Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P14_pT_M20
(472 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X57778-1|CAA40924.1| 359|Homo sapiens E-1 beta subunit of the p... 149 6e-36
M54788-1|AAA60053.1| 359|Homo sapiens pyruvate dehydrogenase E1... 149 6e-36
M34479-1|AAA36428.1| 359|Homo sapiens pyruvate dehydrogenase be... 149 6e-36
M34056-1|AAA60054.1| 335|Homo sapiens PDHB protein. 149 6e-36
M34055-1|AAA60233.1| 359|Homo sapiens PDHB protein. 149 6e-36
J03576-1|AAA88097.1| 359|Homo sapiens pyruvate dehydrogenase be... 149 6e-36
D90086-1|BAA14123.1| 359|Homo sapiens pyruvate dehydrogenase be... 149 6e-36
CR541911-1|CAG46709.1| 359|Homo sapiens PDHB protein. 149 6e-36
BC001924-1|AAH01924.1| 359|Homo sapiens pyruvate dehydrogenase ... 149 6e-36
BC000439-1|AAH00439.1| 359|Homo sapiens pyruvate dehydrogenase ... 149 6e-36
U50708-1|AAB16763.1| 392|Homo sapiens branched chain alpha-keto... 77 2e-14
M55575-1|AAA51812.1| 392|Homo sapiens branched chain alpha-keto... 77 2e-14
D90391-1|BAA14389.1| 392|Homo sapiens E-1-beta subunit of branc... 77 2e-14
BT020063-1|AAV38866.1| 392|Homo sapiens branched chain keto aci... 77 2e-14
BC040139-1|AAH40139.1| 392|Homo sapiens branched chain keto aci... 77 2e-14
AL391595-1|CAI15049.1| 392|Homo sapiens branched chain keto aci... 77 2e-14
AL049696-1|CAC36881.2| 392|Homo sapiens branched chain keto aci... 77 2e-14
X52446-1|CAA36685.1| 373|Homo sapiens protein ( Human mRNA for ... 76 7e-14
Z49258-5|CAI39236.1| 146|Homo sapiens transketolase-like 1 prot... 54 2e-07
Z49258-4|CAH69900.1| 540|Homo sapiens transketolase-like 1 prot... 54 2e-07
Z49258-1|CAH69899.1| 596|Homo sapiens transketolase-like 1 prot... 54 2e-07
X91817-1|CAA62925.1| 557|Homo sapiens transketolase protein. 54 2e-07
BC025382-1|AAH25382.2| 596|Homo sapiens transketolase-like 1 pr... 54 2e-07
CR533560-1|CAG38591.1| 626|Homo sapiens DKFZP434L1717 protein. 51 2e-06
BC142943-1|AAI42944.1| 626|Homo sapiens transketolase-like 2 pr... 51 2e-06
BC125101-1|AAI25102.1| 626|Homo sapiens transketolase-like 2 pr... 51 2e-06
BC028707-1|AAH28707.4| 626|Homo sapiens transketolase-like 2 pr... 51 2e-06
AK057537-1|BAB71524.1| 320|Homo sapiens protein ( Homo sapiens ... 51 2e-06
AK057325-1|BAB71427.1| 626|Homo sapiens protein ( Homo sapiens ... 51 2e-06
X67688-1|CAA47919.1| 623|Homo sapiens transketolase protein. 38 0.013
U55017-1|AAA98961.1| 623|Homo sapiens transketolase protein. 38 0.013
BC024026-1|AAH24026.2| 536|Homo sapiens TKT protein protein. 38 0.013
BC009970-1|AAH09970.1| 623|Homo sapiens transketolase (Wernicke... 38 0.013
BC008615-1|AAH08615.1| 395|Homo sapiens Similar to transketolas... 38 0.013
BC002433-1|AAH02433.1| 457|Homo sapiens TKT protein protein. 38 0.013
AK223614-1|BAD97334.1| 623|Homo sapiens transketolase variant p... 38 0.013
L12711-1|AAA61222.1| 623|Homo sapiens transketolase protein. 38 0.018
U51015-1|AAB09779.1| 46|Homo sapiens branched chain alpha-keto... 31 2.0
Y08266-1|CAA69592.1| 191|Homo sapiens DAN15 protein. 29 6.1
>X57778-1|CAA40924.1| 359|Homo sapiens E-1 beta subunit of the
pyruvate dehydrogenase complex protein.
Length = 359
Score = 149 bits (360), Expect = 6e-36
Identities = 69/112 (61%), Positives = 85/112 (75%)
Frame = -2
Query: 471 KVEREGRHITXVCAGRGTDTALKAAEQLAGSKGIECEVVNLRTIRPMDFDTIARSIAKTH 292
K+ER+G HIT V R L+AA L+ +G+ECEV+N+RTIRPMD +TI S+ KT+
Sbjct: 229 KIERQGTHITVVSHSRPVGHCLEAAAVLS-KEGVECEVINMRTIRPMDMETIEASVMKTN 287
Query: 291 HLITVEQGWPQSGIGAEICARVMESPSFFELDAPVWRVCGADVPMPYARTLE 136
HL+TVE GWPQ G+GAEICAR+ME P+F LDAP RV GADVPMPYA+ LE
Sbjct: 288 HLVTVEGGWPQFGVGAEICARIMEGPAFNFLDAPAVRVTGADVPMPYAKILE 339
>M54788-1|AAA60053.1| 359|Homo sapiens pyruvate dehydrogenase
E1-beta subunit protein.
Length = 359
Score = 149 bits (360), Expect = 6e-36
Identities = 69/112 (61%), Positives = 85/112 (75%)
Frame = -2
Query: 471 KVEREGRHITXVCAGRGTDTALKAAEQLAGSKGIECEVVNLRTIRPMDFDTIARSIAKTH 292
K+ER+G HIT V R L+AA L+ +G+ECEV+N+RTIRPMD +TI S+ KT+
Sbjct: 229 KIERQGTHITVVSHSRPVGHCLEAAAVLS-KEGVECEVINMRTIRPMDMETIEASVMKTN 287
Query: 291 HLITVEQGWPQSGIGAEICARVMESPSFFELDAPVWRVCGADVPMPYARTLE 136
HL+TVE GWPQ G+GAEICAR+ME P+F LDAP RV GADVPMPYA+ LE
Sbjct: 288 HLVTVEGGWPQFGVGAEICARIMEGPAFNFLDAPAVRVTGADVPMPYAKILE 339
>M34479-1|AAA36428.1| 359|Homo sapiens pyruvate dehydrogenase
beta-subunit protein.
Length = 359
Score = 149 bits (360), Expect = 6e-36
Identities = 69/112 (61%), Positives = 85/112 (75%)
Frame = -2
Query: 471 KVEREGRHITXVCAGRGTDTALKAAEQLAGSKGIECEVVNLRTIRPMDFDTIARSIAKTH 292
K+ER+G HIT V R L+AA L+ +G+ECEV+N+RTIRPMD +TI S+ KT+
Sbjct: 229 KIERQGTHITVVSHSRPVGHCLEAAAVLS-KEGVECEVINMRTIRPMDMETIEASVMKTN 287
Query: 291 HLITVEQGWPQSGIGAEICARVMESPSFFELDAPVWRVCGADVPMPYARTLE 136
HL+TVE GWPQ G+GAEICAR+ME P+F LDAP RV GADVPMPYA+ LE
Sbjct: 288 HLVTVEGGWPQFGVGAEICARIMEGPAFNFLDAPAVRVTGADVPMPYAKILE 339
>M34056-1|AAA60054.1| 335|Homo sapiens PDHB protein.
Length = 335
Score = 149 bits (360), Expect = 6e-36
Identities = 69/112 (61%), Positives = 85/112 (75%)
Frame = -2
Query: 471 KVEREGRHITXVCAGRGTDTALKAAEQLAGSKGIECEVVNLRTIRPMDFDTIARSIAKTH 292
K+ER+G HIT V R L+AA L+ +G+ECEV+N+RTIRPMD +TI S+ KT+
Sbjct: 205 KIERQGTHITVVSHSRPVGHCLEAAAVLS-KEGVECEVINMRTIRPMDMETIEASVMKTN 263
Query: 291 HLITVEQGWPQSGIGAEICARVMESPSFFELDAPVWRVCGADVPMPYARTLE 136
HL+TVE GWPQ G+GAEICAR+ME P+F LDAP RV GADVPMPYA+ LE
Sbjct: 264 HLVTVEGGWPQFGVGAEICARIMEGPAFNFLDAPAVRVTGADVPMPYAKILE 315
>M34055-1|AAA60233.1| 359|Homo sapiens PDHB protein.
Length = 359
Score = 149 bits (360), Expect = 6e-36
Identities = 69/112 (61%), Positives = 85/112 (75%)
Frame = -2
Query: 471 KVEREGRHITXVCAGRGTDTALKAAEQLAGSKGIECEVVNLRTIRPMDFDTIARSIAKTH 292
K+ER+G HIT V R L+AA L+ +G+ECEV+N+RTIRPMD +TI S+ KT+
Sbjct: 229 KIERQGTHITVVSHSRPVGHCLEAAAVLS-KEGVECEVINMRTIRPMDMETIEASVMKTN 287
Query: 291 HLITVEQGWPQSGIGAEICARVMESPSFFELDAPVWRVCGADVPMPYARTLE 136
HL+TVE GWPQ G+GAEICAR+ME P+F LDAP RV GADVPMPYA+ LE
Sbjct: 288 HLVTVEGGWPQFGVGAEICARIMEGPAFNFLDAPAVRVTGADVPMPYAKILE 339
>J03576-1|AAA88097.1| 359|Homo sapiens pyruvate dehydrogenase beta
subunit protein.
Length = 359
Score = 149 bits (360), Expect = 6e-36
Identities = 69/112 (61%), Positives = 85/112 (75%)
Frame = -2
Query: 471 KVEREGRHITXVCAGRGTDTALKAAEQLAGSKGIECEVVNLRTIRPMDFDTIARSIAKTH 292
K+ER+G HIT V R L+AA L+ +G+ECEV+N+RTIRPMD +TI S+ KT+
Sbjct: 229 KIERQGTHITVVSHSRPVGHCLEAAAVLS-KEGVECEVINMRTIRPMDMETIEASVMKTN 287
Query: 291 HLITVEQGWPQSGIGAEICARVMESPSFFELDAPVWRVCGADVPMPYARTLE 136
HL+TVE GWPQ G+GAEICAR+ME P+F LDAP RV GADVPMPYA+ LE
Sbjct: 288 HLVTVEGGWPQFGVGAEICARIMEGPAFNFLDAPAVRVTGADVPMPYAKILE 339
>D90086-1|BAA14123.1| 359|Homo sapiens pyruvate dehydrogenase beta
subunit protein.
Length = 359
Score = 149 bits (360), Expect = 6e-36
Identities = 69/112 (61%), Positives = 85/112 (75%)
Frame = -2
Query: 471 KVEREGRHITXVCAGRGTDTALKAAEQLAGSKGIECEVVNLRTIRPMDFDTIARSIAKTH 292
K+ER+G HIT V R L+AA L+ +G+ECEV+N+RTIRPMD +TI S+ KT+
Sbjct: 229 KIERQGTHITVVSHSRPVGHCLEAAAVLS-KEGVECEVINMRTIRPMDMETIEASVMKTN 287
Query: 291 HLITVEQGWPQSGIGAEICARVMESPSFFELDAPVWRVCGADVPMPYARTLE 136
HL+TVE GWPQ G+GAEICAR+ME P+F LDAP RV GADVPMPYA+ LE
Sbjct: 288 HLVTVEGGWPQFGVGAEICARIMEGPAFNFLDAPAVRVTGADVPMPYAKILE 339
>CR541911-1|CAG46709.1| 359|Homo sapiens PDHB protein.
Length = 359
Score = 149 bits (360), Expect = 6e-36
Identities = 69/112 (61%), Positives = 85/112 (75%)
Frame = -2
Query: 471 KVEREGRHITXVCAGRGTDTALKAAEQLAGSKGIECEVVNLRTIRPMDFDTIARSIAKTH 292
K+ER+G HIT V R L+AA L+ +G+ECEV+N+RTIRPMD +TI S+ KT+
Sbjct: 229 KIERQGTHITVVSHSRPVGHCLEAAAVLS-KEGVECEVINMRTIRPMDMETIEASVMKTN 287
Query: 291 HLITVEQGWPQSGIGAEICARVMESPSFFELDAPVWRVCGADVPMPYARTLE 136
HL+TVE GWPQ G+GAEICAR+ME P+F LDAP RV GADVPMPYA+ LE
Sbjct: 288 HLVTVEGGWPQFGVGAEICARIMEGPAFNFLDAPAVRVTGADVPMPYAKILE 339
>BC001924-1|AAH01924.1| 359|Homo sapiens pyruvate dehydrogenase
(lipoamide) beta protein.
Length = 359
Score = 149 bits (360), Expect = 6e-36
Identities = 69/112 (61%), Positives = 85/112 (75%)
Frame = -2
Query: 471 KVEREGRHITXVCAGRGTDTALKAAEQLAGSKGIECEVVNLRTIRPMDFDTIARSIAKTH 292
K+ER+G HIT V R L+AA L+ +G+ECEV+N+RTIRPMD +TI S+ KT+
Sbjct: 229 KIERQGTHITVVSHSRPVGHCLEAAAVLS-KEGVECEVINMRTIRPMDMETIEASVMKTN 287
Query: 291 HLITVEQGWPQSGIGAEICARVMESPSFFELDAPVWRVCGADVPMPYARTLE 136
HL+TVE GWPQ G+GAEICAR+ME P+F LDAP RV GADVPMPYA+ LE
Sbjct: 288 HLVTVEGGWPQFGVGAEICARIMEGPAFNFLDAPAVRVTGADVPMPYAKILE 339
>BC000439-1|AAH00439.1| 359|Homo sapiens pyruvate dehydrogenase
(lipoamide) beta protein.
Length = 359
Score = 149 bits (360), Expect = 6e-36
Identities = 69/112 (61%), Positives = 85/112 (75%)
Frame = -2
Query: 471 KVEREGRHITXVCAGRGTDTALKAAEQLAGSKGIECEVVNLRTIRPMDFDTIARSIAKTH 292
K+ER+G HIT V R L+AA L+ +G+ECEV+N+RTIRPMD +TI S+ KT+
Sbjct: 229 KIERQGTHITVVSHSRPVGHCLEAAAVLS-KEGVECEVINMRTIRPMDMETIEASVMKTN 287
Query: 291 HLITVEQGWPQSGIGAEICARVMESPSFFELDAPVWRVCGADVPMPYARTLE 136
HL+TVE GWPQ G+GAEICAR+ME P+F LDAP RV GADVPMPYA+ LE
Sbjct: 288 HLVTVEGGWPQFGVGAEICARIMEGPAFNFLDAPAVRVTGADVPMPYAKILE 339
>U50708-1|AAB16763.1| 392|Homo sapiens branched chain
alpha-ketoacid dehydrogenase E1 beta subunit protein.
Length = 392
Score = 77.4 bits (182), Expect = 2e-14
Identities = 40/107 (37%), Positives = 56/107 (52%)
Frame = -2
Query: 471 KVEREGRHITXVCAGRGTDTALKAAEQLAGSKGIECEVVNLRTIRPMDFDTIARSIAKTH 292
+V +EG +T V G + A G+ CEV++LRTI P D DTI +S+ KT
Sbjct: 264 EVIQEGSDVTLVAWGTQVHVIREVASMAKEKLGVSCEVIDLRTIIPWDVDTICKSVIKTG 323
Query: 291 HLITVEQGWPQSGIGAEICARVMESPSFFELDAPVWRVCGADVPMPY 151
L+ + G +EI + V E F L+AP+ RVCG D P P+
Sbjct: 324 RLLISHEAPLTGGFASEISSTVQEE-CFLNLEAPISRVCGYDTPFPH 369
>M55575-1|AAA51812.1| 392|Homo sapiens branched chain alpha-keto
acid dehydrogenase E1-beta subunit protein.
Length = 392
Score = 77.4 bits (182), Expect = 2e-14
Identities = 40/107 (37%), Positives = 56/107 (52%)
Frame = -2
Query: 471 KVEREGRHITXVCAGRGTDTALKAAEQLAGSKGIECEVVNLRTIRPMDFDTIARSIAKTH 292
+V +EG +T V G + A G+ CEV++LRTI P D DTI +S+ KT
Sbjct: 264 EVIQEGSDVTLVAWGTQVHVIREVASMAKEKLGVSCEVIDLRTIIPWDVDTICKSVIKTG 323
Query: 291 HLITVEQGWPQSGIGAEICARVMESPSFFELDAPVWRVCGADVPMPY 151
L+ + G +EI + V E F L+AP+ RVCG D P P+
Sbjct: 324 RLLISHEAPLTGGFASEISSTVQEE-CFLNLEAPISRVCGYDTPFPH 369
>D90391-1|BAA14389.1| 392|Homo sapiens E-1-beta subunit of branched
chain alpha-keto acid dehydrogenase protein.
Length = 392
Score = 77.4 bits (182), Expect = 2e-14
Identities = 40/107 (37%), Positives = 56/107 (52%)
Frame = -2
Query: 471 KVEREGRHITXVCAGRGTDTALKAAEQLAGSKGIECEVVNLRTIRPMDFDTIARSIAKTH 292
+V +EG +T V G + A G+ CEV++LRTI P D DTI +S+ KT
Sbjct: 264 EVIQEGSDVTLVAWGTQVHVIREVASMAKEKLGVSCEVIDLRTIIPWDVDTICKSVIKTG 323
Query: 291 HLITVEQGWPQSGIGAEICARVMESPSFFELDAPVWRVCGADVPMPY 151
L+ + G +EI + V E F L+AP+ RVCG D P P+
Sbjct: 324 RLLISHEAPLTGGFASEISSTVQEE-CFLNLEAPISRVCGYDTPFPH 369
>BT020063-1|AAV38866.1| 392|Homo sapiens branched chain keto acid
dehydrogenase E1, beta polypeptide (maple syrup urine
protein.
Length = 392
Score = 77.4 bits (182), Expect = 2e-14
Identities = 40/107 (37%), Positives = 56/107 (52%)
Frame = -2
Query: 471 KVEREGRHITXVCAGRGTDTALKAAEQLAGSKGIECEVVNLRTIRPMDFDTIARSIAKTH 292
+V +EG +T V G + A G+ CEV++LRTI P D DTI +S+ KT
Sbjct: 264 EVIQEGSDVTLVAWGTQVHVIREVASMAKEKLGVSCEVIDLRTIIPWDVDTICKSVIKTG 323
Query: 291 HLITVEQGWPQSGIGAEICARVMESPSFFELDAPVWRVCGADVPMPY 151
L+ + G +EI + V E F L+AP+ RVCG D P P+
Sbjct: 324 RLLISHEAPLTGGFASEISSTVQEE-CFLNLEAPISRVCGYDTPFPH 369
>BC040139-1|AAH40139.1| 392|Homo sapiens branched chain keto acid
dehydrogenase E1, beta polypeptide (maple syrup urine
protein.
Length = 392
Score = 77.4 bits (182), Expect = 2e-14
Identities = 40/107 (37%), Positives = 56/107 (52%)
Frame = -2
Query: 471 KVEREGRHITXVCAGRGTDTALKAAEQLAGSKGIECEVVNLRTIRPMDFDTIARSIAKTH 292
+V +EG +T V G + A G+ CEV++LRTI P D DTI +S+ KT
Sbjct: 264 EVIQEGSDVTLVAWGTQVHVIREVASMAKEKLGVSCEVIDLRTIIPWDVDTICKSVIKTG 323
Query: 291 HLITVEQGWPQSGIGAEICARVMESPSFFELDAPVWRVCGADVPMPY 151
L+ + G +EI + V E F L+AP+ RVCG D P P+
Sbjct: 324 RLLISHEAPLTGGFASEISSTVQEE-CFLNLEAPISRVCGYDTPFPH 369
>AL391595-1|CAI15049.1| 392|Homo sapiens branched chain keto acid
dehydrogenase E1, beta polypeptide (maple syrup urine
protein.
Length = 392
Score = 77.4 bits (182), Expect = 2e-14
Identities = 40/107 (37%), Positives = 56/107 (52%)
Frame = -2
Query: 471 KVEREGRHITXVCAGRGTDTALKAAEQLAGSKGIECEVVNLRTIRPMDFDTIARSIAKTH 292
+V +EG +T V G + A G+ CEV++LRTI P D DTI +S+ KT
Sbjct: 264 EVIQEGSDVTLVAWGTQVHVIREVASMAKEKLGVSCEVIDLRTIIPWDVDTICKSVIKTG 323
Query: 291 HLITVEQGWPQSGIGAEICARVMESPSFFELDAPVWRVCGADVPMPY 151
L+ + G +EI + V E F L+AP+ RVCG D P P+
Sbjct: 324 RLLISHEAPLTGGFASEISSTVQEE-CFLNLEAPISRVCGYDTPFPH 369
>AL049696-1|CAC36881.2| 392|Homo sapiens branched chain keto acid
dehydrogenase E1, beta polypeptide (maple syrup urine
protein.
Length = 392
Score = 77.4 bits (182), Expect = 2e-14
Identities = 40/107 (37%), Positives = 56/107 (52%)
Frame = -2
Query: 471 KVEREGRHITXVCAGRGTDTALKAAEQLAGSKGIECEVVNLRTIRPMDFDTIARSIAKTH 292
+V +EG +T V G + A G+ CEV++LRTI P D DTI +S+ KT
Sbjct: 264 EVIQEGSDVTLVAWGTQVHVIREVASMAKEKLGVSCEVIDLRTIIPWDVDTICKSVIKTG 323
Query: 291 HLITVEQGWPQSGIGAEICARVMESPSFFELDAPVWRVCGADVPMPY 151
L+ + G +EI + V E F L+AP+ RVCG D P P+
Sbjct: 324 RLLISHEAPLTGGFASEISSTVQEE-CFLNLEAPISRVCGYDTPFPH 369
>X52446-1|CAA36685.1| 373|Homo sapiens protein ( Human mRNA for
E1b-beta subunit of the branched-chain complex. ).
Length = 373
Score = 75.8 bits (178), Expect = 7e-14
Identities = 39/107 (36%), Positives = 56/107 (52%)
Frame = -2
Query: 471 KVEREGRHITXVCAGRGTDTALKAAEQLAGSKGIECEVVNLRTIRPMDFDTIARSIAKTH 292
+V +EG +T V G + A G+ CEV++LRTI P D DTI +S+ K+
Sbjct: 245 EVIQEGSDVTLVAWGTQVHVIREVASMAKEKLGVSCEVIDLRTIIPWDVDTICKSVIKSG 304
Query: 291 HLITVEQGWPQSGIGAEICARVMESPSFFELDAPVWRVCGADVPMPY 151
L+ + G +EI + V E F L+AP+ RVCG D P P+
Sbjct: 305 RLLISHEAPLTGGFASEISSTVQEE-CFLNLEAPISRVCGYDTPFPH 350
>Z49258-5|CAI39236.1| 146|Homo sapiens transketolase-like 1
protein.
Length = 146
Score = 54.4 bits (125), Expect = 2e-07
Identities = 32/79 (40%), Positives = 45/79 (56%), Gaps = 1/79 (1%)
Frame = -2
Query: 447 ITXVCAGRGTDTALKAAEQLAGSKGIECEVVNLRTIRPMDFDTIARSIAKTH-HLITVEQ 271
+T + AG AL AA++L+ + I V++L TI+P+D TI S T +ITVE
Sbjct: 27 VTVIGAGITVYEALAAADELS-KQDIFIRVIDLFTIKPLDVATIVSSAKATEGRIITVED 85
Query: 270 GWPQSGIGAEICARVMESP 214
+PQ GIG +CA V P
Sbjct: 86 HYPQGGIGEAVCAAVSMDP 104
>Z49258-4|CAH69900.1| 540|Homo sapiens transketolase-like 1
protein.
Length = 540
Score = 54.4 bits (125), Expect = 2e-07
Identities = 32/79 (40%), Positives = 45/79 (56%), Gaps = 1/79 (1%)
Frame = -2
Query: 447 ITXVCAGRGTDTALKAAEQLAGSKGIECEVVNLRTIRPMDFDTIARSIAKTH-HLITVEQ 271
+T + AG AL AA++L+ + I V++L TI+P+D TI S T +ITVE
Sbjct: 421 VTVIGAGITVYEALAAADELS-KQDIFIRVIDLFTIKPLDVATIVSSAKATEGRIITVED 479
Query: 270 GWPQSGIGAEICARVMESP 214
+PQ GIG +CA V P
Sbjct: 480 HYPQGGIGEAVCAAVSMDP 498
>Z49258-1|CAH69899.1| 596|Homo sapiens transketolase-like 1
protein.
Length = 596
Score = 54.4 bits (125), Expect = 2e-07
Identities = 32/79 (40%), Positives = 45/79 (56%), Gaps = 1/79 (1%)
Frame = -2
Query: 447 ITXVCAGRGTDTALKAAEQLAGSKGIECEVVNLRTIRPMDFDTIARSIAKTH-HLITVEQ 271
+T + AG AL AA++L+ + I V++L TI+P+D TI S T +ITVE
Sbjct: 477 VTVIGAGITVYEALAAADELS-KQDIFIRVIDLFTIKPLDVATIVSSAKATEGRIITVED 535
Query: 270 GWPQSGIGAEICARVMESP 214
+PQ GIG +CA V P
Sbjct: 536 HYPQGGIGEAVCAAVSMDP 554
>X91817-1|CAA62925.1| 557|Homo sapiens transketolase protein.
Length = 557
Score = 54.4 bits (125), Expect = 2e-07
Identities = 32/79 (40%), Positives = 45/79 (56%), Gaps = 1/79 (1%)
Frame = -2
Query: 447 ITXVCAGRGTDTALKAAEQLAGSKGIECEVVNLRTIRPMDFDTIARSIAKTH-HLITVEQ 271
+T + AG AL AA++L+ + I V++L TI+P+D TI S T +ITVE
Sbjct: 438 VTVIGAGITVYEALAAADELS-KQDIFIRVIDLFTIKPLDVATIVSSAKATEGRIITVED 496
Query: 270 GWPQSGIGAEICARVMESP 214
+PQ GIG +CA V P
Sbjct: 497 HYPQGGIGEAVCAAVSMDP 515
>BC025382-1|AAH25382.2| 596|Homo sapiens transketolase-like 1
protein.
Length = 596
Score = 54.4 bits (125), Expect = 2e-07
Identities = 32/79 (40%), Positives = 45/79 (56%), Gaps = 1/79 (1%)
Frame = -2
Query: 447 ITXVCAGRGTDTALKAAEQLAGSKGIECEVVNLRTIRPMDFDTIARSIAKTH-HLITVEQ 271
+T + AG AL AA++L+ + I V++L TI+P+D TI S T +ITVE
Sbjct: 477 VTVIGAGITVYEALAAADELS-KQDIFIRVIDLFTIKPLDVATIVSSAKATEGRIITVED 535
Query: 270 GWPQSGIGAEICARVMESP 214
+PQ GIG +CA V P
Sbjct: 536 HYPQGGIGEAVCAAVSMDP 554
>CR533560-1|CAG38591.1| 626|Homo sapiens DKFZP434L1717 protein.
Length = 626
Score = 51.2 bits (117), Expect = 2e-06
Identities = 34/89 (38%), Positives = 49/89 (55%), Gaps = 3/89 (3%)
Frame = -2
Query: 471 KVEREGRH--ITXVCAGRGTDTALKAAEQLAGSKGIECEVVNLRTIRPMDFDTIARSIAK 298
KV R G + +T + AG AL+AA+ L+ +GI V++ TI+P+D TI S
Sbjct: 497 KVVRHGVNDKVTVIGAGVTLHEALEAADHLS-QQGISVRVIDPFTIKPLDAATIISSAKA 555
Query: 297 TH-HLITVEQGWPQSGIGAEICARVMESP 214
T +ITVE + + GIG +CA V P
Sbjct: 556 TGGRVITVEDHYREGGIGEAVCAAVSREP 584
>BC142943-1|AAI42944.1| 626|Homo sapiens transketolase-like 2
protein.
Length = 626
Score = 51.2 bits (117), Expect = 2e-06
Identities = 34/89 (38%), Positives = 49/89 (55%), Gaps = 3/89 (3%)
Frame = -2
Query: 471 KVEREGRH--ITXVCAGRGTDTALKAAEQLAGSKGIECEVVNLRTIRPMDFDTIARSIAK 298
KV R G + +T + AG AL+AA+ L+ +GI V++ TI+P+D TI S
Sbjct: 497 KVVRHGVNDKVTVIGAGVTLHEALEAADHLS-QQGISVRVIDPFTIKPLDAATIISSAKA 555
Query: 297 TH-HLITVEQGWPQSGIGAEICARVMESP 214
T +ITVE + + GIG +CA V P
Sbjct: 556 TGGRVITVEDHYREGGIGEAVCAAVSREP 584
>BC125101-1|AAI25102.1| 626|Homo sapiens transketolase-like 2
protein.
Length = 626
Score = 51.2 bits (117), Expect = 2e-06
Identities = 34/89 (38%), Positives = 49/89 (55%), Gaps = 3/89 (3%)
Frame = -2
Query: 471 KVEREGRH--ITXVCAGRGTDTALKAAEQLAGSKGIECEVVNLRTIRPMDFDTIARSIAK 298
KV R G + +T + AG AL+AA+ L+ +GI V++ TI+P+D TI S
Sbjct: 497 KVVRHGVNDKVTVIGAGVTLHEALEAADHLS-QQGISVRVIDPFTIKPLDAATIISSAKA 555
Query: 297 TH-HLITVEQGWPQSGIGAEICARVMESP 214
T +ITVE + + GIG +CA V P
Sbjct: 556 TGGRVITVEDHYREGGIGEAVCAAVSREP 584
>BC028707-1|AAH28707.4| 626|Homo sapiens transketolase-like 2
protein.
Length = 626
Score = 51.2 bits (117), Expect = 2e-06
Identities = 34/89 (38%), Positives = 49/89 (55%), Gaps = 3/89 (3%)
Frame = -2
Query: 471 KVEREGRH--ITXVCAGRGTDTALKAAEQLAGSKGIECEVVNLRTIRPMDFDTIARSIAK 298
KV R G + +T + AG AL+AA+ L+ +GI V++ TI+P+D TI S
Sbjct: 497 KVVRHGVNDKVTVIGAGVTLHEALEAADHLS-QQGISVRVIDPFTIKPLDAATIISSAKA 555
Query: 297 TH-HLITVEQGWPQSGIGAEICARVMESP 214
T +ITVE + + GIG +CA V P
Sbjct: 556 TGGRVITVEDHYREGGIGEAVCAAVSREP 584
>AK057537-1|BAB71524.1| 320|Homo sapiens protein ( Homo sapiens
cDNA FLJ32975 fis, clone TESTI2013832, moderately
similar to Xenopus laevis transketolase mRNA. ).
Length = 320
Score = 51.2 bits (117), Expect = 2e-06
Identities = 34/89 (38%), Positives = 49/89 (55%), Gaps = 3/89 (3%)
Frame = -2
Query: 471 KVEREGRH--ITXVCAGRGTDTALKAAEQLAGSKGIECEVVNLRTIRPMDFDTIARSIAK 298
KV R G + +T + AG AL+AA+ L+ +GI V++ TI+P+D TI S
Sbjct: 191 KVVRHGVNDKVTVIGAGVTLHEALEAADHLS-QQGISVRVIDPFTIKPLDAATIISSAKA 249
Query: 297 TH-HLITVEQGWPQSGIGAEICARVMESP 214
T +ITVE + + GIG +CA V P
Sbjct: 250 TGGRVITVEDHYREGGIGEAVCAAVSREP 278
>AK057325-1|BAB71427.1| 626|Homo sapiens protein ( Homo sapiens
cDNA FLJ32763 fis, clone TESTI2001827, moderately
similar to TRANSKETOLASE (EC 2.2.1.1). ).
Length = 626
Score = 51.2 bits (117), Expect = 2e-06
Identities = 34/89 (38%), Positives = 49/89 (55%), Gaps = 3/89 (3%)
Frame = -2
Query: 471 KVEREGRH--ITXVCAGRGTDTALKAAEQLAGSKGIECEVVNLRTIRPMDFDTIARSIAK 298
KV R G + +T + AG AL+AA+ L+ +GI V++ TI+P+D TI S
Sbjct: 497 KVVRHGVNDKVTVIGAGVTLHEALEAADHLS-QQGISVRVIDPFTIKPLDAATIISSAKA 555
Query: 297 TH-HLITVEQGWPQSGIGAEICARVMESP 214
T +ITVE + + GIG +CA V P
Sbjct: 556 TGGRVITVEDHYREGGIGEAVCAAVSREP 584
>X67688-1|CAA47919.1| 623|Homo sapiens transketolase protein.
Length = 623
Score = 38.3 bits (85), Expect = 0.013
Identities = 30/91 (32%), Positives = 43/91 (47%), Gaps = 1/91 (1%)
Frame = -2
Query: 447 ITXVCAGRGTDTALKAAEQLAGSKGIECEVVNLRTIRPMDFDTIARSIAKTH-HLITVEQ 271
+T + AG AL AAE L K I V++ TI+P+D I S T ++TVE
Sbjct: 503 VTVIGAGVTLHEALAAAELLKKEK-INIRVLDPFTIKPLDRKLILDSARATKGRILTVED 561
Query: 270 GWPQSGIGAEICARVMESPSFFELDAPVWRV 178
+ + GIG + + V+ P V RV
Sbjct: 562 HYYEGGIGEAVSSAVVGEPGITVTHLAVNRV 592
>U55017-1|AAA98961.1| 623|Homo sapiens transketolase protein.
Length = 623
Score = 38.3 bits (85), Expect = 0.013
Identities = 30/91 (32%), Positives = 43/91 (47%), Gaps = 1/91 (1%)
Frame = -2
Query: 447 ITXVCAGRGTDTALKAAEQLAGSKGIECEVVNLRTIRPMDFDTIARSIAKTH-HLITVEQ 271
+T + AG AL AAE L K I V++ TI+P+D I S T ++TVE
Sbjct: 503 VTVIGAGVTLHEALAAAELLKKEK-INIRVLDPFTIKPLDRKLILDSARATKGRILTVED 561
Query: 270 GWPQSGIGAEICARVMESPSFFELDAPVWRV 178
+ + GIG + + V+ P V RV
Sbjct: 562 HYYEGGIGEAVSSAVVGEPGITVTHLAVNRV 592
>BC024026-1|AAH24026.2| 536|Homo sapiens TKT protein protein.
Length = 536
Score = 38.3 bits (85), Expect = 0.013
Identities = 30/91 (32%), Positives = 43/91 (47%), Gaps = 1/91 (1%)
Frame = -2
Query: 447 ITXVCAGRGTDTALKAAEQLAGSKGIECEVVNLRTIRPMDFDTIARSIAKTH-HLITVEQ 271
+T + AG AL AAE L K I V++ TI+P+D I S T ++TVE
Sbjct: 416 VTVIGAGVTLHEALAAAELLKKEK-INIRVLDPFTIKPLDRKLILDSARATKGRILTVED 474
Query: 270 GWPQSGIGAEICARVMESPSFFELDAPVWRV 178
+ + GIG + + V+ P V RV
Sbjct: 475 HYYEGGIGEAVSSAVVGEPGITVTHLAVNRV 505
>BC009970-1|AAH09970.1| 623|Homo sapiens transketolase
(Wernicke-Korsakoff syndrome) protein.
Length = 623
Score = 38.3 bits (85), Expect = 0.013
Identities = 30/91 (32%), Positives = 43/91 (47%), Gaps = 1/91 (1%)
Frame = -2
Query: 447 ITXVCAGRGTDTALKAAEQLAGSKGIECEVVNLRTIRPMDFDTIARSIAKTH-HLITVEQ 271
+T + AG AL AAE L K I V++ TI+P+D I S T ++TVE
Sbjct: 503 VTVIGAGVTLHEALAAAELLKKEK-INIRVLDPFTIKPLDRKLILDSARATKGRILTVED 561
Query: 270 GWPQSGIGAEICARVMESPSFFELDAPVWRV 178
+ + GIG + + V+ P V RV
Sbjct: 562 HYYEGGIGEAVSSAVVGEPGITVTHLAVNRV 592
>BC008615-1|AAH08615.1| 395|Homo sapiens Similar to transketolase
(Wernicke-Korsakoff syndrome) protein.
Length = 395
Score = 38.3 bits (85), Expect = 0.013
Identities = 30/91 (32%), Positives = 43/91 (47%), Gaps = 1/91 (1%)
Frame = -2
Query: 447 ITXVCAGRGTDTALKAAEQLAGSKGIECEVVNLRTIRPMDFDTIARSIAKTH-HLITVEQ 271
+T + AG AL AAE L K I V++ TI+P+D I S T ++TVE
Sbjct: 275 VTVIGAGVTLHEALAAAELLKKEK-INIRVLDPFTIKPLDRKLILDSARATKGRILTVED 333
Query: 270 GWPQSGIGAEICARVMESPSFFELDAPVWRV 178
+ + GIG + + V+ P V RV
Sbjct: 334 HYYEGGIGEAVSSAVVGEPGITVTHLAVNRV 364
>BC002433-1|AAH02433.1| 457|Homo sapiens TKT protein protein.
Length = 457
Score = 38.3 bits (85), Expect = 0.013
Identities = 30/91 (32%), Positives = 43/91 (47%), Gaps = 1/91 (1%)
Frame = -2
Query: 447 ITXVCAGRGTDTALKAAEQLAGSKGIECEVVNLRTIRPMDFDTIARSIAKTH-HLITVEQ 271
+T + AG AL AAE L K I V++ TI+P+D I S T ++TVE
Sbjct: 337 VTVIGAGVTLHEALAAAELLKKEK-INIRVLDPFTIKPLDRKLILDSARATKGRILTVED 395
Query: 270 GWPQSGIGAEICARVMESPSFFELDAPVWRV 178
+ + GIG + + V+ P V RV
Sbjct: 396 HYYEGGIGEAVSSAVVGEPGITVTHLAVNRV 426
>AK223614-1|BAD97334.1| 623|Homo sapiens transketolase variant
protein.
Length = 623
Score = 38.3 bits (85), Expect = 0.013
Identities = 30/91 (32%), Positives = 43/91 (47%), Gaps = 1/91 (1%)
Frame = -2
Query: 447 ITXVCAGRGTDTALKAAEQLAGSKGIECEVVNLRTIRPMDFDTIARSIAKTH-HLITVEQ 271
+T + AG AL AAE L K I V++ TI+P+D I S T ++TVE
Sbjct: 503 VTVIGAGVTLHEALAAAELLKKEK-INIRVLDPFTIKPLDRKLILDSARATKGRILTVED 561
Query: 270 GWPQSGIGAEICARVMESPSFFELDAPVWRV 178
+ + GIG + + V+ P V RV
Sbjct: 562 HYYEGGIGEAVSSAVVGEPGITVTHLAVNRV 592
>L12711-1|AAA61222.1| 623|Homo sapiens transketolase protein.
Length = 623
Score = 37.9 bits (84), Expect = 0.018
Identities = 27/79 (34%), Positives = 40/79 (50%), Gaps = 1/79 (1%)
Frame = -2
Query: 447 ITXVCAGRGTDTALKAAEQLAGSKGIECEVVNLRTIRPMDFDTIARSIAKTH-HLITVEQ 271
+T + AG AL AAE L K I V++ TI+P+D I S T ++TVE
Sbjct: 503 VTVIGAGVTLHEALAAAELLKKEK-INIRVLDPFTIKPLDRKLILDSARATKGRILTVED 561
Query: 270 GWPQSGIGAEICARVMESP 214
+ + GIG + + V+ P
Sbjct: 562 HYYEGGIGEAVSSAVVGEP 580
>U51015-1|AAB09779.1| 46|Homo sapiens branched chain
alpha-ketoacid dehydrogenase E1-beta subunit protein.
Length = 46
Score = 31.1 bits (67), Expect = 2.0
Identities = 11/20 (55%), Positives = 14/20 (70%)
Frame = -2
Query: 210 FFELDAPVWRVCGADVPMPY 151
F L+AP+ RVCG D P P+
Sbjct: 4 FLNLEAPISRVCGYDTPFPH 23
>Y08266-1|CAA69592.1| 191|Homo sapiens DAN15 protein.
Length = 191
Score = 29.5 bits (63), Expect = 6.1
Identities = 14/40 (35%), Positives = 20/40 (50%), Gaps = 2/40 (5%)
Frame = -1
Query: 301 QNTSSHYCRTRMAAIWNRRRDLRPRHGVAVVLR--ARCAG 188
Q +SH+ + ++ RR RPRHG A R +C G
Sbjct: 121 QQQTSHFQQQQLGRRGRRRASARPRHGAAATWRRQGQCCG 160
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 56,554,774
Number of Sequences: 237096
Number of extensions: 963135
Number of successful extensions: 2139
Number of sequences better than 10.0: 39
Number of HSP's better than 10.0 without gapping: 2074
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2121
length of database: 76,859,062
effective HSP length: 84
effective length of database: 56,942,998
effective search space used: 4099895856
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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