Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P14_pT_B02
(719 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
M24194-1|AAA59626.1| 317|Homo sapiens MHC B complex protein 12.... 351 1e-96
CR541909-1|CAG46707.1| 317|Homo sapiens GNB2L1 protein. 351 1e-96
CR456978-1|CAG33259.1| 317|Homo sapiens GNB2L1 protein. 351 1e-96
BC032006-1|AAH32006.1| 317|Homo sapiens guanine nucleotide bind... 351 1e-96
BC021993-1|AAH21993.1| 317|Homo sapiens guanine nucleotide bind... 351 1e-96
BC019362-1|AAH19362.1| 317|Homo sapiens guanine nucleotide bind... 351 1e-96
BC019093-1|AAH19093.1| 317|Homo sapiens guanine nucleotide bind... 351 1e-96
BC017287-1|AAH17287.1| 317|Homo sapiens guanine nucleotide bind... 351 1e-96
BC014788-1|AAH14788.1| 317|Homo sapiens guanine nucleotide bind... 351 1e-96
BC014256-1|AAH14256.1| 317|Homo sapiens guanine nucleotide bind... 351 1e-96
BC010119-1|AAH10119.1| 317|Homo sapiens guanine nucleotide bind... 351 1e-96
BC000366-1|AAH00366.1| 317|Homo sapiens guanine nucleotide bind... 351 1e-96
BC000214-1|AAH00214.1| 317|Homo sapiens guanine nucleotide bind... 351 1e-96
AY336089-1|AAR24619.1| 271|Homo sapiens proliferation-inducing ... 351 1e-96
AY159316-1|AAO21313.1| 347|Homo sapiens lung cancer oncogene 7 ... 351 1e-96
AK222488-1|BAD96208.1| 317|Homo sapiens guanine nucleotide bind... 349 4e-96
AK002149-1|BAA92110.1| 330|Homo sapiens protein ( Homo sapiens ... 93 1e-18
CR457279-1|CAG33560.1| 330|Homo sapiens WDR5B protein. 92 2e-18
BC043494-1|AAH43494.1| 330|Homo sapiens WD repeat domain 5B pro... 92 2e-18
BX649632-1|CAI18774.1| 334|Homo sapiens WD repeat domain 5 prot... 90 8e-18
BC001635-1|AAH01635.1| 334|Homo sapiens WD repeat domain 5 prot... 90 8e-18
AK000552-1|BAA91248.1| 334|Homo sapiens protein ( Homo sapiens ... 90 8e-18
AJ011376-1|CAB66159.1| 362|Homo sapiens hypothetical protein pr... 90 8e-18
EF011619-1|ABK41109.1| 478|Homo sapiens CDW9/WDR51B protein. 89 1e-17
BC026080-1|AAH26080.1| 478|Homo sapiens WD repeat domain 51B pr... 89 1e-17
AK074772-1|BAC11198.1| 478|Homo sapiens protein ( Homo sapiens ... 89 1e-17
BC119693-1|AAI19694.1| 441|Homo sapiens WDR51A protein protein. 83 7e-16
BC119692-1|AAI19693.1| 407|Homo sapiens WD repeat domain 51A pr... 83 7e-16
BC110877-1|AAI10878.1| 359|Homo sapiens WDR51A protein protein. 83 7e-16
BC007417-1|AAH07417.2| 396|Homo sapiens WDR51A protein protein. 83 7e-16
AK075289-1|BAC11525.1| 407|Homo sapiens protein ( Homo sapiens ... 83 1e-15
BT009800-1|AAP88802.1| 340|Homo sapiens guanine nucleotide bind... 83 1e-15
BC002454-1|AAH02454.1| 340|Homo sapiens guanine nucleotide bind... 83 1e-15
BC000115-1|AAH00115.1| 340|Homo sapiens guanine nucleotide bind... 83 1e-15
Y12050-1|CAA72779.1| 340|Homo sapiens guanine nucleotide-bindin... 81 3e-15
U47924-5|AAB51313.1| 340|Homo sapiens G-protein beta-3 chain pr... 81 3e-15
M31328-1|AAA52582.1| 340|Homo sapiens GNB3 protein. 81 3e-15
BC127949-1|AAI27950.1| 314|Homo sapiens WD repeat domain 38 pro... 81 3e-15
AY631872-1|AAT38116.1| 340|Homo sapiens guanine nucleotide bind... 81 3e-15
AF501884-1|AAM15920.1| 340|Homo sapiens guanine nucleotide bind... 81 3e-15
AB209283-1|BAD92520.1| 327|Homo sapiens guanine nucleotide-bind... 81 3e-15
AB053276-1|BAB69430.1| 348|Homo sapiens TUWD12 protein. 81 4e-15
AB053266-1|BAB69057.1| 348|Homo sapiens TUWD12 protein. 81 4e-15
AL354928-6|CAI39637.1| 314|Homo sapiens WD repeat domain 38 pro... 80 9e-15
AL121990-7|CAI22015.1| 589|Homo sapiens TAF5-like RNA polymeras... 78 4e-14
AJ009770-1|CAA08816.1| 260|Homo sapiens putative transcription ... 78 4e-14
AF069736-1|AAC39906.1| 589|Homo sapiens PCAF associated factor ... 78 4e-14
M36429-1|AAA63264.1| 340|Homo sapiens protein ( Human transduci... 74 4e-13
M16514-1|AAA03179.1| 340|Homo sapiens GNB2 protein. 74 4e-13
CR541729-1|CAG46530.1| 340|Homo sapiens GNB2 protein. 74 4e-13
BC068003-1|AAH68003.1| 340|Homo sapiens guanine nucleotide bind... 74 4e-13
BC012348-1|AAH12348.1| 340|Homo sapiens guanine nucleotide bind... 74 4e-13
BC010073-1|AAH10073.1| 340|Homo sapiens guanine nucleotide bind... 74 4e-13
AF501883-1|AAM15919.1| 340|Homo sapiens guanine nucleotide bind... 74 4e-13
AF053356-4|AAC78794.1| 340|Homo sapiens GNB2 protein. 74 4e-13
X95525-1|CAA64777.1| 799|Homo sapiens hTAFII100 protein. 73 8e-13
U80191-1|AAC51215.1| 800|Homo sapiens TFIID subunit TAFII100 pr... 73 8e-13
U75309-1|AAC50902.1| 801|Homo sapiens TBP-associated factor pro... 73 8e-13
BC052268-1|AAH52268.2| 800|Homo sapiens TAF5 RNA polymerase II,... 73 8e-13
AL591408-4|CAI16747.1| 800|Homo sapiens TAF5 RNA polymerase II,... 73 8e-13
AK223615-1|BAD97335.1| 803|Homo sapiens Transcription initiatio... 73 8e-13
X04526-2|CAA28207.1| 340|Homo sapiens protein ( Human liver mRN... 73 1e-12
M36430-1|AAA63265.1| 247|Homo sapiens protein ( Human transduci... 73 1e-12
CR456784-1|CAG33065.1| 340|Homo sapiens GNB1 protein. 73 1e-12
BT007305-1|AAP35969.1| 340|Homo sapiens guanine nucleotide bind... 73 1e-12
BC114618-1|AAI14619.1| 332|Homo sapiens GNB1 protein protein. 73 1e-12
BC008991-1|AAH08991.1| 340|Homo sapiens guanine nucleotide bind... 73 1e-12
BC005888-1|AAH05888.1| 340|Homo sapiens guanine nucleotide bind... 73 1e-12
BC004186-1|AAH04186.1| 340|Homo sapiens guanine nucleotide bind... 73 1e-12
AL109917-5|CAI95654.1| 340|Homo sapiens guanine nucleotide bind... 73 1e-12
AL031282-2|CAI20029.1| 340|Homo sapiens guanine nucleotide bind... 73 1e-12
AF501882-1|AAM15918.1| 340|Homo sapiens guanine nucleotide bind... 73 1e-12
AF070603-1|AAC28655.1| 207|Homo sapiens beta-subunit signal tra... 73 1e-12
M16538-1|AAA35922.1| 340|Homo sapiens protein ( Human signal-tr... 72 2e-12
CR456762-1|CAG33043.1| 655|Homo sapiens KATNB1 protein. 72 2e-12
BT007022-1|AAP35668.1| 655|Homo sapiens katanin p80 (WD40-conta... 72 2e-12
BC001353-1|AAH01353.1| 655|Homo sapiens katanin p80 (WD repeat ... 72 2e-12
AF001687-1|AAB87640.1| 521|Homo sapiens U4/U6 snRNP 60 kDa prot... 72 2e-12
AF052432-1|AAC09328.1| 655|Homo sapiens katanin p80 subunit pro... 71 3e-12
BC036377-1|AAH36377.1| 415|Homo sapiens WD repeat domain 69 pro... 71 6e-12
AK097409-1|BAC05039.1| 415|Homo sapiens protein ( Homo sapiens ... 71 6e-12
AC073065-2|AAX93215.1| 415|Homo sapiens unknown protein. 71 6e-12
U82756-1|AAC02261.1| 520|Homo sapiens WD splicing factor Hprp4p... 70 1e-11
CR457105-1|CAG33386.1| 521|Homo sapiens PRPF4 protein. 70 1e-11
BC007424-1|AAH07424.1| 521|Homo sapiens PRP4 pre-mRNA processin... 70 1e-11
BC001588-1|AAH01588.1| 522|Homo sapiens PRP4 pre-mRNA processin... 70 1e-11
AY572489-1|AAS78572.1| 521|Homo sapiens 60 kDa U4/U6 snRNP-spec... 70 1e-11
AL449305-8|CAI10969.1| 521|Homo sapiens PRP4 pre-mRNA processin... 70 1e-11
AL449305-7|CAI10968.1| 522|Homo sapiens PRP4 pre-mRNA processin... 70 1e-11
AF016369-1|AAC51925.1| 522|Homo sapiens U4/U6 small nuclear rib... 70 1e-11
AB209797-1|BAD93034.1| 537|Homo sapiens PRPF4 protein variant p... 70 1e-11
BC012075-1|AAH12075.1| 485|Homo sapiens notchless homolog 1 (Dr... 69 1e-11
BC002884-1|AAH02884.2| 484|Homo sapiens NLE1 protein protein. 69 1e-11
AK001320-1|BAA91621.1| 485|Homo sapiens protein ( Homo sapiens ... 69 1e-11
AB209111-1|BAD92348.1| 487|Homo sapiens Notchless gene homolog ... 69 1e-11
AK127882-1|BAC87175.1| 369|Homo sapiens protein ( Homo sapiens ... 69 2e-11
AK098821-1|BAC05425.1| 415|Homo sapiens protein ( Homo sapiens ... 69 2e-11
BC000873-1|AAH00873.1| 340|Homo sapiens guanine nucleotide bind... 69 2e-11
AF300648-1|AAG18442.1| 340|Homo sapiens guanine nucleotide bind... 69 2e-11
BC106004-1|AAI06005.1| 514|Homo sapiens pleiotropic regulator 1... 68 3e-11
BC020786-1|AAH20786.1| 505|Homo sapiens PLRG1 protein protein. 68 3e-11
AF044333-1|AAD09407.1| 514|Homo sapiens pleiotropic regulator 1... 68 3e-11
BC031227-1|AAH31227.2| 452|Homo sapiens WDR88 protein protein. 68 4e-11
BC015887-1|AAH15887.1| 404|Homo sapiens WD repeat and SOCS box-... 68 4e-11
AF229181-1|AAF71302.1| 404|Homo sapiens CS box-containing WD pr... 68 4e-11
AF163324-1|AAF80478.1| 404|Homo sapiens WSB-2 protein. 68 4e-11
AL031282-15|CAI20051.1| 197|Homo sapiens guanine nucleotide bin... 67 5e-11
EF011621-1|ABK41111.1| 357|Homo sapiens CDW11/WDR57 protein. 66 1e-10
BC021110-1|AAH21110.1| 421|Homo sapiens WD repeat and SOCS box-... 66 1e-10
BC015920-1|AAH15920.1| 297|Homo sapiens GNB3 protein protein. 66 1e-10
BC001494-1|AAH01494.1| 357|Homo sapiens WD repeat domain 57 (U5... 66 1e-10
AL451070-1|CAH71848.1| 357|Homo sapiens WD repeat domain 57 (U5... 66 1e-10
AK074917-1|BAC11291.1| 421|Homo sapiens protein ( Homo sapiens ... 66 1e-10
AF240696-1|AAF82746.1| 275|Homo sapiens WSB1 isoform 2 protein. 66 1e-10
AF208838-1|AAL34973.1| 410|Homo sapiens Miller-Dieker lissencep... 66 1e-10
AF112205-1|AAF17193.1| 421|Homo sapiens WSB-1 protein protein. 66 1e-10
AF072880-1|AAD28808.1| 421|Homo sapiens SOCS box-containing WD ... 66 1e-10
AF069313-1|AAD20954.2| 421|Homo sapiens WSB1 protein protein. 66 1e-10
AF090988-1|AAC69625.1| 357|Homo sapiens U5 snRNP-specific 40 kD... 66 2e-10
AF083383-1|AAC64084.1| 310|Homo sapiens 38kDa splicing factor p... 66 2e-10
U72342-1|AAC51111.1| 410|Homo sapiens platelet activating facto... 65 2e-10
L13387-1|AAA02882.1| 288|Homo sapiens Miller-Dieker lissencepha... 65 2e-10
L13386-1|AAA02881.1| 410|Homo sapiens Miller-Dieker lissencepha... 65 2e-10
L13385-1|AAA02880.1| 410|Homo sapiens Miller-Dieker lissencepha... 65 2e-10
BC064638-1|AAH64638.1| 410|Homo sapiens platelet-activating fac... 65 2e-10
BC035409-1|AAH35409.1| 808|Homo sapiens transducin (beta)-like ... 65 2e-10
BC014007-1|AAH14007.1| 808|Homo sapiens TBL3 protein protein. 65 2e-10
BC010231-1|AAH10231.1| 808|Homo sapiens transducin (beta)-like ... 65 2e-10
BC007620-1|AAH07620.1| 570|Homo sapiens TBL3 protein protein. 65 2e-10
AF400434-1|AAK92483.1| 410|Homo sapiens platelet-activating fac... 65 2e-10
AF208837-1|AAL34972.1| 410|Homo sapiens Miller-Dieker lissencep... 65 2e-10
AB209173-1|BAD92410.1| 832|Homo sapiens transducin beta-like 3 ... 65 2e-10
AK131444-1|BAD18589.1| 472|Homo sapiens protein ( Homo sapiens ... 64 5e-10
AF106683-1|AAD43036.1| 421|Homo sapiens WSB-1 protein. 64 5e-10
BC026353-1|AAH26353.1| 677|Homo sapiens WD repeat domain 48 pro... 63 8e-10
AF468833-1|AAL78650.1| 677|Homo sapiens WD repeat endosomal pro... 63 8e-10
AB040882-1|BAA95973.2| 680|Homo sapiens KIAA1449 protein protein. 63 8e-10
AK222576-1|BAD96296.1| 421|Homo sapiens WD SOCS-box protein 1 i... 63 1e-09
BC026213-1|AAH26213.1| 529|Homo sapiens F-box and WD repeat dom... 62 2e-09
AF176022-1|AAF04528.1| 542|Homo sapiens F-box protein Fbw1b pro... 62 2e-09
AB033281-1|BAA92331.1| 542|Homo sapiens F-box and WD-repeats pr... 62 2e-09
AB033280-1|BAA92330.1| 529|Homo sapiens F-box and WD-repeats pr... 62 2e-09
AB033279-1|BAA92329.1| 508|Homo sapiens F-box and WD-repeats pr... 62 2e-09
AB014596-1|BAA31671.1| 550|Homo sapiens KIAA0696 protein protein. 62 2e-09
Y14153-1|CAA74572.1| 569|Homo sapiens beta-transducin repeats c... 62 3e-09
BC027994-1|AAH27994.1| 605|Homo sapiens beta-transducin repeat ... 62 3e-09
AL627424-18|CAI41043.1| 569|Homo sapiens beta-transducin repeat... 62 3e-09
AL627424-17|CAI41042.1| 605|Homo sapiens beta-transducin repeat... 62 3e-09
AL445463-3|CAI12964.1| 569|Homo sapiens beta-transducin repeat ... 62 3e-09
AL445463-2|CAI12963.1| 605|Homo sapiens beta-transducin repeat ... 62 3e-09
AL133387-2|CAH70019.1| 569|Homo sapiens beta-transducin repeat ... 62 3e-09
AL133387-1|CAH70020.1| 605|Homo sapiens beta-transducin repeat ... 62 3e-09
AF129530-1|AAF04464.1| 569|Homo sapiens F-box protein Fbw1A pro... 62 3e-09
AF101784-1|AAD08702.1| 605|Homo sapiens b-TRCP variant E3RS-Ika... 62 3e-09
BC025379-1|AAH25379.1| 571|Homo sapiens SPAG16 protein protein. 61 3e-09
AF490390-1|AAM97147.1| 631|Homo sapiens sperm-associated WD rep... 61 3e-09
AF310672-1|AAM63956.1| 631|Homo sapiens PF20 variant 1a protein. 61 3e-09
EF560718-1|ABQ59028.1| 1205|Homo sapiens APAF1 protein protein. 60 6e-09
BC037320-1|AAH37320.1| 621|Homo sapiens FBXW7 protein protein. 60 6e-09
AJ243007-1|CAB55583.1| 1205|Homo sapiens apoptotic protease acti... 60 6e-09
AJ243006-1|CAB55582.1| 1205|Homo sapiens apoptotic protease acti... 60 6e-09
AJ243004-1|CAB55580.1| 1205|Homo sapiens apoptotic protease acti... 60 6e-09
AJ243003-1|CAB55579.1| 1205|Homo sapiens apoptotic protease acti... 60 6e-09
AF013263-1|AAC51678.1| 1194|Homo sapiens apoptotic protease acti... 60 6e-09
AJ243011-1|CAB55587.1| 1205|Homo sapiens protease activating fac... 60 1e-08
AJ243010-1|CAB55586.1| 1205|Homo sapiens apoptotic protease acti... 60 1e-08
AJ243005-1|CAB55581.1| 1205|Homo sapiens apoptotic protease acti... 60 1e-08
BC117246-1|AAI17247.1| 707|Homo sapiens F-box and WD repeat dom... 59 2e-08
BC117244-1|AAI17245.1| 707|Homo sapiens F-box and WD repeat dom... 59 2e-08
AY049984-1|AAL07271.1| 707|Homo sapiens F-box protein CDC4 prot... 59 2e-08
AY033553-1|AAK57547.1| 627|Homo sapiens F-box protein FBW7 prot... 59 2e-08
AY008274-1|AAG16640.1| 589|Homo sapiens F-box protein SEL10 pro... 59 2e-08
AK223449-1|BAD97169.1| 627|Homo sapiens F-box protein FBW7 isof... 59 2e-08
AK001933-1|BAA91986.1| 553|Homo sapiens protein ( Homo sapiens ... 59 2e-08
AF411972-1|AAL06291.1| 627|Homo sapiens archipelago beta form p... 59 2e-08
AF411971-1|AAL06290.1| 707|Homo sapiens archipelago alpha form ... 59 2e-08
AF383178-1|AAK60269.1| 561|Homo sapiens F-box protein FBX30 pro... 59 2e-08
AB209725-1|BAD92962.1| 624|Homo sapiens F-box protein FBW7 isof... 59 2e-08
M99435-1|AAA61192.1| 770|Homo sapiens transducin-like enhancer ... 58 2e-08
BC015747-1|AAH15747.1| 770|Homo sapiens transducin-like enhance... 58 2e-08
BC013997-1|AAH13997.1| 353|Homo sapiens guanine nucleotide bind... 58 2e-08
BC010100-1|AAH10100.1| 770|Homo sapiens transducin-like enhance... 58 2e-08
AL365190-2|CAI14977.1| 770|Homo sapiens transducin-like enhance... 58 2e-08
AL353682-1|CAI12595.1| 770|Homo sapiens transducin-like enhance... 58 2e-08
AL121993-4|CAI22739.1| 943|Homo sapiens WD repeat domain 3 prot... 58 2e-08
AF501885-1|AAM15921.1| 353|Homo sapiens guanine nucleotide bind... 58 2e-08
AF300650-1|AAG18444.1| 395|Homo sapiens guanine nucleotide bind... 58 2e-08
AF083217-1|AAD45865.1| 943|Homo sapiens WD repeat protein WDR3 ... 58 2e-08
AF017656-1|AAC63826.1| 353|Homo sapiens G protein beta 5 subuni... 58 2e-08
AB209201-1|BAD92438.1| 466|Homo sapiens WD repeat-containing pr... 58 2e-08
M99439-1|AAA61195.1| 448|Homo sapiens transducin-like enhancer ... 58 3e-08
M99436-1|AAA61193.1| 743|Homo sapiens transducin-like enhancer ... 58 3e-08
BC059405-1|AAH59405.2| 805|Homo sapiens TLE4 protein protein. 58 3e-08
BC045650-1|AAH45650.1| 704|Homo sapiens TLE4 protein protein. 58 3e-08
AL445252-3|CAI13644.1| 764|Homo sapiens transducin-like enhance... 58 3e-08
AL358975-3|CAI13734.1| 764|Homo sapiens transducin-like enhance... 58 3e-08
AL353813-5|CAI41315.1| 764|Homo sapiens transducin-like enhance... 58 3e-08
AJ243107-1|CAB56462.1| 1171|Homo sapiens apoptotic protease acti... 58 3e-08
AB033087-1|BAA86575.1| 787|Homo sapiens KIAA1261 protein protein. 58 3e-08
M99438-1|AAA61194.1| 772|Homo sapiens transducin-like enhancer ... 58 4e-08
AY583459-1|AAS90945.1| 764|Homo sapiens transducin-like enhance... 58 4e-08
EF079890-1|ABN48555.1| 444|Homo sapiens ATG16 autophagy related... 57 6e-08
EF079889-1|ABN48554.1| 588|Homo sapiens ATG16 autophagy related... 57 6e-08
BC117337-1|AAI17338.1| 523|Homo sapiens ATG16L1 protein protein. 57 6e-08
BC071846-1|AAH71846.1| 475|Homo sapiens ATG16L1 protein protein. 57 6e-08
BC043247-1|AAH43247.1| 767|Homo sapiens TLE3 protein protein. 57 6e-08
BC041831-1|AAH41831.1| 772|Homo sapiens TLE3 protein protein. 57 6e-08
AY583460-1|AAS90946.1| 767|Homo sapiens transducin-like enhance... 57 6e-08
AY398617-1|AAR32130.1| 607|Homo sapiens APG16L beta protein. 57 6e-08
AK027854-1|BAB55412.1| 504|Homo sapiens protein ( Homo sapiens ... 57 6e-08
AJ243008-1|CAB55584.1| 1205|Homo sapiens apoptotic protease acti... 57 6e-08
AC013726-3|AAY14860.1| 523|Homo sapiens unknown protein. 57 6e-08
AB046767-1|BAB13373.1| 863|Homo sapiens KIAA1547 protein protein. 57 6e-08
EF560734-1|ABQ59044.1| 588|Homo sapiens ATG16L1 protein protein. 57 7e-08
BX679664-5|CAH71325.1| 891|Homo sapiens WD repeat domain 47 pro... 56 1e-07
BX679664-4|CAH71327.1| 919|Homo sapiens WD repeat domain 47 pro... 56 1e-07
BX679664-3|CAH71326.1| 920|Homo sapiens WD repeat domain 47 pro... 56 1e-07
BC039254-1|AAH39254.1| 893|Homo sapiens WDR47 protein protein. 56 1e-07
BC017364-1|AAH17364.1| 743|Homo sapiens transducin-like enhance... 56 1e-07
AY358182-1|AAQ88549.1| 470|Homo sapiens SSGL9393 protein. 56 1e-07
AL449266-4|CAI14352.1| 891|Homo sapiens WD repeat domain 47 pro... 56 1e-07
AL449266-3|CAI14353.1| 919|Homo sapiens WD repeat domain 47 pro... 56 1e-07
AL449266-2|CAI14351.1| 920|Homo sapiens WD repeat domain 47 pro... 56 1e-07
AC007766-2|AAD38075.1| 553|Homo sapiens TLE2_HUMAN [AA 191- 743... 56 1e-07
AB020700-1|BAA74916.2| 974|Homo sapiens KIAA0893 protein protein. 56 1e-07
BC150255-1|AAI50256.1| 1237|Homo sapiens apoptotic peptidase act... 56 1e-07
BC036713-1|AAH36713.1| 542|Homo sapiens ATG16L2 protein protein. 56 1e-07
AK093017-1|BAC04021.1| 619|Homo sapiens protein ( Homo sapiens ... 56 1e-07
AJ243048-1|CAB55588.1| 1248|Homo sapiens apoptotic protease acti... 56 1e-07
AJ243009-1|CAB55585.1| 1248|Homo sapiens apoptotic protease acti... 56 1e-07
AF149794-1|AAD34016.1| 1248|Homo sapiens apoptotic protease acti... 56 1e-07
AF134397-1|AAD38344.1| 1237|Homo sapiens apoptotic protease acti... 56 1e-07
AB007873-1|BAA24843.2| 1237|Homo sapiens KIAA0413 protein. 56 1e-07
BC034964-1|AAH34964.1| 920|Homo sapiens WD repeat domain 47 pro... 55 2e-07
AK074434-1|BAB85082.1| 293|Homo sapiens protein ( Homo sapiens ... 55 2e-07
BC012352-1|AAH12352.1| 366|Homo sapiens WDR31 protein protein. 55 3e-07
AL449305-1|CAI10961.1| 367|Homo sapiens WD repeat domain 31 pro... 55 3e-07
AL137066-1|CAH70096.1| 367|Homo sapiens WD repeat domain 31 pro... 55 3e-07
AK093240-1|BAC04106.1| 367|Homo sapiens protein ( Homo sapiens ... 55 3e-07
BC113421-1|AAI13422.1| 514|Homo sapiens transducin (beta)-like ... 54 5e-07
AK022956-1|BAB14331.1| 514|Homo sapiens protein ( Homo sapiens ... 54 5e-07
AF314544-1|AAK00301.1| 514|Homo sapiens nuclear receptor co-rep... 54 5e-07
AF268193-1|AAG44736.1| 514|Homo sapiens IRA1 protein. 54 5e-07
AC006011-2|AAX82033.1| 1336|Homo sapiens unknown protein. 54 5e-07
AB044749-1|BAB32435.1| 1336|Homo sapiens WDC146 protein. 54 5e-07
Y12781-1|CAA73319.1| 577|Homo sapiens transducin (beta) like 1 ... 54 7e-07
X95263-1|CAA64560.1| 919|Homo sapiens PWP2 protein. 54 7e-07
U56089-1|AAC50905.1| 919|Homo sapiens periodic tryptophan prote... 54 7e-07
U56085-1|AAC50904.1| 919|Homo sapiens periodic tryptophan prote... 54 7e-07
U53346-1|AAB08084.1| 919|Homo sapiens PWP2H protein protein. 54 7e-07
D26488-1|BAA05499.1| 686|Homo sapiens KIAA0007 protein. 54 7e-07
BC052304-1|AAH52304.1| 577|Homo sapiens transducin (beta)-like ... 54 7e-07
BC032708-1|AAH32708.1| 526|Homo sapiens TBL1X protein protein. 54 7e-07
BC014988-1|AAH14988.1| 919|Homo sapiens PWP2 periodic tryptopha... 54 7e-07
BC013309-1|AAH13309.1| 919|Homo sapiens PWP2 periodic tryptopha... 54 7e-07
AP001753-1|BAA95553.1| 919|Homo sapiens periodic tryptophan pro... 54 7e-07
AK093494-1|BAC04184.1| 476|Homo sapiens protein ( Homo sapiens ... 54 7e-07
AB209608-1|BAD92845.1| 540|Homo sapiens transducin beta-like 1X... 54 7e-07
AB209438-1|BAD92675.1| 316|Homo sapiens PWP2 periodic tryptopha... 54 7e-07
AB001517-2|BAA21137.1| 919|Homo sapiens PWP2 protein protein. 54 7e-07
BC023662-1|AAH23662.2| 475|Homo sapiens RRP9, small subunit (SS... 53 9e-07
BC010048-1|AAH10048.1| 475|Homo sapiens RRP9, small subunit (SS... 53 9e-07
BC009879-1|AAH09879.1| 475|Homo sapiens RRP9, small subunit (SS... 53 9e-07
BC001113-1|AAH01113.1| 475|Homo sapiens RRP9, small subunit (SS... 53 9e-07
AK090597-1|BAC03485.1| 513|Homo sapiens protein ( Homo sapiens ... 53 9e-07
AK074217-1|BAB85020.1| 506|Homo sapiens protein ( Homo sapiens ... 53 9e-07
AJ001340-1|CAA04687.1| 475|Homo sapiens U3 snoRNP associated 55... 53 9e-07
X74262-1|CAA52321.1| 425|Homo sapiens retinoblastoma binding pr... 52 2e-06
X71810-1|CAA50685.1| 410|Homo sapiens IEF SSP 9306 protein. 52 2e-06
X70476-1|CAA49900.1| 906|Homo sapiens subunit of coatomer compl... 52 2e-06
BT007309-1|AAP35973.1| 425|Homo sapiens retinoblastoma binding ... 52 2e-06
BC130473-1|AAI30474.1| 522|Homo sapiens transducin (beta)-like ... 52 2e-06
BC130471-1|AAI30472.1| 522|Homo sapiens transducin (beta)-like ... 52 2e-06
BC075836-1|AAH75836.1| 425|Homo sapiens retinoblastoma binding ... 52 2e-06
BC053904-1|AAH53904.1| 425|Homo sapiens retinoblastoma binding ... 52 2e-06
BC015123-1|AAH15123.1| 365|Homo sapiens Similar to retinoblasto... 52 2e-06
BC003092-1|AAH03092.1| 425|Homo sapiens retinoblastoma binding ... 52 2e-06
BC000326-1|AAH00326.1| 906|Homo sapiens coatomer protein comple... 52 2e-06
AK222779-1|BAD96499.1| 424|Homo sapiens retinoblastoma binding ... 52 2e-06
AF332222-1|AAK13474.1| 522|Homo sapiens transducin beta-like 1 ... 52 2e-06
AF332221-1|AAK13473.1| 522|Homo sapiens transducin beta-like 1 ... 52 2e-06
AF332220-1|AAK13472.1| 522|Homo sapiens transducin beta-like 1 ... 52 2e-06
U24105-1|AAB70879.1| 1224|Homo sapiens coatomer protein protein. 52 3e-06
BC111490-1|AAI11491.1| 768|Homo sapiens BRWD3 protein protein. 52 3e-06
BC041124-1|AAH41124.1| 917|Homo sapiens neutral sphingomyelinas... 52 3e-06
BC038447-1|AAH38447.1| 1233|Homo sapiens COPA protein protein. 52 3e-06
AY497047-1|AAS45472.1| 1631|Homo sapiens bromodomain and WD repe... 52 3e-06
AY497046-1|AAS45471.1| 1802|Homo sapiens bromodomain and WD repe... 52 3e-06
AL669934-1|CAI95405.1| 1802|Homo sapiens bromodomain and WD repe... 52 3e-06
AL590031-1|CAI39936.2| 1802|Homo sapiens bromodomain and WD repe... 52 3e-06
AL513282-3|CAI12455.1| 1233|Homo sapiens coatomer protein comple... 52 3e-06
AL513282-2|CAI12454.1| 1224|Homo sapiens coatomer protein comple... 52 3e-06
AL512504-2|CAI95143.1| 1802|Homo sapiens bromodomain and WD repe... 52 3e-06
AL445230-2|CAI15004.1| 1233|Homo sapiens coatomer protein comple... 52 3e-06
AL445230-1|CAI15005.1| 1224|Homo sapiens coatomer protein comple... 52 3e-06
AL163279-2|CAB90452.1| 2295|Homo sapiens homolog to cAMP respons... 52 3e-06
AJ292466-1|CAC44372.1| 2269|Homo sapiens WDR9 protein, form B p... 52 3e-06
AJ292465-1|CAC44371.1| 2320|Homo sapiens WDR9 protein, form A pr... 52 3e-06
AJ238214-1|CAC37033.2| 2269|Homo sapiens hypothetical protein pr... 52 3e-06
AB080587-1|BAD74072.1| 2199|Homo sapiens WD repeat protein WDR9-... 52 3e-06
AB080586-1|BAD74071.1| 2269|Homo sapiens WD repeat protein protein. 52 3e-06
U63810-1|AAC24948.1| 339|Homo sapiens WD40 protein Ciao 1 protein. 51 4e-06
EF011618-1|ABK41108.1| 339|Homo sapiens CDW8/WDR39 protein. 51 4e-06
EF011617-1|ABK41107.1| 423|Homo sapiens CDW7/WDR12 protein. 51 4e-06
EF011613-1|ABK41103.1| 513|Homo sapiens CDW3/SMU1 protein. 51 4e-06
CR457333-1|CAG33614.1| 305|Homo sapiens REC14 protein. 51 4e-06
CR456802-1|CAG33083.1| 339|Homo sapiens CIAO1 protein. 51 4e-06
BC110654-1|AAI10655.1| 513|Homo sapiens smu-1 suppressor of mec... 51 4e-06
BC032812-1|AAH32812.1| 339|Homo sapiens cytosolic iron-sulfur p... 51 4e-06
BC010080-1|AAH10080.1| 305|Homo sapiens WD repeat domain 61 pro... 51 4e-06
BC008082-1|AAH08082.1| 423|Homo sapiens WD repeat domain 12 pro... 51 4e-06
BC002876-1|AAH02876.1| 513|Homo sapiens smu-1 suppressor of mec... 51 4e-06
BC001395-1|AAH01395.1| 339|Homo sapiens cytosolic iron-sulfur p... 51 4e-06
AL162590-6|CAI15554.1| 513|Homo sapiens smu-1 suppressor of mec... 51 4e-06
AK223257-1|BAD96977.1| 339|Homo sapiens WD40 protein Ciao1 vari... 51 4e-06
AK024754-1|BAB14986.1| 305|Homo sapiens protein ( Homo sapiens ... 51 4e-06
AK001743-1|BAA91875.1| 423|Homo sapiens protein ( Homo sapiens ... 51 4e-06
AK001667-1|BAA91822.1| 513|Homo sapiens protein ( Homo sapiens ... 51 4e-06
AF309553-1|AAG31639.1| 305|Homo sapiens meiotic recombination p... 51 4e-06
AF242546-1|AAF60355.1| 423|Homo sapiens YTM1 protein. 51 4e-06
AF100786-1|AAP97225.1| 305|Homo sapiens G protein beta subunit-... 51 4e-06
AC010900-2|AAY24287.1| 423|Homo sapiens unknown protein. 51 4e-06
AC004020-1|AAC23493.1| 339|Homo sapiens Unknown gene product pr... 51 4e-06
X96586-1|CAA65405.1| 917|Homo sapiens FAN protein protein. 51 5e-06
AY295082-1|AAQ63174.1| 544|Homo sapiens pre-mRNA splicing facto... 51 5e-06
AK131383-1|BAD18534.1| 141|Homo sapiens protein ( Homo sapiens ... 51 5e-06
AK022782-1|BAB14243.1| 423|Homo sapiens protein ( Homo sapiens ... 51 5e-06
AK022781-1|BAB14242.1| 423|Homo sapiens protein ( Homo sapiens ... 51 5e-06
X72841-1|CAA51360.1| 425|Homo sapiens IEF 7442 protein. 50 6e-06
U35143-1|AAC50231.1| 425|Homo sapiens retinoblastoma-binding pr... 50 6e-06
CR541701-1|CAG46502.1| 425|Homo sapiens RBBP7 protein. 50 6e-06
BC150246-1|AAI50247.1| 1563|Homo sapiens WDFY3 protein protein. 50 6e-06
BC114501-1|AAI14502.1| 425|Homo sapiens retinoblastoma binding ... 50 6e-06
BC114500-1|AAI14501.1| 425|Homo sapiens retinoblastoma binding ... 50 6e-06
BC065502-1|AAH65502.1| 778|Homo sapiens WDFY3 protein protein. 50 6e-06
BC032551-1|AAH32551.1| 795|Homo sapiens phospholipase A2-activa... 50 6e-06
BC015214-1|AAH15214.2| 437|Homo sapiens WDFY3 protein protein. 50 6e-06
AL929302-6|CAI41284.1| 420|Homo sapiens retinoblastoma binding ... 50 6e-06
AL929302-5|CAI41283.1| 469|Homo sapiens retinoblastoma binding ... 50 6e-06
AL929302-3|CAI41281.1| 175|Homo sapiens retinoblastoma binding ... 50 6e-06
AL356133-3|CAH72641.1| 738|Homo sapiens phospholipase A2-activa... 50 6e-06
AK223544-1|BAD97264.1| 748|Homo sapiens Hypothetical protein DK... 50 6e-06
AK055806-1|BAB71020.1| 722|Homo sapiens protein ( Homo sapiens ... 50 6e-06
AK002143-1|BAA92105.1| 544|Homo sapiens protein ( Homo sapiens ... 50 6e-06
AJ238243-1|CAB42881.1| 738|Homo sapiens phospholipase A2 activa... 50 6e-06
AF538685-1|AAN15137.1| 3526|Homo sapiens ALFY protein. 50 6e-06
AF145020-1|AAD42075.1| 649|Homo sapiens phospholipase A2 activa... 50 6e-06
AF083395-1|AAD03030.1| 738|Homo sapiens phospholipase A2-activa... 50 6e-06
AB023210-1|BAA76837.2| 1556|Homo sapiens KIAA0993 protein protein. 50 6e-06
BC018698-1|AAH18698.1| 504|Homo sapiens PRP19/PSO4 pre-mRNA pro... 50 8e-06
BC018665-1|AAH18665.1| 504|Homo sapiens PRP19/PSO4 pre-mRNA pro... 50 8e-06
BC008719-1|AAH08719.1| 504|Homo sapiens PRP19/PSO4 pre-mRNA pro... 50 8e-06
AJ131186-1|CAB51857.1| 504|Homo sapiens nuclear matrix protein ... 50 8e-06
CR456496-1|CAG30382.1| 327|Homo sapiens GNB1L protein. 50 1e-05
BC110334-1|AAI10335.1| 454|Homo sapiens F-box and WD repeat dom... 50 1e-05
BC018738-1|AAH18738.1| 454|Homo sapiens F-box and WD repeat dom... 50 1e-05
BC012060-1|AAH12060.1| 327|Homo sapiens guanine nucleotide bind... 50 1e-05
AL161911-3|CAI95114.1| 208|Homo sapiens F-box and WD repeat dom... 50 1e-05
AL161911-2|CAI95113.1| 454|Homo sapiens F-box and WD repeat dom... 50 1e-05
AK022484-1|BAB14051.1| 454|Homo sapiens protein ( Homo sapiens ... 50 1e-05
AF301895-1|AAG53933.1| 327|Homo sapiens WDVCF protein. 50 1e-05
AF238328-1|AAG36826.1| 212|Homo sapiens G protein beta-subunit-... 50 1e-05
AF176698-1|AAF13226.1| 422|Homo sapiens F-box protein FBW2 prot... 50 1e-05
AF145024-1|AAP97276.1| 422|Homo sapiens MD6 protein protein. 50 1e-05
AF129531-1|AAF04465.1| 422|Homo sapiens F-box protein Fbw2 prot... 50 1e-05
AB051432-1|BAB33315.1| 386|Homo sapiens KIAA1645 protein protein. 50 1e-05
AB049212-1|BAB68408.1| 327|Homo sapiens G-protein beta subunit ... 50 1e-05
AK123876-1|BAC85713.1| 428|Homo sapiens protein ( Homo sapiens ... 49 1e-05
AF492460-1|AAN64030.1| 1322|Homo sapiens WD repeat 17 protein. 49 2e-05
BC126114-1|AAI26115.1| 579|Homo sapiens cell division cycle 40 ... 48 3e-05
BC117145-1|AAI17146.1| 579|Homo sapiens cell division cycle 40 ... 48 3e-05
AL671518-2|CAI13322.1| 579|Homo sapiens cell division cycle 40 ... 48 3e-05
AL671518-1|CAI13321.1| 539|Homo sapiens cell division cycle 40 ... 48 3e-05
AL445068-1|CAI22519.1| 539|Homo sapiens cell division cycle 40 ... 48 3e-05
AK222721-1|BAD96441.1| 579|Homo sapiens pre-mRNA splicing facto... 48 3e-05
AF061241-1|AAC25166.1| 542|Homo sapiens splicing factor hPRP17 ... 48 3e-05
AF038392-1|AAC39730.1| 579|Homo sapiens pre-mRNA splicing facto... 48 3e-05
AB208903-1|BAD92140.1| 501|Homo sapiens pre-mRNA splicing facto... 48 3e-05
U88871-1|AAC51238.1| 323|Homo sapiens HsPex7p protein. 48 3e-05
U76560-1|AAB50556.1| 323|Homo sapiens peroxisome targeting sign... 48 3e-05
CR542076-1|CAG46873.1| 323|Homo sapiens PEX7 protein. 48 3e-05
CR542054-1|CAG46851.1| 323|Homo sapiens PEX7 protein. 48 3e-05
BC031606-1|AAH31606.1| 280|Homo sapiens PEX7 protein protein. 48 3e-05
BC006268-1|AAH06268.1| 323|Homo sapiens peroxisomal biogenesis ... 48 3e-05
AL365223-4|CAI15714.1| 323|Homo sapiens peroxisomal biogenesis ... 48 3e-05
AL121933-2|CAI15471.1| 323|Homo sapiens peroxisomal biogenesis ... 48 3e-05
AF180814-1|AAF37350.1| 323|Homo sapiens peroxisomal PTS2 recept... 48 3e-05
BT020045-1|AAV38848.1| 350|Homo sapiens unr-interacting protein... 48 4e-05
BT020044-1|AAV38847.1| 350|Homo sapiens unr-interacting protein... 48 4e-05
BC062306-1|AAH62306.1| 350|Homo sapiens serine/threonine kinase... 48 4e-05
BC026335-1|AAH26335.1| 475|Homo sapiens coronin, actin binding ... 48 4e-05
BC024267-1|AAH24267.1| 594|Homo sapiens TRAF7 protein protein. 48 4e-05
BC000162-1|AAH00162.1| 350|Homo sapiens serine/threonine kinase... 48 4e-05
AY569455-1|AAS68363.1| 670|Homo sapiens TRAF7 protein. 48 4e-05
AY049776-1|AAL15433.1| 350|Homo sapiens unr-interacting protein... 48 4e-05
AK001642-1|BAA91803.1| 795|Homo sapiens protein ( Homo sapiens ... 48 4e-05
AJ010025-1|CAB38041.1| 350|Homo sapiens unr-interacting protein... 48 4e-05
AB024327-1|BAA75544.1| 350|Homo sapiens WD-40 repeat protein pr... 48 4e-05
AB023142-1|BAA76769.1| 479|Homo sapiens KIAA0925 protein protein. 48 4e-05
AB010098-1|BAA36341.1| 475|Homo sapiens ClipinC protein. 48 4e-05
U28413-1|AAA82605.1| 396|Homo sapiens CSA protein protein. 47 6e-05
CR536563-1|CAG38800.1| 396|Homo sapiens CKN1 protein. 47 6e-05
BT020021-1|AAV38824.1| 396|Homo sapiens Cockayne syndrome 1 (cl... 47 6e-05
AY213194-1|AAO21128.1| 396|Homo sapiens Cockayne syndrome 1 (cl... 47 6e-05
AL607085-2|CAI15166.1| 494|Homo sapiens WD repeat domain 37 pro... 47 6e-05
AJ005257-1|CAA06444.1| 86|Homo sapiens protein ( Homo sapiens ... 47 6e-05
AB023199-1|BAA76826.2| 502|Homo sapiens KIAA0982 protein protein. 47 6e-05
DQ924532-1|ABK76299.1| 1821|Homo sapiens pleckstrin homology dom... 47 8e-05
BC041032-1|AAH41032.1| 417|Homo sapiens prolactin regulatory el... 47 8e-05
BC021905-1|AAH21905.1| 896|Homo sapiens Unknown (protein for IM... 47 8e-05
BC016906-1|AAH16906.1| 345|Homo sapiens PREB protein protein. 47 8e-05
BC016472-1|AAH16472.1| 417|Homo sapiens prolactin regulatory el... 47 8e-05
BC012890-1|AAH12890.1| 417|Homo sapiens prolactin regulatory el... 47 8e-05
BC005870-1|AAH05870.1| 315|Homo sapiens mitogen-activated prote... 47 8e-05
BC002765-1|AAH02765.1| 417|Homo sapiens prolactin regulatory el... 47 8e-05
AL450327-2|CAH70884.1| 1821|Homo sapiens protein ( vel protein (... 47 8e-05
AL356776-2|CAI14406.1| 1821|Homo sapiens protein ( Human DNA seq... 47 8e-05
AK223195-1|BAD96915.1| 315|Homo sapiens mitogen-activated prote... 47 8e-05
AK057039-1|BAB71353.1| 912|Homo sapiens protein ( Homo sapiens ... 47 8e-05
AK023064-1|BAB14385.1| 417|Homo sapiens NA, nuclear gene encodi... 47 8e-05
AJ303102-1|CAC83118.1| 1821|Homo sapiens WD repeat domain 11 pro... 47 8e-05
AF227166-1|AAF74572.1| 417|Homo sapiens prolactin regulatory bi... 47 8e-05
AF226684-1|AAG01692.1| 417|Homo sapiens prolactin regulatory el... 47 8e-05
AF203687-1|AAF19192.1| 417|Homo sapiens SEC12 protein. 47 8e-05
AC013403-6|AAX93170.1| 417|Homo sapiens unknown protein. 47 8e-05
BT007115-1|AAP35779.1| 493|Homo sapiens Fzr1 protein protein. 46 1e-04
BC047574-1|AAH47574.1| 899|Homo sapiens WDFY4 protein protein. 46 1e-04
BC032420-1|AAH32420.1| 322|Homo sapiens WDFY4 protein protein. 46 1e-04
BC015694-1|AAH15694.2| 320|Homo sapiens WDFY4 protein protein. 46 1e-04
BC013413-1|AAH13413.1| 493|Homo sapiens fizzy/cell division cyc... 46 1e-04
AK074085-1|BAB84911.1| 1887|Homo sapiens FLJ00156 protein protein. 46 1e-04
AF433157-1|AAL28117.1| 404|Homo sapiens CDC20-like 1b protein. 46 1e-04
AF083810-1|AAD52030.1| 493|Homo sapiens fizzy-related protein p... 46 1e-04
AC005787-1|AAC62835.1| 493|Homo sapiens R33374_1 protein. 46 1e-04
AB046827-1|BAB13433.1| 1270|Homo sapiens KIAA1607 protein protein. 46 1e-04
AB033068-1|BAA86556.1| 504|Homo sapiens KIAA1242 protein protein. 46 1e-04
BC028364-1|AAH28364.1| 1061|Homo sapiens FBXW10 protein protein. 46 1e-04
AY729024-1|AAU43731.1| 1052|Homo sapiens ubiquitin ligase specif... 46 1e-04
AK074891-1|BAC11271.1| 242|Homo sapiens protein ( Homo sapiens ... 46 1e-04
AK022227-1|BAB13990.1| 217|Homo sapiens protein ( Homo sapiens ... 46 1e-04
AB209899-1|BAD93136.1| 967|Homo sapiens Hypothetical protein DK... 46 1e-04
AB075822-1|BAB85528.1| 445|Homo sapiens KIAA1942 protein protein. 46 1e-04
AB013463-1|BAA86955.1| 404|Homo sapiens Fzr2 protein. 46 1e-04
AB013462-1|BAA86954.1| 496|Homo sapiens Fzr1 protein. 46 1e-04
BC025392-1|AAH25392.1| 620|Homo sapiens WD repeat domain 16 pro... 46 2e-04
AK094847-1|BAC04435.1| 630|Homo sapiens protein ( Homo sapiens ... 46 2e-04
AK074435-1|BAB85083.1| 412|Homo sapiens protein ( Homo sapiens ... 46 2e-04
AJ223814-1|CAA11560.1| 780|Homo sapiens striatin protein. 46 2e-04
AB065281-1|BAB83743.1| 620|Homo sapiens WDR16 protein. 46 2e-04
EF011614-1|ABK41104.1| 446|Homo sapiens CDW4/GRWD1 protein. 45 2e-04
BC002440-1|AAH02440.1| 446|Homo sapiens glutamate-rich WD repea... 45 2e-04
AK123625-1|BAC85666.1| 129|Homo sapiens protein ( Homo sapiens ... 45 2e-04
AK074676-1|BAC11130.1| 446|Homo sapiens protein ( Homo sapiens ... 45 2e-04
AF411979-1|AAL04163.1| 420|Homo sapiens WD40- and FYVE-domain c... 45 2e-04
AF337808-1|AAK17998.1| 446|Homo sapiens glutamate rich WD repea... 45 2e-04
AF127799-1|AAP97249.1| 305|Homo sapiens G protein beta subunit-... 45 2e-04
U02609-1|AAA18945.1| 519|Homo sapiens transducin-like protein p... 45 3e-04
BC068499-1|AAH68499.1| 351|Homo sapiens THO complex 3 protein. 45 3e-04
BC066325-1|AAH66325.1| 327|Homo sapiens THOC3 protein protein. 45 3e-04
BC006849-1|AAH06849.1| 351|Homo sapiens THO complex 3 protein. 45 3e-04
AF080397-1|AAF20266.1| 493|Homo sapiens fizzy-related protein h... 45 3e-04
U05340-1|AAA19017.1| 499|Homo sapiens p55CDC protein. 44 4e-04
DQ870924-1|ABI74670.1| 1269|Homo sapiens activating molecule in ... 44 4e-04
DQ473545-1|ABE96834.1| 499|Homo sapiens CDC20 cell division cyc... 44 4e-04
BT007388-1|AAP36052.1| 499|Homo sapiens CDC20 cell division cyc... 44 4e-04
BC117291-1|AAI17292.1| 925|Homo sapiens coronin 7 protein. 44 4e-04
BC117289-1|AAI17290.1| 925|Homo sapiens coronin 7 protein. 44 4e-04
BC110321-1|AAI10322.1| 499|Homo sapiens cell division cycle 20 ... 44 4e-04
BC088354-1|AAH88354.1| 326|Homo sapiens G protein beta subunit-... 44 4e-04
BC052292-1|AAH52292.1| 326|Homo sapiens GBL protein protein. 44 4e-04
BC045609-1|AAH45609.1| 1208|Homo sapiens hypothetical protein FL... 44 4e-04
BC031294-1|AAH31294.1| 499|Homo sapiens cell division cycle 20 ... 44 4e-04
BC024257-1|AAH24257.1| 499|Homo sapiens cell division cycle 20 ... 44 4e-04
BC020499-1|AAH20499.1| 327|Homo sapiens GBL protein protein. 44 4e-04
BC017119-1|AAH17119.1| 326|Homo sapiens G protein beta subunit-... 44 4e-04
BC015998-1|AAH15998.1| 499|Homo sapiens cell division cycle 20 ... 44 4e-04
BC013303-1|AAH13303.1| 499|Homo sapiens cell division cycle 20 ... 44 4e-04
BC012827-1|AAH12827.1| 499|Homo sapiens cell division cycle 20 ... 44 4e-04
BC012803-1|AAH12803.1| 499|Homo sapiens cell division cycle 20 ... 44 4e-04
BC010044-1|AAH10044.1| 499|Homo sapiens cell division cycle 20 ... 44 4e-04
BC009426-1|AAH09426.1| 499|Homo sapiens cell division cycle 20 ... 44 4e-04
BC009425-1|AAH09425.1| 499|Homo sapiens cell division cycle 20 ... 44 4e-04
BC006272-1|AAH06272.1| 499|Homo sapiens cell division cycle 20 ... 44 4e-04
BC001313-1|AAH01313.1| 326|Homo sapiens G protein beta subunit-... 44 4e-04
BC001088-1|AAH01088.1| 499|Homo sapiens cell division cycle 20 ... 44 4e-04
BC000624-1|AAH00624.1| 499|Homo sapiens CDC20 protein protein. 44 4e-04
AL139289-3|CAB92757.1| 499|Homo sapiens cell division cycle 20 ... 44 4e-04
AK025674-1|BAB15211.1| 925|Homo sapiens protein ( Homo sapiens ... 44 4e-04
AK000301-1|BAA91067.1| 687|Homo sapiens protein ( Homo sapiens ... 44 4e-04
AF099644-1|AAD16405.1| 499|Homo sapiens cell cycle protein CDC2... 44 4e-04
AB051523-1|BAB21827.1| 1244|Homo sapiens KIAA1736 protein protein. 44 4e-04
BC022967-1|AAH22967.1| 326|Homo sapiens WDR22 protein protein. 44 6e-04
BC014004-1|AAH14004.1| 400|Homo sapiens WD repeat and FYVE doma... 44 6e-04
AL139183-1|CAH73431.1| 400|Homo sapiens WD repeat and FYVE doma... 44 6e-04
AL136525-1|CAH70585.1| 400|Homo sapiens WD repeat and FYVE doma... 44 6e-04
AK058149-1|BAB71687.1| 297|Homo sapiens protein ( Homo sapiens ... 44 6e-04
AB058727-1|BAB47453.1| 958|Homo sapiens KIAA1824 protein protein. 44 6e-04
U86136-1|AAC51107.1| 2627|Homo sapiens telomerase-associated pro... 44 7e-04
BC126107-1|AAI26108.1| 2627|Homo sapiens telomerase-associated p... 44 7e-04
BC106879-1|AAI06880.1| 731|Homo sapiens STRN protein protein. 44 7e-04
>M24194-1|AAA59626.1| 317|Homo sapiens MHC B complex protein 12.3
protein.
Length = 317
Score = 351 bits (863), Expect = 1e-96
Identities = 152/197 (77%), Positives = 173/197 (87%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
GSRDKTIKLWNTL CKYT+QD+ HS+WVSCVRFSPN +NPIIVSCGWD+ VKVW+L NC
Sbjct: 123 GSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANC 182
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDIITALCFS 359
KLK NH+GH+GYLNTVTVSPDGSLCASGGKD +AMLWDLN+GKHL+TLD DII ALCFS
Sbjct: 183 KLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCFS 242
Query: 358 PNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFA 179
PNRYWLCAA GPSIKIWDLE K +V+EL+ E+I + +SK +PPQC SLAWS DGQTLFA
Sbjct: 243 PNRYWLCAATGPSIKIWDLEGKIIVDELKQEVI--STSSKAEPPQCTSLAWSADGQTLFA 300
Query: 178 GYSDNTIRVWQVSISAR 128
GY+DN +RVWQV+I R
Sbjct: 301 GYTDNLVRVWQVTIGTR 317
Score = 59.7 bits (138), Expect = 1e-08
Identities = 54/189 (28%), Positives = 84/189 (44%), Gaps = 12/189 (6%)
Frame = -2
Query: 715 SRDKTIKLWN-TLAECKYTIQDD---GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHL 548
SRDKTI +W T E Y I GHS +VS V S + +S WD T+++W L
Sbjct: 35 SRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSD--GQFALSGSWDGTLRLWDL 92
Query: 547 TNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWD-LNDGKH-LHTLDHNDIIT 374
T +GH+ + +V S D SG +D LW+ L K+ + H++ ++
Sbjct: 93 TTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVS 152
Query: 373 ALCFSPNR---YWLCAAFGPSIKIWDLESKEMVEELRPEIINQT---QTSKTDPPQCLSL 212
+ FSPN + + +K+W+L + +L+ I T T P L
Sbjct: 153 CVRFSPNSSNPIIVSCGWDKLVKVWNLANC----KLKTNHIGHTGYLNTVTVSPDGSLCA 208
Query: 211 AWSTDGQTL 185
+ DGQ +
Sbjct: 209 SGGKDGQAM 217
>CR541909-1|CAG46707.1| 317|Homo sapiens GNB2L1 protein.
Length = 317
Score = 351 bits (863), Expect = 1e-96
Identities = 152/197 (77%), Positives = 173/197 (87%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
GSRDKTIKLWNTL CKYT+QD+ HS+WVSCVRFSPN +NPIIVSCGWD+ VKVW+L NC
Sbjct: 123 GSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANC 182
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDIITALCFS 359
KLK NH+GH+GYLNTVTVSPDGSLCASGGKD +AMLWDLN+GKHL+TLD DII ALCFS
Sbjct: 183 KLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCFS 242
Query: 358 PNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFA 179
PNRYWLCAA GPSIKIWDLE K +V+EL+ E+I + +SK +PPQC SLAWS DGQTLFA
Sbjct: 243 PNRYWLCAATGPSIKIWDLEGKIIVDELKQEVI--STSSKAEPPQCTSLAWSADGQTLFA 300
Query: 178 GYSDNTIRVWQVSISAR 128
GY+DN +RVWQV+I R
Sbjct: 301 GYTDNLVRVWQVTIGTR 317
Score = 59.7 bits (138), Expect = 1e-08
Identities = 54/189 (28%), Positives = 84/189 (44%), Gaps = 12/189 (6%)
Frame = -2
Query: 715 SRDKTIKLWN-TLAECKYTIQDD---GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHL 548
SRDKTI +W T E Y I GHS +VS V S + +S WD T+++W L
Sbjct: 35 SRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSD--GQFALSGSWDGTLRLWDL 92
Query: 547 TNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWD-LNDGKH-LHTLDHNDIIT 374
T +GH+ + +V S D SG +D LW+ L K+ + H++ ++
Sbjct: 93 TTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVS 152
Query: 373 ALCFSPNR---YWLCAAFGPSIKIWDLESKEMVEELRPEIINQT---QTSKTDPPQCLSL 212
+ FSPN + + +K+W+L + +L+ I T T P L
Sbjct: 153 CVRFSPNSSNPIIVSCGWDKLVKVWNLANC----KLKTNHIGHTGYLNTVTVSPDGSLCA 208
Query: 211 AWSTDGQTL 185
+ DGQ +
Sbjct: 209 SGGKDGQAM 217
>CR456978-1|CAG33259.1| 317|Homo sapiens GNB2L1 protein.
Length = 317
Score = 351 bits (863), Expect = 1e-96
Identities = 152/197 (77%), Positives = 173/197 (87%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
GSRDKTIKLWNTL CKYT+QD+ HS+WVSCVRFSPN +NPIIVSCGWD+ VKVW+L NC
Sbjct: 123 GSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANC 182
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDIITALCFS 359
KLK NH+GH+GYLNTVTVSPDGSLCASGGKD +AMLWDLN+GKHL+TLD DII ALCFS
Sbjct: 183 KLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCFS 242
Query: 358 PNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFA 179
PNRYWLCAA GPSIKIWDLE K +V+EL+ E+I + +SK +PPQC SLAWS DGQTLFA
Sbjct: 243 PNRYWLCAATGPSIKIWDLEGKIIVDELKQEVI--STSSKAEPPQCTSLAWSADGQTLFA 300
Query: 178 GYSDNTIRVWQVSISAR 128
GY+DN +RVWQV+I R
Sbjct: 301 GYTDNLVRVWQVTIGTR 317
Score = 59.7 bits (138), Expect = 1e-08
Identities = 54/189 (28%), Positives = 84/189 (44%), Gaps = 12/189 (6%)
Frame = -2
Query: 715 SRDKTIKLWN-TLAECKYTIQDD---GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHL 548
SRDKTI +W T E Y I GHS +VS V S + +S WD T+++W L
Sbjct: 35 SRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSD--GQFALSGSWDGTLRLWDL 92
Query: 547 TNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWD-LNDGKH-LHTLDHNDIIT 374
T +GH+ + +V S D SG +D LW+ L K+ + H++ ++
Sbjct: 93 TTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVS 152
Query: 373 ALCFSPNR---YWLCAAFGPSIKIWDLESKEMVEELRPEIINQT---QTSKTDPPQCLSL 212
+ FSPN + + +K+W+L + +L+ I T T P L
Sbjct: 153 CVRFSPNSSNPIIVSCGWDKLVKVWNLANC----KLKTNHIGHTGYLNTVTVSPDGSLCA 208
Query: 211 AWSTDGQTL 185
+ DGQ +
Sbjct: 209 SGGKDGQAM 217
>BC032006-1|AAH32006.1| 317|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2-like 1 protein.
Length = 317
Score = 351 bits (863), Expect = 1e-96
Identities = 152/197 (77%), Positives = 173/197 (87%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
GSRDKTIKLWNTL CKYT+QD+ HS+WVSCVRFSPN +NPIIVSCGWD+ VKVW+L NC
Sbjct: 123 GSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANC 182
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDIITALCFS 359
KLK NH+GH+GYLNTVTVSPDGSLCASGGKD +AMLWDLN+GKHL+TLD DII ALCFS
Sbjct: 183 KLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCFS 242
Query: 358 PNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFA 179
PNRYWLCAA GPSIKIWDLE K +V+EL+ E+I + +SK +PPQC SLAWS DGQTLFA
Sbjct: 243 PNRYWLCAATGPSIKIWDLEGKIIVDELKQEVI--STSSKAEPPQCTSLAWSADGQTLFA 300
Query: 178 GYSDNTIRVWQVSISAR 128
GY+DN +RVWQV+I R
Sbjct: 301 GYTDNLVRVWQVTIGTR 317
Score = 59.7 bits (138), Expect = 1e-08
Identities = 54/189 (28%), Positives = 84/189 (44%), Gaps = 12/189 (6%)
Frame = -2
Query: 715 SRDKTIKLWN-TLAECKYTIQDD---GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHL 548
SRDKTI +W T E Y I GHS +VS V S + +S WD T+++W L
Sbjct: 35 SRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSD--GQFALSGSWDGTLRLWDL 92
Query: 547 TNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWD-LNDGKH-LHTLDHNDIIT 374
T +GH+ + +V S D SG +D LW+ L K+ + H++ ++
Sbjct: 93 TTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVS 152
Query: 373 ALCFSPNR---YWLCAAFGPSIKIWDLESKEMVEELRPEIINQT---QTSKTDPPQCLSL 212
+ FSPN + + +K+W+L + +L+ I T T P L
Sbjct: 153 CVRFSPNSSNPIIVSCGWDKLVKVWNLANC----KLKTNHIGHTGYLNTVTVSPDGSLCA 208
Query: 211 AWSTDGQTL 185
+ DGQ +
Sbjct: 209 SGGKDGQAM 217
>BC021993-1|AAH21993.1| 317|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2-like 1 protein.
Length = 317
Score = 351 bits (863), Expect = 1e-96
Identities = 152/197 (77%), Positives = 173/197 (87%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
GSRDKTIKLWNTL CKYT+QD+ HS+WVSCVRFSPN +NPIIVSCGWD+ VKVW+L NC
Sbjct: 123 GSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANC 182
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDIITALCFS 359
KLK NH+GH+GYLNTVTVSPDGSLCASGGKD +AMLWDLN+GKHL+TLD DII ALCFS
Sbjct: 183 KLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCFS 242
Query: 358 PNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFA 179
PNRYWLCAA GPSIKIWDLE K +V+EL+ E+I + +SK +PPQC SLAWS DGQTLFA
Sbjct: 243 PNRYWLCAATGPSIKIWDLEGKIIVDELKQEVI--STSSKAEPPQCTSLAWSADGQTLFA 300
Query: 178 GYSDNTIRVWQVSISAR 128
GY+DN +RVWQV+I R
Sbjct: 301 GYTDNLVRVWQVTIGTR 317
Score = 59.7 bits (138), Expect = 1e-08
Identities = 54/189 (28%), Positives = 84/189 (44%), Gaps = 12/189 (6%)
Frame = -2
Query: 715 SRDKTIKLWN-TLAECKYTIQDD---GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHL 548
SRDKTI +W T E Y I GHS +VS V S + +S WD T+++W L
Sbjct: 35 SRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSD--GQFALSGSWDGTLRLWDL 92
Query: 547 TNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWD-LNDGKH-LHTLDHNDIIT 374
T +GH+ + +V S D SG +D LW+ L K+ + H++ ++
Sbjct: 93 TTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVS 152
Query: 373 ALCFSPNR---YWLCAAFGPSIKIWDLESKEMVEELRPEIINQT---QTSKTDPPQCLSL 212
+ FSPN + + +K+W+L + +L+ I T T P L
Sbjct: 153 CVRFSPNSSNPIIVSCGWDKLVKVWNLANC----KLKTNHIGHTGYLNTVTVSPDGSLCA 208
Query: 211 AWSTDGQTL 185
+ DGQ +
Sbjct: 209 SGGKDGQAM 217
>BC019362-1|AAH19362.1| 317|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2-like 1 protein.
Length = 317
Score = 351 bits (863), Expect = 1e-96
Identities = 152/197 (77%), Positives = 173/197 (87%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
GSRDKTIKLWNTL CKYT+QD+ HS+WVSCVRFSPN +NPIIVSCGWD+ VKVW+L NC
Sbjct: 123 GSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANC 182
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDIITALCFS 359
KLK NH+GH+GYLNTVTVSPDGSLCASGGKD +AMLWDLN+GKHL+TLD DII ALCFS
Sbjct: 183 KLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCFS 242
Query: 358 PNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFA 179
PNRYWLCAA GPSIKIWDLE K +V+EL+ E+I + +SK +PPQC SLAWS DGQTLFA
Sbjct: 243 PNRYWLCAATGPSIKIWDLEGKIIVDELKQEVI--STSSKAEPPQCTSLAWSADGQTLFA 300
Query: 178 GYSDNTIRVWQVSISAR 128
GY+DN +RVWQV+I R
Sbjct: 301 GYTDNLVRVWQVTIGTR 317
Score = 59.7 bits (138), Expect = 1e-08
Identities = 54/189 (28%), Positives = 84/189 (44%), Gaps = 12/189 (6%)
Frame = -2
Query: 715 SRDKTIKLWN-TLAECKYTIQDD---GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHL 548
SRDKTI +W T E Y I GHS +VS V S + +S WD T+++W L
Sbjct: 35 SRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSD--GQFALSGSWDGTLRLWDL 92
Query: 547 TNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWD-LNDGKH-LHTLDHNDIIT 374
T +GH+ + +V S D SG +D LW+ L K+ + H++ ++
Sbjct: 93 TTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVS 152
Query: 373 ALCFSPNR---YWLCAAFGPSIKIWDLESKEMVEELRPEIINQT---QTSKTDPPQCLSL 212
+ FSPN + + +K+W+L + +L+ I T T P L
Sbjct: 153 CVRFSPNSSNPIIVSCGWDKLVKVWNLANC----KLKTNHIGHTGYLNTVTVSPDGSLCA 208
Query: 211 AWSTDGQTL 185
+ DGQ +
Sbjct: 209 SGGKDGQAM 217
>BC019093-1|AAH19093.1| 317|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2-like 1 protein.
Length = 317
Score = 351 bits (863), Expect = 1e-96
Identities = 152/197 (77%), Positives = 173/197 (87%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
GSRDKTIKLWNTL CKYT+QD+ HS+WVSCVRFSPN +NPIIVSCGWD+ VKVW+L NC
Sbjct: 123 GSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANC 182
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDIITALCFS 359
KLK NH+GH+GYLNTVTVSPDGSLCASGGKD +AMLWDLN+GKHL+TLD DII ALCFS
Sbjct: 183 KLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCFS 242
Query: 358 PNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFA 179
PNRYWLCAA GPSIKIWDLE K +V+EL+ E+I + +SK +PPQC SLAWS DGQTLFA
Sbjct: 243 PNRYWLCAATGPSIKIWDLEGKIIVDELKQEVI--STSSKAEPPQCTSLAWSADGQTLFA 300
Query: 178 GYSDNTIRVWQVSISAR 128
GY+DN +RVWQV+I R
Sbjct: 301 GYTDNLVRVWQVTIGTR 317
Score = 59.7 bits (138), Expect = 1e-08
Identities = 54/189 (28%), Positives = 84/189 (44%), Gaps = 12/189 (6%)
Frame = -2
Query: 715 SRDKTIKLWN-TLAECKYTIQDD---GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHL 548
SRDKTI +W T E Y I GHS +VS V S + +S WD T+++W L
Sbjct: 35 SRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSD--GQFALSGSWDGTLRLWDL 92
Query: 547 TNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWD-LNDGKH-LHTLDHNDIIT 374
T +GH+ + +V S D SG +D LW+ L K+ + H++ ++
Sbjct: 93 TTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVS 152
Query: 373 ALCFSPNR---YWLCAAFGPSIKIWDLESKEMVEELRPEIINQT---QTSKTDPPQCLSL 212
+ FSPN + + +K+W+L + +L+ I T T P L
Sbjct: 153 CVRFSPNSSNPIIVSCGWDKLVKVWNLANC----KLKTNHIGHTGYLNTVTVSPDGSLCA 208
Query: 211 AWSTDGQTL 185
+ DGQ +
Sbjct: 209 SGGKDGQAM 217
>BC017287-1|AAH17287.1| 317|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2-like 1 protein.
Length = 317
Score = 351 bits (863), Expect = 1e-96
Identities = 152/197 (77%), Positives = 173/197 (87%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
GSRDKTIKLWNTL CKYT+QD+ HS+WVSCVRFSPN +NPIIVSCGWD+ VKVW+L NC
Sbjct: 123 GSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANC 182
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDIITALCFS 359
KLK NH+GH+GYLNTVTVSPDGSLCASGGKD +AMLWDLN+GKHL+TLD DII ALCFS
Sbjct: 183 KLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCFS 242
Query: 358 PNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFA 179
PNRYWLCAA GPSIKIWDLE K +V+EL+ E+I + +SK +PPQC SLAWS DGQTLFA
Sbjct: 243 PNRYWLCAATGPSIKIWDLEGKIIVDELKQEVI--STSSKAEPPQCTSLAWSADGQTLFA 300
Query: 178 GYSDNTIRVWQVSISAR 128
GY+DN +RVWQV+I R
Sbjct: 301 GYTDNLVRVWQVTIGTR 317
Score = 59.7 bits (138), Expect = 1e-08
Identities = 54/189 (28%), Positives = 84/189 (44%), Gaps = 12/189 (6%)
Frame = -2
Query: 715 SRDKTIKLWN-TLAECKYTIQDD---GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHL 548
SRDKTI +W T E Y I GHS +VS V S + +S WD T+++W L
Sbjct: 35 SRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSD--GQFALSGSWDGTLRLWDL 92
Query: 547 TNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWD-LNDGKH-LHTLDHNDIIT 374
T +GH+ + +V S D SG +D LW+ L K+ + H++ ++
Sbjct: 93 TTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVS 152
Query: 373 ALCFSPNR---YWLCAAFGPSIKIWDLESKEMVEELRPEIINQT---QTSKTDPPQCLSL 212
+ FSPN + + +K+W+L + +L+ I T T P L
Sbjct: 153 CVRFSPNSSNPIIVSCGWDKLVKVWNLANC----KLKTNHIGHTGYLNTVTVSPDGSLCA 208
Query: 211 AWSTDGQTL 185
+ DGQ +
Sbjct: 209 SGGKDGQAM 217
>BC014788-1|AAH14788.1| 317|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2-like 1 protein.
Length = 317
Score = 351 bits (863), Expect = 1e-96
Identities = 152/197 (77%), Positives = 173/197 (87%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
GSRDKTIKLWNTL CKYT+QD+ HS+WVSCVRFSPN +NPIIVSCGWD+ VKVW+L NC
Sbjct: 123 GSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANC 182
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDIITALCFS 359
KLK NH+GH+GYLNTVTVSPDGSLCASGGKD +AMLWDLN+GKHL+TLD DII ALCFS
Sbjct: 183 KLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCFS 242
Query: 358 PNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFA 179
PNRYWLCAA GPSIKIWDLE K +V+EL+ E+I + +SK +PPQC SLAWS DGQTLFA
Sbjct: 243 PNRYWLCAATGPSIKIWDLEGKIIVDELKQEVI--STSSKAEPPQCTSLAWSADGQTLFA 300
Query: 178 GYSDNTIRVWQVSISAR 128
GY+DN +RVWQV+I R
Sbjct: 301 GYTDNLVRVWQVTIGTR 317
Score = 59.7 bits (138), Expect = 1e-08
Identities = 54/189 (28%), Positives = 84/189 (44%), Gaps = 12/189 (6%)
Frame = -2
Query: 715 SRDKTIKLWN-TLAECKYTIQDD---GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHL 548
SRDKTI +W T E Y I GHS +VS V S + +S WD T+++W L
Sbjct: 35 SRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSD--GQFALSGSWDGTLRLWDL 92
Query: 547 TNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWD-LNDGKH-LHTLDHNDIIT 374
T +GH+ + +V S D SG +D LW+ L K+ + H++ ++
Sbjct: 93 TTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVS 152
Query: 373 ALCFSPNR---YWLCAAFGPSIKIWDLESKEMVEELRPEIINQT---QTSKTDPPQCLSL 212
+ FSPN + + +K+W+L + +L+ I T T P L
Sbjct: 153 CVRFSPNSSNPIIVSCGWDKLVKVWNLANC----KLKTNHIGHTGYLNTVTVSPDGSLCA 208
Query: 211 AWSTDGQTL 185
+ DGQ +
Sbjct: 209 SGGKDGQAM 217
>BC014256-1|AAH14256.1| 317|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2-like 1 protein.
Length = 317
Score = 351 bits (863), Expect = 1e-96
Identities = 152/197 (77%), Positives = 173/197 (87%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
GSRDKTIKLWNTL CKYT+QD+ HS+WVSCVRFSPN +NPIIVSCGWD+ VKVW+L NC
Sbjct: 123 GSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANC 182
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDIITALCFS 359
KLK NH+GH+GYLNTVTVSPDGSLCASGGKD +AMLWDLN+GKHL+TLD DII ALCFS
Sbjct: 183 KLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCFS 242
Query: 358 PNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFA 179
PNRYWLCAA GPSIKIWDLE K +V+EL+ E+I + +SK +PPQC SLAWS DGQTLFA
Sbjct: 243 PNRYWLCAATGPSIKIWDLEGKIIVDELKQEVI--STSSKAEPPQCTSLAWSADGQTLFA 300
Query: 178 GYSDNTIRVWQVSISAR 128
GY+DN +RVWQV+I R
Sbjct: 301 GYTDNLVRVWQVTIGTR 317
Score = 59.7 bits (138), Expect = 1e-08
Identities = 54/189 (28%), Positives = 84/189 (44%), Gaps = 12/189 (6%)
Frame = -2
Query: 715 SRDKTIKLWN-TLAECKYTIQDD---GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHL 548
SRDKTI +W T E Y I GHS +VS V S + +S WD T+++W L
Sbjct: 35 SRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSD--GQFALSGSWDGTLRLWDL 92
Query: 547 TNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWD-LNDGKH-LHTLDHNDIIT 374
T +GH+ + +V S D SG +D LW+ L K+ + H++ ++
Sbjct: 93 TTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVS 152
Query: 373 ALCFSPNR---YWLCAAFGPSIKIWDLESKEMVEELRPEIINQT---QTSKTDPPQCLSL 212
+ FSPN + + +K+W+L + +L+ I T T P L
Sbjct: 153 CVRFSPNSSNPIIVSCGWDKLVKVWNLANC----KLKTNHIGHTGYLNTVTVSPDGSLCA 208
Query: 211 AWSTDGQTL 185
+ DGQ +
Sbjct: 209 SGGKDGQAM 217
>BC010119-1|AAH10119.1| 317|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2-like 1 protein.
Length = 317
Score = 351 bits (863), Expect = 1e-96
Identities = 152/197 (77%), Positives = 173/197 (87%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
GSRDKTIKLWNTL CKYT+QD+ HS+WVSCVRFSPN +NPIIVSCGWD+ VKVW+L NC
Sbjct: 123 GSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANC 182
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDIITALCFS 359
KLK NH+GH+GYLNTVTVSPDGSLCASGGKD +AMLWDLN+GKHL+TLD DII ALCFS
Sbjct: 183 KLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCFS 242
Query: 358 PNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFA 179
PNRYWLCAA GPSIKIWDLE K +V+EL+ E+I + +SK +PPQC SLAWS DGQTLFA
Sbjct: 243 PNRYWLCAATGPSIKIWDLEGKIIVDELKQEVI--STSSKAEPPQCTSLAWSADGQTLFA 300
Query: 178 GYSDNTIRVWQVSISAR 128
GY+DN +RVWQV+I R
Sbjct: 301 GYTDNLVRVWQVTIGTR 317
Score = 59.7 bits (138), Expect = 1e-08
Identities = 54/189 (28%), Positives = 84/189 (44%), Gaps = 12/189 (6%)
Frame = -2
Query: 715 SRDKTIKLWN-TLAECKYTIQDD---GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHL 548
SRDKTI +W T E Y I GHS +VS V S + +S WD T+++W L
Sbjct: 35 SRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSD--GQFALSGSWDGTLRLWDL 92
Query: 547 TNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWD-LNDGKH-LHTLDHNDIIT 374
T +GH+ + +V S D SG +D LW+ L K+ + H++ ++
Sbjct: 93 TTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVS 152
Query: 373 ALCFSPNR---YWLCAAFGPSIKIWDLESKEMVEELRPEIINQT---QTSKTDPPQCLSL 212
+ FSPN + + +K+W+L + +L+ I T T P L
Sbjct: 153 CVRFSPNSSNPIIVSCGWDKLVKVWNLANC----KLKTNHIGHTGYLNTVTVSPDGSLCA 208
Query: 211 AWSTDGQTL 185
+ DGQ +
Sbjct: 209 SGGKDGQAM 217
>BC000366-1|AAH00366.1| 317|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2-like 1 protein.
Length = 317
Score = 351 bits (863), Expect = 1e-96
Identities = 152/197 (77%), Positives = 173/197 (87%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
GSRDKTIKLWNTL CKYT+QD+ HS+WVSCVRFSPN +NPIIVSCGWD+ VKVW+L NC
Sbjct: 123 GSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANC 182
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDIITALCFS 359
KLK NH+GH+GYLNTVTVSPDGSLCASGGKD +AMLWDLN+GKHL+TLD DII ALCFS
Sbjct: 183 KLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCFS 242
Query: 358 PNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFA 179
PNRYWLCAA GPSIKIWDLE K +V+EL+ E+I + +SK +PPQC SLAWS DGQTLFA
Sbjct: 243 PNRYWLCAATGPSIKIWDLEGKIIVDELKQEVI--STSSKAEPPQCTSLAWSADGQTLFA 300
Query: 178 GYSDNTIRVWQVSISAR 128
GY+DN +RVWQV+I R
Sbjct: 301 GYTDNLVRVWQVTIGTR 317
Score = 59.7 bits (138), Expect = 1e-08
Identities = 54/189 (28%), Positives = 84/189 (44%), Gaps = 12/189 (6%)
Frame = -2
Query: 715 SRDKTIKLWN-TLAECKYTIQDD---GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHL 548
SRDKTI +W T E Y I GHS +VS V S + +S WD T+++W L
Sbjct: 35 SRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSD--GQFALSGSWDGTLRLWDL 92
Query: 547 TNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWD-LNDGKH-LHTLDHNDIIT 374
T +GH+ + +V S D SG +D LW+ L K+ + H++ ++
Sbjct: 93 TTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVS 152
Query: 373 ALCFSPNR---YWLCAAFGPSIKIWDLESKEMVEELRPEIINQT---QTSKTDPPQCLSL 212
+ FSPN + + +K+W+L + +L+ I T T P L
Sbjct: 153 CVRFSPNSSNPIIVSCGWDKLVKVWNLANC----KLKTNHIGHTGYLNTVTVSPDGSLCA 208
Query: 211 AWSTDGQTL 185
+ DGQ +
Sbjct: 209 SGGKDGQAM 217
>BC000214-1|AAH00214.1| 317|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2-like 1 protein.
Length = 317
Score = 351 bits (863), Expect = 1e-96
Identities = 152/197 (77%), Positives = 173/197 (87%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
GSRDKTIKLWNTL CKYT+QD+ HS+WVSCVRFSPN +NPIIVSCGWD+ VKVW+L NC
Sbjct: 123 GSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANC 182
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDIITALCFS 359
KLK NH+GH+GYLNTVTVSPDGSLCASGGKD +AMLWDLN+GKHL+TLD DII ALCFS
Sbjct: 183 KLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCFS 242
Query: 358 PNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFA 179
PNRYWLCAA GPSIKIWDLE K +V+EL+ E+I + +SK +PPQC SLAWS DGQTLFA
Sbjct: 243 PNRYWLCAATGPSIKIWDLEGKIIVDELKQEVI--STSSKAEPPQCTSLAWSADGQTLFA 300
Query: 178 GYSDNTIRVWQVSISAR 128
GY+DN +RVWQV+I R
Sbjct: 301 GYTDNLVRVWQVTIGTR 317
Score = 59.7 bits (138), Expect = 1e-08
Identities = 54/189 (28%), Positives = 84/189 (44%), Gaps = 12/189 (6%)
Frame = -2
Query: 715 SRDKTIKLWN-TLAECKYTIQDD---GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHL 548
SRDKTI +W T E Y I GHS +VS V S + +S WD T+++W L
Sbjct: 35 SRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSD--GQFALSGSWDGTLRLWDL 92
Query: 547 TNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWD-LNDGKH-LHTLDHNDIIT 374
T +GH+ + +V S D SG +D LW+ L K+ + H++ ++
Sbjct: 93 TTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVS 152
Query: 373 ALCFSPNR---YWLCAAFGPSIKIWDLESKEMVEELRPEIINQT---QTSKTDPPQCLSL 212
+ FSPN + + +K+W+L + +L+ I T T P L
Sbjct: 153 CVRFSPNSSNPIIVSCGWDKLVKVWNLANC----KLKTNHIGHTGYLNTVTVSPDGSLCA 208
Query: 211 AWSTDGQTL 185
+ DGQ +
Sbjct: 209 SGGKDGQAM 217
>AY336089-1|AAR24619.1| 271|Homo sapiens proliferation-inducing
gene 21 protein.
Length = 271
Score = 351 bits (863), Expect = 1e-96
Identities = 152/197 (77%), Positives = 173/197 (87%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
GSRDKTIKLWNTL CKYT+QD+ HS+WVSCVRFSPN +NPIIVSCGWD+ VKVW+L NC
Sbjct: 77 GSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANC 136
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDIITALCFS 359
KLK NH+GH+GYLNTVTVSPDGSLCASGGKD +AMLWDLN+GKHL+TLD DII ALCFS
Sbjct: 137 KLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCFS 196
Query: 358 PNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFA 179
PNRYWLCAA GPSIKIWDLE K +V+EL+ E+I + +SK +PPQC SLAWS DGQTLFA
Sbjct: 197 PNRYWLCAATGPSIKIWDLEGKIIVDELKQEVI--STSSKAEPPQCTSLAWSADGQTLFA 254
Query: 178 GYSDNTIRVWQVSISAR 128
GY+DN +RVWQV+I R
Sbjct: 255 GYTDNLVRVWQVTIGTR 271
Score = 51.2 bits (117), Expect = 4e-06
Identities = 44/138 (31%), Positives = 68/138 (49%), Gaps = 7/138 (5%)
Frame = -2
Query: 649 GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWH-LTNCKLKINHLGHSGYLNTVTVSPDG 473
GH+ V V FS + N IVS D+T+K+W+ L CK + HS +++ V SP+
Sbjct: 57 GHTKDVLSVAFSSD--NRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNS 114
Query: 472 S--LCASGGKDMKAMLWDLNDGK-HLHTLDHNDIITALCFSPNRYWLCAAFGP--SIKIW 308
S + S G D +W+L + K + + H + + SP+ LCA+ G +W
Sbjct: 115 SNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGS-LCASGGKDGQAMLW 173
Query: 307 DL-ESKEMVEELRPEIIN 257
DL E K + +IIN
Sbjct: 174 DLNEGKHLYTLDGGDIIN 191
Score = 30.7 bits (66), Expect = 5.5
Identities = 29/120 (24%), Positives = 52/120 (43%), Gaps = 8/120 (6%)
Frame = -2
Query: 520 LGHSGYLNTVTVSPDGSLCASGGKDMKAMLWD-LNDGKH-LHTLDHNDIITALCFSPNR- 350
+GH+ + +V S D SG +D LW+ L K+ + H++ ++ + FSPN
Sbjct: 56 VGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSS 115
Query: 349 --YWLCAAFGPSIKIWDLESKEMVEELRPEIINQT---QTSKTDPPQCLSLAWSTDGQTL 185
+ + +K+W+L + +L+ I T T P L + DGQ +
Sbjct: 116 NPIIVSCGWDKLVKVWNLANC----KLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAM 171
>AY159316-1|AAO21313.1| 347|Homo sapiens lung cancer oncogene 7
protein.
Length = 347
Score = 351 bits (863), Expect = 1e-96
Identities = 152/197 (77%), Positives = 173/197 (87%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
GSRDKTIKLWNTL CKYT+QD+ HS+WVSCVRFSPN +NPIIVSCGWD+ VKVW+L NC
Sbjct: 153 GSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANC 212
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDIITALCFS 359
KLK NH+GH+GYLNTVTVSPDGSLCASGGKD +AMLWDLN+GKHL+TLD DII ALCFS
Sbjct: 213 KLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCFS 272
Query: 358 PNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFA 179
PNRYWLCAA GPSIKIWDLE K +V+EL+ E+I + +SK +PPQC SLAWS DGQTLFA
Sbjct: 273 PNRYWLCAATGPSIKIWDLEGKIIVDELKQEVI--STSSKAEPPQCTSLAWSADGQTLFA 330
Query: 178 GYSDNTIRVWQVSISAR 128
GY+DN +RVWQV+I R
Sbjct: 331 GYTDNLVRVWQVTIGTR 347
Score = 59.7 bits (138), Expect = 1e-08
Identities = 54/189 (28%), Positives = 84/189 (44%), Gaps = 12/189 (6%)
Frame = -2
Query: 715 SRDKTIKLWN-TLAECKYTIQDD---GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHL 548
SRDKTI +W T E Y I GHS +VS V S + +S WD T+++W L
Sbjct: 65 SRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSD--GQFALSGSWDGTLRLWDL 122
Query: 547 TNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWD-LNDGKH-LHTLDHNDIIT 374
T +GH+ + +V S D SG +D LW+ L K+ + H++ ++
Sbjct: 123 TTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVS 182
Query: 373 ALCFSPNR---YWLCAAFGPSIKIWDLESKEMVEELRPEIINQT---QTSKTDPPQCLSL 212
+ FSPN + + +K+W+L + +L+ I T T P L
Sbjct: 183 CVRFSPNSSNPIIVSCGWDKLVKVWNLANC----KLKTNHIGHTGYLNTVTVSPDGSLCA 238
Query: 211 AWSTDGQTL 185
+ DGQ +
Sbjct: 239 SGGKDGQAM 247
>AK222488-1|BAD96208.1| 317|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2-like 1 varia
protein.
Length = 317
Score = 349 bits (859), Expect = 4e-96
Identities = 151/197 (76%), Positives = 172/197 (87%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
GSRDKTIKLWNTL CKYT+QD+ HS+WVSCVRFSPN +NPIIVSCGWD+ VKVW+L NC
Sbjct: 123 GSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANC 182
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDIITALCFS 359
KLK NH+GH+GYLNTVTVSPDGSLCASGGKD +AMLWD N+GKHL+TLD DII ALCFS
Sbjct: 183 KLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDFNEGKHLYTLDGGDIINALCFS 242
Query: 358 PNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFA 179
PNRYWLCAA GPSIKIWDLE K +V+EL+ E+I + +SK +PPQC SLAWS DGQTLFA
Sbjct: 243 PNRYWLCAATGPSIKIWDLEGKIIVDELKQEVI--STSSKAEPPQCTSLAWSADGQTLFA 300
Query: 178 GYSDNTIRVWQVSISAR 128
GY+DN +RVWQV+I R
Sbjct: 301 GYTDNLVRVWQVTIGTR 317
Score = 60.5 bits (140), Expect = 6e-09
Identities = 54/195 (27%), Positives = 87/195 (44%), Gaps = 12/195 (6%)
Frame = -2
Query: 715 SRDKTIKLWN-TLAECKYTIQDD---GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHL 548
SRDKTI +W T E Y I GHS +VS V S + +S WD T+++W L
Sbjct: 35 SRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSD--GQFALSGSWDGTLRLWDL 92
Query: 547 TNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWD-LNDGKH-LHTLDHNDIIT 374
T +GH+ + +V S D SG +D LW+ L K+ + H++ ++
Sbjct: 93 TTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVS 152
Query: 373 ALCFSPNR---YWLCAAFGPSIKIWDLESKEMVEELRPEIINQT---QTSKTDPPQCLSL 212
+ FSPN + + +K+W+L + +L+ I T T P L
Sbjct: 153 CVRFSPNSSNPIIVSCGWDKLVKVWNLANC----KLKTNHIGHTGYLNTVTVSPDGSLCA 208
Query: 211 AWSTDGQTLFAGYSD 167
+ DGQ + +++
Sbjct: 209 SGGKDGQAMLWDFNE 223
>AK002149-1|BAA92110.1| 330|Homo sapiens protein ( Homo sapiens
cDNA FLJ11287 fis, clone PLACE1009596, weakly similar to
VEGETATIBLE INCOMPATIBILITY PROTEIN HET-E-1. ).
Length = 330
Score = 92.7 bits (220), Expect = 1e-18
Identities = 61/196 (31%), Positives = 100/196 (51%), Gaps = 5/196 (2%)
Frame = -2
Query: 715 SRDKTIKLWNTLA-ECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
S DKT+KLW+ + +C T++ GHS++V C F+P + +I+S +D TVK+W +
Sbjct: 102 SDDKTLKLWDVRSGKCLKTLK--GHSNYVFCCNFNP--PSNLIISGSFDETVKIWEVKTG 157
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL--DHNDIITALC 365
K HS ++ V + GSL SG D +WD G+ L TL D N ++ +
Sbjct: 158 KCLKTLSAHSDPVSAVHFNCSGSLIVSGSYDGLCRIWDAASGQCLKTLVDDDNPPVSFVK 217
Query: 364 FSPN-RYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWS-TDGQ 191
FSPN +Y L A ++K+WD + +T T + + C+ +S T G+
Sbjct: 218 FSPNGKYILTATLDNTLKLWDYSRGRCL---------KTYTGQKNEKYCIFANFSVTGGK 268
Query: 190 TLFAGYSDNTIRVWQV 143
+ +G DN + +W +
Sbjct: 269 WIVSGSEDNLVYIWNL 284
Score = 69.3 bits (162), Expect = 1e-11
Identities = 51/194 (26%), Positives = 92/194 (47%), Gaps = 2/194 (1%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK 536
S D+ I +W + KY GH+ +S V +S + + +VS D+T+K+W + + K
Sbjct: 60 SADRLIIIWGAY-DGKYEKTLYGHNLEISDVAWSSDSSR--LVSASDDKTLKLWDVRSGK 116
Query: 535 LKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALCFS 359
GHS Y+ +P +L SG D +W++ GK L TL H+D ++A+ F+
Sbjct: 117 CLKTLKGHSNYVFCCNFNPPSNLIISGSFDETVKIWEVKTGKCLKTLSAHSDPVSAVHFN 176
Query: 358 -PNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLF 182
+ ++ +IWD S + ++ L + D P + +S +G+ +
Sbjct: 177 CSGSLIVSGSYDGLCRIWDAASGQCLKTLVDD----------DNPPVSFVKFSPNGKYIL 226
Query: 181 AGYSDNTIRVWQVS 140
DNT+++W S
Sbjct: 227 TATLDNTLKLWDYS 240
Score = 67.7 bits (158), Expect = 4e-11
Identities = 45/172 (26%), Positives = 84/172 (48%), Gaps = 2/172 (1%)
Frame = -2
Query: 649 GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGS 470
GH++ VS V+FSPN + S DR + +W + K + GH+ ++ V S D S
Sbjct: 39 GHTEAVSSVKFSPN--GEWLASSSADRLIIIWGAYDGKYEKTLYGHNLEISDVAWSSDSS 96
Query: 469 LCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCFS-PNRYWLCAAFGPSIKIWDLES 296
S D LWD+ GK L TL H++ + F+ P+ + +F ++KIW++++
Sbjct: 97 RLVSASDDKTLKLWDVRSGKCLKTLKGHSNYVFCCNFNPPSNLIISGSFDETVKIWEVKT 156
Query: 295 KEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQVS 140
+ + +T ++ +DP ++ ++ G + +G D R+W +
Sbjct: 157 GKCL---------KTLSAHSDPVS--AVHFNCSGSLIVSGSYDGLCRIWDAA 197
Score = 53.2 bits (122), Expect = 9e-07
Identities = 38/136 (27%), Positives = 67/136 (49%), Gaps = 2/136 (1%)
Frame = -2
Query: 544 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITAL 368
N LK +GH+ +++V SP+G AS D ++W DGK+ TL HN I+ +
Sbjct: 30 NYALKCTLVGHTEAVSSVKFSPNGEWLASSSADRLIIIWGAYDGKYEKTLYGHNLEISDV 89
Query: 367 CFSPNRYWLCAAF-GPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQ 191
+S + L +A ++K+WD+ S + ++ L+ N +PP L
Sbjct: 90 AWSSDSSRLVSASDDKTLKLWDVRSGKCLKTLKGH-SNYVFCCNFNPPSNL--------- 139
Query: 190 TLFAGYSDNTIRVWQV 143
+ +G D T+++W+V
Sbjct: 140 -IISGSFDETVKIWEV 154
Score = 31.9 bits (69), Expect = 2.4
Identities = 26/100 (26%), Positives = 39/100 (39%), Gaps = 3/100 (3%)
Frame = -2
Query: 709 DKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKL 533
D T+KLW+ + C T + + FS IVS D V +W+L ++
Sbjct: 231 DNTLKLWDYSRGRCLKTYTGQKNEKYCIFANFSVT-GGKWIVSGSEDNLVYIWNLQTKEI 289
Query: 532 KINHLGHSGYLNTVTVSPDGSLCASGG--KDMKAMLWDLN 419
GH+ + + P +L AS D LW N
Sbjct: 290 VQKLQGHTDVVISAACHPTENLIASAALENDKTIKLWMSN 329
>CR457279-1|CAG33560.1| 330|Homo sapiens WDR5B protein.
Length = 330
Score = 91.9 bits (218), Expect = 2e-18
Identities = 61/196 (31%), Positives = 99/196 (50%), Gaps = 5/196 (2%)
Frame = -2
Query: 715 SRDKTIKLWNTLA-ECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
S DKT+KLW+ + +C T++ GHS++V C F+P + +I+S +D TVK+W +
Sbjct: 102 SDDKTLKLWDVRSGKCLKTLK--GHSNYVFCCNFNP--PSNLIISGSFDETVKIWEVKTG 157
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL--DHNDIITALC 365
K HS ++ V + GSL SG D +WD G+ L TL D N ++ +
Sbjct: 158 KCLKTLSAHSDPVSAVHFNCSGSLIVSGSYDGLCRIWDAASGQCLKTLVDDDNPPVSFVK 217
Query: 364 FSPN-RYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWS-TDGQ 191
FSPN +Y L A ++K+WD + +T T + C+ +S T G+
Sbjct: 218 FSPNGKYILTATLDNTLKLWDYSRGRCL---------KTYTGHKNEKYCIFANFSVTGGK 268
Query: 190 TLFAGYSDNTIRVWQV 143
+ +G DN + +W +
Sbjct: 269 WIVSGSEDNLVYIWNL 284
Score = 69.3 bits (162), Expect = 1e-11
Identities = 51/194 (26%), Positives = 92/194 (47%), Gaps = 2/194 (1%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK 536
S D+ I +W + KY GH+ +S V +S + + +VS D+T+K+W + + K
Sbjct: 60 SADRLIIIWGAY-DGKYEKTLYGHNLEISDVAWSSDSSR--LVSASDDKTLKLWDVRSGK 116
Query: 535 LKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALCFS 359
GHS Y+ +P +L SG D +W++ GK L TL H+D ++A+ F+
Sbjct: 117 CLKTLKGHSNYVFCCNFNPPSNLIISGSFDETVKIWEVKTGKCLKTLSAHSDPVSAVHFN 176
Query: 358 -PNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLF 182
+ ++ +IWD S + ++ L + D P + +S +G+ +
Sbjct: 177 CSGSLIVSGSYDGLCRIWDAASGQCLKTLVDD----------DNPPVSFVKFSPNGKYIL 226
Query: 181 AGYSDNTIRVWQVS 140
DNT+++W S
Sbjct: 227 TATLDNTLKLWDYS 240
Score = 67.7 bits (158), Expect = 4e-11
Identities = 45/172 (26%), Positives = 84/172 (48%), Gaps = 2/172 (1%)
Frame = -2
Query: 649 GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGS 470
GH++ VS V+FSPN + S DR + +W + K + GH+ ++ V S D S
Sbjct: 39 GHTEAVSSVKFSPN--GEWLASSSADRLIIIWGAYDGKYEKTLYGHNLEISDVAWSSDSS 96
Query: 469 LCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCFS-PNRYWLCAAFGPSIKIWDLES 296
S D LWD+ GK L TL H++ + F+ P+ + +F ++KIW++++
Sbjct: 97 RLVSASDDKTLKLWDVRSGKCLKTLKGHSNYVFCCNFNPPSNLIISGSFDETVKIWEVKT 156
Query: 295 KEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQVS 140
+ + +T ++ +DP ++ ++ G + +G D R+W +
Sbjct: 157 GKCL---------KTLSAHSDPVS--AVHFNCSGSLIVSGSYDGLCRIWDAA 197
Score = 53.2 bits (122), Expect = 9e-07
Identities = 38/136 (27%), Positives = 67/136 (49%), Gaps = 2/136 (1%)
Frame = -2
Query: 544 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITAL 368
N LK +GH+ +++V SP+G AS D ++W DGK+ TL HN I+ +
Sbjct: 30 NYALKCTLVGHTEAVSSVKFSPNGEWLASSSADRLIIIWGAYDGKYEKTLYGHNLEISDV 89
Query: 367 CFSPNRYWLCAAF-GPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQ 191
+S + L +A ++K+WD+ S + ++ L+ N +PP L
Sbjct: 90 AWSSDSSRLVSASDDKTLKLWDVRSGKCLKTLKGH-SNYVFCCNFNPPSNL--------- 139
Query: 190 TLFAGYSDNTIRVWQV 143
+ +G D T+++W+V
Sbjct: 140 -IISGSFDETVKIWEV 154
Score = 31.9 bits (69), Expect = 2.4
Identities = 29/102 (28%), Positives = 42/102 (41%), Gaps = 5/102 (4%)
Frame = -2
Query: 709 DKTIKLWN-TLAECKYTIQDDGHSDWVSCV--RFSPNHANPIIVSCGWDRTVKVWHLTNC 539
D T+KLW+ + C T GH + C+ FS IVS D V +W+L
Sbjct: 231 DNTLKLWDYSRGRCLKTYT--GHKNEKYCIFANFSVT-GGKWIVSGSEDNLVYIWNLQTK 287
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGG--KDMKAMLWDLN 419
++ GH+ + + P +L AS D LW N
Sbjct: 288 EIVQKLQGHTDVVISAACHPTENLIASAALENDKTIKLWMSN 329
>BC043494-1|AAH43494.1| 330|Homo sapiens WD repeat domain 5B
protein.
Length = 330
Score = 91.9 bits (218), Expect = 2e-18
Identities = 61/196 (31%), Positives = 99/196 (50%), Gaps = 5/196 (2%)
Frame = -2
Query: 715 SRDKTIKLWNTLA-ECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
S DKT+KLW+ + +C T++ GHS++V C F+P + +I+S +D TVK+W +
Sbjct: 102 SDDKTLKLWDVRSGKCLKTLK--GHSNYVFCCNFNP--PSNLIISGSFDETVKIWEVKTG 157
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL--DHNDIITALC 365
K HS ++ V + GSL SG D +WD G+ L TL D N ++ +
Sbjct: 158 KCLKTLSAHSDPVSAVHFNCSGSLIVSGSYDGLCRIWDAASGQCLKTLVDDDNPPVSFVK 217
Query: 364 FSPN-RYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWS-TDGQ 191
FSPN +Y L A ++K+WD + +T T + C+ +S T G+
Sbjct: 218 FSPNGKYILTATLDNTLKLWDYSRGRCL---------KTYTGHKNEKYCIFANFSVTGGK 268
Query: 190 TLFAGYSDNTIRVWQV 143
+ +G DN + +W +
Sbjct: 269 WIVSGSEDNLVYIWNL 284
Score = 69.3 bits (162), Expect = 1e-11
Identities = 51/194 (26%), Positives = 92/194 (47%), Gaps = 2/194 (1%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK 536
S D+ I +W + KY GH+ +S V +S + + +VS D+T+K+W + + K
Sbjct: 60 SADRLIIIWGAY-DGKYEKTLYGHNLEISDVAWSSDSSR--LVSASDDKTLKLWDVRSGK 116
Query: 535 LKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALCFS 359
GHS Y+ +P +L SG D +W++ GK L TL H+D ++A+ F+
Sbjct: 117 CLKTLKGHSNYVFCCNFNPPSNLIISGSFDETVKIWEVKTGKCLKTLSAHSDPVSAVHFN 176
Query: 358 -PNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLF 182
+ ++ +IWD S + ++ L + D P + +S +G+ +
Sbjct: 177 CSGSLIVSGSYDGLCRIWDAASGQCLKTLVDD----------DNPPVSFVKFSPNGKYIL 226
Query: 181 AGYSDNTIRVWQVS 140
DNT+++W S
Sbjct: 227 TATLDNTLKLWDYS 240
Score = 67.7 bits (158), Expect = 4e-11
Identities = 45/172 (26%), Positives = 84/172 (48%), Gaps = 2/172 (1%)
Frame = -2
Query: 649 GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGS 470
GH++ VS V+FSPN + S DR + +W + K + GH+ ++ V S D S
Sbjct: 39 GHTEAVSSVKFSPN--GEWLASSSADRLIIIWGAYDGKYEKTLYGHNLEISDVAWSSDSS 96
Query: 469 LCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCFS-PNRYWLCAAFGPSIKIWDLES 296
S D LWD+ GK L TL H++ + F+ P+ + +F ++KIW++++
Sbjct: 97 RLVSASDDKTLKLWDVRSGKCLKTLKGHSNYVFCCNFNPPSNLIISGSFDETVKIWEVKT 156
Query: 295 KEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQVS 140
+ + +T ++ +DP ++ ++ G + +G D R+W +
Sbjct: 157 GKCL---------KTLSAHSDPVS--AVHFNCSGSLIVSGSYDGLCRIWDAA 197
Score = 53.2 bits (122), Expect = 9e-07
Identities = 38/136 (27%), Positives = 67/136 (49%), Gaps = 2/136 (1%)
Frame = -2
Query: 544 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITAL 368
N LK +GH+ +++V SP+G AS D ++W DGK+ TL HN I+ +
Sbjct: 30 NYALKCTLVGHTEAVSSVKFSPNGEWLASSSADRLIIIWGAYDGKYEKTLYGHNLEISDV 89
Query: 367 CFSPNRYWLCAAF-GPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQ 191
+S + L +A ++K+WD+ S + ++ L+ N +PP L
Sbjct: 90 AWSSDSSRLVSASDDKTLKLWDVRSGKCLKTLKGH-SNYVFCCNFNPPSNL--------- 139
Query: 190 TLFAGYSDNTIRVWQV 143
+ +G D T+++W+V
Sbjct: 140 -IISGSFDETVKIWEV 154
Score = 31.9 bits (69), Expect = 2.4
Identities = 29/102 (28%), Positives = 42/102 (41%), Gaps = 5/102 (4%)
Frame = -2
Query: 709 DKTIKLWN-TLAECKYTIQDDGHSDWVSCV--RFSPNHANPIIVSCGWDRTVKVWHLTNC 539
D T+KLW+ + C T GH + C+ FS IVS D V +W+L
Sbjct: 231 DNTLKLWDYSRGRCLKTYT--GHKNEKYCIFANFSVT-GGKWIVSGSEDNLVYIWNLQTK 287
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGG--KDMKAMLWDLN 419
++ GH+ + + P +L AS D LW N
Sbjct: 288 EIVQKLQGHTDVVISAACHPTENLIASAALENDKTIKLWMSN 329
>BX649632-1|CAI18774.1| 334|Homo sapiens WD repeat domain 5
protein.
Length = 334
Score = 89.8 bits (213), Expect = 8e-18
Identities = 59/196 (30%), Positives = 100/196 (51%), Gaps = 5/196 (2%)
Frame = -2
Query: 715 SRDKTIKLWNTLA-ECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
S DKT+K+W+ + +C T++ GHS++V C F+P + +IVS +D +V++W +
Sbjct: 106 SDDKTLKIWDVSSGKCLKTLK--GHSNYVFCCNFNPQ--SNLIVSGSFDESVRIWDVKTG 161
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL--DHNDIITALC 365
K HS ++ V + DGSL S D +WD G+ L TL D N ++ +
Sbjct: 162 KCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVK 221
Query: 364 FSPN-RYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWS-TDGQ 191
FSPN +Y L A ++K+WD + ++ T T + C+ +S T G+
Sbjct: 222 FSPNGKYILAATLDNTLKLWDYSKGKCLK---------TYTGHKNEKYCIFANFSVTGGK 272
Query: 190 TLFAGYSDNTIRVWQV 143
+ +G DN + +W +
Sbjct: 273 WIVSGSEDNLVYIWNL 288
Score = 80.2 bits (189), Expect = 7e-15
Identities = 54/194 (27%), Positives = 96/194 (49%), Gaps = 2/194 (1%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK 536
S DK IK+W + K+ GH +S V +S + + ++VS D+T+K+W +++ K
Sbjct: 64 SADKLIKIWGAY-DGKFEKTISGHKLGISDVAWSSD--SNLLVSASDDKTLKIWDVSSGK 120
Query: 535 LKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALCFS 359
GHS Y+ +P +L SG D +WD+ GK L TL H+D ++A+ F+
Sbjct: 121 CLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFN 180
Query: 358 -PNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLF 182
+ +++ +IWD S + ++ L + D P + +S +G+ +
Sbjct: 181 RDGSLIVSSSYDGLCRIWDTASGQCLKTLIDD----------DNPPVSFVKFSPNGKYIL 230
Query: 181 AGYSDNTIRVWQVS 140
A DNT+++W S
Sbjct: 231 AATLDNTLKLWDYS 244
Score = 69.3 bits (162), Expect = 1e-11
Identities = 47/179 (26%), Positives = 88/179 (49%), Gaps = 2/179 (1%)
Frame = -2
Query: 670 KYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTV 491
K+T+ GH+ VS V+FSPN + S D+ +K+W + K + GH ++ V
Sbjct: 38 KFTLA--GHTKAVSSVKFSPN--GEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDV 93
Query: 490 TVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCFSP-NRYWLCAAFGPSI 317
S D +L S D +WD++ GK L TL H++ + F+P + + +F S+
Sbjct: 94 AWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESV 153
Query: 316 KIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQVS 140
+IWD+++ + + +T + +DP ++ ++ DG + + D R+W +
Sbjct: 154 RIWDVKTGKCL---------KTLPAHSDPVS--AVHFNRDGSLIVSSSYDGLCRIWDTA 201
Score = 54.0 bits (124), Expect = 5e-07
Identities = 42/156 (26%), Positives = 76/156 (48%), Gaps = 7/156 (4%)
Frame = -2
Query: 718 GSRDKTIKLWNT-LAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
GS D+++++W+ +C T+ HSD VS V F N +IVS +D ++W +
Sbjct: 147 GSFDESVRIWDVKTGKCLKTLP--AHSDPVSAVHF--NRDGSLIVSSSYDGLCRIWDTAS 202
Query: 541 CK-LKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHT-LDHND----I 380
+ LK + ++ V SP+G + D LWD + GK L T H + I
Sbjct: 203 GQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCI 262
Query: 379 ITALCFSPNRYWLCAAFGPSIKIWDLESKEMVEELR 272
+ ++ + + + IW+L++KE+V++L+
Sbjct: 263 FANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQ 298
Score = 44.4 bits (100), Expect = 4e-04
Identities = 28/93 (30%), Positives = 47/93 (50%), Gaps = 2/93 (2%)
Frame = -2
Query: 544 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITAL 368
N LK GH+ +++V SP+G AS D +W DGK T+ H I+ +
Sbjct: 34 NYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDV 93
Query: 367 CFSPNRYWLCAAF-GPSIKIWDLESKEMVEELR 272
+S + L +A ++KIWD+ S + ++ L+
Sbjct: 94 AWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLK 126
Score = 31.1 bits (67), Expect = 4.1
Identities = 27/99 (27%), Positives = 42/99 (42%), Gaps = 5/99 (5%)
Frame = -2
Query: 709 DKTIKLWN-TLAECKYTIQDDGHSDWVSCV--RFSPNHANPIIVSCGWDRTVKVWHLTNC 539
D T+KLW+ + +C T GH + C+ FS IVS D V +W+L
Sbjct: 235 DNTLKLWDYSKGKCLKTYT--GHKNEKYCIFANFSVT-GGKWIVSGSEDNLVYIWNLQTK 291
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGG--KDMKAMLW 428
++ GH+ + + P ++ AS D LW
Sbjct: 292 EIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLW 330
>BC001635-1|AAH01635.1| 334|Homo sapiens WD repeat domain 5
protein.
Length = 334
Score = 89.8 bits (213), Expect = 8e-18
Identities = 59/196 (30%), Positives = 100/196 (51%), Gaps = 5/196 (2%)
Frame = -2
Query: 715 SRDKTIKLWNTLA-ECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
S DKT+K+W+ + +C T++ GHS++V C F+P + +IVS +D +V++W +
Sbjct: 106 SDDKTLKIWDVSSGKCLKTLK--GHSNYVFCCNFNPQ--SNLIVSGSFDESVRIWDVKTG 161
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL--DHNDIITALC 365
K HS ++ V + DGSL S D +WD G+ L TL D N ++ +
Sbjct: 162 KCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVK 221
Query: 364 FSPN-RYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWS-TDGQ 191
FSPN +Y L A ++K+WD + ++ T T + C+ +S T G+
Sbjct: 222 FSPNGKYILAATLDNTLKLWDYSKGKCLK---------TYTGHKNEKYCIFANFSVTGGK 272
Query: 190 TLFAGYSDNTIRVWQV 143
+ +G DN + +W +
Sbjct: 273 WIVSGSEDNLVYIWNL 288
Score = 80.2 bits (189), Expect = 7e-15
Identities = 54/194 (27%), Positives = 96/194 (49%), Gaps = 2/194 (1%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK 536
S DK IK+W + K+ GH +S V +S + + ++VS D+T+K+W +++ K
Sbjct: 64 SADKLIKIWGAY-DGKFEKTISGHKLGISDVAWSSD--SNLLVSASDDKTLKIWDVSSGK 120
Query: 535 LKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALCFS 359
GHS Y+ +P +L SG D +WD+ GK L TL H+D ++A+ F+
Sbjct: 121 CLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFN 180
Query: 358 -PNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLF 182
+ +++ +IWD S + ++ L + D P + +S +G+ +
Sbjct: 181 RDGSLIVSSSYDGLCRIWDTASGQCLKTLIDD----------DNPPVSFVKFSPNGKYIL 230
Query: 181 AGYSDNTIRVWQVS 140
A DNT+++W S
Sbjct: 231 AATLDNTLKLWDYS 244
Score = 69.3 bits (162), Expect = 1e-11
Identities = 47/179 (26%), Positives = 88/179 (49%), Gaps = 2/179 (1%)
Frame = -2
Query: 670 KYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTV 491
K+T+ GH+ VS V+FSPN + S D+ +K+W + K + GH ++ V
Sbjct: 38 KFTLA--GHTKAVSSVKFSPN--GEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDV 93
Query: 490 TVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCFSP-NRYWLCAAFGPSI 317
S D +L S D +WD++ GK L TL H++ + F+P + + +F S+
Sbjct: 94 AWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESV 153
Query: 316 KIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQVS 140
+IWD+++ + + +T + +DP ++ ++ DG + + D R+W +
Sbjct: 154 RIWDVKTGKCL---------KTLPAHSDPVS--AVHFNRDGSLIVSSSYDGLCRIWDTA 201
Score = 54.0 bits (124), Expect = 5e-07
Identities = 42/156 (26%), Positives = 76/156 (48%), Gaps = 7/156 (4%)
Frame = -2
Query: 718 GSRDKTIKLWNT-LAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
GS D+++++W+ +C T+ HSD VS V F N +IVS +D ++W +
Sbjct: 147 GSFDESVRIWDVKTGKCLKTLP--AHSDPVSAVHF--NRDGSLIVSSSYDGLCRIWDTAS 202
Query: 541 CK-LKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHT-LDHND----I 380
+ LK + ++ V SP+G + D LWD + GK L T H + I
Sbjct: 203 GQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCI 262
Query: 379 ITALCFSPNRYWLCAAFGPSIKIWDLESKEMVEELR 272
+ ++ + + + IW+L++KE+V++L+
Sbjct: 263 FANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQ 298
Score = 44.4 bits (100), Expect = 4e-04
Identities = 28/93 (30%), Positives = 47/93 (50%), Gaps = 2/93 (2%)
Frame = -2
Query: 544 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITAL 368
N LK GH+ +++V SP+G AS D +W DGK T+ H I+ +
Sbjct: 34 NYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDV 93
Query: 367 CFSPNRYWLCAAF-GPSIKIWDLESKEMVEELR 272
+S + L +A ++KIWD+ S + ++ L+
Sbjct: 94 AWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLK 126
Score = 31.1 bits (67), Expect = 4.1
Identities = 27/99 (27%), Positives = 42/99 (42%), Gaps = 5/99 (5%)
Frame = -2
Query: 709 DKTIKLWN-TLAECKYTIQDDGHSDWVSCV--RFSPNHANPIIVSCGWDRTVKVWHLTNC 539
D T+KLW+ + +C T GH + C+ FS IVS D V +W+L
Sbjct: 235 DNTLKLWDYSKGKCLKTYT--GHKNEKYCIFANFSVT-GGKWIVSGSEDNLVYIWNLQTK 291
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGG--KDMKAMLW 428
++ GH+ + + P ++ AS D LW
Sbjct: 292 EIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLW 330
>AK000552-1|BAA91248.1| 334|Homo sapiens protein ( Homo sapiens
cDNA FLJ20545 fis, clone KAT11476. ).
Length = 334
Score = 89.8 bits (213), Expect = 8e-18
Identities = 59/196 (30%), Positives = 100/196 (51%), Gaps = 5/196 (2%)
Frame = -2
Query: 715 SRDKTIKLWNTLA-ECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
S DKT+K+W+ + +C T++ GHS++V C F+P + +IVS +D +V++W +
Sbjct: 106 SDDKTLKIWDVSSGKCLKTLK--GHSNYVFCCNFNPQ--SNLIVSGSFDESVRIWDVKTG 161
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL--DHNDIITALC 365
K HS ++ V + DGSL S D +WD G+ L TL D N ++ +
Sbjct: 162 KCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVK 221
Query: 364 FSPN-RYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWS-TDGQ 191
FSPN +Y L A ++K+WD + ++ T T + C+ +S T G+
Sbjct: 222 FSPNGKYILAATLDNTLKLWDYSKGKCLK---------TYTGHKNEKYCIFANFSVTGGK 272
Query: 190 TLFAGYSDNTIRVWQV 143
+ +G DN + +W +
Sbjct: 273 WIVSGSEDNLVYIWNL 288
Score = 80.2 bits (189), Expect = 7e-15
Identities = 54/194 (27%), Positives = 96/194 (49%), Gaps = 2/194 (1%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK 536
S DK IK+W + K+ GH +S V +S + + ++VS D+T+K+W +++ K
Sbjct: 64 SADKLIKIWGAY-DGKFEKTISGHKLGISDVAWSSD--SNLLVSASDDKTLKIWDVSSGK 120
Query: 535 LKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALCFS 359
GHS Y+ +P +L SG D +WD+ GK L TL H+D ++A+ F+
Sbjct: 121 CLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFN 180
Query: 358 -PNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLF 182
+ +++ +IWD S + ++ L + D P + +S +G+ +
Sbjct: 181 RDGSLIVSSSYDGLCRIWDTASGQCLKTLIDD----------DNPPVSFVKFSPNGKYIL 230
Query: 181 AGYSDNTIRVWQVS 140
A DNT+++W S
Sbjct: 231 AATLDNTLKLWDYS 244
Score = 69.3 bits (162), Expect = 1e-11
Identities = 47/179 (26%), Positives = 88/179 (49%), Gaps = 2/179 (1%)
Frame = -2
Query: 670 KYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTV 491
K+T+ GH+ VS V+FSPN + S D+ +K+W + K + GH ++ V
Sbjct: 38 KFTLA--GHTKAVSSVKFSPN--GEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDV 93
Query: 490 TVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCFSP-NRYWLCAAFGPSI 317
S D +L S D +WD++ GK L TL H++ + F+P + + +F S+
Sbjct: 94 AWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESV 153
Query: 316 KIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQVS 140
+IWD+++ + + +T + +DP ++ ++ DG + + D R+W +
Sbjct: 154 RIWDVKTGKCL---------KTLPAHSDPVS--AVHFNRDGSLIVSSSYDGLCRIWDTA 201
Score = 54.0 bits (124), Expect = 5e-07
Identities = 42/156 (26%), Positives = 76/156 (48%), Gaps = 7/156 (4%)
Frame = -2
Query: 718 GSRDKTIKLWNT-LAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
GS D+++++W+ +C T+ HSD VS V F N +IVS +D ++W +
Sbjct: 147 GSFDESVRIWDVKTGKCLKTLP--AHSDPVSAVHF--NRDGSLIVSSSYDGLCRIWDTAS 202
Query: 541 CK-LKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHT-LDHND----I 380
+ LK + ++ V SP+G + D LWD + GK L T H + I
Sbjct: 203 GQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCI 262
Query: 379 ITALCFSPNRYWLCAAFGPSIKIWDLESKEMVEELR 272
+ ++ + + + IW+L++KE+V++L+
Sbjct: 263 FANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQ 298
Score = 44.4 bits (100), Expect = 4e-04
Identities = 28/93 (30%), Positives = 47/93 (50%), Gaps = 2/93 (2%)
Frame = -2
Query: 544 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITAL 368
N LK GH+ +++V SP+G AS D +W DGK T+ H I+ +
Sbjct: 34 NYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDV 93
Query: 367 CFSPNRYWLCAAF-GPSIKIWDLESKEMVEELR 272
+S + L +A ++KIWD+ S + ++ L+
Sbjct: 94 AWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLK 126
Score = 31.1 bits (67), Expect = 4.1
Identities = 27/99 (27%), Positives = 42/99 (42%), Gaps = 5/99 (5%)
Frame = -2
Query: 709 DKTIKLWN-TLAECKYTIQDDGHSDWVSCV--RFSPNHANPIIVSCGWDRTVKVWHLTNC 539
D T+KLW+ + +C T GH + C+ FS IVS D V +W+L
Sbjct: 235 DNTLKLWDYSKGKCLKTYT--GHKNEKYCIFANFSVT-GGKWIVSGSEDNLVYIWNLQTK 291
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGG--KDMKAMLW 428
++ GH+ + + P ++ AS D LW
Sbjct: 292 EIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLW 330
>AJ011376-1|CAB66159.1| 362|Homo sapiens hypothetical protein
protein.
Length = 362
Score = 89.8 bits (213), Expect = 8e-18
Identities = 59/196 (30%), Positives = 100/196 (51%), Gaps = 5/196 (2%)
Frame = -2
Query: 715 SRDKTIKLWNTLA-ECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
S DKT+K+W+ + +C T++ GHS++V C F+P + +IVS +D +V++W +
Sbjct: 134 SDDKTLKIWDVSSGKCLKTLK--GHSNYVFCCNFNPQ--SNLIVSGSFDESVRIWDVKTG 189
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL--DHNDIITALC 365
K HS ++ V + DGSL S D +WD G+ L TL D N ++ +
Sbjct: 190 KCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVK 249
Query: 364 FSPN-RYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWS-TDGQ 191
FSPN +Y L A ++K+WD + ++ T T + C+ +S T G+
Sbjct: 250 FSPNGKYILAATLDNTLKLWDYSKGKCLK---------TYTGHKNEKYCIFANFSVTGGK 300
Query: 190 TLFAGYSDNTIRVWQV 143
+ +G DN + +W +
Sbjct: 301 WIVSGSEDNLVYIWNL 316
Score = 80.2 bits (189), Expect = 7e-15
Identities = 54/194 (27%), Positives = 96/194 (49%), Gaps = 2/194 (1%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK 536
S DK IK+W + K+ GH +S V +S + + ++VS D+T+K+W +++ K
Sbjct: 92 SADKLIKIWGAY-DGKFEKTISGHKLGISDVAWSSD--SNLLVSASDDKTLKIWDVSSGK 148
Query: 535 LKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALCFS 359
GHS Y+ +P +L SG D +WD+ GK L TL H+D ++A+ F+
Sbjct: 149 CLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFN 208
Query: 358 -PNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLF 182
+ +++ +IWD S + ++ L + D P + +S +G+ +
Sbjct: 209 RDGSLIVSSSYDGLCRIWDTASGQCLKTLIDD----------DNPPVSFVKFSPNGKYIL 258
Query: 181 AGYSDNTIRVWQVS 140
A DNT+++W S
Sbjct: 259 AATLDNTLKLWDYS 272
Score = 69.3 bits (162), Expect = 1e-11
Identities = 47/179 (26%), Positives = 88/179 (49%), Gaps = 2/179 (1%)
Frame = -2
Query: 670 KYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTV 491
K+T+ GH+ VS V+FSPN + S D+ +K+W + K + GH ++ V
Sbjct: 66 KFTLA--GHTKAVSSVKFSPN--GEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDV 121
Query: 490 TVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCFSP-NRYWLCAAFGPSI 317
S D +L S D +WD++ GK L TL H++ + F+P + + +F S+
Sbjct: 122 AWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESV 181
Query: 316 KIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQVS 140
+IWD+++ + + +T + +DP ++ ++ DG + + D R+W +
Sbjct: 182 RIWDVKTGKCL---------KTLPAHSDPVS--AVHFNRDGSLIVSSSYDGLCRIWDTA 229
Score = 54.0 bits (124), Expect = 5e-07
Identities = 42/156 (26%), Positives = 76/156 (48%), Gaps = 7/156 (4%)
Frame = -2
Query: 718 GSRDKTIKLWNT-LAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
GS D+++++W+ +C T+ HSD VS V F N +IVS +D ++W +
Sbjct: 175 GSFDESVRIWDVKTGKCLKTLP--AHSDPVSAVHF--NRDGSLIVSSSYDGLCRIWDTAS 230
Query: 541 CK-LKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHT-LDHND----I 380
+ LK + ++ V SP+G + D LWD + GK L T H + I
Sbjct: 231 GQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCI 290
Query: 379 ITALCFSPNRYWLCAAFGPSIKIWDLESKEMVEELR 272
+ ++ + + + IW+L++KE+V++L+
Sbjct: 291 FANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQ 326
Score = 44.4 bits (100), Expect = 4e-04
Identities = 28/93 (30%), Positives = 47/93 (50%), Gaps = 2/93 (2%)
Frame = -2
Query: 544 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITAL 368
N LK GH+ +++V SP+G AS D +W DGK T+ H I+ +
Sbjct: 62 NYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDV 121
Query: 367 CFSPNRYWLCAAF-GPSIKIWDLESKEMVEELR 272
+S + L +A ++KIWD+ S + ++ L+
Sbjct: 122 AWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLK 154
Score = 31.1 bits (67), Expect = 4.1
Identities = 27/99 (27%), Positives = 42/99 (42%), Gaps = 5/99 (5%)
Frame = -2
Query: 709 DKTIKLWN-TLAECKYTIQDDGHSDWVSCV--RFSPNHANPIIVSCGWDRTVKVWHLTNC 539
D T+KLW+ + +C T GH + C+ FS IVS D V +W+L
Sbjct: 263 DNTLKLWDYSKGKCLKTYT--GHKNEKYCIFANFSVT-GGKWIVSGSEDNLVYIWNLQTK 319
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGG--KDMKAMLW 428
++ GH+ + + P ++ AS D LW
Sbjct: 320 EIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLW 358
>EF011619-1|ABK41109.1| 478|Homo sapiens CDW9/WDR51B protein.
Length = 478
Score = 89.0 bits (211), Expect = 1e-17
Identities = 55/194 (28%), Positives = 96/194 (49%), Gaps = 2/194 (1%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK 536
S DK+IK+W+ + ++ H+ WV C +FSP+ +IVSC D+T+K+W TN +
Sbjct: 121 SEDKSIKVWSMYRQ-RFLYSLYRHTHWVRCAKFSPD--GRLIVSCSEDKTIKIWDTTNKQ 177
Query: 535 LKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHL-HTLDHNDIITALCFS 359
N G+ N V +P G+ AS G D +WD+ K L H H+ + + F
Sbjct: 178 CVNNFSDSVGFANFVDFNPSGTCIASAGSDQTVKVWDVRVNKLLQHYQVHSGGVNCISFH 237
Query: 358 PN-RYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLF 182
P+ Y + A+ ++KI DL ++ L+ T P ++++S G+
Sbjct: 238 PSGNYLITASSDGTLKILDLLEGRLIYTLQ---------GHTGP--VFTVSFSKGGELFA 286
Query: 181 AGYSDNTIRVWQVS 140
+G +D + +W+ +
Sbjct: 287 SGGADTQVLLWRTN 300
Score = 54.8 bits (126), Expect = 3e-07
Identities = 41/172 (23%), Positives = 74/172 (43%), Gaps = 2/172 (1%)
Frame = -2
Query: 649 GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGS 470
GH ++ + SPN + + WD + +W+ ++GH + +V SP G+
Sbjct: 16 GHKAAITSLDLSPNGKQ--LATASWDTFLMLWNFKPHARAYRYVGHKDVVTSVQFSPHGN 73
Query: 469 LCASGGKDMKAMLWDLND-GKHLHTLDHNDIITALCFSPNRYWLC-AAFGPSIKIWDLES 296
L AS +D LW + GK H + ++ FS + +L A+ SIK+W +
Sbjct: 74 LLASASRDRTVRLWIPDKRGKFSEFKAHTAPVRSVDFSADGQFLATASEDKSIKVWSMYR 133
Query: 295 KEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQVS 140
+ + L T +C +S DG+ + + D TI++W +
Sbjct: 134 QRFLYSL---------YRHTHWVRCAK--FSPDGRLIVSCSEDKTIKIWDTT 174
Score = 54.0 bits (124), Expect = 5e-07
Identities = 33/147 (22%), Positives = 71/147 (48%), Gaps = 2/147 (1%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK 536
SRD+T++LW K++ + H+ V V FS + + + D+++KVW + +
Sbjct: 79 SRDRTVRLWIPDKRGKFS-EFKAHTAPVRSVDFSAD--GQFLATASEDKSIKVWSMYRQR 135
Query: 535 LKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCFS 359
+ H+ ++ SPDG L S +D +WD + + ++ D + F+
Sbjct: 136 FLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVDFN 195
Query: 358 PNRYWLCAA-FGPSIKIWDLESKEMVE 281
P+ + +A ++K+WD+ ++++
Sbjct: 196 PSGTCIASAGSDQTVKVWDVRVNKLLQ 222
>BC026080-1|AAH26080.1| 478|Homo sapiens WD repeat domain 51B
protein.
Length = 478
Score = 89.0 bits (211), Expect = 1e-17
Identities = 55/194 (28%), Positives = 96/194 (49%), Gaps = 2/194 (1%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK 536
S DK+IK+W+ + ++ H+ WV C +FSP+ +IVSC D+T+K+W TN +
Sbjct: 121 SEDKSIKVWSMYRQ-RFLYSLYRHTHWVRCAKFSPD--GRLIVSCSEDKTIKIWDTTNKQ 177
Query: 535 LKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHL-HTLDHNDIITALCFS 359
N G+ N V +P G+ AS G D +WD+ K L H H+ + + F
Sbjct: 178 CVNNFSDSVGFANFVDFNPSGTCIASAGSDQTVKVWDVRVNKLLQHYQVHSGGVNCISFH 237
Query: 358 PN-RYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLF 182
P+ Y + A+ ++KI DL ++ L+ T P ++++S G+
Sbjct: 238 PSGNYLITASSDGTLKILDLLEGRLIYTLQ---------GHTGP--VFTVSFSKGGELFA 286
Query: 181 AGYSDNTIRVWQVS 140
+G +D + +W+ +
Sbjct: 287 SGGADTQVLLWRTN 300
Score = 54.8 bits (126), Expect = 3e-07
Identities = 41/172 (23%), Positives = 74/172 (43%), Gaps = 2/172 (1%)
Frame = -2
Query: 649 GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGS 470
GH ++ + SPN + + WD + +W+ ++GH + +V SP G+
Sbjct: 16 GHKAAITSLDLSPNGKQ--LATASWDTFLMLWNFKPHARAYRYVGHKDVVTSVQFSPHGN 73
Query: 469 LCASGGKDMKAMLWDLND-GKHLHTLDHNDIITALCFSPNRYWLC-AAFGPSIKIWDLES 296
L AS +D LW + GK H + ++ FS + +L A+ SIK+W +
Sbjct: 74 LLASASRDRTVRLWIPDKRGKFSEFKAHTAPVRSVDFSADGQFLATASEDKSIKVWSMYR 133
Query: 295 KEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQVS 140
+ + L T +C +S DG+ + + D TI++W +
Sbjct: 134 QRFLYSL---------YRHTHWVRCAK--FSPDGRLIVSCSEDKTIKIWDTT 174
Score = 54.0 bits (124), Expect = 5e-07
Identities = 33/147 (22%), Positives = 71/147 (48%), Gaps = 2/147 (1%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK 536
SRD+T++LW K++ + H+ V V FS + + + D+++KVW + +
Sbjct: 79 SRDRTVRLWIPDKRGKFS-EFKAHTAPVRSVDFSAD--GQFLATASEDKSIKVWSMYRQR 135
Query: 535 LKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCFS 359
+ H+ ++ SPDG L S +D +WD + + ++ D + F+
Sbjct: 136 FLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVDFN 195
Query: 358 PNRYWLCAA-FGPSIKIWDLESKEMVE 281
P+ + +A ++K+WD+ ++++
Sbjct: 196 PSGTCIASAGSDQTVKVWDVRVNKLLQ 222
>AK074772-1|BAC11198.1| 478|Homo sapiens protein ( Homo sapiens
cDNA FLJ90291 fis, clone NT2RP1001031, weakly similar to
VEGETATIBLE INCOMPATIBILITY PROTEIN HET-E-1. ).
Length = 478
Score = 89.0 bits (211), Expect = 1e-17
Identities = 55/194 (28%), Positives = 96/194 (49%), Gaps = 2/194 (1%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK 536
S DK+IK+W+ + ++ H+ WV C +FSP+ +IVSC D+T+K+W TN +
Sbjct: 121 SEDKSIKVWSMYRQ-RFLYSLYRHTHWVRCAKFSPD--GRLIVSCSEDKTIKIWDTTNKQ 177
Query: 535 LKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHL-HTLDHNDIITALCFS 359
N G+ N V +P G+ AS G D +WD+ K L H H+ + + F
Sbjct: 178 CVNNFSDSVGFANFVDFNPSGTCIASAGSDQTVKVWDVRVNKLLQHYQVHSGGVNCISFH 237
Query: 358 PN-RYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLF 182
P+ Y + A+ ++KI DL ++ L+ T P ++++S G+
Sbjct: 238 PSGNYLITASSDGTLKILDLLEGRLIYTLQ---------GHTGP--VFTVSFSKGGELFA 286
Query: 181 AGYSDNTIRVWQVS 140
+G +D + +W+ +
Sbjct: 287 SGGADTQVLLWRTN 300
Score = 54.8 bits (126), Expect = 3e-07
Identities = 41/172 (23%), Positives = 74/172 (43%), Gaps = 2/172 (1%)
Frame = -2
Query: 649 GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGS 470
GH ++ + SPN + + WD + +W+ ++GH + +V SP G+
Sbjct: 16 GHKAAITSLDLSPNGKQ--LATASWDTFLMLWNFKPHARAYRYVGHKDVVTSVQFSPHGN 73
Query: 469 LCASGGKDMKAMLWDLND-GKHLHTLDHNDIITALCFSPNRYWLC-AAFGPSIKIWDLES 296
L AS +D LW + GK H + ++ FS + +L A+ SIK+W +
Sbjct: 74 LLASASRDRTVRLWIPDKRGKFSEFKAHTAPVRSVDFSADGQFLATASEDKSIKVWSMYR 133
Query: 295 KEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQVS 140
+ + L T +C +S DG+ + + D TI++W +
Sbjct: 134 QRFLYSL---------YRHTHWVRCAK--FSPDGRLIVSCSEDKTIKIWDTT 174
Score = 54.0 bits (124), Expect = 5e-07
Identities = 33/147 (22%), Positives = 71/147 (48%), Gaps = 2/147 (1%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK 536
SRD+T++LW K++ + H+ V V FS + + + D+++KVW + +
Sbjct: 79 SRDRTVRLWIPDKRGKFS-EFKAHTAPVRSVDFSAD--GQFLATASEDKSIKVWSMYRQR 135
Query: 535 LKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCFS 359
+ H+ ++ SPDG L S +D +WD + + ++ D + F+
Sbjct: 136 FLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVDFN 195
Query: 358 PNRYWLCAA-FGPSIKIWDLESKEMVE 281
P+ + +A ++K+WD+ ++++
Sbjct: 196 PSGTCIASAGSDQTVKVWDVRVNKLLQ 222
>BC119693-1|AAI19694.1| 441|Homo sapiens WDR51A protein protein.
Length = 441
Score = 83.4 bits (197), Expect = 7e-16
Identities = 56/192 (29%), Positives = 94/192 (48%), Gaps = 2/192 (1%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK 536
S DKT+K+W T + K+ H +WV C +FSP+ +IVS D+TVK+W ++ +
Sbjct: 156 SDDKTVKVWATHRQ-KFLFSLSQHINWVRCAKFSPD--GRLIVSASDDKTVKLWDKSSRE 212
Query: 535 LKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHL-HTLDHNDIITALCFS 359
++ H G++ V P G+ A+ G D +WD+ + L H H+ + L F
Sbjct: 213 CVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNGLSFH 272
Query: 358 PN-RYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLF 182
P+ Y + A+ ++KI DL ++ L Q T ++A+S G+
Sbjct: 273 PSGNYLITASSDSTLKILDLMEGRLLYTLHGH-----QGPAT------TVAFSRTGEYFA 321
Query: 181 AGYSDNTIRVWQ 146
+G SD + VW+
Sbjct: 322 SGGSDEQVMVWK 333
Score = 68.9 bits (161), Expect = 2e-11
Identities = 41/148 (27%), Positives = 72/148 (48%), Gaps = 2/148 (1%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
GSRDKT+++W + + T+ H+ V V F + + V+ D+TVKVW
Sbjct: 113 GSRDKTVRIWVPNVKGESTVFR-AHTATVRSVHFCSDGQS--FVTASDDKTVKVWATHRQ 169
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHT-LDHNDIITALCF 362
K + H ++ SPDG L S D LWD + + +H+ +H +T + F
Sbjct: 170 KFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVHSYCEHGGFVTYVDF 229
Query: 361 SPNRYWLCAA-FGPSIKIWDLESKEMVE 281
P+ + AA ++K+WD+ + +++
Sbjct: 230 HPSGTCIAAAGMDNTVKVWDVRTHRLLQ 257
Score = 61.7 bits (143), Expect = 3e-09
Identities = 45/172 (26%), Positives = 75/172 (43%), Gaps = 2/172 (1%)
Frame = -2
Query: 649 GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGS 470
GH D V+CV FS N + S D + VWH+ GH + V SP G
Sbjct: 51 GHRDAVTCVDFSINTKQ--LASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPSGH 108
Query: 469 LCASGGKDMKAMLWDLN-DGKHLHTLDHNDIITALCF-SPNRYWLCAAFGPSIKIWDLES 296
L ASG +D +W N G+ H + ++ F S + ++ A+ ++K+W
Sbjct: 109 LLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVWATHR 168
Query: 295 KEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQVS 140
++ + L + IN + +K P DG+ + + D T+++W S
Sbjct: 169 QKFLFSL-SQHINWVRCAKFSP----------DGRLIVSASDDKTVKLWDKS 209
Score = 60.1 bits (139), Expect = 8e-09
Identities = 50/195 (25%), Positives = 85/195 (43%), Gaps = 3/195 (1%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
GS D + +W+ + + + GH D V+CV FSP+ ++ S D+TV++W + N
Sbjct: 71 GSMDSCLMVWHMKPQSR-AYRFTGHKDAVTCVNFSPS--GHLLASGSRDKTVRIW-VPNV 126
Query: 538 KLKINHL-GHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALC 365
K + H+ + +V DG + D +W + K L +L H + +
Sbjct: 127 KGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVWATHRQKFLFSLSQHINWVRCAK 186
Query: 364 FSPN-RYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQT 188
FSP+ R + A+ ++K+WD S+E V T + G
Sbjct: 187 FSPDGRLIVSASDDKTVKLWDKSSRECVHSYCEHGGFVTYVD-----------FHPSGTC 235
Query: 187 LFAGYSDNTIRVWQV 143
+ A DNT++VW V
Sbjct: 236 IAAAGMDNTVKVWDV 250
Score = 46.4 bits (105), Expect = 1e-04
Identities = 31/110 (28%), Positives = 49/110 (44%)
Frame = -2
Query: 709 DKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLK 530
D T+K+W+ + HS V+ + F P+ +++ D T+K+ L +L
Sbjct: 242 DNTVKVWDVRTH-RLLQHYQLHSAAVNGLSFHPS--GNYLITASSDSTLKILDLMEGRLL 298
Query: 529 INHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDI 380
GH G TV S G ASGG D + M+W N +DH ++
Sbjct: 299 YTLHGHQGPATTVAFSRTGEYFASGGSDEQVMVWKSN----FDIVDHGEV 344
>BC119692-1|AAI19693.1| 407|Homo sapiens WD repeat domain 51A
protein.
Length = 407
Score = 83.4 bits (197), Expect = 7e-16
Identities = 56/192 (29%), Positives = 94/192 (48%), Gaps = 2/192 (1%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK 536
S DKT+K+W T + K+ H +WV C +FSP+ +IVS D+TVK+W ++ +
Sbjct: 122 SDDKTVKVWATHRQ-KFLFSLSQHINWVRCAKFSPD--GRLIVSASDDKTVKLWDKSSRE 178
Query: 535 LKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHL-HTLDHNDIITALCFS 359
++ H G++ V P G+ A+ G D +WD+ + L H H+ + L F
Sbjct: 179 CVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNGLSFH 238
Query: 358 PN-RYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLF 182
P+ Y + A+ ++KI DL ++ L Q T ++A+S G+
Sbjct: 239 PSGNYLITASSDSTLKILDLMEGRLLYTLHGH-----QGPAT------TVAFSRTGEYFA 287
Query: 181 AGYSDNTIRVWQ 146
+G SD + VW+
Sbjct: 288 SGGSDEQVMVWK 299
Score = 68.9 bits (161), Expect = 2e-11
Identities = 41/148 (27%), Positives = 72/148 (48%), Gaps = 2/148 (1%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
GSRDKT+++W + + T+ H+ V V F + + V+ D+TVKVW
Sbjct: 79 GSRDKTVRIWVPNVKGESTVFR-AHTATVRSVHFCSDGQS--FVTASDDKTVKVWATHRQ 135
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHT-LDHNDIITALCF 362
K + H ++ SPDG L S D LWD + + +H+ +H +T + F
Sbjct: 136 KFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVHSYCEHGGFVTYVDF 195
Query: 361 SPNRYWLCAA-FGPSIKIWDLESKEMVE 281
P+ + AA ++K+WD+ + +++
Sbjct: 196 HPSGTCIAAAGMDNTVKVWDVRTHRLLQ 223
Score = 61.7 bits (143), Expect = 3e-09
Identities = 45/172 (26%), Positives = 75/172 (43%), Gaps = 2/172 (1%)
Frame = -2
Query: 649 GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGS 470
GH D V+CV FS N + S D + VWH+ GH + V SP G
Sbjct: 17 GHRDAVTCVDFSINTKQ--LASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPSGH 74
Query: 469 LCASGGKDMKAMLWDLN-DGKHLHTLDHNDIITALCF-SPNRYWLCAAFGPSIKIWDLES 296
L ASG +D +W N G+ H + ++ F S + ++ A+ ++K+W
Sbjct: 75 LLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVWATHR 134
Query: 295 KEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQVS 140
++ + L + IN + +K P DG+ + + D T+++W S
Sbjct: 135 QKFLFSL-SQHINWVRCAKFSP----------DGRLIVSASDDKTVKLWDKS 175
Score = 60.1 bits (139), Expect = 8e-09
Identities = 50/195 (25%), Positives = 85/195 (43%), Gaps = 3/195 (1%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
GS D + +W+ + + + GH D V+CV FSP+ ++ S D+TV++W + N
Sbjct: 37 GSMDSCLMVWHMKPQSR-AYRFTGHKDAVTCVNFSPS--GHLLASGSRDKTVRIW-VPNV 92
Query: 538 KLKINHL-GHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALC 365
K + H+ + +V DG + D +W + K L +L H + +
Sbjct: 93 KGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVWATHRQKFLFSLSQHINWVRCAK 152
Query: 364 FSPN-RYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQT 188
FSP+ R + A+ ++K+WD S+E V T + G
Sbjct: 153 FSPDGRLIVSASDDKTVKLWDKSSRECVHSYCEHGGFVTYVD-----------FHPSGTC 201
Query: 187 LFAGYSDNTIRVWQV 143
+ A DNT++VW V
Sbjct: 202 IAAAGMDNTVKVWDV 216
Score = 46.4 bits (105), Expect = 1e-04
Identities = 31/110 (28%), Positives = 49/110 (44%)
Frame = -2
Query: 709 DKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLK 530
D T+K+W+ + HS V+ + F P+ +++ D T+K+ L +L
Sbjct: 208 DNTVKVWDVRTH-RLLQHYQLHSAAVNGLSFHPS--GNYLITASSDSTLKILDLMEGRLL 264
Query: 529 INHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDI 380
GH G TV S G ASGG D + M+W N +DH ++
Sbjct: 265 YTLHGHQGPATTVAFSRTGEYFASGGSDEQVMVWKSN----FDIVDHGEV 310
>BC110877-1|AAI10878.1| 359|Homo sapiens WDR51A protein protein.
Length = 359
Score = 83.4 bits (197), Expect = 7e-16
Identities = 56/192 (29%), Positives = 94/192 (48%), Gaps = 2/192 (1%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK 536
S DKT+K+W T + K+ H +WV C +FSP+ +IVS D+TVK+W ++ +
Sbjct: 122 SDDKTVKVWATHRQ-KFLFSLSQHINWVRCAKFSPD--GRLIVSASDDKTVKLWDKSSRE 178
Query: 535 LKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHL-HTLDHNDIITALCFS 359
++ H G++ V P G+ A+ G D +WD+ + L H H+ + L F
Sbjct: 179 CVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNGLSFH 238
Query: 358 PN-RYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLF 182
P+ Y + A+ ++KI DL ++ L Q T ++A+S G+
Sbjct: 239 PSGNYLITASSDSTLKILDLMEGRLLYTLHGH-----QGPAT------TVAFSRTGEYFA 287
Query: 181 AGYSDNTIRVWQ 146
+G SD + VW+
Sbjct: 288 SGGSDEQVMVWK 299
Score = 68.9 bits (161), Expect = 2e-11
Identities = 41/148 (27%), Positives = 72/148 (48%), Gaps = 2/148 (1%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
GSRDKT+++W + + T+ H+ V V F + + V+ D+TVKVW
Sbjct: 79 GSRDKTVRIWVPNVKGESTVFR-AHTATVRSVHFCSDGQS--FVTASDDKTVKVWATHRQ 135
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHT-LDHNDIITALCF 362
K + H ++ SPDG L S D LWD + + +H+ +H +T + F
Sbjct: 136 KFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVHSYCEHGGFVTYVDF 195
Query: 361 SPNRYWLCAA-FGPSIKIWDLESKEMVE 281
P+ + AA ++K+WD+ + +++
Sbjct: 196 HPSGTCIAAAGMDNTVKVWDVRTHRLLQ 223
Score = 61.7 bits (143), Expect = 3e-09
Identities = 45/172 (26%), Positives = 75/172 (43%), Gaps = 2/172 (1%)
Frame = -2
Query: 649 GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGS 470
GH D V+CV FS N + S D + VWH+ GH + V SP G
Sbjct: 17 GHRDAVTCVDFSINTKQ--LASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPSGH 74
Query: 469 LCASGGKDMKAMLWDLN-DGKHLHTLDHNDIITALCF-SPNRYWLCAAFGPSIKIWDLES 296
L ASG +D +W N G+ H + ++ F S + ++ A+ ++K+W
Sbjct: 75 LLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVWATHR 134
Query: 295 KEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQVS 140
++ + L + IN + +K P DG+ + + D T+++W S
Sbjct: 135 QKFLFSL-SQHINWVRCAKFSP----------DGRLIVSASDDKTVKLWDKS 175
Score = 60.1 bits (139), Expect = 8e-09
Identities = 50/195 (25%), Positives = 85/195 (43%), Gaps = 3/195 (1%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
GS D + +W+ + + + GH D V+CV FSP+ ++ S D+TV++W + N
Sbjct: 37 GSMDSCLMVWHMKPQSR-AYRFTGHKDAVTCVNFSPS--GHLLASGSRDKTVRIW-VPNV 92
Query: 538 KLKINHL-GHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALC 365
K + H+ + +V DG + D +W + K L +L H + +
Sbjct: 93 KGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVWATHRQKFLFSLSQHINWVRCAK 152
Query: 364 FSPN-RYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQT 188
FSP+ R + A+ ++K+WD S+E V T + G
Sbjct: 153 FSPDGRLIVSASDDKTVKLWDKSSRECVHSYCEHGGFVTYVD-----------FHPSGTC 201
Query: 187 LFAGYSDNTIRVWQV 143
+ A DNT++VW V
Sbjct: 202 IAAAGMDNTVKVWDV 216
Score = 46.4 bits (105), Expect = 1e-04
Identities = 31/110 (28%), Positives = 49/110 (44%)
Frame = -2
Query: 709 DKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLK 530
D T+K+W+ + HS V+ + F P+ +++ D T+K+ L +L
Sbjct: 208 DNTVKVWDVRTH-RLLQHYQLHSAAVNGLSFHPS--GNYLITASSDSTLKILDLMEGRLL 264
Query: 529 INHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDI 380
GH G TV S G ASGG D + M+W N +DH ++
Sbjct: 265 YTLHGHQGPATTVAFSRTGEYFASGGSDEQVMVWKSN----FDIVDHGEV 310
>BC007417-1|AAH07417.2| 396|Homo sapiens WDR51A protein protein.
Length = 396
Score = 83.4 bits (197), Expect = 7e-16
Identities = 56/192 (29%), Positives = 94/192 (48%), Gaps = 2/192 (1%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK 536
S DKT+K+W T + K+ H +WV C +FSP+ +IVS D+TVK+W ++ +
Sbjct: 111 SDDKTVKVWATHRQ-KFLFSLSQHINWVRCAKFSPD--GRLIVSASDDKTVKLWDKSSRE 167
Query: 535 LKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHL-HTLDHNDIITALCFS 359
++ H G++ V P G+ A+ G D +WD+ + L H H+ + L F
Sbjct: 168 CVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNGLSFH 227
Query: 358 PN-RYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLF 182
P+ Y + A+ ++KI DL ++ L Q T ++A+S G+
Sbjct: 228 PSGNYLITASSDSTLKILDLMEGRLLYTLHGH-----QGPAT------TVAFSRTGEYFA 276
Query: 181 AGYSDNTIRVWQ 146
+G SD + VW+
Sbjct: 277 SGGSDEQVMVWK 288
Score = 68.9 bits (161), Expect = 2e-11
Identities = 41/148 (27%), Positives = 72/148 (48%), Gaps = 2/148 (1%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
GSRDKT+++W + + T+ H+ V V F + + V+ D+TVKVW
Sbjct: 68 GSRDKTVRIWVPNVKGESTVFR-AHTATVRSVHFCSDGQS--FVTASDDKTVKVWATHRQ 124
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHT-LDHNDIITALCF 362
K + H ++ SPDG L S D LWD + + +H+ +H +T + F
Sbjct: 125 KFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVHSYCEHGGFVTYVDF 184
Query: 361 SPNRYWLCAA-FGPSIKIWDLESKEMVE 281
P+ + AA ++K+WD+ + +++
Sbjct: 185 HPSGTCIAAAGMDNTVKVWDVRTHRLLQ 212
Score = 61.7 bits (143), Expect = 3e-09
Identities = 45/172 (26%), Positives = 75/172 (43%), Gaps = 2/172 (1%)
Frame = -2
Query: 649 GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGS 470
GH D V+CV FS N + S D + VWH+ GH + V SP G
Sbjct: 6 GHRDAVTCVDFSINTKQ--LASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPSGH 63
Query: 469 LCASGGKDMKAMLWDLN-DGKHLHTLDHNDIITALCF-SPNRYWLCAAFGPSIKIWDLES 296
L ASG +D +W N G+ H + ++ F S + ++ A+ ++K+W
Sbjct: 64 LLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVWATHR 123
Query: 295 KEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQVS 140
++ + L + IN + +K P DG+ + + D T+++W S
Sbjct: 124 QKFLFSL-SQHINWVRCAKFSP----------DGRLIVSASDDKTVKLWDKS 164
Score = 60.1 bits (139), Expect = 8e-09
Identities = 50/195 (25%), Positives = 85/195 (43%), Gaps = 3/195 (1%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
GS D + +W+ + + + GH D V+CV FSP+ ++ S D+TV++W + N
Sbjct: 26 GSMDSCLMVWHMKPQSR-AYRFTGHKDAVTCVNFSPS--GHLLASGSRDKTVRIW-VPNV 81
Query: 538 KLKINHL-GHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALC 365
K + H+ + +V DG + D +W + K L +L H + +
Sbjct: 82 KGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVWATHRQKFLFSLSQHINWVRCAK 141
Query: 364 FSPN-RYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQT 188
FSP+ R + A+ ++K+WD S+E V T + G
Sbjct: 142 FSPDGRLIVSASDDKTVKLWDKSSRECVHSYCEHGGFVTYVD-----------FHPSGTC 190
Query: 187 LFAGYSDNTIRVWQV 143
+ A DNT++VW V
Sbjct: 191 IAAAGMDNTVKVWDV 205
Score = 46.4 bits (105), Expect = 1e-04
Identities = 31/110 (28%), Positives = 49/110 (44%)
Frame = -2
Query: 709 DKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLK 530
D T+K+W+ + HS V+ + F P+ +++ D T+K+ L +L
Sbjct: 197 DNTVKVWDVRTH-RLLQHYQLHSAAVNGLSFHPS--GNYLITASSDSTLKILDLMEGRLL 253
Query: 529 INHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDI 380
GH G TV S G ASGG D + M+W N +DH ++
Sbjct: 254 YTLHGHQGPATTVAFSRTGEYFASGGSDEQVMVWKSN----FDIVDHGEV 299
>AK075289-1|BAC11525.1| 407|Homo sapiens protein ( Homo sapiens
cDNA FLJ90808 fis, clone Y79AA1000777, weakly similar to
VEGETATIBLE INCOMPATIBILITY PROTEIN HET-E-1. ).
Length = 407
Score = 83.0 bits (196), Expect = 1e-15
Identities = 56/192 (29%), Positives = 94/192 (48%), Gaps = 2/192 (1%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK 536
S DKT+K+W T + K+ H +WV C +FSP+ +IVS D+TVK+W ++ +
Sbjct: 122 SDDKTVKVWATHRQ-KFLFSLSQHINWVRCAKFSPD--GRLIVSASDDKTVKLWDKSSRE 178
Query: 535 LKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHL-HTLDHNDIITALCFS 359
++ H G++ V P G+ A+ G D +WD+ + L H H+ + L F
Sbjct: 179 CVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTYRLLQHYQLHSAAVNGLSFH 238
Query: 358 PN-RYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLF 182
P+ Y + A+ ++KI DL ++ L Q T ++A+S G+
Sbjct: 239 PSGNYLITASSDSTLKILDLMEGRLLYTLHGH-----QGPAT------TVAFSRTGEYFA 287
Query: 181 AGYSDNTIRVWQ 146
+G SD + VW+
Sbjct: 288 SGGSDEQVMVWK 299
Score = 68.5 bits (160), Expect = 2e-11
Identities = 41/148 (27%), Positives = 72/148 (48%), Gaps = 2/148 (1%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
GSRDKT+++W + + T+ H+ V V F + + V+ D+TVKVW
Sbjct: 79 GSRDKTVRIWVPNVKGESTVFR-AHTATVRSVHFCSDGQS--FVTASDDKTVKVWATHRQ 135
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHT-LDHNDIITALCF 362
K + H ++ SPDG L S D LWD + + +H+ +H +T + F
Sbjct: 136 KFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVHSYCEHGGFVTYVDF 195
Query: 361 SPNRYWLCAA-FGPSIKIWDLESKEMVE 281
P+ + AA ++K+WD+ + +++
Sbjct: 196 HPSGTCIAAAGMDNTVKVWDVRTYRLLQ 223
Score = 61.7 bits (143), Expect = 3e-09
Identities = 45/172 (26%), Positives = 75/172 (43%), Gaps = 2/172 (1%)
Frame = -2
Query: 649 GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGS 470
GH D V+CV FS N + S D + VWH+ GH + V SP G
Sbjct: 17 GHRDAVTCVDFSINTKQ--LASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPSGH 74
Query: 469 LCASGGKDMKAMLWDLN-DGKHLHTLDHNDIITALCF-SPNRYWLCAAFGPSIKIWDLES 296
L ASG +D +W N G+ H + ++ F S + ++ A+ ++K+W
Sbjct: 75 LLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVWATHR 134
Query: 295 KEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQVS 140
++ + L + IN + +K P DG+ + + D T+++W S
Sbjct: 135 QKFLFSL-SQHINWVRCAKFSP----------DGRLIVSASDDKTVKLWDKS 175
Score = 60.1 bits (139), Expect = 8e-09
Identities = 50/195 (25%), Positives = 85/195 (43%), Gaps = 3/195 (1%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
GS D + +W+ + + + GH D V+CV FSP+ ++ S D+TV++W + N
Sbjct: 37 GSMDSCLMVWHMKPQSR-AYRFTGHKDAVTCVNFSPS--GHLLASGSRDKTVRIW-VPNV 92
Query: 538 KLKINHL-GHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALC 365
K + H+ + +V DG + D +W + K L +L H + +
Sbjct: 93 KGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVWATHRQKFLFSLSQHINWVRCAK 152
Query: 364 FSPN-RYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQT 188
FSP+ R + A+ ++K+WD S+E V T + G
Sbjct: 153 FSPDGRLIVSASDDKTVKLWDKSSRECVHSYCEHGGFVTYVD-----------FHPSGTC 201
Query: 187 LFAGYSDNTIRVWQV 143
+ A DNT++VW V
Sbjct: 202 IAAAGMDNTVKVWDV 216
Score = 46.0 bits (104), Expect = 1e-04
Identities = 31/110 (28%), Positives = 50/110 (45%)
Frame = -2
Query: 709 DKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLK 530
D T+K+W+ + + HS V+ + F P+ +++ D T+K+ L +L
Sbjct: 208 DNTVKVWD-VRTYRLLQHYQLHSAAVNGLSFHPS--GNYLITASSDSTLKILDLMEGRLL 264
Query: 529 INHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDI 380
GH G TV S G ASGG D + M+W N +DH ++
Sbjct: 265 YTLHGHQGPATTVAFSRTGEYFASGGSDEQVMVWKSN----FDIVDHGEV 310
>BT009800-1|AAP88802.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 3 protein.
Length = 340
Score = 82.6 bits (195), Expect = 1e-15
Identities = 58/175 (33%), Positives = 86/175 (49%), Gaps = 2/175 (1%)
Frame = -2
Query: 646 HSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSL 467
H+ ++SC RF + N I+ S G D T +W + + K +GH+G ++ VSPD +L
Sbjct: 142 HTGYLSCCRFLDD--NNIVTSSG-DTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDFNL 198
Query: 466 CASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCFSPNRYWLC-AAFGPSIKIWDLESK 293
SG D A LWD+ +G T H I A+CF PN +C + S +++DL +
Sbjct: 199 FISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRAD 258
Query: 292 EMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQVSISAR 128
+ + E I + T S+A+S G+ LFAGY D VW S R
Sbjct: 259 QELICFSHESIICSIT---------SVAFSLSGRLLFAGYDDFNCNVWDSMKSER 304
Score = 42.3 bits (95), Expect = 0.002
Identities = 33/121 (27%), Positives = 54/121 (44%), Gaps = 7/121 (5%)
Frame = -2
Query: 643 SDWVSCVRFSPNHANPIIVSCGW-DRTVKVWHLT----NCKLKINHLGHSGYLNTVTVSP 479
S WV ++P+ N V+CG D +++L N K+ H+GYL+
Sbjct: 97 SSWVMTCAYAPS-GN--FVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLD 153
Query: 478 DGSLCASGGKDMKAMLWDLNDGKHLHT-LDHNDIITALCFSPN-RYWLCAAFGPSIKIWD 305
D ++ S G D LWD+ G+ + H +L SP+ ++ A S K+WD
Sbjct: 154 DNNIVTSSG-DTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWD 212
Query: 304 L 302
+
Sbjct: 213 V 213
>BC002454-1|AAH02454.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 3 protein.
Length = 340
Score = 82.6 bits (195), Expect = 1e-15
Identities = 58/175 (33%), Positives = 86/175 (49%), Gaps = 2/175 (1%)
Frame = -2
Query: 646 HSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSL 467
H+ ++SC RF + N I+ S G D T +W + + K +GH+G ++ VSPD +L
Sbjct: 142 HTGYLSCCRFLDD--NNIVTSSG-DTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDFNL 198
Query: 466 CASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCFSPNRYWLC-AAFGPSIKIWDLESK 293
SG D A LWD+ +G T H I A+CF PN +C + S +++DL +
Sbjct: 199 FISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRAD 258
Query: 292 EMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQVSISAR 128
+ + E I + T S+A+S G+ LFAGY D VW S R
Sbjct: 259 QELICFSHESIICSIT---------SVAFSLSGRLLFAGYDDFNCNVWDSMKSER 304
Score = 42.3 bits (95), Expect = 0.002
Identities = 33/121 (27%), Positives = 54/121 (44%), Gaps = 7/121 (5%)
Frame = -2
Query: 643 SDWVSCVRFSPNHANPIIVSCGW-DRTVKVWHLT----NCKLKINHLGHSGYLNTVTVSP 479
S WV ++P+ N V+CG D +++L N K+ H+GYL+
Sbjct: 97 SSWVMTCAYAPS-GN--FVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLD 153
Query: 478 DGSLCASGGKDMKAMLWDLNDGKHLHT-LDHNDIITALCFSPN-RYWLCAAFGPSIKIWD 305
D ++ S G D LWD+ G+ + H +L SP+ ++ A S K+WD
Sbjct: 154 DNNIVTSSG-DTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWD 212
Query: 304 L 302
+
Sbjct: 213 V 213
>BC000115-1|AAH00115.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 3 protein.
Length = 340
Score = 82.6 bits (195), Expect = 1e-15
Identities = 58/175 (33%), Positives = 86/175 (49%), Gaps = 2/175 (1%)
Frame = -2
Query: 646 HSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSL 467
H+ ++SC RF + N I+ S G D T +W + + K +GH+G ++ VSPD +L
Sbjct: 142 HTGYLSCCRFLDD--NNIVTSSG-DTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDFNL 198
Query: 466 CASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCFSPNRYWLC-AAFGPSIKIWDLESK 293
SG D A LWD+ +G T H I A+CF PN +C + S +++DL +
Sbjct: 199 FISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRAD 258
Query: 292 EMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQVSISAR 128
+ + E I + T S+A+S G+ LFAGY D VW S R
Sbjct: 259 QELICFSHESIICSIT---------SVAFSLSGRLLFAGYDDFNCNVWDSMKSER 304
Score = 42.3 bits (95), Expect = 0.002
Identities = 33/121 (27%), Positives = 54/121 (44%), Gaps = 7/121 (5%)
Frame = -2
Query: 643 SDWVSCVRFSPNHANPIIVSCGW-DRTVKVWHLT----NCKLKINHLGHSGYLNTVTVSP 479
S WV ++P+ N V+CG D +++L N K+ H+GYL+
Sbjct: 97 SSWVMTCAYAPS-GN--FVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLD 153
Query: 478 DGSLCASGGKDMKAMLWDLNDGKHLHT-LDHNDIITALCFSPN-RYWLCAAFGPSIKIWD 305
D ++ S G D LWD+ G+ + H +L SP+ ++ A S K+WD
Sbjct: 154 DNNIVTSSG-DTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWD 212
Query: 304 L 302
+
Sbjct: 213 V 213
>Y12050-1|CAA72779.1| 340|Homo sapiens guanine nucleotide-binding
protein beta3 subunit protein.
Length = 340
Score = 81.4 bits (192), Expect = 3e-15
Identities = 58/175 (33%), Positives = 85/175 (48%), Gaps = 2/175 (1%)
Frame = -2
Query: 646 HSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSL 467
H+ ++SC RF + N I+ S G D T +W + + K +GH+G ++ VSPD +L
Sbjct: 142 HTGYLSCCRFLDD--NNIVTSSG-DTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDFNL 198
Query: 466 CASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCFSPNRYWLC-AAFGPSIKIWDLESK 293
SG D A LWD+ +G T H I A+CF PN +C + S +++DL +
Sbjct: 199 FISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRAD 258
Query: 292 EMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQVSISAR 128
+ + E I T S+A+S G+ LFAGY D VW S R
Sbjct: 259 QELICFSHESIICGIT---------SVAFSLSGRLLFAGYDDFNCNVWDSMKSER 304
Score = 42.3 bits (95), Expect = 0.002
Identities = 33/121 (27%), Positives = 54/121 (44%), Gaps = 7/121 (5%)
Frame = -2
Query: 643 SDWVSCVRFSPNHANPIIVSCGW-DRTVKVWHLT----NCKLKINHLGHSGYLNTVTVSP 479
S WV ++P+ N V+CG D +++L N K+ H+GYL+
Sbjct: 97 SSWVMTCAYAPS-GN--FVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLD 153
Query: 478 DGSLCASGGKDMKAMLWDLNDGKHLHT-LDHNDIITALCFSPN-RYWLCAAFGPSIKIWD 305
D ++ S G D LWD+ G+ + H +L SP+ ++ A S K+WD
Sbjct: 154 DNNIVTSSG-DTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWD 212
Query: 304 L 302
+
Sbjct: 213 V 213
>U47924-5|AAB51313.1| 340|Homo sapiens G-protein beta-3 chain
protein.
Length = 340
Score = 81.4 bits (192), Expect = 3e-15
Identities = 58/175 (33%), Positives = 85/175 (48%), Gaps = 2/175 (1%)
Frame = -2
Query: 646 HSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSL 467
H+ ++SC RF + N I+ S G D T +W + + K +GH+G ++ VSPD +L
Sbjct: 142 HTGYLSCCRFLDD--NNIVTSSG-DTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDFNL 198
Query: 466 CASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCFSPNRYWLC-AAFGPSIKIWDLESK 293
SG D A LWD+ +G T H I A+CF PN +C + S +++DL +
Sbjct: 199 FISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRAD 258
Query: 292 EMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQVSISAR 128
+ + E I T S+A+S G+ LFAGY D VW S R
Sbjct: 259 QELICFSHESIICGIT---------SVAFSLSGRLLFAGYDDFNCNVWDSMKSER 304
Score = 42.3 bits (95), Expect = 0.002
Identities = 33/121 (27%), Positives = 54/121 (44%), Gaps = 7/121 (5%)
Frame = -2
Query: 643 SDWVSCVRFSPNHANPIIVSCGW-DRTVKVWHLT----NCKLKINHLGHSGYLNTVTVSP 479
S WV ++P+ N V+CG D +++L N K+ H+GYL+
Sbjct: 97 SSWVMTCAYAPS-GN--FVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLD 153
Query: 478 DGSLCASGGKDMKAMLWDLNDGKHLHT-LDHNDIITALCFSPN-RYWLCAAFGPSIKIWD 305
D ++ S G D LWD+ G+ + H +L SP+ ++ A S K+WD
Sbjct: 154 DNNIVTSSG-DTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWD 212
Query: 304 L 302
+
Sbjct: 213 V 213
>M31328-1|AAA52582.1| 340|Homo sapiens GNB3 protein.
Length = 340
Score = 81.4 bits (192), Expect = 3e-15
Identities = 58/175 (33%), Positives = 85/175 (48%), Gaps = 2/175 (1%)
Frame = -2
Query: 646 HSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSL 467
H+ ++SC RF + N I+ S G D T +W + + K +GH+G ++ VSPD +L
Sbjct: 142 HTGYLSCCRFLDD--NNIVTSSG-DTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDFNL 198
Query: 466 CASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCFSPNRYWLC-AAFGPSIKIWDLESK 293
SG D A LWD+ +G T H I A+CF PN +C + S +++DL +
Sbjct: 199 FISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRAD 258
Query: 292 EMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQVSISAR 128
+ + E I T S+A+S G+ LFAGY D VW S R
Sbjct: 259 QELICFSHESIICGIT---------SVAFSLSGRLLFAGYDDFNCNVWDSMKSER 304
Score = 42.3 bits (95), Expect = 0.002
Identities = 33/121 (27%), Positives = 54/121 (44%), Gaps = 7/121 (5%)
Frame = -2
Query: 643 SDWVSCVRFSPNHANPIIVSCGW-DRTVKVWHLT----NCKLKINHLGHSGYLNTVTVSP 479
S WV ++P+ N V+CG D +++L N K+ H+GYL+
Sbjct: 97 SSWVMTCAYAPS-GN--FVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLD 153
Query: 478 DGSLCASGGKDMKAMLWDLNDGKHLHT-LDHNDIITALCFSPN-RYWLCAAFGPSIKIWD 305
D ++ S G D LWD+ G+ + H +L SP+ ++ A S K+WD
Sbjct: 154 DNNIVTSSG-DTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWD 212
Query: 304 L 302
+
Sbjct: 213 V 213
>BC127949-1|AAI27950.1| 314|Homo sapiens WD repeat domain 38
protein.
Length = 314
Score = 81.4 bits (192), Expect = 3e-15
Identities = 61/198 (30%), Positives = 92/198 (46%), Gaps = 2/198 (1%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
GS D + W T + + + GH+ V RFSP+ + S D TV++W +
Sbjct: 39 GSEDGCVYGWETRSG-QLLWRLGGHTGPVKFCRFSPD--GHLFASASCDCTVRLWDVARA 95
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCF 362
K GH + TV+ SPD ASGG D + MLWD+ G+ L L H D I + F
Sbjct: 96 KCLRVLKGHQRSVETVSFSPDSRQLASGGWDKRVMLWDVQSGQMLRLLVGHRDSIQSSDF 155
Query: 361 SPNRYWLC-AAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTL 185
SP L ++ +++IWDL + P + +Q + C L +S G L
Sbjct: 156 SPTVNCLATGSWDSTVRIWDLRM------VTPAVSHQALEGHSGNISC--LCYSASG-LL 206
Query: 184 FAGYSDNTIRVWQVSISA 131
+G D TI +W+ + S+
Sbjct: 207 ASGSWDKTIHIWKPTTSS 224
Score = 69.7 bits (163), Expect = 1e-11
Identities = 39/125 (31%), Positives = 61/125 (48%), Gaps = 3/125 (2%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQD--DGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 545
GS D T+++W+ +GHS +SC+ +S A+ ++ S WD+T+ +W T
Sbjct: 165 GSWDSTVRIWDLRMVTPAVSHQALEGHSGNISCLCYS---ASGLLASGSWDKTIHIWKPT 221
Query: 544 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDH-NDIITAL 368
L I GH ++ ++ SPD AS G +WD N GK L TL D+
Sbjct: 222 TSSLLIQLKGHVTWVKSIAFSPDELWLASAGYSRMVKVWDCNTGKCLETLKGVLDVAHTC 281
Query: 367 CFSPN 353
F+P+
Sbjct: 282 AFTPD 286
Score = 68.5 bits (160), Expect = 2e-11
Identities = 55/193 (28%), Positives = 90/193 (46%), Gaps = 5/193 (2%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
G DK + LW+ + + GH D + FSP N + + WD TV++W L
Sbjct: 123 GGWDKRVMLWDVQSGQMLRLLV-GHRDSIQSSDFSPT-VN-CLATGSWDSTVRIWDLRMV 179
Query: 538 KLKINHL---GHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITA 371
++H GHSG ++ + S G L ASG D +W L L H + +
Sbjct: 180 TPAVSHQALEGHSGNISCLCYSASG-LLASGSWDKTIHIWKPTTSSLLIQLKGHVTWVKS 238
Query: 370 LCFSPNRYWLCAA-FGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDG 194
+ FSP+ WL +A + +K+WD + + +E L+ +++ T C A++ DG
Sbjct: 239 IAFSPDELWLASAGYSRMVKVWDCNTGKCLETLK-GVLDVAHT-------C---AFTPDG 287
Query: 193 QTLFAGYSDNTIR 155
+ L +G +D T R
Sbjct: 288 KILVSGAADQTRR 300
Score = 60.9 bits (141), Expect = 4e-09
Identities = 40/156 (25%), Positives = 73/156 (46%), Gaps = 5/156 (3%)
Frame = -2
Query: 715 SRDKTIKLWNTL-AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
S D T++LW+ A+C ++ GH V V FSP+ + S GWD+ V +W + +
Sbjct: 82 SCDCTVRLWDVARAKCLRVLK--GHQRSVETVSFSPDSRQ--LASGGWDKRVMLWDVQSG 137
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLN----DGKHLHTLDHNDIITA 371
++ +GH + + SP + A+G D +WDL H H+ I+
Sbjct: 138 QMLRLLVGHRDSIQSSDFSPTVNCLATGSWDSTVRIWDLRMVTPAVSHQALEGHSGNISC 197
Query: 370 LCFSPNRYWLCAAFGPSIKIWDLESKEMVEELRPEI 263
LC+S + ++ +I IW + ++ +L+ +
Sbjct: 198 LCYSASGLLASGSWDKTIHIWKPTTSSLLIQLKGHV 233
Score = 39.5 bits (88), Expect = 0.012
Identities = 29/126 (23%), Positives = 59/126 (46%), Gaps = 2/126 (1%)
Frame = -2
Query: 514 HSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCFSPNRY-WL 341
H G +N+ SPDG + +G +D W+ G+ L L H + FSP+ + +
Sbjct: 20 HGGEVNSSAFSPDGQMLLTGSEDGCVYGWETRSGQLLWRLGGHTGPVKFCRFSPDGHLFA 79
Query: 340 CAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNT 161
A+ ++++WD+ + + L+ ++ +T +++S D + L +G D
Sbjct: 80 SASCDCTVRLWDVARAKCLRVLK----GHQRSVET-------VSFSPDSRQLASGGWDKR 128
Query: 160 IRVWQV 143
+ +W V
Sbjct: 129 VMLWDV 134
>AY631872-1|AAT38116.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 3 protein.
Length = 340
Score = 81.4 bits (192), Expect = 3e-15
Identities = 58/175 (33%), Positives = 85/175 (48%), Gaps = 2/175 (1%)
Frame = -2
Query: 646 HSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSL 467
H+ ++SC RF + N I+ S G D T +W + + K +GH+G ++ VSPD +L
Sbjct: 142 HTGYLSCCRFLDD--NNIVTSSG-DTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDFNL 198
Query: 466 CASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCFSPNRYWLC-AAFGPSIKIWDLESK 293
SG D A LWD+ +G T H I A+CF PN +C + S +++DL +
Sbjct: 199 FISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRAD 258
Query: 292 EMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQVSISAR 128
+ + E I T S+A+S G+ LFAGY D VW S R
Sbjct: 259 QELICFSHESIICGIT---------SVAFSLSGRLLFAGYDDFNCNVWDSMKSER 304
Score = 42.3 bits (95), Expect = 0.002
Identities = 33/121 (27%), Positives = 54/121 (44%), Gaps = 7/121 (5%)
Frame = -2
Query: 643 SDWVSCVRFSPNHANPIIVSCGW-DRTVKVWHLT----NCKLKINHLGHSGYLNTVTVSP 479
S WV ++P+ N V+CG D +++L N K+ H+GYL+
Sbjct: 97 SSWVMTCAYAPS-GN--FVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLD 153
Query: 478 DGSLCASGGKDMKAMLWDLNDGKHLHT-LDHNDIITALCFSPN-RYWLCAAFGPSIKIWD 305
D ++ S G D LWD+ G+ + H +L SP+ ++ A S K+WD
Sbjct: 154 DNNIVTSSG-DTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWD 212
Query: 304 L 302
+
Sbjct: 213 V 213
>AF501884-1|AAM15920.1| 340|Homo sapiens guanine nucleotide binding
protein beta 3 protein.
Length = 340
Score = 81.4 bits (192), Expect = 3e-15
Identities = 58/175 (33%), Positives = 85/175 (48%), Gaps = 2/175 (1%)
Frame = -2
Query: 646 HSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSL 467
H+ ++SC RF + N I+ S G D T +W + + K +GH+G ++ VSPD +L
Sbjct: 142 HTGYLSCCRFLDD--NNIVTSSG-DTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDFNL 198
Query: 466 CASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCFSPNRYWLC-AAFGPSIKIWDLESK 293
SG D A LWD+ +G T H I A+CF PN +C + S +++DL +
Sbjct: 199 FISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRAD 258
Query: 292 EMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQVSISAR 128
+ + E I T S+A+S G+ LFAGY D VW S R
Sbjct: 259 QELICFSHESIICGIT---------SVAFSLSGRLLFAGYDDFNCNVWDSMKSER 304
Score = 42.3 bits (95), Expect = 0.002
Identities = 33/121 (27%), Positives = 54/121 (44%), Gaps = 7/121 (5%)
Frame = -2
Query: 643 SDWVSCVRFSPNHANPIIVSCGW-DRTVKVWHLT----NCKLKINHLGHSGYLNTVTVSP 479
S WV ++P+ N V+CG D +++L N K+ H+GYL+
Sbjct: 97 SSWVMTCAYAPS-GN--FVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLD 153
Query: 478 DGSLCASGGKDMKAMLWDLNDGKHLHT-LDHNDIITALCFSPN-RYWLCAAFGPSIKIWD 305
D ++ S G D LWD+ G+ + H +L SP+ ++ A S K+WD
Sbjct: 154 DNNIVTSSG-DTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWD 212
Query: 304 L 302
+
Sbjct: 213 V 213
>AB209283-1|BAD92520.1| 327|Homo sapiens guanine nucleotide-binding
protein, beta-3 subunit variant protein.
Length = 327
Score = 81.4 bits (192), Expect = 3e-15
Identities = 58/175 (33%), Positives = 85/175 (48%), Gaps = 2/175 (1%)
Frame = -2
Query: 646 HSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSL 467
H+ ++SC RF + N I+ S G D T +W + + K +GH+G ++ VSPD +L
Sbjct: 129 HTGYLSCCRFLDD--NNIVTSSG-DTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDFNL 185
Query: 466 CASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCFSPNRYWLC-AAFGPSIKIWDLESK 293
SG D A LWD+ +G T H I A+CF PN +C + S +++DL +
Sbjct: 186 FISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRAD 245
Query: 292 EMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQVSISAR 128
+ + E I T S+A+S G+ LFAGY D VW S R
Sbjct: 246 QELICFSHESIICGIT---------SVAFSLSGRLLFAGYDDFNCNVWDSMKSER 291
Score = 42.3 bits (95), Expect = 0.002
Identities = 33/121 (27%), Positives = 54/121 (44%), Gaps = 7/121 (5%)
Frame = -2
Query: 643 SDWVSCVRFSPNHANPIIVSCGW-DRTVKVWHLT----NCKLKINHLGHSGYLNTVTVSP 479
S WV ++P+ N V+CG D +++L N K+ H+GYL+
Sbjct: 84 SSWVMTCAYAPS-GN--FVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLD 140
Query: 478 DGSLCASGGKDMKAMLWDLNDGKHLHT-LDHNDIITALCFSPN-RYWLCAAFGPSIKIWD 305
D ++ S G D LWD+ G+ + H +L SP+ ++ A S K+WD
Sbjct: 141 DNNIVTSSG-DTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWD 199
Query: 304 L 302
+
Sbjct: 200 V 200
>AB053276-1|BAB69430.1| 348|Homo sapiens TUWD12 protein.
Length = 348
Score = 81.0 bits (191), Expect = 4e-15
Identities = 49/171 (28%), Positives = 84/171 (49%), Gaps = 2/171 (1%)
Frame = -2
Query: 646 HSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSL 467
H+ WV C +FSP+ +IVSC D+T+K+W TN + N G+ N V +P G+
Sbjct: 13 HTHWVRCAKFSPD--GRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVDFNPSGTC 70
Query: 466 CASGGKDMKAMLWDLNDGKHL-HTLDHNDIITALCFSPN-RYWLCAAFGPSIKIWDLESK 293
AS G D +WD+ K L H H+ + + F P+ Y + A+ ++KI DL
Sbjct: 71 IASAGSDQTVKVWDVRVNKLLQHYQVHSGGVNCISFHPSGNYLITASSDGTLKILDLLEG 130
Query: 292 EMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQVS 140
++ L+ T P ++++S G+ +G +D + +W+ +
Sbjct: 131 RLIYTLQ---------GHTGP--VFTVSFSKGGELFASGGADTQVLLWRTN 170
Score = 61.3 bits (142), Expect = 3e-09
Identities = 39/121 (32%), Positives = 62/121 (51%), Gaps = 2/121 (1%)
Frame = -2
Query: 715 SRDKTIKLWNTL-AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
S DKTIK+W+T +C D + + V F+P + I S G D+TVKVW +
Sbjct: 33 SEDKTIKIWDTTNKQCVNNFSDS--VGFANFVDFNP--SGTCIASAGSDQTVKVWDVRVN 88
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALCF 362
KL ++ HSG +N ++ P G+ + D + DL +G+ ++TL H + + F
Sbjct: 89 KLLQHYQVHSGGVNCISFHPSGNYLITASSDGTLKILDLLEGRLIYTLQGHTGPVFTVSF 148
Query: 361 S 359
S
Sbjct: 149 S 149
>AB053266-1|BAB69057.1| 348|Homo sapiens TUWD12 protein.
Length = 348
Score = 81.0 bits (191), Expect = 4e-15
Identities = 49/171 (28%), Positives = 84/171 (49%), Gaps = 2/171 (1%)
Frame = -2
Query: 646 HSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSL 467
H+ WV C +FSP+ +IVSC D+T+K+W TN + N G+ N V +P G+
Sbjct: 13 HTHWVRCAKFSPD--GRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVDFNPSGTC 70
Query: 466 CASGGKDMKAMLWDLNDGKHL-HTLDHNDIITALCFSPN-RYWLCAAFGPSIKIWDLESK 293
AS G D +WD+ K L H H+ + + F P+ Y + A+ ++KI DL
Sbjct: 71 IASAGSDQTVKVWDVRVNKLLQHYQVHSGGVNCISFHPSGNYLITASSDGTLKILDLLEG 130
Query: 292 EMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQVS 140
++ L+ T P ++++S G+ +G +D + +W+ +
Sbjct: 131 RLIYTLQ---------GHTGP--VFTVSFSKGGELFASGGADTQVLLWRTN 170
Score = 61.3 bits (142), Expect = 3e-09
Identities = 39/121 (32%), Positives = 62/121 (51%), Gaps = 2/121 (1%)
Frame = -2
Query: 715 SRDKTIKLWNTL-AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
S DKTIK+W+T +C D + + V F+P + I S G D+TVKVW +
Sbjct: 33 SEDKTIKIWDTTNKQCVNNFSDS--VGFANFVDFNP--SGTCIASAGSDQTVKVWDVRVN 88
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALCF 362
KL ++ HSG +N ++ P G+ + D + DL +G+ ++TL H + + F
Sbjct: 89 KLLQHYQVHSGGVNCISFHPSGNYLITASSDGTLKILDLLEGRLIYTLQGHTGPVFTVSF 148
Query: 361 S 359
S
Sbjct: 149 S 149
>AL354928-6|CAI39637.1| 314|Homo sapiens WD repeat domain 38
protein.
Length = 314
Score = 79.8 bits (188), Expect = 9e-15
Identities = 61/198 (30%), Positives = 91/198 (45%), Gaps = 2/198 (1%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
GS D + W T + + + GH+ V RFSP+ + S D TV++W +
Sbjct: 39 GSEDGCVYGWETRSG-QLLWRLGGHTGPVKFCRFSPD--GHLFASASCDCTVRLWDVARA 95
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCF 362
K GH + TV+ SPD ASGG D + MLWD+ G+ L L H D I + F
Sbjct: 96 KCLRVLKGHQRSVETVSFSPDSRQLASGGWDKRVMLWDVQSGQMLRLLVGHRDSIQSSDF 155
Query: 361 SPNRYWLC-AAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTL 185
SP L ++ ++ IWDL + P + +Q + C L +S G L
Sbjct: 156 SPTVNCLATGSWDSTVHIWDLRM------VTPAVSHQALEGHSANISC--LCYSASG-LL 206
Query: 184 FAGYSDNTIRVWQVSISA 131
+G D TI +W+ + S+
Sbjct: 207 ASGSWDKTIHIWKPTTSS 224
Score = 68.1 bits (159), Expect = 3e-11
Identities = 39/125 (31%), Positives = 60/125 (48%), Gaps = 3/125 (2%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQD--DGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 545
GS D T+ +W+ +GHS +SC+ +S A+ ++ S WD+T+ +W T
Sbjct: 165 GSWDSTVHIWDLRMVTPAVSHQALEGHSANISCLCYS---ASGLLASGSWDKTIHIWKPT 221
Query: 544 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDH-NDIITAL 368
L I GH ++ ++ SPD AS G +WD N GK L TL D+
Sbjct: 222 TSSLLIQLKGHVTWVKSIAFSPDELWLASAGYSRMVKVWDCNTGKCLETLKGVLDVAHTC 281
Query: 367 CFSPN 353
F+P+
Sbjct: 282 AFTPD 286
Score = 64.9 bits (151), Expect = 3e-10
Identities = 54/193 (27%), Positives = 88/193 (45%), Gaps = 5/193 (2%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
G DK + LW+ + + GH D + FSP N + + WD TV +W L
Sbjct: 123 GGWDKRVMLWDVQSGQMLRLLV-GHRDSIQSSDFSPT-VN-CLATGSWDSTVHIWDLRMV 179
Query: 538 KLKINHL---GHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITA 371
++H GHS ++ + S G L ASG D +W L L H + +
Sbjct: 180 TPAVSHQALEGHSANISCLCYSASG-LLASGSWDKTIHIWKPTTSSLLIQLKGHVTWVKS 238
Query: 370 LCFSPNRYWLCAA-FGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDG 194
+ FSP+ WL +A + +K+WD + + +E L+ +++ T C A++ DG
Sbjct: 239 IAFSPDELWLASAGYSRMVKVWDCNTGKCLETLK-GVLDVAHT-------C---AFTPDG 287
Query: 193 QTLFAGYSDNTIR 155
+ L +G +D T R
Sbjct: 288 KILVSGAADQTRR 300
Score = 60.1 bits (139), Expect = 8e-09
Identities = 40/156 (25%), Positives = 73/156 (46%), Gaps = 5/156 (3%)
Frame = -2
Query: 715 SRDKTIKLWNTL-AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
S D T++LW+ A+C ++ GH V V FSP+ + S GWD+ V +W + +
Sbjct: 82 SCDCTVRLWDVARAKCLRVLK--GHQRSVETVSFSPDSRQ--LASGGWDKRVMLWDVQSG 137
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLN----DGKHLHTLDHNDIITA 371
++ +GH + + SP + A+G D +WDL H H+ I+
Sbjct: 138 QMLRLLVGHRDSIQSSDFSPTVNCLATGSWDSTVHIWDLRMVTPAVSHQALEGHSANISC 197
Query: 370 LCFSPNRYWLCAAFGPSIKIWDLESKEMVEELRPEI 263
LC+S + ++ +I IW + ++ +L+ +
Sbjct: 198 LCYSASGLLASGSWDKTIHIWKPTTSSLLIQLKGHV 233
Score = 39.5 bits (88), Expect = 0.012
Identities = 29/126 (23%), Positives = 59/126 (46%), Gaps = 2/126 (1%)
Frame = -2
Query: 514 HSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCFSPNRY-WL 341
H G +N+ SPDG + +G +D W+ G+ L L H + FSP+ + +
Sbjct: 20 HGGEVNSSAFSPDGQMLLTGSEDGCVYGWETRSGQLLWRLGGHTGPVKFCRFSPDGHLFA 79
Query: 340 CAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNT 161
A+ ++++WD+ + + L+ ++ +T +++S D + L +G D
Sbjct: 80 SASCDCTVRLWDVARAKCLRVLK----GHQRSVET-------VSFSPDSRQLASGGWDKR 128
Query: 160 IRVWQV 143
+ +W V
Sbjct: 129 VMLWDV 134
>AL121990-7|CAI22015.1| 589|Homo sapiens TAF5-like RNA polymerase
II, p300/CBP-associated factor (PCAF)-associated facto
protein.
Length = 589
Score = 77.8 bits (183), Expect = 4e-14
Identities = 47/143 (32%), Positives = 72/143 (50%), Gaps = 2/143 (1%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
GS D+T +LW+ I GH V CV+F PN + + + D+TV++W
Sbjct: 402 GSHDRTARLWSFDRTYPLRIYA-GHLADVDCVKFHPN--SNYLATGSTDKTVRLWSAQQG 458
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCF 362
GH G + ++ SP+G AS G+D + LWDL G L H D IT+L F
Sbjct: 459 NSVRLFTGHRGPVLSLAFSPNGKYLASAGEDQRLKLWDLASGTLYKELRGHTDNITSLTF 518
Query: 361 SPNRYWLC-AAFGPSIKIWDLES 296
SP+ + A+ S+++WD+ +
Sbjct: 519 SPDSGLIASASMDNSVRVWDIRN 541
Score = 69.7 bits (163), Expect = 1e-11
Identities = 53/193 (27%), Positives = 81/193 (41%), Gaps = 2/193 (1%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK 536
S D +I+ W+ L T+ GH+ V + SP S DRT ++W
Sbjct: 361 SEDMSIRYWD-LGSFTNTVLYQGHAYPVWDLDISPYSL--YFASGSHDRTARLWSFDRTY 417
Query: 535 LKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALCFS 359
+ GH ++ V P+ + A+G D LW G + H + +L FS
Sbjct: 418 PLRIYAGHLADVDCVKFHPNSNYLATGSTDKTVRLWSAQQGNSVRLFTGHRGPVLSLAFS 477
Query: 358 PN-RYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLF 182
PN +Y A +K+WDL S + +ELR N T SL +S D +
Sbjct: 478 PNGKYLASAGEDQRLKLWDLASGTLYKELRGHTDNIT-----------SLTFSPDSGLIA 526
Query: 181 AGYSDNTIRVWQV 143
+ DN++RVW +
Sbjct: 527 SASMDNSVRVWDI 539
Score = 46.4 bits (105), Expect = 1e-04
Identities = 40/172 (23%), Positives = 73/172 (42%), Gaps = 2/172 (1%)
Frame = -2
Query: 649 GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGS 470
GH V RF + + ++SC D +++ W L + + + GH+ + + +SP
Sbjct: 340 GHCGPVYSTRFLADSSG--LLSCSEDMSIRYWDLGSFTNTVLYQGHAYPVWDLDISPYSL 397
Query: 469 LCASGGKDMKAMLWDLNDGKHLHT-LDHNDIITALCFSPN-RYWLCAAFGPSIKIWDLES 296
ASG D A LW + L H + + F PN Y + ++++W +
Sbjct: 398 YFASGSHDRTARLWSFDRTYPLRIYAGHLADVDCVKFHPNSNYLATGSTDKTVRLWSAQQ 457
Query: 295 KEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQVS 140
V + T P LSLA+S +G+ L + D +++W ++
Sbjct: 458 GNSV---------RLFTGHRGP--VLSLAFSPNGKYLASAGEDQRLKLWDLA 498
>AJ009770-1|CAA08816.1| 260|Homo sapiens putative transcription
factor protein.
Length = 260
Score = 77.8 bits (183), Expect = 4e-14
Identities = 47/143 (32%), Positives = 72/143 (50%), Gaps = 2/143 (1%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
GS D+T +LW+ I GH V CV+F PN + + + D+TV++W
Sbjct: 73 GSHDRTARLWSFDRTYPLRIYA-GHLADVDCVKFHPN--SNYLATGSTDKTVRLWSAQQG 129
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCF 362
GH G + ++ SP+G AS G+D + LWDL G L H D IT+L F
Sbjct: 130 NSVRLFTGHRGPVLSLAFSPNGKYLASAGEDQRLKLWDLASGTLYKELRGHTDNITSLTF 189
Query: 361 SPNRYWLC-AAFGPSIKIWDLES 296
SP+ + A+ S+++WD+ +
Sbjct: 190 SPDSGLIASASMDNSVRVWDIRN 212
Score = 69.7 bits (163), Expect = 1e-11
Identities = 53/193 (27%), Positives = 81/193 (41%), Gaps = 2/193 (1%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK 536
S D +I+ W+ L T+ GH+ V + SP S DRT ++W
Sbjct: 32 SEDMSIRYWD-LGSFTNTVLYQGHAYPVWDLDISPYSL--YFASGSHDRTARLWSFDRTY 88
Query: 535 LKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALCFS 359
+ GH ++ V P+ + A+G D LW G + H + +L FS
Sbjct: 89 PLRIYAGHLADVDCVKFHPNSNYLATGSTDKTVRLWSAQQGNSVRLFTGHRGPVLSLAFS 148
Query: 358 PN-RYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLF 182
PN +Y A +K+WDL S + +ELR N T SL +S D +
Sbjct: 149 PNGKYLASAGEDQRLKLWDLASGTLYKELRGHTDNIT-----------SLTFSPDSGLIA 197
Query: 181 AGYSDNTIRVWQV 143
+ DN++RVW +
Sbjct: 198 SASMDNSVRVWDI 210
Score = 46.4 bits (105), Expect = 1e-04
Identities = 40/172 (23%), Positives = 73/172 (42%), Gaps = 2/172 (1%)
Frame = -2
Query: 649 GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGS 470
GH V RF + + ++SC D +++ W L + + + GH+ + + +SP
Sbjct: 11 GHCGPVYSTRFLADSSG--LLSCSEDMSIRYWDLGSFTNTVLYQGHAYPVWDLDISPYSL 68
Query: 469 LCASGGKDMKAMLWDLNDGKHLHT-LDHNDIITALCFSPN-RYWLCAAFGPSIKIWDLES 296
ASG D A LW + L H + + F PN Y + ++++W +
Sbjct: 69 YFASGSHDRTARLWSFDRTYPLRIYAGHLADVDCVKFHPNSNYLATGSTDKTVRLWSAQQ 128
Query: 295 KEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQVS 140
V + T P LSLA+S +G+ L + D +++W ++
Sbjct: 129 GNSV---------RLFTGHRGP--VLSLAFSPNGKYLASAGEDQRLKLWDLA 169
>AF069736-1|AAC39906.1| 589|Homo sapiens PCAF associated factor 65
beta protein.
Length = 589
Score = 77.8 bits (183), Expect = 4e-14
Identities = 47/143 (32%), Positives = 72/143 (50%), Gaps = 2/143 (1%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
GS D+T +LW+ I GH V CV+F PN + + + D+TV++W
Sbjct: 402 GSHDRTARLWSFDRTYPLRIYA-GHLADVDCVKFHPN--SNYLATGSTDKTVRLWSAQQG 458
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCF 362
GH G + ++ SP+G AS G+D + LWDL G L H D IT+L F
Sbjct: 459 NSVRLFTGHRGPVLSLAFSPNGKYLASAGEDQRLKLWDLASGTLYKELRGHTDNITSLTF 518
Query: 361 SPNRYWLC-AAFGPSIKIWDLES 296
SP+ + A+ S+++WD+ +
Sbjct: 519 SPDSGLIASASMDNSVRVWDIRN 541
Score = 69.7 bits (163), Expect = 1e-11
Identities = 53/193 (27%), Positives = 81/193 (41%), Gaps = 2/193 (1%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK 536
S D +I+ W+ L T+ GH+ V + SP S DRT ++W
Sbjct: 361 SEDMSIRYWD-LGSFTNTVLYQGHAYPVWDLDISPYSL--YFASGSHDRTARLWSFDRTY 417
Query: 535 LKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALCFS 359
+ GH ++ V P+ + A+G D LW G + H + +L FS
Sbjct: 418 PLRIYAGHLADVDCVKFHPNSNYLATGSTDKTVRLWSAQQGNSVRLFTGHRGPVLSLAFS 477
Query: 358 PN-RYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLF 182
PN +Y A +K+WDL S + +ELR N T SL +S D +
Sbjct: 478 PNGKYLASAGEDQRLKLWDLASGTLYKELRGHTDNIT-----------SLTFSPDSGLIA 526
Query: 181 AGYSDNTIRVWQV 143
+ DN++RVW +
Sbjct: 527 SASMDNSVRVWDI 539
Score = 46.4 bits (105), Expect = 1e-04
Identities = 40/172 (23%), Positives = 73/172 (42%), Gaps = 2/172 (1%)
Frame = -2
Query: 649 GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGS 470
GH V RF + + ++SC D +++ W L + + + GH+ + + +SP
Sbjct: 340 GHCGPVYSTRFLADSSG--LLSCSEDMSIRYWDLGSFTNTVLYQGHAYPVWDLDISPYSL 397
Query: 469 LCASGGKDMKAMLWDLNDGKHLHT-LDHNDIITALCFSPN-RYWLCAAFGPSIKIWDLES 296
ASG D A LW + L H + + F PN Y + ++++W +
Sbjct: 398 YFASGSHDRTARLWSFDRTYPLRIYAGHLADVDCVKFHPNSNYLATGSTDKTVRLWSAQQ 457
Query: 295 KEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQVS 140
V + T P LSLA+S +G+ L + D +++W ++
Sbjct: 458 GNSV---------RLFTGHRGP--VLSLAFSPNGKYLASAGEDQRLKLWDLA 498
>M36429-1|AAA63264.1| 340|Homo sapiens protein ( Human transducin
beta-2 subunit mRNA, complete cds. ).
Length = 340
Score = 74.1 bits (174), Expect = 4e-13
Identities = 51/170 (30%), Positives = 82/170 (48%), Gaps = 3/170 (1%)
Frame = -2
Query: 649 GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGS 470
GH+ ++SC RF + N II S G D T +W + + + GHSG + +++++PDG
Sbjct: 141 GHTGYLSCCRFLDD--NQIITSSG-DTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGR 197
Query: 469 LCASGGKDMKAMLWDLNDGKHLHT-LDHNDIITALCFSPNRY-WLCAAFGPSIKIWDLES 296
SG D LWD+ D T + H I A+ F PN Y + + + +++DL +
Sbjct: 198 TFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRA 257
Query: 295 -KEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVW 149
+E++ II S+A+S G+ L AGY D +W
Sbjct: 258 DQELLMYSHDNII----------CGITSVAFSRSGRLLLAGYDDFNCNIW 297
Score = 33.5 bits (73), Expect = 0.78
Identities = 34/157 (21%), Positives = 67/157 (42%), Gaps = 6/157 (3%)
Frame = -2
Query: 595 IIVSCGWDRTVKVWH-LTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLN 419
++VS D + +W T K+ L S ++ T +P G+ A GG D ++ L
Sbjct: 69 LLVSASQDGKLIIWDSYTTNKVHAIPL-RSSWVMTCAYAPSGNFVACGGLDNICSIYSLK 127
Query: 418 --DGKHLHTLD---HNDIITALCFSPNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQ 254
+G + + H ++ F + + ++ + +WD+E+ + Q
Sbjct: 128 TREGNVRVSRELPGHTGYLSCCRFLDDNQIITSSGDTTCALWDIETGQ-----------Q 176
Query: 253 TQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQV 143
T +SL+ + DG+T +G D +I++W V
Sbjct: 177 TVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDV 213
>M16514-1|AAA03179.1| 340|Homo sapiens GNB2 protein.
Length = 340
Score = 74.1 bits (174), Expect = 4e-13
Identities = 51/170 (30%), Positives = 82/170 (48%), Gaps = 3/170 (1%)
Frame = -2
Query: 649 GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGS 470
GH+ ++SC RF + N II S G D T +W + + + GHSG + +++++PDG
Sbjct: 141 GHTGYLSCCRFLDD--NQIITSSG-DTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGR 197
Query: 469 LCASGGKDMKAMLWDLNDGKHLHT-LDHNDIITALCFSPNRY-WLCAAFGPSIKIWDLES 296
SG D LWD+ D T + H I A+ F PN Y + + + +++DL +
Sbjct: 198 TFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRA 257
Query: 295 -KEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVW 149
+E++ II S+A+S G+ L AGY D +W
Sbjct: 258 DQELLMYSHDNII----------CGITSVAFSRSGRLLLAGYDDFNCNIW 297
Score = 33.5 bits (73), Expect = 0.78
Identities = 34/157 (21%), Positives = 67/157 (42%), Gaps = 6/157 (3%)
Frame = -2
Query: 595 IIVSCGWDRTVKVWH-LTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLN 419
++VS D + +W T K+ L S ++ T +P G+ A GG D ++ L
Sbjct: 69 LLVSASQDGKLIIWDSYTTNKVHAIPL-RSSWVMTCAYAPSGNFVACGGLDNICSIYSLK 127
Query: 418 --DGKHLHTLD---HNDIITALCFSPNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQ 254
+G + + H ++ F + + ++ + +WD+E+ + Q
Sbjct: 128 TREGNVRVSRELPGHTGYLSCCRFLDDNQIITSSGDTTCALWDIETGQ-----------Q 176
Query: 253 TQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQV 143
T +SL+ + DG+T +G D +I++W V
Sbjct: 177 TVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDV 213
>CR541729-1|CAG46530.1| 340|Homo sapiens GNB2 protein.
Length = 340
Score = 74.1 bits (174), Expect = 4e-13
Identities = 51/170 (30%), Positives = 82/170 (48%), Gaps = 3/170 (1%)
Frame = -2
Query: 649 GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGS 470
GH+ ++SC RF + N II S G D T +W + + + GHSG + +++++PDG
Sbjct: 141 GHTGYLSCCRFLDD--NQIITSSG-DTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGR 197
Query: 469 LCASGGKDMKAMLWDLNDGKHLHT-LDHNDIITALCFSPNRY-WLCAAFGPSIKIWDLES 296
SG D LWD+ D T + H I A+ F PN Y + + + +++DL +
Sbjct: 198 TFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRA 257
Query: 295 -KEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVW 149
+E++ II S+A+S G+ L AGY D +W
Sbjct: 258 DQELLMYSHDNII----------CGITSVAFSRSGRLLLAGYDDFNCNIW 297
Score = 33.5 bits (73), Expect = 0.78
Identities = 34/157 (21%), Positives = 67/157 (42%), Gaps = 6/157 (3%)
Frame = -2
Query: 595 IIVSCGWDRTVKVWH-LTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLN 419
++VS D + +W T K+ L S ++ T +P G+ A GG D ++ L
Sbjct: 69 LLVSASQDGKLIIWDSYTTNKVHAIPL-RSSWVMTCAYAPSGNFVACGGLDNICSIYSLK 127
Query: 418 --DGKHLHTLD---HNDIITALCFSPNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQ 254
+G + + H ++ F + + ++ + +WD+E+ + Q
Sbjct: 128 TREGNVRVSRELPGHTGYLSCCRFLDDNQIITSSGDTTCALWDIETGQ-----------Q 176
Query: 253 TQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQV 143
T +SL+ + DG+T +G D +I++W V
Sbjct: 177 TVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDV 213
>BC068003-1|AAH68003.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2 protein.
Length = 340
Score = 74.1 bits (174), Expect = 4e-13
Identities = 51/170 (30%), Positives = 82/170 (48%), Gaps = 3/170 (1%)
Frame = -2
Query: 649 GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGS 470
GH+ ++SC RF + N II S G D T +W + + + GHSG + +++++PDG
Sbjct: 141 GHTGYLSCCRFLDD--NQIITSSG-DTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGR 197
Query: 469 LCASGGKDMKAMLWDLNDGKHLHT-LDHNDIITALCFSPNRY-WLCAAFGPSIKIWDLES 296
SG D LWD+ D T + H I A+ F PN Y + + + +++DL +
Sbjct: 198 TFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRA 257
Query: 295 -KEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVW 149
+E++ II S+A+S G+ L AGY D +W
Sbjct: 258 DQELLMYSHDNII----------CGITSVAFSRSGRLLLAGYDDFNCNIW 297
Score = 33.5 bits (73), Expect = 0.78
Identities = 34/157 (21%), Positives = 67/157 (42%), Gaps = 6/157 (3%)
Frame = -2
Query: 595 IIVSCGWDRTVKVWH-LTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLN 419
++VS D + +W T K+ L S ++ T +P G+ A GG D ++ L
Sbjct: 69 LLVSASQDGKLIIWDSYTTNKVHAIPL-RSSWVMTCAYAPSGNFVACGGLDNICSIYSLK 127
Query: 418 --DGKHLHTLD---HNDIITALCFSPNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQ 254
+G + + H ++ F + + ++ + +WD+E+ + Q
Sbjct: 128 TREGNVRVSRELPGHTGYLSCCRFLDDNQIITSSGDTTCALWDIETGQ-----------Q 176
Query: 253 TQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQV 143
T +SL+ + DG+T +G D +I++W V
Sbjct: 177 TVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDV 213
>BC012348-1|AAH12348.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2 protein.
Length = 340
Score = 74.1 bits (174), Expect = 4e-13
Identities = 51/170 (30%), Positives = 82/170 (48%), Gaps = 3/170 (1%)
Frame = -2
Query: 649 GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGS 470
GH+ ++SC RF + N II S G D T +W + + + GHSG + +++++PDG
Sbjct: 141 GHTGYLSCCRFLDD--NQIITSSG-DTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGR 197
Query: 469 LCASGGKDMKAMLWDLNDGKHLHT-LDHNDIITALCFSPNRY-WLCAAFGPSIKIWDLES 296
SG D LWD+ D T + H I A+ F PN Y + + + +++DL +
Sbjct: 198 TFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRA 257
Query: 295 -KEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVW 149
+E++ II S+A+S G+ L AGY D +W
Sbjct: 258 DQELLMYSHDNII----------CGITSVAFSRSGRLLLAGYDDFNCNIW 297
Score = 33.5 bits (73), Expect = 0.78
Identities = 34/157 (21%), Positives = 67/157 (42%), Gaps = 6/157 (3%)
Frame = -2
Query: 595 IIVSCGWDRTVKVWH-LTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLN 419
++VS D + +W T K+ L S ++ T +P G+ A GG D ++ L
Sbjct: 69 LLVSASQDGKLIIWDSYTTNKVHAIPL-RSSWVMTCAYAPSGNFVACGGLDNICSIYSLK 127
Query: 418 --DGKHLHTLD---HNDIITALCFSPNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQ 254
+G + + H ++ F + + ++ + +WD+E+ + Q
Sbjct: 128 TREGNVRVSRELPGHTGYLSCCRFLDDNQIITSSGDTTCALWDIETGQ-----------Q 176
Query: 253 TQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQV 143
T +SL+ + DG+T +G D +I++W V
Sbjct: 177 TVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDV 213
>BC010073-1|AAH10073.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2 protein.
Length = 340
Score = 74.1 bits (174), Expect = 4e-13
Identities = 51/170 (30%), Positives = 82/170 (48%), Gaps = 3/170 (1%)
Frame = -2
Query: 649 GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGS 470
GH+ ++SC RF + N II S G D T +W + + + GHSG + +++++PDG
Sbjct: 141 GHTGYLSCCRFLDD--NQIITSSG-DTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGR 197
Query: 469 LCASGGKDMKAMLWDLNDGKHLHT-LDHNDIITALCFSPNRY-WLCAAFGPSIKIWDLES 296
SG D LWD+ D T + H I A+ F PN Y + + + +++DL +
Sbjct: 198 TFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRA 257
Query: 295 -KEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVW 149
+E++ II S+A+S G+ L AGY D +W
Sbjct: 258 DQELLMYSHDNII----------CGITSVAFSRSGRLLLAGYDDFNCNIW 297
Score = 33.5 bits (73), Expect = 0.78
Identities = 34/157 (21%), Positives = 67/157 (42%), Gaps = 6/157 (3%)
Frame = -2
Query: 595 IIVSCGWDRTVKVWH-LTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLN 419
++VS D + +W T K+ L S ++ T +P G+ A GG D ++ L
Sbjct: 69 LLVSASQDGKLIIWDSYTTNKVHAIPL-RSSWVMTCAYAPSGNFVACGGLDNICSIYSLK 127
Query: 418 --DGKHLHTLD---HNDIITALCFSPNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQ 254
+G + + H ++ F + + ++ + +WD+E+ + Q
Sbjct: 128 TREGNVRVSRELPGHTGYLSCCRFLDDNQIITSSGDTTCALWDIETGQ-----------Q 176
Query: 253 TQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQV 143
T +SL+ + DG+T +G D +I++W V
Sbjct: 177 TVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDV 213
>AF501883-1|AAM15919.1| 340|Homo sapiens guanine nucleotide binding
protein beta 2 protein.
Length = 340
Score = 74.1 bits (174), Expect = 4e-13
Identities = 51/170 (30%), Positives = 82/170 (48%), Gaps = 3/170 (1%)
Frame = -2
Query: 649 GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGS 470
GH+ ++SC RF + N II S G D T +W + + + GHSG + +++++PDG
Sbjct: 141 GHTGYLSCCRFLDD--NQIITSSG-DTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGR 197
Query: 469 LCASGGKDMKAMLWDLNDGKHLHT-LDHNDIITALCFSPNRY-WLCAAFGPSIKIWDLES 296
SG D LWD+ D T + H I A+ F PN Y + + + +++DL +
Sbjct: 198 TFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRA 257
Query: 295 -KEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVW 149
+E++ II S+A+S G+ L AGY D +W
Sbjct: 258 DQELLMYSHDNII----------CGITSVAFSRSGRLLLAGYDDFNCNIW 297
Score = 33.5 bits (73), Expect = 0.78
Identities = 34/157 (21%), Positives = 67/157 (42%), Gaps = 6/157 (3%)
Frame = -2
Query: 595 IIVSCGWDRTVKVWH-LTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLN 419
++VS D + +W T K+ L S ++ T +P G+ A GG D ++ L
Sbjct: 69 LLVSASQDGKLIIWDSYTTNKVHAIPL-RSSWVMTCAYAPSGNFVACGGLDNICSIYSLK 127
Query: 418 --DGKHLHTLD---HNDIITALCFSPNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQ 254
+G + + H ++ F + + ++ + +WD+E+ + Q
Sbjct: 128 TREGNVRVSRELPGHTGYLSCCRFLDDNQIITSSGDTTCALWDIETGQ-----------Q 176
Query: 253 TQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQV 143
T +SL+ + DG+T +G D +I++W V
Sbjct: 177 TVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDV 213
>AF053356-4|AAC78794.1| 340|Homo sapiens GNB2 protein.
Length = 340
Score = 74.1 bits (174), Expect = 4e-13
Identities = 51/170 (30%), Positives = 82/170 (48%), Gaps = 3/170 (1%)
Frame = -2
Query: 649 GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGS 470
GH+ ++SC RF + N II S G D T +W + + + GHSG + +++++PDG
Sbjct: 141 GHTGYLSCCRFLDD--NQIITSSG-DTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGR 197
Query: 469 LCASGGKDMKAMLWDLNDGKHLHT-LDHNDIITALCFSPNRY-WLCAAFGPSIKIWDLES 296
SG D LWD+ D T + H I A+ F PN Y + + + +++DL +
Sbjct: 198 TFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRA 257
Query: 295 -KEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVW 149
+E++ II S+A+S G+ L AGY D +W
Sbjct: 258 DQELLMYSHDNII----------CGITSVAFSRSGRLLLAGYDDFNCNIW 297
Score = 33.5 bits (73), Expect = 0.78
Identities = 34/157 (21%), Positives = 67/157 (42%), Gaps = 6/157 (3%)
Frame = -2
Query: 595 IIVSCGWDRTVKVWH-LTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLN 419
++VS D + +W T K+ L S ++ T +P G+ A GG D ++ L
Sbjct: 69 LLVSASQDGKLIIWDSYTTNKVHAIPL-RSSWVMTCAYAPSGNFVACGGLDNICSIYSLK 127
Query: 418 --DGKHLHTLD---HNDIITALCFSPNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQ 254
+G + + H ++ F + + ++ + +WD+E+ + Q
Sbjct: 128 TREGNVRVSRELPGHTGYLSCCRFLDDNQIITSSGDTTCALWDIETGQ-----------Q 176
Query: 253 TQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQV 143
T +SL+ + DG+T +G D +I++W V
Sbjct: 177 TVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDV 213
>X95525-1|CAA64777.1| 799|Homo sapiens hTAFII100 protein.
Length = 799
Score = 73.3 bits (172), Expect = 8e-13
Identities = 59/191 (30%), Positives = 87/191 (45%), Gaps = 2/191 (1%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK 536
S D T++LW+ L + GH+ V +FSP VS G DR ++W + +
Sbjct: 562 SEDGTVRLWS-LQTFTCLVGYKGHNYPVWDTQFSPY--GYYFVSGGHDRVARLWATDHYQ 618
Query: 535 LKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALCFS 359
GH +N P+ + A+G D LWD+ +G + H I +L FS
Sbjct: 619 PLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFS 678
Query: 358 PN-RYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLF 182
PN R+ A + +WD+ MV EL+ T T C SL +S DG+ L
Sbjct: 679 PNGRFLATGATDGRVLLWDIGHGLMVGELK----GHTDTV------C-SLRFSRDGEILA 727
Query: 181 AGYSDNTIRVW 149
+G DNT+R+W
Sbjct: 728 SGSMDNTVRLW 738
Score = 71.3 bits (167), Expect = 3e-12
Identities = 43/140 (30%), Positives = 71/140 (50%), Gaps = 2/140 (1%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
G D+ +LW T I GH V+C RF PN + + + DRTV++W + N
Sbjct: 603 GGHDRVARLWATDHYQPLRIFA-GHLADVNCTRFHPN--SNYVATGSADRTVRLWDVLNG 659
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCF 362
GH G ++++T SP+G A+G D + +LWD+ G + L H D + +L F
Sbjct: 660 NCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRF 719
Query: 361 SPNRYWLCA-AFGPSIKIWD 305
S + L + + ++++WD
Sbjct: 720 SRDGEILASGSMDNTVRLWD 739
Score = 49.2 bits (112), Expect = 1e-05
Identities = 44/171 (25%), Positives = 71/171 (41%), Gaps = 2/171 (1%)
Frame = -2
Query: 649 GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGS 470
GHS V FSP+ ++S D TV++W L + + GH+ + SP G
Sbjct: 541 GHSGPVYGASFSPDRN--YLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGY 598
Query: 469 LCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCFSPN-RYWLCAAFGPSIKIWDLES 296
SGG D A LW + + L H + F PN Y + ++++WD+ +
Sbjct: 599 YFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLN 658
Query: 295 KEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQV 143
V + T P SL +S +G+ L G +D + +W +
Sbjct: 659 GNCV---------RIFTGHKGPIH--SLTFSPNGRFLATGATDGRVLLWDI 698
>U80191-1|AAC51215.1| 800|Homo sapiens TFIID subunit TAFII100
protein.
Length = 800
Score = 73.3 bits (172), Expect = 8e-13
Identities = 59/191 (30%), Positives = 87/191 (45%), Gaps = 2/191 (1%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK 536
S D T++LW+ L + GH+ V +FSP VS G DR ++W + +
Sbjct: 562 SEDGTVRLWS-LQTFTCLVGYKGHNYPVWDTQFSPY--GYYFVSGGHDRVARLWATDHYQ 618
Query: 535 LKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALCFS 359
GH +N P+ + A+G D LWD+ +G + H I +L FS
Sbjct: 619 PLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFS 678
Query: 358 PN-RYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLF 182
PN R+ A + +WD+ MV EL+ T T C SL +S DG+ L
Sbjct: 679 PNGRFLATGATDGRVLLWDIGHGLMVGELK----GHTDTV------C-SLRFSRDGEILA 727
Query: 181 AGYSDNTIRVW 149
+G DNT+R+W
Sbjct: 728 SGSMDNTVRLW 738
Score = 71.3 bits (167), Expect = 3e-12
Identities = 43/140 (30%), Positives = 71/140 (50%), Gaps = 2/140 (1%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
G D+ +LW T I GH V+C RF PN + + + DRTV++W + N
Sbjct: 603 GGHDRVARLWATDHYQPLRIFA-GHLADVNCTRFHPN--SNYVATGSADRTVRLWDVLNG 659
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCF 362
GH G ++++T SP+G A+G D + +LWD+ G + L H D + +L F
Sbjct: 660 NCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRF 719
Query: 361 SPNRYWLCA-AFGPSIKIWD 305
S + L + + ++++WD
Sbjct: 720 SRDGEILASGSMDNTVRLWD 739
Score = 49.2 bits (112), Expect = 1e-05
Identities = 44/171 (25%), Positives = 71/171 (41%), Gaps = 2/171 (1%)
Frame = -2
Query: 649 GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGS 470
GHS V FSP+ ++S D TV++W L + + GH+ + SP G
Sbjct: 541 GHSGPVYGASFSPDRN--YLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGY 598
Query: 469 LCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCFSPN-RYWLCAAFGPSIKIWDLES 296
SGG D A LW + + L H + F PN Y + ++++WD+ +
Sbjct: 599 YFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLN 658
Query: 295 KEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQV 143
V + T P SL +S +G+ L G +D + +W +
Sbjct: 659 GNCV---------RIFTGHKGPIH--SLTFSPNGRFLATGATDGRVLLWDI 698
>U75309-1|AAC50902.1| 801|Homo sapiens TBP-associated factor protein.
Length = 801
Score = 73.3 bits (172), Expect = 8e-13
Identities = 59/191 (30%), Positives = 87/191 (45%), Gaps = 2/191 (1%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK 536
S D T++LW+ L + GH+ V +FSP VS G DR ++W + +
Sbjct: 563 SEDGTVRLWS-LQTFTCLVGYKGHNYPVWDTQFSPY--GYYFVSGGHDRVARLWATDHYQ 619
Query: 535 LKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALCFS 359
GH +N P+ + A+G D LWD+ +G + H I +L FS
Sbjct: 620 PLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFS 679
Query: 358 PN-RYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLF 182
PN R+ A + +WD+ MV EL+ T T C SL +S DG+ L
Sbjct: 680 PNGRFLATGATDGRVLLWDIGHGLMVGELK----GHTDTV------C-SLRFSRDGEILA 728
Query: 181 AGYSDNTIRVW 149
+G DNT+R+W
Sbjct: 729 SGSMDNTVRLW 739
Score = 71.3 bits (167), Expect = 3e-12
Identities = 43/140 (30%), Positives = 71/140 (50%), Gaps = 2/140 (1%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
G D+ +LW T I GH V+C RF PN + + + DRTV++W + N
Sbjct: 604 GGHDRVARLWATDHYQPLRIFA-GHLADVNCTRFHPN--SNYVATGSADRTVRLWDVLNG 660
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCF 362
GH G ++++T SP+G A+G D + +LWD+ G + L H D + +L F
Sbjct: 661 NCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRF 720
Query: 361 SPNRYWLCA-AFGPSIKIWD 305
S + L + + ++++WD
Sbjct: 721 SRDGEILASGSMDNTVRLWD 740
Score = 49.2 bits (112), Expect = 1e-05
Identities = 44/171 (25%), Positives = 71/171 (41%), Gaps = 2/171 (1%)
Frame = -2
Query: 649 GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGS 470
GHS V FSP+ ++S D TV++W L + + GH+ + SP G
Sbjct: 542 GHSGPVYGASFSPDRN--YLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGY 599
Query: 469 LCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCFSPN-RYWLCAAFGPSIKIWDLES 296
SGG D A LW + + L H + F PN Y + ++++WD+ +
Sbjct: 600 YFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLN 659
Query: 295 KEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQV 143
V + T P SL +S +G+ L G +D + +W +
Sbjct: 660 GNCV---------RIFTGHKGPIH--SLTFSPNGRFLATGATDGRVLLWDI 699
>BC052268-1|AAH52268.2| 800|Homo sapiens TAF5 RNA polymerase II, TATA
box binding protein (TBP)-associated factor, 100kD
protein.
Length = 800
Score = 73.3 bits (172), Expect = 8e-13
Identities = 59/191 (30%), Positives = 87/191 (45%), Gaps = 2/191 (1%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK 536
S D T++LW+ L + GH+ V +FSP VS G DR ++W + +
Sbjct: 562 SEDGTVRLWS-LQTFTCLVGYKGHNYPVWDTQFSPY--GYYFVSGGHDRVARLWATDHYQ 618
Query: 535 LKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALCFS 359
GH +N P+ + A+G D LWD+ +G + H I +L FS
Sbjct: 619 PLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFS 678
Query: 358 PN-RYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLF 182
PN R+ A + +WD+ MV EL+ T T C SL +S DG+ L
Sbjct: 679 PNGRFLATGATDGRVLLWDIGHGLMVGELK----GHTDTV------C-SLRFSRDGEILA 727
Query: 181 AGYSDNTIRVW 149
+G DNT+R+W
Sbjct: 728 SGSMDNTVRLW 738
Score = 71.3 bits (167), Expect = 3e-12
Identities = 43/140 (30%), Positives = 71/140 (50%), Gaps = 2/140 (1%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
G D+ +LW T I GH V+C RF PN + + + DRTV++W + N
Sbjct: 603 GGHDRVARLWATDHYQPLRIFA-GHLADVNCTRFHPN--SNYVATGSADRTVRLWDVLNG 659
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCF 362
GH G ++++T SP+G A+G D + +LWD+ G + L H D + +L F
Sbjct: 660 NCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRF 719
Query: 361 SPNRYWLCA-AFGPSIKIWD 305
S + L + + ++++WD
Sbjct: 720 SRDGEILASGSMDNTVRLWD 739
Score = 49.2 bits (112), Expect = 1e-05
Identities = 44/171 (25%), Positives = 71/171 (41%), Gaps = 2/171 (1%)
Frame = -2
Query: 649 GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGS 470
GHS V FSP+ ++S D TV++W L + + GH+ + SP G
Sbjct: 541 GHSGPVYGASFSPDRN--YLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGY 598
Query: 469 LCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCFSPN-RYWLCAAFGPSIKIWDLES 296
SGG D A LW + + L H + F PN Y + ++++WD+ +
Sbjct: 599 YFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLN 658
Query: 295 KEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQV 143
V + T P SL +S +G+ L G +D + +W +
Sbjct: 659 GNCV---------RIFTGHKGPIH--SLTFSPNGRFLATGATDGRVLLWDI 698
>AL591408-4|CAI16747.1| 800|Homo sapiens TAF5 RNA polymerase II, TATA
box binding protein (TBP)-associated factor, 100kD
protein.
Length = 800
Score = 73.3 bits (172), Expect = 8e-13
Identities = 59/191 (30%), Positives = 87/191 (45%), Gaps = 2/191 (1%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK 536
S D T++LW+ L + GH+ V +FSP VS G DR ++W + +
Sbjct: 562 SEDGTVRLWS-LQTFTCLVGYKGHNYPVWDTQFSPY--GYYFVSGGHDRVARLWATDHYQ 618
Query: 535 LKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALCFS 359
GH +N P+ + A+G D LWD+ +G + H I +L FS
Sbjct: 619 PLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFS 678
Query: 358 PN-RYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLF 182
PN R+ A + +WD+ MV EL+ T T C SL +S DG+ L
Sbjct: 679 PNGRFLATGATDGRVLLWDIGHGLMVGELK----GHTDTV------C-SLRFSRDGEILA 727
Query: 181 AGYSDNTIRVW 149
+G DNT+R+W
Sbjct: 728 SGSMDNTVRLW 738
Score = 71.3 bits (167), Expect = 3e-12
Identities = 43/140 (30%), Positives = 71/140 (50%), Gaps = 2/140 (1%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
G D+ +LW T I GH V+C RF PN + + + DRTV++W + N
Sbjct: 603 GGHDRVARLWATDHYQPLRIFA-GHLADVNCTRFHPN--SNYVATGSADRTVRLWDVLNG 659
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCF 362
GH G ++++T SP+G A+G D + +LWD+ G + L H D + +L F
Sbjct: 660 NCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRF 719
Query: 361 SPNRYWLCA-AFGPSIKIWD 305
S + L + + ++++WD
Sbjct: 720 SRDGEILASGSMDNTVRLWD 739
Score = 49.2 bits (112), Expect = 1e-05
Identities = 44/171 (25%), Positives = 71/171 (41%), Gaps = 2/171 (1%)
Frame = -2
Query: 649 GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGS 470
GHS V FSP+ ++S D TV++W L + + GH+ + SP G
Sbjct: 541 GHSGPVYGASFSPDRN--YLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGY 598
Query: 469 LCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCFSPN-RYWLCAAFGPSIKIWDLES 296
SGG D A LW + + L H + F PN Y + ++++WD+ +
Sbjct: 599 YFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLN 658
Query: 295 KEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQV 143
V + T P SL +S +G+ L G +D + +W +
Sbjct: 659 GNCV---------RIFTGHKGPIH--SLTFSPNGRFLATGATDGRVLLWDI 698
>AK223615-1|BAD97335.1| 803|Homo sapiens Transcription initiation
factor TFIID subunit 5 variant protein.
Length = 803
Score = 73.3 bits (172), Expect = 8e-13
Identities = 59/191 (30%), Positives = 87/191 (45%), Gaps = 2/191 (1%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK 536
S D T++LW+ L + GH+ V +FSP VS G DR ++W + +
Sbjct: 565 SEDGTVRLWS-LQTFTCLVGYKGHNYPVWDTQFSPY--GYYFVSGGHDRVARLWATDHYQ 621
Query: 535 LKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALCFS 359
GH +N P+ + A+G D LWD+ +G + H I +L FS
Sbjct: 622 PLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFS 681
Query: 358 PN-RYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLF 182
PN R+ A + +WD+ MV EL+ T T C SL +S DG+ L
Sbjct: 682 PNGRFLATGATDGRVLLWDIGHGLMVGELK----GHTDTV------C-SLRFSRDGEILA 730
Query: 181 AGYSDNTIRVW 149
+G DNT+R+W
Sbjct: 731 SGSMDNTVRLW 741
Score = 71.3 bits (167), Expect = 3e-12
Identities = 43/140 (30%), Positives = 71/140 (50%), Gaps = 2/140 (1%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
G D+ +LW T I GH V+C RF PN + + + DRTV++W + N
Sbjct: 606 GGHDRVARLWATDHYQPLRIFA-GHLADVNCTRFHPN--SNYVATGSADRTVRLWDVLNG 662
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCF 362
GH G ++++T SP+G A+G D + +LWD+ G + L H D + +L F
Sbjct: 663 NCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRF 722
Query: 361 SPNRYWLCA-AFGPSIKIWD 305
S + L + + ++++WD
Sbjct: 723 SRDGEILASGSMDNTVRLWD 742
Score = 49.2 bits (112), Expect = 1e-05
Identities = 44/171 (25%), Positives = 71/171 (41%), Gaps = 2/171 (1%)
Frame = -2
Query: 649 GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGS 470
GHS V FSP+ ++S D TV++W L + + GH+ + SP G
Sbjct: 544 GHSGPVYGASFSPDRN--YLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGY 601
Query: 469 LCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCFSPN-RYWLCAAFGPSIKIWDLES 296
SGG D A LW + + L H + F PN Y + ++++WD+ +
Sbjct: 602 YFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLN 661
Query: 295 KEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQV 143
V + T P SL +S +G+ L G +D + +W +
Sbjct: 662 GNCV---------RIFTGHKGPIH--SLTFSPNGRFLATGATDGRVLLWDI 701
>X04526-2|CAA28207.1| 340|Homo sapiens protein ( Human liver mRNA
for beta-subunit signal transducing proteins Gs/Gi
(beta-G). ).
Length = 340
Score = 72.9 bits (171), Expect = 1e-12
Identities = 50/171 (29%), Positives = 81/171 (47%), Gaps = 4/171 (2%)
Frame = -2
Query: 649 GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGS 470
GH+ ++SC RF + N I+ S G D T +W + + GH+G + +++++PD
Sbjct: 141 GHTGYLSCCRFLDD--NQIVTSSG-DTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTR 197
Query: 469 LCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCFSPN-RYWLCAAFGPSIKIWDLES 296
L SG D A LWD+ +G T H I A+CF PN + + + +++DL +
Sbjct: 198 LFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRA 257
Query: 295 KEMVEELRPEIINQTQTSKTDPPQC--LSLAWSTDGQTLFAGYSDNTIRVW 149
+ + T D C S+++S G+ L AGY D VW
Sbjct: 258 DQ-----------ELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVW 297
Score = 55.6 bits (128), Expect = 2e-07
Identities = 38/141 (26%), Positives = 65/141 (46%), Gaps = 4/141 (2%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK 536
S D T LW+ + + T GH+ V + +P+ + VS D + K+W +
Sbjct: 161 SGDTTCALWD-IETGQQTTTFTGHTGDVMSLSLAPD--TRLFVSGACDASAKLWDVREGM 217
Query: 535 LKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDI---ITALC 365
+ GH +N + P+G+ A+G D L+DL + L T H++I IT++
Sbjct: 218 CRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVS 277
Query: 364 FSPNRYWLCAAFGP-SIKIWD 305
FS + L A + + +WD
Sbjct: 278 FSKSGRLLLAGYDDFNCNVWD 298
Score = 47.2 bits (107), Expect = 6e-05
Identities = 34/121 (28%), Positives = 56/121 (46%), Gaps = 7/121 (5%)
Frame = -2
Query: 643 SDWVSCVRFSPNHANPIIVSCGW-DRTVKVWHLT----NCKLKINHLGHSGYLNTVTVSP 479
S WV ++P+ N V+CG D +++L N ++ GH+GYL+
Sbjct: 97 SSWVMTCAYAPS-GN--YVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLD 153
Query: 478 DGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCFSPN-RYWLCAAFGPSIKIWD 305
D + S G D LWD+ G+ T H + +L +P+ R ++ A S K+WD
Sbjct: 154 DNQIVTSSG-DTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWD 212
Query: 304 L 302
+
Sbjct: 213 V 213
>M36430-1|AAA63265.1| 247|Homo sapiens protein ( Human transducin
beta-1 subunit mRNA, 3' end. ).
Length = 247
Score = 72.9 bits (171), Expect = 1e-12
Identities = 50/171 (29%), Positives = 81/171 (47%), Gaps = 4/171 (2%)
Frame = -2
Query: 649 GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGS 470
GH+ ++SC RF + N I+ S G D T +W + + GH+G + +++++PD
Sbjct: 48 GHTGYLSCCRFLDD--NQIVTSSG-DTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTR 104
Query: 469 LCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCFSPN-RYWLCAAFGPSIKIWDLES 296
L SG D A LWD+ +G T H I A+CF PN + + + +++DL +
Sbjct: 105 LFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRA 164
Query: 295 KEMVEELRPEIINQTQTSKTDPPQC--LSLAWSTDGQTLFAGYSDNTIRVW 149
+ + T D C S+++S G+ L AGY D VW
Sbjct: 165 DQ-----------ELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVW 204
Score = 55.6 bits (128), Expect = 2e-07
Identities = 38/141 (26%), Positives = 65/141 (46%), Gaps = 4/141 (2%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK 536
S D T LW+ + + T GH+ V + +P+ + VS D + K+W +
Sbjct: 68 SGDTTCALWD-IETGQQTTTFTGHTGDVMSLSLAPD--TRLFVSGACDASAKLWDVREGM 124
Query: 535 LKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDI---ITALC 365
+ GH +N + P+G+ A+G D L+DL + L T H++I IT++
Sbjct: 125 CRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVS 184
Query: 364 FSPNRYWLCAAFGP-SIKIWD 305
FS + L A + + +WD
Sbjct: 185 FSKSGRLLLAGYDDFNCNVWD 205
Score = 47.2 bits (107), Expect = 6e-05
Identities = 34/121 (28%), Positives = 56/121 (46%), Gaps = 7/121 (5%)
Frame = -2
Query: 643 SDWVSCVRFSPNHANPIIVSCGW-DRTVKVWHLT----NCKLKINHLGHSGYLNTVTVSP 479
S WV ++P+ N V+CG D +++L N ++ GH+GYL+
Sbjct: 4 SSWVMTCAYAPS-GN--YVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLD 60
Query: 478 DGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCFSPN-RYWLCAAFGPSIKIWD 305
D + S G D LWD+ G+ T H + +L +P+ R ++ A S K+WD
Sbjct: 61 DNQIVTSSG-DTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWD 119
Query: 304 L 302
+
Sbjct: 120 V 120
>CR456784-1|CAG33065.1| 340|Homo sapiens GNB1 protein.
Length = 340
Score = 72.9 bits (171), Expect = 1e-12
Identities = 50/171 (29%), Positives = 81/171 (47%), Gaps = 4/171 (2%)
Frame = -2
Query: 649 GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGS 470
GH+ ++SC RF + N I+ S G D T +W + + GH+G + +++++PD
Sbjct: 141 GHTGYLSCCRFLDD--NQIVTSSG-DTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTR 197
Query: 469 LCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCFSPN-RYWLCAAFGPSIKIWDLES 296
L SG D A LWD+ +G T H I A+CF PN + + + +++DL +
Sbjct: 198 LFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRA 257
Query: 295 KEMVEELRPEIINQTQTSKTDPPQC--LSLAWSTDGQTLFAGYSDNTIRVW 149
+ + T D C S+++S G+ L AGY D VW
Sbjct: 258 DQ-----------ELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVW 297
Score = 55.6 bits (128), Expect = 2e-07
Identities = 38/141 (26%), Positives = 65/141 (46%), Gaps = 4/141 (2%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK 536
S D T LW+ + + T GH+ V + +P+ + VS D + K+W +
Sbjct: 161 SGDTTCALWD-IETGQQTTTFTGHTGDVMSLSLAPD--TRLFVSGACDASAKLWDVREGM 217
Query: 535 LKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDI---ITALC 365
+ GH +N + P+G+ A+G D L+DL + L T H++I IT++
Sbjct: 218 CRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVS 277
Query: 364 FSPNRYWLCAAFGP-SIKIWD 305
FS + L A + + +WD
Sbjct: 278 FSKSGRLLLAGYDDFNCNVWD 298
Score = 47.2 bits (107), Expect = 6e-05
Identities = 34/121 (28%), Positives = 56/121 (46%), Gaps = 7/121 (5%)
Frame = -2
Query: 643 SDWVSCVRFSPNHANPIIVSCGW-DRTVKVWHLT----NCKLKINHLGHSGYLNTVTVSP 479
S WV ++P+ N V+CG D +++L N ++ GH+GYL+
Sbjct: 97 SSWVMTCAYAPS-GN--YVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLD 153
Query: 478 DGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCFSPN-RYWLCAAFGPSIKIWD 305
D + S G D LWD+ G+ T H + +L +P+ R ++ A S K+WD
Sbjct: 154 DNQIVTSSG-DTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWD 212
Query: 304 L 302
+
Sbjct: 213 V 213
>BT007305-1|AAP35969.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 1 protein.
Length = 340
Score = 72.9 bits (171), Expect = 1e-12
Identities = 50/171 (29%), Positives = 81/171 (47%), Gaps = 4/171 (2%)
Frame = -2
Query: 649 GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGS 470
GH+ ++SC RF + N I+ S G D T +W + + GH+G + +++++PD
Sbjct: 141 GHTGYLSCCRFLDD--NQIVTSSG-DTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTR 197
Query: 469 LCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCFSPN-RYWLCAAFGPSIKIWDLES 296
L SG D A LWD+ +G T H I A+CF PN + + + +++DL +
Sbjct: 198 LFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRA 257
Query: 295 KEMVEELRPEIINQTQTSKTDPPQC--LSLAWSTDGQTLFAGYSDNTIRVW 149
+ + T D C S+++S G+ L AGY D VW
Sbjct: 258 DQ-----------ELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVW 297
Score = 55.6 bits (128), Expect = 2e-07
Identities = 38/141 (26%), Positives = 65/141 (46%), Gaps = 4/141 (2%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK 536
S D T LW+ + + T GH+ V + +P+ + VS D + K+W +
Sbjct: 161 SGDTTCALWD-IETGQQTTTFTGHTGDVMSLSLAPD--TRLFVSGACDASAKLWDVREGM 217
Query: 535 LKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDI---ITALC 365
+ GH +N + P+G+ A+G D L+DL + L T H++I IT++
Sbjct: 218 CRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVS 277
Query: 364 FSPNRYWLCAAFGP-SIKIWD 305
FS + L A + + +WD
Sbjct: 278 FSKSGRLLLAGYDDFNCNVWD 298
Score = 47.2 bits (107), Expect = 6e-05
Identities = 34/121 (28%), Positives = 56/121 (46%), Gaps = 7/121 (5%)
Frame = -2
Query: 643 SDWVSCVRFSPNHANPIIVSCGW-DRTVKVWHLT----NCKLKINHLGHSGYLNTVTVSP 479
S WV ++P+ N V+CG D +++L N ++ GH+GYL+
Sbjct: 97 SSWVMTCAYAPS-GN--YVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLD 153
Query: 478 DGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCFSPN-RYWLCAAFGPSIKIWD 305
D + S G D LWD+ G+ T H + +L +P+ R ++ A S K+WD
Sbjct: 154 DNQIVTSSG-DTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWD 212
Query: 304 L 302
+
Sbjct: 213 V 213
>BC114618-1|AAI14619.1| 332|Homo sapiens GNB1 protein protein.
Length = 332
Score = 72.9 bits (171), Expect = 1e-12
Identities = 50/171 (29%), Positives = 81/171 (47%), Gaps = 4/171 (2%)
Frame = -2
Query: 649 GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGS 470
GH+ ++SC RF + N I+ S G D T +W + + GH+G + +++++PD
Sbjct: 141 GHTGYLSCCRFLDD--NQIVTSSG-DTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTR 197
Query: 469 LCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCFSPN-RYWLCAAFGPSIKIWDLES 296
L SG D A LWD+ +G T H I A+CF PN + + + +++DL +
Sbjct: 198 LFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRA 257
Query: 295 KEMVEELRPEIINQTQTSKTDPPQC--LSLAWSTDGQTLFAGYSDNTIRVW 149
+ + T D C S+++S G+ L AGY D VW
Sbjct: 258 DQ-----------ELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVW 297
Score = 55.6 bits (128), Expect = 2e-07
Identities = 38/141 (26%), Positives = 65/141 (46%), Gaps = 4/141 (2%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK 536
S D T LW+ + + T GH+ V + +P+ + VS D + K+W +
Sbjct: 161 SGDTTCALWD-IETGQQTTTFTGHTGDVMSLSLAPD--TRLFVSGACDASAKLWDVREGM 217
Query: 535 LKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDI---ITALC 365
+ GH +N + P+G+ A+G D L+DL + L T H++I IT++
Sbjct: 218 CRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVS 277
Query: 364 FSPNRYWLCAAFGP-SIKIWD 305
FS + L A + + +WD
Sbjct: 278 FSKSGRLLLAGYDDFNCNVWD 298
Score = 47.2 bits (107), Expect = 6e-05
Identities = 34/121 (28%), Positives = 56/121 (46%), Gaps = 7/121 (5%)
Frame = -2
Query: 643 SDWVSCVRFSPNHANPIIVSCGW-DRTVKVWHLT----NCKLKINHLGHSGYLNTVTVSP 479
S WV ++P+ N V+CG D +++L N ++ GH+GYL+
Sbjct: 97 SSWVMTCAYAPS-GN--YVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLD 153
Query: 478 DGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCFSPN-RYWLCAAFGPSIKIWD 305
D + S G D LWD+ G+ T H + +L +P+ R ++ A S K+WD
Sbjct: 154 DNQIVTSSG-DTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWD 212
Query: 304 L 302
+
Sbjct: 213 V 213
>BC008991-1|AAH08991.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 1 protein.
Length = 340
Score = 72.9 bits (171), Expect = 1e-12
Identities = 50/171 (29%), Positives = 81/171 (47%), Gaps = 4/171 (2%)
Frame = -2
Query: 649 GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGS 470
GH+ ++SC RF + N I+ S G D T +W + + GH+G + +++++PD
Sbjct: 141 GHTGYLSCCRFLDD--NQIVTSSG-DTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTR 197
Query: 469 LCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCFSPN-RYWLCAAFGPSIKIWDLES 296
L SG D A LWD+ +G T H I A+CF PN + + + +++DL +
Sbjct: 198 LFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRA 257
Query: 295 KEMVEELRPEIINQTQTSKTDPPQC--LSLAWSTDGQTLFAGYSDNTIRVW 149
+ + T D C S+++S G+ L AGY D VW
Sbjct: 258 DQ-----------ELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVW 297
Score = 55.6 bits (128), Expect = 2e-07
Identities = 38/141 (26%), Positives = 65/141 (46%), Gaps = 4/141 (2%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK 536
S D T LW+ + + T GH+ V + +P+ + VS D + K+W +
Sbjct: 161 SGDTTCALWD-IETGQQTTTFTGHTGDVMSLSLAPD--TRLFVSGACDASAKLWDVREGM 217
Query: 535 LKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDI---ITALC 365
+ GH +N + P+G+ A+G D L+DL + L T H++I IT++
Sbjct: 218 CRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVS 277
Query: 364 FSPNRYWLCAAFGP-SIKIWD 305
FS + L A + + +WD
Sbjct: 278 FSKSGRLLLAGYDDFNCNVWD 298
Score = 47.2 bits (107), Expect = 6e-05
Identities = 34/121 (28%), Positives = 56/121 (46%), Gaps = 7/121 (5%)
Frame = -2
Query: 643 SDWVSCVRFSPNHANPIIVSCGW-DRTVKVWHLT----NCKLKINHLGHSGYLNTVTVSP 479
S WV ++P+ N V+CG D +++L N ++ GH+GYL+
Sbjct: 97 SSWVMTCAYAPS-GN--YVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLD 153
Query: 478 DGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCFSPN-RYWLCAAFGPSIKIWD 305
D + S G D LWD+ G+ T H + +L +P+ R ++ A S K+WD
Sbjct: 154 DNQIVTSSG-DTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWD 212
Query: 304 L 302
+
Sbjct: 213 V 213
>BC005888-1|AAH05888.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 1 protein.
Length = 340
Score = 72.9 bits (171), Expect = 1e-12
Identities = 50/171 (29%), Positives = 81/171 (47%), Gaps = 4/171 (2%)
Frame = -2
Query: 649 GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGS 470
GH+ ++SC RF + N I+ S G D T +W + + GH+G + +++++PD
Sbjct: 141 GHTGYLSCCRFLDD--NQIVTSSG-DTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTR 197
Query: 469 LCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCFSPN-RYWLCAAFGPSIKIWDLES 296
L SG D A LWD+ +G T H I A+CF PN + + + +++DL +
Sbjct: 198 LFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRA 257
Query: 295 KEMVEELRPEIINQTQTSKTDPPQC--LSLAWSTDGQTLFAGYSDNTIRVW 149
+ + T D C S+++S G+ L AGY D VW
Sbjct: 258 DQ-----------ELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVW 297
Score = 55.6 bits (128), Expect = 2e-07
Identities = 38/141 (26%), Positives = 65/141 (46%), Gaps = 4/141 (2%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK 536
S D T LW+ + + T GH+ V + +P+ + VS D + K+W +
Sbjct: 161 SGDTTCALWD-IETGQQTTTFTGHTGDVMSLSLAPD--TRLFVSGACDASAKLWDVREGM 217
Query: 535 LKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDI---ITALC 365
+ GH +N + P+G+ A+G D L+DL + L T H++I IT++
Sbjct: 218 CRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVS 277
Query: 364 FSPNRYWLCAAFGP-SIKIWD 305
FS + L A + + +WD
Sbjct: 278 FSKSGRLLLAGYDDFNCNVWD 298
Score = 47.2 bits (107), Expect = 6e-05
Identities = 34/121 (28%), Positives = 56/121 (46%), Gaps = 7/121 (5%)
Frame = -2
Query: 643 SDWVSCVRFSPNHANPIIVSCGW-DRTVKVWHLT----NCKLKINHLGHSGYLNTVTVSP 479
S WV ++P+ N V+CG D +++L N ++ GH+GYL+
Sbjct: 97 SSWVMTCAYAPS-GN--YVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLD 153
Query: 478 DGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCFSPN-RYWLCAAFGPSIKIWD 305
D + S G D LWD+ G+ T H + +L +P+ R ++ A S K+WD
Sbjct: 154 DNQIVTSSG-DTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWD 212
Query: 304 L 302
+
Sbjct: 213 V 213
>BC004186-1|AAH04186.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 1 protein.
Length = 340
Score = 72.9 bits (171), Expect = 1e-12
Identities = 50/171 (29%), Positives = 81/171 (47%), Gaps = 4/171 (2%)
Frame = -2
Query: 649 GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGS 470
GH+ ++SC RF + N I+ S G D T +W + + GH+G + +++++PD
Sbjct: 141 GHTGYLSCCRFLDD--NQIVTSSG-DTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTR 197
Query: 469 LCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCFSPN-RYWLCAAFGPSIKIWDLES 296
L SG D A LWD+ +G T H I A+CF PN + + + +++DL +
Sbjct: 198 LFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRA 257
Query: 295 KEMVEELRPEIINQTQTSKTDPPQC--LSLAWSTDGQTLFAGYSDNTIRVW 149
+ + T D C S+++S G+ L AGY D VW
Sbjct: 258 DQ-----------ELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVW 297
Score = 55.6 bits (128), Expect = 2e-07
Identities = 38/141 (26%), Positives = 65/141 (46%), Gaps = 4/141 (2%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK 536
S D T LW+ + + T GH+ V + +P+ + VS D + K+W +
Sbjct: 161 SGDTTCALWD-IETGQQTTTFTGHTGDVMSLSLAPD--TRLFVSGACDASAKLWDVREGM 217
Query: 535 LKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDI---ITALC 365
+ GH +N + P+G+ A+G D L+DL + L T H++I IT++
Sbjct: 218 CRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVS 277
Query: 364 FSPNRYWLCAAFGP-SIKIWD 305
FS + L A + + +WD
Sbjct: 278 FSKSGRLLLAGYDDFNCNVWD 298
Score = 47.2 bits (107), Expect = 6e-05
Identities = 34/121 (28%), Positives = 56/121 (46%), Gaps = 7/121 (5%)
Frame = -2
Query: 643 SDWVSCVRFSPNHANPIIVSCGW-DRTVKVWHLT----NCKLKINHLGHSGYLNTVTVSP 479
S WV ++P+ N V+CG D +++L N ++ GH+GYL+
Sbjct: 97 SSWVMTCAYAPS-GN--YVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLD 153
Query: 478 DGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCFSPN-RYWLCAAFGPSIKIWD 305
D + S G D LWD+ G+ T H + +L +P+ R ++ A S K+WD
Sbjct: 154 DNQIVTSSG-DTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWD 212
Query: 304 L 302
+
Sbjct: 213 V 213
>AL109917-5|CAI95654.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 1 protein.
Length = 340
Score = 72.9 bits (171), Expect = 1e-12
Identities = 50/171 (29%), Positives = 81/171 (47%), Gaps = 4/171 (2%)
Frame = -2
Query: 649 GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGS 470
GH+ ++SC RF + N I+ S G D T +W + + GH+G + +++++PD
Sbjct: 141 GHTGYLSCCRFLDD--NQIVTSSG-DTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTR 197
Query: 469 LCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCFSPN-RYWLCAAFGPSIKIWDLES 296
L SG D A LWD+ +G T H I A+CF PN + + + +++DL +
Sbjct: 198 LFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRA 257
Query: 295 KEMVEELRPEIINQTQTSKTDPPQC--LSLAWSTDGQTLFAGYSDNTIRVW 149
+ + T D C S+++S G+ L AGY D VW
Sbjct: 258 DQ-----------ELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVW 297
Score = 55.6 bits (128), Expect = 2e-07
Identities = 38/141 (26%), Positives = 65/141 (46%), Gaps = 4/141 (2%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK 536
S D T LW+ + + T GH+ V + +P+ + VS D + K+W +
Sbjct: 161 SGDTTCALWD-IETGQQTTTFTGHTGDVMSLSLAPD--TRLFVSGACDASAKLWDVREGM 217
Query: 535 LKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDI---ITALC 365
+ GH +N + P+G+ A+G D L+DL + L T H++I IT++
Sbjct: 218 CRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVS 277
Query: 364 FSPNRYWLCAAFGP-SIKIWD 305
FS + L A + + +WD
Sbjct: 278 FSKSGRLLLAGYDDFNCNVWD 298
Score = 47.2 bits (107), Expect = 6e-05
Identities = 34/121 (28%), Positives = 56/121 (46%), Gaps = 7/121 (5%)
Frame = -2
Query: 643 SDWVSCVRFSPNHANPIIVSCGW-DRTVKVWHLT----NCKLKINHLGHSGYLNTVTVSP 479
S WV ++P+ N V+CG D +++L N ++ GH+GYL+
Sbjct: 97 SSWVMTCAYAPS-GN--YVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLD 153
Query: 478 DGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCFSPN-RYWLCAAFGPSIKIWD 305
D + S G D LWD+ G+ T H + +L +P+ R ++ A S K+WD
Sbjct: 154 DNQIVTSSG-DTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWD 212
Query: 304 L 302
+
Sbjct: 213 V 213
>AL031282-2|CAI20029.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 1 protein.
Length = 340
Score = 72.9 bits (171), Expect = 1e-12
Identities = 50/171 (29%), Positives = 81/171 (47%), Gaps = 4/171 (2%)
Frame = -2
Query: 649 GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGS 470
GH+ ++SC RF + N I+ S G D T +W + + GH+G + +++++PD
Sbjct: 141 GHTGYLSCCRFLDD--NQIVTSSG-DTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTR 197
Query: 469 LCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCFSPN-RYWLCAAFGPSIKIWDLES 296
L SG D A LWD+ +G T H I A+CF PN + + + +++DL +
Sbjct: 198 LFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRA 257
Query: 295 KEMVEELRPEIINQTQTSKTDPPQC--LSLAWSTDGQTLFAGYSDNTIRVW 149
+ + T D C S+++S G+ L AGY D VW
Sbjct: 258 DQ-----------ELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVW 297
Score = 55.6 bits (128), Expect = 2e-07
Identities = 38/141 (26%), Positives = 65/141 (46%), Gaps = 4/141 (2%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK 536
S D T LW+ + + T GH+ V + +P+ + VS D + K+W +
Sbjct: 161 SGDTTCALWD-IETGQQTTTFTGHTGDVMSLSLAPD--TRLFVSGACDASAKLWDVREGM 217
Query: 535 LKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDI---ITALC 365
+ GH +N + P+G+ A+G D L+DL + L T H++I IT++
Sbjct: 218 CRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVS 277
Query: 364 FSPNRYWLCAAFGP-SIKIWD 305
FS + L A + + +WD
Sbjct: 278 FSKSGRLLLAGYDDFNCNVWD 298
Score = 47.2 bits (107), Expect = 6e-05
Identities = 34/121 (28%), Positives = 56/121 (46%), Gaps = 7/121 (5%)
Frame = -2
Query: 643 SDWVSCVRFSPNHANPIIVSCGW-DRTVKVWHLT----NCKLKINHLGHSGYLNTVTVSP 479
S WV ++P+ N V+CG D +++L N ++ GH+GYL+
Sbjct: 97 SSWVMTCAYAPS-GN--YVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLD 153
Query: 478 DGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCFSPN-RYWLCAAFGPSIKIWD 305
D + S G D LWD+ G+ T H + +L +P+ R ++ A S K+WD
Sbjct: 154 DNQIVTSSG-DTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWD 212
Query: 304 L 302
+
Sbjct: 213 V 213
>AF501882-1|AAM15918.1| 340|Homo sapiens guanine nucleotide binding
protein beta 1 protein.
Length = 340
Score = 72.9 bits (171), Expect = 1e-12
Identities = 50/171 (29%), Positives = 81/171 (47%), Gaps = 4/171 (2%)
Frame = -2
Query: 649 GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGS 470
GH+ ++SC RF + N I+ S G D T +W + + GH+G + +++++PD
Sbjct: 141 GHTGYLSCCRFLDD--NQIVTSSG-DTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTR 197
Query: 469 LCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCFSPN-RYWLCAAFGPSIKIWDLES 296
L SG D A LWD+ +G T H I A+CF PN + + + +++DL +
Sbjct: 198 LFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRA 257
Query: 295 KEMVEELRPEIINQTQTSKTDPPQC--LSLAWSTDGQTLFAGYSDNTIRVW 149
+ + T D C S+++S G+ L AGY D VW
Sbjct: 258 DQ-----------ELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVW 297
Score = 55.6 bits (128), Expect = 2e-07
Identities = 38/141 (26%), Positives = 65/141 (46%), Gaps = 4/141 (2%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK 536
S D T LW+ + + T GH+ V + +P+ + VS D + K+W +
Sbjct: 161 SGDTTCALWD-IETGQQTTTFTGHTGDVMSLSLAPD--TRLFVSGACDASAKLWDVREGM 217
Query: 535 LKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDI---ITALC 365
+ GH +N + P+G+ A+G D L+DL + L T H++I IT++
Sbjct: 218 CRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVS 277
Query: 364 FSPNRYWLCAAFGP-SIKIWD 305
FS + L A + + +WD
Sbjct: 278 FSKSGRLLLAGYDDFNCNVWD 298
Score = 47.2 bits (107), Expect = 6e-05
Identities = 34/121 (28%), Positives = 56/121 (46%), Gaps = 7/121 (5%)
Frame = -2
Query: 643 SDWVSCVRFSPNHANPIIVSCGW-DRTVKVWHLT----NCKLKINHLGHSGYLNTVTVSP 479
S WV ++P+ N V+CG D +++L N ++ GH+GYL+
Sbjct: 97 SSWVMTCAYAPS-GN--YVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLD 153
Query: 478 DGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCFSPN-RYWLCAAFGPSIKIWD 305
D + S G D LWD+ G+ T H + +L +P+ R ++ A S K+WD
Sbjct: 154 DNQIVTSSG-DTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWD 212
Query: 304 L 302
+
Sbjct: 213 V 213
>AF070603-1|AAC28655.1| 207|Homo sapiens beta-subunit signal
transducing proteins GS/GI protein.
Length = 207
Score = 72.9 bits (171), Expect = 1e-12
Identities = 50/171 (29%), Positives = 81/171 (47%), Gaps = 4/171 (2%)
Frame = -2
Query: 649 GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGS 470
GH+ ++SC RF + N I+ S G D T +W + + GH+G + +++++PD
Sbjct: 8 GHTGYLSCCRFLDD--NQIVTSSG-DTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTR 64
Query: 469 LCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCFSPN-RYWLCAAFGPSIKIWDLES 296
L SG D A LWD+ +G T H I A+CF PN + + + +++DL +
Sbjct: 65 LFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRA 124
Query: 295 KEMVEELRPEIINQTQTSKTDPPQC--LSLAWSTDGQTLFAGYSDNTIRVW 149
+ + T D C S+++S G+ L AGY D VW
Sbjct: 125 DQ-----------ELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVW 164
Score = 55.6 bits (128), Expect = 2e-07
Identities = 38/141 (26%), Positives = 65/141 (46%), Gaps = 4/141 (2%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK 536
S D T LW+ + + T GH+ V + +P+ + VS D + K+W +
Sbjct: 28 SGDTTCALWD-IETGQQTTTFTGHTGDVMSLSLAPD--TRLFVSGACDASAKLWDVREGM 84
Query: 535 LKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDI---ITALC 365
+ GH +N + P+G+ A+G D L+DL + L T H++I IT++
Sbjct: 85 CRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVS 144
Query: 364 FSPNRYWLCAAFGP-SIKIWD 305
FS + L A + + +WD
Sbjct: 145 FSKSGRLLLAGYDDFNCNVWD 165
>M16538-1|AAA35922.1| 340|Homo sapiens protein ( Human
signal-transducing guanine nucleotide-binding regulatory
(G) protein beta subunit mRNA, complete cds. ).
Length = 340
Score = 72.1 bits (169), Expect = 2e-12
Identities = 50/170 (29%), Positives = 82/170 (48%), Gaps = 3/170 (1%)
Frame = -2
Query: 649 GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGS 470
GH+ ++SC RF + N II S G D T +W + + + GHSG + +++++P+G
Sbjct: 141 GHTGYLSCCRFLDD--NQIITSSG-DTTCALWDIETGQQTVGFAGHSGDVMSLSLAPNGR 197
Query: 469 LCASGGKDMKAMLWDLNDGKHLHT-LDHNDIITALCFSPNRY-WLCAAFGPSIKIWDLES 296
SG D LWD+ D T + H I A+ F PN Y + + + +++DL +
Sbjct: 198 TFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRA 257
Query: 295 -KEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVW 149
+E++ II S+A+S G+ L AGY D +W
Sbjct: 258 DQELLMYSHDNII----------CGITSVAFSRSGRLLLAGYDDFNCNIW 297
Score = 58.0 bits (134), Expect = 3e-08
Identities = 39/141 (27%), Positives = 66/141 (46%), Gaps = 4/141 (2%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK 536
S D T LW+ + + T+ GHS V + +PN + +C D ++K+W + +
Sbjct: 161 SGDTTCALWD-IETGQQTVGFAGHSGDVMSLSLAPNGRTFVSGAC--DASIKLWDVRDSM 217
Query: 535 LKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDI---ITALC 365
+ +GH +N V P+G +G D L+DL + L H++I IT++
Sbjct: 218 CRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMYSHDNIICGITSVA 277
Query: 364 FSPNRYWLCAAFGP-SIKIWD 305
FS + L A + + IWD
Sbjct: 278 FSRSGRLLLAGYDDFNCNIWD 298
>CR456762-1|CAG33043.1| 655|Homo sapiens KATNB1 protein.
Length = 655
Score = 72.1 bits (169), Expect = 2e-12
Identities = 45/142 (31%), Positives = 72/142 (50%), Gaps = 2/142 (1%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAE-CKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
GS+D IKLW+ + C + + GHS V C+RFSP+ + S D TVK+W LT
Sbjct: 123 GSQDTNIKLWDIRRKGCVFRYR--GHSQAVRCLRFSPD--GKWLASAADDHTVKLWDLTA 178
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALC 365
K+ GH+G +N V P+ L ASG D WDL + + ++ + ++
Sbjct: 179 GKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVL 238
Query: 364 FSPNRYWLCAAFGPSIKIWDLE 299
F+P+ L + S++++ E
Sbjct: 239 FNPDGCCLYSGCQDSLRVYGWE 260
Score = 70.9 bits (166), Expect = 4e-12
Identities = 54/194 (27%), Positives = 85/194 (43%), Gaps = 2/194 (1%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
G D + LW+ + + + GH+ V VR N +IV+ +++VW L
Sbjct: 39 GGDDCRVNLWS-INKPNCIMSLTGHTSPVESVRL--NTPEELIVAGSQSGSIRVWDLEAA 95
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDL-NDGKHLHTLDHNDIITALCF 362
K+ +GH + ++ P G ASG +D LWD+ G H+ + L F
Sbjct: 96 KILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRF 155
Query: 361 SPNRYWLC-AAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTL 185
SP+ WL AA ++K+WDL + +M+ E P + P + L L
Sbjct: 156 SPDGKWLASAADDHTVKLWDLTAGKMMSEF-PGHTGPVNVVEFHPNEYL----------L 204
Query: 184 FAGYSDNTIRVWQV 143
+G SD TIR W +
Sbjct: 205 ASGSSDRTIRFWDL 218
Score = 67.3 bits (157), Expect = 5e-11
Identities = 52/192 (27%), Positives = 83/192 (43%), Gaps = 2/192 (1%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
GS+ +I++W+ L K GH + + F P + S D +K+W +
Sbjct: 81 GSQSGSIRVWD-LEAAKILRTLMGHKANICSLDFHPY--GEFVASGSQDTNIKLWDIRRK 137
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCF 362
+ GHS + + SPDG AS D LWDL GK + H + + F
Sbjct: 138 GCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEF 197
Query: 361 SPNRYWLCAAFGP-SIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTL 185
PN Y L + +I+ WDLE ++V + E P S+ ++ DG L
Sbjct: 198 HPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGE-----------PGPVRSVLFNPDGCCL 246
Query: 184 FAGYSDNTIRVW 149
++G D ++RV+
Sbjct: 247 YSGCQD-SLRVY 257
Score = 50.4 bits (115), Expect = 6e-06
Identities = 37/154 (24%), Positives = 69/154 (44%), Gaps = 2/154 (1%)
Frame = -2
Query: 595 IIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLND 416
++ + G D V +W + ++ GH+ + +V ++ L +G + +WDL
Sbjct: 35 LLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEA 94
Query: 415 GKHLHTL-DHNDIITALCFSP-NRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTS 242
K L TL H I +L F P + + +IK+WD+ K V R
Sbjct: 95 AKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYR---------G 145
Query: 241 KTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQVS 140
+ +C L +S DG+ L + D+T+++W ++
Sbjct: 146 HSQAVRC--LRFSPDGKWLASAADDHTVKLWDLT 177
Score = 38.7 bits (86), Expect = 0.021
Identities = 28/129 (21%), Positives = 59/129 (45%), Gaps = 3/129 (2%)
Frame = -2
Query: 520 LGHSGYLNTVTVSP-DGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCF-SPNR 350
+ H+ ++++ + G L A+GG D + LW +N + +L H + ++ +P
Sbjct: 17 VAHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEE 76
Query: 349 YWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYS 170
+ + SI++WDLE+ +++ L N SL + G+ + +G
Sbjct: 77 LIVAGSQSGSIRVWDLEAAKILRTLMGHKAN-----------ICSLDFHPYGEFVASGSQ 125
Query: 169 DNTIRVWQV 143
D I++W +
Sbjct: 126 DTNIKLWDI 134
>BT007022-1|AAP35668.1| 655|Homo sapiens katanin p80
(WD40-containing) subunit B 1 protein.
Length = 655
Score = 72.1 bits (169), Expect = 2e-12
Identities = 45/142 (31%), Positives = 72/142 (50%), Gaps = 2/142 (1%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAE-CKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
GS+D IKLW+ + C + + GHS V C+RFSP+ + S D TVK+W LT
Sbjct: 123 GSQDTNIKLWDIRRKGCVFRYR--GHSQAVRCLRFSPD--GKWLASAADDHTVKLWDLTA 178
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALC 365
K+ GH+G +N V P+ L ASG D WDL + + ++ + ++
Sbjct: 179 GKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVL 238
Query: 364 FSPNRYWLCAAFGPSIKIWDLE 299
F+P+ L + S++++ E
Sbjct: 239 FNPDGCCLYSGCQDSLRVYGWE 260
Score = 70.9 bits (166), Expect = 4e-12
Identities = 54/194 (27%), Positives = 85/194 (43%), Gaps = 2/194 (1%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
G D + LW+ + + + GH+ V VR N +IV+ +++VW L
Sbjct: 39 GGDDCRVNLWS-INKPNCIMSLTGHTSPVESVRL--NTPEELIVAGSQSGSIRVWDLEAA 95
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDL-NDGKHLHTLDHNDIITALCF 362
K+ +GH + ++ P G ASG +D LWD+ G H+ + L F
Sbjct: 96 KILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRF 155
Query: 361 SPNRYWLC-AAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTL 185
SP+ WL AA ++K+WDL + +M+ E P + P + L L
Sbjct: 156 SPDGKWLASAADDHTVKLWDLTAGKMMSEF-PGHTGPVNVVEFHPNEYL----------L 204
Query: 184 FAGYSDNTIRVWQV 143
+G SD TIR W +
Sbjct: 205 ASGSSDRTIRFWDL 218
Score = 67.3 bits (157), Expect = 5e-11
Identities = 52/192 (27%), Positives = 83/192 (43%), Gaps = 2/192 (1%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
GS+ +I++W+ L K GH + + F P + S D +K+W +
Sbjct: 81 GSQSGSIRVWD-LEAAKILRTLMGHKANICSLDFHPY--GEFVASGSQDTNIKLWDIRRK 137
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCF 362
+ GHS + + SPDG AS D LWDL GK + H + + F
Sbjct: 138 GCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEF 197
Query: 361 SPNRYWLCAAFGP-SIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTL 185
PN Y L + +I+ WDLE ++V + E P S+ ++ DG L
Sbjct: 198 HPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGE-----------PGPVRSVLFNPDGCCL 246
Query: 184 FAGYSDNTIRVW 149
++G D ++RV+
Sbjct: 247 YSGCQD-SLRVY 257
Score = 50.4 bits (115), Expect = 6e-06
Identities = 37/154 (24%), Positives = 69/154 (44%), Gaps = 2/154 (1%)
Frame = -2
Query: 595 IIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLND 416
++ + G D V +W + ++ GH+ + +V ++ L +G + +WDL
Sbjct: 35 LLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEA 94
Query: 415 GKHLHTL-DHNDIITALCFSP-NRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTS 242
K L TL H I +L F P + + +IK+WD+ K V R
Sbjct: 95 AKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYR---------G 145
Query: 241 KTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQVS 140
+ +C L +S DG+ L + D+T+++W ++
Sbjct: 146 HSQAVRC--LRFSPDGKWLASAADDHTVKLWDLT 177
Score = 38.7 bits (86), Expect = 0.021
Identities = 28/129 (21%), Positives = 59/129 (45%), Gaps = 3/129 (2%)
Frame = -2
Query: 520 LGHSGYLNTVTVSP-DGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCF-SPNR 350
+ H+ ++++ + G L A+GG D + LW +N + +L H + ++ +P
Sbjct: 17 VAHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEE 76
Query: 349 YWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYS 170
+ + SI++WDLE+ +++ L N SL + G+ + +G
Sbjct: 77 LIVAGSQSGSIRVWDLEAAKILRTLMGHKAN-----------ICSLDFHPYGEFVASGSQ 125
Query: 169 DNTIRVWQV 143
D I++W +
Sbjct: 126 DTNIKLWDI 134
>BC001353-1|AAH01353.1| 655|Homo sapiens katanin p80 (WD repeat
containing) subunit B 1 protein.
Length = 655
Score = 72.1 bits (169), Expect = 2e-12
Identities = 45/142 (31%), Positives = 72/142 (50%), Gaps = 2/142 (1%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAE-CKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
GS+D IKLW+ + C + + GHS V C+RFSP+ + S D TVK+W LT
Sbjct: 123 GSQDTNIKLWDIRRKGCVFRYR--GHSQAVRCLRFSPD--GKWLASAADDHTVKLWDLTA 178
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALC 365
K+ GH+G +N V P+ L ASG D WDL + + ++ + ++
Sbjct: 179 GKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVL 238
Query: 364 FSPNRYWLCAAFGPSIKIWDLE 299
F+P+ L + S++++ E
Sbjct: 239 FNPDGCCLYSGCQDSLRVYGWE 260
Score = 70.9 bits (166), Expect = 4e-12
Identities = 54/194 (27%), Positives = 85/194 (43%), Gaps = 2/194 (1%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
G D + LW+ + + + GH+ V VR N +IV+ +++VW L
Sbjct: 39 GGDDCRVNLWS-INKPNCIMSLTGHTSPVESVRL--NTPEELIVAGSQSGSIRVWDLEAA 95
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDL-NDGKHLHTLDHNDIITALCF 362
K+ +GH + ++ P G ASG +D LWD+ G H+ + L F
Sbjct: 96 KILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRF 155
Query: 361 SPNRYWLC-AAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTL 185
SP+ WL AA ++K+WDL + +M+ E P + P + L L
Sbjct: 156 SPDGKWLASAADDHTVKLWDLTAGKMMSEF-PGHTGPVNVVEFHPNEYL----------L 204
Query: 184 FAGYSDNTIRVWQV 143
+G SD TIR W +
Sbjct: 205 ASGSSDRTIRFWDL 218
Score = 67.3 bits (157), Expect = 5e-11
Identities = 52/192 (27%), Positives = 83/192 (43%), Gaps = 2/192 (1%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
GS+ +I++W+ L K GH + + F P + S D +K+W +
Sbjct: 81 GSQSGSIRVWD-LEAAKILRTLMGHKANICSLDFHPY--GEFVASGSQDTNIKLWDIRRK 137
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCF 362
+ GHS + + SPDG AS D LWDL GK + H + + F
Sbjct: 138 GCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEF 197
Query: 361 SPNRYWLCAAFGP-SIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTL 185
PN Y L + +I+ WDLE ++V + E P S+ ++ DG L
Sbjct: 198 HPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGE-----------PGPVRSVLFNPDGCCL 246
Query: 184 FAGYSDNTIRVW 149
++G D ++RV+
Sbjct: 247 YSGCQD-SLRVY 257
Score = 50.4 bits (115), Expect = 6e-06
Identities = 37/154 (24%), Positives = 69/154 (44%), Gaps = 2/154 (1%)
Frame = -2
Query: 595 IIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLND 416
++ + G D V +W + ++ GH+ + +V ++ L +G + +WDL
Sbjct: 35 LLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEA 94
Query: 415 GKHLHTL-DHNDIITALCFSP-NRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTS 242
K L TL H I +L F P + + +IK+WD+ K V R
Sbjct: 95 AKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYR---------G 145
Query: 241 KTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQVS 140
+ +C L +S DG+ L + D+T+++W ++
Sbjct: 146 HSQAVRC--LRFSPDGKWLASAADDHTVKLWDLT 177
Score = 38.7 bits (86), Expect = 0.021
Identities = 28/129 (21%), Positives = 59/129 (45%), Gaps = 3/129 (2%)
Frame = -2
Query: 520 LGHSGYLNTVTVSP-DGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCF-SPNR 350
+ H+ ++++ + G L A+GG D + LW +N + +L H + ++ +P
Sbjct: 17 VAHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEE 76
Query: 349 YWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYS 170
+ + SI++WDLE+ +++ L N SL + G+ + +G
Sbjct: 77 LIVAGSQSGSIRVWDLEAAKILRTLMGHKAN-----------ICSLDFHPYGEFVASGSQ 125
Query: 169 DNTIRVWQV 143
D I++W +
Sbjct: 126 DTNIKLWDI 134
>AF001687-1|AAB87640.1| 521|Homo sapiens U4/U6 snRNP 60 kDa protein
protein.
Length = 521
Score = 72.1 bits (169), Expect = 2e-12
Identities = 55/189 (29%), Positives = 88/189 (46%), Gaps = 2/189 (1%)
Frame = -2
Query: 709 DKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLK 530
D ++KLW+ L + +GH+ V+ V + P+ + +C +DR+ ++W L +
Sbjct: 301 DGSVKLWS-LDSDEPVADIEGHTVRVARVMWHPS-GRFLGTTC-YDRSWRLWDLEAQEEI 357
Query: 529 INHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCFSPN 353
++ GHS + + DGSL +GG D +WDL G+ + L DH I + FSPN
Sbjct: 358 LHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEDHLKEIYGINFSPN 417
Query: 352 RYWLCAAFGP-SIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAG 176
Y + G + K+WDL + V + P N K +P G L G
Sbjct: 418 GYHIATGSGDNTCKVWDLRQRRCVYTIPPH-QNLVTGVKFEP---------IHGNFLLTG 467
Query: 175 YSDNTIRVW 149
DNT ++W
Sbjct: 468 AYDNTAKIW 476
Score = 53.6 bits (123), Expect = 7e-07
Identities = 33/100 (33%), Positives = 47/100 (47%), Gaps = 1/100 (1%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAE-CKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
GS D T K+W+ C YTI H + V+ V+F P H N +++ +D T K+W
Sbjct: 424 GSGDNTCKVWDLRQRRCVYTIPP--HQNLVTGVKFEPIHGN-FLLTGAYDNTAKIWTHPG 480
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDL 422
GH G + + +S DG L A+ D LW L
Sbjct: 481 WSPLKTLAGHEGKVMGLDISSDGQLIATYSYDRTFKLWML 520
Score = 43.6 bits (98), Expect = 7e-04
Identities = 42/174 (24%), Positives = 75/174 (43%), Gaps = 10/174 (5%)
Frame = -2
Query: 634 VSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYL--------NTVTVSP 479
+S FSPN + ++ + W K+W + +C L GH+ + +TV++ P
Sbjct: 233 ISYCHFSPN--SKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTVSLDP 290
Query: 478 DGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALCFSPN-RYWLCAAFGPSIKIWD 305
AS D LW L+ + + ++ H + + + P+ R+ + S ++WD
Sbjct: 291 KDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWD 350
Query: 304 LESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQV 143
LE++E EI++Q S +A+ DG G D RVW +
Sbjct: 351 LEAQE-------EILHQEGHSM----GVYDIAFHQDGSLAGTGGLDAFGRVWDL 393
Score = 41.9 bits (94), Expect = 0.002
Identities = 44/194 (22%), Positives = 76/194 (39%), Gaps = 9/194 (4%)
Frame = -2
Query: 697 KLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPI------IVSCGWDRTVKVWHLTNCK 536
KLW+ + +C GH+ V + F P + + SC D +VK+W L + +
Sbjct: 255 KLWS-VPDCNLLHTLRGHNTNVGAIVFHPKSTVSLDPKDVNLASCAADGSVKLWSLDSDE 313
Query: 535 LKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKH-LHTLDHNDIITALCFS 359
+ GH+ + V P G + D LWDL + LH H+ + + F
Sbjct: 314 PVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFH 373
Query: 358 PNRYWLCAAFGPSI--KIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTL 185
+ L G ++WDL + + L + + + +S +G +
Sbjct: 374 QDGS-LAGTGGLDAFGRVWDLRTGRCIMFLEDHL-----------KEIYGINFSPNGYHI 421
Query: 184 FAGYSDNTIRVWQV 143
G DNT +VW +
Sbjct: 422 ATGSGDNTCKVWDL 435
>AF052432-1|AAC09328.1| 655|Homo sapiens katanin p80 subunit
protein.
Length = 655
Score = 71.3 bits (167), Expect = 3e-12
Identities = 45/142 (31%), Positives = 72/142 (50%), Gaps = 2/142 (1%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAE-CKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
GS+D IKLW+ + C + + GHS V C+RFSP+ + S D TVK+W LT
Sbjct: 123 GSQDTNIKLWDIRRKGCVFRYR--GHSQAVRCLRFSPD--GKWLASAADDHTVKLWDLTA 178
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALC 365
K+ GH+G +N V P+ L ASG D WDL + + ++ + ++
Sbjct: 179 GKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDGTIRFWDLEKFQVVSRIEGEPGPVRSVL 238
Query: 364 FSPNRYWLCAAFGPSIKIWDLE 299
F+P+ L + S++++ E
Sbjct: 239 FNPDGCCLYSGCQDSLRVYGWE 260
Score = 67.3 bits (157), Expect = 5e-11
Identities = 49/181 (27%), Positives = 80/181 (44%), Gaps = 2/181 (1%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
G D + LW+ + + + GH+ V VR N +IV+ +++VW L
Sbjct: 39 GGDDCRVNLWS-INKPNCIMSLTGHTSPVESVRL--NTPEELIVAGSQSGSIRVWDLEAA 95
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDL-NDGKHLHTLDHNDIITALCF 362
K+ +G + ++ P G ASG +D LWD+ G H+ + L F
Sbjct: 96 KILRTLMGLKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRF 155
Query: 361 SPNRYWLC-AAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTL 185
SP+ WL AA ++K+WDL + +M+ E P + P + L + S+DG
Sbjct: 156 SPDGKWLASAADDHTVKLWDLTAGKMMSEF-PGHTGPVNVVEFHPNEYLLASGSSDGTIR 214
Query: 184 F 182
F
Sbjct: 215 F 215
Score = 64.5 bits (150), Expect = 4e-10
Identities = 51/192 (26%), Positives = 82/192 (42%), Gaps = 2/192 (1%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
GS+ +I++W+ L K G + + F P + S D +K+W +
Sbjct: 81 GSQSGSIRVWD-LEAAKILRTLMGLKANICSLDFHPY--GEFVASGSQDTNIKLWDIRRK 137
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCF 362
+ GHS + + SPDG AS D LWDL GK + H + + F
Sbjct: 138 GCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEF 197
Query: 361 SPNRYWLCAAFGP-SIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTL 185
PN Y L + +I+ WDLE ++V + E P S+ ++ DG L
Sbjct: 198 HPNEYLLASGSSDGTIRFWDLEKFQVVSRIEGE-----------PGPVRSVLFNPDGCCL 246
Query: 184 FAGYSDNTIRVW 149
++G D ++RV+
Sbjct: 247 YSGCQD-SLRVY 257
Score = 46.0 bits (104), Expect = 1e-04
Identities = 36/154 (23%), Positives = 68/154 (44%), Gaps = 2/154 (1%)
Frame = -2
Query: 595 IIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLND 416
++ + G D V +W + ++ GH+ + +V ++ L +G + +WDL
Sbjct: 35 LLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEA 94
Query: 415 GKHLHTL-DHNDIITALCFSP-NRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTS 242
K L TL I +L F P + + +IK+WD+ K V R
Sbjct: 95 AKILRTLMGLKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYR---------G 145
Query: 241 KTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQVS 140
+ +C L +S DG+ L + D+T+++W ++
Sbjct: 146 HSQAVRC--LRFSPDGKWLASAADDHTVKLWDLT 177
Score = 37.5 bits (83), Expect = 0.048
Identities = 28/129 (21%), Positives = 59/129 (45%), Gaps = 3/129 (2%)
Frame = -2
Query: 520 LGHSGYLNTVTVSP-DGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCF-SPNR 350
+ H+ ++++ + G L A+GG D + LW +N + +L H + ++ +P
Sbjct: 17 VAHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEE 76
Query: 349 YWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYS 170
+ + SI++WDLE+ +++ L N SL + G+ + +G
Sbjct: 77 LIVAGSQSGSIRVWDLEAAKILRTLMGLKAN-----------ICSLDFHPYGEFVASGSQ 125
Query: 169 DNTIRVWQV 143
D I++W +
Sbjct: 126 DTNIKLWDI 134
>BC036377-1|AAH36377.1| 415|Homo sapiens WD repeat domain 69
protein.
Length = 415
Score = 70.5 bits (165), Expect = 6e-12
Identities = 41/150 (27%), Positives = 78/150 (52%), Gaps = 2/150 (1%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
GS D+T KLW+T + + + GH + V + F+ + + I +D+T K+W +
Sbjct: 110 GSYDRTCKLWDTASGEELNTLE-GHRNVVYAIAFNNPYGDKIATG-SFDKTCKLWSVETG 167
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCF 362
K GH+ + ++ +P +L A+G D A LWD+ +G+ ++TL H+ I +L F
Sbjct: 168 KCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQNGEEVYTLRGHSAEIISLSF 227
Query: 361 SPN-RYWLCAAFGPSIKIWDLESKEMVEEL 275
+ + + +F ++ +WD ++ V L
Sbjct: 228 NTSGDRIITGSFDHTVVVWDADTGRKVNIL 257
Score = 66.1 bits (154), Expect = 1e-10
Identities = 56/194 (28%), Positives = 94/194 (48%), Gaps = 4/194 (2%)
Frame = -2
Query: 718 GSRDKTIKLWNTL-AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
GS D T KLW+ E YT++ GHS + + F N + I++ +D TV VW
Sbjct: 195 GSMDTTAKLWDIQNGEEVYTLR--GHSAEIISLSF--NTSGDRIITGSFDHTVVVWDADT 250
Query: 541 CKLKINHL-GHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITAL 368
+ K+N L GH +++ + + D SL +G D LWD +GK + TL H+D I
Sbjct: 251 GR-KVNILIGHCAEISSASFNWDCSLILTGSMDKTCKLWDATNGKCVATLTGHDDEILDS 309
Query: 367 CFS-PNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQ 191
CF + A+ + +I+ +++ + +L ++ + SK ++++ G
Sbjct: 310 CFDYTGKLIATASADGTARIFSAATRKCIAKLEG---HEGEISK--------ISFNPQGN 358
Query: 190 TLFAGYSDNTIRVW 149
L G SD T R+W
Sbjct: 359 HLLTGSSDKTARIW 372
Score = 58.4 bits (135), Expect = 2e-08
Identities = 36/122 (29%), Positives = 59/122 (48%), Gaps = 2/122 (1%)
Frame = -2
Query: 718 GSRDKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
GS DKT KLW+ T +C T+ GH D + F ++ +I + D T +++
Sbjct: 279 GSMDKTCKLWDATNGKCVATLT--GHDDEILDSCF--DYTGKLIATASADGTARIFSAAT 334
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALC 365
K GH G ++ ++ +P G+ +G D A +WD G+ L L+ H D I +
Sbjct: 335 RKCIAKLEGHEGEISKISFNPQGNHLLTGSSDKTARIWDAQTGQCLQVLEGHTDEIFSCA 394
Query: 364 FS 359
F+
Sbjct: 395 FN 396
Score = 56.4 bits (130), Expect = 1e-07
Identities = 49/193 (25%), Positives = 82/193 (42%), Gaps = 2/193 (1%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
GS D T+ +W+ K I GH +S F N +I++ D+T K+W TN
Sbjct: 237 GSFDHTVVVWDADTGRKVNILI-GHCAEISSASF--NWDCSLILTGSMDKTCKLWDATNG 293
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALCF 362
K GH + G L A+ D A ++ K + L+ H I+ + F
Sbjct: 294 KCVATLTGHDDEILDSCFDYTGKLIATASADGTARIFSAATRKCIAKLEGHEGEISKISF 353
Query: 361 SPN-RYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTL 185
+P + L + + +IWD ++ + ++ L TD + S A++ G +
Sbjct: 354 NPQGNHLLTGSSDKTARIWDAQTGQCLQVLE---------GHTD--EIFSCAFNYKGNIV 402
Query: 184 FAGYSDNTIRVWQ 146
G DNT R+W+
Sbjct: 403 ITGSKDNTCRIWR 415
>AK097409-1|BAC05039.1| 415|Homo sapiens protein ( Homo sapiens
cDNA FLJ40090 fis, clone TESTI2003596, weakly similar to
VEGETATIBLE INCOMPATIBILITY PROTEIN HET-E-1. ).
Length = 415
Score = 70.5 bits (165), Expect = 6e-12
Identities = 41/150 (27%), Positives = 78/150 (52%), Gaps = 2/150 (1%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
GS D+T KLW+T + + + GH + V + F+ + + I +D+T K+W +
Sbjct: 110 GSYDRTCKLWDTASGEELNTLE-GHRNVVYAIAFNNPYGDKIATG-SFDKTCKLWSVETG 167
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCF 362
K GH+ + ++ +P +L A+G D A LWD+ +G+ ++TL H+ I +L F
Sbjct: 168 KCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQNGEEVYTLRGHSAEIISLSF 227
Query: 361 SPN-RYWLCAAFGPSIKIWDLESKEMVEEL 275
+ + + +F ++ +WD ++ V L
Sbjct: 228 NTSGDRIITGSFDHTVVVWDADTGRKVNIL 257
Score = 66.1 bits (154), Expect = 1e-10
Identities = 56/194 (28%), Positives = 94/194 (48%), Gaps = 4/194 (2%)
Frame = -2
Query: 718 GSRDKTIKLWNTL-AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
GS D T KLW+ E YT++ GHS + + F N + I++ +D TV VW
Sbjct: 195 GSMDTTAKLWDIQNGEEVYTLR--GHSAEIISLSF--NTSGDRIITGSFDHTVVVWDADT 250
Query: 541 CKLKINHL-GHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITAL 368
+ K+N L GH +++ + + D SL +G D LWD +GK + TL H+D I
Sbjct: 251 GR-KVNILIGHCAEISSASFNWDCSLILTGSMDKTCKLWDATNGKCVATLTGHDDEILDS 309
Query: 367 CFS-PNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQ 191
CF + A+ + +I+ +++ + +L ++ + SK ++++ G
Sbjct: 310 CFDYTGKLIATASADGTARIFSAATRKCIAKLEG---HEGEISK--------ISFNPQGN 358
Query: 190 TLFAGYSDNTIRVW 149
L G SD T R+W
Sbjct: 359 HLLTGSSDKTARIW 372
Score = 58.4 bits (135), Expect = 2e-08
Identities = 36/122 (29%), Positives = 59/122 (48%), Gaps = 2/122 (1%)
Frame = -2
Query: 718 GSRDKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
GS DKT KLW+ T +C T+ GH D + F ++ +I + D T +++
Sbjct: 279 GSMDKTCKLWDATNGKCVATLT--GHDDEILDSCF--DYTGKLIATASADGTARIFSAAT 334
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALC 365
K GH G ++ ++ +P G+ +G D A +WD G+ L L+ H D I +
Sbjct: 335 RKCIAKLEGHEGEISKISFNPQGNHLLTGSSDKTARIWDAQTGQCLQVLEGHTDEIFSCA 394
Query: 364 FS 359
F+
Sbjct: 395 FN 396
Score = 56.4 bits (130), Expect = 1e-07
Identities = 49/193 (25%), Positives = 82/193 (42%), Gaps = 2/193 (1%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
GS D T+ +W+ K I GH +S F N +I++ D+T K+W TN
Sbjct: 237 GSFDHTVVVWDADTGRKVNILI-GHCAEISSASF--NWDCSLILTGSMDKTCKLWDATNG 293
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALCF 362
K GH + G L A+ D A ++ K + L+ H I+ + F
Sbjct: 294 KCVATLTGHDDEILDSCFDYTGKLIATASADGTARIFSAATRKCIAKLEGHEGEISKISF 353
Query: 361 SPN-RYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTL 185
+P + L + + +IWD ++ + ++ L TD + S A++ G +
Sbjct: 354 NPQGNHLLTGSSDKTARIWDAQTGQCLQVLE---------GHTD--EIFSCAFNYKGNIV 402
Query: 184 FAGYSDNTIRVWQ 146
G DNT R+W+
Sbjct: 403 ITGSKDNTCRIWR 415
>AC073065-2|AAX93215.1| 415|Homo sapiens unknown protein.
Length = 415
Score = 70.5 bits (165), Expect = 6e-12
Identities = 41/150 (27%), Positives = 78/150 (52%), Gaps = 2/150 (1%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
GS D+T KLW+T + + + GH + V + F+ + + I +D+T K+W +
Sbjct: 110 GSYDRTCKLWDTASGEELNTLE-GHRNVVYAIAFNNPYGDKIATG-SFDKTCKLWSVETG 167
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCF 362
K GH+ + ++ +P +L A+G D A LWD+ +G+ ++TL H+ I +L F
Sbjct: 168 KCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQNGEEVYTLRGHSAEIISLSF 227
Query: 361 SPN-RYWLCAAFGPSIKIWDLESKEMVEEL 275
+ + + +F ++ +WD ++ V L
Sbjct: 228 NTSGDRIITGSFDHTVVVWDADTGRKVNIL 257
Score = 66.1 bits (154), Expect = 1e-10
Identities = 56/194 (28%), Positives = 94/194 (48%), Gaps = 4/194 (2%)
Frame = -2
Query: 718 GSRDKTIKLWNTL-AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
GS D T KLW+ E YT++ GHS + + F N + I++ +D TV VW
Sbjct: 195 GSMDTTAKLWDIQNGEEVYTLR--GHSAEIISLSF--NTSGDRIITGSFDHTVVVWDADT 250
Query: 541 CKLKINHL-GHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITAL 368
+ K+N L GH +++ + + D SL +G D LWD +GK + TL H+D I
Sbjct: 251 GR-KVNILIGHCAEISSASFNWDCSLILTGSMDKTCKLWDATNGKCVATLTGHDDEILDS 309
Query: 367 CFS-PNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQ 191
CF + A+ + +I+ +++ + +L ++ + SK ++++ G
Sbjct: 310 CFDYTGKLIATASADGTARIFSAATRKCIAKLEG---HEGEISK--------ISFNPQGN 358
Query: 190 TLFAGYSDNTIRVW 149
L G SD T R+W
Sbjct: 359 HLLTGSSDKTARIW 372
Score = 58.4 bits (135), Expect = 2e-08
Identities = 36/122 (29%), Positives = 59/122 (48%), Gaps = 2/122 (1%)
Frame = -2
Query: 718 GSRDKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
GS DKT KLW+ T +C T+ GH D + F ++ +I + D T +++
Sbjct: 279 GSMDKTCKLWDATNGKCVATLT--GHDDEILDSCF--DYTGKLIATASADGTARIFSAAT 334
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALC 365
K GH G ++ ++ +P G+ +G D A +WD G+ L L+ H D I +
Sbjct: 335 RKCIAKLEGHEGEISKISFNPQGNHLLTGSSDKTARIWDAQTGQCLQVLEGHTDEIFSCA 394
Query: 364 FS 359
F+
Sbjct: 395 FN 396
Score = 56.4 bits (130), Expect = 1e-07
Identities = 49/193 (25%), Positives = 82/193 (42%), Gaps = 2/193 (1%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
GS D T+ +W+ K I GH +S F N +I++ D+T K+W TN
Sbjct: 237 GSFDHTVVVWDADTGRKVNILI-GHCAEISSASF--NWDCSLILTGSMDKTCKLWDATNG 293
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALCF 362
K GH + G L A+ D A ++ K + L+ H I+ + F
Sbjct: 294 KCVATLTGHDDEILDSCFDYTGKLIATASADGTARIFSAATRKCIAKLEGHEGEISKISF 353
Query: 361 SPN-RYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTL 185
+P + L + + +IWD ++ + ++ L TD + S A++ G +
Sbjct: 354 NPQGNHLLTGSSDKTARIWDAQTGQCLQVLE---------GHTD--EIFSCAFNYKGNIV 402
Query: 184 FAGYSDNTIRVWQ 146
G DNT R+W+
Sbjct: 403 ITGSKDNTCRIWR 415
>U82756-1|AAC02261.1| 520|Homo sapiens WD splicing factor Hprp4p
protein.
Length = 520
Score = 69.7 bits (163), Expect = 1e-11
Identities = 54/189 (28%), Positives = 88/189 (46%), Gaps = 2/189 (1%)
Frame = -2
Query: 709 DKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLK 530
D ++KLW+ L + +GH+ V+ V + P+ + +C +DR+ ++W L +
Sbjct: 300 DGSVKLWS-LDSDEPVADIEGHTVRVARVMWHPS-GRFLGTTC-YDRSWRLWDLEAQEEI 356
Query: 529 INHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALCFSPN 353
++ GHS + + DGSL +GG D +WDL G+ + L+ H I + FSPN
Sbjct: 357 LHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPN 416
Query: 352 RYWLCAAFGP-SIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAG 176
Y + G + K+WDL + V + P N K +P G L G
Sbjct: 417 GYHIATGSGDNTCKVWDLRQRRCVYTI-PAHQNLVTGVKFEP---------IHGNFLLTG 466
Query: 175 YSDNTIRVW 149
DNT ++W
Sbjct: 467 AYDNTAKIW 475
Score = 53.6 bits (123), Expect = 7e-07
Identities = 32/98 (32%), Positives = 46/98 (46%), Gaps = 1/98 (1%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAE-CKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
GS D T K+W+ C YTI H + V+ V+F P H N +++ +D T K+W
Sbjct: 423 GSGDNTCKVWDLRQRRCVYTIP--AHQNLVTGVKFEPIHGN-FLLTGAYDNTAKIWTHPG 479
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLW 428
GH G + + +S DG L A+ D LW
Sbjct: 480 WSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLW 517
Score = 42.3 bits (95), Expect = 0.002
Identities = 43/174 (24%), Positives = 74/174 (42%), Gaps = 10/174 (5%)
Frame = -2
Query: 634 VSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLG--------HSGYLNTVTVSP 479
+S FSPN + ++ + W K+W + +C L G HS +TV++ P
Sbjct: 232 ISYCHFSPN--SKMLATACWSGLCKLWSVPDCNLLHTLRGHNTKKEQLHSIPKSTVSLDP 289
Query: 478 DGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALCFSPN-RYWLCAAFGPSIKIWD 305
AS D LW L+ + + ++ H + + + P+ R+ + S ++WD
Sbjct: 290 KDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWD 349
Query: 304 LESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQV 143
LE++E EI++Q S +A+ DG G D RVW +
Sbjct: 350 LEAQE-------EILHQEGHSM----GVYDIAFHQDGSLAGTGGLDAFGRVWDL 392
Score = 40.7 bits (91), Expect = 0.005
Identities = 42/177 (23%), Positives = 70/177 (39%), Gaps = 3/177 (1%)
Frame = -2
Query: 664 TIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTV 485
T ++ HS S V P N + SC D +VK+W L + + + GH+ + V
Sbjct: 272 TKKEQLHSIPKSTVSLDPKDVN--LASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMW 329
Query: 484 SPDGSLCASGGKDMKAMLWDLNDGKH-LHTLDHNDIITALCFSPNRYWLCAAFGPSI--K 314
P G + D LWDL + LH H+ + + F + L G +
Sbjct: 330 HPSGRFLGTTCYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGS-LAGTGGLDAFGR 388
Query: 313 IWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQV 143
+WDL + + L + + + +S +G + G DNT +VW +
Sbjct: 389 VWDLRTGRCIMFLEGHL-----------KEIYGINFSPNGYHIATGSGDNTCKVWDL 434
>CR457105-1|CAG33386.1| 521|Homo sapiens PRPF4 protein.
Length = 521
Score = 69.7 bits (163), Expect = 1e-11
Identities = 54/189 (28%), Positives = 88/189 (46%), Gaps = 2/189 (1%)
Frame = -2
Query: 709 DKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLK 530
D ++KLW+ L + +GH+ V+ V + P+ + +C +DR+ ++W L +
Sbjct: 301 DGSVKLWS-LDSDEPVADIEGHTVRVARVMWHPS-GRFLGTTC-YDRSWRLWDLEAQEEI 357
Query: 529 INHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALCFSPN 353
++ GHS + + DGSL +GG D +WDL G+ + L+ H I + FSPN
Sbjct: 358 LHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPN 417
Query: 352 RYWLCAAFGP-SIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAG 176
Y + G + K+WDL + V + P N K +P G L G
Sbjct: 418 GYHIATGSGDNTCKVWDLRQRRCVYTI-PAHQNLVTGVKFEP---------IHGNFLLTG 467
Query: 175 YSDNTIRVW 149
DNT ++W
Sbjct: 468 AYDNTAKIW 476
Score = 53.6 bits (123), Expect = 7e-07
Identities = 32/98 (32%), Positives = 46/98 (46%), Gaps = 1/98 (1%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAE-CKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
GS D T K+W+ C YTI H + V+ V+F P H N +++ +D T K+W
Sbjct: 424 GSGDNTCKVWDLRQRRCVYTIP--AHQNLVTGVKFEPIHGN-FLLTGAYDNTAKIWTHPG 480
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLW 428
GH G + + +S DG L A+ D LW
Sbjct: 481 WSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLW 518
Score = 43.6 bits (98), Expect = 7e-04
Identities = 42/174 (24%), Positives = 75/174 (43%), Gaps = 10/174 (5%)
Frame = -2
Query: 634 VSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYL--------NTVTVSP 479
+S FSPN + ++ + W K+W + +C L GH+ + +TV++ P
Sbjct: 233 ISYCHFSPN--SKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTVSLDP 290
Query: 478 DGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALCFSPN-RYWLCAAFGPSIKIWD 305
AS D LW L+ + + ++ H + + + P+ R+ + S ++WD
Sbjct: 291 KDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWD 350
Query: 304 LESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQV 143
LE++E EI++Q S +A+ DG G D RVW +
Sbjct: 351 LEAQE-------EILHQEGHSM----GVYDIAFHQDGSLAGTGGLDAFGRVWDL 393
Score = 41.5 bits (93), Expect = 0.003
Identities = 44/194 (22%), Positives = 76/194 (39%), Gaps = 9/194 (4%)
Frame = -2
Query: 697 KLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPI------IVSCGWDRTVKVWHLTNCK 536
KLW+ + +C GH+ V + F P + + SC D +VK+W L + +
Sbjct: 255 KLWS-VPDCNLLHTLRGHNTNVGAIVFHPKSTVSLDPKDVNLASCAADGSVKLWSLDSDE 313
Query: 535 LKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKH-LHTLDHNDIITALCFS 359
+ GH+ + V P G + D LWDL + LH H+ + + F
Sbjct: 314 PVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFH 373
Query: 358 PNRYWLCAAFGPSI--KIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTL 185
+ L G ++WDL + + L + + + +S +G +
Sbjct: 374 QDGS-LAGTGGLDAFGRVWDLRTGRCIMFLEGHL-----------KEIYGINFSPNGYHI 421
Query: 184 FAGYSDNTIRVWQV 143
G DNT +VW +
Sbjct: 422 ATGSGDNTCKVWDL 435
>BC007424-1|AAH07424.1| 521|Homo sapiens PRP4 pre-mRNA processing
factor 4 homolog (yeast) protein.
Length = 521
Score = 69.7 bits (163), Expect = 1e-11
Identities = 54/189 (28%), Positives = 88/189 (46%), Gaps = 2/189 (1%)
Frame = -2
Query: 709 DKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLK 530
D ++KLW+ L + +GH+ V+ V + P+ + +C +DR+ ++W L +
Sbjct: 301 DGSVKLWS-LDSDEPVADIEGHTVRVARVMWHPS-GRFLGTTC-YDRSWRLWDLEAQEEI 357
Query: 529 INHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALCFSPN 353
++ GHS + + DGSL +GG D +WDL G+ + L+ H I + FSPN
Sbjct: 358 LHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPN 417
Query: 352 RYWLCAAFGP-SIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAG 176
Y + G + K+WDL + V + P N K +P G L G
Sbjct: 418 GYHIATGSGDNTCKVWDLRQRRCVYTI-PAHQNLVTGVKFEP---------IHGNFLLTG 467
Query: 175 YSDNTIRVW 149
DNT ++W
Sbjct: 468 AYDNTAKIW 476
Score = 53.6 bits (123), Expect = 7e-07
Identities = 32/98 (32%), Positives = 46/98 (46%), Gaps = 1/98 (1%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAE-CKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
GS D T K+W+ C YTI H + V+ V+F P H N +++ +D T K+W
Sbjct: 424 GSGDNTCKVWDLRQRRCVYTIP--AHQNLVTGVKFEPIHGN-FLLTGAYDNTAKIWTHPG 480
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLW 428
GH G + + +S DG L A+ D LW
Sbjct: 481 WSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLW 518
Score = 43.6 bits (98), Expect = 7e-04
Identities = 42/174 (24%), Positives = 75/174 (43%), Gaps = 10/174 (5%)
Frame = -2
Query: 634 VSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYL--------NTVTVSP 479
+S FSPN + ++ + W K+W + +C L GH+ + +TV++ P
Sbjct: 233 ISYCHFSPN--SKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTVSLDP 290
Query: 478 DGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALCFSPN-RYWLCAAFGPSIKIWD 305
AS D LW L+ + + ++ H + + + P+ R+ + S ++WD
Sbjct: 291 KDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWD 350
Query: 304 LESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQV 143
LE++E EI++Q S +A+ DG G D RVW +
Sbjct: 351 LEAQE-------EILHQEGHSM----GVYDIAFHQDGSLAGTGGLDAFGRVWDL 393
Score = 41.5 bits (93), Expect = 0.003
Identities = 44/194 (22%), Positives = 76/194 (39%), Gaps = 9/194 (4%)
Frame = -2
Query: 697 KLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPI------IVSCGWDRTVKVWHLTNCK 536
KLW+ + +C GH+ V + F P + + SC D +VK+W L + +
Sbjct: 255 KLWS-VPDCNLLHTLRGHNTNVGAIVFHPKSTVSLDPKDVNLASCAADGSVKLWSLDSDE 313
Query: 535 LKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKH-LHTLDHNDIITALCFS 359
+ GH+ + V P G + D LWDL + LH H+ + + F
Sbjct: 314 PVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFH 373
Query: 358 PNRYWLCAAFGPSI--KIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTL 185
+ L G ++WDL + + L + + + +S +G +
Sbjct: 374 QDGS-LAGTGGLDAFGRVWDLRTGRCIMFLEGHL-----------KEIYGINFSPNGYHI 421
Query: 184 FAGYSDNTIRVWQV 143
G DNT +VW +
Sbjct: 422 ATGSGDNTCKVWDL 435
>BC001588-1|AAH01588.1| 522|Homo sapiens PRP4 pre-mRNA processing
factor 4 homolog (yeast) protein.
Length = 522
Score = 69.7 bits (163), Expect = 1e-11
Identities = 54/189 (28%), Positives = 88/189 (46%), Gaps = 2/189 (1%)
Frame = -2
Query: 709 DKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLK 530
D ++KLW+ L + +GH+ V+ V + P+ + +C +DR+ ++W L +
Sbjct: 302 DGSVKLWS-LDSDEPVADIEGHTVRVARVMWHPS-GRFLGTTC-YDRSWRLWDLEAQEEI 358
Query: 529 INHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALCFSPN 353
++ GHS + + DGSL +GG D +WDL G+ + L+ H I + FSPN
Sbjct: 359 LHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPN 418
Query: 352 RYWLCAAFGP-SIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAG 176
Y + G + K+WDL + V + P N K +P G L G
Sbjct: 419 GYHIATGSGDNTCKVWDLRQRRCVYTI-PAHQNLVTGVKFEP---------IHGNFLLTG 468
Query: 175 YSDNTIRVW 149
DNT ++W
Sbjct: 469 AYDNTAKIW 477
Score = 53.6 bits (123), Expect = 7e-07
Identities = 32/98 (32%), Positives = 46/98 (46%), Gaps = 1/98 (1%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAE-CKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
GS D T K+W+ C YTI H + V+ V+F P H N +++ +D T K+W
Sbjct: 425 GSGDNTCKVWDLRQRRCVYTIP--AHQNLVTGVKFEPIHGN-FLLTGAYDNTAKIWTHPG 481
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLW 428
GH G + + +S DG L A+ D LW
Sbjct: 482 WSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLW 519
Score = 43.6 bits (98), Expect = 7e-04
Identities = 42/174 (24%), Positives = 75/174 (43%), Gaps = 10/174 (5%)
Frame = -2
Query: 634 VSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYL--------NTVTVSP 479
+S FSPN + ++ + W K+W + +C L GH+ + +TV++ P
Sbjct: 234 ISYCHFSPN--SKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTVSLDP 291
Query: 478 DGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALCFSPN-RYWLCAAFGPSIKIWD 305
AS D LW L+ + + ++ H + + + P+ R+ + S ++WD
Sbjct: 292 KDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWD 351
Query: 304 LESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQV 143
LE++E EI++Q S +A+ DG G D RVW +
Sbjct: 352 LEAQE-------EILHQEGHSM----GVYDIAFHQDGSLAGTGGLDAFGRVWDL 394
Score = 41.5 bits (93), Expect = 0.003
Identities = 44/194 (22%), Positives = 76/194 (39%), Gaps = 9/194 (4%)
Frame = -2
Query: 697 KLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPI------IVSCGWDRTVKVWHLTNCK 536
KLW+ + +C GH+ V + F P + + SC D +VK+W L + +
Sbjct: 256 KLWS-VPDCNLLHTLRGHNTNVGAIVFHPKSTVSLDPKDVNLASCAADGSVKLWSLDSDE 314
Query: 535 LKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKH-LHTLDHNDIITALCFS 359
+ GH+ + V P G + D LWDL + LH H+ + + F
Sbjct: 315 PVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFH 374
Query: 358 PNRYWLCAAFGPSI--KIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTL 185
+ L G ++WDL + + L + + + +S +G +
Sbjct: 375 QDGS-LAGTGGLDAFGRVWDLRTGRCIMFLEGHL-----------KEIYGINFSPNGYHI 422
Query: 184 FAGYSDNTIRVWQV 143
G DNT +VW +
Sbjct: 423 ATGSGDNTCKVWDL 436
>AY572489-1|AAS78572.1| 521|Homo sapiens 60 kDa U4/U6
snRNP-specific spliceosomal protein protein.
Length = 521
Score = 69.7 bits (163), Expect = 1e-11
Identities = 54/189 (28%), Positives = 88/189 (46%), Gaps = 2/189 (1%)
Frame = -2
Query: 709 DKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLK 530
D ++KLW+ L + +GH+ V+ V + P+ + +C +DR+ ++W L +
Sbjct: 301 DGSVKLWS-LDSDEPVADIEGHTVRVARVMWHPS-GRFLGTTC-YDRSWRLWDLEAQEEI 357
Query: 529 INHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALCFSPN 353
++ GHS + + DGSL +GG D +WDL G+ + L+ H I + FSPN
Sbjct: 358 LHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPN 417
Query: 352 RYWLCAAFGP-SIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAG 176
Y + G + K+WDL + V + P N K +P G L G
Sbjct: 418 GYHIATGSGDNTCKVWDLRQRRCVYTI-PAHQNLVTGVKFEP---------IHGNFLLTG 467
Query: 175 YSDNTIRVW 149
DNT ++W
Sbjct: 468 AYDNTAKIW 476
Score = 53.6 bits (123), Expect = 7e-07
Identities = 32/98 (32%), Positives = 46/98 (46%), Gaps = 1/98 (1%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAE-CKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
GS D T K+W+ C YTI H + V+ V+F P H N +++ +D T K+W
Sbjct: 424 GSGDNTCKVWDLRQRRCVYTIP--AHQNLVTGVKFEPIHGN-FLLTGAYDNTAKIWTHPG 480
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLW 428
GH G + + +S DG L A+ D LW
Sbjct: 481 WSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLW 518
Score = 43.6 bits (98), Expect = 7e-04
Identities = 42/174 (24%), Positives = 75/174 (43%), Gaps = 10/174 (5%)
Frame = -2
Query: 634 VSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYL--------NTVTVSP 479
+S FSPN + ++ + W K+W + +C L GH+ + +TV++ P
Sbjct: 233 ISYCHFSPN--SKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTVSLDP 290
Query: 478 DGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALCFSPN-RYWLCAAFGPSIKIWD 305
AS D LW L+ + + ++ H + + + P+ R+ + S ++WD
Sbjct: 291 KDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWD 350
Query: 304 LESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQV 143
LE++E EI++Q S +A+ DG G D RVW +
Sbjct: 351 LEAQE-------EILHQEGHSM----GVYDIAFHQDGSLAGTGGLDAFGRVWDL 393
Score = 41.5 bits (93), Expect = 0.003
Identities = 44/194 (22%), Positives = 76/194 (39%), Gaps = 9/194 (4%)
Frame = -2
Query: 697 KLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPI------IVSCGWDRTVKVWHLTNCK 536
KLW+ + +C GH+ V + F P + + SC D +VK+W L + +
Sbjct: 255 KLWS-VPDCNLLHTLRGHNTNVGAIVFHPKSTVSLDPKDVNLASCAADGSVKLWSLDSDE 313
Query: 535 LKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKH-LHTLDHNDIITALCFS 359
+ GH+ + V P G + D LWDL + LH H+ + + F
Sbjct: 314 PVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFH 373
Query: 358 PNRYWLCAAFGPSI--KIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTL 185
+ L G ++WDL + + L + + + +S +G +
Sbjct: 374 QDGS-LAGTGGLDAFGRVWDLRTGRCIMFLEGHL-----------KEIYGINFSPNGYHI 421
Query: 184 FAGYSDNTIRVWQV 143
G DNT +VW +
Sbjct: 422 ATGSGDNTCKVWDL 435
>AL449305-8|CAI10969.1| 521|Homo sapiens PRP4 pre-mRNA processing
factor 4 homolog (yeast) protein.
Length = 521
Score = 69.7 bits (163), Expect = 1e-11
Identities = 54/189 (28%), Positives = 88/189 (46%), Gaps = 2/189 (1%)
Frame = -2
Query: 709 DKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLK 530
D ++KLW+ L + +GH+ V+ V + P+ + +C +DR+ ++W L +
Sbjct: 301 DGSVKLWS-LDSDEPVADIEGHTVRVARVMWHPS-GRFLGTTC-YDRSWRLWDLEAQEEI 357
Query: 529 INHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALCFSPN 353
++ GHS + + DGSL +GG D +WDL G+ + L+ H I + FSPN
Sbjct: 358 LHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPN 417
Query: 352 RYWLCAAFGP-SIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAG 176
Y + G + K+WDL + V + P N K +P G L G
Sbjct: 418 GYHIATGSGDNTCKVWDLRQRRCVYTI-PAHQNLVTGVKFEP---------IHGNFLLTG 467
Query: 175 YSDNTIRVW 149
DNT ++W
Sbjct: 468 AYDNTAKIW 476
Score = 53.6 bits (123), Expect = 7e-07
Identities = 32/98 (32%), Positives = 46/98 (46%), Gaps = 1/98 (1%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAE-CKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
GS D T K+W+ C YTI H + V+ V+F P H N +++ +D T K+W
Sbjct: 424 GSGDNTCKVWDLRQRRCVYTIP--AHQNLVTGVKFEPIHGN-FLLTGAYDNTAKIWTHPG 480
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLW 428
GH G + + +S DG L A+ D LW
Sbjct: 481 WSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLW 518
Score = 43.6 bits (98), Expect = 7e-04
Identities = 42/174 (24%), Positives = 75/174 (43%), Gaps = 10/174 (5%)
Frame = -2
Query: 634 VSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYL--------NTVTVSP 479
+S FSPN + ++ + W K+W + +C L GH+ + +TV++ P
Sbjct: 233 ISYCHFSPN--SKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTVSLDP 290
Query: 478 DGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALCFSPN-RYWLCAAFGPSIKIWD 305
AS D LW L+ + + ++ H + + + P+ R+ + S ++WD
Sbjct: 291 KDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWD 350
Query: 304 LESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQV 143
LE++E EI++Q S +A+ DG G D RVW +
Sbjct: 351 LEAQE-------EILHQEGHSM----GVYDIAFHQDGSLAGTGGLDAFGRVWDL 393
Score = 41.5 bits (93), Expect = 0.003
Identities = 44/194 (22%), Positives = 76/194 (39%), Gaps = 9/194 (4%)
Frame = -2
Query: 697 KLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPI------IVSCGWDRTVKVWHLTNCK 536
KLW+ + +C GH+ V + F P + + SC D +VK+W L + +
Sbjct: 255 KLWS-VPDCNLLHTLRGHNTNVGAIVFHPKSTVSLDPKDVNLASCAADGSVKLWSLDSDE 313
Query: 535 LKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKH-LHTLDHNDIITALCFS 359
+ GH+ + V P G + D LWDL + LH H+ + + F
Sbjct: 314 PVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFH 373
Query: 358 PNRYWLCAAFGPSI--KIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTL 185
+ L G ++WDL + + L + + + +S +G +
Sbjct: 374 QDGS-LAGTGGLDAFGRVWDLRTGRCIMFLEGHL-----------KEIYGINFSPNGYHI 421
Query: 184 FAGYSDNTIRVWQV 143
G DNT +VW +
Sbjct: 422 ATGSGDNTCKVWDL 435
>AL449305-7|CAI10968.1| 522|Homo sapiens PRP4 pre-mRNA processing
factor 4 homolog (yeast) protein.
Length = 522
Score = 69.7 bits (163), Expect = 1e-11
Identities = 54/189 (28%), Positives = 88/189 (46%), Gaps = 2/189 (1%)
Frame = -2
Query: 709 DKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLK 530
D ++KLW+ L + +GH+ V+ V + P+ + +C +DR+ ++W L +
Sbjct: 302 DGSVKLWS-LDSDEPVADIEGHTVRVARVMWHPS-GRFLGTTC-YDRSWRLWDLEAQEEI 358
Query: 529 INHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALCFSPN 353
++ GHS + + DGSL +GG D +WDL G+ + L+ H I + FSPN
Sbjct: 359 LHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPN 418
Query: 352 RYWLCAAFGP-SIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAG 176
Y + G + K+WDL + V + P N K +P G L G
Sbjct: 419 GYHIATGSGDNTCKVWDLRQRRCVYTI-PAHQNLVTGVKFEP---------IHGNFLLTG 468
Query: 175 YSDNTIRVW 149
DNT ++W
Sbjct: 469 AYDNTAKIW 477
Score = 53.6 bits (123), Expect = 7e-07
Identities = 32/98 (32%), Positives = 46/98 (46%), Gaps = 1/98 (1%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAE-CKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
GS D T K+W+ C YTI H + V+ V+F P H N +++ +D T K+W
Sbjct: 425 GSGDNTCKVWDLRQRRCVYTIP--AHQNLVTGVKFEPIHGN-FLLTGAYDNTAKIWTHPG 481
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLW 428
GH G + + +S DG L A+ D LW
Sbjct: 482 WSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLW 519
Score = 43.6 bits (98), Expect = 7e-04
Identities = 42/174 (24%), Positives = 75/174 (43%), Gaps = 10/174 (5%)
Frame = -2
Query: 634 VSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYL--------NTVTVSP 479
+S FSPN + ++ + W K+W + +C L GH+ + +TV++ P
Sbjct: 234 ISYCHFSPN--SKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTVSLDP 291
Query: 478 DGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALCFSPN-RYWLCAAFGPSIKIWD 305
AS D LW L+ + + ++ H + + + P+ R+ + S ++WD
Sbjct: 292 KDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWD 351
Query: 304 LESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQV 143
LE++E EI++Q S +A+ DG G D RVW +
Sbjct: 352 LEAQE-------EILHQEGHSM----GVYDIAFHQDGSLAGTGGLDAFGRVWDL 394
Score = 41.5 bits (93), Expect = 0.003
Identities = 44/194 (22%), Positives = 76/194 (39%), Gaps = 9/194 (4%)
Frame = -2
Query: 697 KLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPI------IVSCGWDRTVKVWHLTNCK 536
KLW+ + +C GH+ V + F P + + SC D +VK+W L + +
Sbjct: 256 KLWS-VPDCNLLHTLRGHNTNVGAIVFHPKSTVSLDPKDVNLASCAADGSVKLWSLDSDE 314
Query: 535 LKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKH-LHTLDHNDIITALCFS 359
+ GH+ + V P G + D LWDL + LH H+ + + F
Sbjct: 315 PVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFH 374
Query: 358 PNRYWLCAAFGPSI--KIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTL 185
+ L G ++WDL + + L + + + +S +G +
Sbjct: 375 QDGS-LAGTGGLDAFGRVWDLRTGRCIMFLEGHL-----------KEIYGINFSPNGYHI 422
Query: 184 FAGYSDNTIRVWQV 143
G DNT +VW +
Sbjct: 423 ATGSGDNTCKVWDL 436
>AF016369-1|AAC51925.1| 522|Homo sapiens U4/U6 small nuclear
ribonucleoprotein hPrp4 protein.
Length = 522
Score = 69.7 bits (163), Expect = 1e-11
Identities = 54/189 (28%), Positives = 88/189 (46%), Gaps = 2/189 (1%)
Frame = -2
Query: 709 DKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLK 530
D ++KLW+ L + +GH+ V+ V + P+ + +C +DR+ ++W L +
Sbjct: 302 DGSVKLWS-LDSDEPVADIEGHTVRVARVMWHPS-GRFLGTTC-YDRSWRLWDLEAQEEI 358
Query: 529 INHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALCFSPN 353
++ GHS + + DGSL +GG D +WDL G+ + L+ H I + FSPN
Sbjct: 359 LHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPN 418
Query: 352 RYWLCAAFGP-SIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAG 176
Y + G + K+WDL + V + P N K +P G L G
Sbjct: 419 GYHIATGSGDNTCKVWDLRQRRCVYTI-PAHQNLVTGVKFEP---------IHGNFLLTG 468
Query: 175 YSDNTIRVW 149
DNT ++W
Sbjct: 469 AYDNTAKIW 477
Score = 53.6 bits (123), Expect = 7e-07
Identities = 32/98 (32%), Positives = 46/98 (46%), Gaps = 1/98 (1%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAE-CKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
GS D T K+W+ C YTI H + V+ V+F P H N +++ +D T K+W
Sbjct: 425 GSGDNTCKVWDLRQRRCVYTIP--AHQNLVTGVKFEPIHGN-FLLTGAYDNTAKIWTHPG 481
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLW 428
GH G + + +S DG L A+ D LW
Sbjct: 482 WSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLW 519
Score = 43.6 bits (98), Expect = 7e-04
Identities = 42/174 (24%), Positives = 75/174 (43%), Gaps = 10/174 (5%)
Frame = -2
Query: 634 VSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYL--------NTVTVSP 479
+S FSPN + ++ + W K+W + +C L GH+ + +TV++ P
Sbjct: 234 ISYCHFSPN--SKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTVSLDP 291
Query: 478 DGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALCFSPN-RYWLCAAFGPSIKIWD 305
AS D LW L+ + + ++ H + + + P+ R+ + S ++WD
Sbjct: 292 KDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWD 351
Query: 304 LESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQV 143
LE++E EI++Q S +A+ DG G D RVW +
Sbjct: 352 LEAQE-------EILHQEGHSM----GVYDIAFHQDGSLAGTGGLDAFGRVWDL 394
Score = 41.5 bits (93), Expect = 0.003
Identities = 44/194 (22%), Positives = 76/194 (39%), Gaps = 9/194 (4%)
Frame = -2
Query: 697 KLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPI------IVSCGWDRTVKVWHLTNCK 536
KLW+ + +C GH+ V + F P + + SC D +VK+W L + +
Sbjct: 256 KLWS-VPDCNLLHTLRGHNTNVGAIVFHPKSTVSLDPKDVNLASCAADGSVKLWSLDSDE 314
Query: 535 LKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKH-LHTLDHNDIITALCFS 359
+ GH+ + V P G + D LWDL + LH H+ + + F
Sbjct: 315 PVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFH 374
Query: 358 PNRYWLCAAFGPSI--KIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTL 185
+ L G ++WDL + + L + + + +S +G +
Sbjct: 375 QDGS-LAGTGGLDAFGRVWDLRTGRCIMFLEGHL-----------KEIYGINFSPNGYHI 422
Query: 184 FAGYSDNTIRVWQV 143
G DNT +VW +
Sbjct: 423 ATGSGDNTCKVWDL 436
>AB209797-1|BAD93034.1| 537|Homo sapiens PRPF4 protein variant
protein.
Length = 537
Score = 69.7 bits (163), Expect = 1e-11
Identities = 54/189 (28%), Positives = 88/189 (46%), Gaps = 2/189 (1%)
Frame = -2
Query: 709 DKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLK 530
D ++KLW+ L + +GH+ V+ V + P+ + +C +DR+ ++W L +
Sbjct: 317 DGSVKLWS-LDSDEPVADIEGHTVRVARVMWHPS-GRFLGTTC-YDRSWRLWDLEAQEEI 373
Query: 529 INHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALCFSPN 353
++ GHS + + DGSL +GG D +WDL G+ + L+ H I + FSPN
Sbjct: 374 LHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPN 433
Query: 352 RYWLCAAFGP-SIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAG 176
Y + G + K+WDL + V + P N K +P G L G
Sbjct: 434 GYHIATGSGDNTCKVWDLRQRRCVYTI-PAHQNLVTGVKFEP---------IHGNFLLTG 483
Query: 175 YSDNTIRVW 149
DNT ++W
Sbjct: 484 AYDNTAKIW 492
Score = 53.6 bits (123), Expect = 7e-07
Identities = 32/98 (32%), Positives = 46/98 (46%), Gaps = 1/98 (1%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAE-CKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
GS D T K+W+ C YTI H + V+ V+F P H N +++ +D T K+W
Sbjct: 440 GSGDNTCKVWDLRQRRCVYTIP--AHQNLVTGVKFEPIHGN-FLLTGAYDNTAKIWTHPG 496
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLW 428
GH G + + +S DG L A+ D LW
Sbjct: 497 WSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLW 534
Score = 43.6 bits (98), Expect = 7e-04
Identities = 42/174 (24%), Positives = 75/174 (43%), Gaps = 10/174 (5%)
Frame = -2
Query: 634 VSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYL--------NTVTVSP 479
+S FSPN + ++ + W K+W + +C L GH+ + +TV++ P
Sbjct: 249 ISYCHFSPN--SKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTVSLDP 306
Query: 478 DGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALCFSPN-RYWLCAAFGPSIKIWD 305
AS D LW L+ + + ++ H + + + P+ R+ + S ++WD
Sbjct: 307 KDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWD 366
Query: 304 LESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQV 143
LE++E EI++Q S +A+ DG G D RVW +
Sbjct: 367 LEAQE-------EILHQEGHSM----GVYDIAFHQDGSLAGTGGLDAFGRVWDL 409
Score = 41.5 bits (93), Expect = 0.003
Identities = 44/194 (22%), Positives = 76/194 (39%), Gaps = 9/194 (4%)
Frame = -2
Query: 697 KLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPI------IVSCGWDRTVKVWHLTNCK 536
KLW+ + +C GH+ V + F P + + SC D +VK+W L + +
Sbjct: 271 KLWS-VPDCNLLHTLRGHNTNVGAIVFHPKSTVSLDPKDVNLASCAADGSVKLWSLDSDE 329
Query: 535 LKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKH-LHTLDHNDIITALCFS 359
+ GH+ + V P G + D LWDL + LH H+ + + F
Sbjct: 330 PVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFH 389
Query: 358 PNRYWLCAAFGPSI--KIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTL 185
+ L G ++WDL + + L + + + +S +G +
Sbjct: 390 QDGS-LAGTGGLDAFGRVWDLRTGRCIMFLEGHL-----------KEIYGINFSPNGYHI 437
Query: 184 FAGYSDNTIRVWQV 143
G DNT +VW +
Sbjct: 438 ATGSGDNTCKVWDL 451
>BC012075-1|AAH12075.1| 485|Homo sapiens notchless homolog 1
(Drosophila) protein.
Length = 485
Score = 69.3 bits (162), Expect = 1e-11
Identities = 58/191 (30%), Positives = 87/191 (45%), Gaps = 8/191 (4%)
Frame = -2
Query: 694 LWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLG 515
++ A + T +GHS+ V V FSP + S D TV+ W L+ G
Sbjct: 97 IFRVRAVTRCTSSLEGHSEAVISVAFSPT--GKYLASGSGDTTVRFWDLSTETPHFTCKG 154
Query: 514 HSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHL-HTL-DHNDIITALCFSP----- 356
H ++ +++ SPDG ASG K+ + +LWD + GK + TL H+ IT L + P
Sbjct: 155 HRHWVLSISWSPDGKKLASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANP 214
Query: 355 -NRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFA 179
RY ++ S++IWD + L T T C L W DG L++
Sbjct: 215 ECRYVASSSKDGSVRIWDTTAGRCERIL---------TGHTQSVTC--LRWGGDG-LLYS 262
Query: 178 GYSDNTIRVWQ 146
D TI+VW+
Sbjct: 263 ASQDRTIKVWR 273
Score = 60.9 bits (141), Expect = 4e-09
Identities = 58/196 (29%), Positives = 87/196 (44%), Gaps = 5/196 (2%)
Frame = -2
Query: 715 SRDKTIKLWNTL--AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
S+D+TIK+W C+ T+Q GH WV+ + S ++A + +V L
Sbjct: 264 SQDRTIKVWRAHDGVLCR-TLQ--GHGHWVNTMALSTDYALRTGAFEPAEASVNPQDLQG 320
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWD-LNDGKHLHTLD-HNDIITAL 368
++ S Y N V L SG D LW D K L + H +I +
Sbjct: 321 SLQELKERALSRY-NLVRGQGPERL-VSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQV 378
Query: 367 CFSPN-RYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQ 191
FSP+ R A+F SIK+WD + + + LR + Q +AWS D +
Sbjct: 379 LFSPDSRIVASASFDKSIKLWDGRTGKYLASLRGHVAAVYQ-----------IAWSADSR 427
Query: 190 TLFAGYSDNTIRVWQV 143
L +G SD+T++VW V
Sbjct: 428 LLVSGSSDSTLKVWDV 443
Score = 60.5 bits (140), Expect = 6e-09
Identities = 40/152 (26%), Positives = 73/152 (48%), Gaps = 3/152 (1%)
Frame = -2
Query: 592 IVSCGWDRTVKVWHLTNCKLKINHL-GHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLND 416
+VS D T+ +W K + + GH +N V SPD + AS D LWD
Sbjct: 344 LVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRT 403
Query: 415 GKHLHTL-DHNDIITALCFS-PNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTS 242
GK+L +L H + + +S +R + + ++K+WD++++++ +L
Sbjct: 404 GKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDL---------PG 454
Query: 241 KTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQ 146
D + ++ WS DGQ + +G D +R+W+
Sbjct: 455 HAD--EVYAVDWSPDGQRVASGGKDKCLRIWR 484
Score = 56.8 bits (131), Expect = 7e-08
Identities = 36/123 (29%), Positives = 59/123 (47%), Gaps = 1/123 (0%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
GS D T+ LW+ + K + GH ++ V FSP+ + I+ S +D+++K+W
Sbjct: 347 GSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPD--SRIVASASFDKSIKLWDGRTG 404
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCF 362
K + GH + + S D L SG D +WD+ K L H D + A+ +
Sbjct: 405 KYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDW 464
Query: 361 SPN 353
SP+
Sbjct: 465 SPD 467
Score = 55.6 bits (128), Expect = 2e-07
Identities = 36/96 (37%), Positives = 51/96 (53%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK 536
S DK+IKLW+ KY GH V + +S + + ++VS D T+KVW + K
Sbjct: 391 SFDKSIKLWDGRTG-KYLASLRGHVAAVYQIAWSAD--SRLLVSGSSDSTLKVWDVKAQK 447
Query: 535 LKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLW 428
L ++ GH+ + V SPDG ASGGKD +W
Sbjct: 448 LAMDLPGHADEVYAVDWSPDGQRVASGGKDKCLRIW 483
Score = 47.6 bits (108), Expect = 4e-05
Identities = 26/84 (30%), Positives = 48/84 (57%), Gaps = 1/84 (1%)
Frame = -2
Query: 715 SRDKTIKLWNTLA-ECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
S+D ++++W+T A C+ + GH+ V+C+R+ + ++ S DRT+KVW +
Sbjct: 223 SKDGSVRIWDTTAGRCERILT--GHTQSVTCLRWG---GDGLLYSASQDRTIKVWRAHDG 277
Query: 538 KLKINHLGHSGYLNTVTVSPDGSL 467
L GH ++NT+ +S D +L
Sbjct: 278 VLCRTLQGHGHWVNTMALSTDYAL 301
Score = 36.3 bits (80), Expect = 0.11
Identities = 23/85 (27%), Positives = 41/85 (48%), Gaps = 1/85 (1%)
Frame = -2
Query: 391 HNDIITALCFSPNRYWLCAAFGPS-IKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLS 215
H++ + ++ FSP +L + G + ++ WDL ++ P T K LS
Sbjct: 113 HSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTET------PHF-----TCKGHRHWVLS 161
Query: 214 LAWSTDGQTLFAGYSDNTIRVWQVS 140
++WS DG+ L +G + I +W S
Sbjct: 162 ISWSPDGKKLASGCKNGQILLWDPS 186
>BC002884-1|AAH02884.2| 484|Homo sapiens NLE1 protein protein.
Length = 484
Score = 69.3 bits (162), Expect = 1e-11
Identities = 58/191 (30%), Positives = 87/191 (45%), Gaps = 8/191 (4%)
Frame = -2
Query: 694 LWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLG 515
++ A + T +GHS+ V V FSP + S D TV+ W L+ G
Sbjct: 96 IFRVRAVTRCTSSLEGHSEAVISVAFSPT--GKYLASGSGDTTVRFWDLSTETPHFTCKG 153
Query: 514 HSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHL-HTL-DHNDIITALCFSP----- 356
H ++ +++ SPDG ASG K+ + +LWD + GK + TL H+ IT L + P
Sbjct: 154 HRHWVLSISWSPDGKKLASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANP 213
Query: 355 -NRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFA 179
RY ++ S++IWD + L T T C L W DG L++
Sbjct: 214 ECRYVASSSKDGSVRIWDTTAGRCERIL---------TGHTQSVTC--LRWGGDG-LLYS 261
Query: 178 GYSDNTIRVWQ 146
D TI+VW+
Sbjct: 262 ASQDRTIKVWR 272
Score = 60.9 bits (141), Expect = 4e-09
Identities = 58/196 (29%), Positives = 87/196 (44%), Gaps = 5/196 (2%)
Frame = -2
Query: 715 SRDKTIKLWNTL--AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
S+D+TIK+W C+ T+Q GH WV+ + S ++A + +V L
Sbjct: 263 SQDRTIKVWRAHDGVLCR-TLQ--GHGHWVNTMALSTDYALRTGAFEPAEASVNPQDLQG 319
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWD-LNDGKHLHTLD-HNDIITAL 368
++ S Y N V L SG D LW D K L + H +I +
Sbjct: 320 SLQELKERALSRY-NLVRGQGPERL-VSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQV 377
Query: 367 CFSPN-RYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQ 191
FSP+ R A+F SIK+WD + + + LR + Q +AWS D +
Sbjct: 378 LFSPDSRIVASASFDKSIKLWDGRTGKYLASLRGHVAAVYQ-----------IAWSADSR 426
Query: 190 TLFAGYSDNTIRVWQV 143
L +G SD+T++VW V
Sbjct: 427 LLVSGSSDSTLKVWDV 442
Score = 60.5 bits (140), Expect = 6e-09
Identities = 40/152 (26%), Positives = 73/152 (48%), Gaps = 3/152 (1%)
Frame = -2
Query: 592 IVSCGWDRTVKVWHLTNCKLKINHL-GHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLND 416
+VS D T+ +W K + + GH +N V SPD + AS D LWD
Sbjct: 343 LVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRT 402
Query: 415 GKHLHTL-DHNDIITALCFS-PNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTS 242
GK+L +L H + + +S +R + + ++K+WD++++++ +L
Sbjct: 403 GKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDL---------PG 453
Query: 241 KTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQ 146
D + ++ WS DGQ + +G D +R+W+
Sbjct: 454 HAD--EVYAVDWSPDGQRVASGGKDKCLRIWR 483
Score = 56.8 bits (131), Expect = 7e-08
Identities = 36/123 (29%), Positives = 59/123 (47%), Gaps = 1/123 (0%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
GS D T+ LW+ + K + GH ++ V FSP+ + I+ S +D+++K+W
Sbjct: 346 GSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPD--SRIVASASFDKSIKLWDGRTG 403
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCF 362
K + GH + + S D L SG D +WD+ K L H D + A+ +
Sbjct: 404 KYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDW 463
Query: 361 SPN 353
SP+
Sbjct: 464 SPD 466
Score = 55.6 bits (128), Expect = 2e-07
Identities = 36/96 (37%), Positives = 51/96 (53%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK 536
S DK+IKLW+ KY GH V + +S + + ++VS D T+KVW + K
Sbjct: 390 SFDKSIKLWDGRTG-KYLASLRGHVAAVYQIAWSAD--SRLLVSGSSDSTLKVWDVKAQK 446
Query: 535 LKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLW 428
L ++ GH+ + V SPDG ASGGKD +W
Sbjct: 447 LAMDLPGHADEVYAVDWSPDGQRVASGGKDKCLRIW 482
Score = 47.6 bits (108), Expect = 4e-05
Identities = 26/84 (30%), Positives = 48/84 (57%), Gaps = 1/84 (1%)
Frame = -2
Query: 715 SRDKTIKLWNTLA-ECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
S+D ++++W+T A C+ + GH+ V+C+R+ + ++ S DRT+KVW +
Sbjct: 222 SKDGSVRIWDTTAGRCERILT--GHTQSVTCLRWG---GDGLLYSASQDRTIKVWRAHDG 276
Query: 538 KLKINHLGHSGYLNTVTVSPDGSL 467
L GH ++NT+ +S D +L
Sbjct: 277 VLCRTLQGHGHWVNTMALSTDYAL 300
Score = 36.3 bits (80), Expect = 0.11
Identities = 23/85 (27%), Positives = 41/85 (48%), Gaps = 1/85 (1%)
Frame = -2
Query: 391 HNDIITALCFSPNRYWLCAAFGPS-IKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLS 215
H++ + ++ FSP +L + G + ++ WDL ++ P T K LS
Sbjct: 112 HSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTET------PHF-----TCKGHRHWVLS 160
Query: 214 LAWSTDGQTLFAGYSDNTIRVWQVS 140
++WS DG+ L +G + I +W S
Sbjct: 161 ISWSPDGKKLASGCKNGQILLWDPS 185
>AK001320-1|BAA91621.1| 485|Homo sapiens protein ( Homo sapiens
cDNA FLJ10458 fis, clone NT2RP1001457, highly similar to
Homo sapiens partial mRNA for beta-transducin family
protein. ).
Length = 485
Score = 69.3 bits (162), Expect = 1e-11
Identities = 58/191 (30%), Positives = 87/191 (45%), Gaps = 8/191 (4%)
Frame = -2
Query: 694 LWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLG 515
++ A + T +GHS+ V V FSP + S D TV+ W L+ G
Sbjct: 97 IFRVRAVTRCTSSLEGHSEAVISVAFSPT--GKYLASGSGDTTVRFWDLSTETPHFTCKG 154
Query: 514 HSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHL-HTL-DHNDIITALCFSP----- 356
H ++ +++ SPDG ASG K+ + +LWD + GK + TL H+ IT L + P
Sbjct: 155 HRHWVLSISWSPDGKKLASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANP 214
Query: 355 -NRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFA 179
RY ++ S++IWD + L T T C L W DG L++
Sbjct: 215 ECRYVASSSKDGSVRIWDTTAGRCERIL---------TGHTQSVTC--LRWGGDG-LLYS 262
Query: 178 GYSDNTIRVWQ 146
D TI+VW+
Sbjct: 263 ASQDRTIKVWR 273
Score = 60.9 bits (141), Expect = 4e-09
Identities = 58/196 (29%), Positives = 87/196 (44%), Gaps = 5/196 (2%)
Frame = -2
Query: 715 SRDKTIKLWNTL--AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
S+D+TIK+W C+ T+Q GH WV+ + S ++A + +V L
Sbjct: 264 SQDRTIKVWRAHDGVLCR-TLQ--GHGHWVNTMALSTDYALRTGAFEPAEASVNPQDLQG 320
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWD-LNDGKHLHTLD-HNDIITAL 368
++ S Y N V L SG D LW D K L + H +I +
Sbjct: 321 SLQELKERALSRY-NLVRGQGPERL-VSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQV 378
Query: 367 CFSPN-RYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQ 191
FSP+ R A+F SIK+WD + + + LR + Q +AWS D +
Sbjct: 379 LFSPDSRIVASASFDKSIKLWDGRTGKYLASLRGHVAAVYQ-----------IAWSADSR 427
Query: 190 TLFAGYSDNTIRVWQV 143
L +G SD+T++VW V
Sbjct: 428 LLVSGSSDSTLKVWDV 443
Score = 60.5 bits (140), Expect = 6e-09
Identities = 40/152 (26%), Positives = 73/152 (48%), Gaps = 3/152 (1%)
Frame = -2
Query: 592 IVSCGWDRTVKVWHLTNCKLKINHL-GHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLND 416
+VS D T+ +W K + + GH +N V SPD + AS D LWD
Sbjct: 344 LVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRT 403
Query: 415 GKHLHTL-DHNDIITALCFS-PNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTS 242
GK+L +L H + + +S +R + + ++K+WD++++++ +L
Sbjct: 404 GKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDL---------PG 454
Query: 241 KTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQ 146
D + ++ WS DGQ + +G D +R+W+
Sbjct: 455 HAD--EVYAVDWSPDGQRVASGGKDKCLRIWR 484
Score = 56.8 bits (131), Expect = 7e-08
Identities = 36/123 (29%), Positives = 59/123 (47%), Gaps = 1/123 (0%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
GS D T+ LW+ + K + GH ++ V FSP+ + I+ S +D+++K+W
Sbjct: 347 GSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPD--SRIVASASFDKSIKLWDGRTG 404
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCF 362
K + GH + + S D L SG D +WD+ K L H D + A+ +
Sbjct: 405 KYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDW 464
Query: 361 SPN 353
SP+
Sbjct: 465 SPD 467
Score = 55.6 bits (128), Expect = 2e-07
Identities = 36/96 (37%), Positives = 51/96 (53%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK 536
S DK+IKLW+ KY GH V + +S + + ++VS D T+KVW + K
Sbjct: 391 SFDKSIKLWDGRTG-KYLASLRGHVAAVYQIAWSAD--SRLLVSGSSDSTLKVWDVKAQK 447
Query: 535 LKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLW 428
L ++ GH+ + V SPDG ASGGKD +W
Sbjct: 448 LAMDLPGHADEVYAVDWSPDGQRVASGGKDKCLRIW 483
Score = 47.6 bits (108), Expect = 4e-05
Identities = 26/84 (30%), Positives = 48/84 (57%), Gaps = 1/84 (1%)
Frame = -2
Query: 715 SRDKTIKLWNTLA-ECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
S+D ++++W+T A C+ + GH+ V+C+R+ + ++ S DRT+KVW +
Sbjct: 223 SKDGSVRIWDTTAGRCERILT--GHTQSVTCLRWG---GDGLLYSASQDRTIKVWRAHDG 277
Query: 538 KLKINHLGHSGYLNTVTVSPDGSL 467
L GH ++NT+ +S D +L
Sbjct: 278 VLCRTLQGHGHWVNTMALSTDYAL 301
Score = 36.3 bits (80), Expect = 0.11
Identities = 23/85 (27%), Positives = 41/85 (48%), Gaps = 1/85 (1%)
Frame = -2
Query: 391 HNDIITALCFSPNRYWLCAAFGPS-IKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLS 215
H++ + ++ FSP +L + G + ++ WDL ++ P T K LS
Sbjct: 113 HSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTET------PHF-----TCKGHRHWVLS 161
Query: 214 LAWSTDGQTLFAGYSDNTIRVWQVS 140
++WS DG+ L +G + I +W S
Sbjct: 162 ISWSPDGKKLASGCKNGQILLWDPS 186
>AB209111-1|BAD92348.1| 487|Homo sapiens Notchless gene homolog
variant protein.
Length = 487
Score = 69.3 bits (162), Expect = 1e-11
Identities = 58/191 (30%), Positives = 87/191 (45%), Gaps = 8/191 (4%)
Frame = -2
Query: 694 LWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLG 515
++ A + T +GHS+ V V FSP + S D TV+ W L+ G
Sbjct: 99 IFRVRAVTRCTSSLEGHSEAVISVAFSPT--GKYLASGSGDTTVRFWDLSTETPHFTCKG 156
Query: 514 HSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHL-HTL-DHNDIITALCFSP----- 356
H ++ +++ SPDG ASG K+ + +LWD + GK + TL H+ IT L + P
Sbjct: 157 HRHWVLSISWSPDGKKLASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANP 216
Query: 355 -NRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFA 179
RY ++ S++IWD + L T T C L W DG L++
Sbjct: 217 ECRYVASSSKDGSVRIWDTTAGRCERIL---------TGHTQSVTC--LRWGGDG-LLYS 264
Query: 178 GYSDNTIRVWQ 146
D TI+VW+
Sbjct: 265 ASQDRTIKVWR 275
Score = 60.5 bits (140), Expect = 6e-09
Identities = 58/196 (29%), Positives = 87/196 (44%), Gaps = 5/196 (2%)
Frame = -2
Query: 715 SRDKTIKLWNTL--AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
S+D+TIK+W C+ T+Q GH WV+ + S ++A + +V L
Sbjct: 266 SQDRTIKVWRAHDGVLCR-TLQ--GHGHWVNTMALSTDYALRTGAFEPAEASVNPQDLQG 322
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWD-LNDGKHLHTLD-HNDIITAL 368
++ S Y N V L SG D LW D K L + H +I +
Sbjct: 323 FLQELKERALSRY-NLVRGQGPERL-VSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQV 380
Query: 367 CFSPN-RYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQ 191
FSP+ R A+F SIK+WD + + + LR + Q +AWS D +
Sbjct: 381 LFSPDSRIVASASFDKSIKLWDGRTGKYLASLRGHVAAVYQ-----------IAWSADSR 429
Query: 190 TLFAGYSDNTIRVWQV 143
L +G SD+T++VW V
Sbjct: 430 LLVSGSSDSTLKVWDV 445
Score = 60.5 bits (140), Expect = 6e-09
Identities = 40/152 (26%), Positives = 73/152 (48%), Gaps = 3/152 (1%)
Frame = -2
Query: 592 IVSCGWDRTVKVWHLTNCKLKINHL-GHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLND 416
+VS D T+ +W K + + GH +N V SPD + AS D LWD
Sbjct: 346 LVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRT 405
Query: 415 GKHLHTL-DHNDIITALCFS-PNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTS 242
GK+L +L H + + +S +R + + ++K+WD++++++ +L
Sbjct: 406 GKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDL---------PG 456
Query: 241 KTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQ 146
D + ++ WS DGQ + +G D +R+W+
Sbjct: 457 HAD--EVYAVDWSPDGQRVASGGKDKCLRIWR 486
Score = 56.8 bits (131), Expect = 7e-08
Identities = 36/123 (29%), Positives = 59/123 (47%), Gaps = 1/123 (0%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
GS D T+ LW+ + K + GH ++ V FSP+ + I+ S +D+++K+W
Sbjct: 349 GSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPD--SRIVASASFDKSIKLWDGRTG 406
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCF 362
K + GH + + S D L SG D +WD+ K L H D + A+ +
Sbjct: 407 KYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDW 466
Query: 361 SPN 353
SP+
Sbjct: 467 SPD 469
Score = 55.6 bits (128), Expect = 2e-07
Identities = 36/96 (37%), Positives = 51/96 (53%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK 536
S DK+IKLW+ KY GH V + +S + + ++VS D T+KVW + K
Sbjct: 393 SFDKSIKLWDGRTG-KYLASLRGHVAAVYQIAWSAD--SRLLVSGSSDSTLKVWDVKAQK 449
Query: 535 LKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLW 428
L ++ GH+ + V SPDG ASGGKD +W
Sbjct: 450 LAMDLPGHADEVYAVDWSPDGQRVASGGKDKCLRIW 485
Score = 47.6 bits (108), Expect = 4e-05
Identities = 26/84 (30%), Positives = 48/84 (57%), Gaps = 1/84 (1%)
Frame = -2
Query: 715 SRDKTIKLWNTLA-ECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
S+D ++++W+T A C+ + GH+ V+C+R+ + ++ S DRT+KVW +
Sbjct: 225 SKDGSVRIWDTTAGRCERILT--GHTQSVTCLRWG---GDGLLYSASQDRTIKVWRAHDG 279
Query: 538 KLKINHLGHSGYLNTVTVSPDGSL 467
L GH ++NT+ +S D +L
Sbjct: 280 VLCRTLQGHGHWVNTMALSTDYAL 303
Score = 36.3 bits (80), Expect = 0.11
Identities = 23/85 (27%), Positives = 41/85 (48%), Gaps = 1/85 (1%)
Frame = -2
Query: 391 HNDIITALCFSPNRYWLCAAFGPS-IKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLS 215
H++ + ++ FSP +L + G + ++ WDL ++ P T K LS
Sbjct: 115 HSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTET------PHF-----TCKGHRHWVLS 163
Query: 214 LAWSTDGQTLFAGYSDNTIRVWQVS 140
++WS DG+ L +G + I +W S
Sbjct: 164 ISWSPDGKKLASGCKNGQILLWDPS 188
>AK127882-1|BAC87175.1| 369|Homo sapiens protein ( Homo sapiens
cDNA FLJ45988 fis, clone PUAEN2006639, weakly similar
to Vegetatible incompatibility protein HET-E-1. ).
Length = 369
Score = 68.9 bits (161), Expect = 2e-11
Identities = 40/150 (26%), Positives = 78/150 (52%), Gaps = 2/150 (1%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
GS D+T KLW++ + + + GH + V + F+ + + I +D+T K+W +
Sbjct: 110 GSYDRTCKLWDSASGEELNTLE-GHRNVVYAIAFNNPYGDKIATG-SFDKTCKLWSVETG 167
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCF 362
K GH+ + ++ +P +L A+G D A LWD+ +G+ ++TL H+ I +L F
Sbjct: 168 KCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQNGEEVYTLRGHSAEIISLSF 227
Query: 361 SPN-RYWLCAAFGPSIKIWDLESKEMVEEL 275
+ + + +F ++ +WD ++ V L
Sbjct: 228 NTSGDRIITGSFDHTVVVWDADTGRKVNIL 257
Score = 59.3 bits (137), Expect = 1e-08
Identities = 43/122 (35%), Positives = 63/122 (51%), Gaps = 3/122 (2%)
Frame = -2
Query: 718 GSRDKTIKLWNTL-AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
GS D T KLW+ E YT++ GHS + + F N + I++ +D TV VW
Sbjct: 195 GSMDTTAKLWDIQNGEEVYTLR--GHSAEIISLSF--NTSGDRIITGSFDHTVVVWDADT 250
Query: 541 CKLKINHL-GHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITAL 368
+ K+N L GH +++ + + D SL +G D LWD +GK + TL H+D I
Sbjct: 251 GR-KVNILIGHCAEISSASFNWDCSLILTGSMDKTCKLWDATNGKCVATLTGHDDEILDS 309
Query: 367 CF 362
CF
Sbjct: 310 CF 311
Score = 58.8 bits (136), Expect = 2e-08
Identities = 42/158 (26%), Positives = 72/158 (45%), Gaps = 4/158 (2%)
Frame = -2
Query: 610 NHANPIIVSCGWDRTVKVWHLTNCKLKINHL-GHSGYLNTVTVS-PDGSLCASGGKDMKA 437
N + ++ +DRT K+W + + ++N L GH + + + P G A+G D
Sbjct: 101 NKSGSCFITGSYDRTCKLWDSASGE-ELNTLEGHRNVVYAIAFNNPYGDKIATGSFDKTC 159
Query: 436 MLWDLNDGKHLHTL-DHNDIITALCFSPNRYWLCA-AFGPSIKIWDLESKEMVEELRPEI 263
LW + GK HT H I L F+P + + + K+WD+++ E V LR
Sbjct: 160 KLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQNGEEVYTLRGH- 218
Query: 262 INQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVW 149
+ +SL+++T G + G D+T+ VW
Sbjct: 219 ----------SAEIISLSFNTSGDRIITGSFDHTVVVW 246
Score = 33.9 bits (74), Expect = 0.59
Identities = 26/91 (28%), Positives = 37/91 (40%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
GS D T+ +W+ K I GH +S F N +I++ D+T K+W TN
Sbjct: 237 GSFDHTVVVWDADTGRKVNILI-GHCAEISSASF--NWDCSLILTGSMDKTCKLWDATNG 293
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKD 446
K GH + G L A+ D
Sbjct: 294 KCVATLTGHDDEILDSCFDYTGKLIATASAD 324
>AK098821-1|BAC05425.1| 415|Homo sapiens protein ( Homo sapiens
cDNA FLJ25955 fis, clone TST03904. ).
Length = 415
Score = 68.9 bits (161), Expect = 2e-11
Identities = 40/150 (26%), Positives = 78/150 (52%), Gaps = 2/150 (1%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
GS D+T KLW++ + + + GH + V + F+ + + I +D+T K+W +
Sbjct: 110 GSYDRTCKLWDSASGEELNTLE-GHRNVVYAIAFNNPYGDKIATG-SFDKTCKLWSVETG 167
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCF 362
K GH+ + ++ +P +L A+G D A LWD+ +G+ ++TL H+ I +L F
Sbjct: 168 KCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQNGEEVYTLRGHSAEIISLSF 227
Query: 361 SPN-RYWLCAAFGPSIKIWDLESKEMVEEL 275
+ + + +F ++ +WD ++ V L
Sbjct: 228 NTSGDRIITGSFDHTVVVWDADTGRKVNIL 257
Score = 66.1 bits (154), Expect = 1e-10
Identities = 56/194 (28%), Positives = 94/194 (48%), Gaps = 4/194 (2%)
Frame = -2
Query: 718 GSRDKTIKLWNTL-AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
GS D T KLW+ E YT++ GHS + + F N + I++ +D TV VW
Sbjct: 195 GSMDTTAKLWDIQNGEEVYTLR--GHSAEIISLSF--NTSGDRIITGSFDHTVVVWDADT 250
Query: 541 CKLKINHL-GHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITAL 368
+ K+N L GH +++ + + D SL +G D LWD +GK + TL H+D I
Sbjct: 251 GR-KVNILIGHCAEISSASFNWDCSLILTGSMDKTCKLWDATNGKCVATLTGHDDEILDS 309
Query: 367 CFS-PNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQ 191
CF + A+ + +I+ +++ + +L ++ + SK ++++ G
Sbjct: 310 CFDYTGKLIATASADGTARIFSAATRKCIAKLEG---HEGEISK--------ISFNPQGN 358
Query: 190 TLFAGYSDNTIRVW 149
L G SD T R+W
Sbjct: 359 HLLTGSSDKTARIW 372
Score = 60.1 bits (139), Expect = 8e-09
Identities = 39/140 (27%), Positives = 66/140 (47%), Gaps = 3/140 (2%)
Frame = -2
Query: 718 GSRDKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
GS DKT KLW+ T +C T+ GH D + F ++ +I + D T +++
Sbjct: 279 GSMDKTCKLWDATNGKCVATLT--GHDDEILDSCF--DYTGKLIATASADGTARIFSAAT 334
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALC 365
K GH G ++ ++ +P G+ +G D A +WD G+ L L+ H D I +
Sbjct: 335 RKCIAKLEGHEGEISKISFNPQGNHLLTGSSDKTARIWDAQTGQCLQVLEGHTDEIFSCA 394
Query: 364 FS-PNRYWLCAAFGPSIKIW 308
F+ + + G + +IW
Sbjct: 395 FNYKGNIVITGSKGNTCRIW 414
>BC000873-1|AAH00873.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 4 protein.
Length = 340
Score = 68.5 bits (160), Expect = 2e-11
Identities = 50/170 (29%), Positives = 81/170 (47%), Gaps = 3/170 (1%)
Frame = -2
Query: 649 GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGS 470
GH+ ++SC RF + + I+ S G D T +W + + GHSG + ++++SPD
Sbjct: 141 GHTGYLSCCRFLDD--SQIVTSSG-DTTCALWDIETAQQTTTFTGHSGDVMSLSLSPDMR 197
Query: 469 LCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCFSPNRY-WLCAAFGPSIKIWDLES 296
SG D + LWD+ DG + H I A+ F PN Y + + + +++DL +
Sbjct: 198 TFVSGACDASSKLWDIRDGMCRQSFTGHVSDINAVSFFPNGYAFATGSDDATCRLFDLRA 257
Query: 295 -KEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVW 149
+E++ II S+A+S G+ L AGY D VW
Sbjct: 258 DQELLLYSHDNII----------CGITSVAFSKSGRLLLAGYDDFNCNVW 297
>AF300648-1|AAG18442.1| 340|Homo sapiens guanine nucleotide binding
protein beta subunit 4 protein.
Length = 340
Score = 68.5 bits (160), Expect = 2e-11
Identities = 50/170 (29%), Positives = 81/170 (47%), Gaps = 3/170 (1%)
Frame = -2
Query: 649 GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGS 470
GH+ ++SC RF + + I+ S G D T +W + + GHSG + ++++SPD
Sbjct: 141 GHTGYLSCCRFLDD--SQIVTSSG-DTTCALWDIETAQQTTTFTGHSGDVMSLSLSPDMR 197
Query: 469 LCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCFSPNRY-WLCAAFGPSIKIWDLES 296
SG D + LWD+ DG + H I A+ F PN Y + + + +++DL +
Sbjct: 198 TFVSGACDASSKLWDIRDGMCRQSFTGHVSDINAVSFFPNGYAFATGSDDATCRLFDLRA 257
Query: 295 -KEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVW 149
+E++ II S+A+S G+ L AGY D VW
Sbjct: 258 DQELLLYSHDNII----------CGITSVAFSKSGRLLLAGYDDFNCNVW 297
>BC106004-1|AAI06005.1| 514|Homo sapiens pleiotropic regulator 1
(PRL1 homolog, Arabidopsis) protein.
Length = 514
Score = 68.1 bits (159), Expect = 3e-11
Identities = 43/141 (30%), Positives = 69/141 (48%), Gaps = 2/141 (1%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
GS D+TIK+W+ LA K + GH V V S +P + SCG D+ VK W L
Sbjct: 222 GSADRTIKIWD-LASGKLKLSLTGHISTVRGVIVSTR--SPYLFSCGEDKQVKCWDLEYN 278
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-H-NDIITALC 365
K+ ++ GH + + + P + + +D A +WD+ +HTL H N + T C
Sbjct: 279 KVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRC 338
Query: 364 FSPNRYWLCAAFGPSIKIWDL 302
+ + + +I++WDL
Sbjct: 339 QAAEPQIITGSHDTTIRLWDL 359
Score = 63.7 bits (148), Expect = 6e-10
Identities = 49/171 (28%), Positives = 70/171 (40%), Gaps = 2/171 (1%)
Frame = -2
Query: 649 GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGS 470
GH WV C+ P N V+ DRT+K+W L + KLK++ GH + V VS
Sbjct: 202 GHLGWVRCIAVEPG--NQWFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRSP 259
Query: 469 LCASGGKDMKAMLWDLNDGKHL-HTLDHNDIITALCFSPNRYWLCAAFGPS-IKIWDLES 296
S G+D + WDL K + H H + L P L S +IWD+ +
Sbjct: 260 YLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVRT 319
Query: 295 KEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQV 143
K V L T+ +C + + G D TIR+W +
Sbjct: 320 KASVHTL------SGHTNAVATVRCQAAE-----PQIITGSHDTTIRLWDL 359
Score = 59.7 bits (138), Expect = 1e-08
Identities = 46/192 (23%), Positives = 83/192 (43%), Gaps = 2/192 (1%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECK-YTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
SRD T ++W+ + +T+ GH++ V+ VR A P I++ D T+++W L
Sbjct: 307 SRDSTARIWDVRTKASVHTLS--GHTNAVATVRCQA--AEPQIITGSHDTTIRLWDLVAG 362
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALCF 362
K ++ H + V + P ASG D W DG + L HN II L
Sbjct: 363 KTRVTLTNHKKSVRAVVLHPRHYTFASGSPD-NIKQWKFPDGSFIQNLSGHNAIINTLTV 421
Query: 361 SPNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLF 182
+ + + A ++ +WD + + + + + S++ C A+ L
Sbjct: 422 NSDGVLVSGADNGTMHLWDWRTGYNFQRVHAAVQPGSLDSESGIFAC---AFDQSESRLL 478
Query: 181 AGYSDNTIRVWQ 146
+D TI+V++
Sbjct: 479 TAEADKTIKVYR 490
>BC020786-1|AAH20786.1| 505|Homo sapiens PLRG1 protein protein.
Length = 505
Score = 68.1 bits (159), Expect = 3e-11
Identities = 43/141 (30%), Positives = 69/141 (48%), Gaps = 2/141 (1%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
GS D+TIK+W+ LA K + GH V V S +P + SCG D+ VK W L
Sbjct: 213 GSADRTIKIWD-LASGKLKLSLTGHISTVRGVIVSTR--SPYLFSCGEDKQVKCWDLEYN 269
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-H-NDIITALC 365
K+ ++ GH + + + P + + +D A +WD+ +HTL H N + T C
Sbjct: 270 KVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRC 329
Query: 364 FSPNRYWLCAAFGPSIKIWDL 302
+ + + +I++WDL
Sbjct: 330 QAAEPQIITGSHDTTIRLWDL 350
Score = 63.7 bits (148), Expect = 6e-10
Identities = 49/171 (28%), Positives = 70/171 (40%), Gaps = 2/171 (1%)
Frame = -2
Query: 649 GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGS 470
GH WV C+ P N V+ DRT+K+W L + KLK++ GH + V VS
Sbjct: 193 GHLGWVRCIAVEPG--NQWFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRSP 250
Query: 469 LCASGGKDMKAMLWDLNDGKHL-HTLDHNDIITALCFSPNRYWLCAAFGPS-IKIWDLES 296
S G+D + WDL K + H H + L P L S +IWD+ +
Sbjct: 251 YLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVRT 310
Query: 295 KEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQV 143
K V L T+ +C + + G D TIR+W +
Sbjct: 311 KASVHTL------SGHTNAVATVRCQAAE-----PQIITGSHDTTIRLWDL 350
Score = 59.7 bits (138), Expect = 1e-08
Identities = 46/192 (23%), Positives = 83/192 (43%), Gaps = 2/192 (1%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECK-YTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
SRD T ++W+ + +T+ GH++ V+ VR A P I++ D T+++W L
Sbjct: 298 SRDSTARIWDVRTKASVHTLS--GHTNAVATVRCQA--AEPQIITGSHDTTIRLWDLVAG 353
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALCF 362
K ++ H + V + P ASG D W DG + L HN II L
Sbjct: 354 KTRVTLTNHKKSVRAVVLHPRHYTFASGSPD-NIKQWKFPDGSFIQNLSGHNAIINTLTV 412
Query: 361 SPNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLF 182
+ + + A ++ +WD + + + + + S++ C A+ L
Sbjct: 413 NSDGVLVSGADNGTMHLWDWRTGYNFQRVHAAVQPGSLDSESGIFAC---AFDQSESRLL 469
Query: 181 AGYSDNTIRVWQ 146
+D TI+V++
Sbjct: 470 TAEADKTIKVYR 481
>AF044333-1|AAD09407.1| 514|Homo sapiens pleiotropic regulator 1
protein.
Length = 514
Score = 68.1 bits (159), Expect = 3e-11
Identities = 43/141 (30%), Positives = 69/141 (48%), Gaps = 2/141 (1%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
GS D+TIK+W+ LA K + GH V V S +P + SCG D+ VK W L
Sbjct: 222 GSADRTIKIWD-LASGKLKLSLTGHISTVRGVIVSTR--SPYLFSCGEDKQVKCWDLEYN 278
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-H-NDIITALC 365
K+ ++ GH + + + P + + +D A +WD+ +HTL H N + T C
Sbjct: 279 KVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRC 338
Query: 364 FSPNRYWLCAAFGPSIKIWDL 302
+ + + +I++WDL
Sbjct: 339 QAAEPQIITGSHDTTIRLWDL 359
Score = 63.7 bits (148), Expect = 6e-10
Identities = 49/171 (28%), Positives = 70/171 (40%), Gaps = 2/171 (1%)
Frame = -2
Query: 649 GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGS 470
GH WV C+ P N V+ DRT+K+W L + KLK++ GH + V VS
Sbjct: 202 GHLGWVRCIAVEPG--NQWFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRSP 259
Query: 469 LCASGGKDMKAMLWDLNDGKHL-HTLDHNDIITALCFSPNRYWLCAAFGPS-IKIWDLES 296
S G+D + WDL K + H H + L P L S +IWD+ +
Sbjct: 260 YLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVRT 319
Query: 295 KEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQV 143
K V L T+ +C + + G D TIR+W +
Sbjct: 320 KASVHTL------SGHTNAVATVRCQAAE-----PQIITGSHDTTIRLWDL 359
Score = 59.7 bits (138), Expect = 1e-08
Identities = 46/192 (23%), Positives = 83/192 (43%), Gaps = 2/192 (1%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECK-YTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
SRD T ++W+ + +T+ GH++ V+ VR A P I++ D T+++W L
Sbjct: 307 SRDSTARIWDVRTKASVHTLS--GHTNAVATVRCQA--AEPQIITGSHDTTIRLWDLVAG 362
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALCF 362
K ++ H + V + P ASG D W DG + L HN II L
Sbjct: 363 KTRVTLTNHKKSVRAVVLHPRHYTFASGSPD-NIKQWKFPDGSFIQNLSGHNAIINTLTV 421
Query: 361 SPNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLF 182
+ + + A ++ +WD + + + + + S++ C A+ L
Sbjct: 422 NSDGVLVSGADNGTMHLWDWRTGYNFQRVHAAVQPGSLDSESGIFAC---AFDQSESRLL 478
Query: 181 AGYSDNTIRVWQ 146
+D TI+V++
Sbjct: 479 TAEADKTIKVYR 490
>BC031227-1|AAH31227.2| 452|Homo sapiens WDR88 protein protein.
Length = 452
Score = 67.7 bits (158), Expect = 4e-11
Identities = 40/149 (26%), Positives = 75/149 (50%), Gaps = 10/149 (6%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQDDGHSDWVS--CVRFSPNHANPIIVSCGWDRTVKVWHL-- 548
S D+ IK+W+ ++ HS+ +S C FS + + + WD+ +K+W++
Sbjct: 275 SLDRCIKIWDVTSQATLLTITKAHSNAISNCCFTFSGH----FLCTSSWDKNLKIWNVHT 330
Query: 547 ---TNCKLKINHL-GHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDG-KHLHTLDHND 383
NC + + GH G +++ + D S SGG D +WD+ +G + L HND
Sbjct: 331 GEFRNCGACVTLMQGHEGSVSSCHFARDSSFLISGGFDRTVAIWDVAEGYRKLSLKGHND 390
Query: 382 IITALCFSPNRYW-LCAAFGPSIKIWDLE 299
+ + S N+ W L A+ ++++W++E
Sbjct: 391 WVMDVAISNNKKWILSASKDRTMRLWNIE 419
Score = 50.4 bits (115), Expect = 6e-06
Identities = 38/146 (26%), Positives = 67/146 (45%), Gaps = 4/146 (2%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
GS D T+KLW+ + ++D H V S + +++ +D+TV+ W L
Sbjct: 146 GSYDCTVKLWDPVDGS--VVRDFEHRPKAPVVECSITGDSSRVIAASYDKTVRAWDLETG 203
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASG-GKDMKAMLWDLNDGKHLHTL--DHNDIITAL 368
KL + + + ++ + SPDG SG D + D + + + H IT+
Sbjct: 204 KL-LWKVRYDTFIVSCKFSPDGKYVVSGFDVDHGICIMDAENITTVSVIKDHHTRSITSC 262
Query: 367 CFSPNRYWLCA-AFGPSIKIWDLESK 293
CF P+ + + + IKIWD+ S+
Sbjct: 263 CFDPDSQRVASVSLDRCIKIWDVTSQ 288
Score = 49.2 bits (112), Expect = 1e-05
Identities = 29/105 (27%), Positives = 50/105 (47%), Gaps = 5/105 (4%)
Frame = -2
Query: 715 SRDKTIKLWNT----LAECKYTIQ-DDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWH 551
S DK +K+WN C + GH VS F+ + + ++S G+DRTV +W
Sbjct: 318 SWDKNLKIWNVHTGEFRNCGACVTLMQGHEGSVSSCHFARDSS--FLISGGFDRTVAIWD 375
Query: 550 LTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLND 416
+ K++ GH+ ++ V +S + S KD LW++ +
Sbjct: 376 VAEGYRKLSLKGHNDWVMDVAISNNKKWILSASKDRTMRLWNIEE 420
Score = 45.6 bits (103), Expect = 2e-04
Identities = 43/197 (21%), Positives = 87/197 (44%), Gaps = 5/197 (2%)
Frame = -2
Query: 715 SRDKTIKLWNT-LAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
S DKT++ W+ + + ++ D VSC +FSP+ ++ D + + N
Sbjct: 190 SYDKTVRAWDLETGKLLWKVRYDTFI--VSC-KFSPD-GKYVVSGFDVDHGICIMDAENI 245
Query: 538 K-LKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD--HNDIITAL 368
+ + H+ + + PD AS D +WD+ L T+ H++ I+
Sbjct: 246 TTVSVIKDHHTRSITSCCFDPDSQRVASVSLDRCIKIWDVTSQATLLTITKAHSNAISNC 305
Query: 367 CFSPNRYWLC-AAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQ 191
CF+ + ++LC +++ ++KIW++ + E + Q + C ++ D
Sbjct: 306 CFTFSGHFLCTSSWDKNLKIWNVHTGEF--RNCGACVTLMQGHEGSVSSC---HFARDSS 360
Query: 190 TLFAGYSDNTIRVWQVS 140
L +G D T+ +W V+
Sbjct: 361 FLISGGFDRTVAIWDVA 377
Score = 39.1 bits (87), Expect = 0.016
Identities = 41/177 (23%), Positives = 70/177 (39%), Gaps = 4/177 (2%)
Frame = -2
Query: 649 GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTV--TVSPD 476
GH VS F + ++S +D TVK+W + + + H V +++ D
Sbjct: 126 GHEHAVSTCHFCVDDTK--LLSGSYDCTVKLWDPVDGSV-VRDFEHRPKAPVVECSITGD 182
Query: 475 GSLCASGGKDMKAMLWDLNDGKHLHTLDHNDIITALCFSPNRYWLCAAF--GPSIKIWDL 302
S + D WDL GK L + ++ I + FSP+ ++ + F I I D
Sbjct: 183 SSRVIAASYDKTVRAWDLETGKLLWKVRYDTFIVSCKFSPDGKYVVSGFDVDHGICIMDA 242
Query: 301 ESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQVSISA 131
E+ V ++ + DP D Q + + D I++W V+ A
Sbjct: 243 ENITTVSVIKDHHTRSITSCCFDP----------DSQRVASVSLDRCIKIWDVTSQA 289
>BC015887-1|AAH15887.1| 404|Homo sapiens WD repeat and SOCS
box-containing 2 protein.
Length = 404
Score = 67.7 bits (158), Expect = 4e-11
Identities = 48/198 (24%), Positives = 88/198 (44%), Gaps = 4/198 (2%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
G D IK+W + GH D V + F+P+ + I+VS D+T+++W L
Sbjct: 129 GLNDGQIKIWEVQTGL-LLLNLSGHQDVVRDLSFTPS-GSLILVSASRDKTLRIWDLNKH 186
Query: 538 KLKINHL-GHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALC 365
+I L GH ++ ++SPD S+ S + LW + + L+ H + +
Sbjct: 187 GKQIQVLSGHLQWVYCCSISPDCSMLCSAAGEKSVFLWSMRSYTLIRKLEGHQSSVVSCD 246
Query: 364 FSPNRYWL-CAAFGPSIKIWDLESKEMVEEL-RPEIINQTQTSKTDPPQCLSLAWSTDGQ 191
FSP+ L A++ ++ +WD + E + L ++ S S+ +S +G
Sbjct: 247 FSPDSALLVTASYDTNVIMWDPYTGERLRSLHHTQVDPAMDDSDVHISSLRSVCFSPEGL 306
Query: 190 TLFAGYSDNTIRVWQVSI 137
L D +R+W + +
Sbjct: 307 YLATVADDRLLRIWALEL 324
Score = 66.1 bits (154), Expect = 1e-10
Identities = 42/155 (27%), Positives = 71/155 (45%), Gaps = 14/155 (9%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK 536
SRDKT+++W+ K GH WV C SP+ + ++ S +++V +W + +
Sbjct: 173 SRDKTLRIWDLNKHGKQIQVLSGHLQWVYCCSISPDCS--MLCSAAGEKSVFLWSMRSYT 230
Query: 535 LKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDI-------- 380
L GH + + SPD +L + D ++WD G+ L +L H +
Sbjct: 231 LIRKLEGHQSSVVSCDFSPDSALLVTASYDTNVIMWDPYTGERLRSLHHTQVDPAMDDSD 290
Query: 379 -----ITALCFSPNRYWLC-AAFGPSIKIWDLESK 293
+ ++CFSP +L A ++IW LE K
Sbjct: 291 VHISSLRSVCFSPEGLYLATVADDRLLRIWALELK 325
>AF229181-1|AAF71302.1| 404|Homo sapiens CS box-containing WD
protein protein.
Length = 404
Score = 67.7 bits (158), Expect = 4e-11
Identities = 48/198 (24%), Positives = 88/198 (44%), Gaps = 4/198 (2%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
G D IK+W + GH D V + F+P+ + I+VS D+T+++W L
Sbjct: 129 GLNDGQIKIWEVQTGL-LLLNLSGHQDVVRDLSFTPS-GSLILVSASRDKTLRIWDLNKH 186
Query: 538 KLKINHL-GHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALC 365
+I L GH ++ ++SPD S+ S + LW + + L+ H + +
Sbjct: 187 GKQIQVLSGHLQWVYCCSISPDCSMLCSAAGEKSVFLWSMRSYTLIRKLEGHQSSVVSCD 246
Query: 364 FSPNRYWL-CAAFGPSIKIWDLESKEMVEEL-RPEIINQTQTSKTDPPQCLSLAWSTDGQ 191
FSP+ L A++ ++ +WD + E + L ++ S S+ +S +G
Sbjct: 247 FSPDSALLVTASYDTNVIMWDPYTGERLRSLHHTQVDPAMDDSDVHISSLRSVCFSPEGL 306
Query: 190 TLFAGYSDNTIRVWQVSI 137
L D +R+W + +
Sbjct: 307 YLATVADDRLLRIWALEL 324
Score = 66.1 bits (154), Expect = 1e-10
Identities = 42/155 (27%), Positives = 71/155 (45%), Gaps = 14/155 (9%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK 536
SRDKT+++W+ K GH WV C SP+ + ++ S +++V +W + +
Sbjct: 173 SRDKTLRIWDLNKHGKQIQVLSGHLQWVYCCSISPDCS--MLCSAAGEKSVFLWSMRSYT 230
Query: 535 LKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDI-------- 380
L GH + + SPD +L + D ++WD G+ L +L H +
Sbjct: 231 LIRKLEGHQSSVVSCDFSPDSALLVTASYDTNVIMWDPYTGERLRSLHHTQVDPAMDDSD 290
Query: 379 -----ITALCFSPNRYWLC-AAFGPSIKIWDLESK 293
+ ++CFSP +L A ++IW LE K
Sbjct: 291 VHISSLRSVCFSPEGLYLATVADDRLLRIWALELK 325
>AF163324-1|AAF80478.1| 404|Homo sapiens WSB-2 protein.
Length = 404
Score = 67.7 bits (158), Expect = 4e-11
Identities = 48/198 (24%), Positives = 88/198 (44%), Gaps = 4/198 (2%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
G D IK+W + GH D V + F+P+ + I+VS D+T+++W L
Sbjct: 129 GLNDGQIKIWEVQTGL-LLLNLSGHQDVVRDLSFTPS-GSLILVSASRDKTLRIWDLNKH 186
Query: 538 KLKINHL-GHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALC 365
+I L GH ++ ++SPD S+ S + LW + + L+ H + +
Sbjct: 187 GKQIQVLSGHLQWVYCCSISPDCSMLCSAAGEKSVFLWSMRSYTLIRKLEGHQSSVVSCD 246
Query: 364 FSPNRYWL-CAAFGPSIKIWDLESKEMVEEL-RPEIINQTQTSKTDPPQCLSLAWSTDGQ 191
FSP+ L A++ ++ +WD + E + L ++ S S+ +S +G
Sbjct: 247 FSPDSALLVTASYDTNVIMWDPYTGERLRSLHHTQVDPAMDDSDVHISSLRSVCFSPEGL 306
Query: 190 TLFAGYSDNTIRVWQVSI 137
L D +R+W + +
Sbjct: 307 YLATVADDRLLRIWALEL 324
Score = 66.1 bits (154), Expect = 1e-10
Identities = 42/155 (27%), Positives = 71/155 (45%), Gaps = 14/155 (9%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK 536
SRDKT+++W+ K GH WV C SP+ + ++ S +++V +W + +
Sbjct: 173 SRDKTLRIWDLNKHGKQIQVLSGHLQWVYCCSISPDCS--MLCSAAGEKSVFLWSMRSYT 230
Query: 535 LKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDI-------- 380
L GH + + SPD +L + D ++WD G+ L +L H +
Sbjct: 231 LIRKLEGHQSSVVSCDFSPDSALLVTASYDTNVIMWDPYTGERLRSLHHTQVDPAMDDSD 290
Query: 379 -----ITALCFSPNRYWLC-AAFGPSIKIWDLESK 293
+ ++CFSP +L A ++IW LE K
Sbjct: 291 VHISSLRSVCFSPEGLYLATVADDRLLRIWALELK 325
>AL031282-15|CAI20051.1| 197|Homo sapiens guanine nucleotide
binding protein (G protein), beta polypeptide 1 protein.
Length = 197
Score = 67.3 bits (157), Expect = 5e-11
Identities = 48/167 (28%), Positives = 78/167 (46%), Gaps = 4/167 (2%)
Frame = -2
Query: 637 WVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCAS 458
++SC RF + N I+ S G D T +W + + GH+G + +++++PD L S
Sbjct: 2 YLSCCRFLDD--NQIVTSSG-DTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVS 58
Query: 457 GGKDMKAMLWDLNDGKHLHTL-DHNDIITALCFSPN-RYWLCAAFGPSIKIWDLESKEMV 284
G D A LWD+ +G T H I A+CF PN + + + +++DL + +
Sbjct: 59 GACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQ-- 116
Query: 283 EELRPEIINQTQTSKTDPPQC--LSLAWSTDGQTLFAGYSDNTIRVW 149
+ T D C S+++S G+ L AGY D VW
Sbjct: 117 ---------ELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVW 154
Score = 55.6 bits (128), Expect = 2e-07
Identities = 38/141 (26%), Positives = 65/141 (46%), Gaps = 4/141 (2%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK 536
S D T LW+ + + T GH+ V + +P+ + VS D + K+W +
Sbjct: 18 SGDTTCALWD-IETGQQTTTFTGHTGDVMSLSLAPD--TRLFVSGACDASAKLWDVREGM 74
Query: 535 LKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDI---ITALC 365
+ GH +N + P+G+ A+G D L+DL + L T H++I IT++
Sbjct: 75 CRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVS 134
Query: 364 FSPNRYWLCAAFGP-SIKIWD 305
FS + L A + + +WD
Sbjct: 135 FSKSGRLLLAGYDDFNCNVWD 155
>EF011621-1|ABK41111.1| 357|Homo sapiens CDW11/WDR57 protein.
Length = 357
Score = 66.1 bits (154), Expect = 1e-10
Identities = 48/191 (25%), Positives = 79/191 (41%), Gaps = 2/191 (1%)
Frame = -2
Query: 709 DKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLK 530
D+ I LWN +C GHS V + + N ++ S D+TV VW +
Sbjct: 87 DRLILLWNVYGDCDNYATLKGHSGAVMELHY--NTDGSMLFSASTDKTVAVWDSETGERV 144
Query: 529 INHLGHSGYLNTVTVSPDG-SLCASGGKDMKAMLWDLNDGKHLHTLDHNDIITALCFSPN 353
GH+ ++N+ + G L +G D LWD+ + T + + A+ F+
Sbjct: 145 KRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDIRKKAAIQTFQNTYQVLAVTFNDT 204
Query: 352 RYWLCAA-FGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAG 176
+ + IK+WDL ++ T T + L+ S++G L +
Sbjct: 205 SDQIISGGIDNDIKVWDLRQNKL-----------TYTMRGHADSVTGLSLSSEGSYLLSN 253
Query: 175 YSDNTIRVWQV 143
DNT+RVW V
Sbjct: 254 AMDNTVRVWDV 264
Score = 65.3 bits (152), Expect = 2e-10
Identities = 55/196 (28%), Positives = 87/196 (44%), Gaps = 4/196 (2%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQDDGHSDWV-SCVRFSPNHANPIIVSCGWDR-TVKVWHLTN 542
S DKT+ +W++ + + GH+ +V SC P P +V G D TVK+W +
Sbjct: 128 STDKTVAVWDSETGERVK-RLKGHTSFVNSCY---PARRGPQLVCTGSDDGTVKLWDIRK 183
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALC 365
K I ++ + VT + SGG D +WDL K +T+ H D +T L
Sbjct: 184 -KAAIQTFQNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVTGLS 242
Query: 364 FSPN-RYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQT 188
S Y L A ++++WD+ + + R I Q + L +WS DG
Sbjct: 243 LSSEGSYLLSNAMDNTVRVWDV--RPFAPKERCVKIFQGNVHNFEK-NLLRCSWSPDGSK 299
Query: 187 LFAGYSDNTIRVWQVS 140
+ AG +D + VW +
Sbjct: 300 IAAGSADRFVYVWDTT 315
Score = 62.9 bits (146), Expect = 1e-09
Identities = 41/173 (23%), Positives = 76/173 (43%), Gaps = 4/173 (2%)
Frame = -2
Query: 649 GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT-NCKLKINHLGHSGYLNTVTVSPDG 473
GH V C +F PN + + S G+DR + +W++ +C GHSG + + + DG
Sbjct: 64 GHEGEVYCCKFHPNGST--LASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTDG 121
Query: 472 SLCASGGKDMKAMLWDLNDGKHLHTLDHNDIITALCFSPNR--YWLCAAFGP-SIKIWDL 302
S+ S D +WD G+ + L + C+ R +C ++K+WD+
Sbjct: 122 SMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDI 181
Query: 301 ESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQV 143
K ++ + + Q L++ ++ + +G DN I+VW +
Sbjct: 182 RKKAAIQTFQ------------NTYQVLAVTFNDTSDQIISGGIDNDIKVWDL 222
Score = 51.6 bits (118), Expect = 3e-06
Identities = 33/99 (33%), Positives = 48/99 (48%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
GS D T+KLW+ K IQ ++ V V F N + I+S G D +KVW L
Sbjct: 170 GSDDGTVKLWDIRK--KAAIQTFQNTYQVLAVTF--NDTSDQIISGGIDNDIKVWDLRQN 225
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDL 422
KL GH+ + +++S +GS S D +WD+
Sbjct: 226 KLTYTMRGHADSVTGLSLSSEGSYLLSNAMDNTVRVWDV 264
Score = 43.2 bits (97), Expect = 0.001
Identities = 38/131 (29%), Positives = 57/131 (43%), Gaps = 9/131 (6%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT-- 545
G D IK+W+ L + K T GH+D V+ + S + ++S D TV+VW +
Sbjct: 211 GGIDNDIKVWD-LRQNKLTYTMRGHADSVTGLSLSSEGS--YLLSNAMDNTVRVWDVRPF 267
Query: 544 ----NCKLKINHLGHSGYLNTVTVS--PDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHN 386
C H+ N + S PDGS A+G D +WD + L+ L H
Sbjct: 268 APKERCVKIFQGNVHNFEKNLLRCSWSPDGSKIAAGSADRFVYVWDTTSRRILYKLPGHA 327
Query: 385 DIITALCFSPN 353
I + F P+
Sbjct: 328 GSINEVAFHPD 338
Score = 37.5 bits (83), Expect = 0.048
Identities = 24/101 (23%), Positives = 44/101 (43%), Gaps = 5/101 (4%)
Frame = -2
Query: 709 DKTIKLWNTLA-----ECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 545
D T+++W+ C Q + H+ + +R S + I + DR V VW T
Sbjct: 256 DNTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRCSWSPDGSKIAAGSADRFVYVWDTT 315
Query: 544 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDL 422
+ ++ GH+G +N V PD + S D + + ++
Sbjct: 316 SRRILYKLPGHAGSINEVAFHPDEPIIISASSDKRLYMGEI 356
Score = 29.9 bits (64), Expect = 9.6
Identities = 14/42 (33%), Positives = 21/42 (50%)
Frame = -2
Query: 220 LSLAWSTDGQTLFAGYSDNTIRVWQVSISAR*A*LSTLISFI 95
+ L ++TDG LF+ +D T+ VW R L SF+
Sbjct: 113 MELHYNTDGSMLFSASTDKTVAVWDSETGERVKRLKGHTSFV 154
>BC021110-1|AAH21110.1| 421|Homo sapiens WD repeat and SOCS
box-containing 1 protein.
Length = 421
Score = 66.1 bits (154), Expect = 1e-10
Identities = 51/193 (26%), Positives = 84/193 (43%), Gaps = 4/193 (2%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK 536
SRDKT+++W+ + GH +WV FSP+ + ++ S G + V +W++
Sbjct: 190 SRDKTLRVWDLKDDGNMMKVLRGHQNWVYSCAFSPDSS--MLCSVGASKAVFLWNMDKYT 247
Query: 535 LKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDIITALCFS- 359
+ GH + SPDG+L A+ D + +WD ++G L H F+
Sbjct: 248 MIRKLEGHHHDVVACDFSPDGALLATASYDTRVYIWDPHNGDILMEFGHLFPPPTPIFAG 307
Query: 358 -PNRYWL-CAAFG-PSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQT 188
N W+ +F + + L +MV R + Q + C A+STDG
Sbjct: 308 GANDRWVRSVSFSHDGLHVASLADDKMVRFWRIDEDYPVQVAPLSNGLC--CAFSTDGSV 365
Query: 187 LFAGYSDNTIRVW 149
L AG D ++ W
Sbjct: 366 LAAGTHDGSVYFW 378
Score = 61.7 bits (143), Expect = 3e-09
Identities = 48/197 (24%), Positives = 92/197 (46%), Gaps = 5/197 (2%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
G + IK+W+ K + H++ V + F+P+ + I+VS D+T++VW L +
Sbjct: 146 GLNNGRIKIWDVYTG-KLLLNLVDHTEVVRDLTFAPD-GSLILVSASRDKTLRVWDLKDD 203
Query: 538 KLKINHL-GHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALC 365
+ L GH ++ + SPD S+ S G LW+++ + L+ H+ + A
Sbjct: 204 GNMMKVLRGHQNWVYSCAFSPDSSMLCSVGASKAVFLWNMDKYTMIRKLEGHHHDVVACD 263
Query: 364 FSPNRYWLC-AAFGPSIKIWDLESKEMVEELRPEIINQTQ--TSKTDPPQCLSLAWSTDG 194
FSP+ L A++ + IWD + +++ E T + S+++S DG
Sbjct: 264 FSPDGALLATASYDTRVYIWDPHNGDILMEFGHLFPPPTPIFAGGANDRWVRSVSFSHDG 323
Query: 193 QTLFAGYSDNTIRVWQV 143
+ + D +R W++
Sbjct: 324 LHVASLADDKMVRFWRI 340
>BC015920-1|AAH15920.1| 297|Homo sapiens GNB3 protein protein.
Length = 297
Score = 66.1 bits (154), Expect = 1e-10
Identities = 50/169 (29%), Positives = 79/169 (46%), Gaps = 3/169 (1%)
Frame = -2
Query: 646 HSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSL 467
H+ ++SC RF + N I+ S G D T +W + + K +GH+G ++ VSPD +L
Sbjct: 142 HTGYLSCCRFLDD--NNIVTSSG-DTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDFNL 198
Query: 466 CASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALC-FSPNRYWLCAAFGP-SIKIWDLES 296
SG D A LWD+ +G T H I A+C FS + L A + + +WD
Sbjct: 199 FISGACDASAKLWDVREGTCRQTFTGHESDINAICFFSLSGRLLFAGYDDFNCNVWDSMK 258
Query: 295 KEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVW 149
E V L + + CL + + DG + G D+ +++W
Sbjct: 259 SERVGIL---------SGHDNRVSCLGV--TADGMAVATGSWDSFLKIW 296
Score = 52.4 bits (120), Expect = 2e-06
Identities = 49/179 (27%), Positives = 73/179 (40%), Gaps = 7/179 (3%)
Frame = -2
Query: 643 SDWVSCVRFSPNHANPIIVSCGW-DRTVKVWHLT----NCKLKINHLGHSGYLNTVTVSP 479
S WV ++P+ N V+CG D +++L N K+ H+GYL+
Sbjct: 97 SSWVMTCAYAPS-GN--FVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLD 153
Query: 478 DGSLCASGGKDMKAMLWDLNDGKHLHT-LDHNDIITALCFSPN-RYWLCAAFGPSIKIWD 305
D ++ S G D LWD+ G+ + H +L SP+ ++ A S K+WD
Sbjct: 154 DNNIVTSSG-DTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWD 212
Query: 304 LESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQVSISAR 128
+ R QT T + +S G+ LFAGY D VW S R
Sbjct: 213 V---------REGTCRQTFTGHESDINAICF-FSLSGRLLFAGYDDFNCNVWDSMKSER 261
>BC001494-1|AAH01494.1| 357|Homo sapiens WD repeat domain 57 (U5
snRNP specific) protein.
Length = 357
Score = 66.1 bits (154), Expect = 1e-10
Identities = 48/191 (25%), Positives = 79/191 (41%), Gaps = 2/191 (1%)
Frame = -2
Query: 709 DKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLK 530
D+ I LWN +C GHS V + + N ++ S D+TV VW +
Sbjct: 87 DRLILLWNVYGDCDNYATLKGHSGAVMELHY--NTDGSMLFSASTDKTVAVWDSETGERV 144
Query: 529 INHLGHSGYLNTVTVSPDG-SLCASGGKDMKAMLWDLNDGKHLHTLDHNDIITALCFSPN 353
GH+ ++N+ + G L +G D LWD+ + T + + A+ F+
Sbjct: 145 KRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDIRKKAAIQTFQNTYQVLAVTFNDT 204
Query: 352 RYWLCAA-FGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAG 176
+ + IK+WDL ++ T T + L+ S++G L +
Sbjct: 205 SDQIISGGIDNDIKVWDLRQNKL-----------TYTMRGHADSVTGLSLSSEGSYLLSN 253
Query: 175 YSDNTIRVWQV 143
DNT+RVW V
Sbjct: 254 AMDNTVRVWDV 264
Score = 65.3 bits (152), Expect = 2e-10
Identities = 55/196 (28%), Positives = 87/196 (44%), Gaps = 4/196 (2%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQDDGHSDWV-SCVRFSPNHANPIIVSCGWDR-TVKVWHLTN 542
S DKT+ +W++ + + GH+ +V SC P P +V G D TVK+W +
Sbjct: 128 STDKTVAVWDSETGERVK-RLKGHTSFVNSCY---PARRGPQLVCTGSDDGTVKLWDIRK 183
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALC 365
K I ++ + VT + SGG D +WDL K +T+ H D +T L
Sbjct: 184 -KAAIQTFQNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVTGLS 242
Query: 364 FSPN-RYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQT 188
S Y L A ++++WD+ + + R I Q + L +WS DG
Sbjct: 243 LSSEGSYLLSNAMDNTVRVWDV--RPFAPKERCVKIFQGNVHNFEK-NLLRCSWSPDGSK 299
Query: 187 LFAGYSDNTIRVWQVS 140
+ AG +D + VW +
Sbjct: 300 IAAGSADRFVYVWDTT 315
Score = 62.9 bits (146), Expect = 1e-09
Identities = 41/173 (23%), Positives = 76/173 (43%), Gaps = 4/173 (2%)
Frame = -2
Query: 649 GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT-NCKLKINHLGHSGYLNTVTVSPDG 473
GH V C +F PN + + S G+DR + +W++ +C GHSG + + + DG
Sbjct: 64 GHEGEVYCCKFHPNGST--LASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTDG 121
Query: 472 SLCASGGKDMKAMLWDLNDGKHLHTLDHNDIITALCFSPNR--YWLCAAFGP-SIKIWDL 302
S+ S D +WD G+ + L + C+ R +C ++K+WD+
Sbjct: 122 SMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDI 181
Query: 301 ESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQV 143
K ++ + + Q L++ ++ + +G DN I+VW +
Sbjct: 182 RKKAAIQTFQ------------NTYQVLAVTFNDTSDQIISGGIDNDIKVWDL 222
Score = 51.6 bits (118), Expect = 3e-06
Identities = 33/99 (33%), Positives = 48/99 (48%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
GS D T+KLW+ K IQ ++ V V F N + I+S G D +KVW L
Sbjct: 170 GSDDGTVKLWDIRK--KAAIQTFQNTYQVLAVTF--NDTSDQIISGGIDNDIKVWDLRQN 225
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDL 422
KL GH+ + +++S +GS S D +WD+
Sbjct: 226 KLTYTMRGHADSVTGLSLSSEGSYLLSNAMDNTVRVWDV 264
Score = 43.2 bits (97), Expect = 0.001
Identities = 38/131 (29%), Positives = 57/131 (43%), Gaps = 9/131 (6%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT-- 545
G D IK+W+ L + K T GH+D V+ + S + ++S D TV+VW +
Sbjct: 211 GGIDNDIKVWD-LRQNKLTYTMRGHADSVTGLSLSSEGS--YLLSNAMDNTVRVWDVRPF 267
Query: 544 ----NCKLKINHLGHSGYLNTVTVS--PDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHN 386
C H+ N + S PDGS A+G D +WD + L+ L H
Sbjct: 268 APKERCVKIFQGNVHNFEKNLLRCSWSPDGSKIAAGSADRFVYVWDTTSRRILYKLPGHA 327
Query: 385 DIITALCFSPN 353
I + F P+
Sbjct: 328 GSINEVAFHPD 338
Score = 37.5 bits (83), Expect = 0.048
Identities = 24/101 (23%), Positives = 44/101 (43%), Gaps = 5/101 (4%)
Frame = -2
Query: 709 DKTIKLWNTLA-----ECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 545
D T+++W+ C Q + H+ + +R S + I + DR V VW T
Sbjct: 256 DNTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRCSWSPDGSKIAAGSADRFVYVWDTT 315
Query: 544 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDL 422
+ ++ GH+G +N V PD + S D + + ++
Sbjct: 316 SRRILYKLPGHAGSINEVAFHPDEPIIISASSDKRLYMGEI 356
Score = 29.9 bits (64), Expect = 9.6
Identities = 14/42 (33%), Positives = 21/42 (50%)
Frame = -2
Query: 220 LSLAWSTDGQTLFAGYSDNTIRVWQVSISAR*A*LSTLISFI 95
+ L ++TDG LF+ +D T+ VW R L SF+
Sbjct: 113 MELHYNTDGSMLFSASTDKTVAVWDSETGERVKRLKGHTSFV 154
>AL451070-1|CAH71848.1| 357|Homo sapiens WD repeat domain 57 (U5
snRNP specific) protein.
Length = 357
Score = 66.1 bits (154), Expect = 1e-10
Identities = 48/191 (25%), Positives = 79/191 (41%), Gaps = 2/191 (1%)
Frame = -2
Query: 709 DKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLK 530
D+ I LWN +C GHS V + + N ++ S D+TV VW +
Sbjct: 87 DRLILLWNVYGDCDNYATLKGHSGAVMELHY--NTDGSMLFSASTDKTVAVWDSETGERV 144
Query: 529 INHLGHSGYLNTVTVSPDG-SLCASGGKDMKAMLWDLNDGKHLHTLDHNDIITALCFSPN 353
GH+ ++N+ + G L +G D LWD+ + T + + A+ F+
Sbjct: 145 KRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDIRKKAAIQTFQNTYQVLAVTFNDT 204
Query: 352 RYWLCAA-FGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAG 176
+ + IK+WDL ++ T T + L+ S++G L +
Sbjct: 205 SDQIISGGIDNDIKVWDLRQNKL-----------TYTMRGHADSVTGLSLSSEGSYLLSN 253
Query: 175 YSDNTIRVWQV 143
DNT+RVW V
Sbjct: 254 AMDNTVRVWDV 264
Score = 65.3 bits (152), Expect = 2e-10
Identities = 55/196 (28%), Positives = 87/196 (44%), Gaps = 4/196 (2%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQDDGHSDWV-SCVRFSPNHANPIIVSCGWDR-TVKVWHLTN 542
S DKT+ +W++ + + GH+ +V SC P P +V G D TVK+W +
Sbjct: 128 STDKTVAVWDSETGERVK-RLKGHTSFVNSCY---PARRGPQLVCTGSDDGTVKLWDIRK 183
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALC 365
K I ++ + VT + SGG D +WDL K +T+ H D +T L
Sbjct: 184 -KAAIQTFQNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVTGLS 242
Query: 364 FSPN-RYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQT 188
S Y L A ++++WD+ + + R I Q + L +WS DG
Sbjct: 243 LSSEGSYLLSNAMDNTVRVWDV--RPFAPKERCVKIFQGNVHNFEK-NLLRCSWSPDGSK 299
Query: 187 LFAGYSDNTIRVWQVS 140
+ AG +D + VW +
Sbjct: 300 IAAGSADRFVYVWDTT 315
Score = 62.9 bits (146), Expect = 1e-09
Identities = 41/173 (23%), Positives = 76/173 (43%), Gaps = 4/173 (2%)
Frame = -2
Query: 649 GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT-NCKLKINHLGHSGYLNTVTVSPDG 473
GH V C +F PN + + S G+DR + +W++ +C GHSG + + + DG
Sbjct: 64 GHEGEVYCCKFHPNGST--LASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTDG 121
Query: 472 SLCASGGKDMKAMLWDLNDGKHLHTLDHNDIITALCFSPNR--YWLCAAFGP-SIKIWDL 302
S+ S D +WD G+ + L + C+ R +C ++K+WD+
Sbjct: 122 SMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDI 181
Query: 301 ESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQV 143
K ++ + + Q L++ ++ + +G DN I+VW +
Sbjct: 182 RKKAAIQTFQ------------NTYQVLAVTFNDTSDQIISGGIDNDIKVWDL 222
Score = 51.6 bits (118), Expect = 3e-06
Identities = 33/99 (33%), Positives = 48/99 (48%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
GS D T+KLW+ K IQ ++ V V F N + I+S G D +KVW L
Sbjct: 170 GSDDGTVKLWDIRK--KAAIQTFQNTYQVLAVTF--NDTSDQIISGGIDNDIKVWDLRQN 225
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDL 422
KL GH+ + +++S +GS S D +WD+
Sbjct: 226 KLTYTMRGHADSVTGLSLSSEGSYLLSNAMDNTVRVWDV 264
Score = 43.2 bits (97), Expect = 0.001
Identities = 38/131 (29%), Positives = 57/131 (43%), Gaps = 9/131 (6%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT-- 545
G D IK+W+ L + K T GH+D V+ + S + ++S D TV+VW +
Sbjct: 211 GGIDNDIKVWD-LRQNKLTYTMRGHADSVTGLSLSSEGS--YLLSNAMDNTVRVWDVRPF 267
Query: 544 ----NCKLKINHLGHSGYLNTVTVS--PDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHN 386
C H+ N + S PDGS A+G D +WD + L+ L H
Sbjct: 268 APKERCVKIFQGNVHNFEKNLLRCSWSPDGSKIAAGSADRFVYVWDTTSRRILYKLPGHA 327
Query: 385 DIITALCFSPN 353
I + F P+
Sbjct: 328 GSINEVAFHPD 338
Score = 37.5 bits (83), Expect = 0.048
Identities = 24/101 (23%), Positives = 44/101 (43%), Gaps = 5/101 (4%)
Frame = -2
Query: 709 DKTIKLWNTLA-----ECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 545
D T+++W+ C Q + H+ + +R S + I + DR V VW T
Sbjct: 256 DNTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRCSWSPDGSKIAAGSADRFVYVWDTT 315
Query: 544 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDL 422
+ ++ GH+G +N V PD + S D + + ++
Sbjct: 316 SRRILYKLPGHAGSINEVAFHPDEPIIISASSDKRLYMGEI 356
Score = 29.9 bits (64), Expect = 9.6
Identities = 14/42 (33%), Positives = 21/42 (50%)
Frame = -2
Query: 220 LSLAWSTDGQTLFAGYSDNTIRVWQVSISAR*A*LSTLISFI 95
+ L ++TDG LF+ +D T+ VW R L SF+
Sbjct: 113 MELHYNTDGSMLFSASTDKTVAVWDSETGERVKRLKGHTSFV 154
>AK074917-1|BAC11291.1| 421|Homo sapiens protein ( Homo sapiens
cDNA FLJ90436 fis, clone NT2RP3000820, weakly similar to
PUTATIVE SERINE/THREONINE-PROTEIN KINASE PKWA (EC
2.7.1.-). ).
Length = 421
Score = 66.1 bits (154), Expect = 1e-10
Identities = 51/193 (26%), Positives = 84/193 (43%), Gaps = 4/193 (2%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK 536
SRDKT+++W+ + GH +WV FSP+ + ++ S G + V +W++
Sbjct: 190 SRDKTLRVWDLKDDGNMMKVLRGHQNWVYSCAFSPDSS--MLCSVGASKAVFLWNMDKYT 247
Query: 535 LKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDIITALCFS- 359
+ GH + SPDG+L A+ D + +WD ++G L H F+
Sbjct: 248 MIRKLEGHHHDVVACDFSPDGALLATASYDTRVYIWDPHNGDILMEFGHLFPPPTPIFAG 307
Query: 358 -PNRYWL-CAAFG-PSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQT 188
N W+ +F + + L +MV R + Q + C A+STDG
Sbjct: 308 GANDRWVRSVSFSHDGLHVASLADDKMVRFWRIDEDYPVQVAPLSNGLC--CAFSTDGSV 365
Query: 187 LFAGYSDNTIRVW 149
L AG D ++ W
Sbjct: 366 LAAGTHDGSVYFW 378
Score = 61.7 bits (143), Expect = 3e-09
Identities = 48/197 (24%), Positives = 92/197 (46%), Gaps = 5/197 (2%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
G + IK+W+ K + H++ V + F+P+ + I+VS D+T++VW L +
Sbjct: 146 GLNNGRIKIWDVYTG-KLLLNLVDHTEVVRDLTFAPD-GSLILVSASRDKTLRVWDLKDD 203
Query: 538 KLKINHL-GHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALC 365
+ L GH ++ + SPD S+ S G LW+++ + L+ H+ + A
Sbjct: 204 GNMMKVLRGHQNWVYSCAFSPDSSMLCSVGASKAVFLWNMDKYTMIRKLEGHHHDVVACD 263
Query: 364 FSPNRYWLC-AAFGPSIKIWDLESKEMVEELRPEIINQTQ--TSKTDPPQCLSLAWSTDG 194
FSP+ L A++ + IWD + +++ E T + S+++S DG
Sbjct: 264 FSPDGALLATASYDTRVYIWDPHNGDILMEFGHLFPPPTPIFAGGANDRWVRSVSFSHDG 323
Query: 193 QTLFAGYSDNTIRVWQV 143
+ + D +R W++
Sbjct: 324 LHVASLADDKMVRFWRI 340
>AF240696-1|AAF82746.1| 275|Homo sapiens WSB1 isoform 2 protein.
Length = 275
Score = 66.1 bits (154), Expect = 1e-10
Identities = 51/193 (26%), Positives = 84/193 (43%), Gaps = 4/193 (2%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK 536
SRDKT+++W+ + GH +WV FSP+ + ++ S G + V +W++
Sbjct: 44 SRDKTLRVWDLKDDGNMMKVLRGHQNWVYSCAFSPDSS--MLCSVGASKAVFLWNMDKYT 101
Query: 535 LKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDIITALCFS- 359
+ GH + SPDG+L A+ D + +WD ++G L H F+
Sbjct: 102 MIRKLEGHHHDVVACDFSPDGALLATASYDTRVYIWDPHNGDILMEFGHLFPPPTPIFAG 161
Query: 358 -PNRYWL-CAAFG-PSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQT 188
N W+ +F + + L +MV R + Q + C A+STDG
Sbjct: 162 GANDRWVRSVSFSHDGLHVASLADDKMVRFWRIDEDYPVQVAPLSNGLC--CAFSTDGSV 219
Query: 187 LFAGYSDNTIRVW 149
L AG D ++ W
Sbjct: 220 LAAGTHDGSVYFW 232
Score = 58.4 bits (135), Expect = 2e-08
Identities = 43/173 (24%), Positives = 83/173 (47%), Gaps = 5/173 (2%)
Frame = -2
Query: 646 HSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHL-GHSGYLNTVTVSPDGS 470
H++ V + F+P+ + I+VS D+T++VW L + + L GH ++ + SPD S
Sbjct: 23 HTEVVRDLTFAPD-GSLILVSASRDKTLRVWDLKDDGNMMKVLRGHQNWVYSCAFSPDSS 81
Query: 469 LCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALCFSPNRYWLC-AAFGPSIKIWDLES 296
+ S G LW+++ + L+ H+ + A FSP+ L A++ + IWD +
Sbjct: 82 MLCSVGASKAVFLWNMDKYTMIRKLEGHHHDVVACDFSPDGALLATASYDTRVYIWDPHN 141
Query: 295 KEMVEELRPEIINQTQ--TSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQV 143
+++ E T + S+++S DG + + D +R W++
Sbjct: 142 GDILMEFGHLFPPPTPIFAGGANDRWVRSVSFSHDGLHVASLADDKMVRFWRI 194
Score = 49.2 bits (112), Expect = 1e-05
Identities = 27/92 (29%), Positives = 50/92 (54%), Gaps = 4/92 (4%)
Frame = -2
Query: 538 KLKINHLGHSGYLNTVTVSPDGSL-CASGGKDMKAMLWDL-NDGKHLHTL-DHNDIITAL 368
KL +N + H+ + +T +PDGSL S +D +WDL +DG + L H + + +
Sbjct: 15 KLLLNLVDHTEVVRDLTFAPDGSLILVSASRDKTLRVWDLKDDGNMMKVLRGHQNWVYSC 74
Query: 367 CFSPNRYWLCA-AFGPSIKIWDLESKEMVEEL 275
FSP+ LC+ ++ +W+++ M+ +L
Sbjct: 75 AFSPDSSMLCSVGASKAVFLWNMDKYTMIRKL 106
>AF208838-1|AAL34973.1| 410|Homo sapiens Miller-Dieker
lissencephaly protein protein.
Length = 410
Score = 66.1 bits (154), Expect = 1e-10
Identities = 47/170 (27%), Positives = 80/170 (47%), Gaps = 23/170 (13%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQD-DGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
SRDKTIK+W + Y ++ GH +WV VR PN +I SC D+TV+VW +
Sbjct: 211 SRDKTIKMWEV--QTGYCVKTFTGHREWVRMVR--PNQDGTLIASCSNDQTVRVWVVATK 266
Query: 538 KLKINHLGHSGYLNTVTVSPD--------------------GSLCASGGKDMKAMLWDLN 419
+ K H + ++ +P+ G SG +D +WD++
Sbjct: 267 ECKAELREHEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVS 326
Query: 418 DGKHLHTL-DHNDIITALCF-SPNRYWLCAAFGPSIKIWDLESKEMVEEL 275
G L TL H++ + + F S ++ L A ++++WD ++K ++ L
Sbjct: 327 TGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTL 376
Score = 53.2 bits (122), Expect = 9e-07
Identities = 29/99 (29%), Positives = 47/99 (47%), Gaps = 1/99 (1%)
Frame = -2
Query: 718 GSRDKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
GSRDKTIK+W+ + C T+ GH +WV V F + I+SC D+T++VW N
Sbjct: 314 GSRDKTIKMWDVSTGMCLMTLV--GHDNWVRGVLF--HSGGKFILSCADDKTLRVWDYKN 369
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWD 425
+ H ++ ++ +G D +W+
Sbjct: 370 KRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWE 408
Score = 50.0 bits (114), Expect = 8e-06
Identities = 34/158 (21%), Positives = 69/158 (43%), Gaps = 21/158 (13%)
Frame = -2
Query: 715 SRDKTIKLWNTLA-ECKYTIQDDGHSDWVSCVRFSPNHA------------------NPI 593
S D+T+++W ECK +++ H V C+ ++P + P
Sbjct: 253 SNDQTVRVWVVATKECKAELRE--HEHVVECISWAPESSYSSISEATGSETKKSGKPGPF 310
Query: 592 IVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDG 413
++S D+T+K+W ++ + +GH ++ V G S D +WD +
Sbjct: 311 LLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNK 370
Query: 412 KHLHTLD-HNDIITALCFSPNR-YWLCAAFGPSIKIWD 305
+ + TL+ H +T+L F Y + + ++K+W+
Sbjct: 371 RCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWE 408
Score = 48.8 bits (111), Expect = 2e-05
Identities = 44/179 (24%), Positives = 80/179 (44%), Gaps = 2/179 (1%)
Frame = -2
Query: 670 KYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTV 491
KY + GH V+ V F P + ++VS D T+KVW + GH+ + +
Sbjct: 101 KYALS--GHRSPVTRVIFHPVFS--VMVSASEDATIKVWDYETGDFERTLKGHTDSVQDI 156
Query: 490 TVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCFSPN-RYWLCAAFGPSI 317
+ G L AS DM L D + + T+ H+ ++++ PN + + A+ +I
Sbjct: 157 SFDHSGKLLASCSADMTIKLRDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTI 216
Query: 316 KIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQVS 140
K+W++++ V+ ++ P Q DG + + +D T+RVW V+
Sbjct: 217 KMWEVQTGYCVKTFTG---HREWVRMVRPNQ--------DGTLIASCSNDQTVRVWVVA 264
Score = 48.0 bits (109), Expect = 3e-05
Identities = 36/122 (29%), Positives = 56/122 (45%), Gaps = 2/122 (1%)
Frame = -2
Query: 715 SRDKTIKLWNTLA-ECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
S D TIKL + EC T+ GH VS V PN + IVS D+T+K+W +
Sbjct: 169 SADMTIKLRDFQGFECIRTMH--GHDHNVSSVAIMPNGDH--IVSASRDKTIKMWEVQTG 224
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCF 362
GH ++ V + DG+L AS D +W + + L +H ++ + +
Sbjct: 225 YCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISW 284
Query: 361 SP 356
+P
Sbjct: 285 AP 286
>AF112205-1|AAF17193.1| 421|Homo sapiens WSB-1 protein protein.
Length = 421
Score = 66.1 bits (154), Expect = 1e-10
Identities = 51/193 (26%), Positives = 84/193 (43%), Gaps = 4/193 (2%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK 536
SRDKT+++W+ + GH +WV FSP+ + ++ S G + V +W++
Sbjct: 190 SRDKTLRVWDLKDDGNMMKVLRGHQNWVYSCAFSPDSS--MLCSVGASKAVFLWNMDKYT 247
Query: 535 LKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDIITALCFS- 359
+ GH + SPDG+L A+ D + +WD ++G L H F+
Sbjct: 248 MIRKLEGHHHDVVACDFSPDGALLATASYDTRVYIWDPHNGDILMEFGHLFPPPTPIFAG 307
Query: 358 -PNRYWL-CAAFG-PSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQT 188
N W+ +F + + L +MV R + Q + C A+STDG
Sbjct: 308 GANDRWVRSVSFSHDGLHVASLADDKMVRFWRIDEDYPVQVAPLSNGLC--CAFSTDGSV 365
Query: 187 LFAGYSDNTIRVW 149
L AG D ++ W
Sbjct: 366 LAAGTHDGSVYFW 378
Score = 61.7 bits (143), Expect = 3e-09
Identities = 48/197 (24%), Positives = 92/197 (46%), Gaps = 5/197 (2%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
G + IK+W+ K + H++ V + F+P+ + I+VS D+T++VW L +
Sbjct: 146 GLNNGRIKIWDVYTG-KLLLNLVDHTEVVRDLTFAPD-GSLILVSASRDKTLRVWDLKDD 203
Query: 538 KLKINHL-GHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALC 365
+ L GH ++ + SPD S+ S G LW+++ + L+ H+ + A
Sbjct: 204 GNMMKVLRGHQNWVYSCAFSPDSSMLCSVGASKAVFLWNMDKYTMIRKLEGHHHDVVACD 263
Query: 364 FSPNRYWLC-AAFGPSIKIWDLESKEMVEELRPEIINQTQ--TSKTDPPQCLSLAWSTDG 194
FSP+ L A++ + IWD + +++ E T + S+++S DG
Sbjct: 264 FSPDGALLATASYDTRVYIWDPHNGDILMEFGHLFPPPTPIFAGGANDRWVRSVSFSHDG 323
Query: 193 QTLFAGYSDNTIRVWQV 143
+ + D +R W++
Sbjct: 324 LHVASLADDKMVRFWRI 340
>AF072880-1|AAD28808.1| 421|Homo sapiens SOCS box-containing WD
protein SWiP-1 protein.
Length = 421
Score = 66.1 bits (154), Expect = 1e-10
Identities = 51/193 (26%), Positives = 84/193 (43%), Gaps = 4/193 (2%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK 536
SRDKT+++W+ + GH +WV FSP+ + ++ S G + V +W++
Sbjct: 190 SRDKTLRVWDLKDDGNMMKVLRGHQNWVYSCAFSPDSS--MLCSVGASKAVFLWNMDKYT 247
Query: 535 LKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDIITALCFS- 359
+ GH + SPDG+L A+ D + +WD ++G L H F+
Sbjct: 248 MIRKLEGHHHDVVACDFSPDGALLATASYDTRVYIWDPHNGDILMEFGHLFPPPTPIFAG 307
Query: 358 -PNRYWL-CAAFG-PSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQT 188
N W+ +F + + L +MV R + Q + C A+STDG
Sbjct: 308 GANDRWVRSVSFSHDGLHVASLADDKMVRFWRIDEDYPVQVAPLSNGLC--CAFSTDGSV 365
Query: 187 LFAGYSDNTIRVW 149
L AG D ++ W
Sbjct: 366 LAAGTHDGSVYFW 378
Score = 61.7 bits (143), Expect = 3e-09
Identities = 48/197 (24%), Positives = 92/197 (46%), Gaps = 5/197 (2%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
G + IK+W+ K + H++ V + F+P+ + I+VS D+T++VW L +
Sbjct: 146 GLNNGRIKIWDVYTG-KLLLNLVDHTEVVRDLTFAPD-GSLILVSASRDKTLRVWDLKDD 203
Query: 538 KLKINHL-GHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALC 365
+ L GH ++ + SPD S+ S G LW+++ + L+ H+ + A
Sbjct: 204 GNMMKVLRGHQNWVYSCAFSPDSSMLCSVGASKAVFLWNMDKYTMIRKLEGHHHDVVACD 263
Query: 364 FSPNRYWLC-AAFGPSIKIWDLESKEMVEELRPEIINQTQ--TSKTDPPQCLSLAWSTDG 194
FSP+ L A++ + IWD + +++ E T + S+++S DG
Sbjct: 264 FSPDGALLATASYDTRVYIWDPHNGDILMEFGHLFPPPTPIFAGGANDRWVRSVSFSHDG 323
Query: 193 QTLFAGYSDNTIRVWQV 143
+ + D +R W++
Sbjct: 324 LHVASLADDKMVRFWRI 340
>AF069313-1|AAD20954.2| 421|Homo sapiens WSB1 protein protein.
Length = 421
Score = 66.1 bits (154), Expect = 1e-10
Identities = 51/193 (26%), Positives = 84/193 (43%), Gaps = 4/193 (2%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK 536
SRDKT+++W+ + GH +WV FSP+ + ++ S G + V +W++
Sbjct: 190 SRDKTLRVWDLKDDGNMMKVLRGHQNWVYSCAFSPDSS--MLCSVGASKAVFLWNMDKYT 247
Query: 535 LKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDIITALCFS- 359
+ GH + SPDG+L A+ D + +WD ++G L H F+
Sbjct: 248 MIRKLEGHHHDVVACDFSPDGALLATASYDTRVYIWDPHNGDILMEFGHLFPPPTPIFAG 307
Query: 358 -PNRYWL-CAAFG-PSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQT 188
N W+ +F + + L +MV R + Q + C A+STDG
Sbjct: 308 GANDRWVRSVSFSHDGLHVASLADDKMVRFWRIDEDYPVQVAPLSNGLC--CAFSTDGSV 365
Query: 187 LFAGYSDNTIRVW 149
L AG D ++ W
Sbjct: 366 LAAGTHDGSVYFW 378
Score = 61.7 bits (143), Expect = 3e-09
Identities = 48/197 (24%), Positives = 92/197 (46%), Gaps = 5/197 (2%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
G + IK+W+ K + H++ V + F+P+ + I+VS D+T++VW L +
Sbjct: 146 GLNNGRIKIWDVYTG-KLLLNLVDHTEVVRDLTFAPD-GSLILVSASRDKTLRVWDLKDD 203
Query: 538 KLKINHL-GHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALC 365
+ L GH ++ + SPD S+ S G LW+++ + L+ H+ + A
Sbjct: 204 GNMMKVLRGHQNWVYSCAFSPDSSMLCSVGASKAVFLWNMDKYTMIRKLEGHHHDVVACD 263
Query: 364 FSPNRYWLC-AAFGPSIKIWDLESKEMVEELRPEIINQTQ--TSKTDPPQCLSLAWSTDG 194
FSP+ L A++ + IWD + +++ E T + S+++S DG
Sbjct: 264 FSPDGALLATASYDTRVYIWDPHNGDILMEFGHLFPPPTPIFAGGANDRWVRSVSFSHDG 323
Query: 193 QTLFAGYSDNTIRVWQV 143
+ + D +R W++
Sbjct: 324 LHVASLADDKMVRFWRI 340
>AF090988-1|AAC69625.1| 357|Homo sapiens U5 snRNP-specific 40 kDa
protein protein.
Length = 357
Score = 65.7 bits (153), Expect = 2e-10
Identities = 55/196 (28%), Positives = 88/196 (44%), Gaps = 4/196 (2%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQDDGHSDWV-SCVRFSPNHANPIIVSCGWDR-TVKVWHLTN 542
S DKT+ +W++ + + GH+ +V SC P +P +V G D TVK+W +
Sbjct: 128 STDKTVAVWDSETGERVK-RLKGHTSFVNSCY---PARKSPQLVCTGSDDGTVKLWDIRK 183
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALC 365
K I ++ + VT + SGG D +WDL K +T+ H D +T L
Sbjct: 184 -KAAIQTFQNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVTGLS 242
Query: 364 FSPN-RYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQT 188
S Y L A ++++WD+ + + R I Q + L +WS DG
Sbjct: 243 LSSEGSYLLSNAMDNTVRVWDV--RPFAPKERCVKIFQGNVHNFEK-NLLRCSWSPDGSK 299
Query: 187 LFAGYSDNTIRVWQVS 140
+ AG +D + VW +
Sbjct: 300 IAAGSADRFVYVWDTT 315
Score = 64.5 bits (150), Expect = 4e-10
Identities = 47/191 (24%), Positives = 77/191 (40%), Gaps = 2/191 (1%)
Frame = -2
Query: 709 DKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLK 530
D+ I LWN +C GHS V + + N ++ S D+TV VW +
Sbjct: 87 DRLILLWNVYGDCDNYATLKGHSGAVMELHY--NTDGSMLFSASTDKTVAVWDSETGERV 144
Query: 529 INHLGHSGYLNTV-TVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDIITALCFSPN 353
GH+ ++N+ L +G D LWD+ + T + + A+ F+
Sbjct: 145 KRLKGHTSFVNSCYPARKSPQLVCTGSDDGTVKLWDIRKKAAIQTFQNTYQVLAVTFNDT 204
Query: 352 RYWLCAA-FGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAG 176
+ + IK+WDL ++ T T + L+ S++G L +
Sbjct: 205 SDQIISGGIDNDIKVWDLRQNKL-----------TYTMRGHADSVTGLSLSSEGSYLLSN 253
Query: 175 YSDNTIRVWQV 143
DNT+RVW V
Sbjct: 254 AMDNTVRVWDV 264
Score = 61.7 bits (143), Expect = 3e-09
Identities = 40/173 (23%), Positives = 75/173 (43%), Gaps = 4/173 (2%)
Frame = -2
Query: 649 GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT-NCKLKINHLGHSGYLNTVTVSPDG 473
GH V C +F PN + + S G+DR + +W++ +C GHSG + + + DG
Sbjct: 64 GHEGEVYCCKFHPNGST--LASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTDG 121
Query: 472 SLCASGGKDMKAMLWDLNDGKHLHTLDHNDIITALCFSPNRYWLCAAFGP---SIKIWDL 302
S+ S D +WD G+ + L + C+ + G ++K+WD+
Sbjct: 122 SMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARKSPQLVCTGSDDGTVKLWDI 181
Query: 301 ESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQV 143
K ++ + + Q L++ ++ + +G DN I+VW +
Sbjct: 182 RKKAAIQTFQ------------NTYQVLAVTFNDTSDQIISGGIDNDIKVWDL 222
Score = 51.6 bits (118), Expect = 3e-06
Identities = 33/99 (33%), Positives = 48/99 (48%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
GS D T+KLW+ K IQ ++ V V F N + I+S G D +KVW L
Sbjct: 170 GSDDGTVKLWDIRK--KAAIQTFQNTYQVLAVTF--NDTSDQIISGGIDNDIKVWDLRQN 225
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDL 422
KL GH+ + +++S +GS S D +WD+
Sbjct: 226 KLTYTMRGHADSVTGLSLSSEGSYLLSNAMDNTVRVWDV 264
Score = 43.2 bits (97), Expect = 0.001
Identities = 38/131 (29%), Positives = 57/131 (43%), Gaps = 9/131 (6%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT-- 545
G D IK+W+ L + K T GH+D V+ + S + ++S D TV+VW +
Sbjct: 211 GGIDNDIKVWD-LRQNKLTYTMRGHADSVTGLSLSSEGS--YLLSNAMDNTVRVWDVRPF 267
Query: 544 ----NCKLKINHLGHSGYLNTVTVS--PDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHN 386
C H+ N + S PDGS A+G D +WD + L+ L H
Sbjct: 268 APKERCVKIFQGNVHNFEKNLLRCSWSPDGSKIAAGSADRFVYVWDTTSRRILYKLPGHA 327
Query: 385 DIITALCFSPN 353
I + F P+
Sbjct: 328 GSINEVAFHPD 338
Score = 37.5 bits (83), Expect = 0.048
Identities = 24/101 (23%), Positives = 44/101 (43%), Gaps = 5/101 (4%)
Frame = -2
Query: 709 DKTIKLWNTLA-----ECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 545
D T+++W+ C Q + H+ + +R S + I + DR V VW T
Sbjct: 256 DNTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRCSWSPDGSKIAAGSADRFVYVWDTT 315
Query: 544 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDL 422
+ ++ GH+G +N V PD + S D + + ++
Sbjct: 316 SRRILYKLPGHAGSINEVAFHPDEPIIISASSDKRLYMGEI 356
Score = 29.9 bits (64), Expect = 9.6
Identities = 14/42 (33%), Positives = 21/42 (50%)
Frame = -2
Query: 220 LSLAWSTDGQTLFAGYSDNTIRVWQVSISAR*A*LSTLISFI 95
+ L ++TDG LF+ +D T+ VW R L SF+
Sbjct: 113 MELHYNTDGSMLFSASTDKTVAVWDSETGERVKRLKGHTSFV 154
>AF083383-1|AAC64084.1| 310|Homo sapiens 38kDa splicing factor
protein.
Length = 310
Score = 65.7 bits (153), Expect = 2e-10
Identities = 48/191 (25%), Positives = 79/191 (41%), Gaps = 2/191 (1%)
Frame = -2
Query: 709 DKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLK 530
D+ I LWN +C GHS V + + N ++ S D+TV VW +
Sbjct: 28 DRLILLWNVYGDCDNYATLKGHSGAVMELHY--NTDGSMLFSASTDKTVAVWDSETGERV 85
Query: 529 INHLGHSGYLNTVTVSPDG-SLCASGGKDMKAMLWDLNDGKHLHTLDHNDIITALCFSPN 353
GH+ ++N+ + G L +G D LWD+ + T + + A+ F+
Sbjct: 86 KRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDIRKKAAVQTFQNTYQVLAVTFNDT 145
Query: 352 RYWLCAA-FGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAG 176
+ + IK+WDL ++ T T + L+ S++G L +
Sbjct: 146 SDQIISGGIDNDIKVWDLRQNKL-----------TYTMRGHADSVTGLSLSSEGSYLLSN 194
Query: 175 YSDNTIRVWQV 143
DNT+RVW V
Sbjct: 195 AMDNTVRVWDV 205
Score = 64.9 bits (151), Expect = 3e-10
Identities = 54/196 (27%), Positives = 87/196 (44%), Gaps = 4/196 (2%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQDDGHSDWV-SCVRFSPNHANPIIVSCGWDR-TVKVWHLTN 542
S DKT+ +W++ + + GH+ +V SC P P +V G D TVK+W +
Sbjct: 69 STDKTVAVWDSETGERVK-RLKGHTSFVNSCY---PARRGPQLVCTGSDDGTVKLWDIRK 124
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALC 365
K + ++ + VT + SGG D +WDL K +T+ H D +T L
Sbjct: 125 -KAAVQTFQNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVTGLS 183
Query: 364 FSPN-RYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQT 188
S Y L A ++++WD+ + + R I Q + L +WS DG
Sbjct: 184 LSSEGSYLLSNAMDNTVRVWDV--RPFAPKERCVKIFQGNVHNFEK-NLLRCSWSPDGSK 240
Query: 187 LFAGYSDNTIRVWQVS 140
+ AG +D + VW +
Sbjct: 241 IAAGSADRFVYVWDTT 256
Score = 63.3 bits (147), Expect = 8e-10
Identities = 42/173 (24%), Positives = 76/173 (43%), Gaps = 4/173 (2%)
Frame = -2
Query: 649 GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT-NCKLKINHLGHSGYLNTVTVSPDG 473
GH V C +F PN + + S G+DR + +W++ +C GHSG + + + DG
Sbjct: 5 GHEGEVYCCKFHPNGST--LASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTDG 62
Query: 472 SLCASGGKDMKAMLWDLNDGKHLHTLDHNDIITALCFSPNR--YWLCAAFGP-SIKIWDL 302
S+ S D +WD G+ + L + C+ R +C ++K+WD+
Sbjct: 63 SMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDI 122
Query: 301 ESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQV 143
K V+ + + Q L++ ++ + +G DN I+VW +
Sbjct: 123 RKKAAVQTFQ------------NTYQVLAVTFNDTSDQIISGGIDNDIKVWDL 163
Score = 51.2 bits (117), Expect = 4e-06
Identities = 32/99 (32%), Positives = 48/99 (48%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
GS D T+KLW+ K +Q ++ V V F N + I+S G D +KVW L
Sbjct: 111 GSDDGTVKLWDIRK--KAAVQTFQNTYQVLAVTF--NDTSDQIISGGIDNDIKVWDLRQN 166
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDL 422
KL GH+ + +++S +GS S D +WD+
Sbjct: 167 KLTYTMRGHADSVTGLSLSSEGSYLLSNAMDNTVRVWDV 205
Score = 29.9 bits (64), Expect = 9.6
Identities = 14/42 (33%), Positives = 21/42 (50%)
Frame = -2
Query: 220 LSLAWSTDGQTLFAGYSDNTIRVWQVSISAR*A*LSTLISFI 95
+ L ++TDG LF+ +D T+ VW R L SF+
Sbjct: 54 MELHYNTDGSMLFSASTDKTVAVWDSETGERVKRLKGHTSFV 95
>U72342-1|AAC51111.1| 410|Homo sapiens platelet activating factor
acetylhydrolase, brain isoform, 45 kDa subunit protein.
Length = 410
Score = 65.3 bits (152), Expect = 2e-10
Identities = 50/206 (24%), Positives = 94/206 (45%), Gaps = 14/206 (6%)
Frame = -2
Query: 715 SRDKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
S D TIK+W+ + + T++ GH+D V + F +H+ ++ SC D T+K+W
Sbjct: 127 SEDATIKVWDYETGDFERTLK--GHTDSVQDISF--DHSGKLLASCSADMTIKLWDFQGF 182
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCF 362
+ GH +++V + P+G S +D +W++ G + T H + + +
Sbjct: 183 ECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMV-- 240
Query: 361 SPNRYWLCAAF---GPSIKIWDLESKEMVEELR--PEIINQTQTSKTDPPQCLSLAWSTD 197
PN+ A ++++W + +KE ELR ++ + +S A ++
Sbjct: 241 RPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSE 300
Query: 196 -------GQTLFAGYSDNTIRVWQVS 140
G L +G D TI++W VS
Sbjct: 301 TKKSGKPGPFLLSGSRDKTIKMWDVS 326
Score = 54.8 bits (126), Expect = 3e-07
Identities = 47/188 (25%), Positives = 83/188 (44%), Gaps = 2/188 (1%)
Frame = -2
Query: 697 KLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHL 518
K W KY + GH V+ V F P + ++VS D T+KVW +
Sbjct: 92 KEWIPRPPEKYALS--GHRSPVTRVIFHPVFS--VMVSASEDATIKVWDYETGDFERTLK 147
Query: 517 GHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCFSPN-RYW 344
GH+ + ++ G L AS DM LWD + + T+ H+ ++++ PN +
Sbjct: 148 GHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHI 207
Query: 343 LCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDN 164
+ A+ +IK+W++++ V+ ++ P Q DG + + +D
Sbjct: 208 VSASRDKTIKMWEVQTGYCVKTFTG---HREWVRMVRPNQ--------DGTLIASCSNDQ 256
Query: 163 TIRVWQVS 140
T+RVW V+
Sbjct: 257 TVRVWVVA 264
Score = 53.2 bits (122), Expect = 9e-07
Identities = 29/99 (29%), Positives = 47/99 (47%), Gaps = 1/99 (1%)
Frame = -2
Query: 718 GSRDKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
GSRDKTIK+W+ + C T+ GH +WV V F + I+SC D+T++VW N
Sbjct: 314 GSRDKTIKMWDVSTGMCLMTLV--GHDNWVRGVLF--HSGGKFILSCADDKTLRVWDYKN 369
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWD 425
+ H ++ ++ +G D +W+
Sbjct: 370 KRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWE 408
Score = 50.0 bits (114), Expect = 8e-06
Identities = 34/158 (21%), Positives = 69/158 (43%), Gaps = 21/158 (13%)
Frame = -2
Query: 715 SRDKTIKLWNTLA-ECKYTIQDDGHSDWVSCVRFSPNHA------------------NPI 593
S D+T+++W ECK +++ H V C+ ++P + P
Sbjct: 253 SNDQTVRVWVVATKECKAELRE--HEHVVECISWAPESSYSSISEATGSETKKSGKPGPF 310
Query: 592 IVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDG 413
++S D+T+K+W ++ + +GH ++ V G S D +WD +
Sbjct: 311 LLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNK 370
Query: 412 KHLHTLD-HNDIITALCFSPNR-YWLCAAFGPSIKIWD 305
+ + TL+ H +T+L F Y + + ++K+W+
Sbjct: 371 RCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWE 408
>L13387-1|AAA02882.1| 288|Homo sapiens Miller-Dieker lissencephaly
protein protein.
Length = 288
Score = 65.3 bits (152), Expect = 2e-10
Identities = 50/206 (24%), Positives = 94/206 (45%), Gaps = 14/206 (6%)
Frame = -2
Query: 715 SRDKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
S D TIK+W+ + + T++ GH+D V + F +H+ ++ SC D T+K+W
Sbjct: 5 SEDATIKVWDYETGDFERTLK--GHTDSVQDISF--DHSGKLLASCSADMTIKLWDFQGF 60
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCF 362
+ GH +++V + P+G S +D +W++ G + T H + + +
Sbjct: 61 ECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMV-- 118
Query: 361 SPNRYWLCAAF---GPSIKIWDLESKEMVEELR--PEIINQTQTSKTDPPQCLSLAWSTD 197
PN+ A ++++W + +KE ELR ++ + +S A ++
Sbjct: 119 RPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSE 178
Query: 196 -------GQTLFAGYSDNTIRVWQVS 140
G L +G D TI++W VS
Sbjct: 179 TKKSGKPGPFLLSGSRDKTIKMWDVS 204
Score = 52.0 bits (119), Expect = 2e-06
Identities = 29/99 (29%), Positives = 46/99 (46%), Gaps = 1/99 (1%)
Frame = -2
Query: 718 GSRDKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
GSRDKTIK+W+ + C T GH +WV V F + I+SC D+T++VW N
Sbjct: 192 GSRDKTIKMWDVSTGMCLMTXV--GHDNWVRGVLF--HSGGKFILSCADDKTLRVWDYKN 247
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWD 425
+ H ++ ++ +G D +W+
Sbjct: 248 KRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWE 286
Score = 50.8 bits (116), Expect = 5e-06
Identities = 34/158 (21%), Positives = 69/158 (43%), Gaps = 21/158 (13%)
Frame = -2
Query: 715 SRDKTIKLWNTLA-ECKYTIQDDGHSDWVSCVRFSPNHA------------------NPI 593
S D+T+++W ECK +++ H V C+ ++P + P
Sbjct: 131 SNDQTVRVWVVATKECKAELRE--HEHVVECISWAPESSYSSISEATGSETKKSGKPGPF 188
Query: 592 IVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDG 413
++S D+T+K+W ++ + +GH ++ V G S D +WD +
Sbjct: 189 LLSGSRDKTIKMWDVSTGMCLMTXVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNK 248
Query: 412 KHLHTLD-HNDIITALCFSPNR-YWLCAAFGPSIKIWD 305
+ + TL+ H +T+L F Y + + ++K+W+
Sbjct: 249 RCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWE 286
Score = 49.6 bits (113), Expect = 1e-05
Identities = 37/153 (24%), Positives = 69/153 (45%), Gaps = 2/153 (1%)
Frame = -2
Query: 592 IVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDG 413
+VS D T+KVW + GH+ + ++ G L AS DM LWD
Sbjct: 1 MVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGF 60
Query: 412 KHLHTL-DHNDIITALCFSPN-RYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSK 239
+ + T+ H+ ++++ PN + + A+ +IK+W++++ V+ ++
Sbjct: 61 ECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTG---HREWVRM 117
Query: 238 TDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQVS 140
P Q DG + + +D T+RVW V+
Sbjct: 118 VRPNQ--------DGTLIASCSNDQTVRVWVVA 142
>L13386-1|AAA02881.1| 410|Homo sapiens Miller-Dieker lissencephaly
protein protein.
Length = 410
Score = 65.3 bits (152), Expect = 2e-10
Identities = 50/206 (24%), Positives = 94/206 (45%), Gaps = 14/206 (6%)
Frame = -2
Query: 715 SRDKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
S D TIK+W+ + + T++ GH+D V + F +H+ ++ SC D T+K+W
Sbjct: 127 SEDATIKVWDYETGDFERTLK--GHTDSVQDISF--DHSGKLLASCSADMTIKLWDFQGF 182
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCF 362
+ GH +++V + P+G S +D +W++ G + T H + + +
Sbjct: 183 ECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMV-- 240
Query: 361 SPNRYWLCAAF---GPSIKIWDLESKEMVEELR--PEIINQTQTSKTDPPQCLSLAWSTD 197
PN+ A ++++W + +KE ELR ++ + +S A ++
Sbjct: 241 RPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSE 300
Query: 196 -------GQTLFAGYSDNTIRVWQVS 140
G L +G D TI++W VS
Sbjct: 301 TKKSGKPGPFLLSGSRDKTIKMWDVS 326
Score = 54.8 bits (126), Expect = 3e-07
Identities = 47/188 (25%), Positives = 83/188 (44%), Gaps = 2/188 (1%)
Frame = -2
Query: 697 KLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHL 518
K W KY + GH V+ V F P + ++VS D T+KVW +
Sbjct: 92 KEWIPRPPEKYALS--GHRSPVTRVIFHPVFS--VMVSASEDATIKVWDYETGDFERTLK 147
Query: 517 GHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCFSPN-RYW 344
GH+ + ++ G L AS DM LWD + + T+ H+ ++++ PN +
Sbjct: 148 GHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHI 207
Query: 343 LCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDN 164
+ A+ +IK+W++++ V+ ++ P Q DG + + +D
Sbjct: 208 VSASRDKTIKMWEVQTGYCVKTFTG---HREWVRMVRPNQ--------DGTLIASCSNDQ 256
Query: 163 TIRVWQVS 140
T+RVW V+
Sbjct: 257 TVRVWVVA 264
Score = 53.2 bits (122), Expect = 9e-07
Identities = 29/99 (29%), Positives = 47/99 (47%), Gaps = 1/99 (1%)
Frame = -2
Query: 718 GSRDKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
GSRDKTIK+W+ + C T+ GH +WV V F + I+SC D+T++VW N
Sbjct: 314 GSRDKTIKMWDVSTGMCLMTLV--GHDNWVRGVLF--HSGGKFILSCADDKTLRVWDYKN 369
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWD 425
+ H ++ ++ +G D +W+
Sbjct: 370 KRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWE 408
Score = 50.0 bits (114), Expect = 8e-06
Identities = 34/158 (21%), Positives = 69/158 (43%), Gaps = 21/158 (13%)
Frame = -2
Query: 715 SRDKTIKLWNTLA-ECKYTIQDDGHSDWVSCVRFSPNHA------------------NPI 593
S D+T+++W ECK +++ H V C+ ++P + P
Sbjct: 253 SNDQTVRVWVVATKECKAELRE--HEHVVECISWAPESSYSSISEATGSETKKSGKPGPF 310
Query: 592 IVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDG 413
++S D+T+K+W ++ + +GH ++ V G S D +WD +
Sbjct: 311 LLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNK 370
Query: 412 KHLHTLD-HNDIITALCFSPNR-YWLCAAFGPSIKIWD 305
+ + TL+ H +T+L F Y + + ++K+W+
Sbjct: 371 RCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWE 408
>L13385-1|AAA02880.1| 410|Homo sapiens Miller-Dieker lissencephaly
protein protein.
Length = 410
Score = 65.3 bits (152), Expect = 2e-10
Identities = 50/206 (24%), Positives = 94/206 (45%), Gaps = 14/206 (6%)
Frame = -2
Query: 715 SRDKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
S D TIK+W+ + + T++ GH+D V + F +H+ ++ SC D T+K+W
Sbjct: 127 SEDATIKVWDYETGDFERTLK--GHTDSVQDISF--DHSGKLLASCSADMTIKLWDFQGF 182
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCF 362
+ GH +++V + P+G S +D +W++ G + T H + + +
Sbjct: 183 ECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMV-- 240
Query: 361 SPNRYWLCAAF---GPSIKIWDLESKEMVEELR--PEIINQTQTSKTDPPQCLSLAWSTD 197
PN+ A ++++W + +KE ELR ++ + +S A ++
Sbjct: 241 RPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSE 300
Query: 196 -------GQTLFAGYSDNTIRVWQVS 140
G L +G D TI++W VS
Sbjct: 301 TKKSGKPGPFLLSGSRDKTIKMWDVS 326
Score = 54.8 bits (126), Expect = 3e-07
Identities = 47/188 (25%), Positives = 83/188 (44%), Gaps = 2/188 (1%)
Frame = -2
Query: 697 KLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHL 518
K W KY + GH V+ V F P + ++VS D T+KVW +
Sbjct: 92 KEWIPRPPEKYALS--GHRSPVTRVIFHPVFS--VMVSASEDATIKVWDYETGDFERTLK 147
Query: 517 GHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCFSPN-RYW 344
GH+ + ++ G L AS DM LWD + + T+ H+ ++++ PN +
Sbjct: 148 GHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHI 207
Query: 343 LCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDN 164
+ A+ +IK+W++++ V+ ++ P Q DG + + +D
Sbjct: 208 VSASRDKTIKMWEVQTGYCVKTFTG---HREWVRMVRPNQ--------DGTLIASCSNDQ 256
Query: 163 TIRVWQVS 140
T+RVW V+
Sbjct: 257 TVRVWVVA 264
Score = 53.2 bits (122), Expect = 9e-07
Identities = 29/99 (29%), Positives = 47/99 (47%), Gaps = 1/99 (1%)
Frame = -2
Query: 718 GSRDKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
GSRDKTIK+W+ + C T+ GH +WV V F + I+SC D+T++VW N
Sbjct: 314 GSRDKTIKMWDVSTGMCLMTLV--GHDNWVRGVLF--HSGGKFILSCADDKTLRVWDYKN 369
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWD 425
+ H ++ ++ +G D +W+
Sbjct: 370 KRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWE 408
Score = 50.0 bits (114), Expect = 8e-06
Identities = 34/158 (21%), Positives = 69/158 (43%), Gaps = 21/158 (13%)
Frame = -2
Query: 715 SRDKTIKLWNTLA-ECKYTIQDDGHSDWVSCVRFSPNHA------------------NPI 593
S D+T+++W ECK +++ H V C+ ++P + P
Sbjct: 253 SNDQTVRVWVVATKECKAELRE--HEHVVECISWAPESSYSSISEATGSETKKSGKPGPF 310
Query: 592 IVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDG 413
++S D+T+K+W ++ + +GH ++ V G S D +WD +
Sbjct: 311 LLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNK 370
Query: 412 KHLHTLD-HNDIITALCFSPNR-YWLCAAFGPSIKIWD 305
+ + TL+ H +T+L F Y + + ++K+W+
Sbjct: 371 RCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWE 408
>BC064638-1|AAH64638.1| 410|Homo sapiens platelet-activating factor
acetylhydrolase, isoform Ib, alpha subunit 45kDa
protein.
Length = 410
Score = 65.3 bits (152), Expect = 2e-10
Identities = 50/206 (24%), Positives = 94/206 (45%), Gaps = 14/206 (6%)
Frame = -2
Query: 715 SRDKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
S D TIK+W+ + + T++ GH+D V + F +H+ ++ SC D T+K+W
Sbjct: 127 SEDATIKVWDYETGDFERTLK--GHTDSVQDISF--DHSGKLLASCSADMTIKLWDFQGF 182
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCF 362
+ GH +++V + P+G S +D +W++ G + T H + + +
Sbjct: 183 ECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMV-- 240
Query: 361 SPNRYWLCAAF---GPSIKIWDLESKEMVEELR--PEIINQTQTSKTDPPQCLSLAWSTD 197
PN+ A ++++W + +KE ELR ++ + +S A ++
Sbjct: 241 RPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSE 300
Query: 196 -------GQTLFAGYSDNTIRVWQVS 140
G L +G D TI++W VS
Sbjct: 301 TKKSGKPGPFLLSGSRDKTIKMWDVS 326
Score = 54.8 bits (126), Expect = 3e-07
Identities = 47/188 (25%), Positives = 83/188 (44%), Gaps = 2/188 (1%)
Frame = -2
Query: 697 KLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHL 518
K W KY + GH V+ V F P + ++VS D T+KVW +
Sbjct: 92 KEWIPRPPEKYALS--GHRSPVTRVIFHPVFS--VMVSASEDATIKVWDYETGDFERTLK 147
Query: 517 GHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCFSPN-RYW 344
GH+ + ++ G L AS DM LWD + + T+ H+ ++++ PN +
Sbjct: 148 GHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHI 207
Query: 343 LCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDN 164
+ A+ +IK+W++++ V+ ++ P Q DG + + +D
Sbjct: 208 VSASRDKTIKMWEVQTGYCVKTFTG---HREWVRMVRPNQ--------DGTLIASCSNDQ 256
Query: 163 TIRVWQVS 140
T+RVW V+
Sbjct: 257 TVRVWVVA 264
Score = 53.2 bits (122), Expect = 9e-07
Identities = 29/99 (29%), Positives = 47/99 (47%), Gaps = 1/99 (1%)
Frame = -2
Query: 718 GSRDKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
GSRDKTIK+W+ + C T+ GH +WV V F + I+SC D+T++VW N
Sbjct: 314 GSRDKTIKMWDVSTGMCLMTLV--GHDNWVRGVLF--HSGGKFILSCADDKTLRVWDYKN 369
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWD 425
+ H ++ ++ +G D +W+
Sbjct: 370 KRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWE 408
Score = 50.0 bits (114), Expect = 8e-06
Identities = 34/158 (21%), Positives = 69/158 (43%), Gaps = 21/158 (13%)
Frame = -2
Query: 715 SRDKTIKLWNTLA-ECKYTIQDDGHSDWVSCVRFSPNHA------------------NPI 593
S D+T+++W ECK +++ H V C+ ++P + P
Sbjct: 253 SNDQTVRVWVVATKECKAELRE--HEHVVECISWAPESSYSSISEATGSETKKSGKPGPF 310
Query: 592 IVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDG 413
++S D+T+K+W ++ + +GH ++ V G S D +WD +
Sbjct: 311 LLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNK 370
Query: 412 KHLHTLD-HNDIITALCFSPNR-YWLCAAFGPSIKIWD 305
+ + TL+ H +T+L F Y + + ++K+W+
Sbjct: 371 RCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWE 408
>BC035409-1|AAH35409.1| 808|Homo sapiens transducin (beta)-like 3
protein.
Length = 808
Score = 65.3 bits (152), Expect = 2e-10
Identities = 44/150 (29%), Positives = 69/150 (46%), Gaps = 3/150 (2%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
GS+D+T KLW L +C+ GH + CV+FSP + ++ + D T+K+W L +
Sbjct: 497 GSQDRTAKLW-ALPQCQLLGVFSGHRRGLWCVQFSP--MDQVLATASADGTIKLWALQDF 553
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITAL-C 365
GH + V G+ S G D LW + + + + TLD H D + L C
Sbjct: 554 SCLKTFEGHDASVLKVAFVSRGTQLLSSGSDGLVKLWTIKNNECVRTLDAHEDKVWGLHC 613
Query: 364 FSPNRYWLCAAFGPSIKIW-DLESKEMVEE 278
+ + L A + +W D+ E EE
Sbjct: 614 SRLDDHALTGASDSRVILWKDVTEAEQAEE 643
Score = 52.8 bits (121), Expect = 1e-06
Identities = 45/164 (27%), Positives = 69/164 (42%), Gaps = 16/164 (9%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAEC--KYTIQDDG------------HSDWVSCVRFSPNHANPIIVSC 581
GS+D T+KLW K T D+G H ++ V +PN + ++ +
Sbjct: 440 GSQDCTVKLWPLPKALLSKNTAPDNGPILLQAQTTQRCHDKDINSVAIAPN--DKLLATG 497
Query: 580 GWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLH 401
DRT K+W L C+L GH L V SP + A+ D LW L D L
Sbjct: 498 SQDRTAKLWALPQCQLLGVFSGHRRGLWCVQFSPMDQVLATASADGTIKLWALQDFSCLK 557
Query: 400 TLDHND--IITALCFSPNRYWLCAAFGPSIKIWDLESKEMVEEL 275
T + +D ++ S L + +K+W +++ E V L
Sbjct: 558 TFEGHDASVLKVAFVSRGTQLLSSGSDGLVKLWTIKNNECVRTL 601
Score = 47.6 bits (108), Expect = 4e-05
Identities = 41/174 (23%), Positives = 74/174 (42%), Gaps = 5/174 (2%)
Frame = -2
Query: 646 HSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGS- 470
H+ V+ + F P + ++ + G D V+VW + + G G ++ V PD +
Sbjct: 108 HTAPVATMAFDPT--STLLATGGCDGAVRVWDIVRHYGTHHFRGSPGVVHLVAFHPDPTR 165
Query: 469 -LCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALCFSPNRYWLCAAFGPSI-KIWDLE 299
L S D +W L D L L H +T+L FS + + + ++ I IWDL+
Sbjct: 166 LLLFSSATDAAIRVWSLQDRSCLAVLTAHYSAVTSLAFSADGHTMLSSGRDKICIIWDLQ 225
Query: 298 SKEMVEELRPEIINQTQTSKTDPPQCLS-LAWSTDGQTLFAGYSDNTIRVWQVS 140
S + + + + + P + +S L + G T+RVW+ +
Sbjct: 226 SCQATRTV--PVFESVEAAVLLPEEPVSQLGVKSPGLYFLTAGDQGTLRVWEAA 277
Score = 44.4 bits (100), Expect = 4e-04
Identities = 34/157 (21%), Positives = 62/157 (39%), Gaps = 12/157 (7%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
G D +++W+ + T G V V F P+ ++ S D ++VW L +
Sbjct: 127 GGCDGAVRVWDIVRHYG-THHFRGSPGVVHLVAFHPDPTRLLLFSSATDAAIRVWSLQDR 185
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDIITALCF- 362
H + ++ S DG S G+D ++WDL + T+ + + A
Sbjct: 186 SCLAVLTAHYSAVTSLAFSADGHTMLSSGRDKICIIWDLQSCQATRTVPVFESVEAAVLL 245
Query: 361 -----------SPNRYWLCAAFGPSIKIWDLESKEMV 284
SP Y+L A ++++W+ S + V
Sbjct: 246 PEEPVSQLGVKSPGLYFLTAGDQGTLRVWEAASGQCV 282
Score = 43.6 bits (98), Expect = 7e-04
Identities = 40/177 (22%), Positives = 74/177 (41%), Gaps = 10/177 (5%)
Frame = -2
Query: 649 GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGS 470
G+S+ V VRF + ++V+ +KV+ L +I H GH+ + + V G
Sbjct: 332 GYSEEVLDVRFLGPEDSHVVVASN-SPCLKVFELQTSACQILH-GHTDIVLALDVFRKGW 389
Query: 469 LCASGGKDMKAMLWDLNDGKHLHTL----DHNDIITALCFS--PNRYWLCAAFGPSIKIW 308
L AS KD +W +N + + H + +C S + + + ++K+W
Sbjct: 390 LFASCAKDQSVRIWRMNKAGQVMCVAQGSGHTHSVGTVCCSRLKESFLVTGSQDCTVKLW 449
Query: 307 DLE----SKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVW 149
L SK + P ++ T + S+A + + + L G D T ++W
Sbjct: 450 PLPKALLSKNTAPDNGPILLQAQTTQRCHDKDINSVAIAPNDKLLATGSQDRTAKLW 506
>BC014007-1|AAH14007.1| 808|Homo sapiens TBL3 protein protein.
Length = 808
Score = 65.3 bits (152), Expect = 2e-10
Identities = 44/150 (29%), Positives = 69/150 (46%), Gaps = 3/150 (2%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
GS+D+T KLW L +C+ GH + CV+FSP + ++ + D T+K+W L +
Sbjct: 497 GSQDRTAKLW-ALPQCQLLGVFSGHRRGLWCVQFSP--MDQVLATASADGTIKLWALQDF 553
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITAL-C 365
GH + V G+ S G D LW + + + + TLD H D + L C
Sbjct: 554 SCLKTFEGHDASVLKVAFVSRGTQLLSSGSDGLVKLWTIKNNECVRTLDAHEDKVWGLHC 613
Query: 364 FSPNRYWLCAAFGPSIKIW-DLESKEMVEE 278
+ + L A + +W D+ E EE
Sbjct: 614 SRLDDHALTGASDSRVILWKDVTEAEQAEE 643
Score = 52.8 bits (121), Expect = 1e-06
Identities = 45/164 (27%), Positives = 69/164 (42%), Gaps = 16/164 (9%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAEC--KYTIQDDG------------HSDWVSCVRFSPNHANPIIVSC 581
GS+D T+KLW K T D+G H ++ V +PN + ++ +
Sbjct: 440 GSQDCTVKLWPLPKALLSKNTAPDNGPILLQAQTTQRCHDKDINSVAIAPN--DKLLATG 497
Query: 580 GWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLH 401
DRT K+W L C+L GH L V SP + A+ D LW L D L
Sbjct: 498 SQDRTAKLWALPQCQLLGVFSGHRRGLWCVQFSPMDQVLATASADGTIKLWALQDFSCLK 557
Query: 400 TLDHND--IITALCFSPNRYWLCAAFGPSIKIWDLESKEMVEEL 275
T + +D ++ S L + +K+W +++ E V L
Sbjct: 558 TFEGHDASVLKVAFVSRGTQLLSSGSDGLVKLWTIKNNECVRTL 601
Score = 47.6 bits (108), Expect = 4e-05
Identities = 41/174 (23%), Positives = 74/174 (42%), Gaps = 5/174 (2%)
Frame = -2
Query: 646 HSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGS- 470
H+ V+ + F P + ++ + G D V+VW + + G G ++ V PD +
Sbjct: 108 HTAPVATMAFDPT--STLLATGGCDGAVRVWDIVRHYGTHHFRGSPGVVHLVAFHPDPTR 165
Query: 469 -LCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALCFSPNRYWLCAAFGPSI-KIWDLE 299
L S D +W L D L L H +T+L FS + + + ++ I IWDL+
Sbjct: 166 LLLFSSATDAAIRVWSLQDRSCLAVLTAHYSAVTSLAFSADGHTMLSSGRDKICIIWDLQ 225
Query: 298 SKEMVEELRPEIINQTQTSKTDPPQCLS-LAWSTDGQTLFAGYSDNTIRVWQVS 140
S + + + + + P + +S L + G T+RVW+ +
Sbjct: 226 SCQATRTV--PVFESVEAAVLLPEEPVSQLGVKSPGLYFLTAGDQGTLRVWEAA 277
Score = 44.4 bits (100), Expect = 4e-04
Identities = 34/157 (21%), Positives = 62/157 (39%), Gaps = 12/157 (7%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
G D +++W+ + T G V V F P+ ++ S D ++VW L +
Sbjct: 127 GGCDGAVRVWDIVRHYG-THHFRGSPGVVHLVAFHPDPTRLLLFSSATDAAIRVWSLQDR 185
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDIITALCF- 362
H + ++ S DG S G+D ++WDL + T+ + + A
Sbjct: 186 SCLAVLTAHYSAVTSLAFSADGHTMLSSGRDKICIIWDLQSCQATRTVPVFESVEAAVLL 245
Query: 361 -----------SPNRYWLCAAFGPSIKIWDLESKEMV 284
SP Y+L A ++++W+ S + V
Sbjct: 246 PEEPVSQLGVKSPGLYFLTAGDQGTLRVWEAASGQCV 282
Score = 43.6 bits (98), Expect = 7e-04
Identities = 40/177 (22%), Positives = 74/177 (41%), Gaps = 10/177 (5%)
Frame = -2
Query: 649 GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGS 470
G+S+ V VRF + ++V+ +KV+ L +I H GH+ + + V G
Sbjct: 332 GYSEEVLDVRFLGPEDSHVVVASN-SPCLKVFELQTSACQILH-GHTDIVLALDVFRKGW 389
Query: 469 LCASGGKDMKAMLWDLNDGKHLHTL----DHNDIITALCFS--PNRYWLCAAFGPSIKIW 308
L AS KD +W +N + + H + +C S + + + ++K+W
Sbjct: 390 LFASCAKDQSVRIWRMNKAGQVMCVAQGSGHTHSVGTVCCSRLKESFLVTGSQDCTVKLW 449
Query: 307 DLE----SKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVW 149
L SK + P ++ T + S+A + + + L G D T ++W
Sbjct: 450 PLPKALLSKNTAPDNGPILLQAQTTQRCHDKDINSVAIAPNDKLLATGSQDRTAKLW 506
>BC010231-1|AAH10231.1| 808|Homo sapiens transducin (beta)-like 3
protein.
Length = 808
Score = 65.3 bits (152), Expect = 2e-10
Identities = 44/150 (29%), Positives = 69/150 (46%), Gaps = 3/150 (2%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
GS+D+T KLW L +C+ GH + CV+FSP + ++ + D T+K+W L +
Sbjct: 497 GSQDRTAKLW-ALPQCQLLGVFSGHRRGLWCVQFSP--MDQVLATASADGTIKLWALQDF 553
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITAL-C 365
GH + V G+ S G D LW + + + + TLD H D + L C
Sbjct: 554 SCLKTFEGHDASVLKVAFVSRGTQLLSSGSDGLVKLWTIKNNECVRTLDAHEDKVWGLHC 613
Query: 364 FSPNRYWLCAAFGPSIKIW-DLESKEMVEE 278
+ + L A + +W D+ E EE
Sbjct: 614 SRLDDHALTGASDSRVILWKDVTEAEQAEE 643
Score = 52.8 bits (121), Expect = 1e-06
Identities = 45/164 (27%), Positives = 69/164 (42%), Gaps = 16/164 (9%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAEC--KYTIQDDG------------HSDWVSCVRFSPNHANPIIVSC 581
GS+D T+KLW K T D+G H ++ V +PN + ++ +
Sbjct: 440 GSQDCTVKLWPLPKALLSKNTAPDNGPILLQAQTTQRCHDKDINSVAIAPN--DKLLATG 497
Query: 580 GWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLH 401
DRT K+W L C+L GH L V SP + A+ D LW L D L
Sbjct: 498 SQDRTAKLWALPQCQLLGVFSGHRRGLWCVQFSPMDQVLATASADGTIKLWALQDFSCLK 557
Query: 400 TLDHND--IITALCFSPNRYWLCAAFGPSIKIWDLESKEMVEEL 275
T + +D ++ S L + +K+W +++ E V L
Sbjct: 558 TFEGHDASVLKVAFVSRGTQLLSSGSDGLVKLWTIKNNECVRTL 601
Score = 47.6 bits (108), Expect = 4e-05
Identities = 41/174 (23%), Positives = 74/174 (42%), Gaps = 5/174 (2%)
Frame = -2
Query: 646 HSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGS- 470
H+ V+ + F P + ++ + G D V+VW + + G G ++ V PD +
Sbjct: 108 HTAPVATMAFDPT--STLLATGGCDGAVRVWDIVRHYGTHHFRGSPGVVHLVAFHPDPTR 165
Query: 469 -LCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALCFSPNRYWLCAAFGPSI-KIWDLE 299
L S D +W L D L L H +T+L FS + + + ++ I IWDL+
Sbjct: 166 LLLFSSATDAAIRVWSLQDRSCLAVLTAHYSAVTSLAFSADGHTMLSSGRDKICIIWDLQ 225
Query: 298 SKEMVEELRPEIINQTQTSKTDPPQCLS-LAWSTDGQTLFAGYSDNTIRVWQVS 140
S + + + + + P + +S L + G T+RVW+ +
Sbjct: 226 SCQATRTV--PVFESVEAAVLLPEEPVSQLGVKSPGLYFLTAGDQGTLRVWEAA 277
Score = 44.4 bits (100), Expect = 4e-04
Identities = 34/157 (21%), Positives = 62/157 (39%), Gaps = 12/157 (7%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
G D +++W+ + T G V V F P+ ++ S D ++VW L +
Sbjct: 127 GGCDGAVRVWDIVRHYG-THHFRGSPGVVHLVAFHPDPTRLLLFSSATDAAIRVWSLQDR 185
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDIITALCF- 362
H + ++ S DG S G+D ++WDL + T+ + + A
Sbjct: 186 SCLAVLTAHYSAVTSLAFSADGHTMLSSGRDKICIIWDLQSCQATRTVPVFESVEAAVLL 245
Query: 361 -----------SPNRYWLCAAFGPSIKIWDLESKEMV 284
SP Y+L A ++++W+ S + V
Sbjct: 246 PEEPVSQLGVKSPGLYFLTAGDQGTLRVWEAASGQCV 282
Score = 43.6 bits (98), Expect = 7e-04
Identities = 40/177 (22%), Positives = 74/177 (41%), Gaps = 10/177 (5%)
Frame = -2
Query: 649 GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGS 470
G+S+ V VRF + ++V+ +KV+ L +I H GH+ + + V G
Sbjct: 332 GYSEEVLDVRFLGPEDSHVVVASN-SPCLKVFELQTSACQILH-GHTDIVLALDVFRKGW 389
Query: 469 LCASGGKDMKAMLWDLNDGKHLHTL----DHNDIITALCFS--PNRYWLCAAFGPSIKIW 308
L AS KD +W +N + + H + +C S + + + ++K+W
Sbjct: 390 LFASCAKDQSVRIWRMNKAGQVMCVAQGSGHTHSVGTVCCSRLKESFLVTGSQDCTVKLW 449
Query: 307 DLE----SKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVW 149
L SK + P ++ T + S+A + + + L G D T ++W
Sbjct: 450 PLPKALLSKNTAPDNGPILLQAQTTQRCHDKDINSVAIAPNDKLLATGSQDRTAKLW 506
>BC007620-1|AAH07620.1| 570|Homo sapiens TBL3 protein protein.
Length = 570
Score = 65.3 bits (152), Expect = 2e-10
Identities = 44/150 (29%), Positives = 69/150 (46%), Gaps = 3/150 (2%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
GS+D+T KLW L +C+ GH + CV+FSP + ++ + D T+K+W L +
Sbjct: 259 GSQDRTAKLW-ALPQCQLLGVFSGHRRGLWCVQFSP--MDQVLATASADGTIKLWALQDF 315
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITAL-C 365
GH + V G+ S G D LW + + + + TLD H D + L C
Sbjct: 316 SCLKTFEGHDASVLKVAFVSRGTQLLSSGSDGLVKLWTIKNNECVRTLDAHEDKVWGLHC 375
Query: 364 FSPNRYWLCAAFGPSIKIW-DLESKEMVEE 278
+ + L A + +W D+ E EE
Sbjct: 376 SRLDDHALTGASDSRVILWKDVTEAEQAEE 405
Score = 52.8 bits (121), Expect = 1e-06
Identities = 45/164 (27%), Positives = 69/164 (42%), Gaps = 16/164 (9%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAEC--KYTIQDDG------------HSDWVSCVRFSPNHANPIIVSC 581
GS+D T+KLW K T D+G H ++ V +PN + ++ +
Sbjct: 202 GSQDCTVKLWPLPKALLSKNTAPDNGPILLQAQTTQRCHDKDINSVAIAPN--DKLLATG 259
Query: 580 GWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLH 401
DRT K+W L C+L GH L V SP + A+ D LW L D L
Sbjct: 260 SQDRTAKLWALPQCQLLGVFSGHRRGLWCVQFSPMDQVLATASADGTIKLWALQDFSCLK 319
Query: 400 TLDHND--IITALCFSPNRYWLCAAFGPSIKIWDLESKEMVEEL 275
T + +D ++ S L + +K+W +++ E V L
Sbjct: 320 TFEGHDASVLKVAFVSRGTQLLSSGSDGLVKLWTIKNNECVRTL 363
Score = 43.6 bits (98), Expect = 7e-04
Identities = 40/177 (22%), Positives = 74/177 (41%), Gaps = 10/177 (5%)
Frame = -2
Query: 649 GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGS 470
G+S+ V VRF + ++V+ +KV+ L +I H GH+ + + V G
Sbjct: 94 GYSEEVLDVRFLGPEDSHVVVASN-SPCLKVFELQTSACQILH-GHTDIVLALDVFRKGW 151
Query: 469 LCASGGKDMKAMLWDLNDGKHLHTL----DHNDIITALCFS--PNRYWLCAAFGPSIKIW 308
L AS KD +W +N + + H + +C S + + + ++K+W
Sbjct: 152 LFASCAKDQSVRIWRMNKAGQVMCVAQGSGHTHSVGTVCCSRLKESFLVTGSQDCTVKLW 211
Query: 307 DLE----SKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVW 149
L SK + P ++ T + S+A + + + L G D T ++W
Sbjct: 212 PLPKALLSKNTAPDNGPILLQAQTTQRCHDKDINSVAIAPNDKLLATGSQDRTAKLW 268
>AF400434-1|AAK92483.1| 410|Homo sapiens platelet-activating factor
acetyl hydrolase isoform Ib alpha subunit protein.
Length = 410
Score = 65.3 bits (152), Expect = 2e-10
Identities = 50/206 (24%), Positives = 94/206 (45%), Gaps = 14/206 (6%)
Frame = -2
Query: 715 SRDKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
S D TIK+W+ + + T++ GH+D V + F +H+ ++ SC D T+K+W
Sbjct: 127 SEDATIKVWDYETGDFERTLK--GHTDSVQDISF--DHSGKLLASCSADMTIKLWDFQGF 182
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCF 362
+ GH +++V + P+G S +D +W++ G + T H + + +
Sbjct: 183 ECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMV-- 240
Query: 361 SPNRYWLCAAF---GPSIKIWDLESKEMVEELR--PEIINQTQTSKTDPPQCLSLAWSTD 197
PN+ A ++++W + +KE ELR ++ + +S A ++
Sbjct: 241 RPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSE 300
Query: 196 -------GQTLFAGYSDNTIRVWQVS 140
G L +G D TI++W VS
Sbjct: 301 TKKSGKPGPFLLSGSRDKTIKMWDVS 326
Score = 54.8 bits (126), Expect = 3e-07
Identities = 47/188 (25%), Positives = 83/188 (44%), Gaps = 2/188 (1%)
Frame = -2
Query: 697 KLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHL 518
K W KY + GH V+ V F P + ++VS D T+KVW +
Sbjct: 92 KEWIPRPPEKYALS--GHRSPVTRVIFHPVFS--VMVSASEDATIKVWDYETGDFERTLK 147
Query: 517 GHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCFSPN-RYW 344
GH+ + ++ G L AS DM LWD + + T+ H+ ++++ PN +
Sbjct: 148 GHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHI 207
Query: 343 LCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDN 164
+ A+ +IK+W++++ V+ ++ P Q DG + + +D
Sbjct: 208 VSASRDKTIKMWEVQTGYCVKTFTG---HREWVRMVRPNQ--------DGTLIASCSNDQ 256
Query: 163 TIRVWQVS 140
T+RVW V+
Sbjct: 257 TVRVWVVA 264
Score = 53.2 bits (122), Expect = 9e-07
Identities = 29/99 (29%), Positives = 47/99 (47%), Gaps = 1/99 (1%)
Frame = -2
Query: 718 GSRDKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
GSRDKTIK+W+ + C T+ GH +WV V F + I+SC D+T++VW N
Sbjct: 314 GSRDKTIKMWDVSTGMCLMTLV--GHDNWVRGVLF--HSGGKFILSCADDKTLRVWDYKN 369
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWD 425
+ H ++ ++ +G D +W+
Sbjct: 370 KRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWE 408
Score = 50.0 bits (114), Expect = 8e-06
Identities = 34/158 (21%), Positives = 69/158 (43%), Gaps = 21/158 (13%)
Frame = -2
Query: 715 SRDKTIKLWNTLA-ECKYTIQDDGHSDWVSCVRFSPNHA------------------NPI 593
S D+T+++W ECK +++ H V C+ ++P + P
Sbjct: 253 SNDQTVRVWVVATKECKAELRE--HEHVVECISWAPESSYSSISEATGSETKKSGKPGPF 310
Query: 592 IVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDG 413
++S D+T+K+W ++ + +GH ++ V G S D +WD +
Sbjct: 311 LLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNK 370
Query: 412 KHLHTLD-HNDIITALCFSPNR-YWLCAAFGPSIKIWD 305
+ + TL+ H +T+L F Y + + ++K+W+
Sbjct: 371 RCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWE 408
>AF208837-1|AAL34972.1| 410|Homo sapiens Miller-Dieker
lissencephaly protein protein.
Length = 410
Score = 65.3 bits (152), Expect = 2e-10
Identities = 50/206 (24%), Positives = 94/206 (45%), Gaps = 14/206 (6%)
Frame = -2
Query: 715 SRDKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
S D TIK+W+ + + T++ GH+D V + F +H+ ++ SC D T+K+W
Sbjct: 127 SEDATIKVWDYETGDFERTLK--GHTDSVQDISF--DHSGKLLASCSADMTIKLWDFQGF 182
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCF 362
+ GH +++V + P+G S +D +W++ G + T H + + +
Sbjct: 183 ECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMV-- 240
Query: 361 SPNRYWLCAAF---GPSIKIWDLESKEMVEELR--PEIINQTQTSKTDPPQCLSLAWSTD 197
PN+ A ++++W + +KE ELR ++ + +S A ++
Sbjct: 241 RPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSE 300
Query: 196 -------GQTLFAGYSDNTIRVWQVS 140
G L +G D TI++W VS
Sbjct: 301 TKKSGKPGPFLLSGSRDKTIKMWDVS 326
Score = 54.8 bits (126), Expect = 3e-07
Identities = 47/188 (25%), Positives = 83/188 (44%), Gaps = 2/188 (1%)
Frame = -2
Query: 697 KLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHL 518
K W KY + GH V+ V F P + ++VS D T+KVW +
Sbjct: 92 KEWIPRPPEKYALS--GHRSPVTRVIFHPVFS--VMVSASEDATIKVWDYETGDFERTLK 147
Query: 517 GHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCFSPN-RYW 344
GH+ + ++ G L AS DM LWD + + T+ H+ ++++ PN +
Sbjct: 148 GHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHI 207
Query: 343 LCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDN 164
+ A+ +IK+W++++ V+ ++ P Q DG + + +D
Sbjct: 208 VSASRDKTIKMWEVQTGYCVKTFTG---HREWVRMVRPNQ--------DGTLIASCSNDQ 256
Query: 163 TIRVWQVS 140
T+RVW V+
Sbjct: 257 TVRVWVVA 264
Score = 53.2 bits (122), Expect = 9e-07
Identities = 29/99 (29%), Positives = 47/99 (47%), Gaps = 1/99 (1%)
Frame = -2
Query: 718 GSRDKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
GSRDKTIK+W+ + C T+ GH +WV V F + I+SC D+T++VW N
Sbjct: 314 GSRDKTIKMWDVSTGMCLMTLV--GHDNWVRGVLF--HSGGKFILSCADDKTLRVWDYKN 369
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWD 425
+ H ++ ++ +G D +W+
Sbjct: 370 KRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWE 408
Score = 50.0 bits (114), Expect = 8e-06
Identities = 34/158 (21%), Positives = 69/158 (43%), Gaps = 21/158 (13%)
Frame = -2
Query: 715 SRDKTIKLWNTLA-ECKYTIQDDGHSDWVSCVRFSPNHA------------------NPI 593
S D+T+++W ECK +++ H V C+ ++P + P
Sbjct: 253 SNDQTVRVWVVATKECKAELRE--HEHVVECISWAPESSYSSISEATGSETKKSGKPGPF 310
Query: 592 IVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDG 413
++S D+T+K+W ++ + +GH ++ V G S D +WD +
Sbjct: 311 LLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNK 370
Query: 412 KHLHTLD-HNDIITALCFSPNR-YWLCAAFGPSIKIWD 305
+ + TL+ H +T+L F Y + + ++K+W+
Sbjct: 371 RCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWE 408
>AB209173-1|BAD92410.1| 832|Homo sapiens transducin beta-like 3
variant protein.
Length = 832
Score = 65.3 bits (152), Expect = 2e-10
Identities = 44/150 (29%), Positives = 69/150 (46%), Gaps = 3/150 (2%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
GS+D+T KLW L +C+ GH + CV+FSP + ++ + D T+K+W L +
Sbjct: 521 GSQDRTAKLW-ALPQCQLLGVFSGHRRGLWCVQFSP--MDQVLATASADGTIKLWALQDF 577
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITAL-C 365
GH + V G+ S G D LW + + + + TLD H D + L C
Sbjct: 578 SCLKTFEGHDASVLKVAFVSRGTQLLSSGSDGLVKLWTIKNNECVRTLDAHEDKVWGLHC 637
Query: 364 FSPNRYWLCAAFGPSIKIW-DLESKEMVEE 278
+ + L A + +W D+ E EE
Sbjct: 638 SRLDDHALTGASDSRVILWKDVTEAEQAEE 667
Score = 52.8 bits (121), Expect = 1e-06
Identities = 45/164 (27%), Positives = 69/164 (42%), Gaps = 16/164 (9%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAEC--KYTIQDDG------------HSDWVSCVRFSPNHANPIIVSC 581
GS+D T+KLW K T D+G H ++ V +PN + ++ +
Sbjct: 464 GSQDCTVKLWPLPKALLPKNTAPDNGPILLQAQTTQRCHDKDINSVAIAPN--DKLLATG 521
Query: 580 GWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLH 401
DRT K+W L C+L GH L V SP + A+ D LW L D L
Sbjct: 522 SQDRTAKLWALPQCQLLGVFSGHRRGLWCVQFSPMDQVLATASADGTIKLWALQDFSCLK 581
Query: 400 TLDHND--IITALCFSPNRYWLCAAFGPSIKIWDLESKEMVEEL 275
T + +D ++ S L + +K+W +++ E V L
Sbjct: 582 TFEGHDASVLKVAFVSRGTQLLSSGSDGLVKLWTIKNNECVRTL 625
Score = 47.6 bits (108), Expect = 4e-05
Identities = 41/174 (23%), Positives = 74/174 (42%), Gaps = 5/174 (2%)
Frame = -2
Query: 646 HSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGS- 470
H+ V+ + F P + ++ + G D V+VW + + G G ++ V PD +
Sbjct: 132 HTAPVATMAFDPT--STLLATGGCDGAVRVWDIVRHYGTHHFRGSPGVVHLVAFHPDPTR 189
Query: 469 -LCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALCFSPNRYWLCAAFGPSI-KIWDLE 299
L S D +W L D L L H +T+L FS + + + ++ I IWDL+
Sbjct: 190 LLLFSSATDAAIRVWSLQDRSCLAVLTAHYSAVTSLAFSADGHTMLSSGRDKICIIWDLQ 249
Query: 298 SKEMVEELRPEIINQTQTSKTDPPQCLS-LAWSTDGQTLFAGYSDNTIRVWQVS 140
S + + + + + P + +S L + G T+RVW+ +
Sbjct: 250 SCQATRTV--PVFESVEAAVLLPEEPVSQLGVKSPGLYFLTAGDQGTLRVWEAA 301
Score = 44.4 bits (100), Expect = 4e-04
Identities = 34/157 (21%), Positives = 62/157 (39%), Gaps = 12/157 (7%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
G D +++W+ + T G V V F P+ ++ S D ++VW L +
Sbjct: 151 GGCDGAVRVWDIVRHYG-THHFRGSPGVVHLVAFHPDPTRLLLFSSATDAAIRVWSLQDR 209
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDIITALCF- 362
H + ++ S DG S G+D ++WDL + T+ + + A
Sbjct: 210 SCLAVLTAHYSAVTSLAFSADGHTMLSSGRDKICIIWDLQSCQATRTVPVFESVEAAVLL 269
Query: 361 -----------SPNRYWLCAAFGPSIKIWDLESKEMV 284
SP Y+L A ++++W+ S + V
Sbjct: 270 PEEPVSQLGVKSPGLYFLTAGDQGTLRVWEAASGQCV 306
Score = 43.6 bits (98), Expect = 7e-04
Identities = 41/177 (23%), Positives = 77/177 (43%), Gaps = 10/177 (5%)
Frame = -2
Query: 649 GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGS 470
G+S+ V VRF + ++V+ +KV+ L +I H GH+ + + V G
Sbjct: 356 GYSEEVLDVRFLGPEDSHVVVASN-SPCLKVFELQTSACQILH-GHTDIVLALDVFRKGW 413
Query: 469 LCASGGKDMKAMLWDLNDGKHLHTL----DHNDIITALCFS--PNRYWLCAAFGPSIKIW 308
L AS KD +W +N + + H + +C S + + + ++K+W
Sbjct: 414 LFASCAKDQSVRIWRMNKAGQVMCVAQGSGHTHSVGTVCCSRLKESFLVTGSQDCTVKLW 473
Query: 307 DLESKEMVEELRPE---IINQTQTS-KTDPPQCLSLAWSTDGQTLFAGYSDNTIRVW 149
L + + P+ I+ Q QT+ + S+A + + + L G D T ++W
Sbjct: 474 PLPKALLPKNTAPDNGPILLQAQTTQRCHDKDINSVAIAPNDKLLATGSQDRTAKLW 530
>AK131444-1|BAD18589.1| 472|Homo sapiens protein ( Homo sapiens
cDNA FLJ16579 fis, clone TESTI2049956, weakly similar
to Vegetatible incompatibility protein HET-E-1. ).
Length = 472
Score = 64.1 bits (149), Expect = 5e-10
Identities = 38/149 (25%), Positives = 73/149 (48%), Gaps = 10/149 (6%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQDDGHSDWVS--CVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
S D+ IK+W+ ++ HS+ +S C FS + + + WD+ +K+W++
Sbjct: 249 SLDRCIKIWDVTSQATLLTITKAHSNAISNCCFTFSGH----FLCTSSWDKNLKIWNVHT 304
Query: 541 CKLKINHL------GHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDG-KHLHTLDHND 383
+ + GH G +++ + D S SGG D +WD+ +G + L HND
Sbjct: 305 GEFRNRGACVTLMQGHEGSVSSCHFARDSSFLISGGFDRTVAIWDVAEGYRKLSLKGHND 364
Query: 382 IITALCFSPNRYW-LCAAFGPSIKIWDLE 299
+ + S N+ W L A+ ++++W++E
Sbjct: 365 WVMDVAISNNKKWILSASKDRTMRLWNIE 393
Score = 50.4 bits (115), Expect = 6e-06
Identities = 38/146 (26%), Positives = 67/146 (45%), Gaps = 4/146 (2%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
GS D T+KLW+ + ++D H V S + +++ +D+TV+ W L
Sbjct: 120 GSYDCTVKLWDPVDGS--VVRDFEHRPKAPVVECSITGDSSRVIAASYDKTVRAWDLETG 177
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASG-GKDMKAMLWDLNDGKHLHTL--DHNDIITAL 368
KL + + + ++ + SPDG SG D + D + + + H IT+
Sbjct: 178 KL-LWKVRYDTFIVSCKFSPDGKYVVSGFDVDHGICIMDAENITTVSVIKDHHTRSITSC 236
Query: 367 CFSPNRYWLCA-AFGPSIKIWDLESK 293
CF P+ + + + IKIWD+ S+
Sbjct: 237 CFDPDSQRVASVSLDRCIKIWDVTSQ 262
Score = 48.8 bits (111), Expect = 2e-05
Identities = 44/197 (22%), Positives = 88/197 (44%), Gaps = 5/197 (2%)
Frame = -2
Query: 715 SRDKTIKLWNT-LAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
S DKT++ W+ + + ++ D VSC +FSP+ ++ D + + N
Sbjct: 164 SYDKTVRAWDLETGKLLWKVRYDTFI--VSC-KFSPD-GKYVVSGFDVDHGICIMDAENI 219
Query: 538 K-LKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD--HNDIITAL 368
+ + H+ + + PD AS D +WD+ L T+ H++ I+
Sbjct: 220 TTVSVIKDHHTRSITSCCFDPDSQRVASVSLDRCIKIWDVTSQATLLTITKAHSNAISNC 279
Query: 367 CFSPNRYWLC-AAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQ 191
CF+ + ++LC +++ ++KIW++ + E R + Q + C ++ D
Sbjct: 280 CFTFSGHFLCTSSWDKNLKIWNVHTGEF--RNRGACVTLMQGHEGSVSSC---HFARDSS 334
Query: 190 TLFAGYSDNTIRVWQVS 140
L +G D T+ +W V+
Sbjct: 335 FLISGGFDRTVAIWDVA 351
Score = 48.0 bits (109), Expect = 3e-05
Identities = 30/107 (28%), Positives = 51/107 (47%), Gaps = 7/107 (6%)
Frame = -2
Query: 715 SRDKTIKLWNT-------LAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKV 557
S DK +K+WN C +Q GH VS F+ + + ++S G+DRTV +
Sbjct: 292 SWDKNLKIWNVHTGEFRNRGACVTLMQ--GHEGSVSSCHFARDSS--FLISGGFDRTVAI 347
Query: 556 WHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLND 416
W + K++ GH+ ++ V +S + S KD LW++ +
Sbjct: 348 WDVAEGYRKLSLKGHNDWVMDVAISNNKKWILSASKDRTMRLWNIEE 394
Score = 39.1 bits (87), Expect = 0.016
Identities = 41/177 (23%), Positives = 70/177 (39%), Gaps = 4/177 (2%)
Frame = -2
Query: 649 GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTV--TVSPD 476
GH VS F + ++S +D TVK+W + + + H V +++ D
Sbjct: 100 GHEHAVSTCHFCVDDTK--LLSGSYDCTVKLWDPVDGSV-VRDFEHRPKAPVVECSITGD 156
Query: 475 GSLCASGGKDMKAMLWDLNDGKHLHTLDHNDIITALCFSPNRYWLCAAF--GPSIKIWDL 302
S + D WDL GK L + ++ I + FSP+ ++ + F I I D
Sbjct: 157 SSRVIAASYDKTVRAWDLETGKLLWKVRYDTFIVSCKFSPDGKYVVSGFDVDHGICIMDA 216
Query: 301 ESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQVSISA 131
E+ V ++ + DP D Q + + D I++W V+ A
Sbjct: 217 ENITTVSVIKDHHTRSITSCCFDP----------DSQRVASVSLDRCIKIWDVTSQA 263
>AF106683-1|AAD43036.1| 421|Homo sapiens WSB-1 protein.
Length = 421
Score = 64.1 bits (149), Expect = 5e-10
Identities = 50/193 (25%), Positives = 83/193 (43%), Gaps = 4/193 (2%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK 536
SRDKT+++W+ + GH +WV FSP+ + ++ G + V +W++
Sbjct: 190 SRDKTLRVWDLKDDGNMMKVLRGHQNWVYSCAFSPDSS--MLCPVGASKAVFLWNMDKYT 247
Query: 535 LKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDIITALCFS- 359
+ GH + SPDG+L A+ D + +WD ++G L H F+
Sbjct: 248 MIRKLEGHHHDVVACDFSPDGALLATASYDTRVYIWDPHNGDILMEFGHLFPPPTPIFAG 307
Query: 358 -PNRYWL-CAAFG-PSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQT 188
N W+ +F + + L +MV R + Q + C A+STDG
Sbjct: 308 GANDRWVRSVSFSHDGLHVASLADDKMVRFWRIDEDYPVQVAPLSNGLC--CAFSTDGSV 365
Query: 187 LFAGYSDNTIRVW 149
L AG D ++ W
Sbjct: 366 LAAGTHDGSVYFW 378
Score = 57.2 bits (132), Expect = 6e-08
Identities = 46/197 (23%), Positives = 90/197 (45%), Gaps = 5/197 (2%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
G + IK+W+ K + H++ V + +P+ + I+VS D+T++VW L +
Sbjct: 146 GLNNGRIKIWDVYTG-KLLLNLVDHTEVVRDLTLAPD-GSLILVSASRDKTLRVWDLKDD 203
Query: 538 KLKINHL-GHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALC 365
+ L GH ++ + SPD S+ G LW+++ + L+ H+ + A
Sbjct: 204 GNMMKVLRGHQNWVYSCAFSPDSSMLCPVGASKAVFLWNMDKYTMIRKLEGHHHDVVACD 263
Query: 364 FSPNRYWLC-AAFGPSIKIWDLESKEMVEELRPEIINQTQ--TSKTDPPQCLSLAWSTDG 194
FSP+ L A++ + IWD + +++ E T + S+++S DG
Sbjct: 264 FSPDGALLATASYDTRVYIWDPHNGDILMEFGHLFPPPTPIFAGGANDRWVRSVSFSHDG 323
Query: 193 QTLFAGYSDNTIRVWQV 143
+ + D +R W++
Sbjct: 324 LHVASLADDKMVRFWRI 340
>BC026353-1|AAH26353.1| 677|Homo sapiens WD repeat domain 48
protein.
Length = 677
Score = 63.3 bits (147), Expect = 8e-10
Identities = 49/193 (25%), Positives = 81/193 (41%), Gaps = 3/193 (1%)
Frame = -2
Query: 712 RDKTIKLW--NTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
RD I++W N + Y + H+DWV+ + N ++S D TVKVW+
Sbjct: 50 RDSIIRIWSVNQHKQDPYIASMEHHTDWVNDIVLCCN--GKTLISASSDTTVKVWNAHKG 107
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDIIT-ALCF 362
H Y+ + + D L AS G D + LWD+N L T +N + T +L
Sbjct: 108 FCMSTLRTHKDYVKALAYAKDKELVASAGLDRQIFLWDVNTLTAL-TASNNTVTTSSLSG 166
Query: 361 SPNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLF 182
+ + + A I +++++ P + K +L + DG
Sbjct: 167 NKDSIYSLAMNQLGTIIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLNRDGTQCL 226
Query: 181 AGYSDNTIRVWQV 143
+G SD TIR+W +
Sbjct: 227 SGSSDGTIRLWSL 239
Score = 47.2 bits (107), Expect = 6e-05
Identities = 32/162 (19%), Positives = 70/162 (43%), Gaps = 7/162 (4%)
Frame = -2
Query: 592 IVSCGWDRTVKVWHLTNCK-----LKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLW 428
+ + G D +++W + K + H H+ ++N + + +G S D +W
Sbjct: 45 LFTAGRDSIIRIWSVNQHKQDPYIASMEH--HTDWVNDIVLCCNGKTLISASSDTTVKVW 102
Query: 427 DLNDGKHLHTL-DHNDIITALCFSPNRYWLCAA-FGPSIKIWDLESKEMVEELRPEIINQ 254
+ + G + TL H D + AL ++ ++ + +A I +WD+ + + +
Sbjct: 103 NAHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDRQIFLWDVNTLTALTASNNTVTTS 162
Query: 253 TQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQVSISAR 128
+ + D SLA + G + +G ++ +RVW A+
Sbjct: 163 SLSGNKD--SIYSLAMNQLGTIIVSGSTEKVLRVWDPRTCAK 202
Score = 43.6 bits (98), Expect = 7e-04
Identities = 33/140 (23%), Positives = 63/140 (45%), Gaps = 6/140 (4%)
Frame = -2
Query: 610 NHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAML 431
N IIVS ++ ++VW C + GH+ + + ++ DG+ C SG D L
Sbjct: 177 NQLGTIIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLNRDGTQCLSGSSDGTIRL 236
Query: 430 WDLNDGKHLHTLD-HNDIITALCFSPNRYWLCAAFGPSIKIW--DLESKE---MVEELRP 269
W L + + T H++ + AL + + + + G KI+ DL + + ++ E +
Sbjct: 237 WSLGQQRCIATYRVHDEGVWALQVN-DAFTHVYSGGRDRKIYCTDLRNPDIRVLICEEKA 295
Query: 268 EIINQTQTSKTDPPQCLSLA 209
++ DPP + +A
Sbjct: 296 PVLKMELDRSADPPPAIWVA 315
>AF468833-1|AAL78650.1| 677|Homo sapiens WD repeat endosomal
protein protein.
Length = 677
Score = 63.3 bits (147), Expect = 8e-10
Identities = 49/193 (25%), Positives = 81/193 (41%), Gaps = 3/193 (1%)
Frame = -2
Query: 712 RDKTIKLW--NTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
RD I++W N + Y + H+DWV+ + N ++S D TVKVW+
Sbjct: 50 RDSIIRIWSVNQHKQDPYIASMEHHTDWVNDIVLCCN--GKTLISASSDTTVKVWNAHKG 107
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDIIT-ALCF 362
H Y+ + + D L AS G D + LWD+N L T +N + T +L
Sbjct: 108 FCMSTLRTHKDYVKALAYAKDKELVASAGLDRQIFLWDVNTLTAL-TASNNTVTTSSLSG 166
Query: 361 SPNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLF 182
+ + + A I +++++ P + K +L + DG
Sbjct: 167 NKDSIYSLAMNQLGTIIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLNRDGTQCL 226
Query: 181 AGYSDNTIRVWQV 143
+G SD TIR+W +
Sbjct: 227 SGSSDGTIRLWSL 239
Score = 47.2 bits (107), Expect = 6e-05
Identities = 32/162 (19%), Positives = 70/162 (43%), Gaps = 7/162 (4%)
Frame = -2
Query: 592 IVSCGWDRTVKVWHLTNCK-----LKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLW 428
+ + G D +++W + K + H H+ ++N + + +G S D +W
Sbjct: 45 LFTAGRDSIIRIWSVNQHKQDPYIASMEH--HTDWVNDIVLCCNGKTLISASSDTTVKVW 102
Query: 427 DLNDGKHLHTL-DHNDIITALCFSPNRYWLCAA-FGPSIKIWDLESKEMVEELRPEIINQ 254
+ + G + TL H D + AL ++ ++ + +A I +WD+ + + +
Sbjct: 103 NAHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDRQIFLWDVNTLTALTASNNTVTTS 162
Query: 253 TQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQVSISAR 128
+ + D SLA + G + +G ++ +RVW A+
Sbjct: 163 SLSGNKD--SIYSLAMNQLGTIIVSGSTEKVLRVWDPRTCAK 202
Score = 43.6 bits (98), Expect = 7e-04
Identities = 33/140 (23%), Positives = 63/140 (45%), Gaps = 6/140 (4%)
Frame = -2
Query: 610 NHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAML 431
N IIVS ++ ++VW C + GH+ + + ++ DG+ C SG D L
Sbjct: 177 NQLGTIIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLNRDGTQCLSGSSDGTIRL 236
Query: 430 WDLNDGKHLHTLD-HNDIITALCFSPNRYWLCAAFGPSIKIW--DLESKE---MVEELRP 269
W L + + T H++ + AL + + + + G KI+ DL + + ++ E +
Sbjct: 237 WSLGQQRCIATYRVHDEGVWALQVN-DAFTHVYSGGRDRKIYCTDLRNPDIRVLICEEKA 295
Query: 268 EIINQTQTSKTDPPQCLSLA 209
++ DPP + +A
Sbjct: 296 PVLKMELDRSADPPPAIWVA 315
>AB040882-1|BAA95973.2| 680|Homo sapiens KIAA1449 protein protein.
Length = 680
Score = 63.3 bits (147), Expect = 8e-10
Identities = 49/193 (25%), Positives = 81/193 (41%), Gaps = 3/193 (1%)
Frame = -2
Query: 712 RDKTIKLW--NTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
RD I++W N + Y + H+DWV+ + N ++S D TVKVW+
Sbjct: 53 RDSIIRIWSVNQHKQDPYIASMEHHTDWVNDIVLCCN--GKTLISASSDTTVKVWNAHKG 110
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDIIT-ALCF 362
H Y+ + + D L AS G D + LWD+N L T +N + T +L
Sbjct: 111 FCMSTLRTHKDYVKALAYAKDKELVASAGLDRQIFLWDVNTLTAL-TASNNTVTTSSLSG 169
Query: 361 SPNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLF 182
+ + + A I +++++ P + K +L + DG
Sbjct: 170 NKDSIYSLAMNQLGTIIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLNRDGTQCL 229
Query: 181 AGYSDNTIRVWQV 143
+G SD TIR+W +
Sbjct: 230 SGSSDGTIRLWSL 242
Score = 47.2 bits (107), Expect = 6e-05
Identities = 32/162 (19%), Positives = 70/162 (43%), Gaps = 7/162 (4%)
Frame = -2
Query: 592 IVSCGWDRTVKVWHLTNCK-----LKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLW 428
+ + G D +++W + K + H H+ ++N + + +G S D +W
Sbjct: 48 LFTAGRDSIIRIWSVNQHKQDPYIASMEH--HTDWVNDIVLCCNGKTLISASSDTTVKVW 105
Query: 427 DLNDGKHLHTL-DHNDIITALCFSPNRYWLCAA-FGPSIKIWDLESKEMVEELRPEIINQ 254
+ + G + TL H D + AL ++ ++ + +A I +WD+ + + +
Sbjct: 106 NAHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDRQIFLWDVNTLTALTASNNTVTTS 165
Query: 253 TQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQVSISAR 128
+ + D SLA + G + +G ++ +RVW A+
Sbjct: 166 SLSGNKD--SIYSLAMNQLGTIIVSGSTEKVLRVWDPRTCAK 205
Score = 43.6 bits (98), Expect = 7e-04
Identities = 33/140 (23%), Positives = 63/140 (45%), Gaps = 6/140 (4%)
Frame = -2
Query: 610 NHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAML 431
N IIVS ++ ++VW C + GH+ + + ++ DG+ C SG D L
Sbjct: 180 NQLGTIIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLNRDGTQCLSGSSDGTIRL 239
Query: 430 WDLNDGKHLHTLD-HNDIITALCFSPNRYWLCAAFGPSIKIW--DLESKE---MVEELRP 269
W L + + T H++ + AL + + + + G KI+ DL + + ++ E +
Sbjct: 240 WSLGQQRCIATYRVHDEGVWALQVN-DAFTHVYSGGRDRKIYCTDLRNPDIRVLICEEKA 298
Query: 268 EIINQTQTSKTDPPQCLSLA 209
++ DPP + +A
Sbjct: 299 PVLKMELDRSADPPPAIWVA 318
>AK222576-1|BAD96296.1| 421|Homo sapiens WD SOCS-box protein 1
isoform 1 variant protein.
Length = 421
Score = 62.9 bits (146), Expect = 1e-09
Identities = 50/193 (25%), Positives = 83/193 (43%), Gaps = 4/193 (2%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK 536
SRDKT+++W+ + GH +WV FSP+ + ++ S G + V +W++
Sbjct: 190 SRDKTLRVWDLKDDGNMMKVLRGHQNWVYSCAFSPDSS--MLCSVGASKAVFLWNMDKYT 247
Query: 535 LKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDIITALCFS- 359
+ G + SPDG+L A+ D + +WD ++G L H F+
Sbjct: 248 MIRKLEGRHHDVVACDFSPDGALLATASYDTRVYIWDPHNGDILMEFGHLFPPPTPIFAG 307
Query: 358 -PNRYWL-CAAFG-PSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQT 188
N W+ +F + + L +MV R + Q + C A+STDG
Sbjct: 308 GANDRWVRSVSFSHDGLHVASLADDKMVRFWRIDEDYPVQVAPLSNGLC--CAFSTDGSV 365
Query: 187 LFAGYSDNTIRVW 149
L AG D ++ W
Sbjct: 366 LAAGTHDGSVYFW 378
Score = 61.7 bits (143), Expect = 3e-09
Identities = 49/198 (24%), Positives = 94/198 (47%), Gaps = 6/198 (3%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
G + IK+W+ K + H++ V + F+P+ + I+VS D+T++VW L +
Sbjct: 146 GLNNGRIKIWDVYTG-KLLLNLVDHTEVVRDLTFAPD-GSLILVSASRDKTLRVWDLKDD 203
Query: 538 KLKINHL-GHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD--HNDIITAL 368
+ L GH ++ + SPD S+ S G LW+++ + L+ H+D++ A
Sbjct: 204 GNMMKVLRGHQNWVYSCAFSPDSSMLCSVGASKAVFLWNMDKYTMIRKLEGRHHDVV-AC 262
Query: 367 CFSPNRYWLC-AAFGPSIKIWDLESKEMVEELRPEIINQTQ--TSKTDPPQCLSLAWSTD 197
FSP+ L A++ + IWD + +++ E T + S+++S D
Sbjct: 263 DFSPDGALLATASYDTRVYIWDPHNGDILMEFGHLFPPPTPIFAGGANDRWVRSVSFSHD 322
Query: 196 GQTLFAGYSDNTIRVWQV 143
G + + D +R W++
Sbjct: 323 GLHVASLADDKMVRFWRI 340
>BC026213-1|AAH26213.1| 529|Homo sapiens F-box and WD repeat domain
containing 11 protein.
Length = 529
Score = 62.1 bits (144), Expect = 2e-09
Identities = 41/143 (28%), Positives = 68/143 (47%), Gaps = 3/143 (2%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQDD--GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
S+D++I +W+ + T++ GH V+ V F + IVS DRT+KVW +
Sbjct: 324 SKDRSIAVWDMASATDITLRRVLVGHRAAVNVVDFDDKY----IVSASGDRTIKVWSTST 379
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALC 365
C+ GH + + L SG D LWD+ G L L+ H +++ +
Sbjct: 380 CEFVRTLNGHKRGIACLQYRD--RLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIR 437
Query: 364 FSPNRYWLCAAFGPSIKIWDLES 296
F N+ + A+ IK+WDL++
Sbjct: 438 FD-NKRIVSGAYDGKIKVWDLQA 459
Score = 52.4 bits (120), Expect = 2e-06
Identities = 39/152 (25%), Positives = 70/152 (46%), Gaps = 1/152 (0%)
Frame = -2
Query: 592 IVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDG 413
I+S D ++K+W T+ + GH+G + + + D + +G D +WD+N G
Sbjct: 240 IISGLRDNSIKIWDKTSLECLKVLTGHTG--SVLCLQYDERVIVTGSSDSTVRVWDVNTG 297
Query: 412 KHLHTL-DHNDIITALCFSPNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKT 236
+ L+TL HN+ + L FS N + + SI +WD+ S + R + ++ +
Sbjct: 298 EVLNTLIHHNEAVLHLRFS-NGLMVTCSKDRSIAVWDMASATDITLRRVLVGHRAAVNVV 356
Query: 235 DPPQCLSLAWSTDGQTLFAGYSDNTIRVWQVS 140
D D + + + D TI+VW S
Sbjct: 357 D----------FDDKYIVSASGDRTIKVWSTS 378
Score = 50.0 bits (114), Expect = 8e-06
Identities = 40/145 (27%), Positives = 74/145 (51%), Gaps = 5/145 (3%)
Frame = -2
Query: 718 GSRDKTIKLWNT-LAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHL-- 548
GS D T+++W+ E T+ H++ V +RFS N ++V+C DR++ VW +
Sbjct: 283 GSSDSTVRVWDVNTGEVLNTLIH--HNEAVLHLRFS----NGLMVTCSKDRSIAVWDMAS 336
Query: 547 -TNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIIT 374
T+ L+ +GH +N V + ASG + +K +W + + + TL+ H I
Sbjct: 337 ATDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIK--VWSTSTCEFVRTLNGHKRGIA 394
Query: 373 ALCFSPNRYWLCAAFGPSIKIWDLE 299
L + +R + + +I++WD+E
Sbjct: 395 CLQYR-DRLVVSGSSDNTIRLWDIE 418
>AF176022-1|AAF04528.1| 542|Homo sapiens F-box protein Fbw1b
protein.
Length = 542
Score = 62.1 bits (144), Expect = 2e-09
Identities = 41/143 (28%), Positives = 68/143 (47%), Gaps = 3/143 (2%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQDD--GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
S+D++I +W+ + T++ GH V+ V F + IVS DRT+KVW +
Sbjct: 337 SKDRSIAVWDMASATDITLRRVLVGHRAAVNVVDFDDKY----IVSASGDRTIKVWSTST 392
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALC 365
C+ GH + + L SG D LWD+ G L L+ H +++ +
Sbjct: 393 CEFVRTLNGHKRGIACLQYRD--RLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIR 450
Query: 364 FSPNRYWLCAAFGPSIKIWDLES 296
F N+ + A+ IK+WDL++
Sbjct: 451 FD-NKRIVSGAYDGKIKVWDLQA 472
Score = 52.4 bits (120), Expect = 2e-06
Identities = 39/152 (25%), Positives = 70/152 (46%), Gaps = 1/152 (0%)
Frame = -2
Query: 592 IVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDG 413
I+S D ++K+W T+ + GH+G + + + D + +G D +WD+N G
Sbjct: 253 IISGLRDNSIKIWDKTSLECLKVLTGHTG--SVLCLQYDERVIVTGSSDSTVRVWDVNTG 310
Query: 412 KHLHTL-DHNDIITALCFSPNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKT 236
+ L+TL HN+ + L FS N + + SI +WD+ S + R + ++ +
Sbjct: 311 EVLNTLIHHNEAVLHLRFS-NGLMVTCSKDRSIAVWDMASATDITLRRVLVGHRAAVNVV 369
Query: 235 DPPQCLSLAWSTDGQTLFAGYSDNTIRVWQVS 140
D D + + + D TI+VW S
Sbjct: 370 D----------FDDKYIVSASGDRTIKVWSTS 391
Score = 50.0 bits (114), Expect = 8e-06
Identities = 40/145 (27%), Positives = 74/145 (51%), Gaps = 5/145 (3%)
Frame = -2
Query: 718 GSRDKTIKLWNT-LAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHL-- 548
GS D T+++W+ E T+ H++ V +RFS N ++V+C DR++ VW +
Sbjct: 296 GSSDSTVRVWDVNTGEVLNTLIH--HNEAVLHLRFS----NGLMVTCSKDRSIAVWDMAS 349
Query: 547 -TNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIIT 374
T+ L+ +GH +N V + ASG + +K +W + + + TL+ H I
Sbjct: 350 ATDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIK--VWSTSTCEFVRTLNGHKRGIA 407
Query: 373 ALCFSPNRYWLCAAFGPSIKIWDLE 299
L + +R + + +I++WD+E
Sbjct: 408 CLQYR-DRLVVSGSSDNTIRLWDIE 431
>AB033281-1|BAA92331.1| 542|Homo sapiens F-box and WD-repeats
protein beta-TRCP2 isoform C protein.
Length = 542
Score = 62.1 bits (144), Expect = 2e-09
Identities = 41/143 (28%), Positives = 68/143 (47%), Gaps = 3/143 (2%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQDD--GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
S+D++I +W+ + T++ GH V+ V F + IVS DRT+KVW +
Sbjct: 337 SKDRSIAVWDMASATDITLRRVLVGHRAAVNVVDFDDKY----IVSASGDRTIKVWSTST 392
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALC 365
C+ GH + + L SG D LWD+ G L L+ H +++ +
Sbjct: 393 CEFVRTLNGHKRGIACLQYRD--RLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIR 450
Query: 364 FSPNRYWLCAAFGPSIKIWDLES 296
F N+ + A+ IK+WDL++
Sbjct: 451 FD-NKRIVSGAYDGKIKVWDLQA 472
Score = 52.4 bits (120), Expect = 2e-06
Identities = 39/152 (25%), Positives = 70/152 (46%), Gaps = 1/152 (0%)
Frame = -2
Query: 592 IVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDG 413
I+S D ++K+W T+ + GH+G + + + D + +G D +WD+N G
Sbjct: 253 IISGLRDNSIKIWDKTSLECLKVLTGHTG--SVLCLQYDERVIVTGSSDSTVRVWDVNTG 310
Query: 412 KHLHTL-DHNDIITALCFSPNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKT 236
+ L+TL HN+ + L FS N + + SI +WD+ S + R + ++ +
Sbjct: 311 EVLNTLIHHNEAVLHLRFS-NGLMVTCSKDRSIAVWDMASATDITLRRVLVGHRAAVNVV 369
Query: 235 DPPQCLSLAWSTDGQTLFAGYSDNTIRVWQVS 140
D D + + + D TI+VW S
Sbjct: 370 D----------FDDKYIVSASGDRTIKVWSTS 391
Score = 50.0 bits (114), Expect = 8e-06
Identities = 40/145 (27%), Positives = 74/145 (51%), Gaps = 5/145 (3%)
Frame = -2
Query: 718 GSRDKTIKLWNT-LAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHL-- 548
GS D T+++W+ E T+ H++ V +RFS N ++V+C DR++ VW +
Sbjct: 296 GSSDSTVRVWDVNTGEVLNTLIH--HNEAVLHLRFS----NGLMVTCSKDRSIAVWDMAS 349
Query: 547 -TNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIIT 374
T+ L+ +GH +N V + ASG + +K +W + + + TL+ H I
Sbjct: 350 ATDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIK--VWSTSTCEFVRTLNGHKRGIA 407
Query: 373 ALCFSPNRYWLCAAFGPSIKIWDLE 299
L + +R + + +I++WD+E
Sbjct: 408 CLQYR-DRLVVSGSSDNTIRLWDIE 431
>AB033280-1|BAA92330.1| 529|Homo sapiens F-box and WD-repeats
protein beta-TRCP2 isoform B protein.
Length = 529
Score = 62.1 bits (144), Expect = 2e-09
Identities = 41/143 (28%), Positives = 68/143 (47%), Gaps = 3/143 (2%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQDD--GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
S+D++I +W+ + T++ GH V+ V F + IVS DRT+KVW +
Sbjct: 324 SKDRSIAVWDMASATDITLRRVLVGHRAAVNVVDFDDKY----IVSASGDRTIKVWSTST 379
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALC 365
C+ GH + + L SG D LWD+ G L L+ H +++ +
Sbjct: 380 CEFVRTLNGHKRGIACLQYRD--RLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIR 437
Query: 364 FSPNRYWLCAAFGPSIKIWDLES 296
F N+ + A+ IK+WDL++
Sbjct: 438 FD-NKRIVSGAYDGKIKVWDLQA 459
Score = 52.4 bits (120), Expect = 2e-06
Identities = 39/152 (25%), Positives = 70/152 (46%), Gaps = 1/152 (0%)
Frame = -2
Query: 592 IVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDG 413
I+S D ++K+W T+ + GH+G + + + D + +G D +WD+N G
Sbjct: 240 IISGLRDNSIKIWDKTSLECLKVLTGHTG--SVLCLQYDERVIVTGSSDSTVRVWDVNTG 297
Query: 412 KHLHTL-DHNDIITALCFSPNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKT 236
+ L+TL HN+ + L FS N + + SI +WD+ S + R + ++ +
Sbjct: 298 EVLNTLIHHNEAVLHLRFS-NGLMVTCSKDRSIAVWDMASATDITLRRVLVGHRAAVNVV 356
Query: 235 DPPQCLSLAWSTDGQTLFAGYSDNTIRVWQVS 140
D D + + + D TI+VW S
Sbjct: 357 D----------FDDKYIVSASGDRTIKVWSTS 378
Score = 50.0 bits (114), Expect = 8e-06
Identities = 40/145 (27%), Positives = 74/145 (51%), Gaps = 5/145 (3%)
Frame = -2
Query: 718 GSRDKTIKLWNT-LAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHL-- 548
GS D T+++W+ E T+ H++ V +RFS N ++V+C DR++ VW +
Sbjct: 283 GSSDSTVRVWDVNTGEVLNTLIH--HNEAVLHLRFS----NGLMVTCSKDRSIAVWDMAS 336
Query: 547 -TNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIIT 374
T+ L+ +GH +N V + ASG + +K +W + + + TL+ H I
Sbjct: 337 ATDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIK--VWSTSTCEFVRTLNGHKRGIA 394
Query: 373 ALCFSPNRYWLCAAFGPSIKIWDLE 299
L + +R + + +I++WD+E
Sbjct: 395 CLQYR-DRLVVSGSSDNTIRLWDIE 418
>AB033279-1|BAA92329.1| 508|Homo sapiens F-box and WD-repeats
protein beta-TRCP2 isoform A protein.
Length = 508
Score = 62.1 bits (144), Expect = 2e-09
Identities = 41/143 (28%), Positives = 68/143 (47%), Gaps = 3/143 (2%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQDD--GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
S+D++I +W+ + T++ GH V+ V F + IVS DRT+KVW +
Sbjct: 303 SKDRSIAVWDMASATDITLRRVLVGHRAAVNVVDFDDKY----IVSASGDRTIKVWSTST 358
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALC 365
C+ GH + + L SG D LWD+ G L L+ H +++ +
Sbjct: 359 CEFVRTLNGHKRGIACLQYRD--RLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIR 416
Query: 364 FSPNRYWLCAAFGPSIKIWDLES 296
F N+ + A+ IK+WDL++
Sbjct: 417 FD-NKRIVSGAYDGKIKVWDLQA 438
Score = 52.4 bits (120), Expect = 2e-06
Identities = 39/152 (25%), Positives = 70/152 (46%), Gaps = 1/152 (0%)
Frame = -2
Query: 592 IVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDG 413
I+S D ++K+W T+ + GH+G + + + D + +G D +WD+N G
Sbjct: 219 IISGLRDNSIKIWDKTSLECLKVLTGHTG--SVLCLQYDERVIVTGSSDSTVRVWDVNTG 276
Query: 412 KHLHTL-DHNDIITALCFSPNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKT 236
+ L+TL HN+ + L FS N + + SI +WD+ S + R + ++ +
Sbjct: 277 EVLNTLIHHNEAVLHLRFS-NGLMVTCSKDRSIAVWDMASATDITLRRVLVGHRAAVNVV 335
Query: 235 DPPQCLSLAWSTDGQTLFAGYSDNTIRVWQVS 140
D D + + + D TI+VW S
Sbjct: 336 D----------FDDKYIVSASGDRTIKVWSTS 357
Score = 50.0 bits (114), Expect = 8e-06
Identities = 40/145 (27%), Positives = 74/145 (51%), Gaps = 5/145 (3%)
Frame = -2
Query: 718 GSRDKTIKLWNT-LAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHL-- 548
GS D T+++W+ E T+ H++ V +RFS N ++V+C DR++ VW +
Sbjct: 262 GSSDSTVRVWDVNTGEVLNTLIH--HNEAVLHLRFS----NGLMVTCSKDRSIAVWDMAS 315
Query: 547 -TNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIIT 374
T+ L+ +GH +N V + ASG + +K +W + + + TL+ H I
Sbjct: 316 ATDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIK--VWSTSTCEFVRTLNGHKRGIA 373
Query: 373 ALCFSPNRYWLCAAFGPSIKIWDLE 299
L + +R + + +I++WD+E
Sbjct: 374 CLQYR-DRLVVSGSSDNTIRLWDIE 397
>AB014596-1|BAA31671.1| 550|Homo sapiens KIAA0696 protein protein.
Length = 550
Score = 62.1 bits (144), Expect = 2e-09
Identities = 41/143 (28%), Positives = 68/143 (47%), Gaps = 3/143 (2%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQDD--GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
S+D++I +W+ + T++ GH V+ V F + IVS DRT+KVW +
Sbjct: 345 SKDRSIAVWDMASATDITLRRVLVGHRAAVNVVDFDDKY----IVSASGDRTIKVWSTST 400
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALC 365
C+ GH + + L SG D LWD+ G L L+ H +++ +
Sbjct: 401 CEFVRTLNGHKRGIACLQYRD--RLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIR 458
Query: 364 FSPNRYWLCAAFGPSIKIWDLES 296
F N+ + A+ IK+WDL++
Sbjct: 459 FD-NKRIVSGAYDGKIKVWDLQA 480
Score = 52.4 bits (120), Expect = 2e-06
Identities = 39/152 (25%), Positives = 70/152 (46%), Gaps = 1/152 (0%)
Frame = -2
Query: 592 IVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDG 413
I+S D ++K+W T+ + GH+G + + + D + +G D +WD+N G
Sbjct: 261 IISGLRDNSIKIWDKTSLECLKVLTGHTG--SVLCLQYDERVIVTGSSDSTVRVWDVNTG 318
Query: 412 KHLHTL-DHNDIITALCFSPNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKT 236
+ L+TL HN+ + L FS N + + SI +WD+ S + R + ++ +
Sbjct: 319 EVLNTLIHHNEAVLHLRFS-NGLMVTCSKDRSIAVWDMASATDITLRRVLVGHRAAVNVV 377
Query: 235 DPPQCLSLAWSTDGQTLFAGYSDNTIRVWQVS 140
D D + + + D TI+VW S
Sbjct: 378 D----------FDDKYIVSASGDRTIKVWSTS 399
Score = 50.0 bits (114), Expect = 8e-06
Identities = 40/145 (27%), Positives = 74/145 (51%), Gaps = 5/145 (3%)
Frame = -2
Query: 718 GSRDKTIKLWNT-LAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHL-- 548
GS D T+++W+ E T+ H++ V +RFS N ++V+C DR++ VW +
Sbjct: 304 GSSDSTVRVWDVNTGEVLNTLIH--HNEAVLHLRFS----NGLMVTCSKDRSIAVWDMAS 357
Query: 547 -TNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIIT 374
T+ L+ +GH +N V + ASG + +K +W + + + TL+ H I
Sbjct: 358 ATDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIK--VWSTSTCEFVRTLNGHKRGIA 415
Query: 373 ALCFSPNRYWLCAAFGPSIKIWDLE 299
L + +R + + +I++WD+E
Sbjct: 416 CLQYR-DRLVVSGSSDNTIRLWDIE 439
>Y14153-1|CAA74572.1| 569|Homo sapiens beta-transducin repeats
containing protein protein.
Length = 569
Score = 61.7 bits (143), Expect = 3e-09
Identities = 41/141 (29%), Positives = 67/141 (47%), Gaps = 3/141 (2%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQDD--GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
S+D++I +W+ + T++ GH V+ V F + IVS DRT+KVW+ +
Sbjct: 364 SKDRSIAVWDMASPTDITLRRVLVGHRAAVNVVDFDDKY----IVSASGDRTIKVWNTST 419
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALC 365
C+ GH + + L SG D LWD+ G L L+ H +++ +
Sbjct: 420 CEFVRTLNGHKRGIACLQYRD--RLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIR 477
Query: 364 FSPNRYWLCAAFGPSIKIWDL 302
F N+ + A+ IK+WDL
Sbjct: 478 FD-NKRIVSGAYDGKIKVWDL 497
Score = 51.2 bits (117), Expect = 4e-06
Identities = 39/152 (25%), Positives = 68/152 (44%), Gaps = 1/152 (0%)
Frame = -2
Query: 592 IVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDG 413
IVS D T+K+W + K GH+G + + + D + +G D +WD+N G
Sbjct: 280 IVSGLRDNTIKIWDKNTLECKRILTGHTG--SVLCLQYDERVIITGSSDSTVRVWDVNTG 337
Query: 412 KHLHTLDHN-DIITALCFSPNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKT 236
+ L+TL H+ + + L F+ C+ SI +WD+ S + R + ++ +
Sbjct: 338 EMLNTLIHHCEAVLHLRFNNGMMVTCSK-DRSIAVWDMASPTDITLRRVLVGHRAAVNVV 396
Query: 235 DPPQCLSLAWSTDGQTLFAGYSDNTIRVWQVS 140
D D + + + D TI+VW S
Sbjct: 397 D----------FDDKYIVSASGDRTIKVWNTS 418
Score = 51.2 bits (117), Expect = 4e-06
Identities = 51/202 (25%), Positives = 90/202 (44%), Gaps = 6/202 (2%)
Frame = -2
Query: 718 GSRDKTIKLW--NTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 545
G RD TIK+W NTL ECK + GH+ V C+++ +I++ D TV+VW +
Sbjct: 283 GLRDNTIKIWDKNTL-ECKRIL--TGHTGSVLCLQYDER----VIITGSSDSTVRVWDVN 335
Query: 544 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLH----TLDHNDII 377
++ +N L H + + + + + KD +WD+ + + H +
Sbjct: 336 TGEM-LNTLIHHCEA-VLHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRRVLVGHRAAV 393
Query: 376 TALCFSPNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTD 197
+ F ++Y + A+ +IK+W+ + E V +T CL
Sbjct: 394 NVVDFD-DKYIVSASGDRTIKVWNTSTCEFV---------RTLNGHKRGIACLQYR---- 439
Query: 196 GQTLFAGYSDNTIRVWQVSISA 131
+ + +G SDNTIR+W + A
Sbjct: 440 DRLVVSGSSDNTIRLWDIECGA 461
>BC027994-1|AAH27994.1| 605|Homo sapiens beta-transducin repeat
containing protein.
Length = 605
Score = 61.7 bits (143), Expect = 3e-09
Identities = 41/141 (29%), Positives = 67/141 (47%), Gaps = 3/141 (2%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQDD--GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
S+D++I +W+ + T++ GH V+ V F + IVS DRT+KVW+ +
Sbjct: 400 SKDRSIAVWDMASPTDITLRRVLVGHRAAVNVVDFDDKY----IVSASGDRTIKVWNTST 455
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALC 365
C+ GH + + L SG D LWD+ G L L+ H +++ +
Sbjct: 456 CEFVRTLNGHKRGIACLQYRD--RLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIR 513
Query: 364 FSPNRYWLCAAFGPSIKIWDL 302
F N+ + A+ IK+WDL
Sbjct: 514 FD-NKRIVSGAYDGKIKVWDL 533
Score = 51.2 bits (117), Expect = 4e-06
Identities = 39/152 (25%), Positives = 68/152 (44%), Gaps = 1/152 (0%)
Frame = -2
Query: 592 IVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDG 413
IVS D T+K+W + K GH+G + + + D + +G D +WD+N G
Sbjct: 316 IVSGLRDNTIKIWDKNTLECKRILTGHTG--SVLCLQYDERVIITGSSDSTVRVWDVNTG 373
Query: 412 KHLHTLDHN-DIITALCFSPNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKT 236
+ L+TL H+ + + L F+ C+ SI +WD+ S + R + ++ +
Sbjct: 374 EMLNTLIHHCEAVLHLRFNNGMMVTCSK-DRSIAVWDMASPTDITLRRVLVGHRAAVNVV 432
Query: 235 DPPQCLSLAWSTDGQTLFAGYSDNTIRVWQVS 140
D D + + + D TI+VW S
Sbjct: 433 D----------FDDKYIVSASGDRTIKVWNTS 454
Score = 51.2 bits (117), Expect = 4e-06
Identities = 51/202 (25%), Positives = 90/202 (44%), Gaps = 6/202 (2%)
Frame = -2
Query: 718 GSRDKTIKLW--NTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 545
G RD TIK+W NTL ECK + GH+ V C+++ +I++ D TV+VW +
Sbjct: 319 GLRDNTIKIWDKNTL-ECKRIL--TGHTGSVLCLQYDER----VIITGSSDSTVRVWDVN 371
Query: 544 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLH----TLDHNDII 377
++ +N L H + + + + + KD +WD+ + + H +
Sbjct: 372 TGEM-LNTLIHHCEA-VLHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRRVLVGHRAAV 429
Query: 376 TALCFSPNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTD 197
+ F ++Y + A+ +IK+W+ + E V +T CL
Sbjct: 430 NVVDFD-DKYIVSASGDRTIKVWNTSTCEFV---------RTLNGHKRGIACLQYR---- 475
Query: 196 GQTLFAGYSDNTIRVWQVSISA 131
+ + +G SDNTIR+W + A
Sbjct: 476 DRLVVSGSSDNTIRLWDIECGA 497
>AL627424-18|CAI41043.1| 569|Homo sapiens beta-transducin repeat
containing protein.
Length = 569
Score = 61.7 bits (143), Expect = 3e-09
Identities = 41/141 (29%), Positives = 67/141 (47%), Gaps = 3/141 (2%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQDD--GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
S+D++I +W+ + T++ GH V+ V F + IVS DRT+KVW+ +
Sbjct: 364 SKDRSIAVWDMASPTDITLRRVLVGHRAAVNVVDFDDKY----IVSASGDRTIKVWNTST 419
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALC 365
C+ GH + + L SG D LWD+ G L L+ H +++ +
Sbjct: 420 CEFVRTLNGHKRGIACLQYRD--RLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIR 477
Query: 364 FSPNRYWLCAAFGPSIKIWDL 302
F N+ + A+ IK+WDL
Sbjct: 478 FD-NKRIVSGAYDGKIKVWDL 497
Score = 51.2 bits (117), Expect = 4e-06
Identities = 39/152 (25%), Positives = 68/152 (44%), Gaps = 1/152 (0%)
Frame = -2
Query: 592 IVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDG 413
IVS D T+K+W + K GH+G + + + D + +G D +WD+N G
Sbjct: 280 IVSGLRDNTIKIWDKNTLECKRILTGHTG--SVLCLQYDERVIITGSSDSTVRVWDVNTG 337
Query: 412 KHLHTLDHN-DIITALCFSPNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKT 236
+ L+TL H+ + + L F+ C+ SI +WD+ S + R + ++ +
Sbjct: 338 EMLNTLIHHCEAVLHLRFNNGMMVTCSK-DRSIAVWDMASPTDITLRRVLVGHRAAVNVV 396
Query: 235 DPPQCLSLAWSTDGQTLFAGYSDNTIRVWQVS 140
D D + + + D TI+VW S
Sbjct: 397 D----------FDDKYIVSASGDRTIKVWNTS 418
Score = 51.2 bits (117), Expect = 4e-06
Identities = 51/202 (25%), Positives = 90/202 (44%), Gaps = 6/202 (2%)
Frame = -2
Query: 718 GSRDKTIKLW--NTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 545
G RD TIK+W NTL ECK + GH+ V C+++ +I++ D TV+VW +
Sbjct: 283 GLRDNTIKIWDKNTL-ECKRIL--TGHTGSVLCLQYDER----VIITGSSDSTVRVWDVN 335
Query: 544 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLH----TLDHNDII 377
++ +N L H + + + + + KD +WD+ + + H +
Sbjct: 336 TGEM-LNTLIHHCEA-VLHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRRVLVGHRAAV 393
Query: 376 TALCFSPNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTD 197
+ F ++Y + A+ +IK+W+ + E V +T CL
Sbjct: 394 NVVDFD-DKYIVSASGDRTIKVWNTSTCEFV---------RTLNGHKRGIACLQYR---- 439
Query: 196 GQTLFAGYSDNTIRVWQVSISA 131
+ + +G SDNTIR+W + A
Sbjct: 440 DRLVVSGSSDNTIRLWDIECGA 461
>AL627424-17|CAI41042.1| 605|Homo sapiens beta-transducin repeat
containing protein.
Length = 605
Score = 61.7 bits (143), Expect = 3e-09
Identities = 41/141 (29%), Positives = 67/141 (47%), Gaps = 3/141 (2%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQDD--GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
S+D++I +W+ + T++ GH V+ V F + IVS DRT+KVW+ +
Sbjct: 400 SKDRSIAVWDMASPTDITLRRVLVGHRAAVNVVDFDDKY----IVSASGDRTIKVWNTST 455
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALC 365
C+ GH + + L SG D LWD+ G L L+ H +++ +
Sbjct: 456 CEFVRTLNGHKRGIACLQYRD--RLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIR 513
Query: 364 FSPNRYWLCAAFGPSIKIWDL 302
F N+ + A+ IK+WDL
Sbjct: 514 FD-NKRIVSGAYDGKIKVWDL 533
Score = 51.2 bits (117), Expect = 4e-06
Identities = 39/152 (25%), Positives = 68/152 (44%), Gaps = 1/152 (0%)
Frame = -2
Query: 592 IVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDG 413
IVS D T+K+W + K GH+G + + + D + +G D +WD+N G
Sbjct: 316 IVSGLRDNTIKIWDKNTLECKRILTGHTG--SVLCLQYDERVIITGSSDSTVRVWDVNTG 373
Query: 412 KHLHTLDHN-DIITALCFSPNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKT 236
+ L+TL H+ + + L F+ C+ SI +WD+ S + R + ++ +
Sbjct: 374 EMLNTLIHHCEAVLHLRFNNGMMVTCSK-DRSIAVWDMASPTDITLRRVLVGHRAAVNVV 432
Query: 235 DPPQCLSLAWSTDGQTLFAGYSDNTIRVWQVS 140
D D + + + D TI+VW S
Sbjct: 433 D----------FDDKYIVSASGDRTIKVWNTS 454
Score = 51.2 bits (117), Expect = 4e-06
Identities = 51/202 (25%), Positives = 90/202 (44%), Gaps = 6/202 (2%)
Frame = -2
Query: 718 GSRDKTIKLW--NTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 545
G RD TIK+W NTL ECK + GH+ V C+++ +I++ D TV+VW +
Sbjct: 319 GLRDNTIKIWDKNTL-ECKRIL--TGHTGSVLCLQYDER----VIITGSSDSTVRVWDVN 371
Query: 544 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLH----TLDHNDII 377
++ +N L H + + + + + KD +WD+ + + H +
Sbjct: 372 TGEM-LNTLIHHCEA-VLHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRRVLVGHRAAV 429
Query: 376 TALCFSPNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTD 197
+ F ++Y + A+ +IK+W+ + E V +T CL
Sbjct: 430 NVVDFD-DKYIVSASGDRTIKVWNTSTCEFV---------RTLNGHKRGIACLQYR---- 475
Query: 196 GQTLFAGYSDNTIRVWQVSISA 131
+ + +G SDNTIR+W + A
Sbjct: 476 DRLVVSGSSDNTIRLWDIECGA 497
>AL445463-3|CAI12964.1| 569|Homo sapiens beta-transducin repeat
containing protein.
Length = 569
Score = 61.7 bits (143), Expect = 3e-09
Identities = 41/141 (29%), Positives = 67/141 (47%), Gaps = 3/141 (2%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQDD--GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
S+D++I +W+ + T++ GH V+ V F + IVS DRT+KVW+ +
Sbjct: 364 SKDRSIAVWDMASPTDITLRRVLVGHRAAVNVVDFDDKY----IVSASGDRTIKVWNTST 419
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALC 365
C+ GH + + L SG D LWD+ G L L+ H +++ +
Sbjct: 420 CEFVRTLNGHKRGIACLQYRD--RLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIR 477
Query: 364 FSPNRYWLCAAFGPSIKIWDL 302
F N+ + A+ IK+WDL
Sbjct: 478 FD-NKRIVSGAYDGKIKVWDL 497
Score = 51.2 bits (117), Expect = 4e-06
Identities = 39/152 (25%), Positives = 68/152 (44%), Gaps = 1/152 (0%)
Frame = -2
Query: 592 IVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDG 413
IVS D T+K+W + K GH+G + + + D + +G D +WD+N G
Sbjct: 280 IVSGLRDNTIKIWDKNTLECKRILTGHTG--SVLCLQYDERVIITGSSDSTVRVWDVNTG 337
Query: 412 KHLHTLDHN-DIITALCFSPNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKT 236
+ L+TL H+ + + L F+ C+ SI +WD+ S + R + ++ +
Sbjct: 338 EMLNTLIHHCEAVLHLRFNNGMMVTCSK-DRSIAVWDMASPTDITLRRVLVGHRAAVNVV 396
Query: 235 DPPQCLSLAWSTDGQTLFAGYSDNTIRVWQVS 140
D D + + + D TI+VW S
Sbjct: 397 D----------FDDKYIVSASGDRTIKVWNTS 418
Score = 51.2 bits (117), Expect = 4e-06
Identities = 51/202 (25%), Positives = 90/202 (44%), Gaps = 6/202 (2%)
Frame = -2
Query: 718 GSRDKTIKLW--NTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 545
G RD TIK+W NTL ECK + GH+ V C+++ +I++ D TV+VW +
Sbjct: 283 GLRDNTIKIWDKNTL-ECKRIL--TGHTGSVLCLQYDER----VIITGSSDSTVRVWDVN 335
Query: 544 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLH----TLDHNDII 377
++ +N L H + + + + + KD +WD+ + + H +
Sbjct: 336 TGEM-LNTLIHHCEA-VLHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRRVLVGHRAAV 393
Query: 376 TALCFSPNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTD 197
+ F ++Y + A+ +IK+W+ + E V +T CL
Sbjct: 394 NVVDFD-DKYIVSASGDRTIKVWNTSTCEFV---------RTLNGHKRGIACLQYR---- 439
Query: 196 GQTLFAGYSDNTIRVWQVSISA 131
+ + +G SDNTIR+W + A
Sbjct: 440 DRLVVSGSSDNTIRLWDIECGA 461
>AL445463-2|CAI12963.1| 605|Homo sapiens beta-transducin repeat
containing protein.
Length = 605
Score = 61.7 bits (143), Expect = 3e-09
Identities = 41/141 (29%), Positives = 67/141 (47%), Gaps = 3/141 (2%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQDD--GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
S+D++I +W+ + T++ GH V+ V F + IVS DRT+KVW+ +
Sbjct: 400 SKDRSIAVWDMASPTDITLRRVLVGHRAAVNVVDFDDKY----IVSASGDRTIKVWNTST 455
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALC 365
C+ GH + + L SG D LWD+ G L L+ H +++ +
Sbjct: 456 CEFVRTLNGHKRGIACLQYRD--RLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIR 513
Query: 364 FSPNRYWLCAAFGPSIKIWDL 302
F N+ + A+ IK+WDL
Sbjct: 514 FD-NKRIVSGAYDGKIKVWDL 533
Score = 51.2 bits (117), Expect = 4e-06
Identities = 39/152 (25%), Positives = 68/152 (44%), Gaps = 1/152 (0%)
Frame = -2
Query: 592 IVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDG 413
IVS D T+K+W + K GH+G + + + D + +G D +WD+N G
Sbjct: 316 IVSGLRDNTIKIWDKNTLECKRILTGHTG--SVLCLQYDERVIITGSSDSTVRVWDVNTG 373
Query: 412 KHLHTLDHN-DIITALCFSPNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKT 236
+ L+TL H+ + + L F+ C+ SI +WD+ S + R + ++ +
Sbjct: 374 EMLNTLIHHCEAVLHLRFNNGMMVTCSK-DRSIAVWDMASPTDITLRRVLVGHRAAVNVV 432
Query: 235 DPPQCLSLAWSTDGQTLFAGYSDNTIRVWQVS 140
D D + + + D TI+VW S
Sbjct: 433 D----------FDDKYIVSASGDRTIKVWNTS 454
Score = 51.2 bits (117), Expect = 4e-06
Identities = 51/202 (25%), Positives = 90/202 (44%), Gaps = 6/202 (2%)
Frame = -2
Query: 718 GSRDKTIKLW--NTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 545
G RD TIK+W NTL ECK + GH+ V C+++ +I++ D TV+VW +
Sbjct: 319 GLRDNTIKIWDKNTL-ECKRIL--TGHTGSVLCLQYDER----VIITGSSDSTVRVWDVN 371
Query: 544 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLH----TLDHNDII 377
++ +N L H + + + + + KD +WD+ + + H +
Sbjct: 372 TGEM-LNTLIHHCEA-VLHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRRVLVGHRAAV 429
Query: 376 TALCFSPNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTD 197
+ F ++Y + A+ +IK+W+ + E V +T CL
Sbjct: 430 NVVDFD-DKYIVSASGDRTIKVWNTSTCEFV---------RTLNGHKRGIACLQYR---- 475
Query: 196 GQTLFAGYSDNTIRVWQVSISA 131
+ + +G SDNTIR+W + A
Sbjct: 476 DRLVVSGSSDNTIRLWDIECGA 497
>AL133387-2|CAH70019.1| 569|Homo sapiens beta-transducin repeat
containing protein.
Length = 569
Score = 61.7 bits (143), Expect = 3e-09
Identities = 41/141 (29%), Positives = 67/141 (47%), Gaps = 3/141 (2%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQDD--GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
S+D++I +W+ + T++ GH V+ V F + IVS DRT+KVW+ +
Sbjct: 364 SKDRSIAVWDMASPTDITLRRVLVGHRAAVNVVDFDDKY----IVSASGDRTIKVWNTST 419
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALC 365
C+ GH + + L SG D LWD+ G L L+ H +++ +
Sbjct: 420 CEFVRTLNGHKRGIACLQYRD--RLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIR 477
Query: 364 FSPNRYWLCAAFGPSIKIWDL 302
F N+ + A+ IK+WDL
Sbjct: 478 FD-NKRIVSGAYDGKIKVWDL 497
Score = 51.2 bits (117), Expect = 4e-06
Identities = 39/152 (25%), Positives = 68/152 (44%), Gaps = 1/152 (0%)
Frame = -2
Query: 592 IVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDG 413
IVS D T+K+W + K GH+G + + + D + +G D +WD+N G
Sbjct: 280 IVSGLRDNTIKIWDKNTLECKRILTGHTG--SVLCLQYDERVIITGSSDSTVRVWDVNTG 337
Query: 412 KHLHTLDHN-DIITALCFSPNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKT 236
+ L+TL H+ + + L F+ C+ SI +WD+ S + R + ++ +
Sbjct: 338 EMLNTLIHHCEAVLHLRFNNGMMVTCSK-DRSIAVWDMASPTDITLRRVLVGHRAAVNVV 396
Query: 235 DPPQCLSLAWSTDGQTLFAGYSDNTIRVWQVS 140
D D + + + D TI+VW S
Sbjct: 397 D----------FDDKYIVSASGDRTIKVWNTS 418
Score = 51.2 bits (117), Expect = 4e-06
Identities = 51/202 (25%), Positives = 90/202 (44%), Gaps = 6/202 (2%)
Frame = -2
Query: 718 GSRDKTIKLW--NTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 545
G RD TIK+W NTL ECK + GH+ V C+++ +I++ D TV+VW +
Sbjct: 283 GLRDNTIKIWDKNTL-ECKRIL--TGHTGSVLCLQYDER----VIITGSSDSTVRVWDVN 335
Query: 544 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLH----TLDHNDII 377
++ +N L H + + + + + KD +WD+ + + H +
Sbjct: 336 TGEM-LNTLIHHCEA-VLHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRRVLVGHRAAV 393
Query: 376 TALCFSPNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTD 197
+ F ++Y + A+ +IK+W+ + E V +T CL
Sbjct: 394 NVVDFD-DKYIVSASGDRTIKVWNTSTCEFV---------RTLNGHKRGIACLQYR---- 439
Query: 196 GQTLFAGYSDNTIRVWQVSISA 131
+ + +G SDNTIR+W + A
Sbjct: 440 DRLVVSGSSDNTIRLWDIECGA 461
>AL133387-1|CAH70020.1| 605|Homo sapiens beta-transducin repeat
containing protein.
Length = 605
Score = 61.7 bits (143), Expect = 3e-09
Identities = 41/141 (29%), Positives = 67/141 (47%), Gaps = 3/141 (2%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQDD--GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
S+D++I +W+ + T++ GH V+ V F + IVS DRT+KVW+ +
Sbjct: 400 SKDRSIAVWDMASPTDITLRRVLVGHRAAVNVVDFDDKY----IVSASGDRTIKVWNTST 455
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALC 365
C+ GH + + L SG D LWD+ G L L+ H +++ +
Sbjct: 456 CEFVRTLNGHKRGIACLQYRD--RLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIR 513
Query: 364 FSPNRYWLCAAFGPSIKIWDL 302
F N+ + A+ IK+WDL
Sbjct: 514 FD-NKRIVSGAYDGKIKVWDL 533
Score = 51.2 bits (117), Expect = 4e-06
Identities = 39/152 (25%), Positives = 68/152 (44%), Gaps = 1/152 (0%)
Frame = -2
Query: 592 IVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDG 413
IVS D T+K+W + K GH+G + + + D + +G D +WD+N G
Sbjct: 316 IVSGLRDNTIKIWDKNTLECKRILTGHTG--SVLCLQYDERVIITGSSDSTVRVWDVNTG 373
Query: 412 KHLHTLDHN-DIITALCFSPNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKT 236
+ L+TL H+ + + L F+ C+ SI +WD+ S + R + ++ +
Sbjct: 374 EMLNTLIHHCEAVLHLRFNNGMMVTCSK-DRSIAVWDMASPTDITLRRVLVGHRAAVNVV 432
Query: 235 DPPQCLSLAWSTDGQTLFAGYSDNTIRVWQVS 140
D D + + + D TI+VW S
Sbjct: 433 D----------FDDKYIVSASGDRTIKVWNTS 454
Score = 51.2 bits (117), Expect = 4e-06
Identities = 51/202 (25%), Positives = 90/202 (44%), Gaps = 6/202 (2%)
Frame = -2
Query: 718 GSRDKTIKLW--NTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 545
G RD TIK+W NTL ECK + GH+ V C+++ +I++ D TV+VW +
Sbjct: 319 GLRDNTIKIWDKNTL-ECKRIL--TGHTGSVLCLQYDER----VIITGSSDSTVRVWDVN 371
Query: 544 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLH----TLDHNDII 377
++ +N L H + + + + + KD +WD+ + + H +
Sbjct: 372 TGEM-LNTLIHHCEA-VLHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRRVLVGHRAAV 429
Query: 376 TALCFSPNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTD 197
+ F ++Y + A+ +IK+W+ + E V +T CL
Sbjct: 430 NVVDFD-DKYIVSASGDRTIKVWNTSTCEFV---------RTLNGHKRGIACLQYR---- 475
Query: 196 GQTLFAGYSDNTIRVWQVSISA 131
+ + +G SDNTIR+W + A
Sbjct: 476 DRLVVSGSSDNTIRLWDIECGA 497
>AF129530-1|AAF04464.1| 569|Homo sapiens F-box protein Fbw1A
protein.
Length = 569
Score = 61.7 bits (143), Expect = 3e-09
Identities = 41/141 (29%), Positives = 67/141 (47%), Gaps = 3/141 (2%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQDD--GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
S+D++I +W+ + T++ GH V+ V F + IVS DRT+KVW+ +
Sbjct: 364 SKDRSIAVWDMASPTDITLRRVLVGHRAAVNVVDFDDKY----IVSASGDRTIKVWNTST 419
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALC 365
C+ GH + + L SG D LWD+ G L L+ H +++ +
Sbjct: 420 CEFVRTLNGHKRGIACLQYRD--RLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIR 477
Query: 364 FSPNRYWLCAAFGPSIKIWDL 302
F N+ + A+ IK+WDL
Sbjct: 478 FD-NKRIVSGAYDGKIKVWDL 497
Score = 51.2 bits (117), Expect = 4e-06
Identities = 39/152 (25%), Positives = 68/152 (44%), Gaps = 1/152 (0%)
Frame = -2
Query: 592 IVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDG 413
IVS D T+K+W + K GH+G + + + D + +G D +WD+N G
Sbjct: 280 IVSGLRDNTIKIWDKNTLECKRILTGHTG--SVLCLQYDERVIITGSSDSTVRVWDVNTG 337
Query: 412 KHLHTLDHN-DIITALCFSPNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKT 236
+ L+TL H+ + + L F+ C+ SI +WD+ S + R + ++ +
Sbjct: 338 EMLNTLIHHCEAVLHLRFNNGMMVTCSK-DRSIAVWDMASPTDITLRRVLVGHRAAVNVV 396
Query: 235 DPPQCLSLAWSTDGQTLFAGYSDNTIRVWQVS 140
D D + + + D TI+VW S
Sbjct: 397 D----------FDDKYIVSASGDRTIKVWNTS 418
Score = 51.2 bits (117), Expect = 4e-06
Identities = 51/202 (25%), Positives = 90/202 (44%), Gaps = 6/202 (2%)
Frame = -2
Query: 718 GSRDKTIKLW--NTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 545
G RD TIK+W NTL ECK + GH+ V C+++ +I++ D TV+VW +
Sbjct: 283 GLRDNTIKIWDKNTL-ECKRIL--TGHTGSVLCLQYDER----VIITGSSDSTVRVWDVN 335
Query: 544 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLH----TLDHNDII 377
++ +N L H + + + + + KD +WD+ + + H +
Sbjct: 336 TGEM-LNTLIHHCEA-VLHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRRVLVGHRAAV 393
Query: 376 TALCFSPNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTD 197
+ F ++Y + A+ +IK+W+ + E V +T CL
Sbjct: 394 NVVDFD-DKYIVSASGDRTIKVWNTSTCEFV---------RTLNGHKRGIACLQYR---- 439
Query: 196 GQTLFAGYSDNTIRVWQVSISA 131
+ + +G SDNTIR+W + A
Sbjct: 440 DRLVVSGSSDNTIRLWDIECGA 461
>AF101784-1|AAD08702.1| 605|Homo sapiens b-TRCP variant
E3RS-IkappaB protein.
Length = 605
Score = 61.7 bits (143), Expect = 3e-09
Identities = 41/141 (29%), Positives = 67/141 (47%), Gaps = 3/141 (2%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQDD--GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
S+D++I +W+ + T++ GH V+ V F + IVS DRT+KVW+ +
Sbjct: 400 SKDRSIAVWDMASPTDITLRRVLVGHRAAVNVVDFDDKY----IVSASGDRTIKVWNTST 455
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALC 365
C+ GH + + L SG D LWD+ G L L+ H +++ +
Sbjct: 456 CEFVRTLNGHKRGIACLQYRD--RLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIR 513
Query: 364 FSPNRYWLCAAFGPSIKIWDL 302
F N+ + A+ IK+WDL
Sbjct: 514 FD-NKRIVSGAYDGKIKVWDL 533
Score = 51.2 bits (117), Expect = 4e-06
Identities = 39/152 (25%), Positives = 68/152 (44%), Gaps = 1/152 (0%)
Frame = -2
Query: 592 IVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDG 413
IVS D T+K+W + K GH+G + + + D + +G D +WD+N G
Sbjct: 316 IVSGLRDNTIKIWDKNTLECKRILTGHTG--SVLCLQYDERVIITGSSDSTVRVWDVNTG 373
Query: 412 KHLHTLDHN-DIITALCFSPNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKT 236
+ L+TL H+ + + L F+ C+ SI +WD+ S + R + ++ +
Sbjct: 374 EMLNTLIHHCEAVLHLRFNNGMMVTCSK-DRSIAVWDMASPTDITLRRVLVGHRAAVNVV 432
Query: 235 DPPQCLSLAWSTDGQTLFAGYSDNTIRVWQVS 140
D D + + + D TI+VW S
Sbjct: 433 D----------FDDKYIVSASGDRTIKVWNTS 454
Score = 51.2 bits (117), Expect = 4e-06
Identities = 51/202 (25%), Positives = 90/202 (44%), Gaps = 6/202 (2%)
Frame = -2
Query: 718 GSRDKTIKLW--NTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLT 545
G RD TIK+W NTL ECK + GH+ V C+++ +I++ D TV+VW +
Sbjct: 319 GLRDNTIKIWDKNTL-ECKRIL--TGHTGSVLCLQYDER----VIITGSSDSTVRVWDVN 371
Query: 544 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLH----TLDHNDII 377
++ +N L H + + + + + KD +WD+ + + H +
Sbjct: 372 TGEM-LNTLIHHCEA-VLHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRRVLVGHRAAV 429
Query: 376 TALCFSPNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTD 197
+ F ++Y + A+ +IK+W+ + E V +T CL
Sbjct: 430 NVVDFD-DKYIVSASGDRTIKVWNTSTCEFV---------RTLNGHKRGIACLQYR---- 475
Query: 196 GQTLFAGYSDNTIRVWQVSISA 131
+ + +G SDNTIR+W + A
Sbjct: 476 DRLVVSGSSDNTIRLWDIECGA 497
>BC025379-1|AAH25379.1| 571|Homo sapiens SPAG16 protein protein.
Length = 571
Score = 61.3 bits (142), Expect = 3e-09
Identities = 40/135 (29%), Positives = 65/135 (48%), Gaps = 4/135 (2%)
Frame = -2
Query: 697 KLWNTLA--ECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKIN 524
+LW L +C + GH+DW+S F P+ + + S G D TVK+W L +
Sbjct: 314 RLWKVLGLPKCNVLLTGFGHTDWLSDCCFHPS-GDKLATSSG-DTTVKLWDLCKGDCILT 371
Query: 523 HLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCFSP-NR 350
GHS + + T G+ AS D + +WD+N + TL H D + ++ F P +
Sbjct: 372 FEGHSRAVWSCTWHSCGNFVASSSLDKTSKIWDVNSERCRCTLYGHTDSVNSIEFFPFSN 431
Query: 349 YWLCAAFGPSIKIWD 305
L ++ ++ IWD
Sbjct: 432 TLLTSSADKTLSIWD 446
Score = 60.9 bits (141), Expect = 4e-09
Identities = 45/164 (27%), Positives = 68/164 (41%), Gaps = 2/164 (1%)
Frame = -2
Query: 634 VSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASG 455
VSCV P+ I+VSCG DR KV L C + + GH+ +L+ P G A+
Sbjct: 295 VSCVSMHPH--KDILVSCGEDRLWKVLGLPKCNVLLTGFGHTDWLSDCCFHPSGDKLATS 352
Query: 454 GKDMKAMLWDLNDGKHLHTLDHNDIITALC--FSPNRYWLCAAFGPSIKIWDLESKEMVE 281
D LWDL G + T + + C S + ++ + KIWD+ S E
Sbjct: 353 SGDTTVKLWDLCKGDCILTFEGHSRAVWSCTWHSCGNFVASSSLDKTSKIWDVNS----E 408
Query: 280 ELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVW 149
R + T + S+ + TL +D T+ +W
Sbjct: 409 RCRCTLYGHTDSVN-------SIEFFPFSNTLLTSSADKTLSIW 445
Score = 59.3 bits (137), Expect = 1e-08
Identities = 54/192 (28%), Positives = 88/192 (45%), Gaps = 3/192 (1%)
Frame = -2
Query: 715 SRDKTIKLWNTLAE-CKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
S DKT K+W+ +E C+ T+ GH+D V+ + F P +N ++ S D+T+ +W
Sbjct: 395 SLDKTSKIWDVNSERCRCTLY--GHTDSVNSIEFFP-FSNTLLTSSA-DKTLSIWDARTG 450
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDII-TALCF 362
+ + GH +N P G + AS LWD + ++D + F
Sbjct: 451 ICEQSLYGHMHSINDAIFDPRGHMIASCDACGVTKLWDFRKLLPIVSIDIGPSPGNEVNF 510
Query: 361 SPNRYWLCAAFGPS-IKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTL 185
+ L A G I + DL+S E+ + + E N+ T + +S DG+ L
Sbjct: 511 DSSGRVLAQASGNGVIHLLDLKSGEIHKLMGHE--NEAHT----------VVFSHDGEIL 558
Query: 184 FAGYSDNTIRVW 149
F+G SD T+R W
Sbjct: 559 FSGGSDGTVRTW 570
Score = 52.0 bits (119), Expect = 2e-06
Identities = 36/141 (25%), Positives = 61/141 (43%), Gaps = 4/141 (2%)
Frame = -2
Query: 715 SRDKTIKLWNTL-AECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
S D T+KLW+ +C T + + W SC S + + S D+T K+W + +
Sbjct: 353 SGDTTVKLWDLCKGDCILTFEGHSRAVW-SCTWHSCGN---FVASSSLDKTSKIWDVNSE 408
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCF 362
+ + GH+ +N++ P + + D +WD G +L H I F
Sbjct: 409 RCRCTLYGHTDSVNSIEFFPFSNTLLTSSADKTLSIWDARTGICEQSLYGHMHSINDAIF 468
Query: 361 SPNRYWL--CAAFGPSIKIWD 305
P + + C A G + K+WD
Sbjct: 469 DPRGHMIASCDACGVT-KLWD 488
>AF490390-1|AAM97147.1| 631|Homo sapiens sperm-associated WD repeat
protein protein.
Length = 631
Score = 61.3 bits (142), Expect = 3e-09
Identities = 45/164 (27%), Positives = 68/164 (41%), Gaps = 2/164 (1%)
Frame = -2
Query: 634 VSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASG 455
VSCV P+ I+VSCG DR KV L C + + GH+ +L+ P G A+
Sbjct: 355 VSCVSMQPH--KDILVSCGEDRLWKVLGLPKCNVLLTGFGHTDWLSDCCFHPSGDKLATS 412
Query: 454 GKDMKAMLWDLNDGKHLHTLDHNDIITALC--FSPNRYWLCAAFGPSIKIWDLESKEMVE 281
D LWDL G + T + + C S + ++ + KIWD+ S E
Sbjct: 413 SGDTTVKLWDLCTGDCILTFEGHSRAVWSCTWHSCGNFVASSSLDKTSKIWDVNS----E 468
Query: 280 ELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVW 149
R + T + S+ + TL +D T+ +W
Sbjct: 469 RCRCTLYGHTDSVN-------SIEFFPFSNTLLTSSADKTLSIW 505
Score = 61.3 bits (142), Expect = 3e-09
Identities = 40/135 (29%), Positives = 65/135 (48%), Gaps = 4/135 (2%)
Frame = -2
Query: 697 KLWNTLA--ECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKIN 524
+LW L +C + GH+DW+S F P+ + + S G D TVK+W L +
Sbjct: 374 RLWKVLGLPKCNVLLTGFGHTDWLSDCCFHPS-GDKLATSSG-DTTVKLWDLCTGDCILT 431
Query: 523 HLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCFSP-NR 350
GHS + + T G+ AS D + +WD+N + TL H D + ++ F P +
Sbjct: 432 FEGHSRAVWSCTWHSCGNFVASSSLDKTSKIWDVNSERCRCTLYGHTDSVNSIEFFPFSN 491
Query: 349 YWLCAAFGPSIKIWD 305
L ++ ++ IWD
Sbjct: 492 TLLTSSADKTLSIWD 506
Score = 59.3 bits (137), Expect = 1e-08
Identities = 54/192 (28%), Positives = 88/192 (45%), Gaps = 3/192 (1%)
Frame = -2
Query: 715 SRDKTIKLWNTLAE-CKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
S DKT K+W+ +E C+ T+ GH+D V+ + F P +N ++ S D+T+ +W
Sbjct: 455 SLDKTSKIWDVNSERCRCTLY--GHTDSVNSIEFFP-FSNTLLTSSA-DKTLSIWDARTG 510
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDII-TALCF 362
+ + GH +N P G + AS LWD + ++D + F
Sbjct: 511 ICEQSLYGHMHSINDAIFDPRGHMIASCDACGVTKLWDFRKLLPIVSIDIGPSPGNEVNF 570
Query: 361 SPNRYWLCAAFGPS-IKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTL 185
+ L A G I + DL+S E+ + + E N+ T + +S DG+ L
Sbjct: 571 DSSGRVLAQASGNGVIHLLDLKSGEIHKLMGHE--NEAHT----------VVFSHDGEIL 618
Query: 184 FAGYSDNTIRVW 149
F+G SD T+R W
Sbjct: 619 FSGGSDGTVRTW 630
Score = 52.0 bits (119), Expect = 2e-06
Identities = 36/141 (25%), Positives = 61/141 (43%), Gaps = 4/141 (2%)
Frame = -2
Query: 715 SRDKTIKLWNTLA-ECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
S D T+KLW+ +C T + + W SC S + + S D+T K+W + +
Sbjct: 413 SGDTTVKLWDLCTGDCILTFEGHSRAVW-SCTWHSCGN---FVASSSLDKTSKIWDVNSE 468
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCF 362
+ + GH+ +N++ P + + D +WD G +L H I F
Sbjct: 469 RCRCTLYGHTDSVNSIEFFPFSNTLLTSSADKTLSIWDARTGICEQSLYGHMHSINDAIF 528
Query: 361 SPNRYWL--CAAFGPSIKIWD 305
P + + C A G + K+WD
Sbjct: 529 DPRGHMIASCDACGVT-KLWD 548
>AF310672-1|AAM63956.1| 631|Homo sapiens PF20 variant 1a protein.
Length = 631
Score = 61.3 bits (142), Expect = 3e-09
Identities = 45/164 (27%), Positives = 68/164 (41%), Gaps = 2/164 (1%)
Frame = -2
Query: 634 VSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASG 455
VSCV P+ I+VSCG DR KV L C + + GH+ +L+ P G A+
Sbjct: 355 VSCVSMQPH--KDILVSCGEDRLWKVLGLPKCNVLLTGFGHTDWLSDCCFHPSGDKLATS 412
Query: 454 GKDMKAMLWDLNDGKHLHTLDHNDIITALC--FSPNRYWLCAAFGPSIKIWDLESKEMVE 281
D LWDL G + T + + C S + ++ + KIWD+ S E
Sbjct: 413 SGDTTVKLWDLCTGDCILTFEGHSRAVWSCTWHSCGNFVASSSLDKTSKIWDVNS----E 468
Query: 280 ELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVW 149
R + T + S+ + TL +D T+ +W
Sbjct: 469 RCRCTLYGHTDSVN-------SIEFFPFSNTLLTSSADKTLSIW 505
Score = 61.3 bits (142), Expect = 3e-09
Identities = 40/135 (29%), Positives = 65/135 (48%), Gaps = 4/135 (2%)
Frame = -2
Query: 697 KLWNTLA--ECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKIN 524
+LW L +C + GH+DW+S F P+ + + S G D TVK+W L +
Sbjct: 374 RLWKVLGLPKCNVLLTGFGHTDWLSDCCFHPS-GDKLATSSG-DTTVKLWDLCTGDCILT 431
Query: 523 HLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCFSP-NR 350
GHS + + T G+ AS D + +WD+N + TL H D + ++ F P +
Sbjct: 432 FEGHSRAVWSCTWHSCGNFVASSSLDKTSKIWDVNSERCRCTLYGHTDSVNSIEFFPFSN 491
Query: 349 YWLCAAFGPSIKIWD 305
L ++ ++ IWD
Sbjct: 492 TLLTSSADKTLSIWD 506
Score = 59.3 bits (137), Expect = 1e-08
Identities = 54/192 (28%), Positives = 88/192 (45%), Gaps = 3/192 (1%)
Frame = -2
Query: 715 SRDKTIKLWNTLAE-CKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
S DKT K+W+ +E C+ T+ GH+D V+ + F P +N ++ S D+T+ +W
Sbjct: 455 SLDKTSKIWDVNSERCRCTLY--GHTDSVNSIEFFP-FSNTLLTSSA-DKTLSIWDARTG 510
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDII-TALCF 362
+ + GH +N P G + AS LWD + ++D + F
Sbjct: 511 ICEQSLYGHMHSINDAIFDPRGHMIASCDACGVTKLWDFRKLLPIVSIDIGPSPGNEVNF 570
Query: 361 SPNRYWLCAAFGPS-IKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTL 185
+ L A G I + DL+S E+ + + E N+ T + +S DG+ L
Sbjct: 571 DSSGRVLAQASGNGVIHLLDLKSGEIHKLMGHE--NEAHT----------VVFSHDGEIL 618
Query: 184 FAGYSDNTIRVW 149
F+G SD T+R W
Sbjct: 619 FSGGSDGTVRTW 630
Score = 52.0 bits (119), Expect = 2e-06
Identities = 36/141 (25%), Positives = 61/141 (43%), Gaps = 4/141 (2%)
Frame = -2
Query: 715 SRDKTIKLWNTLA-ECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
S D T+KLW+ +C T + + W SC S + + S D+T K+W + +
Sbjct: 413 SGDTTVKLWDLCTGDCILTFEGHSRAVW-SCTWHSCGN---FVASSSLDKTSKIWDVNSE 468
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCF 362
+ + GH+ +N++ P + + D +WD G +L H I F
Sbjct: 469 RCRCTLYGHTDSVNSIEFFPFSNTLLTSSADKTLSIWDARTGICEQSLYGHMHSINDAIF 528
Query: 361 SPNRYWL--CAAFGPSIKIWD 305
P + + C A G + K+WD
Sbjct: 529 DPRGHMIASCDACGVT-KLWD 548
>EF560718-1|ABQ59028.1| 1205|Homo sapiens APAF1 protein protein.
Length = 1205
Score = 60.5 bits (140), Expect = 6e-09
Identities = 48/198 (24%), Positives = 81/198 (40%), Gaps = 8/198 (4%)
Frame = -2
Query: 715 SRDKTIKLWNTLA-ECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
S DK +K+WN++ E +T D HS+ V+C F+ + + ++ + D +K+W L
Sbjct: 676 SVDKKVKIWNSMTGELVHTY--DEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLNQK 733
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDIITALCFS 359
+ + GH+ +N SPD L AS D LWD +++ L
Sbjct: 734 ECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKSINVKQFFLNL-ED 792
Query: 358 PNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLS-LAW------ST 200
P S W + ++ + +I S++ C L+W S
Sbjct: 793 PQEDMEVIVKCCS---WSADGARIMVAAKNKIFLWNTDSRSKVADCRGHLSWVHGVMFSP 849
Query: 199 DGQTLFAGYSDNTIRVWQ 146
DG + D TIR+W+
Sbjct: 850 DGSSFLTSSDDQTIRLWE 867
Score = 52.4 bits (120), Expect = 2e-06
Identities = 49/194 (25%), Positives = 84/194 (43%), Gaps = 3/194 (1%)
Frame = -2
Query: 715 SRDKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
S D I++WN L +C + GH + V R N ++S +D TVKVW++
Sbjct: 979 SDDAEIQVWNWQLDKCIFL---RGHQETVKDFRLLKNSR---LLSWSFDGTVKVWNIITG 1032
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCF 362
+ + + H G + + +S D + +S D A +W + LH L HN + F
Sbjct: 1033 NKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELRGHNGCVRCSAF 1092
Query: 361 SPNRYWLCAA-FGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTL 185
S + L I+IW++ + E++ P + + T L +S DG+ L
Sbjct: 1093 SVDSTLLATGDDNGEIRIWNVSNGELLHLCAP---LSEEGAATHGGWVTDLCFSPDGKML 1149
Query: 184 FAGYSDNTIRVWQV 143
+ + I+ W V
Sbjct: 1150 IS--AGGYIKWWNV 1161
Score = 50.8 bits (116), Expect = 5e-06
Identities = 41/155 (26%), Positives = 65/155 (41%), Gaps = 4/155 (2%)
Frame = -2
Query: 646 HSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSL 467
H+D V FS + I SCG D+T++V+ + H + S D
Sbjct: 614 HTDAVYHACFSEDDQR--IASCGADKTLQVFKAETGGKLLEIKAHEDEVLCCAFSTDDRF 671
Query: 466 CASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALCFSPNRYWLCAAFGPS---IKIWDLE 299
A+ D K +W+ G+ +HT D H++ + F+ + + L A G S +K+WDL
Sbjct: 672 IATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLN 731
Query: 298 SKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDG 194
KE + N + P L + S DG
Sbjct: 732 QKECRNTMFGH-TNSVNHCRFSPDDKLLASCSADG 765
Score = 41.5 bits (93), Expect = 0.003
Identities = 40/153 (26%), Positives = 70/153 (45%), Gaps = 15/153 (9%)
Frame = -2
Query: 718 GSRDKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
GS D +KLW+ EC+ T+ GH++ V+ RFSP+ + ++ SC D T+K+W T+
Sbjct: 719 GSSDCFLKLWDLNQKECRNTMF--GHTNSVNHCRFSPD--DKLLASCSADGTLKLWDATS 774
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSL---CASGGKD---------MKAMLWDLND-GKHLH 401
+ + +LN D + C S D K LW+ + K
Sbjct: 775 ANERKSINVKQFFLNLEDPQEDMEVIVKCCSWSADGARIMVAAKNKIFLWNTDSRSKVAD 834
Query: 400 TLDHNDIITALCFSPN-RYWLCAAFGPSIKIWD 305
H + + FSP+ +L ++ +I++W+
Sbjct: 835 CRGHLSWVHGVMFSPDGSSFLTSSDDQTIRLWE 867
>BC037320-1|AAH37320.1| 621|Homo sapiens FBXW7 protein protein.
Length = 621
Score = 60.5 bits (140), Expect = 6e-09
Identities = 47/193 (24%), Positives = 87/193 (45%), Gaps = 1/193 (0%)
Frame = -2
Query: 718 GSRDKTIKLWNT-LAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
GSRD T+++W+ +C + + GH V CVR+ +VS +D VKVW
Sbjct: 391 GSRDATLRVWDIETGQCLHVLM--GHVAAVRCVRYDGRR----VVSGAYDFMVKVWDPET 444
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDIITALCF 362
GH+ + ++ DG SG D +WD+ G +HTL + +T+
Sbjct: 445 ETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGME 502
Query: 361 SPNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLF 182
+ + ++KIWD+++ + ++ L+ N+ Q++ T CL + +
Sbjct: 503 LKDNILVSGNADSTVKIWDIKTGQCLQTLQGP--NKHQSAVT----CLQF----NKNFVI 552
Query: 181 AGYSDNTIRVWQV 143
D T+++W +
Sbjct: 553 TSSDDGTVKLWDL 565
Score = 58.8 bits (136), Expect = 2e-08
Identities = 53/194 (27%), Positives = 90/194 (46%), Gaps = 2/194 (1%)
Frame = -2
Query: 718 GSRDKTIKLWNTLA-ECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
GS D T+K+W+ + +C T+ GH+ V +S + II+S DRT+KVW+
Sbjct: 311 GSDDNTLKVWSAVTGKCLRTLV--GHTGGV----WSSQMRDNIIISGSTDRTLKVWNAET 364
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALC 365
+ GH+ + + + SG +D +WD+ G+ LH L H + +
Sbjct: 365 GECIHTLYGHTSTVRCMHLHE--KRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVR 422
Query: 364 FSPNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTL 185
+ R + A+ +K+WD E++ + L Q T++ SL + DG +
Sbjct: 423 YDGRRV-VSGAYDFMVKVWDPETETCLHTL------QGHTNRV-----YSLQF--DGIHV 468
Query: 184 FAGYSDNTIRVWQV 143
+G D +IRVW V
Sbjct: 469 VSGSLDTSIRVWDV 482
Score = 47.6 bits (108), Expect = 4e-05
Identities = 33/128 (25%), Positives = 59/128 (46%), Gaps = 2/128 (1%)
Frame = -2
Query: 652 DGHSDWV-SCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPD 476
+GH D V +C++F N IVS D T+KVW K +GH+G +
Sbjct: 291 NGHDDHVITCLQFCGNR----IVSGSDDNTLKVWSAVTGKCLRTLVGHTG--GVWSSQMR 344
Query: 475 GSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCFSPNRYWLCAAFGPSIKIWDLE 299
++ SG D +W+ G+ +HTL H + + R + + ++++WD+E
Sbjct: 345 DNIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLHEKRV-VSGSRDATLRVWDIE 403
Query: 298 SKEMVEEL 275
+ + + L
Sbjct: 404 TGQCLHVL 411
>AJ243007-1|CAB55583.1| 1205|Homo sapiens apoptotic protease
activating factor 1 protein.
Length = 1205
Score = 60.5 bits (140), Expect = 6e-09
Identities = 48/198 (24%), Positives = 81/198 (40%), Gaps = 8/198 (4%)
Frame = -2
Query: 715 SRDKTIKLWNTLA-ECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
S DK +K+WN++ E +T D HS+ V+C F+ + + ++ + D +K+W L
Sbjct: 676 SVDKKVKIWNSMTGELVHTY--DEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLNQK 733
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDIITALCFS 359
+ + GH+ +N SPD L AS D LWD +++ L
Sbjct: 734 ECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKSINVKQFFLNL-ED 792
Query: 358 PNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLS-LAW------ST 200
P S W + ++ + +I S++ C L+W S
Sbjct: 793 PQEDMEVIVKCCS---WSADGARIMVAAKNKIFLWNTDSRSKVADCRGHLSWVHGVMFSP 849
Query: 199 DGQTLFAGYSDNTIRVWQ 146
DG + D TIR+W+
Sbjct: 850 DGSSFLTSSDDQTIRLWE 867
Score = 52.4 bits (120), Expect = 2e-06
Identities = 49/194 (25%), Positives = 84/194 (43%), Gaps = 3/194 (1%)
Frame = -2
Query: 715 SRDKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
S D I++WN L +C + GH + V R N ++S +D TVKVW++
Sbjct: 979 SDDAEIQVWNWQLDKCIFL---RGHQETVKDFRLLKNSR---LLSWSFDGTVKVWNIITG 1032
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCF 362
+ + + H G + + +S D + +S D A +W + LH L HN + F
Sbjct: 1033 NKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELRGHNGCVRCSAF 1092
Query: 361 SPNRYWLCAA-FGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTL 185
S + L I+IW++ + E++ P + + T L +S DG+ L
Sbjct: 1093 SVDSTLLATGDDNGEIRIWNVSNGELLHLCAP---LSEEGAATHGGWVTDLCFSPDGKML 1149
Query: 184 FAGYSDNTIRVWQV 143
+ + I+ W V
Sbjct: 1150 IS--AGGYIKWWNV 1161
Score = 50.8 bits (116), Expect = 5e-06
Identities = 41/155 (26%), Positives = 65/155 (41%), Gaps = 4/155 (2%)
Frame = -2
Query: 646 HSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSL 467
H+D V FS + I SCG D+T +V+ + + H + S D
Sbjct: 614 HTDAVYHACFSEDGQR--IASCGADKTFQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRF 671
Query: 466 CASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALCFSPNRYWLCAAFGPS---IKIWDLE 299
A+ D K +W+ G+ +HT D H++ + F+ + + L A G S +K+WDL
Sbjct: 672 IATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLN 731
Query: 298 SKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDG 194
KE + N + P L + S DG
Sbjct: 732 QKECRNTMFGH-TNSVNHCRFSPDDKLLASCSADG 765
Score = 41.5 bits (93), Expect = 0.003
Identities = 40/153 (26%), Positives = 70/153 (45%), Gaps = 15/153 (9%)
Frame = -2
Query: 718 GSRDKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
GS D +KLW+ EC+ T+ GH++ V+ RFSP+ + ++ SC D T+K+W T+
Sbjct: 719 GSSDCFLKLWDLNQKECRNTMF--GHTNSVNHCRFSPD--DKLLASCSADGTLKLWDATS 774
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSL---CASGGKD---------MKAMLWDLND-GKHLH 401
+ + +LN D + C S D K LW+ + K
Sbjct: 775 ANERKSINVKQFFLNLEDPQEDMEVIVKCCSWSADGARIMVAAKNKIFLWNTDSRSKVAD 834
Query: 400 TLDHNDIITALCFSPN-RYWLCAAFGPSIKIWD 305
H + + FSP+ +L ++ +I++W+
Sbjct: 835 CRGHLSWVHGVMFSPDGSSFLTSSDDQTIRLWE 867
>AJ243006-1|CAB55582.1| 1205|Homo sapiens apoptotic protease
activating factor 1 protein.
Length = 1205
Score = 60.5 bits (140), Expect = 6e-09
Identities = 48/198 (24%), Positives = 81/198 (40%), Gaps = 8/198 (4%)
Frame = -2
Query: 715 SRDKTIKLWNTLA-ECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
S DK +K+WN++ E +T D HS+ V+C F+ + + ++ + D +K+W L
Sbjct: 676 SVDKKVKIWNSMTGELVHTY--DEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLNQK 733
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDIITALCFS 359
+ + GH+ +N SPD L AS D LWD +++ L
Sbjct: 734 ECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKSINVKQFFLNL-ED 792
Query: 358 PNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLS-LAW------ST 200
P S W + ++ + +I S++ C L+W S
Sbjct: 793 PQEDMEVIVKCCS---WSADGARIMVAAKNKIFLWNTDSRSKVADCRGHLSWVHGVMFSP 849
Query: 199 DGQTLFAGYSDNTIRVWQ 146
DG + D TIR+W+
Sbjct: 850 DGSSFLTSSDDQTIRLWE 867
Score = 54.8 bits (126), Expect = 3e-07
Identities = 50/194 (25%), Positives = 85/194 (43%), Gaps = 3/194 (1%)
Frame = -2
Query: 715 SRDKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
S D I++WN L +C + GH + V R N P ++S +D TVKVW++
Sbjct: 979 SDDAEIQVWNWQLDKCIFL---RGHQETVKDFRLLKN---PRLLSWSFDGTVKVWNIITG 1032
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCF 362
+ + + H G + + +S D + +S D A +W + LH L HN + F
Sbjct: 1033 NKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELRGHNGCVRCSAF 1092
Query: 361 SPNRYWLCAA-FGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTL 185
S + L I+IW++ + E++ P + + T L +S DG+ L
Sbjct: 1093 SVDSTLLATGDDNGEIRIWNVSNGELLHLCAP---LSEEGAATHGGWVTDLCFSPDGKML 1149
Query: 184 FAGYSDNTIRVWQV 143
+ + I+ W V
Sbjct: 1150 IS--AGGYIKWWNV 1161
Score = 51.6 bits (118), Expect = 3e-06
Identities = 41/155 (26%), Positives = 66/155 (42%), Gaps = 4/155 (2%)
Frame = -2
Query: 646 HSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSL 467
H+D V FS + I SCG D+T++V+ + + H + S D
Sbjct: 614 HTDAVYHACFSEDGQR--IASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRF 671
Query: 466 CASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALCFSPNRYWLCAAFGPS---IKIWDLE 299
A+ D K +W+ G+ +HT D H++ + F+ + + L A G S +K+WDL
Sbjct: 672 IATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLN 731
Query: 298 SKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDG 194
KE + N + P L + S DG
Sbjct: 732 QKECRNTMFGH-TNSVNHCRFSPDDKLLASCSADG 765
Score = 41.5 bits (93), Expect = 0.003
Identities = 40/153 (26%), Positives = 70/153 (45%), Gaps = 15/153 (9%)
Frame = -2
Query: 718 GSRDKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
GS D +KLW+ EC+ T+ GH++ V+ RFSP+ + ++ SC D T+K+W T+
Sbjct: 719 GSSDCFLKLWDLNQKECRNTMF--GHTNSVNHCRFSPD--DKLLASCSADGTLKLWDATS 774
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSL---CASGGKD---------MKAMLWDLND-GKHLH 401
+ + +LN D + C S D K LW+ + K
Sbjct: 775 ANERKSINVKQFFLNLEDPQEDMEVIVKCCSWSADGARIMVAAKNKIFLWNTDSRSKVAD 834
Query: 400 TLDHNDIITALCFSPN-RYWLCAAFGPSIKIWD 305
H + + FSP+ +L ++ +I++W+
Sbjct: 835 CRGHLSWVHGVMFSPDGSSFLTSSDDQTIRLWE 867
>AJ243004-1|CAB55580.1| 1205|Homo sapiens apoptotic protease
activating factor 1 protein.
Length = 1205
Score = 60.5 bits (140), Expect = 6e-09
Identities = 48/198 (24%), Positives = 81/198 (40%), Gaps = 8/198 (4%)
Frame = -2
Query: 715 SRDKTIKLWNTLA-ECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
S DK +K+WN++ E +T D HS+ V+C F+ + + ++ + D +K+W L
Sbjct: 676 SVDKKVKIWNSMTGELVHTY--DEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLNQK 733
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDIITALCFS 359
+ + GH+ +N SPD L AS D LWD +++ L
Sbjct: 734 ECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKSINVKQFFLNL-ED 792
Query: 358 PNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLS-LAW------ST 200
P S W + ++ + +I S++ C L+W S
Sbjct: 793 PQEDMEVIVKCCS---WSADGARIMVAAKNKIFLWNTDSRSKVADCRGHLSWVHGVMFSP 849
Query: 199 DGQTLFAGYSDNTIRVWQ 146
DG + D TIR+W+
Sbjct: 850 DGSSFLTSSDDQTIRLWE 867
Score = 52.4 bits (120), Expect = 2e-06
Identities = 49/194 (25%), Positives = 84/194 (43%), Gaps = 3/194 (1%)
Frame = -2
Query: 715 SRDKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
S D I++WN L +C + GH + V R N ++S +D TVKVW++
Sbjct: 979 SDDAEIQVWNWQLDKCIFL---RGHQETVKDFRLLKNSR---LLSWSFDGTVKVWNIITG 1032
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCF 362
+ + + H G + + +S D + +S D A +W + LH L HN + F
Sbjct: 1033 NKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELRGHNGCVRCSAF 1092
Query: 361 SPNRYWLCAA-FGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTL 185
S + L I+IW++ + E++ P + + T L +S DG+ L
Sbjct: 1093 SVDSTLLATGDDNGEIRIWNVSNGELLHLCAP---LSEEGAATHGGWVTDLCFSPDGKML 1149
Query: 184 FAGYSDNTIRVWQV 143
+ + I+ W V
Sbjct: 1150 IS--AGGYIKWWNV 1161
Score = 51.6 bits (118), Expect = 3e-06
Identities = 41/155 (26%), Positives = 66/155 (42%), Gaps = 4/155 (2%)
Frame = -2
Query: 646 HSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSL 467
H+D V FS + I SCG D+T++V+ + + H + S D
Sbjct: 614 HTDAVYHACFSEDGQR--IASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRF 671
Query: 466 CASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALCFSPNRYWLCAAFGPS---IKIWDLE 299
A+ D K +W+ G+ +HT D H++ + F+ + + L A G S +K+WDL
Sbjct: 672 IATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLN 731
Query: 298 SKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDG 194
KE + N + P L + S DG
Sbjct: 732 QKECRNTMFGH-TNSVNHCRFSPDDKLLASCSADG 765
Score = 41.5 bits (93), Expect = 0.003
Identities = 40/153 (26%), Positives = 70/153 (45%), Gaps = 15/153 (9%)
Frame = -2
Query: 718 GSRDKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
GS D +KLW+ EC+ T+ GH++ V+ RFSP+ + ++ SC D T+K+W T+
Sbjct: 719 GSSDCFLKLWDLNQKECRNTMF--GHTNSVNHCRFSPD--DKLLASCSADGTLKLWDATS 774
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSL---CASGGKD---------MKAMLWDLND-GKHLH 401
+ + +LN D + C S D K LW+ + K
Sbjct: 775 ANERKSINVKQFFLNLEDPQEDMEVIVKCCSWSADGARIMVAAKNKIFLWNTDSRSKVAD 834
Query: 400 TLDHNDIITALCFSPN-RYWLCAAFGPSIKIWD 305
H + + FSP+ +L ++ +I++W+
Sbjct: 835 CRGHLSWVHGVMFSPDGSSFLTSSDDQTIRLWE 867
>AJ243003-1|CAB55579.1| 1205|Homo sapiens apoptotic protease
activating factor 1 protein.
Length = 1205
Score = 60.5 bits (140), Expect = 6e-09
Identities = 48/198 (24%), Positives = 81/198 (40%), Gaps = 8/198 (4%)
Frame = -2
Query: 715 SRDKTIKLWNTLA-ECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
S DK +K+WN++ E +T D HS+ V+C F+ + + ++ + D +K+W L
Sbjct: 676 SVDKKVKIWNSMTGELVHTY--DEHSEQVNCCHFANSSHHLLLATGSSDCFLKLWDLNQK 733
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDIITALCFS 359
+ + GH+ +N SPD L AS D LWD +++ L
Sbjct: 734 ECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKSINVKQFFLNL-ED 792
Query: 358 PNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLS-LAW------ST 200
P S W + ++ + +I S++ C L+W S
Sbjct: 793 PQEDMEVIVKCCS---WSADGARIMVAAKNKIFLWNTDSRSKVADCRGHLSWVHGVMFSP 849
Query: 199 DGQTLFAGYSDNTIRVWQ 146
DG + D TIR+W+
Sbjct: 850 DGSSFLTSSDDQTIRLWE 867
Score = 52.4 bits (120), Expect = 2e-06
Identities = 49/194 (25%), Positives = 84/194 (43%), Gaps = 3/194 (1%)
Frame = -2
Query: 715 SRDKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
S D I++WN L +C + GH + V R N ++S +D TVKVW++
Sbjct: 979 SDDAEIQVWNWQLDKCIFL---RGHQETVKDFRLLKNSR---LLSWSFDGTVKVWNIITG 1032
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCF 362
+ + + H G + + +S D + +S D A +W + LH L HN + F
Sbjct: 1033 NKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELRGHNGCVRCSAF 1092
Query: 361 SPNRYWLCAA-FGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTL 185
S + L I+IW++ + E++ P + + T L +S DG+ L
Sbjct: 1093 SVDSTLLATGDDNGEIRIWNVSNGELLHLCAP---LSEEGAATHGGWVTDLCFSPDGKML 1149
Query: 184 FAGYSDNTIRVWQV 143
+ + I+ W V
Sbjct: 1150 IS--AGGYIKWWNV 1161
Score = 51.6 bits (118), Expect = 3e-06
Identities = 41/155 (26%), Positives = 66/155 (42%), Gaps = 4/155 (2%)
Frame = -2
Query: 646 HSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSL 467
H+D V FS + I SCG D+T++V+ + + H + S D
Sbjct: 614 HTDAVYHACFSEDGQR--IASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRF 671
Query: 466 CASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALCFSPNRYWLCAAFGPS---IKIWDLE 299
A+ D K +W+ G+ +HT D H++ + F+ + + L A G S +K+WDL
Sbjct: 672 IATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFANSSHHLLLATGSSDCFLKLWDLN 731
Query: 298 SKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDG 194
KE + N + P L + S DG
Sbjct: 732 QKECRNTMFGH-TNSVNHCRFSPDDKLLASCSADG 765
Score = 41.5 bits (93), Expect = 0.003
Identities = 40/153 (26%), Positives = 70/153 (45%), Gaps = 15/153 (9%)
Frame = -2
Query: 718 GSRDKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
GS D +KLW+ EC+ T+ GH++ V+ RFSP+ + ++ SC D T+K+W T+
Sbjct: 719 GSSDCFLKLWDLNQKECRNTMF--GHTNSVNHCRFSPD--DKLLASCSADGTLKLWDATS 774
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSL---CASGGKD---------MKAMLWDLND-GKHLH 401
+ + +LN D + C S D K LW+ + K
Sbjct: 775 ANERKSINVKQFFLNLEDPQEDMEVIVKCCSWSADGARIMVAAKNKIFLWNTDSRSKVAD 834
Query: 400 TLDHNDIITALCFSPN-RYWLCAAFGPSIKIWD 305
H + + FSP+ +L ++ +I++W+
Sbjct: 835 CRGHLSWVHGVMFSPDGSSFLTSSDDQTIRLWE 867
>AF013263-1|AAC51678.1| 1194|Homo sapiens apoptotic protease
activating factor 1 protein.
Length = 1194
Score = 60.5 bits (140), Expect = 6e-09
Identities = 48/198 (24%), Positives = 81/198 (40%), Gaps = 8/198 (4%)
Frame = -2
Query: 715 SRDKTIKLWNTLA-ECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
S DK +K+WN++ E +T D HS+ V+C F+ + + ++ + D +K+W L
Sbjct: 665 SVDKKVKIWNSMTGELVHTY--DEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLNQK 722
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDIITALCFS 359
+ + GH+ +N SPD L AS D LWD +++ L
Sbjct: 723 ECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKSINVKQFFLNL-ED 781
Query: 358 PNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLS-LAW------ST 200
P S W + ++ + +I S++ C L+W S
Sbjct: 782 PQEDMEVIVKCCS---WSADGARIMVAAKNKIFLWNTDSRSKVADCRGHLSWVHGVMFSP 838
Query: 199 DGQTLFAGYSDNTIRVWQ 146
DG + D TIR+W+
Sbjct: 839 DGSSFLTSSDDQTIRLWE 856
Score = 52.4 bits (120), Expect = 2e-06
Identities = 49/194 (25%), Positives = 84/194 (43%), Gaps = 3/194 (1%)
Frame = -2
Query: 715 SRDKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
S D I++WN L +C + GH + V R N ++S +D TVKVW++
Sbjct: 968 SDDAEIQVWNWQLDKCIFL---RGHQETVKDFRLLKNSR---LLSWSFDGTVKVWNIITG 1021
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCF 362
+ + + H G + + +S D + +S D A +W + LH L HN + F
Sbjct: 1022 NKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELRGHNGCVRCSAF 1081
Query: 361 SPNRYWLCAA-FGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTL 185
S + L I+IW++ + E++ P + + T L +S DG+ L
Sbjct: 1082 SVDSTLLATGDDNGEIRIWNVSNGELLHLCAP---LSEEGAATHGGWVTDLCFSPDGKML 1138
Query: 184 FAGYSDNTIRVWQV 143
+ + I+ W V
Sbjct: 1139 IS--AGGYIKWWNV 1150
Score = 51.6 bits (118), Expect = 3e-06
Identities = 41/155 (26%), Positives = 66/155 (42%), Gaps = 4/155 (2%)
Frame = -2
Query: 646 HSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSL 467
H+D V FS + I SCG D+T++V+ + + H + S D
Sbjct: 603 HTDAVYHACFSEDGQR--IASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRF 660
Query: 466 CASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALCFSPNRYWLCAAFGPS---IKIWDLE 299
A+ D K +W+ G+ +HT D H++ + F+ + + L A G S +K+WDL
Sbjct: 661 IATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLN 720
Query: 298 SKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDG 194
KE + N + P L + S DG
Sbjct: 721 QKECRNTMFGH-TNSVNHCRFSPDDKLLASCSADG 754
Score = 41.5 bits (93), Expect = 0.003
Identities = 40/153 (26%), Positives = 70/153 (45%), Gaps = 15/153 (9%)
Frame = -2
Query: 718 GSRDKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
GS D +KLW+ EC+ T+ GH++ V+ RFSP+ + ++ SC D T+K+W T+
Sbjct: 708 GSSDCFLKLWDLNQKECRNTMF--GHTNSVNHCRFSPD--DKLLASCSADGTLKLWDATS 763
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSL---CASGGKD---------MKAMLWDLND-GKHLH 401
+ + +LN D + C S D K LW+ + K
Sbjct: 764 ANERKSINVKQFFLNLEDPQEDMEVIVKCCSWSADGARIMVAAKNKIFLWNTDSRSKVAD 823
Query: 400 TLDHNDIITALCFSPN-RYWLCAAFGPSIKIWD 305
H + + FSP+ +L ++ +I++W+
Sbjct: 824 CRGHLSWVHGVMFSPDGSSFLTSSDDQTIRLWE 856
>AJ243011-1|CAB55587.1| 1205|Homo sapiens protease activating factor-1
protein.
Length = 1205
Score = 59.7 bits (138), Expect = 1e-08
Identities = 48/200 (24%), Positives = 82/200 (41%), Gaps = 10/200 (5%)
Frame = -2
Query: 715 SRDKTIKLWNTLA-ECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
S DK +K+WN++ E +T D HS+ V+C F+ + + ++ + D +K+W L
Sbjct: 676 SVDKKVKIWNSMTGELVHTY--DEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLNQK 733
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDIITALCFS 359
+ + GH+ +N SPD L AS D LWD +++ L
Sbjct: 734 ECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKSINVKQFFLNL-ED 792
Query: 358 PNRYWLCAAFGPSIKI--WDLESKEMVEELRPEIINQTQTSKTDPPQCLS-LAW------ 206
P G +K W + ++ + +I ++ C L+W
Sbjct: 793 PQE-----DMGVIVKCCSWSADGARIMVAAKNKIFLWNTDLRSKVADCRGHLSWVHGVMF 847
Query: 205 STDGQTLFAGYSDNTIRVWQ 146
S DG + D TIR+W+
Sbjct: 848 SPDGSSFLTSSDDQTIRLWE 867
Score = 52.4 bits (120), Expect = 2e-06
Identities = 49/194 (25%), Positives = 84/194 (43%), Gaps = 3/194 (1%)
Frame = -2
Query: 715 SRDKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
S D I++WN L +C + GH + V R N ++S +D TVKVW++
Sbjct: 979 SDDAEIQVWNWQLDKCIFL---RGHQETVKDFRLLKNSR---LLSWSFDGTVKVWNIITG 1032
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCF 362
+ + + H G + + +S D + +S D A +W + LH L HN + F
Sbjct: 1033 NKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELRGHNGCVRCSAF 1092
Query: 361 SPNRYWLCAA-FGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTL 185
S + L I+IW++ + E++ P + + T L +S DG+ L
Sbjct: 1093 SVDSTLLATGDDNGEIRIWNVSNGELLHLCAP---LSEEGAATHGGWVTDLCFSPDGKML 1149
Query: 184 FAGYSDNTIRVWQV 143
+ + I+ W V
Sbjct: 1150 IS--AGGYIKWWNV 1161
Score = 51.6 bits (118), Expect = 3e-06
Identities = 41/155 (26%), Positives = 66/155 (42%), Gaps = 4/155 (2%)
Frame = -2
Query: 646 HSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSL 467
H+D V FS + I SCG D+T++V+ + + H + S D
Sbjct: 614 HTDAVYRACFSEDGQR--IASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRF 671
Query: 466 CASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALCFSPNRYWLCAAFGPS---IKIWDLE 299
A+ D K +W+ G+ +HT D H++ + F+ + + L A G S +K+WDL
Sbjct: 672 IATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLN 731
Query: 298 SKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDG 194
KE + N + P L + S DG
Sbjct: 732 QKECRNTMFGH-TNSVNHCRFSPDDKLLASCSADG 765
Score = 41.1 bits (92), Expect = 0.004
Identities = 23/60 (38%), Positives = 37/60 (61%), Gaps = 1/60 (1%)
Frame = -2
Query: 718 GSRDKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
GS D +KLW+ EC+ T+ GH++ V+ RFSP+ + ++ SC D T+K+W T+
Sbjct: 719 GSSDCFLKLWDLNQKECRNTMF--GHTNSVNHCRFSPD--DKLLASCSADGTLKLWDATS 774
>AJ243010-1|CAB55586.1| 1205|Homo sapiens apoptotic protease
activating factor 1 protein.
Length = 1205
Score = 59.7 bits (138), Expect = 1e-08
Identities = 48/198 (24%), Positives = 80/198 (40%), Gaps = 8/198 (4%)
Frame = -2
Query: 715 SRDKTIKLWNTLA-ECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
S DK +K+WN++ E +T D HS+ V+C F+ + + ++ + D +K+W L
Sbjct: 676 SVDKKVKIWNSMTGELVHTY--DEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLNQK 733
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDIITALCFS 359
+ + GH+ N SPD L AS D LWD +++ L
Sbjct: 734 ECRNTMFGHTNSANHCRFSPDDKLLASCSADGTLKLWDATSANERKSINVKQFFLNL-ED 792
Query: 358 PNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLS-LAW------ST 200
P S W + ++ + +I S++ C L+W S
Sbjct: 793 PQEDMEVIVKCCS---WSADGARIMVAAKNKIFLWNTDSRSKVADCRGHLSWVHGVMFSP 849
Query: 199 DGQTLFAGYSDNTIRVWQ 146
DG + D TIR+W+
Sbjct: 850 DGSSFLTSSDDQTIRLWE 867
Score = 52.4 bits (120), Expect = 2e-06
Identities = 44/173 (25%), Positives = 77/173 (44%), Gaps = 4/173 (2%)
Frame = -2
Query: 646 HSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSL 467
H+D V FS + I SCG D+T++V+ + + H + S D
Sbjct: 614 HTDAVYHACFSEDGQR--IASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRF 671
Query: 466 CASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALCFSPNRYWLCAAFGPS---IKIWDLE 299
A+ D K +W+ G+ +HT D H++ + F+ + + L A G S +K+WDL
Sbjct: 672 IATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLN 731
Query: 298 SKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQVS 140
K E R + T ++ C +S D + L + +D T+++W +
Sbjct: 732 QK----ECRNTMFGHTNSAN----HC---RFSPDDKLLASCSADGTLKLWDAT 773
Score = 52.4 bits (120), Expect = 2e-06
Identities = 49/194 (25%), Positives = 84/194 (43%), Gaps = 3/194 (1%)
Frame = -2
Query: 715 SRDKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
S D I++WN L +C + GH + V R N ++S +D TVKVW++
Sbjct: 979 SDDAEIQVWNWQLDKCIFL---RGHQETVKDFRLLKNSR---LLSWSFDGTVKVWNIITG 1032
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCF 362
+ + + H G + + +S D + +S D A +W + LH L HN + F
Sbjct: 1033 NKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELRGHNGCVRCSAF 1092
Query: 361 SPNRYWLCAA-FGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTL 185
S + L I+IW++ + E++ P + + T L +S DG+ L
Sbjct: 1093 SVDSTLLATGDDNGEIRIWNVSNGELLHLCAP---LSEEGAATHGGWVTDLCFSPDGKML 1149
Query: 184 FAGYSDNTIRVWQV 143
+ + I+ W V
Sbjct: 1150 IS--AGGYIKWWNV 1161
Score = 39.9 bits (89), Expect = 0.009
Identities = 39/153 (25%), Positives = 69/153 (45%), Gaps = 15/153 (9%)
Frame = -2
Query: 718 GSRDKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
GS D +KLW+ EC+ T+ GH++ + RFSP+ + ++ SC D T+K+W T+
Sbjct: 719 GSSDCFLKLWDLNQKECRNTMF--GHTNSANHCRFSPD--DKLLASCSADGTLKLWDATS 774
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSL---CASGGKD---------MKAMLWDLND-GKHLH 401
+ + +LN D + C S D K LW+ + K
Sbjct: 775 ANERKSINVKQFFLNLEDPQEDMEVIVKCCSWSADGARIMVAAKNKIFLWNTDSRSKVAD 834
Query: 400 TLDHNDIITALCFSPN-RYWLCAAFGPSIKIWD 305
H + + FSP+ +L ++ +I++W+
Sbjct: 835 CRGHLSWVHGVMFSPDGSSFLTSSDDQTIRLWE 867
>AJ243005-1|CAB55581.1| 1205|Homo sapiens apoptotic protease
activating factor 1 protein.
Length = 1205
Score = 59.7 bits (138), Expect = 1e-08
Identities = 46/198 (23%), Positives = 80/198 (40%), Gaps = 8/198 (4%)
Frame = -2
Query: 715 SRDKTIKLWNTLA-ECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
S DK +K+WN++ E +T D HS+ V+C F+ + + ++ + D +K+W L
Sbjct: 676 SVDKKVKIWNSMTGELVHTY--DEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLNQK 733
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDIITALCFS 359
+ + GH+ +N SPD L AS D LWD +++ L
Sbjct: 734 ECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKSINVKQFFLNLEDP 793
Query: 358 PNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLS-LAW------ST 200
+ W + ++ + +I S++ C L+W S
Sbjct: 794 QGDMEVIV----KCCSWSADGARIMVAAKNKIFLWNTDSRSKVTDCRGHLSWVHGVMFSP 849
Query: 199 DGQTLFAGYSDNTIRVWQ 146
DG + D TIR+W+
Sbjct: 850 DGSSFLTSSDDQTIRLWE 867
Score = 52.4 bits (120), Expect = 2e-06
Identities = 49/194 (25%), Positives = 84/194 (43%), Gaps = 3/194 (1%)
Frame = -2
Query: 715 SRDKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
S D I++WN L +C + GH + V R N ++S +D TVKVW++
Sbjct: 979 SDDAEIQVWNWQLDKCIFL---RGHQETVKDFRLLKNSR---LLSWSFDGTVKVWNIITG 1032
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCF 362
+ + + H G + + +S D + +S D A +W + LH L HN + F
Sbjct: 1033 NKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELRGHNGCVRCSAF 1092
Query: 361 SPNRYWLCAA-FGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTL 185
S + L I+IW++ + E++ P + + T L +S DG+ L
Sbjct: 1093 SVDSTLLATGDDNGEIRIWNVSNGELLHLCAP---LSEEGAATHGGWVTDLCFSPDGKML 1149
Query: 184 FAGYSDNTIRVWQV 143
+ + I+ W V
Sbjct: 1150 IS--AGGYIKWWNV 1161
Score = 51.6 bits (118), Expect = 3e-06
Identities = 41/155 (26%), Positives = 66/155 (42%), Gaps = 4/155 (2%)
Frame = -2
Query: 646 HSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSL 467
H+D V FS + I SCG D+T++V+ + + H + S D
Sbjct: 614 HTDAVYHACFSEDGQR--IASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRF 671
Query: 466 CASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALCFSPNRYWLCAAFGPS---IKIWDLE 299
A+ D K +W+ G+ +HT D H++ + F+ + + L A G S +K+WDL
Sbjct: 672 IATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLN 731
Query: 298 SKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDG 194
KE + N + P L + S DG
Sbjct: 732 QKECRNTMFGH-TNSVNHCRFSPDDKLLASCSADG 765
Score = 41.1 bits (92), Expect = 0.004
Identities = 23/60 (38%), Positives = 37/60 (61%), Gaps = 1/60 (1%)
Frame = -2
Query: 718 GSRDKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
GS D +KLW+ EC+ T+ GH++ V+ RFSP+ + ++ SC D T+K+W T+
Sbjct: 719 GSSDCFLKLWDLNQKECRNTMF--GHTNSVNHCRFSPD--DKLLASCSADGTLKLWDATS 774
>BC117246-1|AAI17247.1| 707|Homo sapiens F-box and WD repeat domain
containing 7 protein.
Length = 707
Score = 58.8 bits (136), Expect = 2e-08
Identities = 53/194 (27%), Positives = 90/194 (46%), Gaps = 2/194 (1%)
Frame = -2
Query: 718 GSRDKTIKLWNTLA-ECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
GS D T+K+W+ + +C T+ GH+ V +S + II+S DRT+KVW+
Sbjct: 397 GSDDNTLKVWSAVTGKCLRTLV--GHTGGV----WSSQMRDNIIISGSTDRTLKVWNAET 450
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALC 365
+ GH+ + + + SG +D +WD+ G+ LH L H + +
Sbjct: 451 GECIHTLYGHTSTVRCMHLHE--KRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQ 508
Query: 364 FSPNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTL 185
+ R + A+ +K+WD E++ + L Q T++ SL + DG +
Sbjct: 509 YDGRRV-VSGAYDFMVKVWDPETETCLHTL------QGHTNRV-----YSLQF--DGIHV 554
Query: 184 FAGYSDNTIRVWQV 143
+G D +IRVW V
Sbjct: 555 VSGSLDTSIRVWDV 568
Score = 58.8 bits (136), Expect = 2e-08
Identities = 46/193 (23%), Positives = 87/193 (45%), Gaps = 1/193 (0%)
Frame = -2
Query: 718 GSRDKTIKLWNT-LAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
GSRD T+++W+ +C + + GH V CV++ +VS +D VKVW
Sbjct: 477 GSRDATLRVWDIETGQCLHVLM--GHVAAVRCVQYDGRR----VVSGAYDFMVKVWDPET 530
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDIITALCF 362
GH+ + ++ DG SG D +WD+ G +HTL + +T+
Sbjct: 531 ETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGME 588
Query: 361 SPNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLF 182
+ + ++KIWD+++ + ++ L+ N+ Q++ T CL + +
Sbjct: 589 LKDNILVSGNADSTVKIWDIKTGQCLQTLQGP--NKHQSAVT----CLQF----NKNFVI 638
Query: 181 AGYSDNTIRVWQV 143
D T+++W +
Sbjct: 639 TSSDDGTVKLWDL 651
Score = 47.2 bits (107), Expect = 6e-05
Identities = 33/127 (25%), Positives = 58/127 (45%), Gaps = 2/127 (1%)
Frame = -2
Query: 649 GHSDWV-SCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDG 473
GH D V +C++F N IVS D T+KVW K +GH+G +
Sbjct: 378 GHDDHVITCLQFCGNR----IVSGSDDNTLKVWSAVTGKCLRTLVGHTG--GVWSSQMRD 431
Query: 472 SLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCFSPNRYWLCAAFGPSIKIWDLES 296
++ SG D +W+ G+ +HTL H + + R + + ++++WD+E+
Sbjct: 432 NIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLHEKRV-VSGSRDATLRVWDIET 490
Query: 295 KEMVEEL 275
+ + L
Sbjct: 491 GQCLHVL 497
>BC117244-1|AAI17245.1| 707|Homo sapiens F-box and WD repeat domain
containing 7 protein.
Length = 707
Score = 58.8 bits (136), Expect = 2e-08
Identities = 53/194 (27%), Positives = 90/194 (46%), Gaps = 2/194 (1%)
Frame = -2
Query: 718 GSRDKTIKLWNTLA-ECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
GS D T+K+W+ + +C T+ GH+ V +S + II+S DRT+KVW+
Sbjct: 397 GSDDNTLKVWSAVTGKCLRTLV--GHTGGV----WSSQMRDNIIISGSTDRTLKVWNAET 450
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALC 365
+ GH+ + + + SG +D +WD+ G+ LH L H + +
Sbjct: 451 GECIHTLYGHTSTVRCMHLHE--KRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQ 508
Query: 364 FSPNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTL 185
+ R + A+ +K+WD E++ + L Q T++ SL + DG +
Sbjct: 509 YDGRRV-VSGAYDFMVKVWDPETETCLHTL------QGHTNRV-----YSLQF--DGIHV 554
Query: 184 FAGYSDNTIRVWQV 143
+G D +IRVW V
Sbjct: 555 VSGSLDTSIRVWDV 568
Score = 58.8 bits (136), Expect = 2e-08
Identities = 46/193 (23%), Positives = 87/193 (45%), Gaps = 1/193 (0%)
Frame = -2
Query: 718 GSRDKTIKLWNT-LAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
GSRD T+++W+ +C + + GH V CV++ +VS +D VKVW
Sbjct: 477 GSRDATLRVWDIETGQCLHVLM--GHVAAVRCVQYDGRR----VVSGAYDFMVKVWDPET 530
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDIITALCF 362
GH+ + ++ DG SG D +WD+ G +HTL + +T+
Sbjct: 531 ETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGME 588
Query: 361 SPNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLF 182
+ + ++KIWD+++ + ++ L+ N+ Q++ T CL + +
Sbjct: 589 LKDNILVSGNADSTVKIWDIKTGQCLQTLQGP--NKHQSAVT----CLQF----NKNFVI 638
Query: 181 AGYSDNTIRVWQV 143
D T+++W +
Sbjct: 639 TSSDDGTVKLWDL 651
Score = 47.2 bits (107), Expect = 6e-05
Identities = 33/127 (25%), Positives = 58/127 (45%), Gaps = 2/127 (1%)
Frame = -2
Query: 649 GHSDWV-SCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDG 473
GH D V +C++F N IVS D T+KVW K +GH+G +
Sbjct: 378 GHDDHVITCLQFCGNR----IVSGSDDNTLKVWSAVTGKCLRTLVGHTG--GVWSSQMRD 431
Query: 472 SLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCFSPNRYWLCAAFGPSIKIWDLES 296
++ SG D +W+ G+ +HTL H + + R + + ++++WD+E+
Sbjct: 432 NIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLHEKRV-VSGSRDATLRVWDIET 490
Query: 295 KEMVEEL 275
+ + L
Sbjct: 491 GQCLHVL 497
>AY049984-1|AAL07271.1| 707|Homo sapiens F-box protein CDC4
protein.
Length = 707
Score = 58.8 bits (136), Expect = 2e-08
Identities = 53/194 (27%), Positives = 90/194 (46%), Gaps = 2/194 (1%)
Frame = -2
Query: 718 GSRDKTIKLWNTLA-ECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
GS D T+K+W+ + +C T+ GH+ V +S + II+S DRT+KVW+
Sbjct: 397 GSDDNTLKVWSAVTGKCLRTLV--GHTGGV----WSSQMRDNIIISGSTDRTLKVWNAET 450
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALC 365
+ GH+ + + + SG +D +WD+ G+ LH L H + +
Sbjct: 451 GECIHTLYGHTSTVRCMHLHE--KRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQ 508
Query: 364 FSPNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTL 185
+ R + A+ +K+WD E++ + L Q T++ SL + DG +
Sbjct: 509 YDGRRV-VSGAYDFMVKVWDPETETCLHTL------QGHTNRV-----YSLQF--DGIHV 554
Query: 184 FAGYSDNTIRVWQV 143
+G D +IRVW V
Sbjct: 555 VSGSLDTSIRVWDV 568
Score = 58.8 bits (136), Expect = 2e-08
Identities = 46/193 (23%), Positives = 87/193 (45%), Gaps = 1/193 (0%)
Frame = -2
Query: 718 GSRDKTIKLWNT-LAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
GSRD T+++W+ +C + + GH V CV++ +VS +D VKVW
Sbjct: 477 GSRDATLRVWDIETGQCLHVLM--GHVAAVRCVQYDGRR----VVSGAYDFMVKVWDPET 530
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDIITALCF 362
GH+ + ++ DG SG D +WD+ G +HTL + +T+
Sbjct: 531 ETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGME 588
Query: 361 SPNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLF 182
+ + ++KIWD+++ + ++ L+ N+ Q++ T CL + +
Sbjct: 589 LKDNILVSGNADSTVKIWDIKTGQCLQTLQGP--NKHQSAVT----CLQF----NKNFVI 638
Query: 181 AGYSDNTIRVWQV 143
D T+++W +
Sbjct: 639 TSSDDGTVKLWDL 651
Score = 47.2 bits (107), Expect = 6e-05
Identities = 33/127 (25%), Positives = 58/127 (45%), Gaps = 2/127 (1%)
Frame = -2
Query: 649 GHSDWV-SCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDG 473
GH D V +C++F N IVS D T+KVW K +GH+G +
Sbjct: 378 GHDDHVITCLQFCGNR----IVSGSDDNTLKVWSAVTGKCLRTLVGHTG--GVWSSQMRD 431
Query: 472 SLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCFSPNRYWLCAAFGPSIKIWDLES 296
++ SG D +W+ G+ +HTL H + + R + + ++++WD+E+
Sbjct: 432 NIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLHEKRV-VSGSRDATLRVWDIET 490
Query: 295 KEMVEEL 275
+ + L
Sbjct: 491 GQCLHVL 497
>AY033553-1|AAK57547.1| 627|Homo sapiens F-box protein FBW7
protein.
Length = 627
Score = 58.8 bits (136), Expect = 2e-08
Identities = 53/194 (27%), Positives = 90/194 (46%), Gaps = 2/194 (1%)
Frame = -2
Query: 718 GSRDKTIKLWNTLA-ECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
GS D T+K+W+ + +C T+ GH+ V +S + II+S DRT+KVW+
Sbjct: 317 GSDDNTLKVWSAVTGKCLRTLV--GHTGGV----WSSQMRDNIIISGSTDRTLKVWNAET 370
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALC 365
+ GH+ + + + SG +D +WD+ G+ LH L H + +
Sbjct: 371 GECIHTLYGHTSTVRCMHLHE--KRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQ 428
Query: 364 FSPNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTL 185
+ R + A+ +K+WD E++ + L Q T++ SL + DG +
Sbjct: 429 YDGRRV-VSGAYDFMVKVWDPETETCLHTL------QGHTNRV-----YSLQF--DGIHV 474
Query: 184 FAGYSDNTIRVWQV 143
+G D +IRVW V
Sbjct: 475 VSGSLDTSIRVWDV 488
Score = 58.8 bits (136), Expect = 2e-08
Identities = 46/193 (23%), Positives = 87/193 (45%), Gaps = 1/193 (0%)
Frame = -2
Query: 718 GSRDKTIKLWNT-LAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
GSRD T+++W+ +C + + GH V CV++ +VS +D VKVW
Sbjct: 397 GSRDATLRVWDIETGQCLHVLM--GHVAAVRCVQYDGRR----VVSGAYDFMVKVWDPET 450
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDIITALCF 362
GH+ + ++ DG SG D +WD+ G +HTL + +T+
Sbjct: 451 ETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGME 508
Query: 361 SPNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLF 182
+ + ++KIWD+++ + ++ L+ N+ Q++ T CL + +
Sbjct: 509 LKDNILVSGNADSTVKIWDIKTGQCLQTLQGP--NKHQSAVT----CLQF----NKNFVI 558
Query: 181 AGYSDNTIRVWQV 143
D T+++W +
Sbjct: 559 TSSDDGTVKLWDL 571
Score = 47.2 bits (107), Expect = 6e-05
Identities = 33/127 (25%), Positives = 58/127 (45%), Gaps = 2/127 (1%)
Frame = -2
Query: 649 GHSDWV-SCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDG 473
GH D V +C++F N IVS D T+KVW K +GH+G +
Sbjct: 298 GHDDHVITCLQFCGNR----IVSGSDDNTLKVWSAVTGKCLRTLVGHTG--GVWSSQMRD 351
Query: 472 SLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCFSPNRYWLCAAFGPSIKIWDLES 296
++ SG D +W+ G+ +HTL H + + R + + ++++WD+E+
Sbjct: 352 NIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLHEKRV-VSGSRDATLRVWDIET 410
Query: 295 KEMVEEL 275
+ + L
Sbjct: 411 GQCLHVL 417
>AY008274-1|AAG16640.1| 589|Homo sapiens F-box protein SEL10
protein.
Length = 589
Score = 58.8 bits (136), Expect = 2e-08
Identities = 53/194 (27%), Positives = 90/194 (46%), Gaps = 2/194 (1%)
Frame = -2
Query: 718 GSRDKTIKLWNTLA-ECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
GS D T+K+W+ + +C T+ GH+ V +S + II+S DRT+KVW+
Sbjct: 279 GSDDNTLKVWSAVTGKCLRTLV--GHTGGV----WSSQMRDNIIISGSTDRTLKVWNAET 332
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALC 365
+ GH+ + + + SG +D +WD+ G+ LH L H + +
Sbjct: 333 GECIHTLYGHTSTVRCMHLHE--KRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQ 390
Query: 364 FSPNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTL 185
+ R + A+ +K+WD E++ + L Q T++ SL + DG +
Sbjct: 391 YDGRRV-VSGAYDFMVKVWDPETETCLHTL------QGHTNRV-----YSLQF--DGIHV 436
Query: 184 FAGYSDNTIRVWQV 143
+G D +IRVW V
Sbjct: 437 VSGSLDTSIRVWDV 450
Score = 58.8 bits (136), Expect = 2e-08
Identities = 46/193 (23%), Positives = 87/193 (45%), Gaps = 1/193 (0%)
Frame = -2
Query: 718 GSRDKTIKLWNT-LAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
GSRD T+++W+ +C + + GH V CV++ +VS +D VKVW
Sbjct: 359 GSRDATLRVWDIETGQCLHVLM--GHVAAVRCVQYDGRR----VVSGAYDFMVKVWDPET 412
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDIITALCF 362
GH+ + ++ DG SG D +WD+ G +HTL + +T+
Sbjct: 413 ETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGME 470
Query: 361 SPNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLF 182
+ + ++KIWD+++ + ++ L+ N+ Q++ T CL + +
Sbjct: 471 LKDNILVSGNADSTVKIWDIKTGQCLQTLQGP--NKHQSAVT----CLQF----NKNFVI 520
Query: 181 AGYSDNTIRVWQV 143
D T+++W +
Sbjct: 521 TSSDDGTVKLWDL 533
Score = 47.2 bits (107), Expect = 6e-05
Identities = 33/127 (25%), Positives = 58/127 (45%), Gaps = 2/127 (1%)
Frame = -2
Query: 649 GHSDWV-SCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDG 473
GH D V +C++F N IVS D T+KVW K +GH+G +
Sbjct: 260 GHDDHVITCLQFCGNR----IVSGSDDNTLKVWSAVTGKCLRTLVGHTG--GVWSSQMRD 313
Query: 472 SLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCFSPNRYWLCAAFGPSIKIWDLES 296
++ SG D +W+ G+ +HTL H + + R + + ++++WD+E+
Sbjct: 314 NIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLHEKRV-VSGSRDATLRVWDIET 372
Query: 295 KEMVEEL 275
+ + L
Sbjct: 373 GQCLHVL 379
>AK223449-1|BAD97169.1| 627|Homo sapiens F-box protein FBW7 isoform
2 variant protein.
Length = 627
Score = 58.8 bits (136), Expect = 2e-08
Identities = 53/194 (27%), Positives = 90/194 (46%), Gaps = 2/194 (1%)
Frame = -2
Query: 718 GSRDKTIKLWNTLA-ECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
GS D T+K+W+ + +C T+ GH+ V +S + II+S DRT+KVW+
Sbjct: 317 GSDDNTLKVWSAVTGKCLRTLV--GHTGGV----WSSQMRDNIIISGSTDRTLKVWNAET 370
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALC 365
+ GH+ + + + SG +D +WD+ G+ LH L H + +
Sbjct: 371 GECIHTLYGHTSTVRCMHLHE--KRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQ 428
Query: 364 FSPNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTL 185
+ R + A+ +K+WD E++ + L Q T++ SL + DG +
Sbjct: 429 YDGRRV-VSGAYDFMVKVWDPETETCLHTL------QGHTNRV-----YSLQF--DGIHV 474
Query: 184 FAGYSDNTIRVWQV 143
+G D +IRVW V
Sbjct: 475 VSGSLDTSIRVWDV 488
Score = 58.8 bits (136), Expect = 2e-08
Identities = 46/193 (23%), Positives = 87/193 (45%), Gaps = 1/193 (0%)
Frame = -2
Query: 718 GSRDKTIKLWNT-LAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
GSRD T+++W+ +C + + GH V CV++ +VS +D VKVW
Sbjct: 397 GSRDATLRVWDIETGQCLHVLM--GHVAAVRCVQYDGRR----VVSGAYDFMVKVWDPET 450
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDIITALCF 362
GH+ + ++ DG SG D +WD+ G +HTL + +T+
Sbjct: 451 ETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGME 508
Query: 361 SPNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLF 182
+ + ++KIWD+++ + ++ L+ N+ Q++ T CL + +
Sbjct: 509 LKDNILVSGNADSTVKIWDIKTGQCLQTLQGP--NKHQSAVT----CLQF----NKNFVI 558
Query: 181 AGYSDNTIRVWQV 143
D T+++W +
Sbjct: 559 TSSDDGTVKLWDL 571
Score = 47.2 bits (107), Expect = 6e-05
Identities = 33/127 (25%), Positives = 58/127 (45%), Gaps = 2/127 (1%)
Frame = -2
Query: 649 GHSDWV-SCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDG 473
GH D V +C++F N IVS D T+KVW K +GH+G +
Sbjct: 298 GHDDHVITCLQFCGNR----IVSGSDDNTLKVWSAVTGKCLRTLVGHTG--GVWSSQMRD 351
Query: 472 SLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCFSPNRYWLCAAFGPSIKIWDLES 296
++ SG D +W+ G+ +HTL H + + R + + ++++WD+E+
Sbjct: 352 NIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLHEKRV-VSGSRDATLRVWDIET 410
Query: 295 KEMVEEL 275
+ + L
Sbjct: 411 GQCLHVL 417
>AK001933-1|BAA91986.1| 553|Homo sapiens protein ( Homo sapiens
cDNA FLJ11071 fis, clone PLACE1004937, moderately
similar to SEL-10 PROTEIN. ).
Length = 553
Score = 58.8 bits (136), Expect = 2e-08
Identities = 53/194 (27%), Positives = 90/194 (46%), Gaps = 2/194 (1%)
Frame = -2
Query: 718 GSRDKTIKLWNTLA-ECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
GS D T+K+W+ + +C T+ GH+ V +S + II+S DRT+KVW+
Sbjct: 243 GSDDNTLKVWSAVTGKCLRTLV--GHTGGV----WSSQMRDNIIISGSTDRTLKVWNAET 296
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALC 365
+ GH+ + + + SG +D +WD+ G+ LH L H + +
Sbjct: 297 GECIHTLYGHTSTVRCMHLHE--KRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQ 354
Query: 364 FSPNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTL 185
+ R + A+ +K+WD E++ + L Q T++ SL + DG +
Sbjct: 355 YDGRRV-VSGAYDFMVKVWDPETETCLHTL------QGHTNRV-----YSLQF--DGIHV 400
Query: 184 FAGYSDNTIRVWQV 143
+G D +IRVW V
Sbjct: 401 VSGSLDTSIRVWDV 414
Score = 58.8 bits (136), Expect = 2e-08
Identities = 46/193 (23%), Positives = 87/193 (45%), Gaps = 1/193 (0%)
Frame = -2
Query: 718 GSRDKTIKLWNT-LAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
GSRD T+++W+ +C + + GH V CV++ +VS +D VKVW
Sbjct: 323 GSRDATLRVWDIETGQCLHVLM--GHVAAVRCVQYDGRR----VVSGAYDFMVKVWDPET 376
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDIITALCF 362
GH+ + ++ DG SG D +WD+ G +HTL + +T+
Sbjct: 377 ETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGME 434
Query: 361 SPNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLF 182
+ + ++KIWD+++ + ++ L+ N+ Q++ T CL + +
Sbjct: 435 LKDNILVSGNADSTVKIWDIKTGQCLQTLQGP--NKHQSAVT----CLQF----NKNFVI 484
Query: 181 AGYSDNTIRVWQV 143
D T+++W +
Sbjct: 485 TSSDDGTVKLWDL 497
Score = 47.2 bits (107), Expect = 6e-05
Identities = 33/127 (25%), Positives = 58/127 (45%), Gaps = 2/127 (1%)
Frame = -2
Query: 649 GHSDWV-SCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDG 473
GH D V +C++F N IVS D T+KVW K +GH+G +
Sbjct: 224 GHDDHVITCLQFCGNR----IVSGSDDNTLKVWSAVTGKCLRTLVGHTG--GVWSSQMRD 277
Query: 472 SLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCFSPNRYWLCAAFGPSIKIWDLES 296
++ SG D +W+ G+ +HTL H + + R + + ++++WD+E+
Sbjct: 278 NIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLHEKRV-VSGSRDATLRVWDIET 336
Query: 295 KEMVEEL 275
+ + L
Sbjct: 337 GQCLHVL 343
>AF411972-1|AAL06291.1| 627|Homo sapiens archipelago beta form
protein.
Length = 627
Score = 58.8 bits (136), Expect = 2e-08
Identities = 53/194 (27%), Positives = 90/194 (46%), Gaps = 2/194 (1%)
Frame = -2
Query: 718 GSRDKTIKLWNTLA-ECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
GS D T+K+W+ + +C T+ GH+ V +S + II+S DRT+KVW+
Sbjct: 317 GSDDNTLKVWSAVTGKCLRTLV--GHTGGV----WSSQMRDNIIISGSTDRTLKVWNAET 370
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALC 365
+ GH+ + + + SG +D +WD+ G+ LH L H + +
Sbjct: 371 GECIHTLYGHTSTVRCMHLHE--KRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQ 428
Query: 364 FSPNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTL 185
+ R + A+ +K+WD E++ + L Q T++ SL + DG +
Sbjct: 429 YDGRRV-VSGAYDFMVKVWDPETETCLHTL------QGHTNRV-----YSLQF--DGIHV 474
Query: 184 FAGYSDNTIRVWQV 143
+G D +IRVW V
Sbjct: 475 VSGSLDTSIRVWDV 488
Score = 58.8 bits (136), Expect = 2e-08
Identities = 46/193 (23%), Positives = 87/193 (45%), Gaps = 1/193 (0%)
Frame = -2
Query: 718 GSRDKTIKLWNT-LAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
GSRD T+++W+ +C + + GH V CV++ +VS +D VKVW
Sbjct: 397 GSRDATLRVWDIETGQCLHVLM--GHVAAVRCVQYDGRR----VVSGAYDFMVKVWDPET 450
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDIITALCF 362
GH+ + ++ DG SG D +WD+ G +HTL + +T+
Sbjct: 451 ETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGME 508
Query: 361 SPNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLF 182
+ + ++KIWD+++ + ++ L+ N+ Q++ T CL + +
Sbjct: 509 LKDNILVSGNADSTVKIWDIKTGQCLQTLQGP--NKHQSAVT----CLQF----NKNFVI 558
Query: 181 AGYSDNTIRVWQV 143
D T+++W +
Sbjct: 559 TSSDDGTVKLWDL 571
Score = 47.2 bits (107), Expect = 6e-05
Identities = 33/127 (25%), Positives = 58/127 (45%), Gaps = 2/127 (1%)
Frame = -2
Query: 649 GHSDWV-SCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDG 473
GH D V +C++F N IVS D T+KVW K +GH+G +
Sbjct: 298 GHDDHVITCLQFCGNR----IVSGSDDNTLKVWSAVTGKCLRTLVGHTG--GVWSSQMRD 351
Query: 472 SLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCFSPNRYWLCAAFGPSIKIWDLES 296
++ SG D +W+ G+ +HTL H + + R + + ++++WD+E+
Sbjct: 352 NIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLHEKRV-VSGSRDATLRVWDIET 410
Query: 295 KEMVEEL 275
+ + L
Sbjct: 411 GQCLHVL 417
>AF411971-1|AAL06290.1| 707|Homo sapiens archipelago alpha form
protein.
Length = 707
Score = 58.8 bits (136), Expect = 2e-08
Identities = 53/194 (27%), Positives = 90/194 (46%), Gaps = 2/194 (1%)
Frame = -2
Query: 718 GSRDKTIKLWNTLA-ECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
GS D T+K+W+ + +C T+ GH+ V +S + II+S DRT+KVW+
Sbjct: 397 GSDDNTLKVWSAVTGKCLRTLV--GHTGGV----WSSQMRDNIIISGSTDRTLKVWNAET 450
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALC 365
+ GH+ + + + SG +D +WD+ G+ LH L H + +
Sbjct: 451 GECIHTLYGHTSTVRCMHLHE--KRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQ 508
Query: 364 FSPNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTL 185
+ R + A+ +K+WD E++ + L Q T++ SL + DG +
Sbjct: 509 YDGRRV-VSGAYDFMVKVWDPETETCLHTL------QGHTNRV-----YSLQF--DGIHV 554
Query: 184 FAGYSDNTIRVWQV 143
+G D +IRVW V
Sbjct: 555 VSGSLDTSIRVWDV 568
Score = 58.8 bits (136), Expect = 2e-08
Identities = 46/193 (23%), Positives = 87/193 (45%), Gaps = 1/193 (0%)
Frame = -2
Query: 718 GSRDKTIKLWNT-LAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
GSRD T+++W+ +C + + GH V CV++ +VS +D VKVW
Sbjct: 477 GSRDATLRVWDIETGQCLHVLM--GHVAAVRCVQYDGRR----VVSGAYDFMVKVWDPET 530
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDIITALCF 362
GH+ + ++ DG SG D +WD+ G +HTL + +T+
Sbjct: 531 ETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGME 588
Query: 361 SPNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLF 182
+ + ++KIWD+++ + ++ L+ N+ Q++ T CL + +
Sbjct: 589 LKDNILVSGNADSTVKIWDIKTGQCLQTLQGP--NKHQSAVT----CLQF----NKNFVI 638
Query: 181 AGYSDNTIRVWQV 143
D T+++W +
Sbjct: 639 TSSDDGTVKLWDL 651
Score = 47.2 bits (107), Expect = 6e-05
Identities = 33/127 (25%), Positives = 58/127 (45%), Gaps = 2/127 (1%)
Frame = -2
Query: 649 GHSDWV-SCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDG 473
GH D V +C++F N IVS D T+KVW K +GH+G +
Sbjct: 378 GHDDHVITCLQFCGNR----IVSGSDDNTLKVWSAVTGKCLRTLVGHTG--GVWSSQMRD 431
Query: 472 SLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCFSPNRYWLCAAFGPSIKIWDLES 296
++ SG D +W+ G+ +HTL H + + R + + ++++WD+E+
Sbjct: 432 NIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLHEKRV-VSGSRDATLRVWDIET 490
Query: 295 KEMVEEL 275
+ + L
Sbjct: 491 GQCLHVL 497
>AF383178-1|AAK60269.1| 561|Homo sapiens F-box protein FBX30
protein.
Length = 561
Score = 58.8 bits (136), Expect = 2e-08
Identities = 53/194 (27%), Positives = 90/194 (46%), Gaps = 2/194 (1%)
Frame = -2
Query: 718 GSRDKTIKLWNTLA-ECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
GS D T+K+W+ + +C T+ GH+ V +S + II+S DRT+KVW+
Sbjct: 251 GSDDNTLKVWSAVTGKCLRTLV--GHTGGV----WSSQMRDNIIISGSTDRTLKVWNAET 304
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALC 365
+ GH+ + + + SG +D +WD+ G+ LH L H + +
Sbjct: 305 GECIHTLYGHTSTVRCMHLHE--KRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQ 362
Query: 364 FSPNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTL 185
+ R + A+ +K+WD E++ + L Q T++ SL + DG +
Sbjct: 363 YDGRRV-VSGAYDFMVKVWDPETETCLHTL------QGHTNRV-----YSLQF--DGIHV 408
Query: 184 FAGYSDNTIRVWQV 143
+G D +IRVW V
Sbjct: 409 VSGSLDTSIRVWDV 422
Score = 58.8 bits (136), Expect = 2e-08
Identities = 46/193 (23%), Positives = 87/193 (45%), Gaps = 1/193 (0%)
Frame = -2
Query: 718 GSRDKTIKLWNT-LAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
GSRD T+++W+ +C + + GH V CV++ +VS +D VKVW
Sbjct: 331 GSRDATLRVWDIETGQCLHVLM--GHVAAVRCVQYDGRR----VVSGAYDFMVKVWDPET 384
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDIITALCF 362
GH+ + ++ DG SG D +WD+ G +HTL + +T+
Sbjct: 385 ETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGME 442
Query: 361 SPNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLF 182
+ + ++KIWD+++ + ++ L+ N+ Q++ T CL + +
Sbjct: 443 LKDNILVSGNADSTVKIWDIKTGQCLQTLQGP--NKHQSAVT----CLQF----NKNFVI 492
Query: 181 AGYSDNTIRVWQV 143
D T+++W +
Sbjct: 493 TSSDDGTVKLWDL 505
Score = 47.2 bits (107), Expect = 6e-05
Identities = 33/127 (25%), Positives = 58/127 (45%), Gaps = 2/127 (1%)
Frame = -2
Query: 649 GHSDWV-SCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDG 473
GH D V +C++F N IVS D T+KVW K +GH+G +
Sbjct: 232 GHDDHVITCLQFCGNR----IVSGSDDNTLKVWSAVTGKCLRTLVGHTG--GVWSSQMRD 285
Query: 472 SLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCFSPNRYWLCAAFGPSIKIWDLES 296
++ SG D +W+ G+ +HTL H + + R + + ++++WD+E+
Sbjct: 286 NIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLHEKRV-VSGSRDATLRVWDIET 344
Query: 295 KEMVEEL 275
+ + L
Sbjct: 345 GQCLHVL 351
>AB209725-1|BAD92962.1| 624|Homo sapiens F-box protein FBW7 isoform
2 variant protein.
Length = 624
Score = 58.8 bits (136), Expect = 2e-08
Identities = 53/194 (27%), Positives = 90/194 (46%), Gaps = 2/194 (1%)
Frame = -2
Query: 718 GSRDKTIKLWNTLA-ECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
GS D T+K+W+ + +C T+ GH+ V +S + II+S DRT+KVW+
Sbjct: 314 GSDDNTLKVWSAVTGKCLRTLV--GHTGGV----WSSQMRDNIIISGSTDRTLKVWNAET 367
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALC 365
+ GH+ + + + SG +D +WD+ G+ LH L H + +
Sbjct: 368 GECIHTLYGHTSTVRCMHLHE--KRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQ 425
Query: 364 FSPNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTL 185
+ R + A+ +K+WD E++ + L Q T++ SL + DG +
Sbjct: 426 YDGRRV-VSGAYDFMVKVWDPETETCLHTL------QGHTNRV-----YSLQF--DGIHV 471
Query: 184 FAGYSDNTIRVWQV 143
+G D +IRVW V
Sbjct: 472 VSGSLDTSIRVWDV 485
Score = 58.8 bits (136), Expect = 2e-08
Identities = 46/193 (23%), Positives = 87/193 (45%), Gaps = 1/193 (0%)
Frame = -2
Query: 718 GSRDKTIKLWNT-LAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
GSRD T+++W+ +C + + GH V CV++ +VS +D VKVW
Sbjct: 394 GSRDATLRVWDIETGQCLHVLM--GHVAAVRCVQYDGRR----VVSGAYDFMVKVWDPET 447
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDIITALCF 362
GH+ + ++ DG SG D +WD+ G +HTL + +T+
Sbjct: 448 ETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGME 505
Query: 361 SPNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLF 182
+ + ++KIWD+++ + ++ L+ N+ Q++ T CL + +
Sbjct: 506 LKDNILVSGNADSTVKIWDIKTGQCLQTLQGP--NKHQSAVT----CLQF----NKNFVI 555
Query: 181 AGYSDNTIRVWQV 143
D T+++W +
Sbjct: 556 TSSDDGTVKLWDL 568
Score = 47.2 bits (107), Expect = 6e-05
Identities = 33/127 (25%), Positives = 58/127 (45%), Gaps = 2/127 (1%)
Frame = -2
Query: 649 GHSDWV-SCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDG 473
GH D V +C++F N IVS D T+KVW K +GH+G +
Sbjct: 295 GHDDHVITCLQFCGNR----IVSGSDDNTLKVWSAVTGKCLRTLVGHTG--GVWSSQMRD 348
Query: 472 SLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCFSPNRYWLCAAFGPSIKIWDLES 296
++ SG D +W+ G+ +HTL H + + R + + ++++WD+E+
Sbjct: 349 NIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLHEKRV-VSGSRDATLRVWDIET 407
Query: 295 KEMVEEL 275
+ + L
Sbjct: 408 GQCLHVL 414
>M99435-1|AAA61192.1| 770|Homo sapiens transducin-like enhancer
protein protein.
Length = 770
Score = 58.4 bits (135), Expect = 2e-08
Identities = 36/133 (27%), Positives = 57/133 (42%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
G T+ +W+ LA I+ + S +C + + + + SC D + VW L N
Sbjct: 548 GGEASTLSIWD-LAAPTPRIKAELTSSAPACYALAISPDSKVCFSCCSDGNIAVWDLHNQ 606
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDIITALCFS 359
L GH+ + + +S DG+ +GG D WDL +G+ L D I +L +
Sbjct: 607 TLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVRSWDLREGRQLQQHDFTSQIFSLGYC 666
Query: 358 PNRYWLCAAFGPS 320
P WL S
Sbjct: 667 PTGEWLAVGMESS 679
Score = 46.4 bits (105), Expect = 1e-04
Identities = 41/159 (25%), Positives = 66/159 (41%), Gaps = 10/159 (6%)
Frame = -2
Query: 589 VSCGWDRTVKVWHLTNCKLK-----INHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWD 425
V G VKVW +++ K ++ L Y+ + + PDG GG+ +WD
Sbjct: 499 VYTGGKGCVKVWDISHPGNKSPVSQLDCLNRDNYIRSCKLLPDGCTLIVGGEASTLSIWD 558
Query: 424 L---NDGKHLHTLDHNDIITALCFSPNRY--WLCAAFGPSIKIWDLESKEMVEELRPEII 260
L AL SP+ + C + G +I +WDL ++ +V + +
Sbjct: 559 LAAPTPRIKAELTSSAPACYALAISPDSKVCFSCCSDG-NIAVWDLHNQTLVRQFQ---- 613
Query: 259 NQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQV 143
TD C+ + S DG L+ G DNT+R W +
Sbjct: 614 -----GHTDGASCIDI--SNDGTKLWTGGLDNTVRSWDL 645
Score = 35.5 bits (78), Expect = 0.19
Identities = 37/137 (27%), Positives = 57/137 (41%), Gaps = 7/137 (5%)
Frame = -2
Query: 532 KINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDG------KHLHTLDHNDIITA 371
+IN L H + VT+S +GGK +WD++ L L+ ++ I +
Sbjct: 477 QINTLNHGEVVCAVTISNPTRHVYTGGKGC-VKVWDISHPGNKSPVSQLDCLNRDNYIRS 535
Query: 370 LCFSPNRYWLCAAFGPS-IKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDG 194
P+ L S + IWDL + P I + +S P C +LA S D
Sbjct: 536 CKLLPDGCTLIVGGEASTLSIWDLAAPT------PRIKAELTSSA---PACYALAISPDS 586
Query: 193 QTLFAGYSDNTIRVWQV 143
+ F+ SD I VW +
Sbjct: 587 KVCFSCCSDGNIAVWDL 603
>BC015747-1|AAH15747.1| 770|Homo sapiens transducin-like enhancer
of split 1 (E(sp1) homolog, Drosophila) protein.
Length = 770
Score = 58.4 bits (135), Expect = 2e-08
Identities = 36/133 (27%), Positives = 57/133 (42%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
G T+ +W+ LA I+ + S +C + + + + SC D + VW L N
Sbjct: 548 GGEASTLSIWD-LAAPTPRIKAELTSSAPACYALAISPDSKVCFSCCSDGNIAVWDLHNQ 606
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDIITALCFS 359
L GH+ + + +S DG+ +GG D WDL +G+ L D I +L +
Sbjct: 607 TLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVRSWDLREGRQLQQHDFTSQIFSLGYC 666
Query: 358 PNRYWLCAAFGPS 320
P WL S
Sbjct: 667 PTGEWLAVGMESS 679
Score = 46.4 bits (105), Expect = 1e-04
Identities = 41/159 (25%), Positives = 66/159 (41%), Gaps = 10/159 (6%)
Frame = -2
Query: 589 VSCGWDRTVKVWHLTNCKLK-----INHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWD 425
V G VKVW +++ K ++ L Y+ + + PDG GG+ +WD
Sbjct: 499 VYTGGKGCVKVWDISHPGNKSPVSQLDCLNRDNYIRSCKLLPDGCTLIVGGEASTLSIWD 558
Query: 424 L---NDGKHLHTLDHNDIITALCFSPNRY--WLCAAFGPSIKIWDLESKEMVEELRPEII 260
L AL SP+ + C + G +I +WDL ++ +V + +
Sbjct: 559 LAAPTPRIKAELTSSAPACYALAISPDSKVCFSCCSDG-NIAVWDLHNQTLVRQFQ---- 613
Query: 259 NQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQV 143
TD C+ + S DG L+ G DNT+R W +
Sbjct: 614 -----GHTDGASCIDI--SNDGTKLWTGGLDNTVRSWDL 645
Score = 35.5 bits (78), Expect = 0.19
Identities = 37/137 (27%), Positives = 57/137 (41%), Gaps = 7/137 (5%)
Frame = -2
Query: 532 KINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDG------KHLHTLDHNDIITA 371
+IN L H + VT+S +GGK +WD++ L L+ ++ I +
Sbjct: 477 QINTLNHGEVVCAVTISNPTRHVYTGGKGC-VKVWDISHPGNKSPVSQLDCLNRDNYIRS 535
Query: 370 LCFSPNRYWLCAAFGPS-IKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDG 194
P+ L S + IWDL + P I + +S P C +LA S D
Sbjct: 536 CKLLPDGCTLIVGGEASTLSIWDLAAPT------PRIKAELTSSA---PACYALAISPDS 586
Query: 193 QTLFAGYSDNTIRVWQV 143
+ F+ SD I VW +
Sbjct: 587 KVCFSCCSDGNIAVWDL 603
>BC013997-1|AAH13997.1| 353|Homo sapiens guanine nucleotide binding
protein (G protein), beta 5 protein.
Length = 353
Score = 58.4 bits (135), Expect = 2e-08
Identities = 47/177 (26%), Positives = 86/177 (48%), Gaps = 4/177 (2%)
Frame = -2
Query: 646 HSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPD--G 473
H++++S F+ N I+ + G D T +W + + +L + GH + + ++P G
Sbjct: 152 HTNYLSACSFT-NSDMQILTASG-DGTCALWDVESGQLLQSFHGHGADVLCLDLAPSETG 209
Query: 472 SLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALCFSPNR-YWLCAAFGPSIKIWDLE 299
+ SGG D KAM+WD+ G+ + + H I ++ + P+ + + + +++DL
Sbjct: 210 NTFVSGGCDKKAMVWDMRSGQCVQAFETHESDINSVRYYPSGDAFASGSDDATCRLYDLR 269
Query: 298 SKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQVSISAR 128
+ V E I +S + +S G+ LFAGY+D TI VW V +R
Sbjct: 270 ADREVAIYSKESIIFGASS---------VDFSLSGRLLFAGYNDYTINVWDVLKGSR 317
Score = 56.4 bits (130), Expect = 1e-07
Identities = 52/194 (26%), Positives = 79/194 (40%), Gaps = 5/194 (2%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQD-DGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
S D T LW+ E +Q GH V C+ +P+ VS G D+ VW + +
Sbjct: 172 SGDGTCALWDV--ESGQLLQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDMRSG 229
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDII---TAL 368
+ H +N+V P G ASG D L+DL + + II +++
Sbjct: 230 QCVQAFETHESDINSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYSKESIIFGASSV 289
Query: 367 CFSPNRYWLCAAFGP-SIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQ 191
FS + L A + +I +WD+ V L N+ T + P DG
Sbjct: 290 DFSLSGRLLFAGYNDYTINVWDVLKGSRVSILFGH-ENRVSTLRVSP----------DGT 338
Query: 190 TLFAGYSDNTIRVW 149
+G D+T+RVW
Sbjct: 339 AFCSGSWDHTLRVW 352
Score = 35.5 bits (78), Expect = 0.19
Identities = 28/99 (28%), Positives = 45/99 (45%), Gaps = 2/99 (2%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDW-VSCVRFSPNHANPIIVSCGW-DRTVKVWHLT 545
GS D T +L++ A+ + I + S V FS + ++ G+ D T+ VW +
Sbjct: 257 GSDDATCRLYDLRADREVAIYSKESIIFGASSVDFSLSGR---LLFAGYNDYTINVWDVL 313
Query: 544 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLW 428
GH ++T+ VSPDG+ SG D +W
Sbjct: 314 KGSRVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLRVW 352
>BC010100-1|AAH10100.1| 770|Homo sapiens transducin-like enhancer
of split 1 (E(sp1) homolog, Drosophila) protein.
Length = 770
Score = 58.4 bits (135), Expect = 2e-08
Identities = 36/133 (27%), Positives = 57/133 (42%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
G T+ +W+ LA I+ + S +C + + + + SC D + VW L N
Sbjct: 548 GGEASTLSIWD-LAAPTPRIKAELTSSAPACYALAISPDSKVCFSCCSDGNIAVWDLHNQ 606
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDIITALCFS 359
L GH+ + + +S DG+ +GG D WDL +G+ L D I +L +
Sbjct: 607 TLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVRSWDLREGRQLQQHDFTSQIFSLGYC 666
Query: 358 PNRYWLCAAFGPS 320
P WL S
Sbjct: 667 PTGEWLAVGMESS 679
Score = 46.4 bits (105), Expect = 1e-04
Identities = 41/159 (25%), Positives = 66/159 (41%), Gaps = 10/159 (6%)
Frame = -2
Query: 589 VSCGWDRTVKVWHLTNCKLK-----INHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWD 425
V G VKVW +++ K ++ L Y+ + + PDG GG+ +WD
Sbjct: 499 VYTGGKGCVKVWDISHPGNKSPVSQLDCLNRDNYIRSCKLLPDGCTLIVGGEASTLSIWD 558
Query: 424 L---NDGKHLHTLDHNDIITALCFSPNRY--WLCAAFGPSIKIWDLESKEMVEELRPEII 260
L AL SP+ + C + G +I +WDL ++ +V + +
Sbjct: 559 LAAPTPRIKAELTSSAPACYALAISPDSKVCFSCCSDG-NIAVWDLHNQTLVRQFQ---- 613
Query: 259 NQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQV 143
TD C+ + S DG L+ G DNT+R W +
Sbjct: 614 -----GHTDGASCIDI--SNDGTKLWTGGLDNTVRSWDL 645
Score = 35.5 bits (78), Expect = 0.19
Identities = 37/137 (27%), Positives = 57/137 (41%), Gaps = 7/137 (5%)
Frame = -2
Query: 532 KINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDG------KHLHTLDHNDIITA 371
+IN L H + VT+S +GGK +WD++ L L+ ++ I +
Sbjct: 477 QINTLNHGEVVCAVTISNPTRHVYTGGKGC-VKVWDISHPGNKSPVSQLDCLNRDNYIRS 535
Query: 370 LCFSPNRYWLCAAFGPS-IKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDG 194
P+ L S + IWDL + P I + +S P C +LA S D
Sbjct: 536 CKLLPDGCTLIVGGEASTLSIWDLAAPT------PRIKAELTSSA---PACYALAISPDS 586
Query: 193 QTLFAGYSDNTIRVWQV 143
+ F+ SD I VW +
Sbjct: 587 KVCFSCCSDGNIAVWDL 603
>AL365190-2|CAI14977.1| 770|Homo sapiens transducin-like enhancer
of split 1 (E(sp1) homolog, Drosophila) protein.
Length = 770
Score = 58.4 bits (135), Expect = 2e-08
Identities = 36/133 (27%), Positives = 57/133 (42%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
G T+ +W+ LA I+ + S +C + + + + SC D + VW L N
Sbjct: 548 GGEASTLSIWD-LAAPTPRIKAELTSSAPACYALAISPDSKVCFSCCSDGNIAVWDLHNQ 606
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDIITALCFS 359
L GH+ + + +S DG+ +GG D WDL +G+ L D I +L +
Sbjct: 607 TLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVRSWDLREGRQLQQHDFTSQIFSLGYC 666
Query: 358 PNRYWLCAAFGPS 320
P WL S
Sbjct: 667 PTGEWLAVGMESS 679
Score = 46.4 bits (105), Expect = 1e-04
Identities = 41/159 (25%), Positives = 66/159 (41%), Gaps = 10/159 (6%)
Frame = -2
Query: 589 VSCGWDRTVKVWHLTNCKLK-----INHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWD 425
V G VKVW +++ K ++ L Y+ + + PDG GG+ +WD
Sbjct: 499 VYTGGKGCVKVWDISHPGNKSPVSQLDCLNRDNYIRSCKLLPDGCTLIVGGEASTLSIWD 558
Query: 424 L---NDGKHLHTLDHNDIITALCFSPNRY--WLCAAFGPSIKIWDLESKEMVEELRPEII 260
L AL SP+ + C + G +I +WDL ++ +V + +
Sbjct: 559 LAAPTPRIKAELTSSAPACYALAISPDSKVCFSCCSDG-NIAVWDLHNQTLVRQFQ---- 613
Query: 259 NQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQV 143
TD C+ + S DG L+ G DNT+R W +
Sbjct: 614 -----GHTDGASCIDI--SNDGTKLWTGGLDNTVRSWDL 645
Score = 35.5 bits (78), Expect = 0.19
Identities = 37/137 (27%), Positives = 57/137 (41%), Gaps = 7/137 (5%)
Frame = -2
Query: 532 KINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDG------KHLHTLDHNDIITA 371
+IN L H + VT+S +GGK +WD++ L L+ ++ I +
Sbjct: 477 QINTLNHGEVVCAVTISNPTRHVYTGGKGC-VKVWDISHPGNKSPVSQLDCLNRDNYIRS 535
Query: 370 LCFSPNRYWLCAAFGPS-IKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDG 194
P+ L S + IWDL + P I + +S P C +LA S D
Sbjct: 536 CKLLPDGCTLIVGGEASTLSIWDLAAPT------PRIKAELTSSA---PACYALAISPDS 586
Query: 193 QTLFAGYSDNTIRVWQV 143
+ F+ SD I VW +
Sbjct: 587 KVCFSCCSDGNIAVWDL 603
>AL353682-1|CAI12595.1| 770|Homo sapiens transducin-like enhancer
of split 1 (E(sp1) homolog, Drosophila) protein.
Length = 770
Score = 58.4 bits (135), Expect = 2e-08
Identities = 36/133 (27%), Positives = 57/133 (42%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
G T+ +W+ LA I+ + S +C + + + + SC D + VW L N
Sbjct: 548 GGEASTLSIWD-LAAPTPRIKAELTSSAPACYALAISPDSKVCFSCCSDGNIAVWDLHNQ 606
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDIITALCFS 359
L GH+ + + +S DG+ +GG D WDL +G+ L D I +L +
Sbjct: 607 TLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVRSWDLREGRQLQQHDFTSQIFSLGYC 666
Query: 358 PNRYWLCAAFGPS 320
P WL S
Sbjct: 667 PTGEWLAVGMESS 679
Score = 46.4 bits (105), Expect = 1e-04
Identities = 41/159 (25%), Positives = 66/159 (41%), Gaps = 10/159 (6%)
Frame = -2
Query: 589 VSCGWDRTVKVWHLTNCKLK-----INHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWD 425
V G VKVW +++ K ++ L Y+ + + PDG GG+ +WD
Sbjct: 499 VYTGGKGCVKVWDISHPGNKSPVSQLDCLNRDNYIRSCKLLPDGCTLIVGGEASTLSIWD 558
Query: 424 L---NDGKHLHTLDHNDIITALCFSPNRY--WLCAAFGPSIKIWDLESKEMVEELRPEII 260
L AL SP+ + C + G +I +WDL ++ +V + +
Sbjct: 559 LAAPTPRIKAELTSSAPACYALAISPDSKVCFSCCSDG-NIAVWDLHNQTLVRQFQ---- 613
Query: 259 NQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQV 143
TD C+ + S DG L+ G DNT+R W +
Sbjct: 614 -----GHTDGASCIDI--SNDGTKLWTGGLDNTVRSWDL 645
Score = 35.5 bits (78), Expect = 0.19
Identities = 37/137 (27%), Positives = 57/137 (41%), Gaps = 7/137 (5%)
Frame = -2
Query: 532 KINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDG------KHLHTLDHNDIITA 371
+IN L H + VT+S +GGK +WD++ L L+ ++ I +
Sbjct: 477 QINTLNHGEVVCAVTISNPTRHVYTGGKGC-VKVWDISHPGNKSPVSQLDCLNRDNYIRS 535
Query: 370 LCFSPNRYWLCAAFGPS-IKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDG 194
P+ L S + IWDL + P I + +S P C +LA S D
Sbjct: 536 CKLLPDGCTLIVGGEASTLSIWDLAAPT------PRIKAELTSSA---PACYALAISPDS 586
Query: 193 QTLFAGYSDNTIRVWQV 143
+ F+ SD I VW +
Sbjct: 587 KVCFSCCSDGNIAVWDL 603
>AL121993-4|CAI22739.1| 943|Homo sapiens WD repeat domain 3 protein.
Length = 943
Score = 58.4 bits (135), Expect = 2e-08
Identities = 44/165 (26%), Positives = 74/165 (44%), Gaps = 2/165 (1%)
Frame = -2
Query: 634 VSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASG 455
V CV +SPN ++ D TVK++++ K ++ GH + + +S DG+L A+G
Sbjct: 552 VLCVSYSPNQK--LLAVSLLDCTVKIFYVDTLKFFLSLYGHKLPVICMDISHDGALIATG 609
Query: 454 GKDMKAMLWDLNDGK-HLHTLDHNDIITALCFSPNRY-WLCAAFGPSIKIWDLESKEMVE 281
D +W L+ G H H+D + L F P + + A IK WD + E +
Sbjct: 610 SADRNVKIWGLDFGDCHKSLFAHDDSVMYLQFVPKSHLFFTAGKDHKIKQWDADKFEHI- 668
Query: 280 ELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQ 146
QT + + LA S G + + D ++R+W+
Sbjct: 669 ----------QTLEGHHQEIWCLAVSPSGDYVVSSSHDKSLRLWE 703
Score = 47.6 bits (108), Expect = 4e-05
Identities = 39/168 (23%), Positives = 80/168 (47%), Gaps = 3/168 (1%)
Frame = -2
Query: 634 VSCVRFSPNHANPIIVSCGW-DRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCAS 458
V+C+ SP+ + ++ G+ D +++++ L + + + GH + T+ G AS
Sbjct: 68 VTCLCPSPDGLH---LAVGYEDGSIRIFSLLSGEGNVTFNGHKAAITTLKYDQLGGRLAS 124
Query: 457 GGKDMKAMLWDLNDGKHLHTL-DHNDIIT-ALCFSPNRYWLCAAFGPSIKIWDLESKEMV 284
G KD ++WD+ + L+ L H D IT AL + + +K WDL+++
Sbjct: 125 GSKDTDIIVWDVINESGLYRLKGHKDAITQALFLREKNLLVTSGKDTMVKWWDLDTQHCF 184
Query: 283 EELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQVS 140
+ + + ++T+ L ++ + L G SD+ +RVW ++
Sbjct: 185 KTM---VGHRTEV--------WGLVLLSEEKRLITGASDSELRVWDIA 221
Score = 33.1 bits (72), Expect = 1.0
Identities = 41/199 (20%), Positives = 82/199 (41%), Gaps = 14/199 (7%)
Frame = -2
Query: 703 TIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKI 527
+IK+WN + +C T+ ++ C F P +I + ++++ L + L
Sbjct: 437 SIKIWNRSTLQCIRTMT----CEYALCSFFVPGDRQVVIGTK--TGKLQLYDLASGNLLE 490
Query: 526 NHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLN------------DGKHLHTLDHND 383
H G L ++++SPD +GG D WD K TL ++
Sbjct: 491 TIDAHDGALWSMSLSPDQRGFVTGGADKSVKFWDFELVKDENSTQKRLSVKQTRTLQLDE 550
Query: 382 IITALCFSPNRYWLCAA-FGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAW 206
+ + +SPN+ L + ++KI+ +++ + L + P C+ +
Sbjct: 551 DVLCVSYSPNQKLLAVSLLDCTVKIFYVDTLKFFLSLYGHKL---------PVICMDI-- 599
Query: 205 STDGQTLFAGYSDNTIRVW 149
S DG + G +D +++W
Sbjct: 600 SHDGALIATGSADRNVKIW 618
>AF501885-1|AAM15921.1| 353|Homo sapiens guanine nucleotide binding
protein beta 5 protein.
Length = 353
Score = 58.4 bits (135), Expect = 2e-08
Identities = 47/177 (26%), Positives = 86/177 (48%), Gaps = 4/177 (2%)
Frame = -2
Query: 646 HSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPD--G 473
H++++S F+ N I+ + G D T +W + + +L + GH + + ++P G
Sbjct: 152 HTNYLSACSFT-NSDMQILTASG-DGTCALWDVESGQLLQSFHGHGADVLCLDLAPSETG 209
Query: 472 SLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALCFSPNR-YWLCAAFGPSIKIWDLE 299
+ SGG D KAM+WD+ G+ + + H I ++ + P+ + + + +++DL
Sbjct: 210 NTFVSGGCDKKAMVWDMRSGQCVQAFETHESDINSVRYYPSGDAFASGSDDATCRLYDLR 269
Query: 298 SKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQVSISAR 128
+ V E I +S + +S G+ LFAGY+D TI VW V +R
Sbjct: 270 ADREVAIYSKESIIFGASS---------VDFSLSGRLLFAGYNDYTINVWDVLKGSR 317
Score = 56.4 bits (130), Expect = 1e-07
Identities = 52/194 (26%), Positives = 79/194 (40%), Gaps = 5/194 (2%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQD-DGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
S D T LW+ E +Q GH V C+ +P+ VS G D+ VW + +
Sbjct: 172 SGDGTCALWDV--ESGQLLQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDMRSG 229
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDII---TAL 368
+ H +N+V P G ASG D L+DL + + II +++
Sbjct: 230 QCVQAFETHESDINSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYSKESIIFGASSV 289
Query: 367 CFSPNRYWLCAAFGP-SIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQ 191
FS + L A + +I +WD+ V L N+ T + P DG
Sbjct: 290 DFSLSGRLLFAGYNDYTINVWDVLKGSRVSILFGH-ENRVSTLRVSP----------DGT 338
Query: 190 TLFAGYSDNTIRVW 149
+G D+T+RVW
Sbjct: 339 AFCSGSWDHTLRVW 352
Score = 35.5 bits (78), Expect = 0.19
Identities = 28/99 (28%), Positives = 45/99 (45%), Gaps = 2/99 (2%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDW-VSCVRFSPNHANPIIVSCGW-DRTVKVWHLT 545
GS D T +L++ A+ + I + S V FS + ++ G+ D T+ VW +
Sbjct: 257 GSDDATCRLYDLRADREVAIYSKESIIFGASSVDFSLSGR---LLFAGYNDYTINVWDVL 313
Query: 544 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLW 428
GH ++T+ VSPDG+ SG D +W
Sbjct: 314 KGSRVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLRVW 352
>AF300650-1|AAG18444.1| 395|Homo sapiens guanine nucleotide binding
protein beta subunit 5L protein.
Length = 395
Score = 58.4 bits (135), Expect = 2e-08
Identities = 47/177 (26%), Positives = 86/177 (48%), Gaps = 4/177 (2%)
Frame = -2
Query: 646 HSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPD--G 473
H++++S F+ N I+ + G D T +W + + +L + GH + + ++P G
Sbjct: 194 HTNYLSACSFT-NSDMQILTASG-DGTCALWDVESGQLLQSFHGHGADVLCLDLAPSETG 251
Query: 472 SLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALCFSPNR-YWLCAAFGPSIKIWDLE 299
+ SGG D KAM+WD+ G+ + + H I ++ + P+ + + + +++DL
Sbjct: 252 NTFVSGGCDKKAMVWDMRSGQCVQAFETHESDINSVRYYPSGDAFASGSDDATCRLYDLR 311
Query: 298 SKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQVSISAR 128
+ V E I +S + +S G+ LFAGY+D TI VW V +R
Sbjct: 312 ADREVAIYSKESIIFGASS---------VDFSLSGRLLFAGYNDYTINVWDVLKGSR 359
Score = 56.4 bits (130), Expect = 1e-07
Identities = 52/194 (26%), Positives = 79/194 (40%), Gaps = 5/194 (2%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQD-DGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
S D T LW+ E +Q GH V C+ +P+ VS G D+ VW + +
Sbjct: 214 SGDGTCALWDV--ESGQLLQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDMRSG 271
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDII---TAL 368
+ H +N+V P G ASG D L+DL + + II +++
Sbjct: 272 QCVQAFETHESDINSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYSKESIIFGASSV 331
Query: 367 CFSPNRYWLCAAFGP-SIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQ 191
FS + L A + +I +WD+ V L N+ T + P DG
Sbjct: 332 DFSLSGRLLFAGYNDYTINVWDVLKGSRVSILFGH-ENRVSTLRVSP----------DGT 380
Query: 190 TLFAGYSDNTIRVW 149
+G D+T+RVW
Sbjct: 381 AFCSGSWDHTLRVW 394
Score = 35.5 bits (78), Expect = 0.19
Identities = 28/99 (28%), Positives = 45/99 (45%), Gaps = 2/99 (2%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDW-VSCVRFSPNHANPIIVSCGW-DRTVKVWHLT 545
GS D T +L++ A+ + I + S V FS + ++ G+ D T+ VW +
Sbjct: 299 GSDDATCRLYDLRADREVAIYSKESIIFGASSVDFSLSGR---LLFAGYNDYTINVWDVL 355
Query: 544 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLW 428
GH ++T+ VSPDG+ SG D +W
Sbjct: 356 KGSRVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLRVW 394
>AF083217-1|AAD45865.1| 943|Homo sapiens WD repeat protein WDR3
protein.
Length = 943
Score = 58.4 bits (135), Expect = 2e-08
Identities = 44/165 (26%), Positives = 74/165 (44%), Gaps = 2/165 (1%)
Frame = -2
Query: 634 VSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASG 455
V CV +SPN ++ D TVK++++ K ++ GH + + +S DG+L A+G
Sbjct: 552 VLCVSYSPNQK--LLAVSLLDCTVKIFYVDTLKFFLSLYGHKLPVICMDISHDGALIATG 609
Query: 454 GKDMKAMLWDLNDGK-HLHTLDHNDIITALCFSPNRY-WLCAAFGPSIKIWDLESKEMVE 281
D +W L+ G H H+D + L F P + + A IK WD + E +
Sbjct: 610 SADRNVKIWGLDFGDCHKSLFAHDDSVMYLQFVPKSHLFFTAGKDHKIKQWDADKFEHI- 668
Query: 280 ELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQ 146
QT + + LA S G + + D ++R+W+
Sbjct: 669 ----------QTLEGHHQEIWCLAVSPSGDYVVSSSHDKSLRLWE 703
Score = 47.6 bits (108), Expect = 4e-05
Identities = 39/168 (23%), Positives = 80/168 (47%), Gaps = 3/168 (1%)
Frame = -2
Query: 634 VSCVRFSPNHANPIIVSCGW-DRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCAS 458
V+C+ SP+ + ++ G+ D +++++ L + + + GH + T+ G AS
Sbjct: 68 VTCLCPSPDGLH---LAVGYEDGSIRIFSLLSGEGNVTFNGHKAAITTLKYDQLGGRLAS 124
Query: 457 GGKDMKAMLWDLNDGKHLHTL-DHNDIIT-ALCFSPNRYWLCAAFGPSIKIWDLESKEMV 284
G KD ++WD+ + L+ L H D IT AL + + +K WDL+++
Sbjct: 125 GSKDTDIIVWDVINESGLYRLKGHKDAITQALFLREKNLLVTSGKDTMVKWWDLDTQHCF 184
Query: 283 EELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQVS 140
+ + + ++T+ L ++ + L G SD+ +RVW ++
Sbjct: 185 KTM---VGHRTEV--------WGLVLLSEEKRLITGASDSELRVWDIA 221
Score = 33.1 bits (72), Expect = 1.0
Identities = 41/199 (20%), Positives = 82/199 (41%), Gaps = 14/199 (7%)
Frame = -2
Query: 703 TIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKI 527
+IK+WN + +C T+ ++ C F P +I + ++++ L + L
Sbjct: 437 SIKIWNRSTLQCIRTMT----CEYALCSFFVPGDRQVVIGTK--TGKLQLYDLASGNLLE 490
Query: 526 NHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLN------------DGKHLHTLDHND 383
H G L ++++SPD +GG D WD K TL ++
Sbjct: 491 TIDAHDGALWSMSLSPDQRGFVTGGADKSVKFWDFELVKDENSTQKRLSVKQTRTLQLDE 550
Query: 382 IITALCFSPNRYWLCAA-FGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAW 206
+ + +SPN+ L + ++KI+ +++ + L + P C+ +
Sbjct: 551 DVLCVSYSPNQKLLAVSLLDCTVKIFYVDTLKFFLSLYGHKL---------PVICMDI-- 599
Query: 205 STDGQTLFAGYSDNTIRVW 149
S DG + G +D +++W
Sbjct: 600 SHDGALIATGSADRNVKIW 618
>AF017656-1|AAC63826.1| 353|Homo sapiens G protein beta 5 subunit
protein.
Length = 353
Score = 58.4 bits (135), Expect = 2e-08
Identities = 47/177 (26%), Positives = 86/177 (48%), Gaps = 4/177 (2%)
Frame = -2
Query: 646 HSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPD--G 473
H++++S F+ N I+ + G D T +W + + +L + GH + + ++P G
Sbjct: 152 HTNYLSACSFT-NSDMQILTASG-DGTCALWDVESGQLLQSFHGHGADVLCLDLAPSETG 209
Query: 472 SLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALCFSPNR-YWLCAAFGPSIKIWDLE 299
+ SGG D KAM+WD+ G+ + + H I ++ + P+ + + + +++DL
Sbjct: 210 NTFVSGGCDKKAMVWDMRSGQCVQAFETHESDINSVRYYPSGDAFASGSDDATCRLYDLR 269
Query: 298 SKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQVSISAR 128
+ V E I +S + +S G+ LFAGY+D TI VW V +R
Sbjct: 270 ADREVAIYSKESIIFGASS---------VDFSLSGRLLFAGYNDYTINVWDVLKGSR 317
Score = 56.4 bits (130), Expect = 1e-07
Identities = 52/194 (26%), Positives = 79/194 (40%), Gaps = 5/194 (2%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQD-DGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
S D T LW+ E +Q GH V C+ +P+ VS G D+ VW + +
Sbjct: 172 SGDGTCALWDV--ESGQLLQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDMRSG 229
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDII---TAL 368
+ H +N+V P G ASG D L+DL + + II +++
Sbjct: 230 QCVQAFETHESDINSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYSKESIIFGASSV 289
Query: 367 CFSPNRYWLCAAFGP-SIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQ 191
FS + L A + +I +WD+ V L N+ T + P DG
Sbjct: 290 DFSLSGRLLFAGYNDYTINVWDVLKGSRVSILFGH-ENRVSTLRVSP----------DGT 338
Query: 190 TLFAGYSDNTIRVW 149
+G D+T+RVW
Sbjct: 339 AFCSGSWDHTLRVW 352
Score = 35.5 bits (78), Expect = 0.19
Identities = 28/99 (28%), Positives = 45/99 (45%), Gaps = 2/99 (2%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDW-VSCVRFSPNHANPIIVSCGW-DRTVKVWHLT 545
GS D T +L++ A+ + I + S V FS + ++ G+ D T+ VW +
Sbjct: 257 GSDDATCRLYDLRADREVAIYSKESIIFGASSVDFSLSGR---LLFAGYNDYTINVWDVL 313
Query: 544 NCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLW 428
GH ++T+ VSPDG+ SG D +W
Sbjct: 314 KGSRVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLRVW 352
>AB209201-1|BAD92438.1| 466|Homo sapiens WD repeat-containing
protein 3 variant protein.
Length = 466
Score = 58.4 bits (135), Expect = 2e-08
Identities = 44/165 (26%), Positives = 74/165 (44%), Gaps = 2/165 (1%)
Frame = -2
Query: 634 VSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASG 455
V CV +SPN ++ D TVK++++ K ++ GH + + +S DG+L A+G
Sbjct: 75 VLCVSYSPNQK--LLAVSLLDCTVKIFYVDTLKFFLSLYGHKLPVICMDISHDGALIATG 132
Query: 454 GKDMKAMLWDLNDGK-HLHTLDHNDIITALCFSPNRY-WLCAAFGPSIKIWDLESKEMVE 281
D +W L+ G H H+D + L F P + + A IK WD + E +
Sbjct: 133 SADRNVKIWGLDFGDCHKSLFAHDDSVMYLQFVPKSHLFFTAGKDHKIKQWDADKFEHI- 191
Query: 280 ELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQ 146
QT + + LA S G + + D ++R+W+
Sbjct: 192 ----------QTLEGHHQEIWCLAVSPSGDYVVSSSHDKSLRLWE 226
Score = 30.7 bits (66), Expect = 5.5
Identities = 29/135 (21%), Positives = 56/135 (41%), Gaps = 13/135 (9%)
Frame = -2
Query: 514 HSGYLNTVTVSPDGSLCASGGKDMKAMLWDLN------------DGKHLHTLDHNDIITA 371
H G L ++++SPD +GG D WD K TL ++ +
Sbjct: 18 HDGALWSMSLSPDQRGFVTGGADKSVKFWDFELVKDENRTQKRLSVKQTRTLQLDEDVLC 77
Query: 370 LCFSPNRYWLCAA-FGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDG 194
+ +SPN+ L + ++KI+ +++ + L + P C+ + S DG
Sbjct: 78 VSYSPNQKLLAVSLLDCTVKIFYVDTLKFFLSLYGHKL---------PVICMDI--SHDG 126
Query: 193 QTLFAGYSDNTIRVW 149
+ G +D +++W
Sbjct: 127 ALIATGSADRNVKIW 141
>M99439-1|AAA61195.1| 448|Homo sapiens transducin-like enhancer
protein protein.
Length = 448
Score = 58.0 bits (134), Expect = 3e-08
Identities = 35/126 (27%), Positives = 56/126 (44%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
G T+ +W+ LA I+ + S +C + + + + SC D + VW L N
Sbjct: 226 GGEASTLSIWD-LAAPTPRIKAELTSSAPACYALAISPDSKVCFSCCSDGNIAVWDLHNQ 284
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDIITALCFS 359
L GH+ + + +S DG+ +GG D WDL +G+ L D I +L +
Sbjct: 285 TLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVRSWDLREGRQLQQHDFTSQIFSLGYC 344
Query: 358 PNRYWL 341
P WL
Sbjct: 345 PTGEWL 350
Score = 46.8 bits (106), Expect = 8e-05
Identities = 41/159 (25%), Positives = 66/159 (41%), Gaps = 10/159 (6%)
Frame = -2
Query: 589 VSCGWDRTVKVWHLTNCKLK-----INHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWD 425
V G VKVW +++ K ++ L Y+ + + PDG GG+ +WD
Sbjct: 177 VYTGGKGAVKVWDISHPGNKSPVSQLDCLNRDNYIRSCRLLPDGRTLIVGGEASTLSIWD 236
Query: 424 L---NDGKHLHTLDHNDIITALCFSPNRY--WLCAAFGPSIKIWDLESKEMVEELRPEII 260
L AL SP+ + C + G +I +WDL ++ +V + +
Sbjct: 237 LAAPTPRIKAELTSSAPACYALAISPDSKVCFSCCSDG-NIAVWDLHNQTLVRQFQ---- 291
Query: 259 NQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQV 143
TD C+ + S DG L+ G DNT+R W +
Sbjct: 292 -----GHTDGASCIDI--SNDGTKLWTGGLDNTVRSWDL 323
Score = 37.1 bits (82), Expect = 0.063
Identities = 36/137 (26%), Positives = 58/137 (42%), Gaps = 7/137 (5%)
Frame = -2
Query: 532 KINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDG------KHLHTLDHNDIITA 371
+IN L H + VT+S +GGK +WD++ L L+ ++ I +
Sbjct: 155 QINTLNHGEVVCAVTISNPTRHVYTGGKGA-VKVWDISHPGNKSPVSQLDCLNRDNYIRS 213
Query: 370 LCFSPN-RYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDG 194
P+ R + ++ IWDL + P I + +S P C +LA S D
Sbjct: 214 CRLLPDGRTLIVGGEASTLSIWDLAAPT------PRIKAELTSSA---PACYALAISPDS 264
Query: 193 QTLFAGYSDNTIRVWQV 143
+ F+ SD I VW +
Sbjct: 265 KVCFSCCSDGNIAVWDL 281
Score = 34.3 bits (75), Expect = 0.45
Identities = 24/95 (25%), Positives = 50/95 (52%), Gaps = 4/95 (4%)
Frame = -2
Query: 412 KHLHTLDHNDIITALCFS-PNRYWLCAAFGPSIKIWDLE---SKEMVEELRPEIINQTQT 245
+ ++TL+H +++ A+ S P R+ G ++K+WD+ +K V +L + +N+
Sbjct: 154 RQINTLNHGEVVCAVTISNPTRHVYTGGKG-AVKVWDISHPGNKSPVSQL--DCLNRDNY 210
Query: 244 SKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQVS 140
++ C L DG+TL G +T+ +W ++
Sbjct: 211 IRS----CRLLP---DGRTLIVGGEASTLSIWDLA 238
>M99436-1|AAA61193.1| 743|Homo sapiens transducin-like enhancer
protein protein.
Length = 743
Score = 58.0 bits (134), Expect = 3e-08
Identities = 35/133 (26%), Positives = 57/133 (42%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
G T+ +W+ LA I+ + S +C + + + SC D + VW L N
Sbjct: 521 GGEASTLSIWD-LAAPTPRIKAELTSSAPACYALAVSPDAKVCFSCCSDGNIVVWDLQNQ 579
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDIITALCFS 359
+ GH+ + + +S G+ +GG D WDL +G+ L D + I + C
Sbjct: 580 TMVRQFQGHTDGASCIDISDYGTRLWTGGLDNTVRCWDLREGRQLQQHDFSSQIFSPCHC 639
Query: 358 PNRYWLCAAFGPS 320
PN+ WL S
Sbjct: 640 PNQDWLAVGMESS 652
Score = 42.3 bits (95), Expect = 0.002
Identities = 41/159 (25%), Positives = 64/159 (40%), Gaps = 10/159 (6%)
Frame = -2
Query: 589 VSCGWDRTVKVWHLTNCKLK-----INHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWD 425
V G VKVW + K ++ L Y+ + + PDG GG+ +WD
Sbjct: 472 VYTGGKGCVKVWDVGQPGAKTPVRQLDCLNRDNYIRSCKLLPDGRSLIVGGEASTLSIWD 531
Query: 424 L---NDGKHLHTLDHNDIITALCFSPNRY--WLCAAFGPSIKIWDLESKEMVEELRPEII 260
L AL SP+ + C + G +I +WDL+++ MV + +
Sbjct: 532 LAAPTPRIKAELTSSAPACYALAVSPDAKVCFSCCSDG-NIVVWDLQNQTMVRQFQ---- 586
Query: 259 NQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQV 143
TD C+ + S G L+ G DNT+R W +
Sbjct: 587 -----GHTDGASCIDI--SDYGTRLWTGGLDNTVRCWDL 618
Score = 34.7 bits (76), Expect = 0.34
Identities = 34/137 (24%), Positives = 58/137 (42%), Gaps = 7/137 (5%)
Frame = -2
Query: 532 KINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDG------KHLHTLDHNDIITA 371
+++ L H + VT+S +GGK +WD+ + L L+ ++ I +
Sbjct: 450 QLHTLAHGEVVCAVTISGSTQHVYTGGKGC-VKVWDVGQPGAKTPVRQLDCLNRDNYIRS 508
Query: 370 LCFSPN-RYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDG 194
P+ R + ++ IWDL + P I + +S P C +LA S D
Sbjct: 509 CKLLPDGRSLIVGGEASTLSIWDLAAPT------PRIKAELTSSA---PACYALAVSPDA 559
Query: 193 QTLFAGYSDNTIRVWQV 143
+ F+ SD I VW +
Sbjct: 560 KVCFSCCSDGNIVVWDL 576
Score = 31.9 bits (69), Expect = 2.4
Identities = 20/92 (21%), Positives = 43/92 (46%), Gaps = 1/92 (1%)
Frame = -2
Query: 412 KHLHTLDHNDIITALCFSPNRYWLCAAFGPSIKIWDLESKEMVEELRP-EIINQTQTSKT 236
+ LHTL H +++ A+ S + + +K+WD+ +R + +N+ ++
Sbjct: 449 RQLHTLAHGEVVCAVTISGSTQHVYTGGKGCVKVWDVGQPGAKTPVRQLDCLNRDNYIRS 508
Query: 235 DPPQCLSLAWSTDGQTLFAGYSDNTIRVWQVS 140
C L DG++L G +T+ +W ++
Sbjct: 509 ----CKLL---PDGRSLIVGGEASTLSIWDLA 533
>BC059405-1|AAH59405.2| 805|Homo sapiens TLE4 protein protein.
Length = 805
Score = 58.0 bits (134), Expect = 3e-08
Identities = 35/126 (27%), Positives = 56/126 (44%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
G T+ +W+ LA I+ + S +C + + + + SC D + VW L N
Sbjct: 583 GGEASTLSIWD-LAAPTPRIKAELTSSAPACYALAISPDSKVCFSCCSDGNIAVWDLHNQ 641
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDIITALCFS 359
L GH+ + + +S DG+ +GG D WDL +G+ L D I +L +
Sbjct: 642 TLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVRSWDLREGRQLQQHDFTSQIFSLGYC 701
Query: 358 PNRYWL 341
P WL
Sbjct: 702 PTGEWL 707
Score = 46.4 bits (105), Expect = 1e-04
Identities = 41/159 (25%), Positives = 66/159 (41%), Gaps = 10/159 (6%)
Frame = -2
Query: 589 VSCGWDRTVKVWHLTNCKLK-----INHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWD 425
V G VKVW +++ K ++ L Y+ + + PDG GG+ +WD
Sbjct: 534 VYTGGKGCVKVWDISHPGNKSPVSQLDCLNRDNYIRSCRLLPDGRTLIVGGEASTLSIWD 593
Query: 424 L---NDGKHLHTLDHNDIITALCFSPNRY--WLCAAFGPSIKIWDLESKEMVEELRPEII 260
L AL SP+ + C + G +I +WDL ++ +V + +
Sbjct: 594 LAAPTPRIKAELTSSAPACYALAISPDSKVCFSCCSDG-NIAVWDLHNQTLVRQFQ---- 648
Query: 259 NQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQV 143
TD C+ + S DG L+ G DNT+R W +
Sbjct: 649 -----GHTDGASCIDI--SNDGTKLWTGGLDNTVRSWDL 680
Score = 37.1 bits (82), Expect = 0.063
Identities = 36/137 (26%), Positives = 58/137 (42%), Gaps = 7/137 (5%)
Frame = -2
Query: 532 KINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDG------KHLHTLDHNDIITA 371
+IN L H + VT+S +GGK +WD++ L L+ ++ I +
Sbjct: 512 QINTLNHGEVVCAVTISNPTRHVYTGGKGC-VKVWDISHPGNKSPVSQLDCLNRDNYIRS 570
Query: 370 LCFSPN-RYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDG 194
P+ R + ++ IWDL + P I + +S P C +LA S D
Sbjct: 571 CRLLPDGRTLIVGGEASTLSIWDLAAPT------PRIKAELTSSA---PACYALAISPDS 621
Query: 193 QTLFAGYSDNTIRVWQV 143
+ F+ SD I VW +
Sbjct: 622 KVCFSCCSDGNIAVWDL 638
Score = 33.5 bits (73), Expect = 0.78
Identities = 24/95 (25%), Positives = 49/95 (51%), Gaps = 4/95 (4%)
Frame = -2
Query: 412 KHLHTLDHNDIITALCFS-PNRYWLCAAFGPSIKIWDLE---SKEMVEELRPEIINQTQT 245
+ ++TL+H +++ A+ S P R+ G +K+WD+ +K V +L + +N+
Sbjct: 511 RQINTLNHGEVVCAVTISNPTRHVYTGGKG-CVKVWDISHPGNKSPVSQL--DCLNRDNY 567
Query: 244 SKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQVS 140
++ C L DG+TL G +T+ +W ++
Sbjct: 568 IRS----CRLLP---DGRTLIVGGEASTLSIWDLA 595
>BC045650-1|AAH45650.1| 704|Homo sapiens TLE4 protein protein.
Length = 704
Score = 58.0 bits (134), Expect = 3e-08
Identities = 35/126 (27%), Positives = 56/126 (44%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
G T+ +W+ LA I+ + S +C + + + + SC D + VW L N
Sbjct: 482 GGEASTLSIWD-LAAPTPRIKAELTSSAPACYALAISPDSKVCFSCCSDGNIAVWDLHNQ 540
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDIITALCFS 359
L GH+ + + +S DG+ +GG D WDL +G+ L D I +L +
Sbjct: 541 TLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVRSWDLREGRQLQQHDFTSQIFSLGYC 600
Query: 358 PNRYWL 341
P WL
Sbjct: 601 PTGEWL 606
Score = 46.4 bits (105), Expect = 1e-04
Identities = 41/159 (25%), Positives = 66/159 (41%), Gaps = 10/159 (6%)
Frame = -2
Query: 589 VSCGWDRTVKVWHLTNCKLK-----INHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWD 425
V G VKVW +++ K ++ L Y+ + + PDG GG+ +WD
Sbjct: 433 VYTGGKGCVKVWDISHPGNKSPVSQLDCLNRDNYIRSCRLLPDGRTLIVGGEASTLSIWD 492
Query: 424 L---NDGKHLHTLDHNDIITALCFSPNRY--WLCAAFGPSIKIWDLESKEMVEELRPEII 260
L AL SP+ + C + G +I +WDL ++ +V + +
Sbjct: 493 LAAPTPRIKAELTSSAPACYALAISPDSKVCFSCCSDG-NIAVWDLHNQTLVRQFQ---- 547
Query: 259 NQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQV 143
TD C+ + S DG L+ G DNT+R W +
Sbjct: 548 -----GHTDGASCIDI--SNDGTKLWTGGLDNTVRSWDL 579
Score = 37.1 bits (82), Expect = 0.063
Identities = 36/137 (26%), Positives = 58/137 (42%), Gaps = 7/137 (5%)
Frame = -2
Query: 532 KINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDG------KHLHTLDHNDIITA 371
+IN L H + VT+S +GGK +WD++ L L+ ++ I +
Sbjct: 411 QINTLNHGEVVCAVTISNPTRHVYTGGKGC-VKVWDISHPGNKSPVSQLDCLNRDNYIRS 469
Query: 370 LCFSPN-RYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDG 194
P+ R + ++ IWDL + P I + +S P C +LA S D
Sbjct: 470 CRLLPDGRTLIVGGEASTLSIWDLAAPT------PRIKAELTSSA---PACYALAISPDS 520
Query: 193 QTLFAGYSDNTIRVWQV 143
+ F+ SD I VW +
Sbjct: 521 KVCFSCCSDGNIAVWDL 537
Score = 33.5 bits (73), Expect = 0.78
Identities = 24/95 (25%), Positives = 49/95 (51%), Gaps = 4/95 (4%)
Frame = -2
Query: 412 KHLHTLDHNDIITALCFS-PNRYWLCAAFGPSIKIWDLE---SKEMVEELRPEIINQTQT 245
+ ++TL+H +++ A+ S P R+ G +K+WD+ +K V +L + +N+
Sbjct: 410 RQINTLNHGEVVCAVTISNPTRHVYTGGKG-CVKVWDISHPGNKSPVSQL--DCLNRDNY 466
Query: 244 SKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQVS 140
++ C L DG+TL G +T+ +W ++
Sbjct: 467 IRS----CRLLP---DGRTLIVGGEASTLSIWDLA 494
>AL445252-3|CAI13644.1| 764|Homo sapiens transducin-like enhancer
of split 4 (E(sp1) homolog, Drosophila) protein.
Length = 764
Score = 58.0 bits (134), Expect = 3e-08
Identities = 35/126 (27%), Positives = 56/126 (44%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
G T+ +W+ LA I+ + S +C + + + + SC D + VW L N
Sbjct: 542 GGEASTLSIWD-LAAPTPRIKAELTSSAPACYALAISPDSKVCFSCCSDGNIAVWDLHNQ 600
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDIITALCFS 359
L GH+ + + +S DG+ +GG D WDL +G+ L D I +L +
Sbjct: 601 TLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVRSWDLREGRQLQQHDFTSQIFSLGYC 660
Query: 358 PNRYWL 341
P WL
Sbjct: 661 PTGEWL 666
Score = 46.4 bits (105), Expect = 1e-04
Identities = 41/159 (25%), Positives = 66/159 (41%), Gaps = 10/159 (6%)
Frame = -2
Query: 589 VSCGWDRTVKVWHLTNCKLK-----INHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWD 425
V G VKVW +++ K ++ L Y+ + + PDG GG+ +WD
Sbjct: 493 VYTGGKGCVKVWDISHPGNKSPVSQLDCLNRDNYIRSCRLLPDGRTLIVGGEASTLSIWD 552
Query: 424 L---NDGKHLHTLDHNDIITALCFSPNRY--WLCAAFGPSIKIWDLESKEMVEELRPEII 260
L AL SP+ + C + G +I +WDL ++ +V + +
Sbjct: 553 LAAPTPRIKAELTSSAPACYALAISPDSKVCFSCCSDG-NIAVWDLHNQTLVRQFQ---- 607
Query: 259 NQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQV 143
TD C+ + S DG L+ G DNT+R W +
Sbjct: 608 -----GHTDGASCIDI--SNDGTKLWTGGLDNTVRSWDL 639
Score = 37.1 bits (82), Expect = 0.063
Identities = 36/137 (26%), Positives = 58/137 (42%), Gaps = 7/137 (5%)
Frame = -2
Query: 532 KINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDG------KHLHTLDHNDIITA 371
+IN L H + VT+S +GGK +WD++ L L+ ++ I +
Sbjct: 471 QINTLNHGEVVCAVTISNPTRHVYTGGKGC-VKVWDISHPGNKSPVSQLDCLNRDNYIRS 529
Query: 370 LCFSPN-RYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDG 194
P+ R + ++ IWDL + P I + +S P C +LA S D
Sbjct: 530 CRLLPDGRTLIVGGEASTLSIWDLAAPT------PRIKAELTSSA---PACYALAISPDS 580
Query: 193 QTLFAGYSDNTIRVWQV 143
+ F+ SD I VW +
Sbjct: 581 KVCFSCCSDGNIAVWDL 597
Score = 33.5 bits (73), Expect = 0.78
Identities = 24/95 (25%), Positives = 49/95 (51%), Gaps = 4/95 (4%)
Frame = -2
Query: 412 KHLHTLDHNDIITALCFS-PNRYWLCAAFGPSIKIWDLE---SKEMVEELRPEIINQTQT 245
+ ++TL+H +++ A+ S P R+ G +K+WD+ +K V +L + +N+
Sbjct: 470 RQINTLNHGEVVCAVTISNPTRHVYTGGKG-CVKVWDISHPGNKSPVSQL--DCLNRDNY 526
Query: 244 SKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQVS 140
++ C L DG+TL G +T+ +W ++
Sbjct: 527 IRS----CRLLP---DGRTLIVGGEASTLSIWDLA 554
>AL358975-3|CAI13734.1| 764|Homo sapiens transducin-like enhancer
of split 4 (E(sp1) homolog, Drosophila) protein.
Length = 764
Score = 58.0 bits (134), Expect = 3e-08
Identities = 35/126 (27%), Positives = 56/126 (44%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
G T+ +W+ LA I+ + S +C + + + + SC D + VW L N
Sbjct: 542 GGEASTLSIWD-LAAPTPRIKAELTSSAPACYALAISPDSKVCFSCCSDGNIAVWDLHNQ 600
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDIITALCFS 359
L GH+ + + +S DG+ +GG D WDL +G+ L D I +L +
Sbjct: 601 TLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVRSWDLREGRQLQQHDFTSQIFSLGYC 660
Query: 358 PNRYWL 341
P WL
Sbjct: 661 PTGEWL 666
Score = 46.4 bits (105), Expect = 1e-04
Identities = 41/159 (25%), Positives = 66/159 (41%), Gaps = 10/159 (6%)
Frame = -2
Query: 589 VSCGWDRTVKVWHLTNCKLK-----INHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWD 425
V G VKVW +++ K ++ L Y+ + + PDG GG+ +WD
Sbjct: 493 VYTGGKGCVKVWDISHPGNKSPVSQLDCLNRDNYIRSCRLLPDGRTLIVGGEASTLSIWD 552
Query: 424 L---NDGKHLHTLDHNDIITALCFSPNRY--WLCAAFGPSIKIWDLESKEMVEELRPEII 260
L AL SP+ + C + G +I +WDL ++ +V + +
Sbjct: 553 LAAPTPRIKAELTSSAPACYALAISPDSKVCFSCCSDG-NIAVWDLHNQTLVRQFQ---- 607
Query: 259 NQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQV 143
TD C+ + S DG L+ G DNT+R W +
Sbjct: 608 -----GHTDGASCIDI--SNDGTKLWTGGLDNTVRSWDL 639
Score = 37.1 bits (82), Expect = 0.063
Identities = 36/137 (26%), Positives = 58/137 (42%), Gaps = 7/137 (5%)
Frame = -2
Query: 532 KINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDG------KHLHTLDHNDIITA 371
+IN L H + VT+S +GGK +WD++ L L+ ++ I +
Sbjct: 471 QINTLNHGEVVCAVTISNPTRHVYTGGKGC-VKVWDISHPGNKSPVSQLDCLNRDNYIRS 529
Query: 370 LCFSPN-RYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDG 194
P+ R + ++ IWDL + P I + +S P C +LA S D
Sbjct: 530 CRLLPDGRTLIVGGEASTLSIWDLAAPT------PRIKAELTSSA---PACYALAISPDS 580
Query: 193 QTLFAGYSDNTIRVWQV 143
+ F+ SD I VW +
Sbjct: 581 KVCFSCCSDGNIAVWDL 597
Score = 33.5 bits (73), Expect = 0.78
Identities = 24/95 (25%), Positives = 49/95 (51%), Gaps = 4/95 (4%)
Frame = -2
Query: 412 KHLHTLDHNDIITALCFS-PNRYWLCAAFGPSIKIWDLE---SKEMVEELRPEIINQTQT 245
+ ++TL+H +++ A+ S P R+ G +K+WD+ +K V +L + +N+
Sbjct: 470 RQINTLNHGEVVCAVTISNPTRHVYTGGKG-CVKVWDISHPGNKSPVSQL--DCLNRDNY 526
Query: 244 SKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQVS 140
++ C L DG+TL G +T+ +W ++
Sbjct: 527 IRS----CRLLP---DGRTLIVGGEASTLSIWDLA 554
>AL353813-5|CAI41315.1| 764|Homo sapiens transducin-like enhancer
of split 4 (E(sp1) homolog, Drosophila) protein.
Length = 764
Score = 58.0 bits (134), Expect = 3e-08
Identities = 35/126 (27%), Positives = 56/126 (44%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
G T+ +W+ LA I+ + S +C + + + + SC D + VW L N
Sbjct: 542 GGEASTLSIWD-LAAPTPRIKAELTSSAPACYALAISPDSKVCFSCCSDGNIAVWDLHNQ 600
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDIITALCFS 359
L GH+ + + +S DG+ +GG D WDL +G+ L D I +L +
Sbjct: 601 TLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVRSWDLREGRQLQQHDFTSQIFSLGYC 660
Query: 358 PNRYWL 341
P WL
Sbjct: 661 PTGEWL 666
Score = 46.4 bits (105), Expect = 1e-04
Identities = 41/159 (25%), Positives = 66/159 (41%), Gaps = 10/159 (6%)
Frame = -2
Query: 589 VSCGWDRTVKVWHLTNCKLK-----INHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWD 425
V G VKVW +++ K ++ L Y+ + + PDG GG+ +WD
Sbjct: 493 VYTGGKGCVKVWDISHPGNKSPVSQLDCLNRDNYIRSCRLLPDGRTLIVGGEASTLSIWD 552
Query: 424 L---NDGKHLHTLDHNDIITALCFSPNRY--WLCAAFGPSIKIWDLESKEMVEELRPEII 260
L AL SP+ + C + G +I +WDL ++ +V + +
Sbjct: 553 LAAPTPRIKAELTSSAPACYALAISPDSKVCFSCCSDG-NIAVWDLHNQTLVRQFQ---- 607
Query: 259 NQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQV 143
TD C+ + S DG L+ G DNT+R W +
Sbjct: 608 -----GHTDGASCIDI--SNDGTKLWTGGLDNTVRSWDL 639
Score = 37.1 bits (82), Expect = 0.063
Identities = 36/137 (26%), Positives = 58/137 (42%), Gaps = 7/137 (5%)
Frame = -2
Query: 532 KINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDG------KHLHTLDHNDIITA 371
+IN L H + VT+S +GGK +WD++ L L+ ++ I +
Sbjct: 471 QINTLNHGEVVCAVTISNPTRHVYTGGKGC-VKVWDISHPGNKSPVSQLDCLNRDNYIRS 529
Query: 370 LCFSPN-RYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDG 194
P+ R + ++ IWDL + P I + +S P C +LA S D
Sbjct: 530 CRLLPDGRTLIVGGEASTLSIWDLAAPT------PRIKAELTSSA---PACYALAISPDS 580
Query: 193 QTLFAGYSDNTIRVWQV 143
+ F+ SD I VW +
Sbjct: 581 KVCFSCCSDGNIAVWDL 597
Score = 33.5 bits (73), Expect = 0.78
Identities = 24/95 (25%), Positives = 49/95 (51%), Gaps = 4/95 (4%)
Frame = -2
Query: 412 KHLHTLDHNDIITALCFS-PNRYWLCAAFGPSIKIWDLE---SKEMVEELRPEIINQTQT 245
+ ++TL+H +++ A+ S P R+ G +K+WD+ +K V +L + +N+
Sbjct: 470 RQINTLNHGEVVCAVTISNPTRHVYTGGKG-CVKVWDISHPGNKSPVSQL--DCLNRDNY 526
Query: 244 SKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQVS 140
++ C L DG+TL G +T+ +W ++
Sbjct: 527 IRS----CRLLP---DGRTLIVGGEASTLSIWDLA 554
>AJ243107-1|CAB56462.1| 1171|Homo sapiens apoptotic protease
activating factor-1 protein.
Length = 1171
Score = 58.0 bits (134), Expect = 3e-08
Identities = 44/152 (28%), Positives = 74/152 (48%), Gaps = 10/152 (6%)
Frame = -2
Query: 715 SRDKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
S D I++WN L +C + GH + V R N ++S +D TVKVW++
Sbjct: 987 SDDAEIQVWNWQLDKCIFL---RGHQETVKDFRLLKNSR---LLSWSFDGTVKVWNIITG 1040
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLH---------TLDHN 386
+ + + H G + + +S D + +S D A +W++++G+ LH H
Sbjct: 1041 NKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWNVSNGELLHLCAPLSEEGAATHG 1100
Query: 385 DIITALCFSPNRYWLCAAFGPSIKIWDLESKE 290
+T LCFSP+ L +A G IK W++ + E
Sbjct: 1101 GWVTDLCFSPDGKMLISA-GGYIKWWNVVTGE 1131
Score = 57.6 bits (133), Expect = 4e-08
Identities = 47/198 (23%), Positives = 80/198 (40%), Gaps = 8/198 (4%)
Frame = -2
Query: 715 SRDKTIKLWNTLA-ECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
S DK +K+WN++ E +T D HS+ V+C F+ + + ++ + D +K+W L
Sbjct: 684 SVDKKVKIWNSMTGELVHTY--DEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLNQK 741
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDIITALCFS 359
+ + GH+ +N SPD AS D LWD +++ L
Sbjct: 742 ECRNTMFGHTNSVNHCRFSPDDKPLASCSADGTLKLWDATSANERKSINVKQFFLNL-ED 800
Query: 358 PNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLS-LAW------ST 200
P S W + ++ + +I S++ C L+W S
Sbjct: 801 PQEDMEVIVKCCS---WSADGARIMVAAKNKIFLWNTDSRSKVADCRGHLSWVHGVMFSP 857
Query: 199 DGQTLFAGYSDNTIRVWQ 146
DG + D TIR+W+
Sbjct: 858 DGSSFLTSSDDQTIRLWE 875
Score = 51.6 bits (118), Expect = 3e-06
Identities = 39/146 (26%), Positives = 64/146 (43%), Gaps = 6/146 (4%)
Frame = -2
Query: 646 HSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSL 467
H+D V FS + I SCG D+T++V+ + + H + S D
Sbjct: 622 HTDAVYHACFSEDGQR--IASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRF 679
Query: 466 CASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALCFSPNRYWLCAAFGPS---IKIWDLE 299
A+ D K +W+ G+ +HT D H++ + F+ + + L A G S +K+WDL
Sbjct: 680 IATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLN 739
Query: 298 SKEMVEEL--RPEIINQTQTSKTDPP 227
KE + +N + S D P
Sbjct: 740 QKECRNTMFGHTNSVNHCRFSPDDKP 765
Score = 39.5 bits (88), Expect = 0.012
Identities = 41/153 (26%), Positives = 69/153 (45%), Gaps = 15/153 (9%)
Frame = -2
Query: 718 GSRDKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
GS D +KLW+ EC+ T+ GH++ V+ RFSP+ P+ SC D T+K+W T+
Sbjct: 727 GSSDCFLKLWDLNQKECRNTMF--GHTNSVNHCRFSPDD-KPL-ASCSADGTLKLWDATS 782
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSL---CASGGKD---------MKAMLWDLND-GKHLH 401
+ + +LN D + C S D K LW+ + K
Sbjct: 783 ANERKSINVKQFFLNLEDPQEDMEVIVKCCSWSADGARIMVAAKNKIFLWNTDSRSKVAD 842
Query: 400 TLDHNDIITALCFSPN-RYWLCAAFGPSIKIWD 305
H + + FSP+ +L ++ +I++W+
Sbjct: 843 CRGHLSWVHGVMFSPDGSSFLTSSDDQTIRLWE 875
>AB033087-1|BAA86575.1| 787|Homo sapiens KIAA1261 protein protein.
Length = 787
Score = 58.0 bits (134), Expect = 3e-08
Identities = 35/126 (27%), Positives = 56/126 (44%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
G T+ +W+ LA I+ + S +C + + + + SC D + VW L N
Sbjct: 565 GGEASTLSIWD-LAAPTPRIKAELTSSAPACYALAISPDSKVCFSCCSDGNIAVWDLHNQ 623
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDIITALCFS 359
L GH+ + + +S DG+ +GG D WDL +G+ L D I +L +
Sbjct: 624 TLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVRSWDLREGRQLQQHDFTSQIFSLGYC 683
Query: 358 PNRYWL 341
P WL
Sbjct: 684 PTGEWL 689
Score = 46.4 bits (105), Expect = 1e-04
Identities = 41/159 (25%), Positives = 66/159 (41%), Gaps = 10/159 (6%)
Frame = -2
Query: 589 VSCGWDRTVKVWHLTNCKLK-----INHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWD 425
V G VKVW +++ K ++ L Y+ + + PDG GG+ +WD
Sbjct: 516 VYTGGKGCVKVWDISHPGNKSPVSQLDCLNRDNYIRSCRLLPDGRTLIVGGEASTLSIWD 575
Query: 424 L---NDGKHLHTLDHNDIITALCFSPNRY--WLCAAFGPSIKIWDLESKEMVEELRPEII 260
L AL SP+ + C + G +I +WDL ++ +V + +
Sbjct: 576 LAAPTPRIKAELTSSAPACYALAISPDSKVCFSCCSDG-NIAVWDLHNQTLVRQFQ---- 630
Query: 259 NQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQV 143
TD C+ + S DG L+ G DNT+R W +
Sbjct: 631 -----GHTDGASCIDI--SNDGTKLWTGGLDNTVRSWDL 662
Score = 37.1 bits (82), Expect = 0.063
Identities = 36/137 (26%), Positives = 58/137 (42%), Gaps = 7/137 (5%)
Frame = -2
Query: 532 KINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDG------KHLHTLDHNDIITA 371
+IN L H + VT+S +GGK +WD++ L L+ ++ I +
Sbjct: 494 QINTLNHGEVVCAVTISNPTRHVYTGGKGC-VKVWDISHPGNKSPVSQLDCLNRDNYIRS 552
Query: 370 LCFSPN-RYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDG 194
P+ R + ++ IWDL + P I + +S P C +LA S D
Sbjct: 553 CRLLPDGRTLIVGGEASTLSIWDLAAPT------PRIKAELTSSA---PACYALAISPDS 603
Query: 193 QTLFAGYSDNTIRVWQV 143
+ F+ SD I VW +
Sbjct: 604 KVCFSCCSDGNIAVWDL 620
Score = 33.5 bits (73), Expect = 0.78
Identities = 24/95 (25%), Positives = 49/95 (51%), Gaps = 4/95 (4%)
Frame = -2
Query: 412 KHLHTLDHNDIITALCFS-PNRYWLCAAFGPSIKIWDLE---SKEMVEELRPEIINQTQT 245
+ ++TL+H +++ A+ S P R+ G +K+WD+ +K V +L + +N+
Sbjct: 493 RQINTLNHGEVVCAVTISNPTRHVYTGGKG-CVKVWDISHPGNKSPVSQL--DCLNRDNY 549
Query: 244 SKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQVS 140
++ C L DG+TL G +T+ +W ++
Sbjct: 550 IRS----CRLLP---DGRTLIVGGEASTLSIWDLA 577
>M99438-1|AAA61194.1| 772|Homo sapiens transducin-like enhancer
protein protein.
Length = 772
Score = 57.6 bits (133), Expect = 4e-08
Identities = 36/133 (27%), Positives = 56/133 (42%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
G T+ +W+ LA I+ + S +C + + + SC D + VW L N
Sbjct: 550 GGEGSTLTIWD-LASPTPRIKAELTSSAPACYALAISPDAKVCFSCCSDGNIAVWDLHNQ 608
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDIITALCFS 359
L GH+ + + +S DG+ +GG D WDL +G+ L D I +L +
Sbjct: 609 TLVRQFQGHTDGASCIDISHDGTKLWTGGLDNTVRSWDLREGRQLQQHDFTSQIFSLGYC 668
Query: 358 PNRYWLCAAFGPS 320
P WL S
Sbjct: 669 PTGEWLAVGMESS 681
Score = 46.4 bits (105), Expect = 1e-04
Identities = 40/159 (25%), Positives = 65/159 (40%), Gaps = 10/159 (6%)
Frame = -2
Query: 589 VSCGWDRTVKVWHLTNCKLK-----INHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWD 425
V G VK+W ++ K ++ L Y+ + + PDG GG+ +WD
Sbjct: 501 VYTGGKGCVKIWDISQPGSKSPISQLDCLNRDNYMRSCKLHPDGRTLIVGGEGSTLTIWD 560
Query: 424 LNDGK---HLHTLDHNDIITALCFSPNRY--WLCAAFGPSIKIWDLESKEMVEELRPEII 260
L AL SP+ + C + G +I +WDL ++ +V + +
Sbjct: 561 LASPTPRIKAELTSSAPACYALAISPDAKVCFSCCSDG-NIAVWDLHNQTLVRQFQ---- 615
Query: 259 NQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQV 143
TD C+ + S DG L+ G DNT+R W +
Sbjct: 616 -----GHTDGASCIDI--SHDGTKLWTGGLDNTVRSWDL 647
Score = 44.4 bits (100), Expect = 4e-04
Identities = 38/137 (27%), Positives = 60/137 (43%), Gaps = 7/137 (5%)
Frame = -2
Query: 532 KINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDG------KHLHTLDHNDIITA 371
+IN L H G + VT+S +GGK +WD++ L L+ ++ + +
Sbjct: 479 QINTLSHGGVVCAVTISNPSRHVYTGGKGC-VKIWDISQPGSKSPISQLDCLNRDNYMRS 537
Query: 370 LCFSPN-RYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDG 194
P+ R + G ++ IWDL S P I + +S P C +LA S D
Sbjct: 538 CKLHPDGRTLIVGGEGSTLTIWDLASPT------PRIKAELTSSA---PACYALAISPDA 588
Query: 193 QTLFAGYSDNTIRVWQV 143
+ F+ SD I VW +
Sbjct: 589 KVCFSCCSDGNIAVWDL 605
Score = 33.5 bits (73), Expect = 0.78
Identities = 24/95 (25%), Positives = 46/95 (48%), Gaps = 4/95 (4%)
Frame = -2
Query: 412 KHLHTLDHNDIITALCFS-PNRYWLCAAFGPSIKIWDLE---SKEMVEELRPEIINQTQT 245
+ ++TL H ++ A+ S P+R+ G +KIWD+ SK + +L + +N+
Sbjct: 478 RQINTLSHGGVVCAVTISNPSRHVYTGGKG-CVKIWDISQPGSKSPISQL--DCLNRDNY 534
Query: 244 SKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQVS 140
+ S DG+TL G +T+ +W ++
Sbjct: 535 MR-------SCKLHPDGRTLIVGGEGSTLTIWDLA 562
>AY583459-1|AAS90945.1| 764|Homo sapiens transducin-like enhancer
of split 3 splice variant 1 protein.
Length = 764
Score = 57.6 bits (133), Expect = 4e-08
Identities = 36/133 (27%), Positives = 56/133 (42%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
G T+ +W+ LA I+ + S +C + + + SC D + VW L N
Sbjct: 542 GGEASTLTIWD-LASPTPRIKAELTSSAPACYALAISPDAKVCFSCRSDGNIAVWDLHNQ 600
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDIITALCFS 359
L GH+ + + +S DG+ +GG D WDL +G+ L D I +L +
Sbjct: 601 TLVRQFQGHTDGASCIDISHDGTKLWTGGLDNTVRSWDLREGRQLQQHDFTSQIFSLGYC 660
Query: 358 PNRYWLCAAFGPS 320
P WL S
Sbjct: 661 PTGEWLAVGMESS 673
Score = 45.2 bits (102), Expect = 2e-04
Identities = 40/159 (25%), Positives = 65/159 (40%), Gaps = 10/159 (6%)
Frame = -2
Query: 589 VSCGWDRTVKVWHLTNCKLK-----INHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWD 425
V G VK+W ++ K ++ L Y+ + + PDG GG+ +WD
Sbjct: 493 VYTGGKGCVKIWDISQPGSKSPISQLDCLNRDNYIRSCKLLPDGRTLIVGGEASTLTIWD 552
Query: 424 LNDGK---HLHTLDHNDIITALCFSPNRY--WLCAAFGPSIKIWDLESKEMVEELRPEII 260
L AL SP+ + C + G +I +WDL ++ +V + +
Sbjct: 553 LASPTPRIKAELTSSAPACYALAISPDAKVCFSCRSDG-NIAVWDLHNQTLVRQFQ---- 607
Query: 259 NQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQV 143
TD C+ + S DG L+ G DNT+R W +
Sbjct: 608 -----GHTDGASCIDI--SHDGTKLWTGGLDNTVRSWDL 639
Score = 38.7 bits (86), Expect = 0.021
Identities = 37/137 (27%), Positives = 58/137 (42%), Gaps = 7/137 (5%)
Frame = -2
Query: 532 KINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDG------KHLHTLDHNDIITA 371
+IN L H + VT+S +GGK +WD++ L L+ ++ I +
Sbjct: 471 QINTLSHGEVVCAVTISNPTRHVYTGGKGC-VKIWDISQPGSKSPISQLDCLNRDNYIRS 529
Query: 370 LCFSPN-RYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDG 194
P+ R + ++ IWDL S P I + +S P C +LA S D
Sbjct: 530 CKLLPDGRTLIVGGEASTLTIWDLASPT------PRIKAELTSSA---PACYALAISPDA 580
Query: 193 QTLFAGYSDNTIRVWQV 143
+ F+ SD I VW +
Sbjct: 581 KVCFSCRSDGNIAVWDL 597
Score = 34.3 bits (75), Expect = 0.45
Identities = 25/95 (26%), Positives = 48/95 (50%), Gaps = 4/95 (4%)
Frame = -2
Query: 412 KHLHTLDHNDIITALCFS-PNRYWLCAAFGPSIKIWDLE---SKEMVEELRPEIINQTQT 245
+ ++TL H +++ A+ S P R+ G +KIWD+ SK + +L + +N+
Sbjct: 470 RQINTLSHGEVVCAVTISNPTRHVYTGGKG-CVKIWDISQPGSKSPISQL--DCLNRDNY 526
Query: 244 SKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQVS 140
++ C L DG+TL G +T+ +W ++
Sbjct: 527 IRS----CKLLP---DGRTLIVGGEASTLTIWDLA 554
>EF079890-1|ABN48555.1| 444|Homo sapiens ATG16 autophagy related
16-like protein 1 protein.
Length = 444
Score = 57.2 bits (132), Expect = 6e-08
Identities = 43/180 (23%), Positives = 79/180 (43%), Gaps = 6/180 (3%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAE-CKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
G D+ +KLW E C++ G + ++ + F + A +++ D ++W + +
Sbjct: 177 GGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEF--DSAGSYLLAASNDFASRIWTVDD 234
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL----DHNDII- 377
+L+ GHSG + + D + SG D LWDL + T+ NDI+
Sbjct: 235 YRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCIKTVFAGSSCNDIVC 294
Query: 376 TALCFSPNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTD 197
T C + F I+ WD+ S+ +V E+ E++ + +P + L+ S D
Sbjct: 295 TEQCV------MSGHFDKKIRFWDIRSESIVREM--ELLGKITALDLNPERTELLSCSRD 346
Score = 42.3 bits (95), Expect = 0.002
Identities = 48/193 (24%), Positives = 82/193 (42%), Gaps = 2/193 (1%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK 536
S D ++W T+ + + GHS V +F ++A IVS DRT+K+W L + K
Sbjct: 222 SNDFASRIW-TVDDYRLRHTLTGHSGKVLSAKFLLDNAR--IVSGSHDRTLKLWDLRS-K 277
Query: 535 LKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDIITALCFSP 356
+ I + N + + + SG D K WD+ + ++ ITAL +P
Sbjct: 278 VCIKTVFAGSSCNDIVCTEQCVM--SGHFDKKIRFWDIRSESIVREMELLGKITALDLNP 335
Query: 355 NRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDP--PQCLSLAWSTDGQTLF 182
R L + + V +LR I QT ++ + +S DG +
Sbjct: 336 ERTELLSCSRDDLL--------KVIDLRTNAIKQTFSAPGFKCGSDWTRVVFSPDGSYVA 387
Query: 181 AGYSDNTIRVWQV 143
AG ++ ++ +W V
Sbjct: 388 AGSAEGSLYIWSV 400
Score = 38.7 bits (86), Expect = 0.021
Identities = 36/128 (28%), Positives = 59/128 (46%), Gaps = 4/128 (3%)
Frame = -2
Query: 514 HSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGK--HLHTLD-HNDIITALCF-SPNRY 347
H G +N V SP L A+GG D + LW++ K +L N IT++ F S Y
Sbjct: 158 HDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGSY 217
Query: 346 WLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSD 167
L A+ + +IW V++ R + T T + + LS + D + +G D
Sbjct: 218 LLAASNDFASRIW------TVDDYR---LRHTLTGHSG--KVLSAKFLLDNARIVSGSHD 266
Query: 166 NTIRVWQV 143
T+++W +
Sbjct: 267 RTLKLWDL 274
Score = 37.5 bits (83), Expect = 0.048
Identities = 31/101 (30%), Positives = 47/101 (46%), Gaps = 5/101 (4%)
Frame = -2
Query: 715 SRDKTIKLWNTLAEC-KYTIQDDGH---SDWVSCVRFSPNHANPIIVSCGWDRTVKVWHL 548
SRD +K+ + K T G SDW V FSP+ + + + + ++ +W +
Sbjct: 344 SRDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTRVV-FSPDGS--YVAAGSAEGSLYIWSV 400
Query: 547 TNCKL-KINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLW 428
K+ K+ HS +N V SP GS S K KA+LW
Sbjct: 401 LTGKVEKVLSKQHSSSINAVAWSPSGSHVVSVDKGCKAVLW 441
Score = 34.7 bits (76), Expect = 0.34
Identities = 32/129 (24%), Positives = 55/129 (42%), Gaps = 7/129 (5%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
G DK I+ W+ +E +++ ++ + +P ++SC D +KV L
Sbjct: 302 GHFDKKIRFWDIRSES--IVREMELLGKITALDLNPERTE--LLSCSRDDLLKVIDLRTN 357
Query: 538 KLKINHLGHSGYL-----NTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL--DHNDI 380
+K G+ V SPDGS A+G + +W + GK L H+
Sbjct: 358 AIK-QTFSAPGFKCGSDWTRVVFSPDGSYVAAGSAEGSLYIWSVLTGKVEKVLSKQHSSS 416
Query: 379 ITALCFSPN 353
I A+ +SP+
Sbjct: 417 INAVAWSPS 425
>EF079889-1|ABN48554.1| 588|Homo sapiens ATG16 autophagy related
16-like protein 1 protein.
Length = 588
Score = 57.2 bits (132), Expect = 6e-08
Identities = 43/180 (23%), Positives = 79/180 (43%), Gaps = 6/180 (3%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAE-CKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
G D+ +KLW E C++ G + ++ + F + A +++ D ++W + +
Sbjct: 321 GGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEF--DSAGSYLLAASNDFASRIWTVDD 378
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL----DHNDII- 377
+L+ GHSG + + D + SG D LWDL + T+ NDI+
Sbjct: 379 YRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCIKTVFAGSSCNDIVC 438
Query: 376 TALCFSPNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTD 197
T C + F I+ WD+ S+ +V E+ E++ + +P + L+ S D
Sbjct: 439 TEQCV------MSGHFDKKIRFWDIRSESIVREM--ELLGKITALDLNPERTELLSCSRD 490
Score = 42.3 bits (95), Expect = 0.002
Identities = 48/193 (24%), Positives = 82/193 (42%), Gaps = 2/193 (1%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK 536
S D ++W T+ + + GHS V +F ++A IVS DRT+K+W L + K
Sbjct: 366 SNDFASRIW-TVDDYRLRHTLTGHSGKVLSAKFLLDNAR--IVSGSHDRTLKLWDLRS-K 421
Query: 535 LKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDIITALCFSP 356
+ I + N + + + SG D K WD+ + ++ ITAL +P
Sbjct: 422 VCIKTVFAGSSCNDIVCTEQCVM--SGHFDKKIRFWDIRSESIVREMELLGKITALDLNP 479
Query: 355 NRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDP--PQCLSLAWSTDGQTLF 182
R L + + V +LR I QT ++ + +S DG +
Sbjct: 480 ERTELLSCSRDDLL--------KVIDLRTNAIKQTFSAPGFKCGSDWTRVVFSPDGSYVA 531
Query: 181 AGYSDNTIRVWQV 143
AG ++ ++ +W V
Sbjct: 532 AGSAEGSLYIWSV 544
Score = 38.7 bits (86), Expect = 0.021
Identities = 36/128 (28%), Positives = 59/128 (46%), Gaps = 4/128 (3%)
Frame = -2
Query: 514 HSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGK--HLHTLD-HNDIITALCF-SPNRY 347
H G +N V SP L A+GG D + LW++ K +L N IT++ F S Y
Sbjct: 302 HDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGSY 361
Query: 346 WLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSD 167
L A+ + +IW V++ R + T T + + LS + D + +G D
Sbjct: 362 LLAASNDFASRIW------TVDDYR---LRHTLTGHSG--KVLSAKFLLDNARIVSGSHD 410
Query: 166 NTIRVWQV 143
T+++W +
Sbjct: 411 RTLKLWDL 418
Score = 37.5 bits (83), Expect = 0.048
Identities = 31/101 (30%), Positives = 47/101 (46%), Gaps = 5/101 (4%)
Frame = -2
Query: 715 SRDKTIKLWNTLAEC-KYTIQDDGH---SDWVSCVRFSPNHANPIIVSCGWDRTVKVWHL 548
SRD +K+ + K T G SDW V FSP+ + + + + ++ +W +
Sbjct: 488 SRDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTRVV-FSPDGS--YVAAGSAEGSLYIWSV 544
Query: 547 TNCKL-KINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLW 428
K+ K+ HS +N V SP GS S K KA+LW
Sbjct: 545 LTGKVEKVLSKQHSSSINAVAWSPSGSHVVSVDKGCKAVLW 585
Score = 34.7 bits (76), Expect = 0.34
Identities = 32/129 (24%), Positives = 55/129 (42%), Gaps = 7/129 (5%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
G DK I+ W+ +E +++ ++ + +P ++SC D +KV L
Sbjct: 446 GHFDKKIRFWDIRSES--IVREMELLGKITALDLNPERTE--LLSCSRDDLLKVIDLRTN 501
Query: 538 KLKINHLGHSGYL-----NTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL--DHNDI 380
+K G+ V SPDGS A+G + +W + GK L H+
Sbjct: 502 AIK-QTFSAPGFKCGSDWTRVVFSPDGSYVAAGSAEGSLYIWSVLTGKVEKVLSKQHSSS 560
Query: 379 ITALCFSPN 353
I A+ +SP+
Sbjct: 561 INAVAWSPS 569
>BC117337-1|AAI17338.1| 523|Homo sapiens ATG16L1 protein protein.
Length = 523
Score = 57.2 bits (132), Expect = 6e-08
Identities = 43/180 (23%), Positives = 79/180 (43%), Gaps = 6/180 (3%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAE-CKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
G D+ +KLW E C++ G + ++ + F + A +++ D ++W + +
Sbjct: 256 GGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEF--DSAGSYLLAASNDFASRIWTVDD 313
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL----DHNDII- 377
+L+ GHSG + + D + SG D LWDL + T+ NDI+
Sbjct: 314 YRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCIKTVFAGSSCNDIVC 373
Query: 376 TALCFSPNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTD 197
T C + F I+ WD+ S+ +V E+ E++ + +P + L+ S D
Sbjct: 374 TEQCV------MSGHFDKKIRFWDIRSESIVREM--ELLGKITALDLNPERTELLSCSRD 425
Score = 42.3 bits (95), Expect = 0.002
Identities = 48/193 (24%), Positives = 82/193 (42%), Gaps = 2/193 (1%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK 536
S D ++W T+ + + GHS V +F ++A IVS DRT+K+W L + K
Sbjct: 301 SNDFASRIW-TVDDYRLRHTLTGHSGKVLSAKFLLDNAR--IVSGSHDRTLKLWDLRS-K 356
Query: 535 LKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDIITALCFSP 356
+ I + N + + + SG D K WD+ + ++ ITAL +P
Sbjct: 357 VCIKTVFAGSSCNDIVCTEQCVM--SGHFDKKIRFWDIRSESIVREMELLGKITALDLNP 414
Query: 355 NRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDP--PQCLSLAWSTDGQTLF 182
R L + + V +LR I QT ++ + +S DG +
Sbjct: 415 ERTELLSCSRDDLL--------KVIDLRTNAIKQTFSAPGFKCGSDWTRVVFSPDGSYVA 466
Query: 181 AGYSDNTIRVWQV 143
AG ++ ++ +W V
Sbjct: 467 AGSAEGSLYIWSV 479
Score = 38.7 bits (86), Expect = 0.021
Identities = 36/128 (28%), Positives = 59/128 (46%), Gaps = 4/128 (3%)
Frame = -2
Query: 514 HSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGK--HLHTLD-HNDIITALCF-SPNRY 347
H G +N V SP L A+GG D + LW++ K +L N IT++ F S Y
Sbjct: 237 HDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGSY 296
Query: 346 WLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSD 167
L A+ + +IW V++ R + T T + + LS + D + +G D
Sbjct: 297 LLAASNDFASRIW------TVDDYR---LRHTLTGHSG--KVLSAKFLLDNARIVSGSHD 345
Query: 166 NTIRVWQV 143
T+++W +
Sbjct: 346 RTLKLWDL 353
Score = 37.5 bits (83), Expect = 0.048
Identities = 31/101 (30%), Positives = 47/101 (46%), Gaps = 5/101 (4%)
Frame = -2
Query: 715 SRDKTIKLWNTLAEC-KYTIQDDGH---SDWVSCVRFSPNHANPIIVSCGWDRTVKVWHL 548
SRD +K+ + K T G SDW V FSP+ + + + + ++ +W +
Sbjct: 423 SRDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTRVV-FSPDGS--YVAAGSAEGSLYIWSV 479
Query: 547 TNCKL-KINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLW 428
K+ K+ HS +N V SP GS S K KA+LW
Sbjct: 480 LTGKVEKVLSKQHSSSINAVAWSPSGSHVVSVDKGCKAVLW 520
Score = 34.7 bits (76), Expect = 0.34
Identities = 32/129 (24%), Positives = 55/129 (42%), Gaps = 7/129 (5%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
G DK I+ W+ +E +++ ++ + +P ++SC D +KV L
Sbjct: 381 GHFDKKIRFWDIRSES--IVREMELLGKITALDLNPERTE--LLSCSRDDLLKVIDLRTN 436
Query: 538 KLKINHLGHSGYL-----NTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL--DHNDI 380
+K G+ V SPDGS A+G + +W + GK L H+
Sbjct: 437 AIK-QTFSAPGFKCGSDWTRVVFSPDGSYVAAGSAEGSLYIWSVLTGKVEKVLSKQHSSS 495
Query: 379 ITALCFSPN 353
I A+ +SP+
Sbjct: 496 INAVAWSPS 504
>BC071846-1|AAH71846.1| 475|Homo sapiens ATG16L1 protein protein.
Length = 475
Score = 57.2 bits (132), Expect = 6e-08
Identities = 43/180 (23%), Positives = 79/180 (43%), Gaps = 6/180 (3%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAE-CKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
G D+ +KLW E C++ G + ++ + F + A +++ D ++W + +
Sbjct: 208 GGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEF--DSAGSYLLAASNDFASRIWTVDD 265
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL----DHNDII- 377
+L+ GHSG + + D + SG D LWDL + T+ NDI+
Sbjct: 266 YRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCIKTVFAGSSCNDIVC 325
Query: 376 TALCFSPNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTD 197
T C + F I+ WD+ S+ +V E+ E++ + +P + L+ S D
Sbjct: 326 TEQCV------MSGHFDKKIRFWDIRSESIVREM--ELLGKITALDLNPERTELLSCSRD 377
Score = 42.3 bits (95), Expect = 0.002
Identities = 48/193 (24%), Positives = 82/193 (42%), Gaps = 2/193 (1%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK 536
S D ++W T+ + + GHS V +F ++A IVS DRT+K+W L + K
Sbjct: 253 SNDFASRIW-TVDDYRLRHTLTGHSGKVLSAKFLLDNAR--IVSGSHDRTLKLWDLRS-K 308
Query: 535 LKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDIITALCFSP 356
+ I + N + + + SG D K WD+ + ++ ITAL +P
Sbjct: 309 VCIKTVFAGSSCNDIVCTEQCVM--SGHFDKKIRFWDIRSESIVREMELLGKITALDLNP 366
Query: 355 NRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDP--PQCLSLAWSTDGQTLF 182
R L + + V +LR I QT ++ + +S DG +
Sbjct: 367 ERTELLSCSRDDLL--------KVIDLRTNAIKQTFSAPGFKCGSDWTRVVFSPDGSYVA 418
Query: 181 AGYSDNTIRVWQV 143
AG ++ ++ +W V
Sbjct: 419 AGSAEGSLYIWSV 431
Score = 38.7 bits (86), Expect = 0.021
Identities = 36/128 (28%), Positives = 59/128 (46%), Gaps = 4/128 (3%)
Frame = -2
Query: 514 HSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGK--HLHTLD-HNDIITALCF-SPNRY 347
H G +N V SP L A+GG D + LW++ K +L N IT++ F S Y
Sbjct: 189 HDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGSY 248
Query: 346 WLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSD 167
L A+ + +IW V++ R + T T + + LS + D + +G D
Sbjct: 249 LLAASNDFASRIW------TVDDYR---LRHTLTGHSG--KVLSAKFLLDNARIVSGSHD 297
Query: 166 NTIRVWQV 143
T+++W +
Sbjct: 298 RTLKLWDL 305
Score = 37.5 bits (83), Expect = 0.048
Identities = 31/101 (30%), Positives = 47/101 (46%), Gaps = 5/101 (4%)
Frame = -2
Query: 715 SRDKTIKLWNTLAEC-KYTIQDDGH---SDWVSCVRFSPNHANPIIVSCGWDRTVKVWHL 548
SRD +K+ + K T G SDW V FSP+ + + + + ++ +W +
Sbjct: 375 SRDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTRVV-FSPDGS--YVAAGSAEGSLYIWSV 431
Query: 547 TNCKL-KINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLW 428
K+ K+ HS +N V SP GS S K KA+LW
Sbjct: 432 LTGKVEKVLSKQHSSSINAVAWSPSGSHVVSVDKGCKAVLW 472
Score = 34.7 bits (76), Expect = 0.34
Identities = 32/129 (24%), Positives = 55/129 (42%), Gaps = 7/129 (5%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
G DK I+ W+ +E +++ ++ + +P ++SC D +KV L
Sbjct: 333 GHFDKKIRFWDIRSES--IVREMELLGKITALDLNPERTE--LLSCSRDDLLKVIDLRTN 388
Query: 538 KLKINHLGHSGYL-----NTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL--DHNDI 380
+K G+ V SPDGS A+G + +W + GK L H+
Sbjct: 389 AIK-QTFSAPGFKCGSDWTRVVFSPDGSYVAAGSAEGSLYIWSVLTGKVEKVLSKQHSSS 447
Query: 379 ITALCFSPN 353
I A+ +SP+
Sbjct: 448 INAVAWSPS 456
>BC043247-1|AAH43247.1| 767|Homo sapiens TLE3 protein protein.
Length = 767
Score = 57.2 bits (132), Expect = 6e-08
Identities = 36/133 (27%), Positives = 56/133 (42%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
G T+ +W+ LA I+ + S +C + + + SC D + VW L N
Sbjct: 545 GGEASTLTIWD-LASPTPRIKAELTSSAPACYALAISPDAKVCFSCCSDGNIAVWDLHNQ 603
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDIITALCFS 359
L GH+ + + +S DG+ +GG D WDL +G+ L D I +L +
Sbjct: 604 TLVRQFQGHTDGASCIDISHDGTKLWTGGLDNTVRSWDLREGRQLQQHDFTSQIFSLGYC 663
Query: 358 PNRYWLCAAFGPS 320
P WL S
Sbjct: 664 PTGEWLAVGMESS 676
Score = 45.6 bits (103), Expect = 2e-04
Identities = 40/159 (25%), Positives = 65/159 (40%), Gaps = 10/159 (6%)
Frame = -2
Query: 589 VSCGWDRTVKVWHLTNCKLK-----INHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWD 425
V G VK+W ++ K ++ L Y+ + + PDG GG+ +WD
Sbjct: 496 VYTGGKGCVKIWDISQPGSKSPISQLDCLNRDNYIRSCKLLPDGRTLIVGGEASTLTIWD 555
Query: 424 LNDGK---HLHTLDHNDIITALCFSPNRY--WLCAAFGPSIKIWDLESKEMVEELRPEII 260
L AL SP+ + C + G +I +WDL ++ +V + +
Sbjct: 556 LASPTPRIKAELTSSAPACYALAISPDAKVCFSCCSDG-NIAVWDLHNQTLVRQFQ---- 610
Query: 259 NQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQV 143
TD C+ + S DG L+ G DNT+R W +
Sbjct: 611 -----GHTDGASCIDI--SHDGTKLWTGGLDNTVRSWDL 642
Score = 38.7 bits (86), Expect = 0.021
Identities = 37/137 (27%), Positives = 58/137 (42%), Gaps = 7/137 (5%)
Frame = -2
Query: 532 KINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDG------KHLHTLDHNDIITA 371
+IN L H + VT+S +GGK +WD++ L L+ ++ I +
Sbjct: 474 QINTLSHGEVVCAVTISNPTRHVYTGGKGC-VKIWDISQPGSKSPISQLDCLNRDNYIRS 532
Query: 370 LCFSPN-RYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDG 194
P+ R + ++ IWDL S P I + +S P C +LA S D
Sbjct: 533 CKLLPDGRTLIVGGEASTLTIWDLASPT------PRIKAELTSSA---PACYALAISPDA 583
Query: 193 QTLFAGYSDNTIRVWQV 143
+ F+ SD I VW +
Sbjct: 584 KVCFSCCSDGNIAVWDL 600
Score = 34.3 bits (75), Expect = 0.45
Identities = 25/95 (26%), Positives = 48/95 (50%), Gaps = 4/95 (4%)
Frame = -2
Query: 412 KHLHTLDHNDIITALCFS-PNRYWLCAAFGPSIKIWDLE---SKEMVEELRPEIINQTQT 245
+ ++TL H +++ A+ S P R+ G +KIWD+ SK + +L + +N+
Sbjct: 473 RQINTLSHGEVVCAVTISNPTRHVYTGGKG-CVKIWDISQPGSKSPISQL--DCLNRDNY 529
Query: 244 SKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQVS 140
++ C L DG+TL G +T+ +W ++
Sbjct: 530 IRS----CKLLP---DGRTLIVGGEASTLTIWDLA 557
>BC041831-1|AAH41831.1| 772|Homo sapiens TLE3 protein protein.
Length = 772
Score = 57.2 bits (132), Expect = 6e-08
Identities = 36/133 (27%), Positives = 56/133 (42%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
G T+ +W+ LA I+ + S +C + + + SC D + VW L N
Sbjct: 550 GGEASTLTIWD-LASPTPRIKAELTSSAPACYALAISPDAKVCFSCCSDGNIAVWDLHNQ 608
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDIITALCFS 359
L GH+ + + +S DG+ +GG D WDL +G+ L D I +L +
Sbjct: 609 TLVRQFQGHTDGASCIDISHDGTKLWTGGLDNTVRSWDLREGRQLQQHDFTSQIFSLGYC 668
Query: 358 PNRYWLCAAFGPS 320
P WL S
Sbjct: 669 PTGEWLAVGMESS 681
Score = 45.6 bits (103), Expect = 2e-04
Identities = 40/159 (25%), Positives = 65/159 (40%), Gaps = 10/159 (6%)
Frame = -2
Query: 589 VSCGWDRTVKVWHLTNCKLK-----INHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWD 425
V G VK+W ++ K ++ L Y+ + + PDG GG+ +WD
Sbjct: 501 VYTGGKGCVKIWDISQPGSKSPISQLDCLNRDNYIRSCKLLPDGRTLIVGGEASTLTIWD 560
Query: 424 LNDGK---HLHTLDHNDIITALCFSPNRY--WLCAAFGPSIKIWDLESKEMVEELRPEII 260
L AL SP+ + C + G +I +WDL ++ +V + +
Sbjct: 561 LASPTPRIKAELTSSAPACYALAISPDAKVCFSCCSDG-NIAVWDLHNQTLVRQFQ---- 615
Query: 259 NQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQV 143
TD C+ + S DG L+ G DNT+R W +
Sbjct: 616 -----GHTDGASCIDI--SHDGTKLWTGGLDNTVRSWDL 647
Score = 38.7 bits (86), Expect = 0.021
Identities = 37/137 (27%), Positives = 58/137 (42%), Gaps = 7/137 (5%)
Frame = -2
Query: 532 KINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDG------KHLHTLDHNDIITA 371
+IN L H + VT+S +GGK +WD++ L L+ ++ I +
Sbjct: 479 QINTLSHGEVVCAVTISNPTRHVYTGGKGC-VKIWDISQPGSKSPISQLDCLNRDNYIRS 537
Query: 370 LCFSPN-RYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDG 194
P+ R + ++ IWDL S P I + +S P C +LA S D
Sbjct: 538 CKLLPDGRTLIVGGEASTLTIWDLASPT------PRIKAELTSSA---PACYALAISPDA 588
Query: 193 QTLFAGYSDNTIRVWQV 143
+ F+ SD I VW +
Sbjct: 589 KVCFSCCSDGNIAVWDL 605
Score = 34.3 bits (75), Expect = 0.45
Identities = 25/95 (26%), Positives = 48/95 (50%), Gaps = 4/95 (4%)
Frame = -2
Query: 412 KHLHTLDHNDIITALCFS-PNRYWLCAAFGPSIKIWDLE---SKEMVEELRPEIINQTQT 245
+ ++TL H +++ A+ S P R+ G +KIWD+ SK + +L + +N+
Sbjct: 478 RQINTLSHGEVVCAVTISNPTRHVYTGGKG-CVKIWDISQPGSKSPISQL--DCLNRDNY 534
Query: 244 SKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQVS 140
++ C L DG+TL G +T+ +W ++
Sbjct: 535 IRS----CKLLP---DGRTLIVGGEASTLTIWDLA 562
>AY583460-1|AAS90946.1| 767|Homo sapiens transducin-like enhancer
of split 3 splice variant 2 protein.
Length = 767
Score = 57.2 bits (132), Expect = 6e-08
Identities = 36/133 (27%), Positives = 56/133 (42%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
G T+ +W+ LA I+ + S +C + + + SC D + VW L N
Sbjct: 545 GGEASTLTIWD-LASPTPRIKAELTSSAPACYALAISPDAKVCFSCCSDGNIAVWDLHNQ 603
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDIITALCFS 359
L GH+ + + +S DG+ +GG D WDL +G+ L D I +L +
Sbjct: 604 TLVRQFQGHTDGASCIDISHDGAKLWTGGLDNTVRSWDLREGRQLQQHDFTSQIFSLGYC 663
Query: 358 PNRYWLCAAFGPS 320
P WL S
Sbjct: 664 PTGEWLAVGMESS 676
Score = 45.6 bits (103), Expect = 2e-04
Identities = 40/159 (25%), Positives = 65/159 (40%), Gaps = 10/159 (6%)
Frame = -2
Query: 589 VSCGWDRTVKVWHLTNCKLK-----INHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWD 425
V G VK+W ++ K ++ L Y+ + + PDG GG+ +WD
Sbjct: 496 VYTGGKGCVKIWDISQPGSKSPISQLDCLNRDNYIRSCKLLPDGRTLIVGGEASTLTIWD 555
Query: 424 LNDGK---HLHTLDHNDIITALCFSPNRY--WLCAAFGPSIKIWDLESKEMVEELRPEII 260
L AL SP+ + C + G +I +WDL ++ +V + +
Sbjct: 556 LASPTPRIKAELTSSAPACYALAISPDAKVCFSCCSDG-NIAVWDLHNQTLVRQFQ---- 610
Query: 259 NQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQV 143
TD C+ + S DG L+ G DNT+R W +
Sbjct: 611 -----GHTDGASCIDI--SHDGAKLWTGGLDNTVRSWDL 642
Score = 36.7 bits (81), Expect = 0.084
Identities = 37/137 (27%), Positives = 57/137 (41%), Gaps = 7/137 (5%)
Frame = -2
Query: 532 KINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDG------KHLHTLDHNDIITA 371
+IN L H VT+S +GGK +WD++ L L+ ++ I +
Sbjct: 474 QINTLSHGEVGCAVTISNPTRHVYTGGKGC-VKIWDISQPGSKSPISQLDCLNRDNYIRS 532
Query: 370 LCFSPN-RYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDG 194
P+ R + ++ IWDL S P I + +S P C +LA S D
Sbjct: 533 CKLLPDGRTLIVGGEASTLTIWDLASPT------PRIKAELTSSA---PACYALAISPDA 583
Query: 193 QTLFAGYSDNTIRVWQV 143
+ F+ SD I VW +
Sbjct: 584 KVCFSCCSDGNIAVWDL 600
Score = 31.5 bits (68), Expect = 3.1
Identities = 25/95 (26%), Positives = 47/95 (49%), Gaps = 4/95 (4%)
Frame = -2
Query: 412 KHLHTLDHNDIITALCFS-PNRYWLCAAFGPSIKIWDLE---SKEMVEELRPEIINQTQT 245
+ ++TL H ++ A+ S P R+ G +KIWD+ SK + +L + +N+
Sbjct: 473 RQINTLSHGEVGCAVTISNPTRHVYTGGKG-CVKIWDISQPGSKSPISQL--DCLNRDNY 529
Query: 244 SKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQVS 140
++ C L DG+TL G +T+ +W ++
Sbjct: 530 IRS----CKLLP---DGRTLIVGGEASTLTIWDLA 557
>AY398617-1|AAR32130.1| 607|Homo sapiens APG16L beta protein.
Length = 607
Score = 57.2 bits (132), Expect = 6e-08
Identities = 43/180 (23%), Positives = 79/180 (43%), Gaps = 6/180 (3%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAE-CKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
G D+ +KLW E C++ G + ++ + F + A +++ D ++W + +
Sbjct: 340 GGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEF--DSAGSYLLAASNDFASRIWTVDD 397
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL----DHNDII- 377
+L+ GHSG + + D + SG D LWDL + T+ NDI+
Sbjct: 398 YRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCIKTVFAGSSCNDIVC 457
Query: 376 TALCFSPNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTD 197
T C + F I+ WD+ S+ +V E+ E++ + +P + L+ S D
Sbjct: 458 TEQCV------MSGHFDKKIRFWDIRSESIVREM--ELLGKITALDLNPERTELLSCSRD 509
Score = 42.3 bits (95), Expect = 0.002
Identities = 48/193 (24%), Positives = 82/193 (42%), Gaps = 2/193 (1%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK 536
S D ++W T+ + + GHS V +F ++A IVS DRT+K+W L + K
Sbjct: 385 SNDFASRIW-TVDDYRLRHTLTGHSGKVLSAKFLLDNAR--IVSGSHDRTLKLWDLRS-K 440
Query: 535 LKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDIITALCFSP 356
+ I + N + + + SG D K WD+ + ++ ITAL +P
Sbjct: 441 VCIKTVFAGSSCNDIVCTEQCVM--SGHFDKKIRFWDIRSESIVREMELLGKITALDLNP 498
Query: 355 NRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDP--PQCLSLAWSTDGQTLF 182
R L + + V +LR I QT ++ + +S DG +
Sbjct: 499 ERTELLSCSRDDLL--------KVIDLRTNAIKQTFSAPGFKCGSDWTRVVFSPDGSYVA 550
Query: 181 AGYSDNTIRVWQV 143
AG ++ ++ +W V
Sbjct: 551 AGSAEGSLYIWSV 563
Score = 38.7 bits (86), Expect = 0.021
Identities = 36/128 (28%), Positives = 59/128 (46%), Gaps = 4/128 (3%)
Frame = -2
Query: 514 HSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGK--HLHTLD-HNDIITALCF-SPNRY 347
H G +N V SP L A+GG D + LW++ K +L N IT++ F S Y
Sbjct: 321 HDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGSY 380
Query: 346 WLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSD 167
L A+ + +IW V++ R + T T + + LS + D + +G D
Sbjct: 381 LLAASNDFASRIW------TVDDYR---LRHTLTGHSG--KVLSAKFLLDNARIVSGSHD 429
Query: 166 NTIRVWQV 143
T+++W +
Sbjct: 430 RTLKLWDL 437
Score = 37.5 bits (83), Expect = 0.048
Identities = 31/101 (30%), Positives = 47/101 (46%), Gaps = 5/101 (4%)
Frame = -2
Query: 715 SRDKTIKLWNTLAEC-KYTIQDDGH---SDWVSCVRFSPNHANPIIVSCGWDRTVKVWHL 548
SRD +K+ + K T G SDW V FSP+ + + + + ++ +W +
Sbjct: 507 SRDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTRVV-FSPDGS--YVAAGSAEGSLYIWSV 563
Query: 547 TNCKL-KINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLW 428
K+ K+ HS +N V SP GS S K KA+LW
Sbjct: 564 LTGKVEKVLSKQHSSSINAVAWSPSGSHVVSVDKGCKAVLW 604
Score = 34.7 bits (76), Expect = 0.34
Identities = 32/129 (24%), Positives = 55/129 (42%), Gaps = 7/129 (5%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
G DK I+ W+ +E +++ ++ + +P ++SC D +KV L
Sbjct: 465 GHFDKKIRFWDIRSES--IVREMELLGKITALDLNPERTE--LLSCSRDDLLKVIDLRTN 520
Query: 538 KLKINHLGHSGYL-----NTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL--DHNDI 380
+K G+ V SPDGS A+G + +W + GK L H+
Sbjct: 521 AIK-QTFSAPGFKCGSDWTRVVFSPDGSYVAAGSAEGSLYIWSVLTGKVEKVLSKQHSSS 579
Query: 379 ITALCFSPN 353
I A+ +SP+
Sbjct: 580 INAVAWSPS 588
>AK027854-1|BAB55412.1| 504|Homo sapiens protein ( Homo sapiens
cDNA FLJ14948 fis, clone PLACE2000164, weakly similar to
TIPD PROTEIN. ).
Length = 504
Score = 57.2 bits (132), Expect = 6e-08
Identities = 43/180 (23%), Positives = 79/180 (43%), Gaps = 6/180 (3%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAE-CKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
G D+ +KLW E C++ G + ++ + F + A +++ D ++W + +
Sbjct: 237 GGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEF--DSAGSYLLAASNDFASRIWTVDD 294
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL----DHNDII- 377
+L+ GHSG + + D + SG D LWDL + T+ NDI+
Sbjct: 295 YRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCIKTVFAGSSCNDIVC 354
Query: 376 TALCFSPNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTD 197
T C + F I+ WD+ S+ +V E+ E++ + +P + L+ S D
Sbjct: 355 TEQCV------MSGHFDKKIRFWDIRSESIVREM--ELLGKITALDLNPERTELLSCSRD 406
Score = 43.6 bits (98), Expect = 7e-04
Identities = 49/193 (25%), Positives = 81/193 (41%), Gaps = 2/193 (1%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK 536
S D ++W T+ + + GHS V +F ++A IVS DRT+K+W L + K
Sbjct: 282 SNDFASRIW-TVDDYRLRHTLTGHSGKVLSAKFLLDNAR--IVSGSHDRTLKLWDLRS-K 337
Query: 535 LKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDIITALCFSP 356
+ I + N + + + SG D K WD+ + ++ ITAL +P
Sbjct: 338 VCIKTVFAGSSCNDIVCTEQCVM--SGHFDKKIRFWDIRSESIVREMELLGKITALDLNP 395
Query: 355 NRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQT--QTSKTDPPQCLSLAWSTDGQTLF 182
R L + + V +LR I QT T + +S DG +
Sbjct: 396 ERTELLSCSRDDLL--------KVIDLRTNAIKQTFSATGFKCGSDWTRVVFSPDGSYVA 447
Query: 181 AGYSDNTIRVWQV 143
AG ++ ++ +W V
Sbjct: 448 AGSAEGSLYIWSV 460
Score = 37.5 bits (83), Expect = 0.048
Identities = 31/101 (30%), Positives = 47/101 (46%), Gaps = 5/101 (4%)
Frame = -2
Query: 715 SRDKTIKLWNTLAEC-KYTIQDDGH---SDWVSCVRFSPNHANPIIVSCGWDRTVKVWHL 548
SRD +K+ + K T G SDW V FSP+ + + + + ++ +W +
Sbjct: 404 SRDDLLKVIDLRTNAIKQTFSATGFKCGSDWTRVV-FSPDGS--YVAAGSAEGSLYIWSV 460
Query: 547 TNCKL-KINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLW 428
K+ K+ HS +N V SP GS S K KA+LW
Sbjct: 461 LTGKVEKVLSKQHSSSINAVAWSPSGSHVVSVDKGCKAVLW 501
Score = 37.1 bits (82), Expect = 0.063
Identities = 35/128 (27%), Positives = 58/128 (45%), Gaps = 4/128 (3%)
Frame = -2
Query: 514 HSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGK--HLHTLD-HNDIITALCF-SPNRY 347
H G +N SP L A+GG D + LW++ K +L N IT++ F S Y
Sbjct: 218 HDGEVNAAQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGSY 277
Query: 346 WLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSD 167
L A+ + +IW V++ R + T T + + LS + D + +G D
Sbjct: 278 LLAASNDFASRIW------TVDDYR---LRHTLTGHSG--KVLSAKFLLDNARIVSGSHD 326
Query: 166 NTIRVWQV 143
T+++W +
Sbjct: 327 RTLKLWDL 334
Score = 35.5 bits (78), Expect = 0.19
Identities = 32/129 (24%), Positives = 56/129 (43%), Gaps = 7/129 (5%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
G DK I+ W+ +E +++ ++ + +P ++SC D +KV L
Sbjct: 362 GHFDKKIRFWDIRSES--IVREMELLGKITALDLNPERTE--LLSCSRDDLLKVIDLRTN 417
Query: 538 KLKINHLGHSGYL-----NTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL--DHNDI 380
+K +G+ V SPDGS A+G + +W + GK L H+
Sbjct: 418 AIK-QTFSATGFKCGSDWTRVVFSPDGSYVAAGSAEGSLYIWSVLTGKVEKVLSKQHSSS 476
Query: 379 ITALCFSPN 353
I A+ +SP+
Sbjct: 477 INAVAWSPS 485
>AJ243008-1|CAB55584.1| 1205|Homo sapiens apoptotic protease
activating factor 1 protein.
Length = 1205
Score = 57.2 bits (132), Expect = 6e-08
Identities = 47/198 (23%), Positives = 80/198 (40%), Gaps = 8/198 (4%)
Frame = -2
Query: 715 SRDKTIKLWNTLA-ECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
S DK +K+WN++ E +T D HS+ V+C F+ + + ++ + D +K+W L
Sbjct: 676 SVDKKVKIWNSMTGELVHTY--DEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLNQK 733
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDIITALCFS 359
+ + G + +N SPD L AS D LWD +++ L
Sbjct: 734 ECRNTMFGRTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKSINVKQFFLNL-ED 792
Query: 358 PNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLS-LAW------ST 200
P S W + ++ + +I S++ C L+W S
Sbjct: 793 PQEDMEVIVKCCS---WSADGARIMVAAKNKIFLWNTDSRSKVADCRGHLSWVHGVMFSP 849
Query: 199 DGQTLFAGYSDNTIRVWQ 146
DG + D TIR+W+
Sbjct: 850 DGSSFLTSSDDQTIRLWE 867
Score = 52.4 bits (120), Expect = 2e-06
Identities = 49/194 (25%), Positives = 84/194 (43%), Gaps = 3/194 (1%)
Frame = -2
Query: 715 SRDKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
S D I++WN L +C + GH + V R N ++S +D TVKVW++
Sbjct: 979 SDDAEIQVWNWQLDKCIFL---RGHQETVKDFRLLKNSR---LLSWSFDGTVKVWNIITG 1032
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCF 362
+ + + H G + + +S D + +S D A +W + LH L HN + F
Sbjct: 1033 NKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELRGHNGCVRCSAF 1092
Query: 361 SPNRYWLCAA-FGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTL 185
S + L I+IW++ + E++ P + + T L +S DG+ L
Sbjct: 1093 SVDSTLLATGDDNGEIRIWNVSNGELLHLCAP---LSEEGAATHGGWVTDLCFSPDGKML 1149
Query: 184 FAGYSDNTIRVWQV 143
+ + I+ W V
Sbjct: 1150 IS--AGGYIKWWNV 1161
Score = 51.6 bits (118), Expect = 3e-06
Identities = 41/155 (26%), Positives = 66/155 (42%), Gaps = 4/155 (2%)
Frame = -2
Query: 646 HSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSL 467
H+D V FS + I SCG D+T++V+ + + H + S D
Sbjct: 614 HTDAVYHACFSEDGQR--IASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRF 671
Query: 466 CASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALCFSPNRYWLCAAFGPS---IKIWDLE 299
A+ D K +W+ G+ +HT D H++ + F+ + + L A G S +K+WDL
Sbjct: 672 IATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLN 731
Query: 298 SKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDG 194
KE + N + P L + S DG
Sbjct: 732 QKECRNTMFGR-TNSVNHCRFSPDDKLLASCSADG 765
Score = 38.3 bits (85), Expect = 0.027
Identities = 39/153 (25%), Positives = 69/153 (45%), Gaps = 15/153 (9%)
Frame = -2
Query: 718 GSRDKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
GS D +KLW+ EC+ T+ G ++ V+ RFSP+ + ++ SC D T+K+W T+
Sbjct: 719 GSSDCFLKLWDLNQKECRNTMF--GRTNSVNHCRFSPD--DKLLASCSADGTLKLWDATS 774
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSL---CASGGKD---------MKAMLWDLND-GKHLH 401
+ + +LN D + C S D K LW+ + K
Sbjct: 775 ANERKSINVKQFFLNLEDPQEDMEVIVKCCSWSADGARIMVAAKNKIFLWNTDSRSKVAD 834
Query: 400 TLDHNDIITALCFSPN-RYWLCAAFGPSIKIWD 305
H + + FSP+ +L ++ +I++W+
Sbjct: 835 CRGHLSWVHGVMFSPDGSSFLTSSDDQTIRLWE 867
>AC013726-3|AAY14860.1| 523|Homo sapiens unknown protein.
Length = 523
Score = 57.2 bits (132), Expect = 6e-08
Identities = 43/180 (23%), Positives = 79/180 (43%), Gaps = 6/180 (3%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAE-CKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
G D+ +KLW E C++ G + ++ + F + A +++ D ++W + +
Sbjct: 256 GGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEF--DSAGSYLLAASNDFASRIWTVDD 313
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL----DHNDII- 377
+L+ GHSG + + D + SG D LWDL + T+ NDI+
Sbjct: 314 YRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCIKTVFAGSSCNDIVC 373
Query: 376 TALCFSPNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTD 197
T C + F I+ WD+ S+ +V E+ E++ + +P + L+ S D
Sbjct: 374 TEQCV------MSGHFDKKIRFWDIRSESIVREM--ELLGKITALDLNPERTELLSCSRD 425
Score = 42.3 bits (95), Expect = 0.002
Identities = 48/193 (24%), Positives = 82/193 (42%), Gaps = 2/193 (1%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK 536
S D ++W T+ + + GHS V +F ++A IVS DRT+K+W L + K
Sbjct: 301 SNDFASRIW-TVDDYRLRHTLTGHSGKVLSAKFLLDNAR--IVSGSHDRTLKLWDLRS-K 356
Query: 535 LKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDIITALCFSP 356
+ I + N + + + SG D K WD+ + ++ ITAL +P
Sbjct: 357 VCIKTVFAGSSCNDIVCTEQCVM--SGHFDKKIRFWDIRSESIVREMELLGKITALDLNP 414
Query: 355 NRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDP--PQCLSLAWSTDGQTLF 182
R L + + V +LR I QT ++ + +S DG +
Sbjct: 415 ERTELLSCSRDDLL--------KVIDLRTNAIKQTFSAPGFKCGSDWTRVVFSPDGSYVA 466
Query: 181 AGYSDNTIRVWQV 143
AG ++ ++ +W V
Sbjct: 467 AGSAEGSLYIWSV 479
Score = 38.7 bits (86), Expect = 0.021
Identities = 36/128 (28%), Positives = 59/128 (46%), Gaps = 4/128 (3%)
Frame = -2
Query: 514 HSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGK--HLHTLD-HNDIITALCF-SPNRY 347
H G +N V SP L A+GG D + LW++ K +L N IT++ F S Y
Sbjct: 237 HDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGSY 296
Query: 346 WLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSD 167
L A+ + +IW V++ R + T T + + LS + D + +G D
Sbjct: 297 LLAASNDFASRIW------TVDDYR---LRHTLTGHSG--KVLSAKFLLDNARIVSGSHD 345
Query: 166 NTIRVWQV 143
T+++W +
Sbjct: 346 RTLKLWDL 353
Score = 37.5 bits (83), Expect = 0.048
Identities = 31/101 (30%), Positives = 47/101 (46%), Gaps = 5/101 (4%)
Frame = -2
Query: 715 SRDKTIKLWNTLAEC-KYTIQDDGH---SDWVSCVRFSPNHANPIIVSCGWDRTVKVWHL 548
SRD +K+ + K T G SDW V FSP+ + + + + ++ +W +
Sbjct: 423 SRDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTRVV-FSPDGS--YVAAGSAEGSLYIWSV 479
Query: 547 TNCKL-KINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLW 428
K+ K+ HS +N V SP GS S K KA+LW
Sbjct: 480 LTGKVEKVLSKQHSSSINAVAWSPSGSHVVSVDKGCKAVLW 520
Score = 34.7 bits (76), Expect = 0.34
Identities = 32/129 (24%), Positives = 55/129 (42%), Gaps = 7/129 (5%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
G DK I+ W+ +E +++ ++ + +P ++SC D +KV L
Sbjct: 381 GHFDKKIRFWDIRSES--IVREMELLGKITALDLNPERTE--LLSCSRDDLLKVIDLRTN 436
Query: 538 KLKINHLGHSGYL-----NTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL--DHNDI 380
+K G+ V SPDGS A+G + +W + GK L H+
Sbjct: 437 AIK-QTFSAPGFKCGSDWTRVVFSPDGSYVAAGSAEGSLYIWSVLTGKVEKVLSKQHSSS 495
Query: 379 ITALCFSPN 353
I A+ +SP+
Sbjct: 496 INAVAWSPS 504
>AB046767-1|BAB13373.1| 863|Homo sapiens KIAA1547 protein protein.
Length = 863
Score = 57.2 bits (132), Expect = 6e-08
Identities = 36/133 (27%), Positives = 56/133 (42%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
G T+ +W+ LA I+ + S +C + + + SC D + VW L N
Sbjct: 641 GGEASTLTIWD-LASPTPRIKAELTSSAPACYALAISPDAKVCFSCCSDGNIAVWDLHNQ 699
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDIITALCFS 359
L GH+ + + +S DG+ +GG D WDL +G+ L D I +L +
Sbjct: 700 TLVRQFQGHTDGASCIDISHDGTKLWTGGLDNTVRSWDLREGRQLQQHDFTSQIFSLGYC 759
Query: 358 PNRYWLCAAFGPS 320
P WL S
Sbjct: 760 PTGEWLAVGMESS 772
Score = 45.6 bits (103), Expect = 2e-04
Identities = 40/159 (25%), Positives = 65/159 (40%), Gaps = 10/159 (6%)
Frame = -2
Query: 589 VSCGWDRTVKVWHLTNCKLK-----INHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWD 425
V G VK+W ++ K ++ L Y+ + + PDG GG+ +WD
Sbjct: 592 VYTGGKGCVKIWDISQPGSKSPISQLDCLNRDNYIRSCKLLPDGRTLIVGGEASTLTIWD 651
Query: 424 LNDGK---HLHTLDHNDIITALCFSPNRY--WLCAAFGPSIKIWDLESKEMVEELRPEII 260
L AL SP+ + C + G +I +WDL ++ +V + +
Sbjct: 652 LASPTPRIKAELTSSAPACYALAISPDAKVCFSCCSDG-NIAVWDLHNQTLVRQFQ---- 706
Query: 259 NQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQV 143
TD C+ + S DG L+ G DNT+R W +
Sbjct: 707 -----GHTDGASCIDI--SHDGTKLWTGGLDNTVRSWDL 738
Score = 38.7 bits (86), Expect = 0.021
Identities = 37/137 (27%), Positives = 58/137 (42%), Gaps = 7/137 (5%)
Frame = -2
Query: 532 KINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDG------KHLHTLDHNDIITA 371
+IN L H + VT+S +GGK +WD++ L L+ ++ I +
Sbjct: 570 QINTLSHGEVVCAVTISNPTRHVYTGGKGC-VKIWDISQPGSKSPISQLDCLNRDNYIRS 628
Query: 370 LCFSPN-RYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDG 194
P+ R + ++ IWDL S P I + +S P C +LA S D
Sbjct: 629 CKLLPDGRTLIVGGEASTLTIWDLASPT------PRIKAELTSSA---PACYALAISPDA 679
Query: 193 QTLFAGYSDNTIRVWQV 143
+ F+ SD I VW +
Sbjct: 680 KVCFSCCSDGNIAVWDL 696
Score = 34.3 bits (75), Expect = 0.45
Identities = 25/95 (26%), Positives = 48/95 (50%), Gaps = 4/95 (4%)
Frame = -2
Query: 412 KHLHTLDHNDIITALCFS-PNRYWLCAAFGPSIKIWDLE---SKEMVEELRPEIINQTQT 245
+ ++TL H +++ A+ S P R+ G +KIWD+ SK + +L + +N+
Sbjct: 569 RQINTLSHGEVVCAVTISNPTRHVYTGGKG-CVKIWDISQPGSKSPISQL--DCLNRDNY 625
Query: 244 SKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQVS 140
++ C L DG+TL G +T+ +W ++
Sbjct: 626 IRS----CKLLP---DGRTLIVGGEASTLTIWDLA 653
>EF560734-1|ABQ59044.1| 588|Homo sapiens ATG16L1 protein protein.
Length = 588
Score = 56.8 bits (131), Expect = 7e-08
Identities = 43/180 (23%), Positives = 79/180 (43%), Gaps = 6/180 (3%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAE-CKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
G D+ +KLW E C++ G + ++ + F + A +++ D ++W + +
Sbjct: 321 GGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEF--DGAGSYLLAASNDFASRIWTVDD 378
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL----DHNDII- 377
+L+ GHSG + + D + SG D LWDL + T+ NDI+
Sbjct: 379 YRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCIKTVFAGSSCNDIVC 438
Query: 376 TALCFSPNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTD 197
T C + F I+ WD+ S+ +V E+ E++ + +P + L+ S D
Sbjct: 439 TEQCV------MSGHFDKKIRFWDIRSESIVREM--ELLGKITALDLNPERTELLSCSRD 490
Score = 42.3 bits (95), Expect = 0.002
Identities = 48/193 (24%), Positives = 82/193 (42%), Gaps = 2/193 (1%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCK 536
S D ++W T+ + + GHS V +F ++A IVS DRT+K+W L + K
Sbjct: 366 SNDFASRIW-TVDDYRLRHTLTGHSGKVLSAKFLLDNAR--IVSGSHDRTLKLWDLRS-K 421
Query: 535 LKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDIITALCFSP 356
+ I + N + + + SG D K WD+ + ++ ITAL +P
Sbjct: 422 VCIKTVFAGSSCNDIVCTEQCVM--SGHFDKKIRFWDIRSESIVREMELLGKITALDLNP 479
Query: 355 NRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDP--PQCLSLAWSTDGQTLF 182
R L + + V +LR I QT ++ + +S DG +
Sbjct: 480 ERTELLSCSRDDLL--------KVIDLRTNAIKQTFSAPGFKCGSDWTRVVFSPDGSYVA 531
Query: 181 AGYSDNTIRVWQV 143
AG ++ ++ +W V
Sbjct: 532 AGSAEGSLYIWSV 544
Score = 37.5 bits (83), Expect = 0.048
Identities = 31/101 (30%), Positives = 47/101 (46%), Gaps = 5/101 (4%)
Frame = -2
Query: 715 SRDKTIKLWNTLAEC-KYTIQDDGH---SDWVSCVRFSPNHANPIIVSCGWDRTVKVWHL 548
SRD +K+ + K T G SDW V FSP+ + + + + ++ +W +
Sbjct: 488 SRDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTRVV-FSPDGS--YVAAGSAEGSLYIWSV 544
Query: 547 TNCKL-KINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLW 428
K+ K+ HS +N V SP GS S K KA+LW
Sbjct: 545 LTGKVEKVLSKQHSSSINAVAWSPSGSHVVSVDKGCKAVLW 585
Score = 37.1 bits (82), Expect = 0.063
Identities = 35/128 (27%), Positives = 58/128 (45%), Gaps = 4/128 (3%)
Frame = -2
Query: 514 HSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGK--HLHTLD-HNDIITALCF-SPNRY 347
H G +N V SP L A+GG D + LW++ K +L N IT++ F Y
Sbjct: 302 HDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDGAGSY 361
Query: 346 WLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSD 167
L A+ + +IW V++ R + T T + + LS + D + +G D
Sbjct: 362 LLAASNDFASRIW------TVDDYR---LRHTLTGHSG--KVLSAKFLLDNARIVSGSHD 410
Query: 166 NTIRVWQV 143
T+++W +
Sbjct: 411 RTLKLWDL 418
Score = 34.7 bits (76), Expect = 0.34
Identities = 32/129 (24%), Positives = 55/129 (42%), Gaps = 7/129 (5%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
G DK I+ W+ +E +++ ++ + +P ++SC D +KV L
Sbjct: 446 GHFDKKIRFWDIRSES--IVREMELLGKITALDLNPERTE--LLSCSRDDLLKVIDLRTN 501
Query: 538 KLKINHLGHSGYL-----NTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL--DHNDI 380
+K G+ V SPDGS A+G + +W + GK L H+
Sbjct: 502 AIK-QTFSAPGFKCGSDWTRVVFSPDGSYVAAGSAEGSLYIWSVLTGKVEKVLSKQHSSS 560
Query: 379 ITALCFSPN 353
I A+ +SP+
Sbjct: 561 INAVAWSPS 569
>BX679664-5|CAH71325.1| 891|Homo sapiens WD repeat domain 47 protein.
Length = 891
Score = 56.4 bits (130), Expect = 1e-07
Identities = 40/155 (25%), Positives = 74/155 (47%), Gaps = 6/155 (3%)
Frame = -2
Query: 595 IIVSCGWDRTVKVWHLT--NCKLKINHLGHS--GYLNTVTVSPDGSLCASGGKDMKAMLW 428
+I S D+TV+ W L +C + H + +V V P G L A+G +D ML+
Sbjct: 740 MIASGSQDKTVRFWDLRVPSCVRVVGTTFHGTGSAVASVAVDPSGRLLATGQEDSSCMLY 799
Query: 427 DLNDGKHLHTL-DHNDIITALCFSPN-RYWLCAAFGPSIKIWDLESKEMVEELRPEIINQ 254
D+ G+ + + H+ + ++ FSP Y L ++ IK+ DL+ ++ ++L ++ +
Sbjct: 800 DIRGGRMVQSYHPHSSDVRSVRFSPGAHYLLTGSYDMKIKVTDLQG-DLTKQLPIMVVGE 858
Query: 253 TQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVW 149
K QC W T + + +D T+ +W
Sbjct: 859 ---HKDKVIQC---RWHTQDLSFLSSSADRTVTLW 887
Score = 34.7 bits (76), Expect = 0.34
Identities = 20/100 (20%), Positives = 45/100 (45%), Gaps = 1/100 (1%)
Frame = -2
Query: 718 GSRDKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
GS+DKT++ W+ + C + H + + + + ++ + D + ++ +
Sbjct: 744 GSQDKTVRFWDLRVPSCVRVVGTTFHGTGSAVASVAVDPSGRLLATGQEDSSCMLYDIRG 803
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDL 422
++ ++ HS + +V SP +G DMK + DL
Sbjct: 804 GRMVQSYHPHSSDVRSVRFSPGAHYLLTGSYDMKIKVTDL 843
>BX679664-4|CAH71327.1| 919|Homo sapiens WD repeat domain 47 protein.
Length = 919
Score = 56.4 bits (130), Expect = 1e-07
Identities = 40/155 (25%), Positives = 74/155 (47%), Gaps = 6/155 (3%)
Frame = -2
Query: 595 IIVSCGWDRTVKVWHLT--NCKLKINHLGHS--GYLNTVTVSPDGSLCASGGKDMKAMLW 428
+I S D+TV+ W L +C + H + +V V P G L A+G +D ML+
Sbjct: 768 MIASGSQDKTVRFWDLRVPSCVRVVGTTFHGTGSAVASVAVDPSGRLLATGQEDSSCMLY 827
Query: 427 DLNDGKHLHTL-DHNDIITALCFSPN-RYWLCAAFGPSIKIWDLESKEMVEELRPEIINQ 254
D+ G+ + + H+ + ++ FSP Y L ++ IK+ DL+ ++ ++L ++ +
Sbjct: 828 DIRGGRMVQSYHPHSSDVRSVRFSPGAHYLLTGSYDMKIKVTDLQG-DLTKQLPIMVVGE 886
Query: 253 TQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVW 149
K QC W T + + +D T+ +W
Sbjct: 887 ---HKDKVIQC---RWHTQDLSFLSSSADRTVTLW 915
Score = 34.7 bits (76), Expect = 0.34
Identities = 20/100 (20%), Positives = 45/100 (45%), Gaps = 1/100 (1%)
Frame = -2
Query: 718 GSRDKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
GS+DKT++ W+ + C + H + + + + ++ + D + ++ +
Sbjct: 772 GSQDKTVRFWDLRVPSCVRVVGTTFHGTGSAVASVAVDPSGRLLATGQEDSSCMLYDIRG 831
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDL 422
++ ++ HS + +V SP +G DMK + DL
Sbjct: 832 GRMVQSYHPHSSDVRSVRFSPGAHYLLTGSYDMKIKVTDL 871
>BX679664-3|CAH71326.1| 920|Homo sapiens WD repeat domain 47 protein.
Length = 920
Score = 56.4 bits (130), Expect = 1e-07
Identities = 40/155 (25%), Positives = 74/155 (47%), Gaps = 6/155 (3%)
Frame = -2
Query: 595 IIVSCGWDRTVKVWHLT--NCKLKINHLGHS--GYLNTVTVSPDGSLCASGGKDMKAMLW 428
+I S D+TV+ W L +C + H + +V V P G L A+G +D ML+
Sbjct: 769 MIASGSQDKTVRFWDLRVPSCVRVVGTTFHGTGSAVASVAVDPSGRLLATGQEDSSCMLY 828
Query: 427 DLNDGKHLHTL-DHNDIITALCFSPN-RYWLCAAFGPSIKIWDLESKEMVEELRPEIINQ 254
D+ G+ + + H+ + ++ FSP Y L ++ IK+ DL+ ++ ++L ++ +
Sbjct: 829 DIRGGRMVQSYHPHSSDVRSVRFSPGAHYLLTGSYDMKIKVTDLQG-DLTKQLPIMVVGE 887
Query: 253 TQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVW 149
K QC W T + + +D T+ +W
Sbjct: 888 ---HKDKVIQC---RWHTQDLSFLSSSADRTVTLW 916
Score = 34.7 bits (76), Expect = 0.34
Identities = 20/100 (20%), Positives = 45/100 (45%), Gaps = 1/100 (1%)
Frame = -2
Query: 718 GSRDKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
GS+DKT++ W+ + C + H + + + + ++ + D + ++ +
Sbjct: 773 GSQDKTVRFWDLRVPSCVRVVGTTFHGTGSAVASVAVDPSGRLLATGQEDSSCMLYDIRG 832
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDL 422
++ ++ HS + +V SP +G DMK + DL
Sbjct: 833 GRMVQSYHPHSSDVRSVRFSPGAHYLLTGSYDMKIKVTDL 872
>BC039254-1|AAH39254.1| 893|Homo sapiens WDR47 protein protein.
Length = 893
Score = 56.4 bits (130), Expect = 1e-07
Identities = 40/155 (25%), Positives = 74/155 (47%), Gaps = 6/155 (3%)
Frame = -2
Query: 595 IIVSCGWDRTVKVWHLT--NCKLKINHLGHS--GYLNTVTVSPDGSLCASGGKDMKAMLW 428
+I S D+TV+ W L +C + H + +V V P G L A+G +D ML+
Sbjct: 742 MIASGSQDKTVRFWDLRVPSCVRVVGTTFHGTGSAVASVAVDPSGRLLATGQEDSSCMLY 801
Query: 427 DLNDGKHLHTL-DHNDIITALCFSPN-RYWLCAAFGPSIKIWDLESKEMVEELRPEIINQ 254
D+ G+ + + H+ + ++ FSP Y L ++ IK+ DL+ ++ ++L ++ +
Sbjct: 802 DIRGGRMVQSYHPHSSDVRSVRFSPGAHYLLTGSYDMKIKVTDLQG-DLTKQLPIMVVGE 860
Query: 253 TQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVW 149
K QC W T + + +D T+ +W
Sbjct: 861 ---HKDKVIQC---RWHTQDLSFLSSSADRTVTLW 889
Score = 34.7 bits (76), Expect = 0.34
Identities = 20/100 (20%), Positives = 45/100 (45%), Gaps = 1/100 (1%)
Frame = -2
Query: 718 GSRDKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
GS+DKT++ W+ + C + H + + + + ++ + D + ++ +
Sbjct: 746 GSQDKTVRFWDLRVPSCVRVVGTTFHGTGSAVASVAVDPSGRLLATGQEDSSCMLYDIRG 805
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDL 422
++ ++ HS + +V SP +G DMK + DL
Sbjct: 806 GRMVQSYHPHSSDVRSVRFSPGAHYLLTGSYDMKIKVTDL 845
>BC017364-1|AAH17364.1| 743|Homo sapiens transducin-like enhancer of
split 2 (E(sp1) homolog, Drosophila) protein.
Length = 743
Score = 56.4 bits (130), Expect = 1e-07
Identities = 47/196 (23%), Positives = 82/196 (41%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
G T+ +W+ LA I+ + S +C + + + SC D + VW L N
Sbjct: 521 GGEASTLSIWD-LAAPTPRIKAELTSSAPACYALAVSPDAKVCFSCCSDGNIVVWDLQNQ 579
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDIITALCFS 359
+ GH+ + + +S G+ +GG D WDL +G+ L D + I +L
Sbjct: 580 TMVRQFQGHTDGASCIDISDYGTRLWTGGLDNTVRCWDLREGRQLQQHDFSSQIFSLGHC 639
Query: 358 PNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFA 179
PN+ WL S + E++ +PE Q ++ LSL +++ G+ +
Sbjct: 640 PNQDWLAVGMESS-------NVEILHVRKPEKY-QLHLHES---CVLSLKFASCGRWFVS 688
Query: 178 GYSDNTIRVWQVSISA 131
DN + W+ A
Sbjct: 689 TGKDNLLNAWRTPYGA 704
Score = 42.3 bits (95), Expect = 0.002
Identities = 41/159 (25%), Positives = 64/159 (40%), Gaps = 10/159 (6%)
Frame = -2
Query: 589 VSCGWDRTVKVWHLTNCKLK-----INHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWD 425
V G VKVW + K ++ L Y+ + + PDG GG+ +WD
Sbjct: 472 VYTGGKGCVKVWDVGQPGAKTPVAQLDCLNRDNYIRSCKLLPDGRSLIVGGEASTLSIWD 531
Query: 424 L---NDGKHLHTLDHNDIITALCFSPNR--YWLCAAFGPSIKIWDLESKEMVEELRPEII 260
L AL SP+ + C + G +I +WDL+++ MV + +
Sbjct: 532 LAAPTPRIKAELTSSAPACYALAVSPDAKVCFSCCSDG-NIVVWDLQNQTMVRQFQ---- 586
Query: 259 NQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQV 143
TD C+ + S G L+ G DNT+R W +
Sbjct: 587 -----GHTDGASCIDI--SDYGTRLWTGGLDNTVRCWDL 618
Score = 31.1 bits (67), Expect = 4.1
Identities = 22/94 (23%), Positives = 46/94 (48%), Gaps = 3/94 (3%)
Frame = -2
Query: 412 KHLHTLDHNDIITALCFSPNRYWLCAAFGPSIKIWDL---ESKEMVEELRPEIINQTQTS 242
+ LHTL H +++ A+ S + + +K+WD+ +K V +L + +N+
Sbjct: 449 RQLHTLAHGEVVCAVTISGSTQHVYTGGKGCVKVWDVGQPGAKTPVAQL--DCLNRDNYI 506
Query: 241 KTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQVS 140
++ C L DG++L G +T+ +W ++
Sbjct: 507 RS----CKLL---PDGRSLIVGGEASTLSIWDLA 533
>AY358182-1|AAQ88549.1| 470|Homo sapiens SSGL9393 protein.
Length = 470
Score = 56.4 bits (130), Expect = 1e-07
Identities = 35/131 (26%), Positives = 67/131 (51%), Gaps = 4/131 (3%)
Frame = -2
Query: 652 DGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHL--TNCKLKINHLGHSGYLNTVTVSP 479
D H V+ V+FSP + ++ + G DR VK+W + C+ K + G + + ++
Sbjct: 319 DAHDGEVNAVQFSPG--SRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDS 376
Query: 478 DGSLCASGGKDMKAMLWDLNDGKHLHTL-DHN-DIITALCFSPNRYWLCAAFGPSIKIWD 305
GS + D + +W ++D + HTL H+ +++A N + + ++K+WD
Sbjct: 377 AGSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWD 436
Query: 304 LESKEMVEELR 272
L SK + EE++
Sbjct: 437 LRSK-VCEEIQ 446
Score = 46.4 bits (105), Expect = 1e-04
Identities = 25/100 (25%), Positives = 46/100 (46%), Gaps = 1/100 (1%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAE-CKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
G D+ +KLW E C++ G + ++ + F + A +++ D ++W + +
Sbjct: 340 GGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEF--DSAGSYLLAASNDFASRIWTVDD 397
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDL 422
+L+ GHSG + + D + SG D LWDL
Sbjct: 398 YRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDL 437
Score = 38.7 bits (86), Expect = 0.021
Identities = 36/128 (28%), Positives = 59/128 (46%), Gaps = 4/128 (3%)
Frame = -2
Query: 514 HSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGK--HLHTLD-HNDIITALCF-SPNRY 347
H G +N V SP L A+GG D + LW++ K +L N IT++ F S Y
Sbjct: 321 HDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGSY 380
Query: 346 WLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSD 167
L A+ + +IW V++ R + T T + + LS + D + +G D
Sbjct: 381 LLAASNDFASRIW------TVDDYR---LRHTLTGHSG--KVLSAKFLLDNARIVSGSHD 429
Query: 166 NTIRVWQV 143
T+++W +
Sbjct: 430 RTLKLWDL 437
>AL449266-4|CAI14352.1| 891|Homo sapiens WD repeat domain 47 protein.
Length = 891
Score = 56.4 bits (130), Expect = 1e-07
Identities = 40/155 (25%), Positives = 74/155 (47%), Gaps = 6/155 (3%)
Frame = -2
Query: 595 IIVSCGWDRTVKVWHLT--NCKLKINHLGHS--GYLNTVTVSPDGSLCASGGKDMKAMLW 428
+I S D+TV+ W L +C + H + +V V P G L A+G +D ML+
Sbjct: 740 MIASGSQDKTVRFWDLRVPSCVRVVGTTFHGTGSAVASVAVDPSGRLLATGQEDSSCMLY 799
Query: 427 DLNDGKHLHTL-DHNDIITALCFSPN-RYWLCAAFGPSIKIWDLESKEMVEELRPEIINQ 254
D+ G+ + + H+ + ++ FSP Y L ++ IK+ DL+ ++ ++L ++ +
Sbjct: 800 DIRGGRMVQSYHPHSSDVRSVRFSPGAHYLLTGSYDMKIKVTDLQG-DLTKQLPIMVVGE 858
Query: 253 TQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVW 149
K QC W T + + +D T+ +W
Sbjct: 859 ---HKDKVIQC---RWHTQDLSFLSSSADRTVTLW 887
Score = 34.7 bits (76), Expect = 0.34
Identities = 20/100 (20%), Positives = 45/100 (45%), Gaps = 1/100 (1%)
Frame = -2
Query: 718 GSRDKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
GS+DKT++ W+ + C + H + + + + ++ + D + ++ +
Sbjct: 744 GSQDKTVRFWDLRVPSCVRVVGTTFHGTGSAVASVAVDPSGRLLATGQEDSSCMLYDIRG 803
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDL 422
++ ++ HS + +V SP +G DMK + DL
Sbjct: 804 GRMVQSYHPHSSDVRSVRFSPGAHYLLTGSYDMKIKVTDL 843
>AL449266-3|CAI14353.1| 919|Homo sapiens WD repeat domain 47 protein.
Length = 919
Score = 56.4 bits (130), Expect = 1e-07
Identities = 40/155 (25%), Positives = 74/155 (47%), Gaps = 6/155 (3%)
Frame = -2
Query: 595 IIVSCGWDRTVKVWHLT--NCKLKINHLGHS--GYLNTVTVSPDGSLCASGGKDMKAMLW 428
+I S D+TV+ W L +C + H + +V V P G L A+G +D ML+
Sbjct: 768 MIASGSQDKTVRFWDLRVPSCVRVVGTTFHGTGSAVASVAVDPSGRLLATGQEDSSCMLY 827
Query: 427 DLNDGKHLHTL-DHNDIITALCFSPN-RYWLCAAFGPSIKIWDLESKEMVEELRPEIINQ 254
D+ G+ + + H+ + ++ FSP Y L ++ IK+ DL+ ++ ++L ++ +
Sbjct: 828 DIRGGRMVQSYHPHSSDVRSVRFSPGAHYLLTGSYDMKIKVTDLQG-DLTKQLPIMVVGE 886
Query: 253 TQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVW 149
K QC W T + + +D T+ +W
Sbjct: 887 ---HKDKVIQC---RWHTQDLSFLSSSADRTVTLW 915
Score = 34.7 bits (76), Expect = 0.34
Identities = 20/100 (20%), Positives = 45/100 (45%), Gaps = 1/100 (1%)
Frame = -2
Query: 718 GSRDKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
GS+DKT++ W+ + C + H + + + + ++ + D + ++ +
Sbjct: 772 GSQDKTVRFWDLRVPSCVRVVGTTFHGTGSAVASVAVDPSGRLLATGQEDSSCMLYDIRG 831
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDL 422
++ ++ HS + +V SP +G DMK + DL
Sbjct: 832 GRMVQSYHPHSSDVRSVRFSPGAHYLLTGSYDMKIKVTDL 871
>AL449266-2|CAI14351.1| 920|Homo sapiens WD repeat domain 47 protein.
Length = 920
Score = 56.4 bits (130), Expect = 1e-07
Identities = 40/155 (25%), Positives = 74/155 (47%), Gaps = 6/155 (3%)
Frame = -2
Query: 595 IIVSCGWDRTVKVWHLT--NCKLKINHLGHS--GYLNTVTVSPDGSLCASGGKDMKAMLW 428
+I S D+TV+ W L +C + H + +V V P G L A+G +D ML+
Sbjct: 769 MIASGSQDKTVRFWDLRVPSCVRVVGTTFHGTGSAVASVAVDPSGRLLATGQEDSSCMLY 828
Query: 427 DLNDGKHLHTL-DHNDIITALCFSPN-RYWLCAAFGPSIKIWDLESKEMVEELRPEIINQ 254
D+ G+ + + H+ + ++ FSP Y L ++ IK+ DL+ ++ ++L ++ +
Sbjct: 829 DIRGGRMVQSYHPHSSDVRSVRFSPGAHYLLTGSYDMKIKVTDLQG-DLTKQLPIMVVGE 887
Query: 253 TQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVW 149
K QC W T + + +D T+ +W
Sbjct: 888 ---HKDKVIQC---RWHTQDLSFLSSSADRTVTLW 916
Score = 34.7 bits (76), Expect = 0.34
Identities = 20/100 (20%), Positives = 45/100 (45%), Gaps = 1/100 (1%)
Frame = -2
Query: 718 GSRDKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
GS+DKT++ W+ + C + H + + + + ++ + D + ++ +
Sbjct: 773 GSQDKTVRFWDLRVPSCVRVVGTTFHGTGSAVASVAVDPSGRLLATGQEDSSCMLYDIRG 832
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDL 422
++ ++ HS + +V SP +G DMK + DL
Sbjct: 833 GRMVQSYHPHSSDVRSVRFSPGAHYLLTGSYDMKIKVTDL 872
>AC007766-2|AAD38075.1| 553|Homo sapiens TLE2_HUMAN [AA 191- 743]
protein.
Length = 553
Score = 56.4 bits (130), Expect = 1e-07
Identities = 47/196 (23%), Positives = 82/196 (41%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
G T+ +W+ LA I+ + S +C + + + SC D + VW L N
Sbjct: 331 GGEASTLSIWD-LAAPTPRIKAELTSSAPACYALAVSPDAKVCFSCCSDGNIVVWDLQNQ 389
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDIITALCFS 359
+ GH+ + + +S G+ +GG D WDL +G+ L D + I +L
Sbjct: 390 TMVRQFQGHTDGASCIDISDYGTRLWTGGLDNTVRCWDLREGRQLQQHDFSSQIFSLGHC 449
Query: 358 PNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFA 179
PN+ WL S + E++ +PE Q ++ LSL +++ G+ +
Sbjct: 450 PNQDWLAVGMESS-------NVEILHVRKPEKY-QLHLHES---CVLSLKFASCGRWFVS 498
Query: 178 GYSDNTIRVWQVSISA 131
DN + W+ A
Sbjct: 499 TGKDNLLNAWRTPYGA 514
Score = 42.3 bits (95), Expect = 0.002
Identities = 41/159 (25%), Positives = 64/159 (40%), Gaps = 10/159 (6%)
Frame = -2
Query: 589 VSCGWDRTVKVWHLTNCKLK-----INHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWD 425
V G VKVW + K ++ L Y+ + + PDG GG+ +WD
Sbjct: 282 VYTGGKGCVKVWDVGQPGAKTPVAQLDCLNRDNYIRSCKLLPDGRSLIVGGEASTLSIWD 341
Query: 424 L---NDGKHLHTLDHNDIITALCFSPNR--YWLCAAFGPSIKIWDLESKEMVEELRPEII 260
L AL SP+ + C + G +I +WDL+++ MV + +
Sbjct: 342 LAAPTPRIKAELTSSAPACYALAVSPDAKVCFSCCSDG-NIVVWDLQNQTMVRQFQ---- 396
Query: 259 NQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQV 143
TD C+ + S G L+ G DNT+R W +
Sbjct: 397 -----GHTDGASCIDI--SDYGTRLWTGGLDNTVRCWDL 428
Score = 31.1 bits (67), Expect = 4.1
Identities = 22/94 (23%), Positives = 46/94 (48%), Gaps = 3/94 (3%)
Frame = -2
Query: 412 KHLHTLDHNDIITALCFSPNRYWLCAAFGPSIKIWDL---ESKEMVEELRPEIINQTQTS 242
+ LHTL H +++ A+ S + + +K+WD+ +K V +L + +N+
Sbjct: 259 RQLHTLAHGEVVCAVTISGSTQHVYTGGKGCVKVWDVGQPGAKTPVAQL--DCLNRDNYI 316
Query: 241 KTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQVS 140
++ C L DG++L G +T+ +W ++
Sbjct: 317 RS----CKLL---PDGRSLIVGGEASTLSIWDLA 343
>AB020700-1|BAA74916.2| 974|Homo sapiens KIAA0893 protein protein.
Length = 974
Score = 56.4 bits (130), Expect = 1e-07
Identities = 40/155 (25%), Positives = 74/155 (47%), Gaps = 6/155 (3%)
Frame = -2
Query: 595 IIVSCGWDRTVKVWHLT--NCKLKINHLGHS--GYLNTVTVSPDGSLCASGGKDMKAMLW 428
+I S D+TV+ W L +C + H + +V V P G L A+G +D ML+
Sbjct: 823 MIASGSQDKTVRFWDLRVPSCVRVVGTTFHGTGSAVASVAVDPSGRLLATGQEDSSCMLY 882
Query: 427 DLNDGKHLHTL-DHNDIITALCFSPN-RYWLCAAFGPSIKIWDLESKEMVEELRPEIINQ 254
D+ G+ + + H+ + ++ FSP Y L ++ IK+ DL+ ++ ++L ++ +
Sbjct: 883 DIRGGRMVQSYHPHSSDVRSVRFSPGAHYLLTGSYDMKIKVTDLQG-DLTKQLPIMVVGE 941
Query: 253 TQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVW 149
K QC W T + + +D T+ +W
Sbjct: 942 ---HKDKVIQC---RWHTQDLSFLSSSADRTVTLW 970
Score = 34.7 bits (76), Expect = 0.34
Identities = 20/100 (20%), Positives = 45/100 (45%), Gaps = 1/100 (1%)
Frame = -2
Query: 718 GSRDKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
GS+DKT++ W+ + C + H + + + + ++ + D + ++ +
Sbjct: 827 GSQDKTVRFWDLRVPSCVRVVGTTFHGTGSAVASVAVDPSGRLLATGQEDSSCMLYDIRG 886
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDL 422
++ ++ HS + +V SP +G DMK + DL
Sbjct: 887 GRMVQSYHPHSSDVRSVRFSPGAHYLLTGSYDMKIKVTDL 926
>BC150255-1|AAI50256.1| 1237|Homo sapiens apoptotic peptidase
activating factor 1 protein.
Length = 1237
Score = 56.0 bits (129), Expect = 1e-07
Identities = 31/98 (31%), Positives = 50/98 (51%), Gaps = 1/98 (1%)
Frame = -2
Query: 715 SRDKTIKLWNTLA-ECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
S DK +K+WN++ E +T D HS+ V+C F+ + + ++ + D +K+W L
Sbjct: 665 SVDKKVKIWNSMTGELVHTY--DEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLNQK 722
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWD 425
+ + GH+ +N SPD L AS D LWD
Sbjct: 723 ECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWD 760
Score = 52.4 bits (120), Expect = 2e-06
Identities = 49/194 (25%), Positives = 84/194 (43%), Gaps = 3/194 (1%)
Frame = -2
Query: 715 SRDKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
S D I++WN L +C + GH + V R N ++S +D TVKVW++
Sbjct: 1011 SDDAEIQVWNWQLDKCIFL---RGHQETVKDFRLLKNSR---LLSWSFDGTVKVWNIITG 1064
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCF 362
+ + + H G + + +S D + +S D A +W + LH L HN + F
Sbjct: 1065 NKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELRGHNGCVRCSAF 1124
Query: 361 SPNRYWLCAA-FGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTL 185
S + L I+IW++ + E++ P + + T L +S DG+ L
Sbjct: 1125 SVDSTLLATGDDNGEIRIWNVSNGELLHLCAP---LSEEGAATHGGWVTDLCFSPDGKML 1181
Query: 184 FAGYSDNTIRVWQV 143
+ + I+ W V
Sbjct: 1182 IS--AGGYIKWWNV 1193
Score = 51.6 bits (118), Expect = 3e-06
Identities = 41/155 (26%), Positives = 66/155 (42%), Gaps = 4/155 (2%)
Frame = -2
Query: 646 HSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSL 467
H+D V FS + I SCG D+T++V+ + + H + S D
Sbjct: 603 HTDAVYHACFSEDGQR--IASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRF 660
Query: 466 CASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALCFSPNRYWLCAAFGPS---IKIWDLE 299
A+ D K +W+ G+ +HT D H++ + F+ + + L A G S +K+WDL
Sbjct: 661 IATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLN 720
Query: 298 SKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDG 194
KE + N + P L + S DG
Sbjct: 721 QKECRNTMFGH-TNSVNHCRFSPDDKLLASCSADG 754
Score = 50.8 bits (116), Expect = 5e-06
Identities = 52/208 (25%), Positives = 89/208 (42%), Gaps = 17/208 (8%)
Frame = -2
Query: 718 GSRDKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
GS D +KLW+ EC+ T+ GH++ V+ RFSP+ + ++ SC D T+K+W T+
Sbjct: 708 GSSDCFLKLWDLNQKECRNTMF--GHTNSVNHCRFSPD--DKLLASCSADGTLKLWDATS 763
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSL---CASGGKD---------MKAMLWDLNDG---KH 407
+ + +LN D + C S D K L+D++
Sbjct: 764 ANERKSINVKQFFLNLEDPQEDMEVIVKCCSWSADGARIMVAAKNKIFLFDIHTSGLLGE 823
Query: 406 LHTLDHNDIITALCFSPNRYWLCAAFGP-SIKIWDLESKEMVEELRPEIINQTQTSKTDP 230
+HT H+ I FSP + A +++W+ +S+ V + R +
Sbjct: 824 IHT-GHHSTIQYCDFSPQNHLAVVALSQYCVELWNTDSRSKVADCRGHL----------- 871
Query: 229 PQCLSLAWSTDGQTLFAGYSDNTIRVWQ 146
+ +S DG + D TIR+W+
Sbjct: 872 SWVHGVMFSPDGSSFLTSSDDQTIRLWE 899
>BC036713-1|AAH36713.1| 542|Homo sapiens ATG16L2 protein protein.
Length = 542
Score = 56.0 bits (129), Expect = 1e-07
Identities = 34/121 (28%), Positives = 58/121 (47%), Gaps = 4/121 (3%)
Frame = -2
Query: 652 DGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHL--GHSGYLNTVTVSP 479
D H V+ VRF PN + ++ + G DR + +W++ +L+ N G G + +V P
Sbjct: 256 DAHLSEVNAVRFGPNSS--LLATGGADRLIHLWNVVGSRLEANQTLEGAGGSITSVDFDP 313
Query: 478 DGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALCFSPNRYW-LCAAFGPSIKIWD 305
G + + A LW + + + TL H D +TA F R+ + + ++K WD
Sbjct: 314 SGYQVLAATYNQAAQLWKVGEAQSKETLSGHKDKVTAAKFKLTRHQAVTGSRDRTVKEWD 373
Query: 304 L 302
L
Sbjct: 374 L 374
Score = 35.9 bits (79), Expect = 0.15
Identities = 26/85 (30%), Positives = 41/85 (48%), Gaps = 5/85 (5%)
Frame = -2
Query: 514 HSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHL---HTLD-HNDIITALCFSPNRY 347
H +N V P+ SL A+GG D LW++ G L TL+ IT++ F P+ Y
Sbjct: 258 HLSEVNAVRFGPNSSLLATGGADRLIHLWNV-VGSRLEANQTLEGAGGSITSVDFDPSGY 316
Query: 346 W-LCAAFGPSIKIWDLESKEMVEEL 275
L A + + ++W + + E L
Sbjct: 317 QVLAATYNQAAQLWKVGEAQSKETL 341
Score = 31.5 bits (68), Expect = 3.1
Identities = 31/108 (28%), Positives = 45/108 (41%), Gaps = 5/108 (4%)
Frame = -2
Query: 718 GSRDKTIKLWNTLA-ECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHL-- 548
G D+ I+ W++ C I G S +H ++SC D T+KV L
Sbjct: 402 GHNDQKIRFWDSRGPHCTQVIPVQGR-----VTSLSLSHDQLHLLSCSRDNTLKVIDLRV 456
Query: 547 TNCKLKINHLGHS-GYLNTVTV-SPDGSLCASGGKDMKAMLWDLNDGK 410
+N + G G T V SPD S +G D +WD++ GK
Sbjct: 457 SNIRQVFRADGFKCGSDWTKAVFSPDRSYALAGSCDGALYIWDVDTGK 504
>AK093017-1|BAC04021.1| 619|Homo sapiens protein ( Homo sapiens
cDNA FLJ35698 fis, clone SPLEN2019839, weakly similar to
TIPD PROTEIN. ).
Length = 619
Score = 56.0 bits (129), Expect = 1e-07
Identities = 34/121 (28%), Positives = 58/121 (47%), Gaps = 4/121 (3%)
Frame = -2
Query: 652 DGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHL--GHSGYLNTVTVSP 479
D H V+ VRF PN + ++ + G DR + +W++ +L+ N G G + +V P
Sbjct: 333 DAHLSEVNAVRFGPNSS--LLATGGADRLIHLWNVVGSRLEANQTLEGAGGSITSVDFDP 390
Query: 478 DGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALCFSPNRYW-LCAAFGPSIKIWD 305
G + + A LW + + + TL H D +TA F R+ + + ++K WD
Sbjct: 391 SGYQVLAATYNQAAQLWKVGEAQSKETLSGHKDKVTAAKFKLTRHQAVTGSRDRTVKEWD 450
Query: 304 L 302
L
Sbjct: 451 L 451
Score = 35.9 bits (79), Expect = 0.15
Identities = 26/85 (30%), Positives = 41/85 (48%), Gaps = 5/85 (5%)
Frame = -2
Query: 514 HSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHL---HTLD-HNDIITALCFSPNRY 347
H +N V P+ SL A+GG D LW++ G L TL+ IT++ F P+ Y
Sbjct: 335 HLSEVNAVRFGPNSSLLATGGADRLIHLWNV-VGSRLEANQTLEGAGGSITSVDFDPSGY 393
Query: 346 W-LCAAFGPSIKIWDLESKEMVEEL 275
L A + + ++W + + E L
Sbjct: 394 QVLAATYNQAAQLWKVGEAQSKETL 418
Score = 31.1 bits (67), Expect = 4.1
Identities = 31/108 (28%), Positives = 45/108 (41%), Gaps = 5/108 (4%)
Frame = -2
Query: 718 GSRDKTIKLWNTLA-ECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHL-- 548
G D+ I+ W++ C I G S +H ++SC D T+KV L
Sbjct: 479 GHNDQKIRFWDSREPHCTQVIPVQGR-----VTSLSLSHDQLHLLSCSRDNTLKVIDLRV 533
Query: 547 TNCKLKINHLGHS-GYLNTVTV-SPDGSLCASGGKDMKAMLWDLNDGK 410
+N + G G T V SPD S +G D +WD++ GK
Sbjct: 534 SNIRQVFRADGFKCGSDWTKAVFSPDRSYALAGSCDGALYIWDVDTGK 581
>AJ243048-1|CAB55588.1| 1248|Homo sapiens apoptotic protease
activating factor 1 protein.
Length = 1248
Score = 56.0 bits (129), Expect = 1e-07
Identities = 31/98 (31%), Positives = 50/98 (51%), Gaps = 1/98 (1%)
Frame = -2
Query: 715 SRDKTIKLWNTLA-ECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
S DK +K+WN++ E +T D HS+ V+C F+ + + ++ + D +K+W L
Sbjct: 676 SVDKKVKIWNSMTGELVHTY--DEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLNQK 733
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWD 425
+ + GH+ +N SPD L AS D LWD
Sbjct: 734 ECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWD 771
Score = 52.4 bits (120), Expect = 2e-06
Identities = 49/194 (25%), Positives = 84/194 (43%), Gaps = 3/194 (1%)
Frame = -2
Query: 715 SRDKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
S D I++WN L +C + GH + V R N ++S +D TVKVW++
Sbjct: 1022 SDDAEIQVWNWQLDKCIFL---RGHQETVKDFRLLKNSR---LLSWSFDGTVKVWNIITG 1075
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCF 362
+ + + H G + + +S D + +S D A +W + LH L HN + F
Sbjct: 1076 NKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELRGHNGCVRCSAF 1135
Query: 361 SPNRYWLCAA-FGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTL 185
S + L I+IW++ + E++ P + + T L +S DG+ L
Sbjct: 1136 SVDSTLLATGDDNGEIRIWNVSNGELLHLCAP---LSEEGAATHGGWVTDLCFSPDGKML 1192
Query: 184 FAGYSDNTIRVWQV 143
+ + I+ W V
Sbjct: 1193 IS--AGGYIKWWNV 1204
Score = 51.6 bits (118), Expect = 3e-06
Identities = 41/155 (26%), Positives = 66/155 (42%), Gaps = 4/155 (2%)
Frame = -2
Query: 646 HSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSL 467
H+D V FS + I SCG D+T++V+ + + H + S D
Sbjct: 614 HTDAVYHACFSEDGQR--IASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRF 671
Query: 466 CASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALCFSPNRYWLCAAFGPS---IKIWDLE 299
A+ D K +W+ G+ +HT D H++ + F+ + + L A G S +K+WDL
Sbjct: 672 IATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLN 731
Query: 298 SKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDG 194
KE + N + P L + S DG
Sbjct: 732 QKECRNTMFGH-TNSVNHCRFSPDDKLLASCSADG 765
Score = 50.8 bits (116), Expect = 5e-06
Identities = 52/208 (25%), Positives = 89/208 (42%), Gaps = 17/208 (8%)
Frame = -2
Query: 718 GSRDKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
GS D +KLW+ EC+ T+ GH++ V+ RFSP+ + ++ SC D T+K+W T+
Sbjct: 719 GSSDCFLKLWDLNQKECRNTMF--GHTNSVNHCRFSPD--DKLLASCSADGTLKLWDATS 774
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSL---CASGGKD---------MKAMLWDLNDG---KH 407
+ + +LN D + C S D K L+D++
Sbjct: 775 ANERKSINVKQFFLNLEDPQEDMEVIVKCCSWSADGARIMVAAKNKIFLFDIHTSGLLGE 834
Query: 406 LHTLDHNDIITALCFSPNRYWLCAAFGP-SIKIWDLESKEMVEELRPEIINQTQTSKTDP 230
+HT H+ I FSP + A +++W+ +S+ V + R +
Sbjct: 835 IHT-GHHSTIQYCDFSPQNHLAVVALSQYCVELWNTDSRSKVADCRGHL----------- 882
Query: 229 PQCLSLAWSTDGQTLFAGYSDNTIRVWQ 146
+ +S DG + D TIR+W+
Sbjct: 883 SWVHGVMFSPDGSSFLTSSDDQTIRLWE 910
>AJ243009-1|CAB55585.1| 1248|Homo sapiens apoptotic protease
activating factor 1 protein.
Length = 1248
Score = 56.0 bits (129), Expect = 1e-07
Identities = 31/98 (31%), Positives = 50/98 (51%), Gaps = 1/98 (1%)
Frame = -2
Query: 715 SRDKTIKLWNTLA-ECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
S DK +K+WN++ E +T D HS+ V+C F+ + + ++ + D +K+W L
Sbjct: 676 SVDKKVKIWNSMTGELVHTY--DEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLNQK 733
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWD 425
+ + GH+ +N SPD L AS D LWD
Sbjct: 734 ECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWD 771
Score = 52.4 bits (120), Expect = 2e-06
Identities = 49/194 (25%), Positives = 84/194 (43%), Gaps = 3/194 (1%)
Frame = -2
Query: 715 SRDKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
S D I++WN L +C + GH + V R N ++S +D TVKVW++
Sbjct: 1022 SDDAEIQVWNWQLDKCIFL---RGHQETVKDFRLLKNSR---LLSWSFDGTVKVWNIITG 1075
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCF 362
+ + + H G + + +S D + +S D A +W + LH L HN + F
Sbjct: 1076 NKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELRGHNGCVRCSAF 1135
Query: 361 SPNRYWLCAA-FGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTL 185
S + L I+IW++ + E++ P + + T L +S DG+ L
Sbjct: 1136 SVDSTLLATGDDNGEIRIWNVSNGELLHLCAP---LSEEGAATHGGWVTDLCFSPDGKML 1192
Query: 184 FAGYSDNTIRVWQV 143
+ + I+ W V
Sbjct: 1193 IS--AGGYIKWWNV 1204
Score = 51.6 bits (118), Expect = 3e-06
Identities = 41/155 (26%), Positives = 66/155 (42%), Gaps = 4/155 (2%)
Frame = -2
Query: 646 HSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSL 467
H+D V FS + I SCG D+T++V+ + + H + S D
Sbjct: 614 HTDAVYHACFSEDGQR--IASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRF 671
Query: 466 CASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALCFSPNRYWLCAAFGPS---IKIWDLE 299
A+ D K +W+ G+ +HT D H++ + F+ + + L A G S +K+WDL
Sbjct: 672 IATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLN 731
Query: 298 SKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDG 194
KE + N + P L + S DG
Sbjct: 732 QKECRNTMFGH-TNSVNHCRFSPDDKLLASCSADG 765
Score = 47.6 bits (108), Expect = 4e-05
Identities = 51/208 (24%), Positives = 88/208 (42%), Gaps = 17/208 (8%)
Frame = -2
Query: 718 GSRDKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
GS D +KLW+ EC+ T+ GH++ V+ RFSP+ + ++ SC D T+K+W T+
Sbjct: 719 GSSDCFLKLWDLNQKECRNTMF--GHTNSVNHCRFSPD--DKLLASCSADGTLKLWDATS 774
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSL---CASGGKD---------MKAMLWDLNDG---KH 407
+ + +LN D + C S D K L+ ++
Sbjct: 775 ANERKSINVKQFFLNLEDPQEDMEVIVKCCSWSADGARIMVAAKNKIFLFAIHTSGLLGE 834
Query: 406 LHTLDHNDIITALCFSPNRYWLCAAFGP-SIKIWDLESKEMVEELRPEIINQTQTSKTDP 230
+HT H+ I FSP + A +++W+ +S+ V + R +
Sbjct: 835 IHT-GHHSTIQYCDFSPQNHLAVVALSQYCVELWNTDSRSKVADCRGHL----------- 882
Query: 229 PQCLSLAWSTDGQTLFAGYSDNTIRVWQ 146
+ +S DG + D TIR+W+
Sbjct: 883 SWVHGVMFSPDGSSFLTSSDDQTIRLWE 910
>AF149794-1|AAD34016.1| 1248|Homo sapiens apoptotic protease
activating factor 1 protein.
Length = 1248
Score = 56.0 bits (129), Expect = 1e-07
Identities = 31/98 (31%), Positives = 50/98 (51%), Gaps = 1/98 (1%)
Frame = -2
Query: 715 SRDKTIKLWNTLA-ECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
S DK +K+WN++ E +T D HS+ V+C F+ + + ++ + D +K+W L
Sbjct: 676 SVDKKVKIWNSMTGELVHTY--DEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLNQK 733
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWD 425
+ + GH+ +N SPD L AS D LWD
Sbjct: 734 ECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWD 771
Score = 52.4 bits (120), Expect = 2e-06
Identities = 49/194 (25%), Positives = 84/194 (43%), Gaps = 3/194 (1%)
Frame = -2
Query: 715 SRDKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
S D I++WN L +C + GH + V R N ++S +D TVKVW++
Sbjct: 1022 SDDAEIQVWNWQLDKCIFL---RGHQETVKDFRLLKNSR---LLSWSFDGTVKVWNIITG 1075
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCF 362
+ + + H G + + +S D + +S D A +W + LH L HN + F
Sbjct: 1076 NKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELRGHNGCVRCSAF 1135
Query: 361 SPNRYWLCAA-FGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTL 185
S + L I+IW++ + E++ P + + T L +S DG+ L
Sbjct: 1136 SVDSTLLATGDDNGEIRIWNVSNGELLHLCAP---LSEEGAATHGGWVTDLCFSPDGKML 1192
Query: 184 FAGYSDNTIRVWQV 143
+ + I+ W V
Sbjct: 1193 IS--AGGYIKWWNV 1204
Score = 51.6 bits (118), Expect = 3e-06
Identities = 41/155 (26%), Positives = 66/155 (42%), Gaps = 4/155 (2%)
Frame = -2
Query: 646 HSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSL 467
H+D V FS + I SCG D+T++V+ + + H + S D
Sbjct: 614 HTDAVYHACFSEDGQR--IASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRF 671
Query: 466 CASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALCFSPNRYWLCAAFGPS---IKIWDLE 299
A+ D K +W+ G+ +HT D H++ + F+ + + L A G S +K+WDL
Sbjct: 672 IATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLN 731
Query: 298 SKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDG 194
KE + N + P L + S DG
Sbjct: 732 QKECRNTMFGH-TNSVNHCRFSPDDKLLASCSADG 765
Score = 50.8 bits (116), Expect = 5e-06
Identities = 52/208 (25%), Positives = 89/208 (42%), Gaps = 17/208 (8%)
Frame = -2
Query: 718 GSRDKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
GS D +KLW+ EC+ T+ GH++ V+ RFSP+ + ++ SC D T+K+W T+
Sbjct: 719 GSSDCFLKLWDLNQKECRNTMF--GHTNSVNHCRFSPD--DKLLASCSADGTLKLWDATS 774
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSL---CASGGKD---------MKAMLWDLNDG---KH 407
+ + +LN D + C S D K L+D++
Sbjct: 775 ANERKSINVKQFFLNLEDPQEDMEVIVKCCSWSADGARIMVAAKNKIFLFDIHTSGLLGE 834
Query: 406 LHTLDHNDIITALCFSPNRYWLCAAFGP-SIKIWDLESKEMVEELRPEIINQTQTSKTDP 230
+HT H+ I FSP + A +++W+ +S+ V + R +
Sbjct: 835 IHT-GHHSTIQYCDFSPQNHLAVVALSQYCVELWNTDSRSKVADCRGHL----------- 882
Query: 229 PQCLSLAWSTDGQTLFAGYSDNTIRVWQ 146
+ +S DG + D TIR+W+
Sbjct: 883 SWVHGVMFSPDGSSFLTSSDDQTIRLWE 910
>AF134397-1|AAD38344.1| 1237|Homo sapiens apoptotic protease
activating factor-1 long isoform APAF-1L protein.
Length = 1237
Score = 56.0 bits (129), Expect = 1e-07
Identities = 31/98 (31%), Positives = 50/98 (51%), Gaps = 1/98 (1%)
Frame = -2
Query: 715 SRDKTIKLWNTLA-ECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
S DK +K+WN++ E +T D HS+ V+C F+ + + ++ + D +K+W L
Sbjct: 665 SVDKKVKIWNSMTGELVHTY--DEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLNQK 722
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWD 425
+ + GH+ +N SPD L AS D LWD
Sbjct: 723 ECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWD 760
Score = 52.4 bits (120), Expect = 2e-06
Identities = 49/194 (25%), Positives = 84/194 (43%), Gaps = 3/194 (1%)
Frame = -2
Query: 715 SRDKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
S D I++WN L +C + GH + V R N ++S +D TVKVW++
Sbjct: 1011 SDDAEIQVWNWQLDKCIFL---RGHQETVKDFRLLKNSR---LLSWSFDGTVKVWNIITG 1064
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCF 362
+ + + H G + + +S D + +S D A +W + LH L HN + F
Sbjct: 1065 NKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELRGHNGCVRCSAF 1124
Query: 361 SPNRYWLCAA-FGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTL 185
S + L I+IW++ + E++ P + + T L +S DG+ L
Sbjct: 1125 SVDSTLLATGDDNGEIRIWNVSNGELLHLCAP---LSEEGAATHGGWVTDLCFSPDGKML 1181
Query: 184 FAGYSDNTIRVWQV 143
+ + I+ W V
Sbjct: 1182 IS--AGGYIKWWNV 1193
Score = 51.6 bits (118), Expect = 3e-06
Identities = 41/155 (26%), Positives = 66/155 (42%), Gaps = 4/155 (2%)
Frame = -2
Query: 646 HSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSL 467
H+D V FS + I SCG D+T++V+ + + H + S D
Sbjct: 603 HTDAVYHACFSEDGQR--IASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRF 660
Query: 466 CASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALCFSPNRYWLCAAFGPS---IKIWDLE 299
A+ D K +W+ G+ +HT D H++ + F+ + + L A G S +K+WDL
Sbjct: 661 IATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLN 720
Query: 298 SKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDG 194
KE + N + P L + S DG
Sbjct: 721 QKECRNTMFGH-TNSVNHCRFSPDDKLLASCSADG 754
Score = 50.8 bits (116), Expect = 5e-06
Identities = 52/208 (25%), Positives = 89/208 (42%), Gaps = 17/208 (8%)
Frame = -2
Query: 718 GSRDKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
GS D +KLW+ EC+ T+ GH++ V+ RFSP+ + ++ SC D T+K+W T+
Sbjct: 708 GSSDCFLKLWDLNQKECRNTMF--GHTNSVNHCRFSPD--DKLLASCSADGTLKLWDATS 763
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSL---CASGGKD---------MKAMLWDLNDG---KH 407
+ + +LN D + C S D K L+D++
Sbjct: 764 ANERKSINVKQFFLNLEDPQEDMEVIVKCCSWSADGARIMVAAKNKIFLFDIHTSGLLGE 823
Query: 406 LHTLDHNDIITALCFSPNRYWLCAAFGP-SIKIWDLESKEMVEELRPEIINQTQTSKTDP 230
+HT H+ I FSP + A +++W+ +S+ V + R +
Sbjct: 824 IHT-GHHSTIQYCDFSPQNHLAVVALSQYCVELWNTDSRSKVADCRGHL----------- 871
Query: 229 PQCLSLAWSTDGQTLFAGYSDNTIRVWQ 146
+ +S DG + D TIR+W+
Sbjct: 872 SWVHGVMFSPDGSSFLTSSDDQTIRLWE 899
>AB007873-1|BAA24843.2| 1237|Homo sapiens KIAA0413 protein.
Length = 1237
Score = 56.0 bits (129), Expect = 1e-07
Identities = 31/98 (31%), Positives = 50/98 (51%), Gaps = 1/98 (1%)
Frame = -2
Query: 715 SRDKTIKLWNTLA-ECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
S DK +K+WN++ E +T D HS+ V+C F+ + + ++ + D +K+W L
Sbjct: 665 SVDKKVKIWNSMTGELVHTY--DEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLNQK 722
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWD 425
+ + GH+ +N SPD L AS D LWD
Sbjct: 723 ECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWD 760
Score = 52.4 bits (120), Expect = 2e-06
Identities = 49/194 (25%), Positives = 84/194 (43%), Gaps = 3/194 (1%)
Frame = -2
Query: 715 SRDKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
S D I++WN L +C + GH + V R N ++S +D TVKVW++
Sbjct: 1011 SDDAEIQVWNWQLDKCIFL---RGHQETVKDFRLLKNSR---LLSWSFDGTVKVWNIITG 1064
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL-DHNDIITALCF 362
+ + + H G + + +S D + +S D A +W + LH L HN + F
Sbjct: 1065 NKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLLLPLHELRGHNGCVRCSAF 1124
Query: 361 SPNRYWLCAA-FGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTL 185
S + L I+IW++ + E++ P + + T L +S DG+ L
Sbjct: 1125 SVDSTLLATGDDNGEIRIWNVSNGELLHLCAP---LSEEGAATHGGWVTDLCFSPDGKML 1181
Query: 184 FAGYSDNTIRVWQV 143
+ + I+ W V
Sbjct: 1182 IS--AGGYIKWWNV 1193
Score = 51.6 bits (118), Expect = 3e-06
Identities = 41/155 (26%), Positives = 66/155 (42%), Gaps = 4/155 (2%)
Frame = -2
Query: 646 HSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSL 467
H+D V FS + I SCG D+T++V+ + + H + S D
Sbjct: 603 HTDAVYHACFSEDGQR--IASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRF 660
Query: 466 CASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALCFSPNRYWLCAAFGPS---IKIWDLE 299
A+ D K +W+ G+ +HT D H++ + F+ + + L A G S +K+WDL
Sbjct: 661 IATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLN 720
Query: 298 SKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDG 194
KE + N + P L + S DG
Sbjct: 721 QKECRNTMFGH-TNSVNHCRFSPDDKLLASCSADG 754
Score = 50.8 bits (116), Expect = 5e-06
Identities = 52/208 (25%), Positives = 89/208 (42%), Gaps = 17/208 (8%)
Frame = -2
Query: 718 GSRDKTIKLWN-TLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
GS D +KLW+ EC+ T+ GH++ V+ RFSP+ + ++ SC D T+K+W T+
Sbjct: 708 GSSDCFLKLWDLNQKECRNTMF--GHTNSVNHCRFSPD--DKLLASCSADGTLKLWDATS 763
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSL---CASGGKD---------MKAMLWDLNDG---KH 407
+ + +LN D + C S D K L+D++
Sbjct: 764 ANERKSINVKQFFLNLEDPQEDMEVIVKCCSWSADGARIMVAAKNKIFLFDIHTSGLLGE 823
Query: 406 LHTLDHNDIITALCFSPNRYWLCAAFGP-SIKIWDLESKEMVEELRPEIINQTQTSKTDP 230
+HT H+ I FSP + A +++W+ +S+ V + R +
Sbjct: 824 IHT-GHHSTIQYCDFSPQNHLAVVALSQYCVELWNTDSRSKVADCRGHL----------- 871
Query: 229 PQCLSLAWSTDGQTLFAGYSDNTIRVWQ 146
+ +S DG + D TIR+W+
Sbjct: 872 SWVHGVMFSPDGSSFLTSSDDQTIRLWE 899
>BC034964-1|AAH34964.1| 920|Homo sapiens WD repeat domain 47 protein.
Length = 920
Score = 55.2 bits (127), Expect = 2e-07
Identities = 40/155 (25%), Positives = 73/155 (47%), Gaps = 6/155 (3%)
Frame = -2
Query: 595 IIVSCGWDRTVKVWHLT--NCKLKINHLGHS--GYLNTVTVSPDGSLCASGGKDMKAMLW 428
+I S D+TV W L +C + H + +V V P G L A+G +D ML+
Sbjct: 769 MIASGSQDKTVGFWDLRVPSCARVVGTTFHGTGSAVASVAVDPSGRLLATGQEDSSCMLY 828
Query: 427 DLNDGKHLHTL-DHNDIITALCFSPN-RYWLCAAFGPSIKIWDLESKEMVEELRPEIINQ 254
D+ G+ + + H+ + ++ FSP Y L ++ IK+ DL+ ++ ++L ++ +
Sbjct: 829 DIRGGRMVQSYHPHSSDVRSVRFSPGAHYLLTGSYDMKIKVTDLQG-DLTKQLPIMVVGE 887
Query: 253 TQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVW 149
K QC W T + + +D T+ +W
Sbjct: 888 ---HKDKVIQC---RWHTQDLSFLSSSADRTVTLW 916
>AK074434-1|BAB85082.1| 293|Homo sapiens protein ( Homo sapiens
cDNA FLJ23854 fis, clone LNG06315. ).
Length = 293
Score = 55.2 bits (127), Expect = 2e-07
Identities = 42/177 (23%), Positives = 78/177 (44%), Gaps = 6/177 (3%)
Frame = -2
Query: 709 DKTIKLWNTLAE-CKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKL 533
D+ +KLW E C++ G + ++ + F + A +++ D ++W + + +L
Sbjct: 2 DRRVKLWEVFGEKCEFKGSLSGSNAGITSIEF--DSAGSYLLAASNDFASRIWTVDDYRL 59
Query: 532 KINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTL----DHNDII-TAL 368
+ GHSG + + D + SG D LWDL + T+ NDI+ T
Sbjct: 60 RHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCIKTVFAGSSCNDIVCTEQ 119
Query: 367 CFSPNRYWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTD 197
C + F I+ WD+ S+ +V E+ E++ + +P + L+ S D
Sbjct: 120 CV------MSGHFDKKIRFWDIRSESIVREM--ELLGKITALDLNPERTELLSCSRD 168
Score = 31.9 bits (69), Expect = 2.4
Identities = 33/147 (22%), Positives = 60/147 (40%), Gaps = 5/147 (3%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
G DK I+ W+ +E +++ ++ + +P ++SC D +KV L
Sbjct: 124 GHFDKKIRFWDIRSES--IVREMELLGKITALDLNPERTE--LLSCSRDDLLKVIDLRTN 179
Query: 538 KLKINHLGHSGYL-----NTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDIIT 374
+K G+ V SPDGS A+G + +W + GK L ++ T
Sbjct: 180 AIK-QTFSAPGFKCGSDWTRVVFSPDGSYVAAGSAEGSLYIWSVLTGKVEKVLSNS---T 235
Query: 373 ALCFSPNRYWLCAAFGPSIKIWDLESK 293
A P+ W ++ +W ++K
Sbjct: 236 A---HPSMRWRGRPLARTLSVWTKDAK 259
Score = 29.9 bits (64), Expect = 9.6
Identities = 34/201 (16%), Positives = 80/201 (39%), Gaps = 7/201 (3%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAE-CKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
GS D+T+KLW+ ++ C T+ + + C ++S +D+ ++ W + +
Sbjct: 85 GSHDRTLKLWDLRSKVCIKTVFAGSSCNDIVC-------TEQCVMSGHFDKKIRFWDIRS 137
Query: 541 CKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDH-----NDII 377
+ + + G + + ++P+ + S +D + DL T
Sbjct: 138 ESI-VREMELLGKITALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFSAPGFKCGSDW 196
Query: 376 TALCFSPNRYWLCAAFGP-SIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWST 200
T + FSP+ ++ A S+ IW + + ++ + L + + + P W+
Sbjct: 197 TRVVFSPDGSYVAAGSAEGSLYIWSVLTGKVEKVLSNSTAHPSMRWRGRPLARTLSVWTK 256
Query: 199 DGQTLFAGYSDNTIRVWQVSI 137
D + +D +R + +
Sbjct: 257 DAKLCCGHSTDGALRAGRTPV 277
>BC012352-1|AAH12352.1| 366|Homo sapiens WDR31 protein protein.
Length = 366
Score = 54.8 bits (126), Expect = 3e-07
Identities = 43/180 (23%), Positives = 76/180 (42%), Gaps = 4/180 (2%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
G +DKT+ +N + GH ++ V P + S DR V +W L
Sbjct: 78 GGKDKTVVAYNWKTG-NVVKRFKGHEHEITKVACIPKSSQ--FFSASRDRMVMMWDLHGS 134
Query: 538 KLKINHL-GHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALC 365
L GH+ + + VSPD S +G +D +LWD+ G+ + +++T LC
Sbjct: 135 SQPRQQLCGHAMVVTGLAVSPDSSQLCTGSRDNTLLLWDVVTGQSVERASVSRNVVTHLC 194
Query: 364 FSPNR-YWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTS-KTDPPQCLSLAWSTDGQ 191
+ P Y L + ++++WD ++ + QT D +C+S + G+
Sbjct: 195 WVPREPYILQTSEDKTLRLWDSRGLQVAHMFPAKQHIQTYCEVSVDGHKCISCSNGFGGE 254
Score = 44.4 bits (100), Expect = 4e-04
Identities = 34/125 (27%), Positives = 55/125 (44%), Gaps = 3/125 (2%)
Frame = -2
Query: 646 HSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSL 467
H D VS V + N + + VS G D+TV ++ + GH + V P S
Sbjct: 60 HMDTVSVVA-ALN--SDLCVSGGKDKTVVAYNWKTGNVVKRFKGHEHEITKVACIPKSSQ 116
Query: 466 CASGGKDMKAMLWDLNDGK--HLHTLDHNDIITALCFSPNRYWLC-AAFGPSIKIWDLES 296
S +D M+WDL+ H ++T L SP+ LC + ++ +WD+ +
Sbjct: 117 FFSASRDRMVMMWDLHGSSQPRQQLCGHAMVVTGLAVSPDSSQLCTGSRDNTLLLWDVVT 176
Query: 295 KEMVE 281
+ VE
Sbjct: 177 GQSVE 181
Score = 36.3 bits (80), Expect = 0.11
Identities = 29/125 (23%), Positives = 51/125 (40%), Gaps = 4/125 (3%)
Frame = -2
Query: 505 YLNTVTV--SPDGSLCASGGKDMKAMLWDLNDGKHLHTLD--HNDIITALCFSPNRYWLC 338
+++TV+V + + LC SGGKD + ++ G + ++I C + +
Sbjct: 60 HMDTVSVVAALNSDLCVSGGKDKTVVAYNWKTGNVVKRFKGHEHEITKVACIPKSSQFFS 119
Query: 337 AAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTI 158
A+ + +WDL + R ++ LA S D L G DNT+
Sbjct: 120 ASRDRMVMMWDLHGSS---QPRQQLCGHAMV-------VTGLAVSPDSSQLCTGSRDNTL 169
Query: 157 RVWQV 143
+W V
Sbjct: 170 LLWDV 174
Score = 34.7 bits (76), Expect = 0.34
Identities = 38/155 (24%), Positives = 68/155 (43%), Gaps = 14/155 (9%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
GSRD T+ LW+ + + + + V+ + + P P I+ D+T+++W
Sbjct: 163 GSRDNTLLLWDVVTG-QSVERASVSRNVVTHLCWVPRE--PYILQTSEDKTLRLWDSRG- 218
Query: 538 KLKINHLGHSG-YLNTVT-VSPDGSLCAS-----GGKDMKAMLWDLNDGKH--LHTLDHN 386
L++ H+ + ++ T VS DG C S GG+ +A LWDL ++ H
Sbjct: 219 -LQVAHMFPAKQHIQTYCEVSVDGHKCISCSNGFGGEGCEATLWDLRQTRNRICEYKGHF 277
Query: 385 DIITALCFSPNRYWLCAAFGPS-----IKIWDLES 296
+ + F P L S +KIW+ ++
Sbjct: 278 QTVASCVFLPRALALMPLIATSSHDCKVKIWNQDT 312
>AL449305-1|CAI10961.1| 367|Homo sapiens WD repeat domain 31
protein.
Length = 367
Score = 54.8 bits (126), Expect = 3e-07
Identities = 43/180 (23%), Positives = 76/180 (42%), Gaps = 4/180 (2%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
G +DKT+ +N + GH ++ V P + S DR V +W L
Sbjct: 79 GGKDKTVVAYNWKTG-NVVKRFKGHEHEITKVACIPKSSQ--FFSASRDRMVMMWDLHGS 135
Query: 538 KLKINHL-GHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALC 365
L GH+ + + VSPD S +G +D +LWD+ G+ + +++T LC
Sbjct: 136 SQPRQQLCGHAMVVTGLAVSPDSSQLCTGSRDNTLLLWDVVTGQSVERASVSRNVVTHLC 195
Query: 364 FSPNR-YWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTS-KTDPPQCLSLAWSTDGQ 191
+ P Y L + ++++WD ++ + QT D +C+S + G+
Sbjct: 196 WVPREPYILQTSEDKTLRLWDSRGLQVAHMFPAKQHIQTYCEVSVDGHKCISCSNGFGGE 255
Score = 44.4 bits (100), Expect = 4e-04
Identities = 34/125 (27%), Positives = 55/125 (44%), Gaps = 3/125 (2%)
Frame = -2
Query: 646 HSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSL 467
H D VS V + N + + VS G D+TV ++ + GH + V P S
Sbjct: 61 HMDTVSVVA-ALN--SDLCVSGGKDKTVVAYNWKTGNVVKRFKGHEHEITKVACIPKSSQ 117
Query: 466 CASGGKDMKAMLWDLNDGK--HLHTLDHNDIITALCFSPNRYWLC-AAFGPSIKIWDLES 296
S +D M+WDL+ H ++T L SP+ LC + ++ +WD+ +
Sbjct: 118 FFSASRDRMVMMWDLHGSSQPRQQLCGHAMVVTGLAVSPDSSQLCTGSRDNTLLLWDVVT 177
Query: 295 KEMVE 281
+ VE
Sbjct: 178 GQSVE 182
Score = 36.3 bits (80), Expect = 0.11
Identities = 29/125 (23%), Positives = 51/125 (40%), Gaps = 4/125 (3%)
Frame = -2
Query: 505 YLNTVTV--SPDGSLCASGGKDMKAMLWDLNDGKHLHTLD--HNDIITALCFSPNRYWLC 338
+++TV+V + + LC SGGKD + ++ G + ++I C + +
Sbjct: 61 HMDTVSVVAALNSDLCVSGGKDKTVVAYNWKTGNVVKRFKGHEHEITKVACIPKSSQFFS 120
Query: 337 AAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTI 158
A+ + +WDL + R ++ LA S D L G DNT+
Sbjct: 121 ASRDRMVMMWDLHGSS---QPRQQLCGHAMV-------VTGLAVSPDSSQLCTGSRDNTL 170
Query: 157 RVWQV 143
+W V
Sbjct: 171 LLWDV 175
Score = 34.7 bits (76), Expect = 0.34
Identities = 38/155 (24%), Positives = 68/155 (43%), Gaps = 14/155 (9%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
GSRD T+ LW+ + + + + V+ + + P P I+ D+T+++W
Sbjct: 164 GSRDNTLLLWDVVTG-QSVERASVSRNVVTHLCWVPRE--PYILQTSEDKTLRLWDSRG- 219
Query: 538 KLKINHLGHSG-YLNTVT-VSPDGSLCAS-----GGKDMKAMLWDLNDGKH--LHTLDHN 386
L++ H+ + ++ T VS DG C S GG+ +A LWDL ++ H
Sbjct: 220 -LQVAHMFPAKQHIQTYCEVSVDGHKCISCSNGFGGEGCEATLWDLRQTRNRICEYKGHF 278
Query: 385 DIITALCFSPNRYWLCAAFGPS-----IKIWDLES 296
+ + F P L S +KIW+ ++
Sbjct: 279 QTVASCVFLPRALALMPLIATSSHDCKVKIWNQDT 313
>AL137066-1|CAH70096.1| 367|Homo sapiens WD repeat domain 31
protein.
Length = 367
Score = 54.8 bits (126), Expect = 3e-07
Identities = 43/180 (23%), Positives = 76/180 (42%), Gaps = 4/180 (2%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
G +DKT+ +N + GH ++ V P + S DR V +W L
Sbjct: 79 GGKDKTVVAYNWKTG-NVVKRFKGHEHEITKVACIPKSSQ--FFSASRDRMVMMWDLHGS 135
Query: 538 KLKINHL-GHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALC 365
L GH+ + + VSPD S +G +D +LWD+ G+ + +++T LC
Sbjct: 136 SQPRQQLCGHAMVVTGLAVSPDSSQLCTGSRDNTLLLWDVVTGQSVERASVSRNVVTHLC 195
Query: 364 FSPNR-YWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTS-KTDPPQCLSLAWSTDGQ 191
+ P Y L + ++++WD ++ + QT D +C+S + G+
Sbjct: 196 WVPREPYILQTSEDKTLRLWDSRGLQVAHMFPAKQHIQTYCEVSVDGHKCISCSNGFGGE 255
Score = 44.4 bits (100), Expect = 4e-04
Identities = 34/125 (27%), Positives = 55/125 (44%), Gaps = 3/125 (2%)
Frame = -2
Query: 646 HSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSL 467
H D VS V + N + + VS G D+TV ++ + GH + V P S
Sbjct: 61 HMDTVSVVA-ALN--SDLCVSGGKDKTVVAYNWKTGNVVKRFKGHEHEITKVACIPKSSQ 117
Query: 466 CASGGKDMKAMLWDLNDGK--HLHTLDHNDIITALCFSPNRYWLC-AAFGPSIKIWDLES 296
S +D M+WDL+ H ++T L SP+ LC + ++ +WD+ +
Sbjct: 118 FFSASRDRMVMMWDLHGSSQPRQQLCGHAMVVTGLAVSPDSSQLCTGSRDNTLLLWDVVT 177
Query: 295 KEMVE 281
+ VE
Sbjct: 178 GQSVE 182
Score = 36.3 bits (80), Expect = 0.11
Identities = 29/125 (23%), Positives = 51/125 (40%), Gaps = 4/125 (3%)
Frame = -2
Query: 505 YLNTVTV--SPDGSLCASGGKDMKAMLWDLNDGKHLHTLD--HNDIITALCFSPNRYWLC 338
+++TV+V + + LC SGGKD + ++ G + ++I C + +
Sbjct: 61 HMDTVSVVAALNSDLCVSGGKDKTVVAYNWKTGNVVKRFKGHEHEITKVACIPKSSQFFS 120
Query: 337 AAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTI 158
A+ + +WDL + R ++ LA S D L G DNT+
Sbjct: 121 ASRDRMVMMWDLHGSS---QPRQQLCGHAMV-------VTGLAVSPDSSQLCTGSRDNTL 170
Query: 157 RVWQV 143
+W V
Sbjct: 171 LLWDV 175
Score = 34.7 bits (76), Expect = 0.34
Identities = 38/155 (24%), Positives = 68/155 (43%), Gaps = 14/155 (9%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
GSRD T+ LW+ + + + + V+ + + P P I+ D+T+++W
Sbjct: 164 GSRDNTLLLWDVVTG-QSVERASVSRNVVTHLCWVPRE--PYILQTSEDKTLRLWDSRG- 219
Query: 538 KLKINHLGHSG-YLNTVT-VSPDGSLCAS-----GGKDMKAMLWDLNDGKH--LHTLDHN 386
L++ H+ + ++ T VS DG C S GG+ +A LWDL ++ H
Sbjct: 220 -LQVAHMFPAKQHIQTYCEVSVDGHKCISCSNGFGGEGCEATLWDLRQTRNRICEYKGHF 278
Query: 385 DIITALCFSPNRYWLCAAFGPS-----IKIWDLES 296
+ + F P L S +KIW+ ++
Sbjct: 279 QTVASCVFLPRALALMPLIATSSHDCKVKIWNQDT 313
>AK093240-1|BAC04106.1| 367|Homo sapiens protein ( Homo sapiens
cDNA FLJ35921 fis, clone TESTI2010617, highly similar to
Mus musculus spermatid WD-repeat protein mRNA. ).
Length = 367
Score = 54.8 bits (126), Expect = 3e-07
Identities = 43/180 (23%), Positives = 76/180 (42%), Gaps = 4/180 (2%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
G +DKT+ +N + GH ++ V P + S DR V +W L
Sbjct: 79 GGKDKTVVAYNWKTG-NVVKRFKGHEHEITKVACIPKSSQ--FFSASRDRMVMMWDLHGS 135
Query: 538 KLKINHL-GHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLD-HNDIITALC 365
L GH+ + + VSPD S +G +D +LWD+ G+ + +++T LC
Sbjct: 136 SQPRQQLCGHAMVVTGLAVSPDSSQLCTGSRDNTLLLWDVVTGQSVERASVSRNVVTHLC 195
Query: 364 FSPNR-YWLCAAFGPSIKIWDLESKEMVEELRPEIINQTQTS-KTDPPQCLSLAWSTDGQ 191
+ P Y L + ++++WD ++ + QT D +C+S + G+
Sbjct: 196 WVPREPYILQTSEDKTLRLWDSRGLQVAHMFPAKQHIQTYCEVSVDGHKCISCSNGFGGE 255
Score = 44.4 bits (100), Expect = 4e-04
Identities = 34/125 (27%), Positives = 55/125 (44%), Gaps = 3/125 (2%)
Frame = -2
Query: 646 HSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSL 467
H D VS V + N + + VS G D+TV ++ + GH + V P S
Sbjct: 61 HMDTVSVVA-ALN--SDLCVSGGKDKTVVAYNWKTGNVVKRFKGHEHEITKVACIPKSSQ 117
Query: 466 CASGGKDMKAMLWDLNDGK--HLHTLDHNDIITALCFSPNRYWLC-AAFGPSIKIWDLES 296
S +D M+WDL+ H ++T L SP+ LC + ++ +WD+ +
Sbjct: 118 FFSASRDRMVMMWDLHGSSQPRQQLCGHAMVVTGLAVSPDSSQLCTGSRDNTLLLWDVVT 177
Query: 295 KEMVE 281
+ VE
Sbjct: 178 GQSVE 182
Score = 36.3 bits (80), Expect = 0.11
Identities = 29/125 (23%), Positives = 51/125 (40%), Gaps = 4/125 (3%)
Frame = -2
Query: 505 YLNTVTV--SPDGSLCASGGKDMKAMLWDLNDGKHLHTLD--HNDIITALCFSPNRYWLC 338
+++TV+V + + LC SGGKD + ++ G + ++I C + +
Sbjct: 61 HMDTVSVVAALNSDLCVSGGKDKTVVAYNWKTGNVVKRFKGHEHEITKVACIPKSSQFFS 120
Query: 337 AAFGPSIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTI 158
A+ + +WDL + R ++ LA S D L G DNT+
Sbjct: 121 ASRDRMVMMWDLHGSS---QPRQQLCGHAMV-------VTGLAVSPDSSQLCTGSRDNTL 170
Query: 157 RVWQV 143
+W V
Sbjct: 171 LLWDV 175
Score = 34.7 bits (76), Expect = 0.34
Identities = 38/155 (24%), Positives = 68/155 (43%), Gaps = 14/155 (9%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNC 539
GSRD T+ LW+ + + + + V+ + + P P I+ D+T+++W
Sbjct: 164 GSRDNTLLLWDVVTG-QSVERASVSRNVVTHLCWVPRE--PYILQTSEDKTLRLWDSRG- 219
Query: 538 KLKINHLGHSG-YLNTVT-VSPDGSLCAS-----GGKDMKAMLWDLNDGKH--LHTLDHN 386
L++ H+ + ++ T VS DG C S GG+ +A LWDL ++ H
Sbjct: 220 -LQVAHMFPAKQHIQTYCEVSVDGHKCISCSNGFGGEGCEATLWDLRQTRNRICEYKGHF 278
Query: 385 DIITALCFSPNRYWLCAAFGPS-----IKIWDLES 296
+ + F P L S +KIW+ ++
Sbjct: 279 QTVASCVFLPRALALMPLIATSSHDCKVKIWNQDT 313
>BC113421-1|AAI13422.1| 514|Homo sapiens transducin (beta)-like
1X-linked receptor 1 protein.
Length = 514
Score = 54.0 bits (124), Expect = 5e-07
Identities = 43/169 (25%), Positives = 69/169 (40%), Gaps = 11/169 (6%)
Frame = -2
Query: 604 ANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWD 425
+N SC D + V L + GH+ +N + P G+L AS DM +W
Sbjct: 318 SNNTFASCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLKIWS 377
Query: 424 LNDGKHLHTLD-HNDIITALCFSP----------NRYWLCAAFGPSIKIWDLESKEMVEE 278
+ +H L HN I + +SP N A+F ++++WD++
Sbjct: 378 MKQDNCVHDLQAHNKEIYTIKWSPTGPGTNNPNANLMLASASFDSTVRLWDVDR------ 431
Query: 277 LRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQVSISA 131
I T T +P S+A+S DG+ L +G D + +W A
Sbjct: 432 ---GICIHTLTKHQEP--VYSVAFSPDGRYLASGSFDKCVHIWNTQTGA 475
Score = 48.0 bits (109), Expect = 3e-05
Identities = 32/127 (25%), Positives = 59/127 (46%), Gaps = 8/127 (6%)
Frame = -2
Query: 715 SRDKTIKLWNTLAE-CKYTIQDDGHSDWVSCVRFSPN-------HANPIIVSCGWDRTVK 560
S D T+K+W+ + C + +Q H+ + +++SP +AN ++ S +D TV+
Sbjct: 368 SDDMTLKIWSMKQDNCVHDLQ--AHNKEIYTIKWSPTGPGTNNPNANLMLASASFDSTVR 425
Query: 559 VWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDI 380
+W + H + +V SPDG ASG D +W+ G +H+
Sbjct: 426 LWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQTGALVHSYRGTGG 485
Query: 379 ITALCFS 359
I +C++
Sbjct: 486 IFEVCWN 492
>AK022956-1|BAB14331.1| 514|Homo sapiens protein ( Homo sapiens
cDNA FLJ12894 fis, clone NT2RP2004170, moderately
similar to Homo sapiens mRNA for transducin (beta) like
1 protein. ).
Length = 514
Score = 54.0 bits (124), Expect = 5e-07
Identities = 43/169 (25%), Positives = 69/169 (40%), Gaps = 11/169 (6%)
Frame = -2
Query: 604 ANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWD 425
+N SC D + V L + GH+ +N + P G+L AS DM +W
Sbjct: 318 SNNTFASCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLKIWS 377
Query: 424 LNDGKHLHTLD-HNDIITALCFSP----------NRYWLCAAFGPSIKIWDLESKEMVEE 278
+ +H L HN I + +SP N A+F ++++WD++
Sbjct: 378 MKQDNCVHDLQAHNKEIYTIKWSPTGPGTNNPNANLMLASASFDSTVRLWDVDR------ 431
Query: 277 LRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQVSISA 131
I T T +P S+A+S DG+ L +G D + +W A
Sbjct: 432 ---GICIHTLTKHQEP--VYSVAFSPDGRYLASGSFDKCVHIWNTQTGA 475
Score = 48.0 bits (109), Expect = 3e-05
Identities = 32/127 (25%), Positives = 59/127 (46%), Gaps = 8/127 (6%)
Frame = -2
Query: 715 SRDKTIKLWNTLAE-CKYTIQDDGHSDWVSCVRFSPN-------HANPIIVSCGWDRTVK 560
S D T+K+W+ + C + +Q H+ + +++SP +AN ++ S +D TV+
Sbjct: 368 SDDMTLKIWSMKQDNCVHDLQ--AHNKEIYTIKWSPTGPGTNNPNANLMLASASFDSTVR 425
Query: 559 VWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDI 380
+W + H + +V SPDG ASG D +W+ G +H+
Sbjct: 426 LWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQTGALVHSYRGTGG 485
Query: 379 ITALCFS 359
I +C++
Sbjct: 486 IFEVCWN 492
>AF314544-1|AAK00301.1| 514|Homo sapiens nuclear receptor
co-repressor/HDAC3 complex subunit TBLR1 protein.
Length = 514
Score = 54.0 bits (124), Expect = 5e-07
Identities = 43/169 (25%), Positives = 69/169 (40%), Gaps = 11/169 (6%)
Frame = -2
Query: 604 ANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWD 425
+N SC D + V L + GH+ +N + P G+L AS DM +W
Sbjct: 318 SNNTFASCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLKIWS 377
Query: 424 LNDGKHLHTLD-HNDIITALCFSP----------NRYWLCAAFGPSIKIWDLESKEMVEE 278
+ +H L HN I + +SP N A+F ++++WD++
Sbjct: 378 MKQDNCVHDLQAHNKEIYTIKWSPTGPGTNNPNANLMLASASFDSTVRLWDVDR------ 431
Query: 277 LRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQVSISA 131
I T T +P S+A+S DG+ L +G D + +W A
Sbjct: 432 ---GICIHTLTKHQEP--VYSVAFSPDGRYLASGSFDKCVHIWNTQTGA 475
Score = 48.0 bits (109), Expect = 3e-05
Identities = 32/127 (25%), Positives = 59/127 (46%), Gaps = 8/127 (6%)
Frame = -2
Query: 715 SRDKTIKLWNTLAE-CKYTIQDDGHSDWVSCVRFSPN-------HANPIIVSCGWDRTVK 560
S D T+K+W+ + C + +Q H+ + +++SP +AN ++ S +D TV+
Sbjct: 368 SDDMTLKIWSMKQDNCVHDLQ--AHNKEIYTIKWSPTGPGTNNPNANLMLASASFDSTVR 425
Query: 559 VWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDI 380
+W + H + +V SPDG ASG D +W+ G +H+
Sbjct: 426 LWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQTGALVHSYRGTGG 485
Query: 379 ITALCFS 359
I +C++
Sbjct: 486 IFEVCWN 492
>AF268193-1|AAG44736.1| 514|Homo sapiens IRA1 protein.
Length = 514
Score = 54.0 bits (124), Expect = 5e-07
Identities = 43/169 (25%), Positives = 69/169 (40%), Gaps = 11/169 (6%)
Frame = -2
Query: 604 ANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWD 425
+N SC D + V L + GH+ +N + P G+L AS DM +W
Sbjct: 318 SNNTFASCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLKIWS 377
Query: 424 LNDGKHLHTL-DHNDIITALCFSP----------NRYWLCAAFGPSIKIWDLESKEMVEE 278
+ +H L HN I + +SP N A+F ++++WD++
Sbjct: 378 MKQDNCVHDLQQHNKEIYTIKWSPTGPGTNNPNANLMLASASFDSTVRLWDVDR------ 431
Query: 277 LRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQVSISA 131
I T T +P S+A+S DG+ L +G D + +W A
Sbjct: 432 ---GICIHTLTKHQEP--VYSVAFSPDGRYLASGSFDKCVHIWNTQTGA 475
Score = 48.0 bits (109), Expect = 3e-05
Identities = 32/127 (25%), Positives = 59/127 (46%), Gaps = 8/127 (6%)
Frame = -2
Query: 715 SRDKTIKLWNTLAE-CKYTIQDDGHSDWVSCVRFSPN-------HANPIIVSCGWDRTVK 560
S D T+K+W+ + C + +Q H+ + +++SP +AN ++ S +D TV+
Sbjct: 368 SDDMTLKIWSMKQDNCVHDLQQ--HNKEIYTIKWSPTGPGTNNPNANLMLASASFDSTVR 425
Query: 559 VWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDI 380
+W + H + +V SPDG ASG D +W+ G +H+
Sbjct: 426 LWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQTGALVHSYRGTGG 485
Query: 379 ITALCFS 359
I +C++
Sbjct: 486 IFEVCWN 492
>AC006011-2|AAX82033.1| 1336|Homo sapiens unknown protein.
Length = 1336
Score = 54.0 bits (124), Expect = 5e-07
Identities = 46/175 (26%), Positives = 74/175 (42%), Gaps = 5/175 (2%)
Frame = -2
Query: 646 HSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSL 467
H + + FSP +C D TV++W C + GH + V P L
Sbjct: 201 HKEAIREASFSPTDNK--FATCSDDGTVRIWDFLRCHEERILRGHGADVKCVDWHPTKGL 258
Query: 466 CASGGKDMKAML--WDLNDGKHLHTLD-HNDIITALCFSPNRYWLCAAFGPSI-KIWDLE 299
SG KD + + WD G+ L TL H + + + + N WL A + K++D+
Sbjct: 259 VVSGSKDSQQPIKFWDPKTGQSLATLHAHKNTVMEVKLNLNGNWLLTASRDHLCKLFDI- 317
Query: 298 SKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFA-GYSDNTIRVWQVSI 137
+ + EEL Q + + ++AW + LFA G SD ++ W V +
Sbjct: 318 -RNLKEEL--------QVFRGHKKEATAVAWHPVHEGLFASGGSDGSLLFWHVGV 363
Score = 37.9 bits (84), Expect = 0.036
Identities = 47/194 (24%), Positives = 80/194 (41%), Gaps = 5/194 (2%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWH-LTNC 539
S D T+++W+ L C GH V CV + P + S + +K W T
Sbjct: 221 SDDGTVRIWDFL-RCHEERILRGHGADVKCVDWHPTKGLVVSGSKDSQQPIKFWDPKTGQ 279
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKH-LHTL-DHNDIITALC 365
L H H + V ++ +G+ + +D L+D+ + K L H TA+
Sbjct: 280 SLATLH-AHKNTVMEVKLNLNGNWLLTASRDHLCKLFDIRNLKEELQVFRGHKKEATAVA 338
Query: 364 FSPNRYWLCAAFGP--SIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQ 191
+ P L A+ G S+ W + ++ V + E+ ++ SLAW G
Sbjct: 339 WHPVHEGLFASGGSDGSLLFWHVGVEKEVGGM--EMAHEGMI--------WSLAWHPLGH 388
Query: 190 TLFAGYSDNTIRVW 149
L +G +D+T + W
Sbjct: 389 ILCSGSNDHTSKFW 402
>AB044749-1|BAB32435.1| 1336|Homo sapiens WDC146 protein.
Length = 1336
Score = 54.0 bits (124), Expect = 5e-07
Identities = 46/175 (26%), Positives = 74/175 (42%), Gaps = 5/175 (2%)
Frame = -2
Query: 646 HSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSL 467
H + + FSP +C D TV++W C + GH + V P L
Sbjct: 201 HKEAIREASFSPTDNK--FATCSDDGTVRIWDFLRCHEERILRGHGADVKCVDWHPTKGL 258
Query: 466 CASGGKDMKAML--WDLNDGKHLHTLD-HNDIITALCFSPNRYWLCAAFGPSI-KIWDLE 299
SG KD + + WD G+ L TL H + + + + N WL A + K++D+
Sbjct: 259 VVSGSKDSQQPIKFWDPKTGQSLATLHAHKNTVMEVKLNLNGNWLLTASRDHLCKLFDI- 317
Query: 298 SKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFA-GYSDNTIRVWQVSI 137
+ + EEL Q + + ++AW + LFA G SD ++ W V +
Sbjct: 318 -RNLKEEL--------QVFRGHKKEATAVAWHPVHEGLFASGGSDGSLLFWHVGV 363
Score = 37.9 bits (84), Expect = 0.036
Identities = 47/194 (24%), Positives = 80/194 (41%), Gaps = 5/194 (2%)
Frame = -2
Query: 715 SRDKTIKLWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWH-LTNC 539
S D T+++W+ L C GH V CV + P + S + +K W T
Sbjct: 221 SDDGTVRIWDFL-RCHEERILRGHGADVKCVDWHPTKGLVVSGSKDSQQPIKFWDPKTGQ 279
Query: 538 KLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKH-LHTL-DHNDIITALC 365
L H H + V ++ +G+ + +D L+D+ + K L H TA+
Sbjct: 280 SLATLH-AHKNTVMEVKLNLNGNWLLTASRDHLCKLFDIRNLKEELQVFRGHKKEATAVA 338
Query: 364 FSPNRYWLCAAFGP--SIKIWDLESKEMVEELRPEIINQTQTSKTDPPQCLSLAWSTDGQ 191
+ P L A+ G S+ W + ++ V + E+ ++ SLAW G
Sbjct: 339 WHPVHEGLFASGGSDGSLLFWHVGVEKEVGGM--EMAHEGMI--------WSLAWHPLGH 388
Query: 190 TLFAGYSDNTIRVW 149
L +G +D+T + W
Sbjct: 389 ILCSGSNDHTSKFW 402
>Y12781-1|CAA73319.1| 577|Homo sapiens transducin (beta) like 1
protein protein.
Length = 577
Score = 53.6 bits (123), Expect = 7e-07
Identities = 43/163 (26%), Positives = 67/163 (41%), Gaps = 12/163 (7%)
Frame = -2
Query: 601 NPIIVSCGWDRTVKVWHLTNCKLKINHL-GHSGYLNTVTVSPDGSLCASGGKDMKAMLWD 425
N SC D + V L C + GH+ +N + P G L AS DM +W
Sbjct: 382 NTTFASCSTDMCIHVCRL-GCDRPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWS 440
Query: 424 LNDGKHLHTLD-HNDIITALCFSP----------NRYWLCAAFGPSIKIWDLESKEMVEE 278
+ +H L HN I + +SP N A+F ++++WD+E
Sbjct: 441 MKQEVCIHDLQAHNKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWDIER------ 494
Query: 277 LRPEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVW 149
+ T T +P S+A+S DG+ L +G D + +W
Sbjct: 495 ---GVCTHTLTKHQEP--VYSVAFSPDGKYLASGSFDKCVHIW 532
Score = 50.4 bits (115), Expect = 6e-06
Identities = 32/127 (25%), Positives = 59/127 (46%), Gaps = 8/127 (6%)
Frame = -2
Query: 715 SRDKTIKLWNTLAE-CKYTIQDDGHSDWVSCVRFSPN-------HANPIIVSCGWDRTVK 560
S D T+K+W+ E C + +Q H+ + +++SP ++N ++ S +D TV+
Sbjct: 431 SDDMTLKIWSMKQEVCIHDLQ--AHNKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVR 488
Query: 559 VWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHTLDHNDI 380
+W + H + +V SPDG ASG D +W+ G +H+
Sbjct: 489 LWDIERGVCTHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNTQSGNLVHSYRGTGG 548
Query: 379 ITALCFS 359
I +C++
Sbjct: 549 IFEVCWN 555
>X95263-1|CAA64560.1| 919|Homo sapiens PWP2 protein.
Length = 919
Score = 53.6 bits (123), Expect = 7e-07
Identities = 38/144 (26%), Positives = 70/144 (48%), Gaps = 5/144 (3%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAE-CKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
G D +K+WNTL+ C T + HS V+ V F+ ++V+ D TV+ + L
Sbjct: 391 GGDDGKVKVWNTLSGFCFVTFTE--HSSGVTGVTFTA--TGYVVVTSSMDGTVRAFDLHR 446
Query: 541 CK-LKINHLGHSGYLNTVTVSPDGSLCASGGKD-MKAMLWDLNDGKHLHTLD-HNDIITA 371
+ + + V V G + ++G +D + +W + G+ L L H I+
Sbjct: 447 YRNFRTFTSPRPTQFSCVAVDASGEIVSAGAQDSFEIFVWSMQTGRLLDVLSGHEGPISG 506
Query: 370 LCFSPNRYWLC-AAFGPSIKIWDL 302
LCF+P + L A++ ++++WD+
Sbjct: 507 LCFNPMKSVLASASWDKTVRLWDM 530
Score = 39.9 bits (89), Expect = 0.009
Identities = 40/163 (24%), Positives = 65/163 (39%), Gaps = 13/163 (7%)
Frame = -2
Query: 592 IVSCGWDRTVK--VWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLN 419
IVS G + + VW + +L GH G ++ + +P S+ AS D LWD+
Sbjct: 472 IVSAGAQDSFEIFVWSMQTGRLLDVLSGHEGPISGLCFNPMKSVLASASWDKTVRLWDMF 531
Query: 418 DG-KHLHTLDHNDIITALCFSPNRYWLC-AAFGPSIKIWD---------LESKEMVEELR 272
D + TL A+ F P+ L A I WD +E + ++ R
Sbjct: 532 DSWRTKETLALTSDALAVTFRPDGAELAVATLNSQITFWDPENAVQTGSIEGRHDLKTGR 591
Query: 271 PEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQV 143
E+ T +L +S DG ++ AG + ++ V
Sbjct: 592 KELDKITAKHAAKGKAFTALCYSADGHSILAGGMSKFVCIYHV 634
Score = 37.5 bits (83), Expect = 0.048
Identities = 23/100 (23%), Positives = 43/100 (43%), Gaps = 2/100 (2%)
Frame = -2
Query: 595 IIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLND 416
I C + VW + + GH + + SPDG +GG D K +W+
Sbjct: 345 IAFGCSGLGQLLVWEWQSESYVLKQQGHFNSMVALAYSPDGQYIVTGGDDGKVKVWNTLS 404
Query: 415 GKHLHTL-DHNDIITALCFSPNRY-WLCAAFGPSIKIWDL 302
G T +H+ +T + F+ Y + ++ +++ +DL
Sbjct: 405 GFCFVTFTEHSSGVTGVTFTATGYVVVTSSMDGTVRAFDL 444
Score = 36.7 bits (81), Expect = 0.084
Identities = 20/75 (26%), Positives = 35/75 (46%)
Frame = -2
Query: 649 GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGS 470
GH +S + F+P + ++ S WD+TV++W + + L + VT PDG+
Sbjct: 499 GHEGPISGLCFNPMKS--VLASASWDKTVRLWDMFDSWRTKETLALTSDALAVTFRPDGA 556
Query: 469 LCASGGKDMKAMLWD 425
A + + WD
Sbjct: 557 ELAVATLNSQITFWD 571
Score = 36.3 bits (80), Expect = 0.11
Identities = 24/99 (24%), Positives = 45/99 (45%)
Frame = -2
Query: 694 LWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLG 515
+W +E Y ++ GH + + + +SP+ IV+ G D VKVW+ + +
Sbjct: 357 VWEWQSE-SYVLKQQGHFNSMVALAYSPD--GQYIVTGGDDGKVKVWNTLSGFCFVTFTE 413
Query: 514 HSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHT 398
HS + VT + G + + D +DL+ ++ T
Sbjct: 414 HSSGVTGVTFTATGYVVVTSSMDGTVRAFDLHRYRNFRT 452
>U56089-1|AAC50905.1| 919|Homo sapiens periodic tryptophan protein
2 protein.
Length = 919
Score = 53.6 bits (123), Expect = 7e-07
Identities = 38/144 (26%), Positives = 70/144 (48%), Gaps = 5/144 (3%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAE-CKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
G D +K+WNTL+ C T + HS V+ V F+ ++V+ D TV+ + L
Sbjct: 391 GGDDGKVKVWNTLSGFCFVTFTE--HSSGVTGVTFTA--TGYVVVTSSMDGTVRAFDLHR 446
Query: 541 CK-LKINHLGHSGYLNTVTVSPDGSLCASGGKD-MKAMLWDLNDGKHLHTLD-HNDIITA 371
+ + + V V G + ++G +D + +W + G+ L L H I+
Sbjct: 447 YRNFRTFTSPRPTQFSCVAVDASGEIVSAGAQDSFEIFVWSMQTGRLLDVLSGHEGPISG 506
Query: 370 LCFSPNRYWLC-AAFGPSIKIWDL 302
LCF+P + L A++ ++++WD+
Sbjct: 507 LCFNPMKSVLASASWDKTVRLWDM 530
Score = 39.9 bits (89), Expect = 0.009
Identities = 40/163 (24%), Positives = 65/163 (39%), Gaps = 13/163 (7%)
Frame = -2
Query: 592 IVSCGWDRTVK--VWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLN 419
IVS G + + VW + +L GH G ++ + +P S+ AS D LWD+
Sbjct: 472 IVSAGAQDSFEIFVWSMQTGRLLDVLSGHEGPISGLCFNPMKSVLASASWDKTVRLWDMF 531
Query: 418 DG-KHLHTLDHNDIITALCFSPNRYWLC-AAFGPSIKIWD---------LESKEMVEELR 272
D + TL A+ F P+ L A I WD +E + ++ R
Sbjct: 532 DSWRTKETLALTSDALAVTFRPDGAELAVATLNSQITFWDPENAVQTGSIEGRHDLKTGR 591
Query: 271 PEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQV 143
E+ T +L +S DG ++ AG + ++ V
Sbjct: 592 KELDKITAKHAAKGKAFTALCYSADGHSILAGGMSKFVCIYHV 634
Score = 37.5 bits (83), Expect = 0.048
Identities = 23/100 (23%), Positives = 43/100 (43%), Gaps = 2/100 (2%)
Frame = -2
Query: 595 IIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLND 416
I C + VW + + GH + + SPDG +GG D K +W+
Sbjct: 345 IAFGCSGLGQLLVWEWQSESYVLKQQGHFNSMVALAYSPDGQYIVTGGDDGKVKVWNTLS 404
Query: 415 GKHLHTL-DHNDIITALCFSPNRY-WLCAAFGPSIKIWDL 302
G T +H+ +T + F+ Y + ++ +++ +DL
Sbjct: 405 GFCFVTFTEHSSGVTGVTFTATGYVVVTSSMDGTVRAFDL 444
Score = 36.7 bits (81), Expect = 0.084
Identities = 20/75 (26%), Positives = 35/75 (46%)
Frame = -2
Query: 649 GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGS 470
GH +S + F+P + ++ S WD+TV++W + + L + VT PDG+
Sbjct: 499 GHEGPISGLCFNPMKS--VLASASWDKTVRLWDMFDSWRTKETLALTSDALAVTFRPDGA 556
Query: 469 LCASGGKDMKAMLWD 425
A + + WD
Sbjct: 557 ELAVATLNSQITFWD 571
Score = 36.3 bits (80), Expect = 0.11
Identities = 24/99 (24%), Positives = 45/99 (45%)
Frame = -2
Query: 694 LWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLG 515
+W +E Y ++ GH + + + +SP+ IV+ G D VKVW+ + +
Sbjct: 357 VWEWQSE-SYVLKQQGHFNSMVALAYSPD--GQYIVTGGDDGKVKVWNTLSGFCFVTFTE 413
Query: 514 HSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHT 398
HS + VT + G + + D +DL+ ++ T
Sbjct: 414 HSSGVTGVTFTATGYVVVTSSMDGTVRAFDLHRYRNFRT 452
>U56085-1|AAC50904.1| 919|Homo sapiens periodic tryptophan protein
2 protein.
Length = 919
Score = 53.6 bits (123), Expect = 7e-07
Identities = 38/144 (26%), Positives = 70/144 (48%), Gaps = 5/144 (3%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAE-CKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
G D +K+WNTL+ C T + HS V+ V F+ ++V+ D TV+ + L
Sbjct: 391 GGDDGKVKVWNTLSGFCFVTFTE--HSSGVTGVTFTA--TGYVVVTSSMDGTVRAFDLHR 446
Query: 541 CK-LKINHLGHSGYLNTVTVSPDGSLCASGGKD-MKAMLWDLNDGKHLHTLD-HNDIITA 371
+ + + V V G + ++G +D + +W + G+ L L H I+
Sbjct: 447 YRNFRTFTSPRPTQFSCVAVDASGEIVSAGAQDSFEIFVWSMQTGRLLDVLSGHEGPISG 506
Query: 370 LCFSPNRYWLC-AAFGPSIKIWDL 302
LCF+P + L A++ ++++WD+
Sbjct: 507 LCFNPMKSVLASASWDKTVRLWDM 530
Score = 39.9 bits (89), Expect = 0.009
Identities = 40/163 (24%), Positives = 65/163 (39%), Gaps = 13/163 (7%)
Frame = -2
Query: 592 IVSCGWDRTVK--VWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLN 419
IVS G + + VW + +L GH G ++ + +P S+ AS D LWD+
Sbjct: 472 IVSAGAQDSFEIFVWSMQTGRLLDVLSGHEGPISGLCFNPMKSVLASASWDKTVRLWDMF 531
Query: 418 DG-KHLHTLDHNDIITALCFSPNRYWLC-AAFGPSIKIWD---------LESKEMVEELR 272
D + TL A+ F P+ L A I WD +E + ++ R
Sbjct: 532 DSWRTKETLALTSDALAVTFRPDGAELAVATLNSQITFWDPENAVQTGSIEGRHDLKTGR 591
Query: 271 PEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQV 143
E+ T +L +S DG ++ AG + ++ V
Sbjct: 592 KELDKITAKHAAKGKAFTALCYSADGHSILAGGMSKFVCIYHV 634
Score = 37.5 bits (83), Expect = 0.048
Identities = 23/100 (23%), Positives = 43/100 (43%), Gaps = 2/100 (2%)
Frame = -2
Query: 595 IIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLND 416
I C + VW + + GH + + SPDG +GG D K +W+
Sbjct: 345 IAFGCSGLGQLLVWEWQSESYVLKQQGHFNSMVALAYSPDGQYIVTGGDDGKVKVWNTLS 404
Query: 415 GKHLHTL-DHNDIITALCFSPNRY-WLCAAFGPSIKIWDL 302
G T +H+ +T + F+ Y + ++ +++ +DL
Sbjct: 405 GFCFVTFTEHSSGVTGVTFTATGYVVVTSSMDGTVRAFDL 444
Score = 36.7 bits (81), Expect = 0.084
Identities = 20/75 (26%), Positives = 35/75 (46%)
Frame = -2
Query: 649 GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGS 470
GH +S + F+P + ++ S WD+TV++W + + L + VT PDG+
Sbjct: 499 GHEGPISGLCFNPMKS--VLASASWDKTVRLWDMFDSWRTKETLALTSDALAVTFRPDGA 556
Query: 469 LCASGGKDMKAMLWD 425
A + + WD
Sbjct: 557 ELAVATLNSQITFWD 571
Score = 36.3 bits (80), Expect = 0.11
Identities = 24/99 (24%), Positives = 45/99 (45%)
Frame = -2
Query: 694 LWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLG 515
+W +E Y ++ GH + + + +SP+ IV+ G D VKVW+ + +
Sbjct: 357 VWEWQSE-SYVLKQQGHFNSMVALAYSPD--GQYIVTGGDDGKVKVWNTLSGFCFVTFTE 413
Query: 514 HSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHT 398
HS + VT + G + + D +DL+ ++ T
Sbjct: 414 HSSGVTGVTFTATGYVVVTSSMDGTVRAFDLHRYRNFRT 452
>U53346-1|AAB08084.1| 919|Homo sapiens PWP2H protein protein.
Length = 919
Score = 53.6 bits (123), Expect = 7e-07
Identities = 38/144 (26%), Positives = 70/144 (48%), Gaps = 5/144 (3%)
Frame = -2
Query: 718 GSRDKTIKLWNTLAE-CKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTN 542
G D +K+WNTL+ C T + HS V+ V F+ ++V+ D TV+ + L
Sbjct: 391 GGDDGKVKVWNTLSGFCFVTFTE--HSSGVTGVTFTA--TGYVVVTSSMDGTVRAFDLHR 446
Query: 541 CK-LKINHLGHSGYLNTVTVSPDGSLCASGGKD-MKAMLWDLNDGKHLHTLD-HNDIITA 371
+ + + V V G + ++G +D + +W + G+ L L H I+
Sbjct: 447 YRNFRTFTSPRPTQFSCVAVDASGEIVSAGAQDSFEIFVWSMQTGRLLDVLSGHEGPISG 506
Query: 370 LCFSPNRYWLC-AAFGPSIKIWDL 302
LCF+P + L A++ ++++WD+
Sbjct: 507 LCFNPMKSVLASASWDKTVRLWDM 530
Score = 39.9 bits (89), Expect = 0.009
Identities = 40/163 (24%), Positives = 65/163 (39%), Gaps = 13/163 (7%)
Frame = -2
Query: 592 IVSCGWDRTVK--VWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLN 419
IVS G + + VW + +L GH G ++ + +P S+ AS D LWD+
Sbjct: 472 IVSAGAQDSFEIFVWSMQTGRLLDVLSGHEGPISGLCFNPMKSVLASASWDKTVRLWDMF 531
Query: 418 DG-KHLHTLDHNDIITALCFSPNRYWLC-AAFGPSIKIWD---------LESKEMVEELR 272
D + TL A+ F P+ L A I WD +E + ++ R
Sbjct: 532 DSWRTKETLALTSDALAVTFRPDGAELAVATLNSQITFWDPENAVQTGSIEGRHDLKTGR 591
Query: 271 PEIINQTQTSKTDPPQCLSLAWSTDGQTLFAGYSDNTIRVWQV 143
E+ T +L +S DG ++ AG + ++ V
Sbjct: 592 KELDKITAKHAAKGKAFTALCYSADGHSILAGGMSKFVCIYHV 634
Score = 37.5 bits (83), Expect = 0.048
Identities = 23/100 (23%), Positives = 43/100 (43%), Gaps = 2/100 (2%)
Frame = -2
Query: 595 IIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGSLCASGGKDMKAMLWDLND 416
I C + VW + + GH + + SPDG +GG D K +W+
Sbjct: 345 IAFGCSGLGQLLVWEWQSESYVLKQQGHFNSMVALAYSPDGQYIVTGGDDGKVKVWNTLS 404
Query: 415 GKHLHTL-DHNDIITALCFSPNRY-WLCAAFGPSIKIWDL 302
G T +H+ +T + F+ Y + ++ +++ +DL
Sbjct: 405 GFCFVTFTEHSSGVTGVTFTATGYVVVTSSMDGTVRAFDL 444
Score = 36.7 bits (81), Expect = 0.084
Identities = 20/75 (26%), Positives = 35/75 (46%)
Frame = -2
Query: 649 GHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLGHSGYLNTVTVSPDGS 470
GH +S + F+P + ++ S WD+TV++W + + L + VT PDG+
Sbjct: 499 GHEGPISGLCFNPMKS--VLASASWDKTVRLWDMFDSWRTKETLALTSDALAVTFRPDGA 556
Query: 469 LCASGGKDMKAMLWD 425
A + + WD
Sbjct: 557 ELAVATLNSQITFWD 571
Score = 36.3 bits (80), Expect = 0.11
Identities = 24/99 (24%), Positives = 45/99 (45%)
Frame = -2
Query: 694 LWNTLAECKYTIQDDGHSDWVSCVRFSPNHANPIIVSCGWDRTVKVWHLTNCKLKINHLG 515
+W +E Y ++ GH + + + +SP+ IV+ G D VKVW+ + +
Sbjct: 357 VWEWQSE-SYVLKQQGHFNSMVALAYSPD--GQYIVTGGDDGKVKVWNTLSGFCFVTFTE 413
Query: 514 HSGYLNTVTVSPDGSLCASGGKDMKAMLWDLNDGKHLHT 398
HS + VT + G + + D +DL+ ++ T
Sbjct: 414 HSSGVTGVTFTATGYVVVTSSMDGTVRAFDLHRYRNFRT 452
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 118,334,925
Number of Sequences: 237096
Number of extensions: 2750776
Number of successful extensions: 15115
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 10457
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 13389
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8455186714
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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