Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P14_F_G15
(796 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
U37143-1|AAC50370.2| 502|Homo sapiens cytochrome P450 monooxyge... 100 7e-21
BC032594-1|AAH32594.1| 502|Homo sapiens cytochrome P450, family... 100 7e-21
AY426985-1|AAQ93356.1| 502|Homo sapiens cytochrome P450, family... 100 7e-21
AF272142-1|AAM44456.1| 502|Homo sapiens cytochrome P450 protein. 100 7e-21
AB080265-1|BAB85489.1| 502|Homo sapiens cytochrome P450 2J2 pro... 100 7e-21
AF144566-1|AAD30164.1| 339|Homo sapiens cytochrome P450 epoxyge... 99 2e-20
EF122242-1|ABO41977.1| 321|Homo sapiens cytochrome P450 2F1 var... 94 5e-19
J02906-1|AAA52156.1| 491|Homo sapiens CYP2F1 protein. 92 2e-18
EF122241-1|ABO41976.1| 491|Homo sapiens cytochrome P450 2F1 var... 91 4e-18
BC109056-1|AAI09057.1| 320|Homo sapiens CYP2F1 protein protein. 91 4e-18
AF372573-1|AAL69652.1| 495|Homo sapiens cytochrome P450 2F1 pro... 91 4e-18
M61854-1|AAB59426.1| 490|Homo sapiens cytochrome protein. 87 5e-17
AY796203-1|AAV41877.1| 490|Homo sapiens cytochrome P450, family... 87 5e-17
AL583836-2|CAH74068.1| 490|Homo sapiens cytochrome P450, family... 87 5e-17
AL133513-2|CAH73444.1| 490|Homo sapiens cytochrome P450, family... 87 5e-17
Y00498-1|CAA68550.1| 490|Homo sapiens IIC2 protein. 87 9e-17
J02843-1|AAA52155.1| 493|Homo sapiens protein ( Human cytochrom... 87 9e-17
J02625-1|AAA35743.1| 493|Homo sapiens protein ( Human cytochrom... 87 9e-17
DQ515958-1|ABF47105.1| 493|Homo sapiens cytochrome P450, family... 87 9e-17
DQ149222-1|AAZ77710.1| 493|Homo sapiens cytochrome P450 2E1 pro... 87 9e-17
BC067435-1|AAH67435.1| 493|Homo sapiens cytochrome P450, family... 87 9e-17
AY514490-1|AAR89907.1| 490|Homo sapiens cytochrome P450, family... 87 9e-17
AL359672-5|CAH71307.1| 490|Homo sapiens cytochrome P450, family... 87 9e-17
AL161645-2|CAH70047.1| 493|Homo sapiens cytochrome P450, family... 87 9e-17
AF182276-1|AAF13601.1| 493|Homo sapiens cytochrome P450-2E1 pro... 87 9e-17
M21941-1|AAA52160.1| 480|Homo sapiens CYP2C protein. 86 1e-16
BC067433-1|AAH67433.1| 493|Homo sapiens cytochrome P450, family... 86 1e-16
BC020596-1|AAH20596.1| 490|Homo sapiens cytochrome P450, family... 86 1e-16
M17398-1|AAA35740.1| 393|Homo sapiens protein ( Human cytochrom... 86 2e-16
M17397-1|AAA35739.1| 490|Homo sapiens protein ( Human cytochrom... 86 2e-16
M29874-1|AAA52144.1| 491|Homo sapiens CYP2B protein. 85 3e-16
DQ298753-1|ABB84469.1| 491|Homo sapiens cytochrome P450, family... 85 3e-16
BC067431-1|AAH67431.1| 491|Homo sapiens cytochrome P450, family... 85 3e-16
AC023172-1|AAF32444.1| 491|Homo sapiens CYP2B6 protein. 85 3e-16
BC067430-1|AAH67430.1| 491|Homo sapiens cytochrome P450, family... 85 4e-16
AY513608-1|AAR90939.1| 494|Homo sapiens cytochrome P450 2A13 va... 83 8e-16
AF182277-1|AAF13602.1| 491|Homo sapiens cytochrome P450-2B6 pro... 83 8e-16
S46963-1|AAB23864.2| 477|Homo sapiens cytochrome P-450 protein. 83 1e-15
M29873-1|AAA52143.1| 377|Homo sapiens CYP2B protein. 83 1e-15
M21942-1|AAA52161.1| 462|Homo sapiens CYP2C protein. 83 1e-15
M21939-1|AAA52158.1| 485|Homo sapiens CYP2C protein. 83 1e-15
M15331-1|AAA52157.1| 485|Homo sapiens CYP2C protein. 83 1e-15
L16880-1|AAD13466.1| 273|Homo sapiens cytochrome P-450 2C protein. 83 1e-15
D00173-1|BAA00123.1| 487|Homo sapiens cytochrome P-450 protein. 83 1e-15
BC125054-1|AAI25055.1| 490|Homo sapiens cytochrome P450, family... 83 1e-15
BC041174-1|AAH41174.1| 377|Homo sapiens CYP2B7P1 protein protein. 83 1e-15
AY702706-1|AAT94065.1| 490|Homo sapiens cytochrome P450, family... 83 1e-15
AY341248-1|AAP88931.1| 490|Homo sapiens cytochrome P450, family... 83 1e-15
AL359672-1|CAH71303.1| 490|Homo sapiens cytochrome P450, family... 83 1e-15
AF084225-1|AAD13753.1| 462|Homo sapiens cytochrome P450 2E1 pro... 83 1e-15
BC033691-1|AAH33691.1| 504|Homo sapiens cytochrome P450, family... 83 1e-15
AY358603-1|AAQ88966.1| 504|Homo sapiens Cytochrome p450 protein. 83 1e-15
AK027605-1|BAB55227.1| 564|Homo sapiens protein ( Homo sapiens ... 83 1e-15
AF335278-1|AAK13498.1| 504|Homo sapiens cytochrome P450 2S1 pro... 83 1e-15
X13897-1|CAA32097.1| 489|Homo sapiens protein ( Human mRNA for ... 82 2e-15
U22028-1|AAB40519.1| 494|Homo sapiens cytochrome P450 protein. 82 2e-15
M33318-1|AAA52067.1| 494|Homo sapiens CYP2A protein. 82 2e-15
BC117165-1|AAI17166.1| 494|Homo sapiens cytochrome P450, family... 82 2e-15
BC104909-1|AAI04910.1| 501|Homo sapiens cytochrome P450, family... 82 2e-15
BC104907-1|AAI04908.1| 501|Homo sapiens cytochrome P450, family... 82 2e-15
BC096256-1|AAH96256.1| 494|Homo sapiens cytochrome P450, family... 82 2e-15
BC096254-1|AAH96254.1| 494|Homo sapiens cytochrome P450, family... 82 2e-15
BC096253-1|AAH96253.3| 494|Homo sapiens cytochrome P450, family... 82 2e-15
AY513609-1|AAR90940.1| 494|Homo sapiens cytochrome P450 2A13 va... 82 2e-15
AY513606-1|AAR90937.1| 494|Homo sapiens cytochrome P450 2A13 va... 82 2e-15
AY513605-1|AAR90936.1| 494|Homo sapiens cytochrome P450 2A13 va... 82 2e-15
AY513604-1|AAR90935.1| 494|Homo sapiens cytochrome P450 2A13 va... 82 2e-15
AY323817-1|AAQ23114.1| 501|Homo sapiens cytochrome P450 2R1 pro... 82 2e-15
AF209774-1|AAG35775.1| 494|Homo sapiens cytochrome P450 2A13 pr... 82 2e-15
AF182275-1|AAF13600.1| 494|Homo sapiens cytochrome P450-2A6 pro... 82 2e-15
U22027-1|AAB40518.1| 494|Homo sapiens cytochrome P450 protein. 81 3e-15
AY871801-1|AAX62803.1| 483|Homo sapiens cytochrome P450 family ... 81 3e-15
AK223108-1|BAD96828.1| 512|Homo sapiens cytochrome P450, family... 81 3e-15
X04300-1|CAA27843.1| 512|Homo sapiens P-450 c protein. 81 5e-15
X02612-1|CAA26458.1| 512|Homo sapiens cytochrome P(1)-450 protein. 81 5e-15
U22029-1|AAB40520.1| 494|Homo sapiens cytochrome P450 protein. 81 5e-15
K03191-1|AAA52139.1| 512|Homo sapiens CYP1A1 protein. 81 5e-15
EF094025-1|ABK41999.1| 512|Homo sapiens cytochrome P450, family... 81 5e-15
BC023019-1|AAH23019.1| 512|Homo sapiens cytochrome P450, family... 81 5e-15
AY310359-1|AAQ76692.1| 484|Homo sapiens cytochrome P450 1A1 var... 81 5e-15
AM236046-1|CAJ84703.1| 229|Homo sapiens cytochrome P450 1A1 pro... 81 5e-15
AF253322-1|AAK25727.1| 512|Homo sapiens cytochrome P450 protein. 81 5e-15
X13930-1|CAA32118.1| 494|Homo sapiens protein ( Human CYP2A4 mR... 80 8e-15
M61856-1|AAB59356.1| 490|Homo sapiens cytochrome protein. 80 8e-15
L16876-1|AAA02630.1| 490|Homo sapiens cytochrome P-4502C18 prot... 80 8e-15
BC096260-1|AAH96260.1| 431|Homo sapiens CYP2C18 protein protein. 80 8e-15
BC096259-1|AAH96259.1| 443|Homo sapiens CYP2C18 protein protein. 80 8e-15
BC096258-1|AAH96258.1| 490|Homo sapiens cytochrome P450, family... 80 8e-15
BC096257-1|AAH96257.1| 490|Homo sapiens cytochrome P450, family... 80 8e-15
BC096255-1|AAH96255.1| 494|Homo sapiens cytochrome P450, family... 80 8e-15
BC069666-1|AAH69666.1| 490|Homo sapiens cytochrome P450, family... 80 8e-15
AL583836-1|CAH74067.1| 490|Homo sapiens cytochrome P450, family... 80 8e-15
AF182274-1|AAF13599.1| 516|Homo sapiens cytochrome P450-1A2 pro... 79 1e-14
Z00036-1|CAA77335.1| 515|Homo sapiens protein ( Human mRNA for ... 79 2e-14
M55053-1|AAA52146.1| 515|Homo sapiens cytochrome P3-450 protein. 79 2e-14
M33317-1|AAA52138.1| 494|Homo sapiens CYP2A protein. 79 2e-14
M31667-1|AAA52163.1| 515|Homo sapiens CYP1A2 protein. 79 2e-14
DQ022432-1|AAY26399.1| 516|Homo sapiens cytochrome P450, family... 79 2e-14
BC067429-1|AAH67429.1| 516|Homo sapiens cytochrome P450, family... 79 2e-14
BC067428-1|AAH67428.1| 516|Homo sapiens cytochrome P450, family... 79 2e-14
BC067426-1|AAH67426.1| 516|Homo sapiens cytochrome P450, family... 79 2e-14
BC067425-1|AAH67425.1| 516|Homo sapiens cytochrome P450, family... 79 2e-14
BC067424-1|AAH67424.1| 516|Homo sapiens cytochrome P450, family... 79 2e-14
AM233520-1|CAJ80723.1| 189|Homo sapiens cytochrome P450 1A1 pro... 79 2e-14
AM233519-1|CAJ80722.1| 189|Homo sapiens cytochrome P450 1A1 pro... 79 2e-14
AF253322-2|AAK25728.1| 516|Homo sapiens cytochrome P450 protein. 79 2e-14
L00389-1|AAA35738.1| 516|Homo sapiens protein ( Human cytochrom... 78 3e-14
AK223113-1|BAD96833.1| 512|Homo sapiens cytochrome P450, family... 78 3e-14
L39098-1|AAL31347.1| 160|Homo sapiens S-mephenytoin 4-hydroxyla... 78 4e-14
AK223510-1|BAD97230.1| 490|Homo sapiens cytochrome P450, family... 78 4e-14
BC067427-1|AAH67427.1| 516|Homo sapiens cytochrome P450, family... 76 1e-13
S63426-1|ABB76283.1| 214|Homo sapiens (S)-mephenytoin hydroxyla... 76 2e-13
BC020754-1|AAH20754.1| 162|Homo sapiens CYP2C9 protein protein. 73 9e-13
BC070317-1|AAH70317.1| 162|Homo sapiens CYP2C9 protein protein. 72 3e-12
M63871-1|AAA59984.1| 508|Homo sapiens CYP17 protein. 70 8e-12
M19489-1|AAA36405.1| 508|Homo sapiens CYP17 protein. 70 8e-12
M14564-1|AAA52151.1| 508|Homo sapiens CYP17 protein. 70 8e-12
DQ530598-1|ABF50972.1| 508|Homo sapiens cytochrome P450, family... 70 8e-12
BT020000-1|AAV38803.1| 508|Homo sapiens cytochrome P450, family... 70 8e-12
BC063388-1|AAH63388.1| 508|Homo sapiens cytochrome P450, family... 70 8e-12
BC062997-1|AAH62997.1| 508|Homo sapiens cytochrome P450, family... 70 8e-12
AL358790-3|CAI52498.1| 508|Homo sapiens cytochrome P450, family... 70 8e-12
M31153-1|AAA52140.1| 508|Homo sapiens CYP17 protein. 70 1e-11
X13929-1|CAA32117.1| 448|Homo sapiens P-450 IIA3 protein (1 is ... 67 8e-11
BC132767-1|AAI32768.1| 544|Homo sapiens cytochrome P450, family... 64 4e-10
AY343323-1|AAQ21380.1| 544|Homo sapiens cytochrome P450 protein. 64 4e-10
L07093-1|AAA36660.1| 468|Homo sapiens cytochrome P450 protein. 64 6e-10
BT020001-1|AAV38804.1| 543|Homo sapiens cytochrome P450, family... 64 6e-10
U56438-1|AAC50809.1| 543|Homo sapiens dioxin-inducible cytochro... 64 7e-10
U03688-1|AAA19567.1| 543|Homo sapiens cytochrome P450 protein. 64 7e-10
DQ359216-1|ABC95161.1| 347|Homo sapiens dioxin-inducible cytoch... 64 7e-10
BT019979-1|AAV38782.1| 543|Homo sapiens cytochrome P450, family... 64 7e-10
BC012049-1|AAH12049.1| 543|Homo sapiens cytochrome P450, family... 64 7e-10
AY393998-1|AAQ87875.1| 543|Homo sapiens cytochrome P450, family... 64 7e-10
AF450132-1|AAM50512.1| 543|Homo sapiens cytochrome P450 CYP1B1 ... 64 7e-10
AC009229-2|AAY15039.1| 543|Homo sapiens unknown protein. 64 7e-10
BC025761-1|AAH25761.2| 490|Homo sapiens cytochrome P450, family... 60 7e-09
X08006-1|CAA30807.1| 497|Homo sapiens cytochrome P450 db1 protein. 54 6e-07
M33388-1|AAA53500.1| 497|Homo sapiens cytochrome P450 IID6 prot... 54 6e-07
M20403-1|AAA52153.1| 497|Homo sapiens CYP2D protein. 54 6e-07
DQ282160-1|ABB77908.1| 497|Homo sapiens cytochrome P450 2D6 pro... 54 6e-07
DQ282159-1|ABB77907.1| 497|Homo sapiens cytochrome P450 2D6 pro... 54 6e-07
DQ282156-1|ABB77904.1| 497|Homo sapiens cytochrome P450 2D6 pro... 54 6e-07
DQ282155-1|ABB77903.1| 497|Homo sapiens cytochrome P450 2D6 pro... 54 6e-07
DQ282154-1|ABB77902.1| 497|Homo sapiens cytochrome P450 2D6 pro... 54 6e-07
DQ282151-1|ABB77899.1| 496|Homo sapiens cytochrome P450 2D6 pro... 54 6e-07
DQ282147-1|ABB77898.1| 497|Homo sapiens cytochrome P450 2D6 pro... 54 6e-07
DQ282146-1|ABB77897.1| 497|Homo sapiens cytochrome P450 2D6 pro... 54 6e-07
DQ282145-1|ABB77896.1| 497|Homo sapiens cytochrome P450 2D6 pro... 54 6e-07
DQ282144-1|ABB77895.1| 497|Homo sapiens cytochrome P450 2D6 pro... 54 6e-07
BC126858-1|AAI26859.1| 497|Homo sapiens cytochrome P450, family... 54 6e-07
BC106758-1|AAI06759.1| 497|Homo sapiens cytochrome P450, family... 54 6e-07
BC075024-1|AAH75024.1| 497|Homo sapiens cytochrome P450, family... 54 6e-07
BC075023-1|AAH75023.1| 497|Homo sapiens cytochrome P450, family... 54 6e-07
BC067432-1|AAH67432.1| 497|Homo sapiens cytochrome P450, family... 54 6e-07
AY545216-1|AAS55001.1| 497|Homo sapiens cytochrome P4502D6 prot... 54 6e-07
DQ282153-1|ABB77901.1| 497|Homo sapiens cytochrome P450 2D6 pro... 54 8e-07
AY220845-1|AAO49806.1| 516|Homo sapiens cytochrome P450 protein. 53 1e-06
DQ282162-1|ABB77909.1| 500|Homo sapiens cytochrome P450 2D6 pro... 52 2e-06
DQ282158-1|ABB77906.1| 497|Homo sapiens cytochrome P450 2D6 pro... 52 3e-06
DQ282157-1|ABB77905.1| 497|Homo sapiens cytochrome P450 2D6 pro... 52 3e-06
DQ282152-1|ABB77900.1| 497|Homo sapiens cytochrome P450 2D6 pro... 51 4e-06
DQ211354-2|ABB01372.1| 497|Homo sapiens cytochrome P450 2D6 pro... 51 4e-06
DQ211353-2|ABB01371.1| 497|Homo sapiens cytochrome P450 2D6 pro... 51 4e-06
DQ211353-1|ABB01370.1| 497|Homo sapiens cytochrome P450 2D6 pro... 51 4e-06
AY513607-1|AAR90938.1| 100|Homo sapiens truncated cytochrome P4... 44 5e-04
AK000366-1|BAA91114.1| 408|Homo sapiens protein ( Homo sapiens ... 44 5e-04
DQ372705-1|ABD16216.1| 150|Homo sapiens mutant cytochrome p450 ... 42 0.002
M21940-1|AAA52159.1| 383|Homo sapiens CYP2C protein. 42 0.003
AF171066-1|AAG43404.1| 112|Homo sapiens CYP1B1 variant protein. 40 0.008
AB209492-1|BAD92729.1| 566|Homo sapiens Debrisoquine 4-hydroxyl... 40 0.008
BC012027-1|AAH12027.1| 168|Homo sapiens CYP2U1 protein protein. 35 0.29
BC109084-1|AAI09085.1| 448|Homo sapiens CYP24A1 protein protein. 31 3.6
BC109083-1|AAI09084.1| 448|Homo sapiens CYP24A1 protein protein. 31 3.6
AL138805-3|CAM27343.1| 448|Homo sapiens cytochrome P450, family... 31 3.6
AL138805-2|CAB91829.1| 514|Homo sapiens cytochrome P450, family... 31 3.6
M61858-1|AAA52145.1| 370|Homo sapiens CYP2C17 protein. 31 4.8
L13286-1|AAA62379.1| 513|Homo sapiens 1,25-dihydroxyvitamin D3 ... 31 4.8
BC036233-1|AAH36233.1| 946|Homo sapiens WDR66 protein protein. 31 4.8
BC028421-1|AAH28421.1| 1154|Homo sapiens WD repeat domain 66 pro... 31 4.8
EF122245-1|ABO41980.1| 54|Homo sapiens cytochrome P450 2F1 var... 31 6.3
BX538127-1|CAD98029.1| 310|Homo sapiens hypothetical protein pr... 31 6.3
X58908-1|CAA41711.1| 97|Homo sapiens steroid 21-monooxygenase ... 30 8.4
BC024324-1|AAH24324.1| 440|Homo sapiens TNRC6A protein protein. 30 8.4
AY035864-1|AAK62026.1| 1709|Homo sapiens GW182 autoantigen protein. 30 8.4
AK001773-1|BAA91899.1| 440|Homo sapiens protein ( Homo sapiens ... 30 8.4
AJ492221-1|CAD37348.1| 1962|Homo sapiens EDIE protein protein. 30 8.4
AB040893-1|BAA95984.1| 1400|Homo sapiens KIAA1460 protein protein. 30 8.4
>U37143-1|AAC50370.2| 502|Homo sapiens cytochrome P450
monooxygenase CYP2J2 protein.
Length = 502
Score = 100 bits (239), Expect = 7e-21
Identities = 54/186 (29%), Positives = 96/186 (51%), Gaps = 2/186 (1%)
Frame = +2
Query: 218 FKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSD 397
F K + +N PPGPW LP +G +D H+ + K YG ++ L++G I AV+++
Sbjct: 34 FLKRRRPKNYPPGPWRLPFLGNFFLVDFEQSHLEVQLFVKKYGNLFSLELGDISAVLITG 93
Query: 398 HKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSKH 571
L+++A +F R + + NG+I + G W++QR+ + L++FG+ K
Sbjct: 94 LPLIKEALIHMDQNFGNRPVTPMREHIFKKNGLIMSSGQAWKEQRRFTLTALRNFGLGKK 153
Query: 572 SVSREKLEKRIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGFKFPPEDKTW 751
S LE+RI + E I++ + D + N++ N++ I FG +F +D
Sbjct: 154 S-----LEERIQEEAQHLTEAIKEENGQPFDPHFKINNAVSNIICSITFGERFEYQD--- 205
Query: 752 QWFRQI 769
WF+Q+
Sbjct: 206 SWFQQL 211
>BC032594-1|AAH32594.1| 502|Homo sapiens cytochrome P450, family 2,
subfamily J, polypeptide 2 protein.
Length = 502
Score = 100 bits (239), Expect = 7e-21
Identities = 54/186 (29%), Positives = 96/186 (51%), Gaps = 2/186 (1%)
Frame = +2
Query: 218 FKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSD 397
F K + +N PPGPW LP +G +D H+ + K YG ++ L++G I AV+++
Sbjct: 34 FLKRRRPKNYPPGPWRLPFLGNFFLVDFEQSHLEVQLFVKKYGNLFSLELGDISAVLITG 93
Query: 398 HKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSKH 571
L+++A +F R + + NG+I + G W++QR+ + L++FG+ K
Sbjct: 94 LPLIKEALIHMDQNFGNRPVTPMREHIFKKNGLIMSSGQAWKEQRRFTLTALRNFGLGKK 153
Query: 572 SVSREKLEKRIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGFKFPPEDKTW 751
S LE+RI + E I++ + D + N++ N++ I FG +F +D
Sbjct: 154 S-----LEERIQEEAQHLTEAIKEENGQPFDPHFKINNAVSNIICSITFGERFEYQD--- 205
Query: 752 QWFRQI 769
WF+Q+
Sbjct: 206 SWFQQL 211
>AY426985-1|AAQ93356.1| 502|Homo sapiens cytochrome P450, family 2,
subfamily J, polypeptide 2 protein.
Length = 502
Score = 100 bits (239), Expect = 7e-21
Identities = 54/186 (29%), Positives = 96/186 (51%), Gaps = 2/186 (1%)
Frame = +2
Query: 218 FKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSD 397
F K + +N PPGPW LP +G +D H+ + K YG ++ L++G I AV+++
Sbjct: 34 FLKRRRPKNYPPGPWRLPFLGNFFLVDFEQSHLEVQLFVKKYGNLFSLELGDISAVLITG 93
Query: 398 HKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSKH 571
L+++A +F R + + NG+I + G W++QR+ + L++FG+ K
Sbjct: 94 LPLIKEALIHMDQNFGNRPVTPMREHIFKKNGLIMSSGQAWKEQRRFTLTALRNFGLGKK 153
Query: 572 SVSREKLEKRIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGFKFPPEDKTW 751
S LE+RI + E I++ + D + N++ N++ I FG +F +D
Sbjct: 154 S-----LEERIQEEAQHLTEAIKEENGQPFDPHFKINNAVSNIICSITFGERFEYQD--- 205
Query: 752 QWFRQI 769
WF+Q+
Sbjct: 206 SWFQQL 211
>AF272142-1|AAM44456.1| 502|Homo sapiens cytochrome P450 protein.
Length = 502
Score = 100 bits (239), Expect = 7e-21
Identities = 54/186 (29%), Positives = 96/186 (51%), Gaps = 2/186 (1%)
Frame = +2
Query: 218 FKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSD 397
F K + +N PPGPW LP +G +D H+ + K YG ++ L++G I AV+++
Sbjct: 34 FLKRRRPKNYPPGPWRLPFLGNFFLVDFEQSHLEVQLFVKKYGNLFSLELGDISAVLITG 93
Query: 398 HKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSKH 571
L+++A +F R + + NG+I + G W++QR+ + L++FG+ K
Sbjct: 94 LPLIKEALIHMDQNFGNRPVTPMREHIFKKNGLIMSSGQAWKEQRRFTLTALRNFGLGKK 153
Query: 572 SVSREKLEKRIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGFKFPPEDKTW 751
S LE+RI + E I++ + D + N++ N++ I FG +F +D
Sbjct: 154 S-----LEERIQEEAQHLTEAIKEENGQPFDPHFKINNAVSNIICSITFGERFEYQD--- 205
Query: 752 QWFRQI 769
WF+Q+
Sbjct: 206 SWFQQL 211
>AB080265-1|BAB85489.1| 502|Homo sapiens cytochrome P450 2J2
protein.
Length = 502
Score = 100 bits (239), Expect = 7e-21
Identities = 54/186 (29%), Positives = 96/186 (51%), Gaps = 2/186 (1%)
Frame = +2
Query: 218 FKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSD 397
F K + +N PPGPW LP +G +D H+ + K YG ++ L++G I AV+++
Sbjct: 34 FLKRRRPKNYPPGPWRLPFLGNFFLVDFEQSHLEVQLFVKKYGNLFSLELGDISAVLITG 93
Query: 398 HKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSKH 571
L+++A +F R + + NG+I + G W++QR+ + L++FG+ K
Sbjct: 94 LPLIKEALIHMDQNFGNRPVTPMREHIFKKNGLIMSSGQAWKEQRRFTLTALRNFGLGKK 153
Query: 572 SVSREKLEKRIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGFKFPPEDKTW 751
S LE+RI + E I++ + D + N++ N++ I FG +F +D
Sbjct: 154 S-----LEERIQEEAQHLTEAIKEENGQPFDPHFKINNAVSNIICSITFGERFEYQD--- 205
Query: 752 QWFRQI 769
WF+Q+
Sbjct: 206 SWFQQL 211
>AF144566-1|AAD30164.1| 339|Homo sapiens cytochrome P450
epoxygenase protein.
Length = 339
Score = 98.7 bits (235), Expect = 2e-20
Identities = 53/186 (28%), Positives = 96/186 (51%), Gaps = 2/186 (1%)
Frame = +2
Query: 218 FKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSD 397
F K + +N PPGPW LP +G +D H+ + K YG ++ L++G I AV+++
Sbjct: 3 FLKRRRPKNYPPGPWRLPFLGNFFLVDFEQSHLEVQLFVKKYGNLFSLELGDISAVLITG 62
Query: 398 HKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSKH 571
L+++A +F R + + NG+I + G W++QR+ + L++FG+ K
Sbjct: 63 LPLIKEALIHMDQNFGNRPVTPMREHIFKKNGLIMSSGQAWKEQRRFTLTALRNFGLGK- 121
Query: 572 SVSREKLEKRIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGFKFPPEDKTW 751
+ LE+RI + E I++ + D + N++ N++ I FG +F +D
Sbjct: 122 ----KGLEERIQEEAQHLTEAIKEENGQPFDPHFKINNAVSNIICSITFGERFEYQD--- 174
Query: 752 QWFRQI 769
WF+Q+
Sbjct: 175 SWFQQL 180
>EF122242-1|ABO41977.1| 321|Homo sapiens cytochrome P450 2F1
variant protein.
Length = 321
Score = 94.3 bits (224), Expect = 5e-19
Identities = 56/169 (33%), Positives = 88/169 (52%), Gaps = 2/169 (1%)
Frame = +2
Query: 245 LPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAF- 421
LPPGP LPI+G L + +LT LSK YG++Y + +G VVLS ++ V++A
Sbjct: 30 LPPGPRPLPILGNLLLLCSQDMLTSLTKLSKEYGSMYTVHLGPRRVVVLSGYQAVKEALV 89
Query: 422 -SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSKHSVSREKLEK 598
+ FSGR GNGI + G W+ R+ L++FGM K S+ LE+
Sbjct: 90 DQGEEFSGRGDYPAFFNFTKGNGIAFSSGDRWKVLRQFSIQILRNFGMGKRSIEERILEE 149
Query: 599 RIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGFKFPPEDK 745
G + +L + KT D +L+ S+ N++ ++FG +F +D+
Sbjct: 150 ----GSF-LLAELRKTEGEPFDPTFVLSRSVSNIICSVLFGSRFDYDDE 193
>J02906-1|AAA52156.1| 491|Homo sapiens CYP2F1 protein.
Length = 491
Score = 91.9 bits (218), Expect = 2e-18
Identities = 55/169 (32%), Positives = 88/169 (52%), Gaps = 2/169 (1%)
Frame = +2
Query: 245 LPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAF- 421
LPPGP L I+G L + +LT LSK YG++Y + +G VVLS ++ V++A
Sbjct: 30 LPPGPRPLSILGNLLLLCSQDMLTSLTKLSKEYGSMYTVHLGPRRVVVLSGYQAVKEALV 89
Query: 422 -SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSKHSVSREKLEK 598
+ FSGR GNGI + G W+ R+ L++FGM K S+ LE+
Sbjct: 90 DQGEEFSGRGDYPAFFNFTKGNGIAFSSGDRWKVLRQFSIQILRNFGMGKRSIEERILEE 149
Query: 599 RIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGFKFPPEDK 745
G + +L ++ KT D +L+ S+ N++ ++FG +F +D+
Sbjct: 150 ----GSF-LLADVRKTEGEPFDPTFVLSRSVSNIICSVLFGSRFDYDDE 193
>EF122241-1|ABO41976.1| 491|Homo sapiens cytochrome P450 2F1
variant protein.
Length = 491
Score = 91.1 bits (216), Expect = 4e-18
Identities = 55/169 (32%), Positives = 87/169 (51%), Gaps = 2/169 (1%)
Frame = +2
Query: 245 LPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAF- 421
LPPGP L I+G L + +LT LSK YG++Y + +G VVLS ++ V++A
Sbjct: 30 LPPGPRPLSILGNLLLLCSQDMLTSLTKLSKEYGSMYTVHLGPRRVVVLSGYQAVKEALV 89
Query: 422 -SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSKHSVSREKLEK 598
+ FSGR GNGI + G W+ R+ L++FGM K S+ LE+
Sbjct: 90 DQGEEFSGRGDYPAFFNFTKGNGIAFSSGDRWKVLRQFSIQILRNFGMGKRSIEERILEE 149
Query: 599 RIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGFKFPPEDK 745
G + +L + KT D +L+ S+ N++ ++FG +F +D+
Sbjct: 150 ----GSF-LLAELRKTEGEPFDPTFVLSRSVSNIICSVLFGSRFDYDDE 193
>BC109056-1|AAI09057.1| 320|Homo sapiens CYP2F1 protein protein.
Length = 320
Score = 91.1 bits (216), Expect = 4e-18
Identities = 55/169 (32%), Positives = 87/169 (51%), Gaps = 2/169 (1%)
Frame = +2
Query: 245 LPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAF- 421
LPPGP L I+G L + +LT LSK YG++Y + +G VVLS ++ V++A
Sbjct: 30 LPPGPRPLSILGNLLLLCSQDMLTSLTKLSKEYGSMYTVHLGPRRVVVLSGYQAVKEALV 89
Query: 422 -SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSKHSVSREKLEK 598
+ FSGR GNGI + G W+ R+ L++FGM K S+ LE+
Sbjct: 90 DQGEEFSGRGDYPAFFNFTKGNGIAFSSGDRWKVLRQFSIQILRNFGMGKRSIEERILEE 149
Query: 599 RIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGFKFPPEDK 745
G + +L + KT D +L+ S+ N++ ++FG +F +D+
Sbjct: 150 ----GSF-LLAELRKTEGEPFDPTFVLSRSVSNIICSVLFGSRFDYDDE 193
>AF372573-1|AAL69652.1| 495|Homo sapiens cytochrome P450 2F1
protein.
Length = 495
Score = 91.1 bits (216), Expect = 4e-18
Identities = 55/169 (32%), Positives = 87/169 (51%), Gaps = 2/169 (1%)
Frame = +2
Query: 245 LPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAF- 421
LPPGP L I+G L + +LT LSK YG++Y + +G VVLS ++ V++A
Sbjct: 30 LPPGPRPLSILGNLLLLCSQDMLTSLTKLSKEYGSMYTVHLGPRRVVVLSGYQAVKEALV 89
Query: 422 -SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSKHSVSREKLEK 598
+ FSGR GNGI + G W+ R+ L++FGM K S+ LE+
Sbjct: 90 DQGEEFSGRGDYPAFFNFTKGNGIAFSSGDRWKVLRQFSIQILRNFGMGKRSIEERILEE 149
Query: 599 RIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGFKFPPEDK 745
G + +L + KT D +L+ S+ N++ ++FG +F +D+
Sbjct: 150 ----GSF-LLAELRKTEGEPFDPTFVLSRSVSNIICSVLFGSRFDYDDE 193
>M61854-1|AAB59426.1| 490|Homo sapiens cytochrome protein.
Length = 490
Score = 87.4 bits (207), Expect = 5e-17
Identities = 56/169 (33%), Positives = 87/169 (51%), Gaps = 2/169 (1%)
Frame = +2
Query: 245 LPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFS 424
LPPGP LP++G + ID +LTNLSK YG ++ L G VVL +++V++A
Sbjct: 29 LPPGPTPLPVIGNILQIDIKDVSKSLTNLSKIYGPVFTLYFGLERMVVLHGYEVVKEALI 88
Query: 425 K--DSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSKHSVSREKLEK 598
+ FSGR L G GI+ + G W++ R+ L++FGM K S+ E
Sbjct: 89 DLGEEFSGRGHFPLAERANRGFGIVFSNGKRWKEIRRFSLMTLRNFGMGKRSI-----ED 143
Query: 599 RIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGFKFPPEDK 745
R+ ++E + KT + D +L + NV+ IIF +F +D+
Sbjct: 144 RVQEEARCLVEELRKTKASPCDPTFILGCAPCNVICSIIFQKRFDYKDQ 192
>AY796203-1|AAV41877.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 19 protein.
Length = 490
Score = 87.4 bits (207), Expect = 5e-17
Identities = 56/169 (33%), Positives = 87/169 (51%), Gaps = 2/169 (1%)
Frame = +2
Query: 245 LPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFS 424
LPPGP LP++G + ID +LTNLSK YG ++ L G VVL +++V++A
Sbjct: 29 LPPGPTPLPVIGNILQIDIKDVSKSLTNLSKIYGPVFTLYFGLERMVVLHGYEVVKEALI 88
Query: 425 K--DSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSKHSVSREKLEK 598
+ FSGR L G GI+ + G W++ R+ L++FGM K S+ E
Sbjct: 89 DLGEEFSGRGHFPLAERANRGFGIVFSNGKRWKEIRRFSLMTLRNFGMGKRSI-----ED 143
Query: 599 RIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGFKFPPEDK 745
R+ ++E + KT + D +L + NV+ IIF +F +D+
Sbjct: 144 RVQEEARCLVEELRKTKASPCDPTFILGCAPCNVICSIIFQKRFDYKDQ 192
>AL583836-2|CAH74068.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 19 protein.
Length = 490
Score = 87.4 bits (207), Expect = 5e-17
Identities = 56/169 (33%), Positives = 87/169 (51%), Gaps = 2/169 (1%)
Frame = +2
Query: 245 LPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFS 424
LPPGP LP++G + ID +LTNLSK YG ++ L G VVL +++V++A
Sbjct: 29 LPPGPTPLPVIGNILQIDIKDVSKSLTNLSKIYGPVFTLYFGLERMVVLHGYEVVKEALI 88
Query: 425 K--DSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSKHSVSREKLEK 598
+ FSGR L G GI+ + G W++ R+ L++FGM K S+ E
Sbjct: 89 DLGEEFSGRGHFPLAERANRGFGIVFSNGKRWKEIRRFSLMTLRNFGMGKRSI-----ED 143
Query: 599 RIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGFKFPPEDK 745
R+ ++E + KT + D +L + NV+ IIF +F +D+
Sbjct: 144 RVQEEARCLVEELRKTKASPCDPTFILGCAPCNVICSIIFQKRFDYKDQ 192
>AL133513-2|CAH73444.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 19 protein.
Length = 490
Score = 87.4 bits (207), Expect = 5e-17
Identities = 56/169 (33%), Positives = 87/169 (51%), Gaps = 2/169 (1%)
Frame = +2
Query: 245 LPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFS 424
LPPGP LP++G + ID +LTNLSK YG ++ L G VVL +++V++A
Sbjct: 29 LPPGPTPLPVIGNILQIDIKDVSKSLTNLSKIYGPVFTLYFGLERMVVLHGYEVVKEALI 88
Query: 425 K--DSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSKHSVSREKLEK 598
+ FSGR L G GI+ + G W++ R+ L++FGM K S+ E
Sbjct: 89 DLGEEFSGRGHFPLAERANRGFGIVFSNGKRWKEIRRFSLMTLRNFGMGKRSI-----ED 143
Query: 599 RIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGFKFPPEDK 745
R+ ++E + KT + D +L + NV+ IIF +F +D+
Sbjct: 144 RVQEEARCLVEELRKTKASPCDPTFILGCAPCNVICSIIFQKRFDYKDQ 192
>Y00498-1|CAA68550.1| 490|Homo sapiens IIC2 protein.
Length = 490
Score = 86.6 bits (205), Expect = 9e-17
Identities = 53/189 (28%), Positives = 99/189 (52%), Gaps = 2/189 (1%)
Frame = +2
Query: 191 VTFVAGFWIFKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMG 370
++F+ F ++++ + LPPGP LPI+G + ID + TN SK YG ++ + G
Sbjct: 11 LSFMLLFSLWRQSCRRRKLPPGPTPLPIIGNMLQIDVKDICKSFTNFSKVYGPVFTVYFG 70
Query: 371 SIYAVVLSDHKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSW 544
VV ++ V++A + + FSGR ++ + G GII + G W++ R+ +
Sbjct: 71 MNPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNGKRWKEIRRFSLTT 130
Query: 545 LKSFGMSKHSVSREKLEKRIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGF 724
L++FGM K S+ E R+ + ++E + KT + D +L + NV+ ++F
Sbjct: 131 LRNFGMGKRSI-----EDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQK 185
Query: 725 KFPPEDKTW 751
+F +D+ +
Sbjct: 186 RFDYKDQNF 194
>J02843-1|AAA52155.1| 493|Homo sapiens protein ( Human cytochrome
P450IIE1 (ethanol-inducible) gene, complete cds. ).
Length = 493
Score = 86.6 bits (205), Expect = 9e-17
Identities = 59/206 (28%), Positives = 102/206 (49%), Gaps = 2/206 (0%)
Frame = +2
Query: 182 IWLVTFVAGFWIFKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGL 361
+W F+ +++++ NLPPGP+ LPI+G L ++ + + T L++ +G ++ L
Sbjct: 12 VW-AAFLLLVSMWRQVHSSWNLPPGPFPLPIIGNLFQLELKNIPKSFTRLAQRFGPVFTL 70
Query: 362 KMGSIYAVVLSDHKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLI 535
+GS VV+ +K V++A KD FSGR L H GII G W+D R+
Sbjct: 71 YVGSQRMVVMHGYKAVKEALLDYKDEFSGRGDLPAFHA-HRDRGIIFNNGPTWKDIRRFS 129
Query: 536 TSWLKSFGMSKHSVSREKLEKRIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEII 715
+ L+++GM K + E RI + +LE + KT D ++ + NV+ +I+
Sbjct: 130 LTTLRNYGMGK-----QGNESRIQREAHFLLEALRKTQGQPFDPTFLIGCAPCNVIADIL 184
Query: 716 FGFKFPPEDKTWQWFRQIQEEGCHXM 793
F F D+ + + E H +
Sbjct: 185 FRKHFDYNDEKFLRLMYLFNENFHLL 210
>J02625-1|AAA35743.1| 493|Homo sapiens protein ( Human cytochrome
P-450j mRNA, complete cds. ).
Length = 493
Score = 86.6 bits (205), Expect = 9e-17
Identities = 59/206 (28%), Positives = 102/206 (49%), Gaps = 2/206 (0%)
Frame = +2
Query: 182 IWLVTFVAGFWIFKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGL 361
+W F+ +++++ NLPPGP+ LPI+G L ++ + + T L++ +G ++ L
Sbjct: 12 VW-AAFLLLVSMWRQVHSSWNLPPGPFPLPIIGNLFQLELKNIPKSFTRLAQRFGPVFTL 70
Query: 362 KMGSIYAVVLSDHKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLI 535
+GS VV+ +K V++A KD FSGR L H GII G W+D R+
Sbjct: 71 YVGSQRMVVMHGYKAVKEALLDYKDEFSGRGDLPAFHA-HRDRGIIFNNGPTWKDIRRFS 129
Query: 536 TSWLKSFGMSKHSVSREKLEKRIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEII 715
+ L+++GM K + E RI + +LE + KT D ++ + NV+ +I+
Sbjct: 130 LTTLRNYGMGK-----QGNESRIQREAHFLLEALRKTQGQPFDPTFLIGCAPCNVIADIL 184
Query: 716 FGFKFPPEDKTWQWFRQIQEEGCHXM 793
F F D+ + + E H +
Sbjct: 185 FRKHFDYNDEKFLRLMYLFNENFHLL 210
>DQ515958-1|ABF47105.1| 493|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 1 protein.
Length = 493
Score = 86.6 bits (205), Expect = 9e-17
Identities = 59/206 (28%), Positives = 102/206 (49%), Gaps = 2/206 (0%)
Frame = +2
Query: 182 IWLVTFVAGFWIFKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGL 361
+W F+ +++++ NLPPGP+ LPI+G L ++ + + T L++ +G ++ L
Sbjct: 12 VW-AAFLLLVSMWRQVHSSWNLPPGPFPLPIIGNLFQLELKNIPKSFTRLAQRFGPVFTL 70
Query: 362 KMGSIYAVVLSDHKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLI 535
+GS VV+ +K V++A KD FSGR L H GII G W+D R+
Sbjct: 71 YVGSQRMVVMHGYKAVKEALLDYKDEFSGRGDLPAFHA-HRDRGIIFNNGPTWKDIRRFS 129
Query: 536 TSWLKSFGMSKHSVSREKLEKRIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEII 715
+ L+++GM K + E RI + +LE + KT D ++ + NV+ +I+
Sbjct: 130 LTTLRNYGMGK-----QGNESRIQREAHFLLEALRKTQGQPFDPTFLIGCAPCNVIADIL 184
Query: 716 FGFKFPPEDKTWQWFRQIQEEGCHXM 793
F F D+ + + E H +
Sbjct: 185 FRKHFDYNDEKFLRLMYLFNENFHLL 210
>DQ149222-1|AAZ77710.1| 493|Homo sapiens cytochrome P450 2E1
protein.
Length = 493
Score = 86.6 bits (205), Expect = 9e-17
Identities = 59/206 (28%), Positives = 102/206 (49%), Gaps = 2/206 (0%)
Frame = +2
Query: 182 IWLVTFVAGFWIFKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGL 361
+W F+ +++++ NLPPGP+ LPI+G L ++ + + T L++ +G ++ L
Sbjct: 12 VW-AAFLLLVSMWRQVHSSWNLPPGPFPLPIIGNLFQLELKNIPKSFTRLAQRFGPVFTL 70
Query: 362 KMGSIYAVVLSDHKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLI 535
+GS VV+ +K V++A KD FSGR L H GII G W+D R+
Sbjct: 71 YVGSQRMVVMHGYKAVKEALLDYKDEFSGRGDLPAFHA-HRDRGIIFNNGPTWKDIRRFS 129
Query: 536 TSWLKSFGMSKHSVSREKLEKRIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEII 715
+ L+++GM K + E RI + +LE + KT D ++ + NV+ +I+
Sbjct: 130 LTTLRNYGMGK-----QGNESRIQREAHFLLEALRKTQGQPFDPTFLIGCAPCNVIADIL 184
Query: 716 FGFKFPPEDKTWQWFRQIQEEGCHXM 793
F F D+ + + E H +
Sbjct: 185 FRKHFDYNDEKFLRLMYLFNENFHLL 210
>BC067435-1|AAH67435.1| 493|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 1 protein.
Length = 493
Score = 86.6 bits (205), Expect = 9e-17
Identities = 59/206 (28%), Positives = 102/206 (49%), Gaps = 2/206 (0%)
Frame = +2
Query: 182 IWLVTFVAGFWIFKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGL 361
+W F+ +++++ NLPPGP+ LPI+G L ++ + + T L++ +G ++ L
Sbjct: 12 VW-AAFLLLVSMWRQVHSSWNLPPGPFPLPIIGNLFQLELKNIPKSFTRLAQRFGPVFTL 70
Query: 362 KMGSIYAVVLSDHKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLI 535
+GS VV+ +K V++A KD FSGR L H GII G W+D R+
Sbjct: 71 YVGSQRMVVMHGYKAVKEALLDYKDEFSGRGDLPAFHA-HRDRGIIFNNGPAWKDIRRFS 129
Query: 536 TSWLKSFGMSKHSVSREKLEKRIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEII 715
+ L+++GM K + E RI + +LE + KT D ++ + NV+ +I+
Sbjct: 130 LTTLRNYGMGK-----QGNESRIQREAHFLLEALRKTQGQPFDPTFLIGCAPCNVIADIL 184
Query: 716 FGFKFPPEDKTWQWFRQIQEEGCHXM 793
F F D+ + + E H +
Sbjct: 185 FRKHFDYNDEKFLRLMYLFNENFHLL 210
>AY514490-1|AAR89907.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 8 protein.
Length = 490
Score = 86.6 bits (205), Expect = 9e-17
Identities = 53/189 (28%), Positives = 99/189 (52%), Gaps = 2/189 (1%)
Frame = +2
Query: 191 VTFVAGFWIFKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMG 370
++F+ F ++++ + LPPGP LPI+G + ID + TN SK YG ++ + G
Sbjct: 11 LSFMLLFSLWRQSCRRRKLPPGPTPLPIIGNMLQIDVKDICKSFTNFSKVYGPVFTVYFG 70
Query: 371 SIYAVVLSDHKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSW 544
VV ++ V++A + + FSGR ++ + G GII + G W++ R+ +
Sbjct: 71 MNPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNGKRWKEIRRFSLTT 130
Query: 545 LKSFGMSKHSVSREKLEKRIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGF 724
L++FGM K S+ E R+ + ++E + KT + D +L + NV+ ++F
Sbjct: 131 LRNFGMGKRSI-----EDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQK 185
Query: 725 KFPPEDKTW 751
+F +D+ +
Sbjct: 186 RFDYKDQNF 194
>AL359672-5|CAH71307.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 8 protein.
Length = 490
Score = 86.6 bits (205), Expect = 9e-17
Identities = 53/189 (28%), Positives = 99/189 (52%), Gaps = 2/189 (1%)
Frame = +2
Query: 191 VTFVAGFWIFKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMG 370
++F+ F ++++ + LPPGP LPI+G + ID + TN SK YG ++ + G
Sbjct: 11 LSFMLLFSLWRQSCRRRKLPPGPTPLPIIGNMLQIDVKDICKSFTNFSKVYGPVFTVYFG 70
Query: 371 SIYAVVLSDHKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSW 544
VV ++ V++A + + FSGR ++ + G GII + G W++ R+ +
Sbjct: 71 MNPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNGKRWKEIRRFSLTT 130
Query: 545 LKSFGMSKHSVSREKLEKRIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGF 724
L++FGM K S+ E R+ + ++E + KT + D +L + NV+ ++F
Sbjct: 131 LRNFGMGKRSI-----EDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQK 185
Query: 725 KFPPEDKTW 751
+F +D+ +
Sbjct: 186 RFDYKDQNF 194
>AL161645-2|CAH70047.1| 493|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 1 protein.
Length = 493
Score = 86.6 bits (205), Expect = 9e-17
Identities = 59/206 (28%), Positives = 102/206 (49%), Gaps = 2/206 (0%)
Frame = +2
Query: 182 IWLVTFVAGFWIFKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGL 361
+W F+ +++++ NLPPGP+ LPI+G L ++ + + T L++ +G ++ L
Sbjct: 12 VW-AAFLLLVSMWRQVHSSWNLPPGPFPLPIIGNLFQLELKNIPKSFTRLAQRFGPVFTL 70
Query: 362 KMGSIYAVVLSDHKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLI 535
+GS VV+ +K V++A KD FSGR L H GII G W+D R+
Sbjct: 71 YVGSQRMVVMHGYKAVKEALLDYKDEFSGRGDLPAFHA-HRDRGIIFNNGPTWKDIRRFS 129
Query: 536 TSWLKSFGMSKHSVSREKLEKRIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEII 715
+ L+++GM K + E RI + +LE + KT D ++ + NV+ +I+
Sbjct: 130 LTTLRNYGMGK-----QGNESRIQREAHFLLEALRKTQGQPFDPTFLIGCAPCNVIADIL 184
Query: 716 FGFKFPPEDKTWQWFRQIQEEGCHXM 793
F F D+ + + E H +
Sbjct: 185 FRKHFDYNDEKFLRLMYLFNENFHLL 210
>AF182276-1|AAF13601.1| 493|Homo sapiens cytochrome P450-2E1
protein.
Length = 493
Score = 86.6 bits (205), Expect = 9e-17
Identities = 59/206 (28%), Positives = 102/206 (49%), Gaps = 2/206 (0%)
Frame = +2
Query: 182 IWLVTFVAGFWIFKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGL 361
+W F+ +++++ NLPPGP+ LPI+G L ++ + + T L++ +G ++ L
Sbjct: 12 VW-AAFLLLVSMWRQVHSSWNLPPGPFPLPIIGNLFQLELKNIPKSFTRLAQRFGPVFTL 70
Query: 362 KMGSIYAVVLSDHKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLI 535
+GS VV+ +K V++A KD FSGR L H GII G W+D R+
Sbjct: 71 YVGSQRMVVMHGYKAVKEALLDYKDEFSGRGDLPAFHA-HRDRGIIFNNGPTWKDIRRFS 129
Query: 536 TSWLKSFGMSKHSVSREKLEKRIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEII 715
+ L+++GM K + E RI + +LE + KT D ++ + NV+ +I+
Sbjct: 130 LTTLRNYGMGK-----QGNESRIQREAHFLLEALRKTQGQPFDPTFLIGCAPCNVIADIL 184
Query: 716 FGFKFPPEDKTWQWFRQIQEEGCHXM 793
F F D+ + + E H +
Sbjct: 185 FRKHFDYNDEKFLRLMYLFNENFHLL 210
>M21941-1|AAA52160.1| 480|Homo sapiens CYP2C protein.
Length = 480
Score = 86.2 bits (204), Expect = 1e-16
Identities = 53/187 (28%), Positives = 98/187 (52%), Gaps = 2/187 (1%)
Frame = +2
Query: 191 VTFVAGFWIFKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMG 370
++F+ F ++++ + LPPGP LPI+G + ID + TN SK YG ++ + G
Sbjct: 1 LSFMLLFSLWRQSCRRRKLPPGPTPLPIIGNMLQIDVKDICKSFTNFSKVYGPVFTVYFG 60
Query: 371 SIYAVVLSDHKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSW 544
VV ++ V++A + + FSGR ++ + G GII + G W++ R+ +
Sbjct: 61 MNPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNGKRWKEIRRFSLTT 120
Query: 545 LKSFGMSKHSVSREKLEKRIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGF 724
L++FGM K S+ E R+ + ++E + KT + D +L + NV+ ++F
Sbjct: 121 LRNFGMGKRSI-----EDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQK 175
Query: 725 KFPPEDK 745
+F +D+
Sbjct: 176 RFDYKDQ 182
>BC067433-1|AAH67433.1| 493|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 1 protein.
Length = 493
Score = 86.2 bits (204), Expect = 1e-16
Identities = 59/206 (28%), Positives = 102/206 (49%), Gaps = 2/206 (0%)
Frame = +2
Query: 182 IWLVTFVAGFWIFKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGL 361
+W F+ +++++ NLPPGP+ LPI+G L ++ + + T L++ +G ++ L
Sbjct: 12 VW-AAFLLLVSMWRQVHSSWNLPPGPFPLPIIGNLFQLELKNIPKSFTRLAQRFGPVFTL 70
Query: 362 KMGSIYAVVLSDHKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLI 535
+GS VV+ +K V++A KD FSGR L H GII G W+D R+
Sbjct: 71 CVGSQRMVVMHGYKAVKEALLDYKDEFSGRGDLPAFHA-HRDRGIIFNNGPTWKDIRRFS 129
Query: 536 TSWLKSFGMSKHSVSREKLEKRIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEII 715
+ L+++GM K + E RI + +LE + KT D ++ + NV+ +I+
Sbjct: 130 LTTLRNYGMGK-----QGNESRIQREAHFLLEALRKTQGQPFDPTFLIGCAPCNVIADIL 184
Query: 716 FGFKFPPEDKTWQWFRQIQEEGCHXM 793
F F D+ + + E H +
Sbjct: 185 FRKHFDYNDEKFLRLMYLFNENFHLL 210
>BC020596-1|AAH20596.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 8 protein.
Length = 490
Score = 86.2 bits (204), Expect = 1e-16
Identities = 53/189 (28%), Positives = 99/189 (52%), Gaps = 2/189 (1%)
Frame = +2
Query: 191 VTFVAGFWIFKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMG 370
++F+ F ++++ + LPPGP LPI+G + ID + TN SK YG ++ + G
Sbjct: 11 LSFMLLFSLWRQSCRRRKLPPGPTPLPIIGNMLQIDVKDICKSFTNFSKVYGPVFTVYFG 70
Query: 371 SIYAVVLSDHKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSW 544
VV ++ V++A + + FSGR ++ + G GII + G W++ R+ +
Sbjct: 71 MNPIVVFHGYESVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNGKRWKEIRRFSLTT 130
Query: 545 LKSFGMSKHSVSREKLEKRIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGF 724
L++FGM K S+ E R+ + ++E + KT + D +L + NV+ ++F
Sbjct: 131 LRNFGMGKRSI-----EDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQK 185
Query: 725 KFPPEDKTW 751
+F +D+ +
Sbjct: 186 RFDYKDQNF 194
>M17398-1|AAA35740.1| 393|Homo sapiens protein ( Human cytochrome
P-450 1 mRNA, complete cds, clone Hp1-2. ).
Length = 393
Score = 85.8 bits (203), Expect = 2e-16
Identities = 53/189 (28%), Positives = 99/189 (52%), Gaps = 2/189 (1%)
Frame = +2
Query: 191 VTFVAGFWIFKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMG 370
++F+ F ++++ + LPPGP LPI+G + ID + TN SK YG ++ + G
Sbjct: 11 LSFMLLFSLWRQSCRRRKLPPGPTPLPIIGNMLQIDVKDICKSFTNFSKVYGPVFTVYFG 70
Query: 371 SIYAVVLSDHKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSW 544
VV ++ V++A + + FSGR ++ + G GII + G W++ R+ +
Sbjct: 71 MNPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNGKRWKEIRRFSLTN 130
Query: 545 LKSFGMSKHSVSREKLEKRIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGF 724
L++FGM K S+ E R+ + ++E + KT + D +L + NV+ ++F
Sbjct: 131 LRNFGMGKRSI-----EDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQK 185
Query: 725 KFPPEDKTW 751
+F +D+ +
Sbjct: 186 RFDYKDQNF 194
>M17397-1|AAA35739.1| 490|Homo sapiens protein ( Human cytochrome
P-450 1 functional form mRNA, complete cds. ).
Length = 490
Score = 85.8 bits (203), Expect = 2e-16
Identities = 53/189 (28%), Positives = 99/189 (52%), Gaps = 2/189 (1%)
Frame = +2
Query: 191 VTFVAGFWIFKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMG 370
++F+ F ++++ + LPPGP LPI+G + ID + TN SK YG ++ + G
Sbjct: 11 LSFMLLFSLWRQSCRRRKLPPGPTPLPIIGNMLQIDVKDICKSFTNFSKVYGPVFTVYFG 70
Query: 371 SIYAVVLSDHKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSW 544
VV ++ V++A + + FSGR ++ + G GII + G W++ R+ +
Sbjct: 71 MNPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNGKRWKEIRRFSLTN 130
Query: 545 LKSFGMSKHSVSREKLEKRIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGF 724
L++FGM K S+ E R+ + ++E + KT + D +L + NV+ ++F
Sbjct: 131 LRNFGMGKRSI-----EDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQK 185
Query: 725 KFPPEDKTW 751
+F +D+ +
Sbjct: 186 RFDYKDQNF 194
>M29874-1|AAA52144.1| 491|Homo sapiens CYP2B protein.
Length = 491
Score = 85.0 bits (201), Expect = 3e-16
Identities = 52/193 (26%), Positives = 94/193 (48%), Gaps = 2/193 (1%)
Frame = +2
Query: 173 LYFIWLVTFVAGFWIFKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAI 352
L F+ L+T + + + LPPGP LP++G L +DR + + YG +
Sbjct: 6 LLFLALLTGLLLLLVQRHPNTHDRLPPGPRPLPLLGNLLQMDRRGLLKSFLRFREKYGDV 65
Query: 353 YGLKMGSIYAVVLSDHKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQR 526
+ + +G V+L + +R+A ++FSGR + + G G+I A G W+ R
Sbjct: 66 FTVHLGPRPVVMLCGVEAIREALVDKAEAFSGRGKIAMVDPFFRGYGVIFANGNRWKVLR 125
Query: 527 KLITSWLKSFGMSKHSVSREKLEKRIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVN 706
+ + ++ FGM K SV E+RI ++E + K+ A +D + + N++
Sbjct: 126 RFSVTTMRDFGMGKRSV-----EERIQEEAQCLIEELRKSKGALMDPTFLFQSITANIIC 180
Query: 707 EIIFGFKFPPEDK 745
I+FG +F +D+
Sbjct: 181 SIVFGKRFHYQDQ 193
>DQ298753-1|ABB84469.1| 491|Homo sapiens cytochrome P450, family 2,
subfamily B, polypeptide 6 protein.
Length = 491
Score = 85.0 bits (201), Expect = 3e-16
Identities = 52/193 (26%), Positives = 94/193 (48%), Gaps = 2/193 (1%)
Frame = +2
Query: 173 LYFIWLVTFVAGFWIFKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAI 352
L F+ L+T + + + LPPGP LP++G L +DR + + YG +
Sbjct: 6 LLFLALLTGLLLLLVQRHPNTHDRLPPGPRPLPLLGNLLQMDRRGLLKSFLRFREKYGDV 65
Query: 353 YGLKMGSIYAVVLSDHKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQR 526
+ + +G V+L + +R+A ++FSGR + + G G+I A G W+ R
Sbjct: 66 FTVHLGPRPVVMLCGVEAIREALVDKAEAFSGRGKIAMVDPFFRGYGVIFANGNRWKVLR 125
Query: 527 KLITSWLKSFGMSKHSVSREKLEKRIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVN 706
+ + ++ FGM K SV E+RI ++E + K+ A +D + + N++
Sbjct: 126 RFSVTTMRDFGMGKRSV-----EERIQEEAQCLIEELRKSKGALMDPTFLFQSITANIIC 180
Query: 707 EIIFGFKFPPEDK 745
I+FG +F +D+
Sbjct: 181 SIVFGKRFHYQDQ 193
>BC067431-1|AAH67431.1| 491|Homo sapiens cytochrome P450, family 2,
subfamily B, polypeptide 6 protein.
Length = 491
Score = 85.0 bits (201), Expect = 3e-16
Identities = 52/193 (26%), Positives = 94/193 (48%), Gaps = 2/193 (1%)
Frame = +2
Query: 173 LYFIWLVTFVAGFWIFKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAI 352
L F+ L+T + + + LPPGP LP++G L +DR + + YG +
Sbjct: 6 LLFLALLTGLLLLLVQRHPNTHDRLPPGPRPLPLLGNLLQMDRRGLLKSFLRFREKYGDV 65
Query: 353 YGLKMGSIYAVVLSDHKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQR 526
+ + +G V+L + +R+A ++FSGR + + G G+I A G W+ R
Sbjct: 66 FTVHLGPRPVVMLCGVEAIREALVDKAEAFSGRGKIAMVDPFFRGYGVIFANGNRWKVLR 125
Query: 527 KLITSWLKSFGMSKHSVSREKLEKRIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVN 706
+ + ++ FGM K SV E+RI ++E + K+ A +D + + N++
Sbjct: 126 RFSVTTMRDFGMGKRSV-----EERIQEEAQCLIEELRKSKGALMDPTFLFQSITANIIC 180
Query: 707 EIIFGFKFPPEDK 745
I+FG +F +D+
Sbjct: 181 SIVFGKRFHYQDQ 193
>AC023172-1|AAF32444.1| 491|Homo sapiens CYP2B6 protein.
Length = 491
Score = 85.0 bits (201), Expect = 3e-16
Identities = 52/193 (26%), Positives = 94/193 (48%), Gaps = 2/193 (1%)
Frame = +2
Query: 173 LYFIWLVTFVAGFWIFKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAI 352
L F+ L+T + + + LPPGP LP++G L +DR + + YG +
Sbjct: 6 LLFLALLTGLLLLLVQRHPNTHDRLPPGPRPLPLLGNLLQMDRRGLLKSFLRFREKYGDV 65
Query: 353 YGLKMGSIYAVVLSDHKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQR 526
+ + +G V+L + +R+A ++FSGR + + G G+I A G W+ R
Sbjct: 66 FTVHLGPRPVVMLCGVEAIREALVDKAEAFSGRGKIAMVDPFFRGYGVIFANGNRWKVLR 125
Query: 527 KLITSWLKSFGMSKHSVSREKLEKRIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVN 706
+ + ++ FGM K SV E+RI ++E + K+ A +D + + N++
Sbjct: 126 RFSVTTMRDFGMGKRSV-----EERIQEEAQCLIEELRKSKGALMDPTFLFQSITANIIC 180
Query: 707 EIIFGFKFPPEDK 745
I+FG +F +D+
Sbjct: 181 SIVFGKRFHYQDQ 193
>BC067430-1|AAH67430.1| 491|Homo sapiens cytochrome P450, family 2,
subfamily B, polypeptide 6 protein.
Length = 491
Score = 84.6 bits (200), Expect = 4e-16
Identities = 52/193 (26%), Positives = 94/193 (48%), Gaps = 2/193 (1%)
Frame = +2
Query: 173 LYFIWLVTFVAGFWIFKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAI 352
L F+ L+T + + + LPPGP LP++G L +DR + + YG +
Sbjct: 6 LLFLALLTGLLLLLVQRHPNTHDRLPPGPRPLPLLGNLLQMDRRGLLKSFLRFREKYGDV 65
Query: 353 YGLKMGSIYAVVLSDHKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQR 526
+ + +G V+L + +R+A ++FSGR + + G G+I A G W+ R
Sbjct: 66 FTVHLGPRPVVMLCGVEAIREALVDKAEAFSGRGKIAMVDPFFRGYGVIFANGNRWKVLR 125
Query: 527 KLITSWLKSFGMSKHSVSREKLEKRIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVN 706
+ + ++ FGM K SV E+RI ++E + K+ A +D + + N++
Sbjct: 126 RFSVTTMRDFGMGKRSV-----EERIQEEAQCLIEELRKSKGALMDPTFLFHSITANIIC 180
Query: 707 EIIFGFKFPPEDK 745
I+FG +F +D+
Sbjct: 181 SIVFGKRFHYQDQ 193
>AY513608-1|AAR90939.1| 494|Homo sapiens cytochrome P450 2A13
variant 5 protein.
Length = 494
Score = 83.4 bits (197), Expect = 8e-16
Identities = 50/179 (27%), Positives = 88/179 (49%), Gaps = 2/179 (1%)
Frame = +2
Query: 215 IFKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLS 394
++++ K LPPGP LP +G ++ + +L +S+ YG ++ + +G VVL
Sbjct: 23 VWRQRKSRGKLPPGPTPLPFIGNYLQLNTEQMYNSLMKISERYGPVFTIHLGPRRVVVLC 82
Query: 395 DHKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSK 568
H V++A + FSGR L G G+ + G + R+ + L+ FG+ K
Sbjct: 83 GHDAVKEALVDQAEEFSGRGEQATFDWLFKGYGVAFSNGERAKQLRRFSIATLRGFGVGK 142
Query: 569 HSVSREKLEKRIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGFKFPPEDK 745
+ E+RI ++E + T A +D L+ ++ NV++ I+FG +F EDK
Sbjct: 143 RGI-----EERIQEEAGFLIEALRGTHGANIDPTFFLSRTVSNVISSIVFGDRFDYEDK 196
>AF182277-1|AAF13602.1| 491|Homo sapiens cytochrome P450-2B6
protein.
Length = 491
Score = 83.4 bits (197), Expect = 8e-16
Identities = 51/193 (26%), Positives = 93/193 (48%), Gaps = 2/193 (1%)
Frame = +2
Query: 173 LYFIWLVTFVAGFWIFKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAI 352
L F+ L+T + + + LPPGP LP++G L +DR + + YG +
Sbjct: 6 LLFLALLTGLLLLLVQRHPNTHDRLPPGPRPLPLLGNLLQMDRRGLLKSFLRFREKYGDV 65
Query: 353 YGLKMGSIYAVVLSDHKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQR 526
+ + +G V+L + +R+A ++FSGR + + G G+I A G W+ R
Sbjct: 66 FTVHLGPRPVVMLCGVEAIREALVDKAEAFSGRGKIAMVDPFFRGYGVIFANGNRWKVLR 125
Query: 527 KLITSWLKSFGMSKHSVSREKLEKRIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVN 706
+ + ++ FGM K SV E+R ++E + K+ A +D + + N++
Sbjct: 126 RFSVTTMRDFGMGKRSV-----EERTQEEAQCLIEELRKSKGALMDATFLFHSITANIIC 180
Query: 707 EIIFGFKFPPEDK 745
I+FG +F +D+
Sbjct: 181 SIVFGKRFHYQDQ 193
>S46963-1|AAB23864.2| 477|Homo sapiens cytochrome P-450 protein.
Length = 477
Score = 83.0 bits (196), Expect = 1e-15
Identities = 55/169 (32%), Positives = 85/169 (50%), Gaps = 2/169 (1%)
Frame = +2
Query: 245 LPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFS 424
LPPGP LP++G + I +LTNLSK YG ++ L G VVL ++ V++A
Sbjct: 16 LPPGPTPLPVIGNILQIGIKDISKSLTNLSKVYGPVFTLYFGLKPIVVLHGYEAVKEALI 75
Query: 425 K--DSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSKHSVSREKLEK 598
+ FSGR L G GI+ + G W++ R+ L++FGM K S+ E
Sbjct: 76 DLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIRRFSLMTLRNFGMGKRSI-----ED 130
Query: 599 RIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGFKFPPEDK 745
R+ ++E + KT + D +L + NV+ IIF +F +D+
Sbjct: 131 RVQEEARCLVEELRKTKASPCDPTFILGCAPCNVICSIIFHKRFDYKDQ 179
>M29873-1|AAA52143.1| 377|Homo sapiens CYP2B protein.
Length = 377
Score = 83.0 bits (196), Expect = 1e-15
Identities = 52/193 (26%), Positives = 96/193 (49%), Gaps = 2/193 (1%)
Frame = +2
Query: 173 LYFIWLVTFVAGFWIFKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAI 352
L F+ L+T + + + LPPGP LP++G L +DR + + YG +
Sbjct: 6 LLFLALLTGLLLLLVQRHPNSHGTLPPGPRPLPLLGNLLQMDRRGLLKSFLRFREKYGDV 65
Query: 353 YGLKMGSIYAVVLSDHKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQR 526
+ + +G V+L + +R+A + ++FSGR + + + G G++ A G W+ R
Sbjct: 66 FTVHLGPRPVVMLCGVEAIREALVDNAEAFSGRGKIVIMDPVYQGYGMLFANGNRWKVLR 125
Query: 527 KLITSWLKSFGMSKHSVSREKLEKRIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVN 706
+ + ++ FGM K SV E+RI ++E + K+ A +D + + N++
Sbjct: 126 RFSVTTMRDFGMGKRSV-----EERIQDEAQCLIEELRKSKGALVDPTFLFHSITANIIC 180
Query: 707 EIIFGFKFPPEDK 745
IIFG +F +D+
Sbjct: 181 SIIFGKRFHYQDQ 193
>M21942-1|AAA52161.1| 462|Homo sapiens CYP2C protein.
Length = 462
Score = 83.0 bits (196), Expect = 1e-15
Identities = 50/171 (29%), Positives = 89/171 (52%), Gaps = 2/171 (1%)
Frame = +2
Query: 245 LPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAF- 421
LPPGP LPI+G + ID + TN SK YG ++ + G VV ++ V++A
Sbjct: 1 LPPGPTPLPIIGNMLQIDVKDICKSFTNFSKVYGPVFTVYFGMNPIVVFHGYEAVKEALI 60
Query: 422 -SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSKHSVSREKLEK 598
+ + FSGR ++ + G GII + G W++ R+ + L++FGM K S+ E
Sbjct: 61 DNGEEFSGRGNSPISQRITKGLGIISSNGKRWKEIRRFSLTTLRNFGMGKRSI-----ED 115
Query: 599 RIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGFKFPPEDKTW 751
R+ + +++ + KT + D +L + NV+ ++F +F +D+ +
Sbjct: 116 RVQEEAHCLVDELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNF 166
>M21939-1|AAA52158.1| 485|Homo sapiens CYP2C protein.
Length = 485
Score = 83.0 bits (196), Expect = 1e-15
Identities = 55/169 (32%), Positives = 85/169 (50%), Gaps = 2/169 (1%)
Frame = +2
Query: 245 LPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFS 424
LPPGP LP++G + I +LTNLSK YG ++ L G VVL ++ V++A
Sbjct: 24 LPPGPTPLPVIGNILQIGIKDISKSLTNLSKVYGPVFTLYFGLKPIVVLHGYEAVKEALI 83
Query: 425 K--DSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSKHSVSREKLEK 598
+ FSGR L G GI+ + G W++ R+ L++FGM K S+ E
Sbjct: 84 DLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIRRFSLMTLRNFGMGKRSI-----ED 138
Query: 599 RIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGFKFPPEDK 745
R+ ++E + KT + D +L + NV+ IIF +F +D+
Sbjct: 139 RVQEEARCLVEELRKTKASPCDPTFILGCAPCNVICSIIFHKRFDYKDQ 187
>M15331-1|AAA52157.1| 485|Homo sapiens CYP2C protein.
Length = 485
Score = 83.0 bits (196), Expect = 1e-15
Identities = 55/169 (32%), Positives = 85/169 (50%), Gaps = 2/169 (1%)
Frame = +2
Query: 245 LPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFS 424
LPPGP LP++G + I +LTNLSK YG ++ L G VVL ++ V++A
Sbjct: 24 LPPGPTPLPVIGNILQIGIKDISKSLTNLSKVYGPVFTLYFGLKPIVVLHGYEAVKEALI 83
Query: 425 K--DSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSKHSVSREKLEK 598
+ FSGR L G GI+ + G W++ R+ L++FGM K S+ E
Sbjct: 84 DLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIRRFSLMTLRNFGMGKRSI-----ED 138
Query: 599 RIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGFKFPPEDK 745
R+ ++E + KT + D +L + NV+ IIF +F +D+
Sbjct: 139 RVQEEARCLVEELRKTKASPCDPTFILGCAPCNVICSIIFHKRFDYKDQ 187
>L16880-1|AAD13466.1| 273|Homo sapiens cytochrome P-450 2C protein.
Length = 273
Score = 83.0 bits (196), Expect = 1e-15
Identities = 55/169 (32%), Positives = 85/169 (50%), Gaps = 2/169 (1%)
Frame = +2
Query: 245 LPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFS 424
LPPGP LP++G + I +LTNLSK YG ++ L G VVL ++ V++A
Sbjct: 29 LPPGPTPLPVIGNILQIGIKDISKSLTNLSKVYGPVFTLYFGLKPIVVLHGYEAVKEALI 88
Query: 425 K--DSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSKHSVSREKLEK 598
+ FSGR L G GI+ + G W++ R+ L++FGM K S+ E
Sbjct: 89 DLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIRRFSLMTLRNFGMGKRSI-----ED 143
Query: 599 RIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGFKFPPEDK 745
R+ ++E + KT + D +L + NV+ IIF +F +D+
Sbjct: 144 RVQEEARCLVEELRKTKASPCDPTFILGCAPCNVICSIIFHKRFDYKDQ 192
>D00173-1|BAA00123.1| 487|Homo sapiens cytochrome P-450 protein.
Length = 487
Score = 83.0 bits (196), Expect = 1e-15
Identities = 55/169 (32%), Positives = 85/169 (50%), Gaps = 2/169 (1%)
Frame = +2
Query: 245 LPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFS 424
LPPGP LP++G + I +LTNLSK YG ++ L G VVL ++ V++A
Sbjct: 26 LPPGPTPLPVIGNILQIGIKDISKSLTNLSKVYGPVFTLYFGLKPIVVLHGYEAVKEALI 85
Query: 425 K--DSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSKHSVSREKLEK 598
+ FSGR L G GI+ + G W++ R+ L++FGM K S+ E
Sbjct: 86 DLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIRRFSLMTLRNFGMGKRSI-----ED 140
Query: 599 RIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGFKFPPEDK 745
R+ ++E + KT + D +L + NV+ IIF +F +D+
Sbjct: 141 RVQEEARCLVEELRKTKASPCDPTFILGCAPCNVICSIIFHKRFDYKDQ 189
>BC125054-1|AAI25055.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 9 protein.
Length = 490
Score = 83.0 bits (196), Expect = 1e-15
Identities = 55/169 (32%), Positives = 85/169 (50%), Gaps = 2/169 (1%)
Frame = +2
Query: 245 LPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFS 424
LPPGP LP++G + I +LTNLSK YG ++ L G VVL ++ V++A
Sbjct: 29 LPPGPTPLPVIGNILQIGIKDISKSLTNLSKVYGPVFTLYFGLKPIVVLHGYEAVKEALI 88
Query: 425 K--DSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSKHSVSREKLEK 598
+ FSGR L G GI+ + G W++ R+ L++FGM K S+ E
Sbjct: 89 DLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIRRFSLMTLRNFGMGKRSI-----ED 143
Query: 599 RIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGFKFPPEDK 745
R+ ++E + KT + D +L + NV+ IIF +F +D+
Sbjct: 144 RVQEEARCLVEELRKTKASPCDPTFILGCAPCNVICSIIFHKRFDYKDQ 192
>BC041174-1|AAH41174.1| 377|Homo sapiens CYP2B7P1 protein protein.
Length = 377
Score = 83.0 bits (196), Expect = 1e-15
Identities = 52/193 (26%), Positives = 96/193 (49%), Gaps = 2/193 (1%)
Frame = +2
Query: 173 LYFIWLVTFVAGFWIFKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAI 352
L F+ L+T + + + LPPGP LP++G L +DR + + YG +
Sbjct: 6 LLFLALLTGLLLLLVQRHPNSHGTLPPGPRPLPLLGNLLQMDRRGLLKSFLRFREKYGDV 65
Query: 353 YGLKMGSIYAVVLSDHKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQR 526
+ + +G V+L + +R+A + ++FSGR + + + G G++ A G W+ R
Sbjct: 66 FTVHLGPRPVVMLCGVEAIREALVDNAEAFSGRGKIVIMDPVYQGYGMLFANGNRWKVLR 125
Query: 527 KLITSWLKSFGMSKHSVSREKLEKRIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVN 706
+ + ++ FGM K SV E+RI ++E + K+ A +D + + N++
Sbjct: 126 RFSVTTMRDFGMGKRSV-----EERIQDEAQCLIEELRKSKGALVDPTFLFHSITANIIC 180
Query: 707 EIIFGFKFPPEDK 745
IIFG +F +D+
Sbjct: 181 SIIFGKRFHYQDQ 193
>AY702706-1|AAT94065.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 9 protein.
Length = 490
Score = 83.0 bits (196), Expect = 1e-15
Identities = 55/169 (32%), Positives = 85/169 (50%), Gaps = 2/169 (1%)
Frame = +2
Query: 245 LPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFS 424
LPPGP LP++G + I +LTNLSK YG ++ L G VVL ++ V++A
Sbjct: 29 LPPGPTPLPVIGNILQIGIKDISKSLTNLSKVYGPVFTLYFGLKPIVVLHGYEAVKEALI 88
Query: 425 K--DSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSKHSVSREKLEK 598
+ FSGR L G GI+ + G W++ R+ L++FGM K S+ E
Sbjct: 89 DLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIRRFSLMTLRNFGMGKRSI-----ED 143
Query: 599 RIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGFKFPPEDK 745
R+ ++E + KT + D +L + NV+ IIF +F +D+
Sbjct: 144 RVQEEARCLVEELRKTKASPCDPTFILGCAPCNVICSIIFHKRFDYKDQ 192
>AY341248-1|AAP88931.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 9 protein.
Length = 490
Score = 83.0 bits (196), Expect = 1e-15
Identities = 55/169 (32%), Positives = 85/169 (50%), Gaps = 2/169 (1%)
Frame = +2
Query: 245 LPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFS 424
LPPGP LP++G + I +LTNLSK YG ++ L G VVL ++ V++A
Sbjct: 29 LPPGPTPLPVIGNILQIGIKDISKSLTNLSKVYGPVFTLYFGLKPIVVLHGYEAVKEALI 88
Query: 425 K--DSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSKHSVSREKLEK 598
+ FSGR L G GI+ + G W++ R+ L++FGM K S+ E
Sbjct: 89 DLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIRRFSLMTLRNFGMGKRSI-----ED 143
Query: 599 RIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGFKFPPEDK 745
R+ ++E + KT + D +L + NV+ IIF +F +D+
Sbjct: 144 RVQEEARCLVEELRKTKASPCDPTFILGCAPCNVICSIIFHKRFDYKDQ 192
>AL359672-1|CAH71303.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 9 protein.
Length = 490
Score = 83.0 bits (196), Expect = 1e-15
Identities = 55/169 (32%), Positives = 85/169 (50%), Gaps = 2/169 (1%)
Frame = +2
Query: 245 LPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFS 424
LPPGP LP++G + I +LTNLSK YG ++ L G VVL ++ V++A
Sbjct: 29 LPPGPTPLPVIGNILQIGIKDISKSLTNLSKVYGPVFTLYFGLKPIVVLHGYEAVKEALI 88
Query: 425 K--DSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSKHSVSREKLEK 598
+ FSGR L G GI+ + G W++ R+ L++FGM K S+ E
Sbjct: 89 DLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIRRFSLMTLRNFGMGKRSI-----ED 143
Query: 599 RIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGFKFPPEDK 745
R+ ++E + KT + D +L + NV+ IIF +F +D+
Sbjct: 144 RVQEEARCLVEELRKTKASPCDPTFILGCAPCNVICSIIFHKRFDYKDQ 192
>AF084225-1|AAD13753.1| 462|Homo sapiens cytochrome P450 2E1
protein.
Length = 462
Score = 83.0 bits (196), Expect = 1e-15
Identities = 56/185 (30%), Positives = 92/185 (49%), Gaps = 2/185 (1%)
Frame = +2
Query: 245 LPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAF- 421
LPPGP+ LPI+G L ++ + + T L++ +G ++ L +GS VV+ +K V++A
Sbjct: 1 LPPGPFPLPIIGNLFQLELKNIPKSFTRLAQRFGPVFTLYVGSQRMVVMHGYKAVKEALL 60
Query: 422 -SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSKHSVSREKLEK 598
KD FSGR L H GII G W+D R+ + L+++GM K + E
Sbjct: 61 DYKDEFSGRGDLPAFHA-HRDRGIIFNNGPTWKDIRRFSLTTLRNYGMGK-----QGNES 114
Query: 599 RIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGFKFPPEDKTWQWFRQIQEE 778
RI + +LE + KT D ++ + NV+ +I+F F D+ + + E
Sbjct: 115 RIQREAHFLLEALRKTQGQPFDPTFLIGCAPCNVIADILFRKHFDYNDEKFLRLMYLFNE 174
Query: 779 GCHXM 793
H +
Sbjct: 175 NFHLL 179
>BC033691-1|AAH33691.1| 504|Homo sapiens cytochrome P450, family 2,
subfamily S, polypeptide 1 protein.
Length = 504
Score = 82.6 bits (195), Expect = 1e-15
Identities = 56/174 (32%), Positives = 86/174 (49%), Gaps = 3/174 (1%)
Frame = +2
Query: 242 NLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIY-AVVLSDHKLVRDA 418
+LPPGP LP++G L + + L LSK YG ++ + +G VVL + VR+A
Sbjct: 31 HLPPGPTPLPLLGNLLQLRPGALYSGLMRLSKKYGPVFTIYLGPWRPVVVLVGQEAVREA 90
Query: 419 FS--KDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSKHSVSREKL 592
+ FSGR + + G +G+G+ + G WR RK L+ GM K RE
Sbjct: 91 LGGQAEEFSGRGTVAMLEGTFDGHGVFFSNGERWRQLRKFTMLALRDLGMGK----REG- 145
Query: 593 EKRIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGFKFPPEDKTWQ 754
E+ I + ++E + T D +L + NVV ++FG +F EDK +Q
Sbjct: 146 EELIQAEARCLVETFQGTEGRPFDPSLLLAQATSNVVCSLLFGLRFSYEDKEFQ 199
>AY358603-1|AAQ88966.1| 504|Homo sapiens Cytochrome p450 protein.
Length = 504
Score = 82.6 bits (195), Expect = 1e-15
Identities = 56/174 (32%), Positives = 86/174 (49%), Gaps = 3/174 (1%)
Frame = +2
Query: 242 NLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIY-AVVLSDHKLVRDA 418
+LPPGP LP++G L + + L LSK YG ++ + +G VVL + VR+A
Sbjct: 31 HLPPGPTPLPLLGNLLQLRPGALYSGLMRLSKKYGPVFTIYLGPWRPVVVLVGQEAVREA 90
Query: 419 FS--KDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSKHSVSREKL 592
+ FSGR + + G +G+G+ + G WR RK L+ GM K RE
Sbjct: 91 LGGQAEEFSGRGTVAMLEGTFDGHGVFFSNGERWRQLRKFTMLALRDLGMGK----REG- 145
Query: 593 EKRIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGFKFPPEDKTWQ 754
E+ I + ++E + T D +L + NVV ++FG +F EDK +Q
Sbjct: 146 EELIQAEARCLVETFQGTEGRPFDPSLLLAQATSNVVCSLLFGLRFSYEDKEFQ 199
>AK027605-1|BAB55227.1| 564|Homo sapiens protein ( Homo sapiens
cDNA FLJ14699 fis, clone NT2RP2006571, moderately
similar to CYTOCHROME P450 2G1 (EC 1.14.14.1). ).
Length = 564
Score = 82.6 bits (195), Expect = 1e-15
Identities = 56/174 (32%), Positives = 86/174 (49%), Gaps = 3/174 (1%)
Frame = +2
Query: 242 NLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIY-AVVLSDHKLVRDA 418
+LPPGP LP++G L + + L LSK YG ++ + +G VVL + VR+A
Sbjct: 31 HLPPGPTPLPLLGNLLQLRPGALYSGLMRLSKKYGPVFTIYLGPWRPVVVLVGQEAVREA 90
Query: 419 FS--KDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSKHSVSREKL 592
+ FSGR + + G +G+G+ + G WR RK L+ GM K RE
Sbjct: 91 LGGQAEEFSGRGTVAMLEGTFDGHGVFFSNGERWRQLRKFTMLALRDLGMGK----REG- 145
Query: 593 EKRIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGFKFPPEDKTWQ 754
E+ I + ++E + T D +L + NVV ++FG +F EDK +Q
Sbjct: 146 EELIQAEARCLVETFQGTEGRPFDPSLLLAQATSNVVCSLLFGLRFSYEDKEFQ 199
>AF335278-1|AAK13498.1| 504|Homo sapiens cytochrome P450 2S1
protein.
Length = 504
Score = 82.6 bits (195), Expect = 1e-15
Identities = 56/174 (32%), Positives = 86/174 (49%), Gaps = 3/174 (1%)
Frame = +2
Query: 242 NLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIY-AVVLSDHKLVRDA 418
+LPPGP LP++G L + + L LSK YG ++ + +G VVL + VR+A
Sbjct: 31 HLPPGPTPLPLLGNLLQLRPGALYSGLMRLSKKYGPVFTIYLGPWRPVVVLVGQEAVREA 90
Query: 419 FS--KDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSKHSVSREKL 592
+ FSGR + + G +G+G+ + G WR RK L+ GM K RE
Sbjct: 91 LGGQAEEFSGRGTVAMLEGTFDGHGVFFSNGERWRQLRKFTMLALRDLGMGK----REG- 145
Query: 593 EKRIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGFKFPPEDKTWQ 754
E+ I + ++E + T D +L + NVV ++FG +F EDK +Q
Sbjct: 146 EELIQAEARCLVETFQGTEGRPFDPSLLLAQATSNVVCSLLFGLRFSYEDKEFQ 199
>X13897-1|CAA32097.1| 489|Homo sapiens protein ( Human mRNA for
cytochrome P-450IIA. ).
Length = 489
Score = 82.2 bits (194), Expect = 2e-15
Identities = 48/179 (26%), Positives = 89/179 (49%), Gaps = 2/179 (1%)
Frame = +2
Query: 215 IFKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLS 394
++++ K LPPGP LP +G ++ + +L +S+ YG ++ + +G VVL
Sbjct: 18 VWQQRKNKGKLPPGPTPLPFIGNYLQLNTEQMYNSLMKISERYGPVFTIHLGPRRVVVLC 77
Query: 395 DHKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSK 568
H VR+A + FSGR + G G++ + G + R+ + L+ FG+ K
Sbjct: 78 GHDAVREALVDQAEEFSGRGEQATFDWVFKGYGVVFSNGERAKQLRRFSIATLRDFGVGK 137
Query: 569 HSVSREKLEKRIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGFKFPPEDK 745
+ E+RI +++ + T A +D L+ ++ NV++ I+FG +F +DK
Sbjct: 138 RGI-----EERIQEEAGFLIDALRGTGGANIDPTFFLSRTVSNVISSIVFGDRFDYKDK 191
>U22028-1|AAB40519.1| 494|Homo sapiens cytochrome P450 protein.
Length = 494
Score = 82.2 bits (194), Expect = 2e-15
Identities = 49/179 (27%), Positives = 88/179 (49%), Gaps = 2/179 (1%)
Frame = +2
Query: 215 IFKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLS 394
++++ K LPPGP LP +G ++ + +L +S+ YG ++ + +G VVL
Sbjct: 23 VWRQRKSRGKLPPGPTPLPFIGNYLQLNTEQMYNSLMKISERYGPVFTIHLGPRRVVVLC 82
Query: 395 DHKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSK 568
H V++A + FSGR L G G+ + G + R+ + L+ FG+ K
Sbjct: 83 GHDAVKEALVDQAEEFSGRGEQATFDWLFKGYGVAFSNGERAKQLRRFSIATLRGFGVGK 142
Query: 569 HSVSREKLEKRIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGFKFPPEDK 745
+ E+RI +++ + T A +D L+ ++ NV++ I+FG +F EDK
Sbjct: 143 RGI-----EERIQEEAGFLIDALRGTHGANIDPTFFLSRTVSNVISSIVFGDRFDYEDK 196
>M33318-1|AAA52067.1| 494|Homo sapiens CYP2A protein.
Length = 494
Score = 82.2 bits (194), Expect = 2e-15
Identities = 48/179 (26%), Positives = 89/179 (49%), Gaps = 2/179 (1%)
Frame = +2
Query: 215 IFKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLS 394
++++ K LPPGP LP +G ++ + +L +S+ YG ++ + +G VVL
Sbjct: 23 VWQQRKSKGKLPPGPTPLPFIGNYLQLNTEQMYNSLMKISERYGPVFTIHLGPRRVVVLC 82
Query: 395 DHKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSK 568
H VR+A + FSGR + G G++ + G + R+ + L+ FG+ K
Sbjct: 83 GHDAVREALVDQAEEFSGRGEQATFDWVFKGYGVVFSNGERAKQLRRFSIATLRDFGVGK 142
Query: 569 HSVSREKLEKRIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGFKFPPEDK 745
+ E+RI +++ + T A +D L+ ++ NV++ I+FG +F +DK
Sbjct: 143 RGI-----EERIQEEAGFLIDALRGTGGANIDPTFFLSRTVSNVISSIVFGDRFDYKDK 196
>BC117165-1|AAI17166.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 7 protein.
Length = 494
Score = 82.2 bits (194), Expect = 2e-15
Identities = 51/179 (28%), Positives = 87/179 (48%), Gaps = 2/179 (1%)
Frame = +2
Query: 215 IFKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLS 394
++++ K LPPGP LP +G ++ H ++ S+ YG ++ + +G AVVL
Sbjct: 23 VWQQRKSRGKLPPGPTPLPFIGNYLQLNTEHICDSIMKFSECYGPVFTIHLGPRRAVVLC 82
Query: 395 DHKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSK 568
H VR+A + FSGR + G G+ + G + + + L+ FG+ K
Sbjct: 83 GHDAVREALVDQAEEFSGRGEQATFDWVFKGYGVAFSNGERAKQLLRFAIATLRDFGVGK 142
Query: 569 HSVSREKLEKRIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGFKFPPEDK 745
+ E+RI ++E I T A +D L+ ++ NV++ I+FG +F EDK
Sbjct: 143 RGI-----EERIQEESGFLIEAIRSTHGANIDPTFFLSRTVSNVISSIVFGDRFDYEDK 196
>BC104909-1|AAI04910.1| 501|Homo sapiens cytochrome P450, family 2,
subfamily R, polypeptide 1 protein.
Length = 501
Score = 82.2 bits (194), Expect = 2e-15
Identities = 58/204 (28%), Positives = 93/204 (45%), Gaps = 5/204 (2%)
Frame = +2
Query: 182 IWLVTFVAGFWIFKKIKEWQNLPPGPWGLPIVG--YLPFIDRYHPHITLTNLSKTYGAIY 355
++L+ F G K + PPGP GLP +G Y PH+ + S+ YG I+
Sbjct: 18 LFLLLFALGVRQLLKQRRPMGFPPGPPGLPFIGNIYSLAASSELPHVYMRKQSQVYGEIF 77
Query: 356 GLKMGSIYAVVLSDHKLVRDAFSKDS--FSGRAPLYLTHGLMNGNGIICAEGGL-WRDQR 526
L +G I VVL+ + +V++ S F+ R L L + G++ + G W D R
Sbjct: 78 SLDLGGISTVVLNGYDVVKECLVHQSEIFADRPCLPLFMKMTKMGGLLNSRYGRGWVDHR 137
Query: 527 KLITSWLKSFGMSKHSVSREKLEKRIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVN 706
+L + + FG + S E +I + IE D ++TN++ N+ N
Sbjct: 138 RLAVNSFRYFGYGQKS-----FESKILEETKFFNDAIETYKGRPFDFKQLITNAVSNITN 192
Query: 707 EIIFGFKFPPEDKTWQWFRQIQEE 778
IIFG +F ED +Q ++ E
Sbjct: 193 LIIFGERFTYEDTDFQHMIELFSE 216
>BC104907-1|AAI04908.1| 501|Homo sapiens cytochrome P450, family 2,
subfamily R, polypeptide 1 protein.
Length = 501
Score = 82.2 bits (194), Expect = 2e-15
Identities = 58/204 (28%), Positives = 93/204 (45%), Gaps = 5/204 (2%)
Frame = +2
Query: 182 IWLVTFVAGFWIFKKIKEWQNLPPGPWGLPIVG--YLPFIDRYHPHITLTNLSKTYGAIY 355
++L+ F G K + PPGP GLP +G Y PH+ + S+ YG I+
Sbjct: 18 LFLLLFALGVRQLLKQRRPMGFPPGPPGLPFIGNIYSLAASSELPHVYMRKQSQVYGEIF 77
Query: 356 GLKMGSIYAVVLSDHKLVRDAFSKDS--FSGRAPLYLTHGLMNGNGIICAEGGL-WRDQR 526
L +G I VVL+ + +V++ S F+ R L L + G++ + G W D R
Sbjct: 78 SLDLGGISTVVLNGYDVVKECLVHQSEIFADRPCLPLFMKMTKMGGLLNSRYGRGWVDHR 137
Query: 527 KLITSWLKSFGMSKHSVSREKLEKRIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVN 706
+L + + FG + S E +I + IE D ++TN++ N+ N
Sbjct: 138 RLAVNSFRYFGYGQKS-----FESKILEETKFFNDAIETYKGRPFDFKQLITNAVSNITN 192
Query: 707 EIIFGFKFPPEDKTWQWFRQIQEE 778
IIFG +F ED +Q ++ E
Sbjct: 193 LIIFGERFTYEDTDFQHMIELFSE 216
>BC096256-1|AAH96256.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 82.2 bits (194), Expect = 2e-15
Identities = 48/179 (26%), Positives = 89/179 (49%), Gaps = 2/179 (1%)
Frame = +2
Query: 215 IFKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLS 394
++++ K LPPGP LP +G ++ + +L +S+ YG ++ + +G VVL
Sbjct: 23 VWQQRKSKGKLPPGPTPLPFIGNYLQLNTEQMYNSLMKISERYGPVFTIHLGPRRVVVLC 82
Query: 395 DHKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSK 568
H VR+A + FSGR + G G++ + G + R+ + L+ FG+ K
Sbjct: 83 GHDAVREALVDQAEEFSGRGEQATFDWVFKGYGVVFSNGERAKQLRRFSIATLRDFGVGK 142
Query: 569 HSVSREKLEKRIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGFKFPPEDK 745
+ E+RI +++ + T A +D L+ ++ NV++ I+FG +F +DK
Sbjct: 143 RGI-----EERIQEEAGFLIDALRGTGGANIDPTFFLSRTVSNVISSIVFGDRFDYKDK 196
>BC096254-1|AAH96254.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 82.2 bits (194), Expect = 2e-15
Identities = 48/179 (26%), Positives = 89/179 (49%), Gaps = 2/179 (1%)
Frame = +2
Query: 215 IFKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLS 394
++++ K LPPGP LP +G ++ + +L +S+ YG ++ + +G VVL
Sbjct: 23 VWQQRKSKGKLPPGPTPLPFIGNYLQLNTEQMYNSLMKISERYGPVFTIHLGPRRVVVLC 82
Query: 395 DHKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSK 568
H VR+A + FSGR + G G++ + G + R+ + L+ FG+ K
Sbjct: 83 GHDAVREALVDQAEEFSGRGEQATFDWVFKGYGVVFSNGERAKQLRRFSIATLRDFGVGK 142
Query: 569 HSVSREKLEKRIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGFKFPPEDK 745
+ E+RI +++ + T A +D L+ ++ NV++ I+FG +F +DK
Sbjct: 143 RGI-----EERIQEEAGFLIDALRGTGGANIDPTFFLSRTVSNVISSIVFGDRFDYKDK 196
>BC096253-1|AAH96253.3| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 82.2 bits (194), Expect = 2e-15
Identities = 48/179 (26%), Positives = 89/179 (49%), Gaps = 2/179 (1%)
Frame = +2
Query: 215 IFKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLS 394
++++ K LPPGP LP +G ++ + +L +S+ YG ++ + +G VVL
Sbjct: 23 VWQQRKSKGKLPPGPTPLPFIGNYLQLNTEQMYNSLMKISERYGPVFTIHLGPRRVVVLC 82
Query: 395 DHKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSK 568
H VR+A + FSGR + G G++ + G + R+ + L+ FG+ K
Sbjct: 83 GHDAVREALVDQAEEFSGRGEQATFDWVFKGYGVVFSNGERAKQLRRFSIATLRDFGVGK 142
Query: 569 HSVSREKLEKRIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGFKFPPEDK 745
+ E+RI +++ + T A +D L+ ++ NV++ I+FG +F +DK
Sbjct: 143 RGI-----EERIQEEAGFLIDALRGTGGANIDPTFFLSRTVSNVISSIVFGDRFDYKDK 196
>AY513609-1|AAR90940.1| 494|Homo sapiens cytochrome P450 2A13
variant 6 protein.
Length = 494
Score = 82.2 bits (194), Expect = 2e-15
Identities = 49/179 (27%), Positives = 88/179 (49%), Gaps = 2/179 (1%)
Frame = +2
Query: 215 IFKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLS 394
++++ K LPPGP LP +G ++ + +L +S+ YG ++ + +G VVL
Sbjct: 23 VWRQRKSRGKLPPGPTPLPFIGNYLQLNTEQMYNSLMKISERYGPVFTIHLGPRRVVVLC 82
Query: 395 DHKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSK 568
H V++A + FSGR L G G+ + G + R+ + L+ FG+ K
Sbjct: 83 GHDAVKEALVDQAEEFSGRGEQATFDWLFKGYGVAFSNGERAKQLRRFSIATLRGFGVGK 142
Query: 569 HSVSREKLEKRIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGFKFPPEDK 745
+ E+RI +++ + T A +D L+ ++ NV++ I+FG +F EDK
Sbjct: 143 RGI-----EERIQEEAGFLIDALRGTHGANIDPTFFLSRTVSNVISSIVFGDRFDYEDK 196
>AY513606-1|AAR90937.1| 494|Homo sapiens cytochrome P450 2A13
variant 3 protein.
Length = 494
Score = 82.2 bits (194), Expect = 2e-15
Identities = 49/179 (27%), Positives = 88/179 (49%), Gaps = 2/179 (1%)
Frame = +2
Query: 215 IFKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLS 394
++++ K LPPGP LP +G ++ + +L +S+ YG ++ + +G VVL
Sbjct: 23 VWRQRKSRGKLPPGPTPLPFIGNYLQLNTEQMYNSLMKISERYGPVFTIHLGPRRVVVLC 82
Query: 395 DHKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSK 568
H V++A + FSGR L G G+ + G + R+ + L+ FG+ K
Sbjct: 83 GHDAVKEALVDQAEEFSGRGEQATFDWLFKGYGVAFSNGERAKQLRRFSIATLRGFGVGK 142
Query: 569 HSVSREKLEKRIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGFKFPPEDK 745
+ E+RI +++ + T A +D L+ ++ NV++ I+FG +F EDK
Sbjct: 143 RGI-----EERIQEEAGFLIDALRGTHGANIDPTFFLSRTVSNVISSIVFGDRFDYEDK 196
>AY513605-1|AAR90936.1| 494|Homo sapiens cytochrome P450 2A13
variant 2 protein.
Length = 494
Score = 82.2 bits (194), Expect = 2e-15
Identities = 49/179 (27%), Positives = 88/179 (49%), Gaps = 2/179 (1%)
Frame = +2
Query: 215 IFKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLS 394
++++ K LPPGP LP +G ++ + +L +S+ YG ++ + +G VVL
Sbjct: 23 VWRQRKSRGKLPPGPTPLPFIGNYLQLNTEQMYNSLMKISERYGPVFTIHLGPRRVVVLC 82
Query: 395 DHKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSK 568
H V++A + FSGR L G G+ + G + R+ + L+ FG+ K
Sbjct: 83 GHDAVKEALVDQAEEFSGRGEQATFDWLFKGYGVAFSNGERAKQLRRFSIATLRGFGVGK 142
Query: 569 HSVSREKLEKRIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGFKFPPEDK 745
+ E+RI +++ + T A +D L+ ++ NV++ I+FG +F EDK
Sbjct: 143 RGI-----EERIQEEAGFLIDALRGTHGANIDPTFFLSRTVSNVISSIVFGDRFDYEDK 196
>AY513604-1|AAR90935.1| 494|Homo sapiens cytochrome P450 2A13
variant 1 protein.
Length = 494
Score = 82.2 bits (194), Expect = 2e-15
Identities = 49/179 (27%), Positives = 88/179 (49%), Gaps = 2/179 (1%)
Frame = +2
Query: 215 IFKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLS 394
++++ K LPPGP LP +G ++ + +L +S+ YG ++ + +G VVL
Sbjct: 23 VWRQRKSRGKLPPGPTPLPFIGNYLQLNTEQMYNSLMKISERYGPVFTIHLGPRRVVVLC 82
Query: 395 DHKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSK 568
H V++A + FSGR L G G+ + G + R+ + L+ FG+ K
Sbjct: 83 GHDAVKEALVDQAEEFSGRGEQATFDWLFKGYGVAFSNGERAKQLRRFSIATLRGFGVGK 142
Query: 569 HSVSREKLEKRIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGFKFPPEDK 745
+ E+RI +++ + T A +D L+ ++ NV++ I+FG +F EDK
Sbjct: 143 RGI-----EERIQEEAGFLIDALRGTHGANIDPTFFLSRTVSNVISSIVFGDRFDYEDK 196
>AY323817-1|AAQ23114.1| 501|Homo sapiens cytochrome P450 2R1
protein.
Length = 501
Score = 82.2 bits (194), Expect = 2e-15
Identities = 58/204 (28%), Positives = 93/204 (45%), Gaps = 5/204 (2%)
Frame = +2
Query: 182 IWLVTFVAGFWIFKKIKEWQNLPPGPWGLPIVG--YLPFIDRYHPHITLTNLSKTYGAIY 355
++L+ F G K + PPGP GLP +G Y PH+ + S+ YG I+
Sbjct: 18 LFLLLFALGVRQLLKQRRPMGFPPGPPGLPFIGNIYSLAASSELPHVYMRKQSQVYGEIF 77
Query: 356 GLKMGSIYAVVLSDHKLVRDAFSKDS--FSGRAPLYLTHGLMNGNGIICAEGGL-WRDQR 526
L +G I VVL+ + +V++ S F+ R L L + G++ + G W D R
Sbjct: 78 SLDLGGISTVVLNGYDVVKECLVHQSEIFADRPCLPLFMKMTKMGGLLNSRYGRGWVDHR 137
Query: 527 KLITSWLKSFGMSKHSVSREKLEKRIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVN 706
+L + + FG + S E +I + IE D ++TN++ N+ N
Sbjct: 138 RLAVNSFRYFGYGQKS-----FESKILEETKFFNDAIETYKGRPFDFKQLITNAVSNITN 192
Query: 707 EIIFGFKFPPEDKTWQWFRQIQEE 778
IIFG +F ED +Q ++ E
Sbjct: 193 LIIFGERFTYEDTDFQHMIELFSE 216
>AF209774-1|AAG35775.1| 494|Homo sapiens cytochrome P450 2A13
protein.
Length = 494
Score = 82.2 bits (194), Expect = 2e-15
Identities = 49/179 (27%), Positives = 88/179 (49%), Gaps = 2/179 (1%)
Frame = +2
Query: 215 IFKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLS 394
++++ K LPPGP LP +G ++ + +L +S+ YG ++ + +G VVL
Sbjct: 23 VWRQRKSRGKLPPGPTPLPFIGNYLQLNTEQMYNSLMKISERYGPVFTIHLGPRRVVVLC 82
Query: 395 DHKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSK 568
H V++A + FSGR L G G+ + G + R+ + L+ FG+ K
Sbjct: 83 GHDAVKEALVDQAEEFSGRGEQATFDWLFKGYGVAFSNGERAKQLRRFSIATLRGFGVGK 142
Query: 569 HSVSREKLEKRIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGFKFPPEDK 745
+ E+RI +++ + T A +D L+ ++ NV++ I+FG +F EDK
Sbjct: 143 RGI-----EERIQEEAGFLIDALRGTHGANIDPTFFLSRTVSNVISSIVFGDRFDYEDK 196
>AF182275-1|AAF13600.1| 494|Homo sapiens cytochrome P450-2A6
protein.
Length = 494
Score = 82.2 bits (194), Expect = 2e-15
Identities = 48/179 (26%), Positives = 89/179 (49%), Gaps = 2/179 (1%)
Frame = +2
Query: 215 IFKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLS 394
++++ K LPPGP LP +G ++ + +L +S+ YG ++ + +G VVL
Sbjct: 23 VWQQRKSKGKLPPGPTPLPFIGNYLQLNTEQMYNSLMKISERYGPVFTIHLGPRRVVVLC 82
Query: 395 DHKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSK 568
H VR+A + FSGR + G G++ + G + R+ + L+ FG+ K
Sbjct: 83 GHDAVREALVDQAEEFSGRGEQATFDWVFKGYGVVFSNGERAKQLRRFSIATLRDFGVGK 142
Query: 569 HSVSREKLEKRIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGFKFPPEDK 745
+ E+RI +++ + T A +D L+ ++ NV++ I+FG +F +DK
Sbjct: 143 RGI-----EERIQEEAGFLIDALRGTGGANIDPTFFLSRTVSNVISSIVFGDRFDYKDK 196
>U22027-1|AAB40518.1| 494|Homo sapiens cytochrome P450 protein.
Length = 494
Score = 81.4 bits (192), Expect = 3e-15
Identities = 49/179 (27%), Positives = 88/179 (49%), Gaps = 2/179 (1%)
Frame = +2
Query: 215 IFKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLS 394
++++ K LPPGP LP +G ++ + +L +S+ YG ++ + +G VVL
Sbjct: 23 VWQQRKSKGKLPPGPTPLPFIGNYLQLNTEQMYNSLMKISERYGPVFTIHLGPRRVVVLC 82
Query: 395 DHKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSK 568
H VR+A + FSGR + G G++ + G + + + L+ FG+ K
Sbjct: 83 GHDAVREALVDQAEEFSGRGEQATFDWVFKGYGVVFSNGERAKQLLRFAIATLRDFGVGK 142
Query: 569 HSVSREKLEKRIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGFKFPPEDK 745
+ E+RI ++E I T A +D L+ ++ NV++ I+FG +F +DK
Sbjct: 143 RGI-----EERIQEESGFLIEAIRSTHGANIDPTFFLSRTVSNVISSIVFGDRFDYKDK 196
>AY871801-1|AAX62803.1| 483|Homo sapiens cytochrome P450 family 1
subfamily A polypeptide 1 protein.
Length = 483
Score = 81.4 bits (192), Expect = 3e-15
Identities = 52/204 (25%), Positives = 101/204 (49%), Gaps = 12/204 (5%)
Frame = +2
Query: 155 LSSNMDLYFIWLVTFVAGFWIFK----KIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITL 322
+S + + + V F FW+ + ++ + PPGPWG P++G++ + + +PH+ L
Sbjct: 5 ISMSATKFLLASVIFCLVFWVIRASRPQVPKGLENPPGPWGWPLIGHMLTLGK-NPHLAL 63
Query: 323 TNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSK--DSFSGRAPLYLTHGLMNGNGIIC 496
+ +S+ YG + +++GS VVLS +R A + D F GR LY + NG +
Sbjct: 64 SRMSQQYGDVLQIRIGSTPVVVLSGLDTIRQALVRQGDDFKGRPDLYTFTLISNGQSMSF 123
Query: 497 A--EGGLWRDQRKLITSWLKSFGMSKHSVSREK--LEKRIASGVYEILENIEK--TSDAA 658
+ G +W +R+L + LKSF ++ S LE+ ++ ++ +++
Sbjct: 124 SPDSGPVWAARRRLAQNGLKSFSIASDPASSTSCYLEEHVSKEAEVLISTLQELMAGPGH 183
Query: 659 LDLPHMLTNSLGNVVNEIIFGFKF 730
+ + S+ NV+ I FG ++
Sbjct: 184 FNPYRYVVVSVTNVICAICFGRRY 207
>AK223108-1|BAD96828.1| 512|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 1 variant protein.
Length = 512
Score = 81.4 bits (192), Expect = 3e-15
Identities = 52/204 (25%), Positives = 101/204 (49%), Gaps = 12/204 (5%)
Frame = +2
Query: 155 LSSNMDLYFIWLVTFVAGFWIFK----KIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITL 322
+S + + + V F FW+ + ++ + PPGPW P++G++ + + +PH+ L
Sbjct: 5 ISMSATEFLLASVIFCLVFWVIRASRPQVPKGLKNPPGPWDWPLIGHMLTLGK-NPHLAL 63
Query: 323 TNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSK--DSFSGRAPLYLTHGLMNGNGIIC 496
+ +S+ YG + +++GS VVLS +R A + D F GR LY + NG +
Sbjct: 64 SRMSQQYGDVLQIRIGSTPVVVLSGLDTIRQALVRQGDDFKGRPDLYTFTLISNGQSMSF 123
Query: 497 A--EGGLWRDQRKLITSWLKSFGMSKHSVSREK--LEKRIASGVYEILENIEK--TSDAA 658
+ G +W +R+L + LKSF ++ S LE+ ++ G ++ +++
Sbjct: 124 SPDSGPVWAARRRLAQNGLKSFSIASDPASSTSCYLEEHVSKGAEVLISTLQELMAGPGH 183
Query: 659 LDLPHMLTNSLGNVVNEIIFGFKF 730
+ + S+ NV+ I FG ++
Sbjct: 184 FNPYRYVVVSVTNVICAICFGRRY 207
>X04300-1|CAA27843.1| 512|Homo sapiens P-450 c protein.
Length = 512
Score = 81.0 bits (191), Expect = 5e-15
Identities = 52/204 (25%), Positives = 101/204 (49%), Gaps = 12/204 (5%)
Frame = +2
Query: 155 LSSNMDLYFIWLVTFVAGFWIFK----KIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITL 322
+S + + + V F FW+ + ++ + PPGPWG P++G++ + + +PH+ L
Sbjct: 5 ISMSATEFLLASVIFCLVFWVIRASRPQVPKGLKNPPGPWGWPLIGHMLTLGK-NPHLAL 63
Query: 323 TNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSK--DSFSGRAPLYLTHGLMNGNGIIC 496
+ +S+ YG + +++GS VVLS +R A + D F GR LY + NG +
Sbjct: 64 SRMSQQYGDVLQIRIGSTPVVVLSGLDTIRQALVRQGDDFKGRPDLYTFTLISNGQSMSF 123
Query: 497 A--EGGLWRDQRKLITSWLKSFGMSKHSVSREK--LEKRIASGVYEILENIEK--TSDAA 658
+ G +W +R+L + LKSF ++ S LE+ ++ ++ +++
Sbjct: 124 SPDSGPVWAARRRLAQNGLKSFSIASDPASSTSCYLEEHVSKEAEVLISTLQELMAGPGH 183
Query: 659 LDLPHMLTNSLGNVVNEIIFGFKF 730
+ + S+ NV+ I FG ++
Sbjct: 184 FNPYRYVVVSVTNVICAICFGRRY 207
>X02612-1|CAA26458.1| 512|Homo sapiens cytochrome P(1)-450 protein.
Length = 512
Score = 81.0 bits (191), Expect = 5e-15
Identities = 52/204 (25%), Positives = 101/204 (49%), Gaps = 12/204 (5%)
Frame = +2
Query: 155 LSSNMDLYFIWLVTFVAGFWIFK----KIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITL 322
+S + + + V F FW+ + ++ + PPGPWG P++G++ + + +PH+ L
Sbjct: 5 ISMSATEFLLASVIFCLVFWVIRASRPQVPKGLKNPPGPWGWPLIGHMLTLGK-NPHLAL 63
Query: 323 TNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSK--DSFSGRAPLYLTHGLMNGNGIIC 496
+ +S+ YG + +++GS VVLS +R A + D F GR LY + NG +
Sbjct: 64 SRMSQQYGDVLQIRIGSTPVVVLSGLDTIRQALVRQGDDFKGRPDLYTFTLISNGQSMSF 123
Query: 497 A--EGGLWRDQRKLITSWLKSFGMSKHSVSREK--LEKRIASGVYEILENIEK--TSDAA 658
+ G +W +R+L + LKSF ++ S LE+ ++ ++ +++
Sbjct: 124 SPDSGPVWAARRRLAQNGLKSFSIASDPASSTSCYLEEHVSKEAEVLISTLQELMAGPGH 183
Query: 659 LDLPHMLTNSLGNVVNEIIFGFKF 730
+ + S+ NV+ I FG ++
Sbjct: 184 FNPYRYVVVSVTNVICAICFGRRY 207
>U22029-1|AAB40520.1| 494|Homo sapiens cytochrome P450 protein.
Length = 494
Score = 81.0 bits (191), Expect = 5e-15
Identities = 50/179 (27%), Positives = 86/179 (48%), Gaps = 2/179 (1%)
Frame = +2
Query: 215 IFKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLS 394
++++ K LPPGP LP +G ++ H ++ S+ YG ++ + +G VVL
Sbjct: 23 VWQQRKSRGKLPPGPTPLPFIGNYLQLNTEHICDSIMKFSECYGPVFTIHLGPRRVVVLC 82
Query: 395 DHKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSK 568
H VR+A + FSGR + G G+ + G + + + L+ FG+ K
Sbjct: 83 GHDAVREALVDQAEEFSGRGEQATFEWVFKGYGVAFSNGERAKQLLRFAIATLRDFGVGK 142
Query: 569 HSVSREKLEKRIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGFKFPPEDK 745
+ E+RI ++E I T A +D L+ ++ NV++ I+FG +F EDK
Sbjct: 143 RGI-----EERIQEESGFLIEAIRSTHGANIDPTFFLSRTVSNVISSIVFGDRFDYEDK 196
>K03191-1|AAA52139.1| 512|Homo sapiens CYP1A1 protein.
Length = 512
Score = 81.0 bits (191), Expect = 5e-15
Identities = 52/204 (25%), Positives = 101/204 (49%), Gaps = 12/204 (5%)
Frame = +2
Query: 155 LSSNMDLYFIWLVTFVAGFWIFK----KIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITL 322
+S + + + V F FW+ + ++ + PPGPWG P++G++ + + +PH+ L
Sbjct: 5 ISMSATEFLLASVIFCLVFWVMRASRPQVPKGLKNPPGPWGWPLIGHMLTLGK-NPHLAL 63
Query: 323 TNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSK--DSFSGRAPLYLTHGLMNGNGIIC 496
+ +S+ YG + +++GS VVLS +R A + D F GR LY + NG +
Sbjct: 64 SRMSQQYGDVLQIRIGSTPVVVLSGLDTIRQALVRQGDDFKGRPDLYTFTLISNGQSMSF 123
Query: 497 A--EGGLWRDQRKLITSWLKSFGMSKHSVSREK--LEKRIASGVYEILENIEK--TSDAA 658
+ G +W +R+L + LKSF ++ S LE+ ++ ++ +++
Sbjct: 124 SPDSGPVWAARRRLAQNGLKSFSIASDPASSTSCYLEEHVSKEAEVLISTLQELMAGPGH 183
Query: 659 LDLPHMLTNSLGNVVNEIIFGFKF 730
+ + S+ NV+ I FG ++
Sbjct: 184 FNPYRYVVVSVTNVICAICFGRRY 207
>EF094025-1|ABK41999.1| 512|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 1 protein.
Length = 512
Score = 81.0 bits (191), Expect = 5e-15
Identities = 52/204 (25%), Positives = 101/204 (49%), Gaps = 12/204 (5%)
Frame = +2
Query: 155 LSSNMDLYFIWLVTFVAGFWIFK----KIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITL 322
+S + + + V F FW+ + ++ + PPGPWG P++G++ + + +PH+ L
Sbjct: 5 ISMSATEFLLASVIFCLVFWVIRASRPQVPKGLKNPPGPWGWPLIGHMLTLGK-NPHLAL 63
Query: 323 TNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSK--DSFSGRAPLYLTHGLMNGNGIIC 496
+ +S+ YG + +++GS VVLS +R A + D F GR LY + NG +
Sbjct: 64 SRMSQQYGDVLQIRIGSTPVVVLSGLDTIRQALVRQGDDFKGRPDLYTFTLISNGQSMSF 123
Query: 497 A--EGGLWRDQRKLITSWLKSFGMSKHSVSREK--LEKRIASGVYEILENIEK--TSDAA 658
+ G +W +R+L + LKSF ++ S LE+ ++ ++ +++
Sbjct: 124 SPDSGPVWAARRRLAQNGLKSFSIASDPASSTSCYLEEHVSKEAEVLISTLQELMAGPGH 183
Query: 659 LDLPHMLTNSLGNVVNEIIFGFKF 730
+ + S+ NV+ I FG ++
Sbjct: 184 FNPYRYVVVSVTNVICAICFGRRY 207
>BC023019-1|AAH23019.1| 512|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 1 protein.
Length = 512
Score = 81.0 bits (191), Expect = 5e-15
Identities = 52/204 (25%), Positives = 101/204 (49%), Gaps = 12/204 (5%)
Frame = +2
Query: 155 LSSNMDLYFIWLVTFVAGFWIFK----KIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITL 322
+S + + + V F FW+ + ++ + PPGPWG P++G++ + + +PH+ L
Sbjct: 5 ISMSATEFLLASVIFCLVFWVIRASRPQVPKGLKNPPGPWGWPLIGHMLTLGK-NPHLAL 63
Query: 323 TNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSK--DSFSGRAPLYLTHGLMNGNGIIC 496
+ +S+ YG + +++GS VVLS +R A + D F GR LY + NG +
Sbjct: 64 SRMSQQYGDVLQIRIGSTPVVVLSGLDTIRQALVRQGDDFKGRPDLYTFTLISNGQSMSF 123
Query: 497 A--EGGLWRDQRKLITSWLKSFGMSKHSVSREK--LEKRIASGVYEILENIEK--TSDAA 658
+ G +W +R+L + LKSF ++ S LE+ ++ ++ +++
Sbjct: 124 SPDSGPVWAARRRLAQNGLKSFSIASDPASSTSCYLEEHVSKEAEVLISTLQELMAGPGH 183
Query: 659 LDLPHMLTNSLGNVVNEIIFGFKF 730
+ + S+ NV+ I FG ++
Sbjct: 184 FNPYRYVVVSVTNVICAICFGRRY 207
>AY310359-1|AAQ76692.1| 484|Homo sapiens cytochrome P450 1A1
variant protein.
Length = 484
Score = 81.0 bits (191), Expect = 5e-15
Identities = 52/204 (25%), Positives = 101/204 (49%), Gaps = 12/204 (5%)
Frame = +2
Query: 155 LSSNMDLYFIWLVTFVAGFWIFK----KIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITL 322
+S + + + V F FW+ + ++ + PPGPWG P++G++ + + +PH+ L
Sbjct: 5 ISMSATEFLLASVIFCLVFWVIRASRPQVPKGLKNPPGPWGWPLIGHMLTLGK-NPHLAL 63
Query: 323 TNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSK--DSFSGRAPLYLTHGLMNGNGIIC 496
+ +S+ YG + +++GS VVLS +R A + D F GR LY + NG +
Sbjct: 64 SRMSQQYGDVLQIRIGSTPVVVLSGLDTIRQALVRQGDDFKGRPDLYTFTLISNGQSMSF 123
Query: 497 A--EGGLWRDQRKLITSWLKSFGMSKHSVSREK--LEKRIASGVYEILENIEK--TSDAA 658
+ G +W +R+L + LKSF ++ S LE+ ++ ++ +++
Sbjct: 124 SPDSGPVWAARRRLAQNGLKSFSIASDPASSTSCYLEEHVSKEAEVLISTLQELMAGPGH 183
Query: 659 LDLPHMLTNSLGNVVNEIIFGFKF 730
+ + S+ NV+ I FG ++
Sbjct: 184 FNPYRYVVVSVTNVICAICFGRRY 207
>AM236046-1|CAJ84703.1| 229|Homo sapiens cytochrome P450 1A1
protein.
Length = 229
Score = 81.0 bits (191), Expect = 5e-15
Identities = 52/204 (25%), Positives = 101/204 (49%), Gaps = 12/204 (5%)
Frame = +2
Query: 155 LSSNMDLYFIWLVTFVAGFWIFK----KIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITL 322
+S + + + V F FW+ + ++ + PPGPWG P++G++ + + +PH+ L
Sbjct: 5 ISMSATEFLLASVIFCLVFWVIRASRPQVPKGLKNPPGPWGWPLIGHMLTLGK-NPHLAL 63
Query: 323 TNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSK--DSFSGRAPLYLTHGLMNGNGIIC 496
+ +S+ YG + +++GS VVLS +R A + D F GR LY + NG +
Sbjct: 64 SRMSQQYGDVLQIRIGSTPVVVLSGLDTIRQALVRQGDDFKGRPDLYTFTLISNGQSMSF 123
Query: 497 A--EGGLWRDQRKLITSWLKSFGMSKHSVSREK--LEKRIASGVYEILENIEK--TSDAA 658
+ G +W +R+L + LKSF ++ S LE+ ++ ++ +++
Sbjct: 124 SPDSGPVWAARRRLAQNGLKSFSIASDPASSTSCYLEEHVSKEAEVLISTLQELMAGPGH 183
Query: 659 LDLPHMLTNSLGNVVNEIIFGFKF 730
+ + S+ NV+ I FG ++
Sbjct: 184 FNPYRYVVVSVTNVICAICFGRRY 207
>AF253322-1|AAK25727.1| 512|Homo sapiens cytochrome P450 protein.
Length = 512
Score = 81.0 bits (191), Expect = 5e-15
Identities = 52/204 (25%), Positives = 101/204 (49%), Gaps = 12/204 (5%)
Frame = +2
Query: 155 LSSNMDLYFIWLVTFVAGFWIFK----KIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITL 322
+S + + + V F FW+ + ++ + PPGPWG P++G++ + + +PH+ L
Sbjct: 5 ISMSATEFLLASVIFCLVFWVIRASRPQVPKGLKNPPGPWGWPLIGHMLTLGK-NPHLAL 63
Query: 323 TNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSK--DSFSGRAPLYLTHGLMNGNGIIC 496
+ +S+ YG + +++GS VVLS +R A + D F GR LY + NG +
Sbjct: 64 SRMSQQYGDVLQIRIGSTPVVVLSGLDTIRQALVRQGDDFKGRPDLYTFTLISNGQSMSF 123
Query: 497 A--EGGLWRDQRKLITSWLKSFGMSKHSVSREK--LEKRIASGVYEILENIEK--TSDAA 658
+ G +W +R+L + LKSF ++ S LE+ ++ ++ +++
Sbjct: 124 SPDSGPVWAARRRLAQNGLKSFSIASDPASSTSCYLEEHVSKEAEVLISTLQELMAGPGH 183
Query: 659 LDLPHMLTNSLGNVVNEIIFGFKF 730
+ + S+ NV+ I FG ++
Sbjct: 184 FNPYRYVVVSVTNVICAICFGRRY 207
>X13930-1|CAA32118.1| 494|Homo sapiens protein ( Human CYP2A4 mRNA
for P-450 IIA4 protein. ).
Length = 494
Score = 80.2 bits (189), Expect = 8e-15
Identities = 48/179 (26%), Positives = 88/179 (49%), Gaps = 2/179 (1%)
Frame = +2
Query: 215 IFKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLS 394
++++ K LPPGP LP +G ++ + +L +S+ YG ++ + +G VVL
Sbjct: 23 VWQQRKSKGKLPPGPTPLPFIGNYLQLNTEQMYNSLMKISERYGPVFTIHLGPRRVVVLC 82
Query: 395 DHKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSK 568
H VR+A + FSGR + G G++ + G + R+ + L+ FG+ K
Sbjct: 83 GHDAVREALVDQAEEFSGRGEQATFDWVFKGYGVVFSNGERAKQLRRFSIATLRDFGVGK 142
Query: 569 HSVSREKLEKRIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGFKFPPEDK 745
+ E+RI +++ T A +D L+ ++ NV++ I+FG +F +DK
Sbjct: 143 RGI-----EERIQEEAGFLIDAHRGTGGANIDPTFFLSRTVSNVISSIVFGDRFDYKDK 196
>M61856-1|AAB59356.1| 490|Homo sapiens cytochrome protein.
Length = 490
Score = 80.2 bits (189), Expect = 8e-15
Identities = 51/169 (30%), Positives = 86/169 (50%), Gaps = 2/169 (1%)
Frame = +2
Query: 245 LPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAF- 421
LP GP LPI+G + +D +LTN SK YG ++ + G VVL ++ V++A
Sbjct: 29 LPSGPTPLPIIGNILQLDVKDMSKSLTNFSKVYGPVFTVYFGLKPIVVLHGYEAVKEALI 88
Query: 422 -SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSKHSVSREKLEK 598
+ FSGR + + G GI+ + G W++ R+ L++FGM K S+ E
Sbjct: 89 DHGEEFSGRGSFPVAEKVNKGLGILFSNGKRWKEIRRFCLMTLRNFGMGKRSI-----ED 143
Query: 599 RIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGFKFPPEDK 745
R+ ++E + KT+ + D +L + NV+ +IF +F +D+
Sbjct: 144 RVQEEARCLVEELRKTNASPCDPTFILGCAPCNVICSVIFHDRFDYKDQ 192
>L16876-1|AAA02630.1| 490|Homo sapiens cytochrome P-4502C18
protein.
Length = 490
Score = 80.2 bits (189), Expect = 8e-15
Identities = 51/169 (30%), Positives = 86/169 (50%), Gaps = 2/169 (1%)
Frame = +2
Query: 245 LPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAF- 421
LP GP LPI+G + +D +LTN SK YG ++ + G VVL ++ V++A
Sbjct: 29 LPSGPTPLPIIGNILQLDVKDMSKSLTNFSKVYGPVFTVYFGLKPIVVLHGYEAVKEALI 88
Query: 422 -SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSKHSVSREKLEK 598
+ FSGR + + G GI+ + G W++ R+ L++FGM K S+ E
Sbjct: 89 DHGEEFSGRGSFPVAEKVNKGLGILFSNGKRWKEIRRFCLMTLRNFGMGKRSI-----ED 143
Query: 599 RIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGFKFPPEDK 745
R+ ++E + KT+ + D +L + NV+ +IF +F +D+
Sbjct: 144 RVQEEARCLVEELRKTNASPCDPTFILGCAPCNVICSVIFHDRFDYKDQ 192
>BC096260-1|AAH96260.1| 431|Homo sapiens CYP2C18 protein protein.
Length = 431
Score = 80.2 bits (189), Expect = 8e-15
Identities = 51/169 (30%), Positives = 86/169 (50%), Gaps = 2/169 (1%)
Frame = +2
Query: 245 LPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAF- 421
LP GP LPI+G + +D +LTN SK YG ++ + G VVL ++ V++A
Sbjct: 29 LPSGPTPLPIIGNILQLDVKDMSKSLTNFSKVYGPVFTVYFGLKPIVVLHGYEAVKEALI 88
Query: 422 -SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSKHSVSREKLEK 598
+ FSGR + + G GI+ + G W++ R+ L++FGM K S+ E
Sbjct: 89 DHGEEFSGRGSFPVAEKVNKGLGILFSNGKRWKEIRRFCLMTLRNFGMGKRSI-----ED 143
Query: 599 RIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGFKFPPEDK 745
R+ ++E + KT+ + D +L + NV+ +IF +F +D+
Sbjct: 144 RVQEEARCLVEELRKTNASPCDPTFILGCAPCNVICSVIFHDRFDYKDQ 192
>BC096259-1|AAH96259.1| 443|Homo sapiens CYP2C18 protein protein.
Length = 443
Score = 80.2 bits (189), Expect = 8e-15
Identities = 51/169 (30%), Positives = 86/169 (50%), Gaps = 2/169 (1%)
Frame = +2
Query: 245 LPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAF- 421
LP GP LPI+G + +D +LTN SK YG ++ + G VVL ++ V++A
Sbjct: 29 LPSGPTPLPIIGNILQLDVKDMSKSLTNFSKVYGPVFTVYFGLKPIVVLHGYEAVKEALI 88
Query: 422 -SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSKHSVSREKLEK 598
+ FSGR + + G GI+ + G W++ R+ L++FGM K S+ E
Sbjct: 89 DHGEEFSGRGSFPVAEKVNKGLGILFSNGKRWKEIRRFCLMTLRNFGMGKRSI-----ED 143
Query: 599 RIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGFKFPPEDK 745
R+ ++E + KT+ + D +L + NV+ +IF +F +D+
Sbjct: 144 RVQEEARCLVEELRKTNASPCDPTFILGCAPCNVICSVIFHDRFDYKDQ 192
>BC096258-1|AAH96258.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 protein.
Length = 490
Score = 80.2 bits (189), Expect = 8e-15
Identities = 51/169 (30%), Positives = 86/169 (50%), Gaps = 2/169 (1%)
Frame = +2
Query: 245 LPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAF- 421
LP GP LPI+G + +D +LTN SK YG ++ + G VVL ++ V++A
Sbjct: 29 LPSGPTPLPIIGNILQLDVKDMSKSLTNFSKVYGPVFTVYFGLKPIVVLHGYEAVKEALI 88
Query: 422 -SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSKHSVSREKLEK 598
+ FSGR + + G GI+ + G W++ R+ L++FGM K S+ E
Sbjct: 89 DHGEEFSGRGSFPVAEKVNKGLGILFSNGKRWKEIRRFCLMTLRNFGMGKRSI-----ED 143
Query: 599 RIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGFKFPPEDK 745
R+ ++E + KT+ + D +L + NV+ +IF +F +D+
Sbjct: 144 RVQEEARCLVEELRKTNASPCDPTFILGCAPCNVICSVIFHDRFDYKDQ 192
>BC096257-1|AAH96257.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 protein.
Length = 490
Score = 80.2 bits (189), Expect = 8e-15
Identities = 51/169 (30%), Positives = 86/169 (50%), Gaps = 2/169 (1%)
Frame = +2
Query: 245 LPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAF- 421
LP GP LPI+G + +D +LTN SK YG ++ + G VVL ++ V++A
Sbjct: 29 LPSGPTPLPIIGNILQLDVKDMSKSLTNFSKVYGPVFTVYFGLKPIVVLHGYEAVKEALI 88
Query: 422 -SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSKHSVSREKLEK 598
+ FSGR + + G GI+ + G W++ R+ L++FGM K S+ E
Sbjct: 89 DHGEEFSGRGSFPVAEKVNKGLGILFSNGKRWKEIRRFCLMTLRNFGMGKRSI-----ED 143
Query: 599 RIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGFKFPPEDK 745
R+ ++E + KT+ + D +L + NV+ +IF +F +D+
Sbjct: 144 RVQEEARCLVEELRKTNASPCDPTFILGCAPCNVICSVIFHDRFDYKDQ 192
>BC096255-1|AAH96255.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 80.2 bits (189), Expect = 8e-15
Identities = 48/179 (26%), Positives = 88/179 (49%), Gaps = 2/179 (1%)
Frame = +2
Query: 215 IFKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLS 394
++++ K LPPGP LP +G ++ + +L +S+ YG ++ + +G VVL
Sbjct: 23 VWQQRKSKGKLPPGPTPLPFIGNYLQLNTEQMYNSLMKISERYGPVFTIHLGPRRVVVLC 82
Query: 395 DHKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSK 568
H VR+A + FSGR + G G++ + G + R+ + L+ FG+ K
Sbjct: 83 GHDAVREALVDQAEEFSGRGEQATFDWVFKGYGVVFSNGERAKQLRRFSIATLRDFGVGK 142
Query: 569 HSVSREKLEKRIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGFKFPPEDK 745
+ E+RI +++ T A +D L+ ++ NV++ I+FG +F +DK
Sbjct: 143 RGI-----EERIQEEAGFLIDAHRGTGGANIDPTFFLSRTVSNVISSIVFGDRFDYKDK 196
>BC069666-1|AAH69666.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 protein.
Length = 490
Score = 80.2 bits (189), Expect = 8e-15
Identities = 51/169 (30%), Positives = 86/169 (50%), Gaps = 2/169 (1%)
Frame = +2
Query: 245 LPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAF- 421
LP GP LPI+G + +D +LTN SK YG ++ + G VVL ++ V++A
Sbjct: 29 LPSGPTPLPIIGNILQLDVKDMSKSLTNFSKVYGPVFTVYFGLKPIVVLHGYEAVKEALI 88
Query: 422 -SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSKHSVSREKLEK 598
+ FSGR + + G GI+ + G W++ R+ L++FGM K S+ E
Sbjct: 89 DHGEEFSGRGSFPVAEKVNKGLGILFSNGKRWKEIRRFCLMTLRNFGMGKRSI-----ED 143
Query: 599 RIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGFKFPPEDK 745
R+ ++E + KT+ + D +L + NV+ +IF +F +D+
Sbjct: 144 RVQEEARCLVEELRKTNASPCDPTFILGCAPCNVICSVIFHDRFDYKDQ 192
>AL583836-1|CAH74067.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 protein.
Length = 490
Score = 80.2 bits (189), Expect = 8e-15
Identities = 51/169 (30%), Positives = 86/169 (50%), Gaps = 2/169 (1%)
Frame = +2
Query: 245 LPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAF- 421
LP GP LPI+G + +D +LTN SK YG ++ + G VVL ++ V++A
Sbjct: 29 LPSGPTPLPIIGNILQLDVKDMSKSLTNFSKVYGPVFTVYFGLKPIVVLHGYEAVKEALI 88
Query: 422 -SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSKHSVSREKLEK 598
+ FSGR + + G GI+ + G W++ R+ L++FGM K S+ E
Sbjct: 89 DHGEEFSGRGSFPVAEKVNKGLGILFSNGKRWKEIRRFCLMTLRNFGMGKRSI-----ED 143
Query: 599 RIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGFKFPPEDK 745
R+ ++E + KT+ + D +L + NV+ +IF +F +D+
Sbjct: 144 RVQEEARCLVEELRKTNASPCDPTFILGCAPCNVICSVIFHDRFDYKDQ 192
>AF182274-1|AAF13599.1| 516|Homo sapiens cytochrome P450-1A2
protein.
Length = 516
Score = 79.4 bits (187), Expect = 1e-14
Identities = 48/191 (25%), Positives = 95/191 (49%), Gaps = 12/191 (6%)
Frame = +2
Query: 197 FVAGFWIFK----KIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLK 364
F FW+ K ++ + PP PWG P++G++ + + +PH+ L+ +S+ YG + ++
Sbjct: 21 FCLVFWVLKGLRPRVPKGLKSPPEPWGWPLLGHVLTLGK-NPHLALSRMSQRYGDVLQIR 79
Query: 365 MGSIYAVVLSDHKLVRDAFSK--DSFSGRAPLYLTHGLMNGNGIICA--EGGLWRDQRKL 532
+GS +VLS +R A + D F GR LY + + +G + + G +W +R+L
Sbjct: 80 IGSTPVLVLSRLDTIRQALVRQGDDFKGRPDLYTSTLITDGQSLTFSTDSGPVWAARRRL 139
Query: 533 ITSWLKSFGMSKHSVSREK--LEKRIASGVYEILENIEK--TSDAALDLPHMLTNSLGNV 700
+ L +F ++ S LE+ ++ ++ +++ D + + S+ NV
Sbjct: 140 AQNALNTFSIASDPASSSSCYLEEHVSKEAMALISRLQELMAGPGHFDPYNQVVVSVANV 199
Query: 701 VNEIIFGFKFP 733
+ + FG FP
Sbjct: 200 IGAMCFGQHFP 210
>Z00036-1|CAA77335.1| 515|Homo sapiens protein ( Human mRNA for
cytochrome P-3-450. ).
Length = 515
Score = 79.0 bits (186), Expect = 2e-14
Identities = 48/191 (25%), Positives = 95/191 (49%), Gaps = 12/191 (6%)
Frame = +2
Query: 197 FVAGFWIFK----KIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLK 364
F FW+ K ++ + PP PWG P++G++ + + +PH+ L+ +S+ YG + ++
Sbjct: 21 FCLVFWVLKGLRPRVPKGLKSPPEPWGWPLLGHVLTLGK-NPHLALSRMSQRYGDVLQIR 79
Query: 365 MGSIYAVVLSDHKLVRDAFSK--DSFSGRAPLYLTHGLMNGNGIICA--EGGLWRDQRKL 532
+GS +VLS +R A + D F GR LY + + +G + + G +W +R+L
Sbjct: 80 IGSTPVLVLSRLDTIRQALVRQGDDFKGRPDLYTSTLITDGQSLTFSTDSGPVWAARRRL 139
Query: 533 ITSWLKSFGMSKHSVSREK--LEKRIASGVYEILENIEK--TSDAALDLPHMLTNSLGNV 700
+ L +F ++ S LE+ ++ ++ +++ D + + S+ NV
Sbjct: 140 AQNALNTFSIASDPASSSSCYLEEHVSKEAKALISRLQELMAGPGHFDPYNQVVVSVANV 199
Query: 701 VNEIIFGFKFP 733
+ + FG FP
Sbjct: 200 IGAMCFGQHFP 210
>M55053-1|AAA52146.1| 515|Homo sapiens cytochrome P3-450 protein.
Length = 515
Score = 79.0 bits (186), Expect = 2e-14
Identities = 48/191 (25%), Positives = 95/191 (49%), Gaps = 12/191 (6%)
Frame = +2
Query: 197 FVAGFWIFK----KIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLK 364
F FW+ K ++ + PP PWG P++G++ + + +PH+ L+ +S+ YG + ++
Sbjct: 21 FCLVFWVLKGLRPRVPKGLKSPPEPWGWPLLGHVLTLGK-NPHLALSRMSQRYGDVLQIR 79
Query: 365 MGSIYAVVLSDHKLVRDAFSK--DSFSGRAPLYLTHGLMNGNGIICA--EGGLWRDQRKL 532
+GS +VLS +R A + D F GR LY + + +G + + G +W +R+L
Sbjct: 80 IGSTPVLVLSRLDTIRQALVRQGDDFKGRPDLYTSTLITDGQSLTFSTDSGPVWAARRRL 139
Query: 533 ITSWLKSFGMSKHSVSREK--LEKRIASGVYEILENIEK--TSDAALDLPHMLTNSLGNV 700
+ L +F ++ S LE+ ++ ++ +++ D + + S+ NV
Sbjct: 140 AQNALNTFSIASDPASSSSCYLEEHVSKEAKALISRLQELMAGPGHFDPYNQVVVSVANV 199
Query: 701 VNEIIFGFKFP 733
+ + FG FP
Sbjct: 200 IGAMCFGQHFP 210
>M33317-1|AAA52138.1| 494|Homo sapiens CYP2A protein.
Length = 494
Score = 79.0 bits (186), Expect = 2e-14
Identities = 49/179 (27%), Positives = 86/179 (48%), Gaps = 2/179 (1%)
Frame = +2
Query: 215 IFKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLS 394
++++ K LPPGP LP +G ++ H ++ S+ YG ++ + +G VVL
Sbjct: 23 VWQQRKSRGKLPPGPTPLPFIGNYLQLNTEHICDSIMKFSECYGPVFTIHLGPRRVVVLC 82
Query: 395 DHKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSK 568
H VR+A + FSGR + G G+ + G + + + L+ FG+ K
Sbjct: 83 GHDAVREALVDQAEEFSGRGEQATFDWVFKGYGVAFSNGERAKQLLRFAIATLRDFGVGK 142
Query: 569 HSVSREKLEKRIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGFKFPPEDK 745
+ E+RI ++E I + A +D L+ ++ NV++ I+FG +F EDK
Sbjct: 143 RGI-----EERIQEESGFLIEAIRSSHGANIDPTFFLSRTVSNVISSIVFGDRFDYEDK 196
>M31667-1|AAA52163.1| 515|Homo sapiens CYP1A2 protein.
Length = 515
Score = 79.0 bits (186), Expect = 2e-14
Identities = 48/191 (25%), Positives = 95/191 (49%), Gaps = 12/191 (6%)
Frame = +2
Query: 197 FVAGFWIFK----KIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLK 364
F FW+ K ++ + PP PWG P++G++ + + +PH+ L+ +S+ YG + ++
Sbjct: 21 FCLVFWVLKGLRPRVPKGLKSPPEPWGWPLLGHVLTLGK-NPHLALSRMSQRYGDVLQIR 79
Query: 365 MGSIYAVVLSDHKLVRDAFSK--DSFSGRAPLYLTHGLMNGNGIICA--EGGLWRDQRKL 532
+GS +VLS +R A + D F GR LY + + +G + + G +W +R+L
Sbjct: 80 IGSTPVLVLSRLDTIRQALVRQGDDFKGRPDLYTSTLITDGQSLTFSTDSGPVWAARRRL 139
Query: 533 ITSWLKSFGMSKHSVSREK--LEKRIASGVYEILENIEK--TSDAALDLPHMLTNSLGNV 700
+ L +F ++ S LE+ ++ ++ +++ D + + S+ NV
Sbjct: 140 AQNALNTFSIASDPASSSSCYLEEHVSKEAKALISRLQELMAGPGHFDPYNQVVVSVANV 199
Query: 701 VNEIIFGFKFP 733
+ + FG FP
Sbjct: 200 IGAMCFGQHFP 210
>DQ022432-1|AAY26399.1| 516|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 2 protein.
Length = 516
Score = 79.0 bits (186), Expect = 2e-14
Identities = 48/191 (25%), Positives = 95/191 (49%), Gaps = 12/191 (6%)
Frame = +2
Query: 197 FVAGFWIFK----KIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLK 364
F FW+ K ++ + PP PWG P++G++ + + +PH+ L+ +S+ YG + ++
Sbjct: 21 FCLVFWVLKGLRPRVPKGLKSPPEPWGWPLLGHVLTLGK-NPHLALSRMSQRYGDVLQIR 79
Query: 365 MGSIYAVVLSDHKLVRDAFSK--DSFSGRAPLYLTHGLMNGNGIICA--EGGLWRDQRKL 532
+GS +VLS +R A + D F GR LY + + +G + + G +W +R+L
Sbjct: 80 IGSTPVLVLSRLDTIRQALVRQGDDFKGRPDLYTSTLITDGQSLTFSTDSGPVWAARRRL 139
Query: 533 ITSWLKSFGMSKHSVSREK--LEKRIASGVYEILENIEK--TSDAALDLPHMLTNSLGNV 700
+ L +F ++ S LE+ ++ ++ +++ D + + S+ NV
Sbjct: 140 AQNALNTFSIASDPASSSSCYLEEHVSKEAKALISRLQELMAGPGHFDPYNQVVVSVANV 199
Query: 701 VNEIIFGFKFP 733
+ + FG FP
Sbjct: 200 IGAMCFGQHFP 210
>BC067429-1|AAH67429.1| 516|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 2 protein.
Length = 516
Score = 79.0 bits (186), Expect = 2e-14
Identities = 48/191 (25%), Positives = 95/191 (49%), Gaps = 12/191 (6%)
Frame = +2
Query: 197 FVAGFWIFK----KIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLK 364
F FW+ K ++ + PP PWG P++G++ + + +PH+ L+ +S+ YG + ++
Sbjct: 21 FCLVFWVLKGLRPRVPKGLKSPPEPWGWPLLGHVLTLGK-NPHLALSRMSQRYGDVLQIR 79
Query: 365 MGSIYAVVLSDHKLVRDAFSK--DSFSGRAPLYLTHGLMNGNGIICA--EGGLWRDQRKL 532
+GS +VLS +R A + D F GR LY + + +G + + G +W +R+L
Sbjct: 80 IGSTPVLVLSRLDTIRQALVRQGDDFKGRPDLYTSTLITDGQSLTFSTDSGPVWAARRRL 139
Query: 533 ITSWLKSFGMSKHSVSREK--LEKRIASGVYEILENIEK--TSDAALDLPHMLTNSLGNV 700
+ L +F ++ S LE+ ++ ++ +++ D + + S+ NV
Sbjct: 140 AQNALNTFSIASDPASSSSCYLEEHVSKEAKALISRLQELMAGPGHFDPYNQVVVSVANV 199
Query: 701 VNEIIFGFKFP 733
+ + FG FP
Sbjct: 200 IGAMCFGQHFP 210
>BC067428-1|AAH67428.1| 516|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 2 protein.
Length = 516
Score = 79.0 bits (186), Expect = 2e-14
Identities = 48/191 (25%), Positives = 95/191 (49%), Gaps = 12/191 (6%)
Frame = +2
Query: 197 FVAGFWIFK----KIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLK 364
F FW+ K ++ + PP PWG P++G++ + + +PH+ L+ +S+ YG + ++
Sbjct: 21 FCLVFWVLKGLRPRVPKGLKSPPEPWGWPLLGHVLTLGK-NPHLALSRMSQRYGDVLQIR 79
Query: 365 MGSIYAVVLSDHKLVRDAFSK--DSFSGRAPLYLTHGLMNGNGIICA--EGGLWRDQRKL 532
+GS +VLS +R A + D F GR LY + + +G + + G +W +R+L
Sbjct: 80 IGSTPVLVLSRLDTIRQALVRQGDDFKGRPDLYTSTLITDGQSLTFSTDSGPVWAARRRL 139
Query: 533 ITSWLKSFGMSKHSVSREK--LEKRIASGVYEILENIEK--TSDAALDLPHMLTNSLGNV 700
+ L +F ++ S LE+ ++ ++ +++ D + + S+ NV
Sbjct: 140 AQNALNTFSIASDPASSSSCYLEEHVSKEAKALISRLQELMAGPGHFDPYNQVVVSVANV 199
Query: 701 VNEIIFGFKFP 733
+ + FG FP
Sbjct: 200 IGAMCFGQHFP 210
>BC067426-1|AAH67426.1| 516|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 2 protein.
Length = 516
Score = 79.0 bits (186), Expect = 2e-14
Identities = 48/191 (25%), Positives = 95/191 (49%), Gaps = 12/191 (6%)
Frame = +2
Query: 197 FVAGFWIFK----KIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLK 364
F FW+ K ++ + PP PWG P++G++ + + +PH+ L+ +S+ YG + ++
Sbjct: 21 FCLVFWVLKGLRPRVPKGLKSPPEPWGWPLLGHVLTLGK-NPHLALSRMSQRYGDVLQIR 79
Query: 365 MGSIYAVVLSDHKLVRDAFSK--DSFSGRAPLYLTHGLMNGNGIICA--EGGLWRDQRKL 532
+GS +VLS +R A + D F GR LY + + +G + + G +W +R+L
Sbjct: 80 IGSTPVLVLSRLDTIRQALVRQGDDFKGRPDLYTSTLITDGQSLTFSTDSGPVWAARRRL 139
Query: 533 ITSWLKSFGMSKHSVSREK--LEKRIASGVYEILENIEK--TSDAALDLPHMLTNSLGNV 700
+ L +F ++ S LE+ ++ ++ +++ D + + S+ NV
Sbjct: 140 AQNALNTFSIASDPASSSSCYLEEHVSKEAKALISRLQELMAGPGHFDPYNQVVVSVANV 199
Query: 701 VNEIIFGFKFP 733
+ + FG FP
Sbjct: 200 IGAMCFGQHFP 210
>BC067425-1|AAH67425.1| 516|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 2 protein.
Length = 516
Score = 79.0 bits (186), Expect = 2e-14
Identities = 48/191 (25%), Positives = 95/191 (49%), Gaps = 12/191 (6%)
Frame = +2
Query: 197 FVAGFWIFK----KIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLK 364
F FW+ K ++ + PP PWG P++G++ + + +PH+ L+ +S+ YG + ++
Sbjct: 21 FCLVFWVLKGLRPRVPKGLKSPPEPWGWPLLGHVLTLGK-NPHLALSRMSQRYGDVLQIR 79
Query: 365 MGSIYAVVLSDHKLVRDAFSK--DSFSGRAPLYLTHGLMNGNGIICA--EGGLWRDQRKL 532
+GS +VLS +R A + D F GR LY + + +G + + G +W +R+L
Sbjct: 80 IGSTPVLVLSRLDTIRQALVRQGDDFKGRPDLYTSTLITDGQSLTFSTDSGPVWAARRRL 139
Query: 533 ITSWLKSFGMSKHSVSREK--LEKRIASGVYEILENIEK--TSDAALDLPHMLTNSLGNV 700
+ L +F ++ S LE+ ++ ++ +++ D + + S+ NV
Sbjct: 140 AQNALNTFSIASDPASSSSCYLEEHVSKEAKALISRLQELMAGPGHFDPYNQVVVSVANV 199
Query: 701 VNEIIFGFKFP 733
+ + FG FP
Sbjct: 200 IGAMCFGQHFP 210
>BC067424-1|AAH67424.1| 516|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 2 protein.
Length = 516
Score = 79.0 bits (186), Expect = 2e-14
Identities = 48/191 (25%), Positives = 95/191 (49%), Gaps = 12/191 (6%)
Frame = +2
Query: 197 FVAGFWIFK----KIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLK 364
F FW+ K ++ + PP PWG P++G++ + + +PH+ L+ +S+ YG + ++
Sbjct: 21 FCLVFWVLKGLRPRVPKGLKSPPEPWGWPLLGHVLTLGK-NPHLALSRMSQRYGDVLQIR 79
Query: 365 MGSIYAVVLSDHKLVRDAFSK--DSFSGRAPLYLTHGLMNGNGIICA--EGGLWRDQRKL 532
+GS +VLS +R A + D F GR LY + + +G + + G +W +R+L
Sbjct: 80 IGSTPVLVLSRLDTIRQALVRQGDDFKGRPDLYTSTLITDGQSLTFSTDSGPVWAARRRL 139
Query: 533 ITSWLKSFGMSKHSVSREK--LEKRIASGVYEILENIEK--TSDAALDLPHMLTNSLGNV 700
+ L +F ++ S LE+ ++ ++ +++ D + + S+ NV
Sbjct: 140 AQNALNTFSIASDPASSSSCYLEEHVSKEAKALISRLQELMAGPGHFDPYNQVVVSVANV 199
Query: 701 VNEIIFGFKFP 733
+ + FG FP
Sbjct: 200 IGAMCFGQHFP 210
>AM233520-1|CAJ80723.1| 189|Homo sapiens cytochrome P450 1A1
protein.
Length = 189
Score = 79.0 bits (186), Expect = 2e-14
Identities = 46/173 (26%), Positives = 89/173 (51%), Gaps = 10/173 (5%)
Frame = +2
Query: 155 LSSNMDLYFIWLVTFVAGFWIFK----KIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITL 322
+S + + + V F FW+ + ++ + PPGPWG P++G++ + + +PH+ L
Sbjct: 5 ISMSATEFLLASVIFCLVFWVIRASRPQVPKGLKNPPGPWGWPLIGHMLTLGK-NPHLAL 63
Query: 323 TNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSK--DSFSGRAPLYLTHGLMNGNGIIC 496
+ +S+ YG + +++GS VVLS +R A + D F GR LY + NG +
Sbjct: 64 SRMSQQYGDVLQIRIGSTPVVVLSGLDTIRQALVRQGDDFKGRPDLYTFTLISNGQSMSF 123
Query: 497 A--EGGLWRDQRKLITSWLKSFGMSKHSVSREK--LEKRIASGVYEILENIEK 643
+ G +W +R+L + LKSF ++ S LE+ ++ ++ +++
Sbjct: 124 SPDSGPVWAARRRLAQNGLKSFSIASDPASSTSCYLEEHVSKEAEVLISTLQE 176
>AM233519-1|CAJ80722.1| 189|Homo sapiens cytochrome P450 1A1
protein.
Length = 189
Score = 79.0 bits (186), Expect = 2e-14
Identities = 46/173 (26%), Positives = 89/173 (51%), Gaps = 10/173 (5%)
Frame = +2
Query: 155 LSSNMDLYFIWLVTFVAGFWIFK----KIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITL 322
+S + + + V F FW+ + ++ + PPGPWG P++G++ + + +PH+ L
Sbjct: 5 ISMSATEFLLASVIFCLVFWVIRASRPQVPKGLKNPPGPWGWPLIGHMLTLGK-NPHLAL 63
Query: 323 TNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSK--DSFSGRAPLYLTHGLMNGNGIIC 496
+ +S+ YG + +++GS VVLS +R A + D F GR LY + NG +
Sbjct: 64 SRMSQQYGDVLQIRIGSTPVVVLSGLDTIRQALVRQGDDFKGRPDLYTFTLISNGQSMSF 123
Query: 497 A--EGGLWRDQRKLITSWLKSFGMSKHSVSREK--LEKRIASGVYEILENIEK 643
+ G +W +R+L + LKSF ++ S LE+ ++ ++ +++
Sbjct: 124 SPDSGPVWAARRRLAQNGLKSFSIASDPASSTSCYLEEHVSKEAEVLISTLQE 176
>AF253322-2|AAK25728.1| 516|Homo sapiens cytochrome P450 protein.
Length = 516
Score = 79.0 bits (186), Expect = 2e-14
Identities = 48/191 (25%), Positives = 95/191 (49%), Gaps = 12/191 (6%)
Frame = +2
Query: 197 FVAGFWIFK----KIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLK 364
F FW+ K ++ + PP PWG P++G++ + + +PH+ L+ +S+ YG + ++
Sbjct: 21 FCLVFWVLKGLRPRVPKGLKSPPEPWGWPLLGHVLTLGK-NPHLALSRMSQRYGDVLQIR 79
Query: 365 MGSIYAVVLSDHKLVRDAFSK--DSFSGRAPLYLTHGLMNGNGIICA--EGGLWRDQRKL 532
+GS +VLS +R A + D F GR LY + + +G + + G +W +R+L
Sbjct: 80 IGSTPVLVLSRLDTIRQALVRQGDDFKGRPDLYTSTLITDGQSLTFSTDSGPVWAARRRL 139
Query: 533 ITSWLKSFGMSKHSVSREK--LEKRIASGVYEILENIEK--TSDAALDLPHMLTNSLGNV 700
+ L +F ++ S LE+ ++ ++ +++ D + + S+ NV
Sbjct: 140 AQNALNTFSIASDPASSSSCYLEEHVSKEAKALISRLQELMAGPGHFDPYNQVVVSVANV 199
Query: 701 VNEIIFGFKFP 733
+ + FG FP
Sbjct: 200 IGAMCFGQHFP 210
>L00389-1|AAA35738.1| 516|Homo sapiens protein ( Human cytochrome
P-450 4 gene, exon 7, and three Alu repeats in the 3'
flank. ).
Length = 516
Score = 78.2 bits (184), Expect = 3e-14
Identities = 48/191 (25%), Positives = 94/191 (49%), Gaps = 12/191 (6%)
Frame = +2
Query: 197 FVAGFWIFK----KIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLK 364
F FW+ K ++ + PP PWG P++G++ + + +PH+ L+ +S+ YG + +
Sbjct: 21 FCLVFWVLKGLRPRVPKGLKSPPEPWGWPLLGHVLTLGK-NPHLALSRMSQRYGDVLQIS 79
Query: 365 MGSIYAVVLSDHKLVRDAFSK--DSFSGRAPLYLTHGLMNGNGIICA--EGGLWRDQRKL 532
+GS +VLS +R A + D F GR LY + + +G + + G +W +R+L
Sbjct: 80 IGSTPVLVLSRLDTIRQALVRQGDDFKGRPDLYTSTLITDGQSLTFSTDSGPVWAARRRL 139
Query: 533 ITSWLKSFGMSKHSVSREK--LEKRIASGVYEILENIEK--TSDAALDLPHMLTNSLGNV 700
+ L +F ++ S LE+ ++ ++ +++ D + + S+ NV
Sbjct: 140 AQNALNTFSIASDPASSSSCYLEEHVSKEAKALISRLQELMAGPGHFDPYNQVVVSVANV 199
Query: 701 VNEIIFGFKFP 733
+ + FG FP
Sbjct: 200 IGAMCFGQHFP 210
>AK223113-1|BAD96833.1| 512|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 1 variant protein.
Length = 512
Score = 78.2 bits (184), Expect = 3e-14
Identities = 51/204 (25%), Positives = 100/204 (49%), Gaps = 12/204 (5%)
Frame = +2
Query: 155 LSSNMDLYFIWLVTFVAGFWIFK----KIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITL 322
+S + + + V F FW+ + ++ + PPGPW P++G++ + + +PH+ L
Sbjct: 5 ISMSATEFLLASVIFCLVFWVIRASRPQVPKGLKNPPGPWDWPLIGHMLTLGK-NPHLAL 63
Query: 323 TNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSK--DSFSGRAPLYLTHGLMNGNGIIC 496
+ +S+ YG + +++GS VVLS +R A + D F GR LY + NG +
Sbjct: 64 SRMSQQYGDVLQIRIGSTPVVVLSGLDTIRQALVRQGDDFKGRPDLYTFTLISNGQSMSF 123
Query: 497 A--EGGLWRDQRKLITSWLKSFGMSKHSVSREK--LEKRIASGVYEILENIEK--TSDAA 658
+ G +W +R+L + LKSF ++ S LE+ ++ ++ +++
Sbjct: 124 SPDSGPVWAARRRLAQNGLKSFSIASDPASSTSCYLEEHVSKEAEVLISTLQELMAGPGH 183
Query: 659 LDLPHMLTNSLGNVVNEIIFGFKF 730
+ + S+ NV+ I FG ++
Sbjct: 184 FNPYRYVVVSVTNVICAICFGRRY 207
>L39098-1|AAL31347.1| 160|Homo sapiens S-mephenytoin 4-hydroxylase
protein.
Length = 160
Score = 77.8 bits (183), Expect = 4e-14
Identities = 47/136 (34%), Positives = 71/136 (52%), Gaps = 2/136 (1%)
Frame = +2
Query: 245 LPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFS 424
LPPGP LP++G + ID +LTNLSK YG ++ L G VVL +++V++A
Sbjct: 29 LPPGPTPLPVIGNILQIDIKDVSKSLTNLSKIYGPVFTLYFGLERMVVLHGYEVVKEALI 88
Query: 425 K--DSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSKHSVSREKLEK 598
+ FSGR L G GI+ + G W++ R+ L++FGM K S+ E
Sbjct: 89 DLGEEFSGRGHFPLAERANRGFGIVFSNGKRWKEIRRFSLMTLRNFGMGKRSI-----ED 143
Query: 599 RIASGVYEILENIEKT 646
R+ ++E + KT
Sbjct: 144 RVQEEARCLVEELRKT 159
>AK223510-1|BAD97230.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 variant protein.
Length = 490
Score = 77.8 bits (183), Expect = 4e-14
Identities = 50/169 (29%), Positives = 85/169 (50%), Gaps = 2/169 (1%)
Frame = +2
Query: 245 LPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAF- 421
LP GP LPI+G + +D +LTN SK YG ++ + G VVL ++ V++A
Sbjct: 29 LPSGPTPLPIIGNILQLDVKDMSKSLTNFSKVYGPVFTVYFGLKPIVVLHGYEAVKEALI 88
Query: 422 -SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSKHSVSREKLEK 598
+ F GR + + G GI+ + G W++ R+ L++FGM K S+ E
Sbjct: 89 DHGEEFFGRGSFPVAEKVNKGLGILFSNGKRWKEIRRFCLMTLRNFGMGKRSI-----ED 143
Query: 599 RIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGFKFPPEDK 745
R+ ++E + KT+ + D +L + NV+ +IF +F +D+
Sbjct: 144 RVQEEARCLVEELRKTNASPCDPTFILGCAPCNVICSVIFHDRFDYKDQ 192
>BC067427-1|AAH67427.1| 516|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 2 protein.
Length = 516
Score = 76.2 bits (179), Expect = 1e-13
Identities = 47/191 (24%), Positives = 94/191 (49%), Gaps = 12/191 (6%)
Frame = +2
Query: 197 FVAGFWIFK----KIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLK 364
F FW+ K ++ + PP PWG P++G++ + + +PH+ L+ +S+ YG + ++
Sbjct: 21 FCLVFWVLKGLRPRVPKGLKSPPEPWGWPLLGHVLTLGK-NPHLALSRMSQRYGDVLQIR 79
Query: 365 MGSIYAVVLSDHKLVRDAFSK--DSFSGRAPLYLTHGLMNGNGIICA--EGGLWRDQRKL 532
+ S +VLS +R A + D F GR LY + + +G + + G +W +R+L
Sbjct: 80 IDSTPVLVLSRLDTIRQALVRQGDDFKGRPDLYTSTLITDGQSLTFSTDSGPVWAARRRL 139
Query: 533 ITSWLKSFGMSKHSVSREK--LEKRIASGVYEILENIEK--TSDAALDLPHMLTNSLGNV 700
+ L +F ++ S LE+ ++ ++ +++ D + + S+ NV
Sbjct: 140 AQNALNTFSIASDPASSSSCYLEEHVSKEAKALISRLQELMAGPGHFDPYNQVVVSVANV 199
Query: 701 VNEIIFGFKFP 733
+ + FG FP
Sbjct: 200 IGAMCFGQHFP 210
>S63426-1|ABB76283.1| 214|Homo sapiens (S)-mephenytoin hydroxylase
associated cytochrome P450 protein.
Length = 214
Score = 75.8 bits (178), Expect = 2e-13
Identities = 50/169 (29%), Positives = 84/169 (49%), Gaps = 2/169 (1%)
Frame = +2
Query: 245 LPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAF- 421
LP GP LPI+G + +D +LTN SK YG ++ + G VVL ++ V++A
Sbjct: 29 LPSGPTPLPIIGNILQLDVKDMSKSLTNFSKVYGPVFTVYFGLKPIVVLHGYEAVKEALI 88
Query: 422 -SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSKHSVSREKLEK 598
+ FSGR + + G GI+ + G W++ + L++FGM K S+ E
Sbjct: 89 DHGEEFSGRGSFPVAEKVNKGLGILFSNGKRWKEIWRFCLMTLRNFGMGKRSI-----ED 143
Query: 599 RIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGFKFPPEDK 745
R+ ++E + KT+ + D +L + NV +IF +F +D+
Sbjct: 144 RVQEEARCLVEELRKTNASPCDPTFILGCAPCNVTCSVIFHDRFDYKDQ 192
>BC020754-1|AAH20754.1| 162|Homo sapiens CYP2C9 protein protein.
Length = 162
Score = 73.3 bits (172), Expect = 9e-13
Identities = 46/136 (33%), Positives = 69/136 (50%), Gaps = 2/136 (1%)
Frame = +2
Query: 245 LPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFS 424
LPPGP LP++G + I +LTNLSK YG ++ L G VVL ++ V++A
Sbjct: 29 LPPGPTPLPVIGNILQIGIKDISKSLTNLSKVYGPVFTLYFGLKPIVVLHGYEAVKEALI 88
Query: 425 K--DSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSKHSVSREKLEK 598
+ FSGR L G GI+ + G W++ R+ L++FGM K S+ E
Sbjct: 89 DLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIRRFSLMTLRNFGMGKRSI-----ED 143
Query: 599 RIASGVYEILENIEKT 646
R+ ++E + KT
Sbjct: 144 RVQEEARCLVEELRKT 159
>BC070317-1|AAH70317.1| 162|Homo sapiens CYP2C9 protein protein.
Length = 162
Score = 71.7 bits (168), Expect = 3e-12
Identities = 41/113 (36%), Positives = 60/113 (53%), Gaps = 2/113 (1%)
Frame = +2
Query: 245 LPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFS 424
LPPGP LP++G + I +LTNLSK YG ++ L G VVL ++ V++A
Sbjct: 29 LPPGPTPLPVIGNILQIGIKDISKSLTNLSKVYGPVFTLYFGLKPIVVLHGYEAVKEALI 88
Query: 425 K--DSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSKHSV 577
+ FSGR L G GI+ + G W++ R+ L++FGM K S+
Sbjct: 89 DLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIRRFSLMTLRNFGMGKRSI 141
>M63871-1|AAA59984.1| 508|Homo sapiens CYP17 protein.
Length = 508
Score = 70.1 bits (164), Expect = 8e-12
Identities = 56/197 (28%), Positives = 94/197 (47%), Gaps = 6/197 (3%)
Frame = +2
Query: 170 DLYFIWLVTFVAGFWIFKKIKEWQNLPPGPWGLPIVGYLPFIDRY-HPHITLTNLSKTYG 346
+L + L+T FW K+ P LP+VG LPF+ R+ H H L K YG
Sbjct: 3 ELVALLLLTLAYLFWP-KRRWPGAKYPKSLLSLPLVGSLPFLPRHGHMHNNFFKLQKKYG 61
Query: 347 AIYGLKMGSIYAVVLSDHKLVRDAFSK--DSFSGRAPLYLTHGLMNGN--GIICAEGGL- 511
IY ++MG+ V++ H+L ++ K FSGR P T + + N GI A+ G
Sbjct: 62 PIYSVRMGTKTTVIVGHHQLAKEVLIKKGKDFSGR-PQMATLDIASNNRKGIAFADSGAH 120
Query: 512 WRDQRKLITSWLKSFGMSKHSVSREKLEKRIASGVYEILENIEKTSDAALDLPHMLTNSL 691
W+ R+L + +F + K +KLEK I + + + + + ++D+ + ++
Sbjct: 121 WQLHRRLA---MATFALFKD--GDQKLEKIICQEISTLCDMLATHNGQSIDISFPVFVAV 175
Query: 692 GNVVNEIIFGFKFPPED 742
NV++ I F + D
Sbjct: 176 TNVISLICFNTSYKNGD 192
>M19489-1|AAA36405.1| 508|Homo sapiens CYP17 protein.
Length = 508
Score = 70.1 bits (164), Expect = 8e-12
Identities = 56/197 (28%), Positives = 94/197 (47%), Gaps = 6/197 (3%)
Frame = +2
Query: 170 DLYFIWLVTFVAGFWIFKKIKEWQNLPPGPWGLPIVGYLPFIDRY-HPHITLTNLSKTYG 346
+L + L+T FW K+ P LP+VG LPF+ R+ H H L K YG
Sbjct: 3 ELVALLLLTLAYLFWP-KRRWPGAKYPKSLLSLPLVGSLPFLPRHGHMHNNFFKLQKKYG 61
Query: 347 AIYGLKMGSIYAVVLSDHKLVRDAFSK--DSFSGRAPLYLTHGLMNGN--GIICAEGGL- 511
IY ++MG+ V++ H+L ++ K FSGR P T + + N GI A+ G
Sbjct: 62 PIYSVRMGTKTTVIVGHHQLAKEVLIKKGKDFSGR-PQMATLDIASNNRKGIAFADSGAH 120
Query: 512 WRDQRKLITSWLKSFGMSKHSVSREKLEKRIASGVYEILENIEKTSDAALDLPHMLTNSL 691
W+ R+L + +F + K +KLEK I + + + + + ++D+ + ++
Sbjct: 121 WQLHRRLA---MATFALFKD--GDQKLEKIICQEISTLCDMLATHNGQSIDISFPVFVAV 175
Query: 692 GNVVNEIIFGFKFPPED 742
NV++ I F + D
Sbjct: 176 TNVISLICFNTSYKNGD 192
>M14564-1|AAA52151.1| 508|Homo sapiens CYP17 protein.
Length = 508
Score = 70.1 bits (164), Expect = 8e-12
Identities = 56/197 (28%), Positives = 94/197 (47%), Gaps = 6/197 (3%)
Frame = +2
Query: 170 DLYFIWLVTFVAGFWIFKKIKEWQNLPPGPWGLPIVGYLPFIDRY-HPHITLTNLSKTYG 346
+L + L+T FW K+ P LP+VG LPF+ R+ H H L K YG
Sbjct: 3 ELVALLLLTLAYLFWP-KRRCPGAKYPKSLLSLPLVGSLPFLPRHGHMHNNFFKLQKKYG 61
Query: 347 AIYGLKMGSIYAVVLSDHKLVRDAFSK--DSFSGRAPLYLTHGLMNGN--GIICAEGGL- 511
IY ++MG+ V++ H+L ++ K FSGR P T + + N GI A+ G
Sbjct: 62 PIYSVRMGTKTTVIVGHHQLAKEVLIKKGKDFSGR-PQMATLDIASNNRKGIAFADSGAH 120
Query: 512 WRDQRKLITSWLKSFGMSKHSVSREKLEKRIASGVYEILENIEKTSDAALDLPHMLTNSL 691
W+ R+L + +F + K +KLEK I + + + + + ++D+ + ++
Sbjct: 121 WQLHRRLA---MATFALFKD--GDQKLEKIICQEISTLCDMLATHNGQSIDISFPVFVAV 175
Query: 692 GNVVNEIIFGFKFPPED 742
NV++ I F + D
Sbjct: 176 TNVISLICFNTSYKNGD 192
>DQ530598-1|ABF50972.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 70.1 bits (164), Expect = 8e-12
Identities = 56/197 (28%), Positives = 94/197 (47%), Gaps = 6/197 (3%)
Frame = +2
Query: 170 DLYFIWLVTFVAGFWIFKKIKEWQNLPPGPWGLPIVGYLPFIDRY-HPHITLTNLSKTYG 346
+L + L+T FW K+ P LP+VG LPF+ R+ H H L K YG
Sbjct: 3 ELVALLLLTLAYLFWP-KRRCPGAKYPKSLLSLPLVGSLPFLPRHGHMHNNFFKLQKKYG 61
Query: 347 AIYGLKMGSIYAVVLSDHKLVRDAFSK--DSFSGRAPLYLTHGLMNGN--GIICAEGGL- 511
IY ++MG+ V++ H+L ++ K FSGR P T + + N GI A+ G
Sbjct: 62 PIYSVRMGTKTTVIVGHHQLAKEVLIKKGKDFSGR-PQMATLDIASNNRKGIAFADSGAH 120
Query: 512 WRDQRKLITSWLKSFGMSKHSVSREKLEKRIASGVYEILENIEKTSDAALDLPHMLTNSL 691
W+ R+L + +F + K +KLEK I + + + + + ++D+ + ++
Sbjct: 121 WQLHRRLA---MATFALFKD--GDQKLEKIICQEISTLCDMLATHNGQSIDISFPVFVAV 175
Query: 692 GNVVNEIIFGFKFPPED 742
NV++ I F + D
Sbjct: 176 TNVISLICFNTSYKNGD 192
>BT020000-1|AAV38803.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 70.1 bits (164), Expect = 8e-12
Identities = 56/197 (28%), Positives = 94/197 (47%), Gaps = 6/197 (3%)
Frame = +2
Query: 170 DLYFIWLVTFVAGFWIFKKIKEWQNLPPGPWGLPIVGYLPFIDRY-HPHITLTNLSKTYG 346
+L + L+T FW K+ P LP+VG LPF+ R+ H H L K YG
Sbjct: 3 ELVALLLLTLAYLFWP-KRRCPGAKYPKSLLSLPLVGSLPFLPRHGHMHNNFFKLQKKYG 61
Query: 347 AIYGLKMGSIYAVVLSDHKLVRDAFSK--DSFSGRAPLYLTHGLMNGN--GIICAEGGL- 511
IY ++MG+ V++ H+L ++ K FSGR P T + + N GI A+ G
Sbjct: 62 PIYSVRMGTKTTVIVGHHQLAKEVLIKKGKDFSGR-PQMATLDIASNNRKGIAFADSGAH 120
Query: 512 WRDQRKLITSWLKSFGMSKHSVSREKLEKRIASGVYEILENIEKTSDAALDLPHMLTNSL 691
W+ R+L + +F + K +KLEK I + + + + + ++D+ + ++
Sbjct: 121 WQLHRRLA---MATFALFKD--GDQKLEKIICQEISTLCDMLATHNGQSIDISFPVFVAV 175
Query: 692 GNVVNEIIFGFKFPPED 742
NV++ I F + D
Sbjct: 176 TNVISLICFNTSYKNGD 192
>BC063388-1|AAH63388.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 70.1 bits (164), Expect = 8e-12
Identities = 56/197 (28%), Positives = 94/197 (47%), Gaps = 6/197 (3%)
Frame = +2
Query: 170 DLYFIWLVTFVAGFWIFKKIKEWQNLPPGPWGLPIVGYLPFIDRY-HPHITLTNLSKTYG 346
+L + L+T FW K+ P LP+VG LPF+ R+ H H L K YG
Sbjct: 3 ELVALLLLTLAYLFWP-KRRCPGAKYPKSLLSLPLVGSLPFLPRHGHMHNNFFKLQKKYG 61
Query: 347 AIYGLKMGSIYAVVLSDHKLVRDAFSK--DSFSGRAPLYLTHGLMNGN--GIICAEGGL- 511
IY ++MG+ V++ H+L ++ K FSGR P T + + N GI A+ G
Sbjct: 62 PIYSVRMGTKTTVIVGHHQLAKEVLIKKGKDFSGR-PQMATLDIASNNRKGIAFADSGAH 120
Query: 512 WRDQRKLITSWLKSFGMSKHSVSREKLEKRIASGVYEILENIEKTSDAALDLPHMLTNSL 691
W+ R+L + +F + K +KLEK I + + + + + ++D+ + ++
Sbjct: 121 WQLHRRLA---MATFALFKD--GDQKLEKIICQEISTLCDMLATHNGQSIDISFPVFVAV 175
Query: 692 GNVVNEIIFGFKFPPED 742
NV++ I F + D
Sbjct: 176 TNVISLICFNTSYKNGD 192
>BC062997-1|AAH62997.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 70.1 bits (164), Expect = 8e-12
Identities = 56/197 (28%), Positives = 94/197 (47%), Gaps = 6/197 (3%)
Frame = +2
Query: 170 DLYFIWLVTFVAGFWIFKKIKEWQNLPPGPWGLPIVGYLPFIDRY-HPHITLTNLSKTYG 346
+L + L+T FW K+ P LP+VG LPF+ R+ H H L K YG
Sbjct: 3 ELVALLLLTLAYLFWP-KRRCPGAKYPKSLLSLPLVGSLPFLPRHGHMHNNFFKLQKKYG 61
Query: 347 AIYGLKMGSIYAVVLSDHKLVRDAFSK--DSFSGRAPLYLTHGLMNGN--GIICAEGGL- 511
IY ++MG+ V++ H+L ++ K FSGR P T + + N GI A+ G
Sbjct: 62 PIYSVRMGTKTTVIVGHHQLAKEVLIKKGKDFSGR-PQMATLDIASNNRKGIAFADSGAH 120
Query: 512 WRDQRKLITSWLKSFGMSKHSVSREKLEKRIASGVYEILENIEKTSDAALDLPHMLTNSL 691
W+ R+L + +F + K +KLEK I + + + + + ++D+ + ++
Sbjct: 121 WQLHRRLA---MATFALFKD--GDQKLEKIICQEISTLCDMLATHNGQSIDISFPVFVAV 175
Query: 692 GNVVNEIIFGFKFPPED 742
NV++ I F + D
Sbjct: 176 TNVISLICFNTSYKNGD 192
>AL358790-3|CAI52498.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 70.1 bits (164), Expect = 8e-12
Identities = 56/197 (28%), Positives = 94/197 (47%), Gaps = 6/197 (3%)
Frame = +2
Query: 170 DLYFIWLVTFVAGFWIFKKIKEWQNLPPGPWGLPIVGYLPFIDRY-HPHITLTNLSKTYG 346
+L + L+T FW K+ P LP+VG LPF+ R+ H H L K YG
Sbjct: 3 ELVALLLLTLAYLFWP-KRRCPGAKYPKSLLSLPLVGSLPFLPRHGHMHNNFFKLQKKYG 61
Query: 347 AIYGLKMGSIYAVVLSDHKLVRDAFSK--DSFSGRAPLYLTHGLMNGN--GIICAEGGL- 511
IY ++MG+ V++ H+L ++ K FSGR P T + + N GI A+ G
Sbjct: 62 PIYSVRMGTKTTVIVGHHQLAKEVLIKKGKDFSGR-PQMATLDIASNNRKGIAFADSGAH 120
Query: 512 WRDQRKLITSWLKSFGMSKHSVSREKLEKRIASGVYEILENIEKTSDAALDLPHMLTNSL 691
W+ R+L + +F + K +KLEK I + + + + + ++D+ + ++
Sbjct: 121 WQLHRRLA---MATFALFKD--GDQKLEKIICQEISTLCDMLATHNGQSIDISFPVFVAV 175
Query: 692 GNVVNEIIFGFKFPPED 742
NV++ I F + D
Sbjct: 176 TNVISLICFNTSYKNGD 192
>M31153-1|AAA52140.1| 508|Homo sapiens CYP17 protein.
Length = 508
Score = 69.7 bits (163), Expect = 1e-11
Identities = 56/197 (28%), Positives = 94/197 (47%), Gaps = 6/197 (3%)
Frame = +2
Query: 170 DLYFIWLVTFVAGFWIFKKIKEWQNLPPGPWGLPIVGYLPFIDRY-HPHITLTNLSKTYG 346
+L + L+T FW K+ P LP+VG LPF+ R+ H H L K YG
Sbjct: 3 ELVALLLLTLAYLFWP-KRRCPGAKYPKSLLSLPLVGSLPFLPRHGHMHNNFFKLQKKYG 61
Query: 347 AIYGLKMGSIYAVVLSDHKLVRDAFSK--DSFSGRAPLYLTHGLMNGN--GIICAEGGL- 511
IY ++MG+ V++ H+L ++ K FSGR P T + + N GI A+ G
Sbjct: 62 PIYSVRMGTKTTVIVGHHQLAKEVLIKKGKDFSGR-PQMATLDIASNNRKGIAFADSGAH 120
Query: 512 WRDQRKLITSWLKSFGMSKHSVSREKLEKRIASGVYEILENIEKTSDAALDLPHMLTNSL 691
W+ R+L + +F + K +KLEK I + + + + + ++D+ + ++
Sbjct: 121 WQLHRRLA---MATFALFKD--GDQKLEKIICQEISTLSDMLATHNGQSIDISFPVFVAV 175
Query: 692 GNVVNEIIFGFKFPPED 742
NV++ I F + D
Sbjct: 176 TNVISLICFNTSYKNGD 192
>X13929-1|CAA32117.1| 448|Homo sapiens P-450 IIA3 protein (1 is 3rd
base in codon) protein.
Length = 448
Score = 66.9 bits (156), Expect = 8e-11
Identities = 39/145 (26%), Positives = 72/145 (49%), Gaps = 2/145 (1%)
Frame = +2
Query: 317 TLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGI 490
+L +S+ YG ++ + +G VVL H VR+A + FSGR + G G+
Sbjct: 11 SLMKISERYGPVFTIHLGPRRVVVLCGHDAVREALVDQAEEFSGRGEQATFDWVFKGYGV 70
Query: 491 ICAEGGLWRDQRKLITSWLKSFGMSKHSVSREKLEKRIASGVYEILENIEKTSDAALDLP 670
+ + G + R+ + L+ FG+ K + E+RI +++ + T A +D
Sbjct: 71 VFSNGERAKQLRRFSIATLRDFGVGKRGI-----EERIQEEAGFLIDALRGTGGANIDPT 125
Query: 671 HMLTNSLGNVVNEIIFGFKFPPEDK 745
L+ ++ NV++ I+FG +F +DK
Sbjct: 126 FFLSRTVSNVISSIVFGDRFDYKDK 150
>BC132767-1|AAI32768.1| 544|Homo sapiens cytochrome P450, family 2,
subfamily U, polypeptide 1 protein.
Length = 544
Score = 64.5 bits (150), Expect = 4e-10
Identities = 42/144 (29%), Positives = 73/144 (50%), Gaps = 3/144 (2%)
Frame = +2
Query: 308 PHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSKDS--FSGRAPLYLTHGLMNG 481
P + L +L++ YG+I+ +G VVLSD VR+A + + FS R + L +
Sbjct: 103 PQVLLAHLARVYGSIFSFFIGHYLVVVLSDFHSVREALVQQAEVFSDRPRVPLISIVTKE 162
Query: 482 NGIICAE-GGLWRDQRKLITSWLKSFGMSKHSVSREKLEKRIASGVYEILENIEKTSDAA 658
G++ A G +WR QRK S L+ FG+ K S LE +I + ++K +
Sbjct: 163 KGVVFAHYGPVWRQQRKFSHSTLRHFGLGKLS-----LEPKIIEEFKYVKAEMQKHGEDP 217
Query: 659 LDLPHMLTNSLGNVVNEIIFGFKF 730
+++N++ N++ + FG +F
Sbjct: 218 FCPFSIISNAVSNIICSLCFGQRF 241
>AY343323-1|AAQ21380.1| 544|Homo sapiens cytochrome P450 protein.
Length = 544
Score = 64.5 bits (150), Expect = 4e-10
Identities = 42/144 (29%), Positives = 73/144 (50%), Gaps = 3/144 (2%)
Frame = +2
Query: 308 PHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSKDS--FSGRAPLYLTHGLMNG 481
P + L +L++ YG+I+ +G VVLSD VR+A + + FS R + L +
Sbjct: 103 PQVLLAHLARVYGSIFSFFIGHYLVVVLSDFHSVREALVQQAEVFSDRPRVPLISIVTKE 162
Query: 482 NGIICAE-GGLWRDQRKLITSWLKSFGMSKHSVSREKLEKRIASGVYEILENIEKTSDAA 658
G++ A G +WR QRK S L+ FG+ K S LE +I + ++K +
Sbjct: 163 KGVVFAHYGPVWRQQRKFSHSTLRHFGLGKLS-----LEPKIIEEFKYVKAEMQKHGEDP 217
Query: 659 LDLPHMLTNSLGNVVNEIIFGFKF 730
+++N++ N++ + FG +F
Sbjct: 218 FCPFSIISNAVSNIICSLCFGQRF 241
>L07093-1|AAA36660.1| 468|Homo sapiens cytochrome P450 protein.
Length = 468
Score = 64.1 bits (149), Expect = 6e-10
Identities = 43/141 (30%), Positives = 70/141 (49%), Gaps = 2/141 (1%)
Frame = +2
Query: 329 LSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSK--DSFSGRAPLYLTHGLMNGNGIICAE 502
LSK YG ++ L G VVL +++V++A + FSGR L G GI+ +
Sbjct: 35 LSKIYGPVFTLYFGLERMVVLHGYEVVKEALIDLGEEFSGRGHFPLAERANRGFGIVFSN 94
Query: 503 GGLWRDQRKLITSWLKSFGMSKHSVSREKLEKRIASGVYEILENIEKTSDAALDLPHMLT 682
G W++ R+ L++FGM K S+ E R+ ++E + KT + D +L
Sbjct: 95 GKRWKEIRRFSLMTLRNFGMGKRSI-----EDRVQEEARCLVEELRKTKASPCDPTFILG 149
Query: 683 NSLGNVVNEIIFGFKFPPEDK 745
+ NV+ IIF +F +D+
Sbjct: 150 CAPCNVICSIIFQKRFDYKDQ 170
>BT020001-1|AAV38804.1| 543|Homo sapiens cytochrome P450, family 1,
subfamily B, polypeptide 1 protein.
Length = 543
Score = 64.1 bits (149), Expect = 6e-10
Identities = 47/196 (23%), Positives = 102/196 (52%), Gaps = 7/196 (3%)
Frame = +2
Query: 230 KEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLV 409
++ ++ PPGP+ P++G + + H++ L++ YG ++ +++GS VVL+ + +
Sbjct: 45 RQLRSAPPGPFAWPLIGNAAAVGQA-AHLSFARLARRYGDVFQIRLGSCPIVVLNGERAI 103
Query: 410 RDAFSK--DSFSGRAPLYLTHGLMNGNGIICAEGGL---WRDQRKLITSWLKSFGMSKHS 574
A + +F+ R P + + +++G G A G W+ QR+ S +++F ++
Sbjct: 104 HQALVQQGSAFADR-PAFASFRVVSG-GRSMAFGHYSEHWKVQRRAAHSMMRNF-FTRQP 160
Query: 575 VSREKLEKRIASGVYEILENIEK-TSDAALDLPHMLT-NSLGNVVNEIIFGFKFPPEDKT 748
SR+ LE + S E++ + + ++D A P LT ++ NV++ + FG ++ +D
Sbjct: 161 RSRQVLEGHVLSEARELVALLVRGSADGAFLDPRPLTVVAMANVMSAVCFGCRYSHDDPE 220
Query: 749 WQWFRQIQEEGCHXMG 796
++ EE +G
Sbjct: 221 FRELLSHNEEFGRTVG 236
>U56438-1|AAC50809.1| 543|Homo sapiens dioxin-inducible cytochrome
P450 protein.
Length = 543
Score = 63.7 bits (148), Expect = 7e-10
Identities = 47/196 (23%), Positives = 102/196 (52%), Gaps = 7/196 (3%)
Frame = +2
Query: 230 KEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLV 409
++ ++ PPGP+ P++G + + H++ L++ YG ++ +++GS VVL+ + +
Sbjct: 45 RQLRSAPPGPFAWPLIGNAAAVGQA-AHLSFARLARRYGDVFQIRLGSCPIVVLNGERAI 103
Query: 410 RDAFSK--DSFSGRAPLYLTHGLMNGNGIICAEGGL---WRDQRKLITSWLKSFGMSKHS 574
A + +F+ R P + + +++G G A G W+ QR+ S +++F ++
Sbjct: 104 HQALVQQGSAFADR-PAFASFRVVSG-GRSMAFGHYSEHWKVQRRAAHSMMRNF-FTRQP 160
Query: 575 VSREKLEKRIASGVYEILENIEK-TSDAALDLPHMLT-NSLGNVVNEIIFGFKFPPEDKT 748
SR+ LE + S E++ + + ++D A P LT ++ NV++ + FG ++ +D
Sbjct: 161 RSRQVLEGHVLSEARELVALLVRGSADGAFLDPRPLTVVAVANVMSAVCFGCRYSHDDPE 220
Query: 749 WQWFRQIQEEGCHXMG 796
++ EE +G
Sbjct: 221 FRELLSHNEEFGRTVG 236
>U03688-1|AAA19567.1| 543|Homo sapiens cytochrome P450 protein.
Length = 543
Score = 63.7 bits (148), Expect = 7e-10
Identities = 47/196 (23%), Positives = 102/196 (52%), Gaps = 7/196 (3%)
Frame = +2
Query: 230 KEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLV 409
++ ++ PPGP+ P++G + + H++ L++ YG ++ +++GS VVL+ + +
Sbjct: 45 RQLRSAPPGPFAWPLIGNAAAVGQA-AHLSFARLARRYGDVFQIRLGSCPIVVLNGERAI 103
Query: 410 RDAFSK--DSFSGRAPLYLTHGLMNGNGIICAEGGL---WRDQRKLITSWLKSFGMSKHS 574
A + +F+ R P + + +++G G A G W+ QR+ S +++F ++
Sbjct: 104 HQALVQQGSAFADR-PAFASFRVVSG-GRSMAFGHYSEHWKVQRRAAHSMMRNF-FTRQP 160
Query: 575 VSREKLEKRIASGVYEILENIEK-TSDAALDLPHMLT-NSLGNVVNEIIFGFKFPPEDKT 748
SR+ LE + S E++ + + ++D A P LT ++ NV++ + FG ++ +D
Sbjct: 161 RSRQVLEGHVLSEARELVALLVRGSADGAFLDPRPLTVVAVANVMSAVCFGCRYSHDDPE 220
Query: 749 WQWFRQIQEEGCHXMG 796
++ EE +G
Sbjct: 221 FRELLSHNEEFGRTVG 236
>DQ359216-1|ABC95161.1| 347|Homo sapiens dioxin-inducible
cytochrome P450 protein.
Length = 347
Score = 63.7 bits (148), Expect = 7e-10
Identities = 47/196 (23%), Positives = 102/196 (52%), Gaps = 7/196 (3%)
Frame = +2
Query: 230 KEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLV 409
++ ++ PPGP+ P++G + + H++ L++ YG ++ +++GS VVL+ + +
Sbjct: 45 RQLRSAPPGPFAWPLIGNAAAVGQA-AHLSFARLARRYGDVFQIRLGSCPIVVLNGERAI 103
Query: 410 RDAFSK--DSFSGRAPLYLTHGLMNGNGIICAEGGL---WRDQRKLITSWLKSFGMSKHS 574
A + +F+ R P + + +++G G A G W+ QR+ S +++F ++
Sbjct: 104 HQALVQQGSAFADR-PAFASFRVVSG-GRSMAFGHYSEHWKVQRRAAHSMMRNF-FTRQP 160
Query: 575 VSREKLEKRIASGVYEILENIEK-TSDAALDLPHMLT-NSLGNVVNEIIFGFKFPPEDKT 748
SR+ LE + S E++ + + ++D A P LT ++ NV++ + FG ++ +D
Sbjct: 161 RSRQVLEGHVLSEARELVALLVRGSADGAFLDPRPLTVVAVANVMSAVCFGCRYSHDDPE 220
Query: 749 WQWFRQIQEEGCHXMG 796
++ EE +G
Sbjct: 221 FRELLSHNEEFGRTVG 236
>BT019979-1|AAV38782.1| 543|Homo sapiens cytochrome P450, family 1,
subfamily B, polypeptide 1 protein.
Length = 543
Score = 63.7 bits (148), Expect = 7e-10
Identities = 47/196 (23%), Positives = 102/196 (52%), Gaps = 7/196 (3%)
Frame = +2
Query: 230 KEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLV 409
++ ++ PPGP+ P++G + + H++ L++ YG ++ +++GS VVL+ + +
Sbjct: 45 RQLRSAPPGPFAWPLIGNAAAVGQA-AHLSFARLARRYGDVFQIRLGSCPIVVLNGERAI 103
Query: 410 RDAFSK--DSFSGRAPLYLTHGLMNGNGIICAEGGL---WRDQRKLITSWLKSFGMSKHS 574
A + +F+ R P + + +++G G A G W+ QR+ S +++F ++
Sbjct: 104 HQALVQQGSAFADR-PAFASFRVVSG-GRSMAFGHYSEHWKVQRRAAHSMMRNF-FTRQP 160
Query: 575 VSREKLEKRIASGVYEILENIEK-TSDAALDLPHMLT-NSLGNVVNEIIFGFKFPPEDKT 748
SR+ LE + S E++ + + ++D A P LT ++ NV++ + FG ++ +D
Sbjct: 161 RSRQVLEGHVLSEARELVALLVRGSADGAFLDPRPLTVVAVANVMSAVCFGCRYSHDDPE 220
Query: 749 WQWFRQIQEEGCHXMG 796
++ EE +G
Sbjct: 221 FRELLSHNEEFGRTVG 236
>BC012049-1|AAH12049.1| 543|Homo sapiens cytochrome P450, family 1,
subfamily B, polypeptide 1 protein.
Length = 543
Score = 63.7 bits (148), Expect = 7e-10
Identities = 47/196 (23%), Positives = 102/196 (52%), Gaps = 7/196 (3%)
Frame = +2
Query: 230 KEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLV 409
++ ++ PPGP+ P++G + + H++ L++ YG ++ +++GS VVL+ + +
Sbjct: 45 RQLRSAPPGPFAWPLIGNAAAVGQA-AHLSFARLARRYGDVFQIRLGSCPIVVLNGERAI 103
Query: 410 RDAFSK--DSFSGRAPLYLTHGLMNGNGIICAEGGL---WRDQRKLITSWLKSFGMSKHS 574
A + +F+ R P + + +++G G A G W+ QR+ S +++F ++
Sbjct: 104 HQALVQQGSAFADR-PAFASFRVVSG-GRSMAFGHYSEHWKVQRRAAHSMMRNF-FTRQP 160
Query: 575 VSREKLEKRIASGVYEILENIEK-TSDAALDLPHMLT-NSLGNVVNEIIFGFKFPPEDKT 748
SR+ LE + S E++ + + ++D A P LT ++ NV++ + FG ++ +D
Sbjct: 161 RSRQVLEGHVLSEARELVALLVRGSADGAFLDPRPLTVVAVANVMSAVCFGCRYSHDDPE 220
Query: 749 WQWFRQIQEEGCHXMG 796
++ EE +G
Sbjct: 221 FRELLSHNEEFGRTVG 236
>AY393998-1|AAQ87875.1| 543|Homo sapiens cytochrome P450, family 1,
subfamily B, polypeptide 1 protein.
Length = 543
Score = 63.7 bits (148), Expect = 7e-10
Identities = 47/196 (23%), Positives = 102/196 (52%), Gaps = 7/196 (3%)
Frame = +2
Query: 230 KEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLV 409
++ ++ PPGP+ P++G + + H++ L++ YG ++ +++GS VVL+ + +
Sbjct: 45 RQLRSAPPGPFAWPLIGNAAAVGQA-AHLSFARLARRYGDVFQIRLGSCPIVVLNGERAI 103
Query: 410 RDAFSK--DSFSGRAPLYLTHGLMNGNGIICAEGGL---WRDQRKLITSWLKSFGMSKHS 574
A + +F+ R P + + +++G G A G W+ QR+ S +++F ++
Sbjct: 104 HQALVQQGSAFADR-PAFASFRVVSG-GRSMAFGHYSEHWKVQRRAAHSMMRNF-FTRQP 160
Query: 575 VSREKLEKRIASGVYEILENIEK-TSDAALDLPHMLT-NSLGNVVNEIIFGFKFPPEDKT 748
SR+ LE + S E++ + + ++D A P LT ++ NV++ + FG ++ +D
Sbjct: 161 RSRQVLEGHVLSEARELVALLVRGSADGAFLDPRPLTVVAVANVMSAVCFGCRYSHDDPE 220
Query: 749 WQWFRQIQEEGCHXMG 796
++ EE +G
Sbjct: 221 FRELLSHNEEFGRTVG 236
>AF450132-1|AAM50512.1| 543|Homo sapiens cytochrome P450 CYP1B1
protein.
Length = 543
Score = 63.7 bits (148), Expect = 7e-10
Identities = 47/196 (23%), Positives = 102/196 (52%), Gaps = 7/196 (3%)
Frame = +2
Query: 230 KEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLV 409
++ ++ PPGP+ P++G + + H++ L++ YG ++ +++GS VVL+ + +
Sbjct: 45 RQLRSAPPGPFAWPLIGNAAAVGQA-AHLSFARLARRYGDVFQIRLGSCPIVVLNGERAI 103
Query: 410 RDAFSK--DSFSGRAPLYLTHGLMNGNGIICAEGGL---WRDQRKLITSWLKSFGMSKHS 574
A + +F+ R P + + +++G G A G W+ QR+ S +++F ++
Sbjct: 104 HQALVQQGSAFADR-PAFASFRVVSG-GRSMAFGHYSEHWKVQRRAAHSMMRNF-FTRQP 160
Query: 575 VSREKLEKRIASGVYEILENIEK-TSDAALDLPHMLT-NSLGNVVNEIIFGFKFPPEDKT 748
SR+ LE + S E++ + + ++D A P LT ++ NV++ + FG ++ +D
Sbjct: 161 RSRQVLEGHVLSEARELVALLVRGSADGAFLDPRPLTVVAVANVMSAVCFGCRYSHDDPE 220
Query: 749 WQWFRQIQEEGCHXMG 796
++ EE +G
Sbjct: 221 FRELLSHNEEFGRTVG 236
>AC009229-2|AAY15039.1| 543|Homo sapiens unknown protein.
Length = 543
Score = 63.7 bits (148), Expect = 7e-10
Identities = 47/196 (23%), Positives = 102/196 (52%), Gaps = 7/196 (3%)
Frame = +2
Query: 230 KEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLV 409
++ ++ PPGP+ P++G + + H++ L++ YG ++ +++GS VVL+ + +
Sbjct: 45 RQLRSAPPGPFAWPLIGNAAAVGQA-AHLSFARLARRYGDVFQIRLGSCPIVVLNGERAI 103
Query: 410 RDAFSK--DSFSGRAPLYLTHGLMNGNGIICAEGGL---WRDQRKLITSWLKSFGMSKHS 574
A + +F+ R P + + +++G G A G W+ QR+ S +++F ++
Sbjct: 104 HQALVQQGSAFADR-PAFASFRVVSG-GRSMAFGHYSEHWKVQRRAAHSMMRNF-FTRQP 160
Query: 575 VSREKLEKRIASGVYEILENIEK-TSDAALDLPHMLT-NSLGNVVNEIIFGFKFPPEDKT 748
SR+ LE + S E++ + + ++D A P LT ++ NV++ + FG ++ +D
Sbjct: 161 RSRQVLEGHVLSEARELVALLVRGSADGAFLDPRPLTVVAVANVMSAVCFGCRYSHDDPE 220
Query: 749 WQWFRQIQEEGCHXMG 796
++ EE +G
Sbjct: 221 FRELLSHNEEFGRTVG 236
>BC025761-1|AAH25761.2| 490|Homo sapiens cytochrome P450, family 2,
subfamily W, polypeptide 1 protein.
Length = 490
Score = 60.5 bits (140), Expect = 7e-09
Identities = 34/119 (28%), Positives = 59/119 (49%), Gaps = 2/119 (1%)
Frame = +2
Query: 248 PPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFS- 424
PPGP LP+VG L + +L LS+ YG ++ + +G VVL+ + V++A +
Sbjct: 32 PPGPRPLPLVGNLHLLRLSQQDRSLMELSERYGPVFTVHLGRQKTVVLTGFEAVKEALAG 91
Query: 425 -KDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSKHSVSREKLEK 598
+ R P+ + + G GI + G WR R+ L S G+ + V+ + L++
Sbjct: 92 PGQELADRPPIAIFQLIQRGGGIFFSSGARWRAARQFTVRALHSLGVGREPVADKILQE 150
>X08006-1|CAA30807.1| 497|Homo sapiens cytochrome P450 db1 protein.
Length = 497
Score = 54.0 bits (124), Expect = 6e-07
Identities = 46/184 (25%), Positives = 80/184 (43%), Gaps = 6/184 (3%)
Frame = +2
Query: 248 PPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSK 427
PPGP LP +G L +D + L + +G ++ L++ VVL+ VR+A
Sbjct: 34 PPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVT 93
Query: 428 --DSFSGRAPLYLTHGLMNG---NGIICAE-GGLWRDQRKLITSWLKSFGMSKHSVSREK 589
+ + R P+ +T L G G+ A G WR+QR+ S L++ G+ K S
Sbjct: 94 HGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKS----- 148
Query: 590 LEKRIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGFKFPPEDKTWQWFRQI 769
LE+ + + S +L ++ NV+ + G +F +D + +
Sbjct: 149 LEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDL 208
Query: 770 QEEG 781
+EG
Sbjct: 209 AQEG 212
>M33388-1|AAA53500.1| 497|Homo sapiens cytochrome P450 IID6
protein.
Length = 497
Score = 54.0 bits (124), Expect = 6e-07
Identities = 46/184 (25%), Positives = 80/184 (43%), Gaps = 6/184 (3%)
Frame = +2
Query: 248 PPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSK 427
PPGP LP +G L +D + L + +G ++ L++ VVL+ VR+A
Sbjct: 34 PPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVT 93
Query: 428 --DSFSGRAPLYLTHGLMNG---NGIICAE-GGLWRDQRKLITSWLKSFGMSKHSVSREK 589
+ + R P+ +T L G G+ A G WR+QR+ S L++ G+ K S
Sbjct: 94 HGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKS----- 148
Query: 590 LEKRIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGFKFPPEDKTWQWFRQI 769
LE+ + + S +L ++ NV+ + G +F +D + +
Sbjct: 149 LEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDL 208
Query: 770 QEEG 781
+EG
Sbjct: 209 AQEG 212
>M20403-1|AAA52153.1| 497|Homo sapiens CYP2D protein.
Length = 497
Score = 54.0 bits (124), Expect = 6e-07
Identities = 46/184 (25%), Positives = 80/184 (43%), Gaps = 6/184 (3%)
Frame = +2
Query: 248 PPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSK 427
PPGP LP +G L +D + L + +G ++ L++ VVL+ VR+A
Sbjct: 34 PPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVT 93
Query: 428 --DSFSGRAPLYLTHGLMNG---NGIICAE-GGLWRDQRKLITSWLKSFGMSKHSVSREK 589
+ + R P+ +T L G G+ A G WR+QR+ S L++ G+ K S
Sbjct: 94 HGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKS----- 148
Query: 590 LEKRIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGFKFPPEDKTWQWFRQI 769
LE+ + + S +L ++ NV+ + G +F +D + +
Sbjct: 149 LEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDL 208
Query: 770 QEEG 781
+EG
Sbjct: 209 AQEG 212
>DQ282160-1|ABB77908.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 54.0 bits (124), Expect = 6e-07
Identities = 46/184 (25%), Positives = 80/184 (43%), Gaps = 6/184 (3%)
Frame = +2
Query: 248 PPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSK 427
PPGP LP +G L +D + L + +G ++ L++ VVL+ VR+A
Sbjct: 34 PPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVT 93
Query: 428 --DSFSGRAPLYLTHGLMNG---NGIICAE-GGLWRDQRKLITSWLKSFGMSKHSVSREK 589
+ + R P+ +T L G G+ A G WR+QR+ S L++ G+ K S
Sbjct: 94 HGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKS----- 148
Query: 590 LEKRIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGFKFPPEDKTWQWFRQI 769
LE+ + + S +L ++ NV+ + G +F +D + +
Sbjct: 149 LEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDL 208
Query: 770 QEEG 781
+EG
Sbjct: 209 AQEG 212
>DQ282159-1|ABB77907.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 54.0 bits (124), Expect = 6e-07
Identities = 46/184 (25%), Positives = 80/184 (43%), Gaps = 6/184 (3%)
Frame = +2
Query: 248 PPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSK 427
PPGP LP +G L +D + L + +G ++ L++ VVL+ VR+A
Sbjct: 34 PPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVT 93
Query: 428 --DSFSGRAPLYLTHGLMNG---NGIICAE-GGLWRDQRKLITSWLKSFGMSKHSVSREK 589
+ + R P+ +T L G G+ A G WR+QR+ S L++ G+ K S
Sbjct: 94 HGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKS----- 148
Query: 590 LEKRIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGFKFPPEDKTWQWFRQI 769
LE+ + + S +L ++ NV+ + G +F +D + +
Sbjct: 149 LEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDL 208
Query: 770 QEEG 781
+EG
Sbjct: 209 AQEG 212
>DQ282156-1|ABB77904.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 54.0 bits (124), Expect = 6e-07
Identities = 46/184 (25%), Positives = 80/184 (43%), Gaps = 6/184 (3%)
Frame = +2
Query: 248 PPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSK 427
PPGP LP +G L +D + L + +G ++ L++ VVL+ VR+A
Sbjct: 34 PPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVT 93
Query: 428 --DSFSGRAPLYLTHGLMNG---NGIICAE-GGLWRDQRKLITSWLKSFGMSKHSVSREK 589
+ + R P+ +T L G G+ A G WR+QR+ S L++ G+ K S
Sbjct: 94 HGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKS----- 148
Query: 590 LEKRIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGFKFPPEDKTWQWFRQI 769
LE+ + + S +L ++ NV+ + G +F +D + +
Sbjct: 149 LEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDL 208
Query: 770 QEEG 781
+EG
Sbjct: 209 AQEG 212
>DQ282155-1|ABB77903.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 54.0 bits (124), Expect = 6e-07
Identities = 46/184 (25%), Positives = 80/184 (43%), Gaps = 6/184 (3%)
Frame = +2
Query: 248 PPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSK 427
PPGP LP +G L +D + L + +G ++ L++ VVL+ VR+A
Sbjct: 34 PPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVT 93
Query: 428 --DSFSGRAPLYLTHGLMNG---NGIICAE-GGLWRDQRKLITSWLKSFGMSKHSVSREK 589
+ + R P+ +T L G G+ A G WR+QR+ S L++ G+ K S
Sbjct: 94 HGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKS----- 148
Query: 590 LEKRIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGFKFPPEDKTWQWFRQI 769
LE+ + + S +L ++ NV+ + G +F +D + +
Sbjct: 149 LEQWVTKEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDL 208
Query: 770 QEEG 781
+EG
Sbjct: 209 AQEG 212
>DQ282154-1|ABB77902.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 54.0 bits (124), Expect = 6e-07
Identities = 46/184 (25%), Positives = 80/184 (43%), Gaps = 6/184 (3%)
Frame = +2
Query: 248 PPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSK 427
PPGP LP +G L +D + L + +G ++ L++ VVL+ VR+A
Sbjct: 34 PPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVT 93
Query: 428 --DSFSGRAPLYLTHGLMNG---NGIICAE-GGLWRDQRKLITSWLKSFGMSKHSVSREK 589
+ + R P+ +T L G G+ A G WR+QR+ S L++ G+ K S
Sbjct: 94 HGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKS----- 148
Query: 590 LEKRIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGFKFPPEDKTWQWFRQI 769
LE+ + + S +L ++ NV+ + G +F +D + +
Sbjct: 149 LEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDL 208
Query: 770 QEEG 781
+EG
Sbjct: 209 AQEG 212
>DQ282151-1|ABB77899.1| 496|Homo sapiens cytochrome P450 2D6
protein.
Length = 496
Score = 54.0 bits (124), Expect = 6e-07
Identities = 46/184 (25%), Positives = 80/184 (43%), Gaps = 6/184 (3%)
Frame = +2
Query: 248 PPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSK 427
PPGP LP +G L +D + L + +G ++ L++ VVL+ VR+A
Sbjct: 34 PPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVT 93
Query: 428 --DSFSGRAPLYLTHGLMNG---NGIICAE-GGLWRDQRKLITSWLKSFGMSKHSVSREK 589
+ + R P+ +T L G G+ A G WR+QR+ S L++ G+ K S
Sbjct: 94 HGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKS----- 148
Query: 590 LEKRIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGFKFPPEDKTWQWFRQI 769
LE+ + + S +L ++ NV+ + G +F +D + +
Sbjct: 149 LEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDL 208
Query: 770 QEEG 781
+EG
Sbjct: 209 AQEG 212
>DQ282147-1|ABB77898.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 54.0 bits (124), Expect = 6e-07
Identities = 46/184 (25%), Positives = 80/184 (43%), Gaps = 6/184 (3%)
Frame = +2
Query: 248 PPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSK 427
PPGP LP +G L +D + L + +G ++ L++ VVL+ VR+A
Sbjct: 34 PPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVT 93
Query: 428 --DSFSGRAPLYLTHGLMNG---NGIICAE-GGLWRDQRKLITSWLKSFGMSKHSVSREK 589
+ + R P+ +T L G G+ A G WR+QR+ S L++ G+ K S
Sbjct: 94 HGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKS----- 148
Query: 590 LEKRIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGFKFPPEDKTWQWFRQI 769
LE+ + + S +L ++ NV+ + G +F +D + +
Sbjct: 149 LEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDL 208
Query: 770 QEEG 781
+EG
Sbjct: 209 AQEG 212
>DQ282146-1|ABB77897.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 54.0 bits (124), Expect = 6e-07
Identities = 46/184 (25%), Positives = 80/184 (43%), Gaps = 6/184 (3%)
Frame = +2
Query: 248 PPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSK 427
PPGP LP +G L +D + L + +G ++ L++ VVL+ VR+A
Sbjct: 34 PPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVT 93
Query: 428 --DSFSGRAPLYLTHGLMNG---NGIICAE-GGLWRDQRKLITSWLKSFGMSKHSVSREK 589
+ + R P+ +T L G G+ A G WR+QR+ S L++ G+ K S
Sbjct: 94 HGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKS----- 148
Query: 590 LEKRIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGFKFPPEDKTWQWFRQI 769
LE+ + + S +L ++ NV+ + G +F +D + +
Sbjct: 149 LEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDL 208
Query: 770 QEEG 781
+EG
Sbjct: 209 AQEG 212
>DQ282145-1|ABB77896.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 54.0 bits (124), Expect = 6e-07
Identities = 46/184 (25%), Positives = 80/184 (43%), Gaps = 6/184 (3%)
Frame = +2
Query: 248 PPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSK 427
PPGP LP +G L +D + L + +G ++ L++ VVL+ VR+A
Sbjct: 34 PPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVT 93
Query: 428 --DSFSGRAPLYLTHGLMNG---NGIICAE-GGLWRDQRKLITSWLKSFGMSKHSVSREK 589
+ + R P+ +T L G G+ A G WR+QR+ S L++ G+ K S
Sbjct: 94 HGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKS----- 148
Query: 590 LEKRIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGFKFPPEDKTWQWFRQI 769
LE+ + + S +L ++ NV+ + G +F +D + +
Sbjct: 149 LEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDL 208
Query: 770 QEEG 781
+EG
Sbjct: 209 AQEG 212
>DQ282144-1|ABB77895.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 54.0 bits (124), Expect = 6e-07
Identities = 46/184 (25%), Positives = 80/184 (43%), Gaps = 6/184 (3%)
Frame = +2
Query: 248 PPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSK 427
PPGP LP +G L +D + L + +G ++ L++ VVL+ VR+A
Sbjct: 34 PPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVT 93
Query: 428 --DSFSGRAPLYLTHGLMNG---NGIICAE-GGLWRDQRKLITSWLKSFGMSKHSVSREK 589
+ + R P+ +T L G G+ A G WR+QR+ S L++ G+ K S
Sbjct: 94 HGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKS----- 148
Query: 590 LEKRIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGFKFPPEDKTWQWFRQI 769
LE+ + + S +L ++ NV+ + G +F +D + +
Sbjct: 149 LEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDL 208
Query: 770 QEEG 781
+EG
Sbjct: 209 AQEG 212
>BC126858-1|AAI26859.1| 497|Homo sapiens cytochrome P450, family 2,
subfamily D, polypeptide 6 protein.
Length = 497
Score = 54.0 bits (124), Expect = 6e-07
Identities = 46/184 (25%), Positives = 80/184 (43%), Gaps = 6/184 (3%)
Frame = +2
Query: 248 PPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSK 427
PPGP LP +G L +D + L + +G ++ L++ VVL+ VR+A
Sbjct: 34 PPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVT 93
Query: 428 --DSFSGRAPLYLTHGLMNG---NGIICAE-GGLWRDQRKLITSWLKSFGMSKHSVSREK 589
+ + R P+ +T L G G+ A G WR+QR+ S L++ G+ K S
Sbjct: 94 HGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKS----- 148
Query: 590 LEKRIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGFKFPPEDKTWQWFRQI 769
LE+ + + S +L ++ NV+ + G +F +D + +
Sbjct: 149 LEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDL 208
Query: 770 QEEG 781
+EG
Sbjct: 209 AQEG 212
>BC106758-1|AAI06759.1| 497|Homo sapiens cytochrome P450, family 2,
subfamily D, polypeptide 6 protein.
Length = 497
Score = 54.0 bits (124), Expect = 6e-07
Identities = 46/184 (25%), Positives = 80/184 (43%), Gaps = 6/184 (3%)
Frame = +2
Query: 248 PPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSK 427
PPGP LP +G L +D + L + +G ++ L++ VVL+ VR+A
Sbjct: 34 PPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVT 93
Query: 428 --DSFSGRAPLYLTHGLMNG---NGIICAE-GGLWRDQRKLITSWLKSFGMSKHSVSREK 589
+ + R P+ +T L G G+ A G WR+QR+ S L++ G+ K S
Sbjct: 94 HGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKS----- 148
Query: 590 LEKRIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGFKFPPEDKTWQWFRQI 769
LE+ + + S +L ++ NV+ + G +F +D + +
Sbjct: 149 LEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDL 208
Query: 770 QEEG 781
+EG
Sbjct: 209 AQEG 212
>BC075024-1|AAH75024.1| 497|Homo sapiens cytochrome P450, family 2,
subfamily D, polypeptide 6 protein.
Length = 497
Score = 54.0 bits (124), Expect = 6e-07
Identities = 46/184 (25%), Positives = 80/184 (43%), Gaps = 6/184 (3%)
Frame = +2
Query: 248 PPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSK 427
PPGP LP +G L +D + L + +G ++ L++ VVL+ VR+A
Sbjct: 34 PPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVT 93
Query: 428 --DSFSGRAPLYLTHGLMNG---NGIICAE-GGLWRDQRKLITSWLKSFGMSKHSVSREK 589
+ + R P+ +T L G G+ A G WR+QR+ S L++ G+ K S
Sbjct: 94 HGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKS----- 148
Query: 590 LEKRIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGFKFPPEDKTWQWFRQI 769
LE+ + + S +L ++ NV+ + G +F +D + +
Sbjct: 149 LEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDL 208
Query: 770 QEEG 781
+EG
Sbjct: 209 AQEG 212
>BC075023-1|AAH75023.1| 497|Homo sapiens cytochrome P450, family 2,
subfamily D, polypeptide 6 protein.
Length = 497
Score = 54.0 bits (124), Expect = 6e-07
Identities = 46/184 (25%), Positives = 80/184 (43%), Gaps = 6/184 (3%)
Frame = +2
Query: 248 PPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSK 427
PPGP LP +G L +D + L + +G ++ L++ VVL+ VR+A
Sbjct: 34 PPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVT 93
Query: 428 --DSFSGRAPLYLTHGLMNG---NGIICAE-GGLWRDQRKLITSWLKSFGMSKHSVSREK 589
+ + R P+ +T L G G+ A G WR+QR+ S L++ G+ K S
Sbjct: 94 HGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKS----- 148
Query: 590 LEKRIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGFKFPPEDKTWQWFRQI 769
LE+ + + S +L ++ NV+ + G +F +D + +
Sbjct: 149 LEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDL 208
Query: 770 QEEG 781
+EG
Sbjct: 209 AQEG 212
>BC067432-1|AAH67432.1| 497|Homo sapiens cytochrome P450, family 2,
subfamily D, polypeptide 6 protein.
Length = 497
Score = 54.0 bits (124), Expect = 6e-07
Identities = 46/184 (25%), Positives = 80/184 (43%), Gaps = 6/184 (3%)
Frame = +2
Query: 248 PPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSK 427
PPGP LP +G L +D + L + +G ++ L++ VVL+ VR+A
Sbjct: 34 PPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVT 93
Query: 428 --DSFSGRAPLYLTHGLMNG---NGIICAE-GGLWRDQRKLITSWLKSFGMSKHSVSREK 589
+ + R P+ +T L G G+ A G WR+QR+ S L++ G+ K S
Sbjct: 94 HGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKS----- 148
Query: 590 LEKRIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGFKFPPEDKTWQWFRQI 769
LE+ + + S +L ++ NV+ + G +F +D + +
Sbjct: 149 LEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDL 208
Query: 770 QEEG 781
+EG
Sbjct: 209 AQEG 212
>AY545216-1|AAS55001.1| 497|Homo sapiens cytochrome P4502D6
protein.
Length = 497
Score = 54.0 bits (124), Expect = 6e-07
Identities = 46/184 (25%), Positives = 80/184 (43%), Gaps = 6/184 (3%)
Frame = +2
Query: 248 PPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSK 427
PPGP LP +G L +D + L + +G ++ L++ VVL+ VR+A
Sbjct: 34 PPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVT 93
Query: 428 --DSFSGRAPLYLTHGLMNG---NGIICAE-GGLWRDQRKLITSWLKSFGMSKHSVSREK 589
+ + R P+ +T L G G+ A G WR+QR+ S L++ G+ K S
Sbjct: 94 HGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKS----- 148
Query: 590 LEKRIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGFKFPPEDKTWQWFRQI 769
LE+ + + S +L ++ NV+ + G +F +D + +
Sbjct: 149 LEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDL 208
Query: 770 QEEG 781
+EG
Sbjct: 209 AQEG 212
>DQ282153-1|ABB77901.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 53.6 bits (123), Expect = 8e-07
Identities = 46/184 (25%), Positives = 80/184 (43%), Gaps = 6/184 (3%)
Frame = +2
Query: 248 PPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSK 427
PPGP LP +G L +D + L + +G ++ L++ VVL+ VR+A
Sbjct: 34 PPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVT 93
Query: 428 --DSFSGRAPLYLTHGLMNG---NGIICAE-GGLWRDQRKLITSWLKSFGMSKHSVSREK 589
+ + R P+ +T L G G+ A G WR+QR+ S L++ G+ K S
Sbjct: 94 HGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSISTLRNLGLGKKS----- 148
Query: 590 LEKRIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGFKFPPEDKTWQWFRQI 769
LE+ + + S +L ++ NV+ + G +F +D + +
Sbjct: 149 LEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDL 208
Query: 770 QEEG 781
+EG
Sbjct: 209 AQEG 212
>AY220845-1|AAO49806.1| 516|Homo sapiens cytochrome P450 protein.
Length = 516
Score = 52.8 bits (121), Expect = 1e-06
Identities = 45/184 (24%), Positives = 80/184 (43%), Gaps = 6/184 (3%)
Frame = +2
Query: 248 PPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSK 427
PPGP LP +G L +D + L + +G ++ L++ VVL+ VR+A
Sbjct: 34 PPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFNLQLAWTPVVVLNGLAAVREAMVT 93
Query: 428 --DSFSGR--APLYLTHGL-MNGNGIICAE-GGLWRDQRKLITSWLKSFGMSKHSVSREK 589
+ + R AP+Y G G+I + G WR+QR+ S L++ G+ K S
Sbjct: 94 RGEDTADRPPAPIYQVLGFGPRSQGVILSRYGPAWREQRRFSVSTLRNLGLGKKS----- 148
Query: 590 LEKRIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGFKFPPEDKTWQWFRQI 769
LE+ + + + +L ++ NV+ + G +F +D + +
Sbjct: 149 LEQWVTEEAACLCAAFADQAGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDL 208
Query: 770 QEEG 781
+EG
Sbjct: 209 AQEG 212
>DQ282162-1|ABB77909.1| 500|Homo sapiens cytochrome P450 2D6
protein.
Length = 500
Score = 52.4 bits (120), Expect = 2e-06
Identities = 45/184 (24%), Positives = 81/184 (44%), Gaps = 6/184 (3%)
Frame = +2
Query: 248 PPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSK 427
PPGP LP +G L +D + L + +G ++ L++ VVL+ VR+A
Sbjct: 34 PPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVT 93
Query: 428 --DSFSGRAPLYLTHGLMNG---NGIICAE-GGLWRDQRKLITSWLKSFGMSKHSVSREK 589
+ + R P+ + L G G+ A G WR+QR+ S L++ G+ K S+ +
Sbjct: 94 HGEDTADRPPVPIIQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQWV 153
Query: 590 LEKRIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGFKFPPEDKTWQWFRQI 769
E+ A+ + N +L ++ NV+ + G +F +D + +
Sbjct: 154 TEE--AACLCAAFANHSGRPFRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDL 211
Query: 770 QEEG 781
+EG
Sbjct: 212 AQEG 215
>DQ282158-1|ABB77906.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 51.6 bits (118), Expect = 3e-06
Identities = 45/184 (24%), Positives = 79/184 (42%), Gaps = 6/184 (3%)
Frame = +2
Query: 248 PPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSK 427
PPGP LP +G L +D + L + +G ++ L++ VVL+ VR+A
Sbjct: 34 PPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVT 93
Query: 428 --DSFSGRAPLYLTHGLMNG---NGIICAE-GGLWRDQRKLITSWLKSFGMSKHSVSREK 589
+ + R P+ + L G G+ A G WR+QR+ S L++ G+ K S
Sbjct: 94 HGEDTADRPPVPIIQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKS----- 148
Query: 590 LEKRIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGFKFPPEDKTWQWFRQI 769
LE+ + + S +L ++ NV+ + G +F +D + +
Sbjct: 149 LEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDL 208
Query: 770 QEEG 781
+EG
Sbjct: 209 AQEG 212
>DQ282157-1|ABB77905.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 51.6 bits (118), Expect = 3e-06
Identities = 45/184 (24%), Positives = 79/184 (42%), Gaps = 6/184 (3%)
Frame = +2
Query: 248 PPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSK 427
PPGP LP +G L +D + L + +G ++ L++ VVL+ VR+A
Sbjct: 34 PPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVT 93
Query: 428 --DSFSGRAPLYLTHGLMNG---NGIICAE-GGLWRDQRKLITSWLKSFGMSKHSVSREK 589
+ + R P+ + L G G+ A G WR+QR+ S L++ G+ K S
Sbjct: 94 HGEDTADRPPVPIIQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKS----- 148
Query: 590 LEKRIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGFKFPPEDKTWQWFRQI 769
LE+ + + S +L ++ NV+ + G +F +D + +
Sbjct: 149 LEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDL 208
Query: 770 QEEG 781
+EG
Sbjct: 209 AQEG 212
>DQ282152-1|ABB77900.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 51.2 bits (117), Expect = 4e-06
Identities = 45/183 (24%), Positives = 79/183 (43%), Gaps = 6/183 (3%)
Frame = +2
Query: 251 PGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSK- 427
PGP LP +G L +D + L + +G ++ L++ VVL+ VR+A
Sbjct: 35 PGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVTH 94
Query: 428 -DSFSGRAPLYLTHGLMNG---NGIICAE-GGLWRDQRKLITSWLKSFGMSKHSVSREKL 592
+ + R P+ +T L G G+ A G WR+QR+ S L++ G+ K S L
Sbjct: 95 GEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKS-----L 149
Query: 593 EKRIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGFKFPPEDKTWQWFRQIQ 772
E+ + + S +L ++ NV+ + G +F +D + +
Sbjct: 150 EQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLA 209
Query: 773 EEG 781
+EG
Sbjct: 210 QEG 212
>DQ211354-2|ABB01372.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 51.2 bits (117), Expect = 4e-06
Identities = 45/183 (24%), Positives = 79/183 (43%), Gaps = 6/183 (3%)
Frame = +2
Query: 251 PGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSK- 427
PGP LP +G L +D + L + +G ++ L++ VVL+ VR+A
Sbjct: 35 PGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVTH 94
Query: 428 -DSFSGRAPLYLTHGLMNG---NGIICAE-GGLWRDQRKLITSWLKSFGMSKHSVSREKL 592
+ + R P+ +T L G G+ A G WR+QR+ S L++ G+ K S L
Sbjct: 95 GEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKS-----L 149
Query: 593 EKRIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGFKFPPEDKTWQWFRQIQ 772
E+ + + S +L ++ NV+ + G +F +D + +
Sbjct: 150 EQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLA 209
Query: 773 EEG 781
+EG
Sbjct: 210 QEG 212
>DQ211353-2|ABB01371.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 51.2 bits (117), Expect = 4e-06
Identities = 45/183 (24%), Positives = 79/183 (43%), Gaps = 6/183 (3%)
Frame = +2
Query: 251 PGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSK- 427
PGP LP +G L +D + L + +G ++ L++ VVL+ VR+A
Sbjct: 35 PGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVTH 94
Query: 428 -DSFSGRAPLYLTHGLMNG---NGIICAE-GGLWRDQRKLITSWLKSFGMSKHSVSREKL 592
+ + R P+ +T L G G+ A G WR+QR+ S L++ G+ K S L
Sbjct: 95 GEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKS-----L 149
Query: 593 EKRIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGFKFPPEDKTWQWFRQIQ 772
E+ + + S +L ++ NV+ + G +F +D + +
Sbjct: 150 EQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLA 209
Query: 773 EEG 781
+EG
Sbjct: 210 QEG 212
>DQ211353-1|ABB01370.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 51.2 bits (117), Expect = 4e-06
Identities = 45/183 (24%), Positives = 79/183 (43%), Gaps = 6/183 (3%)
Frame = +2
Query: 251 PGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSK- 427
PGP LP +G L +D + L + +G ++ L++ VVL+ VR+A
Sbjct: 35 PGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVTH 94
Query: 428 -DSFSGRAPLYLTHGLMNG---NGIICAE-GGLWRDQRKLITSWLKSFGMSKHSVSREKL 592
+ + R P+ +T L G G+ A G WR+QR+ S L++ G+ K S L
Sbjct: 95 GEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKS-----L 149
Query: 593 EKRIASGVYEILENIEKTSDAALDLPHMLTNSLGNVVNEIIFGFKFPPEDKTWQWFRQIQ 772
E+ + + S +L ++ NV+ + G +F +D + +
Sbjct: 150 EQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLA 209
Query: 773 EEG 781
+EG
Sbjct: 210 QEG 212
>AY513607-1|AAR90938.1| 100|Homo sapiens truncated cytochrome P450
2A13 variant 4 protein.
Length = 100
Score = 44.4 bits (100), Expect = 5e-04
Identities = 23/78 (29%), Positives = 41/78 (52%), Gaps = 2/78 (2%)
Frame = +2
Query: 215 IFKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLS 394
++++ K LPPGP LP +G ++ + +L +S+ YG ++ + +G VVL
Sbjct: 23 VWRQRKSRGKLPPGPTPLPFIGNYLQLNTEQMYNSLMKISERYGPVFTIHLGPRRVVVLC 82
Query: 395 DHKLVRDAF--SKDSFSG 442
H V++A + FSG
Sbjct: 83 GHDAVKEALVDQAEEFSG 100
>AK000366-1|BAA91114.1| 408|Homo sapiens protein ( Homo sapiens
cDNA FLJ20359 fis, clone HEP16626. ).
Length = 408
Score = 44.4 bits (100), Expect = 5e-04
Identities = 24/92 (26%), Positives = 46/92 (50%), Gaps = 2/92 (2%)
Frame = +2
Query: 329 LSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSK--DSFSGRAPLYLTHGLMNGNGIICAE 502
LS+ YG ++ + +G VVL+ + V++A + + R P+ + + G GI +
Sbjct: 3 LSERYGPVFTVHLGRQKTVVLTGFEAVKEALAGPGQELADRPPIAIFQLIQRGGGIFFSS 62
Query: 503 GGLWRDQRKLITSWLKSFGMSKHSVSREKLEK 598
G WR R+ L S G+ + V+ + L++
Sbjct: 63 GARWRAARQFTVRALHSLGVGREPVADKILQE 94
>DQ372705-1|ABD16216.1| 150|Homo sapiens mutant cytochrome p450
protein.
Length = 150
Score = 42.3 bits (95), Expect = 0.002
Identities = 20/86 (23%), Positives = 49/86 (56%), Gaps = 2/86 (2%)
Frame = +2
Query: 230 KEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLV 409
++ ++ PPGP+ P++G + + H++ L++ YG ++ +++GS VVL+ + +
Sbjct: 45 RQLRSAPPGPFAWPLIGNAAAVGQA-AHLSFARLARRYGDVFQIRLGSCPIVVLNGERAI 103
Query: 410 RDAFSK--DSFSGRAPLYLTHGLMNG 481
A + +F+ R P + + +++G
Sbjct: 104 HQALVQQGSAFADR-PAFASFRVVSG 128
>M21940-1|AAA52159.1| 383|Homo sapiens CYP2C protein.
Length = 383
Score = 41.9 bits (94), Expect = 0.003
Identities = 26/89 (29%), Positives = 45/89 (50%)
Frame = +2
Query: 479 GNGIICAEGGLWRDQRKLITSWLKSFGMSKHSVSREKLEKRIASGVYEILENIEKTSDAA 658
G GI+ + G W++ R+ L++FGM K S+ E R+ ++E + KT +
Sbjct: 2 GFGIVFSNGKKWKEIRRFSLMTLRNFGMGKRSI-----EDRVQEEARCLVEELRKTKASP 56
Query: 659 LDLPHMLTNSLGNVVNEIIFGFKFPPEDK 745
D +L + NV+ IIF +F +D+
Sbjct: 57 CDPTFILGCAPCNVICSIIFHKRFDYKDQ 85
>AF171066-1|AAG43404.1| 112|Homo sapiens CYP1B1 variant protein.
Length = 112
Score = 40.3 bits (90), Expect = 0.008
Identities = 16/57 (28%), Positives = 33/57 (57%)
Frame = +2
Query: 248 PPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDA 418
PPGP+ P++G + + H++ L++ YG ++ +++GS VVL+ + + A
Sbjct: 51 PPGPFAWPLIGNAAAVGQA-AHLSFARLARRYGDVFQIRLGSCPIVVLNGERAIHQA 106
>AB209492-1|BAD92729.1| 566|Homo sapiens Debrisoquine 4-hydroxylase
mutant allele variant protein.
Length = 566
Score = 40.3 bits (90), Expect = 0.008
Identities = 39/157 (24%), Positives = 68/157 (43%), Gaps = 6/157 (3%)
Frame = +2
Query: 329 LSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSK--DSFSGRAPLYLTHGLMNG---NGII 493
L + +G ++ L++ VVL+ VR+A + + R P+ +T L G G+
Sbjct: 131 LRRRFGDVFSLQLAWTPVVVLNGLAAVREAMVTRGEDTADRPPVPITQILGFGPRSQGVF 190
Query: 494 CAE-GGLWRDQRKLITSWLKSFGMSKHSVSREKLEKRIASGVYEILENIEKTSDAALDLP 670
A G WR+QR+ S L++ G+ K S LE+ + + SDA P
Sbjct: 191 LARYGPAWREQRRFSVSTLRNLGLGKKS-----LEQWVTEEAACLCAAFANHSDAPF-AP 244
Query: 671 HMLTNSLGNVVNEIIFGFKFPPEDKTWQWFRQIQEEG 781
+ NV+ + G +F +D + + +EG
Sbjct: 245 TVSWTKPSNVIASLTCGRRFEYDDPRFLRLLDLAQEG 281
>BC012027-1|AAH12027.1| 168|Homo sapiens CYP2U1 protein protein.
Length = 168
Score = 35.1 bits (77), Expect = 0.29
Identities = 18/48 (37%), Positives = 28/48 (58%), Gaps = 2/48 (4%)
Frame = +2
Query: 308 PHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSKDS--FSGR 445
P + L +L++ YG+I+ +G VVLSD VR+A + + FS R
Sbjct: 103 PQVLLAHLARVYGSIFSFFIGHYLVVVLSDFHSVREALVQQAEVFSDR 150
>BC109084-1|AAI09085.1| 448|Homo sapiens CYP24A1 protein protein.
Length = 448
Score = 31.5 bits (68), Expect = 3.6
Identities = 21/65 (32%), Positives = 30/65 (46%), Gaps = 4/65 (6%)
Frame = +2
Query: 251 PGPWGLPIVGYLPFI----DRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDA 418
PGP P++G L I H TL K YG I+ +K+GS +V L L+
Sbjct: 59 PGPTSWPLLGSLLQILWKGGLKKQHDTLVEYHKKYGKIFRMKLGSFESVHLGSPCLLEAL 118
Query: 419 FSKDS 433
+ +S
Sbjct: 119 YRTES 123
>BC109083-1|AAI09084.1| 448|Homo sapiens CYP24A1 protein protein.
Length = 448
Score = 31.5 bits (68), Expect = 3.6
Identities = 21/65 (32%), Positives = 30/65 (46%), Gaps = 4/65 (6%)
Frame = +2
Query: 251 PGPWGLPIVGYLPFI----DRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDA 418
PGP P++G L I H TL K YG I+ +K+GS +V L L+
Sbjct: 59 PGPTSWPLLGSLLQILWKGGLKKQHDTLVEYHKKYGKIFRMKLGSFESVHLGSPCLLEAL 118
Query: 419 FSKDS 433
+ +S
Sbjct: 119 YRTES 123
>AL138805-3|CAM27343.1| 448|Homo sapiens cytochrome P450, family
24, subfamily A, polypeptide 1 protein.
Length = 448
Score = 31.5 bits (68), Expect = 3.6
Identities = 21/65 (32%), Positives = 30/65 (46%), Gaps = 4/65 (6%)
Frame = +2
Query: 251 PGPWGLPIVGYLPFI----DRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDA 418
PGP P++G L I H TL K YG I+ +K+GS +V L L+
Sbjct: 59 PGPTSWPLLGSLLQILWKGGLKKQHDTLVEYHKKYGKIFRMKLGSFESVHLGSPCLLEAL 118
Query: 419 FSKDS 433
+ +S
Sbjct: 119 YRTES 123
>AL138805-2|CAB91829.1| 514|Homo sapiens cytochrome P450, family
24, subfamily A, polypeptide 1 protein.
Length = 514
Score = 31.5 bits (68), Expect = 3.6
Identities = 21/65 (32%), Positives = 30/65 (46%), Gaps = 4/65 (6%)
Frame = +2
Query: 251 PGPWGLPIVGYLPFI----DRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDA 418
PGP P++G L I H TL K YG I+ +K+GS +V L L+
Sbjct: 59 PGPTSWPLLGSLLQILWKGGLKKQHDTLVEYHKKYGKIFRMKLGSFESVHLGSPCLLEAL 118
Query: 419 FSKDS 433
+ +S
Sbjct: 119 YRTES 123
>M61858-1|AAA52145.1| 370|Homo sapiens CYP2C17 protein.
Length = 370
Score = 31.1 bits (67), Expect = 4.8
Identities = 21/77 (27%), Positives = 39/77 (50%)
Frame = +2
Query: 515 RDQRKLITSWLKSFGMSKHSVSREKLEKRIASGVYEILENIEKTSDAALDLPHMLTNSLG 694
++ R+ L++FGM K S+ E R+ ++E + KT+ + D +L +
Sbjct: 1 KEIRRFCLITLRNFGMGKRSI-----EDRVQEEARCLVEELRKTNASPCDPTFILGCAPC 55
Query: 695 NVVNEIIFGFKFPPEDK 745
NV+ IIF +F +D+
Sbjct: 56 NVICSIIFHKRFDYKDQ 72
>L13286-1|AAA62379.1| 513|Homo sapiens 1,25-dihydroxyvitamin D3
24-hydroxylase protein.
Length = 513
Score = 31.1 bits (67), Expect = 4.8
Identities = 27/100 (27%), Positives = 41/100 (41%), Gaps = 8/100 (8%)
Frame = +2
Query: 251 PGPWGLPIVGYLPFI----DRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDA 418
PGP P++ L I H TL K YG I+ +K+GS +V L L+
Sbjct: 59 PGPTSWPLLASLLQILWKGGLKKQHDTLVEYHKKYGKIFRMKLGSFESVHLGSPCLLEAL 118
Query: 419 FSKDSFSGRAPLYLTHGLMN----GNGIICAEGGLWRDQR 526
+ +S R + + G G++ EG W+ R
Sbjct: 119 YRTESVPQRLEIKPWKAYRDYRKEGYGLLILEGEDWQRVR 158
>BC036233-1|AAH36233.1| 946|Homo sapiens WDR66 protein protein.
Length = 946
Score = 31.1 bits (67), Expect = 4.8
Identities = 10/23 (43%), Positives = 17/23 (73%), Gaps = 2/23 (8%)
Frame = -2
Query: 525 LWSLHKPPS--AQIIPFPFIRPC 463
+W +H+PPS + + FP+I+PC
Sbjct: 477 VWDIHRPPSSASTFLGFPYIKPC 499
>BC028421-1|AAH28421.1| 1154|Homo sapiens WD repeat domain 66
protein.
Length = 1154
Score = 31.1 bits (67), Expect = 4.8
Identities = 10/23 (43%), Positives = 17/23 (73%), Gaps = 2/23 (8%)
Frame = -2
Query: 525 LWSLHKPPS--AQIIPFPFIRPC 463
+W +H+PPS + + FP+I+PC
Sbjct: 477 VWDIHRPPSSASTFLGFPYIKPC 499
>EF122245-1|ABO41980.1| 54|Homo sapiens cytochrome P450 2F1
variant protein.
Length = 54
Score = 30.7 bits (66), Expect = 6.3
Identities = 16/40 (40%), Positives = 25/40 (62%), Gaps = 2/40 (5%)
Frame = +2
Query: 329 LSKTYGAIYGLKMGSIYAVVLSDHKLVRDAF--SKDSFSG 442
LSK YG++Y + +G VVLS ++ V++A + FSG
Sbjct: 1 LSKEYGSMYTVHLGPRRVVVLSGYQAVKEALVDQGEEFSG 40
>BX538127-1|CAD98029.1| 310|Homo sapiens hypothetical protein
protein.
Length = 310
Score = 30.7 bits (66), Expect = 6.3
Identities = 20/74 (27%), Positives = 37/74 (50%)
Frame = +2
Query: 524 RKLITSWLKSFGMSKHSVSREKLEKRIASGVYEILENIEKTSDAALDLPHMLTNSLGNVV 703
R+ L++FGM K S+ E R+ ++E + KT+ + D +L + NV+
Sbjct: 3 RRFCLMTLRNFGMGKRSI-----EDRVQEEARCLVEELRKTNASPCDPAFILGCAPCNVI 57
Query: 704 NEIIFGFKFPPEDK 745
+IF +F +D+
Sbjct: 58 CSVIFHDRFDYKDQ 71
>X58908-1|CAA41711.1| 97|Homo sapiens steroid 21-monooxygenase
protein.
Length = 97
Score = 30.3 bits (65), Expect = 8.4
Identities = 28/96 (29%), Positives = 45/96 (46%), Gaps = 5/96 (5%)
Frame = +2
Query: 173 LYFIWLVTFVAG---FWIFKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTY 343
L + L+ +AG W + K++ LP P G+L + P I L L++ +
Sbjct: 4 LGLLLLLPLLAGARLLWNWWKLRSLHLLPLAP------GFLHLLQPDLP-IYLLGLTQKF 56
Query: 344 GAIYGLKMGSIYAVVLSDHKLVRDAFSKD--SFSGR 445
G IY L +G VVL+ + + +A K F+GR
Sbjct: 57 GPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGR 92
>BC024324-1|AAH24324.1| 440|Homo sapiens TNRC6A protein protein.
Length = 440
Score = 30.3 bits (65), Expect = 8.4
Identities = 12/29 (41%), Positives = 18/29 (62%)
Frame = +3
Query: 696 TLSMR*YSALSFHLKIKHGNGFVKYRRKD 782
TL M+ ++FHL + HGN V+Y K+
Sbjct: 277 TLCMQHGPLITFHLNLPHGNALVRYSSKE 305
>AY035864-1|AAK62026.1| 1709|Homo sapiens GW182 autoantigen protein.
Length = 1709
Score = 30.3 bits (65), Expect = 8.4
Identities = 12/29 (41%), Positives = 18/29 (62%)
Frame = +3
Query: 696 TLSMR*YSALSFHLKIKHGNGFVKYRRKD 782
TL M+ ++FHL + HGN V+Y K+
Sbjct: 1546 TLCMQHGPLITFHLNLPHGNALVRYSSKE 1574
>AK001773-1|BAA91899.1| 440|Homo sapiens protein ( Homo sapiens
cDNA FLJ10911 fis, clone OVARC1000148. ).
Length = 440
Score = 30.3 bits (65), Expect = 8.4
Identities = 12/29 (41%), Positives = 18/29 (62%)
Frame = +3
Query: 696 TLSMR*YSALSFHLKIKHGNGFVKYRRKD 782
TL M+ ++FHL + HGN V+Y K+
Sbjct: 277 TLCMQHGPLITFHLNLPHGNALVRYSSKE 305
>AJ492221-1|CAD37348.1| 1962|Homo sapiens EDIE protein protein.
Length = 1962
Score = 30.3 bits (65), Expect = 8.4
Identities = 12/29 (41%), Positives = 18/29 (62%)
Frame = +3
Query: 696 TLSMR*YSALSFHLKIKHGNGFVKYRRKD 782
TL M+ ++FHL + HGN V+Y K+
Sbjct: 1799 TLCMQHGPLITFHLNLPHGNALVRYSSKE 1827
>AB040893-1|BAA95984.1| 1400|Homo sapiens KIAA1460 protein protein.
Length = 1400
Score = 30.3 bits (65), Expect = 8.4
Identities = 12/29 (41%), Positives = 18/29 (62%)
Frame = +3
Query: 696 TLSMR*YSALSFHLKIKHGNGFVKYRRKD 782
TL M+ ++FHL + HGN V+Y K+
Sbjct: 1237 TLCMQHGPLITFHLNLPHGNALVRYSSKE 1265
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 126,928,352
Number of Sequences: 237096
Number of extensions: 2958201
Number of successful extensions: 9492
Number of sequences better than 10.0: 188
Number of HSP's better than 10.0 without gapping: 9039
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 9247
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 9757565650
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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