Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P14_F_F09
(661 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC014508-1|AAH14508.1| 179|Homo sapiens SEC11 homolog A (S. cer... 307 2e-83
BC000359-1|AAH00359.3| 179|Homo sapiens SEC11 homolog A (S. cer... 307 2e-83
AF061737-1|AAD17526.1| 179|Homo sapiens microsomal signal pepti... 307 2e-83
CR457127-1|CAG33408.1| 179|Homo sapiens SPC18 protein. 306 5e-83
AK223224-1|BAD96944.1| 179|Homo sapiens signal peptidase comple... 306 5e-83
AF108945-1|AAD19640.1| 179|Homo sapiens signal peptidase 18 kDa... 306 5e-83
BC009703-1|AAH09703.1| 192|Homo sapiens SEC11 homolog C (S. cer... 301 1e-81
AF212233-1|AAK14919.1| 192|Homo sapiens microsomal signal pepti... 301 1e-81
AF090315-1|AAC36354.1| 167|Homo sapiens signal peptidase comple... 295 7e-80
AF087906-1|AAP97204.1| 188|Homo sapiens signal peptidase comple... 287 3e-77
AF147791-1|AAD55679.1| 957|Homo sapiens mucin 11 protein. 32 1.6
>BC014508-1|AAH14508.1| 179|Homo sapiens SEC11 homolog A (S.
cerevisiae) protein.
Length = 179
Score = 307 bits (754), Expect = 2e-83
Identities = 141/172 (81%), Positives = 158/172 (91%)
Frame = +2
Query: 131 DDVRRMNKRQFMYQVLSFGMIVSSALMIWKGLMVVTGSESPIVVVLSGSMEPAFHRGDLL 310
DDVRRMNKRQ YQVL+FGMIVSSALMIWKGLMV+TGSESPIVVVLSGSMEPAFHRGDLL
Sbjct: 8 DDVRRMNKRQLYYQVLNFGMIVSSALMIWKGLMVITGSESPIVVVLSGSMEPAFHRGDLL 67
Query: 311 FLTNYPEEPVRVGEIVVFKVEGRDIPIVHRVLKLHEKNNGTVKFLTKGDNNSVDDRGLYA 490
FLTN E+P+RVGEIVVF++EGR+IPIVHRVLK+HEK NG +KFLTKGDNN+VDDRGLY
Sbjct: 68 FLTNRVEDPIRVGEIVVFRIEGREIPIVHRVLKIHEKQNGHIKFLTKGDNNAVDDRGLYK 127
Query: 491 QGQLWLTKKDVVGRARGFLPYVGMVTIYMNEYPKFKFAVLACLAIYVLXHRE 646
QGQ WL KKDVVGRARGF+PY+G+VTI MN+YPKFK+AVL L ++VL HRE
Sbjct: 128 QGQHWLEKKDVVGRARGFVPYIGIVTILMNDYPKFKYAVLFLLGLFVLVHRE 179
>BC000359-1|AAH00359.3| 179|Homo sapiens SEC11 homolog A (S.
cerevisiae) protein.
Length = 179
Score = 307 bits (754), Expect = 2e-83
Identities = 141/172 (81%), Positives = 158/172 (91%)
Frame = +2
Query: 131 DDVRRMNKRQFMYQVLSFGMIVSSALMIWKGLMVVTGSESPIVVVLSGSMEPAFHRGDLL 310
DDVRRMNKRQ YQVL+FGMIVSSALMIWKGLMV+TGSESPIVVVLSGSMEPAFHRGDLL
Sbjct: 8 DDVRRMNKRQLYYQVLNFGMIVSSALMIWKGLMVITGSESPIVVVLSGSMEPAFHRGDLL 67
Query: 311 FLTNYPEEPVRVGEIVVFKVEGRDIPIVHRVLKLHEKNNGTVKFLTKGDNNSVDDRGLYA 490
FLTN E+P+RVGEIVVF++EGR+IPIVHRVLK+HEK NG +KFLTKGDNN+VDDRGLY
Sbjct: 68 FLTNRVEDPIRVGEIVVFRIEGREIPIVHRVLKIHEKQNGHIKFLTKGDNNAVDDRGLYK 127
Query: 491 QGQLWLTKKDVVGRARGFLPYVGMVTIYMNEYPKFKFAVLACLAIYVLXHRE 646
QGQ WL KKDVVGRARGF+PY+G+VTI MN+YPKFK+AVL L ++VL HRE
Sbjct: 128 QGQHWLEKKDVVGRARGFVPYIGIVTILMNDYPKFKYAVLFLLGLFVLVHRE 179
>AF061737-1|AAD17526.1| 179|Homo sapiens microsomal signal
peptidase protein.
Length = 179
Score = 307 bits (754), Expect = 2e-83
Identities = 141/172 (81%), Positives = 158/172 (91%)
Frame = +2
Query: 131 DDVRRMNKRQFMYQVLSFGMIVSSALMIWKGLMVVTGSESPIVVVLSGSMEPAFHRGDLL 310
DDVRRMNKRQ YQVL+FGMIVSSALMIWKGLMV+TGSESPIVVVLSGSMEPAFHRGDLL
Sbjct: 8 DDVRRMNKRQLYYQVLNFGMIVSSALMIWKGLMVITGSESPIVVVLSGSMEPAFHRGDLL 67
Query: 311 FLTNYPEEPVRVGEIVVFKVEGRDIPIVHRVLKLHEKNNGTVKFLTKGDNNSVDDRGLYA 490
FLTN E+P+RVGEIVVF++EGR+IPIVHRVLK+HEK NG +KFLTKGDNN+VDDRGLY
Sbjct: 68 FLTNRVEDPIRVGEIVVFRIEGREIPIVHRVLKIHEKQNGHIKFLTKGDNNAVDDRGLYK 127
Query: 491 QGQLWLTKKDVVGRARGFLPYVGMVTIYMNEYPKFKFAVLACLAIYVLXHRE 646
QGQ WL KKDVVGRARGF+PY+G+VTI MN+YPKFK+AVL L ++VL HRE
Sbjct: 128 QGQHWLEKKDVVGRARGFVPYIGIVTILMNDYPKFKYAVLFLLGLFVLVHRE 179
>CR457127-1|CAG33408.1| 179|Homo sapiens SPC18 protein.
Length = 179
Score = 306 bits (751), Expect = 5e-83
Identities = 140/172 (81%), Positives = 158/172 (91%)
Frame = +2
Query: 131 DDVRRMNKRQFMYQVLSFGMIVSSALMIWKGLMVVTGSESPIVVVLSGSMEPAFHRGDLL 310
DDVRRMNKRQ YQVL+FGMIVSSALMIWKGLMV+TGSESPIVVVLSGSMEPAFHRGDLL
Sbjct: 8 DDVRRMNKRQLYYQVLNFGMIVSSALMIWKGLMVITGSESPIVVVLSGSMEPAFHRGDLL 67
Query: 311 FLTNYPEEPVRVGEIVVFKVEGRDIPIVHRVLKLHEKNNGTVKFLTKGDNNSVDDRGLYA 490
FLTN E+P+RVGEIVVF++EGR+IPIVHRVLK+HEK NG +KFLTKGDNN+VDDRGLY
Sbjct: 68 FLTNRVEDPIRVGEIVVFRIEGREIPIVHRVLKIHEKQNGHIKFLTKGDNNAVDDRGLYK 127
Query: 491 QGQLWLTKKDVVGRARGFLPYVGMVTIYMNEYPKFKFAVLACLAIYVLXHRE 646
QGQ WL KKDVVGRARGF+PY+G+VTI MN+YPKFK+AVL L ++VL HR+
Sbjct: 128 QGQHWLEKKDVVGRARGFVPYIGIVTILMNDYPKFKYAVLFLLGLFVLVHRD 179
>AK223224-1|BAD96944.1| 179|Homo sapiens signal peptidase complex
(18kD) variant protein.
Length = 179
Score = 306 bits (751), Expect = 5e-83
Identities = 141/172 (81%), Positives = 157/172 (91%)
Frame = +2
Query: 131 DDVRRMNKRQFMYQVLSFGMIVSSALMIWKGLMVVTGSESPIVVVLSGSMEPAFHRGDLL 310
DDVRRMNKRQ YQVL+FGMIVSSALMIWKGLMV TGSESPIVVVLSGSMEPAFHRGDLL
Sbjct: 8 DDVRRMNKRQLYYQVLNFGMIVSSALMIWKGLMVTTGSESPIVVVLSGSMEPAFHRGDLL 67
Query: 311 FLTNYPEEPVRVGEIVVFKVEGRDIPIVHRVLKLHEKNNGTVKFLTKGDNNSVDDRGLYA 490
FLTN E+P+RVGEIVVF++EGR+IPIVHRVLK+HEK NG +KFLTKGDNN+VDDRGLY
Sbjct: 68 FLTNRVEDPIRVGEIVVFRIEGREIPIVHRVLKIHEKQNGHIKFLTKGDNNAVDDRGLYK 127
Query: 491 QGQLWLTKKDVVGRARGFLPYVGMVTIYMNEYPKFKFAVLACLAIYVLXHRE 646
QGQ WL KKDVVGRARGF+PY+G+VTI MN+YPKFK+AVL L ++VL HRE
Sbjct: 128 QGQHWLEKKDVVGRARGFVPYIGIVTILMNDYPKFKYAVLFLLGLFVLVHRE 179
>AF108945-1|AAD19640.1| 179|Homo sapiens signal peptidase 18 kDa
subunit protein.
Length = 179
Score = 306 bits (751), Expect = 5e-83
Identities = 140/172 (81%), Positives = 158/172 (91%)
Frame = +2
Query: 131 DDVRRMNKRQFMYQVLSFGMIVSSALMIWKGLMVVTGSESPIVVVLSGSMEPAFHRGDLL 310
DDVRRMNKRQ YQVL+FGMIVSSALMIWKGLMV+TGSESPIVVVLSGSMEPAFHRGDLL
Sbjct: 8 DDVRRMNKRQLCYQVLNFGMIVSSALMIWKGLMVITGSESPIVVVLSGSMEPAFHRGDLL 67
Query: 311 FLTNYPEEPVRVGEIVVFKVEGRDIPIVHRVLKLHEKNNGTVKFLTKGDNNSVDDRGLYA 490
FLTN E+P+RVGEIVVF++EGR+IPIVHRVLK+HEK NG +KFLTKGDNN+VDDRGLY
Sbjct: 68 FLTNRVEDPIRVGEIVVFRIEGREIPIVHRVLKIHEKQNGHIKFLTKGDNNAVDDRGLYK 127
Query: 491 QGQLWLTKKDVVGRARGFLPYVGMVTIYMNEYPKFKFAVLACLAIYVLXHRE 646
QGQ WL KKDVVGRARGF+PY+G+VTI MN+YPKF++AVL L ++VL HRE
Sbjct: 128 QGQHWLEKKDVVGRARGFVPYIGIVTILMNDYPKFRYAVLFLLGLFVLVHRE 179
>BC009703-1|AAH09703.1| 192|Homo sapiens SEC11 homolog C (S.
cerevisiae) protein.
Length = 192
Score = 301 bits (739), Expect = 1e-81
Identities = 138/174 (79%), Positives = 157/174 (90%)
Frame = +2
Query: 125 LFDDVRRMNKRQFMYQVLSFGMIVSSALMIWKGLMVVTGSESPIVVVLSGSMEPAFHRGD 304
+F D+++MNKRQ YQVL+F MIVSSALMIWKGL+V+TGSESPIVVVLSGSMEPAFHRGD
Sbjct: 18 IFGDLKKMNKRQLYYQVLNFAMIVSSALMIWKGLIVLTGSESPIVVVLSGSMEPAFHRGD 77
Query: 305 LLFLTNYPEEPVRVGEIVVFKVEGRDIPIVHRVLKLHEKNNGTVKFLTKGDNNSVDDRGL 484
LLFLTN+ E+P+R GEIVVFKVEGRDIPIVHRV+K+HEK+NG +KFLTKGDNN VDDRGL
Sbjct: 78 LLFLTNFREDPIRAGEIVVFKVEGRDIPIVHRVIKVHEKDNGDIKFLTKGDNNEVDDRGL 137
Query: 485 YAQGQLWLTKKDVVGRARGFLPYVGMVTIYMNEYPKFKFAVLACLAIYVLXHRE 646
Y +GQ WL KKDVVGRARGFLPYVGMVTI MN+YPKFK+A+LA + YVL RE
Sbjct: 138 YKEGQNWLEKKDVVGRARGFLPYVGMVTIIMNDYPKFKYALLAVMGAYVLLKRE 191
>AF212233-1|AAK14919.1| 192|Homo sapiens microsomal signal
peptidase subunit protein.
Length = 192
Score = 301 bits (739), Expect = 1e-81
Identities = 138/174 (79%), Positives = 157/174 (90%)
Frame = +2
Query: 125 LFDDVRRMNKRQFMYQVLSFGMIVSSALMIWKGLMVVTGSESPIVVVLSGSMEPAFHRGD 304
+F D+++MNKRQ YQVL+F MIVSSALMIWKGL+V+TGSESPIVVVLSGSMEPAFHRGD
Sbjct: 18 IFGDLKKMNKRQLYYQVLNFAMIVSSALMIWKGLIVLTGSESPIVVVLSGSMEPAFHRGD 77
Query: 305 LLFLTNYPEEPVRVGEIVVFKVEGRDIPIVHRVLKLHEKNNGTVKFLTKGDNNSVDDRGL 484
LLFLTN+ E+P+R GEIVVFKVEGRDIPIVHRV+K+HEK+NG +KFLTKGDNN VDDRGL
Sbjct: 78 LLFLTNFREDPIRAGEIVVFKVEGRDIPIVHRVIKVHEKDNGDIKFLTKGDNNEVDDRGL 137
Query: 485 YAQGQLWLTKKDVVGRARGFLPYVGMVTIYMNEYPKFKFAVLACLAIYVLXHRE 646
Y +GQ WL KKDVVGRARGFLPYVGMVTI MN+YPKFK+A+LA + YVL RE
Sbjct: 138 YKEGQNWLEKKDVVGRARGFLPYVGMVTIIMNDYPKFKYALLAVMGAYVLLKRE 191
>AF090315-1|AAC36354.1| 167|Homo sapiens signal peptidase complex
18 kDa subunit protein.
Length = 167
Score = 295 bits (725), Expect = 7e-80
Identities = 135/167 (80%), Positives = 153/167 (91%)
Frame = +2
Query: 146 MNKRQFMYQVLSFGMIVSSALMIWKGLMVVTGSESPIVVVLSGSMEPAFHRGDLLFLTNY 325
MNKRQ YQVL+FGMIVSSALMIWKGLMV+TGSESPIVVVLSGSMEPAFHRGDLLFLTN
Sbjct: 1 MNKRQLCYQVLNFGMIVSSALMIWKGLMVITGSESPIVVVLSGSMEPAFHRGDLLFLTNR 60
Query: 326 PEEPVRVGEIVVFKVEGRDIPIVHRVLKLHEKNNGTVKFLTKGDNNSVDDRGLYAQGQLW 505
E+P+RVGEIVVF++EGR+IPIVHRVLK+HEK NG +KFLTKGDNN+VDDRGLY QGQ W
Sbjct: 61 VEDPIRVGEIVVFRIEGREIPIVHRVLKIHEKQNGHIKFLTKGDNNAVDDRGLYKQGQHW 120
Query: 506 LTKKDVVGRARGFLPYVGMVTIYMNEYPKFKFAVLACLAIYVLXHRE 646
L KKDVVGRARGF+PY+G+VTI MN+YPKF++AVL L ++VL HRE
Sbjct: 121 LEKKDVVGRARGFVPYIGIVTILMNDYPKFRYAVLFLLGLFVLVHRE 167
>AF087906-1|AAP97204.1| 188|Homo sapiens signal peptidase complex
SPC-18 protein.
Length = 188
Score = 287 bits (703), Expect = 3e-77
Identities = 131/160 (81%), Positives = 148/160 (92%)
Frame = +2
Query: 167 YQVLSFGMIVSSALMIWKGLMVVTGSESPIVVVLSGSMEPAFHRGDLLFLTNYPEEPVRV 346
YQVL+FGMIVSSALMIWKGLMV+TGSESPIVVVLSGSMEPAFHRGDLLFLTN E+P+RV
Sbjct: 29 YQVLNFGMIVSSALMIWKGLMVITGSESPIVVVLSGSMEPAFHRGDLLFLTNRVEDPIRV 88
Query: 347 GEIVVFKVEGRDIPIVHRVLKLHEKNNGTVKFLTKGDNNSVDDRGLYAQGQLWLTKKDVV 526
GEIVVF++EGR+IPIVHRVLK+HEK NG +KFLTKGDNN+VDDRGLY QGQ WL KKDVV
Sbjct: 89 GEIVVFRIEGREIPIVHRVLKIHEKQNGHIKFLTKGDNNAVDDRGLYKQGQHWLEKKDVV 148
Query: 527 GRARGFLPYVGMVTIYMNEYPKFKFAVLACLAIYVLXHRE 646
GRARGF+PY+G+VTI MN+YPKFK+AVL L ++VL HRE
Sbjct: 149 GRARGFVPYIGIVTILMNDYPKFKYAVLFLLGLFVLVHRE 188
>AF147791-1|AAD55679.1| 957|Homo sapiens mucin 11 protein.
Length = 957
Score = 32.3 bits (70), Expect = 1.6
Identities = 24/55 (43%), Positives = 30/55 (54%), Gaps = 4/55 (7%)
Frame = -2
Query: 381 SRPSTLKTTISPTRTGSSG*LVKNSKSPL*KAGSI----LPDSTTTIGLSLPVTT 229
S P + TT+SP T SSG + + S + + GS PDSTTT GLS TT
Sbjct: 329 SSPRSPATTLSPASTTSSG-VSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTT 382
Score = 30.3 bits (65), Expect = 6.4
Identities = 24/73 (32%), Positives = 34/73 (46%), Gaps = 3/73 (4%)
Frame = -2
Query: 381 SRPSTLKTTISPTRTGSSG*LVKNSKS---PL*KAGSILPDSTTTIGLSLPVTTIKPFHI 211
S P + TT+SP S G +++ S P ++ P STTT GLS TT+
Sbjct: 607 SSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSP 666
Query: 210 IKAEDTIIPKLNT 172
E T+ P+ T
Sbjct: 667 GSTETTVFPRSTT 679
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 101,938,216
Number of Sequences: 237096
Number of extensions: 2185420
Number of successful extensions: 8108
Number of sequences better than 10.0: 11
Number of HSP's better than 10.0 without gapping: 7882
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 8107
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 7422585720
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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