Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P14_F_M20
(609 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_P11177 Cluster: Pyruvate dehydrogenase E1 component sub... 247 1e-64
UniRef50_Q4UKQ7 Cluster: Pyruvate dehydrogenase E1 component sub... 202 5e-51
UniRef50_Q6N5V4 Cluster: Pyruvate dehydrogenase E1 beta subunit;... 198 6e-50
UniRef50_O66113 Cluster: Pyruvate dehydrogenase E1 component sub... 192 6e-48
UniRef50_Q1VWM3 Cluster: Pyruvate dehydrogenase E1 component, be... 160 3e-38
UniRef50_Q8IML6 Cluster: CG11876-PB, isoform B; n=2; melanogaste... 158 8e-38
UniRef50_A6Q3I5 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 145 6e-34
UniRef50_Q74AE0 Cluster: Dehydrogenase complex, E1 component, be... 139 5e-32
UniRef50_Q8DMB7 Cluster: Pyruvate dehydrogenase E1 component bet... 134 2e-30
UniRef50_A7CXZ3 Cluster: Transketolase central region; n=1; Opit... 130 2e-29
UniRef50_Q98FT4 Cluster: Acetoin dehydrogenase (TPP-dependent) b... 130 3e-29
UniRef50_A6UDY4 Cluster: Transketolase central region; n=1; Sino... 128 1e-28
UniRef50_Q32RM2 Cluster: Pyruvate dehydrogenase E1 component sub... 124 1e-27
UniRef50_A5UU14 Cluster: Transketolase, central region; n=3; Chl... 124 2e-27
UniRef50_A3VIE8 Cluster: Acetoin dehydrogenase (TPP-dependent) b... 123 3e-27
UniRef50_Q5L234 Cluster: Thiamine pyrophosphate-dependent dehydr... 120 2e-26
UniRef50_Q03KN0 Cluster: Pyruvate dehydrogenase (E1) component, ... 120 2e-26
UniRef50_A5V539 Cluster: Transketolase, central region; n=4; Bac... 120 2e-26
UniRef50_P37941 Cluster: 2-oxoisovalerate dehydrogenase subunit ... 120 3e-26
UniRef50_Q3WCG4 Cluster: Transketolase, central region:Transketo... 118 8e-26
UniRef50_P96103 Cluster: Pyruvate dehydrogenase complex E1 beta ... 118 1e-25
UniRef50_UPI000155C0B5 Cluster: PREDICTED: similar to pyruvate d... 115 8e-25
UniRef50_A1SN85 Cluster: Transketolase, central region; n=4; cel... 115 8e-25
UniRef50_A0UXT4 Cluster: Transketolase-like; n=1; Clostridium ce... 115 1e-24
UniRef50_A5V352 Cluster: Transketolase, central region; n=1; Sph... 114 1e-24
UniRef50_Q1AZ53 Cluster: Transketolase, central region; n=1; Rub... 112 5e-24
UniRef50_Q5HKL9 Cluster: Acetoin dehydrogenase, E1 component, be... 111 9e-24
UniRef50_Q5VGY3 Cluster: Pyruvate dehydrogenase beta subunit; n=... 110 2e-23
UniRef50_A0Z5N8 Cluster: Acetoin dehydrogenase E1 component, bet... 110 3e-23
UniRef50_A0LTR0 Cluster: Transketolase, central region; n=2; Act... 109 5e-23
UniRef50_Q97YF5 Cluster: Pyruvate dehydrogenase, beta subunit (L... 109 5e-23
UniRef50_Q28MR4 Cluster: Dehydrogenase E1 component; n=8; Bacter... 109 7e-23
UniRef50_Q0LRY7 Cluster: Dehydrogenase, E1 component:Transketola... 109 7e-23
UniRef50_Q0MX86 Cluster: Pyruvate dehydrogenase beta-subunit; n=... 108 9e-23
UniRef50_A0HHH4 Cluster: Transketolase, central region; n=2; Bac... 107 2e-22
UniRef50_P35488 Cluster: Pyruvate dehydrogenase E1 component sub... 107 2e-22
UniRef50_A0LFE7 Cluster: Transketolase domain protein; n=1; Synt... 107 2e-22
UniRef50_Q72GU2 Cluster: 2-oxoisovalerate dehydrogenase subunit ... 107 3e-22
UniRef50_A0H598 Cluster: Transketolase, central region; n=2; Chl... 104 1e-21
UniRef50_Q5BSL1 Cluster: SJCHGC03862 protein; n=1; Schistosoma j... 104 1e-21
UniRef50_A7BPK5 Cluster: Pyruvate dehydrogenase, E1 component, b... 103 3e-21
UniRef50_Q9Z9E8 Cluster: (Pyruvate) Oxoisovalerate Dehydrogenase... 102 6e-21
UniRef50_Q9KG98 Cluster: Pyruvate dehydrogenase E1 (Lipoamide) b... 101 2e-20
UniRef50_A5UVZ0 Cluster: Transketolase, central region; n=5; Bac... 100 2e-20
UniRef50_Q5UWH0 Cluster: Pyruvate dehydrogenase; n=55; cellular ... 99 4e-20
UniRef50_O34591 Cluster: Acetoin:2,6-dichlorophenolindophenol ox... 99 4e-20
UniRef50_Q4DEQ0 Cluster: 2-oxoisovalerate dehydrogenase beta sub... 100 5e-20
UniRef50_A0JY24 Cluster: Transketolase, central region; n=2; cel... 98 1e-19
UniRef50_A5ACP6 Cluster: Putative uncharacterized protein; n=1; ... 98 1e-19
UniRef50_Q0W152 Cluster: Pyruvate dehydrogenase complex E1, tran... 97 4e-19
UniRef50_Q9I1M1 Cluster: 2-oxoisovalerate dehydrogenase subunit ... 97 4e-19
UniRef50_Q479Q1 Cluster: Transketolase, central region:Transketo... 95 9e-19
UniRef50_P0A0A3 Cluster: Pyruvate dehydrogenase E1 component sub... 93 5e-18
UniRef50_P75391 Cluster: Pyruvate dehydrogenase E1 component sub... 93 5e-18
UniRef50_A1RJV5 Cluster: Transketolase, central region; n=18; ce... 91 2e-17
UniRef50_Q2BFQ9 Cluster: Putative uncharacterized protein; n=1; ... 90 3e-17
UniRef50_Q1ARM1 Cluster: Transketolase-like protein; n=2; Bacter... 90 3e-17
UniRef50_A7CXF2 Cluster: Transketolase central region; n=1; Opit... 89 6e-17
UniRef50_Q6ABX8 Cluster: Pyruvate dehydrogenase E1 component sub... 89 8e-17
UniRef50_P21882 Cluster: Pyruvate dehydrogenase E1 component sub... 88 2e-16
UniRef50_Q023C4 Cluster: Pyruvate dehydrogenase; n=1; Solibacter... 87 2e-16
UniRef50_A5V556 Cluster: Transketolase domain protein; n=1; Sphi... 86 5e-16
UniRef50_Q7N3C2 Cluster: Similar to 3-methyl-2-oxobutanoate dehy... 85 1e-15
UniRef50_Q319T3 Cluster: Pyruvate dehydrogenase; n=1; Prochloroc... 85 1e-15
UniRef50_Q83DL8 Cluster: Dehydrogenase, E1 component, beta subun... 85 2e-15
UniRef50_Q83X27 Cluster: Probable pyruvate dehydrogenase beta-su... 85 2e-15
UniRef50_A0M1U4 Cluster: 2-oxoisovalerate dehydrogenase E1 compo... 85 2e-15
UniRef50_Q020J5 Cluster: Dehydrogenase, E1 component; n=1; Solib... 83 5e-15
UniRef50_A1G854 Cluster: Transketolase, central region; n=3; Act... 82 9e-15
UniRef50_P21953 Cluster: 2-oxoisovalerate dehydrogenase subunit ... 82 9e-15
UniRef50_A4XHV5 Cluster: Transketolase, central region; n=3; Bac... 81 2e-14
UniRef50_A4XF90 Cluster: Transketolase domain protein; n=1; Novo... 81 2e-14
UniRef50_A4L2Q6 Cluster: E1 component beta subunit; n=16; Bacill... 81 2e-14
UniRef50_A7EW39 Cluster: Pyruvate dehydrogenase E1 component bet... 80 4e-14
UniRef50_Q1IQR3 Cluster: Dehydrogenase, E1 component; n=1; Acido... 77 3e-13
UniRef50_A3SJ75 Cluster: 2-oxoisovalerate dehydrogenase beta sub... 76 6e-13
UniRef50_Q2WB98 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 75 2e-12
UniRef50_Q9K3H1 Cluster: Putative pyruvate dehydrogenase beta su... 71 2e-11
UniRef50_Q8YDW3 Cluster: 2-OXOISOVALERATE DEHYDROGENASE BETA SUB... 70 4e-11
UniRef50_A2TU24 Cluster: (Pyruvate) Oxoisovalerate Dehydrogenase... 69 9e-11
UniRef50_Q00TN9 Cluster: Pyruvate dehydrogenase E1 component bet... 67 3e-10
UniRef50_Q8YDG0 Cluster: 2-OXOISOVALERATE DEHYDROGENASE BETA SUB... 66 8e-10
UniRef50_Q7N5R1 Cluster: Similar to 3-methyl-2-oxobutanoate dehy... 65 1e-09
UniRef50_UPI000038D520 Cluster: COG0022: Pyruvate/2-oxoglutarate... 64 2e-09
UniRef50_Q748I3 Cluster: Dehydrogenase, E1 component, alpha and ... 64 2e-09
UniRef50_A3BGZ8 Cluster: Putative uncharacterized protein; n=2; ... 64 3e-09
UniRef50_A3PXW7 Cluster: Transketolase domain protein; n=4; Myco... 60 5e-08
UniRef50_A6FZ18 Cluster: 2-oxoisovalerate dehydrogenase, E1 comp... 59 9e-08
UniRef50_A6W004 Cluster: Transketolase domain protein; n=6; Prot... 57 3e-07
UniRef50_A4F1Y5 Cluster: Branched-chain alpha-keto acid decarbox... 57 4e-07
UniRef50_A1GCL6 Cluster: Transketolase-like; n=2; Salinispora|Re... 57 4e-07
UniRef50_Q7NLM8 Cluster: Gll1094 protein; n=1; Gloeobacter viola... 56 5e-07
UniRef50_Q7V0M6 Cluster: Dehydrogenase E1 component beta subunit... 55 2e-06
UniRef50_A4BZ87 Cluster: Acetoin dehydrogenase (TPP-dependent) b... 52 1e-05
UniRef50_Q5LVW0 Cluster: Dehydrogenase/transketolase family prot... 49 8e-05
UniRef50_Q11G19 Cluster: Transketolase-like; n=2; Proteobacteria... 48 2e-04
UniRef50_A2C5U9 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 48 2e-04
UniRef50_Q50851 Cluster: Branched-chain keto acid dehydrogenase ... 46 5e-04
UniRef50_UPI0000D9ADA1 Cluster: PREDICTED: similar to 2-oxoisova... 46 7e-04
UniRef50_Q5AT21 Cluster: Putative uncharacterized protein; n=1; ... 41 0.020
UniRef50_UPI0000383A75 Cluster: COG0508: Pyruvate/2-oxoglutarate... 38 0.14
UniRef50_UPI00015970BB Cluster: GabT1; n=1; Bacillus amyloliquef... 36 0.75
UniRef50_Q2IY37 Cluster: Tyrosinase; n=1; Rhodopseudomonas palus... 34 2.3
UniRef50_A6LE04 Cluster: Putative uncharacterized protein; n=2; ... 34 2.3
UniRef50_Q8EVJ3 Cluster: Transposase for IS1202-like insertion s... 34 3.0
UniRef50_Q2IQQ3 Cluster: Putative uncharacterized protein precur... 34 3.0
UniRef50_Q4SZE5 Cluster: Chromosome undetermined SCAF11680, whol... 33 4.0
UniRef50_A6GB58 Cluster: Transketolase; n=1; Plesiocystis pacifi... 33 4.0
UniRef50_Q89XT5 Cluster: Glyoxalase II; n=16; Alphaproteobacteri... 33 5.3
UniRef50_A7SMP5 Cluster: Predicted protein; n=1; Nematostella ve... 33 5.3
UniRef50_A7AWY3 Cluster: Putative uncharacterized protein; n=1; ... 33 5.3
UniRef50_UPI0000DB7401 Cluster: PREDICTED: similar to zinc finge... 33 7.0
UniRef50_Q0RU52 Cluster: Putative uncharacterized protein; n=1; ... 33 7.0
UniRef50_A0YMZ8 Cluster: Hemolysin-type calcium-binding region p... 33 7.0
UniRef50_O74657 Cluster: Agglutinin-like protein 2 precursor; n=... 32 9.3
>UniRef50_P11177 Cluster: Pyruvate dehydrogenase E1 component
subunit beta, mitochondrial precursor; n=144; cellular
organisms|Rep: Pyruvate dehydrogenase E1 component
subunit beta, mitochondrial precursor - Homo sapiens
(Human)
Length = 359
Score = 247 bits (605), Expect = 1e-64
Identities = 111/152 (73%), Positives = 126/152 (82%)
Frame = +1
Query: 151 ALASKPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTP 330
A A+ VTVRDA+NQ +DEE+ERDEKVF+LGEEVAQYDGAYKV+RGLWKKYGDKR+IDTP
Sbjct: 27 APAALQVTVRDAINQGMDEELERDEKVFLLGEEVAQYDGAYKVSRGLWKKYGDKRIIDTP 86
Query: 331 ITEXXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRG 510
I+E L+PICEFMTFNFSMQAID +INSAAKT+YMS G PVPIVFRG
Sbjct: 87 ISEMGFAGIAVGAAMAGLRPICEFMTFNFSMQAIDQVINSAAKTYYMSGGLQPVPIVFRG 146
Query: 511 PNGAASSVAAQHSQCFGAWYSHCPGLKVLMPY 606
PNGA++ VAAQHSQCF AWY HCPGLKV+ P+
Sbjct: 147 PNGASAGVAAQHSQCFAAWYGHCPGLKVVSPW 178
>UniRef50_Q4UKQ7 Cluster: Pyruvate dehydrogenase E1 component
subunit beta; n=35; cellular organisms|Rep: Pyruvate
dehydrogenase E1 component subunit beta - Rickettsia
felis (Rickettsia azadi)
Length = 326
Score = 202 bits (493), Expect = 5e-51
Identities = 96/146 (65%), Positives = 111/146 (76%)
Frame = +1
Query: 169 VTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXX 348
+TVR+AL A+ EEM RD+KVFV+GEEVA+Y GAYKVT+GL +++G KRVIDTPITE
Sbjct: 3 ITVREALRDAMQEEMIRDDKVFVMGEEVAEYQGAYKVTQGLLEQFGPKRVIDTPITEYGF 62
Query: 349 XXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAAS 528
L+PI EFMTFNF+MQA DHI+NSAAKT YMS G PIVFRGPNGAAS
Sbjct: 63 AGLAVGAAFAGLRPIVEFMTFNFAMQAFDHIVNSAAKTHYMSGGQAKCPIVFRGPNGAAS 122
Query: 529 SVAAQHSQCFGAWYSHCPGLKVLMPY 606
VAAQHSQ + A YSH PGLKV+ PY
Sbjct: 123 RVAAQHSQNYTACYSHVPGLKVVAPY 148
>UniRef50_Q6N5V4 Cluster: Pyruvate dehydrogenase E1 beta subunit;
n=24; cellular organisms|Rep: Pyruvate dehydrogenase E1
beta subunit - Rhodopseudomonas palustris
Length = 469
Score = 198 bits (484), Expect = 6e-50
Identities = 95/146 (65%), Positives = 110/146 (75%)
Frame = +1
Query: 169 VTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXX 348
VT+R+AL A+ EEM RD VFV+GEEVA+Y GAYKVT+GL +++GD+RVIDTPITE
Sbjct: 147 VTIREALRDAMAEEMRRDPDVFVMGEEVAEYQGAYKVTQGLLQEFGDRRVIDTPITEHGF 206
Query: 349 XXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAAS 528
LKPI EFMTFNF+MQAID IINSAAKT YMS G + IVFRGPNGAAS
Sbjct: 207 AGVGVGAGFAGLKPIVEFMTFNFAMQAIDQIINSAAKTLYMSGGQLGCSIVFRGPNGAAS 266
Query: 529 SVAAQHSQCFGAWYSHCPGLKVLMPY 606
VAAQHSQ + AWY+ PGLKV+ PY
Sbjct: 267 RVAAQHSQDYSAWYAQIPGLKVVAPY 292
>UniRef50_O66113 Cluster: Pyruvate dehydrogenase E1 component
subunit beta; n=99; Bacteria|Rep: Pyruvate dehydrogenase
E1 component subunit beta - Zymomonas mobilis
Length = 462
Score = 192 bits (468), Expect = 6e-48
Identities = 90/145 (62%), Positives = 108/145 (74%)
Frame = +1
Query: 172 TVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXX 351
T+R+AL A+ EEM RD++VFV+GEEVA+Y GAYKVT+GL +++G +RV+DTPI+E
Sbjct: 140 TLREALRDAMAEEMRRDDRVFVMGEEVAEYQGAYKVTQGLLQEFGARRVVDTPISEYGFS 199
Query: 352 XXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASS 531
L+P+ EFMT NFSMQAIDHIINSAAKT YMS G V PIVFRGPNGAA
Sbjct: 200 GIGVGAAMEGLRPVIEFMTMNFSMQAIDHIINSAAKTHYMSGGQVRCPIVFRGPNGAAPR 259
Query: 532 VAAQHSQCFGAWYSHCPGLKVLMPY 606
V AQH+Q FG WY+ PGL VL PY
Sbjct: 260 VGAQHTQNFGPWYAAVPGLVVLAPY 284
>UniRef50_Q1VWM3 Cluster: Pyruvate dehydrogenase E1 component, beta
subunit; n=1; Psychroflexus torquis ATCC 700755|Rep:
Pyruvate dehydrogenase E1 component, beta subunit -
Psychroflexus torquis ATCC 700755
Length = 325
Score = 160 bits (388), Expect = 3e-38
Identities = 71/147 (48%), Positives = 102/147 (69%)
Frame = +1
Query: 163 KPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEX 342
+ + R+A+ +A+ EEM DE ++++GEEVA+Y+GAYK ++G+ ++G+KRVIDTPI+E
Sbjct: 2 RTIQFREAIVEAMSEEMRADETIYLMGEEVAEYNGAYKASKGMLDEFGEKRVIDTPISEL 61
Query: 343 XXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGA 522
+PI EFMTFNFS+ ID IIN+AAK MS G +PIVFRGP G+
Sbjct: 62 GFTGIGIGSAMNGNRPIIEFMTFNFSLVGIDQIINNAAKMRQMSGGQFNIPIVFRGPTGS 121
Query: 523 ASSVAAQHSQCFGAWYSHCPGLKVLMP 603
A + A HSQ F +W+++ PGLKV++P
Sbjct: 122 AGQLGATHSQAFESWFANTPGLKVVIP 148
>UniRef50_Q8IML6 Cluster: CG11876-PB, isoform B; n=2; melanogaster
subgroup|Rep: CG11876-PB, isoform B - Drosophila
melanogaster (Fruit fly)
Length = 273
Score = 158 bits (384), Expect = 8e-38
Identities = 79/127 (62%), Positives = 96/127 (75%), Gaps = 2/127 (1%)
Frame = +1
Query: 124 SRRSFATS-KALASKPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKK 300
++R+F+TS KALA+K +TVRDALN A+D+E+ RD++VF+LGEEVAQYDGAYKV+RGLWKK
Sbjct: 13 AQRAFSTSQKALAAKQMTVRDALNSALDDELARDDRVFILGEEVAQYDGAYKVSRGLWKK 72
Query: 301 YGDKRVIDTPITEXXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHI-INSAAKTFYMSA 477
YGDKRVIDTPITE L+P+CEFMT+NFSMQAIDH I AK
Sbjct: 73 YGDKRVIDTPITEMGFAGIAVGAAMAGLRPVCEFMTWNFSMQAIDHAKILDCAKP---PV 129
Query: 478 GTVPVPI 498
G P+PI
Sbjct: 130 GDRPLPI 136
>UniRef50_A6Q3I5 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
complex, E1 component, beta subunit; n=1; Nitratiruptor
sp. SB155-2|Rep: Pyruvate/2-oxoglutarate dehydrogenase
complex, E1 component, beta subunit - Nitratiruptor sp.
(strain SB155-2)
Length = 325
Score = 145 bits (352), Expect = 6e-34
Identities = 69/140 (49%), Positives = 91/140 (65%)
Frame = +1
Query: 178 RDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXX 357
R+ALN+AIDE M+ DE V +LGE+V +Y G+Y+V+ GL+ KYG KRVIDTPI E
Sbjct: 4 REALNRAIDESMKADESVVILGEDVGRYGGSYRVSEGLFAKYGPKRVIDTPIAELSIVGN 63
Query: 358 XXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASSVA 537
L+PI E MT NFS+ A+D I+N AAK YMS G + +P+ R P G + +A
Sbjct: 64 AIGMAIGGLRPIAEIMTVNFSLLAMDQIVNHAAKFRYMSGGKMTIPLTIRIPGGVSRQLA 123
Query: 538 AQHSQCFGAWYSHCPGLKVL 597
AQHS+ + Y+ PGL VL
Sbjct: 124 AQHSESYETLYASIPGLIVL 143
>UniRef50_Q74AE0 Cluster: Dehydrogenase complex, E1 component, beta
subunit; n=7; Bacteria|Rep: Dehydrogenase complex, E1
component, beta subunit - Geobacter sulfurreducens
Length = 328
Score = 139 bits (336), Expect = 5e-32
Identities = 65/142 (45%), Positives = 88/142 (61%)
Frame = +1
Query: 178 RDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXX 357
RDALN A+ EEM RD V V GE+VA Y+G++KVTRGL ++G++RV DTPI+E
Sbjct: 7 RDALNLALKEEMRRDPSVVVWGEDVALYEGSFKVTRGLLAEFGEERVKDTPISENSIVGV 66
Query: 358 XXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASSVA 537
L+P+ E MT NF++ A+D I+N AK M G +P+V R P G S +
Sbjct: 67 AVGAAMGGLRPVAELMTVNFALLAMDQIVNHMAKIRSMFGGQTYLPMVVRAPGGGGSQLG 126
Query: 538 AQHSQCFGAWYSHCPGLKVLMP 603
AQHSQ ++ HCPG+ V +P
Sbjct: 127 AQHSQSLETYFMHCPGIHVAVP 148
>UniRef50_Q8DMB7 Cluster: Pyruvate dehydrogenase E1 component beta
subunit; n=6; cellular organisms|Rep: Pyruvate
dehydrogenase E1 component beta subunit - Synechococcus
elongatus (Thermosynechococcus elongatus)
Length = 327
Score = 134 bits (324), Expect = 2e-30
Identities = 64/139 (46%), Positives = 83/139 (59%)
Frame = +1
Query: 181 DALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXXX 360
+AL AIDEEMERD VFVLGE+V Y G+YKVT+ L+KKYG+ R++DTPI E
Sbjct: 8 NALRAAIDEEMERDPTVFVLGEDVGHYGGSYKVTKDLYKKYGELRLLDTPIAENSFTGMA 67
Query: 361 XXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASSVAA 540
L+PI E M F + A + I N+A Y S G +PIV RGP G + A
Sbjct: 68 IGAAMTGLRPIVEGMNMGFLLLAFNQIANNAGMLRYTSGGNFKIPIVIRGPGGVGRQLGA 127
Query: 541 QHSQCFGAWYSHCPGLKVL 597
+HSQ A++ PGLK++
Sbjct: 128 EHSQRLEAYFQAVPGLKIV 146
>UniRef50_A7CXZ3 Cluster: Transketolase central region; n=1;
Opitutaceae bacterium TAV2|Rep: Transketolase central
region - Opitutaceae bacterium TAV2
Length = 327
Score = 130 bits (315), Expect = 2e-29
Identities = 63/145 (43%), Positives = 90/145 (62%)
Frame = +1
Query: 169 VTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXX 348
+T R+A+ A+ EE+ERDE V VLGEEV Q+ GAYKV+ GL +K+G KR++DTPI+E
Sbjct: 4 LTYREAVRAALAEELERDENVVVLGEEVGQFHGAYKVSEGLLEKFGPKRIVDTPISEAGF 63
Query: 349 XXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAAS 528
++P+ E M ++F A D I+N+AA YMS G + PIV RGP +
Sbjct: 64 IGLGVGASMLGIRPVMELMFWSFYSVAFDQILNNAANIRYMSGGQINCPIVIRGPANGGT 123
Query: 529 SVAAQHSQCFGAWYSHCPGLKVLMP 603
+V A HS ++ PG+KV++P
Sbjct: 124 NVGATHSHTPENVLANHPGVKVVVP 148
>UniRef50_Q98FT4 Cluster: Acetoin dehydrogenase (TPP-dependent) beta
chain; n=25; Bacteria|Rep: Acetoin dehydrogenase
(TPP-dependent) beta chain - Rhizobium loti
(Mesorhizobium loti)
Length = 332
Score = 130 bits (313), Expect = 3e-29
Identities = 60/147 (40%), Positives = 90/147 (61%)
Frame = +1
Query: 163 KPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEX 342
+ ++ A+ +A+ M+ DE+VF++GE++ Y GA++VT L ++YG +RVIDTPI+E
Sbjct: 6 RELSYAQAIQEAMAIAMDMDERVFLMGEDIGVYGGAFQVTGDLVERYGTERVIDTPISEL 65
Query: 343 XXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGA 522
++PI EF +F+ A++ I+N AAK +M G V VP+V R P G+
Sbjct: 66 GGAGVAVGAALTGMRPIFEFQFSDFATLAMEQIVNQAAKMRFMLGGEVSVPVVMRFPAGS 125
Query: 523 ASSVAAQHSQCFGAWYSHCPGLKVLMP 603
+ AAQHSQ AW H PGLKV+ P
Sbjct: 126 GTGAAAQHSQSLEAWLGHVPGLKVIQP 152
>UniRef50_A6UDY4 Cluster: Transketolase central region; n=1;
Sinorhizobium medicae WSM419|Rep: Transketolase central
region - Sinorhizobium medicae WSM419
Length = 325
Score = 128 bits (309), Expect = 1e-28
Identities = 62/145 (42%), Positives = 82/145 (56%)
Frame = +1
Query: 169 VTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXX 348
+T RDAL +A+D+ M D + V+GEEV +Y GAY VT+ L K +G R+IDTPI+E
Sbjct: 5 MTYRDALRKALDDAMTDDSSIVVIGEEVGRYGGAYGVTKDLIKIHGADRLIDTPISEPAI 64
Query: 349 XXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAAS 528
L+P+ E M +F +D + N AAK YM G + VP+V R G
Sbjct: 65 VGTAVGAAMTGLRPVAELMYIDFLGMTMDQLANQAAKIRYMFGGQIGVPMVLRTQGGTGR 124
Query: 529 SVAAQHSQCFGAWYSHCPGLKVLMP 603
S AQHSQ AW H PGL++ MP
Sbjct: 125 SAGAQHSQSLEAWVMHTPGLRLAMP 149
>UniRef50_Q32RM2 Cluster: Pyruvate dehydrogenase E1 component
subunit beta; n=66; cellular organisms|Rep: Pyruvate
dehydrogenase E1 component subunit beta - Zygnema
circumcarinatum (Green alga)
Length = 325
Score = 124 bits (300), Expect = 1e-27
Identities = 56/143 (39%), Positives = 83/143 (58%)
Frame = +1
Query: 169 VTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXX 348
V + +AL Q + EEM+RD +V V+GE+V Y G+YKVT+G ++YGD R++DTPI E
Sbjct: 4 VLLFEALRQGLQEEMDRDPRVMVMGEDVGHYGGSYKVTKGFAERYGDLRLLDTPIAENSF 63
Query: 349 XXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAAS 528
L+P+ E M F + A + I N+A Y S G +PIV RGP G
Sbjct: 64 TGMAIGAAMTGLRPVVEGMNMGFLLLAFNQIANNAGMLHYTSGGNFTIPIVIRGPGGVGR 123
Query: 529 SVAAQHSQCFGAWYSHCPGLKVL 597
+ A+HSQ +++ PGL+++
Sbjct: 124 QLGAEHSQRLESYFQSVPGLQMV 146
>UniRef50_A5UU14 Cluster: Transketolase, central region; n=3;
Chloroflexi (class)|Rep: Transketolase, central region -
Roseiflexus sp. RS-1
Length = 322
Score = 124 bits (299), Expect = 2e-27
Identities = 59/145 (40%), Positives = 88/145 (60%)
Frame = +1
Query: 169 VTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXX 348
+TVR+AL QA+ + M+ DE+VF++GE++ Y Y VT G ++YG +R+ D PI E
Sbjct: 4 ITVREALRQALHDAMQ-DERVFIIGEDIGHYGSTYGVTAGFLEQYGPERIRDAPIAESGI 62
Query: 349 XXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAAS 528
++PI E M+ NFS+ A D + N AAK + M G + VP+V R NG +
Sbjct: 63 VGIAIGAAMVGMRPIAEIMSVNFSLLAFDMLFNHAAKIYSMFGGQMTVPMVLRTTNG-WT 121
Query: 529 SVAAQHSQCFGAWYSHCPGLKVLMP 603
++A HSQ F +++H PGLKV+ P
Sbjct: 122 QLSATHSQSFDVYFAHMPGLKVVAP 146
>UniRef50_A3VIE8 Cluster: Acetoin dehydrogenase (TPP-dependent) beta
chain; n=2; Rhodobacterales|Rep: Acetoin dehydrogenase
(TPP-dependent) beta chain - Rhodobacterales bacterium
HTCC2654
Length = 333
Score = 123 bits (297), Expect = 3e-27
Identities = 62/150 (41%), Positives = 87/150 (58%)
Frame = +1
Query: 154 LASKPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPI 333
+ + +T+ A+N+A+ EEM RDE VF+LGE+VA+ +KV GL +++G RVIDTPI
Sbjct: 1 MTMREITLSQAVNEALAEEMRRDETVFILGEDVAEAGTPFKVLSGLVEEFGTDRVIDTPI 60
Query: 334 TEXXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGP 513
+E +P+ + M +F +D + N AAK YMS G + VP+V R
Sbjct: 61 SEPGFVGLAVGAAMTGARPVVDLMFGDFLYLVMDQLCNQAAKQHYMSGGKLSVPMVLRTN 120
Query: 514 NGAASSVAAQHSQCFGAWYSHCPGLKVLMP 603
GA AAQHSQ A +H PGLKV +P
Sbjct: 121 LGATRRSAAQHSQSLQALVAHIPGLKVALP 150
>UniRef50_Q5L234 Cluster: Thiamine pyrophosphate-dependent
dehydrogenases, E1 component beta subunit; n=13;
cellular organisms|Rep: Thiamine pyrophosphate-dependent
dehydrogenases, E1 component beta subunit - Geobacillus
kaustophilus
Length = 339
Score = 120 bits (290), Expect = 2e-26
Identities = 63/145 (43%), Positives = 83/145 (57%)
Frame = +1
Query: 169 VTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXX 348
+T AL +AI EMERD VFV+GE+V Y G + T GL++K+G +RVIDTPI+E
Sbjct: 9 LTGNKALAEAIRLEMERDPNVFVMGEDVGVYGGIFGATEGLFQKFGPERVIDTPISETAF 68
Query: 349 XXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAAS 528
++PI E M +F +D I N AK YMS G V +P+V G
Sbjct: 69 IGAAIGAAAEGMRPIVELMFVDFFGVCMDQIYNHMAKIPYMSGGRVKLPMVLMTAVGGGY 128
Query: 529 SVAAQHSQCFGAWYSHCPGLKVLMP 603
S AAQHSQ A ++H PG+KV+ P
Sbjct: 129 SDAAQHSQTLYATFAHLPGMKVVAP 153
>UniRef50_Q03KN0 Cluster: Pyruvate dehydrogenase (E1) component,
beta subunit; n=24; Streptococcus|Rep: Pyruvate
dehydrogenase (E1) component, beta subunit -
Streptococcus thermophilus (strain ATCC BAA-491 / LMD-9)
Length = 337
Score = 120 bits (290), Expect = 2e-26
Identities = 55/148 (37%), Positives = 87/148 (58%)
Frame = +1
Query: 160 SKPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITE 339
+K + +R+A+N A+ EEM +D +F++GE+V Y G + + G+ ++G+KRV DTPI+E
Sbjct: 9 TKLMALREAVNLAMSEEMRKDPDIFLMGEDVGIYGGDFGTSVGMLAEFGEKRVKDTPISE 68
Query: 340 XXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNG 519
L+PI + +F A+D I+N+ AK YM G + P+ FR +G
Sbjct: 69 AAIAGAAVGAAITGLRPIVDLTFMDFITIALDAIVNNGAKNNYMFGGGLKTPVTFRVASG 128
Query: 520 AASSVAAQHSQCFGAWYSHCPGLKVLMP 603
+ AAQHSQ +W +H PG+KV+ P
Sbjct: 129 SGIGSAAQHSQSLESWLTHIPGIKVVAP 156
>UniRef50_A5V539 Cluster: Transketolase, central region; n=4;
Bacteria|Rep: Transketolase, central region -
Sphingomonas wittichii RW1
Length = 324
Score = 120 bits (290), Expect = 2e-26
Identities = 55/140 (39%), Positives = 79/140 (56%)
Frame = +1
Query: 184 ALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXXXX 363
A+N+A+D+ + D V +LGE++A G + VTRGL K+G RVID PI E
Sbjct: 9 AINRALDDALAADPSVLLLGEDIANAGGTFAVTRGLLDKHGPDRVIDMPIAENAIAGMAV 68
Query: 364 XXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASSVAAQ 543
+P+ E M +F +D ++N AAK +M G VP+V R +G + Q
Sbjct: 69 GLALGGFRPVVEIMFMDFMTLTMDALVNQAAKLHFMFGGQSAVPMVVRTQHGGGLNAGPQ 128
Query: 544 HSQCFGAWYSHCPGLKVLMP 603
HSQC AW++H PGLKV++P
Sbjct: 129 HSQCLEAWFAHIPGLKVVVP 148
>UniRef50_P37941 Cluster: 2-oxoisovalerate dehydrogenase subunit
beta; n=39; Bacteria|Rep: 2-oxoisovalerate dehydrogenase
subunit beta - Bacillus subtilis
Length = 327
Score = 120 bits (289), Expect = 3e-26
Identities = 59/141 (41%), Positives = 84/141 (59%)
Frame = +1
Query: 181 DALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXXX 360
DA+N A+ EEMERD +VFVLGE+V + G +K T GL++++G++RV+DTP+ E
Sbjct: 8 DAINLAMKEEMERDSRVFVLGEDVGRKGGVFKATAGLYEQFGEERVMDTPLAESAIAGVG 67
Query: 361 XXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASSVAA 540
++PI E +F M A++ II+ AAK Y S PIV R P G A
Sbjct: 68 IGAAMYGMRPIAEMQFADFIMPAVNQIISEAAKIRYRSNNDWSCPIVVRAPYGGGVHGAL 127
Query: 541 QHSQCFGAWYSHCPGLKVLMP 603
HSQ A +++ PGLK++MP
Sbjct: 128 YHSQSVEAIFANQPGLKIVMP 148
>UniRef50_Q3WCG4 Cluster: Transketolase, central
region:Transketolase, C terminal; n=7; Bacteria|Rep:
Transketolase, central region:Transketolase, C terminal
- Frankia sp. EAN1pec
Length = 351
Score = 118 bits (285), Expect = 8e-26
Identities = 59/145 (40%), Positives = 82/145 (56%)
Frame = +1
Query: 169 VTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXX 348
+T+R+ALN A+D+ + RDE+VF+LGE++A G+ T+GL KYG RV+DTPI+E
Sbjct: 21 MTMREALNLALDQALARDERVFLLGEDIAD-PGSSGPTKGLSTKYGADRVLDTPISEAAI 79
Query: 349 XXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAAS 528
+P+ E M +F A D I+N AAK +M+ G PI R
Sbjct: 80 VGAAIGAAMEGFRPVAEIMIMDFIGIAADQIVNHAAKLRFMTGGRTTAPITVRTQVYGGL 139
Query: 529 SVAAQHSQCFGAWYSHCPGLKVLMP 603
A HSQ AW+ H PGLKV++P
Sbjct: 140 GTGATHSQSLEAWFMHVPGLKVIVP 164
>UniRef50_P96103 Cluster: Pyruvate dehydrogenase complex E1 beta
subunit; n=3; Proteobacteria|Rep: Pyruvate dehydrogenase
complex E1 beta subunit - Thiobacillus ferrooxidans
(Acidithiobacillus ferrooxidans)
Length = 343
Score = 118 bits (283), Expect = 1e-25
Identities = 58/137 (42%), Positives = 78/137 (56%)
Frame = +1
Query: 193 QAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXXXXXXX 372
+A DEEM RD VF +GE++ G YK T GL+ KYG++RVIDTPI+E
Sbjct: 12 RAHDEEMARDPLVFAMGEDIGVAGGTYKATSGLFAKYGEQRVIDTPISENSYTGIGVGAA 71
Query: 373 XXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASSVAAQHSQ 552
+PI E M+ NF+ A+D ++N+AAK YMS G + P V R P G A + AQHS
Sbjct: 72 MIGARPIVEIMSVNFAWLAMDQLMNNAAKIHYMSGGRIRCPFVMRVPGGTAHQLGAQHSA 131
Query: 553 CFGAWYSHCPGLKVLMP 603
+ GL+V+ P
Sbjct: 132 RMEKVFMGISGLRVVTP 148
>UniRef50_UPI000155C0B5 Cluster: PREDICTED: similar to pyruvate
dehydrogenase (lipoamide) beta, partial; n=1;
Ornithorhynchus anatinus|Rep: PREDICTED: similar to
pyruvate dehydrogenase (lipoamide) beta, partial -
Ornithorhynchus anatinus
Length = 141
Score = 115 bits (277), Expect = 8e-25
Identities = 51/57 (89%), Positives = 57/57 (100%)
Frame = +1
Query: 169 VTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITE 339
VTVRDALNQA+DEE+ERDEKVF+LGEEVAQYDGAYKV+RGLWKKYGDKR+IDTPI+E
Sbjct: 1 VTVRDALNQALDEELERDEKVFLLGEEVAQYDGAYKVSRGLWKKYGDKRIIDTPISE 57
>UniRef50_A1SN85 Cluster: Transketolase, central region; n=4;
cellular organisms|Rep: Transketolase, central region -
Nocardioides sp. (strain BAA-499 / JS614)
Length = 347
Score = 115 bits (277), Expect = 8e-25
Identities = 60/148 (40%), Positives = 80/148 (54%)
Frame = +1
Query: 160 SKPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITE 339
S+ +T A+ +AI EMERD VF LGE+V Y G + T GL ++G RVIDTPI+E
Sbjct: 14 SRRLTTSKAIVEAIAFEMERDPSVFYLGEDVGSYGGIFGSTGGLLDRFGKDRVIDTPISE 73
Query: 340 XXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNG 519
++PI E M +F +D I N AK + S G V VP+V G
Sbjct: 74 TAFIGLGIGAAVEGMRPIVELMFADFMGVCLDQIYNHMAKIHFESGGNVKVPMVLTMAAG 133
Query: 520 AASSVAAQHSQCFGAWYSHCPGLKVLMP 603
S AQHSQC ++H PG+KV++P
Sbjct: 134 GGYSDGAQHSQCLWGTFAHLPGMKVVVP 161
>UniRef50_A0UXT4 Cluster: Transketolase-like; n=1; Clostridium
cellulolyticum H10|Rep: Transketolase-like - Clostridium
cellulolyticum H10
Length = 346
Score = 115 bits (276), Expect = 1e-24
Identities = 55/154 (35%), Positives = 83/154 (53%)
Frame = +1
Query: 142 TSKALASKPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVI 321
T + + ++ +DAL +A+D+ + RD +VF++GE V G + T+GL +KYG RV
Sbjct: 17 TDDSEIGRMISYKDALYEALDQSLARDPRVFIMGEGVDDPGGVFGTTKGLHEKYGRNRVF 76
Query: 322 DTPITEXXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIV 501
DTPI E L+PI +F + ++D ++N AAK YM+ G V VP+V
Sbjct: 77 DTPIAENSLTGIAAGAAMAGLRPIFVHSRMDFLLLSLDQLVNHAAKWSYMTGGKVKVPLV 136
Query: 502 FRGPNGAASSVAAQHSQCFGAWYSHCPGLKVLMP 603
R + AQHSQC + PGLK+ +P
Sbjct: 137 VRTVSARGWGSGAQHSQCLHGMLMNAPGLKIAVP 170
>UniRef50_A5V352 Cluster: Transketolase, central region; n=1;
Sphingomonas wittichii RW1|Rep: Transketolase, central
region - Sphingomonas wittichii RW1
Length = 334
Score = 114 bits (275), Expect = 1e-24
Identities = 61/157 (38%), Positives = 81/157 (51%), Gaps = 2/157 (1%)
Frame = +1
Query: 139 ATSKALASKPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYD--GAYKVTRGLWKKYGDK 312
AT A + A+N AI + ME D+ V VLGE+VA + G VT+GL ++GD
Sbjct: 2 ATQTAAKPAKANILQAINAAIADAMEADDNVVVLGEDVADPEEGGVCGVTKGLSSRFGDA 61
Query: 313 RVIDTPITEXXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPV 492
RV TPI+E KP+ E M NF+ A+D I+N AAK +MS G V
Sbjct: 62 RVRSTPISEQAIVGAAIGASLVGFKPVAEIMLMNFTTVAMDMIVNHAAKLRFMSGGQTHV 121
Query: 493 PIVFRGPNGAASSVAAQHSQCFGAWYSHCPGLKVLMP 603
PIV R G + QH AW++H G+KV+ P
Sbjct: 122 PIVIRTMTGTGFASGGQHCDYLEAWFAHTAGIKVVAP 158
>UniRef50_Q1AZ53 Cluster: Transketolase, central region; n=1;
Rubrobacter xylanophilus DSM 9941|Rep: Transketolase,
central region - Rubrobacter xylanophilus (strain DSM
9941 / NBRC 16129)
Length = 330
Score = 112 bits (270), Expect = 5e-24
Identities = 57/145 (39%), Positives = 77/145 (53%)
Frame = +1
Query: 169 VTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXX 348
++ +AL +A+DEE+ RDE+ F +GE+V + G + GL +KYG +RV DTPI+E
Sbjct: 5 ISYTEALREALDEELGRDERTFFMGEDVGAFGGIFGEAAGLQQKYGKERVFDTPISETFI 64
Query: 349 XXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAAS 528
L+PI E +F A+D I N AAK YM G VP+V P GA
Sbjct: 65 VGGGVGAAITGLRPIVELQFADFVSVAMDEIYNKAAKWRYMHGGLFKVPLVIIAPEGAMG 124
Query: 529 SVAAQHSQCFGAWYSHCPGLKVLMP 603
+HSQC A + GL VL P
Sbjct: 125 GAGPEHSQCPEALFWSAAGLYVLTP 149
>UniRef50_Q5HKL9 Cluster: Acetoin dehydrogenase, E1 component, beta
subunit; n=4; Bacilli|Rep: Acetoin dehydrogenase, E1
component, beta subunit - Staphylococcus epidermidis
(strain ATCC 35984 / RP62A)
Length = 346
Score = 111 bits (268), Expect = 9e-24
Identities = 61/159 (38%), Positives = 87/159 (54%), Gaps = 12/159 (7%)
Frame = +1
Query: 163 KPVTVRDALNQAIDEEMERDEKVFVLGEEVA------------QYDGAYKVTRGLWKKYG 306
+ +T A+N+AID+ ME+DE V ++G +V+ + G + VT+GL KKY
Sbjct: 5 RKLTFMGAINEAIDQSMEKDEDVILIGTDVSGGAKVDHIKDDDTFGGVFGVTKGLAKKYS 64
Query: 307 DKRVIDTPITEXXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTV 486
KRVIDTPI E L+PI E M +F +D I+N AK YM G
Sbjct: 65 RKRVIDTPIAEHITLSTAVGAAATGLRPIAELMFNDFIGFGLDPILNQGAKMRYMFGGKA 124
Query: 487 PVPIVFRGPNGAASSVAAQHSQCFGAWYSHCPGLKVLMP 603
+P+V R +GA +S AAQHSQ ++ PG+KV++P
Sbjct: 125 KIPLVVRTVHGAGASAAAQHSQSLYNMFAAIPGVKVVVP 163
>UniRef50_Q5VGY3 Cluster: Pyruvate dehydrogenase beta subunit; n=2;
Plasmodium falciparum|Rep: Pyruvate dehydrogenase beta
subunit - Plasmodium falciparum
Length = 415
Score = 110 bits (265), Expect = 2e-23
Identities = 55/141 (39%), Positives = 80/141 (56%)
Frame = +1
Query: 175 VRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXXX 354
+ +AL+ AI EEM++D+ V+VLGE+V Y G+YKVT+ L +G RV+DTPI E
Sbjct: 94 ISEALHMAIYEEMKKDKGVYVLGEDVGLYGGSYKVTKNLAHFFGFSRVLDTPICENAFMG 153
Query: 355 XXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASSV 534
L+PI E M +F + A + I N+A YM G +PIV RGP G +
Sbjct: 154 LGIGSAINDLRPIIEGMNLSFLILAFNQISNNACMMRYMCDGQFNIPIVIRGPGGIGKQL 213
Query: 535 AAQHSQCFGAWYSHCPGLKVL 597
+HSQ ++ PG+K++
Sbjct: 214 GPEHSQRIESYLMSIPGIKIV 234
>UniRef50_A0Z5N8 Cluster: Acetoin dehydrogenase E1 component, beta
subunit; n=1; marine gamma proteobacterium HTCC2080|Rep:
Acetoin dehydrogenase E1 component, beta subunit -
marine gamma proteobacterium HTCC2080
Length = 325
Score = 110 bits (264), Expect = 3e-23
Identities = 57/146 (39%), Positives = 78/146 (53%), Gaps = 1/146 (0%)
Frame = +1
Query: 169 VTVRDALNQAIDEEMERDEKVFVLGEEVAQ-YDGAYKVTRGLWKKYGDKRVIDTPITEXX 345
++VR+A+N + EEM RD +V ++GE+VA G Y VT GL +K+G RVIDTPITE
Sbjct: 3 MSVREAINLTLHEEMARDPRVVIMGEDVASGQGGVYGVTAGLTEKFGVARVIDTPITESA 62
Query: 346 XXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAA 525
L+P+ E M +F +D ++N AK YM G P+V R GA
Sbjct: 63 IVGAAGGAALTGLRPVAELMFIDFLGVCLDQLLNQIAKFRYMFGGQARTPLVIRTMIGAG 122
Query: 526 SSVAAQHSQCFGAWYSHCPGLKVLMP 603
QHSQ + PG+KV+ P
Sbjct: 123 EGTGPQHSQILYPMLAAIPGIKVVAP 148
>UniRef50_A0LTR0 Cluster: Transketolase, central region; n=2;
Actinobacteria (class)|Rep: Transketolase, central
region - Acidothermus cellulolyticus (strain ATCC 43068
/ 11B)
Length = 327
Score = 109 bits (262), Expect = 5e-23
Identities = 54/145 (37%), Positives = 77/145 (53%)
Frame = +1
Query: 169 VTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXX 348
++ R+A+ + + +EM RD +V ++GE+V G +K T GL ++G RVIDTPI E
Sbjct: 4 LSYREAVARGLAQEMARDSRVVLIGEDVGAAGGVFKATVGLLDQFGPSRVIDTPIAEQAI 63
Query: 349 XXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAAS 528
++P+ E M +F D I N AKT YM+ G + +P+V R NG
Sbjct: 64 IGAAMGAAMNGMRPVAEIMFSDFFAVCWDQIANQIAKTRYMTHGQISLPLVIRTANGGGV 123
Query: 529 SVAAQHSQCFGAWYSHCPGLKVLMP 603
AQHSQ W PGLKV+ P
Sbjct: 124 RFGAQHSQSVENWAMMVPGLKVVAP 148
>UniRef50_Q97YF5 Cluster: Pyruvate dehydrogenase, beta subunit
(Lipoamide); n=1; Sulfolobus solfataricus|Rep: Pyruvate
dehydrogenase, beta subunit (Lipoamide) - Sulfolobus
solfataricus
Length = 332
Score = 109 bits (262), Expect = 5e-23
Identities = 52/143 (36%), Positives = 77/143 (53%)
Frame = +1
Query: 175 VRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXXX 354
+ A+ + I +EMER++++ VLGE+V + + T GL+ K+G KRVIDTPITE
Sbjct: 6 IAQAIAEGIRQEMERNDRIVVLGEDVTYWGAVFGFTMGLFDKFGRKRVIDTPITEQTFMG 65
Query: 355 XXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASSV 534
L P+ M +F D + N AK +YMS G P+PI G
Sbjct: 66 ISVGAASSGLHPVVSLMFVDFLGAGFDQMFNHMAKNYYMSGGQYPMPITVITAIGGGYGD 125
Query: 535 AAQHSQCFGAWYSHCPGLKVLMP 603
++QHSQ + ++H PG KV++P
Sbjct: 126 SSQHSQVLYSLFAHLPGFKVIVP 148
>UniRef50_Q28MR4 Cluster: Dehydrogenase E1 component; n=8;
Bacteria|Rep: Dehydrogenase E1 component - Jannaschia
sp. (strain CCS1)
Length = 675
Score = 109 bits (261), Expect = 7e-23
Identities = 53/157 (33%), Positives = 84/157 (53%)
Frame = +1
Query: 133 SFATSKALASKPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDK 312
++ A S+ +T A+ +A ++M RD + +LGE+V + G + +T+GL+ +G
Sbjct: 340 AYPAPPAAGSRKITYAQAITEAFAQQMARDPDLLILGEDVGRTGGIFGLTKGLFDTFGPD 399
Query: 313 RVIDTPITEXXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPV 492
RV DTPI+E + + E ++F +D I+N AAK +M G V
Sbjct: 400 RVRDTPISEGAIATCGVGAAMRGKRVVVEAQLWDFVTLMMDAIVNQAAKARFMLGGKAKV 459
Query: 493 PIVFRGPNGAASSVAAQHSQCFGAWYSHCPGLKVLMP 603
PIVFRGP GA +AAQH Q +++ PGL++ P
Sbjct: 460 PIVFRGPQGAGIRLAAQHCQSLEMLFANVPGLEIYAP 496
>UniRef50_Q0LRY7 Cluster: Dehydrogenase, E1 component:Transketolase,
central region:Transketolase-like; n=3; cellular
organisms|Rep: Dehydrogenase, E1
component:Transketolase, central
region:Transketolase-like - Caulobacter sp. K31
Length = 680
Score = 109 bits (261), Expect = 7e-23
Identities = 60/181 (33%), Positives = 93/181 (51%), Gaps = 2/181 (1%)
Frame = +1
Query: 64 IIFKMALKSSPAVLGMLTRLSRRSFATSKALA--SKPVTVRDALNQAIDEEMERDEKVFV 237
++ ++ +P+ L + ++ KA A S+ ++ +A+N A+ E+E DE+ +
Sbjct: 311 LVLRVMASPAPSPADALQPIHGQTTEDRKARAPESRSMSYVEAVNAALRAELEEDERTVL 370
Query: 238 LGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXXXXXXXXXXLKPICEFMTFNF 417
GE+V + G + +R L + +G RV DTPI E LKPI E M +F
Sbjct: 371 YGEDVGKSGGIFAASRYLQRDFGADRVFDTPIAENAILGSAVGAALGGLKPIVEIMWADF 430
Query: 418 SMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASSVAAQHSQCFGAWYSHCPGLKVL 597
A+D ++N AA Y++AG VP+V R GA AQHSQ A +H PGLKV
Sbjct: 431 IFVALDQLVNQAANVRYITAGKSSVPLVVRTQQGATPGSCAQHSQSIEAILAHVPGLKVA 490
Query: 598 M 600
+
Sbjct: 491 L 491
>UniRef50_Q0MX86 Cluster: Pyruvate dehydrogenase beta-subunit; n=3;
Bacteria|Rep: Pyruvate dehydrogenase beta-subunit -
consortium cosmid clone pGZ1
Length = 333
Score = 108 bits (260), Expect = 9e-23
Identities = 58/145 (40%), Positives = 79/145 (54%)
Frame = +1
Query: 169 VTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXX 348
+T A ++ M D V LGE++ + G + RGL + +G +RVIDTPI+E
Sbjct: 9 MTYSAAAAASLAAAMHADSSVVALGEDLGR-GGIFGQYRGLLEAFGPERVIDTPISEATI 67
Query: 349 XXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAAS 528
L+P+ E +F++ A+D I+N AAK YM G VP+V R P G S
Sbjct: 68 AGSAVGMALTGLRPVVEMRVVDFALCAMDEIVNQAAKNRYMFGGQGRVPMVIRMPIGIWS 127
Query: 529 SVAAQHSQCFGAWYSHCPGLKVLMP 603
S AAQHSQ AW++H PGL VL P
Sbjct: 128 SSAAQHSQSLEAWFAHVPGLVVLCP 152
>UniRef50_A0HHH4 Cluster: Transketolase, central region; n=2;
Bacteria|Rep: Transketolase, central region - Comamonas
testosteroni KF-1
Length = 334
Score = 107 bits (258), Expect = 2e-22
Identities = 53/152 (34%), Positives = 83/152 (54%)
Frame = +1
Query: 148 KALASKPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDT 327
+A ++ ++ A+N A+ + + + GE+VA+ G + VT+ L K++G RV DT
Sbjct: 5 QATSTLALSYAKAINAALSRALTHMPETLLFGEDVAKPGGVFGVTKDLQKEFGSARVFDT 64
Query: 328 PITEXXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFR 507
PI+E ++PI E M +FS+ A+D I+N AA Y+SAG + P+ R
Sbjct: 65 PISETAMLGTAVGAAMCGMRPIVEIMWIDFSLVAMDQIVNQAANVRYVSAGKLQAPMTIR 124
Query: 508 GPNGAASSVAAQHSQCFGAWYSHCPGLKVLMP 603
GA AQHSQ A ++H PGL+V +P
Sbjct: 125 TQQGALPGSCAQHSQNLEAMFAHVPGLRVGLP 156
>UniRef50_P35488 Cluster: Pyruvate dehydrogenase E1 component
subunit beta; n=4; Bacteria|Rep: Pyruvate dehydrogenase
E1 component subunit beta - Acholeplasma laidlawii
Length = 327
Score = 107 bits (258), Expect = 2e-22
Identities = 54/145 (37%), Positives = 73/145 (50%)
Frame = +1
Query: 169 VTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXX 348
+T+ +A+NQAID+ ME+DE + V GE+ G ++VT GL KKYG+ RV DTPI E
Sbjct: 4 ITLLEAINQAIDQAMEKDESIVVFGEDAGFEGGVFRVTAGLQKKYGETRVFDTPIAESAI 63
Query: 349 XXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAAS 528
LKPI E F ++ AA+ S G VP+V R P+G
Sbjct: 64 VGSAVGMAINGLKPIAEIQFDGFIFPGYTDLVTHAARMRNRSRGQFTVPMVLRLPHGGGI 123
Query: 529 SVAAQHSQCFGAWYSHCPGLKVLMP 603
HS+ + PGLKV+ P
Sbjct: 124 RALEHHSEALEVLFGSIPGLKVVTP 148
>UniRef50_A0LFE7 Cluster: Transketolase domain protein; n=1;
Syntrophobacter fumaroxidans MPOB|Rep: Transketolase
domain protein - Syntrophobacter fumaroxidans (strain
DSM 10017 / MPOB)
Length = 325
Score = 107 bits (257), Expect = 2e-22
Identities = 59/147 (40%), Positives = 79/147 (53%), Gaps = 2/147 (1%)
Frame = +1
Query: 169 VTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKV--TRGLWKKYGDKRVIDTPITEX 342
+T+ A+NQA+ EEM RD VF+ GE V A V T GL +++G RV DTP++E
Sbjct: 4 LTMGQAVNQALREEMLRDPNVFIAGEGVGVSIHAAPVLPTFGLLEEFGPDRVKDTPVSEA 63
Query: 343 XXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGA 522
L+P+ E M F A D I+N AAK Y+S G P+V R +GA
Sbjct: 64 AIAGLAVGASVMGLRPVVEIMFNPFVTLASDMIVNHAAKLRYLSGGKSTFPMVVRIKSGA 123
Query: 523 ASSVAAQHSQCFGAWYSHCPGLKVLMP 603
QHS AW +HCPG++V+MP
Sbjct: 124 GFKAGCQHSHNLEAWLAHCPGIRVVMP 150
>UniRef50_Q72GU2 Cluster: 2-oxoisovalerate dehydrogenase subunit
beta; n=12; cellular organisms|Rep: 2-oxoisovalerate
dehydrogenase subunit beta - Thermus thermophilus
(strain HB27 / ATCC BAA-163 / DSM 7039)
Length = 324
Score = 107 bits (256), Expect = 3e-22
Identities = 53/143 (37%), Positives = 77/143 (53%)
Frame = +1
Query: 169 VTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXX 348
+T+ ALN+A+DEEM +D +V VLGE+V + G + VT GL +KYG RV+DTP++E
Sbjct: 4 MTMVQALNRALDEEMAKDPRVVVLGEDVGKRGGVFLVTEGLLQKYGPDRVMDTPLSEAAI 63
Query: 349 XXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAAS 528
L+P+ E ++ D +++ AK Y S G P+V R P+G
Sbjct: 64 VGAALGMAAHGLRPVAEIQFADYIFPGFDQLVSQVAKLRYRSGGQFTAPLVVRMPSGGGV 123
Query: 529 SVAAQHSQCFGAWYSHCPGLKVL 597
HSQ A + H GLKV+
Sbjct: 124 RGGHHHSQSPEAHFVHTAGLKVV 146
>UniRef50_A0H598 Cluster: Transketolase, central region; n=2;
Chloroflexus|Rep: Transketolase, central region -
Chloroflexus aggregans DSM 9485
Length = 343
Score = 104 bits (250), Expect = 1e-21
Identities = 52/148 (35%), Positives = 78/148 (52%)
Frame = +1
Query: 160 SKPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITE 339
++ +T +A+ A+ EM+RD +V ++GE++ Y GA+KVT+GL +++G+ +VIDTP+TE
Sbjct: 20 TRELTYLEAIRAALRYEMQRDLRVLIMGEDIGVYGGAFKVTQGLIEEFGEDQVIDTPMTE 79
Query: 340 XXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNG 519
P+ E +F D I+ AA + PVPI R P G
Sbjct: 80 LAMIYAAIGMSFEGFLPVVEMQFADFISTGFDAIVQFAATNHF--RWRQPVPITIRAPGG 137
Query: 520 AASSVAAQHSQCFGAWYSHCPGLKVLMP 603
HSQ AW+ H PGLKV+ P
Sbjct: 138 GGLRAGPFHSQSNEAWFVHTPGLKVVAP 165
>UniRef50_Q5BSL1 Cluster: SJCHGC03862 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC03862 protein - Schistosoma
japonicum (Blood fluke)
Length = 91
Score = 104 bits (250), Expect = 1e-21
Identities = 46/74 (62%), Positives = 60/74 (81%)
Frame = +1
Query: 118 RLSRRSFATSKALASKPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWK 297
+L RS T+ ++ + +TVRDALN A+ EE+ERD+ V +LGEEVAQYDGAYK+T+GLWK
Sbjct: 17 QLCSRSIKTTSSVYTSKMTVRDALNSAMREELERDKDVIILGEEVAQYDGAYKITKGLWK 76
Query: 298 KYGDKRVIDTPITE 339
+GD RV+DTPITE
Sbjct: 77 TFGDSRVMDTPITE 90
>UniRef50_A7BPK5 Cluster: Pyruvate dehydrogenase, E1 component, beta
subunit; n=1; Beggiatoa sp. PS|Rep: Pyruvate
dehydrogenase, E1 component, beta subunit - Beggiatoa
sp. PS
Length = 362
Score = 103 bits (247), Expect = 3e-21
Identities = 54/149 (36%), Positives = 78/149 (52%)
Frame = +1
Query: 157 ASKPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPIT 336
+ + +T A+ + + + ME+D V V+GE V + T GL +++G KRV D P+
Sbjct: 7 SQRELTYSQAILEGLRQCMEQDSSVIVIGEGVPDPKAIFGTTEGLLEQFGPKRVFDMPLA 66
Query: 337 EXXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPN 516
E L+P+ +FS+ A+D IIN+AAK YM G V VP+V R
Sbjct: 67 ENGMTGICIGAALDGLRPVMVHQRIDFSLLALDQIINNAAKWHYMFDGAVSVPLVIRVLI 126
Query: 517 GAASSVAAQHSQCFGAWYSHCPGLKVLMP 603
G QHSQ A ++H PGLKV+MP
Sbjct: 127 GRGWGQGPQHSQSLQALFAHIPGLKVVMP 155
>UniRef50_Q9Z9E8 Cluster: (Pyruvate) Oxoisovalerate Dehydrogenase
Alpha/Beta Fusion ((Pyruvate) oxoisovalerate
dehydrogenase alpha and beta fusion); n=7;
Chlamydiaceae|Rep: (Pyruvate) Oxoisovalerate
Dehydrogenase Alpha/Beta Fusion ((Pyruvate)
oxoisovalerate dehydrogenase alpha and beta fusion) -
Chlamydia pneumoniae (Chlamydophila pneumoniae)
Length = 678
Score = 102 bits (245), Expect = 6e-21
Identities = 52/150 (34%), Positives = 80/150 (53%), Gaps = 2/150 (1%)
Frame = +1
Query: 160 SKPVTVRDALNQAIDEEMERDEKVFVLGEEVA-QYDGAYKVTRGLWKKYGDKRVIDTPIT 336
S+P +RDA+++A+ EEM RD V V GE+VA G + VTR L +K+G +R ++P+
Sbjct: 348 SEPKVMRDAISEALVEEMTRDSGVIVFGEDVAGDKGGVFGVTRNLTEKFGPQRCFNSPLA 407
Query: 337 EXXXXXXXXXXXXXXL-KPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGP 513
E + KP+ E ++ I+ + + A+ +Y SAG VP+V R P
Sbjct: 408 EATIIGTAIGMALDGIHKPVVEIQFADYIWPGINQLFSEASSIYYRSAGEWEVPLVIRAP 467
Query: 514 NGAASSVAAQHSQCFGAWYSHCPGLKVLMP 603
+G HSQ + +HCPG+KV P
Sbjct: 468 SGGYIQGGPYHSQSIEGFLAHCPGIKVAYP 497
>UniRef50_Q9KG98 Cluster: Pyruvate dehydrogenase E1 (Lipoamide) beta
subunit; n=24; Bacteria|Rep: Pyruvate dehydrogenase E1
(Lipoamide) beta subunit - Bacillus halodurans
Length = 328
Score = 101 bits (241), Expect = 2e-20
Identities = 49/150 (32%), Positives = 79/150 (52%)
Frame = +1
Query: 154 LASKPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPI 333
+ S+ T+ A+NQ +D+ + ++ V +LGE++ G ++ T GL++KYG RV+DTP+
Sbjct: 1 MGSQQQTMLQAINQTLDDLLATNDDVMLLGEDIGINGGVFRATDGLYEKYGKDRVVDTPL 60
Query: 334 TEXXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGP 513
E +PI E F + +I+ AA+ Y + G VP+V R P
Sbjct: 61 AESGIIGSAIGLAMNGKRPIVEIQFLAFIYPGFEQLISHAARMRYRTRGQYNVPMVIRTP 120
Query: 514 NGAASSVAAQHSQCFGAWYSHCPGLKVLMP 603
GA HS+ A+++H PGLKV+ P
Sbjct: 121 YGAGIRGPELHSESVEAFFAHTPGLKVVAP 150
>UniRef50_A5UVZ0 Cluster: Transketolase, central region; n=5;
Bacteria|Rep: Transketolase, central region -
Roseiflexus sp. RS-1
Length = 327
Score = 100 bits (240), Expect = 2e-20
Identities = 53/145 (36%), Positives = 76/145 (52%)
Frame = +1
Query: 169 VTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXX 348
+T +A+ A+ + M D+++ VLGE+VA G + T GL ++G++RVID PI E
Sbjct: 4 MTFIEAIRSAMHDAMAADDRIIVLGEDVAVRGGVFLATEGLLARFGERRVIDMPIAECAI 63
Query: 349 XXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAAS 528
L PI E ++ AID I+N AA+ Y S G PIV R P GA
Sbjct: 64 VGVAIGAALHGLLPIAEIQFADYIYPAIDQILNEAARLRYRSNGDWSCPIVVRAPFGAGI 123
Query: 529 SVAAQHSQCFGAWYSHCPGLKVLMP 603
A HSQ ++ PG+KV++P
Sbjct: 124 HGALYHSQSVERLFTSTPGIKVVIP 148
>UniRef50_Q5UWH0 Cluster: Pyruvate dehydrogenase; n=55; cellular
organisms|Rep: Pyruvate dehydrogenase - Haloarcula
marismortui (Halobacterium marismortui)
Length = 338
Score = 99 bits (238), Expect = 4e-20
Identities = 49/148 (33%), Positives = 78/148 (52%)
Frame = +1
Query: 160 SKPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITE 339
++ +T+ +A+ + EM +D+ V VLGE+V + G ++ T L++++G+ RVIDTP+ E
Sbjct: 13 AQSLTLVEAIQDGLYTEMSQDDTVVVLGEDVGKNGGVFRATDQLYEEFGEDRVIDTPLAE 72
Query: 340 XXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNG 519
+KP+ E F A D I++ AA+ S G VP+V R P G
Sbjct: 73 AGIIGASIGLAQTGMKPVPEMQFMGFMYPAFDQIVSHAARLRSRSQGQYSVPMVIRAPYG 132
Query: 520 AASSVAAQHSQCFGAWYSHCPGLKVLMP 603
HS+ A++ H PGLKV+ P
Sbjct: 133 GGIRAPEHHSESKEAFFVHEPGLKVVSP 160
>UniRef50_O34591 Cluster: Acetoin:2,6-dichlorophenolindophenol
oxidoreductase subunit beta; n=65; Bacteria|Rep:
Acetoin:2,6-dichlorophenolindophenol oxidoreductase
subunit beta - Bacillus subtilis
Length = 342
Score = 99 bits (238), Expect = 4e-20
Identities = 56/160 (35%), Positives = 82/160 (51%), Gaps = 12/160 (7%)
Frame = +1
Query: 160 SKPVTVRDALNQAIDEEMERDEKVFVLGEEVA------------QYDGAYKVTRGLWKKY 303
++ +++ DA+N+A+ M +DE V ++GE+VA + G VT+GL +++
Sbjct: 2 ARVISMSDAINEAMKLAMRKDENVLLIGEDVAGGAAVDHLQDDEAWGGVLGVTKGLVQEF 61
Query: 304 GDKRVIDTPITEXXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGT 483
G RV+DTPI+E L+PI E M +F D +IN AK YM G
Sbjct: 62 GRTRVLDTPISEAGYMGAAMAAASTGLRPIAELMFNDFIGTCFDQVINQGAKFRYMFGGK 121
Query: 484 VPVPIVFRGPNGAASSVAAQHSQCFGAWYSHCPGLKVLMP 603
VPI R GA AAQHSQ ++ PGLK ++P
Sbjct: 122 AQVPITVRTTYGAGFRAAAQHSQSLYGLFTSIPGLKTVVP 161
>UniRef50_Q4DEQ0 Cluster: 2-oxoisovalerate dehydrogenase beta
subunit, mitochondrial, putative; n=2; Trypanosoma
cruzi|Rep: 2-oxoisovalerate dehydrogenase beta subunit,
mitochondrial, putative - Trypanosoma cruzi
Length = 368
Score = 99.5 bits (237), Expect = 5e-20
Identities = 51/141 (36%), Positives = 74/141 (52%), Gaps = 1/141 (0%)
Frame = +1
Query: 184 ALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXXXX 363
A+N A+D + RDEK V GE+VA + G ++ T L KKYG +RV D+P++E
Sbjct: 54 AINSALDLALSRDEKTVVFGEDVA-FGGVFRCTLNLSKKYGSQRVFDSPLSEQGLVGFAI 112
Query: 364 XXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPV-PIVFRGPNGAASSVAA 540
KPI E ++ A D I+N AAK + S G +V R P+ A
Sbjct: 113 GMASAGWKPIAEVQFADYIFPAFDQIVNEAAKMRFRSGGHFHCGGLVIRSPSSAVGHGGL 172
Query: 541 QHSQCFGAWYSHCPGLKVLMP 603
HSQ +++HC G+K++MP
Sbjct: 173 YHSQSVEGFFNHCAGIKIVMP 193
>UniRef50_A0JY24 Cluster: Transketolase, central region; n=2;
cellular organisms|Rep: Transketolase, central region -
Arthrobacter sp. (strain FB24)
Length = 354
Score = 98.3 bits (234), Expect = 1e-19
Identities = 49/145 (33%), Positives = 74/145 (51%)
Frame = +1
Query: 169 VTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXX 348
++++ ALN+A+DE + + K V GE+ + G +++T GL KYG RV DTP+ E
Sbjct: 24 LSMQQALNRALDEVLAGNPKSLVFGEDCGRLGGVFRITDGLQAKYGPGRVFDTPLAESGI 83
Query: 349 XXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAAS 528
PI E F+ AI+ I+ A+ Y S GT+P+PI R P+
Sbjct: 84 LGMSVGLAMAGFHPIPEVQFDGFAYPAINQIVCQIARMNYRSRGTMPMPITLRVPSFGGI 143
Query: 529 SVAAQHSQCFGAWYSHCPGLKVLMP 603
H + A ++H PGLKV+ P
Sbjct: 144 RAPEHHGESLEALFAHVPGLKVVSP 168
>UniRef50_A5ACP6 Cluster: Putative uncharacterized protein; n=1;
Vitis vinifera|Rep: Putative uncharacterized protein -
Vitis vinifera (Grape)
Length = 360
Score = 98.3 bits (234), Expect = 1e-19
Identities = 55/147 (37%), Positives = 83/147 (56%), Gaps = 7/147 (4%)
Frame = +1
Query: 79 ALKSSPAVLG---MLTR-LSRRSFATSKALASKP---VTVRDALNQAIDEEMERDEKVFV 237
+L SSP G ++T ++ ++ A++ + ASKP + + +AL + ++EEM+RD V V
Sbjct: 45 SLGSSPRSRGAQHLITNAVAAKADASATSTASKPGHELLLFEALREGLEEEMDRDPLVCV 104
Query: 238 LGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXXXXXXXXXXLKPICEFMTFNF 417
+GE+V Y G+YKVT+GL KYGD RV+DTPI E L+PI E M F
Sbjct: 105 MGEDVGHYGGSYKVTKGLAAKYGDLRVLDTPIAENSFTGMGIGAAMTGLRPIIEGMNMGF 164
Query: 418 SMQAIDHIINSAAKTFYMSAGTVPVPI 498
+ A + I N+ Y S G +P+
Sbjct: 165 LLLAFNQISNNCGMLHYTSGGQFKIPV 191
>UniRef50_Q0W152 Cluster: Pyruvate dehydrogenase complex E1,
transketolase beta subunit; n=8; cellular organisms|Rep:
Pyruvate dehydrogenase complex E1, transketolase beta
subunit - Uncultured methanogenic archaeon RC-I
Length = 325
Score = 96.7 bits (230), Expect = 4e-19
Identities = 47/140 (33%), Positives = 72/140 (51%)
Frame = +1
Query: 184 ALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXXXX 363
A+N A+ EM RD V V+GE+V + G ++ T GL +K+G +RV+DTP++E
Sbjct: 9 AVNDALMVEMGRDPSVIVMGEDVGKEGGVFRATTGLQEKFGRERVVDTPLSENGIIGTAI 68
Query: 364 XXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASSVAAQ 543
+KP+CE F + +I A++ + G VP+V R P G
Sbjct: 69 GLALNGIKPVCEIQFSGFVYAGYEELIAHASRIRQRTMGRFSVPMVVRMPYGGGVKALEH 128
Query: 544 HSQCFGAWYSHCPGLKVLMP 603
HS+ + + H PGLKV+ P
Sbjct: 129 HSESYETIFLHDPGLKVVAP 148
>UniRef50_Q9I1M1 Cluster: 2-oxoisovalerate dehydrogenase subunit
beta; n=67; cellular organisms|Rep: 2-oxoisovalerate
dehydrogenase subunit beta - Pseudomonas aeruginosa
Length = 350
Score = 96.7 bits (230), Expect = 4e-19
Identities = 51/145 (35%), Positives = 74/145 (51%)
Frame = +1
Query: 169 VTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXX 348
+T+ AL A+D +ERD+ V V G++V + G ++ T GL KKYG RV D PI+E
Sbjct: 17 MTMIQALRSAMDIMLERDDDVVVFGQDVGYFGGVFRCTEGLQKKYGTSRVFDAPISESGI 76
Query: 349 XXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAAS 528
L+P+ E ++ A D +I+ AA+ Y SAG VP+ R P G
Sbjct: 77 IGAAVGMGAYGLRPVVEIQFADYVYPASDQLISEAARLRYRSAGDFIVPMTVRMPCGGGI 136
Query: 529 SVAAQHSQCFGAWYSHCPGLKVLMP 603
HSQ A ++ GL+ +MP
Sbjct: 137 YGGQTHSQSPEAMFTQVCGLRTVMP 161
>UniRef50_Q479Q1 Cluster: Transketolase, central
region:Transketolase, C-terminal precursor; n=2;
Rhodocyclaceae|Rep: Transketolase, central
region:Transketolase, C-terminal precursor -
Dechloromonas aromatica (strain RCB)
Length = 337
Score = 95.5 bits (227), Expect = 9e-19
Identities = 52/145 (35%), Positives = 72/145 (49%)
Frame = +1
Query: 169 VTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXX 348
+T+ DA+ A+ EEM RD KV GE +A L ++G RV +TP+ E
Sbjct: 4 LTLNDAIGLALAEEMRRDHKVIAFGEGIATK------RHELVTEFGALRVRNTPLAEGII 57
Query: 349 XXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAAS 528
L+P+ + + F A+D ++NSA K YMS G P+V GA
Sbjct: 58 AGTAAGAAAGGLRPVADLLFAPFLCYAMDELVNSAGKLRYMSGGQFSFPLVALAMTGAGW 117
Query: 529 SVAAQHSQCFGAWYSHCPGLKVLMP 603
V AQH+ AW+ H PGLKV+MP
Sbjct: 118 GVGAQHNHNVEAWFVHSPGLKVVMP 142
>UniRef50_P0A0A3 Cluster: Pyruvate dehydrogenase E1 component
subunit beta; n=33; cellular organisms|Rep: Pyruvate
dehydrogenase E1 component subunit beta - Staphylococcus
aureus
Length = 325
Score = 93.1 bits (221), Expect = 5e-18
Identities = 44/145 (30%), Positives = 69/145 (47%)
Frame = +1
Query: 169 VTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXX 348
+T+ A+N A+ E++ D+ V + GE+V G ++VT GL K++G+ RV DTP+ E
Sbjct: 4 MTMVQAINDALKTELKNDQDVLIFGEDVGVNGGVFRVTEGLQKEFGEDRVFDTPLAESGI 63
Query: 349 XXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAAS 528
+P+ E F + D I A+T + S GT P+ R P G
Sbjct: 64 GGLAMGLAVEGFRPVMEVQFLGFVFEVFDAIAGQIARTRFRSGGTKTAPVTIRSPFGGGV 123
Query: 529 SVAAQHSQCFGAWYSHCPGLKVLMP 603
H+ + PGLKV++P
Sbjct: 124 HTPELHADNLEGILAQSPGLKVVIP 148
>UniRef50_P75391 Cluster: Pyruvate dehydrogenase E1 component
subunit beta; n=23; Mollicutes|Rep: Pyruvate
dehydrogenase E1 component subunit beta - Mycoplasma
pneumoniae
Length = 327
Score = 93.1 bits (221), Expect = 5e-18
Identities = 50/141 (35%), Positives = 66/141 (46%)
Frame = +1
Query: 181 DALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXXX 360
+AL A+D +ERD V + G++ G ++ T+GL KKYG++RV D PI E
Sbjct: 11 EALGNAMDLALERDPNVVLYGQDAGFEGGVFRATKGLQKKYGEERVWDCPIAEAAMAGIG 70
Query: 361 XXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASSVAA 540
LKPI E FS A+ I AA+ S G PI+ R P G
Sbjct: 71 VGAAIGGLKPIVEIQFSGFSFPAMFQIFTHAARIRNRSRGVYTCPIIVRMPMGGGIKALE 130
Query: 541 QHSQCFGAWYSHCPGLKVLMP 603
HS+ A Y GLK +MP
Sbjct: 131 HHSETLEAIYGQIAGLKTVMP 151
>UniRef50_A1RJV5 Cluster: Transketolase, central region; n=18;
cellular organisms|Rep: Transketolase, central region -
Shewanella sp. (strain W3-18-1)
Length = 325
Score = 90.6 bits (215), Expect = 2e-17
Identities = 46/141 (32%), Positives = 73/141 (51%), Gaps = 1/141 (0%)
Frame = +1
Query: 184 ALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXXXX 363
A+N+A+ M+ DE++ V GE+V + G ++ T GL +K+G R +TP+TE
Sbjct: 9 AVNEALSIAMQADERMVVFGEDVGHFGGVFRATSGLQEKFGRARCFNTPLTEQGIAGFAN 68
Query: 364 XXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPV-PIVFRGPNGAASSVAA 540
+ + E ++ A D I+N +AK Y S V +VFR P G +
Sbjct: 69 GLASNGMTAVAEIQFADYIFPAFDQIVNESAKFRYRSGNEFDVGGLVFRTPYGGGIAGGH 128
Query: 541 QHSQCFGAWYSHCPGLKVLMP 603
HSQ A+++ PGLKV++P
Sbjct: 129 YHSQSPEAYFTQTPGLKVVVP 149
>UniRef50_Q2BFQ9 Cluster: Putative uncharacterized protein; n=1;
Bacillus sp. NRRL B-14911|Rep: Putative uncharacterized
protein - Bacillus sp. NRRL B-14911
Length = 668
Score = 90.2 bits (214), Expect = 3e-17
Identities = 52/142 (36%), Positives = 71/142 (50%), Gaps = 1/142 (0%)
Frame = +1
Query: 181 DALNQAIDEEMERDEKVFVLGEEVAQ-YDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXX 357
D+LN A+ E D V ++GE++ Y GA+KV++GL KY D RV+ TPI+E
Sbjct: 342 DSLNNALHELFNEDGDVLLIGEDLLDPYGGAFKVSKGLSTKYPD-RVLTTPISEGGILGL 400
Query: 358 XXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASSVA 537
LKPI E M +F D ++N A+K +M V VP+V R P G
Sbjct: 401 STGLAMRGLKPIAEIMFGDFLALGADQLLNHASKYQWMYNNKVEVPLVVRAPMGGKRGYG 460
Query: 538 AQHSQCFGAWYSHCPGLKVLMP 603
HSQ + PGL V+ P
Sbjct: 461 PTHSQSIEKMFFGIPGLTVVSP 482
>UniRef50_Q1ARM1 Cluster: Transketolase-like protein; n=2;
Bacteria|Rep: Transketolase-like protein - Rubrobacter
xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 330
Score = 90.2 bits (214), Expect = 3e-17
Identities = 49/140 (35%), Positives = 76/140 (54%)
Frame = +1
Query: 184 ALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXXXX 363
A+ + + + M D+ V V+GE+V + TRGL +++G +RV +TPI+E
Sbjct: 12 AMYEGLRDAMREDKTVVVIGEDVDR--SIIGATRGLIEEFGPERVRNTPISEATFVGACI 69
Query: 364 XXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASSVAAQ 543
L+P+ + M +F A+D + N AAK YMS G V +PIV+ G + S AAQ
Sbjct: 70 GASAAGLRPVVDLMVGSFFYVAMDQVANQAAKLPYMSGGQVSLPIVYFTATGPSGSAAAQ 129
Query: 544 HSQCFGAWYSHCPGLKVLMP 603
HS+ + GLK++MP
Sbjct: 130 HSENPHPMLMNVAGLKIVMP 149
>UniRef50_A7CXF2 Cluster: Transketolase central region; n=1;
Opitutaceae bacterium TAV2|Rep: Transketolase central
region - Opitutaceae bacterium TAV2
Length = 398
Score = 89.4 bits (212), Expect = 6e-17
Identities = 47/153 (30%), Positives = 75/153 (49%)
Frame = +1
Query: 145 SKALASKPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVID 324
S A +T+ A+N A+ + + + +LG+++ Y GA+KVT L + +G RV +
Sbjct: 67 SLCTAPAHLTMAQAINAALRKILAERPESLLLGQDIGVYGGAFKVTENLLRDFGRTRVFN 126
Query: 325 TPITEXXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVF 504
TP+ E +PI EF +FS +A+ I +AA Y + VP+V+
Sbjct: 127 TPLAESACTGYATGLALGGYRPIEEFQFADFSTEAVTQITQNAATYHYRTGAAAKVPVVY 186
Query: 505 RGPNGAASSVAAQHSQCFGAWYSHCPGLKVLMP 603
R P G +V + HSQ + PG+K L P
Sbjct: 187 RFPCGGGITVGSFHSQELETLFLAFPGIKALYP 219
>UniRef50_Q6ABX8 Cluster: Pyruvate dehydrogenase E1 component
subunit beta; n=60; cellular organisms|Rep: Pyruvate
dehydrogenase E1 component subunit beta - Leifsonia xyli
subsp. xyli
Length = 337
Score = 89.0 bits (211), Expect = 8e-17
Identities = 42/140 (30%), Positives = 66/140 (47%)
Frame = +1
Query: 184 ALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXXXX 363
ALN + + + D KV +LGE+V G ++VT GL ++G RV+DTP+ E
Sbjct: 22 ALNAGLRQALVADPKVLILGEDVGPLGGVFRVTEGLQSEFGASRVVDTPLAEAGIVGTAI 81
Query: 364 XXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASSVAAQ 543
+P+ E F D I AK +G V +P+V R P+G
Sbjct: 82 GLAMRGYRPVVEIQFNGFVFPGFDQITTQLAKMANRHSGAVSMPVVIRIPHGGHIGAVEH 141
Query: 544 HSQCFGAWYSHCPGLKVLMP 603
H + A+++H GL+++ P
Sbjct: 142 HQEAPEAYFAHTAGLRIVAP 161
>UniRef50_P21882 Cluster: Pyruvate dehydrogenase E1 component
subunit beta; n=41; cellular organisms|Rep: Pyruvate
dehydrogenase E1 component subunit beta - Bacillus
subtilis
Length = 325
Score = 87.8 bits (208), Expect = 2e-16
Identities = 42/145 (28%), Positives = 67/145 (46%)
Frame = +1
Query: 169 VTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXX 348
+T+ A+ A+ E++ DE V V GE+V G ++ T GL K++G+ RV DTP+ E
Sbjct: 4 MTMIQAITDALRTELKNDENVLVFGEDVGVNGGVFRATEGLQKEFGEDRVFDTPLAESGI 63
Query: 349 XXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAAS 528
+P+ E F F + +D + A+ Y S G P+ R P G
Sbjct: 64 GGLALGLGLNGFRPVMEIQFFGFVYEVMDSVSGQMARMRYRSGGRWTSPVTIRSPFGGGV 123
Query: 529 SVAAQHSQCFGAWYSHCPGLKVLMP 603
H+ + PG+KV++P
Sbjct: 124 HTPELHADSLEGLVAQQPGIKVVIP 148
>UniRef50_Q023C4 Cluster: Pyruvate dehydrogenase; n=1; Solibacter
usitatus Ellin6076|Rep: Pyruvate dehydrogenase -
Solibacter usitatus (strain Ellin6076)
Length = 397
Score = 87.4 bits (207), Expect = 2e-16
Identities = 52/151 (34%), Positives = 72/151 (47%), Gaps = 1/151 (0%)
Frame = +1
Query: 154 LASKPVTVRDALNQAIDEEMERDEKVFVLGEEVAQ-YDGAYKVTRGLWKKYGDKRVIDTP 330
LA KPVT+ DA+N + EEMER+ K+ + GE++A G + VTRGL RV + P
Sbjct: 68 LAEKPVTMIDAINHGLREEMERNPKIVMWGEDIADPKGGVFGVTRGLSSALPG-RVFNAP 126
Query: 331 ITEXXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRG 510
+ E KPI E +++ A + N A + S GT P+V R
Sbjct: 127 LAEASIAGVAAGMAIAGYKPIIEIQFADYTWPAFMQLRNEIATVRWRSQGTWNCPVVVRI 186
Query: 511 PNGAASSVAAQHSQCFGAWYSHCPGLKVLMP 603
GA HS C ++H PG +VL P
Sbjct: 187 AAGAYIKGGPWHSACVEGVFAHIPGWRVLFP 217
>UniRef50_A5V556 Cluster: Transketolase domain protein; n=1;
Sphingomonas wittichii RW1|Rep: Transketolase domain
protein - Sphingomonas wittichii RW1
Length = 330
Score = 86.2 bits (204), Expect = 5e-16
Identities = 48/144 (33%), Positives = 77/144 (53%)
Frame = +1
Query: 172 TVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXX 351
T +A+ QA EEM RDE+VF++GE++ + T G +G +RV DTPI+E
Sbjct: 5 TFLEAIRQAQYEEMTRDERVFIMGEDIIC--NVFGTTTGFVDAFGTERVRDTPISENGFI 62
Query: 352 XXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASS 531
++PI + +F A+D I++ AK+ Y+ G +P+V R +S
Sbjct: 63 GAAGGAAMVGMRPIVDATISSFLYPAMDQIMSIIAKSRYIYGGQARLPLVIRSCLFYGNS 122
Query: 532 VAAQHSQCFGAWYSHCPGLKVLMP 603
AAQHS + + + PGLK+++P
Sbjct: 123 NAAQHSDRNYSMFMNVPGLKIMVP 146
>UniRef50_Q7N3C2 Cluster: Similar to 3-methyl-2-oxobutanoate
dehydrogenase; n=1; Photorhabdus luminescens subsp.
laumondii|Rep: Similar to 3-methyl-2-oxobutanoate
dehydrogenase - Photorhabdus luminescens subsp.
laumondii
Length = 650
Score = 85.0 bits (201), Expect = 1e-15
Identities = 63/183 (34%), Positives = 87/183 (47%), Gaps = 3/183 (1%)
Frame = +1
Query: 58 SDIIFKMALKSSPAVLGMLTRLSRRSFATSKALASKPVTVR--DALNQAIDEEMERDEKV 231
+D I K S G T+L RS +T L S+ +R A+N+A E ME D+ +
Sbjct: 277 NDAIRKAKQARSSPFYGAETQLQSRS-STFHPLPSQGSKIRLSRAINKAFLEIMELDKNI 335
Query: 232 FVLGEEV-AQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXXXXXXXXXXLKPICEFMT 408
+GE+V A Y GA+K++ GL + ++ VI+TPI+E P E M
Sbjct: 336 LFIGEDVKAPYGGAFKISDGLSDSFPEQ-VINTPISESAIVGIGCGLAMHGYCPFVEIMF 394
Query: 409 FNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASSVAAQHSQCFGAWYSHCPGL 588
+F A D I+N AAK M V VP+V R P GA HSQ + PGL
Sbjct: 395 GDFLTLAFDQILNHAAKFRDMYNDQVKVPLVIRTPMGAGRGYGPTHSQTLEKHFMGIPGL 454
Query: 589 KVL 597
+L
Sbjct: 455 TIL 457
>UniRef50_Q319T3 Cluster: Pyruvate dehydrogenase; n=1;
Prochlorococcus marinus str. MIT 9312|Rep: Pyruvate
dehydrogenase - Prochlorococcus marinus (strain MIT
9312)
Length = 329
Score = 85.0 bits (201), Expect = 1e-15
Identities = 49/147 (33%), Positives = 70/147 (47%)
Frame = +1
Query: 163 KPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEX 342
K T A+ A + ++ +VFV+G+ + + L K +G KR+IDTP++E
Sbjct: 2 KKFTYSTAILDAYNFLLKNYPEVFVIGQGLWSPWYVGNTMKDLDKNFGKKRIIDTPVSEA 61
Query: 343 XXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGA 522
+KPI +F M A+D IIN AAK YM G I RG
Sbjct: 62 AVTGAAVGASLNEMKPIVVHPRMDFMMYAMDPIINQAAKWSYMFGGQSSPSITIRGIINR 121
Query: 523 ASSVAAQHSQCFGAWYSHCPGLKVLMP 603
AQHSQ + ++H PGLKV++P
Sbjct: 122 GGEQGAQHSQALHSLFAHIPGLKVVLP 148
>UniRef50_Q83DL8 Cluster: Dehydrogenase, E1 component, beta subunit;
n=9; Proteobacteria|Rep: Dehydrogenase, E1 component,
beta subunit - Coxiella burnetii
Length = 353
Score = 84.6 bits (200), Expect = 2e-15
Identities = 43/139 (30%), Positives = 67/139 (48%)
Frame = +1
Query: 187 LNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXXXXX 366
+N A+ + M+ D V G + + T GL +++G+ RV D P E
Sbjct: 10 INAALRKAMQIDPSVLCYGLGINDSARIFGTTTGLVEEFGEDRVFDMPTAENAMTGVGIG 69
Query: 367 XXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASSVAAQH 546
+P+ +F++ ++D IIN AAK + + AGT+PVP+ R G H
Sbjct: 70 LAINGFRPVLSHCRLDFALLSLDQIINGAAKWYSLFAGTMPVPLTIRAIVGRGWGQGPTH 129
Query: 547 SQCFGAWYSHCPGLKVLMP 603
Q A ++H PGLKV+MP
Sbjct: 130 CQSLQACFAHIPGLKVVMP 148
>UniRef50_Q83X27 Cluster: Probable pyruvate dehydrogenase
beta-subunit; n=1; Streptomyces rochei|Rep: Probable
pyruvate dehydrogenase beta-subunit - Streptomyces
rochei (Streptomyces parvullus)
Length = 344
Score = 84.6 bits (200), Expect = 2e-15
Identities = 48/147 (32%), Positives = 68/147 (46%)
Frame = +1
Query: 163 KPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEX 342
+ +T A+++A + ME D + + G+ V Y G Y T + ++G RVID P E
Sbjct: 2 RSLTYSQAISEATVQCMEADPAIVLAGQSVDDYKGVYGTTGEAFARFGSARVIDIPNGEN 61
Query: 343 XXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGA 522
L+P+ +F A+D +IN AAK YM G VP+V RG G
Sbjct: 62 AFAGIAIGAATMGLRPLLVHTRDDFMFLAMDALINLAAKWRYMYGGKRGVPVVSRGVVGR 121
Query: 523 ASSVAAQHSQCFGAWYSHCPGLKVLMP 603
A HSQ + + H PGL V P
Sbjct: 122 GWGQGATHSQSLQSLFGHFPGLHVATP 148
>UniRef50_A0M1U4 Cluster: 2-oxoisovalerate dehydrogenase E1
component subunits alpha and beta; n=18;
Bacteroidetes|Rep: 2-oxoisovalerate dehydrogenase E1
component subunits alpha and beta - Gramella forsetii
(strain KT0803)
Length = 685
Score = 84.6 bits (200), Expect = 2e-15
Identities = 43/141 (30%), Positives = 70/141 (49%)
Frame = +1
Query: 181 DALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXXX 360
DA++QA+ E +++ E + ++G+++A Y G +K+T G +++G R+ +TPI E
Sbjct: 372 DAISQALKESVKKHENLVLMGQDIADYGGVFKITEGFVEEFGKDRIRNTPICESAIVGAA 431
Query: 361 XXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASSVAA 540
+K + E +F + I+N AK Y V V R P G
Sbjct: 432 MGLSINGMKAMVEMQFSDFVSSGFNPIVNYLAKVKYRWDQNADV--VLRMPCGGGVGAGP 489
Query: 541 QHSQCFGAWYSHCPGLKVLMP 603
HSQ AW++ PGLKV+ P
Sbjct: 490 FHSQTNEAWFTKVPGLKVIYP 510
>UniRef50_Q020J5 Cluster: Dehydrogenase, E1 component; n=1;
Solibacter usitatus Ellin6076|Rep: Dehydrogenase, E1
component - Solibacter usitatus (strain Ellin6076)
Length = 697
Score = 83.0 bits (196), Expect = 5e-15
Identities = 49/170 (28%), Positives = 76/170 (44%), Gaps = 13/170 (7%)
Frame = +1
Query: 133 SFATSKALASKPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYD------------GAYK 276
+F P+T+ D +N + EEM R+ + V GE+VA G +K
Sbjct: 346 AFHAEPRFQGAPMTMVDLINATLREEMRRNPDILVFGEDVADASREQNLTEVKGKGGVFK 405
Query: 277 VTRGLWKKYGDKRVIDTPITEXXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAA 456
VT GL ++G +R + PI E LKP+ E F++ A+ + + A
Sbjct: 406 VTHGLQSEFGARRAFNAPIAEAAIVGRAIGMAARGLKPVAEIQFFDYIWPAMMQLRDELA 465
Query: 457 KTFYMSAGTVPVPIVFRGP-NGAASSVAAQHSQCFGAWYSHCPGLKVLMP 603
+ S G P + R P G + A HSQC + ++H PGL+V+ P
Sbjct: 466 TMRWRSNGAFSAPAIIRVPIGGYLNGGAIYHSQCGESIFTHIPGLRVVFP 515
>UniRef50_A1G854 Cluster: Transketolase, central region; n=3;
Actinomycetales|Rep: Transketolase, central region -
Salinispora arenicola CNS205
Length = 321
Score = 82.2 bits (194), Expect = 9e-15
Identities = 47/146 (32%), Positives = 78/146 (53%), Gaps = 1/146 (0%)
Frame = +1
Query: 169 VTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXX 348
++ R ALN+A+ +E+ RDE+VF+LGE++ A VT GL K++G +RV DTP++E
Sbjct: 4 LSYRKALNRALADELARDEEVFLLGEDIRV--AASAVTAGLLKRFGPERVRDTPLSEQAF 61
Query: 349 XXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGP-NGAA 525
+P+ EF + I+N A K M+ G VP+ + P +G+
Sbjct: 62 TSFATGAAMAGARPVVEFQIPALLFLVFEQIVNHAHKFPLMTGGQCSVPVTYLVPGSGSR 121
Query: 526 SSVAAQHSQCFGAWYSHCPGLKVLMP 603
+ A QHS + ++H G+ ++P
Sbjct: 122 TGWAGQHSDHPYSLFAHV-GVTTVVP 146
>UniRef50_P21953 Cluster: 2-oxoisovalerate dehydrogenase subunit
beta, mitochondrial precursor; n=84; cellular
organisms|Rep: 2-oxoisovalerate dehydrogenase subunit
beta, mitochondrial precursor - Homo sapiens (Human)
Length = 392
Score = 82.2 bits (194), Expect = 9e-15
Identities = 45/141 (31%), Positives = 67/141 (47%), Gaps = 1/141 (0%)
Frame = +1
Query: 184 ALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXXXX 363
++ A+D + +D + GE+VA + G ++ T GL KYG RV +TP+ E
Sbjct: 76 SVTSALDNSLAKDPTAVIFGEDVA-FGGVFRCTVGLRDKYGKDRVFNTPLCEQGIVGFGI 134
Query: 364 XXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPV-PIVFRGPNGAASSVAA 540
I E ++ A D I+N AAK Y S + R P G A
Sbjct: 135 GIAVTGATAIAEIQFADYIFPAFDQIVNEAAKYRYRSGDLFNCGSLTIRSPWGCVGHGAL 194
Query: 541 QHSQCFGAWYSHCPGLKVLMP 603
HSQ A+++HCPG+KV++P
Sbjct: 195 YHSQSPEAFFAHCPGIKVVIP 215
>UniRef50_A4XHV5 Cluster: Transketolase, central region; n=3;
Bacteria|Rep: Transketolase, central region -
Caldicellulosiruptor saccharolyticus (strain ATCC 43494
/ DSM 8903)
Length = 823
Score = 81.0 bits (191), Expect = 2e-14
Identities = 50/148 (33%), Positives = 76/148 (51%)
Frame = +1
Query: 160 SKPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITE 339
+K +RDA+ +A+ ++ D + GE++ + GA+ V RGL + R+ +T I+E
Sbjct: 473 AKVFNLRDAIFEALIDKFYTDPTLISYGEDLRDWGGAFAVYRGLTESLPYHRLFNTSISE 532
Query: 340 XXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNG 519
+ + E M +F +A D I N AK MSAGT+ +P+V R G
Sbjct: 533 GAIVGSAVGYGMCGGRVVVEIMYCDFIGRAGDEIFNQLAKWQAMSAGTLKMPVVVRVSVG 592
Query: 520 AASSVAAQHSQCFGAWYSHCPGLKVLMP 603
S AQHSQ + + SH PGLKV+ P
Sbjct: 593 --SKYGAQHSQDWSSIVSHIPGLKVVFP 618
>UniRef50_A4XF90 Cluster: Transketolase domain protein; n=1;
Novosphingobium aromaticivorans DSM 12444|Rep:
Transketolase domain protein - Novosphingobium
aromaticivorans (strain DSM 12444)
Length = 327
Score = 81.0 bits (191), Expect = 2e-14
Identities = 45/150 (30%), Positives = 73/150 (48%)
Frame = +1
Query: 154 LASKPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPI 333
++S+ + A+ + EEM RD+ +F++G+ V G + + +GL ++G+ RV+D I
Sbjct: 1 MSSETMGYNAAMGLGLVEEMRRDDSIFIMGQGVVT-GGWFGMEKGLVAEFGNDRVLDCGI 59
Query: 334 TEXXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGP 513
E +KP+ +F++ A D I + AK YM VP+ V P
Sbjct: 60 AEAFEAGLAAGAAIAGMKPVINMGFGDFALIAGDEIYHKLAKWRYMHGLDVPMTAVIIFP 119
Query: 514 NGAASSVAAQHSQCFGAWYSHCPGLKVLMP 603
GA +HS C H PGLKV++P
Sbjct: 120 IGAMGGAGPEHSSCTEVLGMHFPGLKVVVP 149
>UniRef50_A4L2Q6 Cluster: E1 component beta subunit; n=16;
Bacilli|Rep: E1 component beta subunit - Lactobacillus
reuteri
Length = 325
Score = 81.0 bits (191), Expect = 2e-14
Identities = 41/140 (29%), Positives = 63/140 (45%)
Frame = +1
Query: 184 ALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXXXX 363
A+ + ID + D K V GE+V + G ++ T GL +KYG RV TP+ E
Sbjct: 9 AITEGIDIALAEDPKTLVFGEDVGKNGGVFRATNGLQEKYGVDRVFSTPLAESGILGMSM 68
Query: 364 XXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASSVAAQ 543
+P+ E F+ +A+D I ++ + GT PI R P G + A
Sbjct: 69 GLAVTGWRPVPEIQFMGFTFEAMDSIAAQMSRIRFQYNGTKHAPITIRTPYGGGTHTAEL 128
Query: 544 HSQCFGAWYSHCPGLKVLMP 603
H ++ PGL+V+ P
Sbjct: 129 HGDDLENFFVGIPGLRVVAP 148
>UniRef50_A7EW39 Cluster: Pyruvate dehydrogenase E1 component beta
subunit; n=16; Ascomycota|Rep: Pyruvate dehydrogenase E1
component beta subunit - Sclerotinia sclerotiorum 1980
Length = 403
Score = 80.2 bits (189), Expect = 4e-14
Identities = 44/150 (29%), Positives = 74/150 (49%), Gaps = 2/150 (1%)
Frame = +1
Query: 160 SKPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITE 339
+K + + ++N A+ + +DE V GE+V + G ++ + GL ++YG +RV +TP+ E
Sbjct: 76 TKRMNLFQSINDALSLALSKDETTMVFGEDVG-FGGVFRCSTGLAEQYGSERVFNTPLCE 134
Query: 340 XXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSA--GTVPVPIVFRGP 513
+K + E ++ A D ++N AAK Y G + R P
Sbjct: 135 QGIIGFAIGAAAEGMKAVAEIQFADYVYPAFDQLVNEAAKWRYRDGEYGRGLGGLTVRMP 194
Query: 514 NGAASSVAAQHSQCFGAWYSHCPGLKVLMP 603
GA A HSQ + ++H PGL+V+MP
Sbjct: 195 CGAVGHGALYHSQSPESLFTHIPGLRVIMP 224
>UniRef50_Q1IQR3 Cluster: Dehydrogenase, E1 component; n=1;
Acidobacteria bacterium Ellin345|Rep: Dehydrogenase, E1
component - Acidobacteria bacterium (strain Ellin345)
Length = 736
Score = 77.0 bits (181), Expect = 3e-13
Identities = 46/159 (28%), Positives = 75/159 (47%), Gaps = 15/159 (9%)
Frame = +1
Query: 172 TVRDALNQAIDEEMERDEKVFVLGEEVA-----QY---------DGAYKVTRGLWKKYGD 309
T+ D +N + +EM+RD ++ + GE+VA +Y G +K+T GL +YG
Sbjct: 397 TMADLINACLKDEMKRDPRIVIFGEDVADCSREEYLKQKQVKGKGGVFKLTSGLQMEYGA 456
Query: 310 KRVIDTPITEXXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVP 489
RV ++P+ E LKP+ E F++ A+ + N + S G
Sbjct: 457 DRVFNSPLAEANIVGRATGMAVRGLKPVVEIQFFDYIWPAMHQLRNELPVVRWRSNGAFS 516
Query: 490 VPIVFR-GPNGAASSVAAQHSQCFGAWYSHCPGLKVLMP 603
P V R G + A HSQC + ++H PG++V+ P
Sbjct: 517 SPAVIRVAIGGYLTGGAIYHSQCGESIFTHTPGMRVIFP 555
>UniRef50_A3SJ75 Cluster: 2-oxoisovalerate dehydrogenase beta
subunit; n=1; Roseovarius nubinhibens ISM|Rep:
2-oxoisovalerate dehydrogenase beta subunit -
Roseovarius nubinhibens ISM
Length = 746
Score = 76.2 bits (179), Expect = 6e-13
Identities = 43/142 (30%), Positives = 71/142 (50%), Gaps = 1/142 (0%)
Frame = +1
Query: 181 DALNQAIDEEMERDEKVFVLGEEVAQYDGAYK-VTRGLWKKYGDKRVIDTPITEXXXXXX 357
D +++ + ME+ + +FVLGE+V + G TRG+ +++ D R++ TPI E
Sbjct: 418 DVISEVMLRNMEKFDGLFVLGEDVHRLRGGTAGATRGIAERFPD-RLLGTPICENGFTGM 476
Query: 358 XXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASSVA 537
+P+ E M +FS+ A D + N AK +M G PVP+V R +
Sbjct: 477 ALGAALNGARPVVEIMYPDFSLVAADQLFNQIAKVRHMFGGDFPVPVVVRSRVTQGTGYG 536
Query: 538 AQHSQCFGAWYSHCPGLKVLMP 603
+QHS ++ PG +V+ P
Sbjct: 537 SQHSMDASGLFTLYPGWRVVAP 558
>UniRef50_Q2WB98 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
complex; n=1; Magnetospirillum magneticum AMB-1|Rep:
Pyruvate/2-oxoglutarate dehydrogenase complex -
Magnetospirillum magneticum (strain AMB-1 / ATCC 700264)
Length = 647
Score = 74.5 bits (175), Expect = 2e-12
Identities = 45/138 (32%), Positives = 63/138 (45%), Gaps = 1/138 (0%)
Frame = +1
Query: 187 LNQAIDEEMERDEKVFVLGEEVAQ-YDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXXXX 363
+ +D M D+++ +LGE++ Y GA+KVT GL Y RV +TPI+E
Sbjct: 326 IRAGLDAAMAADDRLLLLGEDICSPYGGAFKVTSGLSDSYPG-RVFNTPISEAGLVGVGA 384
Query: 364 XXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASSVAAQ 543
+ + E M +F D +IN AAK M V VP++ R P G
Sbjct: 385 GLALAGRRVVAEIMFGDFLTLVADQLINHAAKFTQMYGEDVEVPLLVRTPMGGRRGYGPT 444
Query: 544 HSQCFGAWYSHCPGLKVL 597
HSQ + PGL VL
Sbjct: 445 HSQSLETHFFGVPGLTVL 462
>UniRef50_Q9K3H1 Cluster: Putative pyruvate dehydrogenase beta
subunit; n=1; Streptomyces coelicolor|Rep: Putative
pyruvate dehydrogenase beta subunit - Streptomyces
coelicolor
Length = 337
Score = 71.3 bits (167), Expect = 2e-11
Identities = 43/139 (30%), Positives = 67/139 (48%), Gaps = 1/139 (0%)
Frame = +1
Query: 175 VRDALNQAIDEEMERDEKVFVLGEEVAQ-YDGAYKVTRGLWKKYGDKRVIDTPITEXXXX 351
V + LN A+ + +++GE+VA Y GA+KVTRGL ++ D RV+ +P++E
Sbjct: 7 VAENLNSALHHLLGAHPGTYLIGEDVADPYGGAFKVTRGLSDRFPD-RVLSSPLSEGGIA 65
Query: 352 XXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASS 531
+ + E M +F+ A D ++N AAK+ M VP+ +V R P G
Sbjct: 66 GVGAGLALAGNRSVVEMMFSDFAALAFDPLLNFAAKSVSMYGRRVPMSMVVRCPTGGNRG 125
Query: 532 VAAQHSQCFGAWYSHCPGL 588
HSQ + P L
Sbjct: 126 YGPTHSQSLQKHFLGIPSL 144
>UniRef50_Q8YDW3 Cluster: 2-OXOISOVALERATE DEHYDROGENASE BETA
SUBUNIT; n=10; Bacteria|Rep: 2-OXOISOVALERATE
DEHYDROGENASE BETA SUBUNIT - Brucella melitensis
Length = 729
Score = 70.1 bits (164), Expect = 4e-11
Identities = 44/143 (30%), Positives = 65/143 (45%), Gaps = 2/143 (1%)
Frame = +1
Query: 181 DALNQAIDEEMERDEKVFVLGEEVAQYDGAYK-VTRGLWKKYGDKRVIDTPITEXXXXXX 357
D + + ME DE+V VLGE+V + G TRGL Y D RV+ TPI+E
Sbjct: 403 DTVADVMARRMETDERVVVLGEDVHRLKGGTNGATRGLSADYPD-RVLGTPISENAFTGI 461
Query: 358 XXXXXXXX-LKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASSV 534
+ P+ EFM +F A D + N K +M G +P+V R +
Sbjct: 462 AGGMAADGRVLPVIEFMYPDFMWVAADQVFNQIGKARHMFGGDSDMPVVLRTKVAMGTGY 521
Query: 535 AAQHSQCFGAWYSHCPGLKVLMP 603
+QHS ++ PG +++ P
Sbjct: 522 GSQHSMDPAGIFATAPGWRIVAP 544
>UniRef50_A2TU24 Cluster: (Pyruvate) Oxoisovalerate Dehydrogenase
Alpha and Beta Fusion; n=6; cellular organisms|Rep:
(Pyruvate) Oxoisovalerate Dehydrogenase Alpha and Beta
Fusion - Dokdonia donghaensis MED134
Length = 693
Score = 68.9 bits (161), Expect = 9e-11
Identities = 39/146 (26%), Positives = 68/146 (46%), Gaps = 1/146 (0%)
Frame = +1
Query: 169 VTVRDALNQAIDEEMERDEKVFVLGEEVA-QYDGAYKVTRGLWKKYGDKRVIDTPITEXX 345
V + D A++E M + + + G++V + G ++ L +K+GD RV +TPI E
Sbjct: 357 VVMVDCALFAVEELMRKHPECLMYGQDVGGRLGGVFREAATLAQKFGDNRVFNTPIQEAF 416
Query: 346 XXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAA 525
LKPI E ++ ++ + +++ Y+S G PV ++ R P GA
Sbjct: 417 IVGSTVGMSAVGLKPIVEVQFADYIWPGLNQLFTEVSRSCYLSNGKWPVSMILRVPIGAY 476
Query: 526 SSVAAQHSQCFGAWYSHCPGLKVLMP 603
S HS + ++ GLK+ P
Sbjct: 477 GSGGPYHSSSVESVVTNIRGLKIAYP 502
>UniRef50_Q00TN9 Cluster: Pyruvate dehydrogenase E1 component beta;
n=3; Ostreococcus|Rep: Pyruvate dehydrogenase E1
component beta - Ostreococcus tauri
Length = 835
Score = 67.3 bits (157), Expect = 3e-10
Identities = 45/153 (29%), Positives = 71/153 (46%), Gaps = 4/153 (2%)
Frame = +1
Query: 148 KALASKP--VTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVI 321
+A+ + P +++ DA+N AI EEM RD E++ Q +Y + + +G R
Sbjct: 496 RAMCTDPRGISIGDAVNLAILEEMLRDPTTVAHAEDL-QAGSSYNIPANTQQAFGTLRAA 554
Query: 322 DTPITEXXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIV 501
D I E +PI E M NF + + + +SA T+ + G +P+
Sbjct: 555 DEIIDEGHFMGKALGEAMNGYRPIVELMNANFGIYGMAEL-SSAGNTYATTGGQFKMPMT 613
Query: 502 FRGPNGAA--SSVAAQHSQCFGAWYSHCPGLKV 594
G G A S+ A+HSQ F A+ PGLK+
Sbjct: 614 VIGAGGTAPNQSLGAEHSQPFHAYIMGIPGLKI 646
>UniRef50_Q8YDG0 Cluster: 2-OXOISOVALERATE DEHYDROGENASE BETA
SUBUNIT; n=3; Brucella|Rep: 2-OXOISOVALERATE
DEHYDROGENASE BETA SUBUNIT - Brucella melitensis
Length = 725
Score = 65.7 bits (153), Expect = 8e-10
Identities = 42/141 (29%), Positives = 63/141 (44%), Gaps = 1/141 (0%)
Frame = +1
Query: 184 ALNQAIDEEMERDEKVFVLGEEVAQYDGAYK-VTRGLWKKYGDKRVIDTPITEXXXXXXX 360
A + + ME+D + V+GE+V ++ G TR + + D RV+ PI E
Sbjct: 407 AASDVLGRAMEKDPTIIVIGEDVHRFAGGVSGFTRNALELFPD-RVLAMPIAENGFTGVV 465
Query: 361 XXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASSVAA 540
L+P+ E M +F A D I N +K +M PVPIV R + +
Sbjct: 466 LGAALRGLRPVVEIMFGDFCFVAADQIANGISKVRHMFGDGFPVPIVMRVRVSPHTGYGS 525
Query: 541 QHSQCFGAWYSHCPGLKVLMP 603
QHS A + PG +V+ P
Sbjct: 526 QHSGDPSALFGMFPGWRVVSP 546
>UniRef50_Q7N5R1 Cluster: Similar to 3-methyl-2-oxobutanoate
dehydrogenase; n=1; Photorhabdus luminescens subsp.
laumondii|Rep: Similar to 3-methyl-2-oxobutanoate
dehydrogenase - Photorhabdus luminescens subsp.
laumondii
Length = 665
Score = 64.9 bits (151), Expect = 1e-09
Identities = 39/142 (27%), Positives = 63/142 (44%), Gaps = 2/142 (1%)
Frame = +1
Query: 184 ALNQAIDEEMERDEKVFVLGEEVAQ-YDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXXX 360
A+NQ +DE + + V + GE++ G + TRGL +Y D RVI+ P++E
Sbjct: 348 AVNQVLDEALSQHPNVLIFGEDIEDPKGGVFGFTRGLSTRYPD-RVINAPLSEATIIGSS 406
Query: 361 XXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGA-ASSVA 537
+PI E +F ++ + + + + G P+V P GA
Sbjct: 407 VGLSASGWRPIVELQFIDFVGLGLNQLQSQLGTLSWRTVGKWRCPVVIYAPYGAYLPGGG 466
Query: 538 AQHSQCFGAWYSHCPGLKVLMP 603
HSQ +H PG+ VL+P
Sbjct: 467 IWHSQSSDGILAHIPGINVLVP 488
>UniRef50_UPI000038D520 Cluster: COG0022: Pyruvate/2-oxoglutarate
dehydrogenase complex, dehydrogenase (E1) component,
eukaryotic type, beta subunit; n=1; Nostoc punctiforme
PCC 73102|Rep: COG0022: Pyruvate/2-oxoglutarate
dehydrogenase complex, dehydrogenase (E1) component,
eukaryotic type, beta subunit - Nostoc punctiforme PCC
73102
Length = 343
Score = 64.5 bits (150), Expect = 2e-09
Identities = 43/139 (30%), Positives = 64/139 (46%), Gaps = 1/139 (0%)
Frame = +1
Query: 175 VRDALNQAIDEEMERDEKVFVLGEEVAQ-YDGAYKVTRGLWKKYGDKRVIDTPITEXXXX 351
V + LN+A+ D +VF++GE++ Y GA+KV +GL Y D RV+ TPI+E
Sbjct: 11 VVENLNRALHHIFAVDPQVFLIGEDILDPYGGAFKVGKGLSSNYPD-RVLTTPISEEAIV 69
Query: 352 XXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASS 531
KPI E M +F D I+N A+K+ M + + ++ R G
Sbjct: 70 GIGGGLALCGNKPIIEIMFGDFIALGFDQILNFASKSVSMYGTKLDLNMIVRCAVGGNRG 129
Query: 532 VAAQHSQCFGAWYSHCPGL 588
HSQ + P L
Sbjct: 130 YGPTHSQSLQKHFVGIPNL 148
>UniRef50_Q748I3 Cluster: Dehydrogenase, E1 component, alpha and
beta subunits; n=1; Geobacter sulfurreducens|Rep:
Dehydrogenase, E1 component, alpha and beta subunits -
Geobacter sulfurreducens
Length = 652
Score = 64.5 bits (150), Expect = 2e-09
Identities = 37/139 (26%), Positives = 63/139 (45%), Gaps = 1/139 (0%)
Frame = +1
Query: 184 ALNQAIDEEMERDEKVFVLGEEV-AQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXXX 360
++N ++ +E + K ++GE++ A Y GA+K T+ L + RV +TPI+E
Sbjct: 330 SINLSLQSLLENNSKAVIIGEDIEAPYGGAFKATKDLSTLFPG-RVKNTPISEGAITGVG 388
Query: 361 XXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASSVAA 540
P+ E M +F D ++ A K M + VP++ R P G
Sbjct: 389 IGLALSGFLPVVEIMFGDFMTLTFDQLLQHAGKFCEMYGKDLDVPLIIRTPMGGRRGYGP 448
Query: 541 QHSQCFGAWYSHCPGLKVL 597
HSQ ++ P L+V+
Sbjct: 449 THSQSLEKFFLGIPNLEVI 467
>UniRef50_A3BGZ8 Cluster: Putative uncharacterized protein; n=2;
Oryza sativa|Rep: Putative uncharacterized protein -
Oryza sativa subsp. japonica (Rice)
Length = 391
Score = 63.7 bits (148), Expect = 3e-09
Identities = 48/171 (28%), Positives = 72/171 (42%), Gaps = 22/171 (12%)
Frame = +1
Query: 157 ASKPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPIT 336
A K V + A+NQA+ ++ D + +V GE+V + G ++ T GL ++G RV +TP+
Sbjct: 46 AGKEVNLFTAINQALHIALDTDPRSYVFGEDVG-FGGVFRCTTGLADRFGRNRVFNTPLC 104
Query: 337 EXXXXXXXXXXXXXXLKPICEFMTFNFSMQAID---------------------HIINSA 453
E + I E ++ A D I+N A
Sbjct: 105 EQGIAGFAVGLAAMGNRAIAEIQFADYIFPAFDQACLRLDQCFVPTYLYIQLLVQIVNEA 164
Query: 454 AKTFYMSAGTVPV-PIVFRGPNGAASSVAAQHSQCFGAWYSHCPGLKVLMP 603
AK Y S + R P GA HSQ A++ H PGLKV++P
Sbjct: 165 AKFRYRSGNEFNCGGLTIRSPYGAVGHGGHYHSQSPEAFFCHVPGLKVIIP 215
>UniRef50_A3PXW7 Cluster: Transketolase domain protein; n=4;
Mycobacterium|Rep: Transketolase domain protein -
Mycobacterium sp. (strain JLS)
Length = 721
Score = 59.7 bits (138), Expect = 5e-08
Identities = 37/113 (32%), Positives = 51/113 (45%)
Frame = +1
Query: 169 VTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXX 348
VTV A+N+A+ + + + V GE+VA+ G Y VTRGL +K G RV DT + E
Sbjct: 386 VTVAQAVNRALADALAHHPEALVFGEDVARKGGVYGVTRGLQQKAGPARVFDTLLDEQAI 445
Query: 349 XXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFR 507
L PI E + A D I AA + + P+V R
Sbjct: 446 LGLALGAGVSGLLPIPEIQYLAYFHNAADQIRGEAATLQFFADRQYRNPMVVR 498
>UniRef50_A6FZ18 Cluster: 2-oxoisovalerate dehydrogenase, E1
component, alpha and beta subunit; n=1; Plesiocystis
pacifica SIR-1|Rep: 2-oxoisovalerate dehydrogenase, E1
component, alpha and beta subunit - Plesiocystis
pacifica SIR-1
Length = 757
Score = 58.8 bits (136), Expect = 9e-08
Identities = 34/146 (23%), Positives = 66/146 (45%), Gaps = 1/146 (0%)
Frame = +1
Query: 169 VTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITE-XX 345
+++ A+ A+ + +E + ++ G++VA+ G + T+GLW+++ +V D PI E
Sbjct: 374 ISLNGAIRAAMRDILESNPMAWIYGQDVAERGGVMQATKGLWERF-PSQVRDAPINEPLI 432
Query: 346 XXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAA 525
+ E ++S+ + H + + S GTV ++ R P
Sbjct: 433 LGTAVGYAMHEGATALPEIQFSDYSLNTL-HWLVHLGNLLWTSNGTVKANVIVRLPVEPL 491
Query: 526 SSVAAQHSQCFGAWYSHCPGLKVLMP 603
+ HS C +Y+ PGL +L P
Sbjct: 492 HGGSVYHSMCMEGFYAAIPGLTILAP 517
>UniRef50_A6W004 Cluster: Transketolase domain protein; n=6;
Proteobacteria|Rep: Transketolase domain protein -
Marinomonas sp. MWYL1
Length = 701
Score = 57.2 bits (132), Expect = 3e-07
Identities = 36/140 (25%), Positives = 61/140 (43%)
Frame = +1
Query: 184 ALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXXXX 363
A+ + +D E+ + KV V GE+V G + T GL +K+G RV DT ++E
Sbjct: 386 AIRKTLDYELATNPKVMVFGEDVGPKGGVHGATLGLNEKFGGDRVFDTSLSEEGIIGRSV 445
Query: 364 XXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASSVAAQ 543
L P+ E ++ A + + ++ + + P+V R P G A
Sbjct: 446 GLALSGLMPVPEIQFRKYAEPAAEQLSDTGIMR-WRTNNQFAAPMVVRIPGGFARRGDPW 504
Query: 544 HSQCFGAWYSHCPGLKVLMP 603
HS ++H G ++ MP
Sbjct: 505 HSMSDEVEWAHKVGWQLAMP 524
>UniRef50_A4F1Y5 Cluster: Branched-chain alpha-keto acid
decarboxylase; n=1; Streptomyces virginiae|Rep:
Branched-chain alpha-keto acid decarboxylase -
Streptomyces virginiae
Length = 677
Score = 56.8 bits (131), Expect = 4e-07
Identities = 35/146 (23%), Positives = 67/146 (45%), Gaps = 2/146 (1%)
Frame = +1
Query: 172 TVRDALNQAIDEEMERDEKVFVLGEEVAQ-YDGAYKVTRGLWKKYGDKRVIDTPITEXXX 348
T+ +A+N+A+ +E D + + GE++ G + T+GL G R+ ++P+ E
Sbjct: 357 TMVEAVNRALRTGLENDPTLVLFGEDIEDPKGGVFGFTKGLGTLAGP-RMTNSPLAEATI 415
Query: 349 XXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGP-NGAA 525
++P+ E +F+ A + I + + +A P+V P G
Sbjct: 416 VGAAVGLAAAGMRPVVELQFVDFAGPAWNQIASQLTTLRWRTASAWRCPVVIYAPWGGYL 475
Query: 526 SSVAAQHSQCFGAWYSHCPGLKVLMP 603
HSQ + ++H PGL+V++P
Sbjct: 476 PGGGIWHSQSNESLFTHLPGLRVVVP 501
>UniRef50_A1GCL6 Cluster: Transketolase-like; n=2; Salinispora|Rep:
Transketolase-like - Salinispora arenicola CNS205
Length = 805
Score = 56.8 bits (131), Expect = 4e-07
Identities = 31/114 (27%), Positives = 52/114 (45%)
Frame = +1
Query: 166 PVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXX 345
P+T+ ++N A+ + + ++ V GE+V G Y VT+GL +++G RV DT + E
Sbjct: 464 PLTLAQSINAALADGLLEHPRMAVFGEDVGAKGGVYGVTKGLRERFGAARVFDTLLDETS 523
Query: 346 XXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFR 507
+ P+ E + A D + AA + S G P+V R
Sbjct: 524 ILGLGLGAGLAGMLPVPEIQYLGYLHNAEDQLRGEAATMQFFSQGAYRNPMVVR 577
>UniRef50_Q7NLM8 Cluster: Gll1094 protein; n=1; Gloeobacter
violaceus|Rep: Gll1094 protein - Gloeobacter violaceus
Length = 481
Score = 56.4 bits (130), Expect = 5e-07
Identities = 33/142 (23%), Positives = 63/142 (44%), Gaps = 2/142 (1%)
Frame = +1
Query: 163 KPVTVRDALNQAIDEEMERDEKVFVLGEEVAQ-YDGAYKVTRGLWKKYGDKRVIDTPITE 339
+ T+ A+NQ + E ++ ++ + G+++ G + T+GL ++ +RV ++P+ E
Sbjct: 333 RTTTMVAAINQTLREALQLYPQMIMFGQDIEDPKGGVFGFTKGLSSQFS-QRVTNSPLAE 391
Query: 340 XXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNG 519
KP+ E +F A + ++ A + S G P+V P G
Sbjct: 392 ATIVGVAAGLAATGYKPVFELQFIDFITPAFNQLVQQIATLRWRSQGDWSCPMVLYAPYG 451
Query: 520 A-ASSVAAQHSQCFGAWYSHCP 582
A + HSQ W++H P
Sbjct: 452 AYLPGGSTWHSQSNEGWWTHIP 473
>UniRef50_Q7V0M6 Cluster: Dehydrogenase E1 component beta subunit;
n=1; Prochlorococcus marinus subsp. pastoris str.
CCMP1986|Rep: Dehydrogenase E1 component beta subunit -
Prochlorococcus marinus subsp. pastoris (strain CCMP
1378 / MED4)
Length = 309
Score = 54.8 bits (126), Expect = 2e-06
Identities = 37/141 (26%), Positives = 59/141 (41%)
Frame = +1
Query: 181 DALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXXX 360
+ + + +E E ++ LGE+V + GL +KYGDK++ID PI+E
Sbjct: 5 EKFREELFKEFESNKDAIYLGEDVRNAHRGIAI--GLHEKYGDKQIIDMPISESAFTGLA 62
Query: 361 XXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASSVAA 540
K E+ +D I N A K M + + +++ P G +A
Sbjct: 63 LGLAISKKKVFVEYNFAGLVYLGLDQIFNQAHKYNEMLNTNLNLDLIYILPTGTRGGLAG 122
Query: 541 QHSQCFGAWYSHCPGLKVLMP 603
HS A SH G++ MP
Sbjct: 123 HHSDNPYAILSHL-GIQSFMP 142
>UniRef50_A4BZ87 Cluster: Acetoin dehydrogenase (TPP-dependent) beta
chain; n=20; cellular organisms|Rep: Acetoin
dehydrogenase (TPP-dependent) beta chain - Polaribacter
irgensii 23-P
Length = 817
Score = 52.0 bits (119), Expect = 1e-05
Identities = 35/145 (24%), Positives = 58/145 (40%)
Frame = +1
Query: 169 VTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXX 348
V R + D +++ +V + GE+ + GL +KYGD RV DT I E
Sbjct: 483 VDARVVMRDNFDALLKKHPEVIIFGEDAGFIGDVNQGLEGLQEKYGDIRVSDTGIREATI 542
Query: 349 XXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAAS 528
L+PI E ++ + A+ + + A Y S G P++ R
Sbjct: 543 IGQGIGLAMRGLRPIAEIQYLDYLLYALQIMSDDLATLHYRSFGKQKAPLIIRTRGHRLE 602
Query: 529 SVAAQHSQCFGAWYSHCPGLKVLMP 603
+ S G ++ G+ VL+P
Sbjct: 603 GIWHAGSP-MGGIINNIRGMHVLVP 626
>UniRef50_Q5LVW0 Cluster: Dehydrogenase/transketolase family
protein; n=23; Proteobacteria|Rep:
Dehydrogenase/transketolase family protein -
Silicibacter pomeroyi
Length = 740
Score = 49.2 bits (112), Expect = 8e-05
Identities = 32/125 (25%), Positives = 52/125 (41%)
Frame = +1
Query: 133 SFATSKALASKPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDK 312
+F +P + +N A+ + M ++ +GE+V + G Y VT+ L +++G
Sbjct: 392 TFGGDMRAMDEPQPMSRLINWALTDLMLEHGEIVCMGEDVGRKGGVYGVTQKLQQRFGPD 451
Query: 313 RVIDTPITEXXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPV 492
R+IDT + E PI E + A D I AA + S G
Sbjct: 452 RMIDTLLDEQSILGLAIGMGHNGFLPIPEIQFLAYLHNAEDQIRGEAATLPFFSNGQFTN 511
Query: 493 PIVFR 507
P+V R
Sbjct: 512 PMVLR 516
>UniRef50_Q11G19 Cluster: Transketolase-like; n=2;
Proteobacteria|Rep: Transketolase-like - Mesorhizobium
sp. (strain BNC1)
Length = 323
Score = 48.0 bits (109), Expect = 2e-04
Identities = 37/142 (26%), Positives = 60/142 (42%), Gaps = 5/142 (3%)
Frame = +1
Query: 193 QAIDEEMERDEK---VFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXXXX 363
+A+ EM D +F L VA G ++ L K++G RV++T I E
Sbjct: 12 EAVQHEMLEDPNMVWIFELTPPVASNPG--RLVINLEKQFGRNRVVNTGIDENWMASATL 69
Query: 364 XXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVF-RGPNGAASSVAA 540
+ ++ + + I N A K +M+ G +P+VF G A
Sbjct: 70 GAGLAGSRA-ATYVPYQGACMPFQVIQNHAGKLRHMTGGKASMPVVFIMEMTGQTPGFAG 128
Query: 541 QHSQC-FGAWYSHCPGLKVLMP 603
QHS +Y+H PG+K ++P
Sbjct: 129 QHSDYEIDTYYAHIPGVKTVIP 150
>UniRef50_A2C5U9 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
complex, dehydrogenase (E1) component, eukaryotic type,
beta subunit; n=1; Prochlorococcus marinus str. MIT
9303|Rep: Pyruvate/2-oxoglutarate dehydrogenase complex,
dehydrogenase (E1) component, eukaryotic type, beta
subunit - Prochlorococcus marinus (strain MIT 9303)
Length = 359
Score = 48.0 bits (109), Expect = 2e-04
Identities = 29/114 (25%), Positives = 46/114 (40%)
Frame = +1
Query: 262 DGAYKVTRGLWKKYGDKRVIDTPITEXXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHI 441
DG Y L + + + P +E + I F F++ A++
Sbjct: 40 DGFYGTIAELSTHFSSQ-CYELPCSENASVGLAISASAYEVTTILCFQRVEFALLALEQF 98
Query: 442 INSAAKTFYMSAGTVPVPIVFRGPNGAASSVAAQHSQCFGAWYSHCPGLKVLMP 603
IN+AAK +++ G P P +FR G HSQ ++ P + VLMP
Sbjct: 99 INNAAKNNFLAGGRRPNPCLFRFVIGRGWGQGPSHSQSLETIFAQIPNINVLMP 152
>UniRef50_Q50851 Cluster: Branched-chain keto acid dehydrogenase E1
beta subunit; n=5; Deltaproteobacteria|Rep:
Branched-chain keto acid dehydrogenase E1 beta subunit -
Myxococcus xanthus
Length = 352
Score = 46.4 bits (105), Expect = 5e-04
Identities = 33/124 (26%), Positives = 54/124 (43%), Gaps = 1/124 (0%)
Frame = +1
Query: 235 VLGEEV-AQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXXXXXXXXXXLKPICEFMTF 411
+ GE+V A G + T+GL K ++P+ E +P+ E
Sbjct: 24 IFGEDVGAPLGGVFTCTQGL------KTTWNSPLDERGIIGAAMGIAMAGGRPVAEIQFC 77
Query: 412 NFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASSVAAQHSQCFGAWYSHCPGLK 591
++ ID ++ A T + + G +P+V R P G+ + HS F A +H G K
Sbjct: 78 DYVYNTID-LLKLAGNTSWSTFGDWNLPMVVRTPVGSGIRGSIYHSHSFDATMTHIAGWK 136
Query: 592 VLMP 603
V+MP
Sbjct: 137 VVMP 140
>UniRef50_UPI0000D9ADA1 Cluster: PREDICTED: similar to
2-oxoisovalerate dehydrogenase beta subunit,
mitochondrial precursor (Branched-chain alpha-keto acid
dehydrogenase E1 component beta chain) (BCKDH E1-beta);
n=1; Macaca mulatta|Rep: PREDICTED: similar to
2-oxoisovalerate dehydrogenase beta subunit,
mitochondrial precursor (Branched-chain alpha-keto acid
dehydrogenase E1 component beta chain) (BCKDH E1-beta) -
Macaca mulatta
Length = 340
Score = 46.0 bits (104), Expect = 7e-04
Identities = 23/87 (26%), Positives = 39/87 (44%)
Frame = +1
Query: 184 ALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXXXX 363
++ A+D + +D + GE+VA + G ++ T GL KYG RV +TP+ E
Sbjct: 76 SVTSALDNSLAKDPTAVIFGEDVA-FGGVFRCTVGLRDKYGKDRVFNTPLCEQGIVGFGI 134
Query: 364 XXXXXXLKPICEFMTFNFSMQAIDHII 444
I E ++ A D ++
Sbjct: 135 GIAVTGATAIAEIQFADYIFPAFDQVV 161
>UniRef50_Q5AT21 Cluster: Putative uncharacterized protein; n=1;
Emericella nidulans|Rep: Putative uncharacterized
protein - Emericella nidulans (Aspergillus nidulans)
Length = 376
Score = 41.1 bits (92), Expect = 0.020
Identities = 25/74 (33%), Positives = 35/74 (47%)
Frame = +1
Query: 382 LKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASSVAAQHSQCFG 561
+KP+ E ++ A D I+N AAK Y T G A A HSQ
Sbjct: 135 MKPVAEIQFADYVFPAFDQIVNEAAKFRYREGAT----------GGNAGHGALYHSQSPE 184
Query: 562 AWYSHCPGLKVLMP 603
A ++H PGL+V++P
Sbjct: 185 ALFAHIPGLQVVIP 198
>UniRef50_UPI0000383A75 Cluster: COG0508: Pyruvate/2-oxoglutarate
dehydrogenase complex, dihydrolipoamide acyltransferase
(E2) component, and related enzymes; n=1;
Magnetospirillum magnetotacticum MS-1|Rep: COG0508:
Pyruvate/2-oxoglutarate dehydrogenase complex,
dihydrolipoamide acyltransferase (E2) component, and
related enzymes - Magnetospirillum magnetotacticum MS-1
Length = 188
Score = 38.3 bits (85), Expect = 0.14
Identities = 22/55 (40%), Positives = 28/55 (50%), Gaps = 1/55 (1%)
Frame = +1
Query: 148 KALAS-KPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGD 309
K AS K T+R+AL A+D EM D V + G Y GA + GLW+ D
Sbjct: 116 KVYASYKRQTIREALRDAMDREMRADPDVLLNGRGTGPYHGANRAA-GLWRNGAD 169
>UniRef50_UPI00015970BB Cluster: GabT1; n=1; Bacillus
amyloliquefaciens FZB42|Rep: GabT1 - Bacillus
amyloliquefaciens FZB42
Length = 425
Score = 35.9 bits (79), Expect = 0.75
Identities = 20/59 (33%), Positives = 33/59 (55%), Gaps = 1/59 (1%)
Frame = +1
Query: 154 LASKPVTVRDALNQAIDEE-MERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDT 327
+ +K +T D+L ++D+ MER E +++ +E +Y T L YG+K VIDT
Sbjct: 4 VGTKEITNPDSLYYSVDDVVMERGEGIYLYDQEGNEYIDCASATFNLNLGYGNKEVIDT 62
>UniRef50_Q2IY37 Cluster: Tyrosinase; n=1; Rhodopseudomonas
palustris HaA2|Rep: Tyrosinase - Rhodopseudomonas
palustris (strain HaA2)
Length = 416
Score = 34.3 bits (75), Expect = 2.3
Identities = 19/51 (37%), Positives = 27/51 (52%)
Frame = +1
Query: 139 ATSKALASKPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGL 291
A+ LASKPV VR N + ERD+ + LG A+ G Y++ R +
Sbjct: 102 ASGAPLASKPVMVRIRKNAVTLSQEERDDFLAALGTLNARGQGPYRIVRDM 152
>UniRef50_A6LE04 Cluster: Putative uncharacterized protein; n=2;
Parabacteroides|Rep: Putative uncharacterized protein -
Parabacteroides distasonis (strain ATCC 8503 / DSM 20701
/ NCTC11152)
Length = 334
Score = 34.3 bits (75), Expect = 2.3
Identities = 20/64 (31%), Positives = 30/64 (46%), Gaps = 1/64 (1%)
Frame = +1
Query: 124 SRRSFATSKALASKPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYK-VTRGLWKK 300
++ +F +A + VR + + + EK F L E Y G Y+ V RGLW+
Sbjct: 221 AQEAFTEDYLVAMRDSVVRRNVPGSFPNSYMKTEKRFELSYEPITYRGEYRGVLRGLWRM 280
Query: 301 YGDK 312
GDK
Sbjct: 281 EGDK 284
>UniRef50_Q8EVJ3 Cluster: Transposase for IS1202-like insertion
sequence element; n=7; Mycoplasma penetrans|Rep:
Transposase for IS1202-like insertion sequence element -
Mycoplasma penetrans
Length = 562
Score = 33.9 bits (74), Expect = 3.0
Identities = 17/40 (42%), Positives = 24/40 (60%)
Frame = +1
Query: 112 LTRLSRRSFATSKALASKPVTVRDALNQAIDEEMERDEKV 231
L ++ R+S ATSKA+ K R AL + D ER+EK+
Sbjct: 512 LEKIKRKSIATSKAIYQKNENTRIALERWSDSLKEREEKI 551
>UniRef50_Q2IQQ3 Cluster: Putative uncharacterized protein
precursor; n=1; Anaeromyxobacter dehalogenans 2CP-C|Rep:
Putative uncharacterized protein precursor -
Anaeromyxobacter dehalogenans (strain 2CP-C)
Length = 226
Score = 33.9 bits (74), Expect = 3.0
Identities = 23/75 (30%), Positives = 36/75 (48%)
Frame = -2
Query: 563 APKHWECCAATLEAAPLGPRNTIGTGTVPADI*KVLAAEFII*SIACIEKLKVMNSQIGL 384
AP+H E LE LGPR + V ++ + A+E +A + L + +
Sbjct: 110 APRHVE----VLETTSLGPRRALVLARVGDEVLLLGASEA---GLALLRALPAVPAPAAA 162
Query: 383 SPAKAAPTAIPANPA 339
+PA+A P +PA PA
Sbjct: 163 APAQAVPPPLPARPA 177
>UniRef50_Q4SZE5 Cluster: Chromosome undetermined SCAF11680, whole
genome shotgun sequence; n=1; Tetraodon
nigroviridis|Rep: Chromosome undetermined SCAF11680,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 462
Score = 33.5 bits (73), Expect = 4.0
Identities = 13/26 (50%), Positives = 14/26 (53%)
Frame = -2
Query: 563 APKHWECCAATLEAAPLGPRNTIGTG 486
AP HWE PLGPR +GTG
Sbjct: 287 APVHWEFSLEPAAGGPLGPRGPVGTG 312
>UniRef50_A6GB58 Cluster: Transketolase; n=1; Plesiocystis pacifica
SIR-1|Rep: Transketolase - Plesiocystis pacifica SIR-1
Length = 336
Score = 33.5 bits (73), Expect = 4.0
Identities = 27/137 (19%), Positives = 60/137 (43%), Gaps = 1/137 (0%)
Frame = +1
Query: 187 LNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDK-RVIDTPITEXXXXXXXX 363
L + + E + DE+ +LGE+V G ++R + + + R++ P+T
Sbjct: 7 LARLLVELLREDERRCLLGEDVGN-GGMLGLSRAVAEDEQLRARLMPAPLTVNAGVAHAG 65
Query: 364 XXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASSVAAQ 543
L+PI + + ++A+ + + + S +P++F PNG + +
Sbjct: 66 GLALAGLRPIVVLPSASALLEALP-ALRELGRLPWRSGEQHDLPVLFVVPNGPGFGIGGE 124
Query: 544 HSQCFGAWYSHCPGLKV 594
++ A + PGL++
Sbjct: 125 AAESVEATLARVPGLEL 141
>UniRef50_Q89XT5 Cluster: Glyoxalase II; n=16;
Alphaproteobacteria|Rep: Glyoxalase II - Bradyrhizobium
japonicum
Length = 255
Score = 33.1 bits (72), Expect = 5.3
Identities = 15/29 (51%), Positives = 21/29 (72%)
Frame = -2
Query: 164 LEARAFDVAKLRRDNRVSIPRTAGDDFNA 78
L+ARA +VAKLR +N+ +IP GD+ A
Sbjct: 191 LQARAAEVAKLRAENKPTIPSLLGDEKRA 219
>UniRef50_A7SMP5 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 414
Score = 33.1 bits (72), Expect = 5.3
Identities = 14/33 (42%), Positives = 20/33 (60%)
Frame = +3
Query: 108 DAHSIIPSQFCHIESSGF*AGDCKRCFKSSDRR 206
D S+ CH++S GF G C +CF +SDR+
Sbjct: 40 DPSSLALHVACHVKSKGFLCGQCNKCF-TSDRQ 71
>UniRef50_A7AWY3 Cluster: Putative uncharacterized protein; n=1;
Babesia bovis|Rep: Putative uncharacterized protein -
Babesia bovis
Length = 1099
Score = 33.1 bits (72), Expect = 5.3
Identities = 19/85 (22%), Positives = 41/85 (48%), Gaps = 3/85 (3%)
Frame = +1
Query: 58 SDIIFKMALKSSPAVLGMLTRLSRRSFATSKALASKPVTVRDALN---QAIDEEMERDEK 228
+D + ++ P V GM L+ F ++ + P++V D ++ A+ ++ + K
Sbjct: 582 ADFSDPLRIRWIPKVSGMRPILNCNYFKVNRGSVTGPISVNDMMHIPFHALRAHVQTNPK 641
Query: 229 VFVLGEEVAQYDGAYKVTRGLWKKY 303
+ LG + Y GAY + W+++
Sbjct: 642 I--LGNSILGYSGAYISVKRWWRRF 664
>UniRef50_UPI0000DB7401 Cluster: PREDICTED: similar to zinc finger
protein 569; n=1; Apis mellifera|Rep: PREDICTED: similar
to zinc finger protein 569 - Apis mellifera
Length = 462
Score = 32.7 bits (71), Expect = 7.0
Identities = 25/78 (32%), Positives = 34/78 (43%), Gaps = 8/78 (10%)
Frame = +3
Query: 171 DCKRCFKSSDRRGDGERRESLRFG-----RGSR-SIRWCLQSYKGSMEEIW**KSY--RH 326
DC RC K RR D G +G R S++W Y G E K+Y R+
Sbjct: 147 DCNRCGKRFKRRKDLNYHIRHLCGIRGNYQGERYSVKWNNMGYVGYTSE----KNYLDRY 202
Query: 327 THHRGRIRRYSCWSCFCR 380
+H +R+ C +C CR
Sbjct: 203 RYHPNERKRFECLNCGCR 220
>UniRef50_Q0RU52 Cluster: Putative uncharacterized protein; n=1;
Frankia alni ACN14a|Rep: Putative uncharacterized
protein - Frankia alni (strain ACN14a)
Length = 467
Score = 32.7 bits (71), Expect = 7.0
Identities = 18/36 (50%), Positives = 22/36 (61%), Gaps = 1/36 (2%)
Frame = -2
Query: 377 AKAAPTAIP-ANPASVMGVSITLLSPYFFHRPLVTL 273
A AAP IP A PA V+G+S + FFHRP +L
Sbjct: 351 AAAAPGTIPVALPALVLGLSAVQVVSVFFHRPAQSL 386
>UniRef50_A0YMZ8 Cluster: Hemolysin-type calcium-binding region
protein; n=2; Oscillatoriales|Rep: Hemolysin-type
calcium-binding region protein - Lyngbya sp. PCC 8106
Length = 522
Score = 32.7 bits (71), Expect = 7.0
Identities = 17/41 (41%), Positives = 23/41 (56%), Gaps = 1/41 (2%)
Frame = +1
Query: 202 DEEMERDEKVFVLGEE-VAQYDGAYKVTRGLWKKYGDKRVI 321
DE + D+ +FVLG+E A YD Y+ L + DK VI
Sbjct: 427 DEPGDEDDDIFVLGDESQAYYDDGYEADYALITDFDDKDVI 467
>UniRef50_O74657 Cluster: Agglutinin-like protein 2 precursor; n=2;
Candida albicans|Rep: Agglutinin-like protein 2
precursor - Candida albicans (Yeast)
Length = 468
Score = 32.3 bits (70), Expect = 9.3
Identities = 21/56 (37%), Positives = 28/56 (50%)
Frame = +1
Query: 397 EFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASSVAAQHSQCFGA 564
EF TF+ + + + S+ K GTV +PI F G SSV + SQCF A
Sbjct: 103 EFTTFSSLKCTVSNTLTSSIKAL----GTVTLPISFN-VGGTGSSVDLESSQCFKA 153
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 604,009,726
Number of Sequences: 1657284
Number of extensions: 11816003
Number of successful extensions: 36865
Number of sequences better than 10.0: 115
Number of HSP's better than 10.0 without gapping: 35494
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 36812
length of database: 575,637,011
effective HSP length: 97
effective length of database: 414,880,463
effective search space used: 43562448615
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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