Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P12_F_O10
(795 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
U37143-1|AAC50370.2| 502|Homo sapiens cytochrome P450 monooxyge... 105 1e-22
BC032594-1|AAH32594.1| 502|Homo sapiens cytochrome P450, family... 105 1e-22
AY426985-1|AAQ93356.1| 502|Homo sapiens cytochrome P450, family... 105 1e-22
AF272142-1|AAM44456.1| 502|Homo sapiens cytochrome P450 protein. 105 1e-22
AB080265-1|BAB85489.1| 502|Homo sapiens cytochrome P450 2J2 pro... 105 1e-22
AF144566-1|AAD30164.1| 339|Homo sapiens cytochrome P450 epoxyge... 105 2e-22
EF122242-1|ABO41977.1| 321|Homo sapiens cytochrome P450 2F1 var... 99 9e-21
AY220845-1|AAO49806.1| 516|Homo sapiens cytochrome P450 protein. 99 2e-20
BC067430-1|AAH67430.1| 491|Homo sapiens cytochrome P450, family... 98 4e-20
EF122241-1|ABO41976.1| 491|Homo sapiens cytochrome P450 2F1 var... 97 9e-20
AF182277-1|AAF13602.1| 491|Homo sapiens cytochrome P450-2B6 pro... 97 9e-20
M29873-1|AAA52143.1| 377|Homo sapiens CYP2B protein. 95 3e-19
BC067431-1|AAH67431.1| 491|Homo sapiens cytochrome P450, family... 95 3e-19
BC041174-1|AAH41174.1| 377|Homo sapiens CYP2B7P1 protein protein. 95 3e-19
M29874-1|AAA52144.1| 491|Homo sapiens CYP2B protein. 95 3e-19
DQ298753-1|ABB84469.1| 491|Homo sapiens cytochrome P450, family... 95 3e-19
BC109056-1|AAI09057.1| 320|Homo sapiens CYP2F1 protein protein. 95 3e-19
AK223113-1|BAD96833.1| 512|Homo sapiens cytochrome P450, family... 95 3e-19
AC023172-1|AAF32444.1| 491|Homo sapiens CYP2B6 protein. 95 3e-19
X04300-1|CAA27843.1| 512|Homo sapiens P-450 c protein. 94 5e-19
X02612-1|CAA26458.1| 512|Homo sapiens cytochrome P(1)-450 protein. 94 5e-19
EF094025-1|ABK41999.1| 512|Homo sapiens cytochrome P450, family... 94 5e-19
BC023019-1|AAH23019.1| 512|Homo sapiens cytochrome P450, family... 94 5e-19
AF253322-1|AAK25727.1| 512|Homo sapiens cytochrome P450 protein. 94 5e-19
K03191-1|AAA52139.1| 512|Homo sapiens CYP1A1 protein. 94 6e-19
AY871801-1|AAX62803.1| 483|Homo sapiens cytochrome P450 family ... 94 6e-19
DQ282158-1|ABB77906.1| 497|Homo sapiens cytochrome P450 2D6 pro... 93 1e-18
DQ282157-1|ABB77905.1| 497|Homo sapiens cytochrome P450 2D6 pro... 93 1e-18
DQ282153-1|ABB77901.1| 497|Homo sapiens cytochrome P450 2D6 pro... 93 1e-18
X08006-1|CAA30807.1| 497|Homo sapiens cytochrome P450 db1 protein. 93 1e-18
M33388-1|AAA53500.1| 497|Homo sapiens cytochrome P450 IID6 prot... 93 1e-18
M20403-1|AAA52153.1| 497|Homo sapiens CYP2D protein. 93 1e-18
DQ282160-1|ABB77908.1| 497|Homo sapiens cytochrome P450 2D6 pro... 93 1e-18
DQ282159-1|ABB77907.1| 497|Homo sapiens cytochrome P450 2D6 pro... 93 1e-18
DQ282156-1|ABB77904.1| 497|Homo sapiens cytochrome P450 2D6 pro... 93 1e-18
DQ282151-1|ABB77899.1| 496|Homo sapiens cytochrome P450 2D6 pro... 93 1e-18
DQ282147-1|ABB77898.1| 497|Homo sapiens cytochrome P450 2D6 pro... 93 1e-18
DQ282146-1|ABB77897.1| 497|Homo sapiens cytochrome P450 2D6 pro... 93 1e-18
DQ282145-1|ABB77896.1| 497|Homo sapiens cytochrome P450 2D6 pro... 93 1e-18
DQ282144-1|ABB77895.1| 497|Homo sapiens cytochrome P450 2D6 pro... 93 1e-18
BC126858-1|AAI26859.1| 497|Homo sapiens cytochrome P450, family... 93 1e-18
BC106758-1|AAI06759.1| 497|Homo sapiens cytochrome P450, family... 93 1e-18
BC075024-1|AAH75024.1| 497|Homo sapiens cytochrome P450, family... 93 1e-18
BC075023-1|AAH75023.1| 497|Homo sapiens cytochrome P450, family... 93 1e-18
BC067432-1|AAH67432.1| 497|Homo sapiens cytochrome P450, family... 93 1e-18
AY545216-1|AAS55001.1| 497|Homo sapiens cytochrome P4502D6 prot... 93 1e-18
AK223108-1|BAD96828.1| 512|Homo sapiens cytochrome P450, family... 92 2e-18
DQ282154-1|ABB77902.1| 497|Homo sapiens cytochrome P450 2D6 pro... 91 3e-18
AF372573-1|AAL69652.1| 495|Homo sapiens cytochrome P450 2F1 pro... 91 3e-18
DQ282155-1|ABB77903.1| 497|Homo sapiens cytochrome P450 2D6 pro... 91 4e-18
J02906-1|AAA52156.1| 491|Homo sapiens CYP2F1 protein. 91 6e-18
DQ282152-1|ABB77900.1| 497|Homo sapiens cytochrome P450 2D6 pro... 89 1e-17
DQ211354-2|ABB01372.1| 497|Homo sapiens cytochrome P450 2D6 pro... 89 1e-17
DQ211353-2|ABB01371.1| 497|Homo sapiens cytochrome P450 2D6 pro... 89 1e-17
DQ211353-1|ABB01370.1| 497|Homo sapiens cytochrome P450 2D6 pro... 89 1e-17
AY310359-1|AAQ76692.1| 484|Homo sapiens cytochrome P450 1A1 var... 88 3e-17
AM236046-1|CAJ84703.1| 229|Homo sapiens cytochrome P450 1A1 pro... 88 3e-17
S46963-1|AAB23864.2| 477|Homo sapiens cytochrome P-450 protein. 87 7e-17
M21939-1|AAA52158.1| 485|Homo sapiens CYP2C protein. 87 7e-17
M15331-1|AAA52157.1| 485|Homo sapiens CYP2C protein. 87 7e-17
L16880-1|AAD13466.1| 273|Homo sapiens cytochrome P-450 2C protein. 87 7e-17
D00173-1|BAA00123.1| 487|Homo sapiens cytochrome P-450 protein. 87 7e-17
DQ282162-1|ABB77909.1| 500|Homo sapiens cytochrome P450 2D6 pro... 87 7e-17
BC125054-1|AAI25055.1| 490|Homo sapiens cytochrome P450, family... 87 7e-17
AY702706-1|AAT94065.1| 490|Homo sapiens cytochrome P450, family... 87 7e-17
AY341248-1|AAP88931.1| 490|Homo sapiens cytochrome P450, family... 87 7e-17
AL359672-1|CAH71303.1| 490|Homo sapiens cytochrome P450, family... 87 7e-17
M21941-1|AAA52160.1| 480|Homo sapiens CYP2C protein. 86 1e-16
M61854-1|AAB59426.1| 490|Homo sapiens cytochrome protein. 86 2e-16
AY796203-1|AAV41877.1| 490|Homo sapiens cytochrome P450, family... 86 2e-16
AL583836-2|CAH74068.1| 490|Homo sapiens cytochrome P450, family... 86 2e-16
AL133513-2|CAH73444.1| 490|Homo sapiens cytochrome P450, family... 86 2e-16
Y00498-1|CAA68550.1| 490|Homo sapiens IIC2 protein. 85 2e-16
X13930-1|CAA32118.1| 494|Homo sapiens protein ( Human CYP2A4 mR... 85 2e-16
X13897-1|CAA32097.1| 489|Homo sapiens protein ( Human mRNA for ... 85 2e-16
M17398-1|AAA35740.1| 393|Homo sapiens protein ( Human cytochrom... 85 2e-16
M17397-1|AAA35739.1| 490|Homo sapiens protein ( Human cytochrom... 85 2e-16
BC096255-1|AAH96255.1| 494|Homo sapiens cytochrome P450, family... 85 2e-16
AY514490-1|AAR89907.1| 490|Homo sapiens cytochrome P450, family... 85 2e-16
AY513608-1|AAR90939.1| 494|Homo sapiens cytochrome P450 2A13 va... 85 2e-16
AL359672-5|CAH71307.1| 490|Homo sapiens cytochrome P450, family... 85 2e-16
U22028-1|AAB40519.1| 494|Homo sapiens cytochrome P450 protein. 85 3e-16
BC020596-1|AAH20596.1| 490|Homo sapiens cytochrome P450, family... 85 3e-16
M33318-1|AAA52067.1| 494|Homo sapiens CYP2A protein. 85 4e-16
M21942-1|AAA52161.1| 462|Homo sapiens CYP2C protein. 85 4e-16
BC096256-1|AAH96256.1| 494|Homo sapiens cytochrome P450, family... 85 4e-16
BC096254-1|AAH96254.1| 494|Homo sapiens cytochrome P450, family... 85 4e-16
BC096253-1|AAH96253.3| 494|Homo sapiens cytochrome P450, family... 85 4e-16
AY513609-1|AAR90940.1| 494|Homo sapiens cytochrome P450 2A13 va... 85 4e-16
AY513606-1|AAR90937.1| 494|Homo sapiens cytochrome P450 2A13 va... 85 4e-16
AY513605-1|AAR90936.1| 494|Homo sapiens cytochrome P450 2A13 va... 85 4e-16
AY513604-1|AAR90935.1| 494|Homo sapiens cytochrome P450 2A13 va... 85 4e-16
AF209774-1|AAG35775.1| 494|Homo sapiens cytochrome P450 2A13 pr... 85 4e-16
AF182275-1|AAF13600.1| 494|Homo sapiens cytochrome P450-2A6 pro... 85 4e-16
M61856-1|AAB59356.1| 490|Homo sapiens cytochrome protein. 84 5e-16
L16876-1|AAA02630.1| 490|Homo sapiens cytochrome P-4502C18 prot... 84 5e-16
BC096259-1|AAH96259.1| 443|Homo sapiens CYP2C18 protein protein. 84 5e-16
BC096258-1|AAH96258.1| 490|Homo sapiens cytochrome P450, family... 84 5e-16
BC096257-1|AAH96257.1| 490|Homo sapiens cytochrome P450, family... 84 5e-16
BC069666-1|AAH69666.1| 490|Homo sapiens cytochrome P450, family... 84 5e-16
AL583836-1|CAH74067.1| 490|Homo sapiens cytochrome P450, family... 84 5e-16
U22029-1|AAB40520.1| 494|Homo sapiens cytochrome P450 protein. 84 6e-16
BC096260-1|AAH96260.1| 431|Homo sapiens CYP2C18 protein protein. 84 6e-16
M33317-1|AAA52138.1| 494|Homo sapiens CYP2A protein. 83 8e-16
AK223510-1|BAD97230.1| 490|Homo sapiens cytochrome P450, family... 83 1e-15
J02843-1|AAA52155.1| 493|Homo sapiens protein ( Human cytochrom... 83 1e-15
J02625-1|AAA35743.1| 493|Homo sapiens protein ( Human cytochrom... 83 1e-15
DQ515958-1|ABF47105.1| 493|Homo sapiens cytochrome P450, family... 83 1e-15
DQ149222-1|AAZ77710.1| 493|Homo sapiens cytochrome P450 2E1 pro... 83 1e-15
AL161645-2|CAH70047.1| 493|Homo sapiens cytochrome P450, family... 83 1e-15
AF182276-1|AAF13601.1| 493|Homo sapiens cytochrome P450-2E1 pro... 83 1e-15
U22027-1|AAB40518.1| 494|Homo sapiens cytochrome P450 protein. 82 2e-15
BC067433-1|AAH67433.1| 493|Homo sapiens cytochrome P450, family... 82 2e-15
AF084225-1|AAD13753.1| 462|Homo sapiens cytochrome P450 2E1 pro... 82 2e-15
BC117165-1|AAI17166.1| 494|Homo sapiens cytochrome P450, family... 81 5e-15
BC067435-1|AAH67435.1| 493|Homo sapiens cytochrome P450, family... 81 6e-15
S63426-1|ABB76283.1| 214|Homo sapiens (S)-mephenytoin hydroxyla... 79 2e-14
L39098-1|AAL31347.1| 160|Homo sapiens S-mephenytoin 4-hydroxyla... 78 4e-14
BC070317-1|AAH70317.1| 162|Homo sapiens CYP2C9 protein protein. 78 4e-14
BC020754-1|AAH20754.1| 162|Homo sapiens CYP2C9 protein protein. 78 4e-14
BC104909-1|AAI04910.1| 501|Homo sapiens cytochrome P450, family... 77 7e-14
BC104907-1|AAI04908.1| 501|Homo sapiens cytochrome P450, family... 77 7e-14
AY323817-1|AAQ23114.1| 501|Homo sapiens cytochrome P450 2R1 pro... 77 7e-14
BC132767-1|AAI32768.1| 544|Homo sapiens cytochrome P450, family... 76 1e-13
AY343323-1|AAQ21380.1| 544|Homo sapiens cytochrome P450 protein. 76 1e-13
AM233520-1|CAJ80723.1| 189|Homo sapiens cytochrome P450 1A1 pro... 76 1e-13
AM233519-1|CAJ80722.1| 189|Homo sapiens cytochrome P450 1A1 pro... 76 1e-13
AB209492-1|BAD92729.1| 566|Homo sapiens Debrisoquine 4-hydroxyl... 62 1e-12
Z00036-1|CAA77335.1| 515|Homo sapiens protein ( Human mRNA for ... 71 4e-12
M55053-1|AAA52146.1| 515|Homo sapiens cytochrome P3-450 protein. 71 4e-12
M31667-1|AAA52163.1| 515|Homo sapiens CYP1A2 protein. 71 4e-12
DQ022432-1|AAY26399.1| 516|Homo sapiens cytochrome P450, family... 71 4e-12
BC067429-1|AAH67429.1| 516|Homo sapiens cytochrome P450, family... 71 4e-12
BC067428-1|AAH67428.1| 516|Homo sapiens cytochrome P450, family... 71 4e-12
BC067426-1|AAH67426.1| 516|Homo sapiens cytochrome P450, family... 71 4e-12
BC067425-1|AAH67425.1| 516|Homo sapiens cytochrome P450, family... 71 4e-12
BC067424-1|AAH67424.1| 516|Homo sapiens cytochrome P450, family... 71 4e-12
AF253322-2|AAK25728.1| 516|Homo sapiens cytochrome P450 protein. 71 4e-12
AF182274-1|AAF13599.1| 516|Homo sapiens cytochrome P450-1A2 pro... 70 8e-12
BC025761-1|AAH25761.2| 490|Homo sapiens cytochrome P450, family... 69 1e-11
X13929-1|CAA32117.1| 448|Homo sapiens P-450 IIA3 protein (1 is ... 69 2e-11
L00389-1|AAA35738.1| 516|Homo sapiens protein ( Human cytochrom... 69 2e-11
BC067427-1|AAH67427.1| 516|Homo sapiens cytochrome P450, family... 69 3e-11
L07093-1|AAA36660.1| 468|Homo sapiens cytochrome P450 protein. 68 3e-11
BC033691-1|AAH33691.1| 504|Homo sapiens cytochrome P450, family... 66 1e-10
AY358603-1|AAQ88966.1| 504|Homo sapiens Cytochrome p450 protein. 66 1e-10
AK027605-1|BAB55227.1| 564|Homo sapiens protein ( Homo sapiens ... 66 1e-10
AF335278-1|AAK13498.1| 504|Homo sapiens cytochrome P450 2S1 pro... 66 1e-10
M24499-1|AAA36403.1| 373|Homo sapiens cytochrome P450db1 protein. 58 4e-08
M33189-1|AAA35737.1| 500|Homo sapiens protein ( Human debrisoqu... 58 5e-08
AK000366-1|BAA91114.1| 408|Homo sapiens protein ( Homo sapiens ... 53 1e-06
M63871-1|AAA59984.1| 508|Homo sapiens CYP17 protein. 52 2e-06
M19489-1|AAA36405.1| 508|Homo sapiens CYP17 protein. 52 2e-06
M14564-1|AAA52151.1| 508|Homo sapiens CYP17 protein. 52 2e-06
DQ530598-1|ABF50972.1| 508|Homo sapiens cytochrome P450, family... 52 2e-06
BT020000-1|AAV38803.1| 508|Homo sapiens cytochrome P450, family... 52 2e-06
BC063388-1|AAH63388.1| 508|Homo sapiens cytochrome P450, family... 52 2e-06
BC062997-1|AAH62997.1| 508|Homo sapiens cytochrome P450, family... 52 2e-06
AL358790-3|CAI52498.1| 508|Homo sapiens cytochrome P450, family... 52 2e-06
M31153-1|AAA52140.1| 508|Homo sapiens CYP17 protein. 52 3e-06
M21940-1|AAA52159.1| 383|Homo sapiens CYP2C protein. 51 4e-06
U56438-1|AAC50809.1| 543|Homo sapiens dioxin-inducible cytochro... 50 7e-06
U03688-1|AAA19567.1| 543|Homo sapiens cytochrome P450 protein. 50 7e-06
DQ359216-1|ABC95161.1| 347|Homo sapiens dioxin-inducible cytoch... 50 7e-06
BT019979-1|AAV38782.1| 543|Homo sapiens cytochrome P450, family... 50 7e-06
BC012049-1|AAH12049.1| 543|Homo sapiens cytochrome P450, family... 50 7e-06
AY393998-1|AAQ87875.1| 543|Homo sapiens cytochrome P450, family... 50 7e-06
AF450132-1|AAM50512.1| 543|Homo sapiens cytochrome P450 CYP1B1 ... 50 7e-06
AC009229-2|AAY15039.1| 543|Homo sapiens unknown protein. 50 7e-06
BT020001-1|AAV38804.1| 543|Homo sapiens cytochrome P450, family... 50 1e-05
BC109084-1|AAI09085.1| 448|Homo sapiens CYP24A1 protein protein. 46 2e-04
BC109083-1|AAI09084.1| 448|Homo sapiens CYP24A1 protein protein. 46 2e-04
AL138805-3|CAM27343.1| 448|Homo sapiens cytochrome P450, family... 46 2e-04
AL138805-2|CAB91829.1| 514|Homo sapiens cytochrome P450, family... 46 2e-04
L13286-1|AAA62379.1| 513|Homo sapiens 1,25-dihydroxyvitamin D3 ... 46 2e-04
AY513607-1|AAR90938.1| 100|Homo sapiens truncated cytochrome P4... 45 3e-04
CR456430-1|CAG30316.1| 446|Homo sapiens CYP2D6 protein. 45 4e-04
BC106757-1|AAI06758.1| 446|Homo sapiens cytochrome P450, family... 45 4e-04
BC066877-1|AAH66877.1| 446|Homo sapiens CYP2D6 protein protein. 45 4e-04
J04813-1|AAA02993.1| 502|Homo sapiens cytochrome P450 PCN3 prot... 42 0.002
DQ680079-1|ABG25922.1| 347|Homo sapiens truncated cytochrome P4... 42 0.002
BC033862-1|AAH33862.1| 502|Homo sapiens cytochrome P450, family... 42 0.002
AC005020-1|AAS02016.1| 502|Homo sapiens unknown protein. 42 0.002
J04449-1|AAA35747.1| 502|Homo sapiens cytochrome P450 nifedipin... 42 0.003
AK223008-1|BAD96728.1| 502|Homo sapiens cytochrome P450, family... 42 0.003
DQ211355-2|ABB01373.1| 117|Homo sapiens cytochrome P450 2D6 pro... 42 0.003
X12387-1|CAA30944.1| 503|Homo sapiens protein ( Human mRNA for ... 41 0.004
M18907-1|AAA35745.1| 503|Homo sapiens protein ( Human P450 mRNA... 41 0.004
M14096-1|AAA35744.1| 503|Homo sapiens protein ( Human cytochrom... 41 0.004
DQ924960-1|ABI96208.1| 503|Homo sapiens cytochrome P450 family ... 41 0.004
DQ005611-1|AAY16980.1| 503|Homo sapiens cytochrome P450, family... 41 0.004
BC101631-1|AAI01632.1| 503|Homo sapiens cytochrome P450, subfam... 41 0.004
BC069418-1|AAH69418.1| 503|Homo sapiens cytochrome P450, family... 41 0.004
AJ563375-1|CAD91343.1| 503|Homo sapiens cytochrome P450 protein. 41 0.004
AF280107-2|AAG32290.1| 503|Homo sapiens cytochrome P450 polypep... 41 0.004
AF209389-1|AAF21034.1| 503|Homo sapiens cytochrome P450 IIIA4 p... 41 0.004
AF182273-1|AAF13598.1| 503|Homo sapiens cytochrome P450-3A4 pro... 41 0.004
DQ372705-1|ABD16216.1| 150|Homo sapiens mutant cytochrome p450 ... 41 0.006
AF280107-4|AAG32288.1| 106|Homo sapiens cytochrome P450 polypep... 39 0.018
AF171066-1|AAG43404.1| 112|Homo sapiens CYP1B1 variant protein. 39 0.024
AY390425-1|AAQ92353.1| 503|Homo sapiens cytochrome P450 CYP3A43... 38 0.055
AY390424-1|AAQ92352.1| 503|Homo sapiens cytochrome P450 CYP3A43... 38 0.055
AF337813-1|AAK38841.1| 503|Homo sapiens cytochrome P450 subfami... 38 0.055
AF319634-1|AAK00325.1| 503|Homo sapiens cytochrome P450 CYP3A43... 38 0.055
AF280111-1|AAG33012.1| 250|Homo sapiens cytochrome P450 subfami... 38 0.055
AF280110-1|AAG33011.1| 420|Homo sapiens cytochrome P450 subfami... 38 0.055
AF280109-1|AAG33010.1| 504|Homo sapiens cytochrome P450 subfami... 38 0.055
AF280108-1|AAG33009.1| 503|Homo sapiens cytochrome P450 subfami... 38 0.055
AC011904-5|AAS07394.1| 504|Homo sapiens unknown protein. 38 0.055
AC011904-4|AAS07395.1| 503|Homo sapiens unknown protein. 38 0.055
BC022539-1|AAH22539.1| 500|Homo sapiens cytochrome P450, family... 37 0.073
AF094480-1|AAD41244.1| 500|Homo sapiens cholesterol 24-hydroxyl... 37 0.073
M13785-1|AAA35742.1| 504|Homo sapiens protein ( Human liver glu... 37 0.096
D00003-1|BAA00001.1| 504|Homo sapiens cytochrome P-450 protein. 37 0.096
BC012027-1|AAH12027.1| 168|Homo sapiens CYP2U1 protein protein. 36 0.13
AF280107-1|AAG32291.1| 106|Homo sapiens cytochrome P450 polypep... 36 0.22
M61858-1|AAA52145.1| 370|Homo sapiens CYP2C17 protein. 35 0.29
X54807-1|CAA38578.1| 56|Homo sapiens unspecific monooxygenase ... 34 0.51
AL512656-1|CAI15290.1| 488|Homo sapiens annexin A7 protein. 34 0.51
AL353731-3|CAI52484.1| 488|Homo sapiens annexin A7 protein. 34 0.51
BX538127-1|CAD98029.1| 310|Homo sapiens hypothetical protein pr... 34 0.68
D00408-1|BAA00310.1| 503|Homo sapiens cytochrome P-450 HFLa pro... 32 2.1
BC067436-1|AAH67436.1| 503|Homo sapiens cytochrome P450, family... 32 2.1
AF315325-1|AAG48618.1| 535|Homo sapiens cytochrome P450 variant... 32 2.1
AF280107-3|AAG32289.1| 503|Homo sapiens cytochrome P450 polypep... 32 2.1
X58906-1|CAA41709.1| 495|Homo sapiens steroid 21-monooxygenase ... 32 2.7
X58904-1|CAA41707.1| 371|Homo sapiens steroid 21-monooxygenase ... 32 2.7
X58902-1|CAA41706.1| 372|Homo sapiens steroid 21-monooxygenase ... 32 2.7
X58900-1|CAA41704.1| 372|Homo sapiens steroid 21-monooxygenase ... 32 2.7
M28548-1|AAA52065.1| 495|Homo sapiens protein ( Human mutant 21... 32 2.7
M26856-1|AAA52064.1| 495|Homo sapiens protein ( Human 21-hydrox... 32 2.7
M21550-1|AAA52063.1| 495|Homo sapiens CYP21 protein. 32 2.7
M13936-1|AAA59695.1| 494|Homo sapiens CYP21P protein. 32 2.7
M12792-1|AAB59440.1| 494|Homo sapiens steroid 21-hydroxylase pr... 32 2.7
BX679671-8|CAM26070.1| 494|Homo sapiens cytochrome P450, family... 32 2.7
BC125182-1|AAI25183.1| 494|Homo sapiens cytochrome P450, family... 32 2.7
BC125181-1|AAI25182.1| 495|Homo sapiens cytochrome P450, family... 32 2.7
AM183951-1|CAJ75805.1| 494|Homo sapiens steroid 21-hydroxylase,... 32 2.7
AM183950-1|CAJ75804.1| 494|Homo sapiens steroid 21-hydroxylase,... 32 2.7
AM183949-1|CAJ75803.1| 494|Homo sapiens steroid 21-hydroxylase,... 32 2.7
AM183948-1|CAJ75802.1| 494|Homo sapiens steroid 21-hydroxylase ... 32 2.7
AM183947-1|CAJ75801.1| 494|Homo sapiens steroid 21-hydroxylase,... 32 2.7
AM086565-1|CAJ31104.1| 494|Homo sapiens steroid 21-hydroxylase,... 32 2.7
AL929593-1|CAI41779.1| 495|Homo sapiens cytochrome P450, family... 32 2.7
AL662849-18|CAI17479.1| 495|Homo sapiens cytochrome P450, famil... 32 2.7
AL645922-24|CAI41754.1| 495|Homo sapiens cytochrome P450, famil... 32 2.7
AL049547-7|CAB89301.1| 495|Homo sapiens dJ34F7.3 (cytochrome P4... 32 2.7
AF019413-2|AAB67982.1| 495|Homo sapiens cytochrome P450 21-hydr... 32 2.7
AM183946-1|CAJ75800.1| 494|Homo sapiens steroid 21-hydroxylase,... 31 4.8
AM183945-1|CAJ75799.1| 494|Homo sapiens steroid 21-hydroxylase,... 31 6.3
X56452-1|CAA39833.1| 56|Homo sapiens unspecific monooxygenase ... 30 8.4
EF122245-1|ABO41980.1| 54|Homo sapiens cytochrome P450 2F1 var... 30 8.4
AF081569-1|AAD25924.1| 52|Homo sapiens cytochrome P450 protein. 30 8.4
>U37143-1|AAC50370.2| 502|Homo sapiens cytochrome P450
monooxygenase CYP2J2 protein.
Length = 502
Score = 105 bits (253), Expect = 1e-22
Identities = 70/214 (32%), Positives = 106/214 (49%), Gaps = 4/214 (1%)
Frame = +1
Query: 94 RRHRGLCYPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 273
+R R YPPGP LP +GN V F+ HL Q + +KYGNL L LG I+ V+
Sbjct: 36 KRRRPKNYPPGPWRLPFLGNFFLV-----DFEQSHLEVQLFVKKYGNLFSLELGDISAVL 90
Query: 274 VTGIELIKE--VSNREVFEGRPDGFFYTMRS-FGKKLGLVFSDGPTWHRTRRFVLKYLKN 444
+TG+ LIKE + + F RP MR KK GL+ S G W RRF L L+N
Sbjct: 91 ITGLPLIKEALIHMDQNFGNRP---VTPMREHIFKKNGLIMSSGQAWKEQRRFTLTALRN 147
Query: 445 FGYNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQR 624
FG + + I EE + L + + G+P + + + NI+ + G+R++ D
Sbjct: 148 FGLGKKSLEERIQEEAQHLTEAIKEENGQPFDPHFKINNAVSNIICSITFGERFEYQDSW 207
Query: 625 LKKLCNLVMRLFKL-XDMSGGILNFLPFLXHFIP 723
++L L+ + L + + N P++ F+P
Sbjct: 208 FQQLLKLLDEVTYLEASKTCQLYNVFPWIMKFLP 241
>BC032594-1|AAH32594.1| 502|Homo sapiens cytochrome P450, family 2,
subfamily J, polypeptide 2 protein.
Length = 502
Score = 105 bits (253), Expect = 1e-22
Identities = 70/214 (32%), Positives = 106/214 (49%), Gaps = 4/214 (1%)
Frame = +1
Query: 94 RRHRGLCYPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 273
+R R YPPGP LP +GN V F+ HL Q + +KYGNL L LG I+ V+
Sbjct: 36 KRRRPKNYPPGPWRLPFLGNFFLV-----DFEQSHLEVQLFVKKYGNLFSLELGDISAVL 90
Query: 274 VTGIELIKE--VSNREVFEGRPDGFFYTMRS-FGKKLGLVFSDGPTWHRTRRFVLKYLKN 444
+TG+ LIKE + + F RP MR KK GL+ S G W RRF L L+N
Sbjct: 91 ITGLPLIKEALIHMDQNFGNRP---VTPMREHIFKKNGLIMSSGQAWKEQRRFTLTALRN 147
Query: 445 FGYNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQR 624
FG + + I EE + L + + G+P + + + NI+ + G+R++ D
Sbjct: 148 FGLGKKSLEERIQEEAQHLTEAIKEENGQPFDPHFKINNAVSNIICSITFGERFEYQDSW 207
Query: 625 LKKLCNLVMRLFKL-XDMSGGILNFLPFLXHFIP 723
++L L+ + L + + N P++ F+P
Sbjct: 208 FQQLLKLLDEVTYLEASKTCQLYNVFPWIMKFLP 241
>AY426985-1|AAQ93356.1| 502|Homo sapiens cytochrome P450, family 2,
subfamily J, polypeptide 2 protein.
Length = 502
Score = 105 bits (253), Expect = 1e-22
Identities = 70/214 (32%), Positives = 106/214 (49%), Gaps = 4/214 (1%)
Frame = +1
Query: 94 RRHRGLCYPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 273
+R R YPPGP LP +GN V F+ HL Q + +KYGNL L LG I+ V+
Sbjct: 36 KRRRPKNYPPGPWRLPFLGNFFLV-----DFEQSHLEVQLFVKKYGNLFSLELGDISAVL 90
Query: 274 VTGIELIKE--VSNREVFEGRPDGFFYTMRS-FGKKLGLVFSDGPTWHRTRRFVLKYLKN 444
+TG+ LIKE + + F RP MR KK GL+ S G W RRF L L+N
Sbjct: 91 ITGLPLIKEALIHMDQNFGNRP---VTPMREHIFKKNGLIMSSGQAWKEQRRFTLTALRN 147
Query: 445 FGYNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQR 624
FG + + I EE + L + + G+P + + + NI+ + G+R++ D
Sbjct: 148 FGLGKKSLEERIQEEAQHLTEAIKEENGQPFDPHFKINNAVSNIICSITFGERFEYQDSW 207
Query: 625 LKKLCNLVMRLFKL-XDMSGGILNFLPFLXHFIP 723
++L L+ + L + + N P++ F+P
Sbjct: 208 FQQLLKLLDEVTYLEASKTCQLYNVFPWIMKFLP 241
>AF272142-1|AAM44456.1| 502|Homo sapiens cytochrome P450 protein.
Length = 502
Score = 105 bits (253), Expect = 1e-22
Identities = 70/214 (32%), Positives = 106/214 (49%), Gaps = 4/214 (1%)
Frame = +1
Query: 94 RRHRGLCYPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 273
+R R YPPGP LP +GN V F+ HL Q + +KYGNL L LG I+ V+
Sbjct: 36 KRRRPKNYPPGPWRLPFLGNFFLV-----DFEQSHLEVQLFVKKYGNLFSLELGDISAVL 90
Query: 274 VTGIELIKE--VSNREVFEGRPDGFFYTMRS-FGKKLGLVFSDGPTWHRTRRFVLKYLKN 444
+TG+ LIKE + + F RP MR KK GL+ S G W RRF L L+N
Sbjct: 91 ITGLPLIKEALIHMDQNFGNRP---VTPMREHIFKKNGLIMSSGQAWKEQRRFTLTALRN 147
Query: 445 FGYNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQR 624
FG + + I EE + L + + G+P + + + NI+ + G+R++ D
Sbjct: 148 FGLGKKSLEERIQEEAQHLTEAIKEENGQPFDPHFKINNAVSNIICSITFGERFEYQDSW 207
Query: 625 LKKLCNLVMRLFKL-XDMSGGILNFLPFLXHFIP 723
++L L+ + L + + N P++ F+P
Sbjct: 208 FQQLLKLLDEVTYLEASKTCQLYNVFPWIMKFLP 241
>AB080265-1|BAB85489.1| 502|Homo sapiens cytochrome P450 2J2
protein.
Length = 502
Score = 105 bits (253), Expect = 1e-22
Identities = 70/214 (32%), Positives = 106/214 (49%), Gaps = 4/214 (1%)
Frame = +1
Query: 94 RRHRGLCYPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 273
+R R YPPGP LP +GN V F+ HL Q + +KYGNL L LG I+ V+
Sbjct: 36 KRRRPKNYPPGPWRLPFLGNFFLV-----DFEQSHLEVQLFVKKYGNLFSLELGDISAVL 90
Query: 274 VTGIELIKE--VSNREVFEGRPDGFFYTMRS-FGKKLGLVFSDGPTWHRTRRFVLKYLKN 444
+TG+ LIKE + + F RP MR KK GL+ S G W RRF L L+N
Sbjct: 91 ITGLPLIKEALIHMDQNFGNRP---VTPMREHIFKKNGLIMSSGQAWKEQRRFTLTALRN 147
Query: 445 FGYNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQR 624
FG + + I EE + L + + G+P + + + NI+ + G+R++ D
Sbjct: 148 FGLGKKSLEERIQEEAQHLTEAIKEENGQPFDPHFKINNAVSNIICSITFGERFEYQDSW 207
Query: 625 LKKLCNLVMRLFKL-XDMSGGILNFLPFLXHFIP 723
++L L+ + L + + N P++ F+P
Sbjct: 208 FQQLLKLLDEVTYLEASKTCQLYNVFPWIMKFLP 241
>AF144566-1|AAD30164.1| 339|Homo sapiens cytochrome P450
epoxygenase protein.
Length = 339
Score = 105 bits (252), Expect = 2e-22
Identities = 70/214 (32%), Positives = 106/214 (49%), Gaps = 4/214 (1%)
Frame = +1
Query: 94 RRHRGLCYPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 273
+R R YPPGP LP +GN V F+ HL Q + +KYGNL L LG I+ V+
Sbjct: 5 KRRRPKNYPPGPWRLPFLGNFFLV-----DFEQSHLEVQLFVKKYGNLFSLELGDISAVL 59
Query: 274 VTGIELIKE--VSNREVFEGRPDGFFYTMRS-FGKKLGLVFSDGPTWHRTRRFVLKYLKN 444
+TG+ LIKE + + F RP MR KK GL+ S G W RRF L L+N
Sbjct: 60 ITGLPLIKEALIHMDQNFGNRP---VTPMREHIFKKNGLIMSSGQAWKEQRRFTLTALRN 116
Query: 445 FGYNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQR 624
FG + + I EE + L + + G+P + + + NI+ + G+R++ D
Sbjct: 117 FGLGKKGLEERIQEEAQHLTEAIKEENGQPFDPHFKINNAVSNIICSITFGERFEYQDSW 176
Query: 625 LKKLCNLVMRLFKL-XDMSGGILNFLPFLXHFIP 723
++L L+ + L + + N P++ F+P
Sbjct: 177 FQQLLKLLDEVTYLEASKTCQLYNVFPWIMKFLP 210
>EF122242-1|ABO41977.1| 321|Homo sapiens cytochrome P450 2F1
variant protein.
Length = 321
Score = 99 bits (238), Expect = 9e-21
Identities = 67/215 (31%), Positives = 107/215 (49%), Gaps = 3/215 (1%)
Frame = +1
Query: 88 ISRRHRGLCYPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINV 267
+S R +G PPGP PLP++GNL+ + + L S++YG++ + LG V
Sbjct: 22 LSSRDKGKL-PPGPRPLPILGNLLLLCSQDMLTSLTKL-----SKEYGSMYTVHLGPRRV 75
Query: 268 VVVTGIELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLK 441
VV++G + +KE V E F GR D + +F K G+ FS G W R+F ++ L+
Sbjct: 76 VVLSGYQAVKEALVDQGEEFSGRGD--YPAFFNFTKGNGIAFSSGDRWKVLRQFSIQILR 133
Query: 442 NFGYNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQ 621
NFG R + I EE L+ GEP + ++ NI+ ++ G R+D D+
Sbjct: 134 NFGMGKRSIEERILEEGSFLLAELRKTEGEPFDPTFVLSRSVSNIICSVLFGSRFDYDDE 193
Query: 622 RLKKLCNLVMRLFKLXDMS-GGILNFLPFLXHFIP 723
RL + L+ F++ G + N P L ++P
Sbjct: 194 RLLTIIRLINDNFQIMSSPWGELYNIFPSLLDWVP 228
>AY220845-1|AAO49806.1| 516|Homo sapiens cytochrome P450 protein.
Length = 516
Score = 99.1 bits (236), Expect = 2e-20
Identities = 67/213 (31%), Positives = 107/213 (50%), Gaps = 6/213 (2%)
Frame = +1
Query: 115 YPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELI 294
YPPGP PLP +GNL+ V +++ + C + +++G++ L+L VVV+ G+ +
Sbjct: 33 YPPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFNLQLAWTPVVVLNGLAAV 87
Query: 295 KE--VSNREVFEGRPDGFFYTMRSFG-KKLGLVFSD-GPTWHRTRRFVLKYLKNFGYNSR 462
+E V+ E RP Y + FG + G++ S GP W RRF + L+N G +
Sbjct: 88 REAMVTRGEDTADRPPAPIYQVLGFGPRSQGVILSRYGPAWREQRRFSVSTLRNLGLGKK 147
Query: 463 FMNVYIGEECEALVQLRFAD-AGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLC 639
+ ++ EE L FAD AG P N + + N++ L G+R++ D R +L
Sbjct: 148 SLEQWVTEEAACLC-AAFADQAGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLL 206
Query: 640 NLVMR-LFKLXDMSGGILNFLPFLXHFIPRLIG 735
+L L + +LN +P L H IP L G
Sbjct: 207 DLAQEGLKEESGFLREVLNAVPVLPH-IPALAG 238
>BC067430-1|AAH67430.1| 491|Homo sapiens cytochrome P450, family 2,
subfamily B, polypeptide 6 protein.
Length = 491
Score = 97.9 bits (233), Expect = 4e-20
Identities = 65/204 (31%), Positives = 102/204 (50%), Gaps = 4/204 (1%)
Frame = +1
Query: 118 PPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIK 297
PPGP PLP++GNL+ + R+ + + +KYG++ + LG VV++ G+E I+
Sbjct: 31 PPGPRPLPLLGNLLQM---DRRGLLKSFL--RFREKYGDVFTVHLGPRPVVMLCGVEAIR 85
Query: 298 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 471
E V E F GR G + F + G++F++G W RRF + +++FG R +
Sbjct: 86 EALVDKAEAFSGR--GKIAMVDPFFRGYGVIFANGNRWKVLRRFSVTTMRDFGMGKRSVE 143
Query: 472 VYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCNLVM 651
I EE + L++ G + +FH NI+ +V GKR+ DQ K+ NL
Sbjct: 144 ERIQEEAQCLIEELRKSKGALMDPTFLFHSITANIICSIVFGKRFHYQDQEFLKMLNLFY 203
Query: 652 RLFKLXDMSGGIL--NFLPFLXHF 717
+ F L G L F FL +F
Sbjct: 204 QTFSLISSVFGQLFELFSGFLKYF 227
>EF122241-1|ABO41976.1| 491|Homo sapiens cytochrome P450 2F1
variant protein.
Length = 491
Score = 96.7 bits (230), Expect = 9e-20
Identities = 66/215 (30%), Positives = 106/215 (49%), Gaps = 3/215 (1%)
Frame = +1
Query: 88 ISRRHRGLCYPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINV 267
+S R +G PPGP PL ++GNL+ + + L S++YG++ + LG V
Sbjct: 22 LSSRDKGKL-PPGPRPLSILGNLLLLCSQDMLTSLTKL-----SKEYGSMYTVHLGPRRV 75
Query: 268 VVVTGIELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLK 441
VV++G + +KE V E F GR D + +F K G+ FS G W R+F ++ L+
Sbjct: 76 VVLSGYQAVKEALVDQGEEFSGRGD--YPAFFNFTKGNGIAFSSGDRWKVLRQFSIQILR 133
Query: 442 NFGYNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQ 621
NFG R + I EE L+ GEP + ++ NI+ ++ G R+D D+
Sbjct: 134 NFGMGKRSIEERILEEGSFLLAELRKTEGEPFDPTFVLSRSVSNIICSVLFGSRFDYDDE 193
Query: 622 RLKKLCNLVMRLFKLXDMS-GGILNFLPFLXHFIP 723
RL + L+ F++ G + N P L ++P
Sbjct: 194 RLLTIIRLINDNFQIMSSPWGELYNIFPSLLDWVP 228
>AF182277-1|AAF13602.1| 491|Homo sapiens cytochrome P450-2B6
protein.
Length = 491
Score = 96.7 bits (230), Expect = 9e-20
Identities = 64/204 (31%), Positives = 101/204 (49%), Gaps = 4/204 (1%)
Frame = +1
Query: 118 PPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIK 297
PPGP PLP++GNL+ + R+ + + +KYG++ + LG VV++ G+E I+
Sbjct: 31 PPGPRPLPLLGNLLQM---DRRGLLKSFL--RFREKYGDVFTVHLGPRPVVMLCGVEAIR 85
Query: 298 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 471
E V E F GR G + F + G++F++G W RRF + +++FG R +
Sbjct: 86 EALVDKAEAFSGR--GKIAMVDPFFRGYGVIFANGNRWKVLRRFSVTTMRDFGMGKRSVE 143
Query: 472 VYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCNLVM 651
EE + L++ G + +FH NI+ +V GKR+ DQ K+ NL
Sbjct: 144 ERTQEEAQCLIEELRKSKGALMDATFLFHSITANIICSIVFGKRFHYQDQEFLKMLNLFY 203
Query: 652 RLFKLXDMSGGIL--NFLPFLXHF 717
+ F L G L F FL +F
Sbjct: 204 QTFSLISSVFGQLFELFSGFLKYF 227
>M29873-1|AAA52143.1| 377|Homo sapiens CYP2B protein.
Length = 377
Score = 95.1 bits (226), Expect = 3e-19
Identities = 63/204 (30%), Positives = 102/204 (50%), Gaps = 4/204 (1%)
Frame = +1
Query: 118 PPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIK 297
PPGP PLP++GNL+ + R+ + + +KYG++ + LG VV++ G+E I+
Sbjct: 31 PPGPRPLPLLGNLLQM---DRRGLLKSFL--RFREKYGDVFTVHLGPRPVVMLCGVEAIR 85
Query: 298 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 471
E V N E F GR G M + G++F++G W RRF + +++FG R +
Sbjct: 86 EALVDNAEAFSGR--GKIVIMDPVYQGYGMLFANGNRWKVLRRFSVTTMRDFGMGKRSVE 143
Query: 472 VYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCNLVM 651
I +E + L++ G + +FH NI+ ++ GKR+ DQ K NL
Sbjct: 144 ERIQDEAQCLIEELRKSKGALVDPTFLFHSITANIICSIIFGKRFHYQDQEFLKTLNLFC 203
Query: 652 RLFKL-XDMSGGILN-FLPFLXHF 717
+ F L +S + F FL +F
Sbjct: 204 QSFLLISSISSQLFELFSGFLKYF 227
>BC067431-1|AAH67431.1| 491|Homo sapiens cytochrome P450, family 2,
subfamily B, polypeptide 6 protein.
Length = 491
Score = 95.1 bits (226), Expect = 3e-19
Identities = 64/204 (31%), Positives = 101/204 (49%), Gaps = 4/204 (1%)
Frame = +1
Query: 118 PPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIK 297
PPGP PLP++GNL+ + R+ + + +KYG++ + LG VV++ G+E I+
Sbjct: 31 PPGPRPLPLLGNLLQM---DRRGLLKSFL--RFREKYGDVFTVHLGPRPVVMLCGVEAIR 85
Query: 298 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 471
E V E F GR G + F + G++F++G W RRF + +++FG R +
Sbjct: 86 EALVDKAEAFSGR--GKIAMVDPFFRGYGVIFANGNRWKVLRRFSVTTMRDFGMGKRSVE 143
Query: 472 VYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCNLVM 651
I EE + L++ G + +F NI+ +V GKR+ DQ K+ NL
Sbjct: 144 ERIQEEAQCLIEELRKSKGALMDPTFLFQSITANIICSIVFGKRFHYQDQEFLKMLNLFY 203
Query: 652 RLFKLXDMSGGIL--NFLPFLXHF 717
+ F L G L F FL +F
Sbjct: 204 QTFSLISSVFGQLFELFSGFLTYF 227
>BC041174-1|AAH41174.1| 377|Homo sapiens CYP2B7P1 protein protein.
Length = 377
Score = 95.1 bits (226), Expect = 3e-19
Identities = 63/204 (30%), Positives = 102/204 (50%), Gaps = 4/204 (1%)
Frame = +1
Query: 118 PPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIK 297
PPGP PLP++GNL+ + R+ + + +KYG++ + LG VV++ G+E I+
Sbjct: 31 PPGPRPLPLLGNLLQM---DRRGLLKSFL--RFREKYGDVFTVHLGPRPVVMLCGVEAIR 85
Query: 298 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 471
E V N E F GR G M + G++F++G W RRF + +++FG R +
Sbjct: 86 EALVDNAEAFSGR--GKIVIMDPVYQGYGMLFANGNRWKVLRRFSVTTMRDFGMGKRSVE 143
Query: 472 VYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCNLVM 651
I +E + L++ G + +FH NI+ ++ GKR+ DQ K NL
Sbjct: 144 ERIQDEAQCLIEELRKSKGALVDPTFLFHSITANIICSIIFGKRFHYQDQEFLKTLNLFC 203
Query: 652 RLFKL-XDMSGGILN-FLPFLXHF 717
+ F L +S + F FL +F
Sbjct: 204 QSFLLISSISSQLFELFSGFLKYF 227
>M29874-1|AAA52144.1| 491|Homo sapiens CYP2B protein.
Length = 491
Score = 94.7 bits (225), Expect = 3e-19
Identities = 64/204 (31%), Positives = 101/204 (49%), Gaps = 4/204 (1%)
Frame = +1
Query: 118 PPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIK 297
PPGP PLP++GNL+ + R+ + + +KYG++ + LG VV++ G+E I+
Sbjct: 31 PPGPRPLPLLGNLLQM---DRRGLLKSFL--RFREKYGDVFTVHLGPRPVVMLCGVEAIR 85
Query: 298 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 471
E V E F GR G + F + G++F++G W RRF + +++FG R +
Sbjct: 86 EALVDKAEAFSGR--GKIAMVDPFFRGYGVIFANGNRWKVLRRFSVTTMRDFGMGKRSVE 143
Query: 472 VYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCNLVM 651
I EE + L++ G + +F NI+ +V GKR+ DQ K+ NL
Sbjct: 144 ERIQEEAQCLIEELRKSKGALMDPTFLFQSITANIICSIVFGKRFHYQDQEFLKMLNLFY 203
Query: 652 RLFKLXDMSGGIL--NFLPFLXHF 717
+ F L G L F FL +F
Sbjct: 204 QTFSLISSVFGQLFELFSGFLKYF 227
>DQ298753-1|ABB84469.1| 491|Homo sapiens cytochrome P450, family 2,
subfamily B, polypeptide 6 protein.
Length = 491
Score = 94.7 bits (225), Expect = 3e-19
Identities = 64/204 (31%), Positives = 101/204 (49%), Gaps = 4/204 (1%)
Frame = +1
Query: 118 PPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIK 297
PPGP PLP++GNL+ + R+ + + +KYG++ + LG VV++ G+E I+
Sbjct: 31 PPGPRPLPLLGNLLQM---DRRGLLKSFL--RFREKYGDVFTVHLGPRPVVMLCGVEAIR 85
Query: 298 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 471
E V E F GR G + F + G++F++G W RRF + +++FG R +
Sbjct: 86 EALVDKAEAFSGR--GKIAMVDPFFRGYGVIFANGNRWKVLRRFSVTTMRDFGMGKRSVE 143
Query: 472 VYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCNLVM 651
I EE + L++ G + +F NI+ +V GKR+ DQ K+ NL
Sbjct: 144 ERIQEEAQCLIEELRKSKGALMDPTFLFQSITANIICSIVFGKRFHYQDQEFLKMLNLFY 203
Query: 652 RLFKLXDMSGGIL--NFLPFLXHF 717
+ F L G L F FL +F
Sbjct: 204 QTFSLISSVFGQLFELFSGFLKYF 227
>BC109056-1|AAI09057.1| 320|Homo sapiens CYP2F1 protein protein.
Length = 320
Score = 94.7 bits (225), Expect = 3e-19
Identities = 65/215 (30%), Positives = 106/215 (49%), Gaps = 3/215 (1%)
Frame = +1
Query: 88 ISRRHRGLCYPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINV 267
+S R +G PPGP PL ++GNL+ + + L S++YG++ + LG V
Sbjct: 22 LSSRDKGKL-PPGPRPLSILGNLLLLCSQDMLTSLTKL-----SKEYGSMYTVHLGPRRV 75
Query: 268 VVVTGIELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLK 441
VV++G + +KE V E F GR D + +F K G+ FS G W R+F ++ L+
Sbjct: 76 VVLSGYQAVKEALVDQGEEFSGRGD--YPAFFNFTKGNGIAFSSGDRWKVLRQFSIQILR 133
Query: 442 NFGYNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQ 621
NFG R + I EE L+ GEP + ++ NI+ ++ G R+D D+
Sbjct: 134 NFGMGKRSIEERILEEGSFLLAELRKTEGEPFDPTFVLSRSVSNIICSVLFGSRFDYDDE 193
Query: 622 RLKKLCNLVMRLFKLXDMS-GGILNFLPFLXHFIP 723
RL + L+ F++ G + + P L ++P
Sbjct: 194 RLLTIIRLINDNFQIMSSPWGELYDIFPSLLDWVP 228
>AK223113-1|BAD96833.1| 512|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 1 variant protein.
Length = 512
Score = 94.7 bits (225), Expect = 3e-19
Identities = 67/243 (27%), Positives = 122/243 (50%), Gaps = 12/243 (4%)
Frame = +1
Query: 103 RGLCYPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTG 282
+GL PPGP P++G+++++ K HL SQ+YG++L +R+GS VVV++G
Sbjct: 35 KGLKNPPGPWDWPLIGHMLTL------GKNPHLALSRMSQQYGDVLQIRIGSTPVVVLSG 88
Query: 283 IELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGY- 453
++ I++ V + F+GRPD + +T+ S G+ + GP W RR LK+F
Sbjct: 89 LDTIRQALVRQGDDFKGRPDLYTFTLISNGQSMSFSPDSGPVWAARRRLAQNGLKSFSIA 148
Query: 454 ------NSRFMNVYIGEECEALVQLRFADAGEPILVNQMFH--ITIVNILWRLVAGKRYD 609
S ++ ++ +E E L+ P N + +++ N++ + G+RYD
Sbjct: 149 SDPASSTSCYLEEHVSKEAEVLISTLQELMAGPGHFNPYRYVVVSVTNVICAICFGRRYD 208
Query: 610 LXDQRLKKLCNLVMRLFKLXDMSGGILNFLPFLXHF-IPRLIGFTELQXIHNALHQYLRE 786
Q L L NL ++ SG +F+P L + P L F +L + + ++++
Sbjct: 209 HNHQELLSLVNLNNNFGEVVG-SGNPADFIPILRYLPNPSLNAFKDL---NEKFYSFMQK 264
Query: 787 IIK 795
++K
Sbjct: 265 MVK 267
>AC023172-1|AAF32444.1| 491|Homo sapiens CYP2B6 protein.
Length = 491
Score = 94.7 bits (225), Expect = 3e-19
Identities = 64/204 (31%), Positives = 101/204 (49%), Gaps = 4/204 (1%)
Frame = +1
Query: 118 PPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIK 297
PPGP PLP++GNL+ + R+ + + +KYG++ + LG VV++ G+E I+
Sbjct: 31 PPGPRPLPLLGNLLQM---DRRGLLKSFL--RFREKYGDVFTVHLGPRPVVMLCGVEAIR 85
Query: 298 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 471
E V E F GR G + F + G++F++G W RRF + +++FG R +
Sbjct: 86 EALVDKAEAFSGR--GKIAMVDPFFRGYGVIFANGNRWKVLRRFSVTTMRDFGMGKRSVE 143
Query: 472 VYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCNLVM 651
I EE + L++ G + +F NI+ +V GKR+ DQ K+ NL
Sbjct: 144 ERIQEEAQCLIEELRKSKGALMDPTFLFQSITANIICSIVFGKRFHYQDQEFLKMLNLFY 203
Query: 652 RLFKLXDMSGGIL--NFLPFLXHF 717
+ F L G L F FL +F
Sbjct: 204 QTFSLISSVFGQLFELFSGFLKYF 227
>X04300-1|CAA27843.1| 512|Homo sapiens P-450 c protein.
Length = 512
Score = 94.3 bits (224), Expect = 5e-19
Identities = 67/243 (27%), Positives = 122/243 (50%), Gaps = 12/243 (4%)
Frame = +1
Query: 103 RGLCYPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTG 282
+GL PPGP P++G+++++ K HL SQ+YG++L +R+GS VVV++G
Sbjct: 35 KGLKNPPGPWGWPLIGHMLTL------GKNPHLALSRMSQQYGDVLQIRIGSTPVVVLSG 88
Query: 283 IELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGY- 453
++ I++ V + F+GRPD + +T+ S G+ + GP W RR LK+F
Sbjct: 89 LDTIRQALVRQGDDFKGRPDLYTFTLISNGQSMSFSPDSGPVWAARRRLAQNGLKSFSIA 148
Query: 454 ------NSRFMNVYIGEECEALVQLRFADAGEPILVNQMFH--ITIVNILWRLVAGKRYD 609
S ++ ++ +E E L+ P N + +++ N++ + G+RYD
Sbjct: 149 SDPASSTSCYLEEHVSKEAEVLISTLQELMAGPGHFNPYRYVVVSVTNVICAICFGRRYD 208
Query: 610 LXDQRLKKLCNLVMRLFKLXDMSGGILNFLPFLXHF-IPRLIGFTELQXIHNALHQYLRE 786
Q L L NL ++ SG +F+P L + P L F +L + + ++++
Sbjct: 209 HNHQELLSLVNLNNNFGEVVG-SGNPADFIPILRYLPNPSLNAFKDL---NEKFYSFMQK 264
Query: 787 IIK 795
++K
Sbjct: 265 MVK 267
>X02612-1|CAA26458.1| 512|Homo sapiens cytochrome P(1)-450 protein.
Length = 512
Score = 94.3 bits (224), Expect = 5e-19
Identities = 67/243 (27%), Positives = 122/243 (50%), Gaps = 12/243 (4%)
Frame = +1
Query: 103 RGLCYPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTG 282
+GL PPGP P++G+++++ K HL SQ+YG++L +R+GS VVV++G
Sbjct: 35 KGLKNPPGPWGWPLIGHMLTL------GKNPHLALSRMSQQYGDVLQIRIGSTPVVVLSG 88
Query: 283 IELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGY- 453
++ I++ V + F+GRPD + +T+ S G+ + GP W RR LK+F
Sbjct: 89 LDTIRQALVRQGDDFKGRPDLYTFTLISNGQSMSFSPDSGPVWAARRRLAQNGLKSFSIA 148
Query: 454 ------NSRFMNVYIGEECEALVQLRFADAGEPILVNQMFH--ITIVNILWRLVAGKRYD 609
S ++ ++ +E E L+ P N + +++ N++ + G+RYD
Sbjct: 149 SDPASSTSCYLEEHVSKEAEVLISTLQELMAGPGHFNPYRYVVVSVTNVICAICFGRRYD 208
Query: 610 LXDQRLKKLCNLVMRLFKLXDMSGGILNFLPFLXHF-IPRLIGFTELQXIHNALHQYLRE 786
Q L L NL ++ SG +F+P L + P L F +L + + ++++
Sbjct: 209 HNHQELLSLVNLNNNFGEVVG-SGNPADFIPILRYLPNPSLNAFKDL---NEKFYSFMQK 264
Query: 787 IIK 795
++K
Sbjct: 265 MVK 267
>EF094025-1|ABK41999.1| 512|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 1 protein.
Length = 512
Score = 94.3 bits (224), Expect = 5e-19
Identities = 67/243 (27%), Positives = 122/243 (50%), Gaps = 12/243 (4%)
Frame = +1
Query: 103 RGLCYPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTG 282
+GL PPGP P++G+++++ K HL SQ+YG++L +R+GS VVV++G
Sbjct: 35 KGLKNPPGPWGWPLIGHMLTL------GKNPHLALSRMSQQYGDVLQIRIGSTPVVVLSG 88
Query: 283 IELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGY- 453
++ I++ V + F+GRPD + +T+ S G+ + GP W RR LK+F
Sbjct: 89 LDTIRQALVRQGDDFKGRPDLYTFTLISNGQSMSFSPDSGPVWAARRRLAQNGLKSFSIA 148
Query: 454 ------NSRFMNVYIGEECEALVQLRFADAGEPILVNQMFH--ITIVNILWRLVAGKRYD 609
S ++ ++ +E E L+ P N + +++ N++ + G+RYD
Sbjct: 149 SDPASSTSCYLEEHVSKEAEVLISTLQELMAGPGHFNPYRYVVVSVTNVICAICFGRRYD 208
Query: 610 LXDQRLKKLCNLVMRLFKLXDMSGGILNFLPFLXHF-IPRLIGFTELQXIHNALHQYLRE 786
Q L L NL ++ SG +F+P L + P L F +L + + ++++
Sbjct: 209 HNHQELLSLVNLNNNFGEVVG-SGNPADFIPILRYLPNPSLNAFKDL---NEKFYSFMQK 264
Query: 787 IIK 795
++K
Sbjct: 265 MVK 267
>BC023019-1|AAH23019.1| 512|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 1 protein.
Length = 512
Score = 94.3 bits (224), Expect = 5e-19
Identities = 67/243 (27%), Positives = 122/243 (50%), Gaps = 12/243 (4%)
Frame = +1
Query: 103 RGLCYPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTG 282
+GL PPGP P++G+++++ K HL SQ+YG++L +R+GS VVV++G
Sbjct: 35 KGLKNPPGPWGWPLIGHMLTL------GKNPHLALSRMSQQYGDVLQIRIGSTPVVVLSG 88
Query: 283 IELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGY- 453
++ I++ V + F+GRPD + +T+ S G+ + GP W RR LK+F
Sbjct: 89 LDTIRQALVRQGDDFKGRPDLYTFTLISNGQSMSFSPDSGPVWAARRRLAQNGLKSFSIA 148
Query: 454 ------NSRFMNVYIGEECEALVQLRFADAGEPILVNQMFH--ITIVNILWRLVAGKRYD 609
S ++ ++ +E E L+ P N + +++ N++ + G+RYD
Sbjct: 149 SDPASSTSCYLEEHVSKEAEVLISTLQELMAGPGHFNPYRYVVVSVTNVICAICFGRRYD 208
Query: 610 LXDQRLKKLCNLVMRLFKLXDMSGGILNFLPFLXHF-IPRLIGFTELQXIHNALHQYLRE 786
Q L L NL ++ SG +F+P L + P L F +L + + ++++
Sbjct: 209 HNHQELLSLVNLNNNFGEVVG-SGNPADFIPILRYLPNPSLNAFKDL---NEKFYSFMQK 264
Query: 787 IIK 795
++K
Sbjct: 265 MVK 267
>AF253322-1|AAK25727.1| 512|Homo sapiens cytochrome P450 protein.
Length = 512
Score = 94.3 bits (224), Expect = 5e-19
Identities = 67/243 (27%), Positives = 122/243 (50%), Gaps = 12/243 (4%)
Frame = +1
Query: 103 RGLCYPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTG 282
+GL PPGP P++G+++++ K HL SQ+YG++L +R+GS VVV++G
Sbjct: 35 KGLKNPPGPWGWPLIGHMLTL------GKNPHLALSRMSQQYGDVLQIRIGSTPVVVLSG 88
Query: 283 IELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGY- 453
++ I++ V + F+GRPD + +T+ S G+ + GP W RR LK+F
Sbjct: 89 LDTIRQALVRQGDDFKGRPDLYTFTLISNGQSMSFSPDSGPVWAARRRLAQNGLKSFSIA 148
Query: 454 ------NSRFMNVYIGEECEALVQLRFADAGEPILVNQMFH--ITIVNILWRLVAGKRYD 609
S ++ ++ +E E L+ P N + +++ N++ + G+RYD
Sbjct: 149 SDPASSTSCYLEEHVSKEAEVLISTLQELMAGPGHFNPYRYVVVSVTNVICAICFGRRYD 208
Query: 610 LXDQRLKKLCNLVMRLFKLXDMSGGILNFLPFLXHF-IPRLIGFTELQXIHNALHQYLRE 786
Q L L NL ++ SG +F+P L + P L F +L + + ++++
Sbjct: 209 HNHQELLSLVNLNNNFGEVVG-SGNPADFIPILRYLPNPSLNAFKDL---NEKFYSFMQK 264
Query: 787 IIK 795
++K
Sbjct: 265 MVK 267
>K03191-1|AAA52139.1| 512|Homo sapiens CYP1A1 protein.
Length = 512
Score = 93.9 bits (223), Expect = 6e-19
Identities = 67/243 (27%), Positives = 121/243 (49%), Gaps = 12/243 (4%)
Frame = +1
Query: 103 RGLCYPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTG 282
+GL PPGP P++G+++++ K HL SQ+YG++L +R+GS VVV++G
Sbjct: 35 KGLKNPPGPWGWPLIGHMLTL------GKNPHLALSRMSQQYGDVLQIRIGSTPVVVLSG 88
Query: 283 IELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGY- 453
++ I++ V + F+GRPD + +T+ S G+ + GP W RR LK+F
Sbjct: 89 LDTIRQALVRQGDDFKGRPDLYTFTLISNGQSMSFSPDSGPVWAARRRLAQNGLKSFSIA 148
Query: 454 ------NSRFMNVYIGEECEALVQLRFADAGEPILVNQMFH--ITIVNILWRLVAGKRYD 609
S ++ ++ +E E L+ P N + +++ N++ + G+RYD
Sbjct: 149 SDPASSTSCYLEEHVSKEAEVLISTLQELMAGPGHFNPYRYVVVSVTNVICAICFGRRYD 208
Query: 610 LXDQRLKKLCNLVMRLFKLXDMSGGILNFLPFLXHF-IPRLIGFTELQXIHNALHQYLRE 786
Q L L NL ++ SG F+P L + P L F +L + + ++++
Sbjct: 209 HNHQELLSLVNLNNNFGEVVG-SGNPAEFIPILRYLPNPSLNAFKDL---NEKFYSFMQK 264
Query: 787 IIK 795
++K
Sbjct: 265 MVK 267
>AY871801-1|AAX62803.1| 483|Homo sapiens cytochrome P450 family 1
subfamily A polypeptide 1 protein.
Length = 483
Score = 93.9 bits (223), Expect = 6e-19
Identities = 67/243 (27%), Positives = 122/243 (50%), Gaps = 12/243 (4%)
Frame = +1
Query: 103 RGLCYPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTG 282
+GL PPGP P++G+++++ K HL SQ+YG++L +R+GS VVV++G
Sbjct: 35 KGLENPPGPWGWPLIGHMLTL------GKNPHLALSRMSQQYGDVLQIRIGSTPVVVLSG 88
Query: 283 IELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGY- 453
++ I++ V + F+GRPD + +T+ S G+ + GP W RR LK+F
Sbjct: 89 LDTIRQALVRQGDDFKGRPDLYTFTLISNGQSMSFSPDSGPVWAARRRLAQNGLKSFSIA 148
Query: 454 ------NSRFMNVYIGEECEALVQLRFADAGEPILVNQMFH--ITIVNILWRLVAGKRYD 609
S ++ ++ +E E L+ P N + +++ N++ + G+RYD
Sbjct: 149 SDPASSTSCYLEEHVSKEAEVLISTLQELMAGPGHFNPYRYVVVSVTNVICAICFGRRYD 208
Query: 610 LXDQRLKKLCNLVMRLFKLXDMSGGILNFLPFLXHF-IPRLIGFTELQXIHNALHQYLRE 786
Q L L NL ++ SG +F+P L + P L F +L + + ++++
Sbjct: 209 HNHQELLSLVNLNNNFGEVVG-SGNPADFIPILRYLPNPSLNAFKDL---NEKFYSFMQK 264
Query: 787 IIK 795
++K
Sbjct: 265 MVK 267
>DQ282158-1|ABB77906.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 93.1 bits (221), Expect = 1e-18
Identities = 65/223 (29%), Positives = 107/223 (47%), Gaps = 6/223 (2%)
Frame = +1
Query: 85 IISRRHRGLC-YPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSI 261
++ RR R YPPGP PLP +GNL+ V +++ + C + +++G++ L+L
Sbjct: 22 LMHRRQRWAARYPPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWT 76
Query: 262 NVVVVTGIELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSD--GPTWHRTRRFVL 429
VVV+ G+ ++E V++ E RP + FG + VF GP W RRF +
Sbjct: 77 PVVVLNGLAAVREALVTHGEDTADRPPVPIIQILGFGPRSQGVFLARYGPAWREQRRFSV 136
Query: 430 KYLKNFGYNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYD 609
L+N G + + ++ EE L +G P N + + N++ L G+R++
Sbjct: 137 STLRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFE 196
Query: 610 LXDQRLKKLCNLVMR-LFKLXDMSGGILNFLPFLXHFIPRLIG 735
D R +L +L L + +LN +P L H IP L G
Sbjct: 197 YDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLH-IPALAG 238
>DQ282157-1|ABB77905.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 93.1 bits (221), Expect = 1e-18
Identities = 65/223 (29%), Positives = 107/223 (47%), Gaps = 6/223 (2%)
Frame = +1
Query: 85 IISRRHRGLC-YPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSI 261
++ RR R YPPGP PLP +GNL+ V +++ + C + +++G++ L+L
Sbjct: 22 LMHRRQRWAARYPPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWT 76
Query: 262 NVVVVTGIELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSD--GPTWHRTRRFVL 429
VVV+ G+ ++E V++ E RP + FG + VF GP W RRF +
Sbjct: 77 PVVVLNGLAAVREALVTHGEDTADRPPVPIIQILGFGPRSQGVFLARYGPAWREQRRFSV 136
Query: 430 KYLKNFGYNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYD 609
L+N G + + ++ EE L +G P N + + N++ L G+R++
Sbjct: 137 STLRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFE 196
Query: 610 LXDQRLKKLCNLVMR-LFKLXDMSGGILNFLPFLXHFIPRLIG 735
D R +L +L L + +LN +P L H IP L G
Sbjct: 197 YDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLH-IPALAG 238
>DQ282153-1|ABB77901.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 93.1 bits (221), Expect = 1e-18
Identities = 65/223 (29%), Positives = 107/223 (47%), Gaps = 6/223 (2%)
Frame = +1
Query: 85 IISRRHRGLC-YPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSI 261
++ RR R YPPGP PLP +GNL+ V +++ + C + +++G++ L+L
Sbjct: 22 LMHRRQRWAARYPPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWT 76
Query: 262 NVVVVTGIELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSD--GPTWHRTRRFVL 429
VVV+ G+ ++E V++ E RP + FG + VF GP W RRF +
Sbjct: 77 PVVVLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSI 136
Query: 430 KYLKNFGYNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYD 609
L+N G + + ++ EE L +G P N + + N++ L G+R++
Sbjct: 137 STLRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFE 196
Query: 610 LXDQRLKKLCNLVMR-LFKLXDMSGGILNFLPFLXHFIPRLIG 735
D R +L +L L + +LN +P L H IP L G
Sbjct: 197 YDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLH-IPALAG 238
>X08006-1|CAA30807.1| 497|Homo sapiens cytochrome P450 db1 protein.
Length = 497
Score = 92.7 bits (220), Expect = 1e-18
Identities = 65/223 (29%), Positives = 107/223 (47%), Gaps = 6/223 (2%)
Frame = +1
Query: 85 IISRRHRGLC-YPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSI 261
++ RR R YPPGP PLP +GNL+ V +++ + C + +++G++ L+L
Sbjct: 22 LMHRRQRWAARYPPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWT 76
Query: 262 NVVVVTGIELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSD--GPTWHRTRRFVL 429
VVV+ G+ ++E V++ E RP + FG + VF GP W RRF +
Sbjct: 77 PVVVLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSV 136
Query: 430 KYLKNFGYNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYD 609
L+N G + + ++ EE L +G P N + + N++ L G+R++
Sbjct: 137 STLRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFE 196
Query: 610 LXDQRLKKLCNLVMR-LFKLXDMSGGILNFLPFLXHFIPRLIG 735
D R +L +L L + +LN +P L H IP L G
Sbjct: 197 YDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLH-IPALAG 238
>M33388-1|AAA53500.1| 497|Homo sapiens cytochrome P450 IID6
protein.
Length = 497
Score = 92.7 bits (220), Expect = 1e-18
Identities = 65/223 (29%), Positives = 107/223 (47%), Gaps = 6/223 (2%)
Frame = +1
Query: 85 IISRRHRGLC-YPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSI 261
++ RR R YPPGP PLP +GNL+ V +++ + C + +++G++ L+L
Sbjct: 22 LMHRRQRWAARYPPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWT 76
Query: 262 NVVVVTGIELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSD--GPTWHRTRRFVL 429
VVV+ G+ ++E V++ E RP + FG + VF GP W RRF +
Sbjct: 77 PVVVLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSV 136
Query: 430 KYLKNFGYNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYD 609
L+N G + + ++ EE L +G P N + + N++ L G+R++
Sbjct: 137 STLRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFE 196
Query: 610 LXDQRLKKLCNLVMR-LFKLXDMSGGILNFLPFLXHFIPRLIG 735
D R +L +L L + +LN +P L H IP L G
Sbjct: 197 YDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLH-IPALAG 238
>M20403-1|AAA52153.1| 497|Homo sapiens CYP2D protein.
Length = 497
Score = 92.7 bits (220), Expect = 1e-18
Identities = 65/223 (29%), Positives = 107/223 (47%), Gaps = 6/223 (2%)
Frame = +1
Query: 85 IISRRHRGLC-YPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSI 261
++ RR R YPPGP PLP +GNL+ V +++ + C + +++G++ L+L
Sbjct: 22 LMHRRQRWAARYPPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWT 76
Query: 262 NVVVVTGIELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSD--GPTWHRTRRFVL 429
VVV+ G+ ++E V++ E RP + FG + VF GP W RRF +
Sbjct: 77 PVVVLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSV 136
Query: 430 KYLKNFGYNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYD 609
L+N G + + ++ EE L +G P N + + N++ L G+R++
Sbjct: 137 STLRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFE 196
Query: 610 LXDQRLKKLCNLVMR-LFKLXDMSGGILNFLPFLXHFIPRLIG 735
D R +L +L L + +LN +P L H IP L G
Sbjct: 197 YDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLH-IPALAG 238
>DQ282160-1|ABB77908.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 92.7 bits (220), Expect = 1e-18
Identities = 65/223 (29%), Positives = 107/223 (47%), Gaps = 6/223 (2%)
Frame = +1
Query: 85 IISRRHRGLC-YPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSI 261
++ RR R YPPGP PLP +GNL+ V +++ + C + +++G++ L+L
Sbjct: 22 LMHRRQRWAARYPPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWT 76
Query: 262 NVVVVTGIELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSD--GPTWHRTRRFVL 429
VVV+ G+ ++E V++ E RP + FG + VF GP W RRF +
Sbjct: 77 PVVVLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSV 136
Query: 430 KYLKNFGYNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYD 609
L+N G + + ++ EE L +G P N + + N++ L G+R++
Sbjct: 137 STLRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFE 196
Query: 610 LXDQRLKKLCNLVMR-LFKLXDMSGGILNFLPFLXHFIPRLIG 735
D R +L +L L + +LN +P L H IP L G
Sbjct: 197 YDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLH-IPALAG 238
>DQ282159-1|ABB77907.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 92.7 bits (220), Expect = 1e-18
Identities = 65/223 (29%), Positives = 107/223 (47%), Gaps = 6/223 (2%)
Frame = +1
Query: 85 IISRRHRGLC-YPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSI 261
++ RR R YPPGP PLP +GNL+ V +++ + C + +++G++ L+L
Sbjct: 22 LMHRRQRWAARYPPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWT 76
Query: 262 NVVVVTGIELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSD--GPTWHRTRRFVL 429
VVV+ G+ ++E V++ E RP + FG + VF GP W RRF +
Sbjct: 77 PVVVLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSV 136
Query: 430 KYLKNFGYNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYD 609
L+N G + + ++ EE L +G P N + + N++ L G+R++
Sbjct: 137 STLRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFE 196
Query: 610 LXDQRLKKLCNLVMR-LFKLXDMSGGILNFLPFLXHFIPRLIG 735
D R +L +L L + +LN +P L H IP L G
Sbjct: 197 YDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLH-IPALAG 238
>DQ282156-1|ABB77904.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 92.7 bits (220), Expect = 1e-18
Identities = 65/223 (29%), Positives = 107/223 (47%), Gaps = 6/223 (2%)
Frame = +1
Query: 85 IISRRHRGLC-YPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSI 261
++ RR R YPPGP PLP +GNL+ V +++ + C + +++G++ L+L
Sbjct: 22 LMHRRQRWAARYPPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWT 76
Query: 262 NVVVVTGIELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSD--GPTWHRTRRFVL 429
VVV+ G+ ++E V++ E RP + FG + VF GP W RRF +
Sbjct: 77 PVVVLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSV 136
Query: 430 KYLKNFGYNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYD 609
L+N G + + ++ EE L +G P N + + N++ L G+R++
Sbjct: 137 STLRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFE 196
Query: 610 LXDQRLKKLCNLVMR-LFKLXDMSGGILNFLPFLXHFIPRLIG 735
D R +L +L L + +LN +P L H IP L G
Sbjct: 197 YDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLH-IPALAG 238
>DQ282151-1|ABB77899.1| 496|Homo sapiens cytochrome P450 2D6
protein.
Length = 496
Score = 92.7 bits (220), Expect = 1e-18
Identities = 65/223 (29%), Positives = 107/223 (47%), Gaps = 6/223 (2%)
Frame = +1
Query: 85 IISRRHRGLC-YPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSI 261
++ RR R YPPGP PLP +GNL+ V +++ + C + +++G++ L+L
Sbjct: 22 LMHRRQRWAARYPPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWT 76
Query: 262 NVVVVTGIELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSD--GPTWHRTRRFVL 429
VVV+ G+ ++E V++ E RP + FG + VF GP W RRF +
Sbjct: 77 PVVVLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSV 136
Query: 430 KYLKNFGYNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYD 609
L+N G + + ++ EE L +G P N + + N++ L G+R++
Sbjct: 137 STLRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFE 196
Query: 610 LXDQRLKKLCNLVMR-LFKLXDMSGGILNFLPFLXHFIPRLIG 735
D R +L +L L + +LN +P L H IP L G
Sbjct: 197 YDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLH-IPALAG 238
>DQ282147-1|ABB77898.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 92.7 bits (220), Expect = 1e-18
Identities = 65/223 (29%), Positives = 107/223 (47%), Gaps = 6/223 (2%)
Frame = +1
Query: 85 IISRRHRGLC-YPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSI 261
++ RR R YPPGP PLP +GNL+ V +++ + C + +++G++ L+L
Sbjct: 22 LMHRRQRWAARYPPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWT 76
Query: 262 NVVVVTGIELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSD--GPTWHRTRRFVL 429
VVV+ G+ ++E V++ E RP + FG + VF GP W RRF +
Sbjct: 77 PVVVLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSV 136
Query: 430 KYLKNFGYNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYD 609
L+N G + + ++ EE L +G P N + + N++ L G+R++
Sbjct: 137 STLRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFE 196
Query: 610 LXDQRLKKLCNLVMR-LFKLXDMSGGILNFLPFLXHFIPRLIG 735
D R +L +L L + +LN +P L H IP L G
Sbjct: 197 YDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLH-IPALAG 238
>DQ282146-1|ABB77897.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 92.7 bits (220), Expect = 1e-18
Identities = 65/223 (29%), Positives = 107/223 (47%), Gaps = 6/223 (2%)
Frame = +1
Query: 85 IISRRHRGLC-YPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSI 261
++ RR R YPPGP PLP +GNL+ V +++ + C + +++G++ L+L
Sbjct: 22 LMHRRQRWAARYPPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWT 76
Query: 262 NVVVVTGIELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSD--GPTWHRTRRFVL 429
VVV+ G+ ++E V++ E RP + FG + VF GP W RRF +
Sbjct: 77 PVVVLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSV 136
Query: 430 KYLKNFGYNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYD 609
L+N G + + ++ EE L +G P N + + N++ L G+R++
Sbjct: 137 STLRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFE 196
Query: 610 LXDQRLKKLCNLVMR-LFKLXDMSGGILNFLPFLXHFIPRLIG 735
D R +L +L L + +LN +P L H IP L G
Sbjct: 197 YDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLH-IPALAG 238
>DQ282145-1|ABB77896.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 92.7 bits (220), Expect = 1e-18
Identities = 65/223 (29%), Positives = 107/223 (47%), Gaps = 6/223 (2%)
Frame = +1
Query: 85 IISRRHRGLC-YPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSI 261
++ RR R YPPGP PLP +GNL+ V +++ + C + +++G++ L+L
Sbjct: 22 LMHRRQRWAARYPPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWT 76
Query: 262 NVVVVTGIELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSD--GPTWHRTRRFVL 429
VVV+ G+ ++E V++ E RP + FG + VF GP W RRF +
Sbjct: 77 PVVVLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSV 136
Query: 430 KYLKNFGYNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYD 609
L+N G + + ++ EE L +G P N + + N++ L G+R++
Sbjct: 137 STLRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFE 196
Query: 610 LXDQRLKKLCNLVMR-LFKLXDMSGGILNFLPFLXHFIPRLIG 735
D R +L +L L + +LN +P L H IP L G
Sbjct: 197 YDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLH-IPALAG 238
>DQ282144-1|ABB77895.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 92.7 bits (220), Expect = 1e-18
Identities = 65/223 (29%), Positives = 107/223 (47%), Gaps = 6/223 (2%)
Frame = +1
Query: 85 IISRRHRGLC-YPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSI 261
++ RR R YPPGP PLP +GNL+ V +++ + C + +++G++ L+L
Sbjct: 22 LMHRRQRWAARYPPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWT 76
Query: 262 NVVVVTGIELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSD--GPTWHRTRRFVL 429
VVV+ G+ ++E V++ E RP + FG + VF GP W RRF +
Sbjct: 77 PVVVLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSV 136
Query: 430 KYLKNFGYNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYD 609
L+N G + + ++ EE L +G P N + + N++ L G+R++
Sbjct: 137 STLRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFE 196
Query: 610 LXDQRLKKLCNLVMR-LFKLXDMSGGILNFLPFLXHFIPRLIG 735
D R +L +L L + +LN +P L H IP L G
Sbjct: 197 YDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLH-IPALAG 238
>BC126858-1|AAI26859.1| 497|Homo sapiens cytochrome P450, family 2,
subfamily D, polypeptide 6 protein.
Length = 497
Score = 92.7 bits (220), Expect = 1e-18
Identities = 65/223 (29%), Positives = 107/223 (47%), Gaps = 6/223 (2%)
Frame = +1
Query: 85 IISRRHRGLC-YPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSI 261
++ RR R YPPGP PLP +GNL+ V +++ + C + +++G++ L+L
Sbjct: 22 LMHRRQRWAARYPPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWT 76
Query: 262 NVVVVTGIELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSD--GPTWHRTRRFVL 429
VVV+ G+ ++E V++ E RP + FG + VF GP W RRF +
Sbjct: 77 PVVVLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSV 136
Query: 430 KYLKNFGYNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYD 609
L+N G + + ++ EE L +G P N + + N++ L G+R++
Sbjct: 137 STLRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFE 196
Query: 610 LXDQRLKKLCNLVMR-LFKLXDMSGGILNFLPFLXHFIPRLIG 735
D R +L +L L + +LN +P L H IP L G
Sbjct: 197 YDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLH-IPALAG 238
>BC106758-1|AAI06759.1| 497|Homo sapiens cytochrome P450, family 2,
subfamily D, polypeptide 6 protein.
Length = 497
Score = 92.7 bits (220), Expect = 1e-18
Identities = 65/223 (29%), Positives = 107/223 (47%), Gaps = 6/223 (2%)
Frame = +1
Query: 85 IISRRHRGLC-YPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSI 261
++ RR R YPPGP PLP +GNL+ V +++ + C + +++G++ L+L
Sbjct: 22 LMHRRQRWAARYPPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWT 76
Query: 262 NVVVVTGIELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSD--GPTWHRTRRFVL 429
VVV+ G+ ++E V++ E RP + FG + VF GP W RRF +
Sbjct: 77 PVVVLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSV 136
Query: 430 KYLKNFGYNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYD 609
L+N G + + ++ EE L +G P N + + N++ L G+R++
Sbjct: 137 STLRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFE 196
Query: 610 LXDQRLKKLCNLVMR-LFKLXDMSGGILNFLPFLXHFIPRLIG 735
D R +L +L L + +LN +P L H IP L G
Sbjct: 197 YDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLH-IPALAG 238
>BC075024-1|AAH75024.1| 497|Homo sapiens cytochrome P450, family 2,
subfamily D, polypeptide 6 protein.
Length = 497
Score = 92.7 bits (220), Expect = 1e-18
Identities = 65/223 (29%), Positives = 107/223 (47%), Gaps = 6/223 (2%)
Frame = +1
Query: 85 IISRRHRGLC-YPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSI 261
++ RR R YPPGP PLP +GNL+ V +++ + C + +++G++ L+L
Sbjct: 22 LMHRRQRWAARYPPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWT 76
Query: 262 NVVVVTGIELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSD--GPTWHRTRRFVL 429
VVV+ G+ ++E V++ E RP + FG + VF GP W RRF +
Sbjct: 77 PVVVLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSV 136
Query: 430 KYLKNFGYNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYD 609
L+N G + + ++ EE L +G P N + + N++ L G+R++
Sbjct: 137 STLRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFE 196
Query: 610 LXDQRLKKLCNLVMR-LFKLXDMSGGILNFLPFLXHFIPRLIG 735
D R +L +L L + +LN +P L H IP L G
Sbjct: 197 YDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLH-IPALAG 238
>BC075023-1|AAH75023.1| 497|Homo sapiens cytochrome P450, family 2,
subfamily D, polypeptide 6 protein.
Length = 497
Score = 92.7 bits (220), Expect = 1e-18
Identities = 65/223 (29%), Positives = 107/223 (47%), Gaps = 6/223 (2%)
Frame = +1
Query: 85 IISRRHRGLC-YPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSI 261
++ RR R YPPGP PLP +GNL+ V +++ + C + +++G++ L+L
Sbjct: 22 LMHRRQRWAARYPPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWT 76
Query: 262 NVVVVTGIELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSD--GPTWHRTRRFVL 429
VVV+ G+ ++E V++ E RP + FG + VF GP W RRF +
Sbjct: 77 PVVVLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSV 136
Query: 430 KYLKNFGYNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYD 609
L+N G + + ++ EE L +G P N + + N++ L G+R++
Sbjct: 137 STLRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFE 196
Query: 610 LXDQRLKKLCNLVMR-LFKLXDMSGGILNFLPFLXHFIPRLIG 735
D R +L +L L + +LN +P L H IP L G
Sbjct: 197 YDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLH-IPALAG 238
>BC067432-1|AAH67432.1| 497|Homo sapiens cytochrome P450, family 2,
subfamily D, polypeptide 6 protein.
Length = 497
Score = 92.7 bits (220), Expect = 1e-18
Identities = 65/223 (29%), Positives = 107/223 (47%), Gaps = 6/223 (2%)
Frame = +1
Query: 85 IISRRHRGLC-YPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSI 261
++ RR R YPPGP PLP +GNL+ V +++ + C + +++G++ L+L
Sbjct: 22 LMHRRQRWAARYPPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWT 76
Query: 262 NVVVVTGIELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSD--GPTWHRTRRFVL 429
VVV+ G+ ++E V++ E RP + FG + VF GP W RRF +
Sbjct: 77 PVVVLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSV 136
Query: 430 KYLKNFGYNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYD 609
L+N G + + ++ EE L +G P N + + N++ L G+R++
Sbjct: 137 STLRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFE 196
Query: 610 LXDQRLKKLCNLVMR-LFKLXDMSGGILNFLPFLXHFIPRLIG 735
D R +L +L L + +LN +P L H IP L G
Sbjct: 197 YDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLH-IPALAG 238
>AY545216-1|AAS55001.1| 497|Homo sapiens cytochrome P4502D6
protein.
Length = 497
Score = 92.7 bits (220), Expect = 1e-18
Identities = 65/223 (29%), Positives = 107/223 (47%), Gaps = 6/223 (2%)
Frame = +1
Query: 85 IISRRHRGLC-YPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSI 261
++ RR R YPPGP PLP +GNL+ V +++ + C + +++G++ L+L
Sbjct: 22 LMHRRQRWAARYPPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWT 76
Query: 262 NVVVVTGIELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSD--GPTWHRTRRFVL 429
VVV+ G+ ++E V++ E RP + FG + VF GP W RRF +
Sbjct: 77 PVVVLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSV 136
Query: 430 KYLKNFGYNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYD 609
L+N G + + ++ EE L +G P N + + N++ L G+R++
Sbjct: 137 STLRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFE 196
Query: 610 LXDQRLKKLCNLVMR-LFKLXDMSGGILNFLPFLXHFIPRLIG 735
D R +L +L L + +LN +P L H IP L G
Sbjct: 197 YDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLH-IPALAG 238
>AK223108-1|BAD96828.1| 512|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 1 variant protein.
Length = 512
Score = 91.9 bits (218), Expect = 2e-18
Identities = 66/243 (27%), Positives = 121/243 (49%), Gaps = 12/243 (4%)
Frame = +1
Query: 103 RGLCYPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTG 282
+GL PPGP P++G+++++ K HL SQ+YG++L +R+GS VVV++G
Sbjct: 35 KGLKNPPGPWDWPLIGHMLTL------GKNPHLALSRMSQQYGDVLQIRIGSTPVVVLSG 88
Query: 283 IELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGY- 453
++ I++ V + F+GRPD + +T+ S G+ + GP W RR LK+F
Sbjct: 89 LDTIRQALVRQGDDFKGRPDLYTFTLISNGQSMSFSPDSGPVWAARRRLAQNGLKSFSIA 148
Query: 454 ------NSRFMNVYIGEECEALVQLRFADAGEPILVNQMFH--ITIVNILWRLVAGKRYD 609
S ++ ++ + E L+ P N + +++ N++ + G+RYD
Sbjct: 149 SDPASSTSCYLEEHVSKGAEVLISTLQELMAGPGHFNPYRYVVVSVTNVICAICFGRRYD 208
Query: 610 LXDQRLKKLCNLVMRLFKLXDMSGGILNFLPFLXHF-IPRLIGFTELQXIHNALHQYLRE 786
Q L L NL ++ SG +F+P L + P L F +L + + ++++
Sbjct: 209 HNHQELLSLVNLNNNFGEVVG-SGNPADFIPILRYLPNPSLNAFKDL---NEKFYSFMQK 264
Query: 787 IIK 795
++K
Sbjct: 265 MVK 267
>DQ282154-1|ABB77902.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 91.5 bits (217), Expect = 3e-18
Identities = 62/212 (29%), Positives = 102/212 (48%), Gaps = 5/212 (2%)
Frame = +1
Query: 115 YPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELI 294
YPPGP PLP +GNL+ V +++ + C + +++G++ L+L VVV+ G+ +
Sbjct: 33 YPPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWTPVVVLNGLAAV 87
Query: 295 KE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSD--GPTWHRTRRFVLKYLKNFGYNSR 462
+E V++ E RP + FG + VF GP W RRF + L+N G +
Sbjct: 88 REALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKK 147
Query: 463 FMNVYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCN 642
+ ++ EE L +G P N + + N++ L G+R++ D R +L +
Sbjct: 148 SLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLD 207
Query: 643 LVMR-LFKLXDMSGGILNFLPFLXHFIPRLIG 735
L L + +LN +P L H IP L G
Sbjct: 208 LAQEGLKEESGFLREVLNAVPVLLH-IPALAG 238
>AF372573-1|AAL69652.1| 495|Homo sapiens cytochrome P450 2F1
protein.
Length = 495
Score = 91.5 bits (217), Expect = 3e-18
Identities = 63/203 (31%), Positives = 100/203 (49%), Gaps = 2/203 (0%)
Frame = +1
Query: 88 ISRRHRGLCYPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINV 267
+S R +G PPGP PL ++GNL+ + + L S++YG++ + LG V
Sbjct: 22 LSSRDKGKL-PPGPRPLSILGNLLLLCSQDMLTSLTKL-----SKEYGSMYTVHLGPRRV 75
Query: 268 VVVTGIELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLK 441
VV++G + +KE V E F GR D + +F K G+ FS G W R+F ++ L+
Sbjct: 76 VVLSGYQAVKEALVDQGEEFSGRGD--YPAFFNFTKGNGIAFSSGDRWKVLRQFSIQILR 133
Query: 442 NFGYNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQ 621
NFG R + I EE L+ GEP + ++ NI+ ++ G R+D D+
Sbjct: 134 NFGMGKRSIEERILEEGSFLLAELRKTEGEPFDPTFVLSRSVSNIICSVLFGSRFDYDDE 193
Query: 622 RLKKLCNLVMRLFKLXDMSGGIL 690
RL + L+ F++ G L
Sbjct: 194 RLLTIIRLINDNFQIMSSPWGEL 216
>DQ282155-1|ABB77903.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 91.1 bits (216), Expect = 4e-18
Identities = 64/223 (28%), Positives = 107/223 (47%), Gaps = 6/223 (2%)
Frame = +1
Query: 85 IISRRHRGLC-YPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSI 261
++ RR R YPPGP PLP +GNL+ V +++ + C + +++G++ L+L
Sbjct: 22 LMHRRQRWAARYPPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWT 76
Query: 262 NVVVVTGIELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSD--GPTWHRTRRFVL 429
VVV+ G+ ++E V++ E RP + FG + VF GP W RRF +
Sbjct: 77 PVVVLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSV 136
Query: 430 KYLKNFGYNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYD 609
L+N G + + ++ +E L +G P N + + N++ L G+R++
Sbjct: 137 STLRNLGLGKKSLEQWVTKEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFE 196
Query: 610 LXDQRLKKLCNLVMR-LFKLXDMSGGILNFLPFLXHFIPRLIG 735
D R +L +L L + +LN +P L H IP L G
Sbjct: 197 YDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLH-IPALAG 238
>J02906-1|AAA52156.1| 491|Homo sapiens CYP2F1 protein.
Length = 491
Score = 90.6 bits (215), Expect = 6e-18
Identities = 63/203 (31%), Positives = 100/203 (49%), Gaps = 2/203 (0%)
Frame = +1
Query: 88 ISRRHRGLCYPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINV 267
+S R +G PPGP PL ++GNL+ + + L S++YG++ + LG V
Sbjct: 22 LSSRDKGKL-PPGPRPLSILGNLLLLCSQDMLTSLTKL-----SKEYGSMYTVHLGPRRV 75
Query: 268 VVVTGIELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLK 441
VV++G + +KE V E F GR D + +F K G+ FS G W R+F ++ L+
Sbjct: 76 VVLSGYQAVKEALVDQGEEFSGRGD--YPAFFNFTKGNGIAFSSGDRWKVLRQFSIQILR 133
Query: 442 NFGYNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQ 621
NFG R + I EE L+ GEP + ++ NI+ ++ G R+D D+
Sbjct: 134 NFGMGKRSIEERILEEGSFLLADVRKTEGEPFDPTFVLSRSVSNIICSVLFGSRFDYDDE 193
Query: 622 RLKKLCNLVMRLFKLXDMSGGIL 690
RL + L+ F++ G L
Sbjct: 194 RLLTIIRLINDNFQIMSSPWGEL 216
>DQ282152-1|ABB77900.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 89.4 bits (212), Expect = 1e-17
Identities = 64/223 (28%), Positives = 106/223 (47%), Gaps = 6/223 (2%)
Frame = +1
Query: 85 IISRRHRGLC-YPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSI 261
++ RR R Y PGP PLP +GNL+ V +++ + C + +++G++ L+L
Sbjct: 22 LMHRRQRWAARYSPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWT 76
Query: 262 NVVVVTGIELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSD--GPTWHRTRRFVL 429
VVV+ G+ ++E V++ E RP + FG + VF GP W RRF +
Sbjct: 77 PVVVLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSV 136
Query: 430 KYLKNFGYNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYD 609
L+N G + + ++ EE L +G P N + + N++ L G+R++
Sbjct: 137 STLRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFE 196
Query: 610 LXDQRLKKLCNLVMR-LFKLXDMSGGILNFLPFLXHFIPRLIG 735
D R +L +L L + +LN +P L H IP L G
Sbjct: 197 YDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLH-IPALAG 238
>DQ211354-2|ABB01372.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 89.4 bits (212), Expect = 1e-17
Identities = 64/223 (28%), Positives = 106/223 (47%), Gaps = 6/223 (2%)
Frame = +1
Query: 85 IISRRHRGLC-YPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSI 261
++ RR R Y PGP PLP +GNL+ V +++ + C + +++G++ L+L
Sbjct: 22 LMHRRQRWAARYSPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWT 76
Query: 262 NVVVVTGIELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSD--GPTWHRTRRFVL 429
VVV+ G+ ++E V++ E RP + FG + VF GP W RRF +
Sbjct: 77 PVVVLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSV 136
Query: 430 KYLKNFGYNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYD 609
L+N G + + ++ EE L +G P N + + N++ L G+R++
Sbjct: 137 STLRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFE 196
Query: 610 LXDQRLKKLCNLVMR-LFKLXDMSGGILNFLPFLXHFIPRLIG 735
D R +L +L L + +LN +P L H IP L G
Sbjct: 197 YDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLH-IPALAG 238
>DQ211353-2|ABB01371.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 89.4 bits (212), Expect = 1e-17
Identities = 64/223 (28%), Positives = 106/223 (47%), Gaps = 6/223 (2%)
Frame = +1
Query: 85 IISRRHRGLC-YPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSI 261
++ RR R Y PGP PLP +GNL+ V +++ + C + +++G++ L+L
Sbjct: 22 LMHRRQRWAARYSPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWT 76
Query: 262 NVVVVTGIELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSD--GPTWHRTRRFVL 429
VVV+ G+ ++E V++ E RP + FG + VF GP W RRF +
Sbjct: 77 PVVVLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSV 136
Query: 430 KYLKNFGYNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYD 609
L+N G + + ++ EE L +G P N + + N++ L G+R++
Sbjct: 137 STLRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFE 196
Query: 610 LXDQRLKKLCNLVMR-LFKLXDMSGGILNFLPFLXHFIPRLIG 735
D R +L +L L + +LN +P L H IP L G
Sbjct: 197 YDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLH-IPALAG 238
>DQ211353-1|ABB01370.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 89.4 bits (212), Expect = 1e-17
Identities = 64/223 (28%), Positives = 106/223 (47%), Gaps = 6/223 (2%)
Frame = +1
Query: 85 IISRRHRGLC-YPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSI 261
++ RR R Y PGP PLP +GNL+ V +++ + C + +++G++ L+L
Sbjct: 22 LMHRRQRWAARYSPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWT 76
Query: 262 NVVVVTGIELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSD--GPTWHRTRRFVL 429
VVV+ G+ ++E V++ E RP + FG + VF GP W RRF +
Sbjct: 77 PVVVLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSV 136
Query: 430 KYLKNFGYNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYD 609
L+N G + + ++ EE L +G P N + + N++ L G+R++
Sbjct: 137 STLRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFE 196
Query: 610 LXDQRLKKLCNLVMR-LFKLXDMSGGILNFLPFLXHFIPRLIG 735
D R +L +L L + +LN +P L H IP L G
Sbjct: 197 YDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLH-IPALAG 238
>AY310359-1|AAQ76692.1| 484|Homo sapiens cytochrome P450 1A1
variant protein.
Length = 484
Score = 88.2 bits (209), Expect = 3e-17
Identities = 57/192 (29%), Positives = 98/192 (51%), Gaps = 11/192 (5%)
Frame = +1
Query: 103 RGLCYPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTG 282
+GL PPGP P++G+++++ K HL SQ+YG++L +R+GS VVV++G
Sbjct: 35 KGLKNPPGPWGWPLIGHMLTL------GKNPHLALSRMSQQYGDVLQIRIGSTPVVVLSG 88
Query: 283 IELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGY- 453
++ I++ V + F+GRPD + +T+ S G+ + GP W RR LK+F
Sbjct: 89 LDTIRQALVRQGDDFKGRPDLYTFTLISNGQSMSFSPDSGPVWAARRRLAQNGLKSFSIA 148
Query: 454 ------NSRFMNVYIGEECEALVQLRFADAGEPILVNQMFH--ITIVNILWRLVAGKRYD 609
S ++ ++ +E E L+ P N + +++ N++ + G+RYD
Sbjct: 149 SDPASSTSCYLEEHVSKEAEVLISTLQELMAGPGHFNPYRYVVVSVTNVICAICFGRRYD 208
Query: 610 LXDQRLKKLCNL 645
Q L L NL
Sbjct: 209 HNHQELLSLVNL 220
>AM236046-1|CAJ84703.1| 229|Homo sapiens cytochrome P450 1A1
protein.
Length = 229
Score = 88.2 bits (209), Expect = 3e-17
Identities = 57/192 (29%), Positives = 98/192 (51%), Gaps = 11/192 (5%)
Frame = +1
Query: 103 RGLCYPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTG 282
+GL PPGP P++G+++++ K HL SQ+YG++L +R+GS VVV++G
Sbjct: 35 KGLKNPPGPWGWPLIGHMLTL------GKNPHLALSRMSQQYGDVLQIRIGSTPVVVLSG 88
Query: 283 IELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGY- 453
++ I++ V + F+GRPD + +T+ S G+ + GP W RR LK+F
Sbjct: 89 LDTIRQALVRQGDDFKGRPDLYTFTLISNGQSMSFSPDSGPVWAARRRLAQNGLKSFSIA 148
Query: 454 ------NSRFMNVYIGEECEALVQLRFADAGEPILVNQMFH--ITIVNILWRLVAGKRYD 609
S ++ ++ +E E L+ P N + +++ N++ + G+RYD
Sbjct: 149 SDPASSTSCYLEEHVSKEAEVLISTLQELMAGPGHFNPYRYVVVSVTNVICAICFGRRYD 208
Query: 610 LXDQRLKKLCNL 645
Q L L NL
Sbjct: 209 HNHQELLSLVNL 220
>S46963-1|AAB23864.2| 477|Homo sapiens cytochrome P-450 protein.
Length = 477
Score = 87.0 bits (206), Expect = 7e-17
Identities = 61/204 (29%), Positives = 92/204 (45%), Gaps = 4/204 (1%)
Frame = +1
Query: 118 PPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIK 297
PPGPTPLPV+GN++ + + +L S+ YG + L G +VV+ G E +K
Sbjct: 17 PPGPTPLPVIGNILQIGIKDISKSLTNL-----SKVYGPVFTLYFGLKPIVVLHGYEAVK 71
Query: 298 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 471
E + E F GR G F + G+VFS+G W RRF L L+NFG R +
Sbjct: 72 EALIDLGEEFSGR--GIFPLAERANRGFGIVFSNGKKWKEIRRFSLMTLRNFGMGKRSIE 129
Query: 472 VYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCNLVM 651
+ EE LV+ P + N++ ++ KR+D DQ+ L +
Sbjct: 130 DRVQEEARCLVEELRKTKASPCDPTFILGCAPCNVICSIIFHKRFDYKDQQFLNLMEKLN 189
Query: 652 RLFKLXDMSGGIL--NFLPFLXHF 717
K+ + NF P + +F
Sbjct: 190 ENIKILSSPWIQICNNFSPIIDYF 213
>M21939-1|AAA52158.1| 485|Homo sapiens CYP2C protein.
Length = 485
Score = 87.0 bits (206), Expect = 7e-17
Identities = 61/204 (29%), Positives = 92/204 (45%), Gaps = 4/204 (1%)
Frame = +1
Query: 118 PPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIK 297
PPGPTPLPV+GN++ + + +L S+ YG + L G +VV+ G E +K
Sbjct: 25 PPGPTPLPVIGNILQIGIKDISKSLTNL-----SKVYGPVFTLYFGLKPIVVLHGYEAVK 79
Query: 298 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 471
E + E F GR G F + G+VFS+G W RRF L L+NFG R +
Sbjct: 80 EALIDLGEEFSGR--GIFPLAERANRGFGIVFSNGKKWKEIRRFSLMTLRNFGMGKRSIE 137
Query: 472 VYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCNLVM 651
+ EE LV+ P + N++ ++ KR+D DQ+ L +
Sbjct: 138 DRVQEEARCLVEELRKTKASPCDPTFILGCAPCNVICSIIFHKRFDYKDQQFLNLMEKLN 197
Query: 652 RLFKLXDMSGGIL--NFLPFLXHF 717
K+ + NF P + +F
Sbjct: 198 ENIKILSSPWIQICNNFSPIIDYF 221
>M15331-1|AAA52157.1| 485|Homo sapiens CYP2C protein.
Length = 485
Score = 87.0 bits (206), Expect = 7e-17
Identities = 61/204 (29%), Positives = 92/204 (45%), Gaps = 4/204 (1%)
Frame = +1
Query: 118 PPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIK 297
PPGPTPLPV+GN++ + + +L S+ YG + L G +VV+ G E +K
Sbjct: 25 PPGPTPLPVIGNILQIGIKDISKSLTNL-----SKVYGPVFTLYFGLKPIVVLHGYEAVK 79
Query: 298 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 471
E + E F GR G F + G+VFS+G W RRF L L+NFG R +
Sbjct: 80 EALIDLGEEFSGR--GIFPLAERANRGFGIVFSNGKKWKEIRRFSLMTLRNFGMGKRSIE 137
Query: 472 VYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCNLVM 651
+ EE LV+ P + N++ ++ KR+D DQ+ L +
Sbjct: 138 DRVQEEARCLVEELRKTKASPCDPTFILGCAPCNVICSIIFHKRFDYKDQQFLNLMEKLN 197
Query: 652 RLFKLXDMSGGIL--NFLPFLXHF 717
K+ + NF P + +F
Sbjct: 198 ENIKILSSPWIQICNNFSPIIDYF 221
>L16880-1|AAD13466.1| 273|Homo sapiens cytochrome P-450 2C protein.
Length = 273
Score = 87.0 bits (206), Expect = 7e-17
Identities = 61/204 (29%), Positives = 92/204 (45%), Gaps = 4/204 (1%)
Frame = +1
Query: 118 PPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIK 297
PPGPTPLPV+GN++ + + +L S+ YG + L G +VV+ G E +K
Sbjct: 30 PPGPTPLPVIGNILQIGIKDISKSLTNL-----SKVYGPVFTLYFGLKPIVVLHGYEAVK 84
Query: 298 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 471
E + E F GR G F + G+VFS+G W RRF L L+NFG R +
Sbjct: 85 EALIDLGEEFSGR--GIFPLAERANRGFGIVFSNGKKWKEIRRFSLMTLRNFGMGKRSIE 142
Query: 472 VYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCNLVM 651
+ EE LV+ P + N++ ++ KR+D DQ+ L +
Sbjct: 143 DRVQEEARCLVEELRKTKASPCDPTFILGCAPCNVICSIIFHKRFDYKDQQFLNLMEKLN 202
Query: 652 RLFKLXDMSGGIL--NFLPFLXHF 717
K+ + NF P + +F
Sbjct: 203 ENIKILSSPWIQICNNFSPIIDYF 226
>D00173-1|BAA00123.1| 487|Homo sapiens cytochrome P-450 protein.
Length = 487
Score = 87.0 bits (206), Expect = 7e-17
Identities = 61/204 (29%), Positives = 92/204 (45%), Gaps = 4/204 (1%)
Frame = +1
Query: 118 PPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIK 297
PPGPTPLPV+GN++ + + +L S+ YG + L G +VV+ G E +K
Sbjct: 27 PPGPTPLPVIGNILQIGIKDISKSLTNL-----SKVYGPVFTLYFGLKPIVVLHGYEAVK 81
Query: 298 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 471
E + E F GR G F + G+VFS+G W RRF L L+NFG R +
Sbjct: 82 EALIDLGEEFSGR--GIFPLAERANRGFGIVFSNGKKWKEIRRFSLMTLRNFGMGKRSIE 139
Query: 472 VYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCNLVM 651
+ EE LV+ P + N++ ++ KR+D DQ+ L +
Sbjct: 140 DRVQEEARCLVEELRKTKASPCDPTFILGCAPCNVICSIIFHKRFDYKDQQFLNLMEKLN 199
Query: 652 RLFKLXDMSGGIL--NFLPFLXHF 717
K+ + NF P + +F
Sbjct: 200 ENIKILSSPWIQICNNFSPIIDYF 223
>DQ282162-1|ABB77909.1| 500|Homo sapiens cytochrome P450 2D6
protein.
Length = 500
Score = 87.0 bits (206), Expect = 7e-17
Identities = 65/226 (28%), Positives = 107/226 (47%), Gaps = 9/226 (3%)
Frame = +1
Query: 85 IISRRHRGLC-YPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSI 261
++ RR R YPPGP PLP +GNL+ V +++ + C + +++G++ L+L
Sbjct: 22 LMHRRQRWAARYPPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWT 76
Query: 262 NVVVVTGIELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSD--GPTWHRTRRFVL 429
VVV+ G+ ++E V++ E RP + FG + VF GP W RRF +
Sbjct: 77 PVVVLNGLAAVREALVTHGEDTADRPPVPIIQILGFGPRSQGVFLARYGPAWREQRRFSV 136
Query: 430 KYLKNFGYNSRFMNVYIGEECEALVQLRFADAG---EPILVNQMFHITIVNILWRLVAGK 600
L+N G + + ++ EE L +G P N + + N++ L G+
Sbjct: 137 STLRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPFRPNGLLDKAVSNVIASLTCGR 196
Query: 601 RYDLXDQRLKKLCNLVMR-LFKLXDMSGGILNFLPFLXHFIPRLIG 735
R++ D R +L +L L + +LN +P L H IP L G
Sbjct: 197 RFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLH-IPALAG 241
>BC125054-1|AAI25055.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 9 protein.
Length = 490
Score = 87.0 bits (206), Expect = 7e-17
Identities = 61/204 (29%), Positives = 92/204 (45%), Gaps = 4/204 (1%)
Frame = +1
Query: 118 PPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIK 297
PPGPTPLPV+GN++ + + +L S+ YG + L G +VV+ G E +K
Sbjct: 30 PPGPTPLPVIGNILQIGIKDISKSLTNL-----SKVYGPVFTLYFGLKPIVVLHGYEAVK 84
Query: 298 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 471
E + E F GR G F + G+VFS+G W RRF L L+NFG R +
Sbjct: 85 EALIDLGEEFSGR--GIFPLAERANRGFGIVFSNGKKWKEIRRFSLMTLRNFGMGKRSIE 142
Query: 472 VYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCNLVM 651
+ EE LV+ P + N++ ++ KR+D DQ+ L +
Sbjct: 143 DRVQEEARCLVEELRKTKASPCDPTFILGCAPCNVICSIIFHKRFDYKDQQFLNLMEKLN 202
Query: 652 RLFKLXDMSGGIL--NFLPFLXHF 717
K+ + NF P + +F
Sbjct: 203 ENIKILSSPWIQICNNFSPIIDYF 226
>AY702706-1|AAT94065.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 9 protein.
Length = 490
Score = 87.0 bits (206), Expect = 7e-17
Identities = 61/204 (29%), Positives = 92/204 (45%), Gaps = 4/204 (1%)
Frame = +1
Query: 118 PPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIK 297
PPGPTPLPV+GN++ + + +L S+ YG + L G +VV+ G E +K
Sbjct: 30 PPGPTPLPVIGNILQIGIKDISKSLTNL-----SKVYGPVFTLYFGLKPIVVLHGYEAVK 84
Query: 298 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 471
E + E F GR G F + G+VFS+G W RRF L L+NFG R +
Sbjct: 85 EALIDLGEEFSGR--GIFPLAERANRGFGIVFSNGKKWKEIRRFSLMTLRNFGMGKRSIE 142
Query: 472 VYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCNLVM 651
+ EE LV+ P + N++ ++ KR+D DQ+ L +
Sbjct: 143 DRVQEEARCLVEELRKTKASPCDPTFILGCAPCNVICSIIFHKRFDYKDQQFLNLMEKLN 202
Query: 652 RLFKLXDMSGGIL--NFLPFLXHF 717
K+ + NF P + +F
Sbjct: 203 ENIKILSSPWIQICNNFSPIIDYF 226
>AY341248-1|AAP88931.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 9 protein.
Length = 490
Score = 87.0 bits (206), Expect = 7e-17
Identities = 61/204 (29%), Positives = 92/204 (45%), Gaps = 4/204 (1%)
Frame = +1
Query: 118 PPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIK 297
PPGPTPLPV+GN++ + + +L S+ YG + L G +VV+ G E +K
Sbjct: 30 PPGPTPLPVIGNILQIGIKDISKSLTNL-----SKVYGPVFTLYFGLKPIVVLHGYEAVK 84
Query: 298 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 471
E + E F GR G F + G+VFS+G W RRF L L+NFG R +
Sbjct: 85 EALIDLGEEFSGR--GIFPLAERANRGFGIVFSNGKKWKEIRRFSLMTLRNFGMGKRSIE 142
Query: 472 VYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCNLVM 651
+ EE LV+ P + N++ ++ KR+D DQ+ L +
Sbjct: 143 DRVQEEARCLVEELRKTKASPCDPTFILGCAPCNVICSIIFHKRFDYKDQQFLNLMEKLN 202
Query: 652 RLFKLXDMSGGIL--NFLPFLXHF 717
K+ + NF P + +F
Sbjct: 203 ENIKILSSPWIQICNNFSPIIDYF 226
>AL359672-1|CAH71303.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 9 protein.
Length = 490
Score = 87.0 bits (206), Expect = 7e-17
Identities = 61/204 (29%), Positives = 92/204 (45%), Gaps = 4/204 (1%)
Frame = +1
Query: 118 PPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIK 297
PPGPTPLPV+GN++ + + +L S+ YG + L G +VV+ G E +K
Sbjct: 30 PPGPTPLPVIGNILQIGIKDISKSLTNL-----SKVYGPVFTLYFGLKPIVVLHGYEAVK 84
Query: 298 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 471
E + E F GR G F + G+VFS+G W RRF L L+NFG R +
Sbjct: 85 EALIDLGEEFSGR--GIFPLAERANRGFGIVFSNGKKWKEIRRFSLMTLRNFGMGKRSIE 142
Query: 472 VYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCNLVM 651
+ EE LV+ P + N++ ++ KR+D DQ+ L +
Sbjct: 143 DRVQEEARCLVEELRKTKASPCDPTFILGCAPCNVICSIIFHKRFDYKDQQFLNLMEKLN 202
Query: 652 RLFKLXDMSGGIL--NFLPFLXHF 717
K+ + NF P + +F
Sbjct: 203 ENIKILSSPWIQICNNFSPIIDYF 226
>M21941-1|AAA52160.1| 480|Homo sapiens CYP2C protein.
Length = 480
Score = 86.2 bits (204), Expect = 1e-16
Identities = 61/205 (29%), Positives = 93/205 (45%), Gaps = 3/205 (1%)
Frame = +1
Query: 118 PPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIK 297
PPGPTPLP++GN++ + K C + ++S+ YG + + G +VV G E +K
Sbjct: 20 PPGPTPLPIIGNMLQI---DVKDICKS--FTNFSKVYGPVFTVYFGMNPIVVFHGYEAVK 74
Query: 298 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 471
E + N E F GR G + K LG++ S+G W RRF L L+NFG R +
Sbjct: 75 EALIDNGEEFSGR--GNSPISQRITKGLGIISSNGKRWKEIRRFSLTTLRNFGMGKRSIE 132
Query: 472 VYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCNLVM 651
+ EE LV+ P + N++ +V KR+D DQ+ L
Sbjct: 133 DRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQKFLTLMKRFN 192
Query: 652 RLFKLXDMSG-GILNFLPFLXHFIP 723
F++ + + N P L P
Sbjct: 193 ENFRILNSPWIQVCNNFPLLIDCFP 217
>M61854-1|AAB59426.1| 490|Homo sapiens cytochrome protein.
Length = 490
Score = 85.8 bits (203), Expect = 2e-16
Identities = 56/175 (32%), Positives = 83/175 (47%), Gaps = 2/175 (1%)
Frame = +1
Query: 118 PPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIK 297
PPGPTPLPV+GN++ + + +L S+ YG + L G +VV+ G E++K
Sbjct: 30 PPGPTPLPVIGNILQIDIKDVSKSLTNL-----SKIYGPVFTLYFGLERMVVLHGYEVVK 84
Query: 298 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 471
E + E F GR G F + G+VFS+G W RRF L L+NFG R +
Sbjct: 85 EALIDLGEEFSGR--GHFPLAERANRGFGIVFSNGKRWKEIRRFSLMTLRNFGMGKRSIE 142
Query: 472 VYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKL 636
+ EE LV+ P + N++ ++ KR+D DQ+ L
Sbjct: 143 DRVQEEARCLVEELRKTKASPCDPTFILGCAPCNVICSIIFQKRFDYKDQQFLNL 197
>AY796203-1|AAV41877.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 19 protein.
Length = 490
Score = 85.8 bits (203), Expect = 2e-16
Identities = 56/175 (32%), Positives = 83/175 (47%), Gaps = 2/175 (1%)
Frame = +1
Query: 118 PPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIK 297
PPGPTPLPV+GN++ + + +L S+ YG + L G +VV+ G E++K
Sbjct: 30 PPGPTPLPVIGNILQIDIKDVSKSLTNL-----SKIYGPVFTLYFGLERMVVLHGYEVVK 84
Query: 298 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 471
E + E F GR G F + G+VFS+G W RRF L L+NFG R +
Sbjct: 85 EALIDLGEEFSGR--GHFPLAERANRGFGIVFSNGKRWKEIRRFSLMTLRNFGMGKRSIE 142
Query: 472 VYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKL 636
+ EE LV+ P + N++ ++ KR+D DQ+ L
Sbjct: 143 DRVQEEARCLVEELRKTKASPCDPTFILGCAPCNVICSIIFQKRFDYKDQQFLNL 197
>AL583836-2|CAH74068.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 19 protein.
Length = 490
Score = 85.8 bits (203), Expect = 2e-16
Identities = 56/175 (32%), Positives = 83/175 (47%), Gaps = 2/175 (1%)
Frame = +1
Query: 118 PPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIK 297
PPGPTPLPV+GN++ + + +L S+ YG + L G +VV+ G E++K
Sbjct: 30 PPGPTPLPVIGNILQIDIKDVSKSLTNL-----SKIYGPVFTLYFGLERMVVLHGYEVVK 84
Query: 298 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 471
E + E F GR G F + G+VFS+G W RRF L L+NFG R +
Sbjct: 85 EALIDLGEEFSGR--GHFPLAERANRGFGIVFSNGKRWKEIRRFSLMTLRNFGMGKRSIE 142
Query: 472 VYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKL 636
+ EE LV+ P + N++ ++ KR+D DQ+ L
Sbjct: 143 DRVQEEARCLVEELRKTKASPCDPTFILGCAPCNVICSIIFQKRFDYKDQQFLNL 197
>AL133513-2|CAH73444.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 19 protein.
Length = 490
Score = 85.8 bits (203), Expect = 2e-16
Identities = 56/175 (32%), Positives = 83/175 (47%), Gaps = 2/175 (1%)
Frame = +1
Query: 118 PPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIK 297
PPGPTPLPV+GN++ + + +L S+ YG + L G +VV+ G E++K
Sbjct: 30 PPGPTPLPVIGNILQIDIKDVSKSLTNL-----SKIYGPVFTLYFGLERMVVLHGYEVVK 84
Query: 298 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 471
E + E F GR G F + G+VFS+G W RRF L L+NFG R +
Sbjct: 85 EALIDLGEEFSGR--GHFPLAERANRGFGIVFSNGKRWKEIRRFSLMTLRNFGMGKRSIE 142
Query: 472 VYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKL 636
+ EE LV+ P + N++ ++ KR+D DQ+ L
Sbjct: 143 DRVQEEARCLVEELRKTKASPCDPTFILGCAPCNVICSIIFQKRFDYKDQQFLNL 197
>Y00498-1|CAA68550.1| 490|Homo sapiens IIC2 protein.
Length = 490
Score = 85.4 bits (202), Expect = 2e-16
Identities = 61/205 (29%), Positives = 92/205 (44%), Gaps = 3/205 (1%)
Frame = +1
Query: 118 PPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIK 297
PPGPTPLP++GN++ + K C + ++S+ YG + + G +VV G E +K
Sbjct: 30 PPGPTPLPIIGNMLQI---DVKDICKS--FTNFSKVYGPVFTVYFGMNPIVVFHGYEAVK 84
Query: 298 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 471
E + N E F GR G + K LG++ S+G W RRF L L+NFG R +
Sbjct: 85 EALIDNGEEFSGR--GNSPISQRITKGLGIISSNGKRWKEIRRFSLTTLRNFGMGKRSIE 142
Query: 472 VYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCNLVM 651
+ EE LV+ P + N++ +V KR+D DQ L
Sbjct: 143 DRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLMKRFN 202
Query: 652 RLFKLXDMSG-GILNFLPFLXHFIP 723
F++ + + N P L P
Sbjct: 203 ENFRILNSPWIQVCNNFPLLIDCFP 227
>X13930-1|CAA32118.1| 494|Homo sapiens protein ( Human CYP2A4 mRNA
for P-450 IIA4 protein. ).
Length = 494
Score = 85.4 bits (202), Expect = 2e-16
Identities = 59/193 (30%), Positives = 90/193 (46%), Gaps = 2/193 (1%)
Frame = +1
Query: 118 PPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIK 297
PPGPTPLP +GN + + E + S++YG + + LG VVV+ G + ++
Sbjct: 34 PPGPTPLPFIGNYLQLNTEQMYNSLMKI-----SERYGPVFTIHLGPRRVVVLCGHDAVR 88
Query: 298 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 471
E V E F GR G T K G+VFS+G + RRF + L++FG R +
Sbjct: 89 EALVDQAEEFSGR--GEQATFDWVFKGYGVVFSNGERAKQLRRFSIATLRDFGVGKRGIE 146
Query: 472 VYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCNLVM 651
I EE L+ G I T+ N++ +V G R+D D+ L +++
Sbjct: 147 ERIQEEAGFLIDAHRGTGGANIDPTFFLSRTVSNVISSIVFGDRFDYKDKEFLSLLRMML 206
Query: 652 RLFKLXDMSGGIL 690
+F+ S G L
Sbjct: 207 GIFQFTSTSTGQL 219
>X13897-1|CAA32097.1| 489|Homo sapiens protein ( Human mRNA for
cytochrome P-450IIA. ).
Length = 489
Score = 85.4 bits (202), Expect = 2e-16
Identities = 61/201 (30%), Positives = 95/201 (47%), Gaps = 2/201 (0%)
Frame = +1
Query: 94 RRHRGLCYPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 273
R+++G PPGPTPLP +GN + + E + S++YG + + LG VVV
Sbjct: 22 RKNKGKL-PPGPTPLPFIGNYLQLNTEQMYNSLMKI-----SERYGPVFTIHLGPRRVVV 75
Query: 274 VTGIELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNF 447
+ G + ++E V E F GR G T K G+VFS+G + RRF + L++F
Sbjct: 76 LCGHDAVREALVDQAEEFSGR--GEQATFDWVFKGYGVVFSNGERAKQLRRFSIATLRDF 133
Query: 448 GYNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRL 627
G R + I EE L+ G I T+ N++ +V G R+D D+
Sbjct: 134 GVGKRGIEERIQEEAGFLIDALRGTGGANIDPTFFLSRTVSNVISSIVFGDRFDYKDKEF 193
Query: 628 KKLCNLVMRLFKLXDMSGGIL 690
L +++ +F+ S G L
Sbjct: 194 LSLLRMMLGIFQFTSTSTGQL 214
>M17398-1|AAA35740.1| 393|Homo sapiens protein ( Human cytochrome
P-450 1 mRNA, complete cds, clone Hp1-2. ).
Length = 393
Score = 85.4 bits (202), Expect = 2e-16
Identities = 61/205 (29%), Positives = 92/205 (44%), Gaps = 3/205 (1%)
Frame = +1
Query: 118 PPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIK 297
PPGPTPLP++GN++ + K C + ++S+ YG + + G +VV G E +K
Sbjct: 30 PPGPTPLPIIGNMLQI---DVKDICKS--FTNFSKVYGPVFTVYFGMNPIVVFHGYEAVK 84
Query: 298 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 471
E + N E F GR G + K LG++ S+G W RRF L L+NFG R +
Sbjct: 85 EALIDNGEEFSGR--GNSPISQRITKGLGIISSNGKRWKEIRRFSLTNLRNFGMGKRSIE 142
Query: 472 VYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCNLVM 651
+ EE LV+ P + N++ +V KR+D DQ L
Sbjct: 143 DRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLMKRFN 202
Query: 652 RLFKLXDMSG-GILNFLPFLXHFIP 723
F++ + + N P L P
Sbjct: 203 ENFRILNSPWIQVCNNFPLLIDCFP 227
>M17397-1|AAA35739.1| 490|Homo sapiens protein ( Human cytochrome
P-450 1 functional form mRNA, complete cds. ).
Length = 490
Score = 85.4 bits (202), Expect = 2e-16
Identities = 61/205 (29%), Positives = 92/205 (44%), Gaps = 3/205 (1%)
Frame = +1
Query: 118 PPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIK 297
PPGPTPLP++GN++ + K C + ++S+ YG + + G +VV G E +K
Sbjct: 30 PPGPTPLPIIGNMLQI---DVKDICKS--FTNFSKVYGPVFTVYFGMNPIVVFHGYEAVK 84
Query: 298 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 471
E + N E F GR G + K LG++ S+G W RRF L L+NFG R +
Sbjct: 85 EALIDNGEEFSGR--GNSPISQRITKGLGIISSNGKRWKEIRRFSLTNLRNFGMGKRSIE 142
Query: 472 VYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCNLVM 651
+ EE LV+ P + N++ +V KR+D DQ L
Sbjct: 143 DRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLMKRFN 202
Query: 652 RLFKLXDMSG-GILNFLPFLXHFIP 723
F++ + + N P L P
Sbjct: 203 ENFRILNSPWIQVCNNFPLLIDCFP 227
>BC096255-1|AAH96255.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 85.4 bits (202), Expect = 2e-16
Identities = 59/193 (30%), Positives = 90/193 (46%), Gaps = 2/193 (1%)
Frame = +1
Query: 118 PPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIK 297
PPGPTPLP +GN + + E + S++YG + + LG VVV+ G + ++
Sbjct: 34 PPGPTPLPFIGNYLQLNTEQMYNSLMKI-----SERYGPVFTIHLGPRRVVVLCGHDAVR 88
Query: 298 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 471
E V E F GR G T K G+VFS+G + RRF + L++FG R +
Sbjct: 89 EALVDQAEEFSGR--GEQATFDWVFKGYGVVFSNGERAKQLRRFSIATLRDFGVGKRGIE 146
Query: 472 VYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCNLVM 651
I EE L+ G I T+ N++ +V G R+D D+ L +++
Sbjct: 147 ERIQEEAGFLIDAHRGTGGANIDPTFFLSRTVSNVISSIVFGDRFDYKDKEFLSLLRMML 206
Query: 652 RLFKLXDMSGGIL 690
+F+ S G L
Sbjct: 207 GIFQFTSTSTGQL 219
>AY514490-1|AAR89907.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 8 protein.
Length = 490
Score = 85.4 bits (202), Expect = 2e-16
Identities = 61/205 (29%), Positives = 92/205 (44%), Gaps = 3/205 (1%)
Frame = +1
Query: 118 PPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIK 297
PPGPTPLP++GN++ + K C + ++S+ YG + + G +VV G E +K
Sbjct: 30 PPGPTPLPIIGNMLQI---DVKDICKS--FTNFSKVYGPVFTVYFGMNPIVVFHGYEAVK 84
Query: 298 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 471
E + N E F GR G + K LG++ S+G W RRF L L+NFG R +
Sbjct: 85 EALIDNGEEFSGR--GNSPISQRITKGLGIISSNGKRWKEIRRFSLTTLRNFGMGKRSIE 142
Query: 472 VYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCNLVM 651
+ EE LV+ P + N++ +V KR+D DQ L
Sbjct: 143 DRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLMKRFN 202
Query: 652 RLFKLXDMSG-GILNFLPFLXHFIP 723
F++ + + N P L P
Sbjct: 203 ENFRILNSPWIQVCNNFPLLIDCFP 227
>AY513608-1|AAR90939.1| 494|Homo sapiens cytochrome P450 2A13
variant 5 protein.
Length = 494
Score = 85.4 bits (202), Expect = 2e-16
Identities = 69/228 (30%), Positives = 103/228 (45%), Gaps = 5/228 (2%)
Frame = +1
Query: 94 RRHRGLCYPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 273
R+ RG PPGPTPLP +GN + + E + S++YG + + LG VVV
Sbjct: 27 RKSRGKL-PPGPTPLPFIGNYLQLNTEQMYNSLMKI-----SERYGPVFTIHLGPRRVVV 80
Query: 274 VTGIELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNF 447
+ G + +KE V E F GR G T K G+ FS+G + RRF + L+ F
Sbjct: 81 LCGHDAVKEALVDQAEEFSGR--GEQATFDWLFKGYGVAFSNGERAKQLRRFSIATLRGF 138
Query: 448 GYNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRL 627
G R + I EE L++ G I T+ N++ +V G R+D D+
Sbjct: 139 GVGKRGIEERIQEEAGFLIEALRGTHGANIDPTFFLSRTVSNVISSIVFGDRFDYEDKEF 198
Query: 628 KKLCNLVMRLFKLXDMSGGIL--NFLPFLXHFI-PRLIGFTELQXIHN 762
L +++ F+ S G L F + H P+ F ELQ + +
Sbjct: 199 LSLLRMMLGSFQFTATSTGQLYEMFSSVMKHLPGPQQQAFKELQGLED 246
>AL359672-5|CAH71307.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 8 protein.
Length = 490
Score = 85.4 bits (202), Expect = 2e-16
Identities = 61/205 (29%), Positives = 92/205 (44%), Gaps = 3/205 (1%)
Frame = +1
Query: 118 PPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIK 297
PPGPTPLP++GN++ + K C + ++S+ YG + + G +VV G E +K
Sbjct: 30 PPGPTPLPIIGNMLQI---DVKDICKS--FTNFSKVYGPVFTVYFGMNPIVVFHGYEAVK 84
Query: 298 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 471
E + N E F GR G + K LG++ S+G W RRF L L+NFG R +
Sbjct: 85 EALIDNGEEFSGR--GNSPISQRITKGLGIISSNGKRWKEIRRFSLTTLRNFGMGKRSIE 142
Query: 472 VYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCNLVM 651
+ EE LV+ P + N++ +V KR+D DQ L
Sbjct: 143 DRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLMKRFN 202
Query: 652 RLFKLXDMSG-GILNFLPFLXHFIP 723
F++ + + N P L P
Sbjct: 203 ENFRILNSPWIQVCNNFPLLIDCFP 227
>U22028-1|AAB40519.1| 494|Homo sapiens cytochrome P450 protein.
Length = 494
Score = 85.0 bits (201), Expect = 3e-16
Identities = 69/228 (30%), Positives = 102/228 (44%), Gaps = 5/228 (2%)
Frame = +1
Query: 94 RRHRGLCYPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 273
R+ RG PPGPTPLP +GN + + E + S++YG + + LG VVV
Sbjct: 27 RKSRGKL-PPGPTPLPFIGNYLQLNTEQMYNSLMKI-----SERYGPVFTIHLGPRRVVV 80
Query: 274 VTGIELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNF 447
+ G + +KE V E F GR G T K G+ FS+G + RRF + L+ F
Sbjct: 81 LCGHDAVKEALVDQAEEFSGR--GEQATFDWLFKGYGVAFSNGERAKQLRRFSIATLRGF 138
Query: 448 GYNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRL 627
G R + I EE L+ G I T+ N++ +V G R+D D+
Sbjct: 139 GVGKRGIEERIQEEAGFLIDALRGTHGANIDPTFFLSRTVSNVISSIVFGDRFDYEDKEF 198
Query: 628 KKLCNLVMRLFKLXDMSGGIL--NFLPFLXHFI-PRLIGFTELQXIHN 762
L +++ F+ S G L F + H P+ F ELQ + +
Sbjct: 199 LSLLRMMLGRFQFTGTSTGQLYEMFSSVMKHLPGPQQQAFKELQGLED 246
>BC020596-1|AAH20596.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 8 protein.
Length = 490
Score = 85.0 bits (201), Expect = 3e-16
Identities = 61/205 (29%), Positives = 92/205 (44%), Gaps = 3/205 (1%)
Frame = +1
Query: 118 PPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIK 297
PPGPTPLP++GN++ + K C + ++S+ YG + + G +VV G E +K
Sbjct: 30 PPGPTPLPIIGNMLQI---DVKDICKS--FTNFSKVYGPVFTVYFGMNPIVVFHGYESVK 84
Query: 298 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 471
E + N E F GR G + K LG++ S+G W RRF L L+NFG R +
Sbjct: 85 EALIDNGEEFSGR--GNSPISQRITKGLGIISSNGKRWKEIRRFSLTTLRNFGMGKRSIE 142
Query: 472 VYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCNLVM 651
+ EE LV+ P + N++ +V KR+D DQ L
Sbjct: 143 DRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLMKRFN 202
Query: 652 RLFKLXDMSG-GILNFLPFLXHFIP 723
F++ + + N P L P
Sbjct: 203 ENFRILNSPWIQVCNNFPLLIDCFP 227
>M33318-1|AAA52067.1| 494|Homo sapiens CYP2A protein.
Length = 494
Score = 84.6 bits (200), Expect = 4e-16
Identities = 59/193 (30%), Positives = 90/193 (46%), Gaps = 2/193 (1%)
Frame = +1
Query: 118 PPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIK 297
PPGPTPLP +GN + + E + S++YG + + LG VVV+ G + ++
Sbjct: 34 PPGPTPLPFIGNYLQLNTEQMYNSLMKI-----SERYGPVFTIHLGPRRVVVLCGHDAVR 88
Query: 298 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 471
E V E F GR G T K G+VFS+G + RRF + L++FG R +
Sbjct: 89 EALVDQAEEFSGR--GEQATFDWVFKGYGVVFSNGERAKQLRRFSIATLRDFGVGKRGIE 146
Query: 472 VYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCNLVM 651
I EE L+ G I T+ N++ +V G R+D D+ L +++
Sbjct: 147 ERIQEEAGFLIDALRGTGGANIDPTFFLSRTVSNVISSIVFGDRFDYKDKEFLSLLRMML 206
Query: 652 RLFKLXDMSGGIL 690
+F+ S G L
Sbjct: 207 GIFQFTSTSTGQL 219
>M21942-1|AAA52161.1| 462|Homo sapiens CYP2C protein.
Length = 462
Score = 84.6 bits (200), Expect = 4e-16
Identities = 61/205 (29%), Positives = 91/205 (44%), Gaps = 3/205 (1%)
Frame = +1
Query: 118 PPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIK 297
PPGPTPLP++GN++ + K C + ++S+ YG + + G +VV G E +K
Sbjct: 2 PPGPTPLPIIGNMLQI---DVKDICKS--FTNFSKVYGPVFTVYFGMNPIVVFHGYEAVK 56
Query: 298 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 471
E + N E F GR G + K LG++ S+G W RRF L L+NFG R +
Sbjct: 57 EALIDNGEEFSGR--GNSPISQRITKGLGIISSNGKRWKEIRRFSLTTLRNFGMGKRSIE 114
Query: 472 VYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCNLVM 651
+ EE LV P + N++ +V KR+D DQ L
Sbjct: 115 DRVQEEAHCLVDELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLMKRFN 174
Query: 652 RLFKLXDMSG-GILNFLPFLXHFIP 723
F++ + + N P L P
Sbjct: 175 ENFRILNSPWIQVCNNFPLLIDCFP 199
>BC096256-1|AAH96256.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 84.6 bits (200), Expect = 4e-16
Identities = 59/193 (30%), Positives = 90/193 (46%), Gaps = 2/193 (1%)
Frame = +1
Query: 118 PPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIK 297
PPGPTPLP +GN + + E + S++YG + + LG VVV+ G + ++
Sbjct: 34 PPGPTPLPFIGNYLQLNTEQMYNSLMKI-----SERYGPVFTIHLGPRRVVVLCGHDAVR 88
Query: 298 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 471
E V E F GR G T K G+VFS+G + RRF + L++FG R +
Sbjct: 89 EALVDQAEEFSGR--GEQATFDWVFKGYGVVFSNGERAKQLRRFSIATLRDFGVGKRGIE 146
Query: 472 VYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCNLVM 651
I EE L+ G I T+ N++ +V G R+D D+ L +++
Sbjct: 147 ERIQEEAGFLIDALRGTGGANIDPTFFLSRTVSNVISSIVFGDRFDYKDKEFLSLLRMML 206
Query: 652 RLFKLXDMSGGIL 690
+F+ S G L
Sbjct: 207 GIFQFTSTSTGQL 219
>BC096254-1|AAH96254.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 84.6 bits (200), Expect = 4e-16
Identities = 59/193 (30%), Positives = 90/193 (46%), Gaps = 2/193 (1%)
Frame = +1
Query: 118 PPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIK 297
PPGPTPLP +GN + + E + S++YG + + LG VVV+ G + ++
Sbjct: 34 PPGPTPLPFIGNYLQLNTEQMYNSLMKI-----SERYGPVFTIHLGPRRVVVLCGHDAVR 88
Query: 298 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 471
E V E F GR G T K G+VFS+G + RRF + L++FG R +
Sbjct: 89 EALVDQAEEFSGR--GEQATFDWVFKGYGVVFSNGERAKQLRRFSIATLRDFGVGKRGIE 146
Query: 472 VYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCNLVM 651
I EE L+ G I T+ N++ +V G R+D D+ L +++
Sbjct: 147 ERIQEEAGFLIDALRGTGGANIDPTFFLSRTVSNVISSIVFGDRFDYKDKEFLSLLRMML 206
Query: 652 RLFKLXDMSGGIL 690
+F+ S G L
Sbjct: 207 GIFQFTSTSTGQL 219
>BC096253-1|AAH96253.3| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 84.6 bits (200), Expect = 4e-16
Identities = 59/193 (30%), Positives = 90/193 (46%), Gaps = 2/193 (1%)
Frame = +1
Query: 118 PPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIK 297
PPGPTPLP +GN + + E + S++YG + + LG VVV+ G + ++
Sbjct: 34 PPGPTPLPFIGNYLQLNTEQMYNSLMKI-----SERYGPVFTIHLGPRRVVVLCGHDAVR 88
Query: 298 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 471
E V E F GR G T K G+VFS+G + RRF + L++FG R +
Sbjct: 89 EALVDQAEEFSGR--GEQATFDWVFKGYGVVFSNGERAKQLRRFSIATLRDFGVGKRGIE 146
Query: 472 VYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCNLVM 651
I EE L+ G I T+ N++ +V G R+D D+ L +++
Sbjct: 147 ERIQEEAGFLIDALRGTGGANIDPTFFLSRTVSNVISSIVFGDRFDYKDKEFLSLLRMML 206
Query: 652 RLFKLXDMSGGIL 690
+F+ S G L
Sbjct: 207 GIFQFTSTSTGQL 219
>AY513609-1|AAR90940.1| 494|Homo sapiens cytochrome P450 2A13
variant 6 protein.
Length = 494
Score = 84.6 bits (200), Expect = 4e-16
Identities = 69/228 (30%), Positives = 102/228 (44%), Gaps = 5/228 (2%)
Frame = +1
Query: 94 RRHRGLCYPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 273
R+ RG PPGPTPLP +GN + + E + S++YG + + LG VVV
Sbjct: 27 RKSRGKL-PPGPTPLPFIGNYLQLNTEQMYNSLMKI-----SERYGPVFTIHLGPRRVVV 80
Query: 274 VTGIELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNF 447
+ G + +KE V E F GR G T K G+ FS+G + RRF + L+ F
Sbjct: 81 LCGHDAVKEALVDQAEEFSGR--GEQATFDWLFKGYGVAFSNGERAKQLRRFSIATLRGF 138
Query: 448 GYNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRL 627
G R + I EE L+ G I T+ N++ +V G R+D D+
Sbjct: 139 GVGKRGIEERIQEEAGFLIDALRGTHGANIDPTFFLSRTVSNVISSIVFGDRFDYEDKEF 198
Query: 628 KKLCNLVMRLFKLXDMSGGIL--NFLPFLXHFI-PRLIGFTELQXIHN 762
L +++ F+ S G L F + H P+ F ELQ + +
Sbjct: 199 LSLLRMMLGSFQFTATSTGQLYEMFSSVMKHLPGPQQQAFKELQGLED 246
>AY513606-1|AAR90937.1| 494|Homo sapiens cytochrome P450 2A13
variant 3 protein.
Length = 494
Score = 84.6 bits (200), Expect = 4e-16
Identities = 69/228 (30%), Positives = 102/228 (44%), Gaps = 5/228 (2%)
Frame = +1
Query: 94 RRHRGLCYPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 273
R+ RG PPGPTPLP +GN + + E + S++YG + + LG VVV
Sbjct: 27 RKSRGKL-PPGPTPLPFIGNYLQLNTEQMYNSLMKI-----SERYGPVFTIHLGPRRVVV 80
Query: 274 VTGIELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNF 447
+ G + +KE V E F GR G T K G+ FS+G + RRF + L+ F
Sbjct: 81 LCGHDAVKEALVDQAEEFSGR--GEQATFDWLFKGYGVAFSNGERAKQLRRFSIATLRGF 138
Query: 448 GYNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRL 627
G R + I EE L+ G I T+ N++ +V G R+D D+
Sbjct: 139 GVGKRGIEERIQEEAGFLIDALRGTHGANIDPTFFLSRTVSNVISSIVFGDRFDYEDKEF 198
Query: 628 KKLCNLVMRLFKLXDMSGGIL--NFLPFLXHFI-PRLIGFTELQXIHN 762
L +++ F+ S G L F + H P+ F ELQ + +
Sbjct: 199 LSLLRMMLGSFQFTATSTGQLYEMFSSVMKHLPGPQQQAFKELQGLED 246
>AY513605-1|AAR90936.1| 494|Homo sapiens cytochrome P450 2A13
variant 2 protein.
Length = 494
Score = 84.6 bits (200), Expect = 4e-16
Identities = 69/228 (30%), Positives = 102/228 (44%), Gaps = 5/228 (2%)
Frame = +1
Query: 94 RRHRGLCYPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 273
R+ RG PPGPTPLP +GN + + E + S++YG + + LG VVV
Sbjct: 27 RKSRGKL-PPGPTPLPFIGNYLQLNTEQMYNSLMKI-----SERYGPVFTIHLGPRRVVV 80
Query: 274 VTGIELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNF 447
+ G + +KE V E F GR G T K G+ FS+G + RRF + L+ F
Sbjct: 81 LCGHDAVKEALVDQAEEFSGR--GEQATFDWLFKGYGVAFSNGERAKQLRRFSIATLRGF 138
Query: 448 GYNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRL 627
G R + I EE L+ G I T+ N++ +V G R+D D+
Sbjct: 139 GVGKRGIEERIQEEAGFLIDALRGTHGANIDPTFFLSRTVSNVISSIVFGDRFDYEDKEF 198
Query: 628 KKLCNLVMRLFKLXDMSGGIL--NFLPFLXHFI-PRLIGFTELQXIHN 762
L +++ F+ S G L F + H P+ F ELQ + +
Sbjct: 199 LSLLRMMLGSFQFTATSTGQLYEMFSSVMKHLPGPQQQAFKELQGLED 246
>AY513604-1|AAR90935.1| 494|Homo sapiens cytochrome P450 2A13
variant 1 protein.
Length = 494
Score = 84.6 bits (200), Expect = 4e-16
Identities = 69/228 (30%), Positives = 102/228 (44%), Gaps = 5/228 (2%)
Frame = +1
Query: 94 RRHRGLCYPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 273
R+ RG PPGPTPLP +GN + + E + S++YG + + LG VVV
Sbjct: 27 RKSRGKL-PPGPTPLPFIGNYLQLNTEQMYNSLMKI-----SERYGPVFTIHLGPRRVVV 80
Query: 274 VTGIELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNF 447
+ G + +KE V E F GR G T K G+ FS+G + RRF + L+ F
Sbjct: 81 LCGHDAVKEALVDQAEEFSGR--GEQATFDWLFKGYGVAFSNGERAKQLRRFSIATLRGF 138
Query: 448 GYNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRL 627
G R + I EE L+ G I T+ N++ +V G R+D D+
Sbjct: 139 GVGKRGIEERIQEEAGFLIDALRGTHGANIDPTFFLSRTVSNVISSIVFGDRFDYEDKEF 198
Query: 628 KKLCNLVMRLFKLXDMSGGIL--NFLPFLXHFI-PRLIGFTELQXIHN 762
L +++ F+ S G L F + H P+ F ELQ + +
Sbjct: 199 LSLLRMMLGSFQFTATSTGQLYEMFSSVMKHLPGPQQQAFKELQGLED 246
>AF209774-1|AAG35775.1| 494|Homo sapiens cytochrome P450 2A13
protein.
Length = 494
Score = 84.6 bits (200), Expect = 4e-16
Identities = 69/228 (30%), Positives = 102/228 (44%), Gaps = 5/228 (2%)
Frame = +1
Query: 94 RRHRGLCYPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 273
R+ RG PPGPTPLP +GN + + E + S++YG + + LG VVV
Sbjct: 27 RKSRGKL-PPGPTPLPFIGNYLQLNTEQMYNSLMKI-----SERYGPVFTIHLGPRRVVV 80
Query: 274 VTGIELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNF 447
+ G + +KE V E F GR G T K G+ FS+G + RRF + L+ F
Sbjct: 81 LCGHDAVKEALVDQAEEFSGR--GEQATFDWLFKGYGVAFSNGERAKQLRRFSIATLRGF 138
Query: 448 GYNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRL 627
G R + I EE L+ G I T+ N++ +V G R+D D+
Sbjct: 139 GVGKRGIEERIQEEAGFLIDALRGTHGANIDPTFFLSRTVSNVISSIVFGDRFDYEDKEF 198
Query: 628 KKLCNLVMRLFKLXDMSGGIL--NFLPFLXHFI-PRLIGFTELQXIHN 762
L +++ F+ S G L F + H P+ F ELQ + +
Sbjct: 199 LSLLRMMLGSFQFTATSTGQLYEMFSSVMKHLPGPQQQAFKELQGLED 246
>AF182275-1|AAF13600.1| 494|Homo sapiens cytochrome P450-2A6
protein.
Length = 494
Score = 84.6 bits (200), Expect = 4e-16
Identities = 59/193 (30%), Positives = 90/193 (46%), Gaps = 2/193 (1%)
Frame = +1
Query: 118 PPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIK 297
PPGPTPLP +GN + + E + S++YG + + LG VVV+ G + ++
Sbjct: 34 PPGPTPLPFIGNYLQLNTEQMYNSLMKI-----SERYGPVFTIHLGPRRVVVLCGHDAVR 88
Query: 298 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 471
E V E F GR G T K G+VFS+G + RRF + L++FG R +
Sbjct: 89 EALVDQAEEFSGR--GEQATFDWVFKGYGVVFSNGERAKQLRRFSIATLRDFGVGKRGIE 146
Query: 472 VYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCNLVM 651
I EE L+ G I T+ N++ +V G R+D D+ L +++
Sbjct: 147 ERIQEEAGFLIDALRGTGGANIDPTFFLSRTVSNVISSIVFGDRFDYKDKEFLSLLRMML 206
Query: 652 RLFKLXDMSGGIL 690
+F+ S G L
Sbjct: 207 GIFQFTSTSTGQL 219
>M61856-1|AAB59356.1| 490|Homo sapiens cytochrome protein.
Length = 490
Score = 84.2 bits (199), Expect = 5e-16
Identities = 61/206 (29%), Positives = 95/206 (46%), Gaps = 4/206 (1%)
Frame = +1
Query: 118 PPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIK 297
P GPTPLP++GN++ + K ++S+ YG + + G +VV+ G E +K
Sbjct: 30 PSGPTPLPIIGNILQL-----DVKDMSKSLTNFSKVYGPVFTVYFGLKPIVVLHGYEAVK 84
Query: 298 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 471
E + + E F GR G F K LG++FS+G W RRF L L+NFG R +
Sbjct: 85 EALIDHGEEFSGR--GSFPVAEKVNKGLGILFSNGKRWKEIRRFCLMTLRNFGMGKRSIE 142
Query: 472 VYIGEECEALV-QLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCNLV 648
+ EE LV +LR +A P + N++ ++ R+D DQR L
Sbjct: 143 DRVQEEARCLVEELRKTNA-SPCDPTFILGCAPCNVICSVIFHDRFDYKDQRFLNLMEKF 201
Query: 649 MRLFKLXDMSG-GILNFLPFLXHFIP 723
++ + N P L ++P
Sbjct: 202 NENLRILSSPWIQVCNNFPALIDYLP 227
>L16876-1|AAA02630.1| 490|Homo sapiens cytochrome P-4502C18
protein.
Length = 490
Score = 84.2 bits (199), Expect = 5e-16
Identities = 61/206 (29%), Positives = 95/206 (46%), Gaps = 4/206 (1%)
Frame = +1
Query: 118 PPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIK 297
P GPTPLP++GN++ + K ++S+ YG + + G +VV+ G E +K
Sbjct: 30 PSGPTPLPIIGNILQL-----DVKDMSKSLTNFSKVYGPVFTVYFGLKPIVVLHGYEAVK 84
Query: 298 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 471
E + + E F GR G F K LG++FS+G W RRF L L+NFG R +
Sbjct: 85 EALIDHGEEFSGR--GSFPVAEKVNKGLGILFSNGKRWKEIRRFCLMTLRNFGMGKRSIE 142
Query: 472 VYIGEECEALV-QLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCNLV 648
+ EE LV +LR +A P + N++ ++ R+D DQR L
Sbjct: 143 DRVQEEARCLVEELRKTNA-SPCDPTFILGCAPCNVICSVIFHDRFDYKDQRFLNLMEKF 201
Query: 649 MRLFKLXDMSG-GILNFLPFLXHFIP 723
++ + N P L ++P
Sbjct: 202 NENLRILSSPWIQVCNNFPALIDYLP 227
>BC096259-1|AAH96259.1| 443|Homo sapiens CYP2C18 protein protein.
Length = 443
Score = 84.2 bits (199), Expect = 5e-16
Identities = 61/206 (29%), Positives = 95/206 (46%), Gaps = 4/206 (1%)
Frame = +1
Query: 118 PPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIK 297
P GPTPLP++GN++ + K ++S+ YG + + G +VV+ G E +K
Sbjct: 30 PSGPTPLPIIGNILQL-----DVKDMSKSLTNFSKVYGPVFTVYFGLKPIVVLHGYEAVK 84
Query: 298 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 471
E + + E F GR G F K LG++FS+G W RRF L L+NFG R +
Sbjct: 85 EALIDHGEEFSGR--GSFPVAEKVNKGLGILFSNGKRWKEIRRFCLMTLRNFGMGKRSIE 142
Query: 472 VYIGEECEALV-QLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCNLV 648
+ EE LV +LR +A P + N++ ++ R+D DQR L
Sbjct: 143 DRVQEEARCLVEELRKTNA-SPCDPTFILGCAPCNVICSVIFHDRFDYKDQRFLNLMEKF 201
Query: 649 MRLFKLXDMSG-GILNFLPFLXHFIP 723
++ + N P L ++P
Sbjct: 202 NENLRILSSPWIQVCNNFPALIDYLP 227
>BC096258-1|AAH96258.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 protein.
Length = 490
Score = 84.2 bits (199), Expect = 5e-16
Identities = 61/206 (29%), Positives = 95/206 (46%), Gaps = 4/206 (1%)
Frame = +1
Query: 118 PPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIK 297
P GPTPLP++GN++ + K ++S+ YG + + G +VV+ G E +K
Sbjct: 30 PSGPTPLPIIGNILQL-----DVKDMSKSLTNFSKVYGPVFTVYFGLKPIVVLHGYEAVK 84
Query: 298 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 471
E + + E F GR G F K LG++FS+G W RRF L L+NFG R +
Sbjct: 85 EALIDHGEEFSGR--GSFPVAEKVNKGLGILFSNGKRWKEIRRFCLMTLRNFGMGKRSIE 142
Query: 472 VYIGEECEALV-QLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCNLV 648
+ EE LV +LR +A P + N++ ++ R+D DQR L
Sbjct: 143 DRVQEEARCLVEELRKTNA-SPCDPTFILGCAPCNVICSVIFHDRFDYKDQRFLNLMEKF 201
Query: 649 MRLFKLXDMSG-GILNFLPFLXHFIP 723
++ + N P L ++P
Sbjct: 202 NENLRILSSPWIQVCNNFPALIDYLP 227
>BC096257-1|AAH96257.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 protein.
Length = 490
Score = 84.2 bits (199), Expect = 5e-16
Identities = 61/206 (29%), Positives = 95/206 (46%), Gaps = 4/206 (1%)
Frame = +1
Query: 118 PPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIK 297
P GPTPLP++GN++ + K ++S+ YG + + G +VV+ G E +K
Sbjct: 30 PSGPTPLPIIGNILQL-----DVKDMSKSLTNFSKVYGPVFTVYFGLKPIVVLHGYEAVK 84
Query: 298 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 471
E + + E F GR G F K LG++FS+G W RRF L L+NFG R +
Sbjct: 85 EALIDHGEEFSGR--GSFPVAEKVNKGLGILFSNGKRWKEIRRFCLMTLRNFGMGKRSIE 142
Query: 472 VYIGEECEALV-QLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCNLV 648
+ EE LV +LR +A P + N++ ++ R+D DQR L
Sbjct: 143 DRVQEEARCLVEELRKTNA-SPCDPTFILGCAPCNVICSVIFHDRFDYKDQRFLNLMEKF 201
Query: 649 MRLFKLXDMSG-GILNFLPFLXHFIP 723
++ + N P L ++P
Sbjct: 202 NENLRILSSPWIQVCNNFPALIDYLP 227
>BC069666-1|AAH69666.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 protein.
Length = 490
Score = 84.2 bits (199), Expect = 5e-16
Identities = 61/206 (29%), Positives = 95/206 (46%), Gaps = 4/206 (1%)
Frame = +1
Query: 118 PPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIK 297
P GPTPLP++GN++ + K ++S+ YG + + G +VV+ G E +K
Sbjct: 30 PSGPTPLPIIGNILQL-----DVKDMSKSLTNFSKVYGPVFTVYFGLKPIVVLHGYEAVK 84
Query: 298 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 471
E + + E F GR G F K LG++FS+G W RRF L L+NFG R +
Sbjct: 85 EALIDHGEEFSGR--GSFPVAEKVNKGLGILFSNGKRWKEIRRFCLMTLRNFGMGKRSIE 142
Query: 472 VYIGEECEALV-QLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCNLV 648
+ EE LV +LR +A P + N++ ++ R+D DQR L
Sbjct: 143 DRVQEEARCLVEELRKTNA-SPCDPTFILGCAPCNVICSVIFHDRFDYKDQRFLNLMEKF 201
Query: 649 MRLFKLXDMSG-GILNFLPFLXHFIP 723
++ + N P L ++P
Sbjct: 202 NENLRILSSPWIQVCNNFPALIDYLP 227
>AL583836-1|CAH74067.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 protein.
Length = 490
Score = 84.2 bits (199), Expect = 5e-16
Identities = 61/206 (29%), Positives = 95/206 (46%), Gaps = 4/206 (1%)
Frame = +1
Query: 118 PPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIK 297
P GPTPLP++GN++ + K ++S+ YG + + G +VV+ G E +K
Sbjct: 30 PSGPTPLPIIGNILQL-----DVKDMSKSLTNFSKVYGPVFTVYFGLKPIVVLHGYEAVK 84
Query: 298 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 471
E + + E F GR G F K LG++FS+G W RRF L L+NFG R +
Sbjct: 85 EALIDHGEEFSGR--GSFPVAEKVNKGLGILFSNGKRWKEIRRFCLMTLRNFGMGKRSIE 142
Query: 472 VYIGEECEALV-QLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCNLV 648
+ EE LV +LR +A P + N++ ++ R+D DQR L
Sbjct: 143 DRVQEEARCLVEELRKTNA-SPCDPTFILGCAPCNVICSVIFHDRFDYKDQRFLNLMEKF 201
Query: 649 MRLFKLXDMSG-GILNFLPFLXHFIP 723
++ + N P L ++P
Sbjct: 202 NENLRILSSPWIQVCNNFPALIDYLP 227
>U22029-1|AAB40520.1| 494|Homo sapiens cytochrome P450 protein.
Length = 494
Score = 83.8 bits (198), Expect = 6e-16
Identities = 60/201 (29%), Positives = 98/201 (48%), Gaps = 2/201 (0%)
Frame = +1
Query: 94 RRHRGLCYPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 273
R+ RG PPGPTPLP +GN + + + + C ++ +S+ YG + + LG VVV
Sbjct: 27 RKSRGKL-PPGPTPLPFIGNYLQL---NTEHICDSIM--KFSECYGPVFTIHLGPRRVVV 80
Query: 274 VTGIELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNF 447
+ G + ++E V E F GR G T K G+ FS+G + RF + L++F
Sbjct: 81 LCGHDAVREALVDQAEEFSGR--GEQATFEWVFKGYGVAFSNGERAKQLLRFAIATLRDF 138
Query: 448 GYNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRL 627
G R + I EE L++ + G I T+ N++ +V G R+D D+
Sbjct: 139 GVGKRGIEERIQEESGFLIEAIRSTHGANIDPTFFLSRTVSNVISSIVFGDRFDYEDKEF 198
Query: 628 KKLCNLVMRLFKLXDMSGGIL 690
L ++++ +F+ S G L
Sbjct: 199 LSLLSMMLGIFQFTSTSTGQL 219
>BC096260-1|AAH96260.1| 431|Homo sapiens CYP2C18 protein protein.
Length = 431
Score = 83.8 bits (198), Expect = 6e-16
Identities = 57/176 (32%), Positives = 86/176 (48%), Gaps = 3/176 (1%)
Frame = +1
Query: 118 PPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIK 297
P GPTPLP++GN++ + K ++S+ YG + + G +VV+ G E +K
Sbjct: 30 PSGPTPLPIIGNILQL-----DVKDMSKSLTNFSKVYGPVFTVYFGLKPIVVLHGYEAVK 84
Query: 298 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 471
E + + E F GR G F K LG++FS+G W RRF L L+NFG R +
Sbjct: 85 EALIDHGEEFSGR--GSFPVAEKVNKGLGILFSNGKRWKEIRRFCLMTLRNFGMGKRSIE 142
Query: 472 VYIGEECEALV-QLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKL 636
+ EE LV +LR +A P + N++ ++ R+D DQR L
Sbjct: 143 DRVQEEARCLVEELRKTNA-SPCDPTFILGCAPCNVICSVIFHDRFDYKDQRFLNL 197
>M33317-1|AAA52138.1| 494|Homo sapiens CYP2A protein.
Length = 494
Score = 83.4 bits (197), Expect = 8e-16
Identities = 60/201 (29%), Positives = 98/201 (48%), Gaps = 2/201 (0%)
Frame = +1
Query: 94 RRHRGLCYPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 273
R+ RG PPGPTPLP +GN + + + + C ++ +S+ YG + + LG VVV
Sbjct: 27 RKSRGKL-PPGPTPLPFIGNYLQL---NTEHICDSIM--KFSECYGPVFTIHLGPRRVVV 80
Query: 274 VTGIELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNF 447
+ G + ++E V E F GR G T K G+ FS+G + RF + L++F
Sbjct: 81 LCGHDAVREALVDQAEEFSGR--GEQATFDWVFKGYGVAFSNGERAKQLLRFAIATLRDF 138
Query: 448 GYNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRL 627
G R + I EE L++ + G I T+ N++ +V G R+D D+
Sbjct: 139 GVGKRGIEERIQEESGFLIEAIRSSHGANIDPTFFLSRTVSNVISSIVFGDRFDYEDKEF 198
Query: 628 KKLCNLVMRLFKLXDMSGGIL 690
L ++++ +F+ S G L
Sbjct: 199 LSLLSMMLGIFQFTSTSTGQL 219
>AK223510-1|BAD97230.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 variant protein.
Length = 490
Score = 83.0 bits (196), Expect = 1e-15
Identities = 61/206 (29%), Positives = 95/206 (46%), Gaps = 4/206 (1%)
Frame = +1
Query: 118 PPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIK 297
P GPTPLP++GN++ + K ++S+ YG + + G +VV+ G E +K
Sbjct: 30 PSGPTPLPIIGNILQL-----DVKDMSKSLTNFSKVYGPVFTVYFGLKPIVVLHGYEAVK 84
Query: 298 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 471
E + + E F GR G F K LG++FS+G W RRF L L+NFG R +
Sbjct: 85 EALIDHGEEFFGR--GSFPVAEKVNKGLGILFSNGKRWKEIRRFCLMTLRNFGMGKRSIE 142
Query: 472 VYIGEECEALV-QLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCNLV 648
+ EE LV +LR +A P + N++ ++ R+D DQR L
Sbjct: 143 DRVQEEARCLVEELRKTNA-SPCDPTFILGCAPCNVICSVIFHDRFDYKDQRFLNLMEKF 201
Query: 649 MRLFKLXDMSG-GILNFLPFLXHFIP 723
++ + N P L ++P
Sbjct: 202 NENLRILSSPWIQVCNNFPALIDYLP 227
>J02843-1|AAA52155.1| 493|Homo sapiens protein ( Human cytochrome
P450IIE1 (ethanol-inducible) gene, complete cds. ).
Length = 493
Score = 82.6 bits (195), Expect = 1e-15
Identities = 58/212 (27%), Positives = 98/212 (46%), Gaps = 4/212 (1%)
Frame = +1
Query: 100 HRGLCYPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVT 279
H PPGP PLP++GNL + + K + +Q++G + L +GS +VV+
Sbjct: 27 HSSWNLPPGPFPLPIIGNLFQL-----ELKNIPKSFTRLAQRFGPVFTLYVGSQRMVVMH 81
Query: 280 GIELIKE--VSNREVFEGRPD-GFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFG 450
G + +KE + ++ F GR D F+ R G++F++GPTW RRF L L+N+G
Sbjct: 82 GYKAVKEALLDYKDEFSGRGDLPAFHAHRD----RGIIFNNGPTWKDIRRFSLTTLRNYG 137
Query: 451 YNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLK 630
+ I E L++ G+P + N++ ++ K +D D++
Sbjct: 138 MGKQGNESRIQREAHFLLEALRKTQGQPFDPTFLIGCAPCNVIADILFRKHFDYNDEKFL 197
Query: 631 KLCNLVMRLFKLXDMSG-GILNFLPFLXHFIP 723
+L L F L + N P H++P
Sbjct: 198 RLMYLFNENFHLLSTPWLQLYNNFPSFLHYLP 229
>J02625-1|AAA35743.1| 493|Homo sapiens protein ( Human cytochrome
P-450j mRNA, complete cds. ).
Length = 493
Score = 82.6 bits (195), Expect = 1e-15
Identities = 58/212 (27%), Positives = 98/212 (46%), Gaps = 4/212 (1%)
Frame = +1
Query: 100 HRGLCYPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVT 279
H PPGP PLP++GNL + + K + +Q++G + L +GS +VV+
Sbjct: 27 HSSWNLPPGPFPLPIIGNLFQL-----ELKNIPKSFTRLAQRFGPVFTLYVGSQRMVVMH 81
Query: 280 GIELIKE--VSNREVFEGRPD-GFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFG 450
G + +KE + ++ F GR D F+ R G++F++GPTW RRF L L+N+G
Sbjct: 82 GYKAVKEALLDYKDEFSGRGDLPAFHAHRD----RGIIFNNGPTWKDIRRFSLTTLRNYG 137
Query: 451 YNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLK 630
+ I E L++ G+P + N++ ++ K +D D++
Sbjct: 138 MGKQGNESRIQREAHFLLEALRKTQGQPFDPTFLIGCAPCNVIADILFRKHFDYNDEKFL 197
Query: 631 KLCNLVMRLFKLXDMSG-GILNFLPFLXHFIP 723
+L L F L + N P H++P
Sbjct: 198 RLMYLFNENFHLLSTPWLQLYNNFPSFLHYLP 229
>DQ515958-1|ABF47105.1| 493|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 1 protein.
Length = 493
Score = 82.6 bits (195), Expect = 1e-15
Identities = 58/212 (27%), Positives = 98/212 (46%), Gaps = 4/212 (1%)
Frame = +1
Query: 100 HRGLCYPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVT 279
H PPGP PLP++GNL + + K + +Q++G + L +GS +VV+
Sbjct: 27 HSSWNLPPGPFPLPIIGNLFQL-----ELKNIPKSFTRLAQRFGPVFTLYVGSQRMVVMH 81
Query: 280 GIELIKE--VSNREVFEGRPD-GFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFG 450
G + +KE + ++ F GR D F+ R G++F++GPTW RRF L L+N+G
Sbjct: 82 GYKAVKEALLDYKDEFSGRGDLPAFHAHRD----RGIIFNNGPTWKDIRRFSLTTLRNYG 137
Query: 451 YNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLK 630
+ I E L++ G+P + N++ ++ K +D D++
Sbjct: 138 MGKQGNESRIQREAHFLLEALRKTQGQPFDPTFLIGCAPCNVIADILFRKHFDYNDEKFL 197
Query: 631 KLCNLVMRLFKLXDMSG-GILNFLPFLXHFIP 723
+L L F L + N P H++P
Sbjct: 198 RLMYLFNENFHLLSTPWLQLYNNFPSFLHYLP 229
>DQ149222-1|AAZ77710.1| 493|Homo sapiens cytochrome P450 2E1
protein.
Length = 493
Score = 82.6 bits (195), Expect = 1e-15
Identities = 58/212 (27%), Positives = 98/212 (46%), Gaps = 4/212 (1%)
Frame = +1
Query: 100 HRGLCYPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVT 279
H PPGP PLP++GNL + + K + +Q++G + L +GS +VV+
Sbjct: 27 HSSWNLPPGPFPLPIIGNLFQL-----ELKNIPKSFTRLAQRFGPVFTLYVGSQRMVVMH 81
Query: 280 GIELIKE--VSNREVFEGRPD-GFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFG 450
G + +KE + ++ F GR D F+ R G++F++GPTW RRF L L+N+G
Sbjct: 82 GYKAVKEALLDYKDEFSGRGDLPAFHAHRD----RGIIFNNGPTWKDIRRFSLTTLRNYG 137
Query: 451 YNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLK 630
+ I E L++ G+P + N++ ++ K +D D++
Sbjct: 138 MGKQGNESRIQREAHFLLEALRKTQGQPFDPTFLIGCAPCNVIADILFRKHFDYNDEKFL 197
Query: 631 KLCNLVMRLFKLXDMSG-GILNFLPFLXHFIP 723
+L L F L + N P H++P
Sbjct: 198 RLMYLFNENFHLLSTPWLQLYNNFPSFLHYLP 229
>AL161645-2|CAH70047.1| 493|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 1 protein.
Length = 493
Score = 82.6 bits (195), Expect = 1e-15
Identities = 58/212 (27%), Positives = 98/212 (46%), Gaps = 4/212 (1%)
Frame = +1
Query: 100 HRGLCYPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVT 279
H PPGP PLP++GNL + + K + +Q++G + L +GS +VV+
Sbjct: 27 HSSWNLPPGPFPLPIIGNLFQL-----ELKNIPKSFTRLAQRFGPVFTLYVGSQRMVVMH 81
Query: 280 GIELIKE--VSNREVFEGRPD-GFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFG 450
G + +KE + ++ F GR D F+ R G++F++GPTW RRF L L+N+G
Sbjct: 82 GYKAVKEALLDYKDEFSGRGDLPAFHAHRD----RGIIFNNGPTWKDIRRFSLTTLRNYG 137
Query: 451 YNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLK 630
+ I E L++ G+P + N++ ++ K +D D++
Sbjct: 138 MGKQGNESRIQREAHFLLEALRKTQGQPFDPTFLIGCAPCNVIADILFRKHFDYNDEKFL 197
Query: 631 KLCNLVMRLFKLXDMSG-GILNFLPFLXHFIP 723
+L L F L + N P H++P
Sbjct: 198 RLMYLFNENFHLLSTPWLQLYNNFPSFLHYLP 229
>AF182276-1|AAF13601.1| 493|Homo sapiens cytochrome P450-2E1
protein.
Length = 493
Score = 82.6 bits (195), Expect = 1e-15
Identities = 58/212 (27%), Positives = 98/212 (46%), Gaps = 4/212 (1%)
Frame = +1
Query: 100 HRGLCYPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVT 279
H PPGP PLP++GNL + + K + +Q++G + L +GS +VV+
Sbjct: 27 HSSWNLPPGPFPLPIIGNLFQL-----ELKNIPKSFTRLAQRFGPVFTLYVGSQRMVVMH 81
Query: 280 GIELIKE--VSNREVFEGRPD-GFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFG 450
G + +KE + ++ F GR D F+ R G++F++GPTW RRF L L+N+G
Sbjct: 82 GYKAVKEALLDYKDEFSGRGDLPAFHAHRD----RGIIFNNGPTWKDIRRFSLTTLRNYG 137
Query: 451 YNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLK 630
+ I E L++ G+P + N++ ++ K +D D++
Sbjct: 138 MGKQGNESRIQREAHFLLEALRKTQGQPFDPTFLIGCAPCNVIADILFRKHFDYNDEKFL 197
Query: 631 KLCNLVMRLFKLXDMSG-GILNFLPFLXHFIP 723
+L L F L + N P H++P
Sbjct: 198 RLMYLFNENFHLLSTPWLQLYNNFPSFLHYLP 229
>U22027-1|AAB40518.1| 494|Homo sapiens cytochrome P450 protein.
Length = 494
Score = 82.2 bits (194), Expect = 2e-15
Identities = 58/193 (30%), Positives = 91/193 (47%), Gaps = 2/193 (1%)
Frame = +1
Query: 118 PPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIK 297
PPGPTPLP +GN + + E + S++YG + + LG VVV+ G + ++
Sbjct: 34 PPGPTPLPFIGNYLQLNTEQMYNSLMKI-----SERYGPVFTIHLGPRRVVVLCGHDAVR 88
Query: 298 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 471
E V E F GR G T K G+VFS+G + RF + L++FG R +
Sbjct: 89 EALVDQAEEFSGR--GEQATFDWVFKGYGVVFSNGERAKQLLRFAIATLRDFGVGKRGIE 146
Query: 472 VYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCNLVM 651
I EE L++ + G I T+ N++ +V G R+D D+ L +++
Sbjct: 147 ERIQEESGFLIEAIRSTHGANIDPTFFLSRTVSNVISSIVFGDRFDYKDKEFLSLLRMML 206
Query: 652 RLFKLXDMSGGIL 690
+F+ S G L
Sbjct: 207 GIFQFTSTSTGQL 219
>BC067433-1|AAH67433.1| 493|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 1 protein.
Length = 493
Score = 82.2 bits (194), Expect = 2e-15
Identities = 58/212 (27%), Positives = 98/212 (46%), Gaps = 4/212 (1%)
Frame = +1
Query: 100 HRGLCYPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVT 279
H PPGP PLP++GNL + + K + +Q++G + L +GS +VV+
Sbjct: 27 HSSWNLPPGPFPLPIIGNLFQL-----ELKNIPKSFTRLAQRFGPVFTLCVGSQRMVVMH 81
Query: 280 GIELIKE--VSNREVFEGRPD-GFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFG 450
G + +KE + ++ F GR D F+ R G++F++GPTW RRF L L+N+G
Sbjct: 82 GYKAVKEALLDYKDEFSGRGDLPAFHAHRD----RGIIFNNGPTWKDIRRFSLTTLRNYG 137
Query: 451 YNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLK 630
+ I E L++ G+P + N++ ++ K +D D++
Sbjct: 138 MGKQGNESRIQREAHFLLEALRKTQGQPFDPTFLIGCAPCNVIADILFRKHFDYNDEKFL 197
Query: 631 KLCNLVMRLFKLXDMSG-GILNFLPFLXHFIP 723
+L L F L + N P H++P
Sbjct: 198 RLMYLFNENFHLLSTPWLQLYNNFPSFLHYLP 229
>AF084225-1|AAD13753.1| 462|Homo sapiens cytochrome P450 2E1
protein.
Length = 462
Score = 82.2 bits (194), Expect = 2e-15
Identities = 57/206 (27%), Positives = 97/206 (47%), Gaps = 4/206 (1%)
Frame = +1
Query: 118 PPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIK 297
PPGP PLP++GNL + + K + +Q++G + L +GS +VV+ G + +K
Sbjct: 2 PPGPFPLPIIGNLFQL-----ELKNIPKSFTRLAQRFGPVFTLYVGSQRMVVMHGYKAVK 56
Query: 298 E--VSNREVFEGRPD-GFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFM 468
E + ++ F GR D F+ R G++F++GPTW RRF L L+N+G +
Sbjct: 57 EALLDYKDEFSGRGDLPAFHAHRD----RGIIFNNGPTWKDIRRFSLTTLRNYGMGKQGN 112
Query: 469 NVYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCNLV 648
I E L++ G+P + N++ ++ K +D D++ +L L
Sbjct: 113 ESRIQREAHFLLEALRKTQGQPFDPTFLIGCAPCNVIADILFRKHFDYNDEKFLRLMYLF 172
Query: 649 MRLFKLXDMSG-GILNFLPFLXHFIP 723
F L + N P H++P
Sbjct: 173 NENFHLLSTPWLQLYNNFPSFLHYLP 198
>BC117165-1|AAI17166.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 7 protein.
Length = 494
Score = 81.0 bits (191), Expect = 5e-15
Identities = 59/201 (29%), Positives = 97/201 (48%), Gaps = 2/201 (0%)
Frame = +1
Query: 94 RRHRGLCYPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 273
R+ RG PPGPTPLP +GN + + + + C ++ +S+ YG + + LG VV
Sbjct: 27 RKSRGKL-PPGPTPLPFIGNYLQL---NTEHICDSIM--KFSECYGPVFTIHLGPRRAVV 80
Query: 274 VTGIELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNF 447
+ G + ++E V E F GR G T K G+ FS+G + RF + L++F
Sbjct: 81 LCGHDAVREALVDQAEEFSGR--GEQATFDWVFKGYGVAFSNGERAKQLLRFAIATLRDF 138
Query: 448 GYNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRL 627
G R + I EE L++ + G I T+ N++ +V G R+D D+
Sbjct: 139 GVGKRGIEERIQEESGFLIEAIRSTHGANIDPTFFLSRTVSNVISSIVFGDRFDYEDKEF 198
Query: 628 KKLCNLVMRLFKLXDMSGGIL 690
L ++++ +F+ S G L
Sbjct: 199 LSLLSVMLGIFQFTSTSTGQL 219
>BC067435-1|AAH67435.1| 493|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 1 protein.
Length = 493
Score = 80.6 bits (190), Expect = 6e-15
Identities = 57/212 (26%), Positives = 97/212 (45%), Gaps = 4/212 (1%)
Frame = +1
Query: 100 HRGLCYPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVT 279
H PPGP PLP++GNL + + K + +Q++G + L +GS +VV+
Sbjct: 27 HSSWNLPPGPFPLPIIGNLFQL-----ELKNIPKSFTRLAQRFGPVFTLYVGSQRMVVMH 81
Query: 280 GIELIKE--VSNREVFEGRPD-GFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFG 450
G + +KE + ++ F GR D F+ R G++F++GP W RRF L L+N+G
Sbjct: 82 GYKAVKEALLDYKDEFSGRGDLPAFHAHRD----RGIIFNNGPAWKDIRRFSLTTLRNYG 137
Query: 451 YNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLK 630
+ I E L++ G+P + N++ ++ K +D D++
Sbjct: 138 MGKQGNESRIQREAHFLLEALRKTQGQPFDPTFLIGCAPCNVIADILFRKHFDYNDEKFL 197
Query: 631 KLCNLVMRLFKLXDMSG-GILNFLPFLXHFIP 723
+L L F L + N P H++P
Sbjct: 198 RLMYLFNENFHLLSTPWLQLYNNFPSFLHYLP 229
>S63426-1|ABB76283.1| 214|Homo sapiens (S)-mephenytoin hydroxylase
associated cytochrome P450 protein.
Length = 214
Score = 78.6 bits (185), Expect = 2e-14
Identities = 55/172 (31%), Positives = 83/172 (48%), Gaps = 3/172 (1%)
Frame = +1
Query: 118 PPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIK 297
P GPTPLP++GN++ + K ++S+ YG + + G +VV+ G E +K
Sbjct: 30 PSGPTPLPIIGNILQL-----DVKDMSKSLTNFSKVYGPVFTVYFGLKPIVVLHGYEAVK 84
Query: 298 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 471
E + + E F GR G F K LG++FS+G W RF L L+NFG R +
Sbjct: 85 EALIDHGEEFSGR--GSFPVAEKVNKGLGILFSNGKRWKEIWRFCLMTLRNFGMGKRSIE 142
Query: 472 VYIGEECEALV-QLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQR 624
+ EE LV +LR +A P + N+ ++ R+D DQR
Sbjct: 143 DRVQEEARCLVEELRKTNA-SPCDPTFILGCAPCNVTCSVIFHDRFDYKDQR 193
>L39098-1|AAL31347.1| 160|Homo sapiens S-mephenytoin 4-hydroxylase
protein.
Length = 160
Score = 77.8 bits (183), Expect = 4e-14
Identities = 48/132 (36%), Positives = 68/132 (51%), Gaps = 2/132 (1%)
Frame = +1
Query: 118 PPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIK 297
PPGPTPLPV+GN++ + + +L S+ YG + L G +VV+ G E++K
Sbjct: 30 PPGPTPLPVIGNILQIDIKDVSKSLTNL-----SKIYGPVFTLYFGLERMVVLHGYEVVK 84
Query: 298 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 471
E + E F GR G F + G+VFS+G W RRF L L+NFG R +
Sbjct: 85 EALIDLGEEFSGR--GHFPLAERANRGFGIVFSNGKRWKEIRRFSLMTLRNFGMGKRSIE 142
Query: 472 VYIGEECEALVQ 507
+ EE LV+
Sbjct: 143 DRVQEEARCLVE 154
>BC070317-1|AAH70317.1| 162|Homo sapiens CYP2C9 protein protein.
Length = 162
Score = 77.8 bits (183), Expect = 4e-14
Identities = 48/132 (36%), Positives = 67/132 (50%), Gaps = 2/132 (1%)
Frame = +1
Query: 118 PPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIK 297
PPGPTPLPV+GN++ + + +L S+ YG + L G +VV+ G E +K
Sbjct: 30 PPGPTPLPVIGNILQIGIKDISKSLTNL-----SKVYGPVFTLYFGLKPIVVLHGYEAVK 84
Query: 298 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 471
E + E F GR G F + G+VFS+G W RRF L L+NFG R +
Sbjct: 85 EALIDLGEEFSGR--GIFPLAERANRGFGIVFSNGKKWKEIRRFSLMTLRNFGMGKRSIE 142
Query: 472 VYIGEECEALVQ 507
+ EE LV+
Sbjct: 143 DCVQEEARCLVE 154
>BC020754-1|AAH20754.1| 162|Homo sapiens CYP2C9 protein protein.
Length = 162
Score = 77.8 bits (183), Expect = 4e-14
Identities = 48/132 (36%), Positives = 67/132 (50%), Gaps = 2/132 (1%)
Frame = +1
Query: 118 PPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIK 297
PPGPTPLPV+GN++ + + +L S+ YG + L G +VV+ G E +K
Sbjct: 30 PPGPTPLPVIGNILQIGIKDISKSLTNL-----SKVYGPVFTLYFGLKPIVVLHGYEAVK 84
Query: 298 E--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMN 471
E + E F GR G F + G+VFS+G W RRF L L+NFG R +
Sbjct: 85 EALIDLGEEFSGR--GIFPLAERANRGFGIVFSNGKKWKEIRRFSLMTLRNFGMGKRSIE 142
Query: 472 VYIGEECEALVQ 507
+ EE LV+
Sbjct: 143 DRVQEEARCLVE 154
>BC104909-1|AAI04910.1| 501|Homo sapiens cytochrome P450, family 2,
subfamily R, polypeptide 1 protein.
Length = 501
Score = 77.0 bits (181), Expect = 7e-14
Identities = 57/209 (27%), Positives = 91/209 (43%), Gaps = 4/209 (1%)
Frame = +1
Query: 94 RRHRGLCYPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 273
++ R + +PPGP LP +GN+ S+ S + H+ + SQ YG + L LG I+ VV
Sbjct: 32 KQRRPMGFPPGPPGLPFIGNIYSLAASS---ELPHVYMRKQSQVYGEIFSLDLGGISTVV 88
Query: 274 VTGIELIKE--VSNREVFEGRPD-GFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKN 444
+ G +++KE V E+F RP F M G L + G W RR + +
Sbjct: 89 LNGYDVVKECLVHQSEIFADRPCLPLFMKMTKMGGLLNSRYGRG--WVDHRRLAVNSFRY 146
Query: 445 FGYNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQR 624
FGY + I EE + G P Q+ + NI ++ G+R+ D
Sbjct: 147 FGYGQKSFESKILEETKFFNDAIETYKGRPFDFKQLITNAVSNITNLIIFGERFTYEDTD 206
Query: 625 LKKLCNLVMRLFKLXDMSGGIL-NFLPFL 708
+ + L +L + L N P++
Sbjct: 207 FQHMIELFSENVELAASASVFLYNAFPWI 235
>BC104907-1|AAI04908.1| 501|Homo sapiens cytochrome P450, family 2,
subfamily R, polypeptide 1 protein.
Length = 501
Score = 77.0 bits (181), Expect = 7e-14
Identities = 57/209 (27%), Positives = 91/209 (43%), Gaps = 4/209 (1%)
Frame = +1
Query: 94 RRHRGLCYPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 273
++ R + +PPGP LP +GN+ S+ S + H+ + SQ YG + L LG I+ VV
Sbjct: 32 KQRRPMGFPPGPPGLPFIGNIYSLAASS---ELPHVYMRKQSQVYGEIFSLDLGGISTVV 88
Query: 274 VTGIELIKE--VSNREVFEGRPD-GFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKN 444
+ G +++KE V E+F RP F M G L + G W RR + +
Sbjct: 89 LNGYDVVKECLVHQSEIFADRPCLPLFMKMTKMGGLLNSRYGRG--WVDHRRLAVNSFRY 146
Query: 445 FGYNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQR 624
FGY + I EE + G P Q+ + NI ++ G+R+ D
Sbjct: 147 FGYGQKSFESKILEETKFFNDAIETYKGRPFDFKQLITNAVSNITNLIIFGERFTYEDTD 206
Query: 625 LKKLCNLVMRLFKLXDMSGGIL-NFLPFL 708
+ + L +L + L N P++
Sbjct: 207 FQHMIELFSENVELAASASVFLYNAFPWI 235
>AY323817-1|AAQ23114.1| 501|Homo sapiens cytochrome P450 2R1
protein.
Length = 501
Score = 77.0 bits (181), Expect = 7e-14
Identities = 57/209 (27%), Positives = 91/209 (43%), Gaps = 4/209 (1%)
Frame = +1
Query: 94 RRHRGLCYPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 273
++ R + +PPGP LP +GN+ S+ S + H+ + SQ YG + L LG I+ VV
Sbjct: 32 KQRRPMGFPPGPPGLPFIGNIYSLAASS---ELPHVYMRKQSQVYGEIFSLDLGGISTVV 88
Query: 274 VTGIELIKE--VSNREVFEGRPD-GFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKN 444
+ G +++KE V E+F RP F M G L + G W RR + +
Sbjct: 89 LNGYDVVKECLVHQSEIFADRPCLPLFMKMTKMGGLLNSRYGRG--WVDHRRLAVNSFRY 146
Query: 445 FGYNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQR 624
FGY + I EE + G P Q+ + NI ++ G+R+ D
Sbjct: 147 FGYGQKSFESKILEETKFFNDAIETYKGRPFDFKQLITNAVSNITNLIIFGERFTYEDTD 206
Query: 625 LKKLCNLVMRLFKLXDMSGGIL-NFLPFL 708
+ + L +L + L N P++
Sbjct: 207 FQHMIELFSENVELAASASVFLYNAFPWI 235
>BC132767-1|AAI32768.1| 544|Homo sapiens cytochrome P450, family 2,
subfamily U, polypeptide 1 protein.
Length = 544
Score = 76.2 bits (179), Expect = 1e-13
Identities = 72/257 (28%), Positives = 119/257 (46%), Gaps = 23/257 (8%)
Frame = +1
Query: 94 RRHRGLCYPPGPTPLPVVGNLISVL---------WESRKFKCH---------HLIWQSWS 219
RR R PPGPTP P+VGN VL W S + + ++ +
Sbjct: 52 RRRRARGIPPGPTPWPLVGNFGHVLLPPFLRRRSWLSSRTRAAGIDPSVIGPQVLLAHLA 111
Query: 220 QKYGNLLGLRLGSINVVVVTGIELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSD 393
+ YG++ +G VVV++ ++E V EVF RP ++ + K+ G+VF+
Sbjct: 112 RVYGSIFSFFIGHYLVVVLSDFHSVREALVQQAEVFSDRPRVPLISIVT--KEKGVVFAH 169
Query: 394 -GPTWHRTRRFVLKYLKNFGYNSRFMNVYIGEECEALVQLRFADAGE-PILVNQMFHITI 567
GP W + R+F L++FG + I EE + V+ GE P + +
Sbjct: 170 YGPVWRQQRKFSHSTLRHFGLGKLSLEPKIIEEFK-YVKAEMQKHGEDPFCPFSIISNAV 228
Query: 568 VNILWRLVAGKRYDLXDQRLKKLCNLVMRLFKLXDMSGGIL-NFLPFLXHFIPRLIGFTE 744
NI+ L G+R+D + KK+ + R ++ S +L N P+L +++P F E
Sbjct: 229 SNIICSLCFGQRFDYTNSEFKKMLGFMSRGLEICLNSQVLLVNICPWL-YYLP-FGPFKE 286
Query: 745 LQXIHNALHQYLREIIK 795
L+ I + +L++IIK
Sbjct: 287 LRQIEKDITSFLKKIIK 303
>AY343323-1|AAQ21380.1| 544|Homo sapiens cytochrome P450 protein.
Length = 544
Score = 76.2 bits (179), Expect = 1e-13
Identities = 72/257 (28%), Positives = 119/257 (46%), Gaps = 23/257 (8%)
Frame = +1
Query: 94 RRHRGLCYPPGPTPLPVVGNLISVL---------WESRKFKCH---------HLIWQSWS 219
RR R PPGPTP P+VGN VL W S + + ++ +
Sbjct: 52 RRRRARGIPPGPTPWPLVGNFGHVLLPPFLRRRSWLSSRTRAAGIDPSVIGPQVLLAHLA 111
Query: 220 QKYGNLLGLRLGSINVVVVTGIELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSD 393
+ YG++ +G VVV++ ++E V EVF RP ++ + K+ G+VF+
Sbjct: 112 RVYGSIFSFFIGHYLVVVLSDFHSVREALVQQAEVFSDRPRVPLISIVT--KEKGVVFAH 169
Query: 394 -GPTWHRTRRFVLKYLKNFGYNSRFMNVYIGEECEALVQLRFADAGE-PILVNQMFHITI 567
GP W + R+F L++FG + I EE + V+ GE P + +
Sbjct: 170 YGPVWRQQRKFSHSTLRHFGLGKLSLEPKIIEEFK-YVKAEMQKHGEDPFCPFSIISNAV 228
Query: 568 VNILWRLVAGKRYDLXDQRLKKLCNLVMRLFKLXDMSGGIL-NFLPFLXHFIPRLIGFTE 744
NI+ L G+R+D + KK+ + R ++ S +L N P+L +++P F E
Sbjct: 229 SNIICSLCFGQRFDYTNSEFKKMLGFMSRGLEICLNSQVLLVNICPWL-YYLP-FGPFKE 286
Query: 745 LQXIHNALHQYLREIIK 795
L+ I + +L++IIK
Sbjct: 287 LRQIEKDITSFLKKIIK 303
>AM233520-1|CAJ80723.1| 189|Homo sapiens cytochrome P450 1A1
protein.
Length = 189
Score = 76.2 bits (179), Expect = 1e-13
Identities = 45/143 (31%), Positives = 78/143 (54%), Gaps = 9/143 (6%)
Frame = +1
Query: 103 RGLCYPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTG 282
+GL PPGP P++G+++++ K HL SQ+YG++L +R+GS VVV++G
Sbjct: 35 KGLKNPPGPWGWPLIGHMLTL------GKNPHLALSRMSQQYGDVLQIRIGSTPVVVLSG 88
Query: 283 IELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGY- 453
++ I++ V + F+GRPD + +T+ S G+ + GP W RR LK+F
Sbjct: 89 LDTIRQALVRQGDDFKGRPDLYTFTLISNGQSMSFSPDSGPVWAARRRLAQNGLKSFSIA 148
Query: 454 ------NSRFMNVYIGEECEALV 504
S ++ ++ +E E L+
Sbjct: 149 SDPASSTSCYLEEHVSKEAEVLI 171
>AM233519-1|CAJ80722.1| 189|Homo sapiens cytochrome P450 1A1
protein.
Length = 189
Score = 76.2 bits (179), Expect = 1e-13
Identities = 45/143 (31%), Positives = 78/143 (54%), Gaps = 9/143 (6%)
Frame = +1
Query: 103 RGLCYPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTG 282
+GL PPGP P++G+++++ K HL SQ+YG++L +R+GS VVV++G
Sbjct: 35 KGLKNPPGPWGWPLIGHMLTL------GKNPHLALSRMSQQYGDVLQIRIGSTPVVVLSG 88
Query: 283 IELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGY- 453
++ I++ V + F+GRPD + +T+ S G+ + GP W RR LK+F
Sbjct: 89 LDTIRQALVRQGDDFKGRPDLYTFTLISNGQSMSFSPDSGPVWAARRRLAQNGLKSFSIA 148
Query: 454 ------NSRFMNVYIGEECEALV 504
S ++ ++ +E E L+
Sbjct: 149 SDPASSTSCYLEEHVSKEAEVLI 171
>AB209492-1|BAD92729.1| 566|Homo sapiens Debrisoquine 4-hydroxylase
mutant allele variant protein.
Length = 566
Score = 62.1 bits (144), Expect(2) = 1e-12
Identities = 48/177 (27%), Positives = 80/177 (45%), Gaps = 5/177 (2%)
Frame = +1
Query: 220 QKYGNLLGLRLGSINVVVVTGIELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSD 393
+++G++ L+L VVV+ G+ ++E V+ E RP + FG + VF
Sbjct: 133 RRFGDVFSLQLAWTPVVVLNGLAAVREAMVTRGEDTADRPPVPITQILGFGPRSQGVFLA 192
Query: 394 --GPTWHRTRRFVLKYLKNFGYNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITI 567
GP W RRF + L+N G + + ++ EE L FA+ + +
Sbjct: 193 RYGPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACLC-AAFANHSDAPFAPTVSWTKP 251
Query: 568 VNILWRLVAGKRYDLXDQRLKKLCNLVMR-LFKLXDMSGGILNFLPFLXHFIPRLIG 735
N++ L G+R++ D R +L +L L + +LN +P L H IP L G
Sbjct: 252 SNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLH-IPALAG 307
Score = 30.7 bits (66), Expect(2) = 1e-12
Identities = 14/35 (40%), Positives = 22/35 (62%), Gaps = 1/35 (2%)
Frame = +1
Query: 85 IISRRHRGLC-YPPGPTPLPVVGNLISVLWESRKF 186
++ RR R Y PGP PLP +GNL+ V +++ +
Sbjct: 59 LMHRRQRWAARYSPGPLPLPGLGNLLHVDFQNTPY 93
>Z00036-1|CAA77335.1| 515|Homo sapiens protein ( Human mRNA for
cytochrome P-3-450. ).
Length = 515
Score = 71.3 bits (167), Expect = 4e-12
Identities = 58/217 (26%), Positives = 106/217 (48%), Gaps = 13/217 (5%)
Frame = +1
Query: 103 RGLCYPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTG 282
+GL PP P P++G+++++ K HL SQ+YG++L +R+GS V+V++
Sbjct: 37 KGLKSPPEPWGWPLLGHVLTL------GKNPHLALSRMSQRYGDVLQIRIGSTPVLVLSR 90
Query: 283 IELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGY- 453
++ I++ V + F+GRPD + T+ + G+ L GP W RR L F
Sbjct: 91 LDTIRQALVRQGDDFKGRPDLYTSTLITDGQSLTFSTDSGPVWAARRRLAQNALNTFSIA 150
Query: 454 ------NSRFMNVYIGEECEALV---QLRFADAGEPILVNQMFHITIVNILWRLVAGKRY 606
+S ++ ++ +E +AL+ Q A G NQ+ +++ N++ + G+ +
Sbjct: 151 SDPASSSSCYLEEHVSKEAKALISRLQELMAGPGHFDPYNQVV-VSVANVIGAMCFGQHF 209
Query: 607 -DLXDQRLKKLCNLVMRLFKLXDMSGGILNFLPFLXH 714
+ D+ L + N F SG L+F P L +
Sbjct: 210 PESSDEMLSLVKN--THEFVETASSGNPLDFFPILRY 244
>M55053-1|AAA52146.1| 515|Homo sapiens cytochrome P3-450 protein.
Length = 515
Score = 71.3 bits (167), Expect = 4e-12
Identities = 58/217 (26%), Positives = 106/217 (48%), Gaps = 13/217 (5%)
Frame = +1
Query: 103 RGLCYPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTG 282
+GL PP P P++G+++++ K HL SQ+YG++L +R+GS V+V++
Sbjct: 37 KGLKSPPEPWGWPLLGHVLTL------GKNPHLALSRMSQRYGDVLQIRIGSTPVLVLSR 90
Query: 283 IELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGY- 453
++ I++ V + F+GRPD + T+ + G+ L GP W RR L F
Sbjct: 91 LDTIRQALVRQGDDFKGRPDLYTSTLITDGQSLTFSTDSGPVWAARRRLAQNALNTFSIA 150
Query: 454 ------NSRFMNVYIGEECEALV---QLRFADAGEPILVNQMFHITIVNILWRLVAGKRY 606
+S ++ ++ +E +AL+ Q A G NQ+ +++ N++ + G+ +
Sbjct: 151 SDPASSSSCYLEEHVSKEAKALISRLQELMAGPGHFDPYNQVV-VSVANVIGAMCFGQHF 209
Query: 607 -DLXDQRLKKLCNLVMRLFKLXDMSGGILNFLPFLXH 714
+ D+ L + N F SG L+F P L +
Sbjct: 210 PESSDEMLSLVKN--THEFVETASSGNPLDFFPILRY 244
>M31667-1|AAA52163.1| 515|Homo sapiens CYP1A2 protein.
Length = 515
Score = 71.3 bits (167), Expect = 4e-12
Identities = 58/217 (26%), Positives = 106/217 (48%), Gaps = 13/217 (5%)
Frame = +1
Query: 103 RGLCYPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTG 282
+GL PP P P++G+++++ K HL SQ+YG++L +R+GS V+V++
Sbjct: 37 KGLKSPPEPWGWPLLGHVLTL------GKNPHLALSRMSQRYGDVLQIRIGSTPVLVLSR 90
Query: 283 IELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGY- 453
++ I++ V + F+GRPD + T+ + G+ L GP W RR L F
Sbjct: 91 LDTIRQALVRQGDDFKGRPDLYTSTLITDGQSLTFSTDSGPVWAARRRLAQNALNTFSIA 150
Query: 454 ------NSRFMNVYIGEECEALV---QLRFADAGEPILVNQMFHITIVNILWRLVAGKRY 606
+S ++ ++ +E +AL+ Q A G NQ+ +++ N++ + G+ +
Sbjct: 151 SDPASSSSCYLEEHVSKEAKALISRLQELMAGPGHFDPYNQVV-VSVANVIGAMCFGQHF 209
Query: 607 -DLXDQRLKKLCNLVMRLFKLXDMSGGILNFLPFLXH 714
+ D+ L + N F SG L+F P L +
Sbjct: 210 PESSDEMLSLVKN--THEFVETASSGNPLDFFPILRY 244
>DQ022432-1|AAY26399.1| 516|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 2 protein.
Length = 516
Score = 71.3 bits (167), Expect = 4e-12
Identities = 58/217 (26%), Positives = 106/217 (48%), Gaps = 13/217 (5%)
Frame = +1
Query: 103 RGLCYPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTG 282
+GL PP P P++G+++++ K HL SQ+YG++L +R+GS V+V++
Sbjct: 37 KGLKSPPEPWGWPLLGHVLTL------GKNPHLALSRMSQRYGDVLQIRIGSTPVLVLSR 90
Query: 283 IELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGY- 453
++ I++ V + F+GRPD + T+ + G+ L GP W RR L F
Sbjct: 91 LDTIRQALVRQGDDFKGRPDLYTSTLITDGQSLTFSTDSGPVWAARRRLAQNALNTFSIA 150
Query: 454 ------NSRFMNVYIGEECEALV---QLRFADAGEPILVNQMFHITIVNILWRLVAGKRY 606
+S ++ ++ +E +AL+ Q A G NQ+ +++ N++ + G+ +
Sbjct: 151 SDPASSSSCYLEEHVSKEAKALISRLQELMAGPGHFDPYNQVV-VSVANVIGAMCFGQHF 209
Query: 607 -DLXDQRLKKLCNLVMRLFKLXDMSGGILNFLPFLXH 714
+ D+ L + N F SG L+F P L +
Sbjct: 210 PESSDEMLSLVKN--THEFVETASSGNPLDFFPILRY 244
>BC067429-1|AAH67429.1| 516|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 2 protein.
Length = 516
Score = 71.3 bits (167), Expect = 4e-12
Identities = 58/217 (26%), Positives = 106/217 (48%), Gaps = 13/217 (5%)
Frame = +1
Query: 103 RGLCYPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTG 282
+GL PP P P++G+++++ K HL SQ+YG++L +R+GS V+V++
Sbjct: 37 KGLKSPPEPWGWPLLGHVLTL------GKNPHLALSRMSQRYGDVLQIRIGSTPVLVLSR 90
Query: 283 IELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGY- 453
++ I++ V + F+GRPD + T+ + G+ L GP W RR L F
Sbjct: 91 LDTIRQALVRQGDDFKGRPDLYTSTLITDGQSLTFSTDSGPVWAARRRLAQNALNTFSIA 150
Query: 454 ------NSRFMNVYIGEECEALV---QLRFADAGEPILVNQMFHITIVNILWRLVAGKRY 606
+S ++ ++ +E +AL+ Q A G NQ+ +++ N++ + G+ +
Sbjct: 151 SDPASSSSCYLEEHVSKEAKALISRLQELMAGPGHFDPYNQVV-VSVANVIGAMCFGQHF 209
Query: 607 -DLXDQRLKKLCNLVMRLFKLXDMSGGILNFLPFLXH 714
+ D+ L + N F SG L+F P L +
Sbjct: 210 PESSDEMLSLVKN--THEFVETASSGNPLDFFPILRY 244
>BC067428-1|AAH67428.1| 516|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 2 protein.
Length = 516
Score = 71.3 bits (167), Expect = 4e-12
Identities = 58/217 (26%), Positives = 106/217 (48%), Gaps = 13/217 (5%)
Frame = +1
Query: 103 RGLCYPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTG 282
+GL PP P P++G+++++ K HL SQ+YG++L +R+GS V+V++
Sbjct: 37 KGLKSPPEPWGWPLLGHVLTL------GKNPHLALSRMSQRYGDVLQIRIGSTPVLVLSR 90
Query: 283 IELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGY- 453
++ I++ V + F+GRPD + T+ + G+ L GP W RR L F
Sbjct: 91 LDTIRQALVRQGDDFKGRPDLYTSTLITDGQSLTFSTDSGPVWAARRRLAQNALNTFSIA 150
Query: 454 ------NSRFMNVYIGEECEALV---QLRFADAGEPILVNQMFHITIVNILWRLVAGKRY 606
+S ++ ++ +E +AL+ Q A G NQ+ +++ N++ + G+ +
Sbjct: 151 SDPASSSSCYLEEHVSKEAKALISRLQELMAGPGHFDPYNQVV-VSVANVIGAMCFGQHF 209
Query: 607 -DLXDQRLKKLCNLVMRLFKLXDMSGGILNFLPFLXH 714
+ D+ L + N F SG L+F P L +
Sbjct: 210 PESSDEMLSLVKN--THEFVETASSGNPLDFFPILRY 244
>BC067426-1|AAH67426.1| 516|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 2 protein.
Length = 516
Score = 71.3 bits (167), Expect = 4e-12
Identities = 58/217 (26%), Positives = 106/217 (48%), Gaps = 13/217 (5%)
Frame = +1
Query: 103 RGLCYPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTG 282
+GL PP P P++G+++++ K HL SQ+YG++L +R+GS V+V++
Sbjct: 37 KGLKSPPEPWGWPLLGHVLTL------GKNPHLALSRMSQRYGDVLQIRIGSTPVLVLSR 90
Query: 283 IELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGY- 453
++ I++ V + F+GRPD + T+ + G+ L GP W RR L F
Sbjct: 91 LDTIRQALVRQGDDFKGRPDLYTSTLITDGQSLTFSTDSGPVWAARRRLAQNALNTFSIA 150
Query: 454 ------NSRFMNVYIGEECEALV---QLRFADAGEPILVNQMFHITIVNILWRLVAGKRY 606
+S ++ ++ +E +AL+ Q A G NQ+ +++ N++ + G+ +
Sbjct: 151 SDPASSSSCYLEEHVSKEAKALISRLQELMAGPGHFDPYNQVV-VSVANVIGAMCFGQHF 209
Query: 607 -DLXDQRLKKLCNLVMRLFKLXDMSGGILNFLPFLXH 714
+ D+ L + N F SG L+F P L +
Sbjct: 210 PESSDEMLSLVKN--THEFVETASSGNPLDFFPILRY 244
>BC067425-1|AAH67425.1| 516|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 2 protein.
Length = 516
Score = 71.3 bits (167), Expect = 4e-12
Identities = 58/217 (26%), Positives = 106/217 (48%), Gaps = 13/217 (5%)
Frame = +1
Query: 103 RGLCYPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTG 282
+GL PP P P++G+++++ K HL SQ+YG++L +R+GS V+V++
Sbjct: 37 KGLKSPPEPWGWPLLGHVLTL------GKNPHLALSRMSQRYGDVLQIRIGSTPVLVLSR 90
Query: 283 IELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGY- 453
++ I++ V + F+GRPD + T+ + G+ L GP W RR L F
Sbjct: 91 LDTIRQALVRQGDDFKGRPDLYTSTLITDGQSLTFSTDSGPVWAARRRLAQNALNTFSIA 150
Query: 454 ------NSRFMNVYIGEECEALV---QLRFADAGEPILVNQMFHITIVNILWRLVAGKRY 606
+S ++ ++ +E +AL+ Q A G NQ+ +++ N++ + G+ +
Sbjct: 151 SDPASSSSCYLEEHVSKEAKALISRLQELMAGPGHFDPYNQVV-VSVANVIGAMCFGQHF 209
Query: 607 -DLXDQRLKKLCNLVMRLFKLXDMSGGILNFLPFLXH 714
+ D+ L + N F SG L+F P L +
Sbjct: 210 PESSDEMLSLVKN--THEFVETASSGNPLDFFPILRY 244
>BC067424-1|AAH67424.1| 516|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 2 protein.
Length = 516
Score = 71.3 bits (167), Expect = 4e-12
Identities = 58/217 (26%), Positives = 106/217 (48%), Gaps = 13/217 (5%)
Frame = +1
Query: 103 RGLCYPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTG 282
+GL PP P P++G+++++ K HL SQ+YG++L +R+GS V+V++
Sbjct: 37 KGLKSPPEPWGWPLLGHVLTL------GKNPHLALSRMSQRYGDVLQIRIGSTPVLVLSR 90
Query: 283 IELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGY- 453
++ I++ V + F+GRPD + T+ + G+ L GP W RR L F
Sbjct: 91 LDTIRQALVRQGDDFKGRPDLYTSTLITDGQSLTFSTDSGPVWAARRRLAQNALNTFSIA 150
Query: 454 ------NSRFMNVYIGEECEALV---QLRFADAGEPILVNQMFHITIVNILWRLVAGKRY 606
+S ++ ++ +E +AL+ Q A G NQ+ +++ N++ + G+ +
Sbjct: 151 SDPASSSSCYLEEHVSKEAKALISRLQELMAGPGHFDPYNQVV-VSVANVIGAMCFGQHF 209
Query: 607 -DLXDQRLKKLCNLVMRLFKLXDMSGGILNFLPFLXH 714
+ D+ L + N F SG L+F P L +
Sbjct: 210 PESSDEMLSLVKN--THEFVETASSGNPLDFFPILRY 244
>AF253322-2|AAK25728.1| 516|Homo sapiens cytochrome P450 protein.
Length = 516
Score = 71.3 bits (167), Expect = 4e-12
Identities = 58/217 (26%), Positives = 106/217 (48%), Gaps = 13/217 (5%)
Frame = +1
Query: 103 RGLCYPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTG 282
+GL PP P P++G+++++ K HL SQ+YG++L +R+GS V+V++
Sbjct: 37 KGLKSPPEPWGWPLLGHVLTL------GKNPHLALSRMSQRYGDVLQIRIGSTPVLVLSR 90
Query: 283 IELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGY- 453
++ I++ V + F+GRPD + T+ + G+ L GP W RR L F
Sbjct: 91 LDTIRQALVRQGDDFKGRPDLYTSTLITDGQSLTFSTDSGPVWAARRRLAQNALNTFSIA 150
Query: 454 ------NSRFMNVYIGEECEALV---QLRFADAGEPILVNQMFHITIVNILWRLVAGKRY 606
+S ++ ++ +E +AL+ Q A G NQ+ +++ N++ + G+ +
Sbjct: 151 SDPASSSSCYLEEHVSKEAKALISRLQELMAGPGHFDPYNQVV-VSVANVIGAMCFGQHF 209
Query: 607 -DLXDQRLKKLCNLVMRLFKLXDMSGGILNFLPFLXH 714
+ D+ L + N F SG L+F P L +
Sbjct: 210 PESSDEMLSLVKN--THEFVETASSGNPLDFFPILRY 244
>AF182274-1|AAF13599.1| 516|Homo sapiens cytochrome P450-1A2
protein.
Length = 516
Score = 70.1 bits (164), Expect = 8e-12
Identities = 58/217 (26%), Positives = 105/217 (48%), Gaps = 13/217 (5%)
Frame = +1
Query: 103 RGLCYPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTG 282
+GL PP P P++G+++++ K HL SQ+YG++L +R+GS V+V++
Sbjct: 37 KGLKSPPEPWGWPLLGHVLTL------GKNPHLALSRMSQRYGDVLQIRIGSTPVLVLSR 90
Query: 283 IELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGY- 453
++ I++ V + F+GRPD + T+ + G+ L GP W RR L F
Sbjct: 91 LDTIRQALVRQGDDFKGRPDLYTSTLITDGQSLTFSTDSGPVWAARRRLAQNALNTFSIA 150
Query: 454 ------NSRFMNVYIGEECEALV---QLRFADAGEPILVNQMFHITIVNILWRLVAGKRY 606
+S ++ ++ +E AL+ Q A G NQ+ +++ N++ + G+ +
Sbjct: 151 SDPASSSSCYLEEHVSKEAMALISRLQELMAGPGHFDPYNQVV-VSVANVIGAMCFGQHF 209
Query: 607 -DLXDQRLKKLCNLVMRLFKLXDMSGGILNFLPFLXH 714
+ D+ L + N F SG L+F P L +
Sbjct: 210 PESSDEMLSLVKN--THEFVETASSGNPLDFFPILRY 244
>BC025761-1|AAH25761.2| 490|Homo sapiens cytochrome P450, family 2,
subfamily W, polypeptide 1 protein.
Length = 490
Score = 69.3 bits (162), Expect = 1e-11
Identities = 56/202 (27%), Positives = 89/202 (44%), Gaps = 4/202 (1%)
Frame = +1
Query: 115 YPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELI 294
+PPGP PLP+VGNL + + L S++YG + + LG VV+TG E +
Sbjct: 31 WPPGPRPLPLVGNLHLLRLSQQDRSLMEL-----SERYGPVFTVHLGRQKTVVLTGFEAV 85
Query: 295 KEV---SNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRF 465
KE +E+ + P F ++ G G+ FS G W R+F ++ L + G
Sbjct: 86 KEALAGPGQELADRPPIAIFQLIQRGG---GIFFSSGARWRAARQFTVRALHSLGVGREP 142
Query: 466 MNVYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCNL 645
+ I +E + L G P + + NI + L+ G+R+D D L L
Sbjct: 143 VADKILQELKCLSGQLDGYRGRPFPL-ALLGWAPSNITFALLFGRRFDYRDPVFVSLLGL 201
Query: 646 VMRLFKLXDMSG-GILNFLPFL 708
+ + L G + N P+L
Sbjct: 202 IDEVMVLLGSPGLQLFNVYPWL 223
>X13929-1|CAA32117.1| 448|Homo sapiens P-450 IIA3 protein (1 is 3rd
base in codon) protein.
Length = 448
Score = 68.9 bits (161), Expect = 2e-11
Identities = 48/160 (30%), Positives = 75/160 (46%), Gaps = 2/160 (1%)
Frame = +1
Query: 217 SQKYGNLLGLRLGSINVVVVTGIELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFS 390
S++YG + + LG VVV+ G + ++E V E F GR G T K G+VFS
Sbjct: 16 SERYGPVFTIHLGPRRVVVLCGHDAVREALVDQAEEFSGR--GEQATFDWVFKGYGVVFS 73
Query: 391 DGPTWHRTRRFVLKYLKNFGYNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIV 570
+G + RRF + L++FG R + I EE L+ G I T+
Sbjct: 74 NGERAKQLRRFSIATLRDFGVGKRGIEERIQEEAGFLIDALRGTGGANIDPTFFLSRTVS 133
Query: 571 NILWRLVAGKRYDLXDQRLKKLCNLVMRLFKLXDMSGGIL 690
N++ +V G R+D D+ L +++ +F+ S G L
Sbjct: 134 NVISSIVFGDRFDYKDKEFLSLLRMMLGIFQFTSTSTGQL 173
>L00389-1|AAA35738.1| 516|Homo sapiens protein ( Human cytochrome
P-450 4 gene, exon 7, and three Alu repeats in the 3'
flank. ).
Length = 516
Score = 68.9 bits (161), Expect = 2e-11
Identities = 57/217 (26%), Positives = 105/217 (48%), Gaps = 13/217 (5%)
Frame = +1
Query: 103 RGLCYPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTG 282
+GL PP P P++G+++++ K HL SQ+YG++L + +GS V+V++
Sbjct: 37 KGLKSPPEPWGWPLLGHVLTL------GKNPHLALSRMSQRYGDVLQISIGSTPVLVLSR 90
Query: 283 IELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGY- 453
++ I++ V + F+GRPD + T+ + G+ L GP W RR L F
Sbjct: 91 LDTIRQALVRQGDDFKGRPDLYTSTLITDGQSLTFSTDSGPVWAARRRLAQNALNTFSIA 150
Query: 454 ------NSRFMNVYIGEECEALV---QLRFADAGEPILVNQMFHITIVNILWRLVAGKRY 606
+S ++ ++ +E +AL+ Q A G NQ+ +++ N++ + G+ +
Sbjct: 151 SDPASSSSCYLEEHVSKEAKALISRLQELMAGPGHFDPYNQVV-VSVANVIGAMCFGQHF 209
Query: 607 -DLXDQRLKKLCNLVMRLFKLXDMSGGILNFLPFLXH 714
+ D+ L + N F SG L+F P L +
Sbjct: 210 PESSDEMLSLVKN--THEFVETASSGNPLDFFPILRY 244
>BC067427-1|AAH67427.1| 516|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 2 protein.
Length = 516
Score = 68.5 bits (160), Expect = 3e-11
Identities = 57/217 (26%), Positives = 105/217 (48%), Gaps = 13/217 (5%)
Frame = +1
Query: 103 RGLCYPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTG 282
+GL PP P P++G+++++ K HL SQ+YG++L +R+ S V+V++
Sbjct: 37 KGLKSPPEPWGWPLLGHVLTL------GKNPHLALSRMSQRYGDVLQIRIDSTPVLVLSR 90
Query: 283 IELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGY- 453
++ I++ V + F+GRPD + T+ + G+ L GP W RR L F
Sbjct: 91 LDTIRQALVRQGDDFKGRPDLYTSTLITDGQSLTFSTDSGPVWAARRRLAQNALNTFSIA 150
Query: 454 ------NSRFMNVYIGEECEALV---QLRFADAGEPILVNQMFHITIVNILWRLVAGKRY 606
+S ++ ++ +E +AL+ Q A G NQ+ +++ N++ + G+ +
Sbjct: 151 SDPASSSSCYLEEHVSKEAKALISRLQELMAGPGHFDPYNQVV-VSVANVIGAMCFGQHF 209
Query: 607 -DLXDQRLKKLCNLVMRLFKLXDMSGGILNFLPFLXH 714
+ D+ L + N F SG L+F P L +
Sbjct: 210 PESSDEMLSLVKN--THEFVETASSGNPLDFFPILRY 244
>L07093-1|AAA36660.1| 468|Homo sapiens cytochrome P450 protein.
Length = 468
Score = 68.1 bits (159), Expect = 3e-11
Identities = 45/145 (31%), Positives = 66/145 (45%), Gaps = 2/145 (1%)
Frame = +1
Query: 208 QSWSQKYGNLLGLRLGSINVVVVTGIELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGL 381
Q S+ YG + L G +VV+ G E++KE + E F GR G F + G+
Sbjct: 33 QQLSKIYGPVFTLYFGLERMVVLHGYEVVKEALIDLGEEFSGR--GHFPLAERANRGFGI 90
Query: 382 VFSDGPTWHRTRRFVLKYLKNFGYNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHI 561
VFS+G W RRF L L+NFG R + + EE LV+ P +
Sbjct: 91 VFSNGKRWKEIRRFSLMTLRNFGMGKRSIEDRVQEEARCLVEELRKTKASPCDPTFILGC 150
Query: 562 TIVNILWRLVAGKRYDLXDQRLKKL 636
N++ ++ KR+D DQ+ L
Sbjct: 151 APCNVICSIIFQKRFDYKDQQFLNL 175
>BC033691-1|AAH33691.1| 504|Homo sapiens cytochrome P450, family 2,
subfamily S, polypeptide 1 protein.
Length = 504
Score = 66.1 bits (154), Expect = 1e-10
Identities = 50/174 (28%), Positives = 80/174 (45%), Gaps = 3/174 (1%)
Frame = +1
Query: 118 PPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSIN-VVVVTGIELI 294
PPGPTPLP++GNL+ + R + + + S+KYG + + LG VVV+ G E +
Sbjct: 33 PPGPTPLPLLGNLLQL----RPGALYSGLMRL-SKKYGPVFTIYLGPWRPVVVLVGQEAV 87
Query: 295 KEV--SNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFM 468
+E E F GR G + G+ FS+G W + R+F + L++ G R
Sbjct: 88 REALGGQAEEFSGR--GTVAMLEGTFDGHGVFFSNGERWRQLRKFTMLALRDLGMGKREG 145
Query: 469 NVYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLK 630
I E LV+ G P + + N++ L+ G R+ D+ +
Sbjct: 146 EELIQAEARCLVETFQGTEGRPFDPSLLLAQATSNVVCSLLFGLRFSYEDKEFQ 199
>AY358603-1|AAQ88966.1| 504|Homo sapiens Cytochrome p450 protein.
Length = 504
Score = 66.1 bits (154), Expect = 1e-10
Identities = 50/174 (28%), Positives = 80/174 (45%), Gaps = 3/174 (1%)
Frame = +1
Query: 118 PPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSIN-VVVVTGIELI 294
PPGPTPLP++GNL+ + R + + + S+KYG + + LG VVV+ G E +
Sbjct: 33 PPGPTPLPLLGNLLQL----RPGALYSGLMRL-SKKYGPVFTIYLGPWRPVVVLVGQEAV 87
Query: 295 KEV--SNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFM 468
+E E F GR G + G+ FS+G W + R+F + L++ G R
Sbjct: 88 REALGGQAEEFSGR--GTVAMLEGTFDGHGVFFSNGERWRQLRKFTMLALRDLGMGKREG 145
Query: 469 NVYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLK 630
I E LV+ G P + + N++ L+ G R+ D+ +
Sbjct: 146 EELIQAEARCLVETFQGTEGRPFDPSLLLAQATSNVVCSLLFGLRFSYEDKEFQ 199
>AK027605-1|BAB55227.1| 564|Homo sapiens protein ( Homo sapiens
cDNA FLJ14699 fis, clone NT2RP2006571, moderately
similar to CYTOCHROME P450 2G1 (EC 1.14.14.1). ).
Length = 564
Score = 66.1 bits (154), Expect = 1e-10
Identities = 50/174 (28%), Positives = 80/174 (45%), Gaps = 3/174 (1%)
Frame = +1
Query: 118 PPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSIN-VVVVTGIELI 294
PPGPTPLP++GNL+ + R + + + S+KYG + + LG VVV+ G E +
Sbjct: 33 PPGPTPLPLLGNLLQL----RPGALYSGLMRL-SKKYGPVFTIYLGPWRPVVVLVGQEAV 87
Query: 295 KEV--SNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFM 468
+E E F GR G + G+ FS+G W + R+F + L++ G R
Sbjct: 88 REALGGQAEEFSGR--GTVAMLEGTFDGHGVFFSNGERWRQLRKFTMLALRDLGMGKREG 145
Query: 469 NVYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLK 630
I E LV+ G P + + N++ L+ G R+ D+ +
Sbjct: 146 EELIQAEARCLVETFQGTEGRPFDPSLLLAQATSNVVCSLLFGLRFSYEDKEFQ 199
>AF335278-1|AAK13498.1| 504|Homo sapiens cytochrome P450 2S1
protein.
Length = 504
Score = 66.1 bits (154), Expect = 1e-10
Identities = 50/174 (28%), Positives = 80/174 (45%), Gaps = 3/174 (1%)
Frame = +1
Query: 118 PPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSIN-VVVVTGIELI 294
PPGPTPLP++GNL+ + R + + + S+KYG + + LG VVV+ G E +
Sbjct: 33 PPGPTPLPLLGNLLQL----RPGALYSGLMRL-SKKYGPVFTIYLGPWRPVVVLVGQEAV 87
Query: 295 KEV--SNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFM 468
+E E F GR G + G+ FS+G W + R+F + L++ G R
Sbjct: 88 REALGGQAEEFSGR--GTVAMLEGTFDGHGVFFSNGERWRQLRKFTMLALRDLGMGKREG 145
Query: 469 NVYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLK 630
I E LV+ G P + + N++ L+ G R+ D+ +
Sbjct: 146 EELIQAEARCLVETFQGTEGRPFDPSLLLAQATSNVVCSLLFGLRFSYEDKEFQ 199
>M24499-1|AAA36403.1| 373|Homo sapiens cytochrome P450db1 protein.
Length = 373
Score = 58.0 bits (134), Expect = 4e-08
Identities = 33/115 (28%), Positives = 52/115 (45%), Gaps = 1/115 (0%)
Frame = +1
Query: 394 GPTWHRTRRFVLKYLKNFGYNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIVN 573
GP W RRF + L+N G + + ++ EE L +G P N + + N
Sbjct: 1 GPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSN 60
Query: 574 ILWRLVAGKRYDLXDQRLKKLCNLVMR-LFKLXDMSGGILNFLPFLXHFIPRLIG 735
++ L G+R++ D R +L +L L + +LN +P L H IP L G
Sbjct: 61 VIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLH-IPALAG 114
>M33189-1|AAA35737.1| 500|Homo sapiens protein ( Human debrisoquine
4-hydroxylase mutant allele (CYP2D6-MA1) gene, complete
cds. ).
Length = 500
Score = 57.6 bits (133), Expect = 5e-08
Identities = 61/230 (26%), Positives = 100/230 (43%), Gaps = 13/230 (5%)
Frame = +1
Query: 85 IISRRHRGLC-YPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSI 261
++ RR R Y PGP PLP +GNL+ V +++ + C + +++G++ L+L
Sbjct: 22 LMHRRQRWAARYSPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWT 76
Query: 262 NVVVVTGIELIKE--VSNREVFEGRP-----DGFFYTMRSFGKKLGLVFSDGPTWHRTRR 420
VVV+ G+ ++E V+ E RP + RS GK+ G+ G W R R
Sbjct: 77 PVVVLNGLAAVREAMVTRGEDTADRPPVPITQILGFGPRSQGKQRGV---PGALWARVAR 133
Query: 421 ---FVLKYLKNFGYNSRFMNVYIGEECEALVQLRFAD-AGEPILVNQMFHITIVNILWRL 588
+ +L G +G+ L R P N + + N++ L
Sbjct: 134 AEALLRLHLAQLGPGQEVAGA-VGDRGGRLPLCRLRQPLRRPFRPNGLLDKAVSNVIASL 192
Query: 589 VAGKRYDLXDQRLKKLCNLVMR-LFKLXDMSGGILNFLPFLXHFIPRLIG 735
G+R++ D R +L +L L + +LN +P L H IP L G
Sbjct: 193 TCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLH-IPALAG 241
>AK000366-1|BAA91114.1| 408|Homo sapiens protein ( Homo sapiens
cDNA FLJ20359 fis, clone HEP16626. ).
Length = 408
Score = 53.2 bits (122), Expect = 1e-06
Identities = 44/168 (26%), Positives = 73/168 (43%), Gaps = 4/168 (2%)
Frame = +1
Query: 217 SQKYGNLLGLRLGSINVVVVTGIELIKEV---SNREVFEGRPDGFFYTMRSFGKKLGLVF 387
S++YG + + LG VV+TG E +KE +E+ + P F ++ G G+ F
Sbjct: 4 SERYGPVFTVHLGRQKTVVLTGFEAVKEALAGPGQELADRPPIAIFQLIQRGG---GIFF 60
Query: 388 SDGPTWHRTRRFVLKYLKNFGYNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITI 567
S G W R+F ++ L + G + I +E + L G P + +
Sbjct: 61 SSGARWRAARQFTVRALHSLGVGREPVADKILQELKCLSGQLDGYRGRPFPL-ALLGWAP 119
Query: 568 VNILWRLVAGKRYDLXDQRLKKLCNLVMRLFKLXDMSG-GILNFLPFL 708
NI + L+ G+R+D D L L+ + L G + N P+L
Sbjct: 120 SNITFALLFGRRFDYRDPVFVSLLGLIDEVMVLLGSPGLQLFNVHPWL 167
>M63871-1|AAA59984.1| 508|Homo sapiens CYP17 protein.
Length = 508
Score = 52.4 bits (120), Expect = 2e-06
Identities = 47/186 (25%), Positives = 79/186 (42%), Gaps = 3/186 (1%)
Frame = +1
Query: 94 RRHRGLCYPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 273
RR G YP LP+VG+L + R H+ ++ +KYG + +R+G+ V+
Sbjct: 20 RRWPGAKYPKSLLSLPLVGSLPFL---PRHGHMHNNFFKL-QKKYGPIYSVRMGTKTTVI 75
Query: 274 VTGIELIKEV--SNREVFEGRPDGFFYTMRSFGKKLGLVFSD-GPTWHRTRRFVLKYLKN 444
V +L KEV + F GRP + S +K G+ F+D G W RR +
Sbjct: 76 VGHHQLAKEVLIKKGKDFSGRPQMATLDIASNNRK-GIAFADSGAHWQLHRRLAMATFAL 134
Query: 445 FGYNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQR 624
F + + I +E L + G+ I ++ + + N++ + Y D
Sbjct: 135 FKDGDQKLEKIICQEISTLCDMLATHNGQSIDISFPVFVAVTNVISLICFNTSYKNGDPE 194
Query: 625 LKKLCN 642
L + N
Sbjct: 195 LNVIQN 200
>M19489-1|AAA36405.1| 508|Homo sapiens CYP17 protein.
Length = 508
Score = 52.4 bits (120), Expect = 2e-06
Identities = 47/186 (25%), Positives = 79/186 (42%), Gaps = 3/186 (1%)
Frame = +1
Query: 94 RRHRGLCYPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 273
RR G YP LP+VG+L + R H+ ++ +KYG + +R+G+ V+
Sbjct: 20 RRWPGAKYPKSLLSLPLVGSLPFL---PRHGHMHNNFFKL-QKKYGPIYSVRMGTKTTVI 75
Query: 274 VTGIELIKEV--SNREVFEGRPDGFFYTMRSFGKKLGLVFSD-GPTWHRTRRFVLKYLKN 444
V +L KEV + F GRP + S +K G+ F+D G W RR +
Sbjct: 76 VGHHQLAKEVLIKKGKDFSGRPQMATLDIASNNRK-GIAFADSGAHWQLHRRLAMATFAL 134
Query: 445 FGYNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQR 624
F + + I +E L + G+ I ++ + + N++ + Y D
Sbjct: 135 FKDGDQKLEKIICQEISTLCDMLATHNGQSIDISFPVFVAVTNVISLICFNTSYKNGDPE 194
Query: 625 LKKLCN 642
L + N
Sbjct: 195 LNVIQN 200
>M14564-1|AAA52151.1| 508|Homo sapiens CYP17 protein.
Length = 508
Score = 52.0 bits (119), Expect = 2e-06
Identities = 47/186 (25%), Positives = 79/186 (42%), Gaps = 3/186 (1%)
Frame = +1
Query: 94 RRHRGLCYPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 273
RR G YP LP+VG+L + R H+ ++ +KYG + +R+G+ V+
Sbjct: 20 RRCPGAKYPKSLLSLPLVGSLPFL---PRHGHMHNNFFKL-QKKYGPIYSVRMGTKTTVI 75
Query: 274 VTGIELIKEV--SNREVFEGRPDGFFYTMRSFGKKLGLVFSD-GPTWHRTRRFVLKYLKN 444
V +L KEV + F GRP + S +K G+ F+D G W RR +
Sbjct: 76 VGHHQLAKEVLIKKGKDFSGRPQMATLDIASNNRK-GIAFADSGAHWQLHRRLAMATFAL 134
Query: 445 FGYNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQR 624
F + + I +E L + G+ I ++ + + N++ + Y D
Sbjct: 135 FKDGDQKLEKIICQEISTLCDMLATHNGQSIDISFPVFVAVTNVISLICFNTSYKNGDPE 194
Query: 625 LKKLCN 642
L + N
Sbjct: 195 LNVIQN 200
>DQ530598-1|ABF50972.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 52.0 bits (119), Expect = 2e-06
Identities = 47/186 (25%), Positives = 79/186 (42%), Gaps = 3/186 (1%)
Frame = +1
Query: 94 RRHRGLCYPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 273
RR G YP LP+VG+L + R H+ ++ +KYG + +R+G+ V+
Sbjct: 20 RRCPGAKYPKSLLSLPLVGSLPFL---PRHGHMHNNFFKL-QKKYGPIYSVRMGTKTTVI 75
Query: 274 VTGIELIKEV--SNREVFEGRPDGFFYTMRSFGKKLGLVFSD-GPTWHRTRRFVLKYLKN 444
V +L KEV + F GRP + S +K G+ F+D G W RR +
Sbjct: 76 VGHHQLAKEVLIKKGKDFSGRPQMATLDIASNNRK-GIAFADSGAHWQLHRRLAMATFAL 134
Query: 445 FGYNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQR 624
F + + I +E L + G+ I ++ + + N++ + Y D
Sbjct: 135 FKDGDQKLEKIICQEISTLCDMLATHNGQSIDISFPVFVAVTNVISLICFNTSYKNGDPE 194
Query: 625 LKKLCN 642
L + N
Sbjct: 195 LNVIQN 200
>BT020000-1|AAV38803.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 52.0 bits (119), Expect = 2e-06
Identities = 47/186 (25%), Positives = 79/186 (42%), Gaps = 3/186 (1%)
Frame = +1
Query: 94 RRHRGLCYPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 273
RR G YP LP+VG+L + R H+ ++ +KYG + +R+G+ V+
Sbjct: 20 RRCPGAKYPKSLLSLPLVGSLPFL---PRHGHMHNNFFKL-QKKYGPIYSVRMGTKTTVI 75
Query: 274 VTGIELIKEV--SNREVFEGRPDGFFYTMRSFGKKLGLVFSD-GPTWHRTRRFVLKYLKN 444
V +L KEV + F GRP + S +K G+ F+D G W RR +
Sbjct: 76 VGHHQLAKEVLIKKGKDFSGRPQMATLDIASNNRK-GIAFADSGAHWQLHRRLAMATFAL 134
Query: 445 FGYNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQR 624
F + + I +E L + G+ I ++ + + N++ + Y D
Sbjct: 135 FKDGDQKLEKIICQEISTLCDMLATHNGQSIDISFPVFVAVTNVISLICFNTSYKNGDPE 194
Query: 625 LKKLCN 642
L + N
Sbjct: 195 LNVIQN 200
>BC063388-1|AAH63388.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 52.0 bits (119), Expect = 2e-06
Identities = 47/186 (25%), Positives = 79/186 (42%), Gaps = 3/186 (1%)
Frame = +1
Query: 94 RRHRGLCYPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 273
RR G YP LP+VG+L + R H+ ++ +KYG + +R+G+ V+
Sbjct: 20 RRCPGAKYPKSLLSLPLVGSLPFL---PRHGHMHNNFFKL-QKKYGPIYSVRMGTKTTVI 75
Query: 274 VTGIELIKEV--SNREVFEGRPDGFFYTMRSFGKKLGLVFSD-GPTWHRTRRFVLKYLKN 444
V +L KEV + F GRP + S +K G+ F+D G W RR +
Sbjct: 76 VGHHQLAKEVLIKKGKDFSGRPQMATLDIASNNRK-GIAFADSGAHWQLHRRLAMATFAL 134
Query: 445 FGYNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQR 624
F + + I +E L + G+ I ++ + + N++ + Y D
Sbjct: 135 FKDGDQKLEKIICQEISTLCDMLATHNGQSIDISFPVFVAVTNVISLICFNTSYKNGDPE 194
Query: 625 LKKLCN 642
L + N
Sbjct: 195 LNVIQN 200
>BC062997-1|AAH62997.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 52.0 bits (119), Expect = 2e-06
Identities = 47/186 (25%), Positives = 79/186 (42%), Gaps = 3/186 (1%)
Frame = +1
Query: 94 RRHRGLCYPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 273
RR G YP LP+VG+L + R H+ ++ +KYG + +R+G+ V+
Sbjct: 20 RRCPGAKYPKSLLSLPLVGSLPFL---PRHGHMHNNFFKL-QKKYGPIYSVRMGTKTTVI 75
Query: 274 VTGIELIKEV--SNREVFEGRPDGFFYTMRSFGKKLGLVFSD-GPTWHRTRRFVLKYLKN 444
V +L KEV + F GRP + S +K G+ F+D G W RR +
Sbjct: 76 VGHHQLAKEVLIKKGKDFSGRPQMATLDIASNNRK-GIAFADSGAHWQLHRRLAMATFAL 134
Query: 445 FGYNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQR 624
F + + I +E L + G+ I ++ + + N++ + Y D
Sbjct: 135 FKDGDQKLEKIICQEISTLCDMLATHNGQSIDISFPVFVAVTNVISLICFNTSYKNGDPE 194
Query: 625 LKKLCN 642
L + N
Sbjct: 195 LNVIQN 200
>AL358790-3|CAI52498.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 52.0 bits (119), Expect = 2e-06
Identities = 47/186 (25%), Positives = 79/186 (42%), Gaps = 3/186 (1%)
Frame = +1
Query: 94 RRHRGLCYPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 273
RR G YP LP+VG+L + R H+ ++ +KYG + +R+G+ V+
Sbjct: 20 RRCPGAKYPKSLLSLPLVGSLPFL---PRHGHMHNNFFKL-QKKYGPIYSVRMGTKTTVI 75
Query: 274 VTGIELIKEV--SNREVFEGRPDGFFYTMRSFGKKLGLVFSD-GPTWHRTRRFVLKYLKN 444
V +L KEV + F GRP + S +K G+ F+D G W RR +
Sbjct: 76 VGHHQLAKEVLIKKGKDFSGRPQMATLDIASNNRK-GIAFADSGAHWQLHRRLAMATFAL 134
Query: 445 FGYNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQR 624
F + + I +E L + G+ I ++ + + N++ + Y D
Sbjct: 135 FKDGDQKLEKIICQEISTLCDMLATHNGQSIDISFPVFVAVTNVISLICFNTSYKNGDPE 194
Query: 625 LKKLCN 642
L + N
Sbjct: 195 LNVIQN 200
>M31153-1|AAA52140.1| 508|Homo sapiens CYP17 protein.
Length = 508
Score = 51.6 bits (118), Expect = 3e-06
Identities = 47/186 (25%), Positives = 79/186 (42%), Gaps = 3/186 (1%)
Frame = +1
Query: 94 RRHRGLCYPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 273
RR G YP LP+VG+L + R H+ ++ +KYG + +R+G+ V+
Sbjct: 20 RRCPGAKYPKSLLSLPLVGSLPFL---PRHGHMHNNFFKL-QKKYGPIYSVRMGTKTTVI 75
Query: 274 VTGIELIKEV--SNREVFEGRPDGFFYTMRSFGKKLGLVFSD-GPTWHRTRRFVLKYLKN 444
V +L KEV + F GRP + S +K G+ F+D G W RR +
Sbjct: 76 VGHHQLAKEVLIKKGKDFSGRPQMATLDIASNNRK-GIAFADSGAHWQLHRRLAMATFAL 134
Query: 445 FGYNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQR 624
F + + I +E L + G+ I ++ + + N++ + Y D
Sbjct: 135 FKDGDQKLEKIICQEISTLSDMLATHNGQSIDISFPVFVAVTNVISLICFNTSYKNGDPE 194
Query: 625 LKKLCN 642
L + N
Sbjct: 195 LNVIQN 200
>M21940-1|AAA52159.1| 383|Homo sapiens CYP2C protein.
Length = 383
Score = 51.2 bits (117), Expect = 4e-06
Identities = 32/116 (27%), Positives = 50/116 (43%), Gaps = 2/116 (1%)
Frame = +1
Query: 376 GLVFSDGPTWHRTRRFVLKYLKNFGYNSRFMNVYIGEECEALVQLRFADAGEPILVNQMF 555
G+VFS+G W RRF L L+NFG R + + EE LV+ P +
Sbjct: 4 GIVFSNGKKWKEIRRFSLMTLRNFGMGKRSIEDRVQEEARCLVEELRKTKASPCDPTFIL 63
Query: 556 HITIVNILWRLVAGKRYDLXDQRLKKLCNLVMRLFKLXDMSGGIL--NFLPFLXHF 717
N++ ++ KR+D DQ+ L + K+ + NF P + +F
Sbjct: 64 GCAPCNVICSIIFHKRFDYKDQQFLNLMEKLNENIKILSSPWIQICNNFSPIIDYF 119
>U56438-1|AAC50809.1| 543|Homo sapiens dioxin-inducible cytochrome
P450 protein.
Length = 543
Score = 50.4 bits (115), Expect = 7e-06
Identities = 48/216 (22%), Positives = 94/216 (43%), Gaps = 8/216 (3%)
Frame = +1
Query: 94 RRHRGLCYPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 273
RR + PPGP P++GN +V + HL + +++YG++ +RLGS +VV
Sbjct: 43 RRRQLRSAPPGPFAWPLIGNAAAV------GQAAHLSFARLARRYGDVFQIRLGSCPIVV 96
Query: 274 VTGIELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNF 447
+ G I + V F RP + + S G+ + W RR ++NF
Sbjct: 97 LNGERAIHQALVQQGSAFADRPAFASFRVVSGGRSMAFGHY-SEHWKVQRRAAHSMMRNF 155
Query: 448 ----GYNSRFMNVYIGEECEALVQLRFADAGEPILVN--QMFHITIVNILWRLVAGKRYD 609
+ + + ++ E LV L + + ++ + + + N++ + G RY
Sbjct: 156 FTRQPRSRQVLEGHVLSEARELVALLVRGSADGAFLDPRPLTVVAVANVMSAVCFGCRYS 215
Query: 610 LXDQRLKKLCNLVMRLFKLXDMSGGILNFLPFLXHF 717
D ++L + F +G +++ +P+L +F
Sbjct: 216 HDDPEFRELLS-HNEEFGRTVGAGSLVDVMPWLQYF 250
>U03688-1|AAA19567.1| 543|Homo sapiens cytochrome P450 protein.
Length = 543
Score = 50.4 bits (115), Expect = 7e-06
Identities = 48/216 (22%), Positives = 94/216 (43%), Gaps = 8/216 (3%)
Frame = +1
Query: 94 RRHRGLCYPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 273
RR + PPGP P++GN +V + HL + +++YG++ +RLGS +VV
Sbjct: 43 RRRQLRSAPPGPFAWPLIGNAAAV------GQAAHLSFARLARRYGDVFQIRLGSCPIVV 96
Query: 274 VTGIELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNF 447
+ G I + V F RP + + S G+ + W RR ++NF
Sbjct: 97 LNGERAIHQALVQQGSAFADRPAFASFRVVSGGRSMAFGHY-SEHWKVQRRAAHSMMRNF 155
Query: 448 ----GYNSRFMNVYIGEECEALVQLRFADAGEPILVN--QMFHITIVNILWRLVAGKRYD 609
+ + + ++ E LV L + + ++ + + + N++ + G RY
Sbjct: 156 FTRQPRSRQVLEGHVLSEARELVALLVRGSADGAFLDPRPLTVVAVANVMSAVCFGCRYS 215
Query: 610 LXDQRLKKLCNLVMRLFKLXDMSGGILNFLPFLXHF 717
D ++L + F +G +++ +P+L +F
Sbjct: 216 HDDPEFRELLS-HNEEFGRTVGAGSLVDVMPWLQYF 250
>DQ359216-1|ABC95161.1| 347|Homo sapiens dioxin-inducible
cytochrome P450 protein.
Length = 347
Score = 50.4 bits (115), Expect = 7e-06
Identities = 48/216 (22%), Positives = 94/216 (43%), Gaps = 8/216 (3%)
Frame = +1
Query: 94 RRHRGLCYPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 273
RR + PPGP P++GN +V + HL + +++YG++ +RLGS +VV
Sbjct: 43 RRRQLRSAPPGPFAWPLIGNAAAV------GQAAHLSFARLARRYGDVFQIRLGSCPIVV 96
Query: 274 VTGIELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNF 447
+ G I + V F RP + + S G+ + W RR ++NF
Sbjct: 97 LNGERAIHQALVQQGSAFADRPAFASFRVVSGGRSMAFGHY-SEHWKVQRRAAHSMMRNF 155
Query: 448 ----GYNSRFMNVYIGEECEALVQLRFADAGEPILVN--QMFHITIVNILWRLVAGKRYD 609
+ + + ++ E LV L + + ++ + + + N++ + G RY
Sbjct: 156 FTRQPRSRQVLEGHVLSEARELVALLVRGSADGAFLDPRPLTVVAVANVMSAVCFGCRYS 215
Query: 610 LXDQRLKKLCNLVMRLFKLXDMSGGILNFLPFLXHF 717
D ++L + F +G +++ +P+L +F
Sbjct: 216 HDDPEFRELLS-HNEEFGRTVGAGSLVDVMPWLQYF 250
>BT019979-1|AAV38782.1| 543|Homo sapiens cytochrome P450, family 1,
subfamily B, polypeptide 1 protein.
Length = 543
Score = 50.4 bits (115), Expect = 7e-06
Identities = 48/216 (22%), Positives = 94/216 (43%), Gaps = 8/216 (3%)
Frame = +1
Query: 94 RRHRGLCYPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 273
RR + PPGP P++GN +V + HL + +++YG++ +RLGS +VV
Sbjct: 43 RRRQLRSAPPGPFAWPLIGNAAAV------GQAAHLSFARLARRYGDVFQIRLGSCPIVV 96
Query: 274 VTGIELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNF 447
+ G I + V F RP + + S G+ + W RR ++NF
Sbjct: 97 LNGERAIHQALVQQGSAFADRPAFASFRVVSGGRSMAFGHY-SEHWKVQRRAAHSMMRNF 155
Query: 448 ----GYNSRFMNVYIGEECEALVQLRFADAGEPILVN--QMFHITIVNILWRLVAGKRYD 609
+ + + ++ E LV L + + ++ + + + N++ + G RY
Sbjct: 156 FTRQPRSRQVLEGHVLSEARELVALLVRGSADGAFLDPRPLTVVAVANVMSAVCFGCRYS 215
Query: 610 LXDQRLKKLCNLVMRLFKLXDMSGGILNFLPFLXHF 717
D ++L + F +G +++ +P+L +F
Sbjct: 216 HDDPEFRELLS-HNEEFGRTVGAGSLVDVMPWLQYF 250
>BC012049-1|AAH12049.1| 543|Homo sapiens cytochrome P450, family 1,
subfamily B, polypeptide 1 protein.
Length = 543
Score = 50.4 bits (115), Expect = 7e-06
Identities = 48/216 (22%), Positives = 94/216 (43%), Gaps = 8/216 (3%)
Frame = +1
Query: 94 RRHRGLCYPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 273
RR + PPGP P++GN +V + HL + +++YG++ +RLGS +VV
Sbjct: 43 RRRQLRSAPPGPFAWPLIGNAAAV------GQAAHLSFARLARRYGDVFQIRLGSCPIVV 96
Query: 274 VTGIELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNF 447
+ G I + V F RP + + S G+ + W RR ++NF
Sbjct: 97 LNGERAIHQALVQQGSAFADRPAFASFRVVSGGRSMAFGHY-SEHWKVQRRAAHSMMRNF 155
Query: 448 ----GYNSRFMNVYIGEECEALVQLRFADAGEPILVN--QMFHITIVNILWRLVAGKRYD 609
+ + + ++ E LV L + + ++ + + + N++ + G RY
Sbjct: 156 FTRQPRSRQVLEGHVLSEARELVALLVRGSADGAFLDPRPLTVVAVANVMSAVCFGCRYS 215
Query: 610 LXDQRLKKLCNLVMRLFKLXDMSGGILNFLPFLXHF 717
D ++L + F +G +++ +P+L +F
Sbjct: 216 HDDPEFRELLS-HNEEFGRTVGAGSLVDVMPWLQYF 250
>AY393998-1|AAQ87875.1| 543|Homo sapiens cytochrome P450, family 1,
subfamily B, polypeptide 1 protein.
Length = 543
Score = 50.4 bits (115), Expect = 7e-06
Identities = 48/216 (22%), Positives = 94/216 (43%), Gaps = 8/216 (3%)
Frame = +1
Query: 94 RRHRGLCYPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 273
RR + PPGP P++GN +V + HL + +++YG++ +RLGS +VV
Sbjct: 43 RRRQLRSAPPGPFAWPLIGNAAAV------GQAAHLSFARLARRYGDVFQIRLGSCPIVV 96
Query: 274 VTGIELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNF 447
+ G I + V F RP + + S G+ + W RR ++NF
Sbjct: 97 LNGERAIHQALVQQGSAFADRPAFASFRVVSGGRSMAFGHY-SEHWKVQRRAAHSMMRNF 155
Query: 448 ----GYNSRFMNVYIGEECEALVQLRFADAGEPILVN--QMFHITIVNILWRLVAGKRYD 609
+ + + ++ E LV L + + ++ + + + N++ + G RY
Sbjct: 156 FTRQPRSRQVLEGHVLSEARELVALLVRGSADGAFLDPRPLTVVAVANVMSAVCFGCRYS 215
Query: 610 LXDQRLKKLCNLVMRLFKLXDMSGGILNFLPFLXHF 717
D ++L + F +G +++ +P+L +F
Sbjct: 216 HDDPEFRELLS-HNEEFGRTVGAGSLVDVMPWLQYF 250
>AF450132-1|AAM50512.1| 543|Homo sapiens cytochrome P450 CYP1B1
protein.
Length = 543
Score = 50.4 bits (115), Expect = 7e-06
Identities = 48/216 (22%), Positives = 94/216 (43%), Gaps = 8/216 (3%)
Frame = +1
Query: 94 RRHRGLCYPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 273
RR + PPGP P++GN +V + HL + +++YG++ +RLGS +VV
Sbjct: 43 RRRQLRSAPPGPFAWPLIGNAAAV------GQAAHLSFARLARRYGDVFQIRLGSCPIVV 96
Query: 274 VTGIELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNF 447
+ G I + V F RP + + S G+ + W RR ++NF
Sbjct: 97 LNGERAIHQALVQQGSAFADRPAFASFRVVSGGRSMAFGHY-SEHWKVQRRAAHSMMRNF 155
Query: 448 ----GYNSRFMNVYIGEECEALVQLRFADAGEPILVN--QMFHITIVNILWRLVAGKRYD 609
+ + + ++ E LV L + + ++ + + + N++ + G RY
Sbjct: 156 FTRQPRSRQVLEGHVLSEARELVALLVRGSADGAFLDPRPLTVVAVANVMSAVCFGCRYS 215
Query: 610 LXDQRLKKLCNLVMRLFKLXDMSGGILNFLPFLXHF 717
D ++L + F +G +++ +P+L +F
Sbjct: 216 HDDPEFRELLS-HNEEFGRTVGAGSLVDVMPWLQYF 250
>AC009229-2|AAY15039.1| 543|Homo sapiens unknown protein.
Length = 543
Score = 50.4 bits (115), Expect = 7e-06
Identities = 48/216 (22%), Positives = 94/216 (43%), Gaps = 8/216 (3%)
Frame = +1
Query: 94 RRHRGLCYPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 273
RR + PPGP P++GN +V + HL + +++YG++ +RLGS +VV
Sbjct: 43 RRRQLRSAPPGPFAWPLIGNAAAV------GQAAHLSFARLARRYGDVFQIRLGSCPIVV 96
Query: 274 VTGIELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNF 447
+ G I + V F RP + + S G+ + W RR ++NF
Sbjct: 97 LNGERAIHQALVQQGSAFADRPAFASFRVVSGGRSMAFGHY-SEHWKVQRRAAHSMMRNF 155
Query: 448 ----GYNSRFMNVYIGEECEALVQLRFADAGEPILVN--QMFHITIVNILWRLVAGKRYD 609
+ + + ++ E LV L + + ++ + + + N++ + G RY
Sbjct: 156 FTRQPRSRQVLEGHVLSEARELVALLVRGSADGAFLDPRPLTVVAVANVMSAVCFGCRYS 215
Query: 610 LXDQRLKKLCNLVMRLFKLXDMSGGILNFLPFLXHF 717
D ++L + F +G +++ +P+L +F
Sbjct: 216 HDDPEFRELLS-HNEEFGRTVGAGSLVDVMPWLQYF 250
>BT020001-1|AAV38804.1| 543|Homo sapiens cytochrome P450, family 1,
subfamily B, polypeptide 1 protein.
Length = 543
Score = 49.6 bits (113), Expect = 1e-05
Identities = 48/216 (22%), Positives = 94/216 (43%), Gaps = 8/216 (3%)
Frame = +1
Query: 94 RRHRGLCYPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 273
RR + PPGP P++GN +V + HL + +++YG++ +RLGS +VV
Sbjct: 43 RRRQLRSAPPGPFAWPLIGNAAAV------GQAAHLSFARLARRYGDVFQIRLGSCPIVV 96
Query: 274 VTGIELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNF 447
+ G I + V F RP + + S G+ + W RR ++NF
Sbjct: 97 LNGERAIHQALVQQGSAFADRPAFASFRVVSGGRSMAFGHY-SEHWKVQRRAAHSMMRNF 155
Query: 448 ----GYNSRFMNVYIGEECEALVQLRFADAGEPILVN--QMFHITIVNILWRLVAGKRYD 609
+ + + ++ E LV L + + ++ + + + N++ + G RY
Sbjct: 156 FTRQPRSRQVLEGHVLSEARELVALLVRGSADGAFLDPRPLTVVAMANVMSAVCFGCRYS 215
Query: 610 LXDQRLKKLCNLVMRLFKLXDMSGGILNFLPFLXHF 717
D ++L + F +G +++ +P+L +F
Sbjct: 216 HDDPEFRELLS-HNEEFGRTVGAGSLVDVMPWLQYF 250
>BC109084-1|AAI09085.1| 448|Homo sapiens CYP24A1 protein protein.
Length = 448
Score = 46.0 bits (104), Expect = 2e-04
Identities = 33/115 (28%), Positives = 54/115 (46%), Gaps = 5/115 (4%)
Frame = +1
Query: 121 PGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIKE 300
PGPT P++G+L+ +LW+ K H + + + +KYG + ++LGS V + L++
Sbjct: 59 PGPTSWPLLGSLLQILWKGGLKKQHDTLVE-YHKKYGKIFRMKLGSFESVHLGSPCLLEA 117
Query: 301 VSNREV-----FEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFG 450
+ E E +P + R G GL+ +G W R R K L G
Sbjct: 118 LYRTESAYPQRLEIKPWKAYRDYRKEG--YGLLILEGEDWQRVRSAFQKKLMKPG 170
>BC109083-1|AAI09084.1| 448|Homo sapiens CYP24A1 protein protein.
Length = 448
Score = 46.0 bits (104), Expect = 2e-04
Identities = 33/115 (28%), Positives = 54/115 (46%), Gaps = 5/115 (4%)
Frame = +1
Query: 121 PGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIKE 300
PGPT P++G+L+ +LW+ K H + + + +KYG + ++LGS V + L++
Sbjct: 59 PGPTSWPLLGSLLQILWKGGLKKQHDTLVE-YHKKYGKIFRMKLGSFESVHLGSPCLLEA 117
Query: 301 VSNREV-----FEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFG 450
+ E E +P + R G GL+ +G W R R K L G
Sbjct: 118 LYRTESAYPQRLEIKPWKAYRDYRKEG--YGLLILEGEDWQRVRSAFQKKLMKPG 170
>AL138805-3|CAM27343.1| 448|Homo sapiens cytochrome P450, family
24, subfamily A, polypeptide 1 protein.
Length = 448
Score = 46.0 bits (104), Expect = 2e-04
Identities = 33/115 (28%), Positives = 54/115 (46%), Gaps = 5/115 (4%)
Frame = +1
Query: 121 PGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIKE 300
PGPT P++G+L+ +LW+ K H + + + +KYG + ++LGS V + L++
Sbjct: 59 PGPTSWPLLGSLLQILWKGGLKKQHDTLVE-YHKKYGKIFRMKLGSFESVHLGSPCLLEA 117
Query: 301 VSNREV-----FEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFG 450
+ E E +P + R G GL+ +G W R R K L G
Sbjct: 118 LYRTESAYPQRLEIKPWKAYRDYRKEG--YGLLILEGEDWQRVRSAFQKKLMKPG 170
>AL138805-2|CAB91829.1| 514|Homo sapiens cytochrome P450, family
24, subfamily A, polypeptide 1 protein.
Length = 514
Score = 46.0 bits (104), Expect = 2e-04
Identities = 33/115 (28%), Positives = 54/115 (46%), Gaps = 5/115 (4%)
Frame = +1
Query: 121 PGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIKE 300
PGPT P++G+L+ +LW+ K H + + + +KYG + ++LGS V + L++
Sbjct: 59 PGPTSWPLLGSLLQILWKGGLKKQHDTLVE-YHKKYGKIFRMKLGSFESVHLGSPCLLEA 117
Query: 301 VSNREV-----FEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTRRFVLKYLKNFG 450
+ E E +P + R G GL+ +G W R R K L G
Sbjct: 118 LYRTESAYPQRLEIKPWKAYRDYRKEG--YGLLILEGEDWQRVRSAFQKKLMKPG 170
>L13286-1|AAA62379.1| 513|Homo sapiens 1,25-dihydroxyvitamin D3
24-hydroxylase protein.
Length = 513
Score = 45.6 bits (103), Expect = 2e-04
Identities = 31/112 (27%), Positives = 54/112 (48%), Gaps = 2/112 (1%)
Frame = +1
Query: 121 PGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIKE 300
PGPT P++ +L+ +LW+ K H + + + +KYG + ++LGS V + L++
Sbjct: 59 PGPTSWPLLASLLQILWKGGLKKQHDTLVE-YHKKYGKIFRMKLGSFESVHLGSPCLLEA 117
Query: 301 VSNREVFEGRPD-GFFYTMRSFGKK-LGLVFSDGPTWHRTRRFVLKYLKNFG 450
+ E R + + R + K+ GL+ +G W R R K L G
Sbjct: 118 LYRTESVPQRLEIKPWKAYRDYRKEGYGLLILEGEDWQRVRSAFQKKLMKPG 169
>AY513607-1|AAR90938.1| 100|Homo sapiens truncated cytochrome P450
2A13 variant 4 protein.
Length = 100
Score = 45.2 bits (102), Expect = 3e-04
Identities = 29/80 (36%), Positives = 41/80 (51%), Gaps = 2/80 (2%)
Frame = +1
Query: 94 RRHRGLCYPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 273
R+ RG PPGPTPLP +GN + + E + S++YG + + LG VVV
Sbjct: 27 RKSRGKL-PPGPTPLPFIGNYLQLNTEQMYNSLMKI-----SERYGPVFTIHLGPRRVVV 80
Query: 274 VTGIELIKE--VSNREVFEG 327
+ G + +KE V E F G
Sbjct: 81 LCGHDAVKEALVDQAEEFSG 100
>CR456430-1|CAG30316.1| 446|Homo sapiens CYP2D6 protein.
Length = 446
Score = 44.8 bits (101), Expect = 4e-04
Identities = 30/99 (30%), Positives = 53/99 (53%), Gaps = 3/99 (3%)
Frame = +1
Query: 85 IISRRHRGLC-YPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSI 261
++ RR R YPPGP PLP +GNL+ V +++ + C + +++G++ L+L
Sbjct: 22 LMHRRQRWAARYPPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWT 76
Query: 262 NVVVVTGIELIKE--VSNREVFEGRPDGFFYTMRSFGKK 372
VVV+ G+ ++E V++ E RP + FG +
Sbjct: 77 PVVVLNGLAAVREALVTHGEDTADRPPVPITQILGFGPR 115
Score = 34.3 bits (75), Expect = 0.51
Identities = 21/71 (29%), Positives = 33/71 (46%), Gaps = 1/71 (1%)
Frame = +1
Query: 526 GEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCNLVMR-LFKLXDMSGGILNFLP 702
G P N + + N++ L G+R++ D R +L +L L + +LN +P
Sbjct: 118 GRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVP 177
Query: 703 FLXHFIPRLIG 735
L H IP L G
Sbjct: 178 VLLH-IPALAG 187
>BC106757-1|AAI06758.1| 446|Homo sapiens cytochrome P450, family 2,
subfamily D, polypeptide 6 protein.
Length = 446
Score = 44.8 bits (101), Expect = 4e-04
Identities = 30/99 (30%), Positives = 53/99 (53%), Gaps = 3/99 (3%)
Frame = +1
Query: 85 IISRRHRGLC-YPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSI 261
++ RR R YPPGP PLP +GNL+ V +++ + C + +++G++ L+L
Sbjct: 22 LMHRRQRWAARYPPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWT 76
Query: 262 NVVVVTGIELIKE--VSNREVFEGRPDGFFYTMRSFGKK 372
VVV+ G+ ++E V++ E RP + FG +
Sbjct: 77 PVVVLNGLAAVREALVTHGEDTADRPPVPITQILGFGPR 115
Score = 34.3 bits (75), Expect = 0.51
Identities = 21/71 (29%), Positives = 33/71 (46%), Gaps = 1/71 (1%)
Frame = +1
Query: 526 GEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCNLVMR-LFKLXDMSGGILNFLP 702
G P N + + N++ L G+R++ D R +L +L L + +LN +P
Sbjct: 118 GRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVP 177
Query: 703 FLXHFIPRLIG 735
L H IP L G
Sbjct: 178 VLLH-IPALAG 187
>BC066877-1|AAH66877.1| 446|Homo sapiens CYP2D6 protein protein.
Length = 446
Score = 44.8 bits (101), Expect = 4e-04
Identities = 30/99 (30%), Positives = 53/99 (53%), Gaps = 3/99 (3%)
Frame = +1
Query: 85 IISRRHRGLC-YPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSI 261
++ RR R YPPGP PLP +GNL+ V +++ + C + +++G++ L+L
Sbjct: 22 LMHRRQRWAARYPPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWT 76
Query: 262 NVVVVTGIELIKE--VSNREVFEGRPDGFFYTMRSFGKK 372
VVV+ G+ ++E V++ E RP + FG +
Sbjct: 77 PVVVLNGLAAVREALVTHGEDTADRPPVPITQILGFGPR 115
Score = 34.3 bits (75), Expect = 0.51
Identities = 21/71 (29%), Positives = 33/71 (46%), Gaps = 1/71 (1%)
Frame = +1
Query: 526 GEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCNLVMR-LFKLXDMSGGILNFLP 702
G P N + + N++ L G+R++ D R +L +L L + +LN +P
Sbjct: 118 GRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVP 177
Query: 703 FLXHFIPRLIG 735
L H IP L G
Sbjct: 178 VLLH-IPALAG 187
>J04813-1|AAA02993.1| 502|Homo sapiens cytochrome P450 PCN3
protein.
Length = 502
Score = 42.3 bits (95), Expect = 0.002
Identities = 40/153 (26%), Positives = 69/153 (45%), Gaps = 8/153 (5%)
Frame = +1
Query: 121 PGPTPLPVVGNLISVLWESRKF--KCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELI 294
PGPTPLP++GN++S KF +C+ +KYG + G G + V+ +T ++I
Sbjct: 39 PGPTPLPLLGNVLSYRQGLWKFDTECY--------KKYGKMWGTYEGQLPVLAITDPDVI 90
Query: 295 KEVSNREVFEGRPDGFFYTMRSFG----KKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSR 462
+ V +E + F RS G K + ++ W R R + +
Sbjct: 91 RTVLVKECY-----SVFTNRRSLGPVGFMKSAISLAEDEEWKRIRSLLSPTFTSGKLKEM 145
Query: 463 FMNVYIGEECEALVQ--LRFADAGEPILVNQMF 555
F I + + LV+ R A+ G+P+ + +F
Sbjct: 146 F--PIIAQYGDVLVRNLRREAEKGKPVTLKDIF 176
>DQ680079-1|ABG25922.1| 347|Homo sapiens truncated cytochrome P450,
family 3, subfamily A, polypeptide 5 protein.
Length = 347
Score = 42.3 bits (95), Expect = 0.002
Identities = 40/153 (26%), Positives = 69/153 (45%), Gaps = 8/153 (5%)
Frame = +1
Query: 121 PGPTPLPVVGNLISVLWESRKF--KCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELI 294
PGPTPLP++GN++S KF +C+ +KYG + G G + V+ +T ++I
Sbjct: 39 PGPTPLPLLGNVLSYRQGLWKFDTECY--------KKYGKMWGTYEGQLPVLAITDPDVI 90
Query: 295 KEVSNREVFEGRPDGFFYTMRSFG----KKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSR 462
+ V +E + F RS G K + ++ W R R + +
Sbjct: 91 RTVLVKECY-----SVFTNRRSLGPVGFMKSAISLAEDEEWKRIRSLLSPTFTSGKLKEM 145
Query: 463 FMNVYIGEECEALVQ--LRFADAGEPILVNQMF 555
F I + + LV+ R A+ G+P+ + +F
Sbjct: 146 F--PIIAQYGDVLVRNLRREAEKGKPVTLKDIF 176
>BC033862-1|AAH33862.1| 502|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 5 protein.
Length = 502
Score = 42.3 bits (95), Expect = 0.002
Identities = 40/153 (26%), Positives = 69/153 (45%), Gaps = 8/153 (5%)
Frame = +1
Query: 121 PGPTPLPVVGNLISVLWESRKF--KCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELI 294
PGPTPLP++GN++S KF +C+ +KYG + G G + V+ +T ++I
Sbjct: 39 PGPTPLPLLGNVLSYRQGLWKFDTECY--------KKYGKMWGTYEGQLPVLAITDPDVI 90
Query: 295 KEVSNREVFEGRPDGFFYTMRSFG----KKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSR 462
+ V +E + F RS G K + ++ W R R + +
Sbjct: 91 RTVLVKECY-----SVFTNRRSLGPVGFMKSAISLAEDEEWKRIRSLLSPTFTSGKLKEM 145
Query: 463 FMNVYIGEECEALVQ--LRFADAGEPILVNQMF 555
F I + + LV+ R A+ G+P+ + +F
Sbjct: 146 F--PIIAQYGDVLVRNLRREAEKGKPVTLKDIF 176
>AC005020-1|AAS02016.1| 502|Homo sapiens unknown protein.
Length = 502
Score = 42.3 bits (95), Expect = 0.002
Identities = 40/153 (26%), Positives = 69/153 (45%), Gaps = 8/153 (5%)
Frame = +1
Query: 121 PGPTPLPVVGNLISVLWESRKF--KCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELI 294
PGPTPLP++GN++S KF +C+ +KYG + G G + V+ +T ++I
Sbjct: 39 PGPTPLPLLGNVLSYRQGLWKFDTECY--------KKYGKMWGTYEGQLPVLAITDPDVI 90
Query: 295 KEVSNREVFEGRPDGFFYTMRSFG----KKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSR 462
+ V +E + F RS G K + ++ W R R + +
Sbjct: 91 RTVLVKECY-----SVFTNRRSLGPVGFMKSAISLAEDEEWKRIRSLLSPTFTSGKLKEM 145
Query: 463 FMNVYIGEECEALVQ--LRFADAGEPILVNQMF 555
F I + + LV+ R A+ G+P+ + +F
Sbjct: 146 F--PIIAQYGDVLVRNLRREAEKGKPVTLKDIF 176
>J04449-1|AAA35747.1| 502|Homo sapiens cytochrome P450 nifedipine
oxidase protein.
Length = 502
Score = 41.9 bits (94), Expect = 0.003
Identities = 48/203 (23%), Positives = 84/203 (41%), Gaps = 7/203 (3%)
Frame = +1
Query: 121 PGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIKE 300
PGPTPLP +GN++S K C + +KYG + G G V+ +T ++IK
Sbjct: 39 PGPTPLPFLGNILSY----HKGFC--MFDMECHKKYGKVCGFYDGQQPVLAITDPDMIKT 92
Query: 301 VSNREVFEGRPDGFFYTMRSFG----KKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFM 468
V +E + F R FG K + ++ W R R +L G +
Sbjct: 93 VLVKECY-----SVFTNRRPFGPVGFMKSAISIAEDEEWKRLRS-LLSPTFTSGKLKEMV 146
Query: 469 NVYIGEECEALVQ--LRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCN 642
+ I + + LV+ R A+ G+P+ + +F ++++ G D +
Sbjct: 147 PI-IAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNIDSLNNPQDPFVE 205
Query: 643 LVMRLFKLXDMSGGILNFL-PFL 708
+L + + L+ + PFL
Sbjct: 206 NTKKLLRFDFLDPFFLSIIFPFL 228
>AK223008-1|BAD96728.1| 502|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 5 variant protein.
Length = 502
Score = 41.9 bits (94), Expect = 0.003
Identities = 40/153 (26%), Positives = 69/153 (45%), Gaps = 8/153 (5%)
Frame = +1
Query: 121 PGPTPLPVVGNLISVLWESRKF--KCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELI 294
PGPTPLP++GN++S KF +C+ +KYG + G G + V+ +T ++I
Sbjct: 39 PGPTPLPLLGNVLSYRQGLWKFDTECY--------KKYGKMWGTYEGQLPVLAITDPDVI 90
Query: 295 KEVSNREVFEGRPDGFFYTMRSFG----KKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSR 462
+ V +E + F RS G K + ++ W R R + +
Sbjct: 91 RTVLVKECY-----SVFTNRRSLGPVGFMKSAISLAEDEEWKRIRPLLSPTFTSGKLKEM 145
Query: 463 FMNVYIGEECEALVQ--LRFADAGEPILVNQMF 555
F I + + LV+ R A+ G+P+ + +F
Sbjct: 146 F--PIIAQYGDVLVRNLRREAEKGKPVTLKDIF 176
>DQ211355-2|ABB01373.1| 117|Homo sapiens cytochrome P450 2D6
protein.
Length = 117
Score = 41.5 bits (93), Expect = 0.003
Identities = 29/99 (29%), Positives = 52/99 (52%), Gaps = 3/99 (3%)
Frame = +1
Query: 85 IISRRHRGLC-YPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSI 261
++ RR R Y PGP PLP +GNL+ V +++ + C + +++G++ L+L
Sbjct: 22 LMHRRQRWAARYSPGPLPLPGLGNLLHVDFQNTPY-C----FDQLRRRFGDVFSLQLAWT 76
Query: 262 NVVVVTGIELIKE--VSNREVFEGRPDGFFYTMRSFGKK 372
VVV+ G+ ++E V++ E RP + FG +
Sbjct: 77 PVVVLNGLAAVREALVTHGEDTADRPPVPITQILGFGPR 115
>X12387-1|CAA30944.1| 503|Homo sapiens protein ( Human mRNA for
cytochrome P-450 (cyp3 locus). ).
Length = 503
Score = 41.1 bits (92), Expect = 0.004
Identities = 43/169 (25%), Positives = 73/169 (43%), Gaps = 6/169 (3%)
Frame = +1
Query: 121 PGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIKE 300
PGPTPLP +GN++S K C + +KYG + G G V+ +T ++IK
Sbjct: 39 PGPTPLPFLGNILSY----HKGFC--MFDMECHKKYGKVWGFYDGQQPVLAITDPDMIKT 92
Query: 301 VSNREVFEGRPDGFFYTMRSFG----KKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFM 468
V +E + F R FG K + ++ W R R +L G +
Sbjct: 93 VLVKECY-----SVFTNRRPFGPVGFMKSAISIAEDEEWKRLRS-LLSPTFTSGKLKEMV 146
Query: 469 NVYIGEECEALVQ--LRFADAGEPILVNQMFHITIVNILWRLVAGKRYD 609
+ I + + LV+ R A+ G+P+ + +F ++++ G D
Sbjct: 147 PI-IAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNID 194
>M18907-1|AAA35745.1| 503|Homo sapiens protein ( Human P450 mRNA
encoding nifedipine oxidase, complete cds. ).
Length = 503
Score = 41.1 bits (92), Expect = 0.004
Identities = 43/169 (25%), Positives = 73/169 (43%), Gaps = 6/169 (3%)
Frame = +1
Query: 121 PGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIKE 300
PGPTPLP +GN++S K C + +KYG + G G V+ +T ++IK
Sbjct: 39 PGPTPLPFLGNILSY----HKGFC--MFDMECHKKYGKVWGFYDGQQPVLAITDPDMIKT 92
Query: 301 VSNREVFEGRPDGFFYTMRSFG----KKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFM 468
V +E + F R FG K + ++ W R R +L G +
Sbjct: 93 VLVKECY-----SVFTNRRPFGPVGFMKSAISIAEDEEWKRLRS-LLSPTFTSGKLKEMV 146
Query: 469 NVYIGEECEALVQ--LRFADAGEPILVNQMFHITIVNILWRLVAGKRYD 609
+ I + + LV+ R A+ G+P+ + +F ++++ G D
Sbjct: 147 PI-IAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNID 194
>M14096-1|AAA35744.1| 503|Homo sapiens protein ( Human cytochrome
P-450 nifedipine oxidase mRNA, complet cds. ).
Length = 503
Score = 41.1 bits (92), Expect = 0.004
Identities = 43/169 (25%), Positives = 73/169 (43%), Gaps = 6/169 (3%)
Frame = +1
Query: 121 PGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIKE 300
PGPTPLP +GN++S K C + +KYG + G G V+ +T ++IK
Sbjct: 39 PGPTPLPFLGNILSY----HKGFC--MFDMECHKKYGKVWGFYDGQQPVLAITDPDMIKT 92
Query: 301 VSNREVFEGRPDGFFYTMRSFG----KKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFM 468
V +E + F R FG K + ++ W R R +L G +
Sbjct: 93 VLVKECY-----SVFTNRRPFGPVGFMKSAISIAEDEEWKRLRS-LLSPTFTSGKLKEMV 146
Query: 469 NVYIGEECEALVQ--LRFADAGEPILVNQMFHITIVNILWRLVAGKRYD 609
+ I + + LV+ R A+ G+P+ + +F ++++ G D
Sbjct: 147 PI-IAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNID 194
>DQ924960-1|ABI96208.1| 503|Homo sapiens cytochrome P450 family 3
subfamily A polypeptide 4 protein.
Length = 503
Score = 41.1 bits (92), Expect = 0.004
Identities = 43/169 (25%), Positives = 73/169 (43%), Gaps = 6/169 (3%)
Frame = +1
Query: 121 PGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIKE 300
PGPTPLP +GN++S K C + +KYG + G G V+ +T ++IK
Sbjct: 39 PGPTPLPFLGNILSY----HKGFC--MFDMECHKKYGKVWGFYDGQQPVLAITDPDMIKT 92
Query: 301 VSNREVFEGRPDGFFYTMRSFG----KKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFM 468
V +E + F R FG K + ++ W R R +L G +
Sbjct: 93 VLVKECY-----SVFTNRRPFGPVGFMKSAISIAEDEEWKRLRS-LLSPTFTSGKLKEMV 146
Query: 469 NVYIGEECEALVQ--LRFADAGEPILVNQMFHITIVNILWRLVAGKRYD 609
+ I + + LV+ R A+ G+P+ + +F ++++ G D
Sbjct: 147 PI-IAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNID 194
>DQ005611-1|AAY16980.1| 503|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 4 protein.
Length = 503
Score = 41.1 bits (92), Expect = 0.004
Identities = 43/169 (25%), Positives = 73/169 (43%), Gaps = 6/169 (3%)
Frame = +1
Query: 121 PGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIKE 300
PGPTPLP +GN++S K C + +KYG + G G V+ +T ++IK
Sbjct: 39 PGPTPLPFLGNILSY----HKGFC--MFDMECHKKYGKVWGFYDGQQPVLAITDPDMIKT 92
Query: 301 VSNREVFEGRPDGFFYTMRSFG----KKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFM 468
V +E + F R FG K + ++ W R R +L G +
Sbjct: 93 VLVKECY-----SVFTNRRPFGPVGFMKSAISIAEDEEWKRLRS-LLSPTFTSGKLKEMV 146
Query: 469 NVYIGEECEALVQ--LRFADAGEPILVNQMFHITIVNILWRLVAGKRYD 609
+ I + + LV+ R A+ G+P+ + +F ++++ G D
Sbjct: 147 PI-IAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNID 194
>BC101631-1|AAI01632.1| 503|Homo sapiens cytochrome P450, subfamily
IIIA, polypeptide 4 protein.
Length = 503
Score = 41.1 bits (92), Expect = 0.004
Identities = 43/169 (25%), Positives = 73/169 (43%), Gaps = 6/169 (3%)
Frame = +1
Query: 121 PGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIKE 300
PGPTPLP +GN++S K C + +KYG + G G V+ +T ++IK
Sbjct: 39 PGPTPLPFLGNILSY----HKGFC--MFDMECHKKYGKVWGFYDGQQPVLAITDPDMIKT 92
Query: 301 VSNREVFEGRPDGFFYTMRSFG----KKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFM 468
V +E + F R FG K + ++ W R R +L G +
Sbjct: 93 VLVKECY-----SVFTNRRPFGPVGFMKSAISIAEDEEWKRLRS-LLSPTFTSGKLKEMV 146
Query: 469 NVYIGEECEALVQ--LRFADAGEPILVNQMFHITIVNILWRLVAGKRYD 609
+ I + + LV+ R A+ G+P+ + +F ++++ G D
Sbjct: 147 PI-IAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNID 194
>BC069418-1|AAH69418.1| 503|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 4 protein.
Length = 503
Score = 41.1 bits (92), Expect = 0.004
Identities = 43/169 (25%), Positives = 73/169 (43%), Gaps = 6/169 (3%)
Frame = +1
Query: 121 PGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIKE 300
PGPTPLP +GN++S K C + +KYG + G G V+ +T ++IK
Sbjct: 39 PGPTPLPFLGNILSY----HKGFC--MFDMECHKKYGKVWGFYDGQQPVLAITDPDMIKT 92
Query: 301 VSNREVFEGRPDGFFYTMRSFG----KKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFM 468
V +E + F R FG K + ++ W R R +L G +
Sbjct: 93 VLVKECY-----SVFTNRRPFGPVGFMKSAISIAEDEEWKRLRS-LLSPTFTSGKLKEMV 146
Query: 469 NVYIGEECEALVQ--LRFADAGEPILVNQMFHITIVNILWRLVAGKRYD 609
+ I + + LV+ R A+ G+P+ + +F ++++ G D
Sbjct: 147 PI-IAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNID 194
>AJ563375-1|CAD91343.1| 503|Homo sapiens cytochrome P450 protein.
Length = 503
Score = 41.1 bits (92), Expect = 0.004
Identities = 43/169 (25%), Positives = 73/169 (43%), Gaps = 6/169 (3%)
Frame = +1
Query: 121 PGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIKE 300
PGPTPLP +GN++S K C + +KYG + G G V+ +T ++IK
Sbjct: 39 PGPTPLPFLGNILSY----HKGFC--MFDMECHKKYGKVWGFYDGQQPVLAITDPDMIKT 92
Query: 301 VSNREVFEGRPDGFFYTMRSFG----KKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFM 468
V +E + F R FG K + ++ W R R +L G +
Sbjct: 93 VLVKECY-----SVFTNRRPFGPVGFMKSAISIAEDEEWKRLRS-LLSPTFTSGKLKEMV 146
Query: 469 NVYIGEECEALVQ--LRFADAGEPILVNQMFHITIVNILWRLVAGKRYD 609
+ I + + LV+ R A+ G+P+ + +F ++++ G D
Sbjct: 147 PI-IAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNID 194
>AF280107-2|AAG32290.1| 503|Homo sapiens cytochrome P450
polypeptide 4 protein.
Length = 503
Score = 41.1 bits (92), Expect = 0.004
Identities = 43/169 (25%), Positives = 73/169 (43%), Gaps = 6/169 (3%)
Frame = +1
Query: 121 PGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIKE 300
PGPTPLP +GN++S K C + +KYG + G G V+ +T ++IK
Sbjct: 39 PGPTPLPFLGNILSY----HKGFC--MFDMECHKKYGKVWGFYDGQQPVLAITDPDMIKT 92
Query: 301 VSNREVFEGRPDGFFYTMRSFG----KKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFM 468
V +E + F R FG K + ++ W R R +L G +
Sbjct: 93 VLVKECY-----SVFTNRRPFGPVGFMKSAISIAEDEEWKRLRS-LLSPTFTSGKLKEMV 146
Query: 469 NVYIGEECEALVQ--LRFADAGEPILVNQMFHITIVNILWRLVAGKRYD 609
+ I + + LV+ R A+ G+P+ + +F ++++ G D
Sbjct: 147 PI-IAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNID 194
>AF209389-1|AAF21034.1| 503|Homo sapiens cytochrome P450 IIIA4
protein.
Length = 503
Score = 41.1 bits (92), Expect = 0.004
Identities = 43/169 (25%), Positives = 73/169 (43%), Gaps = 6/169 (3%)
Frame = +1
Query: 121 PGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIKE 300
PGPTPLP +GN++S K C + +KYG + G G V+ +T ++IK
Sbjct: 39 PGPTPLPFLGNILSY----HKGFC--MFDMECHKKYGKVWGFYDGQQPVLAITDPDMIKT 92
Query: 301 VSNREVFEGRPDGFFYTMRSFG----KKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFM 468
V +E + F R FG K + ++ W R R +L G +
Sbjct: 93 VLVKECY-----SVFTNRRPFGPVGFMKSAISIAEDEEWKRLRS-LLSPTFTSGKLKEMV 146
Query: 469 NVYIGEECEALVQ--LRFADAGEPILVNQMFHITIVNILWRLVAGKRYD 609
+ I + + LV+ R A+ G+P+ + +F ++++ G D
Sbjct: 147 PI-IAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNID 194
>AF182273-1|AAF13598.1| 503|Homo sapiens cytochrome P450-3A4
protein.
Length = 503
Score = 41.1 bits (92), Expect = 0.004
Identities = 43/169 (25%), Positives = 73/169 (43%), Gaps = 6/169 (3%)
Frame = +1
Query: 121 PGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIKE 300
PGPTPLP +GN++S K C + +KYG + G G V+ +T ++IK
Sbjct: 39 PGPTPLPFLGNILSY----HKGFC--MFDMECHKKYGKVWGFYDGQQPVLAITDPDMIKT 92
Query: 301 VSNREVFEGRPDGFFYTMRSFG----KKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFM 468
V +E + F R FG K + ++ W R R +L G +
Sbjct: 93 VLVKECY-----SVFTNRRPFGPVGFMKSAISIAEDEEWKRLRS-LLSPTFTSGKLKEMV 146
Query: 469 NVYIGEECEALVQ--LRFADAGEPILVNQMFHITIVNILWRLVAGKRYD 609
+ I + + LV+ R A+ G+P+ + +F ++++ G D
Sbjct: 147 PI-IAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNID 194
>DQ372705-1|ABD16216.1| 150|Homo sapiens mutant cytochrome p450
protein.
Length = 150
Score = 40.7 bits (91), Expect = 0.006
Identities = 26/82 (31%), Positives = 41/82 (50%), Gaps = 2/82 (2%)
Frame = +1
Query: 94 RRHRGLCYPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVV 273
RR + PPGP P++GN +V + HL + +++YG++ +RLGS +VV
Sbjct: 43 RRRQLRSAPPGPFAWPLIGNAAAV------GQAAHLSFARLARRYGDVFQIRLGSCPIVV 96
Query: 274 VTGIELIKE--VSNREVFEGRP 333
+ G I + V F RP
Sbjct: 97 LNGERAIHQALVQQGSAFADRP 118
>AF280107-4|AAG32288.1| 106|Homo sapiens cytochrome P450
polypeptide 5 protein.
Length = 106
Score = 39.1 bits (87), Expect = 0.018
Identities = 23/69 (33%), Positives = 39/69 (56%), Gaps = 2/69 (2%)
Frame = +1
Query: 121 PGPTPLPVVGNLISVLWESRKF--KCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELI 294
PGPTPLP++GN++S KF +C+ +KYG + G G + V+ +T ++I
Sbjct: 39 PGPTPLPLLGNVLSYRQGLWKFDTECY--------KKYGKMWGTYEGQLPVLAITDPDVI 90
Query: 295 KEVSNREVF 321
+ V +E +
Sbjct: 91 RTVLVKECY 99
>AF171066-1|AAG43404.1| 112|Homo sapiens CYP1B1 variant protein.
Length = 112
Score = 38.7 bits (86), Expect = 0.024
Identities = 23/73 (31%), Positives = 40/73 (54%), Gaps = 1/73 (1%)
Frame = +1
Query: 85 IISRRHRGL-CYPPGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSI 261
++ +R R L PPGP P++GN +V + HL + +++YG++ +RLGS
Sbjct: 39 LLRQRRRQLGSAPPGPFAWPLIGNAAAV------GQAAHLSFARLARRYGDVFQIRLGSC 92
Query: 262 NVVVVTGIELIKE 300
+VV+ G I +
Sbjct: 93 PIVVLNGERAIHQ 105
>AY390425-1|AAQ92353.1| 503|Homo sapiens cytochrome P450 CYP3A43.1
protein.
Length = 503
Score = 37.5 bits (83), Expect = 0.055
Identities = 28/99 (28%), Positives = 45/99 (45%)
Frame = +1
Query: 121 PGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIKE 300
PGPTPLP +G ++ L F + ++KYG + GL G ++V+ ++IK
Sbjct: 39 PGPTPLPFLGTILFYLRGLWNFD------RECNEKYGEMWGLYEGQQPMLVIMDPDMIKT 92
Query: 301 VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTR 417
V +E + + F K L F++ W R R
Sbjct: 93 VLVKECYSVFTNQMPLGPMGF-LKSALSFAEDEEWKRIR 130
>AY390424-1|AAQ92352.1| 503|Homo sapiens cytochrome P450 CYP3A43.3
protein.
Length = 503
Score = 37.5 bits (83), Expect = 0.055
Identities = 28/99 (28%), Positives = 45/99 (45%)
Frame = +1
Query: 121 PGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIKE 300
PGPTPLP +G ++ L F + ++KYG + GL G ++V+ ++IK
Sbjct: 39 PGPTPLPFLGTILFYLRGLWNFD------RECNEKYGEMWGLYEGQQPMLVIMDPDMIKT 92
Query: 301 VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTR 417
V +E + + F K L F++ W R R
Sbjct: 93 VLVKECYSVFTNQMPLGPMGF-LKSALSFAEDEEWKRIR 130
>AF337813-1|AAK38841.1| 503|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 503
Score = 37.5 bits (83), Expect = 0.055
Identities = 28/99 (28%), Positives = 45/99 (45%)
Frame = +1
Query: 121 PGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIKE 300
PGPTPLP +G ++ L F + ++KYG + GL G ++V+ ++IK
Sbjct: 39 PGPTPLPFLGTILFYLRGLWNFD------RECNEKYGEMWGLYEGQQPMLVIMDPDMIKT 92
Query: 301 VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTR 417
V +E + + F K L F++ W R R
Sbjct: 93 VLVKECYSVFTNQMPLGPMGF-LKSALSFAEDEEWKRIR 130
>AF319634-1|AAK00325.1| 503|Homo sapiens cytochrome P450 CYP3A43
protein.
Length = 503
Score = 37.5 bits (83), Expect = 0.055
Identities = 28/99 (28%), Positives = 45/99 (45%)
Frame = +1
Query: 121 PGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIKE 300
PGPTPLP +G ++ L F + ++KYG + GL G ++V+ ++IK
Sbjct: 39 PGPTPLPFLGTILFYLRGLWNFD------RECNEKYGEMWGLYEGQQPMLVIMDPDMIKT 92
Query: 301 VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTR 417
V +E + + F K L F++ W R R
Sbjct: 93 VLVKECYSVFTNQMPLGPMGF-LKSALSFAEDEEWKRIR 130
>AF280111-1|AAG33012.1| 250|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 250
Score = 37.5 bits (83), Expect = 0.055
Identities = 28/99 (28%), Positives = 45/99 (45%)
Frame = +1
Query: 121 PGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIKE 300
PGPTPLP +G ++ L F + ++KYG + GL G ++V+ ++IK
Sbjct: 39 PGPTPLPFLGTILFYLRGLWNFD------RECNEKYGEMWGLYEGQQPMLVIMDPDMIKT 92
Query: 301 VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTR 417
V +E + + F K L F++ W R R
Sbjct: 93 VLVKECYSVFTNQMPLGPMGF-LKSALSFAEDEEWKRIR 130
>AF280110-1|AAG33011.1| 420|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 420
Score = 37.5 bits (83), Expect = 0.055
Identities = 28/99 (28%), Positives = 45/99 (45%)
Frame = +1
Query: 121 PGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIKE 300
PGPTPLP +G ++ L F + ++KYG + GL G ++V+ ++IK
Sbjct: 39 PGPTPLPFLGTILFYLRGLWNFD------RECNEKYGEMWGLYEGQQPMLVIMDPDMIKT 92
Query: 301 VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTR 417
V +E + + F K L F++ W R R
Sbjct: 93 VLVKECYSVFTNQMPLGPMGF-LKSALSFAEDEEWKRIR 130
>AF280109-1|AAG33010.1| 504|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 504
Score = 37.5 bits (83), Expect = 0.055
Identities = 28/99 (28%), Positives = 45/99 (45%)
Frame = +1
Query: 121 PGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIKE 300
PGPTPLP +G ++ L F + ++KYG + GL G ++V+ ++IK
Sbjct: 39 PGPTPLPFLGTILFYLRGLWNFD------RECNEKYGEMWGLYEGQQPMLVIMDPDMIKT 92
Query: 301 VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTR 417
V +E + + F K L F++ W R R
Sbjct: 93 VLVKECYSVFTNQMPLGPMGF-LKSALSFAEDEEWKRIR 130
>AF280108-1|AAG33009.1| 503|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 503
Score = 37.5 bits (83), Expect = 0.055
Identities = 28/99 (28%), Positives = 45/99 (45%)
Frame = +1
Query: 121 PGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIKE 300
PGPTPLP +G ++ L F + ++KYG + GL G ++V+ ++IK
Sbjct: 39 PGPTPLPFLGTILFYLRGLWNFD------RECNEKYGEMWGLYEGQQPMLVIMDPDMIKT 92
Query: 301 VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTR 417
V +E + + F K L F++ W R R
Sbjct: 93 VLVKECYSVFTNQMPLGPMGF-LKSALSFAEDEEWKRIR 130
>AC011904-5|AAS07394.1| 504|Homo sapiens unknown protein.
Length = 504
Score = 37.5 bits (83), Expect = 0.055
Identities = 28/99 (28%), Positives = 45/99 (45%)
Frame = +1
Query: 121 PGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIKE 300
PGPTPLP +G ++ L F + ++KYG + GL G ++V+ ++IK
Sbjct: 39 PGPTPLPFLGTILFYLRGLWNFD------RECNEKYGEMWGLYEGQQPMLVIMDPDMIKT 92
Query: 301 VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTR 417
V +E + + F K L F++ W R R
Sbjct: 93 VLVKECYSVFTNQMPLGPMGF-LKSALSFAEDEEWKRIR 130
>AC011904-4|AAS07395.1| 503|Homo sapiens unknown protein.
Length = 503
Score = 37.5 bits (83), Expect = 0.055
Identities = 28/99 (28%), Positives = 45/99 (45%)
Frame = +1
Query: 121 PGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIKE 300
PGPTPLP +G ++ L F + ++KYG + GL G ++V+ ++IK
Sbjct: 39 PGPTPLPFLGTILFYLRGLWNFD------RECNEKYGEMWGLYEGQQPMLVIMDPDMIKT 92
Query: 301 VSNREVFEGRPDGFFYTMRSFGKKLGLVFSDGPTWHRTR 417
V +E + + F K L F++ W R R
Sbjct: 93 VLVKECYSVFTNQMPLGPMGF-LKSALSFAEDEEWKRIR 130
>BC022539-1|AAH22539.1| 500|Homo sapiens cytochrome P450, family
46, subfamily A, polypeptide 1 protein.
Length = 500
Score = 37.1 bits (82), Expect = 0.073
Identities = 48/204 (23%), Positives = 83/204 (40%), Gaps = 9/204 (4%)
Frame = +1
Query: 118 PPGPTPLPVVGNLISVLWESRKFKCHHL--IWQSWSQKYGNLLGLRLGSINVVVVTGIEL 291
P P P ++G+L W+ + L ++ W++KYG ++ + + V+VT E
Sbjct: 34 PGPPRPSFLLGHL-PCFWKKDEVGGRVLQDVFLDWAKKYGPVVRVNVFHKTSVIVTSPES 92
Query: 292 IKEVSNREVFEGRPDGFFYTMRSFGKKL---GLVFS-DGPTWHRTRRFVLKYLKNFGYNS 459
+K+ + + FG++L GLV + WH+ RR + S
Sbjct: 93 VKKFLMSTKYNKDSKMYRALQTVFGERLFGQGLVSECNYERWHKQRRVIDLAFSRSSLVS 152
Query: 460 RFMNVYIGEECEALVQL--RFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKK 633
M + E+ E LV++ AD P+ + M T ++IL + G + K
Sbjct: 153 -LMETF-NEKAEQLVEILEAKADGQTPVSMQDMLTYTAMDILAKAAFGMETSMLLGAQKP 210
Query: 634 LCNLVMRLFKLXDMSGGIL-NFLP 702
L V + + S L FLP
Sbjct: 211 LSQAVKLMLEGITASRNTLAKFLP 234
>AF094480-1|AAD41244.1| 500|Homo sapiens cholesterol 24-hydroxylase
protein.
Length = 500
Score = 37.1 bits (82), Expect = 0.073
Identities = 48/204 (23%), Positives = 83/204 (40%), Gaps = 9/204 (4%)
Frame = +1
Query: 118 PPGPTPLPVVGNLISVLWESRKFKCHHL--IWQSWSQKYGNLLGLRLGSINVVVVTGIEL 291
P P P ++G+L W+ + L ++ W++KYG ++ + + V+VT E
Sbjct: 34 PGPPRPSFLLGHL-PCFWKKDEVGGRVLQDVFLDWAKKYGPVVRVNVFHKTSVIVTSPES 92
Query: 292 IKEVSNREVFEGRPDGFFYTMRSFGKKL---GLVFS-DGPTWHRTRRFVLKYLKNFGYNS 459
+K+ + + FG++L GLV + WH+ RR + S
Sbjct: 93 VKKFLMSTKYNKDSKMYRALQTVFGERLFGQGLVSECNYERWHKQRRVIDLAFSRSSLVS 152
Query: 460 RFMNVYIGEECEALVQL--RFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKK 633
M + E+ E LV++ AD P+ + M T ++IL + G + K
Sbjct: 153 -LMETF-NEKAEQLVEILEAKADGQTPVSMQDMLTYTAMDILAKAAFGMETSMLLGAQKP 210
Query: 634 LCNLVMRLFKLXDMSGGIL-NFLP 702
L V + + S L FLP
Sbjct: 211 LSQAVKLMLEGITASRNTLAKFLP 234
>M13785-1|AAA35742.1| 504|Homo sapiens protein ( Human liver
glucocorticoid-inducible cytochrome P-450 (HLp) mRNA,
complete cds. ).
Length = 504
Score = 36.7 bits (81), Expect = 0.096
Identities = 23/67 (34%), Positives = 35/67 (52%)
Frame = +1
Query: 121 PGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIKE 300
PGPTPLP +GN++S K C + +KYG + G G V+ +T ++IK
Sbjct: 39 PGPTPLPFLGNILSY----HKGFC--MFDMECHKKYGKVWGFYDGQQPVLAITDPDMIKL 92
Query: 301 VSNREVF 321
V +E +
Sbjct: 93 VLVKECY 99
>D00003-1|BAA00001.1| 504|Homo sapiens cytochrome P-450 protein.
Length = 504
Score = 36.7 bits (81), Expect = 0.096
Identities = 23/67 (34%), Positives = 35/67 (52%)
Frame = +1
Query: 121 PGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIKE 300
PGPTPLP +GN++S K C + +KYG + G G V+ +T ++IK
Sbjct: 39 PGPTPLPFLGNILSY----HKGFC--MFDMECHKKYGKVWGFYDGQQPVLAITDPDMIKL 92
Query: 301 VSNREVF 321
V +E +
Sbjct: 93 VLVKECY 99
>BC012027-1|AAH12027.1| 168|Homo sapiens CYP2U1 protein protein.
Length = 168
Score = 36.3 bits (80), Expect = 0.13
Identities = 30/100 (30%), Positives = 44/100 (44%), Gaps = 20/100 (20%)
Frame = +1
Query: 94 RRHRGLCYPPGPTPLPVVGNLISVL---------WESRKFKC---------HHLIWQSWS 219
RR R PPGPTP P+VGN VL W S + + ++ +
Sbjct: 52 RRRRARGIPPGPTPWPLVGNFGHVLLPPFLRRRSWLSSRTRAAGIDPSVIGPQVLLAHLA 111
Query: 220 QKYGNLLGLRLGSINVVVVTGIELIKE--VSNREVFEGRP 333
+ YG++ +G VVV++ ++E V EVF RP
Sbjct: 112 RVYGSIFSFFIGHYLVVVLSDFHSVREALVQQAEVFSDRP 151
>AF280107-1|AAG32291.1| 106|Homo sapiens cytochrome P450
polypeptide 43 protein.
Length = 106
Score = 35.5 bits (78), Expect = 0.22
Identities = 21/67 (31%), Positives = 35/67 (52%)
Frame = +1
Query: 121 PGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIKE 300
PGPTPLP +G ++ L F + ++KYG + GL G ++V+ ++IK
Sbjct: 39 PGPTPLPFLGTILFYLRGLWNFD------RECNEKYGEMWGLYEGQQPMLVIMDPDMIKT 92
Query: 301 VSNREVF 321
V +E +
Sbjct: 93 VLVKECY 99
>M61858-1|AAA52145.1| 370|Homo sapiens CYP2C17 protein.
Length = 370
Score = 35.1 bits (77), Expect = 0.29
Identities = 24/75 (32%), Positives = 36/75 (48%), Gaps = 1/75 (1%)
Frame = +1
Query: 415 RRFVLKYLKNFGYNSRFMNVYIGEECEALV-QLRFADAGEPILVNQMFHITIVNILWRLV 591
RRF L L+NFG R + + EE LV +LR +A P + N++ ++
Sbjct: 4 RRFCLITLRNFGMGKRSIEDRVQEEARCLVEELRKTNA-SPCDPTFILGCAPCNVICSII 62
Query: 592 AGKRYDLXDQRLKKL 636
KR+D DQ+ L
Sbjct: 63 FHKRFDYKDQQFLNL 77
>X54807-1|CAA38578.1| 56|Homo sapiens unspecific monooxygenase
protein.
Length = 56
Score = 34.3 bits (75), Expect = 0.51
Identities = 10/16 (62%), Positives = 15/16 (93%)
Frame = +1
Query: 118 PPGPTPLPVVGNLISV 165
PPGPTPLP++GN++ +
Sbjct: 30 PPGPTPLPIIGNMLQI 45
>AL512656-1|CAI15290.1| 488|Homo sapiens annexin A7 protein.
Length = 488
Score = 34.3 bits (75), Expect = 0.51
Identities = 18/53 (33%), Positives = 26/53 (49%)
Frame = -2
Query: 398 GPSEKTNPSFFPNDLMV*KNPSGLPSNTSRFETSLMSSIPVTTTTLMDPSLKP 240
GP++ P FP M + P G P+ S+ T SS PV + +D S +P
Sbjct: 116 GPAQVPLPGGFPGGQMPSQYPGGQPTYPSQINTDSFSSYPVFSPVSLDYSSEP 168
>AL353731-3|CAI52484.1| 488|Homo sapiens annexin A7 protein.
Length = 488
Score = 34.3 bits (75), Expect = 0.51
Identities = 18/53 (33%), Positives = 26/53 (49%)
Frame = -2
Query: 398 GPSEKTNPSFFPNDLMV*KNPSGLPSNTSRFETSLMSSIPVTTTTLMDPSLKP 240
GP++ P FP M + P G P+ S+ T SS PV + +D S +P
Sbjct: 116 GPAQVPLPGGFPGGQMPSQYPGGQPTYPSQINTDSFSSYPVFSPVSLDYSSEP 168
>BX538127-1|CAD98029.1| 310|Homo sapiens hypothetical protein
protein.
Length = 310
Score = 33.9 bits (74), Expect = 0.68
Identities = 24/75 (32%), Positives = 35/75 (46%), Gaps = 1/75 (1%)
Frame = +1
Query: 415 RRFVLKYLKNFGYNSRFMNVYIGEECEALV-QLRFADAGEPILVNQMFHITIVNILWRLV 591
RRF L L+NFG R + + EE LV +LR +A P + N++ ++
Sbjct: 3 RRFCLMTLRNFGMGKRSIEDRVQEEARCLVEELRKTNA-SPCDPAFILGCAPCNVICSVI 61
Query: 592 AGKRYDLXDQRLKKL 636
R+D DQR L
Sbjct: 62 FHDRFDYKDQRFLNL 76
>D00408-1|BAA00310.1| 503|Homo sapiens cytochrome P-450 HFLa
protein.
Length = 503
Score = 32.3 bits (70), Expect = 2.1
Identities = 45/211 (21%), Positives = 83/211 (39%), Gaps = 8/211 (3%)
Frame = +1
Query: 121 PGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIKE 300
PGPTPLP +GN +S K + +KY + G+ ++ +T ++IK
Sbjct: 39 PGPTPLPFLGNALSFR------KGYWTFDMECYKKYRKVWGIYDCQQPMLAITDPDMIKT 92
Query: 301 VSNREVFEGRPDGFFYTMRSFG----KKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFM 468
V +E + F R FG K + ++ W R R +L G +
Sbjct: 93 VLVKECY-----SVFTNRRPFGPVGFMKNAISIAEDEEWKRIRS-LLSPTFTSGKLKEMV 146
Query: 469 NVYIGEECEALVQ--LRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCN 642
+ I + + LV+ R A+ G+P+ + +F ++++ G D +
Sbjct: 147 PI-IAQYGDVLVRNLRREAETGKPVTLKHVFGAYSMDVITSTSFGVSIDSLNNPQDPFVE 205
Query: 643 LVMRLFKLXDMSGGILNF--LPFLXHFIPRL 729
+L + + +L+ PFL + L
Sbjct: 206 NTKKLLRFNPLDPFVLSIKVFPFLTPILEAL 236
>BC067436-1|AAH67436.1| 503|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 7 protein.
Length = 503
Score = 32.3 bits (70), Expect = 2.1
Identities = 45/211 (21%), Positives = 83/211 (39%), Gaps = 8/211 (3%)
Frame = +1
Query: 121 PGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIKE 300
PGPTPLP +GN +S K + +KY + G+ ++ +T ++IK
Sbjct: 39 PGPTPLPFLGNALSFR------KGYWTFDMECYKKYRKVWGIYDCQQPMLAITDPDMIKT 92
Query: 301 VSNREVFEGRPDGFFYTMRSFG----KKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFM 468
V +E + F R FG K + ++ W R R +L G +
Sbjct: 93 VLVKECY-----SVFTNRRPFGPVGFMKNAISIAEDEEWKRIRS-LLSPTFTSGKLKEMV 146
Query: 469 NVYIGEECEALVQ--LRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCN 642
+ I + + LV+ R A+ G+P+ + +F ++++ G D +
Sbjct: 147 PI-IAQYGDVLVRNLRREAETGKPVTLKHVFGAYSMDVITSTSFGVSIDSLNNPQDPFVE 205
Query: 643 LVMRLFKLXDMSGGILNF--LPFLXHFIPRL 729
+L + + +L+ PFL + L
Sbjct: 206 NTKKLLRFNPLDPFVLSIKVFPFLTPILEAL 236
>AF315325-1|AAG48618.1| 535|Homo sapiens cytochrome P450 variant
3A7 protein.
Length = 535
Score = 32.3 bits (70), Expect = 2.1
Identities = 45/211 (21%), Positives = 83/211 (39%), Gaps = 8/211 (3%)
Frame = +1
Query: 121 PGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIKE 300
PGPTPLP +GN +S K + +KY + G+ ++ +T ++IK
Sbjct: 39 PGPTPLPFLGNALSFR------KGYWTFDMECYKKYRKVWGIYDCQQPMLAITDPDMIKT 92
Query: 301 VSNREVFEGRPDGFFYTMRSFG----KKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFM 468
V +E + F R FG K + ++ W R R +L G +
Sbjct: 93 VLVKECY-----SVFTNRRPFGPVGFMKNAISIAEDEEWKRIRS-LLSPTFTSGKLKEMV 146
Query: 469 NVYIGEECEALVQ--LRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCN 642
+ I + + LV+ R A+ G+P+ + +F ++++ G D +
Sbjct: 147 PI-IAQYGDVLVRNLRREAETGKPVTLKHVFGAYSMDVITSTSFGVSIDSLNNPQDPFVE 205
Query: 643 LVMRLFKLXDMSGGILNF--LPFLXHFIPRL 729
+L + + +L+ PFL + L
Sbjct: 206 NTKKLLRFNPLDPFVLSIKVFPFLTPILEAL 236
>AF280107-3|AAG32289.1| 503|Homo sapiens cytochrome P450
polypeptide 7 protein.
Length = 503
Score = 32.3 bits (70), Expect = 2.1
Identities = 45/211 (21%), Positives = 83/211 (39%), Gaps = 8/211 (3%)
Frame = +1
Query: 121 PGPTPLPVVGNLISVLWESRKFKCHHLIWQSWSQKYGNLLGLRLGSINVVVVTGIELIKE 300
PGPTPLP +GN +S K + +KY + G+ ++ +T ++IK
Sbjct: 39 PGPTPLPFLGNALSFR------KGYWTFDMECYKKYRKVWGIYDCQQPMLAITDPDMIKT 92
Query: 301 VSNREVFEGRPDGFFYTMRSFG----KKLGLVFSDGPTWHRTRRFVLKYLKNFGYNSRFM 468
V +E + F R FG K + ++ W R R +L G +
Sbjct: 93 VLVKECY-----SVFTNRRPFGPVGFMKNAISIAEDEEWKRIRS-LLSPTFTSGKLKEMV 146
Query: 469 NVYIGEECEALVQ--LRFADAGEPILVNQMFHITIVNILWRLVAGKRYDLXDQRLKKLCN 642
+ I + + LV+ R A+ G+P+ + +F ++++ G D +
Sbjct: 147 PI-IAQYGDVLVRNLRREAETGKPVTLKHVFGAYSMDVITSTSFGVSIDSLNNPQDPFVE 205
Query: 643 LVMRLFKLXDMSGGILNF--LPFLXHFIPRL 729
+L + + +L+ PFL + L
Sbjct: 206 NTKKLLRFNPLDPFVLSIKVFPFLTPILEAL 236
>X58906-1|CAA41709.1| 495|Homo sapiens steroid 21-monooxygenase
protein.
Length = 495
Score = 31.9 bits (69), Expect = 2.7
Identities = 37/170 (21%), Positives = 66/170 (38%), Gaps = 3/170 (1%)
Frame = +1
Query: 217 SQKYGNLLGLRLGSINVVVVTGIELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFS 390
+QK+G + L LG +VVV+ I+E V F GRP+ Y + S L
Sbjct: 53 TQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSRNYP-DLSLG 111
Query: 391 DGPTWHRTRRFVLKYLKNFGYNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIV 570
D + + + + G M + + + + A G P+ + + F +
Sbjct: 112 DYSLLWKAHKKLTRSALLLGIRDS-MEPVVEQLTQEFCERMRAQPGTPVAIEEEFSLLTC 170
Query: 571 NILWRLVAGKRYDLXDQRLKKLCNLVMRLFKL-XDMSGGILNFLPFLXHF 717
+I+ L G + D + + + K S I++ +PFL F
Sbjct: 171 SIICYLTFGDKIK-DDNLMPAYYKCIQEVLKTWSHWSIQIVDVIPFLRFF 219
>X58904-1|CAA41707.1| 371|Homo sapiens steroid 21-monooxygenase
protein.
Length = 371
Score = 31.9 bits (69), Expect = 2.7
Identities = 37/170 (21%), Positives = 66/170 (38%), Gaps = 3/170 (1%)
Frame = +1
Query: 217 SQKYGNLLGLRLGSINVVVVTGIELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFS 390
+QK+G + L LG +VVV+ I+E V F GRP+ Y + S L
Sbjct: 52 TQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSRNYP-DLSLG 110
Query: 391 DGPTWHRTRRFVLKYLKNFGYNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIV 570
D + + + + G M + + + + A G P+ + + F +
Sbjct: 111 DYSLLWKAHKKLTRSALLLGIRDS-MEPVVEQLTQEFCERMRAQPGTPVAIEEEFSLLTC 169
Query: 571 NILWRLVAGKRYDLXDQRLKKLCNLVMRLFKL-XDMSGGILNFLPFLXHF 717
+I+ L G + D + + + K S I++ +PFL F
Sbjct: 170 SIICYLTFGDKIK-DDNLMPAYYKCIQEVLKTWSHWSIQIVDVIPFLRFF 218
>X58902-1|CAA41706.1| 372|Homo sapiens steroid 21-monooxygenase
protein.
Length = 372
Score = 31.9 bits (69), Expect = 2.7
Identities = 37/170 (21%), Positives = 66/170 (38%), Gaps = 3/170 (1%)
Frame = +1
Query: 217 SQKYGNLLGLRLGSINVVVVTGIELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFS 390
+QK+G + L LG +VVV+ I+E V F GRP+ Y + S L
Sbjct: 53 TQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSRNYP-DLSLG 111
Query: 391 DGPTWHRTRRFVLKYLKNFGYNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIV 570
D + + + + G M + + + + A G P+ + + F +
Sbjct: 112 DYSLLWKAHKKLTRSALLLGIRDS-MEPVVEQLTQEFCERMRAQPGTPVAIEEEFSLLTC 170
Query: 571 NILWRLVAGKRYDLXDQRLKKLCNLVMRLFKL-XDMSGGILNFLPFLXHF 717
+I+ L G + D + + + K S I++ +PFL F
Sbjct: 171 SIICYLTFGDKIK-DDNLMPAYYKCIQEVLKTWSHWSIQIVDVIPFLRFF 219
>X58900-1|CAA41704.1| 372|Homo sapiens steroid 21-monooxygenase
protein.
Length = 372
Score = 31.9 bits (69), Expect = 2.7
Identities = 37/170 (21%), Positives = 66/170 (38%), Gaps = 3/170 (1%)
Frame = +1
Query: 217 SQKYGNLLGLRLGSINVVVVTGIELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFS 390
+QK+G + L LG +VVV+ I+E V F GRP+ Y + S L
Sbjct: 53 TQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSRNYP-DLSLG 111
Query: 391 DGPTWHRTRRFVLKYLKNFGYNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIV 570
D + + + + G M + + + + A G P+ + + F +
Sbjct: 112 DYSLLWKAHKKLTRSALLLGIRDS-MEPVVEQLTQEFCERMRAQPGTPVAIEEEFSLLTC 170
Query: 571 NILWRLVAGKRYDLXDQRLKKLCNLVMRLFKL-XDMSGGILNFLPFLXHF 717
+I+ L G + D + + + K S I++ +PFL F
Sbjct: 171 SIICYLTFGDKIK-DDNLMPAYYKCIQEVLKTWSHWSIQIVDVIPFLRFF 219
>M28548-1|AAA52065.1| 495|Homo sapiens protein ( Human mutant
21-hydroxylase B gene, complete cds. ).
Length = 495
Score = 31.9 bits (69), Expect = 2.7
Identities = 37/170 (21%), Positives = 66/170 (38%), Gaps = 3/170 (1%)
Frame = +1
Query: 217 SQKYGNLLGLRLGSINVVVVTGIELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFS 390
+QK+G + L LG +VVV+ I+E V F GRP+ Y + S L
Sbjct: 53 TQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSRNYP-DLSLG 111
Query: 391 DGPTWHRTRRFVLKYLKNFGYNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIV 570
D + + + + G M + + + + A G P+ + + F +
Sbjct: 112 DYSLLWKAHKKLTRSALLLGIRDS-MEPVVEQLTQEFCERMRAQPGTPVAIEEEFSLLTC 170
Query: 571 NILWRLVAGKRYDLXDQRLKKLCNLVMRLFKL-XDMSGGILNFLPFLXHF 717
+I+ L G + D + + + K S I++ +PFL F
Sbjct: 171 SIICYLTFGDKIK-DDNLMPAYYKCIQEVLKTWSHWSIQIVDVIPFLRFF 219
>M26856-1|AAA52064.1| 495|Homo sapiens protein ( Human
21-hydroxylase B gene, complete cds. ).
Length = 495
Score = 31.9 bits (69), Expect = 2.7
Identities = 37/170 (21%), Positives = 66/170 (38%), Gaps = 3/170 (1%)
Frame = +1
Query: 217 SQKYGNLLGLRLGSINVVVVTGIELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFS 390
+QK+G + L LG +VVV+ I+E V F GRP+ Y + S L
Sbjct: 53 TQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSRNYP-DLSLG 111
Query: 391 DGPTWHRTRRFVLKYLKNFGYNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIV 570
D + + + + G M + + + + A G P+ + + F +
Sbjct: 112 DYSLLWKAHKKLTRSALLLGIRDS-MEPVVEQLTQEFCERMRAQPGTPVAIEEEFSLLTC 170
Query: 571 NILWRLVAGKRYDLXDQRLKKLCNLVMRLFKL-XDMSGGILNFLPFLXHF 717
+I+ L G + D + + + K S I++ +PFL F
Sbjct: 171 SIICYLTFGDKIK-DDNLMPAYYKCIQEVLKTWSHWSIQIVDVIPFLRFF 219
>M21550-1|AAA52063.1| 495|Homo sapiens CYP21 protein.
Length = 495
Score = 31.9 bits (69), Expect = 2.7
Identities = 37/170 (21%), Positives = 66/170 (38%), Gaps = 3/170 (1%)
Frame = +1
Query: 217 SQKYGNLLGLRLGSINVVVVTGIELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFS 390
+QK+G + L LG +VVV+ I+E V F GRP+ Y + S L
Sbjct: 53 TQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSKNYP-DLSLG 111
Query: 391 DGPTWHRTRRFVLKYLKNFGYNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIV 570
D + + + + G M + + + + A G P+ + + F +
Sbjct: 112 DYSLLWKAHKKLTRSALLLGIRDS-MEPVVEQLTQEFCERMRAQPGTPVAIEEEFSLLTC 170
Query: 571 NILWRLVAGKRYDLXDQRLKKLCNLVMRLFKL-XDMSGGILNFLPFLXHF 717
+I+ L G + D + + + K S I++ +PFL F
Sbjct: 171 SIICYLTFGDKIK-DDNLMPAYYKCIQEVLKTWSHWSIQIVDVIPFLRFF 219
>M13936-1|AAA59695.1| 494|Homo sapiens CYP21P protein.
Length = 494
Score = 31.9 bits (69), Expect = 2.7
Identities = 37/170 (21%), Positives = 66/170 (38%), Gaps = 3/170 (1%)
Frame = +1
Query: 217 SQKYGNLLGLRLGSINVVVVTGIELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFS 390
+QK+G + L LG +VVV+ I+E V F GRP+ Y + S L
Sbjct: 52 TQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSKNYP-DLSLG 110
Query: 391 DGPTWHRTRRFVLKYLKNFGYNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIV 570
D + + + + G M + + + + A G P+ + + F +
Sbjct: 111 DYSLLWKAHKKLTRSALLLGIRDS-MEPVVEQLTQEFCERMRAQPGTPVAIEEEFSLLTC 169
Query: 571 NILWRLVAGKRYDLXDQRLKKLCNLVMRLFKL-XDMSGGILNFLPFLXHF 717
+I+ L G + D + + + K S I++ +PFL F
Sbjct: 170 SIICYLTFGDKIK-DDNLMPAYYKCIQEVLKTWSHWSIQIVDVIPFLRFF 218
>M12792-1|AAB59440.1| 494|Homo sapiens steroid 21-hydroxylase
protein.
Length = 494
Score = 31.9 bits (69), Expect = 2.7
Identities = 37/170 (21%), Positives = 66/170 (38%), Gaps = 3/170 (1%)
Frame = +1
Query: 217 SQKYGNLLGLRLGSINVVVVTGIELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFS 390
+QK+G + L LG +VVV+ I+E V F GRP+ Y + S L
Sbjct: 52 TQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSKNYP-DLSLG 110
Query: 391 DGPTWHRTRRFVLKYLKNFGYNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIV 570
D + + + + G M + + + + A G P+ + + F +
Sbjct: 111 DYSLLWKAHKKLTRSALLLGIRDS-MEPVVEQLTQEFCERMRAQPGTPVAIEEEFSLLTC 169
Query: 571 NILWRLVAGKRYDLXDQRLKKLCNLVMRLFKL-XDMSGGILNFLPFLXHF 717
+I+ L G + D + + + K S I++ +PFL F
Sbjct: 170 SIICYLTFGDKIK-DDNLMPAYYKCIQEVLKTWSHWSIQIVDVIPFLRFF 218
>BX679671-8|CAM26070.1| 494|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 494
Score = 31.9 bits (69), Expect = 2.7
Identities = 37/170 (21%), Positives = 66/170 (38%), Gaps = 3/170 (1%)
Frame = +1
Query: 217 SQKYGNLLGLRLGSINVVVVTGIELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFS 390
+QK+G + L LG +VVV+ I+E V F GRP+ Y + S L
Sbjct: 52 TQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSKNYP-DLSLG 110
Query: 391 DGPTWHRTRRFVLKYLKNFGYNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIV 570
D + + + + G M + + + + A G P+ + + F +
Sbjct: 111 DYSLLWKAHKKLTRSALLLGIRDS-MEPVVEQLTQEFCERMRAQPGTPVAIEEEFSLLTC 169
Query: 571 NILWRLVAGKRYDLXDQRLKKLCNLVMRLFKL-XDMSGGILNFLPFLXHF 717
+I+ L G + D + + + K S I++ +PFL F
Sbjct: 170 SIICYLTFGDKIK-DDNLMPAYYKCIQEVLKTWSHWSIQIVDVIPFLRFF 218
>BC125182-1|AAI25183.1| 494|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 494
Score = 31.9 bits (69), Expect = 2.7
Identities = 37/170 (21%), Positives = 66/170 (38%), Gaps = 3/170 (1%)
Frame = +1
Query: 217 SQKYGNLLGLRLGSINVVVVTGIELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFS 390
+QK+G + L LG +VVV+ I+E V F GRP+ Y + S L
Sbjct: 52 TQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSKNYP-DLSLG 110
Query: 391 DGPTWHRTRRFVLKYLKNFGYNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIV 570
D + + + + G M + + + + A G P+ + + F +
Sbjct: 111 DYSLLWKAHKKLTRSALLLGIRDS-MEPVVEQLTQEFCERMRAQPGTPVAIEEEFSLLTC 169
Query: 571 NILWRLVAGKRYDLXDQRLKKLCNLVMRLFKL-XDMSGGILNFLPFLXHF 717
+I+ L G + D + + + K S I++ +PFL F
Sbjct: 170 SIICYLTFGDKIK-DDNLMPAYYKCIQEVLKTWSHWSIQIVDVIPFLRFF 218
>BC125181-1|AAI25182.1| 495|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 495
Score = 31.9 bits (69), Expect = 2.7
Identities = 37/170 (21%), Positives = 66/170 (38%), Gaps = 3/170 (1%)
Frame = +1
Query: 217 SQKYGNLLGLRLGSINVVVVTGIELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFS 390
+QK+G + L LG +VVV+ I+E V F GRP+ Y + S L
Sbjct: 53 TQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSRNYP-DLSLG 111
Query: 391 DGPTWHRTRRFVLKYLKNFGYNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIV 570
D + + + + G M + + + + A G P+ + + F +
Sbjct: 112 DYSLLWKAHKKLTRSALLLGIRDS-MEPVVEQLTQEFCERMRAQPGTPVAIEEEFSLLTC 170
Query: 571 NILWRLVAGKRYDLXDQRLKKLCNLVMRLFKL-XDMSGGILNFLPFLXHF 717
+I+ L G + D + + + K S I++ +PFL F
Sbjct: 171 SIICYLTFGDKIK-DDNLMPAYYKCIQEVLKTWSHWSIQIVDVIPFLRFF 219
>AM183951-1|CAJ75805.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 31.9 bits (69), Expect = 2.7
Identities = 37/170 (21%), Positives = 66/170 (38%), Gaps = 3/170 (1%)
Frame = +1
Query: 217 SQKYGNLLGLRLGSINVVVVTGIELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFS 390
+QK+G + L LG +VVV+ I+E V F GRP+ Y + S L
Sbjct: 52 TQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSRNYP-DLSLG 110
Query: 391 DGPTWHRTRRFVLKYLKNFGYNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIV 570
D + + + + G M + + + + A G P+ + + F +
Sbjct: 111 DYSLLWKAHKKLTRSALLLGIRDS-MEPVVEQLTQEFCERMRAQPGTPVAIEEEFSLLTC 169
Query: 571 NILWRLVAGKRYDLXDQRLKKLCNLVMRLFKL-XDMSGGILNFLPFLXHF 717
+I+ L G + D + + + K S I++ +PFL F
Sbjct: 170 SIICYLTFGDKIK-DDNLMPAYYKCIQEVLKTWSHWSIQIVDVIPFLRFF 218
>AM183950-1|CAJ75804.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 31.9 bits (69), Expect = 2.7
Identities = 37/170 (21%), Positives = 66/170 (38%), Gaps = 3/170 (1%)
Frame = +1
Query: 217 SQKYGNLLGLRLGSINVVVVTGIELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFS 390
+QK+G + L LG +VVV+ I+E V F GRP+ Y + S L
Sbjct: 52 TQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSRNYP-DLSLG 110
Query: 391 DGPTWHRTRRFVLKYLKNFGYNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIV 570
D + + + + G M + + + + A G P+ + + F +
Sbjct: 111 DYSLLWKAHKKLTRSALLLGIRDS-MEPVVEQLTQEFCERMRAQPGTPVAIEEEFSLLTC 169
Query: 571 NILWRLVAGKRYDLXDQRLKKLCNLVMRLFKL-XDMSGGILNFLPFLXHF 717
+I+ L G + D + + + K S I++ +PFL F
Sbjct: 170 SIICYLTFGDKIK-DDNLMPAYYKCIQEVLKTWSHWSIQIVDVIPFLRFF 218
>AM183949-1|CAJ75803.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 31.9 bits (69), Expect = 2.7
Identities = 37/170 (21%), Positives = 66/170 (38%), Gaps = 3/170 (1%)
Frame = +1
Query: 217 SQKYGNLLGLRLGSINVVVVTGIELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFS 390
+QK+G + L LG +VVV+ I+E V F GRP+ Y + S L
Sbjct: 52 TQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSRNYP-DLSLG 110
Query: 391 DGPTWHRTRRFVLKYLKNFGYNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIV 570
D + + + + G M + + + + A G P+ + + F +
Sbjct: 111 DYSLLWKAHKKLTRSALLLGIRDS-MEPVVEQLTQEFCERMRAQPGTPVAIEEEFSLLTC 169
Query: 571 NILWRLVAGKRYDLXDQRLKKLCNLVMRLFKL-XDMSGGILNFLPFLXHF 717
+I+ L G + D + + + K S I++ +PFL F
Sbjct: 170 SIICYLTFGDKIK-DDNLMPAYYKCIQEVLKTWSHWSIQIVDVIPFLRFF 218
>AM183948-1|CAJ75802.1| 494|Homo sapiens steroid 21-hydroxylase
protein.
Length = 494
Score = 31.9 bits (69), Expect = 2.7
Identities = 37/170 (21%), Positives = 66/170 (38%), Gaps = 3/170 (1%)
Frame = +1
Query: 217 SQKYGNLLGLRLGSINVVVVTGIELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFS 390
+QK+G + L LG +VVV+ I+E V F GRP+ Y + S L
Sbjct: 52 TQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSRNYP-DLSLG 110
Query: 391 DGPTWHRTRRFVLKYLKNFGYNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIV 570
D + + + + G M + + + + A G P+ + + F +
Sbjct: 111 DYSLLWKAHKKLTRSALLLGIRDS-MEPVVEQLTQEFCERMRAQPGTPVAIEEEFSLLTC 169
Query: 571 NILWRLVAGKRYDLXDQRLKKLCNLVMRLFKL-XDMSGGILNFLPFLXHF 717
+I+ L G + D + + + K S I++ +PFL F
Sbjct: 170 SIICYLTFGDKIK-DDNLMPAYYKCIQEVLKTWSHWSIQIVDVIPFLRFF 218
>AM183947-1|CAJ75801.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 31.9 bits (69), Expect = 2.7
Identities = 37/170 (21%), Positives = 66/170 (38%), Gaps = 3/170 (1%)
Frame = +1
Query: 217 SQKYGNLLGLRLGSINVVVVTGIELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFS 390
+QK+G + L LG +VVV+ I+E V F GRP+ Y + S L
Sbjct: 52 TQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSRNYP-DLSLG 110
Query: 391 DGPTWHRTRRFVLKYLKNFGYNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIV 570
D + + + + G M + + + + A G P+ + + F +
Sbjct: 111 DYSLLWKAHKKLTRSALLLGIRDS-MEPVVEQLTQEFCERMRAQPGTPVAIEEEFSLLTC 169
Query: 571 NILWRLVAGKRYDLXDQRLKKLCNLVMRLFKL-XDMSGGILNFLPFLXHF 717
+I+ L G + D + + + K S I++ +PFL F
Sbjct: 170 SIICYLTFGDKIK-DDNLMPAYYKCIQEVLKTWSHWSIQIVDVIPFLRFF 218
>AM086565-1|CAJ31104.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 31.9 bits (69), Expect = 2.7
Identities = 37/170 (21%), Positives = 66/170 (38%), Gaps = 3/170 (1%)
Frame = +1
Query: 217 SQKYGNLLGLRLGSINVVVVTGIELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFS 390
+QK+G + L LG +VVV+ I+E V F GRP+ Y + S L
Sbjct: 52 TQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSRNYP-DLSLG 110
Query: 391 DGPTWHRTRRFVLKYLKNFGYNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIV 570
D + + + + G M + + + + A G P+ + + F +
Sbjct: 111 DYSLLWKAHKKLTRSALLLGIRDS-MEPVVEQLTQEFCERMRAQPGTPVAIEEEFSLLTC 169
Query: 571 NILWRLVAGKRYDLXDQRLKKLCNLVMRLFKL-XDMSGGILNFLPFLXHF 717
+I+ L G + D + + + K S I++ +PFL F
Sbjct: 170 SIICYLTFGDKIK-DDNLMPAYYKCIQEVLKTWSHWSIQIVDVIPFLRFF 218
>AL929593-1|CAI41779.1| 495|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 495
Score = 31.9 bits (69), Expect = 2.7
Identities = 37/170 (21%), Positives = 66/170 (38%), Gaps = 3/170 (1%)
Frame = +1
Query: 217 SQKYGNLLGLRLGSINVVVVTGIELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFS 390
+QK+G + L LG +VVV+ I+E V F GRP+ Y + S L
Sbjct: 53 TQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSRNYP-DLSLG 111
Query: 391 DGPTWHRTRRFVLKYLKNFGYNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIV 570
D + + + + G M + + + + A G P+ + + F +
Sbjct: 112 DYSLLWKAHKKLTRSALLLGIRDS-MEPVVEQLTQEFCERMRAQPGTPVAIEEEFSLLTC 170
Query: 571 NILWRLVAGKRYDLXDQRLKKLCNLVMRLFKL-XDMSGGILNFLPFLXHF 717
+I+ L G + D + + + K S I++ +PFL F
Sbjct: 171 SIICYLTFGDKIK-DDNLMPAYYKCIQEVLKTWSHWSIQIVDVIPFLRFF 219
>AL662849-18|CAI17479.1| 495|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 495
Score = 31.9 bits (69), Expect = 2.7
Identities = 37/170 (21%), Positives = 66/170 (38%), Gaps = 3/170 (1%)
Frame = +1
Query: 217 SQKYGNLLGLRLGSINVVVVTGIELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFS 390
+QK+G + L LG +VVV+ I+E V F GRP+ Y + S L
Sbjct: 53 TQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSRNYP-DLSLG 111
Query: 391 DGPTWHRTRRFVLKYLKNFGYNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIV 570
D + + + + G M + + + + A G P+ + + F +
Sbjct: 112 DYSLLWKAHKKLTRSALLLGIRDS-MEPVVEQLTQEFCERMRAQPGTPVAIEEEFSLLTC 170
Query: 571 NILWRLVAGKRYDLXDQRLKKLCNLVMRLFKL-XDMSGGILNFLPFLXHF 717
+I+ L G + D + + + K S I++ +PFL F
Sbjct: 171 SIICYLTFGDKIK-DDNLMPAYYKCIQEVLKTWSHWSIQIVDVIPFLRFF 219
>AL645922-24|CAI41754.1| 495|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 495
Score = 31.9 bits (69), Expect = 2.7
Identities = 37/170 (21%), Positives = 66/170 (38%), Gaps = 3/170 (1%)
Frame = +1
Query: 217 SQKYGNLLGLRLGSINVVVVTGIELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFS 390
+QK+G + L LG +VVV+ I+E V F GRP+ Y + S L
Sbjct: 53 TQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSRNYP-DLSLG 111
Query: 391 DGPTWHRTRRFVLKYLKNFGYNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIV 570
D + + + + G M + + + + A G P+ + + F +
Sbjct: 112 DYSLLWKAHKKLTRSALLLGIRDS-MEPVVEQLTQEFCERMRAQPGTPVAIEEEFSLLTC 170
Query: 571 NILWRLVAGKRYDLXDQRLKKLCNLVMRLFKL-XDMSGGILNFLPFLXHF 717
+I+ L G + D + + + K S I++ +PFL F
Sbjct: 171 SIICYLTFGDKIK-DDNLMPAYYKCIQEVLKTWSHWSIQIVDVIPFLRFF 219
>AL049547-7|CAB89301.1| 495|Homo sapiens dJ34F7.3 (cytochrome P450,
subfamily XXIA (steroid 21-hydroxylase, congenital a
protein.
Length = 495
Score = 31.9 bits (69), Expect = 2.7
Identities = 37/170 (21%), Positives = 66/170 (38%), Gaps = 3/170 (1%)
Frame = +1
Query: 217 SQKYGNLLGLRLGSINVVVVTGIELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFS 390
+QK+G + L LG +VVV+ I+E V F GRP+ Y + S L
Sbjct: 53 TQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSRNYP-DLSLG 111
Query: 391 DGPTWHRTRRFVLKYLKNFGYNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIV 570
D + + + + G M + + + + A G P+ + + F +
Sbjct: 112 DYSLLWKAHKKLTRSALLLGIRDS-MEPVVEQLTQEFCERMRAQPGTPVAIEEEFSLLTC 170
Query: 571 NILWRLVAGKRYDLXDQRLKKLCNLVMRLFKL-XDMSGGILNFLPFLXHF 717
+I+ L G + D + + + K S I++ +PFL F
Sbjct: 171 SIICYLTFGDKIK-DDNLMPAYYKCIQEVLKTWSHWSIQIVDVIPFLRFF 219
>AF019413-2|AAB67982.1| 495|Homo sapiens cytochrome P450
21-hydroxylase protein.
Length = 495
Score = 31.9 bits (69), Expect = 2.7
Identities = 37/170 (21%), Positives = 66/170 (38%), Gaps = 3/170 (1%)
Frame = +1
Query: 217 SQKYGNLLGLRLGSINVVVVTGIELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFS 390
+QK+G + L LG +VVV+ I+E V F GRP+ Y + S L
Sbjct: 53 TQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSRNYP-DLSLG 111
Query: 391 DGPTWHRTRRFVLKYLKNFGYNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIV 570
D + + + + G M + + + + A G P+ + + F +
Sbjct: 112 DYSLLWKAHKKLTRSALLLGIRDS-MEPVVEQLTQEFCERMRAQPGTPVAIEEEFSLLTC 170
Query: 571 NILWRLVAGKRYDLXDQRLKKLCNLVMRLFKL-XDMSGGILNFLPFLXHF 717
+I+ L G + D + + + K S I++ +PFL F
Sbjct: 171 SIICYLTFGDKIK-DDNLMPAYYKCIQEVLKTWSHWSIQIVDVIPFLRFF 219
>AM183946-1|CAJ75800.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 31.1 bits (67), Expect = 4.8
Identities = 37/170 (21%), Positives = 66/170 (38%), Gaps = 3/170 (1%)
Frame = +1
Query: 217 SQKYGNLLGLRLGSINVVVVTGIELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFS 390
+QK+G + L LG +VVV+ I+E V F GRP+ Y + S L
Sbjct: 52 TQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSRNYP-DLSLG 110
Query: 391 DGPTWHRTRRFVLKYLKNFGYNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIV 570
D + + + + G M + + + + A G P+ + + F +
Sbjct: 111 DYSLLWKAHKKLTRSALLLGIRDS-MEPVVEQLTQEFRERMRAQPGTPVAIEEEFSLLTC 169
Query: 571 NILWRLVAGKRYDLXDQRLKKLCNLVMRLFKL-XDMSGGILNFLPFLXHF 717
+I+ L G + D + + + K S I++ +PFL F
Sbjct: 170 SIICYLTFGDKIK-DDNLMPAYYKCIQEVLKTWSHWSIQIVDVIPFLRFF 218
>AM183945-1|CAJ75799.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 30.7 bits (66), Expect = 6.3
Identities = 39/170 (22%), Positives = 66/170 (38%), Gaps = 3/170 (1%)
Frame = +1
Query: 217 SQKYGNLLGLRLGSINVVVVTGIELIKE--VSNREVFEGRPDGFFYTMRSFGKKLGLVFS 390
+QK+G + L LG +VVV+ I+E V F GRP+ Y + S L
Sbjct: 52 TQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSRNYP-DLSLG 110
Query: 391 DGPTWHRTRRFVLKYLKNFGYNSRFMNVYIGEECEALVQLRFADAGEPILVNQMFHITIV 570
D + + + + G V E ++R A G P+ + + F +
Sbjct: 111 DYSLLWKAHKKLTRSALLLGIRDSMEPVEEQLTQEFCERMR-AQPGTPVAIEEEFSLLTC 169
Query: 571 NILWRLVAGKRYDLXDQRLKKLCNLVMRLFKL-XDMSGGILNFLPFLXHF 717
+I+ L G + D + + + K S I++ +PFL F
Sbjct: 170 SIICYLTFGDKIK-DDNLMPAYYKCIQEVLKTWSHWSIQIVDVIPFLRFF 218
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 122,910,802
Number of Sequences: 237096
Number of extensions: 2839659
Number of successful extensions: 6390
Number of sequences better than 10.0: 253
Number of HSP's better than 10.0 without gapping: 5786
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6151
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 9757565650
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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