Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P14_F_O10
(805 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC067430-1|AAH67430.1| 491|Homo sapiens cytochrome P450, family... 83 1e-15
BC067431-1|AAH67431.1| 491|Homo sapiens cytochrome P450, family... 81 3e-15
M29874-1|AAA52144.1| 491|Homo sapiens CYP2B protein. 81 5e-15
DQ298753-1|ABB84469.1| 491|Homo sapiens cytochrome P450, family... 81 5e-15
AC023172-1|AAF32444.1| 491|Homo sapiens CYP2B6 protein. 81 5e-15
AF182277-1|AAF13602.1| 491|Homo sapiens cytochrome P450-2B6 pro... 80 8e-15
AY220845-1|AAO49806.1| 516|Homo sapiens cytochrome P450 protein. 50 1e-13
BC104909-1|AAI04910.1| 501|Homo sapiens cytochrome P450, family... 57 3e-13
BC104907-1|AAI04908.1| 501|Homo sapiens cytochrome P450, family... 57 3e-13
AY323817-1|AAQ23114.1| 501|Homo sapiens cytochrome P450 2R1 pro... 57 3e-13
BC132767-1|AAI32768.1| 544|Homo sapiens cytochrome P450, family... 57 4e-13
AY343323-1|AAQ21380.1| 544|Homo sapiens cytochrome P450 protein. 57 4e-13
DQ282158-1|ABB77906.1| 497|Homo sapiens cytochrome P450 2D6 pro... 48 7e-13
DQ282157-1|ABB77905.1| 497|Homo sapiens cytochrome P450 2D6 pro... 48 7e-13
X08006-1|CAA30807.1| 497|Homo sapiens cytochrome P450 db1 protein. 48 9e-13
M33388-1|AAA53500.1| 497|Homo sapiens cytochrome P450 IID6 prot... 48 9e-13
M20403-1|AAA52153.1| 497|Homo sapiens CYP2D protein. 48 9e-13
DQ282160-1|ABB77908.1| 497|Homo sapiens cytochrome P450 2D6 pro... 48 9e-13
DQ282159-1|ABB77907.1| 497|Homo sapiens cytochrome P450 2D6 pro... 48 9e-13
DQ282156-1|ABB77904.1| 497|Homo sapiens cytochrome P450 2D6 pro... 48 9e-13
DQ282153-1|ABB77901.1| 497|Homo sapiens cytochrome P450 2D6 pro... 48 9e-13
DQ282147-1|ABB77898.1| 497|Homo sapiens cytochrome P450 2D6 pro... 48 9e-13
DQ282146-1|ABB77897.1| 497|Homo sapiens cytochrome P450 2D6 pro... 48 9e-13
DQ282145-1|ABB77896.1| 497|Homo sapiens cytochrome P450 2D6 pro... 48 9e-13
DQ282144-1|ABB77895.1| 497|Homo sapiens cytochrome P450 2D6 pro... 48 9e-13
BC126858-1|AAI26859.1| 497|Homo sapiens cytochrome P450, family... 48 9e-13
BC106758-1|AAI06759.1| 497|Homo sapiens cytochrome P450, family... 48 9e-13
BC075024-1|AAH75024.1| 497|Homo sapiens cytochrome P450, family... 48 9e-13
BC075023-1|AAH75023.1| 497|Homo sapiens cytochrome P450, family... 48 9e-13
BC067432-1|AAH67432.1| 497|Homo sapiens cytochrome P450, family... 48 9e-13
AY545216-1|AAS55001.1| 497|Homo sapiens cytochrome P4502D6 prot... 48 9e-13
DQ282151-1|ABB77899.1| 496|Homo sapiens cytochrome P450 2D6 pro... 48 9e-13
DQ282154-1|ABB77902.1| 497|Homo sapiens cytochrome P450 2D6 pro... 48 1e-12
EF122242-1|ABO41977.1| 321|Homo sapiens cytochrome P450 2F1 var... 73 1e-12
CR456430-1|CAG30316.1| 446|Homo sapiens CYP2D6 protein. 72 2e-12
BC106757-1|AAI06758.1| 446|Homo sapiens cytochrome P450, family... 72 2e-12
BC066877-1|AAH66877.1| 446|Homo sapiens CYP2D6 protein protein. 72 2e-12
J02906-1|AAA52156.1| 491|Homo sapiens CYP2F1 protein. 46 6e-12
DQ282152-1|ABB77900.1| 497|Homo sapiens cytochrome P450 2D6 pro... 48 8e-12
DQ211354-2|ABB01372.1| 497|Homo sapiens cytochrome P450 2D6 pro... 48 8e-12
DQ211353-2|ABB01371.1| 497|Homo sapiens cytochrome P450 2D6 pro... 48 8e-12
DQ211353-1|ABB01370.1| 497|Homo sapiens cytochrome P450 2D6 pro... 48 8e-12
M61856-1|AAB59356.1| 490|Homo sapiens cytochrome protein. 48 8e-12
L16876-1|AAA02630.1| 490|Homo sapiens cytochrome P-4502C18 prot... 48 8e-12
BC096258-1|AAH96258.1| 490|Homo sapiens cytochrome P450, family... 48 8e-12
BC096257-1|AAH96257.1| 490|Homo sapiens cytochrome P450, family... 48 8e-12
BC069666-1|AAH69666.1| 490|Homo sapiens cytochrome P450, family... 48 8e-12
AL583836-1|CAH74067.1| 490|Homo sapiens cytochrome P450, family... 48 8e-12
BC096259-1|AAH96259.1| 443|Homo sapiens CYP2C18 protein protein. 48 8e-12
M33317-1|AAA52138.1| 494|Homo sapiens CYP2A protein. 70 9e-12
EF122241-1|ABO41976.1| 491|Homo sapiens cytochrome P450 2F1 var... 69 2e-11
AK223510-1|BAD97230.1| 490|Homo sapiens cytochrome P450, family... 48 2e-11
BC117165-1|AAI17166.1| 494|Homo sapiens cytochrome P450, family... 68 5e-11
BC109056-1|AAI09057.1| 320|Homo sapiens CYP2F1 protein protein. 68 5e-11
U22029-1|AAB40520.1| 494|Homo sapiens cytochrome P450 protein. 67 6e-11
AK223113-1|BAD96833.1| 512|Homo sapiens cytochrome P450, family... 64 7e-10
AK223108-1|BAD96828.1| 512|Homo sapiens cytochrome P450, family... 64 7e-10
X04300-1|CAA27843.1| 512|Homo sapiens P-450 c protein. 63 1e-09
X02612-1|CAA26458.1| 512|Homo sapiens cytochrome P(1)-450 protein. 63 1e-09
K03191-1|AAA52139.1| 512|Homo sapiens CYP1A1 protein. 63 1e-09
EF094025-1|ABK41999.1| 512|Homo sapiens cytochrome P450, family... 63 1e-09
BC023019-1|AAH23019.1| 512|Homo sapiens cytochrome P450, family... 63 1e-09
AY310359-1|AAQ76692.1| 484|Homo sapiens cytochrome P450 1A1 var... 63 1e-09
AM236046-1|CAJ84703.1| 229|Homo sapiens cytochrome P450 1A1 pro... 63 1e-09
AM233520-1|CAJ80723.1| 189|Homo sapiens cytochrome P450 1A1 pro... 63 1e-09
AM233519-1|CAJ80722.1| 189|Homo sapiens cytochrome P450 1A1 pro... 63 1e-09
AF253322-1|AAK25727.1| 512|Homo sapiens cytochrome P450 protein. 63 1e-09
AY871801-1|AAX62803.1| 483|Homo sapiens cytochrome P450 family ... 63 1e-09
X13930-1|CAA32118.1| 494|Homo sapiens protein ( Human CYP2A4 mR... 62 2e-09
BC096255-1|AAH96255.1| 494|Homo sapiens cytochrome P450, family... 62 2e-09
AF372573-1|AAL69652.1| 495|Homo sapiens cytochrome P450 2F1 pro... 62 2e-09
X13897-1|CAA32097.1| 489|Homo sapiens protein ( Human mRNA for ... 62 3e-09
M33318-1|AAA52067.1| 494|Homo sapiens CYP2A protein. 62 3e-09
BC096256-1|AAH96256.1| 494|Homo sapiens cytochrome P450, family... 62 3e-09
BC096254-1|AAH96254.1| 494|Homo sapiens cytochrome P450, family... 62 3e-09
BC096253-1|AAH96253.3| 494|Homo sapiens cytochrome P450, family... 62 3e-09
AF182275-1|AAF13600.1| 494|Homo sapiens cytochrome P450-2A6 pro... 62 3e-09
U22027-1|AAB40518.1| 494|Homo sapiens cytochrome P450 protein. 61 4e-09
U37143-1|AAC50370.2| 502|Homo sapiens cytochrome P450 monooxyge... 58 3e-08
BC032594-1|AAH32594.1| 502|Homo sapiens cytochrome P450, family... 58 3e-08
AY426985-1|AAQ93356.1| 502|Homo sapiens cytochrome P450, family... 58 3e-08
AF272142-1|AAM44456.1| 502|Homo sapiens cytochrome P450 protein. 58 3e-08
AF144566-1|AAD30164.1| 339|Homo sapiens cytochrome P450 epoxyge... 58 3e-08
AB080265-1|BAB85489.1| 502|Homo sapiens cytochrome P450 2J2 pro... 58 3e-08
S46963-1|AAB23864.2| 477|Homo sapiens cytochrome P-450 protein. 58 5e-08
M29873-1|AAA52143.1| 377|Homo sapiens CYP2B protein. 58 5e-08
M21939-1|AAA52158.1| 485|Homo sapiens CYP2C protein. 58 5e-08
M15331-1|AAA52157.1| 485|Homo sapiens CYP2C protein. 58 5e-08
D00173-1|BAA00123.1| 487|Homo sapiens cytochrome P-450 protein. 58 5e-08
BC125054-1|AAI25055.1| 490|Homo sapiens cytochrome P450, family... 58 5e-08
BC041174-1|AAH41174.1| 377|Homo sapiens CYP2B7P1 protein protein. 58 5e-08
AY702706-1|AAT94065.1| 490|Homo sapiens cytochrome P450, family... 58 5e-08
AY341248-1|AAP88931.1| 490|Homo sapiens cytochrome P450, family... 58 5e-08
AL359672-1|CAH71303.1| 490|Homo sapiens cytochrome P450, family... 58 5e-08
AF182276-1|AAF13601.1| 493|Homo sapiens cytochrome P450-2E1 pro... 57 9e-08
L16880-1|AAD13466.1| 273|Homo sapiens cytochrome P-450 2C protein. 56 1e-07
J02843-1|AAA52155.1| 493|Homo sapiens protein ( Human cytochrom... 56 1e-07
J02625-1|AAA35743.1| 493|Homo sapiens protein ( Human cytochrom... 56 1e-07
DQ515958-1|ABF47105.1| 493|Homo sapiens cytochrome P450, family... 56 1e-07
DQ149222-1|AAZ77710.1| 493|Homo sapiens cytochrome P450 2E1 pro... 56 1e-07
BC067435-1|AAH67435.1| 493|Homo sapiens cytochrome P450, family... 56 1e-07
AL161645-2|CAH70047.1| 493|Homo sapiens cytochrome P450, family... 56 1e-07
BC067433-1|AAH67433.1| 493|Homo sapiens cytochrome P450, family... 56 1e-07
AY513608-1|AAR90939.1| 494|Homo sapiens cytochrome P450 2A13 va... 56 1e-07
AF084225-1|AAD13753.1| 462|Homo sapiens cytochrome P450 2E1 pro... 56 1e-07
U22028-1|AAB40519.1| 494|Homo sapiens cytochrome P450 protein. 56 2e-07
AY513609-1|AAR90940.1| 494|Homo sapiens cytochrome P450 2A13 va... 55 3e-07
AY513606-1|AAR90937.1| 494|Homo sapiens cytochrome P450 2A13 va... 55 3e-07
AY513605-1|AAR90936.1| 494|Homo sapiens cytochrome P450 2A13 va... 55 3e-07
AY513604-1|AAR90935.1| 494|Homo sapiens cytochrome P450 2A13 va... 55 3e-07
AF209774-1|AAG35775.1| 494|Homo sapiens cytochrome P450 2A13 pr... 55 3e-07
M61854-1|AAB59426.1| 490|Homo sapiens cytochrome protein. 54 8e-07
AY796203-1|AAV41877.1| 490|Homo sapiens cytochrome P450, family... 54 8e-07
AL583836-2|CAH74068.1| 490|Homo sapiens cytochrome P450, family... 54 8e-07
AL133513-2|CAH73444.1| 490|Homo sapiens cytochrome P450, family... 54 8e-07
Z00036-1|CAA77335.1| 515|Homo sapiens protein ( Human mRNA for ... 52 2e-06
M55053-1|AAA52146.1| 515|Homo sapiens cytochrome P3-450 protein. 52 2e-06
M31667-1|AAA52163.1| 515|Homo sapiens CYP1A2 protein. 52 2e-06
DQ022432-1|AAY26399.1| 516|Homo sapiens cytochrome P450, family... 52 2e-06
BC067429-1|AAH67429.1| 516|Homo sapiens cytochrome P450, family... 52 2e-06
BC067428-1|AAH67428.1| 516|Homo sapiens cytochrome P450, family... 52 2e-06
BC067426-1|AAH67426.1| 516|Homo sapiens cytochrome P450, family... 52 2e-06
BC067425-1|AAH67425.1| 516|Homo sapiens cytochrome P450, family... 52 2e-06
BC067424-1|AAH67424.1| 516|Homo sapiens cytochrome P450, family... 52 2e-06
AF253322-2|AAK25728.1| 516|Homo sapiens cytochrome P450 protein. 52 2e-06
AF182274-1|AAF13599.1| 516|Homo sapiens cytochrome P450-1A2 pro... 52 2e-06
X65962-1|CAA46778.1| 356|Homo sapiens cytochrome P-450 II C pro... 52 3e-06
X13929-1|CAA32117.1| 448|Homo sapiens P-450 IIA3 protein (1 is ... 52 3e-06
BC033691-1|AAH33691.1| 504|Homo sapiens cytochrome P450, family... 52 3e-06
AY358603-1|AAQ88966.1| 504|Homo sapiens Cytochrome p450 protein. 52 3e-06
AK027605-1|BAB55227.1| 564|Homo sapiens protein ( Homo sapiens ... 52 3e-06
AF335278-1|AAK13498.1| 504|Homo sapiens cytochrome P450 2S1 pro... 52 3e-06
M21941-1|AAA52160.1| 480|Homo sapiens CYP2C protein. 51 6e-06
Y00498-1|CAA68550.1| 490|Homo sapiens IIC2 protein. 50 1e-05
L00389-1|AAA35738.1| 516|Homo sapiens protein ( Human cytochrom... 50 1e-05
BC020596-1|AAH20596.1| 490|Homo sapiens cytochrome P450, family... 50 1e-05
AY514490-1|AAR89907.1| 490|Homo sapiens cytochrome P450, family... 50 1e-05
AL359672-5|CAH71307.1| 490|Homo sapiens cytochrome P450, family... 50 1e-05
BC067427-1|AAH67427.1| 516|Homo sapiens cytochrome P450, family... 50 1e-05
M17398-1|AAA35740.1| 393|Homo sapiens protein ( Human cytochrom... 49 2e-05
M17397-1|AAA35739.1| 490|Homo sapiens protein ( Human cytochrom... 49 2e-05
M61858-1|AAA52145.1| 370|Homo sapiens CYP2C17 protein. 48 4e-05
M24499-1|AAA36403.1| 373|Homo sapiens cytochrome P450db1 protein. 48 4e-05
M21942-1|AAA52161.1| 462|Homo sapiens CYP2C protein. 48 4e-05
M21940-1|AAA52159.1| 383|Homo sapiens CYP2C protein. 47 9e-05
L07093-1|AAA36660.1| 468|Homo sapiens cytochrome P450 protein. 46 1e-04
DQ282155-1|ABB77903.1| 497|Homo sapiens cytochrome P450 2D6 pro... 46 1e-04
DQ282162-1|ABB77909.1| 500|Homo sapiens cytochrome P450 2D6 pro... 46 2e-04
AY513607-1|AAR90938.1| 100|Homo sapiens truncated cytochrome P4... 45 3e-04
BC025761-1|AAH25761.2| 490|Homo sapiens cytochrome P450, family... 44 9e-04
U56438-1|AAC50809.1| 543|Homo sapiens dioxin-inducible cytochro... 43 0.001
U03688-1|AAA19567.1| 543|Homo sapiens cytochrome P450 protein. 43 0.001
L39098-1|AAL31347.1| 160|Homo sapiens S-mephenytoin 4-hydroxyla... 43 0.001
BT019979-1|AAV38782.1| 543|Homo sapiens cytochrome P450, family... 43 0.001
BC109084-1|AAI09085.1| 448|Homo sapiens CYP24A1 protein protein. 43 0.001
BC109083-1|AAI09084.1| 448|Homo sapiens CYP24A1 protein protein. 43 0.001
BC012049-1|AAH12049.1| 543|Homo sapiens cytochrome P450, family... 43 0.001
AY393998-1|AAQ87875.1| 543|Homo sapiens cytochrome P450, family... 43 0.001
AL138805-3|CAM27343.1| 448|Homo sapiens cytochrome P450, family... 43 0.001
AL138805-2|CAB91829.1| 514|Homo sapiens cytochrome P450, family... 43 0.001
AF450132-1|AAM50512.1| 543|Homo sapiens cytochrome P450 CYP1B1 ... 43 0.001
AC009229-2|AAY15039.1| 543|Homo sapiens unknown protein. 43 0.001
BC070317-1|AAH70317.1| 162|Homo sapiens CYP2C9 protein protein. 43 0.001
BC020754-1|AAH20754.1| 162|Homo sapiens CYP2C9 protein protein. 43 0.001
AB209700-1|BAD92937.1| 336|Homo sapiens cytochrome P450, family... 43 0.001
S63426-1|ABB76283.1| 214|Homo sapiens (S)-mephenytoin hydroxyla... 42 0.002
DQ359216-1|ABC95161.1| 347|Homo sapiens dioxin-inducible cytoch... 42 0.002
DQ211355-2|ABB01373.1| 117|Homo sapiens cytochrome P450 2D6 pro... 42 0.002
BT020001-1|AAV38804.1| 543|Homo sapiens cytochrome P450, family... 42 0.002
BC096260-1|AAH96260.1| 431|Homo sapiens CYP2C18 protein protein. 42 0.002
M33189-1|AAA35737.1| 500|Homo sapiens protein ( Human debrisoqu... 42 0.003
J04813-1|AAA02993.1| 502|Homo sapiens cytochrome P450 PCN3 prot... 42 0.003
DQ680079-1|ABG25922.1| 347|Homo sapiens truncated cytochrome P4... 42 0.003
DQ372705-1|ABD16216.1| 150|Homo sapiens mutant cytochrome p450 ... 42 0.003
BC033862-1|AAH33862.1| 502|Homo sapiens cytochrome P450, family... 42 0.003
AK223008-1|BAD96728.1| 502|Homo sapiens cytochrome P450, family... 42 0.003
AF280107-4|AAG32288.1| 106|Homo sapiens cytochrome P450 polypep... 42 0.003
AC005020-1|AAS02016.1| 502|Homo sapiens unknown protein. 42 0.003
L13286-1|AAA62379.1| 513|Homo sapiens 1,25-dihydroxyvitamin D3 ... 41 0.006
AF171066-1|AAG43404.1| 112|Homo sapiens CYP1B1 variant protein. 39 0.018
J04449-1|AAA35747.1| 502|Homo sapiens cytochrome P450 nifedipin... 38 0.042
BC012027-1|AAH12027.1| 168|Homo sapiens CYP2U1 protein protein. 38 0.042
X12387-1|CAA30944.1| 503|Homo sapiens protein ( Human mRNA for ... 38 0.056
M18907-1|AAA35745.1| 503|Homo sapiens protein ( Human P450 mRNA... 38 0.056
M14096-1|AAA35744.1| 503|Homo sapiens protein ( Human cytochrom... 38 0.056
K03192-1|AAA52147.1| 331|Homo sapiens CYP1A1 protein. 38 0.056
DQ924960-1|ABI96208.1| 503|Homo sapiens cytochrome P450 family ... 38 0.056
DQ005611-1|AAY16980.1| 503|Homo sapiens cytochrome P450, family... 38 0.056
BC101631-1|AAI01632.1| 503|Homo sapiens cytochrome P450, subfam... 38 0.056
BC069418-1|AAH69418.1| 503|Homo sapiens cytochrome P450, family... 38 0.056
AJ563375-1|CAD91343.1| 503|Homo sapiens cytochrome P450 protein. 38 0.056
AF280107-2|AAG32290.1| 503|Homo sapiens cytochrome P450 polypep... 38 0.056
AF209389-1|AAF21034.1| 503|Homo sapiens cytochrome P450 IIIA4 p... 38 0.056
AF182273-1|AAF13598.1| 503|Homo sapiens cytochrome P450-3A4 pro... 38 0.056
M13785-1|AAA35742.1| 504|Homo sapiens protein ( Human liver glu... 37 0.098
D00003-1|BAA00001.1| 504|Homo sapiens cytochrome P-450 protein. 37 0.098
AB209492-1|BAD92729.1| 566|Homo sapiens Debrisoquine 4-hydroxyl... 30 0.21
X54807-1|CAA38578.1| 56|Homo sapiens unspecific monooxygenase ... 36 0.23
AY390425-1|AAQ92353.1| 503|Homo sapiens cytochrome P450 CYP3A43... 36 0.23
AY390424-1|AAQ92352.1| 503|Homo sapiens cytochrome P450 CYP3A43... 36 0.23
AF337813-1|AAK38841.1| 503|Homo sapiens cytochrome P450 subfami... 36 0.23
AF319634-1|AAK00325.1| 503|Homo sapiens cytochrome P450 CYP3A43... 36 0.23
AF280111-1|AAG33012.1| 250|Homo sapiens cytochrome P450 subfami... 36 0.23
AF280110-1|AAG33011.1| 420|Homo sapiens cytochrome P450 subfami... 36 0.23
AF280109-1|AAG33010.1| 504|Homo sapiens cytochrome P450 subfami... 36 0.23
AF280108-1|AAG33009.1| 503|Homo sapiens cytochrome P450 subfami... 36 0.23
AF280107-1|AAG32291.1| 106|Homo sapiens cytochrome P450 polypep... 36 0.23
AC011904-5|AAS07394.1| 504|Homo sapiens unknown protein. 36 0.23
AC011904-4|AAS07395.1| 503|Homo sapiens unknown protein. 36 0.23
M63871-1|AAA59984.1| 508|Homo sapiens CYP17 protein. 34 0.52
M19489-1|AAA36405.1| 508|Homo sapiens CYP17 protein. 34 0.52
M31153-1|AAA52140.1| 508|Homo sapiens CYP17 protein. 34 0.69
M14564-1|AAA52151.1| 508|Homo sapiens CYP17 protein. 34 0.69
DQ530598-1|ABF50972.1| 508|Homo sapiens cytochrome P450, family... 34 0.69
BT020000-1|AAV38803.1| 508|Homo sapiens cytochrome P450, family... 34 0.69
BC063388-1|AAH63388.1| 508|Homo sapiens cytochrome P450, family... 34 0.69
BC062997-1|AAH62997.1| 508|Homo sapiens cytochrome P450, family... 34 0.69
AL358790-3|CAI52498.1| 508|Homo sapiens cytochrome P450, family... 34 0.69
X56452-1|CAA39833.1| 56|Homo sapiens unspecific monooxygenase ... 31 3.7
AF081569-1|AAD25924.1| 52|Homo sapiens cytochrome P450 protein. 31 3.7
EF122244-1|ABO41979.1| 216|Homo sapiens cytochrome P450 2F1 var... 30 8.5
AL512656-1|CAI15290.1| 488|Homo sapiens annexin A7 protein. 30 8.5
AL353731-3|CAI52484.1| 488|Homo sapiens annexin A7 protein. 30 8.5
>BC067430-1|AAH67430.1| 491|Homo sapiens cytochrome P450, family 2,
subfamily B, polypeptide 6 protein.
Length = 491
Score = 83.0 bits (196), Expect = 1e-15
Identities = 78/252 (30%), Positives = 120/252 (47%), Gaps = 39/252 (15%)
Frame = +2
Query: 125 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIR 304
PPGP PLP++GNLL + R+ + + +KYG++ + LG VV++ G+E IR
Sbjct: 31 PPGPRPLPLLGNLLQM---DRRGLLKSFL--RFREKYGDVFTVHLGPRPVVMLCGVEAIR 85
Query: 305 E--VSNREVFEGRP-----DGFFY---------------------TMRSFG-------KK 379
E V E F GR D FF TMR FG ++
Sbjct: 86 EALVDKAEAFSGRGKIAMVDPFFRGYGVIFANGNRWKVLRRFSVTTMRDFGMGKRSVEER 145
Query: 380 LGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKLCSLVMRL 559
+ EE + L++ G + +FH NI+ +V GKR+ +DQ K+ +L +
Sbjct: 146 IQEEAQCLIEELRKSKGALMDPTFLFHSITANIICSIVFGKRFHYQDQEFLKMLNLFYQT 205
Query: 560 FKLVDMSGGIL--NFLPFLRHF--VPRLIGFTELQEIHNALHQYLREIIKEHQXNLQLGA 727
F L+ G L F FL++F R + + LQEI NA Y+ +++H+ L A
Sbjct: 206 FSLISSVFGQLFELFSGFLKYFPGAHRQV-YKNLQEI-NA---YIGHSVEKHRETLDPSA 260
Query: 728 PKDVIDAFLIDM 763
P+D+ID +L+ M
Sbjct: 261 PRDLIDTYLLHM 272
>BC067431-1|AAH67431.1| 491|Homo sapiens cytochrome P450, family 2,
subfamily B, polypeptide 6 protein.
Length = 491
Score = 81.4 bits (192), Expect = 3e-15
Identities = 79/258 (30%), Positives = 121/258 (46%), Gaps = 39/258 (15%)
Frame = +2
Query: 125 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIR 304
PPGP PLP++GNLL + R+ + + +KYG++ + LG VV++ G+E IR
Sbjct: 31 PPGPRPLPLLGNLLQM---DRRGLLKSFL--RFREKYGDVFTVHLGPRPVVMLCGVEAIR 85
Query: 305 E--VSNREVFEGRP-----DGFFY---------------------TMRSFG-------KK 379
E V E F GR D FF TMR FG ++
Sbjct: 86 EALVDKAEAFSGRGKIAMVDPFFRGYGVIFANGNRWKVLRRFSVTTMRDFGMGKRSVEER 145
Query: 380 LGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKLCSLVMRL 559
+ EE + L++ G + +F NI+ +V GKR+ +DQ K+ +L +
Sbjct: 146 IQEEAQCLIEELRKSKGALMDPTFLFQSITANIICSIVFGKRFHYQDQEFLKMLNLFYQT 205
Query: 560 FKLVDMSGGIL--NFLPFLRHF--VPRLIGFTELQEIHNALHQYLREIIKEHQXNLQLGA 727
F L+ G L F FL +F R + + LQEI NA Y+ +++H+ L A
Sbjct: 206 FSLISSVFGQLFELFSGFLTYFPGAHRQV-YKNLQEI-NA---YIGHSVEKHRETLDPSA 260
Query: 728 PKDVIDAFLIDMLESQXD 781
PKD+ID +L+ M E + +
Sbjct: 261 PKDLIDTYLLHMEEEKSN 278
>M29874-1|AAA52144.1| 491|Homo sapiens CYP2B protein.
Length = 491
Score = 81.0 bits (191), Expect = 5e-15
Identities = 78/252 (30%), Positives = 119/252 (47%), Gaps = 39/252 (15%)
Frame = +2
Query: 125 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIR 304
PPGP PLP++GNLL + R+ + + +KYG++ + LG VV++ G+E IR
Sbjct: 31 PPGPRPLPLLGNLLQM---DRRGLLKSFL--RFREKYGDVFTVHLGPRPVVMLCGVEAIR 85
Query: 305 E--VSNREVFEGRP-----DGFFY---------------------TMRSFG-------KK 379
E V E F GR D FF TMR FG ++
Sbjct: 86 EALVDKAEAFSGRGKIAMVDPFFRGYGVIFANGNRWKVLRRFSVTTMRDFGMGKRSVEER 145
Query: 380 LGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKLCSLVMRL 559
+ EE + L++ G + +F NI+ +V GKR+ +DQ K+ +L +
Sbjct: 146 IQEEAQCLIEELRKSKGALMDPTFLFQSITANIICSIVFGKRFHYQDQEFLKMLNLFYQT 205
Query: 560 FKLVDMSGGIL--NFLPFLRHF--VPRLIGFTELQEIHNALHQYLREIIKEHQXNLQLGA 727
F L+ G L F FL++F R + + LQEI NA Y+ +++H+ L A
Sbjct: 206 FSLISSVFGQLFELFSGFLKYFPGAHRQV-YKNLQEI-NA---YIGHSVEKHRETLDPSA 260
Query: 728 PKDVIDAFLIDM 763
PKD+ID +L+ M
Sbjct: 261 PKDLIDTYLLHM 272
>DQ298753-1|ABB84469.1| 491|Homo sapiens cytochrome P450, family 2,
subfamily B, polypeptide 6 protein.
Length = 491
Score = 81.0 bits (191), Expect = 5e-15
Identities = 78/252 (30%), Positives = 119/252 (47%), Gaps = 39/252 (15%)
Frame = +2
Query: 125 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIR 304
PPGP PLP++GNLL + R+ + + +KYG++ + LG VV++ G+E IR
Sbjct: 31 PPGPRPLPLLGNLLQM---DRRGLLKSFL--RFREKYGDVFTVHLGPRPVVMLCGVEAIR 85
Query: 305 E--VSNREVFEGRP-----DGFFY---------------------TMRSFG-------KK 379
E V E F GR D FF TMR FG ++
Sbjct: 86 EALVDKAEAFSGRGKIAMVDPFFRGYGVIFANGNRWKVLRRFSVTTMRDFGMGKRSVEER 145
Query: 380 LGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKLCSLVMRL 559
+ EE + L++ G + +F NI+ +V GKR+ +DQ K+ +L +
Sbjct: 146 IQEEAQCLIEELRKSKGALMDPTFLFQSITANIICSIVFGKRFHYQDQEFLKMLNLFYQT 205
Query: 560 FKLVDMSGGIL--NFLPFLRHF--VPRLIGFTELQEIHNALHQYLREIIKEHQXNLQLGA 727
F L+ G L F FL++F R + + LQEI NA Y+ +++H+ L A
Sbjct: 206 FSLISSVFGQLFELFSGFLKYFPGAHRQV-YKNLQEI-NA---YIGHSVEKHRETLDPSA 260
Query: 728 PKDVIDAFLIDM 763
PKD+ID +L+ M
Sbjct: 261 PKDLIDTYLLHM 272
>AC023172-1|AAF32444.1| 491|Homo sapiens CYP2B6 protein.
Length = 491
Score = 81.0 bits (191), Expect = 5e-15
Identities = 78/252 (30%), Positives = 119/252 (47%), Gaps = 39/252 (15%)
Frame = +2
Query: 125 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIR 304
PPGP PLP++GNLL + R+ + + +KYG++ + LG VV++ G+E IR
Sbjct: 31 PPGPRPLPLLGNLLQM---DRRGLLKSFL--RFREKYGDVFTVHLGPRPVVMLCGVEAIR 85
Query: 305 E--VSNREVFEGRP-----DGFFY---------------------TMRSFG-------KK 379
E V E F GR D FF TMR FG ++
Sbjct: 86 EALVDKAEAFSGRGKIAMVDPFFRGYGVIFANGNRWKVLRRFSVTTMRDFGMGKRSVEER 145
Query: 380 LGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKLCSLVMRL 559
+ EE + L++ G + +F NI+ +V GKR+ +DQ K+ +L +
Sbjct: 146 IQEEAQCLIEELRKSKGALMDPTFLFQSITANIICSIVFGKRFHYQDQEFLKMLNLFYQT 205
Query: 560 FKLVDMSGGIL--NFLPFLRHF--VPRLIGFTELQEIHNALHQYLREIIKEHQXNLQLGA 727
F L+ G L F FL++F R + + LQEI NA Y+ +++H+ L A
Sbjct: 206 FSLISSVFGQLFELFSGFLKYFPGAHRQV-YKNLQEI-NA---YIGHSVEKHRETLDPSA 260
Query: 728 PKDVIDAFLIDM 763
PKD+ID +L+ M
Sbjct: 261 PKDLIDTYLLHM 272
>AF182277-1|AAF13602.1| 491|Homo sapiens cytochrome P450-2B6
protein.
Length = 491
Score = 80.2 bits (189), Expect = 8e-15
Identities = 71/250 (28%), Positives = 115/250 (46%), Gaps = 37/250 (14%)
Frame = +2
Query: 125 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIR 304
PPGP PLP++GNLL + R+ + + +KYG++ + LG VV++ G+E IR
Sbjct: 31 PPGPRPLPLLGNLLQM---DRRGLLKSFL--RFREKYGDVFTVHLGPRPVVMLCGVEAIR 85
Query: 305 E--VSNREVFEGRP-----DGFFY---------------------TMRSFG-------KK 379
E V E F GR D FF TMR FG ++
Sbjct: 86 EALVDKAEAFSGRGKIAMVDPFFRGYGVIFANGNRWKVLRRFSVTTMRDFGMGKRSVEER 145
Query: 380 LGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKLCSLVMRL 559
EE + L++ G + +FH NI+ +V GKR+ +DQ K+ +L +
Sbjct: 146 TQEEAQCLIEELRKSKGALMDATFLFHSITANIICSIVFGKRFHYQDQEFLKMLNLFYQT 205
Query: 560 FKLVDMSGGIL--NFLPFLRHFVPRLIGFTELQEIHNALHQYLREIIKEHQXNLQLGAPK 733
F L+ G L F FL++F ++ + ++ Y+ +++H+ L AP+
Sbjct: 206 FSLISSVFGQLFELFSGFLKYFPG---AHRQVYKNPQEINAYIGHSVEKHRETLDPSAPR 262
Query: 734 DVIDAFLIDM 763
D+ID +L+ M
Sbjct: 263 DLIDTYLLHM 272
>AY220845-1|AAO49806.1| 516|Homo sapiens cytochrome P450 protein.
Length = 516
Score = 49.6 bits (113), Expect(2) = 1e-13
Identities = 30/88 (34%), Positives = 48/88 (54%), Gaps = 2/88 (2%)
Frame = +2
Query: 122 YPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELI 301
YPPGP PLP +GNLL V +++ + C + +++G++ L+L VVV+ G+ +
Sbjct: 33 YPPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFNLQLAWTPVVVLNGLAAV 87
Query: 302 RE--VSNREVFEGRPDGFFYTMRSFGKK 379
RE V+ E RP Y + FG +
Sbjct: 88 REAMVTRGEDTADRPPAPIYQVLGFGPR 115
Score = 47.2 bits (107), Expect(2) = 1e-13
Identities = 37/135 (27%), Positives = 61/135 (45%), Gaps = 4/135 (2%)
Frame = +2
Query: 362 RSFGKKLGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKLC 541
+S + + EE L AG P N + + N++ L G+R++ +D R +L
Sbjct: 147 KSLEQWVTEEAACLCAAFADQAGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLL 206
Query: 542 SLVMRLFKLVDMSG---GILNFLPFLRHFVPRLIGFTELQEIHNALHQYLREIIKEHQXN 712
L K + SG +LN +P L H +P L G ++ A L E++ EH+
Sbjct: 207 DLAQEGLK--EESGFLREVLNAVPVLPH-IPALAG--KVLRFQKAFLTQLDELLTEHRMT 261
Query: 713 LQ-LGAPKDVIDAFL 754
P+D+ +AFL
Sbjct: 262 WDPAQPPRDLTEAFL 276
>BC104909-1|AAI04910.1| 501|Homo sapiens cytochrome P450, family 2,
subfamily R, polypeptide 1 protein.
Length = 501
Score = 57.2 bits (132), Expect(2) = 3e-13
Identities = 29/82 (35%), Positives = 47/82 (57%), Gaps = 2/82 (2%)
Frame = +2
Query: 101 RRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 280
++ R + +PPGP LP +GN+ S+ S + H+ + SQ YG + L LG I+ VV
Sbjct: 32 KQRRPMGFPPGPPGLPFIGNIYSLAASS---ELPHVYMRKQSQVYGEIFSLDLGGISTVV 88
Query: 281 VTGIELIRE--VSNREVFEGRP 340
+ G ++++E V E+F RP
Sbjct: 89 LNGYDVVKECLVHQSEIFADRP 110
Score = 37.9 bits (84), Expect(2) = 3e-13
Identities = 34/149 (22%), Positives = 67/149 (44%), Gaps = 4/149 (2%)
Frame = +2
Query: 347 FFYTMRSFGKKLGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQR 526
F Y +SF K+ EE + G P Q+ + NI ++ G+R+ ED
Sbjct: 147 FGYGQKSFESKILEETKFFNDAIETYKGRPFDFKQLITNAVSNITNLIIFGERFTYEDTD 206
Query: 527 LKKLCSLVMRLFKLVDMSGGIL-NFLPFLRHFVPRLIGFTELQEI-HNA--LHQYLREII 694
+ + L +L + L N P++ ++ F + Q++ NA ++ +L +I
Sbjct: 207 FQHMIELFSENVELAASASVFLYNAFPWI-----GILPFGKHQQLFRNAAVVYDFLSRLI 261
Query: 695 KEHQXNLQLGAPKDVIDAFLIDMLESQXD 781
++ N + P+ +DA+L +M + + D
Sbjct: 262 EKASVNRKPQLPQHFVDAYLDEMDQGKND 290
>BC104907-1|AAI04908.1| 501|Homo sapiens cytochrome P450, family 2,
subfamily R, polypeptide 1 protein.
Length = 501
Score = 57.2 bits (132), Expect(2) = 3e-13
Identities = 29/82 (35%), Positives = 47/82 (57%), Gaps = 2/82 (2%)
Frame = +2
Query: 101 RRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 280
++ R + +PPGP LP +GN+ S+ S + H+ + SQ YG + L LG I+ VV
Sbjct: 32 KQRRPMGFPPGPPGLPFIGNIYSLAASS---ELPHVYMRKQSQVYGEIFSLDLGGISTVV 88
Query: 281 VTGIELIRE--VSNREVFEGRP 340
+ G ++++E V E+F RP
Sbjct: 89 LNGYDVVKECLVHQSEIFADRP 110
Score = 37.9 bits (84), Expect(2) = 3e-13
Identities = 34/149 (22%), Positives = 67/149 (44%), Gaps = 4/149 (2%)
Frame = +2
Query: 347 FFYTMRSFGKKLGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQR 526
F Y +SF K+ EE + G P Q+ + NI ++ G+R+ ED
Sbjct: 147 FGYGQKSFESKILEETKFFNDAIETYKGRPFDFKQLITNAVSNITNLIIFGERFTYEDTD 206
Query: 527 LKKLCSLVMRLFKLVDMSGGIL-NFLPFLRHFVPRLIGFTELQEI-HNA--LHQYLREII 694
+ + L +L + L N P++ ++ F + Q++ NA ++ +L +I
Sbjct: 207 FQHMIELFSENVELAASASVFLYNAFPWI-----GILPFGKHQQLFRNAAVVYDFLSRLI 261
Query: 695 KEHQXNLQLGAPKDVIDAFLIDMLESQXD 781
++ N + P+ +DA+L +M + + D
Sbjct: 262 EKASVNRKPQLPQHFVDAYLDEMDQGKND 290
>AY323817-1|AAQ23114.1| 501|Homo sapiens cytochrome P450 2R1
protein.
Length = 501
Score = 57.2 bits (132), Expect(2) = 3e-13
Identities = 29/82 (35%), Positives = 47/82 (57%), Gaps = 2/82 (2%)
Frame = +2
Query: 101 RRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 280
++ R + +PPGP LP +GN+ S+ S + H+ + SQ YG + L LG I+ VV
Sbjct: 32 KQRRPMGFPPGPPGLPFIGNIYSLAASS---ELPHVYMRKQSQVYGEIFSLDLGGISTVV 88
Query: 281 VTGIELIRE--VSNREVFEGRP 340
+ G ++++E V E+F RP
Sbjct: 89 LNGYDVVKECLVHQSEIFADRP 110
Score = 37.9 bits (84), Expect(2) = 3e-13
Identities = 34/149 (22%), Positives = 67/149 (44%), Gaps = 4/149 (2%)
Frame = +2
Query: 347 FFYTMRSFGKKLGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQR 526
F Y +SF K+ EE + G P Q+ + NI ++ G+R+ ED
Sbjct: 147 FGYGQKSFESKILEETKFFNDAIETYKGRPFDFKQLITNAVSNITNLIIFGERFTYEDTD 206
Query: 527 LKKLCSLVMRLFKLVDMSGGIL-NFLPFLRHFVPRLIGFTELQEI-HNA--LHQYLREII 694
+ + L +L + L N P++ ++ F + Q++ NA ++ +L +I
Sbjct: 207 FQHMIELFSENVELAASASVFLYNAFPWI-----GILPFGKHQQLFRNAAVVYDFLSRLI 261
Query: 695 KEHQXNLQLGAPKDVIDAFLIDMLESQXD 781
++ N + P+ +DA+L +M + + D
Sbjct: 262 EKASVNRKPQLPQHFVDAYLDEMDQGKND 290
>BC132767-1|AAI32768.1| 544|Homo sapiens cytochrome P450, family 2,
subfamily U, polypeptide 1 protein.
Length = 544
Score = 56.8 bits (131), Expect(2) = 4e-13
Identities = 44/148 (29%), Positives = 76/148 (51%), Gaps = 8/148 (5%)
Frame = +2
Query: 356 TMRSFGK-KLGEECEALVQLRLADA-----GE-PILVNQMFHITIVNILWRLVAGKRYDL 514
T+R FG KL E + + + + A GE P + + NI+ L G+R+D
Sbjct: 184 TLRHFGLGKLSLEPKIIEEFKYVKAEMQKHGEDPFCPFSIISNAVSNIICSLCFGQRFDY 243
Query: 515 EDQRLKKLCSLVMRLFKLVDMSGGIL-NFLPFLRHFVPRLIGFTELQEIHNALHQYLREI 691
+ KK+ + R ++ S +L N P+L +++P F EL++I + +L++I
Sbjct: 244 TNSEFKKMLGFMSRGLEICLNSQVLLVNICPWL-YYLP-FGPFKELRQIEKDITSFLKKI 301
Query: 692 IKEHQXNLQLGAPKDVIDAFLIDMLESQ 775
IK+HQ +L P+D ID +L+ M E +
Sbjct: 302 IKDHQESLDRENPQDFIDMYLLHMEEER 329
Score = 37.9 bits (84), Expect(2) = 4e-13
Identities = 31/100 (31%), Positives = 44/100 (44%), Gaps = 20/100 (20%)
Frame = +2
Query: 101 RRHRGLCYPPGPTPLPIVGNLLSVL---------WESRKFKC---------HHLIWQSWS 226
RR R PPGPTP P+VGN VL W S + + ++ +
Sbjct: 52 RRRRARGIPPGPTPWPLVGNFGHVLLPPFLRRRSWLSSRTRAAGIDPSVIGPQVLLAHLA 111
Query: 227 QKYGNLLGLRLGSINVVVVTGIELIRE--VSNREVFEGRP 340
+ YG++ +G VVV++ +RE V EVF RP
Sbjct: 112 RVYGSIFSFFIGHYLVVVLSDFHSVREALVQQAEVFSDRP 151
>AY343323-1|AAQ21380.1| 544|Homo sapiens cytochrome P450 protein.
Length = 544
Score = 56.8 bits (131), Expect(2) = 4e-13
Identities = 44/148 (29%), Positives = 76/148 (51%), Gaps = 8/148 (5%)
Frame = +2
Query: 356 TMRSFGK-KLGEECEALVQLRLADA-----GE-PILVNQMFHITIVNILWRLVAGKRYDL 514
T+R FG KL E + + + + A GE P + + NI+ L G+R+D
Sbjct: 184 TLRHFGLGKLSLEPKIIEEFKYVKAEMQKHGEDPFCPFSIISNAVSNIICSLCFGQRFDY 243
Query: 515 EDQRLKKLCSLVMRLFKLVDMSGGIL-NFLPFLRHFVPRLIGFTELQEIHNALHQYLREI 691
+ KK+ + R ++ S +L N P+L +++P F EL++I + +L++I
Sbjct: 244 TNSEFKKMLGFMSRGLEICLNSQVLLVNICPWL-YYLP-FGPFKELRQIEKDITSFLKKI 301
Query: 692 IKEHQXNLQLGAPKDVIDAFLIDMLESQ 775
IK+HQ +L P+D ID +L+ M E +
Sbjct: 302 IKDHQESLDRENPQDFIDMYLLHMEEER 329
Score = 37.9 bits (84), Expect(2) = 4e-13
Identities = 31/100 (31%), Positives = 44/100 (44%), Gaps = 20/100 (20%)
Frame = +2
Query: 101 RRHRGLCYPPGPTPLPIVGNLLSVL---------WESRKFKC---------HHLIWQSWS 226
RR R PPGPTP P+VGN VL W S + + ++ +
Sbjct: 52 RRRRARGIPPGPTPWPLVGNFGHVLLPPFLRRRSWLSSRTRAAGIDPSVIGPQVLLAHLA 111
Query: 227 QKYGNLLGLRLGSINVVVVTGIELIRE--VSNREVFEGRP 340
+ YG++ +G VVV++ +RE V EVF RP
Sbjct: 112 RVYGSIFSFFIGHYLVVVLSDFHSVREALVQQAEVFSDRP 151
>DQ282158-1|ABB77906.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 48.0 bits (109), Expect(2) = 7e-13
Identities = 37/138 (26%), Positives = 63/138 (45%), Gaps = 4/138 (2%)
Frame = +2
Query: 362 RSFGKKLGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKLC 541
+S + + EE L +G P N + + N++ L G+R++ +D R +L
Sbjct: 147 KSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLL 206
Query: 542 SLVMRLFKLVDMSG---GILNFLPFLRHFVPRLIGFTELQEIHNALHQYLREIIKEHQXN 712
L K + SG +LN +P L H +P L G ++ A L E++ EH+
Sbjct: 207 DLAQEGLK--EESGFLREVLNAVPVLLH-IPALAG--KVLRFQKAFLTQLDELLTEHRMT 261
Query: 713 LQ-LGAPKDVIDAFLIDM 763
P+D+ +AFL +M
Sbjct: 262 WDPAQPPRDLTEAFLAEM 279
Score = 46.0 bits (104), Expect(2) = 7e-13
Identities = 32/96 (33%), Positives = 51/96 (53%), Gaps = 3/96 (3%)
Frame = +2
Query: 101 RRHRGLC-YPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVV 277
RR R YPPGP PLP +GNLL V +++ + C + +++G++ L+L VV
Sbjct: 25 RRQRWAARYPPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWTPVV 79
Query: 278 VVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKK 379
V+ G+ +RE V++ E RP + FG +
Sbjct: 80 VLNGLAAVREALVTHGEDTADRPPVPIIQILGFGPR 115
>DQ282157-1|ABB77905.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 48.0 bits (109), Expect(2) = 7e-13
Identities = 37/138 (26%), Positives = 63/138 (45%), Gaps = 4/138 (2%)
Frame = +2
Query: 362 RSFGKKLGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKLC 541
+S + + EE L +G P N + + N++ L G+R++ +D R +L
Sbjct: 147 KSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLL 206
Query: 542 SLVMRLFKLVDMSG---GILNFLPFLRHFVPRLIGFTELQEIHNALHQYLREIIKEHQXN 712
L K + SG +LN +P L H +P L G ++ A L E++ EH+
Sbjct: 207 DLAQEGLK--EESGFLREVLNAVPVLLH-IPALAG--KVLRFQKAFLTQLDELLTEHRMT 261
Query: 713 LQ-LGAPKDVIDAFLIDM 763
P+D+ +AFL +M
Sbjct: 262 WDPAQPPRDLTEAFLAEM 279
Score = 46.0 bits (104), Expect(2) = 7e-13
Identities = 32/96 (33%), Positives = 51/96 (53%), Gaps = 3/96 (3%)
Frame = +2
Query: 101 RRHRGLC-YPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVV 277
RR R YPPGP PLP +GNLL V +++ + C + +++G++ L+L VV
Sbjct: 25 RRQRWAARYPPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWTPVV 79
Query: 278 VVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKK 379
V+ G+ +RE V++ E RP + FG +
Sbjct: 80 VLNGLAAVREALVTHGEDTADRPPVPIIQILGFGPR 115
>X08006-1|CAA30807.1| 497|Homo sapiens cytochrome P450 db1 protein.
Length = 497
Score = 48.0 bits (109), Expect(2) = 9e-13
Identities = 37/138 (26%), Positives = 63/138 (45%), Gaps = 4/138 (2%)
Frame = +2
Query: 362 RSFGKKLGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKLC 541
+S + + EE L +G P N + + N++ L G+R++ +D R +L
Sbjct: 147 KSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLL 206
Query: 542 SLVMRLFKLVDMSG---GILNFLPFLRHFVPRLIGFTELQEIHNALHQYLREIIKEHQXN 712
L K + SG +LN +P L H +P L G ++ A L E++ EH+
Sbjct: 207 DLAQEGLK--EESGFLREVLNAVPVLLH-IPALAG--KVLRFQKAFLTQLDELLTEHRMT 261
Query: 713 LQ-LGAPKDVIDAFLIDM 763
P+D+ +AFL +M
Sbjct: 262 WDPAQPPRDLTEAFLAEM 279
Score = 45.6 bits (103), Expect(2) = 9e-13
Identities = 32/96 (33%), Positives = 51/96 (53%), Gaps = 3/96 (3%)
Frame = +2
Query: 101 RRHRGLC-YPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVV 277
RR R YPPGP PLP +GNLL V +++ + C + +++G++ L+L VV
Sbjct: 25 RRQRWAARYPPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWTPVV 79
Query: 278 VVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKK 379
V+ G+ +RE V++ E RP + FG +
Sbjct: 80 VLNGLAAVREALVTHGEDTADRPPVPITQILGFGPR 115
>M33388-1|AAA53500.1| 497|Homo sapiens cytochrome P450 IID6
protein.
Length = 497
Score = 48.0 bits (109), Expect(2) = 9e-13
Identities = 37/138 (26%), Positives = 63/138 (45%), Gaps = 4/138 (2%)
Frame = +2
Query: 362 RSFGKKLGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKLC 541
+S + + EE L +G P N + + N++ L G+R++ +D R +L
Sbjct: 147 KSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLL 206
Query: 542 SLVMRLFKLVDMSG---GILNFLPFLRHFVPRLIGFTELQEIHNALHQYLREIIKEHQXN 712
L K + SG +LN +P L H +P L G ++ A L E++ EH+
Sbjct: 207 DLAQEGLK--EESGFLREVLNAVPVLLH-IPALAG--KVLRFQKAFLTQLDELLTEHRMT 261
Query: 713 LQ-LGAPKDVIDAFLIDM 763
P+D+ +AFL +M
Sbjct: 262 WDPAQPPRDLTEAFLAEM 279
Score = 45.6 bits (103), Expect(2) = 9e-13
Identities = 32/96 (33%), Positives = 51/96 (53%), Gaps = 3/96 (3%)
Frame = +2
Query: 101 RRHRGLC-YPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVV 277
RR R YPPGP PLP +GNLL V +++ + C + +++G++ L+L VV
Sbjct: 25 RRQRWAARYPPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWTPVV 79
Query: 278 VVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKK 379
V+ G+ +RE V++ E RP + FG +
Sbjct: 80 VLNGLAAVREALVTHGEDTADRPPVPITQILGFGPR 115
>M20403-1|AAA52153.1| 497|Homo sapiens CYP2D protein.
Length = 497
Score = 48.0 bits (109), Expect(2) = 9e-13
Identities = 37/138 (26%), Positives = 63/138 (45%), Gaps = 4/138 (2%)
Frame = +2
Query: 362 RSFGKKLGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKLC 541
+S + + EE L +G P N + + N++ L G+R++ +D R +L
Sbjct: 147 KSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLL 206
Query: 542 SLVMRLFKLVDMSG---GILNFLPFLRHFVPRLIGFTELQEIHNALHQYLREIIKEHQXN 712
L K + SG +LN +P L H +P L G ++ A L E++ EH+
Sbjct: 207 DLAQEGLK--EESGFLREVLNAVPVLLH-IPALAG--KVLRFQKAFLTQLDELLTEHRMT 261
Query: 713 LQ-LGAPKDVIDAFLIDM 763
P+D+ +AFL +M
Sbjct: 262 WDPAQPPRDLTEAFLAEM 279
Score = 45.6 bits (103), Expect(2) = 9e-13
Identities = 32/96 (33%), Positives = 51/96 (53%), Gaps = 3/96 (3%)
Frame = +2
Query: 101 RRHRGLC-YPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVV 277
RR R YPPGP PLP +GNLL V +++ + C + +++G++ L+L VV
Sbjct: 25 RRQRWAARYPPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWTPVV 79
Query: 278 VVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKK 379
V+ G+ +RE V++ E RP + FG +
Sbjct: 80 VLNGLAAVREALVTHGEDTADRPPVPITQILGFGPR 115
>DQ282160-1|ABB77908.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 48.0 bits (109), Expect(2) = 9e-13
Identities = 37/138 (26%), Positives = 63/138 (45%), Gaps = 4/138 (2%)
Frame = +2
Query: 362 RSFGKKLGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKLC 541
+S + + EE L +G P N + + N++ L G+R++ +D R +L
Sbjct: 147 KSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLL 206
Query: 542 SLVMRLFKLVDMSG---GILNFLPFLRHFVPRLIGFTELQEIHNALHQYLREIIKEHQXN 712
L K + SG +LN +P L H +P L G ++ A L E++ EH+
Sbjct: 207 DLAQEGLK--EESGFLREVLNAVPVLLH-IPALAG--KVLRFQKAFLTQLDELLTEHRMT 261
Query: 713 LQ-LGAPKDVIDAFLIDM 763
P+D+ +AFL +M
Sbjct: 262 WDPAQPPRDLTEAFLAEM 279
Score = 45.6 bits (103), Expect(2) = 9e-13
Identities = 32/96 (33%), Positives = 51/96 (53%), Gaps = 3/96 (3%)
Frame = +2
Query: 101 RRHRGLC-YPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVV 277
RR R YPPGP PLP +GNLL V +++ + C + +++G++ L+L VV
Sbjct: 25 RRQRWAARYPPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWTPVV 79
Query: 278 VVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKK 379
V+ G+ +RE V++ E RP + FG +
Sbjct: 80 VLNGLAAVREALVTHGEDTADRPPVPITQILGFGPR 115
>DQ282159-1|ABB77907.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 48.0 bits (109), Expect(2) = 9e-13
Identities = 37/138 (26%), Positives = 63/138 (45%), Gaps = 4/138 (2%)
Frame = +2
Query: 362 RSFGKKLGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKLC 541
+S + + EE L +G P N + + N++ L G+R++ +D R +L
Sbjct: 147 KSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLL 206
Query: 542 SLVMRLFKLVDMSG---GILNFLPFLRHFVPRLIGFTELQEIHNALHQYLREIIKEHQXN 712
L K + SG +LN +P L H +P L G ++ A L E++ EH+
Sbjct: 207 DLAQEGLK--EESGFLREVLNAVPVLLH-IPALAG--KVLRFQKAFLTQLDELLTEHRMT 261
Query: 713 LQ-LGAPKDVIDAFLIDM 763
P+D+ +AFL +M
Sbjct: 262 WDPAQPPRDLTEAFLAEM 279
Score = 45.6 bits (103), Expect(2) = 9e-13
Identities = 32/96 (33%), Positives = 51/96 (53%), Gaps = 3/96 (3%)
Frame = +2
Query: 101 RRHRGLC-YPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVV 277
RR R YPPGP PLP +GNLL V +++ + C + +++G++ L+L VV
Sbjct: 25 RRQRWAARYPPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWTPVV 79
Query: 278 VVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKK 379
V+ G+ +RE V++ E RP + FG +
Sbjct: 80 VLNGLAAVREALVTHGEDTADRPPVPITQILGFGPR 115
>DQ282156-1|ABB77904.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 48.0 bits (109), Expect(2) = 9e-13
Identities = 37/138 (26%), Positives = 63/138 (45%), Gaps = 4/138 (2%)
Frame = +2
Query: 362 RSFGKKLGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKLC 541
+S + + EE L +G P N + + N++ L G+R++ +D R +L
Sbjct: 147 KSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLL 206
Query: 542 SLVMRLFKLVDMSG---GILNFLPFLRHFVPRLIGFTELQEIHNALHQYLREIIKEHQXN 712
L K + SG +LN +P L H +P L G ++ A L E++ EH+
Sbjct: 207 DLAQEGLK--EESGFLREVLNAVPVLLH-IPALAG--KVLRFQKAFLTQLDELLTEHRMT 261
Query: 713 LQ-LGAPKDVIDAFLIDM 763
P+D+ +AFL +M
Sbjct: 262 WDPAQPPRDLTEAFLAEM 279
Score = 45.6 bits (103), Expect(2) = 9e-13
Identities = 32/96 (33%), Positives = 51/96 (53%), Gaps = 3/96 (3%)
Frame = +2
Query: 101 RRHRGLC-YPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVV 277
RR R YPPGP PLP +GNLL V +++ + C + +++G++ L+L VV
Sbjct: 25 RRQRWAARYPPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWTPVV 79
Query: 278 VVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKK 379
V+ G+ +RE V++ E RP + FG +
Sbjct: 80 VLNGLAAVREALVTHGEDTADRPPVPITQILGFGPR 115
>DQ282153-1|ABB77901.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 48.0 bits (109), Expect(2) = 9e-13
Identities = 37/138 (26%), Positives = 63/138 (45%), Gaps = 4/138 (2%)
Frame = +2
Query: 362 RSFGKKLGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKLC 541
+S + + EE L +G P N + + N++ L G+R++ +D R +L
Sbjct: 147 KSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLL 206
Query: 542 SLVMRLFKLVDMSG---GILNFLPFLRHFVPRLIGFTELQEIHNALHQYLREIIKEHQXN 712
L K + SG +LN +P L H +P L G ++ A L E++ EH+
Sbjct: 207 DLAQEGLK--EESGFLREVLNAVPVLLH-IPALAG--KVLRFQKAFLTQLDELLTEHRMT 261
Query: 713 LQ-LGAPKDVIDAFLIDM 763
P+D+ +AFL +M
Sbjct: 262 WDPAQPPRDLTEAFLAEM 279
Score = 45.6 bits (103), Expect(2) = 9e-13
Identities = 32/96 (33%), Positives = 51/96 (53%), Gaps = 3/96 (3%)
Frame = +2
Query: 101 RRHRGLC-YPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVV 277
RR R YPPGP PLP +GNLL V +++ + C + +++G++ L+L VV
Sbjct: 25 RRQRWAARYPPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWTPVV 79
Query: 278 VVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKK 379
V+ G+ +RE V++ E RP + FG +
Sbjct: 80 VLNGLAAVREALVTHGEDTADRPPVPITQILGFGPR 115
>DQ282147-1|ABB77898.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 48.0 bits (109), Expect(2) = 9e-13
Identities = 37/138 (26%), Positives = 63/138 (45%), Gaps = 4/138 (2%)
Frame = +2
Query: 362 RSFGKKLGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKLC 541
+S + + EE L +G P N + + N++ L G+R++ +D R +L
Sbjct: 147 KSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLL 206
Query: 542 SLVMRLFKLVDMSG---GILNFLPFLRHFVPRLIGFTELQEIHNALHQYLREIIKEHQXN 712
L K + SG +LN +P L H +P L G ++ A L E++ EH+
Sbjct: 207 DLAQEGLK--EESGFLREVLNAVPVLLH-IPALAG--KVLRFQKAFLTQLDELLTEHRMT 261
Query: 713 LQ-LGAPKDVIDAFLIDM 763
P+D+ +AFL +M
Sbjct: 262 WDPAQPPRDLTEAFLAEM 279
Score = 45.6 bits (103), Expect(2) = 9e-13
Identities = 32/96 (33%), Positives = 51/96 (53%), Gaps = 3/96 (3%)
Frame = +2
Query: 101 RRHRGLC-YPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVV 277
RR R YPPGP PLP +GNLL V +++ + C + +++G++ L+L VV
Sbjct: 25 RRQRWAARYPPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWTPVV 79
Query: 278 VVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKK 379
V+ G+ +RE V++ E RP + FG +
Sbjct: 80 VLNGLAAVREALVTHGEDTADRPPVPITQILGFGPR 115
>DQ282146-1|ABB77897.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 48.0 bits (109), Expect(2) = 9e-13
Identities = 37/138 (26%), Positives = 63/138 (45%), Gaps = 4/138 (2%)
Frame = +2
Query: 362 RSFGKKLGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKLC 541
+S + + EE L +G P N + + N++ L G+R++ +D R +L
Sbjct: 147 KSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLL 206
Query: 542 SLVMRLFKLVDMSG---GILNFLPFLRHFVPRLIGFTELQEIHNALHQYLREIIKEHQXN 712
L K + SG +LN +P L H +P L G ++ A L E++ EH+
Sbjct: 207 DLAQEGLK--EESGFLREVLNAVPVLLH-IPALAG--KVLRFQKAFLTQLDELLTEHRMT 261
Query: 713 LQ-LGAPKDVIDAFLIDM 763
P+D+ +AFL +M
Sbjct: 262 WDPAQPPRDLTEAFLAEM 279
Score = 45.6 bits (103), Expect(2) = 9e-13
Identities = 32/96 (33%), Positives = 51/96 (53%), Gaps = 3/96 (3%)
Frame = +2
Query: 101 RRHRGLC-YPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVV 277
RR R YPPGP PLP +GNLL V +++ + C + +++G++ L+L VV
Sbjct: 25 RRQRWAARYPPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWTPVV 79
Query: 278 VVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKK 379
V+ G+ +RE V++ E RP + FG +
Sbjct: 80 VLNGLAAVREALVTHGEDTADRPPVPITQILGFGPR 115
>DQ282145-1|ABB77896.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 48.0 bits (109), Expect(2) = 9e-13
Identities = 37/138 (26%), Positives = 63/138 (45%), Gaps = 4/138 (2%)
Frame = +2
Query: 362 RSFGKKLGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKLC 541
+S + + EE L +G P N + + N++ L G+R++ +D R +L
Sbjct: 147 KSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLL 206
Query: 542 SLVMRLFKLVDMSG---GILNFLPFLRHFVPRLIGFTELQEIHNALHQYLREIIKEHQXN 712
L K + SG +LN +P L H +P L G ++ A L E++ EH+
Sbjct: 207 DLAQEGLK--EESGFLREVLNAVPVLLH-IPALAG--KVLRFQKAFLTQLDELLTEHRMT 261
Query: 713 LQ-LGAPKDVIDAFLIDM 763
P+D+ +AFL +M
Sbjct: 262 WDPAQPPRDLTEAFLAEM 279
Score = 45.6 bits (103), Expect(2) = 9e-13
Identities = 32/96 (33%), Positives = 51/96 (53%), Gaps = 3/96 (3%)
Frame = +2
Query: 101 RRHRGLC-YPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVV 277
RR R YPPGP PLP +GNLL V +++ + C + +++G++ L+L VV
Sbjct: 25 RRQRWAARYPPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWTPVV 79
Query: 278 VVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKK 379
V+ G+ +RE V++ E RP + FG +
Sbjct: 80 VLNGLAAVREALVTHGEDTADRPPVPITQILGFGPR 115
>DQ282144-1|ABB77895.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 48.0 bits (109), Expect(2) = 9e-13
Identities = 37/138 (26%), Positives = 63/138 (45%), Gaps = 4/138 (2%)
Frame = +2
Query: 362 RSFGKKLGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKLC 541
+S + + EE L +G P N + + N++ L G+R++ +D R +L
Sbjct: 147 KSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLL 206
Query: 542 SLVMRLFKLVDMSG---GILNFLPFLRHFVPRLIGFTELQEIHNALHQYLREIIKEHQXN 712
L K + SG +LN +P L H +P L G ++ A L E++ EH+
Sbjct: 207 DLAQEGLK--EESGFLREVLNAVPVLLH-IPALAG--KVLRFQKAFLTQLDELLTEHRMT 261
Query: 713 LQ-LGAPKDVIDAFLIDM 763
P+D+ +AFL +M
Sbjct: 262 WDPAQPPRDLTEAFLAEM 279
Score = 45.6 bits (103), Expect(2) = 9e-13
Identities = 32/96 (33%), Positives = 51/96 (53%), Gaps = 3/96 (3%)
Frame = +2
Query: 101 RRHRGLC-YPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVV 277
RR R YPPGP PLP +GNLL V +++ + C + +++G++ L+L VV
Sbjct: 25 RRQRWAARYPPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWTPVV 79
Query: 278 VVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKK 379
V+ G+ +RE V++ E RP + FG +
Sbjct: 80 VLNGLAAVREALVTHGEDTADRPPVPITQILGFGPR 115
>BC126858-1|AAI26859.1| 497|Homo sapiens cytochrome P450, family 2,
subfamily D, polypeptide 6 protein.
Length = 497
Score = 48.0 bits (109), Expect(2) = 9e-13
Identities = 37/138 (26%), Positives = 63/138 (45%), Gaps = 4/138 (2%)
Frame = +2
Query: 362 RSFGKKLGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKLC 541
+S + + EE L +G P N + + N++ L G+R++ +D R +L
Sbjct: 147 KSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLL 206
Query: 542 SLVMRLFKLVDMSG---GILNFLPFLRHFVPRLIGFTELQEIHNALHQYLREIIKEHQXN 712
L K + SG +LN +P L H +P L G ++ A L E++ EH+
Sbjct: 207 DLAQEGLK--EESGFLREVLNAVPVLLH-IPALAG--KVLRFQKAFLTQLDELLTEHRMT 261
Query: 713 LQ-LGAPKDVIDAFLIDM 763
P+D+ +AFL +M
Sbjct: 262 WDPAQPPRDLTEAFLAEM 279
Score = 45.6 bits (103), Expect(2) = 9e-13
Identities = 32/96 (33%), Positives = 51/96 (53%), Gaps = 3/96 (3%)
Frame = +2
Query: 101 RRHRGLC-YPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVV 277
RR R YPPGP PLP +GNLL V +++ + C + +++G++ L+L VV
Sbjct: 25 RRQRWAARYPPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWTPVV 79
Query: 278 VVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKK 379
V+ G+ +RE V++ E RP + FG +
Sbjct: 80 VLNGLAAVREALVTHGEDTADRPPVPITQILGFGPR 115
>BC106758-1|AAI06759.1| 497|Homo sapiens cytochrome P450, family 2,
subfamily D, polypeptide 6 protein.
Length = 497
Score = 48.0 bits (109), Expect(2) = 9e-13
Identities = 37/138 (26%), Positives = 63/138 (45%), Gaps = 4/138 (2%)
Frame = +2
Query: 362 RSFGKKLGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKLC 541
+S + + EE L +G P N + + N++ L G+R++ +D R +L
Sbjct: 147 KSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLL 206
Query: 542 SLVMRLFKLVDMSG---GILNFLPFLRHFVPRLIGFTELQEIHNALHQYLREIIKEHQXN 712
L K + SG +LN +P L H +P L G ++ A L E++ EH+
Sbjct: 207 DLAQEGLK--EESGFLREVLNAVPVLLH-IPALAG--KVLRFQKAFLTQLDELLTEHRMT 261
Query: 713 LQ-LGAPKDVIDAFLIDM 763
P+D+ +AFL +M
Sbjct: 262 WDPAQPPRDLTEAFLAEM 279
Score = 45.6 bits (103), Expect(2) = 9e-13
Identities = 32/96 (33%), Positives = 51/96 (53%), Gaps = 3/96 (3%)
Frame = +2
Query: 101 RRHRGLC-YPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVV 277
RR R YPPGP PLP +GNLL V +++ + C + +++G++ L+L VV
Sbjct: 25 RRQRWAARYPPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWTPVV 79
Query: 278 VVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKK 379
V+ G+ +RE V++ E RP + FG +
Sbjct: 80 VLNGLAAVREALVTHGEDTADRPPVPITQILGFGPR 115
>BC075024-1|AAH75024.1| 497|Homo sapiens cytochrome P450, family 2,
subfamily D, polypeptide 6 protein.
Length = 497
Score = 48.0 bits (109), Expect(2) = 9e-13
Identities = 37/138 (26%), Positives = 63/138 (45%), Gaps = 4/138 (2%)
Frame = +2
Query: 362 RSFGKKLGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKLC 541
+S + + EE L +G P N + + N++ L G+R++ +D R +L
Sbjct: 147 KSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLL 206
Query: 542 SLVMRLFKLVDMSG---GILNFLPFLRHFVPRLIGFTELQEIHNALHQYLREIIKEHQXN 712
L K + SG +LN +P L H +P L G ++ A L E++ EH+
Sbjct: 207 DLAQEGLK--EESGFLREVLNAVPVLLH-IPALAG--KVLRFQKAFLTQLDELLTEHRMT 261
Query: 713 LQ-LGAPKDVIDAFLIDM 763
P+D+ +AFL +M
Sbjct: 262 WDPAQPPRDLTEAFLAEM 279
Score = 45.6 bits (103), Expect(2) = 9e-13
Identities = 32/96 (33%), Positives = 51/96 (53%), Gaps = 3/96 (3%)
Frame = +2
Query: 101 RRHRGLC-YPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVV 277
RR R YPPGP PLP +GNLL V +++ + C + +++G++ L+L VV
Sbjct: 25 RRQRWAARYPPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWTPVV 79
Query: 278 VVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKK 379
V+ G+ +RE V++ E RP + FG +
Sbjct: 80 VLNGLAAVREALVTHGEDTADRPPVPITQILGFGPR 115
>BC075023-1|AAH75023.1| 497|Homo sapiens cytochrome P450, family 2,
subfamily D, polypeptide 6 protein.
Length = 497
Score = 48.0 bits (109), Expect(2) = 9e-13
Identities = 37/138 (26%), Positives = 63/138 (45%), Gaps = 4/138 (2%)
Frame = +2
Query: 362 RSFGKKLGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKLC 541
+S + + EE L +G P N + + N++ L G+R++ +D R +L
Sbjct: 147 KSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLL 206
Query: 542 SLVMRLFKLVDMSG---GILNFLPFLRHFVPRLIGFTELQEIHNALHQYLREIIKEHQXN 712
L K + SG +LN +P L H +P L G ++ A L E++ EH+
Sbjct: 207 DLAQEGLK--EESGFLREVLNAVPVLLH-IPALAG--KVLRFQKAFLTQLDELLTEHRMT 261
Query: 713 LQ-LGAPKDVIDAFLIDM 763
P+D+ +AFL +M
Sbjct: 262 WDPAQPPRDLTEAFLAEM 279
Score = 45.6 bits (103), Expect(2) = 9e-13
Identities = 32/96 (33%), Positives = 51/96 (53%), Gaps = 3/96 (3%)
Frame = +2
Query: 101 RRHRGLC-YPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVV 277
RR R YPPGP PLP +GNLL V +++ + C + +++G++ L+L VV
Sbjct: 25 RRQRWAARYPPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWTPVV 79
Query: 278 VVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKK 379
V+ G+ +RE V++ E RP + FG +
Sbjct: 80 VLNGLAAVREALVTHGEDTADRPPVPITQILGFGPR 115
>BC067432-1|AAH67432.1| 497|Homo sapiens cytochrome P450, family 2,
subfamily D, polypeptide 6 protein.
Length = 497
Score = 48.0 bits (109), Expect(2) = 9e-13
Identities = 37/138 (26%), Positives = 63/138 (45%), Gaps = 4/138 (2%)
Frame = +2
Query: 362 RSFGKKLGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKLC 541
+S + + EE L +G P N + + N++ L G+R++ +D R +L
Sbjct: 147 KSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLL 206
Query: 542 SLVMRLFKLVDMSG---GILNFLPFLRHFVPRLIGFTELQEIHNALHQYLREIIKEHQXN 712
L K + SG +LN +P L H +P L G ++ A L E++ EH+
Sbjct: 207 DLAQEGLK--EESGFLREVLNAVPVLLH-IPALAG--KVLRFQKAFLTQLDELLTEHRMT 261
Query: 713 LQ-LGAPKDVIDAFLIDM 763
P+D+ +AFL +M
Sbjct: 262 WDPAQPPRDLTEAFLAEM 279
Score = 45.6 bits (103), Expect(2) = 9e-13
Identities = 32/96 (33%), Positives = 51/96 (53%), Gaps = 3/96 (3%)
Frame = +2
Query: 101 RRHRGLC-YPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVV 277
RR R YPPGP PLP +GNLL V +++ + C + +++G++ L+L VV
Sbjct: 25 RRQRWAARYPPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWTPVV 79
Query: 278 VVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKK 379
V+ G+ +RE V++ E RP + FG +
Sbjct: 80 VLNGLAAVREALVTHGEDTADRPPVPITQILGFGPR 115
>AY545216-1|AAS55001.1| 497|Homo sapiens cytochrome P4502D6
protein.
Length = 497
Score = 48.0 bits (109), Expect(2) = 9e-13
Identities = 37/138 (26%), Positives = 63/138 (45%), Gaps = 4/138 (2%)
Frame = +2
Query: 362 RSFGKKLGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKLC 541
+S + + EE L +G P N + + N++ L G+R++ +D R +L
Sbjct: 147 KSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLL 206
Query: 542 SLVMRLFKLVDMSG---GILNFLPFLRHFVPRLIGFTELQEIHNALHQYLREIIKEHQXN 712
L K + SG +LN +P L H +P L G ++ A L E++ EH+
Sbjct: 207 DLAQEGLK--EESGFLREVLNAVPVLLH-IPALAG--KVLRFQKAFLTQLDELLTEHRMT 261
Query: 713 LQ-LGAPKDVIDAFLIDM 763
P+D+ +AFL +M
Sbjct: 262 WDPAQPPRDLTEAFLAEM 279
Score = 45.6 bits (103), Expect(2) = 9e-13
Identities = 32/96 (33%), Positives = 51/96 (53%), Gaps = 3/96 (3%)
Frame = +2
Query: 101 RRHRGLC-YPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVV 277
RR R YPPGP PLP +GNLL V +++ + C + +++G++ L+L VV
Sbjct: 25 RRQRWAARYPPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWTPVV 79
Query: 278 VVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKK 379
V+ G+ +RE V++ E RP + FG +
Sbjct: 80 VLNGLAAVREALVTHGEDTADRPPVPITQILGFGPR 115
>DQ282151-1|ABB77899.1| 496|Homo sapiens cytochrome P450 2D6
protein.
Length = 496
Score = 48.0 bits (109), Expect(2) = 9e-13
Identities = 37/138 (26%), Positives = 63/138 (45%), Gaps = 4/138 (2%)
Frame = +2
Query: 362 RSFGKKLGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKLC 541
+S + + EE L +G P N + + N++ L G+R++ +D R +L
Sbjct: 147 KSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLL 206
Query: 542 SLVMRLFKLVDMSG---GILNFLPFLRHFVPRLIGFTELQEIHNALHQYLREIIKEHQXN 712
L K + SG +LN +P L H +P L G ++ A L E++ EH+
Sbjct: 207 DLAQEGLK--EESGFLREVLNAVPVLLH-IPALAG--KVLRFQKAFLTQLDELLTEHRMT 261
Query: 713 LQ-LGAPKDVIDAFLIDM 763
P+D+ +AFL +M
Sbjct: 262 WDPAQPPRDLTEAFLAEM 279
Score = 45.6 bits (103), Expect(2) = 9e-13
Identities = 32/96 (33%), Positives = 51/96 (53%), Gaps = 3/96 (3%)
Frame = +2
Query: 101 RRHRGLC-YPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVV 277
RR R YPPGP PLP +GNLL V +++ + C + +++G++ L+L VV
Sbjct: 25 RRQRWAARYPPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWTPVV 79
Query: 278 VVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKK 379
V+ G+ +RE V++ E RP + FG +
Sbjct: 80 VLNGLAAVREALVTHGEDTADRPPVPITQILGFGPR 115
>DQ282154-1|ABB77902.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 48.0 bits (109), Expect(2) = 1e-12
Identities = 37/138 (26%), Positives = 63/138 (45%), Gaps = 4/138 (2%)
Frame = +2
Query: 362 RSFGKKLGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKLC 541
+S + + EE L +G P N + + N++ L G+R++ +D R +L
Sbjct: 147 KSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLL 206
Query: 542 SLVMRLFKLVDMSG---GILNFLPFLRHFVPRLIGFTELQEIHNALHQYLREIIKEHQXN 712
L K + SG +LN +P L H +P L G ++ A L E++ EH+
Sbjct: 207 DLAQEGLK--EESGFLREVLNAVPVLLH-IPALAG--KVLRFQKAFLTQLDELLTEHRMT 261
Query: 713 LQ-LGAPKDVIDAFLIDM 763
P+D+ +AFL +M
Sbjct: 262 WDPAQPPRDLTEAFLAEM 279
Score = 45.2 bits (102), Expect(2) = 1e-12
Identities = 29/88 (32%), Positives = 48/88 (54%), Gaps = 2/88 (2%)
Frame = +2
Query: 122 YPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELI 301
YPPGP PLP +GNLL V +++ + C + +++G++ L+L VVV+ G+ +
Sbjct: 33 YPPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWTPVVVLNGLAAV 87
Query: 302 RE--VSNREVFEGRPDGFFYTMRSFGKK 379
RE V++ E RP + FG +
Sbjct: 88 REALVTHGEDTADRPPVPITQILGFGPR 115
>EF122242-1|ABO41977.1| 321|Homo sapiens cytochrome P450 2F1
variant protein.
Length = 321
Score = 72.9 bits (171), Expect = 1e-12
Identities = 73/267 (27%), Positives = 120/267 (44%), Gaps = 36/267 (13%)
Frame = +2
Query: 98 SRRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVV 277
S R +G PPGP PLPI+GNLL + + L S++YG++ + LG VV
Sbjct: 23 SSRDKGKL-PPGPRPLPILGNLLLLCSQDMLTSLTKL-----SKEYGSMYTVHLGPRRVV 76
Query: 278 VVTGIELIRE--VSNREVFEGRPD--GFF-YT-----------------------MRSFG 373
V++G + ++E V E F GR D FF +T +R+FG
Sbjct: 77 VLSGYQAVKEALVDQGEEFSGRGDYPAFFNFTKGNGIAFSSGDRWKVLRQFSIQILRNFG 136
Query: 374 -------KKLGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLK 532
+++ EE L+ GEP + ++ NI+ ++ G R+D +D+RL
Sbjct: 137 MGKRSIEERILEEGSFLLAELRKTEGEPFDPTFVLSRSVSNIICSVLFGSRFDYDDERLL 196
Query: 533 KLCSLVMRLFKLVDMS-GGILNFLPFLRHFVPRLIGFTELQEIHNALHQYLREIIKEHQX 709
+ L+ F+++ G + N P L +VP + + L + + +HQ
Sbjct: 197 TIIRLINDNFQIMSSPWGELYNIFPSLLDWVPG--PHQRIFQNFKCLRDLIAHSVHDHQA 254
Query: 710 NLQLGAPKDVIDAFLIDMLESQXDKLT 790
+L +P+D I FL M E + D L+
Sbjct: 255 SLDPRSPRDFIQCFLTKMAEEKEDPLS 281
>CR456430-1|CAG30316.1| 446|Homo sapiens CYP2D6 protein.
Length = 446
Score = 72.1 bits (169), Expect = 2e-12
Identities = 65/228 (28%), Positives = 106/228 (46%), Gaps = 7/228 (3%)
Frame = +2
Query: 101 RRHRGLC-YPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVV 277
RR R YPPGP PLP +GNLL V +++ + C + +++G++ L+L VV
Sbjct: 25 RRQRWAARYPPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWTPVV 79
Query: 278 VVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGEECEALVQLRLADAGEPILVNQ 451
V+ G+ +RE V++ E RP + FG + G P N
Sbjct: 80 VLNGLAAVREALVTHGEDTADRPPVPITQILGFGPR--------------SQGRPFRPNG 125
Query: 452 MFHITIVNILWRLVAGKRYDLEDQRLKKLCSLVMRLFKLVDMSG---GILNFLPFLRHFV 622
+ + N++ L G+R++ +D R +L L K + SG +LN +P L H +
Sbjct: 126 LLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLK--EESGFLREVLNAVPVLLH-I 182
Query: 623 PRLIGFTELQEIHNALHQYLREIIKEHQXNLQ-LGAPKDVIDAFLIDM 763
P L G ++ A L E++ EH+ P+D+ +AFL +M
Sbjct: 183 PALAG--KVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEM 228
>BC106757-1|AAI06758.1| 446|Homo sapiens cytochrome P450, family 2,
subfamily D, polypeptide 6 protein.
Length = 446
Score = 72.1 bits (169), Expect = 2e-12
Identities = 65/228 (28%), Positives = 106/228 (46%), Gaps = 7/228 (3%)
Frame = +2
Query: 101 RRHRGLC-YPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVV 277
RR R YPPGP PLP +GNLL V +++ + C + +++G++ L+L VV
Sbjct: 25 RRQRWAARYPPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWTPVV 79
Query: 278 VVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGEECEALVQLRLADAGEPILVNQ 451
V+ G+ +RE V++ E RP + FG + G P N
Sbjct: 80 VLNGLAAVREALVTHGEDTADRPPVPITQILGFGPR--------------SQGRPFRPNG 125
Query: 452 MFHITIVNILWRLVAGKRYDLEDQRLKKLCSLVMRLFKLVDMSG---GILNFLPFLRHFV 622
+ + N++ L G+R++ +D R +L L K + SG +LN +P L H +
Sbjct: 126 LLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLK--EESGFLREVLNAVPVLLH-I 182
Query: 623 PRLIGFTELQEIHNALHQYLREIIKEHQXNLQ-LGAPKDVIDAFLIDM 763
P L G ++ A L E++ EH+ P+D+ +AFL +M
Sbjct: 183 PALAG--KVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEM 228
>BC066877-1|AAH66877.1| 446|Homo sapiens CYP2D6 protein protein.
Length = 446
Score = 72.1 bits (169), Expect = 2e-12
Identities = 65/228 (28%), Positives = 106/228 (46%), Gaps = 7/228 (3%)
Frame = +2
Query: 101 RRHRGLC-YPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVV 277
RR R YPPGP PLP +GNLL V +++ + C + +++G++ L+L VV
Sbjct: 25 RRQRWAARYPPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWTPVV 79
Query: 278 VVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKKLGEECEALVQLRLADAGEPILVNQ 451
V+ G+ +RE V++ E RP + FG + G P N
Sbjct: 80 VLNGLAAVREALVTHGEDTADRPPVPITQILGFGPR--------------SQGRPFRPNG 125
Query: 452 MFHITIVNILWRLVAGKRYDLEDQRLKKLCSLVMRLFKLVDMSG---GILNFLPFLRHFV 622
+ + N++ L G+R++ +D R +L L K + SG +LN +P L H +
Sbjct: 126 LLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLK--EESGFLREVLNAVPVLLH-I 182
Query: 623 PRLIGFTELQEIHNALHQYLREIIKEHQXNLQ-LGAPKDVIDAFLIDM 763
P L G ++ A L E++ EH+ P+D+ +AFL +M
Sbjct: 183 PALAG--KVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEM 228
>J02906-1|AAA52156.1| 491|Homo sapiens CYP2F1 protein.
Length = 491
Score = 46.0 bits (104), Expect(2) = 6e-12
Identities = 31/84 (36%), Positives = 45/84 (53%), Gaps = 2/84 (2%)
Frame = +2
Query: 98 SRRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVV 277
S R +G PPGP PL I+GNLL + + L S++YG++ + LG VV
Sbjct: 23 SSRDKGKL-PPGPRPLSILGNLLLLCSQDMLTSLTKL-----SKEYGSMYTVHLGPRRVV 76
Query: 278 VVTGIELIRE--VSNREVFEGRPD 343
V++G + ++E V E F GR D
Sbjct: 77 VLSGYQAVKEALVDQGEEFSGRGD 100
Score = 44.8 bits (101), Expect(2) = 6e-12
Identities = 38/146 (26%), Positives = 67/146 (45%), Gaps = 3/146 (2%)
Frame = +2
Query: 362 RSFGKKLGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKLC 541
RS +++ EE L+ GEP + ++ NI+ ++ G R+D +D+RL +
Sbjct: 140 RSIEERILEEGSFLLADVRKTEGEPFDPTFVLSRSVSNIICSVLFGSRFDYDDERLLTII 199
Query: 542 SLVMRLFKLVDMSGGILNFLPFLRHFVPRLIGFTELQEIHNALHQ---YLREIIKEHQXN 712
L+ F+++ G L L P L+ + + H + Q LR++I +
Sbjct: 200 RLINDNFQIMSSPWGEL--YDILDPRFPSLLDW--VPGPHQRIFQNFKCLRDLIAHSVHD 255
Query: 713 LQLGAPKDVIDAFLIDMLESQXDKLT 790
Q +P+D I FL M E + D L+
Sbjct: 256 HQASSPRDFIQCFLTKMAEEKEDPLS 281
>DQ282152-1|ABB77900.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 48.0 bits (109), Expect(2) = 8e-12
Identities = 37/138 (26%), Positives = 63/138 (45%), Gaps = 4/138 (2%)
Frame = +2
Query: 362 RSFGKKLGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKLC 541
+S + + EE L +G P N + + N++ L G+R++ +D R +L
Sbjct: 147 KSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLL 206
Query: 542 SLVMRLFKLVDMSG---GILNFLPFLRHFVPRLIGFTELQEIHNALHQYLREIIKEHQXN 712
L K + SG +LN +P L H +P L G ++ A L E++ EH+
Sbjct: 207 DLAQEGLK--EESGFLREVLNAVPVLLH-IPALAG--KVLRFQKAFLTQLDELLTEHRMT 261
Query: 713 LQ-LGAPKDVIDAFLIDM 763
P+D+ +AFL +M
Sbjct: 262 WDPAQPPRDLTEAFLAEM 279
Score = 42.3 bits (95), Expect(2) = 8e-12
Identities = 31/96 (32%), Positives = 50/96 (52%), Gaps = 3/96 (3%)
Frame = +2
Query: 101 RRHRGLC-YPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVV 277
RR R Y PGP PLP +GNLL V +++ + C + +++G++ L+L VV
Sbjct: 25 RRQRWAARYSPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWTPVV 79
Query: 278 VVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKK 379
V+ G+ +RE V++ E RP + FG +
Sbjct: 80 VLNGLAAVREALVTHGEDTADRPPVPITQILGFGPR 115
>DQ211354-2|ABB01372.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 48.0 bits (109), Expect(2) = 8e-12
Identities = 37/138 (26%), Positives = 63/138 (45%), Gaps = 4/138 (2%)
Frame = +2
Query: 362 RSFGKKLGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKLC 541
+S + + EE L +G P N + + N++ L G+R++ +D R +L
Sbjct: 147 KSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLL 206
Query: 542 SLVMRLFKLVDMSG---GILNFLPFLRHFVPRLIGFTELQEIHNALHQYLREIIKEHQXN 712
L K + SG +LN +P L H +P L G ++ A L E++ EH+
Sbjct: 207 DLAQEGLK--EESGFLREVLNAVPVLLH-IPALAG--KVLRFQKAFLTQLDELLTEHRMT 261
Query: 713 LQ-LGAPKDVIDAFLIDM 763
P+D+ +AFL +M
Sbjct: 262 WDPAQPPRDLTEAFLAEM 279
Score = 42.3 bits (95), Expect(2) = 8e-12
Identities = 31/96 (32%), Positives = 50/96 (52%), Gaps = 3/96 (3%)
Frame = +2
Query: 101 RRHRGLC-YPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVV 277
RR R Y PGP PLP +GNLL V +++ + C + +++G++ L+L VV
Sbjct: 25 RRQRWAARYSPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWTPVV 79
Query: 278 VVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKK 379
V+ G+ +RE V++ E RP + FG +
Sbjct: 80 VLNGLAAVREALVTHGEDTADRPPVPITQILGFGPR 115
>DQ211353-2|ABB01371.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 48.0 bits (109), Expect(2) = 8e-12
Identities = 37/138 (26%), Positives = 63/138 (45%), Gaps = 4/138 (2%)
Frame = +2
Query: 362 RSFGKKLGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKLC 541
+S + + EE L +G P N + + N++ L G+R++ +D R +L
Sbjct: 147 KSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLL 206
Query: 542 SLVMRLFKLVDMSG---GILNFLPFLRHFVPRLIGFTELQEIHNALHQYLREIIKEHQXN 712
L K + SG +LN +P L H +P L G ++ A L E++ EH+
Sbjct: 207 DLAQEGLK--EESGFLREVLNAVPVLLH-IPALAG--KVLRFQKAFLTQLDELLTEHRMT 261
Query: 713 LQ-LGAPKDVIDAFLIDM 763
P+D+ +AFL +M
Sbjct: 262 WDPAQPPRDLTEAFLAEM 279
Score = 42.3 bits (95), Expect(2) = 8e-12
Identities = 31/96 (32%), Positives = 50/96 (52%), Gaps = 3/96 (3%)
Frame = +2
Query: 101 RRHRGLC-YPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVV 277
RR R Y PGP PLP +GNLL V +++ + C + +++G++ L+L VV
Sbjct: 25 RRQRWAARYSPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWTPVV 79
Query: 278 VVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKK 379
V+ G+ +RE V++ E RP + FG +
Sbjct: 80 VLNGLAAVREALVTHGEDTADRPPVPITQILGFGPR 115
>DQ211353-1|ABB01370.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 48.0 bits (109), Expect(2) = 8e-12
Identities = 37/138 (26%), Positives = 63/138 (45%), Gaps = 4/138 (2%)
Frame = +2
Query: 362 RSFGKKLGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKLC 541
+S + + EE L +G P N + + N++ L G+R++ +D R +L
Sbjct: 147 KSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLL 206
Query: 542 SLVMRLFKLVDMSG---GILNFLPFLRHFVPRLIGFTELQEIHNALHQYLREIIKEHQXN 712
L K + SG +LN +P L H +P L G ++ A L E++ EH+
Sbjct: 207 DLAQEGLK--EESGFLREVLNAVPVLLH-IPALAG--KVLRFQKAFLTQLDELLTEHRMT 261
Query: 713 LQ-LGAPKDVIDAFLIDM 763
P+D+ +AFL +M
Sbjct: 262 WDPAQPPRDLTEAFLAEM 279
Score = 42.3 bits (95), Expect(2) = 8e-12
Identities = 31/96 (32%), Positives = 50/96 (52%), Gaps = 3/96 (3%)
Frame = +2
Query: 101 RRHRGLC-YPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVV 277
RR R Y PGP PLP +GNLL V +++ + C + +++G++ L+L VV
Sbjct: 25 RRQRWAARYSPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWTPVV 79
Query: 278 VVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKK 379
V+ G+ +RE V++ E RP + FG +
Sbjct: 80 VLNGLAAVREALVTHGEDTADRPPVPITQILGFGPR 115
>M61856-1|AAB59356.1| 490|Homo sapiens cytochrome protein.
Length = 490
Score = 48.0 bits (109), Expect(2) = 8e-12
Identities = 40/152 (26%), Positives = 70/152 (46%), Gaps = 5/152 (3%)
Frame = +2
Query: 362 RSFGKKLGEECEALVQ-LRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKL 538
RS ++ EE LV+ LR +A P + N++ ++ R+D +DQR L
Sbjct: 139 RSIEDRVQEEARCLVEELRKTNAS-PCDPTFILGCAPCNVICSVIFHDRFDYKDQRFLNL 197
Query: 539 CSLVMRLFKLVDMSG-GILNFLPFLRHFVPRLIGFTELQEIHNALHQYLREIIKEHQXNL 715
+++ + N P L ++P ++ E + Y+ E IKEHQ +L
Sbjct: 198 MEKFNENLRILSSPWIQVCNNFPALIDYLPG--SHNKIAENFAYIKSYVLERIKEHQESL 255
Query: 716 QLGAPKDVIDAFLIDMLE---SQXDKLTLDDL 802
+ + +D ID FLI M + +Q + T++ L
Sbjct: 256 DMNSARDFIDCFLIKMEQEKHNQQSEFTVESL 287
Score = 42.3 bits (95), Expect(2) = 8e-12
Identities = 30/89 (33%), Positives = 44/89 (49%), Gaps = 2/89 (2%)
Frame = +2
Query: 125 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIR 304
P GPTPLPI+GN+L + K ++S+ YG + + G +VV+ G E ++
Sbjct: 30 PSGPTPLPIIGNILQL-----DVKDMSKSLTNFSKVYGPVFTVYFGLKPIVVLHGYEAVK 84
Query: 305 E--VSNREVFEGRPDGFFYTMRSFGKKLG 385
E + + E F GR G F K LG
Sbjct: 85 EALIDHGEEFSGR--GSFPVAEKVNKGLG 111
>L16876-1|AAA02630.1| 490|Homo sapiens cytochrome P-4502C18
protein.
Length = 490
Score = 48.0 bits (109), Expect(2) = 8e-12
Identities = 40/152 (26%), Positives = 70/152 (46%), Gaps = 5/152 (3%)
Frame = +2
Query: 362 RSFGKKLGEECEALVQ-LRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKL 538
RS ++ EE LV+ LR +A P + N++ ++ R+D +DQR L
Sbjct: 139 RSIEDRVQEEARCLVEELRKTNAS-PCDPTFILGCAPCNVICSVIFHDRFDYKDQRFLNL 197
Query: 539 CSLVMRLFKLVDMSG-GILNFLPFLRHFVPRLIGFTELQEIHNALHQYLREIIKEHQXNL 715
+++ + N P L ++P ++ E + Y+ E IKEHQ +L
Sbjct: 198 MEKFNENLRILSSPWIQVCNNFPALIDYLPG--SHNKIAENFAYIKSYVLERIKEHQESL 255
Query: 716 QLGAPKDVIDAFLIDMLE---SQXDKLTLDDL 802
+ + +D ID FLI M + +Q + T++ L
Sbjct: 256 DMNSARDFIDCFLIKMEQEKHNQQSEFTVESL 287
Score = 42.3 bits (95), Expect(2) = 8e-12
Identities = 30/89 (33%), Positives = 44/89 (49%), Gaps = 2/89 (2%)
Frame = +2
Query: 125 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIR 304
P GPTPLPI+GN+L + K ++S+ YG + + G +VV+ G E ++
Sbjct: 30 PSGPTPLPIIGNILQL-----DVKDMSKSLTNFSKVYGPVFTVYFGLKPIVVLHGYEAVK 84
Query: 305 E--VSNREVFEGRPDGFFYTMRSFGKKLG 385
E + + E F GR G F K LG
Sbjct: 85 EALIDHGEEFSGR--GSFPVAEKVNKGLG 111
>BC096258-1|AAH96258.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 protein.
Length = 490
Score = 48.0 bits (109), Expect(2) = 8e-12
Identities = 40/152 (26%), Positives = 70/152 (46%), Gaps = 5/152 (3%)
Frame = +2
Query: 362 RSFGKKLGEECEALVQ-LRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKL 538
RS ++ EE LV+ LR +A P + N++ ++ R+D +DQR L
Sbjct: 139 RSIEDRVQEEARCLVEELRKTNAS-PCDPTFILGCAPCNVICSVIFHDRFDYKDQRFLNL 197
Query: 539 CSLVMRLFKLVDMSG-GILNFLPFLRHFVPRLIGFTELQEIHNALHQYLREIIKEHQXNL 715
+++ + N P L ++P ++ E + Y+ E IKEHQ +L
Sbjct: 198 MEKFNENLRILSSPWIQVCNNFPALIDYLPG--SHNKIAENFAYIKSYVLERIKEHQESL 255
Query: 716 QLGAPKDVIDAFLIDMLE---SQXDKLTLDDL 802
+ + +D ID FLI M + +Q + T++ L
Sbjct: 256 DMNSARDFIDCFLIKMEQEKHNQQSEFTVESL 287
Score = 42.3 bits (95), Expect(2) = 8e-12
Identities = 30/89 (33%), Positives = 44/89 (49%), Gaps = 2/89 (2%)
Frame = +2
Query: 125 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIR 304
P GPTPLPI+GN+L + K ++S+ YG + + G +VV+ G E ++
Sbjct: 30 PSGPTPLPIIGNILQL-----DVKDMSKSLTNFSKVYGPVFTVYFGLKPIVVLHGYEAVK 84
Query: 305 E--VSNREVFEGRPDGFFYTMRSFGKKLG 385
E + + E F GR G F K LG
Sbjct: 85 EALIDHGEEFSGR--GSFPVAEKVNKGLG 111
>BC096257-1|AAH96257.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 protein.
Length = 490
Score = 48.0 bits (109), Expect(2) = 8e-12
Identities = 40/152 (26%), Positives = 70/152 (46%), Gaps = 5/152 (3%)
Frame = +2
Query: 362 RSFGKKLGEECEALVQ-LRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKL 538
RS ++ EE LV+ LR +A P + N++ ++ R+D +DQR L
Sbjct: 139 RSIEDRVQEEARCLVEELRKTNAS-PCDPTFILGCAPCNVICSVIFHDRFDYKDQRFLNL 197
Query: 539 CSLVMRLFKLVDMSG-GILNFLPFLRHFVPRLIGFTELQEIHNALHQYLREIIKEHQXNL 715
+++ + N P L ++P ++ E + Y+ E IKEHQ +L
Sbjct: 198 MEKFNENLRILSSPWIQVCNNFPALIDYLPG--SHNKIAENFAYIKSYVLERIKEHQESL 255
Query: 716 QLGAPKDVIDAFLIDMLE---SQXDKLTLDDL 802
+ + +D ID FLI M + +Q + T++ L
Sbjct: 256 DMNSARDFIDCFLIKMEQEKHNQQSEFTVESL 287
Score = 42.3 bits (95), Expect(2) = 8e-12
Identities = 30/89 (33%), Positives = 44/89 (49%), Gaps = 2/89 (2%)
Frame = +2
Query: 125 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIR 304
P GPTPLPI+GN+L + K ++S+ YG + + G +VV+ G E ++
Sbjct: 30 PSGPTPLPIIGNILQL-----DVKDMSKSLTNFSKVYGPVFTVYFGLKPIVVLHGYEAVK 84
Query: 305 E--VSNREVFEGRPDGFFYTMRSFGKKLG 385
E + + E F GR G F K LG
Sbjct: 85 EALIDHGEEFSGR--GSFPVAEKVNKGLG 111
>BC069666-1|AAH69666.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 protein.
Length = 490
Score = 48.0 bits (109), Expect(2) = 8e-12
Identities = 40/152 (26%), Positives = 70/152 (46%), Gaps = 5/152 (3%)
Frame = +2
Query: 362 RSFGKKLGEECEALVQ-LRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKL 538
RS ++ EE LV+ LR +A P + N++ ++ R+D +DQR L
Sbjct: 139 RSIEDRVQEEARCLVEELRKTNAS-PCDPTFILGCAPCNVICSVIFHDRFDYKDQRFLNL 197
Query: 539 CSLVMRLFKLVDMSG-GILNFLPFLRHFVPRLIGFTELQEIHNALHQYLREIIKEHQXNL 715
+++ + N P L ++P ++ E + Y+ E IKEHQ +L
Sbjct: 198 MEKFNENLRILSSPWIQVCNNFPALIDYLPG--SHNKIAENFAYIKSYVLERIKEHQESL 255
Query: 716 QLGAPKDVIDAFLIDMLE---SQXDKLTLDDL 802
+ + +D ID FLI M + +Q + T++ L
Sbjct: 256 DMNSARDFIDCFLIKMEQEKHNQQSEFTVESL 287
Score = 42.3 bits (95), Expect(2) = 8e-12
Identities = 30/89 (33%), Positives = 44/89 (49%), Gaps = 2/89 (2%)
Frame = +2
Query: 125 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIR 304
P GPTPLPI+GN+L + K ++S+ YG + + G +VV+ G E ++
Sbjct: 30 PSGPTPLPIIGNILQL-----DVKDMSKSLTNFSKVYGPVFTVYFGLKPIVVLHGYEAVK 84
Query: 305 E--VSNREVFEGRPDGFFYTMRSFGKKLG 385
E + + E F GR G F K LG
Sbjct: 85 EALIDHGEEFSGR--GSFPVAEKVNKGLG 111
>AL583836-1|CAH74067.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 protein.
Length = 490
Score = 48.0 bits (109), Expect(2) = 8e-12
Identities = 40/152 (26%), Positives = 70/152 (46%), Gaps = 5/152 (3%)
Frame = +2
Query: 362 RSFGKKLGEECEALVQ-LRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKL 538
RS ++ EE LV+ LR +A P + N++ ++ R+D +DQR L
Sbjct: 139 RSIEDRVQEEARCLVEELRKTNAS-PCDPTFILGCAPCNVICSVIFHDRFDYKDQRFLNL 197
Query: 539 CSLVMRLFKLVDMSG-GILNFLPFLRHFVPRLIGFTELQEIHNALHQYLREIIKEHQXNL 715
+++ + N P L ++P ++ E + Y+ E IKEHQ +L
Sbjct: 198 MEKFNENLRILSSPWIQVCNNFPALIDYLPG--SHNKIAENFAYIKSYVLERIKEHQESL 255
Query: 716 QLGAPKDVIDAFLIDMLE---SQXDKLTLDDL 802
+ + +D ID FLI M + +Q + T++ L
Sbjct: 256 DMNSARDFIDCFLIKMEQEKHNQQSEFTVESL 287
Score = 42.3 bits (95), Expect(2) = 8e-12
Identities = 30/89 (33%), Positives = 44/89 (49%), Gaps = 2/89 (2%)
Frame = +2
Query: 125 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIR 304
P GPTPLPI+GN+L + K ++S+ YG + + G +VV+ G E ++
Sbjct: 30 PSGPTPLPIIGNILQL-----DVKDMSKSLTNFSKVYGPVFTVYFGLKPIVVLHGYEAVK 84
Query: 305 E--VSNREVFEGRPDGFFYTMRSFGKKLG 385
E + + E F GR G F K LG
Sbjct: 85 EALIDHGEEFSGR--GSFPVAEKVNKGLG 111
>BC096259-1|AAH96259.1| 443|Homo sapiens CYP2C18 protein protein.
Length = 443
Score = 48.0 bits (109), Expect(2) = 8e-12
Identities = 40/152 (26%), Positives = 70/152 (46%), Gaps = 5/152 (3%)
Frame = +2
Query: 362 RSFGKKLGEECEALVQ-LRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKL 538
RS ++ EE LV+ LR +A P + N++ ++ R+D +DQR L
Sbjct: 139 RSIEDRVQEEARCLVEELRKTNAS-PCDPTFILGCAPCNVICSVIFHDRFDYKDQRFLNL 197
Query: 539 CSLVMRLFKLVDMSG-GILNFLPFLRHFVPRLIGFTELQEIHNALHQYLREIIKEHQXNL 715
+++ + N P L ++P ++ E + Y+ E IKEHQ +L
Sbjct: 198 MEKFNENLRILSSPWIQVCNNFPALIDYLPG--SHNKIAENFAYIKSYVLERIKEHQESL 255
Query: 716 QLGAPKDVIDAFLIDMLE---SQXDKLTLDDL 802
+ + +D ID FLI M + +Q + T++ L
Sbjct: 256 DMNSARDFIDCFLIKMEQEKHNQQSEFTVESL 287
Score = 42.3 bits (95), Expect(2) = 8e-12
Identities = 30/89 (33%), Positives = 44/89 (49%), Gaps = 2/89 (2%)
Frame = +2
Query: 125 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIR 304
P GPTPLPI+GN+L + K ++S+ YG + + G +VV+ G E ++
Sbjct: 30 PSGPTPLPIIGNILQL-----DVKDMSKSLTNFSKVYGPVFTVYFGLKPIVVLHGYEAVK 84
Query: 305 E--VSNREVFEGRPDGFFYTMRSFGKKLG 385
E + + E F GR G F K LG
Sbjct: 85 EALIDHGEEFSGR--GSFPVAEKVNKGLG 111
>M33317-1|AAA52138.1| 494|Homo sapiens CYP2A protein.
Length = 494
Score = 70.1 bits (164), Expect = 9e-12
Identities = 74/268 (27%), Positives = 121/268 (45%), Gaps = 38/268 (14%)
Frame = +2
Query: 101 RRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 280
R+ RG PPGPTPLP +GN L + + + C ++ +S+ YG + + LG VVV
Sbjct: 27 RKSRGKL-PPGPTPLPFIGNYLQL---NTEHICDSIM--KFSECYGPVFTIHLGPRRVVV 80
Query: 281 VTGIELIR--------EVSNRE-------VFEGRPDGF-------------FYTMRSFG- 373
+ G + +R E S R VF+G F T+R FG
Sbjct: 81 LCGHDAVREALVDQAEEFSGRGEQATFDWVFKGYGVAFSNGERAKQLLRFAIATLRDFGV 140
Query: 374 ------KKLGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKK 535
+++ EE L++ + G I T+ N++ +V G R+D ED+
Sbjct: 141 GKRGIEERIQEESGFLIEAIRSSHGANIDPTFFLSRTVSNVISSIVFGDRFDYEDKEFLS 200
Query: 536 LCSLVMRLFKLVDMSGGIL--NFLPFLRHFV-PRLIGFTELQEIHNALHQYLREIIKEHQ 706
L S+++ +F+ S G L F ++H P+ F LQ L ++ + ++ +Q
Sbjct: 201 LLSMMLGIFQFTSTSTGQLYEMFSSVMKHLPGPQQQAFKLLQ----GLEDFIAKKVEHNQ 256
Query: 707 XNLQLGAPKDVIDAFLIDMLESQXDKLT 790
L +P+D ID+FLI M E + + T
Sbjct: 257 RTLDPNSPQDFIDSFLIHMQEEEKNPNT 284
>EF122241-1|ABO41976.1| 491|Homo sapiens cytochrome P450 2F1
variant protein.
Length = 491
Score = 69.3 bits (162), Expect = 2e-11
Identities = 72/267 (26%), Positives = 119/267 (44%), Gaps = 36/267 (13%)
Frame = +2
Query: 98 SRRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVV 277
S R +G PPGP PL I+GNLL + + L S++YG++ + LG VV
Sbjct: 23 SSRDKGKL-PPGPRPLSILGNLLLLCSQDMLTSLTKL-----SKEYGSMYTVHLGPRRVV 76
Query: 278 VVTGIELIRE--VSNREVFEGRPD--GFF-YT-----------------------MRSFG 373
V++G + ++E V E F GR D FF +T +R+FG
Sbjct: 77 VLSGYQAVKEALVDQGEEFSGRGDYPAFFNFTKGNGIAFSSGDRWKVLRQFSIQILRNFG 136
Query: 374 -------KKLGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLK 532
+++ EE L+ GEP + ++ NI+ ++ G R+D +D+RL
Sbjct: 137 MGKRSIEERILEEGSFLLAELRKTEGEPFDPTFVLSRSVSNIICSVLFGSRFDYDDERLL 196
Query: 533 KLCSLVMRLFKLVDMS-GGILNFLPFLRHFVPRLIGFTELQEIHNALHQYLREIIKEHQX 709
+ L+ F+++ G + N P L +VP + + L + + +HQ
Sbjct: 197 TIIRLINDNFQIMSSPWGELYNIFPSLLDWVPG--PHQRIFQNFKCLRDLIAHSVHDHQA 254
Query: 710 NLQLGAPKDVIDAFLIDMLESQXDKLT 790
+L +P+D I FL M E + D L+
Sbjct: 255 SLDPRSPRDFIHCFLTKMAEEKEDPLS 281
>AK223510-1|BAD97230.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 variant protein.
Length = 490
Score = 48.0 bits (109), Expect(2) = 2e-11
Identities = 40/152 (26%), Positives = 70/152 (46%), Gaps = 5/152 (3%)
Frame = +2
Query: 362 RSFGKKLGEECEALVQ-LRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKL 538
RS ++ EE LV+ LR +A P + N++ ++ R+D +DQR L
Sbjct: 139 RSIEDRVQEEARCLVEELRKTNAS-PCDPTFILGCAPCNVICSVIFHDRFDYKDQRFLNL 197
Query: 539 CSLVMRLFKLVDMSG-GILNFLPFLRHFVPRLIGFTELQEIHNALHQYLREIIKEHQXNL 715
+++ + N P L ++P ++ E + Y+ E IKEHQ +L
Sbjct: 198 MEKFNENLRILSSPWIQVCNNFPALIDYLPG--SHNKIAENFAYIKSYVLERIKEHQESL 255
Query: 716 QLGAPKDVIDAFLIDMLE---SQXDKLTLDDL 802
+ + +D ID FLI M + +Q + T++ L
Sbjct: 256 DMNSARDFIDCFLIKMEQEKHNQQSEFTVESL 287
Score = 41.1 bits (92), Expect(2) = 2e-11
Identities = 30/89 (33%), Positives = 44/89 (49%), Gaps = 2/89 (2%)
Frame = +2
Query: 125 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIR 304
P GPTPLPI+GN+L + K ++S+ YG + + G +VV+ G E ++
Sbjct: 30 PSGPTPLPIIGNILQL-----DVKDMSKSLTNFSKVYGPVFTVYFGLKPIVVLHGYEAVK 84
Query: 305 E--VSNREVFEGRPDGFFYTMRSFGKKLG 385
E + + E F GR G F K LG
Sbjct: 85 EALIDHGEEFFGR--GSFPVAEKVNKGLG 111
>BC117165-1|AAI17166.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 7 protein.
Length = 494
Score = 67.7 bits (158), Expect = 5e-11
Identities = 73/268 (27%), Positives = 120/268 (44%), Gaps = 38/268 (14%)
Frame = +2
Query: 101 RRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 280
R+ RG PPGPTPLP +GN L + + + C ++ +S+ YG + + LG VV
Sbjct: 27 RKSRGKL-PPGPTPLPFIGNYLQL---NTEHICDSIM--KFSECYGPVFTIHLGPRRAVV 80
Query: 281 VTGIELIR--------EVSNRE-------VFEGRPDGF-------------FYTMRSFG- 373
+ G + +R E S R VF+G F T+R FG
Sbjct: 81 LCGHDAVREALVDQAEEFSGRGEQATFDWVFKGYGVAFSNGERAKQLLRFAIATLRDFGV 140
Query: 374 ------KKLGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKK 535
+++ EE L++ + G I T+ N++ +V G R+D ED+
Sbjct: 141 GKRGIEERIQEESGFLIEAIRSTHGANIDPTFFLSRTVSNVISSIVFGDRFDYEDKEFLS 200
Query: 536 LCSLVMRLFKLVDMSGGIL--NFLPFLRHFV-PRLIGFTELQEIHNALHQYLREIIKEHQ 706
L S+++ +F+ S G L F ++H P+ F LQ L ++ + ++ +Q
Sbjct: 201 LLSVMLGIFQFTSTSTGQLYEMFSSVMKHLPGPQQQAFKLLQ----GLEDFIAKKVEHNQ 256
Query: 707 XNLQLGAPKDVIDAFLIDMLESQXDKLT 790
L +P+D ID+FLI M E + + T
Sbjct: 257 RTLDPNSPRDFIDSFLIRMQEEEKNPNT 284
>BC109056-1|AAI09057.1| 320|Homo sapiens CYP2F1 protein protein.
Length = 320
Score = 67.7 bits (158), Expect = 5e-11
Identities = 71/267 (26%), Positives = 119/267 (44%), Gaps = 36/267 (13%)
Frame = +2
Query: 98 SRRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVV 277
S R +G PPGP PL I+GNLL + + L S++YG++ + LG VV
Sbjct: 23 SSRDKGKL-PPGPRPLSILGNLLLLCSQDMLTSLTKL-----SKEYGSMYTVHLGPRRVV 76
Query: 278 VVTGIELIRE--VSNREVFEGRPD--GFF-YT-----------------------MRSFG 373
V++G + ++E V E F GR D FF +T +R+FG
Sbjct: 77 VLSGYQAVKEALVDQGEEFSGRGDYPAFFNFTKGNGIAFSSGDRWKVLRQFSIQILRNFG 136
Query: 374 -------KKLGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLK 532
+++ EE L+ GEP + ++ NI+ ++ G R+D +D+RL
Sbjct: 137 MGKRSIEERILEEGSFLLAELRKTEGEPFDPTFVLSRSVSNIICSVLFGSRFDYDDERLL 196
Query: 533 KLCSLVMRLFKLVDMS-GGILNFLPFLRHFVPRLIGFTELQEIHNALHQYLREIIKEHQX 709
+ L+ F+++ G + + P L +VP + + L + + +HQ
Sbjct: 197 TIIRLINDNFQIMSSPWGELYDIFPSLLDWVPG--PHQRIFQNFKCLRDLIAHSVHDHQA 254
Query: 710 NLQLGAPKDVIDAFLIDMLESQXDKLT 790
+L +P+D I FL M E + D L+
Sbjct: 255 SLDPRSPRDFIQCFLTKMAEEKEDPLS 281
>U22029-1|AAB40520.1| 494|Homo sapiens cytochrome P450 protein.
Length = 494
Score = 67.3 bits (157), Expect = 6e-11
Identities = 73/268 (27%), Positives = 120/268 (44%), Gaps = 38/268 (14%)
Frame = +2
Query: 101 RRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 280
R+ RG PPGPTPLP +GN L + + + C ++ +S+ YG + + LG VVV
Sbjct: 27 RKSRGKL-PPGPTPLPFIGNYLQL---NTEHICDSIM--KFSECYGPVFTIHLGPRRVVV 80
Query: 281 VTGIELIR--------EVSNRE-------VFEGRPDGF-------------FYTMRSFG- 373
+ G + +R E S R VF+G F T+R FG
Sbjct: 81 LCGHDAVREALVDQAEEFSGRGEQATFEWVFKGYGVAFSNGERAKQLLRFAIATLRDFGV 140
Query: 374 ------KKLGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKK 535
+++ EE L++ + G I T+ N++ +V G R+D ED+
Sbjct: 141 GKRGIEERIQEESGFLIEAIRSTHGANIDPTFFLSRTVSNVISSIVFGDRFDYEDKEFLS 200
Query: 536 LCSLVMRLFKLVDMSGGIL--NFLPFLRHFV-PRLIGFTELQEIHNALHQYLREIIKEHQ 706
L S+++ +F+ S G L F ++H P+ F L L ++ + ++ +Q
Sbjct: 201 LLSMMLGIFQFTSTSTGQLYEMFSSLMKHLPGPQQQAFKLLL----GLEDFIAKKVEHNQ 256
Query: 707 XNLQLGAPKDVIDAFLIDMLESQXDKLT 790
L +P+D ID+FLI M E + + T
Sbjct: 257 RTLDPNSPQDFIDSFLIHMQEEEKNPNT 284
>AK223113-1|BAD96833.1| 512|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 1 variant protein.
Length = 512
Score = 63.7 bits (148), Expect = 7e-10
Identities = 35/93 (37%), Positives = 59/93 (63%), Gaps = 2/93 (2%)
Frame = +2
Query: 110 RGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTG 289
+GL PPGP P++G++L++ K HL SQ+YG++L +R+GS VVV++G
Sbjct: 35 KGLKNPPGPWDWPLIGHMLTL------GKNPHLALSRMSQQYGDVLQIRIGSTPVVVLSG 88
Query: 290 IELIRE--VSNREVFEGRPDGFFYTMRSFGKKL 382
++ IR+ V + F+GRPD + +T+ S G+ +
Sbjct: 89 LDTIRQALVRQGDDFKGRPDLYTFTLISNGQSM 121
>AK223108-1|BAD96828.1| 512|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 1 variant protein.
Length = 512
Score = 63.7 bits (148), Expect = 7e-10
Identities = 35/93 (37%), Positives = 59/93 (63%), Gaps = 2/93 (2%)
Frame = +2
Query: 110 RGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTG 289
+GL PPGP P++G++L++ K HL SQ+YG++L +R+GS VVV++G
Sbjct: 35 KGLKNPPGPWDWPLIGHMLTL------GKNPHLALSRMSQQYGDVLQIRIGSTPVVVLSG 88
Query: 290 IELIRE--VSNREVFEGRPDGFFYTMRSFGKKL 382
++ IR+ V + F+GRPD + +T+ S G+ +
Sbjct: 89 LDTIRQALVRQGDDFKGRPDLYTFTLISNGQSM 121
>X04300-1|CAA27843.1| 512|Homo sapiens P-450 c protein.
Length = 512
Score = 63.3 bits (147), Expect = 1e-09
Identities = 35/93 (37%), Positives = 59/93 (63%), Gaps = 2/93 (2%)
Frame = +2
Query: 110 RGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTG 289
+GL PPGP P++G++L++ K HL SQ+YG++L +R+GS VVV++G
Sbjct: 35 KGLKNPPGPWGWPLIGHMLTL------GKNPHLALSRMSQQYGDVLQIRIGSTPVVVLSG 88
Query: 290 IELIRE--VSNREVFEGRPDGFFYTMRSFGKKL 382
++ IR+ V + F+GRPD + +T+ S G+ +
Sbjct: 89 LDTIRQALVRQGDDFKGRPDLYTFTLISNGQSM 121
>X02612-1|CAA26458.1| 512|Homo sapiens cytochrome P(1)-450 protein.
Length = 512
Score = 63.3 bits (147), Expect = 1e-09
Identities = 35/93 (37%), Positives = 59/93 (63%), Gaps = 2/93 (2%)
Frame = +2
Query: 110 RGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTG 289
+GL PPGP P++G++L++ K HL SQ+YG++L +R+GS VVV++G
Sbjct: 35 KGLKNPPGPWGWPLIGHMLTL------GKNPHLALSRMSQQYGDVLQIRIGSTPVVVLSG 88
Query: 290 IELIRE--VSNREVFEGRPDGFFYTMRSFGKKL 382
++ IR+ V + F+GRPD + +T+ S G+ +
Sbjct: 89 LDTIRQALVRQGDDFKGRPDLYTFTLISNGQSM 121
>K03191-1|AAA52139.1| 512|Homo sapiens CYP1A1 protein.
Length = 512
Score = 63.3 bits (147), Expect = 1e-09
Identities = 35/93 (37%), Positives = 59/93 (63%), Gaps = 2/93 (2%)
Frame = +2
Query: 110 RGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTG 289
+GL PPGP P++G++L++ K HL SQ+YG++L +R+GS VVV++G
Sbjct: 35 KGLKNPPGPWGWPLIGHMLTL------GKNPHLALSRMSQQYGDVLQIRIGSTPVVVLSG 88
Query: 290 IELIRE--VSNREVFEGRPDGFFYTMRSFGKKL 382
++ IR+ V + F+GRPD + +T+ S G+ +
Sbjct: 89 LDTIRQALVRQGDDFKGRPDLYTFTLISNGQSM 121
>EF094025-1|ABK41999.1| 512|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 1 protein.
Length = 512
Score = 63.3 bits (147), Expect = 1e-09
Identities = 35/93 (37%), Positives = 59/93 (63%), Gaps = 2/93 (2%)
Frame = +2
Query: 110 RGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTG 289
+GL PPGP P++G++L++ K HL SQ+YG++L +R+GS VVV++G
Sbjct: 35 KGLKNPPGPWGWPLIGHMLTL------GKNPHLALSRMSQQYGDVLQIRIGSTPVVVLSG 88
Query: 290 IELIRE--VSNREVFEGRPDGFFYTMRSFGKKL 382
++ IR+ V + F+GRPD + +T+ S G+ +
Sbjct: 89 LDTIRQALVRQGDDFKGRPDLYTFTLISNGQSM 121
>BC023019-1|AAH23019.1| 512|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 1 protein.
Length = 512
Score = 63.3 bits (147), Expect = 1e-09
Identities = 35/93 (37%), Positives = 59/93 (63%), Gaps = 2/93 (2%)
Frame = +2
Query: 110 RGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTG 289
+GL PPGP P++G++L++ K HL SQ+YG++L +R+GS VVV++G
Sbjct: 35 KGLKNPPGPWGWPLIGHMLTL------GKNPHLALSRMSQQYGDVLQIRIGSTPVVVLSG 88
Query: 290 IELIRE--VSNREVFEGRPDGFFYTMRSFGKKL 382
++ IR+ V + F+GRPD + +T+ S G+ +
Sbjct: 89 LDTIRQALVRQGDDFKGRPDLYTFTLISNGQSM 121
>AY310359-1|AAQ76692.1| 484|Homo sapiens cytochrome P450 1A1
variant protein.
Length = 484
Score = 63.3 bits (147), Expect = 1e-09
Identities = 35/93 (37%), Positives = 59/93 (63%), Gaps = 2/93 (2%)
Frame = +2
Query: 110 RGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTG 289
+GL PPGP P++G++L++ K HL SQ+YG++L +R+GS VVV++G
Sbjct: 35 KGLKNPPGPWGWPLIGHMLTL------GKNPHLALSRMSQQYGDVLQIRIGSTPVVVLSG 88
Query: 290 IELIRE--VSNREVFEGRPDGFFYTMRSFGKKL 382
++ IR+ V + F+GRPD + +T+ S G+ +
Sbjct: 89 LDTIRQALVRQGDDFKGRPDLYTFTLISNGQSM 121
>AM236046-1|CAJ84703.1| 229|Homo sapiens cytochrome P450 1A1
protein.
Length = 229
Score = 63.3 bits (147), Expect = 1e-09
Identities = 35/93 (37%), Positives = 59/93 (63%), Gaps = 2/93 (2%)
Frame = +2
Query: 110 RGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTG 289
+GL PPGP P++G++L++ K HL SQ+YG++L +R+GS VVV++G
Sbjct: 35 KGLKNPPGPWGWPLIGHMLTL------GKNPHLALSRMSQQYGDVLQIRIGSTPVVVLSG 88
Query: 290 IELIRE--VSNREVFEGRPDGFFYTMRSFGKKL 382
++ IR+ V + F+GRPD + +T+ S G+ +
Sbjct: 89 LDTIRQALVRQGDDFKGRPDLYTFTLISNGQSM 121
>AM233520-1|CAJ80723.1| 189|Homo sapiens cytochrome P450 1A1
protein.
Length = 189
Score = 63.3 bits (147), Expect = 1e-09
Identities = 35/93 (37%), Positives = 59/93 (63%), Gaps = 2/93 (2%)
Frame = +2
Query: 110 RGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTG 289
+GL PPGP P++G++L++ K HL SQ+YG++L +R+GS VVV++G
Sbjct: 35 KGLKNPPGPWGWPLIGHMLTL------GKNPHLALSRMSQQYGDVLQIRIGSTPVVVLSG 88
Query: 290 IELIRE--VSNREVFEGRPDGFFYTMRSFGKKL 382
++ IR+ V + F+GRPD + +T+ S G+ +
Sbjct: 89 LDTIRQALVRQGDDFKGRPDLYTFTLISNGQSM 121
>AM233519-1|CAJ80722.1| 189|Homo sapiens cytochrome P450 1A1
protein.
Length = 189
Score = 63.3 bits (147), Expect = 1e-09
Identities = 35/93 (37%), Positives = 59/93 (63%), Gaps = 2/93 (2%)
Frame = +2
Query: 110 RGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTG 289
+GL PPGP P++G++L++ K HL SQ+YG++L +R+GS VVV++G
Sbjct: 35 KGLKNPPGPWGWPLIGHMLTL------GKNPHLALSRMSQQYGDVLQIRIGSTPVVVLSG 88
Query: 290 IELIRE--VSNREVFEGRPDGFFYTMRSFGKKL 382
++ IR+ V + F+GRPD + +T+ S G+ +
Sbjct: 89 LDTIRQALVRQGDDFKGRPDLYTFTLISNGQSM 121
>AF253322-1|AAK25727.1| 512|Homo sapiens cytochrome P450 protein.
Length = 512
Score = 63.3 bits (147), Expect = 1e-09
Identities = 35/93 (37%), Positives = 59/93 (63%), Gaps = 2/93 (2%)
Frame = +2
Query: 110 RGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTG 289
+GL PPGP P++G++L++ K HL SQ+YG++L +R+GS VVV++G
Sbjct: 35 KGLKNPPGPWGWPLIGHMLTL------GKNPHLALSRMSQQYGDVLQIRIGSTPVVVLSG 88
Query: 290 IELIRE--VSNREVFEGRPDGFFYTMRSFGKKL 382
++ IR+ V + F+GRPD + +T+ S G+ +
Sbjct: 89 LDTIRQALVRQGDDFKGRPDLYTFTLISNGQSM 121
>AY871801-1|AAX62803.1| 483|Homo sapiens cytochrome P450 family 1
subfamily A polypeptide 1 protein.
Length = 483
Score = 62.9 bits (146), Expect = 1e-09
Identities = 35/93 (37%), Positives = 59/93 (63%), Gaps = 2/93 (2%)
Frame = +2
Query: 110 RGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTG 289
+GL PPGP P++G++L++ K HL SQ+YG++L +R+GS VVV++G
Sbjct: 35 KGLENPPGPWGWPLIGHMLTL------GKNPHLALSRMSQQYGDVLQIRIGSTPVVVLSG 88
Query: 290 IELIRE--VSNREVFEGRPDGFFYTMRSFGKKL 382
++ IR+ V + F+GRPD + +T+ S G+ +
Sbjct: 89 LDTIRQALVRQGDDFKGRPDLYTFTLISNGQSM 121
>X13930-1|CAA32118.1| 494|Homo sapiens protein ( Human CYP2A4 mRNA
for P-450 IIA4 protein. ).
Length = 494
Score = 62.5 bits (145), Expect = 2e-09
Identities = 68/260 (26%), Positives = 110/260 (42%), Gaps = 38/260 (14%)
Frame = +2
Query: 125 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTG----- 289
PPGPTPLP +GN L + E + S++YG + + LG VVV+ G
Sbjct: 34 PPGPTPLPFIGNYLQLNTEQMYNSLMKI-----SERYGPVFTIHLGPRRVVVLCGHDAVR 88
Query: 290 ---IELIREVSNRE-------VFEGRPDGF-------------FYTMRSFG-------KK 379
++ E S R VF+G F T+R FG ++
Sbjct: 89 EALVDQAEEFSGRGEQATFDWVFKGYGVVFSNGERAKQLRRFSIATLRDFGVGKRGIEER 148
Query: 380 LGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKLCSLVMRL 559
+ EE L+ G I T+ N++ +V G R+D +D+ L +++ +
Sbjct: 149 IQEEAGFLIDAHRGTGGANIDPTFFLSRTVSNVISSIVFGDRFDYKDKEFLSLLRMMLGI 208
Query: 560 FKLVDMSGGILN--FLPFLRHFV-PRLIGFTELQEIHNALHQYLREIIKEHQXNLQLGAP 730
F+ S G L F ++H P+ F LQ L ++ + ++ +Q L +P
Sbjct: 209 FQFTSTSTGQLYEMFSSVMKHLPGPQQQAFQLLQ----GLEDFIAKKVEHNQRTLDPNSP 264
Query: 731 KDVIDAFLIDMLESQXDKLT 790
+D ID+FLI M E + + T
Sbjct: 265 RDFIDSFLIRMQEEEKNPNT 284
>BC096255-1|AAH96255.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 62.5 bits (145), Expect = 2e-09
Identities = 68/260 (26%), Positives = 110/260 (42%), Gaps = 38/260 (14%)
Frame = +2
Query: 125 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTG----- 289
PPGPTPLP +GN L + E + S++YG + + LG VVV+ G
Sbjct: 34 PPGPTPLPFIGNYLQLNTEQMYNSLMKI-----SERYGPVFTIHLGPRRVVVLCGHDAVR 88
Query: 290 ---IELIREVSNRE-------VFEGRPDGF-------------FYTMRSFG-------KK 379
++ E S R VF+G F T+R FG ++
Sbjct: 89 EALVDQAEEFSGRGEQATFDWVFKGYGVVFSNGERAKQLRRFSIATLRDFGVGKRGIEER 148
Query: 380 LGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKLCSLVMRL 559
+ EE L+ G I T+ N++ +V G R+D +D+ L +++ +
Sbjct: 149 IQEEAGFLIDAHRGTGGANIDPTFFLSRTVSNVISSIVFGDRFDYKDKEFLSLLRMMLGI 208
Query: 560 FKLVDMSGGILN--FLPFLRHFV-PRLIGFTELQEIHNALHQYLREIIKEHQXNLQLGAP 730
F+ S G L F ++H P+ F LQ L ++ + ++ +Q L +P
Sbjct: 209 FQFTSTSTGQLYEMFSSVMKHLPGPQQQAFQLLQ----GLEDFIAKKVEHNQRTLDPNSP 264
Query: 731 KDVIDAFLIDMLESQXDKLT 790
+D ID+FLI M E + + T
Sbjct: 265 RDFIDSFLIRMQEEEKNPNT 284
>AF372573-1|AAL69652.1| 495|Homo sapiens cytochrome P450 2F1
protein.
Length = 495
Score = 62.5 bits (145), Expect = 2e-09
Identities = 72/271 (26%), Positives = 119/271 (43%), Gaps = 40/271 (14%)
Frame = +2
Query: 98 SRRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVV 277
S R +G PPGP PL I+GNLL + + L S++YG++ + LG VV
Sbjct: 23 SSRDKGKL-PPGPRPLSILGNLLLLCSQDMLTSLTKL-----SKEYGSMYTVHLGPRRVV 76
Query: 278 VVTGIELIRE--VSNREVFEGRPD--GFF-YT-----------------------MRSFG 373
V++G + ++E V E F GR D FF +T +R+FG
Sbjct: 77 VLSGYQAVKEALVDQGEEFSGRGDYPAFFNFTKGNGIAFSSGDRWKVLRQFSIQILRNFG 136
Query: 374 -------KKLGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLK 532
+++ EE L+ GEP + ++ NI+ ++ G R+D +D+RL
Sbjct: 137 MGKRSIEERILEEGSFLLAELRKTEGEPFDPTFVLSRSVSNIICSVLFGSRFDYDDERLL 196
Query: 533 KLCSLVMRLFKLVDMSGGILNFL-----PFLRHFVPRLIGFTELQEIHNALHQYLREIIK 697
+ L+ F+++ G L + P L +VP + + L + +
Sbjct: 197 TIIRLINDNFQIMSSPWGELYDILDPRFPSLLDWVPG--PHQRIFQNFKCLRDLIAHSVH 254
Query: 698 EHQXNLQLGAPKDVIDAFLIDMLESQXDKLT 790
+HQ +L +P+D I FL M E + D L+
Sbjct: 255 DHQASLDPRSPRDFIHCFLTKMAEEKEDPLS 285
>X13897-1|CAA32097.1| 489|Homo sapiens protein ( Human mRNA for
cytochrome P-450IIA. ).
Length = 489
Score = 61.7 bits (143), Expect = 3e-09
Identities = 70/268 (26%), Positives = 114/268 (42%), Gaps = 38/268 (14%)
Frame = +2
Query: 101 RRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 280
R+++G PPGPTPLP +GN L + E + S++YG + + LG VVV
Sbjct: 22 RKNKGKL-PPGPTPLPFIGNYLQLNTEQMYNSLMKI-----SERYGPVFTIHLGPRRVVV 75
Query: 281 VTG--------IELIREVSNRE-------VFEGRPDGF-------------FYTMRSFG- 373
+ G ++ E S R VF+G F T+R FG
Sbjct: 76 LCGHDAVREALVDQAEEFSGRGEQATFDWVFKGYGVVFSNGERAKQLRRFSIATLRDFGV 135
Query: 374 ------KKLGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKK 535
+++ EE L+ G I T+ N++ +V G R+D +D+
Sbjct: 136 GKRGIEERIQEEAGFLIDALRGTGGANIDPTFFLSRTVSNVISSIVFGDRFDYKDKEFLS 195
Query: 536 LCSLVMRLFKLVDMSGGILN--FLPFLRHFV-PRLIGFTELQEIHNALHQYLREIIKEHQ 706
L +++ +F+ S G L F ++H P+ F LQ L ++ + ++ Q
Sbjct: 196 LLRMMLGIFQFTSTSTGQLYEMFSSVMKHLPGPQQQAFQLLQ----GLEDFIAKKVEHKQ 251
Query: 707 XNLQLGAPKDVIDAFLIDMLESQXDKLT 790
L +P+D ID+FLI M E + + T
Sbjct: 252 RTLDPNSPRDFIDSFLIRMQEEEKNPNT 279
>M33318-1|AAA52067.1| 494|Homo sapiens CYP2A protein.
Length = 494
Score = 61.7 bits (143), Expect = 3e-09
Identities = 68/260 (26%), Positives = 110/260 (42%), Gaps = 38/260 (14%)
Frame = +2
Query: 125 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTG----- 289
PPGPTPLP +GN L + E + S++YG + + LG VVV+ G
Sbjct: 34 PPGPTPLPFIGNYLQLNTEQMYNSLMKI-----SERYGPVFTIHLGPRRVVVLCGHDAVR 88
Query: 290 ---IELIREVSNRE-------VFEGRPDGF-------------FYTMRSFG-------KK 379
++ E S R VF+G F T+R FG ++
Sbjct: 89 EALVDQAEEFSGRGEQATFDWVFKGYGVVFSNGERAKQLRRFSIATLRDFGVGKRGIEER 148
Query: 380 LGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKLCSLVMRL 559
+ EE L+ G I T+ N++ +V G R+D +D+ L +++ +
Sbjct: 149 IQEEAGFLIDALRGTGGANIDPTFFLSRTVSNVISSIVFGDRFDYKDKEFLSLLRMMLGI 208
Query: 560 FKLVDMSGGILN--FLPFLRHFV-PRLIGFTELQEIHNALHQYLREIIKEHQXNLQLGAP 730
F+ S G L F ++H P+ F LQ L ++ + ++ +Q L +P
Sbjct: 209 FQFTSTSTGQLYEMFSSVMKHLPGPQQQAFQLLQ----GLEDFIAKKVEHNQRTLDPNSP 264
Query: 731 KDVIDAFLIDMLESQXDKLT 790
+D ID+FLI M E + + T
Sbjct: 265 RDFIDSFLIRMQEEEKNPNT 284
>BC096256-1|AAH96256.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 61.7 bits (143), Expect = 3e-09
Identities = 68/260 (26%), Positives = 110/260 (42%), Gaps = 38/260 (14%)
Frame = +2
Query: 125 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTG----- 289
PPGPTPLP +GN L + E + S++YG + + LG VVV+ G
Sbjct: 34 PPGPTPLPFIGNYLQLNTEQMYNSLMKI-----SERYGPVFTIHLGPRRVVVLCGHDAVR 88
Query: 290 ---IELIREVSNRE-------VFEGRPDGF-------------FYTMRSFG-------KK 379
++ E S R VF+G F T+R FG ++
Sbjct: 89 EALVDQAEEFSGRGEQATFDWVFKGYGVVFSNGERAKQLRRFSIATLRDFGVGKRGIEER 148
Query: 380 LGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKLCSLVMRL 559
+ EE L+ G I T+ N++ +V G R+D +D+ L +++ +
Sbjct: 149 IQEEAGFLIDALRGTGGANIDPTFFLSRTVSNVISSIVFGDRFDYKDKEFLSLLRMMLGI 208
Query: 560 FKLVDMSGGILN--FLPFLRHFV-PRLIGFTELQEIHNALHQYLREIIKEHQXNLQLGAP 730
F+ S G L F ++H P+ F LQ L ++ + ++ +Q L +P
Sbjct: 209 FQFTSTSTGQLYEMFSSVMKHLPGPQQQAFQLLQ----GLEDFIAKKVEHNQRTLDPNSP 264
Query: 731 KDVIDAFLIDMLESQXDKLT 790
+D ID+FLI M E + + T
Sbjct: 265 RDFIDSFLIRMQEEEKNPNT 284
>BC096254-1|AAH96254.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 61.7 bits (143), Expect = 3e-09
Identities = 68/260 (26%), Positives = 110/260 (42%), Gaps = 38/260 (14%)
Frame = +2
Query: 125 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTG----- 289
PPGPTPLP +GN L + E + S++YG + + LG VVV+ G
Sbjct: 34 PPGPTPLPFIGNYLQLNTEQMYNSLMKI-----SERYGPVFTIHLGPRRVVVLCGHDAVR 88
Query: 290 ---IELIREVSNRE-------VFEGRPDGF-------------FYTMRSFG-------KK 379
++ E S R VF+G F T+R FG ++
Sbjct: 89 EALVDQAEEFSGRGEQATFDWVFKGYGVVFSNGERAKQLRRFSIATLRDFGVGKRGIEER 148
Query: 380 LGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKLCSLVMRL 559
+ EE L+ G I T+ N++ +V G R+D +D+ L +++ +
Sbjct: 149 IQEEAGFLIDALRGTGGANIDPTFFLSRTVSNVISSIVFGDRFDYKDKEFLSLLRMMLGI 208
Query: 560 FKLVDMSGGILN--FLPFLRHFV-PRLIGFTELQEIHNALHQYLREIIKEHQXNLQLGAP 730
F+ S G L F ++H P+ F LQ L ++ + ++ +Q L +P
Sbjct: 209 FQFTSTSTGQLYEMFSSVMKHLPGPQQQAFQLLQ----GLEDFIAKKVEHNQRTLDPNSP 264
Query: 731 KDVIDAFLIDMLESQXDKLT 790
+D ID+FLI M E + + T
Sbjct: 265 RDFIDSFLIRMQEEEKNPNT 284
>BC096253-1|AAH96253.3| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 61.7 bits (143), Expect = 3e-09
Identities = 68/260 (26%), Positives = 110/260 (42%), Gaps = 38/260 (14%)
Frame = +2
Query: 125 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTG----- 289
PPGPTPLP +GN L + E + S++YG + + LG VVV+ G
Sbjct: 34 PPGPTPLPFIGNYLQLNTEQMYNSLMKI-----SERYGPVFTIHLGPRRVVVLCGHDAVR 88
Query: 290 ---IELIREVSNRE-------VFEGRPDGF-------------FYTMRSFG-------KK 379
++ E S R VF+G F T+R FG ++
Sbjct: 89 EALVDQAEEFSGRGEQATFDWVFKGYGVVFSNGERAKQLRRFSIATLRDFGVGKRGIEER 148
Query: 380 LGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKLCSLVMRL 559
+ EE L+ G I T+ N++ +V G R+D +D+ L +++ +
Sbjct: 149 IQEEAGFLIDALRGTGGANIDPTFFLSRTVSNVISSIVFGDRFDYKDKEFLSLLRMMLGI 208
Query: 560 FKLVDMSGGILN--FLPFLRHFV-PRLIGFTELQEIHNALHQYLREIIKEHQXNLQLGAP 730
F+ S G L F ++H P+ F LQ L ++ + ++ +Q L +P
Sbjct: 209 FQFTSTSTGQLYEMFSSVMKHLPGPQQQAFQLLQ----GLEDFIAKKVEHNQRTLDPNSP 264
Query: 731 KDVIDAFLIDMLESQXDKLT 790
+D ID+FLI M E + + T
Sbjct: 265 RDFIDSFLIRMQEEEKNPNT 284
>AF182275-1|AAF13600.1| 494|Homo sapiens cytochrome P450-2A6
protein.
Length = 494
Score = 61.7 bits (143), Expect = 3e-09
Identities = 68/260 (26%), Positives = 110/260 (42%), Gaps = 38/260 (14%)
Frame = +2
Query: 125 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTG----- 289
PPGPTPLP +GN L + E + S++YG + + LG VVV+ G
Sbjct: 34 PPGPTPLPFIGNYLQLNTEQMYNSLMKI-----SERYGPVFTIHLGPRRVVVLCGHDAVR 88
Query: 290 ---IELIREVSNRE-------VFEGRPDGF-------------FYTMRSFG-------KK 379
++ E S R VF+G F T+R FG ++
Sbjct: 89 EALVDQAEEFSGRGEQATFDWVFKGYGVVFSNGERAKQLRRFSIATLRDFGVGKRGIEER 148
Query: 380 LGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKLCSLVMRL 559
+ EE L+ G I T+ N++ +V G R+D +D+ L +++ +
Sbjct: 149 IQEEAGFLIDALRGTGGANIDPTFFLSRTVSNVISSIVFGDRFDYKDKEFLSLLRMMLGI 208
Query: 560 FKLVDMSGGILN--FLPFLRHFV-PRLIGFTELQEIHNALHQYLREIIKEHQXNLQLGAP 730
F+ S G L F ++H P+ F LQ L ++ + ++ +Q L +P
Sbjct: 209 FQFTSTSTGQLYEMFSSVMKHLPGPQQQAFQLLQ----GLEDFIAKKVEHNQRTLDPNSP 264
Query: 731 KDVIDAFLIDMLESQXDKLT 790
+D ID+FLI M E + + T
Sbjct: 265 RDFIDSFLIRMQEEEKNPNT 284
>U22027-1|AAB40518.1| 494|Homo sapiens cytochrome P450 protein.
Length = 494
Score = 61.3 bits (142), Expect = 4e-09
Identities = 68/260 (26%), Positives = 112/260 (43%), Gaps = 38/260 (14%)
Frame = +2
Query: 125 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTG----- 289
PPGPTPLP +GN L + E + S++YG + + LG VVV+ G
Sbjct: 34 PPGPTPLPFIGNYLQLNTEQMYNSLMKI-----SERYGPVFTIHLGPRRVVVLCGHDAVR 88
Query: 290 ---IELIREVSNRE-------VFEGRPDGF-------------FYTMRSFG-------KK 379
++ E S R VF+G F T+R FG ++
Sbjct: 89 EALVDQAEEFSGRGEQATFDWVFKGYGVVFSNGERAKQLLRFAIATLRDFGVGKRGIEER 148
Query: 380 LGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKLCSLVMRL 559
+ EE L++ + G I T+ N++ +V G R+D +D+ L +++ +
Sbjct: 149 IQEESGFLIEAIRSTHGANIDPTFFLSRTVSNVISSIVFGDRFDYKDKEFLSLLRMMLGI 208
Query: 560 FKLVDMSGGILN--FLPFLRHFV-PRLIGFTELQEIHNALHQYLREIIKEHQXNLQLGAP 730
F+ S G L F ++H P+ F LQ L ++ + ++ +Q L +P
Sbjct: 209 FQFTSTSTGQLYEMFSSVMKHLPGPQQQAFQLLQ----GLEDFIAKKVEHNQRTLDPNSP 264
Query: 731 KDVIDAFLIDMLESQXDKLT 790
+D ID+FLI M E + + T
Sbjct: 265 RDFIDSFLIRMQEEEKNPNT 284
>U37143-1|AAC50370.2| 502|Homo sapiens cytochrome P450
monooxygenase CYP2J2 protein.
Length = 502
Score = 58.4 bits (135), Expect = 3e-08
Identities = 31/69 (44%), Positives = 41/69 (59%)
Frame = +2
Query: 101 RRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 280
+R R YPPGP LP +GN V F+ HL Q + +KYGNL L LG I+ V+
Sbjct: 36 KRRRPKNYPPGPWRLPFLGNFFLV-----DFEQSHLEVQLFVKKYGNLFSLELGDISAVL 90
Query: 281 VTGIELIRE 307
+TG+ LI+E
Sbjct: 91 ITGLPLIKE 99
>BC032594-1|AAH32594.1| 502|Homo sapiens cytochrome P450, family 2,
subfamily J, polypeptide 2 protein.
Length = 502
Score = 58.4 bits (135), Expect = 3e-08
Identities = 31/69 (44%), Positives = 41/69 (59%)
Frame = +2
Query: 101 RRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 280
+R R YPPGP LP +GN V F+ HL Q + +KYGNL L LG I+ V+
Sbjct: 36 KRRRPKNYPPGPWRLPFLGNFFLV-----DFEQSHLEVQLFVKKYGNLFSLELGDISAVL 90
Query: 281 VTGIELIRE 307
+TG+ LI+E
Sbjct: 91 ITGLPLIKE 99
>AY426985-1|AAQ93356.1| 502|Homo sapiens cytochrome P450, family 2,
subfamily J, polypeptide 2 protein.
Length = 502
Score = 58.4 bits (135), Expect = 3e-08
Identities = 31/69 (44%), Positives = 41/69 (59%)
Frame = +2
Query: 101 RRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 280
+R R YPPGP LP +GN V F+ HL Q + +KYGNL L LG I+ V+
Sbjct: 36 KRRRPKNYPPGPWRLPFLGNFFLV-----DFEQSHLEVQLFVKKYGNLFSLELGDISAVL 90
Query: 281 VTGIELIRE 307
+TG+ LI+E
Sbjct: 91 ITGLPLIKE 99
>AF272142-1|AAM44456.1| 502|Homo sapiens cytochrome P450 protein.
Length = 502
Score = 58.4 bits (135), Expect = 3e-08
Identities = 31/69 (44%), Positives = 41/69 (59%)
Frame = +2
Query: 101 RRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 280
+R R YPPGP LP +GN V F+ HL Q + +KYGNL L LG I+ V+
Sbjct: 36 KRRRPKNYPPGPWRLPFLGNFFLV-----DFEQSHLEVQLFVKKYGNLFSLELGDISAVL 90
Query: 281 VTGIELIRE 307
+TG+ LI+E
Sbjct: 91 ITGLPLIKE 99
>AF144566-1|AAD30164.1| 339|Homo sapiens cytochrome P450
epoxygenase protein.
Length = 339
Score = 58.4 bits (135), Expect = 3e-08
Identities = 31/69 (44%), Positives = 41/69 (59%)
Frame = +2
Query: 101 RRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 280
+R R YPPGP LP +GN V F+ HL Q + +KYGNL L LG I+ V+
Sbjct: 5 KRRRPKNYPPGPWRLPFLGNFFLV-----DFEQSHLEVQLFVKKYGNLFSLELGDISAVL 59
Query: 281 VTGIELIRE 307
+TG+ LI+E
Sbjct: 60 ITGLPLIKE 68
>AB080265-1|BAB85489.1| 502|Homo sapiens cytochrome P450 2J2
protein.
Length = 502
Score = 58.4 bits (135), Expect = 3e-08
Identities = 31/69 (44%), Positives = 41/69 (59%)
Frame = +2
Query: 101 RRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 280
+R R YPPGP LP +GN V F+ HL Q + +KYGNL L LG I+ V+
Sbjct: 36 KRRRPKNYPPGPWRLPFLGNFFLV-----DFEQSHLEVQLFVKKYGNLFSLELGDISAVL 90
Query: 281 VTGIELIRE 307
+TG+ LI+E
Sbjct: 91 ITGLPLIKE 99
>S46963-1|AAB23864.2| 477|Homo sapiens cytochrome P-450 protein.
Length = 477
Score = 57.6 bits (133), Expect = 5e-08
Identities = 66/267 (24%), Positives = 113/267 (42%), Gaps = 40/267 (14%)
Frame = +2
Query: 125 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIR 304
PPGPTPLP++GN+L + + +L S+ YG + L G +VV+ G E ++
Sbjct: 17 PPGPTPLPVIGNILQIGIKDISKSLTNL-----SKVYGPVFTLYFGLKPIVVLHGYEAVK 71
Query: 305 --------EVSNREVF---EGRPDGF-----------------FYTMRSFGK-------K 379
E S R +F E GF T+R+FG +
Sbjct: 72 EALIDLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIRRFSLMTLRNFGMGKRSIEDR 131
Query: 380 LGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKLCSLVMRL 559
+ EE LV+ P + N++ ++ KR+D +DQ+ L +
Sbjct: 132 VQEEARCLVEELRKTKASPCDPTFILGCAPCNVICSIIFHKRFDYKDQQFLNLMEKLNEN 191
Query: 560 FKLVDMSGGIL--NFLPFLRHFVPRLIGFTELQEIHNALHQYLREIIKEHQXNLQLGAPK 733
K++ + NF P + +F +L + + Y+ E +KEHQ ++ + P+
Sbjct: 192 IKILSSPWIQICNNFSPIIDYFPGT---HNKLLKNVAFMKSYILEKVKEHQESMDMNNPQ 248
Query: 734 DVIDAFLIDM---LESQXDKLTLDDLQ 805
D ID FL+ M +Q + T++ L+
Sbjct: 249 DFIDCFLMKMEKEKHNQPSEFTIESLE 275
>M29873-1|AAA52143.1| 377|Homo sapiens CYP2B protein.
Length = 377
Score = 57.6 bits (133), Expect = 5e-08
Identities = 40/138 (28%), Positives = 72/138 (52%), Gaps = 4/138 (2%)
Frame = +2
Query: 362 RSFGKKLGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKLC 541
RS +++ +E + L++ G + +FH NI+ ++ GKR+ +DQ K
Sbjct: 140 RSVEERIQDEAQCLIEELRKSKGALVDPTFLFHSITANIICSIIFGKRFHYQDQEFLKTL 199
Query: 542 SLVMRLFKLV-DMSGGILN-FLPFLRHF--VPRLIGFTELQEIHNALHQYLREIIKEHQX 709
+L + F L+ +S + F FL++F R + + LQEI NA Y+ +++H+
Sbjct: 200 NLFCQSFLLISSISSQLFELFSGFLKYFPGAHRQV-YKNLQEI-NA---YIGHSVEKHRE 254
Query: 710 NLQLGAPKDVIDAFLIDM 763
L AP+D+ID +L+ M
Sbjct: 255 TLDPSAPRDLIDTYLLHM 272
Score = 52.0 bits (119), Expect = 2e-06
Identities = 31/73 (42%), Positives = 43/73 (58%), Gaps = 2/73 (2%)
Frame = +2
Query: 125 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIR 304
PPGP PLP++GNLL + + R L + +KYG++ + LG VV++ G+E IR
Sbjct: 31 PPGPRPLPLLGNLLQM--DRRGLLKSFL---RFREKYGDVFTVHLGPRPVVMLCGVEAIR 85
Query: 305 E--VSNREVFEGR 337
E V N E F GR
Sbjct: 86 EALVDNAEAFSGR 98
>M21939-1|AAA52158.1| 485|Homo sapiens CYP2C protein.
Length = 485
Score = 57.6 bits (133), Expect = 5e-08
Identities = 66/267 (24%), Positives = 113/267 (42%), Gaps = 40/267 (14%)
Frame = +2
Query: 125 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIR 304
PPGPTPLP++GN+L + + +L S+ YG + L G +VV+ G E ++
Sbjct: 25 PPGPTPLPVIGNILQIGIKDISKSLTNL-----SKVYGPVFTLYFGLKPIVVLHGYEAVK 79
Query: 305 --------EVSNREVF---EGRPDGF-----------------FYTMRSFGK-------K 379
E S R +F E GF T+R+FG +
Sbjct: 80 EALIDLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIRRFSLMTLRNFGMGKRSIEDR 139
Query: 380 LGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKLCSLVMRL 559
+ EE LV+ P + N++ ++ KR+D +DQ+ L +
Sbjct: 140 VQEEARCLVEELRKTKASPCDPTFILGCAPCNVICSIIFHKRFDYKDQQFLNLMEKLNEN 199
Query: 560 FKLVDMSGGIL--NFLPFLRHFVPRLIGFTELQEIHNALHQYLREIIKEHQXNLQLGAPK 733
K++ + NF P + +F +L + + Y+ E +KEHQ ++ + P+
Sbjct: 200 IKILSSPWIQICNNFSPIIDYFPGT---HNKLLKNVAFMKSYILEKVKEHQESMDMNNPQ 256
Query: 734 DVIDAFLIDM---LESQXDKLTLDDLQ 805
D ID FL+ M +Q + T++ L+
Sbjct: 257 DFIDCFLMKMEKEKHNQPSEFTIESLE 283
>M15331-1|AAA52157.1| 485|Homo sapiens CYP2C protein.
Length = 485
Score = 57.6 bits (133), Expect = 5e-08
Identities = 66/267 (24%), Positives = 113/267 (42%), Gaps = 40/267 (14%)
Frame = +2
Query: 125 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIR 304
PPGPTPLP++GN+L + + +L S+ YG + L G +VV+ G E ++
Sbjct: 25 PPGPTPLPVIGNILQIGIKDISKSLTNL-----SKVYGPVFTLYFGLKPIVVLHGYEAVK 79
Query: 305 --------EVSNREVF---EGRPDGF-----------------FYTMRSFGK-------K 379
E S R +F E GF T+R+FG +
Sbjct: 80 EALIDLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIRRFSLMTLRNFGMGKRSIEDR 139
Query: 380 LGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKLCSLVMRL 559
+ EE LV+ P + N++ ++ KR+D +DQ+ L +
Sbjct: 140 VQEEARCLVEELRKTKASPCDPTFILGCAPCNVICSIIFHKRFDYKDQQFLNLMEKLNEN 199
Query: 560 FKLVDMSGGIL--NFLPFLRHFVPRLIGFTELQEIHNALHQYLREIIKEHQXNLQLGAPK 733
K++ + NF P + +F +L + + Y+ E +KEHQ ++ + P+
Sbjct: 200 IKILSSPWIQICNNFSPIIDYFPGT---HNKLLKNVAFMKSYILEKVKEHQESMDMNNPQ 256
Query: 734 DVIDAFLIDM---LESQXDKLTLDDLQ 805
D ID FL+ M +Q + T++ L+
Sbjct: 257 DFIDCFLMKMEKEKHNQPSEFTIESLE 283
>D00173-1|BAA00123.1| 487|Homo sapiens cytochrome P-450 protein.
Length = 487
Score = 57.6 bits (133), Expect = 5e-08
Identities = 66/267 (24%), Positives = 113/267 (42%), Gaps = 40/267 (14%)
Frame = +2
Query: 125 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIR 304
PPGPTPLP++GN+L + + +L S+ YG + L G +VV+ G E ++
Sbjct: 27 PPGPTPLPVIGNILQIGIKDISKSLTNL-----SKVYGPVFTLYFGLKPIVVLHGYEAVK 81
Query: 305 --------EVSNREVF---EGRPDGF-----------------FYTMRSFGK-------K 379
E S R +F E GF T+R+FG +
Sbjct: 82 EALIDLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIRRFSLMTLRNFGMGKRSIEDR 141
Query: 380 LGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKLCSLVMRL 559
+ EE LV+ P + N++ ++ KR+D +DQ+ L +
Sbjct: 142 VQEEARCLVEELRKTKASPCDPTFILGCAPCNVICSIIFHKRFDYKDQQFLNLMEKLNEN 201
Query: 560 FKLVDMSGGIL--NFLPFLRHFVPRLIGFTELQEIHNALHQYLREIIKEHQXNLQLGAPK 733
K++ + NF P + +F +L + + Y+ E +KEHQ ++ + P+
Sbjct: 202 IKILSSPWIQICNNFSPIIDYFPGT---HNKLLKNVAFMKSYILEKVKEHQESMDMNNPQ 258
Query: 734 DVIDAFLIDM---LESQXDKLTLDDLQ 805
D ID FL+ M +Q + T++ L+
Sbjct: 259 DFIDCFLMKMEKEKHNQPSEFTIESLE 285
>BC125054-1|AAI25055.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 9 protein.
Length = 490
Score = 57.6 bits (133), Expect = 5e-08
Identities = 66/267 (24%), Positives = 113/267 (42%), Gaps = 40/267 (14%)
Frame = +2
Query: 125 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIR 304
PPGPTPLP++GN+L + + +L S+ YG + L G +VV+ G E ++
Sbjct: 30 PPGPTPLPVIGNILQIGIKDISKSLTNL-----SKVYGPVFTLYFGLKPIVVLHGYEAVK 84
Query: 305 --------EVSNREVF---EGRPDGF-----------------FYTMRSFGK-------K 379
E S R +F E GF T+R+FG +
Sbjct: 85 EALIDLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIRRFSLMTLRNFGMGKRSIEDR 144
Query: 380 LGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKLCSLVMRL 559
+ EE LV+ P + N++ ++ KR+D +DQ+ L +
Sbjct: 145 VQEEARCLVEELRKTKASPCDPTFILGCAPCNVICSIIFHKRFDYKDQQFLNLMEKLNEN 204
Query: 560 FKLVDMSGGIL--NFLPFLRHFVPRLIGFTELQEIHNALHQYLREIIKEHQXNLQLGAPK 733
K++ + NF P + +F +L + + Y+ E +KEHQ ++ + P+
Sbjct: 205 IKILSSPWIQICNNFSPIIDYFPGT---HNKLLKNVAFMKSYILEKVKEHQESMDMNNPQ 261
Query: 734 DVIDAFLIDM---LESQXDKLTLDDLQ 805
D ID FL+ M +Q + T++ L+
Sbjct: 262 DFIDCFLMKMEKEKHNQPSEFTIESLE 288
>BC041174-1|AAH41174.1| 377|Homo sapiens CYP2B7P1 protein protein.
Length = 377
Score = 57.6 bits (133), Expect = 5e-08
Identities = 40/138 (28%), Positives = 72/138 (52%), Gaps = 4/138 (2%)
Frame = +2
Query: 362 RSFGKKLGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKLC 541
RS +++ +E + L++ G + +FH NI+ ++ GKR+ +DQ K
Sbjct: 140 RSVEERIQDEAQCLIEELRKSKGALVDPTFLFHSITANIICSIIFGKRFHYQDQEFLKTL 199
Query: 542 SLVMRLFKLV-DMSGGILN-FLPFLRHF--VPRLIGFTELQEIHNALHQYLREIIKEHQX 709
+L + F L+ +S + F FL++F R + + LQEI NA Y+ +++H+
Sbjct: 200 NLFCQSFLLISSISSQLFELFSGFLKYFPGAHRQV-YKNLQEI-NA---YIGHSVEKHRE 254
Query: 710 NLQLGAPKDVIDAFLIDM 763
L AP+D+ID +L+ M
Sbjct: 255 TLDPSAPRDLIDTYLLHM 272
Score = 52.0 bits (119), Expect = 2e-06
Identities = 31/73 (42%), Positives = 43/73 (58%), Gaps = 2/73 (2%)
Frame = +2
Query: 125 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIR 304
PPGP PLP++GNLL + + R L + +KYG++ + LG VV++ G+E IR
Sbjct: 31 PPGPRPLPLLGNLLQM--DRRGLLKSFL---RFREKYGDVFTVHLGPRPVVMLCGVEAIR 85
Query: 305 E--VSNREVFEGR 337
E V N E F GR
Sbjct: 86 EALVDNAEAFSGR 98
>AY702706-1|AAT94065.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 9 protein.
Length = 490
Score = 57.6 bits (133), Expect = 5e-08
Identities = 66/267 (24%), Positives = 113/267 (42%), Gaps = 40/267 (14%)
Frame = +2
Query: 125 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIR 304
PPGPTPLP++GN+L + + +L S+ YG + L G +VV+ G E ++
Sbjct: 30 PPGPTPLPVIGNILQIGIKDISKSLTNL-----SKVYGPVFTLYFGLKPIVVLHGYEAVK 84
Query: 305 --------EVSNREVF---EGRPDGF-----------------FYTMRSFGK-------K 379
E S R +F E GF T+R+FG +
Sbjct: 85 EALIDLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIRRFSLMTLRNFGMGKRSIEDR 144
Query: 380 LGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKLCSLVMRL 559
+ EE LV+ P + N++ ++ KR+D +DQ+ L +
Sbjct: 145 VQEEARCLVEELRKTKASPCDPTFILGCAPCNVICSIIFHKRFDYKDQQFLNLMEKLNEN 204
Query: 560 FKLVDMSGGIL--NFLPFLRHFVPRLIGFTELQEIHNALHQYLREIIKEHQXNLQLGAPK 733
K++ + NF P + +F +L + + Y+ E +KEHQ ++ + P+
Sbjct: 205 IKILSSPWIQICNNFSPIIDYFPGT---HNKLLKNVAFMKSYILEKVKEHQESMDMNNPQ 261
Query: 734 DVIDAFLIDM---LESQXDKLTLDDLQ 805
D ID FL+ M +Q + T++ L+
Sbjct: 262 DFIDCFLMKMEKEKHNQPSEFTIESLE 288
>AY341248-1|AAP88931.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 9 protein.
Length = 490
Score = 57.6 bits (133), Expect = 5e-08
Identities = 66/267 (24%), Positives = 113/267 (42%), Gaps = 40/267 (14%)
Frame = +2
Query: 125 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIR 304
PPGPTPLP++GN+L + + +L S+ YG + L G +VV+ G E ++
Sbjct: 30 PPGPTPLPVIGNILQIGIKDISKSLTNL-----SKVYGPVFTLYFGLKPIVVLHGYEAVK 84
Query: 305 --------EVSNREVF---EGRPDGF-----------------FYTMRSFGK-------K 379
E S R +F E GF T+R+FG +
Sbjct: 85 EALIDLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIRRFSLMTLRNFGMGKRSIEDR 144
Query: 380 LGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKLCSLVMRL 559
+ EE LV+ P + N++ ++ KR+D +DQ+ L +
Sbjct: 145 VQEEARCLVEELRKTKASPCDPTFILGCAPCNVICSIIFHKRFDYKDQQFLNLMEKLNEN 204
Query: 560 FKLVDMSGGIL--NFLPFLRHFVPRLIGFTELQEIHNALHQYLREIIKEHQXNLQLGAPK 733
K++ + NF P + +F +L + + Y+ E +KEHQ ++ + P+
Sbjct: 205 IKILSSPWIQICNNFSPIIDYFPGT---HNKLLKNVAFMKSYILEKVKEHQESMDMNNPQ 261
Query: 734 DVIDAFLIDM---LESQXDKLTLDDLQ 805
D ID FL+ M +Q + T++ L+
Sbjct: 262 DFIDCFLMKMEKEKHNQPSEFTIESLE 288
>AL359672-1|CAH71303.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 9 protein.
Length = 490
Score = 57.6 bits (133), Expect = 5e-08
Identities = 66/267 (24%), Positives = 113/267 (42%), Gaps = 40/267 (14%)
Frame = +2
Query: 125 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIR 304
PPGPTPLP++GN+L + + +L S+ YG + L G +VV+ G E ++
Sbjct: 30 PPGPTPLPVIGNILQIGIKDISKSLTNL-----SKVYGPVFTLYFGLKPIVVLHGYEAVK 84
Query: 305 --------EVSNREVF---EGRPDGF-----------------FYTMRSFGK-------K 379
E S R +F E GF T+R+FG +
Sbjct: 85 EALIDLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIRRFSLMTLRNFGMGKRSIEDR 144
Query: 380 LGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKLCSLVMRL 559
+ EE LV+ P + N++ ++ KR+D +DQ+ L +
Sbjct: 145 VQEEARCLVEELRKTKASPCDPTFILGCAPCNVICSIIFHKRFDYKDQQFLNLMEKLNEN 204
Query: 560 FKLVDMSGGIL--NFLPFLRHFVPRLIGFTELQEIHNALHQYLREIIKEHQXNLQLGAPK 733
K++ + NF P + +F +L + + Y+ E +KEHQ ++ + P+
Sbjct: 205 IKILSSPWIQICNNFSPIIDYFPGT---HNKLLKNVAFMKSYILEKVKEHQESMDMNNPQ 261
Query: 734 DVIDAFLIDM---LESQXDKLTLDDLQ 805
D ID FL+ M +Q + T++ L+
Sbjct: 262 DFIDCFLMKMEKEKHNQPSEFTIESLE 288
>AF182276-1|AAF13601.1| 493|Homo sapiens cytochrome P450-2E1
protein.
Length = 493
Score = 56.8 bits (131), Expect = 9e-08
Identities = 59/256 (23%), Positives = 109/256 (42%), Gaps = 37/256 (14%)
Frame = +2
Query: 107 HRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVT 286
H PPGP PLPI+GNL + + K + +Q++G + L +GS +VV+
Sbjct: 27 HSSWNLPPGPFPLPIIGNLFQL-----ELKNIPKSFTRLAQRFGPVFTLYVGSQRMVVMH 81
Query: 287 GIELIRE--VSNREVFEGRPD----------GFFY---------------TMRSFG---- 373
G + ++E + ++ F GR D G + T+R++G
Sbjct: 82 GYKAVKEALLDYKDEFSGRGDLPAFHAHRDRGIIFNNGPTWKDIRRFSLTTLRNYGMGKQ 141
Query: 374 ---KKLGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKLCS 544
++ E L++ G+P + N++ ++ K +D D++ +L
Sbjct: 142 GNESRIQREAHFLLEALRKTQGQPFDPTFLIGCAPCNVIADILFRKHFDYNDEKFLRLMY 201
Query: 545 LVMRLFKLVDMSG-GILNFLPFLRHFVPRLIGFTELQEIHNA--LHQYLREIIKEHQXNL 715
L F L+ + N P H++P + + I N + +Y+ E +KEH +L
Sbjct: 202 LFNENFHLLSTPWLQLYNNFPSFLHYLPG----SHRKAIKNVAEVKEYVSERVKEHHQSL 257
Query: 716 QLGAPKDVIDAFLIDM 763
P+D+ D L++M
Sbjct: 258 DPNCPRDLTDCLLVEM 273
>L16880-1|AAD13466.1| 273|Homo sapiens cytochrome P-450 2C protein.
Length = 273
Score = 56.4 bits (130), Expect = 1e-07
Identities = 63/250 (25%), Positives = 105/250 (42%), Gaps = 37/250 (14%)
Frame = +2
Query: 125 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIR 304
PPGPTPLP++GN+L + + +L S+ YG + L G +VV+ G E ++
Sbjct: 30 PPGPTPLPVIGNILQIGIKDISKSLTNL-----SKVYGPVFTLYFGLKPIVVLHGYEAVK 84
Query: 305 --------EVSNREVF---EGRPDGF-----------------FYTMRSFGK-------K 379
E S R +F E GF T+R+FG +
Sbjct: 85 EALIDLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIRRFSLMTLRNFGMGKRSIEDR 144
Query: 380 LGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKLCSLVMRL 559
+ EE LV+ P + N++ ++ KR+D +DQ+ L +
Sbjct: 145 VQEEARCLVEELRKTKASPCDPTFILGCAPCNVICSIIFHKRFDYKDQQFLNLMEKLNEN 204
Query: 560 FKLVDMSGGIL--NFLPFLRHFVPRLIGFTELQEIHNALHQYLREIIKEHQXNLQLGAPK 733
K++ + NF P + +F +L + + Y+ E +KEHQ ++ + P+
Sbjct: 205 IKILSSPWIQICNNFSPIIDYFPGT---HNKLLKNVAFMKSYILEKVKEHQESMDMNNPQ 261
Query: 734 DVIDAFLIDM 763
D ID FL+ M
Sbjct: 262 DFIDCFLMKM 271
>J02843-1|AAA52155.1| 493|Homo sapiens protein ( Human cytochrome
P450IIE1 (ethanol-inducible) gene, complete cds. ).
Length = 493
Score = 56.4 bits (130), Expect = 1e-07
Identities = 59/256 (23%), Positives = 109/256 (42%), Gaps = 37/256 (14%)
Frame = +2
Query: 107 HRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVT 286
H PPGP PLPI+GNL + + K + +Q++G + L +GS +VV+
Sbjct: 27 HSSWNLPPGPFPLPIIGNLFQL-----ELKNIPKSFTRLAQRFGPVFTLYVGSQRMVVMH 81
Query: 287 GIELIRE--VSNREVFEGRPD----------GFFY---------------TMRSFG---- 373
G + ++E + ++ F GR D G + T+R++G
Sbjct: 82 GYKAVKEALLDYKDEFSGRGDLPAFHAHRDRGIIFNNGPTWKDIRRFSLTTLRNYGMGKQ 141
Query: 374 ---KKLGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKLCS 544
++ E L++ G+P + N++ ++ K +D D++ +L
Sbjct: 142 GNESRIQREAHFLLEALRKTQGQPFDPTFLIGCAPCNVIADILFRKHFDYNDEKFLRLMY 201
Query: 545 LVMRLFKLVDMSG-GILNFLPFLRHFVPRLIGFTELQEIHNA--LHQYLREIIKEHQXNL 715
L F L+ + N P H++P + + I N + +Y+ E +KEH +L
Sbjct: 202 LFNENFHLLSTPWLQLYNNFPSFLHYLPG----SHRKVIKNVAEVKEYVSERVKEHHQSL 257
Query: 716 QLGAPKDVIDAFLIDM 763
P+D+ D L++M
Sbjct: 258 DPNCPRDLTDCLLVEM 273
>J02625-1|AAA35743.1| 493|Homo sapiens protein ( Human cytochrome
P-450j mRNA, complete cds. ).
Length = 493
Score = 56.4 bits (130), Expect = 1e-07
Identities = 59/256 (23%), Positives = 109/256 (42%), Gaps = 37/256 (14%)
Frame = +2
Query: 107 HRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVT 286
H PPGP PLPI+GNL + + K + +Q++G + L +GS +VV+
Sbjct: 27 HSSWNLPPGPFPLPIIGNLFQL-----ELKNIPKSFTRLAQRFGPVFTLYVGSQRMVVMH 81
Query: 287 GIELIRE--VSNREVFEGRPD----------GFFY---------------TMRSFG---- 373
G + ++E + ++ F GR D G + T+R++G
Sbjct: 82 GYKAVKEALLDYKDEFSGRGDLPAFHAHRDRGIIFNNGPTWKDIRRFSLTTLRNYGMGKQ 141
Query: 374 ---KKLGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKLCS 544
++ E L++ G+P + N++ ++ K +D D++ +L
Sbjct: 142 GNESRIQREAHFLLEALRKTQGQPFDPTFLIGCAPCNVIADILFRKHFDYNDEKFLRLMY 201
Query: 545 LVMRLFKLVDMSG-GILNFLPFLRHFVPRLIGFTELQEIHNA--LHQYLREIIKEHQXNL 715
L F L+ + N P H++P + + I N + +Y+ E +KEH +L
Sbjct: 202 LFNENFHLLSTPWLQLYNNFPSFLHYLPG----SHRKVIKNVAEVKEYVSERVKEHHQSL 257
Query: 716 QLGAPKDVIDAFLIDM 763
P+D+ D L++M
Sbjct: 258 DPNCPRDLTDCLLVEM 273
>DQ515958-1|ABF47105.1| 493|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 1 protein.
Length = 493
Score = 56.4 bits (130), Expect = 1e-07
Identities = 59/256 (23%), Positives = 109/256 (42%), Gaps = 37/256 (14%)
Frame = +2
Query: 107 HRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVT 286
H PPGP PLPI+GNL + + K + +Q++G + L +GS +VV+
Sbjct: 27 HSSWNLPPGPFPLPIIGNLFQL-----ELKNIPKSFTRLAQRFGPVFTLYVGSQRMVVMH 81
Query: 287 GIELIRE--VSNREVFEGRPD----------GFFY---------------TMRSFG---- 373
G + ++E + ++ F GR D G + T+R++G
Sbjct: 82 GYKAVKEALLDYKDEFSGRGDLPAFHAHRDRGIIFNNGPTWKDIRRFSLTTLRNYGMGKQ 141
Query: 374 ---KKLGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKLCS 544
++ E L++ G+P + N++ ++ K +D D++ +L
Sbjct: 142 GNESRIQREAHFLLEALRKTQGQPFDPTFLIGCAPCNVIADILFRKHFDYNDEKFLRLMY 201
Query: 545 LVMRLFKLVDMSG-GILNFLPFLRHFVPRLIGFTELQEIHNA--LHQYLREIIKEHQXNL 715
L F L+ + N P H++P + + I N + +Y+ E +KEH +L
Sbjct: 202 LFNENFHLLSTPWLQLYNNFPSFLHYLPG----SHRKVIKNVAEVKEYVSERVKEHHQSL 257
Query: 716 QLGAPKDVIDAFLIDM 763
P+D+ D L++M
Sbjct: 258 DPNCPRDLTDCLLVEM 273
>DQ149222-1|AAZ77710.1| 493|Homo sapiens cytochrome P450 2E1
protein.
Length = 493
Score = 56.4 bits (130), Expect = 1e-07
Identities = 59/256 (23%), Positives = 109/256 (42%), Gaps = 37/256 (14%)
Frame = +2
Query: 107 HRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVT 286
H PPGP PLPI+GNL + + K + +Q++G + L +GS +VV+
Sbjct: 27 HSSWNLPPGPFPLPIIGNLFQL-----ELKNIPKSFTRLAQRFGPVFTLYVGSQRMVVMH 81
Query: 287 GIELIRE--VSNREVFEGRPD----------GFFY---------------TMRSFG---- 373
G + ++E + ++ F GR D G + T+R++G
Sbjct: 82 GYKAVKEALLDYKDEFSGRGDLPAFHAHRDRGIIFNNGPTWKDIRRFSLTTLRNYGMGKQ 141
Query: 374 ---KKLGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKLCS 544
++ E L++ G+P + N++ ++ K +D D++ +L
Sbjct: 142 GNESRIQREAHFLLEALRKTQGQPFDPTFLIGCAPCNVIADILFRKHFDYNDEKFLRLMY 201
Query: 545 LVMRLFKLVDMSG-GILNFLPFLRHFVPRLIGFTELQEIHNA--LHQYLREIIKEHQXNL 715
L F L+ + N P H++P + + I N + +Y+ E +KEH +L
Sbjct: 202 LFNENFHLLSTPWLQLYNNFPSFLHYLPG----SHRKVIKNVAEVKEYVSERVKEHHQSL 257
Query: 716 QLGAPKDVIDAFLIDM 763
P+D+ D L++M
Sbjct: 258 DPNCPRDLADCLLVEM 273
>BC067435-1|AAH67435.1| 493|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 1 protein.
Length = 493
Score = 56.4 bits (130), Expect = 1e-07
Identities = 59/256 (23%), Positives = 109/256 (42%), Gaps = 37/256 (14%)
Frame = +2
Query: 107 HRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVT 286
H PPGP PLPI+GNL + + K + +Q++G + L +GS +VV+
Sbjct: 27 HSSWNLPPGPFPLPIIGNLFQL-----ELKNIPKSFTRLAQRFGPVFTLYVGSQRMVVMH 81
Query: 287 GIELIRE--VSNREVFEGRPD----------GFFY---------------TMRSFG---- 373
G + ++E + ++ F GR D G + T+R++G
Sbjct: 82 GYKAVKEALLDYKDEFSGRGDLPAFHAHRDRGIIFNNGPAWKDIRRFSLTTLRNYGMGKQ 141
Query: 374 ---KKLGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKLCS 544
++ E L++ G+P + N++ ++ K +D D++ +L
Sbjct: 142 GNESRIQREAHFLLEALRKTQGQPFDPTFLIGCAPCNVIADILFRKHFDYNDEKFLRLMY 201
Query: 545 LVMRLFKLVDMSG-GILNFLPFLRHFVPRLIGFTELQEIHNA--LHQYLREIIKEHQXNL 715
L F L+ + N P H++P + + I N + +Y+ E +KEH +L
Sbjct: 202 LFNENFHLLSTPWLQLYNNFPSFLHYLPG----SHRKVIKNVAEVKEYVSERVKEHHQSL 257
Query: 716 QLGAPKDVIDAFLIDM 763
P+D+ D L++M
Sbjct: 258 DPNCPRDLTDCLLVEM 273
>AL161645-2|CAH70047.1| 493|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 1 protein.
Length = 493
Score = 56.4 bits (130), Expect = 1e-07
Identities = 59/256 (23%), Positives = 109/256 (42%), Gaps = 37/256 (14%)
Frame = +2
Query: 107 HRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVT 286
H PPGP PLPI+GNL + + K + +Q++G + L +GS +VV+
Sbjct: 27 HSSWNLPPGPFPLPIIGNLFQL-----ELKNIPKSFTRLAQRFGPVFTLYVGSQRMVVMH 81
Query: 287 GIELIRE--VSNREVFEGRPD----------GFFY---------------TMRSFG---- 373
G + ++E + ++ F GR D G + T+R++G
Sbjct: 82 GYKAVKEALLDYKDEFSGRGDLPAFHAHRDRGIIFNNGPTWKDIRRFSLTTLRNYGMGKQ 141
Query: 374 ---KKLGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKLCS 544
++ E L++ G+P + N++ ++ K +D D++ +L
Sbjct: 142 GNESRIQREAHFLLEALRKTQGQPFDPTFLIGCAPCNVIADILFRKHFDYNDEKFLRLMY 201
Query: 545 LVMRLFKLVDMSG-GILNFLPFLRHFVPRLIGFTELQEIHNA--LHQYLREIIKEHQXNL 715
L F L+ + N P H++P + + I N + +Y+ E +KEH +L
Sbjct: 202 LFNENFHLLSTPWLQLYNNFPSFLHYLPG----SHRKVIKNVAEVKEYVSERVKEHHQSL 257
Query: 716 QLGAPKDVIDAFLIDM 763
P+D+ D L++M
Sbjct: 258 DPNCPRDLTDCLLVEM 273
>BC067433-1|AAH67433.1| 493|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 1 protein.
Length = 493
Score = 56.0 bits (129), Expect = 1e-07
Identities = 59/256 (23%), Positives = 109/256 (42%), Gaps = 37/256 (14%)
Frame = +2
Query: 107 HRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVT 286
H PPGP PLPI+GNL + + K + +Q++G + L +GS +VV+
Sbjct: 27 HSSWNLPPGPFPLPIIGNLFQL-----ELKNIPKSFTRLAQRFGPVFTLCVGSQRMVVMH 81
Query: 287 GIELIRE--VSNREVFEGRPD----------GFFY---------------TMRSFG---- 373
G + ++E + ++ F GR D G + T+R++G
Sbjct: 82 GYKAVKEALLDYKDEFSGRGDLPAFHAHRDRGIIFNNGPTWKDIRRFSLTTLRNYGMGKQ 141
Query: 374 ---KKLGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKLCS 544
++ E L++ G+P + N++ ++ K +D D++ +L
Sbjct: 142 GNESRIQREAHFLLEALRKTQGQPFDPTFLIGCAPCNVIADILFRKHFDYNDEKFLRLMY 201
Query: 545 LVMRLFKLVDMSG-GILNFLPFLRHFVPRLIGFTELQEIHNA--LHQYLREIIKEHQXNL 715
L F L+ + N P H++P + + I N + +Y+ E +KEH +L
Sbjct: 202 LFNENFHLLSTPWLQLYNNFPSFLHYLPG----SHRKVIKNVAEVKEYVSERVKEHHQSL 257
Query: 716 QLGAPKDVIDAFLIDM 763
P+D+ D L++M
Sbjct: 258 DPNCPRDLTDCLLVEM 273
>AY513608-1|AAR90939.1| 494|Homo sapiens cytochrome P450 2A13
variant 5 protein.
Length = 494
Score = 56.0 bits (129), Expect = 1e-07
Identities = 41/152 (26%), Positives = 70/152 (46%), Gaps = 3/152 (1%)
Frame = +2
Query: 344 GFFYTMRSFGKKLGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQ 523
GF R +++ EE L++ G I T+ N++ +V G R+D ED+
Sbjct: 137 GFGVGKRGIEERIQEEAGFLIEALRGTHGANIDPTFFLSRTVSNVISSIVFGDRFDYEDK 196
Query: 524 RLKKLCSLVMRLFKLVDMSGGIL--NFLPFLRHFV-PRLIGFTELQEIHNALHQYLREII 694
L +++ F+ S G L F ++H P+ F ELQ L ++ + +
Sbjct: 197 EFLSLLRMMLGSFQFTATSTGQLYEMFSSVMKHLPGPQQQAFKELQ----GLEDFIAKKV 252
Query: 695 KEHQXNLQLGAPKDVIDAFLIDMLESQXDKLT 790
+ +Q L +P+D ID+FLI M E + + T
Sbjct: 253 EHNQRTLDPNSPRDFIDSFLIRMQEEEKNPNT 284
Score = 48.0 bits (109), Expect = 4e-05
Identities = 36/113 (31%), Positives = 55/113 (48%), Gaps = 6/113 (5%)
Frame = +2
Query: 101 RRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 280
R+ RG PPGPTPLP +GN L + E + S++YG + + LG VVV
Sbjct: 27 RKSRGKL-PPGPTPLPFIGNYLQLNTEQMYNSLMKI-----SERYGPVFTIHLGPRRVVV 80
Query: 281 VTGIELIRE--VSNREVFEGRPD--GFFYTMRSFGKKL--GEECEALVQLRLA 421
+ G + ++E V E F GR + F + + +G GE + L + +A
Sbjct: 81 LCGHDAVKEALVDQAEEFSGRGEQATFDWLFKGYGVAFSNGERAKQLRRFSIA 133
>AF084225-1|AAD13753.1| 462|Homo sapiens cytochrome P450 2E1
protein.
Length = 462
Score = 56.0 bits (129), Expect = 1e-07
Identities = 58/250 (23%), Positives = 108/250 (43%), Gaps = 37/250 (14%)
Frame = +2
Query: 125 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIR 304
PPGP PLPI+GNL + + K + +Q++G + L +GS +VV+ G + ++
Sbjct: 2 PPGPFPLPIIGNLFQL-----ELKNIPKSFTRLAQRFGPVFTLYVGSQRMVVMHGYKAVK 56
Query: 305 E--VSNREVFEGRPD----------GFFY---------------TMRSFG-------KKL 382
E + ++ F GR D G + T+R++G ++
Sbjct: 57 EALLDYKDEFSGRGDLPAFHAHRDRGIIFNNGPTWKDIRRFSLTTLRNYGMGKQGNESRI 116
Query: 383 GEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKLCSLVMRLF 562
E L++ G+P + N++ ++ K +D D++ +L L F
Sbjct: 117 QREAHFLLEALRKTQGQPFDPTFLIGCAPCNVIADILFRKHFDYNDEKFLRLMYLFNENF 176
Query: 563 KLVDMSG-GILNFLPFLRHFVPRLIGFTELQEIHNA--LHQYLREIIKEHQXNLQLGAPK 733
L+ + N P H++P + + I N + +Y+ E +KEH +L P+
Sbjct: 177 HLLSTPWLQLYNNFPSFLHYLPG----SHRKVIKNVAEVKEYVSERVKEHHQSLDPNCPR 232
Query: 734 DVIDAFLIDM 763
D+ D L++M
Sbjct: 233 DLTDCLLVEM 242
>U22028-1|AAB40519.1| 494|Homo sapiens cytochrome P450 protein.
Length = 494
Score = 55.6 bits (128), Expect = 2e-07
Identities = 41/152 (26%), Positives = 69/152 (45%), Gaps = 3/152 (1%)
Frame = +2
Query: 344 GFFYTMRSFGKKLGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQ 523
GF R +++ EE L+ G I T+ N++ +V G R+D ED+
Sbjct: 137 GFGVGKRGIEERIQEEAGFLIDALRGTHGANIDPTFFLSRTVSNVISSIVFGDRFDYEDK 196
Query: 524 RLKKLCSLVMRLFKLVDMSGGIL--NFLPFLRHFV-PRLIGFTELQEIHNALHQYLREII 694
L +++ F+ S G L F ++H P+ F ELQ L ++ + +
Sbjct: 197 EFLSLLRMMLGRFQFTGTSTGQLYEMFSSVMKHLPGPQQQAFKELQ----GLEDFIAKKV 252
Query: 695 KEHQXNLQLGAPKDVIDAFLIDMLESQXDKLT 790
+ +Q L +P+D ID+FLI M E + + T
Sbjct: 253 EHNQRTLDPNSPRDFIDSFLIRMQEEEKNPNT 284
Score = 48.0 bits (109), Expect = 4e-05
Identities = 36/113 (31%), Positives = 55/113 (48%), Gaps = 6/113 (5%)
Frame = +2
Query: 101 RRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 280
R+ RG PPGPTPLP +GN L + E + S++YG + + LG VVV
Sbjct: 27 RKSRGKL-PPGPTPLPFIGNYLQLNTEQMYNSLMKI-----SERYGPVFTIHLGPRRVVV 80
Query: 281 VTGIELIRE--VSNREVFEGRPD--GFFYTMRSFGKKL--GEECEALVQLRLA 421
+ G + ++E V E F GR + F + + +G GE + L + +A
Sbjct: 81 LCGHDAVKEALVDQAEEFSGRGEQATFDWLFKGYGVAFSNGERAKQLRRFSIA 133
>AY513609-1|AAR90940.1| 494|Homo sapiens cytochrome P450 2A13
variant 6 protein.
Length = 494
Score = 55.2 bits (127), Expect = 3e-07
Identities = 41/152 (26%), Positives = 69/152 (45%), Gaps = 3/152 (1%)
Frame = +2
Query: 344 GFFYTMRSFGKKLGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQ 523
GF R +++ EE L+ G I T+ N++ +V G R+D ED+
Sbjct: 137 GFGVGKRGIEERIQEEAGFLIDALRGTHGANIDPTFFLSRTVSNVISSIVFGDRFDYEDK 196
Query: 524 RLKKLCSLVMRLFKLVDMSGGIL--NFLPFLRHFV-PRLIGFTELQEIHNALHQYLREII 694
L +++ F+ S G L F ++H P+ F ELQ L ++ + +
Sbjct: 197 EFLSLLRMMLGSFQFTATSTGQLYEMFSSVMKHLPGPQQQAFKELQ----GLEDFIAKKV 252
Query: 695 KEHQXNLQLGAPKDVIDAFLIDMLESQXDKLT 790
+ +Q L +P+D ID+FLI M E + + T
Sbjct: 253 EHNQRTLDPNSPRDFIDSFLIRMQEEEKNPNT 284
Score = 48.0 bits (109), Expect = 4e-05
Identities = 36/113 (31%), Positives = 55/113 (48%), Gaps = 6/113 (5%)
Frame = +2
Query: 101 RRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 280
R+ RG PPGPTPLP +GN L + E + S++YG + + LG VVV
Sbjct: 27 RKSRGKL-PPGPTPLPFIGNYLQLNTEQMYNSLMKI-----SERYGPVFTIHLGPRRVVV 80
Query: 281 VTGIELIRE--VSNREVFEGRPD--GFFYTMRSFGKKL--GEECEALVQLRLA 421
+ G + ++E V E F GR + F + + +G GE + L + +A
Sbjct: 81 LCGHDAVKEALVDQAEEFSGRGEQATFDWLFKGYGVAFSNGERAKQLRRFSIA 133
>AY513606-1|AAR90937.1| 494|Homo sapiens cytochrome P450 2A13
variant 3 protein.
Length = 494
Score = 55.2 bits (127), Expect = 3e-07
Identities = 41/152 (26%), Positives = 69/152 (45%), Gaps = 3/152 (1%)
Frame = +2
Query: 344 GFFYTMRSFGKKLGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQ 523
GF R +++ EE L+ G I T+ N++ +V G R+D ED+
Sbjct: 137 GFGVGKRGIEERIQEEAGFLIDALRGTHGANIDPTFFLSRTVSNVISSIVFGDRFDYEDK 196
Query: 524 RLKKLCSLVMRLFKLVDMSGGIL--NFLPFLRHFV-PRLIGFTELQEIHNALHQYLREII 694
L +++ F+ S G L F ++H P+ F ELQ L ++ + +
Sbjct: 197 EFLSLLRMMLGSFQFTATSTGQLYEMFSSVMKHLPGPQQQAFKELQ----GLEDFIAKKV 252
Query: 695 KEHQXNLQLGAPKDVIDAFLIDMLESQXDKLT 790
+ +Q L +P+D ID+FLI M E + + T
Sbjct: 253 EHNQRTLDPNSPRDFIDSFLIRMQEEEKNPNT 284
Score = 48.0 bits (109), Expect = 4e-05
Identities = 36/113 (31%), Positives = 55/113 (48%), Gaps = 6/113 (5%)
Frame = +2
Query: 101 RRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 280
R+ RG PPGPTPLP +GN L + E + S++YG + + LG VVV
Sbjct: 27 RKSRGKL-PPGPTPLPFIGNYLQLNTEQMYNSLMKI-----SERYGPVFTIHLGPRRVVV 80
Query: 281 VTGIELIRE--VSNREVFEGRPD--GFFYTMRSFGKKL--GEECEALVQLRLA 421
+ G + ++E V E F GR + F + + +G GE + L + +A
Sbjct: 81 LCGHDAVKEALVDQAEEFSGRGEQATFDWLFKGYGVAFSNGERAKQLRRFSIA 133
>AY513605-1|AAR90936.1| 494|Homo sapiens cytochrome P450 2A13
variant 2 protein.
Length = 494
Score = 55.2 bits (127), Expect = 3e-07
Identities = 41/152 (26%), Positives = 69/152 (45%), Gaps = 3/152 (1%)
Frame = +2
Query: 344 GFFYTMRSFGKKLGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQ 523
GF R +++ EE L+ G I T+ N++ +V G R+D ED+
Sbjct: 137 GFGVGKRGIEERIQEEAGFLIDALRGTHGANIDPTFFLSRTVSNVISSIVFGDRFDYEDK 196
Query: 524 RLKKLCSLVMRLFKLVDMSGGIL--NFLPFLRHFV-PRLIGFTELQEIHNALHQYLREII 694
L +++ F+ S G L F ++H P+ F ELQ L ++ + +
Sbjct: 197 EFLSLLRMMLGSFQFTATSTGQLYEMFSSVMKHLPGPQQQAFKELQ----GLEDFIAKKV 252
Query: 695 KEHQXNLQLGAPKDVIDAFLIDMLESQXDKLT 790
+ +Q L +P+D ID+FLI M E + + T
Sbjct: 253 EHNQRTLDPNSPRDFIDSFLIRMQEEEKNPNT 284
Score = 48.0 bits (109), Expect = 4e-05
Identities = 36/113 (31%), Positives = 55/113 (48%), Gaps = 6/113 (5%)
Frame = +2
Query: 101 RRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 280
R+ RG PPGPTPLP +GN L + E + S++YG + + LG VVV
Sbjct: 27 RKSRGKL-PPGPTPLPFIGNYLQLNTEQMYNSLMKI-----SERYGPVFTIHLGPRRVVV 80
Query: 281 VTGIELIRE--VSNREVFEGRPD--GFFYTMRSFGKKL--GEECEALVQLRLA 421
+ G + ++E V E F GR + F + + +G GE + L + +A
Sbjct: 81 LCGHDAVKEALVDQAEEFSGRGEQATFDWLFKGYGVAFSNGERAKQLRRFSIA 133
>AY513604-1|AAR90935.1| 494|Homo sapiens cytochrome P450 2A13
variant 1 protein.
Length = 494
Score = 55.2 bits (127), Expect = 3e-07
Identities = 41/152 (26%), Positives = 69/152 (45%), Gaps = 3/152 (1%)
Frame = +2
Query: 344 GFFYTMRSFGKKLGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQ 523
GF R +++ EE L+ G I T+ N++ +V G R+D ED+
Sbjct: 137 GFGVGKRGIEERIQEEAGFLIDALRGTHGANIDPTFFLSRTVSNVISSIVFGDRFDYEDK 196
Query: 524 RLKKLCSLVMRLFKLVDMSGGIL--NFLPFLRHFV-PRLIGFTELQEIHNALHQYLREII 694
L +++ F+ S G L F ++H P+ F ELQ L ++ + +
Sbjct: 197 EFLSLLRMMLGSFQFTATSTGQLYEMFSSVMKHLPGPQQQAFKELQ----GLEDFIAKKV 252
Query: 695 KEHQXNLQLGAPKDVIDAFLIDMLESQXDKLT 790
+ +Q L +P+D ID+FLI M E + + T
Sbjct: 253 EHNQRTLDPNSPRDFIDSFLIRMQEEEKNPNT 284
Score = 48.0 bits (109), Expect = 4e-05
Identities = 36/113 (31%), Positives = 55/113 (48%), Gaps = 6/113 (5%)
Frame = +2
Query: 101 RRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 280
R+ RG PPGPTPLP +GN L + E + S++YG + + LG VVV
Sbjct: 27 RKSRGKL-PPGPTPLPFIGNYLQLNTEQMYNSLMKI-----SERYGPVFTIHLGPRRVVV 80
Query: 281 VTGIELIRE--VSNREVFEGRPD--GFFYTMRSFGKKL--GEECEALVQLRLA 421
+ G + ++E V E F GR + F + + +G GE + L + +A
Sbjct: 81 LCGHDAVKEALVDQAEEFSGRGEQATFDWLFKGYGVAFSNGERAKQLRRFSIA 133
>AF209774-1|AAG35775.1| 494|Homo sapiens cytochrome P450 2A13
protein.
Length = 494
Score = 55.2 bits (127), Expect = 3e-07
Identities = 41/152 (26%), Positives = 69/152 (45%), Gaps = 3/152 (1%)
Frame = +2
Query: 344 GFFYTMRSFGKKLGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQ 523
GF R +++ EE L+ G I T+ N++ +V G R+D ED+
Sbjct: 137 GFGVGKRGIEERIQEEAGFLIDALRGTHGANIDPTFFLSRTVSNVISSIVFGDRFDYEDK 196
Query: 524 RLKKLCSLVMRLFKLVDMSGGIL--NFLPFLRHFV-PRLIGFTELQEIHNALHQYLREII 694
L +++ F+ S G L F ++H P+ F ELQ L ++ + +
Sbjct: 197 EFLSLLRMMLGSFQFTATSTGQLYEMFSSVMKHLPGPQQQAFKELQ----GLEDFIAKKV 252
Query: 695 KEHQXNLQLGAPKDVIDAFLIDMLESQXDKLT 790
+ +Q L +P+D ID+FLI M E + + T
Sbjct: 253 EHNQRTLDPNSPRDFIDSFLIRMQEEEKNPNT 284
Score = 48.0 bits (109), Expect = 4e-05
Identities = 36/113 (31%), Positives = 55/113 (48%), Gaps = 6/113 (5%)
Frame = +2
Query: 101 RRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 280
R+ RG PPGPTPLP +GN L + E + S++YG + + LG VVV
Sbjct: 27 RKSRGKL-PPGPTPLPFIGNYLQLNTEQMYNSLMKI-----SERYGPVFTIHLGPRRVVV 80
Query: 281 VTGIELIRE--VSNREVFEGRPD--GFFYTMRSFGKKL--GEECEALVQLRLA 421
+ G + ++E V E F GR + F + + +G GE + L + +A
Sbjct: 81 LCGHDAVKEALVDQAEEFSGRGEQATFDWLFKGYGVAFSNGERAKQLRRFSIA 133
>M61854-1|AAB59426.1| 490|Homo sapiens cytochrome protein.
Length = 490
Score = 53.6 bits (123), Expect = 8e-07
Identities = 67/265 (25%), Positives = 111/265 (41%), Gaps = 39/265 (14%)
Frame = +2
Query: 125 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTG----- 289
PPGPTPLP++GN+L + + +L S+ YG + L G +VV+ G
Sbjct: 30 PPGPTPLPVIGNILQIDIKDVSKSLTNL-----SKIYGPVFTLYFGLERMVVLHGYEVVK 84
Query: 290 ---IELIREVSNREVF---EGRPDGF-----------------FYTMRSFGK-------K 379
I+L E S R F E GF T+R+FG +
Sbjct: 85 EALIDLGEEFSGRGHFPLAERANRGFGIVFSNGKRWKEIRRFSLMTLRNFGMGKRSIEDR 144
Query: 380 LGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKLCSLVMRL 559
+ EE LV+ P + N++ ++ KR+D +DQ+ L +
Sbjct: 145 VQEEARCLVEELRKTKASPCDPTFILGCAPCNVICSIIFQKRFDYKDQQFLNLMEKLNEN 204
Query: 560 FKLVDMSG-GILNFLPFLRHFVPRLIGFTELQEIHNALHQYLREIIKEHQXNLQLGAPKD 736
++V I N P + + P +L + + + E +KEHQ ++ + P+D
Sbjct: 205 IRIVSTPWIQICNNFPTIIDYFPGT--HNKLLKNLAFMESDILEKVKEHQESMDINNPRD 262
Query: 737 VIDAFLIDM---LESQXDKLTLDDL 802
ID FLI M ++Q + T+++L
Sbjct: 263 FIDCFLIKMEKEKQNQQSEFTIENL 287
>AY796203-1|AAV41877.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 19 protein.
Length = 490
Score = 53.6 bits (123), Expect = 8e-07
Identities = 67/265 (25%), Positives = 111/265 (41%), Gaps = 39/265 (14%)
Frame = +2
Query: 125 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTG----- 289
PPGPTPLP++GN+L + + +L S+ YG + L G +VV+ G
Sbjct: 30 PPGPTPLPVIGNILQIDIKDVSKSLTNL-----SKIYGPVFTLYFGLERMVVLHGYEVVK 84
Query: 290 ---IELIREVSNREVF---EGRPDGF-----------------FYTMRSFGK-------K 379
I+L E S R F E GF T+R+FG +
Sbjct: 85 EALIDLGEEFSGRGHFPLAERANRGFGIVFSNGKRWKEIRRFSLMTLRNFGMGKRSIEDR 144
Query: 380 LGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKLCSLVMRL 559
+ EE LV+ P + N++ ++ KR+D +DQ+ L +
Sbjct: 145 VQEEARCLVEELRKTKASPCDPTFILGCAPCNVICSIIFQKRFDYKDQQFLNLMEKLNEN 204
Query: 560 FKLVDMSG-GILNFLPFLRHFVPRLIGFTELQEIHNALHQYLREIIKEHQXNLQLGAPKD 736
++V I N P + + P +L + + + E +KEHQ ++ + P+D
Sbjct: 205 IRIVSTPWIQICNNFPTIIDYFPGT--HNKLLKNLAFMESDILEKVKEHQESMDINNPRD 262
Query: 737 VIDAFLIDM---LESQXDKLTLDDL 802
ID FLI M ++Q + T+++L
Sbjct: 263 FIDCFLIKMEKEKQNQQSEFTIENL 287
>AL583836-2|CAH74068.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 19 protein.
Length = 490
Score = 53.6 bits (123), Expect = 8e-07
Identities = 67/265 (25%), Positives = 111/265 (41%), Gaps = 39/265 (14%)
Frame = +2
Query: 125 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTG----- 289
PPGPTPLP++GN+L + + +L S+ YG + L G +VV+ G
Sbjct: 30 PPGPTPLPVIGNILQIDIKDVSKSLTNL-----SKIYGPVFTLYFGLERMVVLHGYEVVK 84
Query: 290 ---IELIREVSNREVF---EGRPDGF-----------------FYTMRSFGK-------K 379
I+L E S R F E GF T+R+FG +
Sbjct: 85 EALIDLGEEFSGRGHFPLAERANRGFGIVFSNGKRWKEIRRFSLMTLRNFGMGKRSIEDR 144
Query: 380 LGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKLCSLVMRL 559
+ EE LV+ P + N++ ++ KR+D +DQ+ L +
Sbjct: 145 VQEEARCLVEELRKTKASPCDPTFILGCAPCNVICSIIFQKRFDYKDQQFLNLMEKLNEN 204
Query: 560 FKLVDMSG-GILNFLPFLRHFVPRLIGFTELQEIHNALHQYLREIIKEHQXNLQLGAPKD 736
++V I N P + + P +L + + + E +KEHQ ++ + P+D
Sbjct: 205 IRIVSTPWIQICNNFPTIIDYFPGT--HNKLLKNLAFMESDILEKVKEHQESMDINNPRD 262
Query: 737 VIDAFLIDM---LESQXDKLTLDDL 802
ID FLI M ++Q + T+++L
Sbjct: 263 FIDCFLIKMEKEKQNQQSEFTIENL 287
>AL133513-2|CAH73444.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 19 protein.
Length = 490
Score = 53.6 bits (123), Expect = 8e-07
Identities = 67/265 (25%), Positives = 111/265 (41%), Gaps = 39/265 (14%)
Frame = +2
Query: 125 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTG----- 289
PPGPTPLP++GN+L + + +L S+ YG + L G +VV+ G
Sbjct: 30 PPGPTPLPVIGNILQIDIKDVSKSLTNL-----SKIYGPVFTLYFGLERMVVLHGYEVVK 84
Query: 290 ---IELIREVSNREVF---EGRPDGF-----------------FYTMRSFGK-------K 379
I+L E S R F E GF T+R+FG +
Sbjct: 85 EALIDLGEEFSGRGHFPLAERANRGFGIVFSNGKRWKEIRRFSLMTLRNFGMGKRSIEDR 144
Query: 380 LGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKLCSLVMRL 559
+ EE LV+ P + N++ ++ KR+D +DQ+ L +
Sbjct: 145 VQEEARCLVEELRKTKASPCDPTFILGCAPCNVICSIIFQKRFDYKDQQFLNLMEKLNEN 204
Query: 560 FKLVDMSG-GILNFLPFLRHFVPRLIGFTELQEIHNALHQYLREIIKEHQXNLQLGAPKD 736
++V I N P + + P +L + + + E +KEHQ ++ + P+D
Sbjct: 205 IRIVSTPWIQICNNFPTIIDYFPGT--HNKLLKNLAFMESDILEKVKEHQESMDINNPRD 262
Query: 737 VIDAFLIDM---LESQXDKLTLDDL 802
ID FLI M ++Q + T+++L
Sbjct: 263 FIDCFLIKMEKEKQNQQSEFTIENL 287
>Z00036-1|CAA77335.1| 515|Homo sapiens protein ( Human mRNA for
cytochrome P-3-450. ).
Length = 515
Score = 52.4 bits (120), Expect = 2e-06
Identities = 32/93 (34%), Positives = 56/93 (60%), Gaps = 2/93 (2%)
Frame = +2
Query: 110 RGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTG 289
+GL PP P P++G++L++ K HL SQ+YG++L +R+GS V+V++
Sbjct: 37 KGLKSPPEPWGWPLLGHVLTL------GKNPHLALSRMSQRYGDVLQIRIGSTPVLVLSR 90
Query: 290 IELIRE--VSNREVFEGRPDGFFYTMRSFGKKL 382
++ IR+ V + F+GRPD + T+ + G+ L
Sbjct: 91 LDTIRQALVRQGDDFKGRPDLYTSTLITDGQSL 123
>M55053-1|AAA52146.1| 515|Homo sapiens cytochrome P3-450 protein.
Length = 515
Score = 52.4 bits (120), Expect = 2e-06
Identities = 32/93 (34%), Positives = 56/93 (60%), Gaps = 2/93 (2%)
Frame = +2
Query: 110 RGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTG 289
+GL PP P P++G++L++ K HL SQ+YG++L +R+GS V+V++
Sbjct: 37 KGLKSPPEPWGWPLLGHVLTL------GKNPHLALSRMSQRYGDVLQIRIGSTPVLVLSR 90
Query: 290 IELIRE--VSNREVFEGRPDGFFYTMRSFGKKL 382
++ IR+ V + F+GRPD + T+ + G+ L
Sbjct: 91 LDTIRQALVRQGDDFKGRPDLYTSTLITDGQSL 123
>M31667-1|AAA52163.1| 515|Homo sapiens CYP1A2 protein.
Length = 515
Score = 52.4 bits (120), Expect = 2e-06
Identities = 32/93 (34%), Positives = 56/93 (60%), Gaps = 2/93 (2%)
Frame = +2
Query: 110 RGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTG 289
+GL PP P P++G++L++ K HL SQ+YG++L +R+GS V+V++
Sbjct: 37 KGLKSPPEPWGWPLLGHVLTL------GKNPHLALSRMSQRYGDVLQIRIGSTPVLVLSR 90
Query: 290 IELIRE--VSNREVFEGRPDGFFYTMRSFGKKL 382
++ IR+ V + F+GRPD + T+ + G+ L
Sbjct: 91 LDTIRQALVRQGDDFKGRPDLYTSTLITDGQSL 123
>DQ022432-1|AAY26399.1| 516|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 2 protein.
Length = 516
Score = 52.4 bits (120), Expect = 2e-06
Identities = 32/93 (34%), Positives = 56/93 (60%), Gaps = 2/93 (2%)
Frame = +2
Query: 110 RGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTG 289
+GL PP P P++G++L++ K HL SQ+YG++L +R+GS V+V++
Sbjct: 37 KGLKSPPEPWGWPLLGHVLTL------GKNPHLALSRMSQRYGDVLQIRIGSTPVLVLSR 90
Query: 290 IELIRE--VSNREVFEGRPDGFFYTMRSFGKKL 382
++ IR+ V + F+GRPD + T+ + G+ L
Sbjct: 91 LDTIRQALVRQGDDFKGRPDLYTSTLITDGQSL 123
>BC067429-1|AAH67429.1| 516|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 2 protein.
Length = 516
Score = 52.4 bits (120), Expect = 2e-06
Identities = 32/93 (34%), Positives = 56/93 (60%), Gaps = 2/93 (2%)
Frame = +2
Query: 110 RGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTG 289
+GL PP P P++G++L++ K HL SQ+YG++L +R+GS V+V++
Sbjct: 37 KGLKSPPEPWGWPLLGHVLTL------GKNPHLALSRMSQRYGDVLQIRIGSTPVLVLSR 90
Query: 290 IELIRE--VSNREVFEGRPDGFFYTMRSFGKKL 382
++ IR+ V + F+GRPD + T+ + G+ L
Sbjct: 91 LDTIRQALVRQGDDFKGRPDLYTSTLITDGQSL 123
>BC067428-1|AAH67428.1| 516|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 2 protein.
Length = 516
Score = 52.4 bits (120), Expect = 2e-06
Identities = 32/93 (34%), Positives = 56/93 (60%), Gaps = 2/93 (2%)
Frame = +2
Query: 110 RGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTG 289
+GL PP P P++G++L++ K HL SQ+YG++L +R+GS V+V++
Sbjct: 37 KGLKSPPEPWGWPLLGHVLTL------GKNPHLALSRMSQRYGDVLQIRIGSTPVLVLSR 90
Query: 290 IELIRE--VSNREVFEGRPDGFFYTMRSFGKKL 382
++ IR+ V + F+GRPD + T+ + G+ L
Sbjct: 91 LDTIRQALVRQGDDFKGRPDLYTSTLITDGQSL 123
>BC067426-1|AAH67426.1| 516|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 2 protein.
Length = 516
Score = 52.4 bits (120), Expect = 2e-06
Identities = 32/93 (34%), Positives = 56/93 (60%), Gaps = 2/93 (2%)
Frame = +2
Query: 110 RGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTG 289
+GL PP P P++G++L++ K HL SQ+YG++L +R+GS V+V++
Sbjct: 37 KGLKSPPEPWGWPLLGHVLTL------GKNPHLALSRMSQRYGDVLQIRIGSTPVLVLSR 90
Query: 290 IELIRE--VSNREVFEGRPDGFFYTMRSFGKKL 382
++ IR+ V + F+GRPD + T+ + G+ L
Sbjct: 91 LDTIRQALVRQGDDFKGRPDLYTSTLITDGQSL 123
>BC067425-1|AAH67425.1| 516|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 2 protein.
Length = 516
Score = 52.4 bits (120), Expect = 2e-06
Identities = 32/93 (34%), Positives = 56/93 (60%), Gaps = 2/93 (2%)
Frame = +2
Query: 110 RGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTG 289
+GL PP P P++G++L++ K HL SQ+YG++L +R+GS V+V++
Sbjct: 37 KGLKSPPEPWGWPLLGHVLTL------GKNPHLALSRMSQRYGDVLQIRIGSTPVLVLSR 90
Query: 290 IELIRE--VSNREVFEGRPDGFFYTMRSFGKKL 382
++ IR+ V + F+GRPD + T+ + G+ L
Sbjct: 91 LDTIRQALVRQGDDFKGRPDLYTSTLITDGQSL 123
>BC067424-1|AAH67424.1| 516|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 2 protein.
Length = 516
Score = 52.4 bits (120), Expect = 2e-06
Identities = 32/93 (34%), Positives = 56/93 (60%), Gaps = 2/93 (2%)
Frame = +2
Query: 110 RGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTG 289
+GL PP P P++G++L++ K HL SQ+YG++L +R+GS V+V++
Sbjct: 37 KGLKSPPEPWGWPLLGHVLTL------GKNPHLALSRMSQRYGDVLQIRIGSTPVLVLSR 90
Query: 290 IELIRE--VSNREVFEGRPDGFFYTMRSFGKKL 382
++ IR+ V + F+GRPD + T+ + G+ L
Sbjct: 91 LDTIRQALVRQGDDFKGRPDLYTSTLITDGQSL 123
>AF253322-2|AAK25728.1| 516|Homo sapiens cytochrome P450 protein.
Length = 516
Score = 52.4 bits (120), Expect = 2e-06
Identities = 32/93 (34%), Positives = 56/93 (60%), Gaps = 2/93 (2%)
Frame = +2
Query: 110 RGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTG 289
+GL PP P P++G++L++ K HL SQ+YG++L +R+GS V+V++
Sbjct: 37 KGLKSPPEPWGWPLLGHVLTL------GKNPHLALSRMSQRYGDVLQIRIGSTPVLVLSR 90
Query: 290 IELIRE--VSNREVFEGRPDGFFYTMRSFGKKL 382
++ IR+ V + F+GRPD + T+ + G+ L
Sbjct: 91 LDTIRQALVRQGDDFKGRPDLYTSTLITDGQSL 123
>AF182274-1|AAF13599.1| 516|Homo sapiens cytochrome P450-1A2
protein.
Length = 516
Score = 52.4 bits (120), Expect = 2e-06
Identities = 32/93 (34%), Positives = 56/93 (60%), Gaps = 2/93 (2%)
Frame = +2
Query: 110 RGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTG 289
+GL PP P P++G++L++ K HL SQ+YG++L +R+GS V+V++
Sbjct: 37 KGLKSPPEPWGWPLLGHVLTL------GKNPHLALSRMSQRYGDVLQIRIGSTPVLVLSR 90
Query: 290 IELIRE--VSNREVFEGRPDGFFYTMRSFGKKL 382
++ IR+ V + F+GRPD + T+ + G+ L
Sbjct: 91 LDTIRQALVRQGDDFKGRPDLYTSTLITDGQSL 123
>X65962-1|CAA46778.1| 356|Homo sapiens cytochrome P-450 II C
protein.
Length = 356
Score = 51.6 bits (118), Expect = 3e-06
Identities = 41/153 (26%), Positives = 68/153 (44%), Gaps = 6/153 (3%)
Frame = +2
Query: 362 RSFGKKLGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKLC 541
RS ++ EE LV+ P + N++ +V KR+D +DQ L
Sbjct: 5 RSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLM 64
Query: 542 SLVMRLFKLVDMSG-GILNFLPFLRHFVPRLIGFTELQEIHNAL--HQYLREIIKEHQXN 712
F++++ + N P L P T + + N Y+RE +KEHQ +
Sbjct: 65 KRFNENFRILNSPWIQVCNNFPLLIDCFPG----THNKVLKNVALTRSYIREKVKEHQAS 120
Query: 713 LQLGAPKDVIDAFLIDM---LESQXDKLTLDDL 802
L + P+D ID FLI M ++Q + T+++L
Sbjct: 121 LDVNNPRDFIDCFLIKMEQEKDNQKSEFTIENL 153
>X13929-1|CAA32117.1| 448|Homo sapiens P-450 IIA3 protein (1 is 3rd
base in codon) protein.
Length = 448
Score = 51.6 bits (118), Expect = 3e-06
Identities = 37/146 (25%), Positives = 67/146 (45%), Gaps = 3/146 (2%)
Frame = +2
Query: 362 RSFGKKLGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKLC 541
R +++ EE L+ G I T+ N++ +V G R+D +D+ L
Sbjct: 97 RGIEERIQEEAGFLIDALRGTGGANIDPTFFLSRTVSNVISSIVFGDRFDYKDKEFLSLL 156
Query: 542 SLVMRLFKLVDMSGGILN--FLPFLRHFV-PRLIGFTELQEIHNALHQYLREIIKEHQXN 712
+++ +F+ S G L F ++H P+ F LQ L ++ + ++ +Q
Sbjct: 157 RMMLGIFQFTSTSTGQLYEMFSSVMKHLPGPQQQAFQLLQ----GLEDFIAKKVEHNQRT 212
Query: 713 LQLGAPKDVIDAFLIDMLESQXDKLT 790
L +P+D ID+FLI M E + + T
Sbjct: 213 LDPNSPRDFIDSFLIRMQEEEKNPNT 238
Score = 31.1 bits (67), Expect = 4.9
Identities = 22/72 (30%), Positives = 36/72 (50%), Gaps = 6/72 (8%)
Frame = +2
Query: 224 SQKYGNLLGLRLGSINVVVVTGIELIRE--VSNREVFEGRPD--GFFYTMRSFGKKL--G 385
S++YG + + LG VVV+ G + +RE V E F GR + F + + +G G
Sbjct: 16 SERYGPVFTIHLGPRRVVVLCGHDAVREALVDQAEEFSGRGEQATFDWVFKGYGVVFSNG 75
Query: 386 EECEALVQLRLA 421
E + L + +A
Sbjct: 76 ERAKQLRRFSIA 87
>BC033691-1|AAH33691.1| 504|Homo sapiens cytochrome P450, family 2,
subfamily S, polypeptide 1 protein.
Length = 504
Score = 51.6 bits (118), Expect = 3e-06
Identities = 70/255 (27%), Positives = 107/255 (41%), Gaps = 38/255 (14%)
Frame = +2
Query: 125 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSIN-VVVVTGIELI 301
PPGPTPLP++GNLL + R + + + S+KYG + + LG VVV+ G E +
Sbjct: 33 PPGPTPLPLLGNLLQL----RPGALYSGLMR-LSKKYGPVFTIYLGPWRPVVVLVGQEAV 87
Query: 302 REV--SNREVFEGRP---------DG---FF-----------YTMRS-----FGKKLGE- 388
RE E F GR DG FF +TM + GK+ GE
Sbjct: 88 REALGGQAEEFSGRGTVAMLEGTFDGHGVFFSNGERWRQLRKFTMLALRDLGMGKREGEE 147
Query: 389 ----ECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKLCSLVMR 556
E LV+ G P + + N++ L+ G R+ ED+ + +
Sbjct: 148 LIQAEARCLVETFQGTEGRPFDPSLLLAQATSNVVCSLLFGLRFSYEDKEFQAVVRAAGG 207
Query: 557 LFKLVDMSGGILNFLPFLRHFVPRLIG-FTELQEIHNALHQYLREIIKEHQXNLQLGAP- 730
V GG F+ L G +L + L + +++HQ NL P
Sbjct: 208 TLLGVSSQGG--QTYEMFSWFLRPLPGPHKQLLHHVSTLAAFTVRQVQQHQGNLDASGPA 265
Query: 731 KDVIDAFLIDMLESQ 775
+D++DAFL+ M + +
Sbjct: 266 RDLVDAFLLKMAQEE 280
>AY358603-1|AAQ88966.1| 504|Homo sapiens Cytochrome p450 protein.
Length = 504
Score = 51.6 bits (118), Expect = 3e-06
Identities = 70/255 (27%), Positives = 107/255 (41%), Gaps = 38/255 (14%)
Frame = +2
Query: 125 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSIN-VVVVTGIELI 301
PPGPTPLP++GNLL + R + + + S+KYG + + LG VVV+ G E +
Sbjct: 33 PPGPTPLPLLGNLLQL----RPGALYSGLMR-LSKKYGPVFTIYLGPWRPVVVLVGQEAV 87
Query: 302 REV--SNREVFEGRP---------DG---FF-----------YTMRS-----FGKKLGE- 388
RE E F GR DG FF +TM + GK+ GE
Sbjct: 88 REALGGQAEEFSGRGTVAMLEGTFDGHGVFFSNGERWRQLRKFTMLALRDLGMGKREGEE 147
Query: 389 ----ECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKLCSLVMR 556
E LV+ G P + + N++ L+ G R+ ED+ + +
Sbjct: 148 LIQAEARCLVETFQGTEGRPFDPSLLLAQATSNVVCSLLFGLRFSYEDKEFQAVVRAAGG 207
Query: 557 LFKLVDMSGGILNFLPFLRHFVPRLIG-FTELQEIHNALHQYLREIIKEHQXNLQLGAP- 730
V GG F+ L G +L + L + +++HQ NL P
Sbjct: 208 TLLGVSSQGG--QTYEMFSWFLRPLPGPHKQLLHHVSTLAAFTVRQVQQHQGNLDASGPA 265
Query: 731 KDVIDAFLIDMLESQ 775
+D++DAFL+ M + +
Sbjct: 266 RDLVDAFLLKMAQEE 280
>AK027605-1|BAB55227.1| 564|Homo sapiens protein ( Homo sapiens
cDNA FLJ14699 fis, clone NT2RP2006571, moderately
similar to CYTOCHROME P450 2G1 (EC 1.14.14.1). ).
Length = 564
Score = 51.6 bits (118), Expect = 3e-06
Identities = 70/255 (27%), Positives = 107/255 (41%), Gaps = 38/255 (14%)
Frame = +2
Query: 125 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSIN-VVVVTGIELI 301
PPGPTPLP++GNLL + R + + + S+KYG + + LG VVV+ G E +
Sbjct: 33 PPGPTPLPLLGNLLQL----RPGALYSGLMR-LSKKYGPVFTIYLGPWRPVVVLVGQEAV 87
Query: 302 REV--SNREVFEGRP---------DG---FF-----------YTMRS-----FGKKLGE- 388
RE E F GR DG FF +TM + GK+ GE
Sbjct: 88 REALGGQAEEFSGRGTVAMLEGTFDGHGVFFSNGERWRQLRKFTMLALRDLGMGKREGEE 147
Query: 389 ----ECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKLCSLVMR 556
E LV+ G P + + N++ L+ G R+ ED+ + +
Sbjct: 148 LIQAEARCLVETFQGTEGRPFDPSLLLAQATSNVVCSLLFGLRFSYEDKEFQAVVRAAGG 207
Query: 557 LFKLVDMSGGILNFLPFLRHFVPRLIG-FTELQEIHNALHQYLREIIKEHQXNLQLGAP- 730
V GG F+ L G +L + L + +++HQ NL P
Sbjct: 208 TLLGVSSQGG--QTYEMFSWFLRPLPGPHKQLLHHVSTLAAFTVRQVQQHQGNLDASGPA 265
Query: 731 KDVIDAFLIDMLESQ 775
+D++DAFL+ M + +
Sbjct: 266 RDLVDAFLLKMAQEE 280
>AF335278-1|AAK13498.1| 504|Homo sapiens cytochrome P450 2S1
protein.
Length = 504
Score = 51.6 bits (118), Expect = 3e-06
Identities = 70/255 (27%), Positives = 107/255 (41%), Gaps = 38/255 (14%)
Frame = +2
Query: 125 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSIN-VVVVTGIELI 301
PPGPTPLP++GNLL + R + + + S+KYG + + LG VVV+ G E +
Sbjct: 33 PPGPTPLPLLGNLLQL----RPGALYSGLMR-LSKKYGPVFTIYLGPWRPVVVLVGQEAV 87
Query: 302 REV--SNREVFEGRP---------DG---FF-----------YTMRS-----FGKKLGE- 388
RE E F GR DG FF +TM + GK+ GE
Sbjct: 88 REALGGQAEEFSGRGTVAMLEGTFDGHGVFFSNGERWRQLRKFTMLALRDLGMGKREGEE 147
Query: 389 ----ECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKLCSLVMR 556
E LV+ G P + + N++ L+ G R+ ED+ + +
Sbjct: 148 LIQAEARCLVETFQGTEGRPFDPSLLLAQATSNVVCSLLFGLRFSYEDKEFQAVVRAAGG 207
Query: 557 LFKLVDMSGGILNFLPFLRHFVPRLIG-FTELQEIHNALHQYLREIIKEHQXNLQLGAP- 730
V GG F+ L G +L + L + +++HQ NL P
Sbjct: 208 TLLGVSSQGG--QTYEMFSWFLRPLPGPHKQLLHHVSTLAAFTVRQVQQHQGNLDASGPA 265
Query: 731 KDVIDAFLIDMLESQ 775
+D++DAFL+ M + +
Sbjct: 266 RDLVDAFLLKMAQEE 280
>M21941-1|AAA52160.1| 480|Homo sapiens CYP2C protein.
Length = 480
Score = 50.8 bits (116), Expect = 6e-06
Identities = 40/143 (27%), Positives = 63/143 (44%), Gaps = 3/143 (2%)
Frame = +2
Query: 362 RSFGKKLGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKLC 541
RS ++ EE LV+ P + N++ +V KR+D +DQ+ L
Sbjct: 129 RSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQKFLTLM 188
Query: 542 SLVMRLFKLVDMSG-GILNFLPFLRHFVPRLIGFTELQEIHNAL--HQYLREIIKEHQXN 712
F++++ + N P L P T + + N Y+RE +KEHQ +
Sbjct: 189 KRFNENFRILNSPWIQVCNNFPLLIDCFPG----THNKVLKNVALTRSYIREKVKEHQAS 244
Query: 713 LQLGAPKDVIDAFLIDMLESQXD 781
L + P+D ID FLI M E + D
Sbjct: 245 LDVNNPRDFIDCFLIKM-EQEKD 266
Score = 47.6 bits (108), Expect = 5e-05
Identities = 28/73 (38%), Positives = 41/73 (56%), Gaps = 2/73 (2%)
Frame = +2
Query: 125 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIR 304
PPGPTPLPI+GN+L + K C + ++S+ YG + + G +VV G E ++
Sbjct: 20 PPGPTPLPIIGNMLQI---DVKDICKS--FTNFSKVYGPVFTVYFGMNPIVVFHGYEAVK 74
Query: 305 E--VSNREVFEGR 337
E + N E F GR
Sbjct: 75 EALIDNGEEFSGR 87
>Y00498-1|CAA68550.1| 490|Homo sapiens IIC2 protein.
Length = 490
Score = 50.0 bits (114), Expect = 1e-05
Identities = 40/143 (27%), Positives = 62/143 (43%), Gaps = 3/143 (2%)
Frame = +2
Query: 362 RSFGKKLGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKLC 541
RS ++ EE LV+ P + N++ +V KR+D +DQ L
Sbjct: 139 RSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLM 198
Query: 542 SLVMRLFKLVDMSG-GILNFLPFLRHFVPRLIGFTELQEIHNAL--HQYLREIIKEHQXN 712
F++++ + N P L P T + + N Y+RE +KEHQ +
Sbjct: 199 KRFNENFRILNSPWIQVCNNFPLLIDCFPG----THNKVLKNVALTRSYIREKVKEHQAS 254
Query: 713 LQLGAPKDVIDAFLIDMLESQXD 781
L + P+D ID FLI M E + D
Sbjct: 255 LDVNNPRDFIDCFLIKM-EQEKD 276
Score = 47.6 bits (108), Expect = 5e-05
Identities = 28/73 (38%), Positives = 41/73 (56%), Gaps = 2/73 (2%)
Frame = +2
Query: 125 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIR 304
PPGPTPLPI+GN+L + K C + ++S+ YG + + G +VV G E ++
Sbjct: 30 PPGPTPLPIIGNMLQI---DVKDICKS--FTNFSKVYGPVFTVYFGMNPIVVFHGYEAVK 84
Query: 305 E--VSNREVFEGR 337
E + N E F GR
Sbjct: 85 EALIDNGEEFSGR 97
>L00389-1|AAA35738.1| 516|Homo sapiens protein ( Human cytochrome
P-450 4 gene, exon 7, and three Alu repeats in the 3'
flank. ).
Length = 516
Score = 50.0 bits (114), Expect = 1e-05
Identities = 31/93 (33%), Positives = 55/93 (59%), Gaps = 2/93 (2%)
Frame = +2
Query: 110 RGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTG 289
+GL PP P P++G++L++ K HL SQ+YG++L + +GS V+V++
Sbjct: 37 KGLKSPPEPWGWPLLGHVLTL------GKNPHLALSRMSQRYGDVLQISIGSTPVLVLSR 90
Query: 290 IELIRE--VSNREVFEGRPDGFFYTMRSFGKKL 382
++ IR+ V + F+GRPD + T+ + G+ L
Sbjct: 91 LDTIRQALVRQGDDFKGRPDLYTSTLITDGQSL 123
>BC020596-1|AAH20596.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 8 protein.
Length = 490
Score = 50.0 bits (114), Expect = 1e-05
Identities = 40/143 (27%), Positives = 62/143 (43%), Gaps = 3/143 (2%)
Frame = +2
Query: 362 RSFGKKLGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKLC 541
RS ++ EE LV+ P + N++ +V KR+D +DQ L
Sbjct: 139 RSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLM 198
Query: 542 SLVMRLFKLVDMSG-GILNFLPFLRHFVPRLIGFTELQEIHNAL--HQYLREIIKEHQXN 712
F++++ + N P L P T + + N Y+RE +KEHQ +
Sbjct: 199 KRFNENFRILNSPWIQVCNNFPLLIDCFPG----THNKVLKNVALTRSYIREKVKEHQAS 254
Query: 713 LQLGAPKDVIDAFLIDMLESQXD 781
L + P+D ID FLI M E + D
Sbjct: 255 LDVNNPRDFIDCFLIKM-EQEKD 276
Score = 47.2 bits (107), Expect = 7e-05
Identities = 28/73 (38%), Positives = 41/73 (56%), Gaps = 2/73 (2%)
Frame = +2
Query: 125 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIR 304
PPGPTPLPI+GN+L + K C + ++S+ YG + + G +VV G E ++
Sbjct: 30 PPGPTPLPIIGNMLQI---DVKDICKS--FTNFSKVYGPVFTVYFGMNPIVVFHGYESVK 84
Query: 305 E--VSNREVFEGR 337
E + N E F GR
Sbjct: 85 EALIDNGEEFSGR 97
>AY514490-1|AAR89907.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 8 protein.
Length = 490
Score = 50.0 bits (114), Expect = 1e-05
Identities = 40/143 (27%), Positives = 62/143 (43%), Gaps = 3/143 (2%)
Frame = +2
Query: 362 RSFGKKLGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKLC 541
RS ++ EE LV+ P + N++ +V KR+D +DQ L
Sbjct: 139 RSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLM 198
Query: 542 SLVMRLFKLVDMSG-GILNFLPFLRHFVPRLIGFTELQEIHNAL--HQYLREIIKEHQXN 712
F++++ + N P L P T + + N Y+RE +KEHQ +
Sbjct: 199 KRFNENFRILNSPWIQVCNNFPLLIDCFPG----THNKVLKNVALTRSYIREKVKEHQAS 254
Query: 713 LQLGAPKDVIDAFLIDMLESQXD 781
L + P+D ID FLI M E + D
Sbjct: 255 LDVNNPRDFIDCFLIKM-EQEKD 276
Score = 47.6 bits (108), Expect = 5e-05
Identities = 28/73 (38%), Positives = 41/73 (56%), Gaps = 2/73 (2%)
Frame = +2
Query: 125 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIR 304
PPGPTPLPI+GN+L + K C + ++S+ YG + + G +VV G E ++
Sbjct: 30 PPGPTPLPIIGNMLQI---DVKDICKS--FTNFSKVYGPVFTVYFGMNPIVVFHGYEAVK 84
Query: 305 E--VSNREVFEGR 337
E + N E F GR
Sbjct: 85 EALIDNGEEFSGR 97
>AL359672-5|CAH71307.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 8 protein.
Length = 490
Score = 50.0 bits (114), Expect = 1e-05
Identities = 40/143 (27%), Positives = 62/143 (43%), Gaps = 3/143 (2%)
Frame = +2
Query: 362 RSFGKKLGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKLC 541
RS ++ EE LV+ P + N++ +V KR+D +DQ L
Sbjct: 139 RSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLM 198
Query: 542 SLVMRLFKLVDMSG-GILNFLPFLRHFVPRLIGFTELQEIHNAL--HQYLREIIKEHQXN 712
F++++ + N P L P T + + N Y+RE +KEHQ +
Sbjct: 199 KRFNENFRILNSPWIQVCNNFPLLIDCFPG----THNKVLKNVALTRSYIREKVKEHQAS 254
Query: 713 LQLGAPKDVIDAFLIDMLESQXD 781
L + P+D ID FLI M E + D
Sbjct: 255 LDVNNPRDFIDCFLIKM-EQEKD 276
Score = 47.6 bits (108), Expect = 5e-05
Identities = 28/73 (38%), Positives = 41/73 (56%), Gaps = 2/73 (2%)
Frame = +2
Query: 125 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIR 304
PPGPTPLPI+GN+L + K C + ++S+ YG + + G +VV G E ++
Sbjct: 30 PPGPTPLPIIGNMLQI---DVKDICKS--FTNFSKVYGPVFTVYFGMNPIVVFHGYEAVK 84
Query: 305 E--VSNREVFEGR 337
E + N E F GR
Sbjct: 85 EALIDNGEEFSGR 97
>BC067427-1|AAH67427.1| 516|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 2 protein.
Length = 516
Score = 49.6 bits (113), Expect = 1e-05
Identities = 31/93 (33%), Positives = 55/93 (59%), Gaps = 2/93 (2%)
Frame = +2
Query: 110 RGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTG 289
+GL PP P P++G++L++ K HL SQ+YG++L +R+ S V+V++
Sbjct: 37 KGLKSPPEPWGWPLLGHVLTL------GKNPHLALSRMSQRYGDVLQIRIDSTPVLVLSR 90
Query: 290 IELIRE--VSNREVFEGRPDGFFYTMRSFGKKL 382
++ IR+ V + F+GRPD + T+ + G+ L
Sbjct: 91 LDTIRQALVRQGDDFKGRPDLYTSTLITDGQSL 123
>M17398-1|AAA35740.1| 393|Homo sapiens protein ( Human cytochrome
P-450 1 mRNA, complete cds, clone Hp1-2. ).
Length = 393
Score = 48.8 bits (111), Expect = 2e-05
Identities = 39/143 (27%), Positives = 62/143 (43%), Gaps = 3/143 (2%)
Frame = +2
Query: 362 RSFGKKLGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKLC 541
RS ++ EE LV+ P + N++ +V KR+D +DQ L
Sbjct: 139 RSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLM 198
Query: 542 SLVMRLFKLVDMSG-GILNFLPFLRHFVPRLIGFTELQEIHNAL--HQYLREIIKEHQXN 712
F++++ + N P L P T + + N Y+RE +KEHQ +
Sbjct: 199 KRFNENFRILNSPWIQVCNNFPLLIDCFPG----THNKVLKNVALTRSYIREKVKEHQAS 254
Query: 713 LQLGAPKDVIDAFLIDMLESQXD 781
L + P+D +D FLI M E + D
Sbjct: 255 LDVNNPRDFMDCFLIKM-EQEKD 276
Score = 47.6 bits (108), Expect = 5e-05
Identities = 28/73 (38%), Positives = 41/73 (56%), Gaps = 2/73 (2%)
Frame = +2
Query: 125 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIR 304
PPGPTPLPI+GN+L + K C + ++S+ YG + + G +VV G E ++
Sbjct: 30 PPGPTPLPIIGNMLQI---DVKDICKS--FTNFSKVYGPVFTVYFGMNPIVVFHGYEAVK 84
Query: 305 E--VSNREVFEGR 337
E + N E F GR
Sbjct: 85 EALIDNGEEFSGR 97
>M17397-1|AAA35739.1| 490|Homo sapiens protein ( Human cytochrome
P-450 1 functional form mRNA, complete cds. ).
Length = 490
Score = 48.8 bits (111), Expect = 2e-05
Identities = 39/143 (27%), Positives = 62/143 (43%), Gaps = 3/143 (2%)
Frame = +2
Query: 362 RSFGKKLGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKLC 541
RS ++ EE LV+ P + N++ +V KR+D +DQ L
Sbjct: 139 RSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLM 198
Query: 542 SLVMRLFKLVDMSG-GILNFLPFLRHFVPRLIGFTELQEIHNAL--HQYLREIIKEHQXN 712
F++++ + N P L P T + + N Y+RE +KEHQ +
Sbjct: 199 KRFNENFRILNSPWIQVCNNFPLLIDCFPG----THNKVLKNVALTRSYIREKVKEHQAS 254
Query: 713 LQLGAPKDVIDAFLIDMLESQXD 781
L + P+D +D FLI M E + D
Sbjct: 255 LDVNNPRDFMDCFLIKM-EQEKD 276
Score = 47.6 bits (108), Expect = 5e-05
Identities = 28/73 (38%), Positives = 41/73 (56%), Gaps = 2/73 (2%)
Frame = +2
Query: 125 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIR 304
PPGPTPLPI+GN+L + K C + ++S+ YG + + G +VV G E ++
Sbjct: 30 PPGPTPLPIIGNMLQI---DVKDICKS--FTNFSKVYGPVFTVYFGMNPIVVFHGYEAVK 84
Query: 305 E--VSNREVFEGR 337
E + N E F GR
Sbjct: 85 EALIDNGEEFSGR 97
>M61858-1|AAA52145.1| 370|Homo sapiens CYP2C17 protein.
Length = 370
Score = 48.0 bits (109), Expect = 4e-05
Identities = 42/152 (27%), Positives = 70/152 (46%), Gaps = 5/152 (3%)
Frame = +2
Query: 362 RSFGKKLGEECEALVQ-LRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKL 538
RS ++ EE LV+ LR +A P + N++ ++ KR+D +DQ+ L
Sbjct: 19 RSIEDRVQEEARCLVEELRKTNAS-PCDPTFILGCAPCNVICSIIFHKRFDYKDQQFLNL 77
Query: 539 CSLVMRLFKLVDMSG-GILNFLPFLRHFVPRLIGFTELQEIHNALHQYLREIIKEHQXNL 715
+ ++V I N + + P +L + L Y+ E IKEHQ +L
Sbjct: 78 MEKLNENIRIVSTPWIQICNNFSTIIDYFPG--SHNKLLKNLLTLKSYVLERIKEHQESL 135
Query: 716 QLGAPKDVIDAFLIDMLE---SQXDKLTLDDL 802
+ P+D ID FLI M + +Q + T++ L
Sbjct: 136 DMNNPRDFIDCFLIKMEQEKHNQQSEFTVESL 167
>M24499-1|AAA36403.1| 373|Homo sapiens cytochrome P450db1 protein.
Length = 373
Score = 48.0 bits (109), Expect = 4e-05
Identities = 37/138 (26%), Positives = 63/138 (45%), Gaps = 4/138 (2%)
Frame = +2
Query: 362 RSFGKKLGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKLC 541
+S + + EE L +G P N + + N++ L G+R++ +D R +L
Sbjct: 23 KSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLL 82
Query: 542 SLVMRLFKLVDMSG---GILNFLPFLRHFVPRLIGFTELQEIHNALHQYLREIIKEHQXN 712
L K + SG +LN +P L H +P L G ++ A L E++ EH+
Sbjct: 83 DLAQEGLK--EESGFLREVLNAVPVLLH-IPALAG--KVLRFQKAFLTQLDELLTEHRMT 137
Query: 713 LQ-LGAPKDVIDAFLIDM 763
P+D+ +AFL +M
Sbjct: 138 WDPAQPPRDLTEAFLAEM 155
>M21942-1|AAA52161.1| 462|Homo sapiens CYP2C protein.
Length = 462
Score = 48.0 bits (109), Expect = 4e-05
Identities = 39/143 (27%), Positives = 61/143 (42%), Gaps = 3/143 (2%)
Frame = +2
Query: 362 RSFGKKLGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKLC 541
RS ++ EE LV P + N++ +V KR+D +DQ L
Sbjct: 111 RSIEDRVQEEAHCLVDELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLM 170
Query: 542 SLVMRLFKLVDMSG-GILNFLPFLRHFVPRLIGFTELQEIHNAL--HQYLREIIKEHQXN 712
F++++ + N P L P T + + N Y+RE ++EHQ +
Sbjct: 171 KRFNENFRILNSPWIQVCNNFPLLIDCFPG----THNKVLKNVALTRSYIREKVREHQAS 226
Query: 713 LQLGAPKDVIDAFLIDMLESQXD 781
L + P+D ID FLI M E + D
Sbjct: 227 LDVNNPRDFIDCFLIKM-EQEKD 248
Score = 47.6 bits (108), Expect = 5e-05
Identities = 28/73 (38%), Positives = 41/73 (56%), Gaps = 2/73 (2%)
Frame = +2
Query: 125 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIR 304
PPGPTPLPI+GN+L + K C + ++S+ YG + + G +VV G E ++
Sbjct: 2 PPGPTPLPIIGNMLQI---DVKDICKS--FTNFSKVYGPVFTVYFGMNPIVVFHGYEAVK 56
Query: 305 E--VSNREVFEGR 337
E + N E F GR
Sbjct: 57 EALIDNGEEFSGR 69
>M21940-1|AAA52159.1| 383|Homo sapiens CYP2C protein.
Length = 383
Score = 46.8 bits (106), Expect = 9e-05
Identities = 36/153 (23%), Positives = 68/153 (44%), Gaps = 5/153 (3%)
Frame = +2
Query: 362 RSFGKKLGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKLC 541
RS ++ EE LV+ P + N++ ++ KR+D +DQ+ L
Sbjct: 32 RSIEDRVQEEARCLVEELRKTKASPCDPTFILGCAPCNVICSIIFHKRFDYKDQQFLNLM 91
Query: 542 SLVMRLFKLVDMSGGIL--NFLPFLRHFVPRLIGFTELQEIHNALHQYLREIIKEHQXNL 715
+ K++ + NF P + +F +L + + Y+ E +KEHQ ++
Sbjct: 92 EKLNENIKILSSPWIQICNNFSPIIDYFPGT---HNKLLKNVAFMKSYILEKVKEHQESM 148
Query: 716 QLGAPKDVIDAFLIDM---LESQXDKLTLDDLQ 805
+ P+D ID FL+ M +Q + T++ L+
Sbjct: 149 DMNNPQDFIDCFLMKMEKEKHNQPSEFTIESLE 181
>L07093-1|AAA36660.1| 468|Homo sapiens cytochrome P450 protein.
Length = 468
Score = 46.4 bits (105), Expect = 1e-04
Identities = 36/151 (23%), Positives = 67/151 (44%), Gaps = 4/151 (2%)
Frame = +2
Query: 362 RSFGKKLGEECEALVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKLC 541
RS ++ EE LV+ P + N++ ++ KR+D +DQ+ L
Sbjct: 117 RSIEDRVQEEARCLVEELRKTKASPCDPTFILGCAPCNVICSIIFQKRFDYKDQQFLNLM 176
Query: 542 SLVMRLFKLVDMSG-GILNFLPFLRHFVPRLIGFTELQEIHNALHQYLREIIKEHQXNLQ 718
+ ++V I N P + + P +L + + + E +KEHQ ++
Sbjct: 177 EKLNENIRIVSTPWIQICNNFPTIIDYFPGT--HNKLLKNLAFMESDILEKVKEHQESMD 234
Query: 719 LGAPKDVIDAFLIDM---LESQXDKLTLDDL 802
+ P+D ID FLI M ++Q + T+++L
Sbjct: 235 INNPRDFIDCFLIKMEKEKQNQQSEFTIENL 265
>DQ282155-1|ABB77903.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 46.4 bits (105), Expect = 1e-04
Identities = 33/117 (28%), Positives = 56/117 (47%), Gaps = 4/117 (3%)
Frame = +2
Query: 425 AGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKLCSLVMRLFKLVDMSG---GILN 595
+G P N + + N++ L G+R++ +D R +L L K + SG +LN
Sbjct: 168 SGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLK--EESGFLREVLN 225
Query: 596 FLPFLRHFVPRLIGFTELQEIHNALHQYLREIIKEHQXNLQ-LGAPKDVIDAFLIDM 763
+P L H +P L G ++ A L E++ EH+ P+D+ +AFL +M
Sbjct: 226 AVPVLLH-IPALAG--KVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEM 279
Score = 45.6 bits (103), Expect = 2e-04
Identities = 32/96 (33%), Positives = 51/96 (53%), Gaps = 3/96 (3%)
Frame = +2
Query: 101 RRHRGLC-YPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVV 277
RR R YPPGP PLP +GNLL V +++ + C + +++G++ L+L VV
Sbjct: 25 RRQRWAARYPPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWTPVV 79
Query: 278 VVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKK 379
V+ G+ +RE V++ E RP + FG +
Sbjct: 80 VLNGLAAVREALVTHGEDTADRPPVPITQILGFGPR 115
>DQ282162-1|ABB77909.1| 500|Homo sapiens cytochrome P450 2D6
protein.
Length = 500
Score = 46.0 bits (104), Expect = 2e-04
Identities = 32/96 (33%), Positives = 51/96 (53%), Gaps = 3/96 (3%)
Frame = +2
Query: 101 RRHRGLC-YPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVV 277
RR R YPPGP PLP +GNLL V +++ + C + +++G++ L+L VV
Sbjct: 25 RRQRWAARYPPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWTPVV 79
Query: 278 VVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKK 379
V+ G+ +RE V++ E RP + FG +
Sbjct: 80 VLNGLAAVREALVTHGEDTADRPPVPIIQILGFGPR 115
>AY513607-1|AAR90938.1| 100|Homo sapiens truncated cytochrome P450
2A13 variant 4 protein.
Length = 100
Score = 45.2 bits (102), Expect = 3e-04
Identities = 29/80 (36%), Positives = 41/80 (51%), Gaps = 2/80 (2%)
Frame = +2
Query: 101 RRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 280
R+ RG PPGPTPLP +GN L + E + S++YG + + LG VVV
Sbjct: 27 RKSRGKL-PPGPTPLPFIGNYLQLNTEQMYNSLMKI-----SERYGPVFTIHLGPRRVVV 80
Query: 281 VTGIELIRE--VSNREVFEG 334
+ G + ++E V E F G
Sbjct: 81 LCGHDAVKEALVDQAEEFSG 100
>BC025761-1|AAH25761.2| 490|Homo sapiens cytochrome P450, family 2,
subfamily W, polypeptide 1 protein.
Length = 490
Score = 43.6 bits (98), Expect = 9e-04
Identities = 23/62 (37%), Positives = 34/62 (54%)
Frame = +2
Query: 122 YPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELI 301
+PPGP PLP+VGNL + + L S++YG + + LG VV+TG E +
Sbjct: 31 WPPGPRPLPLVGNLHLLRLSQQDRSLMEL-----SERYGPVFTVHLGRQKTVVLTGFEAV 85
Query: 302 RE 307
+E
Sbjct: 86 KE 87
>U56438-1|AAC50809.1| 543|Homo sapiens dioxin-inducible cytochrome
P450 protein.
Length = 543
Score = 43.2 bits (97), Expect = 0.001
Identities = 24/101 (23%), Positives = 55/101 (54%), Gaps = 2/101 (1%)
Frame = +2
Query: 461 ITIVNILWRLVAGKRYDLEDQRLKKLCSLVMRLFKLVDMSGGILNFLPFLRHFV-PRLIG 637
+ + N++ + G RY +D ++L S + V +G +++ +P+L++F P
Sbjct: 199 VAVANVMSAVCFGCRYSHDDPEFRELLSHNEEFGRTVG-AGSLVDVMPWLQYFPNPVRTV 257
Query: 638 FTELQEIHNALHQYLREIIKEHQXNLQLGA-PKDVIDAFLI 757
F E ++++ ++ + H +L+ GA P+D++DAF++
Sbjct: 258 FREFEQLNRNFSNFILDKFLRHCESLRPGAAPRDMMDAFIL 298
Score = 42.3 bits (95), Expect = 0.002
Identities = 28/96 (29%), Positives = 47/96 (48%), Gaps = 2/96 (2%)
Frame = +2
Query: 101 RRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 280
RR + PPGP P++GN +V + HL + +++YG++ +RLGS +VV
Sbjct: 43 RRRQLRSAPPGPFAWPLIGNAAAV------GQAAHLSFARLARRYGDVFQIRLGSCPIVV 96
Query: 281 VTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKKL 382
+ G I + V F RP + + S G+ +
Sbjct: 97 LNGERAIHQALVQQGSAFADRPAFASFRVVSGGRSM 132
>U03688-1|AAA19567.1| 543|Homo sapiens cytochrome P450 protein.
Length = 543
Score = 43.2 bits (97), Expect = 0.001
Identities = 24/101 (23%), Positives = 55/101 (54%), Gaps = 2/101 (1%)
Frame = +2
Query: 461 ITIVNILWRLVAGKRYDLEDQRLKKLCSLVMRLFKLVDMSGGILNFLPFLRHFV-PRLIG 637
+ + N++ + G RY +D ++L S + V +G +++ +P+L++F P
Sbjct: 199 VAVANVMSAVCFGCRYSHDDPEFRELLSHNEEFGRTVG-AGSLVDVMPWLQYFPNPVRTV 257
Query: 638 FTELQEIHNALHQYLREIIKEHQXNLQLGA-PKDVIDAFLI 757
F E ++++ ++ + H +L+ GA P+D++DAF++
Sbjct: 258 FREFEQLNRNFSNFILDKFLRHCESLRPGAAPRDMMDAFIL 298
Score = 42.3 bits (95), Expect = 0.002
Identities = 28/96 (29%), Positives = 47/96 (48%), Gaps = 2/96 (2%)
Frame = +2
Query: 101 RRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 280
RR + PPGP P++GN +V + HL + +++YG++ +RLGS +VV
Sbjct: 43 RRRQLRSAPPGPFAWPLIGNAAAV------GQAAHLSFARLARRYGDVFQIRLGSCPIVV 96
Query: 281 VTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKKL 382
+ G I + V F RP + + S G+ +
Sbjct: 97 LNGERAIHQALVQQGSAFADRPAFASFRVVSGGRSM 132
>L39098-1|AAL31347.1| 160|Homo sapiens S-mephenytoin 4-hydroxylase
protein.
Length = 160
Score = 43.2 bits (97), Expect = 0.001
Identities = 26/73 (35%), Positives = 40/73 (54%), Gaps = 2/73 (2%)
Frame = +2
Query: 125 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIR 304
PPGPTPLP++GN+L + + +L S+ YG + L G +VV+ G E+++
Sbjct: 30 PPGPTPLPVIGNILQIDIKDVSKSLTNL-----SKIYGPVFTLYFGLERMVVLHGYEVVK 84
Query: 305 E--VSNREVFEGR 337
E + E F GR
Sbjct: 85 EALIDLGEEFSGR 97
>BT019979-1|AAV38782.1| 543|Homo sapiens cytochrome P450, family 1,
subfamily B, polypeptide 1 protein.
Length = 543
Score = 43.2 bits (97), Expect = 0.001
Identities = 24/101 (23%), Positives = 55/101 (54%), Gaps = 2/101 (1%)
Frame = +2
Query: 461 ITIVNILWRLVAGKRYDLEDQRLKKLCSLVMRLFKLVDMSGGILNFLPFLRHFV-PRLIG 637
+ + N++ + G RY +D ++L S + V +G +++ +P+L++F P
Sbjct: 199 VAVANVMSAVCFGCRYSHDDPEFRELLSHNEEFGRTVG-AGSLVDVMPWLQYFPNPVRTV 257
Query: 638 FTELQEIHNALHQYLREIIKEHQXNLQLGA-PKDVIDAFLI 757
F E ++++ ++ + H +L+ GA P+D++DAF++
Sbjct: 258 FREFEQLNRNFSNFILDKFLRHCESLRPGAAPRDMMDAFIL 298
Score = 42.3 bits (95), Expect = 0.002
Identities = 28/96 (29%), Positives = 47/96 (48%), Gaps = 2/96 (2%)
Frame = +2
Query: 101 RRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 280
RR + PPGP P++GN +V + HL + +++YG++ +RLGS +VV
Sbjct: 43 RRRQLRSAPPGPFAWPLIGNAAAV------GQAAHLSFARLARRYGDVFQIRLGSCPIVV 96
Query: 281 VTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKKL 382
+ G I + V F RP + + S G+ +
Sbjct: 97 LNGERAIHQALVQQGSAFADRPAFASFRVVSGGRSM 132
>BC109084-1|AAI09085.1| 448|Homo sapiens CYP24A1 protein protein.
Length = 448
Score = 43.2 bits (97), Expect = 0.001
Identities = 19/50 (38%), Positives = 31/50 (62%)
Frame = +2
Query: 128 PGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVV 277
PGPT P++G+LL +LW+ K H + + + +KYG + ++LGS V
Sbjct: 59 PGPTSWPLLGSLLQILWKGGLKKQHDTLVE-YHKKYGKIFRMKLGSFESV 107
>BC109083-1|AAI09084.1| 448|Homo sapiens CYP24A1 protein protein.
Length = 448
Score = 43.2 bits (97), Expect = 0.001
Identities = 19/50 (38%), Positives = 31/50 (62%)
Frame = +2
Query: 128 PGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVV 277
PGPT P++G+LL +LW+ K H + + + +KYG + ++LGS V
Sbjct: 59 PGPTSWPLLGSLLQILWKGGLKKQHDTLVE-YHKKYGKIFRMKLGSFESV 107
>BC012049-1|AAH12049.1| 543|Homo sapiens cytochrome P450, family 1,
subfamily B, polypeptide 1 protein.
Length = 543
Score = 43.2 bits (97), Expect = 0.001
Identities = 24/101 (23%), Positives = 55/101 (54%), Gaps = 2/101 (1%)
Frame = +2
Query: 461 ITIVNILWRLVAGKRYDLEDQRLKKLCSLVMRLFKLVDMSGGILNFLPFLRHFV-PRLIG 637
+ + N++ + G RY +D ++L S + V +G +++ +P+L++F P
Sbjct: 199 VAVANVMSAVCFGCRYSHDDPEFRELLSHNEEFGRTVG-AGSLVDVMPWLQYFPNPVRTV 257
Query: 638 FTELQEIHNALHQYLREIIKEHQXNLQLGA-PKDVIDAFLI 757
F E ++++ ++ + H +L+ GA P+D++DAF++
Sbjct: 258 FREFEQLNRNFSNFILDKFLRHCESLRPGAAPRDMMDAFIL 298
Score = 42.3 bits (95), Expect = 0.002
Identities = 28/96 (29%), Positives = 47/96 (48%), Gaps = 2/96 (2%)
Frame = +2
Query: 101 RRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 280
RR + PPGP P++GN +V + HL + +++YG++ +RLGS +VV
Sbjct: 43 RRRQLRSAPPGPFAWPLIGNAAAV------GQAAHLSFARLARRYGDVFQIRLGSCPIVV 96
Query: 281 VTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKKL 382
+ G I + V F RP + + S G+ +
Sbjct: 97 LNGERAIHQALVQQGSAFADRPAFASFRVVSGGRSM 132
>AY393998-1|AAQ87875.1| 543|Homo sapiens cytochrome P450, family 1,
subfamily B, polypeptide 1 protein.
Length = 543
Score = 43.2 bits (97), Expect = 0.001
Identities = 24/101 (23%), Positives = 55/101 (54%), Gaps = 2/101 (1%)
Frame = +2
Query: 461 ITIVNILWRLVAGKRYDLEDQRLKKLCSLVMRLFKLVDMSGGILNFLPFLRHFV-PRLIG 637
+ + N++ + G RY +D ++L S + V +G +++ +P+L++F P
Sbjct: 199 VAVANVMSAVCFGCRYSHDDPEFRELLSHNEEFGRTVG-AGSLVDVMPWLQYFPNPVRTV 257
Query: 638 FTELQEIHNALHQYLREIIKEHQXNLQLGA-PKDVIDAFLI 757
F E ++++ ++ + H +L+ GA P+D++DAF++
Sbjct: 258 FREFEQLNRNFSNFILDKFLRHCESLRPGAAPRDMMDAFIL 298
Score = 42.3 bits (95), Expect = 0.002
Identities = 28/96 (29%), Positives = 47/96 (48%), Gaps = 2/96 (2%)
Frame = +2
Query: 101 RRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 280
RR + PPGP P++GN +V + HL + +++YG++ +RLGS +VV
Sbjct: 43 RRRQLRSAPPGPFAWPLIGNAAAV------GQAAHLSFARLARRYGDVFQIRLGSCPIVV 96
Query: 281 VTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKKL 382
+ G I + V F RP + + S G+ +
Sbjct: 97 LNGERAIHQALVQQGSAFADRPAFASFRVVSGGRSM 132
>AL138805-3|CAM27343.1| 448|Homo sapiens cytochrome P450, family
24, subfamily A, polypeptide 1 protein.
Length = 448
Score = 43.2 bits (97), Expect = 0.001
Identities = 19/50 (38%), Positives = 31/50 (62%)
Frame = +2
Query: 128 PGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVV 277
PGPT P++G+LL +LW+ K H + + + +KYG + ++LGS V
Sbjct: 59 PGPTSWPLLGSLLQILWKGGLKKQHDTLVE-YHKKYGKIFRMKLGSFESV 107
>AL138805-2|CAB91829.1| 514|Homo sapiens cytochrome P450, family
24, subfamily A, polypeptide 1 protein.
Length = 514
Score = 43.2 bits (97), Expect = 0.001
Identities = 19/50 (38%), Positives = 31/50 (62%)
Frame = +2
Query: 128 PGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVV 277
PGPT P++G+LL +LW+ K H + + + +KYG + ++LGS V
Sbjct: 59 PGPTSWPLLGSLLQILWKGGLKKQHDTLVE-YHKKYGKIFRMKLGSFESV 107
>AF450132-1|AAM50512.1| 543|Homo sapiens cytochrome P450 CYP1B1
protein.
Length = 543
Score = 43.2 bits (97), Expect = 0.001
Identities = 24/101 (23%), Positives = 55/101 (54%), Gaps = 2/101 (1%)
Frame = +2
Query: 461 ITIVNILWRLVAGKRYDLEDQRLKKLCSLVMRLFKLVDMSGGILNFLPFLRHFV-PRLIG 637
+ + N++ + G RY +D ++L S + V +G +++ +P+L++F P
Sbjct: 199 VAVANVMSAVCFGCRYSHDDPEFRELLSHNEEFGRTVG-AGSLVDVMPWLQYFPNPVRTV 257
Query: 638 FTELQEIHNALHQYLREIIKEHQXNLQLGA-PKDVIDAFLI 757
F E ++++ ++ + H +L+ GA P+D++DAF++
Sbjct: 258 FREFEQLNRNFSNFILDKFLRHCESLRPGAAPRDMMDAFIL 298
Score = 42.3 bits (95), Expect = 0.002
Identities = 28/96 (29%), Positives = 47/96 (48%), Gaps = 2/96 (2%)
Frame = +2
Query: 101 RRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 280
RR + PPGP P++GN +V + HL + +++YG++ +RLGS +VV
Sbjct: 43 RRRQLRSAPPGPFAWPLIGNAAAV------GQAAHLSFARLARRYGDVFQIRLGSCPIVV 96
Query: 281 VTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKKL 382
+ G I + V F RP + + S G+ +
Sbjct: 97 LNGERAIHQALVQQGSAFADRPAFASFRVVSGGRSM 132
>AC009229-2|AAY15039.1| 543|Homo sapiens unknown protein.
Length = 543
Score = 43.2 bits (97), Expect = 0.001
Identities = 24/101 (23%), Positives = 55/101 (54%), Gaps = 2/101 (1%)
Frame = +2
Query: 461 ITIVNILWRLVAGKRYDLEDQRLKKLCSLVMRLFKLVDMSGGILNFLPFLRHFV-PRLIG 637
+ + N++ + G RY +D ++L S + V +G +++ +P+L++F P
Sbjct: 199 VAVANVMSAVCFGCRYSHDDPEFRELLSHNEEFGRTVG-AGSLVDVMPWLQYFPNPVRTV 257
Query: 638 FTELQEIHNALHQYLREIIKEHQXNLQLGA-PKDVIDAFLI 757
F E ++++ ++ + H +L+ GA P+D++DAF++
Sbjct: 258 FREFEQLNRNFSNFILDKFLRHCESLRPGAAPRDMMDAFIL 298
Score = 42.3 bits (95), Expect = 0.002
Identities = 28/96 (29%), Positives = 47/96 (48%), Gaps = 2/96 (2%)
Frame = +2
Query: 101 RRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 280
RR + PPGP P++GN +V + HL + +++YG++ +RLGS +VV
Sbjct: 43 RRRQLRSAPPGPFAWPLIGNAAAV------GQAAHLSFARLARRYGDVFQIRLGSCPIVV 96
Query: 281 VTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKKL 382
+ G I + V F RP + + S G+ +
Sbjct: 97 LNGERAIHQALVQQGSAFADRPAFASFRVVSGGRSM 132
>BC070317-1|AAH70317.1| 162|Homo sapiens CYP2C9 protein protein.
Length = 162
Score = 42.7 bits (96), Expect = 0.001
Identities = 26/73 (35%), Positives = 39/73 (53%), Gaps = 2/73 (2%)
Frame = +2
Query: 125 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIR 304
PPGPTPLP++GN+L + + +L S+ YG + L G +VV+ G E ++
Sbjct: 30 PPGPTPLPVIGNILQIGIKDISKSLTNL-----SKVYGPVFTLYFGLKPIVVLHGYEAVK 84
Query: 305 E--VSNREVFEGR 337
E + E F GR
Sbjct: 85 EALIDLGEEFSGR 97
>BC020754-1|AAH20754.1| 162|Homo sapiens CYP2C9 protein protein.
Length = 162
Score = 42.7 bits (96), Expect = 0.001
Identities = 26/73 (35%), Positives = 39/73 (53%), Gaps = 2/73 (2%)
Frame = +2
Query: 125 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIR 304
PPGPTPLP++GN+L + + +L S+ YG + L G +VV+ G E ++
Sbjct: 30 PPGPTPLPVIGNILQIGIKDISKSLTNL-----SKVYGPVFTLYFGLKPIVVLHGYEAVK 84
Query: 305 E--VSNREVFEGR 337
E + E F GR
Sbjct: 85 EALIDLGEEFSGR 97
>AB209700-1|BAD92937.1| 336|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 1 variant protein.
Length = 336
Score = 42.7 bits (96), Expect = 0.001
Identities = 30/124 (24%), Positives = 55/124 (44%), Gaps = 3/124 (2%)
Frame = +2
Query: 401 LVQLRLADAGEPILVNQMFHITIVNILWRLVAGKRYDLEDQRLKKLCSLVMRLFKLVDMS 580
LV L G+P + N++ ++ K +D D++ +L L F L+
Sbjct: 50 LVALTACFVGQPFDPTFLIGCAPCNVIADILFRKHFDYNDEKFLRLMYLFNENFHLLSTP 109
Query: 581 G-GILNFLPFLRHFVPRLIGFTELQEIHNA--LHQYLREIIKEHQXNLQLGAPKDVIDAF 751
+ N P H++P + + I N + +Y+ E +KEH +L P+D+ D
Sbjct: 110 WLQLYNNFPSFLHYLPG----SHRKVIKNVAEVKEYVSERVKEHHQSLDPNCPRDLTDCL 165
Query: 752 LIDM 763
L++M
Sbjct: 166 LVEM 169
>S63426-1|ABB76283.1| 214|Homo sapiens (S)-mephenytoin hydroxylase
associated cytochrome P450 protein.
Length = 214
Score = 42.3 bits (95), Expect = 0.002
Identities = 30/89 (33%), Positives = 44/89 (49%), Gaps = 2/89 (2%)
Frame = +2
Query: 125 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIR 304
P GPTPLPI+GN+L + K ++S+ YG + + G +VV+ G E ++
Sbjct: 30 PSGPTPLPIIGNILQL-----DVKDMSKSLTNFSKVYGPVFTVYFGLKPIVVLHGYEAVK 84
Query: 305 E--VSNREVFEGRPDGFFYTMRSFGKKLG 385
E + + E F GR G F K LG
Sbjct: 85 EALIDHGEEFSGR--GSFPVAEKVNKGLG 111
>DQ359216-1|ABC95161.1| 347|Homo sapiens dioxin-inducible
cytochrome P450 protein.
Length = 347
Score = 42.3 bits (95), Expect = 0.002
Identities = 28/96 (29%), Positives = 47/96 (48%), Gaps = 2/96 (2%)
Frame = +2
Query: 101 RRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 280
RR + PPGP P++GN +V + HL + +++YG++ +RLGS +VV
Sbjct: 43 RRRQLRSAPPGPFAWPLIGNAAAV------GQAAHLSFARLARRYGDVFQIRLGSCPIVV 96
Query: 281 VTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKKL 382
+ G I + V F RP + + S G+ +
Sbjct: 97 LNGERAIHQALVQQGSAFADRPAFASFRVVSGGRSM 132
>DQ211355-2|ABB01373.1| 117|Homo sapiens cytochrome P450 2D6
protein.
Length = 117
Score = 42.3 bits (95), Expect = 0.002
Identities = 31/96 (32%), Positives = 50/96 (52%), Gaps = 3/96 (3%)
Frame = +2
Query: 101 RRHRGLC-YPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVV 277
RR R Y PGP PLP +GNLL V +++ + C + +++G++ L+L VV
Sbjct: 25 RRQRWAARYSPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWTPVV 79
Query: 278 VVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKK 379
V+ G+ +RE V++ E RP + FG +
Sbjct: 80 VLNGLAAVREALVTHGEDTADRPPVPITQILGFGPR 115
>BT020001-1|AAV38804.1| 543|Homo sapiens cytochrome P450, family 1,
subfamily B, polypeptide 1 protein.
Length = 543
Score = 42.3 bits (95), Expect = 0.002
Identities = 28/96 (29%), Positives = 47/96 (48%), Gaps = 2/96 (2%)
Frame = +2
Query: 101 RRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 280
RR + PPGP P++GN +V + HL + +++YG++ +RLGS +VV
Sbjct: 43 RRRQLRSAPPGPFAWPLIGNAAAV------GQAAHLSFARLARRYGDVFQIRLGSCPIVV 96
Query: 281 VTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKKL 382
+ G I + V F RP + + S G+ +
Sbjct: 97 LNGERAIHQALVQQGSAFADRPAFASFRVVSGGRSM 132
Score = 42.3 bits (95), Expect = 0.002
Identities = 24/101 (23%), Positives = 55/101 (54%), Gaps = 2/101 (1%)
Frame = +2
Query: 461 ITIVNILWRLVAGKRYDLEDQRLKKLCSLVMRLFKLVDMSGGILNFLPFLRHFV-PRLIG 637
+ + N++ + G RY +D ++L S + V +G +++ +P+L++F P
Sbjct: 199 VAMANVMSAVCFGCRYSHDDPEFRELLSHNEEFGRTVG-AGSLVDVMPWLQYFPNPVRTV 257
Query: 638 FTELQEIHNALHQYLREIIKEHQXNLQLGA-PKDVIDAFLI 757
F E ++++ ++ + H +L+ GA P+D++DAF++
Sbjct: 258 FREFEQLNRNFSSFILDKFLRHCESLRPGAAPRDMMDAFIL 298
>BC096260-1|AAH96260.1| 431|Homo sapiens CYP2C18 protein protein.
Length = 431
Score = 42.3 bits (95), Expect = 0.002
Identities = 30/89 (33%), Positives = 44/89 (49%), Gaps = 2/89 (2%)
Frame = +2
Query: 125 PPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIR 304
P GPTPLPI+GN+L + K ++S+ YG + + G +VV+ G E ++
Sbjct: 30 PSGPTPLPIIGNILQL-----DVKDMSKSLTNFSKVYGPVFTVYFGLKPIVVLHGYEAVK 84
Query: 305 E--VSNREVFEGRPDGFFYTMRSFGKKLG 385
E + + E F GR G F K LG
Sbjct: 85 EALIDHGEEFSGR--GSFPVAEKVNKGLG 111
>M33189-1|AAA35737.1| 500|Homo sapiens protein ( Human debrisoquine
4-hydroxylase mutant allele (CYP2D6-MA1) gene, complete
cds. ).
Length = 500
Score = 41.9 bits (94), Expect = 0.003
Identities = 31/96 (32%), Positives = 49/96 (51%), Gaps = 3/96 (3%)
Frame = +2
Query: 101 RRHRGLC-YPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVV 277
RR R Y PGP PLP +GNLL V +++ + C + +++G++ L+L VV
Sbjct: 25 RRQRWAARYSPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWTPVV 79
Query: 278 VVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKK 379
V+ G+ +RE V+ E RP + FG +
Sbjct: 80 VLNGLAAVREAMVTRGEDTADRPPVPITQILGFGPR 115
>J04813-1|AAA02993.1| 502|Homo sapiens cytochrome P450 PCN3
protein.
Length = 502
Score = 41.5 bits (93), Expect = 0.003
Identities = 25/69 (36%), Positives = 39/69 (56%), Gaps = 2/69 (2%)
Frame = +2
Query: 128 PGPTPLPIVGNLLSVLWESRKF--KCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELI 301
PGPTPLP++GN+LS KF +C+ +KYG + G G + V+ +T ++I
Sbjct: 39 PGPTPLPLLGNVLSYRQGLWKFDTECY--------KKYGKMWGTYEGQLPVLAITDPDVI 90
Query: 302 REVSNREVF 328
R V +E +
Sbjct: 91 RTVLVKECY 99
>DQ680079-1|ABG25922.1| 347|Homo sapiens truncated cytochrome P450,
family 3, subfamily A, polypeptide 5 protein.
Length = 347
Score = 41.5 bits (93), Expect = 0.003
Identities = 25/69 (36%), Positives = 39/69 (56%), Gaps = 2/69 (2%)
Frame = +2
Query: 128 PGPTPLPIVGNLLSVLWESRKF--KCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELI 301
PGPTPLP++GN+LS KF +C+ +KYG + G G + V+ +T ++I
Sbjct: 39 PGPTPLPLLGNVLSYRQGLWKFDTECY--------KKYGKMWGTYEGQLPVLAITDPDVI 90
Query: 302 REVSNREVF 328
R V +E +
Sbjct: 91 RTVLVKECY 99
>DQ372705-1|ABD16216.1| 150|Homo sapiens mutant cytochrome p450
protein.
Length = 150
Score = 41.5 bits (93), Expect = 0.003
Identities = 26/82 (31%), Positives = 41/82 (50%), Gaps = 2/82 (2%)
Frame = +2
Query: 101 RRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 280
RR + PPGP P++GN +V + HL + +++YG++ +RLGS +VV
Sbjct: 43 RRRQLRSAPPGPFAWPLIGNAAAV------GQAAHLSFARLARRYGDVFQIRLGSCPIVV 96
Query: 281 VTGIELIRE--VSNREVFEGRP 340
+ G I + V F RP
Sbjct: 97 LNGERAIHQALVQQGSAFADRP 118
>BC033862-1|AAH33862.1| 502|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 5 protein.
Length = 502
Score = 41.5 bits (93), Expect = 0.003
Identities = 25/69 (36%), Positives = 39/69 (56%), Gaps = 2/69 (2%)
Frame = +2
Query: 128 PGPTPLPIVGNLLSVLWESRKF--KCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELI 301
PGPTPLP++GN+LS KF +C+ +KYG + G G + V+ +T ++I
Sbjct: 39 PGPTPLPLLGNVLSYRQGLWKFDTECY--------KKYGKMWGTYEGQLPVLAITDPDVI 90
Query: 302 REVSNREVF 328
R V +E +
Sbjct: 91 RTVLVKECY 99
>AK223008-1|BAD96728.1| 502|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 5 variant protein.
Length = 502
Score = 41.5 bits (93), Expect = 0.003
Identities = 25/69 (36%), Positives = 39/69 (56%), Gaps = 2/69 (2%)
Frame = +2
Query: 128 PGPTPLPIVGNLLSVLWESRKF--KCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELI 301
PGPTPLP++GN+LS KF +C+ +KYG + G G + V+ +T ++I
Sbjct: 39 PGPTPLPLLGNVLSYRQGLWKFDTECY--------KKYGKMWGTYEGQLPVLAITDPDVI 90
Query: 302 REVSNREVF 328
R V +E +
Sbjct: 91 RTVLVKECY 99
>AF280107-4|AAG32288.1| 106|Homo sapiens cytochrome P450
polypeptide 5 protein.
Length = 106
Score = 41.5 bits (93), Expect = 0.003
Identities = 25/69 (36%), Positives = 39/69 (56%), Gaps = 2/69 (2%)
Frame = +2
Query: 128 PGPTPLPIVGNLLSVLWESRKF--KCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELI 301
PGPTPLP++GN+LS KF +C+ +KYG + G G + V+ +T ++I
Sbjct: 39 PGPTPLPLLGNVLSYRQGLWKFDTECY--------KKYGKMWGTYEGQLPVLAITDPDVI 90
Query: 302 REVSNREVF 328
R V +E +
Sbjct: 91 RTVLVKECY 99
>AC005020-1|AAS02016.1| 502|Homo sapiens unknown protein.
Length = 502
Score = 41.5 bits (93), Expect = 0.003
Identities = 25/69 (36%), Positives = 39/69 (56%), Gaps = 2/69 (2%)
Frame = +2
Query: 128 PGPTPLPIVGNLLSVLWESRKF--KCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELI 301
PGPTPLP++GN+LS KF +C+ +KYG + G G + V+ +T ++I
Sbjct: 39 PGPTPLPLLGNVLSYRQGLWKFDTECY--------KKYGKMWGTYEGQLPVLAITDPDVI 90
Query: 302 REVSNREVF 328
R V +E +
Sbjct: 91 RTVLVKECY 99
>L13286-1|AAA62379.1| 513|Homo sapiens 1,25-dihydroxyvitamin D3
24-hydroxylase protein.
Length = 513
Score = 40.7 bits (91), Expect = 0.006
Identities = 18/50 (36%), Positives = 30/50 (60%)
Frame = +2
Query: 128 PGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVV 277
PGPT P++ +LL +LW+ K H + + + +KYG + ++LGS V
Sbjct: 59 PGPTSWPLLASLLQILWKGGLKKQHDTLVE-YHKKYGKIFRMKLGSFESV 107
>AF171066-1|AAG43404.1| 112|Homo sapiens CYP1B1 variant protein.
Length = 112
Score = 39.1 bits (87), Expect = 0.018
Identities = 23/69 (33%), Positives = 37/69 (53%)
Frame = +2
Query: 101 RRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 280
RR G PPGP P++GN +V + HL + +++YG++ +RLGS +VV
Sbjct: 44 RRQLGSA-PPGPFAWPLIGNAAAV------GQAAHLSFARLARRYGDVFQIRLGSCPIVV 96
Query: 281 VTGIELIRE 307
+ G I +
Sbjct: 97 LNGERAIHQ 105
>J04449-1|AAA35747.1| 502|Homo sapiens cytochrome P450 nifedipine
oxidase protein.
Length = 502
Score = 37.9 bits (84), Expect = 0.042
Identities = 23/67 (34%), Positives = 35/67 (52%)
Frame = +2
Query: 128 PGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIRE 307
PGPTPLP +GN+LS K C + +KYG + G G V+ +T ++I+
Sbjct: 39 PGPTPLPFLGNILSY----HKGFC--MFDMECHKKYGKVCGFYDGQQPVLAITDPDMIKT 92
Query: 308 VSNREVF 328
V +E +
Sbjct: 93 VLVKECY 99
>BC012027-1|AAH12027.1| 168|Homo sapiens CYP2U1 protein protein.
Length = 168
Score = 37.9 bits (84), Expect = 0.042
Identities = 31/100 (31%), Positives = 44/100 (44%), Gaps = 20/100 (20%)
Frame = +2
Query: 101 RRHRGLCYPPGPTPLPIVGNLLSVL---------WESRKFKC---------HHLIWQSWS 226
RR R PPGPTP P+VGN VL W S + + ++ +
Sbjct: 52 RRRRARGIPPGPTPWPLVGNFGHVLLPPFLRRRSWLSSRTRAAGIDPSVIGPQVLLAHLA 111
Query: 227 QKYGNLLGLRLGSINVVVVTGIELIRE--VSNREVFEGRP 340
+ YG++ +G VVV++ +RE V EVF RP
Sbjct: 112 RVYGSIFSFFIGHYLVVVLSDFHSVREALVQQAEVFSDRP 151
>X12387-1|CAA30944.1| 503|Homo sapiens protein ( Human mRNA for
cytochrome P-450 (cyp3 locus). ).
Length = 503
Score = 37.5 bits (83), Expect = 0.056
Identities = 23/67 (34%), Positives = 35/67 (52%)
Frame = +2
Query: 128 PGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIRE 307
PGPTPLP +GN+LS K C + +KYG + G G V+ +T ++I+
Sbjct: 39 PGPTPLPFLGNILSY----HKGFC--MFDMECHKKYGKVWGFYDGQQPVLAITDPDMIKT 92
Query: 308 VSNREVF 328
V +E +
Sbjct: 93 VLVKECY 99
>M18907-1|AAA35745.1| 503|Homo sapiens protein ( Human P450 mRNA
encoding nifedipine oxidase, complete cds. ).
Length = 503
Score = 37.5 bits (83), Expect = 0.056
Identities = 23/67 (34%), Positives = 35/67 (52%)
Frame = +2
Query: 128 PGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIRE 307
PGPTPLP +GN+LS K C + +KYG + G G V+ +T ++I+
Sbjct: 39 PGPTPLPFLGNILSY----HKGFC--MFDMECHKKYGKVWGFYDGQQPVLAITDPDMIKT 92
Query: 308 VSNREVF 328
V +E +
Sbjct: 93 VLVKECY 99
>M14096-1|AAA35744.1| 503|Homo sapiens protein ( Human cytochrome
P-450 nifedipine oxidase mRNA, complet cds. ).
Length = 503
Score = 37.5 bits (83), Expect = 0.056
Identities = 23/67 (34%), Positives = 35/67 (52%)
Frame = +2
Query: 128 PGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIRE 307
PGPTPLP +GN+LS K C + +KYG + G G V+ +T ++I+
Sbjct: 39 PGPTPLPFLGNILSY----HKGFC--MFDMECHKKYGKVWGFYDGQQPVLAITDPDMIKT 92
Query: 308 VSNREVF 328
V +E +
Sbjct: 93 VLVKECY 99
>K03192-1|AAA52147.1| 331|Homo sapiens CYP1A1 protein.
Length = 331
Score = 37.5 bits (83), Expect = 0.056
Identities = 26/110 (23%), Positives = 54/110 (49%), Gaps = 1/110 (0%)
Frame = +2
Query: 464 TIVNILWRLVAGKRYDLEDQRLKKLCSLVMRLFKL-VDMSGGILNFLPFLRHFVPRLIGF 640
T N++ +V G R+D +D+ L L +++ + + V+ +G + + +P
Sbjct: 15 TFSNVISSIVFGDRFDYKDRELLSLFRIMLVIVPVHVNSTGQLYEMFSSVMKQLPG--PQ 72
Query: 641 TELQEIHNALHQYLREIIKEHQXNLQLGAPKDVIDAFLIDMLESQXDKLT 790
+ ++ L ++ + + EH L +P+D ID+FLI M E + + T
Sbjct: 73 QQAFQLLQGLEDFIAKKV-EHNTPLDPNSPRDFIDSFLIRMQEEEKNPNT 121
>DQ924960-1|ABI96208.1| 503|Homo sapiens cytochrome P450 family 3
subfamily A polypeptide 4 protein.
Length = 503
Score = 37.5 bits (83), Expect = 0.056
Identities = 23/67 (34%), Positives = 35/67 (52%)
Frame = +2
Query: 128 PGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIRE 307
PGPTPLP +GN+LS K C + +KYG + G G V+ +T ++I+
Sbjct: 39 PGPTPLPFLGNILSY----HKGFC--MFDMECHKKYGKVWGFYDGQQPVLAITDPDMIKT 92
Query: 308 VSNREVF 328
V +E +
Sbjct: 93 VLVKECY 99
>DQ005611-1|AAY16980.1| 503|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 4 protein.
Length = 503
Score = 37.5 bits (83), Expect = 0.056
Identities = 23/67 (34%), Positives = 35/67 (52%)
Frame = +2
Query: 128 PGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIRE 307
PGPTPLP +GN+LS K C + +KYG + G G V+ +T ++I+
Sbjct: 39 PGPTPLPFLGNILSY----HKGFC--MFDMECHKKYGKVWGFYDGQQPVLAITDPDMIKT 92
Query: 308 VSNREVF 328
V +E +
Sbjct: 93 VLVKECY 99
>BC101631-1|AAI01632.1| 503|Homo sapiens cytochrome P450, subfamily
IIIA, polypeptide 4 protein.
Length = 503
Score = 37.5 bits (83), Expect = 0.056
Identities = 23/67 (34%), Positives = 35/67 (52%)
Frame = +2
Query: 128 PGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIRE 307
PGPTPLP +GN+LS K C + +KYG + G G V+ +T ++I+
Sbjct: 39 PGPTPLPFLGNILSY----HKGFC--MFDMECHKKYGKVWGFYDGQQPVLAITDPDMIKT 92
Query: 308 VSNREVF 328
V +E +
Sbjct: 93 VLVKECY 99
>BC069418-1|AAH69418.1| 503|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 4 protein.
Length = 503
Score = 37.5 bits (83), Expect = 0.056
Identities = 23/67 (34%), Positives = 35/67 (52%)
Frame = +2
Query: 128 PGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIRE 307
PGPTPLP +GN+LS K C + +KYG + G G V+ +T ++I+
Sbjct: 39 PGPTPLPFLGNILSY----HKGFC--MFDMECHKKYGKVWGFYDGQQPVLAITDPDMIKT 92
Query: 308 VSNREVF 328
V +E +
Sbjct: 93 VLVKECY 99
>AJ563375-1|CAD91343.1| 503|Homo sapiens cytochrome P450 protein.
Length = 503
Score = 37.5 bits (83), Expect = 0.056
Identities = 23/67 (34%), Positives = 35/67 (52%)
Frame = +2
Query: 128 PGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIRE 307
PGPTPLP +GN+LS K C + +KYG + G G V+ +T ++I+
Sbjct: 39 PGPTPLPFLGNILSY----HKGFC--MFDMECHKKYGKVWGFYDGQQPVLAITDPDMIKT 92
Query: 308 VSNREVF 328
V +E +
Sbjct: 93 VLVKECY 99
>AF280107-2|AAG32290.1| 503|Homo sapiens cytochrome P450
polypeptide 4 protein.
Length = 503
Score = 37.5 bits (83), Expect = 0.056
Identities = 23/67 (34%), Positives = 35/67 (52%)
Frame = +2
Query: 128 PGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIRE 307
PGPTPLP +GN+LS K C + +KYG + G G V+ +T ++I+
Sbjct: 39 PGPTPLPFLGNILSY----HKGFC--MFDMECHKKYGKVWGFYDGQQPVLAITDPDMIKT 92
Query: 308 VSNREVF 328
V +E +
Sbjct: 93 VLVKECY 99
>AF209389-1|AAF21034.1| 503|Homo sapiens cytochrome P450 IIIA4
protein.
Length = 503
Score = 37.5 bits (83), Expect = 0.056
Identities = 23/67 (34%), Positives = 35/67 (52%)
Frame = +2
Query: 128 PGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIRE 307
PGPTPLP +GN+LS K C + +KYG + G G V+ +T ++I+
Sbjct: 39 PGPTPLPFLGNILSY----HKGFC--MFDMECHKKYGKVWGFYDGQQPVLAITDPDMIKT 92
Query: 308 VSNREVF 328
V +E +
Sbjct: 93 VLVKECY 99
>AF182273-1|AAF13598.1| 503|Homo sapiens cytochrome P450-3A4
protein.
Length = 503
Score = 37.5 bits (83), Expect = 0.056
Identities = 23/67 (34%), Positives = 35/67 (52%)
Frame = +2
Query: 128 PGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIRE 307
PGPTPLP +GN+LS K C + +KYG + G G V+ +T ++I+
Sbjct: 39 PGPTPLPFLGNILSY----HKGFC--MFDMECHKKYGKVWGFYDGQQPVLAITDPDMIKT 92
Query: 308 VSNREVF 328
V +E +
Sbjct: 93 VLVKECY 99
>M13785-1|AAA35742.1| 504|Homo sapiens protein ( Human liver
glucocorticoid-inducible cytochrome P-450 (HLp) mRNA,
complete cds. ).
Length = 504
Score = 36.7 bits (81), Expect = 0.098
Identities = 23/67 (34%), Positives = 35/67 (52%)
Frame = +2
Query: 128 PGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIRE 307
PGPTPLP +GN+LS K C + +KYG + G G V+ +T ++I+
Sbjct: 39 PGPTPLPFLGNILSY----HKGFC--MFDMECHKKYGKVWGFYDGQQPVLAITDPDMIKL 92
Query: 308 VSNREVF 328
V +E +
Sbjct: 93 VLVKECY 99
>D00003-1|BAA00001.1| 504|Homo sapiens cytochrome P-450 protein.
Length = 504
Score = 36.7 bits (81), Expect = 0.098
Identities = 23/67 (34%), Positives = 35/67 (52%)
Frame = +2
Query: 128 PGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIRE 307
PGPTPLP +GN+LS K C + +KYG + G G V+ +T ++I+
Sbjct: 39 PGPTPLPFLGNILSY----HKGFC--MFDMECHKKYGKVWGFYDGQQPVLAITDPDMIKL 92
Query: 308 VSNREVF 328
V +E +
Sbjct: 93 VLVKECY 99
>AB209492-1|BAD92729.1| 566|Homo sapiens Debrisoquine 4-hydroxylase
mutant allele variant protein.
Length = 566
Score = 30.3 bits (65), Expect(2) = 0.21
Identities = 15/32 (46%), Positives = 20/32 (62%), Gaps = 1/32 (3%)
Frame = +2
Query: 101 RRHRGLC-YPPGPTPLPIVGNLLSVLWESRKF 193
RR R Y PGP PLP +GNLL V +++ +
Sbjct: 62 RRQRWAARYSPGPLPLPGLGNLLHVDFQNTPY 93
Score = 24.2 bits (50), Expect(2) = 0.21
Identities = 15/53 (28%), Positives = 27/53 (50%), Gaps = 2/53 (3%)
Frame = +2
Query: 227 QKYGNLLGLRLGSINVVVVTGIELIRE--VSNREVFEGRPDGFFYTMRSFGKK 379
+++G++ L+L VVV+ G+ +RE V+ E RP + FG +
Sbjct: 133 RRFGDVFSLQLAWTPVVVLNGLAAVREAMVTRGEDTADRPPVPITQILGFGPR 185
>X54807-1|CAA38578.1| 56|Homo sapiens unspecific monooxygenase
protein.
Length = 56
Score = 35.5 bits (78), Expect = 0.23
Identities = 12/16 (75%), Positives = 15/16 (93%)
Frame = +2
Query: 125 PPGPTPLPIVGNLLSV 172
PPGPTPLPI+GN+L +
Sbjct: 30 PPGPTPLPIIGNMLQI 45
>AY390425-1|AAQ92353.1| 503|Homo sapiens cytochrome P450 CYP3A43.1
protein.
Length = 503
Score = 35.5 bits (78), Expect = 0.23
Identities = 21/67 (31%), Positives = 35/67 (52%)
Frame = +2
Query: 128 PGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIRE 307
PGPTPLP +G +L L F + ++KYG + GL G ++V+ ++I+
Sbjct: 39 PGPTPLPFLGTILFYLRGLWNFD------RECNEKYGEMWGLYEGQQPMLVIMDPDMIKT 92
Query: 308 VSNREVF 328
V +E +
Sbjct: 93 VLVKECY 99
>AY390424-1|AAQ92352.1| 503|Homo sapiens cytochrome P450 CYP3A43.3
protein.
Length = 503
Score = 35.5 bits (78), Expect = 0.23
Identities = 21/67 (31%), Positives = 35/67 (52%)
Frame = +2
Query: 128 PGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIRE 307
PGPTPLP +G +L L F + ++KYG + GL G ++V+ ++I+
Sbjct: 39 PGPTPLPFLGTILFYLRGLWNFD------RECNEKYGEMWGLYEGQQPMLVIMDPDMIKT 92
Query: 308 VSNREVF 328
V +E +
Sbjct: 93 VLVKECY 99
>AF337813-1|AAK38841.1| 503|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 503
Score = 35.5 bits (78), Expect = 0.23
Identities = 21/67 (31%), Positives = 35/67 (52%)
Frame = +2
Query: 128 PGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIRE 307
PGPTPLP +G +L L F + ++KYG + GL G ++V+ ++I+
Sbjct: 39 PGPTPLPFLGTILFYLRGLWNFD------RECNEKYGEMWGLYEGQQPMLVIMDPDMIKT 92
Query: 308 VSNREVF 328
V +E +
Sbjct: 93 VLVKECY 99
>AF319634-1|AAK00325.1| 503|Homo sapiens cytochrome P450 CYP3A43
protein.
Length = 503
Score = 35.5 bits (78), Expect = 0.23
Identities = 21/67 (31%), Positives = 35/67 (52%)
Frame = +2
Query: 128 PGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIRE 307
PGPTPLP +G +L L F + ++KYG + GL G ++V+ ++I+
Sbjct: 39 PGPTPLPFLGTILFYLRGLWNFD------RECNEKYGEMWGLYEGQQPMLVIMDPDMIKT 92
Query: 308 VSNREVF 328
V +E +
Sbjct: 93 VLVKECY 99
>AF280111-1|AAG33012.1| 250|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 250
Score = 35.5 bits (78), Expect = 0.23
Identities = 21/67 (31%), Positives = 35/67 (52%)
Frame = +2
Query: 128 PGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIRE 307
PGPTPLP +G +L L F + ++KYG + GL G ++V+ ++I+
Sbjct: 39 PGPTPLPFLGTILFYLRGLWNFD------RECNEKYGEMWGLYEGQQPMLVIMDPDMIKT 92
Query: 308 VSNREVF 328
V +E +
Sbjct: 93 VLVKECY 99
>AF280110-1|AAG33011.1| 420|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 420
Score = 35.5 bits (78), Expect = 0.23
Identities = 21/67 (31%), Positives = 35/67 (52%)
Frame = +2
Query: 128 PGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIRE 307
PGPTPLP +G +L L F + ++KYG + GL G ++V+ ++I+
Sbjct: 39 PGPTPLPFLGTILFYLRGLWNFD------RECNEKYGEMWGLYEGQQPMLVIMDPDMIKT 92
Query: 308 VSNREVF 328
V +E +
Sbjct: 93 VLVKECY 99
>AF280109-1|AAG33010.1| 504|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 504
Score = 35.5 bits (78), Expect = 0.23
Identities = 21/67 (31%), Positives = 35/67 (52%)
Frame = +2
Query: 128 PGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIRE 307
PGPTPLP +G +L L F + ++KYG + GL G ++V+ ++I+
Sbjct: 39 PGPTPLPFLGTILFYLRGLWNFD------RECNEKYGEMWGLYEGQQPMLVIMDPDMIKT 92
Query: 308 VSNREVF 328
V +E +
Sbjct: 93 VLVKECY 99
>AF280108-1|AAG33009.1| 503|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 503
Score = 35.5 bits (78), Expect = 0.23
Identities = 21/67 (31%), Positives = 35/67 (52%)
Frame = +2
Query: 128 PGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIRE 307
PGPTPLP +G +L L F + ++KYG + GL G ++V+ ++I+
Sbjct: 39 PGPTPLPFLGTILFYLRGLWNFD------RECNEKYGEMWGLYEGQQPMLVIMDPDMIKT 92
Query: 308 VSNREVF 328
V +E +
Sbjct: 93 VLVKECY 99
>AF280107-1|AAG32291.1| 106|Homo sapiens cytochrome P450
polypeptide 43 protein.
Length = 106
Score = 35.5 bits (78), Expect = 0.23
Identities = 21/67 (31%), Positives = 35/67 (52%)
Frame = +2
Query: 128 PGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIRE 307
PGPTPLP +G +L L F + ++KYG + GL G ++V+ ++I+
Sbjct: 39 PGPTPLPFLGTILFYLRGLWNFD------RECNEKYGEMWGLYEGQQPMLVIMDPDMIKT 92
Query: 308 VSNREVF 328
V +E +
Sbjct: 93 VLVKECY 99
>AC011904-5|AAS07394.1| 504|Homo sapiens unknown protein.
Length = 504
Score = 35.5 bits (78), Expect = 0.23
Identities = 21/67 (31%), Positives = 35/67 (52%)
Frame = +2
Query: 128 PGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIRE 307
PGPTPLP +G +L L F + ++KYG + GL G ++V+ ++I+
Sbjct: 39 PGPTPLPFLGTILFYLRGLWNFD------RECNEKYGEMWGLYEGQQPMLVIMDPDMIKT 92
Query: 308 VSNREVF 328
V +E +
Sbjct: 93 VLVKECY 99
>AC011904-4|AAS07395.1| 503|Homo sapiens unknown protein.
Length = 503
Score = 35.5 bits (78), Expect = 0.23
Identities = 21/67 (31%), Positives = 35/67 (52%)
Frame = +2
Query: 128 PGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIRE 307
PGPTPLP +G +L L F + ++KYG + GL G ++V+ ++I+
Sbjct: 39 PGPTPLPFLGTILFYLRGLWNFD------RECNEKYGEMWGLYEGQQPMLVIMDPDMIKT 92
Query: 308 VSNREVF 328
V +E +
Sbjct: 93 VLVKECY 99
>M63871-1|AAA59984.1| 508|Homo sapiens CYP17 protein.
Length = 508
Score = 34.3 bits (75), Expect = 0.52
Identities = 26/82 (31%), Positives = 41/82 (50%), Gaps = 2/82 (2%)
Frame = +2
Query: 101 RRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 280
RR G YP LP+VG+L + R H+ ++ +KYG + +R+G+ V+
Sbjct: 20 RRWPGAKYPKSLLSLPLVGSLPFL---PRHGHMHNNFFKL-QKKYGPIYSVRMGTKTTVI 75
Query: 281 VTGIELIREV--SNREVFEGRP 340
V +L +EV + F GRP
Sbjct: 76 VGHHQLAKEVLIKKGKDFSGRP 97
>M19489-1|AAA36405.1| 508|Homo sapiens CYP17 protein.
Length = 508
Score = 34.3 bits (75), Expect = 0.52
Identities = 26/82 (31%), Positives = 41/82 (50%), Gaps = 2/82 (2%)
Frame = +2
Query: 101 RRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 280
RR G YP LP+VG+L + R H+ ++ +KYG + +R+G+ V+
Sbjct: 20 RRWPGAKYPKSLLSLPLVGSLPFL---PRHGHMHNNFFKL-QKKYGPIYSVRMGTKTTVI 75
Query: 281 VTGIELIREV--SNREVFEGRP 340
V +L +EV + F GRP
Sbjct: 76 VGHHQLAKEVLIKKGKDFSGRP 97
>M31153-1|AAA52140.1| 508|Homo sapiens CYP17 protein.
Length = 508
Score = 33.9 bits (74), Expect = 0.69
Identities = 26/82 (31%), Positives = 41/82 (50%), Gaps = 2/82 (2%)
Frame = +2
Query: 101 RRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 280
RR G YP LP+VG+L + R H+ ++ +KYG + +R+G+ V+
Sbjct: 20 RRCPGAKYPKSLLSLPLVGSLPFL---PRHGHMHNNFFKL-QKKYGPIYSVRMGTKTTVI 75
Query: 281 VTGIELIREV--SNREVFEGRP 340
V +L +EV + F GRP
Sbjct: 76 VGHHQLAKEVLIKKGKDFSGRP 97
>M14564-1|AAA52151.1| 508|Homo sapiens CYP17 protein.
Length = 508
Score = 33.9 bits (74), Expect = 0.69
Identities = 26/82 (31%), Positives = 41/82 (50%), Gaps = 2/82 (2%)
Frame = +2
Query: 101 RRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 280
RR G YP LP+VG+L + R H+ ++ +KYG + +R+G+ V+
Sbjct: 20 RRCPGAKYPKSLLSLPLVGSLPFL---PRHGHMHNNFFKL-QKKYGPIYSVRMGTKTTVI 75
Query: 281 VTGIELIREV--SNREVFEGRP 340
V +L +EV + F GRP
Sbjct: 76 VGHHQLAKEVLIKKGKDFSGRP 97
>DQ530598-1|ABF50972.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 33.9 bits (74), Expect = 0.69
Identities = 26/82 (31%), Positives = 41/82 (50%), Gaps = 2/82 (2%)
Frame = +2
Query: 101 RRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 280
RR G YP LP+VG+L + R H+ ++ +KYG + +R+G+ V+
Sbjct: 20 RRCPGAKYPKSLLSLPLVGSLPFL---PRHGHMHNNFFKL-QKKYGPIYSVRMGTKTTVI 75
Query: 281 VTGIELIREV--SNREVFEGRP 340
V +L +EV + F GRP
Sbjct: 76 VGHHQLAKEVLIKKGKDFSGRP 97
>BT020000-1|AAV38803.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 33.9 bits (74), Expect = 0.69
Identities = 26/82 (31%), Positives = 41/82 (50%), Gaps = 2/82 (2%)
Frame = +2
Query: 101 RRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 280
RR G YP LP+VG+L + R H+ ++ +KYG + +R+G+ V+
Sbjct: 20 RRCPGAKYPKSLLSLPLVGSLPFL---PRHGHMHNNFFKL-QKKYGPIYSVRMGTKTTVI 75
Query: 281 VTGIELIREV--SNREVFEGRP 340
V +L +EV + F GRP
Sbjct: 76 VGHHQLAKEVLIKKGKDFSGRP 97
>BC063388-1|AAH63388.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 33.9 bits (74), Expect = 0.69
Identities = 26/82 (31%), Positives = 41/82 (50%), Gaps = 2/82 (2%)
Frame = +2
Query: 101 RRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 280
RR G YP LP+VG+L + R H+ ++ +KYG + +R+G+ V+
Sbjct: 20 RRCPGAKYPKSLLSLPLVGSLPFL---PRHGHMHNNFFKL-QKKYGPIYSVRMGTKTTVI 75
Query: 281 VTGIELIREV--SNREVFEGRP 340
V +L +EV + F GRP
Sbjct: 76 VGHHQLAKEVLIKKGKDFSGRP 97
>BC062997-1|AAH62997.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 33.9 bits (74), Expect = 0.69
Identities = 26/82 (31%), Positives = 41/82 (50%), Gaps = 2/82 (2%)
Frame = +2
Query: 101 RRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 280
RR G YP LP+VG+L + R H+ ++ +KYG + +R+G+ V+
Sbjct: 20 RRCPGAKYPKSLLSLPLVGSLPFL---PRHGHMHNNFFKL-QKKYGPIYSVRMGTKTTVI 75
Query: 281 VTGIELIREV--SNREVFEGRP 340
V +L +EV + F GRP
Sbjct: 76 VGHHQLAKEVLIKKGKDFSGRP 97
>AL358790-3|CAI52498.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 33.9 bits (74), Expect = 0.69
Identities = 26/82 (31%), Positives = 41/82 (50%), Gaps = 2/82 (2%)
Frame = +2
Query: 101 RRHRGLCYPPGPTPLPIVGNLLSVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 280
RR G YP LP+VG+L + R H+ ++ +KYG + +R+G+ V+
Sbjct: 20 RRCPGAKYPKSLLSLPLVGSLPFL---PRHGHMHNNFFKL-QKKYGPIYSVRMGTKTTVI 75
Query: 281 VTGIELIREV--SNREVFEGRP 340
V +L +EV + F GRP
Sbjct: 76 VGHHQLAKEVLIKKGKDFSGRP 97
>X56452-1|CAA39833.1| 56|Homo sapiens unspecific monooxygenase
protein.
Length = 56
Score = 31.5 bits (68), Expect = 3.7
Identities = 11/16 (68%), Positives = 14/16 (87%)
Frame = +2
Query: 125 PPGPTPLPIVGNLLSV 172
P GPTPLPI+GN+L +
Sbjct: 30 PSGPTPLPIIGNILQL 45
>AF081569-1|AAD25924.1| 52|Homo sapiens cytochrome P450 protein.
Length = 52
Score = 31.5 bits (68), Expect = 3.7
Identities = 11/16 (68%), Positives = 14/16 (87%)
Frame = +2
Query: 125 PPGPTPLPIVGNLLSV 172
PPGP PLP++GNLL +
Sbjct: 31 PPGPRPLPLLGNLLQM 46
>EF122244-1|ABO41979.1| 216|Homo sapiens cytochrome P450 2F1
variant protein.
Length = 216
Score = 30.3 bits (65), Expect = 8.5
Identities = 13/41 (31%), Positives = 21/41 (51%)
Frame = +2
Query: 668 LHQYLREIIKEHQXNLQLGAPKDVIDAFLIDMLESQXDKLT 790
L + + +HQ +L +P+D I FL M E + D L+
Sbjct: 26 LRDLIAHSVHDHQASLDPRSPRDFIQCFLTKMAEEKEDPLS 66
>AL512656-1|CAI15290.1| 488|Homo sapiens annexin A7 protein.
Length = 488
Score = 30.3 bits (65), Expect = 8.5
Identities = 16/46 (34%), Positives = 22/46 (47%)
Frame = -2
Query: 384 PSFFPNDLMV*KNPSGLPSNTSRFETSLMSSIPVTTTTLMDPSLKP 247
P FP M + P G P+ S+ T SS PV + +D S +P
Sbjct: 123 PGGFPGGQMPSQYPGGQPTYPSQINTDSFSSYPVFSPVSLDYSSEP 168
>AL353731-3|CAI52484.1| 488|Homo sapiens annexin A7 protein.
Length = 488
Score = 30.3 bits (65), Expect = 8.5
Identities = 16/46 (34%), Positives = 22/46 (47%)
Frame = -2
Query: 384 PSFFPNDLMV*KNPSGLPSNTSRFETSLMSSIPVTTTTLMDPSLKP 247
P FP M + P G P+ S+ T SS PV + +D S +P
Sbjct: 123 PGGFPGGQMPSQYPGGQPTYPSQINTDSFSSYPVFSPVSLDYSSEP 168
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 125,264,072
Number of Sequences: 237096
Number of extensions: 2950714
Number of successful extensions: 6790
Number of sequences better than 10.0: 223
Number of HSP's better than 10.0 without gapping: 6066
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6610
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 9924838204
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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