Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P15_F_K17
(857 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q9VXQ3 Cluster: CG8239-PA; n=5; Endopterygota|Rep: CG82... 259 7e-68
UniRef50_A7SHV3 Cluster: Predicted protein; n=1; Nematostella ve... 257 2e-67
UniRef50_P53602 Cluster: Diphosphomevalonate decarboxylase (EC 4... 253 4e-66
UniRef50_Q8LAR8 Cluster: Diphosphomevalonate decarboxylase-like ... 248 1e-64
UniRef50_P32377 Cluster: Diphosphomevalonate decarboxylase; n=35... 245 1e-63
UniRef50_Q54YQ9 Cluster: Putative uncharacterized protein; n=1; ... 236 5e-61
UniRef50_Q4P3Y4 Cluster: Putative uncharacterized protein; n=1; ... 223 4e-57
UniRef50_Q4QE40 Cluster: Diphosphomevalonate decarboxylase, puta... 222 1e-56
UniRef50_UPI0000E24443 Cluster: PREDICTED: diphosphomevalonate d... 124 1e-56
UniRef50_Q0E4P1 Cluster: Os02g0107200 protein; n=2; Oryza sativa... 221 2e-56
UniRef50_A3A295 Cluster: Putative uncharacterized protein; n=2; ... 221 2e-56
UniRef50_Q1DZV7 Cluster: Putative uncharacterized protein; n=1; ... 194 2e-48
UniRef50_Q29CM9 Cluster: GA20922-PA; n=1; Drosophila pseudoobscu... 186 6e-46
UniRef50_Q9U294 Cluster: Putative uncharacterized protein; n=3; ... 175 9e-43
UniRef50_Q4J9D9 Cluster: Diphosphomevalonate decarboxylase; n=4;... 138 1e-31
UniRef50_Q1D2F0 Cluster: Diphosphomevalonate decarboxylase; n=2;... 126 9e-28
UniRef50_Q8YAV2 Cluster: Lmo0011 protein; n=18; Bacilli|Rep: Lmo... 125 1e-27
UniRef50_A0CNB5 Cluster: Chromosome undetermined scaffold_22, wh... 119 1e-25
UniRef50_Q9FD68 Cluster: Mevalonate diphosphate decarboxylase; n... 116 8e-25
UniRef50_Q0LPG3 Cluster: Diphosphomevalonate decarboxylase; n=1;... 115 1e-24
UniRef50_A2EGU1 Cluster: Diphosphomevalonate decarboxylase famil... 115 1e-24
UniRef50_Q03FN8 Cluster: Mevalonate pyrophosphate decarboxylase;... 113 5e-24
UniRef50_Q74JA3 Cluster: Mevalonate pyrophosphate decarboxylase;... 105 1e-21
UniRef50_Q88WB4 Cluster: Diphosphomevalonate decarboxylase; n=6;... 105 1e-21
UniRef50_Q2BIJ8 Cluster: Diphosphomevalonate decarboxylase; n=1;... 103 4e-21
UniRef50_Q83DT5 Cluster: Diphosphomevalonate decarboxylase; n=4;... 101 2e-20
UniRef50_A4VT19 Cluster: Mevalonate pyrophosphate decarboxylase;... 101 2e-20
UniRef50_Q8L1I0 Cluster: Mevalonate diphosphate decarboxylase; n... 99 2e-19
UniRef50_Q23R64 Cluster: Diphosphomevalonate decarboxylase famil... 99 2e-19
UniRef50_A5EVP2 Cluster: Diphosphomevalonate decarboxylase; n=1;... 98 3e-19
UniRef50_Q04EX2 Cluster: Mevalonate pyrophosphate decarboxylase;... 95 3e-18
UniRef50_A7KGY8 Cluster: NapT5; n=2; Streptomyces|Rep: NapT5 - S... 94 4e-18
UniRef50_Q5KSN1 Cluster: Mevalonate diphosphate decarboxylase; n... 94 5e-18
UniRef50_Q038V4 Cluster: Mevalonate pyrophosphate decarboxylase;... 94 5e-18
UniRef50_Q31EU7 Cluster: Diphosphomevalonate decarboxylase; n=1;... 89 2e-16
UniRef50_Q660I4 Cluster: Mevalonate pyrophosphate decarboxylase;... 88 2e-16
UniRef50_A2RID5 Cluster: Diphosphomevalonate decarboxylase; n=4;... 87 7e-16
UniRef50_Q97SI0 Cluster: Diphosphomevalonate decarboxylase; n=39... 86 9e-16
UniRef50_Q5AB67 Cluster: Putative uncharacterized protein; n=1; ... 84 4e-15
UniRef50_A6G139 Cluster: Mevalonate diphosphate decarboxylase; n... 74 4e-12
UniRef50_Q6XYE3 Cluster: FP17780; n=2; Homo sapiens|Rep: FP17780... 74 4e-12
UniRef50_A0M7H5 Cluster: Diphosphomevalonate decarboxylase; n=15... 72 2e-11
UniRef50_Q8SRR7 Cluster: MEVALONATE PYROPHOSPHATE DECARBOXYLASE;... 71 3e-11
UniRef50_Q7QXZ9 Cluster: GLP_479_14176_13169; n=1; Giardia lambl... 68 3e-10
UniRef50_Q9HRQ4 Cluster: Diphosphomevalonate decarboxylase; n=10... 60 5e-08
UniRef50_Q5ZTW8 Cluster: Mevalonate diphosphate decarboxylase; n... 59 2e-07
UniRef50_A4GKI0 Cluster: Cytosolic mevalonate-5-diphosphate deca... 58 4e-07
UniRef50_Q6MMJ9 Cluster: Diphosphomevalonate decarboxylase; n=1;... 55 3e-06
UniRef50_A5V173 Cluster: GHMP kinase, C terminal domain protein;... 46 0.002
UniRef50_Q12FN4 Cluster: Binding-protein-dependent transport sys... 35 3.0
UniRef50_Q6C8L5 Cluster: Yarrowia lipolytica chromosome D of str... 34 4.0
UniRef50_Q18706 Cluster: Putative uncharacterized protein C49C8.... 34 5.3
UniRef50_A7Q958 Cluster: Chromosome chr19 scaffold_66, whole gen... 33 9.2
UniRef50_A2FK64 Cluster: Clan SB, family S8, subtilisin-like ser... 33 9.2
>UniRef50_Q9VXQ3 Cluster: CG8239-PA; n=5; Endopterygota|Rep:
CG8239-PA - Drosophila melanogaster (Fruit fly)
Length = 388
Score = 259 bits (634), Expect = 7e-68
Identities = 127/256 (49%), Positives = 172/256 (67%), Gaps = 3/256 (1%)
Frame = +2
Query: 80 VTVIAPVNIAVIKYWGKRDEKLILPLNDSVSATFDTSVMCAKTSVSTHPDFVEDQIWLNG 259
VT +APVNIA+IKYWGKR E+LILP+NDS+S T T +CAKT+V+ F +++WLNG
Sbjct: 4 VTCVAPVNIALIKYWGKRHEELILPVNDSISMTLSTDELCAKTTVTASESFETNRMWLNG 63
Query: 260 KEESFS-NPRLQNCLREIKSRAVAEKTIAEDVLSWKVHVSSENNFPTXXXXXXXXXXXXC 436
+E F + RLQ CL E+ AVA + + +WK+H++S NNFPT C
Sbjct: 64 EEVPFEESSRLQRCLNEVHRLAVASGS-QKVPPTWKLHIASVNNFPTAAGLASSAAGYAC 122
Query: 437 LVSALAKLYKI--KSDVSSIARLGSGSACRSVYGGFVRWHAGSKPDGSDSIATQIADSNH 610
LV +L++LY I +++++AR GSGSACRS+YGGFV+WH G+ DGSDS+A QIA S+H
Sbjct: 123 LVYSLSRLYDIPLNEELTTVARQGSGSACRSLYGGFVQWHRGALDDGSDSVARQIAPSDH 182
Query: 611 WPEMRVLVLVVGNTQKKVSSTVGMKISSETSELLKHRIQHCVPQRTERIIXAIKNKDFYK 790
WP M VL+LVV + +KK +ST GM+ + +TS+L+KHR+ VP R R+ AI + DF
Sbjct: 183 WPNMHVLILVVNDARKKTASTRGMQQAVKTSQLIKHRVDQVVPDRIIRLREAIASHDFQA 242
Query: 791 FAEIQ*KTVISFMQFA 838
FAEI K F A
Sbjct: 243 FAEITMKDSNQFHAIA 258
Score = 37.5 bits (83), Expect = 0.43
Identities = 15/18 (83%), Positives = 16/18 (88%)
Frame = +1
Query: 802 TMKDSNQFHAICLXSYPP 855
TMKDSNQFHAI L +YPP
Sbjct: 247 TMKDSNQFHAIALDTYPP 264
>UniRef50_A7SHV3 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 406
Score = 257 bits (630), Expect = 2e-67
Identities = 121/243 (49%), Positives = 168/243 (69%), Gaps = 2/243 (0%)
Frame = +2
Query: 80 VTVIAPVNIAVIKYWGKRDEKLILPLNDSVSATFDTSVMCAKTSVSTHPDFVEDQIWLNG 259
VTV AP+NIAVIKYWGKRDE+LILPLN S+SAT + +C T+V D +D +W+N
Sbjct: 20 VTVKAPINIAVIKYWGKRDEELILPLNSSLSATINLDELCTTTTVVARRDNPQDSLWINK 79
Query: 260 KEESFS-NPRLQNCLREIKSRAVAEKTIA-EDVLSWKVHVSSENNFPTXXXXXXXXXXXX 433
+E+ + +PR+Q C+ +++ A +++ ++ + + S+NNFPT
Sbjct: 80 REQPIAESPRIQKCISKVRQLAKENSPERWQELRNYGLCIYSKNNFPTAAGLASSASGYA 139
Query: 434 CLVSALAKLYKIKSDVSSIARLGSGSACRSVYGGFVRWHAGSKPDGSDSIATQIADSNHW 613
CLV AL+KLY + ++SSIAR GSGSACRS+YGGFV+W AG +PDG+DSIA+QI D HW
Sbjct: 140 CLVLALSKLYHLDMELSSIARQGSGSACRSMYGGFVKWEAGCRPDGTDSIASQIVDEKHW 199
Query: 614 PEMRVLVLVVGNTQKKVSSTVGMKISSETSELLKHRIQHCVPQRTERIIXAIKNKDFYKF 793
+R+L+LV+ + +K ST GM+ S+ETSELL+ R Q CVP+R E I AIK +DF+ F
Sbjct: 200 STLRILILVINDERKANPSTSGMRRSTETSELLQFRAQKCVPKRMENITKAIKERDFHTF 259
Query: 794 AEI 802
AEI
Sbjct: 260 AEI 262
Score = 38.7 bits (86), Expect = 0.19
Identities = 19/42 (45%), Positives = 23/42 (54%), Gaps = 1/42 (2%)
Frame = +1
Query: 733 CSPKN*TNYX-SYKEQRLL*ICRDTMKDSNQFHAICLXSYPP 855
C PK N + KE+ TMKDSNQ HA+C +YPP
Sbjct: 239 CVPKRMENITKAIKERDFHTFAEITMKDSNQLHAVCQDTYPP 280
>UniRef50_P53602 Cluster: Diphosphomevalonate decarboxylase (EC
4.1.1.33) (Mevalonate pyrophosphate decarboxylase)
(Mevalonate (diphospho)decarboxylase); n=27;
Coelomata|Rep: Diphosphomevalonate decarboxylase (EC
4.1.1.33) (Mevalonate pyrophosphate decarboxylase)
(Mevalonate (diphospho)decarboxylase) - Homo sapiens
(Human)
Length = 400
Score = 253 bits (620), Expect = 4e-66
Identities = 123/246 (50%), Positives = 156/246 (63%), Gaps = 5/246 (2%)
Frame = +2
Query: 80 VTVIAPVNIAVIKYWGKRDEKLILPLNDSVSATFDTSVMCAKTSVSTHPDFVEDQIWLNG 259
VT APVNIAVIKYWGKRDE+L+LP+N S+S T + T+ DF ED+IWLNG
Sbjct: 10 VTCTAPVNIAVIKYWGKRDEELVLPINSSLSVTLHQDQLKTTTTAVISKDFTEDRIWLNG 69
Query: 260 KEESFSNPRLQNCLREIKSRAVAEKTIAE-----DVLSWKVHVSSENNFPTXXXXXXXXX 424
+EE PRLQ CLREI+ A + + LS KVHV+S NNFPT
Sbjct: 70 REEDVGQPRLQACLREIRCLARKRRNSRDGDPLPSSLSCKVHVASVNNFPTAAGLASSAA 129
Query: 425 XXXCLVSALAKLYKIKSDVSSIARLGSGSACRSVYGGFVRWHAGSKPDGSDSIATQIADS 604
CL LA++Y ++SD+S +AR GSGSACRS+YGGFV W G + DG DSIA Q+A
Sbjct: 130 GYACLAYTLARVYGVESDLSEVARRGSGSACRSLYGGFVEWQMGEQADGKDSIARQVAPE 189
Query: 605 NHWPEMRVLVLVVGNTQKKVSSTVGMKISSETSELLKHRIQHCVPQRTERIIXAIKNKDF 784
+HWPE+RVL+LVV +K STVGM+ S ETS LL+ R + VP R + I+ +DF
Sbjct: 190 SHWPELRVLILVVSAEKKLTGSTVGMRASVETSPLLRFRAESVVPARMAEMARCIRERDF 249
Query: 785 YKFAEI 802
FA++
Sbjct: 250 PSFAQL 255
Score = 37.5 bits (83), Expect = 0.43
Identities = 14/18 (77%), Positives = 16/18 (88%)
Frame = +1
Query: 802 TMKDSNQFHAICLXSYPP 855
TMKDSNQFHA CL ++PP
Sbjct: 256 TMKDSNQFHATCLDTFPP 273
>UniRef50_Q8LAR8 Cluster: Diphosphomevalonate decarboxylase-like
protein; n=17; Eukaryota|Rep: Diphosphomevalonate
decarboxylase-like protein - Arabidopsis thaliana
(Mouse-ear cress)
Length = 419
Score = 248 bits (607), Expect = 1e-64
Identities = 125/252 (49%), Positives = 163/252 (64%), Gaps = 10/252 (3%)
Frame = +2
Query: 77 IVTVIAPVNIAVIKYWGKRDEKLILPLNDSVSATFDTSVMCAKTSVSTHPDFVEDQIWLN 256
+VT P NIAVIKYWGKR E ILP+NDS+S T D +C T+V+ P F D++WLN
Sbjct: 9 MVTAQTPTNIAVIKYWGKRHEVRILPVNDSISVTLDPDHLCTVTTVAVSPAFDRDRMWLN 68
Query: 257 GKEESFSNPRLQNCLREIKSRAV----AEKTIAEDVLSWK---VHVSSENNFPTXXXXXX 415
GKE S S R QNCLREI+ RA EK I W+ +H++S NNFPT
Sbjct: 69 GKEISLSGSRYQNCLREIRGRAGDVEDMEKGIKIRKKDWEKLNLHIASHNNFPTAAGLAS 128
Query: 416 XXXXXXCLVSALAKLYKIKSD---VSSIARLGSGSACRSVYGGFVRWHAGSKPDGSDSIA 586
CLV +LAKL + D +S+IAR GSGSACRS++GGFV+W GSK DGSDS+A
Sbjct: 129 SAAGFACLVFSLAKLMNVDEDPSHLSAIARQGSGSACRSLFGGFVKWTMGSKEDGSDSVA 188
Query: 587 TQIADSNHWPEMRVLVLVVGNTQKKVSSTVGMKISSETSELLKHRIQHCVPQRTERIIXA 766
Q+AD HW ++ +++ VV + QK+ SST GM+ S ETS LL+HR + VP+R ++ A
Sbjct: 189 VQLADEKHWDDLVIIIAVVSSRQKETSSTSGMRESVETSLLLQHRAKEVVPKRILQMEEA 248
Query: 767 IKNKDFYKFAEI 802
IKN+DF F ++
Sbjct: 249 IKNRDFASFTQL 260
>UniRef50_P32377 Cluster: Diphosphomevalonate decarboxylase; n=35;
Fungi/Metazoa group|Rep: Diphosphomevalonate
decarboxylase - Saccharomyces cerevisiae (Baker's yeast)
Length = 396
Score = 245 bits (599), Expect = 1e-63
Identities = 122/245 (49%), Positives = 159/245 (64%), Gaps = 6/245 (2%)
Frame = +2
Query: 83 TVIAPVNIAVIKYWGKRDEKLILPLNDSVSATFDTSVMCAKTSVSTHPDFVEDQIWLNGK 262
+V APVNIA +KYWGKRD KL LP N S+S T + TS +T P+F D +WLNG+
Sbjct: 7 SVTAPVNIATLKYWGKRDTKLNLPTNSSISVTLSQDDLRTLTSAATAPEFERDTLWLNGE 66
Query: 263 EESFSNPRLQNCLREIKS--RAVAEKTIAEDVLS-WKVHVSSENNFPTXXXXXXXXXXXX 433
S N R QNCLR+++ + + K + LS WK+H+ SENNFPT
Sbjct: 67 PHSIDNERTQNCLRDLRQLRKEMESKDASLPTLSQWKLHIVSENNFPTAAGLASSAAGFA 126
Query: 434 CLVSALAKLYKIK---SDVSSIARLGSGSACRSVYGGFVRWHAGSKPDGSDSIATQIADS 604
LVSA+AKLY++ S++S IAR GSGSACRS++GG+V W G DG DS+A QIADS
Sbjct: 127 ALVSAIAKLYQLPQSTSEISRIARKGSGSACRSLFGGYVAWEMGKAEDGHDSMAVQIADS 186
Query: 605 NHWPEMRVLVLVVGNTQKKVSSTVGMKISSETSELLKHRIQHCVPQRTERIIXAIKNKDF 784
+ WP+M+ VLVV + +K VSST GM+++ TSEL K RI+H VP+R E + AI KDF
Sbjct: 187 SDWPQMKACVLVVSDIKKDVSSTQGMQLTVATSELFKERIEHVVPKRFEVMRKAIVEKDF 246
Query: 785 YKFAE 799
FA+
Sbjct: 247 ATFAK 251
Score = 35.9 bits (79), Expect = 1.3
Identities = 13/20 (65%), Positives = 16/20 (80%)
Frame = +1
Query: 796 RDTMKDSNQFHAICLXSYPP 855
++TM DSN FHA CL S+PP
Sbjct: 251 KETMMDSNSFHATCLDSFPP 270
>UniRef50_Q54YQ9 Cluster: Putative uncharacterized protein; n=1;
Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein - Dictyostelium discoideum AX4
Length = 391
Score = 236 bits (578), Expect = 5e-61
Identities = 118/241 (48%), Positives = 155/241 (64%)
Frame = +2
Query: 80 VTVIAPVNIAVIKYWGKRDEKLILPLNDSVSATFDTSVMCAKTSVSTHPDFVEDQIWLNG 259
VT APVNIAVIKYWGKRDE +ILPLN S+S T + T++ D+ ED+++LNG
Sbjct: 6 VTCTAPVNIAVIKYWGKRDENIILPLNSSLSGTLHQDDLKTTTTIVASEDYTEDELYLNG 65
Query: 260 KEESFSNPRLQNCLREIKSRAVAEKTIAEDVLSWKVHVSSENNFPTXXXXXXXXXXXXCL 439
K+E + R QN L+ I+SRA K + + VH++S NNFPT CL
Sbjct: 66 KKEDINAVRYQNVLKMIRSRAT--KLMDKKHC---VHIASINNFPTAAGLASSASGYCCL 120
Query: 440 VSALAKLYKIKSDVSSIARLGSGSACRSVYGGFVRWHAGSKPDGSDSIATQIADSNHWPE 619
V LA++Y + D+S IARLGSGSACRS+YGGFV+W G+K DGSDSIA Q+ +HWP+
Sbjct: 121 VFTLAQMYGVDGDISGIARLGSGSACRSMYGGFVKWEMGTKDDGSDSIAVQVQPESHWPD 180
Query: 620 MRVLVLVVGNTQKKVSSTVGMKISSETSELLKHRIQHCVPQRTERIIXAIKNKDFYKFAE 799
M ++VLVV + +K+ SST GM+ S+ TS ++K R VP R I AI KDF F +
Sbjct: 181 MNIIVLVVNDKKKETSSTDGMQKSAATSVMMKERCAVTVPNRMRDIEEAINKKDFQTFGD 240
Query: 800 I 802
I
Sbjct: 241 I 241
>UniRef50_Q4P3Y4 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 427
Score = 223 bits (545), Expect = 4e-57
Identities = 112/250 (44%), Positives = 160/250 (64%), Gaps = 10/250 (4%)
Frame = +2
Query: 83 TVIAPVNIAVIKYWGKRDEKLILPLNDSVSATFDTSVMCAKTSVSTHPDF-VEDQIWLNG 259
T APVNIAVIKYWGK+D LILP NDS+S T D + + T+ F +D++WLNG
Sbjct: 9 TCSAPVNIAVIKYWGKKDTTLILPTNDSLSVTLDQDHLRSVTTARADASFGSQDRLWLNG 68
Query: 260 KEESF-SNPRLQNCLREIKSRAVAEKTIAEDVLS---WKVHVSSENNFPTXXXXXXXXXX 427
+EE+ ++ RL+ C+ E++ A+++ ++ W VHV SENNFPT
Sbjct: 69 EEEAIKADGRLRRCIDEMRKLRQAKESKDSNLAKLSEWAVHVCSENNFPTAAGLASSASG 128
Query: 428 XXCLVSALAKLYKIKSDVSS-----IARLGSGSACRSVYGGFVRWHAGSKPDGSDSIATQ 592
L+++LA LY+++ +VSS IAR GSGSACRS++GG+V W G P G DS+A Q
Sbjct: 129 FAALIASLAALYELQPEVSSSELSRIARQGSGSACRSLFGGYVAWQGGEHPSGQDSLAVQ 188
Query: 593 IADSNHWPEMRVLVLVVGNTQKKVSSTVGMKISSETSELLKHRIQHCVPQRTERIIXAIK 772
+A +HWP+++ L+ VV + +K ST GM+ + +TS LL+HRI+ VPQR +I AI+
Sbjct: 189 VAPQSHWPDLQALICVVSDAKKGTPSTAGMQRTVQTSPLLQHRIKEVVPQRMIKISEAIQ 248
Query: 773 NKDFYKFAEI 802
+DF FAEI
Sbjct: 249 KQDFNTFAEI 258
>UniRef50_Q4QE40 Cluster: Diphosphomevalonate decarboxylase,
putative; n=8; Trypanosomatidae|Rep: Diphosphomevalonate
decarboxylase, putative - Leishmania major
Length = 383
Score = 222 bits (542), Expect = 1e-56
Identities = 115/244 (47%), Positives = 150/244 (61%), Gaps = 3/244 (1%)
Frame = +2
Query: 80 VTVIAPVNIAVIKYWGKRD--EKLILPLNDSVSATFDTSVMCAKTSVSTHPDFVEDQIWL 253
VTV AP+NIA IKYWGKR+ E LILP NDS S T T +KTSV D ED++WL
Sbjct: 7 VTVEAPINIAFIKYWGKREGGETLILPTNDSFSITLSTKPFRSKTSVELRSDASEDELWL 66
Query: 254 NGKEESFSN-PRLQNCLREIKSRAVAEKTIAEDVLSWKVHVSSENNFPTXXXXXXXXXXX 430
NGK+ + PR+Q+ L I+ ++ + K ++ SENNFPT
Sbjct: 67 NGKKSNIQETPRIQSVLSCIRDNC------PDNTKNLKAYIVSENNFPTAAGMASSASGY 120
Query: 431 XCLVSALAKLYKIKSDVSSIARLGSGSACRSVYGGFVRWHAGSKPDGSDSIATQIADSNH 610
L +AL K Y DVS ++RLGSGSACRSVYGGFV WH G KPDG+D IATQ D +
Sbjct: 121 CALAAALVKAYGATVDVSMLSRLGSGSACRSVYGGFVIWHKGEKPDGTDCIATQFLDEKY 180
Query: 611 WPEMRVLVLVVGNTQKKVSSTVGMKISSETSELLKHRIQHCVPQRTERIIXAIKNKDFYK 790
WPE++V+ V+ +K VSST GM+ S +TS +++ RI+ VP R + AI+ +DF +
Sbjct: 181 WPEVQVMCAVLKGEKKDVSSTSGMQQSLKTSSMMRERIESIVPARMSAVKEAIQQRDFNQ 240
Query: 791 FAEI 802
FA I
Sbjct: 241 FAAI 244
>UniRef50_UPI0000E24443 Cluster: PREDICTED: diphosphomevalonate
decarboxylase isoform 1; n=1; Pan troglodytes|Rep:
PREDICTED: diphosphomevalonate decarboxylase isoform 1 -
Pan troglodytes
Length = 434
Score = 124 bits (299), Expect(2) = 1e-56
Identities = 63/128 (49%), Positives = 76/128 (59%), Gaps = 5/128 (3%)
Frame = +2
Query: 80 VTVIAPVNIAVIKYWGKRDEKLILPLNDSVSATFDTSVMCAKTSVSTHPDFVEDQIWLNG 259
VT APVNIAVIKYWGKRDE+L+LP+N S+S T + T+ DF ED+IWLNG
Sbjct: 10 VTCTAPVNIAVIKYWGKRDEELVLPINSSLSVTLHQDQLKTTTTAVISKDFTEDRIWLNG 69
Query: 260 KEESFSNPRLQNCLREIKSRAVAEKTIAE-----DVLSWKVHVSSENNFPTXXXXXXXXX 424
+EE PRLQ CLREI+ A + + LS KVHV+S NNFPT
Sbjct: 70 REEDVGQPRLQACLREIRCLARKRRNSRDGDPLPSSLSCKVHVASVNNFPTAAGLASSAA 129
Query: 425 XXXCLVSA 448
CLV+A
Sbjct: 130 GYACLVAA 137
Score = 119 bits (287), Expect(2) = 1e-56
Identities = 54/118 (45%), Positives = 75/118 (63%)
Frame = +2
Query: 449 LAKLYKIKSDVSSIARLGSGSACRSVYGGFVRWHAGSKPDGSDSIATQIADSNHWPEMRV 628
LA++Y ++SD+S +AR GSGSACRS+YGGFV W G + DG DSIA Q+A +HWPE+RV
Sbjct: 172 LARVYGVESDLSEVARRGSGSACRSLYGGFVEWQMGEQADGKDSIARQVAPESHWPELRV 231
Query: 629 LVLVVGNTQKKVSSTVGMKISSETSELLKHRIQHCVPQRTERIIXAIKNKDFYKFAEI 802
L+LVV + G+ ET L+ R + VP R + I+ +DF FA++
Sbjct: 232 LILVVSGVGRVEQQPCGLSAPWETPCALQFRAESVVPARMAEMARCIRERDFPSFAQL 289
Score = 37.5 bits (83), Expect = 0.43
Identities = 14/18 (77%), Positives = 16/18 (88%)
Frame = +1
Query: 802 TMKDSNQFHAICLXSYPP 855
TMKDSNQFHA CL ++PP
Sbjct: 290 TMKDSNQFHATCLDTFPP 307
>UniRef50_Q0E4P1 Cluster: Os02g0107200 protein; n=2; Oryza sativa
(japonica cultivar-group)|Rep: Os02g0107200 protein -
Oryza sativa subsp. japonica (Rice)
Length = 553
Score = 221 bits (539), Expect = 2e-56
Identities = 113/222 (50%), Positives = 141/222 (63%), Gaps = 10/222 (4%)
Frame = +2
Query: 92 APVNIAVIKYWGKRDEKLILPLNDSVSATFDTSVMCAKTSVSTHPDFVEDQIWLNGKEES 271
+P NIAVIKYWGKRDE LILP+NDS+S T D + A T+V+ P F D++WLNGKE S
Sbjct: 331 SPTNIAVIKYWGKRDEALILPVNDSISVTLDPDHLSATTTVAVSPSFPSDRMWLNGKEIS 390
Query: 272 FSNPRLQNCLREIKSRAV----AEKTIAEDVLSW---KVHVSSENNFPTXXXXXXXXXXX 430
S R Q+CLREI+ RA +K I W VH++S NNFPT
Sbjct: 391 LSGGRFQSCLREIRKRAQDVEDEKKGIRIKKEDWGKLHVHIASYNNFPTAAGLASSVAGL 450
Query: 431 XCLVSALAKLYKIKSD---VSSIARLGSGSACRSVYGGFVRWHAGSKPDGSDSIATQIAD 601
C V L L +K D +SSIAR GSGSACRS+YGGFV+W G DGSDSIA Q+AD
Sbjct: 451 VCFVFTLGNLMNVKEDYGELSSIARQGSGSACRSIYGGFVKWCMGKNNDGSDSIAVQLAD 510
Query: 602 SNHWPEMRVLVLVVGNTQKKVSSTVGMKISSETSELLKHRIQ 727
HW ++ +++ VV + QK+ SST GM+ S ETS LL++R Q
Sbjct: 511 EAHWNDLVIIIAVVSSKQKETSSTSGMRDSVETSPLLQYRAQ 552
>UniRef50_A3A295 Cluster: Putative uncharacterized protein; n=2;
Oryza sativa|Rep: Putative uncharacterized protein -
Oryza sativa subsp. japonica (Rice)
Length = 493
Score = 221 bits (539), Expect = 2e-56
Identities = 113/222 (50%), Positives = 141/222 (63%), Gaps = 10/222 (4%)
Frame = +2
Query: 92 APVNIAVIKYWGKRDEKLILPLNDSVSATFDTSVMCAKTSVSTHPDFVEDQIWLNGKEES 271
+P NIAVIKYWGKRDE LILP+NDS+S T D + A T+V+ P F D++WLNGKE S
Sbjct: 270 SPTNIAVIKYWGKRDEALILPVNDSISVTLDPDHLSATTTVAVSPSFPSDRMWLNGKEIS 329
Query: 272 FSNPRLQNCLREIKSRAV----AEKTIAEDVLSW---KVHVSSENNFPTXXXXXXXXXXX 430
S R Q+CLREI+ RA +K I W VH++S NNFPT
Sbjct: 330 LSGGRFQSCLREIRKRAQDVEDEKKGIRIKKEDWGKLHVHIASYNNFPTAAGLASSVAGL 389
Query: 431 XCLVSALAKLYKIKSD---VSSIARLGSGSACRSVYGGFVRWHAGSKPDGSDSIATQIAD 601
C V L L +K D +SSIAR GSGSACRS+YGGFV+W G DGSDSIA Q+AD
Sbjct: 390 VCFVFTLGNLMNVKEDYGELSSIARQGSGSACRSIYGGFVKWCMGKNNDGSDSIAVQLAD 449
Query: 602 SNHWPEMRVLVLVVGNTQKKVSSTVGMKISSETSELLKHRIQ 727
HW ++ +++ VV + QK+ SST GM+ S ETS LL++R Q
Sbjct: 450 EAHWNDLVIIIAVVSSKQKETSSTSGMRDSVETSPLLQYRAQ 491
>UniRef50_Q1DZV7 Cluster: Putative uncharacterized protein; n=1;
Coccidioides immitis|Rep: Putative uncharacterized
protein - Coccidioides immitis
Length = 621
Score = 194 bits (474), Expect = 2e-48
Identities = 109/247 (44%), Positives = 151/247 (61%), Gaps = 10/247 (4%)
Frame = +2
Query: 92 APVNIAVIKYWGKRDEKLILPLNDSVSATFDTSVMCAKTSVS---THPDFVEDQIWLNGK 262
APVNIAVIKYWGKRD L LP N S+S T + + A T+ S ++P D + LN K
Sbjct: 233 APVNIAVIKYWGKRDATLNLPTNSSLSVTLSQANLRAHTTASCSDSYPHAEGDTLVLNSK 292
Query: 263 EESF-SNPRLQNCLREIK--SRAVAEKTIAEDVLS-WKVHVSSENNFPTXXXXXXXXXXX 430
++ ++ R CL +++ RA+ + + LS + + + SENNFPT
Sbjct: 293 PQNIHASKRTLACLADLRILRRALEDADPSLPRLSAFPLRIVSENNFPTAAGLASSAAGF 352
Query: 431 XCLVSALAKLYKIK---SDVSSIARLGSGSACRSVYGGFVRWHAGSKPDGSDSIATQIAD 601
LV A+A LY + S++S IAR GSGSACRS+ GG+V W +G+K DGSDS+A Q+A
Sbjct: 353 AALVRAVADLYDLPQSPSELSRIARQGSGSACRSLMGGYVAWKSGAKEDGSDSLAEQVAP 412
Query: 602 SNHWPEMRVLVLVVGNTQKKVSSTVGMKISSETSELLKHRIQHCVPQRTERIIXAIKNKD 781
++HWPEMR L+LVV + +K V ST GM+ + TS L R+ VP+R + AI+N+D
Sbjct: 413 ASHWPEMRALILVVSDAKKDVPSTEGMQATRATSTLFPFRVTSVVPERMAAMEKAIQNRD 472
Query: 782 FYKFAEI 802
F FAEI
Sbjct: 473 FASFAEI 479
Score = 33.9 bits (74), Expect = 5.3
Identities = 12/18 (66%), Positives = 15/18 (83%)
Frame = +1
Query: 802 TMKDSNQFHAICLXSYPP 855
TM+DSN FHA CL ++PP
Sbjct: 480 TMRDSNNFHATCLDTWPP 497
>UniRef50_Q29CM9 Cluster: GA20922-PA; n=1; Drosophila
pseudoobscura|Rep: GA20922-PA - Drosophila pseudoobscura
(Fruit fly)
Length = 340
Score = 186 bits (453), Expect = 6e-46
Identities = 90/200 (45%), Positives = 128/200 (64%), Gaps = 3/200 (1%)
Frame = +2
Query: 194 MCAKTSVSTHPDFVEDQIWLNGKEESFS-NPRLQNCLREIKSRAVAEKTIAEDVLSWKVH 370
+CAKT+++ F +++WLN +E F + RL CL+ ++ A + E L WKVH
Sbjct: 142 LCAKTTITASEKFQHNRMWLNDEELLFEEDSRLMRCLKGVQRLAHINGS-QEASLCWKVH 200
Query: 371 VSSENNFPTXXXXXXXXXXXXCLVSALAKLYKIK--SDVSSIARLGSGSACRSVYGGFVR 544
++S NNFPT CLV +LA+LY I ++++IAR GSGSACRS++GGFV+
Sbjct: 201 IASRNNFPTAAGLASSAAGYACLVYSLARLYGIPLTEELTTIARQGSGSACRSLFGGFVQ 260
Query: 545 WHAGSKPDGSDSIATQIADSNHWPEMRVLVLVVGNTQKKVSSTVGMKISSETSELLKHRI 724
WH G DGSDS+A +A + HWP M VL+LVV + +KK SST GM+ S TS+L++HR+
Sbjct: 261 WHRGVLDDGSDSVAEPVASAQHWPNMHVLILVVNDERKKTSSTTGMQRSVTTSQLIQHRV 320
Query: 725 QHCVPQRTERIIXAIKNKDF 784
VP+R + AIK +DF
Sbjct: 321 DKLVPERIANLKKAIKARDF 340
>UniRef50_Q9U294 Cluster: Putative uncharacterized protein; n=3;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 377
Score = 175 bits (427), Expect = 9e-43
Identities = 97/252 (38%), Positives = 146/252 (57%), Gaps = 12/252 (4%)
Frame = +2
Query: 83 TVIAPVNIAVIKYWGKRDEKLILPLNDSVSATFDTSVMCAKTSVSTHPDFVEDQIWLNGK 262
TV P+NIA++KYWGKRD+ LILPLNDS+S T D + A+T++ P + + +NGK
Sbjct: 13 TVRVPMNIALVKYWGKRDDLLILPLNDSISLTVDR--LTAETTIRMVPGVGKHTVEINGK 70
Query: 263 E-ESFSNPRLQN----CLREIKSRAVAEKTIAED------VLSWKVHVSSENNFPTXXXX 409
E SN R Q LR + R AE + A+ + + HV+S NFP
Sbjct: 71 SVELSSNKRYQTVFDEALRLQRKRKEAEASSADSNGNDPPPIFYHFHVTSTTNFPVAAGL 130
Query: 410 XXXXXXXXCLVSALAKLYKIK-SDVSSIARLGSGSACRSVYGGFVRWHAGSKPDGSDSIA 586
+ A+ ++ ++ S + +AR+GSGSACRS+YGG V W G DGSD +A
Sbjct: 131 ASSAAGFAAIALAIQRILRLDDSQANRLARIGSGSACRSMYGGLVHWRKGEMDDGSDCLA 190
Query: 587 TQIADSNHWPEMRVLVLVVGNTQKKVSSTVGMKISSETSELLKHRIQHCVPQRTERIIXA 766
+ + +W ++ ++LV + +KKV S+ GM+ S ETS+LLKHRI+ VPQR ++I A
Sbjct: 191 VRTEAAANWEDLYCIILVFDDGRKKVGSSEGMRRSRETSQLLKHRIESIVPQRIQQIQEA 250
Query: 767 IKNKDFYKFAEI 802
+++F + A +
Sbjct: 251 YTSRNFEQLARV 262
Score = 34.7 bits (76), Expect = 3.0
Identities = 14/31 (45%), Positives = 19/31 (61%)
Frame = +1
Query: 763 SYKEQRLL*ICRDTMKDSNQFHAICLXSYPP 855
+Y + + R M DSNQFHA+C+ S PP
Sbjct: 250 AYTSRNFEQLARVIMADSNQFHAVCMDSTPP 280
>UniRef50_Q4J9D9 Cluster: Diphosphomevalonate decarboxylase; n=4;
Sulfolobaceae|Rep: Diphosphomevalonate decarboxylase -
Sulfolobus acidocaldarius
Length = 325
Score = 138 bits (335), Expect = 1e-31
Identities = 89/243 (36%), Positives = 131/243 (53%), Gaps = 8/243 (3%)
Frame = +2
Query: 89 IAPVNIAVIKYWGKRDEKLILPLNDSVSATFDTSVMCAKTSVSTHPDFVEDQIWLNG--- 259
IAP NIA++KYWGKRD+KL LPLN S+S + + + K +VS D +D+I++N
Sbjct: 8 IAPSNIAIVKYWGKRDDKLNLPLNSSLSISLEKLEVRTKVTVSA--DLQKDEIYINQQKL 65
Query: 260 KEESFSN--PRLQNCLREIKSRAVAEKTIAEDVLSWKVHVSSENNFPTXXXXXXXXXXXX 433
+EE F R+ N RE+ + + V V S NFP
Sbjct: 66 REEEFEEYGGRVINIFRELYGK------------KFSVKVESYMNFPKSVGLASSAAGIA 113
Query: 434 CLVSALAKLYKI---KSDVSSIARLGSGSACRSVYGGFVRWHAGSKPDGSDSIATQIADS 604
LV AL + + ++S IAR+GSGSACRS GGFV W GS+ DG DS QI
Sbjct: 114 ALVYALNDALGLGLSQRELSKIARIGSGSACRSTIGGFVIWEKGSQEDGEDSYCYQIFPE 173
Query: 605 NHWPEMRVLVLVVGNTQKKVSSTVGMKISSETSELLKHRIQHCVPQRTERIIXAIKNKDF 784
+HW ++ ++ ++ +KKVSS GMK ++ +S L++ R++ + +I +IK KD
Sbjct: 174 DHWEDLIDIIPLIQLKEKKVSSRKGMKNTALSSSLMECRLKF-IEDTLPLVIDSIKKKDE 232
Query: 785 YKF 793
+F
Sbjct: 233 KEF 235
>UniRef50_Q1D2F0 Cluster: Diphosphomevalonate decarboxylase; n=2;
Cystobacterineae|Rep: Diphosphomevalonate decarboxylase
- Myxococcus xanthus (strain DK 1622)
Length = 332
Score = 126 bits (303), Expect = 9e-28
Identities = 79/213 (37%), Positives = 113/213 (53%), Gaps = 6/213 (2%)
Frame = +2
Query: 83 TVIAPVNIAVIKYWGKRDEKLILPLNDSVSATFDTSVMCAKTSVSTHPDF--VEDQIWLN 256
T +A NIA++KYWGKRD+ LILP S+S T + SV+T +F DQ+ LN
Sbjct: 8 TALAHPNIALVKYWGKRDDALILPHQSSLSLTL------SPLSVTTTVEFGAASDQVELN 61
Query: 257 GKEESFSN-PRLQNCLREIKSRAVAEKTIAEDVLSWKVHVSSENNFPTXXXXXXXXXXXX 433
G S R+ L ++++A A+ A+ V S +FP
Sbjct: 62 GHTAKGSERDRVLRLLELVRAQAKADLGPAK--------VVSRGDFPMAAGLASSAAGFA 113
Query: 434 CLVSALAKLYKIKSD---VSSIARLGSGSACRSVYGGFVRWHAGSKPDGSDSIATQIADS 604
L A + S+ S +AR+GSGSACRSV GGF W G +PDG DS A Q D+
Sbjct: 114 ALAVAGRAAAGLPSEPRAASILARMGSGSACRSVQGGFCEWQRGERPDGEDSFAVQRFDA 173
Query: 605 NHWPEMRVLVLVVGNTQKKVSSTVGMKISSETS 703
HWP++R++V ++ +K+V S GMK++ +TS
Sbjct: 174 AHWPDVRMVVAILDRGEKEVKSRDGMKLTVDTS 206
>UniRef50_Q8YAV2 Cluster: Lmo0011 protein; n=18; Bacilli|Rep:
Lmo0011 protein - Listeria monocytogenes
Length = 323
Score = 125 bits (302), Expect = 1e-27
Identities = 87/243 (35%), Positives = 120/243 (49%), Gaps = 3/243 (1%)
Frame = +2
Query: 83 TVIAPVNIAVIKYWGKRDEKLILPLNDSVSATFDTSVMCAKTSVSTHPDFVEDQIWLNGK 262
T IA N+A+IKYWGKRDE LILP N S+S T D KT+V +D LN +
Sbjct: 4 TAIAHTNVALIKYWGKRDEHLILPANSSLSFTVDK--FYTKTTVEWDEKLTQDTFILNNE 61
Query: 263 EESFSNPRLQNCLREIKSRAVAEKTIAEDVLSWKVHVSSENNFPTXXXXXXXXXXXXCLV 442
+++ + K +K E +S K ++SEN+ PT L
Sbjct: 62 QKT-----------DAKVARFIDKMREEFGISAKAKITSENHVPTAAGLASSASAFAALA 110
Query: 443 ---SALAKLYKIKSDVSSIARLGSGSACRSVYGGFVRWHAGSKPDGSDSIATQIADSNHW 613
S A K +S +AR GSGSA RSV+G FV W G DGSDS A +
Sbjct: 111 LAGSNAAGRKDTKEYISRLARFGSGSASRSVFGDFVIWEKGELADGSDSFAVPFT-NKLC 169
Query: 614 PEMRVLVLVVGNTQKKVSSTVGMKISSETSELLKHRIQHCVPQRTERIIXAIKNKDFYKF 793
+M ++V VV + +KKVSS GM+++ ETS ++ + E + AI ++DF K
Sbjct: 170 DKMSLVVAVVSDKEKKVSSRDGMRLTVETSPFFENWVS-AAEIDLEEMKQAILDEDFIKV 228
Query: 794 AEI 802
EI
Sbjct: 229 GEI 231
>UniRef50_A0CNB5 Cluster: Chromosome undetermined scaffold_22, whole
genome shotgun sequence; n=1; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_22,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 372
Score = 119 bits (286), Expect = 1e-25
Identities = 76/253 (30%), Positives = 133/253 (52%), Gaps = 19/253 (7%)
Frame = +2
Query: 101 NIAVIKYWGKRDEKLILPLNDSVSATFDTSVMCAKTSVSTHPDFVEDQIWLNGKEESFSN 280
NI +IKYWGK +E+ I+PLN ++ T + + T+++ +P+ ++Q+ +NGK+ SN
Sbjct: 20 NIGLIKYWGKWNEREIIPLNTNIGVTLNPKDIFTTTTLTLNPETDKNQLLINGKDFHISN 79
Query: 281 --PRLQNCLRE--IKSRAVA---------EKTIAE---DVLSWKVHVSSENNFPTXXXXX 412
RL RE ++S+ A +K + + D+ + + V S N+FPT
Sbjct: 80 RIERLFGIFREQILQSKQFASNKYKNSPSDKPLGQVIPDIEKYGIRVESNNSFPTGSGLA 139
Query: 413 XXXXXXXCLVSALAKLYKIKSDVSSIARLGSGSACRSVYGGFVRWHAGSKPDGSDSIATQ 592
L L + K DV ++R+GSGSACR +YG V + + + +
Sbjct: 140 SSSSGLSALALCLQDILKTDIDVRYLSRIGSGSACRCLYGNLVLFPETISLESKRCLPYE 199
Query: 593 IADSNHWPEMRVLVLVVGNT---QKKVSSTVGMKISSETSELLKHRIQHCVPQRTERIIX 763
+ S+ W + +V ++++ +T QK V S GMK++ ETS+L++ R++ V Q +
Sbjct: 200 V-QSSKWLKDKVSIVILTDTHQGQKDVLSKDGMKLTWETSKLIQGRVRQYVEQHITELQS 258
Query: 764 AIKNKDFYKFAEI 802
A++ +DF K EI
Sbjct: 259 ALEKQDFNKVMEI 271
Score = 34.7 bits (76), Expect = 3.0
Identities = 12/17 (70%), Positives = 15/17 (88%)
Frame = +1
Query: 805 MKDSNQFHAICLXSYPP 855
+KDSNQFHA C+ +YPP
Sbjct: 273 IKDSNQFHATCMDTYPP 289
>UniRef50_Q9FD68 Cluster: Mevalonate diphosphate decarboxylase;
n=22; Bacilli|Rep: Mevalonate diphosphate decarboxylase
- Enterococcus faecalis (Streptococcus faecalis)
Length = 331
Score = 116 bits (279), Expect = 8e-25
Identities = 80/240 (33%), Positives = 118/240 (49%), Gaps = 3/240 (1%)
Frame = +2
Query: 92 APVNIAVIKYWGKRDEKLILPLNDSVSATFDTSVMCAKTSVSTHPDFVEDQIWLNGKEES 271
A NIA+IKYWGK +E+ ILP+N S+S T D +T+V+ + ED LNG
Sbjct: 8 AHTNIALIKYWGKANEEYILPMNSSLSLTLDA--FYTETTVTFDAHYSEDVFILNGI--- 62
Query: 272 FSNPRLQNCLREIKSRAVAEKTIAEDVLSWKVHVSSENNFPTXXXXXXXXXXXXCLVSAL 451
LQN + K + + +W V S+N PT L A
Sbjct: 63 -----LQNEKQTKKVKEFLNLVRQQADCTWFAKVESQNFVPTAAGLASSASGLAALAGAC 117
Query: 452 AKLYKIK---SDVSSIARLGSGSACRSVYGGFVRWHAGSKPDGSDSIATQIADSNHWPEM 622
+ D+S +AR GSGSACRS++GGF +W+ G + S A I +N E+
Sbjct: 118 NVALGLNLSAKDLSRLARRGSGSACRSIFGGFAQWNKGHSDE--TSFAENIPANNWENEL 175
Query: 623 RVLVLVVGNTQKKVSSTVGMKISSETSELLKHRIQHCVPQRTERIIXAIKNKDFYKFAEI 802
+L +++ + +K VSS GMK + ETS + + + V + ++ AIK KDF + EI
Sbjct: 176 AMLFILINDGEKDVSSRDGMKRTVETSSFYQGWLDN-VEKDLSQVHEAIKTKDFPRLGEI 234
>UniRef50_Q0LPG3 Cluster: Diphosphomevalonate decarboxylase; n=1;
Herpetosiphon aurantiacus ATCC 23779|Rep:
Diphosphomevalonate decarboxylase - Herpetosiphon
aurantiacus ATCC 23779
Length = 334
Score = 115 bits (277), Expect = 1e-24
Identities = 79/247 (31%), Positives = 123/247 (49%), Gaps = 8/247 (3%)
Frame = +2
Query: 65 KMSNIVTVIAPVNIAVIKYWGKRDEKLILPLNDSVSATFDTSVMCAKTSVSTHPDFVEDQ 244
++S+ T +A NIA IKYWG+ D +L LP N S+S D + +T+V P+ V+D
Sbjct: 3 QLSHAATAVACANIAFIKYWGQHDSQLTLPTNGSISMNLDGCL--TETTVQCLPEAVDDS 60
Query: 245 IWL---NGKEESFSNPRLQNCLREI-KSRAVAEKTIAEDVLSWKVHVSSENNFPTXXXXX 412
+WL G+E + + +++I + R +A T +V V S NNFP+
Sbjct: 61 VWLALSGGEEVQAKGRQFERVIQQIERLRQLAGVT-------ERVEVRSRNNFPSDAGIA 113
Query: 413 XXXXXXXCLVSALAKLYKIKSDVSSIARL----GSGSACRSVYGGFVRWHAGSKPDGSDS 580
L A A ++++ D + ++RL GSGSACRS+ GFV W+ G S
Sbjct: 114 SSAAAFAALTRAAASAFRLELDEAELSRLTRLSGSGSACRSIPAGFVEWYNDGTHAG--S 171
Query: 581 IATQIADSNHWPEMRVLVLVVGNTQKKVSSTVGMKISSETSELLKHRIQHCVPQRTERII 760
A QIA HW + +V V+ K V+ST G +++ TS R++ + QR +
Sbjct: 172 YAAQIAPPEHW-NLVDIVAVISTEAKHVASTSGHSVAT-TSPYFSVRLEG-IEQRLADVR 228
Query: 761 XAIKNKD 781
I +D
Sbjct: 229 QGILERD 235
>UniRef50_A2EGU1 Cluster: Diphosphomevalonate decarboxylase family
protein; n=1; Trichomonas vaginalis G3|Rep:
Diphosphomevalonate decarboxylase family protein -
Trichomonas vaginalis G3
Length = 341
Score = 115 bits (277), Expect = 1e-24
Identities = 84/245 (34%), Positives = 118/245 (48%), Gaps = 11/245 (4%)
Frame = +2
Query: 101 NIAVIKYWGKRDEKLILPLNDSVSATFDTSVMCAKTSVSTHPDFVEDQIWLNGKEESFSN 280
NIA++KYWGK + I P++ S+S T + V K S+ D V D +LN KE
Sbjct: 19 NIALVKYWGKENIPEITPIHGSLSVTLNFGVTTTKAEYSS--DDV-DHFYLNNKEA---- 71
Query: 281 PRLQNCLREIKSRAVAEKTIAEDVLSWKVHVSSENNFPTXXXXXXXXXXXXCLVSALAKL 460
EI SR D +++S N+FPT V ALA L
Sbjct: 72 --------EITSRLKTAIDFFNDNGKLHFNITSVNSFPTAAGLASSAAGAAAFVGALASL 123
Query: 461 ---------YKIKS--DVSSIARLGSGSACRSVYGGFVRWHAGSKPDGSDSIATQIADSN 607
Y ++ D++++AR SGS CRS++GGFV W G+ S+S+A QIAD +
Sbjct: 124 VGKTNNPITYWMQKGVDLTALARKVSGSGCRSIHGGFVEWVPGTP---SESVAKQIADQH 180
Query: 608 HWPEMRVLVLVVGNTQKKVSSTVGMKISSETSELLKHRIQHCVPQRTERIIXAIKNKDFY 787
W + V ++V + +K V ST GM+ + ET + R Q VP+R I KDF
Sbjct: 181 QWEDFVVFSVIVSSKKKDVLSTKGMQSTVETVPWIHWRAQEVVPKRISDAKKFINEKDFA 240
Query: 788 KFAEI 802
AEI
Sbjct: 241 SLAEI 245
>UniRef50_Q03FN8 Cluster: Mevalonate pyrophosphate decarboxylase;
n=1; Pediococcus pentosaceus ATCC 25745|Rep: Mevalonate
pyrophosphate decarboxylase - Pediococcus pentosaceus
(strain ATCC 25745 / 183-1w)
Length = 327
Score = 113 bits (272), Expect = 5e-24
Identities = 79/240 (32%), Positives = 114/240 (47%), Gaps = 3/240 (1%)
Frame = +2
Query: 92 APVNIAVIKYWGKRDEKLILPLNDSVSATFDTSVMCAKTSVSTHPDFVEDQIWLNGKEES 271
A NIA++KYWGK + LILP NDS+S T D T V+ ++ + +LN +
Sbjct: 10 AHTNIALLKYWGKINSDLILPANDSISLTLDK--FYTDTEVTFSDEYTSNLFYLN--HQL 65
Query: 272 FSNPRLQNCLREIKSRAVAEKTIAEDVLSWKVHVSSENNFPTXXXXXXXXXXXXCLVSAL 451
++Q R V E +E + SEN+ PT L A
Sbjct: 66 IDVKKMQRINR------VLEAVKSEFGYQGFAKIESENHVPTAAGLASSASGMAALAGAA 119
Query: 452 AKLYKIKSD---VSSIARLGSGSACRSVYGGFVRWHAGSKPDGSDSIATQIADSNHWPEM 622
+D +S +ARLGSGSA RSV+GG V WH G D S A QI S ++
Sbjct: 120 VSALGSHTDLTNLSRLARLGSGSASRSVFGGIVHWHRGY--DHQSSFAEQIV-SEDQIDL 176
Query: 623 RVLVLVVGNTQKKVSSTVGMKISSETSELLKHRIQHCVPQRTERIIXAIKNKDFYKFAEI 802
++ +V+ QKKV ST+GM+ ++ TS ++ Q +I A++N DF K E+
Sbjct: 177 NMVTIVIDRRQKKVKSTLGMQHTASTSPFYPAWVE-ATNQAIPEMISAVQNNDFTKIGEL 235
>UniRef50_Q74JA3 Cluster: Mevalonate pyrophosphate decarboxylase;
n=7; Lactobacillus|Rep: Mevalonate pyrophosphate
decarboxylase - Lactobacillus johnsonii
Length = 321
Score = 105 bits (253), Expect = 1e-21
Identities = 82/244 (33%), Positives = 118/244 (48%), Gaps = 4/244 (1%)
Frame = +2
Query: 83 TVIAPVNIAVIKYWGKRDEKLILPLNDSVSATFDTSVMCAKTSVSTHPDFVEDQIWLNGK 262
T A NIA+IKYWGK D+ L PL S+S T D T+ ED LN +
Sbjct: 4 TARAHTNIALIKYWGKADQALKTPLMSSLSMTLDA--FYTDTTFEHDSSLTEDTFILNDQ 61
Query: 263 EESFSNP-RLQNCLREIKSRAVAEKTIAEDVLSWKVHVSSENNFPTXXXXXXXXXXXXCL 439
++S + R+ N + ++ EK D + + S N+ PT L
Sbjct: 62 KQSVEDSKRVFNYIHLLQ-----EKFGVNDHFT----IRSTNHVPTSAGLASSASAFAAL 112
Query: 440 VSALAKLYKI---KSDVSSIARLGSGSACRSVYGGFVRWHAGSKPDGSDSIATQIADSNH 610
++ Y + K ++S +ARLGSGSA RSVYGGFV W G D S A I D N
Sbjct: 113 ATSFVASYGLDLSKKELSRLARLGSGSATRSVYGGFVEWKKGF--DDESSYAAPI-DENP 169
Query: 611 WPEMRVLVLVVGNTQKKVSSTVGMKISSETSELLKHRIQHCVPQRTERIIXAIKNKDFYK 790
++ +L + V QKK+SST GM++ ++TS + + + E I AI+N DF +
Sbjct: 170 DLDLSLLAIEVNTKQKKISSTKGMQL-AQTSPFYQPWLARNEEEIAE-IKQAIQNNDFTR 227
Query: 791 FAEI 802
E+
Sbjct: 228 IGEL 231
>UniRef50_Q88WB4 Cluster: Diphosphomevalonate decarboxylase; n=6;
Lactobacillus|Rep: Diphosphomevalonate decarboxylase -
Lactobacillus plantarum
Length = 325
Score = 105 bits (252), Expect = 1e-21
Identities = 71/205 (34%), Positives = 107/205 (52%), Gaps = 4/205 (1%)
Frame = +2
Query: 80 VTVIAPVNIAVIKYWGKRDEKLILPLNDSVSATFDTSVMCAKTSVSTHPDFVEDQIWLNG 259
VT A NIA++KYWGK+D L+LP N S+S T D +TSV+ DQI+ N
Sbjct: 4 VTAKAHTNIALVKYWGKKDAALMLPQNGSISLTLDH--FYTQTSVTFDEHLDTDQIYFNH 61
Query: 260 KE-ESFSNPRLQNCLREIKSRAVAEKTIAEDVLSWKVHVSSENNFPTXXXXXXXXXXXXC 436
+ + + R+ L I+ R+ + A V +EN+ PT
Sbjct: 62 QHLPTGKSARISQFLDLIRQRS-GQTNYAT--------VKTENHVPTSAGLASSASGFAA 112
Query: 437 LVSALAKLYKIK---SDVSSIARLGSGSACRSVYGGFVRWHAGSKPDGSDSIATQIADSN 607
L A ++ ++ +D+S +AR GSGSA RS++GGFV WHAG D S A + D
Sbjct: 113 LAGAASRAAGLQLDAADLSRLARRGSGSATRSIFGGFVEWHAGH--DDQSSYAEVLQDPV 170
Query: 608 HWPEMRVLVLVVGNTQKKVSSTVGM 682
W +++++ +V+ T+K +SST GM
Sbjct: 171 DW-DIQMIAVVLKATKKTISSTDGM 194
>UniRef50_Q2BIJ8 Cluster: Diphosphomevalonate decarboxylase; n=1;
Neptuniibacter caesariensis|Rep: Diphosphomevalonate
decarboxylase - Neptuniibacter caesariensis
Length = 334
Score = 103 bits (248), Expect = 4e-21
Identities = 73/242 (30%), Positives = 116/242 (47%), Gaps = 3/242 (1%)
Frame = +2
Query: 65 KMSNIVTVIAPVNIAVIKYWGKRDEKLILPLNDSVSATFDTSVMCAKTSVSTHPDFVEDQ 244
++ AP NIA+ KYWGKR+ +L LP+N S+S + + ++TS+ D DQ
Sbjct: 18 QLGTAAEAFAPSNIALCKYWGKREAELNLPINGSLSISLGE--LGSRTSI-VESDSGSDQ 74
Query: 245 IWLNGKEESFSNPRLQNCLREIKSRAVAEKTIAEDVLSWKVHVSSENNFPTXXXXXXXXX 424
++LN K L ++ ++ + L V + + NN PT
Sbjct: 75 VYLNDK--------LIEPTDRFATKVISFLNLFRRELQQPVVIKTVNNIPTAAGLASSAS 126
Query: 425 XXXCLVSALAKLYKI---KSDVSSIARLGSGSACRSVYGGFVRWHAGSKPDGSDSIATQI 595
L+ A+ Y+ +S+ AR+GSGSA RSV+ GFV W G + DG DS A ++
Sbjct: 127 GFAALMLAINDFYRFGLGNEVLSAFARMGSGSASRSVFQGFVEWQKGLREDGMDSCAQRL 186
Query: 596 ADSNHWPEMRVLVLVVGNTQKKVSSTVGMKISSETSELLKHRIQHCVPQRTERIIXAIKN 775
W R+ +L V KKV S GM+ + E++ L + + + + I AI++
Sbjct: 187 --DLEWQGFRIGLLKVATGAKKVDSRAGMQRTVESAPLYQAWPEQAA-KDLQTIKRAIED 243
Query: 776 KD 781
KD
Sbjct: 244 KD 245
>UniRef50_Q83DT5 Cluster: Diphosphomevalonate decarboxylase; n=4;
Coxiella burnetii|Rep: Diphosphomevalonate decarboxylase
- Coxiella burnetii
Length = 503
Score = 101 bits (243), Expect = 2e-20
Identities = 73/235 (31%), Positives = 114/235 (48%), Gaps = 4/235 (1%)
Frame = +2
Query: 92 APVNIAVIKYWGKRDEKLILPLNDSVSATF-DTSVMCAKTSVSTHPDFVEDQIWLNGKEE 268
AP NIA+ KYWGKR+ +L LP+ S+S + D A + ST+ + ++ +N +
Sbjct: 25 APSNIALCKYWGKRNLELNLPVTSSLSISLGDKGATAAISPSSTN----QHELIINNQPI 80
Query: 269 SFSNPRLQNCLREIKSRAVAEKTIAEDVLSWKVHVSSENNFPTXXXXXXXXXXXXCLVSA 448
+ + + L ++ A + L K H+ N P +V A
Sbjct: 81 AIYSTHAKQLLAFLE---------AFNFLGVKYHLELNFNIPLAAGLASSACAYAAIVKA 131
Query: 449 LAKLYKIKSD---VSSIARLGSGSACRSVYGGFVRWHAGSKPDGSDSIATQIADSNHWPE 619
L ++ + D +S +ARLGSGSACRSV+ GFV W+ G PDG DS A + + +WP
Sbjct: 132 LDNFFEWQLDRKSLSILARLGSGSACRSVFNGFVEWYCGKDPDGMDSYAEPLVE--NWPG 189
Query: 620 MRVLVLVVGNTQKKVSSTVGMKISSETSELLKHRIQHCVPQRTERIIXAIKNKDF 784
+ + + ++ K VSS GM+ + TS L + T+ + AI KDF
Sbjct: 190 LCIGLCILNQKPKTVSSREGMRRTVTTSPLYSAWPEKANRDLTQ-LKKAIAKKDF 243
>UniRef50_A4VT19 Cluster: Mevalonate pyrophosphate decarboxylase;
n=3; Streptococcus suis|Rep: Mevalonate pyrophosphate
decarboxylase - Streptococcus suis (strain 05ZYH33)
Length = 341
Score = 101 bits (242), Expect = 2e-20
Identities = 76/240 (31%), Positives = 114/240 (47%), Gaps = 3/240 (1%)
Frame = +2
Query: 92 APVNIAVIKYWGKRDEKLILPLNDSVSATFDTSVMCAKTSVSTHPDFVEDQIWLNGKEES 271
A NIA+IKYWGKRD++L LP+N S+S T D T V P+ D+ +LNG +
Sbjct: 10 AHTNIALIKYWGKRDKELFLPMNSSLSLTLD--AFYTDTKVVFDPELTADEFYLNGILQK 67
Query: 272 FSNPRLQNCLREIKSRAVAEKTIAEDVLSWKVHVSSENNFPTXXXXXXXXXXXXCLVSAL 451
+ ++ + E+ A V S N PT L A
Sbjct: 68 EKEILKISRFLDLFCEYIGERAFA--------RVESLNFVPTAAGLASSASAFAALALAT 119
Query: 452 AKLYKI---KSDVSSIARLGSGSACRSVYGGFVRWHAGSKPDGSDSIATQIADSNHWPEM 622
A + + +S++AR GSGS+ RS++GGFV W G+ DS+A I D++ W ++
Sbjct: 120 ATALDLDLSPATLSTLARRGSGSSTRSLFGGFVEWGMGT--GSEDSMAHPIDDAD-W-DI 175
Query: 623 RVLVLVVGNTQKKVSSTVGMKISSETSELLKHRIQHCVPQRTERIIXAIKNKDFYKFAEI 802
++VL V KK++S GM + TS ++ Q I AI ++DF K +I
Sbjct: 176 GMVVLAVNTGPKKIASREGMDHTVATSPFYTAWVE-TAKQDLVDIKAAIASRDFEKLGQI 234
>UniRef50_Q8L1I0 Cluster: Mevalonate diphosphate decarboxylase; n=1;
Paracoccus zeaxanthinifaciens|Rep: Mevalonate
diphosphate decarboxylase - Paracoccus
zeaxanthinifaciens
Length = 332
Score = 98.7 bits (235), Expect = 2e-19
Identities = 72/209 (34%), Positives = 97/209 (46%), Gaps = 3/209 (1%)
Frame = +2
Query: 92 APVNIAVIKYWGKRDEKLILPLNDSVSATFDTSVMCAKTSVSTHPDFVEDQIWLNGKEES 271
AP NIA+ KYWGKRD LPLN SVS + A T VE G +E
Sbjct: 26 APSNIALSKYWGKRDAARNLPLNSSVS------ISLANWGSHTR---VEGSG--TGHDEV 74
Query: 272 FSNPRLQNCLREIKSRAVAEKTIAEDVLSWKVHVSSENNFPTXXXXXXXXXXXXCLVSAL 451
N L + RA+A + + ++++N+ PT L AL
Sbjct: 75 HHNGTLLDPGDAFARRALAFADLFRGGRHLPLRITTQNSIPTAAGLASSASGFAALTRAL 134
Query: 452 AKLYKIK---SDVSSIARLGSGSACRSVYGGFVRWHAGSKPDGSDSIATQIADSNHWPEM 622
A + + +D+S IAR+GSGSA RS++ GFVRW+ G DG DS + WP
Sbjct: 135 AGAFGLDLDDTDLSRIARIGSGSAARSIWHGFVRWNRGEAEDGHDSHGVPL--DLRWPGF 192
Query: 623 RVLVLVVGNTQKKVSSTVGMKISSETSEL 709
R+ ++ V K SS GM + ETS L
Sbjct: 193 RIAIVAVDKGPKPFSSRDGMNHTVETSPL 221
>UniRef50_Q23R64 Cluster: Diphosphomevalonate decarboxylase family
protein; n=1; Tetrahymena thermophila SB210|Rep:
Diphosphomevalonate decarboxylase family protein -
Tetrahymena thermophila SB210
Length = 432
Score = 98.7 bits (235), Expect = 2e-19
Identities = 83/282 (29%), Positives = 129/282 (45%), Gaps = 48/282 (17%)
Frame = +2
Query: 101 NIAVIKYWGKRDEKLILPLNDSVSATFDTSVMCAKTSVSTHPDFVEDQIWLNGKEESFSN 280
NIA++KYWGK DE+ ILPLN S T T + +T+++ + + + LNG+ S
Sbjct: 20 NIALVKYWGKFDEEYILPLNSSTGITLSTEDLQTRTTITLTNKYKDIKFLLNGQPHPVSG 79
Query: 281 PRLQNCLREIKSRAVA------------------EKTIAE----DVLSWKVHVSSENNFP 394
RL+ L+ + +A+A KT+ E D+ K+ + S N+FP
Sbjct: 80 -RLKKILKFFEDKALAALGEELVPLQEGESQDTKRKTLKEFLNGDLSQLKLKIKSVNSFP 138
Query: 395 TXXXXXXXXXXXXCLVSALAKLYKIKSDV----SSIARLGSGSACRSVYGGFVRW----- 547
T L L +Y +K + S IARLGSGSA RS+YGG V W
Sbjct: 139 TASGLASSASGLAALSVCLFDVYHMKEEYEFQRSVIARLGSGSASRSIYGGLVEWTGVPH 198
Query: 548 -HAGSKPDGSDS----------------IATQIADSNHWPEMRVLVLVVGNTQKKVSSTV 676
+ K + ++ IA Q + + ++ V V+ K+V ST
Sbjct: 199 QYLQKKFESKNNEIQLSEQEYEQLSKLCIAKQTHNETFFEDLDVFVVAYSFESKEVPSTS 258
Query: 677 GMKISSETSELLKHRIQHCVPQRTERIIXAIKNKDFYKFAEI 802
GM S++TSELLK+R + + AI+ K++ + A +
Sbjct: 259 GMLQSTQTSELLKYRALNTAHVHIAGVKKAIEEKNYNELARL 300
>UniRef50_A5EVP2 Cluster: Diphosphomevalonate decarboxylase; n=1;
Dichelobacter nodosus VCS1703A|Rep: Diphosphomevalonate
decarboxylase - Dichelobacter nodosus (strain VCS1703A)
Length = 328
Score = 97.9 bits (233), Expect = 3e-19
Identities = 72/242 (29%), Positives = 111/242 (45%), Gaps = 3/242 (1%)
Frame = +2
Query: 83 TVIAPVNIAVIKYWGKRDEKLILPLNDSVSATFDTSVMCAKTSVSTHPDFVEDQIWLNGK 262
T AP NIA+ KYWGKRD +L LP N S+S + + + T++S DQ++ + +
Sbjct: 5 TAFAPANIALAKYWGKRDAQLNLPTNGSLSISL--AHLGTTTTISAGE---RDQLYCDHR 59
Query: 263 EESFSNPRLQNCLREIKSRAVAEKTIAEDVLSWKVHVSSENNFPTXXXXXXXXXXXXCLV 442
+Q I + + ++NN PT L
Sbjct: 60 LLPPDTAFVQKVWHFIDFCQPKRPPLV---------IHTQNNIPTAAGLASSASGFAALT 110
Query: 443 SALAKLYK---IKSDVSSIARLGSGSACRSVYGGFVRWHAGSKPDGSDSIATQIADSNHW 613
AL ++ + +S IAR GSGSACRS++ GFV W G K DGSD A IA + W
Sbjct: 111 LALNDFFQWSLSREQLSQIARRGSGSACRSLWQGFVYWQKGEKADGSDCYARPIA--SDW 168
Query: 614 PEMRVLVLVVGNTQKKVSSTVGMKISSETSELLKHRIQHCVPQRTERIIXAIKNKDFYKF 793
++R+ ++ + KK+SS M ++ +S L Q + I A+ ++DF
Sbjct: 169 QDLRLGIITIDAAAKKISSRQAMNHTAASSPLFSSWTQ-AAEADLKVIYQAVLDRDFLTL 227
Query: 794 AE 799
A+
Sbjct: 228 AQ 229
>UniRef50_Q04EX2 Cluster: Mevalonate pyrophosphate decarboxylase;
n=2; Oenococcus oeni|Rep: Mevalonate pyrophosphate
decarboxylase - Oenococcus oeni (strain BAA-331 / PSU-1)
Length = 314
Score = 94.7 bits (225), Expect = 3e-18
Identities = 68/205 (33%), Positives = 100/205 (48%), Gaps = 3/205 (1%)
Frame = +2
Query: 86 VIAPVNIAVIKYWGKRDEKLILPLNDSVSATFDTSVMCAKTSVSTHPDFVEDQIWLNGKE 265
V A NIA+IKYWGK D LP + S+ T D TSV +D LNG++
Sbjct: 4 VRAYTNIALIKYWGKSDLNWNLPTSSSIGLTLDR--FYTDTSVEIDQFSKKDFFQLNGQQ 61
Query: 266 ESFSNPRLQNCLREIKSRAVAEKTIAEDVLSWKVHVSSENNFPTXXXXXXXXXXXXCLVS 445
P++ + I++ + K V V SEN+ PT L
Sbjct: 62 --IEGPKISKIINFIRN-SCGNKNF--------VKVISENHVPTSAGLASSASAFAALTK 110
Query: 446 ALAKLYKIKSD---VSSIARLGSGSACRSVYGGFVRWHAGSKPDGSDSIATQIADSNHWP 616
A + + ++ D +S IAR+GSGSA RS++GGF WH G D DS A I D +
Sbjct: 111 AANQAFGLELDNRELSKIARIGSGSASRSIFGGFSIWHKGQNKD--DSFAESILDPVDF- 167
Query: 617 EMRVLVLVVGNTQKKVSSTVGMKIS 691
++RV+ ++ KK+SS+ GM+++
Sbjct: 168 DIRVIDILADKRVKKISSSQGMQLA 192
>UniRef50_A7KGY8 Cluster: NapT5; n=2; Streptomyces|Rep: NapT5 -
Streptomyces aculeolatus
Length = 378
Score = 94.3 bits (224), Expect = 4e-18
Identities = 75/215 (34%), Positives = 103/215 (47%), Gaps = 8/215 (3%)
Frame = +2
Query: 89 IAPVNIAVIKYWGKRDEKLILPLNDSVSATFDTSVMCAKTSVSTHPDFVEDQIWLNGKEE 268
+A NIA+IKYWGKRDE L+LP DS+S T D + T V P+ D + L G+
Sbjct: 51 VAHPNIALIKYWGKRDEHLVLPRTDSLSMTLD--IFPTTTRVRLAPEAGRDVVVLGGR-- 106
Query: 269 SFSNPRLQNCLREIKSRAVAEKTIAEDVLSWKVHVSSENNFPTXXXXXXXXXXXXCLVSA 448
P LR I + + A + + V S N PT L A
Sbjct: 107 ----PAEGEALRRIVTFLDLVRHSAR--VPHRAVVESHNTVPTGAGLASSASGFAALAVA 160
Query: 449 LAKLYKIK---SDVSSIARLGSGSACRSVYGGFVRWHAGSKPDGSDSIATQIAD-SNHWP 616
A+ Y + + +S +AR GSGSA RSV+GGF WHAG +P G D+ A + + P
Sbjct: 161 AARAYGLSLTATGLSRLARRGSGSASRSVFGGFAVWHAG-RP-GQDTKAADLGSYAEPVP 218
Query: 617 ----EMRVLVLVVGNTQKKVSSTVGMKISSETSEL 709
+ ++V VV K VSS M+ + +TS L
Sbjct: 219 VADLDPALVVAVVDAGPKAVSSRAAMRRTVDTSPL 253
>UniRef50_Q5KSN1 Cluster: Mevalonate diphosphate decarboxylase; n=7;
Actinomycetales|Rep: Mevalonate diphosphate
decarboxylase - Streptomyces sp. KO-3988
Length = 350
Score = 93.9 bits (223), Expect = 5e-18
Identities = 72/223 (32%), Positives = 105/223 (47%), Gaps = 8/223 (3%)
Frame = +2
Query: 71 SNIVTVIAPVNIAVIKYWGKRDEKLILPLNDSVSATFDTSVMCAKTSVSTHPDFVEDQIW 250
+N VT +A NIA+IKYWGKRDE L LP S+S T D + T V + +D++
Sbjct: 17 ANGVTAVAQPNIALIKYWGKRDEHLFLPWTSSLSMTLD--IFPTTTRVHLDAEATDDEVT 74
Query: 251 LNGKEES-FSNPRLQNCLREIKSRAVAEKTIAEDVLSWKVHVSSENNFPTXXXXXXXXXX 427
NG + R+ L ++ RA L+ + V + N PT
Sbjct: 75 FNGAPAAGEERRRITGFLDLVRQRA---------GLTHRAVVDTRNTVPTGAGLASSAGG 125
Query: 428 XXCLVSALAKLYKIKSD---VSSIARLGSGSACRSVYGGFVRWHAGSKPDGSDSIATQIA 598
L A A Y + D +S +AR GSGSA RS++GGF W+AG+ P + A +
Sbjct: 126 FAALAVAAATAYGLDLDDTGLSRLARRGSGSASRSIFGGFAVWNAGT-PTAPPAEADLSS 184
Query: 599 DSNHWP----EMRVLVLVVGNTQKKVSSTVGMKISSETSELLK 715
+ P + +++ VV K VSS M+ + ETS L +
Sbjct: 185 YAEPVPVGDLDPALVIAVVNAGPKDVSSRAAMRRTVETSPLFE 227
>UniRef50_Q038V4 Cluster: Mevalonate pyrophosphate decarboxylase;
n=1; Lactobacillus casei ATCC 334|Rep: Mevalonate
pyrophosphate decarboxylase - Lactobacillus casei
(strain ATCC 334)
Length = 334
Score = 93.9 bits (223), Expect = 5e-18
Identities = 69/207 (33%), Positives = 102/207 (49%), Gaps = 3/207 (1%)
Frame = +2
Query: 92 APVNIAVIKYWGKRDEKLILPLNDSVSATFDTSVMCAKTSVSTHPDFVEDQIWLNGKEES 271
A NIA+IKYWGK + KL+LP S+S T + T+V+ P +D+ LNG+E+
Sbjct: 7 AHTNIALIKYWGKANRKLMLPATSSISLTLND--FYTDTAVTFDPSLNDDRFMLNGEEQ- 63
Query: 272 FSNPRLQNCLREIKSRAVAEKTIAEDVLSWKVHVSSENNFPTXXXXXXXXXXXXCLVSAL 451
NP + ++ +S V+S N+ PT L +A
Sbjct: 64 --NP--------VAVSRFLDRVRHLGKISTYAQVTSLNHVPTAAGLASSASAFAALATAA 113
Query: 452 AK---LYKIKSDVSSIARLGSGSACRSVYGGFVRWHAGSKPDGSDSIATQIADSNHWPEM 622
++ L +++S +AR GSGSA RS++GG V WH G D + S A +A P +
Sbjct: 114 SRAAGLNLSPTELSRLARRGSGSATRSIFGGAVIWHRGH--DDASSFAEPLAIQPSLP-L 170
Query: 623 RVLVLVVGNTQKKVSSTVGMKISSETS 703
R+LV+ V +K VSS GM + TS
Sbjct: 171 RMLVVTVSAEKKAVSSRKGMANTVATS 197
>UniRef50_Q31EU7 Cluster: Diphosphomevalonate decarboxylase; n=1;
Thiomicrospira crunogena XCL-2|Rep: Diphosphomevalonate
decarboxylase - Thiomicrospira crunogena (strain XCL-2)
Length = 332
Score = 88.6 bits (210), Expect = 2e-16
Identities = 73/239 (30%), Positives = 113/239 (47%), Gaps = 3/239 (1%)
Frame = +2
Query: 92 APVNIAVIKYWGKRDEKLILPLNDSVSATFDTSVMCAKTSVSTHPDFVEDQIWLNGKEES 271
APVNIA+ KYWGKR+ L LP N S+S + + KT + + D I+LN + +
Sbjct: 26 APVNIALSKYWGKRNVDLNLPTNSSLSISLPG--LGTKTQIEWVEN-QSDHIYLNETKVA 82
Query: 272 FSNPRLQNCLREIKSRAVAEKTIAEDVLSWKVHVSSENNFPTXXXXXXXXXXXXCLVSAL 451
+ Q + R + + V++ N+ PT LV AL
Sbjct: 83 SDDSFAQ------RIRLFLD--LFRPNTQGGFIVNTLNSVPTAAGLASSASGYAALVLAL 134
Query: 452 AKLYKIK---SDVSSIARLGSGSACRSVYGGFVRWHAGSKPDGSDSIATQIADSNHWPEM 622
++ +S +ARLGSGSA RS+Y GF WH G +G DS A +I + WPE+
Sbjct: 135 NDCFQWDLPLKRLSLLARLGSGSASRSLYDGFALWHKGQLDNGMDSYAEKIDQA--WPEL 192
Query: 623 RVLVLVVGNTQKKVSSTVGMKISSETSELLKHRIQHCVPQRTERIIXAIKNKDFYKFAE 799
+ +L + + K +SST GM+ + EL + ++ AI++KDF + +
Sbjct: 193 CIGLLEIDVSTKPISSTQGMQNTVNHCELYQAWPDKAEAD-LQKTHQAIQDKDFQQLGQ 250
>UniRef50_Q660I4 Cluster: Mevalonate pyrophosphate decarboxylase;
n=3; Borrelia burgdorferi group|Rep: Mevalonate
pyrophosphate decarboxylase - Borrelia garinii
Length = 312
Score = 88.2 bits (209), Expect = 2e-16
Identities = 59/198 (29%), Positives = 101/198 (51%), Gaps = 2/198 (1%)
Frame = +2
Query: 101 NIAVIKYWGKRDEKLILPLNDSVSATFDTSVMCAKTSVSTHPDFVEDQIWLNGKEESFSN 280
++A+IKYWGK+D L +P S++ + D ++ +S +D+I LN K F N
Sbjct: 10 SLALIKYWGKKDAFLNIPATSSLAVSVDKFYSISELELSD-----QDEIILNSKPVVFQN 64
Query: 281 PRLQNCLREIKSRAVAEKTIAEDVLSWKVHVSSENNFPTXXXXXXXXXXXXCLVSALAKL 460
RE A + ++E + +K+ SENNFPT + + + K
Sbjct: 65 -------REKVFFDYARQILSEPNVRFKI--KSENNFPTAAGLASSSSGFASIAACILKY 115
Query: 461 YKIKS--DVSSIARLGSGSACRSVYGGFVRWHAGSKPDGSDSIATQIADSNHWPEMRVLV 634
+ S S++AR+GS SA R+VYGGF GSK + Q+ D +++ ++R++
Sbjct: 116 FNKYSFNSASNLARVGSASAARAVYGGFTILKEGSKE------SFQLRDQSYFNDLRIIF 169
Query: 635 LVVGNTQKKVSSTVGMKI 688
++ + +K++SS V M I
Sbjct: 170 AIIDSNEKELSSRVAMNI 187
>UniRef50_A2RID5 Cluster: Diphosphomevalonate decarboxylase; n=4;
Lactobacillales|Rep: Diphosphomevalonate decarboxylase -
Lactococcus lactis subsp. cremoris (strain MG1363)
Length = 318
Score = 86.6 bits (205), Expect = 7e-16
Identities = 70/211 (33%), Positives = 99/211 (46%), Gaps = 3/211 (1%)
Frame = +2
Query: 68 MSNIVTVIAPVNIAVIKYWGKRDEKLILPLNDSVSATFDTSVMCAKTSVSTHPDFVEDQI 247
M NIVT A NIA+IKYWGK D L +P S+S T + TSV D D +
Sbjct: 1 MKNIVTARAHTNIALIKYWGKTDIALNIPTTSSLSMTLEP--FYTTTSVE-FTDNESDSL 57
Query: 248 WLNGKEESFSNPRLQNCLREIKSRAVAEKTIAEDVLSWKVHVSSENNFPTXXXXXXXXXX 427
LN E S R+ L ++ + KV + SEN+ PT
Sbjct: 58 ILNSAMEDSS--RVSKFLEMMRGQYGNFP---------KVMIQSENHVPTAAGLASSASS 106
Query: 428 XXCLVSA---LAKLYKIKSDVSSIARLGSGSACRSVYGGFVRWHAGSKPDGSDSIATQIA 598
L +A L L K S++S IAR GSGSA RS++G F W+ G S + +
Sbjct: 107 FAALTAAMFGLLDLEKDDSEMSRIARRGSGSASRSIFGNFAVWNKGENHQSSFAESFYNK 166
Query: 599 DSNHWPEMRVLVLVVGNTQKKVSSTVGMKIS 691
D + ++V + + +KK+SST GM+++
Sbjct: 167 DIG----LSMIVAEISSEKKKMSSTKGMQLA 193
>UniRef50_Q97SI0 Cluster: Diphosphomevalonate decarboxylase; n=39;
Streptococcus|Rep: Diphosphomevalonate decarboxylase -
Streptococcus pneumoniae
Length = 317
Score = 86.2 bits (204), Expect = 9e-16
Identities = 68/252 (26%), Positives = 117/252 (46%), Gaps = 4/252 (1%)
Frame = +2
Query: 80 VTVIAPVNIAVIKYWGKRDEKLILPLNDSVSATFDTSVMCAKTSVSTHP-DFVEDQIWLN 256
VTV + NIA+IKYWGK+ EK ++P S+S T + M +T++S P + D+ ++N
Sbjct: 6 VTVRSYANIAIIKYWGKKKEKEMVPATSSISLTLEN--MYTETTLSPLPANVTADEFYIN 63
Query: 257 GKEESFSNPRLQNCLREIKSRAVAEKTIAEDVLSWKVHVSSENNFPTXXXXXXXXXXXXC 436
G +LQN + K + ++ V + ++NN PT
Sbjct: 64 G--------QLQNEVEHAKMSKIIDR--YRPAGEGFVRIDTQNNMPTAAGLSSSSSGLSA 113
Query: 437 LVSALAKLYKI---KSDVSSIARLGSGSACRSVYGGFVRWHAGSKPDGSDSIATQIADSN 607
LV A +K+ +S ++ A+ SGS+ RS YG W D + +I
Sbjct: 114 LVKACNAYFKLGLDRSQLAQEAKFASGSSSRSFYGPLGAW---------DKDSGEIYPVE 164
Query: 608 HWPEMRVLVLVVGNTQKKVSSTVGMKISSETSELLKHRIQHCVPQRTERIIXAIKNKDFY 787
++ +++LV+ + +K +SS GMK+ ETS ++ + +I +K DF
Sbjct: 165 TDLKLAMIMLVLEDKKKPISSRDGMKLCVETSTTFDDWVRQSEKDYQDMLIY-LKENDFA 223
Query: 788 KFAEIQ*KTVIS 823
K E+ K ++
Sbjct: 224 KIGELTEKNALA 235
>UniRef50_Q5AB67 Cluster: Putative uncharacterized protein; n=1;
Candida albicans|Rep: Putative uncharacterized protein -
Candida albicans (Yeast)
Length = 177
Score = 84.2 bits (199), Expect = 4e-15
Identities = 67/168 (39%), Positives = 77/168 (45%), Gaps = 4/168 (2%)
Frame = -3
Query: 798 SANL*KSLFFIAXIIRSVLWGTQCCIRCFNNSDVSEDIFIPTVELTFF*VLPTTSTKTRI 619
SAN KSL IA + S LWGT IR N S+V+ IP V F TT
Sbjct: 4 SANFGKSLSRIAFFMASNLWGTTSAIRWANKSEVATVDCIPVVSGVSFLSSSTTKMTASS 63
Query: 618 SGQ*FESAICVAIESLPSGFEPACHLTKPP*TLLHALPEPNLAIELTSDLI---LYNFAK 448
GQ AI A ES PSG P T PP + HA PEP AI SD+ YNFA
Sbjct: 64 DGQCSNGAISTAFESCPSGKVPISQATNPPKSDSHAEPEPLRAIFDNSDMSWGNSYNFAI 123
Query: 447 ADTKQXXXXXXXXXXXAVGKLFSEET*TF-HDSTSSAIVFSATARDFI 307
A+T AVGKLFSE F D+ + S AR+F+
Sbjct: 124 AETNAAKPAADDAKPAAVGKLFSETMCNFICDNLGVSGDCSIEARNFL 171
>UniRef50_A6G139 Cluster: Mevalonate diphosphate decarboxylase; n=1;
Plesiocystis pacifica SIR-1|Rep: Mevalonate diphosphate
decarboxylase - Plesiocystis pacifica SIR-1
Length = 344
Score = 74.1 bits (174), Expect = 4e-12
Identities = 70/217 (32%), Positives = 99/217 (45%), Gaps = 12/217 (5%)
Frame = +2
Query: 89 IAPVNIAVIKYWGKR---DEKLILPLNDSVSATFDTSVMCAKTSVSTHPDFVEDQIWLNG 259
+A NIA++KYWGKR D L LP S+S T + T+V+ P D+ L+G
Sbjct: 10 VAHSNIALVKYWGKRAGVDPALNLPAVGSLSMTLGE--LRTDTTVAPAPAGGSDRFELDG 67
Query: 260 KEESFSNPRLQNCLREIKSRAVAEKTIAEDVLSWKVHVSSENNFPTXXXXXXXXXXXXCL 439
P + + A+A A V+S N+ PT L
Sbjct: 68 ALVE-GKPAAKVFAHLDRLHALAGLEGARPACV----VTSINHLPTAAGLASSASGFAAL 122
Query: 440 VSALAKLYKI--------KSDVSSIARLGSGSACRSVYGGFVRWHAGSKPDGSDSIATQI 595
A A Y + ++ +S +R GSGSA RS++G FVR AG+ DGSD IA +
Sbjct: 123 TVAAAGAYGLYDSLDGAARTRLSGWSRQGSGSAARSLWGAFVRLDAGAAEDGSDCIARPL 182
Query: 596 -ADSNHWPEMRVLVLVVGNTQKKVSSTVGMKISSETS 703
+ ++R+LV+ KKV ST GM+ S TS
Sbjct: 183 EVPAALAADLRLLVVHTARGAKKVGSTGGMESSRLTS 219
>UniRef50_Q6XYE3 Cluster: FP17780; n=2; Homo sapiens|Rep: FP17780 -
Homo sapiens (Human)
Length = 140
Score = 74.1 bits (174), Expect = 4e-12
Identities = 34/63 (53%), Positives = 44/63 (69%)
Frame = +2
Query: 554 GSKPDGSDSIATQIADSNHWPEMRVLVLVVGNTQKKVSSTVGMKISSETSELLKHRIQHC 733
G + DG DSIA Q+A +HWPE+RVL+LVV +K STVGM+ S ETS LL+ R +
Sbjct: 2 GEQADGKDSIARQVAPESHWPELRVLILVVSAEKKLTGSTVGMRASVETSPLLRFRAESV 61
Query: 734 VPQ 742
VP+
Sbjct: 62 VPR 64
>UniRef50_A0M7H5 Cluster: Diphosphomevalonate decarboxylase; n=15;
Bacteria|Rep: Diphosphomevalonate decarboxylase -
Gramella forsetii (strain KT0803)
Length = 380
Score = 71.7 bits (168), Expect = 2e-11
Identities = 67/259 (25%), Positives = 108/259 (41%), Gaps = 15/259 (5%)
Frame = +2
Query: 92 APVNIAVIKYWGKRDEKLILPLNDSVSATFD--TSVMCAKTSVSTHPDFVEDQIWLNGKE 265
+P NIA+IKYWGK + + +P N S+S T D S K +P + + GKE
Sbjct: 44 SPSNIALIKYWGKLENQ--IPANPSISFTLDHCKSTTTLKFKKKENPGNFDFDFFFEGKE 101
Query: 266 ESFSNPRLQNCLREIKSRAVAEKTIAEDVLSWKVHVSSENNFPTXXXXXXXXXXXXCLVS 445
+ P+++ I++ K + + SEN+FP L
Sbjct: 102 KEDFKPKIRKFFERIEAYCPYLK-------DYYFEIHSENSFPHSSGIASSASGMSALAL 154
Query: 446 ALAKLYK----------IKSDVSSIARLGSGSACRSVYGGFVRWHAGSK-PDGSDSIATQ 592
L +L K S +ARLGSGSA RS+ G V W SD A +
Sbjct: 155 CLMQLEKELNPKIDKEQFNRKASFLARLGSGSASRSIAGELVVWGKHEYIESSSDLYAIE 214
Query: 593 IADSNH--WPEMRVLVLVVGNTQKKVSSTVGMKISSETSELLKHRIQHCVPQRTERIIXA 766
H + + +L+V +K+VSST+G + + R + + +++I
Sbjct: 215 YPHQVHKNFKNYQDTILLVDKGEKQVSSTIGHDL-MHGHPFAEKRFEQ-ANENLKKLIPV 272
Query: 767 IKNKDFYKFAEIQ*KTVIS 823
+K+ D F +I + +S
Sbjct: 273 LKSGDLSAFIKIVEREALS 291
>UniRef50_Q8SRR7 Cluster: MEVALONATE PYROPHOSPHATE DECARBOXYLASE;
n=1; Encephalitozoon cuniculi|Rep: MEVALONATE
PYROPHOSPHATE DECARBOXYLASE - Encephalitozoon cuniculi
Length = 303
Score = 71.3 bits (167), Expect = 3e-11
Identities = 65/237 (27%), Positives = 108/237 (45%), Gaps = 3/237 (1%)
Frame = +2
Query: 101 NIAVIKYWGKRDEKLILPLNDSVSATFDTSVMCAKTSVSTHPDFVEDQIWLNGKEESFSN 280
NIAVIKYWGK D +P + S+S F + +T V H ED+ +LNGK
Sbjct: 14 NIAVIKYWGKADTINNMPSSRSIS--FPLTNFLTETVVE-H-SLEEDRFYLNGKMLPIGE 69
Query: 281 PRLQNCLREIKSRAVAEKTIAEDVLSWKVHVSSENNFPTXXXXXXXXXXXXCLVSALAKL 460
++ + + ++ ++ + + S +NFP LV AL
Sbjct: 70 -KMGRAVEIFRKKSGDDRPVC---------IRSFSNFPHSCGLASSASGLAALVLALNDF 119
Query: 461 YKI---KSDVSSIARLGSGSACRSVYGGFVRWHAGSKPDGSDSIATQIADSNHWPEMRVL 631
Y + + ++ AR+GSGSA RS+ G + D ++ + S W E+R+L
Sbjct: 120 YGLDMPEEELCIAARIGSGSAGRSISTGIHLF---------DGMSVERLPS--WKEVRIL 168
Query: 632 VLVVGNTQKKVSSTVGMKISSETSELLKHRIQHCVPQRTERIIXAIKNKDFYKFAEI 802
+++ KK ST GM + ETS + R+ + ++ + ++ I KDF FA +
Sbjct: 169 SIILSGDCKKTGSTEGMIRTKETSNFYQERLAR-IERKIKAMVQYISQKDFDGFAHL 224
>UniRef50_Q7QXZ9 Cluster: GLP_479_14176_13169; n=1; Giardia lamblia
ATCC 50803|Rep: GLP_479_14176_13169 - Giardia lamblia
ATCC 50803
Length = 335
Score = 68.1 bits (159), Expect = 3e-10
Identities = 68/256 (26%), Positives = 107/256 (41%), Gaps = 18/256 (7%)
Frame = +2
Query: 89 IAPVNIAVIKYWGKRDEKLILPLNDSVSATFDTSVMCAKTSVSTHP---DFVEDQIWLNG 259
IA N+A+IKYWGK D+K P + S+S T + AKT V + + + +NG
Sbjct: 4 IAAPNVALIKYWGKGDQKTNSPASGSISFTLSAETLWAKTKVLSRDVSKGTIGPTMEING 63
Query: 260 KEESFSNP--RLQNCLREIKSRAVAEKTIAEDVL------SWKVHVSSENNFPTXXXXXX 415
+ + RL + + A + L S + + S+ N P
Sbjct: 64 TTVAVKDSLVRLLDGFSQCAHLTGASASSGSSALGLVEEFSRDISIVSQTNIPIASGIAS 123
Query: 416 XXXXXXCLVSALAKLYKIKSD---VSSIARLGSGSACRSVYGGFVRWHAGSKPDGS---D 577
L AL + Y+ D +S +ARL SGS RSVY G V +
Sbjct: 124 SAAGAAALALALNEYYRTNFDRKILSCLARLYSGSGARSVYPGAVEMVCDANAHSLLRWH 183
Query: 578 SIATQIADSNHWPEMRVLVLVVGNTQKKVSSTVGM-KISSETSELLKHRIQHCVPQRTER 754
++ + S H + L+L+ + K +SST M K + S+ K R+ +P R +R
Sbjct: 184 AVPLSVHPSFH--SLECLILLFSSAPKPLSSTEAMNKCADHPSQ--KARLVR-IPARLDR 238
Query: 755 IIXAIKNKDFYKFAEI 802
A++ F AE+
Sbjct: 239 CRSALQRGCFNDLAEV 254
>UniRef50_Q9HRQ4 Cluster: Diphosphomevalonate decarboxylase; n=10;
Halobacteriaceae|Rep: Diphosphomevalonate decarboxylase
- Halobacterium salinarium (Halobacterium halobium)
Length = 334
Score = 60.5 bits (140), Expect = 5e-08
Identities = 62/234 (26%), Positives = 99/234 (42%), Gaps = 4/234 (1%)
Frame = +2
Query: 110 VIKYWGKRDEKLILPLNDSVSATFDTSVMCAKTSVSTHPDFVEDQIWLNGKEES-FSNPR 286
++KY G RDE L +P +DS+S T+ T+V PD DQ ++G + R
Sbjct: 22 LVKYHGMRDESLRMPYHDSISVC--TAPSNTTTTVEFDPDRDADQYVVDGDTVTGHGADR 79
Query: 287 LQNCLREIKSRAVAEKTIAEDVLSWKVHVSSENNFPTXXXXXXXXXXXXCLVSALAKLYK 466
+++ + ++ RA + +V + S+N+FPT A +
Sbjct: 80 IRSVVDAVRDRAGFDH---------RVRLESQNSFPTNIGLGSSSSGFAAAALACVRAAG 130
Query: 467 IKSD---VSSIARLGSGSACRSVYGGFVRWHAGSKPDGSDSIATQIADSNHWPEMRVLVL 637
+ D VS++AR GS SA R+V GGF HAG D A + ++R+
Sbjct: 131 LDLDLPTVSTVARRGSASAARAVTGGFSDLHAGLN-DADCRSERLDAPAEFASDLRI--- 186
Query: 638 VVGNTQKKVSSTVGMKISSETSELLKHRIQHCVPQRTERIIXAIKNKDFYKFAE 799
VVG T + S + R+ H Q E + A++ DF + E
Sbjct: 187 VVGEV-PAYKETESAHAEAADSHMFDARLAHVQGQLAE-MRDAVRAGDFQRVFE 238
>UniRef50_Q5ZTW8 Cluster: Mevalonate diphosphate decarboxylase; n=4;
Legionella pneumophila|Rep: Mevalonate diphosphate
decarboxylase - Legionella pneumophila subsp.
pneumophila (strain Philadelphia 1 /ATCC 33152 / DSM
7513)
Length = 322
Score = 58.8 bits (136), Expect = 2e-07
Identities = 61/247 (24%), Positives = 103/247 (41%), Gaps = 10/247 (4%)
Frame = +2
Query: 92 APVNIAVIKYWGKRDEKLILPLNDSVSATFDTSVMCAKTSVSTHPDFVEDQIWLNGKEES 271
AP NIA+IKY GK+DE LP N S+S T + K + + + + G E
Sbjct: 14 APANIALIKYMGKKDENSNLPDNSSLSYTLSNLLSSVKLEKLPTKKDIWEPLTIPGAPEF 73
Query: 272 FSNPRLQNCLREIKSRAVAEKTIAEDVLSW--KVHVSSENNFP----TXXXXXXXXXXXX 433
N E + R + ++ + + S NNFP
Sbjct: 74 -------NLSVEAQKRFIDHLVRLKEYFGYVGGFLIQSSNNFPHSSGLASSASSFAALTK 126
Query: 434 CLVSALAKLYKIK----SDVSSIARLGSGSACRSVYGGFVRWHAGSKPDGSDSIATQIAD 601
C AL++L + + + ++RLGSGS+CRS Y + W G K D
Sbjct: 127 CASIALSELTQKPLPSIDEQAQLSRLGSGSSCRSFYAPWALW-TGDKVSAIDL------- 178
Query: 602 SNHWPEMRVLVLVVGNTQKKVSSTVGMKISSETSELLKHRIQHCVPQRTERIIXAIKNKD 781
+ ++ V+V+ + +K++ S V K+ +TS + R + + ++ A +NKD
Sbjct: 179 --PYKDLLHQVIVISSQEKEIPSRVAHKL-VKTSPFYETRSER-AEANLKLLLNAFENKD 234
Query: 782 FYKFAEI 802
+ +I
Sbjct: 235 WTSIYQI 241
>UniRef50_A4GKI0 Cluster: Cytosolic mevalonate-5-diphosphate
decarboxylase; n=1; Cyanophora paradoxa|Rep: Cytosolic
mevalonate-5-diphosphate decarboxylase - Cyanophora
paradoxa
Length = 100
Score = 57.6 bits (133), Expect = 4e-07
Identities = 28/70 (40%), Positives = 41/70 (58%), Gaps = 5/70 (7%)
Frame = +2
Query: 128 KRDEKLILPLNDSVSATFDTSVMCAKTSVSTHPDFVEDQIWLNGKEESFSN-----PRLQ 292
KRD KLILP+N S+SAT D + + T+V+ + D++WLNGKE RL+
Sbjct: 1 KRDSKLILPVNSSLSATLDQADLMTHTTVTASKGYERDRMWLNGKEHDIDGNEETAMRLR 60
Query: 293 NCLREIKSRA 322
C+ ++ RA
Sbjct: 61 RCIAALRERA 70
>UniRef50_Q6MMJ9 Cluster: Diphosphomevalonate decarboxylase; n=1;
Bdellovibrio bacteriovorus|Rep: Diphosphomevalonate
decarboxylase - Bdellovibrio bacteriovorus
Length = 326
Score = 54.8 bits (126), Expect = 3e-06
Identities = 58/215 (26%), Positives = 99/215 (46%), Gaps = 12/215 (5%)
Frame = +2
Query: 80 VTVIAPVNIAVIKYWGKRDEKLILPLNDSVSATFDTSVMCAKTSVS-THPDFVEDQIWLN 256
VTV AP NIA+IKY GK + P N S+S T + +T V T D +DQ W
Sbjct: 4 VTVSAPSNIALIKYMGKIEGSGNKPTNGSLSYTLEN----LRTYVRLTEVDGAQDQ-WKP 58
Query: 257 GKEESFSNPRLQNCLREIKSRAVAEKTIAEDVLSWKVH--VSSENNFPTXXXXXXXXXXX 430
E L + + R + +D K + S NNFP+
Sbjct: 59 LVREDLQKIELS---EKGQQRFIKHLQNLKDKWGIKQSFLIESANNFPSDCGLASSASSF 115
Query: 431 XCLVSALAKLYK---------IKSDVSSIARLGSGSACRSVYGGFVRWHAGSKPDGSDSI 583
L A A++++ K +S ++R GSGS+CRS++ + W + + ++ +
Sbjct: 116 AALTLAAAEMFQQINPQPWGTDKKYLSELSRQGSGSSCRSLFTPWALW----QHEYAEPM 171
Query: 584 ATQIADSNHWPEMRVLVLVVGNTQKKVSSTVGMKI 688
A ++ + +H +V++V +++K+VSS+ K+
Sbjct: 172 AFEVKNLHH------MVVIVEDSKKEVSSSEAHKL 200
>UniRef50_A5V173 Cluster: GHMP kinase, C terminal domain protein;
n=4; Chloroflexaceae|Rep: GHMP kinase, C terminal domain
protein - Roseiflexus sp. RS-1
Length = 376
Score = 45.6 bits (103), Expect = 0.002
Identities = 51/199 (25%), Positives = 83/199 (41%), Gaps = 6/199 (3%)
Frame = +2
Query: 65 KMSNIVTVIAPVNIAVIKYWGKRDEKLILPLNDSVSATFDTSVMCAKTSVSTHPDFVEDQ 244
++ + +A V+KY G D K + S+S D T V PD +D
Sbjct: 30 RVRGVAAALAYPMQGVLKYHGLSDWKYRIAFLPSISLCNDAGHTL--TLVEFDPDLPDDS 87
Query: 245 IWLNGKEESFSN-PRLQNCLREIKSRAVAEKTIAEDVLSWKVHVSSENNFPTXXXXXXXX 421
+NG+ R+Q L I RAV+ T+ V S +V+ F
Sbjct: 88 ATINGQPARGRELERVQQSLDAI--RAVSGATVHARVTSR--NVTRGTRFGKGLGSSASA 143
Query: 422 XXXXCLVSALAKLYKIKSD-----VSSIARLGSGSACRSVYGGFVRWHAGSKPDGSDSIA 586
L +A+A LY ++ VS +ARL +GS CRS GG W + +S A
Sbjct: 144 SAALAL-AAIAALYGEEAASNRRLVSCMARLLAGSGCRSAAGGCSIWLSYPGIAHEESFA 202
Query: 587 TQIADSNHWPEMRVLVLVV 643
++ D+ ++R++ + +
Sbjct: 203 VRLDDAGQLDDVRLITVPI 221
>UniRef50_Q12FN4 Cluster: Binding-protein-dependent transport
systems inner membrane component; n=13;
Proteobacteria|Rep: Binding-protein-dependent transport
systems inner membrane component - Polaromonas sp.
(strain JS666 / ATCC BAA-500)
Length = 336
Score = 34.7 bits (76), Expect = 3.0
Identities = 18/46 (39%), Positives = 26/46 (56%), Gaps = 1/46 (2%)
Frame = -1
Query: 620 FQANDSNLQFVWL*-NRYHQVLSQHATLQNLRKHFYMHCLSLILQL 486
F+AN N + VWL + Y +VL A +N+R + C S+ LQL
Sbjct: 83 FRANRPNAEVVWLGLSNYQRVLGDEAIWENMRTTAHFLCWSIALQL 128
>UniRef50_Q6C8L5 Cluster: Yarrowia lipolytica chromosome D of strain
CLIB122 of Yarrowia lipolytica; n=1; Yarrowia
lipolytica|Rep: Yarrowia lipolytica chromosome D of
strain CLIB122 of Yarrowia lipolytica - Yarrowia
lipolytica (Candida lipolytica)
Length = 1149
Score = 34.3 bits (75), Expect = 4.0
Identities = 17/48 (35%), Positives = 26/48 (54%)
Frame = +2
Query: 152 PLNDSVSATFDTSVMCAKTSVSTHPDFVEDQIWLNGKEESFSNPRLQN 295
P++D V F T + T + PD+ D++ L+ + SF NPRL N
Sbjct: 330 PIDDHVQVEFSTPQLAPATLAN--PDYCIDEVLLSQGQSSFVNPRLLN 375
>UniRef50_Q18706 Cluster: Putative uncharacterized protein C49C8.2;
n=2; Caenorhabditis|Rep: Putative uncharacterized
protein C49C8.2 - Caenorhabditis elegans
Length = 172
Score = 33.9 bits (74), Expect = 5.3
Identities = 22/83 (26%), Positives = 43/83 (51%), Gaps = 3/83 (3%)
Frame = +2
Query: 566 DGSDSIATQIADSNHWPEMRVLVLVVGNTQKKVS--STVGMKIS-SETSELLKHRIQHCV 736
+ + I T I ++ + R+ ++ T + V+ T+ ++S S EL+ +H +
Sbjct: 5 NAAKEIVTAIQKADAEMKTRIQKMMKHRTLEDVAVLQTMLERVSQSSNKELISDFNKHQI 64
Query: 737 PQRTERIIXAIKNKDFYKFAEIQ 805
PQR +++ +KN + FAEIQ
Sbjct: 65 PQRLQKVASLVKNSHGHYFAEIQ 87
>UniRef50_A7Q958 Cluster: Chromosome chr19 scaffold_66, whole genome
shotgun sequence; n=2; Vitis vinifera|Rep: Chromosome
chr19 scaffold_66, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 684
Score = 33.1 bits (72), Expect = 9.2
Identities = 15/53 (28%), Positives = 30/53 (56%)
Frame = +2
Query: 155 LNDSVSATFDTSVMCAKTSVSTHPDFVEDQIWLNGKEESFSNPRLQNCLREIK 313
++ S+ ++ D +V+C +ST + VED++ L S+ P +C+ E+K
Sbjct: 556 ISTSLISSKDAAVLCPIAPISTMQNVVEDKLDLAAPVSSYGFPEDMDCVNEMK 608
>UniRef50_A2FK64 Cluster: Clan SB, family S8, subtilisin-like serine
peptidase; n=1; Trichomonas vaginalis G3|Rep: Clan SB,
family S8, subtilisin-like serine peptidase -
Trichomonas vaginalis G3
Length = 805
Score = 33.1 bits (72), Expect = 9.2
Identities = 14/32 (43%), Positives = 22/32 (68%)
Frame = +2
Query: 68 MSNIVTVIAPVNIAVIKYWGKRDEKLILPLND 163
M++ +T++ P++I + YW EK ILPLND
Sbjct: 691 MNDCLTMLQPISI--LSYWDTEPEKWILPLND 720
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 775,143,992
Number of Sequences: 1657284
Number of extensions: 15058718
Number of successful extensions: 37371
Number of sequences better than 10.0: 54
Number of HSP's better than 10.0 without gapping: 35872
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 37282
length of database: 575,637,011
effective HSP length: 100
effective length of database: 409,908,611
effective search space used: 75833093035
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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