Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P12_pT_B15
(675 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
J04794-1|AAA51711.1| 325|Homo sapiens ALDR1 protein. 169 1e-41
CR457010-1|CAG33291.1| 325|Homo sapiens AKR1A1 protein. 169 1e-41
BT007003-1|AAP35649.1| 325|Homo sapiens aldo-keto reductase fam... 169 1e-41
BC005394-1|AAH05394.1| 325|Homo sapiens aldo-keto reductase fam... 169 1e-41
BC000670-1|AAH00670.1| 325|Homo sapiens aldo-keto reductase fam... 169 1e-41
AL355480-3|CAI22459.1| 325|Homo sapiens aldo-keto reductase fam... 169 1e-41
AF112485-1|AAF01260.1| 325|Homo sapiens aldehyde reductase prot... 169 1e-41
AF036683-1|AAB92369.1| 325|Homo sapiens aldehyde reductase prot... 169 1e-41
U05861-1|AAA18115.1| 323|Homo sapiens hepatic dihydrodiol dehyd... 167 2e-41
U05684-1|AAA16227.1| 323|Homo sapiens dihydrodiol dehydrogenase... 167 2e-41
U05598-1|AAA20937.1| 323|Homo sapiens dihydrodiol dehydrogenase... 167 2e-41
S68330-1|AAD14013.1| 323|Homo sapiens chlordecone reductase hom... 167 2e-41
M86609-1|AAB02880.1| 323|Homo sapiens dihydrodiol dehydrogenase... 167 2e-41
D26124-1|BAA05121.1| 306|Homo sapiens dihydrodiol dehydrogenase... 167 2e-41
BT007197-1|AAP35861.1| 323|Homo sapiens aldo-keto reductase fam... 167 2e-41
BT006653-1|AAP35299.1| 323|Homo sapiens aldo-keto reductase fam... 167 2e-41
BC063574-1|AAH63574.1| 323|Homo sapiens aldo-keto reductase fam... 167 2e-41
BC040210-1|AAH40210.1| 323|Homo sapiens aldo-keto reductase fam... 167 2e-41
BC020216-1|AAH20216.1| 323|Homo sapiens aldo-keto reductase fam... 167 2e-41
BC015490-1|AAH15490.1| 323|Homo sapiens aldo-keto reductase fam... 167 2e-41
BC007024-1|AAH07024.1| 323|Homo sapiens aldo-keto reductase fam... 167 2e-41
AL713867-2|CAI16409.1| 323|Homo sapiens aldo-keto reductase fam... 167 2e-41
AL713867-1|CAI16408.1| 323|Homo sapiens aldo-keto reductase fam... 167 2e-41
AL391427-1|CAI14726.1| 323|Homo sapiens aldo-keto reductase fam... 167 2e-41
AB032153-1|BAA92891.1| 323|Homo sapiens bile acid-binding prote... 167 2e-41
AB032150-1|BAA92886.1| 323|Homo sapiens 20 alph-hydroxysteroid ... 167 2e-41
AB031084-1|BAA92884.1| 323|Homo sapiens bile acid-binding prote... 167 2e-41
AB031083-1|BAA92883.1| 323|Homo sapiens 20 alpha-hydroxysteroid... 167 2e-41
AB021654-1|BAA36169.1| 323|Homo sapiens DD2/bile acid-binding p... 167 2e-41
L32592-1|AAB38486.1| 323|Homo sapiens dihydrodiol dehydrogenase... 166 7e-41
S68287-1|AAD14010.1| 323|Homo sapiens chlordecone reductase pro... 163 5e-40
M33375-1|AAA35658.1| 308|Homo sapiens protein ( Human chlordeco... 163 5e-40
D26125-1|BAA05122.1| 321|Homo sapiens 3 alpha-hydroxysteroid/di... 163 5e-40
AB045829-1|BAA99542.1| 323|Homo sapiens 3alpha-hydroxysteroid d... 163 5e-40
AB032163-1|BAA92893.1| 323|Homo sapiens dihydrodiol dehydrogena... 163 5e-40
AB031085-1|BAA92885.1| 323|Homo sapiens dihydrodiol dehydrogena... 163 5e-40
S68290-1|AAD14012.1| 320|Homo sapiens chlordecone reductase hom... 163 7e-40
AL355303-2|CAI14202.1| 323|Homo sapiens aldo-keto reductase fam... 163 7e-40
BC020744-1|AAH20744.1| 323|Homo sapiens aldo-keto reductase fam... 162 9e-40
Z28339-1|CAA82193.1| 326|Homo sapiens delta 4-3-oxosteroid 5 be... 162 1e-39
BC130627-1|AAI30628.1| 326|Homo sapiens aldo-keto reductase fam... 162 1e-39
BC130625-1|AAI30626.1| 326|Homo sapiens aldo-keto reductase fam... 162 1e-39
AF283659-1|AAG39381.1| 326|Homo sapiens 5-beta steroid reductas... 162 1e-39
CR542203-1|CAG47000.1| 316|Homo sapiens AKR1B1 protein. 161 3e-39
DQ269985-1|ABB76132.1| 323|Homo sapiens type II 3a-hydroxystero... 159 6e-39
D17793-1|BAA04619.2| 325|Homo sapiens KIAA0119 protein. 159 8e-39
BT007286-1|AAP35950.1| 323|Homo sapiens aldo-keto reductase fam... 159 8e-39
BC019230-1|AAH19230.1| 323|Homo sapiens aldo-keto reductase fam... 159 8e-39
BC001479-1|AAH01479.1| 323|Homo sapiens aldo-keto reductase fam... 159 8e-39
AL391427-4|CAI14729.1| 323|Homo sapiens aldo-keto reductase fam... 159 8e-39
AF149416-1|AAF07272.2| 323|Homo sapiens 3-alpha hydroxysteroid ... 159 8e-39
AB032157-1|BAA92892.1| 323|Homo sapiens prostaglandin F synthas... 159 8e-39
AB018580-1|BAA88488.1| 323|Homo sapiens hluPGFS protein. 159 8e-39
X15414-1|CAA33460.1| 316|Homo sapiens protein ( Human mRNA for ... 159 1e-38
M59783-1|AAA51712.1| 316|Homo sapiens aldose reductase protein. 159 1e-38
M34720-1|AAA35560.1| 316|Homo sapiens protein ( Human aldose re... 159 1e-38
J05474-1|AAA51715.1| 316|Homo sapiens aldose reductase protein. 159 1e-38
J05017-1|AAA51714.1| 316|Homo sapiens ALDR1 protein. 159 1e-38
J04795-1|AAA51713.1| 316|Homo sapiens ALDR1 protein. 159 1e-38
CR450351-1|CAG29347.1| 316|Homo sapiens AKR1B1 protein. 159 1e-38
BT019859-1|AAV38662.1| 316|Homo sapiens aldo-keto reductase fam... 159 1e-38
BC010391-1|AAH10391.1| 316|Homo sapiens aldo-keto reductase fam... 159 1e-38
BC000260-1|AAH00260.1| 316|Homo sapiens aldo-keto reductase fam... 159 1e-38
AF328729-1|AAN09721.1| 316|Homo sapiens CTCL tumor antigen HD-C... 159 1e-38
AF032455-1|AAB88851.1| 316|Homo sapiens aldose reductase protein. 159 1e-38
S68288-1|AAD14011.1| 323|Homo sapiens chlordecone reductase hom... 158 1e-38
L43839-1|AAB41916.1| 323|Homo sapiens 3-alpha-hydroxysteroid de... 158 1e-38
U37100-1|AAC17469.1| 316|Homo sapiens aldose reductase-like pep... 153 5e-37
CR541801-1|CAG46600.1| 316|Homo sapiens AKR1B10 protein. 153 5e-37
BT006794-1|AAP35440.1| 316|Homo sapiens aldo-keto reductase fam... 153 5e-37
BC008837-1|AAH08837.1| 316|Homo sapiens aldo-keto reductase fam... 153 5e-37
BC005387-1|AAH05387.1| 316|Homo sapiens aldo-keto reductase fam... 153 5e-37
AF052577-1|AAC36465.1| 316|Homo sapiens aldo-keto reductase pro... 153 5e-37
AF524864-1|AAO13380.1| 316|Homo sapiens aldo-ketoreductase prot... 150 5e-36
AL713867-3|CAI16410.1| 247|Homo sapiens aldo-keto reductase fam... 140 3e-33
AF263242-1|AAK58523.1| 320|Homo sapiens aldo-keto reductase loo... 116 3e-33
BC002862-1|AAH02862.1| 307|Homo sapiens AKR1CL2 protein protein. 116 3e-33
AB055603-1|BAC54568.1| 307|Homo sapiens aldo-keto reductase rel... 116 3e-33
AB209796-1|BAD93033.1| 260|Homo sapiens aldo-keto reductase fam... 116 6e-26
AB209017-1|BAD92254.1| 286|Homo sapiens aldo-keto reductase fam... 109 7e-24
AL391427-2|CAI14727.1| 302|Homo sapiens aldo-keto reductase fam... 101 3e-21
AL355303-1|CAI14201.1| 302|Homo sapiens aldo-keto reductase fam... 101 3e-21
AB040821-1|BAC54566.1| 263|Homo sapiens aldo-keto reductase rel... 52 3e-14
AB040820-1|BAC54565.1| 250|Homo sapiens aldo-keto reductase rel... 52 3e-14
AF044961-1|AAC15671.1| 85|Homo sapiens aldose reductase-relate... 66 1e-10
AK058142-1|BAB71682.1| 146|Homo sapiens protein ( Homo sapiens ... 65 2e-10
AL355480-2|CAI22458.1| 147|Homo sapiens aldo-keto reductase fam... 54 6e-07
AB028065-1|BAA88489.1| 67|Homo sapiens prostaglandin F synthas... 46 9e-05
AB040822-1|BAC54567.1| 222|Homo sapiens aldo-keto reductase rel... 46 1e-04
BC101205-1|AAI01206.1| 129|Homo sapiens aldo-keto reductase fam... 45 3e-04
BC101204-1|AAI01205.1| 129|Homo sapiens aldo-keto reductase fam... 45 3e-04
AK131335-1|BAD18494.1| 129|Homo sapiens protein ( Homo sapiens ... 45 3e-04
AB037902-1|BAA92887.1| 130|Homo sapiens truncated aldo-keto red... 42 0.002
AB037905-2|BAA92890.1| 45|Homo sapiens truncated aldo-keto red... 40 0.008
Y16675-1|CAA76347.1| 330|Homo sapiens aflatoxin B1-aldehyde red... 39 0.019
BT007347-1|AAP36011.1| 330|Homo sapiens aldo-keto reductase fam... 39 0.019
BC013996-1|AAH13996.1| 330|Homo sapiens AKR7A2 protein protein. 39 0.019
BC012171-1|AAH12171.1| 330|Homo sapiens AKR7A2 protein protein. 39 0.019
BC011586-1|AAH11586.1| 330|Homo sapiens AKR7A2 protein protein. 39 0.019
BC010852-1|AAH10852.1| 330|Homo sapiens AKR7A2 protein protein. 39 0.019
BC007352-1|AAH07352.2| 358|Homo sapiens AKR7A2 protein protein. 39 0.019
BC004111-1|AAH04111.3| 330|Homo sapiens AKR7A2 protein protein. 39 0.019
AL035413-8|CAB72321.1| 330|Homo sapiens aldo-keto reductase fam... 39 0.019
AF026947-1|AAC52104.1| 330|Homo sapiens aflatoxin aldehyde redu... 39 0.019
AJ278012-1|CAC79668.1| 259|Homo sapiens aflatoxin B1 aldehyde r... 38 0.033
BC042420-1|AAH42420.2| 331|Homo sapiens aldo-keto reductase fam... 36 0.13
BC031562-1|AAH31562.1| 331|Homo sapiens aldo-keto reductase fam... 36 0.13
AJ271799-1|CAC81076.1| 331|Homo sapiens aflatoxin B1 aldehyde r... 36 0.13
AF040639-1|AAD02195.1| 331|Homo sapiens aflatoxin B1-aldehyde r... 36 0.13
AK025747-1|BAB15231.1| 171|Homo sapiens protein ( Homo sapiens ... 36 0.17
AK001267-1|BAA91590.1| 639|Homo sapiens protein ( Homo sapiens ... 36 0.17
AC093727-1|AAX81992.1| 639|Homo sapiens unknown protein. 36 0.17
BC025709-1|AAH25709.1| 331|Homo sapiens aldo-keto reductase fam... 35 0.23
AL035413-11|CAI22232.1| 331|Homo sapiens aldo-keto reductase fa... 35 0.23
AK131086-1|BAC85136.1| 217|Homo sapiens FLJ00288 protein protein. 33 0.70
L35546-1|AAA65028.1| 274|Homo sapiens gamma-glutamylcysteine sy... 30 6.5
CR541833-1|CAG46632.1| 274|Homo sapiens GCLM protein. 30 6.5
BC041809-1|AAH41809.1| 274|Homo sapiens glutamate-cysteine liga... 30 6.5
AY773965-1|AAV28733.1| 274|Homo sapiens glutamate-cysteine liga... 30 6.5
AL117351-10|CAI22976.1| 274|Homo sapiens glutamate-cysteine lig... 30 6.5
AL049796-2|CAI21813.1| 274|Homo sapiens glutamate-cysteine liga... 30 6.5
>J04794-1|AAA51711.1| 325|Homo sapiens ALDR1 protein.
Length = 325
Score = 169 bits (410), Expect = 1e-41
Identities = 90/220 (40%), Positives = 129/220 (58%), Gaps = 11/220 (5%)
Frame = -2
Query: 674 KLWNDKHARXQVVPALQESLKKLGLXYIDLYLIHFPIATKPDDSP-----------DNID 528
KLWN KH V PAL+++L L L Y+DLYL+H+P A + D+P D+
Sbjct: 80 KLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNADGTICYDSTH 139
Query: 527 YLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEPLVAH 348
Y ETW+ ++ GL +++G+SNFN+ QI ++S + +RP + Q+E +P Q L+AH
Sbjct: 140 YKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAH 199
Query: 347 CQSLGIAVMAYSPFGFVVSRGQTGAPPPRSDDPTLTALANKYRKSVGQILLRYLIDRGLI 168
CQ+ G+ V AYSP G + P ++P + ALA KY +S QILLR+ + R +I
Sbjct: 200 CQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEKYGRSPAQILLRWQVQRKVI 259
Query: 167 PIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKKHRGI 48
IPKS RI QNI +FDF + EE+ +N NK R I
Sbjct: 260 CIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWRYI 299
>CR457010-1|CAG33291.1| 325|Homo sapiens AKR1A1 protein.
Length = 325
Score = 169 bits (410), Expect = 1e-41
Identities = 90/220 (40%), Positives = 129/220 (58%), Gaps = 11/220 (5%)
Frame = -2
Query: 674 KLWNDKHARXQVVPALQESLKKLGLXYIDLYLIHFPIATKPDDSP-----------DNID 528
KLWN KH V PAL+++L L L Y+DLYL+H+P A + D+P D+
Sbjct: 80 KLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNADGTICYDSTH 139
Query: 527 YLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEPLVAH 348
Y ETW+ ++ GL +++G+SNFN+ QI ++S + +RP + Q+E +P Q L+AH
Sbjct: 140 YKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAH 199
Query: 347 CQSLGIAVMAYSPFGFVVSRGQTGAPPPRSDDPTLTALANKYRKSVGQILLRYLIDRGLI 168
CQ+ G+ V AYSP G + P ++P + ALA KY +S QILLR+ + R +I
Sbjct: 200 CQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEKYGRSPAQILLRWQVQRKVI 259
Query: 167 PIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKKHRGI 48
IPKS RI QNI +FDF + EE+ +N NK R I
Sbjct: 260 CIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWRYI 299
>BT007003-1|AAP35649.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 169 bits (410), Expect = 1e-41
Identities = 90/220 (40%), Positives = 129/220 (58%), Gaps = 11/220 (5%)
Frame = -2
Query: 674 KLWNDKHARXQVVPALQESLKKLGLXYIDLYLIHFPIATKPDDSP-----------DNID 528
KLWN KH V PAL+++L L L Y+DLYL+H+P A + D+P D+
Sbjct: 80 KLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNADGTICYDSTH 139
Query: 527 YLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEPLVAH 348
Y ETW+ ++ GL +++G+SNFN+ QI ++S + +RP + Q+E +P Q L+AH
Sbjct: 140 YKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAH 199
Query: 347 CQSLGIAVMAYSPFGFVVSRGQTGAPPPRSDDPTLTALANKYRKSVGQILLRYLIDRGLI 168
CQ+ G+ V AYSP G + P ++P + ALA KY +S QILLR+ + R +I
Sbjct: 200 CQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEKYGRSPAQILLRWQVQRKVI 259
Query: 167 PIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKKHRGI 48
IPKS RI QNI +FDF + EE+ +N NK R I
Sbjct: 260 CIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWRYI 299
>BC005394-1|AAH05394.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 169 bits (410), Expect = 1e-41
Identities = 90/220 (40%), Positives = 129/220 (58%), Gaps = 11/220 (5%)
Frame = -2
Query: 674 KLWNDKHARXQVVPALQESLKKLGLXYIDLYLIHFPIATKPDDSP-----------DNID 528
KLWN KH V PAL+++L L L Y+DLYL+H+P A + D+P D+
Sbjct: 80 KLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNADGTICYDSTH 139
Query: 527 YLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEPLVAH 348
Y ETW+ ++ GL +++G+SNFN+ QI ++S + +RP + Q+E +P Q L+AH
Sbjct: 140 YKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAH 199
Query: 347 CQSLGIAVMAYSPFGFVVSRGQTGAPPPRSDDPTLTALANKYRKSVGQILLRYLIDRGLI 168
CQ+ G+ V AYSP G + P ++P + ALA KY +S QILLR+ + R +I
Sbjct: 200 CQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEKYGRSPAQILLRWQVQRKVI 259
Query: 167 PIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKKHRGI 48
IPKS RI QNI +FDF + EE+ +N NK R I
Sbjct: 260 CIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWRYI 299
>BC000670-1|AAH00670.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 169 bits (410), Expect = 1e-41
Identities = 90/220 (40%), Positives = 129/220 (58%), Gaps = 11/220 (5%)
Frame = -2
Query: 674 KLWNDKHARXQVVPALQESLKKLGLXYIDLYLIHFPIATKPDDSP-----------DNID 528
KLWN KH V PAL+++L L L Y+DLYL+H+P A + D+P D+
Sbjct: 80 KLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNADGTICYDSTH 139
Query: 527 YLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEPLVAH 348
Y ETW+ ++ GL +++G+SNFN+ QI ++S + +RP + Q+E +P Q L+AH
Sbjct: 140 YKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAH 199
Query: 347 CQSLGIAVMAYSPFGFVVSRGQTGAPPPRSDDPTLTALANKYRKSVGQILLRYLIDRGLI 168
CQ+ G+ V AYSP G + P ++P + ALA KY +S QILLR+ + R +I
Sbjct: 200 CQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEKYGRSPAQILLRWQVQRKVI 259
Query: 167 PIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKKHRGI 48
IPKS RI QNI +FDF + EE+ +N NK R I
Sbjct: 260 CIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWRYI 299
>AL355480-3|CAI22459.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehydetase, 1 protein.
Length = 325
Score = 169 bits (410), Expect = 1e-41
Identities = 90/220 (40%), Positives = 129/220 (58%), Gaps = 11/220 (5%)
Frame = -2
Query: 674 KLWNDKHARXQVVPALQESLKKLGLXYIDLYLIHFPIATKPDDSP-----------DNID 528
KLWN KH V PAL+++L L L Y+DLYL+H+P A + D+P D+
Sbjct: 80 KLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNADGTICYDSTH 139
Query: 527 YLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEPLVAH 348
Y ETW+ ++ GL +++G+SNFN+ QI ++S + +RP + Q+E +P Q L+AH
Sbjct: 140 YKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAH 199
Query: 347 CQSLGIAVMAYSPFGFVVSRGQTGAPPPRSDDPTLTALANKYRKSVGQILLRYLIDRGLI 168
CQ+ G+ V AYSP G + P ++P + ALA KY +S QILLR+ + R +I
Sbjct: 200 CQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEKYGRSPAQILLRWQVQRKVI 259
Query: 167 PIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKKHRGI 48
IPKS RI QNI +FDF + EE+ +N NK R I
Sbjct: 260 CIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWRYI 299
>AF112485-1|AAF01260.1| 325|Homo sapiens aldehyde reductase
protein.
Length = 325
Score = 169 bits (410), Expect = 1e-41
Identities = 90/220 (40%), Positives = 129/220 (58%), Gaps = 11/220 (5%)
Frame = -2
Query: 674 KLWNDKHARXQVVPALQESLKKLGLXYIDLYLIHFPIATKPDDSP-----------DNID 528
KLWN KH V PAL+++L L L Y+DLYL+H+P A + D+P D+
Sbjct: 80 KLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNADGTICYDSTH 139
Query: 527 YLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEPLVAH 348
Y ETW+ ++ GL +++G+SNFN+ QI ++S + +RP + Q+E +P Q L+AH
Sbjct: 140 YKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAH 199
Query: 347 CQSLGIAVMAYSPFGFVVSRGQTGAPPPRSDDPTLTALANKYRKSVGQILLRYLIDRGLI 168
CQ+ G+ V AYSP G + P ++P + ALA KY +S QILLR+ + R +I
Sbjct: 200 CQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEKYGRSPAQILLRWQVQRKVI 259
Query: 167 PIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKKHRGI 48
IPKS RI QNI +FDF + EE+ +N NK R I
Sbjct: 260 CIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWRYI 299
>AF036683-1|AAB92369.1| 325|Homo sapiens aldehyde reductase
protein.
Length = 325
Score = 169 bits (410), Expect = 1e-41
Identities = 90/220 (40%), Positives = 129/220 (58%), Gaps = 11/220 (5%)
Frame = -2
Query: 674 KLWNDKHARXQVVPALQESLKKLGLXYIDLYLIHFPIATKPDDSP-----------DNID 528
KLWN KH V PAL+++L L L Y+DLYL+H+P A + D+P D+
Sbjct: 80 KLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNADGTICYDSTH 139
Query: 527 YLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEPLVAH 348
Y ETW+ ++ GL +++G+SNFN+ QI ++S + +RP + Q+E +P Q L+AH
Sbjct: 140 YKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAH 199
Query: 347 CQSLGIAVMAYSPFGFVVSRGQTGAPPPRSDDPTLTALANKYRKSVGQILLRYLIDRGLI 168
CQ+ G+ V AYSP G + P ++P + ALA KY +S QILLR+ + R +I
Sbjct: 200 CQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEKYGRSPAQILLRWQVQRKVI 259
Query: 167 PIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKKHRGI 48
IPKS RI QNI +FDF + EE+ +N NK R I
Sbjct: 260 CIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWRYI 299
>U05861-1|AAA18115.1| 323|Homo sapiens hepatic dihydrodiol
dehydrogenase protein.
Length = 323
Score = 167 bits (407), Expect = 2e-41
Identities = 91/235 (38%), Positives = 134/235 (57%), Gaps = 14/235 (5%)
Frame = -2
Query: 674 KLWNDKHARXQVVPALQESLKKLGLXYIDLYLIHFPIATKPDDSP-----------DNID 528
KLW + H V PAL+ SLK L L Y+DLYLIHFP++ KP + D +D
Sbjct: 84 KLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVD 143
Query: 527 YLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR--PVINQIEVNPTNTQEPLV 354
TW+ ++ + GLA+SIGVSNFN Q+ +++ ++ PV NQ+E +P Q L+
Sbjct: 144 LCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLL 203
Query: 353 AHCQSLGIAVMAYSPFGFVVSRGQTGAPPP-RSDDPTLTALANKYRKSVGQILLRYLIDR 177
C+S I ++AYS G P +DP L ALA K++++ I LRY + R
Sbjct: 204 DFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQR 263
Query: 176 GLIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKKHRGIDISDWKDDPNEP 12
G++ + KS N+QRI QN+ +F+FQLT EE+ AI+ N+ R + + + PN P
Sbjct: 264 GVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYP 318
>U05684-1|AAA16227.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 167 bits (407), Expect = 2e-41
Identities = 91/235 (38%), Positives = 134/235 (57%), Gaps = 14/235 (5%)
Frame = -2
Query: 674 KLWNDKHARXQVVPALQESLKKLGLXYIDLYLIHFPIATKPDDSP-----------DNID 528
KLW + H V PAL+ SLK L L Y+DLYLIHFP++ KP + D +D
Sbjct: 84 KLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVD 143
Query: 527 YLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR--PVINQIEVNPTNTQEPLV 354
TW+ ++ + GLA+SIGVSNFN Q+ +++ ++ PV NQ+E +P Q L+
Sbjct: 144 LCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLL 203
Query: 353 AHCQSLGIAVMAYSPFGFVVSRGQTGAPPP-RSDDPTLTALANKYRKSVGQILLRYLIDR 177
C+S I ++AYS G P +DP L ALA K++++ I LRY + R
Sbjct: 204 DFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQR 263
Query: 176 GLIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKKHRGIDISDWKDDPNEP 12
G++ + KS N+QRI QN+ +F+FQLT EE+ AI+ N+ R + + + PN P
Sbjct: 264 GVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYP 318
>U05598-1|AAA20937.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 167 bits (407), Expect = 2e-41
Identities = 91/235 (38%), Positives = 134/235 (57%), Gaps = 14/235 (5%)
Frame = -2
Query: 674 KLWNDKHARXQVVPALQESLKKLGLXYIDLYLIHFPIATKPDDSP-----------DNID 528
KLW++ H V PAL+ SLK L L Y+DLYLIHFP++ KP + D +D
Sbjct: 84 KLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVD 143
Query: 527 YLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR--PVINQIEVNPTNTQEPLV 354
TW+ M+ + GLA+SIGVSNFN + +++ ++ PV NQ+E +P Q L+
Sbjct: 144 LCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLL 203
Query: 353 AHCQSLGIAVMAYSPFGFVVSRGQTGAPPP-RSDDPTLTALANKYRKSVGQILLRYLIDR 177
C+S I ++AYS G P +DP L ALA K++++ I LRY + R
Sbjct: 204 DFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQR 263
Query: 176 GLIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKKHRGIDISDWKDDPNEP 12
G++ + KS N+QRI QN+ +F+FQLT EE+ AI+ N+ R + + + PN P
Sbjct: 264 GVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYP 318
>S68330-1|AAD14013.1| 323|Homo sapiens chlordecone reductase
homolog protein.
Length = 323
Score = 167 bits (407), Expect = 2e-41
Identities = 91/235 (38%), Positives = 134/235 (57%), Gaps = 14/235 (5%)
Frame = -2
Query: 674 KLWNDKHARXQVVPALQESLKKLGLXYIDLYLIHFPIATKPDDSP-----------DNID 528
KLW++ H V PAL+ SLK L L Y+DLYLIHFP++ KP + D +D
Sbjct: 84 KLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVD 143
Query: 527 YLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR--PVINQIEVNPTNTQEPLV 354
TW+ M+ + GLA+SIGVSNFN + +++ ++ PV NQ+E +P Q L+
Sbjct: 144 LCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNEPGLKYEPVCNQVECHPYFNQRKLL 203
Query: 353 AHCQSLGIAVMAYSPFGFVVSRGQTGAPPP-RSDDPTLTALANKYRKSVGQILLRYLIDR 177
C+S I ++AYS G P +DP L ALA K++++ I LRY + R
Sbjct: 204 DFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQR 263
Query: 176 GLIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKKHRGIDISDWKDDPNEP 12
G++ + KS N+QRI QN+ +F+FQLT EE+ AI+ N+ R + + + PN P
Sbjct: 264 GVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYP 318
>M86609-1|AAB02880.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 167 bits (407), Expect = 2e-41
Identities = 91/235 (38%), Positives = 134/235 (57%), Gaps = 14/235 (5%)
Frame = -2
Query: 674 KLWNDKHARXQVVPALQESLKKLGLXYIDLYLIHFPIATKPDDSP-----------DNID 528
KLW + H V PAL+ SLK L L Y+DLYLIHFP++ KP + D +D
Sbjct: 84 KLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVD 143
Query: 527 YLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR--PVINQIEVNPTNTQEPLV 354
TW+ ++ + GLA+SIGVSNFN Q+ +++ ++ PV NQ+E +P Q L+
Sbjct: 144 LCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLL 203
Query: 353 AHCQSLGIAVMAYSPFGFVVSRGQTGAPPP-RSDDPTLTALANKYRKSVGQILLRYLIDR 177
C+S I ++AYS G P +DP L ALA K++++ I LRY + R
Sbjct: 204 DFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQR 263
Query: 176 GLIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKKHRGIDISDWKDDPNEP 12
G++ + KS N+QRI QN+ +F+FQLT EE+ AI+ N+ R + + + PN P
Sbjct: 264 GVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYP 318
>D26124-1|BAA05121.1| 306|Homo sapiens dihydrodiol dehydrogenase
isoform DD1 protein.
Length = 306
Score = 167 bits (407), Expect = 2e-41
Identities = 91/235 (38%), Positives = 134/235 (57%), Gaps = 14/235 (5%)
Frame = -2
Query: 674 KLWNDKHARXQVVPALQESLKKLGLXYIDLYLIHFPIATKPDDSP-----------DNID 528
KLW + H V PAL+ SLK L L Y+DLYLIHFP++ KP + D +D
Sbjct: 67 KLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVD 126
Query: 527 YLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR--PVINQIEVNPTNTQEPLV 354
TW+ ++ + GLA+SIGVSNFN Q+ +++ ++ PV NQ+E +P Q L+
Sbjct: 127 LCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLL 186
Query: 353 AHCQSLGIAVMAYSPFGFVVSRGQTGAPPP-RSDDPTLTALANKYRKSVGQILLRYLIDR 177
C+S I ++AYS G P +DP L ALA K++++ I LRY + R
Sbjct: 187 DFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQR 246
Query: 176 GLIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKKHRGIDISDWKDDPNEP 12
G++ + KS N+QRI QN+ +F+FQLT EE+ AI+ N+ R + + + PN P
Sbjct: 247 GVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYP 301
>BT007197-1|AAP35861.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 167 bits (407), Expect = 2e-41
Identities = 91/235 (38%), Positives = 134/235 (57%), Gaps = 14/235 (5%)
Frame = -2
Query: 674 KLWNDKHARXQVVPALQESLKKLGLXYIDLYLIHFPIATKPDDSP-----------DNID 528
KLW + H V PAL+ SLK L L Y+DLYLIHFP++ KP + D +D
Sbjct: 84 KLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVD 143
Query: 527 YLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR--PVINQIEVNPTNTQEPLV 354
TW+ ++ + GLA+SIGVSNFN Q+ +++ ++ PV NQ+E +P Q L+
Sbjct: 144 LCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLL 203
Query: 353 AHCQSLGIAVMAYSPFGFVVSRGQTGAPPP-RSDDPTLTALANKYRKSVGQILLRYLIDR 177
C+S I ++AYS G P +DP L ALA K++++ I LRY + R
Sbjct: 204 DFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQR 263
Query: 176 GLIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKKHRGIDISDWKDDPNEP 12
G++ + KS N+QRI QN+ +F+FQLT EE+ AI+ N+ R + + + PN P
Sbjct: 264 GVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYP 318
>BT006653-1|AAP35299.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 167 bits (407), Expect = 2e-41
Identities = 91/235 (38%), Positives = 134/235 (57%), Gaps = 14/235 (5%)
Frame = -2
Query: 674 KLWNDKHARXQVVPALQESLKKLGLXYIDLYLIHFPIATKPDDSP-----------DNID 528
KLW++ H V PAL+ SLK L L Y+DLYLIHFP++ KP + D +D
Sbjct: 84 KLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVD 143
Query: 527 YLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR--PVINQIEVNPTNTQEPLV 354
TW+ M+ + GLA+SIGVSNFN + +++ ++ PV NQ+E +P Q L+
Sbjct: 144 LCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLL 203
Query: 353 AHCQSLGIAVMAYSPFGFVVSRGQTGAPPP-RSDDPTLTALANKYRKSVGQILLRYLIDR 177
C+S I ++AYS G P +DP L ALA K++++ I LRY + R
Sbjct: 204 DFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQR 263
Query: 176 GLIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKKHRGIDISDWKDDPNEP 12
G++ + KS N+QRI QN+ +F+FQLT EE+ AI+ N+ R + + + PN P
Sbjct: 264 GVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYP 318
>BC063574-1|AAH63574.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 167 bits (407), Expect = 2e-41
Identities = 91/235 (38%), Positives = 134/235 (57%), Gaps = 14/235 (5%)
Frame = -2
Query: 674 KLWNDKHARXQVVPALQESLKKLGLXYIDLYLIHFPIATKPDDSP-----------DNID 528
KLW++ H V PAL+ SLK L L Y+DLYLIHFP++ KP + D +D
Sbjct: 84 KLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVD 143
Query: 527 YLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR--PVINQIEVNPTNTQEPLV 354
TW+ M+ + GLA+SIGVSNFN + +++ ++ PV NQ+E +P Q L+
Sbjct: 144 LCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLL 203
Query: 353 AHCQSLGIAVMAYSPFGFVVSRGQTGAPPP-RSDDPTLTALANKYRKSVGQILLRYLIDR 177
C+S I ++AYS G P +DP L ALA K++++ I LRY + R
Sbjct: 204 DFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQR 263
Query: 176 GLIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKKHRGIDISDWKDDPNEP 12
G++ + KS N+QRI QN+ +F+FQLT EE+ AI+ N+ R + + + PN P
Sbjct: 264 GVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYP 318
>BC040210-1|AAH40210.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 167 bits (407), Expect = 2e-41
Identities = 91/235 (38%), Positives = 134/235 (57%), Gaps = 14/235 (5%)
Frame = -2
Query: 674 KLWNDKHARXQVVPALQESLKKLGLXYIDLYLIHFPIATKPDDSP-----------DNID 528
KLW + H V PAL+ SLK L L Y+DLYLIHFP++ KP + D +D
Sbjct: 84 KLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVD 143
Query: 527 YLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR--PVINQIEVNPTNTQEPLV 354
TW+ ++ + GLA+SIGVSNFN Q+ +++ ++ PV NQ+E +P Q L+
Sbjct: 144 LCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLL 203
Query: 353 AHCQSLGIAVMAYSPFGFVVSRGQTGAPPP-RSDDPTLTALANKYRKSVGQILLRYLIDR 177
C+S I ++AYS G P +DP L ALA K++++ I LRY + R
Sbjct: 204 DFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQR 263
Query: 176 GLIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKKHRGIDISDWKDDPNEP 12
G++ + KS N+QRI QN+ +F+FQLT EE+ AI+ N+ R + + + PN P
Sbjct: 264 GVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYP 318
>BC020216-1|AAH20216.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 167 bits (407), Expect = 2e-41
Identities = 91/235 (38%), Positives = 134/235 (57%), Gaps = 14/235 (5%)
Frame = -2
Query: 674 KLWNDKHARXQVVPALQESLKKLGLXYIDLYLIHFPIATKPDDSP-----------DNID 528
KLW + H V PAL+ SLK L L Y+DLYLIHFP++ KP + D +D
Sbjct: 84 KLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVD 143
Query: 527 YLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR--PVINQIEVNPTNTQEPLV 354
TW+ ++ + GLA+SIGVSNFN Q+ +++ ++ PV NQ+E +P Q L+
Sbjct: 144 LCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLL 203
Query: 353 AHCQSLGIAVMAYSPFGFVVSRGQTGAPPP-RSDDPTLTALANKYRKSVGQILLRYLIDR 177
C+S I ++AYS G P +DP L ALA K++++ I LRY + R
Sbjct: 204 DFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQR 263
Query: 176 GLIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKKHRGIDISDWKDDPNEP 12
G++ + KS N+QRI QN+ +F+FQLT EE+ AI+ N+ R + + + PN P
Sbjct: 264 GVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYP 318
>BC015490-1|AAH15490.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 167 bits (407), Expect = 2e-41
Identities = 91/235 (38%), Positives = 134/235 (57%), Gaps = 14/235 (5%)
Frame = -2
Query: 674 KLWNDKHARXQVVPALQESLKKLGLXYIDLYLIHFPIATKPDDSP-----------DNID 528
KLW + H V PAL+ SLK L L Y+DLYLIHFP++ KP + D +D
Sbjct: 84 KLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVD 143
Query: 527 YLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR--PVINQIEVNPTNTQEPLV 354
TW+ ++ + GLA+SIGVSNFN Q+ +++ ++ PV NQ+E +P Q L+
Sbjct: 144 LCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLL 203
Query: 353 AHCQSLGIAVMAYSPFGFVVSRGQTGAPPP-RSDDPTLTALANKYRKSVGQILLRYLIDR 177
C+S I ++AYS G P +DP L ALA K++++ I LRY + R
Sbjct: 204 DFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQR 263
Query: 176 GLIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKKHRGIDISDWKDDPNEP 12
G++ + KS N+QRI QN+ +F+FQLT EE+ AI+ N+ R + + + PN P
Sbjct: 264 GVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYP 318
>BC007024-1|AAH07024.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 167 bits (407), Expect = 2e-41
Identities = 91/235 (38%), Positives = 134/235 (57%), Gaps = 14/235 (5%)
Frame = -2
Query: 674 KLWNDKHARXQVVPALQESLKKLGLXYIDLYLIHFPIATKPDDSP-----------DNID 528
KLW++ H V PAL+ SLK L L Y+DLYLIHFP++ KP + D +D
Sbjct: 84 KLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVD 143
Query: 527 YLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR--PVINQIEVNPTNTQEPLV 354
TW+ M+ + GLA+SIGVSNFN + +++ ++ PV NQ+E +P Q L+
Sbjct: 144 LCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLL 203
Query: 353 AHCQSLGIAVMAYSPFGFVVSRGQTGAPPP-RSDDPTLTALANKYRKSVGQILLRYLIDR 177
C+S I ++AYS G P +DP L ALA K++++ I LRY + R
Sbjct: 204 DFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQR 263
Query: 176 GLIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKKHRGIDISDWKDDPNEP 12
G++ + KS N+QRI QN+ +F+FQLT EE+ AI+ N+ R + + + PN P
Sbjct: 264 GVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYP 318
>AL713867-2|CAI16409.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 167 bits (407), Expect = 2e-41
Identities = 91/235 (38%), Positives = 134/235 (57%), Gaps = 14/235 (5%)
Frame = -2
Query: 674 KLWNDKHARXQVVPALQESLKKLGLXYIDLYLIHFPIATKPDDSP-----------DNID 528
KLW + H V PAL+ SLK L L Y+DLYLIHFP++ KP + D +D
Sbjct: 84 KLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVD 143
Query: 527 YLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR--PVINQIEVNPTNTQEPLV 354
TW+ ++ + GLA+SIGVSNFN Q+ +++ ++ PV NQ+E +P Q L+
Sbjct: 144 LCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLL 203
Query: 353 AHCQSLGIAVMAYSPFGFVVSRGQTGAPPP-RSDDPTLTALANKYRKSVGQILLRYLIDR 177
C+S I ++AYS G P +DP L ALA K++++ I LRY + R
Sbjct: 204 DFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQR 263
Query: 176 GLIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKKHRGIDISDWKDDPNEP 12
G++ + KS N+QRI QN+ +F+FQLT EE+ AI+ N+ R + + + PN P
Sbjct: 264 GVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYP 318
>AL713867-1|CAI16408.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 167 bits (407), Expect = 2e-41
Identities = 91/235 (38%), Positives = 134/235 (57%), Gaps = 14/235 (5%)
Frame = -2
Query: 674 KLWNDKHARXQVVPALQESLKKLGLXYIDLYLIHFPIATKPDDSP-----------DNID 528
KLW++ H V PAL+ SLK L L Y+DLYLIHFP++ KP + D +D
Sbjct: 84 KLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVD 143
Query: 527 YLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR--PVINQIEVNPTNTQEPLV 354
TW+ M+ + GLA+SIGVSNFN + +++ ++ PV NQ+E +P Q L+
Sbjct: 144 LCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLL 203
Query: 353 AHCQSLGIAVMAYSPFGFVVSRGQTGAPPP-RSDDPTLTALANKYRKSVGQILLRYLIDR 177
C+S I ++AYS G P +DP L ALA K++++ I LRY + R
Sbjct: 204 DFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQR 263
Query: 176 GLIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKKHRGIDISDWKDDPNEP 12
G++ + KS N+QRI QN+ +F+FQLT EE+ AI+ N+ R + + + PN P
Sbjct: 264 GVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYP 318
>AL391427-1|CAI14726.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 167 bits (407), Expect = 2e-41
Identities = 91/235 (38%), Positives = 134/235 (57%), Gaps = 14/235 (5%)
Frame = -2
Query: 674 KLWNDKHARXQVVPALQESLKKLGLXYIDLYLIHFPIATKPDDSP-----------DNID 528
KLW++ H V PAL+ SLK L L Y+DLYLIHFP++ KP + D +D
Sbjct: 84 KLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVD 143
Query: 527 YLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR--PVINQIEVNPTNTQEPLV 354
TW+ M+ + GLA+SIGVSNFN + +++ ++ PV NQ+E +P Q L+
Sbjct: 144 LCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLL 203
Query: 353 AHCQSLGIAVMAYSPFGFVVSRGQTGAPPP-RSDDPTLTALANKYRKSVGQILLRYLIDR 177
C+S I ++AYS G P +DP L ALA K++++ I LRY + R
Sbjct: 204 DFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQR 263
Query: 176 GLIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKKHRGIDISDWKDDPNEP 12
G++ + KS N+QRI QN+ +F+FQLT EE+ AI+ N+ R + + + PN P
Sbjct: 264 GVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYP 318
>AB032153-1|BAA92891.1| 323|Homo sapiens bile acid-binding protein
protein.
Length = 323
Score = 167 bits (407), Expect = 2e-41
Identities = 91/235 (38%), Positives = 134/235 (57%), Gaps = 14/235 (5%)
Frame = -2
Query: 674 KLWNDKHARXQVVPALQESLKKLGLXYIDLYLIHFPIATKPDDSP-----------DNID 528
KLW++ H V PAL+ SLK L L Y+DLYLIHFP++ KP + D +D
Sbjct: 84 KLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVD 143
Query: 527 YLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR--PVINQIEVNPTNTQEPLV 354
TW+ M+ + GLA+SIGVSNFN + +++ ++ PV NQ+E +P Q L+
Sbjct: 144 LCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLL 203
Query: 353 AHCQSLGIAVMAYSPFGFVVSRGQTGAPPP-RSDDPTLTALANKYRKSVGQILLRYLIDR 177
C+S I ++AYS G P +DP L ALA K++++ I LRY + R
Sbjct: 204 DFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQR 263
Query: 176 GLIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKKHRGIDISDWKDDPNEP 12
G++ + KS N+QRI QN+ +F+FQLT EE+ AI+ N+ R + + + PN P
Sbjct: 264 GVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYP 318
>AB032150-1|BAA92886.1| 323|Homo sapiens 20 alph-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 167 bits (407), Expect = 2e-41
Identities = 91/235 (38%), Positives = 134/235 (57%), Gaps = 14/235 (5%)
Frame = -2
Query: 674 KLWNDKHARXQVVPALQESLKKLGLXYIDLYLIHFPIATKPDDSP-----------DNID 528
KLW + H V PAL+ SLK L L Y+DLYLIHFP++ KP + D +D
Sbjct: 84 KLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVD 143
Query: 527 YLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR--PVINQIEVNPTNTQEPLV 354
TW+ ++ + GLA+SIGVSNFN Q+ +++ ++ PV NQ+E +P Q L+
Sbjct: 144 LCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLL 203
Query: 353 AHCQSLGIAVMAYSPFGFVVSRGQTGAPPP-RSDDPTLTALANKYRKSVGQILLRYLIDR 177
C+S I ++AYS G P +DP L ALA K++++ I LRY + R
Sbjct: 204 DFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQR 263
Query: 176 GLIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKKHRGIDISDWKDDPNEP 12
G++ + KS N+QRI QN+ +F+FQLT EE+ AI+ N+ R + + + PN P
Sbjct: 264 GVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYP 318
>AB031084-1|BAA92884.1| 323|Homo sapiens bile acid-binding protein
protein.
Length = 323
Score = 167 bits (407), Expect = 2e-41
Identities = 91/235 (38%), Positives = 134/235 (57%), Gaps = 14/235 (5%)
Frame = -2
Query: 674 KLWNDKHARXQVVPALQESLKKLGLXYIDLYLIHFPIATKPDDSP-----------DNID 528
KLW++ H V PAL+ SLK L L Y+DLYLIHFP++ KP + D +D
Sbjct: 84 KLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVD 143
Query: 527 YLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR--PVINQIEVNPTNTQEPLV 354
TW+ M+ + GLA+SIGVSNFN + +++ ++ PV NQ+E +P Q L+
Sbjct: 144 LCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLL 203
Query: 353 AHCQSLGIAVMAYSPFGFVVSRGQTGAPPP-RSDDPTLTALANKYRKSVGQILLRYLIDR 177
C+S I ++AYS G P +DP L ALA K++++ I LRY + R
Sbjct: 204 DFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQR 263
Query: 176 GLIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKKHRGIDISDWKDDPNEP 12
G++ + KS N+QRI QN+ +F+FQLT EE+ AI+ N+ R + + + PN P
Sbjct: 264 GVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYP 318
>AB031083-1|BAA92883.1| 323|Homo sapiens 20 alpha-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 167 bits (407), Expect = 2e-41
Identities = 91/235 (38%), Positives = 134/235 (57%), Gaps = 14/235 (5%)
Frame = -2
Query: 674 KLWNDKHARXQVVPALQESLKKLGLXYIDLYLIHFPIATKPDDSP-----------DNID 528
KLW + H V PAL+ SLK L L Y+DLYLIHFP++ KP + D +D
Sbjct: 84 KLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVD 143
Query: 527 YLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR--PVINQIEVNPTNTQEPLV 354
TW+ ++ + GLA+SIGVSNFN Q+ +++ ++ PV NQ+E +P Q L+
Sbjct: 144 LCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLL 203
Query: 353 AHCQSLGIAVMAYSPFGFVVSRGQTGAPPP-RSDDPTLTALANKYRKSVGQILLRYLIDR 177
C+S I ++AYS G P +DP L ALA K++++ I LRY + R
Sbjct: 204 DFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQR 263
Query: 176 GLIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKKHRGIDISDWKDDPNEP 12
G++ + KS N+QRI QN+ +F+FQLT EE+ AI+ N+ R + + + PN P
Sbjct: 264 GVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYP 318
>AB021654-1|BAA36169.1| 323|Homo sapiens DD2/bile acid-binding
protein/AKR1C2/3alpha-hydroxysteroid dehydrogenase type
3 protein.
Length = 323
Score = 167 bits (407), Expect = 2e-41
Identities = 91/235 (38%), Positives = 134/235 (57%), Gaps = 14/235 (5%)
Frame = -2
Query: 674 KLWNDKHARXQVVPALQESLKKLGLXYIDLYLIHFPIATKPDDSP-----------DNID 528
KLW++ H V PAL+ SLK L L Y+DLYLIHFP++ KP + D +D
Sbjct: 84 KLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVD 143
Query: 527 YLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR--PVINQIEVNPTNTQEPLV 354
TW+ M+ + GLA+SIGVSNFN + +++ ++ PV NQ+E +P Q L+
Sbjct: 144 LCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLL 203
Query: 353 AHCQSLGIAVMAYSPFGFVVSRGQTGAPPP-RSDDPTLTALANKYRKSVGQILLRYLIDR 177
C+S I ++AYS G P +DP L ALA K++++ I LRY + R
Sbjct: 204 DFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQR 263
Query: 176 GLIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKKHRGIDISDWKDDPNEP 12
G++ + KS N+QRI QN+ +F+FQLT EE+ AI+ N+ R + + + PN P
Sbjct: 264 GVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYP 318
>L32592-1|AAB38486.1| 323|Homo sapiens dihydrodiol
dehydrogenase/bile acid-binding protein protein.
Length = 323
Score = 166 bits (403), Expect = 7e-41
Identities = 91/235 (38%), Positives = 133/235 (56%), Gaps = 14/235 (5%)
Frame = -2
Query: 674 KLWNDKHARXQVVPALQESLKKLGLXYIDLYLIHFPIATKPDDSP-----------DNID 528
KLW++ H V PAL+ SLK L L Y DLYLIHFP++ KP + D +D
Sbjct: 84 KLWSNSHRPELVRPALERSLKNLQLDYADLYLIHFPVSVKPGEEVIPKDENGKILFDTVD 143
Query: 527 YLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR--PVINQIEVNPTNTQEPLV 354
TW+ M+ + GLA+SIGVSNFN + +++ ++ PV NQ+E +P Q L+
Sbjct: 144 LCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNEPGLKYEPVCNQVECHPYFNQRKLL 203
Query: 353 AHCQSLGIAVMAYSPFGFVVSRGQTGAPPP-RSDDPTLTALANKYRKSVGQILLRYLIDR 177
C+S I ++AYS G P +DP L ALA K++++ I LRY + R
Sbjct: 204 DFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQR 263
Query: 176 GLIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKKHRGIDISDWKDDPNEP 12
G++ + KS N+QRI QN+ +F+FQLT EE+ AI+ N+ R + + + PN P
Sbjct: 264 GVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYP 318
>S68287-1|AAD14010.1| 323|Homo sapiens chlordecone reductase
protein.
Length = 323
Score = 163 bits (396), Expect = 5e-40
Identities = 89/235 (37%), Positives = 136/235 (57%), Gaps = 14/235 (5%)
Frame = -2
Query: 674 KLWNDKHARXQVVPALQESLKKLGLXYIDLYLIHFPIATKPDDSP-----------DNID 528
KLW V PAL+ SLKKL L Y+DLYL+HFP+A KP ++P D +D
Sbjct: 84 KLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGETPLPKDENGKVIFDTVD 143
Query: 527 YLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR--PVINQIEVNPTNTQEPLV 354
TW+ M+ + GLA+SIGVSNFN Q+ +++ ++ PV NQ+E +P Q L+
Sbjct: 144 LSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPVCNQVECHPYLNQSKLL 203
Query: 353 AHCQSLGIAVMAYSPFGFVVSRGQTGAPPP-RSDDPTLTALANKYRKSVGQILLRYLIDR 177
C+S I ++A+S G + P +DP L ALA K++++ I LRY + R
Sbjct: 204 DFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQR 263
Query: 176 GLIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKKHRGIDISDWKDDPNEP 12
G++ + KS N+QRI +NI +F+FQLT E++ ++ N+ +R + + D P+ P
Sbjct: 264 GVVVLAKSYNEQRIRENIQVFEFQLTSEDMKVLDGLNRNYRYVVMDFLMDHPDYP 318
>M33375-1|AAA35658.1| 308|Homo sapiens protein ( Human chlordecone
reductase mRNA, complete cds. ).
Length = 308
Score = 163 bits (396), Expect = 5e-40
Identities = 89/235 (37%), Positives = 136/235 (57%), Gaps = 14/235 (5%)
Frame = -2
Query: 674 KLWNDKHARXQVVPALQESLKKLGLXYIDLYLIHFPIATKPDDSP-----------DNID 528
KLW V PAL+ SLKKL L Y+DLYL+HFP+A KP ++P D +D
Sbjct: 69 KLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGETPLPKDENGKVIFDTVD 128
Query: 527 YLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR--PVINQIEVNPTNTQEPLV 354
TW+ M+ + GLA+SIGVSNFN Q+ +++ ++ PV NQ+E +P Q L+
Sbjct: 129 LSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPVCNQVECHPYLNQSKLL 188
Query: 353 AHCQSLGIAVMAYSPFGFVVSRGQTGAPPP-RSDDPTLTALANKYRKSVGQILLRYLIDR 177
C+S I ++A+S G + P +DP L ALA K++++ I LRY + R
Sbjct: 189 DFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQR 248
Query: 176 GLIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKKHRGIDISDWKDDPNEP 12
G++ + KS N+QRI +NI +F+FQLT E++ ++ N+ +R + + D P+ P
Sbjct: 249 GVVVLAKSYNEQRIRENIQVFEFQLTSEDMKVLDGLNRNYRYVVMDFLMDHPDYP 303
>D26125-1|BAA05122.1| 321|Homo sapiens 3
alpha-hydroxysteroid/dihydrodiol dehydrogenase DD4
protein.
Length = 321
Score = 163 bits (396), Expect = 5e-40
Identities = 89/235 (37%), Positives = 136/235 (57%), Gaps = 14/235 (5%)
Frame = -2
Query: 674 KLWNDKHARXQVVPALQESLKKLGLXYIDLYLIHFPIATKPDDSP-----------DNID 528
KLW V PAL+ SLKKL L Y+DLYL+HFP+A KP ++P D +D
Sbjct: 82 KLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGETPLPKDENGKVIFDTVD 141
Query: 527 YLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR--PVINQIEVNPTNTQEPLV 354
TW+ M+ + GLA+SIGVSNFN Q+ +++ ++ PV NQ+E +P Q L+
Sbjct: 142 LSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPVCNQVECHPYLNQSKLL 201
Query: 353 AHCQSLGIAVMAYSPFGFVVSRGQTGAPPP-RSDDPTLTALANKYRKSVGQILLRYLIDR 177
C+S I ++A+S G + P +DP L ALA K++++ I LRY + R
Sbjct: 202 DFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQR 261
Query: 176 GLIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKKHRGIDISDWKDDPNEP 12
G++ + KS N+QRI +NI +F+FQLT E++ ++ N+ +R + + D P+ P
Sbjct: 262 GVVVLAKSYNEQRIRENIQVFEFQLTSEDMKVLDGLNRNYRYVVMDFLMDHPDYP 316
>AB045829-1|BAA99542.1| 323|Homo sapiens 3alpha-hydroxysteroid
dehydrogenase variant protein.
Length = 323
Score = 163 bits (396), Expect = 5e-40
Identities = 89/235 (37%), Positives = 136/235 (57%), Gaps = 14/235 (5%)
Frame = -2
Query: 674 KLWNDKHARXQVVPALQESLKKLGLXYIDLYLIHFPIATKPDDSP-----------DNID 528
KLW V PAL+ SLKKL L Y+DLYL+HFP+A KP ++P D +D
Sbjct: 84 KLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGETPLPKDENGKVIFDTVD 143
Query: 527 YLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR--PVINQIEVNPTNTQEPLV 354
TW+ M+ + GLA+SIGVSNFN Q+ +++ ++ PV NQ+E +P Q L+
Sbjct: 144 LCATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPVCNQVECHPYLNQSKLL 203
Query: 353 AHCQSLGIAVMAYSPFGFVVSRGQTGAPPP-RSDDPTLTALANKYRKSVGQILLRYLIDR 177
C+S I ++A+S G + P +DP L ALA K++++ I LRY + R
Sbjct: 204 DFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQR 263
Query: 176 GLIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKKHRGIDISDWKDDPNEP 12
G++ + KS N+QRI +NI +F+FQLT E++ ++ N+ +R + + D P+ P
Sbjct: 264 GVVVLAKSYNEQRIRENIQVFEFQLTSEDMKVLDGLNRNYRYVVMDFVMDHPDYP 318
>AB032163-1|BAA92893.1| 323|Homo sapiens dihydrodiol dehydrogenase
4 protein.
Length = 323
Score = 163 bits (396), Expect = 5e-40
Identities = 89/235 (37%), Positives = 136/235 (57%), Gaps = 14/235 (5%)
Frame = -2
Query: 674 KLWNDKHARXQVVPALQESLKKLGLXYIDLYLIHFPIATKPDDSP-----------DNID 528
KLW V PAL+ SLKKL L Y+DLYL+HFP+A KP ++P D +D
Sbjct: 84 KLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGETPLPKDENGKVIFDTVD 143
Query: 527 YLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR--PVINQIEVNPTNTQEPLV 354
TW+ M+ + GLA+SIGVSNFN Q+ +++ ++ PV NQ+E +P Q L+
Sbjct: 144 LSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPVCNQVECHPYLNQSKLL 203
Query: 353 AHCQSLGIAVMAYSPFGFVVSRGQTGAPPP-RSDDPTLTALANKYRKSVGQILLRYLIDR 177
C+S I ++A+S G + P +DP L ALA K++++ I LRY + R
Sbjct: 204 DFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQR 263
Query: 176 GLIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKKHRGIDISDWKDDPNEP 12
G++ + KS N+QRI +NI +F+FQLT E++ ++ N+ +R + + D P+ P
Sbjct: 264 GVVVLAKSYNEQRIRENIQVFEFQLTSEDMKVLDGLNRNYRYVVMDFLMDHPDYP 318
>AB031085-1|BAA92885.1| 323|Homo sapiens dihydrodiol dehydrogenase
4 protein.
Length = 323
Score = 163 bits (396), Expect = 5e-40
Identities = 89/235 (37%), Positives = 136/235 (57%), Gaps = 14/235 (5%)
Frame = -2
Query: 674 KLWNDKHARXQVVPALQESLKKLGLXYIDLYLIHFPIATKPDDSP-----------DNID 528
KLW V PAL+ SLKKL L Y+DLYL+HFP+A KP ++P D +D
Sbjct: 84 KLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGETPLPKDENGKVIFDTVD 143
Query: 527 YLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR--PVINQIEVNPTNTQEPLV 354
TW+ M+ + GLA+SIGVSNFN Q+ +++ ++ PV NQ+E +P Q L+
Sbjct: 144 LSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPVCNQVECHPYLNQSKLL 203
Query: 353 AHCQSLGIAVMAYSPFGFVVSRGQTGAPPP-RSDDPTLTALANKYRKSVGQILLRYLIDR 177
C+S I ++A+S G + P +DP L ALA K++++ I LRY + R
Sbjct: 204 DFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQR 263
Query: 176 GLIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKKHRGIDISDWKDDPNEP 12
G++ + KS N+QRI +NI +F+FQLT E++ ++ N+ +R + + D P+ P
Sbjct: 264 GVVVLAKSYNEQRIRENIQVFEFQLTSEDMKVLDGLNRNYRYVVMDFLMDHPDYP 318
>S68290-1|AAD14012.1| 320|Homo sapiens chlordecone reductase
homolog protein.
Length = 320
Score = 163 bits (395), Expect = 7e-40
Identities = 88/235 (37%), Positives = 133/235 (56%), Gaps = 14/235 (5%)
Frame = -2
Query: 674 KLWNDKHARXQVVPALQESLKKLGLXYIDLYLIHFPIATKPDDSP-----------DNID 528
KLW + H PAL+ SLK L L Y+DLYLIHFP++ KP + D +D
Sbjct: 81 KLWCNSHRPELDRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVD 140
Query: 527 YLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNS--YIRPVINQIEVNPTNTQEPLV 354
TW+ ++ + LA+SIGVSNFN + + +++ ++PV NQ+E +P Q L+
Sbjct: 141 LCATWEAVEKCKDAELAKSIGVSNFNRSTLEMILNKPGLQVKPVCNQVECHPYFNQRKLL 200
Query: 353 AHCQSLGIAVMAYSPFGFVVSRGQTGAPPP-RSDDPTLTALANKYRKSVGQILLRYLIDR 177
C+S I ++AYS G + P +DP L ALA K++++ I LRY + R
Sbjct: 201 DFCKSKDIVLVAYSALGSLREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQR 260
Query: 176 GLIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKKHRGIDISDWKDDPNEP 12
G++ + KS N+QRI QN+ +F+FQLT EE+ AI+ N+ R + + + PN P
Sbjct: 261 GVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYP 315
>AL355303-2|CAI14202.1| 323|Homo sapiens aldo-keto reductase family
1, member C4 (chlordecone reductase; 3-alpha hydroxy
protein.
Length = 323
Score = 163 bits (395), Expect = 7e-40
Identities = 89/235 (37%), Positives = 136/235 (57%), Gaps = 14/235 (5%)
Frame = -2
Query: 674 KLWNDKHARXQVVPALQESLKKLGLXYIDLYLIHFPIATKPDDSP-----------DNID 528
KLW V PAL+ SLKKL L Y+DLYL+HFP+A KP ++P D +D
Sbjct: 84 KLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGETPLPKDENGKVIFDTVD 143
Query: 527 YLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR--PVINQIEVNPTNTQEPLV 354
TW+ M+ + GLA+SIGVSNFN Q+ +++ ++ PV NQ+E +P Q L+
Sbjct: 144 LSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPVCNQVECHPYLNQSKLL 203
Query: 353 AHCQSLGIAVMAYSPFGFVVSRGQTGAPPP-RSDDPTLTALANKYRKSVGQILLRYLIDR 177
C+S I ++A+S G + P +DP L ALA K++++ I LRY + R
Sbjct: 204 DFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLEDPVLCALAKKHKQTPALIALRYQLQR 263
Query: 176 GLIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKKHRGIDISDWKDDPNEP 12
G++ + KS N+QRI +NI +F+FQLT E++ ++ N+ +R + + D P+ P
Sbjct: 264 GVVVLAKSYNEQRIRENIQVFEFQLTSEDMKVLDGLNRNYRYVVMDFLMDHPDYP 318
>BC020744-1|AAH20744.1| 323|Homo sapiens aldo-keto reductase family
1, member C4 (chlordecone reductase; 3-alpha hydroxy
protein.
Length = 323
Score = 162 bits (394), Expect = 9e-40
Identities = 89/235 (37%), Positives = 136/235 (57%), Gaps = 14/235 (5%)
Frame = -2
Query: 674 KLWNDKHARXQVVPALQESLKKLGLXYIDLYLIHFPIATKPDDSP-----------DNID 528
KLW V PAL+ SLKKL L Y+DLYL+HFP+A KP ++P D +D
Sbjct: 84 KLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGETPLPKDENGKVIFDTVD 143
Query: 527 YLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR--PVINQIEVNPTNTQEPLV 354
TW+ M+ + GLA+SIGVSNFN Q+ +++ ++ PV NQ+E +P Q L+
Sbjct: 144 LSATWEVMEKCKDAGLAKSIGVSNFNYRQLEMILNKPGLKYKPVCNQVECHPYLNQSKLL 203
Query: 353 AHCQSLGIAVMAYSPFGFVVSRGQTGAPPP-RSDDPTLTALANKYRKSVGQILLRYLIDR 177
C+S I ++A+S G + P +DP L ALA K++++ I LRY + R
Sbjct: 204 DFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQR 263
Query: 176 GLIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKKHRGIDISDWKDDPNEP 12
G++ + KS N+QRI +NI +F+FQLT E++ ++ N+ +R + + D P+ P
Sbjct: 264 GVVVLAKSYNEQRIRENIQVFEFQLTSEDMKVLDGLNRNYRYVVMDFLMDHPDYP 318
>Z28339-1|CAA82193.1| 326|Homo sapiens delta 4-3-oxosteroid 5
beta-reductase protein.
Length = 326
Score = 162 bits (393), Expect = 1e-39
Identities = 91/237 (38%), Positives = 130/237 (54%), Gaps = 16/237 (6%)
Frame = -2
Query: 674 KLWNDKHARXQVVPALQESLKKLGLXYIDLYLIHFPIATKPDDS----PDNIDYL----- 522
KLW H V P L+ +L+ L L Y+DLY+I P+A KP D +N +L
Sbjct: 87 KLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPGDEIYPRDENGKWLYHKSN 146
Query: 521 --ETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR--PVINQIEVNPTNTQEPLV 354
TW+ M+ + GL +S+GVSNFN Q+ +++ ++ PV NQ+E +P TQ L+
Sbjct: 147 LCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKPVSNQVECHPYFTQPKLL 206
Query: 353 AHCQSLGIAVMAYSPFGFVVSRGQTG---APPPRSDDPTLTALANKYRKSVGQILLRYLI 183
CQ I + AYSP G SR + PP D L +L +Y K+ QI+LR+ I
Sbjct: 207 KFCQQHDIVITAYSPLG--TSRNPIWVNVSSPPLLKDALLNSLGKRYNKTAAQIVLRFNI 264
Query: 182 DRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKKHRGIDISDWKDDPNEP 12
RG++ IPKS N +RI +N +FDF LT EE+ I NK R +++ W+D P P
Sbjct: 265 QRGVVVIPKSFNLERIKENFQIFDFSLTEEEMKDIEALNKNVRFVELLMWRDHPEYP 321
>BC130627-1|AAI30628.1| 326|Homo sapiens aldo-keto reductase family
1, member D1 (delta 4-3-ketosteroid-5-beta-reductase
protein.
Length = 326
Score = 162 bits (393), Expect = 1e-39
Identities = 91/237 (38%), Positives = 130/237 (54%), Gaps = 16/237 (6%)
Frame = -2
Query: 674 KLWNDKHARXQVVPALQESLKKLGLXYIDLYLIHFPIATKPDDS----PDNIDYL----- 522
KLW H V P L+ +L+ L L Y+DLY+I P+A KP D +N +L
Sbjct: 87 KLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPGDEIYPRDENGKWLYHKSN 146
Query: 521 --ETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR--PVINQIEVNPTNTQEPLV 354
TW+ M+ + GL +S+GVSNFN Q+ +++ ++ PV NQ+E +P TQ L+
Sbjct: 147 LCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKPVSNQVECHPYFTQPKLL 206
Query: 353 AHCQSLGIAVMAYSPFGFVVSRGQTG---APPPRSDDPTLTALANKYRKSVGQILLRYLI 183
CQ I + AYSP G SR + PP D L +L +Y K+ QI+LR+ I
Sbjct: 207 KFCQQHDIVITAYSPLG--TSRNPIWVNVSSPPLLKDALLNSLGKRYNKTAAQIVLRFNI 264
Query: 182 DRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKKHRGIDISDWKDDPNEP 12
RG++ IPKS N +RI +N +FDF LT EE+ I NK R +++ W+D P P
Sbjct: 265 QRGVVVIPKSFNLERIKENFQIFDFSLTEEEMKDIEALNKNVRFVELLMWRDHPEYP 321
>BC130625-1|AAI30626.1| 326|Homo sapiens aldo-keto reductase family
1, member D1 (delta 4-3-ketosteroid-5-beta-reductase
protein.
Length = 326
Score = 162 bits (393), Expect = 1e-39
Identities = 91/237 (38%), Positives = 130/237 (54%), Gaps = 16/237 (6%)
Frame = -2
Query: 674 KLWNDKHARXQVVPALQESLKKLGLXYIDLYLIHFPIATKPDDS----PDNIDYL----- 522
KLW H V P L+ +L+ L L Y+DLY+I P+A KP D +N +L
Sbjct: 87 KLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPGDEIYPRDENGKWLYHKSN 146
Query: 521 --ETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR--PVINQIEVNPTNTQEPLV 354
TW+ M+ + GL +S+GVSNFN Q+ +++ ++ PV NQ+E +P TQ L+
Sbjct: 147 LCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKPVSNQVECHPYFTQPKLL 206
Query: 353 AHCQSLGIAVMAYSPFGFVVSRGQTG---APPPRSDDPTLTALANKYRKSVGQILLRYLI 183
CQ I + AYSP G SR + PP D L +L +Y K+ QI+LR+ I
Sbjct: 207 KFCQQHDIVITAYSPLG--TSRNPIWVNVSSPPLLKDALLNSLGKRYNKTAAQIVLRFNI 264
Query: 182 DRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKKHRGIDISDWKDDPNEP 12
RG++ IPKS N +RI +N +FDF LT EE+ I NK R +++ W+D P P
Sbjct: 265 QRGVVVIPKSFNLERIKENFQIFDFSLTEEEMKDIEALNKNVRFVELLMWRDHPEYP 321
>AF283659-1|AAG39381.1| 326|Homo sapiens 5-beta steroid reductase
protein.
Length = 326
Score = 162 bits (393), Expect = 1e-39
Identities = 91/237 (38%), Positives = 130/237 (54%), Gaps = 16/237 (6%)
Frame = -2
Query: 674 KLWNDKHARXQVVPALQESLKKLGLXYIDLYLIHFPIATKPDDS----PDNIDYL----- 522
KLW H V P L+ +L+ L L Y+DLY+I P+A KP D +N +L
Sbjct: 87 KLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPGDEIYPRDENGKWLYHKSN 146
Query: 521 --ETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR--PVINQIEVNPTNTQEPLV 354
TW+ M+ + GL +S+GVSNFN Q+ +++ ++ PV NQ+E +P TQ L+
Sbjct: 147 LCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKPVSNQVECHPYFTQPKLL 206
Query: 353 AHCQSLGIAVMAYSPFGFVVSRGQTG---APPPRSDDPTLTALANKYRKSVGQILLRYLI 183
CQ I + AYSP G SR + PP D L +L +Y K+ QI+LR+ I
Sbjct: 207 KFCQQHDIVITAYSPLG--TSRNPIWVNVSSPPLLKDALLNSLGKRYNKTAAQIVLRFNI 264
Query: 182 DRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKKHRGIDISDWKDDPNEP 12
RG++ IPKS N +RI +N +FDF LT EE+ I NK R +++ W+D P P
Sbjct: 265 QRGVVVIPKSFNLERIKENFQIFDFSLTEEEMKDIEALNKNVRFVELLMWRDHPEYP 321
>CR542203-1|CAG47000.1| 316|Homo sapiens AKR1B1 protein.
Length = 316
Score = 161 bits (390), Expect = 3e-39
Identities = 84/220 (38%), Positives = 129/220 (58%), Gaps = 13/220 (5%)
Frame = -2
Query: 674 KLWNDKHARXQVVPALQESLKKLGLXYIDLYLIHFPIATKP-------DDS----PDNID 528
KLW H + V A Q++L L L Y+DLYLIH+PI KP D+S P + +
Sbjct: 78 KLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPIGFKPGKEFFPLDESGNVVPSDTN 137
Query: 527 YLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR--PVINQIEVNPTNTQEPLV 354
L+TW M++ GL ++IG+SNFN Q+ +++ ++ P +NQIE +P TQE L+
Sbjct: 138 ILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLI 197
Query: 353 AHCQSLGIAVMAYSPFGFVVSRGQTGAPPPRSDDPTLTALANKYRKSVGQILLRYLIDRG 174
+CQS GI V AYSP G P +DP + A+A K+ K+ Q+L+R+ + R
Sbjct: 198 QYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRN 257
Query: 173 LIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKKHR 54
L+ IPKS +RIA+N +FDF+L+ +++ + +N+ R
Sbjct: 258 LVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWR 297
>DQ269985-1|ABB76132.1| 323|Homo sapiens type II 3a-hydroxysteroid
dehydrogenase variant protein.
Length = 323
Score = 159 bits (387), Expect = 6e-39
Identities = 89/235 (37%), Positives = 134/235 (57%), Gaps = 14/235 (5%)
Frame = -2
Query: 674 KLWNDKHARXQVVPALQESLKKLGLXYIDLYLIHFPIATKPDD--SP---------DNID 528
KLW + H V PAL+ SLKK L Y+DLYLIH P++ KP + SP D +D
Sbjct: 84 KLWCNSHRPELVRPALERSLKKAQLDYVDLYLIHSPMSLKPGEELSPTDENGKVIFDIVD 143
Query: 527 YLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR--PVINQIEVNPTNTQEPLV 354
TW+ M+ + GLA+SIGVSNFN Q+ +++ ++ PV NQ+E +P + L+
Sbjct: 144 LCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLL 203
Query: 353 AHCQSLGIAVMAYSPFGFVVSRGQTGAPPP-RSDDPTLTALANKYRKSVGQILLRYLIDR 177
C+S I ++AYS G + P +DP L ALA K++++ I LRY + R
Sbjct: 204 DFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQR 263
Query: 176 GLIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKKHRGIDISDWKDDPNEP 12
G++ + KS N+QRI QN+ +F+FQLT E++ AI+ ++ + + PN P
Sbjct: 264 GVVVLAKSYNEQRIRQNVQVFEFQLTAEDMKAIDGLDRNLHYFNSDSFASHPNYP 318
>D17793-1|BAA04619.2| 325|Homo sapiens KIAA0119 protein.
Length = 325
Score = 159 bits (386), Expect = 8e-39
Identities = 89/235 (37%), Positives = 134/235 (57%), Gaps = 14/235 (5%)
Frame = -2
Query: 674 KLWNDKHARXQVVPALQESLKKLGLXYIDLYLIHFPIATKPDD--SP---------DNID 528
KLW+ H V PAL+ SLKK L Y+DLYLIH P++ KP + SP D +D
Sbjct: 86 KLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEELSPTDENGKVIFDIVD 145
Query: 527 YLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR--PVINQIEVNPTNTQEPLV 354
TW+ M+ + GLA+SIGVSNFN Q+ +++ ++ PV NQ+E +P + L+
Sbjct: 146 LCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLL 205
Query: 353 AHCQSLGIAVMAYSPFGFVVSRGQTGAPPP-RSDDPTLTALANKYRKSVGQILLRYLIDR 177
C+S I ++AYS G + P +DP L ALA K++++ I LRY + R
Sbjct: 206 DFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQR 265
Query: 176 GLIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKKHRGIDISDWKDDPNEP 12
G++ + KS N+QRI QN+ +F+FQLT E++ AI+ ++ + + PN P
Sbjct: 266 GVVVLAKSYNEQRIRQNVQVFEFQLTAEDMKAIDGLDRNLHYFNSDSFASHPNYP 320
>BT007286-1|AAP35950.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 159 bits (386), Expect = 8e-39
Identities = 89/235 (37%), Positives = 134/235 (57%), Gaps = 14/235 (5%)
Frame = -2
Query: 674 KLWNDKHARXQVVPALQESLKKLGLXYIDLYLIHFPIATKPDD--SP---------DNID 528
KLW+ H V PAL+ SLKK L Y+DLYLIH P++ KP + SP D +D
Sbjct: 84 KLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEELSPTDENGKVIFDIVD 143
Query: 527 YLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR--PVINQIEVNPTNTQEPLV 354
TW+ M+ + GLA+SIGVSNFN Q+ +++ ++ PV NQ+E +P + L+
Sbjct: 144 LCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLL 203
Query: 353 AHCQSLGIAVMAYSPFGFVVSRGQTGAPPP-RSDDPTLTALANKYRKSVGQILLRYLIDR 177
C+S I ++AYS G + P +DP L ALA K++++ I LRY + R
Sbjct: 204 DFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQR 263
Query: 176 GLIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKKHRGIDISDWKDDPNEP 12
G++ + KS N+QRI QN+ +F+FQLT E++ AI+ ++ + + PN P
Sbjct: 264 GVVVLAKSYNEQRIRQNVQVFEFQLTAEDMKAIDGLDRNLHYFNSDSFASHPNYP 318
>BC019230-1|AAH19230.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 159 bits (386), Expect = 8e-39
Identities = 89/235 (37%), Positives = 134/235 (57%), Gaps = 14/235 (5%)
Frame = -2
Query: 674 KLWNDKHARXQVVPALQESLKKLGLXYIDLYLIHFPIATKPDD--SP---------DNID 528
KLW+ H V PAL+ SLKK L Y+DLYLIH P++ KP + SP D +D
Sbjct: 84 KLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEELSPTDENGKVIFDIVD 143
Query: 527 YLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR--PVINQIEVNPTNTQEPLV 354
TW+ M+ + GLA+SIGVSNFN Q+ +++ ++ PV NQ+E +P + L+
Sbjct: 144 LCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLL 203
Query: 353 AHCQSLGIAVMAYSPFGFVVSRGQTGAPPP-RSDDPTLTALANKYRKSVGQILLRYLIDR 177
C+S I ++AYS G + P +DP L ALA K++++ I LRY + R
Sbjct: 204 DFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQR 263
Query: 176 GLIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKKHRGIDISDWKDDPNEP 12
G++ + KS N+QRI QN+ +F+FQLT E++ AI+ ++ + + PN P
Sbjct: 264 GVVVLAKSYNEQRIRQNVQVFEFQLTAEDMKAIDGLDRNLHYFNSDSFASHPNYP 318
>BC001479-1|AAH01479.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 159 bits (386), Expect = 8e-39
Identities = 89/235 (37%), Positives = 134/235 (57%), Gaps = 14/235 (5%)
Frame = -2
Query: 674 KLWNDKHARXQVVPALQESLKKLGLXYIDLYLIHFPIATKPDD--SP---------DNID 528
KLW+ H V PAL+ SLKK L Y+DLYLIH P++ KP + SP D +D
Sbjct: 84 KLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEELSPTDENGKVIFDIVD 143
Query: 527 YLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR--PVINQIEVNPTNTQEPLV 354
TW+ M+ + GLA+SIGVSNFN Q+ +++ ++ PV NQ+E +P + L+
Sbjct: 144 LCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLL 203
Query: 353 AHCQSLGIAVMAYSPFGFVVSRGQTGAPPP-RSDDPTLTALANKYRKSVGQILLRYLIDR 177
C+S I ++AYS G + P +DP L ALA K++++ I LRY + R
Sbjct: 204 DFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQR 263
Query: 176 GLIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKKHRGIDISDWKDDPNEP 12
G++ + KS N+QRI QN+ +F+FQLT E++ AI+ ++ + + PN P
Sbjct: 264 GVVVLAKSYNEQRIRQNVQVFEFQLTAEDMKAIDGLDRNLHYFNSDSFASHPNYP 318
>AL391427-4|CAI14729.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 159 bits (386), Expect = 8e-39
Identities = 89/235 (37%), Positives = 134/235 (57%), Gaps = 14/235 (5%)
Frame = -2
Query: 674 KLWNDKHARXQVVPALQESLKKLGLXYIDLYLIHFPIATKPDD--SP---------DNID 528
KLW+ H V PAL+ SLKK L Y+DLYLIH P++ KP + SP D +D
Sbjct: 84 KLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEELSPTDENGKVIFDIVD 143
Query: 527 YLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR--PVINQIEVNPTNTQEPLV 354
TW+ M+ + GLA+SIGVSNFN Q+ +++ ++ PV NQ+E +P + L+
Sbjct: 144 LCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLL 203
Query: 353 AHCQSLGIAVMAYSPFGFVVSRGQTGAPPP-RSDDPTLTALANKYRKSVGQILLRYLIDR 177
C+S I ++AYS G + P +DP L ALA K++++ I LRY + R
Sbjct: 204 DFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQR 263
Query: 176 GLIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKKHRGIDISDWKDDPNEP 12
G++ + KS N+QRI QN+ +F+FQLT E++ AI+ ++ + + PN P
Sbjct: 264 GVVVLAKSYNEQRIRQNVQVFEFQLTAEDMKAIDGLDRNLHYFNSDSFASHPNYP 318
>AF149416-1|AAF07272.2| 323|Homo sapiens 3-alpha hydroxysteroid
dehydrogenase type IIb protein.
Length = 323
Score = 159 bits (386), Expect = 8e-39
Identities = 88/235 (37%), Positives = 134/235 (57%), Gaps = 14/235 (5%)
Frame = -2
Query: 674 KLWNDKHARXQVVPALQESLKKLGLXYIDLYLIHFPIATKPDD--SP---------DNID 528
KLW+ H V PAL+ SLKK L Y+DLYLIH P++ KP + SP D +D
Sbjct: 84 KLWSTSHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEELSPTDENGKVIFDIVD 143
Query: 527 YLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR--PVINQIEVNPTNTQEPLV 354
TW+ M+ + GLA+SIGVSNFN Q+ +++ ++ PV NQ+E +P + L+
Sbjct: 144 LCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLL 203
Query: 353 AHCQSLGIAVMAYSPFGFVVSRGQTGAPPP-RSDDPTLTALANKYRKSVGQILLRYLIDR 177
C+S I ++AYS G + P +DP L ALA K++++ I LRY + R
Sbjct: 204 DFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQR 263
Query: 176 GLIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKKHRGIDISDWKDDPNEP 12
G++ + +S N+QRI QN+ +F+FQLT E++ AI+ ++ + + PN P
Sbjct: 264 GVVVLARSYNEQRIRQNVQVFEFQLTAEDMKAIDGLDRNLHYFNSDSFASHPNYP 318
>AB032157-1|BAA92892.1| 323|Homo sapiens prostaglandin F synthase
protein.
Length = 323
Score = 159 bits (386), Expect = 8e-39
Identities = 89/235 (37%), Positives = 134/235 (57%), Gaps = 14/235 (5%)
Frame = -2
Query: 674 KLWNDKHARXQVVPALQESLKKLGLXYIDLYLIHFPIATKPDD--SP---------DNID 528
KLW+ H V PAL+ SLKK L Y+DLYLIH P++ KP + SP D +D
Sbjct: 84 KLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEELSPTDENGKVIFDIVD 143
Query: 527 YLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR--PVINQIEVNPTNTQEPLV 354
TW+ M+ + GLA+SIGVSNFN Q+ +++ ++ PV NQ+E +P + L+
Sbjct: 144 LCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLL 203
Query: 353 AHCQSLGIAVMAYSPFGFVVSRGQTGAPPP-RSDDPTLTALANKYRKSVGQILLRYLIDR 177
C+S I ++AYS G + P +DP L ALA K++++ I LRY + R
Sbjct: 204 DFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQR 263
Query: 176 GLIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKKHRGIDISDWKDDPNEP 12
G++ + KS N+QRI QN+ +F+FQLT E++ AI+ ++ + + PN P
Sbjct: 264 GVVVLAKSYNEQRIRQNVQVFEFQLTAEDMKAIDGLDRNLHYFNSDSFASHPNYP 318
>AB018580-1|BAA88488.1| 323|Homo sapiens hluPGFS protein.
Length = 323
Score = 159 bits (386), Expect = 8e-39
Identities = 89/235 (37%), Positives = 134/235 (57%), Gaps = 14/235 (5%)
Frame = -2
Query: 674 KLWNDKHARXQVVPALQESLKKLGLXYIDLYLIHFPIATKPDD--SP---------DNID 528
KLW+ H V PAL+ SLKK L Y+DLYLIH P++ KP + SP D +D
Sbjct: 84 KLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEELSPTDENGKVIFDIVD 143
Query: 527 YLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR--PVINQIEVNPTNTQEPLV 354
TW+ M+ + GLA+SIGVSNFN Q+ +++ ++ PV NQ+E +P + L+
Sbjct: 144 LCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLL 203
Query: 353 AHCQSLGIAVMAYSPFGFVVSRGQTGAPPP-RSDDPTLTALANKYRKSVGQILLRYLIDR 177
C+S I ++AYS G + P +DP L ALA K++++ I LRY + R
Sbjct: 204 DFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQR 263
Query: 176 GLIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKKHRGIDISDWKDDPNEP 12
G++ + KS N+QRI QN+ +F+FQLT E++ AI+ ++ + + PN P
Sbjct: 264 GVVVLAKSYNEQRIRQNVQVFEFQLTAEDMKAIDGLDRNLHYFNSDSFASHPNYP 318
>X15414-1|CAA33460.1| 316|Homo sapiens protein ( Human mRNA for
aldose reductase (EC 1.1.1.2). ).
Length = 316
Score = 159 bits (385), Expect = 1e-38
Identities = 83/220 (37%), Positives = 128/220 (58%), Gaps = 13/220 (5%)
Frame = -2
Query: 674 KLWNDKHARXQVVPALQESLKKLGLXYIDLYLIHFPIATKP-------DDS----PDNID 528
KLW H + V A Q++L L L Y+DLYLIH+P KP D+S P + +
Sbjct: 78 KLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTN 137
Query: 527 YLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR--PVINQIEVNPTNTQEPLV 354
L+TW M++ GL ++IG+SNFN Q+ +++ ++ P +NQIE +P TQE L+
Sbjct: 138 ILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLI 197
Query: 353 AHCQSLGIAVMAYSPFGFVVSRGQTGAPPPRSDDPTLTALANKYRKSVGQILLRYLIDRG 174
+CQS GI V AYSP G P +DP + A+A K+ K+ Q+L+R+ + R
Sbjct: 198 QYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRN 257
Query: 173 LIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKKHR 54
L+ IPKS +RIA+N +FDF+L+ +++ + +N+ R
Sbjct: 258 LVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWR 297
>M59783-1|AAA51712.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 159 bits (385), Expect = 1e-38
Identities = 83/220 (37%), Positives = 128/220 (58%), Gaps = 13/220 (5%)
Frame = -2
Query: 674 KLWNDKHARXQVVPALQESLKKLGLXYIDLYLIHFPIATKP-------DDS----PDNID 528
KLW H + V A Q++L L L Y+DLYLIH+P KP D+S P + +
Sbjct: 78 KLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTN 137
Query: 527 YLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR--PVINQIEVNPTNTQEPLV 354
L+TW M++ GL ++IG+SNFN Q+ +++ ++ P +NQIE +P TQE L+
Sbjct: 138 ILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLI 197
Query: 353 AHCQSLGIAVMAYSPFGFVVSRGQTGAPPPRSDDPTLTALANKYRKSVGQILLRYLIDRG 174
+CQS GI V AYSP G P +DP + A+A K+ K+ Q+L+R+ + R
Sbjct: 198 QYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRN 257
Query: 173 LIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKKHR 54
L+ IPKS +RIA+N +FDF+L+ +++ + +N+ R
Sbjct: 258 LVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWR 297
>M34720-1|AAA35560.1| 316|Homo sapiens protein ( Human aldose
reductase mRNA, complete cds. ).
Length = 316
Score = 159 bits (385), Expect = 1e-38
Identities = 83/220 (37%), Positives = 128/220 (58%), Gaps = 13/220 (5%)
Frame = -2
Query: 674 KLWNDKHARXQVVPALQESLKKLGLXYIDLYLIHFPIATKP-------DDS----PDNID 528
KLW H + V A Q++L L L Y+DLYLIH+P KP D+S P + +
Sbjct: 78 KLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTN 137
Query: 527 YLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR--PVINQIEVNPTNTQEPLV 354
L+TW M++ GL ++IG+SNFN Q+ +++ ++ P +NQIE +P TQE L+
Sbjct: 138 ILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLI 197
Query: 353 AHCQSLGIAVMAYSPFGFVVSRGQTGAPPPRSDDPTLTALANKYRKSVGQILLRYLIDRG 174
+CQS GI V AYSP G P +DP + A+A K+ K+ Q+L+R+ + R
Sbjct: 198 QYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRN 257
Query: 173 LIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKKHR 54
L+ IPKS +RIA+N +FDF+L+ +++ + +N+ R
Sbjct: 258 LVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWR 297
>J05474-1|AAA51715.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 159 bits (385), Expect = 1e-38
Identities = 83/220 (37%), Positives = 128/220 (58%), Gaps = 13/220 (5%)
Frame = -2
Query: 674 KLWNDKHARXQVVPALQESLKKLGLXYIDLYLIHFPIATKP-------DDS----PDNID 528
KLW H + V A Q++L L L Y+DLYLIH+P KP D+S P + +
Sbjct: 78 KLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTN 137
Query: 527 YLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR--PVINQIEVNPTNTQEPLV 354
L+TW M++ GL ++IG+SNFN Q+ +++ ++ P +NQIE +P TQE L+
Sbjct: 138 ILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLI 197
Query: 353 AHCQSLGIAVMAYSPFGFVVSRGQTGAPPPRSDDPTLTALANKYRKSVGQILLRYLIDRG 174
+CQS GI V AYSP G P +DP + A+A K+ K+ Q+L+R+ + R
Sbjct: 198 QYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRN 257
Query: 173 LIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKKHR 54
L+ IPKS +RIA+N +FDF+L+ +++ + +N+ R
Sbjct: 258 LVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWR 297
>J05017-1|AAA51714.1| 316|Homo sapiens ALDR1 protein.
Length = 316
Score = 159 bits (385), Expect = 1e-38
Identities = 83/220 (37%), Positives = 128/220 (58%), Gaps = 13/220 (5%)
Frame = -2
Query: 674 KLWNDKHARXQVVPALQESLKKLGLXYIDLYLIHFPIATKP-------DDS----PDNID 528
KLW H + V A Q++L L L Y+DLYLIH+P KP D+S P + +
Sbjct: 78 KLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTN 137
Query: 527 YLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR--PVINQIEVNPTNTQEPLV 354
L+TW M++ GL ++IG+SNFN Q+ +++ ++ P +NQIE +P TQE L+
Sbjct: 138 ILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLI 197
Query: 353 AHCQSLGIAVMAYSPFGFVVSRGQTGAPPPRSDDPTLTALANKYRKSVGQILLRYLIDRG 174
+CQS GI V AYSP G P +DP + A+A K+ K+ Q+L+R+ + R
Sbjct: 198 QYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRN 257
Query: 173 LIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKKHR 54
L+ IPKS +RIA+N +FDF+L+ +++ + +N+ R
Sbjct: 258 LVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWR 297
>J04795-1|AAA51713.1| 316|Homo sapiens ALDR1 protein.
Length = 316
Score = 159 bits (385), Expect = 1e-38
Identities = 83/220 (37%), Positives = 128/220 (58%), Gaps = 13/220 (5%)
Frame = -2
Query: 674 KLWNDKHARXQVVPALQESLKKLGLXYIDLYLIHFPIATKP-------DDS----PDNID 528
KLW H + V A Q++L L L Y+DLYLIH+P KP D+S P + +
Sbjct: 78 KLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTN 137
Query: 527 YLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR--PVINQIEVNPTNTQEPLV 354
L+TW M++ GL ++IG+SNFN Q+ +++ ++ P +NQIE +P TQE L+
Sbjct: 138 ILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLI 197
Query: 353 AHCQSLGIAVMAYSPFGFVVSRGQTGAPPPRSDDPTLTALANKYRKSVGQILLRYLIDRG 174
+CQS GI V AYSP G P +DP + A+A K+ K+ Q+L+R+ + R
Sbjct: 198 QYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRN 257
Query: 173 LIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKKHR 54
L+ IPKS +RIA+N +FDF+L+ +++ + +N+ R
Sbjct: 258 LVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWR 297
>CR450351-1|CAG29347.1| 316|Homo sapiens AKR1B1 protein.
Length = 316
Score = 159 bits (385), Expect = 1e-38
Identities = 83/220 (37%), Positives = 128/220 (58%), Gaps = 13/220 (5%)
Frame = -2
Query: 674 KLWNDKHARXQVVPALQESLKKLGLXYIDLYLIHFPIATKP-------DDS----PDNID 528
KLW H + V A Q++L L L Y+DLYLIH+P +P D+S P + +
Sbjct: 78 KLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFRPGKEFFPLDESGNVVPSDTN 137
Query: 527 YLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR--PVINQIEVNPTNTQEPLV 354
L+TW M++ GL ++IG+SNFN Q+ ++S ++ P +NQIE +P TQE L+
Sbjct: 138 ILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILSKPGLKYKPAVNQIECHPYLTQEKLI 197
Query: 353 AHCQSLGIAVMAYSPFGFVVSRGQTGAPPPRSDDPTLTALANKYRKSVGQILLRYLIDRG 174
+CQS GI V AYSP G P +DP + A+A K+ K+ Q+L+R+ + R
Sbjct: 198 QYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRN 257
Query: 173 LIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKKHR 54
L+ IPKS +RIA+N +FDF+L+ +++ + +N+ R
Sbjct: 258 LVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWR 297
>BT019859-1|AAV38662.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 159 bits (385), Expect = 1e-38
Identities = 83/220 (37%), Positives = 128/220 (58%), Gaps = 13/220 (5%)
Frame = -2
Query: 674 KLWNDKHARXQVVPALQESLKKLGLXYIDLYLIHFPIATKP-------DDS----PDNID 528
KLW H + V A Q++L L L Y+DLYLIH+P KP D+S P + +
Sbjct: 78 KLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTN 137
Query: 527 YLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR--PVINQIEVNPTNTQEPLV 354
L+TW M++ GL ++IG+SNFN Q+ +++ ++ P +NQIE +P TQE L+
Sbjct: 138 ILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLI 197
Query: 353 AHCQSLGIAVMAYSPFGFVVSRGQTGAPPPRSDDPTLTALANKYRKSVGQILLRYLIDRG 174
+CQS GI V AYSP G P +DP + A+A K+ K+ Q+L+R+ + R
Sbjct: 198 QYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRN 257
Query: 173 LIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKKHR 54
L+ IPKS +RIA+N +FDF+L+ +++ + +N+ R
Sbjct: 258 LVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWR 297
>BC010391-1|AAH10391.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 159 bits (385), Expect = 1e-38
Identities = 83/220 (37%), Positives = 128/220 (58%), Gaps = 13/220 (5%)
Frame = -2
Query: 674 KLWNDKHARXQVVPALQESLKKLGLXYIDLYLIHFPIATKP-------DDS----PDNID 528
KLW H + V A Q++L L L Y+DLYLIH+P KP D+S P + +
Sbjct: 78 KLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTN 137
Query: 527 YLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR--PVINQIEVNPTNTQEPLV 354
L+TW M++ GL ++IG+SNFN Q+ +++ ++ P +NQIE +P TQE L+
Sbjct: 138 ILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLI 197
Query: 353 AHCQSLGIAVMAYSPFGFVVSRGQTGAPPPRSDDPTLTALANKYRKSVGQILLRYLIDRG 174
+CQS GI V AYSP G P +DP + A+A K+ K+ Q+L+R+ + R
Sbjct: 198 QYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRN 257
Query: 173 LIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKKHR 54
L+ IPKS +RIA+N +FDF+L+ +++ + +N+ R
Sbjct: 258 LVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWR 297
>BC000260-1|AAH00260.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 159 bits (385), Expect = 1e-38
Identities = 83/220 (37%), Positives = 128/220 (58%), Gaps = 13/220 (5%)
Frame = -2
Query: 674 KLWNDKHARXQVVPALQESLKKLGLXYIDLYLIHFPIATKP-------DDS----PDNID 528
KLW H + V A Q++L L L Y+DLYLIH+P KP D+S P + +
Sbjct: 78 KLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTN 137
Query: 527 YLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR--PVINQIEVNPTNTQEPLV 354
L+TW M++ GL ++IG+SNFN Q+ +++ ++ P +NQIE +P TQE L+
Sbjct: 138 ILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLI 197
Query: 353 AHCQSLGIAVMAYSPFGFVVSRGQTGAPPPRSDDPTLTALANKYRKSVGQILLRYLIDRG 174
+CQS GI V AYSP G P +DP + A+A K+ K+ Q+L+R+ + R
Sbjct: 198 QYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRN 257
Query: 173 LIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKKHR 54
L+ IPKS +RIA+N +FDF+L+ +++ + +N+ R
Sbjct: 258 LVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWR 297
>AF328729-1|AAN09721.1| 316|Homo sapiens CTCL tumor antigen
HD-CL-07 protein.
Length = 316
Score = 159 bits (385), Expect = 1e-38
Identities = 83/220 (37%), Positives = 128/220 (58%), Gaps = 13/220 (5%)
Frame = -2
Query: 674 KLWNDKHARXQVVPALQESLKKLGLXYIDLYLIHFPIATKP-------DDS----PDNID 528
KLW H + V A Q++L L L Y+DLYLIH+P KP D+S P + +
Sbjct: 78 KLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTN 137
Query: 527 YLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR--PVINQIEVNPTNTQEPLV 354
L+TW M++ GL ++IG+SNFN Q+ +++ ++ P +NQIE +P TQE L+
Sbjct: 138 ILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLI 197
Query: 353 AHCQSLGIAVMAYSPFGFVVSRGQTGAPPPRSDDPTLTALANKYRKSVGQILLRYLIDRG 174
+CQS GI V AYSP G P +DP + A+A K+ K+ Q+L+R+ + R
Sbjct: 198 QYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRN 257
Query: 173 LIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKKHR 54
L+ IPKS +RIA+N +FDF+L+ +++ + +N+ R
Sbjct: 258 LVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWR 297
>AF032455-1|AAB88851.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 159 bits (385), Expect = 1e-38
Identities = 83/220 (37%), Positives = 128/220 (58%), Gaps = 13/220 (5%)
Frame = -2
Query: 674 KLWNDKHARXQVVPALQESLKKLGLXYIDLYLIHFPIATKP-------DDS----PDNID 528
KLW H + V A Q++L L L Y+DLYLIH+P KP D+S P + +
Sbjct: 78 KLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTN 137
Query: 527 YLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR--PVINQIEVNPTNTQEPLV 354
L+TW M++ GL ++IG+SNFN Q+ +++ ++ P +NQIE +P TQE L+
Sbjct: 138 ILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLI 197
Query: 353 AHCQSLGIAVMAYSPFGFVVSRGQTGAPPPRSDDPTLTALANKYRKSVGQILLRYLIDRG 174
+CQS GI V AYSP G P +DP + A+A K+ K+ Q+L+R+ + R
Sbjct: 198 QYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRN 257
Query: 173 LIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKKHR 54
L+ IPKS +RIA+N +FDF+L+ +++ + +N+ R
Sbjct: 258 LVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWR 297
>S68288-1|AAD14011.1| 323|Homo sapiens chlordecone reductase
homolog protein.
Length = 323
Score = 158 bits (384), Expect = 1e-38
Identities = 89/235 (37%), Positives = 134/235 (57%), Gaps = 14/235 (5%)
Frame = -2
Query: 674 KLWNDKHARXQVVPALQESLKKLGLXYIDLYLIHFPIATKPDD--SP---------DNID 528
KLW+ H V PAL+ SLKK L Y+DLYLIH P++ KP + SP D +D
Sbjct: 84 KLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEELSPTDENGKVIFDIVD 143
Query: 527 YLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR--PVINQIEVNPTNTQEPLV 354
TW+ M+ + GLA+SIGVSNFN Q+ +++ ++ PV NQ+E +P + L+
Sbjct: 144 LCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEIILNKPGLKYKPVCNQVECHPYFNRSKLL 203
Query: 353 AHCQSLGIAVMAYSPFGFVVSRGQTGAPPP-RSDDPTLTALANKYRKSVGQILLRYLIDR 177
C+S I ++AYS G + P +DP L ALA K++++ I LRY + R
Sbjct: 204 DFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQR 263
Query: 176 GLIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKKHRGIDISDWKDDPNEP 12
G++ + KS N+QRI QN+ +F+FQLT E++ AI+ ++ + + PN P
Sbjct: 264 GVVVLAKSYNEQRIRQNVQVFEFQLTAEDMKAIDGLDRNLHYFNSDSFASHPNYP 318
>L43839-1|AAB41916.1| 323|Homo sapiens 3-alpha-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 158 bits (384), Expect = 1e-38
Identities = 89/235 (37%), Positives = 134/235 (57%), Gaps = 14/235 (5%)
Frame = -2
Query: 674 KLWNDKHARXQVVPALQESLKKLGLXYIDLYLIHFPIATKPDD--SP---------DNID 528
KLW+ H V PAL+ SLKK L Y+DLYLIH P++ KP + SP D +D
Sbjct: 84 KLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEELSPTDENGKVIFDIVD 143
Query: 527 YLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR--PVINQIEVNPTNTQEPLV 354
TW+ M+ + GLA+SIGVSNFN Q+ +++ ++ PV NQ+E +P + L+
Sbjct: 144 LCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEIILNKPGLKYKPVCNQVECHPYFNRSKLL 203
Query: 353 AHCQSLGIAVMAYSPFGFVVSRGQTGAPPP-RSDDPTLTALANKYRKSVGQILLRYLIDR 177
C+S I ++AYS G + P +DP L ALA K++++ I LRY + R
Sbjct: 204 DFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQR 263
Query: 176 GLIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKKHRGIDISDWKDDPNEP 12
G++ + KS N+QRI QN+ +F+FQLT E++ AI+ ++ + + PN P
Sbjct: 264 GVVVLAKSYNEQRIRQNVQVFEFQLTAEDMKAIDGLDRNLHYFNSDSFASHPNYP 318
>U37100-1|AAC17469.1| 316|Homo sapiens aldose reductase-like
peptide protein.
Length = 316
Score = 153 bits (371), Expect = 5e-37
Identities = 85/224 (37%), Positives = 127/224 (56%), Gaps = 13/224 (5%)
Frame = -2
Query: 674 KLWNDKHARXQVVPALQESLKKLGLXYIDLYLIHFPIATK------PDDSPDNI-----D 528
KLW R V A +++LK L L Y+D+YLIH+P K P D N
Sbjct: 78 KLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFPKDDKGNAIGGKAT 137
Query: 527 YLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR--PVINQIEVNPTNTQEPLV 354
+L+ W+ M++ GL +++GVSNF+ QI +L++ ++ PV NQ+E +P TQE L+
Sbjct: 138 FLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLTQEKLI 197
Query: 353 AHCQSLGIAVMAYSPFGFVVSRGQTGAPPPRSDDPTLTALANKYRKSVGQILLRYLIDRG 174
+C S GI V AYSP G P +DP + +A K++K+ Q+L+R+ I R
Sbjct: 198 QYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAKHKKTAAQVLIRFHIQRN 257
Query: 173 LIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKKHRGIDI 42
+I IPKS RI +NI +FDF+L+ EE+A I FN+ R ++
Sbjct: 258 VIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRACNV 301
>CR541801-1|CAG46600.1| 316|Homo sapiens AKR1B10 protein.
Length = 316
Score = 153 bits (371), Expect = 5e-37
Identities = 85/224 (37%), Positives = 127/224 (56%), Gaps = 13/224 (5%)
Frame = -2
Query: 674 KLWNDKHARXQVVPALQESLKKLGLXYIDLYLIHFPIATK------PDDSPDNI-----D 528
KLW R V A +++LK L L Y+D+YLIH+P K P D N
Sbjct: 78 KLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFPKDDKGNAIGGKAT 137
Query: 527 YLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR--PVINQIEVNPTNTQEPLV 354
+L+ W+ M++ GL +++GVSNF+ QI +L++ ++ PV NQ+E +P TQE L+
Sbjct: 138 FLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLTQEKLI 197
Query: 353 AHCQSLGIAVMAYSPFGFVVSRGQTGAPPPRSDDPTLTALANKYRKSVGQILLRYLIDRG 174
+C S GI V AYSP G P +DP + +A K++K+ Q+L+R+ I R
Sbjct: 198 QYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAKHKKTAAQVLIRFHIQRN 257
Query: 173 LIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKKHRGIDI 42
+I IPKS RI +NI +FDF+L+ EE+A I FN+ R ++
Sbjct: 258 VIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRACNV 301
>BT006794-1|AAP35440.1| 316|Homo sapiens aldo-keto reductase family
1, member B10 (aldose reductase) protein.
Length = 316
Score = 153 bits (371), Expect = 5e-37
Identities = 85/224 (37%), Positives = 127/224 (56%), Gaps = 13/224 (5%)
Frame = -2
Query: 674 KLWNDKHARXQVVPALQESLKKLGLXYIDLYLIHFPIATK------PDDSPDNI-----D 528
KLW R V A +++LK L L Y+D+YLIH+P K P D N
Sbjct: 78 KLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFPKDDKGNAIGGKAT 137
Query: 527 YLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR--PVINQIEVNPTNTQEPLV 354
+L+ W+ M++ GL +++GVSNF+ QI +L++ ++ PV NQ+E +P TQE L+
Sbjct: 138 FLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLTQEKLI 197
Query: 353 AHCQSLGIAVMAYSPFGFVVSRGQTGAPPPRSDDPTLTALANKYRKSVGQILLRYLIDRG 174
+C S GI V AYSP G P +DP + +A K++K+ Q+L+R+ I R
Sbjct: 198 QYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAKHKKTAAQVLIRFHIQRN 257
Query: 173 LIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKKHRGIDI 42
+I IPKS RI +NI +FDF+L+ EE+A I FN+ R ++
Sbjct: 258 VIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRACNV 301
>BC008837-1|AAH08837.1| 316|Homo sapiens aldo-keto reductase family
1, member B10 (aldose reductase) protein.
Length = 316
Score = 153 bits (371), Expect = 5e-37
Identities = 85/224 (37%), Positives = 127/224 (56%), Gaps = 13/224 (5%)
Frame = -2
Query: 674 KLWNDKHARXQVVPALQESLKKLGLXYIDLYLIHFPIATK------PDDSPDNI-----D 528
KLW R V A +++LK L L Y+D+YLIH+P K P D N
Sbjct: 78 KLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFPKDDKGNAIGGKAT 137
Query: 527 YLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR--PVINQIEVNPTNTQEPLV 354
+L+ W+ M++ GL +++GVSNF+ QI +L++ ++ PV NQ+E +P TQE L+
Sbjct: 138 FLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLTQEKLI 197
Query: 353 AHCQSLGIAVMAYSPFGFVVSRGQTGAPPPRSDDPTLTALANKYRKSVGQILLRYLIDRG 174
+C S GI V AYSP G P +DP + +A K++K+ Q+L+R+ I R
Sbjct: 198 QYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAKHKKTAAQVLIRFHIQRN 257
Query: 173 LIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKKHRGIDI 42
+I IPKS RI +NI +FDF+L+ EE+A I FN+ R ++
Sbjct: 258 VIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRACNV 301
>BC005387-1|AAH05387.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 153 bits (371), Expect = 5e-37
Identities = 82/220 (37%), Positives = 127/220 (57%), Gaps = 13/220 (5%)
Frame = -2
Query: 674 KLWNDKHARXQVVPALQESLKKLGLXYIDLYLIHFPIATKP-------DDS----PDNID 528
KLW H + V A Q++L L L Y+DLYLIH+P KP D+S P + +
Sbjct: 78 KLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTN 137
Query: 527 YLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR--PVINQIEVNPTNTQEPLV 354
L+T M++ GL ++IG+SNFN Q+ +++ ++ P +NQIE +P TQE L+
Sbjct: 138 ILDTRAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLI 197
Query: 353 AHCQSLGIAVMAYSPFGFVVSRGQTGAPPPRSDDPTLTALANKYRKSVGQILLRYLIDRG 174
+CQS GI V AYSP G P +DP + A+A K+ K+ Q+L+R+ + R
Sbjct: 198 QYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRN 257
Query: 173 LIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKKHR 54
L+ IPKS +RIA+N +FDF+L+ +++ + +N+ R
Sbjct: 258 LVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWR 297
>AF052577-1|AAC36465.1| 316|Homo sapiens aldo-keto reductase
protein.
Length = 316
Score = 153 bits (371), Expect = 5e-37
Identities = 85/224 (37%), Positives = 127/224 (56%), Gaps = 13/224 (5%)
Frame = -2
Query: 674 KLWNDKHARXQVVPALQESLKKLGLXYIDLYLIHFPIATK------PDDSPDNI-----D 528
KLW R V A +++LK L L Y+D+YLIH+P K P D N
Sbjct: 78 KLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFPKDDKGNAIGGKAT 137
Query: 527 YLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR--PVINQIEVNPTNTQEPLV 354
+L+ W+ M++ GL +++GVSNF+ QI +L++ ++ PV NQ+E +P TQE L+
Sbjct: 138 FLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLTQEKLI 197
Query: 353 AHCQSLGIAVMAYSPFGFVVSRGQTGAPPPRSDDPTLTALANKYRKSVGQILLRYLIDRG 174
+C S GI V AYSP G P +DP + +A K++K+ Q+L+R+ I R
Sbjct: 198 QYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAKHKKTAAQVLIRFHIQRN 257
Query: 173 LIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKKHRGIDI 42
+I IPKS RI +NI +FDF+L+ EE+A I FN+ R ++
Sbjct: 258 VIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRACNV 301
>AF524864-1|AAO13380.1| 316|Homo sapiens aldo-ketoreductase
protein.
Length = 316
Score = 150 bits (363), Expect = 5e-36
Identities = 84/224 (37%), Positives = 126/224 (56%), Gaps = 13/224 (5%)
Frame = -2
Query: 674 KLWNDKHARXQVVPALQESLKKLGLXYIDLYLIHFPIATK------PDDSPDNI-----D 528
KLW R V A +++LK L Y+D+YLIH+P K P D N
Sbjct: 78 KLWPTFFERPLVRKAFEKTLKDPKLSYLDVYLIHWPQGFKSGDDLFPKDDKGNAIGGKAT 137
Query: 527 YLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR--PVINQIEVNPTNTQEPLV 354
+L+ W+ M++ GL +++GVSNF+ QI +L++ ++ PV NQ+E +P TQE L+
Sbjct: 138 FLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLTQEKLI 197
Query: 353 AHCQSLGIAVMAYSPFGFVVSRGQTGAPPPRSDDPTLTALANKYRKSVGQILLRYLIDRG 174
+C S GI V AYSP G P +DP + +A K++K+ Q+L+R+ I R
Sbjct: 198 QYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAKHKKTAAQVLIRFHIQRN 257
Query: 173 LIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKKHRGIDI 42
+I IPKS RI +NI +FDF+L+ EE+A I FN+ R ++
Sbjct: 258 VIVIPKSVTPARIVENIQVFDFKLSDEEMAIILSFNRNWRACNV 301
>AL713867-3|CAI16410.1| 247|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 247
Score = 140 bits (340), Expect = 3e-33
Identities = 77/198 (38%), Positives = 112/198 (56%), Gaps = 14/198 (7%)
Frame = -2
Query: 674 KLWNDKHARXQVVPALQESLKKLGLXYIDLYLIHFPIATKPDDSP-----------DNID 528
KLW + H V PAL+ SLK L L Y+DLYLIHFP++ KP + D +D
Sbjct: 50 KLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVD 109
Query: 527 YLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI--RPVINQIEVNPTNTQEPLV 354
TW+ ++ + GLA+SIGVSNFN Q+ +++ + +PV NQ+E +P Q L+
Sbjct: 110 LCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLL 169
Query: 353 AHCQSLGIAVMAYSPFGFVVSRGQTGA-PPPRSDDPTLTALANKYRKSVGQILLRYLIDR 177
C+S I ++AYS G P +DP L ALA K++++ I LRY + R
Sbjct: 170 DFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQR 229
Query: 176 GLIPIPKSTNKQRIAQNI 123
G++ + KS N+QRI QN+
Sbjct: 230 GVVVLAKSYNEQRIRQNV 247
>AF263242-1|AAK58523.1| 320|Homo sapiens aldo-keto reductase
loopADR protein.
Length = 320
Score = 116 bits (278), Expect(2) = 3e-33
Identities = 64/165 (38%), Positives = 96/165 (58%), Gaps = 2/165 (1%)
Frame = -2
Query: 542 PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR--PVINQIEVNPTNT 369
P + D+L+TW+ M+D GL ++IGVSNFN Q+ RL++ +R P+ NQIE +P T
Sbjct: 143 PSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIECHPYLT 202
Query: 368 QEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPPRSDDPTLTALANKYRKSVGQILLRY 189
Q+ L++ CQS ++V AY P G G D+P + +A ++ KS QIL+R+
Sbjct: 203 QKNLISFCQSRDVSVTAYRPLG-----GSCEGVD-LIDNPVIKRIAKEHGKSPAQILIRF 256
Query: 188 LIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKKHR 54
I R +I IP S I +NI +FDF+LT ++ I N+ R
Sbjct: 257 QIQRNVIVIPGSITPSHIKENIQVFDFELTQHDMDNILSLNRNLR 301
Score = 46.0 bits (104), Expect(2) = 3e-33
Identities = 21/41 (51%), Positives = 27/41 (65%)
Frame = -2
Query: 674 KLWNDKHARXQVVPALQESLKKLGLXYIDLYLIHFPIATKP 552
KLW H + V A ++SLK L L Y+DLYLIH+P+ KP
Sbjct: 69 KLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKP 109
>BC002862-1|AAH02862.1| 307|Homo sapiens AKR1CL2 protein protein.
Length = 307
Score = 116 bits (278), Expect(2) = 3e-33
Identities = 64/165 (38%), Positives = 96/165 (58%), Gaps = 2/165 (1%)
Frame = -2
Query: 542 PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR--PVINQIEVNPTNT 369
P + D+L+TW+ M+D GL ++IGVSNFN Q+ RL++ +R P+ NQIE +P T
Sbjct: 143 PSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIECHPYLT 202
Query: 368 QEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPPRSDDPTLTALANKYRKSVGQILLRY 189
Q+ L++ CQS ++V AY P G G D+P + +A ++ KS QIL+R+
Sbjct: 203 QKNLISFCQSRDVSVTAYRPLG-----GSCEGVD-LIDNPVIKRIAKEHGKSPAQILIRF 256
Query: 188 LIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKKHR 54
I R +I IP S I +NI +FDF+LT ++ I N+ R
Sbjct: 257 QIQRNVIVIPGSITPSHIKENIQVFDFELTQHDMDNILSLNRNLR 301
Score = 46.0 bits (104), Expect(2) = 3e-33
Identities = 21/41 (51%), Positives = 27/41 (65%)
Frame = -2
Query: 674 KLWNDKHARXQVVPALQESLKKLGLXYIDLYLIHFPIATKP 552
KLW H + V A ++SLK L L Y+DLYLIH+P+ KP
Sbjct: 69 KLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKP 109
>AB055603-1|BAC54568.1| 307|Homo sapiens aldo-keto reductase
related protein 4 protein.
Length = 307
Score = 116 bits (278), Expect(2) = 3e-33
Identities = 64/165 (38%), Positives = 96/165 (58%), Gaps = 2/165 (1%)
Frame = -2
Query: 542 PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR--PVINQIEVNPTNT 369
P + D+L+TW+ M+D GL ++IGVSNFN Q+ RL++ +R P+ NQIE +P T
Sbjct: 143 PSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIECHPYLT 202
Query: 368 QEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGAPPPRSDDPTLTALANKYRKSVGQILLRY 189
Q+ L++ CQS ++V AY P G G D+P + +A ++ KS QIL+R+
Sbjct: 203 QKNLISFCQSRDVSVTAYRPLG-----GSCEGVD-LIDNPVIKRIAKEHGKSPAQILIRF 256
Query: 188 LIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKKHR 54
I R +I IP S I +NI +FDF+LT ++ I N+ R
Sbjct: 257 QIQRNVIVIPGSITPSHIKENIQVFDFELTQHDMDNILSLNRNLR 301
Score = 46.0 bits (104), Expect(2) = 3e-33
Identities = 21/41 (51%), Positives = 27/41 (65%)
Frame = -2
Query: 674 KLWNDKHARXQVVPALQESLKKLGLXYIDLYLIHFPIATKP 552
KLW H + V A ++SLK L L Y+DLYLIH+P+ KP
Sbjct: 69 KLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKP 109
>AB209796-1|BAD93033.1| 260|Homo sapiens aldo-keto reductase family
1, member B1 variant protein.
Length = 260
Score = 116 bits (280), Expect = 6e-26
Identities = 65/171 (38%), Positives = 95/171 (55%), Gaps = 13/171 (7%)
Frame = -2
Query: 674 KLWNDKHARXQVVPALQESLKKLGLXYIDLYLIHFPIATKP-------DDS----PDNID 528
KLW H + V A Q++L L L Y+DLYLIH+P KP D+S P + +
Sbjct: 75 KLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTN 134
Query: 527 YLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR--PVINQIEVNPTNTQEPLV 354
L+TW M++ GL ++IG+SNFN Q+ +++ ++ P +NQIE +P TQE L+
Sbjct: 135 ILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLI 194
Query: 353 AHCQSLGIAVMAYSPFGFVVSRGQTGAPPPRSDDPTLTALANKYRKSVGQI 201
+CQS GI V AYSP G P +DP + A+A K+ K+ Q+
Sbjct: 195 QYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKTTAQV 245
>AB209017-1|BAD92254.1| 286|Homo sapiens aldo-keto reductase family
1, member C2 variant protein.
Length = 286
Score = 109 bits (263), Expect = 7e-24
Identities = 63/164 (38%), Positives = 88/164 (53%), Gaps = 14/164 (8%)
Frame = -2
Query: 674 KLWNDKHARXQVVPALQESLKKLGLXYIDLYLIHFPIATKPDDSP-----------DNID 528
KLW++ H V PAL+ SLK L L Y+DLYLIHFP++ KP + D +D
Sbjct: 97 KLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVD 156
Query: 527 YLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI--RPVINQIEVNPTNTQEPLV 354
TW+ M+ + GLA+SIGVSNFN + +++ + +PV NQ+E +P Q L+
Sbjct: 157 LCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLL 216
Query: 353 AHCQSLGIAVMAYSPFGFVVSRGQTGA-PPPRSDDPTLTALANK 225
C+S I ++AYS G P +DP L ALA K
Sbjct: 217 DFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKK 260
>AL391427-2|CAI14727.1| 302|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 302
Score = 101 bits (241), Expect = 3e-21
Identities = 66/209 (31%), Positives = 107/209 (51%), Gaps = 2/209 (0%)
Frame = -2
Query: 674 KLWNDKHARXQVVPALQESLKKLGLXYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDA 495
KLW V PAL+ SLKKLG Y+DL++IH P A K + L +DA
Sbjct: 87 KLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFAMKQPGK----ELLP-----KDA 137
Query: 494 RQLGLARSIGVSNFNATQITRLVSNSYIRPVINQI-EVNPTNTQEPLVAHCQSLGIAVMA 318
+ ++ + + ++ +P NQ+ E +P Q L+ C+S I ++A
Sbjct: 138 SGEIILETVELCDTWELELILNKPGLRYKPTCNQVVECHPYLNQSKLLEFCKSKDIVLVA 197
Query: 317 YSPFGFVVSRGQTGAPPPRS-DDPTLTALANKYRKSVGQILLRYLIDRGLIPIPKSTNKQ 141
YS G P ++P L ++A K+ +S GQ+ LRY + RG++ + KS +++
Sbjct: 198 YSALGSQRDPQWVDPDCPHLLEEPILKSIAKKHSRSPGQVALRYQLQRGVVVLAKSFSQE 257
Query: 140 RIAQNIDLFDFQLTFEEVAAINQFNKKHR 54
RI +N +FDF+LT E++ AI+ N+ R
Sbjct: 258 RIKENFQIFDFELTPEDMKAIDGLNRNLR 286
>AL355303-1|CAI14201.1| 302|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 302
Score = 101 bits (241), Expect = 3e-21
Identities = 66/209 (31%), Positives = 107/209 (51%), Gaps = 2/209 (0%)
Frame = -2
Query: 674 KLWNDKHARXQVVPALQESLKKLGLXYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDA 495
KLW V PAL+ SLKKLG Y+DL++IH P A K + L +DA
Sbjct: 87 KLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFAMKQPGK----ELLP-----KDA 137
Query: 494 RQLGLARSIGVSNFNATQITRLVSNSYIRPVINQI-EVNPTNTQEPLVAHCQSLGIAVMA 318
+ ++ + + ++ +P NQ+ E +P Q L+ C+S I ++A
Sbjct: 138 SGEIILETVELCDTWELELILNKPGLRYKPTCNQVVECHPYLNQSKLLEFCKSKDIVLVA 197
Query: 317 YSPFGFVVSRGQTGAPPPRS-DDPTLTALANKYRKSVGQILLRYLIDRGLIPIPKSTNKQ 141
YS G P ++P L ++A K+ +S GQ+ LRY + RG++ + KS +++
Sbjct: 198 YSALGSQRDPQWVDPDCPHLLEEPILKSIAKKHSRSPGQVALRYQLQRGVVVLAKSFSQE 257
Query: 140 RIAQNIDLFDFQLTFEEVAAINQFNKKHR 54
RI +N +FDF+LT E++ AI+ N+ R
Sbjct: 258 RIKENFQIFDFELTPEDMKAIDGLNRNLR 286
>AB040821-1|BAC54566.1| 263|Homo sapiens aldo-keto reductase
related protein 2 protein.
Length = 263
Score = 52.4 bits (120), Expect(2) = 3e-14
Identities = 24/53 (45%), Positives = 36/53 (67%), Gaps = 2/53 (3%)
Frame = -2
Query: 542 PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR--PVINQI 390
P + D+L+TW+ M+D GL ++IGVSNFN Q+ RL++ +R P+ NQI
Sbjct: 143 PSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQI 195
Score = 46.0 bits (104), Expect(2) = 3e-14
Identities = 21/41 (51%), Positives = 27/41 (65%)
Frame = -2
Query: 674 KLWNDKHARXQVVPALQESLKKLGLXYIDLYLIHFPIATKP 552
KLW H + V A ++SLK L L Y+DLYLIH+P+ KP
Sbjct: 69 KLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKP 109
Score = 44.4 bits (100), Expect = 4e-04
Identities = 21/58 (36%), Positives = 33/58 (56%)
Frame = -2
Query: 227 KYRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKKHR 54
+++ QIL+R+ I R +I IP S I +NI +FDF+LT ++ I N+ R
Sbjct: 187 RFKPLTNQILIRFQIQRNVIVIPGSITPSHIKENIQVFDFELTQHDMDNILSLNRNLR 244
>AB040820-1|BAC54565.1| 250|Homo sapiens aldo-keto reductase
related protein 1 protein.
Length = 250
Score = 52.4 bits (120), Expect(2) = 3e-14
Identities = 24/53 (45%), Positives = 36/53 (67%), Gaps = 2/53 (3%)
Frame = -2
Query: 542 PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR--PVINQI 390
P + D+L+TW+ M+D GL ++IGVSNFN Q+ RL++ +R P+ NQI
Sbjct: 143 PSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQI 195
Score = 46.0 bits (104), Expect(2) = 3e-14
Identities = 21/41 (51%), Positives = 27/41 (65%)
Frame = -2
Query: 674 KLWNDKHARXQVVPALQESLKKLGLXYIDLYLIHFPIATKP 552
KLW H + V A ++SLK L L Y+DLYLIH+P+ KP
Sbjct: 69 KLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKP 109
Score = 44.4 bits (100), Expect = 4e-04
Identities = 21/58 (36%), Positives = 33/58 (56%)
Frame = -2
Query: 227 KYRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKKHR 54
+++ QIL+R+ I R +I IP S I +NI +FDF+LT ++ I N+ R
Sbjct: 187 RFKPLTNQILIRFQIQRNVIVIPGSITPSHIKENIQVFDFELTQHDMDNILSLNRNLR 244
>AF044961-1|AAC15671.1| 85|Homo sapiens aldose reductase-related
protein protein.
Length = 85
Score = 65.7 bits (153), Expect = 1e-10
Identities = 29/70 (41%), Positives = 46/70 (65%)
Frame = -2
Query: 251 PTLTALANKYRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQ 72
P + +A K++K+ Q+L+R+ I R +I IPKS RI +NI +FDF+L+ EE+A I
Sbjct: 1 PKIKEIAAKHKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILS 60
Query: 71 FNKKHRGIDI 42
FN+ R ++
Sbjct: 61 FNRNWRACNV 70
>AK058142-1|BAB71682.1| 146|Homo sapiens protein ( Homo sapiens
cDNA FLJ25413 fis, clone TST03402, highly similar to
3-OXO-5-BETA-STEROID 4-DEHYDROGENASE (EC 1.3.99.6). ).
Length = 146
Score = 65.3 bits (152), Expect = 2e-10
Identities = 30/74 (40%), Positives = 45/74 (60%), Gaps = 2/74 (2%)
Frame = -2
Query: 518 TWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR--PVINQIEVNPTNTQEPLVAHC 345
TW+ M+ + GL +S+GVSNFN Q+ +++ ++ PV NQ+E +P TQ L+ C
Sbjct: 28 TWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKPVSNQVECHPYFTQPKLLKFC 87
Query: 344 QSLGIAVMAYSPFG 303
Q I + AYSP G
Sbjct: 88 QQHDIVITAYSPLG 101
>AL355480-2|CAI22458.1| 147|Homo sapiens aldo-keto reductase family
1, member A1 (aldehydela) protein.
Length = 147
Score = 53.6 bits (123), Expect = 6e-07
Identities = 28/68 (41%), Positives = 39/68 (57%), Gaps = 11/68 (16%)
Frame = -2
Query: 674 KLWNDKHARXQVVPALQESLKKLGLXYIDLYLIHFPIATKPDDSP-----------DNID 528
KLWN KH V PAL+++L L L Y+DLYL+H+P A + D+P D+
Sbjct: 80 KLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNADGTICYDSTH 139
Query: 527 YLETWQGM 504
Y ETW+ +
Sbjct: 140 YKETWKAL 147
>AB028065-1|BAA88489.1| 67|Homo sapiens prostaglandin F synthase
protein.
Length = 67
Score = 46.4 bits (105), Expect = 9e-05
Identities = 21/51 (41%), Positives = 32/51 (62%), Gaps = 2/51 (3%)
Frame = -2
Query: 539 DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI--RPVINQ 393
D +D TW+ M+ + GLA+SIGVSNFN Q+ +++ + +PV NQ
Sbjct: 17 DIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQ 67
>AB040822-1|BAC54567.1| 222|Homo sapiens aldo-keto reductase
related protein 3 protein.
Length = 222
Score = 46.0 bits (104), Expect = 1e-04
Identities = 21/41 (51%), Positives = 27/41 (65%)
Frame = -2
Query: 674 KLWNDKHARXQVVPALQESLKKLGLXYIDLYLIHFPIATKP 552
KLW H + V A ++SLK L L Y+DLYLIH+P+ KP
Sbjct: 69 KLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKP 109
Score = 41.5 bits (93), Expect = 0.003
Identities = 20/51 (39%), Positives = 30/51 (58%)
Frame = -2
Query: 206 QILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFEEVAAINQFNKKHR 54
+IL+R+ I R +I IP S I +NI +FDF+LT ++ I N+ R
Sbjct: 153 EILIRFQIQRNVIVIPGSITPSHIKENIQVFDFELTQHDMDNILSLNRNLR 203
>BC101205-1|AAI01206.1| 129|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 129
Score = 44.8 bits (101), Expect = 3e-04
Identities = 21/40 (52%), Positives = 25/40 (62%)
Frame = -2
Query: 674 KLWNDKHARXQVVPALQESLKKLGLXYIDLYLIHFPIATK 555
KLW V PAL+ SLKKLG Y+DL++IH P A K
Sbjct: 87 KLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFAMK 126
>BC101204-1|AAI01205.1| 129|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 129
Score = 44.8 bits (101), Expect = 3e-04
Identities = 21/40 (52%), Positives = 25/40 (62%)
Frame = -2
Query: 674 KLWNDKHARXQVVPALQESLKKLGLXYIDLYLIHFPIATK 555
KLW V PAL+ SLKKLG Y+DL++IH P A K
Sbjct: 87 KLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFAMK 126
>AK131335-1|BAD18494.1| 129|Homo sapiens protein ( Homo sapiens
cDNA FLJ16347 fis, clone TESTI2036288, moderately
similar to PROSTAGLANDIN-F SYNTHASE 1 (EC 1.1.1.188). ).
Length = 129
Score = 44.8 bits (101), Expect = 3e-04
Identities = 21/40 (52%), Positives = 25/40 (62%)
Frame = -2
Query: 674 KLWNDKHARXQVVPALQESLKKLGLXYIDLYLIHFPIATK 555
KLW V PAL+ SLKKLG Y+DL++IH P A K
Sbjct: 87 KLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFAMK 126
>AB037902-1|BAA92887.1| 130|Homo sapiens truncated aldo-keto
reductase protein.
Length = 130
Score = 41.9 bits (94), Expect = 0.002
Identities = 20/44 (45%), Positives = 25/44 (56%)
Frame = -2
Query: 674 KLWNDKHARXQVVPALQESLKKLGLXYIDLYLIHFPIATKPDDS 543
K+W V L+ SLKKL L Y+DLYL HFP+ +P S
Sbjct: 85 KVWGTFSRPELVQRGLEMSLKKLQLSYMDLYLFHFPVPLQPGRS 128
>AB037905-2|BAA92890.1| 45|Homo sapiens truncated aldo-keto
reductase protein.
Length = 45
Score = 39.9 bits (89), Expect = 0.008
Identities = 19/43 (44%), Positives = 24/43 (55%)
Frame = -2
Query: 671 LWNDKHARXQVVPALQESLKKLGLXYIDLYLIHFPIATKPDDS 543
+W V L+ SLKKL L Y+DLYL HFP+ +P S
Sbjct: 1 VWGTFSRPELVQRGLEMSLKKLQLSYMDLYLFHFPVPLQPGRS 43
>Y16675-1|CAA76347.1| 330|Homo sapiens aflatoxin B1-aldehyde
reductase protein.
Length = 330
Score = 38.7 bits (86), Expect = 0.019
Identities = 35/127 (27%), Positives = 57/127 (44%), Gaps = 7/127 (5%)
Frame = -2
Query: 668 WNDKHARXQVVPA-LQESLKKLGLXYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDAR 492
W+ K + V + L+ SLK+L +DL+ +H P P + ET Q
Sbjct: 80 WDGKSLKPDSVRSQLETSLKRLQCPQVDLFYLHAPDHGTPVE--------ETLHACQRLH 131
Query: 491 QLGLARSIGVSNFNATQITRLV----SNSYIRPVINQIEVNPTNTQ-EPLVAHC-QSLGI 330
Q G +G+SN+ + ++ + SN +I P + Q N T Q E + C + G+
Sbjct: 132 QEGKFVELGLSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGL 191
Query: 329 AVMAYSP 309
AY+P
Sbjct: 192 RFYAYNP 198
>BT007347-1|AAP36011.1| 330|Homo sapiens aldo-keto reductase family
7, member A2 (aflatoxin aldehyde reductase) protein.
Length = 330
Score = 38.7 bits (86), Expect = 0.019
Identities = 35/127 (27%), Positives = 57/127 (44%), Gaps = 7/127 (5%)
Frame = -2
Query: 668 WNDKHARXQVVPA-LQESLKKLGLXYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDAR 492
W+ K + V + L+ SLK+L +DL+ +H P P + ET Q
Sbjct: 80 WDGKSLKPDSVRSQLETSLKRLQCPQVDLFYLHAPDHGTPVE--------ETLHACQRLH 131
Query: 491 QLGLARSIGVSNFNATQITRLV----SNSYIRPVINQIEVNPTNTQ-EPLVAHC-QSLGI 330
Q G +G+SN+ + ++ + SN +I P + Q N T Q E + C + G+
Sbjct: 132 QEGKFVELGLSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGL 191
Query: 329 AVMAYSP 309
AY+P
Sbjct: 192 RFYAYNP 198
>BC013996-1|AAH13996.1| 330|Homo sapiens AKR7A2 protein protein.
Length = 330
Score = 38.7 bits (86), Expect = 0.019
Identities = 35/127 (27%), Positives = 57/127 (44%), Gaps = 7/127 (5%)
Frame = -2
Query: 668 WNDKHARXQVVPA-LQESLKKLGLXYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDAR 492
W+ K + V + L+ SLK+L +DL+ +H P P + ET Q
Sbjct: 80 WDGKSLKPDSVRSQLETSLKRLQCPQVDLFYLHAPDHGTPVE--------ETLHACQRLH 131
Query: 491 QLGLARSIGVSNFNATQITRLV----SNSYIRPVINQIEVNPTNTQ-EPLVAHC-QSLGI 330
Q G +G+SN+ + ++ + SN +I P + Q N T Q E + C + G+
Sbjct: 132 QEGKFVELGLSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGL 191
Query: 329 AVMAYSP 309
AY+P
Sbjct: 192 RFYAYNP 198
>BC012171-1|AAH12171.1| 330|Homo sapiens AKR7A2 protein protein.
Length = 330
Score = 38.7 bits (86), Expect = 0.019
Identities = 35/127 (27%), Positives = 57/127 (44%), Gaps = 7/127 (5%)
Frame = -2
Query: 668 WNDKHARXQVVPA-LQESLKKLGLXYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDAR 492
W+ K + V + L+ SLK+L +DL+ +H P P + ET Q
Sbjct: 80 WDGKSLKPDSVRSQLETSLKRLQCPQVDLFYLHAPDHGTPVE--------ETLHACQRLH 131
Query: 491 QLGLARSIGVSNFNATQITRLV----SNSYIRPVINQIEVNPTNTQ-EPLVAHC-QSLGI 330
Q G +G+SN+ + ++ + SN +I P + Q N T Q E + C + G+
Sbjct: 132 QEGKFVELGLSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGL 191
Query: 329 AVMAYSP 309
AY+P
Sbjct: 192 RFYAYNP 198
>BC011586-1|AAH11586.1| 330|Homo sapiens AKR7A2 protein protein.
Length = 330
Score = 38.7 bits (86), Expect = 0.019
Identities = 35/127 (27%), Positives = 57/127 (44%), Gaps = 7/127 (5%)
Frame = -2
Query: 668 WNDKHARXQVVPA-LQESLKKLGLXYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDAR 492
W+ K + V + L+ SLK+L +DL+ +H P P + ET Q
Sbjct: 80 WDGKSLKPDSVRSQLETSLKRLQCPQVDLFYLHAPDHGTPVE--------ETLHACQRLH 131
Query: 491 QLGLARSIGVSNFNATQITRLV----SNSYIRPVINQIEVNPTNTQ-EPLVAHC-QSLGI 330
Q G +G+SN+ + ++ + SN +I P + Q N T Q E + C + G+
Sbjct: 132 QEGKFVELGLSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGL 191
Query: 329 AVMAYSP 309
AY+P
Sbjct: 192 RFYAYNP 198
>BC010852-1|AAH10852.1| 330|Homo sapiens AKR7A2 protein protein.
Length = 330
Score = 38.7 bits (86), Expect = 0.019
Identities = 35/127 (27%), Positives = 57/127 (44%), Gaps = 7/127 (5%)
Frame = -2
Query: 668 WNDKHARXQVVPA-LQESLKKLGLXYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDAR 492
W+ K + V + L+ SLK+L +DL+ +H P P + ET Q
Sbjct: 80 WDGKSLKPDSVRSQLETSLKRLQCPQVDLFYLHAPDHGTPVE--------ETLHACQRLH 131
Query: 491 QLGLARSIGVSNFNATQITRLV----SNSYIRPVINQIEVNPTNTQ-EPLVAHC-QSLGI 330
Q G +G+SN+ + ++ + SN +I P + Q N T Q E + C + G+
Sbjct: 132 QEGKFVELGLSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGL 191
Query: 329 AVMAYSP 309
AY+P
Sbjct: 192 RFYAYNP 198
>BC007352-1|AAH07352.2| 358|Homo sapiens AKR7A2 protein protein.
Length = 358
Score = 38.7 bits (86), Expect = 0.019
Identities = 35/127 (27%), Positives = 57/127 (44%), Gaps = 7/127 (5%)
Frame = -2
Query: 668 WNDKHARXQVVPA-LQESLKKLGLXYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDAR 492
W+ K + V + L+ SLK+L +DL+ +H P P + ET Q
Sbjct: 108 WDGKSLKPDSVRSQLETSLKRLQCPQVDLFYLHAPDHGTPVE--------ETLHACQRLH 159
Query: 491 QLGLARSIGVSNFNATQITRLV----SNSYIRPVINQIEVNPTNTQ-EPLVAHC-QSLGI 330
Q G +G+SN+ + ++ + SN +I P + Q N T Q E + C + G+
Sbjct: 160 QEGKFVELGLSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGL 219
Query: 329 AVMAYSP 309
AY+P
Sbjct: 220 RFYAYNP 226
>BC004111-1|AAH04111.3| 330|Homo sapiens AKR7A2 protein protein.
Length = 330
Score = 38.7 bits (86), Expect = 0.019
Identities = 35/127 (27%), Positives = 57/127 (44%), Gaps = 7/127 (5%)
Frame = -2
Query: 668 WNDKHARXQVVPA-LQESLKKLGLXYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDAR 492
W+ K + V + L+ SLK+L +DL+ +H P P + ET Q
Sbjct: 80 WDGKSLKPDSVRSQLETSLKRLQCPQVDLFYLHAPDHGTPVE--------ETLHACQRLH 131
Query: 491 QLGLARSIGVSNFNATQITRLV----SNSYIRPVINQIEVNPTNTQ-EPLVAHC-QSLGI 330
Q G +G+SN+ + ++ + SN +I P + Q N T Q E + C + G+
Sbjct: 132 QEGKFVELGLSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGL 191
Query: 329 AVMAYSP 309
AY+P
Sbjct: 192 RFYAYNP 198
>AL035413-8|CAB72321.1| 330|Homo sapiens aldo-keto reductase family
7, member A2 (aflatoxin aldehyde reductase) protein.
Length = 330
Score = 38.7 bits (86), Expect = 0.019
Identities = 35/127 (27%), Positives = 57/127 (44%), Gaps = 7/127 (5%)
Frame = -2
Query: 668 WNDKHARXQVVPA-LQESLKKLGLXYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDAR 492
W+ K + V + L+ SLK+L +DL+ +H P P + ET Q
Sbjct: 80 WDGKSLKPDSVRSQLETSLKRLQCPQVDLFYLHAPDHGTPVE--------ETLHACQRLH 131
Query: 491 QLGLARSIGVSNFNATQITRLV----SNSYIRPVINQIEVNPTNTQ-EPLVAHC-QSLGI 330
Q G +G+SN+ + ++ + SN +I P + Q N T Q E + C + G+
Sbjct: 132 QEGKFVELGLSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGL 191
Query: 329 AVMAYSP 309
AY+P
Sbjct: 192 RFYAYNP 198
>AF026947-1|AAC52104.1| 330|Homo sapiens aflatoxin aldehyde
reductase AFAR protein.
Length = 330
Score = 38.7 bits (86), Expect = 0.019
Identities = 35/127 (27%), Positives = 57/127 (44%), Gaps = 7/127 (5%)
Frame = -2
Query: 668 WNDKHARXQVVPA-LQESLKKLGLXYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDAR 492
W+ K + V + L+ SLK+L +DL+ +H P P + ET Q
Sbjct: 80 WDGKSLKPDSVRSQLETSLKRLQCPQVDLFYLHTPDHGTPVE--------ETLHACQRLH 131
Query: 491 QLGLARSIGVSNFNATQITRLV----SNSYIRPVINQIEVNPTNTQ-EPLVAHC-QSLGI 330
Q G +G+SN+ + ++ + SN +I P + Q N T Q E + C + G+
Sbjct: 132 QEGKFVELGLSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGL 191
Query: 329 AVMAYSP 309
AY+P
Sbjct: 192 RFYAYNP 198
>AJ278012-1|CAC79668.1| 259|Homo sapiens aflatoxin B1 aldehyde
reductase 3 protein.
Length = 259
Score = 37.9 bits (84), Expect = 0.033
Identities = 30/113 (26%), Positives = 51/113 (45%), Gaps = 6/113 (5%)
Frame = -2
Query: 629 LQESLKKLGLXYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFN 450
L+ SLK+L +DL+ +H P + P + ET + Q G +G+SN+
Sbjct: 23 LETSLKRLQCPUVDLFYLHAPDHSAPVE--------ETLRACHQLHQEGKFVELGLSNYA 74
Query: 449 ATQITRLV----SNSYIRPVINQIEVNPTNTQ--EPLVAHCQSLGIAVMAYSP 309
A ++ + SN +I P + Q + T Q L + + G+ AY+P
Sbjct: 75 AWEVAEICTLCKSNGWILPTVYQGMYSATTRQVETELFPYLRHFGLRFYAYNP 127
>BC042420-1|AAH42420.2| 331|Homo sapiens aldo-keto reductase family
7, member A3 (aflatoxin aldehyde reductase) protein.
Length = 331
Score = 35.9 bits (79), Expect = 0.13
Identities = 30/113 (26%), Positives = 51/113 (45%), Gaps = 6/113 (5%)
Frame = -2
Query: 629 LQESLKKLGLXYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFN 450
L+ SLK+L +DL+ +H P + P + ET + Q G +G+SN+
Sbjct: 95 LETSLKRLQCPRVDLFYLHMPDHSTPVE--------ETLRACHQLHQEGKFMELGLSNYA 146
Query: 449 ATQITRLV----SNSYIRPVINQIEVNPTNTQ-EPLVAHC-QSLGIAVMAYSP 309
A ++ + SN +I P + Q N Q E + C + G+ A++P
Sbjct: 147 AWEVAEICTLCKSNGWILPTVYQGMYNAITRQVETELFPCLRHFGLRFYAFNP 199
>BC031562-1|AAH31562.1| 331|Homo sapiens aldo-keto reductase family
7, member A3 (aflatoxin aldehyde reductase) protein.
Length = 331
Score = 35.9 bits (79), Expect = 0.13
Identities = 30/113 (26%), Positives = 51/113 (45%), Gaps = 6/113 (5%)
Frame = -2
Query: 629 LQESLKKLGLXYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFN 450
L+ SLK+L +DL+ +H P + P + ET + Q G +G+SN+
Sbjct: 95 LETSLKRLQCPRVDLFYLHMPDHSTPVE--------ETLRACHQLHQEGKFMELGLSNYA 146
Query: 449 ATQITRLV----SNSYIRPVINQIEVNPTNTQ-EPLVAHC-QSLGIAVMAYSP 309
A ++ + SN +I P + Q N Q E + C + G+ A++P
Sbjct: 147 AWEVAEICTLCKSNGWILPTVYQGMYNAITRQVETELFPCLRHFGLRFYAFNP 199
>AJ271799-1|CAC81076.1| 331|Homo sapiens aflatoxin B1 aldehyde
reductase 2 protein.
Length = 331
Score = 35.9 bits (79), Expect = 0.13
Identities = 30/113 (26%), Positives = 51/113 (45%), Gaps = 6/113 (5%)
Frame = -2
Query: 629 LQESLKKLGLXYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFN 450
L+ SLK+L +DL+ +H P + P + ET + Q G +G+SN+
Sbjct: 95 LETSLKRLQCPRVDLFYLHMPDHSTPVE--------ETLRACHQLHQEGKFMELGLSNYA 146
Query: 449 ATQITRLV----SNSYIRPVINQIEVNPTNTQ-EPLVAHC-QSLGIAVMAYSP 309
A ++ + SN +I P + Q N Q E + C + G+ A++P
Sbjct: 147 AWEVAEICTLCKSNGWILPTVYQGMYNAITRQVETELFPCLRHFGLRFYAFNP 199
>AF040639-1|AAD02195.1| 331|Homo sapiens aflatoxin B1-aldehyde
reductase protein.
Length = 331
Score = 35.9 bits (79), Expect = 0.13
Identities = 30/113 (26%), Positives = 51/113 (45%), Gaps = 6/113 (5%)
Frame = -2
Query: 629 LQESLKKLGLXYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFN 450
L+ SLK+L +DL+ +H P + P + ET + Q G +G+SN+
Sbjct: 95 LETSLKRLQCPRVDLFYLHMPDHSTPVE--------ETLRACHQLHQEGKFMELGLSNYA 146
Query: 449 ATQITRLV----SNSYIRPVINQIEVNPTNTQ-EPLVAHC-QSLGIAVMAYSP 309
A ++ + SN +I P + Q N Q E + C + G+ A++P
Sbjct: 147 AWEVAEICTLCKSNGWILPTVYQGMYNAITRQVETELFPCLRHFGLRFYAFNP 199
>AK025747-1|BAB15231.1| 171|Homo sapiens protein ( Homo sapiens
cDNA: FLJ22094 fis, clone HEP16856. ).
Length = 171
Score = 35.5 bits (78), Expect = 0.17
Identities = 21/75 (28%), Positives = 39/75 (52%), Gaps = 1/75 (1%)
Frame = -2
Query: 260 SDDPTLTALANKYRKSVGQILLRYLIDRGLIPIPKSTNK-QRIAQNIDLFDFQLTFEEVA 84
++D + A + + + L RY + R LIP+P ST + Q I Q + ++ L +E A
Sbjct: 32 AEDQIVVICATSKPEEIDESLRRYFMKRLLIPLPDSTARHQIIVQLLSQHNYCLNDKEFA 91
Query: 83 AINQFNKKHRGIDIS 39
+ Q + G+D++
Sbjct: 92 LLVQRTEGFSGLDVA 106
>AK001267-1|BAA91590.1| 639|Homo sapiens protein ( Homo sapiens
cDNA FLJ10405 fis, clone NT2RM4000496, weakly similar to
SAP1 PROTEIN. ).
Length = 639
Score = 35.5 bits (78), Expect = 0.17
Identities = 21/75 (28%), Positives = 39/75 (52%), Gaps = 1/75 (1%)
Frame = -2
Query: 260 SDDPTLTALANKYRKSVGQILLRYLIDRGLIPIPKSTNK-QRIAQNIDLFDFQLTFEEVA 84
++D + A + + + L RY + R LIP+P ST + Q I Q + ++ L +E A
Sbjct: 500 AEDQIVVICATSKPEEIDESLRRYFMKRLLIPLPDSTARHQIIVQLLSQHNYCLNDKEFA 559
Query: 83 AINQFNKKHRGIDIS 39
+ Q + G+D++
Sbjct: 560 LLVQRTEGFSGLDVA 574
>AC093727-1|AAX81992.1| 639|Homo sapiens unknown protein.
Length = 639
Score = 35.5 bits (78), Expect = 0.17
Identities = 21/75 (28%), Positives = 39/75 (52%), Gaps = 1/75 (1%)
Frame = -2
Query: 260 SDDPTLTALANKYRKSVGQILLRYLIDRGLIPIPKSTNK-QRIAQNIDLFDFQLTFEEVA 84
++D + A + + + L RY + R LIP+P ST + Q I Q + ++ L +E A
Sbjct: 500 AEDQIVVICATSKPEEIDESLRRYFMKRLLIPLPDSTARHQIIVQLLSQHNYCLNDKEFA 559
Query: 83 AINQFNKKHRGIDIS 39
+ Q + G+D++
Sbjct: 560 LLVQRTEGFSGLDVA 574
>BC025709-1|AAH25709.1| 331|Homo sapiens aldo-keto reductase family
7, member A3 (aflatoxin aldehyde reductase) protein.
Length = 331
Score = 35.1 bits (77), Expect = 0.23
Identities = 30/113 (26%), Positives = 51/113 (45%), Gaps = 6/113 (5%)
Frame = -2
Query: 629 LQESLKKLGLXYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFN 450
L+ SLK+L +DL+ +H P + P + ET + Q G +G+SN+
Sbjct: 95 LETSLKRLQCPRVDLFYLHMPDHSTPVE--------ETLRACHQLHQEGKFVELGLSNYA 146
Query: 449 ATQITRLV----SNSYIRPVINQIEVNPTNTQ-EPLVAHC-QSLGIAVMAYSP 309
A ++ + SN +I P + Q N Q E + C + G+ A++P
Sbjct: 147 AWEVAEICTLCKSNGWILPTVYQGMYNAITRQVETELFPCLRHFGLRFYAFNP 199
>AL035413-11|CAI22232.1| 331|Homo sapiens aldo-keto reductase
family 7, member A3 (aflatoxin aldehyde reductase)
protein.
Length = 331
Score = 35.1 bits (77), Expect = 0.23
Identities = 30/113 (26%), Positives = 51/113 (45%), Gaps = 6/113 (5%)
Frame = -2
Query: 629 LQESLKKLGLXYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFN 450
L+ SLK+L +DL+ +H P + P + ET + Q G +G+SN+
Sbjct: 95 LETSLKRLQCPRVDLFYLHMPDHSTPVE--------ETLRACHQLHQEGKFVELGLSNYA 146
Query: 449 ATQITRLV----SNSYIRPVINQIEVNPTNTQ-EPLVAHC-QSLGIAVMAYSP 309
A ++ + SN +I P + Q N Q E + C + G+ A++P
Sbjct: 147 AWEVAEICTLCKSNGWILPTVYQGMYNAITRQVETELFPCLRHFGLRFYAFNP 199
>AK131086-1|BAC85136.1| 217|Homo sapiens FLJ00288 protein protein.
Length = 217
Score = 33.5 bits (73), Expect = 0.70
Identities = 25/80 (31%), Positives = 31/80 (38%), Gaps = 5/80 (6%)
Frame = +1
Query: 52 PLCFLLNWLMAATSSNVNWKSNRSMF*AILCLFVDFGIGIRPLSI-----KYLSRICPTL 216
PL ++ W M A S + W S ++ C G+G PLS L R P
Sbjct: 128 PLLYMTEWFMCAFSRTLPWSSVLRVWDMFFCEGTGLGLGGAPLSPAAHSGASLCRETPKS 187
Query: 217 FLYLLASAVRVGSSERGGGA 276
FL L A G GGA
Sbjct: 188 FLVLTAHPPCRGQDHLPGGA 207
>L35546-1|AAA65028.1| 274|Homo sapiens gamma-glutamylcysteine
synthetase light subunit protein.
Length = 274
Score = 30.3 bits (65), Expect = 6.5
Identities = 23/109 (21%), Positives = 52/109 (47%), Gaps = 2/109 (1%)
Frame = -2
Query: 632 ALQESLKKLGLXYIDLYLIHFPIATKPDDSPDNIDYLET-WQGMQDARQLGLARSIGVSN 456
A+ + LG+ +D +I P D ++++L+ W+ +++ Q +IG S+
Sbjct: 109 AVDMACSVLGVAQLDSVIIASPPIE--DGVNLSLEHLQPYWEELENLVQSKKIVAIGTSD 166
Query: 455 FNATQITRLVSNSYIRPVINQIEVNPTNTQEP-LVAHCQSLGIAVMAYS 312
+ TQ+ +L + ++P NQ+ + P L A + I ++ ++
Sbjct: 167 LDKTQLEQLYQWAQVKPNSNQVNLASCCVMPPDLTAFAKQFDIQLLTHN 215
>CR541833-1|CAG46632.1| 274|Homo sapiens GCLM protein.
Length = 274
Score = 30.3 bits (65), Expect = 6.5
Identities = 23/109 (21%), Positives = 52/109 (47%), Gaps = 2/109 (1%)
Frame = -2
Query: 632 ALQESLKKLGLXYIDLYLIHFPIATKPDDSPDNIDYLET-WQGMQDARQLGLARSIGVSN 456
A+ + LG+ +D +I P D ++++L+ W+ +++ Q +IG S+
Sbjct: 109 AVDMACSVLGVAQLDSVIIASPPIE--DGVNLSLEHLQPYWEELENLVQSKKIVAIGTSD 166
Query: 455 FNATQITRLVSNSYIRPVINQIEVNPTNTQEP-LVAHCQSLGIAVMAYS 312
+ TQ+ +L + ++P NQ+ + P L A + I ++ ++
Sbjct: 167 LDKTQLEQLYQWAQVKPNSNQVNLASCCVMPPDLTAFAKQFDIQLLTHN 215
>BC041809-1|AAH41809.1| 274|Homo sapiens glutamate-cysteine ligase,
modifier subunit protein.
Length = 274
Score = 30.3 bits (65), Expect = 6.5
Identities = 23/109 (21%), Positives = 52/109 (47%), Gaps = 2/109 (1%)
Frame = -2
Query: 632 ALQESLKKLGLXYIDLYLIHFPIATKPDDSPDNIDYLET-WQGMQDARQLGLARSIGVSN 456
A+ + LG+ +D +I P D ++++L+ W+ +++ Q +IG S+
Sbjct: 109 AVDMACSVLGVAQLDSVIIASPPIE--DGVNLSLEHLQPYWEELENLVQSKKIVAIGTSD 166
Query: 455 FNATQITRLVSNSYIRPVINQIEVNPTNTQEP-LVAHCQSLGIAVMAYS 312
+ TQ+ +L + ++P NQ+ + P L A + I ++ ++
Sbjct: 167 LDKTQLEQLYQWAQVKPNSNQVNLASCCVMPPDLTAFAKQFDIQLLTHN 215
>AY773965-1|AAV28733.1| 274|Homo sapiens glutamate-cysteine ligase,
modifier subunit protein.
Length = 274
Score = 30.3 bits (65), Expect = 6.5
Identities = 23/109 (21%), Positives = 52/109 (47%), Gaps = 2/109 (1%)
Frame = -2
Query: 632 ALQESLKKLGLXYIDLYLIHFPIATKPDDSPDNIDYLET-WQGMQDARQLGLARSIGVSN 456
A+ + LG+ +D +I P D ++++L+ W+ +++ Q +IG S+
Sbjct: 109 AVDMACSVLGVAQLDSVIIASPPIE--DGVNLSLEHLQPYWEELENLVQSKKIVAIGTSD 166
Query: 455 FNATQITRLVSNSYIRPVINQIEVNPTNTQEP-LVAHCQSLGIAVMAYS 312
+ TQ+ +L + ++P NQ+ + P L A + I ++ ++
Sbjct: 167 LDKTQLEQLYQWAQVKPNSNQVNLASCCVMPPDLTAFAKQFDIQLLTHN 215
>AL117351-10|CAI22976.1| 274|Homo sapiens glutamate-cysteine
ligase, modifier subunit protein.
Length = 274
Score = 30.3 bits (65), Expect = 6.5
Identities = 23/109 (21%), Positives = 52/109 (47%), Gaps = 2/109 (1%)
Frame = -2
Query: 632 ALQESLKKLGLXYIDLYLIHFPIATKPDDSPDNIDYLET-WQGMQDARQLGLARSIGVSN 456
A+ + LG+ +D +I P D ++++L+ W+ +++ Q +IG S+
Sbjct: 109 AVDMACSVLGVAQLDSVIIASPPIE--DGVNLSLEHLQPYWEELENLVQSKKIVAIGTSD 166
Query: 455 FNATQITRLVSNSYIRPVINQIEVNPTNTQEP-LVAHCQSLGIAVMAYS 312
+ TQ+ +L + ++P NQ+ + P L A + I ++ ++
Sbjct: 167 LDKTQLEQLYQWAQVKPNSNQVNLASCCVMPPDLTAFAKQFDIQLLTHN 215
>AL049796-2|CAI21813.1| 274|Homo sapiens glutamate-cysteine ligase,
modifier subunit protein.
Length = 274
Score = 30.3 bits (65), Expect = 6.5
Identities = 23/109 (21%), Positives = 52/109 (47%), Gaps = 2/109 (1%)
Frame = -2
Query: 632 ALQESLKKLGLXYIDLYLIHFPIATKPDDSPDNIDYLET-WQGMQDARQLGLARSIGVSN 456
A+ + LG+ +D +I P D ++++L+ W+ +++ Q +IG S+
Sbjct: 109 AVDMACSVLGVAQLDSVIIASPPIE--DGVNLSLEHLQPYWEELENLVQSKKIVAIGTSD 166
Query: 455 FNATQITRLVSNSYIRPVINQIEVNPTNTQEP-LVAHCQSLGIAVMAYS 312
+ TQ+ +L + ++P NQ+ + P L A + I ++ ++
Sbjct: 167 LDKTQLEQLYQWAQVKPNSNQVNLASCCVMPPDLTAFAKQFDIQLLTHN 215
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 100,431,954
Number of Sequences: 237096
Number of extensions: 2208211
Number of successful extensions: 5322
Number of sequences better than 10.0: 121
Number of HSP's better than 10.0 without gapping: 4900
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5092
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 7615267504
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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