Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P15_F_C21
(778 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_UPI000065D235 Cluster: Histone deacetylase 1 (HD1).; n=... 348 8e-95
UniRef50_Q13547 Cluster: Histone deacetylase 1; n=60; Fungi/Meta... 347 2e-94
UniRef50_Q92769 Cluster: Histone deacetylase 2; n=50; Eukaryota|... 346 3e-94
UniRef50_Q9HDT2 Cluster: Histone deacetylase; n=4; Fungi/Metazoa... 268 1e-70
UniRef50_A3BWV6 Cluster: Putative uncharacterized protein; n=2; ... 258 8e-68
UniRef50_O15379 Cluster: Histone deacetylase 3; n=149; Eukaryota... 256 4e-67
UniRef50_A2FDZ0 Cluster: Acetylpolyamine aminohydrolase, putativ... 239 4e-62
UniRef50_Q5KKR8 Cluster: Histone deacetylase 1-1 (Hd1), putative... 209 2e-61
UniRef50_Q4WHY0 Cluster: Histone deacetylase HosA; n=15; Fungi/M... 233 4e-60
UniRef50_Q5U8M9 Cluster: Histone deacetylase 1; n=2; Entamoeba h... 230 3e-59
UniRef50_Q5XTS3 Cluster: Histone deacetylase HDAC; n=2; Giardia ... 221 1e-56
UniRef50_P53096 Cluster: Probable histone deacetylase HOS2; n=15... 220 4e-56
UniRef50_Q09440 Cluster: Putative histone deacetylase 2; n=2; Ca... 215 8e-55
UniRef50_A4RK28 Cluster: Putative uncharacterized protein; n=1; ... 211 1e-53
UniRef50_A0DPM0 Cluster: Chromosome undetermined scaffold_59, wh... 205 1e-51
UniRef50_Q0V6A5 Cluster: Putative uncharacterized protein; n=2; ... 192 8e-48
UniRef50_A4VDD9 Cluster: Histone deacetylase 1, 2 ,3; n=4; Oligo... 192 1e-47
UniRef50_A0PAD5 Cluster: Putative uncharacterized protein; n=2; ... 182 9e-45
UniRef50_Q94D35 Cluster: Histone deacetylase-like; n=9; Oryza sa... 173 5e-42
UniRef50_A0CXG2 Cluster: Chromosome undetermined scaffold_30, wh... 171 1e-41
UniRef50_UPI0000587266 Cluster: PREDICTED: similar to Histone de... 164 2e-39
UniRef50_Q9BY41 Cluster: Histone deacetylase 8; n=40; Eumetazoa|... 163 6e-39
UniRef50_A3C9I4 Cluster: Putative uncharacterized protein; n=6; ... 157 4e-37
UniRef50_UPI0000D55D9C Cluster: PREDICTED: similar to histone de... 150 3e-35
UniRef50_Q8SQN9 Cluster: HISTONE DEACETYLASE; n=1; Encephalitozo... 150 3e-35
UniRef50_Q4QCE7 Cluster: Histone deacetylase, putative; n=7; Try... 150 4e-35
UniRef50_Q98RL4 Cluster: Histone deacetylase; n=1; Guillardia th... 149 8e-35
UniRef50_Q4QAJ4 Cluster: Histone deacetylase, putative; n=3; Lei... 149 1e-34
UniRef50_Q17CU3 Cluster: Histone deacetylase; n=2; Aedes aegypti... 144 2e-33
UniRef50_Q6C3Y5 Cluster: Similar to CA1453|CaHOS1 Candida albica... 137 3e-31
UniRef50_Q74DU3 Cluster: Histone deacetylase/AcuC/AphA family pr... 130 3e-29
UniRef50_A0B926 Cluster: Histone deacetylase superfamily; n=1; M... 127 3e-28
UniRef50_Q3A415 Cluster: Deacetylase; n=1; Pelobacter carbinolic... 123 6e-27
UniRef50_A5DN16 Cluster: Putative uncharacterized protein; n=1; ... 120 3e-26
UniRef50_A5H660 Cluster: Histone deacetylase 8; n=3; Schistosoma... 120 4e-26
UniRef50_A0K0A0 Cluster: Histone deacetylase superfamily; n=2; A... 119 9e-26
UniRef50_P39067 Cluster: Acetoin utilization protein acuC; n=25;... 117 3e-25
UniRef50_Q0S1K3 Cluster: Possible acetoin dehydrogenase; n=3; Ba... 117 4e-25
UniRef50_Q6BS96 Cluster: Similar to CA1453|CaHOS1 Candida albica... 113 5e-24
UniRef50_Q4R7V0 Cluster: Testis cDNA clone: QtsA-14323, similar ... 112 1e-23
UniRef50_O67135 Cluster: Acetoin utilization protein; n=2; Aquif... 109 8e-23
UniRef50_Q4P6M9 Cluster: Putative uncharacterized protein; n=1; ... 87 8e-23
UniRef50_UPI000050FC36 Cluster: COG0123: Deacetylases, including... 107 3e-22
UniRef50_P64375 Cluster: Acetoin utilization protein acuC; n=15;... 107 3e-22
UniRef50_Q1AX98 Cluster: Histone deacetylase superfamily; n=2; B... 105 2e-21
UniRef50_A7TRW5 Cluster: Putative uncharacterized protein; n=1; ... 104 2e-21
UniRef50_Q12214 Cluster: Histone deacetylase HOS1; n=2; Saccharo... 104 2e-21
UniRef50_Q2J786 Cluster: Histone deacetylase superfamily; n=13; ... 103 7e-21
UniRef50_Q6CVU3 Cluster: Similar to sp|Q12214 Saccharomyces cere... 102 9e-21
UniRef50_Q6FWB7 Cluster: Similar to sp|Q12214 Saccharomyces cere... 101 2e-20
UniRef50_Q59Q78 Cluster: Likely histone deacetylase Hos1p; n=2; ... 101 3e-20
UniRef50_Q75BA6 Cluster: ADL339Wp; n=1; Eremothecium gossypii|Re... 100 4e-20
UniRef50_Q2S035 Cluster: Acetoin utilization protein acuC; n=4; ... 91 3e-17
UniRef50_Q981B8 Cluster: Acetylpolyamine aminohydrolase; n=4; Su... 91 3e-17
UniRef50_Q381M6 Cluster: Histone deacetylase 2; n=4; Trypanosoma... 90 5e-17
UniRef50_O30107 Cluster: Uncharacterized protein AF_0130; n=2; E... 86 8e-16
UniRef50_A5E4H2 Cluster: Putative uncharacterized protein; n=1; ... 83 1e-14
UniRef50_A0L9T2 Cluster: Histone deacetylase superfamily; n=3; P... 81 3e-14
UniRef50_Q7VZF1 Cluster: Histone deacetylase family protein; n=6... 77 7e-13
UniRef50_Q64AZ9 Cluster: Deacetylase; n=1; uncultured archaeon G... 77 7e-13
UniRef50_Q0LS19 Cluster: Histone deacetylase superfamily; n=1; C... 76 9e-13
UniRef50_Q1H193 Cluster: Histone deacetylase superfamily; n=2; B... 76 1e-12
UniRef50_O88895-2 Cluster: Isoform Short of O88895 ; n=6; Eutele... 75 2e-12
UniRef50_Q28M71 Cluster: Histone deacetylase superfamily; n=15; ... 75 2e-12
UniRef50_UPI0000DB73BE Cluster: PREDICTED: similar to HDAC6 CG61... 75 3e-12
UniRef50_A5D0K9 Cluster: Deacetylases; n=1; Pelotomaculum thermo... 74 5e-12
UniRef50_Q8IR37 Cluster: CG6170-PC, isoform C; n=7; Diptera|Rep:... 73 6e-12
UniRef50_Q17MD0 Cluster: Histone deacetylase; n=1; Aedes aegypti... 73 6e-12
UniRef50_Q7NRU4 Cluster: Histone deacetylase; n=54; Proteobacter... 73 8e-12
UniRef50_A3JCC1 Cluster: Deacetylases, including yeast histone d... 73 8e-12
UniRef50_A1RXP5 Cluster: Histone deacetylase superfamily; n=1; T... 73 1e-11
UniRef50_Q803K0 Cluster: Zgc:55652; n=4; Danio rerio|Rep: Zgc:55... 72 2e-11
UniRef50_Q5K8L3 Cluster: Histone deacetylase 3, putative; n=2; F... 71 3e-11
UniRef50_Q97Z24 Cluster: Acetoin utilization protein; n=3; Sulfo... 71 3e-11
UniRef50_Q57ET7 Cluster: Histone deacetylase family protein; n=3... 70 6e-11
UniRef50_Q02A43 Cluster: Histone deacetylase superfamily; n=1; S... 70 6e-11
UniRef50_Q2S0V9 Cluster: Histone deacetylase/AcuC/AphA family pr... 70 7e-11
UniRef50_A6ND61 Cluster: Uncharacterized protein HDAC8; n=3; Sim... 69 1e-10
UniRef50_Q569T0 Cluster: MGC115178 protein; n=5; Tetrapoda|Rep: ... 68 3e-10
UniRef50_A0IVC2 Cluster: Histone deacetylase superfamily; n=5; P... 67 4e-10
UniRef50_Q9K0J2 Cluster: Histone deacetylase family protein; n=4... 67 5e-10
UniRef50_Q2LVD3 Cluster: Histone deacetylase family protein; n=1... 67 5e-10
UniRef50_UPI00015BAE44 Cluster: histone deacetylase superfamily;... 66 7e-10
UniRef50_Q12GF8 Cluster: Histone deacetylase superfamily; n=6; B... 66 7e-10
UniRef50_P53973 Cluster: Histone deacetylase HDA1; n=7; Saccharo... 66 7e-10
UniRef50_A4JTS4 Cluster: Histone deacetylase superfamily; n=3; B... 66 9e-10
UniRef50_UPI00015BB127 Cluster: histone deacetylase superfamily;... 66 1e-09
UniRef50_Q6AKN4 Cluster: Putative uncharacterized protein; n=1; ... 65 2e-09
UniRef50_Q94EJ2 Cluster: Histone deacetylase 8; n=14; Magnolioph... 65 2e-09
UniRef50_A0Y3M1 Cluster: Histone deacetylase family protein; n=1... 65 2e-09
UniRef50_Q015Q9 Cluster: Histone deacetylase HDA110 isoform 2; n... 65 2e-09
UniRef50_Q9UBN7 Cluster: Histone deacetylase 6; n=38; Eutheria|R... 65 2e-09
UniRef50_Q1PVG5 Cluster: Similar to histone deacetylase; n=1; Ca... 64 3e-09
UniRef50_Q7XAX9 Cluster: HDA1; n=3; Magnoliophyta|Rep: HDA1 - Ze... 64 3e-09
UniRef50_A3CT27 Cluster: Histone deacetylase superfamily; n=2; M... 64 3e-09
UniRef50_P28606 Cluster: Uncharacterized 34.1 kDa protein in gln... 64 3e-09
UniRef50_UPI0000F2E91A Cluster: PREDICTED: similar to histone de... 64 5e-09
UniRef50_A3JH86 Cluster: Deacetylase / probable acetylpolyamine ... 64 5e-09
UniRef50_UPI0000D56143 Cluster: PREDICTED: similar to CG6170-PA,... 63 9e-09
UniRef50_Q5QWS4 Cluster: Histone deacetylase/AcuC/AphA family pr... 62 1e-08
UniRef50_Q18477 Cluster: Putative uncharacterized protein; n=2; ... 62 1e-08
UniRef50_A6FY71 Cluster: Histone deacetylase superfamily protein... 62 2e-08
UniRef50_Q7RB89 Cluster: Histone deacetylase/AcuC/AphA family pr... 62 2e-08
UniRef50_Q7U7V3 Cluster: Putative histone deacetylase/AcuC/AphA ... 62 2e-08
UniRef50_Q0LE47 Cluster: Histone deacetylase superfamily; n=1; H... 62 2e-08
UniRef50_Q8RX28 Cluster: Histone deacetylase 5; n=4; Magnoliophy... 62 2e-08
UniRef50_A4YNH4 Cluster: Acetylpolyamine aminohydrolase; n=15; P... 61 3e-08
UniRef50_Q23M98 Cluster: Histone deacetylase family protein; n=1... 61 3e-08
UniRef50_Q5KL48 Cluster: Histone deacetylase clr3, putative; n=1... 61 3e-08
UniRef50_UPI0001555A7F Cluster: PREDICTED: similar to histone de... 61 3e-08
UniRef50_Q8F254 Cluster: Histone deacetylase family protein; n=4... 61 3e-08
UniRef50_Q62HN7 Cluster: Acetylpolyamine aminohydrolase; n=53; P... 61 3e-08
UniRef50_Q4FNF7 Cluster: Histone deacetylase family protein; n=5... 61 3e-08
UniRef50_Q22CW6 Cluster: Histone deacetylase family protein; n=1... 61 3e-08
UniRef50_Q7Z8L6 Cluster: Putative histone deacetylase; n=2; Pleo... 60 5e-08
UniRef50_A5DRS6 Cluster: Histone deacetylase HDA1; n=7; Saccharo... 60 5e-08
UniRef50_Q08BS8 Cluster: Zgc:152701; n=9; Euteleostomi|Rep: Zgc:... 60 6e-08
UniRef50_Q8D858 Cluster: Histone deacetylase/AcuC/AphA family pr... 60 6e-08
UniRef50_Q63YT0 Cluster: Histone deacetylase family protein; n=1... 60 6e-08
UniRef50_A3JI99 Cluster: Putative aminohydrolase; n=1; Marinobac... 60 6e-08
UniRef50_Q6C4P0 Cluster: Similar to sp|P53973 Saccharomyces cere... 60 6e-08
UniRef50_UPI000069F4DB Cluster: Histone deacetylase 7a (HD7a).; ... 60 8e-08
UniRef50_Q02CA3 Cluster: Histone deacetylase superfamily; n=1; S... 60 8e-08
UniRef50_A7HFZ2 Cluster: Histone deacetylase superfamily; n=4; C... 60 8e-08
UniRef50_A1C5E8 Cluster: Histone deacetylase hda1; n=8; Eurotiom... 60 8e-08
UniRef50_Q5LRW9 Cluster: Acetylpolyamine aminohydrolase; n=7; Rh... 59 1e-07
UniRef50_Q5LQF5 Cluster: Histone deacetylase/AcuC/AphA family pr... 59 1e-07
UniRef50_Q1IMW0 Cluster: Histone deacetylase superfamily; n=2; A... 59 1e-07
UniRef50_A4BCK9 Cluster: Deacetylase, including yeast histone de... 59 1e-07
UniRef50_Q4PCR1 Cluster: Putative uncharacterized protein; n=1; ... 59 1e-07
UniRef50_Q31HC2 Cluster: Histone deacetylase family protein; n=1... 58 2e-07
UniRef50_Q15WQ0 Cluster: Histone deacetylase superfamily; n=3; G... 58 2e-07
UniRef50_A5W9E9 Cluster: Histone deacetylase superfamily; n=17; ... 58 2e-07
UniRef50_Q17I08 Cluster: Histone deacetylase; n=1; Aedes aegypti... 58 2e-07
UniRef50_Q0W553 Cluster: Putative acetoin utilization protein; n... 58 3e-07
UniRef50_Q4SMC8 Cluster: Chromosome 3 SCAF14553, whole genome sh... 57 4e-07
UniRef50_Q1IJP8 Cluster: Histone deacetylase superfamily; n=1; A... 57 4e-07
UniRef50_Q09C86 Cluster: Histone deacetylase/AcuC/AphA family pr... 57 4e-07
UniRef50_Q64BV4 Cluster: Acetoin utilization protein; n=5; Archa... 57 4e-07
UniRef50_UPI0000E463DB Cluster: PREDICTED: similar to histone de... 57 6e-07
UniRef50_Q3ZWU5 Cluster: Histone deacetylase family protein; n=3... 57 6e-07
UniRef50_Q9A2B7 Cluster: Histone deacetylase family protein; n=9... 56 7e-07
UniRef50_Q7ZYF0 Cluster: Hdac6-prov protein; n=2; Xenopus|Rep: H... 56 1e-06
UniRef50_Q00U49 Cluster: Histone deacetylase superfamily; n=3; O... 56 1e-06
UniRef50_A6SGS8 Cluster: Putative uncharacterized protein; n=3; ... 56 1e-06
UniRef50_Q2SC27 Cluster: Deacetylases, including yeast histone d... 56 1e-06
UniRef50_Q1N4R7 Cluster: Deacetylases, including yeast histone d... 56 1e-06
UniRef50_A6VSZ5 Cluster: Histone deacetylase superfamily; n=4; G... 56 1e-06
UniRef50_A6Q2Z0 Cluster: Acetoin utilization protein; n=1; Nitra... 56 1e-06
UniRef50_A6G5J4 Cluster: Histone deacetylase superfamily protein... 56 1e-06
UniRef50_A5GUP9 Cluster: Histone deacetylase family protein; n=1... 56 1e-06
UniRef50_Q00UC4 Cluster: Histone deacetylase superfamily; n=2; O... 56 1e-06
UniRef50_A7SSG8 Cluster: Predicted protein; n=2; Eumetazoa|Rep: ... 56 1e-06
UniRef50_A0B6D0 Cluster: Histone deacetylase superfamily; n=1; M... 56 1e-06
UniRef50_Q586J9 Cluster: Histone deacetylase, putative; n=1; Try... 42 2e-06
UniRef50_Q0G2C9 Cluster: Putative acetylpolyamine aminohydrolase... 55 2e-06
UniRef50_Q8TWH9 Cluster: Predicted deacetylase; n=1; Methanopyru... 55 2e-06
UniRef50_Q4TFH7 Cluster: Chromosome undetermined SCAF4471, whole... 54 3e-06
UniRef50_Q4T0M8 Cluster: Chromosome undetermined SCAF10929, whol... 54 3e-06
UniRef50_Q31EP6 Cluster: Histone deacetylase family protein prec... 54 3e-06
UniRef50_A7HL59 Cluster: Histone deacetylase superfamily; n=1; F... 54 3e-06
UniRef50_A6T202 Cluster: Histone deacetylase superfamily protein... 54 3e-06
UniRef50_Q944K3 Cluster: Histone deacetylase 2; n=7; Magnoliophy... 54 3e-06
UniRef50_Q8LRK8 Cluster: Histone deacetylase 18; n=1; Arabidopsi... 54 3e-06
UniRef50_Q969S8 Cluster: Histone deacetylase 10; n=20; Euteleost... 54 3e-06
UniRef50_A0G5H0 Cluster: Histone deacetylase superfamily; n=9; P... 54 4e-06
UniRef50_Q8WUI4 Cluster: Histone deacetylase 7a; n=41; Tetrapoda... 54 4e-06
UniRef50_Q20296 Cluster: Histone deacetylase 6; n=4; Caenorhabdi... 54 4e-06
UniRef50_Q4RSK1 Cluster: Chromosome 13 SCAF15000, whole genome s... 54 5e-06
UniRef50_Q604Q2 Cluster: Histone deacetylase/AcuC/AphA family pr... 54 5e-06
UniRef50_Q9VC26 Cluster: CG31119-PA; n=5; Diptera|Rep: CG31119-P... 54 5e-06
UniRef50_Q569C4 Cluster: Histone deacetylase 10; n=5; Mammalia|R... 54 5e-06
UniRef50_O67877 Cluster: Acetoin utilization protein; n=3; Bacte... 53 7e-06
UniRef50_A6GQW9 Cluster: Histone deacetylase family protein; n=1... 53 7e-06
UniRef50_Q9UQL6 Cluster: Histone deacetylase 5; n=141; Eumetazoa... 53 7e-06
UniRef50_Q8EFZ9 Cluster: Histone deacetylase/AcuC/AphA family pr... 53 9e-06
UniRef50_A6C2D6 Cluster: Deacetylase; n=1; Planctomyces maris DS... 53 9e-06
UniRef50_A5UY48 Cluster: Histone deacetylase superfamily; n=4; C... 53 9e-06
UniRef50_Q8WZR5 Cluster: Related to histone deacetylase A; n=4; ... 53 9e-06
UniRef50_UPI000065F55A Cluster: Histone deacetylase 7a (HD7a).; ... 52 1e-05
UniRef50_A1G0Y5 Cluster: Histone deacetylase superfamily precurs... 52 1e-05
UniRef50_O17323 Cluster: Histone deacetylase 4; n=3; Caenorhabdi... 52 1e-05
UniRef50_UPI0000E87DA7 Cluster: histone deacetylase family prote... 52 2e-05
UniRef50_Q0YKV4 Cluster: Histone deacetylase superfamily; n=1; G... 52 2e-05
UniRef50_A4C9H1 Cluster: Putative histone deacetylase family pro... 52 2e-05
UniRef50_UPI000051A1DA Cluster: PREDICTED: similar to HDAC4 CG17... 52 2e-05
UniRef50_A1ID65 Cluster: Histone deacetylase family protein; n=1... 52 2e-05
UniRef50_A0LGT0 Cluster: Histone deacetylase superfamily; n=1; S... 52 2e-05
UniRef50_Q6KAT4 Cluster: MFLJ00062 protein; n=6; Eutheria|Rep: M... 51 3e-05
UniRef50_A0KLZ2 Cluster: Histone deacetylase/AcuC/AphA family pr... 51 3e-05
UniRef50_Q4CZ55 Cluster: Histone deacetylase, putative; n=2; Try... 51 3e-05
UniRef50_O27262 Cluster: Uncharacterized protein MTH_1194; n=1; ... 51 3e-05
UniRef50_UPI0000D561E8 Cluster: PREDICTED: similar to CG1770-PA,... 51 4e-05
UniRef50_A2AWS5 Cluster: Histone deacetylase 5; n=21; Euarchonto... 51 4e-05
UniRef50_Q1AYS6 Cluster: Histone deacetylase superfamily; n=1; R... 51 4e-05
UniRef50_A6VZD7 Cluster: Histone deacetylase superfamily; n=2; M... 51 4e-05
UniRef50_A3ZYN7 Cluster: Acetoin utilization protein; n=3; Planc... 50 5e-05
UniRef50_A1I9M7 Cluster: Histone deacetylase superfamily; n=1; C... 50 5e-05
UniRef50_Q5VP96 Cluster: HGWP repeat containing protein-like; n=... 50 5e-05
UniRef50_Q9U266 Cluster: Putative uncharacterized protein hda-6;... 50 5e-05
UniRef50_Q5KNI3 Cluster: Histone deacetylase, putative; n=2; Fil... 50 5e-05
UniRef50_O27994 Cluster: Acetylpolyamine aminohydrolase, putativ... 50 5e-05
UniRef50_UPI00005A01A4 Cluster: PREDICTED: similar to histone de... 50 6e-05
UniRef50_UPI000065FABE Cluster: Histone deacetylase 6 (HD6).; n=... 50 6e-05
UniRef50_Q1NWE2 Cluster: Histone deacetylase superfamily; n=2; d... 50 6e-05
UniRef50_Q8I9J6 Cluster: Histone deacetylase dHDAC4 isoform b; n... 50 6e-05
UniRef50_Q1DTF8 Cluster: Putative uncharacterized protein; n=1; ... 50 6e-05
UniRef50_A3VQ74 Cluster: Probable histone deacetylase/AcuC/AphA ... 49 1e-04
UniRef50_Q2FQ17 Cluster: Histone deacetylase superfamily; n=1; M... 49 1e-04
UniRef50_P56523 Cluster: Histone deacetylase clr3; n=1; Schizosa... 49 1e-04
UniRef50_Q3IF01 Cluster: Putative histone deacetylase family pro... 49 1e-04
UniRef50_Q1VK67 Cluster: Histone deacetylase family protein; n=1... 49 1e-04
UniRef50_A6LM84 Cluster: Histone deacetylase superfamily; n=1; T... 49 1e-04
UniRef50_Q70I53 Cluster: Histone deacetylase-like amidohydrolase... 49 1e-04
UniRef50_Q96DB2 Cluster: Histone deacetylase 11; n=22; Eumetazoa... 49 1e-04
UniRef50_Q9HSP7 Cluster: Acetoin utilization protein; n=5; Halob... 48 2e-04
UniRef50_Q9RW36 Cluster: Histone deacetylase/AcuC/AphA family pr... 48 3e-04
UniRef50_A5VD94 Cluster: Histone deacetylase superfamily; n=6; A... 48 3e-04
UniRef50_UPI0000F2108C Cluster: PREDICTED: hypothetical protein;... 48 3e-04
UniRef50_Q30PJ4 Cluster: Histone deacetylase superfamily; n=1; T... 48 3e-04
UniRef50_Q128P1 Cluster: Histone deacetylase superfamily; n=16; ... 48 3e-04
UniRef50_A4AX75 Cluster: Histone deacetylase/AcuC/AphA family pr... 48 3e-04
UniRef50_A0LFA3 Cluster: Histone deacetylase superfamily; n=3; D... 48 3e-04
UniRef50_A0C8R8 Cluster: Chromosome undetermined scaffold_159, w... 48 3e-04
UniRef50_Q8U2L6 Cluster: Aminohydrolase; n=4; Thermococcaceae|Re... 48 3e-04
UniRef50_Q987Q0 Cluster: Acetylpolyamine aminohydrolase; n=1; Me... 47 5e-04
UniRef50_Q985Y7 Cluster: Mlr7469 protein; n=13; Alphaproteobacte... 47 5e-04
UniRef50_A5WHG1 Cluster: Histone deacetylase superfamily; n=17; ... 47 5e-04
UniRef50_A5UTM3 Cluster: Histone deacetylase superfamily; n=4; B... 47 5e-04
UniRef50_Q7S8C9 Cluster: Putative uncharacterized protein NCU070... 47 5e-04
UniRef50_O28982 Cluster: Acetoin utilization protein, putative; ... 47 5e-04
UniRef50_UPI000023CBFE Cluster: hypothetical protein FG05636.1; ... 47 6e-04
UniRef50_A6EYD2 Cluster: Histone deacetylase superfamily protein... 47 6e-04
UniRef50_Q2H2N4 Cluster: Putative uncharacterized protein; n=1; ... 46 8e-04
UniRef50_Q2IF50 Cluster: Histone deacetylase superfamily; n=1; A... 46 0.001
UniRef50_UPI0000F1E289 Cluster: PREDICTED: hypothetical protein;... 46 0.001
UniRef50_A4QWC2 Cluster: Putative uncharacterized protein; n=1; ... 46 0.001
UniRef50_Q9YG09 Cluster: Putative uncharacterized protein; n=1; ... 46 0.001
UniRef50_Q6AJC0 Cluster: Putative uncharacterized protein; n=1; ... 45 0.002
UniRef50_Q4W9N7 Cluster: Histone deacetylase HosB; n=3; Trichoco... 45 0.002
UniRef50_Q57955 Cluster: Uncharacterized protein MJ0535; n=1; Me... 45 0.002
UniRef50_Q0AUZ2 Cluster: Deacetylase family protrein; n=2; Clost... 45 0.002
UniRef50_Q2QWU2 Cluster: Histone deacetylase family protein, exp... 45 0.002
UniRef50_A4BSQ6 Cluster: Histone deacetylase/AcuC/AphA family pr... 44 0.003
UniRef50_A2WM81 Cluster: Putative uncharacterized protein; n=1; ... 44 0.003
UniRef50_Q0M412 Cluster: Histone deacetylase superfamily; n=1; C... 44 0.004
UniRef50_A3K7Q8 Cluster: Acetylpolyamine aminohydrolase; n=1; Sa... 44 0.004
UniRef50_A4S240 Cluster: Predicted protein; n=2; Ostreococcus|Re... 44 0.004
UniRef50_Q1DM14 Cluster: Putative uncharacterized protein; n=1; ... 44 0.004
UniRef50_Q12A19 Cluster: Histone deacetylase superfamily; n=4; P... 44 0.006
UniRef50_Q5C2D1 Cluster: SJCHGC03352 protein; n=1; Schistosoma j... 44 0.006
UniRef50_Q4P2D6 Cluster: Putative uncharacterized protein; n=1; ... 44 0.006
UniRef50_A2R2F5 Cluster: Remark: N-terminal truncated orf due to... 44 0.006
UniRef50_A3H8X1 Cluster: Histone deacetylase superfamily; n=1; C... 44 0.006
UniRef50_Q48935 Cluster: Acetylpolyamine aminohydrolase; n=32; P... 44 0.006
UniRef50_Q8F7M9 Cluster: Histone deacetylase family protein; n=4... 43 0.007
UniRef50_A0Z891 Cluster: Deacetylases, including yeast histone d... 43 0.007
UniRef50_Q8IJW3 Cluster: Putative uncharacterized protein; n=3; ... 43 0.007
UniRef50_Q7R8P2 Cluster: Histone deacetylase family, putative; n... 43 0.007
UniRef50_Q4YUE6 Cluster: Putative uncharacterized protein; n=3; ... 43 0.007
UniRef50_Q4UB07 Cluster: Histone deacetylase family protein, put... 43 0.007
UniRef50_A3J841 Cluster: Histone deacetylase family protein; n=2... 43 0.010
UniRef50_A5K7A1 Cluster: Putative uncharacterized protein; n=1; ... 43 0.010
UniRef50_A6RSL3 Cluster: Putative uncharacterized protein; n=2; ... 43 0.010
UniRef50_A5UZV6 Cluster: Histone deacetylase superfamily; n=5; B... 42 0.013
UniRef50_Q54VQ7 Cluster: Putative uncharacterized protein; n=2; ... 42 0.013
UniRef50_Q194I2 Cluster: Histone deacetylase superfamily; n=2; D... 42 0.017
UniRef50_Q7Z8L8 Cluster: Putative HOS3-like histone deacetylase;... 42 0.017
UniRef50_A3EUN7 Cluster: Histone deacetylase family protein; n=1... 42 0.023
UniRef50_Q941D6 Cluster: Histone deacetylase 14; n=3; Spermatoph... 42 0.023
UniRef50_A5AUM3 Cluster: Putative uncharacterized protein; n=2; ... 41 0.040
UniRef50_A0DIS2 Cluster: Chromosome undetermined scaffold_52, wh... 41 0.040
UniRef50_Q8TLY4 Cluster: Histone deacetylase; n=3; cellular orga... 41 0.040
UniRef50_A1U7D4 Cluster: Histone deacetylase superfamily; n=5; P... 40 0.052
UniRef50_A3DNS7 Cluster: Histone deacetylase superfamily; n=1; S... 40 0.052
UniRef50_A2BL29 Cluster: Predicted Histone deacetylase; n=1; Hyp... 40 0.052
UniRef50_P72702 Cluster: Uncharacterized protein slr0245; n=15; ... 40 0.052
UniRef50_A1ZSA9 Cluster: Histone deacetylase family protein, put... 40 0.092
UniRef50_Q10IB7 Cluster: Putative uncharacterized protein; n=1; ... 40 0.092
UniRef50_A5K337 Cluster: Histone deactylase, putative; n=4; Plas... 40 0.092
UniRef50_Q8GXJ1 Cluster: Histone deacetylase 15; n=11; Magnoliop... 40 0.092
UniRef50_Q5AF34 Cluster: Likely histone deacetylase Hos3p; n=5; ... 39 0.12
UniRef50_Q4WE71 Cluster: Histone deacetylase HdaA; n=1; Aspergil... 39 0.16
UniRef50_A5E451 Cluster: Putative uncharacterized protein; n=1; ... 39 0.16
UniRef50_Q8IKB6 Cluster: Histone deacetylase, putative; n=4; Alv... 38 0.21
UniRef50_Q54X15 Cluster: Putative uncharacterized protein; n=1; ... 38 0.21
UniRef50_Q4QI60 Cluster: Histone deacetylase, putative; n=3; Lei... 38 0.21
UniRef50_Q981D8 Cluster: Deacetylase, putative; n=3; Sulfolobus|... 38 0.21
UniRef50_A4S2N1 Cluster: Predicted protein; n=2; Ostreococcus|Re... 38 0.28
UniRef50_Q6CGA7 Cluster: Similar to sp|Q02959 Saccharomyces cere... 38 0.28
UniRef50_Q74MV2 Cluster: NEQ538; n=1; Nanoarchaeum equitans|Rep:... 38 0.37
UniRef50_A3W9J6 Cluster: Histone deacetylase superfamily protein... 37 0.49
UniRef50_Q8RAS9 Cluster: Deacetylases, including yeast histone d... 36 1.5
UniRef50_A2R705 Cluster: Contig An16c0070, complete genome; n=2;... 36 1.5
UniRef50_Q02959 Cluster: Histone deacetylase HOS3; n=6; Saccharo... 36 1.5
UniRef50_Q012I9 Cluster: FOG: Ankyrin repeat; n=3; Ostreococcus|... 35 2.0
UniRef50_Q4UBL2 Cluster: Histone deacetylase family protein, put... 35 2.0
UniRef50_P16466 Cluster: Hemolysin precursor; n=1; Proteus mirab... 35 2.0
UniRef50_Q232Y2 Cluster: Histone deacetylase family protein; n=1... 35 2.6
UniRef50_Q1MQQ3 Cluster: Deacetylases, including yeast histone d... 34 3.4
UniRef50_Q8ZU23 Cluster: Acetylpolyamine aminohydrolase, putativ... 34 3.4
UniRef50_Q1ZJU4 Cluster: Putative uncharacterized protein; n=6; ... 34 4.6
UniRef50_A0CGA0 Cluster: Chromosome undetermined scaffold_179, w... 33 6.0
UniRef50_Q3SA60 Cluster: Deacetylase; n=1; uncultured euryarchae... 33 6.0
UniRef50_UPI0000E477A9 Cluster: PREDICTED: similar to class 4 HD... 33 8.0
UniRef50_Q6EQZ2 Cluster: Putative uncharacterized protein OSJNBa... 33 8.0
UniRef50_Q4QBZ5 Cluster: Histone deacetylase, putative; n=3; Lei... 33 8.0
>UniRef50_UPI000065D235 Cluster: Histone deacetylase 1 (HD1).; n=1;
Takifugu rubripes|Rep: Histone deacetylase 1 (HD1). -
Takifugu rubripes
Length = 460
Score = 348 bits (856), Expect = 8e-95
Identities = 156/195 (80%), Positives = 171/195 (87%)
Frame = +1
Query: 193 MSMQPHSKKRVCXXXXXXXXXXXXXQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKAT 372
M++ +KK+VC QGHPMKPHRIRMTHNLLLNYGLYR+MEIYRPHKA+
Sbjct: 1 MALSQGTKKKVCYYYDGDVGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRRMEIYRPHKAS 60
Query: 373 ADEMTKFHSDDYIRFLRSIRPDNVSEYNKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAA 552
+EMTK+HSDDYI+FLRSIRPDN+SEY+KQMQRFNVGEDCPVFDGL+EFCQLS GGSVA
Sbjct: 61 GEEMTKYHSDDYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVAG 120
Query: 553 AVKLNKQASEICINWGGGLHHAKKSEASGFCYVNDIVLGILELLKYHQRVLYIDIDVHHG 732
AVKLNKQ ++I INW GGLHHAKKSEASGFCYVNDIVL ILELLKYHQRVLYIDID+HHG
Sbjct: 121 AVKLNKQQTDIAINWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHG 180
Query: 733 DGVEXAFYTTDRVMT 777
DGVE AFYTTDRVMT
Sbjct: 181 DGVEEAFYTTDRVMT 195
>UniRef50_Q13547 Cluster: Histone deacetylase 1; n=60; Fungi/Metazoa
group|Rep: Histone deacetylase 1 - Homo sapiens (Human)
Length = 482
Score = 347 bits (853), Expect = 2e-94
Identities = 155/195 (79%), Positives = 171/195 (87%)
Frame = +1
Query: 193 MSMQPHSKKRVCXXXXXXXXXXXXXQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKAT 372
M+ ++++VC QGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKA
Sbjct: 1 MAQTQGTRRKVCYYYDGDVGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKAN 60
Query: 373 ADEMTKFHSDDYIRFLRSIRPDNVSEYNKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAA 552
A+EMTK+HSDDYI+FLRSIRPDN+SEY+KQMQRFNVGEDCPVFDGL+EFCQLS GGSVA+
Sbjct: 61 AEEMTKYHSDDYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVAS 120
Query: 553 AVKLNKQASEICINWGGGLHHAKKSEASGFCYVNDIVLGILELLKYHQRVLYIDIDVHHG 732
AVKLNKQ ++I +NW GGLHHAKKSEASGFCYVNDIVL ILELLKYHQRVLYIDID+HHG
Sbjct: 121 AVKLNKQQTDIAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHG 180
Query: 733 DGVEXAFYTTDRVMT 777
DGVE AFYTTDRVMT
Sbjct: 181 DGVEEAFYTTDRVMT 195
>UniRef50_Q92769 Cluster: Histone deacetylase 2; n=50;
Eukaryota|Rep: Histone deacetylase 2 - Homo sapiens
(Human)
Length = 488
Score = 346 bits (851), Expect = 3e-94
Identities = 155/192 (80%), Positives = 169/192 (88%)
Frame = +1
Query: 202 QPHSKKRVCXXXXXXXXXXXXXQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADE 381
Q KK+VC QGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATA+E
Sbjct: 5 QGGGKKKVCYYYDGDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATAEE 64
Query: 382 MTKFHSDDYIRFLRSIRPDNVSEYNKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAAVK 561
MTK+HSD+YI+FLRSIRPDN+SEY+KQMQRFNVGEDCPVFDGL+EFCQLS GGSVA AVK
Sbjct: 65 MTKYHSDEYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVAGAVK 124
Query: 562 LNKQASEICINWGGGLHHAKKSEASGFCYVNDIVLGILELLKYHQRVLYIDIDVHHGDGV 741
LN+Q +++ +NW GGLHHAKKSEASGFCYVNDIVL ILELLKYHQRVLYIDID+HHGDGV
Sbjct: 125 LNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGV 184
Query: 742 EXAFYTTDRVMT 777
E AFYTTDRVMT
Sbjct: 185 EEAFYTTDRVMT 196
>UniRef50_Q9HDT2 Cluster: Histone deacetylase; n=4; Fungi/Metazoa
group|Rep: Histone deacetylase - Ustilago maydis (Smut
fungus)
Length = 566
Score = 268 bits (657), Expect = 1e-70
Identities = 115/167 (68%), Positives = 138/167 (82%)
Frame = +1
Query: 277 PMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVSEYN 456
PMKPHR+RMTHNL+ NYGL++KM+I RP +AT D+MT+FH+D+Y+ FL + P+ V E
Sbjct: 13 PMKPHRMRMTHNLVTNYGLHKKMDILRPKRATRDQMTRFHTDEYVDFLHRVTPETVHELT 72
Query: 457 KQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAAVKLNKQASEICINWGGGLHHAKKSEAS 636
+ R+ +GEDCP FDGLYEFC +SAGGS+AAA +LN S++ INW GGLHHAKK EAS
Sbjct: 73 NEGTRYLIGEDCPAFDGLYEFCSISAGGSLAAATRLNSGESDVAINWAGGLHHAKKREAS 132
Query: 637 GFCYVNDIVLGILELLKYHQRVLYIDIDVHHGDGVEXAFYTTDRVMT 777
GFCYVNDIVL ILELL+ H RVLYIDID+HHGDGVE AFYTTDRVMT
Sbjct: 133 GFCYVNDIVLAILELLRVHLRVLYIDIDIHHGDGVEEAFYTTDRVMT 179
>UniRef50_A3BWV6 Cluster: Putative uncharacterized protein; n=2;
Oryza sativa|Rep: Putative uncharacterized protein -
Oryza sativa subsp. japonica (Rice)
Length = 384
Score = 258 bits (633), Expect = 8e-68
Identities = 113/170 (66%), Positives = 141/170 (82%)
Frame = +1
Query: 268 QGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVS 447
QGHPMKPHRIRM H+L+++YGL+R +E+ RP+ A+ ++ +FHSDDY+ FL S +
Sbjct: 39 QGHPMKPHRIRMAHSLVVHYGLHRLLELSRPYPASDADIRRFHSDDYVAFLASATGNPAL 98
Query: 448 EYNKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAAVKLNKQASEICINWGGGLHHAKKS 627
+ ++RFNVGEDCPVFDGL+ FCQ SAGGS+ AAVKLN+ ++I +NW GGLHHAKK
Sbjct: 99 LDARAVKRFNVGEDCPVFDGLFPFCQASAGGSIGAAVKLNRGDADITVNWAGGLHHAKKG 158
Query: 628 EASGFCYVNDIVLGILELLKYHQRVLYIDIDVHHGDGVEXAFYTTDRVMT 777
EASGFCYVNDIVL ILELLK+H+RVLY+DIDVHHGDGVE AF+TT+RVMT
Sbjct: 159 EASGFCYVNDIVLAILELLKFHRRVLYVDIDVHHGDGVEEAFFTTNRVMT 208
>UniRef50_O15379 Cluster: Histone deacetylase 3; n=149;
Eukaryota|Rep: Histone deacetylase 3 - Homo sapiens
(Human)
Length = 428
Score = 256 bits (627), Expect = 4e-67
Identities = 107/169 (63%), Positives = 136/169 (80%)
Frame = +1
Query: 271 GHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVSE 450
GHPMKPHR+ +TH+L+L+YGLY+KM +++P++A+ +M +FHS+DYI FL+ + P N+
Sbjct: 21 GHPMKPHRLALTHSLVLHYGLYKKMIVFKPYQASQHDMCRFHSEDYIDFLQRVSPTNMQG 80
Query: 451 YNKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAAVKLNKQASEICINWGGGLHHAKKSE 630
+ K + FNVG+DCPVF GL+EFC G S+ A +LN + +I INW GGLHHAKK E
Sbjct: 81 FTKSLNAFNVGDDCPVFPGLFEFCSRYTGASLQGATQLNNKICDIAINWAGGLHHAKKFE 140
Query: 631 ASGFCYVNDIVLGILELLKYHQRVLYIDIDVHHGDGVEXAFYTTDRVMT 777
ASGFCYVNDIV+GILELLKYH RVLYIDID+HHGDGV+ AFY TDRVMT
Sbjct: 141 ASGFCYVNDIVIGILELLKYHPRVLYIDIDIHHGDGVQEAFYLTDRVMT 189
>UniRef50_A2FDZ0 Cluster: Acetylpolyamine aminohydrolase, putative;
n=1; Trichomonas vaginalis G3|Rep: Acetylpolyamine
aminohydrolase, putative - Trichomonas vaginalis G3
Length = 453
Score = 239 bits (586), Expect = 4e-62
Identities = 98/188 (52%), Positives = 137/188 (72%)
Frame = +1
Query: 214 KKRVCXXXXXXXXXXXXXQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKF 393
K+R+ HPMKP R+RMTH+L+L Y L+ M+++ P +A+ +EM +F
Sbjct: 5 KRRIAYFYDEDIGNYYYTHSHPMKPVRVRMTHSLVLGYKLHEHMDVFHPRRASPEEMMRF 64
Query: 394 HSDDYIRFLRSIRPDNVSEYNKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAAVKLNKQ 573
H+ YI+FL++ P N + ++ +N+G DCPVFD ++EFCQ+SAGGS++AA +LN
Sbjct: 65 HTPGYIKFLQTATPSNTNPKSEDAVHYNIGFDCPVFDNIFEFCQISAGGSISAAQRLNYN 124
Query: 574 ASEICINWGGGLHHAKKSEASGFCYVNDIVLGILELLKYHQRVLYIDIDVHHGDGVEXAF 753
+++ INW GGLHHA++ +ASGFCY+ D VLGI+ELLKYH RV+YIDID+HHGDGVE AF
Sbjct: 125 LADVAINWAGGLHHARRDQASGFCYIADCVLGIMELLKYHPRVMYIDIDIHHGDGVEEAF 184
Query: 754 YTTDRVMT 777
Y TDRV+T
Sbjct: 185 YNTDRVLT 192
>UniRef50_Q5KKR8 Cluster: Histone deacetylase 1-1 (Hd1), putative;
n=3; Filobasidiella neoformans|Rep: Histone deacetylase
1-1 (Hd1), putative - Cryptococcus neoformans
(Filobasidiella neoformans)
Length = 659
Score = 209 bits (510), Expect(2) = 2e-61
Identities = 91/147 (61%), Positives = 114/147 (77%)
Frame = +1
Query: 337 RKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVSEYNKQMQRFNVGEDCPVFDGLYE 516
++M+I+RP +AT +MT+FH+D+YI L S+ P+N R G DCP +G++E
Sbjct: 97 KRMQIFRPRRATKTDMTRFHTDEYIELLESVLPENADALTGNRSRGLTGSDCPAVEGIFE 156
Query: 517 FCQLSAGGSVAAAVKLNKQASEICINWGGGLHHAKKSEASGFCYVNDIVLGILELLKYHQ 696
F +SAGGS+ AA KLN+ ++I INW GGLHHAKK+EASGFCYVNDIVLGILELL+ +
Sbjct: 157 FSSISAGGSIGAAEKLNEGIADIAINWAGGLHHAKKTEASGFCYVNDIVLGILELLRVNS 216
Query: 697 RVLYIDIDVHHGDGVEXAFYTTDRVMT 777
RVLYIDIDVHHGDGVE AFY+TDRVMT
Sbjct: 217 RVLYIDIDVHHGDGVEEAFYSTDRVMT 243
Score = 50.0 bits (114), Expect(2) = 2e-61
Identities = 22/29 (75%), Positives = 24/29 (82%), Gaps = 3/29 (10%)
Frame = +1
Query: 271 GHPMKPHRIRMTHNLLLNYGL---YRKME 348
GHPMKPHRIRMTHNL++NYGL Y ME
Sbjct: 38 GHPMKPHRIRMTHNLVVNYGLADDYEAME 66
>UniRef50_Q4WHY0 Cluster: Histone deacetylase HosA; n=15;
Fungi/Metazoa group|Rep: Histone deacetylase HosA -
Aspergillus fumigatus (Sartorya fumigata)
Length = 487
Score = 233 bits (570), Expect = 4e-60
Identities = 101/172 (58%), Positives = 132/172 (76%), Gaps = 2/172 (1%)
Frame = +1
Query: 268 QGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVS 447
Q HPMKP R+ +T L++ YG++ M++Y AT +EM +FH DY+ FLR + P ++
Sbjct: 58 QSHPMKPWRLTLTKQLVMAYGMHHAMDLYLARAATYEEMAEFHQTDYLDFLRQVMPGDME 117
Query: 448 --EYNKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAAVKLNKQASEICINWGGGLHHAK 621
E ++ + RFN G+DCP+F+GLY +C L AGGS+ AA KL SEI +NW GGLHHAK
Sbjct: 118 NPEQSENIARFNFGDDCPIFNGLYNYCSLYAGGSIDAARKLCNNQSEIAVNWSGGLHHAK 177
Query: 622 KSEASGFCYVNDIVLGILELLKYHQRVLYIDIDVHHGDGVEXAFYTTDRVMT 777
K+EASGFCYVNDIVLGIL+LL++H RV+YIDIDVHHGDGVE AF++TDRV+T
Sbjct: 178 KAEASGFCYVNDIVLGILQLLRHHPRVMYIDIDVHHGDGVEQAFWSTDRVLT 229
>UniRef50_Q5U8M9 Cluster: Histone deacetylase 1; n=2; Entamoeba
histolytica|Rep: Histone deacetylase 1 - Entamoeba
histolytica
Length = 448
Score = 230 bits (562), Expect = 3e-59
Identities = 100/188 (53%), Positives = 134/188 (71%), Gaps = 2/188 (1%)
Frame = +1
Query: 220 RVCXXXXXXXXXXXXXQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHS 399
RVC GHPMKP R ++ H+L++ YG+Y+++ IY+P +AT ++M FHS
Sbjct: 3 RVCYFYDQNVGEFDYGFGHPMKPLRNKLVHHLIMEYGIYKRLNIYKPWRATNEQMEMFHS 62
Query: 400 DDYIRFLRSIRPDNVSE--YNKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAAVKLNKQ 573
+YI FL+ + P+ + + K ++ FN +DCPVF+GLY F Q G S+ A+K+N++
Sbjct: 63 KEYIDFLQRVTPEMALQPHFKKSLEEFNFTDDCPVFEGLYPFVQTVVGSSLGCAMKINER 122
Query: 574 ASEICINWGGGLHHAKKSEASGFCYVNDIVLGILELLKYHQRVLYIDIDVHHGDGVEXAF 753
A++IC+NW GGLHHAKKS+ASGFCY+NDIV ILELLK H RVLYIDID HHGDGVE AF
Sbjct: 123 AADICVNWSGGLHHAKKSQASGFCYINDIVCAILELLKVHSRVLYIDIDHHHGDGVEEAF 182
Query: 754 YTTDRVMT 777
T+RVMT
Sbjct: 183 KATNRVMT 190
>UniRef50_Q5XTS3 Cluster: Histone deacetylase HDAC; n=2; Giardia
intestinalis|Rep: Histone deacetylase HDAC - Giardia
lamblia (Giardia intestinalis)
Length = 467
Score = 221 bits (541), Expect = 1e-56
Identities = 94/168 (55%), Positives = 123/168 (73%)
Frame = +1
Query: 274 HPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVSEY 453
HPMKP RI + + L+L YGL + Y P AT +M +H+ DYIRFL++I P+ +S++
Sbjct: 23 HPMKPFRIALVNELILAYGLDEHLNYYTPRDATFQDMALYHTPDYIRFLKNITPETLSKF 82
Query: 454 NKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAAVKLNKQASEICINWGGGLHHAKKSEA 633
+R+N+ EDCPVF GLY++C ++ G SV A LN ++ +NW GG HHAK SEA
Sbjct: 83 QDLAKRYNITEDCPVFSGLYDYCSMTVGASVNACAHLNHGMCDVALNWMGGFHHAKASEA 142
Query: 634 SGFCYVNDIVLGILELLKYHQRVLYIDIDVHHGDGVEXAFYTTDRVMT 777
SGFCY ND+VLGILELLK H+RVLY+DID+H GDGVE AFYTT+RV+T
Sbjct: 143 SGFCYANDLVLGILELLKVHERVLYVDIDIHAGDGVEEAFYTTNRVLT 190
>UniRef50_P53096 Cluster: Probable histone deacetylase HOS2; n=15;
Dikarya|Rep: Probable histone deacetylase HOS2 -
Saccharomyces cerevisiae (Baker's yeast)
Length = 452
Score = 220 bits (537), Expect = 4e-56
Identities = 93/169 (55%), Positives = 125/169 (73%), Gaps = 1/169 (0%)
Frame = +1
Query: 274 HPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVSEY 453
HPMKP R+ +T +L+ +YGL++ M++Y AT DE+ +FHS+DY+ FL + P+N ++
Sbjct: 45 HPMKPFRLMLTDHLVSSYGLHKIMDLYETRSATRDELLQFHSEDYVNFLSKVSPENANKL 104
Query: 454 NK-QMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAAVKLNKQASEICINWGGGLHHAKKSE 630
+ ++ FN+G+DCP+F LY++ L G S+ A KL S+I INW GGLHHAKK+
Sbjct: 105 PRGTLENFNIGDDCPIFQNLYDYTTLYTGASLDATRKLINNQSDIAINWSGGLHHAKKNS 164
Query: 631 ASGFCYVNDIVLGILELLKYHQRVLYIDIDVHHGDGVEXAFYTTDRVMT 777
SGFCYVNDIVL IL LL+YH R+LYIDID+HHGDGV+ AFYTTDRV T
Sbjct: 165 PSGFCYVNDIVLSILNLLRYHPRILYIDIDLHHGDGVQEAFYTTDRVFT 213
>UniRef50_Q09440 Cluster: Putative histone deacetylase 2; n=2;
Caenorhabditis|Rep: Putative histone deacetylase 2 -
Caenorhabditis elegans
Length = 507
Score = 215 bits (526), Expect = 8e-55
Identities = 95/171 (55%), Positives = 133/171 (77%), Gaps = 1/171 (0%)
Frame = +1
Query: 268 QGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPD-NV 444
Q HPMKP R+ + ++L+++Y + + M + K A +++ FH++DY+ FL+++ P +
Sbjct: 46 QLHPMKPQRLVVCNDLVVSYEMPKYMTVVESPKLDAADISVFHTEDYVNFLQTVTPKLGL 105
Query: 445 SEYNKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAAVKLNKQASEICINWGGGLHHAKK 624
+ + +++FN+GEDCP+F GL+++C L AGGSV A +LN + ++I INW GGLHHAKK
Sbjct: 106 TMPDDVLRQFNIGEDCPIFAGLWDYCTLYAGGSVEGARRLNHKMNDIVINWPGGLHHAKK 165
Query: 625 SEASGFCYVNDIVLGILELLKYHQRVLYIDIDVHHGDGVEXAFYTTDRVMT 777
SEASGFCYVNDIVLGILELLKYH+RVLYIDID+HHGDGV+ AF +DRVMT
Sbjct: 166 SEASGFCYVNDIVLGILELLKYHKRVLYIDIDIHHGDGVQEAFNNSDRVMT 216
>UniRef50_A4RK28 Cluster: Putative uncharacterized protein; n=1;
Magnaporthe grisea|Rep: Putative uncharacterized protein
- Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 466
Score = 211 bits (516), Expect = 1e-53
Identities = 98/174 (56%), Positives = 128/174 (73%), Gaps = 4/174 (2%)
Frame = +1
Query: 268 QGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVS 447
Q HPMKP R+ ++ L+ +YG+ M+ Y AT DE+T FH+ DYI+FL ++ P+ +
Sbjct: 81 QTHPMKPWRLTLSKALISSYGMNFAMDNYVSRAATYDELTMFHASDYIQFLGTVLPEPIP 140
Query: 448 EYNKQMQ---RFNVG-EDCPVFDGLYEFCQLSAGGSVAAAVKLNKQASEICINWGGGLHH 615
+FN+G DCP+F+GLY++C +SAGGS+ AA K+ S+I I WGGGLHH
Sbjct: 141 RDVDNPYPDLKFNLGGSDCPLFEGLYDYCSMSAGGSLDAARKICNNQSDIAIAWGGGLHH 200
Query: 616 AKKSEASGFCYVNDIVLGILELLKYHQRVLYIDIDVHHGDGVEXAFYTTDRVMT 777
AK+SEASGFCY+NDIV+ IL+LL+ H RVLYIDIDVHHGDGVE AFY+TDRVMT
Sbjct: 201 AKRSEASGFCYINDIVIAILQLLRCHPRVLYIDIDVHHGDGVEEAFYSTDRVMT 254
>UniRef50_A0DPM0 Cluster: Chromosome undetermined scaffold_59, whole
genome shotgun sequence; n=7; Eukaryota|Rep: Chromosome
undetermined scaffold_59, whole genome shotgun sequence
- Paramecium tetraurelia
Length = 443
Score = 205 bits (500), Expect = 1e-51
Identities = 98/175 (56%), Positives = 120/175 (68%), Gaps = 7/175 (4%)
Frame = +1
Query: 274 HPMKPHRIRMTHNLLLNYGLYRKMEIYRPH-------KATADEMTKFHSDDYIRFLRSIR 432
HPMKP R+ +T +L+ +YGL + M + D +T+FHS +YI ++ I
Sbjct: 44 HPMKPLRVAITDDLVGHYGLKQYMNCIDQSFVQTYIKRVDEDVLTQFHSYEYIDLIKIIT 103
Query: 433 PDNVSEYNKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAAVKLNKQASEICINWGGGLH 612
P+N +Y Q+ RFN EDCPV D L++FC GSV AA + Q S I INW GGLH
Sbjct: 104 PENKCQYEDQLYRFNFMEDCPVLDRLFDFCLCQTSGSVGAACVIADQKSNIAINWSGGLH 163
Query: 613 HAKKSEASGFCYVNDIVLGILELLKYHQRVLYIDIDVHHGDGVEXAFYTTDRVMT 777
HAK+SEASGFCYVND VLGILELLK +QRVLY+DID+HHGDGVE AFY TDRVMT
Sbjct: 164 HAKQSEASGFCYVNDCVLGILELLKTYQRVLYVDIDIHHGDGVEEAFYLTDRVMT 218
>UniRef50_Q0V6A5 Cluster: Putative uncharacterized protein; n=2;
Pleosporales|Rep: Putative uncharacterized protein -
Phaeosphaeria nodorum (Septoria nodorum)
Length = 507
Score = 192 bits (468), Expect = 8e-48
Identities = 91/171 (53%), Positives = 113/171 (66%), Gaps = 3/171 (1%)
Frame = +1
Query: 274 HPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVSEY 453
HPMKP R+ +T L++ YGL M++Y P A E+ FH +Y+ +L I P N
Sbjct: 80 HPMKPWRLTLTKQLVVAYGLEYTMDLYTPRPANFGELALFHDREYLEYLSKITPQNAQPE 139
Query: 454 NKQMQRFNVG---EDCPVFDGLYEFCQLSAGGSVAAAVKLNKQASEICINWGGGLHHAKK 624
+ Q + G DCPVFDGL+ + L +G S++AA L + S+I INW GGLHHAKK
Sbjct: 140 DPQYISYGFGGDSNDCPVFDGLWNYVSLYSGASMSAAWNLLNKQSDIAINWSGGLHHAKK 199
Query: 625 SEASGFCYVNDIVLGILELLKYHQRVLYIDIDVHHGDGVEXAFYTTDRVMT 777
+ ASGFCYVNDIV+ I LL HQRVLYIDIDVHHGDGVE AF +TDRV T
Sbjct: 200 NLASGFCYVNDIVIAIQLLLTQHQRVLYIDIDVHHGDGVEQAFESTDRVFT 250
>UniRef50_A4VDD9 Cluster: Histone deacetylase 1, 2 ,3; n=4;
Oligohymenophorea|Rep: Histone deacetylase 1, 2 ,3 -
Tetrahymena thermophila SB210
Length = 473
Score = 192 bits (467), Expect = 1e-47
Identities = 102/210 (48%), Positives = 131/210 (62%), Gaps = 21/210 (10%)
Frame = +1
Query: 211 SKKRVCXXXXXXXXXXXXXQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTK 390
+KK+V + H M P RI MTH+L++ YG+Y+ +++Y +AT +E+ +
Sbjct: 3 TKKKVAYFYNNEIGNYNYGKLHLMNPKRISMTHSLIVGYGVYKDLDVYTTREATKEEIMQ 62
Query: 391 FHSDDYIRFLRS-------------------IRPDNVSEYNKQMQR-FNVGEDCPVFDGL 510
FH DY+ +L + I D ++ +K+ Q +V DCP FDGL
Sbjct: 63 FHDQDYVEYLSNYVSSSKIDFLKKNGCSIPLIDEDAKNDSDKKKQYGIDVQADCPGFDGL 122
Query: 511 YEFCQLSAGG-SVAAAVKLNKQASEICINWGGGLHHAKKSEASGFCYVNDIVLGILELLK 687
Y F QLS GG S+ AA + A++I INWGGGLHHAKK EA GFCYVNDIV+ ILELLK
Sbjct: 123 YTFSQLSTGGGSIDAAHLIINNAADIAINWGGGLHHAKKGEAYGFCYVNDIVICILELLK 182
Query: 688 YHQRVLYIDIDVHHGDGVEXAFYTTDRVMT 777
RVLYIDIDVHHGDGVE AFYTT+RVMT
Sbjct: 183 VFPRVLYIDIDVHHGDGVEEAFYTTNRVMT 212
>UniRef50_A0PAD5 Cluster: Putative uncharacterized protein; n=2;
Ipomoea trifida|Rep: Putative uncharacterized protein -
Ipomoea trifida (Morning glory)
Length = 496
Score = 182 bits (443), Expect = 9e-45
Identities = 78/102 (76%), Positives = 89/102 (87%)
Frame = +1
Query: 472 FNVGEDCPVFDGLYEFCQLSAGGSVAAAVKLNKQASEICINWGGGLHHAKKSEASGFCYV 651
+N+GEDCPVFD L+EFCQ+ AGG++ AA +LN Q ++ INW GGLHHAKK EASGFCY+
Sbjct: 105 YNLGEDCPVFDNLFEFCQIYAGGTIDAARRLNNQLCDVAINWAGGLHHAKKCEASGFCYI 164
Query: 652 NDIVLGILELLKYHQRVLYIDIDVHHGDGVEXAFYTTDRVMT 777
ND+VLGILELLKYH RVLYIDIDVHHGDGVE AFY TDRVMT
Sbjct: 165 NDLVLGILELLKYHPRVLYIDIDVHHGDGVEEAFYFTDRVMT 206
>UniRef50_Q94D35 Cluster: Histone deacetylase-like; n=9; Oryza
sativa|Rep: Histone deacetylase-like - Oryza sativa
subsp. japonica (Rice)
Length = 481
Score = 173 bits (420), Expect = 5e-42
Identities = 89/201 (44%), Positives = 117/201 (58%), Gaps = 13/201 (6%)
Frame = +1
Query: 214 KKRVCXXXXXXXXXXXXXQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKF 393
K+RVC +GH M PHR+ M HNL+ YG+ M R ATA E+ F
Sbjct: 19 KRRVCYYYDPGISTVDYGEGHVMVPHRVTMAHNLVAAYGMLGDMRRLRTAPATAAELADF 78
Query: 394 HSDDYIRFLRSIRPDN------VSEYNKQMQRFNV-------GEDCPVFDGLYEFCQLSA 534
H + Y+ L+ + PD V + + + V G D PVFD L+++C +
Sbjct: 79 HDEGYLALLQDLTPDGCGGDDGVGDMARARGIYAVEGKGGGRGVDNPVFDRLWDYCLRYS 138
Query: 535 GGSVAAAVKLNKQASEICINWGGGLHHAKKSEASGFCYVNDIVLGILELLKYHQRVLYID 714
GGS+AAA L ++I INW GG+HHA + A GFCYVNDIVL I ELL + +RVLY+D
Sbjct: 139 GGSLAAARTLGSGTADIAINWSGGMHHACRGGARGFCYVNDIVLAIRELLAHFRRVLYVD 198
Query: 715 IDVHHGDGVEXAFYTTDRVMT 777
IDVHHGDGV+ AF ++RVMT
Sbjct: 199 IDVHHGDGVQAAFEASNRVMT 219
>UniRef50_A0CXG2 Cluster: Chromosome undetermined scaffold_30, whole
genome shotgun sequence; n=4; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_30,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 482
Score = 171 bits (417), Expect = 1e-41
Identities = 97/225 (43%), Positives = 129/225 (57%), Gaps = 36/225 (16%)
Frame = +1
Query: 211 SKKRVCXXXXXXXXXXXXXQGHPMKPHRIRMTHNLLLNYG-LYRKMEIYRPHKATADEMT 387
S +RV + HPMKP RI M H+L++N+G LYR +++Y +A +E+
Sbjct: 8 SSRRVAYFYNRLIGKFHYGKEHPMKPKRIAMAHSLIVNFGQLYRSLDVYLIREAQLEELQ 67
Query: 388 KFHSDDYIRFLRS--------------------IRPDNV-SEY--------NKQMQRFN- 477
KFH +Y+ +L + P+N+ EY NK + N
Sbjct: 68 KFHDPEYVTYLSQYMSENKVNFVKEYCSTNNDGVIPENLLEEYRLITKWSQNKNTKNLNS 127
Query: 478 ---VGE--DCPVFDGLYEFCQLSAGGSVAAAVKLNKQASEICINWGGGLHHAKKSEASGF 642
VG+ D P F GL+ +CQ SAG S+ A + ++I INW GGLHHAKK EA+GF
Sbjct: 128 EYKVGDSADNPTFSGLFSYCQFSAGASIDCAHTILTGQADIAINWSGGLHHAKKKEAAGF 187
Query: 643 CYVNDIVLGILELLKYHQRVLYIDIDVHHGDGVEXAFYTTDRVMT 777
CY+NDIVL ILELL+ + RVLY+DID HHGDGVE AFY T+RVMT
Sbjct: 188 CYINDIVLCILELLRIYVRVLYVDIDCHHGDGVEEAFYLTNRVMT 232
>UniRef50_UPI0000587266 Cluster: PREDICTED: similar to Histone
deacetylase 8; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to Histone deacetylase 8 -
Strongylocentrotus purpuratus
Length = 654
Score = 164 bits (399), Expect = 2e-39
Identities = 78/168 (46%), Positives = 107/168 (63%), Gaps = 1/168 (0%)
Frame = +1
Query: 277 PMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVSEYN 456
P P R M H L+ Y L + P AT DE+ FHS +YI FL + + SE +
Sbjct: 307 PKIPKRASMVHTLIEAYDLLDHVTPVSPEFATKDELLTFHSQEYIEFLERVNLEEDSEKD 366
Query: 457 KQM-QRFNVGEDCPVFDGLYEFCQLSAGGSVAAAVKLNKQASEICINWGGGLHHAKKSEA 633
+++ Q+F +G DCP +Y+F +L AG S++ A L +Q I INW GG HHA++ EA
Sbjct: 367 EELKQQFGLGYDCPSLPLVYDFVRLVAGASLSCAKALIQQKCRIAINWNGGWHHARRDEA 426
Query: 634 SGFCYVNDIVLGILELLKYHQRVLYIDIDVHHGDGVEXAFYTTDRVMT 777
+GFCYVNDIVL IL+L ++ RVLY+D+D+HHGD V+ AF T +VMT
Sbjct: 427 AGFCYVNDIVLAILKLKEHFNRVLYVDLDLHHGDAVDDAFIFTPKVMT 474
>UniRef50_Q9BY41 Cluster: Histone deacetylase 8; n=40;
Eumetazoa|Rep: Histone deacetylase 8 - Homo sapiens
(Human)
Length = 377
Score = 163 bits (395), Expect = 6e-39
Identities = 70/164 (42%), Positives = 107/164 (65%)
Frame = +1
Query: 286 PHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVSEYNKQM 465
P R M H+L+ Y L+++M I +P A+ +EM FH+D Y++ L+ + + ++ +
Sbjct: 35 PKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEGDDDHPDSI 94
Query: 466 QRFNVGEDCPVFDGLYEFCQLSAGGSVAAAVKLNKQASEICINWGGGLHHAKKSEASGFC 645
+ + +G DCP +G++++ G ++ AA L ++ INW GG HHAKK EASGFC
Sbjct: 95 E-YGLGYDCPATEGIFDYAAAIGGATITAAQCLIDGMCKVAINWSGGWHHAKKDEASGFC 153
Query: 646 YVNDIVLGILELLKYHQRVLYIDIDVHHGDGVEXAFYTTDRVMT 777
Y+ND VLGIL L + +R+LY+D+D+HHGDGVE AF T +VMT
Sbjct: 154 YLNDAVLGILRLRRKFERILYVDLDLHHGDGVEDAFSFTSKVMT 197
>UniRef50_A3C9I4 Cluster: Putative uncharacterized protein; n=6;
Oryza sativa|Rep: Putative uncharacterized protein -
Oryza sativa subsp. japonica (Rice)
Length = 449
Score = 157 bits (380), Expect = 4e-37
Identities = 78/165 (47%), Positives = 106/165 (64%), Gaps = 6/165 (3%)
Frame = +1
Query: 301 MTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDN----VSEYNKQMQ 468
M H+L+ YG+ M R AT E+ +FHS +Y+ LR + P++ + K
Sbjct: 1 MAHSLVGVYGMLGDMSRLRTRPATEAEIRRFHSPEYVDLLRDLTPESYFNDAALRQKAED 60
Query: 469 RFNVG--EDCPVFDGLYEFCQLSAGGSVAAAVKLNKQASEICINWGGGLHHAKKSEASGF 642
+G +DCP FD L+++C+ AGGS+AAA L AS+I INW GG+HHA +A+GF
Sbjct: 61 DHGIGGKDDCPAFDRLWKYCRGYAGGSLAAARALVDGASDIAINWSGGMHHASACKATGF 120
Query: 643 CYVNDIVLGILELLKYHQRVLYIDIDVHHGDGVEXAFYTTDRVMT 777
CYVNDIVL I ELL +RV+Y+DID HHGDGV+ AF ++RVMT
Sbjct: 121 CYVNDIVLAINELLGTFRRVIYVDIDAHHGDGVQNAFLDSNRVMT 165
>UniRef50_UPI0000D55D9C Cluster: PREDICTED: similar to histone
deacetylase 8; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to histone deacetylase 8 - Tribolium castaneum
Length = 376
Score = 150 bits (364), Expect = 3e-35
Identities = 69/170 (40%), Positives = 107/170 (62%), Gaps = 3/170 (1%)
Frame = +1
Query: 277 PMKPHRIRMTHNLLLNYGLY--RKMEIYRPHKATADEMTKFHSDDYIRFLRSIRP-DNVS 447
P +R + +L+ +Y + K+ + AT DE+ FHS YI FL+ + DN
Sbjct: 23 PTMLNRASIVQDLINSYRILCSDKVLTVQSRDATEDELKLFHSSSYINFLKKVNNLDNFE 82
Query: 448 EYNKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAAVKLNKQASEICINWGGGLHHAKKS 627
+Y+++ Q F +G DCP+ + Y+F + AGGS+ AA L K ++ INW GG HHA++
Sbjct: 83 DYDEEQQEFGLGYDCPILEHNYDFIKTIAGGSITAAKILCKTDYKVVINWFGGWHHAQRD 142
Query: 628 EASGFCYVNDIVLGILELLKYHQRVLYIDIDVHHGDGVEXAFYTTDRVMT 777
A+GFCYVNDIVL I +L + ++LY+D+D+HHGDGV+ AF + +++T
Sbjct: 143 SAAGFCYVNDIVLAIQKLTEKFTKILYLDLDIHHGDGVQNAFELSKKILT 192
>UniRef50_Q8SQN9 Cluster: HISTONE DEACETYLASE; n=1; Encephalitozoon
cuniculi|Rep: HISTONE DEACETYLASE - Encephalitozoon
cuniculi
Length = 344
Score = 150 bits (364), Expect = 3e-35
Identities = 79/168 (47%), Positives = 107/168 (63%)
Frame = +1
Query: 274 HPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVSEY 453
HPMKP R +TH+L+ ++GL +KM I +P ++ +H+++Y+ N+ +
Sbjct: 20 HPMKPFRTVVTHSLVKSFGLDKKMTIVKPE---VFPLSSYHTEEYL--------GNLGK- 67
Query: 454 NKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAAVKLNKQASEICINWGGGLHHAKKSEA 633
N DCP F GL FC+L S+ +A+ L++ A INW GGLHHA K+
Sbjct: 68 -------NETPDCPNFIGLPRFCELYGSASINSAMILSEGAYSTVINWSGGLHHAHKAIP 120
Query: 634 SGFCYVNDIVLGILELLKYHQRVLYIDIDVHHGDGVEXAFYTTDRVMT 777
SGFC+VNDIVL ILELLK ++RV+YIDIDVHHGDGVE AF DRV+T
Sbjct: 121 SGFCHVNDIVLAILELLKTYRRVMYIDIDVHHGDGVEEAFLECDRVLT 168
>UniRef50_Q4QCE7 Cluster: Histone deacetylase, putative; n=7;
Trypanosomatidae|Rep: Histone deacetylase, putative -
Leishmania major
Length = 428
Score = 150 bits (363), Expect = 4e-35
Identities = 71/168 (42%), Positives = 100/168 (59%)
Frame = +1
Query: 274 HPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVSEY 453
H MKP+R+ ++ + + P +E+ +H+D Y+ L + +
Sbjct: 43 HAMKPYRVLAAMEIVRSLKIDAHCRTVVPPLVKVEELMAYHTDTYLANL-GLHSCRSWLW 101
Query: 454 NKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAAVKLNKQASEICINWGGGLHHAKKSEA 633
N + + DCP +GL E +A G++ AV LN ++ ++WGGG+HH+K E
Sbjct: 102 NAETSKVFFSGDCPPVEGLMEHSIATASGTLMGAVLLNSGQVDVAVHWGGGMHHSKCGEC 161
Query: 634 SGFCYVNDIVLGILELLKYHQRVLYIDIDVHHGDGVEXAFYTTDRVMT 777
SGFCYVNDIVLGILELLK H RVLY+DID+HHGDGV+ AF T+DRV T
Sbjct: 162 SGFCYVNDIVLGILELLKCHDRVLYVDIDMHHGDGVDEAFCTSDRVFT 209
>UniRef50_Q98RL4 Cluster: Histone deacetylase; n=1; Guillardia
theta|Rep: Histone deacetylase - Guillardia theta
(Cryptomonas phi)
Length = 374
Score = 149 bits (361), Expect = 8e-35
Identities = 76/167 (45%), Positives = 100/167 (59%), Gaps = 1/167 (0%)
Frame = +1
Query: 274 HPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVSEY 453
HPM+P R+ MT L+ +YG+ + + I R K T EM HS I I+ N
Sbjct: 23 HPMQPIRLSMTSELIYSYGMEKFLRIIRTEKKTNSEMFNIHSS--IFEFNVIKKKNFESI 80
Query: 454 NK-QMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAAVKLNKQASEICINWGGGLHHAKKSE 630
N + +++ DCP+F GL E+ L + S+ + +L +I INW GGLHH+K E
Sbjct: 81 NYITIDKYDA--DCPIFKGLNEYLLLYSSASLLSLDELTNNNCQIAINWSGGLHHSKIDE 138
Query: 631 ASGFCYVNDIVLGILELLKYHQRVLYIDIDVHHGDGVEXAFYTTDRV 771
SGFCY+NDI L IL LLK+ +LYIDIDVHHGDGVE FY T+RV
Sbjct: 139 KSGFCYLNDINLCILNLLKHFNYILYIDIDVHHGDGVEEVFYATNRV 185
>UniRef50_Q4QAJ4 Cluster: Histone deacetylase, putative; n=3;
Leishmania|Rep: Histone deacetylase, putative -
Leishmania major
Length = 536
Score = 149 bits (360), Expect = 1e-34
Identities = 80/181 (44%), Positives = 108/181 (59%), Gaps = 11/181 (6%)
Frame = +1
Query: 268 QGHPMKPHRIRMTHNLLLNYGLYRK--MEIYRPHKATADEMTKFHSDDYIRFLRS---IR 432
+GH M+P R+R H L+ + GL M + ATA+EM FH Y+ LR I
Sbjct: 100 EGHLMRPSRVRALHALVHSLGLDNAECMTVCHARPATAEEMGAFHRSAYLECLRQAPVIC 159
Query: 433 PDNVSEYNKQMQR-FNV-----GEDCPVFDGLYEFCQLSAGGSVAAAVKLNKQASEICIN 594
+ + E + Q+ F+V DCP+F ++ AG S+A A L + + + +N
Sbjct: 160 GNPLDEMSLAFQKEFDVPFASQDSDCPLFPEVWALVSSQAGASLACAEALVRGDATVAMN 219
Query: 595 WGGGLHHAKKSEASGFCYVNDIVLGILELLKYHQRVLYIDIDVHHGDGVEXAFYTTDRVM 774
W GG+HHA + ASGFC+VNDIVL I LL+Y+QRVLY+D+DVHHGDGVE AFY RVM
Sbjct: 220 WAGGMHHAAAAHASGFCFVNDIVLCIRRLLRYYQRVLYVDLDVHHGDGVEGAFYGNHRVM 279
Query: 775 T 777
T
Sbjct: 280 T 280
>UniRef50_Q17CU3 Cluster: Histone deacetylase; n=2; Aedes
aegypti|Rep: Histone deacetylase - Aedes aegypti
(Yellowfever mosquito)
Length = 355
Score = 144 bits (349), Expect = 2e-33
Identities = 67/164 (40%), Positives = 102/164 (62%), Gaps = 1/164 (0%)
Frame = +1
Query: 289 HRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIR-PDNVSEYNKQM 465
+R + L+ +Y L + ++ P + T +++ FHS DY+ L+ D++ E ++
Sbjct: 9 NRSAVVDELVRSYDLLQFCKVISPKRGTLEDLLSFHSSDYVECLKRYNNEDDIEEVTDEL 68
Query: 466 QRFNVGEDCPVFDGLYEFCQLSAGGSVAAAVKLNKQASEICINWGGGLHHAKKSEASGFC 645
Q F + DCP+ + +Y+F S GS +AV + + I INW GG HHA++ +A+GFC
Sbjct: 69 QEFGLAYDCPMIEKVYDFVS-SVVGSTLSAVDAILEGASIAINWHGGWHHAQRDKAAGFC 127
Query: 646 YVNDIVLGILELLKYHQRVLYIDIDVHHGDGVEXAFYTTDRVMT 777
YVNDIV+GI +L Q+VLY+D+DVHHGDGVE AF + VMT
Sbjct: 128 YVNDIVIGIHKLRTKFQKVLYLDLDVHHGDGVEDAFSFSKYVMT 171
>UniRef50_Q6C3Y5 Cluster: Similar to CA1453|CaHOS1 Candida albicans
CaHOS1 Putative histone deacetylase; n=1; Yarrowia
lipolytica|Rep: Similar to CA1453|CaHOS1 Candida
albicans CaHOS1 Putative histone deacetylase - Yarrowia
lipolytica (Candida lipolytica)
Length = 424
Score = 137 bits (331), Expect = 3e-31
Identities = 65/168 (38%), Positives = 102/168 (60%)
Frame = +1
Query: 271 GHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVSE 450
G P R + +LL+ L++ ++ ATA E+ ++HS +Y+ ++ SE
Sbjct: 63 GRPSNEGRAALVDSLLVALQLHKSYKLIPITPATAAELQRYHSLEYVS---AVLKKGQSE 119
Query: 451 YNKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAAVKLNKQASEICINWGGGLHHAKKSE 630
K + + + DCP+F GL + +L AG +++ A +L ++CINW GG HH K+S
Sbjct: 120 --KTLDKMGLIHDCPIFPGLDAYVKLVAGSTLSCARQLMSGQHQLCINWYGGRHHGKRSA 177
Query: 631 ASGFCYVNDIVLGILELLKYHQRVLYIDIDVHHGDGVEXAFYTTDRVM 774
ASGFCYVND+VLGI E+ K +Q+++YID+D+HHGD V AF + V+
Sbjct: 178 ASGFCYVNDVVLGIQEMRKQYQKIMYIDVDLHHGDAVSAAFLHSKNVL 225
>UniRef50_Q74DU3 Cluster: Histone deacetylase/AcuC/AphA family
protein; n=7; Desulfuromonadales|Rep: Histone
deacetylase/AcuC/AphA family protein - Geobacter
sulfurreducens
Length = 385
Score = 130 bits (315), Expect = 3e-29
Identities = 70/171 (40%), Positives = 103/171 (60%), Gaps = 3/171 (1%)
Frame = +1
Query: 274 HPMKPHRIRMTHNLLLNYGLYR--KMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVS 447
HP K R + L+ YGL ++I +A + + FH+ DY+ LR + S
Sbjct: 22 HPFKIQRFILAFELMRAYGLMELPNVKILDCPRAAEEALLTFHAPDYLDRLREF---SES 78
Query: 448 EYNKQMQRFNVGE-DCPVFDGLYEFCQLSAGGSVAAAVKLNKQASEICINWGGGLHHAKK 624
+ + R+ +G+ D PVF GLY++ +L AGG++ AA + ++ +I N GG HHA +
Sbjct: 79 DDARADFRYGLGDLDNPVFRGLYDWARLGAGGTIEAARLVAEEGYDIAFNLAGGWHHAHR 138
Query: 625 SEASGFCYVNDIVLGILELLKYHQRVLYIDIDVHHGDGVEXAFYTTDRVMT 777
++ASGF Y+ND V+ I LL+ RV Y+DID HHGDGV+ AFY TDRV+T
Sbjct: 139 AKASGFSYLNDAVVAINLLLEKGLRVAYLDIDAHHGDGVQEAFYDTDRVLT 189
>UniRef50_A0B926 Cluster: Histone deacetylase superfamily; n=1;
Methanosaeta thermophila PT|Rep: Histone deacetylase
superfamily - Methanosaeta thermophila (strain DSM 6194
/ PT) (Methanothrixthermophila (strain DSM 6194 / PT))
Length = 370
Score = 127 bits (307), Expect = 3e-28
Identities = 70/172 (40%), Positives = 97/172 (56%), Gaps = 4/172 (2%)
Frame = +1
Query: 274 HPMKPHRIRMTHNLLLNYGLYR--KMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVS 447
HP++P RI +T+ ++ YG + E+ P+ A+ D++ H YI+ ++ RPD
Sbjct: 19 HPLQPARIMLTYRMIEEYGFFLGYDTEVQMPYYASEDDLLMVHDPGYIQAVKEERPDPAL 78
Query: 448 EYNKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAAVKLNKQASEICI--NWGGGLHHAK 621
++ D PVF G+Y+ L AG S+ AA ++ ASE C+ N GGLHHA
Sbjct: 79 GLDEP--------DTPVFPGIYDASALIAGASIEAAKRV---ASEPCVAFNLAGGLHHAF 127
Query: 622 KSEASGFCYVNDIVLGILELLKYHQRVLYIDIDVHHGDGVEXAFYTTDRVMT 777
+ A+GFC ND LGI L K RVLYIDID HHGDGV+ FY V+T
Sbjct: 128 PARAAGFCVFNDCALGIRTLRKRFDRVLYIDIDAHHGDGVQYIFYEDPSVLT 179
>UniRef50_Q3A415 Cluster: Deacetylase; n=1; Pelobacter carbinolicus
DSM 2380|Rep: Deacetylase - Pelobacter carbinolicus
(strain DSM 2380 / Gra Bd 1)
Length = 381
Score = 123 bits (296), Expect = 6e-27
Identities = 65/173 (37%), Positives = 98/173 (56%), Gaps = 3/173 (1%)
Frame = +1
Query: 268 QGHPMKPHRIRMTHNLLLNYGLYRK--MEIYRPHKATADEMTKFHSDDYIRFLRSIRPDN 441
QGHP K R +T+ LL L + + + +AT E+ FH DY+R L+ D+
Sbjct: 20 QGHPFKVERFALTYALLDALHLLSRPGIRLIEAPRATYAELLSFHHPDYLRTLQEFSCDS 79
Query: 442 VSEYNKQMQRFNVGE-DCPVFDGLYEFCQLSAGGSVAAAVKLNKQASEICINWGGGLHHA 618
+ RF +G+ + PVF+ L+++ L GG++ AA ++ + N GG HHA
Sbjct: 80 TRRADF---RFGLGDMENPVFEDLFDWVSLCCGGTMEAARQVLDKNCRCAFNMAGGWHHA 136
Query: 619 KKSEASGFCYVNDIVLGILELLKYHQRVLYIDIDVHHGDGVEXAFYTTDRVMT 777
+ ASGF Y+ND V+ I ++ +V Y+D+D HHGDGV+ AFY TDRV+T
Sbjct: 137 HAARASGFSYLNDAVVAINSMVARGFKVAYVDLDAHHGDGVQEAFYATDRVLT 189
>UniRef50_A5DN16 Cluster: Putative uncharacterized protein; n=1;
Pichia guilliermondii|Rep: Putative uncharacterized
protein - Pichia guilliermondii (Yeast) (Candida
guilliermondii)
Length = 385
Score = 120 bits (290), Expect = 3e-26
Identities = 65/179 (36%), Positives = 100/179 (55%), Gaps = 12/179 (6%)
Frame = +1
Query: 277 PMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVSE-- 450
P R+ +T +L + ++ AT E+T FH +++ L R NV E
Sbjct: 25 PSNTGRMSLTTSLTRALKVDLGCDVVEAKDATDKELTSFHGKEFVTELLRQRGSNVEEID 84
Query: 451 ------YNK--QMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAAVKLNKQASE--ICINWG 600
+NK +++F + DCP+F GL + + AG S+ +A KL + + INW
Sbjct: 85 DEKEAHFNKTSHLEKFGLVYDCPLFCGLDRYVRAVAGSSINSARKLLSDTKDHLLAINWY 144
Query: 601 GGLHHAKKSEASGFCYVNDIVLGILELLKYHQRVLYIDIDVHHGDGVEXAFYTTDRVMT 777
GG HH +K+ A+GFCYVNDIV+ I L + +++V Y+D+D+HHGDGVE AF + V+T
Sbjct: 145 GGRHHCQKNRAAGFCYVNDIVMAINVLRRRYRKVFYLDLDLHHGDGVESAFEHSSSVLT 203
>UniRef50_A5H660 Cluster: Histone deacetylase 8; n=3;
Schistosoma|Rep: Histone deacetylase 8 - Schistosoma
mansoni (Blood fluke)
Length = 440
Score = 120 bits (289), Expect = 4e-26
Identities = 63/149 (42%), Positives = 90/149 (60%), Gaps = 15/149 (10%)
Frame = +1
Query: 376 DEMTKFHSDDYIRFLRSIRPDNVSEYNKQ------MQRFNVGEDCPVFDGLYEFCQLSAG 537
+ +T FHS +Y+ L+ ++ + E M F++ DCP F ++++ +
Sbjct: 57 EAVTAFHSTEYVDALKKLQMLHCEEKELTADDELLMDSFSLNYDCPGFPSVFDYSLAAVQ 116
Query: 538 GSVAAAVKLNKQASEICINWGGGLHHAKKSEASGFCYVNDIVLGILELL---------KY 690
GS+AAA L + E+ INWGGG HHAK+SEASGFCY+NDIVL I L+
Sbjct: 117 GSLAAASALICRHCEVVINWGGGWHHAKRSEASGFCYLNDIVLAIHRLVSSTPPETSPNR 176
Query: 691 HQRVLYIDIDVHHGDGVEXAFYTTDRVMT 777
RVLY+D+D+HHGDGVE AF+ + RV+T
Sbjct: 177 QTRVLYVDLDLHHGDGVEEAFWYSPRVVT 205
>UniRef50_A0K0A0 Cluster: Histone deacetylase superfamily; n=2;
Arthrobacter|Rep: Histone deacetylase superfamily -
Arthrobacter sp. (strain FB24)
Length = 407
Score = 119 bits (286), Expect = 9e-26
Identities = 68/174 (39%), Positives = 95/174 (54%), Gaps = 5/174 (2%)
Frame = +1
Query: 271 GHPMKPHRIRMTHNLLLNYGLYR--KMEIYRPHKATADEMTKFHSDDYIRFLR--SIRPD 438
GHPM P R+ +T L + GL + + P A DE+ HS +++ +R S+ PD
Sbjct: 30 GHPMAPERMELTARLARSLGLLDLGHVTVAAPEVAGDDELCTVHSAEFVAAVRRVSLNPD 89
Query: 439 NVSEYNKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAAVKLNKQASEICINWGGGLHHA 618
++R ED P F G++E AGGS+ AA + ++ +N+GGG+HHA
Sbjct: 90 E-----PDLERGLGTEDDPAFAGMHEASARLAGGSLMAASAILDGSAVRAVNFGGGMHHA 144
Query: 619 KKSEASGFCYVNDIVLGILELLKYH-QRVLYIDIDVHHGDGVEXAFYTTDRVMT 777
K ASGFC ND L I +LL QRV YID+D HHGDG + F+ RV+T
Sbjct: 145 AKERASGFCIYNDAALAIQKLLDGGLQRVAYIDVDAHHGDGTQSIFWDDPRVLT 198
>UniRef50_P39067 Cluster: Acetoin utilization protein acuC; n=25;
Bacillaceae|Rep: Acetoin utilization protein acuC -
Bacillus subtilis
Length = 387
Score = 117 bits (282), Expect = 3e-25
Identities = 63/172 (36%), Positives = 93/172 (54%), Gaps = 2/172 (1%)
Frame = +1
Query: 268 QGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVS 447
Q HP R+ +T++LL + +I P A+ +E++ H+DDYI+ ++ +
Sbjct: 19 QEHPFNQQRVLLTYDLLKTINAFDDGDIVTPRLASEEELSLVHTDDYIQAVKLAGAGKLP 78
Query: 448 EYNKQMQRFNVG-EDCPVFDGLYEFCQLSAGGSVAAAVKLNKQASEICINWGGGLHHAKK 624
++ + + +G ED PVF G++E L GG++ AA + + N GGGLHH +
Sbjct: 79 A--EEGESYGLGTEDTPVFAGMHEAASLLVGGTLTAADWVMSGQALHAANLGGGLHHGFR 136
Query: 625 SEASGFCYVNDIVLGILELLK-YHQRVLYIDIDVHHGDGVEXAFYTTDRVMT 777
ASGFC ND + I + K Y RVLYID D HHGDGV+ FY V T
Sbjct: 137 GRASGFCIYNDSAVAIQYIQKKYSARVLYIDTDAHHGDGVQFTFYDNPDVCT 188
>UniRef50_Q0S1K3 Cluster: Possible acetoin dehydrogenase; n=3;
Bacteria|Rep: Possible acetoin dehydrogenase -
Rhodococcus sp. (strain RHA1)
Length = 423
Score = 117 bits (281), Expect = 4e-25
Identities = 61/170 (35%), Positives = 94/170 (55%), Gaps = 2/170 (1%)
Frame = +1
Query: 274 HPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVSEY 453
HPM P R+ +T +L + G+ +E+ RP A+ ++ + H+ Y+ ++ S
Sbjct: 35 HPMNPTRLELTMSLARSLGILEGVELLRPAAASDADLLRIHTPAYVEAVKQAGHSATSGV 94
Query: 454 NKQMQRFNVG-EDCPVFDGLYEFCQLSAGGSVAAAVKLNKQASEICINWGGGLHHAKKSE 630
+G ED PVF ++E + AGGS+AAA ++ + ++ GGG+HHA
Sbjct: 95 LGADAPHGLGTEDNPVFPQMHEASAILAGGSLAAAQEIAAGRTRRAVSIGGGMHHAMPDW 154
Query: 631 ASGFCYVNDIVLGILELLKY-HQRVLYIDIDVHHGDGVEXAFYTTDRVMT 777
ASGFC ND+ + I LL + R+ YID+D HHGDGV+ AF RV+T
Sbjct: 155 ASGFCVYNDVAIAISWLLDHGFDRIAYIDVDAHHGDGVQHAFAHDPRVLT 204
>UniRef50_Q6BS96 Cluster: Similar to CA1453|CaHOS1 Candida albicans
CaHOS1; n=1; Debaryomyces hansenii|Rep: Similar to
CA1453|CaHOS1 Candida albicans CaHOS1 - Debaryomyces
hansenii (Yeast) (Torulaspora hansenii)
Length = 469
Score = 113 bits (272), Expect = 5e-24
Identities = 52/115 (45%), Positives = 75/115 (65%), Gaps = 5/115 (4%)
Frame = +1
Query: 448 EYNKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAAVKLNKQ-----ASEICINWGGGLH 612
E N +++ + + DC +F + E+ L A S+ AA +L K+ A I INW GG H
Sbjct: 172 EDNAELETYGLLHDCYIFPFMSEYVNLVAASSIQAATRLTKERKDNRAQNIVINWYGGRH 231
Query: 613 HAKKSEASGFCYVNDIVLGILELLKYHQRVLYIDIDVHHGDGVEXAFYTTDRVMT 777
H KK++A+GFCY+NDIVL I L + ++R+ Y+D+D+HHGDGVE AF + VMT
Sbjct: 232 HCKKNKAAGFCYINDIVLSINVLRRNYRRIFYLDLDLHHGDGVESAFEFSKNVMT 286
>UniRef50_Q4R7V0 Cluster: Testis cDNA clone: QtsA-14323, similar to
human histone deacetylase 1 (HDAC1),; n=1; Macaca
fascicularis|Rep: Testis cDNA clone: QtsA-14323, similar
to human histone deacetylase 1 (HDAC1), - Macaca
fascicularis (Crab eating macaque) (Cynomolgus monkey)
Length = 163
Score = 112 bits (269), Expect = 1e-23
Identities = 51/116 (43%), Positives = 81/116 (69%)
Frame = -2
Query: 615 MMEATTPVYANF*GLLIQFYSCCN*TPSR*LTKFIQAIKNWTIFTYIKSLHLFVVLRNIV 436
M++A +P++++ LLI+F+S C+ T SR LT+ Q +K WT+ T ++SLHL VLR+++
Sbjct: 1 MVQALSPIHSDVRLLLIKFHSTCHRTTSRQLTELKQVVKYWTVLTKVESLHLLAVLRHVI 60
Query: 435 RSNRTQESNVII*MEFCHFISCGFVRPINLHFSIESIVEE*IVGHTYAVRFHWMPL 268
++ QE NV++ M H +S GFVR I+ HF +E+IVE+ I+ H +VR HW+ L
Sbjct: 61 WTDGAQEFNVVVAMVLGHLLSIGFVRAIDFHFLLETIVEQQIMSHADSVRLHWVAL 116
>UniRef50_O67135 Cluster: Acetoin utilization protein; n=2; Aquifex
aeolicus|Rep: Acetoin utilization protein - Aquifex
aeolicus
Length = 375
Score = 109 bits (262), Expect = 8e-23
Identities = 61/170 (35%), Positives = 93/170 (54%), Gaps = 2/170 (1%)
Frame = +1
Query: 268 QGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVS 447
+ HP+K R+ + L L + E+ + AT +E+ FH++DYI L
Sbjct: 19 KNHPLKIPRVSLLLRFLDAMNLIDEKELIKSRPATKEELLLFHTEDYINTLMEAERCQCV 78
Query: 448 EYNKQMQRFNVGE-DCPVFDGLYEFCQLSAGGSVAAAVKLNKQASEICINWGGGLHHAKK 624
+ +++N+G + PV ++ L+ G +V A + K + N GG+HHA K
Sbjct: 79 PKGAR-EKYNIGGYENPVSYAMFTGSSLATGSTVQAIEEFLK--GNVAFNPAGGMHHAFK 135
Query: 625 SEASGFCYVNDIVLGILELLKY-HQRVLYIDIDVHHGDGVEXAFYTTDRV 771
S A+GFCY+ND +GI L K +R+LYID+D HH DGV+ AFY TD+V
Sbjct: 136 SRANGFCYINDPAVGIEYLRKKGFKRILYIDLDAHHCDGVQEAFYDTDQV 185
>UniRef50_Q4P6M9 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 568
Score = 86.6 bits (205), Expect(2) = 8e-23
Identities = 38/73 (52%), Positives = 49/73 (67%)
Frame = +1
Query: 469 RFNVGEDCPVFDGLYEFCQLSAGGSVAAAVKLNKQASEICINWGGGLHHAKKSEASGFCY 648
+F + +DCP F+GL + L AG ++ AA L ++I I W GG HHAKKS ASGFCY
Sbjct: 192 QFGLQDDCPAFEGLQQHVSLVAGAAITAAELLATGQADIAIAWDGGRHHAKKSSASGFCY 251
Query: 649 VNDIVLGILELLK 687
+ND+VL IL L K
Sbjct: 252 INDVVLAILSLRK 264
Score = 43.6 bits (98), Expect(2) = 8e-23
Identities = 18/32 (56%), Positives = 24/32 (75%)
Frame = +1
Query: 682 LKYHQRVLYIDIDVHHGDGVEXAFYTTDRVMT 777
+K RVLY+D D+H GDGVE AF++T V+T
Sbjct: 295 IKRVDRVLYLDFDLHWGDGVEEAFHSTSNVLT 326
>UniRef50_UPI000050FC36 Cluster: COG0123: Deacetylases, including
yeast histone deacetylase and acetoin utilization
protein; n=1; Brevibacterium linens BL2|Rep: COG0123:
Deacetylases, including yeast histone deacetylase and
acetoin utilization protein - Brevibacterium linens BL2
Length = 401
Score = 107 bits (257), Expect = 3e-22
Identities = 58/172 (33%), Positives = 92/172 (53%), Gaps = 4/172 (2%)
Frame = +1
Query: 274 HPMKPHRIRMTHNLLLNYGLYR--KMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVS 447
HPM P R+ +T L +++GL+ + ++ D + K H D+I ++ I D
Sbjct: 26 HPMHPLRLDLTATLAMDFGLFDADNVHVHGVSDVEEDTLAKLHDADFIAAVKQIG-DGAV 84
Query: 448 EYNKQMQRFNVG-EDCPVFDGLYEFCQLSAGGSVAAAVKLNKQASEICINWGGGLHHAKK 624
++ +++ +G ED P F+ ++ + GSV +A + +N+ GG+HHA
Sbjct: 85 LSDEDARKYGIGTEDVPGFENMHAASAMLFQGSVDSARAIISGDYSHAVNFTGGMHHAMP 144
Query: 625 SEASGFCYVNDIVLGILELL-KYHQRVLYIDIDVHHGDGVEXAFYTTDRVMT 777
ASGFC NDI I E L ++R+ YID+D HHGDGVE F+ RV+T
Sbjct: 145 DHASGFCVYNDIAGAITEFLGAGYERIAYIDLDAHHGDGVEKFFWDDPRVLT 196
>UniRef50_P64375 Cluster: Acetoin utilization protein acuC; n=15;
Staphylococcus|Rep: Acetoin utilization protein acuC -
Staphylococcus aureus (strain Mu50 / ATCC 700699)
Length = 389
Score = 107 bits (257), Expect = 3e-22
Identities = 66/195 (33%), Positives = 94/195 (48%), Gaps = 2/195 (1%)
Frame = +1
Query: 199 MQPHSKKRVCXXXXXXXXXXXXXQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATAD 378
MQ HS K Q HP R+++T LLLN L +I +P AT D
Sbjct: 1 MQQHSSKTAYVYSDKLLQYRFHDQ-HPFNQMRLKLTTELLLNANLLSPEQIVQPRIATGD 59
Query: 379 EMTKFHSDDYIRFLRSIRPDNVSEYNKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAA- 555
E+ H DY+ ++ +SE + N E+ F ++ GG++ A
Sbjct: 60 ELMLIHKYDYVEAIKHASHGIISEDEAKKYGLN-DEENGQFKHMHRHSATIVGGALTLAD 118
Query: 556 VKLNKQASEICINWGGGLHHAKKSEASGFCYVNDIVLGILELLK-YHQRVLYIDIDVHHG 732
+ ++ + C + GGGLHHA+ ASGFC NDI + + K Y+QRVL ID D HHG
Sbjct: 119 LIMSGKVLNGC-HLGGGLHHAQPGRASGFCIYNDIAITAQYIAKEYNQRVLIIDTDAHHG 177
Query: 733 DGVEXAFYTTDRVMT 777
DG + +FY + V T
Sbjct: 178 DGTQWSFYADNHVTT 192
>UniRef50_Q1AX98 Cluster: Histone deacetylase superfamily; n=2;
Bacteria|Rep: Histone deacetylase superfamily -
Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 387
Score = 105 bits (251), Expect = 2e-21
Identities = 61/174 (35%), Positives = 92/174 (52%), Gaps = 4/174 (2%)
Frame = +1
Query: 268 QGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVS 447
+ HP P RIR+T L GL + P + +E+T H+ Y+R ++ + +
Sbjct: 20 EDHPFNPLRIRLTLELCDALGLLDGYDFLAPEPVSEEELTSVHTLTYVRMVQ--QASRGA 77
Query: 448 EYNKQMQRFNVGE-DCPVFDGLYEFCQLSAGGSVAAAVKLNKQASEICINWGGGLHHAKK 624
+++ + +G D P+F G++E C GG+V A + +E + GGLHHA +
Sbjct: 78 GDPERLLDYGLGTPDNPLFAGMHEACSRVVGGTVLACRLVAAGEAEHAMCISGGLHHALR 137
Query: 625 SEASGFCYVNDIVLGILELLKYHQ---RVLYIDIDVHHGDGVEXAFYTTDRVMT 777
S+ASGFC ND + I LLK + RV Y+D D HHGDGV+ FY V+T
Sbjct: 138 SKASGFCIYNDAAVAI-ALLKRERPGIRVAYVDTDAHHGDGVQWMFYEDPEVLT 190
>UniRef50_A7TRW5 Cluster: Putative uncharacterized protein; n=1;
Vanderwaltozyma polyspora DSM 70294|Rep: Putative
uncharacterized protein - Vanderwaltozyma polyspora DSM
70294
Length = 518
Score = 104 bits (250), Expect = 2e-21
Identities = 50/107 (46%), Positives = 72/107 (67%), Gaps = 3/107 (2%)
Frame = +1
Query: 466 QRFNVGEDCPVFDGLYEFCQLSAGGSVAAAVKLNKQASE--ICINWGGGLHHAKKSEASG 639
++FN+ DCP+F L +C++ +G S+ + + K +S+ I INW GG HHA K++ASG
Sbjct: 173 KKFNLEGDCPLFSFLPLYCEVISGASLMLSDFIEKSSSQRTIAINWDGGRHHAIKNKASG 232
Query: 640 FCYVNDIVLGILELLKYH-QRVLYIDIDVHHGDGVEXAFYTTDRVMT 777
FCY+NDIV+ I +L K +V YID D+HHGDGVE AF + + T
Sbjct: 233 FCYINDIVILIQKLRKKGISKVSYIDFDLHHGDGVEKAFRYSSNIQT 279
>UniRef50_Q12214 Cluster: Histone deacetylase HOS1; n=2;
Saccharomyces cerevisiae|Rep: Histone deacetylase HOS1 -
Saccharomyces cerevisiae (Baker's yeast)
Length = 470
Score = 104 bits (250), Expect = 2e-21
Identities = 48/117 (41%), Positives = 70/117 (59%), Gaps = 1/117 (0%)
Frame = +1
Query: 430 RPDNVSEYNKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAAVKLNKQASEICINWGGGL 609
+P + N + +++N+ DCP+F L +CQ+ G ++ L+ I INW GG
Sbjct: 150 KPTDTYILNSETKQYNLEGDCPIFSYLPMYCQVITGATLNLLDHLSPTERLIGINWDGGR 209
Query: 610 HHAKKSEASGFCYVNDIVLGILELLKYH-QRVLYIDIDVHHGDGVEXAFYTTDRVMT 777
HHA K ASGFCY+ND+VL I L K ++ Y+D D+HHGDGVE AF + ++ T
Sbjct: 210 HHAFKQRASGFCYINDVVLLIQRLRKAKLNKITYVDFDLHHGDGVEKAFQYSKQIQT 266
>UniRef50_Q2J786 Cluster: Histone deacetylase superfamily; n=13;
Actinomycetales|Rep: Histone deacetylase superfamily -
Frankia sp. (strain CcI3)
Length = 426
Score = 103 bits (246), Expect = 7e-21
Identities = 62/172 (36%), Positives = 91/172 (52%), Gaps = 4/172 (2%)
Frame = +1
Query: 274 HPMKPHRIRMTHNLLLNYGLYRK--MEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVS 447
HP+ P R+ +T +L ++ G+ + I RP A+ D + H Y+ +R+ PD
Sbjct: 41 HPLHPVRLELTMDLAMSLGVLDAPGIRISRPTLASDDLIGLIHDPVYLSAVRAA-PDPAQ 99
Query: 448 EYNKQMQRFNVGE-DCPVFDGLYEFCQLSAGGSVAAAVKLNKQASEICINWGGGLHHAKK 624
+ F +G D P+F+ ++E L GG++ AA + ++ GGLHHA
Sbjct: 100 ARFAAL--FGLGTADNPIFERMHEAAALITGGTIEAARAVWSGPPRHAVSIAGGLHHAMP 157
Query: 625 SEASGFCYVNDIVLGILELLKY-HQRVLYIDIDVHHGDGVEXAFYTTDRVMT 777
ASGFC ND + I LL RV Y+D+DVHHGDGV+ AFY RV+T
Sbjct: 158 GMASGFCIYNDPAIAIAWLLSAGAARVAYVDVDVHHGDGVQTAFYDDPRVLT 209
>UniRef50_Q6CVU3 Cluster: Similar to sp|Q12214 Saccharomyces
cerevisiae YPR068c HOS1; n=1; Kluyveromyces lactis|Rep:
Similar to sp|Q12214 Saccharomyces cerevisiae YPR068c
HOS1 - Kluyveromyces lactis (Yeast) (Candida sphaerica)
Length = 441
Score = 102 bits (245), Expect = 9e-21
Identities = 53/116 (45%), Positives = 71/116 (61%), Gaps = 2/116 (1%)
Frame = +1
Query: 436 DNVSEYN-KQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAAVKLNKQASEICINWGGGLH 612
D+VS+ + K ++ + DCP F L + Q+ GG+++ ++ Q I INW GG H
Sbjct: 134 DDVSKLDDKDFTKYGLQHDCPKFPFLSMYLQVIVGGTLSLLQHIDHQTPSIAINWDGGRH 193
Query: 613 HAKKSEASGFCYVNDIVLGILEL-LKYHQRVLYIDIDVHHGDGVEXAFYTTDRVMT 777
HA K ASGFCYVNDIVL I L K +RV YID D+H+GDGV AF ++ V T
Sbjct: 194 HALKHYASGFCYVNDIVLLIQSLRRKGWKRVTYIDFDLHYGDGVAKAFRFSENVQT 249
>UniRef50_Q6FWB7 Cluster: Similar to sp|Q12214 Saccharomyces
cerevisiae YPR068c HOS1; n=1; Candida glabrata|Rep:
Similar to sp|Q12214 Saccharomyces cerevisiae YPR068c
HOS1 - Candida glabrata (Yeast) (Torulopsis glabrata)
Length = 445
Score = 101 bits (243), Expect = 2e-20
Identities = 47/107 (43%), Positives = 71/107 (66%), Gaps = 2/107 (1%)
Frame = +1
Query: 463 MQRFNVGEDCPVFDGLYEFCQLSAGGSVAAAVKLNKQASE-ICINWGGGLHHAKKSEASG 639
+ +FN+ +DCP+F L +C +S G +++ A + + + I INW GG HH+ K++ASG
Sbjct: 153 LAKFNLLDDCPIFPYLPLYCYVSTGATLSLAQYILEGSERTIAINWDGGRHHSMKTKASG 212
Query: 640 FCYVNDIVLGILELLKYH-QRVLYIDIDVHHGDGVEXAFYTTDRVMT 777
FCY+NDI L I+ L + R+ Y+D D+HHGDGVE AF + +V T
Sbjct: 213 FCYINDIALLIMTLRRGGVDRISYVDFDLHHGDGVEKAFKYSKQVQT 259
>UniRef50_Q59Q78 Cluster: Likely histone deacetylase Hos1p; n=2;
Saccharomycetales|Rep: Likely histone deacetylase Hos1p
- Candida albicans (Yeast)
Length = 436
Score = 101 bits (241), Expect = 3e-20
Identities = 53/117 (45%), Positives = 70/117 (59%), Gaps = 5/117 (4%)
Frame = +1
Query: 442 VSEYNKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAAVKLNKQASE-----ICINWGGG 606
V E N +++ + DC F L + QL+A S+ AA K+ +Q E I +NW GG
Sbjct: 140 VIEENDLDEKYGLTFDCYPFPSLDLYVQLTAASSINAARKIVQQVKETKDQIIAVNWYGG 199
Query: 607 LHHAKKSEASGFCYVNDIVLGILELLKYHQRVLYIDIDVHHGDGVEXAFYTTDRVMT 777
HH KS A+GFCYVND+VL I L K V Y+D+D+HHGDGVE AF + +V T
Sbjct: 200 RHHCHKSHAAGFCYVNDVVLSINILRKNLGSVFYLDLDLHHGDGVENAFKFSKKVAT 256
>UniRef50_Q75BA6 Cluster: ADL339Wp; n=1; Eremothecium gossypii|Rep:
ADL339Wp - Ashbya gossypii (Yeast) (Eremothecium
gossypii)
Length = 437
Score = 100 bits (240), Expect = 4e-20
Identities = 49/107 (45%), Positives = 68/107 (63%), Gaps = 2/107 (1%)
Frame = +1
Query: 463 MQRFNVGEDCPVFDGLYEFCQLSAGGSVAAAVKLNK-QASEICINWGGGLHHAKKSEASG 639
+ ++ + +DCPV D L + AG ++A A +L++ + S + +NW GG HHA K+ ASG
Sbjct: 143 LAKYGLHDDCPVMDYLPMYIHTVAGATLALAKELSRHRGSALAVNWDGGRHHALKARASG 202
Query: 640 FCYVNDIVLGILELLKY-HQRVLYIDIDVHHGDGVEXAFYTTDRVMT 777
FCYVNDI L I L + RV Y+D D+HHGDGVE AF + V T
Sbjct: 203 FCYVNDIALLIQTLRRQGFLRVSYVDFDLHHGDGVENAFRYSKNVQT 249
>UniRef50_Q2S035 Cluster: Acetoin utilization protein acuC; n=4;
Bacteria|Rep: Acetoin utilization protein acuC -
Salinibacter ruber (strain DSM 13855)
Length = 378
Score = 91.1 bits (216), Expect = 3e-17
Identities = 51/157 (32%), Positives = 80/157 (50%)
Frame = +1
Query: 274 HPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVSEY 453
HP P R MT +LL G + P AT +E+ + H + ++ + + D
Sbjct: 19 HPFSPVRQEMTMDLLAALGA--PLNPVAPSVATREEVRRVHGEQFVEKVEAAS-DGTPPP 75
Query: 454 NKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAAVKLNKQASEICINWGGGLHHAKKSEA 633
+ + G D PVF+ + + GG++ A + + + +GGGLHHA ++ A
Sbjct: 76 EARAFGLDTG-DVPVFENMDAAARGLVGGTLHGARLIGDGDATRVLQFGGGLHHAHRARA 134
Query: 634 SGFCYVNDIVLGILELLKYHQRVLYIDIDVHHGDGVE 744
SGFC ND+ + I L + RV Y+D+DVHHGDGV+
Sbjct: 135 SGFCVYNDLSVAIHALREQGLRVAYVDVDVHHGDGVQ 171
>UniRef50_Q981B8 Cluster: Acetylpolyamine aminohydrolase; n=4;
Sulfolobaceae|Rep: Acetylpolyamine aminohydrolase -
Sulfolobus solfataricus
Length = 351
Score = 91.1 bits (216), Expect = 3e-17
Identities = 52/167 (31%), Positives = 75/167 (44%)
Frame = +1
Query: 274 HPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVSEY 453
HP K R MT LL G + + + P + + HS +YI F V
Sbjct: 21 HPFKSLRESMTKRLLEERGAFHFITLVEPKSIPEEALQLVHSKEYIEF--------VKYK 72
Query: 454 NKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAAVKLNKQASEICINWGGGLHHAKKSEA 633
+K+ Q + D P F G+YE + GSV A + IN GGG HHAK++ A
Sbjct: 73 SKEGQGYLDDGDTPAFKGIYEAALIRVSGSVKALELIKSGEFNHTINIGGGFHHAKRNRA 132
Query: 634 SGFCYVNDIVLGILELLKYHQRVLYIDIDVHHGDGVEXAFYTTDRVM 774
+GFC ND+ L + R+ +DID HH DG + + ++
Sbjct: 133 AGFCVFNDVALISKLGESFFSRIAIVDIDGHHADGTQELLIDDNNIL 179
>UniRef50_Q381M6 Cluster: Histone deacetylase 2; n=4;
Trypanosoma|Rep: Histone deacetylase 2 - Trypanosoma
brucei
Length = 566
Score = 90.2 bits (214), Expect = 5e-17
Identities = 45/108 (41%), Positives = 64/108 (59%), Gaps = 4/108 (3%)
Frame = +1
Query: 466 QRFNVGEDCPVFDGLYEFCQLSAGGSVAAAVKLNKQASEICINWGGGLHHAKKSEASGFC 645
+RFN+ D F G++ F Q G++AA L + + I+W GG H+AK++ A G C
Sbjct: 141 KRFNLVGDSAPFSGMWRFTQAVVSGTLAATRLLAQPSRFAAIHWMGGKHNAKRASAGGSC 200
Query: 646 YVNDIVLGILELLKY----HQRVLYIDIDVHHGDGVEXAFYTTDRVMT 777
VND+VL +LEL K VL +D+D HHGDG + AF + RV+T
Sbjct: 201 LVNDVVLAVLELRKLLPANRNVVLAVDLDAHHGDGAQEAFLSDPRVVT 248
>UniRef50_O30107 Cluster: Uncharacterized protein AF_0130; n=2;
Euryarchaeota|Rep: Uncharacterized protein AF_0130 -
Archaeoglobus fulgidus
Length = 359
Score = 86.2 bits (204), Expect = 8e-16
Identities = 52/171 (30%), Positives = 91/171 (53%), Gaps = 4/171 (2%)
Frame = +1
Query: 274 HPMKPHRIRMTHNLLLNYGLYR--KMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVS 447
HP + R+ T + L G++ ++ + P KA+ +++ + H+++Y+RFL
Sbjct: 20 HPERRERLAYTMDQLREEGIFESERIVLLEPFKASLEDVLEVHTEEYVRFLEM------- 72
Query: 448 EYNKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAA-VKLNKQASEICINWGGGLHHAKK 624
+K+ + + PV G+++ L+AGG++ AA LNK+ HHAK
Sbjct: 73 -ESKKGGIIDFDTNIPV--GVFDRALLAAGGAIRAAQAVLNKECENAFAMIRPPGHHAKP 129
Query: 625 SEASGFCYVNDIVLGILELLKY-HQRVLYIDIDVHHGDGVEXAFYTTDRVM 774
+GFCY+N++ + + LLK +R+ +D D HHGDG + FY DRV+
Sbjct: 130 YIGAGFCYLNNMAIMVKWLLKQGFERIAILDWDAHHGDGTQEIFYNDDRVL 180
>UniRef50_A5E4H2 Cluster: Putative uncharacterized protein; n=1;
Lodderomyces elongisporus NRRL YB-4239|Rep: Putative
uncharacterized protein - Lodderomyces elongisporus
(Yeast) (Saccharomyces elongisporus)
Length = 410
Score = 82.6 bits (195), Expect = 1e-14
Identities = 43/116 (37%), Positives = 65/116 (56%), Gaps = 12/116 (10%)
Frame = +1
Query: 466 QRFNVGEDCPVFDGLYEFCQLSAGGSVAAAVKL-----NKQASE------ICINWGGGLH 612
+ + + DC VF + + L+A ++ A + N + S+ I INW GG H
Sbjct: 116 ENYGLTHDCYVFPFMRHYVALTAASTIELATHIARMVVNSRDSDDLHIRPIGINWYGGRH 175
Query: 613 HAKKSEASGFCYVNDIVLGILELLKY-HQRVLYIDIDVHHGDGVEXAFYTTDRVMT 777
H +++ SGFCY+ND+VLGI L K V Y+D+D+HHGDG+ AF + +V T
Sbjct: 176 HCHRAKCSGFCYINDVVLGINALRKLTSATVFYLDLDLHHGDGISQAFQYSKKVTT 231
>UniRef50_A0L9T2 Cluster: Histone deacetylase superfamily; n=3;
Proteobacteria|Rep: Histone deacetylase superfamily -
Magnetococcus sp. (strain MC-1)
Length = 327
Score = 81.0 bits (191), Expect = 3e-14
Identities = 52/163 (31%), Positives = 74/163 (45%), Gaps = 2/163 (1%)
Frame = +1
Query: 271 GHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVSE 450
GHP R+ L K+ I P A +++ FH+ Y+ ++ R + E
Sbjct: 26 GHPWTTTRMDAFWQEATRQSLSSKVVIADPVMAQPEQLHSFHTPQYVELVK--RCSDAGE 83
Query: 451 YNKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAAVKLNKQASEICINWGGGLHHAKKSE 630
F D P F G+YE G +VAAA ++ +Q GLHHA+
Sbjct: 84 ------GFLDHGDTPAFPGIYEAAAYVVGSAVAAAEQIMQQRFRRIFIPIAGLHHAQPDV 137
Query: 631 ASGFCYVNDIVLGILELLKYH--QRVLYIDIDVHHGDGVEXAF 753
A GFC ND + + L K H +++ Y+DID HHGDGV F
Sbjct: 138 AGGFCVFNDAAVVVKHLRKQHGIKKIAYVDIDAHHGDGVFYPF 180
>UniRef50_Q7VZF1 Cluster: Histone deacetylase family protein; n=6;
Proteobacteria|Rep: Histone deacetylase family protein -
Bordetella pertussis
Length = 307
Score = 76.6 bits (180), Expect = 7e-13
Identities = 51/171 (29%), Positives = 84/171 (49%), Gaps = 4/171 (2%)
Frame = +1
Query: 274 HPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVSEY 453
HP P R+ + LL GL ++ + +A+ ++ + H+ Y+ LR+ +P++
Sbjct: 20 HPESPQRLDAISDQLLASGLLPYLQERQAPEASRADILRVHTPAYLDSLRAHQPEH---- 75
Query: 454 NKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAA--AVKLNKQASEICINWGGGLHHAKKS 627
+ + D + YE +AG VAA AV + + C G HHA++
Sbjct: 76 ----GYYAIDADTSMNRHTYEAALRAAGAGVAAVDAVLGGEAITAFCSVRPPG-HHAERD 130
Query: 628 EASGFCYVNDIVLGILELLKYH--QRVLYIDIDVHHGDGVEXAFYTTDRVM 774
A GFC++N++ + L +H QRV +D DVHHG+G E AF RV+
Sbjct: 131 HAMGFCFLNNVAIAARHALDFHGLQRVALVDFDVHHGNGTEHAFAGDPRVL 181
>UniRef50_Q64AZ9 Cluster: Deacetylase; n=1; uncultured archaeon
GZfos28B8|Rep: Deacetylase - uncultured archaeon
GZfos28B8
Length = 361
Score = 76.6 bits (180), Expect = 7e-13
Identities = 51/174 (29%), Positives = 83/174 (47%), Gaps = 6/174 (3%)
Frame = +1
Query: 271 GHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSI-RPDNVS 447
GHP++ R M H L+ + +I KA +++ +YI F R+ + N+
Sbjct: 21 GHPIRGERYLMFHRFLMENVSEQIYQIIGTEKANDEDLLFICEKEYIDFTRAYYKAANLG 80
Query: 448 -EYNKQMQRFNVGEDCPVFDG--LYEFCQLSAGGSVAAAVKLNKQASEICINWGGGLHHA 618
+Y+ + F+ ++ PV + E +L G + A + E ++ GGGLHHA
Sbjct: 81 FDYDGRFYLFHSADNRPVGKPGKVEEAARLIIGQAKRAVDLVESGEFEKAVSIGGGLHHA 140
Query: 619 KKSEASGFCYVNDIVLGILELLKYH--QRVLYIDIDVHHGDGVEXAFYTTDRVM 774
K S GFC ND+ L++ + +R+L +D D H G+G FY RVM
Sbjct: 141 KPSFGEGFCLYNDVAYTAKYLMQEYDLKRILILDTDAHAGNGTSEYFYQDPRVM 194
>UniRef50_Q0LS19 Cluster: Histone deacetylase superfamily; n=1;
Caulobacter sp. K31|Rep: Histone deacetylase superfamily
- Caulobacter sp. K31
Length = 379
Score = 76.2 bits (179), Expect = 9e-13
Identities = 50/172 (29%), Positives = 82/172 (47%), Gaps = 4/172 (2%)
Frame = +1
Query: 274 HPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVSEY 453
H P +R NL+ GL +K+ AT E+ + H+ D+I ++ +
Sbjct: 36 HVYDPEVVRRFRNLVDVSGLLKKLVDIPARLATGLEIGRVHTSDHINQIKIMSGFPTGG- 94
Query: 454 NKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAA--AVKLNKQASEICINWGGGLHHAKKS 627
G+D PV G +E L+AGG++AA AV + + + G HH++
Sbjct: 95 -------EPGDDAPVPYGAFEIASLAAGGAIAAVDAVMSGEVDNAYALLRPAG-HHSRPD 146
Query: 628 EASGFCYVNDIVLGILELLKYH--QRVLYIDIDVHHGDGVEXAFYTTDRVMT 777
+ GFC ++ + LL +H +R+ Y+D DVHHG+G + A Y R +T
Sbjct: 147 RSMGFCIFSNAAIAGRHLLDFHNVKRIAYVDWDVHHGNGTQAALYNEPRALT 198
>UniRef50_Q1H193 Cluster: Histone deacetylase superfamily; n=2;
Betaproteobacteria|Rep: Histone deacetylase superfamily
- Methylobacillus flagellatus (strain KT / ATCC 51484 /
DSM 6875)
Length = 307
Score = 75.8 bits (178), Expect = 1e-12
Identities = 56/173 (32%), Positives = 81/173 (46%), Gaps = 6/173 (3%)
Frame = +1
Query: 274 HPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVSEY 453
HP P RI + L + L K++ + +AT + + + H YI+ +RSI P
Sbjct: 20 HPESPARITAIMDALAEHRLLDKLQRHEAPQATDEALLRVHDAAYIKHIRSIAP------ 73
Query: 454 NKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAAVKL--NKQASEI--CINWGGGLHHAK 621
+ + D + C L A G+V AV L KQ + C+ G HHA
Sbjct: 74 --RAGIVRLDPDTAMGPMSLSAC-LHASGAVIKAVDLVMQKQVTNAFCCVRPPG--HHAG 128
Query: 622 KSEASGFCYVNDIVLGILELLKYHQ--RVLYIDIDVHHGDGVEXAFYTTDRVM 774
++ A+GFC N I G+ L ++ R+ +DIDVHHGDG E F RVM
Sbjct: 129 RARAAGFCIFNHIAAGVAYALASYKLKRIAVLDIDVHHGDGTEDIFRNDPRVM 181
>UniRef50_O88895-2 Cluster: Isoform Short of O88895 ; n=6;
Euteleostomi|Rep: Isoform Short of O88895 - Mus musculus
(Mouse)
Length = 233
Score = 75.4 bits (177), Expect = 2e-12
Identities = 27/47 (57%), Positives = 42/47 (89%)
Frame = +1
Query: 271 GHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYI 411
GHPMKPHR+ +TH+L+L+YGLY+KM +++P++A+ +M +FHS+DYI
Sbjct: 21 GHPMKPHRLALTHSLVLHYGLYKKMIVFKPYQASQHDMCRFHSEDYI 67
>UniRef50_Q28M71 Cluster: Histone deacetylase superfamily; n=15;
Alphaproteobacteria|Rep: Histone deacetylase superfamily
- Jannaschia sp. (strain CCS1)
Length = 375
Score = 74.9 bits (176), Expect = 2e-12
Identities = 50/162 (30%), Positives = 77/162 (47%), Gaps = 2/162 (1%)
Frame = +1
Query: 274 HPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVSEY 453
HP++ R+ +L G + +A + +H+ YI L+ D
Sbjct: 20 HPLRVPRVSTVMDLSRAMGWLGPGQYRNSPRAKPAALHVWHTPAYIAALQQAEADQAVT- 78
Query: 454 NKQMQRFNVGE-DCPVFDGLYEFCQLSAGGSVAAAVKLNKQASEICINWGGGLHHAKKSE 630
+ R +G P++ ++ +AG S+ A +L K I + GGG HH +
Sbjct: 79 DAVRDRHGLGTVSNPIYPEMFRRPATAAGASLLAG-ELLKDGGVI-YHPGGGTHHGMRDR 136
Query: 631 ASGFCYVNDIVLGILELLKY-HQRVLYIDIDVHHGDGVEXAF 753
A GFCY+ND VL +L L + +R+ Y+DID HH DGVE AF
Sbjct: 137 AGGFCYLNDPVLAMLSLRRNGARRIAYVDIDAHHCDGVEDAF 178
>UniRef50_UPI0000DB73BE Cluster: PREDICTED: similar to HDAC6
CG6170-PA, isoform A; n=2; Apis mellifera|Rep:
PREDICTED: similar to HDAC6 CG6170-PA, isoform A - Apis
mellifera
Length = 1019
Score = 74.5 bits (175), Expect = 3e-12
Identities = 47/171 (27%), Positives = 80/171 (46%), Gaps = 4/171 (2%)
Frame = +1
Query: 274 HPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVSEY 453
HP KPHRI + + Y L + + + AT +E+ H+ +YI +++ + E
Sbjct: 485 HPEKPHRINIIYKKFQEYNLLDRSFVQQGRSATKEELLLVHTKEYIDKIKNTKNLKSKEL 544
Query: 454 NKQMQRFNVGEDCPVFDGLYEFCQLSAGG--SVAAAVKLNKQASEICINWGGGLHHAKKS 627
KQ + +N + + +S G V V + S I I G HHA +
Sbjct: 545 KKQAETYN---SVYLHPETWSSACISTGSLLQVVDNVLNGESQSGIAIIRPPG-HHATED 600
Query: 628 EASGFCYVNDIVLGILELLKYH--QRVLYIDIDVHHGDGVEXAFYTTDRVM 774
A GFC N++ + +++H +RVL +D DVH+G+G + F +V+
Sbjct: 601 AACGFCIFNNVAIAAKYAIEFHHVKRVLIVDWDVHYGNGTQSIFEEDSKVL 651
Score = 56.8 bits (131), Expect = 6e-07
Identities = 42/172 (24%), Positives = 74/172 (43%), Gaps = 5/172 (2%)
Frame = +1
Query: 274 HPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVSEY 453
+P P R+ GL + ++ P A+ +E+ HS + I L+S D ++
Sbjct: 105 YPECPARLIRVLQRCEELGLISRCKLITPRLASENEILIKHSQEQIDILKST--DGCTDI 162
Query: 454 NKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAAVKLNK---QASEICINWGGGLHHAKK 624
N + + + Y L+ G ++ + K Q I G HHA K
Sbjct: 163 NNLELLSSKYDAIYIHPSTYRLSLLAVGSTINLVESICKGEIQNGMAIIRPPG--HHAMK 220
Query: 625 SEASGFCYVNDIVLGILELL--KYHQRVLYIDIDVHHGDGVEXAFYTTDRVM 774
SE G+C+ N++ + ++L ++L +D DVHHG + FY +V+
Sbjct: 221 SEYCGYCFFNNVAIAAEKVLCNNLASKILIVDWDVHHGQATQQMFYDNPQVI 272
>UniRef50_A5D0K9 Cluster: Deacetylases; n=1; Pelotomaculum
thermopropionicum SI|Rep: Deacetylases - Pelotomaculum
thermopropionicum SI
Length = 355
Score = 73.7 bits (173), Expect = 5e-12
Identities = 51/172 (29%), Positives = 85/172 (49%), Gaps = 4/172 (2%)
Frame = +1
Query: 271 GHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVSE 450
G P P R++ T+ +L G+ K+ +P AT +E++ H YI + V E
Sbjct: 26 GCPESPARVKHTYEILKIAGMLEKLVTIKPRPATVEEVSLVHLPAYI--------ERVKE 77
Query: 451 YNKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAA--AVKLNKQASEICINWGGGLHHAKK 624
++K+ + G + +E L+AGG+++A AV + S + G HHA+
Sbjct: 78 FSKRGGG-SFGNNTTGSPETFETALLAAGGTLSAVEAVLEGRVESAFALVRPPG-HHARP 135
Query: 625 SEASGFCYVNDIVLGILELLKYH--QRVLYIDIDVHHGDGVEXAFYTTDRVM 774
+A G+C+ N+ + +K + RVL ID D HHG+G E FY+ V+
Sbjct: 136 GQAMGYCFFNNAAIAARYAIKRYGLSRVLIIDWDEHHGNGTEEIFYSDPSVL 187
>UniRef50_Q8IR37 Cluster: CG6170-PC, isoform C; n=7; Diptera|Rep:
CG6170-PC, isoform C - Drosophila melanogaster (Fruit
fly)
Length = 1138
Score = 73.3 bits (172), Expect = 6e-12
Identities = 48/172 (27%), Positives = 84/172 (48%), Gaps = 4/172 (2%)
Frame = +1
Query: 271 GHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVSE 450
GHP +P RI+ H + +YGL ++M+ P AT DE+ H+ ++ +R + E
Sbjct: 562 GHPEQPSRIQHIHKMHDDYGLLKQMKQLSPRAATTDEVCLAHTRAHVNTVRRLLGREPKE 621
Query: 451 YNKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAA--AVKLNKQASEICINWGGGLHHAKK 624
+ +N + ++ L+AG + A +V + S IC N HHA++
Sbjct: 622 LHDAAGIYN---SVYLHPRTFDCATLAAGLVLQAVDSVLRGESRSGIC-NVRPPGHHAEQ 677
Query: 625 SEASGFCYVNDIVLGILELLKYH--QRVLYIDIDVHHGDGVEXAFYTTDRVM 774
GFC N++ + ++ +RVL +D DVHHG+G + F + +V+
Sbjct: 678 DHPHGFCIFNNVAIAAQYAIRDFGLERVLIVDWDVHHGNGTQHIFESNPKVL 729
Score = 66.1 bits (154), Expect = 9e-10
Identities = 39/140 (27%), Positives = 69/140 (49%), Gaps = 4/140 (2%)
Frame = +1
Query: 367 ATADEMTKFHSDDYIRFLRSIRPDNVSEYNKQMQRFNVGEDCPVFDGLYEFCQLSAGGSV 546
AT DE+ + H++++ L+ + + + + + + + +E L++G ++
Sbjct: 166 ATKDEILRLHTEEHFERLKET--SGIRDDERMEELSSRYDSIYIHPSTFELSLLASGSTI 223
Query: 547 AAAVKL--NKQASEICINWGGGLHHAKKSEASGFCYVNDIVLGILELLKYH--QRVLYID 714
L K + + I G HHA K+E +G+C+ N++ L L H QR+L ID
Sbjct: 224 ELVDHLVAGKAQNGMAIIRPPG-HHAMKAEYNGYCFFNNVALATQHALDVHKLQRILIID 282
Query: 715 IDVHHGDGVEXAFYTTDRVM 774
DVHHG G + FY RV+
Sbjct: 283 YDVHHGQGTQRFFYNDPRVV 302
>UniRef50_Q17MD0 Cluster: Histone deacetylase; n=1; Aedes
aegypti|Rep: Histone deacetylase - Aedes aegypti
(Yellowfever mosquito)
Length = 1059
Score = 73.3 bits (172), Expect = 6e-12
Identities = 54/174 (31%), Positives = 82/174 (47%), Gaps = 5/174 (2%)
Frame = +1
Query: 268 QGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVS 447
+ HP +P R+ + Y L +M+ +P AT E+ HS ++ +R R
Sbjct: 479 EDHPEQPDRVAKIYTRHEEYKLLARMKRLKPRHATTTELCMVHSRQHVNVIR--RTVERE 536
Query: 448 EYNKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAAVK--LNKQA-SEICINWGGGLHHA 618
E + +FN P +E C A GSV V LN Q+ S +CI G HHA
Sbjct: 537 EMKQVADQFNSVYFHPK---TFE-CATLAAGSVLQVVDEVLNGQSRSGVCIVRPPG-HHA 591
Query: 619 KKSEASGFCYVNDIVLGILELLKYH--QRVLYIDIDVHHGDGVEXAFYTTDRVM 774
+ GFC N++ + ++ H +RVL +D DVHHG+G + F + RV+
Sbjct: 592 ESDMPHGFCIFNNVAIAAQYAIRDHGLKRVLIVDWDVHHGNGTQHIFESDPRVL 645
Score = 64.9 bits (151), Expect = 2e-09
Identities = 49/176 (27%), Positives = 80/176 (45%), Gaps = 7/176 (3%)
Frame = +1
Query: 268 QGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVS 447
+G+P P R GL + ++ P AT +E+ H+ + + LR + S
Sbjct: 50 EGYPECPERFTRVLERCRELGLVDRCKMIEPRMATEEEILTKHTPEQVEILRGTKG---S 106
Query: 448 EYNKQMQRFNVGEDCP-VFDGLYEFCQLSAGGS----VAAAVKLNKQASEICINWGGGLH 612
E ++++ + D V Y+ C L A GS V A V Q I G H
Sbjct: 107 EDLERLEELSSHYDAVFVHPSSYD-CSLLACGSTIELVDAVVGGRVQNGMAIIRPPG--H 163
Query: 613 HAKKSEASGFCYVNDIVLGILELLKYH--QRVLYIDIDVHHGDGVEXAFYTTDRVM 774
HA K+E +G+C+ N++ + L +++L +D D+HHG G + FY RV+
Sbjct: 164 HAMKAEYNGYCFFNNVAIAAQHALDRLGLKKILVVDWDIHHGQGTQRMFYDDPRVL 219
>UniRef50_Q7NRU4 Cluster: Histone deacetylase; n=54;
Proteobacteria|Rep: Histone deacetylase -
Chromobacterium violaceum
Length = 319
Score = 72.9 bits (171), Expect = 8e-12
Identities = 43/172 (25%), Positives = 81/172 (47%), Gaps = 4/172 (2%)
Frame = +1
Query: 271 GHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVSE 450
GHP P R+ + L+ ++ ++ + + +++ + H Y+ +L + P
Sbjct: 31 GHPECPERLTAIRDQLMASQIFDSLQEIEAPEVSYEQLARVHPPRYVEYLEACAPS---- 86
Query: 451 YNKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAA--VKLNKQASEICINWGGGLHHAKK 624
+ F + D + G + + +AG V A V +K + C G HHA+
Sbjct: 87 ----VGTFRMDPDTAMSPGTLKAARRAAGAVVKAVELVAEDKAPNAFCAIRPPG-HHAES 141
Query: 625 SEASGFCYVNDIVLGILELLKYH--QRVLYIDIDVHHGDGVEXAFYTTDRVM 774
+A GFC+ N++ +G+ L ++ +RV +D DVHHG+G E + RV+
Sbjct: 142 DKAMGFCFFNNLAVGVTHALAHYKFERVAVVDFDVHHGNGTEEILHDDPRVL 193
>UniRef50_A3JCC1 Cluster: Deacetylases, including yeast histone
deacetylase and acetoin utilization protein; n=2;
Gammaproteobacteria|Rep: Deacetylases, including yeast
histone deacetylase and acetoin utilization protein -
Marinobacter sp. ELB17
Length = 308
Score = 72.9 bits (171), Expect = 8e-12
Identities = 44/172 (25%), Positives = 83/172 (48%), Gaps = 5/172 (2%)
Frame = +1
Query: 274 HPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVSEY 453
HP +P R+ + L + L + ++ RP + T D++ H + Y++ L ++P
Sbjct: 20 HPERPERMAAIQSYLADTALNQDLDYVRPDEITRDQLLIVHPESYLKQLDMMQPTR---- 75
Query: 454 NKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAA-VKLNKQASE--ICINWGGGLHHAKK 624
R D + +L+AG ++ A + ++ Q + +C G HHA++
Sbjct: 76 ----GRVFTDPDTAMMPDTLRAARLAAGANIQAVDMVMSSQVTNAFVCARPPG--HHAER 129
Query: 625 SEASGFCYVNDIVLGILELLKYH--QRVLYIDIDVHHGDGVEXAFYTTDRVM 774
S++ GFC+ N++ L + L +H +RV ID DVH G+G +R++
Sbjct: 130 SKSMGFCFYNNVALAAMRALSFHRLERVAIIDFDVHQGNGTVDIVGGDERIL 181
>UniRef50_A1RXP5 Cluster: Histone deacetylase superfamily; n=1;
Thermofilum pendens Hrk 5|Rep: Histone deacetylase
superfamily - Thermofilum pendens (strain Hrk 5)
Length = 360
Score = 72.5 bits (170), Expect = 1e-11
Identities = 36/108 (33%), Positives = 55/108 (50%), Gaps = 5/108 (4%)
Frame = +1
Query: 448 EYNKQMQRFNVG----EDCPVFDGLYEFCQLSAGGSVAAAVKLNKQASEICINWGGGLHH 615
+Y K+M G D P + G++E L+ G++ A L K + N GG HH
Sbjct: 75 DYVKRMSELGAGLLDYGDTPAYPGVFEKALLAVSGTLTLADILVKAGRGVAFNPQGGFHH 134
Query: 616 AKKSEASGFCYVNDIVLGILELL-KYHQRVLYIDIDVHHGDGVEXAFY 756
A++ A GFC ND+ + + + ++RV ID+D HHGDG + Y
Sbjct: 135 ARRRSAGGFCVFNDVAVAARYVRERGYERVAIIDVDAHHGDGTQEILY 182
>UniRef50_Q803K0 Cluster: Zgc:55652; n=4; Danio rerio|Rep: Zgc:55652
- Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 676
Score = 71.7 bits (168), Expect = 2e-11
Identities = 43/161 (26%), Positives = 80/161 (49%), Gaps = 5/161 (3%)
Frame = +1
Query: 286 PHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVSEYNKQM 465
P R+ +++ L +GL ++ + +AT E+ HS++Y+ ++ NV E
Sbjct: 30 PERLTVSYEALRTHGLAQRCKAVPVRQATEQEILLAHSEEYLEAVKQTPGMNVEELMAFS 89
Query: 466 QRFNVGEDCPVFDGLYEFCQLSAGGS---VAAAVKLNKQASEICINWGGGLHHAKKSEAS 636
+++N D +Y +L+AG + V + +K + + G HH+++S A+
Sbjct: 90 KKYN---DVYFHQNIYHCAKLAAGATLQLVDSVMKREVRNGMALVRPPG--HHSQRSAAN 144
Query: 637 GFCYVNDIVLGILELLKYH--QRVLYIDIDVHHGDGVEXAF 753
GFC N++ L K + R+L +D DVHHG G++ F
Sbjct: 145 GFCVFNNVAFAALYAKKNYNLNRILIVDWDVHHGQGIQYCF 185
>UniRef50_Q5K8L3 Cluster: Histone deacetylase 3, putative; n=2;
Filobasidiella neoformans|Rep: Histone deacetylase 3,
putative - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 555
Score = 70.9 bits (166), Expect = 3e-11
Identities = 42/115 (36%), Positives = 59/115 (51%), Gaps = 19/115 (16%)
Frame = +1
Query: 472 FNVGEDCPVFDGLYEFCQLSAGGSVAAAVKLNKQASEICINWGGGLHHAKKSEASGFCYV 651
+N+ D PVF L + + A L ++ + W GG HHAK+ EA GFCYV
Sbjct: 225 YNLSHDNPVFPTLASYISHVTAATSTACRLLATDKADWAVCWDGGRHHAKRKEAGGFCYV 284
Query: 652 NDIVLGILEL---------LKYHQ----------RVLYIDIDVHHGDGVEXAFYT 759
ND+VLG L L LK + R+LY+D+D+H+ DGV AF++
Sbjct: 285 NDLVLGGLLLSREGRIPLPLKEGEDPKRQRTRAPRILYLDMDLHYSDGVSAAFHS 339
>UniRef50_Q97Z24 Cluster: Acetoin utilization protein; n=3;
Sulfolobaceae|Rep: Acetoin utilization protein -
Sulfolobus solfataricus
Length = 348
Score = 70.9 bits (166), Expect = 3e-11
Identities = 44/134 (32%), Positives = 68/134 (50%)
Frame = +1
Query: 355 RPHKATADEMTKFHSDDYIRFLRSIRPDNVSEYNKQMQRFNVGEDCPVFDGLYEFCQLSA 534
RP AT +++ H+ DYI L S + + G D + G++E L
Sbjct: 55 RPEYATKEDLMVVHTRDYIGLLEE------SSKIPYIGFLDQG-DTVHYPGMFEDILLVL 107
Query: 535 GGSVAAAVKLNKQASEICINWGGGLHHAKKSEASGFCYVNDIVLGILELLKYHQRVLYID 714
G S A +K +K + I GG HHA + A GFC +ND+ + L+LL+ +RV +D
Sbjct: 108 GSSFTA-IKYSKFLDYVYIPLGG-FHHAMPNRAVGFCPINDVAITALKLLEKGERVAIVD 165
Query: 715 IDVHHGDGVEXAFY 756
+D HHG+G++ Y
Sbjct: 166 VDAHHGNGLQFILY 179
>UniRef50_Q57ET7 Cluster: Histone deacetylase family protein; n=33;
Bacteria|Rep: Histone deacetylase family protein -
Brucella abortus
Length = 337
Score = 70.1 bits (164), Expect = 6e-11
Identities = 49/172 (28%), Positives = 79/172 (45%), Gaps = 4/172 (2%)
Frame = +1
Query: 271 GHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVSE 450
GHP +P RIR + L YR + PH A + H ++++ +RS P+ V +
Sbjct: 40 GHPERPDRIRALMSELEGPDFYRLDRVEAPHAGEAAILLA-HPEEHLEAVRSKIPEPVED 98
Query: 451 YNKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAAVK--LNKQASEICINWGGGLHHAKK 624
+ D V + L+A G+ AAV ++ A + + HHA++
Sbjct: 99 GEASQPIVKLDGDTYVSPKSMD-AALTAIGAAMAAVDDVMSGAADNVFVASRPPGHHAER 157
Query: 625 SEASGFCYVNDIVLGILELLKYH--QRVLYIDIDVHHGDGVEXAFYTTDRVM 774
S A GFC N+I + ++H +R+ +D DVHHG+G + F VM
Sbjct: 158 SRAMGFCVFNNIAIAARHAQRHHGLERIAIVDGDVHHGNGTQDIFKDDPGVM 209
>UniRef50_Q02A43 Cluster: Histone deacetylase superfamily; n=1;
Solibacter usitatus Ellin6076|Rep: Histone deacetylase
superfamily - Solibacter usitatus (strain Ellin6076)
Length = 305
Score = 70.1 bits (164), Expect = 6e-11
Identities = 50/170 (29%), Positives = 75/170 (44%), Gaps = 2/170 (1%)
Frame = +1
Query: 274 HPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVSEY 453
H + R + LL+ + P AT D++ H +Y+ LR Y
Sbjct: 19 HVFPSQKFRWLRDRLLHTRFAAAEDFVTPESATDDDVRLVHDPEYVAKLRG----GTLSY 74
Query: 454 NKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAAVKLNKQASEICINWGGGLHHAKKSEA 633
+ + R + P + E L+AGGS+ AA +L Q I N GGG HHA
Sbjct: 75 -QDILRLEI----PYSRQMVEAFWLAAGGSILAA-RLALQDG-IGFNIGGGFHHAFPGHG 127
Query: 634 SGFCYVNDIVLGI--LELLKYHQRVLYIDIDVHHGDGVEXAFYTTDRVMT 777
GFC +ND+ + + L+ + +R + +D DVHHG+G F V T
Sbjct: 128 EGFCAINDVAIAVRRLQADRLIKRAMVVDCDVHHGNGTAAIFTDDQSVFT 177
>UniRef50_Q2S0V9 Cluster: Histone deacetylase/AcuC/AphA family
protein; n=2; Bacteria|Rep: Histone
deacetylase/AcuC/AphA family protein - Salinibacter
ruber (strain DSM 13855)
Length = 307
Score = 69.7 bits (163), Expect = 7e-11
Identities = 47/172 (27%), Positives = 78/172 (45%), Gaps = 2/172 (1%)
Frame = +1
Query: 268 QGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVS 447
+GHP + H LL+ L R ++ P +A ++ + H+ DY+ L ++S
Sbjct: 15 EGHPFPMAKFPALHQRLLDEDLIRPTDVVAPRQADWTDLRRVHTADYLTHLAE---GSLS 71
Query: 448 EYNKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAAVKLNKQASEICINWGGGLHHAKKS 627
++ ++ P + L +L+ G++ AA L + N GG HHA
Sbjct: 72 DHAERRMGL------PWSERLVYRSRLAVQGTINAA--LMALTDGVAANLAGGTHHAFPG 123
Query: 628 EASGFCYVNDIVLGI--LELLKYHQRVLYIDIDVHHGDGVEXAFYTTDRVMT 777
GFC +ND+ + I L+ + QRVL +D+DVH G+ F V T
Sbjct: 124 HGEGFCVLNDVAVAIRVLQAACWAQRVLIVDLDVHQGNANAAVFADDASVFT 175
>UniRef50_A6ND61 Cluster: Uncharacterized protein HDAC8; n=3;
Simiiformes|Rep: Uncharacterized protein HDAC8 - Homo
sapiens (Human)
Length = 139
Score = 68.9 bits (161), Expect = 1e-10
Identities = 31/61 (50%), Positives = 43/61 (70%), Gaps = 1/61 (1%)
Frame = +1
Query: 559 KLNKQASEI-CINWGGGLHHAKKSEASGFCYVNDIVLGILELLKYHQRVLYIDIDVHHGD 735
K+ K+AS + + LH + EASGFCY+ND VLGIL L + +R+LY+D+D+HHGD
Sbjct: 33 KIPKRASMVHSLIEAYALHKQMRDEASGFCYLNDAVLGILRLRRKFERILYVDLDLHHGD 92
Query: 736 G 738
G
Sbjct: 93 G 93
>UniRef50_Q569T0 Cluster: MGC115178 protein; n=5; Tetrapoda|Rep:
MGC115178 protein - Xenopus laevis (African clawed frog)
Length = 683
Score = 67.7 bits (158), Expect = 3e-10
Identities = 41/160 (25%), Positives = 81/160 (50%), Gaps = 4/160 (2%)
Frame = +1
Query: 286 PHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVSEYNKQM 465
P R+ ++ L +Y L ++ +AT +E+T HS DY++ ++S + N E +
Sbjct: 30 PERLSSSYKRLQDYDLVKRCIQLPVREATDEEITLVHSHDYLQVVKSTQTMNEKELKEIS 89
Query: 466 QRFNVGEDCPVFDGLYEFCQLSAGGS--VAAAVKLNKQASEICINWGGGLHHAKKSEASG 639
Q++ + +LS GG+ + A+ + + + I G HH+++++ +G
Sbjct: 90 QKYTA---VFYHQNSFRCAKLSLGGTLQLVDAILTREVQNGMAIVRPPG-HHSQRNQGNG 145
Query: 640 FCYVNDIVLGILELLKYH--QRVLYIDIDVHHGDGVEXAF 753
FC N++ + K + +R+L +D DVHHG G++ F
Sbjct: 146 FCVFNNVAIAAEYAKKKYKLERILIVDWDVHHGQGIQYIF 185
>UniRef50_A0IVC2 Cluster: Histone deacetylase superfamily; n=5;
Proteobacteria|Rep: Histone deacetylase superfamily -
Serratia proteamaculans 568
Length = 370
Score = 67.3 bits (157), Expect = 4e-10
Identities = 49/173 (28%), Positives = 84/173 (48%), Gaps = 4/173 (2%)
Frame = +1
Query: 271 GHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVSE 450
GH P R NL+ GL ++ + AT +++ + H +Y++ + + DN
Sbjct: 38 GHAESPETKRRMKNLMDVSGLSHQLSLLSAELATDEDLLRIHPANYLQRFKQLS-DNGGG 96
Query: 451 YNKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAA--AVKLNKQASEICINWGGGLHHAKK 624
+GE+ P+ G YE +LSAG + AA AV + + ++ G HH
Sbjct: 97 M--------LGEEAPLGPGSYEIAKLSAGLACAAVEAVLQGELENAYALSRPPG-HHCLP 147
Query: 625 SEASGFCYVNDIVLGILEL-LKYHQ-RVLYIDIDVHHGDGVEXAFYTTDRVMT 777
++ GFC++ +I + I KY +V +D DVHHG+G + ++ D V+T
Sbjct: 148 DQSMGFCFLANIPIAIERAKAKYGLGKVAVLDWDVHHGNGTQHIYWQRDDVLT 200
>UniRef50_Q9K0J2 Cluster: Histone deacetylase family protein; n=4;
Neisseria|Rep: Histone deacetylase family protein -
Neisseria meningitidis serogroup B
Length = 369
Score = 66.9 bits (156), Expect = 5e-10
Identities = 44/171 (25%), Positives = 77/171 (45%), Gaps = 4/171 (2%)
Frame = +1
Query: 274 HPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVSEY 453
HP P RI L G+++ ++ + + + HS Y+ L S P
Sbjct: 41 HPDSPDRILCIEQALRRAGIWQHLQTIEAEEISDTRLALVHSSKYLNRLESCLPQK---- 96
Query: 454 NKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAA-VKLNKQA-SEICINWGGGLHHAKKS 627
++ R + D + G + +AG +V A + +N++A C G HHA
Sbjct: 97 -GKISRLD--NDTAISTGSLSAARFAAGSAVQAVDMVMNRKAWHAFCAARPPG-HHAGSG 152
Query: 628 EASGFCYVNDIVLGILELLKYH--QRVLYIDIDVHHGDGVEXAFYTTDRVM 774
+A GFC +N++ G++ + + +R+ ID DVH+GDG F R++
Sbjct: 153 KAGGFCLLNNVAAGVMHAIAEYRLKRIAVIDFDVHYGDGTAEIFKDDPRIL 203
>UniRef50_Q2LVD3 Cluster: Histone deacetylase family protein; n=1;
Syntrophus aciditrophicus SB|Rep: Histone deacetylase
family protein - Syntrophus aciditrophicus (strain SB)
Length = 350
Score = 66.9 bits (156), Expect = 5e-10
Identities = 45/172 (26%), Positives = 79/172 (45%), Gaps = 4/172 (2%)
Frame = +1
Query: 271 GHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVSE 450
GHP P R+ + +++L + + + + +A DE+ H DY+ + S
Sbjct: 20 GHPESPRRLEVIYDMLEDRDMQGRFQDVPAREARMDELHLIHLPDYVNRVAS-------- 71
Query: 451 YNKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAA--VKLNKQASEICINWGGGLHHAKK 624
+M+ + D G Y+ L+AGG A V K + + G HHA+
Sbjct: 72 -TARMEYSCLDPDTDTSPGSYKAALLAAGGLCEAISMVASGKLDNAFALVRPPG-HHAEA 129
Query: 625 SEASGFCYVNDIVLGI--LELLKYHQRVLYIDIDVHHGDGVEXAFYTTDRVM 774
+ GFC N++ +G + + QR+L ID D+HHG+G + +F T ++
Sbjct: 130 DRSKGFCLFNNVAIGARYAQTALHLQRILIIDWDLHHGNGTQHSFETDPSIL 181
>UniRef50_UPI00015BAE44 Cluster: histone deacetylase superfamily;
n=1; Ignicoccus hospitalis KIN4/I|Rep: histone
deacetylase superfamily - Ignicoccus hospitalis KIN4/I
Length = 326
Score = 66.5 bits (155), Expect = 7e-10
Identities = 29/59 (49%), Positives = 36/59 (61%)
Frame = +1
Query: 601 GGLHHAKKSEASGFCYVNDIVLGILELLKYHQRVLYIDIDVHHGDGVEXAFYTTDRVMT 777
GGLHHA K A+GFC ND+ + L + RV Y+D DVHHGDG + FY V+T
Sbjct: 113 GGLHHAGKCRAAGFCPANDVAVLAEALARKGYRVAYLDFDVHHGDGTQEIFYERSDVLT 171
>UniRef50_Q12GF8 Cluster: Histone deacetylase superfamily; n=6;
Burkholderiales|Rep: Histone deacetylase superfamily -
Polaromonas sp. (strain JS666 / ATCC BAA-500)
Length = 353
Score = 66.5 bits (155), Expect = 7e-10
Identities = 37/99 (37%), Positives = 52/99 (52%), Gaps = 3/99 (3%)
Frame = +1
Query: 490 CPVFDGLYEFCQLSAGGSVAAA---VKLNKQASEICINWGGGLHHAKKSEASGFCYVNDI 660
CP+ + SA +VAAA + A +C G HHA + ASGFCYVN+
Sbjct: 128 CPIGPHTWHSVLRSAHSAVAAADAVCQTGDAAYALCRPSG---HHACRDSASGFCYVNNS 184
Query: 661 VLGILELLKYHQRVLYIDIDVHHGDGVEXAFYTTDRVMT 777
LL+++ RV +D+D HHGDG + FY + V+T
Sbjct: 185 ACAAHRLLQHYGRVAVLDVDAHHGDGTQHIFYDSADVLT 223
>UniRef50_P53973 Cluster: Histone deacetylase HDA1; n=7;
Saccharomycetales|Rep: Histone deacetylase HDA1 -
Saccharomyces cerevisiae (Baker's yeast)
Length = 706
Score = 66.5 bits (155), Expect = 7e-10
Identities = 37/142 (26%), Positives = 76/142 (53%), Gaps = 6/142 (4%)
Frame = +1
Query: 367 ATADEMTKFHSDDYIRFLRSIRPDNVSEYNKQMQRFNVGEDCPVFDGLYEFCQLSAGGSV 546
AT++E+ + H+ +++ F+ S + E K+ ++ G+ + Y +L GG++
Sbjct: 126 ATSEEILEVHTKEHLEFIESTEKMSREELLKETEK---GDSVYFNNDSYASARLPCGGAI 182
Query: 547 AA--AVKLNKQASEICINWGGGLHHAKKSEASGFCYVNDIVLGILELLKYH----QRVLY 708
A AV + + + + G HHA+ A GFC +++ + +LK + +R++
Sbjct: 183 EACKAVVEGRVKNSLAVVRPPG-HHAEPQAAGGFCLFSNVAVAAKNILKNYPESVRRIMI 241
Query: 709 IDIDVHHGDGVEXAFYTTDRVM 774
+D D+HHG+G + +FY D+V+
Sbjct: 242 LDWDIHHGNGTQKSFYQDDQVL 263
>UniRef50_A4JTS4 Cluster: Histone deacetylase superfamily; n=3;
Bacteria|Rep: Histone deacetylase superfamily -
Burkholderia vietnamiensis (strain G4 / LMG 22486)
(Burkholderiacepacia (strain R1808))
Length = 376
Score = 66.1 bits (154), Expect = 9e-10
Identities = 50/172 (29%), Positives = 77/172 (44%), Gaps = 4/172 (2%)
Frame = +1
Query: 274 HPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVSEY 453
H P R L+ G+ + RP AT +++ +FH+ +Y+ +R++ E
Sbjct: 37 HIEHPDSKRRFAELISVSGMNDHLVNIRPELATREDLLRFHTPEYVDKIRTLSEGRGGE- 95
Query: 454 NKQMQRFNVGEDCPVFDGLYEFCQLSAGG--SVAAAVKLNKQASEICINWGGGLHHAKKS 627
GE P G YE LS GG S+ +V + +N G HHA
Sbjct: 96 --------AGEHTPFGPGGYEIACLSTGGCISLLESVYRGDVRNGYSLNRPPG-HHAVAD 146
Query: 628 EASGFCYVNDIVLGI--LELLKYHQRVLYIDIDVHHGDGVEXAFYTTDRVMT 777
+ GFC + V+ I L+ + +RV +D DVHHG+ + AFY V+T
Sbjct: 147 QGRGFCIFGNGVVAIRRLQAMTGVKRVAVVDWDVHHGNSAQDAFYQDPSVLT 198
>UniRef50_UPI00015BB127 Cluster: histone deacetylase superfamily;
n=1; Ignicoccus hospitalis KIN4/I|Rep: histone
deacetylase superfamily - Ignicoccus hospitalis KIN4/I
Length = 345
Score = 65.7 bits (153), Expect = 1e-09
Identities = 47/172 (27%), Positives = 72/172 (41%), Gaps = 4/172 (2%)
Frame = +1
Query: 271 GHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVSE 450
GHP P R++ +L+ L +E+ P E+ H DY+ +++ + +
Sbjct: 19 GHPESPERVKAILDLMKRTKLPNYVEVRSPVPIDERELELVHDRDYVEYVKRV----IEA 74
Query: 451 YNKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAAVKLNKQASE----ICINWGGGLHHA 618
+ LY A G+VA A + + + G HHA
Sbjct: 75 GGGYLDPDTYASPTSWEPALY------AAGTVAYAAQRAVEGDHWLAFAAVRPPG--HHA 126
Query: 619 KKSEASGFCYVNDIVLGILELLKYHQRVLYIDIDVHHGDGVEXAFYTTDRVM 774
++SE GFC N++ L L + RV +DIDVH GDG FY TD V+
Sbjct: 127 RRSEGRGFCIFNNVALAAEVLRRRGMRVAVVDIDVHWGDGTAYIFYNTDEVL 178
>UniRef50_Q6AKN4 Cluster: Putative uncharacterized protein; n=1;
Desulfotalea psychrophila|Rep: Putative uncharacterized
protein - Desulfotalea psychrophila
Length = 341
Score = 65.3 bits (152), Expect = 2e-09
Identities = 42/147 (28%), Positives = 71/147 (48%), Gaps = 3/147 (2%)
Frame = +1
Query: 343 MEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVSEYNKQMQRFNVGEDCPVFDGLYEFC 522
+ I PH+A + + K HS+ Y+ +R E+ + F+ +D +
Sbjct: 43 LRIITPHEANTETIEKVHSNFYLSQIR--------EHALKSNPFSYDQDTYLMQQSLATA 94
Query: 523 QLSAGGSVAAAVKL-NKQASEICINWGGGLHHAKKSEASGFCYVNDIVLGILELLKYHQ- 696
QL+AGG + A ++ N + HHA+ GFC +N+I + L ++
Sbjct: 95 QLAAGGCLEIADQIMNGEIDHGFALIRPPGHHAEPGRGMGFCILNNIAITAKYLQTHYNL 154
Query: 697 -RVLYIDIDVHHGDGVEXAFYTTDRVM 774
R+L ID DVHHG+G + FY T++V+
Sbjct: 155 SRILIIDFDVHHGNGTQEVFYDTNQVL 181
>UniRef50_Q94EJ2 Cluster: Histone deacetylase 8; n=14;
Magnoliophyta|Rep: Histone deacetylase 8 - Arabidopsis
thaliana (Mouse-ear cress)
Length = 377
Score = 65.3 bits (152), Expect = 2e-09
Identities = 46/173 (26%), Positives = 83/173 (47%), Gaps = 5/173 (2%)
Frame = +1
Query: 274 HPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVSEY 453
HP R+R ++L + + + A E+ FH+ +YI + + E
Sbjct: 39 HPENADRVRNMLSILRRGPIAPHVNWFTGLPAIVSELLMFHTSEYI--------EKLVEA 90
Query: 454 NKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAAVKLNKQASEIC---INWGGGLHHAKK 624
+K +R + + G +E L+AG +++A + +I + G HH++
Sbjct: 91 DKSGERCEIAAGTFMSPGSWEAALLAAGTTLSAMQHILDCHGKIAYALVRPPG--HHSQP 148
Query: 625 SEASGFCYVNDIVLGILELLKYHQ--RVLYIDIDVHHGDGVEXAFYTTDRVMT 777
++A G+C++N+ L + L RV IDIDVH+G+G FYT+D+V+T
Sbjct: 149 TQADGYCFLNNAALAVKLALNSGSCSRVAVIDIDVHYGNGTAEGFYTSDKVLT 201
>UniRef50_A0Y3M1 Cluster: Histone deacetylase family protein; n=1;
Alteromonadales bacterium TW-7|Rep: Histone deacetylase
family protein - Alteromonadales bacterium TW-7
Length = 299
Score = 64.9 bits (151), Expect = 2e-09
Identities = 46/130 (35%), Positives = 62/130 (47%), Gaps = 2/130 (1%)
Frame = +1
Query: 355 RPHKATADEMTKFHSDDYIRFLRSIRPDNVSEYNKQMQRFNVGEDCPVFDGLYEFCQLSA 534
+P KA ++ HS+ YI + N+S+ K +++ P L E LS
Sbjct: 44 QPAKARPSQLALCHSEHYIN---NFLTGNLSD--KAIKKMGF----PYSAQLVERTLLSV 94
Query: 535 GGSVAAAVKLNKQASEICINWGGGLHHAKKSEASGFCYVNDIVLGILELLKYH--QRVLY 708
GGS+ AA + K S + N GG HHA SGFC ND+ + LL H + VL
Sbjct: 95 GGSIQAAEEALK--SGLTCNLSGGYHHAYSDYGSGFCIFNDLAIAATHLLSTHKAKTVLI 152
Query: 709 IDIDVHHGDG 738
D DVH GDG
Sbjct: 153 FDCDVHQGDG 162
>UniRef50_Q015Q9 Cluster: Histone deacetylase HDA110 isoform 2; n=2;
Ostreococcus|Rep: Histone deacetylase HDA110 isoform 2 -
Ostreococcus tauri
Length = 487
Score = 64.9 bits (151), Expect = 2e-09
Identities = 49/179 (27%), Positives = 89/179 (49%), Gaps = 11/179 (6%)
Frame = +1
Query: 271 GHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVSE 450
GH +P R R+ N + GL + E R +AT +E+ + HS +++ F+ S E
Sbjct: 119 GHFERPARHRVVVNEMRADGLESRCERLRCREATVEELERAHSKEHVAFVASA----FDE 174
Query: 451 YNKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAAVKLNKQASEIC---INWGGGL---- 609
+ +Q GE+ VF F + +A G+ AA +++ +C ++ +
Sbjct: 175 DGESVQ-IMTGEN--VFGDDIFFTRHTAAGARMAAGSVSEACLSVCRGDVDRAYAVVRPP 231
Query: 610 -HHAKKSEASGFCYVNDIVLGILELLKYH---QRVLYIDIDVHHGDGVEXAFYTTDRVM 774
HHA ++A GFC+ N+ V+ + H ++V+ +D DVHHG+G++ + D +M
Sbjct: 232 GHHAVCAQAMGFCFFNNAVVAARAAMAEHADVKKVVILDWDVHHGNGIQDLTFDDDSIM 290
>UniRef50_Q9UBN7 Cluster: Histone deacetylase 6; n=38; Eutheria|Rep:
Histone deacetylase 6 - Homo sapiens (Human)
Length = 1215
Score = 64.9 bits (151), Expect = 2e-09
Identities = 46/165 (27%), Positives = 73/165 (44%), Gaps = 5/165 (3%)
Frame = +1
Query: 274 HPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVSEY 453
HP P RI L GL + P AT E+ HS +Y+ LR+ E
Sbjct: 500 HPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLTCHSAEYVGHLRATEKMKTREL 559
Query: 454 NKQMQRFNVGEDCPVFDGLYEFCQLSAGGS--VAAAVKLNKQASEICINWGGGLHHAKKS 627
+++ F+ CP + QL+ G + + AV + + + G HHA++
Sbjct: 560 HRESSNFDSIYICP---STFACAQLATGAACRLVEAVLSGEVLNGAAVVRPPG-HHAEQD 615
Query: 628 EASGFCYVNDIVLGI--LELLKYHQ-RVLYIDIDVHHGDGVEXAF 753
A GFC+ N + + + + H R+L +D DVHHG+G + F
Sbjct: 616 AACGFCFFNSVAVAARHAQTISGHALRILIVDWDVHHGNGTQHMF 660
Score = 49.2 bits (112), Expect = 1e-04
Identities = 43/164 (26%), Positives = 67/164 (40%), Gaps = 5/164 (3%)
Frame = +1
Query: 277 PMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVSEYN 456
P P R+ L+ GL + ++ A +E+ HS +YI + + + N E
Sbjct: 106 PEGPERLHAIKEQLIQEGLLDRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELR 165
Query: 457 KQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAAVKLNKQA---SEICINWGGGLHHAKKS 627
+ + + Y C A GSV V A + + I G HHA+ S
Sbjct: 166 VLADTY---DSVYLHPNSYS-CACLASGSVLRLVDAVLGAEIRNGMAIIRPPG-HHAQHS 220
Query: 628 EASGFCYVNDIVLGILELLKYHQ--RVLYIDIDVHHGDGVEXAF 753
G+C N + + + H+ RVL +D DVHHG G + F
Sbjct: 221 LMDGYCMFNHVAVAARYAQQKHRIRRVLIVDWDVHHGQGTQFTF 264
>UniRef50_Q1PVG5 Cluster: Similar to histone deacetylase; n=1;
Candidatus Kuenenia stuttgartiensis|Rep: Similar to
histone deacetylase - Candidatus Kuenenia
stuttgartiensis
Length = 313
Score = 64.5 bits (150), Expect = 3e-09
Identities = 51/172 (29%), Positives = 74/172 (43%), Gaps = 4/172 (2%)
Frame = +1
Query: 271 GHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVSE 450
GHP RI T L + + I +P A +E+ H YI ++ I D+
Sbjct: 18 GHPENARRIENTIKYLESDNFLAHVTIEKPRAALPEEIGFIHPKTYISTIQQIA-DSGGG 76
Query: 451 YNKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAAVKLNKQASE--ICINWGGGLHHAKK 624
+ + D V Y SAG ++ A + K ++ C+ G HHA
Sbjct: 77 W--------LDGDTAVSGHSYNVALYSAGAALTAIDLIMKGEAKNAFCLVRPPG-HHATP 127
Query: 625 SEASGFCYVNDIVLGILELLKYHQ--RVLYIDIDVHHGDGVEXAFYTTDRVM 774
GFC N++ + L K +Q R+L ID DVHHG+G + AFY VM
Sbjct: 128 DRGMGFCLFNNVAIAARYLQKNYQQKRILIIDWDVHHGNGTQDAFYVDPTVM 179
>UniRef50_Q7XAX9 Cluster: HDA1; n=3; Magnoliophyta|Rep: HDA1 - Zea
mays (Maize)
Length = 701
Score = 64.5 bits (150), Expect = 3e-09
Identities = 49/175 (28%), Positives = 80/175 (45%), Gaps = 8/175 (4%)
Frame = +1
Query: 274 HPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNV-SE 450
HP P R+R L G+ + + +A + HS +I+ ++ I +
Sbjct: 34 HPENPERLRSIWRKLNAAGVASRCVALKAKEAEDKYIASVHSKRHIKLMKEISSTIYDAS 93
Query: 451 YNKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAAVKL--NKQASEICINWGGGLHHAKK 624
NK ++FN + G E L+AG + A K+ + +S I + G HHA+
Sbjct: 94 RNKIARKFN---SIYLNKGSSESAVLAAGSVIEVAEKVAAGELSSAIALVRPPG-HHAEH 149
Query: 625 SEASGFCYVNDIVLGILELLKYH-----QRVLYIDIDVHHGDGVEXAFYTTDRVM 774
EA GFC N++ + LL +++L +D DVHHG+G + FY RV+
Sbjct: 150 DEAMGFCLFNNVAVAANYLLNERPDLGIKKILIVDWDVHHGNGTQKMFYDDPRVL 204
>UniRef50_A3CT27 Cluster: Histone deacetylase superfamily; n=2;
Methanoculleus marisnigri JR1|Rep: Histone deacetylase
superfamily - Methanoculleus marisnigri (strain ATCC
35101 / DSM 1498 / JR1)
Length = 330
Score = 64.5 bits (150), Expect = 3e-09
Identities = 43/139 (30%), Positives = 68/139 (48%), Gaps = 1/139 (0%)
Frame = +1
Query: 358 PHKATADEMTKFHSDDYIRFLRSIRPDNVSEYNKQMQRFNVGEDCPVFDGLYEFCQLSAG 537
P +AT D++ H++ +I +RS E R+ + D V G ++ + G
Sbjct: 42 PERATVDDLALVHTERHIEGVRSF----CRECPPGRARY-LDPDTYVTAGSFDAALYATG 96
Query: 538 GSVAAAVK-LNKQASEICINWGGGLHHAKKSEASGFCYVNDIVLGILELLKYHQRVLYID 714
+ A + L+ + S + G HHA A GFC N++ + + L RV +D
Sbjct: 97 AAWQAVERALDGEHSFALVRPPG--HHAAPDRAMGFCLFNNVAVATAKALLSIGRVAVVD 154
Query: 715 IDVHHGDGVEXAFYTTDRV 771
D+HHG+G E AFYT+DRV
Sbjct: 155 WDLHHGNGTEEAFYTSDRV 173
>UniRef50_P28606 Cluster: Uncharacterized 34.1 kDa protein in glnA
3'region; n=15; Cyanobacteria|Rep: Uncharacterized 34.1
kDa protein in glnA 3'region - Synechococcus sp. (strain
PCC 7002) (Agmenellum quadruplicatum)
Length = 310
Score = 64.5 bits (150), Expect = 3e-09
Identities = 47/170 (27%), Positives = 73/170 (42%), Gaps = 2/170 (1%)
Frame = +1
Query: 274 HPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVSEY 453
H + R+ H LLL G+ + ++Y+P + H DY+
Sbjct: 29 HRFPMPKFRLLHGLLLEDGVIQPEQVYQPQLPDRAWLELVHEPDYVTAYCQ------GTL 82
Query: 454 NKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAAVKLNKQASEICINWGGGLHHAKKSEA 633
+ QR +G P G+ + + GG++ A +L + C N GG HHA
Sbjct: 83 TPKAQR-RIG--LPWSAGVVQRTLTAVGGTILTA-QLALEHGLAC-NTAGGTHHAFPGYG 137
Query: 634 SGFCYVNDIVLG--ILELLKYHQRVLYIDIDVHHGDGVEXAFYTTDRVMT 777
SGFC +ND+ + ++ QR+L +D+DVH GDG F V T
Sbjct: 138 SGFCILNDLAIATRTIQQRGLAQRILIVDLDVHQGDGTAFIFQDDPTVFT 187
>UniRef50_UPI0000F2E91A Cluster: PREDICTED: similar to histone
deacetylase 6,; n=1; Monodelphis domestica|Rep:
PREDICTED: similar to histone deacetylase 6, -
Monodelphis domestica
Length = 1143
Score = 63.7 bits (148), Expect = 5e-09
Identities = 43/167 (25%), Positives = 78/167 (46%), Gaps = 7/167 (4%)
Frame = +1
Query: 274 HPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVSEY 453
HP +P RI + GL + + AT E+ HS++YI +R+ +
Sbjct: 575 HPERPERIAQIAQHHMELGLTPRCFVLPARSATNQELLACHSEEYIERIRATSGLKPRDL 634
Query: 454 NKQMQRFNVGEDCPVFDGLYEFC--QLSAGGS--VAAAVKLNKQASEICINWGGGLHHAK 621
+++ +N ++ + FC QL+AG + + A+ + + + I G HHA+
Sbjct: 635 HREGTSYN-----SIYISPHSFCCAQLAAGAACRLVEAILAREVQNGLAIVRPPG-HHAE 688
Query: 622 KSEASGFCYVNDIVLG---ILELLKYHQRVLYIDIDVHHGDGVEXAF 753
+ A GFC+ N + + E+ R+L +D D+HHG+G + F
Sbjct: 689 RDAACGFCFFNSVAVAARHAQEVAGRALRILIVDWDIHHGNGTQHIF 735
Score = 50.8 bits (116), Expect = 4e-05
Identities = 40/168 (23%), Positives = 71/168 (42%), Gaps = 6/168 (3%)
Frame = +1
Query: 268 QGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVS 447
+ P +P R++ L L + + AT +E+ HS +Y+ + S S
Sbjct: 172 ESFPERPERLQAVQEQLARDCLLERCLLIEAQPATPEELQLVHSQEYVDLMASTPQMTES 231
Query: 448 EYNKQMQRFNVGEDCPVFDGLYEF-CQLSAGGS---VAAAVKLNKQASEICINWGGGLHH 615
E ++ V+ F C L A G+ + A+ + + + + G HH
Sbjct: 232 ERRALSDTYD-----SVYLHPNSFPCALLATGALLRLVDALMTGEIRNGLAVVRPPG-HH 285
Query: 616 AKKSEASGFCYVNDIVLGILELLKYHQ--RVLYIDIDVHHGDGVEXAF 753
A++ +G+C N+I + + H R+L +D DVHHG G + F
Sbjct: 286 AQRESMNGYCMFNNIAIAARYAQERHHVARILIVDWDVHHGQGTQFIF 333
>UniRef50_A3JH86 Cluster: Deacetylase / probable acetylpolyamine
aminohydrolase; n=1; Marinobacter sp. ELB17|Rep:
Deacetylase / probable acetylpolyamine aminohydrolase -
Marinobacter sp. ELB17
Length = 376
Score = 63.7 bits (148), Expect = 5e-09
Identities = 52/171 (30%), Positives = 77/171 (45%), Gaps = 7/171 (4%)
Frame = +1
Query: 286 PHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVSEYNKQM 465
P R NLL GL ++ + +P AT +++ FH+ Y+ L +
Sbjct: 48 PESKRRLKNLLEVSGLIDELVVVKPPPATREDLEYFHTGRYLDELEK----------GDL 97
Query: 466 QRFNVGEDC-PVFDGLYEFCQLSAGGSVAA----AVKLNKQASEICINWGGGLHHAKKSE 630
Q G DC P G + SAG ++AA A+ + ++A +C G HHA+
Sbjct: 98 QGGGDGGDCAPYTAGSLAAAKQSAGLAIAAVEDVALGIRRRAYALCRPPG---HHAESDR 154
Query: 631 ASGFCYVNDIVLGILELLKYHQ--RVLYIDIDVHHGDGVEXAFYTTDRVMT 777
GFC + +I + I Q RV +D DVHHG+G + AFY V T
Sbjct: 155 GRGFCLLGNIPVAIKRARALGQIGRVAVLDWDVHHGNGTQSAFYDDPDVFT 205
>UniRef50_UPI0000D56143 Cluster: PREDICTED: similar to CG6170-PA,
isoform A; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to CG6170-PA, isoform A - Tribolium castaneum
Length = 824
Score = 62.9 bits (146), Expect = 9e-09
Identities = 28/57 (49%), Positives = 39/57 (68%), Gaps = 2/57 (3%)
Frame = +1
Query: 610 HHAKKSEASGFCYVNDIVLGILELL-KYH-QRVLYIDIDVHHGDGVEXAFYTTDRVM 774
HHA+ +A G+C+VN+I + LL KY +RVL +D D+HHG+G + FY DRVM
Sbjct: 588 HHAEHDKAMGYCFVNNIAVAANYLLDKYEVERVLIVDFDIHHGNGTQNMFYENDRVM 644
Score = 54.8 bits (126), Expect = 2e-06
Identities = 21/57 (36%), Positives = 37/57 (64%), Gaps = 2/57 (3%)
Frame = +1
Query: 610 HHAKKSEASGFCYVNDIVLGILELLK--YHQRVLYIDIDVHHGDGVEXAFYTTDRVM 774
HHA ++E +G+CY N++ + +L+ + +RV+ +D DVHHG G + FY + V+
Sbjct: 184 HHAMENEYNGYCYFNNVAIAAESVLREGHSKRVMIVDFDVHHGQGTQRMFYERNDVL 240
>UniRef50_Q5QWS4 Cluster: Histone deacetylase/AcuC/AphA family
protein; n=2; Idiomarina|Rep: Histone
deacetylase/AcuC/AphA family protein - Idiomarina
loihiensis
Length = 311
Score = 62.5 bits (145), Expect = 1e-08
Identities = 33/86 (38%), Positives = 48/86 (55%), Gaps = 3/86 (3%)
Frame = +1
Query: 529 SAGGSVAAA-VKLNKQASEICINWGGGLHHAKKSEASGFCYVNDIVLGILELLKYHQ--R 699
SAGG++ + L K + I++ GG HHA K SGFC +ND+ + E+L H +
Sbjct: 98 SAGGTLLTTELALTKG---VAIHFSGGYHHAHKDWGSGFCLLNDLAIACNEILVRHPKLK 154
Query: 700 VLYIDIDVHHGDGVEXAFYTTDRVMT 777
++ +D DVH GDG F +RV T
Sbjct: 155 IVVLDTDVHQGDGTATLFENDNRVFT 180
>UniRef50_Q18477 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 282
Score = 62.5 bits (145), Expect = 1e-08
Identities = 40/132 (30%), Positives = 63/132 (47%), Gaps = 2/132 (1%)
Frame = +1
Query: 349 IYRPHKATADEMTKFHSDDYIRFLRSIRPDNVSEYNKQMQRFNVGEDCPVFDGLYEFCQL 528
+ P+ T +E+T+ H Y++ +R+ P ++ ++ C + L +L
Sbjct: 9 LVEPNLPTFEELTRVHDRKYLKSVRN--PIKAAQI-VEIPFVGCLPPCIIESKLLHPLRL 65
Query: 529 SAGGSVAAAVKLNKQASEICINWGGGLHHAKKSEASGFCYVNDIVLGILELL--KYHQRV 702
AGG+V AA K IN GGG HHA S GFC+ DI + I +L K
Sbjct: 66 QAGGTVLAANLALKHGW--AINVGGGFHHASHSGGGGFCFYADITMAIFDLFDKKAIANA 123
Query: 703 LYIDIDVHHGDG 738
+ +D+D H G+G
Sbjct: 124 IVVDLDAHQGNG 135
>UniRef50_A6FY71 Cluster: Histone deacetylase superfamily protein;
n=1; Plesiocystis pacifica SIR-1|Rep: Histone
deacetylase superfamily protein - Plesiocystis pacifica
SIR-1
Length = 623
Score = 62.1 bits (144), Expect = 2e-08
Identities = 47/158 (29%), Positives = 72/158 (45%), Gaps = 4/158 (2%)
Frame = +1
Query: 316 LLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVSEYNKQMQRFNVGEDCP 495
L+ GL + RP A ++ + H Y+ L S V E Q F GE P
Sbjct: 59 LVREGLVGPECVVRPTPAAFVKLARVHDQAYLERLESAA---VME-----QAF--GEVVP 108
Query: 496 V--FDGLYEFCQLSAGGSVAAAVKLNKQASEICINWGGGLHHAKKSEASGFCYVNDIVLG 669
+ E + GG++ AA + + ++ +N GGG HHA++ A GFC +ND+ +
Sbjct: 109 PGPATAIVELQRAMVGGTMLAA-RAAWRRHKLAVNLGGGFHHARRDRAGGFCLLNDVAVA 167
Query: 670 ILELLK--YHQRVLYIDIDVHHGDGVEXAFYTTDRVMT 777
I EL + + +D+D+H GDG F V T
Sbjct: 168 IAELRASGFTGPISVVDLDLHDGDGTRLMFADDPSVWT 205
>UniRef50_Q7RB89 Cluster: Histone deacetylase/AcuC/AphA family
protein, putative; n=6; Plasmodium|Rep: Histone
deacetylase/AcuC/AphA family protein, putative -
Plasmodium yoelii yoelii
Length = 461
Score = 62.1 bits (144), Expect = 2e-08
Identities = 33/115 (28%), Positives = 61/115 (53%), Gaps = 2/115 (1%)
Frame = +1
Query: 439 NVSEYNKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAAVKLNKQASEICINWGGGLHHA 618
N+ + N++++ + + +F L + G++ +++ K + +C++ GGG HH+
Sbjct: 224 NIIKNNEEIKLYELN----LFSDLIARYLIEINGTILSSLLALKHS--MCMHIGGGNHHS 277
Query: 619 KKSEASGFCYVNDIVLGILELLKYH--QRVLYIDIDVHHGDGVEXAFYTTDRVMT 777
K+ + GFC NDI + + LL Y + V+ +D+DVH GDG F V T
Sbjct: 278 KRDKGDGFCIFNDIAIAVDFLLFYKIVKNVIILDVDVHQGDGTAEIFQNHQNVKT 332
>UniRef50_Q7U7V3 Cluster: Putative histone deacetylase/AcuC/AphA
family protein; n=4; Synechococcus|Rep: Putative histone
deacetylase/AcuC/AphA family protein - Synechococcus sp.
(strain WH8102)
Length = 323
Score = 61.7 bits (143), Expect = 2e-08
Identities = 49/170 (28%), Positives = 74/170 (43%), Gaps = 2/170 (1%)
Frame = +1
Query: 274 HPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVSEY 453
H + R+ LLL+ + + +I RP ++ + H Y + + D +S
Sbjct: 37 HRFPMAKFRLLRRLLLDEQVLQANQIRRPLSIPRRDLERIHRRSYHQ---AFSRDQLSR- 92
Query: 454 NKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAAVKLNKQASEICINWGGGLHHAKKSEA 633
+ +R + P L + LS GG++ A +L Q C + GG HHA
Sbjct: 93 -SEQRRIGL----PATRPLVQRTWLSVGGTLLTA-RLALQHGIAC-HLAGGTHHAHPGFG 145
Query: 634 SGFCYVNDIVLGILELLKYH--QRVLYIDIDVHHGDGVEXAFYTTDRVMT 777
SGFC ND+ LL QR+L +D+DVH GDG F R+ T
Sbjct: 146 SGFCIFNDVATTARVLLDNGEVQRLLVVDLDVHQGDGTAACFADEPRITT 195
>UniRef50_Q0LE47 Cluster: Histone deacetylase superfamily; n=1;
Herpetosiphon aurantiacus ATCC 23779|Rep: Histone
deacetylase superfamily - Herpetosiphon aurantiacus ATCC
23779
Length = 345
Score = 61.7 bits (143), Expect = 2e-08
Identities = 49/174 (28%), Positives = 78/174 (44%), Gaps = 7/174 (4%)
Frame = +1
Query: 274 HPMKPHRIRMTHNLLL-NYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVSE 450
HP +R+R H +L +Y L + + P ATA E+ H ++ L+
Sbjct: 19 HPENANRLRAIHAMLAADYELQQHLTPLAPRHATAAEIEAVHVPSHLPTLQ--------- 69
Query: 451 YNKQMQRFNVGEDCPVF--DGLYEFCQLSAGGSVAA--AVKLNKQASEICINWGGGLHHA 618
+M +F D + E QL+AGG++ A AV + A+ + G HHA
Sbjct: 70 ---RMAQFGDWADAETYILPDSVEIAQLAAGGAIVATDAVLSGRHANSFALVRPPG-HHA 125
Query: 619 KKSEASGFCYVNDIVLGILELLKYH--QRVLYIDIDVHHGDGVEXAFYTTDRVM 774
+A GFC N+ + + + +RV +D DVHHG+G + FY V+
Sbjct: 126 TADQAMGFCLFNNAAIAAAFAQREYGLKRVAILDWDVHHGNGTQDIFYQNPDVL 179
>UniRef50_Q8RX28 Cluster: Histone deacetylase 5; n=4;
Magnoliophyta|Rep: Histone deacetylase 5 - Arabidopsis
thaliana (Mouse-ear cress)
Length = 660
Score = 61.7 bits (143), Expect = 2e-08
Identities = 47/179 (26%), Positives = 83/179 (46%), Gaps = 10/179 (5%)
Frame = +1
Query: 268 QGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVS 447
+ HP P RIR+ L G+ ++ + KA + H+ D++ ++SI
Sbjct: 44 EDHPECPDRIRVIWEKLQLAGVSQRCVVLGSSKAEDKHLQLVHTKDHVNLVKSISTKQ-K 102
Query: 448 EYNKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAAVKLNKQASEICINWGGGL-----H 612
+Y + + + G E L+AG + VKL ++ +E ++ G + H
Sbjct: 103 DYRRNRIASQLNS-IYLNGGSSEAAYLAAG----SVVKLAEKVAEGELDCGFAIVRPPGH 157
Query: 613 HAKKSEASGFCYVNDIVLGILELLKYH-----QRVLYIDIDVHHGDGVEXAFYTTDRVM 774
HA+ EA GFC N++ + LL +++L +D DVHHG+G + F+ RV+
Sbjct: 158 HAEADEAMGFCLFNNVAVAASFLLNERPDLGVKKILIVDWDVHHGNGTQKMFWKDPRVL 216
>UniRef50_A4YNH4 Cluster: Acetylpolyamine aminohydrolase; n=15;
Proteobacteria|Rep: Acetylpolyamine aminohydrolase -
Bradyrhizobium sp. (strain ORS278)
Length = 374
Score = 61.3 bits (142), Expect = 3e-08
Identities = 24/56 (42%), Positives = 36/56 (64%)
Frame = +1
Query: 610 HHAKKSEASGFCYVNDIVLGILELLKYHQRVLYIDIDVHHGDGVEXAFYTTDRVMT 777
HHA + ASGFC++N+ + L + H+RV +D+DVHHG+G + FY V+T
Sbjct: 190 HHAYRDIASGFCFMNNSAIAAAHLRQRHERVAILDVDVHHGNGTQGIFYERPDVLT 245
>UniRef50_Q23M98 Cluster: Histone deacetylase family protein; n=1;
Tetrahymena thermophila SB210|Rep: Histone deacetylase
family protein - Tetrahymena thermophila SB210
Length = 2774
Score = 61.3 bits (142), Expect = 3e-08
Identities = 46/174 (26%), Positives = 78/174 (44%), Gaps = 7/174 (4%)
Frame = +1
Query: 274 HPMKPHRIRMTHNLLLNYGLYRK--MEIYRPHKATADEMTKF-HSDDYIRFLRSIRPDNV 444
H P R++ N L GL + + I K + K+ H D+YI F+ + P+
Sbjct: 2149 HVECPARLQSIFNHLTTQGLLKSPLVHIVDKLKPAEKSIVKYAHDDNYIEFIEGMWPEKT 2208
Query: 445 SEYNKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAAVKL-NKQ-ASEICINWGGGLHHA 618
+ K++ + + D Y L GG + + ++ +KQ + CI G H
Sbjct: 2209 KK--KEIYMLDTYFNQSSKDAAY----LGVGGVIESVDRIISKQWKNAFCIIRPPGHHSG 2262
Query: 619 KKSEASGFCYVNDIVLGILELLKYH--QRVLYIDIDVHHGDGVEXAFYTTDRVM 774
+ +GFC+ N++ + L K H ++VL D D+HHGDG + F V+
Sbjct: 2263 ESKVCTGFCFFNNVAIAAKYLQKNHGVKKVLIFDWDIHHGDGTQHIFQDDPNVL 2316
>UniRef50_Q5KL48 Cluster: Histone deacetylase clr3, putative; n=1;
Filobasidiella neoformans|Rep: Histone deacetylase clr3,
putative - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 737
Score = 61.3 bits (142), Expect = 3e-08
Identities = 47/172 (27%), Positives = 80/172 (46%), Gaps = 10/172 (5%)
Frame = +1
Query: 271 GHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDY------IRFLRSIR 432
GHP P RI+ L GL R+M+ + +++ H ++ L +
Sbjct: 90 GHPEDPMRIKRIFTRLAEQGLIRRMKRLDFEEVKFEQVLLVHGEEMWDKVQATELLSDQQ 149
Query: 433 PDNVSEYNKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAA--AVKLNKQASEICINWGGG 606
++ EY Q+ + E +LSAGG + A +V N+ + I G
Sbjct: 150 IQDMKEYYDQLSLYVCRETA-------HCARLSAGGVIQACRSVCKNEVRNAFAIVRPPG 202
Query: 607 LHHAKKSEASGFCYVNDIVLGILELLK--YHQRVLYIDIDVHHGDGVEXAFY 756
HHA+ +E GFC+ N++ + E+ + ++VL +D DVHHG+G + AF+
Sbjct: 203 -HHAEPNEHMGFCFFNNVAVATREMQREGLAKKVLILDWDVHHGNGTQRAFW 253
>UniRef50_UPI0001555A7F Cluster: PREDICTED: similar to histone
deacetylase 6, partial; n=1; Ornithorhynchus
anatinus|Rep: PREDICTED: similar to histone deacetylase
6, partial - Ornithorhynchus anatinus
Length = 803
Score = 60.9 bits (141), Expect = 3e-08
Identities = 45/165 (27%), Positives = 74/165 (44%), Gaps = 5/165 (3%)
Frame = +1
Query: 274 HPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVSEY 453
HP P RI GL ++ A+ E+ HS +Y+ +R+ E
Sbjct: 316 HPELPQRISRIAQRHAELGLTQRCRALPARLASDQELLLCHSPEYVEQMRATSGLKPREL 375
Query: 454 NKQMQRFNVGEDCPVFDGLYEFCQLSAGG--SVAAAVKLNKQASEICINWGGGLHHAKKS 627
+++ +R+N + + QL+AG S+ AV + + + I G HHA++
Sbjct: 376 HREGERYN---SIYIAPRSFHCAQLAAGSACSLVEAVLDGQVRNGVAIVRPPG-HHAERD 431
Query: 628 EASGFCYVNDIVLG---ILELLKYHQRVLYIDIDVHHGDGVEXAF 753
A GFC+ N + + +L RVL +D DVHHG+G + F
Sbjct: 432 TACGFCFFNSVAVAARHAQQLAGRPLRVLILDWDVHHGNGTQHMF 476
Score = 48.0 bits (109), Expect = 3e-04
Identities = 31/133 (23%), Positives = 59/133 (44%), Gaps = 4/133 (3%)
Frame = +1
Query: 367 ATADEMTKFHSDDYIRFLRSIRPDNVSEYNKQMQRFNVGEDCPVFDGLYEFCQLSAGG-- 540
AT +E+ + HS ++++ + S + + E + + + Y +L+ G
Sbjct: 50 ATQEELLRVHSQEFLKLMESTQQMSEEELRALADTY---DSVFLHPNSYACARLATGTVL 106
Query: 541 SVAAAVKLNKQASEICINWGGGLHHAKKSEASGFCYVNDIVLGILELLKYHQ--RVLYID 714
+ V + + + + G HHA++ G+C N + + + HQ RVL +D
Sbjct: 107 QLVDMVMAGEVRNGLAVVRPPG-HHAQRERMDGYCMFNHLAVSARHAQEKHQVERVLIVD 165
Query: 715 IDVHHGDGVEXAF 753
DVHHG G + F
Sbjct: 166 WDVHHGQGTQRIF 178
>UniRef50_Q8F254 Cluster: Histone deacetylase family protein; n=4;
Leptospira|Rep: Histone deacetylase family protein -
Leptospira interrogans
Length = 302
Score = 60.9 bits (141), Expect = 3e-08
Identities = 38/170 (22%), Positives = 76/170 (44%), Gaps = 2/170 (1%)
Frame = +1
Query: 274 HPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVSEY 453
H + +M ++L+ + IY+P A +++ H+ +++ S+ ++Y
Sbjct: 23 HVFPARKYQMVYDLVKRDSKLSNLYIYKPDLAKTKDLSLVHTQEFLDDFFSLNITERTQY 82
Query: 454 NKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAAVKLNKQASEICINWGGGLHHAKKSEA 633
+ + P+ + L+ GG++ + K + + GGG HH+ A
Sbjct: 83 S----------ELPLTKQIVHSFVLAVGGTILSMELAQKY--KFVYHIGGGFHHSMPDRA 130
Query: 634 SGFCYVNDIVLGILELLKYH--QRVLYIDIDVHHGDGVEXAFYTTDRVMT 777
GFCY+ND + K + +++L+ID+D+H G+G F V T
Sbjct: 131 EGFCYLNDAAIASKLYQKEYPDKKILFIDLDLHQGNGNSFIFQNDPDVFT 180
>UniRef50_Q62HN7 Cluster: Acetylpolyamine aminohydrolase; n=53;
Proteobacteria|Rep: Acetylpolyamine aminohydrolase -
Burkholderia mallei (Pseudomonas mallei)
Length = 340
Score = 60.9 bits (141), Expect = 3e-08
Identities = 33/105 (31%), Positives = 49/105 (46%)
Frame = +1
Query: 460 QMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAAVKLNKQASEICINWGGGLHHAKKSEASG 639
Q R CPV + + SA ++AAA + + + G HHA+ A G
Sbjct: 106 QAARHLADGSCPVGEHTWRAAYWSAQSALAAAAVRDGAPAAYALCRPPG-HHARVDAAGG 164
Query: 640 FCYVNDIVLGILELLKYHQRVLYIDIDVHHGDGVEXAFYTTDRVM 774
FCY+N+ + L H RV +D D+HHG G++ FY V+
Sbjct: 165 FCYLNNAAIAAQALRARHARVAVLDTDMHHGQGIQEIFYARRDVL 209
>UniRef50_Q4FNF7 Cluster: Histone deacetylase family protein; n=5;
Bacteria|Rep: Histone deacetylase family protein -
Pelagibacter ubique
Length = 309
Score = 60.9 bits (141), Expect = 3e-08
Identities = 52/174 (29%), Positives = 82/174 (47%), Gaps = 6/174 (3%)
Frame = +1
Query: 271 GHPMKPHRIRMTHNLLLNYGLYRKMEIYR-PHKATADEMTKFHSDDYIRFLRSIRPDNVS 447
GHP K R+ + + L K I++ P K + H+ DYI F+ P+
Sbjct: 19 GHPEKIDRVTVVIDNFKK--LDNKNLIWKKPSKFNRSLLEITHNSDYINFVEKSFPEKGL 76
Query: 448 EYNKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAAVK--LNKQ-ASEICINWGGGLHHA 618
+ + D V G + L A GS+ A+ NK + C G HHA
Sbjct: 77 SF--------LDGDTIVSPGSKD-ATLDAVGSIITAIDGVQNKDFKNAFCAVRPPG-HHA 126
Query: 619 KKSEASGFCYVNDIVLGILELL-KYH-QRVLYIDIDVHHGDGVEXAFYTTDRVM 774
+K++A GFC N++ +G L+ KY +++ ID DVHHG+G + FY ++V+
Sbjct: 127 EKNKAMGFCIYNNVAVGANYLINKYKLKKIAIIDFDVHHGNGTQDIFYDNEKVL 180
>UniRef50_Q22CW6 Cluster: Histone deacetylase family protein; n=1;
Tetrahymena thermophila SB210|Rep: Histone deacetylase
family protein - Tetrahymena thermophila SB210
Length = 359
Score = 60.9 bits (141), Expect = 3e-08
Identities = 43/166 (25%), Positives = 71/166 (42%), Gaps = 5/166 (3%)
Frame = +1
Query: 274 HPMKPHRIRMTHNLLLNYGLYRKMEIYRP-HKATADEMTKFHSDDYIRFLRSIRPDNVSE 450
HP P RI L GL+ ++++ D + K H D Y+ + + P+ +
Sbjct: 28 HPECPERIEKIIENLKKTGLWSQLDVINQVEPIQKDILNKVHRDSYVDLVEQMWPEGCEK 87
Query: 451 YNKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAA--VKLNKQASEICINWGGGLHHAKK 624
N + + + G F LS+G + + +K + C G H
Sbjct: 88 ENMVLNGCYYNK----YTGQSAF--LSSGAVIQSIDLIKSKSWHTAFCCVRPPGHHSGAS 141
Query: 625 SEASGFCYVNDIVLGILELL-KYH-QRVLYIDIDVHHGDGVEXAFY 756
+ SGFC+ N++V+G L KY +++ D DVHHGDG + Y
Sbjct: 142 QQCSGFCFFNNVVVGAKYLREKYSVKKIAIFDFDVHHGDGTQALTY 187
>UniRef50_Q7Z8L6 Cluster: Putative histone deacetylase; n=2;
Pleosporales|Rep: Putative histone deacetylase -
Cochliobolus carbonum (Bipolaris zeicola)
Length = 847
Score = 60.5 bits (140), Expect = 5e-08
Identities = 40/142 (28%), Positives = 71/142 (50%), Gaps = 6/142 (4%)
Frame = +1
Query: 367 ATADEMTKFHSDDYIRFLRSIRPDNVSEYNKQMQRFNVGEDCPVFDGLYEFCQLSAGGSV 546
AT E+ H++++ ++S + E + +R + + + YE +L+AGG++
Sbjct: 182 ATRPEILLIHTEEHYDLVKSFQNMTSDELKFEAERL---DSIYLNNSTYECAKLAAGGAI 238
Query: 547 AA--AVKLNKQASEICINWGGGLHHAKKSEASGFCYVNDIVLGILELLKYH----QRVLY 708
A AV + I I G HHA+ + SGFC N++ + + ++VL
Sbjct: 239 EACKAVVQGAVRNAIAIIRPPG-HHAESDQPSGFCIFNNVPIATRVCQNAYPETCRKVLI 297
Query: 709 IDIDVHHGDGVEXAFYTTDRVM 774
+D DVHHG+G++ AFY V+
Sbjct: 298 LDWDVHHGNGIQHAFYDDPNVL 319
>UniRef50_A5DRS6 Cluster: Histone deacetylase HDA1; n=7;
Saccharomycetales|Rep: Histone deacetylase HDA1 -
Lodderomyces elongisporus (Yeast) (Saccharomyces
elongisporus)
Length = 906
Score = 60.5 bits (140), Expect = 5e-08
Identities = 37/143 (25%), Positives = 73/143 (51%), Gaps = 6/143 (4%)
Frame = +1
Query: 364 KATADEMTKFHSDDYIRFLRSIRPDNVSEYNKQMQRFNVGEDCPVFDGLYEFCQLSAGGS 543
+AT +E+ + HS+ ++ ++S E ++ G+ V + Y +LS GG+
Sbjct: 269 EATIEEILEVHSEKHLEHIQSTETMTKDELLRETA---TGDSIYVNNDSYFSAKLSCGGT 325
Query: 544 VAA--AVKLNKQASEICINWGGGLHHAKKSEASGFCYVNDIVLGILELLKYH----QRVL 705
+ A AV + + + G HHA+ + GFC +++ + +LK + +R++
Sbjct: 326 IEACKAVIEGRVKNSLAAVRPPG-HHAEPDDPGGFCLFSNVAVAAKNILKSYPESVRRIV 384
Query: 706 YIDIDVHHGDGVEXAFYTTDRVM 774
+D D+HHG+G + +FY RV+
Sbjct: 385 ILDWDIHHGNGTQKSFYDDPRVL 407
>UniRef50_Q08BS8 Cluster: Zgc:152701; n=9; Euteleostomi|Rep:
Zgc:152701 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 1023
Score = 60.1 bits (139), Expect = 6e-08
Identities = 47/179 (26%), Positives = 84/179 (46%), Gaps = 12/179 (6%)
Frame = +1
Query: 274 HPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRF-----LRSIRPD 438
HP RI+ + L GL + E R KAT +E+ HS+ ++ LR
Sbjct: 620 HPEHAGRIQSIWSRLQETGLRGQCECIRGRKATLEELQTVHSEAHVLLYGTNPLRQKLDS 679
Query: 439 NVSEYNKQMQRFNVGEDCP-VFDGLYEF--CQLSAGGSVAAAVKL--NKQASEICINWGG 603
+V+ ++ +G D +++ ++ +L+ G V K+ + + +
Sbjct: 680 SVTPMFVRLPCGGIGVDSDTIWNEVHSSSAARLAVGSVVDLVFKVASGELRNGFAVVRPP 739
Query: 604 GLHHAKKSEASGFCYVNDIVLG--ILELLKYHQRVLYIDIDVHHGDGVEXAFYTTDRVM 774
G HHA++S GFCY N + + +L+ ++L +D DVHHG+G + AFY+ V+
Sbjct: 740 G-HHAEESTPMGFCYFNSVAIAAKLLQQRLNVSKILIVDWDVHHGNGTQQAFYSDPNVL 797
>UniRef50_Q8D858 Cluster: Histone deacetylase/AcuC/AphA family
protein; n=31; Gammaproteobacteria|Rep: Histone
deacetylase/AcuC/AphA family protein - Vibrio vulnificus
Length = 312
Score = 60.1 bits (139), Expect = 6e-08
Identities = 43/145 (29%), Positives = 67/145 (46%), Gaps = 3/145 (2%)
Frame = +1
Query: 352 YRPHKATADEMTKFHSDDYIRFLRS-IRPDNVSEYNKQMQRFNVGEDCPVFDGLYEFCQL 528
Y+P + + + + H +Y+ L + + P +M+R P + L E
Sbjct: 52 YQPEALSIEAIKQVHQQEYVDLLTTGLLPA------AKMRRIGF----PWSEKLIERTLT 101
Query: 529 SAGGSVAAAVKLNKQASEICINWGGGLHHAKKSEASGFCYVNDIVLGILELLKYH--QRV 702
S G+V A K + + I+ GG HHA SGFC ND+V+ + L++ +V
Sbjct: 102 STAGTVLTAEKALQHG--VAIHLSGGYHHAHFDYGSGFCLFNDLVMAAHKALEHGSVDKV 159
Query: 703 LYIDIDVHHGDGVEXAFYTTDRVMT 777
L ID DVHHGDG D ++T
Sbjct: 160 LIIDSDVHHGDGTATLCQRRDDIVT 184
>UniRef50_Q63YT0 Cluster: Histone deacetylase family protein; n=12;
Burkholderia|Rep: Histone deacetylase family protein -
Burkholderia pseudomallei (Pseudomonas pseudomallei)
Length = 370
Score = 60.1 bits (139), Expect = 6e-08
Identities = 45/165 (27%), Positives = 76/165 (46%), Gaps = 4/165 (2%)
Frame = +1
Query: 292 RIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVSEYNKQMQR 471
R+ T LL G+ ++ +AT +++ + H +Y+R L + + +Q+ R
Sbjct: 40 RLAYTKQLLDAVGMTERLTRVAFARATDEQLLRVHRPEYLRQLA----EACAVAGEQVVR 95
Query: 472 FNVGEDCPVFDGLYEFCQLSAGGSVAA--AVKLNKQASEICINWGGGLHHAKKSEASGFC 645
+G+D + +L+AG + AA AV + G HHA A G+C
Sbjct: 96 --LGDDAAGSASTEDVARLAAGAACAAVDAVMTGPLRQAYALIRPSG-HHAGADFAMGYC 152
Query: 646 YVNDIVLGILELLKYH--QRVLYIDIDVHHGDGVEXAFYTTDRVM 774
Y N++ + H +RV +D DVHHG+G + AFY V+
Sbjct: 153 YYNNVAIAARHAQAAHGVERVAIVDWDVHHGNGTQQAFYDDPSVL 197
>UniRef50_A3JI99 Cluster: Putative aminohydrolase; n=1; Marinobacter
sp. ELB17|Rep: Putative aminohydrolase - Marinobacter
sp. ELB17
Length = 344
Score = 60.1 bits (139), Expect = 6e-08
Identities = 26/65 (40%), Positives = 39/65 (60%)
Frame = +1
Query: 580 EICINWGGGLHHAKKSEASGFCYVNDIVLGILELLKYHQRVLYIDIDVHHGDGVEXAFYT 759
+IC+ G HHA+KS A GFCY+N+ + L + Q++ ID D+HHG G++ FY
Sbjct: 151 QICLTRPAG-HHARKSAAGGFCYLNNAAIIAEHLRQKFQKIAIIDTDMHHGQGIQEIFYD 209
Query: 760 TDRVM 774
V+
Sbjct: 210 RKDVL 214
>UniRef50_Q6C4P0 Cluster: Similar to sp|P53973 Saccharomyces
cerevisiae YNL021w HDA1 histone deacetylase A; n=1;
Yarrowia lipolytica|Rep: Similar to sp|P53973
Saccharomyces cerevisiae YNL021w HDA1 histone
deacetylase A - Yarrowia lipolytica (Candida lipolytica)
Length = 748
Score = 60.1 bits (139), Expect = 6e-08
Identities = 49/186 (26%), Positives = 89/186 (47%), Gaps = 19/186 (10%)
Frame = +1
Query: 274 HPMKPHRIRMTHNLLLNYGL-----YRKMEIYRP-------HKATADEMTKFHSDDYIRF 417
HP P RI + L++ GL Y +E P +A+ DE+ + H+ ++ F
Sbjct: 116 HPEDPRRIFSVYKALVDAGLVVDPEYLGLEDIGPLMEKIPIREASLDEVLEVHTPAHVDF 175
Query: 418 LRSIRPDNVSEYNKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVA---AAVKLNKQASEIC 588
L S N + ++ ++ G+ + + +LS GG++ A ++ N + +
Sbjct: 176 LASTEKMNRPQLLEEGEK---GDSVYFNNESFSAGKLSCGGTIETCRAVIERNVKNAIAV 232
Query: 589 INWGGGLHHAKKSEASGFCYVNDIVLGILELLKYH----QRVLYIDIDVHHGDGVEXAFY 756
+ G HHA+ +GFC +++ + LLK + +R+L +D DVHHG+G + AF
Sbjct: 233 VRPPG--HHAEPGNPAGFCMFSNVAVAAKVLLKRYPERVKRILILDWDVHHGNGTQRAFL 290
Query: 757 TTDRVM 774
RV+
Sbjct: 291 DDPRVL 296
>UniRef50_UPI000069F4DB Cluster: Histone deacetylase 7a (HD7a).; n=3;
Xenopus tropicalis|Rep: Histone deacetylase 7a (HD7a). -
Xenopus tropicalis
Length = 893
Score = 59.7 bits (138), Expect = 8e-08
Identities = 54/186 (29%), Positives = 80/186 (43%), Gaps = 19/186 (10%)
Frame = +1
Query: 274 HPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRF-----LRSIRPD 438
HP RI+ + L GL E R KAT +E+ H++ ++ L ++ D
Sbjct: 477 HPEHAGRIQSIWSRLQERGLRNNCECIRGRKATLEELQSVHTETHVLLYGTNPLNRLKLD 536
Query: 439 NVSEYNKQMQRFNVGEDCPVF----DGLYEFCQLSAGGSVAAAVKLN---KQASEICINW 597
N QR V C D ++ S AA ++ K AS N
Sbjct: 537 NRKLAGILSQRMFVMLPCGGLGVDSDTIWNELHSSNAARWAAGSVIDLAFKVASRELKN- 595
Query: 598 GGGL-----HHAKKSEASGFCYVNDIVLGI--LELLKYHQRVLYIDIDVHHGDGVEXAFY 756
G L HHA S A GFC+ N + + L+L + +++L +D DVHHG+G + FY
Sbjct: 596 GFALVRPPGHHADPSTAMGFCFFNSVAIAAKQLQLRRDVRKILIVDWDVHHGNGTQRVFY 655
Query: 757 TTDRVM 774
T V+
Sbjct: 656 TDPNVL 661
>UniRef50_Q02CA3 Cluster: Histone deacetylase superfamily; n=1;
Solibacter usitatus Ellin6076|Rep: Histone deacetylase
superfamily - Solibacter usitatus (strain Ellin6076)
Length = 312
Score = 59.7 bits (138), Expect = 8e-08
Identities = 47/165 (28%), Positives = 74/165 (44%), Gaps = 4/165 (2%)
Frame = +1
Query: 274 HPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVSEY 453
HP P R + L GL KM AT +E+T H+ DY++ RS +V+
Sbjct: 20 HPECPARFDAVLDGLDRAGLLAKMLRVEARDATQEELTLCHTPDYLKTARS----DVASG 75
Query: 454 NKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAA--AVKLNKQASEICINWGGGLHHAKKS 627
+ + G D + ++ ++GG + A AV + C G HHA +
Sbjct: 76 RPYL---STG-DTDITPNSWDVAVRASGGVLNAVDAVLTGAARNAFCAVRPPG-HHANAA 130
Query: 628 EASGFCYVNDIVLGILELLKYH--QRVLYIDIDVHHGDGVEXAFY 756
GFC +N++ + + H +RV +D DVHHG+G + FY
Sbjct: 131 RGMGFCLLNNVAIAARYAQRRHGIERVAIVDWDVHHGNGTQDIFY 175
>UniRef50_A7HFZ2 Cluster: Histone deacetylase superfamily; n=4;
Cystobacterineae|Rep: Histone deacetylase superfamily -
Anaeromyxobacter sp. Fw109-5
Length = 589
Score = 59.7 bits (138), Expect = 8e-08
Identities = 43/157 (27%), Positives = 73/157 (46%), Gaps = 3/157 (1%)
Frame = +1
Query: 280 MKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVSEYNK 459
M+P R L G I+ P + D++ + H+ + + L RP+NV+
Sbjct: 41 MEPRRADFALWWLRECGAVPTRAIHSPRRIAYDDLARVHTPELLESLG--RPENVAHI-- 96
Query: 460 QMQRFNVG-EDCPVFDGLYEFCQLSAGGSVAAAVKLNKQASEICINWGGGLHHAKKSEAS 636
F V D PV D + +L+ G +++A + + + +N GG HHA A
Sbjct: 97 ----FAVDPSDVPV-DEVMTTIRLACGATLSAT-RETLRTKQPALNLLGGFHHASPGAAG 150
Query: 637 GFCYVNDIVLGILELLK--YHQRVLYIDIDVHHGDGV 741
GFC VND+ + + + + RV+ +D+D H DG+
Sbjct: 151 GFCPVNDVAVALAAVRAEGFTDRVVVLDLDAHPPDGI 187
>UniRef50_A1C5E8 Cluster: Histone deacetylase hda1; n=8;
Eurotiomycetidae|Rep: Histone deacetylase hda1 -
Aspergillus clavatus
Length = 805
Score = 59.7 bits (138), Expect = 8e-08
Identities = 51/185 (27%), Positives = 85/185 (45%), Gaps = 18/185 (9%)
Frame = +1
Query: 274 HPMKPHRIRMTHNLLLNYGLYRKMEIYRP-----------HKATADEMTKFHSDDYIRFL 420
HP P RI + L GL E RP AT +E++ H+ D+ F+
Sbjct: 155 HPEDPRRIYYIYKELCRAGLVDDPESSRPLVARPLKRIHARNATEEEVSLVHTPDHFAFV 214
Query: 421 RSIRPDNVSEYNKQMQRFNVGEDCPVFDGL-YEFCQLSAGGSVAA--AVKLNKQASEICI 591
S + ++S+ ++ D F+ L + LS GG++ AV K + I +
Sbjct: 215 ESTK--DMSD--DELIALEHTRDSIYFNKLTFASALLSTGGAIETCLAVATRKVKNAIAV 270
Query: 592 NWGGGLHHAKKSEASGFCYVNDIVLGIL----ELLKYHQRVLYIDIDVHHGDGVEXAFYT 759
G HHA+ + GFC N++ + +L + +++L +D DVHHG+G++ AFY
Sbjct: 271 IRPPG-HHAEHDKTMGFCLFNNVSVAARVCQKQLGESCRKILIVDWDVHHGNGIQKAFYD 329
Query: 760 TDRVM 774
V+
Sbjct: 330 DPNVL 334
>UniRef50_Q5LRW9 Cluster: Acetylpolyamine aminohydrolase; n=7;
Rhodobacteraceae|Rep: Acetylpolyamine aminohydrolase -
Silicibacter pomeroyi
Length = 341
Score = 59.3 bits (137), Expect = 1e-07
Identities = 32/97 (32%), Positives = 50/97 (51%), Gaps = 1/97 (1%)
Frame = +1
Query: 490 CPVFDGLYEFCQLSAGGSVAAA-VKLNKQASEICINWGGGLHHAKKSEASGFCYVNDIVL 666
CP+ +G +E SA ++ A + + + S ++ G HHA A GFC++N+ +
Sbjct: 117 CPIAEGTWEAAYWSAQSAITGADLIIQGERSAYVLSRPPG-HHAFGDLAGGFCFLNNSAI 175
Query: 667 GILELLKYHQRVLYIDIDVHHGDGVEXAFYTTDRVMT 777
L R +DIDVHHG+G + FY D V+T
Sbjct: 176 AAERLRAAGLRPAILDIDVHHGNGTQGIFYERDDVLT 212
>UniRef50_Q5LQF5 Cluster: Histone deacetylase/AcuC/AphA family
protein; n=3; Rhodobacteraceae|Rep: Histone
deacetylase/AcuC/AphA family protein - Silicibacter
pomeroyi
Length = 371
Score = 59.3 bits (137), Expect = 1e-07
Identities = 49/174 (28%), Positives = 72/174 (41%), Gaps = 6/174 (3%)
Frame = +1
Query: 274 HPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVSEY 453
H P R NL+ GL+ + RP +A + + H +I L S+ +
Sbjct: 43 HFENPETKRRLQNLVQATGLWEHLSHLRPKRAADEVIRMVHPQSHIDHLASVCERGGGD- 101
Query: 454 NKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAAVKLNKQASE----ICINWGGGLHHAK 621
GE P E +L+ GG + A + A+E +C G HHA
Sbjct: 102 --------AGELTPAGPASLEIARLAVGGVIVAMDAVMTGAAENAYVLCRPPG---HHAL 150
Query: 622 KSEASGFCYVNDIVLGILELLKYH--QRVLYIDIDVHHGDGVEXAFYTTDRVMT 777
A GFC + + LGI + K + R+ +D DVHHG+G E F V+T
Sbjct: 151 PDLAMGFCLLANAALGIRHVQKTYGLTRIAVVDWDVHHGNGTEAVFLDDPGVLT 204
>UniRef50_Q1IMW0 Cluster: Histone deacetylase superfamily; n=2;
Acidobacteria|Rep: Histone deacetylase superfamily -
Acidobacteria bacterium (strain Ellin345)
Length = 298
Score = 59.3 bits (137), Expect = 1e-07
Identities = 34/85 (40%), Positives = 45/85 (52%), Gaps = 2/85 (2%)
Frame = +1
Query: 529 SAGGSVAAAVKLNKQASEICINWGGGLHHAKKSEASGFCYVNDIVLGILELLK--YHQRV 702
S GG+++A ++ +S GG HHA +SE SG+C NDI + IL L QR
Sbjct: 92 SVGGTLSAG--MDALSSGFGGTLAGGTHHAFRSEGSGYCVFNDIAIAILYLRSKGLAQRA 149
Query: 703 LYIDIDVHHGDGVEXAFYTTDRVMT 777
ID+DVH GDG F V+T
Sbjct: 150 AVIDLDVHQGDGTAQIFQNDALVLT 174
>UniRef50_A4BCK9 Cluster: Deacetylase, including yeast histone
deacetylase and acetoin utilization protein; n=1;
Reinekea sp. MED297|Rep: Deacetylase, including yeast
histone deacetylase and acetoin utilization protein -
Reinekea sp. MED297
Length = 308
Score = 58.8 bits (136), Expect = 1e-07
Identities = 44/173 (25%), Positives = 70/173 (40%), Gaps = 4/173 (2%)
Frame = +1
Query: 268 QGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVS 447
+ HP P R + L+ GL ++ + +AT ++ + H Y+ D +
Sbjct: 19 EDHPESPRRTEIIRERLIESGLMEQLLPLKAFQATKSQILRVHHSTYV--------DQLD 70
Query: 448 EYNKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAAVKLNKQASE--ICINWGGGLHHAK 621
N + D + YE L+AG + A + A C G HHA+
Sbjct: 71 RINPKYGLIQADPDTLMGPYTYEASYLAAGAGIQAVDGIMNGAFNRAFCAVRPPG-HHAE 129
Query: 622 KSEASGFCYVNDIVLGILELLKYHQ--RVLYIDIDVHHGDGVEXAFYTTDRVM 774
+ GFC+ N+I + LK+H+ RV ID DVH +G + VM
Sbjct: 130 PNVTMGFCFFNNIAVAAEHALKHHKLSRVAIIDFDVHQCNGTIEMYENRPEVM 182
>UniRef50_Q4PCR1 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 727
Score = 58.8 bits (136), Expect = 1e-07
Identities = 48/176 (27%), Positives = 81/176 (46%), Gaps = 9/176 (5%)
Frame = +1
Query: 274 HPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSD----DYIRFLRSIRPDN 441
HP +P RI L+ +M+ P + A+E K D + ++ L PD
Sbjct: 103 HPERPLRIFKIFMKFKESNLFARMKRV-PIREVAEEEVKLVHDHGIWEGVQRLAFYHPDV 161
Query: 442 VSEYNKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAA--AVKLNKQASEICINWGGGLHH 615
+ E Q+Q + + +LS GG++ AV + + I G HH
Sbjct: 162 LKE---QVQLLETNSSLYINEHSAYAARLSCGGAIELVNAVAAGQIQNGFAIVRPPG-HH 217
Query: 616 AKKSEASGFCYVNDIVLGILELLKYH---QRVLYIDIDVHHGDGVEXAFYTTDRVM 774
A+ ++ GFC+ N++ + +L+ H ++VL +D DVHHG+G + AF D V+
Sbjct: 218 AEPQKSMGFCFFNNVAVATRVVLRRHAHIKKVLILDWDVHHGNGTQRAFEYDDNVL 273
>UniRef50_Q31HC2 Cluster: Histone deacetylase family protein; n=1;
Thiomicrospira crunogena XCL-2|Rep: Histone deacetylase
family protein - Thiomicrospira crunogena (strain XCL-2)
Length = 306
Score = 58.0 bits (134), Expect = 2e-07
Identities = 42/162 (25%), Positives = 73/162 (45%), Gaps = 4/162 (2%)
Frame = +1
Query: 271 GHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVSE 450
GHP R+ L + L AT ++ + HS + L+ P+N
Sbjct: 18 GHPENAQRVVRIEQALTDARLLSNTLHKSILPATEIDVLRVHSSPFWETLKKHLPENGF- 76
Query: 451 YNKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAAVK--LNKQASEICINWGGGLHHAKK 624
+ ED + G E L+A G++ A+ ++++A + N HHA++
Sbjct: 77 -------VKIDEDTSLSPGSLESA-LAASGAMLTAIDAIMHREAKQAFCNIRPPGHHAER 128
Query: 625 SEASGFCYVNDIVLGILELLKYH--QRVLYIDIDVHHGDGVE 744
+ GFC +N I +G L+ + +R++ +D DVHHG+G E
Sbjct: 129 NRPMGFCLINHIAIGAAYALEKYALERIVIVDFDVHHGNGTE 170
>UniRef50_Q15WQ0 Cluster: Histone deacetylase superfamily; n=3;
Gammaproteobacteria|Rep: Histone deacetylase superfamily
- Pseudoalteromonas atlantica (strain T6c / BAA-1087)
Length = 306
Score = 58.0 bits (134), Expect = 2e-07
Identities = 43/146 (29%), Positives = 64/146 (43%), Gaps = 2/146 (1%)
Frame = +1
Query: 346 EIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVSEYNKQMQRFNVGEDCPVFDGLYEFCQ 525
+ ++PH T ++ + +S DY+ L D K M+R P + L
Sbjct: 49 QFHQPHALTPSQLNRVYSPDYVNDLTRGMLDP-----KAMRRIGF----PWSEQLIARSL 99
Query: 526 LSAGGSVAAAVKLNKQASEICINWGGGLHHAKKSEASGFCYVNDIVLGILELLKYH--QR 699
+ GG+V + + +N GG HHA + SGFC ND+ L L +L+ ++
Sbjct: 100 TAVGGTVLTSSLALEHGK--ALNLTGGYHHAFANFGSGFCLFNDLYLAALNVLQTPTIRK 157
Query: 700 VLYIDIDVHHGDGVEXAFYTTDRVMT 777
VL D DVH GDG RV T
Sbjct: 158 VLIFDCDVHQGDGTAKLASNNKRVFT 183
>UniRef50_A5W9E9 Cluster: Histone deacetylase superfamily; n=17;
Gammaproteobacteria|Rep: Histone deacetylase superfamily
- Pseudomonas putida F1
Length = 317
Score = 58.0 bits (134), Expect = 2e-07
Identities = 50/172 (29%), Positives = 75/172 (43%), Gaps = 4/172 (2%)
Frame = +1
Query: 274 HPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYI-RFLRSIRPDNVSE 450
H + R+ H+ L+ GL + RP D + H YI R++ E
Sbjct: 32 HRFPMDKFRLLHDHLVGSGLTTDQALLRPDICPNDILALAHDRSYIERYMNG-------E 84
Query: 451 YNKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAAVKLNKQASEICINWGGGLHHAKKSE 630
+++ QR +G P + L + GGS+ A ++ Q C + GG HHA
Sbjct: 85 LSREDQR-RLG--LPWSEALARRTVRAVGGSLLTA-EMALQHGIAC-HLAGGTHHAHYDH 139
Query: 631 ASGFCYVNDIVL---GILELLKYHQRVLYIDIDVHHGDGVEXAFYTTDRVMT 777
+GFC ND+ + +LE + H RVL D DVH GDG + T +T
Sbjct: 140 PAGFCIFNDLAVISRYLLEAGRVH-RVLIFDCDVHQGDGTARILHDTPEAIT 190
>UniRef50_Q17I08 Cluster: Histone deacetylase; n=1; Aedes aegypti|Rep:
Histone deacetylase - Aedes aegypti (Yellowfever
mosquito)
Length = 1112
Score = 58.0 bits (134), Expect = 2e-07
Identities = 50/181 (27%), Positives = 77/181 (42%), Gaps = 14/181 (7%)
Frame = +1
Query: 274 HPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFL--RSIRPDNVS 447
HP R++ L+ GL + + R KAT +E+ HS+ + I V
Sbjct: 699 HPEHSGRLQSIWARLMETGLAARCDKLRSRKATQEELQSVHSEAHSLLFGTNQINRQKVD 758
Query: 448 EYNKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAA--VKLNKQASEICINWGGGL---- 609
R G D + +A +AA + L +A++ I G +
Sbjct: 759 ASGVSFVRLGCGGVGVDLDTTWNEHHTAAAARMAAGCVIDLCYKAAKGEIRNGFAVVRPP 818
Query: 610 -HHAKKSEASGFCYVNDIVLGILELLKYH-----QRVLYIDIDVHHGDGVEXAFYTTDRV 771
HHA+ + A GFC+ N I + +LL+ QRVL +D DVHHG+G + FY V
Sbjct: 819 GHHAEPNAAMGFCFFNSIAIAA-KLLRQRLSSEIQRVLVVDWDVHHGNGTQQVFYDDPSV 877
Query: 772 M 774
+
Sbjct: 878 L 878
>UniRef50_Q0W553 Cluster: Putative acetoin utilization protein; n=1;
uncultured methanogenic archaeon RC-I|Rep: Putative
acetoin utilization protein - Uncultured methanogenic
archaeon RC-I
Length = 331
Score = 57.6 bits (133), Expect = 3e-07
Identities = 31/97 (31%), Positives = 50/97 (51%), Gaps = 1/97 (1%)
Frame = +1
Query: 487 DCPVFDGLYEFCQLSAGGSVAAAVKLNKQASEICINWGGGL-HHAKKSEASGFCYVNDIV 663
D + G + +L+AG ++ A ++ K E+ HHA A GFC N+
Sbjct: 79 DTEMTAGSLDAARLAAGAALDAVEEVRK-GRELAFGLVRPPGHHALPGRAMGFCIFNNAA 137
Query: 664 LGILELLKYHQRVLYIDIDVHHGDGVEXAFYTTDRVM 774
+G L ++++VL +D DVHHG+G + FY T V+
Sbjct: 138 IGAARALDHYRKVLVVDWDVHHGNGTQQIFYRTPDVL 174
>UniRef50_Q4SMC8 Cluster: Chromosome 3 SCAF14553, whole genome shotgun
sequence; n=2; Tetraodontidae|Rep: Chromosome 3
SCAF14553, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 1155
Score = 57.2 bits (132), Expect = 4e-07
Identities = 48/179 (26%), Positives = 82/179 (45%), Gaps = 12/179 (6%)
Frame = +1
Query: 274 HPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRF-----LRSIRPD 438
HP RI+ + L GL + E R KAT +E+ HS+ ++ LR
Sbjct: 726 HPEHAGRIQSIWSRLQETGLRAQCECIRGRKATLEELQTVHSEAHVLLYGTNPLRQKLDC 785
Query: 439 NVSEYNKQMQRFNVGEDCP-VFDGLYEFCQLS-AGGSVAAAV---KLNKQASEICINWGG 603
+++ ++ +G D +++ ++ A GSVA V + + +
Sbjct: 786 SITPMFVRLPCGGIGVDSDTIWNEVHSSSAARLAVGSVAELVFKVATRELKNGFAVVRPP 845
Query: 604 GLHHAKKSEASGFCYVNDIVLG--ILELLKYHQRVLYIDIDVHHGDGVEXAFYTTDRVM 774
G HHA++S GFCY N + + +L+ ++L +D DVHHG+G + AFY V+
Sbjct: 846 G-HHAEESTPMGFCYFNSVAIAAKLLQQRLNINKILIVDWDVHHGNGTQQAFYDDPSVL 903
>UniRef50_Q1IJP8 Cluster: Histone deacetylase superfamily; n=1;
Acidobacteria bacterium Ellin345|Rep: Histone
deacetylase superfamily - Acidobacteria bacterium
(strain Ellin345)
Length = 357
Score = 57.2 bits (132), Expect = 4e-07
Identities = 42/162 (25%), Positives = 65/162 (40%), Gaps = 2/162 (1%)
Frame = +1
Query: 274 HPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVSEY 453
H + + LL G+ + P AT ++ HS Y+ D + E
Sbjct: 41 HVFPTQKYELVKQELLEEGVASTQDFLTPTPATEADVLLVHSHFYV--------DKLIE- 91
Query: 454 NKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAAVKLNKQASEICINWGGGLHHAKKSEA 633
R + + P + GG++ AA + + N GGG HHA
Sbjct: 92 GTLTAREELALEIPYSHEAVQAFLWHTGGTILAAERALSDG--VAFNLGGGFHHAYPDHG 149
Query: 634 SGFCYVNDIVLGILELLKYH--QRVLYIDIDVHHGDGVEXAF 753
GFC ++D+ + I +L K QRV+ +D DVH G+G F
Sbjct: 150 EGFCMIHDVAVAIRKLQKQGRIQRVMTLDCDVHQGNGTAVIF 191
>UniRef50_Q09C86 Cluster: Histone deacetylase/AcuC/AphA family
protein; n=2; Cystobacterineae|Rep: Histone
deacetylase/AcuC/AphA family protein - Stigmatella
aurantiaca DW4/3-1
Length = 587
Score = 57.2 bits (132), Expect = 4e-07
Identities = 45/165 (27%), Positives = 75/165 (45%), Gaps = 3/165 (1%)
Frame = +1
Query: 268 QGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVS 447
QGHP P R++ ++L + ++ P ATA E++ H+ + + L +
Sbjct: 265 QGHPESPARLQSILSVLARTPV-AGTQVRSPRSATAAELSAVHTPELRQALLGMAG---- 319
Query: 448 EYNKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAA--VKLNKQASEICINWGGGLHHAK 621
R + ED + Y+ L+AG +V A V + + + G HHA+
Sbjct: 320 ------HRAVIDEDTRLSPDSYDAALLAAGAAVGAVEEVMAGRARNAFALVRPPG-HHAE 372
Query: 622 KSEASGFCYVNDIVLGILELLKYH-QRVLYIDIDVHHGDGVEXAF 753
A GFC N++ + + +RVL +D DVHHG+G + AF
Sbjct: 373 PGRAMGFCLFNNVAIAAEAGRRLGAERVLVLDWDVHHGNGTQAAF 417
>UniRef50_Q64BV4 Cluster: Acetoin utilization protein; n=5;
Archaea|Rep: Acetoin utilization protein - uncultured
archaeon GZfos26F9
Length = 351
Score = 57.2 bits (132), Expect = 4e-07
Identities = 43/168 (25%), Positives = 74/168 (44%), Gaps = 7/168 (4%)
Frame = +1
Query: 274 HPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVSEY 453
HP R+R L G+ K+ P KA+ +++ H+ +YI + ++
Sbjct: 23 HPETAERLRAIIRKLEETGIAEKLRRIIPTKASKEQLRYVHAPEYIEEVEAMCRRGGGAL 82
Query: 454 NKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAAVKLNKQASEI-----CINWGGGLHHA 618
+ D P+ + YE L+ GG A ++ +++ + I G HHA
Sbjct: 83 DP---------DTPLCEATYEIALLATGGVTKAGDEVMDESNSLKHVFALIRPPG--HHA 131
Query: 619 KKSEASGFCYVNDIVLGILELLKYH--QRVLYIDIDVHHGDGVEXAFY 756
++ GFC N+I + L + + RVL D DVHHG+G + F+
Sbjct: 132 TPNKGMGFCIFNNIAIATEHLKREYGINRVLIADWDVHHGNGTQRMFF 179
>UniRef50_UPI0000E463DB Cluster: PREDICTED: similar to histone
deacetylase-4; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to histone deacetylase-4 -
Strongylocentrotus purpuratus
Length = 1012
Score = 56.8 bits (131), Expect = 6e-07
Identities = 50/187 (26%), Positives = 85/187 (45%), Gaps = 18/187 (9%)
Frame = +1
Query: 268 QGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVS 447
Q HP P R++ L G+ + E R KA+ +E+ HS+ Y F + +
Sbjct: 643 QNHPEHPGRLQSIWARLHERGIVSRCERIRTRKASLEELQSCHSEGYTLFFGTSQTHKAK 702
Query: 448 EYNKQMQ---RFN--------VGEDCP-VFDGLYE--FCQLSAGGSVAAAVKL--NKQAS 579
++++ + N +G D V+ + +++AG + A K+ + +
Sbjct: 703 LDSRKLALIPKLNFTWLSCGGLGVDTDTVWHDIQSPGAVRIAAGAVIELAFKVATGELKN 762
Query: 580 EICINWGGGLHHAKKSEASGFCYVNDIVLGILEL-LKYH-QRVLYIDIDVHHGDGVEXAF 753
I G HHA+ S+A GFC+ N I + +L LK ++L ID DVHHG+ + F
Sbjct: 763 GFAIVRPPG-HHAETSQAMGFCFFNSIAIAAKQLRLKLKLNKILIIDWDVHHGNSTQKIF 821
Query: 754 YTTDRVM 774
Y V+
Sbjct: 822 YEDPHVL 828
>UniRef50_Q3ZWU5 Cluster: Histone deacetylase family protein; n=3;
Dehalococcoides|Rep: Histone deacetylase family protein
- Dehalococcoides sp. (strain CBDB1)
Length = 341
Score = 56.8 bits (131), Expect = 6e-07
Identities = 43/170 (25%), Positives = 69/170 (40%), Gaps = 3/170 (1%)
Frame = +1
Query: 274 HPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVSEY 453
H P R+ L +GL ++ P + E+ FH YI V E
Sbjct: 19 HVENPDRLLAIMEYLETHGLKDRLVHIEPKRVGMRELESFHKRSYI--------SRVEEV 70
Query: 454 NKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAAVK-LNKQASEICINWGGGLHHAKKSE 630
+ + +D + YE + GG + K L+++ + HHA
Sbjct: 71 GFSGGGW-LDQDTVISLDSYEAALYAVGGVIEGVDKVLSRELDSAFVLCRPPGHHALPEA 129
Query: 631 ASGFCYVNDIVLGILELLKYH--QRVLYIDIDVHHGDGVEXAFYTTDRVM 774
+ GFC N++ LG L L H +RV +D DVHHG+G++ R++
Sbjct: 130 SMGFCVFNNVALGALHALNKHKLKRVAVVDFDVHHGNGIQHVCLNDPRLI 179
>UniRef50_Q9A2B7 Cluster: Histone deacetylase family protein; n=9;
Alphaproteobacteria|Rep: Histone deacetylase family
protein - Caulobacter crescentus (Caulobacter
vibrioides)
Length = 304
Score = 56.4 bits (130), Expect = 7e-07
Identities = 43/145 (29%), Positives = 64/145 (44%), Gaps = 4/145 (2%)
Frame = +1
Query: 355 RPHKATADEMTKFHSDDYIRFL--RSIRPDNVSEYNKQMQRFNVGEDCPVFDGLYEFCQL 528
RP + + HS+DY+R + S+ PD V +G P + + +
Sbjct: 48 RPEPVDVETLCLAHSEDYVRGVIELSLPPDIVRR---------IG--MPNTESVATRARA 96
Query: 529 SAGGSVAAAVKLNKQASEICINWGGGLHHAKKSEASGFCYVNDIVLGILELLKYHQ--RV 702
+ GG++ AA +L + C N GG HHA +GFC ND+ + LL +
Sbjct: 97 ATGGTLLAA-RLALERGIAC-NTAGGSHHAAADAGAGFCVFNDVAVAARRLLAEGAIGKA 154
Query: 703 LYIDIDVHHGDGVEXAFYTTDRVMT 777
L +D+DVH GDG F V T
Sbjct: 155 LVVDLDVHQGDGTARIFENDPSVFT 179
>UniRef50_Q7ZYF0 Cluster: Hdac6-prov protein; n=2; Xenopus|Rep:
Hdac6-prov protein - Xenopus laevis (African clawed
frog)
Length = 1286
Score = 56.0 bits (129), Expect = 1e-06
Identities = 46/168 (27%), Positives = 69/168 (41%), Gaps = 8/168 (4%)
Frame = +1
Query: 274 HPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVSEY 453
HP P RI + GL + AT E+ HS YI+ + + +
Sbjct: 501 HPESPQRINQIFKRHKDLGLLERCSRLPSRLATQKELQMCHSLSYIQKIEASAHMKPRDL 560
Query: 454 NKQMQRFNVGEDCPVFDGLYEFCQLSAGGS--VAAAVKLNKQASEICINWGGGLHHAKKS 627
++ +N + Y +L+AG + V AV K + I I G HHA+
Sbjct: 561 HRLGDEYN---SIYINSKSYHSARLAAGSTFNVVEAVVTGKAQNGIGIVRPPG-HHAEPG 616
Query: 628 EASGFCYVNDIVLGILELLKYHQ------RVLYIDIDVHHGDGVEXAF 753
EA GFC+ N + L + RV+ +D DVHHG+G + F
Sbjct: 617 EACGFCFFNTVALAARYAQRLQSQSEDPLRVMILDWDVHHGNGTQHIF 664
Score = 54.4 bits (125), Expect = 3e-06
Identities = 43/174 (24%), Positives = 72/174 (41%), Gaps = 5/174 (2%)
Frame = +1
Query: 268 QGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVS 447
+ P P RI + + YGL + +A+ +E+ HS Y+ +RS + +
Sbjct: 98 ENFPECPGRIWAVRDKMAEYGLAERCVAVPAREASEEEILLIHSPQYVALMRSTQKMTMD 157
Query: 448 EYNKQMQRFNVGEDCPVFDGLYEFCQLSAGGSV---AAAVKLNKQASEICINWGGGLHHA 618
E R+ D C A GSV V+ + + + + G HHA
Sbjct: 158 ELRALSDRY----DSVYLHPTSFTCASLAVGSVLQLVDRVQHGEIRNGLAVVRPPG-HHA 212
Query: 619 KKSEASGFCYVNDIVLG--ILELLKYHQRVLYIDIDVHHGDGVEXAFYTTDRVM 774
+ +G+C N + + +L +RVL +D DVHHG G + F + V+
Sbjct: 213 HTDQMNGYCMFNQLAIAARYAQLTYGAKRVLIVDWDVHHGQGTQFIFESDPSVL 266
>UniRef50_Q00U49 Cluster: Histone deacetylase superfamily; n=3;
Ostreococcus|Rep: Histone deacetylase superfamily -
Ostreococcus tauri
Length = 749
Score = 56.0 bits (129), Expect = 1e-06
Identities = 50/176 (28%), Positives = 75/176 (42%), Gaps = 7/176 (3%)
Frame = +1
Query: 271 GHPMKPHRIRMTHNLLLNYGLYR-KMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVS 447
GH + ++ L N R K+E+ +++ H +Y+R + +S
Sbjct: 456 GHRFPMDKYQLARLALQNDDTLRGKIELRASPLVDIEDLEAAHCGEYVR---KVLTRTLS 512
Query: 448 EYNKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAAVK-LNKQASEICINWGGGLHHAKK 624
E + F +GE V L S GG+VA A + L + GG HHA +
Sbjct: 513 EQEVRTIGFPMGEQ-NVTRSL-----ASTGGTVACAREVLAGFGARAAAQLAGGTHHAYR 566
Query: 625 SEASGFCYVNDIVLGIL-----ELLKYHQRVLYIDIDVHHGDGVEXAFYTTDRVMT 777
GFC NDI I ELL +++L ID+DVH G+G F +V+T
Sbjct: 567 DRGEGFCVFNDIGTAIRVVQRDELLPRDRKILVIDLDVHQGNGTAKMFEHDQQVVT 622
>UniRef50_A6SGS8 Cluster: Putative uncharacterized protein; n=3;
Pezizomycotina|Rep: Putative uncharacterized protein -
Botryotinia fuckeliana B05.10
Length = 780
Score = 56.0 bits (129), Expect = 1e-06
Identities = 40/137 (29%), Positives = 71/137 (51%), Gaps = 7/137 (5%)
Frame = +1
Query: 385 TKFHSDDYIRFLRSIRPDNVSEYNKQMQRFNVG-EDCPVFDGLYEFCQLSAGGSVAAA-- 555
T FH D ++ L S+ + + E N QR++ G + V Y+ ++AGG++
Sbjct: 167 TAFHYD-WVESLLSMTSEELREAN---QRYDTGRKSLYVGPCTYDAALVAAGGAIETCKH 222
Query: 556 VKLNKQASEICINWGGGLHHAKKSEASGFCYVNDIVLG----ILELLKYHQRVLYIDIDV 723
V + + I I G HHA+++EA GFC N++ + + + + ++VL +D D+
Sbjct: 223 VVVGNVKNAIAIIRPPG-HHAEENEALGFCVFNNVPIAAKVCMADYPEICRKVLILDWDI 281
Query: 724 HHGDGVEXAFYTTDRVM 774
HHG+G + FY V+
Sbjct: 282 HHGNGTQNMFYDDPNVL 298
>UniRef50_Q2SC27 Cluster: Deacetylases, including yeast histone
deacetylase and acetoin utilization protein; n=1;
Hahella chejuensis KCTC 2396|Rep: Deacetylases,
including yeast histone deacetylase and acetoin
utilization protein - Hahella chejuensis (strain KCTC
2396)
Length = 318
Score = 55.6 bits (128), Expect = 1e-06
Identities = 32/86 (37%), Positives = 47/86 (54%), Gaps = 6/86 (6%)
Frame = +1
Query: 505 GLYEFCQLSAGGSVAAAVKLNKQASEICINWGGGLHHAKKSEASGFCYVNDIVLGILELL 684
GL + + G++ AA K ++ + I N GGG HHA + GFC+ +D L I +LL
Sbjct: 98 GLLTPAKYAVAGTITAAHKAIEEEA-IVFNLGGGFHHAFRDHGEGFCFFSDAALAI-QLL 155
Query: 685 KYHQR------VLYIDIDVHHGDGVE 744
+ +R VL ID+D H G+G E
Sbjct: 156 RAEKRLGSADEVLMIDLDAHRGNGFE 181
>UniRef50_Q1N4R7 Cluster: Deacetylases, including yeast histone
deacetylase and acetoin utilization protein; n=1;
Oceanobacter sp. RED65|Rep: Deacetylases, including
yeast histone deacetylase and acetoin utilization
protein - Oceanobacter sp. RED65
Length = 308
Score = 55.6 bits (128), Expect = 1e-06
Identities = 49/171 (28%), Positives = 67/171 (39%), Gaps = 4/171 (2%)
Frame = +1
Query: 274 HPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVSEY 453
HP P R L GL+ + I + + + HS YI L +I P
Sbjct: 21 HPESPLRNLAVETKLRQSGLWNDLSIEQAKPVSREIFQLIHSKGYIDQLYNISPP----- 75
Query: 454 NKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAAVKL--NKQASEICINWGGGLHHAKKS 627
K M D P+ E + +AG + A + K + C G HHA+
Sbjct: 76 -KGM--ILADPDTPLAFDTLEATEEAAGSGIQAVESILSGKHQNAFCAIRPPG-HHAEPK 131
Query: 628 EASGFCYVNDIVLGILELLKYH--QRVLYIDIDVHHGDGVEXAFYTTDRVM 774
+ GFC+VN+I L L RVL D DVH +G AF D V+
Sbjct: 132 KTKGFCFVNNIALAAQHALNQAGINRVLIFDFDVHQANGTIEAFRGRDDVV 182
>UniRef50_A6VSZ5 Cluster: Histone deacetylase superfamily; n=4;
Gammaproteobacteria|Rep: Histone deacetylase superfamily
- Marinomonas sp. MWYL1
Length = 307
Score = 55.6 bits (128), Expect = 1e-06
Identities = 46/174 (26%), Positives = 79/174 (45%), Gaps = 5/174 (2%)
Frame = +1
Query: 268 QGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVS 447
+ HP P R+ N L+ L + AT +++ H + Y+ + + P+
Sbjct: 18 EDHPESPLRLGAIQNRLIMGQLMDFLRRLESDPATREQLLLAHDEAYVDSIFARAPE--- 74
Query: 448 EYNKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAAVKL---NKQASEICINWGGGLHHA 618
E + +++ + + LY A GSV AV L ++ + C G HHA
Sbjct: 75 EGHVELEPETLMMPHTLDAALY------AAGSVIKAVDLVMTSEMDNAFCAIRPPG-HHA 127
Query: 619 KKSEASGFCYVNDIVLGILELLKYH--QRVLYIDIDVHHGDGVEXAFYTTDRVM 774
+ +A GFC N+I +G ++ + +RV +D DVHHG+G E F +V+
Sbjct: 128 EYDKAMGFCLFNNIAVGTRYAIEKYGLERVAIVDFDVHHGNGTEDIFKADPKVL 181
>UniRef50_A6Q2Z0 Cluster: Acetoin utilization protein; n=1;
Nitratiruptor sp. SB155-2|Rep: Acetoin utilization
protein - Nitratiruptor sp. (strain SB155-2)
Length = 302
Score = 55.6 bits (128), Expect = 1e-06
Identities = 38/139 (27%), Positives = 60/139 (43%), Gaps = 2/139 (1%)
Frame = +1
Query: 361 HKATADEMTKFHSDDYIRFLRSIRPDNVSEYNKQMQRFNVGEDCPVFDGLYEFCQLSAGG 540
H A+ +E+ + H Y+ D V + RF + ED + YE +AG
Sbjct: 45 HMASKEELYQIHEAHYV--------DWVEHAYENGYRFILNEDTLLTPRSYEVASFAAGS 96
Query: 541 SVAAAVKLNK-QASEICINWGGGLHHAKKSEASGFCYVNDIVLGILELLKY-HQRVLYID 714
+ + + + +N HHA++ GFC N++ K ++VL ID
Sbjct: 97 TKSIVDGFAEGKIQRAFLNLRPPAHHAERRTGQGFCIFNNVAFMARYAQKRGFEKVLIID 156
Query: 715 IDVHHGDGVEXAFYTTDRV 771
DVHHG+G + FY D V
Sbjct: 157 FDVHHGNGTQDIFYEDDTV 175
>UniRef50_A6G5J4 Cluster: Histone deacetylase superfamily protein;
n=1; Plesiocystis pacifica SIR-1|Rep: Histone
deacetylase superfamily protein - Plesiocystis pacifica
SIR-1
Length = 274
Score = 55.6 bits (128), Expect = 1e-06
Identities = 23/56 (41%), Positives = 34/56 (60%)
Frame = +1
Query: 610 HHAKKSEASGFCYVNDIVLGILELLKYHQRVLYIDIDVHHGDGVEXAFYTTDRVMT 777
HHA++ G+CY N+ + EL + RV+ +DID HHG+G + F TT V+T
Sbjct: 84 HHAEEDMFGGYCYFNNSAIAARELRQGGARVVVLDIDFHHGNGTQSLFQTTAEVLT 139
>UniRef50_A5GUP9 Cluster: Histone deacetylase family protein; n=14;
cellular organisms|Rep: Histone deacetylase family
protein - Synechococcus sp. (strain RCC307)
Length = 306
Score = 55.6 bits (128), Expect = 1e-06
Identities = 48/171 (28%), Positives = 74/171 (43%), Gaps = 3/171 (1%)
Frame = +1
Query: 274 HPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIR-FLRSIRPDNVSE 450
H + R L + GL ++ ++++P + H Y + F R E
Sbjct: 21 HRFPMAKFRQLRQCLADKGLAQEQQVHQPLPCPRRWLELVHPRRYHQAFARG-------E 73
Query: 451 YNKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAAVKLNKQASEICINWGGGLHHAKKSE 630
++Q QR +G P L + LS GG++ A +L + C + GG HHA
Sbjct: 74 LDRQAQR-RIG--LPATQPLVQRTWLSVGGTLRTA-QLALEHGMAC-HLAGGTHHAFPDY 128
Query: 631 ASGFCYVNDIVLGILELLKYH--QRVLYIDIDVHHGDGVEXAFYTTDRVMT 777
SGFC NDI + LL+ +++ +D+DVH GD F RV T
Sbjct: 129 GSGFCIFNDIAVTASVLLQQGLVNKLMVVDLDVHQGDATAAIFTGEPRVFT 179
>UniRef50_Q00UC4 Cluster: Histone deacetylase superfamily; n=2;
Ostreococcus|Rep: Histone deacetylase superfamily -
Ostreococcus tauri
Length = 351
Score = 55.6 bits (128), Expect = 1e-06
Identities = 36/127 (28%), Positives = 63/127 (49%), Gaps = 2/127 (1%)
Frame = +1
Query: 364 KATADEMTKFHSDDYIRFLRSIRPDNVSEYNKQMQRFNVGEDCPVFDGLYEFCQLSAGGS 543
+ T +E+ HS+++ R S + K+++ + P D L E + G+
Sbjct: 93 RPTFEELAAAHSEEWTRTATSSEGPDA----KRLREIGL----PWSDVLVERTLMEVSGT 144
Query: 544 VAAAVKLNKQASEICINWGGGLHHAKKSEASGFCYVNDIVLGILELLKYHQ--RVLYIDI 717
+ V++ + + +N GG HHAK + GFC +ND+ L +L + RV+ +D+
Sbjct: 145 MLT-VEMALECG-LAVNTAGGTHHAKGTRGGGFCILNDLATASLAVLNSGRLSRVMIVDL 202
Query: 718 DVHHGDG 738
DVH GDG
Sbjct: 203 DVHQGDG 209
>UniRef50_A7SSG8 Cluster: Predicted protein; n=2; Eumetazoa|Rep:
Predicted protein - Nematostella vectensis
Length = 369
Score = 55.6 bits (128), Expect = 1e-06
Identities = 49/175 (28%), Positives = 82/175 (46%), Gaps = 12/175 (6%)
Frame = +1
Query: 286 PHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVSEYNKQM 465
P RI + YGL + AT +++ HS ++I ++S ++ K
Sbjct: 33 PDRIGRPYEKHKEYGLLDRCYKIPSRHATEEDLLCLHSKEHIDKMKS------TQDMKPR 86
Query: 466 QRFNVGEDCP---VFDGLYEFCQLSAGGSVAAA--VKLNKQASE-ICINWGGGL----HH 615
FN+GE+ + +Y+ LS G ++AA V NK + I IN L HH
Sbjct: 87 DLFNLGEEYDSIYMSKDVYDCALLSCGCTLAAVEHVATNKSSKHSIHINQLFFLRPPGHH 146
Query: 616 AKKSEASGFCYVNDIVLGI-LELLKYH-QRVLYIDIDVHHGDGVEXAFYTTDRVM 774
A A G+C+ N++ + L ++ QR+L +D D+HHG+G + F + V+
Sbjct: 147 ADADSAMGYCFFNNVAIAAKLAQQRWGMQRILIVDWDIHHGNGTQNLFESDPSVL 201
>UniRef50_A0B6D0 Cluster: Histone deacetylase superfamily; n=1;
Methanosaeta thermophila PT|Rep: Histone deacetylase
superfamily - Methanosaeta thermophila (strain DSM 6194
/ PT) (Methanothrixthermophila (strain DSM 6194 / PT))
Length = 284
Score = 55.6 bits (128), Expect = 1e-06
Identities = 46/165 (27%), Positives = 75/165 (45%), Gaps = 4/165 (2%)
Frame = +1
Query: 271 GHPMKPHRIRMTHNLLLNYGLYRKMEI--YRPHKATADEMTKFHSDDYIRFLRSIRPDNV 444
G+ + RIR + + L+N GL +E+ +RP A + + + H++++++ +R
Sbjct: 18 GYSVLKDRIRPSFDALMNSGLVDGVEVQVFRPQPAPVELVAEAHTENHMQNMRH------ 71
Query: 445 SEYNKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAAVKLNKQASEICINWGGGL-HHAK 621
D + LSAG + AA + +E + G HHA
Sbjct: 72 -------------------DPHWNVALLSAGSVLMAAELVVSGKAESAFAYTGTAGHHAS 112
Query: 622 KSEASGFCYVNDIVLGILELLKYH-QRVLYIDIDVHHGDGVEXAF 753
+ GFCY ND+ + IL+L K +R L ID+D H GDG F
Sbjct: 113 RGSCWGFCYFNDVAITILKLRKMGLKRFLIIDVDPHFGDGTRDFF 157
>UniRef50_Q586J9 Cluster: Histone deacetylase, putative; n=1;
Trypanosoma brucei|Rep: Histone deacetylase, putative -
Trypanosoma brucei
Length = 685
Score = 41.9 bits (94), Expect(2) = 2e-06
Identities = 34/133 (25%), Positives = 60/133 (45%), Gaps = 3/133 (2%)
Frame = +1
Query: 283 KPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVSEYNKQ 462
+P R++ T + L GL A E+ HS ++I + + + K
Sbjct: 142 RPGRLQRTLDHLEVIGLLECCRRLHHRSARTRELRLVHSTEHIDSVDQLEVATL--LRKP 199
Query: 463 MQRFNVGEDCPVFDGLYEFCQLSAGGSVAAAVKLNK---QASEICINWGGGLHHAKKSEA 633
+ NVGED + + +AG ++AAA+ + + + S I G HHA + A
Sbjct: 200 GESCNVGEDLYANENTSRAARAAAGCAIAAALSVVRGEVRNSFALIRPPG--HHAGRDRA 257
Query: 634 SGFCYVNDIVLGI 672
SGFC+ N++ + +
Sbjct: 258 SGFCFFNNVAVAV 270
Score = 32.7 bits (71), Expect(2) = 2e-06
Identities = 15/26 (57%), Positives = 16/26 (61%)
Frame = +1
Query: 697 RVLYIDIDVHHGDGVEXAFYTTDRVM 774
RVL ID DVHH DG E FY V+
Sbjct: 307 RVLVIDWDVHHCDGTENIFYEDPSVV 332
>UniRef50_Q0G2C9 Cluster: Putative acetylpolyamine aminohydrolase;
n=1; Fulvimarina pelagi HTCC2506|Rep: Putative
acetylpolyamine aminohydrolase - Fulvimarina pelagi
HTCC2506
Length = 347
Score = 54.8 bits (126), Expect = 2e-06
Identities = 29/86 (33%), Positives = 42/86 (48%)
Frame = +1
Query: 499 FDGLYEFCQLSAGGSVAAAVKLNKQASEICINWGGGLHHAKKSEASGFCYVNDIVLGILE 678
F+ +YE +A AA + L Q + + G HHA A+GFC+ N+ +
Sbjct: 132 FEAIYESAMTAA---TAADIVLGGQPAAYALCRPPG-HHAYPDRANGFCFFNNAAIAAQR 187
Query: 679 LLKYHQRVLYIDIDVHHGDGVEXAFY 756
L + +V ID D HHGDG + FY
Sbjct: 188 LRSKYGKVAIIDFDTHHGDGTQAIFY 213
>UniRef50_Q8TWH9 Cluster: Predicted deacetylase; n=1; Methanopyrus
kandleri|Rep: Predicted deacetylase - Methanopyrus
kandleri
Length = 352
Score = 54.8 bits (126), Expect = 2e-06
Identities = 45/174 (25%), Positives = 76/174 (43%), Gaps = 7/174 (4%)
Frame = +1
Query: 274 HPMKPHRIRMTHNLLLNYGLYR--KMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVS 447
HP + R+ T + GL+ +++ P + + H +++ +R +S
Sbjct: 18 HPERRERLSYTVDRFEEEGLFEIEGIDLVEPDPVDREVIELVHDPEHVELIR-----RMS 72
Query: 448 EYNKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAA---VKLNKQASEICINWGGGLHHA 618
E M + D V Y+ L+AGGSV A V+ + + G HHA
Sbjct: 73 ESGGGM----IDLDTAVAPETYDQALLAAGGSVLAVELVVRGEYDTAFAMVRPPG--HHA 126
Query: 619 KKSEASGFCYVNDIVLGILELLKYH--QRVLYIDIDVHHGDGVEXAFYTTDRVM 774
+++A+GFCY N+ + ++ V +D D HHGDG + FY D V+
Sbjct: 127 GRAKAAGFCYFNNAAIAAEYAIRELGVDSVAILDWDAHHGDGTQEIFYDRDDVL 180
>UniRef50_Q4TFH7 Cluster: Chromosome undetermined SCAF4471, whole
genome shotgun sequence; n=1; Tetraodon
nigroviridis|Rep: Chromosome undetermined SCAF4471,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 1260
Score = 54.4 bits (125), Expect = 3e-06
Identities = 45/173 (26%), Positives = 73/173 (42%), Gaps = 6/173 (3%)
Frame = +1
Query: 274 HPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVSEY 453
HP P R+ L + GL + P +AT +E+ H+ ++ LRS + E
Sbjct: 94 HPESPERVTFIMEELQHQGLLSQCTRVEPREATEEELLLCHTKHHVDLLRSTQTMTEDEL 153
Query: 454 NKQMQRFNVGEDCPVFDGLYEFCQ-LSAGGSVAAAVKLNKQASEICINWGGGL---HHAK 621
+ +++ V+ F ++A GS+ V SE+ + HHA+
Sbjct: 154 HSLSDKYD-----SVYLHPESFTAGVTAVGSLLQLVD-RVMTSELRNGFAVVRPPGHHAQ 207
Query: 622 KSEASGFCYVNDIVLGILELLKYHQ--RVLYIDIDVHHGDGVEXAFYTTDRVM 774
K +GFC N++ + H RVL +D DVHHG G + F V+
Sbjct: 208 KDLPNGFCLFNNVAIAARYAQTRHSVSRVLIVDWDVHHGQGTQYLFQEDPSVL 260
Score = 44.8 bits (101), Expect = 0.002
Identities = 28/94 (29%), Positives = 46/94 (48%), Gaps = 6/94 (6%)
Frame = +1
Query: 511 YEFCQLSAGGSVAAAVKL--NKQASEICINWGGGLHHAKKSEASGFCYVNDIVLGILELL 684
++ L+AGG +A ++ + + + + G HHA++ GFC+ N L
Sbjct: 649 FQSALLAAGGCFSAVEQILAGQVRNAVAVVRPPG-HHAERDLPCGFCFFNTAALAARHAQ 707
Query: 685 KYHQ----RVLYIDIDVHHGDGVEXAFYTTDRVM 774
K + RVL +D DVHHG+G + F D V+
Sbjct: 708 KLSRDAPLRVLILDWDVHHGNGTQHMFEDDDSVL 741
>UniRef50_Q4T0M8 Cluster: Chromosome undetermined SCAF10929, whole
genome shotgun sequence; n=2; Tetraodontidae|Rep:
Chromosome undetermined SCAF10929, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 903
Score = 54.4 bits (125), Expect = 3e-06
Identities = 49/185 (26%), Positives = 79/185 (42%), Gaps = 18/185 (9%)
Frame = +1
Query: 274 HPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRF-----LRSIRPD 438
HP RI+ + L GL + E R KAT +E+ H++ ++ L ++ D
Sbjct: 425 HPEHAGRIQSIWSRLQERGLRGQCESIRGRKATLEELQSVHTERHVLLYGTNPLNRLKLD 484
Query: 439 NVSEYNKQMQRFNVGEDCPVF----DGLYEFCQLSAGGSVAAA--VKLNKQASEICINWG 600
N QR V C D ++ S +AA V+L + ++ + G
Sbjct: 485 NRKLAGILSQRMFVMLPCGGVGVDNDTIWNESHTSTASRMAAGSVVELAFRVAKGELKNG 544
Query: 601 GGL-----HHAKKSEASGFCYVNDIVLGILELLKYHQ--RVLYIDIDVHHGDGVEXAFYT 759
+ HHA S GFCY N + + +L ++L +D DVHHG+G + FY+
Sbjct: 545 FAVVRPPGHHADPSNPMGFCYFNSVAIAAKQLQHKLSVSKILIVDWDVHHGNGTQEVFYS 604
Query: 760 TDRVM 774
V+
Sbjct: 605 DPSVL 609
>UniRef50_Q31EP6 Cluster: Histone deacetylase family protein
precursor; n=1; Thiomicrospira crunogena XCL-2|Rep:
Histone deacetylase family protein precursor -
Thiomicrospira crunogena (strain XCL-2)
Length = 379
Score = 54.4 bits (125), Expect = 3e-06
Identities = 43/165 (26%), Positives = 76/165 (46%), Gaps = 7/165 (4%)
Frame = +1
Query: 271 GHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVSE 450
GHP R+ +N + G++ ++ AT +E+ H+ YI + I D+
Sbjct: 53 GHPENAQRLVAINNEMEKQGIWPQLTPVATRLATNEELLLAHTQSYIDEIE-ILSDSGGG 111
Query: 451 YNKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAAVKLNKQASEICINWGGGL-----HH 615
+ + Q D + ++ +++AG ++ LN + I+ G L HH
Sbjct: 112 FYEPYQG-----DTYLNASSFDAAKMAAGSNI----NLNLAIYDRKIDHGFALLRPPGHH 162
Query: 616 AKKSEASGFCYVNDIVLGILELLKYH--QRVLYIDIDVHHGDGVE 744
A +++A GFC N ++ L KY +R+ ID DVHHG+G +
Sbjct: 163 ALQNKAMGFCIFNSDIIAARALQKYRGVKRIAIIDFDVHHGNGTQ 207
>UniRef50_A7HL59 Cluster: Histone deacetylase superfamily; n=1;
Fervidobacterium nodosum Rt17-B1|Rep: Histone
deacetylase superfamily - Fervidobacterium nodosum
Rt17-B1
Length = 325
Score = 54.4 bits (125), Expect = 3e-06
Identities = 41/173 (23%), Positives = 80/173 (46%), Gaps = 6/173 (3%)
Frame = +1
Query: 274 HPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVSEY 453
+P +P R+++ + L Y +++ P + + H +DYI +++ + EY
Sbjct: 32 NPERPSRLKLVYEFLKKN--YPEVQ---PLGFSESVLYLAHEEDYIEYIKRKSSEVTQEY 86
Query: 454 NKQM----QRFNVGEDCPVFDGLYEFCQLSAGGSVAAAVK--LNKQASEICINWGGGLHH 615
++ + F+ G P+ Y+ A +V +A++ L+ + + G HH
Sbjct: 87 IPEVFFVDKIFDTGT--PINKETYK-AAFGAVETVLSALEYSLSNKVIVYALTRPPG-HH 142
Query: 616 AKKSEASGFCYVNDIVLGILELLKYHQRVLYIDIDVHHGDGVEXAFYTTDRVM 774
A K G+CY N++ + L + RV +D+D HHG+G + FY V+
Sbjct: 143 AMKKYGGGYCYFNNVAIAAKYLEEKGMRVAILDLDFHHGNGTQDIFYDDPNVL 195
>UniRef50_A6T202 Cluster: Histone deacetylase superfamily protein;
n=1; Janthinobacterium sp. Marseille|Rep: Histone
deacetylase superfamily protein - Janthinobacterium sp.
(strain Marseille) (Minibacterium massiliensis)
Length = 322
Score = 54.4 bits (125), Expect = 3e-06
Identities = 43/165 (26%), Positives = 70/165 (42%), Gaps = 4/165 (2%)
Frame = +1
Query: 274 HPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVSEY 453
HP P R++ L + +E T +++ H++D++ + P
Sbjct: 32 HPESPERLKAVLRAL-RVPEFDAVEWRDAPMGTREQVLLIHTEDFVTDVEDASP------ 84
Query: 454 NKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAA-VKLNKQASEI-CINWGGGLHHAKKS 627
++ + G D + G E G + A + L+ +A + C G HHA+ S
Sbjct: 85 HRGYMPLD-GGDTVMSPGSLEAVMRCVGAACAGVDLVLDNEAHNVFCATRPCG-HHAEPS 142
Query: 628 EASGFCYVNDIVLGILELLKYH--QRVLYIDIDVHHGDGVEXAFY 756
A GFC N + + H +RV ID DVHHG+G + AFY
Sbjct: 143 RAMGFCIYNQAAIAAAYAYEVHKLERVAVIDFDVHHGNGTQAAFY 187
>UniRef50_Q944K3 Cluster: Histone deacetylase 2; n=7;
Magnoliophyta|Rep: Histone deacetylase 2 - Arabidopsis
thaliana (Mouse-ear cress)
Length = 387
Score = 54.4 bits (125), Expect = 3e-06
Identities = 50/169 (29%), Positives = 73/169 (43%), Gaps = 3/169 (1%)
Frame = +1
Query: 274 HPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRP-DNVSE 450
HP + L++ G + I P +A+ ++ HS++Y+ L+S ++E
Sbjct: 93 HPFDSSKWGRVCKFLVSDGFLEEKAIVEPLEASKIDLLVVHSENYLNSLKSSATVARITE 152
Query: 451 YNKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAAVKLNKQASEICINWGGGLHHAKKSE 630
N V LY F + GG++ AA KL + IN GGG HH
Sbjct: 153 VAPVAFFPNFLVQQKV---LYPF-RKQVGGTILAA-KLATERGW-AINIGGGFHHCTAER 206
Query: 631 ASGFCYVNDIVLGI-LELLKYH-QRVLYIDIDVHHGDGVEXAFYTTDRV 771
GFC DI L I L+ RV+ ID+D H G+G E +RV
Sbjct: 207 GGGFCAFADISLCIHFAFLRLRISRVMIIDLDAHQGNGHETDLGDDNRV 255
>UniRef50_Q8LRK8 Cluster: Histone deacetylase 18; n=1; Arabidopsis
thaliana|Rep: Histone deacetylase 18 - Arabidopsis
thaliana (Mouse-ear cress)
Length = 682
Score = 54.4 bits (125), Expect = 3e-06
Identities = 45/171 (26%), Positives = 76/171 (44%), Gaps = 8/171 (4%)
Frame = +1
Query: 286 PHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNV-SEYNKQ 462
P RIR+ L G+ ++ + KA + H+ ++ ++SI S NK
Sbjct: 83 PDRIRVIWEKLQLAGVTQRCVVLGGSKAEDKHLKLVHTKKHVNLVKSISTKKKDSRRNKI 142
Query: 463 MQRFNVGEDCPVFDGLYEFCQLSAGGSVAAAVKLNKQASE--ICINWGGGLHHAKKSEAS 636
+ + + G E L+AG V A K+ + + I G HHA+ EA
Sbjct: 143 ASQL---DSIYLNGGSSEAAYLAAGSVVKVAEKVAEGELDCGFAIVRPPG-HHAESDEAM 198
Query: 637 GFCYVNDIVLGILELLKYH-----QRVLYIDIDVHHGDGVEXAFYTTDRVM 774
GFC N++ + LL +++L +D D+HHG+G + F+ RV+
Sbjct: 199 GFCLFNNVAVAASFLLNERPDLDVKKILIVDWDIHHGNGTQKMFWKDSRVL 249
>UniRef50_Q969S8 Cluster: Histone deacetylase 10; n=20;
Euteleostomi|Rep: Histone deacetylase 10 - Homo sapiens
(Human)
Length = 669
Score = 54.4 bits (125), Expect = 3e-06
Identities = 38/161 (23%), Positives = 72/161 (44%), Gaps = 4/161 (2%)
Frame = +1
Query: 283 KPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVSEYNKQ 462
+P R+ + L GL ++ +A+ +E+ HS +Y+ +R + E
Sbjct: 27 RPERLTAALDRLRQRGLEQRCLRLSAREASEEELGLVHSPEYVSLVRETQVLGKEELQAL 86
Query: 463 MQRFNVGEDCPVFDGLYEFCQLSAGGSVAA--AVKLNKQASEICINWGGGLHHAKKSEAS 636
+F+ P + +L+AG + AV + + + G HH +++ A+
Sbjct: 87 SGQFDAIYFHP---STFHCARLAAGAGLQLVDAVLTGAVQNGLALVRPPG-HHGQRAAAN 142
Query: 637 GFCYVNDIVLGILELLKYH--QRVLYIDIDVHHGDGVEXAF 753
GFC N++ + + H R+L +D DVHHG G++ F
Sbjct: 143 GFCVFNNVAIAAAHAKQKHGLHRILVVDWDVHHGQGIQYLF 183
>UniRef50_A0G5H0 Cluster: Histone deacetylase superfamily; n=9;
Proteobacteria|Rep: Histone deacetylase superfamily -
Burkholderia phymatum STM815
Length = 315
Score = 54.0 bits (124), Expect = 4e-06
Identities = 32/96 (33%), Positives = 45/96 (46%), Gaps = 4/96 (4%)
Frame = +1
Query: 481 GEDCPVFDGLYEFCQLSAGGSVAA--AVKLNKQASEICINWGGGLHHAKKSEASGFCYVN 654
G D + G +E G + A AV + + C G HHA+ S+A GFC N
Sbjct: 82 GGDTVMSPGSWEAVMRCVGAACAGVDAVLAGEARNVFCATRPCG-HHAEPSKAMGFCIFN 140
Query: 655 DIVLGILELLKYH--QRVLYIDIDVHHGDGVEXAFY 756
+ + H +RV +D DVHHG+G + AFY
Sbjct: 141 QAAIAAAYAYEVHKLERVAVVDFDVHHGNGTQAAFY 176
>UniRef50_Q8WUI4 Cluster: Histone deacetylase 7a; n=41; Tetrapoda|Rep:
Histone deacetylase 7a - Homo sapiens (Human)
Length = 952
Score = 54.0 bits (124), Expect = 4e-06
Identities = 51/186 (27%), Positives = 81/186 (43%), Gaps = 19/186 (10%)
Frame = +1
Query: 274 HPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRF-----LRSIRPD 438
HP RI+ + L GL + E R KA+ +E+ HS+ ++ L ++ D
Sbjct: 541 HPEHAGRIQSIWSRLQERGLRSQCECLRGRKASLEELQSVHSERHVLLYGTNPLSRLKLD 600
Query: 439 NVSEYNKQMQRF-------NVGEDCP-VFDGLYEFCQLS-AGGSV---AAAVKLNKQASE 582
N QR VG D +++ L+ A GSV A V + +
Sbjct: 601 NGKLAGLLAQRMFVMLPCGGVGVDTDTIWNELHSSNAARWAAGSVTDLAFKVASRELKNG 660
Query: 583 ICINWGGGLHHAKKSEASGFCYVNDIVLGILELLKYHQ--RVLYIDIDVHHGDGVEXAFY 756
+ G HHA S A GFC+ N + + +L + + ++L +D DVHHG+G + FY
Sbjct: 661 FAVVRPPG-HHADHSTAMGFCFFNSVAIACRQLQQQSKASKILIVDWDVHHGNGTQQTFY 719
Query: 757 TTDRVM 774
V+
Sbjct: 720 QDPSVL 725
>UniRef50_Q20296 Cluster: Histone deacetylase 6; n=4;
Caenorhabditis|Rep: Histone deacetylase 6 -
Caenorhabditis elegans
Length = 955
Score = 54.0 bits (124), Expect = 4e-06
Identities = 46/175 (26%), Positives = 78/175 (44%), Gaps = 8/175 (4%)
Frame = +1
Query: 274 HPMKPHRIRMTHNLLLNYGLYRKMEIYRPHK-ATADEMTKFHSDDYIRFLRSIRPDNVSE 450
HP KP R R L G+ K + AT +E+ H+ + LR+ E
Sbjct: 446 HPEKPARTRRILKTLRESGVLEKCVDRNCERIATNEEIRLVHTKKMLEHLRTTETMKDEE 505
Query: 451 YNKQMQR-FNVGEDCPVFDGLYEFCQLSAGGSVAAAVKLNK----QASEICINWGGGLHH 615
++ ++ FN + + + + G + + ++ + Q + + I G HH
Sbjct: 506 LMEEAEKEFN---SIYLTRDTLKVARKAVGAVLQSVDEIFEKDAGQRNALVIVRPPG-HH 561
Query: 616 AKKSEASGFCYVNDIVLGILELLKYHQ--RVLYIDIDVHHGDGVEXAFYTTDRVM 774
A S++SGFC N++ + + H+ RVL +D DVHHG+G + FY VM
Sbjct: 562 ASASKSSGFCIFNNVAVAAKYAQRRHKAKRVLILDWDVHHGNGTQEIFYEDSNVM 616
Score = 48.0 bits (109), Expect = 3e-04
Identities = 21/56 (37%), Positives = 29/56 (51%), Gaps = 1/56 (1%)
Frame = +1
Query: 610 HHAKKSEASGFCYVNDIVLGILE-LLKYHQRVLYIDIDVHHGDGVEXAFYTTDRVM 774
HHA GFC N++ E +R+L +D+DVHHG G + FY RV+
Sbjct: 145 HHADSVSPCGFCLFNNVAQAAEEAFFSGAERILIVDLDVHHGHGTQRIFYDDKRVL 200
>UniRef50_Q4RSK1 Cluster: Chromosome 13 SCAF15000, whole genome
shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 13
SCAF15000, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 411
Score = 53.6 bits (123), Expect = 5e-06
Identities = 43/163 (26%), Positives = 74/163 (45%), Gaps = 7/163 (4%)
Frame = +1
Query: 286 PHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVSEYNKQM 465
P R+++ L GL + +AT ++ HS++Y+ ++ + + +
Sbjct: 28 PERLKVCAEALKRTGLADRCVSVPVREATDADILLAHSEEYLEAVKKTPYMTLGDLMEFT 87
Query: 466 QRFNVGEDCPVFDGLYEFCQLSAGGSVAAAVKLNKQASEICINWGGGL-----HHAKKSE 630
++ D +Y +L+AG AA++L + G L HH+ +S
Sbjct: 88 LQYG---DVYFHPNIYHCAKLAAG----AALQLVDSVMTGAVRNGMALVRPPGHHSMRSA 140
Query: 631 ASGFCYVNDIVLGI-LELLKYH-QRVLYIDIDVHHGDGVEXAF 753
A+GFC N++ + KY QRVL +D DVHHG GV+ F
Sbjct: 141 ANGFCVFNNVAIAARYAKQKYSLQRVLIVDWDVHHGQGVQYCF 183
>UniRef50_Q604Q2 Cluster: Histone deacetylase/AcuC/AphA family
protein; n=29; Proteobacteria|Rep: Histone
deacetylase/AcuC/AphA family protein - Methylococcus
capsulatus
Length = 310
Score = 53.6 bits (123), Expect = 5e-06
Identities = 33/88 (37%), Positives = 46/88 (52%), Gaps = 5/88 (5%)
Frame = +1
Query: 526 LSAGGSVAAAVK--LNKQA-SEICINWGGGLHHAKKSEASGFCYVNDIVLGILELLKYH- 693
L A G+V AV + K+A + C G HHA+ A GFC N+I + L H
Sbjct: 94 LHAVGAVCLAVDEVIGKRARNAFCAVRPPG-HHAEPDAAMGFCLFNNIAIAAAHALANHG 152
Query: 694 -QRVLYIDIDVHHGDGVEXAFYTTDRVM 774
QR+ +D DVHHG+G + AF +V+
Sbjct: 153 LQRIAIVDFDVHHGNGTQAAFRRNPQVL 180
>UniRef50_Q9VC26 Cluster: CG31119-PA; n=5; Diptera|Rep: CG31119-PA -
Drosophila melanogaster (Fruit fly)
Length = 343
Score = 53.6 bits (123), Expect = 5e-06
Identities = 45/165 (27%), Positives = 70/165 (42%), Gaps = 5/165 (3%)
Frame = +1
Query: 274 HPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLR-SIRPDNVSE 450
HP + + H LL Y P + T D++ + H+ +Y++ LR S+ ++E
Sbjct: 51 HPFDAAKGKHIHKLLCAQLQLDDGSFYEPTELTKDQLRRIHTREYLKSLRWSMNVACIAE 110
Query: 451 YNKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAAVKLNKQASEICINWGGGLHHAKKSE 630
+ F + + A GS+ A KL IN GGG HH
Sbjct: 111 V--PLMAFVPNRY--IQRSYLRPMRFQAAGSILAG-KLALDYGW-AINLGGGFHHCCSYR 164
Query: 631 ASGFCYVNDIVLGILELLKYH----QRVLYIDIDVHHGDGVEXAF 753
GFC DI L I+ L + +R++ +D+D H G+G E F
Sbjct: 165 GGGFCPYADISLLIVRLFEQEPFRVRRIMIVDLDAHQGNGHERDF 209
>UniRef50_Q569C4 Cluster: Histone deacetylase 10; n=5; Mammalia|Rep:
Histone deacetylase 10 - Rattus norvegicus (Rat)
Length = 588
Score = 53.6 bits (123), Expect = 5e-06
Identities = 37/160 (23%), Positives = 77/160 (48%), Gaps = 4/160 (2%)
Frame = +1
Query: 286 PHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVSEYNKQM 465
P R+ + L GL + + +A+ +E+ HS +YI ++ + + E +
Sbjct: 28 PERLTAALDGLRQRGLEERCQCLSVCEASEEELGLVHSPEYIALVQKTQTLDKEELHTLS 87
Query: 466 QRFNVGEDCPVFDGLYEFCQLSAGGSVAA--AVKLNKQASEICINWGGGLHHAKKSEASG 639
++++ P + +L+AG ++ AV + + + G HH++++ A+G
Sbjct: 88 KQYDAVYFHP---DTFHCARLAAGAALRLVDAVLTGAVHNGVALVRPPG-HHSQRAAANG 143
Query: 640 FCYVNDIVLGILELLKYH--QRVLYIDIDVHHGDGVEXAF 753
FC N++ + + + QR+L +D DVHHG G++ F
Sbjct: 144 FCVFNNVAIAARHAKQKYGLQRILIVDWDVHHGQGIQYIF 183
>UniRef50_O67877 Cluster: Acetoin utilization protein; n=3;
Bacteria|Rep: Acetoin utilization protein - Aquifex
aeolicus
Length = 310
Score = 53.2 bits (122), Expect = 7e-06
Identities = 23/56 (41%), Positives = 34/56 (60%), Gaps = 2/56 (3%)
Frame = +1
Query: 610 HHAKKSEASGFCYVNDIVLGI--LELLKYHQRVLYIDIDVHHGDGVEXAFYTTDRV 771
HHA+ ++A GFC N++ +G L +K +V ID D HHG+G + +FY D V
Sbjct: 124 HHAEYAKAMGFCIFNNVAIGAHYLRKIKGVNKVFIIDFDAHHGNGTQKSFYEDDTV 179
>UniRef50_A6GQW9 Cluster: Histone deacetylase family protein; n=1;
Limnobacter sp. MED105|Rep: Histone deacetylase family
protein - Limnobacter sp. MED105
Length = 306
Score = 53.2 bits (122), Expect = 7e-06
Identities = 41/172 (23%), Positives = 74/172 (43%), Gaps = 4/172 (2%)
Frame = +1
Query: 271 GHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVSE 450
GHP R+R+ L + L+ ++ + +T H+ Y+ +++ P
Sbjct: 19 GHPESMARLRVIREKLESSELWPRLVHCEAPEVAWSAVTAVHNPAYVESIKARFP----- 73
Query: 451 YNKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAA--VKLNKQASEICINWGGGLHHAKK 624
+ ++ D + + + + +AG V A V + + C G HHA
Sbjct: 74 ---LKRNIDIDGDTTLSEFSLDAARRAAGACVHAVDLVMAHAVNNAFCAVRPPG-HHACV 129
Query: 625 SEASGFCYVNDIVLGILELLKYH--QRVLYIDIDVHHGDGVEXAFYTTDRVM 774
A GFC N++ + + + +RVL +D DVHHG+G E AF +V+
Sbjct: 130 DRAMGFCVFNNVAIAAQHAIDAYRLERVLIVDFDVHHGNGTEHAFANNPKVL 181
>UniRef50_Q9UQL6 Cluster: Histone deacetylase 5; n=141; Eumetazoa|Rep:
Histone deacetylase 5 - Homo sapiens (Human)
Length = 1122
Score = 53.2 bits (122), Expect = 7e-06
Identities = 52/186 (27%), Positives = 83/186 (44%), Gaps = 19/186 (10%)
Frame = +1
Query: 274 HPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVSEY 453
HP RI+ + L GL K E R KAT DE+ HS+ Y L P N +
Sbjct: 704 HPEHAGRIQSIWSRLQETGLLSKCERIRGRKATLDEIQTVHSE-YHTLLYGTSPLNRQKL 762
Query: 454 NKQM------QRFNVGEDCPVF--DGLYEFCQLSAGGSVAAAVK-LNKQASEIC---INW 597
+ + Q+ C D + ++ + +V AV L + A ++ +
Sbjct: 763 DSKKLLGPISQKMYAVLPCGGIGVDSDTVWNEMHSSSAVRMAVGCLLELAFKVAAGELKN 822
Query: 598 GGGL-----HHAKKSEASGFCYVNDIVLG--ILELLKYHQRVLYIDIDVHHGDGVEXAFY 756
G + HHA++S A GFC+ N + + +L+ +VL +D D+HHG+G + AFY
Sbjct: 823 GFAIIRPPGHHAEESTAMGFCFFNSVAITAKLLQQKLNVGKVLIVDWDIHHGNGTQQAFY 882
Query: 757 TTDRVM 774
V+
Sbjct: 883 NDPSVL 888
>UniRef50_Q8EFZ9 Cluster: Histone deacetylase/AcuC/AphA family
protein; n=10; Proteobacteria|Rep: Histone
deacetylase/AcuC/AphA family protein - Shewanella
oneidensis
Length = 304
Score = 52.8 bits (121), Expect = 9e-06
Identities = 43/148 (29%), Positives = 70/148 (47%), Gaps = 4/148 (2%)
Frame = +1
Query: 307 HNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYI-RFLRSIRPDNVSEYNKQMQRFNVG 483
+ LL+ L + + P TA+E+ + H DY+ +F+ + ++R
Sbjct: 30 YQYLLDNQLATPTQFHTPTPMTAEEIMQVHHRDYVEQFIDGTLATSA------LRRIGF- 82
Query: 484 EDCPVFDGLYEFCQLS-AGGSVAAAVKLNKQASEICINWGGGLHHAKKSEASGFCYVNDI 660
P + L E S AG S+ AA+ L + I ++ GG HHA SG+C ND+
Sbjct: 83 ---PWSEALVERTLHSLAGTSLTAALALQ---TGIALHLTGGYHHAHYEFGSGYCIFNDL 136
Query: 661 VLGILELLKYHQ--RVLYIDIDVHHGDG 738
++ +L+ Q ++L D DVH GDG
Sbjct: 137 IIAARKLIIEQQLHKILIFDCDVHQGDG 164
>UniRef50_A6C2D6 Cluster: Deacetylase; n=1; Planctomyces maris DSM
8797|Rep: Deacetylase - Planctomyces maris DSM 8797
Length = 319
Score = 52.8 bits (121), Expect = 9e-06
Identities = 23/67 (34%), Positives = 35/67 (52%), Gaps = 5/67 (7%)
Frame = +1
Query: 583 ICINWGGGLHHAKKSEASGFCYVNDIVLGIL-----ELLKYHQRVLYIDIDVHHGDGVEX 747
+ IN GG HH+K ++ GFC D + + L+ R++Y+D D H G+GV
Sbjct: 121 LAINLSGGYHHSKPAQGEGFCVYADAAIAVATLRQQALISETDRIVYVDTDAHQGNGVSH 180
Query: 748 AFYTTDR 768
AF +R
Sbjct: 181 AFMNDNR 187
>UniRef50_A5UY48 Cluster: Histone deacetylase superfamily; n=4;
Chloroflexaceae|Rep: Histone deacetylase superfamily -
Roseiflexus sp. RS-1
Length = 344
Score = 52.8 bits (121), Expect = 9e-06
Identities = 22/56 (39%), Positives = 33/56 (58%), Gaps = 2/56 (3%)
Frame = +1
Query: 610 HHAKKSEASGFCYVNDIVLGILELLKYH--QRVLYIDIDVHHGDGVEXAFYTTDRV 771
HHA ++E+ GFC N++ + + + RV +D DVHHG+G + FY DRV
Sbjct: 123 HHATRAESMGFCLFNNVAIAARHAIDHLGVTRVAIVDFDVHHGNGTQDIFYDDDRV 178
>UniRef50_Q8WZR5 Cluster: Related to histone deacetylase A; n=4;
Sordariomycetes|Rep: Related to histone deacetylase A -
Neurospora crassa
Length = 747
Score = 52.8 bits (121), Expect = 9e-06
Identities = 34/143 (23%), Positives = 66/143 (46%), Gaps = 7/143 (4%)
Frame = +1
Query: 367 ATADEMTKFHSDDYIRFLRSIRPDNVSEYNKQMQRFNVGEDCPVFDGL-YEFCQLSAGGS 543
AT +E+ H ++ R++ + SE + + G D + +E +SAGG+
Sbjct: 142 ATKEEICIVHHPEHFRWVEDLSRKPTSELRRLSTIMDQGRDSLYVGSMTFEAALISAGGA 201
Query: 544 VAA--AVKLNKQASEICINWGGGLHHAKKSEASGFCYVNDIVLGI----LELLKYHQRVL 705
+ +V + + + G HHA+ GFC N++ + E + +++L
Sbjct: 202 IETCKSVVVGNVKNAFAVIRPPG-HHAEFDAPMGFCLFNNVPIAAKICQTEYPEICRKIL 260
Query: 706 YIDIDVHHGDGVEXAFYTTDRVM 774
+D DVHHG+G++ FY ++
Sbjct: 261 ILDWDVHHGNGIQNMFYDDPNIL 283
>UniRef50_UPI000065F55A Cluster: Histone deacetylase 7a (HD7a).;
n=1; Takifugu rubripes|Rep: Histone deacetylase 7a
(HD7a). - Takifugu rubripes
Length = 752
Score = 52.4 bits (120), Expect = 1e-05
Identities = 47/185 (25%), Positives = 79/185 (42%), Gaps = 18/185 (9%)
Frame = +1
Query: 274 HPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRF-----LRSIRPD 438
HP R++ + L GL + E R KAT +E+ HS+ ++ L ++ D
Sbjct: 314 HPEHAGRVQSIWSRLHERGLRGQCERIRSRKATLEELQSVHSEKHVLVFGTNPLNRLKLD 373
Query: 439 NVSEYNKQMQRFNVGEDCPV----FDGLYEFCQLSAGGSVAAA--VKLNKQASEICINWG 600
N QR V C D ++ S +AA L + ++ + G
Sbjct: 374 NRKLAGILSQRTFVMLPCGGVGVDIDTVWNEHHTSTASRIAAGCVTDLALKVAQGELKNG 433
Query: 601 GGL-----HHAKKSEASGFCYVNDIVLGILELLKYHQ--RVLYIDIDVHHGDGVEXAFYT 759
+ HHA S GFC+ N + + +L + ++L +D D+HHG+G + AFY+
Sbjct: 434 FAVVRPPGHHATHSSPLGFCFFNSVAIAAKQLQQRLNVSKILIVDWDIHHGNGTQEAFYS 493
Query: 760 TDRVM 774
V+
Sbjct: 494 DPSVL 498
>UniRef50_A1G0Y5 Cluster: Histone deacetylase superfamily precursor;
n=1; Stenotrophomonas maltophilia R551-3|Rep: Histone
deacetylase superfamily precursor - Stenotrophomonas
maltophilia R551-3
Length = 312
Score = 52.4 bits (120), Expect = 1e-05
Identities = 32/85 (37%), Positives = 42/85 (49%), Gaps = 4/85 (4%)
Frame = +1
Query: 529 SAGGSVAA--AVKLNKQASEICINWGGGLHHAKKSEASGFCYVNDIVLGILELLKYH--Q 696
+AG VAA AV L + C G HHA S A GFC +N+I + H +
Sbjct: 93 AAGAGVAAVDAVMLGEDPLAFCAVRPPG-HHATSSTAMGFCLLNNIAIAAAYARDRHGLE 151
Query: 697 RVLYIDIDVHHGDGVEXAFYTTDRV 771
R+ +D DVHHG+G + F RV
Sbjct: 152 RIAVVDFDVHHGNGTQDIFQHDARV 176
>UniRef50_O17323 Cluster: Histone deacetylase 4; n=3;
Caenorhabditis|Rep: Histone deacetylase 4 -
Caenorhabditis elegans
Length = 816
Score = 52.4 bits (120), Expect = 1e-05
Identities = 46/181 (25%), Positives = 82/181 (45%), Gaps = 20/181 (11%)
Frame = +1
Query: 292 RIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPD---NVSEYNKQ 462
RI+ + L+ +G +K E KA+ +++ HS Y F ++ P + +
Sbjct: 436 RIQSIWSKLIEHGHVQKCEKVTAKKASLEQLQLVHSQTYTTFF-AVSPTACLKIDANSLP 494
Query: 463 MQRF------NVGEDCPVFDGLYEFCQLSAGGSVAAAVKLNKQASE-------ICINWGG 603
++RF +G D + Q +A + ++L+ Q +E CI G
Sbjct: 495 LKRFLQLPCGGIGVDSDTYFNDAS-TQTAARLAAGTLIELSSQVAEGRLKNGFACIRPPG 553
Query: 604 GLHHAKKSEASGFCYVNDIVLGILEL-LKYH---QRVLYIDIDVHHGDGVEXAFYTTDRV 771
HHA+ +A GFC+ N++ + + L KY ++ ID DVHHG+G + +F V
Sbjct: 554 --HHAEHEQAMGFCFFNNVAVAVKVLQTKYPAQCAKIAIIDWDVHHGNGTQLSFENDPNV 611
Query: 772 M 774
+
Sbjct: 612 L 612
>UniRef50_UPI0000E87DA7 Cluster: histone deacetylase family protein;
n=1; Methylophilales bacterium HTCC2181|Rep: histone
deacetylase family protein - Methylophilales bacterium
HTCC2181
Length = 346
Score = 52.0 bits (119), Expect = 2e-05
Identities = 47/169 (27%), Positives = 70/169 (41%), Gaps = 7/169 (4%)
Frame = +1
Query: 271 GHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKF-HSDDYI-RFLRSIRPDNV 444
GHP P RI + + N L K I+ K +D + H+ YI + + I
Sbjct: 45 GHPETPRRIESAYTAIKNDKLLTKHLIWPSIKEVSDTTLQLVHTKKYIDQIAKEISTLKA 104
Query: 445 SEYNKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAAVK---LNKQASEICINWGGGLHH 615
+E + G+ V + A GSV V N +S + G HH
Sbjct: 105 TE----TAYLSTGD--VVISRNSDMAARVAVGSVIEGVNQIMTNVASSAFALVRPPG-HH 157
Query: 616 AKKSEASGFCYVNDIVLGILELLKYH--QRVLYIDIDVHHGDGVEXAFY 756
A + GFC N+I + L + +R+L +D DVHHG+G + FY
Sbjct: 158 ASSDKGMGFCIYNNIAIAARYLQQQFGLERILIVDFDVHHGNGTQDIFY 206
>UniRef50_Q0YKV4 Cluster: Histone deacetylase superfamily; n=1;
Geobacter sp. FRC-32|Rep: Histone deacetylase
superfamily - Geobacter sp. FRC-32
Length = 370
Score = 52.0 bits (119), Expect = 2e-05
Identities = 24/57 (42%), Positives = 33/57 (57%), Gaps = 3/57 (5%)
Frame = +1
Query: 610 HHAKKSEASGFCYVNDIVLGILELLKYHQ---RVLYIDIDVHHGDGVEXAFYTTDRV 771
HHA + A GFC+VN I L I E ++ Q L +D DVHHG+G++ +Y V
Sbjct: 172 HHAGRKSAEGFCFVNHIALAI-ETIRQRQPAANFLVVDFDVHHGNGIDYIYYNDPTV 227
>UniRef50_A4C9H1 Cluster: Putative histone deacetylase family
protein; n=2; Pseudoalteromonas|Rep: Putative histone
deacetylase family protein - Pseudoalteromonas tunicata
D2
Length = 302
Score = 52.0 bits (119), Expect = 2e-05
Identities = 40/137 (29%), Positives = 60/137 (43%), Gaps = 2/137 (1%)
Frame = +1
Query: 334 YRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVSEYNKQMQRFNVGEDCPVFDGLY 513
Y I++P +A+ E+ K H R+L + + + + K +R + P + L
Sbjct: 42 YVNHNIFKPLRASISELEKVHCS---RYLHQLNQNTLDQ--KASRRIGL----PWSEQLM 92
Query: 514 EFCQLSAGGSVAAAVKLNKQASEICINWGGGLHHAKKSEASGFCYVNDIVLGILELLKYH 693
+ A G++ A K I + GG HHA SGFC VND+ L+
Sbjct: 93 ARTFIEAQGTLLTAQLALKNG--IACHLAGGTHHAHYDFGSGFCMVNDLAYTAASLIDSG 150
Query: 694 Q--RVLYIDIDVHHGDG 738
VL D+DVH GDG
Sbjct: 151 DVTNVLIFDLDVHQGDG 167
>UniRef50_UPI000051A1DA Cluster: PREDICTED: similar to HDAC4
CG1770-PB, isoform B; n=2; Apocrita|Rep: PREDICTED:
similar to HDAC4 CG1770-PB, isoform B - Apis mellifera
Length = 1048
Score = 51.6 bits (118), Expect = 2e-05
Identities = 22/57 (38%), Positives = 36/57 (63%), Gaps = 2/57 (3%)
Frame = +1
Query: 610 HHAKKSEASGFCYVNDIVLG--ILELLKYHQRVLYIDIDVHHGDGVEXAFYTTDRVM 774
HHA+ ++A GFC+ N I + +L+ +++L +D DVHHG+G + FY RV+
Sbjct: 759 HHAETNQAMGFCFFNSIAIAARLLQQKLDIRKILILDWDVHHGNGTQQMFYDDPRVL 815
>UniRef50_A1ID65 Cluster: Histone deacetylase family protein; n=1;
Candidatus Desulfococcus oleovorans Hxd3|Rep: Histone
deacetylase family protein - Candidatus Desulfococcus
oleovorans Hxd3
Length = 345
Score = 51.6 bits (118), Expect = 2e-05
Identities = 38/164 (23%), Positives = 71/164 (43%), Gaps = 3/164 (1%)
Frame = +1
Query: 274 HPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVSEY 453
HP P R+ + ++ + + P AT D++ H+ +++ + ++
Sbjct: 22 HPESPSRLASIYRMVDRH-FAGTVTTMTPEPATLDQLELVHTPGHVKKILKTAEHKIT-- 78
Query: 454 NKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAAVKLNKQASEICINWGGGL-HHAKKSE 630
++ D PV Y L+AG + L A + HHA
Sbjct: 79 -------SMAPDTPVSGHSYLAAWLAAGACMQGVDLLLSGACRAFFSLVRPPGHHALPDR 131
Query: 631 ASGFCYVNDIVLGI-LELLKYH-QRVLYIDIDVHHGDGVEXAFY 756
A+GFC +N++ + ++Y+ +R+L +D DVHHG+G+ FY
Sbjct: 132 ATGFCLLNNLAIAARYARMRYNLERILIVDWDVHHGNGIHDIFY 175
>UniRef50_A0LGT0 Cluster: Histone deacetylase superfamily; n=1;
Syntrophobacter fumaroxidans MPOB|Rep: Histone
deacetylase superfamily - Syntrophobacter fumaroxidans
(strain DSM 10017 / MPOB)
Length = 316
Score = 51.6 bits (118), Expect = 2e-05
Identities = 42/165 (25%), Positives = 71/165 (43%), Gaps = 5/165 (3%)
Frame = +1
Query: 274 HPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVSEY 453
HP P R+ + + GL+ ++ + + A + HS +I + E+
Sbjct: 21 HPESPERLEAVYRGVEEAGLFPRLTLIKASPAKLKWIEAVHSPKHIMRFEEACLLEMGEF 80
Query: 454 NKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAAVKLNKQA---SEICINWGGGLHHAKK 624
+ D + YE L+ GG + AV++ + + C G HHA+
Sbjct: 81 DHP--------DNQMCRESYETALLAVGG-LLEAVRMVMEGIIDNAFCAVRPPG-HHAEM 130
Query: 625 SEASGFCYVNDIVLGILELLKYH--QRVLYIDIDVHHGDGVEXAF 753
+ A GFCY N++ + LL +RV +DID HHG+G + F
Sbjct: 131 NRALGFCYFNNVAIAARYLLNEWGVERVGIVDIDAHHGNGTQHIF 175
>UniRef50_Q6KAT4 Cluster: MFLJ00062 protein; n=6; Eutheria|Rep:
MFLJ00062 protein - Mus musculus (Mouse)
Length = 852
Score = 51.2 bits (117), Expect = 3e-05
Identities = 21/57 (36%), Positives = 34/57 (59%), Gaps = 2/57 (3%)
Frame = +1
Query: 610 HHAKKSEASGFCYVNDIVLGILELLKYHQ--RVLYIDIDVHHGDGVEXAFYTTDRVM 774
HHA S A GFC+ N + + +L ++ + ++L +D DVHHG+G + FY V+
Sbjct: 570 HHADHSTAMGFCFFNSVAIACRQLQQHGKASKILIVDWDVHHGNGTQQTFYQDPSVL 626
>UniRef50_A0KLZ2 Cluster: Histone deacetylase/AcuC/AphA family
protein; n=3; Gammaproteobacteria|Rep: Histone
deacetylase/AcuC/AphA family protein - Aeromonas
hydrophila subsp. hydrophila (strain ATCC 7966 / NCIB
9240)
Length = 319
Score = 51.2 bits (117), Expect = 3e-05
Identities = 28/72 (38%), Positives = 41/72 (56%), Gaps = 2/72 (2%)
Frame = +1
Query: 529 SAGGSVAAAVKLNKQASEICINWGGGLHHAKKSEASGFCYVNDIVLGILELLKYH--QRV 702
S G ++AA+ +Q + I+ GG HHA + SGFC ND+V+ L ++V
Sbjct: 113 SVGATLAASRHALEQGCGLQIS--GGYHHAHRDVGSGFCLFNDLVIAAQVCLDEGRCEQV 170
Query: 703 LYIDIDVHHGDG 738
L +D+DVH GDG
Sbjct: 171 LIVDLDVHQGDG 182
>UniRef50_Q4CZ55 Cluster: Histone deacetylase, putative; n=2;
Trypanosoma cruzi|Rep: Histone deacetylase, putative -
Trypanosoma cruzi
Length = 661
Score = 51.2 bits (117), Expect = 3e-05
Identities = 45/173 (26%), Positives = 77/173 (44%), Gaps = 9/173 (5%)
Frame = +1
Query: 283 KPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVSEYNKQ 462
+P R++ T L GL + H A E+ HS +I + + + + +
Sbjct: 128 RPGRLKRTLEHLRAIGLLQCCRRISRHVARTKELRLVHSIAHIDSVDQLEVAALLRHPET 187
Query: 463 MQRFNVGEDCPVFDGLYEFCQLSAGGSVAAAVKL--NKQASEICINWGGGLHHAKKSEAS 636
++VG+D + +++ G +AAA+ + + + + G HHA +EAS
Sbjct: 188 S--YSVGQDLYANTSTSKAARMAVGCVIAAALSVVRGEVMNAFALVRPPG-HHAGVNEAS 244
Query: 637 GFCYVNDIVLGI----LELLKY---HQRVLYIDIDVHHGDGVEXAFYTTDRVM 774
GFC+ N++ + + EL + R L D DVHH DG E FY V+
Sbjct: 245 GFCFFNNVAVAVRVAQQELRQQGISAPRALVFDWDVHHCDGTESIFYEDPSVV 297
>UniRef50_O27262 Cluster: Uncharacterized protein MTH_1194; n=1;
Methanothermobacter thermautotrophicus str. Delta H|Rep:
Uncharacterized protein MTH_1194 - Methanobacterium
thermoautotrophicum
Length = 331
Score = 51.2 bits (117), Expect = 3e-05
Identities = 30/90 (33%), Positives = 43/90 (47%), Gaps = 2/90 (2%)
Frame = +1
Query: 511 YEFCQLSAGGSVAAAVKLNKQASEICINWGGGLHHAKKSEASGFCYVNDIVLGILELLKY 690
+ +LSAGG++ AA + + + G HHA + GFC N+I + I +
Sbjct: 85 FSVARLSAGGAMLAAEEALRDGWSYSLGRPPG-HHATYDRSMGFCIFNNIAIAIEHARRN 143
Query: 691 H--QRVLYIDIDVHHGDGVEXAFYTTDRVM 774
R L +D DVHHG+G FY VM
Sbjct: 144 LGVSRPLVLDFDVHHGNGTSSIFYRDRDVM 173
>UniRef50_UPI0000D561E8 Cluster: PREDICTED: similar to CG1770-PA,
isoform A; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to CG1770-PA, isoform A - Tribolium castaneum
Length = 883
Score = 50.8 bits (116), Expect = 4e-05
Identities = 21/57 (36%), Positives = 33/57 (57%), Gaps = 2/57 (3%)
Frame = +1
Query: 610 HHAKKSEASGFCYVNDIVLGILELLKYHQ--RVLYIDIDVHHGDGVEXAFYTTDRVM 774
HHA+ +A GFC+ N + + L + H+ ++L D VHHG+G + FY RV+
Sbjct: 606 HHAEPQQAMGFCFFNSVAIAARVLQREHRVHKILIFDWGVHHGNGTQDIFYDDPRVL 662
>UniRef50_A2AWS5 Cluster: Histone deacetylase 5; n=21;
Euarchontoglires|Rep: Histone deacetylase 5 - Mus
musculus (Mouse)
Length = 1030
Score = 50.8 bits (116), Expect = 4e-05
Identities = 22/57 (38%), Positives = 35/57 (61%), Gaps = 2/57 (3%)
Frame = +1
Query: 610 HHAKKSEASGFCYVNDIVLG--ILELLKYHQRVLYIDIDVHHGDGVEXAFYTTDRVM 774
HHA++S A GFC+ N + + +L+ +VL +D D+HHG+G + AFY V+
Sbjct: 740 HHAEESTAMGFCFFNSVAITAKLLQQKLSVGKVLIVDWDIHHGNGTQQAFYNDPSVL 796
>UniRef50_Q1AYS6 Cluster: Histone deacetylase superfamily; n=1;
Rubrobacter xylanophilus DSM 9941|Rep: Histone
deacetylase superfamily - Rubrobacter xylanophilus
(strain DSM 9941 / NBRC 16129)
Length = 342
Score = 50.8 bits (116), Expect = 4e-05
Identities = 30/97 (30%), Positives = 45/97 (46%), Gaps = 1/97 (1%)
Frame = +1
Query: 487 DCPVFDGLYEFCQLSAGGSVAAAVKLNKQASEICINWGGGLHHAKKSEASGFCYVNDIVL 666
D + G +E L+AG + AA A+ + G HHA + A GFC +N+ +
Sbjct: 81 DTALGPGSWEAALLAAGAAAGAAEAALSGAASFALVRPPG-HHAGRGRAMGFCLINNAAV 139
Query: 667 GILELLKYH-QRVLYIDIDVHHGDGVEXAFYTTDRVM 774
+RV +D DVHHG+G + FY V+
Sbjct: 140 AAAHARALGARRVAVLDWDVHHGNGTQEIFYAAGDVL 176
>UniRef50_A6VZD7 Cluster: Histone deacetylase superfamily; n=2;
Marinomonas|Rep: Histone deacetylase superfamily -
Marinomonas sp. MWYL1
Length = 308
Score = 50.8 bits (116), Expect = 4e-05
Identities = 46/170 (27%), Positives = 75/170 (44%), Gaps = 3/170 (1%)
Frame = +1
Query: 271 GHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYI-RFLRSIRPDNVS 447
GH + + L G+ Y P + + H +Y+ RF+R
Sbjct: 21 GHRFPMRKFGLLAESLREQGILTDENEYTPAPLSLKVLMAAHHKEYVQRFIRG------- 73
Query: 448 EYNKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAAVKLNKQASEICINWGGGLHHAKKS 627
E +K+ ++ +G P + L E + G++ +L + C + GG HHA S
Sbjct: 74 ELSKREEK-EIG--LPWSEWLVERTLRAVSGTMLTT-ELAFEHGLAC-HLAGGTHHAHPS 128
Query: 628 EASGFCYVNDIVLGILELL--KYHQRVLYIDIDVHHGDGVEXAFYTTDRV 771
SGFC ND+ + L ++ +++L +D DVH GDG AF+ DRV
Sbjct: 129 HGSGFCIFNDLAVAALAMIGSGRAKKILILDCDVHQGDGT-IAFF-KDRV 176
>UniRef50_A3ZYN7 Cluster: Acetoin utilization protein; n=3;
Planctomycetaceae|Rep: Acetoin utilization protein -
Blastopirellula marina DSM 3645
Length = 311
Score = 50.4 bits (115), Expect = 5e-05
Identities = 31/101 (30%), Positives = 48/101 (47%), Gaps = 4/101 (3%)
Frame = +1
Query: 478 VGEDCPVFDGLYEFCQLSAGGSVAAA--VKLNKQASEICINWGGGLHHAKKSEASGFCYV 651
+ ED V Y L+ G ++ A V ++ +C+ G HHA + GFC
Sbjct: 77 IEEDTVVSHDSYHVATLAVGAAMDATRRVLAGDSSNALCLVRPPG-HHATPTMPMGFCLF 135
Query: 652 NDIVLGILELLKYHQ--RVLYIDIDVHHGDGVEXAFYTTDR 768
N + + L RVL +D DVHHG+G + AF+ ++R
Sbjct: 136 NSVAIAAQYALSKLDLDRVLIVDWDVHHGNGTQDAFWESER 176
>UniRef50_A1I9M7 Cluster: Histone deacetylase superfamily; n=1;
Candidatus Desulfococcus oleovorans Hxd3|Rep: Histone
deacetylase superfamily - Candidatus Desulfococcus
oleovorans Hxd3
Length = 578
Score = 50.4 bits (115), Expect = 5e-05
Identities = 23/56 (41%), Positives = 29/56 (51%)
Frame = +1
Query: 610 HHAKKSEASGFCYVNDIVLGILELLKYHQRVLYIDIDVHHGDGVEXAFYTTDRVMT 777
HHA+ S GFCY N + L H RV +DID HHG+G + FY + T
Sbjct: 393 HHAETSMFGGFCYFNSAAIAA-HYLSRHGRVAILDIDYHHGNGQQEIFYRRADIFT 447
>UniRef50_Q5VP96 Cluster: HGWP repeat containing protein-like; n=1;
Oryza sativa (japonica cultivar-group)|Rep: HGWP repeat
containing protein-like - Oryza sativa subsp. japonica
(Rice)
Length = 145
Score = 50.4 bits (115), Expect = 5e-05
Identities = 25/72 (34%), Positives = 37/72 (51%)
Frame = +1
Query: 379 EMTKFHSDDYIRFLRSIRPDNVSEYNKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAAV 558
++ SDDY+ L ++ P+ + + RFNV EDCP+F G Y +CQ AG A +
Sbjct: 67 DLRLLRSDDYVASLPAVLPEL---WICSLCRFNVDEDCPIFHGFYIYCQTCAGDCARAII 123
Query: 559 KLNKQASEICIN 594
A + IN
Sbjct: 124 DRYHGAQNVVIN 135
>UniRef50_Q9U266 Cluster: Putative uncharacterized protein hda-6;
n=2; Caenorhabditis|Rep: Putative uncharacterized
protein hda-6 - Caenorhabditis elegans
Length = 517
Score = 50.4 bits (115), Expect = 5e-05
Identities = 34/129 (26%), Positives = 58/129 (44%), Gaps = 2/129 (1%)
Frame = +1
Query: 364 KATADEMTKFHSDDYIRFLRSIRPDNVSEYNKQMQRFNVGEDCPVFDGLYEFCQLSAGGS 543
+A E+ H+ Y+ ++S V + ++ ED V + +L+AG S
Sbjct: 58 EAEESEILAVHTKRYVDDVKSTETMTVEQQESFCTKY---EDIYVNSATWHRAKLAAGAS 114
Query: 544 V--AAAVKLNKQASEICINWGGGLHHAKKSEASGFCYVNDIVLGILELLKYHQRVLYIDI 717
+ +V K+ I G HHA E GFC N++ + ++ Q+VL +D
Sbjct: 115 IDLMTSVMAAKRPGIAFIRPPG--HHAMPDEGCGFCIFNNVAIAAKAAIQNGQKVLIVDY 172
Query: 718 DVHHGDGVE 744
DVH G+G +
Sbjct: 173 DVHAGNGTQ 181
>UniRef50_Q5KNI3 Cluster: Histone deacetylase, putative; n=2;
Filobasidiella neoformans|Rep: Histone deacetylase,
putative - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 541
Score = 50.4 bits (115), Expect = 5e-05
Identities = 21/47 (44%), Positives = 29/47 (61%), Gaps = 2/47 (4%)
Frame = +1
Query: 610 HHAKKSEASGFCYVNDIVLGILELLKYH--QRVLYIDIDVHHGDGVE 744
HH + SGFCYVN++V+G L H R + ID D+HHG+G +
Sbjct: 232 HHCGEDAPSGFCYVNNVVIGALHGYLQHDIDRAIIIDFDLHHGNGTQ 278
>UniRef50_O27994 Cluster: Acetylpolyamine aminohydrolase, putative;
n=2; Euryarchaeota|Rep: Acetylpolyamine aminohydrolase,
putative - Archaeoglobus fulgidus
Length = 187
Score = 50.4 bits (115), Expect = 5e-05
Identities = 28/90 (31%), Positives = 46/90 (51%), Gaps = 2/90 (2%)
Frame = +1
Query: 508 LYEFCQLSAGGSVAAAVKLNKQASEICINWGGGLHHAKKSEASGFCYVNDIVLGILELLK 687
+YE L+ GG++ A+ + + I G HHA + GFCY N+I + + +LL
Sbjct: 9 IYEVAVLAVGGAILASEIAFNEPAFGAIRPPG--HHASPDSSWGFCYFNNIAIAVKKLLV 66
Query: 688 YH--QRVLYIDIDVHHGDGVEXAFYTTDRV 771
++ + +D D+H GDG AF + V
Sbjct: 67 EGRIKKAVIVDFDLHFGDGTANAFAGVEEV 96
>UniRef50_UPI00005A01A4 Cluster: PREDICTED: similar to histone
deacetylase 3 isoform 3; n=1; Canis lupus
familiaris|Rep: PREDICTED: similar to histone
deacetylase 3 isoform 3 - Canis familiaris
Length = 75
Score = 50.0 bits (114), Expect = 6e-05
Identities = 18/25 (72%), Positives = 24/25 (96%)
Frame = +1
Query: 271 GHPMKPHRIRMTHNLLLNYGLYRKM 345
GHPMKPHR+ +TH+L+L+YGLY+KM
Sbjct: 21 GHPMKPHRLALTHSLVLHYGLYKKM 45
>UniRef50_UPI000065FABE Cluster: Histone deacetylase 6 (HD6).; n=1;
Takifugu rubripes|Rep: Histone deacetylase 6 (HD6). -
Takifugu rubripes
Length = 1154
Score = 50.0 bits (114), Expect = 6e-05
Identities = 38/171 (22%), Positives = 72/171 (42%), Gaps = 4/171 (2%)
Frame = +1
Query: 274 HPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVSEY 453
HP +P R+ L L ++ +P +AT +E+ HS Y+ ++S + E
Sbjct: 63 HPERPERVASIMEHLEQQDLLSRVTRVQPREAT-EELLLCHSQHYVDLMKSTQTMTEEEL 121
Query: 454 NKQMQRFNVGEDCPVFDGLYEFCQLSAGG--SVAAAVKLNKQASEICINWGGGLHHAKKS 627
+ ++ + + + ++ G + V ++ + + G HHA+K
Sbjct: 122 HSLSDKY---DSIYLHPESFSVAVMAVGSVLQLVDQVMTSELRNGFAVVRPPG-HHAQKD 177
Query: 628 EASGFCYVNDIVLGILELLKYHQ--RVLYIDIDVHHGDGVEXAFYTTDRVM 774
+GF N++ + H RVL +D DVHHG G++ F V+
Sbjct: 178 LPNGFSIFNNVAIAARYAQTRHSVSRVLIVDWDVHHGQGIQYLFQEDPSVL 228
Score = 49.6 bits (113), Expect = 9e-05
Identities = 46/176 (26%), Positives = 74/176 (42%), Gaps = 9/176 (5%)
Frame = +1
Query: 274 HPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFH---SDDYIRFLRSIRPDNV 444
HP +P RI + GL + AT +E+ H SD + +++P
Sbjct: 479 HPEQPQRISKIFSQHQELGLVDRCRSIPARLATEEELCMCHRSGSDIWHPLTATMKP--- 535
Query: 445 SEYNKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAAVKL--NKQASEICINWGGGLHHA 618
E +K FN + + ++ L+AGG + ++ + + + I G HHA
Sbjct: 536 RELHKLGDEFN---SIYINNQSFQAALLAAGGCFSGVEQILAGQVRNGVAIVRPPG-HHA 591
Query: 619 KKSEASGFCYVNDIVLGILELLKYHQ----RVLYIDIDVHHGDGVEXAFYTTDRVM 774
++ GFC+ N L K Q VL +D DVHHG+G + F D V+
Sbjct: 592 ERDFPCGFCFFNTAALAARHAQKLSQDAPLHVLILDWDVHHGNGTQHMFEDDDSVL 647
>UniRef50_Q1NWE2 Cluster: Histone deacetylase superfamily; n=2;
delta proteobacterium MLMS-1|Rep: Histone deacetylase
superfamily - delta proteobacterium MLMS-1
Length = 349
Score = 50.0 bits (114), Expect = 6e-05
Identities = 31/92 (33%), Positives = 50/92 (54%), Gaps = 4/92 (4%)
Frame = +1
Query: 511 YEFCQLSAGGSVAAA--VKLNKQASEICINWGGGLHHAKKSEASGFCYVNDIVLGILELL 684
YE L+AG +VAA V + + + G HHA+ + +SGFC N+I +
Sbjct: 91 YEAACLAAGAAVAAVELVAAGEVDNAFALVRPPG-HHAEHAHSSGFCLFNNIAIAAHYAR 149
Query: 685 KY--HQRVLYIDIDVHHGDGVEXAFYTTDRVM 774
+ +R+L D D+HHG+G + AF +D+V+
Sbjct: 150 QKLGFKRILIFDWDLHHGNGTQHAFDDSDQVL 181
>UniRef50_Q8I9J6 Cluster: Histone deacetylase dHDAC4 isoform b; n=7;
Sophophora|Rep: Histone deacetylase dHDAC4 isoform b -
Drosophila melanogaster (Fruit fly)
Length = 1255
Score = 50.0 bits (114), Expect = 6e-05
Identities = 23/59 (38%), Positives = 37/59 (62%), Gaps = 4/59 (6%)
Frame = +1
Query: 610 HHAKKSEASGFCYVNDIVLGILELLKYH----QRVLYIDIDVHHGDGVEXAFYTTDRVM 774
HHA+ + A GFC+ N I + +LL+ +R+L +D DVHHG+G + AFY + ++
Sbjct: 970 HHAEANLAMGFCFFNSIAIAA-KLLRQRMPEVRRILIVDWDVHHGNGTQQAFYQSPDIL 1027
>UniRef50_Q1DTF8 Cluster: Putative uncharacterized protein; n=1;
Coccidioides immitis|Rep: Putative uncharacterized
protein - Coccidioides immitis
Length = 724
Score = 50.0 bits (114), Expect = 6e-05
Identities = 50/188 (26%), Positives = 84/188 (44%), Gaps = 21/188 (11%)
Frame = +1
Query: 274 HPMKPHRIRMTHNLLLNYGLYRKMEIYRP-----------HKATADEMTKFHSDDYIRFL 420
HP P RI + L GL + RP AT +E++ H ++ F+
Sbjct: 140 HPEDPRRIYYIYKELCKAGLVDDPDASRPLVSQPLLRIPARDATHEEISLIHDSEHYDFV 199
Query: 421 RSIRPDNVSEYNKQMQRFNVGEDCPVFDGL-YEFCQLSAGGSVAA--AVKLNKQASEICI 591
S + ++SE ++ D F+ L + L+ GG++ AV K + I +
Sbjct: 200 LSTK--DMSE--DELIALESTRDSIYFNTLTFTSAILACGGAIETCKAVVSGKVKNAIAV 255
Query: 592 NWGGGLHHAKKSEASGFCYVNDIVLGILELLKYH----QRVLYIDIDVHH---GDGVEXA 750
G HHA++ +A GFC N++ + K ++++ +D DVHH G+GV+ A
Sbjct: 256 IRPPG-HHAEQCQAMGFCLFNNVSVAARVCQKTFKDKCRKIMIVDWDVHHDLLGNGVQNA 314
Query: 751 FYTTDRVM 774
FY V+
Sbjct: 315 FYDDPNVL 322
>UniRef50_A3VQ74 Cluster: Probable histone deacetylase/AcuC/AphA
family protein; n=1; Parvularcula bermudensis
HTCC2503|Rep: Probable histone deacetylase/AcuC/AphA
family protein - Parvularcula bermudensis HTCC2503
Length = 299
Score = 49.2 bits (112), Expect = 1e-04
Identities = 27/74 (36%), Positives = 38/74 (51%), Gaps = 2/74 (2%)
Frame = +1
Query: 523 QLSAGGSVAAAVKLNKQASEICINWGGGLHHAKKSEASGFCYVNDIVLGILELLK--YHQ 696
Q + GG++AAA + K+ + GG HHA SG+C ND + LL
Sbjct: 91 QRTVGGALAAARRALKEG--LSGQLAGGTHHAHAEAGSGYCIYNDFAVVARTLLNEGVVD 148
Query: 697 RVLYIDIDVHHGDG 738
R+ +D+DVH GDG
Sbjct: 149 RIAIVDLDVHQGDG 162
>UniRef50_Q2FQ17 Cluster: Histone deacetylase superfamily; n=1;
Methanospirillum hungatei JF-1|Rep: Histone deacetylase
superfamily - Methanospirillum hungatei (strain JF-1 /
DSM 864)
Length = 322
Score = 49.2 bits (112), Expect = 1e-04
Identities = 29/92 (31%), Positives = 45/92 (48%), Gaps = 4/92 (4%)
Frame = +1
Query: 511 YEFCQLSAGGSVAAAVKLNKQASE--ICINWGGGLHHAKKSEASGFCYVNDIVLGILELL 684
YE SA G + A L + ++ +N G HH GFCY+N+ + + L
Sbjct: 75 YEHALKSAFGCLTAGEMLIQDEAQNAFVLNRPPG-HHTYADRGGGFCYLNNAAI-LARYL 132
Query: 685 KYH--QRVLYIDIDVHHGDGVEXAFYTTDRVM 774
+ H ++++ ID D HHG+G E FY V+
Sbjct: 133 QMHGMEKIMIIDWDAHHGNGTESIFYDDPSVL 164
>UniRef50_P56523 Cluster: Histone deacetylase clr3; n=1;
Schizosaccharomyces pombe|Rep: Histone deacetylase clr3
- Schizosaccharomyces pombe (Fission yeast)
Length = 687
Score = 49.2 bits (112), Expect = 1e-04
Identities = 36/144 (25%), Positives = 69/144 (47%), Gaps = 7/144 (4%)
Frame = +1
Query: 364 KATADEMTKFHSDDYIRFLRSIRPDNVSEYNKQMQRFNVGEDCPVFDGLYEFC-QLSAGG 540
+AT +E+ + HS + + R + +S ++ + D ++ FC +L+ G
Sbjct: 114 EATLEELLQVHSQEM--YDRVTNTEKMS--HEDLANLEKISDSLYYNNESAFCARLACGS 169
Query: 541 SV--AAAVKLNKQASEICINWGGGLHHAKKSEASGFCYVNDIVLGILELLKYH----QRV 702
++ AV + + + G HHA+ + GFC N++ + +L+ +RV
Sbjct: 170 AIETCTAVVTGQVKNAFAVVRPPG-HHAEPHKPGGFCLFNNVSVTARSMLQRFPDKIKRV 228
Query: 703 LYIDIDVHHGDGVEXAFYTTDRVM 774
L +D D+HHG+G + AFY V+
Sbjct: 229 LIVDWDIHHGNGTQMAFYDDPNVL 252
>UniRef50_Q3IF01 Cluster: Putative histone deacetylase family
protein; n=3; Alteromonadales|Rep: Putative histone
deacetylase family protein - Pseudoalteromonas
haloplanktis (strain TAC 125)
Length = 306
Score = 48.8 bits (111), Expect = 1e-04
Identities = 43/172 (25%), Positives = 76/172 (44%), Gaps = 5/172 (2%)
Frame = +1
Query: 274 HPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRP-DNVSE 450
HP P R+ ++ LL GL +E + KA + H + + F+ S P + +
Sbjct: 20 HPECPERLDAINDRLLASGLDIAIEQKQAPKAQREHYLLAHDESLVSFVESKIPTQGLVD 79
Query: 451 YNKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAAVKL---NKQASEICINWGGGLHHAK 621
+ CP D L + + + G + A ++ N A+ + G HHA
Sbjct: 80 LDGDTWL------CP--DSL-KAIERAVGAGILAVDEILEGNLDAAFCSVRPPG--HHAN 128
Query: 622 KSEASGFCYVNDIVLGI-LELLKYHQRVLYIDIDVHHGDGVEXAFYTTDRVM 774
++ +SGFC N++ + + K +R+ +D DVHHG+G + F V+
Sbjct: 129 RTTSSGFCVFNNLAIAVKYAQSKGVKRIAIVDFDVHHGNGTQDIFIDDKNVL 180
>UniRef50_Q1VK67 Cluster: Histone deacetylase family protein; n=1;
Psychroflexus torquis ATCC 700755|Rep: Histone
deacetylase family protein - Psychroflexus torquis ATCC
700755
Length = 344
Score = 48.8 bits (111), Expect = 1e-04
Identities = 24/64 (37%), Positives = 32/64 (50%), Gaps = 2/64 (3%)
Frame = +1
Query: 592 NWGGGLHHAKKSEASGFCYVNDIVLGILELLKY--HQRVLYIDIDVHHGDGVEXAFYTTD 765
N GG HHA + SG+C ND+ + L + RV +D+DVH GDG
Sbjct: 138 NMAGGTHHAHREFGSGYCVFNDLAVCALHAITSLGVGRVAVLDLDVHQGDGTASILAGEQ 197
Query: 766 RVMT 777
RV+T
Sbjct: 198 RVLT 201
>UniRef50_A6LM84 Cluster: Histone deacetylase superfamily; n=1;
Thermosipho melanesiensis BI429|Rep: Histone deacetylase
superfamily - Thermosipho melanesiensis BI429
Length = 315
Score = 48.8 bits (111), Expect = 1e-04
Identities = 21/51 (41%), Positives = 32/51 (62%), Gaps = 2/51 (3%)
Frame = +1
Query: 610 HHAKKSEASGFCYVNDIVLGILELLK--YHQRVLYIDIDVHHGDGVEXAFY 756
HHA K A G+C+ N+ + I + L+ Y +R+ +DID HHG+G + FY
Sbjct: 131 HHASKDFAGGYCFFNNAAI-IAKYLQSIYQKRICILDIDFHHGNGTQEIFY 180
>UniRef50_Q70I53 Cluster: Histone deacetylase-like amidohydrolase;
n=2; Proteobacteria|Rep: Histone deacetylase-like
amidohydrolase - Alcaligenes sp. (strain DSM 11172)
(Bordetella sp. (strain FB188))
Length = 369
Score = 48.8 bits (111), Expect = 1e-04
Identities = 31/97 (31%), Positives = 48/97 (49%), Gaps = 5/97 (5%)
Frame = +1
Query: 502 DGLYEFCQLSAGGSVAAAVKL---NKQASEICINWGGGLHHAKKSEASGFCYVND--IVL 666
+G E +LSAGG+V ++ A +N G HHA + A GFC N+ +
Sbjct: 105 NGGLEIARLSAGGAVELTRRVATGELSAGYALVNPPG--HHAPHNAAMGFCIFNNTSVAA 162
Query: 667 GILELLKYHQRVLYIDIDVHHGDGVEXAFYTTDRVMT 777
G + +RV +D DVHHG+G + ++ V+T
Sbjct: 163 GYARAVLGMERVAILDWDVHHGNGTQDIWWNDPSVLT 199
>UniRef50_Q96DB2 Cluster: Histone deacetylase 11; n=22;
Eumetazoa|Rep: Histone deacetylase 11 - Homo sapiens
(Human)
Length = 347
Score = 48.8 bits (111), Expect = 1e-04
Identities = 26/64 (40%), Positives = 30/64 (46%), Gaps = 3/64 (4%)
Frame = +1
Query: 589 INWGGGLHHAKKSEASGFCYVNDIVLGI---LELLKYHQRVLYIDIDVHHGDGVEXAFYT 759
IN GGG HH GFC DI L I E ++ R ID+D H G+G E F
Sbjct: 135 INVGGGFHHCSSDRGGGFCAYADITLAIKFLFERVEGISRATIIDLDAHQGNGHERDFMD 194
Query: 760 TDRV 771
RV
Sbjct: 195 DKRV 198
>UniRef50_Q9HSP7 Cluster: Acetoin utilization protein; n=5;
Halobacteriaceae|Rep: Acetoin utilization protein -
Halobacterium salinarium (Halobacterium halobium)
Length = 338
Score = 48.4 bits (110), Expect = 2e-04
Identities = 22/51 (43%), Positives = 28/51 (54%), Gaps = 2/51 (3%)
Frame = +1
Query: 610 HHAKKSEASGFCYVNDIVLGILELLKYH--QRVLYIDIDVHHGDGVEXAFY 756
HHA +A GFC+VN+ + L H RV D DVHHG+G + FY
Sbjct: 121 HHAITDDAMGFCFVNNAAVAAQHALDAHGLDRVAIFDWDVHHGNGTQDIFY 171
>UniRef50_Q9RW36 Cluster: Histone deacetylase/AcuC/AphA family
protein; n=4; Deinococci|Rep: Histone
deacetylase/AcuC/AphA family protein - Deinococcus
radiodurans
Length = 301
Score = 48.0 bits (109), Expect = 3e-04
Identities = 30/72 (41%), Positives = 42/72 (58%), Gaps = 2/72 (2%)
Frame = +1
Query: 529 SAGGSVAAAVKLNKQASEICINWGGGLHHAKKSEASGFCYVND-IVLGILELLK-YHQRV 702
+AGGS+AA + Q++ N GG HHA A GFC VND +L + L + +RV
Sbjct: 92 AAGGSLAALH--DAQSTGWGANLAGGTHHAFHDRAEGFCLVNDAAILTRIALDRGLARRV 149
Query: 703 LYIDIDVHHGDG 738
+D+DVH G+G
Sbjct: 150 ATLDLDVHQGNG 161
>UniRef50_A5VD94 Cluster: Histone deacetylase superfamily; n=6;
Alphaproteobacteria|Rep: Histone deacetylase superfamily
- Sphingomonas wittichii RW1
Length = 315
Score = 48.0 bits (109), Expect = 3e-04
Identities = 28/84 (33%), Positives = 43/84 (51%), Gaps = 2/84 (2%)
Frame = +1
Query: 493 PVFDGLYEFCQLSAGGSVAAAVKLNKQASEICINWGGGLHHAKKSEASGFCYVNDIVLGI 672
PV + + L+ GG+ AA KL + N GG HHA +G+C ND+ +
Sbjct: 80 PVTERVARRAFLAPGGTWLAA-KLALRHG-YAANGAGGSHHAMADSGAGYCVFNDLAIAA 137
Query: 673 LELL--KYHQRVLYIDIDVHHGDG 738
L+ + R++ +D+DVH GDG
Sbjct: 138 NRLIVERDAARIMIVDLDVHQGDG 161
>UniRef50_UPI0000F2108C Cluster: PREDICTED: hypothetical protein;
n=1; Danio rerio|Rep: PREDICTED: hypothetical protein -
Danio rerio
Length = 673
Score = 47.6 bits (108), Expect = 3e-04
Identities = 20/57 (35%), Positives = 31/57 (54%), Gaps = 2/57 (3%)
Frame = +1
Query: 610 HHAKKSEASGFCYVNDIVLGILELLKY--HQRVLYIDIDVHHGDGVEXAFYTTDRVM 774
HHA S GFC+ N + + +L + ++L +D DVHHG+G + FY V+
Sbjct: 391 HHADPSNPMGFCFFNSVAIAAKQLQQKLSASKILIVDWDVHHGNGTQEIFYNDPSVL 447
>UniRef50_Q30PJ4 Cluster: Histone deacetylase superfamily; n=1;
Thiomicrospira denitrificans ATCC 33889|Rep: Histone
deacetylase superfamily - Thiomicrospira denitrificans
(strain ATCC 33889 / DSM 1351)
Length = 577
Score = 47.6 bits (108), Expect = 3e-04
Identities = 20/56 (35%), Positives = 30/56 (53%)
Frame = +1
Query: 610 HHAKKSEASGFCYVNDIVLGILELLKYHQRVLYIDIDVHHGDGVEXAFYTTDRVMT 777
HHA++ GFCY N + L + +V +D+D HHG+G + FY V+T
Sbjct: 392 HHAERRTLGGFCYFNSAAVAAHHLSSFG-KVAVLDVDFHHGNGTQDIFYERRDVLT 446
>UniRef50_Q128P1 Cluster: Histone deacetylase superfamily; n=16;
Bacteria|Rep: Histone deacetylase superfamily -
Polaromonas sp. (strain JS666 / ATCC BAA-500)
Length = 337
Score = 47.6 bits (108), Expect = 3e-04
Identities = 36/108 (33%), Positives = 48/108 (44%), Gaps = 13/108 (12%)
Frame = +1
Query: 493 PVFDGLYEFCQLSAGGSVAAA---VKLNKQASEICINWGGGLHHAKKSEASGFCYVND-I 660
P G+ E + SAG +VAAA + + + N GG HHA + SGFC ND
Sbjct: 102 PWSPGMAERARRSAGATVAAARVALGTGTRPQGVAANMAGGTHHAYAHKGSGFCVFNDSA 161
Query: 661 VLGILELLKYHQR---------VLYIDIDVHHGDGVEXAFYTTDRVMT 777
V L ++ +R V ID+DVH G+G F V T
Sbjct: 162 VTARLMQAEWGRRHRPDRKPLQVAVIDLDVHQGNGTAHIFANDPSVFT 209
>UniRef50_A4AX75 Cluster: Histone deacetylase/AcuC/AphA family
protein; n=4; Alteromonadales|Rep: Histone
deacetylase/AcuC/AphA family protein - Alteromonas
macleodii 'Deep ecotype'
Length = 326
Score = 47.6 bits (108), Expect = 3e-04
Identities = 23/57 (40%), Positives = 31/57 (54%), Gaps = 2/57 (3%)
Frame = +1
Query: 610 HHAKKSEASGFCYVNDIVLGILELLKYH--QRVLYIDIDVHHGDGVEXAFYTTDRVM 774
HHA A GFC N+IV+ L+ + +RV +D DVHHG+G E R+M
Sbjct: 140 HHATYDSAMGFCVFNNIVIAARYALQNYGLKRVAIVDFDVHHGNGTEQIVAGDQRIM 196
>UniRef50_A0LFA3 Cluster: Histone deacetylase superfamily; n=3;
Deltaproteobacteria|Rep: Histone deacetylase superfamily
- Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB)
Length = 248
Score = 47.6 bits (108), Expect = 3e-04
Identities = 28/80 (35%), Positives = 42/80 (52%), Gaps = 2/80 (2%)
Frame = +1
Query: 505 GLYEFCQLSAGGSVAAAVKLNKQASEICINWGGGLHHAKKSEASGFCYVNDIVLGILELL 684
GLY L+AGG++ A+ K+ I G HHA GFCY N++ + + L
Sbjct: 64 GLYNIACLAAGGAIQTALTGLKEPCFGLIRPPG--HHASADSYWGFCYFNNMAVALDHLK 121
Query: 685 KY-HQRVLYI-DIDVHHGDG 738
+ H + Y+ D D+H+GDG
Sbjct: 122 RNGHIKTAYVLDFDMHYGDG 141
>UniRef50_A0C8R8 Cluster: Chromosome undetermined scaffold_159,
whole genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_159,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 366
Score = 47.6 bits (108), Expect = 3e-04
Identities = 29/84 (34%), Positives = 42/84 (50%), Gaps = 2/84 (2%)
Frame = +1
Query: 526 LSAGGSVAAAVKLNKQASEICINWGGGLHHAKKSEASGFCYVNDI--VLGILELLKYHQR 699
L+ GS+ AA KL + IN GG HHA + GFC DI V+ L+ ++
Sbjct: 163 LATSGSIQAA-KLALEKGW-AINLSGGYHHASLNRGGGFCIYPDITLVVNYLKRCCNLKK 220
Query: 700 VLYIDIDVHHGDGVEXAFYTTDRV 771
++ +D+D H G+G E F V
Sbjct: 221 IVIVDLDAHQGNGYERDFLNDSSV 244
>UniRef50_Q8U2L6 Cluster: Aminohydrolase; n=4; Thermococcaceae|Rep:
Aminohydrolase - Pyrococcus furiosus
Length = 335
Score = 47.6 bits (108), Expect = 3e-04
Identities = 42/174 (24%), Positives = 74/174 (42%), Gaps = 7/174 (4%)
Frame = +1
Query: 274 HPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVSEY 453
HP P R+ + + + GL ++E P + T E K H DYI F++ ++
Sbjct: 20 HPENPKRLEIVLSKVRELGLEERIEEPNPVEETFVE--KIHDRDYINFVKEAVEKGITRL 77
Query: 454 NKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAAVK-LNKQASEICINWGGGLHHAKKSE 630
+ D V G + L+ G + +AA+ L+ + + G H ++
Sbjct: 78 DP---------DTYVSPGTWSAALLALGAARSAALSALHYGGLHMALVRPPGHHAGRRGR 128
Query: 631 ASG-----FCYVNDIVLGILELLKYHQ-RVLYIDIDVHHGDGVEXAFYTTDRVM 774
A G FC N+ ++ L + +V+ ID D HHG+G + F+ V+
Sbjct: 129 AMGAPTLGFCIFNNAASAVVTLKEEGVGKVVVIDFDAHHGNGTQEIFWNDPDVI 182
>UniRef50_Q987Q0 Cluster: Acetylpolyamine aminohydrolase; n=1;
Mesorhizobium loti|Rep: Acetylpolyamine aminohydrolase -
Rhizobium loti (Mesorhizobium loti)
Length = 346
Score = 47.2 bits (107), Expect = 5e-04
Identities = 30/116 (25%), Positives = 56/116 (48%), Gaps = 4/116 (3%)
Frame = +1
Query: 421 RSIRPDNVSEYNKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAA---VKLNKQASEICI 591
+ + PD++ + Q+ ++++ +G +E + S ++ AA ++ + +C
Sbjct: 99 KDVAPDSI---DAQLGQYSIDASTGFVEGTWEAVKASHDSALTAADLIIEGEQACFALCR 155
Query: 592 NWGGGLHHAKKSEASGFCYVNDIVLGILELLKYH-QRVLYIDIDVHHGDGVEXAFY 756
G HHA G+C+VN+ + LL RV +DID HHG+G + FY
Sbjct: 156 PPG---HHAGTDFNGGYCFVNNAAVAAQRLLDGGASRVTILDIDYHHGNGTQEIFY 208
>UniRef50_Q985Y7 Cluster: Mlr7469 protein; n=13;
Alphaproteobacteria|Rep: Mlr7469 protein - Rhizobium
loti (Mesorhizobium loti)
Length = 308
Score = 47.2 bits (107), Expect = 5e-04
Identities = 21/57 (36%), Positives = 31/57 (54%), Gaps = 2/57 (3%)
Frame = +1
Query: 610 HHAKKSEASGFCYVNDIVLGILELLKYH--QRVLYIDIDVHHGDGVEXAFYTTDRVM 774
HHA+K+ A GFC+ N + H +RV +D DVHHG+G + F+ V+
Sbjct: 124 HHAEKTTAMGFCFFNTAAIAARYAQNKHGAERVAVVDWDVHHGNGTQDIFWDDPSVL 180
>UniRef50_A5WHG1 Cluster: Histone deacetylase superfamily; n=17;
Bacteria|Rep: Histone deacetylase superfamily -
Psychrobacter sp. PRwf-1
Length = 302
Score = 47.2 bits (107), Expect = 5e-04
Identities = 21/54 (38%), Positives = 30/54 (55%), Gaps = 2/54 (3%)
Frame = +1
Query: 583 ICINWGGGLHHAKKSEASGFCYVNDIVLGILELLKYHQ--RVLYIDIDVHHGDG 738
+ +N GG HHA GFC ND+ + LL Q ++L +D+DVH G+G
Sbjct: 110 VSLNVAGGTHHAFADHGEGFCVFNDVCIASNLLLSRGQASKILIVDLDVHQGNG 163
>UniRef50_A5UTM3 Cluster: Histone deacetylase superfamily; n=4;
Bacteria|Rep: Histone deacetylase superfamily -
Roseiflexus sp. RS-1
Length = 298
Score = 47.2 bits (107), Expect = 5e-04
Identities = 37/134 (27%), Positives = 63/134 (47%), Gaps = 2/134 (1%)
Frame = +1
Query: 346 EIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVSEYNKQMQRFNVGEDCPVFDGLYEFCQ 525
E+ P A ++ + H+ DY L I+ +S+ ++M++ P L E +
Sbjct: 38 ELIVPAAADDRDILRAHTADY---LHRIQIGAMSD--REMRQIGF----PWSPHLVERSR 88
Query: 526 LSAGGSVAAAVKLNKQASEICINWGGGLHHAKKSEASGFCYVNDIVLG--ILELLKYHQR 699
S G ++AA + I + GG HHA G+C ND V+ +++ +R
Sbjct: 89 RSVGATIAAC-RTALSGDGIAASLAGGTHHAFADHGEGYCVFNDSVIAARVMQAEGRVRR 147
Query: 700 VLYIDIDVHHGDGV 741
V+ ID DVH G+G+
Sbjct: 148 VVIIDCDVHQGNGI 161
>UniRef50_Q7S8C9 Cluster: Putative uncharacterized protein
NCU07018.1; n=1; Neurospora crassa|Rep: Putative
uncharacterized protein NCU07018.1 - Neurospora crassa
Length = 1212
Score = 47.2 bits (107), Expect = 5e-04
Identities = 20/45 (44%), Positives = 27/45 (60%), Gaps = 2/45 (4%)
Frame = +1
Query: 610 HHAKKSEASGFCYVNDIVLGILELLKYH--QRVLYIDIDVHHGDG 738
HH S SGFC+VN++ +GI+ + H ID D+HHGDG
Sbjct: 419 HHCSASYPSGFCWVNNVHVGIMHAILSHGLTHAAIIDFDLHHGDG 463
>UniRef50_O28982 Cluster: Acetoin utilization protein, putative;
n=1; Archaeoglobus fulgidus|Rep: Acetoin utilization
protein, putative - Archaeoglobus fulgidus
Length = 189
Score = 47.2 bits (107), Expect = 5e-04
Identities = 25/58 (43%), Positives = 30/58 (51%), Gaps = 2/58 (3%)
Frame = +1
Query: 598 GGGLHHAKKSEASGFCYVNDIVLGILELL-KYHQ-RVLYIDIDVHHGDGVEXAFYTTD 765
G G HHA + G+C ND+VL I L K+ + RV ID D HHGDG D
Sbjct: 15 GAGGHHAGRDYFWGYCCFNDVVLAIQNLYDKFGELRVAIIDTDAHHGDGTRELIELND 72
>UniRef50_UPI000023CBFE Cluster: hypothetical protein FG05636.1;
n=1; Gibberella zeae PH-1|Rep: hypothetical protein
FG05636.1 - Gibberella zeae PH-1
Length = 1144
Score = 46.8 bits (106), Expect = 6e-04
Identities = 20/45 (44%), Positives = 26/45 (57%), Gaps = 2/45 (4%)
Frame = +1
Query: 610 HHAKKSEASGFCYVNDIVLGILELLKYH--QRVLYIDIDVHHGDG 738
HH S SGFC+VN++ +GI+ H ID D+HHGDG
Sbjct: 341 HHCSASHPSGFCWVNNVHVGIMHAALEHGLTHAAIIDFDLHHGDG 385
>UniRef50_A6EYD2 Cluster: Histone deacetylase superfamily protein;
n=1; Marinobacter algicola DG893|Rep: Histone
deacetylase superfamily protein - Marinobacter algicola
DG893
Length = 368
Score = 46.8 bits (106), Expect = 6e-04
Identities = 44/171 (25%), Positives = 76/171 (44%), Gaps = 4/171 (2%)
Frame = +1
Query: 274 HPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVSEY 453
+P P RI +LL + + I AT D++ + H+ ++ + S+R ++
Sbjct: 48 YPEHPGRITAIMDLLAREPI-PGVRIEPGKAATPDQLRRVHTTSFLDDIFSLRDESAW-- 104
Query: 454 NKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAA--AVKLNKQASEICINWGGGLHHAKKS 627
+V + V G E +++AG ++AA AV + S + G HHA+
Sbjct: 105 ------LDV-DTTAVSPGSVEAAEVAAGTAIAAVEAVVEGRTNSAFAMVRPPG-HHAEPV 156
Query: 628 EASGFCYVNDIVLGILELLKYH--QRVLYIDIDVHHGDGVEXAFYTTDRVM 774
A GFC N++ + +RVL +D D HHG+G + F+ M
Sbjct: 157 RARGFCLFNNVAVAAAHAQAELGCERVLIVDWDAHHGNGTQDIFWADPDTM 207
>UniRef50_Q2H2N4 Cluster: Putative uncharacterized protein; n=1;
Chaetomium globosum|Rep: Putative uncharacterized
protein - Chaetomium globosum (Soil fungus)
Length = 1145
Score = 46.4 bits (105), Expect = 8e-04
Identities = 20/45 (44%), Positives = 27/45 (60%), Gaps = 2/45 (4%)
Frame = +1
Query: 610 HHAKKSEASGFCYVNDIVLGILELLKYH--QRVLYIDIDVHHGDG 738
HH S SGFC+VN++ +GI+ + H ID D+HHGDG
Sbjct: 350 HHCSASHPSGFCWVNNVHVGIMHGVLSHGLTHAAIIDFDLHHGDG 394
>UniRef50_Q2IF50 Cluster: Histone deacetylase superfamily; n=1;
Anaeromyxobacter dehalogenans 2CP-C|Rep: Histone
deacetylase superfamily - Anaeromyxobacter dehalogenans
(strain 2CP-C)
Length = 324
Score = 46.0 bits (104), Expect = 0.001
Identities = 28/100 (28%), Positives = 50/100 (50%), Gaps = 5/100 (5%)
Frame = +1
Query: 487 DCPVFDGLYEFCQLSAGGSVAAAVKLNK---QASEICINWGGGLHHAKKSEASGFCYVND 657
+ PV G + +AG ++ AA ++ + +A+ + G HHA A G+C +N+
Sbjct: 91 ETPVSAGSWRAAVAAAGAAIEAAERVARGEARAAFALVRPPG--HHAWADRAGGYCLLNN 148
Query: 658 IVLGI--LELLKYHQRVLYIDIDVHHGDGVEXAFYTTDRV 771
+ + ++ +RVL +D DVHH DG + F+ V
Sbjct: 149 VAIAARAVQAAGLARRVLVVDWDVHHCDGTQSIFWEDSAV 188
>UniRef50_UPI0000F1E289 Cluster: PREDICTED: hypothetical protein;
n=1; Danio rerio|Rep: PREDICTED: hypothetical protein -
Danio rerio
Length = 650
Score = 45.6 bits (103), Expect = 0.001
Identities = 37/163 (22%), Positives = 68/163 (41%), Gaps = 2/163 (1%)
Frame = +1
Query: 292 RIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVSEYNKQMQR 471
R+ + L GL + ++ + AT +E+ HS++ + F P Y QM
Sbjct: 283 RVTSIWSRLQECGLRSQCKLLKGRSATVEELLSVHSEELVCFFTGPEP-----YRSQMDI 337
Query: 472 FNVGEDCPVFDGLYEFCQLSAGGSVAAAVKLNKQASEICINWGGGLHHAKKSEASGFCYV 651
+ ++ + L + + +A V + + G HHA +S+
Sbjct: 338 GTMWKNPRNSEALK--MAVGSVTELALCVARGDLRNGFAVVTPPG-HHASRSQTLDSIVF 394
Query: 652 NDIVLGILELLKYHQ--RVLYIDIDVHHGDGVEXAFYTTDRVM 774
N + + +L + + ++L +D DVHHG G E FYT V+
Sbjct: 395 NSVAIAAKQLQEQLKVKKILIVDWDVHHGSGTESIFYTDPSVL 437
>UniRef50_A4QWC2 Cluster: Putative uncharacterized protein; n=1;
Magnaporthe grisea|Rep: Putative uncharacterized protein
- Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 1124
Score = 45.6 bits (103), Expect = 0.001
Identities = 20/45 (44%), Positives = 27/45 (60%), Gaps = 2/45 (4%)
Frame = +1
Query: 610 HHAKKSEASGFCYVNDIVLGILELLKYH--QRVLYIDIDVHHGDG 738
HH S SGFC+VN++ +GI+ + H ID D+HHGDG
Sbjct: 341 HHCSASFPSGFCWVNNVHVGIMHGILSHGLTHAAIIDFDLHHGDG 385
>UniRef50_Q9YG09 Cluster: Putative uncharacterized protein; n=1;
Aeropyrum pernix|Rep: Putative uncharacterized protein -
Aeropyrum pernix
Length = 366
Score = 45.6 bits (103), Expect = 0.001
Identities = 40/166 (24%), Positives = 62/166 (37%), Gaps = 5/166 (3%)
Frame = +1
Query: 274 HPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVSEY 453
HP P R+ L G+Y+ +E P T+ HS Y+R + S +
Sbjct: 21 HPENPSRLVEAVRGLEESGVYKHLEAVTPPVGDVGLYTRVHSPAYLRHVLSTAESGLDWL 80
Query: 454 NKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAAVKLNKQASEICINWGGGLHHAKKSEA 633
+ D V G + G SV + + + G H + A
Sbjct: 81 DP---------DTYVGPGTLVALKRLGGASVEVYNIVRSGGEALLLGRPPGHHAGIRGRA 131
Query: 634 -----SGFCYVNDIVLGILELLKYHQRVLYIDIDVHHGDGVEXAFY 756
+GFC VN L I +L + + +D D+HHG+G + FY
Sbjct: 132 LGAPTAGFCIVNTAAL-IARMLSEQGKTVILDFDLHHGNGTQEIFY 176
>UniRef50_Q6AJC0 Cluster: Putative uncharacterized protein; n=1;
Desulfotalea psychrophila|Rep: Putative uncharacterized
protein - Desulfotalea psychrophila
Length = 324
Score = 45.2 bits (102), Expect = 0.002
Identities = 28/82 (34%), Positives = 44/82 (53%), Gaps = 4/82 (4%)
Frame = +1
Query: 511 YEFCQLSAGGSVAAAVKLNK-QASEI-CINWGGGLHHAKKSEASGFCYVNDIVLGILELL 684
Y+ L+AG + L A +I C+ G HHA+K + GFC+ N++++
Sbjct: 96 YQVAALAAGAGLKGIDLLEAGDARQIFCVIRPPG-HHAEKGKPFGFCFYNNVLIAARYWQ 154
Query: 685 -KY-HQRVLYIDIDVHHGDGVE 744
KY +RV ID D HHG+G++
Sbjct: 155 EKYGRRRVAVIDFDAHHGNGIQ 176
>UniRef50_Q4W9N7 Cluster: Histone deacetylase HosB; n=3;
Trichocomaceae|Rep: Histone deacetylase HosB -
Aspergillus fumigatus (Sartorya fumigata)
Length = 1191
Score = 45.2 bits (102), Expect = 0.002
Identities = 21/54 (38%), Positives = 29/54 (53%), Gaps = 2/54 (3%)
Frame = +1
Query: 583 ICINWGGGLHHAKKSEASGFCYVNDIVLGILELLKYH--QRVLYIDIDVHHGDG 738
+CI G HH S SGFC++N++ +GI H +D D+HHGDG
Sbjct: 354 VCIRPPG--HHCSTSHPSGFCWINNVHVGITYAAMTHGLTHAAILDFDLHHGDG 405
>UniRef50_Q57955 Cluster: Uncharacterized protein MJ0535; n=1;
Methanocaldococcus jannaschii|Rep: Uncharacterized
protein MJ0535 - Methanococcus jannaschii
Length = 343
Score = 45.2 bits (102), Expect = 0.002
Identities = 21/49 (42%), Positives = 32/49 (65%), Gaps = 1/49 (2%)
Frame = +1
Query: 631 ASGFCYVNDIVLGILELLK-YHQRVLYIDIDVHHGDGVEXAFYTTDRVM 774
++GFC N+I G L K Y ++V+ ID DVHHG+G + F+ +RV+
Sbjct: 136 SNGFCIFNNIA-GAARLAKNYMKKVIIIDFDVHHGNGTQEIFWNDNRVI 183
>UniRef50_Q0AUZ2 Cluster: Deacetylase family protrein; n=2;
Clostridiales|Rep: Deacetylase family protrein -
Syntrophomonas wolfei subsp. wolfei (strain Goettingen)
Length = 252
Score = 44.8 bits (101), Expect = 0.002
Identities = 28/81 (34%), Positives = 41/81 (50%), Gaps = 4/81 (4%)
Frame = +1
Query: 508 LYEFCQLSAGGSVAAAVKL--NKQASEICINWGGGLHHAKKSEASGFCYVNDIVLGILEL 681
+YE LSAG ++ AA + + A +C G HHA GFCY N+I + + +
Sbjct: 66 VYEMALLSAGAAIKAAERAAAGEPAFALCRPPG---HHASPDGFWGFCYFNNIAIALEKQ 122
Query: 682 LKYH--QRVLYIDIDVHHGDG 738
L+ L +D D+H GDG
Sbjct: 123 LQKGTINSALVVDFDLHFGDG 143
>UniRef50_Q2QWU2 Cluster: Histone deacetylase family protein,
expressed; n=4; Magnoliophyta|Rep: Histone deacetylase
family protein, expressed - Oryza sativa subsp. japonica
(Rice)
Length = 443
Score = 44.8 bits (101), Expect = 0.002
Identities = 47/149 (31%), Positives = 63/149 (42%), Gaps = 11/149 (7%)
Frame = +1
Query: 343 MEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVSEYNKQMQRFNVGEDCPVF--DGLYE 516
+EI A+ D++ HS YI L +S + + F G P + ++
Sbjct: 129 LEIQDFQPASLDDIALVHSRSYITGLEKA----MSRASDEGLIFIEGTG-PTYATQTTFQ 183
Query: 517 FCQLSAGG------SVAAAVKLN-KQASEICINWGGGLHHAKKSEASGFCYVNDIVLGIL 675
C LSAG SV AA KL K + G HHA GFC +I +
Sbjct: 184 ECLLSAGAGITLVDSVVAASKLGPKPPLGFALVRPPG-HHAVPEGPMGFCVFGNIAVAAR 242
Query: 676 ELLKYH--QRVLYIDIDVHHGDGVEXAFY 756
H +RV+ ID DVHHG+G AFY
Sbjct: 243 YAQNQHGLKRVMIIDFDVHHGNGTCDAFY 271
>UniRef50_A4BSQ6 Cluster: Histone deacetylase/AcuC/AphA family
protein; n=1; Nitrococcus mobilis Nb-231|Rep: Histone
deacetylase/AcuC/AphA family protein - Nitrococcus
mobilis Nb-231
Length = 327
Score = 44.4 bits (100), Expect = 0.003
Identities = 18/47 (38%), Positives = 30/47 (63%), Gaps = 2/47 (4%)
Frame = +1
Query: 610 HHAKKSEASGFCYVNDIVLGILEL-LKYHQR-VLYIDIDVHHGDGVE 744
HH++ + A GFC N++ +G L+ +Y R + +D DVHHG+G +
Sbjct: 144 HHSEPARAMGFCLFNNVAVGALQARCRYAARNIAVVDFDVHHGNGTQ 190
>UniRef50_A2WM81 Cluster: Putative uncharacterized protein; n=1;
Oryza sativa (indica cultivar-group)|Rep: Putative
uncharacterized protein - Oryza sativa subsp. indica
(Rice)
Length = 156
Score = 44.4 bits (100), Expect = 0.003
Identities = 28/88 (31%), Positives = 44/88 (50%), Gaps = 9/88 (10%)
Frame = +1
Query: 343 MEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVSE----YNKQMQRFNVG-----EDCP 495
M R T E+ +FH +YI +R++ P++ + K +G DCP
Sbjct: 1 MRRLRTSPTTEAEIRRFHLPEYIDLIRNLTPESYANDVVLRQKAEDDHGIGLLGDDNDCP 60
Query: 496 VFDGLYEFCQLSAGGSVAAAVKLNKQAS 579
F+ L+++C+ AGGS+AAA L AS
Sbjct: 61 AFNRLWKYCRGYAGGSLAAARALVNGAS 88
>UniRef50_Q0M412 Cluster: Histone deacetylase superfamily; n=1;
Caulobacter sp. K31|Rep: Histone deacetylase superfamily
- Caulobacter sp. K31
Length = 336
Score = 44.0 bits (99), Expect = 0.004
Identities = 42/163 (25%), Positives = 66/163 (40%), Gaps = 3/163 (1%)
Frame = +1
Query: 274 HPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDDYIRFLRSIRPDNVSEY 453
H +P R+R + L + + P AD + + HS +I + + P
Sbjct: 50 HAERPERLRAVIDALQDDACLDLESVEAPLIELAD-LARVHSQGFIDAILAAAPS----- 103
Query: 454 NKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAA--AVKLNKQASEICINWGGGLHHAKKS 627
R + D + G + +AG AA AV + C G HHA+
Sbjct: 104 ---AGRHALDPDTVLSTGSLIAARRAAGAVAAATRAVASGQGTRAFCAVRPPG-HHAEPG 159
Query: 628 EASGFCYVNDIVLGI-LELLKYHQRVLYIDIDVHHGDGVEXAF 753
A GFC ++I + + +RV +D DVHHG+G + AF
Sbjct: 160 VAMGFCVFSNIAVAARVAQASGLKRVAIVDFDVHHGNGTQAAF 202
>UniRef50_A3K7Q8 Cluster: Acetylpolyamine aminohydrolase; n=1;
Sagittula stellata E-37|Rep: Acetylpolyamine
aminohydrolase - Sagittula stellata E-37
Length = 326
Score = 44.0 bits (99), Expect = 0.004
Identities = 19/56 (33%), Positives = 27/56 (48%)
Frame = +1
Query: 610 HHAKKSEASGFCYVNDIVLGILELLKYHQRVLYIDIDVHHGDGVEXAFYTTDRVMT 777
HHA G Y+N+ L + RV +DID HHG+G + F+ V+T
Sbjct: 144 HHASADLMGGTSYLNNAALAAAWMANQGARVATVDIDAHHGNGTQSVFWARGDVLT 199
>UniRef50_A4S240 Cluster: Predicted protein; n=2; Ostreococcus|Rep:
Predicted protein - Ostreococcus lucimarinus CCE9901
Length = 399
Score = 44.0 bits (99), Expect = 0.004
Identities = 22/56 (39%), Positives = 27/56 (48%), Gaps = 1/56 (1%)
Frame = +1
Query: 610 HHAKKSEASGFCYVNDIVLGILEL-LKYHQRVLYIDIDVHHGDGVEXAFYTTDRVM 774
HHA A GFC V L+ H++VL D DVHHG+G F D V+
Sbjct: 180 HHAVPRGAMGFCLVGTAAAAARHAQLRGHKKVLIFDYDVHHGNGTNDIFRDDDSVL 235
>UniRef50_Q1DM14 Cluster: Putative uncharacterized protein; n=1;
Coccidioides immitis|Rep: Putative uncharacterized
protein - Coccidioides immitis
Length = 1084
Score = 44.0 bits (99), Expect = 0.004
Identities = 21/54 (38%), Positives = 29/54 (53%), Gaps = 2/54 (3%)
Frame = +1
Query: 583 ICINWGGGLHHAKKSEASGFCYVNDIVLGILELLKYH--QRVLYIDIDVHHGDG 738
+CI G HH + SGFC++N++ +GI H ID D+HHGDG
Sbjct: 354 VCIRPPG--HHCSSNFPSGFCWLNNVHVGIAHAAMTHGLTHAAIIDFDLHHGDG 405
>UniRef50_Q12A19 Cluster: Histone deacetylase superfamily; n=4;
Proteobacteria|Rep: Histone deacetylase superfamily -
Polaromonas sp. (strain JS666 / ATCC BAA-500)
Length = 359
Score = 43.6 bits (98), Expect = 0.006
Identities = 37/139 (26%), Positives = 62/139 (44%), Gaps = 8/139 (5%)
Frame = +1
Query: 364 KATADEMTKFHSDDYIRFLRS-IRPDNVSEYNKQMQRFNVGEDCPVFDGLYEFCQLSAGG 540
+A D+ F S +R LRS + P N + ++ +++ P+ G + + A
Sbjct: 91 EAGNDQRQPFPSVWPVRTLRSDVEPVN---FIARLGLYSMDNGSPLAAGTWTAAKAGADA 147
Query: 541 SVAAAVKL------NKQASEICINWGGGLHHAKKSEASGFCYVNDIVLGILELLKYHQ-R 699
+ +AA L +QA C G HHA G+C++N+ + L R
Sbjct: 148 AASAAALLAVGGRRGEQAVFCCSRPPG--HHAGPDFMGGYCFLNNAAVAAQALRDGGAAR 205
Query: 700 VLYIDIDVHHGDGVEXAFY 756
V +D+D HHG+G + FY
Sbjct: 206 VAVLDVDYHHGNGTQSIFY 224
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 715,161,992
Number of Sequences: 1657284
Number of extensions: 14012598
Number of successful extensions: 32654
Number of sequences better than 10.0: 308
Number of HSP's better than 10.0 without gapping: 31296
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 32321
length of database: 575,637,011
effective HSP length: 99
effective length of database: 411,565,895
effective search space used: 65438977305
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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