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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= fcaL-P12_pT_H15
         (611 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

AF414442-1|AAL65133.2|22152|Homo sapiens ovarian cancer related ...    31   3.2  
BC011571-1|AAH11571.1|  903|Homo sapiens ITCH protein protein.         30   7.4  
AL356299-4|CAI17959.1|  903|Homo sapiens itchy homolog E3 ubiqui...    30   7.4  
AL356299-3|CAI17960.1|  862|Homo sapiens itchy homolog E3 ubiqui...    30   7.4  
AL109923-6|CAI21458.1|  903|Homo sapiens itchy homolog E3 ubiqui...    30   7.4  
AL109923-5|CAI21459.1|  862|Homo sapiens itchy homolog E3 ubiqui...    30   7.4  
AF095745-1|AAK39399.1|  862|Homo sapiens ubiquitin protein ligas...    30   7.4  
AF038564-1|AAC04845.1|  739|Homo sapiens atrophin-1 interacting ...    30   7.4  
AB056663-1|BAB39389.1|  862|Homo sapiens ubiquitin protein ligas...    30   7.4  
AK095631-1|BAC04594.1|  134|Homo sapiens protein ( Homo sapiens ...    25   8.2  
BC110367-1|AAI10368.1| 1047|Homo sapiens chromosome 15 open read...    29   9.8  
BC093825-1|AAH93825.1| 1037|Homo sapiens caspase recruitment dom...    29   9.8  
BC011379-1|AAH11379.2| 1047|Homo sapiens chromosome 15 open read...    29   9.8  
AK128205-1|BAC87324.1| 1047|Homo sapiens protein ( Homo sapiens ...    29   9.8  
AK125604-1|BAC86215.1| 1047|Homo sapiens protein ( Homo sapiens ...    29   9.8  
AF495726-1|AAQ06680.1|  892|Homo sapiens unknown protein.              29   9.8  
AF356193-1|AAK32718.1| 1037|Homo sapiens caspase recruitment dom...    29   9.8  

>AF414442-1|AAL65133.2|22152|Homo sapiens ovarian cancer related tumor
            marker CA125 protein.
          Length = 22152

 Score = 31.1 bits (67), Expect = 3.2
 Identities = 15/42 (35%), Positives = 21/42 (50%)
 Frame = -1

Query: 518  PRPSEPKPTSPARGAPCRSTNEALAETWSQKNQKLSPQVRST 393
            P P+E   TSPA  +P         +  S K   +SP++RST
Sbjct: 3183 PAPAEETGTSPAGTSPGSPEVSTTLKIMSSKEPSISPEIRST 3224


>BC011571-1|AAH11571.1|  903|Homo sapiens ITCH protein protein.
          Length = 903

 Score = 29.9 bits (64), Expect = 7.4
 Identities = 15/44 (34%), Positives = 20/44 (45%)
 Frame = -1

Query: 518 PRPSEPKPTSPARGAPCRSTNEALAETWSQKNQKLSPQVRSTAT 387
           PRPS P P +P R A    +  A +E+       L P   +T T
Sbjct: 254 PRPSRPPPPTPRRPASVNGSPSATSESDGSSTGSLPPTNTNTNT 297


>AL356299-4|CAI17959.1|  903|Homo sapiens itchy homolog E3 ubiquitin
           protein ligase (mouse) protein.
          Length = 903

 Score = 29.9 bits (64), Expect = 7.4
 Identities = 15/44 (34%), Positives = 20/44 (45%)
 Frame = -1

Query: 518 PRPSEPKPTSPARGAPCRSTNEALAETWSQKNQKLSPQVRSTAT 387
           PRPS P P +P R A    +  A +E+       L P   +T T
Sbjct: 254 PRPSRPPPPTPRRPASVNGSPSATSESDGSSTGSLPPTNTNTNT 297


>AL356299-3|CAI17960.1|  862|Homo sapiens itchy homolog E3 ubiquitin
           protein ligase (mouse) protein.
          Length = 862

 Score = 29.9 bits (64), Expect = 7.4
 Identities = 15/44 (34%), Positives = 20/44 (45%)
 Frame = -1

Query: 518 PRPSEPKPTSPARGAPCRSTNEALAETWSQKNQKLSPQVRSTAT 387
           PRPS P P +P R A    +  A +E+       L P   +T T
Sbjct: 213 PRPSRPPPPTPRRPASVNGSPSATSESDGSSTGSLPPTNTNTNT 256


>AL109923-6|CAI21458.1|  903|Homo sapiens itchy homolog E3 ubiquitin
           protein ligase (mouse) protein.
          Length = 903

 Score = 29.9 bits (64), Expect = 7.4
 Identities = 15/44 (34%), Positives = 20/44 (45%)
 Frame = -1

Query: 518 PRPSEPKPTSPARGAPCRSTNEALAETWSQKNQKLSPQVRSTAT 387
           PRPS P P +P R A    +  A +E+       L P   +T T
Sbjct: 254 PRPSRPPPPTPRRPASVNGSPSATSESDGSSTGSLPPTNTNTNT 297


>AL109923-5|CAI21459.1|  862|Homo sapiens itchy homolog E3 ubiquitin
           protein ligase (mouse) protein.
          Length = 862

 Score = 29.9 bits (64), Expect = 7.4
 Identities = 15/44 (34%), Positives = 20/44 (45%)
 Frame = -1

Query: 518 PRPSEPKPTSPARGAPCRSTNEALAETWSQKNQKLSPQVRSTAT 387
           PRPS P P +P R A    +  A +E+       L P   +T T
Sbjct: 213 PRPSRPPPPTPRRPASVNGSPSATSESDGSSTGSLPPTNTNTNT 256


>AF095745-1|AAK39399.1|  862|Homo sapiens ubiquitin protein ligase
           ITCH protein.
          Length = 862

 Score = 29.9 bits (64), Expect = 7.4
 Identities = 15/44 (34%), Positives = 20/44 (45%)
 Frame = -1

Query: 518 PRPSEPKPTSPARGAPCRSTNEALAETWSQKNQKLSPQVRSTAT 387
           PRPS P P +P R A    +  A +E+       L P   +T T
Sbjct: 213 PRPSRPPPPTPRRPASVNGSPSATSESDGSSTGSLPPTNTNTNT 256


>AF038564-1|AAC04845.1|  739|Homo sapiens atrophin-1 interacting
           protein 4 protein.
          Length = 739

 Score = 29.9 bits (64), Expect = 7.4
 Identities = 15/44 (34%), Positives = 20/44 (45%)
 Frame = -1

Query: 518 PRPSEPKPTSPARGAPCRSTNEALAETWSQKNQKLSPQVRSTAT 387
           PRPS P P +P R A    +  A +E+       L P   +T T
Sbjct: 90  PRPSRPPPPTPRRPASVNGSPSATSESDGSSTGSLPPTNTNTNT 133


>AB056663-1|BAB39389.1|  862|Homo sapiens ubiquitin protein ligase
           Itch protein.
          Length = 862

 Score = 29.9 bits (64), Expect = 7.4
 Identities = 15/44 (34%), Positives = 20/44 (45%)
 Frame = -1

Query: 518 PRPSEPKPTSPARGAPCRSTNEALAETWSQKNQKLSPQVRSTAT 387
           PRPS P P +P R A    +  A +E+       L P   +T T
Sbjct: 213 PRPSRPPPPTPRRPASVNGSPSATSESDGSSTGSLPPTNTNTNT 256


>AK095631-1|BAC04594.1|  134|Homo sapiens protein ( Homo sapiens
           cDNA FLJ38312 fis, clone FCBBF3021506. ).
          Length = 134

 Score = 25.4 bits (53), Expect(2) = 8.2
 Identities = 6/11 (54%), Positives = 10/11 (90%)
 Frame = +3

Query: 36  IFACVCVCVCL 68
           +F C+C+CVC+
Sbjct: 84  VFVCMCLCVCI 94



 Score = 23.0 bits (47), Expect(2) = 8.2
 Identities = 7/17 (41%), Positives = 12/17 (70%)
 Frame = +3

Query: 12  HVVXSVFLIFACVCVCV 62
           H+   VF ++ C+CVC+
Sbjct: 53  HMCSCVF-VYVCICVCL 68


>BC110367-1|AAI10368.1| 1047|Homo sapiens chromosome 15 open reading
           frame 39 protein.
          Length = 1047

 Score = 29.5 bits (63), Expect = 9.8
 Identities = 16/51 (31%), Positives = 24/51 (47%), Gaps = 2/51 (3%)
 Frame = -1

Query: 524 ALPRPSEPKPTSPARGAPCRSTNEALAETW--SQKNQKLSPQVRSTATLPV 378
           A  R  +P P S     P R   EA  +TW  S + +KL P++   +  P+
Sbjct: 412 AFQRACQPLPASQPCSEPVRPAQEAEEKTWLPSCRKEKLQPRLSEHSGPPI 462


>BC093825-1|AAH93825.1| 1037|Homo sapiens caspase recruitment domain
            family, member 6 protein.
          Length = 1037

 Score = 29.5 bits (63), Expect = 9.8
 Identities = 16/46 (34%), Positives = 26/46 (56%), Gaps = 3/46 (6%)
 Frame = -1

Query: 509  SEPKPTSPARGAPCRSTNEALAETW---SQKNQKLSPQVRSTATLP 381
            S+P  T P+   PC+ST    ++ W   S+ +Q   PQ +S++T P
Sbjct: 977  SQPSQTKPS---PCKSTQPKPSQPWPPQSKPSQPRPPQPKSSSTNP 1019


>BC011379-1|AAH11379.2| 1047|Homo sapiens chromosome 15 open reading
           frame 39 protein.
          Length = 1047

 Score = 29.5 bits (63), Expect = 9.8
 Identities = 16/51 (31%), Positives = 24/51 (47%), Gaps = 2/51 (3%)
 Frame = -1

Query: 524 ALPRPSEPKPTSPARGAPCRSTNEALAETW--SQKNQKLSPQVRSTATLPV 378
           A  R  +P P S     P R   EA  +TW  S + +KL P++   +  P+
Sbjct: 412 AFQRACQPLPASQPCSEPVRPAQEAEEKTWLPSCRKEKLQPRLSEHSGPPI 462


>AK128205-1|BAC87324.1| 1047|Homo sapiens protein ( Homo sapiens
           cDNA FLJ46337 fis, clone TESTI4046245. ).
          Length = 1047

 Score = 29.5 bits (63), Expect = 9.8
 Identities = 16/51 (31%), Positives = 24/51 (47%), Gaps = 2/51 (3%)
 Frame = -1

Query: 524 ALPRPSEPKPTSPARGAPCRSTNEALAETW--SQKNQKLSPQVRSTATLPV 378
           A  R  +P P S     P R   EA  +TW  S + +KL P++   +  P+
Sbjct: 412 AFQRACQPLPASQPCSEPVRPAQEAEEKTWLPSCRKEKLQPRLSEHSGPPI 462


>AK125604-1|BAC86215.1| 1047|Homo sapiens protein ( Homo sapiens
           cDNA FLJ43616 fis, clone SPLEN2016554. ).
          Length = 1047

 Score = 29.5 bits (63), Expect = 9.8
 Identities = 16/51 (31%), Positives = 24/51 (47%), Gaps = 2/51 (3%)
 Frame = -1

Query: 524 ALPRPSEPKPTSPARGAPCRSTNEALAETW--SQKNQKLSPQVRSTATLPV 378
           A  R  +P P S     P R   EA  +TW  S + +KL P++   +  P+
Sbjct: 412 AFQRACQPLPASQPCSEPVRPAQEAEEKTWLPSCRKEKLQPRLSEHSGPPI 462


>AF495726-1|AAQ06680.1|  892|Homo sapiens unknown protein.
          Length = 892

 Score = 29.5 bits (63), Expect = 9.8
 Identities = 16/51 (31%), Positives = 24/51 (47%), Gaps = 2/51 (3%)
 Frame = -1

Query: 524 ALPRPSEPKPTSPARGAPCRSTNEALAETW--SQKNQKLSPQVRSTATLPV 378
           A  R  +P P S     P R   EA  +TW  S + +KL P++   +  P+
Sbjct: 257 AFQRACQPLPASQPCSEPVRPAQEAEEKTWLPSCRKEKLQPRLSEHSGPPI 307


>AF356193-1|AAK32718.1| 1037|Homo sapiens caspase recruitment domain
            protein 6 protein.
          Length = 1037

 Score = 29.5 bits (63), Expect = 9.8
 Identities = 16/46 (34%), Positives = 26/46 (56%), Gaps = 3/46 (6%)
 Frame = -1

Query: 509  SEPKPTSPARGAPCRSTNEALAETW---SQKNQKLSPQVRSTATLP 381
            S+P  T P+   PC+ST    ++ W   S+ +Q   PQ +S++T P
Sbjct: 977  SQPSQTKPS---PCKSTQPKPSQPWPPQSKPSQPRPPQPKSSSTNP 1019


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 68,345,780
Number of Sequences: 237096
Number of extensions: 1269674
Number of successful extensions: 4263
Number of sequences better than 10.0: 17
Number of HSP's better than 10.0 without gapping: 3859
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4217
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 6522878360
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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