Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P12_F_H19
(722 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X17094-1|CAA34948.1| 794|Homo sapiens protein ( Human fur mRNA ... 99 2e-20
X15723-1|CAA33745.1| 280|Homo sapiens furin protein. 99 2e-20
BC012181-1|AAH12181.1| 794|Homo sapiens furin (paired basic ami... 99 2e-20
M80482-1|AAA59998.1| 969|Homo sapiens subtilisin-like protease ... 71 6e-12
D87995-1|BAA21793.1| 956|Homo sapiens PACE4A-II protein. 71 6e-12
D87994-1|BAA21792.1| 962|Homo sapiens PACE4E-II protein. 71 6e-12
D87993-1|BAA21791.1| 975|Homo sapiens PACE4E-I protein. 71 6e-12
D28513-1|BAA05871.1| 652|Homo sapiens kexin-like protease protein. 71 6e-12
AB001914-7|BAA21620.1| 487|Homo sapiens PACE4B protein. 71 6e-12
AB001914-6|BAA21623.1| 623|Homo sapiens PACE4CS protein. 71 6e-12
AB001914-5|BAA21621.1| 652|Homo sapiens PACE4C protein. 71 6e-12
AB001914-4|BAA21627.1| 975|Homo sapiens PACE4E-I protein. 71 6e-12
AB001914-3|BAA21626.1| 962|Homo sapiens PACE4E-II protein. 71 6e-12
AB001914-2|BAA21625.1| 956|Homo sapiens PACE4A-II protein. 71 6e-12
AB001914-1|BAA21624.1| 969|Homo sapiens PACE4A-I protein. 71 6e-12
U56387-1|AAC50643.2| 913|Homo sapiens protease PC6 isoform A pr... 69 2e-11
U49114-1|AAA91807.1| 899|Homo sapiens prohormone convertase 5 p... 69 2e-11
BC012064-1|AAH12064.1| 913|Homo sapiens proprotein convertase s... 69 2e-11
AL359253-2|CAH73743.1| 913|Homo sapiens proprotein convertase s... 69 2e-11
AL359253-1|CAH73742.1| 690|Homo sapiens proprotein convertase s... 69 2e-11
AL353607-2|CAI41233.1| 913|Homo sapiens proprotein convertase s... 69 2e-11
AL353607-1|CAI41232.1| 690|Homo sapiens proprotein convertase s... 69 2e-11
AY358963-1|AAQ89322.1| 755|Homo sapiens prohormone convertase p... 68 4e-11
X64810-1|CAA46031.1| 753|Homo sapiens PC1/PC3 protein. 61 1e-10
M90753-1|AAA59918.1| 753|Homo sapiens PC1 protein. 61 1e-10
D73407-1|BAA11133.1| 753|Homo sapiens prohormone convertase 3 p... 61 1e-10
BC130295-1|AAI30296.1| 753|Homo sapiens proprotein convertase s... 61 1e-10
AB208874-1|BAD92111.1| 724|Homo sapiens proprotein convertase s... 61 1e-10
AM491522-1|CAM33226.1| 357|Homo sapiens proprotein convertase s... 60 6e-09
M95971-1|AAA59919.1| 638|Homo sapiens neuroendocrine convertase... 50 2e-06
J05252-1|AAA60032.1| 638|Homo sapiens endoprotease protein. 50 2e-06
BC005815-1|AAH05815.1| 638|Homo sapiens proprotein convertase s... 50 2e-06
AL359511-2|CAI20085.1| 638|Homo sapiens proprotein convertase s... 50 2e-06
AL121779-1|CAI19155.1| 638|Homo sapiens proprotein convertase s... 50 2e-06
AL031675-1|CAI22648.1| 638|Homo sapiens proprotein convertase s... 50 2e-06
AL031664-2|CAI21690.1| 638|Homo sapiens proprotein convertase s... 50 2e-06
BC040546-1|AAH40546.1| 619|Homo sapiens PCSK2 protein protein. 50 2e-06
AL359511-3|CAC34957.2| 619|Homo sapiens proprotein convertase s... 50 2e-06
AL121779-2|CAB96732.2| 619|Homo sapiens proprotein convertase s... 50 2e-06
AL031675-2|CAA21069.2| 619|Homo sapiens proprotein convertase s... 50 2e-06
AL031664-3|CAB89428.2| 619|Homo sapiens proprotein convertase s... 50 2e-06
AB208955-1|BAD92192.1| 800|Homo sapiens paired basic amino acid... 47 6e-05
BT006870-1|AAP35516.1| 785|Homo sapiens proprotein convertase s... 39 0.021
BC010696-1|AAH10696.1| 785|Homo sapiens proprotein convertase s... 39 0.021
BC006357-1|AAH06357.1| 591|Homo sapiens PCSK7 protein protein. 39 0.021
AK222907-1|BAD96627.1| 785|Homo sapiens proprotein convertase s... 39 0.021
U40623-1|AAC50417.1| 785|Homo sapiens PC8 precursor protein. 36 0.19
U33849-1|AAB03087.1| 785|Homo sapiens lymphoma proprotein conve... 36 0.19
D29677-1|BAA06147.2| 1943|Homo sapiens KIAA0054 protein. 30 7.3
BC130582-1|AAI30583.1| 1942|Homo sapiens helicase with zinc fing... 30 7.3
Y00508-1|CAA68560.1| 460|Homo sapiens muscarinic acetylcholine ... 30 9.6
X52068-1|CAA36291.1| 460|Homo sapiens protein ( Human gene for ... 30 9.6
X15263-1|CAA33334.1| 460|Homo sapiens protein ( Human gene for ... 30 9.6
BT007166-1|AAP35830.1| 460|Homo sapiens cholinergic receptor, m... 30 9.6
BC022984-1|AAH22984.1| 460|Homo sapiens cholinergic receptor, m... 30 9.6
BC007740-1|AAH07740.1| 460|Homo sapiens cholinergic receptor, m... 30 9.6
AF498915-1|AAM18938.1| 460|Homo sapiens muscarinic acetylcholin... 30 9.6
AF385587-1|AAK68112.1| 454|Homo sapiens m1 muscarinic cholinerg... 30 9.6
>X17094-1|CAA34948.1| 794|Homo sapiens protein ( Human fur mRNA for
furin. ).
Length = 794
Score = 98.7 bits (235), Expect = 2e-20
Identities = 44/79 (55%), Positives = 56/79 (70%)
Frame = +1
Query: 286 YTPTWAVHIPEGREVADAVARDHGFVNLGKIFDDHYHFHHRSLTKRSLTAAHEHHGRLEG 465
+T TWAV IP G VA++VAR HGF+NLG+IF D+YHF HR +TKRSL+ H RL+
Sbjct: 30 FTNTWAVRIPGGPAVANSVARKHGFLNLGQIFGDYYHFWHRGVTKRSLSPHRPRHSRLQR 89
Query: 466 DSRVRWAEQQKILSRKKRD 522
+ +V+W EQQ R KRD
Sbjct: 90 EPQVQWLEQQVAKRRTKRD 108
>X15723-1|CAA33745.1| 280|Homo sapiens furin protein.
Length = 280
Score = 98.7 bits (235), Expect = 2e-20
Identities = 44/79 (55%), Positives = 56/79 (70%)
Frame = +1
Query: 286 YTPTWAVHIPEGREVADAVARDHGFVNLGKIFDDHYHFHHRSLTKRSLTAAHEHHGRLEG 465
+T TWAV IP G VA++VAR HGF+NLG+IF D+YHF HR +TKRSL+ H RL+
Sbjct: 30 FTNTWAVRIPGGPAVANSVARKHGFLNLGQIFGDYYHFWHRGVTKRSLSPHRPRHSRLQR 89
Query: 466 DSRVRWAEQQKILSRKKRD 522
+ +V+W EQQ R KRD
Sbjct: 90 EPQVQWLEQQVAKRRTKRD 108
>BC012181-1|AAH12181.1| 794|Homo sapiens furin (paired basic amino
acid cleaving enzyme) protein.
Length = 794
Score = 98.7 bits (235), Expect = 2e-20
Identities = 44/79 (55%), Positives = 56/79 (70%)
Frame = +1
Query: 286 YTPTWAVHIPEGREVADAVARDHGFVNLGKIFDDHYHFHHRSLTKRSLTAAHEHHGRLEG 465
+T TWAV IP G VA++VAR HGF+NLG+IF D+YHF HR +TKRSL+ H RL+
Sbjct: 30 FTNTWAVRIPGGPAVANSVARKHGFLNLGQIFGDYYHFWHRGVTKRSLSPHRPRHSRLQR 89
Query: 466 DSRVRWAEQQKILSRKKRD 522
+ +V+W EQQ R KRD
Sbjct: 90 EPQVQWLEQQVAKRRTKRD 108
>M80482-1|AAA59998.1| 969|Homo sapiens subtilisin-like protease
protein.
Length = 969
Score = 70.5 bits (165), Expect = 6e-12
Identities = 34/80 (42%), Positives = 48/80 (60%), Gaps = 2/80 (2%)
Frame = +1
Query: 286 YTPTWAVHIPEGREVADAVARDHGFVNLGKI--FDDHYHFHHRSLTKRSLTAAHEHHGRL 459
YT WAV + G AD VA HG++NLG+I +D+YHF+H KRS ++ H L
Sbjct: 70 YTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDYYHFYHSKTFKRSTLSSRGPHTFL 129
Query: 460 EGDSRVRWAEQQKILSRKKR 519
D +V+W +QQ++ R KR
Sbjct: 130 RMDPQVKWLQQQEVKRRVKR 149
Score = 31.5 bits (68), Expect = 3.2
Identities = 12/35 (34%), Positives = 19/35 (54%)
Frame = +1
Query: 613 KRXLNTRIRGXTRSADLKFILNDPKWPHMWYLNRG 717
++ + R++ RS NDP W +MWYL+ G
Sbjct: 140 QQEVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCG 174
>D87995-1|BAA21793.1| 956|Homo sapiens PACE4A-II protein.
Length = 956
Score = 70.5 bits (165), Expect = 6e-12
Identities = 34/80 (42%), Positives = 48/80 (60%), Gaps = 2/80 (2%)
Frame = +1
Query: 286 YTPTWAVHIPEGREVADAVARDHGFVNLGKI--FDDHYHFHHRSLTKRSLTAAHEHHGRL 459
YT WAV + G AD VA HG++NLG+I +D+YHF+H KRS ++ H L
Sbjct: 70 YTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDYYHFYHSKTFKRSTLSSRGPHTFL 129
Query: 460 EGDSRVRWAEQQKILSRKKR 519
D +V+W +QQ++ R KR
Sbjct: 130 RMDPQVKWLQQQEVKRRVKR 149
Score = 31.5 bits (68), Expect = 3.2
Identities = 12/35 (34%), Positives = 19/35 (54%)
Frame = +1
Query: 613 KRXLNTRIRGXTRSADLKFILNDPKWPHMWYLNRG 717
++ + R++ RS NDP W +MWYL+ G
Sbjct: 140 QQEVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCG 174
>D87994-1|BAA21792.1| 962|Homo sapiens PACE4E-II protein.
Length = 962
Score = 70.5 bits (165), Expect = 6e-12
Identities = 34/80 (42%), Positives = 48/80 (60%), Gaps = 2/80 (2%)
Frame = +1
Query: 286 YTPTWAVHIPEGREVADAVARDHGFVNLGKI--FDDHYHFHHRSLTKRSLTAAHEHHGRL 459
YT WAV + G AD VA HG++NLG+I +D+YHF+H KRS ++ H L
Sbjct: 70 YTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDYYHFYHSKTFKRSTLSSRGPHTFL 129
Query: 460 EGDSRVRWAEQQKILSRKKR 519
D +V+W +QQ++ R KR
Sbjct: 130 RMDPQVKWLQQQEVKRRVKR 149
Score = 31.5 bits (68), Expect = 3.2
Identities = 12/35 (34%), Positives = 19/35 (54%)
Frame = +1
Query: 613 KRXLNTRIRGXTRSADLKFILNDPKWPHMWYLNRG 717
++ + R++ RS NDP W +MWYL+ G
Sbjct: 140 QQEVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCG 174
>D87993-1|BAA21791.1| 975|Homo sapiens PACE4E-I protein.
Length = 975
Score = 70.5 bits (165), Expect = 6e-12
Identities = 34/80 (42%), Positives = 48/80 (60%), Gaps = 2/80 (2%)
Frame = +1
Query: 286 YTPTWAVHIPEGREVADAVARDHGFVNLGKI--FDDHYHFHHRSLTKRSLTAAHEHHGRL 459
YT WAV + G AD VA HG++NLG+I +D+YHF+H KRS ++ H L
Sbjct: 70 YTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDYYHFYHSKTFKRSTLSSRGPHTFL 129
Query: 460 EGDSRVRWAEQQKILSRKKR 519
D +V+W +QQ++ R KR
Sbjct: 130 RMDPQVKWLQQQEVKRRVKR 149
Score = 31.5 bits (68), Expect = 3.2
Identities = 12/35 (34%), Positives = 19/35 (54%)
Frame = +1
Query: 613 KRXLNTRIRGXTRSADLKFILNDPKWPHMWYLNRG 717
++ + R++ RS NDP W +MWYL+ G
Sbjct: 140 QQEVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCG 174
>D28513-1|BAA05871.1| 652|Homo sapiens kexin-like protease protein.
Length = 652
Score = 70.5 bits (165), Expect = 6e-12
Identities = 34/80 (42%), Positives = 48/80 (60%), Gaps = 2/80 (2%)
Frame = +1
Query: 286 YTPTWAVHIPEGREVADAVARDHGFVNLGKI--FDDHYHFHHRSLTKRSLTAAHEHHGRL 459
YT WAV + G AD VA HG++NLG+I +D+YHF+H KRS ++ H L
Sbjct: 70 YTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDYYHFYHSKTFKRSTLSSRGPHTFL 129
Query: 460 EGDSRVRWAEQQKILSRKKR 519
D +V+W +QQ++ R KR
Sbjct: 130 RMDPQVKWLQQQEVKRRVKR 149
Score = 31.5 bits (68), Expect = 3.2
Identities = 12/35 (34%), Positives = 19/35 (54%)
Frame = +1
Query: 613 KRXLNTRIRGXTRSADLKFILNDPKWPHMWYLNRG 717
++ + R++ RS NDP W +MWYL+ G
Sbjct: 140 QQEVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCG 174
>AB001914-7|BAA21620.1| 487|Homo sapiens PACE4B protein.
Length = 487
Score = 70.5 bits (165), Expect = 6e-12
Identities = 34/80 (42%), Positives = 48/80 (60%), Gaps = 2/80 (2%)
Frame = +1
Query: 286 YTPTWAVHIPEGREVADAVARDHGFVNLGKI--FDDHYHFHHRSLTKRSLTAAHEHHGRL 459
YT WAV + G AD VA HG++NLG+I +D+YHF+H KRS ++ H L
Sbjct: 70 YTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDYYHFYHSKTFKRSTLSSRGPHTFL 129
Query: 460 EGDSRVRWAEQQKILSRKKR 519
D +V+W +QQ++ R KR
Sbjct: 130 RMDPQVKWLQQQEVKRRVKR 149
Score = 31.5 bits (68), Expect = 3.2
Identities = 12/35 (34%), Positives = 19/35 (54%)
Frame = +1
Query: 613 KRXLNTRIRGXTRSADLKFILNDPKWPHMWYLNRG 717
++ + R++ RS NDP W +MWYL+ G
Sbjct: 140 QQEVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCG 174
>AB001914-6|BAA21623.1| 623|Homo sapiens PACE4CS protein.
Length = 623
Score = 70.5 bits (165), Expect = 6e-12
Identities = 34/80 (42%), Positives = 48/80 (60%), Gaps = 2/80 (2%)
Frame = +1
Query: 286 YTPTWAVHIPEGREVADAVARDHGFVNLGKI--FDDHYHFHHRSLTKRSLTAAHEHHGRL 459
YT WAV + G AD VA HG++NLG+I +D+YHF+H KRS ++ H L
Sbjct: 70 YTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDYYHFYHSKTFKRSTLSSRGPHTFL 129
Query: 460 EGDSRVRWAEQQKILSRKKR 519
D +V+W +QQ++ R KR
Sbjct: 130 RMDPQVKWLQQQEVKRRVKR 149
Score = 31.5 bits (68), Expect = 3.2
Identities = 12/35 (34%), Positives = 19/35 (54%)
Frame = +1
Query: 613 KRXLNTRIRGXTRSADLKFILNDPKWPHMWYLNRG 717
++ + R++ RS NDP W +MWYL+ G
Sbjct: 140 QQEVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCG 174
>AB001914-5|BAA21621.1| 652|Homo sapiens PACE4C protein.
Length = 652
Score = 70.5 bits (165), Expect = 6e-12
Identities = 34/80 (42%), Positives = 48/80 (60%), Gaps = 2/80 (2%)
Frame = +1
Query: 286 YTPTWAVHIPEGREVADAVARDHGFVNLGKI--FDDHYHFHHRSLTKRSLTAAHEHHGRL 459
YT WAV + G AD VA HG++NLG+I +D+YHF+H KRS ++ H L
Sbjct: 70 YTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDYYHFYHSKTFKRSTLSSRGPHTFL 129
Query: 460 EGDSRVRWAEQQKILSRKKR 519
D +V+W +QQ++ R KR
Sbjct: 130 RMDPQVKWLQQQEVKRRVKR 149
Score = 31.5 bits (68), Expect = 3.2
Identities = 12/35 (34%), Positives = 19/35 (54%)
Frame = +1
Query: 613 KRXLNTRIRGXTRSADLKFILNDPKWPHMWYLNRG 717
++ + R++ RS NDP W +MWYL+ G
Sbjct: 140 QQEVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCG 174
>AB001914-4|BAA21627.1| 975|Homo sapiens PACE4E-I protein.
Length = 975
Score = 70.5 bits (165), Expect = 6e-12
Identities = 34/80 (42%), Positives = 48/80 (60%), Gaps = 2/80 (2%)
Frame = +1
Query: 286 YTPTWAVHIPEGREVADAVARDHGFVNLGKI--FDDHYHFHHRSLTKRSLTAAHEHHGRL 459
YT WAV + G AD VA HG++NLG+I +D+YHF+H KRS ++ H L
Sbjct: 70 YTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDYYHFYHSKTFKRSTLSSRGPHTFL 129
Query: 460 EGDSRVRWAEQQKILSRKKR 519
D +V+W +QQ++ R KR
Sbjct: 130 RMDPQVKWLQQQEVKRRVKR 149
Score = 31.5 bits (68), Expect = 3.2
Identities = 12/35 (34%), Positives = 19/35 (54%)
Frame = +1
Query: 613 KRXLNTRIRGXTRSADLKFILNDPKWPHMWYLNRG 717
++ + R++ RS NDP W +MWYL+ G
Sbjct: 140 QQEVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCG 174
>AB001914-3|BAA21626.1| 962|Homo sapiens PACE4E-II protein.
Length = 962
Score = 70.5 bits (165), Expect = 6e-12
Identities = 34/80 (42%), Positives = 48/80 (60%), Gaps = 2/80 (2%)
Frame = +1
Query: 286 YTPTWAVHIPEGREVADAVARDHGFVNLGKI--FDDHYHFHHRSLTKRSLTAAHEHHGRL 459
YT WAV + G AD VA HG++NLG+I +D+YHF+H KRS ++ H L
Sbjct: 70 YTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDYYHFYHSKTFKRSTLSSRGPHTFL 129
Query: 460 EGDSRVRWAEQQKILSRKKR 519
D +V+W +QQ++ R KR
Sbjct: 130 RMDPQVKWLQQQEVKRRVKR 149
Score = 31.5 bits (68), Expect = 3.2
Identities = 12/35 (34%), Positives = 19/35 (54%)
Frame = +1
Query: 613 KRXLNTRIRGXTRSADLKFILNDPKWPHMWYLNRG 717
++ + R++ RS NDP W +MWYL+ G
Sbjct: 140 QQEVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCG 174
>AB001914-2|BAA21625.1| 956|Homo sapiens PACE4A-II protein.
Length = 956
Score = 70.5 bits (165), Expect = 6e-12
Identities = 34/80 (42%), Positives = 48/80 (60%), Gaps = 2/80 (2%)
Frame = +1
Query: 286 YTPTWAVHIPEGREVADAVARDHGFVNLGKI--FDDHYHFHHRSLTKRSLTAAHEHHGRL 459
YT WAV + G AD VA HG++NLG+I +D+YHF+H KRS ++ H L
Sbjct: 70 YTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDYYHFYHSKTFKRSTLSSRGPHTFL 129
Query: 460 EGDSRVRWAEQQKILSRKKR 519
D +V+W +QQ++ R KR
Sbjct: 130 RMDPQVKWLQQQEVKRRVKR 149
Score = 31.5 bits (68), Expect = 3.2
Identities = 12/35 (34%), Positives = 19/35 (54%)
Frame = +1
Query: 613 KRXLNTRIRGXTRSADLKFILNDPKWPHMWYLNRG 717
++ + R++ RS NDP W +MWYL+ G
Sbjct: 140 QQEVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCG 174
>AB001914-1|BAA21624.1| 969|Homo sapiens PACE4A-I protein.
Length = 969
Score = 70.5 bits (165), Expect = 6e-12
Identities = 34/80 (42%), Positives = 48/80 (60%), Gaps = 2/80 (2%)
Frame = +1
Query: 286 YTPTWAVHIPEGREVADAVARDHGFVNLGKI--FDDHYHFHHRSLTKRSLTAAHEHHGRL 459
YT WAV + G AD VA HG++NLG+I +D+YHF+H KRS ++ H L
Sbjct: 70 YTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDYYHFYHSKTFKRSTLSSRGPHTFL 129
Query: 460 EGDSRVRWAEQQKILSRKKR 519
D +V+W +QQ++ R KR
Sbjct: 130 RMDPQVKWLQQQEVKRRVKR 149
Score = 31.5 bits (68), Expect = 3.2
Identities = 12/35 (34%), Positives = 19/35 (54%)
Frame = +1
Query: 613 KRXLNTRIRGXTRSADLKFILNDPKWPHMWYLNRG 717
++ + R++ RS NDP W +MWYL+ G
Sbjct: 140 QQEVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCG 174
>U56387-1|AAC50643.2| 913|Homo sapiens protease PC6 isoform A
protein.
Length = 913
Score = 68.5 bits (160), Expect = 2e-11
Identities = 31/82 (37%), Positives = 48/82 (58%), Gaps = 2/82 (2%)
Frame = +1
Query: 286 YTPTWAVHIPEGREVADAVARDHGFVNLGKI--FDDHYHFHHRSLTKRSLTAAHEHHGRL 459
YT WAV I G A+ +A +GF+N+G+I D+YHF+H KRS+ ++ H +
Sbjct: 35 YTNHWAVKIAGGFPEANRIASKYGFINIGQIGALKDYYHFYHSRTIKRSVISSRGTHSFI 94
Query: 460 EGDSRVRWAEQQKILSRKKRDF 525
+ +V W +QQ + R KRD+
Sbjct: 95 SMEPKVEWIQQQVVKKRTKRDY 116
Score = 31.1 bits (67), Expect = 4.2
Identities = 9/12 (75%), Positives = 11/12 (91%)
Frame = +1
Query: 676 NDPKWPHMWYLN 711
NDPKWP MWY++
Sbjct: 127 NDPKWPSMWYMH 138
>U49114-1|AAA91807.1| 899|Homo sapiens prohormone convertase 5
precursor protein.
Length = 899
Score = 68.5 bits (160), Expect = 2e-11
Identities = 31/82 (37%), Positives = 48/82 (58%), Gaps = 2/82 (2%)
Frame = +1
Query: 286 YTPTWAVHIPEGREVADAVARDHGFVNLGKI--FDDHYHFHHRSLTKRSLTAAHEHHGRL 459
YT WAV I G A+ +A +GF+N+G+I D+YHF+H KRS+ ++ H +
Sbjct: 21 YTNHWAVKIAGGFPEANRIASKYGFINIGQIGALKDYYHFYHSRTIKRSVISSRGTHSFI 80
Query: 460 EGDSRVRWAEQQKILSRKKRDF 525
+ +V W +QQ + R KRD+
Sbjct: 81 SMEPKVEWIQQQVVKKRTKRDY 102
Score = 31.1 bits (67), Expect = 4.2
Identities = 9/12 (75%), Positives = 11/12 (91%)
Frame = +1
Query: 676 NDPKWPHMWYLN 711
NDPKWP MWY++
Sbjct: 113 NDPKWPSMWYMH 124
>BC012064-1|AAH12064.1| 913|Homo sapiens proprotein convertase
subtilisin/kexin type 5 protein.
Length = 913
Score = 68.5 bits (160), Expect = 2e-11
Identities = 31/82 (37%), Positives = 48/82 (58%), Gaps = 2/82 (2%)
Frame = +1
Query: 286 YTPTWAVHIPEGREVADAVARDHGFVNLGKI--FDDHYHFHHRSLTKRSLTAAHEHHGRL 459
YT WAV I G A+ +A +GF+N+G+I D+YHF+H KRS+ ++ H +
Sbjct: 35 YTNHWAVKIAGGFPEANRIASKYGFINIGQIGALKDYYHFYHSRTIKRSVISSRGTHSFI 94
Query: 460 EGDSRVRWAEQQKILSRKKRDF 525
+ +V W +QQ + R KRD+
Sbjct: 95 SMEPKVEWIQQQVVKKRTKRDY 116
Score = 31.1 bits (67), Expect = 4.2
Identities = 9/12 (75%), Positives = 11/12 (91%)
Frame = +1
Query: 676 NDPKWPHMWYLN 711
NDPKWP MWY++
Sbjct: 127 NDPKWPSMWYMH 138
>AL359253-2|CAH73743.1| 913|Homo sapiens proprotein convertase
subtilisin/kexin type 5 protein.
Length = 913
Score = 68.5 bits (160), Expect = 2e-11
Identities = 31/82 (37%), Positives = 48/82 (58%), Gaps = 2/82 (2%)
Frame = +1
Query: 286 YTPTWAVHIPEGREVADAVARDHGFVNLGKI--FDDHYHFHHRSLTKRSLTAAHEHHGRL 459
YT WAV I G A+ +A +GF+N+G+I D+YHF+H KRS+ ++ H +
Sbjct: 35 YTNHWAVKIAGGFPEANRIASKYGFINIGQIGALKDYYHFYHSRTIKRSVISSRGTHSFI 94
Query: 460 EGDSRVRWAEQQKILSRKKRDF 525
+ +V W +QQ + R KRD+
Sbjct: 95 SMEPKVEWIQQQVVKKRTKRDY 116
Score = 31.1 bits (67), Expect = 4.2
Identities = 9/12 (75%), Positives = 11/12 (91%)
Frame = +1
Query: 676 NDPKWPHMWYLN 711
NDPKWP MWY++
Sbjct: 127 NDPKWPSMWYMH 138
>AL359253-1|CAH73742.1| 690|Homo sapiens proprotein convertase
subtilisin/kexin type 5 protein.
Length = 690
Score = 68.5 bits (160), Expect = 2e-11
Identities = 31/82 (37%), Positives = 48/82 (58%), Gaps = 2/82 (2%)
Frame = +1
Query: 286 YTPTWAVHIPEGREVADAVARDHGFVNLGKI--FDDHYHFHHRSLTKRSLTAAHEHHGRL 459
YT WAV I G A+ +A +GF+N+G+I D+YHF+H KRS+ ++ H +
Sbjct: 35 YTNHWAVKIAGGFPEANRIASKYGFINIGQIGALKDYYHFYHSRTIKRSVISSRGTHSFI 94
Query: 460 EGDSRVRWAEQQKILSRKKRDF 525
+ +V W +QQ + R KRD+
Sbjct: 95 SMEPKVEWIQQQVVKKRTKRDY 116
Score = 31.1 bits (67), Expect = 4.2
Identities = 9/12 (75%), Positives = 11/12 (91%)
Frame = +1
Query: 676 NDPKWPHMWYLN 711
NDPKWP MWY++
Sbjct: 127 NDPKWPSMWYMH 138
>AL353607-2|CAI41233.1| 913|Homo sapiens proprotein convertase
subtilisin/kexin type 5 protein.
Length = 913
Score = 68.5 bits (160), Expect = 2e-11
Identities = 31/82 (37%), Positives = 48/82 (58%), Gaps = 2/82 (2%)
Frame = +1
Query: 286 YTPTWAVHIPEGREVADAVARDHGFVNLGKI--FDDHYHFHHRSLTKRSLTAAHEHHGRL 459
YT WAV I G A+ +A +GF+N+G+I D+YHF+H KRS+ ++ H +
Sbjct: 35 YTNHWAVKIAGGFPEANRIASKYGFINIGQIGALKDYYHFYHSRTIKRSVISSRGTHSFI 94
Query: 460 EGDSRVRWAEQQKILSRKKRDF 525
+ +V W +QQ + R KRD+
Sbjct: 95 SMEPKVEWIQQQVVKKRTKRDY 116
Score = 31.1 bits (67), Expect = 4.2
Identities = 9/12 (75%), Positives = 11/12 (91%)
Frame = +1
Query: 676 NDPKWPHMWYLN 711
NDPKWP MWY++
Sbjct: 127 NDPKWPSMWYMH 138
>AL353607-1|CAI41232.1| 690|Homo sapiens proprotein convertase
subtilisin/kexin type 5 protein.
Length = 690
Score = 68.5 bits (160), Expect = 2e-11
Identities = 31/82 (37%), Positives = 48/82 (58%), Gaps = 2/82 (2%)
Frame = +1
Query: 286 YTPTWAVHIPEGREVADAVARDHGFVNLGKI--FDDHYHFHHRSLTKRSLTAAHEHHGRL 459
YT WAV I G A+ +A +GF+N+G+I D+YHF+H KRS+ ++ H +
Sbjct: 35 YTNHWAVKIAGGFPEANRIASKYGFINIGQIGALKDYYHFYHSRTIKRSVISSRGTHSFI 94
Query: 460 EGDSRVRWAEQQKILSRKKRDF 525
+ +V W +QQ + R KRD+
Sbjct: 95 SMEPKVEWIQQQVVKKRTKRDY 116
Score = 31.1 bits (67), Expect = 4.2
Identities = 9/12 (75%), Positives = 11/12 (91%)
Frame = +1
Query: 676 NDPKWPHMWYLN 711
NDPKWP MWY++
Sbjct: 127 NDPKWPSMWYMH 138
>AY358963-1|AAQ89322.1| 755|Homo sapiens prohormone convertase
protein.
Length = 755
Score = 67.7 bits (158), Expect = 4e-11
Identities = 31/80 (38%), Positives = 47/80 (58%), Gaps = 2/80 (2%)
Frame = +1
Query: 286 YTPTWAVHIPEGREVADAVARDHGFVNLGKIFDD--HYHFHHRSLTKRSLTAAHEHHGRL 459
Y +WAV + +G + +AR GFVNLG IF D ++H HR + ++SLT H L
Sbjct: 34 YVSSWAVQVSQGNREVERLARKFGFVNLGPIFSDGQYFHLRHRGVVQQSLTPHWGHRLHL 93
Query: 460 EGDSRVRWAEQQKILSRKKR 519
+ + +V+W +QQ + R KR
Sbjct: 94 KKNPKVQWFQQQTLQRRVKR 113
>X64810-1|CAA46031.1| 753|Homo sapiens PC1/PC3 protein.
Length = 753
Score = 61.3 bits (142), Expect(2) = 1e-10
Identities = 33/76 (43%), Positives = 43/76 (56%), Gaps = 2/76 (2%)
Frame = +1
Query: 298 WAVHIPEGREVADAVARDHGFVNLGKI--FDDHYHFHHRSLTKRSLTAAHEHHGRLEGDS 471
WA IP G E A A+A + G+ LG+I ++HY F H++ +RS +A RL D
Sbjct: 35 WAAEIPGGPEAASAIAEELGYDLLGQIGSLENHYLFKHKNHPRRSRRSAFHITKRLSDDD 94
Query: 472 RVRWAEQQKILSRKKR 519
RV WAEQQ R KR
Sbjct: 95 RVIWAEQQYEKERSKR 110
Score = 25.0 bits (52), Expect(2) = 1e-10
Identities = 10/24 (41%), Positives = 12/24 (50%)
Frame = +1
Query: 637 RGXTRSADLKFILNDPKWPHMWYL 708
R R + L + NDP W WYL
Sbjct: 110 RSALRDSALN-LFNDPMWNQQWYL 132
>M90753-1|AAA59918.1| 753|Homo sapiens PC1 protein.
Length = 753
Score = 61.3 bits (142), Expect(2) = 1e-10
Identities = 33/76 (43%), Positives = 43/76 (56%), Gaps = 2/76 (2%)
Frame = +1
Query: 298 WAVHIPEGREVADAVARDHGFVNLGKI--FDDHYHFHHRSLTKRSLTAAHEHHGRLEGDS 471
WA IP G E A A+A + G+ LG+I ++HY F H++ +RS +A RL D
Sbjct: 35 WAAEIPGGPEAASAIAEELGYDLLGQIGSLENHYLFKHKNHPRRSRRSAFHITKRLSDDD 94
Query: 472 RVRWAEQQKILSRKKR 519
RV WAEQQ R KR
Sbjct: 95 RVIWAEQQYEKERSKR 110
Score = 25.0 bits (52), Expect(2) = 1e-10
Identities = 10/24 (41%), Positives = 12/24 (50%)
Frame = +1
Query: 637 RGXTRSADLKFILNDPKWPHMWYL 708
R R + L + NDP W WYL
Sbjct: 110 RSALRDSALN-LFNDPMWNQQWYL 132
>D73407-1|BAA11133.1| 753|Homo sapiens prohormone convertase 3
protein.
Length = 753
Score = 61.3 bits (142), Expect(2) = 1e-10
Identities = 33/76 (43%), Positives = 43/76 (56%), Gaps = 2/76 (2%)
Frame = +1
Query: 298 WAVHIPEGREVADAVARDHGFVNLGKI--FDDHYHFHHRSLTKRSLTAAHEHHGRLEGDS 471
WA IP G E A A+A + G+ LG+I ++HY F H++ +RS +A RL D
Sbjct: 35 WAAEIPGGPEAASAIAEELGYDLLGQIGSLENHYLFKHKNHPRRSRRSAFHITKRLSDDD 94
Query: 472 RVRWAEQQKILSRKKR 519
RV WAEQQ R KR
Sbjct: 95 RVIWAEQQYEKERSKR 110
Score = 25.0 bits (52), Expect(2) = 1e-10
Identities = 10/24 (41%), Positives = 12/24 (50%)
Frame = +1
Query: 637 RGXTRSADLKFILNDPKWPHMWYL 708
R R + L + NDP W WYL
Sbjct: 110 RSALRDSALN-LFNDPMWNQQWYL 132
>BC130295-1|AAI30296.1| 753|Homo sapiens proprotein convertase
subtilisin/kexin type 1 protein.
Length = 753
Score = 61.3 bits (142), Expect(2) = 1e-10
Identities = 33/76 (43%), Positives = 43/76 (56%), Gaps = 2/76 (2%)
Frame = +1
Query: 298 WAVHIPEGREVADAVARDHGFVNLGKI--FDDHYHFHHRSLTKRSLTAAHEHHGRLEGDS 471
WA IP G E A A+A + G+ LG+I ++HY F H++ +RS +A RL D
Sbjct: 35 WAAEIPGGPEAASAIAEELGYDLLGQIGSLENHYLFKHKNHPRRSRRSAFHITKRLSDDD 94
Query: 472 RVRWAEQQKILSRKKR 519
RV WAEQQ R KR
Sbjct: 95 RVIWAEQQYEKERSKR 110
Score = 25.0 bits (52), Expect(2) = 1e-10
Identities = 10/24 (41%), Positives = 12/24 (50%)
Frame = +1
Query: 637 RGXTRSADLKFILNDPKWPHMWYL 708
R R + L + NDP W WYL
Sbjct: 110 RSALRDSALN-LFNDPMWNQQWYL 132
>AB208874-1|BAD92111.1| 724|Homo sapiens proprotein convertase
subtilisin/kexin type 1 preproprotein variant protein.
Length = 724
Score = 61.3 bits (142), Expect(2) = 1e-10
Identities = 33/76 (43%), Positives = 43/76 (56%), Gaps = 2/76 (2%)
Frame = +1
Query: 298 WAVHIPEGREVADAVARDHGFVNLGKI--FDDHYHFHHRSLTKRSLTAAHEHHGRLEGDS 471
WA IP G E A A+A + G+ LG+I ++HY F H++ +RS +A RL D
Sbjct: 6 WAAEIPGGPEAASAIAEELGYDLLGQIGSLENHYLFKHKNHPRRSRRSAFHITKRLSDDD 65
Query: 472 RVRWAEQQKILSRKKR 519
RV WAEQQ R KR
Sbjct: 66 RVIWAEQQYEKERSKR 81
Score = 25.0 bits (52), Expect(2) = 1e-10
Identities = 10/24 (41%), Positives = 12/24 (50%)
Frame = +1
Query: 637 RGXTRSADLKFILNDPKWPHMWYL 708
R R + L + NDP W WYL
Sbjct: 81 RSALRDSALN-LFNDPMWNQQWYL 103
>AM491522-1|CAM33226.1| 357|Homo sapiens proprotein convertase
subtilisin/kexin type 6 protein.
Length = 357
Score = 60.5 bits (140), Expect = 6e-09
Identities = 29/69 (42%), Positives = 42/69 (60%), Gaps = 2/69 (2%)
Frame = +1
Query: 319 GREVADAVARDHGFVNLGKI--FDDHYHFHHRSLTKRSLTAAHEHHGRLEGDSRVRWAEQ 492
G AD VA HG++NLG+I +D+YHF+H KRS ++ H L D +V+W +Q
Sbjct: 2 GPAEADRVAAAHGYLNLGQIGNLEDYYHFYHSKTFKRSTLSSRGPHTFLRMDPQVKWLQQ 61
Query: 493 QKILSRKKR 519
Q++ R KR
Sbjct: 62 QEVKRRVKR 70
Score = 31.5 bits (68), Expect = 3.2
Identities = 12/35 (34%), Positives = 19/35 (54%)
Frame = +1
Query: 613 KRXLNTRIRGXTRSADLKFILNDPKWPHMWYLNRG 717
++ + R++ RS NDP W +MWYL+ G
Sbjct: 61 QQEVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCG 95
>M95971-1|AAA59919.1| 638|Homo sapiens neuroendocrine convertase 2
protein.
Length = 638
Score = 49.6 bits (113), Expect(2) = 2e-06
Identities = 28/76 (36%), Positives = 40/76 (52%), Gaps = 1/76 (1%)
Frame = +1
Query: 319 GREVADAVARDHGF-VNLGKIFDDHYHFHHRSLTKRSLTAAHEHHGRLEGDSRVRWAEQQ 495
G + A VA +HGF V + YHF+H L K + H +LE D RV+ A QQ
Sbjct: 42 GEDKARQVAAEHGFGVRKLPFAEGLYHFYHNGLAKAKRRRSLHHKQQLERDPRVKMALQQ 101
Query: 496 KILSRKKRDFQIISTL 543
+ RKKR ++ I+ +
Sbjct: 102 EGFDRKKRGYRDINEI 117
Score = 21.8 bits (44), Expect(2) = 2e-06
Identities = 9/28 (32%), Positives = 13/28 (46%)
Frame = +1
Query: 637 RGXTRSADLKFILNDPKWPHMWYLNRGG 720
RG ++ +NDP + WYL G
Sbjct: 109 RGYRDINEIDINMNDPLFTKQWYLINTG 136
>J05252-1|AAA60032.1| 638|Homo sapiens endoprotease protein.
Length = 638
Score = 49.6 bits (113), Expect(2) = 2e-06
Identities = 28/76 (36%), Positives = 40/76 (52%), Gaps = 1/76 (1%)
Frame = +1
Query: 319 GREVADAVARDHGF-VNLGKIFDDHYHFHHRSLTKRSLTAAHEHHGRLEGDSRVRWAEQQ 495
G + A VA +HGF V + YHF+H L K + H +LE D RV+ A QQ
Sbjct: 42 GEDKARQVAAEHGFGVRKLPFAEGLYHFYHNGLAKAKRRRSLHHKQQLERDPRVKMALQQ 101
Query: 496 KILSRKKRDFQIISTL 543
+ RKKR ++ I+ +
Sbjct: 102 EGFDRKKRGYRDINEI 117
Score = 21.8 bits (44), Expect(2) = 2e-06
Identities = 9/28 (32%), Positives = 13/28 (46%)
Frame = +1
Query: 637 RGXTRSADLKFILNDPKWPHMWYLNRGG 720
RG ++ +NDP + WYL G
Sbjct: 109 RGYRDINEIDINMNDPLFTKQWYLINTG 136
>BC005815-1|AAH05815.1| 638|Homo sapiens proprotein convertase
subtilisin/kexin type 2 protein.
Length = 638
Score = 49.6 bits (113), Expect(2) = 2e-06
Identities = 28/76 (36%), Positives = 40/76 (52%), Gaps = 1/76 (1%)
Frame = +1
Query: 319 GREVADAVARDHGF-VNLGKIFDDHYHFHHRSLTKRSLTAAHEHHGRLEGDSRVRWAEQQ 495
G + A VA +HGF V + YHF+H L K + H +LE D RV+ A QQ
Sbjct: 42 GEDKARQVAAEHGFGVRKLPFAEGLYHFYHNGLAKAKRRRSLHHKQQLERDPRVKMALQQ 101
Query: 496 KILSRKKRDFQIISTL 543
+ RKKR ++ I+ +
Sbjct: 102 EGFDRKKRGYRDINEI 117
Score = 21.8 bits (44), Expect(2) = 2e-06
Identities = 9/28 (32%), Positives = 13/28 (46%)
Frame = +1
Query: 637 RGXTRSADLKFILNDPKWPHMWYLNRGG 720
RG ++ +NDP + WYL G
Sbjct: 109 RGYRDINEIDINMNDPLFTKQWYLINTG 136
>AL359511-2|CAI20085.1| 638|Homo sapiens proprotein convertase
subtilisin/kexin type 2 protein.
Length = 638
Score = 49.6 bits (113), Expect(2) = 2e-06
Identities = 28/76 (36%), Positives = 40/76 (52%), Gaps = 1/76 (1%)
Frame = +1
Query: 319 GREVADAVARDHGF-VNLGKIFDDHYHFHHRSLTKRSLTAAHEHHGRLEGDSRVRWAEQQ 495
G + A VA +HGF V + YHF+H L K + H +LE D RV+ A QQ
Sbjct: 42 GEDKARQVAAEHGFGVRKLPFAEGLYHFYHNGLAKAKRRRSLHHKQQLERDPRVKMALQQ 101
Query: 496 KILSRKKRDFQIISTL 543
+ RKKR ++ I+ +
Sbjct: 102 EGFDRKKRGYRDINEI 117
Score = 21.8 bits (44), Expect(2) = 2e-06
Identities = 9/28 (32%), Positives = 13/28 (46%)
Frame = +1
Query: 637 RGXTRSADLKFILNDPKWPHMWYLNRGG 720
RG ++ +NDP + WYL G
Sbjct: 109 RGYRDINEIDINMNDPLFTKQWYLINTG 136
>AL121779-1|CAI19155.1| 638|Homo sapiens proprotein convertase
subtilisin/kexin type 2 protein.
Length = 638
Score = 49.6 bits (113), Expect(2) = 2e-06
Identities = 28/76 (36%), Positives = 40/76 (52%), Gaps = 1/76 (1%)
Frame = +1
Query: 319 GREVADAVARDHGF-VNLGKIFDDHYHFHHRSLTKRSLTAAHEHHGRLEGDSRVRWAEQQ 495
G + A VA +HGF V + YHF+H L K + H +LE D RV+ A QQ
Sbjct: 42 GEDKARQVAAEHGFGVRKLPFAEGLYHFYHNGLAKAKRRRSLHHKQQLERDPRVKMALQQ 101
Query: 496 KILSRKKRDFQIISTL 543
+ RKKR ++ I+ +
Sbjct: 102 EGFDRKKRGYRDINEI 117
Score = 21.8 bits (44), Expect(2) = 2e-06
Identities = 9/28 (32%), Positives = 13/28 (46%)
Frame = +1
Query: 637 RGXTRSADLKFILNDPKWPHMWYLNRGG 720
RG ++ +NDP + WYL G
Sbjct: 109 RGYRDINEIDINMNDPLFTKQWYLINTG 136
>AL031675-1|CAI22648.1| 638|Homo sapiens proprotein convertase
subtilisin/kexin type 2 protein.
Length = 638
Score = 49.6 bits (113), Expect(2) = 2e-06
Identities = 28/76 (36%), Positives = 40/76 (52%), Gaps = 1/76 (1%)
Frame = +1
Query: 319 GREVADAVARDHGF-VNLGKIFDDHYHFHHRSLTKRSLTAAHEHHGRLEGDSRVRWAEQQ 495
G + A VA +HGF V + YHF+H L K + H +LE D RV+ A QQ
Sbjct: 42 GEDKARQVAAEHGFGVRKLPFAEGLYHFYHNGLAKAKRRRSLHHKQQLERDPRVKMALQQ 101
Query: 496 KILSRKKRDFQIISTL 543
+ RKKR ++ I+ +
Sbjct: 102 EGFDRKKRGYRDINEI 117
Score = 21.8 bits (44), Expect(2) = 2e-06
Identities = 9/28 (32%), Positives = 13/28 (46%)
Frame = +1
Query: 637 RGXTRSADLKFILNDPKWPHMWYLNRGG 720
RG ++ +NDP + WYL G
Sbjct: 109 RGYRDINEIDINMNDPLFTKQWYLINTG 136
>AL031664-2|CAI21690.1| 638|Homo sapiens proprotein convertase
subtilisin/kexin type 2 protein.
Length = 638
Score = 49.6 bits (113), Expect(2) = 2e-06
Identities = 28/76 (36%), Positives = 40/76 (52%), Gaps = 1/76 (1%)
Frame = +1
Query: 319 GREVADAVARDHGF-VNLGKIFDDHYHFHHRSLTKRSLTAAHEHHGRLEGDSRVRWAEQQ 495
G + A VA +HGF V + YHF+H L K + H +LE D RV+ A QQ
Sbjct: 42 GEDKARQVAAEHGFGVRKLPFAEGLYHFYHNGLAKAKRRRSLHHKQQLERDPRVKMALQQ 101
Query: 496 KILSRKKRDFQIISTL 543
+ RKKR ++ I+ +
Sbjct: 102 EGFDRKKRGYRDINEI 117
Score = 21.8 bits (44), Expect(2) = 2e-06
Identities = 9/28 (32%), Positives = 13/28 (46%)
Frame = +1
Query: 637 RGXTRSADLKFILNDPKWPHMWYLNRGG 720
RG ++ +NDP + WYL G
Sbjct: 109 RGYRDINEIDINMNDPLFTKQWYLINTG 136
>BC040546-1|AAH40546.1| 619|Homo sapiens PCSK2 protein protein.
Length = 619
Score = 49.6 bits (113), Expect(2) = 2e-06
Identities = 28/76 (36%), Positives = 40/76 (52%), Gaps = 1/76 (1%)
Frame = +1
Query: 319 GREVADAVARDHGF-VNLGKIFDDHYHFHHRSLTKRSLTAAHEHHGRLEGDSRVRWAEQQ 495
G + A VA +HGF V + YHF+H L K + H +LE D RV+ A QQ
Sbjct: 23 GEDKARQVAAEHGFGVRKLPFAEGLYHFYHNGLAKAKRRRSLHHKQQLERDPRVKMALQQ 82
Query: 496 KILSRKKRDFQIISTL 543
+ RKKR ++ I+ +
Sbjct: 83 EGFDRKKRGYRDINEI 98
Score = 21.8 bits (44), Expect(2) = 2e-06
Identities = 9/28 (32%), Positives = 13/28 (46%)
Frame = +1
Query: 637 RGXTRSADLKFILNDPKWPHMWYLNRGG 720
RG ++ +NDP + WYL G
Sbjct: 90 RGYRDINEIDINMNDPLFTKQWYLINTG 117
>AL359511-3|CAC34957.2| 619|Homo sapiens proprotein convertase
subtilisin/kexin type 2 protein.
Length = 619
Score = 49.6 bits (113), Expect(2) = 2e-06
Identities = 28/76 (36%), Positives = 40/76 (52%), Gaps = 1/76 (1%)
Frame = +1
Query: 319 GREVADAVARDHGF-VNLGKIFDDHYHFHHRSLTKRSLTAAHEHHGRLEGDSRVRWAEQQ 495
G + A VA +HGF V + YHF+H L K + H +LE D RV+ A QQ
Sbjct: 23 GEDKARQVAAEHGFGVRKLPFAEGLYHFYHNGLAKAKRRRSLHHKQQLERDPRVKMALQQ 82
Query: 496 KILSRKKRDFQIISTL 543
+ RKKR ++ I+ +
Sbjct: 83 EGFDRKKRGYRDINEI 98
Score = 21.8 bits (44), Expect(2) = 2e-06
Identities = 9/28 (32%), Positives = 13/28 (46%)
Frame = +1
Query: 637 RGXTRSADLKFILNDPKWPHMWYLNRGG 720
RG ++ +NDP + WYL G
Sbjct: 90 RGYRDINEIDINMNDPLFTKQWYLINTG 117
>AL121779-2|CAB96732.2| 619|Homo sapiens proprotein convertase
subtilisin/kexin type 2 protein.
Length = 619
Score = 49.6 bits (113), Expect(2) = 2e-06
Identities = 28/76 (36%), Positives = 40/76 (52%), Gaps = 1/76 (1%)
Frame = +1
Query: 319 GREVADAVARDHGF-VNLGKIFDDHYHFHHRSLTKRSLTAAHEHHGRLEGDSRVRWAEQQ 495
G + A VA +HGF V + YHF+H L K + H +LE D RV+ A QQ
Sbjct: 23 GEDKARQVAAEHGFGVRKLPFAEGLYHFYHNGLAKAKRRRSLHHKQQLERDPRVKMALQQ 82
Query: 496 KILSRKKRDFQIISTL 543
+ RKKR ++ I+ +
Sbjct: 83 EGFDRKKRGYRDINEI 98
Score = 21.8 bits (44), Expect(2) = 2e-06
Identities = 9/28 (32%), Positives = 13/28 (46%)
Frame = +1
Query: 637 RGXTRSADLKFILNDPKWPHMWYLNRGG 720
RG ++ +NDP + WYL G
Sbjct: 90 RGYRDINEIDINMNDPLFTKQWYLINTG 117
>AL031675-2|CAA21069.2| 619|Homo sapiens proprotein convertase
subtilisin/kexin type 2 protein.
Length = 619
Score = 49.6 bits (113), Expect(2) = 2e-06
Identities = 28/76 (36%), Positives = 40/76 (52%), Gaps = 1/76 (1%)
Frame = +1
Query: 319 GREVADAVARDHGF-VNLGKIFDDHYHFHHRSLTKRSLTAAHEHHGRLEGDSRVRWAEQQ 495
G + A VA +HGF V + YHF+H L K + H +LE D RV+ A QQ
Sbjct: 23 GEDKARQVAAEHGFGVRKLPFAEGLYHFYHNGLAKAKRRRSLHHKQQLERDPRVKMALQQ 82
Query: 496 KILSRKKRDFQIISTL 543
+ RKKR ++ I+ +
Sbjct: 83 EGFDRKKRGYRDINEI 98
Score = 21.8 bits (44), Expect(2) = 2e-06
Identities = 9/28 (32%), Positives = 13/28 (46%)
Frame = +1
Query: 637 RGXTRSADLKFILNDPKWPHMWYLNRGG 720
RG ++ +NDP + WYL G
Sbjct: 90 RGYRDINEIDINMNDPLFTKQWYLINTG 117
>AL031664-3|CAB89428.2| 619|Homo sapiens proprotein convertase
subtilisin/kexin type 2 protein.
Length = 619
Score = 49.6 bits (113), Expect(2) = 2e-06
Identities = 28/76 (36%), Positives = 40/76 (52%), Gaps = 1/76 (1%)
Frame = +1
Query: 319 GREVADAVARDHGF-VNLGKIFDDHYHFHHRSLTKRSLTAAHEHHGRLEGDSRVRWAEQQ 495
G + A VA +HGF V + YHF+H L K + H +LE D RV+ A QQ
Sbjct: 23 GEDKARQVAAEHGFGVRKLPFAEGLYHFYHNGLAKAKRRRSLHHKQQLERDPRVKMALQQ 82
Query: 496 KILSRKKRDFQIISTL 543
+ RKKR ++ I+ +
Sbjct: 83 EGFDRKKRGYRDINEI 98
Score = 21.8 bits (44), Expect(2) = 2e-06
Identities = 9/28 (32%), Positives = 13/28 (46%)
Frame = +1
Query: 637 RGXTRSADLKFILNDPKWPHMWYLNRGG 720
RG ++ +NDP + WYL G
Sbjct: 90 RGYRDINEIDINMNDPLFTKQWYLINTG 117
>AB208955-1|BAD92192.1| 800|Homo sapiens paired basic amino acid
cleaving system 4 isoform a preproprotein variant
protein.
Length = 800
Score = 47.2 bits (107), Expect = 6e-05
Identities = 22/54 (40%), Positives = 33/54 (61%), Gaps = 2/54 (3%)
Frame = +1
Query: 364 NLGKI--FDDHYHFHHRSLTKRSLTAAHEHHGRLEGDSRVRWAEQQKILSRKKR 519
NLG+I +D+YHF+H KRS ++ H L D +V+W +QQ++ R KR
Sbjct: 1 NLGQIGNLEDYYHFYHSKTFKRSTLSSRGPHTFLRMDPQVKWLQQQEVKRRVKR 54
Score = 31.5 bits (68), Expect = 3.2
Identities = 12/35 (34%), Positives = 19/35 (54%)
Frame = +1
Query: 613 KRXLNTRIRGXTRSADLKFILNDPKWPHMWYLNRG 717
++ + R++ RS NDP W +MWYL+ G
Sbjct: 45 QQEVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCG 79
>BT006870-1|AAP35516.1| 785|Homo sapiens proprotein convertase
subtilisin/kexin type 7 protein.
Length = 785
Score = 38.7 bits (86), Expect = 0.021
Identities = 32/92 (34%), Positives = 44/92 (47%), Gaps = 16/92 (17%)
Frame = +1
Query: 292 PTWAVHIP----EGREV-----ADAVARDHGFVNLGKI--FDDHYHF-----HHRSLTKR 423
P+WAVH+ +G E ADA+A+ G VN G+I HY F H +L
Sbjct: 52 PSWAVHLESLEGDGEEETLEQQADALAQAAGLVNAGRIGELQGHYLFVQPAGHRPALEVE 111
Query: 424 SLTAAHEHHGRLEGDSRVRWAEQQKILSRKKR 519
++ E L G VRW +Q++L R KR
Sbjct: 112 AIRQQVE--AVLAGHEAVRWHSEQRLLRRAKR 141
>BC010696-1|AAH10696.1| 785|Homo sapiens proprotein convertase
subtilisin/kexin type 7 protein.
Length = 785
Score = 38.7 bits (86), Expect = 0.021
Identities = 32/92 (34%), Positives = 44/92 (47%), Gaps = 16/92 (17%)
Frame = +1
Query: 292 PTWAVHIP----EGREV-----ADAVARDHGFVNLGKI--FDDHYHF-----HHRSLTKR 423
P+WAVH+ +G E ADA+A+ G VN G+I HY F H +L
Sbjct: 52 PSWAVHLESLEGDGEEETLEQQADALAQAAGLVNAGRIGELQGHYLFVQPAGHRPALEVE 111
Query: 424 SLTAAHEHHGRLEGDSRVRWAEQQKILSRKKR 519
++ E L G VRW +Q++L R KR
Sbjct: 112 AIRQQVE--AVLAGHEAVRWHSEQRLLRRAKR 141
>BC006357-1|AAH06357.1| 591|Homo sapiens PCSK7 protein protein.
Length = 591
Score = 38.7 bits (86), Expect = 0.021
Identities = 32/92 (34%), Positives = 44/92 (47%), Gaps = 16/92 (17%)
Frame = +1
Query: 292 PTWAVHIP----EGREV-----ADAVARDHGFVNLGKI--FDDHYHF-----HHRSLTKR 423
P+WAVH+ +G E ADA+A+ G VN G+I HY F H +L
Sbjct: 52 PSWAVHLESLEGDGEEETLEQQADALAQAAGLVNAGRIGELQGHYLFVQPAGHRPALEVE 111
Query: 424 SLTAAHEHHGRLEGDSRVRWAEQQKILSRKKR 519
++ E L G VRW +Q++L R KR
Sbjct: 112 AIRQQVE--AVLAGHEAVRWHSEQRLLRRAKR 141
>AK222907-1|BAD96627.1| 785|Homo sapiens proprotein convertase
subtilisin/kexin type 7 preproprotein variant protein.
Length = 785
Score = 38.7 bits (86), Expect = 0.021
Identities = 32/92 (34%), Positives = 44/92 (47%), Gaps = 16/92 (17%)
Frame = +1
Query: 292 PTWAVHIP----EGREV-----ADAVARDHGFVNLGKI--FDDHYHF-----HHRSLTKR 423
P+WAVH+ +G E ADA+A+ G VN G+I HY F H +L
Sbjct: 52 PSWAVHLESLEGDGEEETLEQQADALAQAAGLVNAGRIGELQGHYLFVQPAGHRPALEVE 111
Query: 424 SLTAAHEHHGRLEGDSRVRWAEQQKILSRKKR 519
++ E L G VRW +Q++L R KR
Sbjct: 112 AIRQQVE--AVLAGHEAVRWHSEQRLLRRAKR 141
>U40623-1|AAC50417.1| 785|Homo sapiens PC8 precursor protein.
Length = 785
Score = 35.5 bits (78), Expect = 0.19
Identities = 29/89 (32%), Positives = 42/89 (47%), Gaps = 14/89 (15%)
Frame = +1
Query: 295 TWAVHIP----EGREV-----ADAVARDHGFVNLGKI--FDDHYHFHHRSLTKRSLTA-- 435
+WAVH+ +G E ADA+A+ G VN G+I HY F + + +L
Sbjct: 53 SWAVHLESLEGDGEEETLEQQADALAQAAGLVNAGRIGELQGHYLFVQPAGHRPALEVEP 112
Query: 436 -AHEHHGRLEGDSRVRWAEQQKILSRKKR 519
+ L G VRW +Q++L R KR
Sbjct: 113 IRQQVEAVLAGHEAVRWHSEQRLLRRAKR 141
>U33849-1|AAB03087.1| 785|Homo sapiens lymphoma proprotein
convertase protein.
Length = 785
Score = 35.5 bits (78), Expect = 0.19
Identities = 29/89 (32%), Positives = 42/89 (47%), Gaps = 14/89 (15%)
Frame = +1
Query: 295 TWAVHIP----EGREV-----ADAVARDHGFVNLGKI--FDDHYHFHHRSLTKRSLTA-- 435
+WAVH+ +G E ADA+A+ G VN G+I HY F + + +L
Sbjct: 53 SWAVHLESLEGDGEEETLEQQADALAQAAGLVNAGRIGELQGHYLFVQPAGHRPALEVEP 112
Query: 436 -AHEHHGRLEGDSRVRWAEQQKILSRKKR 519
+ L G VRW +Q++L R KR
Sbjct: 113 IRQQVEAVLAGHEAVRWHSEQRLLRRAKR 141
>D29677-1|BAA06147.2| 1943|Homo sapiens KIAA0054 protein.
Length = 1943
Score = 30.3 bits (65), Expect = 7.3
Identities = 17/55 (30%), Positives = 25/55 (45%), Gaps = 5/55 (9%)
Frame = +1
Query: 313 PEGREVADAVARDHGFVNLGKIFDDHYHF-----HHRSLTKRSLTAAHEHHGRLE 462
P G + +A+ R HG V L + F HH L++ S+ H HH L+
Sbjct: 1488 PSGLPIGEALDRIHGSVALETLRQQQARFQQWSEHHAFLSQGSVPYPHHHHPHLQ 1542
>BC130582-1|AAI30583.1| 1942|Homo sapiens helicase with zinc finger
protein.
Length = 1942
Score = 30.3 bits (65), Expect = 7.3
Identities = 17/55 (30%), Positives = 25/55 (45%), Gaps = 5/55 (9%)
Frame = +1
Query: 313 PEGREVADAVARDHGFVNLGKIFDDHYHF-----HHRSLTKRSLTAAHEHHGRLE 462
P G + +A+ R HG V L + F HH L++ S+ H HH L+
Sbjct: 1487 PSGLPIGEALDRIHGSVALETLRQQQARFQQWSEHHAFLSQGSVPYPHHHHPHLQ 1541
>Y00508-1|CAA68560.1| 460|Homo sapiens muscarinic acetylcholine
receptor protein.
Length = 460
Score = 29.9 bits (64), Expect = 9.6
Identities = 19/47 (40%), Positives = 24/47 (51%), Gaps = 2/47 (4%)
Frame = +3
Query: 243 PGVGSVAH*NNTRALHANMGRPYTGRKRSCRCRRQGPRLRQ--SWKD 377
PG G + ++ R+ G P T R CRC R PRL Q SWK+
Sbjct: 231 PGKGGGSSSSSERSQPGAEGSPETPPGRCCRCCR-APRLLQAYSWKE 276
>X52068-1|CAA36291.1| 460|Homo sapiens protein ( Human gene for M1
muscarinic acetylcholine receptor. ).
Length = 460
Score = 29.9 bits (64), Expect = 9.6
Identities = 19/47 (40%), Positives = 24/47 (51%), Gaps = 2/47 (4%)
Frame = +3
Query: 243 PGVGSVAH*NNTRALHANMGRPYTGRKRSCRCRRQGPRLRQ--SWKD 377
PG G + ++ R+ G P T R CRC R PRL Q SWK+
Sbjct: 231 PGKGGGSSSSSERSQPGAEGSPETPPGRCCRCCR-APRLLQAYSWKE 276
>X15263-1|CAA33334.1| 460|Homo sapiens protein ( Human gene for
muscarinic acetylcholine receptor HM1. ).
Length = 460
Score = 29.9 bits (64), Expect = 9.6
Identities = 19/47 (40%), Positives = 24/47 (51%), Gaps = 2/47 (4%)
Frame = +3
Query: 243 PGVGSVAH*NNTRALHANMGRPYTGRKRSCRCRRQGPRLRQ--SWKD 377
PG G + ++ R+ G P T R CRC R PRL Q SWK+
Sbjct: 231 PGKGGGSSSSSERSQPGAEGSPETPPGRCCRCCR-APRLLQAYSWKE 276
>BT007166-1|AAP35830.1| 460|Homo sapiens cholinergic receptor,
muscarinic 1 protein.
Length = 460
Score = 29.9 bits (64), Expect = 9.6
Identities = 19/47 (40%), Positives = 24/47 (51%), Gaps = 2/47 (4%)
Frame = +3
Query: 243 PGVGSVAH*NNTRALHANMGRPYTGRKRSCRCRRQGPRLRQ--SWKD 377
PG G + ++ R+ G P T R CRC R PRL Q SWK+
Sbjct: 231 PGKGGGSSSSSERSQPGAEGSPETPPGRCCRCCR-APRLLQAYSWKE 276
>BC022984-1|AAH22984.1| 460|Homo sapiens cholinergic receptor,
muscarinic 1 protein.
Length = 460
Score = 29.9 bits (64), Expect = 9.6
Identities = 19/47 (40%), Positives = 24/47 (51%), Gaps = 2/47 (4%)
Frame = +3
Query: 243 PGVGSVAH*NNTRALHANMGRPYTGRKRSCRCRRQGPRLRQ--SWKD 377
PG G + ++ R+ G P T R CRC R PRL Q SWK+
Sbjct: 231 PGKGGGSSSSSERSQPGAEGSPETPPGRCCRCCR-APRLLQAYSWKE 276
>BC007740-1|AAH07740.1| 460|Homo sapiens cholinergic receptor,
muscarinic 1 protein.
Length = 460
Score = 29.9 bits (64), Expect = 9.6
Identities = 19/47 (40%), Positives = 24/47 (51%), Gaps = 2/47 (4%)
Frame = +3
Query: 243 PGVGSVAH*NNTRALHANMGRPYTGRKRSCRCRRQGPRLRQ--SWKD 377
PG G + ++ R+ G P T R CRC R PRL Q SWK+
Sbjct: 231 PGKGGGSSSSSERSQPGAEGSPETPPGRCCRCCR-APRLLQAYSWKE 276
>AF498915-1|AAM18938.1| 460|Homo sapiens muscarinic acetylcholine
receptor M1 protein.
Length = 460
Score = 29.9 bits (64), Expect = 9.6
Identities = 19/47 (40%), Positives = 24/47 (51%), Gaps = 2/47 (4%)
Frame = +3
Query: 243 PGVGSVAH*NNTRALHANMGRPYTGRKRSCRCRRQGPRLRQ--SWKD 377
PG G + ++ R+ G P T R CRC R PRL Q SWK+
Sbjct: 231 PGKGGGSSSSSERSQPGAEGSPETPPGRCCRCCR-APRLLQAYSWKE 276
>AF385587-1|AAK68112.1| 454|Homo sapiens m1 muscarinic cholinergic
receptor protein.
Length = 454
Score = 29.9 bits (64), Expect = 9.6
Identities = 19/47 (40%), Positives = 24/47 (51%), Gaps = 2/47 (4%)
Frame = +3
Query: 243 PGVGSVAH*NNTRALHANMGRPYTGRKRSCRCRRQGPRLRQ--SWKD 377
PG G + ++ R+ G P T R CRC R PRL Q SWK+
Sbjct: 231 PGKGGGSSSSSERSQPGAEGSPETPPGRCCRCCR-APRLLQAYSWKE 276
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 103,664,454
Number of Sequences: 237096
Number of extensions: 2181123
Number of successful extensions: 4716
Number of sequences better than 10.0: 58
Number of HSP's better than 10.0 without gapping: 4493
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4691
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8511181328
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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