Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P14_F_L20
(666 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
Y12393-1|CAA73025.1| 281|Homo sapiens SRP1-like protein protein. 316 5e-86
U93240-1|AAC25605.1| 521|Homo sapiens importin alpha 3 protein. 316 5e-86
BC034493-1|AAH34493.1| 521|Homo sapiens karyopherin alpha 4 (im... 316 5e-86
BC028691-1|AAH28691.1| 521|Homo sapiens karyopherin alpha 4 (im... 316 5e-86
AB002533-1|BAA19546.1| 521|Homo sapiens Qip1 protein. 316 5e-86
Y12394-1|CAA73026.1| 521|Homo sapiens SRP1-like protein protein. 306 5e-83
D89618-1|BAA20378.1| 521|Homo sapiens karyopherin alhph 3 protein. 306 5e-83
BC024202-1|AAH24202.1| 521|Homo sapiens karyopherin alpha 3 (im... 306 5e-83
BC017355-1|AAH17355.1| 521|Homo sapiens karyopherin alpha 3 (im... 306 5e-83
AL136301-1|CAH71145.1| 521|Homo sapiens karyopherin alpha 3 (im... 306 5e-83
AL135901-3|CAI40716.1| 521|Homo sapiens karyopherin alpha 3 (im... 306 5e-83
AF034756-1|AAB87693.1| 521|Homo sapiens importin-alpha homolog ... 306 5e-83
AF005263-1|AAQ13404.1| 521|Homo sapiens importin alpha-3 subuni... 306 5e-83
BC035090-1|AAH35090.1| 521|Homo sapiens karyopherin alpha 3 (im... 302 6e-82
AK223480-1|BAD97200.1| 521|Homo sapiens karyopherin alpha 3 var... 300 2e-81
BT006665-1|AAP35311.1| 529|Homo sapiens karyopherin alpha 2 (RA... 216 7e-56
BC005978-1|AAH05978.1| 529|Homo sapiens karyopherin alpha 2 (RA... 216 7e-56
U28386-1|AAA69957.1| 529|Homo sapiens hSRP1alpha protein. 215 1e-55
U09559-1|AAA65700.1| 529|Homo sapiens Rch1 protein. 215 1e-55
BC067848-1|AAH67848.1| 529|Homo sapiens karyopherin alpha 2 (RA... 215 1e-55
BC053343-1|AAH53343.1| 529|Homo sapiens karyopherin alpha 2 (RA... 215 1e-55
AJ303086-1|CAC83080.1| 529|Homo sapiens karyopherin alpha 2 pro... 215 1e-55
BT009843-1|AAP88845.1| 536|Homo sapiens karyopherin alpha 6 (im... 203 5e-52
BC020520-1|AAH20520.1| 536|Homo sapiens karyopherin alpha 6 (im... 203 5e-52
AL445248-5|CAH71948.1| 536|Homo sapiens karyopherin alpha 6 (im... 203 5e-52
AL049795-3|CAI22056.1| 536|Homo sapiens karyopherin alpha 6 (im... 203 5e-52
AF060543-1|AAC15233.1| 536|Homo sapiens importin alpha 7 subuni... 203 5e-52
BC047409-1|AAH47409.1| 539|Homo sapiens karyopherin alpha 5 (im... 200 5e-51
AL132795-5|CAI20500.1| 539|Homo sapiens karyopherin alpha 5 (im... 200 5e-51
AF005361-1|AAC51868.1| 536|Homo sapiens importin alpha 6 protein. 200 5e-51
S75295-1|AAC60648.1| 538|Homo sapiens nucleoprotein interactor ... 196 4e-50
CR456743-1|CAG33024.1| 538|Homo sapiens KPNA1 protein. 196 4e-50
BT006959-1|AAP35605.1| 538|Homo sapiens karyopherin alpha 1 (im... 196 4e-50
BC090864-1|AAH90864.1| 538|Homo sapiens karyopherin alpha 1 (im... 196 4e-50
BC003009-1|AAH03009.1| 538|Homo sapiens karyopherin alpha 1 (im... 196 4e-50
BC002374-1|AAH02374.1| 538|Homo sapiens karyopherin alpha 1 (im... 196 4e-50
AL049795-1|CAI22054.1| 321|Homo sapiens karyopherin alpha 6 (im... 140 4e-33
AL135901-9|CAI40722.1| 90|Homo sapiens karyopherin alpha 3 (im... 97 5e-20
AL132795-7|CAI20502.1| 121|Homo sapiens karyopherin alpha 5 (im... 66 1e-10
CR533552-1|CAG38583.1| 509|Homo sapiens SPAG6 protein. 52 2e-06
AL513128-4|CAH72210.1| 509|Homo sapiens sperm associated antige... 52 2e-06
AL513128-3|CAH72209.1| 458|Homo sapiens sperm associated antige... 52 2e-06
AL158211-15|CAI15963.1| 509|Homo sapiens sperm associated antig... 52 2e-06
AL158211-14|CAI15962.1| 458|Homo sapiens sperm associated antig... 52 2e-06
AF079363-1|AAC32590.1| 509|Homo sapiens sperm flagellar protein... 52 2e-06
BC030585-1|AAH30585.1| 458|Homo sapiens sperm associated antige... 51 4e-06
U51269-1|AAC51202.1| 962|Homo sapiens armadillo repeat protein ... 50 1e-05
AL513128-1|CAH72207.1| 246|Homo sapiens sperm associated antige... 48 3e-05
AL158211-12|CAI15960.1| 246|Homo sapiens sperm associated antig... 48 3e-05
BC044907-1|AAH44907.1| 801|Homo sapiens ANKAR protein protein. 46 2e-04
AK126073-1|BAC86425.1| 1080|Homo sapiens protein ( Homo sapiens ... 46 2e-04
AJ549812-1|CAD71147.1| 1363|Homo sapiens hypothetical protein pr... 46 2e-04
X63465-1|CAA45067.1| 558|Homo sapiens smg GDS protein. 40 0.008
BC099845-1|AAH99845.1| 559|Homo sapiens RAP1GDS1 protein protein. 40 0.008
BC099708-1|AAH99708.1| 558|Homo sapiens RAP1GDS1 protein protein. 40 0.008
BC098334-1|AAH98334.1| 558|Homo sapiens RAP1GDS1 protein protein. 40 0.008
BC041699-1|AAH41699.1| 659|Homo sapiens armadillo repeat contai... 38 0.032
BC032661-1|AAH32661.1| 659|Homo sapiens armadillo repeat contai... 38 0.032
BC013424-1|AAH13424.1| 385|Homo sapiens armadillo repeat contai... 38 0.032
AK001721-1|BAA91861.1| 443|Homo sapiens protein ( Homo sapiens ... 34 0.40
X88824-1|CAA61294.1| 127|Homo sapiens immunoglobulin V(H) gene ... 32 1.6
BT007333-1|AAP35997.1| 610|Homo sapiens catenin (cadherin-assoc... 32 1.6
BC010501-1|AAH10501.2| 830|Homo sapiens CTNND1 protein protein. 32 1.6
AY505564-1|AAR84236.1| 941|Homo sapiens catenin (cadherin-assoc... 32 1.6
AF062344-1|AAC39829.1| 618|Homo sapiens p120 catenin isoform 4B... 32 1.6
AF062343-1|AAC39828.1| 933|Homo sapiens p120 catenin isoform 1A... 32 1.6
AF062342-1|AAC39827.1| 645|Homo sapiens p120 catenin isoform 4A... 32 1.6
AF062341-1|AAC39826.1| 968|Homo sapiens p120 catenin isoform 1A... 32 1.6
AF062340-1|AAC39825.1| 610|Homo sapiens p120 catenin isoform 4A... 32 1.6
AF062339-1|AAC39824.1| 933|Homo sapiens p120 catenin isoform 1A... 32 1.6
AF062338-1|AAC39823.1| 861|Homo sapiens p120 catenin isoform 3A... 32 1.6
AF062337-1|AAC39822.1| 838|Homo sapiens p120 catenin isoform 3A... 32 1.6
AF062336-1|AAC39821.1| 832|Homo sapiens p120 catenin isoform 3A... 32 1.6
AF062335-1|AAC39820.1| 832|Homo sapiens p120 catenin isoform 3A... 32 1.6
AF062334-1|AAC39819.1| 832|Homo sapiens p120 catenin isoform 3A... 32 1.6
AF062333-1|AAC39818.1| 610|Homo sapiens p120 catenin isoform 4A... 32 1.6
AF062332-1|AAC39817.1| 840|Homo sapiens p120 catenin isoform 3B... 32 1.6
AF062331-1|AAC39816.1| 879|Homo sapiens p120 catenin isoform 2A... 32 1.6
AF062330-1|AAC39815.1| 832|Homo sapiens p120 catenin isoform 3A... 32 1.6
AF062329-1|AAC39814.1| 879|Homo sapiens p120 catenin isoform 2A... 32 1.6
AF062328-1|AAC39813.1| 962|Homo sapiens p120 catenin isoform 1A... 32 1.6
AF062327-1|AAC39812.1| 879|Homo sapiens p120 catenin isoform 2A... 32 1.6
AF062326-1|AAC39811.1| 639|Homo sapiens p120 catenin isoform 4A... 32 1.6
AF062325-1|AAC39810.1| 887|Homo sapiens p120 catenin isoform 2B... 32 1.6
AF062324-1|AAC39809.1| 933|Homo sapiens p120 catenin isoform 1A... 32 1.6
AF062323-1|AAC39808.1| 867|Homo sapiens p120 catenin isoform 3A... 32 1.6
AF062322-1|AAC39807.1| 908|Homo sapiens p120 catenin isoform 2A... 32 1.6
AF062321-1|AAC39806.1| 939|Homo sapiens p120 catenin isoform 1A... 32 1.6
AF062320-1|AAC39805.1| 885|Homo sapiens p120 catenin isoform 2A... 32 1.6
AF062319-1|AAC39804.1| 914|Homo sapiens p120 catenin isoform 2A... 32 1.6
AF062318-1|AAC39803.1| 616|Homo sapiens p120 catenin isoform 4A... 32 1.6
AF062317-1|AAC39802.1| 941|Homo sapiens p120 catenin isoform 1B... 32 1.6
AB002382-1|BAA20838.2| 967|Homo sapiens KIAA0384 protein. 32 1.6
BC075795-1|AAH75795.1| 933|Homo sapiens CTNND1 protein protein. 31 2.8
Z19054-1|CAA79497.1| 781|Homo sapiens beta catenin protein. 30 6.5
Y07818-1|CAA69153.1| 570|Homo sapiens ULIP protein. 30 6.5
X87838-1|CAA61107.1| 781|Homo sapiens beta-catenin protein. 30 6.5
D78014-1|BAA11192.1| 570|Homo sapiens dihydropyrimidinase relat... 30 6.5
BC077077-1|AAH77077.1| 684|Homo sapiens DPYSL3 protein protein. 30 6.5
BC058926-1|AAH58926.1| 781|Homo sapiens catenin (cadherin-assoc... 30 6.5
BC039006-1|AAH39006.1| 570|Homo sapiens dihydropyrimidinase-lik... 30 6.5
AY463360-1|AAR18817.1| 781|Homo sapiens catenin (cadherin-assoc... 30 6.5
AB062292-1|BAB93475.1| 511|Homo sapiens catenin beta 1 protein. 30 6.5
>Y12393-1|CAA73025.1| 281|Homo sapiens SRP1-like protein protein.
Length = 281
Score = 316 bits (776), Expect = 5e-86
Identities = 150/192 (78%), Positives = 169/192 (88%)
Frame = +1
Query: 91 IPLLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWF 270
+PLLSH+EVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKI KEAVWF
Sbjct: 50 VPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKINKEAVWF 109
Query: 271 LSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALIN 450
LSNITAGN+QQVQAVIDA L+PMI+ L KG+F TQKEAAWA+SNL+ISG +DQVA LI
Sbjct: 110 LSNITAGNQQQVQAVIDANLVPMIIHLLDKGDFGTQKEAAWAISNLTISGRKDQVAYLIQ 169
Query: 451 CGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGDNAEQVANMIEECGGIDKIEDLQTHX 630
VIPPFCNLL+ KD QV+ VVLDGLSN+LKMA D AE + N+IEECGG++KIE LQ H
Sbjct: 170 QNVIPPFCNLLTVKDAQVVQVVLDGLSNILKMAEDEAETIGNLIEECGGLEKIEQLQNHE 229
Query: 631 KMEIYKMAYDII 666
+IYK+AY+II
Sbjct: 230 NEDIYKLAYEII 241
Score = 73.3 bits (172), Expect = 7e-13
Identities = 46/164 (28%), Positives = 85/164 (51%)
Frame = +1
Query: 97 LLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWFLS 276
L+ H +V + + A+ + +EQ Q+V++ + H LL+H + K+ A+ +
Sbjct: 10 LIHHTDVNILVDTVWALSYLTDAGNEQIQMVIDSGIVPHLVPLLSHQEVKVQTAALRAVG 69
Query: 277 NITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALINCG 456
NI G +Q Q V++ L A L+ + + KEA W +SN++ +G + QV A+I+
Sbjct: 70 NIVTGTDEQTQVVLNCDALSHFPALLTHPKEKINKEAVWFLSNIT-AGNQQQVQAVIDAN 128
Query: 457 VIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGDNAEQVANMIEE 588
++P +LL D +SN L ++G +QVA +I++
Sbjct: 129 LVPMIIHLLDKGDFGTQKEAAWAISN-LTISG-RKDQVAYLIQQ 170
Score = 50.0 bits (114), Expect = 7e-06
Identities = 24/36 (66%), Positives = 27/36 (75%)
Frame = +3
Query: 3 DTVWAISYLTXGGNEQIQMVIXSGIVTTLXSVVVAQ 110
DTVWA+SYLT GNEQIQMVI SGIV L ++ Q
Sbjct: 21 DTVWALSYLTDAGNEQIQMVIDSGIVPHLVPLLSHQ 56
>U93240-1|AAC25605.1| 521|Homo sapiens importin alpha 3 protein.
Length = 521
Score = 316 bits (776), Expect = 5e-86
Identities = 150/192 (78%), Positives = 169/192 (88%)
Frame = +1
Query: 91 IPLLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWF 270
+PLLSH+EVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKI KEAVWF
Sbjct: 290 VPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKINKEAVWF 349
Query: 271 LSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALIN 450
LSNITAGN+QQVQAVIDA L+PMI+ L KG+F TQKEAAWA+SNL+ISG +DQVA LI
Sbjct: 350 LSNITAGNQQQVQAVIDANLVPMIIHLLDKGDFGTQKEAAWAISNLTISGRKDQVAYLIQ 409
Query: 451 CGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGDNAEQVANMIEECGGIDKIEDLQTHX 630
VIPPFCNLL+ KD QV+ VVLDGLSN+LKMA D AE + N+IEECGG++KIE LQ H
Sbjct: 410 QNVIPPFCNLLTVKDAQVVQVVLDGLSNILKMAEDEAETIGNLIEECGGLEKIEQLQNHE 469
Query: 631 KMEIYKMAYDII 666
+IYK+AY+II
Sbjct: 470 NEDIYKLAYEII 481
Score = 73.3 bits (172), Expect = 7e-13
Identities = 46/164 (28%), Positives = 85/164 (51%)
Frame = +1
Query: 97 LLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWFLS 276
L+ H +V + + A+ + +EQ Q+V++ + H LL+H + K+ A+ +
Sbjct: 250 LIHHTDVNILVDTVWALSYLTDAGNEQIQMVIDSGIVPHLVPLLSHQEVKVQTAALRAVG 309
Query: 277 NITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALINCG 456
NI G +Q Q V++ L A L+ + + KEA W +SN++ +G + QV A+I+
Sbjct: 310 NIVTGTDEQTQVVLNCDALSHFPALLTHPKEKINKEAVWFLSNIT-AGNQQQVQAVIDAN 368
Query: 457 VIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGDNAEQVANMIEE 588
++P +LL D +SN L ++G +QVA +I++
Sbjct: 369 LVPMIIHLLDKGDFGTQKEAAWAISN-LTISG-RKDQVAYLIQQ 410
Score = 64.9 bits (151), Expect = 2e-10
Identities = 46/179 (25%), Positives = 84/179 (46%), Gaps = 1/179 (0%)
Frame = +1
Query: 121 VQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWFLSNITAGNKQ 300
+Q A A+ NI +GT EQTQ V+ +A+ F LL P + +C++AVW L NI Q
Sbjct: 131 LQFEAAWALTNIASGTSEQTQAVVQSNAVPLFLRLLHSPHQNVCEQAVWALGNIIGDGPQ 190
Query: 301 QVQAVIDAGLLPMIVANLSKG-EFQTQKEAAWAVSNLSISGTRDQVAALINCGVIPPFCN 477
VI G++ +++ +S + W + NL I ++P C
Sbjct: 191 CRDYVISLGVVKPLLSFISPSIPITFLRNVTWVMVNLCRHKDPPPPMETIQ-EILPALCV 249
Query: 478 LLSCKDTQVINVVLDGLSNMLKMAGDNAEQVANMIEECGGIDKIEDLQTHXKMEIYKMA 654
L+ D +N+++D + + + EQ+ M+ + G + + L +H ++++ A
Sbjct: 250 LIHHTD---VNILVDTVWALSYLTDAGNEQI-QMVIDSGIVPHLVPLLSHQEVKVQTAA 304
Score = 50.0 bits (114), Expect = 7e-06
Identities = 24/36 (66%), Positives = 27/36 (75%)
Frame = +3
Query: 3 DTVWAISYLTXGGNEQIQMVIXSGIVTTLXSVVVAQ 110
DTVWA+SYLT GNEQIQMVI SGIV L ++ Q
Sbjct: 261 DTVWALSYLTDAGNEQIQMVIDSGIVPHLVPLLSHQ 296
>BC034493-1|AAH34493.1| 521|Homo sapiens karyopherin alpha 4
(importin alpha 3) protein.
Length = 521
Score = 316 bits (776), Expect = 5e-86
Identities = 150/192 (78%), Positives = 169/192 (88%)
Frame = +1
Query: 91 IPLLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWF 270
+PLLSH+EVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKI KEAVWF
Sbjct: 290 VPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKINKEAVWF 349
Query: 271 LSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALIN 450
LSNITAGN+QQVQAVIDA L+PMI+ L KG+F TQKEAAWA+SNL+ISG +DQVA LI
Sbjct: 350 LSNITAGNQQQVQAVIDANLVPMIIHLLDKGDFGTQKEAAWAISNLTISGRKDQVAYLIQ 409
Query: 451 CGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGDNAEQVANMIEECGGIDKIEDLQTHX 630
VIPPFCNLL+ KD QV+ VVLDGLSN+LKMA D AE + N+IEECGG++KIE LQ H
Sbjct: 410 QNVIPPFCNLLTVKDAQVVQVVLDGLSNILKMAEDEAETIGNLIEECGGLEKIEQLQNHE 469
Query: 631 KMEIYKMAYDII 666
+IYK+AY+II
Sbjct: 470 NEDIYKLAYEII 481
Score = 73.3 bits (172), Expect = 7e-13
Identities = 46/164 (28%), Positives = 85/164 (51%)
Frame = +1
Query: 97 LLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWFLS 276
L+ H +V + + A+ + +EQ Q+V++ + H LL+H + K+ A+ +
Sbjct: 250 LIHHTDVNILVDTVWALSYLTDAGNEQIQMVIDSGIVPHLVPLLSHQEVKVQTAALRAVG 309
Query: 277 NITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALINCG 456
NI G +Q Q V++ L A L+ + + KEA W +SN++ +G + QV A+I+
Sbjct: 310 NIVTGTDEQTQVVLNCDALSHFPALLTHPKEKINKEAVWFLSNIT-AGNQQQVQAVIDAN 368
Query: 457 VIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGDNAEQVANMIEE 588
++P +LL D +SN L ++G +QVA +I++
Sbjct: 369 LVPMIIHLLDKGDFGTQKEAAWAISN-LTISG-RKDQVAYLIQQ 410
Score = 64.9 bits (151), Expect = 2e-10
Identities = 46/179 (25%), Positives = 84/179 (46%), Gaps = 1/179 (0%)
Frame = +1
Query: 121 VQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWFLSNITAGNKQ 300
+Q A A+ NI +GT EQTQ V+ +A+ F LL P + +C++AVW L NI Q
Sbjct: 131 LQFEAAWALTNIASGTSEQTQAVVQSNAVPLFLRLLHSPHQNVCEQAVWALGNIIGDGPQ 190
Query: 301 QVQAVIDAGLLPMIVANLSKG-EFQTQKEAAWAVSNLSISGTRDQVAALINCGVIPPFCN 477
VI G++ +++ +S + W + NL I ++P C
Sbjct: 191 CRDYVISLGVVKPLLSFISPSIPITFLRNVTWVMVNLCRHKDPPPPMETIQ-EILPALCV 249
Query: 478 LLSCKDTQVINVVLDGLSNMLKMAGDNAEQVANMIEECGGIDKIEDLQTHXKMEIYKMA 654
L+ D +N+++D + + + EQ+ M+ + G + + L +H ++++ A
Sbjct: 250 LIHHTD---VNILVDTVWALSYLTDAGNEQI-QMVIDSGIVPHLVPLLSHQEVKVQTAA 304
Score = 50.0 bits (114), Expect = 7e-06
Identities = 24/36 (66%), Positives = 27/36 (75%)
Frame = +3
Query: 3 DTVWAISYLTXGGNEQIQMVIXSGIVTTLXSVVVAQ 110
DTVWA+SYLT GNEQIQMVI SGIV L ++ Q
Sbjct: 261 DTVWALSYLTDAGNEQIQMVIDSGIVPHLVPLLSHQ 296
>BC028691-1|AAH28691.1| 521|Homo sapiens karyopherin alpha 4
(importin alpha 3) protein.
Length = 521
Score = 316 bits (776), Expect = 5e-86
Identities = 150/192 (78%), Positives = 169/192 (88%)
Frame = +1
Query: 91 IPLLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWF 270
+PLLSH+EVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKI KEAVWF
Sbjct: 290 VPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKINKEAVWF 349
Query: 271 LSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALIN 450
LSNITAGN+QQVQAVIDA L+PMI+ L KG+F TQKEAAWA+SNL+ISG +DQVA LI
Sbjct: 350 LSNITAGNQQQVQAVIDANLVPMIIHLLDKGDFGTQKEAAWAISNLTISGRKDQVAYLIQ 409
Query: 451 CGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGDNAEQVANMIEECGGIDKIEDLQTHX 630
VIPPFCNLL+ KD QV+ VVLDGLSN+LKMA D AE + N+IEECGG++KIE LQ H
Sbjct: 410 QNVIPPFCNLLTVKDAQVVQVVLDGLSNILKMAEDEAETIGNLIEECGGLEKIEQLQNHE 469
Query: 631 KMEIYKMAYDII 666
+IYK+AY+II
Sbjct: 470 NEDIYKLAYEII 481
Score = 73.3 bits (172), Expect = 7e-13
Identities = 46/164 (28%), Positives = 85/164 (51%)
Frame = +1
Query: 97 LLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWFLS 276
L+ H +V + + A+ + +EQ Q+V++ + H LL+H + K+ A+ +
Sbjct: 250 LIHHTDVNILVDTVWALSYLTDAGNEQIQMVIDSGIVPHLVPLLSHQEVKVQTAALRAVG 309
Query: 277 NITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALINCG 456
NI G +Q Q V++ L A L+ + + KEA W +SN++ +G + QV A+I+
Sbjct: 310 NIVTGTDEQTQVVLNCDALSHFPALLTHPKEKINKEAVWFLSNIT-AGNQQQVQAVIDAN 368
Query: 457 VIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGDNAEQVANMIEE 588
++P +LL D +SN L ++G +QVA +I++
Sbjct: 369 LVPMIIHLLDKGDFGTQKEAAWAISN-LTISG-RKDQVAYLIQQ 410
Score = 64.9 bits (151), Expect = 2e-10
Identities = 46/179 (25%), Positives = 84/179 (46%), Gaps = 1/179 (0%)
Frame = +1
Query: 121 VQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWFLSNITAGNKQ 300
+Q A A+ NI +GT EQTQ V+ +A+ F LL P + +C++AVW L NI Q
Sbjct: 131 LQFEAAWALTNIASGTSEQTQAVVQSNAVPLFLRLLHSPHQNVCEQAVWALGNIIGDGPQ 190
Query: 301 QVQAVIDAGLLPMIVANLSKG-EFQTQKEAAWAVSNLSISGTRDQVAALINCGVIPPFCN 477
VI G++ +++ +S + W + NL I ++P C
Sbjct: 191 CRDYVISLGVVKPLLSFISPSIPITFLRNVTWVMVNLCRHKDPPPPMETIQ-EILPALCV 249
Query: 478 LLSCKDTQVINVVLDGLSNMLKMAGDNAEQVANMIEECGGIDKIEDLQTHXKMEIYKMA 654
L+ D +N+++D + + + EQ+ M+ + G + + L +H ++++ A
Sbjct: 250 LIHHTD---VNILVDTVWALSYLTDAGNEQI-QMVIDSGIVPHLVPLLSHQEVKVQTAA 304
Score = 50.0 bits (114), Expect = 7e-06
Identities = 24/36 (66%), Positives = 27/36 (75%)
Frame = +3
Query: 3 DTVWAISYLTXGGNEQIQMVIXSGIVTTLXSVVVAQ 110
DTVWA+SYLT GNEQIQMVI SGIV L ++ Q
Sbjct: 261 DTVWALSYLTDAGNEQIQMVIDSGIVPHLVPLLSHQ 296
>AB002533-1|BAA19546.1| 521|Homo sapiens Qip1 protein.
Length = 521
Score = 316 bits (776), Expect = 5e-86
Identities = 150/192 (78%), Positives = 169/192 (88%)
Frame = +1
Query: 91 IPLLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWF 270
+PLLSH+EVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKI KEAVWF
Sbjct: 290 VPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKINKEAVWF 349
Query: 271 LSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALIN 450
LSNITAGN+QQVQAVIDA L+PMI+ L KG+F TQKEAAWA+SNL+ISG +DQVA LI
Sbjct: 350 LSNITAGNQQQVQAVIDANLVPMIIHLLDKGDFGTQKEAAWAISNLTISGRKDQVAYLIQ 409
Query: 451 CGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGDNAEQVANMIEECGGIDKIEDLQTHX 630
VIPPFCNLL+ KD QV+ VVLDGLSN+LKMA D AE + N+IEECGG++KIE LQ H
Sbjct: 410 QNVIPPFCNLLTVKDAQVVQVVLDGLSNILKMAEDEAETIGNLIEECGGLEKIEQLQNHE 469
Query: 631 KMEIYKMAYDII 666
+IYK+AY+II
Sbjct: 470 NEDIYKLAYEII 481
Score = 73.3 bits (172), Expect = 7e-13
Identities = 46/164 (28%), Positives = 85/164 (51%)
Frame = +1
Query: 97 LLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWFLS 276
L+ H +V + + A+ + +EQ Q+V++ + H LL+H + K+ A+ +
Sbjct: 250 LIHHTDVNILVDTVWALSYLTDAGNEQIQMVIDSGIVPHLVPLLSHQEVKVQTAALRAVG 309
Query: 277 NITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALINCG 456
NI G +Q Q V++ L A L+ + + KEA W +SN++ +G + QV A+I+
Sbjct: 310 NIVTGTDEQTQVVLNCDALSHFPALLTHPKEKINKEAVWFLSNIT-AGNQQQVQAVIDAN 368
Query: 457 VIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGDNAEQVANMIEE 588
++P +LL D +SN L ++G +QVA +I++
Sbjct: 369 LVPMIIHLLDKGDFGTQKEAAWAISN-LTISG-RKDQVAYLIQQ 410
Score = 64.9 bits (151), Expect = 2e-10
Identities = 46/179 (25%), Positives = 84/179 (46%), Gaps = 1/179 (0%)
Frame = +1
Query: 121 VQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWFLSNITAGNKQ 300
+Q A A+ NI +GT EQTQ V+ +A+ F LL P + +C++AVW L NI Q
Sbjct: 131 LQFEAAWALTNIASGTSEQTQAVVQSNAVPLFLRLLHSPHQNVCEQAVWALGNIIGDGPQ 190
Query: 301 QVQAVIDAGLLPMIVANLSKG-EFQTQKEAAWAVSNLSISGTRDQVAALINCGVIPPFCN 477
VI G++ +++ +S + W + NL I ++P C
Sbjct: 191 CRDYVISLGVVKPLLSFISPSIPITFLRNVTWVMVNLCRHKDPPPPMETIQ-EILPALCV 249
Query: 478 LLSCKDTQVINVVLDGLSNMLKMAGDNAEQVANMIEECGGIDKIEDLQTHXKMEIYKMA 654
L+ D +N+++D + + + EQ+ M+ + G + + L +H ++++ A
Sbjct: 250 LIHHTD---VNILVDTVWALSYLTDAGNEQI-QMVIDSGIVPHLVPLLSHQEVKVQTAA 304
Score = 50.0 bits (114), Expect = 7e-06
Identities = 24/36 (66%), Positives = 27/36 (75%)
Frame = +3
Query: 3 DTVWAISYLTXGGNEQIQMVIXSGIVTTLXSVVVAQ 110
DTVWA+SYLT GNEQIQMVI SGIV L ++ Q
Sbjct: 261 DTVWALSYLTDAGNEQIQMVIDSGIVPHLVPLLSHQ 296
>Y12394-1|CAA73026.1| 521|Homo sapiens SRP1-like protein protein.
Length = 521
Score = 306 bits (751), Expect = 5e-83
Identities = 144/192 (75%), Positives = 167/192 (86%)
Frame = +1
Query: 91 IPLLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWF 270
+PLLSH+EVKVQTAALRAVGNIVTGTDEQTQVVLNCD LSHFP LL+HPKEKI KEAVWF
Sbjct: 290 VPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWF 349
Query: 271 LSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALIN 450
LSNITAGN+QQVQAVIDAGL+PMI+ L+KG+F TQKEAAWA+SNL+ISG +DQV L+
Sbjct: 350 LSNITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAISNLTISGRKDQVEYLVQ 409
Query: 451 CGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGDNAEQVANMIEECGGIDKIEDLQTHX 630
VIPPFCNLLS KD+QV+ VVLDGL N+L MAGD A +A +IEECGG++KIE LQ H
Sbjct: 410 QNVIPPFCNLLSVKDSQVVQVVLDGLKNILIMAGDEASTIAEIIEECGGLEKIEVLQQHE 469
Query: 631 KMEIYKMAYDII 666
+IYK+A++II
Sbjct: 470 NEDIYKLAFEII 481
Score = 70.1 bits (164), Expect = 7e-12
Identities = 45/164 (27%), Positives = 85/164 (51%)
Frame = +1
Query: 97 LLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWFLS 276
L+ H +V + + A+ + G +EQ Q+V++ + LL+H + K+ A+ +
Sbjct: 250 LIYHTDVNIVVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVG 309
Query: 277 NITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALINCG 456
NI G +Q Q V++ +L LS + + KEA W +SN++ +G + QV A+I+ G
Sbjct: 310 NIVTGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWFLSNIT-AGNQQQVQAVIDAG 368
Query: 457 VIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGDNAEQVANMIEE 588
+IP + L+ D +SN L ++G +QV ++++
Sbjct: 369 LIPMIIHQLAKGDFGTQKEAAWAISN-LTISG-RKDQVEYLVQQ 410
Score = 64.9 bits (151), Expect = 2e-10
Identities = 45/179 (25%), Positives = 84/179 (46%), Gaps = 1/179 (0%)
Frame = +1
Query: 121 VQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWFLSNITAGNKQ 300
+Q A A+ NI +GT QTQ V+ +A+ F LL P + +C++AVW L NI Q
Sbjct: 131 LQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQNVCEQAVWALGNIIGDGPQ 190
Query: 301 QVQAVIDAGLLPMIVANLSKG-EFQTQKEAAWAVSNLSISGTRDQVAALINCGVIPPFCN 477
VI G++ +++ +S + W + NL + + ++P C
Sbjct: 191 CRDYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPPLETVQ-EILPALCV 249
Query: 478 LLSCKDTQVINVVLDGLSNMLKMAGDNAEQVANMIEECGGIDKIEDLQTHXKMEIYKMA 654
L+ D +N+V+D + + + EQ+ M+ + G + + L +H ++++ A
Sbjct: 250 LIYHTD---VNIVVDTVWALSYLTDGGNEQI-QMVIDSGVVPFLVPLLSHQEVKVQTAA 304
Score = 52.0 bits (119), Expect = 2e-06
Identities = 24/36 (66%), Positives = 28/36 (77%)
Frame = +3
Query: 3 DTVWAISYLTXGGNEQIQMVIXSGIVTTLXSVVVAQ 110
DTVWA+SYLT GGNEQIQMVI SG+V L ++ Q
Sbjct: 261 DTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQ 296
Score = 30.3 bits (65), Expect = 6.5
Identities = 10/26 (38%), Positives = 18/26 (69%)
Frame = +3
Query: 3 DTVWAISYLTXGGNEQIQMVIXSGIV 80
+ VW +S +T G +Q+Q VI +G++
Sbjct: 345 EAVWFLSNITAGNQQQVQAVIDAGLI 370
>D89618-1|BAA20378.1| 521|Homo sapiens karyopherin alhph 3 protein.
Length = 521
Score = 306 bits (751), Expect = 5e-83
Identities = 144/192 (75%), Positives = 167/192 (86%)
Frame = +1
Query: 91 IPLLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWF 270
+PLLSH+EVKVQTAALRAVGNIVTGTDEQTQVVLNCD LSHFP LL+HPKEKI KEAVWF
Sbjct: 290 VPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWF 349
Query: 271 LSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALIN 450
LSNITAGN+QQVQAVIDAGL+PMI+ L+KG+F TQKEAAWA+SNL+ISG +DQV L+
Sbjct: 350 LSNITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAISNLTISGRKDQVEYLVQ 409
Query: 451 CGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGDNAEQVANMIEECGGIDKIEDLQTHX 630
VIPPFCNLLS KD+QV+ VVLDGL N+L MAGD A +A +IEECGG++KIE LQ H
Sbjct: 410 QNVIPPFCNLLSVKDSQVVQVVLDGLKNILIMAGDEASTIAEIIEECGGLEKIEVLQQHE 469
Query: 631 KMEIYKMAYDII 666
+IYK+A++II
Sbjct: 470 NEDIYKLAFEII 481
Score = 69.7 bits (163), Expect = 9e-12
Identities = 44/164 (26%), Positives = 85/164 (51%)
Frame = +1
Query: 97 LLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWFLS 276
L+ H ++ + + A+ + G +EQ Q+V++ + LL+H + K+ A+ +
Sbjct: 250 LIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVG 309
Query: 277 NITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALINCG 456
NI G +Q Q V++ +L LS + + KEA W +SN++ +G + QV A+I+ G
Sbjct: 310 NIVTGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWFLSNIT-AGNQQQVQAVIDAG 368
Query: 457 VIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGDNAEQVANMIEE 588
+IP + L+ D +SN L ++G +QV ++++
Sbjct: 369 LIPMIIHQLAKGDFGTQKEAAWAISN-LTISG-RKDQVEYLVQQ 410
Score = 64.1 bits (149), Expect = 4e-10
Identities = 45/179 (25%), Positives = 84/179 (46%), Gaps = 1/179 (0%)
Frame = +1
Query: 121 VQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWFLSNITAGNKQ 300
+Q A A+ NI +GT QTQ V+ +A+ F LL P + +C++AVW L NI Q
Sbjct: 131 LQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQNVCEQAVWALGNIIGDGPQ 190
Query: 301 QVQAVIDAGLLPMIVANLSKG-EFQTQKEAAWAVSNLSISGTRDQVAALINCGVIPPFCN 477
VI G++ +++ +S + W + NL + + ++P C
Sbjct: 191 CRDYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQ-EILPALCV 249
Query: 478 LLSCKDTQVINVVLDGLSNMLKMAGDNAEQVANMIEECGGIDKIEDLQTHXKMEIYKMA 654
L+ D IN+++D + + + EQ+ M+ + G + + L +H ++++ A
Sbjct: 250 LIYHTD---INILVDTVWALSYLTDGGNEQI-QMVIDSGVVPFLVPLLSHQEVKVQTAA 304
Score = 52.0 bits (119), Expect = 2e-06
Identities = 24/36 (66%), Positives = 28/36 (77%)
Frame = +3
Query: 3 DTVWAISYLTXGGNEQIQMVIXSGIVTTLXSVVVAQ 110
DTVWA+SYLT GGNEQIQMVI SG+V L ++ Q
Sbjct: 261 DTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQ 296
Score = 30.3 bits (65), Expect = 6.5
Identities = 10/26 (38%), Positives = 18/26 (69%)
Frame = +3
Query: 3 DTVWAISYLTXGGNEQIQMVIXSGIV 80
+ VW +S +T G +Q+Q VI +G++
Sbjct: 345 EAVWFLSNITAGNQQQVQAVIDAGLI 370
>BC024202-1|AAH24202.1| 521|Homo sapiens karyopherin alpha 3
(importin alpha 4) protein.
Length = 521
Score = 306 bits (751), Expect = 5e-83
Identities = 144/192 (75%), Positives = 167/192 (86%)
Frame = +1
Query: 91 IPLLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWF 270
+PLLSH+EVKVQTAALRAVGNIVTGTDEQTQVVLNCD LSHFP LL+HPKEKI KEAVWF
Sbjct: 290 VPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWF 349
Query: 271 LSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALIN 450
LSNITAGN+QQVQAVIDAGL+PMI+ L+KG+F TQKEAAWA+SNL+ISG +DQV L+
Sbjct: 350 LSNITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAISNLTISGRKDQVEYLVQ 409
Query: 451 CGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGDNAEQVANMIEECGGIDKIEDLQTHX 630
VIPPFCNLLS KD+QV+ VVLDGL N+L MAGD A +A +IEECGG++KIE LQ H
Sbjct: 410 QNVIPPFCNLLSVKDSQVVQVVLDGLKNILIMAGDEASTIAEIIEECGGLEKIEVLQQHE 469
Query: 631 KMEIYKMAYDII 666
+IYK+A++II
Sbjct: 470 NEDIYKLAFEII 481
Score = 69.7 bits (163), Expect = 9e-12
Identities = 44/164 (26%), Positives = 85/164 (51%)
Frame = +1
Query: 97 LLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWFLS 276
L+ H ++ + + A+ + G +EQ Q+V++ + LL+H + K+ A+ +
Sbjct: 250 LIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVG 309
Query: 277 NITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALINCG 456
NI G +Q Q V++ +L LS + + KEA W +SN++ +G + QV A+I+ G
Sbjct: 310 NIVTGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWFLSNIT-AGNQQQVQAVIDAG 368
Query: 457 VIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGDNAEQVANMIEE 588
+IP + L+ D +SN L ++G +QV ++++
Sbjct: 369 LIPMIIHQLAKGDFGTQKEAAWAISN-LTISG-RKDQVEYLVQQ 410
Score = 64.1 bits (149), Expect = 4e-10
Identities = 45/179 (25%), Positives = 84/179 (46%), Gaps = 1/179 (0%)
Frame = +1
Query: 121 VQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWFLSNITAGNKQ 300
+Q A A+ NI +GT QTQ V+ +A+ F LL P + +C++AVW L NI Q
Sbjct: 131 LQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQNVCEQAVWALGNIIGDGPQ 190
Query: 301 QVQAVIDAGLLPMIVANLSKG-EFQTQKEAAWAVSNLSISGTRDQVAALINCGVIPPFCN 477
VI G++ +++ +S + W + NL + + ++P C
Sbjct: 191 CRDYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQ-EILPALCV 249
Query: 478 LLSCKDTQVINVVLDGLSNMLKMAGDNAEQVANMIEECGGIDKIEDLQTHXKMEIYKMA 654
L+ D IN+++D + + + EQ+ M+ + G + + L +H ++++ A
Sbjct: 250 LIYHTD---INILVDTVWALSYLTDGGNEQI-QMVIDSGVVPFLVPLLSHQEVKVQTAA 304
Score = 52.0 bits (119), Expect = 2e-06
Identities = 24/36 (66%), Positives = 28/36 (77%)
Frame = +3
Query: 3 DTVWAISYLTXGGNEQIQMVIXSGIVTTLXSVVVAQ 110
DTVWA+SYLT GGNEQIQMVI SG+V L ++ Q
Sbjct: 261 DTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQ 296
Score = 30.3 bits (65), Expect = 6.5
Identities = 10/26 (38%), Positives = 18/26 (69%)
Frame = +3
Query: 3 DTVWAISYLTXGGNEQIQMVIXSGIV 80
+ VW +S +T G +Q+Q VI +G++
Sbjct: 345 EAVWFLSNITAGNQQQVQAVIDAGLI 370
>BC017355-1|AAH17355.1| 521|Homo sapiens karyopherin alpha 3
(importin alpha 4) protein.
Length = 521
Score = 306 bits (751), Expect = 5e-83
Identities = 144/192 (75%), Positives = 167/192 (86%)
Frame = +1
Query: 91 IPLLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWF 270
+PLLSH+EVKVQTAALRAVGNIVTGTDEQTQVVLNCD LSHFP LL+HPKEKI KEAVWF
Sbjct: 290 VPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWF 349
Query: 271 LSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALIN 450
LSNITAGN+QQVQAVIDAGL+PMI+ L+KG+F TQKEAAWA+SNL+ISG +DQV L+
Sbjct: 350 LSNITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAISNLTISGRKDQVEYLVQ 409
Query: 451 CGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGDNAEQVANMIEECGGIDKIEDLQTHX 630
VIPPFCNLLS KD+QV+ VVLDGL N+L MAGD A +A +IEECGG++KIE LQ H
Sbjct: 410 QNVIPPFCNLLSVKDSQVVQVVLDGLKNILIMAGDEASTIAEIIEECGGLEKIEVLQQHE 469
Query: 631 KMEIYKMAYDII 666
+IYK+A++II
Sbjct: 470 NEDIYKLAFEII 481
Score = 69.7 bits (163), Expect = 9e-12
Identities = 44/164 (26%), Positives = 85/164 (51%)
Frame = +1
Query: 97 LLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWFLS 276
L+ H ++ + + A+ + G +EQ Q+V++ + LL+H + K+ A+ +
Sbjct: 250 LIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVG 309
Query: 277 NITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALINCG 456
NI G +Q Q V++ +L LS + + KEA W +SN++ +G + QV A+I+ G
Sbjct: 310 NIVTGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWFLSNIT-AGNQQQVQAVIDAG 368
Query: 457 VIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGDNAEQVANMIEE 588
+IP + L+ D +SN L ++G +QV ++++
Sbjct: 369 LIPMIIHQLAKGDFGTQKEAAWAISN-LTISG-RKDQVEYLVQQ 410
Score = 64.1 bits (149), Expect = 4e-10
Identities = 45/179 (25%), Positives = 84/179 (46%), Gaps = 1/179 (0%)
Frame = +1
Query: 121 VQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWFLSNITAGNKQ 300
+Q A A+ NI +GT QTQ V+ +A+ F LL P + +C++AVW L NI Q
Sbjct: 131 LQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQNVCEQAVWALGNIIGDGPQ 190
Query: 301 QVQAVIDAGLLPMIVANLSKG-EFQTQKEAAWAVSNLSISGTRDQVAALINCGVIPPFCN 477
VI G++ +++ +S + W + NL + + ++P C
Sbjct: 191 CRDYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQ-EILPALCV 249
Query: 478 LLSCKDTQVINVVLDGLSNMLKMAGDNAEQVANMIEECGGIDKIEDLQTHXKMEIYKMA 654
L+ D IN+++D + + + EQ+ M+ + G + + L +H ++++ A
Sbjct: 250 LIYHTD---INILVDTVWALSYLTDGGNEQI-QMVIDSGVVPFLVPLLSHQEVKVQTAA 304
Score = 52.0 bits (119), Expect = 2e-06
Identities = 24/36 (66%), Positives = 28/36 (77%)
Frame = +3
Query: 3 DTVWAISYLTXGGNEQIQMVIXSGIVTTLXSVVVAQ 110
DTVWA+SYLT GGNEQIQMVI SG+V L ++ Q
Sbjct: 261 DTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQ 296
Score = 30.3 bits (65), Expect = 6.5
Identities = 10/26 (38%), Positives = 18/26 (69%)
Frame = +3
Query: 3 DTVWAISYLTXGGNEQIQMVIXSGIV 80
+ VW +S +T G +Q+Q VI +G++
Sbjct: 345 EAVWFLSNITAGNQQQVQAVIDAGLI 370
>AL136301-1|CAH71145.1| 521|Homo sapiens karyopherin alpha 3
(importin alpha 4) protein.
Length = 521
Score = 306 bits (751), Expect = 5e-83
Identities = 144/192 (75%), Positives = 167/192 (86%)
Frame = +1
Query: 91 IPLLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWF 270
+PLLSH+EVKVQTAALRAVGNIVTGTDEQTQVVLNCD LSHFP LL+HPKEKI KEAVWF
Sbjct: 290 VPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWF 349
Query: 271 LSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALIN 450
LSNITAGN+QQVQAVIDAGL+PMI+ L+KG+F TQKEAAWA+SNL+ISG +DQV L+
Sbjct: 350 LSNITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAISNLTISGRKDQVEYLVQ 409
Query: 451 CGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGDNAEQVANMIEECGGIDKIEDLQTHX 630
VIPPFCNLLS KD+QV+ VVLDGL N+L MAGD A +A +IEECGG++KIE LQ H
Sbjct: 410 QNVIPPFCNLLSVKDSQVVQVVLDGLKNILIMAGDEASTIAEIIEECGGLEKIEVLQQHE 469
Query: 631 KMEIYKMAYDII 666
+IYK+A++II
Sbjct: 470 NEDIYKLAFEII 481
Score = 69.7 bits (163), Expect = 9e-12
Identities = 44/164 (26%), Positives = 85/164 (51%)
Frame = +1
Query: 97 LLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWFLS 276
L+ H ++ + + A+ + G +EQ Q+V++ + LL+H + K+ A+ +
Sbjct: 250 LIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVG 309
Query: 277 NITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALINCG 456
NI G +Q Q V++ +L LS + + KEA W +SN++ +G + QV A+I+ G
Sbjct: 310 NIVTGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWFLSNIT-AGNQQQVQAVIDAG 368
Query: 457 VIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGDNAEQVANMIEE 588
+IP + L+ D +SN L ++G +QV ++++
Sbjct: 369 LIPMIIHQLAKGDFGTQKEAAWAISN-LTISG-RKDQVEYLVQQ 410
Score = 64.1 bits (149), Expect = 4e-10
Identities = 45/179 (25%), Positives = 84/179 (46%), Gaps = 1/179 (0%)
Frame = +1
Query: 121 VQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWFLSNITAGNKQ 300
+Q A A+ NI +GT QTQ V+ +A+ F LL P + +C++AVW L NI Q
Sbjct: 131 LQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQNVCEQAVWALGNIIGDGPQ 190
Query: 301 QVQAVIDAGLLPMIVANLSKG-EFQTQKEAAWAVSNLSISGTRDQVAALINCGVIPPFCN 477
VI G++ +++ +S + W + NL + + ++P C
Sbjct: 191 CRDYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQ-EILPALCV 249
Query: 478 LLSCKDTQVINVVLDGLSNMLKMAGDNAEQVANMIEECGGIDKIEDLQTHXKMEIYKMA 654
L+ D IN+++D + + + EQ+ M+ + G + + L +H ++++ A
Sbjct: 250 LIYHTD---INILVDTVWALSYLTDGGNEQI-QMVIDSGVVPFLVPLLSHQEVKVQTAA 304
Score = 52.0 bits (119), Expect = 2e-06
Identities = 24/36 (66%), Positives = 28/36 (77%)
Frame = +3
Query: 3 DTVWAISYLTXGGNEQIQMVIXSGIVTTLXSVVVAQ 110
DTVWA+SYLT GGNEQIQMVI SG+V L ++ Q
Sbjct: 261 DTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQ 296
Score = 30.3 bits (65), Expect = 6.5
Identities = 10/26 (38%), Positives = 18/26 (69%)
Frame = +3
Query: 3 DTVWAISYLTXGGNEQIQMVIXSGIV 80
+ VW +S +T G +Q+Q VI +G++
Sbjct: 345 EAVWFLSNITAGNQQQVQAVIDAGLI 370
>AL135901-3|CAI40716.1| 521|Homo sapiens karyopherin alpha 3
(importin alpha 4) protein.
Length = 521
Score = 306 bits (751), Expect = 5e-83
Identities = 144/192 (75%), Positives = 167/192 (86%)
Frame = +1
Query: 91 IPLLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWF 270
+PLLSH+EVKVQTAALRAVGNIVTGTDEQTQVVLNCD LSHFP LL+HPKEKI KEAVWF
Sbjct: 290 VPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWF 349
Query: 271 LSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALIN 450
LSNITAGN+QQVQAVIDAGL+PMI+ L+KG+F TQKEAAWA+SNL+ISG +DQV L+
Sbjct: 350 LSNITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAISNLTISGRKDQVEYLVQ 409
Query: 451 CGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGDNAEQVANMIEECGGIDKIEDLQTHX 630
VIPPFCNLLS KD+QV+ VVLDGL N+L MAGD A +A +IEECGG++KIE LQ H
Sbjct: 410 QNVIPPFCNLLSVKDSQVVQVVLDGLKNILIMAGDEASTIAEIIEECGGLEKIEVLQQHE 469
Query: 631 KMEIYKMAYDII 666
+IYK+A++II
Sbjct: 470 NEDIYKLAFEII 481
Score = 69.7 bits (163), Expect = 9e-12
Identities = 44/164 (26%), Positives = 85/164 (51%)
Frame = +1
Query: 97 LLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWFLS 276
L+ H ++ + + A+ + G +EQ Q+V++ + LL+H + K+ A+ +
Sbjct: 250 LIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVG 309
Query: 277 NITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALINCG 456
NI G +Q Q V++ +L LS + + KEA W +SN++ +G + QV A+I+ G
Sbjct: 310 NIVTGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWFLSNIT-AGNQQQVQAVIDAG 368
Query: 457 VIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGDNAEQVANMIEE 588
+IP + L+ D +SN L ++G +QV ++++
Sbjct: 369 LIPMIIHQLAKGDFGTQKEAAWAISN-LTISG-RKDQVEYLVQQ 410
Score = 64.1 bits (149), Expect = 4e-10
Identities = 45/179 (25%), Positives = 84/179 (46%), Gaps = 1/179 (0%)
Frame = +1
Query: 121 VQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWFLSNITAGNKQ 300
+Q A A+ NI +GT QTQ V+ +A+ F LL P + +C++AVW L NI Q
Sbjct: 131 LQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQNVCEQAVWALGNIIGDGPQ 190
Query: 301 QVQAVIDAGLLPMIVANLSKG-EFQTQKEAAWAVSNLSISGTRDQVAALINCGVIPPFCN 477
VI G++ +++ +S + W + NL + + ++P C
Sbjct: 191 CRDYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQ-EILPALCV 249
Query: 478 LLSCKDTQVINVVLDGLSNMLKMAGDNAEQVANMIEECGGIDKIEDLQTHXKMEIYKMA 654
L+ D IN+++D + + + EQ+ M+ + G + + L +H ++++ A
Sbjct: 250 LIYHTD---INILVDTVWALSYLTDGGNEQI-QMVIDSGVVPFLVPLLSHQEVKVQTAA 304
Score = 52.0 bits (119), Expect = 2e-06
Identities = 24/36 (66%), Positives = 28/36 (77%)
Frame = +3
Query: 3 DTVWAISYLTXGGNEQIQMVIXSGIVTTLXSVVVAQ 110
DTVWA+SYLT GGNEQIQMVI SG+V L ++ Q
Sbjct: 261 DTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQ 296
Score = 30.3 bits (65), Expect = 6.5
Identities = 10/26 (38%), Positives = 18/26 (69%)
Frame = +3
Query: 3 DTVWAISYLTXGGNEQIQMVIXSGIV 80
+ VW +S +T G +Q+Q VI +G++
Sbjct: 345 EAVWFLSNITAGNQQQVQAVIDAGLI 370
>AF034756-1|AAB87693.1| 521|Homo sapiens importin-alpha homolog
protein.
Length = 521
Score = 306 bits (751), Expect = 5e-83
Identities = 144/192 (75%), Positives = 167/192 (86%)
Frame = +1
Query: 91 IPLLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWF 270
+PLLSH+EVKVQTAALRAVGNIVTGTDEQTQVVLNCD LSHFP LL+HPKEKI KEAVWF
Sbjct: 290 VPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWF 349
Query: 271 LSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALIN 450
LSNITAGN+QQVQAVIDAGL+PMI+ L+KG+F TQKEAAWA+SNL+ISG +DQV L+
Sbjct: 350 LSNITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAISNLTISGRKDQVEYLVQ 409
Query: 451 CGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGDNAEQVANMIEECGGIDKIEDLQTHX 630
VIPPFCNLLS KD+QV+ VVLDGL N+L MAGD A +A +IEECGG++KIE LQ H
Sbjct: 410 QNVIPPFCNLLSVKDSQVVQVVLDGLKNILIMAGDEASTIAEIIEECGGLEKIEVLQQHE 469
Query: 631 KMEIYKMAYDII 666
+IYK+A++II
Sbjct: 470 NEDIYKLAFEII 481
Score = 69.7 bits (163), Expect = 9e-12
Identities = 44/164 (26%), Positives = 85/164 (51%)
Frame = +1
Query: 97 LLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWFLS 276
L+ H ++ + + A+ + G +EQ Q+V++ + LL+H + K+ A+ +
Sbjct: 250 LIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVG 309
Query: 277 NITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALINCG 456
NI G +Q Q V++ +L LS + + KEA W +SN++ +G + QV A+I+ G
Sbjct: 310 NIVTGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWFLSNIT-AGNQQQVQAVIDAG 368
Query: 457 VIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGDNAEQVANMIEE 588
+IP + L+ D +SN L ++G +QV ++++
Sbjct: 369 LIPMIIHQLAKGDFGTQKEAAWAISN-LTISG-RKDQVEYLVQQ 410
Score = 62.9 bits (146), Expect = 1e-09
Identities = 45/179 (25%), Positives = 83/179 (46%), Gaps = 1/179 (0%)
Frame = +1
Query: 121 VQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWFLSNITAGNKQ 300
+Q A A+ NI +GT QTQ V +A+ F LL P + +C++AVW L NI Q
Sbjct: 131 LQFEAAWALTNIASGTSAQTQAVGQSNAVPLFLRLLRSPHQNVCEQAVWALGNIIGDGPQ 190
Query: 301 QVQAVIDAGLLPMIVANLSKG-EFQTQKEAAWAVSNLSISGTRDQVAALINCGVIPPFCN 477
VI G++ +++ +S + W + NL + + ++P C
Sbjct: 191 CRDYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPTMETVQ-EILPALCV 249
Query: 478 LLSCKDTQVINVVLDGLSNMLKMAGDNAEQVANMIEECGGIDKIEDLQTHXKMEIYKMA 654
L+ D IN+++D + + + EQ+ M+ + G + + L +H ++++ A
Sbjct: 250 LIYHTD---INILVDTVWALSYLTDGGNEQI-QMVIDSGVVPFLVPLLSHQEVKVQTAA 304
Score = 52.0 bits (119), Expect = 2e-06
Identities = 24/36 (66%), Positives = 28/36 (77%)
Frame = +3
Query: 3 DTVWAISYLTXGGNEQIQMVIXSGIVTTLXSVVVAQ 110
DTVWA+SYLT GGNEQIQMVI SG+V L ++ Q
Sbjct: 261 DTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQ 296
Score = 30.3 bits (65), Expect = 6.5
Identities = 10/26 (38%), Positives = 18/26 (69%)
Frame = +3
Query: 3 DTVWAISYLTXGGNEQIQMVIXSGIV 80
+ VW +S +T G +Q+Q VI +G++
Sbjct: 345 EAVWFLSNITAGNQQQVQAVIDAGLI 370
>AF005263-1|AAQ13404.1| 521|Homo sapiens importin alpha-3 subunit
protein.
Length = 521
Score = 306 bits (751), Expect = 5e-83
Identities = 144/192 (75%), Positives = 167/192 (86%)
Frame = +1
Query: 91 IPLLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWF 270
+PLLSH+EVKVQTAALRAVGNIVTGTDEQTQVVLNCD LSHFP LL+HPKEKI KEAVWF
Sbjct: 290 VPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWF 349
Query: 271 LSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALIN 450
LSNITAGN+QQVQAVIDAGL+PMI+ L+KG+F TQKEAAWA+SNL+ISG +DQV L+
Sbjct: 350 LSNITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAISNLTISGRKDQVEYLVQ 409
Query: 451 CGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGDNAEQVANMIEECGGIDKIEDLQTHX 630
VIPPFCNLLS KD+QV+ VVLDGL N+L MAGD A +A +IEECGG++KIE LQ H
Sbjct: 410 QNVIPPFCNLLSVKDSQVVQVVLDGLKNILIMAGDEASTIAEIIEECGGLEKIEVLQQHE 469
Query: 631 KMEIYKMAYDII 666
+IYK+A++II
Sbjct: 470 NEDIYKLAFEII 481
Score = 69.7 bits (163), Expect = 9e-12
Identities = 44/164 (26%), Positives = 85/164 (51%)
Frame = +1
Query: 97 LLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWFLS 276
L+ H ++ + + A+ + G +EQ Q+V++ + LL+H + K+ A+ +
Sbjct: 250 LIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVG 309
Query: 277 NITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALINCG 456
NI G +Q Q V++ +L LS + + KEA W +SN++ +G + QV A+I+ G
Sbjct: 310 NIVTGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWFLSNIT-AGNQQQVQAVIDAG 368
Query: 457 VIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGDNAEQVANMIEE 588
+IP + L+ D +SN L ++G +QV ++++
Sbjct: 369 LIPMIIHQLAKGDFGTQKEAAWAISN-LTISG-RKDQVEYLVQQ 410
Score = 64.1 bits (149), Expect = 4e-10
Identities = 45/179 (25%), Positives = 84/179 (46%), Gaps = 1/179 (0%)
Frame = +1
Query: 121 VQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWFLSNITAGNKQ 300
+Q A A+ NI +GT QTQ V+ +A+ F LL P + +C++AVW L NI Q
Sbjct: 131 LQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQNVCEQAVWALGNIIGDGPQ 190
Query: 301 QVQAVIDAGLLPMIVANLSKG-EFQTQKEAAWAVSNLSISGTRDQVAALINCGVIPPFCN 477
VI G++ +++ +S + W + NL + + ++P C
Sbjct: 191 CRDYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQ-EILPALCV 249
Query: 478 LLSCKDTQVINVVLDGLSNMLKMAGDNAEQVANMIEECGGIDKIEDLQTHXKMEIYKMA 654
L+ D IN+++D + + + EQ+ M+ + G + + L +H ++++ A
Sbjct: 250 LIYHTD---INILVDTVWALSYLTDGGNEQI-QMVIDSGVVPFLVPLLSHQEVKVQTAA 304
Score = 52.0 bits (119), Expect = 2e-06
Identities = 24/36 (66%), Positives = 28/36 (77%)
Frame = +3
Query: 3 DTVWAISYLTXGGNEQIQMVIXSGIVTTLXSVVVAQ 110
DTVWA+SYLT GGNEQIQMVI SG+V L ++ Q
Sbjct: 261 DTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQ 296
Score = 30.3 bits (65), Expect = 6.5
Identities = 10/26 (38%), Positives = 18/26 (69%)
Frame = +3
Query: 3 DTVWAISYLTXGGNEQIQMVIXSGIV 80
+ VW +S +T G +Q+Q VI +G++
Sbjct: 345 EAVWFLSNITAGNQQQVQAVIDAGLI 370
>BC035090-1|AAH35090.1| 521|Homo sapiens karyopherin alpha 3
(importin alpha 4) protein.
Length = 521
Score = 302 bits (742), Expect = 6e-82
Identities = 143/192 (74%), Positives = 166/192 (86%)
Frame = +1
Query: 91 IPLLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWF 270
+PLLSH+EVKVQTAALRAVGNIVTGTDEQTQVVLNCD LSHF LL+HPKEKI KEAVWF
Sbjct: 290 VPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFQNLLSHPKEKINKEAVWF 349
Query: 271 LSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALIN 450
LSNITAGN+QQVQAVIDAGL+PMI+ L+KG+F TQKEAAWA+SNL+ISG +DQV L+
Sbjct: 350 LSNITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAISNLTISGRKDQVEYLVQ 409
Query: 451 CGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGDNAEQVANMIEECGGIDKIEDLQTHX 630
VIPPFCNLLS KD+QV+ VVLDGL N+L MAGD A +A +IEECGG++KIE LQ H
Sbjct: 410 QDVIPPFCNLLSVKDSQVVQVVLDGLKNILIMAGDEASTIAEIIEECGGLEKIEVLQQHE 469
Query: 631 KMEIYKMAYDII 666
+IYK+A++II
Sbjct: 470 NEDIYKLAFEII 481
Score = 69.7 bits (163), Expect = 9e-12
Identities = 44/164 (26%), Positives = 85/164 (51%)
Frame = +1
Query: 97 LLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWFLS 276
L+ H ++ + + A+ + G +EQ Q+V++ + LL+H + K+ A+ +
Sbjct: 250 LIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVG 309
Query: 277 NITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALINCG 456
NI G +Q Q V++ +L LS + + KEA W +SN++ +G + QV A+I+ G
Sbjct: 310 NIVTGTDEQTQVVLNCDVLSHFQNLLSHPKEKINKEAVWFLSNIT-AGNQQQVQAVIDAG 368
Query: 457 VIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGDNAEQVANMIEE 588
+IP + L+ D +SN L ++G +QV ++++
Sbjct: 369 LIPMIIHQLAKGDFGTQKEAAWAISN-LTISG-RKDQVEYLVQQ 410
Score = 62.5 bits (145), Expect = 1e-09
Identities = 44/179 (24%), Positives = 84/179 (46%), Gaps = 1/179 (0%)
Frame = +1
Query: 121 VQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWFLSNITAGNKQ 300
+Q A A+ NI +GT QTQ ++ +A+ F LL P + +C++AVW L NI Q
Sbjct: 131 LQFEAAWALTNIASGTSAQTQDIVQSNAVPLFLRLLRSPHQNVCEQAVWALGNIIGDGPQ 190
Query: 301 QVQAVIDAGLLPMIVANLSKG-EFQTQKEAAWAVSNLSISGTRDQVAALINCGVIPPFCN 477
VI G++ +++ +S + W + NL + + ++P C
Sbjct: 191 CRDYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQ-EILPALCV 249
Query: 478 LLSCKDTQVINVVLDGLSNMLKMAGDNAEQVANMIEECGGIDKIEDLQTHXKMEIYKMA 654
L+ D IN+++D + + + EQ+ M+ + G + + L +H ++++ A
Sbjct: 250 LIYHTD---INILVDTVWALSYLTDGGNEQI-QMVIDSGVVPFLVPLLSHQEVKVQTAA 304
Score = 52.0 bits (119), Expect = 2e-06
Identities = 24/36 (66%), Positives = 28/36 (77%)
Frame = +3
Query: 3 DTVWAISYLTXGGNEQIQMVIXSGIVTTLXSVVVAQ 110
DTVWA+SYLT GGNEQIQMVI SG+V L ++ Q
Sbjct: 261 DTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQ 296
Score = 30.3 bits (65), Expect = 6.5
Identities = 10/26 (38%), Positives = 18/26 (69%)
Frame = +3
Query: 3 DTVWAISYLTXGGNEQIQMVIXSGIV 80
+ VW +S +T G +Q+Q VI +G++
Sbjct: 345 EAVWFLSNITAGNQQQVQAVIDAGLI 370
>AK223480-1|BAD97200.1| 521|Homo sapiens karyopherin alpha 3
variant protein.
Length = 521
Score = 300 bits (737), Expect = 2e-81
Identities = 143/192 (74%), Positives = 166/192 (86%)
Frame = +1
Query: 91 IPLLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWF 270
+PLLSH+EVKVQTAALRAVGNIVTGTDEQTQVVLNCD LSHFP LL+HPKEKI KEAVWF
Sbjct: 290 VPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWF 349
Query: 271 LSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALIN 450
LSNITAGN+QQVQAVIDAGL+PMI+ L+KG+F TQKEAA A+SNL+ISG +DQV L+
Sbjct: 350 LSNITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQKEAARAISNLTISGRKDQVEYLVQ 409
Query: 451 CGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGDNAEQVANMIEECGGIDKIEDLQTHX 630
VIPPFCNLLS KD+QV+ VVLDGL N+L MAGD A +A +IEECGG++KIE LQ H
Sbjct: 410 QNVIPPFCNLLSVKDSQVVQVVLDGLKNILIMAGDEASTIAEIIEECGGLEKIEVLQQHE 469
Query: 631 KMEIYKMAYDII 666
+IYK+A++II
Sbjct: 470 NEDIYKLAFEII 481
Score = 70.5 bits (165), Expect = 5e-12
Identities = 44/164 (26%), Positives = 85/164 (51%)
Frame = +1
Query: 97 LLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWFLS 276
L+ H ++ + + A+ + G +EQ Q+V++ + LL+H + K+ A+ +
Sbjct: 250 LIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVG 309
Query: 277 NITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALINCG 456
NI G +Q Q V++ +L LS + + KEA W +SN++ +G + QV A+I+ G
Sbjct: 310 NIVTGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWFLSNIT-AGNQQQVQAVIDAG 368
Query: 457 VIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGDNAEQVANMIEE 588
+IP + L+ D +SN L ++G +QV ++++
Sbjct: 369 LIPMIIHQLAKGDFGTQKEAARAISN-LTISG-RKDQVEYLVQQ 410
Score = 64.1 bits (149), Expect = 4e-10
Identities = 45/179 (25%), Positives = 84/179 (46%), Gaps = 1/179 (0%)
Frame = +1
Query: 121 VQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWFLSNITAGNKQ 300
+Q A A+ NI +GT QTQ V+ +A+ F LL P + +C++AVW L NI Q
Sbjct: 131 LQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQNVCEQAVWALGNIIGDGPQ 190
Query: 301 QVQAVIDAGLLPMIVANLSKG-EFQTQKEAAWAVSNLSISGTRDQVAALINCGVIPPFCN 477
VI G++ +++ +S + W + NL + + ++P C
Sbjct: 191 CRDYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQ-EILPALCV 249
Query: 478 LLSCKDTQVINVVLDGLSNMLKMAGDNAEQVANMIEECGGIDKIEDLQTHXKMEIYKMA 654
L+ D IN+++D + + + EQ+ M+ + G + + L +H ++++ A
Sbjct: 250 LIYHTD---INILVDTVWALSYLTDGGNEQI-QMVIDSGVVPFLVPLLSHQEVKVQTAA 304
Score = 52.0 bits (119), Expect = 2e-06
Identities = 24/36 (66%), Positives = 28/36 (77%)
Frame = +3
Query: 3 DTVWAISYLTXGGNEQIQMVIXSGIVTTLXSVVVAQ 110
DTVWA+SYLT GGNEQIQMVI SG+V L ++ Q
Sbjct: 261 DTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQ 296
Score = 30.3 bits (65), Expect = 6.5
Identities = 10/26 (38%), Positives = 18/26 (69%)
Frame = +3
Query: 3 DTVWAISYLTXGGNEQIQMVIXSGIV 80
+ VW +S +T G +Q+Q VI +G++
Sbjct: 345 EAVWFLSNITAGNQQQVQAVIDAGLI 370
>BT006665-1|AAP35311.1| 529|Homo sapiens karyopherin alpha 2 (RAG
cohort 1, importin alpha 1) protein.
Length = 529
Score = 216 bits (527), Expect = 7e-56
Identities = 101/194 (52%), Positives = 142/194 (73%), Gaps = 2/194 (1%)
Frame = +1
Query: 91 IPLLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWF 270
+ LL E+ + T ALRA+GNIVTGTDEQTQVV++ AL+ FP+LLT+PK I KEA W
Sbjct: 299 VKLLGASELPIVTPALRAIGNIVTGTDEQTQVVIDAGALAVFPSLLTNPKTNIQKEATWT 358
Query: 271 LSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALIN 450
+SNITAG + Q+Q V++ GL+P +V+ LSK +F+TQKEA WAV+N + GT +Q+ L++
Sbjct: 359 MSNITAGRQDQIQQVVNHGLVPFLVSVLSKADFKTQKEAVWAVTNYTSGGTVEQIVYLVH 418
Query: 451 CGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGD--NAEQVANMIEECGGIDKIEDLQT 624
CG+I P NLL+ KDT++I V+LD +SN+ + A + E+++ MIEECGG+DKIE LQ
Sbjct: 419 CGIIEPLMNLLTAKDTKIILVILDAISNIFQAAENLGETEKLSIMIEECGGLDKIEALQN 478
Query: 625 HXKMEIYKMAYDII 666
H +YK + +I
Sbjct: 479 HENESVYKASLSLI 492
Score = 80.2 bits (189), Expect = 6e-15
Identities = 52/192 (27%), Positives = 95/192 (49%)
Frame = +1
Query: 91 IPLLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWF 270
+ LL H + +V A+ + G +E+ +V+ + LL + I A+
Sbjct: 257 VRLLHHDDPEVLADTCWAISYLTDGPNERIGMVVKTGVVPQLVKLLGASELPIVTPALRA 316
Query: 271 LSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALIN 450
+ NI G +Q Q VIDAG L + + L+ + QKEA W +SN++ +G +DQ+ ++N
Sbjct: 317 IGNIVTGTDEQTQVVIDAGALAVFPSLLTNPKTNIQKEATWTMSNIT-AGRQDQIQQVVN 375
Query: 451 CGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGDNAEQVANMIEECGGIDKIEDLQTHX 630
G++P ++LS D + + ++N +G EQ+ ++ CG I+ + +L T
Sbjct: 376 HGLVPFLVSVLSKADFKTQKEAVWAVTNY--TSGGTVEQIVYLV-HCGIIEPLMNLLTAK 432
Query: 631 KMEIYKMAYDII 666
+I + D I
Sbjct: 433 DTKIILVILDAI 444
Score = 53.2 bits (122), Expect = 8e-07
Identities = 47/195 (24%), Positives = 82/195 (42%), Gaps = 7/195 (3%)
Frame = +1
Query: 91 IPLLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHP--KEKIC---K 255
I LL+ + A+ A+GNI +V+ A+ ALL P C +
Sbjct: 168 ISLLASPHAHISEQAVWALGNIAGDGSVFRDLVIKYGAVDPLLALLAVPDMSSLACGYLR 227
Query: 256 EAVWFLSNITAGNKQQVQAVIDA--GLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRD 429
W LSN+ NK IDA +LP +V L + + + WA+S L+ G +
Sbjct: 228 NLTWTLSNL-CRNKNPAPP-IDAVEQILPTLVRLLHHDDPEVLADTCWAISYLT-DGPNE 284
Query: 430 QVAALINCGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGDNAEQVANMIEECGGIDKI 609
++ ++ GV+P LL + ++ L + N++ ++ ++ + G +
Sbjct: 285 RIGMVVKTGVVPQLVKLLGASELPIVTPALRAIGNIV----TGTDEQTQVVIDAGALAVF 340
Query: 610 EDLQTHXKMEIYKMA 654
L T+ K I K A
Sbjct: 341 PSLLTNPKTNIQKEA 355
Score = 52.0 bits (119), Expect = 2e-06
Identities = 26/82 (31%), Positives = 44/82 (53%), Gaps = 2/82 (2%)
Frame = +1
Query: 256 EAVWFLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGT--RD 429
E+ W L+NI +G +Q + V+D G +P ++ L+ ++A WA+ N++ G+ RD
Sbjct: 139 ESAWALTNIASGTSEQTKVVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSVFRD 198
Query: 430 QVAALINCGVIPPFCNLLSCKD 495
V I G + P LL+ D
Sbjct: 199 LV---IKYGAVDPLLALLAVPD 217
Score = 50.8 bits (116), Expect = 4e-06
Identities = 32/101 (31%), Positives = 51/101 (50%), Gaps = 5/101 (4%)
Frame = +1
Query: 121 VQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWFLSNITAGNKQ 300
+Q + A+ NI +GT EQT+VV++ A+ F +LL P I ++AVW L NI
Sbjct: 136 IQFESAWALTNIASGTSEQTKVVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSV 195
Query: 301 QVQAVIDAGLLPMIVANLSKGEFQT-----QKEAAWAVSNL 408
VI G + ++A L+ + + + W +SNL
Sbjct: 196 FRDLVIKYGAVDPLLALLAVPDMSSLACGYLRNLTWTLSNL 236
Score = 48.8 bits (111), Expect = 2e-05
Identities = 30/103 (29%), Positives = 57/103 (55%), Gaps = 1/103 (0%)
Frame = +1
Query: 304 VQAVIDAGLLPMIVANLSKGEFQT-QKEAAWAVSNLSISGTRDQVAALINCGVIPPFCNL 480
+ +I AGL+P V+ L + + Q E+AWA++N++ SGT +Q +++ G IP F +L
Sbjct: 112 IDNIIRAGLIPKFVSFLGRTDCSPIQFESAWALTNIA-SGTSEQTKVVVDGGAIPAFISL 170
Query: 481 LSCKDTQVINVVLDGLSNMLKMAGDNAEQVANMIEECGGIDKI 609
L+ + + L N +AGD + +++ + G +D +
Sbjct: 171 LASPHAHISEQAVWALGN---IAGDGS-VFRDLVIKYGAVDPL 209
Score = 42.3 bits (95), Expect = 0.001
Identities = 19/35 (54%), Positives = 25/35 (71%)
Frame = +3
Query: 3 DTVWAISYLTXGGNEQIQMVIXSGIVTTLXSVVVA 107
DT WAISYLT G NE+I MV+ +G+V L ++ A
Sbjct: 270 DTCWAISYLTDGPNERIGMVVKTGVVPQLVKLLGA 304
Score = 31.9 bits (69), Expect = 2.1
Identities = 13/33 (39%), Positives = 20/33 (60%)
Frame = +3
Query: 3 DTVWAISYLTXGGNEQIQMVIXSGIVTTLXSVV 101
+ W +S +T G +QIQ V+ G+V L SV+
Sbjct: 354 EATWTMSNITAGRQDQIQQVVNHGLVPFLVSVL 386
Score = 29.9 bits (64), Expect = 8.5
Identities = 13/40 (32%), Positives = 25/40 (62%), Gaps = 1/40 (2%)
Frame = +3
Query: 3 DTVWAISYLTXGGN-EQIQMVIXSGIVTTLXSVVVAQGSE 119
+ VWA++ T GG EQI ++ GI+ L +++ A+ ++
Sbjct: 396 EAVWAVTNYTSGGTVEQIVYLVHCGIIEPLMNLLTAKDTK 435
>BC005978-1|AAH05978.1| 529|Homo sapiens karyopherin alpha 2 (RAG
cohort 1, importin alpha 1) protein.
Length = 529
Score = 216 bits (527), Expect = 7e-56
Identities = 101/194 (52%), Positives = 142/194 (73%), Gaps = 2/194 (1%)
Frame = +1
Query: 91 IPLLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWF 270
+ LL E+ + T ALRA+GNIVTGTDEQTQVV++ AL+ FP+LLT+PK I KEA W
Sbjct: 299 VKLLGASELPIVTPALRAIGNIVTGTDEQTQVVIDAGALAVFPSLLTNPKTNIQKEATWT 358
Query: 271 LSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALIN 450
+SNITAG + Q+Q V++ GL+P +V+ LSK +F+TQKEA WAV+N + GT +Q+ L++
Sbjct: 359 MSNITAGRQDQIQQVVNHGLVPFLVSVLSKADFKTQKEAVWAVTNYTSGGTVEQIVYLVH 418
Query: 451 CGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGD--NAEQVANMIEECGGIDKIEDLQT 624
CG+I P NLL+ KDT++I V+LD +SN+ + A + E+++ MIEECGG+DKIE LQ
Sbjct: 419 CGIIEPLMNLLTAKDTKIILVILDAISNIFQAAENLGETEKLSIMIEECGGLDKIEALQN 478
Query: 625 HXKMEIYKMAYDII 666
H +YK + +I
Sbjct: 479 HENESVYKASLSLI 492
Score = 80.2 bits (189), Expect = 6e-15
Identities = 52/192 (27%), Positives = 95/192 (49%)
Frame = +1
Query: 91 IPLLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWF 270
+ LL H + +V A+ + G +E+ +V+ + LL + I A+
Sbjct: 257 VRLLHHDDPEVLADTCWAISYLTDGPNERIGMVVKTGVVPQLVKLLGASELPIVTPALRA 316
Query: 271 LSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALIN 450
+ NI G +Q Q VIDAG L + + L+ + QKEA W +SN++ +G +DQ+ ++N
Sbjct: 317 IGNIVTGTDEQTQVVIDAGALAVFPSLLTNPKTNIQKEATWTMSNIT-AGRQDQIQQVVN 375
Query: 451 CGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGDNAEQVANMIEECGGIDKIEDLQTHX 630
G++P ++LS D + + ++N +G EQ+ ++ CG I+ + +L T
Sbjct: 376 HGLVPFLVSVLSKADFKTQKEAVWAVTNY--TSGGTVEQIVYLV-HCGIIEPLMNLLTAK 432
Query: 631 KMEIYKMAYDII 666
+I + D I
Sbjct: 433 DTKIILVILDAI 444
Score = 53.2 bits (122), Expect = 8e-07
Identities = 47/195 (24%), Positives = 82/195 (42%), Gaps = 7/195 (3%)
Frame = +1
Query: 91 IPLLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHP--KEKIC---K 255
I LL+ + A+ A+GNI +V+ A+ ALL P C +
Sbjct: 168 ISLLASPHAHISEQAVWALGNIAGDGSVFRDLVIKYGAVDPLLALLAVPDMSSLACGYLR 227
Query: 256 EAVWFLSNITAGNKQQVQAVIDA--GLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRD 429
W LSN+ NK IDA +LP +V L + + + WA+S L+ G +
Sbjct: 228 NLTWTLSNL-CRNKNPAPP-IDAVEQILPTLVRLLHHDDPEVLADTCWAISYLT-DGPNE 284
Query: 430 QVAALINCGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGDNAEQVANMIEECGGIDKI 609
++ ++ GV+P LL + ++ L + N++ ++ ++ + G +
Sbjct: 285 RIGMVVKTGVVPQLVKLLGASELPIVTPALRAIGNIV----TGTDEQTQVVIDAGALAVF 340
Query: 610 EDLQTHXKMEIYKMA 654
L T+ K I K A
Sbjct: 341 PSLLTNPKTNIQKEA 355
Score = 52.0 bits (119), Expect = 2e-06
Identities = 26/82 (31%), Positives = 44/82 (53%), Gaps = 2/82 (2%)
Frame = +1
Query: 256 EAVWFLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGT--RD 429
E+ W L+NI +G +Q + V+D G +P ++ L+ ++A WA+ N++ G+ RD
Sbjct: 139 ESAWALTNIASGTSEQTKVVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSVFRD 198
Query: 430 QVAALINCGVIPPFCNLLSCKD 495
V I G + P LL+ D
Sbjct: 199 LV---IKYGAVDPLLALLAVPD 217
Score = 50.8 bits (116), Expect = 4e-06
Identities = 32/101 (31%), Positives = 51/101 (50%), Gaps = 5/101 (4%)
Frame = +1
Query: 121 VQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWFLSNITAGNKQ 300
+Q + A+ NI +GT EQT+VV++ A+ F +LL P I ++AVW L NI
Sbjct: 136 IQFESAWALTNIASGTSEQTKVVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSV 195
Query: 301 QVQAVIDAGLLPMIVANLSKGEFQT-----QKEAAWAVSNL 408
VI G + ++A L+ + + + W +SNL
Sbjct: 196 FRDLVIKYGAVDPLLALLAVPDMSSLACGYLRNLTWTLSNL 236
Score = 48.8 bits (111), Expect = 2e-05
Identities = 30/103 (29%), Positives = 57/103 (55%), Gaps = 1/103 (0%)
Frame = +1
Query: 304 VQAVIDAGLLPMIVANLSKGEFQT-QKEAAWAVSNLSISGTRDQVAALINCGVIPPFCNL 480
+ +I AGL+P V+ L + + Q E+AWA++N++ SGT +Q +++ G IP F +L
Sbjct: 112 IDNIIRAGLIPKFVSFLGRTDCSPIQFESAWALTNIA-SGTSEQTKVVVDGGAIPAFISL 170
Query: 481 LSCKDTQVINVVLDGLSNMLKMAGDNAEQVANMIEECGGIDKI 609
L+ + + L N +AGD + +++ + G +D +
Sbjct: 171 LASPHAHISEQAVWALGN---IAGDGS-VFRDLVIKYGAVDPL 209
Score = 42.3 bits (95), Expect = 0.001
Identities = 19/35 (54%), Positives = 25/35 (71%)
Frame = +3
Query: 3 DTVWAISYLTXGGNEQIQMVIXSGIVTTLXSVVVA 107
DT WAISYLT G NE+I MV+ +G+V L ++ A
Sbjct: 270 DTCWAISYLTDGPNERIGMVVKTGVVPQLVKLLGA 304
Score = 31.9 bits (69), Expect = 2.1
Identities = 13/33 (39%), Positives = 20/33 (60%)
Frame = +3
Query: 3 DTVWAISYLTXGGNEQIQMVIXSGIVTTLXSVV 101
+ W +S +T G +QIQ V+ G+V L SV+
Sbjct: 354 EATWTMSNITAGRQDQIQQVVNHGLVPFLVSVL 386
Score = 29.9 bits (64), Expect = 8.5
Identities = 13/40 (32%), Positives = 25/40 (62%), Gaps = 1/40 (2%)
Frame = +3
Query: 3 DTVWAISYLTXGGN-EQIQMVIXSGIVTTLXSVVVAQGSE 119
+ VWA++ T GG EQI ++ GI+ L +++ A+ ++
Sbjct: 396 EAVWAVTNYTSGGTVEQIVYLVHCGIIEPLMNLLTAKDTK 435
>U28386-1|AAA69957.1| 529|Homo sapiens hSRP1alpha protein.
Length = 529
Score = 215 bits (525), Expect = 1e-55
Identities = 101/194 (52%), Positives = 141/194 (72%), Gaps = 2/194 (1%)
Frame = +1
Query: 91 IPLLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWF 270
+ LL E+ + T ALRA+GNIVTGTDEQTQVV++ AL+ FP+LLT+PK I KEA W
Sbjct: 299 VKLLGASELPIVTPALRAIGNIVTGTDEQTQVVIDAGALAVFPSLLTNPKTNIQKEATWT 358
Query: 271 LSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALIN 450
+SNITAG + Q+Q V++ GL+P +V+ LSK +F+TQKEA WAV+N + GT +Q+ L++
Sbjct: 359 MSNITAGRQDQIQQVVNHGLVPFLVSVLSKADFKTQKEAVWAVTNYTSGGTVEQIVYLVH 418
Query: 451 CGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAG--DNAEQVANMIEECGGIDKIEDLQT 624
CG+I P NLL+ KDT++I V+LD +SN+ + A E+++ MIEECGG+DKIE LQ
Sbjct: 419 CGIIEPLMNLLTAKDTKIILVILDAISNIFQAAEKLGETEKLSIMIEECGGLDKIEALQN 478
Query: 625 HXKMEIYKMAYDII 666
H +YK + +I
Sbjct: 479 HENESVYKASLSLI 492
Score = 80.2 bits (189), Expect = 6e-15
Identities = 52/192 (27%), Positives = 95/192 (49%)
Frame = +1
Query: 91 IPLLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWF 270
+ LL H + +V A+ + G +E+ +V+ + LL + I A+
Sbjct: 257 VRLLHHDDPEVLADTCWAISYLTDGPNERIGMVVKTGVVPQLVKLLGASELPIVTPALRA 316
Query: 271 LSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALIN 450
+ NI G +Q Q VIDAG L + + L+ + QKEA W +SN++ +G +DQ+ ++N
Sbjct: 317 IGNIVTGTDEQTQVVIDAGALAVFPSLLTNPKTNIQKEATWTMSNIT-AGRQDQIQQVVN 375
Query: 451 CGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGDNAEQVANMIEECGGIDKIEDLQTHX 630
G++P ++LS D + + ++N +G EQ+ ++ CG I+ + +L T
Sbjct: 376 HGLVPFLVSVLSKADFKTQKEAVWAVTNY--TSGGTVEQIVYLV-HCGIIEPLMNLLTAK 432
Query: 631 KMEIYKMAYDII 666
+I + D I
Sbjct: 433 DTKIILVILDAI 444
Score = 53.6 bits (123), Expect = 6e-07
Identities = 27/82 (32%), Positives = 45/82 (54%), Gaps = 2/82 (2%)
Frame = +1
Query: 256 EAVWFLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGT--RD 429
E+ W L+NI +G +Q +AV+D G +P ++ L+ ++A WA+ N++ G+ RD
Sbjct: 139 ESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSVFRD 198
Query: 430 QVAALINCGVIPPFCNLLSCKD 495
V I G + P LL+ D
Sbjct: 199 LV---IKYGAVDPLLALLAVPD 217
Score = 53.2 bits (122), Expect = 8e-07
Identities = 47/195 (24%), Positives = 82/195 (42%), Gaps = 7/195 (3%)
Frame = +1
Query: 91 IPLLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHP--KEKIC---K 255
I LL+ + A+ A+GNI +V+ A+ ALL P C +
Sbjct: 168 ISLLASPHAHISEQAVWALGNIAGDGSVFRDLVIKYGAVDPLLALLAVPDMSSLACGYLR 227
Query: 256 EAVWFLSNITAGNKQQVQAVIDA--GLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRD 429
W LSN+ NK IDA +LP +V L + + + WA+S L+ G +
Sbjct: 228 NLTWTLSNL-CRNKNPAPP-IDAVEQILPTLVRLLHHDDPEVLADTCWAISYLT-DGPNE 284
Query: 430 QVAALINCGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGDNAEQVANMIEECGGIDKI 609
++ ++ GV+P LL + ++ L + N++ ++ ++ + G +
Sbjct: 285 RIGMVVKTGVVPQLVKLLGASELPIVTPALRAIGNIV----TGTDEQTQVVIDAGALAVF 340
Query: 610 EDLQTHXKMEIYKMA 654
L T+ K I K A
Sbjct: 341 PSLLTNPKTNIQKEA 355
Score = 50.4 bits (115), Expect = 6e-06
Identities = 31/103 (30%), Positives = 58/103 (56%), Gaps = 1/103 (0%)
Frame = +1
Query: 304 VQAVIDAGLLPMIVANLSKGEFQT-QKEAAWAVSNLSISGTRDQVAALINCGVIPPFCNL 480
+ +I AGL+P V+ L + + Q E+AWA++N++ SGT +Q A+++ G IP F +L
Sbjct: 112 IDNIIRAGLIPKFVSFLGRTDCSPIQFESAWALTNIA-SGTSEQTKAVVDGGAIPAFISL 170
Query: 481 LSCKDTQVINVVLDGLSNMLKMAGDNAEQVANMIEECGGIDKI 609
L+ + + L N +AGD + +++ + G +D +
Sbjct: 171 LASPHAHISEQAVWALGN---IAGDGS-VFRDLVIKYGAVDPL 209
Score = 49.2 bits (112), Expect = 1e-05
Identities = 31/101 (30%), Positives = 50/101 (49%), Gaps = 5/101 (4%)
Frame = +1
Query: 121 VQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWFLSNITAGNKQ 300
+Q + A+ NI +GT EQT+ V++ A+ F +LL P I ++AVW L NI
Sbjct: 136 IQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSV 195
Query: 301 QVQAVIDAGLLPMIVANLSKGEFQT-----QKEAAWAVSNL 408
VI G + ++A L+ + + + W +SNL
Sbjct: 196 FRDLVIKYGAVDPLLALLAVPDMSSLACGYLRNLTWTLSNL 236
Score = 42.3 bits (95), Expect = 0.001
Identities = 19/35 (54%), Positives = 25/35 (71%)
Frame = +3
Query: 3 DTVWAISYLTXGGNEQIQMVIXSGIVTTLXSVVVA 107
DT WAISYLT G NE+I MV+ +G+V L ++ A
Sbjct: 270 DTCWAISYLTDGPNERIGMVVKTGVVPQLVKLLGA 304
Score = 31.9 bits (69), Expect = 2.1
Identities = 13/33 (39%), Positives = 20/33 (60%)
Frame = +3
Query: 3 DTVWAISYLTXGGNEQIQMVIXSGIVTTLXSVV 101
+ W +S +T G +QIQ V+ G+V L SV+
Sbjct: 354 EATWTMSNITAGRQDQIQQVVNHGLVPFLVSVL 386
Score = 29.9 bits (64), Expect = 8.5
Identities = 13/40 (32%), Positives = 25/40 (62%), Gaps = 1/40 (2%)
Frame = +3
Query: 3 DTVWAISYLTXGGN-EQIQMVIXSGIVTTLXSVVVAQGSE 119
+ VWA++ T GG EQI ++ GI+ L +++ A+ ++
Sbjct: 396 EAVWAVTNYTSGGTVEQIVYLVHCGIIEPLMNLLTAKDTK 435
>U09559-1|AAA65700.1| 529|Homo sapiens Rch1 protein.
Length = 529
Score = 215 bits (525), Expect = 1e-55
Identities = 101/194 (52%), Positives = 141/194 (72%), Gaps = 2/194 (1%)
Frame = +1
Query: 91 IPLLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWF 270
+ LL E+ + T ALRA+GNIVTGTDEQTQVV++ AL+ FP+LLT+PK I KEA W
Sbjct: 299 VKLLGASELPIVTPALRAIGNIVTGTDEQTQVVIDAGALAVFPSLLTNPKTNIQKEATWT 358
Query: 271 LSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALIN 450
+SNITAG + Q+Q V++ GL+P +V+ LSK +F+TQKEA WAV+N + GT +Q+ L++
Sbjct: 359 MSNITAGRQDQIQQVVNHGLVPFLVSVLSKADFKTQKEAVWAVTNYTSGGTVEQIVYLVH 418
Query: 451 CGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAG--DNAEQVANMIEECGGIDKIEDLQT 624
CG+I P NLL+ KDT++I V+LD +SN+ + A E+++ MIEECGG+DKIE LQ
Sbjct: 419 CGIIEPLMNLLTAKDTKIILVILDAISNIFQAAEKLGETEKLSIMIEECGGLDKIEALQN 478
Query: 625 HXKMEIYKMAYDII 666
H +YK + +I
Sbjct: 479 HENESVYKASLSLI 492
Score = 80.2 bits (189), Expect = 6e-15
Identities = 52/192 (27%), Positives = 95/192 (49%)
Frame = +1
Query: 91 IPLLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWF 270
+ LL H + +V A+ + G +E+ +V+ + LL + I A+
Sbjct: 257 VRLLHHDDPEVLADTCWAISYLTDGPNERIGMVVKTGVVPQLVKLLGASELPIVTPALRA 316
Query: 271 LSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALIN 450
+ NI G +Q Q VIDAG L + + L+ + QKEA W +SN++ +G +DQ+ ++N
Sbjct: 317 IGNIVTGTDEQTQVVIDAGALAVFPSLLTNPKTNIQKEATWTMSNIT-AGRQDQIQQVVN 375
Query: 451 CGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGDNAEQVANMIEECGGIDKIEDLQTHX 630
G++P ++LS D + + ++N +G EQ+ ++ CG I+ + +L T
Sbjct: 376 HGLVPFLVSVLSKADFKTQKEAVWAVTNY--TSGGTVEQIVYLV-HCGIIEPLMNLLTAK 432
Query: 631 KMEIYKMAYDII 666
+I + D I
Sbjct: 433 DTKIILVILDAI 444
Score = 53.6 bits (123), Expect = 6e-07
Identities = 27/82 (32%), Positives = 45/82 (54%), Gaps = 2/82 (2%)
Frame = +1
Query: 256 EAVWFLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGT--RD 429
E+ W L+NI +G +Q +AV+D G +P ++ L+ ++A WA+ N++ G+ RD
Sbjct: 139 ESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSVFRD 198
Query: 430 QVAALINCGVIPPFCNLLSCKD 495
V I G + P LL+ D
Sbjct: 199 LV---IKYGAVDPLLALLAVPD 217
Score = 53.2 bits (122), Expect = 8e-07
Identities = 47/195 (24%), Positives = 82/195 (42%), Gaps = 7/195 (3%)
Frame = +1
Query: 91 IPLLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHP--KEKIC---K 255
I LL+ + A+ A+GNI +V+ A+ ALL P C +
Sbjct: 168 ISLLASPHAHISEQAVWALGNIAGDGSVFRDLVIKYGAVDPLLALLAVPDMSSLACGYLR 227
Query: 256 EAVWFLSNITAGNKQQVQAVIDA--GLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRD 429
W LSN+ NK IDA +LP +V L + + + WA+S L+ G +
Sbjct: 228 NLTWTLSNL-CRNKNPAPP-IDAVEQILPTLVRLLHHDDPEVLADTCWAISYLT-DGPNE 284
Query: 430 QVAALINCGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGDNAEQVANMIEECGGIDKI 609
++ ++ GV+P LL + ++ L + N++ ++ ++ + G +
Sbjct: 285 RIGMVVKTGVVPQLVKLLGASELPIVTPALRAIGNIV----TGTDEQTQVVIDAGALAVF 340
Query: 610 EDLQTHXKMEIYKMA 654
L T+ K I K A
Sbjct: 341 PSLLTNPKTNIQKEA 355
Score = 50.4 bits (115), Expect = 6e-06
Identities = 31/103 (30%), Positives = 58/103 (56%), Gaps = 1/103 (0%)
Frame = +1
Query: 304 VQAVIDAGLLPMIVANLSKGEFQT-QKEAAWAVSNLSISGTRDQVAALINCGVIPPFCNL 480
+ +I AGL+P V+ L + + Q E+AWA++N++ SGT +Q A+++ G IP F +L
Sbjct: 112 IDNIIRAGLIPKFVSFLGRTDCSPIQFESAWALTNIA-SGTSEQTKAVVDGGAIPAFISL 170
Query: 481 LSCKDTQVINVVLDGLSNMLKMAGDNAEQVANMIEECGGIDKI 609
L+ + + L N +AGD + +++ + G +D +
Sbjct: 171 LASPHAHISEQAVWALGN---IAGDGS-VFRDLVIKYGAVDPL 209
Score = 49.2 bits (112), Expect = 1e-05
Identities = 31/101 (30%), Positives = 50/101 (49%), Gaps = 5/101 (4%)
Frame = +1
Query: 121 VQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWFLSNITAGNKQ 300
+Q + A+ NI +GT EQT+ V++ A+ F +LL P I ++AVW L NI
Sbjct: 136 IQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSV 195
Query: 301 QVQAVIDAGLLPMIVANLSKGEFQT-----QKEAAWAVSNL 408
VI G + ++A L+ + + + W +SNL
Sbjct: 196 FRDLVIKYGAVDPLLALLAVPDMSSLACGYLRNLTWTLSNL 236
Score = 42.3 bits (95), Expect = 0.001
Identities = 19/35 (54%), Positives = 25/35 (71%)
Frame = +3
Query: 3 DTVWAISYLTXGGNEQIQMVIXSGIVTTLXSVVVA 107
DT WAISYLT G NE+I MV+ +G+V L ++ A
Sbjct: 270 DTCWAISYLTDGPNERIGMVVKTGVVPQLVKLLGA 304
Score = 31.9 bits (69), Expect = 2.1
Identities = 13/33 (39%), Positives = 20/33 (60%)
Frame = +3
Query: 3 DTVWAISYLTXGGNEQIQMVIXSGIVTTLXSVV 101
+ W +S +T G +QIQ V+ G+V L SV+
Sbjct: 354 EATWTMSNITAGRQDQIQQVVNHGLVPFLVSVL 386
Score = 29.9 bits (64), Expect = 8.5
Identities = 13/40 (32%), Positives = 25/40 (62%), Gaps = 1/40 (2%)
Frame = +3
Query: 3 DTVWAISYLTXGGN-EQIQMVIXSGIVTTLXSVVVAQGSE 119
+ VWA++ T GG EQI ++ GI+ L +++ A+ ++
Sbjct: 396 EAVWAVTNYTSGGTVEQIVYLVHCGIIEPLMNLLTAKDTK 435
>BC067848-1|AAH67848.1| 529|Homo sapiens karyopherin alpha 2 (RAG
cohort 1, importin alpha 1) protein.
Length = 529
Score = 215 bits (525), Expect = 1e-55
Identities = 101/194 (52%), Positives = 141/194 (72%), Gaps = 2/194 (1%)
Frame = +1
Query: 91 IPLLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWF 270
+ LL E+ + T ALRA+GNIVTGTDEQTQVV++ AL+ FP+LLT+PK I KEA W
Sbjct: 299 VKLLGASELPIVTPALRAIGNIVTGTDEQTQVVIDAGALAVFPSLLTNPKTNIQKEATWT 358
Query: 271 LSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALIN 450
+SNITAG + Q+Q V++ GL+P +V+ LSK +F+TQKEA WAV+N + GT +Q+ L++
Sbjct: 359 MSNITAGRQDQIQQVVNHGLVPFLVSVLSKADFKTQKEAVWAVTNYTSGGTVEQIVYLVH 418
Query: 451 CGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAG--DNAEQVANMIEECGGIDKIEDLQT 624
CG+I P NLL+ KDT++I V+LD +SN+ + A E+++ MIEECGG+DKIE LQ
Sbjct: 419 CGIIEPLMNLLTAKDTKIILVILDAISNIFQAAEKLGETEKLSIMIEECGGLDKIEALQN 478
Query: 625 HXKMEIYKMAYDII 666
H +YK + +I
Sbjct: 479 HENESVYKASLSLI 492
Score = 80.2 bits (189), Expect = 6e-15
Identities = 52/192 (27%), Positives = 95/192 (49%)
Frame = +1
Query: 91 IPLLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWF 270
+ LL H + +V A+ + G +E+ +V+ + LL + I A+
Sbjct: 257 VRLLHHDDPEVLADTCWAISYLTDGPNERIGMVVKTGVVPQLVKLLGASELPIVTPALRA 316
Query: 271 LSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALIN 450
+ NI G +Q Q VIDAG L + + L+ + QKEA W +SN++ +G +DQ+ ++N
Sbjct: 317 IGNIVTGTDEQTQVVIDAGALAVFPSLLTNPKTNIQKEATWTMSNIT-AGRQDQIQQVVN 375
Query: 451 CGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGDNAEQVANMIEECGGIDKIEDLQTHX 630
G++P ++LS D + + ++N +G EQ+ ++ CG I+ + +L T
Sbjct: 376 HGLVPFLVSVLSKADFKTQKEAVWAVTNY--TSGGTVEQIVYLV-HCGIIEPLMNLLTAK 432
Query: 631 KMEIYKMAYDII 666
+I + D I
Sbjct: 433 DTKIILVILDAI 444
Score = 47.6 bits (108), Expect = 4e-05
Identities = 25/82 (30%), Positives = 43/82 (52%), Gaps = 2/82 (2%)
Frame = +1
Query: 256 EAVWFLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGT--RD 429
E+ W L+NI +G +Q +AV+D G + ++ L+ ++ WA+ N++ G+ RD
Sbjct: 139 ESAWALTNIASGTSEQTKAVVDGGAIRAFISLLASPHAHISEQDVWALGNIAGDGSVFRD 198
Query: 430 QVAALINCGVIPPFCNLLSCKD 495
V I G + P LL+ D
Sbjct: 199 LV---IKYGAVDPLLALLAVPD 217
Score = 46.8 bits (106), Expect = 7e-05
Identities = 30/101 (29%), Positives = 49/101 (48%), Gaps = 5/101 (4%)
Frame = +1
Query: 121 VQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWFLSNITAGNKQ 300
+Q + A+ NI +GT EQT+ V++ A+ F +LL P I ++ VW L NI
Sbjct: 136 IQFESAWALTNIASGTSEQTKAVVDGGAIRAFISLLASPHAHISEQDVWALGNIAGDGSV 195
Query: 301 QVQAVIDAGLLPMIVANLSKGEFQT-----QKEAAWAVSNL 408
VI G + ++A L+ + + + W +SNL
Sbjct: 196 FRDLVIKYGAVDPLLALLAVPDMSSLACGYLRNLTWTLSNL 236
Score = 42.3 bits (95), Expect = 0.001
Identities = 19/35 (54%), Positives = 25/35 (71%)
Frame = +3
Query: 3 DTVWAISYLTXGGNEQIQMVIXSGIVTTLXSVVVA 107
DT WAISYLT G NE+I MV+ +G+V L ++ A
Sbjct: 270 DTCWAISYLTDGPNERIGMVVKTGVVPQLVKLLGA 304
Score = 31.9 bits (69), Expect = 2.1
Identities = 13/33 (39%), Positives = 20/33 (60%)
Frame = +3
Query: 3 DTVWAISYLTXGGNEQIQMVIXSGIVTTLXSVV 101
+ W +S +T G +QIQ V+ G+V L SV+
Sbjct: 354 EATWTMSNITAGRQDQIQQVVNHGLVPFLVSVL 386
Score = 29.9 bits (64), Expect = 8.5
Identities = 13/40 (32%), Positives = 25/40 (62%), Gaps = 1/40 (2%)
Frame = +3
Query: 3 DTVWAISYLTXGGN-EQIQMVIXSGIVTTLXSVVVAQGSE 119
+ VWA++ T GG EQI ++ GI+ L +++ A+ ++
Sbjct: 396 EAVWAVTNYTSGGTVEQIVYLVHCGIIEPLMNLLTAKDTK 435
>BC053343-1|AAH53343.1| 529|Homo sapiens karyopherin alpha 2 (RAG
cohort 1, importin alpha 1) protein.
Length = 529
Score = 215 bits (525), Expect = 1e-55
Identities = 101/194 (52%), Positives = 141/194 (72%), Gaps = 2/194 (1%)
Frame = +1
Query: 91 IPLLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWF 270
+ LL E+ + T ALRA+GNIVTGTDEQTQVV++ AL+ FP+LLT+PK I KEA W
Sbjct: 299 VKLLGASELPIVTPALRAIGNIVTGTDEQTQVVIDAGALAVFPSLLTNPKTNIQKEATWT 358
Query: 271 LSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALIN 450
+SNITAG + Q+Q V++ GL+P +V+ LSK +F+TQKEA WAV+N + GT +Q+ L++
Sbjct: 359 MSNITAGRQDQIQQVVNHGLVPFLVSVLSKADFKTQKEAVWAVTNYTSGGTVEQIVYLVH 418
Query: 451 CGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAG--DNAEQVANMIEECGGIDKIEDLQT 624
CG+I P NLL+ KDT++I V+LD +SN+ + A E+++ MIEECGG+DKIE LQ
Sbjct: 419 CGIIEPLMNLLTAKDTKIILVILDAISNIFQAAEKLGETEKLSIMIEECGGLDKIEALQN 478
Query: 625 HXKMEIYKMAYDII 666
H +YK + +I
Sbjct: 479 HENESVYKASLSLI 492
Score = 80.2 bits (189), Expect = 6e-15
Identities = 52/192 (27%), Positives = 95/192 (49%)
Frame = +1
Query: 91 IPLLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWF 270
+ LL H + +V A+ + G +E+ +V+ + LL + I A+
Sbjct: 257 VRLLHHDDPEVLADTCWAISYLTDGPNERIGMVVKTGVVPQLVKLLGASELPIVTPALRA 316
Query: 271 LSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALIN 450
+ NI G +Q Q VIDAG L + + L+ + QKEA W +SN++ +G +DQ+ ++N
Sbjct: 317 IGNIVTGTDEQTQVVIDAGALAVFPSLLTNPKTNIQKEATWTMSNIT-AGRQDQIQQVVN 375
Query: 451 CGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGDNAEQVANMIEECGGIDKIEDLQTHX 630
G++P ++LS D + + ++N +G EQ+ ++ CG I+ + +L T
Sbjct: 376 HGLVPFLVSVLSKADFKTQKEAVWAVTNY--TSGGTVEQIVYLV-HCGIIEPLMNLLTAK 432
Query: 631 KMEIYKMAYDII 666
+I + D I
Sbjct: 433 DTKIILVILDAI 444
Score = 53.6 bits (123), Expect = 6e-07
Identities = 47/195 (24%), Positives = 83/195 (42%), Gaps = 7/195 (3%)
Frame = +1
Query: 91 IPLLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPK--EKIC---K 255
I LL+ + A+ A+GNI +V+ A+ ALL P+ C +
Sbjct: 168 ISLLASPHAHISEQAVWALGNIAGDGSVFRDLVIKYGAVDPLLALLAVPEMSSLACGYLR 227
Query: 256 EAVWFLSNITAGNKQQVQAVIDA--GLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRD 429
W LSN+ NK IDA +LP +V L + + + WA+S L+ G +
Sbjct: 228 NLTWTLSNL-CRNKNPAPP-IDAVEQILPTLVRLLHHDDPEVLADTCWAISYLT-DGPNE 284
Query: 430 QVAALINCGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGDNAEQVANMIEECGGIDKI 609
++ ++ GV+P LL + ++ L + N++ ++ ++ + G +
Sbjct: 285 RIGMVVKTGVVPQLVKLLGASELPIVTPALRAIGNIV----TGTDEQTQVVIDAGALAVF 340
Query: 610 EDLQTHXKMEIYKMA 654
L T+ K I K A
Sbjct: 341 PSLLTNPKTNIQKEA 355
Score = 52.0 bits (119), Expect = 2e-06
Identities = 26/79 (32%), Positives = 44/79 (55%), Gaps = 2/79 (2%)
Frame = +1
Query: 256 EAVWFLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGT--RD 429
E+ W L+NI +G +Q +AV+D G +P ++ L+ ++A WA+ N++ G+ RD
Sbjct: 139 ESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSVFRD 198
Query: 430 QVAALINCGVIPPFCNLLS 486
V I G + P LL+
Sbjct: 199 LV---IKYGAVDPLLALLA 214
Score = 50.4 bits (115), Expect = 6e-06
Identities = 31/103 (30%), Positives = 58/103 (56%), Gaps = 1/103 (0%)
Frame = +1
Query: 304 VQAVIDAGLLPMIVANLSKGEFQT-QKEAAWAVSNLSISGTRDQVAALINCGVIPPFCNL 480
+ +I AGL+P V+ L + + Q E+AWA++N++ SGT +Q A+++ G IP F +L
Sbjct: 112 IDNIIRAGLIPKFVSFLGRTDCSPIQFESAWALTNIA-SGTSEQTKAVVDGGAIPAFISL 170
Query: 481 LSCKDTQVINVVLDGLSNMLKMAGDNAEQVANMIEECGGIDKI 609
L+ + + L N +AGD + +++ + G +D +
Sbjct: 171 LASPHAHISEQAVWALGN---IAGDGS-VFRDLVIKYGAVDPL 209
Score = 50.4 bits (115), Expect = 6e-06
Identities = 32/101 (31%), Positives = 50/101 (49%), Gaps = 5/101 (4%)
Frame = +1
Query: 121 VQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWFLSNITAGNKQ 300
+Q + A+ NI +GT EQT+ V++ A+ F +LL P I ++AVW L NI
Sbjct: 136 IQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSV 195
Query: 301 QVQAVIDAGLLPMIVANLSKGEFQT-----QKEAAWAVSNL 408
VI G + ++A L+ E + + W +SNL
Sbjct: 196 FRDLVIKYGAVDPLLALLAVPEMSSLACGYLRNLTWTLSNL 236
Score = 42.3 bits (95), Expect = 0.001
Identities = 19/35 (54%), Positives = 25/35 (71%)
Frame = +3
Query: 3 DTVWAISYLTXGGNEQIQMVIXSGIVTTLXSVVVA 107
DT WAISYLT G NE+I MV+ +G+V L ++ A
Sbjct: 270 DTCWAISYLTDGPNERIGMVVKTGVVPQLVKLLGA 304
Score = 31.9 bits (69), Expect = 2.1
Identities = 13/33 (39%), Positives = 20/33 (60%)
Frame = +3
Query: 3 DTVWAISYLTXGGNEQIQMVIXSGIVTTLXSVV 101
+ W +S +T G +QIQ V+ G+V L SV+
Sbjct: 354 EATWTMSNITAGRQDQIQQVVNHGLVPFLVSVL 386
Score = 29.9 bits (64), Expect = 8.5
Identities = 13/40 (32%), Positives = 25/40 (62%), Gaps = 1/40 (2%)
Frame = +3
Query: 3 DTVWAISYLTXGGN-EQIQMVIXSGIVTTLXSVVVAQGSE 119
+ VWA++ T GG EQI ++ GI+ L +++ A+ ++
Sbjct: 396 EAVWAVTNYTSGGTVEQIVYLVHCGIIEPLMNLLTAKDTK 435
>AJ303086-1|CAC83080.1| 529|Homo sapiens karyopherin alpha 2
protein.
Length = 529
Score = 215 bits (525), Expect = 1e-55
Identities = 101/194 (52%), Positives = 141/194 (72%), Gaps = 2/194 (1%)
Frame = +1
Query: 91 IPLLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWF 270
+ LL E+ + T ALRA+GNIVTGTDEQTQVV++ AL+ FP+LLT+PK I KEA W
Sbjct: 299 VKLLGASELPIVTPALRAIGNIVTGTDEQTQVVIDAGALAVFPSLLTNPKTNIQKEATWT 358
Query: 271 LSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALIN 450
+SNITAG + Q+Q V++ GL+P +V+ LSK +F+TQKEA WAV+N + GT +Q+ L++
Sbjct: 359 MSNITAGRQDQIQQVVNHGLVPFLVSVLSKADFKTQKEAVWAVTNYTSGGTVEQIVYLVH 418
Query: 451 CGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAG--DNAEQVANMIEECGGIDKIEDLQT 624
CG+I P NLL+ KDT++I V+LD +SN+ + A E+++ MIEECGG+DKIE LQ
Sbjct: 419 CGIIEPLMNLLTAKDTKIILVILDAISNIFQAAEKLGETEKLSIMIEECGGLDKIEALQN 478
Query: 625 HXKMEIYKMAYDII 666
H +YK + +I
Sbjct: 479 HENESVYKASLSLI 492
Score = 80.2 bits (189), Expect = 6e-15
Identities = 52/192 (27%), Positives = 95/192 (49%)
Frame = +1
Query: 91 IPLLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWF 270
+ LL H + +V A+ + G +E+ +V+ + LL + I A+
Sbjct: 257 VRLLHHDDPEVLADTCWAISYLTDGPNERIGMVVKTGVVPQLVKLLGASELPIVTPALRA 316
Query: 271 LSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALIN 450
+ NI G +Q Q VIDAG L + + L+ + QKEA W +SN++ +G +DQ+ ++N
Sbjct: 317 IGNIVTGTDEQTQVVIDAGALAVFPSLLTNPKTNIQKEATWTMSNIT-AGRQDQIQQVVN 375
Query: 451 CGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGDNAEQVANMIEECGGIDKIEDLQTHX 630
G++P ++LS D + + ++N +G EQ+ ++ CG I+ + +L T
Sbjct: 376 HGLVPFLVSVLSKADFKTQKEAVWAVTNY--TSGGTVEQIVYLV-HCGIIEPLMNLLTAK 432
Query: 631 KMEIYKMAYDII 666
+I + D I
Sbjct: 433 DTKIILVILDAI 444
Score = 53.6 bits (123), Expect = 6e-07
Identities = 27/82 (32%), Positives = 45/82 (54%), Gaps = 2/82 (2%)
Frame = +1
Query: 256 EAVWFLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGT--RD 429
E+ W L+NI +G +Q +AV+D G +P ++ L+ ++A WA+ N++ G+ RD
Sbjct: 139 ESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSVFRD 198
Query: 430 QVAALINCGVIPPFCNLLSCKD 495
V I G + P LL+ D
Sbjct: 199 LV---IKYGAVDPLLALLAVPD 217
Score = 53.2 bits (122), Expect = 8e-07
Identities = 47/195 (24%), Positives = 82/195 (42%), Gaps = 7/195 (3%)
Frame = +1
Query: 91 IPLLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHP--KEKIC---K 255
I LL+ + A+ A+GNI +V+ A+ ALL P C +
Sbjct: 168 ISLLASPHAHISEQAVWALGNIAGDGSVFRDLVIKYGAVDPLLALLAVPDMSSLACGYLR 227
Query: 256 EAVWFLSNITAGNKQQVQAVIDA--GLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRD 429
W LSN+ NK IDA +LP +V L + + + WA+S L+ G +
Sbjct: 228 NLTWTLSNL-CRNKNPAPP-IDAVEQILPTLVRLLHHDDPEVLADTCWAISYLT-DGPNE 284
Query: 430 QVAALINCGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGDNAEQVANMIEECGGIDKI 609
++ ++ GV+P LL + ++ L + N++ ++ ++ + G +
Sbjct: 285 RIGMVVKTGVVPQLVKLLGASELPIVTPALRAIGNIV----TGTDEQTQVVIDAGALAVF 340
Query: 610 EDLQTHXKMEIYKMA 654
L T+ K I K A
Sbjct: 341 PSLLTNPKTNIQKEA 355
Score = 50.4 bits (115), Expect = 6e-06
Identities = 31/103 (30%), Positives = 58/103 (56%), Gaps = 1/103 (0%)
Frame = +1
Query: 304 VQAVIDAGLLPMIVANLSKGEFQT-QKEAAWAVSNLSISGTRDQVAALINCGVIPPFCNL 480
+ +I AGL+P V+ L + + Q E+AWA++N++ SGT +Q A+++ G IP F +L
Sbjct: 112 IDNIIRAGLIPKFVSFLGRTDCSPIQFESAWALTNIA-SGTSEQTKAVVDGGAIPAFISL 170
Query: 481 LSCKDTQVINVVLDGLSNMLKMAGDNAEQVANMIEECGGIDKI 609
L+ + + L N +AGD + +++ + G +D +
Sbjct: 171 LASPHAHISEQAVWALGN---IAGDGS-VFRDLVIKYGAVDPL 209
Score = 49.2 bits (112), Expect = 1e-05
Identities = 31/101 (30%), Positives = 50/101 (49%), Gaps = 5/101 (4%)
Frame = +1
Query: 121 VQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWFLSNITAGNKQ 300
+Q + A+ NI +GT EQT+ V++ A+ F +LL P I ++AVW L NI
Sbjct: 136 IQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSV 195
Query: 301 QVQAVIDAGLLPMIVANLSKGEFQT-----QKEAAWAVSNL 408
VI G + ++A L+ + + + W +SNL
Sbjct: 196 FRDLVIKYGAVDPLLALLAVPDMSSLACGYLRNLTWTLSNL 236
Score = 42.3 bits (95), Expect = 0.001
Identities = 19/35 (54%), Positives = 25/35 (71%)
Frame = +3
Query: 3 DTVWAISYLTXGGNEQIQMVIXSGIVTTLXSVVVA 107
DT WAISYLT G NE+I MV+ +G+V L ++ A
Sbjct: 270 DTCWAISYLTDGPNERIGMVVKTGVVPQLVKLLGA 304
Score = 31.9 bits (69), Expect = 2.1
Identities = 13/33 (39%), Positives = 20/33 (60%)
Frame = +3
Query: 3 DTVWAISYLTXGGNEQIQMVIXSGIVTTLXSVV 101
+ W +S +T G +QIQ V+ G+V L SV+
Sbjct: 354 EATWTMSNITAGRQDQIQQVVNHGLVPFLVSVL 386
Score = 29.9 bits (64), Expect = 8.5
Identities = 13/40 (32%), Positives = 25/40 (62%), Gaps = 1/40 (2%)
Frame = +3
Query: 3 DTVWAISYLTXGGN-EQIQMVIXSGIVTTLXSVVVAQGSE 119
+ VWA++ T GG EQI ++ GI+ L +++ A+ ++
Sbjct: 396 EAVWAVTNYTSGGTVEQIVYLVHCGIIEPLMNLLTAKDTK 435
>BT009843-1|AAP88845.1| 536|Homo sapiens karyopherin alpha 6
(importin alpha 7) protein.
Length = 536
Score = 203 bits (495), Expect = 5e-52
Identities = 99/199 (49%), Positives = 135/199 (67%), Gaps = 7/199 (3%)
Frame = +1
Query: 91 IPLLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWF 270
+ LL H + KV + ALRAVGNIVTG D QTQV+LNC AL LL+ PKE I KEA W
Sbjct: 300 VELLMHNDYKVASPALRAVGNIVTGDDIQTQVILNCSALPCLLHLLSSPKESIRKEACWT 359
Query: 271 LSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALIN 450
+SNITAGN+ Q+QAVIDA + P+++ L K EF+T+KEAAWA++N + GT +Q+ L++
Sbjct: 360 ISNITAGNRAQIQAVIDANIFPVLIEILQKAEFRTRKEAAWAITNATSGGTPEQIRYLVS 419
Query: 451 CGVIPPFCNLLSCKDTQVINVVLDGLSNML-------KMAGDNAEQVANMIEECGGIDKI 609
G I P C+LL+ D++++ V L+GL N+L K +G +IEE G+DKI
Sbjct: 420 LGCIKPLCDLLTVMDSKIVQVALNGLENILRLGEQEGKRSGSGVNPYCGLIEEAYGLDKI 479
Query: 610 EDLQTHXKMEIYKMAYDII 666
E LQ+H EIY+ A+D+I
Sbjct: 480 EFLQSHENQEIYQKAFDLI 498
Score = 67.3 bits (157), Expect = 5e-11
Identities = 48/194 (24%), Positives = 90/194 (46%), Gaps = 4/194 (2%)
Frame = +1
Query: 85 PXIPLLSH----KEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKIC 252
P +P+LS + + A A+ + G +E+ Q V++ LL H K+
Sbjct: 252 PCLPVLSRLLFSSDSDLLADACWALSYLSDGPNEKIQAVIDSGVCRRLVELLMHNDYKVA 311
Query: 253 KEAVWFLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQ 432
A+ + NI G+ Q Q +++ LP ++ LS + +KEA W +SN++ +G R Q
Sbjct: 312 SPALRAVGNIVTGDDIQTQVILNCSALPCLLHLLSSPKESIRKEACWTISNIT-AGNRAQ 370
Query: 433 VAALINCGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGDNAEQVANMIEECGGIDKIE 612
+ A+I+ + P +L + + ++N +G EQ+ ++ G I +
Sbjct: 371 IQAVIDANIFPVLIEILQKAEFRTRKEAAWAITN--ATSGGTPEQIRYLV-SLGCIKPLC 427
Query: 613 DLQTHXKMEIYKMA 654
DL T +I ++A
Sbjct: 428 DLLTVMDSKIVQVA 441
Score = 64.9 bits (151), Expect = 2e-10
Identities = 54/189 (28%), Positives = 86/189 (45%), Gaps = 1/189 (0%)
Frame = +1
Query: 91 IPLLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLT-HPKEKICKEAVW 267
I LL+ VQ A+ A+GNI + VLNC L+ LLT + + + AVW
Sbjct: 173 IELLNSDFEDVQEQAVWALGNIAGDSSVCRDYVLNCSILNPLLTLLTKSTRLTMTRNAVW 232
Query: 268 FLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALI 447
LSN+ G + + LP++ L + +A WA+S LS G +++ A+I
Sbjct: 233 ALSNLCRGKNPPPEFAKVSPCLPVLSRLLFSSDSDLLADACWALSYLS-DGPNEKIQAVI 291
Query: 448 NCGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGDNAEQVANMIEECGGIDKIEDLQTH 627
+ GV LL D +V + L + N+ + GD+ + +I C + + L +
Sbjct: 292 DSGVCRRLVELLMHNDYKVASPALRAVGNI--VTGDDIQ--TQVILNCSALPCLLHLLSS 347
Query: 628 XKMEIYKMA 654
K I K A
Sbjct: 348 PKESIRKEA 356
Score = 58.0 bits (134), Expect = 3e-08
Identities = 36/100 (36%), Positives = 55/100 (55%), Gaps = 4/100 (4%)
Frame = +1
Query: 256 EAVWFLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLS--ISGTRD 429
EA W L+NI +G QQ + VI+AG +P+ + L+ Q++A WA+ N++ S RD
Sbjct: 144 EAAWALTNIASGTSQQTKIVIEAGAVPIFIELLNSDFEDVQEQAVWALGNIAGDSSVCRD 203
Query: 430 QVAALINCGVIPPFCNLL--SCKDTQVINVVLDGLSNMLK 543
V +NC ++ P LL S + T N V LSN+ +
Sbjct: 204 YV---LNCSILNPLLTLLTKSTRLTMTRNAVW-ALSNLCR 239
Score = 56.8 bits (131), Expect = 7e-08
Identities = 41/161 (25%), Positives = 73/161 (45%), Gaps = 1/161 (0%)
Frame = +1
Query: 85 PXIPLLSHKEVKVQTA-ALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEA 261
P + LL+ T A+ A+ N+ G + + L LL + +A
Sbjct: 213 PLLTLLTKSTRLTMTRNAVWALSNLCRGKNPPPEFAKVSPCLPVLSRLLFSSDSDLLADA 272
Query: 262 VWFLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAA 441
W LS ++ G +++QAVID+G+ +V L +++ A AV N+ ++G Q
Sbjct: 273 CWALSYLSDGPNEKIQAVIDSGVCRRLVELLMHNDYKVASPALRAVGNI-VTGDDIQTQV 331
Query: 442 LINCGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGDNAE 564
++NC +P +LLS + +SN+ AG+ A+
Sbjct: 332 ILNCSALPCLLHLLSSPKESIRKEACWTISNI--TAGNRAQ 370
Score = 55.2 bits (127), Expect = 2e-07
Identities = 33/105 (31%), Positives = 55/105 (52%), Gaps = 1/105 (0%)
Frame = +1
Query: 97 LLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWFLS 276
L ++ +Q A A+ NI +GT +QT++V+ A+ F LL E + ++AVW L
Sbjct: 133 LKRNENCTLQFEAAWALTNIASGTSQQTKIVIEAGAVPIFIELLNSDFEDVQEQAVWALG 192
Query: 277 NITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQ-KEAAWAVSNL 408
NI + V++ +L ++ L+K T + A WA+SNL
Sbjct: 193 NIAGDSSVCRDYVLNCSILNPLLTLLTKSTRLTMTRNAVWALSNL 237
Score = 37.9 bits (84), Expect = 0.032
Identities = 16/34 (47%), Positives = 23/34 (67%)
Frame = +3
Query: 3 DTVWAISYLTXGGNEQIQMVIXSGIVTTLXSVVV 104
D WA+SYL+ G NE+IQ VI SG+ L +++
Sbjct: 271 DACWALSYLSDGPNEKIQAVIDSGVCRRLVELLM 304
Score = 37.5 bits (83), Expect = 0.043
Identities = 23/62 (37%), Positives = 34/62 (54%)
Frame = +1
Query: 376 QKEAAWAVSNLSISGTRDQVAALINCGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGD 555
Q EAAWA++N++ SGT Q +I G +P F LL+ V + L N +AGD
Sbjct: 142 QFEAAWALTNIA-SGTSQQTKIVIEAGAVPIFIELLNSDFEDVQEQAVWALGN---IAGD 197
Query: 556 NA 561
++
Sbjct: 198 SS 199
>BC020520-1|AAH20520.1| 536|Homo sapiens karyopherin alpha 6
(importin alpha 7) protein.
Length = 536
Score = 203 bits (495), Expect = 5e-52
Identities = 99/199 (49%), Positives = 135/199 (67%), Gaps = 7/199 (3%)
Frame = +1
Query: 91 IPLLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWF 270
+ LL H + KV + ALRAVGNIVTG D QTQV+LNC AL LL+ PKE I KEA W
Sbjct: 300 VELLMHNDYKVASPALRAVGNIVTGDDIQTQVILNCSALPCLLHLLSSPKESIRKEACWT 359
Query: 271 LSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALIN 450
+SNITAGN+ Q+QAVIDA + P+++ L K EF+T+KEAAWA++N + GT +Q+ L++
Sbjct: 360 ISNITAGNRAQIQAVIDANIFPVLIEILQKAEFRTRKEAAWAITNATSGGTPEQIRYLVS 419
Query: 451 CGVIPPFCNLLSCKDTQVINVVLDGLSNML-------KMAGDNAEQVANMIEECGGIDKI 609
G I P C+LL+ D++++ V L+GL N+L K +G +IEE G+DKI
Sbjct: 420 LGCIKPLCDLLTVMDSKIVQVALNGLENILRLGEQEGKRSGSGVNPYCGLIEEAYGLDKI 479
Query: 610 EDLQTHXKMEIYKMAYDII 666
E LQ+H EIY+ A+D+I
Sbjct: 480 EFLQSHENQEIYQKAFDLI 498
Score = 67.3 bits (157), Expect = 5e-11
Identities = 48/194 (24%), Positives = 90/194 (46%), Gaps = 4/194 (2%)
Frame = +1
Query: 85 PXIPLLSH----KEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKIC 252
P +P+LS + + A A+ + G +E+ Q V++ LL H K+
Sbjct: 252 PCLPVLSRLLFSSDSDLLADACWALSYLSDGPNEKIQAVIDSGVCRRLVELLMHNDYKVA 311
Query: 253 KEAVWFLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQ 432
A+ + NI G+ Q Q +++ LP ++ LS + +KEA W +SN++ +G R Q
Sbjct: 312 SPALRAVGNIVTGDDIQTQVILNCSALPCLLHLLSSPKESIRKEACWTISNIT-AGNRAQ 370
Query: 433 VAALINCGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGDNAEQVANMIEECGGIDKIE 612
+ A+I+ + P +L + + ++N +G EQ+ ++ G I +
Sbjct: 371 IQAVIDANIFPVLIEILQKAEFRTRKEAAWAITN--ATSGGTPEQIRYLV-SLGCIKPLC 427
Query: 613 DLQTHXKMEIYKMA 654
DL T +I ++A
Sbjct: 428 DLLTVMDSKIVQVA 441
Score = 64.9 bits (151), Expect = 2e-10
Identities = 54/189 (28%), Positives = 86/189 (45%), Gaps = 1/189 (0%)
Frame = +1
Query: 91 IPLLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLT-HPKEKICKEAVW 267
I LL+ VQ A+ A+GNI + VLNC L+ LLT + + + AVW
Sbjct: 173 IELLNSDFEDVQEQAVWALGNIAGDSSVCRDYVLNCSILNPLLTLLTKSTRLTMTRNAVW 232
Query: 268 FLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALI 447
LSN+ G + + LP++ L + +A WA+S LS G +++ A+I
Sbjct: 233 ALSNLCRGKNPPPEFAKVSPCLPVLSRLLFSSDSDLLADACWALSYLS-DGPNEKIQAVI 291
Query: 448 NCGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGDNAEQVANMIEECGGIDKIEDLQTH 627
+ GV LL D +V + L + N+ + GD+ + +I C + + L +
Sbjct: 292 DSGVCRRLVELLMHNDYKVASPALRAVGNI--VTGDDIQ--TQVILNCSALPCLLHLLSS 347
Query: 628 XKMEIYKMA 654
K I K A
Sbjct: 348 PKESIRKEA 356
Score = 58.0 bits (134), Expect = 3e-08
Identities = 36/100 (36%), Positives = 55/100 (55%), Gaps = 4/100 (4%)
Frame = +1
Query: 256 EAVWFLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLS--ISGTRD 429
EA W L+NI +G QQ + VI+AG +P+ + L+ Q++A WA+ N++ S RD
Sbjct: 144 EAAWALTNIASGTSQQTKIVIEAGAVPIFIELLNSDFEDVQEQAVWALGNIAGDSSVCRD 203
Query: 430 QVAALINCGVIPPFCNLL--SCKDTQVINVVLDGLSNMLK 543
V +NC ++ P LL S + T N V LSN+ +
Sbjct: 204 YV---LNCSILNPLLTLLTKSTRLTMTRNAVW-ALSNLCR 239
Score = 56.8 bits (131), Expect = 7e-08
Identities = 41/161 (25%), Positives = 73/161 (45%), Gaps = 1/161 (0%)
Frame = +1
Query: 85 PXIPLLSHKEVKVQTA-ALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEA 261
P + LL+ T A+ A+ N+ G + + L LL + +A
Sbjct: 213 PLLTLLTKSTRLTMTRNAVWALSNLCRGKNPPPEFAKVSPCLPVLSRLLFSSDSDLLADA 272
Query: 262 VWFLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAA 441
W LS ++ G +++QAVID+G+ +V L +++ A AV N+ ++G Q
Sbjct: 273 CWALSYLSDGPNEKIQAVIDSGVCRRLVELLMHNDYKVASPALRAVGNI-VTGDDIQTQV 331
Query: 442 LINCGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGDNAE 564
++NC +P +LLS + +SN+ AG+ A+
Sbjct: 332 ILNCSALPCLLHLLSSPKESIRKEACWTISNI--TAGNRAQ 370
Score = 55.2 bits (127), Expect = 2e-07
Identities = 33/105 (31%), Positives = 55/105 (52%), Gaps = 1/105 (0%)
Frame = +1
Query: 97 LLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWFLS 276
L ++ +Q A A+ NI +GT +QT++V+ A+ F LL E + ++AVW L
Sbjct: 133 LKRNENCTLQFEAAWALTNIASGTSQQTKIVIEAGAVPIFIELLNSDFEDVQEQAVWALG 192
Query: 277 NITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQ-KEAAWAVSNL 408
NI + V++ +L ++ L+K T + A WA+SNL
Sbjct: 193 NIAGDSSVCRDYVLNCSILNPLLTLLTKSTRLTMTRNAVWALSNL 237
Score = 37.9 bits (84), Expect = 0.032
Identities = 16/34 (47%), Positives = 23/34 (67%)
Frame = +3
Query: 3 DTVWAISYLTXGGNEQIQMVIXSGIVTTLXSVVV 104
D WA+SYL+ G NE+IQ VI SG+ L +++
Sbjct: 271 DACWALSYLSDGPNEKIQAVIDSGVCRRLVELLM 304
Score = 37.5 bits (83), Expect = 0.043
Identities = 23/62 (37%), Positives = 34/62 (54%)
Frame = +1
Query: 376 QKEAAWAVSNLSISGTRDQVAALINCGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGD 555
Q EAAWA++N++ SGT Q +I G +P F LL+ V + L N +AGD
Sbjct: 142 QFEAAWALTNIA-SGTSQQTKIVIEAGAVPIFIELLNSDFEDVQEQAVWALGN---IAGD 197
Query: 556 NA 561
++
Sbjct: 198 SS 199
>AL445248-5|CAH71948.1| 536|Homo sapiens karyopherin alpha 6
(importin alpha 7) protein.
Length = 536
Score = 203 bits (495), Expect = 5e-52
Identities = 99/199 (49%), Positives = 135/199 (67%), Gaps = 7/199 (3%)
Frame = +1
Query: 91 IPLLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWF 270
+ LL H + KV + ALRAVGNIVTG D QTQV+LNC AL LL+ PKE I KEA W
Sbjct: 300 VELLMHNDYKVASPALRAVGNIVTGDDIQTQVILNCSALPCLLHLLSSPKESIRKEACWT 359
Query: 271 LSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALIN 450
+SNITAGN+ Q+QAVIDA + P+++ L K EF+T+KEAAWA++N + GT +Q+ L++
Sbjct: 360 ISNITAGNRAQIQAVIDANIFPVLIEILQKAEFRTRKEAAWAITNATSGGTPEQIRYLVS 419
Query: 451 CGVIPPFCNLLSCKDTQVINVVLDGLSNML-------KMAGDNAEQVANMIEECGGIDKI 609
G I P C+LL+ D++++ V L+GL N+L K +G +IEE G+DKI
Sbjct: 420 LGCIKPLCDLLTVMDSKIVQVALNGLENILRLGEQEGKRSGSGVNPYCGLIEEAYGLDKI 479
Query: 610 EDLQTHXKMEIYKMAYDII 666
E LQ+H EIY+ A+D+I
Sbjct: 480 EFLQSHENQEIYQKAFDLI 498
Score = 67.3 bits (157), Expect = 5e-11
Identities = 48/194 (24%), Positives = 90/194 (46%), Gaps = 4/194 (2%)
Frame = +1
Query: 85 PXIPLLSH----KEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKIC 252
P +P+LS + + A A+ + G +E+ Q V++ LL H K+
Sbjct: 252 PCLPVLSRLLFSSDSDLLADACWALSYLSDGPNEKIQAVIDSGVCRRLVELLMHNDYKVA 311
Query: 253 KEAVWFLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQ 432
A+ + NI G+ Q Q +++ LP ++ LS + +KEA W +SN++ +G R Q
Sbjct: 312 SPALRAVGNIVTGDDIQTQVILNCSALPCLLHLLSSPKESIRKEACWTISNIT-AGNRAQ 370
Query: 433 VAALINCGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGDNAEQVANMIEECGGIDKIE 612
+ A+I+ + P +L + + ++N +G EQ+ ++ G I +
Sbjct: 371 IQAVIDANIFPVLIEILQKAEFRTRKEAAWAITN--ATSGGTPEQIRYLV-SLGCIKPLC 427
Query: 613 DLQTHXKMEIYKMA 654
DL T +I ++A
Sbjct: 428 DLLTVMDSKIVQVA 441
Score = 64.9 bits (151), Expect = 2e-10
Identities = 54/189 (28%), Positives = 86/189 (45%), Gaps = 1/189 (0%)
Frame = +1
Query: 91 IPLLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLT-HPKEKICKEAVW 267
I LL+ VQ A+ A+GNI + VLNC L+ LLT + + + AVW
Sbjct: 173 IELLNSDFEDVQEQAVWALGNIAGDSSVCRDYVLNCSILNPLLTLLTKSTRLTMTRNAVW 232
Query: 268 FLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALI 447
LSN+ G + + LP++ L + +A WA+S LS G +++ A+I
Sbjct: 233 ALSNLCRGKNPPPEFAKVSPCLPVLSRLLFSSDSDLLADACWALSYLS-DGPNEKIQAVI 291
Query: 448 NCGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGDNAEQVANMIEECGGIDKIEDLQTH 627
+ GV LL D +V + L + N+ + GD+ + +I C + + L +
Sbjct: 292 DSGVCRRLVELLMHNDYKVASPALRAVGNI--VTGDDIQ--TQVILNCSALPCLLHLLSS 347
Query: 628 XKMEIYKMA 654
K I K A
Sbjct: 348 PKESIRKEA 356
Score = 58.0 bits (134), Expect = 3e-08
Identities = 36/100 (36%), Positives = 55/100 (55%), Gaps = 4/100 (4%)
Frame = +1
Query: 256 EAVWFLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLS--ISGTRD 429
EA W L+NI +G QQ + VI+AG +P+ + L+ Q++A WA+ N++ S RD
Sbjct: 144 EAAWALTNIASGTSQQTKIVIEAGAVPIFIELLNSDFEDVQEQAVWALGNIAGDSSVCRD 203
Query: 430 QVAALINCGVIPPFCNLL--SCKDTQVINVVLDGLSNMLK 543
V +NC ++ P LL S + T N V LSN+ +
Sbjct: 204 YV---LNCSILNPLLTLLTKSTRLTMTRNAVW-ALSNLCR 239
Score = 56.8 bits (131), Expect = 7e-08
Identities = 41/161 (25%), Positives = 73/161 (45%), Gaps = 1/161 (0%)
Frame = +1
Query: 85 PXIPLLSHKEVKVQTA-ALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEA 261
P + LL+ T A+ A+ N+ G + + L LL + +A
Sbjct: 213 PLLTLLTKSTRLTMTRNAVWALSNLCRGKNPPPEFAKVSPCLPVLSRLLFSSDSDLLADA 272
Query: 262 VWFLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAA 441
W LS ++ G +++QAVID+G+ +V L +++ A AV N+ ++G Q
Sbjct: 273 CWALSYLSDGPNEKIQAVIDSGVCRRLVELLMHNDYKVASPALRAVGNI-VTGDDIQTQV 331
Query: 442 LINCGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGDNAE 564
++NC +P +LLS + +SN+ AG+ A+
Sbjct: 332 ILNCSALPCLLHLLSSPKESIRKEACWTISNI--TAGNRAQ 370
Score = 55.2 bits (127), Expect = 2e-07
Identities = 33/105 (31%), Positives = 55/105 (52%), Gaps = 1/105 (0%)
Frame = +1
Query: 97 LLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWFLS 276
L ++ +Q A A+ NI +GT +QT++V+ A+ F LL E + ++AVW L
Sbjct: 133 LKRNENCTLQFEAAWALTNIASGTSQQTKIVIEAGAVPIFIELLNSDFEDVQEQAVWALG 192
Query: 277 NITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQ-KEAAWAVSNL 408
NI + V++ +L ++ L+K T + A WA+SNL
Sbjct: 193 NIAGDSSVCRDYVLNCSILNPLLTLLTKSTRLTMTRNAVWALSNL 237
Score = 37.9 bits (84), Expect = 0.032
Identities = 16/34 (47%), Positives = 23/34 (67%)
Frame = +3
Query: 3 DTVWAISYLTXGGNEQIQMVIXSGIVTTLXSVVV 104
D WA+SYL+ G NE+IQ VI SG+ L +++
Sbjct: 271 DACWALSYLSDGPNEKIQAVIDSGVCRRLVELLM 304
Score = 37.5 bits (83), Expect = 0.043
Identities = 23/62 (37%), Positives = 34/62 (54%)
Frame = +1
Query: 376 QKEAAWAVSNLSISGTRDQVAALINCGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGD 555
Q EAAWA++N++ SGT Q +I G +P F LL+ V + L N +AGD
Sbjct: 142 QFEAAWALTNIA-SGTSQQTKIVIEAGAVPIFIELLNSDFEDVQEQAVWALGN---IAGD 197
Query: 556 NA 561
++
Sbjct: 198 SS 199
>AL049795-3|CAI22056.1| 536|Homo sapiens karyopherin alpha 6
(importin alpha 7) protein.
Length = 536
Score = 203 bits (495), Expect = 5e-52
Identities = 99/199 (49%), Positives = 135/199 (67%), Gaps = 7/199 (3%)
Frame = +1
Query: 91 IPLLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWF 270
+ LL H + KV + ALRAVGNIVTG D QTQV+LNC AL LL+ PKE I KEA W
Sbjct: 300 VELLMHNDYKVASPALRAVGNIVTGDDIQTQVILNCSALPCLLHLLSSPKESIRKEACWT 359
Query: 271 LSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALIN 450
+SNITAGN+ Q+QAVIDA + P+++ L K EF+T+KEAAWA++N + GT +Q+ L++
Sbjct: 360 ISNITAGNRAQIQAVIDANIFPVLIEILQKAEFRTRKEAAWAITNATSGGTPEQIRYLVS 419
Query: 451 CGVIPPFCNLLSCKDTQVINVVLDGLSNML-------KMAGDNAEQVANMIEECGGIDKI 609
G I P C+LL+ D++++ V L+GL N+L K +G +IEE G+DKI
Sbjct: 420 LGCIKPLCDLLTVMDSKIVQVALNGLENILRLGEQEGKRSGSGVNPYCGLIEEAYGLDKI 479
Query: 610 EDLQTHXKMEIYKMAYDII 666
E LQ+H EIY+ A+D+I
Sbjct: 480 EFLQSHENQEIYQKAFDLI 498
Score = 67.3 bits (157), Expect = 5e-11
Identities = 48/194 (24%), Positives = 90/194 (46%), Gaps = 4/194 (2%)
Frame = +1
Query: 85 PXIPLLSH----KEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKIC 252
P +P+LS + + A A+ + G +E+ Q V++ LL H K+
Sbjct: 252 PCLPVLSRLLFSSDSDLLADACWALSYLSDGPNEKIQAVIDSGVCRRLVELLMHNDYKVA 311
Query: 253 KEAVWFLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQ 432
A+ + NI G+ Q Q +++ LP ++ LS + +KEA W +SN++ +G R Q
Sbjct: 312 SPALRAVGNIVTGDDIQTQVILNCSALPCLLHLLSSPKESIRKEACWTISNIT-AGNRAQ 370
Query: 433 VAALINCGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGDNAEQVANMIEECGGIDKIE 612
+ A+I+ + P +L + + ++N +G EQ+ ++ G I +
Sbjct: 371 IQAVIDANIFPVLIEILQKAEFRTRKEAAWAITN--ATSGGTPEQIRYLV-SLGCIKPLC 427
Query: 613 DLQTHXKMEIYKMA 654
DL T +I ++A
Sbjct: 428 DLLTVMDSKIVQVA 441
Score = 64.9 bits (151), Expect = 2e-10
Identities = 54/189 (28%), Positives = 86/189 (45%), Gaps = 1/189 (0%)
Frame = +1
Query: 91 IPLLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLT-HPKEKICKEAVW 267
I LL+ VQ A+ A+GNI + VLNC L+ LLT + + + AVW
Sbjct: 173 IELLNSDFEDVQEQAVWALGNIAGDSSVCRDYVLNCSILNPLLTLLTKSTRLTMTRNAVW 232
Query: 268 FLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALI 447
LSN+ G + + LP++ L + +A WA+S LS G +++ A+I
Sbjct: 233 ALSNLCRGKNPPPEFAKVSPCLPVLSRLLFSSDSDLLADACWALSYLS-DGPNEKIQAVI 291
Query: 448 NCGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGDNAEQVANMIEECGGIDKIEDLQTH 627
+ GV LL D +V + L + N+ + GD+ + +I C + + L +
Sbjct: 292 DSGVCRRLVELLMHNDYKVASPALRAVGNI--VTGDDIQ--TQVILNCSALPCLLHLLSS 347
Query: 628 XKMEIYKMA 654
K I K A
Sbjct: 348 PKESIRKEA 356
Score = 58.0 bits (134), Expect = 3e-08
Identities = 36/100 (36%), Positives = 55/100 (55%), Gaps = 4/100 (4%)
Frame = +1
Query: 256 EAVWFLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLS--ISGTRD 429
EA W L+NI +G QQ + VI+AG +P+ + L+ Q++A WA+ N++ S RD
Sbjct: 144 EAAWALTNIASGTSQQTKIVIEAGAVPIFIELLNSDFEDVQEQAVWALGNIAGDSSVCRD 203
Query: 430 QVAALINCGVIPPFCNLL--SCKDTQVINVVLDGLSNMLK 543
V +NC ++ P LL S + T N V LSN+ +
Sbjct: 204 YV---LNCSILNPLLTLLTKSTRLTMTRNAVW-ALSNLCR 239
Score = 56.8 bits (131), Expect = 7e-08
Identities = 41/161 (25%), Positives = 73/161 (45%), Gaps = 1/161 (0%)
Frame = +1
Query: 85 PXIPLLSHKEVKVQTA-ALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEA 261
P + LL+ T A+ A+ N+ G + + L LL + +A
Sbjct: 213 PLLTLLTKSTRLTMTRNAVWALSNLCRGKNPPPEFAKVSPCLPVLSRLLFSSDSDLLADA 272
Query: 262 VWFLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAA 441
W LS ++ G +++QAVID+G+ +V L +++ A AV N+ ++G Q
Sbjct: 273 CWALSYLSDGPNEKIQAVIDSGVCRRLVELLMHNDYKVASPALRAVGNI-VTGDDIQTQV 331
Query: 442 LINCGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGDNAE 564
++NC +P +LLS + +SN+ AG+ A+
Sbjct: 332 ILNCSALPCLLHLLSSPKESIRKEACWTISNI--TAGNRAQ 370
Score = 55.2 bits (127), Expect = 2e-07
Identities = 33/105 (31%), Positives = 55/105 (52%), Gaps = 1/105 (0%)
Frame = +1
Query: 97 LLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWFLS 276
L ++ +Q A A+ NI +GT +QT++V+ A+ F LL E + ++AVW L
Sbjct: 133 LKRNENCTLQFEAAWALTNIASGTSQQTKIVIEAGAVPIFIELLNSDFEDVQEQAVWALG 192
Query: 277 NITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQ-KEAAWAVSNL 408
NI + V++ +L ++ L+K T + A WA+SNL
Sbjct: 193 NIAGDSSVCRDYVLNCSILNPLLTLLTKSTRLTMTRNAVWALSNL 237
Score = 37.9 bits (84), Expect = 0.032
Identities = 16/34 (47%), Positives = 23/34 (67%)
Frame = +3
Query: 3 DTVWAISYLTXGGNEQIQMVIXSGIVTTLXSVVV 104
D WA+SYL+ G NE+IQ VI SG+ L +++
Sbjct: 271 DACWALSYLSDGPNEKIQAVIDSGVCRRLVELLM 304
Score = 37.5 bits (83), Expect = 0.043
Identities = 23/62 (37%), Positives = 34/62 (54%)
Frame = +1
Query: 376 QKEAAWAVSNLSISGTRDQVAALINCGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGD 555
Q EAAWA++N++ SGT Q +I G +P F LL+ V + L N +AGD
Sbjct: 142 QFEAAWALTNIA-SGTSQQTKIVIEAGAVPIFIELLNSDFEDVQEQAVWALGN---IAGD 197
Query: 556 NA 561
++
Sbjct: 198 SS 199
>AF060543-1|AAC15233.1| 536|Homo sapiens importin alpha 7 subunit
protein.
Length = 536
Score = 203 bits (495), Expect = 5e-52
Identities = 99/199 (49%), Positives = 135/199 (67%), Gaps = 7/199 (3%)
Frame = +1
Query: 91 IPLLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWF 270
+ LL H + KV + ALRAVGNIVTG D QTQV+LNC AL LL+ PKE I KEA W
Sbjct: 300 VELLMHNDYKVASPALRAVGNIVTGDDIQTQVILNCSALPCLLHLLSSPKESIRKEACWT 359
Query: 271 LSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALIN 450
+SNITAGN+ Q+QAVIDA + P+++ L K EF+T+KEAAWA++N + GT +Q+ L++
Sbjct: 360 ISNITAGNRAQIQAVIDANIFPVLIEILQKAEFRTRKEAAWAITNATSGGTPEQIRYLVS 419
Query: 451 CGVIPPFCNLLSCKDTQVINVVLDGLSNML-------KMAGDNAEQVANMIEECGGIDKI 609
G I P C+LL+ D++++ V L+GL N+L K +G +IEE G+DKI
Sbjct: 420 LGCIKPLCDLLTVMDSKIVQVALNGLENILRLGEQEGKRSGSGVNPYCGLIEEAYGLDKI 479
Query: 610 EDLQTHXKMEIYKMAYDII 666
E LQ+H EIY+ A+D+I
Sbjct: 480 EFLQSHENQEIYQKAFDLI 498
Score = 67.3 bits (157), Expect = 5e-11
Identities = 48/194 (24%), Positives = 90/194 (46%), Gaps = 4/194 (2%)
Frame = +1
Query: 85 PXIPLLSH----KEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKIC 252
P +P+LS + + A A+ + G +E+ Q V++ LL H K+
Sbjct: 252 PCLPVLSRLLFSSDSDLLADACWALSYLSDGPNEKIQAVIDSGVCRRLVELLMHNDYKVA 311
Query: 253 KEAVWFLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQ 432
A+ + NI G+ Q Q +++ LP ++ LS + +KEA W +SN++ +G R Q
Sbjct: 312 SPALRAVGNIVTGDDIQTQVILNCSALPCLLHLLSSPKESIRKEACWTISNIT-AGNRAQ 370
Query: 433 VAALINCGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGDNAEQVANMIEECGGIDKIE 612
+ A+I+ + P +L + + ++N +G EQ+ ++ G I +
Sbjct: 371 IQAVIDANIFPVLIEILQKAEFRTRKEAAWAITN--ATSGGTPEQIRYLV-SLGCIKPLC 427
Query: 613 DLQTHXKMEIYKMA 654
DL T +I ++A
Sbjct: 428 DLLTVMDSKIVQVA 441
Score = 64.9 bits (151), Expect = 2e-10
Identities = 54/189 (28%), Positives = 86/189 (45%), Gaps = 1/189 (0%)
Frame = +1
Query: 91 IPLLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLT-HPKEKICKEAVW 267
I LL+ VQ A+ A+GNI + VLNC L+ LLT + + + AVW
Sbjct: 173 IELLNSDFEDVQEQAVWALGNIAGDSSVCRDYVLNCSILNPLLTLLTKSTRLTMTRNAVW 232
Query: 268 FLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALI 447
LSN+ G + + LP++ L + +A WA+S LS G +++ A+I
Sbjct: 233 ALSNLCRGKNPPPEFAKVSPCLPVLSRLLFSSDSDLLADACWALSYLS-DGPNEKIQAVI 291
Query: 448 NCGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGDNAEQVANMIEECGGIDKIEDLQTH 627
+ GV LL D +V + L + N+ + GD+ + +I C + + L +
Sbjct: 292 DSGVCRRLVELLMHNDYKVASPALRAVGNI--VTGDDIQ--TQVILNCSALPCLLHLLSS 347
Query: 628 XKMEIYKMA 654
K I K A
Sbjct: 348 PKESIRKEA 356
Score = 58.0 bits (134), Expect = 3e-08
Identities = 36/100 (36%), Positives = 55/100 (55%), Gaps = 4/100 (4%)
Frame = +1
Query: 256 EAVWFLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLS--ISGTRD 429
EA W L+NI +G QQ + VI+AG +P+ + L+ Q++A WA+ N++ S RD
Sbjct: 144 EAAWALTNIASGTSQQTKIVIEAGAVPIFIELLNSDFEDVQEQAVWALGNIAGDSSVCRD 203
Query: 430 QVAALINCGVIPPFCNLL--SCKDTQVINVVLDGLSNMLK 543
V +NC ++ P LL S + T N V LSN+ +
Sbjct: 204 YV---LNCSILNPLLTLLTKSTRLTMTRNAVW-ALSNLCR 239
Score = 56.8 bits (131), Expect = 7e-08
Identities = 41/161 (25%), Positives = 73/161 (45%), Gaps = 1/161 (0%)
Frame = +1
Query: 85 PXIPLLSHKEVKVQTA-ALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEA 261
P + LL+ T A+ A+ N+ G + + L LL + +A
Sbjct: 213 PLLTLLTKSTRLTMTRNAVWALSNLCRGKNPPPEFAKVSPCLPVLSRLLFSSDSDLLADA 272
Query: 262 VWFLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAA 441
W LS ++ G +++QAVID+G+ +V L +++ A AV N+ ++G Q
Sbjct: 273 CWALSYLSDGPNEKIQAVIDSGVCRRLVELLMHNDYKVASPALRAVGNI-VTGDDIQTQV 331
Query: 442 LINCGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGDNAE 564
++NC +P +LLS + +SN+ AG+ A+
Sbjct: 332 ILNCSALPCLLHLLSSPKESIRKEACWTISNI--TAGNRAQ 370
Score = 55.2 bits (127), Expect = 2e-07
Identities = 33/105 (31%), Positives = 55/105 (52%), Gaps = 1/105 (0%)
Frame = +1
Query: 97 LLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWFLS 276
L ++ +Q A A+ NI +GT +QT++V+ A+ F LL E + ++AVW L
Sbjct: 133 LKRNENCTLQFEAAWALTNIASGTSQQTKIVIEAGAVPIFIELLNSDFEDVQEQAVWALG 192
Query: 277 NITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQ-KEAAWAVSNL 408
NI + V++ +L ++ L+K T + A WA+SNL
Sbjct: 193 NIAGDSSVCRDYVLNCSILNPLLTLLTKSTRLTMTRNAVWALSNL 237
Score = 37.9 bits (84), Expect = 0.032
Identities = 16/34 (47%), Positives = 23/34 (67%)
Frame = +3
Query: 3 DTVWAISYLTXGGNEQIQMVIXSGIVTTLXSVVV 104
D WA+SYL+ G NE+IQ VI SG+ L +++
Sbjct: 271 DACWALSYLSDGPNEKIQAVIDSGVCRRLVELLM 304
Score = 37.5 bits (83), Expect = 0.043
Identities = 23/62 (37%), Positives = 34/62 (54%)
Frame = +1
Query: 376 QKEAAWAVSNLSISGTRDQVAALINCGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGD 555
Q EAAWA++N++ SGT Q +I G +P F LL+ V + L N +AGD
Sbjct: 142 QFEAAWALTNIA-SGTSQQTKIVIEAGAVPIFIELLNSDFEDVQEQAVWALGN---IAGD 197
Query: 556 NA 561
++
Sbjct: 198 SS 199
>BC047409-1|AAH47409.1| 539|Homo sapiens karyopherin alpha 5
(importin alpha 6) protein.
Length = 539
Score = 200 bits (487), Expect = 5e-51
Identities = 98/199 (49%), Positives = 136/199 (68%), Gaps = 7/199 (3%)
Frame = +1
Query: 91 IPLLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWF 270
+ LL H + KV + ALRAVGNIVTG D QTQV+LNC AL LL+ PKE I KEA W
Sbjct: 303 VELLMHNDYKVVSPALRAVGNIVTGDDIQTQVILNCSALPCLLHLLSSPKESIRKEACWT 362
Query: 271 LSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALIN 450
+SNITAGN+ Q+QAVIDA + P+++ L K EF+T+KEAAWA++N + GT +Q+ L+
Sbjct: 363 VSNITAGNRAQIQAVIDANIFPVLIEILQKAEFRTRKEAAWAITNATSGGTPEQIRYLVA 422
Query: 451 CGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGDNAEQ-------VANMIEECGGIDKI 609
G I P C+LL+ D++++ V L+GL N+L++ ++Q +IEE G+DKI
Sbjct: 423 LGCIKPLCDLLTVMDSKIVQVALNGLENILRLGEQESKQNGIGINPYCALIEEAYGLDKI 482
Query: 610 EDLQTHXKMEIYKMAYDII 666
E LQ+H EIY+ A+D+I
Sbjct: 483 EFLQSHENQEIYQKAFDLI 501
Score = 64.9 bits (151), Expect = 2e-10
Identities = 43/171 (25%), Positives = 81/171 (47%)
Frame = +1
Query: 142 AVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWFLSNITAGNKQQVQAVID 321
A+ + G +++ Q V++ LL H K+ A+ + NI G+ Q Q +++
Sbjct: 278 ALSYLSDGPNDKIQAVIDSGVCRRLVELLMHNDYKVVSPALRAVGNIVTGDDIQTQVILN 337
Query: 322 AGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALINCGVIPPFCNLLSCKDTQ 501
LP ++ LS + +KEA W VSN++ +G R Q+ A+I+ + P +L + +
Sbjct: 338 CSALPCLLHLLSSPKESIRKEACWTVSNIT-AGNRAQIQAVIDANIFPVLIEILQKAEFR 396
Query: 502 VINVVLDGLSNMLKMAGDNAEQVANMIEECGGIDKIEDLQTHXKMEIYKMA 654
++N +G EQ+ ++ G I + DL T +I ++A
Sbjct: 397 TRKEAAWAITN--ATSGGTPEQIRYLV-ALGCIKPLCDLLTVMDSKIVQVA 444
Score = 64.5 bits (150), Expect = 3e-10
Identities = 54/189 (28%), Positives = 84/189 (44%), Gaps = 1/189 (0%)
Frame = +1
Query: 91 IPLLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKE-KICKEAVW 267
I LL+ + VQ A+ A+GNI E VLNC+ L LLT+ + AVW
Sbjct: 176 IKLLNSEHEDVQEQAVWALGNIAGDNAECRDFVLNCEILPPLLELLTNSNRLTTTRNAVW 235
Query: 268 FLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALI 447
LSN+ G + L ++ L + + WA+S LS G D++ A+I
Sbjct: 236 ALSNLCRGKNPPPNFSKVSPCLNVLSRLLFSSDPDVLADVCWALSYLS-DGPNDKIQAVI 294
Query: 448 NCGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGDNAEQVANMIEECGGIDKIEDLQTH 627
+ GV LL D +V++ L + N+ + GD+ + +I C + + L +
Sbjct: 295 DSGVCRRLVELLMHNDYKVVSPALRAVGNI--VTGDDIQ--TQVILNCSALPCLLHLLSS 350
Query: 628 XKMEIYKMA 654
K I K A
Sbjct: 351 PKESIRKEA 359
Score = 55.6 bits (128), Expect = 2e-07
Identities = 33/97 (34%), Positives = 51/97 (52%), Gaps = 1/97 (1%)
Frame = +1
Query: 121 VQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWFLSNITAGNKQ 300
+Q A A+ NI +GT T+VV+ A+ F LL E + ++AVW L NI N +
Sbjct: 144 LQFEAAWALTNIASGTFLHTKVVIETGAVPIFIKLLNSEHEDVQEQAVWALGNIAGDNAE 203
Query: 301 QVQAVIDAGLLPMIVANL-SKGEFQTQKEAAWAVSNL 408
V++ +LP ++ L + T + A WA+SNL
Sbjct: 204 CRDFVLNCEILPPLLELLTNSNRLTTTRNAVWALSNL 240
Score = 53.6 bits (123), Expect = 6e-07
Identities = 40/161 (24%), Positives = 72/161 (44%), Gaps = 1/161 (0%)
Frame = +1
Query: 85 PXIPLLSHKEVKVQTA-ALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEA 261
P + LL++ T A+ A+ N+ G + L+ LL + +
Sbjct: 216 PLLELLTNSNRLTTTRNAVWALSNLCRGKNPPPNFSKVSPCLNVLSRLLFSSDPDVLADV 275
Query: 262 VWFLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAA 441
W LS ++ G ++QAVID+G+ +V L +++ A AV N+ ++G Q
Sbjct: 276 CWALSYLSDGPNDKIQAVIDSGVCRRLVELLMHNDYKVVSPALRAVGNI-VTGDDIQTQV 334
Query: 442 LINCGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGDNAE 564
++NC +P +LLS + +SN+ AG+ A+
Sbjct: 335 ILNCSALPCLLHLLSSPKESIRKEACWTVSNI--TAGNRAQ 373
Score = 43.2 bits (97), Expect = 9e-04
Identities = 31/87 (35%), Positives = 45/87 (51%), Gaps = 1/87 (1%)
Frame = +1
Query: 307 QAVIDAGLLPMIVANLSKGEFQT-QKEAAWAVSNLSISGTRDQVAALINCGVIPPFCNLL 483
Q + G++ V L + E T Q EAAWA++N++ SGT +I G +P F LL
Sbjct: 121 QVIQKPGVVQRFVKFLERNENCTLQFEAAWALTNIA-SGTFLHTKVVIETGAVPIFIKLL 179
Query: 484 SCKDTQVINVVLDGLSNMLKMAGDNAE 564
+ + V + L N +AGDNAE
Sbjct: 180 NSEHEDVQEQAVWALGN---IAGDNAE 203
Score = 36.7 bits (81), Expect = 0.074
Identities = 15/34 (44%), Positives = 23/34 (67%)
Frame = +3
Query: 3 DTVWAISYLTXGGNEQIQMVIXSGIVTTLXSVVV 104
D WA+SYL+ G N++IQ VI SG+ L +++
Sbjct: 274 DVCWALSYLSDGPNDKIQAVIDSGVCRRLVELLM 307
>AL132795-5|CAI20500.1| 539|Homo sapiens karyopherin alpha 5
(importin alpha 6) protein.
Length = 539
Score = 200 bits (487), Expect = 5e-51
Identities = 98/199 (49%), Positives = 136/199 (68%), Gaps = 7/199 (3%)
Frame = +1
Query: 91 IPLLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWF 270
+ LL H + KV + ALRAVGNIVTG D QTQV+LNC AL LL+ PKE I KEA W
Sbjct: 303 VELLMHNDYKVVSPALRAVGNIVTGDDIQTQVILNCSALPCLLHLLSSPKESIRKEACWT 362
Query: 271 LSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALIN 450
+SNITAGN+ Q+QAVIDA + P+++ L K EF+T+KEAAWA++N + GT +Q+ L+
Sbjct: 363 VSNITAGNRAQIQAVIDANIFPVLIEILQKAEFRTRKEAAWAITNATSGGTPEQIRYLVA 422
Query: 451 CGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGDNAEQ-------VANMIEECGGIDKI 609
G I P C+LL+ D++++ V L+GL N+L++ ++Q +IEE G+DKI
Sbjct: 423 LGCIKPLCDLLTVMDSKIVQVALNGLENILRLGEQESKQNGIGINPYCALIEEAYGLDKI 482
Query: 610 EDLQTHXKMEIYKMAYDII 666
E LQ+H EIY+ A+D+I
Sbjct: 483 EFLQSHENQEIYQKAFDLI 501
Score = 64.9 bits (151), Expect = 2e-10
Identities = 43/171 (25%), Positives = 81/171 (47%)
Frame = +1
Query: 142 AVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWFLSNITAGNKQQVQAVID 321
A+ + G +++ Q V++ LL H K+ A+ + NI G+ Q Q +++
Sbjct: 278 ALSYLSDGPNDKIQAVIDSGVCRRLVELLMHNDYKVVSPALRAVGNIVTGDDIQTQVILN 337
Query: 322 AGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALINCGVIPPFCNLLSCKDTQ 501
LP ++ LS + +KEA W VSN++ +G R Q+ A+I+ + P +L + +
Sbjct: 338 CSALPCLLHLLSSPKESIRKEACWTVSNIT-AGNRAQIQAVIDANIFPVLIEILQKAEFR 396
Query: 502 VINVVLDGLSNMLKMAGDNAEQVANMIEECGGIDKIEDLQTHXKMEIYKMA 654
++N +G EQ+ ++ G I + DL T +I ++A
Sbjct: 397 TRKEAAWAITN--ATSGGTPEQIRYLV-ALGCIKPLCDLLTVMDSKIVQVA 444
Score = 64.5 bits (150), Expect = 3e-10
Identities = 54/189 (28%), Positives = 84/189 (44%), Gaps = 1/189 (0%)
Frame = +1
Query: 91 IPLLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKE-KICKEAVW 267
I LL+ + VQ A+ A+GNI E VLNC+ L LLT+ + AVW
Sbjct: 176 IKLLNSEHEDVQEQAVWALGNIAGDNAECRDFVLNCEILPPLLELLTNSNRLTTTRNAVW 235
Query: 268 FLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALI 447
LSN+ G + L ++ L + + WA+S LS G D++ A+I
Sbjct: 236 ALSNLCRGKNPPPNFSKVSPCLNVLSRLLFSSDPDVLADVCWALSYLS-DGPNDKIQAVI 294
Query: 448 NCGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGDNAEQVANMIEECGGIDKIEDLQTH 627
+ GV LL D +V++ L + N+ + GD+ + +I C + + L +
Sbjct: 295 DSGVCRRLVELLMHNDYKVVSPALRAVGNI--VTGDDIQ--TQVILNCSALPCLLHLLSS 350
Query: 628 XKMEIYKMA 654
K I K A
Sbjct: 351 PKESIRKEA 359
Score = 55.6 bits (128), Expect = 2e-07
Identities = 33/97 (34%), Positives = 51/97 (52%), Gaps = 1/97 (1%)
Frame = +1
Query: 121 VQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWFLSNITAGNKQ 300
+Q A A+ NI +GT T+VV+ A+ F LL E + ++AVW L NI N +
Sbjct: 144 LQFEAAWALTNIASGTFLHTKVVIETGAVPIFIKLLNSEHEDVQEQAVWALGNIAGDNAE 203
Query: 301 QVQAVIDAGLLPMIVANL-SKGEFQTQKEAAWAVSNL 408
V++ +LP ++ L + T + A WA+SNL
Sbjct: 204 CRDFVLNCEILPPLLELLTNSNRLTTTRNAVWALSNL 240
Score = 53.6 bits (123), Expect = 6e-07
Identities = 40/161 (24%), Positives = 72/161 (44%), Gaps = 1/161 (0%)
Frame = +1
Query: 85 PXIPLLSHKEVKVQTA-ALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEA 261
P + LL++ T A+ A+ N+ G + L+ LL + +
Sbjct: 216 PLLELLTNSNRLTTTRNAVWALSNLCRGKNPPPNFSKVSPCLNVLSRLLFSSDPDVLADV 275
Query: 262 VWFLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAA 441
W LS ++ G ++QAVID+G+ +V L +++ A AV N+ ++G Q
Sbjct: 276 CWALSYLSDGPNDKIQAVIDSGVCRRLVELLMHNDYKVVSPALRAVGNI-VTGDDIQTQV 334
Query: 442 LINCGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGDNAE 564
++NC +P +LLS + +SN+ AG+ A+
Sbjct: 335 ILNCSALPCLLHLLSSPKESIRKEACWTVSNI--TAGNRAQ 373
Score = 43.2 bits (97), Expect = 9e-04
Identities = 31/87 (35%), Positives = 45/87 (51%), Gaps = 1/87 (1%)
Frame = +1
Query: 307 QAVIDAGLLPMIVANLSKGEFQT-QKEAAWAVSNLSISGTRDQVAALINCGVIPPFCNLL 483
Q + G++ V L + E T Q EAAWA++N++ SGT +I G +P F LL
Sbjct: 121 QVIQKPGVVQRFVKFLERNENCTLQFEAAWALTNIA-SGTFLHTKVVIETGAVPIFIKLL 179
Query: 484 SCKDTQVINVVLDGLSNMLKMAGDNAE 564
+ + V + L N +AGDNAE
Sbjct: 180 NSEHEDVQEQAVWALGN---IAGDNAE 203
Score = 36.7 bits (81), Expect = 0.074
Identities = 15/34 (44%), Positives = 23/34 (67%)
Frame = +3
Query: 3 DTVWAISYLTXGGNEQIQMVIXSGIVTTLXSVVV 104
D WA+SYL+ G N++IQ VI SG+ L +++
Sbjct: 274 DVCWALSYLSDGPNDKIQAVIDSGVCRRLVELLM 307
>AF005361-1|AAC51868.1| 536|Homo sapiens importin alpha 6 protein.
Length = 536
Score = 200 bits (487), Expect = 5e-51
Identities = 98/199 (49%), Positives = 136/199 (68%), Gaps = 7/199 (3%)
Frame = +1
Query: 91 IPLLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWF 270
+ LL H + KV + ALRAVGNIVTG D QTQV+LNC AL LL+ PKE I KEA W
Sbjct: 300 VELLMHNDYKVVSPALRAVGNIVTGDDIQTQVILNCSALPCLLHLLSSPKESIRKEACWT 359
Query: 271 LSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALIN 450
+SNITAGN+ Q+QAVIDA + P+++ L K EF+T+KEAAWA++N + GT +Q+ L+
Sbjct: 360 VSNITAGNRAQIQAVIDANIFPVLIEILQKAEFRTRKEAAWAITNATSGGTPEQIRYLVA 419
Query: 451 CGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGDNAEQ-------VANMIEECGGIDKI 609
G I P C+LL+ D++++ V L+GL N+L++ ++Q +IEE G+DKI
Sbjct: 420 LGCIKPLCDLLTVMDSKIVQVALNGLENILRLGEQESKQNGIGINPYCALIEEAYGLDKI 479
Query: 610 EDLQTHXKMEIYKMAYDII 666
E LQ+H EIY+ A+D+I
Sbjct: 480 EFLQSHENQEIYQKAFDLI 498
Score = 64.9 bits (151), Expect = 2e-10
Identities = 43/171 (25%), Positives = 81/171 (47%)
Frame = +1
Query: 142 AVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWFLSNITAGNKQQVQAVID 321
A+ + G +++ Q V++ LL H K+ A+ + NI G+ Q Q +++
Sbjct: 275 ALSYLSDGPNDKIQAVIDSGVCRRLVELLMHNDYKVVSPALRAVGNIVTGDDIQTQVILN 334
Query: 322 AGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALINCGVIPPFCNLLSCKDTQ 501
LP ++ LS + +KEA W VSN++ +G R Q+ A+I+ + P +L + +
Sbjct: 335 CSALPCLLHLLSSPKESIRKEACWTVSNIT-AGNRAQIQAVIDANIFPVLIEILQKAEFR 393
Query: 502 VINVVLDGLSNMLKMAGDNAEQVANMIEECGGIDKIEDLQTHXKMEIYKMA 654
++N +G EQ+ ++ G I + DL T +I ++A
Sbjct: 394 TRKEAAWAITN--ATSGGTPEQIRYLV-ALGCIKPLCDLLTVMDSKIVQVA 441
Score = 64.5 bits (150), Expect = 3e-10
Identities = 54/189 (28%), Positives = 84/189 (44%), Gaps = 1/189 (0%)
Frame = +1
Query: 91 IPLLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKE-KICKEAVW 267
I LL+ + VQ A+ A+GNI E VLNC+ L LLT+ + AVW
Sbjct: 173 IKLLNSEHEDVQEQAVWALGNIAGDNAECRDFVLNCEILPPLLELLTNSNRLTTTRNAVW 232
Query: 268 FLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALI 447
LSN+ G + L ++ L + + WA+S LS G D++ A+I
Sbjct: 233 ALSNLCRGKNPPPNFSKVSPCLNVLSRLLFSSDPDVLADVCWALSYLS-DGPNDKIQAVI 291
Query: 448 NCGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGDNAEQVANMIEECGGIDKIEDLQTH 627
+ GV LL D +V++ L + N+ + GD+ + +I C + + L +
Sbjct: 292 DSGVCRRLVELLMHNDYKVVSPALRAVGNI--VTGDDIQ--TQVILNCSALPCLLHLLSS 347
Query: 628 XKMEIYKMA 654
K I K A
Sbjct: 348 PKESIRKEA 356
Score = 55.6 bits (128), Expect = 2e-07
Identities = 33/97 (34%), Positives = 51/97 (52%), Gaps = 1/97 (1%)
Frame = +1
Query: 121 VQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWFLSNITAGNKQ 300
+Q A A+ NI +GT T+VV+ A+ F LL E + ++AVW L NI N +
Sbjct: 141 LQFEAAWALTNIASGTFLHTKVVIETGAVPIFIKLLNSEHEDVQEQAVWALGNIAGDNAE 200
Query: 301 QVQAVIDAGLLPMIVANL-SKGEFQTQKEAAWAVSNL 408
V++ +LP ++ L + T + A WA+SNL
Sbjct: 201 CRDFVLNCEILPPLLELLTNSNRLTTTRNAVWALSNL 237
Score = 53.6 bits (123), Expect = 6e-07
Identities = 40/161 (24%), Positives = 72/161 (44%), Gaps = 1/161 (0%)
Frame = +1
Query: 85 PXIPLLSHKEVKVQTA-ALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEA 261
P + LL++ T A+ A+ N+ G + L+ LL + +
Sbjct: 213 PLLELLTNSNRLTTTRNAVWALSNLCRGKNPPPNFSKVSPCLNVLSRLLFSSDPDVLADV 272
Query: 262 VWFLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAA 441
W LS ++ G ++QAVID+G+ +V L +++ A AV N+ ++G Q
Sbjct: 273 CWALSYLSDGPNDKIQAVIDSGVCRRLVELLMHNDYKVVSPALRAVGNI-VTGDDIQTQV 331
Query: 442 LINCGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGDNAE 564
++NC +P +LLS + +SN+ AG+ A+
Sbjct: 332 ILNCSALPCLLHLLSSPKESIRKEACWTVSNI--TAGNRAQ 370
Score = 43.2 bits (97), Expect = 9e-04
Identities = 31/87 (35%), Positives = 45/87 (51%), Gaps = 1/87 (1%)
Frame = +1
Query: 307 QAVIDAGLLPMIVANLSKGEFQT-QKEAAWAVSNLSISGTRDQVAALINCGVIPPFCNLL 483
Q + G++ V L + E T Q EAAWA++N++ SGT +I G +P F LL
Sbjct: 118 QVIQKPGVVQRFVKFLERNENCTLQFEAAWALTNIA-SGTFLHTKVVIETGAVPIFIKLL 176
Query: 484 SCKDTQVINVVLDGLSNMLKMAGDNAE 564
+ + V + L N +AGDNAE
Sbjct: 177 NSEHEDVQEQAVWALGN---IAGDNAE 200
Score = 36.7 bits (81), Expect = 0.074
Identities = 15/34 (44%), Positives = 23/34 (67%)
Frame = +3
Query: 3 DTVWAISYLTXGGNEQIQMVIXSGIVTTLXSVVV 104
D WA+SYL+ G N++IQ VI SG+ L +++
Sbjct: 271 DVCWALSYLSDGPNDKIQAVIDSGVCRRLVELLM 304
>S75295-1|AAC60648.1| 538|Homo sapiens nucleoprotein interactor 1
protein.
Length = 538
Score = 196 bits (479), Expect = 4e-50
Identities = 95/199 (47%), Positives = 134/199 (67%), Gaps = 7/199 (3%)
Frame = +1
Query: 91 IPLLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWF 270
+ LL H + KV + ALRAVGNIVTG D QTQV+LNC AL LL+ PKE I KEA W
Sbjct: 302 VELLMHNDYKVVSPALRAVGNIVTGDDIQTQVILNCSALQSLLHLLSSPKESIKKEACWT 361
Query: 271 LSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALIN 450
+SNITAGN+ Q+Q VIDA + P +++ L EF+T+KEAAWA++N + G+ +Q+ L+
Sbjct: 362 ISNITAGNRAQIQTVIDANIFPALISILQTAEFRTRKEAAWAITNATSGGSAEQIKYLVE 421
Query: 451 CGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGDNAEQ-------VANMIEECGGIDKI 609
G I P C+LL+ D++++ V L+GL N+L++ A++ +IEE G+DKI
Sbjct: 422 LGCIKPLCDLLTVMDSKIVQVALNGLENILRLGEQEAKRNGTGINPYCALIEEAYGLDKI 481
Query: 610 EDLQTHXKMEIYKMAYDII 666
E LQ+H EIY+ A+D+I
Sbjct: 482 EFLQSHENQEIYQKAFDLI 500
Score = 68.1 bits (159), Expect = 3e-11
Identities = 46/186 (24%), Positives = 88/186 (47%)
Frame = +1
Query: 97 LLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWFLS 276
LL + V A A+ + G +++ Q V++ LL H K+ A+ +
Sbjct: 262 LLFVSDTDVLADACWALSYLSDGPNDKIQAVIDAGVCRRLVELLMHNDYKVVSPALRAVG 321
Query: 277 NITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALINCG 456
NI G+ Q Q +++ L ++ LS + +KEA W +SN++ +G R Q+ +I+
Sbjct: 322 NIVTGDDIQTQVILNCSALQSLLHLLSSPKESIKKEACWTISNIT-AGNRAQIQTVIDAN 380
Query: 457 VIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGDNAEQVANMIEECGGIDKIEDLQTHXKM 636
+ P ++L + + ++N +G +AEQ+ ++ E G I + DL T
Sbjct: 381 IFPALISILQTAEFRTRKEAAWAITN--ATSGGSAEQIKYLV-ELGCIKPLCDLLTVMDS 437
Query: 637 EIYKMA 654
+I ++A
Sbjct: 438 KIVQVA 443
Score = 55.6 bits (128), Expect = 2e-07
Identities = 34/100 (34%), Positives = 54/100 (54%), Gaps = 4/100 (4%)
Frame = +1
Query: 256 EAVWFLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGT--RD 429
E+ W L+NI +GN Q + VI A +P+ + LS Q++A WA+ N++ T RD
Sbjct: 146 ESAWVLTNIASGNSLQTRIVIQARAVPIFIELLSSEFEDVQEQAVWALGNIAGDSTMCRD 205
Query: 430 QVAALINCGVIPPFCNLLSCKD--TQVINVVLDGLSNMLK 543
V ++C ++PP L S ++ T N V LSN+ +
Sbjct: 206 YV---LDCNILPPLLQLFSKQNRLTMTRNAVW-ALSNLCR 241
Score = 54.4 bits (125), Expect = 3e-07
Identities = 34/108 (31%), Positives = 54/108 (50%), Gaps = 2/108 (1%)
Frame = +1
Query: 91 IPLLSHKE-VKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVW 267
+ L KE +Q + + NI +G QT++V+ A+ F LL+ E + ++AVW
Sbjct: 132 VEFLKRKENCSLQFESAWVLTNIASGNSLQTRIVIQARAVPIFIELLSSEFEDVQEQAVW 191
Query: 268 FLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQ-KEAAWAVSNL 408
L NI + V+D +LP ++ SK T + A WA+SNL
Sbjct: 192 ALGNIAGDSTMCRDYVLDCNILPPLLQLFSKQNRLTMTRNAVWALSNL 239
Score = 54.0 bits (124), Expect = 5e-07
Identities = 43/168 (25%), Positives = 75/168 (44%), Gaps = 1/168 (0%)
Frame = +1
Query: 85 PXIPLLSHKEVKVQTA-ALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEA 261
P + L S + T A+ A+ N+ G + L+ LL + +A
Sbjct: 215 PLLQLFSKQNRLTMTRNAVWALSNLCRGKSPPPEFAKVSPCLNVLSWLLFVSDTDVLADA 274
Query: 262 VWFLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAA 441
W LS ++ G ++QAVIDAG+ +V L +++ A AV N+ ++G Q
Sbjct: 275 CWALSYLSDGPNDKIQAVIDAGVCRRLVELLMHNDYKVVSPALRAVGNI-VTGDDIQTQV 333
Query: 442 LINCGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGDNAEQVANMIE 585
++NC + +LLS + +SN+ AG+ A Q+ +I+
Sbjct: 334 ILNCSALQSLLHLLSSPKESIKKEACWTISNI--TAGNRA-QIQTVID 378
Score = 43.6 bits (98), Expect = 6e-04
Identities = 31/135 (22%), Positives = 65/135 (48%), Gaps = 1/135 (0%)
Frame = +1
Query: 82 QPXIPLLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEA 261
Q + LLS + ++ A + NI G Q Q V++ + ++L + + KEA
Sbjct: 341 QSLLHLLSSPKESIKKEACWTISNITAGNRAQIQTVIDANIFPALISILQTAEFRTRKEA 400
Query: 262 VWFLSNITA-GNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVA 438
W ++N T+ G+ +Q++ +++ G + + L+ + + + A + N+ G ++
Sbjct: 401 AWAITNATSGGSAEQIKYLVELGCIKPLCDLLTVMDSKIVQVALNGLENILRLGEQE--- 457
Query: 439 ALINCGVIPPFCNLL 483
A N I P+C L+
Sbjct: 458 AKRNGTGINPYCALI 472
Score = 35.5 bits (78), Expect = 0.17
Identities = 14/34 (41%), Positives = 23/34 (67%)
Frame = +3
Query: 3 DTVWAISYLTXGGNEQIQMVIXSGIVTTLXSVVV 104
D WA+SYL+ G N++IQ VI +G+ L +++
Sbjct: 273 DACWALSYLSDGPNDKIQAVIDAGVCRRLVELLM 306
Score = 29.9 bits (64), Expect = 8.5
Identities = 13/33 (39%), Positives = 18/33 (54%)
Frame = +3
Query: 3 DTVWAISYLTXGGNEQIQMVIXSGIVTTLXSVV 101
+ W IS +T G QIQ VI + I L S++
Sbjct: 357 EACWTISNITAGNRAQIQTVIDANIFPALISIL 389
>CR456743-1|CAG33024.1| 538|Homo sapiens KPNA1 protein.
Length = 538
Score = 196 bits (479), Expect = 4e-50
Identities = 95/199 (47%), Positives = 134/199 (67%), Gaps = 7/199 (3%)
Frame = +1
Query: 91 IPLLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWF 270
+ LL H + KV + ALRAVGNIVTG D QTQV+LNC AL LL+ PKE I KEA W
Sbjct: 302 VELLMHNDYKVVSPALRAVGNIVTGDDIQTQVILNCSALQSLLHLLSSPKESIKKEACWT 361
Query: 271 LSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALIN 450
+SNITAGN+ Q+Q VIDA + P +++ L EF+T+KEAAWA++N + G+ +Q+ L+
Sbjct: 362 ISNITAGNRAQIQTVIDANIFPALISILQTAEFRTRKEAAWAITNATSGGSAEQIKYLVE 421
Query: 451 CGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGDNAEQ-------VANMIEECGGIDKI 609
G I P C+LL+ D++++ V L+GL N+L++ A++ +IEE G+DKI
Sbjct: 422 LGCIKPLCDLLTVMDSKIVQVALNGLENILRLGEQEAKRNGTGINPYCALIEEAYGLDKI 481
Query: 610 EDLQTHXKMEIYKMAYDII 666
E LQ+H EIY+ A+D+I
Sbjct: 482 EFLQSHENQEIYQKAFDLI 500
Score = 68.1 bits (159), Expect = 3e-11
Identities = 46/186 (24%), Positives = 88/186 (47%)
Frame = +1
Query: 97 LLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWFLS 276
LL + V A A+ + G +++ Q V++ LL H K+ A+ +
Sbjct: 262 LLFVSDTDVLADACWALSYLSDGPNDKIQAVIDAGVCRRLVELLMHNDYKVVSPALRAVG 321
Query: 277 NITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALINCG 456
NI G+ Q Q +++ L ++ LS + +KEA W +SN++ +G R Q+ +I+
Sbjct: 322 NIVTGDDIQTQVILNCSALQSLLHLLSSPKESIKKEACWTISNIT-AGNRAQIQTVIDAN 380
Query: 457 VIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGDNAEQVANMIEECGGIDKIEDLQTHXKM 636
+ P ++L + + ++N +G +AEQ+ ++ E G I + DL T
Sbjct: 381 IFPALISILQTAEFRTRKEAAWAITN--ATSGGSAEQIKYLV-ELGCIKPLCDLLTVMDS 437
Query: 637 EIYKMA 654
+I ++A
Sbjct: 438 KIVQVA 443
Score = 58.8 bits (136), Expect = 2e-08
Identities = 35/100 (35%), Positives = 55/100 (55%), Gaps = 4/100 (4%)
Frame = +1
Query: 256 EAVWFLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGT--RD 429
E+ W L+NI +GN Q + VI AG +P+ + LS Q++A WA+ N++ T RD
Sbjct: 146 ESAWVLTNIASGNSLQTRIVIQAGAVPIFIELLSSEFEDVQEQAVWALGNIAGDSTMCRD 205
Query: 430 QVAALINCGVIPPFCNLLSCKD--TQVINVVLDGLSNMLK 543
V ++C ++PP L S ++ T N V LSN+ +
Sbjct: 206 YV---LDCNILPPLLQLFSKQNRLTMTRNAVW-ALSNLCR 241
Score = 54.4 bits (125), Expect = 3e-07
Identities = 34/108 (31%), Positives = 54/108 (50%), Gaps = 2/108 (1%)
Frame = +1
Query: 91 IPLLSHKE-VKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVW 267
+ L KE +Q + + NI +G QT++V+ A+ F LL+ E + ++AVW
Sbjct: 132 VEFLKRKENCTLQFESAWVLTNIASGNSLQTRIVIQAGAVPIFIELLSSEFEDVQEQAVW 191
Query: 268 FLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQ-KEAAWAVSNL 408
L NI + V+D +LP ++ SK T + A WA+SNL
Sbjct: 192 ALGNIAGDSTMCRDYVLDCNILPPLLQLFSKQNRLTMTRNAVWALSNL 239
Score = 54.0 bits (124), Expect = 5e-07
Identities = 43/168 (25%), Positives = 75/168 (44%), Gaps = 1/168 (0%)
Frame = +1
Query: 85 PXIPLLSHKEVKVQTA-ALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEA 261
P + L S + T A+ A+ N+ G + L+ LL + +A
Sbjct: 215 PLLQLFSKQNRLTMTRNAVWALSNLCRGKSPPPEFAKVSPCLNVLSWLLFVSDTDVLADA 274
Query: 262 VWFLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAA 441
W LS ++ G ++QAVIDAG+ +V L +++ A AV N+ ++G Q
Sbjct: 275 CWALSYLSDGPNDKIQAVIDAGVCRRLVELLMHNDYKVVSPALRAVGNI-VTGDDIQTQV 333
Query: 442 LINCGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGDNAEQVANMIE 585
++NC + +LLS + +SN+ AG+ A Q+ +I+
Sbjct: 334 ILNCSALQSLLHLLSSPKESIKKEACWTISNI--TAGNRA-QIQTVID 378
Score = 43.6 bits (98), Expect = 6e-04
Identities = 31/135 (22%), Positives = 65/135 (48%), Gaps = 1/135 (0%)
Frame = +1
Query: 82 QPXIPLLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEA 261
Q + LLS + ++ A + NI G Q Q V++ + ++L + + KEA
Sbjct: 341 QSLLHLLSSPKESIKKEACWTISNITAGNRAQIQTVIDANIFPALISILQTAEFRTRKEA 400
Query: 262 VWFLSNITA-GNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVA 438
W ++N T+ G+ +Q++ +++ G + + L+ + + + A + N+ G ++
Sbjct: 401 AWAITNATSGGSAEQIKYLVELGCIKPLCDLLTVMDSKIVQVALNGLENILRLGEQE--- 457
Query: 439 ALINCGVIPPFCNLL 483
A N I P+C L+
Sbjct: 458 AKRNGTGINPYCALI 472
Score = 35.5 bits (78), Expect = 0.17
Identities = 14/34 (41%), Positives = 23/34 (67%)
Frame = +3
Query: 3 DTVWAISYLTXGGNEQIQMVIXSGIVTTLXSVVV 104
D WA+SYL+ G N++IQ VI +G+ L +++
Sbjct: 273 DACWALSYLSDGPNDKIQAVIDAGVCRRLVELLM 306
Score = 29.9 bits (64), Expect = 8.5
Identities = 13/33 (39%), Positives = 18/33 (54%)
Frame = +3
Query: 3 DTVWAISYLTXGGNEQIQMVIXSGIVTTLXSVV 101
+ W IS +T G QIQ VI + I L S++
Sbjct: 357 EACWTISNITAGNRAQIQTVIDANIFPALISIL 389
>BT006959-1|AAP35605.1| 538|Homo sapiens karyopherin alpha 1
(importin alpha 5) protein.
Length = 538
Score = 196 bits (479), Expect = 4e-50
Identities = 95/199 (47%), Positives = 134/199 (67%), Gaps = 7/199 (3%)
Frame = +1
Query: 91 IPLLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWF 270
+ LL H + KV + ALRAVGNIVTG D QTQV+LNC AL LL+ PKE I KEA W
Sbjct: 302 VELLMHNDYKVVSPALRAVGNIVTGDDIQTQVILNCSALQSLLHLLSSPKESIKKEACWT 361
Query: 271 LSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALIN 450
+SNITAGN+ Q+Q VIDA + P +++ L EF+T+KEAAWA++N + G+ +Q+ L+
Sbjct: 362 ISNITAGNRAQIQTVIDANIFPALISILQTAEFRTRKEAAWAITNATSGGSAEQIKYLVE 421
Query: 451 CGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGDNAEQ-------VANMIEECGGIDKI 609
G I P C+LL+ D++++ V L+GL N+L++ A++ +IEE G+DKI
Sbjct: 422 LGCIKPLCDLLTVMDSKIVQVALNGLENILRLGEQEAKRNGTGINPYCALIEEAYGLDKI 481
Query: 610 EDLQTHXKMEIYKMAYDII 666
E LQ+H EIY+ A+D+I
Sbjct: 482 EFLQSHENQEIYQKAFDLI 500
Score = 68.1 bits (159), Expect = 3e-11
Identities = 46/186 (24%), Positives = 88/186 (47%)
Frame = +1
Query: 97 LLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWFLS 276
LL + V A A+ + G +++ Q V++ LL H K+ A+ +
Sbjct: 262 LLFVSDTDVLADACWALSYLSDGPNDKIQAVIDAGVCRRLVELLMHNDYKVVSPALRAVG 321
Query: 277 NITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALINCG 456
NI G+ Q Q +++ L ++ LS + +KEA W +SN++ +G R Q+ +I+
Sbjct: 322 NIVTGDDIQTQVILNCSALQSLLHLLSSPKESIKKEACWTISNIT-AGNRAQIQTVIDAN 380
Query: 457 VIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGDNAEQVANMIEECGGIDKIEDLQTHXKM 636
+ P ++L + + ++N +G +AEQ+ ++ E G I + DL T
Sbjct: 381 IFPALISILQTAEFRTRKEAAWAITN--ATSGGSAEQIKYLV-ELGCIKPLCDLLTVMDS 437
Query: 637 EIYKMA 654
+I ++A
Sbjct: 438 KIVQVA 443
Score = 58.8 bits (136), Expect = 2e-08
Identities = 35/100 (35%), Positives = 55/100 (55%), Gaps = 4/100 (4%)
Frame = +1
Query: 256 EAVWFLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGT--RD 429
E+ W L+NI +GN Q + VI AG +P+ + LS Q++A WA+ N++ T RD
Sbjct: 146 ESAWVLTNIASGNSLQTRIVIQAGAVPIFIELLSSEFEDVQEQAVWALGNIAGDSTMCRD 205
Query: 430 QVAALINCGVIPPFCNLLSCKD--TQVINVVLDGLSNMLK 543
V ++C ++PP L S ++ T N V LSN+ +
Sbjct: 206 YV---LDCNILPPLLQLFSKQNRLTMTRNAVW-ALSNLCR 241
Score = 54.4 bits (125), Expect = 3e-07
Identities = 34/108 (31%), Positives = 54/108 (50%), Gaps = 2/108 (1%)
Frame = +1
Query: 91 IPLLSHKE-VKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVW 267
+ L KE +Q + + NI +G QT++V+ A+ F LL+ E + ++AVW
Sbjct: 132 VEFLKRKENCTLQFESAWVLTNIASGNSLQTRIVIQAGAVPIFIELLSSEFEDVQEQAVW 191
Query: 268 FLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQ-KEAAWAVSNL 408
L NI + V+D +LP ++ SK T + A WA+SNL
Sbjct: 192 ALGNIAGDSTMCRDYVLDCNILPPLLQLFSKQNRLTMTRNAVWALSNL 239
Score = 54.0 bits (124), Expect = 5e-07
Identities = 43/168 (25%), Positives = 75/168 (44%), Gaps = 1/168 (0%)
Frame = +1
Query: 85 PXIPLLSHKEVKVQTA-ALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEA 261
P + L S + T A+ A+ N+ G + L+ LL + +A
Sbjct: 215 PLLQLFSKQNRLTMTRNAVWALSNLCRGKSPPPEFAKVSPCLNVLSWLLFVSDTDVLADA 274
Query: 262 VWFLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAA 441
W LS ++ G ++QAVIDAG+ +V L +++ A AV N+ ++G Q
Sbjct: 275 CWALSYLSDGPNDKIQAVIDAGVCRRLVELLMHNDYKVVSPALRAVGNI-VTGDDIQTQV 333
Query: 442 LINCGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGDNAEQVANMIE 585
++NC + +LLS + +SN+ AG+ A Q+ +I+
Sbjct: 334 ILNCSALQSLLHLLSSPKESIKKEACWTISNI--TAGNRA-QIQTVID 378
Score = 43.6 bits (98), Expect = 6e-04
Identities = 31/135 (22%), Positives = 65/135 (48%), Gaps = 1/135 (0%)
Frame = +1
Query: 82 QPXIPLLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEA 261
Q + LLS + ++ A + NI G Q Q V++ + ++L + + KEA
Sbjct: 341 QSLLHLLSSPKESIKKEACWTISNITAGNRAQIQTVIDANIFPALISILQTAEFRTRKEA 400
Query: 262 VWFLSNITA-GNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVA 438
W ++N T+ G+ +Q++ +++ G + + L+ + + + A + N+ G ++
Sbjct: 401 AWAITNATSGGSAEQIKYLVELGCIKPLCDLLTVMDSKIVQVALNGLENILRLGEQE--- 457
Query: 439 ALINCGVIPPFCNLL 483
A N I P+C L+
Sbjct: 458 AKRNGTGINPYCALI 472
Score = 35.5 bits (78), Expect = 0.17
Identities = 14/34 (41%), Positives = 23/34 (67%)
Frame = +3
Query: 3 DTVWAISYLTXGGNEQIQMVIXSGIVTTLXSVVV 104
D WA+SYL+ G N++IQ VI +G+ L +++
Sbjct: 273 DACWALSYLSDGPNDKIQAVIDAGVCRRLVELLM 306
Score = 29.9 bits (64), Expect = 8.5
Identities = 13/33 (39%), Positives = 18/33 (54%)
Frame = +3
Query: 3 DTVWAISYLTXGGNEQIQMVIXSGIVTTLXSVV 101
+ W IS +T G QIQ VI + I L S++
Sbjct: 357 EACWTISNITAGNRAQIQTVIDANIFPALISIL 389
>BC090864-1|AAH90864.1| 538|Homo sapiens karyopherin alpha 1
(importin alpha 5) protein.
Length = 538
Score = 196 bits (479), Expect = 4e-50
Identities = 95/199 (47%), Positives = 134/199 (67%), Gaps = 7/199 (3%)
Frame = +1
Query: 91 IPLLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWF 270
+ LL H + KV + ALRAVGNIVTG D QTQV+LNC AL LL+ PKE I KEA W
Sbjct: 302 VELLMHNDYKVVSPALRAVGNIVTGDDIQTQVILNCSALQSLLHLLSSPKESIKKEACWT 361
Query: 271 LSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALIN 450
+SNITAGN+ Q+Q VIDA + P +++ L EF+T+KEAAWA++N + G+ +Q+ L+
Sbjct: 362 ISNITAGNRAQIQTVIDANIFPALISILQTAEFRTRKEAAWAITNATSGGSAEQIKYLVE 421
Query: 451 CGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGDNAEQ-------VANMIEECGGIDKI 609
G I P C+LL+ D++++ V L+GL N+L++ A++ +IEE G+DKI
Sbjct: 422 LGCIKPLCDLLTVMDSKIVQVALNGLENILRLGEQEAKRNGTGINPYCALIEEAYGLDKI 481
Query: 610 EDLQTHXKMEIYKMAYDII 666
E LQ+H EIY+ A+D+I
Sbjct: 482 EFLQSHENQEIYQKAFDLI 500
Score = 68.1 bits (159), Expect = 3e-11
Identities = 46/186 (24%), Positives = 88/186 (47%)
Frame = +1
Query: 97 LLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWFLS 276
LL + V A A+ + G +++ Q V++ LL H K+ A+ +
Sbjct: 262 LLFVSDTDVLADACWALSYLSDGPNDKIQAVIDAGVCRRLVELLMHNDYKVVSPALRAVG 321
Query: 277 NITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALINCG 456
NI G+ Q Q +++ L ++ LS + +KEA W +SN++ +G R Q+ +I+
Sbjct: 322 NIVTGDDIQTQVILNCSALQSLLHLLSSPKESIKKEACWTISNIT-AGNRAQIQTVIDAN 380
Query: 457 VIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGDNAEQVANMIEECGGIDKIEDLQTHXKM 636
+ P ++L + + ++N +G +AEQ+ ++ E G I + DL T
Sbjct: 381 IFPALISILQTAEFRTRKEAAWAITN--ATSGGSAEQIKYLV-ELGCIKPLCDLLTVMDS 437
Query: 637 EIYKMA 654
+I ++A
Sbjct: 438 KIVQVA 443
Score = 58.8 bits (136), Expect = 2e-08
Identities = 35/100 (35%), Positives = 55/100 (55%), Gaps = 4/100 (4%)
Frame = +1
Query: 256 EAVWFLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGT--RD 429
E+ W L+NI +GN Q + VI AG +P+ + LS Q++A WA+ N++ T RD
Sbjct: 146 ESAWVLTNIASGNSLQTRIVIQAGAVPIFIELLSSEFEDVQEQAVWALGNIAGDSTMYRD 205
Query: 430 QVAALINCGVIPPFCNLLSCKD--TQVINVVLDGLSNMLK 543
V ++C ++PP L S ++ T N V LSN+ +
Sbjct: 206 YV---LDCNILPPLLQLFSKQNRLTMTRNAVW-ALSNLCR 241
Score = 55.2 bits (127), Expect = 2e-07
Identities = 34/108 (31%), Positives = 54/108 (50%), Gaps = 2/108 (1%)
Frame = +1
Query: 91 IPLLSHKE-VKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVW 267
+ L KE +Q + + NI +G QT++V+ A+ F LL+ E + ++AVW
Sbjct: 132 VEFLKRKENCTLQFESAWVLTNIASGNSLQTRIVIQAGAVPIFIELLSSEFEDVQEQAVW 191
Query: 268 FLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQ-KEAAWAVSNL 408
L NI + V+D +LP ++ SK T + A WA+SNL
Sbjct: 192 ALGNIAGDSTMYRDYVLDCNILPPLLQLFSKQNRLTMTRNAVWALSNL 239
Score = 54.0 bits (124), Expect = 5e-07
Identities = 43/168 (25%), Positives = 75/168 (44%), Gaps = 1/168 (0%)
Frame = +1
Query: 85 PXIPLLSHKEVKVQTA-ALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEA 261
P + L S + T A+ A+ N+ G + L+ LL + +A
Sbjct: 215 PLLQLFSKQNRLTMTRNAVWALSNLCRGKSPPPEFAKVSPCLNVLSWLLFVSDTDVLADA 274
Query: 262 VWFLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAA 441
W LS ++ G ++QAVIDAG+ +V L +++ A AV N+ ++G Q
Sbjct: 275 CWALSYLSDGPNDKIQAVIDAGVCRRLVELLMHNDYKVVSPALRAVGNI-VTGDDIQTQV 333
Query: 442 LINCGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGDNAEQVANMIE 585
++NC + +LLS + +SN+ AG+ A Q+ +I+
Sbjct: 334 ILNCSALQSLLHLLSSPKESIKKEACWTISNI--TAGNRA-QIQTVID 378
Score = 43.6 bits (98), Expect = 6e-04
Identities = 31/135 (22%), Positives = 65/135 (48%), Gaps = 1/135 (0%)
Frame = +1
Query: 82 QPXIPLLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEA 261
Q + LLS + ++ A + NI G Q Q V++ + ++L + + KEA
Sbjct: 341 QSLLHLLSSPKESIKKEACWTISNITAGNRAQIQTVIDANIFPALISILQTAEFRTRKEA 400
Query: 262 VWFLSNITA-GNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVA 438
W ++N T+ G+ +Q++ +++ G + + L+ + + + A + N+ G ++
Sbjct: 401 AWAITNATSGGSAEQIKYLVELGCIKPLCDLLTVMDSKIVQVALNGLENILRLGEQE--- 457
Query: 439 ALINCGVIPPFCNLL 483
A N I P+C L+
Sbjct: 458 AKRNGTGINPYCALI 472
Score = 35.5 bits (78), Expect = 0.17
Identities = 14/34 (41%), Positives = 23/34 (67%)
Frame = +3
Query: 3 DTVWAISYLTXGGNEQIQMVIXSGIVTTLXSVVV 104
D WA+SYL+ G N++IQ VI +G+ L +++
Sbjct: 273 DACWALSYLSDGPNDKIQAVIDAGVCRRLVELLM 306
Score = 29.9 bits (64), Expect = 8.5
Identities = 13/33 (39%), Positives = 18/33 (54%)
Frame = +3
Query: 3 DTVWAISYLTXGGNEQIQMVIXSGIVTTLXSVV 101
+ W IS +T G QIQ VI + I L S++
Sbjct: 357 EACWTISNITAGNRAQIQTVIDANIFPALISIL 389
>BC003009-1|AAH03009.1| 538|Homo sapiens karyopherin alpha 1
(importin alpha 5) protein.
Length = 538
Score = 196 bits (479), Expect = 4e-50
Identities = 95/199 (47%), Positives = 134/199 (67%), Gaps = 7/199 (3%)
Frame = +1
Query: 91 IPLLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWF 270
+ LL H + KV + ALRAVGNIVTG D QTQV+LNC AL LL+ PKE I KEA W
Sbjct: 302 VELLMHNDYKVVSPALRAVGNIVTGDDIQTQVILNCSALQSLLHLLSSPKESIKKEACWT 361
Query: 271 LSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALIN 450
+SNITAGN+ Q+Q VIDA + P +++ L EF+T+KEAAWA++N + G+ +Q+ L+
Sbjct: 362 ISNITAGNRAQIQTVIDANIFPALISILQTAEFRTRKEAAWAITNATSGGSAEQIKYLVE 421
Query: 451 CGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGDNAEQ-------VANMIEECGGIDKI 609
G I P C+LL+ D++++ V L+GL N+L++ A++ +IEE G+DKI
Sbjct: 422 LGCIKPLCDLLTVMDSKIVQVALNGLENILRLGEQEAKRNGTGINPYCALIEEAYGLDKI 481
Query: 610 EDLQTHXKMEIYKMAYDII 666
E LQ+H EIY+ A+D+I
Sbjct: 482 EFLQSHENQEIYQKAFDLI 500
Score = 68.1 bits (159), Expect = 3e-11
Identities = 46/186 (24%), Positives = 88/186 (47%)
Frame = +1
Query: 97 LLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWFLS 276
LL + V A A+ + G +++ Q V++ LL H K+ A+ +
Sbjct: 262 LLFVSDTDVLADACWALSYLSDGPNDKIQAVIDAGVCRRLVELLMHNDYKVVSPALRAVG 321
Query: 277 NITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALINCG 456
NI G+ Q Q +++ L ++ LS + +KEA W +SN++ +G R Q+ +I+
Sbjct: 322 NIVTGDDIQTQVILNCSALQSLLHLLSSPKESIKKEACWTISNIT-AGNRAQIQTVIDAN 380
Query: 457 VIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGDNAEQVANMIEECGGIDKIEDLQTHXKM 636
+ P ++L + + ++N +G +AEQ+ ++ E G I + DL T
Sbjct: 381 IFPALISILQTAEFRTRKEAAWAITN--ATSGGSAEQIKYLV-ELGCIKPLCDLLTVMDS 437
Query: 637 EIYKMA 654
+I ++A
Sbjct: 438 KIVQVA 443
Score = 58.8 bits (136), Expect = 2e-08
Identities = 35/100 (35%), Positives = 55/100 (55%), Gaps = 4/100 (4%)
Frame = +1
Query: 256 EAVWFLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGT--RD 429
E+ W L+NI +GN Q + VI AG +P+ + LS Q++A WA+ N++ T RD
Sbjct: 146 ESAWVLTNIASGNSLQTRIVIQAGAVPIFIELLSSEFEDVQEQAVWALGNIAGDSTMCRD 205
Query: 430 QVAALINCGVIPPFCNLLSCKD--TQVINVVLDGLSNMLK 543
V ++C ++PP L S ++ T N V LSN+ +
Sbjct: 206 YV---LDCNILPPLLQLFSKQNRLTMTRNAVW-ALSNLCR 241
Score = 54.4 bits (125), Expect = 3e-07
Identities = 34/108 (31%), Positives = 54/108 (50%), Gaps = 2/108 (1%)
Frame = +1
Query: 91 IPLLSHKE-VKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVW 267
+ L KE +Q + + NI +G QT++V+ A+ F LL+ E + ++AVW
Sbjct: 132 VEFLKRKENCTLQFESAWVLTNIASGNSLQTRIVIQAGAVPIFIELLSSEFEDVQEQAVW 191
Query: 268 FLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQ-KEAAWAVSNL 408
L NI + V+D +LP ++ SK T + A WA+SNL
Sbjct: 192 ALGNIAGDSTMCRDYVLDCNILPPLLQLFSKQNRLTMTRNAVWALSNL 239
Score = 54.0 bits (124), Expect = 5e-07
Identities = 43/168 (25%), Positives = 75/168 (44%), Gaps = 1/168 (0%)
Frame = +1
Query: 85 PXIPLLSHKEVKVQTA-ALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEA 261
P + L S + T A+ A+ N+ G + L+ LL + +A
Sbjct: 215 PLLQLFSKQNRLTMTRNAVWALSNLCRGKSPPPEFAKVSPCLNVLSWLLFVSDTDVLADA 274
Query: 262 VWFLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAA 441
W LS ++ G ++QAVIDAG+ +V L +++ A AV N+ ++G Q
Sbjct: 275 CWALSYLSDGPNDKIQAVIDAGVCRRLVELLMHNDYKVVSPALRAVGNI-VTGDDIQTQV 333
Query: 442 LINCGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGDNAEQVANMIE 585
++NC + +LLS + +SN+ AG+ A Q+ +I+
Sbjct: 334 ILNCSALQSLLHLLSSPKESIKKEACWTISNI--TAGNRA-QIQTVID 378
Score = 43.6 bits (98), Expect = 6e-04
Identities = 31/135 (22%), Positives = 65/135 (48%), Gaps = 1/135 (0%)
Frame = +1
Query: 82 QPXIPLLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEA 261
Q + LLS + ++ A + NI G Q Q V++ + ++L + + KEA
Sbjct: 341 QSLLHLLSSPKESIKKEACWTISNITAGNRAQIQTVIDANIFPALISILQTAEFRTRKEA 400
Query: 262 VWFLSNITA-GNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVA 438
W ++N T+ G+ +Q++ +++ G + + L+ + + + A + N+ G ++
Sbjct: 401 AWAITNATSGGSAEQIKYLVELGCIKPLCDLLTVMDSKIVQVALNGLENILRLGEQE--- 457
Query: 439 ALINCGVIPPFCNLL 483
A N I P+C L+
Sbjct: 458 AKRNGTGINPYCALI 472
Score = 35.5 bits (78), Expect = 0.17
Identities = 14/34 (41%), Positives = 23/34 (67%)
Frame = +3
Query: 3 DTVWAISYLTXGGNEQIQMVIXSGIVTTLXSVVV 104
D WA+SYL+ G N++IQ VI +G+ L +++
Sbjct: 273 DACWALSYLSDGPNDKIQAVIDAGVCRRLVELLM 306
Score = 29.9 bits (64), Expect = 8.5
Identities = 13/33 (39%), Positives = 18/33 (54%)
Frame = +3
Query: 3 DTVWAISYLTXGGNEQIQMVIXSGIVTTLXSVV 101
+ W IS +T G QIQ VI + I L S++
Sbjct: 357 EACWTISNITAGNRAQIQTVIDANIFPALISIL 389
>BC002374-1|AAH02374.1| 538|Homo sapiens karyopherin alpha 1
(importin alpha 5) protein.
Length = 538
Score = 196 bits (479), Expect = 4e-50
Identities = 95/199 (47%), Positives = 134/199 (67%), Gaps = 7/199 (3%)
Frame = +1
Query: 91 IPLLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWF 270
+ LL H + KV + ALRAVGNIVTG D QTQV+LNC AL LL+ PKE I KEA W
Sbjct: 302 VELLMHNDYKVVSPALRAVGNIVTGDDIQTQVILNCSALQSLLHLLSSPKESIKKEACWT 361
Query: 271 LSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALIN 450
+SNITAGN+ Q+Q VIDA + P +++ L EF+T+KEAAWA++N + G+ +Q+ L+
Sbjct: 362 ISNITAGNRAQIQTVIDANIFPALISILQTAEFRTRKEAAWAITNATSGGSAEQIKYLVE 421
Query: 451 CGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGDNAEQ-------VANMIEECGGIDKI 609
G I P C+LL+ D++++ V L+GL N+L++ A++ +IEE G+DKI
Sbjct: 422 LGCIKPLCDLLTVMDSKIVQVALNGLENILRLGEQEAKRNGTGINPYCALIEEAYGLDKI 481
Query: 610 EDLQTHXKMEIYKMAYDII 666
E LQ+H EIY+ A+D+I
Sbjct: 482 EFLQSHENQEIYQKAFDLI 500
Score = 68.1 bits (159), Expect = 3e-11
Identities = 46/186 (24%), Positives = 88/186 (47%)
Frame = +1
Query: 97 LLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWFLS 276
LL + V A A+ + G +++ Q V++ LL H K+ A+ +
Sbjct: 262 LLFVSDTDVLADACWALSYLSDGPNDKIQAVIDAGVCRRLVELLMHNDYKVVSPALRAVG 321
Query: 277 NITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALINCG 456
NI G+ Q Q +++ L ++ LS + +KEA W +SN++ +G R Q+ +I+
Sbjct: 322 NIVTGDDIQTQVILNCSALQSLLHLLSSPKESIKKEACWTISNIT-AGNRAQIQTVIDAN 380
Query: 457 VIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGDNAEQVANMIEECGGIDKIEDLQTHXKM 636
+ P ++L + + ++N +G +AEQ+ ++ E G I + DL T
Sbjct: 381 IFPALISILQTAEFRTRKEAAWAITN--ATSGGSAEQIKYLV-ELGCIKPLCDLLTVMDS 437
Query: 637 EIYKMA 654
+I ++A
Sbjct: 438 KIVQVA 443
Score = 58.8 bits (136), Expect = 2e-08
Identities = 35/100 (35%), Positives = 55/100 (55%), Gaps = 4/100 (4%)
Frame = +1
Query: 256 EAVWFLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGT--RD 429
E+ W L+NI +GN Q + VI AG +P+ + LS Q++A WA+ N++ T RD
Sbjct: 146 ESAWVLTNIASGNSLQTRIVIQAGAVPIFIELLSSEFEDVQEQAVWALGNIAGDSTMCRD 205
Query: 430 QVAALINCGVIPPFCNLLSCKD--TQVINVVLDGLSNMLK 543
V ++C ++PP L S ++ T N V LSN+ +
Sbjct: 206 YV---LDCNILPPLLQLFSKQNRLTMTRNAVW-ALSNLCR 241
Score = 54.4 bits (125), Expect = 3e-07
Identities = 34/108 (31%), Positives = 54/108 (50%), Gaps = 2/108 (1%)
Frame = +1
Query: 91 IPLLSHKE-VKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVW 267
+ L KE +Q + + NI +G QT++V+ A+ F LL+ E + ++AVW
Sbjct: 132 VEFLKRKENCTLQFESAWVLTNIASGNSLQTRIVIQAGAVPIFIELLSSEFEDVQEQAVW 191
Query: 268 FLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQ-KEAAWAVSNL 408
L NI + V+D +LP ++ SK T + A WA+SNL
Sbjct: 192 ALGNIAGDSTMCRDYVLDCNILPPLLQLFSKQNRLTMTRNAVWALSNL 239
Score = 54.0 bits (124), Expect = 5e-07
Identities = 43/168 (25%), Positives = 75/168 (44%), Gaps = 1/168 (0%)
Frame = +1
Query: 85 PXIPLLSHKEVKVQTA-ALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEA 261
P + L S + T A+ A+ N+ G + L+ LL + +A
Sbjct: 215 PLLQLFSKQNRLTMTRNAVWALSNLCRGKSPPPEFAKVSPCLNVLSWLLFVSDTDVLADA 274
Query: 262 VWFLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAA 441
W LS ++ G ++QAVIDAG+ +V L +++ A AV N+ ++G Q
Sbjct: 275 CWALSYLSDGPNDKIQAVIDAGVCRRLVELLMHNDYKVVSPALRAVGNI-VTGDDIQTQV 333
Query: 442 LINCGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGDNAEQVANMIE 585
++NC + +LLS + +SN+ AG+ A Q+ +I+
Sbjct: 334 ILNCSALQSLLHLLSSPKESIKKEACWTISNI--TAGNRA-QIQTVID 378
Score = 43.6 bits (98), Expect = 6e-04
Identities = 31/135 (22%), Positives = 65/135 (48%), Gaps = 1/135 (0%)
Frame = +1
Query: 82 QPXIPLLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEA 261
Q + LLS + ++ A + NI G Q Q V++ + ++L + + KEA
Sbjct: 341 QSLLHLLSSPKESIKKEACWTISNITAGNRAQIQTVIDANIFPALISILQTAEFRTRKEA 400
Query: 262 VWFLSNITA-GNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVA 438
W ++N T+ G+ +Q++ +++ G + + L+ + + + A + N+ G ++
Sbjct: 401 AWAITNATSGGSAEQIKYLVELGCIKPLCDLLTVMDSKIVQVALNGLENILRLGEQE--- 457
Query: 439 ALINCGVIPPFCNLL 483
A N I P+C L+
Sbjct: 458 AKRNGTGINPYCALI 472
Score = 35.5 bits (78), Expect = 0.17
Identities = 14/34 (41%), Positives = 23/34 (67%)
Frame = +3
Query: 3 DTVWAISYLTXGGNEQIQMVIXSGIVTTLXSVVV 104
D WA+SYL+ G N++IQ VI +G+ L +++
Sbjct: 273 DACWALSYLSDGPNDKIQAVIDAGVCRRLVELLM 306
Score = 29.9 bits (64), Expect = 8.5
Identities = 13/33 (39%), Positives = 18/33 (54%)
Frame = +3
Query: 3 DTVWAISYLTXGGNEQIQMVIXSGIVTTLXSVV 101
+ W IS +T G QIQ VI + I L S++
Sbjct: 357 EACWTISNITAGNRAQIQTVIDANIFPALISIL 389
>AL049795-1|CAI22054.1| 321|Homo sapiens karyopherin alpha 6
(importin alpha 7) protein.
Length = 321
Score = 140 bits (339), Expect = 4e-33
Identities = 66/115 (57%), Positives = 85/115 (73%)
Frame = +1
Query: 91 IPLLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWF 270
+ LL H + KV + ALRAVGNIVTG D QTQV+LNC AL LL+ PKE I KEA W
Sbjct: 207 VELLMHNDYKVASPALRAVGNIVTGDDIQTQVILNCSALPCLLHLLSSPKESIRKEACWT 266
Query: 271 LSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQV 435
+SNITAGN+ Q+QAVIDA + P+++ L K EF+T+KEAAWA++N + GT +Q+
Sbjct: 267 ISNITAGNRAQIQAVIDANIFPVLIEILQKAEFRTRKEAAWAITNATSGGTPEQI 321
Score = 63.7 bits (148), Expect = 6e-10
Identities = 37/137 (27%), Positives = 67/137 (48%), Gaps = 4/137 (2%)
Frame = +1
Query: 85 PXIPLLSH----KEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKIC 252
P +P+LS + + A A+ + G +E+ Q V++ LL H K+
Sbjct: 159 PCLPVLSRLLFSSDSDLLADACWALSYLSDGPNEKIQAVIDSGVCRRLVELLMHNDYKVA 218
Query: 253 KEAVWFLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQ 432
A+ + NI G+ Q Q +++ LP ++ LS + +KEA W +SN++ +G R Q
Sbjct: 219 SPALRAVGNIVTGDDIQTQVILNCSALPCLLHLLSSPKESIRKEACWTISNIT-AGNRAQ 277
Query: 433 VAALINCGVIPPFCNLL 483
+ A+I+ + P +L
Sbjct: 278 IQAVIDANIFPVLIEIL 294
Score = 60.5 bits (140), Expect = 5e-09
Identities = 49/175 (28%), Positives = 80/175 (45%), Gaps = 1/175 (0%)
Frame = +1
Query: 133 ALRAVGNIVTGTDEQTQVVLNCDALSHFPALLT-HPKEKICKEAVWFLSNITAGNKQQVQ 309
A+ A+GNI + VLNC L+ LLT + + + AVW LSN+ G +
Sbjct: 94 AVWALGNIAGDSSVCRDYVLNCSILNPLLTLLTKSTRLTMTRNAVWALSNLCRGKNPPPE 153
Query: 310 AVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALINCGVIPPFCNLLSC 489
+ LP++ L + +A WA+S LS G +++ A+I+ GV LL
Sbjct: 154 FAKVSPCLPVLSRLLFSSDSDLLADACWALSYLS-DGPNEKIQAVIDSGVCRRLVELLMH 212
Query: 490 KDTQVINVVLDGLSNMLKMAGDNAEQVANMIEECGGIDKIEDLQTHXKMEIYKMA 654
D +V + L + N+ + GD+ + +I C + + L + K I K A
Sbjct: 213 NDYKVASPALRAVGNI--VTGDDIQ--TQVILNCSALPCLLHLLSSPKESIRKEA 263
Score = 56.8 bits (131), Expect = 7e-08
Identities = 41/161 (25%), Positives = 73/161 (45%), Gaps = 1/161 (0%)
Frame = +1
Query: 85 PXIPLLSHKEVKVQTA-ALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEA 261
P + LL+ T A+ A+ N+ G + + L LL + +A
Sbjct: 120 PLLTLLTKSTRLTMTRNAVWALSNLCRGKNPPPEFAKVSPCLPVLSRLLFSSDSDLLADA 179
Query: 262 VWFLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAA 441
W LS ++ G +++QAVID+G+ +V L +++ A AV N+ ++G Q
Sbjct: 180 CWALSYLSDGPNEKIQAVIDSGVCRRLVELLMHNDYKVASPALRAVGNI-VTGDDIQTQV 238
Query: 442 LINCGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGDNAE 564
++NC +P +LLS + +SN+ AG+ A+
Sbjct: 239 ILNCSALPCLLHLLSSPKESIRKEACWTISNI--TAGNRAQ 277
Score = 37.9 bits (84), Expect = 0.032
Identities = 16/34 (47%), Positives = 23/34 (67%)
Frame = +3
Query: 3 DTVWAISYLTXGGNEQIQMVIXSGIVTTLXSVVV 104
D WA+SYL+ G NE+IQ VI SG+ L +++
Sbjct: 178 DACWALSYLSDGPNEKIQAVIDSGVCRRLVELLM 211
>AL135901-9|CAI40722.1| 90|Homo sapiens karyopherin alpha 3
(importin alpha 4) protein.
Length = 90
Score = 97.1 bits (231), Expect = 5e-20
Identities = 43/67 (64%), Positives = 54/67 (80%)
Frame = +1
Query: 466 PFCNLLSCKDTQVINVVLDGLSNMLKMAGDNAEQVANMIEECGGIDKIEDLQTHXKMEIY 645
PFCNLLS KD+QV+ VVLDGL N+L MAGD A +A +IEECGG++KIE LQ H +IY
Sbjct: 1 PFCNLLSVKDSQVVQVVLDGLKNILIMAGDEASTIAEIIEECGGLEKIEVLQQHENEDIY 60
Query: 646 KMAYDII 666
K+A++II
Sbjct: 61 KLAFEII 67
>AL132795-7|CAI20502.1| 121|Homo sapiens karyopherin alpha 5
(importin alpha 6) protein.
Length = 121
Score = 65.7 bits (153), Expect = 1e-10
Identities = 32/82 (39%), Positives = 51/82 (62%), Gaps = 7/82 (8%)
Frame = +1
Query: 442 LINCGVIPPFCNLLSCKDTQVINVVLDGLSNMLKMAGDNAEQ-------VANMIEECGGI 600
L+ G I P C+LL+ D++++ V L+GL N+L++ ++Q +IEE G+
Sbjct: 2 LVALGCIKPLCDLLTVMDSKIVQVALNGLENILRLGEQESKQNGIGINPYCALIEEAYGL 61
Query: 601 DKIEDLQTHXKMEIYKMAYDII 666
DKIE LQ+H EIY+ A+D+I
Sbjct: 62 DKIEFLQSHENQEIYQKAFDLI 83
>CR533552-1|CAG38583.1| 509|Homo sapiens SPAG6 protein.
Length = 509
Score = 51.6 bits (118), Expect = 2e-06
Identities = 36/151 (23%), Positives = 68/151 (45%)
Frame = +1
Query: 124 QTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWFLSNITAGNKQQ 303
QTAAL A+G + D+ + V+ CD L L K A + L + + Q
Sbjct: 59 QTAAL-ALGRLANYNDDLAEAVVKCDILPQLVYSLAEQNRFYKKAAAFVLRAVGKHSPQL 117
Query: 304 VQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALINCGVIPPFCNLL 483
QA++D G L +V L + ++ AAWA+ ++ + A+++ G +P +
Sbjct: 118 AQAIVDCGALDTLVICLEDFDPGVKEAAAWALRYIA-RHNAELSRAVVDAGAVPLLVLCI 176
Query: 484 SCKDTQVINVVLDGLSNMLKMAGDNAEQVAN 576
+ + + LS++ K + + A+ V +
Sbjct: 177 QEPEIALKRIAASALSDIAKHSPELAQTVVD 207
>AL513128-4|CAH72210.1| 509|Homo sapiens sperm associated antigen 6
protein.
Length = 509
Score = 51.6 bits (118), Expect = 2e-06
Identities = 36/151 (23%), Positives = 68/151 (45%)
Frame = +1
Query: 124 QTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWFLSNITAGNKQQ 303
QTAAL A+G + D+ + V+ CD L L K A + L + + Q
Sbjct: 59 QTAAL-ALGRLANYNDDLAEAVVKCDILPQLVYSLAEQNRFYKKAAAFVLRAVGKHSPQL 117
Query: 304 VQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALINCGVIPPFCNLL 483
QA++D G L +V L + ++ AAWA+ ++ + A+++ G +P +
Sbjct: 118 AQAIVDCGALDTLVICLEDFDPGVKEAAAWALRYIA-RHNAELSQAVVDAGAVPLLVLCI 176
Query: 484 SCKDTQVINVVLDGLSNMLKMAGDNAEQVAN 576
+ + + LS++ K + + A+ V +
Sbjct: 177 QEPEIALKRIAASALSDIAKHSPELAQTVVD 207
>AL513128-3|CAH72209.1| 458|Homo sapiens sperm associated antigen 6
protein.
Length = 458
Score = 51.6 bits (118), Expect = 2e-06
Identities = 36/151 (23%), Positives = 68/151 (45%)
Frame = +1
Query: 124 QTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWFLSNITAGNKQQ 303
QTAAL A+G + D+ + V+ CD L L K A + L + + Q
Sbjct: 59 QTAAL-ALGRLANYNDDLAEAVVKCDILPQLVYSLAEQNRFYKKAAAFVLRAVGKHSPQL 117
Query: 304 VQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALINCGVIPPFCNLL 483
QA++D G L +V L + ++ AAWA+ ++ + A+++ G +P +
Sbjct: 118 AQAIVDCGALDTLVICLEDFDPGVKEAAAWALRYIA-RHNAELSQAVVDAGAVPLLVLCI 176
Query: 484 SCKDTQVINVVLDGLSNMLKMAGDNAEQVAN 576
+ + + LS++ K + + A+ V +
Sbjct: 177 QEPEIALKRIAASALSDIAKHSPELAQTVVD 207
>AL158211-15|CAI15963.1| 509|Homo sapiens sperm associated antigen
6 protein.
Length = 509
Score = 51.6 bits (118), Expect = 2e-06
Identities = 36/151 (23%), Positives = 68/151 (45%)
Frame = +1
Query: 124 QTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWFLSNITAGNKQQ 303
QTAAL A+G + D+ + V+ CD L L K A + L + + Q
Sbjct: 59 QTAAL-ALGRLANYNDDLAEAVVKCDILPQLVYSLAEQNRFYKKAAAFVLRAVGKHSPQL 117
Query: 304 VQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALINCGVIPPFCNLL 483
QA++D G L +V L + ++ AAWA+ ++ + A+++ G +P +
Sbjct: 118 AQAIVDCGALDTLVICLEDFDPGVKEAAAWALRYIA-RHNAELSQAVVDAGAVPLLVLCI 176
Query: 484 SCKDTQVINVVLDGLSNMLKMAGDNAEQVAN 576
+ + + LS++ K + + A+ V +
Sbjct: 177 QEPEIALKRIAASALSDIAKHSPELAQTVVD 207
>AL158211-14|CAI15962.1| 458|Homo sapiens sperm associated antigen
6 protein.
Length = 458
Score = 51.6 bits (118), Expect = 2e-06
Identities = 36/151 (23%), Positives = 68/151 (45%)
Frame = +1
Query: 124 QTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWFLSNITAGNKQQ 303
QTAAL A+G + D+ + V+ CD L L K A + L + + Q
Sbjct: 59 QTAAL-ALGRLANYNDDLAEAVVKCDILPQLVYSLAEQNRFYKKAAAFVLRAVGKHSPQL 117
Query: 304 VQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALINCGVIPPFCNLL 483
QA++D G L +V L + ++ AAWA+ ++ + A+++ G +P +
Sbjct: 118 AQAIVDCGALDTLVICLEDFDPGVKEAAAWALRYIA-RHNAELSQAVVDAGAVPLLVLCI 176
Query: 484 SCKDTQVINVVLDGLSNMLKMAGDNAEQVAN 576
+ + + LS++ K + + A+ V +
Sbjct: 177 QEPEIALKRIAASALSDIAKHSPELAQTVVD 207
>AF079363-1|AAC32590.1| 509|Homo sapiens sperm flagellar protein
Repro-SA-1 protein.
Length = 509
Score = 51.6 bits (118), Expect = 2e-06
Identities = 36/151 (23%), Positives = 68/151 (45%)
Frame = +1
Query: 124 QTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWFLSNITAGNKQQ 303
QTAAL A+G + D+ + V+ CD L L K A + L + + Q
Sbjct: 59 QTAAL-ALGRLANYNDDLAEAVVKCDILPQLVYSLAEQNRFYKKAAAFVLRAVGKHSPQL 117
Query: 304 VQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALINCGVIPPFCNLL 483
QA++D G L +V L + ++ AAWA+ ++ + A+++ G +P +
Sbjct: 118 AQAIVDCGALDTLVICLEDFDPGVKEAAAWALRYIA-RHNAELSQAVVDAGAVPLLVLCI 176
Query: 484 SCKDTQVINVVLDGLSNMLKMAGDNAEQVAN 576
+ + + LS++ K + + A+ V +
Sbjct: 177 QEPEIALKRIAASALSDIAKHSPELAQTVVD 207
>BC030585-1|AAH30585.1| 458|Homo sapiens sperm associated antigen 6
protein.
Length = 458
Score = 50.8 bits (116), Expect = 4e-06
Identities = 33/152 (21%), Positives = 67/152 (44%)
Frame = +1
Query: 121 VQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWFLSNITAGNKQ 300
+Q A A+G + D+ + V+ CD L L K A + L + + Q
Sbjct: 57 IQQIAALALGRLANYNDDLAEAVVKCDILPQLVYSLAEQNRFYKKAAAFVLRAVGKHSPQ 116
Query: 301 QVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALINCGVIPPFCNL 480
QA++D G L +V L + ++ AAWA+ ++ + A+++ G +P
Sbjct: 117 LAQAIVDCGALDTLVICLEDFDPGVKEAAAWALRYIA-RHNAELSQAVVDAGAVPLLVLC 175
Query: 481 LSCKDTQVINVVLDGLSNMLKMAGDNAEQVAN 576
+ + + + LS+++K + + A+ V +
Sbjct: 176 IQEPEIALKGIAASALSDIVKHSPELAQTVVD 207
>U51269-1|AAC51202.1| 962|Homo sapiens armadillo repeat protein
protein.
Length = 962
Score = 49.6 bits (113), Expect = 1e-05
Identities = 31/107 (28%), Positives = 53/107 (49%), Gaps = 1/107 (0%)
Frame = +1
Query: 220 ALLTHPKEKICKEAVWFLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAV 399
A+L HP + + A +L ++ N+ + V LP++VA L + ++ A A+
Sbjct: 365 AMLRHPVDPVKANAAAYLQHLCFENEGVKRRVRQLRGLPLLVALLDHPRAEVRRRACGAL 424
Query: 400 SNLSISGTRDQVAALINCGVIPPFCNLL-SCKDTQVINVVLDGLSNM 537
NLS D AA+ +CG +P LL + +D +V +V L N+
Sbjct: 425 RNLSYGRDTDNKAAIRDCGGVPALVRLLRAARDNEVRELVTGTLWNL 471
>AL513128-1|CAH72207.1| 246|Homo sapiens sperm associated antigen 6
protein.
Length = 246
Score = 48.0 bits (109), Expect = 3e-05
Identities = 31/114 (27%), Positives = 53/114 (46%)
Frame = +1
Query: 124 QTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWFLSNITAGNKQQ 303
QTAAL A+G + D+ + V+ CD L L K A + L + + Q
Sbjct: 135 QTAAL-ALGRLANYNDDLAEAVVKCDILPQLVYSLAEQNRFYKKAAAFVLRAVGKHSPQL 193
Query: 304 VQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALINCGVIP 465
QA++D G L +V L + ++ AAWA+ ++ + A+++ G +P
Sbjct: 194 AQAIVDCGALDTLVICLEDFDPGVKEAAAWALRYIA-RHNAELSQAVVDAGAVP 246
>AL158211-12|CAI15960.1| 246|Homo sapiens sperm associated antigen
6 protein.
Length = 246
Score = 48.0 bits (109), Expect = 3e-05
Identities = 31/114 (27%), Positives = 53/114 (46%)
Frame = +1
Query: 124 QTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWFLSNITAGNKQQ 303
QTAAL A+G + D+ + V+ CD L L K A + L + + Q
Sbjct: 135 QTAAL-ALGRLANYNDDLAEAVVKCDILPQLVYSLAEQNRFYKKAAAFVLRAVGKHSPQL 193
Query: 304 VQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALINCGVIP 465
QA++D G L +V L + ++ AAWA+ ++ + A+++ G +P
Sbjct: 194 AQAIVDCGALDTLVICLEDFDPGVKEAAAWALRYIA-RHNAELSQAVVDAGAVP 246
>BC044907-1|AAH44907.1| 801|Homo sapiens ANKAR protein protein.
Length = 801
Score = 45.6 bits (103), Expect = 2e-04
Identities = 27/82 (32%), Positives = 41/82 (50%)
Frame = +1
Query: 259 AVWFLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVA 438
AV L I N Q + ++DAG +P ++ L + + Q + +SN IS + V
Sbjct: 484 AVMSLEVICLANDQYWRCILDAGTIPALINLLKSSKIKLQCKTVGLLSN--ISTHKSAVH 541
Query: 439 ALINCGVIPPFCNLLSCKDTQV 504
AL+ G IP NLL C + +V
Sbjct: 542 ALVEAGGIPSLINLLVCDEPEV 563
>AK126073-1|BAC86425.1| 1080|Homo sapiens protein ( Homo sapiens
cDNA FLJ44085 fis, clone TESTI4041053. ).
Length = 1080
Score = 45.6 bits (103), Expect = 2e-04
Identities = 27/82 (32%), Positives = 41/82 (50%)
Frame = +1
Query: 259 AVWFLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVA 438
AV L I N Q + ++DAG +P ++ L + + Q + +SN IS + V
Sbjct: 720 AVMSLEVICLANDQYWRCILDAGTIPALINLLKSSKIKLQCKTVGLLSN--ISTHKSAVH 777
Query: 439 ALINCGVIPPFCNLLSCKDTQV 504
AL+ G IP NLL C + +V
Sbjct: 778 ALVEAGGIPSLINLLVCDEPEV 799
>AJ549812-1|CAD71147.1| 1363|Homo sapiens hypothetical protein
protein.
Length = 1363
Score = 45.6 bits (103), Expect = 2e-04
Identities = 27/82 (32%), Positives = 41/82 (50%)
Frame = +1
Query: 259 AVWFLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVA 438
AV L I N Q + ++DAG +P ++ L + + Q + +SN IS + V
Sbjct: 649 AVMSLEVICLANDQYWRCILDAGTIPALINLLKSSKIKLQCKTVGLLSN--ISTHKSAVH 706
Query: 439 ALINCGVIPPFCNLLSCKDTQV 504
AL+ G IP NLL C + +V
Sbjct: 707 ALVEAGGIPSLINLLVCDEPEV 728
>X63465-1|CAA45067.1| 558|Homo sapiens smg GDS protein.
Length = 558
Score = 39.9 bits (89), Expect = 0.008
Identities = 40/153 (26%), Positives = 65/153 (42%), Gaps = 2/153 (1%)
Frame = +1
Query: 136 LRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWFLSNITAGNKQQVQAV 315
L+A+ T T E+ Q L F +LLT + CK V + A N+
Sbjct: 31 LQALAQNNTETSEKIQA---SGILQLFASLLT--PQSSCKAKVANIIAEVAKNEFMRIPC 85
Query: 316 IDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALINCGVIPPFCNLLS--C 489
+DAGL+ +V L+ + + + A+ N+ Q A LIN GVIP LL C
Sbjct: 86 VDAGLISPLVQLLNSKDQEVLLQTGRALGNICYDSHSLQ-AQLINMGVIPTLVKLLGIHC 144
Query: 490 KDTQVINVVLDGLSNMLKMAGDNAEQVANMIEE 588
++ + + L N+ ++ + + I E
Sbjct: 145 QNAALTEMCLVAFGNLAELESSKEQFASTNIAE 177
>BC099845-1|AAH99845.1| 559|Homo sapiens RAP1GDS1 protein protein.
Length = 559
Score = 39.9 bits (89), Expect = 0.008
Identities = 40/153 (26%), Positives = 65/153 (42%), Gaps = 2/153 (1%)
Frame = +1
Query: 136 LRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWFLSNITAGNKQQVQAV 315
L+A+ T T E+ Q L F +LLT + CK V + A N+
Sbjct: 32 LQALAQNNTETSEKIQA---SGILQLFASLLT--PQSSCKAKVANIIAEVAKNEFMRIPC 86
Query: 316 IDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALINCGVIPPFCNLLS--C 489
+DAGL+ +V L+ + + + A+ N+ Q A LIN GVIP LL C
Sbjct: 87 VDAGLISPLVQLLNSKDQEVLLQTGRALGNICYDSHSLQ-AQLINMGVIPTLVKLLGIHC 145
Query: 490 KDTQVINVVLDGLSNMLKMAGDNAEQVANMIEE 588
++ + + L N+ ++ + + I E
Sbjct: 146 QNAALTEMCLVAFGNLAELESSKEQFASTNIAE 178
>BC099708-1|AAH99708.1| 558|Homo sapiens RAP1GDS1 protein protein.
Length = 558
Score = 39.9 bits (89), Expect = 0.008
Identities = 40/153 (26%), Positives = 65/153 (42%), Gaps = 2/153 (1%)
Frame = +1
Query: 136 LRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWFLSNITAGNKQQVQAV 315
L+A+ T T E+ Q L F +LLT + CK V + A N+
Sbjct: 31 LQALAQNNTETSEKIQA---SGILQLFASLLT--PQSSCKAKVANIIAEVAKNEFMRIPC 85
Query: 316 IDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALINCGVIPPFCNLLS--C 489
+DAGL+ +V L+ + + + A+ N+ Q A LIN GVIP LL C
Sbjct: 86 VDAGLISPLVQLLNSKDQEVLLQTGRALGNICYDSHSLQ-AQLINMGVIPTLVKLLGIHC 144
Query: 490 KDTQVINVVLDGLSNMLKMAGDNAEQVANMIEE 588
++ + + L N+ ++ + + I E
Sbjct: 145 QNAALTEMCLVAFGNLAELESSKEQFASTNIAE 177
>BC098334-1|AAH98334.1| 558|Homo sapiens RAP1GDS1 protein protein.
Length = 558
Score = 39.9 bits (89), Expect = 0.008
Identities = 40/153 (26%), Positives = 65/153 (42%), Gaps = 2/153 (1%)
Frame = +1
Query: 136 LRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWFLSNITAGNKQQVQAV 315
L+A+ T T E+ Q L F +LLT + CK V + A N+
Sbjct: 31 LQALAQNNTETSEKIQA---SGILQLFASLLT--PQSSCKAKVANIIAEVAKNEFMRIPC 85
Query: 316 IDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALINCGVIPPFCNLLS--C 489
+DAGL+ +V L+ + + + A+ N+ Q A LIN GVIP LL C
Sbjct: 86 VDAGLISPLVQLLNSKDQEVLLQTGRALGNICYDSHSLQ-AQLINMGVIPTLVKLLGIHC 144
Query: 490 KDTQVINVVLDGLSNMLKMAGDNAEQVANMIEE 588
++ + + L N+ ++ + + I E
Sbjct: 145 QNAALTEMCLVAFGNLAELESSKEQFASTNIAE 177
>BC041699-1|AAH41699.1| 659|Homo sapiens armadillo repeat
containing 8 protein.
Length = 659
Score = 37.9 bits (84), Expect = 0.032
Identities = 27/104 (25%), Positives = 47/104 (45%), Gaps = 1/104 (0%)
Frame = +1
Query: 211 HFPALLTHPKEKICKEAVWFLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAA 390
H+ L P + + V + N GN +Q +I G +P ++ L + T+ +
Sbjct: 9 HYVDRLFDPDPQKVLQGVIDMKNAVIGNNKQKANLIVLGAVPRLLYLLQQETSSTELKTE 68
Query: 391 WAVSNLSIS-GTRDQVAALINCGVIPPFCNLLSCKDTQVINVVL 519
AV S++ GT + V +L++C +IP L D + I L
Sbjct: 69 CAVVLGSLAMGTENNVKSLLDCHIIPALLQGLLSPDLKFIEACL 112
Score = 30.7 bits (66), Expect = 4.9
Identities = 27/147 (18%), Positives = 56/147 (38%)
Frame = +1
Query: 100 LSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWFLSN 279
LS VKV+ AA+R + ++ + + +L + ++I A L N
Sbjct: 379 LSESSVKVRLAAVRCLHSLSRSVQQLRTSFQDHAVWKPLMKVLQNAPDEILVVASSMLCN 438
Query: 280 ITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALINCGV 459
+ + ++++G + ++ + WA+ N++ + A ++
Sbjct: 439 LLLEFSPSKEPILESGAVELLCGLTQSENPALRVNGIWALMNMAFQAEQKIKADILRSLS 498
Query: 460 IPPFCNLLSCKDTQVINVVLDGLSNML 540
LLS D V+ L L N+L
Sbjct: 499 TEQLFRLLSDSDLNVLMKTLGLLRNLL 525
>BC032661-1|AAH32661.1| 659|Homo sapiens armadillo repeat
containing 8 protein.
Length = 659
Score = 37.9 bits (84), Expect = 0.032
Identities = 27/104 (25%), Positives = 47/104 (45%), Gaps = 1/104 (0%)
Frame = +1
Query: 211 HFPALLTHPKEKICKEAVWFLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAA 390
H+ L P + + V + N GN +Q +I G +P ++ L + T+ +
Sbjct: 9 HYVDRLFDPDPQKVLQGVIDMKNAVIGNNKQKANLIVLGAVPRLLYLLQQETSSTELKTE 68
Query: 391 WAVSNLSIS-GTRDQVAALINCGVIPPFCNLLSCKDTQVINVVL 519
AV S++ GT + V +L++C +IP L D + I L
Sbjct: 69 CAVVLGSLAMGTENNVKSLLDCHIIPALLQGLLSPDLKFIEACL 112
Score = 30.7 bits (66), Expect = 4.9
Identities = 27/147 (18%), Positives = 56/147 (38%)
Frame = +1
Query: 100 LSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKICKEAVWFLSN 279
LS VKV+ AA+R + ++ + + +L + ++I A L N
Sbjct: 379 LSESSVKVRLAAVRCLHSLSRSVQQLRTSFQDHAVWKPLMKVLQNAPDEILVVASSMLCN 438
Query: 280 ITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALINCGV 459
+ + ++++G + ++ + WA+ N++ + A ++
Sbjct: 439 LLLEFSPSKEPILESGAVELLCGLTQSENPALRVNGIWALMNMAFQAEQKIKADILRSLS 498
Query: 460 IPPFCNLLSCKDTQVINVVLDGLSNML 540
LLS D V+ L L N+L
Sbjct: 499 TEQLFRLLSDSDLNVLMKTLGLLRNLL 525
>BC013424-1|AAH13424.1| 385|Homo sapiens armadillo repeat
containing 8 protein.
Length = 385
Score = 37.9 bits (84), Expect = 0.032
Identities = 27/104 (25%), Positives = 47/104 (45%), Gaps = 1/104 (0%)
Frame = +1
Query: 211 HFPALLTHPKEKICKEAVWFLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAA 390
H+ L P + + V + N GN +Q +I G +P ++ L + T+ +
Sbjct: 9 HYVDRLFDPDPQKVLQGVIDMKNAVIGNNKQKANLIVLGAVPRLLYLLQQETSSTELKTE 68
Query: 391 WAVSNLSIS-GTRDQVAALINCGVIPPFCNLLSCKDTQVINVVL 519
AV S++ GT + V +L++C +IP L D + I L
Sbjct: 69 CAVVLGSLAMGTENNVKSLLDCHIIPALLQGLLSPDLKFIEACL 112
>AK001721-1|BAA91861.1| 443|Homo sapiens protein ( Homo sapiens
cDNA FLJ10859 fis, clone NT2RP4001567, weakly similar to
ARMADILLO SEGMENT POLARITY PROTEIN. ).
Length = 443
Score = 34.3 bits (75), Expect = 0.40
Identities = 23/85 (27%), Positives = 41/85 (48%), Gaps = 2/85 (2%)
Frame = +1
Query: 271 LSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQT--QKEAAWAVSNLSISGTRDQVAAL 444
+ N GN +Q +I G +P ++ L + T + E A + +L++ GT + V +L
Sbjct: 1 MKNAVIGNNKQKANLIVLGAVPRLLYLLQQETSSTGLKTECAVVLGSLAM-GTENNVKSL 59
Query: 445 INCGVIPPFCNLLSCKDTQVINVVL 519
++C +IP L D + I L
Sbjct: 60 LDCHIIPALLQGLLSPDLKFIEACL 84
>X88824-1|CAA61294.1| 127|Homo sapiens immunoglobulin V(H) gene
V-D-J protein.
Length = 127
Score = 32.3 bits (70), Expect = 1.6
Identities = 15/49 (30%), Positives = 26/49 (53%)
Frame = +1
Query: 346 ANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALINCGVIPPFCNLLSCK 492
A+ KG F ++ A +L ++ R + AL C +IP +C+ SC+
Sbjct: 61 ADSVKGRFTISRDNAKNTLHLQMTSLRVEDTALYYCVIIPGYCSTTSCE 109
>BT007333-1|AAP35997.1| 610|Homo sapiens catenin
(cadherin-associated protein), delta 1 protein.
Length = 610
Score = 32.3 bits (70), Expect = 1.6
Identities = 24/107 (22%), Positives = 45/107 (42%), Gaps = 1/107 (0%)
Frame = +1
Query: 220 ALLTHPKEKICKEAVWFLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAV 399
A+L + + A +L ++ N + V +P++V L + + A A+
Sbjct: 50 AMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGAL 109
Query: 400 SNLSISGTRDQVAALINCGVIPPFCNLL-SCKDTQVINVVLDGLSNM 537
N+S +D A+ NC +P LL +D + V+ L N+
Sbjct: 110 KNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNL 156
>BC010501-1|AAH10501.2| 830|Homo sapiens CTNND1 protein protein.
Length = 830
Score = 32.3 bits (70), Expect = 1.6
Identities = 24/107 (22%), Positives = 45/107 (42%), Gaps = 1/107 (0%)
Frame = +1
Query: 220 ALLTHPKEKICKEAVWFLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAV 399
A+L + + A +L ++ N + V +P++V L + + A A+
Sbjct: 270 AMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGAL 329
Query: 400 SNLSISGTRDQVAALINCGVIPPFCNLL-SCKDTQVINVVLDGLSNM 537
N+S +D A+ NC +P LL +D + V+ L N+
Sbjct: 330 KNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNL 376
>AY505564-1|AAR84236.1| 941|Homo sapiens catenin
(cadherin-associated protein), delta 1 protein.
Length = 941
Score = 32.3 bits (70), Expect = 1.6
Identities = 24/107 (22%), Positives = 45/107 (42%), Gaps = 1/107 (0%)
Frame = +1
Query: 220 ALLTHPKEKICKEAVWFLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAV 399
A+L + + A +L ++ N + V +P++V L + + A A+
Sbjct: 373 AMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGAL 432
Query: 400 SNLSISGTRDQVAALINCGVIPPFCNLL-SCKDTQVINVVLDGLSNM 537
N+S +D A+ NC +P LL +D + V+ L N+
Sbjct: 433 KNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNL 479
>AF062344-1|AAC39829.1| 618|Homo sapiens p120 catenin isoform 4B
protein.
Length = 618
Score = 32.3 bits (70), Expect = 1.6
Identities = 24/107 (22%), Positives = 45/107 (42%), Gaps = 1/107 (0%)
Frame = +1
Query: 220 ALLTHPKEKICKEAVWFLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAV 399
A+L + + A +L ++ N + V +P++V L + + A A+
Sbjct: 50 AMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGAL 109
Query: 400 SNLSISGTRDQVAALINCGVIPPFCNLL-SCKDTQVINVVLDGLSNM 537
N+S +D A+ NC +P LL +D + V+ L N+
Sbjct: 110 KNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNL 156
>AF062343-1|AAC39828.1| 933|Homo sapiens p120 catenin isoform 1A
protein.
Length = 933
Score = 32.3 bits (70), Expect = 1.6
Identities = 24/107 (22%), Positives = 45/107 (42%), Gaps = 1/107 (0%)
Frame = +1
Query: 220 ALLTHPKEKICKEAVWFLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAV 399
A+L + + A +L ++ N + V +P++V L + + A A+
Sbjct: 373 AMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGAL 432
Query: 400 SNLSISGTRDQVAALINCGVIPPFCNLL-SCKDTQVINVVLDGLSNM 537
N+S +D A+ NC +P LL +D + V+ L N+
Sbjct: 433 KNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNL 479
>AF062342-1|AAC39827.1| 645|Homo sapiens p120 catenin isoform 4ABC
protein.
Length = 645
Score = 32.3 bits (70), Expect = 1.6
Identities = 24/107 (22%), Positives = 45/107 (42%), Gaps = 1/107 (0%)
Frame = +1
Query: 220 ALLTHPKEKICKEAVWFLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAV 399
A+L + + A +L ++ N + V +P++V L + + A A+
Sbjct: 50 AMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGAL 109
Query: 400 SNLSISGTRDQVAALINCGVIPPFCNLL-SCKDTQVINVVLDGLSNM 537
N+S +D A+ NC +P LL +D + V+ L N+
Sbjct: 110 KNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNL 156
>AF062341-1|AAC39826.1| 968|Homo sapiens p120 catenin isoform 1ABC
protein.
Length = 968
Score = 32.3 bits (70), Expect = 1.6
Identities = 24/107 (22%), Positives = 45/107 (42%), Gaps = 1/107 (0%)
Frame = +1
Query: 220 ALLTHPKEKICKEAVWFLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAV 399
A+L + + A +L ++ N + V +P++V L + + A A+
Sbjct: 373 AMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGAL 432
Query: 400 SNLSISGTRDQVAALINCGVIPPFCNLL-SCKDTQVINVVLDGLSNM 537
N+S +D A+ NC +P LL +D + V+ L N+
Sbjct: 433 KNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNL 479
>AF062340-1|AAC39825.1| 610|Homo sapiens p120 catenin isoform 4A
protein.
Length = 610
Score = 32.3 bits (70), Expect = 1.6
Identities = 24/107 (22%), Positives = 45/107 (42%), Gaps = 1/107 (0%)
Frame = +1
Query: 220 ALLTHPKEKICKEAVWFLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAV 399
A+L + + A +L ++ N + V +P++V L + + A A+
Sbjct: 50 AMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGAL 109
Query: 400 SNLSISGTRDQVAALINCGVIPPFCNLL-SCKDTQVINVVLDGLSNM 537
N+S +D A+ NC +P LL +D + V+ L N+
Sbjct: 110 KNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNL 156
>AF062339-1|AAC39824.1| 933|Homo sapiens p120 catenin isoform 1A
protein.
Length = 933
Score = 32.3 bits (70), Expect = 1.6
Identities = 24/107 (22%), Positives = 45/107 (42%), Gaps = 1/107 (0%)
Frame = +1
Query: 220 ALLTHPKEKICKEAVWFLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAV 399
A+L + + A +L ++ N + V +P++V L + + A A+
Sbjct: 373 AMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGAL 432
Query: 400 SNLSISGTRDQVAALINCGVIPPFCNLL-SCKDTQVINVVLDGLSNM 537
N+S +D A+ NC +P LL +D + V+ L N+
Sbjct: 433 KNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNL 479
>AF062338-1|AAC39823.1| 861|Homo sapiens p120 catenin isoform 3AB
protein.
Length = 861
Score = 32.3 bits (70), Expect = 1.6
Identities = 24/107 (22%), Positives = 45/107 (42%), Gaps = 1/107 (0%)
Frame = +1
Query: 220 ALLTHPKEKICKEAVWFLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAV 399
A+L + + A +L ++ N + V +P++V L + + A A+
Sbjct: 272 AMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGAL 331
Query: 400 SNLSISGTRDQVAALINCGVIPPFCNLL-SCKDTQVINVVLDGLSNM 537
N+S +D A+ NC +P LL +D + V+ L N+
Sbjct: 332 KNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNL 378
>AF062337-1|AAC39822.1| 838|Homo sapiens p120 catenin isoform 3AC
protein.
Length = 838
Score = 32.3 bits (70), Expect = 1.6
Identities = 24/107 (22%), Positives = 45/107 (42%), Gaps = 1/107 (0%)
Frame = +1
Query: 220 ALLTHPKEKICKEAVWFLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAV 399
A+L + + A +L ++ N + V +P++V L + + A A+
Sbjct: 272 AMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGAL 331
Query: 400 SNLSISGTRDQVAALINCGVIPPFCNLL-SCKDTQVINVVLDGLSNM 537
N+S +D A+ NC +P LL +D + V+ L N+
Sbjct: 332 KNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNL 378
>AF062336-1|AAC39821.1| 832|Homo sapiens p120 catenin isoform 3A
protein.
Length = 832
Score = 32.3 bits (70), Expect = 1.6
Identities = 24/107 (22%), Positives = 45/107 (42%), Gaps = 1/107 (0%)
Frame = +1
Query: 220 ALLTHPKEKICKEAVWFLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAV 399
A+L + + A +L ++ N + V +P++V L + + A A+
Sbjct: 272 AMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGAL 331
Query: 400 SNLSISGTRDQVAALINCGVIPPFCNLL-SCKDTQVINVVLDGLSNM 537
N+S +D A+ NC +P LL +D + V+ L N+
Sbjct: 332 KNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNL 378
>AF062335-1|AAC39820.1| 832|Homo sapiens p120 catenin isoform 3A
protein.
Length = 832
Score = 32.3 bits (70), Expect = 1.6
Identities = 24/107 (22%), Positives = 45/107 (42%), Gaps = 1/107 (0%)
Frame = +1
Query: 220 ALLTHPKEKICKEAVWFLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAV 399
A+L + + A +L ++ N + V +P++V L + + A A+
Sbjct: 272 AMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGAL 331
Query: 400 SNLSISGTRDQVAALINCGVIPPFCNLL-SCKDTQVINVVLDGLSNM 537
N+S +D A+ NC +P LL +D + V+ L N+
Sbjct: 332 KNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNL 378
>AF062334-1|AAC39819.1| 832|Homo sapiens p120 catenin isoform 3A
protein.
Length = 832
Score = 32.3 bits (70), Expect = 1.6
Identities = 24/107 (22%), Positives = 45/107 (42%), Gaps = 1/107 (0%)
Frame = +1
Query: 220 ALLTHPKEKICKEAVWFLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAV 399
A+L + + A +L ++ N + V +P++V L + + A A+
Sbjct: 272 AMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGAL 331
Query: 400 SNLSISGTRDQVAALINCGVIPPFCNLL-SCKDTQVINVVLDGLSNM 537
N+S +D A+ NC +P LL +D + V+ L N+
Sbjct: 332 KNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNL 378
>AF062333-1|AAC39818.1| 610|Homo sapiens p120 catenin isoform 4A
protein.
Length = 610
Score = 32.3 bits (70), Expect = 1.6
Identities = 24/107 (22%), Positives = 45/107 (42%), Gaps = 1/107 (0%)
Frame = +1
Query: 220 ALLTHPKEKICKEAVWFLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAV 399
A+L + + A +L ++ N + V +P++V L + + A A+
Sbjct: 50 AMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGAL 109
Query: 400 SNLSISGTRDQVAALINCGVIPPFCNLL-SCKDTQVINVVLDGLSNM 537
N+S +D A+ NC +P LL +D + V+ L N+
Sbjct: 110 KNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNL 156
>AF062332-1|AAC39817.1| 840|Homo sapiens p120 catenin isoform 3B
protein.
Length = 840
Score = 32.3 bits (70), Expect = 1.6
Identities = 24/107 (22%), Positives = 45/107 (42%), Gaps = 1/107 (0%)
Frame = +1
Query: 220 ALLTHPKEKICKEAVWFLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAV 399
A+L + + A +L ++ N + V +P++V L + + A A+
Sbjct: 272 AMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGAL 331
Query: 400 SNLSISGTRDQVAALINCGVIPPFCNLL-SCKDTQVINVVLDGLSNM 537
N+S +D A+ NC +P LL +D + V+ L N+
Sbjct: 332 KNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNL 378
>AF062331-1|AAC39816.1| 879|Homo sapiens p120 catenin isoform 2A
protein.
Length = 879
Score = 32.3 bits (70), Expect = 1.6
Identities = 24/107 (22%), Positives = 45/107 (42%), Gaps = 1/107 (0%)
Frame = +1
Query: 220 ALLTHPKEKICKEAVWFLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAV 399
A+L + + A +L ++ N + V +P++V L + + A A+
Sbjct: 319 AMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGAL 378
Query: 400 SNLSISGTRDQVAALINCGVIPPFCNLL-SCKDTQVINVVLDGLSNM 537
N+S +D A+ NC +P LL +D + V+ L N+
Sbjct: 379 KNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNL 425
>AF062330-1|AAC39815.1| 832|Homo sapiens p120 catenin isoform 3A
protein.
Length = 832
Score = 32.3 bits (70), Expect = 1.6
Identities = 24/107 (22%), Positives = 45/107 (42%), Gaps = 1/107 (0%)
Frame = +1
Query: 220 ALLTHPKEKICKEAVWFLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAV 399
A+L + + A +L ++ N + V +P++V L + + A A+
Sbjct: 272 AMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGAL 331
Query: 400 SNLSISGTRDQVAALINCGVIPPFCNLL-SCKDTQVINVVLDGLSNM 537
N+S +D A+ NC +P LL +D + V+ L N+
Sbjct: 332 KNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNL 378
>AF062329-1|AAC39814.1| 879|Homo sapiens p120 catenin isoform 2A
protein.
Length = 879
Score = 32.3 bits (70), Expect = 1.6
Identities = 24/107 (22%), Positives = 45/107 (42%), Gaps = 1/107 (0%)
Frame = +1
Query: 220 ALLTHPKEKICKEAVWFLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAV 399
A+L + + A +L ++ N + V +P++V L + + A A+
Sbjct: 319 AMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGAL 378
Query: 400 SNLSISGTRDQVAALINCGVIPPFCNLL-SCKDTQVINVVLDGLSNM 537
N+S +D A+ NC +P LL +D + V+ L N+
Sbjct: 379 KNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNL 425
>AF062328-1|AAC39813.1| 962|Homo sapiens p120 catenin isoform 1AB
protein.
Length = 962
Score = 32.3 bits (70), Expect = 1.6
Identities = 24/107 (22%), Positives = 45/107 (42%), Gaps = 1/107 (0%)
Frame = +1
Query: 220 ALLTHPKEKICKEAVWFLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAV 399
A+L + + A +L ++ N + V +P++V L + + A A+
Sbjct: 373 AMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGAL 432
Query: 400 SNLSISGTRDQVAALINCGVIPPFCNLL-SCKDTQVINVVLDGLSNM 537
N+S +D A+ NC +P LL +D + V+ L N+
Sbjct: 433 KNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNL 479
>AF062327-1|AAC39812.1| 879|Homo sapiens p120 catenin isoform 2A
protein.
Length = 879
Score = 32.3 bits (70), Expect = 1.6
Identities = 24/107 (22%), Positives = 45/107 (42%), Gaps = 1/107 (0%)
Frame = +1
Query: 220 ALLTHPKEKICKEAVWFLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAV 399
A+L + + A +L ++ N + V +P++V L + + A A+
Sbjct: 319 AMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGAL 378
Query: 400 SNLSISGTRDQVAALINCGVIPPFCNLL-SCKDTQVINVVLDGLSNM 537
N+S +D A+ NC +P LL +D + V+ L N+
Sbjct: 379 KNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNL 425
>AF062326-1|AAC39811.1| 639|Homo sapiens p120 catenin isoform 4AB
protein.
Length = 639
Score = 32.3 bits (70), Expect = 1.6
Identities = 24/107 (22%), Positives = 45/107 (42%), Gaps = 1/107 (0%)
Frame = +1
Query: 220 ALLTHPKEKICKEAVWFLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAV 399
A+L + + A +L ++ N + V +P++V L + + A A+
Sbjct: 50 AMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGAL 109
Query: 400 SNLSISGTRDQVAALINCGVIPPFCNLL-SCKDTQVINVVLDGLSNM 537
N+S +D A+ NC +P LL +D + V+ L N+
Sbjct: 110 KNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNL 156
>AF062325-1|AAC39810.1| 887|Homo sapiens p120 catenin isoform 2B
protein.
Length = 887
Score = 32.3 bits (70), Expect = 1.6
Identities = 24/107 (22%), Positives = 45/107 (42%), Gaps = 1/107 (0%)
Frame = +1
Query: 220 ALLTHPKEKICKEAVWFLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAV 399
A+L + + A +L ++ N + V +P++V L + + A A+
Sbjct: 319 AMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGAL 378
Query: 400 SNLSISGTRDQVAALINCGVIPPFCNLL-SCKDTQVINVVLDGLSNM 537
N+S +D A+ NC +P LL +D + V+ L N+
Sbjct: 379 KNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNL 425
>AF062324-1|AAC39809.1| 933|Homo sapiens p120 catenin isoform 1A
protein.
Length = 933
Score = 32.3 bits (70), Expect = 1.6
Identities = 24/107 (22%), Positives = 45/107 (42%), Gaps = 1/107 (0%)
Frame = +1
Query: 220 ALLTHPKEKICKEAVWFLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAV 399
A+L + + A +L ++ N + V +P++V L + + A A+
Sbjct: 373 AMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGAL 432
Query: 400 SNLSISGTRDQVAALINCGVIPPFCNLL-SCKDTQVINVVLDGLSNM 537
N+S +D A+ NC +P LL +D + V+ L N+
Sbjct: 433 KNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNL 479
>AF062323-1|AAC39808.1| 867|Homo sapiens p120 catenin isoform 3ABC
protein.
Length = 867
Score = 32.3 bits (70), Expect = 1.6
Identities = 24/107 (22%), Positives = 45/107 (42%), Gaps = 1/107 (0%)
Frame = +1
Query: 220 ALLTHPKEKICKEAVWFLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAV 399
A+L + + A +L ++ N + V +P++V L + + A A+
Sbjct: 272 AMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGAL 331
Query: 400 SNLSISGTRDQVAALINCGVIPPFCNLL-SCKDTQVINVVLDGLSNM 537
N+S +D A+ NC +P LL +D + V+ L N+
Sbjct: 332 KNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNL 378
>AF062322-1|AAC39807.1| 908|Homo sapiens p120 catenin isoform 2AB
protein.
Length = 908
Score = 32.3 bits (70), Expect = 1.6
Identities = 24/107 (22%), Positives = 45/107 (42%), Gaps = 1/107 (0%)
Frame = +1
Query: 220 ALLTHPKEKICKEAVWFLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAV 399
A+L + + A +L ++ N + V +P++V L + + A A+
Sbjct: 319 AMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGAL 378
Query: 400 SNLSISGTRDQVAALINCGVIPPFCNLL-SCKDTQVINVVLDGLSNM 537
N+S +D A+ NC +P LL +D + V+ L N+
Sbjct: 379 KNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNL 425
>AF062321-1|AAC39806.1| 939|Homo sapiens p120 catenin isoform 1AC
protein.
Length = 939
Score = 32.3 bits (70), Expect = 1.6
Identities = 24/107 (22%), Positives = 45/107 (42%), Gaps = 1/107 (0%)
Frame = +1
Query: 220 ALLTHPKEKICKEAVWFLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAV 399
A+L + + A +L ++ N + V +P++V L + + A A+
Sbjct: 373 AMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGAL 432
Query: 400 SNLSISGTRDQVAALINCGVIPPFCNLL-SCKDTQVINVVLDGLSNM 537
N+S +D A+ NC +P LL +D + V+ L N+
Sbjct: 433 KNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNL 479
>AF062320-1|AAC39805.1| 885|Homo sapiens p120 catenin isoform 2AC
protein.
Length = 885
Score = 32.3 bits (70), Expect = 1.6
Identities = 24/107 (22%), Positives = 45/107 (42%), Gaps = 1/107 (0%)
Frame = +1
Query: 220 ALLTHPKEKICKEAVWFLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAV 399
A+L + + A +L ++ N + V +P++V L + + A A+
Sbjct: 319 AMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGAL 378
Query: 400 SNLSISGTRDQVAALINCGVIPPFCNLL-SCKDTQVINVVLDGLSNM 537
N+S +D A+ NC +P LL +D + V+ L N+
Sbjct: 379 KNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNL 425
>AF062319-1|AAC39804.1| 914|Homo sapiens p120 catenin isoform 2ABC
protein.
Length = 914
Score = 32.3 bits (70), Expect = 1.6
Identities = 24/107 (22%), Positives = 45/107 (42%), Gaps = 1/107 (0%)
Frame = +1
Query: 220 ALLTHPKEKICKEAVWFLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAV 399
A+L + + A +L ++ N + V +P++V L + + A A+
Sbjct: 319 AMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGAL 378
Query: 400 SNLSISGTRDQVAALINCGVIPPFCNLL-SCKDTQVINVVLDGLSNM 537
N+S +D A+ NC +P LL +D + V+ L N+
Sbjct: 379 KNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNL 425
>AF062318-1|AAC39803.1| 616|Homo sapiens p120 catenin isoform 4AC
protein.
Length = 616
Score = 32.3 bits (70), Expect = 1.6
Identities = 24/107 (22%), Positives = 45/107 (42%), Gaps = 1/107 (0%)
Frame = +1
Query: 220 ALLTHPKEKICKEAVWFLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAV 399
A+L + + A +L ++ N + V +P++V L + + A A+
Sbjct: 50 AMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGAL 109
Query: 400 SNLSISGTRDQVAALINCGVIPPFCNLL-SCKDTQVINVVLDGLSNM 537
N+S +D A+ NC +P LL +D + V+ L N+
Sbjct: 110 KNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNL 156
>AF062317-1|AAC39802.1| 941|Homo sapiens p120 catenin isoform 1B
protein.
Length = 941
Score = 32.3 bits (70), Expect = 1.6
Identities = 24/107 (22%), Positives = 45/107 (42%), Gaps = 1/107 (0%)
Frame = +1
Query: 220 ALLTHPKEKICKEAVWFLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAV 399
A+L + + A +L ++ N + V +P++V L + + A A+
Sbjct: 373 AMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGAL 432
Query: 400 SNLSISGTRDQVAALINCGVIPPFCNLL-SCKDTQVINVVLDGLSNM 537
N+S +D A+ NC +P LL +D + V+ L N+
Sbjct: 433 KNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNL 479
>AB002382-1|BAA20838.2| 967|Homo sapiens KIAA0384 protein.
Length = 967
Score = 32.3 bits (70), Expect = 1.6
Identities = 24/107 (22%), Positives = 45/107 (42%), Gaps = 1/107 (0%)
Frame = +1
Query: 220 ALLTHPKEKICKEAVWFLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAV 399
A+L + + A +L ++ N + V +P++V L + + A A+
Sbjct: 401 AMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGAL 460
Query: 400 SNLSISGTRDQVAALINCGVIPPFCNLL-SCKDTQVINVVLDGLSNM 537
N+S +D A+ NC +P LL +D + V+ L N+
Sbjct: 461 KNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNL 507
>BC075795-1|AAH75795.1| 933|Homo sapiens CTNND1 protein protein.
Length = 933
Score = 31.5 bits (68), Expect = 2.8
Identities = 18/70 (25%), Positives = 32/70 (45%), Gaps = 1/70 (1%)
Frame = +1
Query: 331 LPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQVAALINCGVIPPFCNLL-SCKDTQVI 507
+P++V L + + A A+ N+S +D A+ NC +P LL +D +
Sbjct: 410 IPVLVGLLDHPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLT 469
Query: 508 NVVLDGLSNM 537
V+ L N+
Sbjct: 470 EVITGTLWNL 479
>Z19054-1|CAA79497.1| 781|Homo sapiens beta catenin protein.
Length = 781
Score = 30.3 bits (65), Expect = 6.5
Identities = 32/155 (20%), Positives = 61/155 (39%), Gaps = 3/155 (1%)
Frame = +1
Query: 82 QPXIPLLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNC---DALSHFPALLTHPKEKIC 252
Q + LL+ VK + + G E ++L AL + T+ K
Sbjct: 280 QKMVALLNKTNVKFLAITTDCLQILAYGNQESKLIILASGGPQALVNIMRTYTYEKLLWT 339
Query: 253 KEAVWFLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQ 432
V + ++ + NK A+++AG + + +L+ + + W + NLS + T+ +
Sbjct: 340 TSRVLKVLSVCSSNKP---AIVEAGGMQALGLHLTDPSQRLVQNCLWTLRNLSDAATKQE 396
Query: 433 VAALINCGVIPPFCNLLSCKDTQVINVVLDGLSNM 537
G++ LL D V+ LSN+
Sbjct: 397 GME----GLLGTLVQLLGSDDINVVTCAAGILSNL 427
>Y07818-1|CAA69153.1| 570|Homo sapiens ULIP protein.
Length = 570
Score = 30.3 bits (65), Expect = 6.5
Identities = 11/29 (37%), Positives = 15/29 (51%)
Frame = +3
Query: 366 VSNPEGSCLGRFQPQHQWHEGPSCCTYQL 452
V PE S ++ +W +G SCC Y L
Sbjct: 109 VPEPESSLTEAYEKWREWADGKSCCDYAL 137
>X87838-1|CAA61107.1| 781|Homo sapiens beta-catenin protein.
Length = 781
Score = 30.3 bits (65), Expect = 6.5
Identities = 32/155 (20%), Positives = 61/155 (39%), Gaps = 3/155 (1%)
Frame = +1
Query: 82 QPXIPLLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNC---DALSHFPALLTHPKEKIC 252
Q + LL+ VK + + G E ++L AL + T+ K
Sbjct: 280 QKMVALLNKTNVKFLAITTDCLQILAYGNQESKLIILASGGPQALVNIMRTYTYEKLLWT 339
Query: 253 KEAVWFLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQ 432
V + ++ + NK A+++AG + + +L+ + + W + NLS + T+ +
Sbjct: 340 TSRVLKVLSVCSSNKP---AIVEAGGMQALGLHLTDPSQRLVQNCLWTLRNLSDAATKQE 396
Query: 433 VAALINCGVIPPFCNLLSCKDTQVINVVLDGLSNM 537
G++ LL D V+ LSN+
Sbjct: 397 GME----GLLGTLVQLLGSDDINVVTCAAGILSNL 427
>D78014-1|BAA11192.1| 570|Homo sapiens dihydropyrimidinase related
protein-3 protein.
Length = 570
Score = 30.3 bits (65), Expect = 6.5
Identities = 11/29 (37%), Positives = 15/29 (51%)
Frame = +3
Query: 366 VSNPEGSCLGRFQPQHQWHEGPSCCTYQL 452
V PE S ++ +W +G SCC Y L
Sbjct: 109 VPEPESSLTEAYEKWREWADGKSCCDYAL 137
>BC077077-1|AAH77077.1| 684|Homo sapiens DPYSL3 protein protein.
Length = 684
Score = 30.3 bits (65), Expect = 6.5
Identities = 11/29 (37%), Positives = 15/29 (51%)
Frame = +3
Query: 366 VSNPEGSCLGRFQPQHQWHEGPSCCTYQL 452
V PE S ++ +W +G SCC Y L
Sbjct: 223 VPEPESSLTEAYEKWREWADGKSCCDYAL 251
>BC058926-1|AAH58926.1| 781|Homo sapiens catenin
(cadherin-associated protein), beta 1, 88kDa protein.
Length = 781
Score = 30.3 bits (65), Expect = 6.5
Identities = 32/155 (20%), Positives = 61/155 (39%), Gaps = 3/155 (1%)
Frame = +1
Query: 82 QPXIPLLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNC---DALSHFPALLTHPKEKIC 252
Q + LL+ VK + + G E ++L AL + T+ K
Sbjct: 280 QKMVALLNKTNVKFLAITTDCLQILAYGNQESKLIILASGGPQALVNIMRTYTYEKLLWT 339
Query: 253 KEAVWFLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQ 432
V + ++ + NK A+++AG + + +L+ + + W + NLS + T+ +
Sbjct: 340 TSRVLKVLSVCSSNKP---AIVEAGGMQALGLHLTDPSQRLVQNCLWTLRNLSDAATKQE 396
Query: 433 VAALINCGVIPPFCNLLSCKDTQVINVVLDGLSNM 537
G++ LL D V+ LSN+
Sbjct: 397 GME----GLLGTLVQLLGSDDINVVTCAAGILSNL 427
>BC039006-1|AAH39006.1| 570|Homo sapiens dihydropyrimidinase-like 3
protein.
Length = 570
Score = 30.3 bits (65), Expect = 6.5
Identities = 11/29 (37%), Positives = 15/29 (51%)
Frame = +3
Query: 366 VSNPEGSCLGRFQPQHQWHEGPSCCTYQL 452
V PE S ++ +W +G SCC Y L
Sbjct: 109 VPEPESSLTEAYEKWREWADGKSCCDYAL 137
>AY463360-1|AAR18817.1| 781|Homo sapiens catenin
(cadherin-associated protein), beta 1, 88kDa protein.
Length = 781
Score = 30.3 bits (65), Expect = 6.5
Identities = 32/155 (20%), Positives = 61/155 (39%), Gaps = 3/155 (1%)
Frame = +1
Query: 82 QPXIPLLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNC---DALSHFPALLTHPKEKIC 252
Q + LL+ VK + + G E ++L AL + T+ K
Sbjct: 280 QKMVALLNKTNVKFLAITTDCLQILAYGNQESKLIILASGGPQALVNIMRTYTYEKLLWT 339
Query: 253 KEAVWFLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQ 432
V + ++ + NK A+++AG + + +L+ + + W + NLS + T+ +
Sbjct: 340 TSRVLKVLSVCSSNKP---AIVEAGGMQALGLHLTDPSQRLVQNCLWTLRNLSDAATKQE 396
Query: 433 VAALINCGVIPPFCNLLSCKDTQVINVVLDGLSNM 537
G++ LL D V+ LSN+
Sbjct: 397 GME----GLLGTLVQLLGSDDINVVTCAAGILSNL 427
>AB062292-1|BAB93475.1| 511|Homo sapiens catenin beta 1 protein.
Length = 511
Score = 30.3 bits (65), Expect = 6.5
Identities = 32/155 (20%), Positives = 61/155 (39%), Gaps = 3/155 (1%)
Frame = +1
Query: 82 QPXIPLLSHKEVKVQTAALRAVGNIVTGTDEQTQVVLNC---DALSHFPALLTHPKEKIC 252
Q + LL+ VK + + G E ++L AL + T+ K
Sbjct: 10 QKMVALLNKTNVKFLAITTDCLQILAYGNQESKLIILASGGPQALVNIMRTYTYEKLLWT 69
Query: 253 KEAVWFLSNITAGNKQQVQAVIDAGLLPMIVANLSKGEFQTQKEAAWAVSNLSISGTRDQ 432
V + ++ + NK A+++AG + + +L+ + + W + NLS + T+ +
Sbjct: 70 TSRVLKVLSVCSSNKP---AIVEAGGMQALGLHLTDPSQRLVQNCLWTLRNLSDAATKQE 126
Query: 433 VAALINCGVIPPFCNLLSCKDTQVINVVLDGLSNM 537
G++ LL D V+ LSN+
Sbjct: 127 GME----GLLGTLVQLLGSDDINVVTCAAGILSNL 157
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 102,497,025
Number of Sequences: 237096
Number of extensions: 2251478
Number of successful extensions: 4946
Number of sequences better than 10.0: 103
Number of HSP's better than 10.0 without gapping: 4344
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4762
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 7535049140
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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