Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P15_pT_E06
(738 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X05344-1|CAA28955.1| 412|Homo sapiens cathepsin D protein. 257 3e-68
M63138-1|AAA51922.1| 412|Homo sapiens cathepsin D protein. 257 3e-68
M11233-1|AAB59529.1| 412|Homo sapiens CTSD protein. 257 3e-68
CR456947-1|CAG33228.1| 412|Homo sapiens CTSD protein. 257 3e-68
BT020155-1|AAV38957.1| 412|Homo sapiens cathepsin D (lysosomal ... 257 3e-68
BT006910-1|AAP35556.1| 412|Homo sapiens cathepsin D (lysosomal ... 257 3e-68
BC016320-1|AAH16320.1| 412|Homo sapiens cathepsin D protein. 257 3e-68
BC017842-1|AAH17842.1| 420|Homo sapiens napsin A aspartic pepti... 242 8e-64
AF200345-1|AAF17081.1| 420|Homo sapiens aspartyl protease 4 pro... 242 8e-64
AF098484-1|AAD13215.1| 420|Homo sapiens napsin 1 precursor prot... 242 8e-64
AF090386-1|AAD04917.1| 420|Homo sapiens napsin A protein. 242 8e-64
BC111705-1|AAI11706.1| 464|Homo sapiens NAPSB protein protein. 230 5e-60
AF200344-1|AAF17080.1| 450|Homo sapiens aspartyl protease 3 pro... 230 5e-60
M84424-1|AAA52300.1| 396|Homo sapiens cathepsin E protein. 224 2e-58
J05036-1|AAA52130.1| 396|Homo sapiens CTSE protein. 224 2e-58
BX571818-4|CAH73264.1| 396|Homo sapiens cathepsin E protein. 224 2e-58
BC042537-1|AAH42537.1| 396|Homo sapiens cathepsin E protein. 224 2e-58
AJ250717-1|CAB82850.1| 396|Homo sapiens procathepsin E protein. 224 2e-58
X00063-1|CAA24937.1| 300|Homo sapiens protein ( Human kidney mR... 194 4e-49
M10152-1|AAD03461.1| 406|Homo sapiens renin protein. 193 5e-49
L00073-1|AAA60363.1| 406|Homo sapiens renin protein. 193 5e-49
CR536498-1|CAG38737.1| 406|Homo sapiens REN protein. 193 5e-49
BC047752-1|AAH47752.1| 406|Homo sapiens renin protein. 193 5e-49
BC033474-1|AAH33474.1| 406|Homo sapiens renin protein. 193 5e-49
AL592146-1|CAI16594.1| 406|Homo sapiens renin protein. 193 5e-49
AL592114-1|CAH71224.1| 406|Homo sapiens renin protein. 193 5e-49
AY436324-1|AAR03502.1| 403|Homo sapiens renin protein. 192 8e-49
M26901-1|AAA60364.1| 403|Homo sapiens renin protein. 191 3e-48
BC029055-1|AAH29055.1| 388|Homo sapiens pepsinogen 5, group I (... 188 2e-47
J00287-1|AAA98529.1| 388|Homo sapiens PEP protein. 187 4e-47
M26032-1|AAA60061.1| 388|Homo sapiens pepsinogen A protein. 185 1e-46
U75272-1|AAB18273.1| 388|Homo sapiens gastricsin protein. 167 4e-41
M23077-1|AAA60063.1| 388|Homo sapiens pepsinogen C protein. 167 4e-41
M18667-1|AAA60062.1| 385|Homo sapiens pepsinogen protein. 167 4e-41
J04443-1|AAA60074.1| 388|Homo sapiens pepsinogen protein. 167 4e-41
BC073740-1|AAH73740.1| 388|Homo sapiens progastricsin (pepsinog... 167 4e-41
AL365205-1|CAI13181.1| 388|Homo sapiens progastricsin (pepsinog... 167 4e-41
BX571818-5|CAH73265.1| 363|Homo sapiens cathepsin E protein. 101 4e-21
AJ250716-1|CAB82849.1| 363|Homo sapiens cathepsin E, alternativ... 101 4e-21
AL365205-2|CAI95135.1| 140|Homo sapiens progastricsin (pepsinog... 60 6e-09
AF188276-1|AAF35835.1| 468|Homo sapiens aspartyl protease protein. 50 7e-06
AK075539-1|BAC11682.1| 423|Homo sapiens protein ( Homo sapiens ... 49 2e-05
BC014453-1|AAH14453.1| 518|Homo sapiens beta-site APP-cleaving ... 48 3e-05
AY358927-1|AAQ89286.1| 518|Homo sapiens BACE2 protein. 48 3e-05
AL163285-1|CAB90554.1| 415|Homo sapiens beta-site APP-cleaving ... 48 3e-05
AF212252-1|AAG41783.1| 439|Homo sapiens CDA13 protein. 48 3e-05
AF204944-1|AAF26368.1| 518|Homo sapiens transmembrane aspartic ... 48 3e-05
AF200342-1|AAF17078.1| 518|Homo sapiens aspartyl protease 1 pro... 48 3e-05
AF200192-1|AAF13714.1| 518|Homo sapiens memapsin 1 protein. 48 3e-05
AF188277-1|AAF35836.1| 396|Homo sapiens aspartyl protease protein. 48 3e-05
AF178532-1|AAF29494.1| 518|Homo sapiens aspartyl protease protein. 48 3e-05
AF117892-1|AAD45240.1| 518|Homo sapiens aspartic-like protease ... 48 3e-05
AF050171-1|AAD45963.1| 518|Homo sapiens aspartyl protease protein. 48 3e-05
DQ007053-1|AAY16982.1| 501|Homo sapiens beta-site APP-cleaving ... 44 4e-04
BC065492-1|AAH65492.1| 501|Homo sapiens beta-site APP-cleaving ... 44 4e-04
BC036084-1|AAH36084.1| 501|Homo sapiens beta-site APP-cleaving ... 44 4e-04
AF204943-1|AAF26367.1| 501|Homo sapiens transmembrane aspartic ... 44 4e-04
AF201468-1|AAF18982.1| 501|Homo sapiens APP beta-secretase prot... 44 4e-04
AF200343-1|AAF17079.1| 501|Homo sapiens aspartyl protease 2 pro... 44 4e-04
AF200193-1|AAF13715.1| 488|Homo sapiens memapsin 2 protein. 44 4e-04
AF190725-1|AAF04142.1| 501|Homo sapiens beta-site APP cleaving ... 44 4e-04
AB177847-1|BAD66825.1| 396|Homo sapiens KIAA1149 splice variant... 44 4e-04
AB032975-1|BAA86463.2| 532|Homo sapiens KIAA1149 protein protein. 44 4e-04
AF338817-1|AAK38375.1| 457|Homo sapiens beta-site APP cleaving ... 35 0.35
AB050437-1|BAB40932.1| 457|Homo sapiens beta-site APP cleaving ... 35 0.35
AK125511-1|BAC86188.1| 559|Homo sapiens rome) (ELN). protein. 33 1.4
AK126042-1|BAC86409.1| 265|Homo sapiens protein ( Homo sapiens ... 32 2.5
Z97652-2|CAM26431.1| 1269|Homo sapiens Crm, cramped-like (Drosop... 30 10.0
U94332-1|AAB53709.1| 401|Homo sapiens osteoprotegerin protein. 30 10.0
BC146661-1|AAI46662.1| 686|Homo sapiens STIM2 protein protein. 30 10.0
BC030155-1|AAH30155.1| 401|Homo sapiens tumor necrosis factor r... 30 10.0
AY466112-1|AAR23265.1| 401|Homo sapiens tumor necrosis factor r... 30 10.0
AL162426-8|CAI41183.1| 520|Homo sapiens chromosome 9 open readi... 30 10.0
AL031708-1|CAM26357.1| 1269|Homo sapiens Crm, cramped-like (Dros... 30 10.0
AL031009-1|CAM26477.1| 1269|Homo sapiens Crm, cramped-like (Dros... 30 10.0
AK223155-1|BAD96875.1| 401|Homo sapiens osteoprotegerin precurs... 30 10.0
AF134187-1|AAF20168.1| 372|Homo sapiens osteoprotegerin protein. 30 10.0
AE006639-2|AAK61288.1| 1587|Homo sapiens unknown protein. 30 10.0
AB040915-1|BAA96006.1| 818|Homo sapiens KIAA1482 protein protein. 30 10.0
AB037847-1|BAA92664.2| 1066|Homo sapiens KIAA1426 protein protein. 30 10.0
AB008822-1|BAA32076.1| 401|Homo sapiens osteoclastogenesis inhi... 30 10.0
AB002146-1|BAA25910.1| 401|Homo sapiens osteoclastogenesis inhi... 30 10.0
>X05344-1|CAA28955.1| 412|Homo sapiens cathepsin D protein.
Length = 412
Score = 257 bits (630), Expect = 3e-68
Identities = 118/237 (49%), Positives = 157/237 (66%), Gaps = 2/237 (0%)
Frame = -2
Query: 725 VGGXKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFSTIAVDHVTPVFDNMVAQGLV-QPV 549
+GG KV RQ F EA +PG+ F+AAKFDGILGMA+ I+V++V PVFDN++ Q LV Q +
Sbjct: 169 LGGVKVERQVFGEATKQPGITFIAAKFDGILGMAYPRISVNNVLPVFDNLMQQKLVDQNI 228
Query: 548 FSFYLNRDPGATTXXXXXXXGSDPAHYRGDLVRVPLLRDTYWEFHMDSVNVNAS-RFCAQ 372
FSFYL+RDP A G+D +Y+G L + + R YW+ H+D V V + C +
Sbjct: 229 FSFYLSRDPDAQPGGELMLGGTDSKYYKGSLSYLNVTRKAYWQVHLDQVEVASGLTLCKE 288
Query: 371 GCSAIADTGTSLIAGPSKEVEALNAAVGATAIAFGQYVVDCSLIPHLPRVTFTIAGNDFT 192
GC AI DTGTSL+ GP EV L A+GA + G+Y++ C + LP +T + G +
Sbjct: 289 GCEAIVDTGTSLMVGPVDEVRELQKAIGAVPLIQGEYMIPCEKVSTLPAITLKLGGKGYK 348
Query: 191 LEGNDYVLRVAQFGHTVCLSGFMALDVPKPMGPLWILGDVFIGKYYTEFDAGNRQLG 21
L DY L+V+Q G T+CLSGFM +D+P P GPLWILGDVFIG+YYT FD N ++G
Sbjct: 349 LSPEDYTLKVSQAGKTLCLSGFMGMDIPPPSGPLWILGDVFIGRYYTVFDRDNNRVG 405
>M63138-1|AAA51922.1| 412|Homo sapiens cathepsin D protein.
Length = 412
Score = 257 bits (630), Expect = 3e-68
Identities = 118/237 (49%), Positives = 157/237 (66%), Gaps = 2/237 (0%)
Frame = -2
Query: 725 VGGXKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFSTIAVDHVTPVFDNMVAQGLV-QPV 549
+GG KV RQ F EA +PG+ F+AAKFDGILGMA+ I+V++V PVFDN++ Q LV Q +
Sbjct: 169 LGGVKVERQVFGEATKQPGITFIAAKFDGILGMAYPRISVNNVLPVFDNLMQQKLVDQNI 228
Query: 548 FSFYLNRDPGATTXXXXXXXGSDPAHYRGDLVRVPLLRDTYWEFHMDSVNVNAS-RFCAQ 372
FSFYL+RDP A G+D +Y+G L + + R YW+ H+D V V + C +
Sbjct: 229 FSFYLSRDPDAQPGGELMLGGTDSKYYKGSLSYLNVTRKAYWQVHLDQVEVASGLTLCKE 288
Query: 371 GCSAIADTGTSLIAGPSKEVEALNAAVGATAIAFGQYVVDCSLIPHLPRVTFTIAGNDFT 192
GC AI DTGTSL+ GP EV L A+GA + G+Y++ C + LP +T + G +
Sbjct: 289 GCEAIVDTGTSLMVGPVDEVRELQKAIGAVPLIQGEYMIPCEKVSTLPAITLKLGGKGYK 348
Query: 191 LEGNDYVLRVAQFGHTVCLSGFMALDVPKPMGPLWILGDVFIGKYYTEFDAGNRQLG 21
L DY L+V+Q G T+CLSGFM +D+P P GPLWILGDVFIG+YYT FD N ++G
Sbjct: 349 LSPEDYTLKVSQAGKTLCLSGFMGMDIPPPSGPLWILGDVFIGRYYTVFDRDNNRVG 405
>M11233-1|AAB59529.1| 412|Homo sapiens CTSD protein.
Length = 412
Score = 257 bits (630), Expect = 3e-68
Identities = 118/237 (49%), Positives = 157/237 (66%), Gaps = 2/237 (0%)
Frame = -2
Query: 725 VGGXKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFSTIAVDHVTPVFDNMVAQGLV-QPV 549
+GG KV RQ F EA +PG+ F+AAKFDGILGMA+ I+V++V PVFDN++ Q LV Q +
Sbjct: 169 LGGVKVERQVFGEATKQPGITFIAAKFDGILGMAYPRISVNNVLPVFDNLMQQKLVDQNI 228
Query: 548 FSFYLNRDPGATTXXXXXXXGSDPAHYRGDLVRVPLLRDTYWEFHMDSVNVNAS-RFCAQ 372
FSFYL+RDP A G+D +Y+G L + + R YW+ H+D V V + C +
Sbjct: 229 FSFYLSRDPDAQPGGELMLGGTDSKYYKGSLSYLNVTRKAYWQVHLDQVEVASGLTLCKE 288
Query: 371 GCSAIADTGTSLIAGPSKEVEALNAAVGATAIAFGQYVVDCSLIPHLPRVTFTIAGNDFT 192
GC AI DTGTSL+ GP EV L A+GA + G+Y++ C + LP +T + G +
Sbjct: 289 GCEAIVDTGTSLMVGPVDEVRELQKAIGAVPLIQGEYMIPCEKVSTLPAITLKLGGKGYK 348
Query: 191 LEGNDYVLRVAQFGHTVCLSGFMALDVPKPMGPLWILGDVFIGKYYTEFDAGNRQLG 21
L DY L+V+Q G T+CLSGFM +D+P P GPLWILGDVFIG+YYT FD N ++G
Sbjct: 349 LSPEDYTLKVSQAGKTLCLSGFMGMDIPPPSGPLWILGDVFIGRYYTVFDRDNNRVG 405
>CR456947-1|CAG33228.1| 412|Homo sapiens CTSD protein.
Length = 412
Score = 257 bits (630), Expect = 3e-68
Identities = 118/237 (49%), Positives = 157/237 (66%), Gaps = 2/237 (0%)
Frame = -2
Query: 725 VGGXKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFSTIAVDHVTPVFDNMVAQGLV-QPV 549
+GG KV RQ F EA +PG+ F+AAKFDGILGMA+ I+V++V PVFDN++ Q LV Q +
Sbjct: 169 LGGVKVERQVFGEATKQPGITFIAAKFDGILGMAYPRISVNNVLPVFDNLMQQKLVDQNI 228
Query: 548 FSFYLNRDPGATTXXXXXXXGSDPAHYRGDLVRVPLLRDTYWEFHMDSVNVNAS-RFCAQ 372
FSFYL+RDP A G+D +Y+G L + + R YW+ H+D V V + C +
Sbjct: 229 FSFYLSRDPDAQPGGELMLGGTDSKYYKGSLSYLNVTRKAYWQVHLDQVEVASGLTLCKE 288
Query: 371 GCSAIADTGTSLIAGPSKEVEALNAAVGATAIAFGQYVVDCSLIPHLPRVTFTIAGNDFT 192
GC AI DTGTSL+ GP EV L A+GA + G+Y++ C + LP +T + G +
Sbjct: 289 GCEAIVDTGTSLMVGPVDEVRELQKAIGAVPLIQGEYMIPCEKVSTLPAITLKLGGKGYK 348
Query: 191 LEGNDYVLRVAQFGHTVCLSGFMALDVPKPMGPLWILGDVFIGKYYTEFDAGNRQLG 21
L DY L+V+Q G T+CLSGFM +D+P P GPLWILGDVFIG+YYT FD N ++G
Sbjct: 349 LSPEDYTLKVSQAGKTLCLSGFMGMDIPPPSGPLWILGDVFIGRYYTVFDRDNNRVG 405
>BT020155-1|AAV38957.1| 412|Homo sapiens cathepsin D (lysosomal
aspartyl protease) protein.
Length = 412
Score = 257 bits (630), Expect = 3e-68
Identities = 118/237 (49%), Positives = 157/237 (66%), Gaps = 2/237 (0%)
Frame = -2
Query: 725 VGGXKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFSTIAVDHVTPVFDNMVAQGLV-QPV 549
+GG KV RQ F EA +PG+ F+AAKFDGILGMA+ I+V++V PVFDN++ Q LV Q +
Sbjct: 169 LGGVKVERQVFGEATKQPGITFIAAKFDGILGMAYPRISVNNVLPVFDNLMQQKLVDQNI 228
Query: 548 FSFYLNRDPGATTXXXXXXXGSDPAHYRGDLVRVPLLRDTYWEFHMDSVNVNAS-RFCAQ 372
FSFYL+RDP A G+D +Y+G L + + R YW+ H+D V V + C +
Sbjct: 229 FSFYLSRDPDAQPGGELMLGGTDSKYYKGSLSYLNVTRKAYWQVHLDQVEVASGLTLCKE 288
Query: 371 GCSAIADTGTSLIAGPSKEVEALNAAVGATAIAFGQYVVDCSLIPHLPRVTFTIAGNDFT 192
GC AI DTGTSL+ GP EV L A+GA + G+Y++ C + LP +T + G +
Sbjct: 289 GCEAIVDTGTSLMVGPVDEVRELQKAIGAVPLIQGEYMIPCEKVSTLPAITLKLGGKGYK 348
Query: 191 LEGNDYVLRVAQFGHTVCLSGFMALDVPKPMGPLWILGDVFIGKYYTEFDAGNRQLG 21
L DY L+V+Q G T+CLSGFM +D+P P GPLWILGDVFIG+YYT FD N ++G
Sbjct: 349 LSPEDYTLKVSQAGKTLCLSGFMGMDIPPPSGPLWILGDVFIGRYYTVFDRDNNRVG 405
>BT006910-1|AAP35556.1| 412|Homo sapiens cathepsin D (lysosomal
aspartyl protease) protein.
Length = 412
Score = 257 bits (630), Expect = 3e-68
Identities = 118/237 (49%), Positives = 157/237 (66%), Gaps = 2/237 (0%)
Frame = -2
Query: 725 VGGXKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFSTIAVDHVTPVFDNMVAQGLV-QPV 549
+GG KV RQ F EA +PG+ F+AAKFDGILGMA+ I+V++V PVFDN++ Q LV Q +
Sbjct: 169 LGGVKVERQVFGEATKQPGITFIAAKFDGILGMAYPRISVNNVLPVFDNLMQQKLVDQNI 228
Query: 548 FSFYLNRDPGATTXXXXXXXGSDPAHYRGDLVRVPLLRDTYWEFHMDSVNVNAS-RFCAQ 372
FSFYL+RDP A G+D +Y+G L + + R YW+ H+D V V + C +
Sbjct: 229 FSFYLSRDPDAQPGGELMLGGTDSKYYKGSLSYLNVTRKAYWQVHLDQVEVASGLTLCKE 288
Query: 371 GCSAIADTGTSLIAGPSKEVEALNAAVGATAIAFGQYVVDCSLIPHLPRVTFTIAGNDFT 192
GC AI DTGTSL+ GP EV L A+GA + G+Y++ C + LP +T + G +
Sbjct: 289 GCEAIVDTGTSLMVGPVDEVRELQKAIGAVPLIQGEYMIPCEKVSTLPAITLKLGGKGYK 348
Query: 191 LEGNDYVLRVAQFGHTVCLSGFMALDVPKPMGPLWILGDVFIGKYYTEFDAGNRQLG 21
L DY L+V+Q G T+CLSGFM +D+P P GPLWILGDVFIG+YYT FD N ++G
Sbjct: 349 LSPEDYTLKVSQAGKTLCLSGFMGMDIPPPSGPLWILGDVFIGRYYTVFDRDNNRVG 405
>BC016320-1|AAH16320.1| 412|Homo sapiens cathepsin D protein.
Length = 412
Score = 257 bits (630), Expect = 3e-68
Identities = 118/237 (49%), Positives = 157/237 (66%), Gaps = 2/237 (0%)
Frame = -2
Query: 725 VGGXKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFSTIAVDHVTPVFDNMVAQGLV-QPV 549
+GG KV RQ F EA +PG+ F+AAKFDGILGMA+ I+V++V PVFDN++ Q LV Q +
Sbjct: 169 LGGVKVERQVFGEATKQPGITFIAAKFDGILGMAYPRISVNNVLPVFDNLMQQKLVDQNI 228
Query: 548 FSFYLNRDPGATTXXXXXXXGSDPAHYRGDLVRVPLLRDTYWEFHMDSVNVNAS-RFCAQ 372
FSFYL+RDP A G+D +Y+G L + + R YW+ H+D V V + C +
Sbjct: 229 FSFYLSRDPDAQPGGELMLGGTDSKYYKGSLSYLNVTRKAYWQVHLDQVEVASGLTLCKE 288
Query: 371 GCSAIADTGTSLIAGPSKEVEALNAAVGATAIAFGQYVVDCSLIPHLPRVTFTIAGNDFT 192
GC AI DTGTSL+ GP EV L A+GA + G+Y++ C + LP +T + G +
Sbjct: 289 GCEAIVDTGTSLMVGPVDEVRELQKAIGAVPLIQGEYMIPCEKVSTLPAITLKLGGKGYK 348
Query: 191 LEGNDYVLRVAQFGHTVCLSGFMALDVPKPMGPLWILGDVFIGKYYTEFDAGNRQLG 21
L DY L+V+Q G T+CLSGFM +D+P P GPLWILGDVFIG+YYT FD N ++G
Sbjct: 349 LSPEDYTLKVSQAGKTLCLSGFMGMDIPPPSGPLWILGDVFIGRYYTVFDRDNNRVG 405
>BC017842-1|AAH17842.1| 420|Homo sapiens napsin A aspartic
peptidase protein.
Length = 420
Score = 242 bits (593), Expect = 8e-64
Identities = 119/243 (48%), Positives = 154/243 (63%), Gaps = 2/243 (0%)
Frame = -2
Query: 737 DDVTVGGXKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFSTIAVDHVTPVFDNMVAQGLV 558
D +T+GG K F EA+ EP L F A FDGILG+ F ++V+ V P D +V QGL+
Sbjct: 153 DKLTIGGIKGASVIFGEALWEPSLVFAFAHFDGILGLGFPILSVEGVRPPMDVLVEQGLL 212
Query: 557 -QPVFSFYLNRDPGATTXXXXXXXGSDPAHYRGDLVRVPLLRDTYWEFHMDSVNVNAS-R 384
+PVFSFYLNRDP GSDPAHY L VP+ YW+ HM+ V V
Sbjct: 213 DKPVFSFYLNRDPEEPDGGELVLGGSDPAHYIPPLTFVPVTVPAYWQIHMERVKVGPGLT 272
Query: 383 FCAQGCSAIADTGTSLIAGPSKEVEALNAAVGATAIAFGQYVVDCSLIPHLPRVTFTIAG 204
CA+GC+AI DTGTSLI GP++E+ AL+AA+G + G+Y++ CS IP LP V+F + G
Sbjct: 273 LCAKGCAAILDTGTSLITGPTEEIRALHAAIGGIPLLAGEYIILCSEIPKLPAVSFLLGG 332
Query: 203 NDFTLEGNDYVLRVAQFGHTVCLSGFMALDVPKPMGPLWILGDVFIGKYYTEFDAGNRQL 24
F L +DYV++ + G +CLSGF ALDVP P GP WILGDVF+G Y FD G+ +
Sbjct: 333 VWFNLTAHDYVIQTTRNGVRLCLSGFQALDVPPPAGPFWILGDVFLGTYVAVFDRGDMKS 392
Query: 23 GSR 15
+R
Sbjct: 393 SAR 395
>AF200345-1|AAF17081.1| 420|Homo sapiens aspartyl protease 4
protein.
Length = 420
Score = 242 bits (593), Expect = 8e-64
Identities = 119/243 (48%), Positives = 154/243 (63%), Gaps = 2/243 (0%)
Frame = -2
Query: 737 DDVTVGGXKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFSTIAVDHVTPVFDNMVAQGLV 558
D +T+GG K F EA+ EP L F A FDGILG+ F ++V+ V P D +V QGL+
Sbjct: 153 DKLTIGGIKGASVIFGEALWEPSLVFAFAHFDGILGLGFPILSVEGVRPPMDVLVEQGLL 212
Query: 557 -QPVFSFYLNRDPGATTXXXXXXXGSDPAHYRGDLVRVPLLRDTYWEFHMDSVNVNAS-R 384
+PVFSFYLNRDP GSDPAHY L VP+ YW+ HM+ V V
Sbjct: 213 DKPVFSFYLNRDPEEPDGGELVLGGSDPAHYIPPLTFVPVTVPAYWQIHMERVKVGPGLT 272
Query: 383 FCAQGCSAIADTGTSLIAGPSKEVEALNAAVGATAIAFGQYVVDCSLIPHLPRVTFTIAG 204
CA+GC+AI DTGTSLI GP++E+ AL+AA+G + G+Y++ CS IP LP V+F + G
Sbjct: 273 LCAKGCAAILDTGTSLITGPTEEIRALHAAIGGIPLLAGEYIILCSEIPKLPAVSFLLGG 332
Query: 203 NDFTLEGNDYVLRVAQFGHTVCLSGFMALDVPKPMGPLWILGDVFIGKYYTEFDAGNRQL 24
F L +DYV++ + G +CLSGF ALDVP P GP WILGDVF+G Y FD G+ +
Sbjct: 333 VWFNLTAHDYVIQTTRNGVRLCLSGFQALDVPPPAGPFWILGDVFLGTYVAVFDRGDMKS 392
Query: 23 GSR 15
+R
Sbjct: 393 SAR 395
>AF098484-1|AAD13215.1| 420|Homo sapiens napsin 1 precursor
protein.
Length = 420
Score = 242 bits (593), Expect = 8e-64
Identities = 119/243 (48%), Positives = 154/243 (63%), Gaps = 2/243 (0%)
Frame = -2
Query: 737 DDVTVGGXKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFSTIAVDHVTPVFDNMVAQGLV 558
D +T+GG K F EA+ EP L F A FDGILG+ F ++V+ V P D +V QGL+
Sbjct: 153 DKLTIGGIKGASVIFGEALWEPSLVFAFAHFDGILGLGFPILSVEGVRPPMDVLVEQGLL 212
Query: 557 -QPVFSFYLNRDPGATTXXXXXXXGSDPAHYRGDLVRVPLLRDTYWEFHMDSVNVNAS-R 384
+PVFSFYLNRDP GSDPAHY L VP+ YW+ HM+ V V
Sbjct: 213 DKPVFSFYLNRDPEEPDGGELVLGGSDPAHYIPPLTFVPVTVPAYWQIHMERVKVGPGLT 272
Query: 383 FCAQGCSAIADTGTSLIAGPSKEVEALNAAVGATAIAFGQYVVDCSLIPHLPRVTFTIAG 204
CA+GC+AI DTGTSLI GP++E+ AL+AA+G + G+Y++ CS IP LP V+F + G
Sbjct: 273 LCAKGCAAILDTGTSLITGPTEEIRALHAAIGGIPLLAGEYIILCSEIPKLPAVSFLLGG 332
Query: 203 NDFTLEGNDYVLRVAQFGHTVCLSGFMALDVPKPMGPLWILGDVFIGKYYTEFDAGNRQL 24
F L +DYV++ + G +CLSGF ALDVP P GP WILGDVF+G Y FD G+ +
Sbjct: 333 VWFNLTAHDYVIQTTRNGVRLCLSGFQALDVPPPAGPFWILGDVFLGTYVAVFDRGDMKS 392
Query: 23 GSR 15
+R
Sbjct: 393 SAR 395
>AF090386-1|AAD04917.1| 420|Homo sapiens napsin A protein.
Length = 420
Score = 242 bits (593), Expect = 8e-64
Identities = 119/243 (48%), Positives = 154/243 (63%), Gaps = 2/243 (0%)
Frame = -2
Query: 737 DDVTVGGXKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFSTIAVDHVTPVFDNMVAQGLV 558
D +T+GG K F EA+ EP L F A FDGILG+ F ++V+ V P D +V QGL+
Sbjct: 153 DKLTIGGIKGASVIFGEALWEPSLVFAFAHFDGILGLGFPILSVEGVRPPMDVLVEQGLL 212
Query: 557 -QPVFSFYLNRDPGATTXXXXXXXGSDPAHYRGDLVRVPLLRDTYWEFHMDSVNVNAS-R 384
+PVFSFYLNRDP GSDPAHY L VP+ YW+ HM+ V V
Sbjct: 213 DKPVFSFYLNRDPEEPDGGELVLGGSDPAHYIPPLTFVPVTVPAYWQIHMERVKVGPGLT 272
Query: 383 FCAQGCSAIADTGTSLIAGPSKEVEALNAAVGATAIAFGQYVVDCSLIPHLPRVTFTIAG 204
CA+GC+AI DTGTSLI GP++E+ AL+AA+G + G+Y++ CS IP LP V+F + G
Sbjct: 273 LCAKGCAAILDTGTSLITGPTEEIRALHAAIGGIPLLAGEYIILCSEIPKLPAVSFLLGG 332
Query: 203 NDFTLEGNDYVLRVAQFGHTVCLSGFMALDVPKPMGPLWILGDVFIGKYYTEFDAGNRQL 24
F L +DYV++ + G +CLSGF ALDVP P GP WILGDVF+G Y FD G+ +
Sbjct: 333 VWFNLTAHDYVIQTTRNGVRLCLSGFQALDVPPPAGPFWILGDVFLGTYVAVFDRGDMKS 392
Query: 23 GSR 15
+R
Sbjct: 393 SAR 395
>BC111705-1|AAI11706.1| 464|Homo sapiens NAPSB protein protein.
Length = 464
Score = 230 bits (562), Expect = 5e-60
Identities = 114/243 (46%), Positives = 151/243 (62%), Gaps = 2/243 (0%)
Frame = -2
Query: 737 DDVTVGGXKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFSTIAVDHVTPVFDNMVAQGLV 558
D +T+GG K F EA+ E L F ++ DGILG+ F ++V+ V P D +V QGL+
Sbjct: 149 DKLTIGGIKGASVIFGEALWESSLVFTVSRPDGILGLGFPILSVEGVRPPLDVLVEQGLL 208
Query: 557 -QPVFSFYLNRDPGATTXXXXXXXGSDPAHYRGDLVRVPLLRDTYWEFHMDSVNVNAS-R 384
+PVFSFY NRDP GSDPAHY L VP+ YW+ HM+ V V +
Sbjct: 209 DKPVFSFYFNRDPEVADGGELVLGGSDPAHYIPPLTFVPVTVPAYWQIHMERVKVGSRLT 268
Query: 383 FCAQGCSAIADTGTSLIAGPSKEVEALNAAVGATAIAFGQYVVDCSLIPHLPRVTFTIAG 204
CAQGC+AI DTGT +I GP++E+ AL+AA+G + G+Y++ CS IP LP V+ I G
Sbjct: 269 LCAQGCAAILDTGTPVIVGPTEEIRALHAAIGGIPLLAGEYIIRCSEIPKLPAVSLLIGG 328
Query: 203 NDFTLEGNDYVLRVAQFGHTVCLSGFMALDVPKPMGPLWILGDVFIGKYYTEFDAGNRQL 24
F L DYV++ AQ +CLSGF ALD+ P P+WILGDVF+G Y T FD G+ +
Sbjct: 329 VWFNLTAQDYVIQFAQGDVRLCLSGFRALDIASPPVPVWILGDVFLGAYVTVFDRGDMKS 388
Query: 23 GSR 15
G+R
Sbjct: 389 GAR 391
>AF200344-1|AAF17080.1| 450|Homo sapiens aspartyl protease 3
protein.
Length = 450
Score = 230 bits (562), Expect = 5e-60
Identities = 114/243 (46%), Positives = 151/243 (62%), Gaps = 2/243 (0%)
Frame = -2
Query: 737 DDVTVGGXKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFSTIAVDHVTPVFDNMVAQGLV 558
D +T+GG K F EA+ E L F ++ DGILG+ F ++V+ V P D +V QGL+
Sbjct: 153 DKLTIGGIKGASVIFGEALWESSLVFTVSRPDGILGLGFPILSVEGVRPPLDVLVEQGLL 212
Query: 557 -QPVFSFYLNRDPGATTXXXXXXXGSDPAHYRGDLVRVPLLRDTYWEFHMDSVNVNAS-R 384
+PVFSFY NRDP GSDPAHY L VP+ YW+ HM+ V V +
Sbjct: 213 DKPVFSFYFNRDPEVADGGELVLGGSDPAHYIPPLTFVPVTVPAYWQIHMERVKVGSRLT 272
Query: 383 FCAQGCSAIADTGTSLIAGPSKEVEALNAAVGATAIAFGQYVVDCSLIPHLPRVTFTIAG 204
CAQGC+AI DTGT +I GP++E+ AL+AA+G + G+Y++ CS IP LP V+ I G
Sbjct: 273 LCAQGCAAILDTGTPVIVGPTEEIRALHAAIGGIPLLAGEYIIRCSEIPKLPAVSLLIGG 332
Query: 203 NDFTLEGNDYVLRVAQFGHTVCLSGFMALDVPKPMGPLWILGDVFIGKYYTEFDAGNRQL 24
F L DYV++ AQ +CLSGF ALD+ P P+WILGDVF+G Y T FD G+ +
Sbjct: 333 VWFNLTAQDYVIQFAQGDVRLCLSGFRALDIASPPVPVWILGDVFLGAYVTVFDRGDMKS 392
Query: 23 GSR 15
G+R
Sbjct: 393 GAR 395
>M84424-1|AAA52300.1| 396|Homo sapiens cathepsin E protein.
Length = 396
Score = 224 bits (548), Expect = 2e-58
Identities = 112/244 (45%), Positives = 153/244 (62%), Gaps = 2/244 (0%)
Frame = -2
Query: 737 DDVTVGGXKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFSTIAVDHVTPVFDNMVAQGLV 558
D V+V G V Q F E+V+EPG FV A+FDGILG+ + ++AV VTPVFDNM+AQ LV
Sbjct: 151 DQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGILGLGYPSLAVGGVTPVFDNMMAQNLV 210
Query: 557 Q-PVFSFYLNRDPGATTXXXXXXXGSDPAHYRGDLVRVPLLRDTYWEFHMDSVNVNAS-R 384
P+FS Y++ +P G D +H+ G L VP+ + YW+ +D++ V +
Sbjct: 211 DLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSLNWVPVTKQAYWQIALDNIQVGGTVM 270
Query: 383 FCAQGCSAIADTGTSLIAGPSKEVEALNAAVGATAIAFGQYVVDCSLIPHLPRVTFTIAG 204
FC++GC AI DTGTSLI GPS +++ L A+GA + G+Y V+C+ + +P VTFTI G
Sbjct: 271 FCSEGCQAIVDTGTSLITGPSDKIKQLQNAIGAAPVD-GEYAVECANLNVMPDVTFTING 329
Query: 203 NDFTLEGNDYVLRVAQFGHTVCLSGFMALDVPKPMGPLWILGDVFIGKYYTEFDAGNRQL 24
+TL Y L G C SGF LD+ P GPLWILGDVFI ++Y+ FD GN ++
Sbjct: 330 VPYTLSPTAYTLLDFVDGMQFCSSGFQGLDIHPPAGPLWILGDVFIRQFYSVFDRGNNRV 389
Query: 23 GSRP 12
G P
Sbjct: 390 GLAP 393
>J05036-1|AAA52130.1| 396|Homo sapiens CTSE protein.
Length = 396
Score = 224 bits (548), Expect = 2e-58
Identities = 112/244 (45%), Positives = 153/244 (62%), Gaps = 2/244 (0%)
Frame = -2
Query: 737 DDVTVGGXKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFSTIAVDHVTPVFDNMVAQGLV 558
D V+V G V Q F E+V+EPG FV A+FDGILG+ + ++AV VTPVFDNM+AQ LV
Sbjct: 151 DQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGILGLGYPSLAVGGVTPVFDNMMAQNLV 210
Query: 557 Q-PVFSFYLNRDPGATTXXXXXXXGSDPAHYRGDLVRVPLLRDTYWEFHMDSVNVNAS-R 384
P+FS Y++ +P G D +H+ G L VP+ + YW+ +D++ V +
Sbjct: 211 DLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSLNWVPVTKQAYWQIALDNIQVGGTVM 270
Query: 383 FCAQGCSAIADTGTSLIAGPSKEVEALNAAVGATAIAFGQYVVDCSLIPHLPRVTFTIAG 204
FC++GC AI DTGTSLI GPS +++ L A+GA + G+Y V+C+ + +P VTFTI G
Sbjct: 271 FCSEGCQAIVDTGTSLITGPSDKIKQLQNAIGAAPVD-GEYAVECANLNVMPDVTFTING 329
Query: 203 NDFTLEGNDYVLRVAQFGHTVCLSGFMALDVPKPMGPLWILGDVFIGKYYTEFDAGNRQL 24
+TL Y L G C SGF LD+ P GPLWILGDVFI ++Y+ FD GN ++
Sbjct: 330 VPYTLSPTAYTLLDFVDGMQFCSSGFQGLDIHPPAGPLWILGDVFIRQFYSVFDRGNNRV 389
Query: 23 GSRP 12
G P
Sbjct: 390 GLAP 393
>BX571818-4|CAH73264.1| 396|Homo sapiens cathepsin E protein.
Length = 396
Score = 224 bits (548), Expect = 2e-58
Identities = 112/244 (45%), Positives = 153/244 (62%), Gaps = 2/244 (0%)
Frame = -2
Query: 737 DDVTVGGXKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFSTIAVDHVTPVFDNMVAQGLV 558
D V+V G V Q F E+V+EPG FV A+FDGILG+ + ++AV VTPVFDNM+AQ LV
Sbjct: 151 DQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGILGLGYPSLAVGGVTPVFDNMMAQNLV 210
Query: 557 Q-PVFSFYLNRDPGATTXXXXXXXGSDPAHYRGDLVRVPLLRDTYWEFHMDSVNVNAS-R 384
P+FS Y++ +P G D +H+ G L VP+ + YW+ +D++ V +
Sbjct: 211 DLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSLNWVPVTKQAYWQIALDNIQVGGTVM 270
Query: 383 FCAQGCSAIADTGTSLIAGPSKEVEALNAAVGATAIAFGQYVVDCSLIPHLPRVTFTIAG 204
FC++GC AI DTGTSLI GPS +++ L A+GA + G+Y V+C+ + +P VTFTI G
Sbjct: 271 FCSEGCQAIVDTGTSLITGPSDKIKQLQNAIGAAPVD-GEYAVECANLNVMPDVTFTING 329
Query: 203 NDFTLEGNDYVLRVAQFGHTVCLSGFMALDVPKPMGPLWILGDVFIGKYYTEFDAGNRQL 24
+TL Y L G C SGF LD+ P GPLWILGDVFI ++Y+ FD GN ++
Sbjct: 330 VPYTLSPTAYTLLDFVDGMQFCSSGFQGLDIHPPAGPLWILGDVFIRQFYSVFDRGNNRV 389
Query: 23 GSRP 12
G P
Sbjct: 390 GLAP 393
>BC042537-1|AAH42537.1| 396|Homo sapiens cathepsin E protein.
Length = 396
Score = 224 bits (548), Expect = 2e-58
Identities = 112/244 (45%), Positives = 153/244 (62%), Gaps = 2/244 (0%)
Frame = -2
Query: 737 DDVTVGGXKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFSTIAVDHVTPVFDNMVAQGLV 558
D V+V G V Q F E+V+EPG FV A+FDGILG+ + ++AV VTPVFDNM+AQ LV
Sbjct: 151 DQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGILGLGYPSLAVGGVTPVFDNMMAQNLV 210
Query: 557 Q-PVFSFYLNRDPGATTXXXXXXXGSDPAHYRGDLVRVPLLRDTYWEFHMDSVNVNAS-R 384
P+FS Y++ +P G D +H+ G L VP+ + YW+ +D++ V +
Sbjct: 211 DLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSLNWVPVTKQAYWQIALDNIQVGGTVM 270
Query: 383 FCAQGCSAIADTGTSLIAGPSKEVEALNAAVGATAIAFGQYVVDCSLIPHLPRVTFTIAG 204
FC++GC AI DTGTSLI GPS +++ L A+GA + G+Y V+C+ + +P VTFTI G
Sbjct: 271 FCSEGCQAIVDTGTSLITGPSDKIKQLQNAIGAAPVD-GEYAVECANLNVMPDVTFTING 329
Query: 203 NDFTLEGNDYVLRVAQFGHTVCLSGFMALDVPKPMGPLWILGDVFIGKYYTEFDAGNRQL 24
+TL Y L G C SGF LD+ P GPLWILGDVFI ++Y+ FD GN ++
Sbjct: 330 VPYTLSPTAYTLLDFVDGMQFCSSGFQGLDIHPPAGPLWILGDVFIRQFYSVFDRGNNRV 389
Query: 23 GSRP 12
G P
Sbjct: 390 GLAP 393
>AJ250717-1|CAB82850.1| 396|Homo sapiens procathepsin E protein.
Length = 396
Score = 224 bits (548), Expect = 2e-58
Identities = 112/244 (45%), Positives = 153/244 (62%), Gaps = 2/244 (0%)
Frame = -2
Query: 737 DDVTVGGXKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFSTIAVDHVTPVFDNMVAQGLV 558
D V+V G V Q F E+V+EPG FV A+FDGILG+ + ++AV VTPVFDNM+AQ LV
Sbjct: 151 DQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGILGLGYPSLAVGGVTPVFDNMMAQNLV 210
Query: 557 Q-PVFSFYLNRDPGATTXXXXXXXGSDPAHYRGDLVRVPLLRDTYWEFHMDSVNVNAS-R 384
P+FS Y++ +P G D +H+ G L VP+ + YW+ +D++ V +
Sbjct: 211 DLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSLNWVPVTKQAYWQIALDNIQVGGTVM 270
Query: 383 FCAQGCSAIADTGTSLIAGPSKEVEALNAAVGATAIAFGQYVVDCSLIPHLPRVTFTIAG 204
FC++GC AI DTGTSLI GPS +++ L A+GA + G+Y V+C+ + +P VTFTI G
Sbjct: 271 FCSEGCQAIVDTGTSLITGPSDKIKQLQNAIGAAPVD-GEYAVECANLNVMPDVTFTING 329
Query: 203 NDFTLEGNDYVLRVAQFGHTVCLSGFMALDVPKPMGPLWILGDVFIGKYYTEFDAGNRQL 24
+TL Y L G C SGF LD+ P GPLWILGDVFI ++Y+ FD GN ++
Sbjct: 330 VPYTLSPTAYTLLDFVDGMQFCSSGFQGLDIHPPAGPLWILGDVFIRQFYSVFDRGNNRV 389
Query: 23 GSRP 12
G P
Sbjct: 390 GLAP 393
>X00063-1|CAA24937.1| 300|Homo sapiens protein ( Human kidney mRNA
fragment for renin (aa 105-401). ).
Length = 300
Score = 194 bits (472), Expect = 4e-49
Identities = 97/243 (39%), Positives = 138/243 (56%), Gaps = 4/243 (1%)
Frame = -2
Query: 737 DDVTVGGXKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFSTIAVDHVTPVFDNMVAQGLV 558
D +TVGG V Q F E P L F+ A+FDG++GM F A+ VTP+FDN+++QG++
Sbjct: 54 DIITVGGITVT-QMFGEVTEMPALPFMLAEFDGVVGMGFIEQAIGRVTPIFDNIISQGVL 112
Query: 557 -QPVFSFYLNRDP--GATTXXXXXXXGSDPAHYRGDLVRVPLLRDTYWEFHMDSVNVNAS 387
+ VFSFY NRD + GSDP HY G+ + L++ W+ M V+V +S
Sbjct: 113 KEDVFSFYYNRDSENSQSLGGQIVLGGSDPQHYEGNFHYINLIKTGVWQIQMKGVSVGSS 172
Query: 386 RF-CAQGCSAIADTGTSLIAGPSKEVEALNAAVGATAIAFGQYVVDCSLIPHLPRVTFTI 210
C GC A+ DTG S I+G + +E L A+GA YVV C+ P LP ++F +
Sbjct: 173 TLLCEDGCLALVDTGASYISGSTSSIEKLMEALGAKEKRLFDYVVKCNEGPTLPDISFHL 232
Query: 209 AGNDFTLEGNDYVLRVAQFGHTVCLSGFMALDVPKPMGPLWILGDVFIGKYYTEFDAGNR 30
G ++TL DY+ + + +C A+D+P P GP W LG FI K+YTEFD N
Sbjct: 233 GGKEYTLTSADYIFQESYSSKKLCTLAIHAMDIPPPTGPTWALGATFIRKFYTEFDRRNN 292
Query: 29 QLG 21
++G
Sbjct: 293 RIG 295
>M10152-1|AAD03461.1| 406|Homo sapiens renin protein.
Length = 406
Score = 193 bits (471), Expect = 5e-49
Identities = 99/243 (40%), Positives = 139/243 (57%), Gaps = 4/243 (1%)
Frame = -2
Query: 737 DDVTVGGXKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFSTIAVDHVTPVFDNMVAQGLV 558
D +TVGG V Q F E P L F+ A+FDG++GM F A+ VTP+FDN+++QG++
Sbjct: 161 DIITVGGITVT-QMFGEVTEMPALPFMLAEFDGVVGMGFIEQAIGRVTPIFDNIISQGVL 219
Query: 557 -QPVFSFYLNRDP--GATTXXXXXXXGSDPAHYRGDLVRVPLLRDTYWEFHMDSVNVNAS 387
+ VFSFY NRD + GSDP HY G+ + L++ W+ M V+V +S
Sbjct: 220 KEDVFSFYYNRDSENSQSLGGQIVLGGSDPQHYEGNFHYINLIKTGVWQIQMKGVSVGSS 279
Query: 386 RF-CAQGCSAIADTGTSLIAGPSKEVEALNAAVGATAIAFGQYVVDCSLIPHLPRVTFTI 210
C GC A+ DTG S I+G + +E L A+GA F YVV C+ P LP ++F +
Sbjct: 280 TLLCEDGCLALVDTGASYISGSTSSIEKLMEALGAKKRLF-DYVVKCNEGPTLPDISFHL 338
Query: 209 AGNDFTLEGNDYVLRVAQFGHTVCLSGFMALDVPKPMGPLWILGDVFIGKYYTEFDAGNR 30
G ++TL DYV + + +C A+D+P P GP W LG FI K+YTEFD N
Sbjct: 339 GGKEYTLTSADYVFQESYSSKKLCTLAIHAMDIPPPTGPTWALGATFIRKFYTEFDRRNN 398
Query: 29 QLG 21
++G
Sbjct: 399 RIG 401
>L00073-1|AAA60363.1| 406|Homo sapiens renin protein.
Length = 406
Score = 193 bits (471), Expect = 5e-49
Identities = 99/243 (40%), Positives = 139/243 (57%), Gaps = 4/243 (1%)
Frame = -2
Query: 737 DDVTVGGXKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFSTIAVDHVTPVFDNMVAQGLV 558
D +TVGG V Q F E P L F+ A+FDG++GM F A+ VTP+FDN+++QG++
Sbjct: 161 DIITVGGITVT-QMFGEVTEMPALPFMLAEFDGVVGMGFIEQAIGRVTPIFDNIISQGVL 219
Query: 557 -QPVFSFYLNRDP--GATTXXXXXXXGSDPAHYRGDLVRVPLLRDTYWEFHMDSVNVNAS 387
+ VFSFY NRD + GSDP HY G+ + L++ W+ M V+V +S
Sbjct: 220 KEDVFSFYYNRDSENSQSLGGQIVLGGSDPQHYEGNFHYINLIKTGVWQIQMKGVSVGSS 279
Query: 386 RF-CAQGCSAIADTGTSLIAGPSKEVEALNAAVGATAIAFGQYVVDCSLIPHLPRVTFTI 210
C GC A+ DTG S I+G + +E L A+GA F YVV C+ P LP ++F +
Sbjct: 280 TLLCEDGCLALVDTGASYISGSTSSIEKLMEALGAKKRLF-DYVVKCNEGPTLPDISFHL 338
Query: 209 AGNDFTLEGNDYVLRVAQFGHTVCLSGFMALDVPKPMGPLWILGDVFIGKYYTEFDAGNR 30
G ++TL DYV + + +C A+D+P P GP W LG FI K+YTEFD N
Sbjct: 339 GGKEYTLTSADYVFQESYSSKKLCTLAIHAMDIPPPTGPTWALGATFIRKFYTEFDRRNN 398
Query: 29 QLG 21
++G
Sbjct: 399 RIG 401
>CR536498-1|CAG38737.1| 406|Homo sapiens REN protein.
Length = 406
Score = 193 bits (471), Expect = 5e-49
Identities = 99/243 (40%), Positives = 139/243 (57%), Gaps = 4/243 (1%)
Frame = -2
Query: 737 DDVTVGGXKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFSTIAVDHVTPVFDNMVAQGLV 558
D +TVGG V Q F E P L F+ A+FDG++GM F A+ VTP+FDN+++QG++
Sbjct: 161 DIITVGGITVT-QMFGEVTEMPALPFMLAEFDGVVGMGFIEQAIGRVTPIFDNIISQGVL 219
Query: 557 -QPVFSFYLNRDP--GATTXXXXXXXGSDPAHYRGDLVRVPLLRDTYWEFHMDSVNVNAS 387
+ VFSFY NRD + GSDP HY G+ + L++ W+ M V+V +S
Sbjct: 220 KEDVFSFYYNRDSENSQSLGGQIVLGGSDPQHYEGNFHYINLIKTGVWQIQMKGVSVGSS 279
Query: 386 RF-CAQGCSAIADTGTSLIAGPSKEVEALNAAVGATAIAFGQYVVDCSLIPHLPRVTFTI 210
C GC A+ DTG S I+G + +E L A+GA F YVV C+ P LP ++F +
Sbjct: 280 TLLCEDGCLALVDTGASYISGSTSSIEKLMEALGAKKRLF-DYVVKCNEGPTLPDISFHL 338
Query: 209 AGNDFTLEGNDYVLRVAQFGHTVCLSGFMALDVPKPMGPLWILGDVFIGKYYTEFDAGNR 30
G ++TL DYV + + +C A+D+P P GP W LG FI K+YTEFD N
Sbjct: 339 GGKEYTLTSADYVFQESYSSKKLCTLAIHAMDIPPPTGPTWALGATFIRKFYTEFDRRNN 398
Query: 29 QLG 21
++G
Sbjct: 399 RIG 401
>BC047752-1|AAH47752.1| 406|Homo sapiens renin protein.
Length = 406
Score = 193 bits (471), Expect = 5e-49
Identities = 99/243 (40%), Positives = 139/243 (57%), Gaps = 4/243 (1%)
Frame = -2
Query: 737 DDVTVGGXKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFSTIAVDHVTPVFDNMVAQGLV 558
D +TVGG V Q F E P L F+ A+FDG++GM F A+ VTP+FDN+++QG++
Sbjct: 161 DIITVGGITVT-QMFGEVTEMPALPFMLAEFDGVVGMGFIEQAIGRVTPIFDNIISQGVL 219
Query: 557 -QPVFSFYLNRDP--GATTXXXXXXXGSDPAHYRGDLVRVPLLRDTYWEFHMDSVNVNAS 387
+ VFSFY NRD + GSDP HY G+ + L++ W+ M V+V +S
Sbjct: 220 KEDVFSFYYNRDSENSQSLGGQIVLGGSDPQHYEGNFHYINLIKTGVWQIQMKGVSVGSS 279
Query: 386 RF-CAQGCSAIADTGTSLIAGPSKEVEALNAAVGATAIAFGQYVVDCSLIPHLPRVTFTI 210
C GC A+ DTG S I+G + +E L A+GA F YVV C+ P LP ++F +
Sbjct: 280 TLLCEDGCLALVDTGASYISGSTSSIEKLMEALGAKKRLF-DYVVKCNEGPTLPDISFHL 338
Query: 209 AGNDFTLEGNDYVLRVAQFGHTVCLSGFMALDVPKPMGPLWILGDVFIGKYYTEFDAGNR 30
G ++TL DYV + + +C A+D+P P GP W LG FI K+YTEFD N
Sbjct: 339 GGKEYTLTSADYVFQESYSSKKLCTLAIHAMDIPPPTGPTWALGATFIRKFYTEFDRRNN 398
Query: 29 QLG 21
++G
Sbjct: 399 RIG 401
>BC033474-1|AAH33474.1| 406|Homo sapiens renin protein.
Length = 406
Score = 193 bits (471), Expect = 5e-49
Identities = 99/243 (40%), Positives = 139/243 (57%), Gaps = 4/243 (1%)
Frame = -2
Query: 737 DDVTVGGXKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFSTIAVDHVTPVFDNMVAQGLV 558
D +TVGG V Q F E P L F+ A+FDG++GM F A+ VTP+FDN+++QG++
Sbjct: 161 DIITVGGITVT-QMFGEVTEMPALPFMLAEFDGVVGMGFIEQAIGRVTPIFDNIISQGVL 219
Query: 557 -QPVFSFYLNRDP--GATTXXXXXXXGSDPAHYRGDLVRVPLLRDTYWEFHMDSVNVNAS 387
+ VFSFY NRD + GSDP HY G+ + L++ W+ M V+V +S
Sbjct: 220 KEDVFSFYYNRDSENSQSLGGQIVLGGSDPQHYEGNFHYINLIKTGVWQIQMKGVSVGSS 279
Query: 386 RF-CAQGCSAIADTGTSLIAGPSKEVEALNAAVGATAIAFGQYVVDCSLIPHLPRVTFTI 210
C GC A+ DTG S I+G + +E L A+GA F YVV C+ P LP ++F +
Sbjct: 280 TLLCEDGCLALVDTGASYISGSTSSIEKLMEALGAKKRLF-DYVVKCNEGPTLPDISFHL 338
Query: 209 AGNDFTLEGNDYVLRVAQFGHTVCLSGFMALDVPKPMGPLWILGDVFIGKYYTEFDAGNR 30
G ++TL DYV + + +C A+D+P P GP W LG FI K+YTEFD N
Sbjct: 339 GGKEYTLTSADYVFQESYSSKKLCTLAIHAMDIPPPTGPTWALGATFIRKFYTEFDRRNN 398
Query: 29 QLG 21
++G
Sbjct: 399 RIG 401
>AL592146-1|CAI16594.1| 406|Homo sapiens renin protein.
Length = 406
Score = 193 bits (471), Expect = 5e-49
Identities = 99/243 (40%), Positives = 139/243 (57%), Gaps = 4/243 (1%)
Frame = -2
Query: 737 DDVTVGGXKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFSTIAVDHVTPVFDNMVAQGLV 558
D +TVGG V Q F E P L F+ A+FDG++GM F A+ VTP+FDN+++QG++
Sbjct: 161 DIITVGGITVT-QMFGEVTEMPALPFMLAEFDGVVGMGFIEQAIGRVTPIFDNIISQGVL 219
Query: 557 -QPVFSFYLNRDP--GATTXXXXXXXGSDPAHYRGDLVRVPLLRDTYWEFHMDSVNVNAS 387
+ VFSFY NRD + GSDP HY G+ + L++ W+ M V+V +S
Sbjct: 220 KEDVFSFYYNRDSENSQSLGGQIVLGGSDPQHYEGNFHYINLIKTGVWQIQMKGVSVGSS 279
Query: 386 RF-CAQGCSAIADTGTSLIAGPSKEVEALNAAVGATAIAFGQYVVDCSLIPHLPRVTFTI 210
C GC A+ DTG S I+G + +E L A+GA F YVV C+ P LP ++F +
Sbjct: 280 TLLCEDGCLALVDTGASYISGSTSSIEKLMEALGAKKRLF-DYVVKCNEGPTLPDISFHL 338
Query: 209 AGNDFTLEGNDYVLRVAQFGHTVCLSGFMALDVPKPMGPLWILGDVFIGKYYTEFDAGNR 30
G ++TL DYV + + +C A+D+P P GP W LG FI K+YTEFD N
Sbjct: 339 GGKEYTLTSADYVFQESYSSKKLCTLAIHAMDIPPPTGPTWALGATFIRKFYTEFDRRNN 398
Query: 29 QLG 21
++G
Sbjct: 399 RIG 401
>AL592114-1|CAH71224.1| 406|Homo sapiens renin protein.
Length = 406
Score = 193 bits (471), Expect = 5e-49
Identities = 99/243 (40%), Positives = 139/243 (57%), Gaps = 4/243 (1%)
Frame = -2
Query: 737 DDVTVGGXKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFSTIAVDHVTPVFDNMVAQGLV 558
D +TVGG V Q F E P L F+ A+FDG++GM F A+ VTP+FDN+++QG++
Sbjct: 161 DIITVGGITVT-QMFGEVTEMPALPFMLAEFDGVVGMGFIEQAIGRVTPIFDNIISQGVL 219
Query: 557 -QPVFSFYLNRDP--GATTXXXXXXXGSDPAHYRGDLVRVPLLRDTYWEFHMDSVNVNAS 387
+ VFSFY NRD + GSDP HY G+ + L++ W+ M V+V +S
Sbjct: 220 KEDVFSFYYNRDSENSQSLGGQIVLGGSDPQHYEGNFHYINLIKTGVWQIQMKGVSVGSS 279
Query: 386 RF-CAQGCSAIADTGTSLIAGPSKEVEALNAAVGATAIAFGQYVVDCSLIPHLPRVTFTI 210
C GC A+ DTG S I+G + +E L A+GA F YVV C+ P LP ++F +
Sbjct: 280 TLLCEDGCLALVDTGASYISGSTSSIEKLMEALGAKKRLF-DYVVKCNEGPTLPDISFHL 338
Query: 209 AGNDFTLEGNDYVLRVAQFGHTVCLSGFMALDVPKPMGPLWILGDVFIGKYYTEFDAGNR 30
G ++TL DYV + + +C A+D+P P GP W LG FI K+YTEFD N
Sbjct: 339 GGKEYTLTSADYVFQESYSSKKLCTLAIHAMDIPPPTGPTWALGATFIRKFYTEFDRRNN 398
Query: 29 QLG 21
++G
Sbjct: 399 RIG 401
>AY436324-1|AAR03502.1| 403|Homo sapiens renin protein.
Length = 403
Score = 192 bits (469), Expect = 8e-49
Identities = 98/241 (40%), Positives = 139/241 (57%), Gaps = 2/241 (0%)
Frame = -2
Query: 737 DDVTVGGXKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFSTIAVDHVTPVFDNMVAQGLV 558
D +TVGG V Q F E P L F+ A+FDG++GM F A+ VTP+FDN+++QG++
Sbjct: 161 DIITVGGITVT-QMFGEVTEMPALPFMLAEFDGVVGMGFIEQAIGRVTPIFDNIISQGVL 219
Query: 557 -QPVFSFYLNRDPGATTXXXXXXXGSDPAHYRGDLVRVPLLRDTYWEFHMDSVNVNASRF 381
+ VFSFY NR+ + GSDP HY G+ + L++ W+ M V+V +S
Sbjct: 220 KEDVFSFYYNRN-SQSLGGQIVLGGSDPQHYEGNFHYINLIKTGVWQIQMKGVSVGSSTL 278
Query: 380 -CAQGCSAIADTGTSLIAGPSKEVEALNAAVGATAIAFGQYVVDCSLIPHLPRVTFTIAG 204
C GC A+ DTG S I+G + +E L A+GA F YVV C+ P LP ++F + G
Sbjct: 279 LCEDGCLALVDTGASYISGSTSSIEKLMEALGAKKRLF-DYVVKCNEGPTLPDISFHLGG 337
Query: 203 NDFTLEGNDYVLRVAQFGHTVCLSGFMALDVPKPMGPLWILGDVFIGKYYTEFDAGNRQL 24
++TL DYV + + +C A+D+P P GP W LG FI K+YTEFD N ++
Sbjct: 338 KEYTLTSADYVFQESYSSKKLCTLAIHAMDIPPPTGPTWALGATFIRKFYTEFDRRNNRI 397
Query: 23 G 21
G
Sbjct: 398 G 398
>M26901-1|AAA60364.1| 403|Homo sapiens renin protein.
Length = 403
Score = 191 bits (465), Expect = 3e-48
Identities = 98/241 (40%), Positives = 139/241 (57%), Gaps = 2/241 (0%)
Frame = -2
Query: 737 DDVTVGGXKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFSTIAVDHVTPVFDNMVAQGLV 558
D +TVGG V Q F E P L F+ A+FDG++GM F A+ VTP+FDN+++QG++
Sbjct: 161 DIITVGGITVT-QMFGEVTEMPALPFMLAQFDGVVGMGFIEQAIGRVTPIFDNIISQGVL 219
Query: 557 -QPVFSFYLNRDPGATTXXXXXXXGSDPAHYRGDLVRVPLLRDTYWEFHMDSVNVNASRF 381
+ VFSFY NR+ + GSDP HY G+ + L++ W+ M V+V +S
Sbjct: 220 KEDVFSFYYNRN-SQSLGGQIVLGGSDPQHYEGNFHYINLIKTGVWQIQMKGVSVGSSTL 278
Query: 380 -CAQGCSAIADTGTSLIAGPSKEVEALNAAVGATAIAFGQYVVDCSLIPHLPRVTFTIAG 204
C GC A+ DTG S I+G + +E L A+GA F YVV C+ P LP ++F + G
Sbjct: 279 LCEDGCLALVDTGASYISGSTSCIEKLMEALGAKKRLF-DYVVKCNEGPTLPDISFHLGG 337
Query: 203 NDFTLEGNDYVLRVAQFGHTVCLSGFMALDVPKPMGPLWILGDVFIGKYYTEFDAGNRQL 24
++TL DYV + + +C A+D+P P GP W LG FI K+YTEFD N ++
Sbjct: 338 KEYTLTSADYVFQESYSSKKLCTLAIHAMDIPPPTGPTWALGATFIRKFYTEFDRRNNRI 397
Query: 23 G 21
G
Sbjct: 398 G 398
>BC029055-1|AAH29055.1| 388|Homo sapiens pepsinogen 5, group I
(pepsinogen A) protein.
Length = 388
Score = 188 bits (458), Expect = 2e-47
Identities = 100/244 (40%), Positives = 140/244 (57%), Gaps = 2/244 (0%)
Frame = -2
Query: 737 DDVTVGGXKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFSTIAVDHVTPVFDNMVAQGLV 558
D V VGG Q F + +EPG A FDGILG+A+ +I+ TPVFDN+ QGLV
Sbjct: 149 DTVQVGGISDTNQIFGLSETEPGSFLYYAPFDGILGLAYPSISSSGATPVFDNIWNQGLV 208
Query: 557 -QPVFSFYLNRDPGATTXXXXXXXGSDPAHYRGDLVRVPLLRDTYWEFHMDSVNVNASRF 381
Q +FS YL+ D + + D ++Y G L VP+ + YW+ +DS+ +N
Sbjct: 209 SQDLFSVYLSADDKSGSVVIFGGI--DSSYYTGSLNWVPVTVEGYWQITVDSITMNGETI 266
Query: 380 -CAQGCSAIADTGTSLIAGPSKEVEALNAAVGATAIAFGQYVVDCSLIPHLPRVTFTIAG 204
CA+GC AI DTGTSL+ GP+ + + + +GA+ + G VV CS I LP + FTI G
Sbjct: 267 ACAEGCQAIVDTGTSLLTGPTSPIANIQSDIGASENSDGDMVVSCSAISSLPDIVFTING 326
Query: 203 NDFTLEGNDYVLRVAQFGHTVCLSGFMALDVPKPMGPLWILGDVFIGKYYTEFDAGNRQL 24
+ + + Y+L+ C+SGF ++VP G LWILGDVFI +Y+T FD N Q+
Sbjct: 327 VQYPVPPSAYILQ----SEGSCISGFQGMNVPTESGELWILGDVFIRQYFTVFDRANNQV 382
Query: 23 GSRP 12
G P
Sbjct: 383 GLAP 386
>J00287-1|AAA98529.1| 388|Homo sapiens PEP protein.
Length = 388
Score = 187 bits (455), Expect = 4e-47
Identities = 99/244 (40%), Positives = 140/244 (57%), Gaps = 2/244 (0%)
Frame = -2
Query: 737 DDVTVGGXKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFSTIAVDHVTPVFDNMVAQGLV 558
D V VGG Q F + +EPG A FDGILG+A+ +I+ TPVFDN+ QGLV
Sbjct: 149 DTVQVGGISDTNQIFGLSETEPGSFLYYAPFDGILGLAYPSISSSGATPVFDNIWNQGLV 208
Query: 557 -QPVFSFYLNRDPGATTXXXXXXXGSDPAHYRGDLVRVPLLRDTYWEFHMDSVNVNASRF 381
Q +FS YL+ D + + D ++Y G L VP+ + YW+ +DS+ +N
Sbjct: 209 SQDLFSVYLSADDQSGSVVIFGGI--DSSYYTGSLNWVPVTVEGYWQITVDSITMNGEAI 266
Query: 380 -CAQGCSAIADTGTSLIAGPSKEVEALNAAVGATAIAFGQYVVDCSLIPHLPRVTFTIAG 204
CA+GC AI DTGTSL+ GP+ + + + +GA+ + G VV CS I LP + FTI G
Sbjct: 267 ACAEGCQAIVDTGTSLLTGPTSPIANIQSDIGASENSDGDMVVSCSAISSLPDIVFTING 326
Query: 203 NDFTLEGNDYVLRVAQFGHTVCLSGFMALDVPKPMGPLWILGDVFIGKYYTEFDAGNRQL 24
+ + + Y+L+ C+SGF +++P G LWILGDVFI +Y+T FD N Q+
Sbjct: 327 VQYPVPPSAYILQ----SEGSCISGFQGMNLPTESGELWILGDVFIRQYFTVFDRANNQV 382
Query: 23 GSRP 12
G P
Sbjct: 383 GLAP 386
>M26032-1|AAA60061.1| 388|Homo sapiens pepsinogen A protein.
Length = 388
Score = 185 bits (451), Expect = 1e-46
Identities = 98/244 (40%), Positives = 140/244 (57%), Gaps = 2/244 (0%)
Frame = -2
Query: 737 DDVTVGGXKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFSTIAVDHVTPVFDNMVAQGLV 558
D V VGG Q F + +EPG A FDGILG+A+ +I+ TPVFDN+ QGLV
Sbjct: 149 DTVQVGGISDTNQIFGLSETEPGSFLYYAPFDGILGLAYPSISSSGATPVFDNIWNQGLV 208
Query: 557 -QPVFSFYLNRDPGATTXXXXXXXGSDPAHYRGDLVRVPLLRDTYWEFHMDSVNVNASRF 381
Q +FS YL+ D + + D ++Y G L VP+ + YW+ +DS+ +N
Sbjct: 209 SQDLFSVYLSADDQSGSVVIFGGI--DSSYYTGSLNWVPVTVEGYWQITVDSITMNGEAI 266
Query: 380 -CAQGCSAIADTGTSLIAGPSKEVEALNAAVGATAIAFGQYVVDCSLIPHLPRVTFTIAG 204
CA+GC AI DTGTSL+ GP+ + + + +GA+ + G VV CS I LP + FTI G
Sbjct: 267 ACAEGCQAIVDTGTSLLTGPTSPIANIQSDIGASENSDGDMVVSCSAISSLPDIVFTING 326
Query: 203 NDFTLEGNDYVLRVAQFGHTVCLSGFMALDVPKPMGPLWILGDVFIGKYYTEFDAGNRQL 24
+ + + Y+L+ C+SGF +++P G LWILGDVFI +Y+T F+ N Q+
Sbjct: 327 VQYPVPPSAYILQ----SEGSCISGFQGMNLPTESGELWILGDVFIRQYFTVFERANNQV 382
Query: 23 GSRP 12
G P
Sbjct: 383 GLAP 386
>U75272-1|AAB18273.1| 388|Homo sapiens gastricsin protein.
Length = 388
Score = 167 bits (406), Expect = 4e-41
Identities = 90/243 (37%), Positives = 136/243 (55%), Gaps = 4/243 (1%)
Frame = -2
Query: 737 DDVTVGGXKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFSTIAVDHVTPVFDNMVAQG-L 561
D +TV +V Q F + +EPG FV A+FDGI+G+A+ ++VD T MV +G L
Sbjct: 146 DTLTVQSIQVPNQEFGLSENEPGTNFVYAQFDGIMGLAYPALSVDEATTAMQGMVQEGAL 205
Query: 560 VQPVFSFYLNRDPGATTXXXXXXXGSDPAHYRGDLVRVPLLRDTYWEFHMDS--VNVNAS 387
PVFS YL+ G++ D + Y G + P+ ++ YW+ ++ + AS
Sbjct: 206 TSPVFSVYLSNQQGSSGGAVVFGGV-DSSLYTGQIYWAPVTQELYWQIGIEEFLIGGQAS 264
Query: 386 RFCAQGCSAIADTGTSLIAGPSKEVEALNAAVGATAIAFGQYVVDCSLIPHLPRVTFTIA 207
+C++GC AI DTGTSL+ P + + AL A GA +GQ++V+C+ I +LP +TF I
Sbjct: 265 GWCSEGCQAIVDTGTSLLTVPQQYMSALLQATGAQEDEYGQFLVNCNSIQNLPSLTFIIN 324
Query: 206 GNDFTLEGNDYVLRVAQFGHTVCLSGFMALDVPKPMG-PLWILGDVFIGKYYTEFDAGNR 30
G +F L + Y+L + C G + G PLWILGDVF+ YY+ +D GN
Sbjct: 325 GVEFPLPPSSYILS----NNGYCTVGVEPTYLSSQNGQPLWILGDVFLRSYYSVYDLGNN 380
Query: 29 QLG 21
++G
Sbjct: 381 RVG 383
>M23077-1|AAA60063.1| 388|Homo sapiens pepsinogen C protein.
Length = 388
Score = 167 bits (406), Expect = 4e-41
Identities = 90/243 (37%), Positives = 136/243 (55%), Gaps = 4/243 (1%)
Frame = -2
Query: 737 DDVTVGGXKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFSTIAVDHVTPVFDNMVAQG-L 561
D +TV +V Q F + +EPG FV A+FDGI+G+A+ ++VD T MV +G L
Sbjct: 146 DTLTVQSIQVPNQEFGLSENEPGTNFVYAQFDGIMGLAYPALSVDEATTAMQGMVQEGAL 205
Query: 560 VQPVFSFYLNRDPGATTXXXXXXXGSDPAHYRGDLVRVPLLRDTYWEFHMDS--VNVNAS 387
PVFS YL+ G++ D + Y G + P+ ++ YW+ ++ + AS
Sbjct: 206 TSPVFSVYLSNQQGSSGGAVVFGGV-DSSLYTGQIYWAPVTQELYWQIGIEEFLIGGQAS 264
Query: 386 RFCAQGCSAIADTGTSLIAGPSKEVEALNAAVGATAIAFGQYVVDCSLIPHLPRVTFTIA 207
+C++GC AI DTGTSL+ P + + AL A GA +GQ++V+C+ I +LP +TF I
Sbjct: 265 GWCSEGCQAIVDTGTSLLTVPQQYMSALLQATGAQEDEYGQFLVNCNSIQNLPSLTFIIN 324
Query: 206 GNDFTLEGNDYVLRVAQFGHTVCLSGFMALDVPKPMG-PLWILGDVFIGKYYTEFDAGNR 30
G +F L + Y+L + C G + G PLWILGDVF+ YY+ +D GN
Sbjct: 325 GVEFPLPPSSYILS----NNGYCTVGVEPTYLSSQNGQPLWILGDVFLRSYYSVYDLGNN 380
Query: 29 QLG 21
++G
Sbjct: 381 RVG 383
>M18667-1|AAA60062.1| 385|Homo sapiens pepsinogen protein.
Length = 385
Score = 167 bits (406), Expect = 4e-41
Identities = 90/243 (37%), Positives = 136/243 (55%), Gaps = 4/243 (1%)
Frame = -2
Query: 737 DDVTVGGXKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFSTIAVDHVTPVFDNMVAQG-L 561
D +TV +V Q F + +EPG FV A+FDGI+G+A+ ++VD T MV +G L
Sbjct: 143 DTLTVQSIQVPNQEFGLSENEPGTNFVYAQFDGIMGLAYPALSVDEATTAMQGMVQEGAL 202
Query: 560 VQPVFSFYLNRDPGATTXXXXXXXGSDPAHYRGDLVRVPLLRDTYWEFHMDS--VNVNAS 387
PVFS YL+ G++ D + Y G + P+ ++ YW+ ++ + AS
Sbjct: 203 TSPVFSVYLSNQQGSSGGAVVFGGV-DSSLYTGQIYWAPVTQELYWQIGIEEFLIGGQAS 261
Query: 386 RFCAQGCSAIADTGTSLIAGPSKEVEALNAAVGATAIAFGQYVVDCSLIPHLPRVTFTIA 207
+C++GC AI DTGTSL+ P + + AL A GA +GQ++V+C+ I +LP +TF I
Sbjct: 262 GWCSEGCQAIVDTGTSLLTVPQQYMSALLQATGAQEDEYGQFLVNCNSIQNLPSLTFIIN 321
Query: 206 GNDFTLEGNDYVLRVAQFGHTVCLSGFMALDVPKPMG-PLWILGDVFIGKYYTEFDAGNR 30
G +F L + Y+L + C G + G PLWILGDVF+ YY+ +D GN
Sbjct: 322 GVEFPLPPSSYILS----NNGYCTVGVEPTYLSSQNGQPLWILGDVFLRSYYSVYDLGNN 377
Query: 29 QLG 21
++G
Sbjct: 378 RVG 380
>J04443-1|AAA60074.1| 388|Homo sapiens pepsinogen protein.
Length = 388
Score = 167 bits (406), Expect = 4e-41
Identities = 90/243 (37%), Positives = 136/243 (55%), Gaps = 4/243 (1%)
Frame = -2
Query: 737 DDVTVGGXKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFSTIAVDHVTPVFDNMVAQG-L 561
D +TV +V Q F + +EPG FV A+FDGI+G+A+ ++VD T MV +G L
Sbjct: 146 DTLTVQSIQVPNQEFGLSENEPGTNFVYAQFDGIMGLAYPALSVDEATTAMQGMVQEGAL 205
Query: 560 VQPVFSFYLNRDPGATTXXXXXXXGSDPAHYRGDLVRVPLLRDTYWEFHMDS--VNVNAS 387
PVFS YL+ G++ D + Y G + P+ ++ YW+ ++ + AS
Sbjct: 206 TSPVFSVYLSNQQGSSGGAVVFGGV-DSSLYTGQIYWAPVTQELYWQIGIEEFLIGGQAS 264
Query: 386 RFCAQGCSAIADTGTSLIAGPSKEVEALNAAVGATAIAFGQYVVDCSLIPHLPRVTFTIA 207
+C++GC AI DTGTSL+ P + + AL A GA +GQ++V+C+ I +LP +TF I
Sbjct: 265 GWCSEGCQAIVDTGTSLLTVPQQYMSALLQATGAQEDEYGQFLVNCNSIQNLPSLTFIIN 324
Query: 206 GNDFTLEGNDYVLRVAQFGHTVCLSGFMALDVPKPMG-PLWILGDVFIGKYYTEFDAGNR 30
G +F L + Y+L + C G + G PLWILGDVF+ YY+ +D GN
Sbjct: 325 GVEFPLPPSSYILS----NNGYCTVGVEPTYLSSQNGQPLWILGDVFLRSYYSVYDLGNN 380
Query: 29 QLG 21
++G
Sbjct: 381 RVG 383
>BC073740-1|AAH73740.1| 388|Homo sapiens progastricsin (pepsinogen
C) protein.
Length = 388
Score = 167 bits (406), Expect = 4e-41
Identities = 90/243 (37%), Positives = 136/243 (55%), Gaps = 4/243 (1%)
Frame = -2
Query: 737 DDVTVGGXKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFSTIAVDHVTPVFDNMVAQG-L 561
D +TV +V Q F + +EPG FV A+FDGI+G+A+ ++VD T MV +G L
Sbjct: 146 DTLTVQSIQVPNQEFGLSENEPGTNFVYAQFDGIMGLAYPALSVDEATTAMQGMVQEGAL 205
Query: 560 VQPVFSFYLNRDPGATTXXXXXXXGSDPAHYRGDLVRVPLLRDTYWEFHMDS--VNVNAS 387
PVFS YL+ G++ D + Y G + P+ ++ YW+ ++ + AS
Sbjct: 206 TSPVFSVYLSNQQGSSGGAVVFGGV-DSSLYTGQIYWAPVTQELYWQIGIEEFLIGGQAS 264
Query: 386 RFCAQGCSAIADTGTSLIAGPSKEVEALNAAVGATAIAFGQYVVDCSLIPHLPRVTFTIA 207
+C++GC AI DTGTSL+ P + + AL A GA +GQ++V+C+ I +LP +TF I
Sbjct: 265 GWCSEGCQAIVDTGTSLLTVPQQYMSALLQATGAQEDEYGQFLVNCNSIQNLPSLTFIIN 324
Query: 206 GNDFTLEGNDYVLRVAQFGHTVCLSGFMALDVPKPMG-PLWILGDVFIGKYYTEFDAGNR 30
G +F L + Y+L + C G + G PLWILGDVF+ YY+ +D GN
Sbjct: 325 GVEFPLPPSSYILS----NNGYCTVGVEPTYLSSQNGQPLWILGDVFLRSYYSVYDLGNN 380
Query: 29 QLG 21
++G
Sbjct: 381 RVG 383
>AL365205-1|CAI13181.1| 388|Homo sapiens progastricsin (pepsinogen
C) protein.
Length = 388
Score = 167 bits (406), Expect = 4e-41
Identities = 90/243 (37%), Positives = 136/243 (55%), Gaps = 4/243 (1%)
Frame = -2
Query: 737 DDVTVGGXKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFSTIAVDHVTPVFDNMVAQG-L 561
D +TV +V Q F + +EPG FV A+FDGI+G+A+ ++VD T MV +G L
Sbjct: 146 DTLTVQSIQVPNQEFGLSENEPGTNFVYAQFDGIMGLAYPALSVDEATTAMQGMVQEGAL 205
Query: 560 VQPVFSFYLNRDPGATTXXXXXXXGSDPAHYRGDLVRVPLLRDTYWEFHMDS--VNVNAS 387
PVFS YL+ G++ D + Y G + P+ ++ YW+ ++ + AS
Sbjct: 206 TSPVFSVYLSNQQGSSGGAVVFGGV-DSSLYTGQIYWAPVTQELYWQIGIEEFLIGGQAS 264
Query: 386 RFCAQGCSAIADTGTSLIAGPSKEVEALNAAVGATAIAFGQYVVDCSLIPHLPRVTFTIA 207
+C++GC AI DTGTSL+ P + + AL A GA +GQ++V+C+ I +LP +TF I
Sbjct: 265 GWCSEGCQAIVDTGTSLLTVPQQYMSALLQATGAQEDEYGQFLVNCNSIQNLPSLTFIIN 324
Query: 206 GNDFTLEGNDYVLRVAQFGHTVCLSGFMALDVPKPMG-PLWILGDVFIGKYYTEFDAGNR 30
G +F L + Y+L + C G + G PLWILGDVF+ YY+ +D GN
Sbjct: 325 GVEFPLPPSSYILS----NNGYCTVGVEPTYLSSQNGQPLWILGDVFLRSYYSVYDLGNN 380
Query: 29 QLG 21
++G
Sbjct: 381 RVG 383
>BX571818-5|CAH73265.1| 363|Homo sapiens cathepsin E protein.
Length = 363
Score = 101 bits (241), Expect = 4e-21
Identities = 50/113 (44%), Positives = 71/113 (62%), Gaps = 1/113 (0%)
Frame = -2
Query: 737 DDVTVGGXKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFSTIAVDHVTPVFDNMVAQGLV 558
D V+V G V Q F E+V+EPG FV A+FDGILG+ + ++AV VTPVFDNM+AQ LV
Sbjct: 151 DQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGILGLGYPSLAVGGVTPVFDNMMAQNLV 210
Query: 557 Q-PVFSFYLNRDPGATTXXXXXXXGSDPAHYRGDLVRVPLLRDTYWEFHMDSV 402
P+FS Y++ +P G D +H+ G L VP+ + YW+ +D++
Sbjct: 211 DLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSLNWVPVTKQAYWQIALDNM 263
>AJ250716-1|CAB82849.1| 363|Homo sapiens cathepsin E, alternative
protein.
Length = 363
Score = 101 bits (241), Expect = 4e-21
Identities = 50/113 (44%), Positives = 71/113 (62%), Gaps = 1/113 (0%)
Frame = -2
Query: 737 DDVTVGGXKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFSTIAVDHVTPVFDNMVAQGLV 558
D V+V G V Q F E+V+EPG FV A+FDGILG+ + ++AV VTPVFDNM+AQ LV
Sbjct: 151 DQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGILGLGYPSLAVGGVTPVFDNMMAQNLV 210
Query: 557 Q-PVFSFYLNRDPGATTXXXXXXXGSDPAHYRGDLVRVPLLRDTYWEFHMDSV 402
P+FS Y++ +P G D +H+ G L VP+ + YW+ +D++
Sbjct: 211 DLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSLNWVPVTKQAYWQIALDNM 263
>AL365205-2|CAI95135.1| 140|Homo sapiens progastricsin (pepsinogen
C) protein.
Length = 140
Score = 60.5 bits (140), Expect = 6e-09
Identities = 30/70 (42%), Positives = 41/70 (58%), Gaps = 1/70 (1%)
Frame = -2
Query: 725 VGGXKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFSTIAVDHVTPVFDNMVAQG-LVQPV 549
V +V Q F + +EPG FV A+FDGI+G+A+ ++VD T MV +G L PV
Sbjct: 71 VQSIQVPNQEFGLSENEPGTNFVYAQFDGIMGLAYPALSVDEATTAMQGMVQEGALTSPV 130
Query: 548 FSFYLNRDPG 519
FS YL+ G
Sbjct: 131 FSVYLSNQQG 140
>AF188276-1|AAF35835.1| 468|Homo sapiens aspartyl protease protein.
Length = 468
Score = 50.4 bits (115), Expect = 7e-06
Identities = 40/150 (26%), Positives = 73/150 (48%), Gaps = 14/150 (9%)
Frame = -2
Query: 650 KFDGILGMAFSTIAV--DHVTPVFDNMVAQGLVQPVFSFY-----LNRDPGATTXXXXXX 492
K++GILG+A++T+A + FD++V Q + VFS L T
Sbjct: 192 KWNGILGLAYATLAKPSSSLETFFDSLVTQANIPNVFSMQMCGAGLPVAGSGTNGGSLVL 251
Query: 491 XGSDPAHYRGDLVRVPLLRDTYWEFHM-------DSVNVNASRFCAQGCSAIADTGTSLI 333
G +P+ Y+GD+ P+ + Y++ + S+N++ + A AI D+GT+L+
Sbjct: 252 GGIEPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNAD--KAIVDSGTTLL 309
Query: 332 AGPSKEVEALNAAVGATAIAFGQYVVDCSL 243
P K +A+ AV ++ + Q ++ L
Sbjct: 310 RLPQKVFDAVVEAVARASLLYIQPMMGAGL 339
>AK075539-1|BAC11682.1| 423|Homo sapiens protein ( Homo sapiens
cDNA PSEC0239 fis, clone OVARC1000363, highly similar to
Homo sapiens aspartyl protease mRNA. ).
Length = 423
Score = 48.8 bits (111), Expect = 2e-05
Identities = 41/152 (26%), Positives = 75/152 (49%), Gaps = 16/152 (10%)
Frame = -2
Query: 683 VSEPGLAFVAA-KFDGILGMAFSTIAV--DHVTPVFDNMVAQGLVQPVFSFYLNRDPGAT 513
+ E G F+ +++GILG+A++T+A + FD++V Q + VFS + R G
Sbjct: 85 IFESGNFFLPGIQWNGILGLAYATLAKPSSSLETFFDSLVTQANIPNVFSMQM-RGAGLP 143
Query: 512 TXXXXXXXGS------DPAHYRGDLVRVPLLRDTYWEFHM-------DSVNVNASRFCAQ 372
GS +P+ Y+GD+ P+ + Y++ + S+N++ + A
Sbjct: 144 VAGSGTNGGSLVLGGIEPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNAD 203
Query: 371 GCSAIADTGTSLIAGPSKEVEALNAAVGATAI 276
AI D+GT+L+ P K +A+ AV ++
Sbjct: 204 --KAIVDSGTTLLRLPQKVFDAVVEAVARASL 233
>BC014453-1|AAH14453.1| 518|Homo sapiens beta-site APP-cleaving
enzyme 2 protein.
Length = 518
Score = 48.4 bits (110), Expect = 3e-05
Identities = 38/139 (27%), Positives = 68/139 (48%), Gaps = 14/139 (10%)
Frame = -2
Query: 650 KFDGILGMAFSTIAV--DHVTPVFDNMVAQGLVQPVFSFY-----LNRDPGATTXXXXXX 492
K++GILG+A++T+A + FD++V Q + VFS L T
Sbjct: 192 KWNGILGLAYATLAKPSSSLETFFDSLVTQANIPNVFSMQMCGAGLPVAGSGTNGGSLVL 251
Query: 491 XGSDPAHYRGDLVRVPLLRDTYWEFHM-------DSVNVNASRFCAQGCSAIADTGTSLI 333
G +P+ Y+GD+ P+ + Y++ + S+N++ + A AI D+GT+L+
Sbjct: 252 GGIEPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNAD--KAIVDSGTTLL 309
Query: 332 AGPSKEVEALNAAVGATAI 276
P K +A+ AV ++
Sbjct: 310 RLPQKVFDAVVEAVARASL 328
>AY358927-1|AAQ89286.1| 518|Homo sapiens BACE2 protein.
Length = 518
Score = 48.4 bits (110), Expect = 3e-05
Identities = 38/139 (27%), Positives = 68/139 (48%), Gaps = 14/139 (10%)
Frame = -2
Query: 650 KFDGILGMAFSTIAV--DHVTPVFDNMVAQGLVQPVFSFY-----LNRDPGATTXXXXXX 492
K++GILG+A++T+A + FD++V Q + VFS L T
Sbjct: 192 KWNGILGLAYATLAKPSSSLETFFDSLVTQANIPNVFSMQMCGAGLPVAGSGTNGGSLVL 251
Query: 491 XGSDPAHYRGDLVRVPLLRDTYWEFHM-------DSVNVNASRFCAQGCSAIADTGTSLI 333
G +P+ Y+GD+ P+ + Y++ + S+N++ + A AI D+GT+L+
Sbjct: 252 GGIEPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNAD--KAIVDSGTTLL 309
Query: 332 AGPSKEVEALNAAVGATAI 276
P K +A+ AV ++
Sbjct: 310 RLPQKVFDAVVEAVARASL 328
>AL163285-1|CAB90554.1| 415|Homo sapiens beta-site APP-cleaving
enzyme 2, EC 3.4.23. protein.
Length = 415
Score = 48.4 bits (110), Expect = 3e-05
Identities = 38/139 (27%), Positives = 68/139 (48%), Gaps = 14/139 (10%)
Frame = -2
Query: 650 KFDGILGMAFSTIAV--DHVTPVFDNMVAQGLVQPVFSFY-----LNRDPGATTXXXXXX 492
K++GILG+A++T+A + FD++V Q + VFS L T
Sbjct: 89 KWNGILGLAYATLAKPSSSLETFFDSLVTQANIPNVFSMQMCGAGLPVAGSGTNGGSLVL 148
Query: 491 XGSDPAHYRGDLVRVPLLRDTYWEFHM-------DSVNVNASRFCAQGCSAIADTGTSLI 333
G +P+ Y+GD+ P+ + Y++ + S+N++ + A AI D+GT+L+
Sbjct: 149 GGIEPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNAD--KAIVDSGTTLL 206
Query: 332 AGPSKEVEALNAAVGATAI 276
P K +A+ AV ++
Sbjct: 207 RLPQKVFDAVVEAVARASL 225
>AF212252-1|AAG41783.1| 439|Homo sapiens CDA13 protein.
Length = 439
Score = 48.4 bits (110), Expect = 3e-05
Identities = 38/139 (27%), Positives = 68/139 (48%), Gaps = 14/139 (10%)
Frame = -2
Query: 650 KFDGILGMAFSTIAV--DHVTPVFDNMVAQGLVQPVFSFY-----LNRDPGATTXXXXXX 492
K++GILG+A++T+A + FD++V Q + VFS L T
Sbjct: 113 KWNGILGLAYATLAKPSSSLETFFDSLVTQANIPNVFSMQMCGAGLPVAGSGTNGGSLVL 172
Query: 491 XGSDPAHYRGDLVRVPLLRDTYWEFHM-------DSVNVNASRFCAQGCSAIADTGTSLI 333
G +P+ Y+GD+ P+ + Y++ + S+N++ + A AI D+GT+L+
Sbjct: 173 GGIEPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNAD--KAIVDSGTTLL 230
Query: 332 AGPSKEVEALNAAVGATAI 276
P K +A+ AV ++
Sbjct: 231 RLPQKVFDAVVEAVARASL 249
>AF204944-1|AAF26368.1| 518|Homo sapiens transmembrane aspartic
proteinase Asp 1 protein.
Length = 518
Score = 48.4 bits (110), Expect = 3e-05
Identities = 38/139 (27%), Positives = 68/139 (48%), Gaps = 14/139 (10%)
Frame = -2
Query: 650 KFDGILGMAFSTIAV--DHVTPVFDNMVAQGLVQPVFSFY-----LNRDPGATTXXXXXX 492
K++GILG+A++T+A + FD++V Q + VFS L T
Sbjct: 192 KWNGILGLAYATLAKPSSSLETFFDSLVTQANIPNVFSMQMCGAGLPVAGSGTNGGSLVL 251
Query: 491 XGSDPAHYRGDLVRVPLLRDTYWEFHM-------DSVNVNASRFCAQGCSAIADTGTSLI 333
G +P+ Y+GD+ P+ + Y++ + S+N++ + A AI D+GT+L+
Sbjct: 252 GGIEPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNAD--KAIVDSGTTLL 309
Query: 332 AGPSKEVEALNAAVGATAI 276
P K +A+ AV ++
Sbjct: 310 RLPQKVFDAVVEAVARASL 328
>AF200342-1|AAF17078.1| 518|Homo sapiens aspartyl protease 1
protein.
Length = 518
Score = 48.4 bits (110), Expect = 3e-05
Identities = 38/139 (27%), Positives = 68/139 (48%), Gaps = 14/139 (10%)
Frame = -2
Query: 650 KFDGILGMAFSTIAV--DHVTPVFDNMVAQGLVQPVFSFY-----LNRDPGATTXXXXXX 492
K++GILG+A++T+A + FD++V Q + VFS L T
Sbjct: 192 KWNGILGLAYATLAKPSSSLETFFDSLVTQANIPNVFSMQMCGAGLPVAGSGTNGGSLVL 251
Query: 491 XGSDPAHYRGDLVRVPLLRDTYWEFHM-------DSVNVNASRFCAQGCSAIADTGTSLI 333
G +P+ Y+GD+ P+ + Y++ + S+N++ + A AI D+GT+L+
Sbjct: 252 GGIEPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNAD--KAIVDSGTTLL 309
Query: 332 AGPSKEVEALNAAVGATAI 276
P K +A+ AV ++
Sbjct: 310 RLPQKVFDAVVEAVARASL 328
>AF200192-1|AAF13714.1| 518|Homo sapiens memapsin 1 protein.
Length = 518
Score = 48.4 bits (110), Expect = 3e-05
Identities = 38/139 (27%), Positives = 68/139 (48%), Gaps = 14/139 (10%)
Frame = -2
Query: 650 KFDGILGMAFSTIAV--DHVTPVFDNMVAQGLVQPVFSFY-----LNRDPGATTXXXXXX 492
K++GILG+A++T+A + FD++V Q + VFS L T
Sbjct: 192 KWNGILGLAYATLAKPSSSLETFFDSLVTQANIPNVFSMQMCGAGLPVAGSGTNGGSLVL 251
Query: 491 XGSDPAHYRGDLVRVPLLRDTYWEFHM-------DSVNVNASRFCAQGCSAIADTGTSLI 333
G +P+ Y+GD+ P+ + Y++ + S+N++ + A AI D+GT+L+
Sbjct: 252 GGIEPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNAD--KAIVDSGTTLL 309
Query: 332 AGPSKEVEALNAAVGATAI 276
P K +A+ AV ++
Sbjct: 310 RLPQKVFDAVVEAVARASL 328
>AF188277-1|AAF35836.1| 396|Homo sapiens aspartyl protease protein.
Length = 396
Score = 48.4 bits (110), Expect = 3e-05
Identities = 38/139 (27%), Positives = 68/139 (48%), Gaps = 14/139 (10%)
Frame = -2
Query: 650 KFDGILGMAFSTIAV--DHVTPVFDNMVAQGLVQPVFSFY-----LNRDPGATTXXXXXX 492
K++GILG+A++T+A + FD++V Q + VFS L T
Sbjct: 192 KWNGILGLAYATLAKPSSSLETFFDSLVTQANIPNVFSMQMCGAGLPVAGSGTNGGSLVL 251
Query: 491 XGSDPAHYRGDLVRVPLLRDTYWEFHM-------DSVNVNASRFCAQGCSAIADTGTSLI 333
G +P+ Y+GD+ P+ + Y++ + S+N++ + A AI D+GT+L+
Sbjct: 252 GGIEPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNAD--KAIVDSGTTLL 309
Query: 332 AGPSKEVEALNAAVGATAI 276
P K +A+ AV ++
Sbjct: 310 RLPQKVFDAVVEAVARASL 328
>AF178532-1|AAF29494.1| 518|Homo sapiens aspartyl protease protein.
Length = 518
Score = 48.4 bits (110), Expect = 3e-05
Identities = 38/139 (27%), Positives = 68/139 (48%), Gaps = 14/139 (10%)
Frame = -2
Query: 650 KFDGILGMAFSTIAV--DHVTPVFDNMVAQGLVQPVFSFY-----LNRDPGATTXXXXXX 492
K++GILG+A++T+A + FD++V Q + VFS L T
Sbjct: 192 KWNGILGLAYATLAKPSSSLETFFDSLVTQANIPNVFSMQMCGAGLPVAGSGTNGGSLVL 251
Query: 491 XGSDPAHYRGDLVRVPLLRDTYWEFHM-------DSVNVNASRFCAQGCSAIADTGTSLI 333
G +P+ Y+GD+ P+ + Y++ + S+N++ + A AI D+GT+L+
Sbjct: 252 GGIEPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNAD--KAIVDSGTTLL 309
Query: 332 AGPSKEVEALNAAVGATAI 276
P K +A+ AV ++
Sbjct: 310 RLPQKVFDAVVEAVARASL 328
>AF117892-1|AAD45240.1| 518|Homo sapiens aspartic-like protease
protein.
Length = 518
Score = 48.4 bits (110), Expect = 3e-05
Identities = 38/139 (27%), Positives = 68/139 (48%), Gaps = 14/139 (10%)
Frame = -2
Query: 650 KFDGILGMAFSTIAV--DHVTPVFDNMVAQGLVQPVFSFY-----LNRDPGATTXXXXXX 492
K++GILG+A++T+A + FD++V Q + VFS L T
Sbjct: 192 KWNGILGLAYATLAKPSSSLETFFDSLVTQANIPNVFSMQMCGAGLPVAGSGTNGGSLVL 251
Query: 491 XGSDPAHYRGDLVRVPLLRDTYWEFHM-------DSVNVNASRFCAQGCSAIADTGTSLI 333
G +P+ Y+GD+ P+ + Y++ + S+N++ + A AI D+GT+L+
Sbjct: 252 GGIEPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNAD--KAIVDSGTTLL 309
Query: 332 AGPSKEVEALNAAVGATAI 276
P K +A+ AV ++
Sbjct: 310 RLPQKVFDAVVEAVARASL 328
>AF050171-1|AAD45963.1| 518|Homo sapiens aspartyl protease protein.
Length = 518
Score = 48.4 bits (110), Expect = 3e-05
Identities = 38/139 (27%), Positives = 68/139 (48%), Gaps = 14/139 (10%)
Frame = -2
Query: 650 KFDGILGMAFSTIAV--DHVTPVFDNMVAQGLVQPVFSFY-----LNRDPGATTXXXXXX 492
K++GILG+A++T+A + FD++V Q + VFS L T
Sbjct: 192 KWNGILGLAYATLAKPSSSLETFFDSLVTQANIPNVFSMQMCGAGLPVAGSGTNGGSLVL 251
Query: 491 XGSDPAHYRGDLVRVPLLRDTYWEFHM-------DSVNVNASRFCAQGCSAIADTGTSLI 333
G +P+ Y+GD+ P+ + Y++ + S+N++ + A AI D+GT+L+
Sbjct: 252 GGIEPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNAD--KAIVDSGTTLL 309
Query: 332 AGPSKEVEALNAAVGATAI 276
P K +A+ AV ++
Sbjct: 310 RLPQKVFDAVVEAVARASL 328
>DQ007053-1|AAY16982.1| 501|Homo sapiens beta-site APP-cleaving
enzyme 1 protein.
Length = 501
Score = 44.4 bits (100), Expect = 4e-04
Identities = 44/152 (28%), Positives = 73/152 (48%), Gaps = 16/152 (10%)
Frame = -2
Query: 686 AVSEPGLAFV-AAKFDGILGMAFSTIAV--DHVTPVFDNMVAQGLVQPVFS-------FY 537
A++E F+ + ++GILG+A++ IA D + P FD++V Q V +FS F
Sbjct: 162 AITESDKFFINGSNWEGILGLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFP 221
Query: 536 LNRDPG-ATTXXXXXXXGSDPAHYRGDLVRVPLLRDTYWEFHMDSVNVNASRF---CAQ- 372
LN+ A+ G D + Y G L P+ R+ Y+E + V +N C +
Sbjct: 222 LNQSEVLASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEY 281
Query: 371 -GCSAIADTGTSLIAGPSKEVEALNAAVGATA 279
+I D+GT+ + P K EA ++ A +
Sbjct: 282 NYDKSIVDSGTTNLRLPKKVFEAAVKSIKAAS 313
>BC065492-1|AAH65492.1| 501|Homo sapiens beta-site APP-cleaving
enzyme 1 protein.
Length = 501
Score = 44.4 bits (100), Expect = 4e-04
Identities = 44/152 (28%), Positives = 73/152 (48%), Gaps = 16/152 (10%)
Frame = -2
Query: 686 AVSEPGLAFV-AAKFDGILGMAFSTIAV--DHVTPVFDNMVAQGLVQPVFS-------FY 537
A++E F+ + ++GILG+A++ IA D + P FD++V Q V +FS F
Sbjct: 162 AITESDKFFINGSNWEGILGLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFP 221
Query: 536 LNRDPG-ATTXXXXXXXGSDPAHYRGDLVRVPLLRDTYWEFHMDSVNVNASRF---CAQ- 372
LN+ A+ G D + Y G L P+ R+ Y+E + V +N C +
Sbjct: 222 LNQSEVLASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEY 281
Query: 371 -GCSAIADTGTSLIAGPSKEVEALNAAVGATA 279
+I D+GT+ + P K EA ++ A +
Sbjct: 282 NYDKSIVDSGTTNLRLPKKVFEAAVKSIKAAS 313
>BC036084-1|AAH36084.1| 501|Homo sapiens beta-site APP-cleaving
enzyme 1 protein.
Length = 501
Score = 44.4 bits (100), Expect = 4e-04
Identities = 44/152 (28%), Positives = 73/152 (48%), Gaps = 16/152 (10%)
Frame = -2
Query: 686 AVSEPGLAFV-AAKFDGILGMAFSTIAV--DHVTPVFDNMVAQGLVQPVFS-------FY 537
A++E F+ + ++GILG+A++ IA D + P FD++V Q V +FS F
Sbjct: 162 AITESDKFFINGSNWEGILGLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFP 221
Query: 536 LNRDPG-ATTXXXXXXXGSDPAHYRGDLVRVPLLRDTYWEFHMDSVNVNASRF---CAQ- 372
LN+ A+ G D + Y G L P+ R+ Y+E + V +N C +
Sbjct: 222 LNQSEVLASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEY 281
Query: 371 -GCSAIADTGTSLIAGPSKEVEALNAAVGATA 279
+I D+GT+ + P K EA ++ A +
Sbjct: 282 NYDKSIVDSGTTNLRLPKKVFEAAVKSIKAAS 313
>AF204943-1|AAF26367.1| 501|Homo sapiens transmembrane aspartic
proteinase Asp 2 protein.
Length = 501
Score = 44.4 bits (100), Expect = 4e-04
Identities = 44/152 (28%), Positives = 73/152 (48%), Gaps = 16/152 (10%)
Frame = -2
Query: 686 AVSEPGLAFV-AAKFDGILGMAFSTIAV--DHVTPVFDNMVAQGLVQPVFS-------FY 537
A++E F+ + ++GILG+A++ IA D + P FD++V Q V +FS F
Sbjct: 162 AITESDKFFINGSNWEGILGLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFP 221
Query: 536 LNRDPG-ATTXXXXXXXGSDPAHYRGDLVRVPLLRDTYWEFHMDSVNVNASRF---CAQ- 372
LN+ A+ G D + Y G L P+ R+ Y+E + V +N C +
Sbjct: 222 LNQSEVLASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEY 281
Query: 371 -GCSAIADTGTSLIAGPSKEVEALNAAVGATA 279
+I D+GT+ + P K EA ++ A +
Sbjct: 282 NYDKSIVDSGTTNLRLPKKVFEAAVKSIKAAS 313
>AF201468-1|AAF18982.1| 501|Homo sapiens APP beta-secretase
protein.
Length = 501
Score = 44.4 bits (100), Expect = 4e-04
Identities = 44/152 (28%), Positives = 73/152 (48%), Gaps = 16/152 (10%)
Frame = -2
Query: 686 AVSEPGLAFV-AAKFDGILGMAFSTIAV--DHVTPVFDNMVAQGLVQPVFS-------FY 537
A++E F+ + ++GILG+A++ IA D + P FD++V Q V +FS F
Sbjct: 162 AITESDKFFINGSNWEGILGLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFP 221
Query: 536 LNRDPG-ATTXXXXXXXGSDPAHYRGDLVRVPLLRDTYWEFHMDSVNVNASRF---CAQ- 372
LN+ A+ G D + Y G L P+ R+ Y+E + V +N C +
Sbjct: 222 LNQSEVLASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEY 281
Query: 371 -GCSAIADTGTSLIAGPSKEVEALNAAVGATA 279
+I D+GT+ + P K EA ++ A +
Sbjct: 282 NYDKSIVDSGTTNLRLPKKVFEAAVKSIKAAS 313
>AF200343-1|AAF17079.1| 501|Homo sapiens aspartyl protease 2
protein.
Length = 501
Score = 44.4 bits (100), Expect = 4e-04
Identities = 44/152 (28%), Positives = 73/152 (48%), Gaps = 16/152 (10%)
Frame = -2
Query: 686 AVSEPGLAFV-AAKFDGILGMAFSTIAV--DHVTPVFDNMVAQGLVQPVFS-------FY 537
A++E F+ + ++GILG+A++ IA D + P FD++V Q V +FS F
Sbjct: 162 AITESDKFFINGSNWEGILGLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFP 221
Query: 536 LNRDPG-ATTXXXXXXXGSDPAHYRGDLVRVPLLRDTYWEFHMDSVNVNASRF---CAQ- 372
LN+ A+ G D + Y G L P+ R+ Y+E + V +N C +
Sbjct: 222 LNQSEVLASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEY 281
Query: 371 -GCSAIADTGTSLIAGPSKEVEALNAAVGATA 279
+I D+GT+ + P K EA ++ A +
Sbjct: 282 NYDKSIVDSGTTNLRLPKKVFEAAVKSIKAAS 313
>AF200193-1|AAF13715.1| 488|Homo sapiens memapsin 2 protein.
Length = 488
Score = 44.4 bits (100), Expect = 4e-04
Identities = 44/152 (28%), Positives = 73/152 (48%), Gaps = 16/152 (10%)
Frame = -2
Query: 686 AVSEPGLAFV-AAKFDGILGMAFSTIAV--DHVTPVFDNMVAQGLVQPVFS-------FY 537
A++E F+ + ++GILG+A++ IA D + P FD++V Q V +FS F
Sbjct: 149 AITESDKFFINGSNWEGILGLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFP 208
Query: 536 LNRDPG-ATTXXXXXXXGSDPAHYRGDLVRVPLLRDTYWEFHMDSVNVNASRF---CAQ- 372
LN+ A+ G D + Y G L P+ R+ Y+E + V +N C +
Sbjct: 209 LNQSEVLASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEY 268
Query: 371 -GCSAIADTGTSLIAGPSKEVEALNAAVGATA 279
+I D+GT+ + P K EA ++ A +
Sbjct: 269 NYDKSIVDSGTTNLRLPKKVFEAAVKSIKAAS 300
>AF190725-1|AAF04142.1| 501|Homo sapiens beta-site APP cleaving
enzyme protein.
Length = 501
Score = 44.4 bits (100), Expect = 4e-04
Identities = 44/152 (28%), Positives = 73/152 (48%), Gaps = 16/152 (10%)
Frame = -2
Query: 686 AVSEPGLAFV-AAKFDGILGMAFSTIAV--DHVTPVFDNMVAQGLVQPVFS-------FY 537
A++E F+ + ++GILG+A++ IA D + P FD++V Q V +FS F
Sbjct: 162 AITESDKFFINGSNWEGILGLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFP 221
Query: 536 LNRDPG-ATTXXXXXXXGSDPAHYRGDLVRVPLLRDTYWEFHMDSVNVNASRF---CAQ- 372
LN+ A+ G D + Y G L P+ R+ Y+E + V +N C +
Sbjct: 222 LNQSEVLASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEY 281
Query: 371 -GCSAIADTGTSLIAGPSKEVEALNAAVGATA 279
+I D+GT+ + P K EA ++ A +
Sbjct: 282 NYDKSIVDSGTTNLRLPKKVFEAAVKSIKAAS 313
>AB177847-1|BAD66825.1| 396|Homo sapiens KIAA1149 splice variant 1
protein.
Length = 396
Score = 44.4 bits (100), Expect = 4e-04
Identities = 44/152 (28%), Positives = 73/152 (48%), Gaps = 16/152 (10%)
Frame = -2
Query: 686 AVSEPGLAFV-AAKFDGILGMAFSTIAV--DHVTPVFDNMVAQGLVQPVFS-------FY 537
A++E F+ + ++GILG+A++ IA D + P FD++V Q V +FS F
Sbjct: 57 AITESDKFFINGSNWEGILGLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFP 116
Query: 536 LNRDPG-ATTXXXXXXXGSDPAHYRGDLVRVPLLRDTYWEFHMDSVNVNASRF---CAQ- 372
LN+ A+ G D + Y G L P+ R+ Y+E + V +N C +
Sbjct: 117 LNQSEVLASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEY 176
Query: 371 -GCSAIADTGTSLIAGPSKEVEALNAAVGATA 279
+I D+GT+ + P K EA ++ A +
Sbjct: 177 NYDKSIVDSGTTNLRLPKKVFEAAVKSIKAAS 208
>AB032975-1|BAA86463.2| 532|Homo sapiens KIAA1149 protein protein.
Length = 532
Score = 44.4 bits (100), Expect = 4e-04
Identities = 44/152 (28%), Positives = 73/152 (48%), Gaps = 16/152 (10%)
Frame = -2
Query: 686 AVSEPGLAFV-AAKFDGILGMAFSTIAV--DHVTPVFDNMVAQGLVQPVFS-------FY 537
A++E F+ + ++GILG+A++ IA D + P FD++V Q V +FS F
Sbjct: 193 AITESDKFFINGSNWEGILGLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFP 252
Query: 536 LNRDPG-ATTXXXXXXXGSDPAHYRGDLVRVPLLRDTYWEFHMDSVNVNASRF---CAQ- 372
LN+ A+ G D + Y G L P+ R+ Y+E + V +N C +
Sbjct: 253 LNQSEVLASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEY 312
Query: 371 -GCSAIADTGTSLIAGPSKEVEALNAAVGATA 279
+I D+GT+ + P K EA ++ A +
Sbjct: 313 NYDKSIVDSGTTNLRLPKKVFEAAVKSIKAAS 344
>AF338817-1|AAK38375.1| 457|Homo sapiens beta-site APP cleaving
enzyme type C protein.
Length = 457
Score = 34.7 bits (76), Expect = 0.35
Identities = 38/141 (26%), Positives = 63/141 (44%), Gaps = 13/141 (9%)
Frame = -2
Query: 662 FVAAKFDGILGMAFSTIAVDHVTPVFDNMVAQGLVQPVFS-------FYLNRDPG-ATTX 507
+ K++G LG + + D + P FD++V Q V +FS F LN+ A+
Sbjct: 132 YTQGKWEGELG---TDLPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVG 188
Query: 506 XXXXXXGSDPAHYRGDLVRVPLLRDTYWEFHMDSVNVNASRF---CAQ--GCSAIADTGT 342
G D + Y G L P+ R+ Y+E + V +N C + +I D+GT
Sbjct: 189 GSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGT 248
Query: 341 SLIAGPSKEVEALNAAVGATA 279
+ + P K EA ++ A +
Sbjct: 249 TNLRLPKKVFEAAVKSIKAAS 269
>AB050437-1|BAB40932.1| 457|Homo sapiens beta-site APP cleaving
enzyme I-457 protein.
Length = 457
Score = 34.7 bits (76), Expect = 0.35
Identities = 38/141 (26%), Positives = 63/141 (44%), Gaps = 13/141 (9%)
Frame = -2
Query: 662 FVAAKFDGILGMAFSTIAVDHVTPVFDNMVAQGLVQPVFS-------FYLNRDPG-ATTX 507
+ K++G LG + + D + P FD++V Q V +FS F LN+ A+
Sbjct: 132 YTQGKWEGELG---TDLPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVG 188
Query: 506 XXXXXXGSDPAHYRGDLVRVPLLRDTYWEFHMDSVNVNASRF---CAQ--GCSAIADTGT 342
G D + Y G L P+ R+ Y+E + V +N C + +I D+GT
Sbjct: 189 GSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGT 248
Query: 341 SLIAGPSKEVEALNAAVGATA 279
+ + P K EA ++ A +
Sbjct: 249 TNLRLPKKVFEAAVKSIKAAS 269
>AK125511-1|BAC86188.1| 559|Homo sapiens rome) (ELN). protein.
Length = 559
Score = 32.7 bits (71), Expect = 1.4
Identities = 14/30 (46%), Positives = 16/30 (53%), Gaps = 2/30 (6%)
Frame = -3
Query: 163 WRNSGTRCACPASW--RWTCRSPWALCGSW 80
WR S RC SW W+ R W+ CGSW
Sbjct: 459 WRGSWCRCGS-WSWLGSWSWRGSWSWCGSW 487
>AK126042-1|BAC86409.1| 265|Homo sapiens protein ( Homo sapiens
cDNA FLJ44054 fis, clone TESTI4034212. ).
Length = 265
Score = 31.9 bits (69), Expect = 2.5
Identities = 21/60 (35%), Positives = 29/60 (48%)
Frame = +3
Query: 516 RPGVPVEIEREDGLHESLSHHVVEHRGHMVHCDSAEGHPEDPVELGGHEGKPGLRHGLGE 695
RPGV +R + E L HH + GH+VH + E P L H+ PG+ LG+
Sbjct: 35 RPGV--SHQRAERAFELLLHHDQDALGHLVHVCVHQSCSESPQGL-FHDAHPGVTLTLGQ 91
>Z97652-2|CAM26431.1| 1269|Homo sapiens Crm, cramped-like
(Drosophila) protein.
Length = 1269
Score = 29.9 bits (64), Expect = 10.0
Identities = 19/54 (35%), Positives = 23/54 (42%)
Frame = +1
Query: 265 CPKAMAVAPTAALRASTSLEGPAISDVPVSAMAEQPWAQKRLALTLTESMWNSQ 426
C K +A AP L+ S GP S +A + RLA L E WN Q
Sbjct: 628 CTKDLADAPAEELQEKGSPAGPPPSQGQPAARPPKEVPASRLAQQLREEGWNLQ 681
>U94332-1|AAB53709.1| 401|Homo sapiens osteoprotegerin protein.
Length = 401
Score = 29.9 bits (64), Expect = 10.0
Identities = 13/25 (52%), Positives = 15/25 (60%), Gaps = 1/25 (4%)
Frame = +1
Query: 88 HRG-PMGFGTSSAMKPDRHTVCPNC 159
HR P GFG A P+R+TVC C
Sbjct: 121 HRSCPPGFGVVQAGTPERNTVCKRC 145
>BC146661-1|AAI46662.1| 686|Homo sapiens STIM2 protein protein.
Length = 686
Score = 29.9 bits (64), Expect = 10.0
Identities = 20/55 (36%), Positives = 25/55 (45%), Gaps = 2/55 (3%)
Frame = -1
Query: 237 APAASHLYHRRERLHARGQRLRAPGGA--IRAHGVPVRLHGAGRAEAHGPSVDPG 79
AP S RR R + AP GA ++A G P+R H A H P+ PG
Sbjct: 20 APGGSPCLRRRGRPEESPAAVVAPRGAGELQAAGAPLRFHPASPRRLH-PASTPG 73
>BC030155-1|AAH30155.1| 401|Homo sapiens tumor necrosis factor
receptor superfamily, member 11b (osteoprotegerin)
protein.
Length = 401
Score = 29.9 bits (64), Expect = 10.0
Identities = 13/25 (52%), Positives = 15/25 (60%), Gaps = 1/25 (4%)
Frame = +1
Query: 88 HRG-PMGFGTSSAMKPDRHTVCPNC 159
HR P GFG A P+R+TVC C
Sbjct: 121 HRSCPPGFGVVQAGTPERNTVCKRC 145
>AY466112-1|AAR23265.1| 401|Homo sapiens tumor necrosis factor
receptor superfamily, member 11b (osteoprotegerin)
protein.
Length = 401
Score = 29.9 bits (64), Expect = 10.0
Identities = 13/25 (52%), Positives = 15/25 (60%), Gaps = 1/25 (4%)
Frame = +1
Query: 88 HRG-PMGFGTSSAMKPDRHTVCPNC 159
HR P GFG A P+R+TVC C
Sbjct: 121 HRSCPPGFGVVQAGTPERNTVCKRC 145
>AL162426-8|CAI41183.1| 520|Homo sapiens chromosome 9 open reading
frame 117 protein.
Length = 520
Score = 29.9 bits (64), Expect = 10.0
Identities = 14/41 (34%), Positives = 22/41 (53%)
Frame = +3
Query: 45 ELRVVLADEHVPQDPQRAHGLRHVQRHEAGQAHRVPELRHP 167
+L +V H+P +PQ L ++ R +AH PE+R P
Sbjct: 461 DLGLVPRQVHIPPNPQDLRLLSYITRVGTFRAHSSPEMRAP 501
>AL031708-1|CAM26357.1| 1269|Homo sapiens Crm, cramped-like
(Drosophila) protein.
Length = 1269
Score = 29.9 bits (64), Expect = 10.0
Identities = 19/54 (35%), Positives = 23/54 (42%)
Frame = +1
Query: 265 CPKAMAVAPTAALRASTSLEGPAISDVPVSAMAEQPWAQKRLALTLTESMWNSQ 426
C K +A AP L+ S GP S +A + RLA L E WN Q
Sbjct: 628 CTKDLADAPAEELQEKGSPAGPPPSQGQPAARPPKEVPASRLAQQLREEGWNLQ 681
>AL031009-1|CAM26477.1| 1269|Homo sapiens Crm, cramped-like
(Drosophila) protein.
Length = 1269
Score = 29.9 bits (64), Expect = 10.0
Identities = 19/54 (35%), Positives = 23/54 (42%)
Frame = +1
Query: 265 CPKAMAVAPTAALRASTSLEGPAISDVPVSAMAEQPWAQKRLALTLTESMWNSQ 426
C K +A AP L+ S GP S +A + RLA L E WN Q
Sbjct: 628 CTKDLADAPAEELQEKGSPAGPPPSQGQPAARPPKEVPASRLAQQLREEGWNLQ 681
>AK223155-1|BAD96875.1| 401|Homo sapiens osteoprotegerin precursor
variant protein.
Length = 401
Score = 29.9 bits (64), Expect = 10.0
Identities = 13/25 (52%), Positives = 15/25 (60%), Gaps = 1/25 (4%)
Frame = +1
Query: 88 HRG-PMGFGTSSAMKPDRHTVCPNC 159
HR P GFG A P+R+TVC C
Sbjct: 121 HRSCPPGFGVVQAGTPERNTVCKRC 145
>AF134187-1|AAF20168.1| 372|Homo sapiens osteoprotegerin protein.
Length = 372
Score = 29.9 bits (64), Expect = 10.0
Identities = 13/25 (52%), Positives = 15/25 (60%), Gaps = 1/25 (4%)
Frame = +1
Query: 88 HRG-PMGFGTSSAMKPDRHTVCPNC 159
HR P GFG A P+R+TVC C
Sbjct: 100 HRSCPPGFGVVQAGTPERNTVCKRC 124
>AE006639-2|AAK61288.1| 1587|Homo sapiens unknown protein.
Length = 1587
Score = 29.9 bits (64), Expect = 10.0
Identities = 19/54 (35%), Positives = 23/54 (42%)
Frame = +1
Query: 265 CPKAMAVAPTAALRASTSLEGPAISDVPVSAMAEQPWAQKRLALTLTESMWNSQ 426
C K +A AP L+ S GP S +A + RLA L E WN Q
Sbjct: 880 CTKDLADAPAEELQEKGSPAGPPPSQGQPAARPPKEVPASRLAQQLREEGWNLQ 933
>AB040915-1|BAA96006.1| 818|Homo sapiens KIAA1482 protein protein.
Length = 818
Score = 29.9 bits (64), Expect = 10.0
Identities = 20/55 (36%), Positives = 25/55 (45%), Gaps = 2/55 (3%)
Frame = -1
Query: 237 APAASHLYHRRERLHARGQRLRAPGGA--IRAHGVPVRLHGAGRAEAHGPSVDPG 79
AP S RR R + AP GA ++A G P+R H A H P+ PG
Sbjct: 5 APGGSPCLRRRGRPEESPAAVVAPRGAGELQAAGAPLRFHPASPRRLH-PASTPG 58
>AB037847-1|BAA92664.2| 1066|Homo sapiens KIAA1426 protein protein.
Length = 1066
Score = 29.9 bits (64), Expect = 10.0
Identities = 19/54 (35%), Positives = 23/54 (42%)
Frame = +1
Query: 265 CPKAMAVAPTAALRASTSLEGPAISDVPVSAMAEQPWAQKRLALTLTESMWNSQ 426
C K +A AP L+ S GP S +A + RLA L E WN Q
Sbjct: 425 CTKDLADAPAEELQEKGSPAGPPPSQGQPAARPPKEVPASRLAQQLREEGWNLQ 478
>AB008822-1|BAA32076.1| 401|Homo sapiens osteoclastogenesis
inhibitory factor protein.
Length = 401
Score = 29.9 bits (64), Expect = 10.0
Identities = 13/25 (52%), Positives = 15/25 (60%), Gaps = 1/25 (4%)
Frame = +1
Query: 88 HRG-PMGFGTSSAMKPDRHTVCPNC 159
HR P GFG A P+R+TVC C
Sbjct: 121 HRSCPPGFGVVQAGTPERNTVCKRC 145
>AB002146-1|BAA25910.1| 401|Homo sapiens osteoclastogenesis
inhibitory factor (OCIF) protein.
Length = 401
Score = 29.9 bits (64), Expect = 10.0
Identities = 13/25 (52%), Positives = 15/25 (60%), Gaps = 1/25 (4%)
Frame = +1
Query: 88 HRG-PMGFGTSSAMKPDRHTVCPNC 159
HR P GFG A P+R+TVC C
Sbjct: 121 HRSCPPGFGVVQAGTPERNTVCKRC 145
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 111,671,535
Number of Sequences: 237096
Number of extensions: 2523457
Number of successful extensions: 10437
Number of sequences better than 10.0: 82
Number of HSP's better than 10.0 without gapping: 9230
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 10293
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8791154398
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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