Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P14_pT_A22
(779 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X14968-1|CAA33094.1| 404|Homo sapiens protein ( Human testis mR... 222 1e-57
BC075800-1|AAH75800.1| 418|Homo sapiens protein kinase, cAMP-de... 218 2e-56
M31158-1|AAA60099.1| 418|Homo sapiens cAMP-dependent protein ki... 217 5e-56
BT007225-1|AAP35889.1| 382|Homo sapiens protein kinase, cAMP-de... 192 9e-49
BC002763-1|AAH02763.1| 382|Homo sapiens PRKAR2A protein protein. 192 9e-49
BC036828-1|AAH36828.2| 381|Homo sapiens protein kinase, cAMP-de... 180 7e-45
BC026734-1|AAH26734.1| 381|Homo sapiens PRKAR1B protein protein. 180 7e-45
M65066-1|AAC37564.1| 380|Homo sapiens cAMP-dependent protein ki... 177 3e-44
M33336-1|AAB50921.1| 381|Homo sapiens cAMP-dependent protein ki... 172 1e-42
M18468-1|AAB50922.1| 381|Homo sapiens cAMP-dependent protein ki... 172 1e-42
BC093042-1|AAH93042.1| 381|Homo sapiens protein kinase, cAMP-de... 172 1e-42
BC036285-1|AAH36285.1| 381|Homo sapiens protein kinase, cAMP-de... 172 1e-42
AC004492-1|AAC08318.1| 112|Homo sapiens CAMP-DEPENDENT PROTEIN ... 120 6e-27
Z92868-1|CAB07437.1| 686|Homo sapiens cGMP-dependent protein ki... 103 5e-22
Z92867-1|CAB07436.1| 671|Homo sapiens cGMP-dependent protein ki... 103 5e-22
Y07512-1|CAA68810.1| 686|Homo sapiens protein ( Human mRNA for ... 103 5e-22
EF560730-1|ABQ59040.1| 686|Homo sapiens PRKG1 protein protein. 103 5e-22
D45864-1|BAA08297.1| 671|Homo sapiens cGMP-dependent protein ki... 103 5e-22
BC127090-1|AAI27091.1| 686|Homo sapiens protein kinase, cGMP-de... 103 5e-22
AL928686-2|CAI40743.1| 686|Homo sapiens protein kinase, cGMP-de... 103 5e-22
AL928686-1|CAI40742.1| 659|Homo sapiens protein kinase, cGMP-de... 103 5e-22
AL731537-3|CAI17115.1| 686|Homo sapiens protein kinase, cGMP-de... 103 5e-22
AL731537-2|CAI17114.1| 659|Homo sapiens protein kinase, cGMP-de... 103 5e-22
AL391378-2|CAI39626.1| 686|Homo sapiens protein kinase, cGMP-de... 103 5e-22
AL391378-1|CAI39625.1| 659|Homo sapiens protein kinase, cGMP-de... 103 5e-22
AL157399-2|CAI41305.1| 686|Homo sapiens protein kinase, cGMP-de... 103 5e-22
AL157399-1|CAI41304.1| 659|Homo sapiens protein kinase, cGMP-de... 103 5e-22
AC006387-1|AAS07389.1| 306|Homo sapiens unknown protein. 101 2e-21
Y16106-1|CAA76073.1| 734|Homo sapiens cGMP-dependant protein ki... 94 4e-19
X94612-1|CAA64318.1| 762|Homo sapiens Type II cGMP-dependent pr... 94 4e-19
D70899-1|BAA18934.1| 762|Homo sapiens cGMP-dependent protein ki... 94 4e-19
BC062688-1|AAH62688.1| 312|Homo sapiens PRKG1 protein protein. 90 9e-18
AL391378-3|CAI39627.1| 181|Homo sapiens protein kinase, cGMP-de... 90 9e-18
AL157399-3|CAI41306.1| 181|Homo sapiens protein kinase, cGMP-de... 90 9e-18
L03357-1|AAA60266.1| 593|Homo sapiens RET tyrosine kinase/cAMP ... 69 1e-11
BC070478-1|AAH70478.1| 80|Homo sapiens PRKAR1B protein protein. 58 3e-08
BC051768-1|AAH51768.1| 1327|Homo sapiens patatin-like phospholip... 54 6e-07
BC050553-1|AAH50553.1| 1327|Homo sapiens patatin-like phospholip... 54 6e-07
AJ238850-1|CAB52754.1| 1203|Homo sapiens hyperpolarization-activ... 54 6e-07
AJ132429-1|CAB42604.1| 1203|Homo sapiens hyperpolarization-activ... 54 6e-07
AJ004832-1|CAA06164.1| 1327|Homo sapiens neuropathy target ester... 54 6e-07
AJ133727-1|CAB42630.1| 889|Homo sapiens hyperpolarization-activ... 53 1e-06
AJ012582-1|CAB42602.1| 889|Homo sapiens hyperpolarization-activ... 53 1e-06
AF065164-1|AAC28444.2| 889|Homo sapiens hyperpolarization-activ... 53 1e-06
AF064877-1|AAC39760.1| 597|Homo sapiens ion channel BCNG-2 prot... 53 1e-06
BC038229-1|AAH38229.1| 1332|Homo sapiens PNPLA6 protein protein. 52 2e-06
AL365502-7|CAI14582.1| 1317|Homo sapiens patatin-like phospholip... 52 3e-06
AL365502-6|CAI14581.1| 1281|Homo sapiens patatin-like phospholip... 52 3e-06
AL365502-5|CAI14579.1| 923|Homo sapiens patatin-like phospholip... 52 3e-06
AK125060-1|BAC86036.1| 1317|Homo sapiens protein ( Homo sapiens ... 52 3e-06
BC028024-1|AAH28024.2| 450|Homo sapiens HCN3 protein protein. 49 2e-05
BC000066-1|AAH00066.1| 571|Homo sapiens Unknown (protein for IM... 49 2e-05
AL713999-31|CAI95100.1| 774|Homo sapiens hyperpolarization acti... 49 2e-05
AF488550-1|AAO49470.1| 774|Homo sapiens hyperpolarization activ... 49 2e-05
AB040968-1|BAA96059.2| 711|Homo sapiens KIAA1535 protein protein. 49 2e-05
AF064876-1|AAC39759.1| 749|Homo sapiens ion channel BCNG-1 prot... 48 4e-05
U78516-1|AAD03422.1| 1011|Homo sapiens cAMP-regulated guanine nu... 47 7e-05
BC040183-1|AAH40183.1| 867|Homo sapiens RAPGEF4 protein protein. 47 7e-05
BC024004-1|AAH24004.1| 1011|Homo sapiens Rap guanine nucleotide ... 47 7e-05
AB027471-1|BAB72179.1| 1011|Homo sapiens cAMP-GEFII protein. 47 7e-05
AF488549-1|AAO49469.1| 890|Homo sapiens hyperpolarization activ... 45 3e-04
U78169-1|AAD02890.1| 556|Homo sapiens cAMP-regulated guanine nu... 44 8e-04
U78168-1|AAD12740.1| 881|Homo sapiens cAMP-regulated guanine nu... 44 8e-04
BC092404-1|AAH92404.1| 881|Homo sapiens Rap guanine nucleotide ... 44 8e-04
BC068477-1|AAH68477.1| 343|Homo sapiens RAPGEF3 protein protein. 44 8e-04
BC040534-1|AAH40534.1| 321|Homo sapiens RAPGEF3 protein protein. 44 8e-04
BC017728-1|AAH17728.1| 881|Homo sapiens Rap guanine nucleotide ... 44 8e-04
AF103905-1|AAC83381.1| 881|Homo sapiens Rap1 guanine-nucleotide... 44 8e-04
BC040277-1|AAH40277.1| 474|Homo sapiens CNGA4 protein protein. 43 0.001
S76069-1|AAD14208.1| 261|Homo sapiens CNG3 protein. 43 0.001
BC096300-1|AAH96300.1| 694|Homo sapiens cyclic nucleotide gated... 43 0.001
BC096299-1|AAH96299.1| 676|Homo sapiens cyclic nucleotide gated... 43 0.001
BC096298-1|AAH96298.1| 694|Homo sapiens cyclic nucleotide gated... 43 0.001
AK131300-1|BAD18468.1| 698|Homo sapiens mRNA. protein. 43 0.001
AF065314-1|AAC17440.1| 694|Homo sapiens cone photoreceptor cGMP... 43 0.001
AC092675-2|AAY24181.1| 694|Homo sapiens unknown protein. 43 0.001
AB209681-1|BAD92918.1| 643|Homo sapiens RAP guanine-nucleotide-... 41 0.006
S76062-1|AAD14206.1| 261|Homo sapiens CNG1 protein. 38 0.054
S42457-1|AAB22778.1| 686|Homo sapiens rod photoreceptor cGMP-ga... 38 0.054
AC107068-3|AAY40919.1| 690|Homo sapiens unknown protein. 38 0.054
AK055880-1|BAB71033.1| 702|Homo sapiens protein ( Homo sapiens ... 37 0.094
AB033108-1|BAA86596.1| 1117|Homo sapiens KIAA1282 protein protein. 37 0.094
AB022696-1|BAA83590.1| 1083|Homo sapiens BEC1 protein. 37 0.094
AF032897-1|AAD01946.1| 1196|Homo sapiens potassium channel subun... 36 0.12
S76067-1|AAD14207.1| 261|Homo sapiens CNG2 protein. 36 0.16
BC126304-1|AAI26305.1| 664|Homo sapiens cyclic nucleotide gated... 36 0.16
BC126302-1|AAI26303.1| 664|Homo sapiens cyclic nucleotide gated... 36 0.16
BC073979-1|AAH73979.1| 988|Homo sapiens potassium voltage-gated... 34 0.50
AF472412-1|AAM49565.1| 988|Homo sapiens potassium channel HEAG2... 34 0.50
AF418206-1|AAM28435.1| 988|Homo sapiens voltage-gated potassium... 34 0.50
AC007740-1|AAX93153.1| 940|Homo sapiens unknown protein. 34 0.50
M84741-1|AAA52010.1| 690|Homo sapiens cGMP-gated cation channel... 34 0.66
BC113709-1|AAI13710.1| 962|Homo sapiens potassium voltage-gated... 34 0.66
AL590132-2|CAH71752.1| 962|Homo sapiens potassium voltage-gated... 34 0.66
AL590132-1|CAH71753.1| 989|Homo sapiens potassium voltage-gated... 34 0.66
AK091877-1|BAC03764.1| 905|Homo sapiens protein ( Homo sapiens ... 34 0.66
AK090969-1|BAC03559.1| 430|Homo sapiens protein ( Homo sapiens ... 34 0.66
AJ001366-1|CAA04700.1| 962|Homo sapiens protein ( Homo sapiens ... 34 0.66
AF311913-1|AAG40871.1| 994|Homo sapiens Eag-related gene member... 34 0.66
AF078742-1|AAC68669.1| 989|Homo sapiens voltage-gated potassium... 34 0.66
AF078741-1|AAC68668.1| 962|Homo sapiens voltage-gated potassium... 34 0.66
AY053503-1|AAL15429.1| 1107|Homo sapiens ether-a-go-go-like pota... 31 3.5
AB209053-1|BAD92290.1| 583|Homo sapiens potassium voltage-gated... 31 3.5
U04270-1|AAA62473.1| 1159|Homo sapiens putative potassium channe... 31 6.1
DQ784808-1|ABQ01243.1| 1159|Homo sapiens potassium voltage-gated... 31 6.1
DQ525913-1|ABF71886.1| 1159|Homo sapiens voltage-gated potassium... 31 6.1
BC004311-1|AAH04311.2| 444|Homo sapiens KCNH2 protein protein. 31 6.1
AJ512214-1|CAD54447.1| 819|Homo sapiens potassium channel 1b pr... 31 6.1
AJ010538-1|CAA09232.1| 1133|Homo sapiens ether-a-go-go-related p... 31 6.1
AF363636-1|AAL37559.1| 1159|Homo sapiens ether-a-go-go-related K... 31 6.1
AB009071-1|BAA37096.1| 1159|Homo sapiens HERG protein. 31 6.1
>X14968-1|CAA33094.1| 404|Homo sapiens protein ( Human testis mRNA
for the RII-alpha subunit of cAMP dependent protein
kinase. ).
Length = 404
Score = 222 bits (542), Expect = 1e-57
Identities = 113/213 (53%), Positives = 144/213 (67%), Gaps = 7/213 (3%)
Frame = -1
Query: 776 VTGDDRVEKVVHTYEGSGSFGEXAXMYNMPRAAXVRAQTAGALWAMDRHTFRRILLKSAF 597
VT D++ V Y+ GSFGE A MYN PRAA + A + G+LW +DR TFRRI++K+
Sbjct: 188 VTKDNQTRSVGQ-YDNRGSFGELALMYNTPRAATIVATSEGSLWGLDRVTFRRIIVKNNA 246
Query: 596 KKRKLYEELLDKVPMLKALQPYERANLADALLPRTLVEGELIIRQGDTADGMYFVEDGSV 417
KKRK++E ++ VP+LK+L+ ER + D + + +GE II QG+ AD Y +E G V
Sbjct: 247 KKRKMFESFIESVPLLKSLEVSERMKIVDVIGEKIYKDGERIITQGEKADSFYIIESGEV 306
Query: 416 SIRI------TRDDGN-EHEIKRLGKGDYFGELALVTHKPRAASVYAIGATKVAFLDVET 258
SI I +D GN E EI R KG YFGELALVT+KPRAAS YA+G K +DV+
Sbjct: 307 SILIRSRTKSNKDGGNQEVEIARCHKGQYFGELALVTNKPRAASAYAVGDVKCLVMDVQA 366
Query: 257 FERLLGPCMEIMKRNIDXYEEQLVKLFGDKSNL 159
FERLLGPCM+IMKRNI YEEQLVK+FG +L
Sbjct: 367 FERLLGPCMDIMKRNISHYEEQLVKMFGSSVDL 399
Score = 63.3 bits (147), Expect = 9e-10
Identities = 37/132 (28%), Positives = 65/132 (49%)
Frame = -1
Query: 638 DRHTFRRILLKSAFKKRKLYEELLDKVPMLKALQPYERANLADALLPRTLVEGELIIRQG 459
+ T R++ ++R +E + + K L + + + DA+ R + E +I QG
Sbjct: 111 EEDTDPRVIHPKTDEQRCRLQEACKDILLFKNLDQEQLSQVLDAMFERIVKADEHVIDQG 170
Query: 458 DTADGMYFVEDGSVSIRITRDDGNEHEIKRLGKGDYFGELALVTHKPRAASVYAIGATKV 279
D D Y +E G+ I +T+D+ + + FGELAL+ + PRAA++ A +
Sbjct: 171 DDGDNFYVIERGTYDILVTKDN-QTRSVGQYDNRGSFGELALMYNTPRAATIVATSEGSL 229
Query: 278 AFLDVETFERLL 243
LD TF R++
Sbjct: 230 WGLDRVTFRRII 241
>BC075800-1|AAH75800.1| 418|Homo sapiens protein kinase,
cAMP-dependent, regulatory, type II, beta protein.
Length = 418
Score = 218 bits (532), Expect = 2e-56
Identities = 108/210 (51%), Positives = 139/210 (66%), Gaps = 6/210 (2%)
Frame = -1
Query: 764 DRVEKVVHTYEGSGSFGEXAXMYNMPRAAXVRAQTAGALWAMDRHTFRRILLKSAFKKRK 585
D V + V Y+ GSFGE A MYN PRAA + A + GALW +DR TFRRI++K+ KKRK
Sbjct: 206 DGVGRCVGNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFRRIIVKNNAKKRK 265
Query: 584 LYEELLDKVPMLKALQPYERANLADALLPRTLVEGELIIRQGDTADGMYFVEDGSVSIRI 405
+YE ++ +P LK+L+ ER + D + + +GE II QGD+AD + VE G V I +
Sbjct: 266 MYESFIESLPFLKSLEFSERLKVVDVIGTKVYNDGEQIIAQGDSADSFFIVESGEVKITM 325
Query: 404 TR------DDGNEHEIKRLGKGDYFGELALVTHKPRAASVYAIGATKVAFLDVETFERLL 243
R ++ EI R +G YFGELALVT+KPRAAS +AIG K +DV+ FERLL
Sbjct: 326 KRKGKSEVEENGAVEIARCSRGQYFGELALVTNKPRAASAHAIGTVKCLAMDVQAFERLL 385
Query: 242 GPCMEIMKRNIDXYEEQLVKLFGDKSNLTD 153
GPCMEIMKRNI YEEQLV LFG ++ +
Sbjct: 386 GPCMEIMKRNIATYEEQLVALFGTNMDIVE 415
Score = 63.3 bits (147), Expect = 9e-10
Identities = 37/126 (29%), Positives = 63/126 (50%)
Frame = -1
Query: 620 RILLKSAFKKRKLYEELLDKVPMLKALQPYERANLADALLPRTLVEGELIIRQGDTADGM 441
RI+ +R +E + + K L P + + + DA+ + + +GE +I QGD D
Sbjct: 132 RIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKDGEHVIDQGDDGDNF 191
Query: 440 YFVEDGSVSIRITRDDGNEHEIKRLGKGDYFGELALVTHKPRAASVYAIGATKVAFLDVE 261
Y ++ G+ I + + DG + FGELAL+ + PRAA++ A + LD
Sbjct: 192 YVIDRGTFDIYV-KCDGVGRCVGNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRV 250
Query: 260 TFERLL 243
TF R++
Sbjct: 251 TFRRII 256
>M31158-1|AAA60099.1| 418|Homo sapiens cAMP-dependent protein
kinase subunit RII-beta protein.
Length = 418
Score = 217 bits (529), Expect = 5e-56
Identities = 107/210 (50%), Positives = 139/210 (66%), Gaps = 6/210 (2%)
Frame = -1
Query: 764 DRVEKVVHTYEGSGSFGEXAXMYNMPRAAXVRAQTAGALWAMDRHTFRRILLKSAFKKRK 585
D V + V Y+ GSFGE A MYN PRAA + A + GALW +DR TFRRI++K+ KKRK
Sbjct: 206 DGVGRCVGNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFRRIIVKNNAKKRK 265
Query: 584 LYEELLDKVPMLKALQPYERANLADALLPRTLVEGELIIRQGDTADGMYFVEDGSVSIRI 405
+YE ++ +P LK+L+ ER + D + + +GE II QGD+AD + VE G V I +
Sbjct: 266 MYESFIESLPFLKSLEFSERLKVVDVIGTKVYNDGEQIIAQGDSADSFFIVESGEVKITM 325
Query: 404 TR------DDGNEHEIKRLGKGDYFGELALVTHKPRAASVYAIGATKVAFLDVETFERLL 243
R ++ E+ R +G YFGELALVT+KPRAAS +AIG K +DV+ FERLL
Sbjct: 326 KRKGKSEVEENGAVEMPRCSRGQYFGELALVTNKPRAASAHAIGTVKCLAMDVQAFERLL 385
Query: 242 GPCMEIMKRNIDXYEEQLVKLFGDKSNLTD 153
GPCMEIMKRNI YEEQLV LFG ++ +
Sbjct: 386 GPCMEIMKRNIATYEEQLVALFGTNMDIVE 415
Score = 63.3 bits (147), Expect = 9e-10
Identities = 37/126 (29%), Positives = 63/126 (50%)
Frame = -1
Query: 620 RILLKSAFKKRKLYEELLDKVPMLKALQPYERANLADALLPRTLVEGELIIRQGDTADGM 441
RI+ +R +E + + K L P + + + DA+ + + +GE +I QGD D
Sbjct: 132 RIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKDGEHVIDQGDDGDNF 191
Query: 440 YFVEDGSVSIRITRDDGNEHEIKRLGKGDYFGELALVTHKPRAASVYAIGATKVAFLDVE 261
Y ++ G+ I + + DG + FGELAL+ + PRAA++ A + LD
Sbjct: 192 YVIDRGTFDIYV-KCDGVGRCVGNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRV 250
Query: 260 TFERLL 243
TF R++
Sbjct: 251 TFRRII 256
>BT007225-1|AAP35889.1| 382|Homo sapiens protein kinase,
cAMP-dependent, regulatory, type II, alpha protein.
Length = 382
Score = 192 bits (469), Expect = 9e-49
Identities = 102/207 (49%), Positives = 133/207 (64%), Gaps = 1/207 (0%)
Frame = -1
Query: 776 VTGDDRVEKVVHTYEGSGSFGEXAXMYNMPRAAXVRAQTAGALWAMDRHTFRRILLKSAF 597
VT D++ V Y+ GSFGE A MYN PRAA + A + G+LW +DR TFRRI++K+
Sbjct: 188 VTKDNQTRSVGQ-YDNRGSFGELALMYNTPRAATIVATSEGSLWGLDRVTFRRIIVKNNA 246
Query: 596 KKRKLYEELLDKVPMLKALQPYERANLADALLPRTLVEGELIIRQGDTADGMYFVEDGSV 417
KKRK++E ++ VP+LK+L+ ER + D + + +GE II Q
Sbjct: 247 KKRKMFESFIESVPLLKSLEVSERMKIVDVIGEKIYKDGERIITQ--------------- 291
Query: 416 SIRITRDDGNEH-EIKRLGKGDYFGELALVTHKPRAASVYAIGATKVAFLDVETFERLLG 240
+ +D GN+ EI R KG YFGELALVT+KPRAAS YA+G K +DV+ FERLLG
Sbjct: 292 -TKSNKDGGNQEVEIARCHKGQYFGELALVTNKPRAASAYAVGDVKCLVMDVQAFERLLG 350
Query: 239 PCMEIMKRNIDXYEEQLVKLFGDKSNL 159
PCM+IMKRNI YEEQLVK+FG +L
Sbjct: 351 PCMDIMKRNISHYEEQLVKMFGSSVDL 377
Score = 63.3 bits (147), Expect = 9e-10
Identities = 37/132 (28%), Positives = 65/132 (49%)
Frame = -1
Query: 638 DRHTFRRILLKSAFKKRKLYEELLDKVPMLKALQPYERANLADALLPRTLVEGELIIRQG 459
+ T R++ ++R +E + + K L + + + DA+ R + E +I QG
Sbjct: 111 EEDTDPRVIHPKTDEQRCRLQEACKDILLFKNLDQEQLSQVLDAMFERIVKADEHVIDQG 170
Query: 458 DTADGMYFVEDGSVSIRITRDDGNEHEIKRLGKGDYFGELALVTHKPRAASVYAIGATKV 279
D D Y +E G+ I +T+D+ + + FGELAL+ + PRAA++ A +
Sbjct: 171 DDGDNFYVIERGTYDILVTKDN-QTRSVGQYDNRGSFGELALMYNTPRAATIVATSEGSL 229
Query: 278 AFLDVETFERLL 243
LD TF R++
Sbjct: 230 WGLDRVTFRRII 241
>BC002763-1|AAH02763.1| 382|Homo sapiens PRKAR2A protein protein.
Length = 382
Score = 192 bits (469), Expect = 9e-49
Identities = 102/207 (49%), Positives = 133/207 (64%), Gaps = 1/207 (0%)
Frame = -1
Query: 776 VTGDDRVEKVVHTYEGSGSFGEXAXMYNMPRAAXVRAQTAGALWAMDRHTFRRILLKSAF 597
VT D++ V Y+ GSFGE A MYN PRAA + A + G+LW +DR TFRRI++K+
Sbjct: 188 VTKDNQTRSVGQ-YDNRGSFGELALMYNTPRAATIVATSEGSLWGLDRVTFRRIIVKNNA 246
Query: 596 KKRKLYEELLDKVPMLKALQPYERANLADALLPRTLVEGELIIRQGDTADGMYFVEDGSV 417
KKRK++E ++ VP+LK+L+ ER + D + + +GE II Q
Sbjct: 247 KKRKMFESFIESVPLLKSLEVSERMKIVDVIGEKIYKDGERIITQ--------------- 291
Query: 416 SIRITRDDGNEH-EIKRLGKGDYFGELALVTHKPRAASVYAIGATKVAFLDVETFERLLG 240
+ +D GN+ EI R KG YFGELALVT+KPRAAS YA+G K +DV+ FERLLG
Sbjct: 292 -TKSNKDGGNQEVEIARCHKGQYFGELALVTNKPRAASAYAVGDVKCLVMDVQAFERLLG 350
Query: 239 PCMEIMKRNIDXYEEQLVKLFGDKSNL 159
PCM+IMKRNI YEEQLVK+FG +L
Sbjct: 351 PCMDIMKRNISHYEEQLVKMFGSSVDL 377
Score = 63.3 bits (147), Expect = 9e-10
Identities = 37/132 (28%), Positives = 65/132 (49%)
Frame = -1
Query: 638 DRHTFRRILLKSAFKKRKLYEELLDKVPMLKALQPYERANLADALLPRTLVEGELIIRQG 459
+ T R++ ++R +E + + K L + + + DA+ R + E +I QG
Sbjct: 111 EEDTDPRVIHPKTDEQRCRLQEACKDILLFKNLDQEQLSQVLDAMFERIVKADEHVIDQG 170
Query: 458 DTADGMYFVEDGSVSIRITRDDGNEHEIKRLGKGDYFGELALVTHKPRAASVYAIGATKV 279
D D Y +E G+ I +T+D+ + + FGELAL+ + PRAA++ A +
Sbjct: 171 DDGDNFYVIERGTYDILVTKDN-QTRSVGQYDNRGSFGELALMYNTPRAATIVATSEGSL 229
Query: 278 AFLDVETFERLL 243
LD TF R++
Sbjct: 230 WGLDRVTFRRII 241
>BC036828-1|AAH36828.2| 381|Homo sapiens protein kinase,
cAMP-dependent, regulatory, type I, beta protein.
Length = 381
Score = 180 bits (437), Expect = 7e-45
Identities = 91/186 (48%), Positives = 123/186 (66%), Gaps = 1/186 (0%)
Frame = -1
Query: 755 EKVVHTYEGSGSFGEXAXMYNMPRAAXVRAQTAGALWAMDRHTFRRILLKSAFKKRKLYE 576
E V + EG GSFGE A +Y PRAA V+A+T LW +DR ++RRIL+ S +KRK+YE
Sbjct: 189 EWVTNISEG-GSFGELALIYGTPRAATVKAKTDLKLWGIDRDSYRRILMGSTLRKRKMYE 247
Query: 575 ELLDKVPMLKALQPYERANLADALLPRTLVEGELIIRQGDTADGMYFVEDGSVSIRITRD 396
E L KV +L++L+ +ER +ADAL P +GE I+ QG+ D Y + +G+ S+ R
Sbjct: 248 EFLSKVSILESLEKWERLTVADALEPVQFEDGEKIVVQGEPGDDFYIITEGTASVLQRRS 307
Query: 395 DGNEH-EIKRLGKGDYFGELALVTHKPRAASVYAIGATKVAFLDVETFERLLGPCMEIMK 219
E+ E+ RLG DYFGE+AL+ ++PRAA+V A G K LD FER+LGPC EI+K
Sbjct: 308 PNEEYVEVGRLGPSDYFGEIALLLNRPRAATVVARGPLKCVKLDRPRFERVLGPCSEILK 367
Query: 218 RNIDXY 201
RNI Y
Sbjct: 368 RNIQRY 373
Score = 70.5 bits (165), Expect = 6e-12
Identities = 46/153 (30%), Positives = 77/153 (50%)
Frame = -1
Query: 638 DRHTFRRILLKSAFKKRKLYEELLDKVPMLKALQPYERANLADALLPRTLVEGELIIRQG 459
D ++ R ++ +K + + K + L ER+++ DA+ P T + GE +I+QG
Sbjct: 109 DAVSYVRKVIPKDYKTMTALAKAISKNVLFAHLDDNERSDIFDAMFPVTHIAGETVIQQG 168
Query: 458 DTADGMYFVEDGSVSIRITRDDGNEHEIKRLGKGDYFGELALVTHKPRAASVYAIGATKV 279
+ D Y V+ G V + + N + + +G FGELAL+ PRAA+V A K+
Sbjct: 169 NEGDNFYVVDQGEVDVYV-----NGEWVTNISEGGSFGELALIYGTPRAATVKAKTDLKL 223
Query: 278 AFLDVETFERLLGPCMEIMKRNIDXYEEQLVKL 180
+D +++ R+L M R YEE L K+
Sbjct: 224 WGIDRDSYRRIL---MGSTLRKRKMYEEFLSKV 253
>BC026734-1|AAH26734.1| 381|Homo sapiens PRKAR1B protein protein.
Length = 381
Score = 180 bits (437), Expect = 7e-45
Identities = 91/186 (48%), Positives = 123/186 (66%), Gaps = 1/186 (0%)
Frame = -1
Query: 755 EKVVHTYEGSGSFGEXAXMYNMPRAAXVRAQTAGALWAMDRHTFRRILLKSAFKKRKLYE 576
E V + EG GSFGE A +Y PRAA V+A+T LW +DR ++RRIL+ S +KRK+YE
Sbjct: 189 EWVTNISEG-GSFGELALIYGTPRAATVKAKTDLKLWGIDRDSYRRILMGSTLRKRKMYE 247
Query: 575 ELLDKVPMLKALQPYERANLADALLPRTLVEGELIIRQGDTADGMYFVEDGSVSIRITRD 396
E L KV +L++L+ +ER +ADAL P +GE I+ QG+ D Y + +G+ S+ R
Sbjct: 248 EFLSKVSILESLEKWERLTVADALEPVQFEDGEKIVVQGEPGDDFYIITEGTASVLQRRS 307
Query: 395 DGNEH-EIKRLGKGDYFGELALVTHKPRAASVYAIGATKVAFLDVETFERLLGPCMEIMK 219
E+ E+ RLG DYFGE+AL+ ++PRAA+V A G K LD FER+LGPC EI+K
Sbjct: 308 PNEEYVEVGRLGPSDYFGEIALLLNRPRAATVVARGPLKCVKLDRPRFERVLGPCSEILK 367
Query: 218 RNIDXY 201
RNI Y
Sbjct: 368 RNIQRY 373
Score = 70.5 bits (165), Expect = 6e-12
Identities = 46/153 (30%), Positives = 77/153 (50%)
Frame = -1
Query: 638 DRHTFRRILLKSAFKKRKLYEELLDKVPMLKALQPYERANLADALLPRTLVEGELIIRQG 459
D ++ R ++ +K + + K + L ER+++ DA+ P T + GE +I+QG
Sbjct: 109 DAVSYVRKVIPKDYKTMTALAKAISKNVLFAHLDDNERSDIFDAMFPVTHIAGETVIQQG 168
Query: 458 DTADGMYFVEDGSVSIRITRDDGNEHEIKRLGKGDYFGELALVTHKPRAASVYAIGATKV 279
+ D Y V+ G V + + N + + +G FGELAL+ PRAA+V A K+
Sbjct: 169 NEGDNFYVVDQGEVDVYV-----NGEWVTNISEGGSFGELALIYGTPRAATVKAKTDLKL 223
Query: 278 AFLDVETFERLLGPCMEIMKRNIDXYEEQLVKL 180
+D +++ R+L M R YEE L K+
Sbjct: 224 WGIDRDSYRRIL---MGSTLRKRKMYEEFLSKV 253
>M65066-1|AAC37564.1| 380|Homo sapiens cAMP-dependent protein
kinase RI-beta regulatory subunit protein.
Length = 380
Score = 177 bits (432), Expect = 3e-44
Identities = 90/186 (48%), Positives = 122/186 (65%), Gaps = 1/186 (0%)
Frame = -1
Query: 755 EKVVHTYEGSGSFGEXAXMYNMPRAAXVRAQTAGALWAMDRHTFRRILLKSAFKKRKLYE 576
E V + EG GSFGE A +Y PRAA V+A+T LW +DR ++RRIL+ S +KRK+YE
Sbjct: 188 EWVTNISEG-GSFGELALIYGTPRAATVKAKTDLKLWGIDRDSYRRILMGSTLRKRKMYE 246
Query: 575 ELLDKVPMLKALQPYERANLADALLPRTLVEGELIIRQGDTADGMYFVEDGSVSIRITRD 396
E L KV +L++L+ +ER +AD L P +GE I+ QG+ D Y + +G+ S+ R
Sbjct: 247 EFLSKVSILESLEKWERLTVADRLEPVQFEDGEKIVVQGEPGDDFYIITEGTASVLQRRS 306
Query: 395 DGNEH-EIKRLGKGDYFGELALVTHKPRAASVYAIGATKVAFLDVETFERLLGPCMEIMK 219
E+ E+ RLG DYFGE+AL+ ++PRAA+V A G K LD FER+LGPC EI+K
Sbjct: 307 PNEEYVEVGRLGPSDYFGEIALLLNRPRAATVVARGPLKCVKLDRPRFERVLGPCSEILK 366
Query: 218 RNIDXY 201
RNI Y
Sbjct: 367 RNIQRY 372
Score = 70.5 bits (165), Expect = 6e-12
Identities = 46/153 (30%), Positives = 77/153 (50%)
Frame = -1
Query: 638 DRHTFRRILLKSAFKKRKLYEELLDKVPMLKALQPYERANLADALLPRTLVEGELIIRQG 459
D ++ R ++ +K + + K + L ER+++ DA+ P T + GE +I+QG
Sbjct: 108 DAVSYVRKVIPKDYKTMTALAKAISKNVLFAHLDDNERSDIFDAMFPVTHIAGETVIQQG 167
Query: 458 DTADGMYFVEDGSVSIRITRDDGNEHEIKRLGKGDYFGELALVTHKPRAASVYAIGATKV 279
+ D Y V+ G V + + N + + +G FGELAL+ PRAA+V A K+
Sbjct: 168 NEGDNFYVVDQGEVDVYV-----NGEWVTNISEGGSFGELALIYGTPRAATVKAKTDLKL 222
Query: 278 AFLDVETFERLLGPCMEIMKRNIDXYEEQLVKL 180
+D +++ R+L M R YEE L K+
Sbjct: 223 WGIDRDSYRRIL---MGSTLRKRKMYEEFLSKV 252
>M33336-1|AAB50921.1| 381|Homo sapiens cAMP-dependent protein
kinase type I-alpha subunit protein.
Length = 381
Score = 172 bits (419), Expect = 1e-42
Identities = 84/176 (47%), Positives = 117/176 (66%), Gaps = 1/176 (0%)
Frame = -1
Query: 725 GSFGEXAXMYNMPRAAXVRAQTAGALWAMDRHTFRRILLKSAFKKRKLYEELLDKVPMLK 546
GSFGE A +Y PRAA V+A+T LW +DR ++RRIL+ S +KRK+YEE L KV +L+
Sbjct: 198 GSFGELALIYGTPRAATVKAKTNVKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSILE 257
Query: 545 ALQPYERANLADALLPRTLVEGELIIRQGDTADGMYFVEDGSVSIRITRDDGNEH-EIKR 369
+L +ER +ADAL P +G+ I+ QG+ D + + +GS ++ R + E E+ R
Sbjct: 258 SLDKWERLTVADALEPVQFEDGQKIVVQGEPGDEFFIILEGSAAVLQRRSENEEFVEVGR 317
Query: 368 LGKGDYFGELALVTHKPRAASVYAIGATKVAFLDVETFERLLGPCMEIMKRNIDXY 201
LG DYFGE+AL+ ++PRAA+V A G K LD FER+LGPC +I+KRNI Y
Sbjct: 318 LGPSDYFGEIALLMNRPRAATVVARGPLKCVKLDRPRFERVLGPCSDILKRNIQQY 373
Score = 69.7 bits (163), Expect = 1e-11
Identities = 44/153 (28%), Positives = 76/153 (49%)
Frame = -1
Query: 638 DRHTFRRILLKSAFKKRKLYEELLDKVPMLKALQPYERANLADALLPRTLVEGELIIRQG 459
D ++ R ++ +K + ++K + L ER+++ DA+ + + GE +I+QG
Sbjct: 109 DAASYVRKVIPKDYKTMAALAKAIEKNVLFSHLDDNERSDIFDAMFSVSFIAGETVIQQG 168
Query: 458 DTADGMYFVEDGSVSIRITRDDGNEHEIKRLGKGDYFGELALVTHKPRAASVYAIGATKV 279
D D Y ++ G + + N +G+G FGELAL+ PRAA+V A K+
Sbjct: 169 DEGDNFYVIDQGETDVYV-----NNEWATSVGEGGSFGELALIYGTPRAATVKAKTNVKL 223
Query: 278 AFLDVETFERLLGPCMEIMKRNIDXYEEQLVKL 180
+D +++ R+L M R YEE L K+
Sbjct: 224 WGIDRDSYRRIL---MGSTLRKRKMYEEFLSKV 253
Score = 31.1 bits (67), Expect = 4.7
Identities = 17/39 (43%), Positives = 21/39 (53%)
Frame = -1
Query: 728 SGSFGEXAXMYNMPRAAXVRAQTAGALWAMDRHTFRRIL 612
S FGE A + N PRAA V A+ +DR F R+L
Sbjct: 321 SDYFGEIALLMNRPRAATVVARGPLKCVKLDRPRFERVL 359
>M18468-1|AAB50922.1| 381|Homo sapiens cAMP-dependent protein
kinase regulatory subunit type 1 protein.
Length = 381
Score = 172 bits (419), Expect = 1e-42
Identities = 84/176 (47%), Positives = 117/176 (66%), Gaps = 1/176 (0%)
Frame = -1
Query: 725 GSFGEXAXMYNMPRAAXVRAQTAGALWAMDRHTFRRILLKSAFKKRKLYEELLDKVPMLK 546
GSFGE A +Y PRAA V+A+T LW +DR ++RRIL+ S +KRK+YEE L KV +L+
Sbjct: 198 GSFGELALIYGTPRAATVKAKTNVKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSILE 257
Query: 545 ALQPYERANLADALLPRTLVEGELIIRQGDTADGMYFVEDGSVSIRITRDDGNEH-EIKR 369
+L +ER +ADAL P +G+ I+ QG+ D + + +GS ++ R + E E+ R
Sbjct: 258 SLDKWERLTVADALEPVQFEDGQKIVVQGEPGDEFFIILEGSAAVLQRRSENEEFVEVGR 317
Query: 368 LGKGDYFGELALVTHKPRAASVYAIGATKVAFLDVETFERLLGPCMEIMKRNIDXY 201
LG DYFGE+AL+ ++PRAA+V A G K LD FER+LGPC +I+KRNI Y
Sbjct: 318 LGPSDYFGEIALLMNRPRAATVVARGPLKCVKLDRPRFERVLGPCSDILKRNIQQY 373
Score = 69.7 bits (163), Expect = 1e-11
Identities = 44/153 (28%), Positives = 76/153 (49%)
Frame = -1
Query: 638 DRHTFRRILLKSAFKKRKLYEELLDKVPMLKALQPYERANLADALLPRTLVEGELIIRQG 459
D ++ R ++ +K + ++K + L ER+++ DA+ + + GE +I+QG
Sbjct: 109 DAASYVRKVIPKDYKTMAALAKAIEKNVLFSHLDDNERSDIFDAMFSVSFIAGETVIQQG 168
Query: 458 DTADGMYFVEDGSVSIRITRDDGNEHEIKRLGKGDYFGELALVTHKPRAASVYAIGATKV 279
D D Y ++ G + + N +G+G FGELAL+ PRAA+V A K+
Sbjct: 169 DEGDNFYVIDQGETDVYV-----NNEWATSVGEGGSFGELALIYGTPRAATVKAKTNVKL 223
Query: 278 AFLDVETFERLLGPCMEIMKRNIDXYEEQLVKL 180
+D +++ R+L M R YEE L K+
Sbjct: 224 WGIDRDSYRRIL---MGSTLRKRKMYEEFLSKV 253
Score = 31.1 bits (67), Expect = 4.7
Identities = 17/39 (43%), Positives = 21/39 (53%)
Frame = -1
Query: 728 SGSFGEXAXMYNMPRAAXVRAQTAGALWAMDRHTFRRIL 612
S FGE A + N PRAA V A+ +DR F R+L
Sbjct: 321 SDYFGEIALLMNRPRAATVVARGPLKCVKLDRPRFERVL 359
>BC093042-1|AAH93042.1| 381|Homo sapiens protein kinase,
cAMP-dependent, regulatory, type I, alpha (tissue
specific exti protein.
Length = 381
Score = 172 bits (419), Expect = 1e-42
Identities = 84/176 (47%), Positives = 117/176 (66%), Gaps = 1/176 (0%)
Frame = -1
Query: 725 GSFGEXAXMYNMPRAAXVRAQTAGALWAMDRHTFRRILLKSAFKKRKLYEELLDKVPMLK 546
GSFGE A +Y PRAA V+A+T LW +DR ++RRIL+ S +KRK+YEE L KV +L+
Sbjct: 198 GSFGELALIYGTPRAATVKAKTNVKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSILE 257
Query: 545 ALQPYERANLADALLPRTLVEGELIIRQGDTADGMYFVEDGSVSIRITRDDGNEH-EIKR 369
+L +ER +ADAL P +G+ I+ QG+ D + + +GS ++ R + E E+ R
Sbjct: 258 SLDKWERLTVADALEPVQFEDGQKIVVQGEPGDEFFIILEGSAAVLQRRSENEEFVEVGR 317
Query: 368 LGKGDYFGELALVTHKPRAASVYAIGATKVAFLDVETFERLLGPCMEIMKRNIDXY 201
LG DYFGE+AL+ ++PRAA+V A G K LD FER+LGPC +I+KRNI Y
Sbjct: 318 LGPSDYFGEIALLMNRPRAATVVARGPLKCVKLDRPRFERVLGPCSDILKRNIQQY 373
Score = 69.7 bits (163), Expect = 1e-11
Identities = 44/153 (28%), Positives = 76/153 (49%)
Frame = -1
Query: 638 DRHTFRRILLKSAFKKRKLYEELLDKVPMLKALQPYERANLADALLPRTLVEGELIIRQG 459
D ++ R ++ +K + ++K + L ER+++ DA+ + + GE +I+QG
Sbjct: 109 DAASYVRKVIPKDYKTMAALAKAIEKNVLFSHLDDNERSDIFDAMFSVSFIAGETVIQQG 168
Query: 458 DTADGMYFVEDGSVSIRITRDDGNEHEIKRLGKGDYFGELALVTHKPRAASVYAIGATKV 279
D D Y ++ G + + N +G+G FGELAL+ PRAA+V A K+
Sbjct: 169 DEGDNFYVIDQGETDVYV-----NNEWATSVGEGGSFGELALIYGTPRAATVKAKTNVKL 223
Query: 278 AFLDVETFERLLGPCMEIMKRNIDXYEEQLVKL 180
+D +++ R+L M R YEE L K+
Sbjct: 224 WGIDRDSYRRIL---MGSTLRKRKMYEEFLSKV 253
Score = 31.1 bits (67), Expect = 4.7
Identities = 17/39 (43%), Positives = 21/39 (53%)
Frame = -1
Query: 728 SGSFGEXAXMYNMPRAAXVRAQTAGALWAMDRHTFRRIL 612
S FGE A + N PRAA V A+ +DR F R+L
Sbjct: 321 SDYFGEIALLMNRPRAATVVARGPLKCVKLDRPRFERVL 359
>BC036285-1|AAH36285.1| 381|Homo sapiens protein kinase,
cAMP-dependent, regulatory, type I, alpha (tissue
specific exti protein.
Length = 381
Score = 172 bits (419), Expect = 1e-42
Identities = 84/176 (47%), Positives = 117/176 (66%), Gaps = 1/176 (0%)
Frame = -1
Query: 725 GSFGEXAXMYNMPRAAXVRAQTAGALWAMDRHTFRRILLKSAFKKRKLYEELLDKVPMLK 546
GSFGE A +Y PRAA V+A+T LW +DR ++RRIL+ S +KRK+YEE L KV +L+
Sbjct: 198 GSFGELALIYGTPRAATVKAKTNVKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSILE 257
Query: 545 ALQPYERANLADALLPRTLVEGELIIRQGDTADGMYFVEDGSVSIRITRDDGNEH-EIKR 369
+L +ER +ADAL P +G+ I+ QG+ D + + +GS ++ R + E E+ R
Sbjct: 258 SLDKWERLTVADALEPVQFEDGQKIVVQGEPGDEFFIILEGSAAVLQRRSENEEFVEVGR 317
Query: 368 LGKGDYFGELALVTHKPRAASVYAIGATKVAFLDVETFERLLGPCMEIMKRNIDXY 201
LG DYFGE+AL+ ++PRAA+V A G K LD FER+LGPC +I+KRNI Y
Sbjct: 318 LGPSDYFGEIALLMNRPRAATVVARGPLKCVKLDRPRFERVLGPCSDILKRNIQQY 373
Score = 69.7 bits (163), Expect = 1e-11
Identities = 44/153 (28%), Positives = 76/153 (49%)
Frame = -1
Query: 638 DRHTFRRILLKSAFKKRKLYEELLDKVPMLKALQPYERANLADALLPRTLVEGELIIRQG 459
D ++ R ++ +K + ++K + L ER+++ DA+ + + GE +I+QG
Sbjct: 109 DAASYVRKVIPKDYKTMAALAKAIEKNVLFSHLDDNERSDIFDAMFSVSFIAGETVIQQG 168
Query: 458 DTADGMYFVEDGSVSIRITRDDGNEHEIKRLGKGDYFGELALVTHKPRAASVYAIGATKV 279
D D Y ++ G + + N +G+G FGELAL+ PRAA+V A K+
Sbjct: 169 DEGDNFYVIDQGETDVYV-----NNEWATSVGEGGSFGELALIYGTPRAATVKAKTNVKL 223
Query: 278 AFLDVETFERLLGPCMEIMKRNIDXYEEQLVKL 180
+D +++ R+L M R YEE L K+
Sbjct: 224 WGIDRDSYRRIL---MGSTLRKRKMYEEFLSKV 253
Score = 31.1 bits (67), Expect = 4.7
Identities = 17/39 (43%), Positives = 21/39 (53%)
Frame = -1
Query: 728 SGSFGEXAXMYNMPRAAXVRAQTAGALWAMDRHTFRRIL 612
S FGE A + N PRAA V A+ +DR F R+L
Sbjct: 321 SDYFGEIALLMNRPRAATVVARGPLKCVKLDRPRFERVL 359
>AC004492-1|AAC08318.1| 112|Homo sapiens CAMP-DEPENDENT PROTEIN
KINASE TYPE II-BETA REGULATORY CHAIN protein.
Length = 112
Score = 120 bits (289), Expect = 6e-27
Identities = 60/109 (55%), Positives = 73/109 (66%), Gaps = 6/109 (5%)
Frame = -1
Query: 461 GDTADGMYFVEDGSVSIRITR------DDGNEHEIKRLGKGDYFGELALVTHKPRAASVY 300
GD+AD + VE G V I + R ++ EI R +G YFGELALVT+KPRAAS +
Sbjct: 1 GDSADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCSRGQYFGELALVTNKPRAASAH 60
Query: 299 AIGATKVAFLDVETFERLLGPCMEIMKRNIDXYEEQLVKLFGDKSNLTD 153
AIG K +DV+ FERLLGPCMEIMKRNI YEEQLV LFG ++ +
Sbjct: 61 AIGTVKCLAMDVQAFERLLGPCMEIMKRNIATYEEQLVALFGTNMDIVE 109
>Z92868-1|CAB07437.1| 686|Homo sapiens cGMP-dependent protein
kinase type I beta protein.
Length = 686
Score = 103 bits (248), Expect = 5e-22
Identities = 60/177 (33%), Positives = 91/177 (51%), Gaps = 3/177 (1%)
Frame = -1
Query: 719 FGEXAXMYNMPRAAXVRAQTAGALWAMDRHTFRRILLKSAFKKRKLYEELLDKVPMLKAL 540
FGE A +YN R A V+ LWA+DR F+ I++++ K Y E L VP ++L
Sbjct: 181 FGELAILYNCTRTATVKTLVNVKLWAIDRQCFQTIMMRTGLIKHTEYMEFLKSVPTFQSL 240
Query: 539 QPYERANLADALLPRTLVEGELIIRQGDTADGMYFVEDGSVSIRITRDDGNEHE---IKR 369
+ LAD L GE IIRQG D + + G+V+ +TR+D + ++
Sbjct: 241 PEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVN--VTREDSPSEDPVFLRT 298
Query: 368 LGKGDYFGELALVTHKPRAASVYAIGATKVAFLDVETFERLLGPCMEIMKRNIDXYE 198
LGKGD+FGE AL R A+V A A +D ++F+ L+G ++ + + E
Sbjct: 299 LGKGDWFGEKALQGEDVRTANVIAAEAVTCLVIDRDSFKHLIGGLDDVSNKAYEDAE 355
Score = 48.4 bits (110), Expect = 3e-05
Identities = 33/122 (27%), Positives = 62/122 (50%)
Frame = -1
Query: 608 KSAFKKRKLYEELLDKVPMLKALQPYERANLADALLPRTLVEGELIIRQGDTADGMYFVE 429
KS K + E +LD +K L+ + + D + P + II++GD +Y +E
Sbjct: 101 KSPQSKDLIKEAILDN-DFMKNLELSQIQEIVDCMYPVEYGKDSCIIKEGDVGSLVYVME 159
Query: 428 DGSVSIRITRDDGNEHEIKRLGKGDYFGELALVTHKPRAASVYAIGATKVAFLDVETFER 249
DG V +T++ ++ +G G FGELA++ + R A+V + K+ +D + F+
Sbjct: 160 DGKV--EVTKEG---VKLCTMGPGKVFGELAILYNCTRTATVKTLVNVKLWAIDRQCFQT 214
Query: 248 LL 243
++
Sbjct: 215 IM 216
>Z92867-1|CAB07436.1| 671|Homo sapiens cGMP-dependent protein
kinase type I alpha protein.
Length = 671
Score = 103 bits (248), Expect = 5e-22
Identities = 60/177 (33%), Positives = 91/177 (51%), Gaps = 3/177 (1%)
Frame = -1
Query: 719 FGEXAXMYNMPRAAXVRAQTAGALWAMDRHTFRRILLKSAFKKRKLYEELLDKVPMLKAL 540
FGE A +YN R A V+ LWA+DR F+ I++++ K Y E L VP ++L
Sbjct: 166 FGELAILYNCTRTATVKTLVNVKLWAIDRQCFQTIMMRTGLIKHTEYMEFLKSVPTFQSL 225
Query: 539 QPYERANLADALLPRTLVEGELIIRQGDTADGMYFVEDGSVSIRITRDDGNEHE---IKR 369
+ LAD L GE IIRQG D + + G+V+ +TR+D + ++
Sbjct: 226 PEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVN--VTREDSPSEDPVFLRT 283
Query: 368 LGKGDYFGELALVTHKPRAASVYAIGATKVAFLDVETFERLLGPCMEIMKRNIDXYE 198
LGKGD+FGE AL R A+V A A +D ++F+ L+G ++ + + E
Sbjct: 284 LGKGDWFGEKALQGEDVRTANVIAAEAVTCLVIDRDSFKHLIGGLDDVSNKAYEDAE 340
Score = 50.8 bits (116), Expect = 5e-06
Identities = 36/131 (27%), Positives = 66/131 (50%)
Frame = -1
Query: 635 RHTFRRILLKSAFKKRKLYEELLDKVPMLKALQPYERANLADALLPRTLVEGELIIRQGD 456
R FR+ KS K + E +LD +K L+ + + D + P + II++GD
Sbjct: 78 RQAFRKFT-KSERSKDLIKEAILDN-DFMKNLELSQIQEIVDCMYPVEYGKDSCIIKEGD 135
Query: 455 TADGMYFVEDGSVSIRITRDDGNEHEIKRLGKGDYFGELALVTHKPRAASVYAIGATKVA 276
+Y +EDG V +T++ ++ +G G FGELA++ + R A+V + K+
Sbjct: 136 VGSLVYVMEDGKV--EVTKEG---VKLCTMGPGKVFGELAILYNCTRTATVKTLVNVKLW 190
Query: 275 FLDVETFERLL 243
+D + F+ ++
Sbjct: 191 AIDRQCFQTIM 201
>Y07512-1|CAA68810.1| 686|Homo sapiens protein ( Human mRNA for
type I beta cGMP-dependent protein kinase (EC
2.7.1.37). ).
Length = 686
Score = 103 bits (248), Expect = 5e-22
Identities = 60/177 (33%), Positives = 91/177 (51%), Gaps = 3/177 (1%)
Frame = -1
Query: 719 FGEXAXMYNMPRAAXVRAQTAGALWAMDRHTFRRILLKSAFKKRKLYEELLDKVPMLKAL 540
FGE A +YN R A V+ LWA+DR F+ I++++ K Y E L VP ++L
Sbjct: 181 FGELAILYNCTRTATVKTLVNVKLWAIDRQCFQTIMMRTGLIKHTEYMEFLKSVPTFQSL 240
Query: 539 QPYERANLADALLPRTLVEGELIIRQGDTADGMYFVEDGSVSIRITRDDGNEHE---IKR 369
+ LAD L GE IIRQG D + + G+V+ +TR+D + ++
Sbjct: 241 PEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVN--VTREDSPSEDPVFLRT 298
Query: 368 LGKGDYFGELALVTHKPRAASVYAIGATKVAFLDVETFERLLGPCMEIMKRNIDXYE 198
LGKGD+FGE AL R A+V A A +D ++F+ L+G ++ + + E
Sbjct: 299 LGKGDWFGEKALQGEDVRTANVIAAEAVTCLVIDRDSFKHLIGGLDDVSNKAYEDAE 355
Score = 48.4 bits (110), Expect = 3e-05
Identities = 33/122 (27%), Positives = 62/122 (50%)
Frame = -1
Query: 608 KSAFKKRKLYEELLDKVPMLKALQPYERANLADALLPRTLVEGELIIRQGDTADGMYFVE 429
KS K + E +LD +K L+ + + D + P + II++GD +Y +E
Sbjct: 101 KSPQSKDLIKEAILDN-DFMKNLELSQIQEIVDCMYPVEYGKDSCIIKEGDVGSLVYVME 159
Query: 428 DGSVSIRITRDDGNEHEIKRLGKGDYFGELALVTHKPRAASVYAIGATKVAFLDVETFER 249
DG V +T++ ++ +G G FGELA++ + R A+V + K+ +D + F+
Sbjct: 160 DGKV--EVTKEG---VKLCTMGPGKVFGELAILYNCTRTATVKTLVNVKLWAIDRQCFQT 214
Query: 248 LL 243
++
Sbjct: 215 IM 216
>EF560730-1|ABQ59040.1| 686|Homo sapiens PRKG1 protein protein.
Length = 686
Score = 103 bits (248), Expect = 5e-22
Identities = 60/177 (33%), Positives = 91/177 (51%), Gaps = 3/177 (1%)
Frame = -1
Query: 719 FGEXAXMYNMPRAAXVRAQTAGALWAMDRHTFRRILLKSAFKKRKLYEELLDKVPMLKAL 540
FGE A +YN R A V+ LWA+DR F+ I++++ K Y E L VP ++L
Sbjct: 181 FGELAILYNCTRTATVKTLVNVKLWAIDRQCFQTIMMRTGLIKHTEYMEFLKSVPTFQSL 240
Query: 539 QPYERANLADALLPRTLVEGELIIRQGDTADGMYFVEDGSVSIRITRDDGNEHE---IKR 369
+ LAD L GE IIRQG D + + G+V+ +TR+D + ++
Sbjct: 241 PEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVN--VTREDSPSEDPVFLRT 298
Query: 368 LGKGDYFGELALVTHKPRAASVYAIGATKVAFLDVETFERLLGPCMEIMKRNIDXYE 198
LGKGD+FGE AL R A+V A A +D ++F+ L+G ++ + + E
Sbjct: 299 LGKGDWFGEKALQGEDVRTANVIAAEAVTCLVIDRDSFKHLIGGLDDVSNKAYEDAE 355
Score = 49.6 bits (113), Expect = 1e-05
Identities = 33/122 (27%), Positives = 62/122 (50%)
Frame = -1
Query: 608 KSAFKKRKLYEELLDKVPMLKALQPYERANLADALLPRTLVEGELIIRQGDTADGMYFVE 429
KS K + E +LD +K L+ + + D + P + II++GD +Y +E
Sbjct: 101 KSPQSKDLIKEAILDN-DFMKNLELSQIQEIVDCMYPVEYGKDSCIIKEGDVGSLVYVME 159
Query: 428 DGSVSIRITRDDGNEHEIKRLGKGDYFGELALVTHKPRAASVYAIGATKVAFLDVETFER 249
DG V +T++ ++ +G G FGELA++ + R A+V + K+ +D + F+
Sbjct: 160 DGKV--EVTKEGA---KLCTMGPGKVFGELAILYNCTRTATVKTLVNVKLWAIDRQCFQT 214
Query: 248 LL 243
++
Sbjct: 215 IM 216
>D45864-1|BAA08297.1| 671|Homo sapiens cGMP-dependent protein
kinase type I alpha protein.
Length = 671
Score = 103 bits (248), Expect = 5e-22
Identities = 60/177 (33%), Positives = 91/177 (51%), Gaps = 3/177 (1%)
Frame = -1
Query: 719 FGEXAXMYNMPRAAXVRAQTAGALWAMDRHTFRRILLKSAFKKRKLYEELLDKVPMLKAL 540
FGE A +YN R A V+ LWA+DR F+ I++++ K Y E L VP ++L
Sbjct: 166 FGELAILYNCTRTATVKTLVNVKLWAIDRQCFQTIMMRTGLIKHTEYMEFLKSVPTFQSL 225
Query: 539 QPYERANLADALLPRTLVEGELIIRQGDTADGMYFVEDGSVSIRITRDDGNEHE---IKR 369
+ LAD L GE IIRQG D + + G+V+ +TR+D + ++
Sbjct: 226 PEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVN--VTREDSPSEDPVFLRT 283
Query: 368 LGKGDYFGELALVTHKPRAASVYAIGATKVAFLDVETFERLLGPCMEIMKRNIDXYE 198
LGKGD+FGE AL R A+V A A +D ++F+ L+G ++ + + E
Sbjct: 284 LGKGDWFGEKALQGEDVRTANVIAAEAVTCLVIDRDSFKHLIGGLDDVSNKAYEDAE 340
Score = 50.8 bits (116), Expect = 5e-06
Identities = 36/131 (27%), Positives = 66/131 (50%)
Frame = -1
Query: 635 RHTFRRILLKSAFKKRKLYEELLDKVPMLKALQPYERANLADALLPRTLVEGELIIRQGD 456
R FR+ KS K + E +LD +K L+ + + D + P + II++GD
Sbjct: 78 RQAFRKFT-KSERSKDLIKEAILDN-DFMKNLELSQIQEIVDCMYPVEYGKDSCIIKEGD 135
Query: 455 TADGMYFVEDGSVSIRITRDDGNEHEIKRLGKGDYFGELALVTHKPRAASVYAIGATKVA 276
+Y +EDG V +T++ ++ +G G FGELA++ + R A+V + K+
Sbjct: 136 VGSLVYVMEDGKV--EVTKEG---VKLCTMGPGKVFGELAILYNCTRTATVKTLVNVKLW 190
Query: 275 FLDVETFERLL 243
+D + F+ ++
Sbjct: 191 AIDRQCFQTIM 201
>BC127090-1|AAI27091.1| 686|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 686
Score = 103 bits (248), Expect = 5e-22
Identities = 60/177 (33%), Positives = 91/177 (51%), Gaps = 3/177 (1%)
Frame = -1
Query: 719 FGEXAXMYNMPRAAXVRAQTAGALWAMDRHTFRRILLKSAFKKRKLYEELLDKVPMLKAL 540
FGE A +YN R A V+ LWA+DR F+ I++++ K Y E L VP ++L
Sbjct: 181 FGELAILYNCTRTATVKTLVNVKLWAIDRQCFQTIMMRTGLIKHTEYMEFLKSVPTFQSL 240
Query: 539 QPYERANLADALLPRTLVEGELIIRQGDTADGMYFVEDGSVSIRITRDDGNEHE---IKR 369
+ LAD L GE IIRQG D + + G+V+ +TR+D + ++
Sbjct: 241 PEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVN--VTREDSPSEDPVFLRT 298
Query: 368 LGKGDYFGELALVTHKPRAASVYAIGATKVAFLDVETFERLLGPCMEIMKRNIDXYE 198
LGKGD+FGE AL R A+V A A +D ++F+ L+G ++ + + E
Sbjct: 299 LGKGDWFGEKALQGEDVRTANVIAAEAVTCLVIDRDSFKHLIGGLDDVSNKAYEDAE 355
Score = 48.4 bits (110), Expect = 3e-05
Identities = 33/122 (27%), Positives = 62/122 (50%)
Frame = -1
Query: 608 KSAFKKRKLYEELLDKVPMLKALQPYERANLADALLPRTLVEGELIIRQGDTADGMYFVE 429
KS K + E +LD +K L+ + + D + P + II++GD +Y +E
Sbjct: 101 KSPQSKDLIKEAILDN-DFMKNLELSQIQEIVDCMYPVEYGKDSCIIKEGDVGSLVYVME 159
Query: 428 DGSVSIRITRDDGNEHEIKRLGKGDYFGELALVTHKPRAASVYAIGATKVAFLDVETFER 249
DG V +T++ ++ +G G FGELA++ + R A+V + K+ +D + F+
Sbjct: 160 DGKV--EVTKEG---VKLCTMGPGKVFGELAILYNCTRTATVKTLVNVKLWAIDRQCFQT 214
Query: 248 LL 243
++
Sbjct: 215 IM 216
>AL928686-2|CAI40743.1| 686|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 686
Score = 103 bits (248), Expect = 5e-22
Identities = 60/177 (33%), Positives = 91/177 (51%), Gaps = 3/177 (1%)
Frame = -1
Query: 719 FGEXAXMYNMPRAAXVRAQTAGALWAMDRHTFRRILLKSAFKKRKLYEELLDKVPMLKAL 540
FGE A +YN R A V+ LWA+DR F+ I++++ K Y E L VP ++L
Sbjct: 181 FGELAILYNCTRTATVKTLVNVKLWAIDRQCFQTIMMRTGLIKHTEYMEFLKSVPTFQSL 240
Query: 539 QPYERANLADALLPRTLVEGELIIRQGDTADGMYFVEDGSVSIRITRDDGNEHE---IKR 369
+ LAD L GE IIRQG D + + G+V+ +TR+D + ++
Sbjct: 241 PEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVN--VTREDSPSEDPVFLRT 298
Query: 368 LGKGDYFGELALVTHKPRAASVYAIGATKVAFLDVETFERLLGPCMEIMKRNIDXYE 198
LGKGD+FGE AL R A+V A A +D ++F+ L+G ++ + + E
Sbjct: 299 LGKGDWFGEKALQGEDVRTANVIAAEAVTCLVIDRDSFKHLIGGLDDVSNKAYEDAE 355
Score = 48.4 bits (110), Expect = 3e-05
Identities = 33/122 (27%), Positives = 62/122 (50%)
Frame = -1
Query: 608 KSAFKKRKLYEELLDKVPMLKALQPYERANLADALLPRTLVEGELIIRQGDTADGMYFVE 429
KS K + E +LD +K L+ + + D + P + II++GD +Y +E
Sbjct: 101 KSPQSKDLIKEAILDN-DFMKNLELSQIQEIVDCMYPVEYGKDSCIIKEGDVGSLVYVME 159
Query: 428 DGSVSIRITRDDGNEHEIKRLGKGDYFGELALVTHKPRAASVYAIGATKVAFLDVETFER 249
DG V +T++ ++ +G G FGELA++ + R A+V + K+ +D + F+
Sbjct: 160 DGKV--EVTKEG---VKLCTMGPGKVFGELAILYNCTRTATVKTLVNVKLWAIDRQCFQT 214
Query: 248 LL 243
++
Sbjct: 215 IM 216
>AL928686-1|CAI40742.1| 659|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 659
Score = 103 bits (248), Expect = 5e-22
Identities = 60/177 (33%), Positives = 91/177 (51%), Gaps = 3/177 (1%)
Frame = -1
Query: 719 FGEXAXMYNMPRAAXVRAQTAGALWAMDRHTFRRILLKSAFKKRKLYEELLDKVPMLKAL 540
FGE A +YN R A V+ LWA+DR F+ I++++ K Y E L VP ++L
Sbjct: 154 FGELAILYNCTRTATVKTLVNVKLWAIDRQCFQTIMMRTGLIKHTEYMEFLKSVPTFQSL 213
Query: 539 QPYERANLADALLPRTLVEGELIIRQGDTADGMYFVEDGSVSIRITRDDGNEHE---IKR 369
+ LAD L GE IIRQG D + + G+V+ +TR+D + ++
Sbjct: 214 PEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVN--VTREDSPSEDPVFLRT 271
Query: 368 LGKGDYFGELALVTHKPRAASVYAIGATKVAFLDVETFERLLGPCMEIMKRNIDXYE 198
LGKGD+FGE AL R A+V A A +D ++F+ L+G ++ + + E
Sbjct: 272 LGKGDWFGEKALQGEDVRTANVIAAEAVTCLVIDRDSFKHLIGGLDDVSNKAYEDAE 328
Score = 50.8 bits (116), Expect = 5e-06
Identities = 36/131 (27%), Positives = 66/131 (50%)
Frame = -1
Query: 635 RHTFRRILLKSAFKKRKLYEELLDKVPMLKALQPYERANLADALLPRTLVEGELIIRQGD 456
R FR+ KS K + E +LD +K L+ + + D + P + II++GD
Sbjct: 66 RQAFRKFT-KSERSKDLIKEAILDN-DFMKNLELSQIQEIVDCMYPVEYGKDSCIIKEGD 123
Query: 455 TADGMYFVEDGSVSIRITRDDGNEHEIKRLGKGDYFGELALVTHKPRAASVYAIGATKVA 276
+Y +EDG V +T++ ++ +G G FGELA++ + R A+V + K+
Sbjct: 124 VGSLVYVMEDGKV--EVTKEG---VKLCTMGPGKVFGELAILYNCTRTATVKTLVNVKLW 178
Query: 275 FLDVETFERLL 243
+D + F+ ++
Sbjct: 179 AIDRQCFQTIM 189
>AL731537-3|CAI17115.1| 686|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 686
Score = 103 bits (248), Expect = 5e-22
Identities = 60/177 (33%), Positives = 91/177 (51%), Gaps = 3/177 (1%)
Frame = -1
Query: 719 FGEXAXMYNMPRAAXVRAQTAGALWAMDRHTFRRILLKSAFKKRKLYEELLDKVPMLKAL 540
FGE A +YN R A V+ LWA+DR F+ I++++ K Y E L VP ++L
Sbjct: 181 FGELAILYNCTRTATVKTLVNVKLWAIDRQCFQTIMMRTGLIKHTEYMEFLKSVPTFQSL 240
Query: 539 QPYERANLADALLPRTLVEGELIIRQGDTADGMYFVEDGSVSIRITRDDGNEHE---IKR 369
+ LAD L GE IIRQG D + + G+V+ +TR+D + ++
Sbjct: 241 PEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVN--VTREDSPSEDPVFLRT 298
Query: 368 LGKGDYFGELALVTHKPRAASVYAIGATKVAFLDVETFERLLGPCMEIMKRNIDXYE 198
LGKGD+FGE AL R A+V A A +D ++F+ L+G ++ + + E
Sbjct: 299 LGKGDWFGEKALQGEDVRTANVIAAEAVTCLVIDRDSFKHLIGGLDDVSNKAYEDAE 355
Score = 48.4 bits (110), Expect = 3e-05
Identities = 33/122 (27%), Positives = 62/122 (50%)
Frame = -1
Query: 608 KSAFKKRKLYEELLDKVPMLKALQPYERANLADALLPRTLVEGELIIRQGDTADGMYFVE 429
KS K + E +LD +K L+ + + D + P + II++GD +Y +E
Sbjct: 101 KSPQSKDLIKEAILDN-DFMKNLELSQIQEIVDCMYPVEYGKDSCIIKEGDVGSLVYVME 159
Query: 428 DGSVSIRITRDDGNEHEIKRLGKGDYFGELALVTHKPRAASVYAIGATKVAFLDVETFER 249
DG V +T++ ++ +G G FGELA++ + R A+V + K+ +D + F+
Sbjct: 160 DGKV--EVTKEG---VKLCTMGPGKVFGELAILYNCTRTATVKTLVNVKLWAIDRQCFQT 214
Query: 248 LL 243
++
Sbjct: 215 IM 216
>AL731537-2|CAI17114.1| 659|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 659
Score = 103 bits (248), Expect = 5e-22
Identities = 60/177 (33%), Positives = 91/177 (51%), Gaps = 3/177 (1%)
Frame = -1
Query: 719 FGEXAXMYNMPRAAXVRAQTAGALWAMDRHTFRRILLKSAFKKRKLYEELLDKVPMLKAL 540
FGE A +YN R A V+ LWA+DR F+ I++++ K Y E L VP ++L
Sbjct: 154 FGELAILYNCTRTATVKTLVNVKLWAIDRQCFQTIMMRTGLIKHTEYMEFLKSVPTFQSL 213
Query: 539 QPYERANLADALLPRTLVEGELIIRQGDTADGMYFVEDGSVSIRITRDDGNEHE---IKR 369
+ LAD L GE IIRQG D + + G+V+ +TR+D + ++
Sbjct: 214 PEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVN--VTREDSPSEDPVFLRT 271
Query: 368 LGKGDYFGELALVTHKPRAASVYAIGATKVAFLDVETFERLLGPCMEIMKRNIDXYE 198
LGKGD+FGE AL R A+V A A +D ++F+ L+G ++ + + E
Sbjct: 272 LGKGDWFGEKALQGEDVRTANVIAAEAVTCLVIDRDSFKHLIGGLDDVSNKAYEDAE 328
Score = 50.8 bits (116), Expect = 5e-06
Identities = 36/131 (27%), Positives = 66/131 (50%)
Frame = -1
Query: 635 RHTFRRILLKSAFKKRKLYEELLDKVPMLKALQPYERANLADALLPRTLVEGELIIRQGD 456
R FR+ KS K + E +LD +K L+ + + D + P + II++GD
Sbjct: 66 RQAFRKFT-KSERSKDLIKEAILDN-DFMKNLELSQIQEIVDCMYPVEYGKDSCIIKEGD 123
Query: 455 TADGMYFVEDGSVSIRITRDDGNEHEIKRLGKGDYFGELALVTHKPRAASVYAIGATKVA 276
+Y +EDG V +T++ ++ +G G FGELA++ + R A+V + K+
Sbjct: 124 VGSLVYVMEDGKV--EVTKEG---VKLCTMGPGKVFGELAILYNCTRTATVKTLVNVKLW 178
Query: 275 FLDVETFERLL 243
+D + F+ ++
Sbjct: 179 AIDRQCFQTIM 189
>AL391378-2|CAI39626.1| 686|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 686
Score = 103 bits (248), Expect = 5e-22
Identities = 60/177 (33%), Positives = 91/177 (51%), Gaps = 3/177 (1%)
Frame = -1
Query: 719 FGEXAXMYNMPRAAXVRAQTAGALWAMDRHTFRRILLKSAFKKRKLYEELLDKVPMLKAL 540
FGE A +YN R A V+ LWA+DR F+ I++++ K Y E L VP ++L
Sbjct: 181 FGELAILYNCTRTATVKTLVNVKLWAIDRQCFQTIMMRTGLIKHTEYMEFLKSVPTFQSL 240
Query: 539 QPYERANLADALLPRTLVEGELIIRQGDTADGMYFVEDGSVSIRITRDDGNEHE---IKR 369
+ LAD L GE IIRQG D + + G+V+ +TR+D + ++
Sbjct: 241 PEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVN--VTREDSPSEDPVFLRT 298
Query: 368 LGKGDYFGELALVTHKPRAASVYAIGATKVAFLDVETFERLLGPCMEIMKRNIDXYE 198
LGKGD+FGE AL R A+V A A +D ++F+ L+G ++ + + E
Sbjct: 299 LGKGDWFGEKALQGEDVRTANVIAAEAVTCLVIDRDSFKHLIGGLDDVSNKAYEDAE 355
Score = 48.4 bits (110), Expect = 3e-05
Identities = 33/122 (27%), Positives = 62/122 (50%)
Frame = -1
Query: 608 KSAFKKRKLYEELLDKVPMLKALQPYERANLADALLPRTLVEGELIIRQGDTADGMYFVE 429
KS K + E +LD +K L+ + + D + P + II++GD +Y +E
Sbjct: 101 KSPQSKDLIKEAILDN-DFMKNLELSQIQEIVDCMYPVEYGKDSCIIKEGDVGSLVYVME 159
Query: 428 DGSVSIRITRDDGNEHEIKRLGKGDYFGELALVTHKPRAASVYAIGATKVAFLDVETFER 249
DG V +T++ ++ +G G FGELA++ + R A+V + K+ +D + F+
Sbjct: 160 DGKV--EVTKEG---VKLCTMGPGKVFGELAILYNCTRTATVKTLVNVKLWAIDRQCFQT 214
Query: 248 LL 243
++
Sbjct: 215 IM 216
>AL391378-1|CAI39625.1| 659|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 659
Score = 103 bits (248), Expect = 5e-22
Identities = 60/177 (33%), Positives = 91/177 (51%), Gaps = 3/177 (1%)
Frame = -1
Query: 719 FGEXAXMYNMPRAAXVRAQTAGALWAMDRHTFRRILLKSAFKKRKLYEELLDKVPMLKAL 540
FGE A +YN R A V+ LWA+DR F+ I++++ K Y E L VP ++L
Sbjct: 154 FGELAILYNCTRTATVKTLVNVKLWAIDRQCFQTIMMRTGLIKHTEYMEFLKSVPTFQSL 213
Query: 539 QPYERANLADALLPRTLVEGELIIRQGDTADGMYFVEDGSVSIRITRDDGNEHE---IKR 369
+ LAD L GE IIRQG D + + G+V+ +TR+D + ++
Sbjct: 214 PEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVN--VTREDSPSEDPVFLRT 271
Query: 368 LGKGDYFGELALVTHKPRAASVYAIGATKVAFLDVETFERLLGPCMEIMKRNIDXYE 198
LGKGD+FGE AL R A+V A A +D ++F+ L+G ++ + + E
Sbjct: 272 LGKGDWFGEKALQGEDVRTANVIAAEAVTCLVIDRDSFKHLIGGLDDVSNKAYEDAE 328
Score = 50.8 bits (116), Expect = 5e-06
Identities = 36/131 (27%), Positives = 66/131 (50%)
Frame = -1
Query: 635 RHTFRRILLKSAFKKRKLYEELLDKVPMLKALQPYERANLADALLPRTLVEGELIIRQGD 456
R FR+ KS K + E +LD +K L+ + + D + P + II++GD
Sbjct: 66 RQAFRKFT-KSERSKDLIKEAILDN-DFMKNLELSQIQEIVDCMYPVEYGKDSCIIKEGD 123
Query: 455 TADGMYFVEDGSVSIRITRDDGNEHEIKRLGKGDYFGELALVTHKPRAASVYAIGATKVA 276
+Y +EDG V +T++ ++ +G G FGELA++ + R A+V + K+
Sbjct: 124 VGSLVYVMEDGKV--EVTKEG---VKLCTMGPGKVFGELAILYNCTRTATVKTLVNVKLW 178
Query: 275 FLDVETFERLL 243
+D + F+ ++
Sbjct: 179 AIDRQCFQTIM 189
>AL157399-2|CAI41305.1| 686|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 686
Score = 103 bits (248), Expect = 5e-22
Identities = 60/177 (33%), Positives = 91/177 (51%), Gaps = 3/177 (1%)
Frame = -1
Query: 719 FGEXAXMYNMPRAAXVRAQTAGALWAMDRHTFRRILLKSAFKKRKLYEELLDKVPMLKAL 540
FGE A +YN R A V+ LWA+DR F+ I++++ K Y E L VP ++L
Sbjct: 181 FGELAILYNCTRTATVKTLVNVKLWAIDRQCFQTIMMRTGLIKHTEYMEFLKSVPTFQSL 240
Query: 539 QPYERANLADALLPRTLVEGELIIRQGDTADGMYFVEDGSVSIRITRDDGNEHE---IKR 369
+ LAD L GE IIRQG D + + G+V+ +TR+D + ++
Sbjct: 241 PEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVN--VTREDSPSEDPVFLRT 298
Query: 368 LGKGDYFGELALVTHKPRAASVYAIGATKVAFLDVETFERLLGPCMEIMKRNIDXYE 198
LGKGD+FGE AL R A+V A A +D ++F+ L+G ++ + + E
Sbjct: 299 LGKGDWFGEKALQGEDVRTANVIAAEAVTCLVIDRDSFKHLIGGLDDVSNKAYEDAE 355
Score = 48.4 bits (110), Expect = 3e-05
Identities = 33/122 (27%), Positives = 62/122 (50%)
Frame = -1
Query: 608 KSAFKKRKLYEELLDKVPMLKALQPYERANLADALLPRTLVEGELIIRQGDTADGMYFVE 429
KS K + E +LD +K L+ + + D + P + II++GD +Y +E
Sbjct: 101 KSPQSKDLIKEAILDN-DFMKNLELSQIQEIVDCMYPVEYGKDSCIIKEGDVGSLVYVME 159
Query: 428 DGSVSIRITRDDGNEHEIKRLGKGDYFGELALVTHKPRAASVYAIGATKVAFLDVETFER 249
DG V +T++ ++ +G G FGELA++ + R A+V + K+ +D + F+
Sbjct: 160 DGKV--EVTKEG---VKLCTMGPGKVFGELAILYNCTRTATVKTLVNVKLWAIDRQCFQT 214
Query: 248 LL 243
++
Sbjct: 215 IM 216
>AL157399-1|CAI41304.1| 659|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 659
Score = 103 bits (248), Expect = 5e-22
Identities = 60/177 (33%), Positives = 91/177 (51%), Gaps = 3/177 (1%)
Frame = -1
Query: 719 FGEXAXMYNMPRAAXVRAQTAGALWAMDRHTFRRILLKSAFKKRKLYEELLDKVPMLKAL 540
FGE A +YN R A V+ LWA+DR F+ I++++ K Y E L VP ++L
Sbjct: 154 FGELAILYNCTRTATVKTLVNVKLWAIDRQCFQTIMMRTGLIKHTEYMEFLKSVPTFQSL 213
Query: 539 QPYERANLADALLPRTLVEGELIIRQGDTADGMYFVEDGSVSIRITRDDGNEHE---IKR 369
+ LAD L GE IIRQG D + + G+V+ +TR+D + ++
Sbjct: 214 PEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVN--VTREDSPSEDPVFLRT 271
Query: 368 LGKGDYFGELALVTHKPRAASVYAIGATKVAFLDVETFERLLGPCMEIMKRNIDXYE 198
LGKGD+FGE AL R A+V A A +D ++F+ L+G ++ + + E
Sbjct: 272 LGKGDWFGEKALQGEDVRTANVIAAEAVTCLVIDRDSFKHLIGGLDDVSNKAYEDAE 328
Score = 50.8 bits (116), Expect = 5e-06
Identities = 36/131 (27%), Positives = 66/131 (50%)
Frame = -1
Query: 635 RHTFRRILLKSAFKKRKLYEELLDKVPMLKALQPYERANLADALLPRTLVEGELIIRQGD 456
R FR+ KS K + E +LD +K L+ + + D + P + II++GD
Sbjct: 66 RQAFRKFT-KSERSKDLIKEAILDN-DFMKNLELSQIQEIVDCMYPVEYGKDSCIIKEGD 123
Query: 455 TADGMYFVEDGSVSIRITRDDGNEHEIKRLGKGDYFGELALVTHKPRAASVYAIGATKVA 276
+Y +EDG V +T++ ++ +G G FGELA++ + R A+V + K+
Sbjct: 124 VGSLVYVMEDGKV--EVTKEG---VKLCTMGPGKVFGELAILYNCTRTATVKTLVNVKLW 178
Query: 275 FLDVETFERLL 243
+D + F+ ++
Sbjct: 179 AIDRQCFQTIM 189
>AC006387-1|AAS07389.1| 306|Homo sapiens unknown protein.
Length = 306
Score = 101 bits (243), Expect = 2e-21
Identities = 48/101 (47%), Positives = 66/101 (65%)
Frame = -1
Query: 764 DRVEKVVHTYEGSGSFGEXAXMYNMPRAAXVRAQTAGALWAMDRHTFRRILLKSAFKKRK 585
D V + V Y+ GSFGE A MYN PRAA + A + GALW +DR TFRRI++K+ KKRK
Sbjct: 206 DGVGRCVGNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFRRIIVKNNAKKRK 265
Query: 584 LYEELLDKVPMLKALQPYERANLADALLPRTLVEGELIIRQ 462
+YE ++ +P LK+L+ ER + D + + +GE II Q
Sbjct: 266 MYESFIESLPFLKSLEFSERLKVVDVIGTKVYNDGEQIIAQ 306
Score = 63.3 bits (147), Expect = 9e-10
Identities = 37/126 (29%), Positives = 63/126 (50%)
Frame = -1
Query: 620 RILLKSAFKKRKLYEELLDKVPMLKALQPYERANLADALLPRTLVEGELIIRQGDTADGM 441
RI+ +R +E + + K L P + + + DA+ + + +GE +I QGD D
Sbjct: 132 RIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKDGEHVIDQGDDGDNF 191
Query: 440 YFVEDGSVSIRITRDDGNEHEIKRLGKGDYFGELALVTHKPRAASVYAIGATKVAFLDVE 261
Y ++ G+ I + + DG + FGELAL+ + PRAA++ A + LD
Sbjct: 192 YVIDRGTFDIYV-KCDGVGRCVGNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRV 250
Query: 260 TFERLL 243
TF R++
Sbjct: 251 TFRRII 256
>Y16106-1|CAA76073.1| 734|Homo sapiens cGMP-dependant protein
kinase protein.
Length = 734
Score = 94.3 bits (224), Expect = 4e-19
Identities = 56/181 (30%), Positives = 94/181 (51%), Gaps = 2/181 (1%)
Frame = -1
Query: 755 EKVVHTYEGSGSFGEXAXMYNMPRAAXVRAQTAGALWAMDRHTFRRILLKSAFKKRKLYE 576
EK++ + +FGE A +YN R A V+A T WA+DR F+ I+ ++A + + Y
Sbjct: 219 EKLLSSIPMWTTFGELAILYNCTRTASVKAITNVKTWALDREVFQNIMRRTAQARDEQYR 278
Query: 575 ELLDKVPMLKALQPYERANLADALLPRTLVEGELIIRQGDTADGMYFVEDGSVSIRITRD 396
L V +LK L + + D L +G+ IIR+G+ + + G V + + +
Sbjct: 279 NFLRSVSLLKNLPEDKLTKIIDCLEVEYYDKGDYIIREGEEGSTFFILAKGKVKVTQSTE 338
Query: 395 DGNEHE-IKRLGKGDYFGELALVTHKPRAASVYA-IGATKVAFLDVETFERLLGPCMEIM 222
++ + IK L KG+YFGE AL++ R+A++ A +D ETF + +G E+
Sbjct: 339 GHDQPQLIKTLQKGEYFGEKALISDDVRSANIIAEENDVACLVIDRETFNQTVGTFEELQ 398
Query: 221 K 219
K
Sbjct: 399 K 399
>X94612-1|CAA64318.1| 762|Homo sapiens Type II cGMP-dependent
protein kinase protein.
Length = 762
Score = 94.3 bits (224), Expect = 4e-19
Identities = 56/181 (30%), Positives = 94/181 (51%), Gaps = 2/181 (1%)
Frame = -1
Query: 755 EKVVHTYEGSGSFGEXAXMYNMPRAAXVRAQTAGALWAMDRHTFRRILLKSAFKKRKLYE 576
EK++ + +FGE A +YN R A V+A T WA+DR F+ I+ ++A + + Y
Sbjct: 219 EKLLSSIPMWTTFGELAILYNCTRTASVKAITNVKTWALDREVFQNIMRRTAQARDEQYR 278
Query: 575 ELLDKVPMLKALQPYERANLADALLPRTLVEGELIIRQGDTADGMYFVEDGSVSIRITRD 396
L V +LK L + + D L +G+ IIR+G+ + + G V + + +
Sbjct: 279 NFLRSVSLLKNLPEDKLTKIIDCLEVEYYDKGDYIIREGEEGSTFFILAKGKVKVTQSTE 338
Query: 395 DGNEHE-IKRLGKGDYFGELALVTHKPRAASVYA-IGATKVAFLDVETFERLLGPCMEIM 222
++ + IK L KG+YFGE AL++ R+A++ A +D ETF + +G E+
Sbjct: 339 GHDQPQLIKTLQKGEYFGEKALISDDVRSANIIAEENDVACLVIDRETFNQTVGTFEELQ 398
Query: 221 K 219
K
Sbjct: 399 K 399
>D70899-1|BAA18934.1| 762|Homo sapiens cGMP-dependent protein
kinase II protein.
Length = 762
Score = 94.3 bits (224), Expect = 4e-19
Identities = 56/181 (30%), Positives = 94/181 (51%), Gaps = 2/181 (1%)
Frame = -1
Query: 755 EKVVHTYEGSGSFGEXAXMYNMPRAAXVRAQTAGALWAMDRHTFRRILLKSAFKKRKLYE 576
EK++ + +FGE A +YN R A V+A T WA+DR F+ I+ ++A + + Y
Sbjct: 219 EKLLSSIPMWTTFGELAILYNCTRTASVKAITNVKTWALDREVFQNIMRRTAQARDEQYR 278
Query: 575 ELLDKVPMLKALQPYERANLADALLPRTLVEGELIIRQGDTADGMYFVEDGSVSIRITRD 396
L V +LK L + + D L +G+ IIR+G+ + + G V + + +
Sbjct: 279 NFLRSVSLLKNLPEDKLTKIIDCLEVEYYDKGDYIIREGEEGSTFFILAKGKVKVTQSTE 338
Query: 395 DGNEHE-IKRLGKGDYFGELALVTHKPRAASVYA-IGATKVAFLDVETFERLLGPCMEIM 222
++ + IK L KG+YFGE AL++ R+A++ A +D ETF + +G E+
Sbjct: 339 GHDQPQLIKTLQKGEYFGEKALISDDVRSANIIAEENDVACLVIDRETFNQTVGTFEELQ 398
Query: 221 K 219
K
Sbjct: 399 K 399
>BC062688-1|AAH62688.1| 312|Homo sapiens PRKG1 protein protein.
Length = 312
Score = 89.8 bits (213), Expect = 9e-18
Identities = 50/132 (37%), Positives = 71/132 (53%), Gaps = 3/132 (2%)
Frame = -1
Query: 719 FGEXAXMYNMPRAAXVRAQTAGALWAMDRHTFRRILLKSAFKKRKLYEELLDKVPMLKAL 540
FGE A +YN R A V+ LWA+DR F+ I++++ K Y E L VP ++L
Sbjct: 181 FGELAILYNCTRTATVKTLVNVKLWAIDRQCFQTIMMRTGLIKHTEYMEFLKSVPTFQSL 240
Query: 539 QPYERANLADALLPRTLVEGELIIRQGDTADGMYFVEDGSVSIRITRDDGNEHE---IKR 369
+ LAD L GE IIRQG D + + G+V+ +TR+D + ++
Sbjct: 241 PEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVN--VTREDSPSEDPVFLRT 298
Query: 368 LGKGDYFGELAL 333
LGKGD+FGE AL
Sbjct: 299 LGKGDWFGEKAL 310
Score = 48.4 bits (110), Expect = 3e-05
Identities = 33/122 (27%), Positives = 62/122 (50%)
Frame = -1
Query: 608 KSAFKKRKLYEELLDKVPMLKALQPYERANLADALLPRTLVEGELIIRQGDTADGMYFVE 429
KS K + E +LD +K L+ + + D + P + II++GD +Y +E
Sbjct: 101 KSPQSKDLIKEAILDN-DFMKNLELSQIQEIVDCMYPVEYGKDSCIIKEGDVGSLVYVME 159
Query: 428 DGSVSIRITRDDGNEHEIKRLGKGDYFGELALVTHKPRAASVYAIGATKVAFLDVETFER 249
DG V +T++ ++ +G G FGELA++ + R A+V + K+ +D + F+
Sbjct: 160 DGKV--EVTKEG---VKLCTMGPGKVFGELAILYNCTRTATVKTLVNVKLWAIDRQCFQT 214
Query: 248 LL 243
++
Sbjct: 215 IM 216
>AL391378-3|CAI39627.1| 181|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 181
Score = 89.8 bits (213), Expect = 9e-18
Identities = 50/132 (37%), Positives = 71/132 (53%), Gaps = 3/132 (2%)
Frame = -1
Query: 719 FGEXAXMYNMPRAAXVRAQTAGALWAMDRHTFRRILLKSAFKKRKLYEELLDKVPMLKAL 540
FGE A +YN R A V+ LWA+DR F+ I++++ K Y E L VP ++L
Sbjct: 39 FGELAILYNCTRTATVKTLVNVKLWAIDRQCFQTIMMRTGLIKHTEYMEFLKSVPTFQSL 98
Query: 539 QPYERANLADALLPRTLVEGELIIRQGDTADGMYFVEDGSVSIRITRDDGNEHE---IKR 369
+ LAD L GE IIRQG D + + G+V+ +TR+D + ++
Sbjct: 99 PEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVN--VTREDSPSEDPVFLRT 156
Query: 368 LGKGDYFGELAL 333
LGKGD+FGE AL
Sbjct: 157 LGKGDWFGEKAL 168
Score = 39.9 bits (89), Expect = 0.010
Identities = 23/77 (29%), Positives = 44/77 (57%)
Frame = -1
Query: 473 IIRQGDTADGMYFVEDGSVSIRITRDDGNEHEIKRLGKGDYFGELALVTHKPRAASVYAI 294
II++GD +Y +EDG V +T++ ++ +G G FGELA++ + R A+V +
Sbjct: 3 IIKEGDVGSLVYVMEDGKV--EVTKEG---VKLCTMGPGKVFGELAILYNCTRTATVKTL 57
Query: 293 GATKVAFLDVETFERLL 243
K+ +D + F+ ++
Sbjct: 58 VNVKLWAIDRQCFQTIM 74
>AL157399-3|CAI41306.1| 181|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 181
Score = 89.8 bits (213), Expect = 9e-18
Identities = 50/132 (37%), Positives = 71/132 (53%), Gaps = 3/132 (2%)
Frame = -1
Query: 719 FGEXAXMYNMPRAAXVRAQTAGALWAMDRHTFRRILLKSAFKKRKLYEELLDKVPMLKAL 540
FGE A +YN R A V+ LWA+DR F+ I++++ K Y E L VP ++L
Sbjct: 39 FGELAILYNCTRTATVKTLVNVKLWAIDRQCFQTIMMRTGLIKHTEYMEFLKSVPTFQSL 98
Query: 539 QPYERANLADALLPRTLVEGELIIRQGDTADGMYFVEDGSVSIRITRDDGNEHE---IKR 369
+ LAD L GE IIRQG D + + G+V+ +TR+D + ++
Sbjct: 99 PEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVN--VTREDSPSEDPVFLRT 156
Query: 368 LGKGDYFGELAL 333
LGKGD+FGE AL
Sbjct: 157 LGKGDWFGEKAL 168
Score = 39.9 bits (89), Expect = 0.010
Identities = 23/77 (29%), Positives = 44/77 (57%)
Frame = -1
Query: 473 IIRQGDTADGMYFVEDGSVSIRITRDDGNEHEIKRLGKGDYFGELALVTHKPRAASVYAI 294
II++GD +Y +EDG V +T++ ++ +G G FGELA++ + R A+V +
Sbjct: 3 IIKEGDVGSLVYVMEDGKV--EVTKEG---VKLCTMGPGKVFGELAILYNCTRTATVKTL 57
Query: 293 GATKVAFLDVETFERLL 243
K+ +D + F+ ++
Sbjct: 58 VNVKLWAIDRQCFQTIM 74
>L03357-1|AAA60266.1| 593|Homo sapiens RET tyrosine kinase/cAMP
protein kinase A subunit RI protein.
Length = 593
Score = 69.3 bits (162), Expect = 1e-11
Identities = 40/145 (27%), Positives = 74/145 (51%), Gaps = 2/145 (1%)
Frame = -1
Query: 638 DRHTFRRILLKSAFKKRKLYEELLDKVPMLKALQPYERANLADALLPRTLVEGELIIRQG 459
D ++ R ++ +K + ++K + L ER+++ DA+ + + GE +I+QG
Sbjct: 109 DAASYVRKVIPKDYKTMAALAKAIEKNVLFSHLDDNERSDIFDAMFSVSFIAGETVIQQG 168
Query: 458 DTADGMYFVEDGSVSIRITRDDGNEHEIKRLGKGDYFGELALVTHKPRAASVYAIGATKV 279
D D Y ++ G + + N +G+G FGELAL+ PRAA+V A K+
Sbjct: 169 DEGDNFYVIDQGETDVYV-----NNEWATSVGEGGSFGELALIYGTPRAATVKAKTNVKL 223
Query: 278 AFLDVETFERLL--GPCMEIMKRNI 210
+D +++ R+L P E ++N+
Sbjct: 224 WGIDRDSYRRILMEDPKWEFPRKNL 248
Score = 51.2 bits (117), Expect = 4e-06
Identities = 22/40 (55%), Positives = 30/40 (75%)
Frame = -1
Query: 725 GSFGEXAXMYNMPRAAXVRAQTAGALWAMDRHTFRRILLK 606
GSFGE A +Y PRAA V+A+T LW +DR ++RRIL++
Sbjct: 198 GSFGELALIYGTPRAATVKAKTNVKLWGIDRDSYRRILME 237
>BC070478-1|AAH70478.1| 80|Homo sapiens PRKAR1B protein protein.
Length = 80
Score = 58.4 bits (135), Expect = 3e-08
Identities = 26/60 (43%), Positives = 39/60 (65%)
Frame = -1
Query: 605 SAFKKRKLYEELLDKVPMLKALQPYERANLADALLPRTLVEGELIIRQGDTADGMYFVED 426
S +KRK+YEE L KV +L++L+ +ER +ADAL P +GE I+ QG+ D Y + +
Sbjct: 3 STLRKRKMYEEFLSKVSILESLEKWERLTVADALEPVQFEDGEKIVVQGEPGDDFYIITE 62
>BC051768-1|AAH51768.1| 1327|Homo sapiens patatin-like phospholipase
domain containing 6 protein.
Length = 1327
Score = 54.0 bits (124), Expect = 6e-07
Identities = 32/110 (29%), Positives = 56/110 (50%), Gaps = 1/110 (0%)
Frame = -1
Query: 512 DALLPRTLVE-GELIIRQGDTADGMYFVEDGSVSIRITRDDGNEHEIKRLGKGDYFGELA 336
D + T VE G + RQGD +D Y V +G + I R G + + G+GD G +
Sbjct: 594 DFAIDWTAVEAGRALYRQGDRSDCTYIVLNGRLRSVIQRGSGKKELVGEYGRGDLIGVVE 653
Query: 335 LVTHKPRAASVYAIGATKVAFLDVETFERLLGPCMEIMKRNIDXYEEQLV 186
+T +PRA +V+A+ T++A L T + +++ R I ++++
Sbjct: 654 ALTRQPRATTVHAVRDTELAKLPEGTLGHIKRRYPQVVTRLIHLLSQKIL 703
Score = 35.1 bits (77), Expect = 0.29
Identities = 32/133 (24%), Positives = 55/133 (41%), Gaps = 10/133 (7%)
Frame = -1
Query: 584 LYEELLDKVPMLKALQPYERA---NLADALLPRTLVEGELIIRQGDTADGMYFVEDGSVS 414
L E+L + ++ L +E+ L ++ + L +G+ + R G +Y V+DG +
Sbjct: 134 LPSEVLYMLKNVRVLGHFEKPLFLELCRHMVFQRLGQGDYVFRPGQPDASIYVVQDGLLE 193
Query: 413 IRITRDDGNEHEIKRLGKGDYFGELALV-------THKPRAASVYAIGATKVAFLDVETF 255
+ + DG E +K + GD L + H R S A + V L VE F
Sbjct: 194 LCLPGPDGKECVVKEVVPGDSVNSLLSILDVITGHQHPQRTVSARAARDSTVLRLPVEAF 253
Query: 254 ERLLGPCMEIMKR 216
+ E + R
Sbjct: 254 SAVFTKYPESLVR 266
>BC050553-1|AAH50553.1| 1327|Homo sapiens patatin-like phospholipase
domain containing 6 protein.
Length = 1327
Score = 54.0 bits (124), Expect = 6e-07
Identities = 32/110 (29%), Positives = 56/110 (50%), Gaps = 1/110 (0%)
Frame = -1
Query: 512 DALLPRTLVE-GELIIRQGDTADGMYFVEDGSVSIRITRDDGNEHEIKRLGKGDYFGELA 336
D + T VE G + RQGD +D Y V +G + I R G + + G+GD G +
Sbjct: 594 DFAIDWTAVEAGRALYRQGDRSDCTYIVLNGRLRSVIQRGSGKKELVGEYGRGDLIGVVE 653
Query: 335 LVTHKPRAASVYAIGATKVAFLDVETFERLLGPCMEIMKRNIDXYEEQLV 186
+T +PRA +V+A+ T++A L T + +++ R I ++++
Sbjct: 654 ALTRQPRATTVHAVRDTELAKLPEGTLGHIKRRYPQVVTRLIHLLSQKIL 703
Score = 35.1 bits (77), Expect = 0.29
Identities = 32/133 (24%), Positives = 55/133 (41%), Gaps = 10/133 (7%)
Frame = -1
Query: 584 LYEELLDKVPMLKALQPYERA---NLADALLPRTLVEGELIIRQGDTADGMYFVEDGSVS 414
L E+L + ++ L +E+ L ++ + L +G+ + R G +Y V+DG +
Sbjct: 134 LPSEVLYMLKNVRVLGHFEKPLFLELCRHMVFQRLGQGDYVFRPGQPDASIYVVQDGLLE 193
Query: 413 IRITRDDGNEHEIKRLGKGDYFGELALV-------THKPRAASVYAIGATKVAFLDVETF 255
+ + DG E +K + GD L + H R S A + V L VE F
Sbjct: 194 LCLPGPDGKECVVKEVVPGDSVNSLLSILDVITGHQHPQRTVSARAARDSTVLRLPVEAF 253
Query: 254 ERLLGPCMEIMKR 216
+ E + R
Sbjct: 254 SAVFTKYPESLVR 266
>AJ238850-1|CAB52754.1| 1203|Homo sapiens
hyperpolarization-activated channel type 4 protein.
Length = 1203
Score = 54.0 bits (124), Expect = 6e-07
Identities = 39/139 (28%), Positives = 67/139 (48%)
Frame = -1
Query: 575 ELLDKVPMLKALQPYERANLADALLPRTLVEGELIIRQGDTADGMYFVEDGSVSIRITRD 396
+L+ +P+ P ++ L G+ IIR+G MYF++ G VS+ +T+
Sbjct: 588 KLVASMPLFANADPNFVTSMLTKLRFEVFQPGDYIIREGTIGKKMYFIQHGVVSV-LTK- 645
Query: 395 DGNEHEIKRLGKGDYFGELALVTHKPRAASVYAIGATKVAFLDVETFERLLGPCMEIMKR 216
GN+ +L G YFGE+ L+T R ASV A ++ L V+ F +L +M+R
Sbjct: 646 -GNKET--KLADGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEE-YPMMRR 701
Query: 215 NIDXYEEQLVKLFGDKSNL 159
+ + G K+++
Sbjct: 702 AFETVALDRLDRIGKKNSI 720
>AJ132429-1|CAB42604.1| 1203|Homo sapiens
hyperpolarization-activated cyclic nucleotide gated
cation channel hHCN4 protein.
Length = 1203
Score = 54.0 bits (124), Expect = 6e-07
Identities = 39/139 (28%), Positives = 67/139 (48%)
Frame = -1
Query: 575 ELLDKVPMLKALQPYERANLADALLPRTLVEGELIIRQGDTADGMYFVEDGSVSIRITRD 396
+L+ +P+ P ++ L G+ IIR+G MYF++ G VS+ +T+
Sbjct: 588 KLVASMPLFANADPNFVTSMLTKLRFEVFQPGDYIIREGTIGKKMYFIQHGVVSV-LTK- 645
Query: 395 DGNEHEIKRLGKGDYFGELALVTHKPRAASVYAIGATKVAFLDVETFERLLGPCMEIMKR 216
GN+ +L G YFGE+ L+T R ASV A ++ L V+ F +L +M+R
Sbjct: 646 -GNKET--KLADGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEE-YPMMRR 701
Query: 215 NIDXYEEQLVKLFGDKSNL 159
+ + G K+++
Sbjct: 702 AFETVALDRLDRIGKKNSI 720
>AJ004832-1|CAA06164.1| 1327|Homo sapiens neuropathy target esterase
protein.
Length = 1327
Score = 54.0 bits (124), Expect = 6e-07
Identities = 32/110 (29%), Positives = 56/110 (50%), Gaps = 1/110 (0%)
Frame = -1
Query: 512 DALLPRTLVE-GELIIRQGDTADGMYFVEDGSVSIRITRDDGNEHEIKRLGKGDYFGELA 336
D + T VE G + RQGD +D Y V +G + I R G + + G+GD G +
Sbjct: 594 DFAIDWTAVEAGRALYRQGDRSDCTYIVLNGRLRSVIQRGSGKKELVGEYGRGDLIGVVE 653
Query: 335 LVTHKPRAASVYAIGATKVAFLDVETFERLLGPCMEIMKRNIDXYEEQLV 186
+T +PRA +V+A+ T++A L T + +++ R I ++++
Sbjct: 654 ALTRQPRATTVHAVRDTELAKLPEGTLGHIKRRYPQVVTRLIHLLSQKIL 703
Score = 35.1 bits (77), Expect = 0.29
Identities = 32/133 (24%), Positives = 55/133 (41%), Gaps = 10/133 (7%)
Frame = -1
Query: 584 LYEELLDKVPMLKALQPYERA---NLADALLPRTLVEGELIIRQGDTADGMYFVEDGSVS 414
L E+L + ++ L +E+ L ++ + L +G+ + R G +Y V+DG +
Sbjct: 134 LPSEVLYMLKNVRVLGHFEKPLFLELCRHMVFQRLGQGDYVFRPGQPDASIYVVQDGLLE 193
Query: 413 IRITRDDGNEHEIKRLGKGDYFGELALV-------THKPRAASVYAIGATKVAFLDVETF 255
+ + DG E +K + GD L + H R S A + V L VE F
Sbjct: 194 LCLPGPDGKECVVKEVVPGDSVNSLLSILDVITGHQHPQRTVSARAARDSTVLRLPVEAF 253
Query: 254 ERLLGPCMEIMKR 216
+ E + R
Sbjct: 254 SAVFTKYPESLVR 266
>AJ133727-1|CAB42630.1| 889|Homo sapiens
hyperpolarization-activated cyclic nucleotide-gated
channel hHCN2 protein.
Length = 889
Score = 53.2 bits (122), Expect = 1e-06
Identities = 41/139 (29%), Positives = 68/139 (48%)
Frame = -1
Query: 575 ELLDKVPMLKALQPYERANLADALLPRTLVEGELIIRQGDTADGMYFVEDGSVSIRITRD 396
+L+ +P+ P + L G+ IIR+G MYF++ G VS+ +T+
Sbjct: 537 KLVASMPLFANADPNFVTAMLTKLKFEVFQPGDYIIREGTIGKKMYFIQHGVVSV-LTK- 594
Query: 395 DGNEHEIKRLGKGDYFGELALVTHKPRAASVYAIGATKVAFLDVETFERLLGPCMEIMKR 216
GN+ E+K L G YFGE+ L+T R ASV A ++ L V+ F +L +M+R
Sbjct: 595 -GNK-EMK-LSDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEE-YPMMRR 650
Query: 215 NIDXYEEQLVKLFGDKSNL 159
+ + G K+++
Sbjct: 651 AFETVAIDRLDRIGKKNSI 669
>AJ012582-1|CAB42602.1| 889|Homo sapiens
hyperpolarization-activated cation channel HCN2 protein.
Length = 889
Score = 53.2 bits (122), Expect = 1e-06
Identities = 41/139 (29%), Positives = 68/139 (48%)
Frame = -1
Query: 575 ELLDKVPMLKALQPYERANLADALLPRTLVEGELIIRQGDTADGMYFVEDGSVSIRITRD 396
+L+ +P+ P + L G+ IIR+G MYF++ G VS+ +T+
Sbjct: 537 KLVASMPLFANADPNFVTAMLTKLKFEVFQPGDYIIREGTIGKKMYFIQHGVVSV-LTK- 594
Query: 395 DGNEHEIKRLGKGDYFGELALVTHKPRAASVYAIGATKVAFLDVETFERLLGPCMEIMKR 216
GN+ E+K L G YFGE+ L+T R ASV A ++ L V+ F +L +M+R
Sbjct: 595 -GNK-EMK-LSDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEE-YPMMRR 650
Query: 215 NIDXYEEQLVKLFGDKSNL 159
+ + G K+++
Sbjct: 651 AFETVAIDRLDRIGKKNSI 669
>AF065164-1|AAC28444.2| 889|Homo sapiens
hyperpolarization-activated, cyclic nucleotide-gated
channel 2 protein.
Length = 889
Score = 53.2 bits (122), Expect = 1e-06
Identities = 41/139 (29%), Positives = 68/139 (48%)
Frame = -1
Query: 575 ELLDKVPMLKALQPYERANLADALLPRTLVEGELIIRQGDTADGMYFVEDGSVSIRITRD 396
+L+ +P+ P + L G+ IIR+G MYF++ G VS+ +T+
Sbjct: 537 KLVASMPLFANADPNFVTAMLTKLKFEVFQPGDYIIREGTIGKKMYFIQHGVVSV-LTK- 594
Query: 395 DGNEHEIKRLGKGDYFGELALVTHKPRAASVYAIGATKVAFLDVETFERLLGPCMEIMKR 216
GN+ E+K L G YFGE+ L+T R ASV A ++ L V+ F +L +M+R
Sbjct: 595 -GNK-EMK-LSDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEE-YPMMRR 650
Query: 215 NIDXYEEQLVKLFGDKSNL 159
+ + G K+++
Sbjct: 651 AFETVAIDRLDRIGKKNSI 669
>AF064877-1|AAC39760.1| 597|Homo sapiens ion channel BCNG-2
protein.
Length = 597
Score = 53.2 bits (122), Expect = 1e-06
Identities = 41/139 (29%), Positives = 68/139 (48%)
Frame = -1
Query: 575 ELLDKVPMLKALQPYERANLADALLPRTLVEGELIIRQGDTADGMYFVEDGSVSIRITRD 396
+L+ +P+ P + L G+ IIR+G MYF++ G VS+ +T+
Sbjct: 391 KLVASMPLFANADPNFVTAMLTKLKFEVFQPGDYIIREGTIGKKMYFIQHGVVSV-LTK- 448
Query: 395 DGNEHEIKRLGKGDYFGELALVTHKPRAASVYAIGATKVAFLDVETFERLLGPCMEIMKR 216
GN+ E+K L G YFGE+ L+T R ASV A ++ L V+ F +L +M+R
Sbjct: 449 -GNK-EMK-LSDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEE-YPMMRR 504
Query: 215 NIDXYEEQLVKLFGDKSNL 159
+ + G K+++
Sbjct: 505 AFETVAIDRLDRIGKKNSI 523
>BC038229-1|AAH38229.1| 1332|Homo sapiens PNPLA6 protein protein.
Length = 1332
Score = 52.4 bits (120), Expect = 2e-06
Identities = 31/110 (28%), Positives = 55/110 (50%), Gaps = 1/110 (0%)
Frame = -1
Query: 512 DALLPRTLVE-GELIIRQGDTADGMYFVEDGSVSIRITRDDGNEHEIKRLGKGDYFGELA 336
D + T VE G + RQGD +D Y V +G + I R G + + G+GD G +
Sbjct: 600 DFAIDWTAVEAGRALYRQGDRSDCTYIVLNGRLRSVIQRGSGKKELVGEYGRGDLIGVVE 659
Query: 335 LVTHKPRAASVYAIGATKVAFLDVETFERLLGPCMEIMKRNIDXYEEQLV 186
+T +PRA +V+ + T++A L T + +++ R I ++++
Sbjct: 660 ALTRQPRATTVHTVRDTELAKLPEGTLGHIKRRYPQVVTRLIHLLSQKIL 709
Score = 35.1 bits (77), Expect = 0.29
Identities = 32/133 (24%), Positives = 55/133 (41%), Gaps = 10/133 (7%)
Frame = -1
Query: 584 LYEELLDKVPMLKALQPYERA---NLADALLPRTLVEGELIIRQGDTADGMYFVEDGSVS 414
L E+L + ++ L +E+ L ++ + L +G+ + R G +Y V+DG +
Sbjct: 140 LPSEVLYMLKNVRVLGHFEKPLFLELCRHMVFQRLGQGDYVFRPGQPDASIYVVQDGLLE 199
Query: 413 IRITRDDGNEHEIKRLGKGDYFGELALV-------THKPRAASVYAIGATKVAFLDVETF 255
+ + DG E +K + GD L + H R S A + V L VE F
Sbjct: 200 LCLPGPDGKECVVKEVVPGDSVNSLLSILDVITGHQHPQRTVSARAARDSTVLRLPVEAF 259
Query: 254 ERLLGPCMEIMKR 216
+ E + R
Sbjct: 260 SAVFTKYPESLVR 272
>AL365502-7|CAI14582.1| 1317|Homo sapiens patatin-like phospholipase
domain containing 7 protein.
Length = 1317
Score = 51.6 bits (118), Expect = 3e-06
Identities = 28/99 (28%), Positives = 50/99 (50%)
Frame = -1
Query: 482 GELIIRQGDTADGMYFVEDGSVSIRITRDDGNEHEIKRLGKGDYFGELALVTHKPRAASV 303
G I RQGD +D Y + G + I +DDG + G+GD G + +TH+ RA +V
Sbjct: 600 GRAIYRQGDKSDCTYIMLSGRLRSVIRKDDGKKRLAGEYGRGDLVGVVETLTHQARATTV 659
Query: 302 YAIGATKVAFLDVETFERLLGPCMEIMKRNIDXYEEQLV 186
+A+ +++A L + +++ R I E+++
Sbjct: 660 HAVRDSELAKLPAGALTSIKRRYPQVVTRLIHLLGEKIL 698
>AL365502-6|CAI14581.1| 1281|Homo sapiens patatin-like phospholipase
domain containing 7 protein.
Length = 1281
Score = 51.6 bits (118), Expect = 3e-06
Identities = 28/99 (28%), Positives = 50/99 (50%)
Frame = -1
Query: 482 GELIIRQGDTADGMYFVEDGSVSIRITRDDGNEHEIKRLGKGDYFGELALVTHKPRAASV 303
G I RQGD +D Y + G + I +DDG + G+GD G + +TH+ RA +V
Sbjct: 591 GRAIYRQGDKSDCTYIMLSGRLRSVIRKDDGKKRLAGEYGRGDLVGVVETLTHQARATTV 650
Query: 302 YAIGATKVAFLDVETFERLLGPCMEIMKRNIDXYEEQLV 186
+A+ +++A L + +++ R I E+++
Sbjct: 651 HAVRDSELAKLPAGALTSIKRRYPQVVTRLIHLLGEKIL 689
>AL365502-5|CAI14579.1| 923|Homo sapiens patatin-like phospholipase
domain containing 7 protein.
Length = 923
Score = 51.6 bits (118), Expect = 3e-06
Identities = 28/99 (28%), Positives = 50/99 (50%)
Frame = -1
Query: 482 GELIIRQGDTADGMYFVEDGSVSIRITRDDGNEHEIKRLGKGDYFGELALVTHKPRAASV 303
G I RQGD +D Y + G + I +DDG + G+GD G + +TH+ RA +V
Sbjct: 206 GRAIYRQGDKSDCTYIMLSGRLRSVIRKDDGKKRLAGEYGRGDLVGVVETLTHQARATTV 265
Query: 302 YAIGATKVAFLDVETFERLLGPCMEIMKRNIDXYEEQLV 186
+A+ +++A L + +++ R I E+++
Sbjct: 266 HAVRDSELAKLPAGALTSIKRRYPQVVTRLIHLLGEKIL 304
>AK125060-1|BAC86036.1| 1317|Homo sapiens protein ( Homo sapiens
cDNA FLJ43070 fis, clone BRTHA3009090, moderately
similar to Homo sapiens neuropathy target esterase
(NTE). ).
Length = 1317
Score = 51.6 bits (118), Expect = 3e-06
Identities = 28/99 (28%), Positives = 50/99 (50%)
Frame = -1
Query: 482 GELIIRQGDTADGMYFVEDGSVSIRITRDDGNEHEIKRLGKGDYFGELALVTHKPRAASV 303
G I RQGD +D Y + G + I +DDG + G+GD G + +TH+ RA +V
Sbjct: 600 GRAIYRQGDKSDCTYIMLSGRLRSVIRKDDGKKRLAGEYGRGDLVGVVETLTHQARATTV 659
Query: 302 YAIGATKVAFLDVETFERLLGPCMEIMKRNIDXYEEQLV 186
+A+ +++A L + +++ R I E+++
Sbjct: 660 HAVRDSELAKLPAGALTSIKRRYPQVVTRLIHLLGEKIL 698
>BC028024-1|AAH28024.2| 450|Homo sapiens HCN3 protein protein.
Length = 450
Score = 48.8 bits (111), Expect = 2e-05
Identities = 34/110 (30%), Positives = 55/110 (50%), Gaps = 2/110 (1%)
Frame = -1
Query: 482 GELIIRQGDTADGMYFVEDGSVSI--RITRDDGNEHEIKRLGKGDYFGELALVTHKPRAA 309
G+L++R+G MYF++ G +S+ R RD RL G YFGE+ L+T R A
Sbjct: 128 GDLVVREGSVGRKMYFIQHGLLSVLARGARDT-------RLTDGSYFGEICLLTRGRRTA 180
Query: 308 SVYAIGATKVAFLDVETFERLLGPCMEIMKRNIDXYEEQLVKLFGDKSNL 159
SV A ++ L V+ F +L +M+R + + G K+++
Sbjct: 181 SVRADTYCRLYSLSVDHFNAVLEE-FPMMRRAFETVAMDRLLRIGKKNSI 229
>BC000066-1|AAH00066.1| 571|Homo sapiens Unknown (protein for
IMAGE:3507934) protein.
Length = 571
Score = 48.8 bits (111), Expect = 2e-05
Identities = 34/110 (30%), Positives = 55/110 (50%), Gaps = 2/110 (1%)
Frame = -1
Query: 482 GELIIRQGDTADGMYFVEDGSVSI--RITRDDGNEHEIKRLGKGDYFGELALVTHKPRAA 309
G+L++R+G MYF++ G +S+ R RD RL G YFGE+ L+T R A
Sbjct: 249 GDLVVREGSVGRKMYFIQHGLLSVLARGARDT-------RLTDGSYFGEICLLTRGRRTA 301
Query: 308 SVYAIGATKVAFLDVETFERLLGPCMEIMKRNIDXYEEQLVKLFGDKSNL 159
SV A ++ L V+ F +L +M+R + + G K+++
Sbjct: 302 SVRADTYCRLYSLSVDHFNAVLEE-FPMMRRAFETVAMDRLLRIGKKNSI 350
>AL713999-31|CAI95100.1| 774|Homo sapiens hyperpolarization
activated cyclic nucleotide-gated potassium channel 3
protein.
Length = 774
Score = 48.8 bits (111), Expect = 2e-05
Identities = 34/110 (30%), Positives = 55/110 (50%), Gaps = 2/110 (1%)
Frame = -1
Query: 482 GELIIRQGDTADGMYFVEDGSVSI--RITRDDGNEHEIKRLGKGDYFGELALVTHKPRAA 309
G+L++R+G MYF++ G +S+ R RD RL G YFGE+ L+T R A
Sbjct: 452 GDLVVREGSVGRKMYFIQHGLLSVLARGARDT-------RLTDGSYFGEICLLTRGRRTA 504
Query: 308 SVYAIGATKVAFLDVETFERLLGPCMEIMKRNIDXYEEQLVKLFGDKSNL 159
SV A ++ L V+ F +L +M+R + + G K+++
Sbjct: 505 SVRADTYCRLYSLSVDHFNAVLEE-FPMMRRAFETVAMDRLLRIGKKNSI 553
>AF488550-1|AAO49470.1| 774|Homo sapiens hyperpolarization
activated cyclic nucleotide-gated potassium channel
protein.
Length = 774
Score = 48.8 bits (111), Expect = 2e-05
Identities = 34/110 (30%), Positives = 55/110 (50%), Gaps = 2/110 (1%)
Frame = -1
Query: 482 GELIIRQGDTADGMYFVEDGSVSI--RITRDDGNEHEIKRLGKGDYFGELALVTHKPRAA 309
G+L++R+G MYF++ G +S+ R RD RL G YFGE+ L+T R A
Sbjct: 452 GDLVVREGSVGRKMYFIQHGLLSVLARGARDT-------RLTDGSYFGEICLLTRGRRTA 504
Query: 308 SVYAIGATKVAFLDVETFERLLGPCMEIMKRNIDXYEEQLVKLFGDKSNL 159
SV A ++ L V+ F +L +M+R + + G K+++
Sbjct: 505 SVRADTYCRLYSLSVDHFNAVLEE-FPMMRRAFETVAMDRLLRIGKKNSI 553
>AB040968-1|BAA96059.2| 711|Homo sapiens KIAA1535 protein protein.
Length = 711
Score = 48.8 bits (111), Expect = 2e-05
Identities = 34/110 (30%), Positives = 55/110 (50%), Gaps = 2/110 (1%)
Frame = -1
Query: 482 GELIIRQGDTADGMYFVEDGSVSI--RITRDDGNEHEIKRLGKGDYFGELALVTHKPRAA 309
G+L++R+G MYF++ G +S+ R RD RL G YFGE+ L+T R A
Sbjct: 389 GDLVVREGSVGRKMYFIQHGLLSVLARGARDT-------RLTDGSYFGEICLLTRGRRTA 441
Query: 308 SVYAIGATKVAFLDVETFERLLGPCMEIMKRNIDXYEEQLVKLFGDKSNL 159
SV A ++ L V+ F +L +M+R + + G K+++
Sbjct: 442 SVRADTYCRLYSLSVDHFNAVLEE-FPMMRRAFETVAMDRLLRIGKKNSI 490
>AF064876-1|AAC39759.1| 749|Homo sapiens ion channel BCNG-1
protein.
Length = 749
Score = 48.0 bits (109), Expect = 4e-05
Identities = 38/139 (27%), Positives = 64/139 (46%)
Frame = -1
Query: 575 ELLDKVPMLKALQPYERANLADALLPRTLVEGELIIRQGDTADGMYFVEDGSVSIRITRD 396
+L+ +P+ P + L G+ IIR+G MYF++ G + IT+
Sbjct: 347 KLVATMPLFANADPNFVTAMLSKLRFEVFQPGDYIIREGAVGKKMYFIQHGVAGV-ITK- 404
Query: 395 DGNEHEIKRLGKGDYFGELALVTHKPRAASVYAIGATKVAFLDVETFERLLGPCMEIMKR 216
+ E+K L G YFGE+ L+T R ASV A ++ L V+ F +L +M+R
Sbjct: 405 --SSKEMK-LTDGSYFGEICLLTKGRRTASVRADTYCRLYSLSVDNFNEVLEE-YPMMRR 460
Query: 215 NIDXYEEQLVKLFGDKSNL 159
+ + G K+++
Sbjct: 461 AFETVAIDRLDRIGKKNSI 479
>U78516-1|AAD03422.1| 1011|Homo sapiens cAMP-regulated guanine
nucleotide exchange factor II protein.
Length = 1011
Score = 47.2 bits (107), Expect = 7e-05
Identities = 39/117 (33%), Positives = 58/117 (49%), Gaps = 3/117 (2%)
Frame = -1
Query: 584 LYEELLDKVPMLKALQPYERANLADALLPRTLVEGELII-RQGDTADGMYFVEDGSVSIR 408
+YEELL + L L + LA L+ + +G ++ QG+ Y + GSV++
Sbjct: 347 IYEELLH-IKALSHLSTTVKRELAGVLIFESHAKGGTVLFNQGEEGTSWYIILKGSVNVV 405
Query: 407 ITRDDGNEHEIKRLGKGDYFGELALVTHKPRAASVYAIGATKVAFL--DVETFERLL 243
I + + L +GD FG+LALV PRAAS+ + FL D E F R+L
Sbjct: 406 IY----GKGVVCTLHEGDDFGKLALVNDAPRAASI-VLREDNCHFLRVDKEDFNRIL 457
>BC040183-1|AAH40183.1| 867|Homo sapiens RAPGEF4 protein protein.
Length = 867
Score = 47.2 bits (107), Expect = 7e-05
Identities = 39/117 (33%), Positives = 58/117 (49%), Gaps = 3/117 (2%)
Frame = -1
Query: 584 LYEELLDKVPMLKALQPYERANLADALLPRTLVEGELII-RQGDTADGMYFVEDGSVSIR 408
+YEELL + L L + LA L+ + +G ++ QG+ Y + GSV++
Sbjct: 203 IYEELLH-IKALSHLSTTVKRELAGVLIFESHAKGGTVLFNQGEEGTSWYIILKGSVNVV 261
Query: 407 ITRDDGNEHEIKRLGKGDYFGELALVTHKPRAASVYAIGATKVAFL--DVETFERLL 243
I + + L +GD FG+LALV PRAAS+ + FL D E F R+L
Sbjct: 262 IY----GKGVVCTLHEGDDFGKLALVNDAPRAASI-VLREDNCHFLRVDKEDFNRIL 313
>BC024004-1|AAH24004.1| 1011|Homo sapiens Rap guanine nucleotide
exchange factor (GEF) 4 protein.
Length = 1011
Score = 47.2 bits (107), Expect = 7e-05
Identities = 39/117 (33%), Positives = 58/117 (49%), Gaps = 3/117 (2%)
Frame = -1
Query: 584 LYEELLDKVPMLKALQPYERANLADALLPRTLVEGELII-RQGDTADGMYFVEDGSVSIR 408
+YEELL + L L + LA L+ + +G ++ QG+ Y + GSV++
Sbjct: 347 IYEELLH-IKALSHLSTTVKRELAGVLIFESHAKGGTVLFNQGEEGTSWYIILKGSVNVV 405
Query: 407 ITRDDGNEHEIKRLGKGDYFGELALVTHKPRAASVYAIGATKVAFL--DVETFERLL 243
I + + L +GD FG+LALV PRAAS+ + FL D E F R+L
Sbjct: 406 IY----GKGVVCTLHEGDDFGKLALVNDAPRAASI-VLREDNCHFLRVDKEDFNRIL 457
>AB027471-1|BAB72179.1| 1011|Homo sapiens cAMP-GEFII protein.
Length = 1011
Score = 47.2 bits (107), Expect = 7e-05
Identities = 39/117 (33%), Positives = 58/117 (49%), Gaps = 3/117 (2%)
Frame = -1
Query: 584 LYEELLDKVPMLKALQPYERANLADALLPRTLVEGELII-RQGDTADGMYFVEDGSVSIR 408
+YEELL + L L + LA L+ + +G ++ QG+ Y + GSV++
Sbjct: 347 IYEELLH-IKALSHLSTTVKRELAGVLIFESHAKGGTVLFNQGEEGTSWYIILKGSVNVV 405
Query: 407 ITRDDGNEHEIKRLGKGDYFGELALVTHKPRAASVYAIGATKVAFL--DVETFERLL 243
I + + L +GD FG+LALV PRAAS+ + FL D E F R+L
Sbjct: 406 IY----GKGVVCTLHEGDDFGKLALVNDAPRAASI-VLREDNCHFLRVDKEDFNRIL 457
>AF488549-1|AAO49469.1| 890|Homo sapiens hyperpolarization
activated cyclic nucleotide-gated potassium channel
protein.
Length = 890
Score = 45.2 bits (102), Expect = 3e-04
Identities = 32/110 (29%), Positives = 52/110 (47%)
Frame = -1
Query: 575 ELLDKVPMLKALQPYERANLADALLPRTLVEGELIIRQGDTADGMYFVEDGSVSIRITRD 396
+L+ +P+ P + L G+ I+R+G MYF++ G + IT+
Sbjct: 468 KLVATMPLFANADPNFVTAMLSKLRFEVFQPGDYIVREGAVGKKMYFIQHGVAGV-ITK- 525
Query: 395 DGNEHEIKRLGKGDYFGELALVTHKPRAASVYAIGATKVAFLDVETFERL 246
+ E+K L G YFGE+ L+T R ASV A ++ L V+ F +
Sbjct: 526 --SSKEMK-LTDGSYFGEICLLTKGRRTASVRADTYCRLYSLSVDNFNEV 572
>U78169-1|AAD02890.1| 556|Homo sapiens cAMP-regulated guanine
nucleotide exchange factor I protein.
Length = 556
Score = 43.6 bits (98), Expect = 8e-04
Identities = 30/94 (31%), Positives = 45/94 (47%)
Frame = -1
Query: 584 LYEELLDKVPMLKALQPYERANLADALLPRTLVEGELIIRQGDTADGMYFVEDGSVSIRI 405
++EELL + +R A L G ++ QGD Y + GSV++ +
Sbjct: 194 IFEELLHIKAVAHLSNSVKRELAAVLLFEPHSKAGTVLFSQGDKGTSWYIIWKGSVNV-V 252
Query: 404 TRDDGNEHEIKRLGKGDYFGELALVTHKPRAASV 303
T G + L +GD FG+LALV PRAA++
Sbjct: 253 THGKGL---VTTLHEGDDFGQLALVNDAPRAATI 283
>U78168-1|AAD12740.1| 881|Homo sapiens cAMP-regulated guanine
nucleotide exchange factor I protein.
Length = 881
Score = 43.6 bits (98), Expect = 8e-04
Identities = 30/94 (31%), Positives = 45/94 (47%)
Frame = -1
Query: 584 LYEELLDKVPMLKALQPYERANLADALLPRTLVEGELIIRQGDTADGMYFVEDGSVSIRI 405
++EELL + +R A L G ++ QGD Y + GSV++ +
Sbjct: 194 IFEELLHIKAVAHLSNSVKRELAAVLLFEPHSKAGTVLFSQGDKGTSWYIIWKGSVNV-V 252
Query: 404 TRDDGNEHEIKRLGKGDYFGELALVTHKPRAASV 303
T G + L +GD FG+LALV PRAA++
Sbjct: 253 THGKGL---VTTLHEGDDFGQLALVNDAPRAATI 283
>BC092404-1|AAH92404.1| 881|Homo sapiens Rap guanine nucleotide
exchange factor (GEF) 3 protein.
Length = 881
Score = 43.6 bits (98), Expect = 8e-04
Identities = 30/94 (31%), Positives = 45/94 (47%)
Frame = -1
Query: 584 LYEELLDKVPMLKALQPYERANLADALLPRTLVEGELIIRQGDTADGMYFVEDGSVSIRI 405
++EELL + +R A L G ++ QGD Y + GSV++ +
Sbjct: 194 IFEELLHIKAVAHLSNSVKRELAAVLLFEPHSKAGTVLFSQGDKGTSWYIIWKGSVNV-V 252
Query: 404 TRDDGNEHEIKRLGKGDYFGELALVTHKPRAASV 303
T G + L +GD FG+LALV PRAA++
Sbjct: 253 THGKGL---VTTLHEGDDFGQLALVNDAPRAATI 283
>BC068477-1|AAH68477.1| 343|Homo sapiens RAPGEF3 protein protein.
Length = 343
Score = 43.6 bits (98), Expect = 8e-04
Identities = 30/94 (31%), Positives = 45/94 (47%)
Frame = -1
Query: 584 LYEELLDKVPMLKALQPYERANLADALLPRTLVEGELIIRQGDTADGMYFVEDGSVSIRI 405
++EELL + +R A L G ++ QGD Y + GSV++ +
Sbjct: 194 IFEELLHIKAVAHLSNSVKRELAAVLLFEPHSKAGTVLFSQGDKGTSWYIIWKGSVNV-V 252
Query: 404 TRDDGNEHEIKRLGKGDYFGELALVTHKPRAASV 303
T G + L +GD FG+LALV PRAA++
Sbjct: 253 THGKGL---VTTLHEGDDFGQLALVNDAPRAATI 283
>BC040534-1|AAH40534.1| 321|Homo sapiens RAPGEF3 protein protein.
Length = 321
Score = 43.6 bits (98), Expect = 8e-04
Identities = 30/94 (31%), Positives = 45/94 (47%)
Frame = -1
Query: 584 LYEELLDKVPMLKALQPYERANLADALLPRTLVEGELIIRQGDTADGMYFVEDGSVSIRI 405
++EELL + +R A L G ++ QGD Y + GSV++ +
Sbjct: 194 IFEELLHIKAVAHLSNSVKRELAAVLLFEPHSKAGTVLFSQGDKGTSWYIIWKGSVNV-V 252
Query: 404 TRDDGNEHEIKRLGKGDYFGELALVTHKPRAASV 303
T G + L +GD FG+LALV PRAA++
Sbjct: 253 THGKGL---VTTLHEGDDFGQLALVNDAPRAATI 283
>BC017728-1|AAH17728.1| 881|Homo sapiens Rap guanine nucleotide
exchange factor (GEF) 3 protein.
Length = 881
Score = 43.6 bits (98), Expect = 8e-04
Identities = 30/94 (31%), Positives = 45/94 (47%)
Frame = -1
Query: 584 LYEELLDKVPMLKALQPYERANLADALLPRTLVEGELIIRQGDTADGMYFVEDGSVSIRI 405
++EELL + +R A L G ++ QGD Y + GSV++ +
Sbjct: 194 IFEELLHIKAVAHLSNSVKRELAAVLLFEPHSKAGTVLFSQGDKGTSWYIIWKGSVNV-V 252
Query: 404 TRDDGNEHEIKRLGKGDYFGELALVTHKPRAASV 303
T G + L +GD FG+LALV PRAA++
Sbjct: 253 THGKGL---VTTLHEGDDFGQLALVNDAPRAATI 283
>AF103905-1|AAC83381.1| 881|Homo sapiens Rap1 guanine-nucleotide
exchange factor protein.
Length = 881
Score = 43.6 bits (98), Expect = 8e-04
Identities = 30/94 (31%), Positives = 45/94 (47%)
Frame = -1
Query: 584 LYEELLDKVPMLKALQPYERANLADALLPRTLVEGELIIRQGDTADGMYFVEDGSVSIRI 405
++EELL + +R A L G ++ QGD Y + GSV++ +
Sbjct: 194 IFEELLHIKAVAHLSNSVKRELAAVLLFEPHSKAGTVLFSQGDKGTSWYIIWKGSVNV-V 252
Query: 404 TRDDGNEHEIKRLGKGDYFGELALVTHKPRAASV 303
T G + L +GD FG+LALV PRAA++
Sbjct: 253 THGKGL---VTTLHEGDDFGQLALVNDAPRAATI 283
>BC040277-1|AAH40277.1| 474|Homo sapiens CNGA4 protein protein.
Length = 474
Score = 43.2 bits (97), Expect = 0.001
Identities = 22/62 (35%), Positives = 35/62 (56%)
Frame = -1
Query: 506 LLPRTLVEGELIIRQGDTADGMYFVEDGSVSIRITRDDGNEHEIKRLGKGDYFGELALVT 327
L P+T GE + R+GD MY + +G ++ + DDG + LG G YFGE++++
Sbjct: 382 LQPQTYSPGEYVCRKGDIGQEMYIIREGQLA--VVADDGIT-QYAVLGAGLYFGEISIIN 438
Query: 326 HK 321
K
Sbjct: 439 IK 440
>S76069-1|AAD14208.1| 261|Homo sapiens CNG3 protein.
Length = 261
Score = 42.7 bits (96), Expect = 0.001
Identities = 32/116 (27%), Positives = 54/116 (46%), Gaps = 6/116 (5%)
Frame = -1
Query: 650 LWAMDRHTFRRILLKSAFKKRKLYEEL---LDKVPMLKALQPYERANLADALL---PRTL 489
LWA + + +LKS K K + LD + ++ Q E L + +L P
Sbjct: 125 LWANKKTVDEKEVLKSLPDKLKAEIAINVHLDTLKKVRIFQDCEAGLLVELVLKLRPTVF 184
Query: 488 VEGELIIRQGDTADGMYFVEDGSVSIRITRDDGNEHEIKRLGKGDYFGELALVTHK 321
G+ I ++GD MY + +G ++ + DDG + L G YFGE++++ K
Sbjct: 185 SPGDYICKKGDIGKEMYIINEGKLA--VVADDGVTQFVV-LSDGSYFGEISILNIK 237
>BC096300-1|AAH96300.1| 694|Homo sapiens cyclic nucleotide gated
channel alpha 3 protein.
Length = 694
Score = 42.7 bits (96), Expect = 0.001
Identities = 32/116 (27%), Positives = 54/116 (46%), Gaps = 6/116 (5%)
Frame = -1
Query: 650 LWAMDRHTFRRILLKSAFKKRKLYEEL---LDKVPMLKALQPYERANLADALL---PRTL 489
LWA + + +LKS K K + LD + ++ Q E L + +L P
Sbjct: 444 LWANKKTVDEKEVLKSLPDKLKAEIAINVHLDTLKKVRIFQDCEAGLLVELVLKLRPTVF 503
Query: 488 VEGELIIRQGDTADGMYFVEDGSVSIRITRDDGNEHEIKRLGKGDYFGELALVTHK 321
G+ I ++GD MY + +G ++ + DDG + L G YFGE++++ K
Sbjct: 504 SPGDYICKKGDIGKEMYIINEGKLA--VVADDGVTQFVV-LSDGSYFGEISILNIK 556
>BC096299-1|AAH96299.1| 676|Homo sapiens cyclic nucleotide gated
channel alpha 3 protein.
Length = 676
Score = 42.7 bits (96), Expect = 0.001
Identities = 32/116 (27%), Positives = 54/116 (46%), Gaps = 6/116 (5%)
Frame = -1
Query: 650 LWAMDRHTFRRILLKSAFKKRKLYEEL---LDKVPMLKALQPYERANLADALL---PRTL 489
LWA + + +LKS K K + LD + ++ Q E L + +L P
Sbjct: 426 LWANKKTVDEKEVLKSLPDKLKAEIAINVHLDTLKKVRIFQDCEAGLLVELVLKLRPTVF 485
Query: 488 VEGELIIRQGDTADGMYFVEDGSVSIRITRDDGNEHEIKRLGKGDYFGELALVTHK 321
G+ I ++GD MY + +G ++ + DDG + L G YFGE++++ K
Sbjct: 486 SPGDYICKKGDIGKEMYIINEGKLA--VVADDGVTQFVV-LSDGSYFGEISILNIK 538
>BC096298-1|AAH96298.1| 694|Homo sapiens cyclic nucleotide gated
channel alpha 3 protein.
Length = 694
Score = 42.7 bits (96), Expect = 0.001
Identities = 32/116 (27%), Positives = 54/116 (46%), Gaps = 6/116 (5%)
Frame = -1
Query: 650 LWAMDRHTFRRILLKSAFKKRKLYEEL---LDKVPMLKALQPYERANLADALL---PRTL 489
LWA + + +LKS K K + LD + ++ Q E L + +L P
Sbjct: 444 LWANKKTVDEKEVLKSLPDKLKAEIAINVHLDTLKKVRIFQDCEAGLLVELVLKLRPTVF 503
Query: 488 VEGELIIRQGDTADGMYFVEDGSVSIRITRDDGNEHEIKRLGKGDYFGELALVTHK 321
G+ I ++GD MY + +G ++ + DDG + L G YFGE++++ K
Sbjct: 504 SPGDYICKKGDIGKEMYIINEGKLA--VVADDGVTQFVV-LSDGSYFGEISILNIK 556
>AK131300-1|BAD18468.1| 698|Homo sapiens mRNA. protein.
Length = 698
Score = 42.7 bits (96), Expect = 0.001
Identities = 32/116 (27%), Positives = 54/116 (46%), Gaps = 6/116 (5%)
Frame = -1
Query: 650 LWAMDRHTFRRILLKSAFKKRKLYEEL---LDKVPMLKALQPYERANLADALL---PRTL 489
LWA + + +LKS K K + LD + ++ Q E L + +L P
Sbjct: 448 LWANKKTVDEKEVLKSLPDKLKAEIAINVHLDTLKKVRIFQDCEAGLLVELVLKLRPTVF 507
Query: 488 VEGELIIRQGDTADGMYFVEDGSVSIRITRDDGNEHEIKRLGKGDYFGELALVTHK 321
G+ I ++GD MY + +G ++ + DDG + L G YFGE++++ K
Sbjct: 508 SPGDYICKKGDIGKEMYIINEGKLA--VVADDGVTQFVV-LSDGSYFGEISILNIK 560
>AF065314-1|AAC17440.1| 694|Homo sapiens cone photoreceptor
cGMP-gated channel alpha subunit protein.
Length = 694
Score = 42.7 bits (96), Expect = 0.001
Identities = 32/116 (27%), Positives = 54/116 (46%), Gaps = 6/116 (5%)
Frame = -1
Query: 650 LWAMDRHTFRRILLKSAFKKRKLYEEL---LDKVPMLKALQPYERANLADALL---PRTL 489
LWA + + +LKS K K + LD + ++ Q E L + +L P
Sbjct: 444 LWANKKTVDEKEVLKSLPDKLKAEIAINVHLDTLKKVRIFQDCEAGLLVELVLKLRPTVF 503
Query: 488 VEGELIIRQGDTADGMYFVEDGSVSIRITRDDGNEHEIKRLGKGDYFGELALVTHK 321
G+ I ++GD MY + +G ++ + DDG + L G YFGE++++ K
Sbjct: 504 SPGDYICKKGDIGKEMYIINEGKLA--VVADDGVTQFVV-LSDGSYFGEISILNIK 556
>AC092675-2|AAY24181.1| 694|Homo sapiens unknown protein.
Length = 694
Score = 42.7 bits (96), Expect = 0.001
Identities = 32/116 (27%), Positives = 54/116 (46%), Gaps = 6/116 (5%)
Frame = -1
Query: 650 LWAMDRHTFRRILLKSAFKKRKLYEEL---LDKVPMLKALQPYERANLADALL---PRTL 489
LWA + + +LKS K K + LD + ++ Q E L + +L P
Sbjct: 444 LWANKKTVDEKEVLKSLPDKLKAEIAINVHLDTLKKVRIFQDCEAGLLVELVLKLRPTVF 503
Query: 488 VEGELIIRQGDTADGMYFVEDGSVSIRITRDDGNEHEIKRLGKGDYFGELALVTHK 321
G+ I ++GD MY + +G ++ + DDG + L G YFGE++++ K
Sbjct: 504 SPGDYICKKGDIGKEMYIINEGKLA--VVADDGVTQFVV-LSDGSYFGEISILNIK 556
>AB209681-1|BAD92918.1| 643|Homo sapiens RAP
guanine-nucleotide-exchange factor 4 variant protein.
Length = 643
Score = 40.7 bits (91), Expect = 0.006
Identities = 29/80 (36%), Positives = 41/80 (51%), Gaps = 2/80 (2%)
Frame = -1
Query: 476 LIIRQGDTADGMYFVEDGSVSIRITRDDGNEHEIKRLGKGDYFGELALVTHKPRAASVYA 297
L+ QG+ Y + GSV++ I + + L +GD FG+LALV PRAAS+
Sbjct: 15 LVFNQGEEGTSWYIILKGSVNVVIY----GKGVVCTLHEGDDFGKLALVNDAPRAASI-V 69
Query: 296 IGATKVAFL--DVETFERLL 243
+ FL D E F R+L
Sbjct: 70 LREDNCHFLRVDKEDFNRIL 89
>S76062-1|AAD14206.1| 261|Homo sapiens CNG1 protein.
Length = 261
Score = 37.5 bits (83), Expect = 0.054
Identities = 19/62 (30%), Positives = 34/62 (54%)
Frame = -1
Query: 506 LLPRTLVEGELIIRQGDTADGMYFVEDGSVSIRITRDDGNEHEIKRLGKGDYFGELALVT 327
L P+ G+ I ++GD MY +++G ++ + DDG + L G YFGE++++
Sbjct: 179 LQPQVYSPGDYICKKGDIGREMYIIKEGKLA--VVADDGVTQFVV-LSDGSYFGEISILN 235
Query: 326 HK 321
K
Sbjct: 236 IK 237
>S42457-1|AAB22778.1| 686|Homo sapiens rod photoreceptor cGMP-gated
channel protein.
Length = 686
Score = 37.5 bits (83), Expect = 0.054
Identities = 19/62 (30%), Positives = 34/62 (54%)
Frame = -1
Query: 506 LLPRTLVEGELIIRQGDTADGMYFVEDGSVSIRITRDDGNEHEIKRLGKGDYFGELALVT 327
L P+ G+ I ++GD MY +++G ++ + DDG + L G YFGE++++
Sbjct: 491 LQPQVYSPGDYICKKGDIGREMYIIKEGKLA--VVADDGVTQFVV-LSDGSYFGEISILN 547
Query: 326 HK 321
K
Sbjct: 548 IK 549
>AC107068-3|AAY40919.1| 690|Homo sapiens unknown protein.
Length = 690
Score = 37.5 bits (83), Expect = 0.054
Identities = 19/62 (30%), Positives = 34/62 (54%)
Frame = -1
Query: 506 LLPRTLVEGELIIRQGDTADGMYFVEDGSVSIRITRDDGNEHEIKRLGKGDYFGELALVT 327
L P+ G+ I ++GD MY +++G ++ + DDG + L G YFGE++++
Sbjct: 495 LQPQVYSPGDYICKKGDIGREMYIIKEGKLA--VVADDGVTQFVV-LSDGSYFGEISILN 551
Query: 326 HK 321
K
Sbjct: 552 IK 553
>AK055880-1|BAB71033.1| 702|Homo sapiens protein ( Homo sapiens
cDNA FLJ31318 fis, clone LIVER1000433, moderately
similar to Homo sapiens mRNA for neuropathy target
esterase. ).
Length = 702
Score = 36.7 bits (81), Expect = 0.094
Identities = 19/74 (25%), Positives = 38/74 (51%)
Frame = -1
Query: 407 ITRDDGNEHEIKRLGKGDYFGELALVTHKPRAASVYAIGATKVAFLDVETFERLLGPCME 228
I +DDG + G+GD G + +TH+ RA +V+A+ +++A L + +
Sbjct: 10 IRKDDGKKRLAGEYGRGDLVGVVETLTHQARATTVHAVRDSELAKLPAGALTSIKRRYPQ 69
Query: 227 IMKRNIDXYEEQLV 186
++ R I E+++
Sbjct: 70 VVTRLIHLLGEKIL 83
>AB033108-1|BAA86596.1| 1117|Homo sapiens KIAA1282 protein protein.
Length = 1117
Score = 36.7 bits (81), Expect = 0.094
Identities = 28/80 (35%), Positives = 40/80 (50%)
Frame = -1
Query: 584 LYEELLDKVPMLKALQPYERANLADALLPRTLVEGELIIRQGDTADGMYFVEDGSVSIRI 405
L++E+L ++P+ +A L+ AL P GE +I QGD +YFV GS+ +
Sbjct: 607 LHKEVL-QLPLFEAASRGCLRALSLALRPAFCTPGEYLIHQGDALQALYFVCSGSMEV-- 663
Query: 404 TRDDGNEHEIKRLGKGDYFG 345
G I LGKGD G
Sbjct: 664 -LKGGTVLAI--LGKGDLIG 680
>AB022696-1|BAA83590.1| 1083|Homo sapiens BEC1 protein.
Length = 1083
Score = 36.7 bits (81), Expect = 0.094
Identities = 28/80 (35%), Positives = 40/80 (50%)
Frame = -1
Query: 584 LYEELLDKVPMLKALQPYERANLADALLPRTLVEGELIIRQGDTADGMYFVEDGSVSIRI 405
L++E+L ++P+ +A L+ AL P GE +I QGD +YFV GS+ +
Sbjct: 573 LHKEVL-QLPLFEAASRGCLRALSLALRPAFCTPGEYLIHQGDALQALYFVCSGSMEV-- 629
Query: 404 TRDDGNEHEIKRLGKGDYFG 345
G I LGKGD G
Sbjct: 630 -LKGGTVLAI--LGKGDLIG 646
>AF032897-1|AAD01946.1| 1196|Homo sapiens potassium channel subunit
protein.
Length = 1196
Score = 36.3 bits (80), Expect = 0.12
Identities = 18/57 (31%), Positives = 30/57 (52%)
Frame = -1
Query: 488 VEGELIIRQGDTADGMYFVEDGSVSIRITRDDGNEHEIKRLGKGDYFGELALVTHKP 318
++G+ ++ GD +YF+ GS+ I N+ + LGK D FGE+ + KP
Sbjct: 767 LQGDTLVHCGDVLTALYFLSRGSIEI-----SKNDMVVAILGKNDIFGEMVHLYAKP 818
>S76067-1|AAD14207.1| 261|Homo sapiens CNG2 protein.
Length = 261
Score = 35.9 bits (79), Expect = 0.16
Identities = 19/62 (30%), Positives = 33/62 (53%)
Frame = -1
Query: 506 LLPRTLVEGELIIRQGDTADGMYFVEDGSVSIRITRDDGNEHEIKRLGKGDYFGELALVT 327
L P+ G+ I R+GD MY +++G ++ + DDG + L G FGE++++
Sbjct: 179 LRPQVFSPGDYICRKGDIGKEMYIIKEGKLA--VVADDG-VTQYALLSAGSCFGEISILN 235
Query: 326 HK 321
K
Sbjct: 236 IK 237
>BC126304-1|AAI26305.1| 664|Homo sapiens cyclic nucleotide gated
channel alpha 2 protein.
Length = 664
Score = 35.9 bits (79), Expect = 0.16
Identities = 19/62 (30%), Positives = 33/62 (53%)
Frame = -1
Query: 506 LLPRTLVEGELIIRQGDTADGMYFVEDGSVSIRITRDDGNEHEIKRLGKGDYFGELALVT 327
L P+ G+ I R+GD MY +++G ++ + DDG + L G FGE++++
Sbjct: 470 LRPQVFSPGDYICRKGDIGKEMYIIKEGKLA--VVADDG-VTQYALLSAGSCFGEISILN 526
Query: 326 HK 321
K
Sbjct: 527 IK 528
>BC126302-1|AAI26303.1| 664|Homo sapiens cyclic nucleotide gated
channel alpha 2 protein.
Length = 664
Score = 35.9 bits (79), Expect = 0.16
Identities = 19/62 (30%), Positives = 33/62 (53%)
Frame = -1
Query: 506 LLPRTLVEGELIIRQGDTADGMYFVEDGSVSIRITRDDGNEHEIKRLGKGDYFGELALVT 327
L P+ G+ I R+GD MY +++G ++ + DDG + L G FGE++++
Sbjct: 470 LRPQVFSPGDYICRKGDIGKEMYIIKEGKLA--VVADDG-VTQYALLSAGSCFGEISILN 526
Query: 326 HK 321
K
Sbjct: 527 IK 528
>BC073979-1|AAH73979.1| 988|Homo sapiens potassium voltage-gated
channel, subfamily H (eag-related), member 5 protein.
Length = 988
Score = 34.3 bits (75), Expect = 0.50
Identities = 18/48 (37%), Positives = 28/48 (58%)
Frame = -1
Query: 482 GELIIRQGDTADGMYFVEDGSVSIRITRDDGNEHEIKRLGKGDYFGEL 339
G+LI G++ D + FV GS + + +DD + LGKGD FG++
Sbjct: 574 GDLIYHAGESVDALCFVVSGS--LEVIQDD---EVVAILGKGDVFGDI 616
>AF472412-1|AAM49565.1| 988|Homo sapiens potassium channel HEAG2
protein.
Length = 988
Score = 34.3 bits (75), Expect = 0.50
Identities = 18/48 (37%), Positives = 28/48 (58%)
Frame = -1
Query: 482 GELIIRQGDTADGMYFVEDGSVSIRITRDDGNEHEIKRLGKGDYFGEL 339
G+LI G++ D + FV GS + + +DD + LGKGD FG++
Sbjct: 574 GDLIYHAGESVDALCFVVSGS--LEVIQDD---EVVAILGKGDVFGDI 616
>AF418206-1|AAM28435.1| 988|Homo sapiens voltage-gated potassium
channel EAG2 protein.
Length = 988
Score = 34.3 bits (75), Expect = 0.50
Identities = 18/48 (37%), Positives = 28/48 (58%)
Frame = -1
Query: 482 GELIIRQGDTADGMYFVEDGSVSIRITRDDGNEHEIKRLGKGDYFGEL 339
G+LI G++ D + FV GS + + +DD + LGKGD FG++
Sbjct: 574 GDLIYHAGESVDALCFVVSGS--LEVIQDD---EVVAILGKGDVFGDI 616
>AC007740-1|AAX93153.1| 940|Homo sapiens unknown protein.
Length = 940
Score = 34.3 bits (75), Expect = 0.50
Identities = 20/55 (36%), Positives = 29/55 (52%)
Frame = -1
Query: 482 GELIIRQGDTADGMYFVEDGSVSIRITRDDGNEHEIKRLGKGDYFGELALVTHKP 318
G+ ++ GD +YF+ G SI I +DD + LGK D FGE+ + KP
Sbjct: 666 GDTLVHCGDVLTALYFLSRG--SIEILKDD---IVVAILGKNDIFGEMVHLYAKP 715
>M84741-1|AAA52010.1| 690|Homo sapiens cGMP-gated cation channel
protein protein.
Length = 690
Score = 33.9 bits (74), Expect = 0.66
Identities = 18/62 (29%), Positives = 33/62 (53%)
Frame = -1
Query: 506 LLPRTLVEGELIIRQGDTADGMYFVEDGSVSIRITRDDGNEHEIKRLGKGDYFGELALVT 327
L P+ G+ I ++GD MY +++G ++ + DDG + L G FGE++++
Sbjct: 495 LQPQVYSPGDYICKKGDIGREMYIIKEGKLA--VVADDGVTQFVV-LSDGSTFGEISILN 551
Query: 326 HK 321
K
Sbjct: 552 IK 553
>BC113709-1|AAI13710.1| 962|Homo sapiens potassium voltage-gated
channel, subfamily H (eag-related), member 1 protein.
Length = 962
Score = 33.9 bits (74), Expect = 0.66
Identities = 18/48 (37%), Positives = 28/48 (58%)
Frame = -1
Query: 482 GELIIRQGDTADGMYFVEDGSVSIRITRDDGNEHEIKRLGKGDYFGEL 339
G+LI G++ D + FV GS + + +DD + LGKGD FG++
Sbjct: 578 GDLIYHAGESVDSLCFVVSGS--LEVIQDD---EVVAILGKGDVFGDV 620
>AL590132-2|CAH71752.1| 962|Homo sapiens potassium voltage-gated
channel, subfamily H (eag-related), member 1 protein.
Length = 962
Score = 33.9 bits (74), Expect = 0.66
Identities = 18/48 (37%), Positives = 28/48 (58%)
Frame = -1
Query: 482 GELIIRQGDTADGMYFVEDGSVSIRITRDDGNEHEIKRLGKGDYFGEL 339
G+LI G++ D + FV GS + + +DD + LGKGD FG++
Sbjct: 578 GDLIYHAGESVDSLCFVVSGS--LEVIQDD---EVVAILGKGDVFGDV 620
>AL590132-1|CAH71753.1| 989|Homo sapiens potassium voltage-gated
channel, subfamily H (eag-related), member 1 protein.
Length = 989
Score = 33.9 bits (74), Expect = 0.66
Identities = 18/48 (37%), Positives = 28/48 (58%)
Frame = -1
Query: 482 GELIIRQGDTADGMYFVEDGSVSIRITRDDGNEHEIKRLGKGDYFGEL 339
G+LI G++ D + FV GS + + +DD + LGKGD FG++
Sbjct: 605 GDLIYHAGESVDSLCFVVSGS--LEVIQDD---EVVAILGKGDVFGDV 647
>AK091877-1|BAC03764.1| 905|Homo sapiens protein ( Homo sapiens
cDNA FLJ34558 fis, clone KIDNE2001636, highly similar to
Rattus norvegicus potassium channel (erg2) mRNA. ).
Length = 905
Score = 33.9 bits (74), Expect = 0.66
Identities = 21/59 (35%), Positives = 30/59 (50%)
Frame = -1
Query: 482 GELIIRQGDTADGMYFVEDGSVSIRITRDDGNEHEIKRLGKGDYFGELALVTHKPRAAS 306
G+ ++ GD +YF+ G SI I RDD + LGK D FGE + +P +S
Sbjct: 565 GDTLVHLGDVLSTLYFISRG--SIEILRDD---VVVAILGKNDIFGEPVSLHAQPGKSS 618
>AK090969-1|BAC03559.1| 430|Homo sapiens protein ( Homo sapiens
cDNA FLJ33650 fis, clone BRAMY2024514, highly similar to
Rattus norvegicus potassium channel (erg2) mRNA. ).
Length = 430
Score = 33.9 bits (74), Expect = 0.66
Identities = 21/59 (35%), Positives = 30/59 (50%)
Frame = -1
Query: 482 GELIIRQGDTADGMYFVEDGSVSIRITRDDGNEHEIKRLGKGDYFGELALVTHKPRAAS 306
G+ ++ GD +YF+ G SI I RDD + LGK D FGE + +P +S
Sbjct: 90 GDTLVHLGDVLSTLYFISRG--SIEILRDD---VVVAILGKNDIFGEPVSLHAQPGKSS 143
>AJ001366-1|CAA04700.1| 962|Homo sapiens protein ( Homo sapiens
potassium channel h-eag. ).
Length = 962
Score = 33.9 bits (74), Expect = 0.66
Identities = 18/48 (37%), Positives = 28/48 (58%)
Frame = -1
Query: 482 GELIIRQGDTADGMYFVEDGSVSIRITRDDGNEHEIKRLGKGDYFGEL 339
G+LI G++ D + FV GS + + +DD + LGKGD FG++
Sbjct: 578 GDLIYHAGESVDSLCFVVSGS--LEVIQDD---EVVAILGKGDVFGDV 620
>AF311913-1|AAG40871.1| 994|Homo sapiens Eag-related gene member 2
protein.
Length = 994
Score = 33.9 bits (74), Expect = 0.66
Identities = 21/59 (35%), Positives = 30/59 (50%)
Frame = -1
Query: 482 GELIIRQGDTADGMYFVEDGSVSIRITRDDGNEHEIKRLGKGDYFGELALVTHKPRAAS 306
G+ ++ GD +YF+ G SI I RDD + LGK D FGE + +P +S
Sbjct: 618 GDTLVHLGDVLSTLYFISRG--SIEILRDD---VVVAILGKNDIFGEPVSLHAQPGKSS 671
>AF078742-1|AAC68669.1| 989|Homo sapiens voltage-gated potassium
channel eagB protein.
Length = 989
Score = 33.9 bits (74), Expect = 0.66
Identities = 18/48 (37%), Positives = 28/48 (58%)
Frame = -1
Query: 482 GELIIRQGDTADGMYFVEDGSVSIRITRDDGNEHEIKRLGKGDYFGEL 339
G+LI G++ D + FV GS + + +DD + LGKGD FG++
Sbjct: 605 GDLIYHAGESVDSLCFVVSGS--LEVIQDD---EVVAILGKGDVFGDV 647
>AF078741-1|AAC68668.1| 962|Homo sapiens voltage-gated potassium
channel eag protein.
Length = 962
Score = 33.9 bits (74), Expect = 0.66
Identities = 18/48 (37%), Positives = 28/48 (58%)
Frame = -1
Query: 482 GELIIRQGDTADGMYFVEDGSVSIRITRDDGNEHEIKRLGKGDYFGEL 339
G+LI G++ D + FV GS + + +DD + LGKGD FG++
Sbjct: 578 GDLIYHAGESVDSLCFVVSGS--LEVIQDD---EVVAILGKGDVFGDV 620
>AY053503-1|AAL15429.1| 1107|Homo sapiens ether-a-go-go-like
potassium channel 1 protein.
Length = 1107
Score = 31.5 bits (68), Expect = 3.5
Identities = 18/46 (39%), Positives = 25/46 (54%)
Frame = -1
Query: 482 GELIIRQGDTADGMYFVEDGSVSIRITRDDGNEHEIKRLGKGDYFG 345
GE ++RQGD +YFV G S+ + +D + LGKGD G
Sbjct: 575 GEYLLRQGDALQAIYFVCSG--SMEVLKD---SMVLAILGKGDLIG 615
>AB209053-1|BAD92290.1| 583|Homo sapiens potassium voltage-gated
channel, subfamily H, member 8 variant protein.
Length = 583
Score = 31.5 bits (68), Expect = 3.5
Identities = 18/46 (39%), Positives = 25/46 (54%)
Frame = -1
Query: 482 GELIIRQGDTADGMYFVEDGSVSIRITRDDGNEHEIKRLGKGDYFG 345
GE ++RQGD +YFV G S+ + +D + LGKGD G
Sbjct: 51 GEYLLRQGDALQAIYFVCSG--SMEVLKD---SMVLAILGKGDLIG 91
>U04270-1|AAA62473.1| 1159|Homo sapiens putative potassium channel
subunit protein.
Length = 1159
Score = 30.7 bits (66), Expect = 6.1
Identities = 18/47 (38%), Positives = 24/47 (51%)
Frame = -1
Query: 482 GELIIRQGDTADGMYFVEDGSVSIRITRDDGNEHEIKRLGKGDYFGE 342
G+ ++ GD +YF+ G SI I R D + LGK D FGE
Sbjct: 766 GDTLVHAGDLLTALYFISRG--SIEILRGD---VVVAILGKNDIFGE 807
>DQ784808-1|ABQ01243.1| 1159|Homo sapiens potassium voltage-gated
channel subfamily H member 2 protein.
Length = 1159
Score = 30.7 bits (66), Expect = 6.1
Identities = 18/47 (38%), Positives = 24/47 (51%)
Frame = -1
Query: 482 GELIIRQGDTADGMYFVEDGSVSIRITRDDGNEHEIKRLGKGDYFGE 342
G+ ++ GD +YF+ G SI I R D + LGK D FGE
Sbjct: 766 GDTLVHAGDLLTALYFISRG--SIEILRGD---VVVAILGKNDIFGE 807
>DQ525913-1|ABF71886.1| 1159|Homo sapiens voltage-gated potassium
channel KV11.1 transcript variant 1 protein.
Length = 1159
Score = 30.7 bits (66), Expect = 6.1
Identities = 18/47 (38%), Positives = 24/47 (51%)
Frame = -1
Query: 482 GELIIRQGDTADGMYFVEDGSVSIRITRDDGNEHEIKRLGKGDYFGE 342
G+ ++ GD +YF+ G SI I R D + LGK D FGE
Sbjct: 766 GDTLVHAGDLLTALYFISRG--SIEILRGD---VVVAILGKNDIFGE 807
>BC004311-1|AAH04311.2| 444|Homo sapiens KCNH2 protein protein.
Length = 444
Score = 30.7 bits (66), Expect = 6.1
Identities = 18/47 (38%), Positives = 24/47 (51%)
Frame = -1
Query: 482 GELIIRQGDTADGMYFVEDGSVSIRITRDDGNEHEIKRLGKGDYFGE 342
G+ ++ GD +YF+ G SI I R D + LGK D FGE
Sbjct: 51 GDTLVHAGDLLTALYFISRG--SIEILRGD---VVVAILGKNDIFGE 92
>AJ512214-1|CAD54447.1| 819|Homo sapiens potassium channel 1b
protein protein.
Length = 819
Score = 30.7 bits (66), Expect = 6.1
Identities = 18/47 (38%), Positives = 24/47 (51%)
Frame = -1
Query: 482 GELIIRQGDTADGMYFVEDGSVSIRITRDDGNEHEIKRLGKGDYFGE 342
G+ ++ GD +YF+ G SI I R D + LGK D FGE
Sbjct: 426 GDTLVHAGDLLTALYFISRG--SIEILRGD---VVVAILGKNDIFGE 467
>AJ010538-1|CAA09232.1| 1133|Homo sapiens ether-a-go-go-related
protein protein.
Length = 1133
Score = 30.7 bits (66), Expect = 6.1
Identities = 18/47 (38%), Positives = 24/47 (51%)
Frame = -1
Query: 482 GELIIRQGDTADGMYFVEDGSVSIRITRDDGNEHEIKRLGKGDYFGE 342
G+ ++ GD +YF+ G SI I R D + LGK D FGE
Sbjct: 740 GDTLVHAGDLLTALYFISRG--SIEILRGD---VVVAILGKNDIFGE 781
>AF363636-1|AAL37559.1| 1159|Homo sapiens ether-a-go-go-related K+
channel protein protein.
Length = 1159
Score = 30.7 bits (66), Expect = 6.1
Identities = 18/47 (38%), Positives = 24/47 (51%)
Frame = -1
Query: 482 GELIIRQGDTADGMYFVEDGSVSIRITRDDGNEHEIKRLGKGDYFGE 342
G+ ++ GD +YF+ G SI I R D + LGK D FGE
Sbjct: 766 GDTLVHAGDLLTALYFISRG--SIEILRGD---VVVAILGKNDIFGE 807
>AB009071-1|BAA37096.1| 1159|Homo sapiens HERG protein.
Length = 1159
Score = 30.7 bits (66), Expect = 6.1
Identities = 18/47 (38%), Positives = 24/47 (51%)
Frame = -1
Query: 482 GELIIRQGDTADGMYFVEDGSVSIRITRDDGNEHEIKRLGKGDYFGE 342
G+ ++ GD +YF+ G SI I R D + LGK D FGE
Sbjct: 766 GDTLVHAGDLLTALYFISRG--SIEILRGD---VVVAILGKNDIFGE 807
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 108,987,091
Number of Sequences: 237096
Number of extensions: 2151327
Number of successful extensions: 5443
Number of sequences better than 10.0: 111
Number of HSP's better than 10.0 without gapping: 4946
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5320
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 9478778060
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
- SilkBase 1999-2023 -