIMKLLENVRGKDTSPETMA 488
Query: 692 TMMEWGKSXGKTCI 733
T M+ GK K +
Sbjct: 489 TAMDLGKRMKKISV 502
>UniRef50_Q1D1F2 Cluster: Fatty oxidation complex, alpha subunit
FadJ; n=2; Cystobacterineae|Rep: Fatty oxidation
complex, alpha subunit FadJ - Myxococcus xanthus (strain
DK 1622)
Length = 746
Score = 112 bits (270), Expect = 7e-24
Identities = 68/193 (35%), Positives = 104/193 (53%), Gaps = 1/193 (0%)
Frame = +2
Query: 158 SNSSAMQSAIKNVTVIGGGLMGSGIAQV-SAQAGQNVTLVDVSNDALAKAKKSIGTNLSR 334
SN A +K V V+GGGLMG GIA V S G V + D + + +A K + + L
Sbjct: 340 SNPDAKPREVKKVAVLGGGLMGGGIAYVTSVLQGVPVRVKDKDDAGVGRAMKQVQSILDE 399
Query: 335 VAKKMYKDNPQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDG 514
K+ + K + TD + KSADLV+EA+ E++ +KH++ +++
Sbjct: 400 RVKRRSLTRREATAKSA-----LVTAGTDYS-GFKSADLVIEAVFEDLKLKHRIIAEVEA 453
Query: 515 VAPSHTIFASNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKT 694
V TIFASNTSS+ I E+A +R + G+H+F+PV M LL ++ + T++ T
Sbjct: 454 VTGDQTIFASNTSSIPITELAKGSRRPAQVIGMHYFSPVHKMPLLEIITHAGTADWVTAT 513
Query: 695 MMEWGKSXGKTCI 733
+E G+ GKT I
Sbjct: 514 CVEVGRKQGKTVI 526
>UniRef50_Q11E55 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor; n=1; Mesorhizobium sp. BNC1|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding precursor -
Mesorhizobium sp. (strain BNC1)
Length = 506
Score = 112 bits (270), Expect = 7e-24
Identities = 65/181 (35%), Positives = 104/181 (57%), Gaps = 1/181 (0%)
Frame = +2
Query: 185 IKNVTVIG-GGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDN 361
IK V + G GG MG+GIA V+A+AG D + +AL ++SIG K + K
Sbjct: 4 IKKVAICGAGGTMGAGIAMVAARAGFQTICFDQNGEAL---RRSIGAAEDFFRKSVEKGR 60
Query: 362 PQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFA 541
+ +++L R+ T+T+ + + DL++EAI EN+ K +LF+ L+ + TI A
Sbjct: 61 MSPDD--CDNALSRMTTSTNLKDLA-DCDLIIEAIFENLEAKQQLFRSLNEICKPETILA 117
Query: 542 SNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXG 721
SNTS+LSI +IAS R+D+ G HF P +M+L+ + +G TS+ + + W K+ G
Sbjct: 118 SNTSTLSITQIASGCGREDRVVGTHFCLPAQLMKLVEMSRGINTSDGVFSAALAWTKAAG 177
Query: 722 K 724
+
Sbjct: 178 Q 178
>UniRef50_Q9HRI4 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=7;
cellular organisms|Rep: 3-hydroxyacyl-CoA dehydrogenase
- Halobacterium salinarium (Halobacterium halobium)
Length = 286
Score = 112 bits (269), Expect = 1e-23
Identities = 63/162 (38%), Positives = 92/162 (56%)
Frame = +2
Query: 188 KNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNPQ 367
+ + V+G G MG+GIAQV+A AG V + D+ + + SI ++L R + N
Sbjct: 8 ETIGVVGAGTMGAGIAQVAATAGYTVVMRDIEQEYVDAGFDSIESSLDR-----FVSNDD 62
Query: 368 EVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFASN 547
E + + RI TD AE + D+V+EA VE++ +K +F+ LD P + A+N
Sbjct: 63 LSEADADAIVDRITGTTDLAELA-DCDVVIEAAVEDMEIKQDIFRDLDDALPEDVVLATN 121
Query: 548 TSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSET 673
TS+LSI IASV R + GLHF NPVP+M + VV G +T
Sbjct: 122 TSTLSITTIASVTDRASRVVGLHFMNPVPIMTGVEVVVGEKT 163
>UniRef50_Q397D0 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=31;
Proteobacteria|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Burkholderia sp. (strain 383) (Burkholderia cepacia
(strain ATCC 17760/ NCIB 9086 / R18194))
Length = 518
Score = 111 bits (268), Expect = 1e-23
Identities = 72/189 (38%), Positives = 104/189 (55%), Gaps = 5/189 (2%)
Frame = +2
Query: 161 NSSAMQSAIKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVA 340
NS A+ ++ V VIG G MG+GIAQV+A AG V L D++ A KA I +R+A
Sbjct: 10 NSGALAPSVV-VGVIGAGAMGAGIAQVAAAAGHTVLLYDLNEAACDKALAGIRAQFARLA 68
Query: 341 KKMYKDNPQEVEKFVNDSLG-RINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGV 517
+K +E D+ G RI + A+ + +A L+VEA E + VK ++F L+
Sbjct: 69 EK------GRLEPAQADAAGARIRAVRELADFAGAA-LIVEAAAERLDVKREIFATLERH 121
Query: 518 APSHTIFASNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKG----SETSEAT 685
+ A+NTSS+SI IA+ ++ + GLHFFNP P+M L+ VV G E ++
Sbjct: 122 VDDACLLATNTSSISITSIAAGLRVPQRVAGLHFFNPAPLMALVEVVSGLATAPEVAQVL 181
Query: 686 YKTMMEWGK 712
Y T WGK
Sbjct: 182 YATAAAWGK 190
>UniRef50_A6GC68 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Plesiocystis pacifica SIR-1|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Plesiocystis pacifica SIR-1
Length = 733
Score = 111 bits (268), Expect = 1e-23
Identities = 58/176 (32%), Positives = 101/176 (57%)
Frame = +2
Query: 179 SAIKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKD 358
+ I+ V ++G G+MG+G+A + A AG V L D++ +AL K L + + +
Sbjct: 330 AGIERVAILGAGMMGAGLAYICADAGYQVVLKDINQEALDKGVAHFEAQLRKRKRHLDDA 389
Query: 359 NPQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIF 538
Q + + SL ++ +D + DL++EA+ EN+ +KH++ ++ + + I+
Sbjct: 390 GRQAIRDRLTPSL-ELSALSD----NGGTDLIIEAVFENLDLKHRVTRETEPTLSADGIW 444
Query: 539 ASNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEW 706
ASNTS++ I ++A V D+F GLH+F+PV VM LL +V G ETSE T +++
Sbjct: 445 ASNTSAIPIGDLAKVSAHADRFIGLHYFSPVEVMPLLEIVVGPETSERTLARCLDF 500
>UniRef50_O17761 Cluster: Putative uncharacterized protein ech-8;
n=4; Caenorhabditis|Rep: Putative uncharacterized
protein ech-8 - Caenorhabditis elegans
Length = 437
Score = 111 bits (268), Expect = 1e-23
Identities = 67/180 (37%), Positives = 101/180 (56%)
Frame = +2
Query: 185 IKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNP 364
IK+V VIGGG MG GIA +G LV+V+N A K + R K + N
Sbjct: 39 IKSVAVIGGGTMGRGIAIAFCLSGFETYLVEVNNKAAEFCKNELEITYKR-EKAFRRLND 97
Query: 365 QEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFAS 544
+VEK + + TD + + + DL+VEA+ E++ +K +LF +LD + IF +
Sbjct: 98 SKVEKLRKN----LQITTDFQKLN-NCDLIVEAVFEDMKLKKELFTKLDKICKPSCIFGT 152
Query: 545 NTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXGK 724
NTSSL +NE++SV++ K G+HFFNP ++R++ V+ GS+TS T E +S K
Sbjct: 153 NTSSLDLNEMSSVLRDPTKVVGIHFFNPANLIRMVEVIYGSKTSSKAVATAFEACRSIKK 212
>UniRef50_Q2S2J8 Cluster: Fatty oxidation complex, alpha subunit;
n=2; Bacteria|Rep: Fatty oxidation complex, alpha
subunit - Salinibacter ruber (strain DSM 13855)
Length = 719
Score = 111 bits (267), Expect = 2e-23
Identities = 67/184 (36%), Positives = 105/184 (57%), Gaps = 1/184 (0%)
Frame = +2
Query: 185 IKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNP 364
+ V V+G GLMGSGIAQVSAQ G +V L D S A+ KK+I + ++ +++
Sbjct: 318 VDTVGVLGAGLMGSGIAQVSAQNGLDVVLTDQSLALAAEGKKAIWSAVTE------QEDK 371
Query: 365 QEVEKFVNDSL-GRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFA 541
+ F D + R+ D A ++AD+V+EA+ E++ +KH + +++ V + T+ A
Sbjct: 372 GIINTFTRDQIVERVAPTADYAPL-QAADVVIEAVPEDLSIKHAVLSEVETVVDADTVLA 430
Query: 542 SNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXG 721
SNTS+L I+ IA V + G+H+F+PVP + LL +V ETS+ T G +
Sbjct: 431 SNTSALPISTIAEGVDDPSRVLGMHYFSPVPDIPLLEIVVTEETSDEALATAYAAGLAQD 490
Query: 722 KTCI 733
KT I
Sbjct: 491 KTVI 494
>UniRef50_Q6V1N6 Cluster: PlmT8; n=1; Streptomyces sp. HK803|Rep:
PlmT8 - Streptomyces sp. HK803
Length = 571
Score = 111 bits (267), Expect = 2e-23
Identities = 66/184 (35%), Positives = 103/184 (55%)
Frame = +2
Query: 188 KNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNPQ 367
+ + V+G G M +GIAQ A+AG TLV S +A ++ +L+R ++ + P+
Sbjct: 291 RRIGVVGSGTMATGIAQACARAGYPTTLVARSEVRAKEALATVENSLNRAVQRG-RLTPE 349
Query: 368 EVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFASN 547
++ + +SL T EA + DLVVEA+VE+I VK +F++LD V + T+ A++
Sbjct: 350 QLTSSM-ESL----TGVSRLEAVAACDLVVEAVVEDIDVKRTVFRELDAVCGAQTVLATS 404
Query: 548 TSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXGKT 727
TSSL + E A R + G+HFFNP PVM+L+ VV+ + TS T + GK
Sbjct: 405 TSSLPVIECAMATGRPEAVVGMHFFNPAPVMKLVEVVRTALTSRETLGVAHATATALGKR 464
Query: 728 CITC 739
+ C
Sbjct: 465 PVGC 468
Score = 49.6 bits (113), Expect = 8e-05
Identities = 45/155 (29%), Positives = 67/155 (43%)
Frame = +2
Query: 173 MQSAIKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMY 352
M + VIG G GS +A ++A++G+ V VD AL A G L+
Sbjct: 1 MAKRFSTIAVIGLGTTGSVLASMAARSGRRVIAVDTDASALDLA----GARLTDTGP--- 53
Query: 353 KDNPQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHT 532
G I+ T +A+ SADLV+EA+ E + K +L
Sbjct: 54 ---------------GTIDLTTRSADIV-SADLVIEAVPERMKTKCELLSHAHNACAPGA 97
Query: 533 IFASNTSSLSINEIASVVKRKDKFGGLHFFNPVPV 637
+FA+ TS L++ +IA R + GLH F P+
Sbjct: 98 VFATTTSGLAVTDIAFGSGRPCRTVGLHLFPQGPM 132
>UniRef50_A6X670 Cluster: 3-hydroxyacyl-CoA dehydrogenase
NAD-binding; n=1; Ochrobactrum anthropi ATCC 49188|Rep:
3-hydroxyacyl-CoA dehydrogenase NAD-binding -
Ochrobactrum anthropi (strain ATCC 49188 / DSM 6882 /
NCTC 12168)
Length = 659
Score = 111 bits (267), Expect = 2e-23
Identities = 66/184 (35%), Positives = 102/184 (55%)
Frame = +2
Query: 182 AIKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDN 361
A+ + + G GLMGSGIA S AG V + + +A AK I + + D
Sbjct: 293 ALSTIGIAGTGLMGSGIAVASLAAGYTVIGYETTAEAAAKGHARITDMIQKAV-----DT 347
Query: 362 PQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFA 541
+ + + +++ + D A A ADLV+EA+ ++ VK LF++LD + P TI A
Sbjct: 348 GRLSTEAADAQRSKLSVSADMA-ALADADLVIEAVFDDFTVKASLFRELDALLPPATILA 406
Query: 542 SNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXG 721
+NTS L+ +E+A+V R D+ GLHFF+P +MRLL VV+ +ETS+ T T + + +
Sbjct: 407 TNTSYLNPDELAAVTNRTDRVLGLHFFSPANIMRLLEVVRCAETSDETLATGIAFARKIK 466
Query: 722 KTCI 733
K I
Sbjct: 467 KLSI 470
>UniRef50_Q39TJ4 Cluster: 3-hydroxyacyl-CoA dehydrogenase-like; n=1;
Geobacter metallireducens GS-15|Rep: 3-hydroxyacyl-CoA
dehydrogenase-like - Geobacter metallireducens (strain
GS-15 / ATCC 53774 / DSM 7210)
Length = 290
Score = 111 bits (266), Expect = 2e-23
Identities = 71/183 (38%), Positives = 103/183 (56%), Gaps = 3/183 (1%)
Frame = +2
Query: 185 IKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNP 364
IK V ++G G+MGS IA A AG +V L +VS D A + I +L++ ++K
Sbjct: 4 IKKVAILGAGMMGSDIALSCALAGYDVLLKEVSLDLAAAGVERIRGSLAKWSEKGRLAVD 63
Query: 365 QEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFAS 544
E +K ++ RI T D DLV+EAI E++ VK + F+QL+ V I AS
Sbjct: 64 AEQQK---SAVARI-TPVDNFSGFGDVDLVIEAIFEDLDVKSQNFRQLEEVCKPSCIIAS 119
Query: 545 NTSSLSINEIA---SVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKS 715
NTSSL I ++ S +RK +F G+HFF+P +M+L+ VV G +TS T +T + S
Sbjct: 120 NTSSLPITKLGACFSSAERKSRFVGMHFFSPAAIMKLVEVVNGEDTSAETVETACAFCTS 179
Query: 716 XGK 724
GK
Sbjct: 180 IGK 182
>UniRef50_A7PEM6 Cluster: Chromosome chr11 scaffold_13, whole genome
shotgun sequence; n=3; core eudicotyledons|Rep:
Chromosome chr11 scaffold_13, whole genome shotgun
sequence - Vitis vinifera (Grape)
Length = 724
Score = 110 bits (265), Expect = 3e-23
Identities = 66/193 (34%), Positives = 103/193 (53%)
Frame = +2
Query: 146 VRNFSNSSAMQSAIKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTN 325
V N ++ +K V VIGGGLMGSGIA + V L +V+++ L K K+I N
Sbjct: 295 VPNVTDIGLKPRNVKKVAVIGGGLMGSGIATALITSNIYVVLKEVNSEYLLKGIKTIEAN 354
Query: 326 LSRVAKKMYKDNPQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQ 505
+ + K K + K +L + D +E K D+V+EA++ENI +K K+F +
Sbjct: 355 VRGLVTKG-KLTQDKARK----ALSMLKGVLDYSEF-KDIDMVIEAVIENISLKQKIFSE 408
Query: 506 LDGVAPSHTIFASNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEAT 685
++ + H I A+NTS++ +N + +D+ G HFF+P VM LL VV+ +TS
Sbjct: 409 IEKICSPHCILATNTSTIDLNLVGEKTSSQDRIIGAHFFSPAHVMPLLEVVRTEKTSAQV 468
Query: 686 YKTMMEWGKSXGK 724
+M GK+ K
Sbjct: 469 ILDLMTVGKAIKK 481
>UniRef50_Q5P039 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3;
Proteobacteria|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Azoarcus sp. (strain EbN1) (Aromatoleum aromaticum
(strain EbN1))
Length = 443
Score = 109 bits (263), Expect = 5e-23
Identities = 65/183 (35%), Positives = 93/183 (50%)
Frame = +2
Query: 185 IKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNP 364
I+ V VIG G MG GIA A G VT+ D AL + + + N + D
Sbjct: 41 IRRVGVIGAGTMGGGIAMSFANVGIPVTVCDTDGAALERGLERVRRNYEFSVARGRLDAA 100
Query: 365 QEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFAS 544
+ L I A D + K ADLV+EA+ E++ +K +F++LD + I A+
Sbjct: 101 TMAAR-----LALIRAAVDLQDL-KDADLVIEAVFEDMALKQDIFRKLDAIVHPDAILAT 154
Query: 545 NTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXGK 724
NTS L I+EIA V +R G HFF+P V +LL VV+G+ T+ T+M G+ GK
Sbjct: 155 NTSGLDIDEIAVVTRRPQDVVGAHFFSPAHVQKLLEVVRGARTAPEVIATLMSLGRRMGK 214
Query: 725 TCI 733
+
Sbjct: 215 VSV 217
>UniRef50_A1VP66 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=1; Polaromonas naphthalenivorans CJ2|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Polaromonas naphthalenivorans (strain CJ2)
Length = 686
Score = 109 bits (263), Expect = 5e-23
Identities = 70/195 (35%), Positives = 107/195 (54%), Gaps = 4/195 (2%)
Frame = +2
Query: 167 SAMQSA---IKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNL-SR 334
+A+Q+A ++ V VIG G MG+GIA + AG NV L++ + AL + ++ + + SR
Sbjct: 283 AALQAAPRPVQTVAVIGAGTMGAGIAICALDAGLNVILLEQDDVALQRGQQRVAEHYQSR 342
Query: 335 VAKKMYKDNPQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDG 514
VA K S R++ TD + + ADLV+EA+ E++ VK +F+++D
Sbjct: 343 VAAGKVK------AAVAAASQARLSPTTDWVQLGR-ADLVIEAVFEDMPVKQDVFRKIDA 395
Query: 515 VAPSHTIFASNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKT 694
A S + A+NTS L ++ IA + R GLHFF+P VM+LL VV+G T+ T
Sbjct: 396 HARSGAVLATNTSYLDVDAIAQLTARPQDVLGLHFFSPANVMKLLEVVRGERTAADVVAT 455
Query: 695 MMEWGKSXGKTCITC 739
M GK K + C
Sbjct: 456 GMALGKKLKKLPVLC 470
>UniRef50_Q8W1L6 Cluster: Peroxisomal fatty acid beta-oxidation
multifunctional protein (MFP) [Includes: Enoyl-CoA
hydratase/3-2-trans-enoyl-CoA isomerase/3-
hydroxybutyryl-CoA epimerase (EC 4.2.1.17) (EC 5.3.3.8)
(EC 5.1.2.3); 3-hydroxyacyl-CoA dehydrogenase (EC
1.1.1.35)]; n=23; Magnoliophyta|Rep: Peroxisomal fatty
acid beta-oxidation multifunctional protein (MFP)
[Includes: Enoyl-CoA hydratase/3-2-trans-enoyl-CoA
isomerase/3- hydroxybutyryl-CoA epimerase (EC 4.2.1.17)
(EC 5.3.3.8) (EC 5.1.2.3); 3-hydroxyacyl-CoA
dehydrogenase (EC 1.1.1.35)] - Oryza sativa subsp.
japonica (Rice)
Length = 726
Score = 109 bits (263), Expect = 5e-23
Identities = 62/182 (34%), Positives = 99/182 (54%), Gaps = 2/182 (1%)
Frame = +2
Query: 185 IKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKK--MYKD 358
I+ V VIGGGLMGSGIA + +V L +V+ L + +K I NL + K+ + KD
Sbjct: 309 IRKVAVIGGGLMGSGIATALLVSNTSVVLKEVNPQFLQRGQKMIAANLEGLVKRGSLTKD 368
Query: 359 NPQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIF 538
+N ++ + A D ++ K D+V+EA++E I +K +F L+ V P H I
Sbjct: 369 K-------MNKAMSLLKGALDYSDF-KDVDMVIEAVIEKIPLKQSIFSDLEKVCPPHCIL 420
Query: 539 ASNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSX 718
A+NTS++ +N + +D+ G HFF+P +M LL +V+ +TS ++ GK
Sbjct: 421 ATNTSTIDLNVVGEKTNSQDRIIGAHFFSPAHIMPLLEIVRTEKTSPQAILDLITVGKMI 480
Query: 719 GK 724
K
Sbjct: 481 KK 482
>UniRef50_Q1Z537 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Photobacterium profundum 3TCK|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Photobacterium profundum 3TCK
Length = 713
Score = 109 bits (261), Expect = 9e-23
Identities = 67/187 (35%), Positives = 107/187 (57%), Gaps = 4/187 (2%)
Frame = +2
Query: 185 IKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALA----KAKKSIGTNLSRVAKKMY 352
+ V VIG G+MG GIA V+A G +V + D++ LA +A K + + R KK
Sbjct: 312 VTEVGVIGAGIMGGGIAYVTADKGADVVMKDINKAGLALGLTEANKLLAAQVERGRKKPL 371
Query: 353 KDNPQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHT 532
+ ++L RI + T + S DL++EA+VEN +K + +L+ V+P+ T
Sbjct: 372 A---------MGETLNRIQS-TLYNQPLTSNDLIIEAVVENPKIKEAVLAELEQVSPNAT 421
Query: 533 IFASNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGK 712
+ ASNTS+L I+ +A +K+ + F G+HFFNPV M L+ V++G +TS+ T +++
Sbjct: 422 L-ASNTSTLMISGLAQALKKPENFCGIHFFNPVHKMPLVEVIRGEQTSDQTITQAVKYVS 480
Query: 713 SXGKTCI 733
GKT I
Sbjct: 481 QLGKTPI 487
>UniRef50_Q1NHB4 Cluster: Fatty oxidation complex, alpha subunit;
n=2; Proteobacteria|Rep: Fatty oxidation complex, alpha
subunit - Sphingomonas sp. SKA58
Length = 722
Score = 109 bits (261), Expect = 9e-23
Identities = 69/184 (37%), Positives = 101/184 (54%), Gaps = 2/184 (1%)
Frame = +2
Query: 188 KNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKK--MYKDN 361
K V V+G G+MG+GIA VSA AG +V L+D K K L ++ +K + +D
Sbjct: 314 KKVGVLGAGMMGAGIAFVSANAGIDVVLIDRDTATAQKGKDYSAKVLGKLVEKGKLTQDK 373
Query: 362 PQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFA 541
V L RI T TD D+VVEA+ E+ +K + K+ + V P+ IFA
Sbjct: 374 ADAV-------LARI-TPTDDFALLDGCDMVVEAVFEDTAIKAETTKKAEAVLPAQAIFA 425
Query: 542 SNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXG 721
SNTS+L I+++A + D+F GLHFF+PV M L+ V+ G +TS+ T +++
Sbjct: 426 SNTSTLPISQLAQASRSPDQFIGLHFFSPVDRMGLVEVIMGKQTSKETLAKGLDFIAQLR 485
Query: 722 KTCI 733
KT I
Sbjct: 486 KTPI 489
>UniRef50_Q6D2L7 Cluster: Fatty acid oxidation complex subunit alpha
[Includes: Enoyl-CoA hydratase/3-hydroxybutyryl-CoA
epimerase (EC 4.2.1.17) (EC 5.1.2.3); 3-hydroxyacyl-CoA
dehydrogenase (EC 1.1.1.35)]; n=16;
Gammaproteobacteria|Rep: Fatty acid oxidation complex
subunit alpha [Includes: Enoyl-CoA
hydratase/3-hydroxybutyryl-CoA epimerase (EC 4.2.1.17)
(EC 5.1.2.3); 3-hydroxyacyl-CoA dehydrogenase (EC
1.1.1.35)] - Erwinia carotovora subsp. atroseptica
(Pectobacterium atrosepticum)
Length = 731
Score = 109 bits (261), Expect = 9e-23
Identities = 70/198 (35%), Positives = 110/198 (55%), Gaps = 2/198 (1%)
Frame = +2
Query: 146 VRNFSNSSAMQSAIKNVTVIGGGLMGSGIAQVSAQAGQ-NVTLVDVSNDALAKAKKSIGT 322
++ S +++ I V ++GGGLMG GIA V+A GQ V + D++ + A K
Sbjct: 309 LKKTSGAASEAKPIHRVGILGGGLMGGGIASVTATRGQLPVRIKDINEQGINHALKYNWQ 368
Query: 323 NLS-RVAKKMYKDNPQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLF 499
L+ RV K K P E ++ + I+ +TD + AD+V+EA+ E++ +K ++
Sbjct: 369 LLTKRVQSKRMK--PTERQRLMT----LISGSTDY-RGFEHADIVIEAVFEDLALKRQMI 421
Query: 500 KQLDGVAPSHTIFASNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSE 679
+++ A HTIFASNTSSL I++IA +R GLH+F+PV M L+ V+ + TS
Sbjct: 422 TEIEDHAAPHTIFASNTSSLPIHQIAEGARRPQLVVGLHYFSPVDKMPLVEVIPHAHTSA 481
Query: 680 ATYKTMMEWGKSXGKTCI 733
T T + + GKT I
Sbjct: 482 ETVATTVALARKQGKTAI 499
>UniRef50_Q2J6P6 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=10;
Actinomycetales|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Frankia sp. (strain CcI3)
Length = 624
Score = 108 bits (260), Expect = 1e-22
Identities = 65/182 (35%), Positives = 98/182 (53%)
Frame = +2
Query: 188 KNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNPQ 367
+ V V+G G MG+GIA+V A+AG V + DALA+++ + +L R + D+
Sbjct: 39 RRVGVVGLGTMGAGIAEVLAKAGLEVVGIARDADALARSRARVEHSLDRAGRHGKLDDAT 98
Query: 368 EVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFASN 547
L R+ T+ A A +LV+EAI E + K LF +LD + P T+F +N
Sbjct: 99 R-----EAVLARMRLGTELA-AVADCELVIEAIDERMSAKQALFARLDEICPPATVFLTN 152
Query: 548 TSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXGKT 727
TSSLS+ E+A+ R ++ G H+FNP PVMRL+ VV+ T ++ GKT
Sbjct: 153 TSSLSVTELAAGTARPERVLGTHWFNPAPVMRLVEVVRTVVTDPTVLAGVIGLVNDVGKT 212
Query: 728 CI 733
+
Sbjct: 213 AV 214
Score = 98.3 bits (234), Expect = 2e-19
Identities = 58/185 (31%), Positives = 97/185 (52%)
Frame = +2
Query: 185 IKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNP 364
+++V V+G G M GIA+V A++G +V L S LA I ++L A + +
Sbjct: 342 VRSVGVVGSGTMAGGIAEVLARSGHDVLLRARSERTLAATLAKIESSL---AASVARGRL 398
Query: 365 QEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFAS 544
+ ++ +L R+ TD E +L++EA+VE++ VK +LF LD +A + A+
Sbjct: 399 SDADRLA--ALARVRGTTDLGELGH-CELLLEAVVEDLAVKRELFADLDKIAAPGAVLAT 455
Query: 545 NTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXGK 724
TSSL + E A R G+H+FNP P M+L+ VV T + T++ ++ G+
Sbjct: 456 TTSSLPVIECAMATSRPRDVIGMHWFNPAPAMKLIEVVPTVLTGDDVTATVLALSRAAGR 515
Query: 725 TCITC 739
+ C
Sbjct: 516 HPVLC 520
>UniRef50_Q28N18 Cluster: 3-hydroxyacyl-CoA dehydrogenase
NAD-binding; n=23; Alphaproteobacteria|Rep:
3-hydroxyacyl-CoA dehydrogenase NAD-binding - Jannaschia
sp. (strain CCS1)
Length = 733
Score = 108 bits (259), Expect = 2e-22
Identities = 67/207 (32%), Positives = 108/207 (52%)
Frame = +2
Query: 113 IDSKMMQFKVIVRNFSNSSAMQSAIKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDA 292
I S + + + + + S +K V +IG G+MG+GIA VSA AG V L+D + D+
Sbjct: 303 IRSLFINKQALEKGANRPSVPDQTVKKVGIIGAGMMGAGIAYVSALAGIEVVLIDAAQDS 362
Query: 293 LAKAKKSIGTNLSRVAKKMYKDNPQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVE 472
A K+ L K K ++ K LG+I TD +A DL+VEA+ E
Sbjct: 363 -ADRGKAYSEGLLDKGMKRGKVTEEKKAKV----LGQITATTDY-DALNGCDLIVEAVFE 416
Query: 473 NIGVKHKLFKQLDGVAPSHTIFASNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLX 652
+ VK ++ + + + IFA+NTS+L I +A R ++F G+HFF+PV M L+
Sbjct: 417 DPKVKAEVTAKAEAAMNADGIFATNTSTLPITMLAKASSRAEQFIGIHFFSPVDKMALVE 476
Query: 653 VVKGSETSEATYKTMMEWGKSXGKTCI 733
++KG +T + +++ + KT I
Sbjct: 477 IIKGKQTGDVAVAKALDFVRQIRKTPI 503
>UniRef50_Q1GNH9 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=7;
cellular organisms|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Sphingopyxis alaskensis (Sphingomonas
alaskensis)
Length = 288
Score = 107 bits (258), Expect = 2e-22
Identities = 66/180 (36%), Positives = 93/180 (51%)
Frame = +2
Query: 194 VTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNPQEV 373
V VIG G MG+GIAQVSA AG +V L D+ K I L R+ + +
Sbjct: 3 VGVIGAGQMGAGIAQVSAGAGHDVLLADIDLARAEAGKAGIAKALGRLVAR-----EKMA 57
Query: 374 EKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFASNTS 553
+ + L RI D A + S DLV+EA E +K +F + + I ASNTS
Sbjct: 58 QSDADMLLARITPVADHAAFAPS-DLVIEAATEREEIKRAIFASVGEHLSATAILASNTS 116
Query: 554 SLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXGKTCI 733
S+ I +A +F G+HFFNPVPVM L+ +++G TS+ T T+ +G+ GK +
Sbjct: 117 SIPITRLAQAAPDPARFIGVHFFNPVPVMGLIELIRGLATSDDTLATVEAYGRGLGKQIV 176
>UniRef50_Q11ME9 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=36; Bacteria|Rep: 3-hydroxyacyl-CoA
dehydrogenase, NAD-binding - Mesorhizobium sp. (strain
BNC1)
Length = 740
Score = 107 bits (257), Expect = 3e-22
Identities = 65/183 (35%), Positives = 101/183 (55%)
Frame = +2
Query: 185 IKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNP 364
I+ V V+G G MG+GIA V+A+AG V L+D ++ K K + + KK +
Sbjct: 327 IRKVGVLGAGFMGAGIAYVTAKAGIPVVLIDRDQESADKGKAHSAGLMDGLIKKG-RATA 385
Query: 365 QEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFAS 544
+E EK ++ + TAT A + ADLV+EA+ E+ VK + ++ + S IFAS
Sbjct: 386 EEKEKLLS-----LITATPDYSALEGADLVIEAVFEDSAVKKEATEKAEAALKSSAIFAS 440
Query: 545 NTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXGK 724
NTS++ I +A KR F GLHFF+PV M L+ ++ G +T + M++ ++ K
Sbjct: 441 NTSTIPITSLAKNSKRPKNFIGLHFFSPVDRMMLVEIILGKKTGDKALALAMDYVRAIRK 500
Query: 725 TCI 733
T I
Sbjct: 501 TPI 503
>UniRef50_A4BGI3 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Reinekea sp. MED297|Rep: 3-hydroxyacyl-CoA dehydrogenase
- Reinekea sp. MED297
Length = 705
Score = 106 bits (254), Expect = 6e-22
Identities = 64/180 (35%), Positives = 99/180 (55%)
Frame = +2
Query: 194 VTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNPQEV 373
+ V+G G+MG+GIA A G V LVD ++A++ G + VAK+ +
Sbjct: 316 IGVVGAGMMGAGIAWACASKGLPVVLVDTEQ---SRAEQGKGYSERLVAKRFERGRLSAE 372
Query: 374 EKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFASNTS 553
E L RI T T++ DLV+EA+ E+ +K +++ + V TI ASNTS
Sbjct: 373 EGTA--LLNRI-TPTESMSELAECDLVIEAVFEDRALKADVYQLIQSVVSPETIIASNTS 429
Query: 554 SLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXGKTCI 733
+L I+ +A +V R D+F GLHFF+PV M LL +++G +TS++T + + KT I
Sbjct: 430 TLPISSLAGMVDRPDQFIGLHFFSPVDKMPLLEIIRGEQTSKSTVNAALAFSHQITKTPI 489
>UniRef50_A0QZR0 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Mycobacterium smegmatis str. MC2 155|Rep:
3-hydroxybutyryl-CoA dehydrogenase - Mycobacterium
smegmatis (strain ATCC 700084 / mc(2)155)
Length = 296
Score = 105 bits (253), Expect = 9e-22
Identities = 61/182 (33%), Positives = 97/182 (53%)
Frame = +2
Query: 188 KNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNPQ 367
K V V+G G MGSGIA V A+AG L D++ L + ++ + + D
Sbjct: 10 KTVAVLGAGTMGSGIATVMARAGHRTILYDINEANLERGIDTVHGFFDKSVRLGKLD--A 67
Query: 368 EVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFASN 547
+ DSL D A D+VVEA+ E++ +K + F +LD + P T+F +N
Sbjct: 68 TAGQAAKDSLSGSTELKDLAPC----DVVVEAVFEDLSLKKETFGRLDDIVPPTTLFHTN 123
Query: 548 TSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXGKT 727
TS+LS+ IAS + +++ G H+ NP P+M+L+ V G T++ +K +E+ S GKT
Sbjct: 124 TSTLSVTGIASGSRLRERVVGTHYCNPAPLMKLVEVANGRHTADWAHKATLEFLASLGKT 183
Query: 728 CI 733
+
Sbjct: 184 SV 185
>UniRef50_A0HAN1 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=2; Proteobacteria|Rep: 3-hydroxyacyl-CoA
dehydrogenase, NAD-binding - Comamonas testosteroni KF-1
Length = 706
Score = 105 bits (253), Expect = 9e-22
Identities = 65/180 (36%), Positives = 94/180 (52%)
Frame = +2
Query: 185 IKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNP 364
I V ++G G MG GIA A AG V L + AL + I N ++
Sbjct: 305 ICRVGILGAGTMGGGIAMAFANAGIPVVLCEREQAALDRGMAMIERNY-----QISVSRG 359
Query: 365 QEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFAS 544
+ V + + I D + A DLV+EA+ E++ +K +F QLD + TI A+
Sbjct: 360 GLTAEAVKERMQHIQQTLDLS-AFAEVDLVIEAVFEDMAIKRDVFVQLDRICRKGTILAT 418
Query: 545 NTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXGK 724
NTS L+INEIA+V +R + GLHFF+P VM+LL VV+G T +A + M+ + GK
Sbjct: 419 NTSRLNINEIAAVTQRPEDVIGLHFFSPANVMKLLEVVRGERTCDAVIASCMQMAVAIGK 478
>UniRef50_Q4REL3 Cluster: Chromosome 10 SCAF15123, whole genome
shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 10
SCAF15123, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 768
Score = 105 bits (252), Expect = 1e-21
Identities = 63/208 (30%), Positives = 104/208 (50%), Gaps = 22/208 (10%)
Frame = +2
Query: 176 QSAIKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMY- 352
Q +K + ++G GLMG+GIAQV+ G L D + LA+ ++ + A ++
Sbjct: 281 QREVKTLAILGAGLMGAGIAQVTVDKGVRTILKDTTAAGLARGQEQVYKGWVVTANPVFG 340
Query: 353 ---------------------KDNPQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIV 469
K + + F DS+ T + AD+V+EA+
Sbjct: 341 SSVVTHAGSYNSCLLLLRLNTKTKKKSITSFERDSILSNLTGQLDYSGFEKADMVIEAVF 400
Query: 470 ENIGVKHKLFKQLDGVAPSHTIFASNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLL 649
E+I +KH + K+++ V P H I A+NTS+L I +IA+ KR +K G+H+F+PV M+LL
Sbjct: 401 EDISIKHAVVKEVEAVVPPHCILATNTSALPIKDIAAASKRPEKVVGMHYFSPVDKMQLL 460
Query: 650 XVVKGSETSEATYKTMMEWGKSXGKTCI 733
++ +TS+ T + + G GK I
Sbjct: 461 EIITTEQTSKDTVASAVAVGLKQGKVII 488
>UniRef50_Q0SCS0 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=2;
Actinomycetales|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Rhodococcus sp. (strain RHA1)
Length = 284
Score = 105 bits (252), Expect = 1e-21
Identities = 62/183 (33%), Positives = 94/183 (51%)
Frame = +2
Query: 179 SAIKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKD 358
+A KNV V+GGG MG+GIAQV A G V + + + A + S G + + K+
Sbjct: 4 TAPKNVGVVGGGRMGAGIAQVFATLGSTVIIAESGDREAAVKRVSDGLDRAHERGKLGDV 63
Query: 359 NPQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIF 538
+P + LGR++T + DLVVEA+ E + +K + ++ T+
Sbjct: 64 DPATI-------LGRVSTVAAPDALPPALDLVVEAVPELVDLKLSVLSLVEKTVSPTTVI 116
Query: 539 ASNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSX 718
ASNTSS+SI E+ S + + G+HFFNPVP L+ +V+ T + + EW
Sbjct: 117 ASNTSSISIAELGSALGDPARLIGMHFFNPVPASSLVEIVRAPATDAGVVEKVREWVAQL 176
Query: 719 GKT 727
GKT
Sbjct: 177 GKT 179
>UniRef50_Q06BB6 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2;
Vibrio cholerae|Rep: 3-hydroxybutyryl-CoA dehydrogenase
- Vibrio cholerae
Length = 284
Score = 105 bits (252), Expect = 1e-21
Identities = 66/181 (36%), Positives = 105/181 (58%), Gaps = 4/181 (2%)
Frame = +2
Query: 194 VTVIGGGLMGSGIAQV----SAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDN 361
V V+G G+MG GI ++ + AG ++V +S D + + + LSR K K
Sbjct: 3 VAVVGNGVMGKGIVEILLCYTKLAGIE-SIVWISRDTESSIAST--SLLSRKVVKFLKTK 59
Query: 362 PQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFA 541
E++ ++S+ + +D + A KSA+LV+EA+ E+ VKH + ++ V TI A
Sbjct: 60 -SEIDFPPSESMAALQITSDFS-ALKSAELVIEAVSEDKDVKHDIMAKIAAVVDDTTIVA 117
Query: 542 SNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXG 721
SNTSSLSI E+A+ ++ + F GLHFFNP P+M L+ VV+G T E+ + + + +S G
Sbjct: 118 SNTSSLSITELAANFRKPENFLGLHFFNPAPMMSLVEVVRGLTTCESIIEKAVVFSRSIG 177
Query: 722 K 724
K
Sbjct: 178 K 178
>UniRef50_Q28UL9 Cluster: 3-hydroxyacyl-CoA dehydrogenase
NAD-binding; n=3; Alphaproteobacteria|Rep:
3-hydroxyacyl-CoA dehydrogenase NAD-binding - Jannaschia
sp. (strain CCS1)
Length = 687
Score = 104 bits (249), Expect = 3e-21
Identities = 59/170 (34%), Positives = 92/170 (54%)
Frame = +2
Query: 185 IKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNP 364
I + ++GGG MG+GIA G V L++ DA+A+A+ +I T + K+ D+
Sbjct: 282 ISKIAIVGGGTMGAGIAYACLSVGLPVVLLETDADAIARAQHNIDTLIGAGLKRGRLDDS 341
Query: 365 QEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFAS 544
+ D L T T+ A+ A LV+EA E++ VK +F +LD T+ A+
Sbjct: 342 GAAA--LRDRL----TLTEDYAAASDATLVIEAAFESMDVKKDIFAKLDAAVSPDTVLAT 395
Query: 545 NTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKT 694
NTS L ++ +A+ + + GLHFF P +MRLL +V G+ETS+ T
Sbjct: 396 NTSYLDVDVLAASTRDPSRILGLHFFAPAHIMRLLEIVTGAETSDRALAT 445
>UniRef50_A7HHZ4 Cluster: 3-hydroxyacyl-CoA dehydrogenase
NAD-binding; n=3; Bacteria|Rep: 3-hydroxyacyl-CoA
dehydrogenase NAD-binding - Anaeromyxobacter sp. Fw109-5
Length = 723
Score = 103 bits (248), Expect = 3e-21
Identities = 62/182 (34%), Positives = 100/182 (54%)
Frame = +2
Query: 188 KNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNPQ 367
+ V V+GGGLMGSGI+ V+A AG V + + + A KA S+ L K+ +
Sbjct: 329 RRVGVLGGGLMGSGISFVTANAGIPVRIRERDDAAAGKALGSVRALLDERVKR------R 382
Query: 368 EVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFASN 547
+++ D R+ TAT + D+++EA+ E++ +K ++ + + V P+ IFASN
Sbjct: 383 SIDRLERDERMRLVTATTDWSGYAAVDVLIEAVFEDLALKQEMVRAFEAVNPTG-IFASN 441
Query: 548 TSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXGKT 727
TSS+ I +IA + G+H+F+PV M LL ++ +TS+ T + GK GKT
Sbjct: 442 TSSIPITKIAEASAHPETVLGMHYFSPVQKMPLLEIIVTEKTSKEATATAVALGKKQGKT 501
Query: 728 CI 733
I
Sbjct: 502 VI 503
>UniRef50_A5N111 Cluster: Hbd2; n=5; Clostridiales|Rep: Hbd2 -
Clostridium kluyveri DSM 555
Length = 319
Score = 103 bits (248), Expect = 3e-21
Identities = 64/181 (35%), Positives = 96/181 (53%), Gaps = 1/181 (0%)
Frame = +2
Query: 185 IKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKK-MYKDN 361
IKNV V+G G MG+GI Q+ A++G NV + ++ +L + SI T+L + +K K N
Sbjct: 3 IKNVAVLGTGTMGNGIVQLCAESGLNVNMFGRTDASLERGFTSIKTSLKNLEEKGKIKTN 62
Query: 362 PQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFA 541
+ K + L RI EA + D V+E I E++ +K ++F +LD + I A
Sbjct: 63 ---ISKEI---LKRIKGVKTIEEAVEGVDFVIECIAEDLELKQEVFSKLDEICAPEVILA 116
Query: 542 SNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXG 721
SNTS LS +IA K ++ HF+NP + L+ VV G T T M+W + G
Sbjct: 117 SNTSGLSPTDIAINTKHPERVVIAHFWNPPQFIPLVEVVPGKHTDSKTVDITMDWIEHIG 176
Query: 722 K 724
K
Sbjct: 177 K 177
>UniRef50_A1FNB9 Cluster: 3-hydroxyacyl-CoA dehydrogenase precursor;
n=4; Proteobacteria|Rep: 3-hydroxyacyl-CoA dehydrogenase
precursor - Pseudomonas putida W619
Length = 313
Score = 103 bits (248), Expect = 3e-21
Identities = 67/183 (36%), Positives = 98/183 (53%), Gaps = 2/183 (1%)
Frame = +2
Query: 185 IKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNP 364
I VIG GLMG GIAQV AQAG V+L D L A + + NL ++ P
Sbjct: 4 ILQACVIGAGLMGHGIAQVFAQAGHKVSLYDPDAATLDLAPQRVAHNLDQMG---IASAP 60
Query: 365 QEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFAS 544
L I TD EA +AD+V+EA+ E + +K KLF + G AP HT+ AS
Sbjct: 61 ---------ILANIALFTDLREAVSNADIVIEAVPERLELKQKLFADIAGFAPPHTVLAS 111
Query: 545 NTSSLSINEIASVV--KRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSX 718
NTS + I EI ++ + + + G H++NP ++ L+ VV+ TS + +++ E +S
Sbjct: 112 NTSVIPITEIGEMLGSEARARLVGTHWWNPPHLVPLVEVVRTEHTSLSVFESTFELLQSL 171
Query: 719 GKT 727
GK+
Sbjct: 172 GKS 174
>UniRef50_Q5LKF7 Cluster: Fatty oxidation complex, alpha subunit;
n=5; Bacteria|Rep: Fatty oxidation complex, alpha
subunit - Silicibacter pomeroyi
Length = 714
Score = 103 bits (246), Expect = 6e-21
Identities = 60/185 (32%), Positives = 98/185 (52%)
Frame = +2
Query: 179 SAIKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKD 358
S ++ + ++G G+MG GIA +A AG V L D + +A + K T L K K
Sbjct: 315 SKVQRLGILGAGMMGQGIAFSAATAGLPVVLKDQTLEAAERGKAYTATLLD----KRVKQ 370
Query: 359 NPQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIF 538
E+ +++ + T TD A+ K DL++EA+ E I +K + + + + + I+
Sbjct: 371 GRMSAEE--REAVLALITPTDKADDLKGCDLIIEAVFEKIDIKDAVLAEHEALLAENGIW 428
Query: 539 ASNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSX 718
SNTS+L I +A+ R + F GLHFF+PV M LL ++ G +TS+ T ++ +
Sbjct: 429 GSNTSTLPITRLATGATRPENFVGLHFFSPVDKMPLLEIIAGEKTSDETLARAFDFARQI 488
Query: 719 GKTCI 733
KT I
Sbjct: 489 RKTPI 493
>UniRef50_A1SQH4 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=104; cellular organisms|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Nocardioides sp. (strain BAA-499 / JS614)
Length = 736
Score = 103 bits (246), Expect = 6e-21
Identities = 63/166 (37%), Positives = 97/166 (58%)
Frame = +2
Query: 182 AIKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDN 361
A+K V V+G G+MG+GIA A++G V L DV A+ A+K + + K + K
Sbjct: 324 AVK-VGVLGAGMMGAGIAYSCARSGMEVVLKDV---AVESAEKGKAYSEKLLDKAIAKGR 379
Query: 362 PQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFA 541
E +K + LGRI DAA+ + DLV+EA+ E+ +K ++F ++ +
Sbjct: 380 STEEKKA--ELLGRITATADAADLA-GCDLVIEAVFEDPSLKQQVFAEIAPYVDQDALLC 436
Query: 542 SNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSE 679
SNTS+L I E+AS V R F GLHFF+PV M L+ +++G++TS+
Sbjct: 437 SNTSTLPITELASGVDRPADFIGLHFFSPVDKMPLVEIIRGAKTSD 482
>UniRef50_A1IDF2 Cluster: 3-hydroxyacyl-CoA dehydrogenase/enoyl-CoA
hydratase/isomerase family protein precursor; n=1;
Candidatus Desulfococcus oleovorans Hxd3|Rep:
3-hydroxyacyl-CoA dehydrogenase/enoyl-CoA
hydratase/isomerase family protein precursor -
Candidatus Desulfococcus oleovorans Hxd3
Length = 801
Score = 103 bits (246), Expect = 6e-21
Identities = 65/191 (34%), Positives = 95/191 (49%), Gaps = 7/191 (3%)
Frame = +2
Query: 173 MQSAIKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMY 352
M IK VIG G+MG GIA + A AG L+D+ L +K +R+ K Y
Sbjct: 1 MSRKIKKAAVIGSGVMGGGIAALLASAGVETLLLDIVPFDLTDEQKKDPAARNRIVKFGY 60
Query: 353 K----DNPQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVA 520
P + + +L I D + D +VE +VEN+ +K +LFK+++ V
Sbjct: 61 DTIMMSRPAALMHSSDAALISIGNLEDDFDKLADCDWIVEVVVENLKIKQQLFKRIEPVR 120
Query: 521 PSHTIFASNTSSLSINEIASVVKR--KDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKT 694
+I +SNTS + + ++ + K F G HFFNPV M LL ++KG ETSE +
Sbjct: 121 KKGSIISSNTSGIPLKAMSEGLSSDFKQHFLGTHFFNPVRYMHLLEIIKGEETSEEVLRF 180
Query: 695 MMEWG-KSXGK 724
M +G K GK
Sbjct: 181 MAAFGEKRLGK 191
>UniRef50_A0ISW5 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=1; Serratia proteamaculans 568|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding - Serratia
proteamaculans 568
Length = 509
Score = 103 bits (246), Expect = 6e-21
Identities = 64/187 (34%), Positives = 100/187 (53%)
Frame = +2
Query: 179 SAIKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKD 358
SAI +V VIG G MG GIA + AQ G L + S + L +A+ I +L + K
Sbjct: 6 SAIHSVAVIGAGTMGRGIAYLLAQNGIRTLLYNRSGNNLNQARDYIIRDLDKKIDGG-KI 64
Query: 359 NPQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIF 538
+PQ+ + + + + + EA +DLV+E I E+ KH++ + I
Sbjct: 65 SPQKKGEILANLV-----FSPIFEAIADSDLVIETIAEHEATKHEILAAIAATVKKEAII 119
Query: 539 ASNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSX 718
A+NTSSLS+N++A+ V+ +F GLHFFNP P+M+L+ ++ TS AT + +
Sbjct: 120 ATNTSSLSLNKLAAGVENNARFIGLHFFNPAPLMKLIEIIPSYFTSRATSLRCQQLVTAI 179
Query: 719 GKTCITC 739
GK + C
Sbjct: 180 GKQFVVC 186
>UniRef50_Q9L6L5 Cluster: Fatty acid oxidation complex subunit alpha
[Includes: Enoyl-CoA
hydratase/Delta(3)-cis-Delta(2)-trans-enoyl-CoA
isomerase/3- hydroxybutyryl-CoA epimerase (EC 4.2.1.17)
(EC 5.3.3.8) (EC 5.1.2.3); 3-hydroxyacyl-CoA
dehydrogenase (EC 1.1.1.35)]; n=42; Proteobacteria|Rep:
Fatty acid oxidation complex subunit alpha [Includes:
Enoyl-CoA
hydratase/Delta(3)-cis-Delta(2)-trans-enoyl-CoA
isomerase/3- hydroxybutyryl-CoA epimerase (EC 4.2.1.17)
(EC 5.3.3.8) (EC 5.1.2.3); 3-hydroxyacyl-CoA
dehydrogenase (EC 1.1.1.35)] - Salmonella typhimurium
Length = 729
Score = 103 bits (246), Expect = 6e-21
Identities = 63/184 (34%), Positives = 101/184 (54%), Gaps = 2/184 (1%)
Frame = +2
Query: 188 KNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNPQ 367
K V+G G+MG GIA SA G V + D+ ND KS+ ++ AK + K +
Sbjct: 314 KQAAVLGAGIMGGGIAYQSAWKGVPVIMKDI-ND------KSLNLGMTEAAKLLNKQLER 366
Query: 368 -EVEKF-VNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFA 541
+++ + + I+ D A + D+VVEA+VEN VK + + + T+ A
Sbjct: 367 GKIDGLKLAGVISTIHPTLDYAGFDR-VDVVVEAVVENPKVKKAVLAETEQKVRPETVLA 425
Query: 542 SNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXG 721
SNTS++ I E+AS ++R + F G+HFFNPV M L+ +++G ++S+ T ++ W G
Sbjct: 426 SNTSTIPIGELASALERPENFCGMHFFNPVHRMPLVEIIRGEKSSDETIAKVVAWASKMG 485
Query: 722 KTCI 733
KT I
Sbjct: 486 KTPI 489
>UniRef50_A1BCA2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
precursor; n=1; Paracoccus denitrificans PD1222|Rep:
3-hydroxybutyryl-CoA dehydrogenase precursor -
Paracoccus denitrificans (strain Pd 1222)
Length = 371
Score = 102 bits (244), Expect = 1e-20
Identities = 66/183 (36%), Positives = 100/183 (54%), Gaps = 1/183 (0%)
Frame = +2
Query: 194 VTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKS-IGTNLSRVAKKMYKDNPQE 370
+ VIG G MG GIAQ A AG V ++ DA+ +A+++ +G + +A ++ +
Sbjct: 4 IAVIGLGTMGLGIAQTYAAAGFAV----LATDAVPEARETALGRLRAGLAPRVRAGKLAQ 59
Query: 371 VEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFASNT 550
+ ++ L RI T D +A + DL +EA+VE + VK LF L+ V + ASNT
Sbjct: 60 AD--LDAILARI-TVVDGPKAMGATDLAIEAVVERMPVKQSLFAALEAVVAPDAVLASNT 116
Query: 551 SSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXGKTC 730
SSLS+ +A + R ++ GLHFFNP PVM+L+ +V T A ++ GKT
Sbjct: 117 SSLSMAAMAEGLARPERLLGLHFFNPAPVMKLVELVAHPGTGAAALDRARRLTEAAGKTV 176
Query: 731 ITC 739
I C
Sbjct: 177 IPC 179
>UniRef50_A1FD08 Cluster: 3-hydroxybutyryl-CoA epimerase; n=13;
cellular organisms|Rep: 3-hydroxybutyryl-CoA epimerase -
Pseudomonas putida W619
Length = 423
Score = 101 bits (243), Expect = 1e-20
Identities = 64/183 (34%), Positives = 98/183 (53%)
Frame = +2
Query: 185 IKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNP 364
++ VIG G MG GI A+AG V +D ND A + + A+++ K
Sbjct: 18 VQQTAVIGAGTMGRGIVISLARAGLPVLWLD--NDPSA-TEAGLAMLAQTWAQQVGKGRI 74
Query: 365 QEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFAS 544
+ + + L R+ T E ++ ADLV+EA+ EN+ +K ++F+ LD I AS
Sbjct: 75 DQAQ--ADACLARVRQVTAYTELAE-ADLVIEAVYENLALKQEIFRALDSTLKPEAILAS 131
Query: 545 NTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXGK 724
NTS+L I+ IA+V R ++ GLHFF+P VM+LL VV+G T+ A + G+ GK
Sbjct: 132 NTSALDIDAIAAVTGRPEQVLGLHFFSPAHVMKLLEVVRGQLTAPAVLDAAVALGQRMGK 191
Query: 725 TCI 733
+
Sbjct: 192 EVV 194
>UniRef50_Q67L77 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Symbiobacterium thermophilum|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Symbiobacterium thermophilum
Length = 296
Score = 101 bits (242), Expect = 2e-20
Identities = 62/176 (35%), Positives = 92/176 (52%)
Frame = +2
Query: 200 VIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNPQEVEK 379
++G G G GIAQ+ A G V +V S + L +A++ + L +K ++
Sbjct: 8 IVGTGPSGRGIAQLVATQGLEVIMVGRSEEELEQARRQLDLALQHEIEKWALTQSEK--- 64
Query: 380 FVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFASNTSSL 559
L RI+ TD E +K AD V+ +V I ++F+ LD V I ASNTS+L
Sbjct: 65 --RAILARISMTTDINELAK-ADFVIATLVVEIAEDKEIFRTLDQVCRREVILASNTSTL 121
Query: 560 SINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXGKT 727
SI E+AS R DK G HF P+P R++ VV+G +TS+ T +M + G+T
Sbjct: 122 SITEMASATNRPDKVIGCHFLQPIPRTRVVQVVRGLKTSDETVSQVMALMERLGRT 177
>UniRef50_A4BL13 Cluster: Fatty oxidation complex, alpha subunit;
n=3; Proteobacteria|Rep: Fatty oxidation complex, alpha
subunit - Nitrococcus mobilis Nb-231
Length = 726
Score = 101 bits (242), Expect = 2e-20
Identities = 64/185 (34%), Positives = 101/185 (54%), Gaps = 1/185 (0%)
Frame = +2
Query: 182 AIKNVTVIGGGLMGSGIAQVSA-QAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKD 358
A++ V V+G GLMG+GI+ V+A +A V L DV LA K I R+ +++ +
Sbjct: 328 AVRRVGVLGAGLMGAGISFVTAARAKVPVRLKDVEPKGLASGLKYID---ERIDQRLSR- 383
Query: 359 NPQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIF 538
+ +F + T T +S DLV+EA+ E++ +KH++ ++++ + IF
Sbjct: 384 --HAISRFEAERARCRVTPTLDFSGCRSLDLVIEAVFEDLELKHRMIREVEANCNADVIF 441
Query: 539 ASNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSX 718
ASNTSSL + IA +R GLH+F+PV M LL V+ T+ T M +G++
Sbjct: 442 ASNTSSLPLARIAQAAERPQNVIGLHYFSPVDRMPLLEVIAHERTAPEVIATAMAFGRAQ 501
Query: 719 GKTCI 733
GKT I
Sbjct: 502 GKTPI 506
>UniRef50_Q8FRT3 Cluster: Putative 3-hydroxybutyryl-CoA
dehydrogenase; n=2; Corynebacterineae|Rep: Putative
3-hydroxybutyryl-CoA dehydrogenase - Corynebacterium
efficiens
Length = 294
Score = 101 bits (241), Expect = 2e-20
Identities = 67/180 (37%), Positives = 98/180 (54%)
Frame = +2
Query: 194 VTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNPQEV 373
V V+GGG MG+GIA AG +VT+VD+++ A+ A++ I ++ K+
Sbjct: 23 VGVLGGGRMGAGIAHSFLAAGAHVTVVDINDAAVEAARERITNDIEGSIKR-------GA 75
Query: 374 EKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFASNTS 553
E V L R+ +TD A A +VVEA+ E I +K F+++ AP + A+NTS
Sbjct: 76 EGTVEQWLDRLTLSTDTA-AFADHPVVVEAVPEIIDLKADSFRKIAAAAPG-AVIATNTS 133
Query: 554 SLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXGKTCI 733
SLS++++A V + GLH+FNPVP +L+ VV T EA EW GKT I
Sbjct: 134 SLSVSDLALSVD--NPVIGLHYFNPVPASKLVEVVVADSTPEALVDLAREWVAGLGKTPI 191
>UniRef50_Q6N3H7 Cluster: Enoyl-CoA hydratase; n=26; Bacteria|Rep:
Enoyl-CoA hydratase - Rhodopseudomonas palustris
Length = 699
Score = 101 bits (241), Expect = 2e-20
Identities = 61/182 (33%), Positives = 92/182 (50%), Gaps = 2/182 (1%)
Frame = +2
Query: 185 IKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKK--MYKD 358
+ V +IG G MG GIA A AG VTL++ + L + + N A + + D
Sbjct: 295 VSRVAIIGAGTMGGGIAMSFANAGIPVTLIETGEEQLKRGLGIMQKNWEATAARGGLPPD 354
Query: 359 NPQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIF 538
P + + +G N K ADL++EA+ E + VK ++F +D A +
Sbjct: 355 APAKRMALITGLVGLENV--------KDADLIIEAVFETMAVKKEVFTAVDAHAKPGAVL 406
Query: 539 ASNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSX 718
ASNTS LSI+EIA+ KR G+HFF+P VM+L +V+G++T+ T + K
Sbjct: 407 ASNTSYLSIDEIAATTKRPQDVLGMHFFSPANVMKLCEIVRGAKTAPDALLTAVSIAKKI 466
Query: 719 GK 724
K
Sbjct: 467 AK 468
>UniRef50_A0J682 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=1; Shewanella woodyi ATCC 51908|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Shewanella woodyi ATCC 51908
Length = 696
Score = 100 bits (240), Expect = 3e-20
Identities = 61/187 (32%), Positives = 98/187 (52%)
Frame = +2
Query: 149 RNFSNSSAMQSAIKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNL 328
+ + S++ I V V+G G MG GIA+ AG ++ ++ + +AL + ++
Sbjct: 293 QKLATSTSSTRTINTVGVVGAGNMGVGIARCFIDAGMDLIWIEQTEEALLRGMDNLRKGY 352
Query: 329 SRVAKKMYKDNPQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQL 508
K+ K + E + ++D + + +T + DLVVEA E++ VK +FK L
Sbjct: 353 Q---SKITKGHMTEQD--LDDKMQLVKGST-VYDRLAPCDLVVEAAFEDLEVKKIIFKAL 406
Query: 509 DGVAPSHTIFASNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATY 688
D I A+NTS L IN IA V R D+ GLHFF+P VM+L+ +V+ T++
Sbjct: 407 DQHCKDSAILATNTSYLDINSIAKVTSRPDQVVGLHFFSPAHVMKLIEIVRAENTADDVI 466
Query: 689 KTMMEWG 709
KTM+ G
Sbjct: 467 KTMLALG 473
>UniRef50_A4RUY4 Cluster: Predicted protein; n=5; cellular
organisms|Rep: Predicted protein - Ostreococcus
lucimarinus CCE9901
Length = 722
Score = 100 bits (239), Expect = 4e-20
Identities = 58/183 (31%), Positives = 100/183 (54%), Gaps = 2/183 (1%)
Frame = +2
Query: 185 IKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKK--MYKD 358
+K+V V+GGGLMGSGIA AG V L ++ + L I +NL+ + +K M +D
Sbjct: 304 MKSVGVVGGGLMGSGIATACLLAGIQVVLKEIKQEFLDAGVGRIQSNLTSMVRKGRMTED 363
Query: 359 NPQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIF 538
+++ V +L TD + + D+V+EA++EN+ +K K+F +L+ + I
Sbjct: 364 KARQLMSLVKPTL------TD--QDFRQCDMVIEAVIENLPLKQKIFCELERICKPDCIL 415
Query: 539 ASNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSX 718
++NTS++ I +IA+ +K ++ G HFF+P VM+L +++ T + K
Sbjct: 416 STNTSTIDITKIAAKMKNPERIVGAHFFSPAHVMQLFEIIRTDATPAQILVDTLGLSKQI 475
Query: 719 GKT 727
KT
Sbjct: 476 KKT 478
>UniRef50_A3QGY2 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=3; Proteobacteria|Rep: 3-hydroxyacyl-CoA
dehydrogenase, NAD-binding - Shewanella loihica (strain
BAA-1088 / PV-4)
Length = 708
Score = 99 bits (238), Expect = 6e-20
Identities = 58/173 (33%), Positives = 92/173 (53%)
Frame = +2
Query: 185 IKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNP 364
I+ V VIG G MG GIA G ++D++ +AL + I N KK
Sbjct: 299 IRKVAVIGSGTMGGGIAMNFINVGIPTQILDLNGEALERGLGVIRKNYEYTLKKGKLSQA 358
Query: 365 QEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFAS 544
Q +++ + ++ TD A+ + DLV+EA+ E + +K ++FK LD I A+
Sbjct: 359 Q-----LDERMALLSGTTDYADIA-DVDLVIEAVFEKMEIKKQVFKTLDATCKPGAILAT 412
Query: 545 NTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMME 703
NTS+L ++EIA+ R GLHFF+P VMRLL +V+ ++T+ T ++
Sbjct: 413 NTSTLDVDEIAAETSRPQDVLGLHFFSPANVMRLLEIVRANKTAPDALLTTVQ 465
>UniRef50_A0W3T3 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
precursor; n=1; Geobacter lovleyi SZ|Rep:
3-hydroxybutyryl-CoA dehydrogenase precursor - Geobacter
lovleyi SZ
Length = 285
Score = 99 bits (238), Expect = 6e-20
Identities = 66/188 (35%), Positives = 96/188 (51%), Gaps = 1/188 (0%)
Frame = +2
Query: 173 MQSAIKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKK-M 349
M I + V G G MG+GIAQ++A AG V L ALA A I T+L+++ +K +
Sbjct: 1 MNREIPLIGVAGAGSMGAGIAQLAAMAGFRVRLYARHASALADAAGRIETSLAKLHEKGL 60
Query: 350 YKDNPQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSH 529
+ P + RI+ + S DLV+EAI E + K +L +L V
Sbjct: 61 IGEEPTVIR-------ARISNCHEPVALS-DCDLVIEAIAEQMAAKCELLAELGAVLGKE 112
Query: 530 TIFASNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWG 709
I AS+TSSLSI + + +F G+HF NPVP+M L+ ++ GSETS T +
Sbjct: 113 AILASSTSSLSITALGAASGIPQRFIGMHFMNPVPLMELVELIAGSETSPRTIDIARQMV 172
Query: 710 KSXGKTCI 733
+ GK +
Sbjct: 173 TALGKQSV 180
>UniRef50_Q3A7N5 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Pelobacter carbinolicus DSM 2380|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Pelobacter carbinolicus (strain DSM 2380
/ Gra Bd 1)
Length = 304
Score = 99.5 bits (237), Expect = 7e-20
Identities = 63/177 (35%), Positives = 96/177 (54%)
Frame = +2
Query: 185 IKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNP 364
I V V+GGG MG IA A G VT+ D+S + L +K IG + + + P
Sbjct: 6 INQVLVVGGGTMGRQIAFQCAAHGYFVTIYDISAEVLQATQKRIGAYADYLVAEGHIQ-P 64
Query: 365 QEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFAS 544
Q ++ +N RI+ +TDA +A+ +ADL+ EA+ E+ +K ++F + D P TIF++
Sbjct: 65 QAAKRAIN----RISISTDARQAA-NADLLCEAVPEDPALKGEVFARFDRYCPQRTIFST 119
Query: 545 NTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKS 715
N S L ++IA R D+F LHF PV V L V+ + TS K + ++ KS
Sbjct: 120 NASLLVPSQIAKATGRPDRFLALHFHQPVWVGNLADVMPHAGTSSEVVKVVHDFAKS 176
>UniRef50_A6WDS7 Cluster: 3-hydroxyacyl-CoA dehydrogenase
NAD-binding; n=1; Kineococcus radiotolerans
SRS30216|Rep: 3-hydroxyacyl-CoA dehydrogenase
NAD-binding - Kineococcus radiotolerans SRS30216
Length = 681
Score = 99.5 bits (237), Expect = 7e-20
Identities = 61/184 (33%), Positives = 97/184 (52%), Gaps = 1/184 (0%)
Frame = +2
Query: 185 IKNVTVIGGGLMGSGIAQVSAQAGQ-NVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDN 361
+ +V V+G GLM S +A + Q V L DVS D + K + ++ + +K + +
Sbjct: 318 VTSVGVVGAGLMASQLALLLLHRLQVPVVLTDVSPDRVEKGVGFVREGVAELLRKG-RVS 376
Query: 362 PQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFA 541
P + G ++ + A AD VVEA+ E + VK + ++L+ + + A
Sbjct: 377 PDTANRLSASVSGSVDKS-----ALADADFVVEAVFEELAVKQDVLRELEPLLRPDAVIA 431
Query: 542 SNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXG 721
+NTSSLS+ +ASV++ +F G HFFNPV V+ L+ VV+ ET EA+ T G
Sbjct: 432 TNTSSLSVTAMASVLEHPQRFVGFHFFNPVAVLPLVEVVRTPETDEASLATAFAVGARLK 491
Query: 722 KTCI 733
KTC+
Sbjct: 492 KTCV 495
>UniRef50_Q3JZL6 Cluster: 3-hydroxyacyl-CoA dehydrogenase, putative;
n=7; Streptococcus agalactiae|Rep: 3-hydroxyacyl-CoA
dehydrogenase, putative - Streptococcus agalactiae
serotype Ia
Length = 377
Score = 99.1 bits (236), Expect = 1e-19
Identities = 72/225 (32%), Positives = 115/225 (51%), Gaps = 30/225 (13%)
Frame = +2
Query: 137 KVIVRNFSNSS--AMQSAIKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKK 310
K+ + FSN S IKN+TV G G++GS IA +A G +VT+ D++++AL K K+
Sbjct: 41 KLSSKTFSNISIGGCNMTIKNLTVAGSGVLGSQIAFQAAYKGMSVTIYDINDEALNKGKE 100
Query: 311 SIGTNLSRV-------AKKMYKDNPQEVEKFVN--------------DSL-------GRI 406
I L++V AK+ Y D + ++ N DSL +I
Sbjct: 101 RI-KKLAKVYQSEIETAKEAYSDKAKSIKYNKNLLPSLDHIFLSKVADSLDLIADLPNQI 159
Query: 407 NTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFASNTSSLSINEIASVV 586
+ + +A ADLV+EA+ E + +K +KQL VAPS TIFA+N+S+L ++ A +
Sbjct: 160 TFSKNLDQAVSDADLVIEAVPETVSIKEDFYKQLAKVAPSKTIFATNSSTLVPSQFADIT 219
Query: 587 KRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXG 721
R DKF +HF N + ++ ++ T + K + + K G
Sbjct: 220 GRPDKFLAMHFANNIWQNNIVEIMGHKGTDDEVIKEALTFSKDIG 264
>UniRef50_Q8ZAN0 Cluster: Fatty acid oxidation complex subunit alpha
[Includes: Enoyl-CoA
hydratase/Delta(3)-cis-Delta(2)-trans-enoyl-CoA
isomerase/3- hydroxybutyryl-CoA epimerase (EC 4.2.1.17)
(EC 5.3.3.8) (EC 5.1.2.3); 3-hydroxyacyl-CoA
dehydrogenase (EC 1.1.1.35)]; n=116; cellular
organisms|Rep: Fatty acid oxidation complex subunit
alpha [Includes: Enoyl-CoA
hydratase/Delta(3)-cis-Delta(2)-trans-enoyl-CoA
isomerase/3- hydroxybutyryl-CoA epimerase (EC 4.2.1.17)
(EC 5.3.3.8) (EC 5.1.2.3); 3-hydroxyacyl-CoA
dehydrogenase (EC 1.1.1.35)] - Yersinia pestis
Length = 729
Score = 99.1 bits (236), Expect = 1e-19
Identities = 60/186 (32%), Positives = 103/186 (55%), Gaps = 1/186 (0%)
Frame = +2
Query: 179 SAIKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTN-LSRVAKKMYK 355
+A K V+G G+MG GIA SA V + D++ ++L +G N +++ K +
Sbjct: 311 AAPKLAAVLGAGIMGGGIAYQSALKSVPVIMKDINENSL-----DLGMNEAAKLLNKQLE 365
Query: 356 DNPQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTI 535
+ K + L I D A + A ++VEA+VEN VK + +++ + T+
Sbjct: 366 RGKVDGLKMAS-ILATIRPTLDYAGIER-AQVIVEAVVENPKVKAAVLAEVEALIGEDTV 423
Query: 536 FASNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKS 715
ASNTS++ I+++A +KR + F G+HFFNPV M L+ +++G++TS+ T ++ +
Sbjct: 424 LASNTSTIPIDQLAKSLKRPENFCGMHFFNPVHRMPLVEIIRGAKTSDKTLAAVVAYATQ 483
Query: 716 XGKTCI 733
GKT I
Sbjct: 484 MGKTPI 489
>UniRef50_Q1DAC1 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenase;
n=1; Myxococcus xanthus DK 1622|Rep: Putative
3-hydroxyacyl-CoA dehydrogenase - Myxococcus xanthus
(strain DK 1622)
Length = 321
Score = 98.7 bits (235), Expect = 1e-19
Identities = 57/181 (31%), Positives = 101/181 (55%)
Frame = +2
Query: 185 IKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNP 364
+K + ++GGG MG GIA A AG+ V L + D+ +A+ L R A + +
Sbjct: 6 LKRIGMVGGGAMGCGIALELAIAGRQVVLYNTRADSSERAR----AKLERDASLLVETGL 61
Query: 365 QEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFAS 544
E+ ++GRI T AEA+ DLV+E+I E++ +K +LF++LD +A T+ A+
Sbjct: 62 LAPEQ-APAAIGRIRRTTVLAEAAVEQDLVIESIPEDLALKQQLFRELDQLAAPDTLLAT 120
Query: 545 NTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXGK 724
NT++LS+ IA R ++ H++ P ++ L+ ++ G +TS +T+ + + GK
Sbjct: 121 NTTALSVTAIARDCTRPERVLSAHYYLPAHLIPLVDIIPGEKTSPDAVETVRRFIEELGK 180
Query: 725 T 727
+
Sbjct: 181 S 181
>UniRef50_Q7WIS8 Cluster: Putative enoyl-CoA isomerase; n=2;
Bordetella|Rep: Putative enoyl-CoA isomerase -
Bordetella bronchiseptica (Alcaligenes bronchisepticus)
Length = 694
Score = 98.3 bits (234), Expect = 2e-19
Identities = 57/163 (34%), Positives = 90/163 (55%)
Frame = +2
Query: 185 IKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNP 364
I+ V V+G G MG+GI A AG V DV D LA+ + + + R+A + +
Sbjct: 287 IEQVAVVGAGTMGTGIVICLADAGLPVIWHDVDADRLAQGRAQVCQHFERLAARKRLTSR 346
Query: 365 QEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFAS 544
Q ++ + + T + A ++ ADL +EA+ E++ VK +F++LD V I +
Sbjct: 347 QAEQR-----VAAVATTGEMAGIAQ-ADLAIEAVFEDMAVKCAVFRELDRVLKPGAILGT 400
Query: 545 NTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSET 673
NTS+L ++ IA +R GLHFF+P PVM LL +V+G+ T
Sbjct: 401 NTSTLDVDRIAHSTRRPQDVVGLHFFSPAPVMPLLEIVRGAAT 443
>UniRef50_Q128W2 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=6; Proteobacteria|Rep: 3-hydroxyacyl-CoA
dehydrogenase, NAD-binding - Polaromonas sp. (strain
JS666 / ATCC BAA-500)
Length = 719
Score = 98.3 bits (234), Expect = 2e-19
Identities = 62/187 (33%), Positives = 98/187 (52%)
Frame = +2
Query: 164 SSAMQSAIKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAK 343
SS + V V+G G+MG+GIA A G L DVS D A+A K+ L++
Sbjct: 311 SSVPHATPLKVGVLGAGMMGAGIAYAQASRGLATVLKDVSLDK-AEAGKAYSARLTQPQV 369
Query: 344 KMYKDNPQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAP 523
+ P L RI TATD DL++EA+ E +K K+ ++ + +
Sbjct: 370 EKGHMTPANQAAL----LSRI-TATDQLADLAGCDLIIEAVFEQRDLKAKVTQEAEPLLA 424
Query: 524 SHTIFASNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMME 703
+ FASNTS+L I+ +A R +KF G+HFF+PV M+L+ +++G +T + T +
Sbjct: 425 AGGFFASNTSTLPISGLAVASSRPEKFIGIHFFSPVDKMKLVEIIRGRQTDDETVARAFD 484
Query: 704 WGKSXGK 724
+ ++ GK
Sbjct: 485 YVQALGK 491
>UniRef50_Q1LBV6 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=4; Proteobacteria|Rep: 3-hydroxyacyl-CoA
dehydrogenase, NAD-binding - Ralstonia metallidurans
(strain CH34 / ATCC 43123 / DSM 2839)
Length = 714
Score = 97.9 bits (233), Expect = 2e-19
Identities = 62/185 (33%), Positives = 97/185 (52%)
Frame = +2
Query: 179 SAIKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKD 358
+ K V ++G G+MG+GIA SA G L DVS D K K L + K K
Sbjct: 313 ATFKRVGILGAGMMGAGIAYASAMRGIEAVLKDVSLDHAGKGKLHSEKLLEKGVSKG-KI 371
Query: 359 NPQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIF 538
+P + ++ L RI DA+ + D+++EA+ E +K ++ ++ + + +F
Sbjct: 372 SPSKRDEV----LQRITPTADASGLA-GCDIIIEAVYEKRELKAEVTREAEPHLAENGLF 426
Query: 539 ASNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSX 718
ASNTS+L I +A + F GLHFF+PV M L+ ++KG +TS T +++ K
Sbjct: 427 ASNTSTLPITGLAEASASPENFIGLHFFSPVDRMPLVEIIKGKKTSSRTLAHAIDFVKQI 486
Query: 719 GKTCI 733
GKT I
Sbjct: 487 GKTPI 491
>UniRef50_A5IDB6 Cluster: 3-hydroxyacyl CoA dehydrogenase; n=9;
Gammaproteobacteria|Rep: 3-hydroxyacyl CoA dehydrogenase
- Legionella pneumophila (strain Corby)
Length = 284
Score = 97.9 bits (233), Expect = 2e-19
Identities = 60/164 (36%), Positives = 87/164 (53%)
Frame = +2
Query: 194 VTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNPQEV 373
+T++G G MGSGI Q+ AQ G VTL+D L KAK +I NL +A ++ +
Sbjct: 6 LTLLGAGTMGSGITQLFAQYGFYVTLIDNLQSQLDKAKDTIAKNLHYLALTQNLESTHSI 65
Query: 374 EKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFASNTS 553
E L I T T + K ++ ++E I EN K L++ L + I NTS
Sbjct: 66 ETI----LASI-TFTTKLDELKQSEYIIENITENWERKKALYQVLKKECSATCILGVNTS 120
Query: 554 SLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEAT 685
S+ I +IAS+V + G+HF NP P+M ++ V+KG T E T
Sbjct: 121 SIPITKIASLVDHPQRVIGVHFMNPAPMMPMVEVIKGYHTDELT 164
>UniRef50_Q0SJP3 Cluster: Bifunctional 3-hydroxyacyl-CoA
dehydrogenase/ 3-hydroxybutyryl-CoA epimerase; n=1;
Rhodococcus sp. RHA1|Rep: Bifunctional 3-hydroxyacyl-CoA
dehydrogenase/ 3-hydroxybutyryl-CoA epimerase -
Rhodococcus sp. (strain RHA1)
Length = 428
Score = 97.5 bits (232), Expect = 3e-19
Identities = 60/180 (33%), Positives = 97/180 (53%)
Frame = +2
Query: 194 VTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNPQEV 373
+ V+G G+MG+ IA A+AG +V L + + A+ KS A+K N
Sbjct: 31 IGVVGAGMMGAAIAYTCARAGADVVLWARTLEN-ARRGKSYSDRREAHARKAGTSNRPMS 89
Query: 374 EKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFASNTS 553
+ LGRI T T+ ++ L++EA+ EN+ VK ++ + ++ V + T+ AS TS
Sbjct: 90 QAL----LGRI-TPTECVRDLSTSALIIEAVAENVAVKQQVLQMVEAVTDAPTVLASTTS 144
Query: 554 SLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXGKTCI 733
+L I ++S ++R F G+HFF+PV M L+ V GS TS+AT + + + GK I
Sbjct: 145 TLPIATLSSKLQRPQYFIGMHFFSPVDRMSLVETVVGSRTSQATVAASLTYARRLGKVPI 204
>UniRef50_A1SEZ9 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Nocardioides sp. JS614|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Nocardioides sp. (strain BAA-499 /
JS614)
Length = 275
Score = 97.5 bits (232), Expect = 3e-19
Identities = 59/163 (36%), Positives = 94/163 (57%)
Frame = +2
Query: 191 NVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNPQE 370
++ V+GGG MG GIA + G VTLVDV+ D L +A+ + + +R +PQ
Sbjct: 4 SMVVVGGGTMGRGIAIAALATGFEVTLVDVAEDVLDRAQARVSEHFAR--------HPQP 55
Query: 371 VEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFASNT 550
G ++T T A + ++A++V+EA+ E + +K ++F+QL G AP T+ SNT
Sbjct: 56 -------DRGVLHTTTSLAGSLETAEVVIEAVPEILPLKTQIFQQLRG-APPGTLLVSNT 107
Query: 551 SSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSE 679
S++SI+ +A + G+HFFNP M L+ VV G+ TS+
Sbjct: 108 STMSISALAEACGGSSRVVGMHFFNPAHRMPLVEVVVGTRTSD 150
>UniRef50_A0K022 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
precursor; n=9; Actinomycetales|Rep:
3-hydroxybutyryl-CoA dehydrogenase precursor -
Arthrobacter sp. (strain FB24)
Length = 290
Score = 97.5 bits (232), Expect = 3e-19
Identities = 61/192 (31%), Positives = 97/192 (50%)
Frame = +2
Query: 158 SNSSAMQSAIKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRV 337
SNS V V+GGG MG+GIA G NV +V+ + A++ + + ++
Sbjct: 2 SNSVLPAGLPATVGVLGGGRMGAGIAHAFLINGANVLVVERDEASAEAARERVESAAAKS 61
Query: 338 AKKMYKDNPQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGV 517
++ D +++ + R++ D + K +LVVEA+ E+ +K ++++
Sbjct: 62 IERGATDGN------LDEMVSRLSVTVDYDDF-KDRELVVEAVPEDWELKVASLREIEAR 114
Query: 518 APSHTIFASNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTM 697
ASNTSSLS+N +A +KR F GLHFFNPVP L+ VV G +TS
Sbjct: 115 LSDDAYLASNTSSLSVNGLARELKRPGNFLGLHFFNPVPASTLIEVVLGEQTSPDLAAAA 174
Query: 698 MEWGKSXGKTCI 733
W ++ GKT +
Sbjct: 175 KRWVEALGKTAV 186
>UniRef50_Q4Q939 Cluster: Trifunctional enzyme alpha subunit,
mitochondrial-like protein; n=6; Trypanosomatidae|Rep:
Trifunctional enzyme alpha subunit, mitochondrial-like
protein - Leishmania major
Length = 726
Score = 97.1 bits (231), Expect = 4e-19
Identities = 58/182 (31%), Positives = 95/182 (52%), Gaps = 2/182 (1%)
Frame = +2
Query: 185 IKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNP 364
+ V VIG G+MGSGI A+ V + D++ +++ + ++ R ++
Sbjct: 307 VNRVGVIGAGVMGSGIVHYFAKNNIPVAVKDLTEESVKQGITNVRAEFERAVRRK----- 361
Query: 365 QEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQL--DGVAPSHTIF 538
+ V ++ + + T E + AD++VEA VE + +K K+ +QL DG+ S ++F
Sbjct: 362 RMVTAELDGKMALVTGGT-TNEVFRDADVIVEAAVEVMDIKKKVIQQLEKDGILHSKSLF 420
Query: 539 ASNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSX 718
A+NTSSLS+ E+ +V K G+HFFNPV M L+ V+KG TS +
Sbjct: 421 ATNTSSLSLTEMQTVAKCPHNIVGMHFFNPVSKMPLVEVIKGKSTSTEAAAAIFNLALKT 480
Query: 719 GK 724
GK
Sbjct: 481 GK 482
>UniRef50_Q3IIH0 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=4;
Bacteria|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Pseudoalteromonas haloplanktis (strain TAC 125)
Length = 281
Score = 96.7 bits (230), Expect = 5e-19
Identities = 61/179 (34%), Positives = 95/179 (53%), Gaps = 2/179 (1%)
Frame = +2
Query: 194 VTVIGGGLMGSGIAQVSAQAGQ--NVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNPQ 367
V++IG G M +GI QV + + V L+ + + +K + N+SR+A+K + Q
Sbjct: 3 VSIIGSGTMATGITQVLCLSNEVSKVNLIARTEEKALASKSTCAKNISRLARKGKISDEQ 62
Query: 368 EVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFASN 547
+ +L ++ + A ++DL++EAIVE+ K LF +L I ASN
Sbjct: 63 -----ASFALEKLYCNAELV-AVVNSDLIIEAIVEDFTAKMVLFSKLAEFINDSVIVASN 116
Query: 548 TSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXGK 724
TSSLSI ASV+ GLHFFNP P+M L+ ++ G ET+ A + + K+ GK
Sbjct: 117 TSSLSITAFASVLPNPQNVVGLHFFNPAPIMELVEIIVGHETAPAKIQLLQGLTKNLGK 175
>UniRef50_A0QZQ9 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Mycobacterium smegmatis str. MC2 155|Rep:
3-hydroxybutyryl-CoA dehydrogenase - Mycobacterium
smegmatis (strain ATCC 700084 / mc(2)155)
Length = 293
Score = 96.7 bits (230), Expect = 5e-19
Identities = 57/162 (35%), Positives = 87/162 (53%)
Frame = +2
Query: 194 VTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNPQEV 373
V V+G G MG+GI QV A +G++V +++ D + SI L + K E
Sbjct: 11 VGVLGLGTMGAGITQVFAASGRDVVVLEADQDRIDAGLASISAFLDT---GVAKGKLSET 67
Query: 374 EKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFASNTS 553
+K + L RI TD + + DLVVE++ EN VK L ++ V +T +NTS
Sbjct: 68 DK--SGLLARITATTDVTDLA-DVDLVVESVTENAEVKKDLLGRVAAVVGVNTPICTNTS 124
Query: 554 SLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSE 679
+LS+ E+A+ + + GLHFFNP P+ R + VV+ +T E
Sbjct: 125 ALSVTELAAALPNPSRVAGLHFFNPAPLQRTVEVVRALQTGE 166
>UniRef50_Q11BV6 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=1; Mesorhizobium sp. BNC1|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Mesorhizobium sp. (strain BNC1)
Length = 677
Score = 96.3 bits (229), Expect = 7e-19
Identities = 60/186 (32%), Positives = 98/186 (52%)
Frame = +2
Query: 176 QSAIKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYK 355
+ + + VIG G MG G+A AG++V L+D + AL +A ++ + L+R+
Sbjct: 282 EKRVTRLGVIGAGTMGVGLAVSLLAAGKSVVLIDKDDLALTRASAAVKSGLARL------ 335
Query: 356 DNPQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTI 535
+ ++++ + +L R+ A+ A ++ ++V+EA+VE+ VK + L +
Sbjct: 336 ERGGKLKEAPDAALARL-VASKELSAVENCEVVIEAVVESFEVKSAVLSDLHARLSPGAM 394
Query: 536 FASNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKS 715
SNTS L I E+A R D+F GLHFF PVPVM L+ VV ETS T + +
Sbjct: 395 VVSNTSYLDIAELARASGRPDRFLGLHFFAPVPVMTLVEVVPLPETSSHTLTVATQLVRD 454
Query: 716 XGKTCI 733
GK +
Sbjct: 455 MGKVAV 460
>UniRef50_Q5P5K3 Cluster: Alpha-subunit of fatty acid oxidation
complex; n=5; Betaproteobacteria|Rep: Alpha-subunit of
fatty acid oxidation complex - Azoarcus sp. (strain
EbN1) (Aromatoleum aromaticum (strain EbN1))
Length = 678
Score = 95.5 bits (227), Expect = 1e-18
Identities = 63/175 (36%), Positives = 94/175 (53%)
Frame = +2
Query: 158 SNSSAMQSAIKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRV 337
S+ ++ A + V V+G G+MG IA V A AG VTL D + + +A A +G
Sbjct: 307 SDDNSGDLAPRRVHVVGAGVMGGDIAAVCALAGMTVTLQDQAVERIAPA---VGRAAKLF 363
Query: 338 AKKMYKDNPQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGV 517
+K+ D + + V +L R+ ++ AD+V+EAI EN+ K LF QL+
Sbjct: 364 ERKLRGDTATKARQ-VRFALDRL-IPDPHGHGARRADVVIEAIFENLDAKRALFAQLERR 421
Query: 518 APSHTIFASNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEA 682
A + A+NTSSL I +I + + + G+HFFNPV M L+ VV G E S+A
Sbjct: 422 ARPDAVLATNTSSLRIEDIGAELANPARLVGIHFFNPVAQMPLVEVVAG-EASDA 475
>UniRef50_Q3KCL0 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=1; Pseudomonas fluorescens PfO-1|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Pseudomonas fluorescens (strain PfO-1)
Length = 703
Score = 95.5 bits (227), Expect = 1e-18
Identities = 60/180 (33%), Positives = 95/180 (52%)
Frame = +2
Query: 185 IKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNP 364
I V VIG G +G GIA A G V L+D+ L + K + N +++ K K +
Sbjct: 298 INKVAVIGAGTLGGGIAMSFADVGIPVALMDLDGRTLDRGLKRVRENY-QLSVKRGKLSA 356
Query: 365 QEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFAS 544
++++ + G + D A+ S ADL++EA+ E + KH++F L+ V I A+
Sbjct: 357 VQMQQRMELLFGTL----DYADLS-DADLIIEAVCEKMESKHQVFLALESVCKPGAILAT 411
Query: 545 NTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXGK 724
NTSSL I+ +A +V R G+HFF+P VMRL+ +V T+ +M+ + GK
Sbjct: 412 NTSSLDIDALAKMVSRPQDVIGMHFFSPANVMRLVEIVLCQTTAPDVVTAVMDIARRIGK 471
>UniRef50_A5D5N2 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Pelotomaculum thermopropionicum SI|Rep:
3-hydroxyacyl-CoA dehydrogenase - Pelotomaculum
thermopropionicum SI
Length = 319
Score = 95.5 bits (227), Expect = 1e-18
Identities = 57/164 (34%), Positives = 85/164 (51%)
Frame = +2
Query: 185 IKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNP 364
+K + +IG G MG IA + Q G +V L+DVS AL A++ I + L+ A K
Sbjct: 4 VKTLAIIGAGTMGHSIAAAALQHGVSVRLIDVSAPALETARRKIQSYLASAAGK----GG 59
Query: 365 QEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFAS 544
+ G + T + A AD+V+EA+ E + +K ++F QLD + P I A+
Sbjct: 60 GKGGAVPGHLAGVLETCMEMAAGVTGADMVIEAVPEKLDLKKEIFAQLDKLCPPSVILAT 119
Query: 545 NTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETS 676
NTS L I IAS R ++ G HF+ P ++ L+ VV TS
Sbjct: 120 NTSGLPITAIASAAARPERVLGTHFYMPAYLIPLVEVVCSDYTS 163
>UniRef50_A0JVH8 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=12; Actinomycetales|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Arthrobacter sp. (strain FB24)
Length = 723
Score = 95.5 bits (227), Expect = 1e-18
Identities = 57/184 (30%), Positives = 95/184 (51%), Gaps = 1/184 (0%)
Frame = +2
Query: 185 IKNVTVIGGGLMGSGIAQVSA-QAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDN 361
+ V V+G GLM S +A + A Q V + D+ A+ K +G + V K + K
Sbjct: 348 VTKVGVVGAGLMASQLALLFARQLKVPVVMTDIDQ---ARVDKGVGYVHAEVDKMLAK-- 402
Query: 362 PQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFA 541
+ + + + T + + +A AD V+EA+ E + VK ++F +++ + I A
Sbjct: 403 -KRISADAANRTKALVTGSVSKDAFADADFVIEAVFEELNVKKQVFAEVEAIVSPECILA 461
Query: 542 SNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXG 721
+NTSSLS+ +A+ + ++ G HFFNPV VM LL +V+ +T +A T E K
Sbjct: 462 TNTSSLSVTAMAADLAHPERLVGFHFFNPVAVMPLLEIVRAPKTDDAVLATAFELAKGLK 521
Query: 722 KTCI 733
KT +
Sbjct: 522 KTAV 525
>UniRef50_A3T2M8 Cluster: Enoyl-CoA
hydratase/isomerase/3-hydroxyacyl-CoA dehydrogenase;
n=4; cellular organisms|Rep: Enoyl-CoA
hydratase/isomerase/3-hydroxyacyl-CoA dehydrogenase -
Sulfitobacter sp. NAS-14.1
Length = 695
Score = 95.1 bits (226), Expect = 2e-18
Identities = 57/175 (32%), Positives = 90/175 (51%)
Frame = +2
Query: 200 VIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNPQEVEK 379
V+GGG MG+ IA A AG +VT+V+ S + A K++ + + + + K
Sbjct: 291 VVGGGNMGAAIAYTLATAGISVTVVERSASSAEWASKNLQKLIDQGISRGILS--VDAAK 348
Query: 380 FVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFASNTSSL 559
V D L ++ +A DL +EA E+ VK + +L+G P TI A+NTS L
Sbjct: 349 TVEDRLVTVS----GYDALPPTDLAIEAAFEDFAVKTAILTELEGALPPETIIATNTSYL 404
Query: 560 SINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXGK 724
+N ++ +K +F G+HFF+P +M+LL VV+ TS+ T + GK
Sbjct: 405 DVNRLSDGLKHPARFVGMHFFSPAHIMKLLEVVRSDRTSDGTLGAALVLAHRLGK 459
>UniRef50_Q24N80 Cluster: Putative uncharacterized protein; n=1;
Desulfitobacterium hafniense Y51|Rep: Putative
uncharacterized protein - Desulfitobacterium hafniense
(strain Y51)
Length = 313
Score = 94.7 bits (225), Expect = 2e-18
Identities = 63/175 (36%), Positives = 95/175 (54%)
Frame = +2
Query: 200 VIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNPQEVEK 379
V+G G+MGSGIAQ+ A G V L D + L +AK+ I N+ + K+ +E E+
Sbjct: 9 VVGAGVMGSGIAQLYACKGFQVALYDKFPEQLDRAKQLIANNMENLIKEGLATQ-EEAER 67
Query: 380 FVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFASNTSSL 559
+ I+ T+ + + ADLV+E++ EN VK + F QLD + S I SNTS+
Sbjct: 68 ----TKTLISYETELEKCAPQADLVLESVFENADVKRETFAQLDKLCASDCILCSNTSAS 123
Query: 560 SINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXGK 724
+I EIA V ++ H+FNP +M L+ VV G +TS+ T + + GK
Sbjct: 124 NIFEIAP-VSHPERQIITHYFNPPFIMDLVEVVMGPKTSDETLDKVKSFLIQVGK 177
>UniRef50_UPI00006A277A Cluster: UPI00006A277A related cluster; n=1;
Xenopus tropicalis|Rep: UPI00006A277A UniRef100 entry -
Xenopus tropicalis
Length = 666
Score = 94.3 bits (224), Expect = 3e-18
Identities = 60/180 (33%), Positives = 90/180 (50%)
Frame = +2
Query: 185 IKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNP 364
I+ V ++G G MG GIA A G +V+V+++ L + + N A K
Sbjct: 290 IRKVGIVGAGTMGGGIAMNFANVGIPTVVVEVNDETLQRGLGLVRRNYEASAAKGRLTAE 349
Query: 365 QEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFAS 544
Q V + + A D A A DLV+EA+ EN+ +K + +L VA I A+
Sbjct: 350 Q-----VAGRMALLQGALDYA-ALAECDLVIEAVFENMALKQDICAKLGAVAKPGAIIAT 403
Query: 545 NTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXGK 724
NTS+L ++ +A R G+HFF+P VMRLL VV+G+ T+ T+M+ GK
Sbjct: 404 NTSTLDVDVLARATGRSADVVGMHFFSPAHVMRLLEVVRGAATAPDVLATIMKLAARIGK 463
>UniRef50_Q73Q34 Cluster: 3-hydroxyacyl-CoA dehydrogenase, putative;
n=1; Treponema denticola|Rep: 3-hydroxyacyl-CoA
dehydrogenase, putative - Treponema denticola
Length = 309
Score = 93.9 bits (223), Expect = 4e-18
Identities = 60/178 (33%), Positives = 104/178 (58%), Gaps = 1/178 (0%)
Frame = +2
Query: 194 VTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSR-VAKKMYKDNPQE 370
V V+G G MG GI++V A+AG V ++ +++ +L A I +L+ VA+ + + +
Sbjct: 10 VAVVGDGTMGHGISEVFAKAGHTVQIIGLNDASLKSALDRIKLSLNEFVAEGLV--SASD 67
Query: 371 VEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFASNT 550
++ V GRI+ +TD +A +A +V+EA+ EN+ +K + F +L+ + P TI A+
Sbjct: 68 IDTIV----GRISFSTDIQKAEDAA-IVIEALPENMDLKTETFGKLEKICPQDTILAT-A 121
Query: 551 SSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXGK 724
S S++E+ + VK++D+ HF+ P ++ L+ V ETS+AT T E K GK
Sbjct: 122 SGHSVSEVIAQVKKRDRVIATHFWFPPQLLPLVEVCGAPETSKATIDTTCELLKGIGK 179
>UniRef50_Q1YTH7 Cluster: Fatty oxidation complex, alpha subunit;
n=4; Gammaproteobacteria|Rep: Fatty oxidation complex,
alpha subunit - gamma proteobacterium HTCC2207
Length = 718
Score = 93.9 bits (223), Expect = 4e-18
Identities = 54/180 (30%), Positives = 94/180 (52%)
Frame = +2
Query: 185 IKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNP 364
IK VIG G+MG GIA +A G +V + D++ AL + L++ K+
Sbjct: 317 IKTAGVIGAGIMGGGIAYQNAIRGYSVVMKDINQPALDLGIQEANKLLAKGVKR-----G 371
Query: 365 QEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFAS 544
+ E+ L I + + ++ + +++VEA+VE VK + ++ + + + S
Sbjct: 372 KLTEEKAGQILSLIKPSLEDSDVAP-CNMLVEAVVELESVKKMVLPAVEALLDNSAVITS 430
Query: 545 NTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXGK 724
NTS++SIN +A ++R F G+HFFNPV M L+ +++G TS+ T + + GK
Sbjct: 431 NTSTISINRLAESLERPQNFCGMHFFNPVHAMPLVEIIRGENTSDETIAAVCAYALGLGK 490
>UniRef50_Q2SGR6 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Hahella chejuensis KCTC 2396|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Hahella chejuensis (strain KCTC 2396)
Length = 712
Score = 93.1 bits (221), Expect = 6e-18
Identities = 60/175 (34%), Positives = 96/175 (54%)
Frame = +2
Query: 176 QSAIKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYK 355
+ I++V +IG G MG GIA A G VTL D + ++LA+A K A +++
Sbjct: 318 RDTIQHVHIIGAGAMGGGIAAWCALKGLRVTLQDQNPESLAEAYKH--------ANGLFR 369
Query: 356 DNPQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTI 535
D + ++ + R+ + + ADLV+EAI E + K +L+++++ S
Sbjct: 370 DKLGD-KRLAMVARDRLTPDPEGVGLAW-ADLVLEAIPEKLEAKRQLYQEIEPRMKSDAT 427
Query: 536 FASNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMM 700
ASNTSS+ I+E+A + ++ GLHFFNPV M L+ V+KG +TS+ T M
Sbjct: 428 LASNTSSIPIDELARGLAHPERLVGLHFFNPVEKMLLVEVIKGDKTSQQTLDRAM 482
>UniRef50_Q89SH2 Cluster: Blr2428 protein; n=7; Rhizobiales|Rep:
Blr2428 protein - Bradyrhizobium japonicum
Length = 715
Score = 92.7 bits (220), Expect = 9e-18
Identities = 57/160 (35%), Positives = 89/160 (55%)
Frame = +2
Query: 179 SAIKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKD 358
+A+K+V VIG G MG IA A G V+L D+ + +A A K ++ +K
Sbjct: 338 NAVKHVHVIGAGAMGGDIAAWCAGQGLRVSLADMKAEPIAGAVKRAAELYGKIIRK---- 393
Query: 359 NPQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIF 538
P EV D+L R+ D E ++ADLV+EA+ E + +K K++ L+ I
Sbjct: 394 -PTEVR----DALDRLIPDMDG-EGVRNADLVIEAVPEKLELKQKVYAGLEPKMKPGAIL 447
Query: 539 ASNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVV 658
A+NTSS+ + ++ + + R D+ GLHFFNPV ++L+ VV
Sbjct: 448 ATNTSSIPLQDLRTTLARPDRLVGLHFFNPVSRLQLVEVV 487
>UniRef50_A3M4C7 Cluster: PaaC; n=1; Acinetobacter baumannii ATCC
17978|Rep: PaaC - Acinetobacter baumannii (strain ATCC
17978 / NCDC KC 755)
Length = 435
Score = 92.7 bits (220), Expect = 9e-18
Identities = 46/99 (46%), Positives = 65/99 (65%), Gaps = 4/99 (4%)
Frame = +2
Query: 428 EASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFASNTSSLSINEIASVVKRKDKFG 607
EA + ADLV+EA+VE VK LFKQL + + TIFASNTSS+S+ I++ + ++
Sbjct: 6 EALRDADLVIEAVVEKKEVKQSLFKQLAEICSAQTIFASNTSSISVTAISAGIAHPERVV 65
Query: 608 GLHFFNPVPVMRLLXVVKGSETSE----ATYKTMMEWGK 712
GLHFFNP PVM+L+ +V+G +T A M++W K
Sbjct: 66 GLHFFNPAPVMKLVEIVQGLKTPNSLCLALKNLMLDWKK 104
>UniRef50_A1WHE6 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Verminephrobacter eiseniae EF01-2|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Verminephrobacter eiseniae (strain
EF01-2)
Length = 319
Score = 92.3 bits (219), Expect = 1e-17
Identities = 55/181 (30%), Positives = 97/181 (53%)
Frame = +2
Query: 179 SAIKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKD 358
S + ++TV+G G++G I+ SA G++V + D+S +ALA+ + + + A D
Sbjct: 2 SYVNHLTVLGAGVLGGQISWHSAFKGKSVVVYDISEEALARCRAA----QAHYAAIYQTD 57
Query: 359 NPQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIF 538
E V + R+ ATD A A SADLV+EA+ E VK +++Q+ + P+HT+
Sbjct: 58 AVGASEADVAGARQRLTFATDLASAVASADLVIEAVPEIPQVKTSVYQQMAPLLPAHTLI 117
Query: 539 ASNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSX 718
A+N+S+ ++ A+ R DKF LH+ N + L+ ++ + T+ T + +
Sbjct: 118 ATNSSTFLPSDFAAATGRPDKFCALHYANYIWAANLVEIMPHAATARTTLDDVTRFAIET 177
Query: 719 G 721
G
Sbjct: 178 G 178
>UniRef50_A1I839 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Candidatus Desulfococcus oleovorans Hxd3|Rep:
3-hydroxybutyryl-CoA dehydrogenase - Candidatus
Desulfococcus oleovorans Hxd3
Length = 289
Score = 92.3 bits (219), Expect = 1e-17
Identities = 61/183 (33%), Positives = 90/183 (49%)
Frame = +2
Query: 185 IKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNP 364
IK V + G G MG I A G V L DV DAL A++++ + ++ P
Sbjct: 6 IKRVLIAGAGTMGRSIGLSCAVRGCEVILYDVKEDALEAARRAMAVKIDKMVPAGAL-TP 64
Query: 365 QEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFAS 544
+ E I T TD A A ADLV E++ E+ +K + F++L GV P TIF +
Sbjct: 65 EAAESIK----ANITTTTDLAAAGADADLVSESVPEDPDIKGEFFEKLHGVCPERTIFTT 120
Query: 545 NTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXGK 724
NTSSL + A+ R D+F HF P +L+ V+ + TS T +T+ + + G
Sbjct: 121 NTSSLVPSMFAARTGRPDRFLAFHFH---PGFKLVDVMGHAGTSAETVETVRRFAERIGH 177
Query: 725 TCI 733
+ I
Sbjct: 178 SPI 180
>UniRef50_A0JTB4 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=5;
Actinomycetales|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Arthrobacter sp. (strain FB24)
Length = 333
Score = 91.9 bits (218), Expect = 1e-17
Identities = 61/188 (32%), Positives = 94/188 (50%), Gaps = 1/188 (0%)
Frame = +2
Query: 164 SSAMQSAIKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSND-ALAKAKKSIGTNLSRVA 340
SSA SA K + V+G G MG GIAQV A G V L DVS + A + + + + VA
Sbjct: 13 SSAANSARK-IAVVGSGYMGGGIAQVLALGGARVALADVSAEVAQSNYDRLLAESDQFVA 71
Query: 341 KKMYKDNPQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVA 520
++ E+ K + A D EA AD + EA+ E I +KH+ ++ A
Sbjct: 72 DGLFPAGSTEILK------QNLWAARDIEEAVADADFIEEAVPEIIAIKHQTLARISAAA 125
Query: 521 PSHTIFASNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMM 700
I SNTS++SI +++ V ++F G+HF NP P + + ++ + TS T +
Sbjct: 126 RPDAIIGSNTSTISIADLSEPVTNPERFLGVHFSNPSPFIPGVEIIPHAGTSATTVGAVR 185
Query: 701 EWGKSXGK 724
+ + GK
Sbjct: 186 DLVHAAGK 193
>UniRef50_Q5LVG3 Cluster: Enoyl-CoA
hydratase/isomerase/3-hydroxyacyl-CoA dehydrogenase;
n=2; Rhodobacteraceae|Rep: Enoyl-CoA
hydratase/isomerase/3-hydroxyacyl-CoA dehydrogenase -
Silicibacter pomeroyi
Length = 681
Score = 91.1 bits (216), Expect = 3e-17
Identities = 61/199 (30%), Positives = 97/199 (48%)
Frame = +2
Query: 137 KVIVRNFSNSSAMQSAIKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSI 316
+++ R + + + V ++GGGLMG+G+A G +VT+++ + A A+A +
Sbjct: 270 RLVARPDAIAGVTPRELTRVAIVGGGLMGAGVAMACLGGGLSVTVIE-RDAAAAQAAQER 328
Query: 317 GTNLSRVAKKMYKDNPQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKL 496
L K K +P D L R+ T A+AS ADL +EA+ E++ VK +
Sbjct: 329 VAGLVAAGVKRGKISPDAQA----DMLARLATTDTYADAS-DADLAIEAVFEDLDVKRIV 383
Query: 497 FKQLDGVAPSHTIFASNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETS 676
F L V I A+NTS L + + + + GLHFF+P VM+LL +VK +T+
Sbjct: 384 FADLAAVMRPDAILATNTSYLDPQLVFAGIANPARCLGLHFFSPAHVMKLLEIVKTPDTA 443
Query: 677 EATYKTMMEWGKSXGKTCI 733
T GK K +
Sbjct: 444 PEVLATGFALGKRLRKISV 462
>UniRef50_Q1IMY8 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
precursor; n=1; Acidobacteria bacterium Ellin345|Rep:
3-hydroxybutyryl-CoA dehydrogenase precursor -
Acidobacteria bacterium (strain Ellin345)
Length = 278
Score = 90.6 bits (215), Expect = 3e-17
Identities = 56/169 (33%), Positives = 89/169 (52%)
Frame = +2
Query: 179 SAIKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKD 358
S ++ + VIG G MG IAQ +A G L D+ +AL KA+ +I L R +
Sbjct: 2 SEVRIIAVIGAGTMGRSIAQAAAVGGFRTILEDILPNALRKAEDAIRAELGRAVSTGSVE 61
Query: 359 NPQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIF 538
++ + +L RI A++ +A++ AD+V+EA+ + + K ++F LD V T+
Sbjct: 62 -----QREADAALARIEYASNLEDAARDADMVIEAVPDELESKLEIFVLLDKVCRPETMI 116
Query: 539 ASNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEAT 685
S+T SI E+ASV+ R K + F P L +V+G ETS+ T
Sbjct: 117 VSHTQIQSITELASVIYRAPKCIAMWFPKPPQTSVALEIVRGLETSDET 165
>UniRef50_Q0SEM1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Rhodococcus sp. RHA1|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Rhodococcus sp. (strain RHA1)
Length = 286
Score = 90.6 bits (215), Expect = 3e-17
Identities = 56/184 (30%), Positives = 92/184 (50%)
Frame = +2
Query: 182 AIKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDN 361
++ +V V+G G MG+G+A+ AQAG +V +VD A+ +A+ + +L
Sbjct: 5 SVMSVGVVGAGTMGAGVAECLAQAGHDVIVVDPDPQAVDQARSRMRDSLRLAILLGRAGG 64
Query: 362 PQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFA 541
P+ E V + TD +A+ +V+E + E I +K K+F +LD V + A
Sbjct: 65 PKPAE--VTARVHWTGEMTDLRDAA----VVIECVPERIDLKEKVFAELDRVCAPDALLA 118
Query: 542 SNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXG 721
S TS + ++ +A R ++ GLHF NP P+ + VV+G TS + + S
Sbjct: 119 SCTSGIPVDRLADTTTRPERVVGLHFMNPAPLKDTVEVVRGPRTSPQSLDRALALLASLN 178
Query: 722 KTCI 733
KT I
Sbjct: 179 KTGI 182
>UniRef50_A7INS1 Cluster: 3-hydroxyacyl-CoA dehydrogenase
NAD-binding; n=5; Alphaproteobacteria|Rep:
3-hydroxyacyl-CoA dehydrogenase NAD-binding -
Xanthobacter sp. (strain Py2)
Length = 789
Score = 90.2 bits (214), Expect = 5e-17
Identities = 60/189 (31%), Positives = 95/189 (50%), Gaps = 4/189 (2%)
Frame = +2
Query: 185 IKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNP 364
IK V VIG G+MG+GIA A AG V L+D+ + A + +I + +K+ K +P
Sbjct: 18 IKKVAVIGAGVMGAGIAAHVANAGIEVLLLDIVPEGAAN-RNAIA---EKAVEKLLKADP 73
Query: 365 QEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFAS 544
L D S D +VEA++E + +K L+ +++ + +S
Sbjct: 74 AAFMSKRAAKLVTAGNIEDNLSDLASCDWIVEAVIERLDIKQALYAKIEAARRPGSAVSS 133
Query: 545 NTSSLSINEIASVVK---RKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGK- 712
NTS++ + ++ + + R+D F HFFNP MRLL +V G ET+ AT + +
Sbjct: 134 NTSTIPLGDLTAGLPESFRRD-FLITHFFNPPRYMRLLEIVAGPETNPATVAAVARFADV 192
Query: 713 SXGKTCITC 739
GKT +TC
Sbjct: 193 KLGKTVVTC 201
>UniRef50_A4WWF6 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=5; Rhodobacteraceae|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Rhodobacter sphaeroides ATCC 17025
Length = 673
Score = 90.2 bits (214), Expect = 5e-17
Identities = 61/196 (31%), Positives = 88/196 (44%)
Frame = +2
Query: 137 KVIVRNFSNSSAMQSAIKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSI 316
+ VR + S + + + VIGGG MGSGIA A AG TL + DAL K +
Sbjct: 274 RAAVRPAALRSIEPAPMARIGVIGGGTMGSGIAAAIAAAGLEATLAETGPDALEAGIKRV 333
Query: 317 GTNLSRVAKKMYKDNPQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKL 496
+ D D L R++ + DLV+EA+ E++ VK ++
Sbjct: 334 RAIFEAQVTRGLTDRAGAA-----DRLARVSGTVGLGPLA-DCDLVIEAVFEDLAVKRRV 387
Query: 497 FKQLDGVAPSHTIFASNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETS 676
F+ L + I A+NTS L I + + D+F LHFF+P VM+LL +V T+
Sbjct: 388 FEDLTRLCRPDAILATNTSYLDPERIVAGLPNPDRFIALHFFSPAQVMKLLEIVPLVATT 447
Query: 677 EATYKTMMEWGKSXGK 724
T T GK
Sbjct: 448 SRTLATGFALAARLGK 463
>UniRef50_A3JQP6 Cluster: Acetoacetyl-CoA reductase; n=2;
Alphaproteobacteria|Rep: Acetoacetyl-CoA reductase -
Rhodobacterales bacterium HTCC2150
Length = 780
Score = 90.2 bits (214), Expect = 5e-17
Identities = 57/190 (30%), Positives = 93/190 (48%), Gaps = 3/190 (1%)
Frame = +2
Query: 179 SAIKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKD 358
S K + VIG G MGSGIA A AG V L+D+ K S ++ K
Sbjct: 4 SDFKRIAVIGAGTMGSGIAGQIANAGHEVLLLDLPG------KNSRNEVTENAVTRLLKS 57
Query: 359 NPQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIF 538
+P + +L ++ D + D +VEAIVE + +K L+++L+ V +
Sbjct: 58 DPPALMHKKRAALIKVGNIEDDFDKLAECDWIVEAIVERLDIKKALYQRLNDVISPECVV 117
Query: 539 ASNTSSLSINEIASVVKR--KDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWG- 709
SNTS++ I + + + + +F H+FNPV MRLL +V+G++T+ A + +
Sbjct: 118 TSNTSTIPIKLLVEDMPQDFRARFAITHYFNPVRYMRLLELVRGADTNPAVMDRLARYND 177
Query: 710 KSXGKTCITC 739
+ GK + C
Sbjct: 178 EILGKGVVQC 187
>UniRef50_Q0SEV8 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=34;
Bacteria|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Rhodococcus sp. (strain RHA1)
Length = 298
Score = 89.8 bits (213), Expect = 6e-17
Identities = 58/167 (34%), Positives = 96/167 (57%), Gaps = 1/167 (0%)
Frame = +2
Query: 185 IKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNP 364
I+ V VIG G+MG+GIA+V A+A +V + + + + A + I +L R K
Sbjct: 6 IQRVGVIGAGIMGAGIAEVCARAHVDVLVFEQTRELAAAGRSRILRSLDRGVSSG-KITE 64
Query: 365 QEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPS-HTIFA 541
+E E+ + R+ +D + + LVVEA+VE+ VK ++F +LD V + + A
Sbjct: 65 REREQ----AAWRLRFTSDLGDFA-DRQLVVEAVVEDEKVKSEIFTELDQVVTDPNAVLA 119
Query: 542 SNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEA 682
SNTSS+ I ++ K ++ G+HFFNPVPV+ L+ +V +TS++
Sbjct: 120 SNTSSIPIMKLGIATKSPERVIGMHFFNPVPVLPLVELVTTLKTSKS 166
>UniRef50_A0LI43 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=1; Syntrophobacter fumaroxidans MPOB|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB)
Length = 681
Score = 89.4 bits (212), Expect = 8e-17
Identities = 57/187 (30%), Positives = 96/187 (51%), Gaps = 1/187 (0%)
Frame = +2
Query: 170 AMQSAIKNVTVIGGGLMGSGIAQVSAQAGQ-NVTLVDVSNDALAKAKKSIGTNLSRVAKK 346
A AI V ++G GLM S +AQ+ + + V + D+S +AL K + R+ +K
Sbjct: 311 AKPGAIAKVGIVGAGLMASQLAQLFIERLEVPVVMKDISPEALEKGCGQVVEGFRRLGEK 370
Query: 347 MYKDNPQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPS 526
+ E G ++ D + S D V+EA+ E + VK ++ +L+ +
Sbjct: 371 -----GKLTEGKARHLAGLVSGTLDFRDFS-DCDFVIEAVFEEMAVKKQVLGELEPLLRP 424
Query: 527 HTIFASNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEW 706
+ A+NTSSLS+ E+ASV++ + G HFFNPV V+ L+ V++ ++TS T +
Sbjct: 425 DAVIATNTSSLSVTEMASVLRVPGRMLGFHFFNPVAVLPLVEVIRTAQTSGEALATAFDL 484
Query: 707 GKSXGKT 727
+ KT
Sbjct: 485 ARKLRKT 491
>UniRef50_Q39CK1 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=44;
Proteobacteria|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Burkholderia sp. (strain 383) (Burkholderia cepacia
(strain ATCC 17760/ NCIB 9086 / R18194))
Length = 710
Score = 89.0 bits (211), Expect = 1e-16
Identities = 56/181 (30%), Positives = 90/181 (49%)
Frame = +2
Query: 185 IKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNP 364
++ + V+GGG MG+GIA + AG VT+++ +LA+ + + + K
Sbjct: 304 VERIGVVGGGTMGAGIAVSALDAGLPVTMIERDEASLARGRAHVEKVYDGLVAKGRMTPA 363
Query: 365 QEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFAS 544
+ L R T + +A AD+V+EA+ E++ VK +F +L V + A+
Sbjct: 364 AHAAR-----LARFKGGT-SYDALAQADVVIEAVFEDMAVKKAVFAELARVCKPGAVLAT 417
Query: 545 NTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXGK 724
NTS L I+E+A+ + R GLHFF+P VM+LL +V + S T K K
Sbjct: 418 NTSYLDIDELAASIDRPADVIGLHFFSPANVMKLLEIVVPARVSADVVATAFALAKQLKK 477
Query: 725 T 727
T
Sbjct: 478 T 478
>UniRef50_A3N0P8 Cluster: Putative fatty acid oxidation complex
alpha subunit; n=1; Actinobacillus pleuropneumoniae
L20|Rep: Putative fatty acid oxidation complex alpha
subunit - Actinobacillus pleuropneumoniae serotype 5b
(strain L20)
Length = 705
Score = 89.0 bits (211), Expect = 1e-16
Identities = 49/181 (27%), Positives = 96/181 (53%), Gaps = 1/181 (0%)
Frame = +2
Query: 185 IKNVTVIGGGLMGSGIAQVSAQ-AGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDN 361
+ V+++G G MG+GIA ++A A V + D+ + KA ++ + + K ++
Sbjct: 315 VAQVSILGSGYMGAGIAYLTANNAKVPVRIKDIHPSEIRKALRTCFELMQKSTDKNQLNH 374
Query: 362 PQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFA 541
+ +++ + T + A+KS D V+EA+ E++ +K ++ + + TIFA
Sbjct: 375 GEMIQRM------NLITGGERLVAAKSTDFVIEAVYEDLKLKQRMLAESESYYSEQTIFA 428
Query: 542 SNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXG 721
+NTS+ +I +IA+ R + GLH+F+PV +++ ++ S T E T T + + G
Sbjct: 429 TNTSTFAIKDIAACAIRPENVIGLHYFSPVTTQKMVEIIPHSATGEHTIATAIHFAIQQG 488
Query: 722 K 724
K
Sbjct: 489 K 489
>UniRef50_Q8G825 Cluster: Possible butyryl-CoA dehydrogenase; n=2;
Bifidobacterium longum|Rep: Possible butyryl-CoA
dehydrogenase - Bifidobacterium longum
Length = 319
Score = 88.6 bits (210), Expect = 1e-16
Identities = 59/184 (32%), Positives = 91/184 (49%), Gaps = 4/184 (2%)
Frame = +2
Query: 185 IKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNP 364
IK + +G G MG I A AG V LV S +L KA K+I ++ A+ +
Sbjct: 8 IKTIANVGTGTMGHAITLQFALAGYPVHLVGRSEASLEKAMKAIRSD----AEDFAEAGL 63
Query: 365 QEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFAS 544
+ V+ L RI D A D V+E++ EN+ VK ++ +++ AP I ++
Sbjct: 64 LKAGDTVDTVLARITGYADYASGVADVDFVIESVAENLDVKKSVWTEVEHAAPKDAILST 123
Query: 545 NTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETS----EATYKTMMEWGK 712
NTS LS + SV+ ++F HF+NP +M L+ VV G +T + T+ M + GK
Sbjct: 124 NTSGLSPTALQSVMGHPERFVVAHFWNPAQLMPLVEVVPGEKTDPKVVDITFDLMAKIGK 183
Query: 713 SXGK 724
K
Sbjct: 184 KPAK 187
>UniRef50_Q08426 Cluster: Peroxisomal bifunctional enzyme (PBE)
(PBFE) [Includes: Enoyl-CoA
hydratase/3,2-trans-enoyl-CoA isomerase (EC 5.3.3.8) (EC
4.2.1.17); 3- hydroxyacyl-CoA dehydrogenase (EC
1.1.1.35)]; n=28; Euteleostomi|Rep: Peroxisomal
bifunctional enzyme (PBE) (PBFE) [Includes: Enoyl-CoA
hydratase/3,2-trans-enoyl-CoA isomerase (EC 5.3.3.8) (EC
4.2.1.17); 3- hydroxyacyl-CoA dehydrogenase (EC
1.1.1.35)] - Homo sapiens (Human)
Length = 723
Score = 88.6 bits (210), Expect = 1e-16
Identities = 60/186 (32%), Positives = 88/186 (47%)
Frame = +2
Query: 167 SAMQSAIKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKK 346
+A + +V V+G G MG GI A+A V VD + LA A K I + L + A K
Sbjct: 291 TASARPVSSVGVVGLGTMGRGIVISFARARIPVIGVDSDKNQLATANKMITSVLEKEASK 350
Query: 347 MYKDNPQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPS 526
M + + G T + + DLV+EA+ E + +K ++F +L V
Sbjct: 351 MQQSG--------HPWSGPKPRLTSSVKELGGVDLVIEAVFEEMSLKKQVFAELSAVCKP 402
Query: 527 HTIFASNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEW 706
+NTS+L ++EIAS R G HFF+P VM+LL V+ +S T T+M
Sbjct: 403 EAFLCTNTSALDVDEIASSTDRPHLVIGTHFFSPAHVMKLLEVIPSQYSSPTTIATVMNL 462
Query: 707 GKSXGK 724
K K
Sbjct: 463 SKKIKK 468
>UniRef50_Q83DW6 Cluster: Fatty oxidation complex, alpha subunit;
n=9; Gammaproteobacteria|Rep: Fatty oxidation complex,
alpha subunit - Coxiella burnetii
Length = 642
Score = 88.2 bits (209), Expect = 2e-16
Identities = 53/163 (32%), Positives = 88/163 (53%)
Frame = +2
Query: 188 KNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNPQ 367
+ + VIG G+MG IA A G VTL D S + +A A K A +Y +
Sbjct: 274 QQIHVIGAGVMGGDIAAWCALRGIRVTLHDKSAEKIAPAIKR--------AHALY-EKKL 324
Query: 368 EVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFASN 547
++ + + ++ R+ + K ADL++EA+ E+I VK ++ ++ I A+N
Sbjct: 325 KIPRLIQAAMDRLEPDVEGTGVKK-ADLIIEAVFEDIKVKQEVLSAIEPQLKPEAILATN 383
Query: 548 TSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETS 676
TSSLS++E++SV+K ++ +HFFNPV + L+ V +TS
Sbjct: 384 TSSLSLDELSSVLKNPERLVAIHFFNPVAKLPLVEVASSQQTS 426
>UniRef50_Q0EXX8 Cluster: Fatty oxidation complex, alpha subunit;
n=1; Mariprofundus ferrooxydans PV-1|Rep: Fatty
oxidation complex, alpha subunit - Mariprofundus
ferrooxydans PV-1
Length = 701
Score = 88.2 bits (209), Expect = 2e-16
Identities = 62/182 (34%), Positives = 93/182 (51%)
Frame = +2
Query: 179 SAIKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKD 358
+ ++ V G G+MG GIA V++Q+ +V L +V+ + L + K I R KK D
Sbjct: 307 ATMQKAAVYGAGVMGGGIAWVASQS-MDVDLHEVAAEPLGRGMKGIARLAMR--KKGRAD 363
Query: 359 NPQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIF 538
+ + L RI D + S D+V+EA++E+I VK +L+ L T+
Sbjct: 364 SKR---------LARIRPVLDESGLS-DVDVVIEAVLEDIRVKRRLWASLGKHVRKDTLL 413
Query: 539 ASNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSX 718
SNTSSLSI+++ + GLHFFNP P M L+ VV G +T+ T + S
Sbjct: 414 LSNTSSLSISDMQHRRANAGRIAGLHFFNPAPKMPLVEVVAGEKTTPETVDKVCALAVSW 473
Query: 719 GK 724
GK
Sbjct: 474 GK 475
>UniRef50_A6DTH3 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
C-terminal domain family protein; n=1; Lentisphaera
araneosa HTCC2155|Rep: 3-hydroxyacyl-CoA dehydrogenase,
C-terminal domain family protein - Lentisphaera araneosa
HTCC2155
Length = 762
Score = 87.8 bits (208), Expect = 2e-16
Identities = 56/181 (30%), Positives = 95/181 (52%), Gaps = 3/181 (1%)
Frame = +2
Query: 179 SAIKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKD 358
S IK++ V+G G+MGS IA A G +V L+D+++ + S G KK+ K
Sbjct: 2 SKIKHIAVLGSGVMGSQIAAHFANCGFSVALLDLTSAGPKPSAISEGA-----VKKLLKI 56
Query: 359 NPQEV-EKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTI 535
NP + V +++ N D E ADL++EA++E++ +K L+ Q+ + I
Sbjct: 57 NPSPLYSPSVIENIFPGNF-DDHLEHLDEADLIIEAVIEDLAIKQNLWSQICKYVKADAI 115
Query: 536 FASNTSSLSINEIASVVKRKD--KFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWG 709
A+NTS L + +I + K +F G+HFFNP +LL ++ G +T + + E+
Sbjct: 116 LATNTSGLPLKDITKNLSNKSLKRFLGVHFFNPPRYQKLLELIPGPKTQDGLLEEFAEFA 175
Query: 710 K 712
+
Sbjct: 176 R 176
>UniRef50_Q988C8 Cluster: 3-hydroxybutyryl-coA dehydrogenase; n=1;
Mesorhizobium loti|Rep: 3-hydroxybutyryl-coA
dehydrogenase - Rhizobium loti (Mesorhizobium loti)
Length = 309
Score = 87.4 bits (207), Expect = 3e-16
Identities = 50/179 (27%), Positives = 92/179 (51%)
Frame = +2
Query: 185 IKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNP 364
I+N+ +IG G MG G+A A+ G V DV+ A+ +A+ + V + P
Sbjct: 2 IRNIAIIGLGTMGPGMAARLARGGLQVVAYDVAPAAIERARSMLSV-AETVLDALGIALP 60
Query: 365 QEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFAS 544
+G + D +A ADLV+E + ENI +K +++ +DG+ TI AS
Sbjct: 61 SA-------GVGTVRFTDDIGDAVSGADLVIENVPENISIKADVYRTIDGLIGQDTIVAS 113
Query: 545 NTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXG 721
+TS + I ++ + + ++ G+H+ NP ++ ++ V+ G +T+ T T+ + +S G
Sbjct: 114 DTSGIPITKLQAHISYPERMVGMHWSNPPHIIPMIEVIAGEKTAPQTVATIRDLIRSIG 172
>UniRef50_Q68WH7 Cluster: Putative fatty acid oxidation complex
trifunctional enzyme [Includes: 3-hydroxyacyl-CoA
dehydrogenase (EC 1.1.1.35); Enoyl-CoA
hydratase/Delta(3)-cis-Delta(2)-trans-enoyl-CoA
isomerase (EC 4.2.1.17) (EC 5.3.3.8)]; n=20;
Rickettsia|Rep: Putative fatty acid oxidation complex
trifunctional enzyme [Includes: 3-hydroxyacyl-CoA
dehydrogenase (EC 1.1.1.35); Enoyl-CoA
hydratase/Delta(3)-cis-Delta(2)-trans-enoyl-CoA
isomerase (EC 4.2.1.17) (EC 5.3.3.8)] - Rickettsia typhi
Length = 720
Score = 87.4 bits (207), Expect = 3e-16
Identities = 67/196 (34%), Positives = 99/196 (50%), Gaps = 7/196 (3%)
Frame = +2
Query: 173 MQSAIKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDV----SNDALAKAKKSIGTNLSRVA 340
MQ+ IK V VIG G+MGSGIA + A + V L+D+ SND K ++ NL R
Sbjct: 1 MQNEIKKVCVIGAGVMGSGIAALIANSSHRVVLLDILDKDSNDPNKIVKNAV-KNLHR-Q 58
Query: 341 KKMYKDNPQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVA 520
K P +V F+ ++G + D K +LV+E IVE + +KH+L+ ++
Sbjct: 59 KLPPLSYPDKVN-FI--TIGNLEHDLDLI---KECNLVIEVIVEKLDIKHQLYNKIIPYL 112
Query: 521 PSHTIFASNTSSLSINEIASVVKR--KDKFGGLHFFNPVPVMRLL-XVVKGSETSEATYK 691
TI ASNTS+L + ++ + K +F HFFNP M L+ ++ + E K
Sbjct: 113 KEDTIIASNTSTLPLKKLKENLPNNIKSRFIITHFFNPPRYMELVELIIDNTIKDEVIEK 172
Query: 692 TMMEWGKSXGKTCITC 739
+ K GKT I C
Sbjct: 173 ISVFLTKILGKTIIKC 188
>UniRef50_A6UH30 Cluster: 3-hydroxybutyryl-CoA epimerase; n=2;
Sinorhizobium|Rep: 3-hydroxybutyryl-CoA epimerase -
Sinorhizobium medicae WSM419
Length = 442
Score = 87.0 bits (206), Expect = 4e-16
Identities = 54/170 (31%), Positives = 85/170 (50%)
Frame = +2
Query: 185 IKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNP 364
I++ VIGGG MG+GIA AG + +V+ A A + K+
Sbjct: 44 IRSAAVIGGGTMGTGIAAALCNAGLPLVIVERDEAAREGAVARLRAIFDGAVKRRRISAG 103
Query: 365 QEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFAS 544
E+ L R+ ATD A ++ ADL++EA+ E++ VK +F+++ + A+
Sbjct: 104 LAAER-----LARVTGATDYAVLAE-ADLIIEAVFEDLDVKRDVFRKVAAACRHDAVLAT 157
Query: 545 NTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKT 694
NTS L+ IA + ++F GLHFF+P VM+LL +V T+ T
Sbjct: 158 NTSYLNPERIADGIASPERFLGLHFFSPAQVMKLLEIVPTGATAPEALAT 207
>UniRef50_A3TT55 Cluster: Putative fatty acid oxidation complex
alpha subunit; n=3; Rhodobacterales|Rep: Putative fatty
acid oxidation complex alpha subunit - Oceanicola
batsensis HTCC2597
Length = 686
Score = 87.0 bits (206), Expect = 4e-16
Identities = 59/179 (32%), Positives = 85/179 (47%)
Frame = +2
Query: 149 RNFSNSSAMQSAIKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNL 328
R +S + I +V VIG G MG IA +A G+ VT+ DV+ D L G +
Sbjct: 305 RRLKSSGGREDGIAHVHVIGAGAMGGEIAAWAAMQGKRVTIEDVALDPL-------GETI 357
Query: 329 SRVAKKMYKDNPQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQL 508
R + + +EK D+L R+ D ++ ADLV+EA E G+K ++ +L
Sbjct: 358 RRATRVYDGKHLSGIEK--RDALDRLMPDPDRLGRAR-ADLVIEAAPEKPGLKEDIYAEL 414
Query: 509 DGVAPSHTIFASNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEAT 685
I A+NTSSL + + +F GLHFFNPV M L+ +V S T
Sbjct: 415 TDAMKPGAILATNTSSLPLASLVDAAPDPARFAGLHFFNPVSKMPLVEIVSHDMASTET 473
>UniRef50_A5IPA0 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor; n=14; Staphylococcus|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding precursor -
Staphylococcus aureus subsp. aureus JH9
Length = 753
Score = 86.6 bits (205), Expect = 6e-16
Identities = 58/172 (33%), Positives = 90/172 (52%), Gaps = 6/172 (3%)
Frame = +2
Query: 185 IKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNP 364
I VTV+G G MG+ +A + AG V L+D+ D + + +AKK Y
Sbjct: 3 INKVTVLGAGTMGAQLAALFVNAGLKVKLLDIVVDK---------NDPNLIAKKSYDKIT 53
Query: 365 QEVEKFVNDSLGRINTAT----DAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHT 532
+ + D L ++ T D + ADL +EA+ E+I +KH +++Q+ A
Sbjct: 54 DKKRPLLFD-LNLVSHLTYGNFDDDLVNDDADLYIEAVKEDIEIKHAVWQQVLQHAKEDA 112
Query: 533 IFASNTSSLSINEIASVVKRKD--KFGGLHFFNPVPVMRLLXVVKGSETSEA 682
+FA+NTS + IN IA KD +F GLHFFNP +M+L+ ++ S T E+
Sbjct: 113 LFATNTSGIPINAIAQAFNEKDQERFFGLHFFNPPRIMKLVELIPTSHTKES 164
>UniRef50_A6FFH1 Cluster: Probable 3-hydroxyacyl-CoA dehydrogenase;
n=1; Moritella sp. PE36|Rep: Probable 3-hydroxyacyl-CoA
dehydrogenase - Moritella sp. PE36
Length = 698
Score = 86.2 bits (204), Expect = 7e-16
Identities = 60/180 (33%), Positives = 94/180 (52%)
Frame = +2
Query: 194 VTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNPQEV 373
V V+G G+MG+GIA A G V L D+S + AK + L+ K+ ++
Sbjct: 316 VGVLGAGMMGAGIAYALASHGITVILKDISLEKAVFAKSYTASILANC--KL-----EDE 368
Query: 374 EKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFASNTS 553
EK L RI + ++A+ D+V+EA+ E+ VK++ ++ I ASNTS
Sbjct: 369 EKCT--ILQRITPSKESADLI-GCDMVIEAVFEDRKVKNQAITEILTAVGDELIMASNTS 425
Query: 554 SLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXGKTCI 733
+L I+ +A+ + + F GLHFF+PV M L+ ++KG +TS AT + GK I
Sbjct: 426 TLPISSLATASTKPENFIGLHFFSPVDKMPLVEIIKGDKTSSATLAAAYDLVIQIGKVPI 485
>UniRef50_Q93HI5 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=2;
Actinomycetales|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Streptomyces avermitilis
Length = 272
Score = 85.8 bits (203), Expect = 1e-15
Identities = 53/165 (32%), Positives = 89/165 (53%), Gaps = 1/165 (0%)
Frame = +2
Query: 215 LMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNPQEVEKFVNDS 394
+MG+G+A+V A+AG +V + D LA+ + + +L+ +K D + + ++
Sbjct: 1 MMGAGLAEVCARAGLDVLVTSSGEDGLARGRGRLERSLAHAVRK---DRISDTAR--EET 55
Query: 395 LGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLD-GVAPSHTIFASNTSSLSINE 571
L R++ TD A A + LV+EA E+ K ++F+ LD V I A+NTS+L +
Sbjct: 56 LARVSFTTDLA-AFRDRQLVLEAAPEDEPTKLRIFQALDRAVEDPEAILATNTSALPVMR 114
Query: 572 IASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEW 706
+A R + GLHFFNP PV+ L+ V+ T + T + E+
Sbjct: 115 LARATDRPGQVLGLHFFNPAPVLPLVEVIGSLLTRDRTRRIAAEF 159
>UniRef50_Q4FL01 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3;
Bacteria|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Pelagibacter ubique
Length = 740
Score = 85.8 bits (203), Expect = 1e-15
Identities = 65/191 (34%), Positives = 93/191 (48%), Gaps = 6/191 (3%)
Frame = +2
Query: 185 IKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNP 364
IK V VIG G MGSGIA A VTL+D+ + +A+ K+YK P
Sbjct: 3 IKKVVVIGSGTMGSGIAAHLCNANIPVTLLDLKTEISEQARD-----------KIYKSRP 51
Query: 365 Q---EVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTI 535
+ K N +G I D + K AD VVEA+VE I +KH ++K++ I
Sbjct: 52 PLLLDKSKIKNIKVGNI---LDNFDEVKEADWVVEAVVERIDIKHDIYKKIFKERKKGAI 108
Query: 536 FASNTSSLSINEIASVVKRKDK--FGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWG 709
+SNTSS+ I ++ + ++K F HFFNPV M LL +VK ++ +
Sbjct: 109 VSSNTSSIPIKILSQHLSEEEKKDFCITHFFNPVRYMGLLEIVKNENNDLDKINSLKAFC 168
Query: 710 KS-XGKTCITC 739
++ GK I C
Sbjct: 169 ETELGKGAIIC 179
>UniRef50_Q0LZ25 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Caulobacter sp. K31|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Caulobacter sp. K31
Length = 296
Score = 85.8 bits (203), Expect = 1e-15
Identities = 62/180 (34%), Positives = 91/180 (50%), Gaps = 3/180 (1%)
Frame = +2
Query: 194 VTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSR-VAKKMYKDNPQE 370
+ V+G GLMG+ IA V A G +V L D AL KA + L R V++ +Y + +
Sbjct: 18 IGVVGAGLMGAEIALVFALGGMDVLLHDRDAAALEKALARLSALLDRGVSRGLYTEGRRA 77
Query: 371 VEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFASNT 550
+L I A D + DLV EA+ E++ VK ++ LD P + ASNT
Sbjct: 78 T------ALENIRLAPDLSRFG-DRDLVTEAVFESLEVKGQVLAALDEACPEACVIASNT 130
Query: 551 SSLSINEIASVV--KRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXGK 724
S+L I+ + + + +R+ +F G H+F+PV M L+ VV ETS T K GK
Sbjct: 131 STLPISTLGAALSPERRPRFLGAHYFSPVSRMLLVEVVPAFETSPETVAWTTSLLKRIGK 190
>UniRef50_A5VHQ1 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor; n=2; Lactobacillus reuteri|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding precursor -
Lactobacillus reuteri F275
Length = 294
Score = 85.8 bits (203), Expect = 1e-15
Identities = 52/165 (31%), Positives = 92/165 (55%), Gaps = 1/165 (0%)
Frame = +2
Query: 185 IKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNP 364
+KN+ + G G++GS IA +A +G NV+ V N + A++ I + K Y+ +
Sbjct: 1 MKNIMIAGAGVLGSQIAYQTALSGFNVS---VYNHHIDTAERRI-----KALKSDYERDL 52
Query: 365 QEVEKFVNDSLGRINTATD-AAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFA 541
+K L I TD A A K ADL++EA+ E++ +K + ++++ +AP TIFA
Sbjct: 53 HLTDKEFQQGLNNIKVITDDVATAVKDADLMIEALPESLELKEQFYEEVSELAPEKTIFA 112
Query: 542 SNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETS 676
SN+S+ +++A R +KF +HF N + ++ ++ S+TS
Sbjct: 113 SNSSTFIPSQLAPYTDRPEKFLNMHFANQIWKFNVVEIMGTSQTS 157
>UniRef50_A0LDJ8 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=1; Magnetococcus sp. MC-1|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Magnetococcus sp. (strain MC-1)
Length = 717
Score = 85.0 bits (201), Expect = 2e-15
Identities = 54/163 (33%), Positives = 87/163 (53%)
Frame = +2
Query: 188 KNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNPQ 367
++V V+G G+MG IA A G V+L +S + L +A + T L+R +
Sbjct: 310 RHVHVVGDGVMGRAIAVWCALQGMQVSLQGLSTELLGRALQE-ATQLARKKRLDRLATRD 368
Query: 368 EVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFASN 547
+++ + D G + ADLV+EAI E++ K +L+ L+ H + A+N
Sbjct: 369 LLDRLMPDQRG---------DGVCHADLVIEAIFEDVTAKQQLYAALEPRMREHALLATN 419
Query: 548 TSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETS 676
TS++ + +A +KR + GLHFFNPV M L+ VV+G +TS
Sbjct: 420 TSAIPLQTLAQGLKRPQQLLGLHFFNPVARMPLVEVVEGPQTS 462
>UniRef50_A3U7V8 Cluster: 3-hydroxyacyl-CoA dehydrogenase/enoyl-CoA
hydratase/isomerasefamily protein; n=19; Bacteria|Rep:
3-hydroxyacyl-CoA dehydrogenase/enoyl-CoA
hydratase/isomerasefamily protein - Croceibacter
atlanticus HTCC2559
Length = 802
Score = 83.0 bits (196), Expect = 7e-15
Identities = 63/197 (31%), Positives = 94/197 (47%), Gaps = 14/197 (7%)
Frame = +2
Query: 185 IKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSR--VAKKMYKD 358
I + VIG G+MGSGIA A G V L+D+ L + +K+ G L V ++ D
Sbjct: 6 INKIAVIGSGIMGSGIACHFANIGVEVLLLDIVPRELNEKEKAKGLTLEDKVVRNRIVND 65
Query: 359 NPQEVEK------FVNDSLGRINTAT--DAAEASKSADLVVEAIVENIGVKHKLFKQLDG 514
Q K + D RI+T D K D ++E +VE + +K ++F+ L+
Sbjct: 66 ALQSSIKSKPAPLYHKDFASRISTGNLEDDIAKVKDVDWIIEVVVERLDIKKQVFENLEK 125
Query: 515 VAPSHTIFASNTSSLSINEIASVVKRKD---KFGGLHFFNPVPVMRLLXVVKGSETSEAT 685
T+ SNTS + IN + S + +D F G HFFNP + L ++ G +TS
Sbjct: 126 HRTEGTLITSNTSGIPIN-LMSEGRSEDFQKHFCGTHFFNPPRYLELFEIIPGPKTSPEV 184
Query: 686 YKTMMEWG-KSXGKTCI 733
+ +G K GKT I
Sbjct: 185 LDFLNGYGEKFLGKTSI 201
>UniRef50_Q9HJM0 Cluster: Beta-hydroxybutyryl-CoA dehydrogenase
related protein; n=3; Thermoplasmatales|Rep:
Beta-hydroxybutyryl-CoA dehydrogenase related protein -
Thermoplasma acidophilum
Length = 314
Score = 82.2 bits (194), Expect = 1e-14
Identities = 69/195 (35%), Positives = 99/195 (50%), Gaps = 25/195 (12%)
Frame = +2
Query: 185 IKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNP 364
IK V VIG G MGS IA++ A G NV + D + D LA++ S + K++ + P
Sbjct: 3 IKTVGVIGAGTMGSAIAELFAFNGFNVVMKDQNMD-LARSGYSGIEKILNDMKRINDEKP 61
Query: 365 QE----VEKF---------------------VNDSLGRINTATDAAEASKSADLVVEAIV 469
++ +E + VN L RI+ TD S DLV+EA
Sbjct: 62 EKEIARIENYGIKLSDDQKNAIRKKIGVQVDVNAMLKRISL-TDKYSDLSSCDLVIEAAF 120
Query: 470 ENIGVKHKLFKQLDGVAPSHTIFASNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLL 649
EN VK+++F + ++ H I ASNTSSLSI E++S +KR + LHFFNP ++ L+
Sbjct: 121 ENQDVKNRIFSDISDLS-EHAIIASNTSSLSITEMSSRLKRPENALILHFFNPPYLLPLV 179
Query: 650 XVVKGSETSEATYKT 694
VV TS+ T
Sbjct: 180 EVVPSLYTSDEAKNT 194
>UniRef50_Q14G85 Cluster: Fusion product of 3-hydroxacyl-CoA
dehydrogenase and acyl-CoA-binding protein; n=11;
Francisella tularensis|Rep: Fusion product of
3-hydroxacyl-CoA dehydrogenase and acyl-CoA-binding
protein - Francisella tularensis subsp. tularensis
(strain FSC 198)
Length = 898
Score = 80.2 bits (189), Expect = 5e-14
Identities = 57/175 (32%), Positives = 87/175 (49%), Gaps = 4/175 (2%)
Frame = +2
Query: 164 SSAMQSAIKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAK 343
S + + AI + V+G G MG+ IA A A V L D+ + A I +L+++ K
Sbjct: 110 SKSQRKAIDKIAVLGAGTMGAQIAAHFANAKFPVVLFDLKSQQ-GSANVIIEDSLAKLTK 168
Query: 344 KMYKDNPQEVEKFVNDSLGRINTAT--DAAEASKSADLVVEAIVENIGVKHKLFKQLDGV 517
NP DS+ I A D E DL++EA+ E I +K L+ ++
Sbjct: 169 L----NPAPFGS--KDSIKYITPANYEDNLELLADCDLIIEAVAERIDIKESLYTKISSH 222
Query: 518 APSHTIFASNTSSLSINEIASVVKR--KDKFGGLHFFNPVPVMRLLXVVKGSETS 676
+ I ASNTS LSI ++A V+ K F G+HFFNP M L+ ++ ++T+
Sbjct: 223 IKENAILASNTSGLSITKLAQVLPENLKVNFCGVHFFNPPRYMPLVELIPHADTN 277
>UniRef50_A6GBG1 Cluster: 3-hydroxyacyl-CoA dehydrogenase/enoyl-CoA
hydratase/isomerase family protein; n=1; Plesiocystis
pacifica SIR-1|Rep: 3-hydroxyacyl-CoA
dehydrogenase/enoyl-CoA hydratase/isomerase family
protein - Plesiocystis pacifica SIR-1
Length = 789
Score = 80.2 bits (189), Expect = 5e-14
Identities = 58/180 (32%), Positives = 90/180 (50%), Gaps = 6/180 (3%)
Frame = +2
Query: 218 MGSGIAQVSAQAGQNVTLVDVSNDAL-AKAKKSIGTNLSRVA-KKMYKDNPQEV-EKFVN 388
MG+GIA A AG L+D+ + A A K+ L+ A K + K P + K
Sbjct: 1 MGAGIAAHLANAGIRTYLLDIVPRGVDADAPKAARNKLAAGALKALPKAKPPALMNKAFA 60
Query: 389 DSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFASNTSSLSIN 568
+ N D A +D+V+EAI+E + +K +FK++ A TI ASNTS + I
Sbjct: 61 GRITAGNFDDDLERAVAESDIVIEAIIERLDIKQTVFKKVAAAAKETTILASNTSGIPIA 120
Query: 569 EIASVVKR--KDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWG-KSXGKTCITC 739
+IA + +++F GLHFFNP M LL V+ T++ + ++ + GK + C
Sbjct: 121 DIAEALDEGARERFLGLHFFNPPRWMHLLEVIPSKYTAKKYVDEVAKFSDEVLGKGVVLC 180
>UniRef50_Q5KVJ3 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=16;
Bacillaceae|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Geobacillus kaustophilus
Length = 795
Score = 79.4 bits (187), Expect = 9e-14
Identities = 58/192 (30%), Positives = 90/192 (46%), Gaps = 12/192 (6%)
Frame = +2
Query: 173 MQSAIKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNL------SR 334
M I+ V+G G+MGSGIA A G L+D+ L K +++ G L +R
Sbjct: 1 MVKRIRRAAVLGSGVMGSGIAAHLANVGIPTLLLDIVPRELTKEEEAKGWTLEHKQVRNR 60
Query: 335 VA----KKMYKDNPQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFK 502
+A +++ K P + N +L D D ++EA+VE + VK ++F
Sbjct: 61 LANQALERLLKQKPAPLMSKDNIALIETGNFEDDFHRLAEVDWIIEAVVEKLEVKKEVFA 120
Query: 503 QLDGVAPSHTIFASNTSSLSINEIASVVKR--KDKFGGLHFFNPVPVMRLLXVVKGSETS 676
++D V TI +SNTS +SI +A K F G HFFNP ++LL ++ T
Sbjct: 121 RVDEVRTPGTIVSSNTSGISIAAMAEGRSDDFKKHFLGTHFFNPPRYLKLLEIIPTEHTD 180
Query: 677 EATYKTMMEWGK 712
M +G+
Sbjct: 181 PDVVAYMKSFGE 192
>UniRef50_A4FJS5 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=1; Saccharopolyspora erythraea NRRL
2338|Rep: 3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Saccharopolyspora erythraea (strain NRRL 23338)
Length = 659
Score = 79.4 bits (187), Expect = 9e-14
Identities = 58/180 (32%), Positives = 87/180 (48%)
Frame = +2
Query: 185 IKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNP 364
I+ V V+G G MG+GIA+ AG +V LVD AL +A
Sbjct: 281 IRTVGVVGAGTMGAGIARAFVSAGADVALVDRDPAALERAA------------------- 321
Query: 365 QEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFAS 544
+V + D+ R+ T T A + ADLVVEA+VE+ GVK + ++ GV A+
Sbjct: 322 DQVARAGRDAAARLRTGT-ALDLLSDADLVVEAVVEDHGVKAAVLGEVAGVVRPGLPLAT 380
Query: 545 NTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXGK 724
NTS L I+ +A+ ++ G+HF P +L VV+G TS+ ++ + GK
Sbjct: 381 NTSYLDIDALAATAADPERVLGMHFLAPAHRTGVLEVVRGRATSQDALDHVLSAARLLGK 440
>UniRef50_Q7D836 Cluster: 3-hydroxyacyl-CoA dehydrogenase family
protein; n=8; Mycobacterium tuberculosis complex|Rep:
3-hydroxyacyl-CoA dehydrogenase family protein -
Mycobacterium tuberculosis
Length = 304
Score = 79.0 bits (186), Expect = 1e-13
Identities = 56/162 (34%), Positives = 82/162 (50%)
Frame = +2
Query: 200 VIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNPQEVEK 379
V+G GLMG IA V A AG +V + D + + L A +RVA
Sbjct: 12 VVGAGLMGRRIAGVLASAGLDVAITDTNAEILHAA----AVEAARVA------------- 54
Query: 380 FVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFASNTSSL 559
G + A D A A ADLV+EA+VEN+ VK +LF++L +AP + A+NTS L
Sbjct: 55 --GAGRGSVAAAADLAAAIPDADLVIEAVVENLAVKQELFERLATLAPD-AVLATNTSVL 111
Query: 560 SINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEAT 685
I + V+ + G HF+NP ++ ++ VV + T+ T
Sbjct: 112 PIGAVTERVEDGSRVIGTHFWNPPDLIPVVEVVPSARTAPDT 153
>UniRef50_Q0LRY2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
precursor; n=2; Alphaproteobacteria|Rep:
3-hydroxybutyryl-CoA dehydrogenase precursor -
Caulobacter sp. K31
Length = 348
Score = 79.0 bits (186), Expect = 1e-13
Identities = 59/180 (32%), Positives = 88/180 (48%)
Frame = +2
Query: 194 VTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNPQEV 373
V V+G GLMG+GIA+V A G V L D D A + I ++ V D ++V
Sbjct: 49 VAVLGAGLMGAGIAKVFAAKGYPVFLFDRDLDTATSATRQINGAIAHV------DGGRDV 102
Query: 374 EKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFASNTS 553
D+ G + AEA A V E++ E + VK ++F L A + ASNTS
Sbjct: 103 -----DAAGSL------AEAVADAAFVFESVSEKLDVKRRIFSALAECARHDAVLASNTS 151
Query: 554 SLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXGKTCI 733
++ I +IA + + + G H++NP V+ L+ VV G T + MM+ S GK +
Sbjct: 152 AIPITQIAEGLPCEARIVGSHWWNPADVVPLVEVVPGIATDAHHVEAMMQLLISVGKKAV 211
>UniRef50_Q092W5 Cluster: 3-hydroxyacyl-CoA dehydrogenase/enoyl-CoA
hydratase/isomerase family protein; n=2;
Cystobacterineae|Rep: 3-hydroxyacyl-CoA
dehydrogenase/enoyl-CoA hydratase/isomerase family
protein - Stigmatella aurantiaca DW4/3-1
Length = 797
Score = 79.0 bits (186), Expect = 1e-13
Identities = 64/191 (33%), Positives = 99/191 (51%), Gaps = 11/191 (5%)
Frame = +2
Query: 173 MQSAIKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDV-------SNDALAKA--KKSIGTN 325
M + I+ V V+G G+MGSGIA A +G L+D+ D +KA K +
Sbjct: 1 MTTRIRKVAVLGAGVMGSGIAAHLANSGVRALLLDIVPPKAGPGEDTSSKAFRNKFVLGA 60
Query: 326 LSRVAKKMYKDNPQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQ 505
L+ + K+ K +P E+ V SL N D A ++ D V+E + E++ VK LF++
Sbjct: 61 LANLRKQ--KPSPIVSEQ-VFASLEVGNLEDDIARIAE-CDWVIEVVKEDLAVKQALFEK 116
Query: 506 LDGVAPSHTIFASNTSSLSINEIASV--VKRKDKFGGLHFFNPVPVMRLLXVVKGSETSE 679
++ I +SNTS LSI + + + +F HFFNPV M+LL +V G ET
Sbjct: 117 VEKHLRKDAIVSSNTSGLSIAGMLQGRGPEFRKRFLVTHFFNPVRYMKLLELVAGPETDP 176
Query: 680 ATYKTMMEWGK 712
A +T+ +G+
Sbjct: 177 AVVRTLHAFGE 187
>UniRef50_O29090 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Archaeoglobus fulgidus|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Archaeoglobus fulgidus
Length = 312
Score = 78.6 bits (185), Expect = 1e-13
Identities = 61/180 (33%), Positives = 93/180 (51%), Gaps = 3/180 (1%)
Frame = +2
Query: 194 VTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAK-KSIGTNLSRV--AKKMYKDNP 364
+ VIG G MG+ IA + A AG VTLVD S AL +A+ + G +L + A +DNP
Sbjct: 5 IAVIGAGTMGAAIALLFANAGFEVTLVDKSRGALRRAEDRHRGESLEELEEAGLRKQDNP 64
Query: 365 QEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFAS 544
+ + + R+ D +VEAIVE + K +LF++++ + S + A+
Sbjct: 65 ASLITYTTEL--RV----------YECDFIVEAIVERLRDKIELFRKIEEI-NSPAVLAT 111
Query: 545 NTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXGK 724
NTSS +EIA + ++ HF NP P++ L V G S+ T + +E KS GK
Sbjct: 112 NTSSFMPSEIARHLANPERLTLFHFSNP-PILMPLVEVGGEIVSDETVERAVEMAKSIGK 170
>UniRef50_Q8FRN7 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenase;
n=1; Corynebacterium efficiens|Rep: Putative
3-hydroxyacyl-CoA dehydrogenase - Corynebacterium
efficiens
Length = 755
Score = 78.2 bits (184), Expect = 2e-13
Identities = 51/173 (29%), Positives = 86/173 (49%), Gaps = 2/173 (1%)
Frame = +2
Query: 173 MQSAIKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMY 352
M S I VIG G MG+GIA + A AG VTL+D + + + L R ++
Sbjct: 8 MTSQINQAVVIGAGSMGAGIATLLANAGITVTLLDRHSGDPEDPNRLAESGLERQIQRGA 67
Query: 353 KDNPQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHT 532
P+ + ++ D A AD ++EA+ E++ VKH F+ ++ +
Sbjct: 68 FYRPEFSSRIQTGNI------VDDTAALTRADWIIEAVFEDLTVKHDTFRLIEEHRSPGS 121
Query: 533 IFASNTSSLSINEIASVV--KRKDKFGGLHFFNPVPVMRLLXVVKGSETSEAT 685
+ +SNTS++ + ++ V+ + F +HFFNP MRL+ +V G +T+ T
Sbjct: 122 LVSSNTSTIPLAQLTEVMGTPMRLDFAIVHFFNPPTTMRLVELVTGPDTTPKT 174
>UniRef50_A3VIL7 Cluster: Enoyl-CoA
hydratase/isomerase:3-hydroxyacyl-CoA dehydrogenase,3-
hydroxyacyl-CoA dehydrogenase, NAD-binding; n=1;
Rhodobacterales bacterium HTCC2654|Rep: Enoyl-CoA
hydratase/isomerase:3-hydroxyacyl-CoA dehydrogenase,3-
hydroxyacyl-CoA dehydrogenase, NAD-binding -
Rhodobacterales bacterium HTCC2654
Length = 695
Score = 78.2 bits (184), Expect = 2e-13
Identities = 49/180 (27%), Positives = 82/180 (45%)
Frame = +2
Query: 185 IKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNP 364
+ +V V+G G + +A + +AG VT+ + A+ + + I +
Sbjct: 299 VSSVGVVGAGALARDVAMAALKAGVPVTVALEDDTAITRVRGRIERAFGDAVEAGTLSGR 358
Query: 365 QEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFAS 544
+ +D L R+NTA D A D+++EA+ E+ K + QL VA HTIFAS
Sbjct: 359 ER-----DDRLRRLNTADDYG-ALDDKDVIIEALAEDSVRKTQALGQLSQVAAGHTIFAS 412
Query: 545 NTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXGK 724
+T+ I +A R D+F +HF P RL+ + T T++ ++ GK
Sbjct: 413 STAECDIETLAGASGRPDRFAAMHFIAPADANRLVEIAPARGTRPEALMTLIRLARAMGK 472
>UniRef50_Q46MP3 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=4;
Burkholderiales|Rep: 3-hydroxybutyryl-CoA dehydrogenase
- Ralstonia eutropha (strain JMP134) (Alcaligenes
eutrophus)
Length = 304
Score = 77.8 bits (183), Expect = 3e-13
Identities = 55/183 (30%), Positives = 88/183 (48%)
Frame = +2
Query: 179 SAIKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKD 358
S+ V V+G GLMG GIA + +V + D + A ++ I +L +
Sbjct: 6 SSRARVAVLGAGLMGHGIALAFMTSDFDVAIWDPVSQAREAVRERIAEHLELMG------ 59
Query: 359 NPQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIF 538
+P+ V+ + + + + D+VVEA E++ K +L +++D + S I
Sbjct: 60 DPRGVD---------VRVCSTLQDCVRDCDIVVEAAPESVSTKRELIREID-LVNSECII 109
Query: 539 ASNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSX 718
ASNTS L I EIA + G H++NP +M L+ VV+G T E K + +W
Sbjct: 110 ASNTSVLRITEIAEGSADPGRVVGTHWWNPPYLMPLVEVVRGELTREGVAKQVSQWLSKA 169
Query: 719 GKT 727
GKT
Sbjct: 170 GKT 172
>UniRef50_Q02A28 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Solibacter usitatus Ellin6076|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Solibacter usitatus (strain Ellin6076)
Length = 309
Score = 77.8 bits (183), Expect = 3e-13
Identities = 57/176 (32%), Positives = 90/176 (51%)
Frame = +2
Query: 200 VIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNPQEVEK 379
VIG G+MG GIA A G TL+ A A+ + L RV + QE+
Sbjct: 8 VIGTGMMGPGIALTLALGGVQTTLLS-RTPAGAERGVAEARRLGRVLVE------QELAA 60
Query: 380 FVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFASNTSSL 559
++ + +TD + AD+V+E+ E +G K +LF ++D VA + + ASNTS L
Sbjct: 61 ALDLDIAG---STDFEYSIGQADIVIESGPEEMGWKQELFARMDRVARADAVLASNTSGL 117
Query: 560 SINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXGKT 727
S+ IA+ R ++ HF+NP ++ L+ +++G TS A + E + GKT
Sbjct: 118 SVTAIAAECARPEQVLATHFWNPPHLVPLVEIIQGRATSPAAAAAVRELLTACGKT 173
>UniRef50_A1CC71 Cluster: 3-hydroxyacyl-CoA dehydrogenase, putative;
n=2; Aspergillus|Rep: 3-hydroxyacyl-CoA dehydrogenase,
putative - Aspergillus clavatus
Length = 307
Score = 77.8 bits (183), Expect = 3e-13
Identities = 53/176 (30%), Positives = 87/176 (49%)
Frame = +2
Query: 194 VTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNPQEV 373
V VIGGG++G + + A AG V L + S + A K I L + A K+ +
Sbjct: 16 VAVIGGGVLGRRLCMMWAAAGHTVQLYEKSPEVAVAALKYIHEALPQQASKLL------L 69
Query: 374 EKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFASNTS 553
K +G ++ A+ A ++A +V+EAI E + +K +LF QLD +AP+ I A+N+S
Sbjct: 70 GKKAGHGIGHVSPASSLETAVQNAWMVIEAIPELLPLKIELFGQLDQLAPADCILATNSS 129
Query: 554 SLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXG 721
S E+ V R+ + H++ P P L ++ T A ++E + G
Sbjct: 130 SYKSREMLEKVARRARVCNAHYYMP-PEQNHLEIMTCGFTDPAIISFLLEQAAAAG 184
>UniRef50_A7S4Z9 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 310
Score = 77.4 bits (182), Expect = 3e-13
Identities = 53/185 (28%), Positives = 92/185 (49%)
Frame = +2
Query: 173 MQSAIKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMY 352
MQ +V VIG GLMG+ IA A G V L D S A+ K+K+ + ++ +
Sbjct: 1 MQQEEPSVAVIGAGLMGTCIAGELAYHGARVNLYDRSAQAMEKSKEMLIQQKEQLKR--- 57
Query: 353 KDNPQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHT 532
+EV +D +G + EA ++ L+ EA +EN+ VK +FK + ++
Sbjct: 58 ----EEVMA-TSDFIGTVAFCESLEEAVVNSGLIFEATIENLEVKKSVFKSISQFCRTNA 112
Query: 533 IFASNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGK 712
+ A+NT +L + +A V ++ G+ F PV + + + GS+TS T + + ++ +
Sbjct: 113 VIATNTLALDTSVVAEHVTNPERCLGIRFLYPVYSIPEVEITLGSQTSPETIQKVQQFLE 172
Query: 713 SXGKT 727
KT
Sbjct: 173 GKQKT 177
>UniRef50_Q8PMV7 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=7;
Xanthomonadaceae|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Xanthomonas axonopodis pv. citri
Length = 693
Score = 77.0 bits (181), Expect = 5e-13
Identities = 53/180 (29%), Positives = 92/180 (51%)
Frame = +2
Query: 185 IKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNP 364
I++V VIG G+MG IA +A G +VTL D + ++ I T L+R + K
Sbjct: 317 IRHVHVIGVGVMGGDIAAWAAYKGFDVTLQD-------REQRFIDTALTRGGELFAKRVK 369
Query: 365 QEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFAS 544
+ ++ R+ A ++ ADLV+EAI+EN K L++ ++ + +
Sbjct: 370 DDAKRPA--VAARLRGDLAGAGVTQ-ADLVIEAIIENPQAKRDLYQSIEPQLKPDALLTT 426
Query: 545 NTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXGK 724
NTSS+ + ++ ++R +F GLH+FNPV +M L+ +V+ A + + K+ K
Sbjct: 427 NTSSIPLTDLRGHIQRPAQFAGLHYFNPVAMMPLVEIVQHDGLDPANVARLAAFCKTLDK 486
>UniRef50_A0GEI2 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=2; Burkholderia|Rep: 3-hydroxyacyl-CoA
dehydrogenase, NAD-binding - Burkholderia phytofirmans
PsJN
Length = 317
Score = 77.0 bits (181), Expect = 5e-13
Identities = 56/168 (33%), Positives = 86/168 (51%), Gaps = 1/168 (0%)
Frame = +2
Query: 194 VTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNPQEV 373
+ V+G GLMG GIA SA G + DV LA S+ V ++ D +
Sbjct: 19 IGVVGTGLMGVGIATQSALHGHRTIVHDVDPARLA----SVAPKAQAVLDELI-DAGRID 73
Query: 374 EKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFASNTS 553
+L RI T + + SA V+EAI E + +KH+L+ L + I ASNTS
Sbjct: 74 PAAKQAALARIETHAEL-DVMASAQFVIEAIPEVLELKHRLYAALTQLLADDAILASNTS 132
Query: 554 SLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETS-EATYKT 694
+++A+ ++ KD+F HF+NP ++ L+ VV G+ T+ E T +T
Sbjct: 133 GFHPDQLAAPLRAKDRFVIAHFWNPPHMIPLVEVVPGTATAPEVTQQT 180
>UniRef50_Q0FMY4 Cluster: Enoyl-CoA hydratase; n=1; Roseovarius sp.
HTCC2601|Rep: Enoyl-CoA hydratase - Roseovarius sp.
HTCC2601
Length = 634
Score = 76.6 bits (180), Expect = 6e-13
Identities = 50/172 (29%), Positives = 82/172 (47%)
Frame = +2
Query: 185 IKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNP 364
I V+G G+GIA A+AG V L+D + +A+ I + D P
Sbjct: 291 ITRAAVVGADSAGAGIAMCFARAGLPVVLIDTDAAQIERARARIAELWDQARDGGGIDGP 350
Query: 365 QEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFAS 544
V + R+ +T+ A+ SAD+VV A+ E++ ++F LD + I +
Sbjct: 351 TLVAQ-----RARLELSTEL-HAAASADVVVAAVSEDMTQTQEIFSALDRICKPGAILVN 404
Query: 545 NTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMM 700
N ++L ++ IA +R G+HF P +RLL VV+G+ T+ T+M
Sbjct: 405 NGATLDLDSIAQATRRPGDVIGMHFLQPDGAVRLLEVVRGARTAPEVIATVM 456
>UniRef50_A1IFR8 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Candidatus Desulfococcus oleovorans Hxd3|Rep:
3-hydroxybutyryl-CoA dehydrogenase - Candidatus
Desulfococcus oleovorans Hxd3
Length = 304
Score = 76.6 bits (180), Expect = 6e-13
Identities = 47/183 (25%), Positives = 89/183 (48%)
Frame = +2
Query: 185 IKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNP 364
IK V ++G G MG I + A G + D+S L AKK + R + ++
Sbjct: 9 IKKVLILGAGSMGQQIGFLCAAKGFETAIYDLSPPLLDTAKKRLEKLAGRFVSR-HRLTG 67
Query: 365 QEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFAS 544
+E ++ R+ D+ +A+ +AD + E++ E++ +K ++F+ + P+ IF +
Sbjct: 68 EEAAA----AMARVTLTPDSEQAAANADFISESVTESVEIKCRVFETFHPLCPARAIFTT 123
Query: 545 NTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXGK 724
NTSSL + + V R D+F HF N + ++ ++ T+ T +T+ + G+
Sbjct: 124 NTSSLIPSMLTHAVGRPDRFAAFHFHNTL-TSDIVDIMPHPGTTPETAETIRAFALRLGQ 182
Query: 725 TCI 733
I
Sbjct: 183 VPI 185
>UniRef50_Q9UX37 Cluster: 3-hydroxyacyl-CoA-dehydrogenase; n=4;
Sulfolobaceae|Rep: 3-hydroxyacyl-CoA-dehydrogenase -
Sulfolobus solfataricus
Length = 324
Score = 76.6 bits (180), Expect = 6e-13
Identities = 55/176 (31%), Positives = 85/176 (48%), Gaps = 1/176 (0%)
Frame = +2
Query: 182 AIKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDN 361
+I V VIG G++G G + G V L + L KA + L + K + N
Sbjct: 7 SINKVAVIGAGVIGVGWTTLLLAKGYKVNLYTEKKETLEKALAKVSAYLVNL-KNLGMIN 65
Query: 362 PQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFA 541
+E E ++ + G T +A + D V+EAI+E+ K LFK LD P I A
Sbjct: 66 -EEPESYITNLTG----ITKIDDAIHNVDFVIEAIIEDYTAKKNLFKLLDTQLPQDIIIA 120
Query: 542 SNTSSLSINEIASVVKRKDKFGGL-HFFNPVPVMRLLXVVKGSETSEATYKTMMEW 706
S+TS L + EI + R + G + H +NP ++ L+ +V G +TS+ T E+
Sbjct: 121 SSTSGLLMTEIQKAMIRHPERGVIAHPWNPPHLLPLVEIVPGEKTSKETVDLTREF 176
>UniRef50_Q0YNJ7 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Geobacter sp. FRC-32|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Geobacter sp. FRC-32
Length = 311
Score = 76.2 bits (179), Expect = 8e-13
Identities = 51/165 (30%), Positives = 80/165 (48%), Gaps = 3/165 (1%)
Frame = +2
Query: 200 VIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNPQEVEK 379
++G G+MG G A +G V D S LA + AKK D+P
Sbjct: 5 ILGTGIMGRGWITQCAMSGHEVHCHDASPQTLAGTVAGCEKLAATAAKKFKHDDPN---- 60
Query: 380 FVNDSLGRINTATDAA---EASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFASNT 550
FV++++G+I + +A+K D+ +E I E++ +K + P +F SN+
Sbjct: 61 FVSNAMGKIRVHNEKGAFIDAAKGCDVFLEVIFEDLKLKCSVLADYLPQLPPSVVFWSNS 120
Query: 551 SSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEAT 685
SSL I+ +A R D+ H NPVP+M + VV G++TS T
Sbjct: 121 SSLDIDPMAQAGGRPDRSIVTHGMNPVPLMPGVEVVPGAKTSSET 165
>UniRef50_Q0AI36 Cluster: 3-hydroxybutyryl-CoA epimerase; n=3;
Nitrosomonadaceae|Rep: 3-hydroxybutyryl-CoA epimerase -
Nitrosomonas eutropha (strain C71)
Length = 852
Score = 75.4 bits (177), Expect = 1e-12
Identities = 49/169 (28%), Positives = 86/169 (50%), Gaps = 4/169 (2%)
Frame = +2
Query: 185 IKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNP 364
++ V+G G+MG+ IA A L ++S ++ + N+ + ++ K +P
Sbjct: 20 VRKAAVLGAGVMGAQIAAHLVNANIETLLFELSAES-----GNPDANVLKAINRLNKQDP 74
Query: 365 QEVEKFVNDSLGRINTATDAAEASK--SADLVVEAIVENIGVKHKLFKQLDGVAPSHTIF 538
+ V D I A K DLV+EAI E + +K +L++++ + I
Sbjct: 75 SPLS--VIDRASCIEPANYEQHLEKLGECDLVIEAITERLELKSELYEKVAPYLNNQAIL 132
Query: 539 ASNTSSLSINEIASVVKR--KDKFGGLHFFNPVPVMRLLXVVKGSETSE 679
ASNTS LSIN++A+ V + +F G+HFFNP M L+ ++ G ++ +
Sbjct: 133 ASNTSGLSINQLAAAVPEALRPRFCGIHFFNPPRYMYLVELIPGKQSDQ 181
>UniRef50_A3ZZK1 Cluster: 3-hydroxybutyryl-coA dehydrogenase; n=1;
Blastopirellula marina DSM 3645|Rep:
3-hydroxybutyryl-coA dehydrogenase - Blastopirellula
marina DSM 3645
Length = 319
Score = 74.9 bits (176), Expect = 2e-12
Identities = 47/180 (26%), Positives = 84/180 (46%)
Frame = +2
Query: 185 IKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNP 364
I+ V V+G GLMG GI V D++ ++ A A+ + + L +A+ +P
Sbjct: 3 IRTVGVVGLGLMGRGICTSLLANNFQVVAYDINPESFAAARAHVASALEELAR-----HP 57
Query: 365 QEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFAS 544
E + D + D V+E+I E+ +K + L+ + P+ T AS
Sbjct: 58 SVAEAIPENWPSHFQLTADLSPLG-DCDFVIESIPEDPVIKQETIAALERLLPNSTPIAS 116
Query: 545 NTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXGK 724
NTS+L I+ + + + + G+H+ P + R L +++G T +AT + G+ GK
Sbjct: 117 NTSALPISLLQAHCQLPQRIIGMHWAEPCHLTRFLEIIRGEHTDDATADSAANLGRQLGK 176
>UniRef50_Q4J0Z7 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
C-terminal:3-hydroxyacyl-CoA dehydrogenase, NAD binding
domain; n=2; Gammaproteobacteria|Rep: 3-hydroxyacyl-CoA
dehydrogenase, C-terminal:3-hydroxyacyl-CoA
dehydrogenase, NAD binding domain - Azotobacter
vinelandii AvOP
Length = 307
Score = 74.5 bits (175), Expect = 2e-12
Identities = 48/160 (30%), Positives = 86/160 (53%)
Frame = +2
Query: 194 VTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNPQEV 373
+ ++G GLMG GIA A+ G V L D + + LA+ G+ L+ +A + Q
Sbjct: 6 IVILGAGLMGIGIATHLARHGHAVLLRDPAAERLAEVPVMAGSILAELADAGRFERAQ-- 63
Query: 374 EKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFASNTS 553
+ +L R+ + A+ + A L++EAI E + +K L+ +L+ + + T+ ASNTS
Sbjct: 64 ---TDATLARLAVSPRLADVA-DARLLIEAIPERLELKRALYAELEALVGTGTVIASNTS 119
Query: 554 SLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSET 673
L + +A ++ ++ HF+NP ++ L+ +V GS T
Sbjct: 120 GLPPDALAEGMRHPERLLIAHFWNPPHLIPLVEIVPGSAT 159
>UniRef50_Q2SGN8 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Hahella chejuensis KCTC 2396|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Hahella chejuensis (strain KCTC 2396)
Length = 283
Score = 73.7 bits (173), Expect = 4e-12
Identities = 53/181 (29%), Positives = 83/181 (45%)
Frame = +2
Query: 191 NVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNPQE 370
N+ VIGGG +GS +A A G NV +V+ + +++ + A +P
Sbjct: 5 NIAVIGGGNIGSSLAFDCALRGHNVVVVEKDEPSCEQSRARV----LETAGYAPLFSPLA 60
Query: 371 VEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFASNT 550
K D L I + + S A VVE I ENI +K L+ ++ + + A+NT
Sbjct: 61 KGKKPQDILDNIRWSNELGAISDCA-FVVENIPENIELKQALYTRMAEFIAPNAVLAANT 119
Query: 551 SSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXGKTC 730
S + I ++ S K + G+HF NPV + + V+ G TSE T +E GK
Sbjct: 120 SCIPITKLGSFHKTSAQVIGVHFMNPVYLKHTVEVILGLNTSEQTKDRCLEMLAMLGKKA 179
Query: 731 I 733
+
Sbjct: 180 V 180
>UniRef50_A5UXI1 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor; n=6; Bacteria|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding precursor -
Roseiflexus sp. RS-1
Length = 807
Score = 73.7 bits (173), Expect = 4e-12
Identities = 62/200 (31%), Positives = 89/200 (44%), Gaps = 15/200 (7%)
Frame = +2
Query: 185 IKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNL-SRVAKKMYK-- 355
IK V VIG G MG GIA AG V L+D +L ++ G L S+ + +
Sbjct: 4 IKKVAVIGAGTMGGGIAAHCINAGLQVVLLDTVPSSLTPEEEKRGLTLESKEVRNRFVRA 63
Query: 356 -----DNPQEVEKFVNDSLGRINTAT--DAAEASKSADLVVEAIVENIGVKHKLFKQLDG 514
N + F S+ RI T D AD +VEAI+E + K L ++++
Sbjct: 64 GLERIKNARPAALFDPQSISRIVTGNVEDDLALIADADWIVEAIIEQLEPKRALMEKIEQ 123
Query: 515 VAPSHTIFASNTSSLSINEIASVVKRKDKFG----GLHFFNPVPVMRLLXVVKGSETSEA 682
V +I +SNTS + I IA+ R D F G HFFNP + LL V+ +T
Sbjct: 124 VRKPGSIVSSNTSGIPIAAIAA--GRSDDFRRHFLGTHFFNPPRYLYLLEVIPTPDTDPQ 181
Query: 683 TYKTMMEWGK-SXGKTCITC 739
+ + + GK + C
Sbjct: 182 VVAAISRFADVTLGKGVVIC 201
>UniRef50_Q586V7 Cluster: Enoyl-CoA hydratase/Enoyl-CoA
isomerase/3-hydroxyacyl-CoA dehydrogenase, putative;
n=3; Trypanosoma|Rep: Enoyl-CoA hydratase/Enoyl-CoA
isomerase/3-hydroxyacyl-CoA dehydrogenase, putative -
Trypanosoma brucei
Length = 803
Score = 73.7 bits (173), Expect = 4e-12
Identities = 49/192 (25%), Positives = 89/192 (46%)
Frame = +2
Query: 158 SNSSAMQSAIKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRV 337
+ + Q ++ + V+G G++G GI ++ +AG V L+ ++ A I + L
Sbjct: 341 AGTGLQQQRLRKLAVVGCGVVGIGIVIMALRAGSQVVLLGEDDNECEYALHVIKSELPND 400
Query: 338 AKKMYKDNPQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGV 517
A Y + V ++N+ L + D + D++ E IV ++ K ++F L +
Sbjct: 401 ALG-YNISADCVNMYLNN-LKVLPYHGDLQTVLQDVDVMAECIVGDLDTKRQVFTMLTDL 458
Query: 518 APSHTIFASNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTM 697
P H + A+ SSL + E V +R +K G++F PV + L V +G T T +
Sbjct: 459 CPPHCVLATCCSSLELREFVKVSRRPEKVVGMYFAPPVHNVPFLEVTRGYRTDHTTLQRA 518
Query: 698 MEWGKSXGKTCI 733
+ G+ K I
Sbjct: 519 IHVGRLFHKATI 530
>UniRef50_Q8KUG1 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=8;
Actinomycetales|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Actinosynnema pretiosum subsp. auranticum
Length = 341
Score = 72.5 bits (170), Expect = 1e-11
Identities = 51/163 (31%), Positives = 75/163 (46%)
Frame = +2
Query: 200 VIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNPQEVEK 379
V+G G+MG GI ++ G V LVD D L A+ + +L R A+ +
Sbjct: 62 VLGAGVMGCGITALALSRGLPVLLVDPDADRLDAARADVRAHL-RTAQLL---------G 111
Query: 380 FVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFASNTSSL 559
LG + TATD + VVEA+ E+ K K + P T SNTSS+
Sbjct: 112 VAAGPLGELTTATDTG-GPREVVAVVEAVTEDAETKAKALTGVCATVPPGTPLVSNTSSI 170
Query: 560 SINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATY 688
+ E+A + R G HF NP ++ + V +G TS+A +
Sbjct: 171 PMGELAPALPRPGDLVGAHFMNPPYLIPAVEVARGPLTSDAAF 213
>UniRef50_A1B712 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor; n=2; Alphaproteobacteria|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding precursor -
Paracoccus denitrificans (strain Pd 1222)
Length = 765
Score = 72.5 bits (170), Expect = 1e-11
Identities = 60/195 (30%), Positives = 94/195 (48%), Gaps = 6/195 (3%)
Frame = +2
Query: 173 MQSAIKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMY 352
M +AI+ V V+G G+MG+GIA A AG V L+DV KA G +R
Sbjct: 1 MITAIEKVAVLGAGVMGAGIAAHLANAGVRVVLLDVD-----KAAADAGIRRAR------ 49
Query: 353 KDNPQEVEKFVNDSLG-RINTATDAAEAS--KSADLVVEAIVENIGVKHKLFKQLDGVAP 523
+ F++ + RI T + + S AD +VEA+ E + +K L++QL G+
Sbjct: 50 -----DEGGFMDPAFAARIATGSTVRDLSLLADADWIVEALPERLALKQSLYRQLQGIRK 104
Query: 524 SHTIFASNTSSLSINEIASVVKR--KDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTM 697
+I +SNTS++ + + + F HFFNP MRLL +V G T +
Sbjct: 105 PGSILSSNTSTIPLAALVGGMAGDFAADFLITHFFNPPRRMRLLELVAGPATRPEIVALI 164
Query: 698 MEW-GKSXGKTCITC 739
++ + GK ++C
Sbjct: 165 TDFCDRRLGKDVVSC 179
>UniRef50_Q6SEY0 Cluster: 3-hydroxyacyl-CoA dehydrogenase domain
protein; n=1; uncultured bacterium 582|Rep:
3-hydroxyacyl-CoA dehydrogenase domain protein -
uncultured bacterium 582
Length = 322
Score = 72.1 bits (169), Expect = 1e-11
Identities = 51/182 (28%), Positives = 88/182 (48%)
Frame = +2
Query: 191 NVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNPQE 370
+V+V+G GL+G G A V A+AG VTL D+ L A K + L + + +P
Sbjct: 16 SVSVVGAGLIGCGWAIVFARAGWQVTLQDIDLAKLQGAPKVLAVQLRMLEQHDLCADPAG 75
Query: 371 VEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFASNT 550
+ L RI+ +D A D V E E +G+K +LF +LD + P TI AS+T
Sbjct: 76 I-------LARISYESDLKTAVCEVDYVQECGPEVLGLKQELFSELDALTPPETILASST 128
Query: 551 SSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXGKTC 730
S L ++ ++ + + + H NP ++ ++ + T + +++ G+T
Sbjct: 129 SGLMASQFSAHLAGRHRALVAHPVNPPHLVPVVEISPSEWTDPEIVRVVVDVMTGVGQTP 188
Query: 731 IT 736
+T
Sbjct: 189 VT 190
>UniRef50_Q0RL76 Cluster: Putative 3-hydroxybutyryl-CoA
dehydrogenase; n=1; Frankia alni ACN14a|Rep: Putative
3-hydroxybutyryl-CoA dehydrogenase - Frankia alni
(strain ACN14a)
Length = 234
Score = 72.1 bits (169), Expect = 1e-11
Identities = 48/172 (27%), Positives = 87/172 (50%), Gaps = 2/172 (1%)
Frame = +2
Query: 215 LMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSI--GTNLSRVAKKMYKDNPQEVEKFVN 388
+MG+GIAQ A AG V VD S A +A++ + G R A + K +V++
Sbjct: 1 MMGTGIAQAVAVAGGAVVCVDTSAAARERARRQLVEGRFGLRAAVERGKLAAADVDRVA- 59
Query: 389 DSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFASNTSSLSIN 568
RI+ ++ + + +A +V+EA+ E++ +K ++F++LD VA + + A+N+S +
Sbjct: 60 ---ARISWESELSAVAGAA-VVIEAVPEDLALKVRVFRELDRVAAAGAVLATNSSGFPVG 115
Query: 569 EIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXGK 724
+A+ R + G H+ +P +MR +V T T+ GK
Sbjct: 116 ALAAATDRPTRVLGWHWSSPAQIMRFAEIVVTEHTDPDAVATVTRLAHGLGK 167
>UniRef50_Q11EZ3 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor; n=3; Bacteria|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding precursor -
Mesorhizobium sp. (strain BNC1)
Length = 318
Score = 71.7 bits (168), Expect = 2e-11
Identities = 48/164 (29%), Positives = 83/164 (50%)
Frame = +2
Query: 191 NVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNPQE 370
+++++G G +G A + A G +V + D DA +A + + L +AK P +
Sbjct: 12 SISIVGAGSIGVAFAVLFASRGASVRIWDALPDAFDRAANELRSRLEMLAKASALSEPPD 71
Query: 371 VEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFASNT 550
+ RI+ + AEA ADLV E ENI +K LF+ L + P H + AS++
Sbjct: 72 ------EISSRISWHRNLAEALDGADLVQECAPENIDLKVDLFRWLADLTPDHVVLASSS 125
Query: 551 SSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEA 682
S+L + IA ++ + + H NP ++ ++ VV ET++A
Sbjct: 126 SALIASLIAPDIEIRRRVLVGHPGNPPYLIPVIEVVPSPETAQA 169
>UniRef50_Q4Q3S6 Cluster: Enoyl-CoA hydratase/Enoyl-CoA
isomerase/3-hydroxyacyl-CoA dehydrogenase, putative;
n=5; Leishmania|Rep: Enoyl-CoA hydratase/Enoyl-CoA
isomerase/3-hydroxyacyl-CoA dehydrogenase, putative -
Leishmania major
Length = 934
Score = 71.7 bits (168), Expect = 2e-11
Identities = 55/187 (29%), Positives = 85/187 (45%), Gaps = 6/187 (3%)
Frame = +2
Query: 158 SNSSAMQSAIKNVTVIGGGLMGSGIA-QVSAQAGQNVTLVDVSNDALAKAKKSIGTNL-S 331
++ + Q +K V VIG G MG+ IA + Q+ V LV+ A++SI L S
Sbjct: 404 TDDATAQLGLKKVAVIGAGTMGTSIALMLLRQSEIEVVLVEADTQRQEVARRSIEDYLRS 463
Query: 332 RVAKKMYKDNPQEVEKFVNDSLGRINTATDAAE----ASKSADLVVEAIVENIGVKHKLF 499
RV ++ ND L R+ ADLV E E +K +
Sbjct: 464 RVEAHRLS------QRRCNDMLHRLRVMGSRIAPFPPVLADADLVFECAPEVAAIKQNIL 517
Query: 500 KQLDGVAPSHTIFASNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSE 679
LD V TI A+ +S+ +NE+A+V +R + G+HFF P L+ V++G+ T
Sbjct: 518 AFLDSVCKRSTILATGSSAQDVNELAAVTQRPGQVLGIHFFPPANESPLVEVIRGAATER 577
Query: 680 ATYKTMM 700
+ +M
Sbjct: 578 WVVELVM 584
>UniRef50_Q396V2 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=9;
Bacteria|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Burkholderia sp. (strain 383) (Burkholderia cepacia
(strain ATCC 17760/ NCIB 9086 / R18194))
Length = 317
Score = 71.3 bits (167), Expect = 2e-11
Identities = 57/188 (30%), Positives = 90/188 (47%), Gaps = 1/188 (0%)
Frame = +2
Query: 173 MQSAIKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMY 352
M + IK V VIG G++G+ A + G +V DV+ DA A+ ++ + +
Sbjct: 1 MATPIKRVAVIGTGVIGASWAALFLAKGLDVAATDVAPDAEARLRQYLDAAWPAL----- 55
Query: 353 KDNPQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHT 532
+E+ S R+ D AEA A LV E E I K L+ QLD + P
Sbjct: 56 ----EELGLAPAASRARLTFTHDLAEAVAGAGLVQENGPERIDFKRTLYGQLDALLPPDV 111
Query: 533 IFASNTSSLSINEI-ASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWG 709
AS++S L+++EI ++ H FNP ++ L+ +V G++TSE T + + +
Sbjct: 112 PIASSSSGLTMSEIQTGCPAHPERCVIGHPFNPPHLIPLVEIVSGAQTSEQTVEKVTAFY 171
Query: 710 KSXGKTCI 733
S GK I
Sbjct: 172 TSLGKRTI 179
>UniRef50_A4SW27 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=7;
Burkholderiales|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Polynucleobacter sp. QLW-P1DMWA-1
Length = 313
Score = 70.9 bits (166), Expect = 3e-11
Identities = 49/161 (30%), Positives = 82/161 (50%)
Frame = +2
Query: 194 VTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNPQEV 373
V ++GGG MG+ +A V A+ G V +V+ + + A ++ + Y+ +
Sbjct: 10 VVIVGGGTMGADVAAVCARGGCAVQVVEPTTERRALLPDYFVNTMTDLG---YEHRIHLL 66
Query: 374 EKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFASNTS 553
V SL ++ A DLV+E + E + +K +LF +L+ A + ASN++
Sbjct: 67 T--VAGSLEEVDWA--------DVDLVIECVPERLDIKQELFAKLEKYAKPEAVLASNST 116
Query: 554 SLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETS 676
S I+EIAS +K + GLHFF P ++ + VV G +TS
Sbjct: 117 SFPISEIASGLKTAARMIGLHFFMPAHLVPCVEVVYGEKTS 157
>UniRef50_Q0FUM2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2;
Rhodobacterales|Rep: 3-hydroxybutyryl-CoA dehydrogenase
- Roseovarius sp. HTCC2601
Length = 220
Score = 70.5 bits (165), Expect = 4e-11
Identities = 43/160 (26%), Positives = 80/160 (50%)
Frame = +2
Query: 194 VTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNPQEV 373
+ V+G G MG IA + A G + + D SN + +A + +D+
Sbjct: 16 ICVVGAGFMGCVIATLYAHHGYDAVICD-SNQTMLDTYVE---RARPIAAGLVEDSDAS- 70
Query: 374 EKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFASNTS 553
L + D A A + LV EA+ E++ VK LF +L+ + P + + A+NTS
Sbjct: 71 ----EAMLAGVTLEPDLASAIEGVFLVHEAVQESLEVKQALFAELERICPENVVLATNTS 126
Query: 554 SLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSET 673
S I++IA+ + RK++ G+H+ P ++ ++ ++ ++T
Sbjct: 127 SFLISDIAAQMTRKERMMGIHYVTPGHIVPVIELIHAADT 166
>UniRef50_Q1INT0 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor; n=1; Acidobacteria bacterium
Ellin345|Rep: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor - Acidobacteria bacterium (strain
Ellin345)
Length = 806
Score = 70.1 bits (164), Expect = 5e-11
Identities = 54/185 (29%), Positives = 86/185 (46%), Gaps = 6/185 (3%)
Frame = +2
Query: 173 MQSAIKNVTVIGGGLMGSGIAQVSAQAGQNVTLVD-VSNDALAKAKKSIGTNLSRVAKKM 349
M I+ V V+G G MG+ IA A AG L D V DA A+ I AKK
Sbjct: 1 MLKRIEKVAVLGAGTMGARIAAHFANAGIPSYLFDIVPPDADGPARNKIAAAGLDAAKK- 59
Query: 350 YKDNPQEVEKFVNDSLGRINTATDAAEASKS---ADLVVEAIVENIGVKHKLFKQLDGVA 520
+ F + L ++ T + + K D ++EA+VEN+ +K L K+++ V
Sbjct: 60 -----SKPAAFFHPDLAKLVTVGNFEDDLKKLGECDWIIEAVVENLELKRALLKKVEAVR 114
Query: 521 PSHTIFASNTSSLSINEIASVVKR--KDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKT 694
++ +NTS L +++I+ + + G HFFNP MRLL ++ +T +
Sbjct: 115 KPGSLITTNTSGLPVSKISEGFSEDFRRNWFGTHFFNPPRYMRLLELIPTPDTDPKAMEA 174
Query: 695 MMEWG 709
+ G
Sbjct: 175 VAHLG 179
>UniRef50_Q89HA7 Cluster: Blr6087 protein; n=6; Proteobacteria|Rep:
Blr6087 protein - Bradyrhizobium japonicum
Length = 330
Score = 69.7 bits (163), Expect = 7e-11
Identities = 48/187 (25%), Positives = 84/187 (44%), Gaps = 4/187 (2%)
Frame = +2
Query: 191 NVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNPQE 370
N+ +G G MG GIA A AG VT++DV + K L V K +
Sbjct: 6 NIACLGAGRMGRGIAVAFAYAGHRVTMIDVKPRSAEDFAKLETDALGEVRKTFASLSNLG 65
Query: 371 V--EKFVNDSLGRINTATDAAEASKSAD--LVVEAIVENIGVKHKLFKQLDGVAPSHTIF 538
+ E V+ + R++ AT + + AD +V E + E + +K ++ TI
Sbjct: 66 LLTEADVDPLVARVSVATASQSGTALADAGMVFEGVPEVVELKREVLGAASRQVKPDTII 125
Query: 539 ASNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSX 718
AS TS++ +++++ + +F +H+ NP ++ L+ V G T A + +
Sbjct: 126 ASTTSTILVDDLSGAIVNPHRFLNVHWLNPAYLIPLVEVSPGKATDPAIIDEVKALLEGI 185
Query: 719 GKTCITC 739
GK + C
Sbjct: 186 GKVPVVC 192
>UniRef50_Q39D25 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=48;
Burkholderiales|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Burkholderia sp. (strain 383) (Burkholderia cepacia
(strain ATCC 17760/ NCIB 9086 / R18194))
Length = 849
Score = 69.7 bits (163), Expect = 7e-11
Identities = 54/165 (32%), Positives = 83/165 (50%), Gaps = 2/165 (1%)
Frame = +2
Query: 185 IKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNP 364
I+ V V+G G+MG+ IA A V L D+ A K +I KK+ P
Sbjct: 44 IRKVAVLGAGVMGAQIAAHLINARVPVLLFDLP--AKEGPKNAIALKAIESLKKL-SPAP 100
Query: 365 QEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFAS 544
V+ L N D A+ ++ D+V+EAI E + KH L+K++ + IFA+
Sbjct: 101 FGVKDDAK-YLEAANYEDDIAKLAE-CDVVIEAIAERMDWKHDLYKKVAPHIAPNAIFAT 158
Query: 545 NTSSLSINEIASVV--KRKDKFGGLHFFNPVPVMRLLXVVKGSET 673
NTS LSI +++ + K +F G+HFFNP M L+ ++ + T
Sbjct: 159 NTSGLSITKLSEGFSDELKSRFCGVHFFNPPRYMHLVELIPTAHT 203
>UniRef50_A7HED1 Cluster: 3-hydroxyacyl-CoA dehydrogenase
NAD-binding; n=4; Deltaproteobacteria|Rep:
3-hydroxyacyl-CoA dehydrogenase NAD-binding -
Anaeromyxobacter sp. Fw109-5
Length = 795
Score = 68.9 bits (161), Expect = 1e-10
Identities = 53/185 (28%), Positives = 86/185 (46%), Gaps = 12/185 (6%)
Frame = +2
Query: 185 IKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLS------RVAK- 343
I V V+G G+MGS IA A AG V L+DV ++ +++ G L R+A
Sbjct: 4 IDRVAVLGAGVMGSTIAAHLANAGFRVLLLDVVPKEPSEEERAAGLGLGDRAVRDRIAAA 63
Query: 344 -KMYKDNPQEVEKFVNDSLGRINTAT--DAAEASKSADLVVEAIVENIGVKHKLFKQLDG 514
+ + + ++ + GRI D + D V+E +VE++ VK +L ++
Sbjct: 64 GRAGLERLKPAPLYLPEHAGRIEVGNLEDDLPRLRDRDWVIEVVVEDLAVKQQLLGRVAA 123
Query: 515 VAPSHTIFASNTSSLSINEIASVVKR--KDKFGGLHFFNPVPVMRLLXVVKGSETSEATY 688
+ ++NTS LS+N +A + + + HFFNP MRL+ +V T A
Sbjct: 124 HLRPDAVLSTNTSGLSVNALAESLPEPLRPRLLVTHFFNPPRYMRLVELVSSRFTDRAVA 183
Query: 689 KTMME 703
M E
Sbjct: 184 ARMAE 188
>UniRef50_Q392L7 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=9;
Bacteria|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Burkholderia sp. (strain 383) (Burkholderia cepacia
(strain ATCC 17760/ NCIB 9086 / R18194))
Length = 336
Score = 67.7 bits (158), Expect = 3e-10
Identities = 53/190 (27%), Positives = 90/190 (47%), Gaps = 5/190 (2%)
Frame = +2
Query: 185 IKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSN-DALAKAKKSIGTNLSRVAKKMYKDN 361
+ + V+G G MG GIA V A AG +VTL+D DA+ ++ T +A+ ++
Sbjct: 7 VTRIHVLGAGRMGQGIALVFAFAGIDVTLIDFKRRDAVGQSAFDDRTR-DEIARPLHAQV 65
Query: 362 PQ-EVEKFVNDSL-GRIN-TATD-AAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSH 529
++ D++ RI A D AAEA + AD+V EA+ E + K + L +
Sbjct: 66 ALGRIDAAQADAVVARIAIVARDGAAEAVRDADIVFEALPEVLDAKADALRWLGEHVDAR 125
Query: 530 TIFASNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWG 709
AS TS+ + E+ V R ++ H+ NP +M L+ + + T ++ +
Sbjct: 126 ATIASTTSTFVVTELQRHVVRPERMLNAHWLNPALLMPLVEISRSDATDQSVVDALAALL 185
Query: 710 KSXGKTCITC 739
+ GK + C
Sbjct: 186 ERVGKKPVIC 195
>UniRef50_Q160J3 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenase;
n=1; Roseobacter denitrificans OCh 114|Rep: Putative
3-hydroxyacyl-CoA dehydrogenase - Roseobacter
denitrificans (strain ATCC 33942 / OCh 114)
(Erythrobactersp. (strain OCh 114)) (Roseobacter
denitrificans)
Length = 331
Score = 67.7 bits (158), Expect = 3e-10
Identities = 45/182 (24%), Positives = 93/182 (51%)
Frame = +2
Query: 188 KNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNPQ 367
++V +IG GL+G A V +AG VTL D ++ + +AK + ++ A+ + +
Sbjct: 17 RSVAIIGCGLIGQAWATVFLRAGMRVTLYDAASGLVEQAKAQVIERMTEFARFDLVTH-E 75
Query: 368 EVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFASN 547
+E+ + I A +A +AD + E+ E + VK +L +++D A H + S+
Sbjct: 76 TLER----APAHIELADTLEDAVSAADYIQESGSEALDVKIELTREIDRFAAPHVVIGSS 131
Query: 548 TSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXGKT 727
TS ++ + + +K +++ +H NP ++ L+ VV T+++ T+ + + G+
Sbjct: 132 TSGITASRYSETIKGRERCLVVHPINPPHLVPLVEVVPAPWTAQSAVDTVHDLLSAIGQV 191
Query: 728 CI 733
I
Sbjct: 192 PI 193
>UniRef50_A5V325 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=1; Sphingomonas wittichii RW1|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Sphingomonas wittichii RW1
Length = 322
Score = 67.7 bits (158), Expect = 3e-10
Identities = 51/181 (28%), Positives = 85/181 (46%)
Frame = +2
Query: 182 AIKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDN 361
AI V IGGG++G G +G+ V L D + A A+ + + ++A
Sbjct: 9 AIGTVAAIGGGVIGGGWVAAFLGSGRAVRLHDPAPGAEARIRAHVTQAWPQMAAL----- 63
Query: 362 PQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFA 541
+ + +D GR++ +A + D V E E VK LF +LD + P+ +
Sbjct: 64 --GLARADDDWTGRLSFHETIEDAVEGTDFVQENTPERSDVKRALFAELDRLVPADVLVG 121
Query: 542 SNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXG 721
S+TSSL I+++ + + +F H FNPV ++ L+ V G T A T + + + G
Sbjct: 122 SSTSSLPISDLQAGLSTAARFVLGHPFNPVHLIPLVEVGGGDATDPAAVDTALAFYAALG 181
Query: 722 K 724
K
Sbjct: 182 K 182
>UniRef50_O28262 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=2;
Archaeoglobus fulgidus|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Archaeoglobus fulgidus
Length = 281
Score = 67.7 bits (158), Expect = 3e-10
Identities = 54/182 (29%), Positives = 90/182 (49%)
Frame = +2
Query: 194 VTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNPQEV 373
V VIG GLMG GIA ++ + V L DVS AL A++ I P+E+
Sbjct: 3 VFVIGAGLMGRGIA-IAIASKHEVVLQDVSEKALEAAREQI---------------PEEL 46
Query: 374 EKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFASNTS 553
L +I T E K D+V+EA+ E++ K ++ ++++ + ++ SNTS
Sbjct: 47 -------LSKIEFTT-TLEKVKDCDIVMEAVFEDLNTKVEVLREVERL--TNAPLCSNTS 96
Query: 554 SLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXGKTCI 733
+S+++IA + +F G+H+ NP VM L+ +V T T + + + GK +
Sbjct: 97 VISVDDIAERLDSPSRFLGVHWMNPPHVMPLVEIVISRFTDSKTVAFVEGFLRELGKEVV 156
Query: 734 TC 739
C
Sbjct: 157 VC 158
>UniRef50_Q7WLK3 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenase;
n=3; Bordetella|Rep: Putative 3-hydroxyacyl-CoA
dehydrogenase - Bordetella bronchiseptica (Alcaligenes
bronchisepticus)
Length = 313
Score = 67.3 bits (157), Expect = 4e-10
Identities = 46/135 (34%), Positives = 69/135 (51%), Gaps = 1/135 (0%)
Frame = +2
Query: 185 IKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNP 364
+ +V VIGGG++G+ A V A+ G VT+V+ LA + + R A +
Sbjct: 1 MNHVAVIGGGIIGASWAVVFARRGLEVTIVERDAACLAGLPARLAGMIERSASLLGAGEQ 60
Query: 365 QEVEKFVNDSLGRINTATDA-AEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFA 541
D RI ATDA A A AD V EA+ EN+ +K LF +LD +AP+H + A
Sbjct: 61 P------GDVAARIG-ATDALAAAVGRADYVQEAVSENLALKRTLFAELDALAPAHALLA 113
Query: 542 SNTSSLSINEIASVV 586
S+TS+ ++ +
Sbjct: 114 SSTSTYGASQFTEAL 128
>UniRef50_A5ULU2 Cluster: 3-hydroxyacyl-CoA dehydrogenase, FadB;
n=3; cellular organisms|Rep: 3-hydroxyacyl-CoA
dehydrogenase, FadB - Methanobrevibacter smithii (strain
PS / ATCC 35061 / DSM 861)
Length = 318
Score = 67.3 bits (157), Expect = 4e-10
Identities = 53/197 (26%), Positives = 91/197 (46%), Gaps = 20/197 (10%)
Frame = +2
Query: 185 IKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAK------KSIGTNLSRVAK- 343
+K + V GGG++GS IA SA G +VT+ S ++ +A+ K I N K
Sbjct: 10 MKKIVVAGGGVLGSQIALQSAFCGFDVTIWLRSEGSIERAQPKLLRLKEIYLNTLEAMKT 69
Query: 344 -------------KMYKDNPQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGV 484
++ D E+++ V D+ I T EA ADL++EAI E+
Sbjct: 70 NPAAYCRGFSCENELSADKINELKQKVEDAYDSITLTTSYEEAGNDADLIIEAIAEDPKQ 129
Query: 485 KHKLFKQLDGVAPSHTIFASNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKG 664
K +++L P TI A+N+S++ + A R +K+ LHF N + ++
Sbjct: 130 KIAFYQELAKHIPEKTIIATNSSTMLPSAFAQYTGRPEKYLALHFANEIWRNNTAEIMGH 189
Query: 665 SETSEATYKTMMEWGKS 715
+T + Y + E+ ++
Sbjct: 190 PDTGQEYYDAVCEFAEN 206
>UniRef50_A2QA05 Cluster: Catalytic activity:; n=4;
Trichocomaceae|Rep: Catalytic activity: - Aspergillus
niger
Length = 622
Score = 66.5 bits (155), Expect = 6e-10
Identities = 51/172 (29%), Positives = 83/172 (48%), Gaps = 2/172 (1%)
Frame = +2
Query: 179 SAIKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKD 358
S + + +IG G++G IA V + AG +V + D S AL A+ I T++ + +
Sbjct: 12 SKSRPIVIIGAGILGRRIAAVFSSAGYSVHISDPSPSALDSARTYISTHIHEFTTHIPRP 71
Query: 359 NPQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIF 538
+ S G I+T T EA +A L+VEA+ E + +K LF L +P+ I
Sbjct: 72 SL---------SPGPISTFTSVPEAVATAWLIVEAVPEILPIKQSLFADLHAHSPADCIL 122
Query: 539 ASNTSSLSINEIAS--VVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATY 688
ASN+SS I + R+ +HF P P +R + ++ +T E +
Sbjct: 123 ASNSSSYKSRLIGGHLPLPRRVLLLNMHFTMP-PAIRTVELMTCGDTHERVF 173
>UniRef50_Q5P5K6 Cluster: Fusion of 3-hydroxyacyl-CoA dehydrogenase
and enoyl-CoA hydratase; n=20; Proteobacteria|Rep:
Fusion of 3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA
hydratase - Azoarcus sp. (strain EbN1) (Aromatoleum
aromaticum (strain EbN1))
Length = 797
Score = 66.1 bits (154), Expect = 8e-10
Identities = 55/178 (30%), Positives = 80/178 (44%), Gaps = 4/178 (2%)
Frame = +2
Query: 185 IKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNL-SRVAKKMYKDN 361
I+ V V+G G+MG+ IA A A V L D+ AK + R + K +
Sbjct: 6 IRKVAVLGAGVMGAQIAAHCANADVPVVLFDLP------AKDGPPNRVVDRAIGGLTKLD 59
Query: 362 PQEVEKFVNDS-LGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIF 538
P + V S + N +D E + DLV+EAI E + K L+ + IF
Sbjct: 60 PAPLAAAVRASHIDAANYDSDL-ERLRDCDLVIEAIAEKLEWKRDLYAKAAPYLRPDAIF 118
Query: 539 ASNTSSLSINEIASVVKR--KDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEW 706
ASNTS LSI +A + + +F G+HFFNP M L+ ++ T + W
Sbjct: 119 ASNTSGLSIATLAEGLPEALRSRFCGVHFFNPPRYMALVELIPAPATDPLMLDALEAW 176
>UniRef50_Q0SA65 Cluster: Possible 3-hydroxybutyryl-CoA
dehydrogenase; n=1; Rhodococcus sp. RHA1|Rep: Possible
3-hydroxybutyryl-CoA dehydrogenase - Rhodococcus sp.
(strain RHA1)
Length = 331
Score = 65.7 bits (153), Expect = 1e-09
Identities = 34/107 (31%), Positives = 59/107 (55%)
Frame = +2
Query: 401 RINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFASNTSSLSINEIAS 580
R+ +TD +EA + ADLV+EA+ E VK +++ + P HT+ A+N+S+L + A+
Sbjct: 80 RLTYSTDISEAVQHADLVIEAVSERPDVKTSVYETMAPHLPEHTMIATNSSTLLPQDFAA 139
Query: 581 VVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXG 721
R +K+ LHF N + + + ++ ET+ T E+G G
Sbjct: 140 ATGRPEKYCALHFANLIWKLNAVEIMAHPETARDTLIAATEFGIEIG 186
>UniRef50_A0PRD1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase FadB3;
n=1; Mycobacterium ulcerans Agy99|Rep:
3-hydroxybutyryl-CoA dehydrogenase FadB3 - Mycobacterium
ulcerans (strain Agy99)
Length = 294
Score = 65.7 bits (153), Expect = 1e-09
Identities = 53/170 (31%), Positives = 81/170 (47%), Gaps = 1/170 (0%)
Frame = +2
Query: 194 VTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNPQEV 373
V VIG G +G IA + A G V + + A+A + + NL K+ +D
Sbjct: 17 VAVIGAGTLGRRIALMFASRGGTVRIYARRAEQRAQATQYVADNLP----KLLQDRGF-- 70
Query: 374 EKFVNDSLGRINTATDA-AEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFASNT 550
+G + TATD A A + A L VE++ E + +K L+ Q+D AP TIFA+N+
Sbjct: 71 -----GEVGSV-TATDCLATALEGAWLAVESVPEKLEIKTALWGQIDQAAPPDTIFATNS 124
Query: 551 SSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMM 700
SS +A V+ K + HF+ P P L ++ ET T++
Sbjct: 125 SSFPSRLMADNVRDKTRLCNTHFYMP-PQFNALDLMSDGETDRGLLDTLL 173
>UniRef50_Q1RLR0 Cluster: LOC570274 protein; n=4; Clupeocephala|Rep:
LOC570274 protein - Danio rerio (Zebrafish) (Brachydanio
rerio)
Length = 327
Score = 65.3 bits (152), Expect = 1e-09
Identities = 55/196 (28%), Positives = 89/196 (45%), Gaps = 6/196 (3%)
Frame = +2
Query: 146 VRNFSNSSAMQSAI-KNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGT 322
V F N +AM S K +TV+G GL+G A V G V L D + A I
Sbjct: 4 VLTFVNETAMSSLKEKIITVVGSGLIGRSWAMVFLSGGYKVKLYDNKPGQASGAIAEIRK 63
Query: 323 NLSRVAK-KMYKDNPQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLF 499
L + + KM + N E+ L R+++ D +A A V E++ E++ K +F
Sbjct: 64 QLEELQQAKMLRGNLSATEQ-----LSRLSSHEDLQQALDGAFFVQESVFEDLEAKQSVF 118
Query: 500 KQLDGVAPSHTIFASNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSET-- 673
++ + I +S+TS L + + S V+ + + H NP +RL+ +V ET
Sbjct: 119 HAVEELVSESVILSSSTSCLMPSNVFSQVQNRTRCIVSHPVNPPYYVRLVELVPHPETLP 178
Query: 674 --SEATYKTMMEWGKS 715
E Y M + G++
Sbjct: 179 AVMEVAYSLMTDVGQA 194
>UniRef50_Q98LG2 Cluster: Mll1034 protein; n=5;
Alphaproteobacteria|Rep: Mll1034 protein - Rhizobium
loti (Mesorhizobium loti)
Length = 315
Score = 64.5 bits (150), Expect = 3e-09
Identities = 53/165 (32%), Positives = 79/165 (47%)
Frame = +2
Query: 191 NVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNPQE 370
NV ++G G +G A A+AG +V + D S A A+ I L +A N
Sbjct: 3 NVAIVGSGFIGRAWAISFARAGHDVRMWDQSPAATGGARDYIEGVLGDLAA-----NDLL 57
Query: 371 VEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFASNT 550
+ V+ LGRI T D AEA A V E EN+ VK ++F +D +A TI AS+T
Sbjct: 58 RGQSVDTVLGRIATVGDLAEALADAAHVQENTPENLDVKREVFSLIDRLAGPQTIIASST 117
Query: 551 SSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEAT 685
S+L ++ ++ + + +H NP ++ VV TS T
Sbjct: 118 SALLPSKFTDHLQGRHRCLVVHPINPPYLIPAAEVVPAPWTSAET 162
>UniRef50_Q0RVG8 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Rhodococcus sp. RHA1|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Rhodococcus sp. (strain RHA1)
Length = 288
Score = 64.5 bits (150), Expect = 3e-09
Identities = 56/181 (30%), Positives = 87/181 (48%), Gaps = 1/181 (0%)
Frame = +2
Query: 194 VTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNPQEV 373
++V G G+MG GIA V A AG V+L D D VA++ +P +
Sbjct: 6 ISVFGAGIMGRGIAVVLADAGHRVSLYDARAD---------------VAREAAAAHPN-I 49
Query: 374 EKFVNDSLGRINTATDAAEAS-KSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFASNT 550
E A+D EA+ + + L+ EA+VEN+ VK LF +++ + S T ASNT
Sbjct: 50 E------------ASDTIEAAVEGSSLLFEAVVENLEVKRDLFAEIERFSES-TPIASNT 96
Query: 551 SSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXGKTC 730
S+ + +E+A + + HFFNP V+ L+ VV +T + + GKT
Sbjct: 97 STFTPSELAKNLCEPGRLVIAHFFNPAEVVPLVEVVPSPDTRPDVVSAVTSALVAAGKTV 156
Query: 731 I 733
+
Sbjct: 157 V 157
>UniRef50_Q0FUQ2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2;
Alphaproteobacteria|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Roseovarius sp. HTCC2601
Length = 316
Score = 64.5 bits (150), Expect = 3e-09
Identities = 54/181 (29%), Positives = 91/181 (50%), Gaps = 5/181 (2%)
Frame = +2
Query: 185 IKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNP 364
++ + ++G G++G+ A V A++G +V + + S A + + ++L+ A + +D
Sbjct: 3 VRKIAILGSGVIGASWAIVYARSGCDVAIYERSEAFRDSAMQRLESSLASSAS-LLRDG- 60
Query: 365 QEVEKFVNDSLGRINTATDAAEASKS-ADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFA 541
+ V D L RI T D EA+ + AD V E IVEN+ K ++F L+ A I A
Sbjct: 61 ----ETVQDVLARI-TLHDTLEAAVAGADFVHECIVENLDSKRQIFAALNDAAEPEAILA 115
Query: 542 SNTSSLSINEIASVVKRKDKFGGLHFFNP---VPVMRLL-XVVKGSETSEATYKTMMEWG 709
S TSS ++ AS + +D+ +H P +PV + +E SE T M E G
Sbjct: 116 STTSSFPVSHFASDLACRDRCIIVHPATPPHLLPVTEICPAPFTSAEVSERTTAFMRECG 175
Query: 710 K 712
+
Sbjct: 176 Q 176
>UniRef50_Q97HK2 Cluster: 3-Hydroxyacyl-CoA dehydrogenase; n=1;
Clostridium acetobutylicum|Rep: 3-Hydroxyacyl-CoA
dehydrogenase - Clostridium acetobutylicum
Length = 379
Score = 64.1 bits (149), Expect = 3e-09
Identities = 45/180 (25%), Positives = 87/180 (48%)
Frame = +2
Query: 194 VTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNPQEV 373
+ +IG G MG I + V L+ + + + K SI L +K K N
Sbjct: 3 IGIIGKGKMGRDIFNYISMFDYKVILICRQAEQVEEVKSSIEKQL----RKKLKRNLITE 58
Query: 374 EKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFASNTS 553
E++ +S TD + K+ D+++EAI E+ +K + ++ + I A+NTS
Sbjct: 59 EEY--NSKKDAYKVTDNIQDLKNCDIIIEAIYEDEVLKQNILGDVEKIVKDECILATNTS 116
Query: 554 SLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEWGKSXGKTCI 733
S+ + + + +K++ GLHFF PV ++ + + + T +T++++ + GKT +
Sbjct: 117 SIPLEIVFAKCVKKERCLGLHFFFPVKIIDFVEINELRCTESRYVETIVQFLTTIGKTSL 176
>UniRef50_Q01UM7 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Solibacter usitatus Ellin6076|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Solibacter usitatus (strain Ellin6076)
Length = 794
Score = 64.1 bits (149), Expect = 3e-09
Identities = 46/177 (25%), Positives = 80/177 (45%), Gaps = 2/177 (1%)
Frame = +2
Query: 158 SNSSAMQSAIKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRV 337
S+ + I+ V+G G MG+ IA A AG V L+D++ A++K + ++
Sbjct: 16 SSGRSPAPVIRKAAVLGAGTMGARIAAHLANAGLPVVLLDMATAEGARSKIA-----AQA 70
Query: 338 AKKMYKDNPQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGV 517
+ + K P + + D D V+EA+ EN+ +K L +
Sbjct: 71 LEDLKKSKPAAFYDSAYAAHIIVGNFEDDMALLADCDWVIEAVTENLAIKQSLLDKAVPH 130
Query: 518 APSHTIFASNTSSLSINEIASVVKR--KDKFGGLHFFNPVPVMRLLXVVKGSETSEA 682
+ I +NTS L + +IA+ + + ++ G HFFNP MRLL ++ + A
Sbjct: 131 LKAGAILTTNTSGLPVAQIAAKLPADVRRRWFGTHFFNPPRYMRLLEIIPTPDADAA 187
>UniRef50_A4SW21 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor; n=1; Polynucleobacter sp.
QLW-P1DMWA-1|Rep: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor - Polynucleobacter sp.
QLW-P1DMWA-1
Length = 310
Score = 64.1 bits (149), Expect = 3e-09
Identities = 49/173 (28%), Positives = 77/173 (44%)
Frame = +2
Query: 185 IKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNP 364
+ V VIG G MG GIA G N L+ + ++I + + NP
Sbjct: 1 MSKVVVIGTGTMGIGIAAGFLAYGANTILLGRNPAKTTSCIEAIENCAASI-------NP 53
Query: 365 QEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFAS 544
+ S G I +D + DLV+E++ EN+G+K +F LD PSH S
Sbjct: 54 AWPQLGGALSTGSIADWSDWT----NTDLVIESVSENLGLKRLIFSDLDQRLPSHIPIGS 109
Query: 545 NTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMME 703
NTS I++I + + + H+F P ++ L+ VV G + KT+ +
Sbjct: 110 NTSGFPISDITASLPTAHRMFNTHYFMPAHIVPLVEVVLGKTSDPELAKTVCQ 162
>UniRef50_A3A5G7 Cluster: Putative uncharacterized protein; n=1;
Oryza sativa (japonica cultivar-group)|Rep: Putative
uncharacterized protein - Oryza sativa subsp. japonica
(Rice)
Length = 586
Score = 63.7 bits (148), Expect = 5e-09
Identities = 46/142 (32%), Positives = 72/142 (50%), Gaps = 3/142 (2%)
Frame = +2
Query: 185 IKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKK--MYKD 358
I+ V VIGGGLMGSGIA + +V L +V+ L + +K I NL + K+ + KD
Sbjct: 309 IRKVAVIGGGLMGSGIATALLVSNTSVVLKEVNPQFLQRGQKMIAANLEGLVKRGSLTKD 368
Query: 359 NPQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDG-VAPSHTI 535
+N ++ + A D ++ K D+V+EA++E I +K +F L+ A + T
Sbjct: 369 K-------MNKAMSLLKGALDYSD-FKDVDMVIEAVIEKIPLKQSIFSDLEKCFAVNRTF 420
Query: 536 FASNTSSLSINEIASVVKRKDK 601
F S + I V R D+
Sbjct: 421 FPYTQGSHLLVSIGIDVFRIDR 442
>UniRef50_Q67QQ5 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenase;
n=1; Symbiobacterium thermophilum|Rep: Putative
3-hydroxyacyl-CoA dehydrogenase - Symbiobacterium
thermophilum
Length = 190
Score = 63.3 bits (147), Expect = 6e-09
Identities = 45/148 (30%), Positives = 76/148 (51%)
Frame = +2
Query: 185 IKNVTVIGGGLMGSGIAQVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKKMYKDNP 364
++ +TVIGG + G IA + A+AG L + ALA+A + + L + ++
Sbjct: 1 MERITVIGGTVAGVEIAALMARAGYATCLHEPDQAALAEAGRRLQDRL--LGRQGEGGGA 58
Query: 365 QEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPSHTIFAS 544
V + + R+ + A A ADLV+EA ++ K +LF +LD AP+H I A+
Sbjct: 59 ASVAQLAAVRV-RLEAVPEVAVAD--ADLVIEASSVDLPGKRELFARLDSFAPAHAILAT 115
Query: 545 NTSSLSINEIASVVKRKDKFGGLHFFNP 628
+ ++S +A+ R D+ L FF+P
Sbjct: 116 CSPTISSAYLAAATSRPDRVVSLGFFSP 143
>UniRef50_Q0UZL9 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 308
Score = 63.3 bits (147), Expect = 6e-09
Identities = 46/189 (24%), Positives = 88/189 (46%), Gaps = 2/189 (1%)
Frame = +2
Query: 173 MQSAIKNVTVIGGGLMGSGIA--QVSAQAGQNVTLVDVSNDALAKAKKSIGTNLSRVAKK 346
M++ VT+IG G +G A ++ + +T+ D +D + T + K
Sbjct: 1 METTKIKVTLIGTGTIGLSFAAFHLAKLSPSQLTIYDTRSD--------LSTYIEEFLPK 52
Query: 347 MYKDNPQEVEKFVNDSLGRINTATDAAEASKSADLVVEAIVENIGVKHKLFKQLDGVAPS 526
++ + L I A EA + ++ E+ EN+ VK KL+K+++ AP+
Sbjct: 53 FFESGKSPAD------LSEIRLAVTLQEAVSDSHIIQESGPENLDVKRKLWKEVEKYAPN 106
Query: 527 HTIFASNTSSLSINEIASVVKRKDKFGGLHFFNPVPVMRLLXVVKGSETSEATYKTMMEW 706
+ S+TS + ++ A ++ K + +H +NP +M LL +V SETS+ ++
Sbjct: 107 DALLWSSTSGIPASQQAQDMQDKTRLLVVHPYNPPHIMPLLELVPSSETSDTVISRTQDF 166
Query: 707 GKSXGKTCI 733
+ G+ I
Sbjct: 167 WRERGRVPI 175
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 697,835,036
Number of Sequences: 1657284
Number of extensions: 13831366
Number of successful extensions: 43036
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 41065
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 42739
length of database: 575,637,011
effective HSP length: 99
effective length of database: 411,565,895
effective search space used: 60088620670
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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