Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P15_F_M09
(594 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q56CY6 Cluster: Acetoacetyl-CoA thiolase; n=5; cellular... 270 2e-71
UniRef50_P24752 Cluster: Acetyl-CoA acetyltransferase, mitochond... 231 1e-59
UniRef50_Q0UU17 Cluster: Putative uncharacterized protein; n=1; ... 180 3e-44
UniRef50_Q6L8K7 Cluster: Acetyl-CoA acetyltransferase; n=40; cel... 180 3e-44
UniRef50_UPI0001509D0E Cluster: acetyl-CoA acyltransferases fami... 167 1e-40
UniRef50_P14611 Cluster: Acetyl-CoA acetyltransferase; n=43; Bac... 166 3e-40
UniRef50_Q8RC88 Cluster: Acetyl-CoA acetyltransferases; n=2; Bac... 165 9e-40
UniRef50_A4G2P1 Cluster: Acetyl-CoA acetyltransferase; n=10; Bac... 157 2e-37
UniRef50_Q87GW1 Cluster: Acetyl-CoA acetyltransferase; n=41; Bac... 153 2e-36
UniRef50_A4SMV2 Cluster: Acetyl-CoA acetyltransferase; n=1; Aero... 151 9e-36
UniRef50_P41338 Cluster: Acetyl-CoA acetyltransferase; n=104; ro... 151 2e-35
UniRef50_Q1GV21 Cluster: Acetyl-CoA C-acetyltransferase; n=66; B... 150 2e-35
UniRef50_Q9K6C8 Cluster: Acetyl-CoA acetyltransferase; n=6; Firm... 148 1e-34
UniRef50_P54810 Cluster: Acetyl-CoA acetyltransferase; n=122; Ba... 145 6e-34
UniRef50_Q67RA4 Cluster: Acetyl-CoA acetyltransferase; n=5; Bact... 144 2e-33
UniRef50_O29070 Cluster: 3-ketoacyl-CoA thiolase; n=2; cellular ... 138 7e-32
UniRef50_A1SHM4 Cluster: Acetyl-CoA acetyltransferases; n=8; Bac... 138 9e-32
UniRef50_A0NJ40 Cluster: Acetyl-CoA C-acetyltransferase-like pro... 137 2e-31
UniRef50_A1WCB0 Cluster: Acetyl-CoA acetyltransferases; n=36; Pr... 135 6e-31
UniRef50_Q577L1 Cluster: PhbA-2, acetyl-CoA acetyltransferase; n... 134 1e-30
UniRef50_Q9BWD1 Cluster: Acetyl-CoA acetyltransferase, cytosolic... 134 2e-30
UniRef50_Q8CAY6 Cluster: Acetyl-CoA acetyltransferase, cytosolic... 131 1e-29
UniRef50_P45855 Cluster: Acetyl-CoA acetyltransferase; n=32; Bac... 129 4e-29
UniRef50_A2DM80 Cluster: Acetyl-CoA acyltransferases family prot... 128 1e-28
UniRef50_Q8D6N4 Cluster: Acetyl-CoA acetyltransferase; n=14; Vib... 126 4e-28
UniRef50_Q6KYW2 Cluster: Acetyl-CoA acetyltransferase; n=4; Ther... 123 3e-27
UniRef50_Q5UX35 Cluster: Acetyl-coA acetyltransferase; n=1; Halo... 123 3e-27
UniRef50_Q2GA69 Cluster: Acetyl-CoA C-acetyltransferase; n=2; Al... 121 1e-26
UniRef50_Q6P3T4 Cluster: ACAT1 protein; n=3; Coelomata|Rep: ACAT... 121 1e-26
UniRef50_Q74IF9 Cluster: Acetyl-CoA acetyltransferase; n=5; Lact... 120 3e-26
UniRef50_Q1VJ45 Cluster: Acetyl-CoA acetyltransferase; n=1; Psyc... 118 1e-25
UniRef50_Q236D4 Cluster: Acetyl-CoA acyltransferases family prot... 118 1e-25
UniRef50_Q835L3 Cluster: Acetyl-CoA acetyltransferase/hydroxymet... 117 2e-25
UniRef50_A1I8P5 Cluster: Acetyl-CoA C-acetyltransferase; n=6; Ba... 115 7e-25
UniRef50_A1SPA4 Cluster: Acetyl-CoA acetyltransferases; n=6; Bac... 115 1e-24
UniRef50_O51136 Cluster: Acetyl-CoA C-acetyltransferase; n=3; Bo... 114 1e-24
UniRef50_Q0AYU4 Cluster: Acetyl-CoA C-acetyltransferase; n=4; Cl... 114 2e-24
UniRef50_Q8SXL6 Cluster: RE07481p; n=1; Drosophila melanogaster|... 112 7e-24
UniRef50_Q43974 Cluster: Beta-ketoadipyl-CoA thiolase; n=274; Ba... 109 5e-23
UniRef50_Q22106 Cluster: Putative uncharacterized protein; n=1; ... 107 3e-22
UniRef50_Q5C0R7 Cluster: SJCHGC03323 protein; n=1; Schistosoma j... 105 6e-22
UniRef50_Q9RRK9 Cluster: Acetyl-CoA acetyltransferase; n=12; Bac... 105 8e-22
UniRef50_A4TXT3 Cluster: Acetyl-CoA acetyltransferase; n=1; Magn... 105 1e-21
UniRef50_Q8ESF0 Cluster: Thiolase B; n=5; Bacteria|Rep: Thiolase... 104 1e-21
UniRef50_Q4TEZ1 Cluster: Chromosome undetermined SCAF4980, whole... 103 3e-21
UniRef50_Q0K0C1 Cluster: Acetyl-CoA acetyltransferase; n=11; Pro... 103 3e-21
UniRef50_Q8ESG3 Cluster: Acetyl-CoA acetyltransferase; n=4; Firm... 101 2e-20
UniRef50_A5UXI0 Cluster: Acetyl-CoA acetyltransferase; n=5; cell... 98 1e-19
UniRef50_Q62JZ3 Cluster: Beta-ketothiolase; n=107; Bacteria|Rep:... 98 2e-19
UniRef50_P73825 Cluster: Acetyl coenzyme A acetyltransferase; n=... 96 5e-19
UniRef50_P42765 Cluster: 3-ketoacyl-CoA thiolase, mitochondrial;... 95 1e-18
UniRef50_A6CQ12 Cluster: Acetyl-CoA acetyltransferase; n=1; Baci... 95 1e-18
UniRef50_Q97W61 Cluster: Acetyl-CoA c-acetyltransferase; n=22; c... 94 3e-18
UniRef50_Q89DN9 Cluster: Acetyl-CoA acetyltransferase; n=1; Brad... 93 3e-18
UniRef50_Q82UG2 Cluster: Thiolase; n=98; Bacteria|Rep: Thiolase ... 93 3e-18
UniRef50_Q0SDR4 Cluster: Acetyl-CoA C-acetyltransferase; n=31; B... 93 6e-18
UniRef50_A6T953 Cluster: Putative acetyl-CoA acetyltransferase; ... 93 6e-18
UniRef50_Q0RXS1 Cluster: Acetyl-CoA C-acetyltransferase; n=1; Rh... 92 1e-17
UniRef50_Q9RZA1 Cluster: Acetyl-CoA acetyltransferase; n=4; root... 91 1e-17
UniRef50_Q8IKW7 Cluster: Acetyl-CoA acetyltransferase, putative;... 90 4e-17
UniRef50_Q9YA31 Cluster: Acetyl-CoA acetyltransferase; n=1; Aero... 88 1e-16
UniRef50_Q21BM7 Cluster: Acetyl-CoA C-acetyltransferase; n=1; Rh... 85 9e-16
UniRef50_A7AWF2 Cluster: Thiolase, N-terminal and C-terminal dom... 84 3e-15
UniRef50_Q0EXX9 Cluster: Acetyl-CoA acyltransferase; n=2; Proteo... 59 3e-15
UniRef50_Q0LKV2 Cluster: Acetyl-CoA C-acyltransferase; n=2; cell... 83 5e-15
UniRef50_Q2QAP2 Cluster: Acetyl-CoA acetyltransferase; n=2; envi... 82 8e-15
UniRef50_A1SXV9 Cluster: Acetyl-CoA acetyltransferases; n=1; Psy... 82 1e-14
UniRef50_A3LMS9 Cluster: Acetyl-CoA C-acyltransferase, peroxisom... 81 1e-14
UniRef50_Q9RUF8 Cluster: Acetyl-CoA acetyltransferase; n=144; ce... 81 3e-14
UniRef50_Q8KXD4 Cluster: Beta-ketothiolase; n=11; Proteobacteria... 81 3e-14
UniRef50_Q7NUH9 Cluster: Acetyl-CoA C-acyltransferase; n=51; Bac... 80 3e-14
UniRef50_Q8SVA6 Cluster: Similarity to 3-KETOACYL COA THIOLASE; ... 79 6e-14
UniRef50_Q9AA29 Cluster: Thiolase family protein; n=42; Bacteria... 79 8e-14
UniRef50_A5UWB8 Cluster: Acetyl-CoA acetyltransferase; n=3; Bact... 79 1e-13
UniRef50_Q39N04 Cluster: Acetyl-CoA C-acetyltransferase; n=29; B... 78 1e-13
UniRef50_A0JWS0 Cluster: Acetyl-CoA acetyltransferases; n=2; Art... 78 1e-13
UniRef50_A3Q406 Cluster: Acetyl-CoA acetyltransferases; n=22; Ac... 78 2e-13
UniRef50_Q8NN21 Cluster: Acetyl-CoA acetyltransferases; n=9; Cor... 77 3e-13
UniRef50_Q2UTB1 Cluster: RIB40 genomic DNA, SC005; n=6; Ascomyco... 77 3e-13
UniRef50_Q2J8N8 Cluster: Acetyl-CoA C-acyltransferase; n=64; Bac... 77 4e-13
UniRef50_Q128L5 Cluster: Acetyl-CoA C-acyltransferase; n=13; Pro... 77 4e-13
UniRef50_Q5P0L6 Cluster: Putative beta-ketothiolase; n=2; Azoarc... 75 1e-12
UniRef50_Q0LZF8 Cluster: Acetyl-CoA C-acetyltransferase; n=3; Ba... 75 1e-12
UniRef50_P21775-2 Cluster: Isoform 2 of P21775 ; n=4; Euarchonto... 75 1e-12
UniRef50_Q8EN18 Cluster: Beta-ketothiolase; n=4; Bacteria|Rep: B... 75 1e-12
UniRef50_Q39TD0 Cluster: Thiolase; n=1; Geobacter metallireducen... 75 1e-12
UniRef50_A1SFE7 Cluster: Acetyl-CoA acetyltransferases; n=11; Ba... 75 1e-12
UniRef50_A0E400 Cluster: Chromosome undetermined scaffold_77, wh... 75 2e-12
UniRef50_UPI000038DFAF Cluster: hypothetical protein Faci_030015... 74 2e-12
UniRef50_P27796 Cluster: 3-ketoacyl-CoA thiolase, peroxisomal pr... 74 3e-12
UniRef50_Q5WL68 Cluster: Acetyl-CoA acetyltransferase; n=1; Baci... 73 7e-12
UniRef50_A1IDF1 Cluster: Acetyl-CoA C-acyltransferase; n=1; Cand... 73 7e-12
UniRef50_Q9KWK4 Cluster: Putative acetyl-CoA C-acetyltransferase... 73 7e-12
UniRef50_Q2RNW4 Cluster: Acetyl-CoA C-acetyltransferase precurso... 72 1e-11
UniRef50_A5DXV8 Cluster: 3-ketoacyl-CoA thiolase B; n=5; Dikarya... 72 1e-11
UniRef50_A1D2F8 Cluster: 3-ketoacyl-CoA ketothiolase (Kat1), put... 72 1e-11
UniRef50_Q08VP3 Cluster: 3-ketoacyl-CoA thiolase; n=1; Stigmatel... 71 2e-11
UniRef50_Q2PQZ1 Cluster: Beta-ketothiolase; n=1; Rhodococcus sp.... 71 2e-11
UniRef50_Q05493 Cluster: 3-ketoacyl-CoA thiolase, peroxisomal pr... 71 2e-11
UniRef50_A6DTH4 Cluster: Acetyl-CoA acetyltransferase; n=1; Lent... 71 3e-11
UniRef50_A0NXK3 Cluster: Acetyl-CoA C-acetyltransferase; n=2; Al... 70 5e-11
UniRef50_P09110 Cluster: 3-ketoacyl-CoA thiolase, peroxisomal pr... 69 6e-11
UniRef50_A0JVH9 Cluster: Acetyl-CoA acetyltransferases; n=20; Ba... 69 8e-11
UniRef50_Q4DNU4 Cluster: Putative uncharacterized protein; n=1; ... 69 8e-11
UniRef50_Q0FF19 Cluster: Putative acetyl-CoA c-acetyltransferase... 69 1e-10
UniRef50_A0LKL0 Cluster: Acetyl-CoA acetyltransferases; n=1; Syn... 69 1e-10
UniRef50_A1W8A4 Cluster: Acetyl-CoA acetyltransferases; n=3; Com... 68 1e-10
UniRef50_A1I8F4 Cluster: Acetyl-CoA C-acyltransferase; n=1; Cand... 68 1e-10
UniRef50_Q02X83 Cluster: Acetyl-CoA acetyltransferase; n=2; Lact... 67 3e-10
UniRef50_Q63YX8 Cluster: Beta-ketoadipyl CoA thiolase; n=96; cel... 67 3e-10
UniRef50_Q89H19 Cluster: Acyl-CoA thiolase; n=4; Proteobacteria|... 66 4e-10
UniRef50_Q2IN02 Cluster: Acetyl-CoA C-acyltransferase; n=3; Myxo... 64 2e-09
UniRef50_Q47DJ3 Cluster: Thiolase; n=2; Bacteria|Rep: Thiolase -... 63 4e-09
UniRef50_Q6ACV5 Cluster: Acetyl-coA acyltransferase; n=2; Actino... 63 5e-09
UniRef50_Q18QM7 Cluster: Acetyl-CoA acetyltransferases; n=2; Des... 62 7e-09
UniRef50_Q4Q698 Cluster: Thiolase protein-like protein; n=7; Try... 62 7e-09
UniRef50_UPI00006D84CA Cluster: COG0183: Acetyl-CoA acetyltransf... 62 1e-08
UniRef50_A4F8Z3 Cluster: Acetyl-CoA acetyltransferase; n=2; Acti... 62 1e-08
UniRef50_Q96CA6 Cluster: ACAA1 protein; n=16; Tetrapoda|Rep: ACA... 46 1e-08
UniRef50_Q8NCW8 Cluster: 3-oxoacyl-CoA thiolase; n=21; Fungi/Met... 62 1e-08
UniRef50_Q5UWD8 Cluster: Acetyl-coA acetyltransferase; n=6; Halo... 61 2e-08
UniRef50_Q5YQT4 Cluster: Putative acyl-CoA thiolase; n=1; Nocard... 60 4e-08
UniRef50_Q1GSM2 Cluster: Acetyl-CoA C-acyltransferase; n=20; Pro... 60 4e-08
UniRef50_Q9HZJ3 Cluster: 3-ketoacyl-CoA thiolase; n=153; Bacteri... 60 5e-08
UniRef50_A0JU34 Cluster: Acetyl-CoA acetyltransferases; n=37; Ac... 59 7e-08
UniRef50_Q11I56 Cluster: Acetyl-CoA acetyltransferases; n=26; Pr... 58 2e-07
UniRef50_P55084 Cluster: Trifunctional enzyme subunit beta, mito... 58 2e-07
UniRef50_Q8F7W4 Cluster: Acetyl-CoA acetyltransferase; n=4; Lept... 57 3e-07
UniRef50_A6GHQ8 Cluster: Acetyl-CoA acetyltransferase; n=1; Ples... 57 3e-07
UniRef50_A4BBG3 Cluster: Acetyl-CoA acetyltransferase; n=1; Rein... 57 3e-07
UniRef50_A0Z3Q6 Cluster: Acetyl-CoA acetyltransferase; n=1; mari... 57 3e-07
UniRef50_Q1GCU4 Cluster: Acetyl-CoA C-acetyltransferase; n=2; Rh... 57 4e-07
UniRef50_Q81Y70 Cluster: Acetyl-CoA acetyltransferase; n=11; Bac... 56 5e-07
UniRef50_Q3INC2 Cluster: Acetyl-CoA C-acyltransferase 5; n=1; Na... 56 6e-07
UniRef50_Q9AG66 Cluster: Beta ketothiolase; n=5; Rhizobiaceae|Re... 55 1e-06
UniRef50_A1FU75 Cluster: Acetyl-CoA acetyltransferases; n=5; Xan... 55 1e-06
UniRef50_A7IGV8 Cluster: Acetyl-CoA acetyltransferase; n=1; Xant... 54 2e-06
UniRef50_Q184F9 Cluster: Putative thiolase; n=2; Clostridium dif... 54 3e-06
UniRef50_A6G214 Cluster: Putative uncharacterized protein; n=1; ... 53 6e-06
UniRef50_A1SKA8 Cluster: Acetyl-CoA acetyltransferases; n=24; Ac... 53 6e-06
UniRef50_Q92GI8 Cluster: Similarity to acetyl-CoA acetyltransfer... 52 8e-06
UniRef50_Q7QZB1 Cluster: GLP_567_7442_8677; n=1; Giardia lamblia... 51 2e-05
UniRef50_Q4TEZ0 Cluster: Chromosome undetermined SCAF4980, whole... 50 3e-05
UniRef50_Q6MM13 Cluster: Acetyl-CoA acyltransferase; n=2; Proteo... 50 3e-05
UniRef50_Q9KT59 Cluster: 3-ketoacyl-CoA thiolase; n=113; Proteob... 50 3e-05
UniRef50_Q1GUF0 Cluster: Acetyl-CoA C-acyltransferase; n=2; Prot... 50 5e-05
UniRef50_UPI000023DFFE Cluster: hypothetical protein FG09503.1; ... 49 9e-05
UniRef50_Q58944 Cluster: Uncharacterized protein MJ1549; n=18; E... 48 2e-04
UniRef50_Q9F8Q0 Cluster: 3-ketoacyl-CoA thiolase; n=1; Carboxydo... 48 2e-04
UniRef50_Q1AV81 Cluster: Thiolase; n=3; Actinobacteria (class)|R... 46 5e-04
UniRef50_Q565U8 Cluster: 3-oxoacyl-CoA thiolase; n=1; uncultured... 44 0.002
UniRef50_Q5VKR9 Cluster: Ketoacyl-ACP synthase; n=2; Saccharopol... 44 0.003
UniRef50_Q1GWY7 Cluster: Acetyl-CoA C-acyltransferase; n=4; Bact... 44 0.004
UniRef50_Q8FQ63 Cluster: Putative lipid-transfer protein; n=1; C... 43 0.005
UniRef50_Q13HG7 Cluster: Acetyl-CoA C-acetyltransferase; n=1; Bu... 43 0.006
UniRef50_Q0QMN6 Cluster: Polyketide synthase type I; n=1; Strept... 42 0.011
UniRef50_Q84FL0 Cluster: AdmM; n=4; Gammaproteobacteria|Rep: Adm... 42 0.014
UniRef50_Q1M689 Cluster: Putative thiolase; n=1; Rhizobium legum... 42 0.014
UniRef50_A6GTF1 Cluster: Acetyl-CoA C-acyltransferase; n=1; Limn... 42 0.014
UniRef50_A6EZZ3 Cluster: Beta-ketoadipyl CoA thiolase PcaF; n=1;... 41 0.019
UniRef50_UPI00006A0465 Cluster: 3-ketoacyl-CoA thiolase, peroxis... 41 0.025
UniRef50_Q9KHD6 Cluster: Type II beta-ketoacyl synthase; n=1; St... 41 0.025
UniRef50_O28040 Cluster: 3-ketoacyl-CoA thiolase; n=12; Archaea|... 41 0.025
UniRef50_O26884 Cluster: Uncharacterized protein MTH_793; n=2; E... 41 0.025
UniRef50_Q9EX53 Cluster: Putative type I polyketide synthase; n=... 40 0.033
UniRef50_Q1D6R4 Cluster: Polyketide synthase type I; n=1; Myxoco... 40 0.033
UniRef50_Q0QMP8 Cluster: Polyketide synthase type I; n=1; Strept... 40 0.033
UniRef50_A6RBW5 Cluster: Putative uncharacterized protein; n=1; ... 40 0.033
UniRef50_Q8U274 Cluster: Acetyl CoA synthase; n=8; Archaea|Rep: ... 40 0.033
UniRef50_Q3A171 Cluster: 3-oxoacyl-(Acyl-carrier-protein) syntha... 40 0.044
UniRef50_Q96X18 Cluster: Acetyl-CoA acetyltransferase; n=1; Lacc... 40 0.044
UniRef50_Q7NDK9 Cluster: Gll4226 protein; n=1; Gloeobacter viola... 40 0.058
UniRef50_Q3ZXT9 Cluster: 3-oxoacyl-[acyl-carrier-protein] syntha... 40 0.058
UniRef50_A5WF94 Cluster: Acetyl-CoA acetyltransferase; n=72; Bac... 40 0.058
UniRef50_A2W1N2 Cluster: Acetyl-CoA acetyltransferase; n=6; Prot... 40 0.058
UniRef50_Q1MX72 Cluster: Type I polyketide synthase; n=2; Strept... 39 0.077
UniRef50_Q0P7K1 Cluster: Putative hybrid non-ribosomal peptide-p... 39 0.077
UniRef50_A3N0P7 Cluster: 3-ketoacyl-CoA thiolase; n=1; Actinobac... 39 0.077
UniRef50_UPI0000DADC27 Cluster: hypothetical protein RcanM_01000... 39 0.10
UniRef50_Q93HI8 Cluster: Modular polyketide synthase; n=1; Strep... 39 0.10
UniRef50_Q5WBW0 Cluster: Acetyl-CoA acetyltransferase; n=1; Baci... 39 0.10
UniRef50_Q84HM3 Cluster: PksE; n=1; Lechevalieria aerocolonigene... 39 0.10
UniRef50_Q6V1M7 Cluster: Plm2-3; n=1; Streptomyces sp. HK803|Rep... 39 0.10
UniRef50_Q3D2X0 Cluster: Thiolase; n=7; Streptococcus agalactiae... 39 0.10
UniRef50_Q1MX73 Cluster: Type I polyketide synthase; n=1; Strept... 38 0.13
UniRef50_Q0QMQ1 Cluster: Polyketide synthase type I; n=1; Strept... 38 0.13
UniRef50_Q09DD1 Cluster: Type I polyketide synthase PikAI; n=1; ... 38 0.13
UniRef50_A4KCE5 Cluster: Tautomycetin biosynthetic PKS; n=1; Str... 38 0.13
UniRef50_Q5XDB2 Cluster: Acetyl-CoA acetyltransferase; n=11; Str... 38 0.18
UniRef50_Q9L8C7 Cluster: Polyketide synthase; n=8; Sorangium cel... 38 0.18
UniRef50_Q83WF0 Cluster: Protomycinolide IV synthase 1; n=18; ce... 38 0.18
UniRef50_Q3W1C5 Cluster: Beta-ketoacyl synthase:Acyl transferase... 38 0.18
UniRef50_A5IHN4 Cluster: 3-oxoacyl-(Acyl carrier protein) syntha... 38 0.18
UniRef50_Q7WTF3 Cluster: NanA3; n=1; Streptomyces nanchangensis|... 38 0.23
UniRef50_Q6JHN6 Cluster: ObsC; n=1; Saccharopolyspora spinosa|Re... 38 0.23
UniRef50_Q4U446 Cluster: DszB; n=2; cellular organisms|Rep: DszB... 38 0.23
UniRef50_Q0VZ72 Cluster: Polyketide synthase; n=1; Chondromyces ... 38 0.23
UniRef50_A7HT85 Cluster: Beta-ketoacyl synthase; n=1; Parvibacul... 38 0.23
UniRef50_A6E0C0 Cluster: Putative uncharacterized protein; n=1; ... 38 0.23
UniRef50_Q9HRI8 Cluster: 3-ketoacyl-CoA thiolase; n=5; Halobacte... 38 0.23
UniRef50_Q9ZGI4 Cluster: Type I polyketide synthase PikAII; n=2;... 37 0.31
UniRef50_Q93NX9 Cluster: AmphI; n=5; Bacteria|Rep: AmphI - Strep... 37 0.31
UniRef50_Q5VKQ8 Cluster: Type I PKS; n=3; Saccharopolyspora eryt... 37 0.31
UniRef50_Q52V50 Cluster: Polyketide synthase type I; n=7; cellul... 37 0.31
UniRef50_Q3W1F1 Cluster: Beta-ketoacyl synthase:Acyl transferase... 37 0.31
UniRef50_Q27W58 Cluster: NigAVII; n=6; cellular organisms|Rep: N... 37 0.31
UniRef50_Q0RTS5 Cluster: Putative Type I modular polyketide synt... 37 0.31
UniRef50_Q0LKI5 Cluster: Beta-ketoacyl synthase; n=1; Herpetosip... 37 0.31
UniRef50_A4KCE4 Cluster: Tautomycetin biosynthetic PKS; n=2; cel... 37 0.31
UniRef50_A3K5J3 Cluster: Acetyl-CoA acetyltransferase; n=1; Sagi... 37 0.31
UniRef50_A1YAM7 Cluster: Polyketide synthase type I; n=3; Actino... 37 0.31
UniRef50_A1AMI5 Cluster: Beta-ketoacyl synthase; n=1; Pelobacter... 37 0.31
UniRef50_A0ACH1 Cluster: Putative polyketide synthase B; n=5; Ba... 37 0.31
UniRef50_Q9ALM2 Cluster: Polyketide synthase extender modules 8-... 37 0.41
UniRef50_Q83WE8 Cluster: Protomycinolide IV synthase 3; n=2; Mic... 37 0.41
UniRef50_O30764 Cluster: Polyketide synthase modules 1 and 2; n=... 37 0.41
UniRef50_A1GD41 Cluster: Acyl transferase region; n=1; Salinispo... 37 0.41
UniRef50_Q9S0R3 Cluster: Type I polyketide synthase AVES 4; n=2;... 36 0.54
UniRef50_Q2N3S8 Cluster: Polyketide synthase; n=2; Bacteria|Rep:... 36 0.54
UniRef50_Q1K1L4 Cluster: Beta-hydroxyacyl-(Acyl-carrier-protein)... 36 0.54
UniRef50_Q09DD3 Cluster: MxaC; n=1; Stigmatella aurantiaca DW4/3... 36 0.54
UniRef50_A3R4R6 Cluster: Polyketide synthase; n=1; Streptomyces ... 36 0.54
UniRef50_A1GGE4 Cluster: Beta-ketoacyl synthase; n=1; Salinispor... 36 0.54
UniRef50_A0W5R6 Cluster: Beta-ketoacyl synthase; n=1; Geobacter ... 36 0.54
UniRef50_UPI0000EBE312 Cluster: PREDICTED: similar to Acetyl-Coe... 36 0.72
UniRef50_Q3AZP4 Cluster: Putative 3-oxoacyl-(Acyl-carrier-protei... 36 0.72
UniRef50_Q2J8Q4 Cluster: Beta-ketoacyl synthase; n=1; Frankia sp... 36 0.72
UniRef50_Q93NW6 Cluster: AmphC; n=1; Streptomyces nodosus|Rep: A... 36 0.72
UniRef50_Q8RL72 Cluster: MmpIV; n=3; cellular organisms|Rep: Mmp... 36 0.72
UniRef50_Q846X3 Cluster: Monensin polyketide synthase modules 5 ... 36 0.72
UniRef50_Q846W6 Cluster: Monensin polyketide synthase modules 11... 36 0.72
UniRef50_Q76KY0 Cluster: Polyketide synthase modules 1-3; n=2; c... 36 0.72
UniRef50_Q6VT93 Cluster: Mixed type I polyketide synthase-peptid... 36 0.72
UniRef50_Q6GVP0 Cluster: Possible polyketide synthase; n=15; Act... 36 0.72
UniRef50_Q3VXM8 Cluster: Beta-ketoacyl synthase:Acyl transferase... 36 0.72
UniRef50_Q1Q275 Cluster: Similar to beta-ketoacyl (Acyl carrier ... 36 0.72
UniRef50_Q0VZ73 Cluster: Polyketide synthase; n=1; Chondromyces ... 36 0.72
UniRef50_Q0RLH1 Cluster: Putative polyketide synthase; n=1; Fran... 36 0.72
UniRef50_P95814 Cluster: FK506 polyketide synthase; n=2; Strepto... 36 0.72
UniRef50_A6PQN7 Cluster: Beta-ketoacyl synthase precursor; n=1; ... 36 0.72
UniRef50_A6GK65 Cluster: Polyketide synthase type I; n=2; Plesio... 36 0.72
UniRef50_A6G4P0 Cluster: Putative multi-domain beta keto-acyl sy... 36 0.72
UniRef50_A4FCY9 Cluster: Modular polyketide synthase; n=3; cellu... 36 0.72
UniRef50_A0VU10 Cluster: Beta-ketoacyl synthase; n=1; Dinoroseob... 36 0.72
UniRef50_Q6RKI7 Cluster: Polyketide synthase; n=3; Sclerotiniace... 36 0.72
UniRef50_Q07017 Cluster: Oleandomycin polyketide synthase, modul... 36 0.72
UniRef50_Q93HJ5 Cluster: Modular polyketide synthase; n=5; Actin... 36 0.95
UniRef50_Q9L4X3 Cluster: NysI; n=4; root|Rep: NysI - Streptomyce... 36 0.95
UniRef50_Q93HF2 Cluster: Modular polyketide synthase; n=2; Strep... 36 0.95
UniRef50_Q6W5P6 Cluster: FscD; n=6; Bacteria|Rep: FscD - Strepto... 36 0.95
UniRef50_Q1RS52 Cluster: Polyketide synthase type I; n=3; Bacter... 36 0.95
UniRef50_Q1RS45 Cluster: Polyketide synthase type I; n=4; cellul... 36 0.95
UniRef50_Q0QMN5 Cluster: Polyketide synthase type I; n=1; Strept... 36 0.95
UniRef50_Q02DB0 Cluster: Beta-ketoacyl synthase precursor; n=2; ... 36 0.95
UniRef50_A5FKY0 Cluster: Beta-ketoacyl synthase; n=6; Bacteria|R... 36 0.95
UniRef50_A4X8L0 Cluster: Beta-ketoacyl synthase; n=1; Salinispor... 36 0.95
UniRef50_A4LZ00 Cluster: KR; n=1; Geobacter bemidjiensis Bem|Rep... 36 0.95
UniRef50_A1I964 Cluster: Thiolase; n=4; Proteobacteria|Rep: Thio... 36 0.95
UniRef50_A0EH89 Cluster: Chromosome undetermined scaffold_96, wh... 36 0.95
UniRef50_Q6LS57 Cluster: Omega-3 polyunsaturated fatty acid synt... 35 1.3
UniRef50_Q9EWA1 Cluster: PimS2 protein; n=2; Streptomyces|Rep: P... 35 1.3
UniRef50_Q9ALM6 Cluster: Polyketide synthase loading and extende... 35 1.3
UniRef50_Q8RJX9 Cluster: StiH protein; n=1; Stigmatella aurantia... 35 1.3
UniRef50_Q84HM9 Cluster: PksE; n=17; Actinomycetales|Rep: PksE -... 35 1.3
UniRef50_Q83X69 Cluster: Lankamycin synthase, starter module and... 35 1.3
UniRef50_Q7WTF5 Cluster: NanA1; n=2; Streptomyces|Rep: NanA1 - S... 35 1.3
UniRef50_Q7WTF2 Cluster: NanA4; n=1; Streptomyces nanchangensis|... 35 1.3
UniRef50_Q76KZ5 Cluster: Polyketide synthase modules 4; n=1; Str... 35 1.3
UniRef50_Q6V1N7 Cluster: Plm7; n=1; Streptomyces sp. HK803|Rep: ... 35 1.3
UniRef50_Q3S864 Cluster: Nodular polyketide synthase; n=15; Bact... 35 1.3
UniRef50_Q3S863 Cluster: Modular polyketide synthase; n=1; Strep... 35 1.3
UniRef50_Q27W68 Cluster: NigAVI; n=2; Streptomyces|Rep: NigAVI -... 35 1.3
UniRef50_Q1K0R6 Cluster: Beta-ketoacyl synthase precursor; n=1; ... 35 1.3
UniRef50_Q1JYV0 Cluster: Erythronolide synthase; n=1; Desulfurom... 35 1.3
UniRef50_Q0ILC7 Cluster: NlmA4; n=1; Streptomyces nanchangensis|... 35 1.3
UniRef50_O51827 Cluster: Polyketide synthase type I; n=2; Pseudo... 35 1.3
UniRef50_A5KPS6 Cluster: Putative uncharacterized protein; n=1; ... 35 1.3
UniRef50_A1YAN0 Cluster: Polyketide synthase type I; n=3; cellul... 35 1.3
UniRef50_A1YAM9 Cluster: Polyketide synthase type I; n=5; cellul... 35 1.3
UniRef50_A1FT95 Cluster: Beta-ketoacyl synthase; n=8; Proteobact... 35 1.3
UniRef50_O30201 Cluster: 3-ketoacyl-CoA thiolase; n=1; Archaeogl... 35 1.3
UniRef50_A7DPX4 Cluster: Propanoyl-CoA C-acyltransferase; n=1; C... 35 1.3
UniRef50_Q03132 Cluster: Erythronolide synthase, modules 3 and 4... 35 1.3
UniRef50_Q9FBC2 Cluster: Beta-ketoacyl-ACP synthase II (3-oxoacy... 35 1.7
UniRef50_Q9CDB1 Cluster: Polyketide synthase; n=12; Mycobacteriu... 35 1.7
UniRef50_Q93HH0 Cluster: Modular polyketide synthase; n=1; Strep... 35 1.7
UniRef50_Q820T4 Cluster: 3-oxoacyl-(Acyl-carrier-protein) syntha... 35 1.7
UniRef50_Q846X2 Cluster: Monensin polyketide synthase modules 7 ... 35 1.7
UniRef50_Q6TLJ9 Cluster: Polyketide synthase type I; n=1; Pseudo... 35 1.7
UniRef50_Q49HL2 Cluster: SA1_PKSA; n=65; cellular organisms|Rep:... 35 1.7
UniRef50_Q3WH62 Cluster: Beta-ketoacyl synthase:Thioesterase:Acy... 35 1.7
UniRef50_Q3S868 Cluster: Modular polyketide synthase; n=1; Strep... 35 1.7
UniRef50_Q197Z2 Cluster: SalB; n=1; Streptomyces albus|Rep: SalB... 35 1.7
UniRef50_Q0S8W4 Cluster: Type I polyketide synthase; n=2; Rhodoc... 35 1.7
UniRef50_Q0R4M5 Cluster: ChlA3; n=3; Streptomyces antibioticus|R... 35 1.7
UniRef50_Q0B257 Cluster: Beta-ketoacyl synthase; n=2; Burkholder... 35 1.7
UniRef50_Q099Y5 Cluster: Oxidoreductase, short chain dehydrogena... 35 1.7
UniRef50_A6PQQ3 Cluster: Beta-ketoacyl synthase; n=1; Victivalli... 35 1.7
UniRef50_A4X3P8 Cluster: Beta-ketoacyl synthase; n=1; Salinispor... 35 1.7
UniRef50_A1S4L4 Cluster: Omega-3 polyunsaturated fatty acid synt... 35 1.7
UniRef50_A1I9L6 Cluster: Polyketide synthase modules and related... 35 1.7
UniRef50_Q1E349 Cluster: Putative uncharacterized protein; n=1; ... 35 1.7
UniRef50_A2QWP6 Cluster: Catalytic activity: 6 Malonyl-CoA + Pro... 35 1.7
UniRef50_Q93HJ4 Cluster: OlmA2 protein; n=1; Streptomyces avermi... 34 2.2
UniRef50_Q9L4W3 Cluster: NysC; n=3; Actinomycetales|Rep: NysC - ... 34 2.2
UniRef50_Q9KIZ6 Cluster: EpoE; n=2; Sorangium cellulosum|Rep: Ep... 34 2.2
UniRef50_Q8KUH4 Cluster: Polyketide synthase; n=1; Actinosynnema... 34 2.2
UniRef50_Q84DF6 Cluster: Type I polyketide synthase-like; n=4; B... 34 2.2
UniRef50_Q83TF5 Cluster: Warhead-forming iterative polyketide sy... 34 2.2
UniRef50_Q6W5P8 Cluster: FscF; n=3; Streptomyces|Rep: FscF - Str... 34 2.2
UniRef50_Q6JHN8 Cluster: ObsA; n=3; Actinomycetales|Rep: ObsA - ... 34 2.2
UniRef50_Q0JZY9 Cluster: Probable lipid-transfer protein; n=3; B... 34 2.2
UniRef50_A1SP80 Cluster: Beta-ketoacyl synthase precursor; n=1; ... 34 2.2
UniRef50_A0FCL2 Cluster: MerB; n=4; cellular organisms|Rep: MerB... 34 2.2
UniRef50_Q3IRP5 Cluster: Acetyl-CoA C-acyltransferase 8; n=1; Na... 34 2.2
UniRef50_Q9S0R4 Cluster: Type I polyketide synthase AVES 3; n=1;... 34 2.9
UniRef50_Q93HJ2 Cluster: Modular polyketide synthase; n=6; Bacte... 34 2.9
UniRef50_Q93HH9 Cluster: Modular polyketide synthase; n=1; Strep... 34 2.9
UniRef50_Q9KIZ5 Cluster: EpoF; n=2; Sorangium cellulosum|Rep: Ep... 34 2.9
UniRef50_Q9KIV4 Cluster: 8,8a-deoxyoleandolide synthase 1; n=1; ... 34 2.9
UniRef50_Q846X6 Cluster: Monensin polyketide synthase loading mo... 34 2.9
UniRef50_Q75V76 Cluster: PhlC; n=18; Pseudomonas|Rep: PhlC - Pse... 34 2.9
UniRef50_Q5W262 Cluster: Putative Beta-ketomyristol-ACP synthase... 34 2.9
UniRef50_Q3S869 Cluster: Modular polyketide synthase; n=2; Strep... 34 2.9
UniRef50_Q32YY0 Cluster: Polyketide synthase ketosynthase domain... 34 2.9
UniRef50_Q21RA6 Cluster: Beta-ketoacyl synthase; n=2; Betaproteo... 34 2.9
UniRef50_Q1MX81 Cluster: Type I polyketide synthase; n=2; Strept... 34 2.9
UniRef50_Q0RKW8 Cluster: Putative multi-domain beta-ketoacyl syn... 34 2.9
UniRef50_A5GFJ7 Cluster: Erythronolide synthase; n=2; Desulfurom... 34 2.9
UniRef50_A4SVV8 Cluster: Beta-ketoacyl synthase; n=60; Bacteria|... 34 2.9
UniRef50_A4LZ01 Cluster: Beta-ketoacyl synthase; n=2; cellular o... 34 2.9
UniRef50_A4FDM8 Cluster: Modular polyketide synthase-; n=1; Sacc... 34 2.9
UniRef50_A4F5D6 Cluster: Polyketide synthase; n=5; cellular orga... 34 2.9
UniRef50_A3QGD5 Cluster: Beta-hydroxyacyl-(Acyl-carrier-protein)... 34 2.9
UniRef50_A1YBQ4 Cluster: AmbC; n=8; Sorangium cellulosum|Rep: Am... 34 2.9
UniRef50_A1YAM6 Cluster: Polyketide synthase type I; n=2; Actino... 34 2.9
UniRef50_A0UUS3 Cluster: Beta-ketoacyl synthase; n=1; Clostridiu... 34 2.9
UniRef50_O29811 Cluster: 3-ketoacyl-CoA thiolase; n=6; Archaea|R... 34 2.9
UniRef50_Q93H85 Cluster: Modular polyketide synthase; n=4; Bacte... 33 3.8
UniRef50_Q82QT4 Cluster: Modular polyketide synthase; n=3; Strep... 33 3.8
UniRef50_Q63LK8 Cluster: Putative polyketide synthase; n=30; cel... 33 3.8
UniRef50_Q8RJY6 Cluster: StiA protein; n=1; Stigmatella aurantia... 33 3.8
UniRef50_Q8GBX4 Cluster: Polyketide synthase; n=2; Sorangium cel... 33 3.8
UniRef50_Q84HI8 Cluster: PksE; n=2; Micromonospora chersina|Rep:... 33 3.8
UniRef50_Q846X4 Cluster: Monensin polyketide synthase modules 3 ... 33 3.8
UniRef50_Q6W5P9 Cluster: FscB; n=6; Streptomyces|Rep: FscB - Str... 33 3.8
UniRef50_Q5SFB2 Cluster: Polyketide synthase subunit; n=2; Strep... 33 3.8
UniRef50_Q4U447 Cluster: DszA; n=4; cellular organisms|Rep: DszA... 33 3.8
UniRef50_Q4AHS5 Cluster: Beta-ketoacyl synthase:Beta-ketoacyl sy... 33 3.8
UniRef50_Q3W495 Cluster: Beta-ketoacyl synthase:Acyl transferase... 33 3.8
UniRef50_Q1WEK8 Cluster: Polyketide synthase; n=1; Streptomyces ... 33 3.8
UniRef50_Q0RR72 Cluster: Putative Polyketide synthase; n=1; Fran... 33 3.8
UniRef50_Q0QMN7 Cluster: Polyketide synthase type I; n=1; Strept... 33 3.8
UniRef50_Q0PD02 Cluster: Type I polyketide synthase; n=2; Strept... 33 3.8
UniRef50_Q0IDS9 Cluster: Polyketide synthase, putative; n=1; Syn... 33 3.8
UniRef50_Q0B307 Cluster: Beta-ketoacyl synthase; n=1; Burkholder... 33 3.8
UniRef50_O54666 Cluster: RifA; n=4; Actinomycetales|Rep: RifA - ... 33 3.8
UniRef50_O33956 Cluster: Tylactone synthase modules 4 & 5; n=1; ... 33 3.8
UniRef50_O33954 Cluster: Tylactone synthase starter module and m... 33 3.8
UniRef50_O30768 Cluster: Polyketide synthase module 7; n=1; Stre... 33 3.8
UniRef50_O30766 Cluster: Polyketide synthase modules 4 and 5; n=... 33 3.8
UniRef50_A6GKP5 Cluster: Modular polyketide synthase; n=1; Plesi... 33 3.8
UniRef50_A6FZ63 Cluster: Nonribosomal peptide synthase; n=1; Ple... 33 3.8
UniRef50_A4F5Q0 Cluster: Putative multi-domain beta-ketoacyl syn... 33 3.8
UniRef50_A1YBQ3 Cluster: AmbB; n=2; Sorangium cellulosum|Rep: Am... 33 3.8
UniRef50_A0MS25 Cluster: BryB; n=2; Candidatus Endobugula sertul... 33 3.8
UniRef50_Q6RKE2 Cluster: Polyketide synthase; n=2; Pleosporales|... 33 3.8
UniRef50_A5PHD6 Cluster: Methylorcinaldehyde synthase; n=1; Acre... 33 3.8
UniRef50_A1CVN0 Cluster: Polyketide synthase, putative; n=9; Fun... 33 3.8
UniRef50_Q6L234 Cluster: Beta-ketoacyl synthase; n=5; Thermoplas... 33 3.8
UniRef50_Q9S0R7 Cluster: Type I polyketide synthase AVES 2; n=1;... 33 5.0
UniRef50_Q982I5 Cluster: Polyketide synthase; n=1; Mesorhizobium... 33 5.0
UniRef50_Q93HJ1 Cluster: Modular polyketide synthase; n=2; Strep... 33 5.0
UniRef50_Q93H84 Cluster: Modular polyketide synthase; n=2; Strep... 33 5.0
UniRef50_Q8E9A1 Cluster: 3-oxoacyl-(Acyl-carrier-protein) syntha... 33 5.0
UniRef50_Q7NDL0 Cluster: Gll4225 protein; n=1; Gloeobacter viola... 33 5.0
UniRef50_Q5YRL8 Cluster: Putative polyketide synthase; n=2; Noca... 33 5.0
UniRef50_Q4KCD7 Cluster: Nonribosomal peptide synthase; n=1; Pse... 33 5.0
UniRef50_Q2J7A5 Cluster: Beta-ketoacyl synthase; n=5; Actinomyce... 33 5.0
UniRef50_Q2IGF9 Cluster: Beta-ketoacyl synthase, Acyl transferas... 33 5.0
UniRef50_Q9L4X1 Cluster: NysK; n=1; Streptomyces noursei|Rep: Ny... 33 5.0
UniRef50_Q5SFB3 Cluster: Polyketide synthase subunit; n=2; Strep... 33 5.0
UniRef50_Q52V53 Cluster: Polyketide synthase type I; n=4; cellul... 33 5.0
UniRef50_Q1D5G1 Cluster: Polyketide synthase; n=1; Myxococcus xa... 33 5.0
UniRef50_Q11Y42 Cluster: 3-oxoacyl-[acyl-carrier-protein] syntha... 33 5.0
UniRef50_Q0PCZ9 Cluster: Type I polyketide synthase; n=2; Strept... 33 5.0
UniRef50_O30479 Cluster: PKS module 1; n=2; Streptomyces hygrosc... 33 5.0
UniRef50_A6PNE6 Cluster: Beta-ketoacyl synthase; n=1; Victivalli... 33 5.0
UniRef50_A5G9M9 Cluster: Thiolase; n=2; cellular organisms|Rep: ... 33 5.0
UniRef50_A5G642 Cluster: Beta-ketoacyl synthase; n=1; Geobacter ... 33 5.0
UniRef50_A4PHN0 Cluster: Hybrid polyketide synthase-non ribosoma... 33 5.0
UniRef50_A3YET0 Cluster: Putative uncharacterized protein; n=1; ... 33 5.0
UniRef50_A0PWX0 Cluster: Lipid-transfer protein Ltp1_1; n=3; Act... 33 5.0
UniRef50_A0GPF1 Cluster: Thiolase; n=6; Proteobacteria|Rep: Thio... 33 5.0
UniRef50_A3CT30 Cluster: ABC transporter-related protein; n=2; M... 33 5.0
UniRef50_Q97HK3 Cluster: 3-oxoacyl-(Acyl-carrier-protein) syntha... 33 6.7
UniRef50_Q93HI0 Cluster: Modular polyketide synthase; n=1; Strep... 33 6.7
UniRef50_Q6AM47 Cluster: Related to 3-oxoacyl-acyl carrier prote... 33 6.7
UniRef50_Q9L4X2 Cluster: NysJ; n=3; Streptomyces|Rep: NysJ - Str... 33 6.7
UniRef50_Q9KIV3 Cluster: 8,8a-deoxyoleandolide synthase 2; n=2; ... 33 6.7
UniRef50_Q8KUH3 Cluster: Polyketide synthase; n=2; Bacteria|Rep:... 33 6.7
UniRef50_Q6TEI0 Cluster: Type I polyketide synthase; n=1; Strept... 33 6.7
UniRef50_Q5VKR4 Cluster: Type I PKS; n=7; Actinomycetales|Rep: T... 33 6.7
UniRef50_Q2PC83 Cluster: Putative polyketide synthase; n=2; Acti... 33 6.7
UniRef50_Q2ANX1 Cluster: Beta-ketoacyl synthase:Acyl transferase... 33 6.7
UniRef50_Q21MX9 Cluster: Beta-ketoacyl synthase; n=1; Saccharoph... 33 6.7
UniRef50_Q1MX64 Cluster: Type I polyketide synthase-related prot... 33 6.7
UniRef50_Q1L0S5 Cluster: NapD; n=4; Streptomyces hygroscopicus|R... 33 6.7
UniRef50_Q0RQ47 Cluster: Modular polyketide synthase; n=4; Bacte... 33 6.7
UniRef50_Q0B308 Cluster: Beta-ketoacyl synthase; n=1; Burkholder... 33 6.7
UniRef50_Q090E0 Cluster: Oxidoreductase, short chain dehydrogena... 33 6.7
UniRef50_A6G5B6 Cluster: Modular polyketide synthase; n=1; Plesi... 33 6.7
UniRef50_A5N8Z2 Cluster: Predicted polyketide synthase; n=1; Clo... 33 6.7
UniRef50_A4X8M0 Cluster: Beta-ketoacyl synthase; n=2; Salinispor... 33 6.7
UniRef50_A4X2H8 Cluster: Beta-ketoacyl synthase; n=1; Salinispor... 33 6.7
UniRef50_A4FIG8 Cluster: Modular polyketide synthase; n=1; Sacch... 33 6.7
UniRef50_A3ZWB0 Cluster: Probable multi-domain beta keto-acyl sy... 33 6.7
UniRef50_A2VH86 Cluster: Polyketide beta-ketoacyl synthase pks4;... 33 6.7
UniRef50_A1YBR0 Cluster: AmbH; n=1; Sorangium cellulosum|Rep: Am... 33 6.7
UniRef50_A1GFR6 Cluster: AMP-dependent synthetase and ligase; n=... 33 6.7
UniRef50_A1G9R2 Cluster: Beta-ketoacyl synthase; n=3; cellular o... 33 6.7
UniRef50_A1B0A4 Cluster: Beta-ketoacyl synthase; n=1; Paracoccus... 33 6.7
UniRef50_A0UXD4 Cluster: Condensation domain; n=1; Clostridium c... 33 6.7
UniRef50_A0FCL1 Cluster: MerA; n=2; Streptomyces|Rep: MerA - Str... 33 6.7
UniRef50_A2Q979 Cluster: Contig An01c0240, complete genome; n=2;... 33 6.7
UniRef50_Q9KBT4 Cluster: 3-oxoacyl-(Acyl-carrier-protein) syntha... 32 8.8
UniRef50_Q4KCD8 Cluster: Nonribosomal peptide synthase; n=2; cel... 32 8.8
UniRef50_Q8RJY4 Cluster: StiC protein; n=1; Stigmatella aurantia... 32 8.8
UniRef50_Q8KUF6 Cluster: Polyketide synthase; n=2; cellular orga... 32 8.8
UniRef50_Q6V1M8 Cluster: Plm1; n=1; Streptomyces sp. HK803|Rep: ... 32 8.8
UniRef50_Q5VKQ3 Cluster: Type I PKS; n=4; cellular organisms|Rep... 32 8.8
UniRef50_Q54296 Cluster: Polyketide synthase; n=2; cellular orga... 32 8.8
UniRef50_Q53840 Cluster: Soraphen polyketide synthase B; n=2; ce... 32 8.8
UniRef50_Q27W72 Cluster: NigAIII; n=1; Streptomyces violaceusnig... 32 8.8
UniRef50_Q27W71 Cluster: NigAIV; n=2; Streptomyces violaceusnige... 32 8.8
UniRef50_Q27W64 Cluster: NigAX; n=1; Streptomyces violaceusniger... 32 8.8
UniRef50_Q1D3S9 Cluster: Polyketide synthase type I; n=3; Cystob... 32 8.8
UniRef50_Q11T86 Cluster: 3-oxoacyl-[acyl-carrier protein] syntha... 32 8.8
UniRef50_Q0R4G7 Cluster: 3-oxoacyl-(Acyl-carrier-protein) syntha... 32 8.8
UniRef50_A3Q280 Cluster: Beta-ketoacyl synthase; n=4; Actinomyce... 32 8.8
UniRef50_A1I9L7 Cluster: Polyketide synthase modules and related... 32 8.8
UniRef50_A0UJ74 Cluster: Beta-ketoacyl synthase; n=2; Bacteria|R... 32 8.8
UniRef50_A0T6U5 Cluster: Beta-ketoacyl synthase; n=9; Burkholder... 32 8.8
UniRef50_Q8ILS9 Cluster: Putative uncharacterized protein; n=1; ... 32 8.8
UniRef50_Q6RKI0 Cluster: Polyketide synthase; n=4; Pezizomycotin... 32 8.8
UniRef50_Q4P0A3 Cluster: Putative uncharacterized protein; n=2; ... 32 8.8
UniRef50_Q2U886 Cluster: Polyketide synthase modules and related... 32 8.8
UniRef50_Q5UWD6 Cluster: 3-ketoacyl-CoA thiolase; n=3; cellular ... 32 8.8
UniRef50_O29958 Cluster: 3-ketoacyl-CoA thiolase; n=13; Archaea|... 32 8.8
UniRef50_Q02251 Cluster: Mycocerosic acid synthase; n=45; Mycoba... 32 8.8
>UniRef50_Q56CY6 Cluster: Acetoacetyl-CoA thiolase; n=5; cellular
organisms|Rep: Acetoacetyl-CoA thiolase - Dendroctonus
jeffreyi (Jeffrey pine beetle)
Length = 398
Score = 270 bits (661), Expect = 2e-71
Identities = 121/179 (67%), Positives = 148/179 (82%)
Frame = +1
Query: 58 IEXAGIPKXXIKXVYIGNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIML 237
I+ AGIPK +K V++GNVC +GQAPA QA +FAGLP STICTT+NKVCASGMKSIML
Sbjct: 47 IKRAGIPKEEVKEVFLGNVCQGGVGQAPARQATLFAGLPTSTICTTINKVCASGMKSIML 106
Query: 238 AAQGLQTGAQDIILAGGMESMSNVPFYLKRGETSYGGMQLVDGIVFDGLTDVYNKFHMGN 417
AQ LQTG+Q++++AGGMESMSN P+Y+KRG+T YGG+QLVDG+V DGLTDVYNK HMGN
Sbjct: 107 GAQALQTGSQEVVVAGGMESMSNAPYYMKRGQTPYGGVQLVDGVVLDGLTDVYNKVHMGN 166
Query: 418 CAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPVPQKRGAPVIFAEXE 594
CAENTAKKL ITRQ QDE+ ++SY RSA A++ + F ELVPV VPQK+G + ++ E
Sbjct: 167 CAENTAKKLGITRQQQDEFGISSYLRSAQAWQNRVFDFELVPVSVPQKKGQDTVVSKDE 225
>UniRef50_P24752 Cluster: Acetyl-CoA acetyltransferase,
mitochondrial precursor; n=52; cellular organisms|Rep:
Acetyl-CoA acetyltransferase, mitochondrial precursor -
Homo sapiens (Human)
Length = 427
Score = 231 bits (564), Expect = 1e-59
Identities = 111/179 (62%), Positives = 133/179 (74%)
Frame = +1
Query: 58 IEXAGIPKXXIKXVYIGNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIML 237
IE AGIPK +K Y+GNV GQAP QAV+ AGLP ST CTT+NKVCASGMK+IM+
Sbjct: 76 IEKAGIPKEEVKEAYMGNVLQGGEGQAPTRQAVLGAGLPISTPCTTINKVCASGMKAIMM 135
Query: 238 AAQGLQTGAQDIILAGGMESMSNVPFYLKRGETSYGGMQLVDGIVFDGLTDVYNKFHMGN 417
A+Q L G QD+++AGGMESMSNVP+ + RG T YGG++L D IV DGLTDVYNK HMG+
Sbjct: 136 ASQSLMCGHQDVMVAGGMESMSNVPYVMNRGSTPYGGVKLEDLIVKDGLTDVYNKIHMGS 195
Query: 418 CAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPVPQKRGAPVIFAEXE 594
CAENTAKKL I R +QD YA+NSY RS AA+EA F +E++PV V K V+ E E
Sbjct: 196 CAENTAKKLNIARNEQDAYAINSYTRSKAAWEAGKFGNEVIPVTVTVKGQPDVVVKEDE 254
>UniRef50_Q0UU17 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 317
Score = 180 bits (437), Expect = 3e-44
Identities = 91/200 (45%), Positives = 117/200 (58%), Gaps = 2/200 (1%)
Frame = +1
Query: 1 GRFSXFXXXXXXXXXXXXXIEXAGIPKXXIKXVYIGNVCSANLGQAPAXQAVIFAGLPKS 180
G S +E AG+ ++ V++GNV SA LGQ PA Q I AGLP+S
Sbjct: 22 GSLSSLSAIQLGSHAIKAAVERAGLKPEDVEEVFVGNVLSAGLGQNPARQCAIGAGLPES 81
Query: 181 TICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPFYLK--RGETSYGGMQ 354
T+ TT+NKVCAS +KS++L AQ + TG DI++A G ESMSN P YL R +G
Sbjct: 82 TVSTTINKVCASSIKSLILGAQTIITGNADIVVAAGTESMSNTPHYLPNLRTGAKFGDQP 141
Query: 355 LVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDE 534
LVDG++ DGLTD Y K HMG E A R+ QDEY + SYK++ AA EA F E
Sbjct: 142 LVDGVLKDGLTDAYKKEHMGLQGEECADDHGFNREQQDEYCIRSYKKAIAATEAGWFTSE 201
Query: 535 LVPVPVPQKRGAPVIFAEXE 594
+ P+ VPQ RG P I + +
Sbjct: 202 IAPIEVPQGRGKPSITVDKD 221
>UniRef50_Q6L8K7 Cluster: Acetyl-CoA acetyltransferase; n=40;
cellular organisms|Rep: Acetyl-CoA acetyltransferase -
Yarrowia lipolytica (Candida lipolytica)
Length = 397
Score = 180 bits (437), Expect = 3e-44
Identities = 85/179 (47%), Positives = 118/179 (65%)
Frame = +1
Query: 58 IEXAGIPKXXIKXVYIGNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIML 237
++ + +P I G V +AN GQAPA Q VI G P+S TT+NKVC+SG+K++ L
Sbjct: 45 VQRSKVPADQIDEFLFGQVLTANSGQAPARQVVIKGGFPESVEATTINKVCSSGLKTVAL 104
Query: 238 AAQGLQTGAQDIILAGGMESMSNVPFYLKRGETSYGGMQLVDGIVFDGLTDVYNKFHMGN 417
AAQ ++ G +++I+AGGMESMSN P+Y RG +G +L D IV DGL D YN HMGN
Sbjct: 105 AAQAIKAGDRNVIVAGGMESMSNTPYYSGRG-LVFGNQKLEDSIVKDGLWDPYNNIHMGN 163
Query: 418 CAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPVPQKRGAPVIFAEXE 594
C ENT K+ ITR+ QDEYA+ SY+R+ + + AF DE+VPV + ++G + + E
Sbjct: 164 CCENTNKRDGITREQQDEYAIESYRRANESIKNGAFKDEIVPVEIKTRKGTVTVSEDEE 222
>UniRef50_UPI0001509D0E Cluster: acetyl-CoA acyltransferases family
protein; n=1; Tetrahymena thermophila SB210|Rep:
acetyl-CoA acyltransferases family protein - Tetrahymena
thermophila SB210
Length = 389
Score = 167 bits (407), Expect = 1e-40
Identities = 83/171 (48%), Positives = 111/171 (64%), Gaps = 3/171 (1%)
Frame = +1
Query: 58 IEXAGIPKXXIKXVYIGNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIML 237
++ + ++ V +GNVCSA +GQ PA QA + AGLP C +VNKVCASGMKS+M
Sbjct: 40 LQSINLDPKQVEEVILGNVCSAGVGQNPARQAALAAGLPIGVNCYSVNKVCASGMKSVMQ 99
Query: 238 AAQGLQTGAQDIILAGGMESMSNVPFYL---KRGETSYGGMQLVDGIVFDGLTDVYNKFH 408
A+Q +Q G D+I+ GG ESMSNVPFY+ ++G+ +G LVDG FDGLT+ Y+
Sbjct: 100 ASQTIQLGQADVIICGGFESMSNVPFYVTNHRKGQL-FGNQTLVDGAAFDGLTNFYDNKA 158
Query: 409 MGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPVPQK 561
MG CAE TA L+I R+ DEY V SY+R A + F +++VPV V K
Sbjct: 159 MGFCAEKTAADLKIDRKQNDEYCVESYERVLKALKTPEFKNDIVPVTVQNK 209
>UniRef50_P14611 Cluster: Acetyl-CoA acetyltransferase; n=43;
Bacteria|Rep: Acetyl-CoA acetyltransferase - Ralstonia
eutropha (strain ATCC 17699 / H16 / DSM 428 / Stanier
337)(Cupriavidus necator (strain ATCC 17699 / H16 / DSM
428 / Stanier337))
Length = 393
Score = 166 bits (404), Expect = 3e-40
Identities = 83/181 (45%), Positives = 114/181 (62%), Gaps = 2/181 (1%)
Frame = +1
Query: 58 IEXAGIPKXXIKXVYIGNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIML 237
+E AG+ + V +G V +A GQ PA QA I AGLP T+NKVC SG+K++ML
Sbjct: 38 LERAGVKPEQVSEVIMGQVLTAGSGQNPARQAAIKAGLPAMVPAMTINKVCGSGLKAVML 97
Query: 238 AAQGLQTGAQDIILAGGMESMSNVPFYLKRGETSY--GGMQLVDGIVFDGLTDVYNKFHM 411
AA + G +I++AGG E+MS P L + G +LVD ++ DGL DVYN++HM
Sbjct: 98 AANAIMAGDAEIVVAGGQENMSAAPHVLPGSRDGFRMGDAKLVDTMIVDGLWDVYNQYHM 157
Query: 412 GNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPVPQKRGAPVIFAEX 591
G AEN AK+ ITR+ QDE+AV S ++ AA +A F +E+VPV +PQ++G PV F
Sbjct: 158 GITAENVAKEYGITREAQDEFAVGSQNKAEAAQKAGKFDEEIVPVLIPQRKGDPVAFKTD 217
Query: 592 E 594
E
Sbjct: 218 E 218
>UniRef50_Q8RC88 Cluster: Acetyl-CoA acetyltransferases; n=2;
Bacteria|Rep: Acetyl-CoA acetyltransferases -
Thermoanaerobacter tengcongensis
Length = 394
Score = 165 bits (400), Expect = 9e-40
Identities = 78/183 (42%), Positives = 119/183 (65%), Gaps = 4/183 (2%)
Frame = +1
Query: 58 IEXAGIPKXXIKXVYIGNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIML 237
++ A + + V++G + A LGQ PA Q+ + AG+P TT+N VC SG++++ +
Sbjct: 38 LKRAKVAPEQVDEVFMGIILQAGLGQNPARQSAVKAGIPVEVPATTINMVCGSGLRTVAM 97
Query: 238 AAQGLQTGAQDIILAGGMESMSNVPFYLKRGETSYG----GMQLVDGIVFDGLTDVYNKF 405
AAQ + G DI++AGGMESMS P+ L+ Y +LVD +V+DGL DV+N++
Sbjct: 98 AAQAVMLGDADIVVAGGMESMSRAPYLLRDARWGYRMNMPSGELVDEMVYDGLWDVFNQY 157
Query: 406 HMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPVPQKRGAPVIFA 585
HMG AEN A++ +I+RQ+QDE+A+ S + AA +A F +E+VPVP+PQK+G P+ F
Sbjct: 158 HMGITAENIAERYKISRQEQDEFALRSQNLAEAAIKAGKFEEEIVPVPIPQKKGDPIEFK 217
Query: 586 EXE 594
E
Sbjct: 218 VDE 220
>UniRef50_A4G2P1 Cluster: Acetyl-CoA acetyltransferase; n=10;
Bacteria|Rep: Acetyl-CoA acetyltransferase -
Herminiimonas arsenicoxydans
Length = 391
Score = 157 bits (380), Expect = 2e-37
Identities = 80/172 (46%), Positives = 107/172 (62%), Gaps = 2/172 (1%)
Frame = +1
Query: 70 GIPKXXIKXVYIGNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQG 249
GI I V +G V +A GQ PA QA I GLP T+NKVC SG+K+ LAAQ
Sbjct: 42 GIAADAISEVILGQVLTAGCGQNPARQASIRGGLPDMVPAFTINKVCGSGLKATHLAAQA 101
Query: 250 LQTGAQDIILAGGMESMSNVPFYLKRGETSY--GGMQLVDGIVFDGLTDVYNKFHMGNCA 423
+Q G II+AGG E+MS P L+ G +LVD ++ DGL DVYN++HMG A
Sbjct: 102 IQCGDAHIIIAGGQENMSASPHVLQNSREGIRMGDGKLVDTMIIDGLWDVYNQYHMGTTA 161
Query: 424 ENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPVPQKRGAPVI 579
EN AKK I+RQ+QDE+A+ S ++ AA A F DE++P+ +P K+GA ++
Sbjct: 162 ENIAKKFGISRQEQDEFALASQHKAEAAQNAGKFKDEIIPLEIPGKKGAVIV 213
>UniRef50_Q87GW1 Cluster: Acetyl-CoA acetyltransferase; n=41;
Bacteria|Rep: Acetyl-CoA acetyltransferase - Vibrio
parahaemolyticus
Length = 402
Score = 153 bits (372), Expect = 2e-36
Identities = 77/172 (44%), Positives = 109/172 (63%), Gaps = 3/172 (1%)
Frame = +1
Query: 58 IEXAGIPKXXIKXVYIGNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIML 237
+E A + + V +GNV A G QA +FAG+P+S VN VC SGMK++M
Sbjct: 38 LEAAKLAGDKVDEVIVGNVVGAGQGMGVGRQAALFAGIPESVPAYGVNMVCGSGMKTVMD 97
Query: 238 AAQGLQTGAQDIILAGGMESMSNVPFYLK---RGETSYGGMQLVDGIVFDGLTDVYNKFH 408
A +++G +I++A G+E MS +PF R G ++L D +V DGLTDVYN++H
Sbjct: 98 AVSHIRSGDAEIVVAAGVEVMSQIPFAAPSSIRDGNKMGNLELKDLLVADGLTDVYNQYH 157
Query: 409 MGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPVPQKR 564
MG AEN AK++ +TRQ QDEYA++S +++ AA EA F DE+VPV V Q+R
Sbjct: 158 MGVTAENVAKEIGLTRQQQDEYALSSQQKAVAAIEAGKFKDEIVPVEVQQRR 209
>UniRef50_A4SMV2 Cluster: Acetyl-CoA acetyltransferase; n=1;
Aeromonas salmonicida subsp. salmonicida A449|Rep:
Acetyl-CoA acetyltransferase - Aeromonas salmonicida
(strain A449)
Length = 334
Score = 151 bits (367), Expect = 9e-36
Identities = 82/181 (45%), Positives = 111/181 (61%), Gaps = 2/181 (1%)
Frame = +1
Query: 58 IEXAGIPKXXIKXVYIGNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIML 237
I AG+ I Y+GNV SA +GQAPA QAV+ AGLP+S CTTVNKVC SGMK++ML
Sbjct: 37 IAQAGLKGEQIDEAYMGNVLSAGVGQAPARQAVLKAGLPESVPCTTVNKVCGSGMKAVML 96
Query: 238 AAQGLQTGAQDIILAGGMESMSNVPFYLKRGETSY--GGMQLVDGIVFDGLTDVYNKFHM 411
AA L+ G DI++AGGMESMS P+ L + + + G ++D + DGL D Y M
Sbjct: 97 AADSLRLGDTDIVIAGGMESMSRAPYLLDKARSGFRMGHQSVLDHMFLDGLQDAYEGQLM 156
Query: 412 GNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPVPQKRGAPVIFAEX 591
G+ A+ +A + + R D D +A+ S R+ AA ++ AF EL V V G ++ AE
Sbjct: 157 GHYAQLSADRAGLARSDMDAFAIASLTRALAAQQSGAFKAELAQVTV----GDTLLLAED 212
Query: 592 E 594
E
Sbjct: 213 E 213
>UniRef50_P41338 Cluster: Acetyl-CoA acetyltransferase; n=104;
root|Rep: Acetyl-CoA acetyltransferase - Saccharomyces
cerevisiae (Baker's yeast)
Length = 398
Score = 151 bits (365), Expect = 2e-35
Identities = 74/161 (45%), Positives = 102/161 (63%), Gaps = 2/161 (1%)
Frame = +1
Query: 97 VYIGNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDII 276
+ GNV SANLGQAPA Q + AGL + +TVNKVCAS MK+I+L AQ ++ G D++
Sbjct: 54 IIFGNVLSANLGQAPARQVALAAGLSNHIVASTVNKVCASAMKAIILGAQSIKCGNADVV 113
Query: 277 LAGGMESMSNVPFYL--KRGETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQI 450
+AGG ESM+N P+Y+ R +G LVDG+ DGL D Y+ MG AE A+ I
Sbjct: 114 VAGGCESMTNAPYYMPAARAGAKFGQTVLVDGVERDGLNDAYDGLAMGVHAEKCARDWDI 173
Query: 451 TRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPVPQKRGAP 573
TR+ QD +A+ SY++S + + F +E+VPV + RG P
Sbjct: 174 TREQQDNFAIESYQKSQKSQKEGKFDNEIVPVTIKGFRGKP 214
>UniRef50_Q1GV21 Cluster: Acetyl-CoA C-acetyltransferase; n=66;
Bacteria|Rep: Acetyl-CoA C-acetyltransferase -
Sphingopyxis alaskensis (Sphingomonas alaskensis)
Length = 395
Score = 150 bits (364), Expect = 2e-35
Identities = 81/196 (41%), Positives = 111/196 (56%), Gaps = 3/196 (1%)
Frame = +1
Query: 1 GRFSXFXXXXXXXXXXXXXIEXAGIPKXXIKXVYIGNVCSANLGQAPAXQAVIFAGLPKS 180
G S +E AG+ I+ +Y+G V A LGQAPA QA I AGLPKS
Sbjct: 22 GSLSDASATDLGATAVKAAVERAGVSGDDIERIYMGCVLPAGLGQAPARQAAIKAGLPKS 81
Query: 181 TICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPFYLK--RGETSYGGMQ 354
TTVNKVC SGM+++++ A+ L G+ ++I+AGGMESM+N P+ LK R G
Sbjct: 82 VQATTVNKVCGSGMQTVIMGAEALAAGSVELIVAGGMESMTNAPYLLKKHRSGARIGHDT 141
Query: 355 LVDGIVFDGLTDVYNKFH-MGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVD 531
D + DGL D Y+ MG A++TA Q++RQ D+Y + S R+ AA AFV
Sbjct: 142 AYDHMFLDGLEDAYDAGRAMGTFAQDTADAYQLSRQAMDDYTLTSLSRAKAAIAEGAFVA 201
Query: 532 ELVPVPVPQKRGAPVI 579
E+ PV + +RG V+
Sbjct: 202 EIAPVTISGRRGDVVV 217
>UniRef50_Q9K6C8 Cluster: Acetyl-CoA acetyltransferase; n=6;
Firmicutes|Rep: Acetyl-CoA acetyltransferase - Bacillus
halodurans
Length = 392
Score = 148 bits (358), Expect = 1e-34
Identities = 71/168 (42%), Positives = 108/168 (64%), Gaps = 2/168 (1%)
Frame = +1
Query: 88 IKXVYIGNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQ 267
+ + +GNV GQ P+ QA+ A LP T+NKVCASGM+S+ LA Q +++G+
Sbjct: 47 VDDLIMGNVLQGGQGQLPSRQALKEADLPWDVRTETINKVCASGMRSVTLADQLIRSGSS 106
Query: 268 DIILAGGMESMSNVPFYLKRGE--TSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKK 441
+++AGGMESMS P+Y+ + G ++++DG+VFDGLT + HMG TA +
Sbjct: 107 KVVVAGGMESMSQAPYYVPKARWGARMGHVEMIDGMVFDGLTCAFTGVHMGTYGNGTAHE 166
Query: 442 LQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPVPQKRGAPVIFA 585
L I+R+ QDE+A S++R+ AA A +E+VPV VPQ++G P++ A
Sbjct: 167 LAISREAQDEWAYRSHQRAIAAIGAGRLEEEIVPVEVPQRKGEPLLVA 214
>UniRef50_P54810 Cluster: Acetyl-CoA acetyltransferase; n=122;
Bacteria|Rep: Acetyl-CoA acetyltransferase - Paracoccus
denitrificans
Length = 391
Score = 145 bits (352), Expect = 6e-34
Identities = 73/179 (40%), Positives = 111/179 (62%), Gaps = 2/179 (1%)
Frame = +1
Query: 58 IEXAGIPKXXIKXVYIGNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIML 237
+E AGI + +G V +A GQ PA QA I GLP+ + +N+VC SG++++ L
Sbjct: 38 VERAGIDPSEVSETILGQVLTAAQGQNPARQAHIKVGLPRESAAWVINQVCGSGLRTVAL 97
Query: 238 AAQGLQTGAQDIILAGGMESMSNVPF--YLKRGETSYGGMQLVDGIVFDGLTDVYNKFHM 411
AAQ + G I++AGG ESMS P Y+ G+ G M+++D ++ DGL D +N +HM
Sbjct: 98 AAQQVLLGDARIVVAGGQESMSLAPHAAYIAPGQ-KMGDMKMLDTMIKDGLWDAFNDYHM 156
Query: 412 GNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPVPQKRGAPVIFAE 588
G AEN A K +I+R +QD++AV S ++ AA +A F DE+VPV + ++G V+ A+
Sbjct: 157 GTTAENVAGKWEISRAEQDQFAVASQNKAEAAQKAGKFADEIVPVTIKSRKGETVVDAD 215
>UniRef50_Q67RA4 Cluster: Acetyl-CoA acetyltransferase; n=5;
Bacteria|Rep: Acetyl-CoA acetyltransferase -
Symbiobacterium thermophilum
Length = 392
Score = 144 bits (348), Expect = 2e-33
Identities = 78/198 (39%), Positives = 110/198 (55%), Gaps = 2/198 (1%)
Frame = +1
Query: 1 GRFSXFXXXXXXXXXXXXXIEXAGIPKXXIKXVYIGNVCSANLGQAPAXQAVIFAGLPKS 180
G S + AGI + V IG V A GQ PA A + AG+P +
Sbjct: 19 GALSTVKSYELGAAAIAEALRRAGIRGEQVDEVIIGQVLEAGEGQHPARIASLKAGIPYT 78
Query: 181 TICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPFYLKRGETSY--GGMQ 354
T VNKVC SG+K++ LAAQ + G D+++AGG ESMS P+ + R Y G Q
Sbjct: 79 VPVTGVNKVCGSGLKAVALAAQAIMLGDADVVVAGGQESMSGAPYLVPRARFGYRMGHGQ 138
Query: 355 LVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDE 534
LVD ++ D LT + HMG AEN A++ I+R+DQD +A S +++ AA +A F +E
Sbjct: 139 LVDSMIADALTCGWEHVHMGLTAENIAEQFGISREDQDAFAAASQQKAEAAIKAGRFREE 198
Query: 535 LVPVPVPQKRGAPVIFAE 588
+VPV VP ++G V+ A+
Sbjct: 199 IVPVTVPGRKGDTVVDAD 216
>UniRef50_O29070 Cluster: 3-ketoacyl-CoA thiolase; n=2; cellular
organisms|Rep: 3-ketoacyl-CoA thiolase - Archaeoglobus
fulgidus
Length = 424
Score = 138 bits (335), Expect = 7e-32
Identities = 73/169 (43%), Positives = 102/169 (60%), Gaps = 5/169 (2%)
Frame = +1
Query: 88 IKXVYIGNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQ 267
I V +GNV A GQ PA QA I AG+PK TVNKVC SG+K+I LA ++ G
Sbjct: 77 IDEVIMGNVLQAAQGQNPARQASILAGIPKEIPAYTVNKVCGSGLKAIALAYHAVKAGDA 136
Query: 268 DIILAGGMESMSNVPFYLKRGETSY-----GGMQLVDGIVFDGLTDVYNKFHMGNCAENT 432
I+AGGMESMSN P+ L + Y +++D +V+DGL + + +HMG AEN
Sbjct: 137 KAIIAGGMESMSNAPYALPKARWGYRMSVTAKDEILDLMVYDGLWEKFYGYHMGMTAENI 196
Query: 433 AKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPVPQKRGAPVI 579
++ I+R++QD+ A S+ R+ A + F E+VPV V QK+GA V+
Sbjct: 197 VERYGISREEQDQLAYESHMRAVRAIDEGKFAQEIVPVEVKQKKGAVVV 245
>UniRef50_A1SHM4 Cluster: Acetyl-CoA acetyltransferases; n=8;
Bacteria|Rep: Acetyl-CoA acetyltransferases -
Nocardioides sp. (strain BAA-499 / JS614)
Length = 396
Score = 138 bits (334), Expect = 9e-32
Identities = 71/183 (38%), Positives = 109/183 (59%), Gaps = 4/183 (2%)
Frame = +1
Query: 58 IEXAGIPKXXIKXVYIGNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIML 237
+E AG+ ++ V +G+V A GQ A QA + G+P + T+NKVC SGM +I L
Sbjct: 38 LEKAGVTGDQVEYVIMGHVIQAGAGQITARQASVKGGIPMNVPAITINKVCLSGMNAIAL 97
Query: 238 AAQGLQTGAQDIILAGGMESMSNVPFYLKRGET--SYGGMQLVDGIVFDGLTDVYNKFHM 411
A Q ++ G +I++AGGMESM+ P L + YG LVD + +D L D + M
Sbjct: 98 ADQLIRAGEHEIVVAGGMESMTQAPHLLPKSREGFKYGDTALVDSMAYDALYDQFTDQPM 157
Query: 412 GNCAE--NTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPVPQKRGAPVIFA 585
G E NT + ++TR++QD ++ S++ +AAA++ F DE+VPV +PQ++G PV+ A
Sbjct: 158 GTLTEACNTGAR-ELTREEQDAFSARSHQLAAAAWKNGVFDDEVVPVEIPQRKGDPVVIA 216
Query: 586 EXE 594
E
Sbjct: 217 NDE 219
>UniRef50_A0NJ40 Cluster: Acetyl-CoA C-acetyltransferase-like
protein; n=2; Oenococcus oeni|Rep: Acetyl-CoA
C-acetyltransferase-like protein - Oenococcus oeni ATCC
BAA-1163
Length = 386
Score = 137 bits (331), Expect = 2e-31
Identities = 75/174 (43%), Positives = 102/174 (58%), Gaps = 2/174 (1%)
Frame = +1
Query: 58 IEXAGIPKXXIKXVYIGNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIML 237
++ + I I +Y+GNV A +GQ PA QA AG+P S TT+N VC SG+ SI L
Sbjct: 40 LKRSEISAEEIDEIYMGNVIQAGVGQNPARQAARLAGIPFSIPSTTINDVCGSGLHSINL 99
Query: 238 AAQGLQTGAQDIILAGGMESMSNVPFYLKRGETSY--GGMQLVDGIVFDGLTDVYNKFHM 411
AA+ + G DII+AGGMESMSN PF LK + G ++ D ++ D L D FHM
Sbjct: 100 AAKLIAGGFDDIIVAGGMESMSNAPFLLKNHRFGHKLGNEKIDDTLLRDALIDPIGNFHM 159
Query: 412 GNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPVPQKRGAP 573
G AEN A++ I+RQ D YA+ S+ R+ A + F DE+V V ++ AP
Sbjct: 160 GITAENIAERYSISRQSMDRYALESHSRAVRAEKKGLFNDEIVAVDQVKQDQAP 213
>UniRef50_A1WCB0 Cluster: Acetyl-CoA acetyltransferases; n=36;
Proteobacteria|Rep: Acetyl-CoA acetyltransferases -
Acidovorax sp. (strain JS42)
Length = 396
Score = 135 bits (327), Expect = 6e-31
Identities = 70/173 (40%), Positives = 103/173 (59%), Gaps = 3/173 (1%)
Frame = +1
Query: 58 IEXAGIPKXXIKXVYIGNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIML 237
+E AGI + V GN A GQAPA QA GLP+ST T++K+C +GM++ +L
Sbjct: 42 VERAGIAPEKVDEVLFGNCLMAGQGQAPARQAGFKGGLPQSTGAVTLSKMCGAGMEATIL 101
Query: 238 AAQGLQTGAQDIILAGGMESMSNVPFYLKRGETSY--GGMQLVDGIVFDGLTDVYNKFH- 408
A L G++D++++GGMESM+N P+ LK+G Y G ++ D ++ DGL D Y
Sbjct: 102 AHDQLIAGSRDVMVSGGMESMTNAPYLLKKGRGGYRMGHDKVYDHMMLDGLEDAYEAGRS 161
Query: 409 MGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPVPQKRG 567
MG E+ A K TR+ QD +A+ S KR+ A ++ AF E+ PV V ++G
Sbjct: 162 MGTFGEDCAAKYSFTREQQDAFAIESVKRAQQATQSGAFATEITPVTVKTRKG 214
>UniRef50_Q577L1 Cluster: PhbA-2, acetyl-CoA acetyltransferase;
n=72; Proteobacteria|Rep: PhbA-2, acetyl-CoA
acetyltransferase - Brucella abortus
Length = 399
Score = 134 bits (325), Expect = 1e-30
Identities = 76/191 (39%), Positives = 105/191 (54%), Gaps = 3/191 (1%)
Frame = +1
Query: 1 GRFSXFXXXXXXXXXXXXXIEXAGIPKXXIKXVYIGNVCSANLGQAPAXQAVIFAGLPKS 180
G F+ + AG+ ++ V +G V A GQAPA QA + AGLP
Sbjct: 22 GDFTNAQATDLGASAIGGALAGAGLAPEAVEEVIMGCVLPAGQGQAPARQASLKAGLPLG 81
Query: 181 TICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPFYLKRGETSY--GGMQ 354
T TTVNK+C SGMK+ MLA + G+ D+I+AGGMESM+N P+ L + Y G Q
Sbjct: 82 TGATTVNKMCGSGMKAAMLAHDLILAGSADVIVAGGMESMTNAPYLLPKARGGYRMGHGQ 141
Query: 355 LVDGIVFDGLTDVYNKFH-MGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVD 531
++D + DGL D Y+K MG AE+ A+ Q TR+ QD +A++S R+ A + F
Sbjct: 142 VLDHMFLDGLEDAYDKGRLMGTFAEDCAEAYQFTREAQDAFAISSLTRAQNAIKDGLFAA 201
Query: 532 ELVPVPVPQKR 564
E+ PV V R
Sbjct: 202 EITPVKVKSGR 212
>UniRef50_Q9BWD1 Cluster: Acetyl-CoA acetyltransferase, cytosolic;
n=295; cellular organisms|Rep: Acetyl-CoA
acetyltransferase, cytosolic - Homo sapiens (Human)
Length = 397
Score = 134 bits (323), Expect = 2e-30
Identities = 71/172 (41%), Positives = 101/172 (58%), Gaps = 2/172 (1%)
Frame = +1
Query: 58 IEXAGIPKXXIKXVYIGNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIML 237
++ A + + V G+V +A GQ P QA + AG+P S + +C SG+K++ L
Sbjct: 42 LKRATVAPEDVSEVIFGHVLAAGCGQNPVRQASVGAGIPYSVPAWSCQMICGSGLKAVCL 101
Query: 238 AAQGLQTGAQDIILAGGMESMSNVPF--YLKRGETSYGGMQLVDGIVFDGLTDVYNKFHM 411
A Q + G I++AGGME+MS P YL+ G G M L D I+ DGLTD ++ HM
Sbjct: 102 AVQSIGIGDSSIVVAGGMENMSKAPHLAYLRTG-VKIGEMPLTDSILCDGLTDAFHNCHM 160
Query: 412 GNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPVPQKRG 567
G AEN AKK Q++R+DQD+ AV S R+ A +A F E+VPV V ++G
Sbjct: 161 GITAENVAKKWQVSREDQDKVAVLSQNRTENAQKAGHFDKEIVPVLVSTRKG 212
>UniRef50_Q8CAY6 Cluster: Acetyl-CoA acetyltransferase, cytosolic;
n=40; cellular organisms|Rep: Acetyl-CoA
acetyltransferase, cytosolic - Mus musculus (Mouse)
Length = 397
Score = 131 bits (316), Expect = 1e-29
Identities = 69/172 (40%), Positives = 102/172 (59%), Gaps = 2/172 (1%)
Frame = +1
Query: 58 IEXAGIPKXXIKXVYIGNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIML 237
++ A + + V G+V +A GQ P QA + AG+P S + +C SG+K++ L
Sbjct: 42 LQRAKVAPEEVSEVIFGHVLTAGCGQNPTRQASVGAGIPYSVPAWSCQMICGSGLKAVCL 101
Query: 238 AAQGLQTGAQDIILAGGMESMSNVPF--YLKRGETSYGGMQLVDGIVFDGLTDVYNKFHM 411
AAQ + G I++AGGME+MS P +L+ G G + L D I+ DGLTD ++ +HM
Sbjct: 102 AAQSIAMGDSTIVVAGGMENMSKAPHLTHLRTG-VRMGEVPLADSILCDGLTDAFHNYHM 160
Query: 412 GNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPVPQKRG 567
G AEN AKK Q++R+ QD+ AV S R+ A +A F E+VPV V ++G
Sbjct: 161 GITAENVAKKWQVSREAQDKVAVLSQNRAEHAQKAGHFDKEIVPVLVSSRKG 212
>UniRef50_P45855 Cluster: Acetyl-CoA acetyltransferase; n=32;
Bacteria|Rep: Acetyl-CoA acetyltransferase - Bacillus
subtilis
Length = 393
Score = 129 bits (312), Expect = 4e-29
Identities = 68/181 (37%), Positives = 108/181 (59%), Gaps = 2/181 (1%)
Frame = +1
Query: 58 IEXAGIPKXXIKXVYIGNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIML 237
++ AG+ ++ +G V A GQ P+ QA AG+P S T+NKVCASG++++ L
Sbjct: 38 LQQAGVSGDDVEGNVMGMVVQAGSGQIPSRQAARLAGMPWSVPSETLNKVCASGLRAVTL 97
Query: 238 AAQGLQTGAQDIILAGGMESMSNVPFYLKRGE--TSYGGMQLVDGIVFDGLTDVYNKFHM 411
Q ++ DI++AGGMESMSN+P+ + G G +L D +V+DGLT +++ HM
Sbjct: 98 CDQMIRAQDADILVAGGMESMSNIPYAVPAGRWGARMGDGELRDLMVYDGLTCAFDEVHM 157
Query: 412 GNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPVPQKRGAPVIFAEX 591
AK+ I+R++QDE+A+ S+ R+A A + F DE+VPV ++G P + +
Sbjct: 158 AVHGNTAAKEYAISRREQDEWALRSHARAAKAADEGKFQDEIVPVNWIGRKGKPNVVDKD 217
Query: 592 E 594
E
Sbjct: 218 E 218
>UniRef50_A2DM80 Cluster: Acetyl-CoA acyltransferases family
protein; n=2; Trichomonas vaginalis G3|Rep: Acetyl-CoA
acyltransferases family protein - Trichomonas vaginalis
G3
Length = 387
Score = 128 bits (308), Expect = 1e-28
Identities = 64/165 (38%), Positives = 94/165 (56%), Gaps = 3/165 (1%)
Frame = +1
Query: 61 EXAGIPKXXIKXVYIGNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIMLA 240
E +GI +YIGNV SA +GQ PA QA + AG P +T CT +NKVC S MK++ L
Sbjct: 39 EKSGIAIEQFNSIYIGNVVSAGIGQNPAKQAALAAGFPVTTPCTLINKVCCSSMKALQLG 98
Query: 241 AQGLQTGAQDIILAGGMESMSNVPFYLKRGETSY--GGMQLVDGIVFDGLTDV-YNKFHM 411
++ G ++ GG E+MS P L+ Y G +D ++ DGL D YN+ M
Sbjct: 99 VLEIKAGDSQAVMIGGFENMSRCPHLLQNSRNGYRLGNFSAIDSLINDGLWDAKYNQM-M 157
Query: 412 GNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPV 546
G + +K I+R+DQD +A+ S+ R+ A+E AF ++ VP+
Sbjct: 158 GQLVDVLNEKQGISREDQDRFAIQSFDRATKAWEEHAFDEQNVPI 202
>UniRef50_Q8D6N4 Cluster: Acetyl-CoA acetyltransferase; n=14;
Vibrionaceae|Rep: Acetyl-CoA acetyltransferase - Vibrio
vulnificus
Length = 405
Score = 126 bits (304), Expect = 4e-28
Identities = 68/165 (41%), Positives = 92/165 (55%), Gaps = 2/165 (1%)
Frame = +1
Query: 58 IEXAGIPKXXIKXVYIGNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIML 237
++ + + VY+G V A GQAPA QA + A L ST CTTVNKVC SGMK++ML
Sbjct: 39 MDAVSLSAQQVDEVYMGCVLPAGCGQAPARQAALKAELGYSTPCTTVNKVCGSGMKAVML 98
Query: 238 AAQGLQTGAQDIILAGGMESMSNVPFYLK--RGETSYGGMQLVDGIVFDGLTDVYNKFHM 411
A L+ G + ++AGGMESM+N P+ LK R G D + DGL D Y M
Sbjct: 99 AYDQLKAGDKCCMIAGGMESMTNAPYLLKESRSGMRMGHKTTFDHMFLDGLQDAYEGHLM 158
Query: 412 GNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPV 546
G A+ A KL TR+ D +A+ S +R+ A F +E+ P+
Sbjct: 159 GVYAQQIADKLNYTREQMDTWAIQSAQRATQAQHEAQFKEEITPI 203
>UniRef50_Q6KYW2 Cluster: Acetyl-CoA acetyltransferase; n=4;
Thermoplasmatales|Rep: Acetyl-CoA acetyltransferase -
Picrophilus torridus
Length = 388
Score = 123 bits (297), Expect = 3e-27
Identities = 70/186 (37%), Positives = 99/186 (53%), Gaps = 6/186 (3%)
Frame = +1
Query: 7 FSXFXXXXXXXXXXXXXIEXAGIPKXXIKXVYIGNVCSANLGQAPAXQAVIFAGLPKSTI 186
FS I+ A + ++ V +GNV +GQ PA QA AGLP
Sbjct: 21 FSKIKATELGGKAIRAAIDDAKLDPALVQEVIMGNVIEGGVGQNPAGQAAYHAGLPFGVT 80
Query: 187 CTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPFYLKR------GETSYGG 348
TVN VCASGM ++ AA+ + G +D+I+AGGME+MS P L + Y
Sbjct: 81 KYTVNVVCASGMLAVESAAREIMLGERDLIVAGGMENMSMSPLLLSSEFRWGPKQLLYKN 140
Query: 349 MQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFV 528
M++ D ++ DGL D HMG AE +A+K +TR+D D Y+V S +R+ A E+ F
Sbjct: 141 MKIEDSMLVDGLIDAMYYEHMGVSAERSARKYNLTREDADSYSVQSQERAIRATESGEFR 200
Query: 529 DELVPV 546
+E+VPV
Sbjct: 201 NEIVPV 206
>UniRef50_Q5UX35 Cluster: Acetyl-coA acetyltransferase; n=1;
Haloarcula marismortui|Rep: Acetyl-coA acetyltransferase
- Haloarcula marismortui (Halobacterium marismortui)
Length = 387
Score = 123 bits (297), Expect = 3e-27
Identities = 64/184 (34%), Positives = 95/184 (51%), Gaps = 2/184 (1%)
Frame = +1
Query: 1 GRFSXFXXXXXXXXXXXXXIEXAGIPKXXIKXVYIGNVCSANLGQAPAXQAVIFAGLPKS 180
GR + + + + + V +GN A +GQ PA Q V+ + LP
Sbjct: 19 GRLTDRSAIALGSAAVEGLLNRTSVDEDSVDWVGLGNAVQAGVGQVPARQVVVESSLPDD 78
Query: 181 TICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPFYL--KRGETSYGGMQ 354
TT+N+ SG+++I AA ++ G + LAGGMESMSN P+ + RG +G +
Sbjct: 79 VAATTLNEASGSGLRAITTAADRIEAGRASVCLAGGMESMSNAPYLVPDMRGGRRHGNSE 138
Query: 355 LVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDE 534
LVD +++D L D HMG E A + I+R+ QDEYA S R+ A ++ F +E
Sbjct: 139 LVDAMIWDSLWDKQYDAHMGTLTEELAAEHDISREAQDEYARRSNHRAGEAIQSGQFTEE 198
Query: 535 LVPV 546
LVPV
Sbjct: 199 LVPV 202
>UniRef50_Q2GA69 Cluster: Acetyl-CoA C-acetyltransferase; n=2;
Alphaproteobacteria|Rep: Acetyl-CoA C-acetyltransferase
- Novosphingobium aromaticivorans (strain DSM 12444)
Length = 392
Score = 121 bits (292), Expect = 1e-26
Identities = 71/182 (39%), Positives = 102/182 (56%), Gaps = 3/182 (1%)
Frame = +1
Query: 58 IEXAGIPKXXIKXVYIGNVCSANLGQAPAXQ-AVIFAGLPKSTICTTVNKVCASGMKSIM 234
I AGI ++ V IG V A + A + AG+P VN++C SG+++I+
Sbjct: 38 IARAGIAPDKVQNVVIGTVVPTQPKDAYVSRVAAVNAGIPIEAPAMNVNRLCGSGLQAIV 97
Query: 235 LAAQGLQTGAQDIILAGGMESMSNVPFYL--KRGETSYGGMQLVDGIVFDGLTDVYNKFH 408
AAQG+ G QDI + GG ESMSN P + R G L+D ++ L D + H
Sbjct: 98 SAAQGIALGEQDIAIGGGAESMSNAPHMVLTARNGQKMGDQVLMDAML-GALHDPFEGIH 156
Query: 409 MGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPVPQKRGAPVIFAE 588
MG AEN A++ QITR++QD AV S+KR+AAA A F +++VPV + ++G V+F
Sbjct: 157 MGVTAENVAERCQITREEQDSLAVESHKRAAAAIAAGYFKEQIVPVEIKTRKGV-VVFDT 215
Query: 589 XE 594
E
Sbjct: 216 DE 217
>UniRef50_Q6P3T4 Cluster: ACAT1 protein; n=3; Coelomata|Rep: ACAT1
protein - Homo sapiens (Human)
Length = 289
Score = 121 bits (291), Expect = 1e-26
Identities = 70/165 (42%), Positives = 95/165 (57%), Gaps = 6/165 (3%)
Frame = +1
Query: 118 SANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMES 297
+ LG A+ AG+PK +V + M +++ +G Q + +L G +
Sbjct: 64 ATKLGSIAIQGAIEKAGIPKE-------EVKEAYMGNVLQGGEG-QAPTRQAVLGAGCDG 115
Query: 298 MS------NVPFYLKRGETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQ 459
+VP+ + RG T YGG++L D IV DGLTDVYNK HMG+CAENTAKKL I R
Sbjct: 116 GRWDGEHVHVPYVMNRGSTPYGGVKLEDLIVKDGLTDVYNKIHMGSCAENTAKKLNIARN 175
Query: 460 DQDEYAVNSYKRSAAAYEAKAFVDELVPVPVPQKRGAPVIFAEXE 594
+QD YA+NSY RS AA+EA F +E++PV V K V+ E E
Sbjct: 176 EQDAYAINSYTRSKAAWEAGKFGNEVIPVTVTVKGQPDVVVKEDE 220
Score = 45.2 bits (102), Expect = 0.001
Identities = 21/37 (56%), Positives = 24/37 (64%)
Frame = +1
Query: 58 IEXAGIPKXXIKXVYIGNVCSANLGQAPAXQAVIFAG 168
IE AGIPK +K Y+GNV GQAP QAV+ AG
Sbjct: 76 IEKAGIPKEEVKEAYMGNVLQGGEGQAPTRQAVLGAG 112
>UniRef50_Q74IF9 Cluster: Acetyl-CoA acetyltransferase; n=5;
Lactobacillus|Rep: Acetyl-CoA acetyltransferase -
Lactobacillus johnsonii
Length = 388
Score = 120 bits (288), Expect = 3e-26
Identities = 60/158 (37%), Positives = 90/158 (56%)
Frame = +1
Query: 73 IPKXXIKXVYIGNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGL 252
+P+ I + +GNV SA LGQ A Q + +GLP+S + T+V+ VC S +K++ A +
Sbjct: 44 VPQDKIDSILVGNVLSAGLGQNVARQIALKSGLPESVVGTSVDDVCGSSLKALRFAQGQM 103
Query: 253 QTGAQDIILAGGMESMSNVPFYLKRGETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENT 432
G I + GG ESM+N P L + + D ++ DG+ D Y++ MG AEN
Sbjct: 104 LLGDSQIAIVGGAESMTNAPLLLDKSKKHDENPAYQDSLMIDGIGDAYSRKPMGITAENV 163
Query: 433 AKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPV 546
A K ITRQD DE+A +S+ ++ AA E F +E P+
Sbjct: 164 ADKYHITRQDMDEFARDSHAKAYAAQENDWFKEEYAPI 201
>UniRef50_Q1VJ45 Cluster: Acetyl-CoA acetyltransferase; n=1;
Psychroflexus torquis ATCC 700755|Rep: Acetyl-CoA
acetyltransferase - Psychroflexus torquis ATCC 700755
Length = 371
Score = 118 bits (284), Expect = 1e-25
Identities = 59/152 (38%), Positives = 93/152 (61%), Gaps = 2/152 (1%)
Frame = +1
Query: 88 IKXVYIGNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQ 267
++ + +G V ++ LG A Q + +G+ +S+ VN+VC SGM++ + A+ + T
Sbjct: 38 VEGLVLGQVLTSGLGMNTARQVALKSGMSQSSFAYVVNQVCGSGMRAAIEASLKIFTQES 97
Query: 268 DIILAGGMESMSNVPF-YLKR-GETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKK 441
D+++AGG ESMS YL R GE G +D ++ DGLTD +++ HMG AEN A+K
Sbjct: 98 DLVIAGGQESMSRARHAYLSRTGEKKLGNNIFIDTLIHDGLTDAFSQEHMGITAENVARK 157
Query: 442 LQITRQDQDEYAVNSYKRSAAAYEAKAFVDEL 537
+TRQ+QD+YA SY ++ A + K F +EL
Sbjct: 158 YNVTRQEQDQYAYGSYSKAYKALKNKYFKNEL 189
>UniRef50_Q236D4 Cluster: Acetyl-CoA acyltransferases family protein;
n=1; Tetrahymena thermophila SB210|Rep: Acetyl-CoA
acyltransferases family protein - Tetrahymena thermophila
SB210
Length = 1352
Score = 118 bits (284), Expect = 1e-25
Identities = 60/191 (31%), Positives = 98/191 (51%), Gaps = 2/191 (1%)
Frame = +1
Query: 1 GRFSXFXXXXXXXXXXXXXIEXAGIPKXXIKXVYIGNVCSANLGQAPAXQAVIFAGLPKS 180
G+ + F I + I V++G A +GQ PA QA + G+
Sbjct: 978 GKLAKFRAPDLAGFSIQSAIRDIKLQPDQIDEVFLGVALPAMIGQNPAKQAALLGGVDIE 1037
Query: 181 TICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPFYL--KRGETSYGGMQ 354
C+TVNK C+SG+KS+++ A + G ++ GG ESMSNVPFY+ +R +G +
Sbjct: 1038 VPCSTVNKACSSGLKSVIVGANSINVGYNQCVVTGGFESMSNVPFYMYQQRRGKQFGDSK 1097
Query: 355 LVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDE 534
L+DGI+ DG+ D Y++ +G AE K ++ +Q D A+ SY+R+ A + +
Sbjct: 1098 LLDGILNDGVQDKYSEQPLGYLAEQLCKNMKFQKQTVDAVAIASYERAIEARDNGFLAKQ 1157
Query: 535 LVPVPVPQKRG 567
+ P+ +G
Sbjct: 1158 ISPIQYHDGQG 1168
>UniRef50_Q835L3 Cluster: Acetyl-CoA
acetyltransferase/hydroxymethylglutaryl-CoA reductase,
degradative; n=86; cellular organisms|Rep: Acetyl-CoA
acetyltransferase/hydroxymethylglutaryl-CoA reductase,
degradative - Enterococcus faecalis (Streptococcus
faecalis)
Length = 803
Score = 117 bits (281), Expect = 2e-25
Identities = 60/155 (38%), Positives = 91/155 (58%)
Frame = +1
Query: 88 IKXVYIGNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQ 267
I V GNV A GQ PA Q I +GL TVN+VC SGMK+++LA Q +Q G
Sbjct: 48 IDQVIFGNVLQAGNGQNPARQIAINSGLSHEIPAMTVNEVCGSGMKAVILAKQLIQLGEA 107
Query: 268 DIILAGGMESMSNVPFYLKRGETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQ 447
++++AGG+E+MS P + + +++DGLTD ++ MG AEN A+K
Sbjct: 108 EVLIAGGIENMSQAPKLQRFNYETESYDAPFSSMMYDGLTDAFSGQAMGLTAENVAEKYH 167
Query: 448 ITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPV 552
+TR++QD+++V+S ++A A F DE+ P+ V
Sbjct: 168 VTREEQDQFSVHSQLKAAQAQAEGIFADEIAPLEV 202
>UniRef50_A1I8P5 Cluster: Acetyl-CoA C-acetyltransferase; n=6;
Bacteria|Rep: Acetyl-CoA C-acetyltransferase -
Candidatus Desulfococcus oleovorans Hxd3
Length = 405
Score = 115 bits (277), Expect = 7e-25
Identities = 65/173 (37%), Positives = 96/173 (55%), Gaps = 3/173 (1%)
Frame = +1
Query: 58 IEXAGIPKXXIKXVYIGNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIML 237
+E A I K ++ V G A A + AGLP ++ TV++ CAS M+ L
Sbjct: 49 LEKAKIDKSLVQEVVCGQCNQAGAPGNTARHIAMGAGLPATSFAFTVHQQCASSMRGTEL 108
Query: 238 AAQGLQTGAQDIILAGGMESMSNVPFYL---KRGETSYGGMQLVDGIVFDGLTDVYNKFH 408
AQ + G DI G+ESMSN P+ L +RG G + D ++ GL D +H
Sbjct: 109 VAQEIMLGKIDIGAVVGVESMSNAPYLLFGARRGYRLSDGETVQDSLMIGGLVDALLGYH 168
Query: 409 MGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPVPQKRG 567
MG AEN A+K +I+RQ+QDE+A+ S++R+ AA + F +E+VPV + K+G
Sbjct: 169 MGVTAENIAEKYKISRQEQDEWALMSHQRAVAAIQKGWFAEEIVPVTIKTKKG 221
>UniRef50_A1SPA4 Cluster: Acetyl-CoA acetyltransferases; n=6;
Bacteria|Rep: Acetyl-CoA acetyltransferases -
Nocardioides sp. (strain BAA-499 / JS614)
Length = 397
Score = 115 bits (276), Expect = 1e-24
Identities = 65/171 (38%), Positives = 94/171 (54%), Gaps = 2/171 (1%)
Frame = +1
Query: 58 IEXAGIPKXXIKXVYIGNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIML 237
+ AG+ I V +G + A + + AGLP T TVN++C SG++++
Sbjct: 45 LRRAGVEAEAIDEVIMGCIGQVGPDAYNARRVALAAGLPDRTPAYTVNRLCGSGLQAVWS 104
Query: 238 AAQGLQTGAQDIILAGGMESMSNVPFYLKRGETSY--GGMQLVDGIVFDGLTDVYNKFHM 411
AA ++ GA ++ LAGG ESM+ +PFY Y G LVDG V LTD ++ HM
Sbjct: 105 AAMQIRWGAAELALAGGDESMTRMPFYDFGARAGYKLGDRALVDGTVM-MLTDPFHGIHM 163
Query: 412 GNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPVPQKR 564
G AE A+K +TR +QDE+A S +R+A AF +E+VPV V +R
Sbjct: 164 GVTAERVAEKYGVTRAEQDEFAAESQRRAATPEARAAFAEEIVPVEVGGRR 214
>UniRef50_O51136 Cluster: Acetyl-CoA C-acetyltransferase; n=3;
Borrelia burgdorferi group|Rep: Acetyl-CoA
C-acetyltransferase - Borrelia burgdorferi (Lyme disease
spirochete)
Length = 398
Score = 114 bits (275), Expect = 1e-24
Identities = 65/163 (39%), Positives = 92/163 (56%), Gaps = 4/163 (2%)
Frame = +1
Query: 88 IKXVYIGNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQ 267
+ V IGNV SA LGQ A Q + + L + +VNKVC SG+K++ LA + G
Sbjct: 47 VDEVIIGNVISAGLGQNIARQIALKSDLGDTVPAFSVNKVCGSGLKALELAFNSIALGDN 106
Query: 268 DIILAGGMESMSNVPFYLKR----GETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTA 435
DI+LAGG+E ++N P+ L R +G + D I D L D N MG AEN +
Sbjct: 107 DIVLAGGVEDLTNSPYLLPRKIRFDGLKFGNFGIEDSIQKDALIDSLNFISMGLTAENLS 166
Query: 436 KKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPVPQKR 564
+K +ITR+ QDE+A NS+ ++ A E F DE+ P+ V K+
Sbjct: 167 EKYRITREMQDEFAYNSHVKALKARELGYFEDEIYPLTVFDKK 209
>UniRef50_Q0AYU4 Cluster: Acetyl-CoA C-acetyltransferase; n=4;
Clostridiales|Rep: Acetyl-CoA C-acetyltransferase -
Syntrophomonas wolfei subsp. wolfei (strain Goettingen)
Length = 403
Score = 114 bits (274), Expect = 2e-24
Identities = 64/175 (36%), Positives = 96/175 (54%), Gaps = 2/175 (1%)
Frame = +1
Query: 58 IEXAGIPKXXIKXVYIGNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIML 237
I+ AGI I + +G V G PA Q I AGLP + VN+ CASGM+++ +
Sbjct: 42 IKRAGIQPDIIDEIVMGEVYPHMQGSLPARQVGIAAGLPVRSNACNVNQNCASGMRALDV 101
Query: 238 AAQGLQTGAQDIILAGGMESMSNVPFYLKRGETSY--GGMQLVDGIVFDGLTDVYNKFHM 411
A +Q G D+ L G+ESM+N P+ + + Y G + D ++ DGL D HM
Sbjct: 102 ALTHIQLGKTDVALVVGVESMTNAPYMIPKARMGYRMGPGSIEDAMLHDGLIDRLVPGHM 161
Query: 412 GNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPVPQKRGAPV 576
G AEN A+K ITR++ D+ A+ S++R+ A + F E+VPV + K+G +
Sbjct: 162 GVTAENIAEKYGITREECDQLALASHQRATRATQDGTFQREIVPVELKSKKGVKI 216
>UniRef50_Q8SXL6 Cluster: RE07481p; n=1; Drosophila
melanogaster|Rep: RE07481p - Drosophila melanogaster
(Fruit fly)
Length = 241
Score = 112 bits (269), Expect = 7e-24
Identities = 61/156 (39%), Positives = 86/156 (55%), Gaps = 2/156 (1%)
Frame = +1
Query: 58 IEXAGIPKXXIKXVYIGNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIML 237
+ A + + V +G SA GQ PA QA + AGLP +N +C SG+K++ L
Sbjct: 38 LRRANVEGQEVNEVILGQALSAGQGQNPARQASLKAGLPIQVPAYGINMLCGSGLKTVAL 97
Query: 238 AAQGLQTGAQDIILAGGMESMSNVP--FYLKRGETSYGGMQLVDGIVFDGLTDVYNKFHM 411
Q +++G I++AGG ESMS P +L++G G +VD ++ DGLTD HM
Sbjct: 98 GYQAIRSGDAQIVVAGGQESMSLAPHVMHLRQG-VKMGPGTMVDSMIHDGLTDAMENIHM 156
Query: 412 GNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAK 519
G AEN A K I+R+ QD YAV S R+ A + K
Sbjct: 157 GITAENLADKYNISREAQDAYAVLSQNRAEEAQKKK 192
>UniRef50_Q43974 Cluster: Beta-ketoadipyl-CoA thiolase; n=274;
Bacteria|Rep: Beta-ketoadipyl-CoA thiolase -
Acinetobacter sp. (strain ADP1)
Length = 401
Score = 109 bits (262), Expect = 5e-23
Identities = 55/154 (35%), Positives = 89/154 (57%), Gaps = 6/154 (3%)
Frame = +1
Query: 151 AVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPFYLKRG 330
+ + AGLP TTVN++C S + +I +AA+ ++ G +I+AGG+ESMS P+ + +
Sbjct: 71 SALLAGLPVEVPATTVNRLCGSSLDAIAMAARAIKAGEAHLIIAGGVESMSRAPYVMGKS 130
Query: 331 ETSYGGMQLVDG------IVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYK 492
E ++G Q ++ + L +Y M AEN A++ I R+DQD++A S +
Sbjct: 131 EGAFGRTQKIEDTTMGWRFINPKLKAMYGVDTMPQTAENVAEQFGIQREDQDQFAYTSQQ 190
Query: 493 RSAAAYEAKAFVDELVPVPVPQKRGAPVIFAEXE 594
R+AAA F E+VPV +PQ++G PV+ E
Sbjct: 191 RTAAAQAKGYFAKEIVPVTIPQRKGEPVVIDTDE 224
>UniRef50_Q22106 Cluster: Putative uncharacterized protein; n=1;
Caenorhabditis elegans|Rep: Putative uncharacterized
protein - Caenorhabditis elegans
Length = 460
Score = 107 bits (256), Expect = 3e-22
Identities = 56/102 (54%), Positives = 71/102 (69%)
Frame = +1
Query: 97 VYIGNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDII 276
V++G VC AN GQA A QA + AGL S TTVNK +SGMK+I+LAAQ +QTG QD+
Sbjct: 151 VFLGQVCHANAGQASARQAALGAGLDLSVAVTTVNKGWSSGMKAIILAAQQIQTGHQDLA 210
Query: 277 LAGGMESMSNVPFYLKRGETSYGGMQLVDGIVFDGLTDVYNK 402
+ GGMESMS VPF+L R E S Q V+ V DG++D ++K
Sbjct: 211 IGGGMESMSQVPFFLARVEQSSNKYQ-VEQTVQDGISDFFDK 251
>UniRef50_Q5C0R7 Cluster: SJCHGC03323 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC03323 protein - Schistosoma
japonicum (Blood fluke)
Length = 237
Score = 105 bits (253), Expect = 6e-22
Identities = 66/172 (38%), Positives = 94/172 (54%), Gaps = 16/172 (9%)
Frame = +1
Query: 88 IKXVYIGNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQ 267
++ V IG V +A+ GQ PA QA I AG+P VN +C SG+KS+ L L +
Sbjct: 62 LEEVIIGQVLTASAGQNPARQAAILAGIPYCVPAWCVNMMCGSGLKSVCLGFDRLSLSSM 121
Query: 268 DI---ILAGGMESMSNVPFY------LKR--GETS-----YGGMQLVDGIVFDGLTDVYN 399
ILAGG ESMS P L+R G+ + YG L+D I+ D L D +
Sbjct: 122 TDGGWILAGGQESMSQAPHATPPRACLRRVGGQNTSELPNYGNFTLLDTIMNDALMDAFC 181
Query: 400 KFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPVP 555
MG AEN AK+ I+R++QD +A+ S ++ A A +A F++E+ P+ VP
Sbjct: 182 NLPMGGTAENVAKRFGISREEQDVFALRSQEKYAFALKAGYFINEITPIKVP 233
>UniRef50_Q9RRK9 Cluster: Acetyl-CoA acetyltransferase; n=12;
Bacteria|Rep: Acetyl-CoA acetyltransferase - Deinococcus
radiodurans
Length = 399
Score = 105 bits (252), Expect = 8e-22
Identities = 66/166 (39%), Positives = 95/166 (57%), Gaps = 1/166 (0%)
Frame = +1
Query: 58 IEXAGIPKXXIKXVYIG-NVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIM 234
I+ AG+ ++ VY+G + A G A A + AGLP S TVN+ C+SG+++I
Sbjct: 39 IKRAGVDAGVVEDVYLGCAIPEAEQGLNVARLAALRAGLPDSVGGVTVNRFCSSGLQTIA 98
Query: 235 LAAQGLQTGAQDIILAGGMESMSNVPFYLKRGETSYGGMQLVDGIVFDGLTDVYNKFHMG 414
+AA +QTG D++LAGG+ESMS +P G LV D Y MG
Sbjct: 99 MAAAAIQTGQADVMLAGGVESMSMLPM---SGHNPSPNPDLV-----DDRPGAY--IGMG 148
Query: 415 NCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPV 552
AEN A K ++R+DQD++A S++++AAA +A F E+VPVPV
Sbjct: 149 MTAENVAAKYGVSREDQDKFAYASHQKAAAAQDAGKFDAEIVPVPV 194
>UniRef50_A4TXT3 Cluster: Acetyl-CoA acetyltransferase; n=1;
Magnetospirillum gryphiswaldense|Rep: Acetyl-CoA
acetyltransferase - Magnetospirillum gryphiswaldense
Length = 240
Score = 105 bits (251), Expect = 1e-21
Identities = 60/172 (34%), Positives = 84/172 (48%), Gaps = 3/172 (1%)
Frame = +1
Query: 1 GRFSXFXXXXXXXXXXXXXIEXAGIPKXXIKXVYIGNVCSANLGQAPAXQAVIFAGLPKS 180
G S + A + ++ V +G V A GQAPA QA AG+P +
Sbjct: 21 GELSGLTASQLGAHAIKAALTRANVAADQVEEVIMGCVLPAGQGQAPARQASRGAGIPDA 80
Query: 181 TICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPFYLKRGETSY--GGMQ 354
TT+NK+C SGMK+ M A L G +++AGGMESM+N P+ L + Y G +
Sbjct: 81 AGATTINKMCGSGMKAAMFAHDMLIAGTNRVMVAGGMESMTNAPYLLDKARGGYRMGHGR 140
Query: 355 LVDGIVFDGLTDVYNKFH-MGNCAENTAKKLQITRQDQDEYAVNSYKRSAAA 507
++D + DGL D Y+K MG E Q TRQ Q ++ + S R A
Sbjct: 141 VMDHMFLDGLEDAYDKGRLMGTFPEGCGPSFQFTRQGQAQFGLRSAGRRCKA 192
>UniRef50_Q8ESF0 Cluster: Thiolase B; n=5; Bacteria|Rep: Thiolase B
- Oceanobacillus iheyensis
Length = 394
Score = 104 bits (250), Expect = 1e-21
Identities = 64/184 (34%), Positives = 98/184 (53%), Gaps = 5/184 (2%)
Frame = +1
Query: 58 IEXAGIPKXXIKXVYIGNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIML 237
+ +P I V +G V + A A + AG+P+ TVN++CASG++++
Sbjct: 39 LRRVNLPADHIDEVILGEVRQSTESSNIARVAALRAGIPEQVTAFTVNRLCASGIQAVTS 98
Query: 238 AAQGLQTGAQDIILAGGMESMSNVPFYLKRGETSYGG--MQLVDGIVFDGL--TDVYNK- 402
Q + + DI++AGG ESMS P YL+ T +GG +VD + G ++Y K
Sbjct: 99 GVQQILSNQADIVVAGGAESMSRSPIYLR--NTRFGGDRTTIVDSNLEAGQQPPEIYGKS 156
Query: 403 FHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPVPQKRGAPVIF 582
MG AEN A+K +I+R+DQD +A+ S R+ A E F E+ P+ V +K+ V F
Sbjct: 157 LSMGITAENVARKYKISREDQDAFALESQHRAKKAIETGRFKKEIAPIEVKEKKQTSV-F 215
Query: 583 AEXE 594
A E
Sbjct: 216 AVDE 219
>UniRef50_Q4TEZ1 Cluster: Chromosome undetermined SCAF4980, whole
genome shotgun sequence; n=1; Tetraodon
nigroviridis|Rep: Chromosome undetermined SCAF4980,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 159
Score = 103 bits (247), Expect = 3e-21
Identities = 60/127 (47%), Positives = 76/127 (59%), Gaps = 25/127 (19%)
Frame = +1
Query: 289 MESMSNVPFYLKRGETSYGGMQLVDGIVFDGLTDVYNKFHM------------------- 411
MESMSNVP+ + R YGG+++ D IV DGLTDVYNKFHM
Sbjct: 1 MESMSNVPYVMSRESPVYGGVKMEDLIVKDGLTDVYNKFHMVTTSRLSCCRSPTFPLRSA 60
Query: 412 ------GNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPVPQKRGAP 573
GNCAENTAK+ +I+R++QD YAV SY RS AA++A E+V V VPQ+ A
Sbjct: 61 VAPRHQGNCAENTAKQSRISREEQDAYAVGSYSRSQAAHQAGVLAKEIVAVSVPQRGKAD 120
Query: 574 VIFAEXE 594
V+ +E E
Sbjct: 121 VLVSEDE 127
>UniRef50_Q0K0C1 Cluster: Acetyl-CoA acetyltransferase; n=11;
Proteobacteria|Rep: Acetyl-CoA acetyltransferase -
Ralstonia eutropha (strain ATCC 17699 / H16 / DSM 428 /
Stanier 337)(Cupriavidus necator (strain ATCC 17699 /
H16 / DSM 428 / Stanier337))
Length = 395
Score = 103 bits (247), Expect = 3e-21
Identities = 61/172 (35%), Positives = 84/172 (48%), Gaps = 2/172 (1%)
Frame = +1
Query: 58 IEXAGIPKXXIKXVYIGNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIML 237
+ AGI + V GNV A PA QA I AGLP S TVN+VC SG ++I
Sbjct: 40 VARAGIDPGEVGSVVFGNVIQAGNRMNPARQAAIGAGLPVSVPAMTVNRVCGSGAQAIAT 99
Query: 238 AAQGLQTGAQDIILAGGMESMSNVPFYLKRGE--TSYGGMQLVDGIVFDGLTDVYNKFHM 411
AA ++ G DI +AGGME+M P+ + G G L D ++ DGL D ++ H
Sbjct: 100 AADEVRLGYVDIAIAGGMENMDRAPYLMPSGRWGQRMGDSVLYDSMLHDGLFDAFSGEHS 159
Query: 412 GNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPVPQKRG 567
G E+ + +TR+ QD +A S + A A F ++ V K G
Sbjct: 160 GWHTEDLVARYALTREAQDRWAERSQRNFALAQANGRFTGQIAGVATKGKGG 211
>UniRef50_Q8ESG3 Cluster: Acetyl-CoA acetyltransferase; n=4;
Firmicutes|Rep: Acetyl-CoA acetyltransferase -
Oceanobacillus iheyensis
Length = 391
Score = 101 bits (241), Expect = 2e-20
Identities = 64/182 (35%), Positives = 101/182 (55%), Gaps = 3/182 (1%)
Frame = +1
Query: 58 IEXAGIPKXXIKXVYIGNVCSA--NLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSI 231
++ A + I V +GNV S N+ + A QA + LP TI ++ C SG+ +I
Sbjct: 41 VKRAKVDPELIDDVIMGNVLSGGGNIARLAALQADLSLHLPGLTI----DRQCGSGINAI 96
Query: 232 MLAAQGLQTGAQDIILAGGMESMSNVPFYLKRGETSYGGMQLVDGIVFDGLTDVY-NKFH 408
+LA Q +Q+G DI +AGGMESMS P+ + R + ++ + I L+ +
Sbjct: 97 VLAQQAIQSGMGDIYVAGGMESMSRAPYLMDRPDKAFSPVPPT--IRKSKLSPEHIGDPP 154
Query: 409 MGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPVPQKRGAPVIFAE 588
MG AEN AKK I+R++QDEYA++S +R A F +++VP+ VP ++ A ++F
Sbjct: 155 MGITAENLAKKYNISREEQDEYALSSQQRMEEAMREGRFKEQIVPISVPLRKEAAIVFDT 214
Query: 589 XE 594
E
Sbjct: 215 DE 216
>UniRef50_A5UXI0 Cluster: Acetyl-CoA acetyltransferase; n=5;
cellular organisms|Rep: Acetyl-CoA acetyltransferase -
Roseiflexus sp. RS-1
Length = 391
Score = 98.3 bits (234), Expect = 1e-19
Identities = 62/163 (38%), Positives = 91/163 (55%), Gaps = 2/163 (1%)
Frame = +1
Query: 70 GIPKXXIKXVYIGNVC-SANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQ 246
G+ I V +G A G A A++ AGLP TVN+ CASG+++I LAAQ
Sbjct: 44 GLDPKEIDDVILGCAMPEAEQGLNMARVALLRAGLPTDVPGQTVNRFCASGLQTIALAAQ 103
Query: 247 GLQTGAQDIILAGGMESMSNVPFYLKRGETSYGGMQLVDGIVFDGLT-DVYNKFHMGNCA 423
+ +G D+++AGG ESMS VP GG ++ DVY MG A
Sbjct: 104 QVMSGMGDVVVAGGAESMSAVPM---------GGHHFAPNPAMAEMSPDVY--LGMGLTA 152
Query: 424 ENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPV 552
EN A++ +++R+DQD +A+ S++R+ AA +A F DE+VP+ V
Sbjct: 153 ENVARRYEVSREDQDAFALRSHQRAIAAIDAGLFKDEIVPIEV 195
>UniRef50_Q62JZ3 Cluster: Beta-ketothiolase; n=107; Bacteria|Rep:
Beta-ketothiolase - Burkholderia mallei (Pseudomonas
mallei)
Length = 394
Score = 97.9 bits (233), Expect = 2e-19
Identities = 54/151 (35%), Positives = 86/151 (56%), Gaps = 2/151 (1%)
Frame = +1
Query: 142 AXQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPFYL 321
A A I G+ + TVN++C SG+++I+ AAQ + G DI +AGG E+MS P+ +
Sbjct: 68 ARVAAINGGVAQHAPALTVNRLCGSGLQAIVSAAQNVLLGDADIAVAGGAENMSRAPYSV 127
Query: 322 K--RGETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKR 495
R G +LVD ++ L D + HMG AEN A K ITR QD A+ S++R
Sbjct: 128 PAARFGQRMGDAKLVD-MMIGALNDPFQSIHMGVTAENVAAKYGITRDAQDALALESHRR 186
Query: 496 SAAAYEAKAFVDELVPVPVPQKRGAPVIFAE 588
++ A ++ F D+++P+ + ++G V A+
Sbjct: 187 ASHATKSGYFKDQILPIEIASRKGTVVFDAD 217
>UniRef50_P73825 Cluster: Acetyl coenzyme A acetyltransferase; n=1;
Synechocystis sp. PCC 6803|Rep: Acetyl coenzyme A
acetyltransferase - Synechocystis sp. (strain PCC 6803)
Length = 409
Score = 96.3 bits (229), Expect = 5e-19
Identities = 64/202 (31%), Positives = 96/202 (47%), Gaps = 6/202 (2%)
Frame = +1
Query: 1 GRFSXFXXXXXXXXXXXXXIEXAGIPKXXIKXVYIGNVCSANLGQAPAXQAVIFAGLPKS 180
G + F + AG+ + +GNV A GQ QA + A +P +
Sbjct: 32 GSLTNFSAADLGAHVMKSVLAQAGVGGDQLDLYIMGNVLRAGHGQLIPRQAALKAEIPDT 91
Query: 181 TICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPFYLK-RGETSYGGM-- 351
V+ VC+S M S++ AA ++ G D+ILAGG ESMS FYL R Y +
Sbjct: 92 VDGYAVDMVCSSAMMSVINAALTIRAGEGDLILAGGTESMSQTGFYLSHRARWGYKFLMG 151
Query: 352 ---QLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKA 522
L D ++ DGLTD N MG E A + +R + DE A S +R+A A E+
Sbjct: 152 APENLTDLLLHDGLTDSTNGEGMGEQTEKLAAEHGFSRIELDEVACLSQQRAAHATESGY 211
Query: 523 FVDELVPVPVPQKRGAPVIFAE 588
F E+ P+ + ++G V+ ++
Sbjct: 212 FDSEIAPIEITSRKGTQVLASD 233
>UniRef50_P42765 Cluster: 3-ketoacyl-CoA thiolase, mitochondrial;
n=62; cellular organisms|Rep: 3-ketoacyl-CoA thiolase,
mitochondrial - Homo sapiens (Human)
Length = 397
Score = 95.1 bits (226), Expect = 1e-18
Identities = 56/192 (29%), Positives = 94/192 (48%), Gaps = 3/192 (1%)
Frame = +1
Query: 1 GRFSXFXXXXXXXXXXXXXIEXAGIPKXXIKXVYIGNVCSANLGQAPAXQAV-IFAGLPK 177
G F + + + V +GNV ++ + V + G+PK
Sbjct: 22 GLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVLQSSSDAIYLARHVGLRVGIPK 81
Query: 178 STICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPFYLK--RGETSYGGM 351
T T+N++C SG +SI+ Q + +++L GG ESMS P+ ++ R T G
Sbjct: 82 ETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTESMSQAPYCVRNVRFGTKLGSD 141
Query: 352 QLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVD 531
++ ++ LTD + + M AEN A K +I+R++ D+YA+ S +R AA +A F D
Sbjct: 142 IKLEDSLWVSLTDQHVQLPMAMTAENLAVKHKISREECDKYALQSQQRWKAANDAGYFND 201
Query: 532 ELVPVPVPQKRG 567
E+ P+ V K+G
Sbjct: 202 EMAPIEVKTKKG 213
>UniRef50_A6CQ12 Cluster: Acetyl-CoA acetyltransferase; n=1;
Bacillus sp. SG-1|Rep: Acetyl-CoA acetyltransferase -
Bacillus sp. SG-1
Length = 391
Score = 94.7 bits (225), Expect = 1e-18
Identities = 58/167 (34%), Positives = 89/167 (53%), Gaps = 3/167 (1%)
Frame = +1
Query: 88 IKXVYIGNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQ 267
I V +G+ A A + AG +T T+ + CASGM++I+ A +QTG
Sbjct: 48 IDEVILGHCIQRTDQPNTARTAALLAGFSDTTTGYTIQRQCASGMQAIISAYMQIQTGMS 107
Query: 268 DIILAGGMESMSNVPFYLKR---GETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAK 438
DI+LAGG+E+MS+ P+ +K G+ G + V++ L D + MG AEN A+
Sbjct: 108 DIVLAGGVEAMSSSPYVMKGHRWGQRLQHGE--IRDTVWEALEDPIHGIMMGETAENLAE 165
Query: 439 KLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPVPQKRGAPVI 579
ITR+DQDE A S++R+ A E F ++VP+ V ++ I
Sbjct: 166 IHNITREDQDELAKLSHERAVKAAEEGYFDSQIVPIEVKSRKETKTI 212
>UniRef50_Q97W61 Cluster: Acetyl-CoA c-acetyltransferase; n=22;
cellular organisms|Rep: Acetyl-CoA c-acetyltransferase -
Sulfolobus solfataricus
Length = 397
Score = 93.9 bits (223), Expect = 3e-18
Identities = 60/175 (34%), Positives = 93/175 (53%), Gaps = 7/175 (4%)
Frame = +1
Query: 58 IEXAGIPKXXIKXVYIGNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIML 237
+ A + I +GNV A GQ A Q I AG+P +V+ VC+SGM S++
Sbjct: 39 LRRANVEPGKIDMAIMGNVLRAGHGQDIARQCAISAGIPFEIDGFSVDMVCSSGMISVIT 98
Query: 238 AAQGLQTGAQDIILAGGMESMSNVPFYLKRGETSYG-------GMQLVDGIVFDGLTDVY 396
A+Q +++G DII+AGG E+MS F +K + +G ++L+D +++DGLTD +
Sbjct: 99 ASQMIKSGDADIIVAGGTENMSQAMFAIK-SDIRWGVKMLMNRNIELIDTMLYDGLTDPF 157
Query: 397 NKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPVPQK 561
MG A+ AK I+R++ DE A S+ R+ A F E+V + K
Sbjct: 158 QYKVMGQEADMVAKSHNISRKELDEVAYQSHLRAHKATVNGYFKSEIVEIKADGK 212
>UniRef50_Q89DN9 Cluster: Acetyl-CoA acetyltransferase; n=1;
Bradyrhizobium japonicum|Rep: Acetyl-CoA
acetyltransferase - Bradyrhizobium japonicum
Length = 390
Score = 93.5 bits (222), Expect = 3e-18
Identities = 57/170 (33%), Positives = 101/170 (59%), Gaps = 2/170 (1%)
Frame = +1
Query: 58 IEXAGIPKXXIKXVYIGNVC--SANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSI 231
++ AG+ K ++ Y+GN + N+G+ QA + AGLPK+T +VN+ C+SG+++I
Sbjct: 39 VDRAGVDKDYVEDCYLGNCAHGAPNIGR----QAALLAGLPKTTAGVSVNRFCSSGLQTI 94
Query: 232 MLAAQGLQTGAQDIILAGGMESMSNVPFYLKRGETSYGGMQLVDGIVFDGLTDVYNKFHM 411
+AA +++ D I+AGG+ES+S VP G T + +D + D++ M
Sbjct: 95 AMAANSIRSDGADCIVAGGVESIS-VP----GGGTP---KESIDPELLKVAPDIF--MAM 144
Query: 412 GNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPVPQK 561
+ A+ A++ +++R+ QDE+++ S +R AAA +A F DE+VP+ K
Sbjct: 145 IDTADIVAERYKLSREYQDEFSLESQRRMAAAQQANKFKDEIVPMKTKMK 194
>UniRef50_Q82UG2 Cluster: Thiolase; n=98; Bacteria|Rep: Thiolase -
Nitrosomonas europaea
Length = 400
Score = 93.5 bits (222), Expect = 3e-18
Identities = 57/167 (34%), Positives = 90/167 (53%), Gaps = 2/167 (1%)
Frame = +1
Query: 70 GIPKXXIKXVYIGNVC-SANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQ 246
G+ I+ V +G A G A A++ AGLP S T+N+ CASG++++ +AA
Sbjct: 48 GLDPAAIEDVIVGCAMPEAEQGINVARVALLLAGLPVSVPGVTINRFCASGLQAVAMAAD 107
Query: 247 GLQTGAQDIILAGGMESMSNVPFYLKRGETSYGGMQLVDGIVF-DGLTDVYNKFHMGNCA 423
++ G D+I+AGG ESMS VP G ++ +F G V + MG A
Sbjct: 108 RIRLGEADVIIAGGTESMSMVPM--------MGNKVAMNPALFKPGSEQVAIAYGMGITA 159
Query: 424 ENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPVPQKR 564
E A++ +++R++QD +A+ S+ R+ A E F DE+ P PV + R
Sbjct: 160 EKVAEQWKVSREEQDAFALESHHRAIRAIEQGEFRDEISPYPVQENR 206
>UniRef50_Q0SDR4 Cluster: Acetyl-CoA C-acetyltransferase; n=31;
Bacteria|Rep: Acetyl-CoA C-acetyltransferase -
Rhodococcus sp. (strain RHA1)
Length = 411
Score = 92.7 bits (220), Expect = 6e-18
Identities = 57/168 (33%), Positives = 95/168 (56%), Gaps = 8/168 (4%)
Frame = +1
Query: 115 CSANLGQAPAXQAVIF--AGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGG 288
C N G+APA V+ AG+P + +++ C SG+++++ AA +QTG ++++AGG
Sbjct: 64 CYPN-GEAPAIGRVVALDAGMPVTVPGQQLDRRCGSGLQAVLDAAMRVQTGIAELVIAGG 122
Query: 289 MESMSNVPFYLK------RGETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQI 450
+ESMS +Y + +G + +L G V G + M AEN +K I
Sbjct: 123 VESMSRAEYYTESMRWGAKGAPAVLHDRLARGRVTAGGRNYPVPGGMLETAENLRRKYDI 182
Query: 451 TRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPVPQKRGAPVIFAEXE 594
+R +QDE AV+S++R+ AA ++ F +E+VPV VP ++G P + E
Sbjct: 183 SRLEQDELAVSSHQRAVAAIDSGKFAEEIVPVEVPVRKGDPQVVDRDE 230
>UniRef50_A6T953 Cluster: Putative acetyl-CoA acetyltransferase;
n=1; Klebsiella pneumoniae subsp. pneumoniae MGH
78578|Rep: Putative acetyl-CoA acetyltransferase -
Klebsiella pneumoniae subsp. pneumoniae MGH 78578
Length = 396
Score = 92.7 bits (220), Expect = 6e-18
Identities = 54/181 (29%), Positives = 96/181 (53%), Gaps = 2/181 (1%)
Frame = +1
Query: 58 IEXAGIPKXXIKXVYIGNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIML 237
I AGI I +GNV A + AG+P+ + +VN+ C SG++++
Sbjct: 41 IARAGIAPQDIDETIVGNVGQIAESGFIARICQLRAGIPQESTAYSVNRQCGSGLQALAD 100
Query: 238 AAQGLQTGAQDIILAGGMESMSNVPFYLKRGETSY--GGMQLVDGIVFDGLTDVYNKFHM 411
LQ+G ++++A G E+M+ +P+YL++ Y G +L DG++ LT +H
Sbjct: 101 GMMQLQSGQAEVVVACGTENMTQLPYYLRKARDGYRMGHGELEDGLI-SILTWPEGPYHN 159
Query: 412 GNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPVPQKRGAPVIFAEX 591
G AEN A++ ITR+ D++A +S +++ A F ++++ + VP + A +FA
Sbjct: 160 GITAENVAQRFGITREAMDDFAWSSQQKALKAIAEGRFREQILALEVPDGKKATRLFATD 219
Query: 592 E 594
E
Sbjct: 220 E 220
>UniRef50_Q0RXS1 Cluster: Acetyl-CoA C-acetyltransferase; n=1;
Rhodococcus sp. RHA1|Rep: Acetyl-CoA C-acetyltransferase
- Rhodococcus sp. (strain RHA1)
Length = 388
Score = 91.9 bits (218), Expect = 1e-17
Identities = 55/151 (36%), Positives = 80/151 (52%), Gaps = 1/151 (0%)
Frame = +1
Query: 88 IKXVYIGNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQ 267
I ++GNV A GQ PA A I G+P + TT+N VC + + + +AA ++ G
Sbjct: 50 IDHTFLGNVVQAGNGQNPARVAAIHGGVPTTVPGTTINDVCLASVTATGMAASMIRGGEI 109
Query: 268 DIILAGGMESMSNVPFYLK-RGETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKL 444
D L GG ESMS ++ R G LVD +V DGL + MG ++ ++
Sbjct: 110 DTALVGGFESMSRALHGVQVRAAAKVGHGGLVDLLVNDGLWCAVSDSGMGEISDQANREH 169
Query: 445 QITRQDQDEYAVNSYKRSAAAYEAKAFVDEL 537
ITR DQDE+A S++R+ AA E+ F E+
Sbjct: 170 GITRADQDEFACASHRRATAATESGRFKQEI 200
>UniRef50_Q9RZA1 Cluster: Acetyl-CoA acetyltransferase; n=4;
root|Rep: Acetyl-CoA acetyltransferase - Deinococcus
radiodurans
Length = 461
Score = 91.5 bits (217), Expect = 1e-17
Identities = 57/191 (29%), Positives = 99/191 (51%), Gaps = 18/191 (9%)
Frame = +1
Query: 58 IEXAGIPKXXIKXVYIGNVCSANLGQAP---AXQAVIFAGLPKSTICTTVNKVCASGMKS 228
+ +G+P I+ V G C+ G+ A A + AGLP++ TVN++CASG+ +
Sbjct: 82 VARSGVPATEIEEVIFG--CANQAGEDNRNVARMAALLAGLPETVAGVTVNRLCASGLAA 139
Query: 229 IMLAAQGLQTGAQDIILAGGMESMSNVPFYLKRGETSY--GGMQLVDGIV-----FDGLT 387
+ +AA+ ++ G D+ + GG+ESM+ P + +G ++ G + D + +
Sbjct: 140 VNMAARAIRNGDGDVYVVGGVESMTRAPLSMPKGSAAFANGNVTAYDTTLGWRYPNPAME 199
Query: 388 DVYNKFHMGNCAENTAKKL--------QITRQDQDEYAVNSYKRSAAAYEAKAFVDELVP 543
++ MG AEN + +ITR+ QD +A+ S +R+ AA A F DE+VP
Sbjct: 200 ALFPLEAMGETAENIVGRSREGAYAGGEITREQQDAFALESQRRAVAAINAGKFKDEIVP 259
Query: 544 VPVPQKRGAPV 576
V + ++G V
Sbjct: 260 VEIKGRKGVTV 270
>UniRef50_Q8IKW7 Cluster: Acetyl-CoA acetyltransferase, putative;
n=6; Plasmodium|Rep: Acetyl-CoA acetyltransferase,
putative - Plasmodium falciparum (isolate 3D7)
Length = 398
Score = 89.8 bits (213), Expect = 4e-17
Identities = 58/174 (33%), Positives = 82/174 (47%), Gaps = 5/174 (2%)
Frame = +1
Query: 58 IEXAGIPKXXIKXVYIGNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIML 237
+E + I K I + G S+ G P + I G+ +T VN +C SG+ SI +
Sbjct: 43 LERSQIEKEHIDCLIFGQSFSSGCGPVPLQKIAISTGMHINTKTYLVNNLCCSGLDSITI 102
Query: 238 AAQGLQTGAQDIILAGGMESMSNVPFYLKRGET---SYGGMQLVDGIVFDGLTDVYNKFH 408
L G +D + G ME MS P++LK T S G L D I+ DG + N
Sbjct: 103 GYD-LIRGGKDTCVVGSMECMSQSPYFLKNLRTEKYSLGNNILRDSIIHDGYDFMVNNKE 161
Query: 409 M--GNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPVPQKR 564
+ N E KK I R D DEY +NS+KR+A AY EL P+ + + +
Sbjct: 162 LKTNNSMELFCKKYNIPRVDLDEYVINSFKRTANAYSENLIQQELFPLVIQKNK 215
>UniRef50_Q9YA31 Cluster: Acetyl-CoA acetyltransferase; n=1;
Aeropyrum pernix|Rep: Acetyl-CoA acetyltransferase -
Aeropyrum pernix
Length = 402
Score = 88.2 bits (209), Expect = 1e-16
Identities = 60/169 (35%), Positives = 85/169 (50%), Gaps = 6/169 (3%)
Frame = +1
Query: 58 IEXAGIPKXXIKXVYIGNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIML 237
+E AG+ I+ G+V A A QA + AGL V+ VCASGM S++
Sbjct: 47 LERAGVDPNYIELAVYGHVIRAGTHMNTAKQAALKAGLRSDLEGFNVDMVCASGMASVVK 106
Query: 238 AAQGLQTGAQDIILAGGMESMSNVPFY----LKRG-ETSY-GGMQLVDGIVFDGLTDVYN 399
A+ + G + LAGGMESMSN PF ++ G Y G +++ D +V DGL D N
Sbjct: 107 ASLLIDAGMYSLALAGGMESMSNAPFIAPPSIRWGVRLLYQGALEMKDAMVSDGLYDPLN 166
Query: 400 KFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPV 546
+ MG A+ TA + R++ D A S R+A A+E +PV
Sbjct: 167 QLVMGQEADETAWEYGAQREELDWIAYESNMRAARAWERGHMQKYTIPV 215
>UniRef50_Q21BM7 Cluster: Acetyl-CoA C-acetyltransferase; n=1;
Rhodopseudomonas palustris BisB18|Rep: Acetyl-CoA
C-acetyltransferase - Rhodopseudomonas palustris (strain
BisB18)
Length = 389
Score = 85.4 bits (202), Expect = 9e-16
Identities = 52/179 (29%), Positives = 90/179 (50%)
Frame = +1
Query: 58 IEXAGIPKXXIKXVYIGNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIML 237
+ A I I V N+ + + A + AGLP S T+++ CA+ + ++
Sbjct: 38 VRRAEIDPERIDDVVFANLMNNEINNM-GRMAALEAGLPVSVGGITLDRQCAASLNALAY 96
Query: 238 AAQGLQTGAQDIILAGGMESMSNVPFYLKRGETSYGGMQLVDGIVFDGLTDVYNKFHMGN 417
A + G D+I+AGG+ES S + +++ E +Y + + D MG
Sbjct: 97 GAMQIMAGFADVIVAGGVESDSRRTYSMEKSEIAYS-VAPPKWVDIHTSPDSIGNPPMGI 155
Query: 418 CAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPVPQKRGAPVIFAEXE 594
AEN A++ ++TRQ+ DE++V S+ ++AA+EA F DE+VP+ V +G + E
Sbjct: 156 TAENVAERWKLTRQELDEFSVRSHVLASAAWEAGRFQDEVVPIEVKGPKGKKTVVDRDE 214
>UniRef50_A7AWF2 Cluster: Thiolase, N-terminal and C-terminal domain
containing protein; n=1; Babesia bovis|Rep: Thiolase,
N-terminal and C-terminal domain containing protein -
Babesia bovis
Length = 381
Score = 83.8 bits (198), Expect = 3e-15
Identities = 48/159 (30%), Positives = 81/159 (50%), Gaps = 1/159 (0%)
Frame = +1
Query: 88 IKXVYIGNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQ 267
I + + V + G +P+ Q AGLP +T C +N +C SG+KS+ +A G+ G
Sbjct: 46 IDTLVLSQVITGGTGPSPSRQISKGAGLPNTTKCMQINHLCTSGLKSVTIATDGIALGKS 105
Query: 268 DIILAGGMESMSNVPFYLKRGETSYGGMQLVDGIVFDGLT-DVYNKFHMGNCAENTAKKL 444
+ G+ES S P+ L + GG L DG++ D LT D ++ M + K +
Sbjct: 106 QLTAVVGVESSSQSPYLLTKARE--GGYGLGDGVLVDPLTSDGFSSPCMD--PDTFLKHV 161
Query: 445 QITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPVPQK 561
+IT + +Y ++++AA Y +E++PV V +K
Sbjct: 162 KITNAELSQYVQEMFQQTAACYSDGIMQNEIIPVVVNRK 200
>UniRef50_Q0EXX9 Cluster: Acetyl-CoA acyltransferase; n=2;
Proteobacteria|Rep: Acetyl-CoA acyltransferase -
Mariprofundus ferrooxydans PV-1
Length = 466
Score = 59.3 bits (137), Expect(2) = 3e-15
Identities = 30/75 (40%), Positives = 45/75 (60%)
Frame = +1
Query: 88 IKXVYIGNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQ 267
I V +GNV A + AG+P+ TV++ CASGM++I AA+ +Q G
Sbjct: 87 IDQVILGNVIQPAEASNIARVIALTAGVPQQVPAHTVHRNCASGMQAITDAAEKIQLGRA 146
Query: 268 DIILAGGMESMSNVP 312
D++LAGG+ESM++ P
Sbjct: 147 DVVLAGGVESMTHAP 161
Score = 44.8 bits (101), Expect(2) = 3e-15
Identities = 23/62 (37%), Positives = 37/62 (59%)
Frame = +1
Query: 370 VFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVP 549
+ +GLTD MG AE A++ +TR +QD YA+ S++R+AA + F DE++ +
Sbjct: 202 LLEGLTDPTVGMGMGQTAELLAREFGVTRAEQDAYALMSHQRAAAGWSDGWFDDEVMHLF 261
Query: 550 VP 555
P
Sbjct: 262 AP 263
>UniRef50_Q0LKV2 Cluster: Acetyl-CoA C-acyltransferase; n=2;
cellular organisms|Rep: Acetyl-CoA C-acyltransferase -
Herpetosiphon aurantiacus ATCC 23779
Length = 384
Score = 83.0 bits (196), Expect = 5e-15
Identities = 55/175 (31%), Positives = 85/175 (48%), Gaps = 3/175 (1%)
Frame = +1
Query: 58 IEXAGIPKXXIKXVYIGNVCSANLGQAPAX---QAVIFAGLPKSTICTTVNKVCASGMKS 228
IE GI I+ V G C N G+ A V+ + LP + T+N++C S ++
Sbjct: 38 IERTGIDPNLIEDVVTG--CVTNTGEQGANIGRLGVMLSNLPITVPAVTLNRMCGSAQQA 95
Query: 229 IMLAAQGLQTGAQDIILAGGMESMSNVPFYLKRGETSYGGMQLVDGIVFDGLTDVYNKFH 408
I AAQ + G +AGG+ESMS VP + G + + + Y H
Sbjct: 96 IHFAAQAIAAGDVSYAIAGGVESMSRVPMF----SDVTGNFATFN----PAINEKYQLVH 147
Query: 409 MGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPVPQKRGAP 573
G AE A+K Q++R + D+++ S++R+AAA +A F +L P+ K G P
Sbjct: 148 QGESAELIAEKYQLSRTELDDWSFESHQRAAAATKAGWFSSQLAPIVGSDKTGNP 202
>UniRef50_Q2QAP2 Cluster: Acetyl-CoA acetyltransferase; n=2;
environmental samples|Rep: Acetyl-CoA acetyltransferase
- uncultured marine group II euryarchaeote HF70_59C08
Length = 406
Score = 82.2 bits (194), Expect = 8e-15
Identities = 49/145 (33%), Positives = 78/145 (53%), Gaps = 10/145 (6%)
Frame = +1
Query: 142 AXQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPFYL 321
A A + AG+P+ TV+++C SG++SI+ AAQ +Q G ++AGGME+MS P L
Sbjct: 78 ARHAGLGAGIPQEVPMLTVSRICGSGVQSIVNAAQMIQLGEAATVVAGGMENMSQAPHVL 137
Query: 322 -------KRGETSYGGMQL---VDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDE 471
+ G G +L ++ +F L D M ++ K+ +TR++ DE
Sbjct: 138 RGMRDTFRLGRPPQAGTELPKDMEDYLFTNLLDGMCGSFMAQTSDEICKRKGVTREETDE 197
Query: 472 YAVNSYKRSAAAYEAKAFVDELVPV 546
+A S+ R+AA+ E F E+VPV
Sbjct: 198 FAAMSHARTAASIENNIFEQEIVPV 222
>UniRef50_A1SXV9 Cluster: Acetyl-CoA acetyltransferases; n=1;
Psychromonas ingrahamii 37|Rep: Acetyl-CoA
acetyltransferases - Psychromonas ingrahamii (strain 37)
Length = 437
Score = 81.8 bits (193), Expect = 1e-14
Identities = 62/187 (33%), Positives = 91/187 (48%), Gaps = 26/187 (13%)
Frame = +1
Query: 73 IPKXXIKXVYIGNVCSANLGQ---APAXQAVIF--AGLPKSTICTTVNKVCASGMKSIML 237
I + I I + N+GQ AP VI AGLP I TV++ CASGM+S+
Sbjct: 47 IARTEIDLKLIDELIFGNVGQPANAPNIARVIALKAGLPLEVIAHTVHRNCASGMESVTT 106
Query: 238 AAQGLQTGAQDIILAGGMESMSNVPF-YLKRGETSYGGMQLVDGI--------------- 369
L G +I++AGG ESMSN+PF + K+ + + I
Sbjct: 107 GYDKLLAGNANILIAGGTESMSNLPFNFSKKMTQVFENVMKAKSIGQKLSAISTLRPADL 166
Query: 370 -----VFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDE 534
+ +GLTD MG AE A++ ITR +QD++A+ S+ ++A A EA F E
Sbjct: 167 KPVISIVEGLTDPVCGLSMGQTAEVLAREFAITRAEQDQFALQSHLKAAKANEAGFFTQE 226
Query: 535 LVPVPVP 555
+ P+ +P
Sbjct: 227 IHPIMLP 233
>UniRef50_A3LMS9 Cluster: Acetyl-CoA C-acyltransferase, peroxisomal;
n=3; Saccharomycetales|Rep: Acetyl-CoA
C-acyltransferase, peroxisomal - Pichia stipitis (Yeast)
Length = 404
Score = 81.4 bits (192), Expect = 1e-14
Identities = 52/179 (29%), Positives = 87/179 (48%), Gaps = 2/179 (1%)
Frame = +1
Query: 58 IEXAGIPKXXIKXVYIGNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIML 237
IE +G+ I + +G V GQ + A G P T T+N+ CAS +++
Sbjct: 50 IERSGVDPELIDDILVGAVLQTLGGQKASALAAKKVGFPVKTTVNTINRQCASSAQAVSY 109
Query: 238 AAQGLQTGAQDIILAGGMESMSNVPFYLKRGETSYGGMQLVDGIVFDGLTDVYN-KFHMG 414
+A L TG +A G+ESM++ ++ RG + ++ + + + N MG
Sbjct: 110 SAGSLITGENQFTIAAGVESMTH-DYFPHRGIPT----RIYEPFRQEASAEAQNVLMPMG 164
Query: 415 NCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPV-PQKRGAPVIFAE 588
+EN A ITR+DQD +AV S+ ++A A E+ F E++P+ G P+ A+
Sbjct: 165 ITSENVANDFGITREDQDRFAVQSHLKAAKATESGHFAKEIIPINARTNAEGEPIAHAQ 223
>UniRef50_Q9RUF8 Cluster: Acetyl-CoA acetyltransferase; n=144;
cellular organisms|Rep: Acetyl-CoA acetyltransferase -
Deinococcus radiodurans
Length = 402
Score = 80.6 bits (190), Expect = 3e-14
Identities = 60/170 (35%), Positives = 87/170 (51%), Gaps = 2/170 (1%)
Frame = +1
Query: 58 IEXAGIPKXXIKXVYIG--NVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSI 231
IE AG+ I+ V +G N A G A Q + AGLP + TVN+ C+SG+ +I
Sbjct: 48 IERAGVNPADIEDVIMGAGNPEGAT-GSNIARQIALRAGLPVTVSGVTVNRFCSSGLNTI 106
Query: 232 MLAAQGLQTGAQDIILAGGMESMSNVPFYLKRGETSYGGMQLVDGIVFDGLTDVYNKFHM 411
LAA + G D+ +AGG+ES+S L + E + L + + D+Y M
Sbjct: 107 ALAANHVMAGQGDVFVAGGLESIS-----LTQNEHA-NTFHLRGEWLLEHKPDIY--MSM 158
Query: 412 GNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPVPQK 561
AE A++ I+R+ QDEY S R+AAA +A F E+VP+ K
Sbjct: 159 LQTAEVVAERYGISRERQDEYGYQSQMRTAAAQQAGKFDHEIVPMTATMK 208
>UniRef50_Q8KXD4 Cluster: Beta-ketothiolase; n=11;
Proteobacteria|Rep: Beta-ketothiolase - Azospirillum
brasilense
Length = 387
Score = 80.6 bits (190), Expect = 3e-14
Identities = 54/166 (32%), Positives = 83/166 (50%), Gaps = 3/166 (1%)
Frame = +1
Query: 58 IEXAGIPKXXIKXVYIGNVC-SANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIM 234
+E G+ I+ V +G G A A LP + TT+N+ C S M++I
Sbjct: 48 VERTGVNPQDIEDVVVGCAFPEGEQGMNIARTVSFLAKLPLTAGATTINRYCGSSMQAIH 107
Query: 235 LAAQGLQTGAQDIILAGGMESMSNVPFYLKRGETSYGGMQLVDGIVFDGLTDVYNKFH-- 408
AA +Q GA ++ L GG+ESMS VP M + + GL D Y + +
Sbjct: 108 QAAGAIQMGAGEVFLCGGIESMSRVP------------MMGYNPLPHPGLKDHYPEAYCS 155
Query: 409 MGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPV 546
MG AEN A++ +I+R DQ+ A S+ ++AAA +A +E+V +
Sbjct: 156 MGVTAENVARRYEISRADQEAMAAESHAKAAAAQQAGRLAEEIVAI 201
>UniRef50_Q7NUH9 Cluster: Acetyl-CoA C-acyltransferase; n=51;
Bacteria|Rep: Acetyl-CoA C-acyltransferase -
Chromobacterium violaceum
Length = 400
Score = 80.2 bits (189), Expect = 3e-14
Identities = 46/144 (31%), Positives = 78/144 (54%)
Frame = +1
Query: 121 ANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESM 300
A G A V+ AGLP + T+N+ C+SG+ ++ +AA ++ G D+++A G ESM
Sbjct: 66 AEQGLNMARIGVLLAGLPNTVGGITINRYCSSGINAVQMAADRIRLGEADVVIAAGSESM 125
Query: 301 SNVPFYLKRGETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAV 480
S VP G ++ +F + + MG AE A++ ++R+DQD +AV
Sbjct: 126 SLVPM--------MGNKVSLNPEIFAKDENYGIAYGMGLTAEKVAQQWGVSREDQDAFAV 177
Query: 481 NSYKRSAAAYEAKAFVDELVPVPV 552
S++R+ AA + F +E+ P+ V
Sbjct: 178 ESHRRALAAIDGGKFKNEITPLEV 201
>UniRef50_Q8SVA6 Cluster: Similarity to 3-KETOACYL COA THIOLASE;
n=1; Encephalitozoon cuniculi|Rep: Similarity to
3-KETOACYL COA THIOLASE - Encephalitozoon cuniculi
Length = 391
Score = 79.4 bits (187), Expect = 6e-14
Identities = 54/165 (32%), Positives = 86/165 (52%)
Frame = +1
Query: 58 IEXAGIPKXXIKXVYIGNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIML 237
IE GI I+ V +G+ S+ G A V+ AG+P T +N++C SG++S+ L
Sbjct: 42 IEKTGIDPRLIEEVILGHCLSSMEGNVAARMGVLRAGVPVETPVMIINRLCGSGLESVGL 101
Query: 238 AAQGLQTGAQDIILAGGMESMSNVPFYLKRGETSYGGMQLVDGIVFDGLTDVYNKFHMGN 417
A+ +++G +I LAGG ESM++ + L + T L G + D +G
Sbjct: 102 IAEKIRSGRIEIGLAGGFESMTS--YGLPKEYT------LSRGGACEDAEDC--MLTLGE 151
Query: 418 CAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPV 552
+E K +TR + DEYAV S KR+ A + F+ E++P+ V
Sbjct: 152 VSEMLGKTHGVTRSEADEYAVTSQKRALEATKKGHFLAEIIPMRV 196
>UniRef50_Q9AA29 Cluster: Thiolase family protein; n=42;
Bacteria|Rep: Thiolase family protein - Caulobacter
crescentus (Caulobacter vibrioides)
Length = 390
Score = 79.0 bits (186), Expect = 8e-14
Identities = 59/199 (29%), Positives = 98/199 (49%), Gaps = 9/199 (4%)
Frame = +1
Query: 1 GRFSXFXXXXXXXXXXXXXIEXAGIPKXXIKXVYIGNVCSANLGQAP---AXQAVIFAGL 171
GR S + ++ +G I+ V +G C +G+ A AV+ + L
Sbjct: 19 GRVSGWHPADLAGEVLNALVDRSGADPALIEDVIMG--CVGQVGEQAINIARNAVLASKL 76
Query: 172 PKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPFYL------KRGE 333
P+S T+V++ C S +SI AA + +GA DI++A G+ESMS VP L K G
Sbjct: 77 PESVPATSVDRQCGSSQQSIHFAAATVMSGAMDIVIAAGVESMSRVPMGLSSALPYKNGF 136
Query: 334 TSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYE 513
+Y ++ + + G+ +F AE AKK ++R+ D +A+ S++R+ AA +
Sbjct: 137 GTYKSPRMEER--YPGI-----QFSQFAGAEMLAKKYDLSREQLDAFALASHQRAMAATK 189
Query: 514 AKAFVDELVPVPVPQKRGA 570
F E+VP+ V G+
Sbjct: 190 GGKFAAEIVPIKVTLPDGS 208
>UniRef50_A5UWB8 Cluster: Acetyl-CoA acetyltransferase; n=3;
Bacteria|Rep: Acetyl-CoA acetyltransferase - Roseiflexus
sp. RS-1
Length = 385
Score = 78.6 bits (185), Expect = 1e-13
Identities = 53/161 (32%), Positives = 83/161 (51%), Gaps = 2/161 (1%)
Frame = +1
Query: 70 GIPKXXIKXVYIGNVCSANLGQAP-AXQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQ 246
G+ I V G V + A A A + AGLP+S TT+++ C S +++I AAQ
Sbjct: 42 GVDPAAIDDVIAGCVSQSGEQSANIARNAWLAAGLPESVPATTIDRQCGSSLQAIHFAAQ 101
Query: 247 GLQTGAQDIILAGGMESMSNVPFYLKRGETSYGGMQLVDGIVFD-GLTDVYNKFHMGNCA 423
G+ G D+++A G+ESM+ VP + G L G+ GL + F A
Sbjct: 102 GVMAGVYDLVIAAGVESMTRVP--IGASIMVGPGTPLSPGLATRYGLERGW--FDQARGA 157
Query: 424 ENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPV 546
E A++ + TR+D D Y++ S++ +A A A F E++PV
Sbjct: 158 EWMAREWRFTREDLDRYSLRSHRLAAEARAAGRFTAEIIPV 198
>UniRef50_Q39N04 Cluster: Acetyl-CoA C-acetyltransferase; n=29;
Bacteria|Rep: Acetyl-CoA C-acetyltransferase -
Burkholderia sp. (strain 383) (Burkholderia cepacia
(strain ATCC 17760/ NCIB 9086 / R18194))
Length = 423
Score = 78.2 bits (184), Expect = 1e-13
Identities = 54/167 (32%), Positives = 82/167 (49%), Gaps = 7/167 (4%)
Frame = +1
Query: 88 IKXVYIGNVCSANLGQ---APAXQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQT 258
+ V IG C + +G+ P A + AG P TT+ + C S ++I AAQ +
Sbjct: 77 VDDVMIG--CVSQVGEQSTTPGRVAWLAAGFPAHVPATTIERKCGSSQQAIHFAAQAIMA 134
Query: 259 GAQDIILAGGMESMSNVPFYLKR-GETSYGG---MQLVDGIVFDGLTDVYNKFHMGNCAE 426
G DI++AGG+ESMS VP R YG + G+V G++ A+
Sbjct: 135 GVNDIVIAGGVESMSRVPMGSARIDRDPYGARFHARFPQGLVGQGVS-----------AD 183
Query: 427 NTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPVPQKRG 567
A+K ++R+ D Y+ S++R+ AA A F E+VP+ VP G
Sbjct: 184 LVAQKWDLSREALDAYSAESHRRAEAARTAGQFAREIVPIDVPGDGG 230
>UniRef50_A0JWS0 Cluster: Acetyl-CoA acetyltransferases; n=2;
Arthrobacter|Rep: Acetyl-CoA acetyltransferases -
Arthrobacter sp. (strain FB24)
Length = 399
Score = 78.2 bits (184), Expect = 1e-13
Identities = 52/159 (32%), Positives = 80/159 (50%)
Frame = +1
Query: 70 GIPKXXIKXVYIGNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQG 249
G+P + V +GN G A A + AGLP S TV++ C SG+ +I+LA++
Sbjct: 50 GLPANAVSDVVVGNAVGG--GGNVARLAALEAGLPVSVPGVTVDRQCGSGLDAIVLASRL 107
Query: 250 LQTGAQDIILAGGMESMSNVPFYLKRGETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAEN 429
+ G LAGG+ES+S P L+ ++ G F L+ + MG AEN
Sbjct: 108 VAAGGNGAFLAGGVESISTAP--LRANRSADGSPAFFRRAQFVPLS--FGDPDMGCAAEN 163
Query: 430 TAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPV 546
A + I+R QD +A+ S++ + AA A + E VP+
Sbjct: 164 VAAEFGISRDRQDRFALRSHRLALAAAAAGRYSGETVPL 202
>UniRef50_A3Q406 Cluster: Acetyl-CoA acetyltransferases; n=22;
Actinomycetales|Rep: Acetyl-CoA acetyltransferases -
Mycobacterium sp. (strain JLS)
Length = 396
Score = 77.8 bits (183), Expect = 2e-13
Identities = 53/138 (38%), Positives = 72/138 (52%), Gaps = 5/138 (3%)
Frame = +1
Query: 196 VNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPFYLKRGETSYGGM--QLVDG- 366
VN+ CAS + +I + A + G ILAGGMES S P KR + G D
Sbjct: 86 VNRQCASSLSAIAVGAGQIAAGMSRAILAGGMESCSTTPLLRKRKPFTTGKSPEDYQDPW 145
Query: 367 IVFDGL-TDVYNKFHMG-NCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELV 540
F T+ M A N A + I+R+ QDE+A+ S++R+ A +A +FVDE+V
Sbjct: 146 FPFSHPPTEDAPALDMSITVAHNCAVQYGISREAQDEWALRSHQRAVKAIDAGSFVDEIV 205
Query: 541 PVPVPQKRGAPVIFAEXE 594
PV VPQ G + FAE E
Sbjct: 206 PVEVPQADGGTITFAEDE 223
>UniRef50_Q8NN21 Cluster: Acetyl-CoA acetyltransferases; n=9;
Corynebacterineae|Rep: Acetyl-CoA acetyltransferases -
Corynebacterium glutamicum (Brevibacterium flavum)
Length = 408
Score = 77.0 bits (181), Expect = 3e-13
Identities = 63/191 (32%), Positives = 99/191 (51%), Gaps = 12/191 (6%)
Frame = +1
Query: 58 IEXAGIPKXXIKXVYIGNVCSANLGQAPAXQAVIF--AGLPKSTICTTVNKVCASGMKSI 231
+E GI + + +G S N G APA V+ + L ++ +++ C SG+++I
Sbjct: 40 VEATGITGDDVDDLILGQA-SPN-GAAPALGRVVALDSKLGQNVPGMQLDRRCGSGLQAI 97
Query: 232 MLAAQGLQTGAQDIILAGGMESMSNVPFYLK---RGETSYGGMQLVDGIVFDGLTDVYNK 402
+ AA + +GA D+I+AGG ESMS V + + R G MQL D + + +
Sbjct: 98 VTAAAHVASGAADLIIAGGAESMSRVEYTVSGDIRWGVKGGDMQLRDRLA-EARETAGGR 156
Query: 403 FH-----MGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPVP-QKR 564
H M AEN ++ I+R++QD+ + S +R A +A F DE+VPV VP +KR
Sbjct: 157 NHPIPGGMIETAENLRREYGISREEQDKISAASQQRWGKAADAGLFDDEIVPVTVPAKKR 216
Query: 565 G-APVIFAEXE 594
G P I + E
Sbjct: 217 GQEPTIVSRDE 227
>UniRef50_Q2UTB1 Cluster: RIB40 genomic DNA, SC005; n=6;
Ascomycota|Rep: RIB40 genomic DNA, SC005 - Aspergillus
oryzae
Length = 413
Score = 77.0 bits (181), Expect = 3e-13
Identities = 52/153 (33%), Positives = 78/153 (50%)
Frame = +1
Query: 88 IKXVYIGNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQ 267
I+ V IG+V G A I AG P + T+N+ C+SG+ +I G++ GA
Sbjct: 66 IEEVAIGSVLQELGGAKAGRMAQIHAGFPHTVPFHTINRQCSSGLAAITAIGNGIRAGAL 125
Query: 268 DIILAGGMESMSNVPFYLKRGETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQ 447
+I + GGMESM+ Y R + +L + D + MG +EN A +
Sbjct: 126 NIGVGGGMESMTR--NYGFRAIPTVLWPELKESPSKDSRDCI---MPMGITSENVASRYG 180
Query: 448 ITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPV 546
I+R+DQD +A S+K++ AA A F E+VPV
Sbjct: 181 ISREDQDVFAAESHKKATAAQNAGLFDSEIVPV 213
>UniRef50_Q2J8N8 Cluster: Acetyl-CoA C-acyltransferase; n=64;
Bacteria|Rep: Acetyl-CoA C-acyltransferase - Frankia sp.
(strain CcI3)
Length = 397
Score = 76.6 bits (180), Expect = 4e-13
Identities = 50/138 (36%), Positives = 76/138 (55%), Gaps = 4/138 (2%)
Frame = +1
Query: 151 AVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPFYLKRG 330
AV+ AG P+S TT+++ C S ++ AAQG+ GA DI++A G+ESMS VP G
Sbjct: 72 AVLSAGFPESVPATTIDRQCGSSQQAAHFAAQGVLAGAYDIVIAAGVESMSRVPM----G 127
Query: 331 ETSYG----GMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRS 498
T++G G L +GL H G AE + + +I R+D D ++ S++ +
Sbjct: 128 STTFGKDPNGPSL-HARYPEGLA------HQGIGAELVSARWKINREDLDIFSARSHQLA 180
Query: 499 AAAYEAKAFVDELVPVPV 552
AA+ A F E+VPV +
Sbjct: 181 AASVAAGDFAGEIVPVEI 198
>UniRef50_Q128L5 Cluster: Acetyl-CoA C-acyltransferase; n=13;
Proteobacteria|Rep: Acetyl-CoA C-acyltransferase -
Polaromonas sp. (strain JS666 / ATCC BAA-500)
Length = 416
Score = 76.6 bits (180), Expect = 4e-13
Identities = 47/166 (28%), Positives = 79/166 (47%), Gaps = 3/166 (1%)
Frame = +1
Query: 58 IEXAGIPKXXIKXVYIGNVCSANLGQAPAXQAV-IFAGLPKSTICTTVNKVCASGMKSIM 234
+E +G+P I V GN+ + Q + + ++AG+P ++C +G +
Sbjct: 47 LERSGVPAAHIGSVIAGNMAPGDFDQFMLPRHIGLYAGVPLEVPALMAQRICGTGFELFR 106
Query: 235 LAAQGLQTGAQDIILAGGMESMSNVPFYLKRGETSY--GGMQLVDGIVFDGLTDVYNKFH 408
A + +Q+GA + L G ESM+ P T + G +++ L D +
Sbjct: 107 QAGEHIQSGACEAALVVGAESMTRNPIAAFDHRTGFKLGAPVGFKDYMWEALKDSAAGIN 166
Query: 409 MGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPV 546
M AEN AKK +TR+ DE+A S+ R+ AA ++ E+VPV
Sbjct: 167 MIQTAENLAKKYGVTREQVDEFASQSFARAVAAQQSGFHAGEIVPV 212
>UniRef50_Q5P0L6 Cluster: Putative beta-ketothiolase; n=2;
Azoarcus|Rep: Putative beta-ketothiolase - Azoarcus sp.
(strain EbN1) (Aromatoleum aromaticum (strain EbN1))
Length = 421
Score = 75.4 bits (177), Expect = 1e-12
Identities = 47/165 (28%), Positives = 81/165 (49%), Gaps = 3/165 (1%)
Frame = +1
Query: 61 EXAGIPKXXIKXVYIGNVCSANLGQAPAXQAV-IFAGLPKSTICTTVNKVCASGMKSIML 237
+ +GIP I + GN+ A+ + + +++G+ + V ++C +G ++I+
Sbjct: 57 DRSGIPASEIDAIVAGNMAQASFDAYFLPRHIGLYSGVNPNVPALLVQRLCGTGFETIIA 116
Query: 238 AAQGLQTGAQDIILAGGMESMSNVPF--YLKRGETSYGGMQLVDGIVFDGLTDVYNKFHM 411
AA + G + LA G ESMS P Y R G + D +++ D M
Sbjct: 117 AADQITLGKAKVALAVGTESMSRNPIAAYTHRAGFRMGQLDFRD-FLWEATKDTAPGASM 175
Query: 412 GNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPV 546
G+ AEN AK+ I+R + D +A S+ + AA+E+ F E+ PV
Sbjct: 176 GDTAENLAKRYGISRGEVDRFAEQSFAHACAAWESGWFAGEVAPV 220
>UniRef50_Q0LZF8 Cluster: Acetyl-CoA C-acetyltransferase; n=3;
Bacteria|Rep: Acetyl-CoA C-acetyltransferase -
Caulobacter sp. K31
Length = 395
Score = 75.4 bits (177), Expect = 1e-12
Identities = 55/169 (32%), Positives = 81/169 (47%), Gaps = 4/169 (2%)
Frame = +1
Query: 58 IEXAGIPKXXIKXVYIGNVCSANLGQAPAXQA---VIFAGLPKSTICTTVNKVCASGMKS 228
+ AG+ I V G C +G+ A A ++ AG P++ TV++ C S +
Sbjct: 38 VARAGVGAEHIDDVIFG--CVTQVGEQSANIARTSLLGAGWPETIGAMTVDRKCGSSEAA 95
Query: 229 IMLAAQGLQTGAQDIILAGGMESMSNVPFYLKRGETSYGGMQLVDGIVFDGL-TDVYNKF 405
I +AA + G D+++AGG ESMS VP G + + G F + +D Y
Sbjct: 96 IHIAAAQIAAGLSDLVVAGGAESMSRVPM---------GSNRSIHGEAFGWMVSDRYELT 146
Query: 406 HMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPV 552
G AE A K R D++A S++R+AAA +A F E V VPV
Sbjct: 147 SQGEAAERIADKYGFDRDALDDFAAESHRRAAAATDAGYFRAETVAVPV 195
>UniRef50_P21775-2 Cluster: Isoform 2 of P21775 ; n=4;
Euarchontoglires|Rep: Isoform 2 of P21775 - Rattus
norvegicus (Rat)
Length = 373
Score = 74.9 bits (176), Expect = 1e-12
Identities = 48/150 (32%), Positives = 80/150 (53%)
Frame = +1
Query: 97 VYIGNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDII 276
+ +GNV G A A +G+P++ + VN+ C+SG++++ A G++ G+ DI
Sbjct: 86 ISVGNVLEPGAGAVMARIAQFLSGIPETVPLSAVNRQCSSGLQAVANIAGGIRNGSYDIG 145
Query: 277 LAGGMESMSNVPFYLKRGETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITR 456
+A G+ESMS RG +L++ D D MG +EN A++ I+R
Sbjct: 146 MACGVESMS----LSNRGNPGNISSRLLES---DKARDCL--IPMGITSENVAERFGISR 196
Query: 457 QDQDEYAVNSYKRSAAAYEAKAFVDELVPV 546
Q QD +A+ S +++A+A F E+VPV
Sbjct: 197 QKQDAFALASQQKAASAQSKGCFRAEIVPV 226
>UniRef50_Q8EN18 Cluster: Beta-ketothiolase; n=4; Bacteria|Rep:
Beta-ketothiolase - Oceanobacillus iheyensis
Length = 383
Score = 74.9 bits (176), Expect = 1e-12
Identities = 51/174 (29%), Positives = 86/174 (49%), Gaps = 1/174 (0%)
Frame = +1
Query: 58 IEXAGIPKXXIKXVYIGNVC-SANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIM 234
+ G+ I+ V +G V S QA + AG P TT+++ C S ++I
Sbjct: 38 VTRTGLDSGLIEDVIMGCVTQSGEQAFDIGRQAALIAGYPIEVPGTTIDRQCGSSQQAIH 97
Query: 235 LAAQGLQTGAQDIILAGGMESMSNVPFYLKRGETSYGGMQLVDGIVFDGLTDVYNKFHMG 414
AAQ + +G DI++A G+ESMS VP ++ G++L LT Y + G
Sbjct: 98 FAAQAILSGDMDIVVAAGIESMSRVPM-----GSNQQGVKL-----SKSLTTKYEIINQG 147
Query: 415 NCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPVPQKRGAPV 576
AE AK+ I+R++ D +A+ S++++ A F ++L+ V + + G V
Sbjct: 148 LSAERIAKQWNISREEMDVFALESHQKAIEARNNGYFTEQLMSVEITRADGTKV 201
>UniRef50_Q39TD0 Cluster: Thiolase; n=1; Geobacter metallireducens
GS-15|Rep: Thiolase - Geobacter metallireducens (strain
GS-15 / ATCC 53774 / DSM 7210)
Length = 409
Score = 74.9 bits (176), Expect = 1e-12
Identities = 56/187 (29%), Positives = 90/187 (48%), Gaps = 8/187 (4%)
Frame = +1
Query: 58 IEXAGIPKXXIKXVYIGNVCSANLG---QAPAXQAVIFAGLPKSTICTTVNKVCASGMKS 228
++ +G+ I VY G + A QA++ AGLP T+ TV++ C S + +
Sbjct: 41 LQRSGLKGSDIDEVYYGMCIQSEAALKYNVVARQAMLHAGLPPETLSLTVDRACCSSLAA 100
Query: 229 IMLAAQGLQTGAQDIILAGGMESMSNVPFYLK--RGETSYGGMQLVDGIVFDGLTDVYNK 402
+ L + L + +A G E+MSN P L R T G ++VD + +Y
Sbjct: 101 VQLGRKSLLLDEAKVCMAVGAENMSNTPVVLNGHRWGTGLGKPEMVDHL----NPIMYVG 156
Query: 403 FH-MGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAF--VDELVPVPVPQKRGAP 573
F+ + A A + ++R+ QD +A S + AA A F +E+ + + QK+G P
Sbjct: 157 FNSLAGDAGAVALEYDVSREMQDAWAYASQMKYQAAKAAGKFRPGEEVAAIELSQKKGDP 216
Query: 574 VIFAEXE 594
VIFAE E
Sbjct: 217 VIFAEDE 223
>UniRef50_A1SFE7 Cluster: Acetyl-CoA acetyltransferases; n=11;
Bacteria|Rep: Acetyl-CoA acetyltransferases -
Nocardioides sp. (strain BAA-499 / JS614)
Length = 404
Score = 74.9 bits (176), Expect = 1e-12
Identities = 41/138 (29%), Positives = 78/138 (56%), Gaps = 6/138 (4%)
Frame = +1
Query: 151 AVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPFYLKRG 330
AV+ AGLP S T+N++C S + + + ++ +++G +++L GG+ESMS P+ L +
Sbjct: 72 AVLLAGLPVSVPAVTLNRLCGSSLDAAIAGSRSIESGDAEVVLTGGVESMSRAPWVLPKP 131
Query: 331 ETSY--GGMQLVDGIVFDGLTD----VYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYK 492
E +Y G + V + L + +G E A++ +++R+ QDE+A S++
Sbjct: 132 ERAYPAGNVTAVSTTLGWRLVNERMPAEWTVSLGEANELLAERFEVSRERQDEFAARSHR 191
Query: 493 RSAAAYEAKAFVDELVPV 546
+ AA+ + + D +VPV
Sbjct: 192 LADAAWTSGFYDDLVVPV 209
>UniRef50_A0E400 Cluster: Chromosome undetermined scaffold_77, whole
genome shotgun sequence; n=3; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_77,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 412
Score = 74.5 bits (175), Expect = 2e-12
Identities = 44/170 (25%), Positives = 83/170 (48%)
Frame = +1
Query: 58 IEXAGIPKXXIKXVYIGNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIML 237
+E + I+ + +GNV G + A +G P +T T +N+ C+SG+++ +
Sbjct: 60 LERTKVDPKLIQDIVVGNVNQPGSGAIVSKMAAFLSGFPDTTCLTAINRFCSSGIEACAV 119
Query: 238 AAQGLQTGAQDIILAGGMESMSNVPFYLKRGETSYGGMQLVDGIVFDGLTDVYNKFHMGN 417
A +++G DI + G+E M+ Y + + + +L+ +FD MG
Sbjct: 120 IAAKIRSGMLDIGIGAGVEQMT---MYDMQSQMN---AELLSDAIFDHPCARDCLLGMGQ 173
Query: 418 CAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPVPQKRG 567
+EN A + +TR QD++A S +++ A + + DE++PV K G
Sbjct: 174 TSENVAAQFGVTRLQQDKFAYESQQKAYKAQQEGLYKDEIIPVKTFIKDG 223
>UniRef50_UPI000038DFAF Cluster: hypothetical protein Faci_03001535;
n=1; Ferroplasma acidarmanus fer1|Rep: hypothetical
protein Faci_03001535 - Ferroplasma acidarmanus fer1
Length = 391
Score = 74.1 bits (174), Expect = 2e-12
Identities = 43/133 (32%), Positives = 73/133 (54%)
Frame = +1
Query: 154 VIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPFYLKRGE 333
V+ A LP S ++++ C+S + + + A + G II++GGME M++VP + +
Sbjct: 77 VLLADLPVSVPAMSLDRACSSSLNATGIGALEIMAGKAGIIISGGMEHMTHVPLGVDN-Q 135
Query: 334 TSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYE 513
M+L+ + ++ ++MG AE AK I+R + DEY+ NS+KR+A AYE
Sbjct: 136 FIKPNMELMANPKYSKF-NMNVSYNMGLTAEKLAKLRNISRDEMDEYSYNSHKRAAKAYE 194
Query: 514 AKAFVDELVPVPV 552
E++PV V
Sbjct: 195 DGFMKGEIMPVTV 207
>UniRef50_P27796 Cluster: 3-ketoacyl-CoA thiolase, peroxisomal
precursor; n=13; Ascomycota|Rep: 3-ketoacyl-CoA
thiolase, peroxisomal precursor - Saccharomyces
cerevisiae (Baker's yeast)
Length = 417
Score = 73.7 bits (173), Expect = 3e-12
Identities = 47/157 (29%), Positives = 78/157 (49%), Gaps = 1/157 (0%)
Frame = +1
Query: 88 IKXVYIGNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQ 267
I+ V GNV + G A + +G+P ST +N+ C+SG+ ++ A ++ G
Sbjct: 85 IEEVACGNVLNVGAGATEHRAACLASGIPYSTPFVALNRQCSSGLTAVNDIANKIKVGQI 144
Query: 268 DIILAGGMESMSNVPFYLKRGETSYGGMQLVDGIVFDGLTDVYN-KFHMGNCAENTAKKL 444
DI LA G+ESM+N + + ++ + MG EN A
Sbjct: 145 DIGLALGVESMTN-------NYKNVNPLGMISSEELQKNREAKKCLIPMGITNENVAANF 197
Query: 445 QITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPVP 555
+I+R+DQDE+A NSY+++ A F DE++P+ +P
Sbjct: 198 KISRKDQDEFAANSYQKAYKAKNEGLFEDEILPIKLP 234
>UniRef50_Q5WL68 Cluster: Acetyl-CoA acetyltransferase; n=1;
Bacillus clausii KSM-K16|Rep: Acetyl-CoA
acetyltransferase - Bacillus clausii (strain KSM-K16)
Length = 394
Score = 72.5 bits (170), Expect = 7e-12
Identities = 54/163 (33%), Positives = 82/163 (50%), Gaps = 5/163 (3%)
Frame = +1
Query: 67 AGIPKXXIKXVYIGNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQ 246
AG+P I V +GN G A +++ +GLP TV+ C SG+++I++AA+
Sbjct: 39 AGLPFPEIDGVVLGNAVGE--GGNIARLSLLESGLPVDVPGVTVDVQCGSGLEAIIVAAR 96
Query: 247 GLQTGAQDIILAGGMESMSNVPFYLKRGETSYGG-----MQLVDGIVFDGLTDVYNKFHM 411
+Q G D+ LAGG+ES S P KR + G + ++ F + M
Sbjct: 97 HIQAGDGDVYLAGGVESTSLEP---KRIAANMNGNRREWHETIERARFS--PESLGDPDM 151
Query: 412 GNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELV 540
AEN A++ +I R QDEY SY+R+ AA + F DE +
Sbjct: 152 AEAAENVAEQRKIGRDAQDEYTAESYRRAWAAEQQGLFRDEKI 194
>UniRef50_A1IDF1 Cluster: Acetyl-CoA C-acyltransferase; n=1;
Candidatus Desulfococcus oleovorans Hxd3|Rep: Acetyl-CoA
C-acyltransferase - Candidatus Desulfococcus oleovorans
Hxd3
Length = 394
Score = 72.5 bits (170), Expect = 7e-12
Identities = 53/166 (31%), Positives = 82/166 (49%), Gaps = 3/166 (1%)
Frame = +1
Query: 61 EXAGIPKXXIKXVYIG-NVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIML 237
+ AG+ K + + +G + A G AV AG P TVN+ C+SG+++I L
Sbjct: 41 KTAGLEKKDVDDLMLGCSFPEAEQGLNIGRIAVQMAGFPDQVSGATVNRFCSSGLEAIAL 100
Query: 238 AAQGLQTGAQDIILAGGMESMSNVPF--YLKRGETSYGGMQLVDGIVFDGLTDVYNKFHM 411
A+ + +G D+ L GG+ESM+ VP L R + + D Y M
Sbjct: 101 ASLRVMSGWSDVTLGGGVESMTYVPMGGNLPRPHPEWSRER----------ADYY--VSM 148
Query: 412 GNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVP 549
G AEN A + +I+R+DQD +A S +++ A K + E+VP P
Sbjct: 149 GITAENVANRYKISREDQDAFAYQSQMKASKAKAEKQYT-EIVPTP 193
>UniRef50_Q9KWK4 Cluster: Putative acetyl-CoA C-acetyltransferase
vraB; n=17; Staphylococcus|Rep: Putative acetyl-CoA
C-acetyltransferase vraB - Staphylococcus aureus
Length = 379
Score = 72.5 bits (170), Expect = 7e-12
Identities = 49/155 (31%), Positives = 80/155 (51%)
Frame = +1
Query: 88 IKXVYIGNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQ 267
I V +GNV N G A +A++ AGL S T+++ C SG++S+ A + +Q GA
Sbjct: 48 IDDVVLGNVVG-NGGNI-ARKALLEAGLKDSIPGVTIDRQCGSGLESVQYACRMIQAGAG 105
Query: 268 DIILAGGMESMSNVPFYLKRGETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQ 447
+ +AGG+ES S P+ +KR + Y L + + M AEN AK
Sbjct: 106 KVYIAGGVESTSRAPWKIKRPHSVY-ETALPEFYERASFAPEMSDPSMIQGAENVAKMYD 164
Query: 448 ITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPV 552
++R+ QDE+A S++ +A + E++P+ V
Sbjct: 165 VSRELQDEFAYRSHQLTAENVKNGNISQEILPITV 199
>UniRef50_Q2RNW4 Cluster: Acetyl-CoA C-acetyltransferase precursor;
n=1; Rhodospirillum rubrum ATCC 11170|Rep: Acetyl-CoA
C-acetyltransferase precursor - Rhodospirillum rubrum
(strain ATCC 11170 / NCIB 8255)
Length = 386
Score = 71.7 bits (168), Expect = 1e-11
Identities = 53/156 (33%), Positives = 77/156 (49%)
Frame = +1
Query: 88 IKXVYIGNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQ 267
I V +GNV G A + AGLP + +V++ C SG+++I+ AA ++ GA
Sbjct: 48 IDEVILGNVLQ---GGNVARSCALEAGLPPAVPALSVDRQCGSGLEAILQAAWKIRAGAA 104
Query: 268 DIILAGGMESMSNVPFYLKRGETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQ 447
+ILAGG+ES S P+ ++R + + V F G + M A+ A+
Sbjct: 105 RVILAGGVESTSCAPWRVERPSSPTDLPRFVAQAPFSG--GGHRDPSMIEGADAVAETCG 162
Query: 448 ITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPVP 555
I R QD YA S+ R+ AA A F ELV V P
Sbjct: 163 IGRAAQDAYAAGSHARALAAQAAGRFAGELVSVYGP 198
>UniRef50_A5DXV8 Cluster: 3-ketoacyl-CoA thiolase B; n=5;
Dikarya|Rep: 3-ketoacyl-CoA thiolase B - Lodderomyces
elongisporus (Yeast) (Saccharomyces elongisporus)
Length = 411
Score = 71.7 bits (168), Expect = 1e-11
Identities = 47/170 (27%), Positives = 81/170 (47%), Gaps = 2/170 (1%)
Frame = +1
Query: 58 IEXAGIPKXXIKXVYIGNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIML 237
I+ + ++ + IGNV A G A++ AG P ++ +N++C+SG+ +I
Sbjct: 50 IKKTNLDPKLVQDIAIGNVLHARGGDFEHRAALMSAGFPHTSPFIAINRLCSSGLMAISQ 109
Query: 238 AAQGLQTGAQDIILAGGMESMSNVPFYLKRGETSYGGMQLV--DGIVFDGLTDVYNKFHM 411
A ++ G + + GG+ESM+ YG LV D + + M
Sbjct: 110 VANKIRVGEIECGIGGGVESMTK----------DYGPQALVQIDPAYAENEEFKKTQIPM 159
Query: 412 GNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPVPQK 561
G EN +K I R QD++A +SY ++ A + F DE++P+ V Q+
Sbjct: 160 GITNENVCEKFNIKRDVQDQFAASSYNKAEKAQKEGRFKDEILPIEVYQE 209
>UniRef50_A1D2F8 Cluster: 3-ketoacyl-CoA ketothiolase (Kat1),
putative; n=27; Eukaryota|Rep: 3-ketoacyl-CoA
ketothiolase (Kat1), putative - Neosartorya fischeri
(strain ATCC 1020 / DSM 3700 / NRRL 181)(Aspergillus
fischerianus (strain ATCC 1020 / DSM 3700 / NRRL 181))
Length = 435
Score = 71.7 bits (168), Expect = 1e-11
Identities = 52/167 (31%), Positives = 80/167 (47%), Gaps = 4/167 (2%)
Frame = +1
Query: 73 IPKXXIKXVYIGNVCSANLGQAPAXQ----AVIFAGLPKSTICTTVNKVCASGMKSIMLA 240
+ K + I +VC N+ A A + AG+P + ++VN+ C+SG+K++
Sbjct: 84 VQKSKLDPALIEDVCLGNVNDGKAAYLVRAAALAAGIPHTAGASSVNRFCSSGLKAVQDI 143
Query: 241 AQGLQTGAQDIILAGGMESMSNVPFYLKRGETSYGGMQLVDGIVFDGLTDVYNKFHMGNC 420
A +Q GA D+ +A G E MS L R + L + D + MG
Sbjct: 144 ANQIQLGAIDVGVAVGAELMSAGGDRLPR---PFNEEVLKNQEAADCMQP------MGQT 194
Query: 421 AENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPVPQK 561
+EN ITR+ QD YA S++R+ AA +A F DE+VP+ K
Sbjct: 195 SENVGADFNITREMQDTYAAESFRRAEAAQKAGWFDDEIVPITTKVK 241
>UniRef50_Q08VP3 Cluster: 3-ketoacyl-CoA thiolase; n=1; Stigmatella
aurantiaca DW4/3-1|Rep: 3-ketoacyl-CoA thiolase -
Stigmatella aurantiaca DW4/3-1
Length = 378
Score = 71.3 bits (167), Expect = 2e-11
Identities = 52/186 (27%), Positives = 85/186 (45%), Gaps = 18/186 (9%)
Frame = +1
Query: 58 IEXAGIPKXXIKXVYIGNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIML 237
++ A I I V G V + A + VI AGLP+ TV + CA+ ++S+
Sbjct: 45 VQRADIDPNEINQVVFGQVIPTLTAPSIAREVVIAAGLPRKIEAFTVARACATSIQSMTT 104
Query: 238 AAQGLQTGAQDIILAGGMESMSNVPFYLKRG-----ETSYGGMQLVDGI----------- 369
AA + G ++I+AGG ESMS+ P + R S L + +
Sbjct: 105 AANAIAVGEAEVIIAGGTESMSDAPIFTSRPLAHALVASSKAKSLPEKLKPFQKLQGKDL 164
Query: 370 --VFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVP 543
V + + MG AE AK+ I+R++QD A S++ +A A++ F E++
Sbjct: 165 LPVPPAIAEYSTGMTMGESAEKMAKENGISREEQDRIAYASHQNAARAWQEGRFDSEVMH 224
Query: 544 VPVPQK 561
V +P +
Sbjct: 225 VVIPPR 230
>UniRef50_Q2PQZ1 Cluster: Beta-ketothiolase; n=1; Rhodococcus sp.
T104|Rep: Beta-ketothiolase - Rhodococcus sp. T104
Length = 397
Score = 70.9 bits (166), Expect = 2e-11
Identities = 47/167 (28%), Positives = 83/167 (49%), Gaps = 4/167 (2%)
Frame = +1
Query: 58 IEXAGIPKXXIKXVYIGNVCSANLGQAP---AXQAVIFAGLPKSTICTTVNKVCASGMKS 228
I +G+ ++ + IG C+A G+ A + G P +++ C S +
Sbjct: 52 IRRSGLDPAVVEDLVIG--CTAPFGEQSRNIGRNAWLQVGYPPEVPAVVLDRRCGSAQTA 109
Query: 229 IMLAAQGLQTGAQDIILAGGMESMSNVPFYLKRGETSYGGMQLVDGIVF-DGLTDVYNKF 405
+ + A + +G D++LAGG+E M +VP TS + + G + + L + Y+
Sbjct: 110 VEMGAALVGSGTHDVVLAGGVEHMGHVPI------TSPAKISELYGDPWPEALRERYDFV 163
Query: 406 HMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPV 546
H G AE A + I+RQ+ DE+AV S++ + A EA F E++P+
Sbjct: 164 HQGESAELIADRWGISRQEMDEFAVRSHRLATEAIEAGRFDTEMIPL 210
>UniRef50_Q05493 Cluster: 3-ketoacyl-CoA thiolase, peroxisomal
precursor; n=17; Ascomycota|Rep: 3-ketoacyl-CoA
thiolase, peroxisomal precursor - Yarrowia lipolytica
(Candida lipolytica)
Length = 414
Score = 70.9 bits (166), Expect = 2e-11
Identities = 48/164 (29%), Positives = 79/164 (48%), Gaps = 1/164 (0%)
Frame = +1
Query: 58 IEXAGIPKXXIKXVYIGNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIML 237
++ + I I V GNV +A G A + AG+P++ +N+ C+SG+ ++
Sbjct: 65 VKESKIDPKLIGDVVCGNVLAAGAGATEHRAACLVAGIPETVPFVALNRQCSSGLMAVND 124
Query: 238 AAQGLQTGAQDIILAGGMESMSNVPFYLKRGETSYGGMQLVDGIVFDGLTDVYN-KFHMG 414
A ++ G DI + G+ESMSN Y T + F + MG
Sbjct: 125 VANKIRAGQIDIGIGCGVESMSNQ--YGPNSVTPFSNK-------FQNNEEAKKCLIPMG 175
Query: 415 NCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPV 546
+EN A K ++R+ QD +A SY+++AAA A F E++P+
Sbjct: 176 ITSENVAAKYNVSRKAQDAFAAKSYEKAAAAQAAGKFDQEILPI 219
>UniRef50_A6DTH4 Cluster: Acetyl-CoA acetyltransferase; n=1;
Lentisphaera araneosa HTCC2155|Rep: Acetyl-CoA
acetyltransferase - Lentisphaera araneosa HTCC2155
Length = 393
Score = 70.5 bits (165), Expect = 3e-11
Identities = 47/154 (30%), Positives = 78/154 (50%), Gaps = 1/154 (0%)
Frame = +1
Query: 88 IKXVYIGNVC-SANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGA 264
I+ + +G+ A G A Q AGL T+N+ CASG++SI +A Q + G
Sbjct: 50 IEDLMLGSATPEAEQGMNMAMQVGQAAGLGNKITGVTINRFCASGLQSIAMAHQAIACGH 109
Query: 265 QDIILAGGMESMSNVPFYLKRGETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKL 444
++ AGG ESMS + T G + + + D D Y +MGN AE AK+
Sbjct: 110 ASVLAAGGCESMSLL--------TLGGNNFVANPKLNDIFPDAY--LNMGNTAEAVAKQY 159
Query: 445 QITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPV 546
++R D++++ S++ + A E F +E++P+
Sbjct: 160 NVSRTSMDKFSLRSHENALKAIEQGYFKEEIIPL 193
>UniRef50_A0NXK3 Cluster: Acetyl-CoA C-acetyltransferase; n=2;
Alphaproteobacteria|Rep: Acetyl-CoA C-acetyltransferase
- Stappia aggregata IAM 12614
Length = 395
Score = 69.7 bits (163), Expect = 5e-11
Identities = 47/169 (27%), Positives = 76/169 (44%)
Frame = +1
Query: 1 GRFSXFXXXXXXXXXXXXXIEXAGIPKXXIKXVYIGNVCSANLGQAPAXQAVIFAGLPKS 180
G + F I AGI + V++GN G PA A + AGL ++
Sbjct: 22 GALAKFQADELAAPVLAQLIVDAGIEPGDVDFVFLGNALYG--GGNPARLAALRAGLSQT 79
Query: 181 TICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPFYLKRGETSYGGMQLV 360
T++ C SG+ +I++ A+ ++ GA +I+LAGG ES S P + R
Sbjct: 80 VPALTIDTQCCSGLDAILMGARMIEAGAAEIVLAGGTESFSRSPIRMTRPADRAEPSVAY 139
Query: 361 DGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAA 507
D F D ++ + A A + T++ Q YAV S+ ++A+A
Sbjct: 140 DRPAF--APDSFDDPDLAEAAAKLAAETGTTKEAQAAYAVASHHKAASA 186
>UniRef50_P09110 Cluster: 3-ketoacyl-CoA thiolase, peroxisomal
precursor; n=50; cellular organisms|Rep: 3-ketoacyl-CoA
thiolase, peroxisomal precursor - Homo sapiens (Human)
Length = 424
Score = 69.3 bits (162), Expect = 6e-11
Identities = 46/150 (30%), Positives = 79/150 (52%)
Frame = +1
Query: 97 VYIGNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDII 276
+ +GNV G A A + +P++ +TVN+ C+SG++++ A G++ G+ DI
Sbjct: 86 ICVGNVLQPGAGAIMARIAQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIG 145
Query: 277 LAGGMESMSNVPFYLKRGETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITR 456
+A G+ESMS RG +L++ + D MG +EN A++ I+R
Sbjct: 146 MACGVESMS----LADRGNPGNITSRLMEK---EKARDCL--IPMGITSENVAERFGISR 196
Query: 457 QDQDEYAVNSYKRSAAAYEAKAFVDELVPV 546
+ QD +A+ S +++A A F E+VPV
Sbjct: 197 EKQDTFALASQQKAARAQSKGCFQAEIVPV 226
>UniRef50_A0JVH9 Cluster: Acetyl-CoA acetyltransferases; n=20;
Bacteria|Rep: Acetyl-CoA acetyltransferases -
Arthrobacter sp. (strain FB24)
Length = 443
Score = 68.9 bits (161), Expect = 8e-11
Identities = 45/133 (33%), Positives = 67/133 (50%), Gaps = 1/133 (0%)
Frame = +1
Query: 151 AVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPFYLKRG 330
A + AGLP++ V+++CA M ++ A G+ GA D+++AGG+E M N P G
Sbjct: 94 AALLAGLPRTVPGFAVDRMCAGAMTAVTTTASGIAFGAYDVVIAGGVEHMGNHPM----G 149
Query: 331 ETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKL-QITRQDQDEYAVNSYKRSAAA 507
E + + + + D +MGN AEN + IT+ D YAV S + AAA
Sbjct: 150 EGADPNPRFMSERLVDPAA-----LNMGNTAENLHDRFPAITKDRTDAYAVASQDKLAAA 204
Query: 508 YEAKAFVDELVPV 546
Y +LVPV
Sbjct: 205 YGKGQIQPDLVPV 217
>UniRef50_Q4DNU4 Cluster: Putative uncharacterized protein; n=1;
Trypanosoma cruzi|Rep: Putative uncharacterized protein
- Trypanosoma cruzi
Length = 396
Score = 68.9 bits (161), Expect = 8e-11
Identities = 50/140 (35%), Positives = 76/140 (54%), Gaps = 6/140 (4%)
Frame = +1
Query: 166 GLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPFYLKRGETS-- 339
G P ++ T +++ CASG +I A+ + G + +AGG+ESMSN P YL T
Sbjct: 74 GAPITSGGTMLHENCASGGAAIHDVARRILLGEISVGMAGGVESMSNTPRYLYTCRTKNK 133
Query: 340 -YGGMQLVDGIVFDGLTD--VYNKFH-MGNCAENTAKKLQITRQDQDEYAVNSYKRSAAA 507
YG + LVDG++ + LTD V N MG E +K ++R+ QDE A S+ + A
Sbjct: 134 LYGDLTLVDGLM-EALTDCNVGNGGELMGLLTERLVEKYGVSRELQDEIAFRSHANATAT 192
Query: 508 YEAKAFVDELVPVPVPQKRG 567
++ K D + PV V ++G
Sbjct: 193 WK-KGMFDYVTPVDVFDRKG 211
>UniRef50_Q0FF19 Cluster: Putative acetyl-CoA c-acetyltransferase;
n=1; alpha proteobacterium HTCC2255|Rep: Putative
acetyl-CoA c-acetyltransferase - alpha proteobacterium
HTCC2255
Length = 369
Score = 68.5 bits (160), Expect = 1e-10
Identities = 43/148 (29%), Positives = 75/148 (50%)
Frame = +1
Query: 58 IEXAGIPKXXIKXVYIGNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIML 237
++ A +P I + + N G PA + AGLP+ T+++ C G+ +I L
Sbjct: 39 LKEANVPSTSINEIILSNAVGG--GGNPARPTALAAGLPEHIGGFTIDRQCTGGLDAIWL 96
Query: 238 AAQGLQTGAQDIILAGGMESMSNVPFYLKRGETSYGGMQLVDGIVFDGLTDVYNKFHMGN 417
AAQ + +G+ +II+AGG ES S P ++ + G D +F GL D M +
Sbjct: 97 AAQMVMSGSHNIIIAGGSESASCRPIRMRINHNT-GEKIAYDRPIFTGLKD--RDPDMID 153
Query: 418 CAENTAKKLQITRQDQDEYAVNSYKRSA 501
A I+++ Q+ +A+NS+K+++
Sbjct: 154 SVAEIAVSSGISKEAQEAWAINSHKKAS 181
>UniRef50_A0LKL0 Cluster: Acetyl-CoA acetyltransferases; n=1;
Syntrophobacter fumaroxidans MPOB|Rep: Acetyl-CoA
acetyltransferases - Syntrophobacter fumaroxidans
(strain DSM 10017 / MPOB)
Length = 426
Score = 68.5 bits (160), Expect = 1e-10
Identities = 53/197 (26%), Positives = 92/197 (46%), Gaps = 27/197 (13%)
Frame = +1
Query: 58 IEXAGIPKXXIKXVYIGNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIML 237
++ A + ++ V +G + A A++ AG P T+++ C SG+ +I
Sbjct: 38 VKRANVDPARVEDVIMGQSYQSGEYVNIARMALLTAGWPVEVPGITLDRRCCSGLDAICF 97
Query: 238 AAQGLQTGAQDIILAGGMESMSNVPFYLK----------------------RGETSYGGM 351
A +Q G I++AGG+ESMS FY+ G S G+
Sbjct: 98 GAMKIQCGHASIVVAGGVESMSTAEFYIPGEFIKWGMEGRRDPRWGFMPRGHGSLSMWGL 157
Query: 352 QLVDGI----VFDGLTDVYNKFH-MGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEA 516
L D I V + + + + M AE A+ I+R++ D +A+ S++R+ A ++
Sbjct: 158 PLFDRIQRARVMSQPIERFGELNSMMTWAEAAARGENISREEADRWALRSHRRACEAIDS 217
Query: 517 KAFVDELVPVPVPQKRG 567
F +E+VPV VP+K+G
Sbjct: 218 GKFREEIVPVVVPRKKG 234
>UniRef50_A1W8A4 Cluster: Acetyl-CoA acetyltransferases; n=3;
Comamonadaceae|Rep: Acetyl-CoA acetyltransferases -
Acidovorax sp. (strain JS42)
Length = 389
Score = 68.1 bits (159), Expect = 1e-10
Identities = 50/160 (31%), Positives = 75/160 (46%)
Frame = +1
Query: 67 AGIPKXXIKXVYIGNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQ 246
AG+P + V +GN A G PA + AGLP+ T++ C +G+ ++ A
Sbjct: 41 AGLPAEAVDAVVLGNALGA--GGNPARMLALAAGLPEGIPAVTLDSQCCAGLDAVTHACG 98
Query: 247 GLQTGAQDIILAGGMESMSNVPFYLKRGETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAE 426
L G D+++AGG E+ S P + R + D F M A
Sbjct: 99 LLALGQADVVVAGGAEAWSRAPLRMHRPLQAEEAPVPYDRPPFTPWP--ARDPDMLLAAL 156
Query: 427 NTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPV 546
+ A++L +TR QD YA+ S+ RS AA A A E+VP+
Sbjct: 157 DGARRLGLTRHAQDAYAMASHARSVAARAAMA--HEIVPL 194
>UniRef50_A1I8F4 Cluster: Acetyl-CoA C-acyltransferase; n=1;
Candidatus Desulfococcus oleovorans Hxd3|Rep: Acetyl-CoA
C-acyltransferase - Candidatus Desulfococcus oleovorans
Hxd3
Length = 391
Score = 68.1 bits (159), Expect = 1e-10
Identities = 44/129 (34%), Positives = 64/129 (49%), Gaps = 2/129 (1%)
Frame = +1
Query: 166 GLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPFYLKRG--ETS 339
G P+S T+ C SGM + M AA+ + TG DI++A G E M VP
Sbjct: 78 GYPESVPSNTITNQCPSGMAATMHAARAIITGEADIMIAAGAEDMEKVPMAANMDFPPRL 137
Query: 340 YGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAK 519
+ L D F MG+ AE A+ +I+R+D D A+ S K++AAA +A
Sbjct: 138 FSRYNLAD-------------FPMGSTAEKVAEMYKISREDMDNMAIWSNKKAAAARDAG 184
Query: 520 AFVDELVPV 546
F +E+VP+
Sbjct: 185 KFKNEIVPI 193
>UniRef50_Q02X83 Cluster: Acetyl-CoA acetyltransferase; n=2;
Lactococcus lactis|Rep: Acetyl-CoA acetyltransferase -
Lactococcus lactis subsp. cremoris (strain SK11)
Length = 382
Score = 67.3 bits (157), Expect = 3e-10
Identities = 45/157 (28%), Positives = 76/157 (48%)
Frame = +1
Query: 73 IPKXXIKXVYIGNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGL 252
+ K I V +GNV N G A + + AG T++ C SG+ +++ AA +
Sbjct: 47 LKKSEIDYVILGNV--TNQGGNLARRCALKAGFSTEVPAFTIDHQCGSGLTALITAANYI 104
Query: 253 QTGAQDIILAGGMESMSNVPFYLKRGETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENT 432
Q+G II GG+E+ S + + + F + Y MG A+ T
Sbjct: 105 QSGGASIICTGGVENTS-------QSNITIDAKSQLPIKRFKMAPEPYEDLDMGIIADIT 157
Query: 433 AKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVP 543
A K I+R+ QD YA+NS++++ A + K+ + E++P
Sbjct: 158 ALKYNISRESQDLYALNSHQKANQAIKNKSLMSEVLP 194
>UniRef50_Q63YX8 Cluster: Beta-ketoadipyl CoA thiolase; n=96;
cellular organisms|Rep: Beta-ketoadipyl CoA thiolase -
Burkholderia pseudomallei (Pseudomonas pseudomallei)
Length = 401
Score = 66.9 bits (156), Expect = 3e-10
Identities = 44/132 (33%), Positives = 69/132 (52%)
Frame = +1
Query: 151 AVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPFYLKRG 330
AV+ AG ++T +N+ CASG+++ +AA + +G ++ + GG+ESMS VP
Sbjct: 71 AVLAAGYAETTAGVQINRFCASGLEACNMAAAQVMSGQSEMAIGGGVESMSRVPM----- 125
Query: 331 ETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAY 510
S GG VD + + + G A+ A K +R D D YA S++R+ AA
Sbjct: 126 -GSSGGAWPVDPAI--AIPSYF--VPQGVSADTIATKWGYSRADVDAYAAESHRRAHAAA 180
Query: 511 EAKAFVDELVPV 546
+A F +VPV
Sbjct: 181 QAGWFARSIVPV 192
>UniRef50_Q89H19 Cluster: Acyl-CoA thiolase; n=4;
Proteobacteria|Rep: Acyl-CoA thiolase - Bradyrhizobium
japonicum
Length = 410
Score = 66.5 bits (155), Expect = 4e-10
Identities = 45/128 (35%), Positives = 65/128 (50%)
Frame = +1
Query: 163 AGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPFYLKRGETSY 342
AG T+++ C SG+ S+ +AA + GA+D+++AGG E MS +RG
Sbjct: 77 AGYDVRASAVTLDRFCGSGITSVNMAASSIMAGAEDLVIAGGCEMMS---MEGRRG---- 129
Query: 343 GGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKA 522
GG ++DG L + + H G CA+ A ITR+D D + S KR+A A
Sbjct: 130 GGPMMMDGGNL-RLRARHPQSHQGVCADAIATMEGITRRDVDALGLESQKRAAHAIANGH 188
Query: 523 FVDELVPV 546
F LVPV
Sbjct: 189 FKKSLVPV 196
>UniRef50_Q2IN02 Cluster: Acetyl-CoA C-acyltransferase; n=3;
Myxococcales|Rep: Acetyl-CoA C-acyltransferase -
Anaeromyxobacter dehalogenans (strain 2CP-C)
Length = 435
Score = 64.5 bits (150), Expect = 2e-09
Identities = 49/183 (26%), Positives = 82/183 (44%), Gaps = 18/183 (9%)
Frame = +1
Query: 67 AGIPKXXIKXVYIGNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQ 246
+G+P V G V + + V+ LP+S TV + CA+ +++ A
Sbjct: 50 SGLPPNAFDSVVFGQVIPSPTVTLIGREMVLRTQLPRSVQAHTVARACATSIQAATDVAD 109
Query: 247 GLQTGAQDIILAGGMESMSNVPFY-----------LKRGETSYGGMQLVDGI-------V 372
++ G D +AGG ES+S+ P + L R T +++ G+
Sbjct: 110 QIRLGHSDCAIAGGAESVSDAPIFASRPLAQALVELSRARTLADRARILAGLRPRDFTPT 169
Query: 373 FDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPV 552
L + MG AE A+ I+R QD A S++R+A A++A F +E++ VPV
Sbjct: 170 PPALKEPTTGLTMGESAEKMAQVNGISRAAQDRLAYESHRRAAEAWDAGRFDEEVMHVPV 229
Query: 553 PQK 561
P +
Sbjct: 230 PPR 232
>UniRef50_Q47DJ3 Cluster: Thiolase; n=2; Bacteria|Rep: Thiolase -
Dechloromonas aromatica (strain RCB)
Length = 395
Score = 63.3 bits (147), Expect = 4e-09
Identities = 44/151 (29%), Positives = 73/151 (48%), Gaps = 1/151 (0%)
Frame = +1
Query: 58 IEXAGIPKXXIKXVYIGNVCSAN-LGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIM 234
++ +G+ + V G V A G A QA++ AGLP ++N++C S ++
Sbjct: 41 VKRSGVSVSGVADVIAGCVSQAGEQGANIARQALLLAGLPAEIPGVSLNRMCGSSQYAVH 100
Query: 235 LAAQGLQTGAQDIILAGGMESMSNVPFYLKRGETSYGGMQLVDGIVFDGLTDVYNKFHMG 414
AAQ + G + + G+E+MS VP +L G + D + G+T + H
Sbjct: 101 AAAQSILAGDAEFSVGCGVENMSRVPMFLDL-TLGKGDFKGFDNL-HPGITARFAIPHQV 158
Query: 415 NCAENTAKKLQITRQDQDEYAVNSYKRSAAA 507
AE QI+R + DE+A S++R+ AA
Sbjct: 159 ESAELIGDHWQISRAECDEFARESHRRAHAA 189
>UniRef50_Q6ACV5 Cluster: Acetyl-coA acyltransferase; n=2;
Actinomycetales|Rep: Acetyl-coA acyltransferase -
Leifsonia xyli subsp. xyli
Length = 371
Score = 62.9 bits (146), Expect = 5e-09
Identities = 51/162 (31%), Positives = 71/162 (43%)
Frame = +1
Query: 61 EXAGIPKXXIKXVYIGNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIMLA 240
E A + V +GN G PA A + AG + TV++ C SG+ +++ A
Sbjct: 42 EAAANASLPLADVLLGNCMGP--GGNPARVAALAAGFGAAVPGGTVDRQCGSGLAAVLDA 99
Query: 241 AQGLQTGAQDIILAGGMESMSNVPFYLKRGETSYGGMQLVDGIVFDGLTDVYNKFHMGNC 420
++ G + LAGG ES S P G Y G D M
Sbjct: 100 VSAIRAGDGRVRLAGGAESASTAPVRAS-GGVPYDRAPFAPA----GFPDP----DMPRA 150
Query: 421 AENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPV 546
AE+ A+ I+R+ QD YA S+ R+ AA EA F ELVP+
Sbjct: 151 AEDLAQADGISRERQDAYAARSHARARAAREAGRFAGELVPL 192
>UniRef50_Q18QM7 Cluster: Acetyl-CoA acetyltransferases; n=2;
Desulfitobacterium hafniense|Rep: Acetyl-CoA
acetyltransferases - Desulfitobacterium hafniense
(strain DCB-2)
Length = 435
Score = 62.5 bits (145), Expect = 7e-09
Identities = 37/142 (26%), Positives = 72/142 (50%), Gaps = 2/142 (1%)
Frame = +1
Query: 142 AXQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPFYL 321
A Q ++ AG+ T T ++ C S + ++ A+ ++ G +++ GG S S VPF L
Sbjct: 76 ARQTMLKAGISPETPSITYDQACTSALSTVKYGARSIKLGEAQMVMTGGSTSFSTVPFLL 135
Query: 322 KRGETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAE--NTAKKLQITRQDQDEYAVNSYKR 495
+ + + G + +V D + + K + + N A + ++RQ+QDE A+ S+ +
Sbjct: 136 R--DIRWEGKKHSSFLVEDPIIPLGYKDYAPVAVDSGNVAVEYGVSRQEQDELALASHVK 193
Query: 496 SAAAYEAKAFVDELVPVPVPQK 561
A+E F E+ P+ + +K
Sbjct: 194 YGQAWERGFFKGEMEPLEITKK 215
>UniRef50_Q4Q698 Cluster: Thiolase protein-like protein; n=7;
Trypanosomatidae|Rep: Thiolase protein-like protein -
Leishmania major
Length = 440
Score = 62.5 bits (145), Expect = 7e-09
Identities = 53/175 (30%), Positives = 80/175 (45%), Gaps = 17/175 (9%)
Frame = +1
Query: 88 IKXVYIGNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQ 267
I + GNV A + VI +PK I + CASG+ S+ A ++ G
Sbjct: 56 IDHIVWGNVVLQGSAHNCAREIVIDLNMPKKIIGNLTSMACASGLSSLSQACMLIEGGHA 115
Query: 268 DIILAGGMESMSNVPFYLKRGETSYGGMQLVDGIVFDGLTDV-YN--KFHMGNCA---EN 429
D+++AGG +S+SN L R T YG M V + YN K+ G A +
Sbjct: 116 DVVIAGGSDSVSNTEVPLPRAVT-YGLMMAQRKGVMSFFKEAGYNPLKWFPGGIALTERS 174
Query: 430 TAKKL-----------QITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPVPQK 561
T K + I+R+DQ+ A S+ +A A +A F +E+VPV + +K
Sbjct: 175 TGKTMGWHGDLIAELNSISREDQEALAAASHANAARAEKAGYFKEEIVPVTIDKK 229
>UniRef50_UPI00006D84CA Cluster: COG0183: Acetyl-CoA
acetyltransferase; n=1; Pseudomonas aeruginosa
C3719|Rep: COG0183: Acetyl-CoA acetyltransferase -
Pseudomonas aeruginosa C3719
Length = 131
Score = 62.1 bits (144), Expect = 1e-08
Identities = 33/89 (37%), Positives = 46/89 (51%)
Frame = +1
Query: 1 GRFSXFXXXXXXXXXXXXXIEXAGIPKXXIKXVYIGNVCSANLGQAPAXQAVIFAGLPKS 180
G F +E A + + +G V +A GQAPA QAV+ AGL +
Sbjct: 22 GDFKDVNAATLGAAAVRAEVERALLQADEVDEDALGCVLAAGQGQAPARQAVLGAGLARG 81
Query: 181 TICTTVNKVCASGMKSIMLAAQGLQTGAQ 267
T C+T+NK+C SGMK++MLA L A+
Sbjct: 82 TPCSTLNKMCGSGMKALMLAHDTLLAAAR 110
>UniRef50_A4F8Z3 Cluster: Acetyl-CoA acetyltransferase; n=2;
Actinomycetales|Rep: Acetyl-CoA acetyltransferase -
Saccharopolyspora erythraea (strain NRRL 23338)
Length = 479
Score = 62.1 bits (144), Expect = 1e-08
Identities = 50/150 (33%), Positives = 69/150 (46%)
Frame = +1
Query: 97 VYIGNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDII 276
V +GNV G A A + AGL TV++ CASG+ +I AA ++ GA D
Sbjct: 156 VVLGNVLGP--GGNTARVASLLAGLGHDVPGMTVDRQCASGLSAITTAAALIRAGAGDWY 213
Query: 277 LAGGMESMSNVPFYLKRGETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITR 456
LAGG ES S P+ R ++ + F MG A+ A + I+R
Sbjct: 214 LAGGAESPSTAPWRAWRPRSAAEPPRFYARAPF--APPEIGDPEMGPAADLVAAEAGISR 271
Query: 457 QDQDEYAVNSYKRSAAAYEAKAFVDELVPV 546
Q QD +A S+ R+ AA F E+V V
Sbjct: 272 QRQDAFAARSHARAVAAQAEGRFDAEVVDV 301
>UniRef50_Q96CA6 Cluster: ACAA1 protein; n=16; Tetrapoda|Rep: ACAA1
protein - Homo sapiens (Human)
Length = 331
Score = 45.6 bits (103), Expect(2) = 1e-08
Identities = 21/67 (31%), Positives = 39/67 (58%)
Frame = +1
Query: 97 VYIGNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDII 276
+ +GNV G A A + +P++ +TVN+ C+SG++++ A G++ G+ DI
Sbjct: 86 ICVGNVLQPGAGAIMARIAQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIG 145
Query: 277 LAGGMES 297
+A G+ S
Sbjct: 146 MACGITS 152
Score = 36.3 bits (80), Expect(2) = 1e-08
Identities = 17/45 (37%), Positives = 28/45 (62%)
Frame = +1
Query: 412 GNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPV 546
G +EN A++ I+R+ QD +A+ S +++A A F E+VPV
Sbjct: 149 GITSENVAERFGISREKQDTFALASQQKAARAQSKGCFQAEIVPV 193
>UniRef50_Q8NCW8 Cluster: 3-oxoacyl-CoA thiolase; n=21;
Fungi/Metazoa group|Rep: 3-oxoacyl-CoA thiolase - Homo
sapiens (Human)
Length = 326
Score = 61.7 bits (143), Expect = 1e-08
Identities = 41/132 (31%), Positives = 72/132 (54%)
Frame = +1
Query: 151 AVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPFYLKRG 330
A + +P++ +TVN+ C+SG++++ A G++ G+ DI +A G+ESMS RG
Sbjct: 6 AQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVESMS----LADRG 61
Query: 331 ETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAY 510
+L++ + D MG +EN A++ I+R+ QD +A+ S +++A A
Sbjct: 62 NPGNITSRLMEK---EKARDCL--IPMGITSENVAERFGISREKQDTFALASQQKAARAQ 116
Query: 511 EAKAFVDELVPV 546
F E+VPV
Sbjct: 117 SKGCFQAEIVPV 128
>UniRef50_Q5UWD8 Cluster: Acetyl-coA acetyltransferase; n=6;
Halobacteriaceae|Rep: Acetyl-coA acetyltransferase -
Haloarcula marismortui (Halobacterium marismortui)
Length = 381
Score = 60.9 bits (141), Expect = 2e-08
Identities = 40/139 (28%), Positives = 73/139 (52%)
Frame = +1
Query: 130 GQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNV 309
G+ A Q+++ G P++ T ++C S + +++ AA+ ++ G + G+E MS V
Sbjct: 67 GRNLARQSILAGGFPETVPGATTTRLCGSSLTTLVDAARAIEAGDGAVYPVAGVEHMSTV 126
Query: 310 PFYLKRGETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSY 489
PF + + ++ +D ++ MG AE A+ I+R+ QDE+A+ S+
Sbjct: 127 PF----SDWLHPAIEQR----YDP-----DRLPMGQTAETIARTHDISRKAQDEFALRSH 173
Query: 490 KRSAAAYEAKAFVDELVPV 546
+R+ AA E+ F E VPV
Sbjct: 174 ERAVAAMESGRFDAETVPV 192
>UniRef50_Q5YQT4 Cluster: Putative acyl-CoA thiolase; n=1; Nocardia
farcinica|Rep: Putative acyl-CoA thiolase - Nocardia
farcinica
Length = 430
Score = 60.1 bits (139), Expect = 4e-08
Identities = 50/186 (26%), Positives = 81/186 (43%), Gaps = 20/186 (10%)
Frame = +1
Query: 58 IEXAGIPKXXIKXVYIGNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIML 237
+E +P ++ + G V + A + + L TV + CASG++++
Sbjct: 43 LERTALPGDQVQAIVWGGVILPSAAPNIAREIALDLKLDPGCEGHTVTRACASGLQAVTT 102
Query: 238 AAQGLQTGAQDIILAGGMESMSNVPFYLKR------GETSYGGMQLVD----GIVFDGLT 387
AA ++ G D+++AGG +S SN L + + G +L D T
Sbjct: 103 AAAAIERGEYDVMIAGGSDSTSNAEIKLPQKLVHAGAPIALGKPKLKDYLSAAAQLAPFT 162
Query: 388 DVYNKFH----------MGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDEL 537
D+ MG AE A+ I R +QDE+A S+ R+AAA E+ F DE+
Sbjct: 163 DILPSRPRIAERTTGEVMGESAEKMARIHGIGRAEQDEFAARSHHRAAAAIESGRFDDEV 222
Query: 538 VPVPVP 555
+ V P
Sbjct: 223 LRVRTP 228
>UniRef50_Q1GSM2 Cluster: Acetyl-CoA C-acyltransferase; n=20;
Proteobacteria|Rep: Acetyl-CoA C-acyltransferase -
Sphingopyxis alaskensis (Sphingomonas alaskensis)
Length = 416
Score = 60.1 bits (139), Expect = 4e-08
Identities = 42/135 (31%), Positives = 63/135 (46%)
Frame = +1
Query: 151 AVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPFYLKRG 330
A + AG TT+++ C G+ S+ LAA + +G +D ++AGG E MS L
Sbjct: 73 AALSAGYDIKASGTTLDRFCGGGITSVNLAAATVMSGMEDCVVAGGTEMMSYTA-QLAAE 131
Query: 331 ETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAY 510
E + G L G L +++ + H G C + A I R D A+ S +R+ A
Sbjct: 132 EANAGIKPLGMGAGHAALDELHPQSHQGVCGDAIAAIEGIDRAAVDALALVSQRRADRAI 191
Query: 511 EAKAFVDELVPVPVP 555
+ F LVPV P
Sbjct: 192 KEGRFAKSLVPVLNP 206
>UniRef50_Q9HZJ3 Cluster: 3-ketoacyl-CoA thiolase; n=153;
Bacteria|Rep: 3-ketoacyl-CoA thiolase - Pseudomonas
aeruginosa
Length = 391
Score = 59.7 bits (138), Expect = 5e-08
Identities = 42/147 (28%), Positives = 69/147 (46%)
Frame = +1
Query: 142 AXQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPFYL 321
A A + +P ++ TV+++C S M ++ AAQ +QTG D+ + GG+E M +V
Sbjct: 73 ARMASLMTQIPHTSAAQTVSRLCGSSMSALHTAAQAIQTGNGDVFVIGGVEHMGHV---- 128
Query: 322 KRGETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSA 501
G M VD L MG AE K I+R+ QD++ S++ +
Sbjct: 129 -------GMMHGVDPNPHLSLYAAKASGMMGLTAEMLGKMHGISREAQDKFGARSHQLAW 181
Query: 502 AAYEAKAFVDELVPVPVPQKRGAPVIF 582
A + F DE++P+ + G +F
Sbjct: 182 KATQEGKFKDEIIPMEGYDENGFLKVF 208
>UniRef50_A0JU34 Cluster: Acetyl-CoA acetyltransferases; n=37;
Actinomycetales|Rep: Acetyl-CoA acetyltransferases -
Arthrobacter sp. (strain FB24)
Length = 412
Score = 59.3 bits (137), Expect = 7e-08
Identities = 51/171 (29%), Positives = 79/171 (46%), Gaps = 22/171 (12%)
Frame = +1
Query: 97 VYIGNVCSANLGQAPAXQA---VIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQ 267
+Y+G C+ G+A + A I AGL + T+N+ CAS +++I +A ++ G
Sbjct: 58 LYLG--CAEPSGEAGSNMARVVTILAGLD-NVPGATINRFCASSLQTIRMAFHAIKAGEG 114
Query: 268 DIILAGGMESMSNVPFYLKRGETSYG-------------------GMQLVDGIVFDGLTD 390
D +A G+ES+S P + GET G D + + D
Sbjct: 115 DAFVAAGVESVSRYPNWTGAGETDAGNHNPRFDAARRRTEARAASNTPWTDPRLGGRMPD 174
Query: 391 VYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVP 543
+Y MG AEN A I+R +QDE+AV S R+ AA + F ++ P
Sbjct: 175 IY--IAMGQTAENVATTYGISRAEQDEWAVLSQNRAEAARASGFFSRDITP 223
>UniRef50_Q11I56 Cluster: Acetyl-CoA acetyltransferases; n=26;
Proteobacteria|Rep: Acetyl-CoA acetyltransferases -
Mesorhizobium sp. (strain BNC1)
Length = 462
Score = 57.6 bits (133), Expect = 2e-07
Identities = 46/151 (30%), Positives = 67/151 (44%), Gaps = 21/151 (13%)
Frame = +1
Query: 139 PAXQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPFY 318
PA A + G+ ++ TV C SGM+SI + ++ G D+ILAGG E++S+ P
Sbjct: 101 PARVAALRLGMGEAMRAFTVQINCGSGMQSIDTGFRLIEGGEADLILAGGAEALSHAPLV 160
Query: 319 LKRGETSYGGMQLVDGIVFD---------------------GLTDVYNKFHMGNCAENTA 435
L R + +D GLTD F MG AE
Sbjct: 161 LSRKAAGWFAQFATAKTAWDRAAALGAFRPDMAKPIIGLERGLTDPITDFSMGQTAEIIG 220
Query: 436 KKLQITRQDQDEYAVNSYKRSAAAYEAKAFV 528
+TRQ D YA+ S++R A A +A+ F+
Sbjct: 221 HAFGVTRQAADAYALESHRRLARA-QAEGFL 250
>UniRef50_P55084 Cluster: Trifunctional enzyme subunit beta,
mitochondrial precursor (TP-beta) [Includes:
3-ketoacyl-CoA thiolase (EC 2.3.1.16) (Acetyl-CoA
acyltransferase) (Beta-ketothiolase)]; n=49; cellular
organisms|Rep: Trifunctional enzyme subunit beta,
mitochondrial precursor (TP-beta) [Includes:
3-ketoacyl-CoA thiolase (EC 2.3.1.16) (Acetyl-CoA
acyltransferase) (Beta-ketothiolase)] - Homo sapiens
(Human)
Length = 474
Score = 57.6 bits (133), Expect = 2e-07
Identities = 46/186 (24%), Positives = 82/186 (44%), Gaps = 18/186 (9%)
Frame = +1
Query: 58 IEXAGIPKXXIKXVYIGNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIML 237
+ +PK + + G V A +A + AG T TV C S +++
Sbjct: 88 LHRTSVPKEVVDYIIFGTVIQEVKTSNVAREAALGAGFSDKTPAHTVTMACISANQAMTT 147
Query: 238 AAQGLQTGAQDIILAGGMESMSNVPFY-----------LKRGETSYGGMQLVDGIVFDGL 384
+ +G D+I+AGG+E MS+VP L + ++ + L+ F+ L
Sbjct: 148 GVGLIASGQCDVIVAGGVELMSDVPIRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFL 207
Query: 385 T---DVYNKFH----MGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVP 543
++F MG+ A+ A ++R +QDEYA+ S+ + A + + + ++VP
Sbjct: 208 APELPAVSEFSTSETMGHSADRLAAAFAVSRLEQDEYALRSHSLAKKAQD-EGLLSDVVP 266
Query: 544 VPVPQK 561
VP K
Sbjct: 267 FKVPGK 272
>UniRef50_Q8F7W4 Cluster: Acetyl-CoA acetyltransferase; n=4;
Leptospira|Rep: Acetyl-CoA acetyltransferase -
Leptospira interrogans
Length = 441
Score = 57.2 bits (132), Expect = 3e-07
Identities = 47/165 (28%), Positives = 76/165 (46%), Gaps = 18/165 (10%)
Frame = +1
Query: 106 GNVCSANLGQAPAXQAVI--FAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIIL 279
G V AP VI G+ C TV C SGM+++ AA+ + G ++ L
Sbjct: 53 GVVVGEGFSNAPNSARVIANLVGMRDEIACITVANNCVSGMEAVAEAARRIVLGEGEVFL 112
Query: 280 AGGMESMSNVPFYLK--RGETSYGGM---------QLVDGI-----VFDGLTDVYNKFHM 411
A G ES +++PF +K R G + L +G+ + DGL D + M
Sbjct: 113 AIGEESQTSMPFVVKNARLNKKAGSLDKLKKLLPDNLPEGVELRDTLEDGLGDGETSYGM 172
Query: 412 GNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPV 546
AE A+ ++R+ QD+ A S+KR+ A +A + ++P+
Sbjct: 173 QVTAEIVAQNYGLSREIQDKLAFESFKRALEASKAGKYSPYIIPM 217
>UniRef50_A6GHQ8 Cluster: Acetyl-CoA acetyltransferase; n=1;
Plesiocystis pacifica SIR-1|Rep: Acetyl-CoA
acetyltransferase - Plesiocystis pacifica SIR-1
Length = 415
Score = 57.2 bits (132), Expect = 3e-07
Identities = 48/160 (30%), Positives = 75/160 (46%), Gaps = 1/160 (0%)
Frame = +1
Query: 70 GIPKXXIKXVYIGNVCSA-NLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQ 246
G+ + + +G V + G A A ++AG P++ T+ + CASG+ +I AA
Sbjct: 46 GLDPTAVDDLVLGCVTQVGDQGANVAKIAALWAGWPEAVPGLTLTRFCASGLDAIGTAAA 105
Query: 247 GLQTGAQDIILAGGMESMSNVPFYLKRGETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAE 426
+ G +I+AGG+ESMS VP R G +D V + V HM A+
Sbjct: 106 RVIAGFDGLIVAGGVESMSRVPMLADR------GAWWMDPEVAERTRYV----HMALSAD 155
Query: 427 NTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPV 546
A R+ D +A+ S+ R+ AA+ F +VPV
Sbjct: 156 LIASLDGHGREALDAWALRSHVRARAAWAGGHFARSIVPV 195
>UniRef50_A4BBG3 Cluster: Acetyl-CoA acetyltransferase; n=1;
Reinekea sp. MED297|Rep: Acetyl-CoA acetyltransferase -
Reinekea sp. MED297
Length = 393
Score = 57.2 bits (132), Expect = 3e-07
Identities = 34/124 (27%), Positives = 61/124 (49%), Gaps = 1/124 (0%)
Frame = +1
Query: 196 VNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPFYLKRGETSYGGMQLVDGIVF 375
+++ C S + ++ A + GA + LAGG E MS VP + G+ +D
Sbjct: 91 IDQQCGSSLAALRFAMMTIACGANTVALAGGYEQMSRVPMGPALFKDGTLGVPTLDSAT- 149
Query: 376 DGLT-DVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPV 552
G T D+ +MG AE A ITR + D +A S++R+ + ++ DE++ +P+
Sbjct: 150 -GKTYDMTVALNMGLTAERLAAHAGITRDEMDRFACRSHERAYRSQQSGFLADEILAIPL 208
Query: 553 PQKR 564
++
Sbjct: 209 DHEK 212
>UniRef50_A0Z3Q6 Cluster: Acetyl-CoA acetyltransferase; n=1; marine
gamma proteobacterium HTCC2080|Rep: Acetyl-CoA
acetyltransferase - marine gamma proteobacterium
HTCC2080
Length = 415
Score = 57.2 bits (132), Expect = 3e-07
Identities = 38/140 (27%), Positives = 67/140 (47%)
Frame = +1
Query: 142 AXQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPFYL 321
A + ++AG P T+N+ C+SG+ +I +AA + G +++ +AGG+E MS VP
Sbjct: 84 AKSSALYAGWPSHVSGLTINRFCSSGLDAINIAALKVNAGQEEVAVAGGIEMMSRVPMMS 143
Query: 322 KRGETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSA 501
+ + + MG+ A+ A +R D DE A+ S +R+A
Sbjct: 144 DQAAIFKDPEVALSARI----------LLMGSGADLIASLYGASRHDVDEVALMSQQRAA 193
Query: 502 AAYEAKAFVDELVPVPVPQK 561
A ++ F ++P+ P K
Sbjct: 194 LARDS-GFFTSIIPIDNPVK 212
>UniRef50_Q1GCU4 Cluster: Acetyl-CoA C-acetyltransferase; n=2;
Rhodobacterales|Rep: Acetyl-CoA C-acetyltransferase -
Silicibacter sp. (strain TM1040)
Length = 367
Score = 56.8 bits (131), Expect = 4e-07
Identities = 47/165 (28%), Positives = 79/165 (47%), Gaps = 2/165 (1%)
Frame = +1
Query: 58 IEXAGIPKXXIKXVYIGNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIML 237
+E AG+ + + + N A G PA A + AGLP ++++ CA G+ +I+L
Sbjct: 36 LEDAGLAGDEVGELILSNALGA--GGNPARVAALAAGLPDHVAGLSIDRQCAGGLDAILL 93
Query: 238 AAQGLQTGAQDIILAGGMESMSNVPFYLKRGETSYGGM--QLVDGIVFDGLTDVYNKFHM 411
+Q G ++++AGG ES S P +R T G + F D M
Sbjct: 94 GHALVQAGHHEVVIAGGAESYSRRP---QRSRTFADGRPPEPYAQARFTPWPD--RDPDM 148
Query: 412 GNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPV 546
A + A+ ITR +QD++A S+ A+ +EA+ +E+V +
Sbjct: 149 AVAAADLARMQHITRAEQDDWAQRSH-ALASLHEARR-AEEIVSI 191
>UniRef50_Q81Y70 Cluster: Acetyl-CoA acetyltransferase; n=11;
Bacillus|Rep: Acetyl-CoA acetyltransferase - Bacillus
anthracis
Length = 363
Score = 56.4 bits (130), Expect = 5e-07
Identities = 48/149 (32%), Positives = 68/149 (45%)
Frame = +1
Query: 88 IKXVYIGNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQ 267
I V +GNV G A + + AGL T+++ C +G+++I A +Q G
Sbjct: 45 IDDVILGNVVGP--GGNVARLSALEAGLGHHIPGVTIDRQCGAGLEAIRTACHFIQGGGG 102
Query: 268 DIILAGGMESMSNVPFYLKRGETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQ 447
+AGG+ES S PF R S + +MG AE A+
Sbjct: 103 KCYIAGGVESTSTSPFQ-NRARFS---------------PETIGDPNMGVAAEYVAESYN 146
Query: 448 ITRQDQDEYAVNSYKRSAAAYEAKAFVDE 534
ITR+ QDEYA SYKR+ A AK ++ E
Sbjct: 147 ITREMQDEYACLSYKRTLQAL-AKGYIHE 174
>UniRef50_Q3INC2 Cluster: Acetyl-CoA C-acyltransferase 5; n=1;
Natronomonas pharaonis DSM 2160|Rep: Acetyl-CoA
C-acyltransferase 5 - Natronomonas pharaonis (strain DSM
2160 / ATCC 35678)
Length = 382
Score = 56.0 bits (129), Expect = 6e-07
Identities = 48/165 (29%), Positives = 74/165 (44%), Gaps = 3/165 (1%)
Frame = +1
Query: 61 EXAGIPKXXIKXVYIGNVCSAN-LGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIML 237
E G I+ V G V + G A A + AG +N++C SG +++
Sbjct: 39 ERNGFAPETIEDVIYGCVTPIDEQGLNIARLAPMVAGWGDGVPGVQLNRMCGSGQQAVNF 98
Query: 238 AAQGLQTGAQDIILAGGMESMSNVPFYLKRGETSYGGMQLVDGIV--FDGLTDVYNKFHM 411
AA + +GA D+++AGG+E M+ VP G + D FD LT
Sbjct: 99 AAGQVASGAHDVLIAGGVEHMTRVPM-------GSDGQSVTDTYFEHFDELTT------Q 145
Query: 412 GNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPV 546
G AE A+ +R+ DE A +S R A+EA + +++V V
Sbjct: 146 GEGAERIAETYDFSRRTLDELAADSQSRCGDAWEAGHYDEQVVSV 190
>UniRef50_Q9AG66 Cluster: Beta ketothiolase; n=5; Rhizobiaceae|Rep:
Beta ketothiolase - Rhizobium etli
Length = 235
Score = 55.2 bits (127), Expect = 1e-06
Identities = 32/101 (31%), Positives = 55/101 (54%)
Frame = +1
Query: 163 AGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPFYLKRGETSY 342
AGLP + +++ C SG+++I++AA+ +Q A LAGG+ES+S P+ ++R + +
Sbjct: 1 AGLPMAVPGVAIDRQCGSGLEAIIMAARLIQAKAGSCFLAGGVESVSTAPWRVERPKANG 60
Query: 343 GGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQ 465
+ F + MG AEN A++ I+RQ Q
Sbjct: 61 AVPRFYGRARFS--PETIGDPEMGVAAENVARQFGISRQRQ 99
>UniRef50_A1FU75 Cluster: Acetyl-CoA acetyltransferases; n=5;
Xanthomonadaceae|Rep: Acetyl-CoA acetyltransferases -
Stenotrophomonas maltophilia R551-3
Length = 525
Score = 55.2 bits (127), Expect = 1e-06
Identities = 49/181 (27%), Positives = 84/181 (46%), Gaps = 19/181 (10%)
Frame = +1
Query: 58 IEXAGIPKXXIKXVYIGNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIML 237
+E G+ + V +G V + +A + +GL T T+ + C + + SI+
Sbjct: 140 VERFGLHGQQLGEVAMGAVIKHSSDWNLGREATLSSGLSPLTPGITLQRACGTSLDSIIT 199
Query: 238 AAQGLQTGAQDIILAGGMESMSNVPF-YLK----------RGETSYGGMQ-LVDGIVFD- 378
A + G + + GG ++ S+VP Y K R +++ ++ L G F
Sbjct: 200 VANKIALGQIESGIGGGSDTTSDVPIVYGKKLRARLLAANRAKSTGDKIRALTAGFKFSE 259
Query: 379 ------GLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELV 540
G+ + MG+ E+ AK+ I+R QDE+AV+S+K+ AAAYE F D +
Sbjct: 260 LKPEFPGVAEPRTGKSMGDHCEDMAKEWNISRDSQDEWAVSSHKKLAAAYERGFFSDLIA 319
Query: 541 P 543
P
Sbjct: 320 P 320
>UniRef50_A7IGV8 Cluster: Acetyl-CoA acetyltransferase; n=1;
Xanthobacter autotrophicus Py2|Rep: Acetyl-CoA
acetyltransferase - Xanthobacter sp. (strain Py2)
Length = 376
Score = 54.4 bits (125), Expect = 2e-06
Identities = 40/146 (27%), Positives = 62/146 (42%)
Frame = +1
Query: 67 AGIPKXXIKXVYIGNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQ 246
AGI + V +GN S G A A + AGLP+ T++ C SG+ +I + A
Sbjct: 41 AGIAAAAVDEVILGNALSG--GGNVARVAALAAGLPQHVPALTLDTQCCSGLDAIRMGAA 98
Query: 247 GLQTGAQDIILAGGMESMSNVPFYLKRGETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAE 426
+ G +LAGG+ES S P R F + + + A
Sbjct: 99 RIAAGEARYVLAGGVESFSRAPLRAHRPRNKDEAPAFYRQPAFTPWPE--REPDLAAAAA 156
Query: 427 NTAKKLQITRQDQDEYAVNSYKRSAA 504
A+ I R Q+ +A+ S++R+ A
Sbjct: 157 ELARAEGIPRPAQEAFAMESHRRALA 182
>UniRef50_Q184F9 Cluster: Putative thiolase; n=2; Clostridium
difficile|Rep: Putative thiolase - Clostridium difficile
(strain 630)
Length = 378
Score = 54.0 bits (124), Expect = 3e-06
Identities = 44/153 (28%), Positives = 65/153 (42%)
Frame = +1
Query: 88 IKXVYIGNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQ 267
I + GN + G A + AG+ TV+ CAS M SI +A +++G
Sbjct: 46 IDEIICGN--AVGTGGNIARLMTLTAGVSNEVPAFTVDMQCASAMMSIDIAFSKVKSGQC 103
Query: 268 DIILAGGMESMSNVPFYLKRGETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQ 447
D+I+AGG ES S P + V D ++ M AE A+ Q
Sbjct: 104 DLIIAGGFESSSLQPMRTYHKNDKRYNTNNPNYTVAQFSPDDNSQNSMLEGAERVAELYQ 163
Query: 448 ITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPV 546
I + D D + S+KR+ A E K D + P+
Sbjct: 164 IEKADLDFWVKESHKRAKEAREEKILEDIISPI 196
>UniRef50_A6G214 Cluster: Putative uncharacterized protein; n=1;
Plesiocystis pacifica SIR-1|Rep: Putative
uncharacterized protein - Plesiocystis pacifica SIR-1
Length = 394
Score = 52.8 bits (121), Expect = 6e-06
Identities = 39/129 (30%), Positives = 61/129 (47%), Gaps = 1/129 (0%)
Frame = +1
Query: 196 VNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPFYLKRGETSYGGMQLVDGIVF 375
+++ CA+G ++ A +Q G + L + SN P + GG + V+
Sbjct: 87 ISQACATGAAALAHAGGKVQCGDNEATLVVLADKTSNGPHLVYPNPMGPGGKPDSEDWVW 146
Query: 376 DGLT-DVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPV 552
D + D + K M AEN AK+ I+R++QD V Y++ A +AK +VPV V
Sbjct: 147 DSFSRDPWAKGSMLQTAENVAKEAGISREEQDALTVTRYEQYVAGRDAKFHERYMVPVEV 206
Query: 553 PQKRGAPVI 579
K G VI
Sbjct: 207 --KPGRKVI 213
>UniRef50_A1SKA8 Cluster: Acetyl-CoA acetyltransferases; n=24;
Actinomycetales|Rep: Acetyl-CoA acetyltransferases -
Nocardioides sp. (strain BAA-499 / JS614)
Length = 388
Score = 52.8 bits (121), Expect = 6e-06
Identities = 49/173 (28%), Positives = 77/173 (44%), Gaps = 4/173 (2%)
Frame = +1
Query: 67 AGIPKXXIKXVYIGNVCSAN-LGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIMLAA 243
AGI ++ V G V A +A + AGL + T T ++ C SG +S L
Sbjct: 41 AGIDSELVEQVVGGCVTQAGEQSNDMVRRAWLHAGLAQHTGATAIDAQCGSGQQSAHLVH 100
Query: 244 QGLQTGAQDIILAGGMESMSNVPFYLKRGETSYGGMQLVDGIVFDGLTDVYNKFHMGNCA 423
+ G ++ +A G+E+MS +P G G L D D D+ N+F A
Sbjct: 101 DMVAAGTIEVGVACGVEAMSRIPL----GANVPPG--LGDPRPDDWTIDMPNQF---EAA 151
Query: 424 ENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVP---VPVPQKRGAP 573
+ A+ ITR D D + + S +++ A + F E+ P PV + G+P
Sbjct: 152 DRIARNRGITRADLDAFGLASQQKARVAVDEGRFKREIAPYDAAPVLDEGGSP 204
>UniRef50_Q92GI8 Cluster: Similarity to acetyl-CoA
acetyltransferase; n=2; Rickettsia|Rep: Similarity to
acetyl-CoA acetyltransferase - Rickettsia conorii
Length = 106
Score = 52.4 bits (120), Expect = 8e-06
Identities = 23/58 (39%), Positives = 35/58 (60%)
Frame = +1
Query: 58 IEXAGIPKXXIKXVYIGNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSI 231
++ + I + V +G V + GQ PA Q +I+AG+PK T+NKVC SG+KS+
Sbjct: 39 LQNSKIDPALVGEVILGQVITGGSGQNPARQTLIYAGIPKEVPGYTINKVCGSGLKSV 96
>UniRef50_Q7QZB1 Cluster: GLP_567_7442_8677; n=1; Giardia lamblia
ATCC 50803|Rep: GLP_567_7442_8677 - Giardia lamblia ATCC
50803
Length = 411
Score = 50.8 bits (116), Expect = 2e-05
Identities = 42/153 (27%), Positives = 69/153 (45%), Gaps = 1/153 (0%)
Frame = +1
Query: 88 IKXVYIGNVCSANLGQAPAXQAVIFAGLPKSTI-CTTVNKVCASGMKSIMLAAQGLQTGA 264
+ + +G+ + GQ A Q V + L + + ++N VC SG+++++ A + + G
Sbjct: 54 VSAMVVGHSLPSFCGQHAAQQIVSKSTLLATPVPAISINVVCNSGIEAVIEACRRISVGE 113
Query: 265 QDIILAGGMESMSNVPFYLKRGETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKL 444
LA GMESMS R + + + DGL D + MG+ AE K
Sbjct: 114 GLAYLAVGMESMS-------RAHMVHSNIATDVATIHDGLLDAETQRSMGDIAEEYYSKQ 166
Query: 445 QITRQDQDEYAVNSYKRSAAAYEAKAFVDELVP 543
TRQ + AV S + + A + + EL P
Sbjct: 167 HYTRQQLEAVAVASCEAALARAKPELVHIELDP 199
>UniRef50_Q4TEZ0 Cluster: Chromosome undetermined SCAF4980, whole
genome shotgun sequence; n=1; Tetraodon
nigroviridis|Rep: Chromosome undetermined SCAF4980,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 122
Score = 50.4 bits (115), Expect = 3e-05
Identities = 24/35 (68%), Positives = 27/35 (77%)
Frame = +1
Query: 163 AGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQ 267
+GL ST TT+NKVCASGMKSIM+AAQ L G Q
Sbjct: 1 SGLSLSTPATTINKVCASGMKSIMMAAQSLMCGHQ 35
>UniRef50_Q6MM13 Cluster: Acetyl-CoA acyltransferase; n=2;
Proteobacteria|Rep: Acetyl-CoA acyltransferase -
Bdellovibrio bacteriovorus
Length = 447
Score = 50.4 bits (115), Expect = 3e-05
Identities = 26/75 (34%), Positives = 42/75 (56%)
Frame = +1
Query: 88 IKXVYIGNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQ 267
+ V IGN + + + AG+P T TV++ CAS ++SI + +++G
Sbjct: 51 VDEVIIGNTGNPPDSVNISRVVALNAGIPLKTSAYTVHRNCASALESISNGYEKIKSGTM 110
Query: 268 DIILAGGMESMSNVP 312
D+ILAGG E+MS +P
Sbjct: 111 DVILAGGTENMSQMP 125
Score = 41.1 bits (92), Expect = 0.019
Identities = 20/59 (33%), Positives = 36/59 (61%)
Frame = +1
Query: 370 VFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPV 546
V GLTD + +MG AE AK+ ++R+ QD++A+ S++ ++ A + +E+ PV
Sbjct: 181 VMMGLTDPFVGINMGQTAEILAKEWGLSRETQDKFALRSHQLASKAMKEGRMREEIAPV 239
>UniRef50_Q9KT59 Cluster: 3-ketoacyl-CoA thiolase; n=113;
Proteobacteria|Rep: 3-ketoacyl-CoA thiolase - Vibrio
cholerae
Length = 435
Score = 50.4 bits (115), Expect = 3e-05
Identities = 47/178 (26%), Positives = 79/178 (44%), Gaps = 19/178 (10%)
Frame = +1
Query: 88 IKXVYIGNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQ 267
I+ V G V A + V+ G+ +T +V + CA+ ++ + A+ + G+
Sbjct: 58 IEQVVFGQVVQMPEAPNIAREIVLGTGMSINTDAYSVTRACATSFQAAVNVAESIMAGSI 117
Query: 268 DIILAGGMESMSNVP-----------FYLKRGETSYGGMQLVDGIVFDGLTDV------Y 396
DI +AGG +S S +P L + +T ++L+ + F L V Y
Sbjct: 118 DIGIAGGADSSSVLPIGVSKKLAASLLALSKTKTVGQKLKLLSNLSFKDLMPVPPAVAEY 177
Query: 397 NK-FHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPV-PVPQKR 564
+ MG AE AK I+R +QD A S+ +A A+ DE++ P P K+
Sbjct: 178 STGLSMGQTAEQMAKSYAISRAEQDALAHRSHTLAAQAWAEGKIRDEVMTAFPEPYKK 235
>UniRef50_Q1GUF0 Cluster: Acetyl-CoA C-acyltransferase; n=2;
Proteobacteria|Rep: Acetyl-CoA C-acyltransferase -
Sphingopyxis alaskensis (Sphingomonas alaskensis)
Length = 386
Score = 49.6 bits (113), Expect = 5e-05
Identities = 25/58 (43%), Positives = 35/58 (60%)
Frame = +1
Query: 142 AXQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPF 315
A A + A LP + ++N CASG+ +I LA + +G D+ LAGG+ESMS PF
Sbjct: 69 ALVAKLHADLPDTMAAHSLNNYCASGLTAIGLAVAKVASGEIDVALAGGVESMSAAPF 126
>UniRef50_UPI000023DFFE Cluster: hypothetical protein FG09503.1;
n=1; Gibberella zeae PH-1|Rep: hypothetical protein
FG09503.1 - Gibberella zeae PH-1
Length = 380
Score = 48.8 bits (111), Expect = 9e-05
Identities = 24/82 (29%), Positives = 45/82 (54%)
Frame = +1
Query: 58 IEXAGIPKXXIKXVYIGNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIML 237
++ + I ++ + +G V + G A + AG P+S T+N+ C+SG+++ +
Sbjct: 69 LDRSKINPALVEDLCVGTVLAPGGGATEMRAASLVAGFPESIAVRTLNRQCSSGLQATVD 128
Query: 238 AAQGLQTGAQDIILAGGMESMS 303
A ++TG DI + G+ESMS
Sbjct: 129 VANQIKTGMIDIGIGAGVESMS 150
>UniRef50_Q58944 Cluster: Uncharacterized protein MJ1549; n=18;
Euryarchaeota|Rep: Uncharacterized protein MJ1549 -
Methanococcus jannaschii
Length = 392
Score = 48.0 bits (109), Expect = 2e-04
Identities = 32/87 (36%), Positives = 46/87 (52%), Gaps = 3/87 (3%)
Frame = +1
Query: 58 IEXAGIPKXXIKXVYIGNVCSANL--GQAPAXQAVI-FAGLPKSTICTTVNKVCASGMKS 228
+E AGI I +Y+GN+ SA L GQ + AGL T V CASG +
Sbjct: 34 VEAAGIDGKDIDEMYVGNM-SAGLFVGQEHIASLIAEHAGL-NPIPSTRVEAACASGSLA 91
Query: 229 IMLAAQGLQTGAQDIILAGGMESMSNV 309
+ A + +GA D++L GG+E M++V
Sbjct: 92 LRQAVLNVASGASDVVLVGGVEKMTDV 118
>UniRef50_Q9F8Q0 Cluster: 3-ketoacyl-CoA thiolase; n=1;
Carboxydothermus hydrogenoformans|Rep: 3-ketoacyl-CoA
thiolase - Carboxydothermus hydrogenoformans
Length = 154
Score = 47.6 bits (108), Expect = 2e-04
Identities = 24/61 (39%), Positives = 36/61 (59%)
Frame = +1
Query: 382 LTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPVPQK 561
LTD +K MG AEN + I+R++QDE A S++ + A + F +E+VPV V K
Sbjct: 10 LTDPLHKILMGVTAENLPRTYNISREEQDEIAYRSHQLAVEAIDNGWFTEEIVPVEVNNK 69
Query: 562 R 564
+
Sbjct: 70 K 70
>UniRef50_Q1AV81 Cluster: Thiolase; n=3; Actinobacteria (class)|Rep:
Thiolase - Rubrobacter xylanophilus (strain DSM 9941 /
NBRC 16129)
Length = 394
Score = 46.4 bits (105), Expect = 5e-04
Identities = 39/134 (29%), Positives = 62/134 (46%), Gaps = 3/134 (2%)
Frame = +1
Query: 196 VNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPFYLKRGETSYGGMQLVDGIVF 375
V++ CA+ + + AA + A D L + SN P L + GG ++ V
Sbjct: 87 VSQACATSVACLAAAAA---SAAPDPTLVVAADRTSNGPTLLYPNPSGMGGAPEIEHWVL 143
Query: 376 DGLT-DVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAY-EAKAFVDE-LVPV 546
D D + M AE A + ITR++ DE + Y++ A + +AF +VPV
Sbjct: 144 DAFARDPWAGESMVATAEAVAAEEGITREELDEVTLLRYEQYRDALADGRAFQRRYMVPV 203
Query: 547 PVPQKRGAPVIFAE 588
VP+ RG P++ E
Sbjct: 204 EVPRPRGEPLLLEE 217
>UniRef50_Q565U8 Cluster: 3-oxoacyl-CoA thiolase; n=1; uncultured
bacterium|Rep: 3-oxoacyl-CoA thiolase - uncultured
bacterium
Length = 408
Score = 44.4 bits (100), Expect = 0.002
Identities = 41/148 (27%), Positives = 66/148 (44%), Gaps = 15/148 (10%)
Frame = +1
Query: 196 VNKVCASGMKSIMLAAQ--GLQTGAQD--IILAGGMESMSNVPFYLKRGETSYGGM-QLV 360
V ++CASG ++++ A Q L D I+L G E+MS P ++ S + V
Sbjct: 85 VQRICASGFQTVVNAFQQIALPDAVDDTKIVLCVGAETMSRCPQIIRSPRRSGASFWEFV 144
Query: 361 DG-----IVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAF 525
+G + GL + M A+ ++ +TRQ+ D +A S+ R+ AAY + F
Sbjct: 145 EGGQVEDSMLAGLNHDLAETAMMLTADEYGARMGVTRQECDVFADVSHSRARAAYRSSHF 204
Query: 526 -----VDELVPVPVPQKRGAPVIFAEXE 594
+ + PV G PV A E
Sbjct: 205 NGGDALRGIFPVDAADLSGRPVYLARDE 232
>UniRef50_Q5VKR9 Cluster: Ketoacyl-ACP synthase; n=2;
Saccharopolyspora erythraea|Rep: Ketoacyl-ACP synthase -
Saccharopolyspora erythraea (Streptomyces erythraeus)
Length = 405
Score = 44.0 bits (99), Expect = 0.003
Identities = 18/37 (48%), Positives = 26/37 (70%)
Frame = +1
Query: 187 CTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMES 297
CTTV CASG +++ AAQ ++ G D++LAGG E+
Sbjct: 149 CTTVTTACASGADALVAAAQMIRLGEADVVLAGGAEA 185
>UniRef50_Q1GWY7 Cluster: Acetyl-CoA C-acyltransferase; n=4;
Bacteria|Rep: Acetyl-CoA C-acyltransferase -
Sphingopyxis alaskensis (Sphingomonas alaskensis)
Length = 421
Score = 43.6 bits (98), Expect = 0.004
Identities = 45/160 (28%), Positives = 74/160 (46%), Gaps = 18/160 (11%)
Frame = +1
Query: 124 NLGQAP-AXQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESM 300
NLG + A + + A L + +V C++ M + AA G+ G D+ + GG E M
Sbjct: 58 NLGWSNIARETWLDAKLNPNVPAFSVVLACSTSMTATFAAA-GMLGGGTDLTMVGGAEVM 116
Query: 301 SNVPFYL-----KRGETSYG-----------GMQLVDGIV-FDGLTDVYNKFHMGNCAEN 429
S P L KR + + L D ++ G + MG+ E+
Sbjct: 117 SRPPIALTADASKRLTDLFAQDPAAALAALQSLALHDYVLPTKGWANRITGRTMGDHMED 176
Query: 430 TAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVP 549
TAK +I+R+ QD++A+ S++RS A +E F D + +P
Sbjct: 177 TAKAWRISREAQDDWALKSHQRSVAGWERGFFDDLAISLP 216
>UniRef50_Q8FQ63 Cluster: Putative lipid-transfer protein; n=1;
Corynebacterium efficiens|Rep: Putative lipid-transfer
protein - Corynebacterium efficiens
Length = 361
Score = 43.2 bits (97), Expect = 0.005
Identities = 24/84 (28%), Positives = 40/84 (47%), Gaps = 1/84 (1%)
Frame = +1
Query: 58 IEXAGIPKXXIKXVYIGNVCSANLGQAPAXQAVIFAGLPKSTI-CTTVNKVCASGMKSIM 234
IE +GI I V++GN L ++ L +T+ V CASG +++
Sbjct: 37 IEDSGIDPHEIDAVFVGNFAGQTLTGQGHLGPMVTETLGLTTVPAMRVEGACASGGLALL 96
Query: 235 LAAQGLQTGAQDIILAGGMESMSN 306
A + G D++L GG+E M++
Sbjct: 97 QAVNAIHYGIHDVVLVGGVEKMTH 120
>UniRef50_Q13HG7 Cluster: Acetyl-CoA C-acetyltransferase; n=1;
Burkholderia xenovorans LB400|Rep: Acetyl-CoA
C-acetyltransferase - Burkholderia xenovorans (strain
LB400)
Length = 265
Score = 42.7 bits (96), Expect = 0.006
Identities = 25/89 (28%), Positives = 43/89 (48%), Gaps = 2/89 (2%)
Frame = +1
Query: 151 AVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPFY--LK 324
A I G + VN+ C SG++ ++ A+Q + G +I + GG E+MS P+
Sbjct: 18 AAIEGGCSEGIPAFNVNRRCGSGLRPVISASQSIVPGDTEIAIGGGAENMSRTPYIAAAA 77
Query: 325 RGETSYGGMQLVDGIVFDGLTDVYNKFHM 411
R G ++D ++ L D ++ HM
Sbjct: 78 RWGARMGDSTMID-MMPGALHDPFHGIHM 105
>UniRef50_Q0QMN6 Cluster: Polyketide synthase type I; n=1;
Streptomyces sp. Eco86|Rep: Polyketide synthase type I -
Streptomyces sp. Eco86
Length = 3422
Score = 41.9 bits (94), Expect = 0.011
Identities = 26/73 (35%), Positives = 39/73 (53%), Gaps = 1/73 (1%)
Frame = +1
Query: 100 YIGNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIIL 279
Y+GN NLG + GL + TV+ C+S + ++ LAAQ L++G + L
Sbjct: 1846 YVGN---GNLGSVATGRVAYVLGLTGPAM--TVDTACSSSLVALHLAAQSLRSGESALAL 1900
Query: 280 AGGMESMSN-VPF 315
AGG+ MS+ PF
Sbjct: 1901 AGGVTIMSSPTPF 1913
>UniRef50_Q84FL0 Cluster: AdmM; n=4; Gammaproteobacteria|Rep: AdmM -
Enterobacter agglomerans (Erwinia herbicola) (Pantoea
agglomerans)
Length = 877
Score = 41.5 bits (93), Expect = 0.014
Identities = 28/92 (30%), Positives = 42/92 (45%), Gaps = 1/92 (1%)
Frame = +1
Query: 196 VNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPFYLKRGETSYGGMQLVDGIVF 375
V C+SG+ S+ +A QG+ TG D+ +AGG + +P+ L G GM L + V
Sbjct: 158 VQSACSSGLLSVHMAMQGIATGDCDMAIAGG----ACLPYPLHSGYQFQPGMNLSESGVL 213
Query: 376 DGLTDVYNKFHMG-NCAENTAKKLQITRQDQD 468
+ + G C K L R D+D
Sbjct: 214 SSYSHTADGMVPGFGCVVFVLKSLDKARSDKD 245
>UniRef50_Q1M689 Cluster: Putative thiolase; n=1; Rhizobium
leguminosarum bv. viciae 3841|Rep: Putative thiolase -
Rhizobium leguminosarum bv. viciae (strain 3841)
Length = 143
Score = 41.5 bits (93), Expect = 0.014
Identities = 20/65 (30%), Positives = 37/65 (56%)
Frame = +1
Query: 400 KFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPVPQKRGAPVI 579
+F G+ E + L ++R+DQ +AV S ++A A + E+ V +P+++GAPV+
Sbjct: 53 RFDAGDRRERR-RGLSVSREDQYAFAVRSQAKAAVAQASGRLAKEITSVTIPRRKGAPVV 111
Query: 580 FAEXE 594
+ E
Sbjct: 112 VDKDE 116
>UniRef50_A6GTF1 Cluster: Acetyl-CoA C-acyltransferase; n=1;
Limnobacter sp. MED105|Rep: Acetyl-CoA C-acyltransferase
- Limnobacter sp. MED105
Length = 431
Score = 41.5 bits (93), Expect = 0.014
Identities = 40/203 (19%), Positives = 78/203 (38%), Gaps = 18/203 (8%)
Frame = +1
Query: 1 GRFSXFXXXXXXXXXXXXXIEXAGIPKXXIKXVYIGNVCSANLGQAPAXQAVIFAGLPKS 180
G +S + G+ + V +G V A ++++ AGLP +
Sbjct: 22 GAYSQLMTYELGGKAIAGLVNKTGVDANRVNMVTMGTVLHEIETSNVARESMLSAGLPAT 81
Query: 181 TICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPFY-----------LKR 327
T + S + G D+ +A G+ES S++P +++
Sbjct: 82 IPAYTTSMAGLSASVGFANLCDMIALGRIDVGIAAGVESFSDIPIRYSQKIRRAAMKVRQ 141
Query: 328 GETSYGGMQLVDGIVFDGL-------TDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNS 486
++ ++ + + L TD + MG CAE +K +++R+D D + V S
Sbjct: 142 DSSAKNILKNLASLRPADLKPEMPTGTDFTTRKTMGVCAEQMVQKFKVSREDCDAFTVRS 201
Query: 487 YKRSAAAYEAKAFVDELVPVPVP 555
++ + A ++PV VP
Sbjct: 202 HQLAIEALNKGYLEGTIIPVQVP 224
>UniRef50_A6EZZ3 Cluster: Beta-ketoadipyl CoA thiolase PcaF; n=1;
Marinobacter algicola DG893|Rep: Beta-ketoadipyl CoA
thiolase PcaF - Marinobacter algicola DG893
Length = 127
Score = 41.1 bits (92), Expect = 0.019
Identities = 22/80 (27%), Positives = 46/80 (57%), Gaps = 6/80 (7%)
Frame = +1
Query: 238 AAQGLQTGAQDIILAGGMESMSNVPFYLKRGETSYGGMQLVDG------IVFDGLTDVYN 399
A++ ++ G +++LAGG++SMS+ P+ + + +++Y Q V+G V + Y+
Sbjct: 7 ASRAIRAGEMNLVLAGGVQSMSHEPYVMGKADSTYSRGQPVEGNTIGWRFVNPLMKKQYD 66
Query: 400 KFHMGNCAENTAKKLQITRQ 459
M AE A++ Q++R+
Sbjct: 67 IDSMPETAEKVAEQYQVSRE 86
>UniRef50_UPI00006A0465 Cluster: 3-ketoacyl-CoA thiolase,
peroxisomal precursor (EC 2.3.1.16) (Beta- ketothiolase)
(Acetyl-CoA acyltransferase) (Peroxisomal 3-oxoacyl-CoA
thiolase).; n=1; Xenopus tropicalis|Rep: 3-ketoacyl-CoA
thiolase, peroxisomal precursor (EC 2.3.1.16) (Beta-
ketothiolase) (Acetyl-CoA acyltransferase) (Peroxisomal
3-oxoacyl-CoA thiolase). - Xenopus tropicalis
Length = 329
Score = 40.7 bits (91), Expect = 0.025
Identities = 18/42 (42%), Positives = 29/42 (69%)
Frame = +1
Query: 421 AENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPV 546
+EN A++ ITR+ QD A+ S +R+AAA + F +E+VP+
Sbjct: 150 SENVAERFGITREKQDSLALASQQRAAAAQRSGRFKEEIVPI 191
>UniRef50_Q9KHD6 Cluster: Type II beta-ketoacyl synthase; n=1;
Streptomyces griseus subsp. griseus|Rep: Type II
beta-ketoacyl synthase - Streptomyces griseus subsp.
griseus
Length = 415
Score = 40.7 bits (91), Expect = 0.025
Identities = 22/56 (39%), Positives = 32/56 (57%)
Frame = +1
Query: 127 LGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGME 294
L PA A I G+ + TTV+ C G +I LA + L++G+ D++LAGG E
Sbjct: 138 LAGCPATLAAI--GVGAKGLVTTVSSACVGGHHAIGLALRELRSGSADVVLAGGHE 191
>UniRef50_O28040 Cluster: 3-ketoacyl-CoA thiolase; n=12;
Archaea|Rep: 3-ketoacyl-CoA thiolase - Archaeoglobus
fulgidus
Length = 414
Score = 40.7 bits (91), Expect = 0.025
Identities = 33/129 (25%), Positives = 56/129 (43%), Gaps = 4/129 (3%)
Frame = +1
Query: 157 IFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPFYLKRGET 336
+ A LP V +VC S ++ + G DI++A G E M+++P +
Sbjct: 78 LLAELPVEVPAHGVERVCNSSTTAVHHGTMEIMLGYSDIVIACGFEHMTHLPMQMDLNPH 137
Query: 337 SYGGMQLVDGIVFDGLTDVYNKFHMGNCAE---NTAK-KLQITRQDQDEYAVNSYKRSAA 504
L+ D+ MG AE AK ++ T++D DE+ V S+K +A
Sbjct: 138 IGISPTLMSRTDLIQKYDLMTAMSMGLTAEKLFEVAKDEMGWTKRDLDEWGVRSHKLAAQ 197
Query: 505 AYEAKAFVD 531
A + F++
Sbjct: 198 AVKEGWFLE 206
>UniRef50_O26884 Cluster: Uncharacterized protein MTH_793; n=2;
Euryarchaeota|Rep: Uncharacterized protein MTH_793 -
Methanobacterium thermoautotrophicum
Length = 383
Score = 40.7 bits (91), Expect = 0.025
Identities = 25/86 (29%), Positives = 43/86 (50%), Gaps = 2/86 (2%)
Frame = +1
Query: 58 IEXAGIPKXXIKXVYIGNVCSANLGQAPAXQAVI--FAGLPKSTICTTVNKVCASGMKSI 231
IE AG+ + +Y+GN+ + + ++I AGL T V CASG ++
Sbjct: 34 IEDAGVEGADLDAMYVGNMSAGLFIKQEHISSLIADHAGLTPIP-STRVEAACASGGLAL 92
Query: 232 MLAAQGLQTGAQDIILAGGMESMSNV 309
+ +G DI++A G+E M++V
Sbjct: 93 RSGIMAVASGYHDIVIAAGVEKMTDV 118
>UniRef50_Q9EX53 Cluster: Putative type I polyketide synthase; n=1;
Streptomyces coelicolor|Rep: Putative type I polyketide
synthase - Streptomyces coelicolor
Length = 3576
Score = 40.3 bits (90), Expect = 0.033
Identities = 22/73 (30%), Positives = 39/73 (53%)
Frame = +1
Query: 106 GNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAG 285
G + S N G + + GL + TV+ C+S + ++ +AA L++G D+ LAG
Sbjct: 1933 GYLASGNAGSVASGRVSYNLGLEGPAV--TVDTACSSSLVALHMAANALRSGECDLALAG 1990
Query: 286 GMESMSNVPFYLK 324
G+ MS+ Y++
Sbjct: 1991 GVTVMSSPTSYVE 2003
Score = 36.7 bits (81), Expect = 0.41
Identities = 21/66 (31%), Positives = 35/66 (53%)
Frame = +1
Query: 106 GNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAG 285
G + S + G + + GL T+ TV+ C+S + ++ +AA L++G D+ LAG
Sbjct: 174 GYLFSGSAGSIASGRLAYTFGLEGPTV--TVDTACSSSLVALHMAANALRSGECDLALAG 231
Query: 286 GMESMS 303
G MS
Sbjct: 232 GAAVMS 237
>UniRef50_Q1D6R4 Cluster: Polyketide synthase type I; n=1;
Myxococcus xanthus DK 1622|Rep: Polyketide synthase type
I - Myxococcus xanthus (strain DK 1622)
Length = 2216
Score = 40.3 bits (90), Expect = 0.033
Identities = 20/60 (33%), Positives = 34/60 (56%)
Frame = +1
Query: 118 SANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMES 297
S++L P QAV+ + + T ++ CAS + ++ L + L+ G D+ILAGG+ S
Sbjct: 705 SSDLAPHPTLQAVVTDVVGQGVATTLLDAACASSLYAMALGMKALERGDSDLILAGGVFS 764
>UniRef50_Q0QMP8 Cluster: Polyketide synthase type I; n=1;
Streptomyces aculeolatus|Rep: Polyketide synthase type I
- Streptomyces aculeolatus
Length = 3297
Score = 40.3 bits (90), Expect = 0.033
Identities = 23/67 (34%), Positives = 37/67 (55%)
Frame = +1
Query: 106 GNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAG 285
G V + N G + + GL + TV+ C+S + ++ LAAQ L+TG D+ LAG
Sbjct: 1930 GYVGTGNTGSVASGRVSYAFGLEGPAV--TVDTACSSSLVALHLAAQSLRTGECDMALAG 1987
Query: 286 GMESMSN 306
G+ M++
Sbjct: 1988 GVTVMAS 1994
>UniRef50_A6RBW5 Cluster: Putative uncharacterized protein; n=1;
Ajellomyces capsulatus NAm1|Rep: Putative
uncharacterized protein - Ajellomyces capsulatus NAm1
Length = 228
Score = 40.3 bits (90), Expect = 0.033
Identities = 17/51 (33%), Positives = 32/51 (62%)
Frame = +1
Query: 409 MGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPVPQK 561
+G+ +EN A + I+R+ D++A S++R+ A ++ VDE+ P+ V K
Sbjct: 72 LGHTSENVAGQFNISREKMDDFAARSHQRAELAQKSGWVVDEIAPIRVKVK 122
>UniRef50_Q8U274 Cluster: Acetyl CoA synthase; n=8; Archaea|Rep:
Acetyl CoA synthase - Pyrococcus furiosus
Length = 403
Score = 40.3 bits (90), Expect = 0.033
Identities = 24/85 (28%), Positives = 46/85 (54%), Gaps = 2/85 (2%)
Frame = +1
Query: 58 IEXAGIPKXXIKXVYIGNVCSANLGQAPAXQAVI--FAGLPKSTICTTVNKVCASGMKSI 231
++ AGI K + +Y+GN+ S + + A+I +AGL + CASG ++
Sbjct: 49 MDDAGIDK--VDSLYVGNMASGSFVEQENLGALIADWAGLGNIP-AVKIEAACASGGAAV 105
Query: 232 MLAAQGLQTGAQDIILAGGMESMSN 306
A+ + +G +D++L G+E M++
Sbjct: 106 QEGAKAVLSGLEDVVLVVGVEKMTD 130
>UniRef50_Q3A171 Cluster: 3-oxoacyl-(Acyl-carrier-protein) synthase;
n=1; Pelobacter carbinolicus DSM 2380|Rep:
3-oxoacyl-(Acyl-carrier-protein) synthase - Pelobacter
carbinolicus (strain DSM 2380 / Gra Bd 1)
Length = 395
Score = 39.9 bits (89), Expect = 0.044
Identities = 17/41 (41%), Positives = 26/41 (63%)
Frame = +1
Query: 193 TVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPF 315
TV C+SG ++ +A LQ G D++LAGG + +S VP+
Sbjct: 151 TVVNACSSGSDAVGIAMSWLQQGLCDVVLAGGTDELSMVPY 191
>UniRef50_Q96X18 Cluster: Acetyl-CoA acetyltransferase; n=1;
Laccaria bicolor|Rep: Acetyl-CoA acetyltransferase -
Laccaria bicolor (Bicoloured deceiver) (Laccaria laccata
var.bicolor)
Length = 407
Score = 39.9 bits (89), Expect = 0.044
Identities = 18/46 (39%), Positives = 28/46 (60%)
Frame = +1
Query: 409 MGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPV 546
MG +EN A I R QD ++ S++++AAA +A F E+VP+
Sbjct: 165 MGITSENVAADYHIPRSTQDAFSAKSFQKAAAANKAGKFKSEIVPI 210
Score = 39.5 bits (88), Expect = 0.058
Identities = 17/46 (36%), Positives = 27/46 (58%)
Frame = +1
Query: 88 IKXVYIGNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMK 225
I+ + +GNV G + A A + AG+P T TVN+ C+SG++
Sbjct: 68 IEDIAVGNVLPPGGGASAARMAALHAGIPVETSINTVNRQCSSGLR 113
>UniRef50_Q7NDK9 Cluster: Gll4226 protein; n=1; Gloeobacter
violaceus|Rep: Gll4226 protein - Gloeobacter violaceus
Length = 3029
Score = 39.5 bits (88), Expect = 0.058
Identities = 43/134 (32%), Positives = 64/134 (47%), Gaps = 10/134 (7%)
Frame = +1
Query: 193 TVNKVCASGMKSIMLAAQGLQTGAQDIILAGGME-SMSNVPFYL--KRGETSYGGM---- 351
TV+ CAS + +I LA + L+TG +++AGG++ S P++ K + GG
Sbjct: 879 TVDAACASSLAAIHLAVRDLETGHSAMVIAGGVDTSQGPFPYFCFSKTQALTPGGKPRPF 938
Query: 352 -QLVDGIVF-DGLTDVYNKFHMGNCAENTAKKLQITRQDQDE-YAVNSYKRSAAAYEAKA 522
Q DGIV +GL V K+L +D D YAV K +A + + KA
Sbjct: 939 DQAADGIVIGEGLAMV------------VLKRLADAERDGDRIYAV--IKSTAGSSDGKA 984
Query: 523 FVDELVPVPVPQKR 564
+ P+P QKR
Sbjct: 985 -LGMTAPLPAGQKR 997
>UniRef50_Q3ZXT9 Cluster: 3-oxoacyl-[acyl-carrier-protein] synthase
II; n=5; Chloroflexi|Rep:
3-oxoacyl-[acyl-carrier-protein] synthase II -
Dehalococcoides sp. (strain CBDB1)
Length = 422
Score = 39.5 bits (88), Expect = 0.058
Identities = 22/53 (41%), Positives = 30/53 (56%)
Frame = +1
Query: 148 QAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSN 306
Q I GL S CTT C+SG +I A + ++ G+ I+LAGG ES+ N
Sbjct: 150 QVSIQLGLKGSNFCTT--SACSSGSDAIGTAFEKIRFGSAKIVLAGGAESIMN 200
>UniRef50_A5WF94 Cluster: Acetyl-CoA acetyltransferase; n=72;
Bacteria|Rep: Acetyl-CoA acetyltransferase -
Psychrobacter sp. PRwf-1
Length = 608
Score = 39.5 bits (88), Expect = 0.058
Identities = 37/148 (25%), Positives = 65/148 (43%), Gaps = 17/148 (11%)
Frame = +1
Query: 148 QAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPF---- 315
++ + L T V++ C +G+++ A+ + G D + GG+++ S+ P
Sbjct: 251 ESALNTALDPQTPAYDVSQACGTGLQATFAASNKIALGIIDSAITGGVDTTSDAPIAVGD 310
Query: 316 -----YLKRGETSYGGMQL--VDGIVFDGLTDVYNK------FHMGNCAENTAKKLQITR 456
+K G +L + I L D MG+ TA + I+R
Sbjct: 311 GLRKALIKLGAARNNKQRLSALTSINPKELIDAPQNGEPRTGLSMGDHQAITALEWNISR 370
Query: 457 QDQDEYAVNSYKRSAAAYEAKAFVDELV 540
+ QDE AV S++ A AYE + F D+L+
Sbjct: 371 EAQDELAVKSHQNLARAYE-EGFFDDLI 397
>UniRef50_A2W1N2 Cluster: Acetyl-CoA acetyltransferase; n=6;
Proteobacteria|Rep: Acetyl-CoA acetyltransferase -
Burkholderia cenocepacia PC184
Length = 434
Score = 39.5 bits (88), Expect = 0.058
Identities = 26/84 (30%), Positives = 40/84 (47%), Gaps = 2/84 (2%)
Frame = +1
Query: 58 IEXAGIPKXXIKXVYIGNVCSANL-GQAPAXQAVIFAGLPKSTICT-TVNKVCASGMKSI 231
+ AG I+ + + + L GQ V+F+ + I V CASG ++
Sbjct: 55 LRDAGCHTDAIRAAFYAGITNGPLQGQLSIPGQVVFSKIGLEGIPVFNVENACASGSTAV 114
Query: 232 MLAAQGLQTGAQDIILAGGMESMS 303
LA + LQ+GA D+ LA G E M+
Sbjct: 115 HLAVRELQSGACDVALALGAEKMN 138
>UniRef50_Q1MX72 Cluster: Type I polyketide synthase; n=2;
Streptomyces sp. NRRL 11266|Rep: Type I polyketide
synthase - Streptomyces sp. NRRL 11266
Length = 5963
Score = 39.1 bits (87), Expect = 0.077
Identities = 26/69 (37%), Positives = 40/69 (57%)
Frame = +1
Query: 100 YIGNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIIL 279
Y+GN +A++ A A F GL + TV+ C+S + ++ LAAQ L+ G D+ L
Sbjct: 2244 YLGNGSAASV--ASGRVAYTF-GLEGPAV--TVDTACSSSLVALHLAAQALRNGECDLAL 2298
Query: 280 AGGMESMSN 306
AGG+ MS+
Sbjct: 2299 AGGVTVMSS 2307
Score = 35.1 bits (77), Expect = 1.3
Identities = 16/37 (43%), Positives = 24/37 (64%)
Frame = +1
Query: 193 TVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMS 303
TV+ C+S + ++ LAAQ L+ G D+ LAGG M+
Sbjct: 4337 TVDTACSSSLVALHLAAQALRNGECDLALAGGATIMA 4373
Score = 33.5 bits (73), Expect = 3.8
Identities = 16/37 (43%), Positives = 24/37 (64%)
Frame = +1
Query: 193 TVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMS 303
TV+ C+S + S+ LAAQ L+ D+ LAGG+ M+
Sbjct: 202 TVDTACSSSLVSMHLAAQALRNEECDLALAGGVTVMA 238
>UniRef50_Q0P7K1 Cluster: Putative hybrid non-ribosomal
peptide-polyketide synthetase; n=5;
Enterobacteriaceae|Rep: Putative hybrid non-ribosomal
peptide-polyketide synthetase - Escherichia coli
Length = 2154
Score = 39.1 bits (87), Expect = 0.077
Identities = 22/63 (34%), Positives = 34/63 (53%), Gaps = 1/63 (1%)
Frame = +1
Query: 187 CTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGME-SMSNVPFYLKRGETSYGGMQLVD 363
C TV CA+ + ++ LA +GL +G D+ LAGG+ M Y G+ G+Q D
Sbjct: 160 CVTVQASCATSLVAVHLACEGLLSGQCDMALAGGVTFRMEEQRSYESHGD----GLQAED 215
Query: 364 GIV 372
G++
Sbjct: 216 GLI 218
>UniRef50_A3N0P7 Cluster: 3-ketoacyl-CoA thiolase; n=1;
Actinobacillus pleuropneumoniae L20|Rep: 3-ketoacyl-CoA
thiolase - Actinobacillus pleuropneumoniae serotype 5b
(strain L20)
Length = 434
Score = 39.1 bits (87), Expect = 0.077
Identities = 39/160 (24%), Positives = 70/160 (43%), Gaps = 19/160 (11%)
Frame = +1
Query: 139 PAXQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVP-- 312
PA + + +PK +++ C SG+++I A + +G+ +AGG +S+SN P
Sbjct: 75 PAREIALALNMPKLQ-SYSISSSCLSGLQAIANVAGSIVSGSISAGIAGGADSISNAPLS 133
Query: 313 ------------FYLKRGETSYGGMQLVDGIVFD----GLTDVYNKFHMGNCAENTAKKL 444
F + E Y + L D + + +E A+
Sbjct: 134 ISPRVIYKLKSIFNAETLEEKYRRFRHFSWRDLKPHGVNLRDFTTQMSVAEVSEQMAQDN 193
Query: 445 QITRQDQDEYAVNSYKRSAAAYEAKAFVDELVP-VPVPQK 561
I+R +QDEYA S +R++ A++ +E++P P P K
Sbjct: 194 HISRAEQDEYARLSNQRASDAWKIGLLKEEVMPSFPRPYK 233
>UniRef50_UPI0000DADC27 Cluster: hypothetical protein
RcanM_01000901; n=1; Rickettsia canadensis str.
McKiel|Rep: hypothetical protein RcanM_01000901 -
Rickettsia canadensis str. McKiel
Length = 62
Score = 38.7 bits (86), Expect = 0.10
Identities = 19/52 (36%), Positives = 28/52 (53%), Gaps = 1/52 (1%)
Frame = +1
Query: 127 LGQAPAXQAVIFA-GLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIIL 279
+ Q PA Q +I A +S +NKVC SG KS++L A + G I++
Sbjct: 1 MAQNPASQTLIHARNTERSAGLYAINKVCGSGFKSVVLTANSIMIGYNKIVM 52
>UniRef50_Q93HI8 Cluster: Modular polyketide synthase; n=1;
Streptomyces avermitilis|Rep: Modular polyketide synthase
- Streptomyces avermitilis
Length = 3970
Score = 38.7 bits (86), Expect = 0.10
Identities = 21/66 (31%), Positives = 36/66 (54%)
Frame = +1
Query: 106 GNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAG 285
G + + + G + + GL + T++ C+S + ++ LAAQ L+TG D+ LAG
Sbjct: 1977 GFIGTGSAGSVASGRIAFTLGLEGPAV--TLDTACSSSLVALHLAAQALRTGECDLALAG 2034
Query: 286 GMESMS 303
G+ MS
Sbjct: 2035 GVTVMS 2040
>UniRef50_Q5WBW0 Cluster: Acetyl-CoA acetyltransferase; n=1;
Bacillus clausii KSM-K16|Rep: Acetyl-CoA
acetyltransferase - Bacillus clausii (strain KSM-K16)
Length = 378
Score = 38.7 bits (86), Expect = 0.10
Identities = 27/85 (31%), Positives = 39/85 (45%), Gaps = 1/85 (1%)
Frame = +1
Query: 58 IEXAGIPKXXIKXVYIGNVCSANLGQAPAXQAVIFAGLPKSTI-CTTVNKVCASGMKSIM 234
+ AG PK I V++GN L Q A++ L I V CASG +
Sbjct: 33 LTAAGRPK--IDAVFVGNFLGGALSQQEILGAILANELGLGPIPAMKVEGACASGGIAFR 90
Query: 235 LAAQGLQTGAQDIILAGGMESMSNV 309
A Q ++ G + +L G+E M+NV
Sbjct: 91 QAYQLIKAGEYNAVLVAGVEKMTNV 115
>UniRef50_Q84HM3 Cluster: PksE; n=1; Lechevalieria
aerocolonigenes|Rep: PksE - Nocardia aerocolonigenes
(Lechevalieria aerocolonigenes)
Length = 1892
Score = 38.7 bits (86), Expect = 0.10
Identities = 20/61 (32%), Positives = 38/61 (62%), Gaps = 4/61 (6%)
Frame = +1
Query: 193 TVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPF----YLKRGETSYGGMQLV 360
TV+ C+S + +++ A + L+ G+ D++LAGG++ +S PF + K G + G M++
Sbjct: 212 TVDGACSSALLAVVTACRSLRDGSADVVLAGGVD-LSVDPFELVGFAKTGALTAGPMRVY 270
Query: 361 D 363
D
Sbjct: 271 D 271
>UniRef50_Q6V1M7 Cluster: Plm2-3; n=1; Streptomyces sp. HK803|Rep:
Plm2-3 - Streptomyces sp. HK803
Length = 3362
Score = 38.7 bits (86), Expect = 0.10
Identities = 17/44 (38%), Positives = 28/44 (63%)
Frame = +1
Query: 193 TVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPFYLK 324
TV+ C+S + S+ LA Q L+ G D+ LAGG+ M+ F+++
Sbjct: 205 TVDTACSSSLVSLHLACQSLRAGECDLALAGGVAIMAGPTFFVE 248
Score = 32.7 bits (71), Expect = 6.7
Identities = 14/44 (31%), Positives = 27/44 (61%)
Frame = +1
Query: 193 TVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPFYLK 324
T++ C+S + ++ LA Q L+ G D+ LAGG M++ +++
Sbjct: 1923 TLDTACSSSLVALHLACQALRRGECDLALAGGATVMASPHIFVE 1966
>UniRef50_Q3D2X0 Cluster: Thiolase; n=7; Streptococcus
agalactiae|Rep: Thiolase - Streptococcus agalactiae H36B
Length = 371
Score = 38.7 bits (86), Expect = 0.10
Identities = 30/125 (24%), Positives = 54/125 (43%)
Frame = +1
Query: 193 TVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPFYLKRGETSYGGMQLVDGIV 372
T++ CAS ++ + TG + +L GG+ES S P E + G + V
Sbjct: 81 TIDMQCASSSSALFFGYLKISTGINEKVLVGGIESSSLQPMRRYAKEDNRNG----EYTV 136
Query: 373 FDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPV 552
D Y + M A+ +K R+ D+ A S+KR+ A + + ++P+
Sbjct: 137 AQFSPDSYAETVMLEGAQRVCQKYGFRREMLDKLAFLSHKRALTAKQGGYLEEVILPMEG 196
Query: 553 PQKRG 567
+ +G
Sbjct: 197 MRDQG 201
>UniRef50_Q1MX73 Cluster: Type I polyketide synthase; n=1;
Streptomyces sp. NRRL 11266|Rep: Type I polyketide
synthase - Streptomyces sp. NRRL 11266
Length = 5657
Score = 38.3 bits (85), Expect = 0.13
Identities = 27/75 (36%), Positives = 41/75 (54%)
Frame = +1
Query: 100 YIGNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIIL 279
Y+GN +A++ A A F GL + TV+ C+S + + LAAQ L+ G D+ L
Sbjct: 4004 YLGNGSAASV--ASGRVAYTF-GLEGPAM--TVDTACSSSLVGMHLAAQALRNGECDLAL 4058
Query: 280 AGGMESMSNVPFYLK 324
AGG+ MS +L+
Sbjct: 4059 AGGVTVMSTPSAFLE 4073
Score = 33.9 bits (74), Expect = 2.9
Identities = 20/67 (29%), Positives = 32/67 (47%)
Frame = +1
Query: 106 GNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAG 285
G + + G + + GL + TV+ C+S + ++ LA Q L+ G D LAG
Sbjct: 173 GYAATGSAGSVASGRVAYTFGLEGPAV--TVDTACSSSLVALHLAIQALRNGECDSALAG 230
Query: 286 GMESMSN 306
G MS+
Sbjct: 231 GATVMSS 237
Score = 33.5 bits (73), Expect = 3.8
Identities = 19/66 (28%), Positives = 33/66 (50%)
Frame = +1
Query: 106 GNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAG 285
G + + + G + + GL + TV+ C+S + ++ LA Q L+ G D+ LAG
Sbjct: 2254 GYIATGSSGSVASGRIAYTFGLEGPAM--TVDTACSSSLVALHLAMQALRNGECDLALAG 2311
Query: 286 GMESMS 303
G M+
Sbjct: 2312 GATIMA 2317
>UniRef50_Q0QMQ1 Cluster: Polyketide synthase type I; n=1;
Streptomyces aculeolatus|Rep: Polyketide synthase type I
- Streptomyces aculeolatus
Length = 4308
Score = 38.3 bits (85), Expect = 0.13
Identities = 22/55 (40%), Positives = 34/55 (61%), Gaps = 4/55 (7%)
Frame = +1
Query: 193 TVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSN----VPFYLKRGETSYG 345
TV+ C+S + ++ LAAQ L+TG D+ LAGG+ M+ V F +RG ++ G
Sbjct: 2946 TVDTACSSSLVALHLAAQSLRTGECDMALAGGVTVMAGPGTFVEFSRQRGLSADG 3000
Score = 34.3 bits (75), Expect = 2.2
Identities = 15/44 (34%), Positives = 27/44 (61%)
Frame = +1
Query: 193 TVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPFYLK 324
TV+ C+S + ++ LAAQ ++ G D LAGG+ +S +++
Sbjct: 1222 TVDTACSSSLVALHLAAQSIRAGECDTALAGGVTVLSTPGMFVE 1265
>UniRef50_Q09DD1 Cluster: Type I polyketide synthase PikAI; n=1;
Stigmatella aurantiaca DW4/3-1|Rep: Type I polyketide
synthase PikAI - Stigmatella aurantiaca DW4/3-1
Length = 950
Score = 38.3 bits (85), Expect = 0.13
Identities = 27/92 (29%), Positives = 38/92 (41%)
Frame = +1
Query: 193 TVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPFYLKRGETSYGGMQLVDGIV 372
TV CAS + ++ L+ QGL+ G D LAGG+ S P+ + + G G
Sbjct: 693 TVESACASTLAALSLSIQGLRDGRWDAALAGGVWSQITAPYCV---NMCFVGAVSPTGET 749
Query: 373 FDGLTDVYNKFHMGNCAENTAKKLQITRQDQD 468
D H C K+L R+D D
Sbjct: 750 RPFSKDADGFVHGEGCGMFVLKRLSDARRDGD 781
>UniRef50_A4KCE5 Cluster: Tautomycetin biosynthetic PKS; n=1;
Streptomyces sp. CK4412|Rep: Tautomycetin biosynthetic
PKS - Streptomyces sp. CK4412
Length = 7620
Score = 38.3 bits (85), Expect = 0.13
Identities = 23/82 (28%), Positives = 43/82 (52%)
Frame = +1
Query: 106 GNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAG 285
G++ + G A + + GL + +V+ C+S + ++ LAAQ L+ G + LAG
Sbjct: 2247 GHLITGTAGSAISGRVAYALGLEGPAV--SVDTACSSSLVAMHLAAQALRAGECSLALAG 2304
Query: 286 GMESMSNVPFYLKRGETSYGGM 351
G+ M+ ++ G T+ GG+
Sbjct: 2305 GVTVMATADAFV--GFTAQGGL 2324
Score = 37.9 bits (84), Expect = 0.18
Identities = 21/53 (39%), Positives = 31/53 (58%)
Frame = +1
Query: 193 TVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPFYLKRGETSYGGM 351
+V+ C+S M S+ LAAQ L+ G + LAGG+ M+ ++ G T GGM
Sbjct: 5996 SVDTACSSSMVSMHLAAQALRAGECSLALAGGVTVMAEPDVFI--GFTVQGGM 6046
Score = 32.3 bits (70), Expect = 8.8
Identities = 18/66 (27%), Positives = 33/66 (50%)
Frame = +1
Query: 106 GNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAG 285
G+ + G + + GL + +V+ C+S + ++ LAAQ L+ G + LAG
Sbjct: 217 GHAFTGGAGSVTSGRVAYTLGLEGPAV--SVDTACSSSLVAMHLAAQALRAGECTLALAG 274
Query: 286 GMESMS 303
G+ M+
Sbjct: 275 GVTVMA 280
>UniRef50_Q5XDB2 Cluster: Acetyl-CoA acetyltransferase; n=11;
Streptococcus pyogenes|Rep: Acetyl-CoA acetyltransferase
- Streptococcus pyogenes serotype M6
Length = 384
Score = 37.9 bits (84), Expect = 0.18
Identities = 31/139 (22%), Positives = 61/139 (43%), Gaps = 2/139 (1%)
Frame = +1
Query: 157 IFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPFYLKRGET 336
+++ L +S TV+ CAS ++ + ++ G +L GG+ES S P E+
Sbjct: 68 LYSHLGESVSALTVDMQCASAGAALSVGYAKIKAGMASNLLVGGIESSSLQP------ES 121
Query: 337 SYGGMQLVDGI--VFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAY 510
Y G V D + F M AE A++ T++ + + + S+++++
Sbjct: 122 VYASADWRQGAYKVAQFSPDSISPFAMIEGAERVAREHGFTKEYLNHWTLRSHQKASYCQ 181
Query: 511 EAKAFVDELVPVPVPQKRG 567
E D ++ +P +G
Sbjct: 182 EQALLADLILDLPGASDQG 200
>UniRef50_Q9L8C7 Cluster: Polyketide synthase; n=8; Sorangium
cellulosum|Rep: Polyketide synthase - Polyangium
cellulosum (Sorangium cellulosum)
Length = 7257
Score = 37.9 bits (84), Expect = 0.18
Identities = 15/38 (39%), Positives = 25/38 (65%)
Frame = +1
Query: 187 CTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESM 300
C TV+ C+S + +I LA + L+ G D+ LAGG+ ++
Sbjct: 198 CLTVDTACSSSLVAIHLACRSLRAGESDLALAGGVSAL 235
>UniRef50_Q83WF0 Cluster: Protomycinolide IV synthase 1; n=18;
cellular organisms|Rep: Protomycinolide IV synthase 1 -
Micromonospora griseorubida
Length = 4307
Score = 37.9 bits (84), Expect = 0.18
Identities = 21/68 (30%), Positives = 35/68 (51%)
Frame = +1
Query: 100 YIGNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIIL 279
Y G++ + G + + GL + TV+ C+S + +I LA Q L+ G D+ L
Sbjct: 2613 YEGHLLTGTSGSVASGRVSYVLGLEGPAV--TVDTACSSSLVAIHLAVQALRAGECDLAL 2670
Query: 280 AGGMESMS 303
AGG+ M+
Sbjct: 2671 AGGVTVMA 2678
Score = 36.7 bits (81), Expect = 0.41
Identities = 21/58 (36%), Positives = 33/58 (56%)
Frame = +1
Query: 193 TVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPFYLKRGETSYGGMQLVDG 366
TV+ C+S + ++ LA Q L++G D+ LAGG+ M+ ++ E S G VDG
Sbjct: 1153 TVDTACSSSLVALHLAVQALRSGECDVALAGGVTVMATPGIFV---EFSRQGGLAVDG 1207
>UniRef50_Q3W1C5 Cluster: Beta-ketoacyl synthase:Acyl transferase
domain:Phosphopantetheine- binding domain; n=1; Frankia
sp. EAN1pec|Rep: Beta-ketoacyl synthase:Acyl transferase
domain:Phosphopantetheine- binding domain - Frankia sp.
EAN1pec
Length = 1392
Score = 37.9 bits (84), Expect = 0.18
Identities = 17/44 (38%), Positives = 29/44 (65%)
Frame = +1
Query: 193 TVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPFYLK 324
TV+ C+S + ++ LAAQ L++G D+ LAGG+ M+ +L+
Sbjct: 249 TVDTACSSSLVALHLAAQALRSGECDLALAGGVTVMATPGMFLE 292
>UniRef50_A5IHN4 Cluster: 3-oxoacyl-(Acyl carrier protein) synthase
II, C-terminal; n=4; Legionella pneumophila|Rep:
3-oxoacyl-(Acyl carrier protein) synthase II, C-terminal
- Legionella pneumophila (strain Corby)
Length = 430
Score = 37.9 bits (84), Expect = 0.18
Identities = 17/39 (43%), Positives = 27/39 (69%)
Frame = +1
Query: 190 TTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSN 306
++V+ CASG +++ LA Q ++ G D +LAGG +SM N
Sbjct: 170 SSVHTACASGGQALGLAMQVIRRGEADFMLAGGFDSMIN 208
>UniRef50_Q7WTF3 Cluster: NanA3; n=1; Streptomyces nanchangensis|Rep:
NanA3 - Streptomyces nanchangensis
Length = 4032
Score = 37.5 bits (83), Expect = 0.23
Identities = 21/68 (30%), Positives = 36/68 (52%)
Frame = +1
Query: 100 YIGNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIIL 279
Y G + + + + + GL T+ TV+ C+S + ++ LAAQ L+ G D+ L
Sbjct: 2013 YEGQIMTGSTPSVASGRVAYTFGLEGPTL--TVDTACSSSLVAMHLAAQALRQGECDLAL 2070
Query: 280 AGGMESMS 303
AGG+ M+
Sbjct: 2071 AGGVTVMA 2078
Score = 33.5 bits (73), Expect = 3.8
Identities = 15/37 (40%), Positives = 25/37 (67%)
Frame = +1
Query: 193 TVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMS 303
TV+ C+S + ++ LAAQ L+ G ++ LAGG+ M+
Sbjct: 207 TVDTACSSSLVAMHLAAQALRQGECELALAGGVTVMT 243
>UniRef50_Q6JHN6 Cluster: ObsC; n=1; Saccharopolyspora spinosa|Rep:
ObsC - Saccharopolyspora spinosa
Length = 7488
Score = 37.5 bits (83), Expect = 0.23
Identities = 17/37 (45%), Positives = 26/37 (70%)
Frame = +1
Query: 193 TVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMS 303
TV+ C+S + ++ LAAQ L++G D+ LAGG+ MS
Sbjct: 1935 TVDTACSSSLVALHLAAQALRSGECDLALAGGVTVMS 1971
Score = 35.9 bits (79), Expect = 0.72
Identities = 19/66 (28%), Positives = 35/66 (53%)
Frame = +1
Query: 106 GNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAG 285
G + + N G + + GL + T++ C+S + ++ LA Q L++G D+ LAG
Sbjct: 204 GYLATGNAGGVMSGRLAYTFGLEGPAV--TIDTACSSSLVALHLAGQALRSGECDLALAG 261
Query: 286 GMESMS 303
G+ M+
Sbjct: 262 GVTVMA 267
Score = 34.3 bits (75), Expect = 2.2
Identities = 15/37 (40%), Positives = 24/37 (64%)
Frame = +1
Query: 193 TVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMS 303
TV+ C+S + ++ LA Q L++G D+ L GG+ MS
Sbjct: 3936 TVDTACSSSLVALHLAGQALRSGECDLALVGGVTVMS 3972
Score = 34.3 bits (75), Expect = 2.2
Identities = 18/73 (24%), Positives = 36/73 (49%)
Frame = +1
Query: 106 GNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAG 285
G++ + N + + GL + TV+ C+S + ++ LA Q L +G D+ L G
Sbjct: 5648 GHIGTGNTASVMSGRLAYTFGLEGPAV--TVDTACSSSLVALHLAVQALSSGECDLALVG 5705
Query: 286 GMESMSNVPFYLK 324
G+ M+ +++
Sbjct: 5706 GVTVMATPALFVE 5718
>UniRef50_Q4U446 Cluster: DszB; n=2; cellular organisms|Rep: DszB -
Polyangium cellulosum (Sorangium cellulosum)
Length = 6256
Score = 37.5 bits (83), Expect = 0.23
Identities = 17/42 (40%), Positives = 27/42 (64%)
Frame = +1
Query: 187 CTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVP 312
C V+ CAS + +I LA +GL G D+ +AGG+ ++S +P
Sbjct: 5662 CMAVDTTCASSLTAIHLACEGLLLGRTDLAIAGGV-NLSLIP 5702
>UniRef50_Q0VZ72 Cluster: Polyketide synthase; n=1; Chondromyces
crocatus|Rep: Polyketide synthase - Chondromyces
crocatus
Length = 2198
Score = 37.5 bits (83), Expect = 0.23
Identities = 16/38 (42%), Positives = 24/38 (63%)
Frame = +1
Query: 187 CTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESM 300
C TV+ C+S + S+ LA + L+ G D+ LAGG+ M
Sbjct: 194 CMTVDTACSSSLVSVHLACRSLRAGECDLALAGGVNLM 231
>UniRef50_A7HT85 Cluster: Beta-ketoacyl synthase; n=1; Parvibaculum
lavamentivorans DS-1|Rep: Beta-ketoacyl synthase -
Parvibaculum lavamentivorans DS-1
Length = 390
Score = 37.5 bits (83), Expect = 0.23
Identities = 21/51 (41%), Positives = 31/51 (60%)
Frame = +1
Query: 148 QAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESM 300
QAV AG P C V+ C SG K+I+ AA+ LQ G D ++ GG++++
Sbjct: 143 QAVTGAGGP----CYGVSTACTSGGKAIVSAARLLQAGLCDAVITGGVDTL 189
>UniRef50_A6E0C0 Cluster: Putative uncharacterized protein; n=1;
Roseovarius sp. TM1035|Rep: Putative uncharacterized
protein - Roseovarius sp. TM1035
Length = 595
Score = 37.5 bits (83), Expect = 0.23
Identities = 24/71 (33%), Positives = 35/71 (49%), Gaps = 1/71 (1%)
Frame = +1
Query: 106 GNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAG 285
GN AN Q A I L + T++ C+SG ++ LA L+ G D+ LAG
Sbjct: 124 GNPHCANGAQNAAISGRISYCLGLTGPSLTIDTACSSGAAAVALAGDNLRLGHCDVALAG 183
Query: 286 GMESMSNV-PF 315
G+ ++ V PF
Sbjct: 184 GVNALLTVEPF 194
>UniRef50_Q9HRI8 Cluster: 3-ketoacyl-CoA thiolase; n=5;
Halobacteriaceae|Rep: 3-ketoacyl-CoA thiolase -
Halobacterium salinarium (Halobacterium halobium)
Length = 395
Score = 37.5 bits (83), Expect = 0.23
Identities = 21/85 (24%), Positives = 39/85 (45%), Gaps = 1/85 (1%)
Frame = +1
Query: 58 IEXAGIPKXXIKXVYIGNVCSANLGQAPAXQAVIFA-GLPKSTICTTVNKVCASGMKSIM 234
++ AG+ + + V+ GN L + Q + A L T CAS ++
Sbjct: 34 LDDAGVAREDVAAVHYGNFMG-ELSEHQGHQGPLVAEALGLDVPATRYESACASSGVALR 92
Query: 235 LAAQGLQTGAQDIILAGGMESMSNV 309
A + ++ G D+++ GG E M+N+
Sbjct: 93 RAVRDVRNGEADVVVVGGAERMNNL 117
>UniRef50_Q9ZGI4 Cluster: Type I polyketide synthase PikAII; n=2;
Streptomyces venezuelae|Rep: Type I polyketide synthase
PikAII - Streptomyces venezuelae
Length = 3739
Score = 37.1 bits (82), Expect = 0.31
Identities = 21/66 (31%), Positives = 34/66 (51%)
Frame = +1
Query: 106 GNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAG 285
G + + N G + + GL + TV+ C+S + ++ LA Q L+ G D+ LAG
Sbjct: 176 GYLGTGNSGSVASGRVAYTLGLEGPAV--TVDTACSSSLVALHLAVQALRKGEVDMALAG 233
Query: 286 GMESMS 303
G+ MS
Sbjct: 234 GVTVMS 239
Score = 32.3 bits (70), Expect = 8.8
Identities = 15/37 (40%), Positives = 23/37 (62%)
Frame = +1
Query: 193 TVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMS 303
TV+ C+S + ++ LA Q L+ G + LAGG+ MS
Sbjct: 1707 TVDTACSSSLVALHLAVQALRKGECGLALAGGVTVMS 1743
>UniRef50_Q93NX9 Cluster: AmphI; n=5; Bacteria|Rep: AmphI -
Streptomyces nodosus
Length = 9510
Score = 37.1 bits (82), Expect = 0.31
Identities = 21/58 (36%), Positives = 33/58 (56%)
Frame = +1
Query: 193 TVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPFYLKRGETSYGGMQLVDG 366
TV+ C+S + ++ LA Q L+ G + LAGG+ MS +++ G GG+ VDG
Sbjct: 190 TVDTACSSSLVAVHLATQALRAGECTLALAGGVTVMSGPGTFIEMGR--QGGLS-VDG 244
Score = 33.1 bits (72), Expect = 5.0
Identities = 15/37 (40%), Positives = 22/37 (59%)
Frame = +1
Query: 193 TVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMS 303
T++ C+S + +I LA Q L+ G + LAGG MS
Sbjct: 5020 TLDTACSSSLVAIHLACQSLRNGESTLALAGGASIMS 5056
Score = 33.1 bits (72), Expect = 5.0
Identities = 15/37 (40%), Positives = 25/37 (67%)
Frame = +1
Query: 193 TVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMS 303
+V+ C+S + ++ LAAQ L++G I LAGG+ M+
Sbjct: 8096 SVDTACSSSLVALHLAAQALRSGECSIALAGGVTVMA 8132
>UniRef50_Q5VKQ8 Cluster: Type I PKS; n=3; Saccharopolyspora
erythraea|Rep: Type I PKS - Saccharopolyspora erythraea
(Streptomyces erythraeus)
Length = 3481
Score = 37.1 bits (82), Expect = 0.31
Identities = 23/68 (33%), Positives = 34/68 (50%)
Frame = +1
Query: 100 YIGNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIIL 279
Y+GN NLG + + GL + TV+ C+S + ++ LAAQ L+ G + L
Sbjct: 1871 YLGN---GNLGSVASGRVAYTFGLEGPAV--TVDTACSSSLVALHLAAQSLRAGECSMAL 1925
Query: 280 AGGMESMS 303
GG MS
Sbjct: 1926 VGGATVMS 1933
>UniRef50_Q52V50 Cluster: Polyketide synthase type I; n=7; cellular
organisms|Rep: Polyketide synthase type I - Streptomyces
aizunensis
Length = 7510
Score = 37.1 bits (82), Expect = 0.31
Identities = 21/55 (38%), Positives = 32/55 (58%), Gaps = 4/55 (7%)
Frame = +1
Query: 193 TVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSN----VPFYLKRGETSYG 345
TV+ C+S + ++ LAAQ L+ G D+ LAGG+ MS + F +RG + G
Sbjct: 2001 TVDTACSSSLVALHLAAQALRNGECDMALAGGVTVMSTPDTFIDFSRQRGLSGNG 2055
>UniRef50_Q3W1F1 Cluster: Beta-ketoacyl synthase:Acyl transferase
domain; n=1; Frankia sp. EAN1pec|Rep: Beta-ketoacyl
synthase:Acyl transferase domain - Frankia sp. EAN1pec
Length = 2816
Score = 37.1 bits (82), Expect = 0.31
Identities = 16/43 (37%), Positives = 28/43 (65%)
Frame = +1
Query: 193 TVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPFYL 321
TV+ CAS + ++ A + L GA D++L GG+++ S+V +L
Sbjct: 951 TVDAACASSLAALDAACKELSAGASDMVLCGGVDTHSSVHDFL 993
>UniRef50_Q27W58 Cluster: NigAVII; n=6; cellular organisms|Rep:
NigAVII - Streptomyces violaceoniger
Length = 4787
Score = 37.1 bits (82), Expect = 0.31
Identities = 21/66 (31%), Positives = 35/66 (53%)
Frame = +1
Query: 106 GNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAG 285
G V + N+G + + GL + TV+ C+S + ++ LAAQ L+ G + LAG
Sbjct: 3304 GYVATGNIGSVVSGRVAYSFGLEGPAV--TVDTACSSSLVAMHLAAQALRQGECTMALAG 3361
Query: 286 GMESMS 303
G+ M+
Sbjct: 3362 GVTVMA 3367
Score = 34.7 bits (76), Expect = 1.7
Identities = 17/42 (40%), Positives = 27/42 (64%), Gaps = 1/42 (2%)
Frame = +1
Query: 193 TVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSN-VPF 315
TV+ C+S + ++ LA Q ++ G D+ LAGG+ MS+ PF
Sbjct: 202 TVDTACSSSLVAMHLACQAIRQGECDMALAGGVAVMSSTAPF 243
Score = 32.3 bits (70), Expect = 8.8
Identities = 20/55 (36%), Positives = 31/55 (56%), Gaps = 4/55 (7%)
Frame = +1
Query: 193 TVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSN----VPFYLKRGETSYG 345
TV+ C+S + ++ LAAQ L+ G + LAGG+ M+ V F +RG + G
Sbjct: 1764 TVDTACSSSLVAMHLAAQALRQGECTMALAGGVTVMATPTTFVEFSRQRGLAADG 1818
>UniRef50_Q0RTS5 Cluster: Putative Type I modular polyketide synthase;
n=1; Frankia alni ACN14a|Rep: Putative Type I modular
polyketide synthase - Frankia alni (strain ACN14a)
Length = 3139
Score = 37.1 bits (82), Expect = 0.31
Identities = 15/38 (39%), Positives = 27/38 (71%)
Frame = +1
Query: 193 TVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSN 306
T++ C+S + ++ LAAQ L++G D+ LAGG+ M++
Sbjct: 2163 TIDTACSSSLVALHLAAQALRSGETDLALAGGVALMAS 2200
Score = 33.1 bits (72), Expect = 5.0
Identities = 19/55 (34%), Positives = 32/55 (58%), Gaps = 4/55 (7%)
Frame = +1
Query: 193 TVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSN----VPFYLKRGETSYG 345
TV+ C+S + ++ LAAQ L+ G D+ +A G+ M++ V F +RG + G
Sbjct: 200 TVDTACSSALVALHLAAQALRGGETDLAVASGVTVMASPAAFVEFSRQRGLAADG 254
>UniRef50_Q0LKI5 Cluster: Beta-ketoacyl synthase; n=1; Herpetosiphon
aurantiacus ATCC 23779|Rep: Beta-ketoacyl synthase -
Herpetosiphon aurantiacus ATCC 23779
Length = 1939
Score = 37.1 bits (82), Expect = 0.31
Identities = 20/55 (36%), Positives = 32/55 (58%), Gaps = 4/55 (7%)
Frame = +1
Query: 196 VNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVP----FYLKRGETSYGG 348
+N C+ + +I +A Q LQTG D+++AGG+ + S +P F+ K G S G
Sbjct: 276 INTACSGSLVAIHMACQALQTGEADLVVAGGVNA-SLLPDGNLFFSKAGALSPDG 329
>UniRef50_A4KCE4 Cluster: Tautomycetin biosynthetic PKS; n=2; cellular
organisms|Rep: Tautomycetin biosynthetic PKS -
Streptomyces sp. CK4412
Length = 9648
Score = 37.1 bits (82), Expect = 0.31
Identities = 20/73 (27%), Positives = 39/73 (53%)
Frame = +1
Query: 106 GNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAG 285
G++ + G + + GL + +V+ C+S + ++ LAAQ L+TG ++ LAG
Sbjct: 1214 GHLLTGGAGSVISGRVAYALGLEGPAV--SVDTACSSSLVAMHLAAQALRTGECNLALAG 1271
Query: 286 GMESMSNVPFYLK 324
G+ M+ +L+
Sbjct: 1272 GVTVMATPEMFLE 1284
Score = 37.1 bits (82), Expect = 0.31
Identities = 23/82 (28%), Positives = 43/82 (52%)
Frame = +1
Query: 106 GNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAG 285
G++ + G + + GL + +V+ C+S + ++ LAAQ L++G + LAG
Sbjct: 4398 GHLITGGAGSVISGRVAYALGLEGPAV--SVDTACSSSLVAMHLAAQALRSGECSLALAG 4455
Query: 286 GMESMSNVPFYLKRGETSYGGM 351
G+ MS ++ G T+ GG+
Sbjct: 4456 GVMVMSTPDAFV--GFTAQGGL 4475
Score = 35.9 bits (79), Expect = 0.72
Identities = 20/58 (34%), Positives = 34/58 (58%)
Frame = +1
Query: 193 TVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPFYLKRGETSYGGMQLVDG 366
+V+ C+S + ++ LAAQ L++G + LAGG+ M+ ++ G T GG+ DG
Sbjct: 7750 SVDTACSSSLVAMHLAAQALRSGECSLALAGGVTVMATSDMFV--GLTKQGGLS-ADG 7804
Score = 35.5 bits (78), Expect = 0.95
Identities = 18/53 (33%), Positives = 32/53 (60%)
Frame = +1
Query: 193 TVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPFYLKRGETSYGGM 351
+V+ C+S + ++ LAAQ L+ G + LAGG+ M+ ++ G T+ GG+
Sbjct: 2924 SVDTACSSSLVAMHLAAQALRAGECSLALAGGVTVMATADAFV--GFTAQGGL 2974
>UniRef50_A3K5J3 Cluster: Acetyl-CoA acetyltransferase; n=1;
Sagittula stellata E-37|Rep: Acetyl-CoA
acetyltransferase - Sagittula stellata E-37
Length = 408
Score = 37.1 bits (82), Expect = 0.31
Identities = 23/90 (25%), Positives = 40/90 (44%)
Frame = +1
Query: 73 IPKXXIKXVYIGNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGL 252
+P I V + S G A + V LP + T+ C +GM+++ L +
Sbjct: 27 VPGEAIGMVLVATAPSEVEGDL-ARETVQRLDLPATCQTFTLRDTCGAGMQALNLGLCMV 85
Query: 253 QTGAQDIILAGGMESMSNVPFYLKRGETSY 342
+ G QD++L GG + S P + +S+
Sbjct: 86 REGQQDVVLVGGADVPSRAPMVYRSEASSW 115
>UniRef50_A1YAM7 Cluster: Polyketide synthase type I; n=3;
Actinomycetales|Rep: Polyketide synthase type I -
Amycolatopsis orientalis
Length = 5723
Score = 37.1 bits (82), Expect = 0.31
Identities = 30/97 (30%), Positives = 47/97 (48%), Gaps = 4/97 (4%)
Frame = +1
Query: 67 AGIPKXXIKXVYIGNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQ 246
AG P ++ Y+GN A++ GL + TV+ C+S + ++ LAAQ
Sbjct: 170 AGTPPADLEP-YLGNGSFASIASGRVSYTF---GLEGPAV--TVDTACSSSLVALHLAAQ 223
Query: 247 GLQTGAQDIILAGGMESMSN----VPFYLKRGETSYG 345
L+ G + LAGG+ M+N V F +RG + G
Sbjct: 224 ALRQGECSLALAGGVTVMANPAAFVDFSRQRGLAADG 260
Score = 33.5 bits (73), Expect = 3.8
Identities = 20/55 (36%), Positives = 31/55 (56%), Gaps = 4/55 (7%)
Frame = +1
Query: 193 TVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSN----VPFYLKRGETSYG 345
TV+ C+S + ++ LAAQ L+ G + LAGG+ M+ V F +RG + G
Sbjct: 3795 TVDTACSSSLVALHLAAQALRQGECSLALAGGVTVMATPGTFVEFSRQRGLAADG 3849
Score = 33.1 bits (72), Expect = 5.0
Identities = 15/37 (40%), Positives = 24/37 (64%)
Frame = +1
Query: 193 TVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMS 303
TV+ C+S + ++ LAAQ L+ G + LAGG+ M+
Sbjct: 1824 TVDTACSSSLVALHLAAQALRRGECSLALAGGVTVMA 1860
>UniRef50_A1AMI5 Cluster: Beta-ketoacyl synthase; n=1; Pelobacter
propionicus DSM 2379|Rep: Beta-ketoacyl synthase -
Pelobacter propionicus (strain DSM 2379)
Length = 392
Score = 37.1 bits (82), Expect = 0.31
Identities = 16/47 (34%), Positives = 30/47 (63%)
Frame = +1
Query: 175 KSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPF 315
+ + T VN C+SG +I +A L+ G D+++AGG + +++VP+
Sbjct: 142 RGPVLTVVN-ACSSGSDAIGVALSWLKGGLCDLVIAGGADELNHVPY 187
>UniRef50_A0ACH1 Cluster: Putative polyketide synthase B; n=5;
Bacteria|Rep: Putative polyketide synthase B -
Streptomyces ambofaciens ATCC 23877
Length = 8154
Score = 37.1 bits (82), Expect = 0.31
Identities = 17/37 (45%), Positives = 25/37 (67%)
Frame = +1
Query: 193 TVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMS 303
TV+ C+S + ++ LAAQ L+ G D+ LAGG+ MS
Sbjct: 6749 TVDTACSSSLVALHLAAQALRRGECDLALAGGVSVMS 6785
Score = 32.7 bits (71), Expect = 6.7
Identities = 15/37 (40%), Positives = 23/37 (62%)
Frame = +1
Query: 193 TVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMS 303
TV+ C+S + ++ LA Q L+ G D LAGG+ M+
Sbjct: 1705 TVDTACSSSLVAVHLAVQALRNGECDRALAGGVTVMA 1741
>UniRef50_Q9ALM2 Cluster: Polyketide synthase extender modules 8-10;
n=4; Actinomycetales|Rep: Polyketide synthase extender
modules 8-10 - Saccharopolyspora spinosa
Length = 5588
Score = 36.7 bits (81), Expect = 0.41
Identities = 20/66 (30%), Positives = 33/66 (50%)
Frame = +1
Query: 106 GNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAG 285
G + N G + + GL + TV+ C+S + ++ LA Q L+ G D+ LAG
Sbjct: 174 GYFATGNAGSVASGRVAYTFGLEGPAV--TVDTACSSSLVALHLACQSLRLGECDLALAG 231
Query: 286 GMESMS 303
G+ M+
Sbjct: 232 GISVMA 237
Score = 36.7 bits (81), Expect = 0.41
Identities = 22/68 (32%), Positives = 36/68 (52%)
Frame = +1
Query: 100 YIGNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIIL 279
Y+GN + ++ + F G P TV+ C+S + ++ LA Q L++G D+ L
Sbjct: 3699 YLGNGSAGSVASGRIAYSFGFEG-P----AVTVDTACSSSLVALHLAGQSLRSGECDLAL 3753
Query: 280 AGGMESMS 303
AGG+ MS
Sbjct: 3754 AGGVTVMS 3761
Score = 35.1 bits (77), Expect = 1.3
Identities = 15/44 (34%), Positives = 28/44 (63%)
Frame = +1
Query: 193 TVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPFYLK 324
TV+ C+S + ++ LA Q L++G D+ LAGG+ M+ +++
Sbjct: 1950 TVDTACSSSLVALHLAGQALRSGECDLALAGGVTVMATPGMFVE 1993
>UniRef50_Q83WE8 Cluster: Protomycinolide IV synthase 3; n=2;
Micromonospora griseorubida|Rep: Protomycinolide IV
synthase 3 - Micromonospora griseorubida
Length = 3649
Score = 36.7 bits (81), Expect = 0.41
Identities = 21/58 (36%), Positives = 33/58 (56%)
Frame = +1
Query: 193 TVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPFYLKRGETSYGGMQLVDG 366
TV+ C+S + ++ LA Q L++G D+ LAGG+ M+ ++ E S G VDG
Sbjct: 202 TVDTACSSSLVALHLAVQALRSGECDVALAGGVTVMATPGIFV---EFSRQGGLAVDG 256
Score = 32.3 bits (70), Expect = 8.8
Identities = 14/37 (37%), Positives = 23/37 (62%)
Frame = +1
Query: 193 TVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMS 303
TV+ C+S + ++ LA Q L++G D+ L GG M+
Sbjct: 1666 TVDTACSSSLVALHLAVQALRSGECDLALVGGATVMA 1702
>UniRef50_O30764 Cluster: Polyketide synthase modules 1 and 2; n=2;
Streptomyces caelestis|Rep: Polyketide synthase modules 1
and 2 - Streptomyces caelestis
Length = 4340
Score = 36.7 bits (81), Expect = 0.41
Identities = 21/75 (28%), Positives = 37/75 (49%)
Frame = +1
Query: 100 YIGNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIIL 279
Y G++ + L + + GL + TV+ C+S + ++ LA Q L+ G D+ L
Sbjct: 2605 YGGHLLTGTLASVMSGRVAYTLGLQGPAL--TVDTACSSSLVALHLAVQSLRRGECDLAL 2662
Query: 280 AGGMESMSNVPFYLK 324
AGG MS +++
Sbjct: 2663 AGGSTVMSTPTVFVE 2677
Score = 34.7 bits (76), Expect = 1.7
Identities = 16/44 (36%), Positives = 26/44 (59%)
Frame = +1
Query: 193 TVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPFYLK 324
TV+ C+S + ++ LA Q L+ G D+ LAGG MS +++
Sbjct: 1174 TVDTACSSSLVALHLAVQSLRRGECDLALAGGTTVMSGPGMFVE 1217
>UniRef50_A1GD41 Cluster: Acyl transferase region; n=1; Salinispora
arenicola CNS205|Rep: Acyl transferase region -
Salinispora arenicola CNS205
Length = 3508
Score = 36.7 bits (81), Expect = 0.41
Identities = 21/58 (36%), Positives = 33/58 (56%)
Frame = +1
Query: 193 TVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPFYLKRGETSYGGMQLVDG 366
TV+ C+S + S+ LA Q L+ G + LAGG+ M+ +L E+S G+ +DG
Sbjct: 194 TVDTACSSSLVSLHLAVQSLRRGECSMALAGGVALMATPAMFL---ESSGQGVLALDG 248
>UniRef50_Q9S0R3 Cluster: Type I polyketide synthase AVES 4; n=2;
Streptomyces|Rep: Type I polyketide synthase AVES 4 -
Streptomyces avermitilis
Length = 4881
Score = 36.3 bits (80), Expect = 0.54
Identities = 22/75 (29%), Positives = 36/75 (48%)
Frame = +1
Query: 100 YIGNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIIL 279
Y+GN N G + + G + TV+ C+S + ++ LA Q L+TG L
Sbjct: 175 YLGN---GNAGSILSGRVAYTFGFEGPAV--TVDTACSSSLVALHLACQSLRTGESSFAL 229
Query: 280 AGGMESMSNVPFYLK 324
AGG+ MS +++
Sbjct: 230 AGGVTVMSTPGMFVE 244
Score = 33.5 bits (73), Expect = 3.8
Identities = 15/37 (40%), Positives = 24/37 (64%)
Frame = +1
Query: 193 TVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMS 303
TV+ C+S + ++ LA Q L++G + LAGG+ MS
Sbjct: 1758 TVDTACSSSLVALHLACQALRSGECSLALAGGVTVMS 1794
Score = 33.5 bits (73), Expect = 3.8
Identities = 15/37 (40%), Positives = 24/37 (64%)
Frame = +1
Query: 193 TVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMS 303
TV+ C+S + ++ LA Q L++G + LAGG+ MS
Sbjct: 2803 TVDTACSSSLVALHLACQALRSGECSLALAGGVTVMS 2839
>UniRef50_Q2N3S8 Cluster: Polyketide synthase; n=2; Bacteria|Rep:
Polyketide synthase - Polyangium cellulosum (Sorangium
cellulosum)
Length = 4839
Score = 36.3 bits (80), Expect = 0.54
Identities = 17/47 (36%), Positives = 30/47 (63%)
Frame = +1
Query: 193 TVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPFYLKRGE 333
T+N C+S + +I +A Q L +G D++LAGG+ M++ F+ G+
Sbjct: 2941 TINGACSSSLIAIHMACQALWSGEVDLMLAGGVCLMTSHHFHEVAGK 2987
>UniRef50_Q1K1L4 Cluster: Beta-hydroxyacyl-(Acyl-carrier-protein)
dehydratase, FabA/FabZ; n=1; Desulfuromonas acetoxidans
DSM 684|Rep: Beta-hydroxyacyl-(Acyl-carrier-protein)
dehydratase, FabA/FabZ - Desulfuromonas acetoxidans DSM
684
Length = 2241
Score = 36.3 bits (80), Expect = 0.54
Identities = 18/47 (38%), Positives = 26/47 (55%)
Frame = +1
Query: 151 AVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGM 291
AV+ L C T++ CAS + +I LA LQ+G D +L GG+
Sbjct: 176 AVLGKALGLGGTCFTLDAACASSLYAIKLAVDELQSGRADAMLTGGV 222
>UniRef50_Q09DD3 Cluster: MxaC; n=1; Stigmatella aurantiaca
DW4/3-1|Rep: MxaC - Stigmatella aurantiaca DW4/3-1
Length = 1392
Score = 36.3 bits (80), Expect = 0.54
Identities = 21/67 (31%), Positives = 34/67 (50%)
Frame = +1
Query: 196 VNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPFYLKRGETSYGGMQLVDGIVF 375
V CAS + ++ +A+ L++G D++LAGGM + V + S+GG+ F
Sbjct: 690 VESACASSLAALEIASNQLRSGQCDMMLAGGMYASLGVDALSQC--CSFGGLSQNGSFPF 747
Query: 376 DGLTDVY 396
D D Y
Sbjct: 748 DARADGY 754
>UniRef50_A3R4R6 Cluster: Polyketide synthase; n=1; Streptomyces
vitaminophilus|Rep: Polyketide synthase - Streptomyces
vitaminophilus
Length = 2167
Score = 36.3 bits (80), Expect = 0.54
Identities = 24/71 (33%), Positives = 33/71 (46%), Gaps = 2/71 (2%)
Frame = +1
Query: 196 VNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPFYLKRGETSYGGMQLVDG--I 369
V+ C+S + +I LA Q L+ G D+ +AGG MS +L S G DG
Sbjct: 1316 VDTACSSSLTAIHLACQSLRAGESDLAVAGGANVMSTPTVFL---AMSAAGALAPDGRCK 1372
Query: 370 VFDGLTDVYNK 402
FD D Y +
Sbjct: 1373 TFDDSADGYGR 1383
Score = 32.3 bits (70), Expect = 8.8
Identities = 14/36 (38%), Positives = 22/36 (61%)
Frame = +1
Query: 193 TVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESM 300
TVN C+S + ++ LA Q L+ D LAGG+ ++
Sbjct: 194 TVNTACSSSLVAVHLACQSLRNHEVDTALAGGVNAI 229
>UniRef50_A1GGE4 Cluster: Beta-ketoacyl synthase; n=1; Salinispora
arenicola CNS205|Rep: Beta-ketoacyl synthase -
Salinispora arenicola CNS205
Length = 5067
Score = 36.3 bits (80), Expect = 0.54
Identities = 21/66 (31%), Positives = 33/66 (50%)
Frame = +1
Query: 106 GNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAG 285
G + + N G + + G + TV+ C+S + S+ LAAQ L+ G + LAG
Sbjct: 2806 GYLLTGNTGSVASGRVSYTYGFEGPAV--TVDTACSSSLVSLHLAAQALRAGECSLALAG 2863
Query: 286 GMESMS 303
G+ MS
Sbjct: 2864 GVTVMS 2869
Score = 32.3 bits (70), Expect = 8.8
Identities = 19/55 (34%), Positives = 31/55 (56%), Gaps = 4/55 (7%)
Frame = +1
Query: 193 TVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSN----VPFYLKRGETSYG 345
TV+ C+S + ++ LA Q L+ G + LAGG+ M+ V F +RG ++ G
Sbjct: 4553 TVDTACSSSLVALHLAVQSLRQGECSLALAGGVTVMATPGLFVEFSRQRGLSADG 4607
>UniRef50_A0W5R6 Cluster: Beta-ketoacyl synthase; n=1; Geobacter
lovleyi SZ|Rep: Beta-ketoacyl synthase - Geobacter
lovleyi SZ
Length = 2249
Score = 36.3 bits (80), Expect = 0.54
Identities = 14/41 (34%), Positives = 26/41 (63%)
Frame = +1
Query: 196 VNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPFY 318
V+ CAS ++ LA L TGA D+++ GG+++ +++ Y
Sbjct: 212 VDAACASSFSALHLAGMELTTGAADMVVTGGVDTFNDIFMY 252
>UniRef50_UPI0000EBE312 Cluster: PREDICTED: similar to
Acetyl-Coenzyme A acyltransferase 2 (mitochondrial
3-oxoacyl-Coenzyme A thiolase); n=1; Bos taurus|Rep:
PREDICTED: similar to Acetyl-Coenzyme A acyltransferase
2 (mitochondrial 3-oxoacyl-Coenzyme A thiolase) - Bos
taurus
Length = 502
Score = 35.9 bits (79), Expect = 0.72
Identities = 19/83 (22%), Positives = 33/83 (39%), Gaps = 1/83 (1%)
Frame = +1
Query: 1 GRFSXFXXXXXXXXXXXXXIEXAGIPKXXIKXVYIGNVCSANLGQAPAXQAV-IFAGLPK 177
G F + + + V +GNV ++ + V + G+PK
Sbjct: 270 GLLKDFTPTDMAEFAARAALSAGRVSPETVDSVVVGNVMQSSSDAIYLARHVGLRVGIPK 329
Query: 178 STICTTVNKVCASGMKSIMLAAQ 246
T T+N++C SG +SI+ Q
Sbjct: 330 ETPAITINRLCGSGFQSIVSGCQ 352
>UniRef50_Q3AZP4 Cluster: Putative 3-oxoacyl-(Acyl-carrier-protein)
synthase I; n=4; Synechococcus|Rep: Putative
3-oxoacyl-(Acyl-carrier-protein) synthase I -
Synechococcus sp. (strain CC9902)
Length = 423
Score = 35.9 bits (79), Expect = 0.72
Identities = 22/57 (38%), Positives = 28/57 (49%)
Frame = +1
Query: 136 APAXQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSN 306
APA Q I GL CASG +++MLA L D++LAGG E+ N
Sbjct: 143 APAGQVAIDLGLHGGAHAPV--SACASGAEAMMLAQMLLNDDRADLVLAGGTEAPVN 197
>UniRef50_Q2J8Q4 Cluster: Beta-ketoacyl synthase; n=1; Frankia sp.
CcI3|Rep: Beta-ketoacyl synthase - Frankia sp. (strain
CcI3)
Length = 2081
Score = 35.9 bits (79), Expect = 0.72
Identities = 21/55 (38%), Positives = 30/55 (54%), Gaps = 4/55 (7%)
Frame = +1
Query: 193 TVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSN----VPFYLKRGETSYG 345
T++ C+S + ++ LA L+ G D+ LAGG+ MS V F KRG S G
Sbjct: 318 TIDTQCSSSLVAVHLAGHALRAGECDLALAGGVTVMSTPGILVEFSRKRGLASDG 372
>UniRef50_Q93NW6 Cluster: AmphC; n=1; Streptomyces nodosus|Rep: AmphC
- Streptomyces nodosus
Length = 10917
Score = 35.9 bits (79), Expect = 0.72
Identities = 22/55 (40%), Positives = 31/55 (56%), Gaps = 4/55 (7%)
Frame = +1
Query: 193 TVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSN----VPFYLKRGETSYG 345
TV+ C+S + + LAAQ L+TG + LAGG+ MS V F +RG + G
Sbjct: 1927 TVDTACSSSLVGMHLAAQALRTGECTLALAGGVTVMSTPSTFVDFSRQRGLAADG 1981
Score = 34.7 bits (76), Expect = 1.7
Identities = 16/37 (43%), Positives = 25/37 (67%)
Frame = +1
Query: 193 TVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMS 303
TV+ C+S + ++ LAAQ L+TG + LAGG+ +S
Sbjct: 9248 TVDTACSSSLVAMHLAAQALRTGECSLALAGGVTVIS 9284
Score = 34.3 bits (75), Expect = 2.2
Identities = 15/37 (40%), Positives = 25/37 (67%)
Frame = +1
Query: 193 TVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMS 303
T++ C+S + ++ LAAQ L++G + LAGG+ MS
Sbjct: 5740 TIDTACSSALVAMHLAAQALRSGECSLALAGGVTVMS 5776
Score = 33.1 bits (72), Expect = 5.0
Identities = 15/44 (34%), Positives = 27/44 (61%)
Frame = +1
Query: 193 TVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPFYLK 324
TV+ C+S + ++ AAQ L++G + LAGG+ MS +++
Sbjct: 3666 TVDTACSSSLVALHWAAQALRSGECSLALAGGVTVMSTPSTFIE 3709
Score = 32.3 bits (70), Expect = 8.8
Identities = 16/37 (43%), Positives = 23/37 (62%)
Frame = +1
Query: 193 TVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMS 303
TV+ C+S + S+ LAAQ L+ G + LAGG M+
Sbjct: 199 TVDTGCSSSLVSLHLAAQALRGGECSLALAGGASVMA 235
>UniRef50_Q8RL72 Cluster: MmpIV; n=3; cellular organisms|Rep: MmpIV -
Pseudomonas fluorescens
Length = 6521
Score = 35.9 bits (79), Expect = 0.72
Identities = 18/49 (36%), Positives = 25/49 (51%)
Frame = +1
Query: 193 TVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPFYLKRGETS 339
TV+ C+S + +I +A Q L G + LAGG+ S FY K S
Sbjct: 2029 TVDTACSSALVAIHMACQSLLAGDTKVALAGGVFIQSTPAFYQKANRAS 2077
Score = 35.5 bits (78), Expect = 0.95
Identities = 16/53 (30%), Positives = 31/53 (58%)
Frame = +1
Query: 196 VNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPFYLKRGETSYGGMQ 354
V+ +C++ + +I LA QG+++G D+ LAGG+ + YL + ++ Q
Sbjct: 3548 VDSMCSASLTAIHLACQGIRSGDCDVALAGGVNVSVHPNKYLGLAQGNFASSQ 3600
>UniRef50_Q846X3 Cluster: Monensin polyketide synthase modules 5 and
6; n=2; cellular organisms|Rep: Monensin polyketide
synthase modules 5 and 6 - Streptomyces cinnamonensis
Length = 4038
Score = 35.9 bits (79), Expect = 0.72
Identities = 17/37 (45%), Positives = 25/37 (67%)
Frame = +1
Query: 193 TVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMS 303
+V+ C+S + S+ LAAQ L+ G D+ LAGG+ MS
Sbjct: 225 SVDTACSSSLVSMHLAAQALRQGECDLALAGGVTVMS 261
Score = 35.9 bits (79), Expect = 0.72
Identities = 17/38 (44%), Positives = 25/38 (65%)
Frame = +1
Query: 193 TVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSN 306
TV+ C+S + SI LA Q L+ G D+ LAGG+ M++
Sbjct: 2000 TVDTACSSSLVSIHLATQALRHGECDLALAGGVTVMAD 2037
>UniRef50_Q846W6 Cluster: Monensin polyketide synthase modules 11
and 12; n=2; Streptomyces|Rep: Monensin polyketide
synthase modules 11 and 12 - Streptomyces cinnamonensis
Length = 3753
Score = 35.9 bits (79), Expect = 0.72
Identities = 21/66 (31%), Positives = 34/66 (51%)
Frame = +1
Query: 106 GNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAG 285
G + + NLG + + GL + TV+ C+S + +I LA+Q L+ G + LAG
Sbjct: 172 GYIGTGNLGSVVSGRISYTVGLEGPAV--TVDTACSSSLVAIHLASQALRQGECSLALAG 229
Query: 286 GMESMS 303
G M+
Sbjct: 230 GSTVMA 235
Score = 32.3 bits (70), Expect = 8.8
Identities = 25/79 (31%), Positives = 38/79 (48%), Gaps = 4/79 (5%)
Frame = +1
Query: 106 GNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAG 285
G + + NLG + + GL + T++ C+S + +I AA L+ G + LAG
Sbjct: 1722 GYIGTGNLGCVASGRVSYVLGLEGPAM--TIDTGCSSSLVAIHQAAHALRQGECSLALAG 1779
Query: 286 GMESM----SNVPFYLKRG 330
G M S V F L+RG
Sbjct: 1780 GATVMATPGSFVEFSLQRG 1798
>UniRef50_Q76KY0 Cluster: Polyketide synthase modules 1-3; n=2;
cellular organisms|Rep: Polyketide synthase modules 1-3 -
Streptomyces halstedii
Length = 5826
Score = 35.9 bits (79), Expect = 0.72
Identities = 27/86 (31%), Positives = 41/86 (47%), Gaps = 4/86 (4%)
Frame = +1
Query: 100 YIGNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIIL 279
Y+GN + ++ F G P TV+ C+S + ++ AAQ L+ G + L
Sbjct: 4108 YLGNGSAGSIASGRVSYTFGFEG-P----AVTVDTACSSSLVALHWAAQALRQGECSMAL 4162
Query: 280 AGGMESMSN----VPFYLKRGETSYG 345
AGG+ MS V F L+RG + G
Sbjct: 4163 AGGVTVMSTPETFVDFSLQRGLATNG 4188
Score = 33.9 bits (74), Expect = 2.9
Identities = 23/79 (29%), Positives = 38/79 (48%), Gaps = 4/79 (5%)
Frame = +1
Query: 106 GNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAG 285
G + + LG + + GL + T++ C+S + ++ AA L+ G + LAG
Sbjct: 2360 GYIANGTLGSIVSGRVSYALGLEGPAV--TIDTACSSSLVAMHWAAHALRQGECSLALAG 2417
Query: 286 GMESMSN----VPFYLKRG 330
G+ MS V F L+RG
Sbjct: 2418 GVTVMSTPETFVDFSLQRG 2436
>UniRef50_Q6VT93 Cluster: Mixed type I polyketide synthase-peptide
synthetase; n=2; root|Rep: Mixed type I polyketide
synthase-peptide synthetase - symbiont bacterium of
Paederus fuscipes
Length = 6266
Score = 35.9 bits (79), Expect = 0.72
Identities = 15/33 (45%), Positives = 24/33 (72%)
Frame = +1
Query: 193 TVNKVCASGMKSIMLAAQGLQTGAQDIILAGGM 291
TV+ +C+S + ++ LA Q L+TG D+ LAGG+
Sbjct: 3145 TVDTMCSSSLTALHLACQDLKTGRTDMALAGGV 3177
>UniRef50_Q6GVP0 Cluster: Possible polyketide synthase; n=15;
Actinomycetales|Rep: Possible polyketide synthase -
Mycobacterium avium
Length = 2124
Score = 35.9 bits (79), Expect = 0.72
Identities = 15/44 (34%), Positives = 29/44 (65%)
Frame = +1
Query: 193 TVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPFYLK 324
+V+ C+S + ++ LAAQ L++G D+ LAGG+ M+ +++
Sbjct: 201 SVDTACSSSLVALHLAAQSLRSGECDLALAGGVTVMATPAMFIE 244
>UniRef50_Q3VXM8 Cluster: Beta-ketoacyl synthase:Acyl transferase
domain:Phosphopantetheine- binding domain; n=1; Frankia
sp. EAN1pec|Rep: Beta-ketoacyl synthase:Acyl transferase
domain:Phosphopantetheine- binding domain - Frankia sp.
EAN1pec
Length = 1240
Score = 35.9 bits (79), Expect = 0.72
Identities = 15/43 (34%), Positives = 27/43 (62%)
Frame = +1
Query: 193 TVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPFYL 321
TV+ C+S + ++ LA Q L+ G D+ LAGG +++N ++
Sbjct: 274 TVDTACSSSLVALHLAVQSLRRGECDLALAGGATTLANPDIFV 316
>UniRef50_Q1Q275 Cluster: Similar to beta-ketoacyl (Acyl carrier
protein ) synthase II; n=1; Candidatus Kuenenia
stuttgartiensis|Rep: Similar to beta-ketoacyl (Acyl
carrier protein ) synthase II - Candidatus Kuenenia
stuttgartiensis
Length = 393
Score = 35.9 bits (79), Expect = 0.72
Identities = 15/38 (39%), Positives = 26/38 (68%)
Frame = +1
Query: 193 TVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSN 306
TV+ C SG +I +AA+ + +G DI++AGG + +S+
Sbjct: 147 TVSTACTSGTDAIGIAARSILSGKTDIMIAGGADILSD 184
>UniRef50_Q0VZ73 Cluster: Polyketide synthase; n=1; Chondromyces
crocatus|Rep: Polyketide synthase - Chondromyces crocatus
Length = 4182
Score = 35.9 bits (79), Expect = 0.72
Identities = 15/35 (42%), Positives = 23/35 (65%)
Frame = +1
Query: 187 CTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGM 291
C V+ C+S + +I LA Q L++G D+ LAGG+
Sbjct: 2476 CVAVDTACSSSLVAISLACQSLRSGDCDLALAGGV 2510
>UniRef50_Q0RLH1 Cluster: Putative polyketide synthase; n=1; Frankia
alni ACN14a|Rep: Putative polyketide synthase - Frankia
alni (strain ACN14a)
Length = 2295
Score = 35.9 bits (79), Expect = 0.72
Identities = 15/38 (39%), Positives = 24/38 (63%)
Frame = +1
Query: 187 CTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESM 300
C TV+ C+S + ++ LA+Q L+ G + LAGG+ M
Sbjct: 204 CLTVDTACSSSLVAVHLASQSLRAGECSVALAGGVTLM 241
>UniRef50_P95814 Cluster: FK506 polyketide synthase; n=2;
Streptomyces|Rep: FK506 polyketide synthase -
Streptomyces sp
Length = 6420
Score = 35.9 bits (79), Expect = 0.72
Identities = 20/55 (36%), Positives = 33/55 (60%), Gaps = 4/55 (7%)
Frame = +1
Query: 193 TVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSN----VPFYLKRGETSYG 345
TV+ C+S + ++ LA QGL+ G ++ LAGG+ +S+ V F +RG + G
Sbjct: 5573 TVDTACSSSLVALHLACQGLRLGECELALAGGVSVLSSPAAFVEFSRQRGLAADG 5627
>UniRef50_A6PQN7 Cluster: Beta-ketoacyl synthase precursor; n=1;
Victivallis vadensis ATCC BAA-548|Rep: Beta-ketoacyl
synthase precursor - Victivallis vadensis ATCC BAA-548
Length = 408
Score = 35.9 bits (79), Expect = 0.72
Identities = 14/29 (48%), Positives = 22/29 (75%)
Frame = +1
Query: 208 CASGMKSIMLAAQGLQTGAQDIILAGGME 294
CASG++S+ A + +Q G QD++LAGG +
Sbjct: 165 CASGLQSVGAAMEQIQLGKQDVMLAGGSD 193
>UniRef50_A6GK65 Cluster: Polyketide synthase type I; n=2;
Plesiocystis pacifica SIR-1|Rep: Polyketide synthase
type I - Plesiocystis pacifica SIR-1
Length = 3091
Score = 35.9 bits (79), Expect = 0.72
Identities = 15/35 (42%), Positives = 21/35 (60%)
Frame = +1
Query: 187 CTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGM 291
C VN C+S + ++ LA Q L+ G I LAGG+
Sbjct: 221 CMVVNTACSSALVAVHLACQALRLGESQIALAGGV 255
>UniRef50_A6G4P0 Cluster: Putative multi-domain beta keto-acyl
synthase; n=1; Plesiocystis pacifica SIR-1|Rep: Putative
multi-domain beta keto-acyl synthase - Plesiocystis
pacifica SIR-1
Length = 1179
Score = 35.9 bits (79), Expect = 0.72
Identities = 12/47 (25%), Positives = 32/47 (68%)
Frame = +1
Query: 196 VNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPFYLKRGET 336
++ CAS + ++ +A LQ G D++++GG+++++++ ++ G+T
Sbjct: 210 LDAACASSLAAVEMAVLELQAGRADMVISGGVDALNDIFMHMCFGQT 256
>UniRef50_A4FCY9 Cluster: Modular polyketide synthase; n=3; cellular
organisms|Rep: Modular polyketide synthase -
Saccharopolyspora erythraea (strain NRRL 23338)
Length = 4576
Score = 35.9 bits (79), Expect = 0.72
Identities = 16/46 (34%), Positives = 29/46 (63%)
Frame = +1
Query: 193 TVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPFYLKRG 330
TV+ C+S + ++ LA + L+ G ++ LAGG+ MSN +++ G
Sbjct: 1182 TVDTACSSSLVALHLAVEALRHGECELALAGGVTVMSNPGIFVEFG 1227
Score = 35.9 bits (79), Expect = 0.72
Identities = 17/38 (44%), Positives = 25/38 (65%)
Frame = +1
Query: 193 TVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSN 306
TV+ C+S + ++ LAAQ LQ G + LAGG+ MS+
Sbjct: 2962 TVDTACSSSLVALHLAAQSLQRGECGLALAGGVTVMSS 2999
>UniRef50_A0VU10 Cluster: Beta-ketoacyl synthase; n=1; Dinoroseobacter
shibae DFL 12|Rep: Beta-ketoacyl synthase -
Dinoroseobacter shibae DFL 12
Length = 2576
Score = 35.9 bits (79), Expect = 0.72
Identities = 14/41 (34%), Positives = 26/41 (63%)
Frame = +1
Query: 193 TVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPF 315
TV+ C S + ++M+A++ L+ D+++ GG +S N PF
Sbjct: 903 TVDAACGSSLAAVMMASRELENHTSDMVIVGGADSFQN-PF 942
>UniRef50_Q6RKI7 Cluster: Polyketide synthase; n=3;
Sclerotiniaceae|Rep: Polyketide synthase - Botrytis
cinerea (Noble rot fungus) (Botryotinia fuckeliana)
Length = 2126
Score = 35.9 bits (79), Expect = 0.72
Identities = 18/49 (36%), Positives = 28/49 (57%), Gaps = 2/49 (4%)
Frame = +1
Query: 193 TVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPFY--LKRGE 333
+V+ C+S M +I LA L+ G D + AGGM M+N + L +G+
Sbjct: 539 SVDTACSSSMAAINLAVTSLRAGDCDTVFAGGMNVMTNPDIFSGLSKGQ 587
>UniRef50_Q07017 Cluster: Oleandomycin polyketide synthase, modules
5 and 6; n=1; Streptomyces antibioticus|Rep:
Oleandomycin polyketide synthase, modules 5 and 6 -
Streptomyces antibioticus
Length = 3519
Score = 35.9 bits (79), Expect = 0.72
Identities = 25/80 (31%), Positives = 38/80 (47%)
Frame = +1
Query: 67 AGIPKXXIKXVYIGNVCSANLGQAPAXQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQ 246
AG P ++ + LG A A F GL + TV+ C+S + ++ LA Q
Sbjct: 166 AGSPYRLVEGLEGQLAIGTTLGAASGRVAYTF-GLEGPAV--TVDTACSSSLVALHLAVQ 222
Query: 247 GLQTGAQDIILAGGMESMSN 306
GL+ G + L GG+ MS+
Sbjct: 223 GLRRGECSLALVGGVTVMSS 242
>UniRef50_Q93HJ5 Cluster: Modular polyketide synthase; n=5;
Actinomycetales|Rep: Modular polyketide synthase -
Streptomyces avermitilis
Length = 6146
Score = 35.5 bits (78), Expect = 0.95
Identities = 16/37 (43%), Positives = 25/37 (67%)
Frame = +1
Query: 193 TVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMS 303
TV+ C+S + ++ LAAQ L+ G D+ LAGG+ M+
Sbjct: 4147 TVDTACSSSLVALHLAAQALRGGECDVALAGGVAVMA 4183
Score = 35.1 bits (77), Expect = 1.3
Identities = 16/37 (43%), Positives = 25/37 (67%)
Frame = +1
Query: 193 TVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMS 303
TV+ C+S + ++ LAAQ L+ G D+ LAGG+ M+
Sbjct: 1166 TVDTACSSSLVALHLAAQALRGGECDLALAGGVTVMA 1202
>UniRef50_Q9L4X3 Cluster: NysI; n=4; root|Rep: NysI - Streptomyces
noursei
Length = 9477
Score = 35.5 bits (78), Expect = 0.95
Identities = 20/58 (34%), Positives = 32/58 (55%)
Frame = +1
Query: 193 TVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPFYLKRGETSYGGMQLVDG 366
TV+ C+S + ++ LA Q L+ G + LAGG+ MS +++ G GG+ DG
Sbjct: 190 TVDTACSSSLVAVHLATQALRAGECTLALAGGVTIMSGPGTFIEMGR--QGGLS-ADG 244
Score = 33.1 bits (72), Expect = 5.0
Identities = 14/37 (37%), Positives = 23/37 (62%)
Frame = +1
Query: 193 TVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMS 303
T++ C+S + ++ LA Q L+ G + LAGG+ MS
Sbjct: 5067 TLDTACSSSLVAMHLACQSLRNGESSLALAGGVSIMS 5103
Score = 32.7 bits (71), Expect = 6.7
Identities = 15/37 (40%), Positives = 24/37 (64%)
Frame = +1
Query: 193 TVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMS 303
+V+ C+S + ++ LAAQ L+ G I LAGG+ M+
Sbjct: 8067 SVDTACSSSLVALHLAAQALRAGECSIALAGGVTVMA 8103
>UniRef50_Q93HF2 Cluster: Modular polyketide synthase; n=2;
Streptomyces avermitilis|Rep: Modular polyketide
synthase - Streptomyces avermitilis
Length = 1512
Score = 35.5 bits (78), Expect = 0.95
Identities = 26/96 (27%), Positives = 43/96 (44%), Gaps = 2/96 (2%)
Frame = +1
Query: 187 CTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSN--VPFYLKRGETSYGGMQLV 360
C +++ CAS + ++ AA+GL+ G DI LAG + ++ + +P Q
Sbjct: 198 CMSLDTACASSLTALHSAAEGLRRGECDIALAGAVNALHHPRIPVIFSAANMLAPDAQCK 257
Query: 361 DGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQD 468
FD D Y + CA K+L ++D D
Sbjct: 258 ---TFDESADGYVRAE--GCAVAVLKRLSDAQRDGD 288
>UniRef50_Q6W5P6 Cluster: FscD; n=6; Bacteria|Rep: FscD - Streptomyces
sp. FR-008
Length = 9550
Score = 35.5 bits (78), Expect = 0.95
Identities = 16/47 (34%), Positives = 30/47 (63%)
Frame = +1
Query: 193 TVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPFYLKRGE 333
+V+ C+S + ++ LAAQ +++G + LAGG+ MS +++ GE
Sbjct: 8093 SVDTACSSSLTALHLAAQAIRSGECSLALAGGVTVMSTPVGFVEFGE 8139
Score = 35.1 bits (77), Expect = 1.3
Identities = 17/42 (40%), Positives = 26/42 (61%), Gaps = 1/42 (2%)
Frame = +1
Query: 193 TVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSN-VPF 315
TV+ C+S + ++ LA Q L+ G + LAGG M+N +PF
Sbjct: 3507 TVDTACSSSLVALHLACQSLRNGETTLALAGGATVMTNPMPF 3548
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 502,290,533
Number of Sequences: 1657284
Number of extensions: 9634208
Number of successful extensions: 27292
Number of sequences better than 10.0: 450
Number of HSP's better than 10.0 without gapping: 25773
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 27191
length of database: 575,637,011
effective HSP length: 97
effective length of database: 414,880,463
effective search space used: 41488046300
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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