Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P15_F_L19
(671 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AY368150-1|AAR89381.1| 893|Homo sapiens KIAA1228 protein protein. 139 1e-32
DQ993201-1|ABJ97706.1| 921|Homo sapiens extended-synaptotagmin ... 138 2e-32
AB033054-1|BAA86542.2| 843|Homo sapiens KIAA1228 protein protein. 138 2e-32
DQ993202-1|ABJ97707.1| 886|Homo sapiens extended-synaptotagmin ... 137 4e-32
BC037292-1|AAH37292.1| 501|Homo sapiens FAM62C protein protein. 137 4e-32
DQ993200-1|ABJ97705.1| 1104|Homo sapiens extended-synaptotagmin ... 126 7e-29
BC004998-1|AAH04998.1| 1104|Homo sapiens family with sequence si... 126 7e-29
AB018290-1|BAA34467.1| 1072|Homo sapiens KIAA0747 protein protein. 124 4e-28
AK126214-1|BAC86489.1| 527|Homo sapiens protein ( Homo sapiens ... 91 3e-18
AB045125-1|BAD83600.1| 361|Homo sapiens KPG_013 protein protein. 33 1.2
U10554-1|AAB92675.1| 532|Homo sapiens vesicular acetylcholine t... 31 5.0
U09210-1|AAA20497.1| 532|Homo sapiens vesicular acetylcholine t... 31 5.0
BC007765-1|AAH07765.1| 532|Homo sapiens solute carrier family 1... 31 5.0
>AY368150-1|AAR89381.1| 893|Homo sapiens KIAA1228 protein protein.
Length = 893
Score = 139 bits (336), Expect = 1e-32
Identities = 80/228 (35%), Positives = 129/228 (56%), Gaps = 9/228 (3%)
Frame = +2
Query: 14 GASKTALP--PGSDDGNSVFSMMYTFLKKVSIVGAVYLVGYMQWSVAWLIGPVILSVMRD 187
GA A P PG + ++ + +++ VY +GY+ S +W V+L++
Sbjct: 63 GAGGRAAPENPGGVLSVELPGLLAQLARSFALLLPVYALGYLGLSFSW----VLLALALL 118
Query: 188 QW-RKENEYK--RNIAKVAALSSEKDVIL--ARLDDLPSWVFFPDVERAEWLNRILLQVW 352
W R+ K R +A L E+ V+ R DLP+WV FPD ERAEWLN+ + +W
Sbjct: 119 AWCRRSRGLKALRLCRALALLEDEERVVRLGVRACDLPAWVHFPDTERAEWLNKTVKHMW 178
Query: 353 PNVNSYAKTLLKDLIEPAVAESLANYKLSGFKFERMILGTIAPRVGGVKVYDKNLSRNEI 532
P + + + L ++ IEPAV AN LS F F ++ +G R+ GVKVY +N+ + +I
Sbjct: 179 PFICQFIEKLFRETIEPAVRG--ANTHLSTFSFTKVDVGQQPLRINGVKVYTENVDKRQI 236
Query: 533 IMDIDLFYAGDCDISFVLQR--IRGGIKDLQIHGMVRVVMKPLISKIP 670
I+D+ + + G+C+I ++R R G+K +QIHG +RV+++PLI +P
Sbjct: 237 ILDLQISFVGNCEIDLEIKRYFCRAGVKSIQIHGTMRVILEPLIGDMP 284
>DQ993201-1|ABJ97706.1| 921|Homo sapiens extended-synaptotagmin 2
protein.
Length = 921
Score = 138 bits (333), Expect = 2e-32
Identities = 80/234 (34%), Positives = 133/234 (56%), Gaps = 15/234 (6%)
Frame = +2
Query: 14 GASKTALPP---GSDDGNSVFS-----MMYTFLKKVSIVGAVYLVGYMQWSVAWLIGPVI 169
G+++ PP G ++ V S ++ + +++ VY +GY+ S +W V+
Sbjct: 85 GSARAPSPPRPGGPENPGGVLSVELPGLLAQLARSFALLLPVYALGYLGLSFSW----VL 140
Query: 170 LSVMRDQW-RKENEYK--RNIAKVAALSSEKDVIL--ARLDDLPSWVFFPDVERAEWLNR 334
L++ W R+ K R +A L E+ V+ R DLP+WV FPD ERAEWLN+
Sbjct: 141 LALALLAWCRRSRGLKALRLCRALALLEDEERVVRLGVRACDLPAWVHFPDTERAEWLNK 200
Query: 335 ILLQVWPNVNSYAKTLLKDLIEPAVAESLANYKLSGFKFERMILGTIAPRVGGVKVYDKN 514
+ +WP + + + L ++ IEPAV AN LS F F ++ +G R+ GVKVY +N
Sbjct: 201 TVKHMWPFICQFIEKLFRETIEPAVRG--ANTHLSTFSFTKVDVGQQPLRINGVKVYTEN 258
Query: 515 LSRNEIIMDIDLFYAGDCDISFVLQR--IRGGIKDLQIHGMVRVVMKPLISKIP 670
+ + +II+D+ + + G+C+I ++R R G+K +QIHG +RV+++PLI +P
Sbjct: 259 VDKRQIILDLQISFVGNCEIDLEIKRYFCRAGVKSIQIHGTMRVILEPLIGDMP 312
>AB033054-1|BAA86542.2| 843|Homo sapiens KIAA1228 protein protein.
Length = 843
Score = 138 bits (333), Expect = 2e-32
Identities = 80/234 (34%), Positives = 133/234 (56%), Gaps = 15/234 (6%)
Frame = +2
Query: 14 GASKTALPP---GSDDGNSVFS-----MMYTFLKKVSIVGAVYLVGYMQWSVAWLIGPVI 169
G+++ PP G ++ V S ++ + +++ VY +GY+ S +W V+
Sbjct: 7 GSARAPSPPRPGGPENPGGVLSVELPGLLAQLARSFALLLPVYALGYLGLSFSW----VL 62
Query: 170 LSVMRDQW-RKENEYK--RNIAKVAALSSEKDVIL--ARLDDLPSWVFFPDVERAEWLNR 334
L++ W R+ K R +A L E+ V+ R DLP+WV FPD ERAEWLN+
Sbjct: 63 LALALLAWCRRSRGLKALRLCRALALLEDEERVVRLGVRACDLPAWVHFPDTERAEWLNK 122
Query: 335 ILLQVWPNVNSYAKTLLKDLIEPAVAESLANYKLSGFKFERMILGTIAPRVGGVKVYDKN 514
+ +WP + + + L ++ IEPAV AN LS F F ++ +G R+ GVKVY +N
Sbjct: 123 TVKHMWPFICQFIEKLFRETIEPAVRG--ANTHLSTFSFTKVDVGQQPLRINGVKVYTEN 180
Query: 515 LSRNEIIMDIDLFYAGDCDISFVLQR--IRGGIKDLQIHGMVRVVMKPLISKIP 670
+ + +II+D+ + + G+C+I ++R R G+K +QIHG +RV+++PLI +P
Sbjct: 181 VDKRQIILDLQISFVGNCEIDLEIKRYFCRAGVKSIQIHGTMRVILEPLIGDMP 234
>DQ993202-1|ABJ97707.1| 886|Homo sapiens extended-synaptotagmin 3
protein.
Length = 886
Score = 137 bits (331), Expect = 4e-32
Identities = 70/202 (34%), Positives = 114/202 (56%), Gaps = 5/202 (2%)
Frame = +2
Query: 80 TFLKKVSI-VGAVYLVGYMQWSVAWLIGPVILSVMRDQWRKENEYK--RNIAKVAALSSE 250
TF+ +V +G VYL GY+ S+ WL+ +L + WR+ K R A L +E
Sbjct: 37 TFVVRVLFYLGPVYLAGYLGLSITWLLLGALLWMW---WRRNRRGKLGRLAAAFEFLDNE 93
Query: 251 KDVILARL--DDLPSWVFFPDVERAEWLNRILLQVWPNVNSYAKTLLKDLIEPAVAESLA 424
++ I L LP+W+ FPDVER EW N+I+ Q WP ++ ++ ++ +EP + E
Sbjct: 94 REFISRELRGQHLPAWIHFPDVERVEWANKIISQTWPYLSMIMESKFREKLEPKIREK-- 151
Query: 425 NYKLSGFKFERMILGTIAPRVGGVKVYDKNLSRNEIIMDIDLFYAGDCDISFVLQRIRGG 604
+ L F F ++ G PRV GVK + +R + +D+ + Y GDC+IS LQ+I+ G
Sbjct: 152 SIHLRTFTFTKLYFGQKCPRVNGVKAHTNTCNRRRVTVDLQICYIGDCEISVELQKIQAG 211
Query: 605 IKDLQIHGMVRVVMKPLISKIP 670
+ +Q+ G +RV+++PL+ P
Sbjct: 212 VNGIQLQGTLRVILEPLLVDKP 233
>BC037292-1|AAH37292.1| 501|Homo sapiens FAM62C protein protein.
Length = 501
Score = 137 bits (331), Expect = 4e-32
Identities = 70/202 (34%), Positives = 114/202 (56%), Gaps = 5/202 (2%)
Frame = +2
Query: 80 TFLKKVSI-VGAVYLVGYMQWSVAWLIGPVILSVMRDQWRKENEYK--RNIAKVAALSSE 250
TF+ +V +G VYL GY+ S+ WL+ +L + WR+ K R A L +E
Sbjct: 37 TFVVRVLFYLGPVYLAGYLGLSITWLLLGALLWMW---WRRNRRGKLGRLAAAFEFLDNE 93
Query: 251 KDVILARL--DDLPSWVFFPDVERAEWLNRILLQVWPNVNSYAKTLLKDLIEPAVAESLA 424
++ I L LP+W+ FPDVER EW N+I+ Q WP ++ ++ ++ +EP + E
Sbjct: 94 REFISRELRGQHLPAWIHFPDVERVEWANKIISQTWPYLSMIMESKFREKLEPKIREK-- 151
Query: 425 NYKLSGFKFERMILGTIAPRVGGVKVYDKNLSRNEIIMDIDLFYAGDCDISFVLQRIRGG 604
+ L F F ++ G PRV GVK + +R + +D+ + Y GDC+IS LQ+I+ G
Sbjct: 152 SIHLRTFTFTKLYFGQKCPRVNGVKAHTNTCNRRRVTVDLQICYIGDCEISVELQKIQAG 211
Query: 605 IKDLQIHGMVRVVMKPLISKIP 670
+ +Q+ G +RV+++PL+ P
Sbjct: 212 VNGIQLQGTLRVILEPLLVDKP 233
>DQ993200-1|ABJ97705.1| 1104|Homo sapiens extended-synaptotagmin 1
protein.
Length = 1104
Score = 126 bits (304), Expect = 7e-29
Identities = 71/220 (32%), Positives = 128/220 (58%), Gaps = 8/220 (3%)
Frame = +2
Query: 35 PPGSDDGNSVFSMMYTFLKKVSIVGAVYLVGYMQWSVAWLIGPVILSVMRDQWRK-ENEY 211
P G +++ +F +++ ++ VYL G + SV +++ + L + WR+ +E
Sbjct: 42 PAGPGAAGEALAVLTSFGRRLLVLIPVYLAGAVGLSVGFVLFGLALYL---GWRRVRDEK 98
Query: 212 KRNIAKVAALSSEKDVILARL-----DDLPSWVFFPDVERAEWLNRILLQVWPNVNSYAK 376
+R++ L +++ + A+ +LP+WV FPDVE+AEWLN+I+ QVWP + Y +
Sbjct: 99 ERSLRAARQLLDDEEQLTAKTLYMSHRELPAWVSFPDVEKAEWLNKIVAQVWPFLGQYME 158
Query: 377 TLLKDLIEPAVAESLANYKLSGFKFERMILGTIAPRVGGVKVYDKNLSRNEIIMDIDLFY 556
LL + + PAV S N L F F R+ LG R+ GVKV+ + +I++D+++ Y
Sbjct: 159 KLLAETVAPAVRGS--NPHLQTFTFTRVELGEKPLRIIGVKVH-PGQRKEQILLDLNISY 215
Query: 557 AGDCDISFVLQR--IRGGIKDLQIHGMVRVVMKPLISKIP 670
GD I +++ + G+K +Q+HG++RV+++PLI +P
Sbjct: 216 VGDVQIDVEVKKYFCKAGVKGMQLHGVLRVILEPLIGDLP 255
>BC004998-1|AAH04998.1| 1104|Homo sapiens family with sequence
similarity 62 (C2 domain containing), member A protein.
Length = 1104
Score = 126 bits (304), Expect = 7e-29
Identities = 71/220 (32%), Positives = 128/220 (58%), Gaps = 8/220 (3%)
Frame = +2
Query: 35 PPGSDDGNSVFSMMYTFLKKVSIVGAVYLVGYMQWSVAWLIGPVILSVMRDQWRK-ENEY 211
P G +++ +F +++ ++ VYL G + SV +++ + L + WR+ +E
Sbjct: 42 PAGPGAAGEALAVLTSFGRRLLVLIPVYLAGAVGLSVGFVLFGLALYL---GWRRVRDEK 98
Query: 212 KRNIAKVAALSSEKDVILARL-----DDLPSWVFFPDVERAEWLNRILLQVWPNVNSYAK 376
+R++ L +++ + A+ +LP+WV FPDVE+AEWLN+I+ QVWP + Y +
Sbjct: 99 ERSLRAARQLLDDEEQLTAKTLYMSHRELPAWVSFPDVEKAEWLNKIVAQVWPFLGQYME 158
Query: 377 TLLKDLIEPAVAESLANYKLSGFKFERMILGTIAPRVGGVKVYDKNLSRNEIIMDIDLFY 556
LL + + PAV S N L F F R+ LG R+ GVKV+ + +I++D+++ Y
Sbjct: 159 KLLAETVAPAVRGS--NPHLQTFTFTRVELGEKPLRIIGVKVH-PGQRKEQILLDLNISY 215
Query: 557 AGDCDISFVLQR--IRGGIKDLQIHGMVRVVMKPLISKIP 670
GD I +++ + G+K +Q+HG++RV+++PLI +P
Sbjct: 216 VGDVQIDVEVKKYFCKAGVKGMQLHGVLRVILEPLIGDLP 255
>AB018290-1|BAA34467.1| 1072|Homo sapiens KIAA0747 protein protein.
Length = 1072
Score = 124 bits (298), Expect = 4e-28
Identities = 70/218 (32%), Positives = 127/218 (58%), Gaps = 8/218 (3%)
Frame = +2
Query: 41 GSDDGNSVFSMMYTFLKKVSIVGAVYLVGYMQWSVAWLIGPVILSVMRDQWRK-ENEYKR 217
G +++ +F +++ ++ VYL G + SV +++ + L + WR+ +E +R
Sbjct: 2 GPGAAGEALAVLTSFGRRLLVLIPVYLAGAVGLSVGFVLFGLALYL---GWRRVRDEKER 58
Query: 218 NIAKVAALSSEKDVILARL-----DDLPSWVFFPDVERAEWLNRILLQVWPNVNSYAKTL 382
++ L +++ + A+ +LP+WV FPDVE+AEWLN+I+ QVWP + Y + L
Sbjct: 59 SLRAARQLLDDEEQLTAKTLYMSHRELPAWVSFPDVEKAEWLNKIVAQVWPFLGQYMEKL 118
Query: 383 LKDLIEPAVAESLANYKLSGFKFERMILGTIAPRVGGVKVYDKNLSRNEIIMDIDLFYAG 562
L + + PAV S N L F F R+ LG R+ GVKV+ + +I++D+++ Y G
Sbjct: 119 LAETVAPAVRGS--NPHLQTFTFTRVELGEKPLRIIGVKVH-PGQRKEQILLDLNISYVG 175
Query: 563 DCDISFVLQR--IRGGIKDLQIHGMVRVVMKPLISKIP 670
D I +++ + G+K +Q+HG++RV+++PLI +P
Sbjct: 176 DVQIDVEVKKYFCKAGVKGMQLHGVLRVILEPLIGDLP 213
>AK126214-1|BAC86489.1| 527|Homo sapiens protein ( Homo sapiens
cDNA FLJ44226 fis, clone THYMU3006172, moderately
similar to Rattus norvegicus membrane bound C2 domain
containing ).
Length = 527
Score = 91.5 bits (217), Expect = 3e-18
Identities = 42/110 (38%), Positives = 71/110 (64%), Gaps = 2/110 (1%)
Frame = +2
Query: 347 VWPNVNSYAKTLLKDLIEPAVAESLANYKLSGFKFERMILGTIAPRVGGVKVYDKNLSRN 526
+WP + + + L ++ IEPAV AN LS F F ++ +G R+ GVKVY +N+ +
Sbjct: 1 MWPFICQFIEKLFRETIEPAVRG--ANTHLSTFSFTKVDVGQQPLRINGVKVYTENVDKR 58
Query: 527 EIIMDIDLFYAGDCDISFVLQR--IRGGIKDLQIHGMVRVVMKPLISKIP 670
+II+D+ + + G+C+I ++R R G+K +QIHG +RV+++PLI +P
Sbjct: 59 QIILDLQISFVGNCEIDLEIKRYFCRAGVKSIQIHGTMRVILEPLIGDMP 108
>AB045125-1|BAD83600.1| 361|Homo sapiens KPG_013 protein protein.
Length = 361
Score = 32.7 bits (71), Expect = 1.2
Identities = 20/74 (27%), Positives = 36/74 (48%)
Frame = +2
Query: 53 GNSVFSMMYTFLKKVSIVGAVYLVGYMQWSVAWLIGPVILSVMRDQWRKENEYKRNIAKV 232
G + ++ F + A+ LV ++W+ AWL+GPV+ ++ I +
Sbjct: 72 GATASLVLNLFCADLLFTSAIPLVLVVRWTEAWLLGPVVCHLLFYVMTMSGSV--TILTL 129
Query: 233 AALSSEKDVILARL 274
AA+S E+ V + RL
Sbjct: 130 AAVSLERMVCIVRL 143
>U10554-1|AAB92675.1| 532|Homo sapiens vesicular acetylcholine
transporter protein.
Length = 532
Score = 30.7 bits (66), Expect = 5.0
Identities = 10/28 (35%), Positives = 21/28 (75%)
Frame = +2
Query: 86 LKKVSIVGAVYLVGYMQWSVAWLIGPVI 169
++ VS+ G+VY + + +SVA+ +GP++
Sbjct: 411 VRHVSVYGSVYAIADISYSVAYALGPIV 438
>U09210-1|AAA20497.1| 532|Homo sapiens vesicular acetylcholine
transporter protein.
Length = 532
Score = 30.7 bits (66), Expect = 5.0
Identities = 10/28 (35%), Positives = 21/28 (75%)
Frame = +2
Query: 86 LKKVSIVGAVYLVGYMQWSVAWLIGPVI 169
++ VS+ G+VY + + +SVA+ +GP++
Sbjct: 411 VRHVSVYGSVYAIADISYSVAYALGPIV 438
>BC007765-1|AAH07765.1| 532|Homo sapiens solute carrier family 18
(vesicular acetylcholine), member 3 protein.
Length = 532
Score = 30.7 bits (66), Expect = 5.0
Identities = 10/28 (35%), Positives = 21/28 (75%)
Frame = +2
Query: 86 LKKVSIVGAVYLVGYMQWSVAWLIGPVI 169
++ VS+ G+VY + + +SVA+ +GP++
Sbjct: 411 VRHVSVYGSVYAIADISYSVAYALGPIV 438
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 97,501,586
Number of Sequences: 237096
Number of extensions: 2060887
Number of successful extensions: 5183
Number of sequences better than 10.0: 13
Number of HSP's better than 10.0 without gapping: 4944
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5152
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 7647512560
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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