Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P15_F_E06
(625 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X05344-1|CAA28955.1| 412|Homo sapiens cathepsin D protein. 193 4e-49
M63138-1|AAA51922.1| 412|Homo sapiens cathepsin D protein. 193 4e-49
M11233-1|AAB59529.1| 412|Homo sapiens CTSD protein. 193 4e-49
CR456947-1|CAG33228.1| 412|Homo sapiens CTSD protein. 193 4e-49
BT020155-1|AAV38957.1| 412|Homo sapiens cathepsin D (lysosomal ... 193 4e-49
BT006910-1|AAP35556.1| 412|Homo sapiens cathepsin D (lysosomal ... 193 4e-49
BC016320-1|AAH16320.1| 412|Homo sapiens cathepsin D protein. 193 4e-49
BC017842-1|AAH17842.1| 420|Homo sapiens napsin A aspartic pepti... 174 2e-43
AF200345-1|AAF17081.1| 420|Homo sapiens aspartyl protease 4 pro... 173 3e-43
AF098484-1|AAD13215.1| 420|Homo sapiens napsin 1 precursor prot... 173 3e-43
AF090386-1|AAD04917.1| 420|Homo sapiens napsin A protein. 173 3e-43
BC111705-1|AAI11706.1| 464|Homo sapiens NAPSB protein protein. 157 3e-38
AF200344-1|AAF17080.1| 450|Homo sapiens aspartyl protease 3 pro... 157 3e-38
M26901-1|AAA60364.1| 403|Homo sapiens renin protein. 153 5e-37
M10152-1|AAD03461.1| 406|Homo sapiens renin protein. 153 5e-37
L00073-1|AAA60363.1| 406|Homo sapiens renin protein. 153 5e-37
CR536498-1|CAG38737.1| 406|Homo sapiens REN protein. 153 5e-37
BC047752-1|AAH47752.1| 406|Homo sapiens renin protein. 153 5e-37
BC033474-1|AAH33474.1| 406|Homo sapiens renin protein. 153 5e-37
AY436324-1|AAR03502.1| 403|Homo sapiens renin protein. 153 5e-37
AL592146-1|CAI16594.1| 406|Homo sapiens renin protein. 153 5e-37
AL592114-1|CAH71224.1| 406|Homo sapiens renin protein. 153 5e-37
M84424-1|AAA52300.1| 396|Homo sapiens cathepsin E protein. 152 8e-37
J05036-1|AAA52130.1| 396|Homo sapiens CTSE protein. 152 8e-37
BX571818-5|CAH73265.1| 363|Homo sapiens cathepsin E protein. 152 8e-37
BX571818-4|CAH73264.1| 396|Homo sapiens cathepsin E protein. 152 8e-37
BC042537-1|AAH42537.1| 396|Homo sapiens cathepsin E protein. 152 8e-37
AJ250717-1|CAB82850.1| 396|Homo sapiens procathepsin E protein. 152 8e-37
AJ250716-1|CAB82849.1| 363|Homo sapiens cathepsin E, alternativ... 152 8e-37
U75272-1|AAB18273.1| 388|Homo sapiens gastricsin protein. 147 3e-35
M23077-1|AAA60063.1| 388|Homo sapiens pepsinogen C protein. 147 3e-35
M18667-1|AAA60062.1| 385|Homo sapiens pepsinogen protein. 147 3e-35
J04443-1|AAA60074.1| 388|Homo sapiens pepsinogen protein. 147 3e-35
BC073740-1|AAH73740.1| 388|Homo sapiens progastricsin (pepsinog... 147 3e-35
AL365205-1|CAI13181.1| 388|Homo sapiens progastricsin (pepsinog... 147 3e-35
J00287-1|AAA98529.1| 388|Homo sapiens PEP protein. 137 3e-32
BC029055-1|AAH29055.1| 388|Homo sapiens pepsinogen 5, group I (... 137 3e-32
M26032-1|AAA60061.1| 388|Homo sapiens pepsinogen A protein. 135 1e-31
X00063-1|CAA24937.1| 300|Homo sapiens protein ( Human kidney mR... 100 8e-21
BC014453-1|AAH14453.1| 518|Homo sapiens beta-site APP-cleaving ... 62 2e-09
AY358927-1|AAQ89286.1| 518|Homo sapiens BACE2 protein. 62 2e-09
AF212252-1|AAG41783.1| 439|Homo sapiens CDA13 protein. 62 2e-09
AF204944-1|AAF26368.1| 518|Homo sapiens transmembrane aspartic ... 62 2e-09
AF200342-1|AAF17078.1| 518|Homo sapiens aspartyl protease 1 pro... 62 2e-09
AF200192-1|AAF13714.1| 518|Homo sapiens memapsin 1 protein. 62 2e-09
AF188277-1|AAF35836.1| 396|Homo sapiens aspartyl protease protein. 62 2e-09
AF188276-1|AAF35835.1| 468|Homo sapiens aspartyl protease protein. 62 2e-09
AF178532-1|AAF29494.1| 518|Homo sapiens aspartyl protease protein. 62 2e-09
AF117892-1|AAD45240.1| 518|Homo sapiens aspartic-like protease ... 62 2e-09
AF050171-1|AAD45963.1| 518|Homo sapiens aspartyl protease protein. 62 2e-09
AK075539-1|BAC11682.1| 423|Homo sapiens protein ( Homo sapiens ... 60 5e-09
BC042578-1|AAH42578.1| 104|Homo sapiens PGC protein protein. 60 6e-09
DQ007053-1|AAY16982.1| 501|Homo sapiens beta-site APP-cleaving ... 53 7e-07
BC065492-1|AAH65492.1| 501|Homo sapiens beta-site APP-cleaving ... 53 7e-07
AF338816-1|AAK38374.1| 476|Homo sapiens beta-site APP cleaving ... 53 7e-07
AF204943-1|AAF26367.1| 501|Homo sapiens transmembrane aspartic ... 53 7e-07
AF201468-1|AAF18982.1| 501|Homo sapiens APP beta-secretase prot... 53 7e-07
AF200343-1|AAF17079.1| 501|Homo sapiens aspartyl protease 2 pro... 53 7e-07
AF200193-1|AAF13715.1| 488|Homo sapiens memapsin 2 protein. 53 7e-07
AF190725-1|AAF04142.1| 501|Homo sapiens beta-site APP cleaving ... 53 7e-07
AB050436-1|BAB40931.1| 476|Homo sapiens beta-site APP cleaving ... 53 7e-07
AB032975-1|BAA86463.2| 532|Homo sapiens KIAA1149 protein protein. 53 7e-07
BC036084-1|AAH36084.1| 501|Homo sapiens beta-site APP-cleaving ... 51 4e-06
AL163285-1|CAB90554.1| 415|Homo sapiens beta-site APP-cleaving ... 45 2e-04
AB050438-1|BAB40933.1| 432|Homo sapiens beta-site APP cleaving ... 41 0.003
AF338817-1|AAK38375.1| 457|Homo sapiens beta-site APP cleaving ... 41 0.004
AB050437-1|BAB40932.1| 457|Homo sapiens beta-site APP cleaving ... 41 0.004
AL365205-3|CAM16152.1| 86|Homo sapiens progastricsin (pepsinog... 38 0.022
AL365205-2|CAI95135.1| 140|Homo sapiens progastricsin (pepsinog... 37 0.067
AB089958-1|BAC81826.1| 127|Homo sapiens beta-site APP cleaving ... 36 0.15
BC030606-1|AAH30606.2| 514|Homo sapiens coiled-coil domain cont... 33 1.1
BC104851-1|AAI04852.1| 147|Homo sapiens LOC283174 protein protein. 31 3.3
BC101691-1|AAI01692.1| 147|Homo sapiens LOC283174 protein protein. 31 3.3
X85133-1|CAA59445.1| 948|Homo sapiens RB protein binding protei... 30 7.6
BC041063-1|AAH41063.1| 616|Homo sapiens eyes absent homolog 4 (... 30 7.6
AY072922-1|AAL68925.1| 1625|Homo sapiens p53-associated cellular... 30 7.6
AL450270-3|CAI41273.1| 605|Homo sapiens eyes absent homolog 4 (... 30 7.6
AL450270-2|CAI41272.1| 639|Homo sapiens eyes absent homolog 4 (... 30 7.6
AL121959-1|CAB92069.2| 639|Homo sapiens eyes absent homolog 4 (... 30 7.6
AL024497-3|CAI42525.1| 605|Homo sapiens eyes absent homolog 4 (... 30 7.6
AL024497-2|CAI42524.1| 639|Homo sapiens eyes absent homolog 4 (... 30 7.6
AF352051-1|AAL05625.1| 1616|Homo sapiens proliferation potential... 30 7.6
AB112075-1|BAC77637.1| 1758|Homo sapiens retinoblastoma binding ... 30 7.6
AB112074-1|BAC77636.1| 1792|Homo sapiens retinoblastoma binding ... 30 7.6
>X05344-1|CAA28955.1| 412|Homo sapiens cathepsin D protein.
Length = 412
Score = 193 bits (471), Expect = 4e-49
Identities = 103/187 (55%), Positives = 122/187 (65%), Gaps = 22/187 (11%)
Frame = +1
Query: 130 ALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEPLSNYLDAQY 276
AL R+PLH+ + R EVG +E L K V+ GP PE L NY+DAQY
Sbjct: 20 ALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEVLKNYMDAQY 79
Query: 277 YGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQFA 456
YG I IGTPPQ F VVFDTGSSNLWVPS C +IAC +H+KY+S KS++YV NGT F
Sbjct: 80 YGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSDKSSTYVKNGTSFD 139
Query: 457 IQYGSGSLSGFLSTDDVTV-----------GGLKVRRQTFAEAVSEPGLAFVAAKFDGIL 603
I YGSGSLSG+LS D V+V GG+KV RQ F EA +PG+ F+AAKFDGIL
Sbjct: 140 IHYGSGSLSGYLSQDTVSVPCQSASSASALGGVKVERQVFGEATKQPGITFIAAKFDGIL 199
Query: 604 GMAFXTI 624
GMA+ I
Sbjct: 200 GMAYPRI 206
>M63138-1|AAA51922.1| 412|Homo sapiens cathepsin D protein.
Length = 412
Score = 193 bits (471), Expect = 4e-49
Identities = 103/187 (55%), Positives = 122/187 (65%), Gaps = 22/187 (11%)
Frame = +1
Query: 130 ALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEPLSNYLDAQY 276
AL R+PLH+ + R EVG +E L K V+ GP PE L NY+DAQY
Sbjct: 20 ALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEVLKNYMDAQY 79
Query: 277 YGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQFA 456
YG I IGTPPQ F VVFDTGSSNLWVPS C +IAC +H+KY+S KS++YV NGT F
Sbjct: 80 YGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSDKSSTYVKNGTSFD 139
Query: 457 IQYGSGSLSGFLSTDDVTV-----------GGLKVRRQTFAEAVSEPGLAFVAAKFDGIL 603
I YGSGSLSG+LS D V+V GG+KV RQ F EA +PG+ F+AAKFDGIL
Sbjct: 140 IHYGSGSLSGYLSQDTVSVPCQSASSASALGGVKVERQVFGEATKQPGITFIAAKFDGIL 199
Query: 604 GMAFXTI 624
GMA+ I
Sbjct: 200 GMAYPRI 206
>M11233-1|AAB59529.1| 412|Homo sapiens CTSD protein.
Length = 412
Score = 193 bits (471), Expect = 4e-49
Identities = 103/187 (55%), Positives = 122/187 (65%), Gaps = 22/187 (11%)
Frame = +1
Query: 130 ALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEPLSNYLDAQY 276
AL R+PLH+ + R EVG +E L K V+ GP PE L NY+DAQY
Sbjct: 20 ALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEVLKNYMDAQY 79
Query: 277 YGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQFA 456
YG I IGTPPQ F VVFDTGSSNLWVPS C +IAC +H+KY+S KS++YV NGT F
Sbjct: 80 YGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSDKSSTYVKNGTSFD 139
Query: 457 IQYGSGSLSGFLSTDDVTV-----------GGLKVRRQTFAEAVSEPGLAFVAAKFDGIL 603
I YGSGSLSG+LS D V+V GG+KV RQ F EA +PG+ F+AAKFDGIL
Sbjct: 140 IHYGSGSLSGYLSQDTVSVPCQSASSASALGGVKVERQVFGEATKQPGITFIAAKFDGIL 199
Query: 604 GMAFXTI 624
GMA+ I
Sbjct: 200 GMAYPRI 206
>CR456947-1|CAG33228.1| 412|Homo sapiens CTSD protein.
Length = 412
Score = 193 bits (471), Expect = 4e-49
Identities = 103/187 (55%), Positives = 122/187 (65%), Gaps = 22/187 (11%)
Frame = +1
Query: 130 ALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEPLSNYLDAQY 276
AL R+PLH+ + R EVG +E L K V+ GP PE L NY+DAQY
Sbjct: 20 ALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEVLKNYMDAQY 79
Query: 277 YGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQFA 456
YG I IGTPPQ F VVFDTGSSNLWVPS C +IAC +H+KY+S KS++YV NGT F
Sbjct: 80 YGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSDKSSTYVKNGTSFD 139
Query: 457 IQYGSGSLSGFLSTDDVTV-----------GGLKVRRQTFAEAVSEPGLAFVAAKFDGIL 603
I YGSGSLSG+LS D V+V GG+KV RQ F EA +PG+ F+AAKFDGIL
Sbjct: 140 IHYGSGSLSGYLSQDTVSVPCQSASSASALGGVKVERQVFGEATKQPGITFIAAKFDGIL 199
Query: 604 GMAFXTI 624
GMA+ I
Sbjct: 200 GMAYPRI 206
>BT020155-1|AAV38957.1| 412|Homo sapiens cathepsin D (lysosomal
aspartyl protease) protein.
Length = 412
Score = 193 bits (471), Expect = 4e-49
Identities = 103/187 (55%), Positives = 122/187 (65%), Gaps = 22/187 (11%)
Frame = +1
Query: 130 ALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEPLSNYLDAQY 276
AL R+PLH+ + R EVG +E L K V+ GP PE L NY+DAQY
Sbjct: 20 ALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEVLKNYMDAQY 79
Query: 277 YGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQFA 456
YG I IGTPPQ F VVFDTGSSNLWVPS C +IAC +H+KY+S KS++YV NGT F
Sbjct: 80 YGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSDKSSTYVKNGTSFD 139
Query: 457 IQYGSGSLSGFLSTDDVTV-----------GGLKVRRQTFAEAVSEPGLAFVAAKFDGIL 603
I YGSGSLSG+LS D V+V GG+KV RQ F EA +PG+ F+AAKFDGIL
Sbjct: 140 IHYGSGSLSGYLSQDTVSVPCQSASSASALGGVKVERQVFGEATKQPGITFIAAKFDGIL 199
Query: 604 GMAFXTI 624
GMA+ I
Sbjct: 200 GMAYPRI 206
>BT006910-1|AAP35556.1| 412|Homo sapiens cathepsin D (lysosomal
aspartyl protease) protein.
Length = 412
Score = 193 bits (471), Expect = 4e-49
Identities = 103/187 (55%), Positives = 122/187 (65%), Gaps = 22/187 (11%)
Frame = +1
Query: 130 ALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEPLSNYLDAQY 276
AL R+PLH+ + R EVG +E L K V+ GP PE L NY+DAQY
Sbjct: 20 ALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEVLKNYMDAQY 79
Query: 277 YGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQFA 456
YG I IGTPPQ F VVFDTGSSNLWVPS C +IAC +H+KY+S KS++YV NGT F
Sbjct: 80 YGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSDKSSTYVKNGTSFD 139
Query: 457 IQYGSGSLSGFLSTDDVTV-----------GGLKVRRQTFAEAVSEPGLAFVAAKFDGIL 603
I YGSGSLSG+LS D V+V GG+KV RQ F EA +PG+ F+AAKFDGIL
Sbjct: 140 IHYGSGSLSGYLSQDTVSVPCQSASSASALGGVKVERQVFGEATKQPGITFIAAKFDGIL 199
Query: 604 GMAFXTI 624
GMA+ I
Sbjct: 200 GMAYPRI 206
>BC016320-1|AAH16320.1| 412|Homo sapiens cathepsin D protein.
Length = 412
Score = 193 bits (471), Expect = 4e-49
Identities = 103/187 (55%), Positives = 122/187 (65%), Gaps = 22/187 (11%)
Frame = +1
Query: 130 ALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEPLSNYLDAQY 276
AL R+PLH+ + R EVG +E L K V+ GP PE L NY+DAQY
Sbjct: 20 ALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEVLKNYMDAQY 79
Query: 277 YGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQFA 456
YG I IGTPPQ F VVFDTGSSNLWVPS C +IAC +H+KY+S KS++YV NGT F
Sbjct: 80 YGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSDKSSTYVKNGTSFD 139
Query: 457 IQYGSGSLSGFLSTDDVTV-----------GGLKVRRQTFAEAVSEPGLAFVAAKFDGIL 603
I YGSGSLSG+LS D V+V GG+KV RQ F EA +PG+ F+AAKFDGIL
Sbjct: 140 IHYGSGSLSGYLSQDTVSVPCQSASSASALGGVKVERQVFGEATKQPGITFIAAKFDGIL 199
Query: 604 GMAFXTI 624
GMA+ I
Sbjct: 200 GMAYPRI 206
>BC017842-1|AAH17842.1| 420|Homo sapiens napsin A aspartic
peptidase protein.
Length = 420
Score = 174 bits (423), Expect = 2e-43
Identities = 83/166 (50%), Positives = 111/166 (66%), Gaps = 5/166 (3%)
Frame = +1
Query: 133 LYRVPLHRMKTARTHFHEVG---TELELLRLKYDVTGPSP--EPLSNYLDAQYYGVISIG 297
L R+PLHR++ R + + EL +L G P PLSNY D QY+G I +G
Sbjct: 26 LIRIPLHRVQPGRRTLNLLRGWREPAELPKLGAPSPGDKPIFVPLSNYRDVQYFGEIGLG 85
Query: 298 TPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQFAIQYGSGS 477
TPPQ+F V FDTGSSNLWVPS++CH+ ++ C LH+++D + S+S+ ANGT+FAIQYG+G
Sbjct: 86 TPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWLHHRFDPKASSSFQANGTKFAIQYGTGR 145
Query: 478 LSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDGILGMAF 615
+ G LS D +T+GG+K F EA+ EP L F A FDGILG+ F
Sbjct: 146 VDGILSEDKLTIGGIKGASVIFGEALWEPSLVFAFAHFDGILGLGF 191
>AF200345-1|AAF17081.1| 420|Homo sapiens aspartyl protease 4
protein.
Length = 420
Score = 173 bits (422), Expect = 3e-43
Identities = 83/166 (50%), Positives = 111/166 (66%), Gaps = 5/166 (3%)
Frame = +1
Query: 133 LYRVPLHRMKTARTHFHEVG---TELELLRLKYDVTGPSP--EPLSNYLDAQYYGVISIG 297
L R+PLHR++ R + + EL +L G P PLSNY D QY+G I +G
Sbjct: 26 LIRIPLHRVQPGRRILNLLRGWREPAELPKLGAPSPGDKPIFVPLSNYRDVQYFGEIGLG 85
Query: 298 TPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQFAIQYGSGS 477
TPPQ+F V FDTGSSNLWVPS++CH+ ++ C LH+++D + S+S+ ANGT+FAIQYG+G
Sbjct: 86 TPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWLHHRFDPKASSSFQANGTKFAIQYGTGR 145
Query: 478 LSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDGILGMAF 615
+ G LS D +T+GG+K F EA+ EP L F A FDGILG+ F
Sbjct: 146 VDGILSEDKLTIGGIKGASVIFGEALWEPSLVFAFAHFDGILGLGF 191
>AF098484-1|AAD13215.1| 420|Homo sapiens napsin 1 precursor
protein.
Length = 420
Score = 173 bits (422), Expect = 3e-43
Identities = 83/166 (50%), Positives = 111/166 (66%), Gaps = 5/166 (3%)
Frame = +1
Query: 133 LYRVPLHRMKTARTHFHEVG---TELELLRLKYDVTGPSP--EPLSNYLDAQYYGVISIG 297
L R+PLHR++ R + + EL +L G P PLSNY D QY+G I +G
Sbjct: 26 LIRIPLHRVQPGRRILNLLRGWREPAELPKLGAPSPGDKPIFVPLSNYRDVQYFGEIGLG 85
Query: 298 TPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQFAIQYGSGS 477
TPPQ+F V FDTGSSNLWVPS++CH+ ++ C LH+++D + S+S+ ANGT+FAIQYG+G
Sbjct: 86 TPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWLHHRFDPKASSSFQANGTKFAIQYGTGR 145
Query: 478 LSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDGILGMAF 615
+ G LS D +T+GG+K F EA+ EP L F A FDGILG+ F
Sbjct: 146 VDGILSEDKLTIGGIKGASVIFGEALWEPSLVFAFAHFDGILGLGF 191
>AF090386-1|AAD04917.1| 420|Homo sapiens napsin A protein.
Length = 420
Score = 173 bits (422), Expect = 3e-43
Identities = 83/166 (50%), Positives = 111/166 (66%), Gaps = 5/166 (3%)
Frame = +1
Query: 133 LYRVPLHRMKTARTHFHEVG---TELELLRLKYDVTGPSP--EPLSNYLDAQYYGVISIG 297
L R+PLHR++ R + + EL +L G P PLSNY D QY+G I +G
Sbjct: 26 LIRIPLHRVQPGRRILNLLRGWREPAELPKLGAPSPGDKPIFVPLSNYRDVQYFGEIGLG 85
Query: 298 TPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQFAIQYGSGS 477
TPPQ+F V FDTGSSNLWVPS++CH+ ++ C LH+++D + S+S+ ANGT+FAIQYG+G
Sbjct: 86 TPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWLHHRFDPKASSSFQANGTKFAIQYGTGR 145
Query: 478 LSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDGILGMAF 615
+ G LS D +T+GG+K F EA+ EP L F A FDGILG+ F
Sbjct: 146 VDGILSEDKLTIGGIKGASVIFGEALWEPSLVFAFAHFDGILGLGF 191
>BC111705-1|AAI11706.1| 464|Homo sapiens NAPSB protein protein.
Length = 464
Score = 157 bits (381), Expect = 3e-38
Identities = 75/166 (45%), Positives = 107/166 (64%), Gaps = 5/166 (3%)
Frame = +1
Query: 133 LYRVPLHRMKTARTHFHEV---GTELELLRLKYDVTGPSPE--PLSNYLDAQYYGVISIG 297
L R+PL ++ R + + G EL +L G P PLS +LDAQY+G I +G
Sbjct: 22 LIRIPLRQVHPGRRTLNLLRGWGKPAELPKLGAPSPGDKPASVPLSKFLDAQYFGEIGLG 81
Query: 298 TPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQFAIQYGSGS 477
TPPQ+F V FDTGSSNLWVPS++CH+ ++ C H++++ S+S+ +GT+FAIQYG+G
Sbjct: 82 TPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWFHHRFNPNASSSFKPSGTKFAIQYGTGR 141
Query: 478 LSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDGILGMAF 615
+ G LS D +T+GG+K F EA+ E L F ++ DGILG+ F
Sbjct: 142 VDGILSEDKLTIGGIKGASVIFGEALWESSLVFTVSRPDGILGLGF 187
>AF200344-1|AAF17080.1| 450|Homo sapiens aspartyl protease 3
protein.
Length = 450
Score = 157 bits (381), Expect = 3e-38
Identities = 75/166 (45%), Positives = 107/166 (64%), Gaps = 5/166 (3%)
Frame = +1
Query: 133 LYRVPLHRMKTARTHFHEV---GTELELLRLKYDVTGPSPE--PLSNYLDAQYYGVISIG 297
L R+PL ++ R + + G EL +L G P PLS +LDAQY+G I +G
Sbjct: 26 LIRIPLRQVHPGRRTLNLLRGWGKPAELPKLGAPSPGDKPASVPLSKFLDAQYFGEIGLG 85
Query: 298 TPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQFAIQYGSGS 477
TPPQ+F V FDTGSSNLWVPS++CH+ ++ C H++++ S+S+ +GT+FAIQYG+G
Sbjct: 86 TPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWFHHRFNPNASSSFKPSGTKFAIQYGTGR 145
Query: 478 LSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDGILGMAF 615
+ G LS D +T+GG+K F EA+ E L F ++ DGILG+ F
Sbjct: 146 VDGILSEDKLTIGGIKGASVIFGEALWESSLVFTVSRPDGILGLGF 191
>M26901-1|AAA60364.1| 403|Homo sapiens renin protein.
Length = 403
Score = 153 bits (371), Expect = 5e-37
Identities = 68/122 (55%), Positives = 88/122 (72%)
Frame = +1
Query: 250 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTS 429
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC+ H +D+ S+S
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137
Query: 430 YVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDGILGM 609
Y NGT+ ++Y +G++SGFLS D +TVGG+ V Q F E P L F+ A+FDG++GM
Sbjct: 138 YKHNGTELTLRYSTGTVSGFLSQDIITVGGITV-TQMFGEVTEMPALPFMLAQFDGVVGM 196
Query: 610 AF 615
F
Sbjct: 197 GF 198
>M10152-1|AAD03461.1| 406|Homo sapiens renin protein.
Length = 406
Score = 153 bits (371), Expect = 5e-37
Identities = 68/122 (55%), Positives = 88/122 (72%)
Frame = +1
Query: 250 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTS 429
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC+ H +D+ S+S
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137
Query: 430 YVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDGILGM 609
Y NGT+ ++Y +G++SGFLS D +TVGG+ V Q F E P L F+ A+FDG++GM
Sbjct: 138 YKHNGTELTLRYSTGTVSGFLSQDIITVGGITV-TQMFGEVTEMPALPFMLAEFDGVVGM 196
Query: 610 AF 615
F
Sbjct: 197 GF 198
>L00073-1|AAA60363.1| 406|Homo sapiens renin protein.
Length = 406
Score = 153 bits (371), Expect = 5e-37
Identities = 68/122 (55%), Positives = 88/122 (72%)
Frame = +1
Query: 250 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTS 429
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC+ H +D+ S+S
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137
Query: 430 YVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDGILGM 609
Y NGT+ ++Y +G++SGFLS D +TVGG+ V Q F E P L F+ A+FDG++GM
Sbjct: 138 YKHNGTELTLRYSTGTVSGFLSQDIITVGGITV-TQMFGEVTEMPALPFMLAEFDGVVGM 196
Query: 610 AF 615
F
Sbjct: 197 GF 198
>CR536498-1|CAG38737.1| 406|Homo sapiens REN protein.
Length = 406
Score = 153 bits (371), Expect = 5e-37
Identities = 68/122 (55%), Positives = 88/122 (72%)
Frame = +1
Query: 250 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTS 429
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC+ H +D+ S+S
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137
Query: 430 YVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDGILGM 609
Y NGT+ ++Y +G++SGFLS D +TVGG+ V Q F E P L F+ A+FDG++GM
Sbjct: 138 YKHNGTELTLRYSTGTVSGFLSQDIITVGGITV-TQMFGEVTEMPALPFMLAEFDGVVGM 196
Query: 610 AF 615
F
Sbjct: 197 GF 198
>BC047752-1|AAH47752.1| 406|Homo sapiens renin protein.
Length = 406
Score = 153 bits (371), Expect = 5e-37
Identities = 68/122 (55%), Positives = 88/122 (72%)
Frame = +1
Query: 250 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTS 429
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC+ H +D+ S+S
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137
Query: 430 YVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDGILGM 609
Y NGT+ ++Y +G++SGFLS D +TVGG+ V Q F E P L F+ A+FDG++GM
Sbjct: 138 YKHNGTELTLRYSTGTVSGFLSQDIITVGGITV-TQMFGEVTEMPALPFMLAEFDGVVGM 196
Query: 610 AF 615
F
Sbjct: 197 GF 198
>BC033474-1|AAH33474.1| 406|Homo sapiens renin protein.
Length = 406
Score = 153 bits (371), Expect = 5e-37
Identities = 68/122 (55%), Positives = 88/122 (72%)
Frame = +1
Query: 250 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTS 429
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC+ H +D+ S+S
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137
Query: 430 YVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDGILGM 609
Y NGT+ ++Y +G++SGFLS D +TVGG+ V Q F E P L F+ A+FDG++GM
Sbjct: 138 YKHNGTELTLRYSTGTVSGFLSQDIITVGGITV-TQMFGEVTEMPALPFMLAEFDGVVGM 196
Query: 610 AF 615
F
Sbjct: 197 GF 198
>AY436324-1|AAR03502.1| 403|Homo sapiens renin protein.
Length = 403
Score = 153 bits (371), Expect = 5e-37
Identities = 68/122 (55%), Positives = 88/122 (72%)
Frame = +1
Query: 250 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTS 429
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC+ H +D+ S+S
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137
Query: 430 YVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDGILGM 609
Y NGT+ ++Y +G++SGFLS D +TVGG+ V Q F E P L F+ A+FDG++GM
Sbjct: 138 YKHNGTELTLRYSTGTVSGFLSQDIITVGGITV-TQMFGEVTEMPALPFMLAEFDGVVGM 196
Query: 610 AF 615
F
Sbjct: 197 GF 198
>AL592146-1|CAI16594.1| 406|Homo sapiens renin protein.
Length = 406
Score = 153 bits (371), Expect = 5e-37
Identities = 68/122 (55%), Positives = 88/122 (72%)
Frame = +1
Query: 250 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTS 429
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC+ H +D+ S+S
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137
Query: 430 YVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDGILGM 609
Y NGT+ ++Y +G++SGFLS D +TVGG+ V Q F E P L F+ A+FDG++GM
Sbjct: 138 YKHNGTELTLRYSTGTVSGFLSQDIITVGGITV-TQMFGEVTEMPALPFMLAEFDGVVGM 196
Query: 610 AF 615
F
Sbjct: 197 GF 198
>AL592114-1|CAH71224.1| 406|Homo sapiens renin protein.
Length = 406
Score = 153 bits (371), Expect = 5e-37
Identities = 68/122 (55%), Positives = 88/122 (72%)
Frame = +1
Query: 250 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTS 429
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC+ H +D+ S+S
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137
Query: 430 YVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDGILGM 609
Y NGT+ ++Y +G++SGFLS D +TVGG+ V Q F E P L F+ A+FDG++GM
Sbjct: 138 YKHNGTELTLRYSTGTVSGFLSQDIITVGGITV-TQMFGEVTEMPALPFMLAEFDGVVGM 196
Query: 610 AF 615
F
Sbjct: 197 GF 198
>M84424-1|AAA52300.1| 396|Homo sapiens cathepsin E protein.
Length = 396
Score = 152 bits (369), Expect = 8e-37
Identities = 80/175 (45%), Positives = 112/175 (64%), Gaps = 10/175 (5%)
Frame = +1
Query: 130 ALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSPEPLSNYLDAQYY 279
+L+RVPL R + AR+ E L +++ + + EPL NYLD +Y+
Sbjct: 20 SLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAKEPLINYLDMEYF 79
Query: 280 GVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQFAI 459
G ISIG+PPQ+F V+FDTGSSNLWVPS C T+ AC H+++ +S++Y G F+I
Sbjct: 80 GTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPACKTHSRFQPSQSSTYSQPGQSFSI 137
Query: 460 QYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFXTI 624
QYG+GSLSG + D V+V GL V Q F E+V+EPG FV A+FDGILG+ + ++
Sbjct: 138 QYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGILGLGYPSL 192
>J05036-1|AAA52130.1| 396|Homo sapiens CTSE protein.
Length = 396
Score = 152 bits (369), Expect = 8e-37
Identities = 80/175 (45%), Positives = 112/175 (64%), Gaps = 10/175 (5%)
Frame = +1
Query: 130 ALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSPEPLSNYLDAQYY 279
+L+RVPL R + AR+ E L +++ + + EPL NYLD +Y+
Sbjct: 20 SLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAKEPLINYLDMEYF 79
Query: 280 GVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQFAI 459
G ISIG+PPQ+F V+FDTGSSNLWVPS C T+ AC H+++ +S++Y G F+I
Sbjct: 80 GTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPACKTHSRFQPSQSSTYSQPGQSFSI 137
Query: 460 QYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFXTI 624
QYG+GSLSG + D V+V GL V Q F E+V+EPG FV A+FDGILG+ + ++
Sbjct: 138 QYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGILGLGYPSL 192
>BX571818-5|CAH73265.1| 363|Homo sapiens cathepsin E protein.
Length = 363
Score = 152 bits (369), Expect = 8e-37
Identities = 80/175 (45%), Positives = 112/175 (64%), Gaps = 10/175 (5%)
Frame = +1
Query: 130 ALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSPEPLSNYLDAQYY 279
+L+RVPL R + AR+ E L +++ + + EPL NYLD +Y+
Sbjct: 20 SLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAKEPLINYLDMEYF 79
Query: 280 GVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQFAI 459
G ISIG+PPQ+F V+FDTGSSNLWVPS C T+ AC H+++ +S++Y G F+I
Sbjct: 80 GTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPACKTHSRFQPSQSSTYSQPGQSFSI 137
Query: 460 QYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFXTI 624
QYG+GSLSG + D V+V GL V Q F E+V+EPG FV A+FDGILG+ + ++
Sbjct: 138 QYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGILGLGYPSL 192
>BX571818-4|CAH73264.1| 396|Homo sapiens cathepsin E protein.
Length = 396
Score = 152 bits (369), Expect = 8e-37
Identities = 80/175 (45%), Positives = 112/175 (64%), Gaps = 10/175 (5%)
Frame = +1
Query: 130 ALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSPEPLSNYLDAQYY 279
+L+RVPL R + AR+ E L +++ + + EPL NYLD +Y+
Sbjct: 20 SLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAKEPLINYLDMEYF 79
Query: 280 GVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQFAI 459
G ISIG+PPQ+F V+FDTGSSNLWVPS C T+ AC H+++ +S++Y G F+I
Sbjct: 80 GTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPACKTHSRFQPSQSSTYSQPGQSFSI 137
Query: 460 QYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFXTI 624
QYG+GSLSG + D V+V GL V Q F E+V+EPG FV A+FDGILG+ + ++
Sbjct: 138 QYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGILGLGYPSL 192
>BC042537-1|AAH42537.1| 396|Homo sapiens cathepsin E protein.
Length = 396
Score = 152 bits (369), Expect = 8e-37
Identities = 80/175 (45%), Positives = 112/175 (64%), Gaps = 10/175 (5%)
Frame = +1
Query: 130 ALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSPEPLSNYLDAQYY 279
+L+RVPL R + AR+ E L +++ + + EPL NYLD +Y+
Sbjct: 20 SLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAKEPLINYLDMEYF 79
Query: 280 GVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQFAI 459
G ISIG+PPQ+F V+FDTGSSNLWVPS C T+ AC H+++ +S++Y G F+I
Sbjct: 80 GTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPACKTHSRFQPSQSSTYSQPGQSFSI 137
Query: 460 QYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFXTI 624
QYG+GSLSG + D V+V GL V Q F E+V+EPG FV A+FDGILG+ + ++
Sbjct: 138 QYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGILGLGYPSL 192
>AJ250717-1|CAB82850.1| 396|Homo sapiens procathepsin E protein.
Length = 396
Score = 152 bits (369), Expect = 8e-37
Identities = 80/175 (45%), Positives = 112/175 (64%), Gaps = 10/175 (5%)
Frame = +1
Query: 130 ALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSPEPLSNYLDAQYY 279
+L+RVPL R + AR+ E L +++ + + EPL NYLD +Y+
Sbjct: 20 SLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAKEPLINYLDMEYF 79
Query: 280 GVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQFAI 459
G ISIG+PPQ+F V+FDTGSSNLWVPS C T+ AC H+++ +S++Y G F+I
Sbjct: 80 GTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPACKTHSRFQPSQSSTYSQPGQSFSI 137
Query: 460 QYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFXTI 624
QYG+GSLSG + D V+V GL V Q F E+V+EPG FV A+FDGILG+ + ++
Sbjct: 138 QYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGILGLGYPSL 192
>AJ250716-1|CAB82849.1| 363|Homo sapiens cathepsin E, alternative
protein.
Length = 363
Score = 152 bits (369), Expect = 8e-37
Identities = 80/175 (45%), Positives = 112/175 (64%), Gaps = 10/175 (5%)
Frame = +1
Query: 130 ALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSPEPLSNYLDAQYY 279
+L+RVPL R + AR+ E L +++ + + EPL NYLD +Y+
Sbjct: 20 SLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAKEPLINYLDMEYF 79
Query: 280 GVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQFAI 459
G ISIG+PPQ+F V+FDTGSSNLWVPS C T+ AC H+++ +S++Y G F+I
Sbjct: 80 GTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPACKTHSRFQPSQSSTYSQPGQSFSI 137
Query: 460 QYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFXTI 624
QYG+GSLSG + D V+V GL V Q F E+V+EPG FV A+FDGILG+ + ++
Sbjct: 138 QYGTGSLSGIIGADQVSVEGLTVVGQQFGESVTEPGQTFVDAEFDGILGLGYPSL 192
>U75272-1|AAB18273.1| 388|Homo sapiens gastricsin protein.
Length = 388
Score = 147 bits (356), Expect = 3e-35
Identities = 79/171 (46%), Positives = 110/171 (64%), Gaps = 9/171 (5%)
Frame = +1
Query: 130 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 282
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 17 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 75
Query: 283 VISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQFAIQ 462
ISIGTPPQ+F V+FDTGSSNLWVPS C + AC H++++ +S++Y NG F++Q
Sbjct: 76 EISIGTPPQNFLVLFDTGSSNLWVPSVYCQ--SQACTSHSRFNPSESSTYSTNGQTFSLQ 133
Query: 463 YGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDGILGMAF 615
YGSGSL+GF D +TV ++V Q F + +EPG FV A+FDGI+G+A+
Sbjct: 134 YGSGSLTGFFGYDTLTVQSIQVPNQEFGLSENEPGTNFVYAQFDGIMGLAY 184
>M23077-1|AAA60063.1| 388|Homo sapiens pepsinogen C protein.
Length = 388
Score = 147 bits (356), Expect = 3e-35
Identities = 79/171 (46%), Positives = 110/171 (64%), Gaps = 9/171 (5%)
Frame = +1
Query: 130 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 282
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 17 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 75
Query: 283 VISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQFAIQ 462
ISIGTPPQ+F V+FDTGSSNLWVPS C + AC H++++ +S++Y NG F++Q
Sbjct: 76 EISIGTPPQNFLVLFDTGSSNLWVPSVYCQ--SQACTSHSRFNPSESSTYSTNGQTFSLQ 133
Query: 463 YGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDGILGMAF 615
YGSGSL+GF D +TV ++V Q F + +EPG FV A+FDGI+G+A+
Sbjct: 134 YGSGSLTGFFGYDTLTVQSIQVPNQEFGLSENEPGTNFVYAQFDGIMGLAY 184
>M18667-1|AAA60062.1| 385|Homo sapiens pepsinogen protein.
Length = 385
Score = 147 bits (356), Expect = 3e-35
Identities = 79/171 (46%), Positives = 110/171 (64%), Gaps = 9/171 (5%)
Frame = +1
Query: 130 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 282
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 14 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 72
Query: 283 VISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQFAIQ 462
ISIGTPPQ+F V+FDTGSSNLWVPS C + AC H++++ +S++Y NG F++Q
Sbjct: 73 EISIGTPPQNFLVLFDTGSSNLWVPSVYCQ--SQACTSHSRFNPSESSTYSTNGQTFSLQ 130
Query: 463 YGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDGILGMAF 615
YGSGSL+GF D +TV ++V Q F + +EPG FV A+FDGI+G+A+
Sbjct: 131 YGSGSLTGFFGYDTLTVQSIQVPNQEFGLSENEPGTNFVYAQFDGIMGLAY 181
>J04443-1|AAA60074.1| 388|Homo sapiens pepsinogen protein.
Length = 388
Score = 147 bits (356), Expect = 3e-35
Identities = 79/171 (46%), Positives = 110/171 (64%), Gaps = 9/171 (5%)
Frame = +1
Query: 130 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 282
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 17 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 75
Query: 283 VISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQFAIQ 462
ISIGTPPQ+F V+FDTGSSNLWVPS C + AC H++++ +S++Y NG F++Q
Sbjct: 76 EISIGTPPQNFLVLFDTGSSNLWVPSVYCQ--SQACTSHSRFNPSESSTYSTNGQTFSLQ 133
Query: 463 YGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDGILGMAF 615
YGSGSL+GF D +TV ++V Q F + +EPG FV A+FDGI+G+A+
Sbjct: 134 YGSGSLTGFFGYDTLTVQSIQVPNQEFGLSENEPGTNFVYAQFDGIMGLAY 184
>BC073740-1|AAH73740.1| 388|Homo sapiens progastricsin (pepsinogen
C) protein.
Length = 388
Score = 147 bits (356), Expect = 3e-35
Identities = 79/171 (46%), Positives = 110/171 (64%), Gaps = 9/171 (5%)
Frame = +1
Query: 130 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 282
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 17 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 75
Query: 283 VISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQFAIQ 462
ISIGTPPQ+F V+FDTGSSNLWVPS C + AC H++++ +S++Y NG F++Q
Sbjct: 76 EISIGTPPQNFLVLFDTGSSNLWVPSVYCQ--SQACTSHSRFNPSESSTYSTNGQTFSLQ 133
Query: 463 YGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDGILGMAF 615
YGSGSL+GF D +TV ++V Q F + +EPG FV A+FDGI+G+A+
Sbjct: 134 YGSGSLTGFFGYDTLTVQSIQVPNQEFGLSENEPGTNFVYAQFDGIMGLAY 184
>AL365205-1|CAI13181.1| 388|Homo sapiens progastricsin (pepsinogen
C) protein.
Length = 388
Score = 147 bits (356), Expect = 3e-35
Identities = 79/171 (46%), Positives = 110/171 (64%), Gaps = 9/171 (5%)
Frame = +1
Query: 130 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 282
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 17 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 75
Query: 283 VISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQFAIQ 462
ISIGTPPQ+F V+FDTGSSNLWVPS C + AC H++++ +S++Y NG F++Q
Sbjct: 76 EISIGTPPQNFLVLFDTGSSNLWVPSVYCQ--SQACTSHSRFNPSESSTYSTNGQTFSLQ 133
Query: 463 YGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDGILGMAF 615
YGSGSL+GF D +TV ++V Q F + +EPG FV A+FDGI+G+A+
Sbjct: 134 YGSGSLTGFFGYDTLTVQSIQVPNQEFGLSENEPGTNFVYAQFDGIMGLAY 184
>J00287-1|AAA98529.1| 388|Homo sapiens PEP protein.
Length = 388
Score = 137 bits (331), Expect = 3e-32
Identities = 75/176 (42%), Positives = 103/176 (58%), Gaps = 12/176 (6%)
Frame = +1
Query: 133 LYRVPLHRMKTARTHFHEVGTELELLRL-------KYDVTGPSP-----EPLSNYLDAQY 276
+Y+VPL R K+ R E G + L+ KY +P +PL NYLD +Y
Sbjct: 17 MYKVPLIRKKSLRRTLSERGLLKDFLKKHNLNPARKYFPQWEAPTLVDEQPLENYLDMEY 76
Query: 277 YGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQFA 456
+G I IGTP Q F VVFDTGSSNLWVPS C +++AC HN+++ S++Y + +
Sbjct: 77 FGTIGIGTPAQDFTVVFDTGSSNLWVPSVYC--SSLACTNHNRFNPEDSSTYQSTSETVS 134
Query: 457 IQYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFXTI 624
I YG+GS++G L D V VGG+ Q F + +EPG A FDGILG+A+ +I
Sbjct: 135 ITYGTGSMTGILGYDTVQVGGISDTNQIFGLSETEPGSFLYYAPFDGILGLAYPSI 190
>BC029055-1|AAH29055.1| 388|Homo sapiens pepsinogen 5, group I
(pepsinogen A) protein.
Length = 388
Score = 137 bits (331), Expect = 3e-32
Identities = 75/176 (42%), Positives = 103/176 (58%), Gaps = 12/176 (6%)
Frame = +1
Query: 133 LYRVPLHRMKTARTHFHEVGTELELLRL-------KYDVTGPSP-----EPLSNYLDAQY 276
+Y+VPL R K+ R E G + L+ KY +P +PL NYLD +Y
Sbjct: 17 MYKVPLIRKKSLRRTLSERGLLKDFLKKHNLNPARKYFPQWEAPTLVDEQPLENYLDMEY 76
Query: 277 YGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQFA 456
+G I IGTP Q F VVFDTGSSNLWVPS C +++AC HN+++ S++Y + +
Sbjct: 77 FGTIGIGTPAQDFTVVFDTGSSNLWVPSVYC--SSLACTNHNRFNPEDSSTYQSTSETVS 134
Query: 457 IQYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFXTI 624
I YG+GS++G L D V VGG+ Q F + +EPG A FDGILG+A+ +I
Sbjct: 135 ITYGTGSMTGILGYDTVQVGGISDTNQIFGLSETEPGSFLYYAPFDGILGLAYPSI 190
>M26032-1|AAA60061.1| 388|Homo sapiens pepsinogen A protein.
Length = 388
Score = 135 bits (327), Expect = 1e-31
Identities = 74/176 (42%), Positives = 103/176 (58%), Gaps = 12/176 (6%)
Frame = +1
Query: 133 LYRVPLHRMKTARTHFHEVGTELELLRL-------KYDVTGPSP-----EPLSNYLDAQY 276
+Y+VPL R K+ R E G + L+ KY +P +PL NYLD +Y
Sbjct: 17 MYKVPLIRKKSFRRTLSERGLLKDFLKKHNLNPARKYFPQWKAPTLVDEQPLENYLDMEY 76
Query: 277 YGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQFA 456
+G I IGTP Q F V+FDTGSSNLWVPS C +++AC HN+++ S++Y + +
Sbjct: 77 FGTIGIGTPAQDFTVLFDTGSSNLWVPSVYC--SSLACTNHNRFNPEDSSTYQSTSETVS 134
Query: 457 IQYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFDGILGMAFXTI 624
I YG+GS++G L D V VGG+ Q F + +EPG A FDGILG+A+ +I
Sbjct: 135 ITYGTGSMTGILGYDTVQVGGISDTNQIFGLSETEPGSFLYYAPFDGILGLAYPSI 190
>X00063-1|CAA24937.1| 300|Homo sapiens protein ( Human kidney mRNA
fragment for renin (aa 105-401). ).
Length = 300
Score = 99.5 bits (237), Expect = 8e-21
Identities = 44/92 (47%), Positives = 61/92 (66%)
Frame = +1
Query: 340 SNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQFAIQYGSGSLSGFLSTDDVTVGG 519
SN+WVPS KC AC+ H +D+ S+SY NGT+ ++Y +G++SGFLS D +TVGG
Sbjct: 1 SNVWVPSSKCSRLYTACVYHKLFDASDSSSYKHNGTELTLRYSTGTVSGFLSQDIITVGG 60
Query: 520 LKVRRQTFAEAVSEPGLAFVAAKFDGILGMAF 615
+ V Q F E P L F+ A+FDG++GM F
Sbjct: 61 ITV-TQMFGEVTEMPALPFMLAEFDGVVGMGF 91
>BC014453-1|AAH14453.1| 518|Homo sapiens beta-site APP-cleaving
enzyme 2 protein.
Length = 518
Score = 61.7 bits (143), Expect = 2e-09
Identities = 38/119 (31%), Positives = 61/119 (51%), Gaps = 2/119 (1%)
Frame = +1
Query: 274 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQF 453
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S++Y + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145
Query: 454 AIQYGSGSLSGFLSTDDVTV-GGLKVRRQTFAEAVSEPGLAFV-AAKFDGILGMAFXTI 624
++Y GS +GF+ D VT+ G + E F+ K++GILG+A+ T+
Sbjct: 146 TVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLPGIKWNGILGLAYATL 204
>AY358927-1|AAQ89286.1| 518|Homo sapiens BACE2 protein.
Length = 518
Score = 61.7 bits (143), Expect = 2e-09
Identities = 38/119 (31%), Positives = 61/119 (51%), Gaps = 2/119 (1%)
Frame = +1
Query: 274 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQF 453
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S++Y + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145
Query: 454 AIQYGSGSLSGFLSTDDVTV-GGLKVRRQTFAEAVSEPGLAFV-AAKFDGILGMAFXTI 624
++Y GS +GF+ D VT+ G + E F+ K++GILG+A+ T+
Sbjct: 146 TVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLPGIKWNGILGLAYATL 204
>AF212252-1|AAG41783.1| 439|Homo sapiens CDA13 protein.
Length = 439
Score = 61.7 bits (143), Expect = 2e-09
Identities = 38/119 (31%), Positives = 61/119 (51%), Gaps = 2/119 (1%)
Frame = +1
Query: 274 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQF 453
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S++Y + G
Sbjct: 13 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 66
Query: 454 AIQYGSGSLSGFLSTDDVTV-GGLKVRRQTFAEAVSEPGLAFV-AAKFDGILGMAFXTI 624
++Y GS +GF+ D VT+ G + E F+ K++GILG+A+ T+
Sbjct: 67 TVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLPGIKWNGILGLAYATL 125
>AF204944-1|AAF26368.1| 518|Homo sapiens transmembrane aspartic
proteinase Asp 1 protein.
Length = 518
Score = 61.7 bits (143), Expect = 2e-09
Identities = 38/119 (31%), Positives = 61/119 (51%), Gaps = 2/119 (1%)
Frame = +1
Query: 274 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQF 453
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S++Y + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145
Query: 454 AIQYGSGSLSGFLSTDDVTV-GGLKVRRQTFAEAVSEPGLAFV-AAKFDGILGMAFXTI 624
++Y GS +GF+ D VT+ G + E F+ K++GILG+A+ T+
Sbjct: 146 TVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLPGIKWNGILGLAYATL 204
>AF200342-1|AAF17078.1| 518|Homo sapiens aspartyl protease 1
protein.
Length = 518
Score = 61.7 bits (143), Expect = 2e-09
Identities = 38/119 (31%), Positives = 61/119 (51%), Gaps = 2/119 (1%)
Frame = +1
Query: 274 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQF 453
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S++Y + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145
Query: 454 AIQYGSGSLSGFLSTDDVTV-GGLKVRRQTFAEAVSEPGLAFV-AAKFDGILGMAFXTI 624
++Y GS +GF+ D VT+ G + E F+ K++GILG+A+ T+
Sbjct: 146 TVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLPGIKWNGILGLAYATL 204
>AF200192-1|AAF13714.1| 518|Homo sapiens memapsin 1 protein.
Length = 518
Score = 61.7 bits (143), Expect = 2e-09
Identities = 38/119 (31%), Positives = 61/119 (51%), Gaps = 2/119 (1%)
Frame = +1
Query: 274 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQF 453
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S++Y + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145
Query: 454 AIQYGSGSLSGFLSTDDVTV-GGLKVRRQTFAEAVSEPGLAFV-AAKFDGILGMAFXTI 624
++Y GS +GF+ D VT+ G + E F+ K++GILG+A+ T+
Sbjct: 146 TVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLPGIKWNGILGLAYATL 204
>AF188277-1|AAF35836.1| 396|Homo sapiens aspartyl protease protein.
Length = 396
Score = 61.7 bits (143), Expect = 2e-09
Identities = 38/119 (31%), Positives = 61/119 (51%), Gaps = 2/119 (1%)
Frame = +1
Query: 274 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQF 453
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S++Y + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145
Query: 454 AIQYGSGSLSGFLSTDDVTV-GGLKVRRQTFAEAVSEPGLAFV-AAKFDGILGMAFXTI 624
++Y GS +GF+ D VT+ G + E F+ K++GILG+A+ T+
Sbjct: 146 TVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLPGIKWNGILGLAYATL 204
>AF188276-1|AAF35835.1| 468|Homo sapiens aspartyl protease protein.
Length = 468
Score = 61.7 bits (143), Expect = 2e-09
Identities = 38/119 (31%), Positives = 61/119 (51%), Gaps = 2/119 (1%)
Frame = +1
Query: 274 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQF 453
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S++Y + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145
Query: 454 AIQYGSGSLSGFLSTDDVTV-GGLKVRRQTFAEAVSEPGLAFV-AAKFDGILGMAFXTI 624
++Y GS +GF+ D VT+ G + E F+ K++GILG+A+ T+
Sbjct: 146 TVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLPGIKWNGILGLAYATL 204
>AF178532-1|AAF29494.1| 518|Homo sapiens aspartyl protease protein.
Length = 518
Score = 61.7 bits (143), Expect = 2e-09
Identities = 38/119 (31%), Positives = 61/119 (51%), Gaps = 2/119 (1%)
Frame = +1
Query: 274 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQF 453
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S++Y + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145
Query: 454 AIQYGSGSLSGFLSTDDVTV-GGLKVRRQTFAEAVSEPGLAFV-AAKFDGILGMAFXTI 624
++Y GS +GF+ D VT+ G + E F+ K++GILG+A+ T+
Sbjct: 146 TVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLPGIKWNGILGLAYATL 204
>AF117892-1|AAD45240.1| 518|Homo sapiens aspartic-like protease
protein.
Length = 518
Score = 61.7 bits (143), Expect = 2e-09
Identities = 38/119 (31%), Positives = 61/119 (51%), Gaps = 2/119 (1%)
Frame = +1
Query: 274 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQF 453
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S++Y + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145
Query: 454 AIQYGSGSLSGFLSTDDVTV-GGLKVRRQTFAEAVSEPGLAFV-AAKFDGILGMAFXTI 624
++Y GS +GF+ D VT+ G + E F+ K++GILG+A+ T+
Sbjct: 146 TVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLPGIKWNGILGLAYATL 204
>AF050171-1|AAD45963.1| 518|Homo sapiens aspartyl protease protein.
Length = 518
Score = 61.7 bits (143), Expect = 2e-09
Identities = 38/119 (31%), Positives = 61/119 (51%), Gaps = 2/119 (1%)
Frame = +1
Query: 274 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQF 453
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S++Y + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145
Query: 454 AIQYGSGSLSGFLSTDDVTV-GGLKVRRQTFAEAVSEPGLAFV-AAKFDGILGMAFXTI 624
++Y GS +GF+ D VT+ G + E F+ K++GILG+A+ T+
Sbjct: 146 TVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLPGIKWNGILGLAYATL 204
>AK075539-1|BAC11682.1| 423|Homo sapiens protein ( Homo sapiens
cDNA PSEC0239 fis, clone OVARC1000363, highly similar to
Homo sapiens aspartyl protease mRNA. ).
Length = 423
Score = 60.5 bits (140), Expect = 5e-09
Identities = 36/113 (31%), Positives = 59/113 (52%), Gaps = 2/113 (1%)
Frame = +1
Query: 292 IGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQFAIQYGS 471
IGTPPQ +++ DTGSSN V Y + +D+ +S++Y + G ++Y
Sbjct: 3 IGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDVTVKYTQ 56
Query: 472 GSLSGFLSTDDVTV-GGLKVRRQTFAEAVSEPGLAFV-AAKFDGILGMAFXTI 624
GS +GF+ D VT+ G + E G F+ +++GILG+A+ T+
Sbjct: 57 GSWTGFVGEDLVTIPKGFNTSFLVNIATIFESGNFFLPGIQWNGILGLAYATL 109
>BC042578-1|AAH42578.1| 104|Homo sapiens PGC protein protein.
Length = 104
Score = 60.1 bits (139), Expect = 6e-09
Identities = 38/82 (46%), Positives = 49/82 (59%), Gaps = 9/82 (10%)
Frame = +1
Query: 130 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 282
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 17 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 75
Query: 283 VISIGTPPQSFKVVFDTGSSNL 348
ISIGTPPQ+F V+FDTGSS L
Sbjct: 76 EISIGTPPQNFLVLFDTGSSPL 97
>DQ007053-1|AAY16982.1| 501|Homo sapiens beta-site APP-cleaving
enzyme 1 protein.
Length = 501
Score = 53.2 bits (122), Expect = 7e-07
Identities = 36/119 (30%), Positives = 60/119 (50%), Gaps = 2/119 (1%)
Frame = +1
Query: 274 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQF 453
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S++Y
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 454 AIQYGSGSLSGFLSTDDVTV-GGLKVRRQTFAEAVSEPGLAFV-AAKFDGILGMAFXTI 624
+ Y G G L TD V++ G V + A++E F+ + ++GILG+A+ I
Sbjct: 129 YVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEI 187
>BC065492-1|AAH65492.1| 501|Homo sapiens beta-site APP-cleaving
enzyme 1 protein.
Length = 501
Score = 53.2 bits (122), Expect = 7e-07
Identities = 36/119 (30%), Positives = 60/119 (50%), Gaps = 2/119 (1%)
Frame = +1
Query: 274 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQF 453
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S++Y
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 454 AIQYGSGSLSGFLSTDDVTV-GGLKVRRQTFAEAVSEPGLAFV-AAKFDGILGMAFXTI 624
+ Y G G L TD V++ G V + A++E F+ + ++GILG+A+ I
Sbjct: 129 YVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEI 187
>AF338816-1|AAK38374.1| 476|Homo sapiens beta-site APP cleaving
enzyme type B protein.
Length = 476
Score = 53.2 bits (122), Expect = 7e-07
Identities = 36/119 (30%), Positives = 60/119 (50%), Gaps = 2/119 (1%)
Frame = +1
Query: 274 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQF 453
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S++Y
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 454 AIQYGSGSLSGFLSTDDVTV-GGLKVRRQTFAEAVSEPGLAFV-AAKFDGILGMAFXTI 624
+ Y G G L TD V++ G V + A++E F+ + ++GILG+A+ I
Sbjct: 129 YVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEI 187
>AF204943-1|AAF26367.1| 501|Homo sapiens transmembrane aspartic
proteinase Asp 2 protein.
Length = 501
Score = 53.2 bits (122), Expect = 7e-07
Identities = 36/119 (30%), Positives = 60/119 (50%), Gaps = 2/119 (1%)
Frame = +1
Query: 274 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQF 453
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S++Y
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 454 AIQYGSGSLSGFLSTDDVTV-GGLKVRRQTFAEAVSEPGLAFV-AAKFDGILGMAFXTI 624
+ Y G G L TD V++ G V + A++E F+ + ++GILG+A+ I
Sbjct: 129 YVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEI 187
>AF201468-1|AAF18982.1| 501|Homo sapiens APP beta-secretase
protein.
Length = 501
Score = 53.2 bits (122), Expect = 7e-07
Identities = 36/119 (30%), Positives = 60/119 (50%), Gaps = 2/119 (1%)
Frame = +1
Query: 274 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQF 453
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S++Y
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 454 AIQYGSGSLSGFLSTDDVTV-GGLKVRRQTFAEAVSEPGLAFV-AAKFDGILGMAFXTI 624
+ Y G G L TD V++ G V + A++E F+ + ++GILG+A+ I
Sbjct: 129 YVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEI 187
>AF200343-1|AAF17079.1| 501|Homo sapiens aspartyl protease 2
protein.
Length = 501
Score = 53.2 bits (122), Expect = 7e-07
Identities = 36/119 (30%), Positives = 60/119 (50%), Gaps = 2/119 (1%)
Frame = +1
Query: 274 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQF 453
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S++Y
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 454 AIQYGSGSLSGFLSTDDVTV-GGLKVRRQTFAEAVSEPGLAFV-AAKFDGILGMAFXTI 624
+ Y G G L TD V++ G V + A++E F+ + ++GILG+A+ I
Sbjct: 129 YVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEI 187
>AF200193-1|AAF13715.1| 488|Homo sapiens memapsin 2 protein.
Length = 488
Score = 53.2 bits (122), Expect = 7e-07
Identities = 36/119 (30%), Positives = 60/119 (50%), Gaps = 2/119 (1%)
Frame = +1
Query: 274 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQF 453
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S++Y
Sbjct: 62 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 115
Query: 454 AIQYGSGSLSGFLSTDDVTV-GGLKVRRQTFAEAVSEPGLAFV-AAKFDGILGMAFXTI 624
+ Y G G L TD V++ G V + A++E F+ + ++GILG+A+ I
Sbjct: 116 YVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEI 174
>AF190725-1|AAF04142.1| 501|Homo sapiens beta-site APP cleaving
enzyme protein.
Length = 501
Score = 53.2 bits (122), Expect = 7e-07
Identities = 36/119 (30%), Positives = 60/119 (50%), Gaps = 2/119 (1%)
Frame = +1
Query: 274 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQF 453
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S++Y
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 454 AIQYGSGSLSGFLSTDDVTV-GGLKVRRQTFAEAVSEPGLAFV-AAKFDGILGMAFXTI 624
+ Y G G L TD V++ G V + A++E F+ + ++GILG+A+ I
Sbjct: 129 YVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEI 187
>AB050436-1|BAB40931.1| 476|Homo sapiens beta-site APP cleaving
enzyme I-476 protein.
Length = 476
Score = 53.2 bits (122), Expect = 7e-07
Identities = 36/119 (30%), Positives = 60/119 (50%), Gaps = 2/119 (1%)
Frame = +1
Query: 274 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQF 453
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S++Y
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 454 AIQYGSGSLSGFLSTDDVTV-GGLKVRRQTFAEAVSEPGLAFV-AAKFDGILGMAFXTI 624
+ Y G G L TD V++ G V + A++E F+ + ++GILG+A+ I
Sbjct: 129 YVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEI 187
>AB032975-1|BAA86463.2| 532|Homo sapiens KIAA1149 protein protein.
Length = 532
Score = 53.2 bits (122), Expect = 7e-07
Identities = 36/119 (30%), Positives = 60/119 (50%), Gaps = 2/119 (1%)
Frame = +1
Query: 274 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQF 453
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S++Y
Sbjct: 106 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 159
Query: 454 AIQYGSGSLSGFLSTDDVTV-GGLKVRRQTFAEAVSEPGLAFV-AAKFDGILGMAFXTI 624
+ Y G G L TD V++ G V + A++E F+ + ++GILG+A+ I
Sbjct: 160 YVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEI 218
>BC036084-1|AAH36084.1| 501|Homo sapiens beta-site APP-cleaving
enzyme 1 protein.
Length = 501
Score = 50.8 bits (116), Expect = 4e-06
Identities = 35/119 (29%), Positives = 59/119 (49%), Gaps = 2/119 (1%)
Frame = +1
Query: 274 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQF 453
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + ++Y
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLFSTYRDLRKGV 128
Query: 454 AIQYGSGSLSGFLSTDDVTV-GGLKVRRQTFAEAVSEPGLAFV-AAKFDGILGMAFXTI 624
+ Y G G L TD V++ G V + A++E F+ + ++GILG+A+ I
Sbjct: 129 YVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEI 187
>AL163285-1|CAB90554.1| 415|Homo sapiens beta-site APP-cleaving
enzyme 2, EC 3.4.23. protein.
Length = 415
Score = 45.2 bits (102), Expect = 2e-04
Identities = 30/105 (28%), Positives = 52/105 (49%), Gaps = 2/105 (1%)
Frame = +1
Query: 316 KVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQFAIQYGSGSLSGFLS 495
+++ DTGSSN V Y + +D+ +S++Y + G ++Y GS +GF+
Sbjct: 3 QILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDVTVKYTQGSWTGFVG 56
Query: 496 TDDVTV-GGLKVRRQTFAEAVSEPGLAFV-AAKFDGILGMAFXTI 624
D VT+ G + E F+ K++GILG+A+ T+
Sbjct: 57 EDLVTIPKGFNTSFLVNIATIFESENFFLPGIKWNGILGLAYATL 101
>AB050438-1|BAB40933.1| 432|Homo sapiens beta-site APP cleaving
enzyme I-432 protein.
Length = 432
Score = 41.1 bits (92), Expect = 0.003
Identities = 26/94 (27%), Positives = 43/94 (45%)
Frame = +1
Query: 274 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQF 453
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S++Y
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 454 AIQYGSGSLSGFLSTDDVTVGGLKVRRQTFAEAV 555
+ Y G G L TD + G + + +V
Sbjct: 129 YVPYTQGKWEGELGTDLLCGAGFPLNQSEVLASV 162
>AF338817-1|AAK38375.1| 457|Homo sapiens beta-site APP cleaving
enzyme type C protein.
Length = 457
Score = 40.7 bits (91), Expect = 0.004
Identities = 24/76 (31%), Positives = 37/76 (48%)
Frame = +1
Query: 274 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQF 453
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S++Y
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 454 AIQYGSGSLSGFLSTD 501
+ Y G G L TD
Sbjct: 129 YVPYTQGKWEGELGTD 144
>AB050437-1|BAB40932.1| 457|Homo sapiens beta-site APP cleaving
enzyme I-457 protein.
Length = 457
Score = 40.7 bits (91), Expect = 0.004
Identities = 24/76 (31%), Positives = 37/76 (48%)
Frame = +1
Query: 274 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQF 453
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S++Y
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 454 AIQYGSGSLSGFLSTD 501
+ Y G G L TD
Sbjct: 129 YVPYTQGKWEGELGTD 144
>AL365205-3|CAM16152.1| 86|Homo sapiens progastricsin (pepsinogen
C) protein.
Length = 86
Score = 38.3 bits (85), Expect = 0.022
Identities = 28/69 (40%), Positives = 36/69 (52%), Gaps = 9/69 (13%)
Frame = +1
Query: 124 VMALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQY 276
V+ RVPL + K+ R E G E LR KYD + EP++ Y+DA Y
Sbjct: 19 VICKQRVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAY 77
Query: 277 YGVISIGTP 303
+G ISIGTP
Sbjct: 78 FGEISIGTP 86
>AL365205-2|CAI95135.1| 140|Homo sapiens progastricsin (pepsinogen
C) protein.
Length = 140
Score = 36.7 bits (81), Expect = 0.067
Identities = 16/35 (45%), Positives = 24/35 (68%)
Frame = +1
Query: 511 VGGLKVRRQTFAEAVSEPGLAFVAAKFDGILGMAF 615
V ++V Q F + +EPG FV A+FDGI+G+A+
Sbjct: 71 VQSIQVPNQEFGLSENEPGTNFVYAQFDGIMGLAY 105
>AB089958-1|BAC81826.1| 127|Homo sapiens beta-site APP cleaving
enzyme isoform I-127 protein.
Length = 127
Score = 35.5 bits (78), Expect = 0.15
Identities = 18/53 (33%), Positives = 30/53 (56%)
Frame = +1
Query: 274 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSY 432
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S++Y
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTY 121
>BC030606-1|AAH30606.2| 514|Homo sapiens coiled-coil domain
containing 11 protein.
Length = 514
Score = 32.7 bits (71), Expect = 1.1
Identities = 13/26 (50%), Positives = 18/26 (69%)
Frame = -2
Query: 339 GSGVEYHLERLRRRADTDNSVVLSIK 262
G G E+HLER+RR N+++ SIK
Sbjct: 30 GQGAEHHLERIRRSHQKHNAILASIK 55
>BC104851-1|AAI04852.1| 147|Homo sapiens LOC283174 protein protein.
Length = 147
Score = 31.1 bits (67), Expect = 3.3
Identities = 20/75 (26%), Positives = 32/75 (42%)
Frame = +1
Query: 331 TGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQFAIQYGSGSLSGFLSTDDVT 510
T + LW + + C L N S+ TS++ G+ Q S S FL+ ++
Sbjct: 7 THNGRLWGAGVHLYLSRKQCALKNTSLSKFQTSHICKGSALQPQQASPGASSFLTCPELG 66
Query: 511 VGGLKVRRQTFAEAV 555
V LK+ +AV
Sbjct: 67 VMYLKLVLGQMVQAV 81
>BC101691-1|AAI01692.1| 147|Homo sapiens LOC283174 protein protein.
Length = 147
Score = 31.1 bits (67), Expect = 3.3
Identities = 20/75 (26%), Positives = 32/75 (42%)
Frame = +1
Query: 331 TGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQFAIQYGSGSLSGFLSTDDVT 510
T + LW + + C L N S+ TS++ G+ Q S S FL+ ++
Sbjct: 7 THNGRLWGAGVHLYLSRKQCALKNTSLSKFQTSHICKGSALQPQQASPGASSFLTCPELG 66
Query: 511 VGGLKVRRQTFAEAV 555
V LK+ +AV
Sbjct: 67 VMYLKLVLGQMVQAV 81
>X85133-1|CAA59445.1| 948|Homo sapiens RB protein binding protein
protein.
Length = 948
Score = 29.9 bits (64), Expect = 7.6
Identities = 16/46 (34%), Positives = 21/46 (45%)
Frame = -3
Query: 605 PRIPSNLAATKASPGSDTASANVWRRTLSPPTVTSSVERKPERLPE 468
P P+NL+ S G TA +N T +PP R+ RL E
Sbjct: 429 PPAPANLSTPWVSSGVQTAHSNTIPTTQAPPLSREEFYREQRRLKE 474
>BC041063-1|AAH41063.1| 616|Homo sapiens eyes absent homolog 4
(Drosophila) protein.
Length = 616
Score = 29.9 bits (64), Expect = 7.6
Identities = 30/101 (29%), Positives = 40/101 (39%), Gaps = 1/101 (0%)
Frame = +1
Query: 295 GTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKS-TSYVANGTQFAIQYGS 471
G P S+++ GSS + PS + N N S++ SY A G QY S
Sbjct: 209 GQTPYSYQM---PGSS--FAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYS 263
Query: 472 GSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFD 594
S G T + T G T+ S PGL +FD
Sbjct: 264 ASTYGAYMTSNNTADGTPSSTSTYQLQESLPGLTNQPGEFD 304
>AY072922-1|AAL68925.1| 1625|Homo sapiens p53-associated cellular
protein PACT protein.
Length = 1625
Score = 29.9 bits (64), Expect = 7.6
Identities = 16/46 (34%), Positives = 21/46 (45%)
Frame = -3
Query: 605 PRIPSNLAATKASPGSDTASANVWRRTLSPPTVTSSVERKPERLPE 468
P P+NL+ S G TA +N T +PP R+ RL E
Sbjct: 472 PPAPANLSTPWVSSGVQTAHSNTIPTTQAPPLSREEFYREQRRLKE 517
>AL450270-3|CAI41273.1| 605|Homo sapiens eyes absent homolog 4
(Drosophila) protein.
Length = 605
Score = 29.9 bits (64), Expect = 7.6
Identities = 30/101 (29%), Positives = 40/101 (39%), Gaps = 1/101 (0%)
Frame = +1
Query: 295 GTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKS-TSYVANGTQFAIQYGS 471
G P S+++ GSS + PS + N N S++ SY A G QY S
Sbjct: 198 GQTPYSYQM---PGSS--FAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYS 252
Query: 472 GSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFD 594
S G T + T G T+ S PGL +FD
Sbjct: 253 ASTYGAYMTSNNTADGTPSSTSTYQLQESLPGLTNQPGEFD 293
>AL450270-2|CAI41272.1| 639|Homo sapiens eyes absent homolog 4
(Drosophila) protein.
Length = 639
Score = 29.9 bits (64), Expect = 7.6
Identities = 30/101 (29%), Positives = 40/101 (39%), Gaps = 1/101 (0%)
Frame = +1
Query: 295 GTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKS-TSYVANGTQFAIQYGS 471
G P S+++ GSS + PS + N N S++ SY A G QY S
Sbjct: 232 GQTPYSYQM---PGSS--FAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYS 286
Query: 472 GSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFD 594
S G T + T G T+ S PGL +FD
Sbjct: 287 ASTYGAYMTSNNTADGTPSSTSTYQLQESLPGLTNQPGEFD 327
>AL121959-1|CAB92069.2| 639|Homo sapiens eyes absent homolog 4
(Drosophila) protein.
Length = 639
Score = 29.9 bits (64), Expect = 7.6
Identities = 30/101 (29%), Positives = 40/101 (39%), Gaps = 1/101 (0%)
Frame = +1
Query: 295 GTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKS-TSYVANGTQFAIQYGS 471
G P S+++ GSS + PS + N N S++ SY A G QY S
Sbjct: 232 GQTPYSYQM---PGSS--FAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYS 286
Query: 472 GSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFD 594
S G T + T G T+ S PGL +FD
Sbjct: 287 ASTYGAYMTSNNTADGTPSSTSTYQLQESLPGLTNQPGEFD 327
>AL024497-3|CAI42525.1| 605|Homo sapiens eyes absent homolog 4
(Drosophila) protein.
Length = 605
Score = 29.9 bits (64), Expect = 7.6
Identities = 30/101 (29%), Positives = 40/101 (39%), Gaps = 1/101 (0%)
Frame = +1
Query: 295 GTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKS-TSYVANGTQFAIQYGS 471
G P S+++ GSS + PS + N N S++ SY A G QY S
Sbjct: 198 GQTPYSYQM---PGSS--FAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYS 252
Query: 472 GSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFD 594
S G T + T G T+ S PGL +FD
Sbjct: 253 ASTYGAYMTSNNTADGTPSSTSTYQLQESLPGLTNQPGEFD 293
>AL024497-2|CAI42524.1| 639|Homo sapiens eyes absent homolog 4
(Drosophila) protein.
Length = 639
Score = 29.9 bits (64), Expect = 7.6
Identities = 30/101 (29%), Positives = 40/101 (39%), Gaps = 1/101 (0%)
Frame = +1
Query: 295 GTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKS-TSYVANGTQFAIQYGS 471
G P S+++ GSS + PS + N N S++ SY A G QY S
Sbjct: 232 GQTPYSYQM---PGSS--FAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYS 286
Query: 472 GSLSGFLSTDDVTVGGLKVRRQTFAEAVSEPGLAFVAAKFD 594
S G T + T G T+ S PGL +FD
Sbjct: 287 ASTYGAYMTSNNTADGTPSSTSTYQLQESLPGLTNQPGEFD 327
>AF352051-1|AAL05625.1| 1616|Homo sapiens proliferation
potential-related protein protein.
Length = 1616
Score = 29.9 bits (64), Expect = 7.6
Identities = 16/46 (34%), Positives = 21/46 (45%)
Frame = -3
Query: 605 PRIPSNLAATKASPGSDTASANVWRRTLSPPTVTSSVERKPERLPE 468
P P+NL+ S G TA +N T +PP R+ RL E
Sbjct: 429 PPAPANLSTPWVSSGVQTAHSNTIPTTQAPPLSREEFYREQRRLKE 474
>AB112075-1|BAC77637.1| 1758|Homo sapiens retinoblastoma binding
protein 6 isoform 2 protein.
Length = 1758
Score = 29.9 bits (64), Expect = 7.6
Identities = 16/46 (34%), Positives = 21/46 (45%)
Frame = -3
Query: 605 PRIPSNLAATKASPGSDTASANVWRRTLSPPTVTSSVERKPERLPE 468
P P+NL+ S G TA +N T +PP R+ RL E
Sbjct: 605 PPAPANLSTPWVSSGVQTAHSNTIPTTQAPPLSREEFYREQRRLKE 650
>AB112074-1|BAC77636.1| 1792|Homo sapiens retinoblastoma binding
protein 6 isoform 1 protein.
Length = 1792
Score = 29.9 bits (64), Expect = 7.6
Identities = 16/46 (34%), Positives = 21/46 (45%)
Frame = -3
Query: 605 PRIPSNLAATKASPGSDTASANVWRRTLSPPTVTSSVERKPERLPE 468
P P+NL+ S G TA +N T +PP R+ RL E
Sbjct: 605 PPAPANLSTPWVSSGVQTAHSNTIPTTQAPPLSREEFYREQRRLKE 650
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 85,641,102
Number of Sequences: 237096
Number of extensions: 1806898
Number of successful extensions: 4941
Number of sequences better than 10.0: 84
Number of HSP's better than 10.0 without gapping: 4527
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4863
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 6747805200
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
- SilkBase 1999-2023 -