Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P12_pT_C22
(812 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
J05262-1|AAA52423.1| 353|Homo sapiens FDPS protein. 182 2e-45
M29863-1|AAA35820.1| 346|Homo sapiens protein ( Human farnesyl ... 181 3e-45
D14697-1|BAA03523.2| 420|Homo sapiens KIAA1293 protein. 181 3e-45
BC010004-1|AAH10004.1| 419|Homo sapiens farnesyl diphosphate sy... 181 3e-45
AL139410-1|CAI12715.1| 419|Homo sapiens farnesyl diphosphate sy... 181 3e-45
Z47055-1|CAA87327.1| 348|Homo sapiens farnesyl pyrophosphate sy... 165 2e-40
BC050292-1|AAH50292.1| 298|Homo sapiens LOC619190 protein protein. 149 1e-35
M87434-1|AAA60607.1| 727|Homo sapiens 71 kDa 2'5' oligoadenylat... 30 8.7
M87284-1|AAA60606.1| 687|Homo sapiens 2'5' oligoadenylate synth... 30 8.7
BC049215-1|AAH49215.1| 687|Homo sapiens 2'-5'-oligoadenylate sy... 30 8.7
>J05262-1|AAA52423.1| 353|Homo sapiens FDPS protein.
Length = 353
Score = 182 bits (442), Expect = 2e-45
Identities = 95/250 (38%), Positives = 136/250 (54%), Gaps = 1/250 (0%)
Frame = -3
Query: 807 DIMDGSSVRRGMPCWYRRPEVGITCAFXDSLLIHSSLFEFXKTNFRTNPNYMKMFELFNE 628
DIMD S RRG CWY++P VG+ A D+ L+ + ++ K R P Y+ + ELF +
Sbjct: 104 DIMDSSLTRRGQTCWYQKPGVGLD-AINDANLLEACIYRLLKLYCREQPYYLNLIELFLQ 162
Query: 627 TLWRTSMGQHLDHVTGNR-KTDYSSFTLDRXXXXXXXXXXXXXYNLPVSLGLLLAENVDE 451
+ ++T +GQ LD +T + D FT R + LP++ + +A E
Sbjct: 163 SSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGE 222
Query: 450 KIYKSAQDICLEIGTMFQIQDDFIDCFGDEIKTGKVGTDIQERKCTWLAVQALQRCTEAQ 271
K + +A+ I LE+G FQIQDD++D FGD TGK+GTDIQ+ KC+WL VQ LQR T Q
Sbjct: 223 KEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQ 282
Query: 270 RTVFKACYGSSEPAHVERIKRLYEDLHLPQIYKHQEKAMYDNIIRQIENIPIEAARVLFK 91
+ K YG E V R+K LYE+L LP ++ E+ Y +I+ IE +F
Sbjct: 283 YQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFL 342
Query: 90 KLLDITYNRQ 61
L Y R+
Sbjct: 343 GLARKIYKRR 352
>M29863-1|AAA35820.1| 346|Homo sapiens protein ( Human farnesyl
pyrophosphate synthetase mRNA (hpt807), 3' end. ).
Length = 346
Score = 181 bits (440), Expect = 3e-45
Identities = 95/250 (38%), Positives = 136/250 (54%), Gaps = 1/250 (0%)
Frame = -3
Query: 807 DIMDGSSVRRGMPCWYRRPEVGITCAFXDSLLIHSSLFEFXKTNFRTNPNYMKMFELFNE 628
DIMD S RRG CWY++P VG+ A D+ L+ + ++ K R P Y+ + ELF +
Sbjct: 97 DIMDSSLTRRGQICWYQKPGVGLD-AINDANLLEACIYRLLKLYCREQPYYLNLIELFLQ 155
Query: 627 TLWRTSMGQHLDHVTGNR-KTDYSSFTLDRXXXXXXXXXXXXXYNLPVSLGLLLAENVDE 451
+ ++T +GQ LD +T + D FT R + LP++ + +A E
Sbjct: 156 SSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGE 215
Query: 450 KIYKSAQDICLEIGTMFQIQDDFIDCFGDEIKTGKVGTDIQERKCTWLAVQALQRCTEAQ 271
K + +A+ I LE+G FQIQDD++D FGD TGK+GTDIQ+ KC+WL VQ LQR T Q
Sbjct: 216 KEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQ 275
Query: 270 RTVFKACYGSSEPAHVERIKRLYEDLHLPQIYKHQEKAMYDNIIRQIENIPIEAARVLFK 91
+ K YG E V R+K LYE+L LP ++ E+ Y +I+ IE +F
Sbjct: 276 YQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFL 335
Query: 90 KLLDITYNRQ 61
L Y R+
Sbjct: 336 GLARKIYKRR 345
>D14697-1|BAA03523.2| 420|Homo sapiens KIAA1293 protein.
Length = 420
Score = 181 bits (440), Expect = 3e-45
Identities = 95/250 (38%), Positives = 136/250 (54%), Gaps = 1/250 (0%)
Frame = -3
Query: 807 DIMDGSSVRRGMPCWYRRPEVGITCAFXDSLLIHSSLFEFXKTNFRTNPNYMKMFELFNE 628
DIMD S RRG CWY++P VG+ A D+ L+ + ++ K R P Y+ + ELF +
Sbjct: 171 DIMDSSLTRRGQICWYQKPGVGLD-AINDANLLEACIYRLLKLYCREQPYYLNLIELFLQ 229
Query: 627 TLWRTSMGQHLDHVTGNR-KTDYSSFTLDRXXXXXXXXXXXXXYNLPVSLGLLLAENVDE 451
+ ++T +GQ LD +T + D FT R + LP++ + +A E
Sbjct: 230 SSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGE 289
Query: 450 KIYKSAQDICLEIGTMFQIQDDFIDCFGDEIKTGKVGTDIQERKCTWLAVQALQRCTEAQ 271
K + +A+ I LE+G FQIQDD++D FGD TGK+GTDIQ+ KC+WL VQ LQR T Q
Sbjct: 290 KEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQ 349
Query: 270 RTVFKACYGSSEPAHVERIKRLYEDLHLPQIYKHQEKAMYDNIIRQIENIPIEAARVLFK 91
+ K YG E V R+K LYE+L LP ++ E+ Y +I+ IE +F
Sbjct: 350 YQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFL 409
Query: 90 KLLDITYNRQ 61
L Y R+
Sbjct: 410 GLARKIYKRR 419
>BC010004-1|AAH10004.1| 419|Homo sapiens farnesyl diphosphate
synthase (farnesyl pyrophosphate synthetase,
dimethylallyl protein.
Length = 419
Score = 181 bits (440), Expect = 3e-45
Identities = 95/250 (38%), Positives = 136/250 (54%), Gaps = 1/250 (0%)
Frame = -3
Query: 807 DIMDGSSVRRGMPCWYRRPEVGITCAFXDSLLIHSSLFEFXKTNFRTNPNYMKMFELFNE 628
DIMD S RRG CWY++P VG+ A D+ L+ + ++ K R P Y+ + ELF +
Sbjct: 170 DIMDSSLTRRGQICWYQKPGVGLD-AINDANLLEACIYRLLKLYCREQPYYLNLIELFLQ 228
Query: 627 TLWRTSMGQHLDHVTGNR-KTDYSSFTLDRXXXXXXXXXXXXXYNLPVSLGLLLAENVDE 451
+ ++T +GQ LD +T + D FT R + LP++ + +A E
Sbjct: 229 SSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGE 288
Query: 450 KIYKSAQDICLEIGTMFQIQDDFIDCFGDEIKTGKVGTDIQERKCTWLAVQALQRCTEAQ 271
K + +A+ I LE+G FQIQDD++D FGD TGK+GTDIQ+ KC+WL VQ LQR T Q
Sbjct: 289 KEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQ 348
Query: 270 RTVFKACYGSSEPAHVERIKRLYEDLHLPQIYKHQEKAMYDNIIRQIENIPIEAARVLFK 91
+ K YG E V R+K LYE+L LP ++ E+ Y +I+ IE +F
Sbjct: 349 YQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFL 408
Query: 90 KLLDITYNRQ 61
L Y R+
Sbjct: 409 GLARKIYKRR 418
>AL139410-1|CAI12715.1| 419|Homo sapiens farnesyl diphosphate
synthase (farnesyl pyrophosphate synthetase,
dimethylallyl protein.
Length = 419
Score = 181 bits (440), Expect = 3e-45
Identities = 95/250 (38%), Positives = 136/250 (54%), Gaps = 1/250 (0%)
Frame = -3
Query: 807 DIMDGSSVRRGMPCWYRRPEVGITCAFXDSLLIHSSLFEFXKTNFRTNPNYMKMFELFNE 628
DIMD S RRG CWY++P VG+ A D+ L+ + ++ K R P Y+ + ELF +
Sbjct: 170 DIMDSSLTRRGQICWYQKPGVGLD-AINDANLLEACIYRLLKLYCREQPYYLNLIELFLQ 228
Query: 627 TLWRTSMGQHLDHVTGNR-KTDYSSFTLDRXXXXXXXXXXXXXYNLPVSLGLLLAENVDE 451
+ ++T +GQ LD +T + D FT R + LP++ + +A E
Sbjct: 229 SSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGE 288
Query: 450 KIYKSAQDICLEIGTMFQIQDDFIDCFGDEIKTGKVGTDIQERKCTWLAVQALQRCTEAQ 271
K + +A+ I LE+G FQIQDD++D FGD TGK+GTDIQ+ KC+WL VQ LQR T Q
Sbjct: 289 KEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQ 348
Query: 270 RTVFKACYGSSEPAHVERIKRLYEDLHLPQIYKHQEKAMYDNIIRQIENIPIEAARVLFK 91
+ K YG E V R+K LYE+L LP ++ E+ Y +I+ IE +F
Sbjct: 349 YQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFL 408
Query: 90 KLLDITYNRQ 61
L Y R+
Sbjct: 409 GLARKIYKRR 418
>Z47055-1|CAA87327.1| 348|Homo sapiens farnesyl pyrophosphate
synthetase like-4 protein.
Length = 348
Score = 165 bits (401), Expect = 2e-40
Identities = 91/249 (36%), Positives = 127/249 (51%), Gaps = 1/249 (0%)
Frame = -3
Query: 807 DIMDGSSVRRGMPCWYRRPEVGITCAFXDSLLIHSSLFEFXKTNFRTNPNYMKMFELFNE 628
DIMD S RRG CWY++P VG+ A D+ L+ + ++ K R P Y+ + ELF +
Sbjct: 99 DIMDSSLTRRGQICWYQKPGVGLD-AIDDANLLEACIYPLLKLYCREQPYYLNLIELFLQ 157
Query: 627 TLWRTSMGQHLDHVTGNR-KTDYSSFTLDRXXXXXXXXXXXXXYNLPVSLGLLLAENVDE 451
+ ++T +GQ LD +T + D FT R LP++ V E
Sbjct: 158 SSYQTEIGQTLDLLTXPQGNVDLVRFTEKRYISIVKYKTALSSSYLPIAAAXXXXGIVXE 217
Query: 450 KIYKSAQDICLEIGTMFQIQDDFIDCFGDEIKTGKVGTDIQERKCTWLAVQALQRCTEAQ 271
K + +A I LE+G QIQDD+++ FGD TGK+GTDIQ+ KC L VQ L R T Q
Sbjct: 218 KEHANAXKILLEMGEFSQIQDDYLELFGDPSVTGKIGTDIQDXKCNCLXVQCLXRATPEQ 277
Query: 270 RTVFKACYGSSEPAHVERIKRLYEDLHLPQIYKHQEKAMYDNIIRQIENIPIEAARVLFK 91
+ K YG E V R+K LYE+L LP ++ E+ Y +I+ IE +F
Sbjct: 278 YQILKENYGQKEAEKVPRVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFL 337
Query: 90 KLLDITYNR 64
L Y R
Sbjct: 338 GLARQIYKR 346
>BC050292-1|AAH50292.1| 298|Homo sapiens LOC619190 protein protein.
Length = 298
Score = 149 bits (361), Expect = 1e-35
Identities = 80/228 (35%), Positives = 121/228 (53%), Gaps = 1/228 (0%)
Frame = -3
Query: 807 DIMDGSSVRRGMPCWYRRPEVGITCAFXDSLLIHSSLFEFXKTNFRTNPNYMKMFELFNE 628
DIMD S +G WY++ +G+ A D++L+ + ++ K R P Y+ + ELF +
Sbjct: 72 DIMDSSLTCQGQISWYQKLGMGLD-AINDAILLEACIYCLLKLYCREQPYYLNLMELFQQ 130
Query: 627 TLWRTSMGQHLDHVTGNR-KTDYSSFTLDRXXXXXXXXXXXXXYNLPVSLGLLLAENVDE 451
++T +GQ LD +T + D T R + LPV+ + ++ D+
Sbjct: 131 NSYQTEIGQTLDLITTPQGNVDLRRCTEKRHKSVVKYKTAFYSFYLPVAAAMYMSRMDDK 190
Query: 450 KIYKSAQDICLEIGTMFQIQDDFIDCFGDEIKTGKVGTDIQERKCTWLAVQALQRCTEAQ 271
K + SA+ I LEI FQIQDD++D GD TG+VG D Q+ KC+WL VQ L + T Q
Sbjct: 191 KEHTSAKKILLEIQEFFQIQDDYLDFSGDPSVTGRVGNDFQDNKCSWLVVQCLLQATPEQ 250
Query: 270 RTVFKACYGSSEPAHVERIKRLYEDLHLPQIYKHQEKAMYDNIIRQIE 127
+ K Y E V R+K LYE+L LP ++ EK Y +++ IE
Sbjct: 251 YQILKENYRQKEAEKVARVKALYEELDLPAVFLQYEKDSYSHVMGLIE 298
>M87434-1|AAA60607.1| 727|Homo sapiens 71 kDa 2'5' oligoadenylate
synthetase protein.
Length = 727
Score = 30.3 bits (65), Expect = 8.7
Identities = 12/31 (38%), Positives = 20/31 (64%)
Frame = -1
Query: 344 LVQIYKSANVLGWQFKRCSAVLKHNVQYSKP 252
L+ +YKS+++ G +F C VL+ N S+P
Sbjct: 506 LIDLYKSSDLPGGEFSTCFTVLQRNFIRSRP 536
>M87284-1|AAA60606.1| 687|Homo sapiens 2'5' oligoadenylate
synthetase protein.
Length = 687
Score = 30.3 bits (65), Expect = 8.7
Identities = 12/31 (38%), Positives = 20/31 (64%)
Frame = -1
Query: 344 LVQIYKSANVLGWQFKRCSAVLKHNVQYSKP 252
L+ +YKS+++ G +F C VL+ N S+P
Sbjct: 506 LIDLYKSSDLPGGEFSTCFTVLQRNFIRSRP 536
>BC049215-1|AAH49215.1| 687|Homo sapiens 2'-5'-oligoadenylate
synthetase 2, 69/71kDa protein.
Length = 687
Score = 30.3 bits (65), Expect = 8.7
Identities = 12/31 (38%), Positives = 20/31 (64%)
Frame = -1
Query: 344 LVQIYKSANVLGWQFKRCSAVLKHNVQYSKP 252
L+ +YKS+++ G +F C VL+ N S+P
Sbjct: 506 LIDLYKSSDLPGGEFSTCFTVLQRNFIRSRP 536
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 116,024,159
Number of Sequences: 237096
Number of extensions: 2302611
Number of successful extensions: 4267
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4153
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4253
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 10092110758
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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