Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P13_pT_J12
(622 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
CR542203-1|CAG47000.1| 316|Homo sapiens AKR1B1 protein. 145 1e-34
X15414-1|CAA33460.1| 316|Homo sapiens protein ( Human mRNA for ... 143 4e-34
M59783-1|AAA51712.1| 316|Homo sapiens aldose reductase protein. 143 4e-34
M34720-1|AAA35560.1| 316|Homo sapiens protein ( Human aldose re... 143 4e-34
J05474-1|AAA51715.1| 316|Homo sapiens aldose reductase protein. 143 4e-34
J05017-1|AAA51714.1| 316|Homo sapiens ALDR1 protein. 143 4e-34
J04795-1|AAA51713.1| 316|Homo sapiens ALDR1 protein. 143 4e-34
CR450351-1|CAG29347.1| 316|Homo sapiens AKR1B1 protein. 143 4e-34
BT019859-1|AAV38662.1| 316|Homo sapiens aldo-keto reductase fam... 143 4e-34
BC010391-1|AAH10391.1| 316|Homo sapiens aldo-keto reductase fam... 143 4e-34
BC000260-1|AAH00260.1| 316|Homo sapiens aldo-keto reductase fam... 143 4e-34
AF328729-1|AAN09721.1| 316|Homo sapiens CTCL tumor antigen HD-C... 143 4e-34
AF032455-1|AAB88851.1| 316|Homo sapiens aldose reductase protein. 143 4e-34
U05861-1|AAA18115.1| 323|Homo sapiens hepatic dihydrodiol dehyd... 142 7e-34
U05684-1|AAA16227.1| 323|Homo sapiens dihydrodiol dehydrogenase... 142 7e-34
M86609-1|AAB02880.1| 323|Homo sapiens dihydrodiol dehydrogenase... 142 7e-34
D26124-1|BAA05121.1| 306|Homo sapiens dihydrodiol dehydrogenase... 142 7e-34
BT007197-1|AAP35861.1| 323|Homo sapiens aldo-keto reductase fam... 142 7e-34
BC040210-1|AAH40210.1| 323|Homo sapiens aldo-keto reductase fam... 142 7e-34
BC020216-1|AAH20216.1| 323|Homo sapiens aldo-keto reductase fam... 142 7e-34
BC015490-1|AAH15490.1| 323|Homo sapiens aldo-keto reductase fam... 142 7e-34
AL713867-2|CAI16409.1| 323|Homo sapiens aldo-keto reductase fam... 142 7e-34
AB032150-1|BAA92886.1| 323|Homo sapiens 20 alph-hydroxysteroid ... 142 7e-34
AB031083-1|BAA92883.1| 323|Homo sapiens 20 alpha-hydroxysteroid... 142 7e-34
Z28339-1|CAA82193.1| 326|Homo sapiens delta 4-3-oxosteroid 5 be... 142 1e-33
BC130627-1|AAI30628.1| 326|Homo sapiens aldo-keto reductase fam... 142 1e-33
BC130625-1|AAI30626.1| 326|Homo sapiens aldo-keto reductase fam... 142 1e-33
AF283659-1|AAG39381.1| 326|Homo sapiens 5-beta steroid reductas... 142 1e-33
S68287-1|AAD14010.1| 323|Homo sapiens chlordecone reductase pro... 141 2e-33
M33375-1|AAA35658.1| 308|Homo sapiens protein ( Human chlordeco... 141 2e-33
D26125-1|BAA05122.1| 321|Homo sapiens 3 alpha-hydroxysteroid/di... 141 2e-33
AB045829-1|BAA99542.1| 323|Homo sapiens 3alpha-hydroxysteroid d... 141 2e-33
AB032163-1|BAA92893.1| 323|Homo sapiens dihydrodiol dehydrogena... 141 2e-33
AB031085-1|BAA92885.1| 323|Homo sapiens dihydrodiol dehydrogena... 141 2e-33
U05598-1|AAA20937.1| 323|Homo sapiens dihydrodiol dehydrogenase... 141 2e-33
S68330-1|AAD14013.1| 323|Homo sapiens chlordecone reductase hom... 141 2e-33
L32592-1|AAB38486.1| 323|Homo sapiens dihydrodiol dehydrogenase... 141 2e-33
BT006653-1|AAP35299.1| 323|Homo sapiens aldo-keto reductase fam... 141 2e-33
BC063574-1|AAH63574.1| 323|Homo sapiens aldo-keto reductase fam... 141 2e-33
BC007024-1|AAH07024.1| 323|Homo sapiens aldo-keto reductase fam... 141 2e-33
AL713867-1|CAI16408.1| 323|Homo sapiens aldo-keto reductase fam... 141 2e-33
AL391427-1|CAI14726.1| 323|Homo sapiens aldo-keto reductase fam... 141 2e-33
AL355303-2|CAI14202.1| 323|Homo sapiens aldo-keto reductase fam... 141 2e-33
AB032153-1|BAA92891.1| 323|Homo sapiens bile acid-binding prote... 141 2e-33
AB031084-1|BAA92884.1| 323|Homo sapiens bile acid-binding prote... 141 2e-33
AB021654-1|BAA36169.1| 323|Homo sapiens DD2/bile acid-binding p... 141 2e-33
S68290-1|AAD14012.1| 320|Homo sapiens chlordecone reductase hom... 140 3e-33
BC020744-1|AAH20744.1| 323|Homo sapiens aldo-keto reductase fam... 140 3e-33
J04794-1|AAA51711.1| 325|Homo sapiens ALDR1 protein. 138 1e-32
CR457010-1|CAG33291.1| 325|Homo sapiens AKR1A1 protein. 138 1e-32
BT007003-1|AAP35649.1| 325|Homo sapiens aldo-keto reductase fam... 138 1e-32
BC005394-1|AAH05394.1| 325|Homo sapiens aldo-keto reductase fam... 138 1e-32
BC000670-1|AAH00670.1| 325|Homo sapiens aldo-keto reductase fam... 138 1e-32
AL355480-3|CAI22459.1| 325|Homo sapiens aldo-keto reductase fam... 138 1e-32
AF112485-1|AAF01260.1| 325|Homo sapiens aldehyde reductase prot... 138 1e-32
AF036683-1|AAB92369.1| 325|Homo sapiens aldehyde reductase prot... 138 1e-32
U37100-1|AAC17469.1| 316|Homo sapiens aldose reductase-like pep... 138 2e-32
CR541801-1|CAG46600.1| 316|Homo sapiens AKR1B10 protein. 138 2e-32
BT006794-1|AAP35440.1| 316|Homo sapiens aldo-keto reductase fam... 138 2e-32
BC008837-1|AAH08837.1| 316|Homo sapiens aldo-keto reductase fam... 138 2e-32
BC005387-1|AAH05387.1| 316|Homo sapiens aldo-keto reductase fam... 138 2e-32
AF052577-1|AAC36465.1| 316|Homo sapiens aldo-keto reductase pro... 138 2e-32
AF524864-1|AAO13380.1| 316|Homo sapiens aldo-ketoreductase prot... 137 3e-32
D17793-1|BAA04619.2| 325|Homo sapiens KIAA0119 protein. 136 4e-32
DQ269985-1|ABB76132.1| 323|Homo sapiens type II 3a-hydroxystero... 136 4e-32
BT007286-1|AAP35950.1| 323|Homo sapiens aldo-keto reductase fam... 136 4e-32
BC019230-1|AAH19230.1| 323|Homo sapiens aldo-keto reductase fam... 136 4e-32
BC001479-1|AAH01479.1| 323|Homo sapiens aldo-keto reductase fam... 136 4e-32
AL391427-4|CAI14729.1| 323|Homo sapiens aldo-keto reductase fam... 136 4e-32
AB032157-1|BAA92892.1| 323|Homo sapiens prostaglandin F synthas... 136 4e-32
AB018580-1|BAA88488.1| 323|Homo sapiens hluPGFS protein. 136 4e-32
S68288-1|AAD14011.1| 323|Homo sapiens chlordecone reductase hom... 136 8e-32
L43839-1|AAB41916.1| 323|Homo sapiens 3-alpha-hydroxysteroid de... 136 8e-32
AF149416-1|AAF07272.2| 323|Homo sapiens 3-alpha hydroxysteroid ... 135 1e-31
AF263242-1|AAK58523.1| 320|Homo sapiens aldo-keto reductase loo... 123 6e-28
BC002862-1|AAH02862.1| 307|Homo sapiens AKR1CL2 protein protein. 118 1e-26
AB055603-1|BAC54568.1| 307|Homo sapiens aldo-keto reductase rel... 118 1e-26
AL713867-3|CAI16410.1| 247|Homo sapiens aldo-keto reductase fam... 109 6e-24
AB209796-1|BAD93033.1| 260|Homo sapiens aldo-keto reductase fam... 93 5e-19
AL391427-2|CAI14727.1| 302|Homo sapiens aldo-keto reductase fam... 83 8e-16
AL355303-1|CAI14201.1| 302|Homo sapiens aldo-keto reductase fam... 83 8e-16
AB209017-1|BAD92254.1| 286|Homo sapiens aldo-keto reductase fam... 77 4e-14
AF044961-1|AAC15671.1| 85|Homo sapiens aldose reductase-relate... 71 3e-12
AK058142-1|BAB71682.1| 146|Homo sapiens protein ( Homo sapiens ... 65 2e-10
AB040821-1|BAC54566.1| 263|Homo sapiens aldo-keto reductase rel... 52 6e-07
AB040820-1|BAC54565.1| 250|Homo sapiens aldo-keto reductase rel... 52 6e-07
AB040822-1|BAC54567.1| 222|Homo sapiens aldo-keto reductase rel... 49 1e-05
AB028065-1|BAA88489.1| 67|Homo sapiens prostaglandin F synthas... 46 8e-05
AK025747-1|BAB15231.1| 171|Homo sapiens protein ( Homo sapiens ... 33 1.1
AK001267-1|BAA91590.1| 639|Homo sapiens protein ( Homo sapiens ... 33 1.1
AC093727-1|AAX81992.1| 639|Homo sapiens unknown protein. 33 1.1
>CR542203-1|CAG47000.1| 316|Homo sapiens AKR1B1 protein.
Length = 316
Score = 145 bits (352), Expect = 1e-34
Identities = 77/204 (37%), Positives = 120/204 (58%), Gaps = 16/204 (7%)
Frame = -3
Query: 620 YLIHFPIXTKP-------DDS----PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQI 474
YLIH+PI KP D+S P + + L+TW M++ GL ++IG+SNFN Q+
Sbjct: 108 YLIHWPIGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQV 167
Query: 473 TRLVSNSYIR--PVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPP 300
+++ ++ P +NQIE +P TQE L+ +CQS GI V AYSP G P
Sbjct: 168 EMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPS 227
Query: 299 RSDDPTLTALANKYRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEVA 120
+DP + A+A K+ K+ Q+L+R+ + R L+ IPKS +RIA+N +FDF+L+ +++
Sbjct: 228 LLEDPRIKAIAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMT 287
Query: 119 AINQFNKNHRV---IDISDWKDYP 57
+ +N+N RV + + KDYP
Sbjct: 288 TLLSYNRNWRVCALLSCTSHKDYP 311
>X15414-1|CAA33460.1| 316|Homo sapiens protein ( Human mRNA for
aldose reductase (EC 1.1.1.2). ).
Length = 316
Score = 143 bits (347), Expect = 4e-34
Identities = 76/204 (37%), Positives = 119/204 (58%), Gaps = 16/204 (7%)
Frame = -3
Query: 620 YLIHFPIXTKP-------DDS----PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQI 474
YLIH+P KP D+S P + + L+TW M++ GL ++IG+SNFN Q+
Sbjct: 108 YLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQV 167
Query: 473 TRLVSNSYIR--PVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPP 300
+++ ++ P +NQIE +P TQE L+ +CQS GI V AYSP G P
Sbjct: 168 EMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPS 227
Query: 299 RSDDPTLTALANKYRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEVA 120
+DP + A+A K+ K+ Q+L+R+ + R L+ IPKS +RIA+N +FDF+L+ +++
Sbjct: 228 LLEDPRIKAIAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMT 287
Query: 119 AINQFNKNHRV---IDISDWKDYP 57
+ +N+N RV + + KDYP
Sbjct: 288 TLLSYNRNWRVCALLSCTSHKDYP 311
>M59783-1|AAA51712.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 143 bits (347), Expect = 4e-34
Identities = 76/204 (37%), Positives = 119/204 (58%), Gaps = 16/204 (7%)
Frame = -3
Query: 620 YLIHFPIXTKP-------DDS----PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQI 474
YLIH+P KP D+S P + + L+TW M++ GL ++IG+SNFN Q+
Sbjct: 108 YLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQV 167
Query: 473 TRLVSNSYIR--PVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPP 300
+++ ++ P +NQIE +P TQE L+ +CQS GI V AYSP G P
Sbjct: 168 EMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPS 227
Query: 299 RSDDPTLTALANKYRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEVA 120
+DP + A+A K+ K+ Q+L+R+ + R L+ IPKS +RIA+N +FDF+L+ +++
Sbjct: 228 LLEDPRIKAIAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMT 287
Query: 119 AINQFNKNHRV---IDISDWKDYP 57
+ +N+N RV + + KDYP
Sbjct: 288 TLLSYNRNWRVCALLSCTSHKDYP 311
>M34720-1|AAA35560.1| 316|Homo sapiens protein ( Human aldose
reductase mRNA, complete cds. ).
Length = 316
Score = 143 bits (347), Expect = 4e-34
Identities = 76/204 (37%), Positives = 119/204 (58%), Gaps = 16/204 (7%)
Frame = -3
Query: 620 YLIHFPIXTKP-------DDS----PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQI 474
YLIH+P KP D+S P + + L+TW M++ GL ++IG+SNFN Q+
Sbjct: 108 YLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQV 167
Query: 473 TRLVSNSYIR--PVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPP 300
+++ ++ P +NQIE +P TQE L+ +CQS GI V AYSP G P
Sbjct: 168 EMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPS 227
Query: 299 RSDDPTLTALANKYRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEVA 120
+DP + A+A K+ K+ Q+L+R+ + R L+ IPKS +RIA+N +FDF+L+ +++
Sbjct: 228 LLEDPRIKAIAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMT 287
Query: 119 AINQFNKNHRV---IDISDWKDYP 57
+ +N+N RV + + KDYP
Sbjct: 288 TLLSYNRNWRVCALLSCTSHKDYP 311
>J05474-1|AAA51715.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 143 bits (347), Expect = 4e-34
Identities = 76/204 (37%), Positives = 119/204 (58%), Gaps = 16/204 (7%)
Frame = -3
Query: 620 YLIHFPIXTKP-------DDS----PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQI 474
YLIH+P KP D+S P + + L+TW M++ GL ++IG+SNFN Q+
Sbjct: 108 YLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQV 167
Query: 473 TRLVSNSYIR--PVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPP 300
+++ ++ P +NQIE +P TQE L+ +CQS GI V AYSP G P
Sbjct: 168 EMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPS 227
Query: 299 RSDDPTLTALANKYRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEVA 120
+DP + A+A K+ K+ Q+L+R+ + R L+ IPKS +RIA+N +FDF+L+ +++
Sbjct: 228 LLEDPRIKAIAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMT 287
Query: 119 AINQFNKNHRV---IDISDWKDYP 57
+ +N+N RV + + KDYP
Sbjct: 288 TLLSYNRNWRVCALLSCTSHKDYP 311
>J05017-1|AAA51714.1| 316|Homo sapiens ALDR1 protein.
Length = 316
Score = 143 bits (347), Expect = 4e-34
Identities = 76/204 (37%), Positives = 119/204 (58%), Gaps = 16/204 (7%)
Frame = -3
Query: 620 YLIHFPIXTKP-------DDS----PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQI 474
YLIH+P KP D+S P + + L+TW M++ GL ++IG+SNFN Q+
Sbjct: 108 YLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQV 167
Query: 473 TRLVSNSYIR--PVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPP 300
+++ ++ P +NQIE +P TQE L+ +CQS GI V AYSP G P
Sbjct: 168 EMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPS 227
Query: 299 RSDDPTLTALANKYRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEVA 120
+DP + A+A K+ K+ Q+L+R+ + R L+ IPKS +RIA+N +FDF+L+ +++
Sbjct: 228 LLEDPRIKAIAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMT 287
Query: 119 AINQFNKNHRV---IDISDWKDYP 57
+ +N+N RV + + KDYP
Sbjct: 288 TLLSYNRNWRVCALLSCTSHKDYP 311
>J04795-1|AAA51713.1| 316|Homo sapiens ALDR1 protein.
Length = 316
Score = 143 bits (347), Expect = 4e-34
Identities = 76/204 (37%), Positives = 119/204 (58%), Gaps = 16/204 (7%)
Frame = -3
Query: 620 YLIHFPIXTKP-------DDS----PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQI 474
YLIH+P KP D+S P + + L+TW M++ GL ++IG+SNFN Q+
Sbjct: 108 YLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQV 167
Query: 473 TRLVSNSYIR--PVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPP 300
+++ ++ P +NQIE +P TQE L+ +CQS GI V AYSP G P
Sbjct: 168 EMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPS 227
Query: 299 RSDDPTLTALANKYRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEVA 120
+DP + A+A K+ K+ Q+L+R+ + R L+ IPKS +RIA+N +FDF+L+ +++
Sbjct: 228 LLEDPRIKAIAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMT 287
Query: 119 AINQFNKNHRV---IDISDWKDYP 57
+ +N+N RV + + KDYP
Sbjct: 288 TLLSYNRNWRVCALLSCTSHKDYP 311
>CR450351-1|CAG29347.1| 316|Homo sapiens AKR1B1 protein.
Length = 316
Score = 143 bits (347), Expect = 4e-34
Identities = 76/204 (37%), Positives = 119/204 (58%), Gaps = 16/204 (7%)
Frame = -3
Query: 620 YLIHFPIXTKP-------DDS----PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQI 474
YLIH+P +P D+S P + + L+TW M++ GL ++IG+SNFN Q+
Sbjct: 108 YLIHWPTGFRPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQV 167
Query: 473 TRLVSNSYIR--PVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPP 300
++S ++ P +NQIE +P TQE L+ +CQS GI V AYSP G P
Sbjct: 168 EMILSKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPS 227
Query: 299 RSDDPTLTALANKYRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEVA 120
+DP + A+A K+ K+ Q+L+R+ + R L+ IPKS +RIA+N +FDF+L+ +++
Sbjct: 228 LLEDPRIKAIAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMT 287
Query: 119 AINQFNKNHRV---IDISDWKDYP 57
+ +N+N RV + + KDYP
Sbjct: 288 TLLSYNRNWRVCALLSCTSHKDYP 311
>BT019859-1|AAV38662.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 143 bits (347), Expect = 4e-34
Identities = 76/204 (37%), Positives = 119/204 (58%), Gaps = 16/204 (7%)
Frame = -3
Query: 620 YLIHFPIXTKP-------DDS----PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQI 474
YLIH+P KP D+S P + + L+TW M++ GL ++IG+SNFN Q+
Sbjct: 108 YLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQV 167
Query: 473 TRLVSNSYIR--PVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPP 300
+++ ++ P +NQIE +P TQE L+ +CQS GI V AYSP G P
Sbjct: 168 EMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPS 227
Query: 299 RSDDPTLTALANKYRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEVA 120
+DP + A+A K+ K+ Q+L+R+ + R L+ IPKS +RIA+N +FDF+L+ +++
Sbjct: 228 LLEDPRIKAIAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMT 287
Query: 119 AINQFNKNHRV---IDISDWKDYP 57
+ +N+N RV + + KDYP
Sbjct: 288 TLLSYNRNWRVCALLSCTSHKDYP 311
>BC010391-1|AAH10391.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 143 bits (347), Expect = 4e-34
Identities = 76/204 (37%), Positives = 119/204 (58%), Gaps = 16/204 (7%)
Frame = -3
Query: 620 YLIHFPIXTKP-------DDS----PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQI 474
YLIH+P KP D+S P + + L+TW M++ GL ++IG+SNFN Q+
Sbjct: 108 YLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQV 167
Query: 473 TRLVSNSYIR--PVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPP 300
+++ ++ P +NQIE +P TQE L+ +CQS GI V AYSP G P
Sbjct: 168 EMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPS 227
Query: 299 RSDDPTLTALANKYRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEVA 120
+DP + A+A K+ K+ Q+L+R+ + R L+ IPKS +RIA+N +FDF+L+ +++
Sbjct: 228 LLEDPRIKAIAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMT 287
Query: 119 AINQFNKNHRV---IDISDWKDYP 57
+ +N+N RV + + KDYP
Sbjct: 288 TLLSYNRNWRVCALLSCTSHKDYP 311
>BC000260-1|AAH00260.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 143 bits (347), Expect = 4e-34
Identities = 76/204 (37%), Positives = 119/204 (58%), Gaps = 16/204 (7%)
Frame = -3
Query: 620 YLIHFPIXTKP-------DDS----PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQI 474
YLIH+P KP D+S P + + L+TW M++ GL ++IG+SNFN Q+
Sbjct: 108 YLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQV 167
Query: 473 TRLVSNSYIR--PVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPP 300
+++ ++ P +NQIE +P TQE L+ +CQS GI V AYSP G P
Sbjct: 168 EMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPS 227
Query: 299 RSDDPTLTALANKYRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEVA 120
+DP + A+A K+ K+ Q+L+R+ + R L+ IPKS +RIA+N +FDF+L+ +++
Sbjct: 228 LLEDPRIKAIAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMT 287
Query: 119 AINQFNKNHRV---IDISDWKDYP 57
+ +N+N RV + + KDYP
Sbjct: 288 TLLSYNRNWRVCALLSCTSHKDYP 311
>AF328729-1|AAN09721.1| 316|Homo sapiens CTCL tumor antigen
HD-CL-07 protein.
Length = 316
Score = 143 bits (347), Expect = 4e-34
Identities = 76/204 (37%), Positives = 119/204 (58%), Gaps = 16/204 (7%)
Frame = -3
Query: 620 YLIHFPIXTKP-------DDS----PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQI 474
YLIH+P KP D+S P + + L+TW M++ GL ++IG+SNFN Q+
Sbjct: 108 YLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQV 167
Query: 473 TRLVSNSYIR--PVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPP 300
+++ ++ P +NQIE +P TQE L+ +CQS GI V AYSP G P
Sbjct: 168 EMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPS 227
Query: 299 RSDDPTLTALANKYRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEVA 120
+DP + A+A K+ K+ Q+L+R+ + R L+ IPKS +RIA+N +FDF+L+ +++
Sbjct: 228 LLEDPRIKAIAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMT 287
Query: 119 AINQFNKNHRV---IDISDWKDYP 57
+ +N+N RV + + KDYP
Sbjct: 288 TLLSYNRNWRVCALLSCTSHKDYP 311
>AF032455-1|AAB88851.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 143 bits (347), Expect = 4e-34
Identities = 76/204 (37%), Positives = 119/204 (58%), Gaps = 16/204 (7%)
Frame = -3
Query: 620 YLIHFPIXTKP-------DDS----PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQI 474
YLIH+P KP D+S P + + L+TW M++ GL ++IG+SNFN Q+
Sbjct: 108 YLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQV 167
Query: 473 TRLVSNSYIR--PVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPP 300
+++ ++ P +NQIE +P TQE L+ +CQS GI V AYSP G P
Sbjct: 168 EMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPS 227
Query: 299 RSDDPTLTALANKYRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEVA 120
+DP + A+A K+ K+ Q+L+R+ + R L+ IPKS +RIA+N +FDF+L+ +++
Sbjct: 228 LLEDPRIKAIAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMT 287
Query: 119 AINQFNKNHRV---IDISDWKDYP 57
+ +N+N RV + + KDYP
Sbjct: 288 TLLSYNRNWRVCALLSCTSHKDYP 311
>U05861-1|AAA18115.1| 323|Homo sapiens hepatic dihydrodiol
dehydrogenase protein.
Length = 323
Score = 142 bits (345), Expect = 7e-34
Identities = 77/205 (37%), Positives = 116/205 (56%), Gaps = 14/205 (6%)
Frame = -3
Query: 620 YLIHFPIXTKPDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQI 474
YLIHFP+ KP + D +D TW+ ++ + GLA+SIGVSNFN Q+
Sbjct: 114 YLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQL 173
Query: 473 TRLVSNSYIR--PVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPP 300
+++ ++ PV NQ+E +P Q L+ C+S I ++AYS G P
Sbjct: 174 EMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSP 233
Query: 299 -RSDDPTLTALANKYRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEV 123
+DP L ALA K++++ I LRY + RG++ + KS N+QRI QN+ +F+FQLT EE+
Sbjct: 234 VLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEM 293
Query: 122 AAINQFNKNHRVIDISDWKDYPNYP 48
AI+ N+N R + + + PNYP
Sbjct: 294 KAIDGLNRNVRYLTLDIFAGPPNYP 318
>U05684-1|AAA16227.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 142 bits (345), Expect = 7e-34
Identities = 77/205 (37%), Positives = 116/205 (56%), Gaps = 14/205 (6%)
Frame = -3
Query: 620 YLIHFPIXTKPDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQI 474
YLIHFP+ KP + D +D TW+ ++ + GLA+SIGVSNFN Q+
Sbjct: 114 YLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQL 173
Query: 473 TRLVSNSYIR--PVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPP 300
+++ ++ PV NQ+E +P Q L+ C+S I ++AYS G P
Sbjct: 174 EMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSP 233
Query: 299 -RSDDPTLTALANKYRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEV 123
+DP L ALA K++++ I LRY + RG++ + KS N+QRI QN+ +F+FQLT EE+
Sbjct: 234 VLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEM 293
Query: 122 AAINQFNKNHRVIDISDWKDYPNYP 48
AI+ N+N R + + + PNYP
Sbjct: 294 KAIDGLNRNVRYLTLDIFAGPPNYP 318
>M86609-1|AAB02880.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 142 bits (345), Expect = 7e-34
Identities = 77/205 (37%), Positives = 116/205 (56%), Gaps = 14/205 (6%)
Frame = -3
Query: 620 YLIHFPIXTKPDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQI 474
YLIHFP+ KP + D +D TW+ ++ + GLA+SIGVSNFN Q+
Sbjct: 114 YLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQL 173
Query: 473 TRLVSNSYIR--PVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPP 300
+++ ++ PV NQ+E +P Q L+ C+S I ++AYS G P
Sbjct: 174 EMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSP 233
Query: 299 -RSDDPTLTALANKYRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEV 123
+DP L ALA K++++ I LRY + RG++ + KS N+QRI QN+ +F+FQLT EE+
Sbjct: 234 VLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEM 293
Query: 122 AAINQFNKNHRVIDISDWKDYPNYP 48
AI+ N+N R + + + PNYP
Sbjct: 294 KAIDGLNRNVRYLTLDIFAGPPNYP 318
>D26124-1|BAA05121.1| 306|Homo sapiens dihydrodiol dehydrogenase
isoform DD1 protein.
Length = 306
Score = 142 bits (345), Expect = 7e-34
Identities = 77/205 (37%), Positives = 116/205 (56%), Gaps = 14/205 (6%)
Frame = -3
Query: 620 YLIHFPIXTKPDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQI 474
YLIHFP+ KP + D +D TW+ ++ + GLA+SIGVSNFN Q+
Sbjct: 97 YLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQL 156
Query: 473 TRLVSNSYIR--PVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPP 300
+++ ++ PV NQ+E +P Q L+ C+S I ++AYS G P
Sbjct: 157 EMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSP 216
Query: 299 -RSDDPTLTALANKYRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEV 123
+DP L ALA K++++ I LRY + RG++ + KS N+QRI QN+ +F+FQLT EE+
Sbjct: 217 VLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEM 276
Query: 122 AAINQFNKNHRVIDISDWKDYPNYP 48
AI+ N+N R + + + PNYP
Sbjct: 277 KAIDGLNRNVRYLTLDIFAGPPNYP 301
>BT007197-1|AAP35861.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 142 bits (345), Expect = 7e-34
Identities = 77/205 (37%), Positives = 116/205 (56%), Gaps = 14/205 (6%)
Frame = -3
Query: 620 YLIHFPIXTKPDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQI 474
YLIHFP+ KP + D +D TW+ ++ + GLA+SIGVSNFN Q+
Sbjct: 114 YLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQL 173
Query: 473 TRLVSNSYIR--PVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPP 300
+++ ++ PV NQ+E +P Q L+ C+S I ++AYS G P
Sbjct: 174 EMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSP 233
Query: 299 -RSDDPTLTALANKYRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEV 123
+DP L ALA K++++ I LRY + RG++ + KS N+QRI QN+ +F+FQLT EE+
Sbjct: 234 VLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEM 293
Query: 122 AAINQFNKNHRVIDISDWKDYPNYP 48
AI+ N+N R + + + PNYP
Sbjct: 294 KAIDGLNRNVRYLTLDIFAGPPNYP 318
>BC040210-1|AAH40210.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 142 bits (345), Expect = 7e-34
Identities = 77/205 (37%), Positives = 116/205 (56%), Gaps = 14/205 (6%)
Frame = -3
Query: 620 YLIHFPIXTKPDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQI 474
YLIHFP+ KP + D +D TW+ ++ + GLA+SIGVSNFN Q+
Sbjct: 114 YLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQL 173
Query: 473 TRLVSNSYIR--PVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPP 300
+++ ++ PV NQ+E +P Q L+ C+S I ++AYS G P
Sbjct: 174 EMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSP 233
Query: 299 -RSDDPTLTALANKYRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEV 123
+DP L ALA K++++ I LRY + RG++ + KS N+QRI QN+ +F+FQLT EE+
Sbjct: 234 VLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEM 293
Query: 122 AAINQFNKNHRVIDISDWKDYPNYP 48
AI+ N+N R + + + PNYP
Sbjct: 294 KAIDGLNRNVRYLTLDIFAGPPNYP 318
>BC020216-1|AAH20216.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 142 bits (345), Expect = 7e-34
Identities = 77/205 (37%), Positives = 116/205 (56%), Gaps = 14/205 (6%)
Frame = -3
Query: 620 YLIHFPIXTKPDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQI 474
YLIHFP+ KP + D +D TW+ ++ + GLA+SIGVSNFN Q+
Sbjct: 114 YLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQL 173
Query: 473 TRLVSNSYIR--PVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPP 300
+++ ++ PV NQ+E +P Q L+ C+S I ++AYS G P
Sbjct: 174 EMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSP 233
Query: 299 -RSDDPTLTALANKYRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEV 123
+DP L ALA K++++ I LRY + RG++ + KS N+QRI QN+ +F+FQLT EE+
Sbjct: 234 VLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEM 293
Query: 122 AAINQFNKNHRVIDISDWKDYPNYP 48
AI+ N+N R + + + PNYP
Sbjct: 294 KAIDGLNRNVRYLTLDIFAGPPNYP 318
>BC015490-1|AAH15490.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 142 bits (345), Expect = 7e-34
Identities = 77/205 (37%), Positives = 116/205 (56%), Gaps = 14/205 (6%)
Frame = -3
Query: 620 YLIHFPIXTKPDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQI 474
YLIHFP+ KP + D +D TW+ ++ + GLA+SIGVSNFN Q+
Sbjct: 114 YLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQL 173
Query: 473 TRLVSNSYIR--PVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPP 300
+++ ++ PV NQ+E +P Q L+ C+S I ++AYS G P
Sbjct: 174 EMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSP 233
Query: 299 -RSDDPTLTALANKYRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEV 123
+DP L ALA K++++ I LRY + RG++ + KS N+QRI QN+ +F+FQLT EE+
Sbjct: 234 VLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEM 293
Query: 122 AAINQFNKNHRVIDISDWKDYPNYP 48
AI+ N+N R + + + PNYP
Sbjct: 294 KAIDGLNRNVRYLTLDIFAGPPNYP 318
>AL713867-2|CAI16409.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 142 bits (345), Expect = 7e-34
Identities = 77/205 (37%), Positives = 116/205 (56%), Gaps = 14/205 (6%)
Frame = -3
Query: 620 YLIHFPIXTKPDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQI 474
YLIHFP+ KP + D +D TW+ ++ + GLA+SIGVSNFN Q+
Sbjct: 114 YLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQL 173
Query: 473 TRLVSNSYIR--PVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPP 300
+++ ++ PV NQ+E +P Q L+ C+S I ++AYS G P
Sbjct: 174 EMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSP 233
Query: 299 -RSDDPTLTALANKYRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEV 123
+DP L ALA K++++ I LRY + RG++ + KS N+QRI QN+ +F+FQLT EE+
Sbjct: 234 VLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEM 293
Query: 122 AAINQFNKNHRVIDISDWKDYPNYP 48
AI+ N+N R + + + PNYP
Sbjct: 294 KAIDGLNRNVRYLTLDIFAGPPNYP 318
>AB032150-1|BAA92886.1| 323|Homo sapiens 20 alph-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 142 bits (345), Expect = 7e-34
Identities = 77/205 (37%), Positives = 116/205 (56%), Gaps = 14/205 (6%)
Frame = -3
Query: 620 YLIHFPIXTKPDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQI 474
YLIHFP+ KP + D +D TW+ ++ + GLA+SIGVSNFN Q+
Sbjct: 114 YLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQL 173
Query: 473 TRLVSNSYIR--PVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPP 300
+++ ++ PV NQ+E +P Q L+ C+S I ++AYS G P
Sbjct: 174 EMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSP 233
Query: 299 -RSDDPTLTALANKYRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEV 123
+DP L ALA K++++ I LRY + RG++ + KS N+QRI QN+ +F+FQLT EE+
Sbjct: 234 VLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEM 293
Query: 122 AAINQFNKNHRVIDISDWKDYPNYP 48
AI+ N+N R + + + PNYP
Sbjct: 294 KAIDGLNRNVRYLTLDIFAGPPNYP 318
>AB031083-1|BAA92883.1| 323|Homo sapiens 20 alpha-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 142 bits (345), Expect = 7e-34
Identities = 77/205 (37%), Positives = 116/205 (56%), Gaps = 14/205 (6%)
Frame = -3
Query: 620 YLIHFPIXTKPDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQI 474
YLIHFP+ KP + D +D TW+ ++ + GLA+SIGVSNFN Q+
Sbjct: 114 YLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQL 173
Query: 473 TRLVSNSYIR--PVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPP 300
+++ ++ PV NQ+E +P Q L+ C+S I ++AYS G P
Sbjct: 174 EMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSP 233
Query: 299 -RSDDPTLTALANKYRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEV 123
+DP L ALA K++++ I LRY + RG++ + KS N+QRI QN+ +F+FQLT EE+
Sbjct: 234 VLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEM 293
Query: 122 AAINQFNKNHRVIDISDWKDYPNYP 48
AI+ N+N R + + + PNYP
Sbjct: 294 KAIDGLNRNVRYLTLDIFAGPPNYP 318
>Z28339-1|CAA82193.1| 326|Homo sapiens delta 4-3-oxosteroid 5
beta-reductase protein.
Length = 326
Score = 142 bits (343), Expect = 1e-33
Identities = 79/207 (38%), Positives = 115/207 (55%), Gaps = 16/207 (7%)
Frame = -3
Query: 620 YLIHFPIXTKPDDS----PDNIDYL-------ETWQGMQDARQLGLARSIGVSNFNATQI 474
Y+I P+ KP D +N +L TW+ M+ + GL +S+GVSNFN Q+
Sbjct: 117 YIIEVPMAFKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQL 176
Query: 473 TRLVSNSYIR--PVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTG---A 309
+++ ++ PV NQ+E +P TQ L+ CQ I + AYSP G SR +
Sbjct: 177 ELILNKPGLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLG--TSRNPIWVNVS 234
Query: 308 PPPRSDDPTLTALANKYRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFE 129
PP D L +L +Y K+ QI+LR+ I RG++ IPKS N +RI +N +FDF LT E
Sbjct: 235 SPPLLKDALLNSLGKRYNKTAAQIVLRFNIQRGVVVIPKSFNLERIKENFQIFDFSLTEE 294
Query: 128 EVAAINQFNKNHRVIDISDWKDYPNYP 48
E+ I NKN R +++ W+D+P YP
Sbjct: 295 EMKDIEALNKNVRFVELLMWRDHPEYP 321
>BC130627-1|AAI30628.1| 326|Homo sapiens aldo-keto reductase family
1, member D1 (delta 4-3-ketosteroid-5-beta-reductase
protein.
Length = 326
Score = 142 bits (343), Expect = 1e-33
Identities = 79/207 (38%), Positives = 115/207 (55%), Gaps = 16/207 (7%)
Frame = -3
Query: 620 YLIHFPIXTKPDDS----PDNIDYL-------ETWQGMQDARQLGLARSIGVSNFNATQI 474
Y+I P+ KP D +N +L TW+ M+ + GL +S+GVSNFN Q+
Sbjct: 117 YIIEVPMAFKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQL 176
Query: 473 TRLVSNSYIR--PVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTG---A 309
+++ ++ PV NQ+E +P TQ L+ CQ I + AYSP G SR +
Sbjct: 177 ELILNKPGLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLG--TSRNPIWVNVS 234
Query: 308 PPPRSDDPTLTALANKYRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFE 129
PP D L +L +Y K+ QI+LR+ I RG++ IPKS N +RI +N +FDF LT E
Sbjct: 235 SPPLLKDALLNSLGKRYNKTAAQIVLRFNIQRGVVVIPKSFNLERIKENFQIFDFSLTEE 294
Query: 128 EVAAINQFNKNHRVIDISDWKDYPNYP 48
E+ I NKN R +++ W+D+P YP
Sbjct: 295 EMKDIEALNKNVRFVELLMWRDHPEYP 321
>BC130625-1|AAI30626.1| 326|Homo sapiens aldo-keto reductase family
1, member D1 (delta 4-3-ketosteroid-5-beta-reductase
protein.
Length = 326
Score = 142 bits (343), Expect = 1e-33
Identities = 79/207 (38%), Positives = 115/207 (55%), Gaps = 16/207 (7%)
Frame = -3
Query: 620 YLIHFPIXTKPDDS----PDNIDYL-------ETWQGMQDARQLGLARSIGVSNFNATQI 474
Y+I P+ KP D +N +L TW+ M+ + GL +S+GVSNFN Q+
Sbjct: 117 YIIEVPMAFKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQL 176
Query: 473 TRLVSNSYIR--PVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTG---A 309
+++ ++ PV NQ+E +P TQ L+ CQ I + AYSP G SR +
Sbjct: 177 ELILNKPGLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLG--TSRNPIWVNVS 234
Query: 308 PPPRSDDPTLTALANKYRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFE 129
PP D L +L +Y K+ QI+LR+ I RG++ IPKS N +RI +N +FDF LT E
Sbjct: 235 SPPLLKDALLNSLGKRYNKTAAQIVLRFNIQRGVVVIPKSFNLERIKENFQIFDFSLTEE 294
Query: 128 EVAAINQFNKNHRVIDISDWKDYPNYP 48
E+ I NKN R +++ W+D+P YP
Sbjct: 295 EMKDIEALNKNVRFVELLMWRDHPEYP 321
>AF283659-1|AAG39381.1| 326|Homo sapiens 5-beta steroid reductase
protein.
Length = 326
Score = 142 bits (343), Expect = 1e-33
Identities = 79/207 (38%), Positives = 115/207 (55%), Gaps = 16/207 (7%)
Frame = -3
Query: 620 YLIHFPIXTKPDDS----PDNIDYL-------ETWQGMQDARQLGLARSIGVSNFNATQI 474
Y+I P+ KP D +N +L TW+ M+ + GL +S+GVSNFN Q+
Sbjct: 117 YIIEVPMAFKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQL 176
Query: 473 TRLVSNSYIR--PVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTG---A 309
+++ ++ PV NQ+E +P TQ L+ CQ I + AYSP G SR +
Sbjct: 177 ELILNKPGLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLG--TSRNPIWVNVS 234
Query: 308 PPPRSDDPTLTALANKYRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFE 129
PP D L +L +Y K+ QI+LR+ I RG++ IPKS N +RI +N +FDF LT E
Sbjct: 235 SPPLLKDALLNSLGKRYNKTAAQIVLRFNIQRGVVVIPKSFNLERIKENFQIFDFSLTEE 294
Query: 128 EVAAINQFNKNHRVIDISDWKDYPNYP 48
E+ I NKN R +++ W+D+P YP
Sbjct: 295 EMKDIEALNKNVRFVELLMWRDHPEYP 321
>S68287-1|AAD14010.1| 323|Homo sapiens chlordecone reductase
protein.
Length = 323
Score = 141 bits (342), Expect = 2e-33
Identities = 74/205 (36%), Positives = 120/205 (58%), Gaps = 14/205 (6%)
Frame = -3
Query: 620 YLIHFPIXTKPDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQI 474
YL+HFP+ KP ++P D +D TW+ M+ + GLA+SIGVSNFN Q+
Sbjct: 114 YLLHFPMALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQL 173
Query: 473 TRLVSNSYIR--PVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPP 300
+++ ++ PV NQ+E +P Q L+ C+S I ++A+S G + P
Sbjct: 174 EMILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSP 233
Query: 299 -RSDDPTLTALANKYRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEV 123
+DP L ALA K++++ I LRY + RG++ + KS N+QRI +NI +F+FQLT E++
Sbjct: 234 VLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRENIQVFEFQLTSEDM 293
Query: 122 AAINQFNKNHRVIDISDWKDYPNYP 48
++ N+N+R + + D+P+YP
Sbjct: 294 KVLDGLNRNYRYVVMDFLMDHPDYP 318
>M33375-1|AAA35658.1| 308|Homo sapiens protein ( Human chlordecone
reductase mRNA, complete cds. ).
Length = 308
Score = 141 bits (342), Expect = 2e-33
Identities = 74/205 (36%), Positives = 120/205 (58%), Gaps = 14/205 (6%)
Frame = -3
Query: 620 YLIHFPIXTKPDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQI 474
YL+HFP+ KP ++P D +D TW+ M+ + GLA+SIGVSNFN Q+
Sbjct: 99 YLLHFPMALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQL 158
Query: 473 TRLVSNSYIR--PVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPP 300
+++ ++ PV NQ+E +P Q L+ C+S I ++A+S G + P
Sbjct: 159 EMILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSP 218
Query: 299 -RSDDPTLTALANKYRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEV 123
+DP L ALA K++++ I LRY + RG++ + KS N+QRI +NI +F+FQLT E++
Sbjct: 219 VLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRENIQVFEFQLTSEDM 278
Query: 122 AAINQFNKNHRVIDISDWKDYPNYP 48
++ N+N+R + + D+P+YP
Sbjct: 279 KVLDGLNRNYRYVVMDFLMDHPDYP 303
>D26125-1|BAA05122.1| 321|Homo sapiens 3
alpha-hydroxysteroid/dihydrodiol dehydrogenase DD4
protein.
Length = 321
Score = 141 bits (342), Expect = 2e-33
Identities = 74/205 (36%), Positives = 120/205 (58%), Gaps = 14/205 (6%)
Frame = -3
Query: 620 YLIHFPIXTKPDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQI 474
YL+HFP+ KP ++P D +D TW+ M+ + GLA+SIGVSNFN Q+
Sbjct: 112 YLLHFPMALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQL 171
Query: 473 TRLVSNSYIR--PVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPP 300
+++ ++ PV NQ+E +P Q L+ C+S I ++A+S G + P
Sbjct: 172 EMILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSP 231
Query: 299 -RSDDPTLTALANKYRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEV 123
+DP L ALA K++++ I LRY + RG++ + KS N+QRI +NI +F+FQLT E++
Sbjct: 232 VLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRENIQVFEFQLTSEDM 291
Query: 122 AAINQFNKNHRVIDISDWKDYPNYP 48
++ N+N+R + + D+P+YP
Sbjct: 292 KVLDGLNRNYRYVVMDFLMDHPDYP 316
>AB045829-1|BAA99542.1| 323|Homo sapiens 3alpha-hydroxysteroid
dehydrogenase variant protein.
Length = 323
Score = 141 bits (342), Expect = 2e-33
Identities = 74/205 (36%), Positives = 120/205 (58%), Gaps = 14/205 (6%)
Frame = -3
Query: 620 YLIHFPIXTKPDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQI 474
YL+HFP+ KP ++P D +D TW+ M+ + GLA+SIGVSNFN Q+
Sbjct: 114 YLLHFPMALKPGETPLPKDENGKVIFDTVDLCATWEVMEKCKDAGLAKSIGVSNFNCRQL 173
Query: 473 TRLVSNSYIR--PVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPP 300
+++ ++ PV NQ+E +P Q L+ C+S I ++A+S G + P
Sbjct: 174 EMILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSP 233
Query: 299 -RSDDPTLTALANKYRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEV 123
+DP L ALA K++++ I LRY + RG++ + KS N+QRI +NI +F+FQLT E++
Sbjct: 234 VLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRENIQVFEFQLTSEDM 293
Query: 122 AAINQFNKNHRVIDISDWKDYPNYP 48
++ N+N+R + + D+P+YP
Sbjct: 294 KVLDGLNRNYRYVVMDFVMDHPDYP 318
>AB032163-1|BAA92893.1| 323|Homo sapiens dihydrodiol dehydrogenase
4 protein.
Length = 323
Score = 141 bits (342), Expect = 2e-33
Identities = 74/205 (36%), Positives = 120/205 (58%), Gaps = 14/205 (6%)
Frame = -3
Query: 620 YLIHFPIXTKPDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQI 474
YL+HFP+ KP ++P D +D TW+ M+ + GLA+SIGVSNFN Q+
Sbjct: 114 YLLHFPMALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQL 173
Query: 473 TRLVSNSYIR--PVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPP 300
+++ ++ PV NQ+E +P Q L+ C+S I ++A+S G + P
Sbjct: 174 EMILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSP 233
Query: 299 -RSDDPTLTALANKYRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEV 123
+DP L ALA K++++ I LRY + RG++ + KS N+QRI +NI +F+FQLT E++
Sbjct: 234 VLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRENIQVFEFQLTSEDM 293
Query: 122 AAINQFNKNHRVIDISDWKDYPNYP 48
++ N+N+R + + D+P+YP
Sbjct: 294 KVLDGLNRNYRYVVMDFLMDHPDYP 318
>AB031085-1|BAA92885.1| 323|Homo sapiens dihydrodiol dehydrogenase
4 protein.
Length = 323
Score = 141 bits (342), Expect = 2e-33
Identities = 74/205 (36%), Positives = 120/205 (58%), Gaps = 14/205 (6%)
Frame = -3
Query: 620 YLIHFPIXTKPDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQI 474
YL+HFP+ KP ++P D +D TW+ M+ + GLA+SIGVSNFN Q+
Sbjct: 114 YLLHFPMALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQL 173
Query: 473 TRLVSNSYIR--PVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPP 300
+++ ++ PV NQ+E +P Q L+ C+S I ++A+S G + P
Sbjct: 174 EMILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSP 233
Query: 299 -RSDDPTLTALANKYRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEV 123
+DP L ALA K++++ I LRY + RG++ + KS N+QRI +NI +F+FQLT E++
Sbjct: 234 VLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRENIQVFEFQLTSEDM 293
Query: 122 AAINQFNKNHRVIDISDWKDYPNYP 48
++ N+N+R + + D+P+YP
Sbjct: 294 KVLDGLNRNYRYVVMDFLMDHPDYP 318
>U05598-1|AAA20937.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 141 bits (341), Expect = 2e-33
Identities = 77/205 (37%), Positives = 115/205 (56%), Gaps = 14/205 (6%)
Frame = -3
Query: 620 YLIHFPIXTKPDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQI 474
YLIHFP+ KP + D +D TW+ M+ + GLA+SIGVSNFN +
Sbjct: 114 YLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLL 173
Query: 473 TRLVSNSYIR--PVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPP 300
+++ ++ PV NQ+E +P Q L+ C+S I ++AYS G P
Sbjct: 174 EMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSP 233
Query: 299 -RSDDPTLTALANKYRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEV 123
+DP L ALA K++++ I LRY + RG++ + KS N+QRI QN+ +F+FQLT EE+
Sbjct: 234 VLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEM 293
Query: 122 AAINQFNKNHRVIDISDWKDYPNYP 48
AI+ N+N R + + + PNYP
Sbjct: 294 KAIDGLNRNVRYLTLDIFAGPPNYP 318
>S68330-1|AAD14013.1| 323|Homo sapiens chlordecone reductase
homolog protein.
Length = 323
Score = 141 bits (341), Expect = 2e-33
Identities = 77/205 (37%), Positives = 115/205 (56%), Gaps = 14/205 (6%)
Frame = -3
Query: 620 YLIHFPIXTKPDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQI 474
YLIHFP+ KP + D +D TW+ M+ + GLA+SIGVSNFN +
Sbjct: 114 YLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLL 173
Query: 473 TRLVSNSYIR--PVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPP 300
+++ ++ PV NQ+E +P Q L+ C+S I ++AYS G P
Sbjct: 174 EMILNEPGLKYEPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSP 233
Query: 299 -RSDDPTLTALANKYRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEV 123
+DP L ALA K++++ I LRY + RG++ + KS N+QRI QN+ +F+FQLT EE+
Sbjct: 234 VLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEM 293
Query: 122 AAINQFNKNHRVIDISDWKDYPNYP 48
AI+ N+N R + + + PNYP
Sbjct: 294 KAIDGLNRNVRYLTLDIFAGPPNYP 318
>L32592-1|AAB38486.1| 323|Homo sapiens dihydrodiol
dehydrogenase/bile acid-binding protein protein.
Length = 323
Score = 141 bits (341), Expect = 2e-33
Identities = 77/205 (37%), Positives = 115/205 (56%), Gaps = 14/205 (6%)
Frame = -3
Query: 620 YLIHFPIXTKPDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQI 474
YLIHFP+ KP + D +D TW+ M+ + GLA+SIGVSNFN +
Sbjct: 114 YLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLL 173
Query: 473 TRLVSNSYIR--PVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPP 300
+++ ++ PV NQ+E +P Q L+ C+S I ++AYS G P
Sbjct: 174 EMILNEPGLKYEPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSP 233
Query: 299 -RSDDPTLTALANKYRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEV 123
+DP L ALA K++++ I LRY + RG++ + KS N+QRI QN+ +F+FQLT EE+
Sbjct: 234 VLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEM 293
Query: 122 AAINQFNKNHRVIDISDWKDYPNYP 48
AI+ N+N R + + + PNYP
Sbjct: 294 KAIDGLNRNVRYLTLDIFAGPPNYP 318
>BT006653-1|AAP35299.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 141 bits (341), Expect = 2e-33
Identities = 77/205 (37%), Positives = 115/205 (56%), Gaps = 14/205 (6%)
Frame = -3
Query: 620 YLIHFPIXTKPDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQI 474
YLIHFP+ KP + D +D TW+ M+ + GLA+SIGVSNFN +
Sbjct: 114 YLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLL 173
Query: 473 TRLVSNSYIR--PVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPP 300
+++ ++ PV NQ+E +P Q L+ C+S I ++AYS G P
Sbjct: 174 EMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSP 233
Query: 299 -RSDDPTLTALANKYRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEV 123
+DP L ALA K++++ I LRY + RG++ + KS N+QRI QN+ +F+FQLT EE+
Sbjct: 234 VLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEM 293
Query: 122 AAINQFNKNHRVIDISDWKDYPNYP 48
AI+ N+N R + + + PNYP
Sbjct: 294 KAIDGLNRNVRYLTLDIFAGPPNYP 318
>BC063574-1|AAH63574.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 141 bits (341), Expect = 2e-33
Identities = 77/205 (37%), Positives = 115/205 (56%), Gaps = 14/205 (6%)
Frame = -3
Query: 620 YLIHFPIXTKPDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQI 474
YLIHFP+ KP + D +D TW+ M+ + GLA+SIGVSNFN +
Sbjct: 114 YLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLL 173
Query: 473 TRLVSNSYIR--PVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPP 300
+++ ++ PV NQ+E +P Q L+ C+S I ++AYS G P
Sbjct: 174 EMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSP 233
Query: 299 -RSDDPTLTALANKYRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEV 123
+DP L ALA K++++ I LRY + RG++ + KS N+QRI QN+ +F+FQLT EE+
Sbjct: 234 VLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEM 293
Query: 122 AAINQFNKNHRVIDISDWKDYPNYP 48
AI+ N+N R + + + PNYP
Sbjct: 294 KAIDGLNRNVRYLTLDIFAGPPNYP 318
>BC007024-1|AAH07024.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 141 bits (341), Expect = 2e-33
Identities = 77/205 (37%), Positives = 115/205 (56%), Gaps = 14/205 (6%)
Frame = -3
Query: 620 YLIHFPIXTKPDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQI 474
YLIHFP+ KP + D +D TW+ M+ + GLA+SIGVSNFN +
Sbjct: 114 YLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLL 173
Query: 473 TRLVSNSYIR--PVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPP 300
+++ ++ PV NQ+E +P Q L+ C+S I ++AYS G P
Sbjct: 174 EMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSP 233
Query: 299 -RSDDPTLTALANKYRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEV 123
+DP L ALA K++++ I LRY + RG++ + KS N+QRI QN+ +F+FQLT EE+
Sbjct: 234 VLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEM 293
Query: 122 AAINQFNKNHRVIDISDWKDYPNYP 48
AI+ N+N R + + + PNYP
Sbjct: 294 KAIDGLNRNVRYLTLDIFAGPPNYP 318
>AL713867-1|CAI16408.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 141 bits (341), Expect = 2e-33
Identities = 77/205 (37%), Positives = 115/205 (56%), Gaps = 14/205 (6%)
Frame = -3
Query: 620 YLIHFPIXTKPDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQI 474
YLIHFP+ KP + D +D TW+ M+ + GLA+SIGVSNFN +
Sbjct: 114 YLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLL 173
Query: 473 TRLVSNSYIR--PVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPP 300
+++ ++ PV NQ+E +P Q L+ C+S I ++AYS G P
Sbjct: 174 EMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSP 233
Query: 299 -RSDDPTLTALANKYRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEV 123
+DP L ALA K++++ I LRY + RG++ + KS N+QRI QN+ +F+FQLT EE+
Sbjct: 234 VLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEM 293
Query: 122 AAINQFNKNHRVIDISDWKDYPNYP 48
AI+ N+N R + + + PNYP
Sbjct: 294 KAIDGLNRNVRYLTLDIFAGPPNYP 318
>AL391427-1|CAI14726.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 141 bits (341), Expect = 2e-33
Identities = 77/205 (37%), Positives = 115/205 (56%), Gaps = 14/205 (6%)
Frame = -3
Query: 620 YLIHFPIXTKPDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQI 474
YLIHFP+ KP + D +D TW+ M+ + GLA+SIGVSNFN +
Sbjct: 114 YLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLL 173
Query: 473 TRLVSNSYIR--PVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPP 300
+++ ++ PV NQ+E +P Q L+ C+S I ++AYS G P
Sbjct: 174 EMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSP 233
Query: 299 -RSDDPTLTALANKYRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEV 123
+DP L ALA K++++ I LRY + RG++ + KS N+QRI QN+ +F+FQLT EE+
Sbjct: 234 VLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEM 293
Query: 122 AAINQFNKNHRVIDISDWKDYPNYP 48
AI+ N+N R + + + PNYP
Sbjct: 294 KAIDGLNRNVRYLTLDIFAGPPNYP 318
>AL355303-2|CAI14202.1| 323|Homo sapiens aldo-keto reductase family
1, member C4 (chlordecone reductase; 3-alpha hydroxy
protein.
Length = 323
Score = 141 bits (341), Expect = 2e-33
Identities = 74/205 (36%), Positives = 120/205 (58%), Gaps = 14/205 (6%)
Frame = -3
Query: 620 YLIHFPIXTKPDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQI 474
YL+HFP+ KP ++P D +D TW+ M+ + GLA+SIGVSNFN Q+
Sbjct: 114 YLLHFPMALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQL 173
Query: 473 TRLVSNSYIR--PVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPP 300
+++ ++ PV NQ+E +P Q L+ C+S I ++A+S G + P
Sbjct: 174 EMILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSP 233
Query: 299 -RSDDPTLTALANKYRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEV 123
+DP L ALA K++++ I LRY + RG++ + KS N+QRI +NI +F+FQLT E++
Sbjct: 234 VLLEDPVLCALAKKHKQTPALIALRYQLQRGVVVLAKSYNEQRIRENIQVFEFQLTSEDM 293
Query: 122 AAINQFNKNHRVIDISDWKDYPNYP 48
++ N+N+R + + D+P+YP
Sbjct: 294 KVLDGLNRNYRYVVMDFLMDHPDYP 318
>AB032153-1|BAA92891.1| 323|Homo sapiens bile acid-binding protein
protein.
Length = 323
Score = 141 bits (341), Expect = 2e-33
Identities = 77/205 (37%), Positives = 115/205 (56%), Gaps = 14/205 (6%)
Frame = -3
Query: 620 YLIHFPIXTKPDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQI 474
YLIHFP+ KP + D +D TW+ M+ + GLA+SIGVSNFN +
Sbjct: 114 YLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLL 173
Query: 473 TRLVSNSYIR--PVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPP 300
+++ ++ PV NQ+E +P Q L+ C+S I ++AYS G P
Sbjct: 174 EMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSP 233
Query: 299 -RSDDPTLTALANKYRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEV 123
+DP L ALA K++++ I LRY + RG++ + KS N+QRI QN+ +F+FQLT EE+
Sbjct: 234 VLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEM 293
Query: 122 AAINQFNKNHRVIDISDWKDYPNYP 48
AI+ N+N R + + + PNYP
Sbjct: 294 KAIDGLNRNVRYLTLDIFAGPPNYP 318
>AB031084-1|BAA92884.1| 323|Homo sapiens bile acid-binding protein
protein.
Length = 323
Score = 141 bits (341), Expect = 2e-33
Identities = 77/205 (37%), Positives = 115/205 (56%), Gaps = 14/205 (6%)
Frame = -3
Query: 620 YLIHFPIXTKPDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQI 474
YLIHFP+ KP + D +D TW+ M+ + GLA+SIGVSNFN +
Sbjct: 114 YLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLL 173
Query: 473 TRLVSNSYIR--PVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPP 300
+++ ++ PV NQ+E +P Q L+ C+S I ++AYS G P
Sbjct: 174 EMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSP 233
Query: 299 -RSDDPTLTALANKYRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEV 123
+DP L ALA K++++ I LRY + RG++ + KS N+QRI QN+ +F+FQLT EE+
Sbjct: 234 VLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEM 293
Query: 122 AAINQFNKNHRVIDISDWKDYPNYP 48
AI+ N+N R + + + PNYP
Sbjct: 294 KAIDGLNRNVRYLTLDIFAGPPNYP 318
>AB021654-1|BAA36169.1| 323|Homo sapiens DD2/bile acid-binding
protein/AKR1C2/3alpha-hydroxysteroid dehydrogenase type
3 protein.
Length = 323
Score = 141 bits (341), Expect = 2e-33
Identities = 77/205 (37%), Positives = 115/205 (56%), Gaps = 14/205 (6%)
Frame = -3
Query: 620 YLIHFPIXTKPDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQI 474
YLIHFP+ KP + D +D TW+ M+ + GLA+SIGVSNFN +
Sbjct: 114 YLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLL 173
Query: 473 TRLVSNSYIR--PVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPP 300
+++ ++ PV NQ+E +P Q L+ C+S I ++AYS G P
Sbjct: 174 EMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSP 233
Query: 299 -RSDDPTLTALANKYRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEV 123
+DP L ALA K++++ I LRY + RG++ + KS N+QRI QN+ +F+FQLT EE+
Sbjct: 234 VLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEM 293
Query: 122 AAINQFNKNHRVIDISDWKDYPNYP 48
AI+ N+N R + + + PNYP
Sbjct: 294 KAIDGLNRNVRYLTLDIFAGPPNYP 318
>S68290-1|AAD14012.1| 320|Homo sapiens chlordecone reductase
homolog protein.
Length = 320
Score = 140 bits (340), Expect = 3e-33
Identities = 75/205 (36%), Positives = 116/205 (56%), Gaps = 14/205 (6%)
Frame = -3
Query: 620 YLIHFPIXTKPDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQI 474
YLIHFP+ KP + D +D TW+ ++ + LA+SIGVSNFN + +
Sbjct: 111 YLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAELAKSIGVSNFNRSTL 170
Query: 473 TRLVSNS--YIRPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPP 300
+++ ++PV NQ+E +P Q L+ C+S I ++AYS G + P
Sbjct: 171 EMILNKPGLQVKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSLREEPWVDPNSP 230
Query: 299 -RSDDPTLTALANKYRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEV 123
+DP L ALA K++++ I LRY + RG++ + KS N+QRI QN+ +F+FQLT EE+
Sbjct: 231 VLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEM 290
Query: 122 AAINQFNKNHRVIDISDWKDYPNYP 48
AI+ N+N R + + + PNYP
Sbjct: 291 KAIDGLNRNVRYLTLDIFAGPPNYP 315
>BC020744-1|AAH20744.1| 323|Homo sapiens aldo-keto reductase family
1, member C4 (chlordecone reductase; 3-alpha hydroxy
protein.
Length = 323
Score = 140 bits (340), Expect = 3e-33
Identities = 74/205 (36%), Positives = 120/205 (58%), Gaps = 14/205 (6%)
Frame = -3
Query: 620 YLIHFPIXTKPDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQI 474
YL+HFP+ KP ++P D +D TW+ M+ + GLA+SIGVSNFN Q+
Sbjct: 114 YLLHFPMALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNYRQL 173
Query: 473 TRLVSNSYIR--PVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPP 300
+++ ++ PV NQ+E +P Q L+ C+S I ++A+S G + P
Sbjct: 174 EMILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSP 233
Query: 299 -RSDDPTLTALANKYRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEV 123
+DP L ALA K++++ I LRY + RG++ + KS N+QRI +NI +F+FQLT E++
Sbjct: 234 VLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRENIQVFEFQLTSEDM 293
Query: 122 AAINQFNKNHRVIDISDWKDYPNYP 48
++ N+N+R + + D+P+YP
Sbjct: 294 KVLDGLNRNYRYVVMDFLMDHPDYP 318
>J04794-1|AAA51711.1| 325|Homo sapiens ALDR1 protein.
Length = 325
Score = 138 bits (335), Expect = 1e-32
Identities = 74/190 (38%), Positives = 109/190 (57%), Gaps = 11/190 (5%)
Frame = -3
Query: 620 YLIHFPIXTKPDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQI 474
YL+H+P + D+P D+ Y ETW+ ++ GL +++G+SNFN+ QI
Sbjct: 110 YLMHWPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQI 169
Query: 473 TRLVSNSYIRPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPPRS 294
++S + +RP + Q+E +P Q L+AHCQ+ G+ V AYSP G + P
Sbjct: 170 DDILSVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLL 229
Query: 293 DDPTLTALANKYRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAI 114
++P + ALA KY +S QILLR+ + R +I IPKS RI QNI +FDF + EE+ +
Sbjct: 230 EEPVVLALAEKYGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQL 289
Query: 113 NQFNKNHRVI 84
N NKN R I
Sbjct: 290 NALNKNWRYI 299
>CR457010-1|CAG33291.1| 325|Homo sapiens AKR1A1 protein.
Length = 325
Score = 138 bits (335), Expect = 1e-32
Identities = 74/190 (38%), Positives = 109/190 (57%), Gaps = 11/190 (5%)
Frame = -3
Query: 620 YLIHFPIXTKPDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQI 474
YL+H+P + D+P D+ Y ETW+ ++ GL +++G+SNFN+ QI
Sbjct: 110 YLMHWPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQI 169
Query: 473 TRLVSNSYIRPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPPRS 294
++S + +RP + Q+E +P Q L+AHCQ+ G+ V AYSP G + P
Sbjct: 170 DDILSVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLL 229
Query: 293 DDPTLTALANKYRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAI 114
++P + ALA KY +S QILLR+ + R +I IPKS RI QNI +FDF + EE+ +
Sbjct: 230 EEPVVLALAEKYGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQL 289
Query: 113 NQFNKNHRVI 84
N NKN R I
Sbjct: 290 NALNKNWRYI 299
>BT007003-1|AAP35649.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 138 bits (335), Expect = 1e-32
Identities = 74/190 (38%), Positives = 109/190 (57%), Gaps = 11/190 (5%)
Frame = -3
Query: 620 YLIHFPIXTKPDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQI 474
YL+H+P + D+P D+ Y ETW+ ++ GL +++G+SNFN+ QI
Sbjct: 110 YLMHWPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQI 169
Query: 473 TRLVSNSYIRPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPPRS 294
++S + +RP + Q+E +P Q L+AHCQ+ G+ V AYSP G + P
Sbjct: 170 DDILSVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLL 229
Query: 293 DDPTLTALANKYRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAI 114
++P + ALA KY +S QILLR+ + R +I IPKS RI QNI +FDF + EE+ +
Sbjct: 230 EEPVVLALAEKYGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQL 289
Query: 113 NQFNKNHRVI 84
N NKN R I
Sbjct: 290 NALNKNWRYI 299
>BC005394-1|AAH05394.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 138 bits (335), Expect = 1e-32
Identities = 74/190 (38%), Positives = 109/190 (57%), Gaps = 11/190 (5%)
Frame = -3
Query: 620 YLIHFPIXTKPDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQI 474
YL+H+P + D+P D+ Y ETW+ ++ GL +++G+SNFN+ QI
Sbjct: 110 YLMHWPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQI 169
Query: 473 TRLVSNSYIRPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPPRS 294
++S + +RP + Q+E +P Q L+AHCQ+ G+ V AYSP G + P
Sbjct: 170 DDILSVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLL 229
Query: 293 DDPTLTALANKYRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAI 114
++P + ALA KY +S QILLR+ + R +I IPKS RI QNI +FDF + EE+ +
Sbjct: 230 EEPVVLALAEKYGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQL 289
Query: 113 NQFNKNHRVI 84
N NKN R I
Sbjct: 290 NALNKNWRYI 299
>BC000670-1|AAH00670.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 138 bits (335), Expect = 1e-32
Identities = 74/190 (38%), Positives = 109/190 (57%), Gaps = 11/190 (5%)
Frame = -3
Query: 620 YLIHFPIXTKPDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQI 474
YL+H+P + D+P D+ Y ETW+ ++ GL +++G+SNFN+ QI
Sbjct: 110 YLMHWPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQI 169
Query: 473 TRLVSNSYIRPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPPRS 294
++S + +RP + Q+E +P Q L+AHCQ+ G+ V AYSP G + P
Sbjct: 170 DDILSVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLL 229
Query: 293 DDPTLTALANKYRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAI 114
++P + ALA KY +S QILLR+ + R +I IPKS RI QNI +FDF + EE+ +
Sbjct: 230 EEPVVLALAEKYGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQL 289
Query: 113 NQFNKNHRVI 84
N NKN R I
Sbjct: 290 NALNKNWRYI 299
>AL355480-3|CAI22459.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehydetase, 1 protein.
Length = 325
Score = 138 bits (335), Expect = 1e-32
Identities = 74/190 (38%), Positives = 109/190 (57%), Gaps = 11/190 (5%)
Frame = -3
Query: 620 YLIHFPIXTKPDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQI 474
YL+H+P + D+P D+ Y ETW+ ++ GL +++G+SNFN+ QI
Sbjct: 110 YLMHWPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQI 169
Query: 473 TRLVSNSYIRPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPPRS 294
++S + +RP + Q+E +P Q L+AHCQ+ G+ V AYSP G + P
Sbjct: 170 DDILSVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLL 229
Query: 293 DDPTLTALANKYRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAI 114
++P + ALA KY +S QILLR+ + R +I IPKS RI QNI +FDF + EE+ +
Sbjct: 230 EEPVVLALAEKYGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQL 289
Query: 113 NQFNKNHRVI 84
N NKN R I
Sbjct: 290 NALNKNWRYI 299
>AF112485-1|AAF01260.1| 325|Homo sapiens aldehyde reductase
protein.
Length = 325
Score = 138 bits (335), Expect = 1e-32
Identities = 74/190 (38%), Positives = 109/190 (57%), Gaps = 11/190 (5%)
Frame = -3
Query: 620 YLIHFPIXTKPDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQI 474
YL+H+P + D+P D+ Y ETW+ ++ GL +++G+SNFN+ QI
Sbjct: 110 YLMHWPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQI 169
Query: 473 TRLVSNSYIRPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPPRS 294
++S + +RP + Q+E +P Q L+AHCQ+ G+ V AYSP G + P
Sbjct: 170 DDILSVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLL 229
Query: 293 DDPTLTALANKYRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAI 114
++P + ALA KY +S QILLR+ + R +I IPKS RI QNI +FDF + EE+ +
Sbjct: 230 EEPVVLALAEKYGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQL 289
Query: 113 NQFNKNHRVI 84
N NKN R I
Sbjct: 290 NALNKNWRYI 299
>AF036683-1|AAB92369.1| 325|Homo sapiens aldehyde reductase
protein.
Length = 325
Score = 138 bits (335), Expect = 1e-32
Identities = 74/190 (38%), Positives = 109/190 (57%), Gaps = 11/190 (5%)
Frame = -3
Query: 620 YLIHFPIXTKPDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQI 474
YL+H+P + D+P D+ Y ETW+ ++ GL +++G+SNFN+ QI
Sbjct: 110 YLMHWPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQI 169
Query: 473 TRLVSNSYIRPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPPRS 294
++S + +RP + Q+E +P Q L+AHCQ+ G+ V AYSP G + P
Sbjct: 170 DDILSVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLL 229
Query: 293 DDPTLTALANKYRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAI 114
++P + ALA KY +S QILLR+ + R +I IPKS RI QNI +FDF + EE+ +
Sbjct: 230 EEPVVLALAEKYGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQL 289
Query: 113 NQFNKNHRVI 84
N NKN R I
Sbjct: 290 NALNKNWRYI 299
>U37100-1|AAC17469.1| 316|Homo sapiens aldose reductase-like
peptide protein.
Length = 316
Score = 138 bits (333), Expect = 2e-32
Identities = 79/204 (38%), Positives = 116/204 (56%), Gaps = 16/204 (7%)
Frame = -3
Query: 620 YLIHFPIXTK------PDDSPDNI-----DYLETWQGMQDARQLGLARSIGVSNFNATQI 474
YLIH+P K P D N +L+ W+ M++ GL +++GVSNF+ QI
Sbjct: 108 YLIHWPQGFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQI 167
Query: 473 TRLVSNSYIR--PVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPP 300
+L++ ++ PV NQ+E +P TQE L+ +C S GI V AYSP G P
Sbjct: 168 EKLLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPS 227
Query: 299 RSDDPTLTALANKYRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEVA 120
+DP + +A K++K+ Q+L+R+ I R +I IPKS RI +NI +FDF+L+ EE+A
Sbjct: 228 LLEDPKIKEIAAKHKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMA 287
Query: 119 AINQFNKNHR---VIDISDWKDYP 57
I FN+N R V+ S +DYP
Sbjct: 288 TILSFNRNWRACNVLQSSHLEDYP 311
>CR541801-1|CAG46600.1| 316|Homo sapiens AKR1B10 protein.
Length = 316
Score = 138 bits (333), Expect = 2e-32
Identities = 79/204 (38%), Positives = 116/204 (56%), Gaps = 16/204 (7%)
Frame = -3
Query: 620 YLIHFPIXTK------PDDSPDNI-----DYLETWQGMQDARQLGLARSIGVSNFNATQI 474
YLIH+P K P D N +L+ W+ M++ GL +++GVSNF+ QI
Sbjct: 108 YLIHWPQGFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQI 167
Query: 473 TRLVSNSYIR--PVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPP 300
+L++ ++ PV NQ+E +P TQE L+ +C S GI V AYSP G P
Sbjct: 168 EKLLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPS 227
Query: 299 RSDDPTLTALANKYRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEVA 120
+DP + +A K++K+ Q+L+R+ I R +I IPKS RI +NI +FDF+L+ EE+A
Sbjct: 228 LLEDPKIKEIAAKHKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMA 287
Query: 119 AINQFNKNHR---VIDISDWKDYP 57
I FN+N R V+ S +DYP
Sbjct: 288 TILSFNRNWRACNVLQSSHLEDYP 311
>BT006794-1|AAP35440.1| 316|Homo sapiens aldo-keto reductase family
1, member B10 (aldose reductase) protein.
Length = 316
Score = 138 bits (333), Expect = 2e-32
Identities = 79/204 (38%), Positives = 116/204 (56%), Gaps = 16/204 (7%)
Frame = -3
Query: 620 YLIHFPIXTK------PDDSPDNI-----DYLETWQGMQDARQLGLARSIGVSNFNATQI 474
YLIH+P K P D N +L+ W+ M++ GL +++GVSNF+ QI
Sbjct: 108 YLIHWPQGFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQI 167
Query: 473 TRLVSNSYIR--PVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPP 300
+L++ ++ PV NQ+E +P TQE L+ +C S GI V AYSP G P
Sbjct: 168 EKLLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPS 227
Query: 299 RSDDPTLTALANKYRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEVA 120
+DP + +A K++K+ Q+L+R+ I R +I IPKS RI +NI +FDF+L+ EE+A
Sbjct: 228 LLEDPKIKEIAAKHKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMA 287
Query: 119 AINQFNKNHR---VIDISDWKDYP 57
I FN+N R V+ S +DYP
Sbjct: 288 TILSFNRNWRACNVLQSSHLEDYP 311
>BC008837-1|AAH08837.1| 316|Homo sapiens aldo-keto reductase family
1, member B10 (aldose reductase) protein.
Length = 316
Score = 138 bits (333), Expect = 2e-32
Identities = 79/204 (38%), Positives = 116/204 (56%), Gaps = 16/204 (7%)
Frame = -3
Query: 620 YLIHFPIXTK------PDDSPDNI-----DYLETWQGMQDARQLGLARSIGVSNFNATQI 474
YLIH+P K P D N +L+ W+ M++ GL +++GVSNF+ QI
Sbjct: 108 YLIHWPQGFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQI 167
Query: 473 TRLVSNSYIR--PVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPP 300
+L++ ++ PV NQ+E +P TQE L+ +C S GI V AYSP G P
Sbjct: 168 EKLLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPS 227
Query: 299 RSDDPTLTALANKYRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEVA 120
+DP + +A K++K+ Q+L+R+ I R +I IPKS RI +NI +FDF+L+ EE+A
Sbjct: 228 LLEDPKIKEIAAKHKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMA 287
Query: 119 AINQFNKNHR---VIDISDWKDYP 57
I FN+N R V+ S +DYP
Sbjct: 288 TILSFNRNWRACNVLQSSHLEDYP 311
>BC005387-1|AAH05387.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 138 bits (333), Expect = 2e-32
Identities = 75/204 (36%), Positives = 118/204 (57%), Gaps = 16/204 (7%)
Frame = -3
Query: 620 YLIHFPIXTKP-------DDS----PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQI 474
YLIH+P KP D+S P + + L+T M++ GL ++IG+SNFN Q+
Sbjct: 108 YLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTRAAMEELVDEGLVKAIGISNFNHLQV 167
Query: 473 TRLVSNSYIR--PVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPP 300
+++ ++ P +NQIE +P TQE L+ +CQS GI V AYSP G P
Sbjct: 168 EMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPS 227
Query: 299 RSDDPTLTALANKYRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEVA 120
+DP + A+A K+ K+ Q+L+R+ + R L+ IPKS +RIA+N +FDF+L+ +++
Sbjct: 228 LLEDPRIKAIAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMT 287
Query: 119 AINQFNKNHRV---IDISDWKDYP 57
+ +N+N RV + + KDYP
Sbjct: 288 TLLSYNRNWRVCALLSCTSHKDYP 311
>AF052577-1|AAC36465.1| 316|Homo sapiens aldo-keto reductase
protein.
Length = 316
Score = 138 bits (333), Expect = 2e-32
Identities = 79/204 (38%), Positives = 116/204 (56%), Gaps = 16/204 (7%)
Frame = -3
Query: 620 YLIHFPIXTK------PDDSPDNI-----DYLETWQGMQDARQLGLARSIGVSNFNATQI 474
YLIH+P K P D N +L+ W+ M++ GL +++GVSNF+ QI
Sbjct: 108 YLIHWPQGFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQI 167
Query: 473 TRLVSNSYIR--PVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPP 300
+L++ ++ PV NQ+E +P TQE L+ +C S GI V AYSP G P
Sbjct: 168 EKLLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPS 227
Query: 299 RSDDPTLTALANKYRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEVA 120
+DP + +A K++K+ Q+L+R+ I R +I IPKS RI +NI +FDF+L+ EE+A
Sbjct: 228 LLEDPKIKEIAAKHKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMA 287
Query: 119 AINQFNKNHR---VIDISDWKDYP 57
I FN+N R V+ S +DYP
Sbjct: 288 TILSFNRNWRACNVLQSSHLEDYP 311
>AF524864-1|AAO13380.1| 316|Homo sapiens aldo-ketoreductase
protein.
Length = 316
Score = 137 bits (332), Expect = 3e-32
Identities = 79/204 (38%), Positives = 116/204 (56%), Gaps = 16/204 (7%)
Frame = -3
Query: 620 YLIHFPIXTK------PDDSPDNI-----DYLETWQGMQDARQLGLARSIGVSNFNATQI 474
YLIH+P K P D N +L+ W+ M++ GL +++GVSNF+ QI
Sbjct: 108 YLIHWPQGFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQI 167
Query: 473 TRLVSNSYIR--PVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPP 300
+L++ ++ PV NQ+E +P TQE L+ +C S GI V AYSP G P
Sbjct: 168 EKLLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPS 227
Query: 299 RSDDPTLTALANKYRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEVA 120
+DP + +A K++K+ Q+L+R+ I R +I IPKS RI +NI +FDF+L+ EE+A
Sbjct: 228 LLEDPKIKEIAAKHKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMA 287
Query: 119 AINQFNKNHR---VIDISDWKDYP 57
I FN+N R V+ S +DYP
Sbjct: 288 IILSFNRNWRACNVLQSSHLEDYP 311
>D17793-1|BAA04619.2| 325|Homo sapiens KIAA0119 protein.
Length = 325
Score = 136 bits (330), Expect = 4e-32
Identities = 75/205 (36%), Positives = 117/205 (57%), Gaps = 14/205 (6%)
Frame = -3
Query: 620 YLIHFPIXTKPDD--SP---------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQI 474
YLIH P+ KP + SP D +D TW+ M+ + GLA+SIGVSNFN Q+
Sbjct: 116 YLIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQL 175
Query: 473 TRLVSNSYIR--PVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPP 300
+++ ++ PV NQ+E +P + L+ C+S I ++AYS G + P
Sbjct: 176 EMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSP 235
Query: 299 -RSDDPTLTALANKYRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEV 123
+DP L ALA K++++ I LRY + RG++ + KS N+QRI QN+ +F+FQLT E++
Sbjct: 236 VLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDM 295
Query: 122 AAINQFNKNHRVIDISDWKDYPNYP 48
AI+ ++N + + +PNYP
Sbjct: 296 KAIDGLDRNLHYFNSDSFASHPNYP 320
>DQ269985-1|ABB76132.1| 323|Homo sapiens type II 3a-hydroxysteroid
dehydrogenase variant protein.
Length = 323
Score = 136 bits (330), Expect = 4e-32
Identities = 75/205 (36%), Positives = 117/205 (57%), Gaps = 14/205 (6%)
Frame = -3
Query: 620 YLIHFPIXTKPDD--SP---------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQI 474
YLIH P+ KP + SP D +D TW+ M+ + GLA+SIGVSNFN Q+
Sbjct: 114 YLIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQL 173
Query: 473 TRLVSNSYIR--PVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPP 300
+++ ++ PV NQ+E +P + L+ C+S I ++AYS G + P
Sbjct: 174 EMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSP 233
Query: 299 -RSDDPTLTALANKYRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEV 123
+DP L ALA K++++ I LRY + RG++ + KS N+QRI QN+ +F+FQLT E++
Sbjct: 234 VLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDM 293
Query: 122 AAINQFNKNHRVIDISDWKDYPNYP 48
AI+ ++N + + +PNYP
Sbjct: 294 KAIDGLDRNLHYFNSDSFASHPNYP 318
>BT007286-1|AAP35950.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 136 bits (330), Expect = 4e-32
Identities = 75/205 (36%), Positives = 117/205 (57%), Gaps = 14/205 (6%)
Frame = -3
Query: 620 YLIHFPIXTKPDD--SP---------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQI 474
YLIH P+ KP + SP D +D TW+ M+ + GLA+SIGVSNFN Q+
Sbjct: 114 YLIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQL 173
Query: 473 TRLVSNSYIR--PVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPP 300
+++ ++ PV NQ+E +P + L+ C+S I ++AYS G + P
Sbjct: 174 EMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSP 233
Query: 299 -RSDDPTLTALANKYRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEV 123
+DP L ALA K++++ I LRY + RG++ + KS N+QRI QN+ +F+FQLT E++
Sbjct: 234 VLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDM 293
Query: 122 AAINQFNKNHRVIDISDWKDYPNYP 48
AI+ ++N + + +PNYP
Sbjct: 294 KAIDGLDRNLHYFNSDSFASHPNYP 318
>BC019230-1|AAH19230.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 136 bits (330), Expect = 4e-32
Identities = 75/205 (36%), Positives = 117/205 (57%), Gaps = 14/205 (6%)
Frame = -3
Query: 620 YLIHFPIXTKPDD--SP---------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQI 474
YLIH P+ KP + SP D +D TW+ M+ + GLA+SIGVSNFN Q+
Sbjct: 114 YLIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQL 173
Query: 473 TRLVSNSYIR--PVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPP 300
+++ ++ PV NQ+E +P + L+ C+S I ++AYS G + P
Sbjct: 174 EMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSP 233
Query: 299 -RSDDPTLTALANKYRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEV 123
+DP L ALA K++++ I LRY + RG++ + KS N+QRI QN+ +F+FQLT E++
Sbjct: 234 VLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDM 293
Query: 122 AAINQFNKNHRVIDISDWKDYPNYP 48
AI+ ++N + + +PNYP
Sbjct: 294 KAIDGLDRNLHYFNSDSFASHPNYP 318
>BC001479-1|AAH01479.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 136 bits (330), Expect = 4e-32
Identities = 75/205 (36%), Positives = 117/205 (57%), Gaps = 14/205 (6%)
Frame = -3
Query: 620 YLIHFPIXTKPDD--SP---------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQI 474
YLIH P+ KP + SP D +D TW+ M+ + GLA+SIGVSNFN Q+
Sbjct: 114 YLIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQL 173
Query: 473 TRLVSNSYIR--PVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPP 300
+++ ++ PV NQ+E +P + L+ C+S I ++AYS G + P
Sbjct: 174 EMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSP 233
Query: 299 -RSDDPTLTALANKYRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEV 123
+DP L ALA K++++ I LRY + RG++ + KS N+QRI QN+ +F+FQLT E++
Sbjct: 234 VLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDM 293
Query: 122 AAINQFNKNHRVIDISDWKDYPNYP 48
AI+ ++N + + +PNYP
Sbjct: 294 KAIDGLDRNLHYFNSDSFASHPNYP 318
>AL391427-4|CAI14729.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 136 bits (330), Expect = 4e-32
Identities = 75/205 (36%), Positives = 117/205 (57%), Gaps = 14/205 (6%)
Frame = -3
Query: 620 YLIHFPIXTKPDD--SP---------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQI 474
YLIH P+ KP + SP D +D TW+ M+ + GLA+SIGVSNFN Q+
Sbjct: 114 YLIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQL 173
Query: 473 TRLVSNSYIR--PVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPP 300
+++ ++ PV NQ+E +P + L+ C+S I ++AYS G + P
Sbjct: 174 EMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSP 233
Query: 299 -RSDDPTLTALANKYRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEV 123
+DP L ALA K++++ I LRY + RG++ + KS N+QRI QN+ +F+FQLT E++
Sbjct: 234 VLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDM 293
Query: 122 AAINQFNKNHRVIDISDWKDYPNYP 48
AI+ ++N + + +PNYP
Sbjct: 294 KAIDGLDRNLHYFNSDSFASHPNYP 318
>AB032157-1|BAA92892.1| 323|Homo sapiens prostaglandin F synthase
protein.
Length = 323
Score = 136 bits (330), Expect = 4e-32
Identities = 75/205 (36%), Positives = 117/205 (57%), Gaps = 14/205 (6%)
Frame = -3
Query: 620 YLIHFPIXTKPDD--SP---------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQI 474
YLIH P+ KP + SP D +D TW+ M+ + GLA+SIGVSNFN Q+
Sbjct: 114 YLIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQL 173
Query: 473 TRLVSNSYIR--PVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPP 300
+++ ++ PV NQ+E +P + L+ C+S I ++AYS G + P
Sbjct: 174 EMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSP 233
Query: 299 -RSDDPTLTALANKYRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEV 123
+DP L ALA K++++ I LRY + RG++ + KS N+QRI QN+ +F+FQLT E++
Sbjct: 234 VLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDM 293
Query: 122 AAINQFNKNHRVIDISDWKDYPNYP 48
AI+ ++N + + +PNYP
Sbjct: 294 KAIDGLDRNLHYFNSDSFASHPNYP 318
>AB018580-1|BAA88488.1| 323|Homo sapiens hluPGFS protein.
Length = 323
Score = 136 bits (330), Expect = 4e-32
Identities = 75/205 (36%), Positives = 117/205 (57%), Gaps = 14/205 (6%)
Frame = -3
Query: 620 YLIHFPIXTKPDD--SP---------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQI 474
YLIH P+ KP + SP D +D TW+ M+ + GLA+SIGVSNFN Q+
Sbjct: 114 YLIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQL 173
Query: 473 TRLVSNSYIR--PVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPP 300
+++ ++ PV NQ+E +P + L+ C+S I ++AYS G + P
Sbjct: 174 EMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSP 233
Query: 299 -RSDDPTLTALANKYRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEV 123
+DP L ALA K++++ I LRY + RG++ + KS N+QRI QN+ +F+FQLT E++
Sbjct: 234 VLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDM 293
Query: 122 AAINQFNKNHRVIDISDWKDYPNYP 48
AI+ ++N + + +PNYP
Sbjct: 294 KAIDGLDRNLHYFNSDSFASHPNYP 318
>S68288-1|AAD14011.1| 323|Homo sapiens chlordecone reductase
homolog protein.
Length = 323
Score = 136 bits (328), Expect = 8e-32
Identities = 75/205 (36%), Positives = 117/205 (57%), Gaps = 14/205 (6%)
Frame = -3
Query: 620 YLIHFPIXTKPDD--SP---------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQI 474
YLIH P+ KP + SP D +D TW+ M+ + GLA+SIGVSNFN Q+
Sbjct: 114 YLIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQL 173
Query: 473 TRLVSNSYIR--PVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPP 300
+++ ++ PV NQ+E +P + L+ C+S I ++AYS G + P
Sbjct: 174 EIILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSP 233
Query: 299 -RSDDPTLTALANKYRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEV 123
+DP L ALA K++++ I LRY + RG++ + KS N+QRI QN+ +F+FQLT E++
Sbjct: 234 VLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDM 293
Query: 122 AAINQFNKNHRVIDISDWKDYPNYP 48
AI+ ++N + + +PNYP
Sbjct: 294 KAIDGLDRNLHYFNSDSFASHPNYP 318
>L43839-1|AAB41916.1| 323|Homo sapiens 3-alpha-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 136 bits (328), Expect = 8e-32
Identities = 75/205 (36%), Positives = 117/205 (57%), Gaps = 14/205 (6%)
Frame = -3
Query: 620 YLIHFPIXTKPDD--SP---------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQI 474
YLIH P+ KP + SP D +D TW+ M+ + GLA+SIGVSNFN Q+
Sbjct: 114 YLIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQL 173
Query: 473 TRLVSNSYIR--PVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPP 300
+++ ++ PV NQ+E +P + L+ C+S I ++AYS G + P
Sbjct: 174 EIILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSP 233
Query: 299 -RSDDPTLTALANKYRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEV 123
+DP L ALA K++++ I LRY + RG++ + KS N+QRI QN+ +F+FQLT E++
Sbjct: 234 VLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDM 293
Query: 122 AAINQFNKNHRVIDISDWKDYPNYP 48
AI+ ++N + + +PNYP
Sbjct: 294 KAIDGLDRNLHYFNSDSFASHPNYP 318
>AF149416-1|AAF07272.2| 323|Homo sapiens 3-alpha hydroxysteroid
dehydrogenase type IIb protein.
Length = 323
Score = 135 bits (327), Expect = 1e-31
Identities = 74/205 (36%), Positives = 117/205 (57%), Gaps = 14/205 (6%)
Frame = -3
Query: 620 YLIHFPIXTKPDD--SP---------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQI 474
YLIH P+ KP + SP D +D TW+ M+ + GLA+SIGVSNFN Q+
Sbjct: 114 YLIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQL 173
Query: 473 TRLVSNSYIR--PVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPP 300
+++ ++ PV NQ+E +P + L+ C+S I ++AYS G + P
Sbjct: 174 EMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSP 233
Query: 299 -RSDDPTLTALANKYRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEV 123
+DP L ALA K++++ I LRY + RG++ + +S N+QRI QN+ +F+FQLT E++
Sbjct: 234 VLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLARSYNEQRIRQNVQVFEFQLTAEDM 293
Query: 122 AAINQFNKNHRVIDISDWKDYPNYP 48
AI+ ++N + + +PNYP
Sbjct: 294 KAIDGLDRNLHYFNSDSFASHPNYP 318
>AF263242-1|AAK58523.1| 320|Homo sapiens aldo-keto reductase
loopADR protein.
Length = 320
Score = 123 bits (296), Expect = 6e-28
Identities = 68/179 (37%), Positives = 104/179 (58%), Gaps = 2/179 (1%)
Frame = -3
Query: 578 PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR--PVINQIEVNPTNT 405
P + D+L+TW+ M+D GL ++IGVSNFN Q+ RL++ +R P+ NQIE +P T
Sbjct: 143 PSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIECHPYLT 202
Query: 404 QEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPPRSDDPTLTALANKYRKSVGQILLRY 225
Q+ L++ CQS ++V AY P G G D+P + +A ++ KS QIL+R+
Sbjct: 203 QKNLISFCQSRDVSVTAYRPLG-----GSCEGVD-LIDNPVIKRIAKEHGKSPAQILIRF 256
Query: 224 LIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKNHRVIDISDWKDYPNYP 48
I R +I IP S I +NI +FDF+LT ++ I N+N R+ K++ +YP
Sbjct: 257 QIQRNVIVIPGSITPSHIKENIQVFDFELTQHDMDNILSLNRNLRLAMFPITKNHNDYP 315
>BC002862-1|AAH02862.1| 307|Homo sapiens AKR1CL2 protein protein.
Length = 307
Score = 118 bits (285), Expect = 1e-26
Identities = 65/166 (39%), Positives = 98/166 (59%), Gaps = 2/166 (1%)
Frame = -3
Query: 578 PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR--PVINQIEVNPTNT 405
P + D+L+TW+ M+D GL ++IGVSNFN Q+ RL++ +R P+ NQIE +P T
Sbjct: 143 PSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIECHPYLT 202
Query: 404 QEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPPRSDDPTLTALANKYRKSVGQILLRY 225
Q+ L++ CQS ++V AY P G G D+P + +A ++ KS QIL+R+
Sbjct: 203 QKNLISFCQSRDVSVTAYRPLG-----GSCEGVD-LIDNPVIKRIAKEHGKSPAQILIRF 256
Query: 224 LIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKNHRV 87
I R +I IP S I +NI +FDF+LT ++ I N+N R+
Sbjct: 257 QIQRNVIVIPGSITPSHIKENIQVFDFELTQHDMDNILSLNRNLRL 302
>AB055603-1|BAC54568.1| 307|Homo sapiens aldo-keto reductase
related protein 4 protein.
Length = 307
Score = 118 bits (285), Expect = 1e-26
Identities = 65/166 (39%), Positives = 98/166 (59%), Gaps = 2/166 (1%)
Frame = -3
Query: 578 PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR--PVINQIEVNPTNT 405
P + D+L+TW+ M+D GL ++IGVSNFN Q+ RL++ +R P+ NQIE +P T
Sbjct: 143 PSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIECHPYLT 202
Query: 404 QEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPPRSDDPTLTALANKYRKSVGQILLRY 225
Q+ L++ CQS ++V AY P G G D+P + +A ++ KS QIL+R+
Sbjct: 203 QKNLISFCQSRDVSVTAYRPLG-----GSCEGVD-LIDNPVIKRIAKEHGKSPAQILIRF 256
Query: 224 LIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKNHRV 87
I R +I IP S I +NI +FDF+LT ++ I N+N R+
Sbjct: 257 QIQRNVIVIPGSITPSHIKENIQVFDFELTQHDMDNILSLNRNLRL 302
>AL713867-3|CAI16410.1| 247|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 247
Score = 109 bits (263), Expect = 6e-24
Identities = 61/168 (36%), Positives = 92/168 (54%), Gaps = 14/168 (8%)
Frame = -3
Query: 620 YLIHFPIXTKPDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQI 474
YLIHFP+ KP + D +D TW+ ++ + GLA+SIGVSNFN Q+
Sbjct: 80 YLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQL 139
Query: 473 TRLVSNSYIR--PVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPP 300
+++ ++ PV NQ+E +P Q L+ C+S I ++AYS G P
Sbjct: 140 EMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSP 199
Query: 299 -RSDDPTLTALANKYRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNI 159
+DP L ALA K++++ I LRY + RG++ + KS N+QRI QN+
Sbjct: 200 VLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNV 247
>AB209796-1|BAD93033.1| 260|Homo sapiens aldo-keto reductase family
1, member B1 variant protein.
Length = 260
Score = 93.5 bits (222), Expect = 5e-19
Identities = 52/141 (36%), Positives = 78/141 (55%), Gaps = 13/141 (9%)
Frame = -3
Query: 620 YLIHFPIXTKP-------DDS----PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQI 474
YLIH+P KP D+S P + + L+TW M++ GL ++IG+SNFN Q+
Sbjct: 105 YLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQV 164
Query: 473 TRLVSNSYIR--PVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPP 300
+++ ++ P +NQIE +P TQE L+ +CQS GI V AYSP G P
Sbjct: 165 EMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPS 224
Query: 299 RSDDPTLTALANKYRKSVGQI 237
+DP + A+A K+ K+ Q+
Sbjct: 225 LLEDPRIKAIAAKHNKTTAQV 245
>AL391427-2|CAI14727.1| 302|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 302
Score = 83.0 bits (196), Expect = 8e-16
Identities = 44/132 (33%), Positives = 76/132 (57%), Gaps = 2/132 (1%)
Frame = -3
Query: 446 RPVINQI-EVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPPRS-DDPTLTA 273
+P NQ+ E +P Q L+ C+S I ++AYS G P ++P L +
Sbjct: 166 KPTCNQVVECHPYLNQSKLLEFCKSKDIVLVAYSALGSQRDPQWVDPDCPHLLEEPILKS 225
Query: 272 LANKYRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKNH 93
+A K+ +S GQ+ LRY + RG++ + KS +++RI +N +FDF+LT E++ AI+ N+N
Sbjct: 226 IAKKHSRSPGQVALRYQLQRGVVVLAKSFSQERIKENFQIFDFELTPEDMKAIDGLNRNL 285
Query: 92 RVIDISDWKDYP 57
R + ++ +P
Sbjct: 286 RYDNAANHPYFP 297
>AL355303-1|CAI14201.1| 302|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 302
Score = 83.0 bits (196), Expect = 8e-16
Identities = 44/132 (33%), Positives = 76/132 (57%), Gaps = 2/132 (1%)
Frame = -3
Query: 446 RPVINQI-EVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPPRS-DDPTLTA 273
+P NQ+ E +P Q L+ C+S I ++AYS G P ++P L +
Sbjct: 166 KPTCNQVVECHPYLNQSKLLEFCKSKDIVLVAYSALGSQRDPQWVDPDCPHLLEEPILKS 225
Query: 272 LANKYRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKNH 93
+A K+ +S GQ+ LRY + RG++ + KS +++RI +N +FDF+LT E++ AI+ N+N
Sbjct: 226 IAKKHSRSPGQVALRYQLQRGVVVLAKSFSQERIKENFQIFDFELTPEDMKAIDGLNRNL 285
Query: 92 RVIDISDWKDYP 57
R + ++ +P
Sbjct: 286 RYDNAANHPYFP 297
>AB209017-1|BAD92254.1| 286|Homo sapiens aldo-keto reductase family
1, member C2 variant protein.
Length = 286
Score = 77.4 bits (182), Expect = 4e-14
Identities = 47/134 (35%), Positives = 67/134 (50%), Gaps = 14/134 (10%)
Frame = -3
Query: 620 YLIHFPIXTKPDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQI 474
YLIHFP+ KP + D +D TW+ M+ + GLA+SIGVSNFN +
Sbjct: 127 YLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLL 186
Query: 473 TRLVSNSYI--RPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGA-PP 303
+++ + +PV NQ+E +P Q L+ C+S I ++AYS G P
Sbjct: 187 EMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSP 246
Query: 302 PRSDDPTLTALANK 261
+DP L ALA K
Sbjct: 247 VLLEDPVLCALAKK 260
>AF044961-1|AAC15671.1| 85|Homo sapiens aldose reductase-related
protein protein.
Length = 85
Score = 71.3 bits (167), Expect = 3e-12
Identities = 35/80 (43%), Positives = 52/80 (65%), Gaps = 3/80 (3%)
Frame = -3
Query: 287 PTLTALANKYRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQ 108
P + +A K++K+ Q+L+R+ I R +I IPKS RI +NI +FDF+L+ EE+A I
Sbjct: 1 PKIKEIAAKHKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILS 60
Query: 107 FNKNHR---VIDISDWKDYP 57
FN+N R V+ S +DYP
Sbjct: 61 FNRNWRACNVLQSSHLEDYP 80
>AK058142-1|BAB71682.1| 146|Homo sapiens protein ( Homo sapiens
cDNA FLJ25413 fis, clone TST03402, highly similar to
3-OXO-5-BETA-STEROID 4-DEHYDROGENASE (EC 1.3.99.6). ).
Length = 146
Score = 65.3 bits (152), Expect = 2e-10
Identities = 30/74 (40%), Positives = 45/74 (60%), Gaps = 2/74 (2%)
Frame = -3
Query: 554 TWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR--PVINQIEVNPTNTQEPLVAHC 381
TW+ M+ + GL +S+GVSNFN Q+ +++ ++ PV NQ+E +P TQ L+ C
Sbjct: 28 TWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKPVSNQVECHPYFTQPKLLKFC 87
Query: 380 QSLGIAVMAYSPFG 339
Q I + AYSP G
Sbjct: 88 QQHDIVITAYSPLG 101
>AB040821-1|BAC54566.1| 263|Homo sapiens aldo-keto reductase
related protein 2 protein.
Length = 263
Score = 52.4 bits (120), Expect(2) = 6e-07
Identities = 24/53 (45%), Positives = 36/53 (67%), Gaps = 2/53 (3%)
Frame = -3
Query: 578 PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR--PVINQI 426
P + D+L+TW+ M+D GL ++IGVSNFN Q+ RL++ +R P+ NQI
Sbjct: 143 PSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQI 195
Score = 52.0 bits (119), Expect = 2e-06
Identities = 25/72 (34%), Positives = 41/72 (56%)
Frame = -3
Query: 263 KYRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKNHRVI 84
+++ QIL+R+ I R +I IP S I +NI +FDF+LT ++ I N+N R+
Sbjct: 187 RFKPLTNQILIRFQIQRNVIVIPGSITPSHIKENIQVFDFELTQHDMDNILSLNRNLRLA 246
Query: 83 DISDWKDYPNYP 48
K++ +YP
Sbjct: 247 MFPITKNHKDYP 258
Score = 20.6 bits (41), Expect(2) = 6e-07
Identities = 7/11 (63%), Positives = 9/11 (81%)
Frame = -3
Query: 620 YLIHFPIXTKP 588
YLIH+P+ KP
Sbjct: 99 YLIHWPMGFKP 109
>AB040820-1|BAC54565.1| 250|Homo sapiens aldo-keto reductase
related protein 1 protein.
Length = 250
Score = 52.4 bits (120), Expect(2) = 6e-07
Identities = 24/53 (45%), Positives = 36/53 (67%), Gaps = 2/53 (3%)
Frame = -3
Query: 578 PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR--PVINQI 426
P + D+L+TW+ M+D GL ++IGVSNFN Q+ RL++ +R P+ NQI
Sbjct: 143 PSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQI 195
Score = 47.2 bits (107), Expect = 5e-05
Identities = 22/59 (37%), Positives = 35/59 (59%)
Frame = -3
Query: 263 KYRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKNHRV 87
+++ QIL+R+ I R +I IP S I +NI +FDF+LT ++ I N+N R+
Sbjct: 187 RFKPLTNQILIRFQIQRNVIVIPGSITPSHIKENIQVFDFELTQHDMDNILSLNRNLRL 245
Score = 20.6 bits (41), Expect(2) = 6e-07
Identities = 7/11 (63%), Positives = 9/11 (81%)
Frame = -3
Query: 620 YLIHFPIXTKP 588
YLIH+P+ KP
Sbjct: 99 YLIHWPMGFKP 109
>AB040822-1|BAC54567.1| 222|Homo sapiens aldo-keto reductase
related protein 3 protein.
Length = 222
Score = 49.2 bits (112), Expect = 1e-05
Identities = 24/65 (36%), Positives = 38/65 (58%)
Frame = -3
Query: 242 QILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKNHRVIDISDWKD 63
+IL+R+ I R +I IP S I +NI +FDF+LT ++ I N+N R+ K+
Sbjct: 153 EILIRFQIQRNVIVIPGSITPSHIKENIQVFDFELTQHDMDNILSLNRNLRLAMFPITKN 212
Query: 62 YPNYP 48
+ +YP
Sbjct: 213 HKDYP 217
>AB028065-1|BAA88489.1| 67|Homo sapiens prostaglandin F synthase
protein.
Length = 67
Score = 46.4 bits (105), Expect = 8e-05
Identities = 21/51 (41%), Positives = 32/51 (62%), Gaps = 2/51 (3%)
Frame = -3
Query: 575 DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI--RPVINQ 429
D +D TW+ M+ + GLA+SIGVSNFN Q+ +++ + +PV NQ
Sbjct: 17 DIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQ 67
>AK025747-1|BAB15231.1| 171|Homo sapiens protein ( Homo sapiens
cDNA: FLJ22094 fis, clone HEP16856. ).
Length = 171
Score = 32.7 bits (71), Expect = 1.1
Identities = 20/75 (26%), Positives = 38/75 (50%), Gaps = 1/75 (1%)
Frame = -3
Query: 296 SDDPTLTALANKYRKSVGQILLRYLIDRGLIPIPKSTNK-QRIAQNIDLFDFQLTFEEVA 120
++D + A + + + L RY + R LIP+P ST + Q I Q + ++ L +E A
Sbjct: 32 AEDQIVVICATSKPEEIDESLRRYFMKRLLIPLPDSTARHQIIVQLLSQHNYCLNDKEFA 91
Query: 119 AINQFNKNHRVIDIS 75
+ Q + +D++
Sbjct: 92 LLVQRTEGFSGLDVA 106
>AK001267-1|BAA91590.1| 639|Homo sapiens protein ( Homo sapiens
cDNA FLJ10405 fis, clone NT2RM4000496, weakly similar to
SAP1 PROTEIN. ).
Length = 639
Score = 32.7 bits (71), Expect = 1.1
Identities = 20/75 (26%), Positives = 38/75 (50%), Gaps = 1/75 (1%)
Frame = -3
Query: 296 SDDPTLTALANKYRKSVGQILLRYLIDRGLIPIPKSTNK-QRIAQNIDLFDFQLTFEEVA 120
++D + A + + + L RY + R LIP+P ST + Q I Q + ++ L +E A
Sbjct: 500 AEDQIVVICATSKPEEIDESLRRYFMKRLLIPLPDSTARHQIIVQLLSQHNYCLNDKEFA 559
Query: 119 AINQFNKNHRVIDIS 75
+ Q + +D++
Sbjct: 560 LLVQRTEGFSGLDVA 574
>AC093727-1|AAX81992.1| 639|Homo sapiens unknown protein.
Length = 639
Score = 32.7 bits (71), Expect = 1.1
Identities = 20/75 (26%), Positives = 38/75 (50%), Gaps = 1/75 (1%)
Frame = -3
Query: 296 SDDPTLTALANKYRKSVGQILLRYLIDRGLIPIPKSTNK-QRIAQNIDLFDFQLTFEEVA 120
++D + A + + + L RY + R LIP+P ST + Q I Q + ++ L +E A
Sbjct: 500 AEDQIVVICATSKPEEIDESLRRYFMKRLLIPLPDSTARHQIIVQLLSQHNYCLNDKEFA 559
Query: 119 AINQFNKNHRVIDIS 75
+ Q + +D++
Sbjct: 560 LLVQRTEGFSGLDVA 574
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 95,662,561
Number of Sequences: 237096
Number of extensions: 2151874
Number of successful extensions: 5116
Number of sequences better than 10.0: 91
Number of HSP's better than 10.0 without gapping: 4735
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4918
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 6691573490
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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