Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P12_F_B22
(588 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_UPI00015B60D2 Cluster: PREDICTED: similar to ENSANGP000... 236 3e-61
UniRef50_Q9VC92 Cluster: CG6432-PA; n=7; cellular organisms|Rep:... 219 3e-56
UniRef50_A7RH51 Cluster: Predicted protein; n=1; Nematostella ve... 193 3e-48
UniRef50_UPI0000E4931E Cluster: PREDICTED: hypothetical protein,... 188 1e-46
UniRef50_Q9H6R3 Cluster: CDNA: FLJ21963 fis, clone HEP05583; n=3... 188 1e-46
UniRef50_O67872 Cluster: Acetyl-coenzyme A synthetase; n=5; cell... 159 4e-38
UniRef50_P28812 Cluster: Uncharacterized protein PA3568; n=81; c... 153 4e-36
UniRef50_Q82EL5 Cluster: Acetyl-coenzyme A synthetase; n=28; cel... 150 3e-35
UniRef50_A5UUT7 Cluster: Acetate--CoA ligase; n=2; Roseiflexus|R... 149 5e-35
UniRef50_Q55404 Cluster: Acetyl-coenzyme A synthetase; n=89; cel... 149 5e-35
UniRef50_P55912 Cluster: Propionate--CoA ligase; n=57; Bacteria|... 149 6e-35
UniRef50_Q871W2 Cluster: Related to acetyl coenzyme A synthetase... 146 3e-34
UniRef50_Q4WAZ5 Cluster: Acetate-CoA ligase, putative; n=1; Aspe... 144 1e-33
UniRef50_Q5QYS0 Cluster: Propionyl-CoA synthetase; n=1; Idiomari... 143 2e-33
UniRef50_A5WC66 Cluster: Propionate--CoA ligase; n=3; Psychrobac... 143 2e-33
UniRef50_A2TC85 Cluster: AMP-dependent synthetase and ligase; n=... 143 3e-33
UniRef50_Q01L46 Cluster: H0502B11.5 protein; n=5; Magnoliophyta|... 136 3e-31
UniRef50_O93730 Cluster: Acetyl-coenzyme A synthetase; n=11; Arc... 136 3e-31
UniRef50_A1CSK5 Cluster: Acyl-CoA synthetase, putative; n=7; Pez... 136 4e-31
UniRef50_Q0I9W4 Cluster: Acetate--CoA ligase; n=19; cellular org... 136 5e-31
UniRef50_Q22UI3 Cluster: AMP-binding enzyme family protein; n=6;... 136 5e-31
UniRef50_Q247U0 Cluster: AMP-binding enzyme family protein; n=1;... 135 8e-31
UniRef50_Q869S4 Cluster: Similar to Bradyrhizobium japonicum. Ac... 133 3e-30
UniRef50_Q0JDG8 Cluster: Os04g0404800 protein; n=8; cellular org... 132 4e-30
UniRef50_Q8YJ48 Cluster: Acetyl-coenzyme A synthetase; n=48; cel... 132 6e-30
UniRef50_A7ATQ7 Cluster: Acetyl-CoA synthetase, putative; n=1; B... 131 1e-29
UniRef50_Q8KBY0 Cluster: Acetyl-coenzyme A synthetase; n=44; cel... 130 2e-29
UniRef50_Q4J9J7 Cluster: Acetyl-coenzyme A synthetase; n=4; Sulf... 130 2e-29
UniRef50_Q89WV5 Cluster: Acetyl-coenzyme A synthetase; n=105; Ba... 129 5e-29
UniRef50_A7HB74 Cluster: AMP-dependent synthetase and ligase; n=... 128 1e-28
UniRef50_Q8ZV36 Cluster: Acetyl-coenzyme A synthetase; n=4; Pyro... 127 2e-28
UniRef50_P27095 Cluster: Acetyl-coenzyme A synthetase; n=12; cel... 127 2e-28
UniRef50_O25686 Cluster: Acetyl-coenzyme A synthetase; n=40; Bac... 126 3e-28
UniRef50_Q9PMD2 Cluster: Acetyl-coenzyme A synthetase; n=143; ce... 126 5e-28
UniRef50_Q8EYG2 Cluster: Acetyl-coenzyme A synthetase; n=76; cel... 124 1e-27
UniRef50_Q7S7A6 Cluster: Putative uncharacterized protein NCU014... 122 8e-27
UniRef50_Q67QN3 Cluster: Acetyl-coenzyme A synthetase; n=6; Bact... 120 3e-26
UniRef50_Q01CP6 Cluster: Acyl-CoA synthetase; n=6; Eukaryota|Rep... 118 8e-26
UniRef50_Q978X5 Cluster: Acetyl-CoA synthetase; n=3; cellular or... 118 8e-26
UniRef50_Q01574 Cluster: Acetyl-coenzyme A synthetase 1; n=40; F... 118 8e-26
UniRef50_Q2RGI0 Cluster: Acetyl-coenzyme A synthetase; n=1; Moor... 118 1e-25
UniRef50_Q9HQU8 Cluster: Acetyl-CoA synthetase; n=11; root|Rep: ... 116 4e-25
UniRef50_Q27549 Cluster: Acetyl-coenzyme A synthetase; n=7; Apic... 115 9e-25
UniRef50_Q7RL40 Cluster: Acetate--CoA ligase-related; n=3; Plasm... 113 2e-24
UniRef50_A6G1J4 Cluster: Acetate--CoA ligase; n=1; Plesiocystis ... 113 4e-24
UniRef50_A2E702 Cluster: AMP-binding enzyme family protein; n=2;... 112 5e-24
UniRef50_Q9NR19 Cluster: Acetyl-coenzyme A synthetase, cytoplasm... 112 7e-24
UniRef50_Q6LEZ6 Cluster: Acetyl-coenzyme a synthetase; n=3; Plas... 111 2e-23
UniRef50_Q81Q80 Cluster: Acetoacetyl-CoA synthase, putative; n=1... 110 3e-23
UniRef50_Q9NUB1 Cluster: Acetyl-coenzyme A synthetase 2-like, mi... 109 4e-23
UniRef50_Q5BYW0 Cluster: SJCHGC03435 protein; n=1; Schistosoma j... 109 6e-23
UniRef50_UPI0000382F9A Cluster: COG0365: Acyl-coenzyme A synthet... 108 8e-23
UniRef50_Q127M4 Cluster: AMP-dependent synthetase and ligase; n=... 105 8e-22
UniRef50_Q557A3 Cluster: Putative uncharacterized protein; n=2; ... 104 2e-21
UniRef50_A5K2B0 Cluster: Acetyl-CoA synthetase, putative; n=1; P... 104 2e-21
UniRef50_Q8SRZ9 Cluster: ACETYLCOENZYME A SYNTHETASE; n=1; Encep... 104 2e-21
UniRef50_Q86AI5 Cluster: Similar to Bradyrhizobium japonicum. Ac... 103 2e-21
UniRef50_Q75JX6 Cluster: Similar to Vibrio cholerae. PrpE protei... 103 2e-21
UniRef50_A1S0M6 Cluster: AMP-dependent synthetase and ligase; n=... 103 3e-21
UniRef50_Q54YU1 Cluster: Putative uncharacterized protein; n=1; ... 103 4e-21
UniRef50_Q97WQ9 Cluster: Acetyl-CoA synthetase; n=3; Sulfolobus|... 101 2e-20
UniRef50_Q4PHQ0 Cluster: Putative uncharacterized protein; n=1; ... 100 2e-20
UniRef50_Q93LL2 Cluster: Acetyl-coenzyme A synthetase; n=165; ce... 100 2e-20
UniRef50_Q5FTV0 Cluster: Acetyl-coenzyme A synthetase; n=1; Gluc... 99 4e-20
UniRef50_Q6U666 Cluster: Putative uncharacterized protein; n=1; ... 99 7e-20
UniRef50_A4WKF4 Cluster: AMP-dependent synthetase and ligase; n=... 98 1e-19
UniRef50_Q8ZUB3 Cluster: Acetyl-coenzyme A synthetase; n=4; Arch... 97 2e-19
UniRef50_Q72J94 Cluster: Acetyl-coenzyme A synthetase; n=2; Ther... 97 3e-19
UniRef50_Q1JYJ4 Cluster: AMP-dependent synthetase and ligase; n=... 97 4e-19
UniRef50_Q0FW37 Cluster: Acyl-CoA synthetase; n=1; Roseovarius s... 97 4e-19
UniRef50_A7DME3 Cluster: AMP-dependent synthetase and ligase; n=... 97 4e-19
UniRef50_Q39MW7 Cluster: AMP-dependent synthetase and ligase; n=... 96 5e-19
UniRef50_Q140P4 Cluster: Putative acetyl-CoA synthetase and liga... 96 5e-19
UniRef50_A4A7V6 Cluster: Acetyl-coenzyme A synthetase/GroES-like... 96 5e-19
UniRef50_Q55GU6 Cluster: Putative acetyl-CoA synthetase; n=3; Di... 96 6e-19
UniRef50_Q9HLJ9 Cluster: Acetyl-CoA synthetase related protein; ... 95 8e-19
UniRef50_Q5P1M8 Cluster: Acyl-CoA synthetase; n=2; Azoarcus|Rep:... 95 1e-18
UniRef50_Q4QBC0 Cluster: Acetyl-CoA synthetase, putative; n=6; E... 94 2e-18
UniRef50_Q9YCA8 Cluster: Acetyl-coenzyme A synthetase; n=2; Arch... 94 2e-18
UniRef50_Q9Y8M8 Cluster: Acetyl-coenzyme A synthetase; n=1; Aero... 94 2e-18
UniRef50_Q9RX55 Cluster: Acetyl-CoA synthase; n=4; cellular orga... 93 4e-18
UniRef50_Q6L1R5 Cluster: Acetyl-coenzyme A synthetase; n=1; Picr... 90 3e-17
UniRef50_A3VFU7 Cluster: Acetoacetyl-CoA synthase; n=1; Rhodobac... 89 7e-17
UniRef50_Q5V498 Cluster: Acyl-coenzyme A synthetases; n=5; Halob... 89 7e-17
UniRef50_Q4ST59 Cluster: Chromosome undetermined SCAF14300, whol... 87 2e-16
UniRef50_Q3E187 Cluster: AMP-dependent synthetase and ligase:Eno... 86 7e-16
UniRef50_Q0RXR5 Cluster: Acetate--CoA ligase; n=1; Rhodococcus s... 85 2e-15
UniRef50_Q97WK0 Cluster: Acetyl-CoA synthetase; n=4; Sulfolobace... 84 3e-15
UniRef50_A7JC22 Cluster: Predicted protein; n=1; Francisella tul... 83 4e-15
UniRef50_A5UY60 Cluster: AMP-dependent synthetase and ligase; n=... 83 6e-15
UniRef50_A3WE14 Cluster: Acetyl-coenzyme A synthetase; n=1; Eryt... 81 2e-14
UniRef50_Q01NM8 Cluster: AMP-dependent synthetase and ligase; n=... 79 1e-13
UniRef50_Q54YU2 Cluster: Putative uncharacterized protein; n=1; ... 78 1e-13
UniRef50_O30042 Cluster: Acetyl-CoA synthetase; n=1; Archaeoglob... 77 3e-13
UniRef50_Q397N8 Cluster: Acetoacetyl-CoA synthase; n=5; Bacteria... 76 5e-13
UniRef50_A3W6I7 Cluster: AMP-dependent synthetase and ligase; n=... 76 7e-13
UniRef50_A4T5I6 Cluster: Acetoacetyl-CoA synthase; n=2; Mycobact... 74 2e-12
UniRef50_Q9KZN9 Cluster: Acetoacetyl-CoA synthetase; n=5; Actino... 73 7e-12
UniRef50_A5WDS3 Cluster: AMP-dependent synthetase and ligase; n=... 73 7e-12
UniRef50_Q12HA7 Cluster: Acetoacetyl-CoA synthase precursor; n=6... 69 6e-11
UniRef50_Q86JR9 Cluster: Putative uncharacterized protein; n=2; ... 68 2e-10
UniRef50_P39062 Cluster: Acetyl-coenzyme A synthetase; n=41; cel... 65 1e-09
UniRef50_Q5KZW6 Cluster: Acetoacetyl-CoA synthetase; n=20; Bacte... 64 2e-09
UniRef50_A1IEB0 Cluster: Acetoacetyl-CoA synthase; n=1; Candidat... 64 2e-09
UniRef50_Q8ZV30 Cluster: Acetyl-coenzyme A synthetase; n=6; Ther... 64 2e-09
UniRef50_UPI00005102FE Cluster: COG0365: Acyl-coenzyme A synthet... 64 3e-09
UniRef50_A4QIB2 Cluster: Putative uncharacterized protein; n=1; ... 64 3e-09
UniRef50_Q8IWD2 Cluster: Acetoacetyl-CoA synthetase; n=53; Eumet... 63 4e-09
UniRef50_Q0S3K9 Cluster: Acetoacetate--CoA ligase; n=10; Actinom... 63 5e-09
UniRef50_A4TEH9 Cluster: Acetyl-CoA synthetase precursor; n=1; M... 62 7e-09
UniRef50_Q11QU1 Cluster: Acetyl-CoA synthetase; n=1; Cytophaga h... 62 1e-08
UniRef50_A4TUE0 Cluster: Acyl-coenzyme A synthetases/AMP-(Fatty)... 61 2e-08
UniRef50_A1W234 Cluster: Acetoacetyl-CoA synthase; n=2; Comamona... 61 2e-08
UniRef50_A0JS90 Cluster: AMP-dependent synthetase and ligase; n=... 61 2e-08
UniRef50_A1VP64 Cluster: Acetoacetyl-CoA synthase; n=2; Comamona... 61 2e-08
UniRef50_Q0A597 Cluster: AMP-dependent synthetase and ligase; n=... 60 3e-08
UniRef50_A7IGG1 Cluster: AMP-dependent synthetase and ligase; n=... 60 3e-08
UniRef50_Q7W0W3 Cluster: Acetyl-CoA synthetase; n=2; Bordetella|... 60 4e-08
UniRef50_Q8ESW2 Cluster: Acetoacetyl-CoA synthetase; n=1; Oceano... 60 5e-08
UniRef50_Q8F6X6 Cluster: Acetyl-CoA synthetase; n=3; Bacteria|Re... 59 9e-08
UniRef50_O28347 Cluster: Long-chain-fatty-acid--CoA ligase; n=1;... 58 1e-07
UniRef50_A6C4K4 Cluster: Acetate--CoA ligase; n=1; Planctomyces ... 57 4e-07
UniRef50_Q5UWB7 Cluster: Acyl-coenzyme A synthetases; n=2; Halob... 57 4e-07
UniRef50_Q39MD9 Cluster: AMP-dependent synthetase and ligase; n=... 56 5e-07
UniRef50_Q0SJB1 Cluster: Acetoacetate--CoA ligase; n=1; Rhodococ... 56 5e-07
UniRef50_Q5KW92 Cluster: Acetyl-CoA synthetase; n=2; Geobacillus... 56 6e-07
UniRef50_Q2J785 Cluster: Acetoacetyl-CoA synthase; n=5; Actinoba... 56 8e-07
UniRef50_Q7WPR9 Cluster: AMP-binding enzyme; n=5; Burkholderiale... 55 1e-06
UniRef50_A3JB96 Cluster: Acetyl-coenzyme A synthetase; n=6; Gamm... 55 1e-06
UniRef50_Q5P869 Cluster: 3-hydroxybenzoate CoA ligase; n=2; Rhod... 53 4e-06
UniRef50_A4FEF5 Cluster: AMP-dependent synthetase and ligase; n=... 53 4e-06
UniRef50_Q8YBS1 Cluster: ACETYL-COENZYME A SYNTHETASE; n=38; Pro... 53 6e-06
UniRef50_A6FGF6 Cluster: Probable AMP-binding enzyme; n=1; Morit... 53 6e-06
UniRef50_A0KEL2 Cluster: Acetoacetyl-CoA synthase; n=2; Aeromona... 53 6e-06
UniRef50_Q83DG9 Cluster: Acetoacetyl-CoA synthase; n=5; Gammapro... 51 2e-05
UniRef50_A2SSU3 Cluster: AMP-dependent synthetase and ligase; n=... 51 2e-05
UniRef50_UPI0000510398 Cluster: COG0365: Acyl-coenzyme A synthet... 51 2e-05
UniRef50_A6QV87 Cluster: Putative uncharacterized protein; n=2; ... 51 2e-05
UniRef50_A7I4G3 Cluster: AMP-dependent synthetase and ligase; n=... 50 3e-05
UniRef50_P27096 Cluster: Uncharacterized 16.9 kDa protein in acs... 50 4e-05
UniRef50_Q47NR9 Cluster: Non-ribosomal peptide synthase:Amino ac... 50 5e-05
UniRef50_A5UV13 Cluster: AMP-dependent synthetase and ligase; n=... 50 5e-05
UniRef50_A1SEZ8 Cluster: AMP-dependent synthetase and ligase; n=... 50 5e-05
UniRef50_A0Y863 Cluster: Long-chain fatty acid--CoA ligase; n=1;... 50 5e-05
UniRef50_A0LK08 Cluster: AMP-dependent synthetase and ligase; n=... 50 5e-05
UniRef50_Q6MYU7 Cluster: Acetoacetyl-coa synthetase, putative; n... 50 5e-05
UniRef50_Q3IUK7 Cluster: Acyl-CoA synthetase I 5; n=2; Halobacte... 50 5e-05
UniRef50_UPI000038E2AC Cluster: hypothetical protein Faci_030001... 49 9e-05
UniRef50_Q8G3C8 Cluster: Acetoacetyl-CoA synthase; n=36; Proteob... 49 9e-05
UniRef50_Q11M02 Cluster: Acetoacetyl-CoA synthase; n=7; Proteoba... 49 9e-05
UniRef50_Q7WNN5 Cluster: Putative long-chain-fatty-acid-CoA liga... 48 1e-04
UniRef50_Q39T59 Cluster: AMP-dependent synthetase and ligase; n=... 48 1e-04
UniRef50_A0LLK9 Cluster: Benzoate-CoA ligase family; n=1; Syntro... 48 1e-04
UniRef50_Q2H9I4 Cluster: Putative uncharacterized protein; n=1; ... 48 1e-04
UniRef50_Q13BW2 Cluster: AMP-dependent synthetase and ligase; n=... 48 2e-04
UniRef50_Q0SGL4 Cluster: AMP-dependent synthetase; n=1; Rhodococ... 48 2e-04
UniRef50_Q6A9A4 Cluster: Acetyl-coenzyme A synthetase; n=1; Prop... 48 2e-04
UniRef50_UPI000038CCA4 Cluster: COG0318: Acyl-CoA synthetases (A... 47 3e-04
UniRef50_Q0S7A8 Cluster: 2,3-dihydroxybenzoate-AMP ligase/ S-dih... 47 3e-04
UniRef50_Q18HL6 Cluster: O-succinylbenzoic acid--CoA ligase; n=1... 47 3e-04
UniRef50_Q87H07 Cluster: Acetyl-CoA synthase; n=13; Vibrionales|... 47 4e-04
UniRef50_Q5KZW0 Cluster: Long-chain fatty-acid-CoA ligase; n=6; ... 47 4e-04
UniRef50_Q3IWF1 Cluster: AMP-binding enzyme; n=6; Alphaproteobac... 47 4e-04
UniRef50_Q2BI30 Cluster: Acetyl-coenzyme A synthetase; n=1; Nept... 47 4e-04
UniRef50_A1UDV2 Cluster: AMP-dependent synthetase and ligase; n=... 47 4e-04
UniRef50_Q0WQ54 Cluster: Acetyl-CoA synthetase-like protein; n=1... 47 4e-04
UniRef50_Q70C44 Cluster: Non-ribosomal peptide synthase; n=1; Xa... 46 5e-04
UniRef50_Q0LLG2 Cluster: Amino acid adenylation; n=1; Herpetosip... 46 5e-04
UniRef50_Q2NH56 Cluster: Predicted acyl-CoA synthetase; n=1; Met... 46 5e-04
UniRef50_Q9Z3R3 Cluster: Acetoacetyl-coenzyme A synthetase; n=7;... 46 5e-04
UniRef50_Q21UY9 Cluster: AMP-dependent synthetase and ligase; n=... 46 7e-04
UniRef50_Q0RL93 Cluster: Putative uncharacterized protein; n=1; ... 46 7e-04
UniRef50_A3PSP1 Cluster: AMP-dependent synthetase and ligase; n=... 46 7e-04
UniRef50_A2QQX9 Cluster: Contig An08c0110, complete genome; n=6;... 46 7e-04
UniRef50_Q7NVV9 Cluster: Synthetase CbsF; n=3; cellular organism... 46 9e-04
UniRef50_Q939Z1 Cluster: Peptide synthetase; n=7; Actinomycetale... 46 9e-04
UniRef50_Q21E99 Cluster: Amino acid adenylation; n=2; Bacteria|R... 46 9e-04
UniRef50_A4TVS6 Cluster: AMP-dependent synthetase and ligase; n=... 46 9e-04
UniRef50_A7SU89 Cluster: Predicted protein; n=1; Nematostella ve... 46 9e-04
UniRef50_Q62F86 Cluster: AMP-binding domain protein; n=14; Burkh... 45 0.001
UniRef50_Q13I22 Cluster: Putative AMP-dependent synthetase and l... 45 0.001
UniRef50_A0Z3I7 Cluster: Acyl-CoA synthase; n=1; marine gamma pr... 45 0.001
UniRef50_Q5TF43 Cluster: Acyl-CoA synthetase short-chain family ... 45 0.001
UniRef50_Q45R83 Cluster: Peptide synthetase; n=3; Actinobacteria... 45 0.002
UniRef50_Q24N89 Cluster: Putative uncharacterized protein; n=1; ... 45 0.002
UniRef50_A0QZD4 Cluster: Acetyl-coenzyme A synthetase; n=3; Cory... 45 0.002
UniRef50_Q9HEI8 Cluster: Related to acetoacetyl-CoA synthetase; ... 45 0.002
UniRef50_UPI0000165EEF Cluster: acyl-CoA synthase; n=1; Deinococ... 44 0.002
UniRef50_Q9KLB7 Cluster: Acetyl-CoA synthase; n=21; Vibrio|Rep: ... 44 0.002
UniRef50_Q7W4Q6 Cluster: Putative fatty acid CoA ligase; n=3; Bo... 44 0.002
UniRef50_Q3M5Z4 Cluster: AMP-dependent synthetase and ligase; n=... 44 0.002
UniRef50_Q50E73 Cluster: Peptide synthetase 2; n=1; Streptomyces... 44 0.003
UniRef50_Q1GUE8 Cluster: AMP-dependent synthetase and ligase; n=... 44 0.003
UniRef50_A3Z2Q3 Cluster: Acyl-CoA synthase; n=1; Synechococcus s... 44 0.003
UniRef50_A0Z4Z7 Cluster: AMP-dependent synthetase and ligase; n=... 44 0.003
UniRef50_A0LVM6 Cluster: Acetoacetyl-CoA synthase; n=5; Bacteria... 44 0.003
UniRef50_A7SNY7 Cluster: Predicted protein; n=1; Nematostella ve... 44 0.003
UniRef50_Q2W0K6 Cluster: Acyl-coenzyme A synthetase/AMP-(Fatty) ... 44 0.003
UniRef50_Q9LCU0 Cluster: PstD; n=2; Mycobacterium avium|Rep: Pst... 44 0.003
UniRef50_A6V359 Cluster: Linear gramicidin synthetase subunit C;... 44 0.003
UniRef50_Q9C8A3 Cluster: Acetyl-CoA synthetase, putative; 45051-... 44 0.003
UniRef50_Q6L1D6 Cluster: Long chain fatty acid CoA ligase; n=1; ... 44 0.003
UniRef50_Q83MG9 Cluster: Probable crotonobetaine/carnitine-CoA l... 44 0.003
UniRef50_Q3KF66 Cluster: Amino acid adenylation; n=2; Pseudomona... 43 0.005
UniRef50_Q140M1 Cluster: Putative long chain fatty acid CoA liga... 43 0.005
UniRef50_Q124C5 Cluster: AMP-dependent synthetase and ligase; n=... 43 0.005
UniRef50_A7DD68 Cluster: AMP-dependent synthetase and ligase; n=... 43 0.005
UniRef50_A5A9U3 Cluster: Mps2 protein; n=2; Mycobacterium|Rep: M... 43 0.005
UniRef50_A4BLS1 Cluster: Putative non-ribosomal peptide synthase... 43 0.005
UniRef50_A0K0Y8 Cluster: AMP-dependent synthetase and ligase; n=... 43 0.005
UniRef50_Q7CT27 Cluster: AGR_L_2309p; n=2; Agrobacterium tumefac... 43 0.006
UniRef50_A6VYF7 Cluster: Amino acid adenylation domain; n=1; Mar... 43 0.006
UniRef50_A3P7D6 Cluster: Non-ribosomal peptide synthase; n=34; B... 43 0.006
UniRef50_Q4PHX8 Cluster: Putative uncharacterized protein; n=1; ... 43 0.006
UniRef50_UPI0000E45C70 Cluster: PREDICTED: hypothetical protein;... 42 0.008
UniRef50_Q6MIK4 Cluster: AMP-ligase; n=1; Bdellovibrio bacteriov... 42 0.008
UniRef50_Q3M1P5 Cluster: Amino acid adenylation; n=2; Cyanobacte... 42 0.008
UniRef50_Q3WHP4 Cluster: AMP-dependent synthetase and ligase; n=... 42 0.008
UniRef50_Q06YZ2 Cluster: Nonribosomal peptide synthetase; n=1; S... 42 0.008
UniRef50_A3RXA3 Cluster: AMP-(Fatty)acid ligases; n=6; Burkholde... 42 0.008
UniRef50_Q0D0Z7 Cluster: Putative uncharacterized protein; n=2; ... 42 0.008
UniRef50_Q6KZU2 Cluster: Acetoacetyl-CoA synthetase; n=1; Picrop... 42 0.008
UniRef50_Q5P0J2 Cluster: 4-hydroxybenzoate CoA ligase; n=1; Azoa... 42 0.011
UniRef50_P71716 Cluster: BIFUNCTIONAL ENZYME MBTA: SALICYL-AMP L... 42 0.011
UniRef50_Q1V1I6 Cluster: Acetoacetyl-CoA synthase; n=2; Bacteria... 42 0.011
UniRef50_Q0LP24 Cluster: Amino acid adenylation; n=1; Herpetosip... 42 0.011
UniRef50_A6UHL1 Cluster: AMP-dependent synthetase and ligase; n=... 42 0.011
UniRef50_A6P624 Cluster: Nonribosomal peptide synthetase; n=1; M... 42 0.011
UniRef50_A3VQJ0 Cluster: Acyl-CoA synthase; n=1; Parvularcula be... 42 0.011
UniRef50_Q2UH98 Cluster: Acyl-CoA synthetases; n=4; Eurotiomycet... 42 0.011
UniRef50_Q7N5R3 Cluster: Complete genome; segment 7/17; n=1; Pho... 42 0.014
UniRef50_Q9L8H4 Cluster: Actinomycin synthetase III; n=1; Strept... 42 0.014
UniRef50_Q5DIU0 Cluster: PvdI; n=3; cellular organisms|Rep: PvdI... 42 0.014
UniRef50_Q3WFP5 Cluster: AMP-dependent synthetase and ligase; n=... 42 0.014
UniRef50_Q3WCA8 Cluster: AMP-dependent synthetase and ligase; n=... 42 0.014
UniRef50_Q3L908 Cluster: Putative fatty-acid--CoA ligase; n=1; R... 42 0.014
UniRef50_O68487 Cluster: Actinomycin synthetase II; n=1; Strepto... 42 0.014
UniRef50_A6GK66 Cluster: Non-ribosomal peptide synthetase; n=1; ... 42 0.014
UniRef50_A4X9C6 Cluster: Thioester reductase domain; n=2; Salini... 42 0.014
UniRef50_A4FFC7 Cluster: Putative fatty-acid--CoA ligase; n=1; S... 42 0.014
UniRef50_A7RFX5 Cluster: Predicted protein; n=1; Nematostella ve... 42 0.014
UniRef50_Q82GQ6 Cluster: Putative cyclohex-1-ene-1-carboxylate:C... 41 0.019
UniRef50_Q4JSW1 Cluster: Acyl-CoA synthetase; n=1; Corynebacteri... 41 0.019
UniRef50_Q8RNW9 Cluster: Adenylate-forming enzyme; n=2; Streptom... 41 0.019
UniRef50_Q28MM6 Cluster: AMP-dependent synthetase and ligase; n=... 41 0.019
UniRef50_Q1PUQ3 Cluster: Similar to long chain acyl-coenzyme A s... 41 0.019
UniRef50_Q12IB7 Cluster: Amino acid adenylation; n=1; Shewanella... 41 0.019
UniRef50_Q0SBN7 Cluster: Probable acid-CoA ligase; n=1; Rhodococ... 41 0.019
UniRef50_Q0G336 Cluster: Peptide synthetase; n=1; Fulvimarina pe... 41 0.019
UniRef50_A5ERA9 Cluster: Arthrofactin synthetase/syringopeptin s... 41 0.019
UniRef50_A0V7F5 Cluster: AMP-dependent synthetase and ligase; n=... 41 0.019
UniRef50_Q97YI1 Cluster: Acetyl-CoA synthetase (Acetate-CoA liga... 41 0.019
UniRef50_Q9Z4X6 Cluster: CDA peptide synthetase I; n=4; cellular... 41 0.025
UniRef50_Q62C03 Cluster: Nonribosomal peptide synthetase DhbF; n... 41 0.025
UniRef50_Q53005 Cluster: 4-hydroxybenzoate: coenzyme A ligase; n... 41 0.025
UniRef50_Q3WJL5 Cluster: AMP-dependent synthetase and ligase; n=... 41 0.025
UniRef50_Q11E51 Cluster: AMP-dependent synthetase and ligase; n=... 41 0.025
UniRef50_Q0S4D9 Cluster: CoA ligase; n=2; Nocardiaceae|Rep: CoA ... 41 0.025
UniRef50_A6V8H5 Cluster: Long-chain-fatty-acid--CoA ligase, puta... 41 0.025
UniRef50_A6DB12 Cluster: Acyl-CoA synthase; n=1; Caminibacter me... 41 0.025
UniRef50_A5V315 Cluster: AMP-dependent synthetase and ligase; n=... 41 0.025
UniRef50_A4SX85 Cluster: AMP-dependent synthetase and ligase; n=... 41 0.025
UniRef50_A4KVL6 Cluster: Non-ribosomal peptide synthetase module... 41 0.025
UniRef50_A3Q4D1 Cluster: AMP-dependent synthetase and ligase; n=... 41 0.025
UniRef50_A3JMY8 Cluster: Non-ribosomal peptide synthetase; n=4; ... 41 0.025
UniRef50_A7ECX0 Cluster: Putative uncharacterized protein; n=1; ... 41 0.025
UniRef50_Q8CV01 Cluster: 2,3-dihydroxybenzoate-AMP ligase; n=2; ... 40 0.033
UniRef50_Q5E2J5 Cluster: Long-chain-fatty-acid--CoA ligase; n=4;... 40 0.033
UniRef50_Q399N2 Cluster: AMP-dependent synthetase and ligase; n=... 40 0.033
UniRef50_Q1GM48 Cluster: Acetoacetyl-CoA synthase; n=3; Proteoba... 40 0.033
UniRef50_Q1D5W2 Cluster: Non-ribosomal peptide synthetase/polyke... 40 0.033
UniRef50_Q1ATG8 Cluster: AMP-dependent synthetase and ligase; n=... 40 0.033
UniRef50_Q13G91 Cluster: Putative AMP-dependent synthetase and l... 40 0.033
UniRef50_Q0SKB1 Cluster: Acyl CoA synthetase, AMP-binding protei... 40 0.033
UniRef50_Q0SEC4 Cluster: Possible long-chain-fatty-acid-CoA liga... 40 0.033
UniRef50_A7BC57 Cluster: Putative uncharacterized protein; n=1; ... 40 0.033
UniRef50_A6W8M8 Cluster: AMP-dependent synthetase and ligase; n=... 40 0.033
UniRef50_A5UZF0 Cluster: AMP-dependent synthetase and ligase; n=... 40 0.033
UniRef50_A4FF93 Cluster: AMP-dependent synthetase and ligase; n=... 40 0.033
UniRef50_A3ZYI7 Cluster: Long-chain fatty-acid-CoA ligase; n=1; ... 40 0.033
UniRef50_A1G2R8 Cluster: Amino acid adenylation domain; n=1; Sal... 40 0.033
UniRef50_A0YE26 Cluster: Putative crotonobetaine/carnitine-CoA l... 40 0.033
UniRef50_A0QH53 Cluster: Linear gramicidin synthetase subunit D;... 40 0.033
UniRef50_Q55RP2 Cluster: Putative uncharacterized protein; n=2; ... 40 0.033
UniRef50_UPI0001556387 Cluster: PREDICTED: similar to acyl-CoA s... 40 0.043
UniRef50_Q74E61 Cluster: Long-chain-fatty-acid--CoA ligase, puta... 40 0.043
UniRef50_Q5P655 Cluster: Cyclohexanecarboxylate-CoA ligase; n=5;... 40 0.043
UniRef50_Q5KZX6 Cluster: Hypothetical conserved protein; n=1; Ge... 40 0.043
UniRef50_Q2T5X7 Cluster: Peptide synthetase, putative; n=9; Burk... 40 0.043
UniRef50_Q10878 Cluster: POSSIBLE FATTY-ACID-CoA LIGASE FADD10; ... 40 0.043
UniRef50_Q0YRD8 Cluster: Amino acid adenylation; n=2; cellular o... 40 0.043
UniRef50_Q0SK68 Cluster: Non-ribosomal peptide synthetase; n=1; ... 40 0.043
UniRef50_P95819 Cluster: Pristinamycin I synthetase I; n=8; Bact... 40 0.043
UniRef50_A6V024 Cluster: Amino acid adenylation domain; n=1; Pse... 40 0.043
UniRef50_A3DBZ4 Cluster: AMP-dependent synthetase and ligase; n=... 40 0.043
UniRef50_A1G2S7 Cluster: Amino acid adenylation domain; n=1; Sal... 40 0.043
UniRef50_Q89L37 Cluster: Fatty acid CoA ligase; n=15; Proteobact... 40 0.057
UniRef50_Q8GGR4 Cluster: Nonribosomal peptide synthetase; n=1; S... 40 0.057
UniRef50_Q18UZ8 Cluster: AMP-dependent synthetase and ligase; n=... 40 0.057
UniRef50_Q13PB0 Cluster: Putative acid-CoA ligase; n=1; Burkhold... 40 0.057
UniRef50_Q0SEL8 Cluster: Non-ribosomal peptide synthetase; n=1; ... 40 0.057
UniRef50_Q0S5F4 Cluster: Non-ribosomal peptide synthetase; n=1; ... 40 0.057
UniRef50_A6FC19 Cluster: Acyl-CoA synthase; n=1; Moritella sp. P... 40 0.057
UniRef50_A4JPB0 Cluster: Amino acid adenylation domain; n=1; Bur... 40 0.057
UniRef50_Q0DL03 Cluster: Os05g0132100 protein; n=6; Magnoliophyt... 40 0.057
UniRef50_A7SE80 Cluster: Predicted protein; n=1; Nematostella ve... 40 0.057
UniRef50_UPI00006DBBC1 Cluster: COG0365: Acyl-coenzyme A synthet... 39 0.075
UniRef50_Q8YTR4 Cluster: All2649 protein; n=3; Nostocaceae|Rep: ... 39 0.075
UniRef50_Q8NTA7 Cluster: Acyl-CoA synthetases (AMP-forming)/AMP-... 39 0.075
UniRef50_Q6D739 Cluster: Non-ribosomal peptide synthetase; n=3; ... 39 0.075
UniRef50_Q5LQF1 Cluster: AMP-binding enzyme; n=1; Silicibacter p... 39 0.075
UniRef50_Q47NS0 Cluster: Amino acid adenylation; n=1; Thermobifi... 39 0.075
UniRef50_Q8GGQ3 Cluster: Nonribosomal peptide synthetase; n=2; S... 39 0.075
UniRef50_Q84HC5 Cluster: Adenylate ligase; n=3; Actinomycetales|... 39 0.075
UniRef50_Q6J677 Cluster: Acyl-CoA synthetase; n=1; Collimonas fu... 39 0.075
UniRef50_Q1GWS9 Cluster: AMP-dependent synthetase and ligase; n=... 39 0.075
UniRef50_A1RCH2 Cluster: Putative coenzyme A ligase; n=1; Arthro... 39 0.075
UniRef50_A5C4N6 Cluster: Putative uncharacterized protein; n=1; ... 39 0.075
UniRef50_A2Y9K6 Cluster: Putative uncharacterized protein; n=3; ... 39 0.075
UniRef50_Q7SI43 Cluster: Putative uncharacterized protein NCU006... 39 0.075
UniRef50_UPI00015B53A6 Cluster: PREDICTED: similar to AMP depend... 39 0.100
UniRef50_UPI0000E478FD Cluster: PREDICTED: hypothetical protein;... 39 0.100
UniRef50_Q93H04 Cluster: Non-ribosomal peptide synthetase; n=1; ... 39 0.100
UniRef50_Q8YWC0 Cluster: All1695 protein; n=1; Nostoc sp. PCC 71... 39 0.100
UniRef50_Q3A444 Cluster: Long-chain acyl-CoA synthetases; n=4; D... 39 0.100
UniRef50_Q9RLP6 Cluster: Peptide synthetase; n=18; cellular orga... 39 0.100
UniRef50_Q7CRI7 Cluster: AGR_L_3476p; n=2; Agrobacterium tumefac... 39 0.100
UniRef50_Q0RF46 Cluster: Putative long-chain-fatty-acid-CoA liga... 39 0.100
UniRef50_O07944 Cluster: Pristinamycin I synthase 3 and 4; n=2; ... 39 0.100
UniRef50_A4X2Q7 Cluster: AMP-dependent synthetase and ligase; n=... 39 0.100
UniRef50_A3PXA5 Cluster: AMP-dependent synthetase and ligase; n=... 39 0.100
UniRef50_A1SPQ8 Cluster: AMP-dependent synthetase and ligase; n=... 39 0.100
UniRef50_A0FXQ3 Cluster: Amino acid adenylation domain; n=2; Bac... 39 0.100
UniRef50_A0JJU1 Cluster: Tenellin polyketide synthase; n=3; Asco... 39 0.100
UniRef50_Q4J776 Cluster: Acetyl-coenzyme A synthetase; n=2; Sulf... 39 0.100
UniRef50_Q08787 Cluster: Surfactin synthetase subunit 3; n=9; Ba... 39 0.100
UniRef50_Q9KBC2 Cluster: Long-chain acyl-CoA synthetase; n=2; Ba... 38 0.13
UniRef50_Q989U0 Cluster: Mlr6282 protein; n=1; Mesorhizobium lot... 38 0.13
UniRef50_Q7NXZ0 Cluster: Enterobactin synthetase component F; n=... 38 0.13
UniRef50_Q7N2F7 Cluster: Complete genome; segment 11/17; n=4; Ph... 38 0.13
UniRef50_Q62C88 Cluster: Thiotemplate mechanism natural product ... 38 0.13
UniRef50_Q5LKI0 Cluster: Benzoate-coenzyme A ligase; n=33; Bacte... 38 0.13
UniRef50_Q4ZVI2 Cluster: Amino acid adenylation; n=4; Pseudomona... 38 0.13
UniRef50_Q39TG8 Cluster: AMP-dependent synthetase and ligase; n=... 38 0.13
UniRef50_Q8KR71 Cluster: Nonribosomal peptide synthetase PhbF; n... 38 0.13
UniRef50_Q6SK65 Cluster: Peptide synthetase; n=5; cellular organ... 38 0.13
UniRef50_Q2PC83 Cluster: Putative polyketide synthase; n=2; Acti... 38 0.13
UniRef50_Q1D438 Cluster: Non-ribosomal peptide synthase; n=8; Ba... 38 0.13
UniRef50_Q11F62 Cluster: Amino acid adenylation domain; n=1; Mes... 38 0.13
UniRef50_Q0LLQ8 Cluster: Amino acid adenylation; n=2; Herpetosip... 38 0.13
UniRef50_A5G412 Cluster: Amino acid adenylation domain; n=3; Del... 38 0.13
UniRef50_A4PHL4 Cluster: Non ribosomal peptide synthetase for vi... 38 0.13
UniRef50_A2U676 Cluster: AMP-dependent synthetase and ligase; n=... 38 0.13
UniRef50_A1GFR6 Cluster: AMP-dependent synthetase and ligase; n=... 38 0.13
UniRef50_A0Z1E2 Cluster: Acetyl-coenzyme A synthetase; n=1; mari... 38 0.13
UniRef50_A0V818 Cluster: AMP-dependent synthetase and ligase; n=... 38 0.13
UniRef50_A0K352 Cluster: AMP-dependent synthetase and ligase; n=... 38 0.13
UniRef50_A0HJN0 Cluster: AMP-dependent synthetase and ligase; n=... 38 0.13
UniRef50_A2WTT6 Cluster: Putative uncharacterized protein; n=1; ... 38 0.13
UniRef50_O28423 Cluster: 2,3-dihydrosybenzoate-AMP ligase; n=1; ... 38 0.13
UniRef50_UPI00003C8454 Cluster: hypothetical protein Faci_030002... 38 0.17
UniRef50_Q5L252 Cluster: AMP-binding enzyme; n=3; Bacillaceae|Re... 38 0.17
UniRef50_Q5KY15 Cluster: Long-chain fatty-acid-CoA ligase; n=1; ... 38 0.17
UniRef50_Q2LXW4 Cluster: 2,3-dihydroxybenzoate-AMP ligase; n=1; ... 38 0.17
UniRef50_Q2JA64 Cluster: Amino acid adenylation; n=3; Actinomyce... 38 0.17
UniRef50_Q1IBI9 Cluster: Putative non-ribosomal peptide syntheta... 38 0.17
UniRef50_Q0S6F3 Cluster: Non-ribosomal peptide synthetase; n=2; ... 38 0.17
UniRef50_Q0K0K4 Cluster: Non-ribosomal peptide synthetase; n=1; ... 38 0.17
UniRef50_O52507 Cluster: Serrawettin synthase; n=1; Serratia liq... 38 0.17
UniRef50_A6FX12 Cluster: Putative long-chain fatty acid--CoA lig... 38 0.17
UniRef50_A0YE98 Cluster: AMP-dependent synthetase and ligase; n=... 38 0.17
UniRef50_Q7QTM8 Cluster: GLP_0_31804_34101; n=2; Giardia lamblia... 38 0.17
UniRef50_Q0UDN6 Cluster: Putative uncharacterized protein; n=1; ... 38 0.17
UniRef50_O29418 Cluster: Long-chain-fatty-acid--CoA ligase; n=4;... 38 0.17
UniRef50_Q9M0X9 Cluster: 4-coumarate--CoA ligase-like 7; n=1; Ar... 38 0.17
UniRef50_Q8XQ52 Cluster: Putative acyl-coa synthetases(Amp-formi... 38 0.23
UniRef50_Q4KES9 Cluster: Nonribosomal peptide synthetase; n=6; B... 38 0.23
UniRef50_Q4KAY7 Cluster: Pyochelin synthetase E; n=1; Pseudomona... 38 0.23
UniRef50_Q2SFM4 Cluster: Non-ribosomal peptide synthetase module... 38 0.23
UniRef50_Q7B6H0 Cluster: Cyclohex-1-ene-1-carboxylate CoA ligase... 38 0.23
UniRef50_Q20CI8 Cluster: CesB; n=7; cellular organisms|Rep: CesB... 38 0.23
UniRef50_Q0X0B9 Cluster: Putative non-ribosomal peptide syntheta... 38 0.23
UniRef50_Q0S7M5 Cluster: AMP-binding CoA ligase; n=1; Rhodococcu... 38 0.23
UniRef50_O54666 Cluster: RifA; n=4; Actinomycetales|Rep: RifA - ... 38 0.23
UniRef50_A6G5C8 Cluster: Benzoate-CoA ligase family protein; n=1... 38 0.23
UniRef50_A3JR31 Cluster: Putative uncharacterized protein; n=1; ... 38 0.23
UniRef50_A0Z9R9 Cluster: Putative uncharacterized protein; n=1; ... 38 0.23
UniRef50_A7RNA0 Cluster: Predicted protein; n=1; Nematostella ve... 38 0.23
UniRef50_Q5ATG8 Cluster: Putative uncharacterized protein; n=1; ... 38 0.23
UniRef50_P48633 Cluster: High-molecular-weight protein 2; n=26; ... 38 0.23
UniRef50_Q9X7Y5 Cluster: Putative long chain fatty acid coA liga... 37 0.30
UniRef50_Q93H70 Cluster: Non-ribosomal peptide synthetase; n=1; ... 37 0.30
UniRef50_Q8R8N5 Cluster: Acyl-CoA synthetases (AMP-forming)/AMP-... 37 0.30
UniRef50_Q89Q01 Cluster: Blr3329 protein; n=1; Bradyrhizobium ja... 37 0.30
UniRef50_Q6D738 Cluster: Non-ribosomal peptide synthetase; n=3; ... 37 0.30
UniRef50_Q4ZT75 Cluster: Amino acid adenylation; n=2; Pseudomona... 37 0.30
UniRef50_Q47YU9 Cluster: Acid-CoA ligase family protein; n=1; Co... 37 0.30
UniRef50_Q46TM5 Cluster: AMP-dependent synthetase and ligase; n=... 37 0.30
UniRef50_Q4C639 Cluster: Amino acid adenylation; n=1; Crocosphae... 37 0.30
UniRef50_Q333V5 Cluster: NRPS protein; n=2; Actinomycetales|Rep:... 37 0.30
UniRef50_Q2I765 Cluster: PlaP4; n=9; Bacteria|Rep: PlaP4 - Strep... 37 0.30
UniRef50_Q1ITX8 Cluster: AMP-dependent synthetase and ligase; n=... 37 0.30
UniRef50_Q0YRE2 Cluster: Amino acid adenylation; n=1; Chlorobium... 37 0.30
UniRef50_Q0SGA4 Cluster: Acetate--CoA ligase; n=2; Corynebacteri... 37 0.30
UniRef50_A7GW38 Cluster: Feruloyl-CoA synthetase; n=2; Campyloba... 37 0.30
UniRef50_A4VH78 Cluster: AMP-dependent synthetase and ligase; n=... 37 0.30
UniRef50_A4GHX3 Cluster: AMP-dependent synthetase and ligase; n=... 37 0.30
UniRef50_A7SBP2 Cluster: Predicted protein; n=3; Nematostella ve... 37 0.30
UniRef50_A1DJB5 Cluster: Hybrid NRPS/PKS enzyme, putative; n=2; ... 37 0.30
UniRef50_Q5QL42 Cluster: 4-chlorobenzoyl CoA ligase; n=1; Geobac... 37 0.40
UniRef50_Q3A567 Cluster: Acyl-CoA synthetase (AMP-forming)/AMP-a... 37 0.40
UniRef50_Q39U25 Cluster: AMP-dependent synthetase and ligase; n=... 37 0.40
UniRef50_Q9ZGA4 Cluster: FK506 polyketide synthase; n=4; cellula... 37 0.40
UniRef50_Q9FB27 Cluster: Peptide synthetase NRPS9-8; n=2; Actino... 37 0.40
UniRef50_Q1ZF62 Cluster: AMP-binding enzyme family protein; n=1;... 37 0.40
UniRef50_Q18RS6 Cluster: AMP-dependent synthetase and ligase; n=... 37 0.40
UniRef50_Q0RI70 Cluster: 2,3-dihydroxybenzoate-AMP ligase; n=2; ... 37 0.40
UniRef50_O30479 Cluster: PKS module 1; n=2; Streptomyces hygrosc... 37 0.40
UniRef50_A5V8K9 Cluster: AMP-dependent synthetase and ligase; n=... 37 0.40
UniRef50_A4PHM3 Cluster: Hybrid non ribosomal peptide synthetase... 37 0.40
UniRef50_A4FCX9 Cluster: Non-ribosomal peptide synthetase; n=1; ... 37 0.40
UniRef50_Q758Q5 Cluster: AEL302Wp; n=1; Eremothecium gossypii|Re... 37 0.40
UniRef50_A6S429 Cluster: Putative uncharacterized protein; n=1; ... 37 0.40
UniRef50_Q9HSM3 Cluster: Medium-chain acyl-CoA ligase; n=6; Halo... 37 0.40
UniRef50_Q9HQN8 Cluster: Long-chain fatty-acid-CoA ligase; n=1; ... 37 0.40
UniRef50_A5CFR5 Cluster: Acyl-CoA synthetase; n=1; uncultured ma... 36 0.53
UniRef50_Q8A422 Cluster: Long-chain-fatty-acid--CoA ligase; n=7;... 36 0.53
UniRef50_Q89W50 Cluster: Bll0843 protein; n=8; Proteobacteria|Re... 36 0.53
UniRef50_Q89IE2 Cluster: Bll5697 protein; n=3; Bradyrhizobium|Re... 36 0.53
UniRef50_Q5QL50 Cluster: Long-chain fatty-acid-CoA ligase; n=15;... 36 0.53
UniRef50_Q3M3K1 Cluster: Amino acid adenylation precursor; n=2; ... 36 0.53
UniRef50_Q39NV7 Cluster: AMP-dependent synthetase and ligase; n=... 36 0.53
UniRef50_Q2SJ71 Cluster: Acyl-CoA synthetases (AMP-forming)/AMP-... 36 0.53
UniRef50_Q2L0G0 Cluster: Putative fatty acid CoA ligase; n=1; Bo... 36 0.53
UniRef50_Q93N87 Cluster: Peptide synthetase; n=12; Bacteria|Rep:... 36 0.53
UniRef50_Q643C7 Cluster: Mannopeptimycin peptide synthetase MppA... 36 0.53
UniRef50_Q1AT30 Cluster: AMP-dependent synthetase and ligase; n=... 36 0.53
UniRef50_Q0B5J6 Cluster: AMP-dependent synthetase and ligase; n=... 36 0.53
UniRef50_A6Q2E0 Cluster: Long-chain fatty-acid-CoA ligase; n=8; ... 36 0.53
UniRef50_A2VNP9 Cluster: Fatty-acid-CoA ligase fadD13; n=7; Myco... 36 0.53
UniRef50_A1WCA3 Cluster: AMP-dependent synthetase and ligase; n=... 36 0.53
UniRef50_Q9P7T1 Cluster: Ferrichrome synthetase Sib1; n=3; Eukar... 36 0.53
UniRef50_Q4JHB4 Cluster: Acetoacyl-CoA synthetase; n=2; cellular... 36 0.53
UniRef50_Q0CFH7 Cluster: Putative uncharacterized protein; n=1; ... 36 0.53
UniRef50_Q3IR40 Cluster: Acyl-CoA synthetase II 1; n=2; Halobact... 36 0.53
UniRef50_Q04747 Cluster: Surfactin synthetase subunit 2; n=9; Ba... 36 0.53
UniRef50_UPI000051006A Cluster: COG1021: Peptide arylation enzym... 36 0.70
UniRef50_Q666G1 Cluster: Possible high molecular weight sideroph... 36 0.70
UniRef50_Q4ZT67 Cluster: Amino acid adenylation; n=15; Bacteria|... 36 0.70
UniRef50_Q39MZ8 Cluster: AMP-dependent synthetase and ligase; n=... 36 0.70
UniRef50_Q2T5W7 Cluster: Nonribosomal peptide synthetase, putati... 36 0.70
UniRef50_Q2JBJ2 Cluster: Amino acid adenylation; n=1; Frankia sp... 36 0.70
UniRef50_Q84DH9 Cluster: Peptide synthase; n=3; Streptomyces|Rep... 36 0.70
UniRef50_Q7WWU3 Cluster: Putative long-chain-fatty-acid-CoA liga... 36 0.70
UniRef50_Q0P7K1 Cluster: Putative hybrid non-ribosomal peptide-p... 36 0.70
UniRef50_Q0P7K0 Cluster: Putative non-ribosomal peptide synthase... 36 0.70
UniRef50_A6CKR2 Cluster: Long-chain fatty-acid-CoA ligase; n=1; ... 36 0.70
UniRef50_A3TZL9 Cluster: Putative acid--CoA ligase; n=1; Oceanic... 36 0.70
UniRef50_A0Z6F5 Cluster: Acyl-CoA synthetases (AMP-forming)/AMP-... 36 0.70
UniRef50_A0V6U3 Cluster: Amino acid adenylation domain; n=1; Del... 36 0.70
UniRef50_A0UUS2 Cluster: Amino acid adenylation domain; n=5; roo... 36 0.70
UniRef50_A0QHN3 Cluster: Syringomycin synthetase; n=3; Mycobacte... 36 0.70
UniRef50_A7RW72 Cluster: Predicted protein; n=1; Nematostella ve... 36 0.70
UniRef50_Q2GU14 Cluster: Putative uncharacterized protein; n=1; ... 36 0.70
UniRef50_UPI0000E478FC Cluster: PREDICTED: hypothetical protein;... 36 0.93
UniRef50_UPI00003932EB Cluster: COG1022: Long-chain acyl-CoA syn... 36 0.93
UniRef50_UPI000038E2BB Cluster: hypothetical protein Faci_030016... 36 0.93
UniRef50_Q9A8N2 Cluster: Long-chain-fatty-acid--CoA ligase; n=11... 36 0.93
UniRef50_Q8G488 Cluster: Possible long-chain-fatty acid CoA liga... 36 0.93
UniRef50_Q89VR5 Cluster: Bll0980 protein; n=8; Proteobacteria|Re... 36 0.93
UniRef50_Q7NDN7 Cluster: Glr4198 protein; n=1; Gloeobacter viola... 36 0.93
UniRef50_Q6D9Y3 Cluster: Enterobactin synthetase component F; n=... 36 0.93
UniRef50_Q5YPH6 Cluster: Putative non-ribosomal peptide syntheta... 36 0.93
UniRef50_Q5NW52 Cluster: DitJ-like CoA ligase (AMP forming), pos... 36 0.93
UniRef50_Q5KW69 Cluster: Long-chain fatty-acid-CoA ligase; n=1; ... 36 0.93
UniRef50_Q2Y7Z5 Cluster: Amino acid adenylation; n=2; Nitrosospi... 36 0.93
UniRef50_Q2JA66 Cluster: Amino acid adenylation; n=15; Bacteria|... 36 0.93
UniRef50_Q83Z53 Cluster: Putisolvin synthetase; n=3; Bacteria|Re... 36 0.93
UniRef50_Q2BIP8 Cluster: AMP-dependent synthetase and ligase; n=... 36 0.93
UniRef50_Q2B979 Cluster: Putative long-chain fatty-acid-CoA liga... 36 0.93
UniRef50_Q211M6 Cluster: Amino acid adenylation; n=1; Rhodopseud... 36 0.93
UniRef50_Q1IA18 Cluster: Putative non-ribosomal peptide syntheta... 36 0.93
UniRef50_Q0G5H5 Cluster: Acyl-CoA synthase; n=1; Fulvimarina pel... 36 0.93
UniRef50_Q0B1F7 Cluster: Amino acid adenylation domain; n=2; Bac... 36 0.93
UniRef50_A4F5C4 Cluster: AuaE protein; n=1; Stigmatella aurantia... 36 0.93
UniRef50_A3INW7 Cluster: Amino acid adenylation; n=1; Cyanothece... 36 0.93
UniRef50_A0H8Z8 Cluster: AMP-dependent synthetase and ligase; n=... 36 0.93
UniRef50_Q93H59 Cluster: Non-ribosimal peptide synthetase; n=1; ... 35 1.2
UniRef50_Q93H58 Cluster: Non-ribosomal peptide synthetase; n=1; ... 35 1.2
UniRef50_Q8PKR7 Cluster: ATP-dependent serine activating enzyme;... 35 1.2
UniRef50_Q7UYT8 Cluster: Saframycin Mx1 synthetase B; n=2; Bacte... 35 1.2
UniRef50_Q5YQK2 Cluster: Putative acyl-CoA synthetase; n=1; Noca... 35 1.2
UniRef50_Q5SKQ7 Cluster: Putative long-chain-fatty-acid--CoA lig... 35 1.2
UniRef50_Q5LV55 Cluster: Non-ribosomal peptide synthetase; n=5; ... 35 1.2
UniRef50_Q4ZT69 Cluster: Amino acid adenylation; n=8; cellular o... 35 1.2
UniRef50_Q5DQU4 Cluster: Acyl-CoA synthetase-like protein; n=1; ... 35 1.2
UniRef50_Q50JA3 Cluster: Nonribosomal peptide synthetase; n=2; C... 35 1.2
UniRef50_Q4C3C3 Cluster: Non-ribosomal peptide synthase:Amino ac... 35 1.2
UniRef50_Q1AV60 Cluster: Benzoate-CoA ligase family; n=3; Bacter... 35 1.2
UniRef50_Q120C7 Cluster: AMP-dependent synthetase and ligase; n=... 35 1.2
>UniRef50_UPI00015B60D2 Cluster: PREDICTED: similar to
ENSANGP00000011599; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to ENSANGP00000011599 - Nasonia
vitripennis
Length = 684
Score = 236 bits (577), Expect = 3e-61
Identities = 102/153 (66%), Positives = 129/153 (84%)
Frame = +2
Query: 128 YEKAQQRSLNDPEGFWGEVGSELEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDRHV 307
YE+A ++S+ +PE FW E+G +EW++PWDRVLD+SN PFTKW+VGGE + CYNAVDRHV
Sbjct: 51 YEEAFRKSIENPEEFWAEIGQCIEWSRPWDRVLDNSNEPFTKWYVGGETNACYNAVDRHV 110
Query: 308 VNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEA 487
G G + AL+HDSP+T+TVR++SY EL D+ SRLAG L LGVS+G RVLIYMPL+PE
Sbjct: 111 AAGLGSKTALIHDSPMTETVRRVSYAELLDRTSRLAGALAELGVSRGDRVLIYMPLIPET 170
Query: 488 IIAMLATNRIGAIHSVVFGGFAARELXTRIEHA 586
I+A+LAT R+GA+HSVVFGGFAA+EL TRI+HA
Sbjct: 171 IVAILATARLGAVHSVVFGGFAAKELATRIDHA 203
>UniRef50_Q9VC92 Cluster: CG6432-PA; n=7; cellular organisms|Rep:
CG6432-PA - Drosophila melanogaster (Fruit fly)
Length = 674
Score = 219 bits (536), Expect = 3e-56
Identities = 103/178 (57%), Positives = 133/178 (74%), Gaps = 6/178 (3%)
Frame = +2
Query: 68 QPFVSAADIE-CYNVCGXT-----PEYEKAQQRSLNDPEGFWGEVGSELEWTKPWDRVLD 229
+P SA + E +VCG P Y KA ++S+ +P FW E G+ L+W +PW++VLD
Sbjct: 2 EPGPSAVNYEGSESVCGMPVEAHDPLYLKAYRQSVQNPAAFWEEQGNLLDWDRPWEKVLD 61
Query: 230 DSNAPFTKWWVGGEMSVCYNAVDRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSR 409
+SN PFTKW+VGG ++ CYN++DRH++ GRG AL+HDSPLT T+R+++Y EL DQ+
Sbjct: 62 NSNPPFTKWYVGGYLNACYNSIDRHILAGRGSNVALIHDSPLTGTLRRVTYQELYDQIVL 121
Query: 410 LAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFAARELXTRIEH 583
LAG L LGV KG RV+IYMPL+PE IIAMLA R+GAIHSVVFGGFAAREL +RIEH
Sbjct: 122 LAGGLAKLGVVKGDRVVIYMPLIPETIIAMLAIVRLGAIHSVVFGGFAARELCSRIEH 179
>UniRef50_A7RH51 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 696
Score = 193 bits (470), Expect = 3e-48
Identities = 83/153 (54%), Positives = 116/153 (75%)
Frame = +2
Query: 128 YEKAQQRSLNDPEGFWGEVGSELEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDRHV 307
Y++A ++S+ DPEGFW +V ++W KP+ +V+D++ PFTKW+ GGE++ C+N +DRH+
Sbjct: 57 YDEAFKQSVEDPEGFWDDVAQGIDWYKPYTKVVDNATPPFTKWFPGGELNTCFNCLDRHI 116
Query: 308 VNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEA 487
NG G + AL++DSP++ + SY L+ V++ AG L +L V KG RV+IYMP+VP+A
Sbjct: 117 ENGIGGRIALIYDSPVSGKIEMYSYQNLQRLVAKFAGALNSLNVGKGDRVVIYMPMVPQA 176
Query: 488 IIAMLATNRIGAIHSVVFGGFAARELXTRIEHA 586
+IAMLA RIGAIHSVVFGGFAA EL RIEHA
Sbjct: 177 VIAMLACARIGAIHSVVFGGFAAAELARRIEHA 209
>UniRef50_UPI0000E4931E Cluster: PREDICTED: hypothetical protein,
partial; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: hypothetical protein, partial -
Strongylocentrotus purpuratus
Length = 353
Score = 188 bits (457), Expect = 1e-46
Identities = 82/152 (53%), Positives = 111/152 (73%)
Frame = +2
Query: 128 YEKAQQRSLNDPEGFWGEVGSELEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDRHV 307
Y + S+ PE FW E + W K WDRV+D + +P + W+VGGE+++CYNAVDRHV
Sbjct: 60 YPQVFADSITQPEEFWAEQAERVVWFKKWDRVMDLTQSPASNWFVGGELNMCYNAVDRHV 119
Query: 308 VNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEA 487
G G+Q A++HDSP+T +V KI+Y EL+D+VS+ A L GV G RVLIYMP++P+A
Sbjct: 120 DEGYGDQDAIIHDSPVTGSVTKITYKELQDEVSKFAAALVKSGVKYGDRVLIYMPMIPQA 179
Query: 488 IIAMLATNRIGAIHSVVFGGFAARELXTRIEH 583
++AMLA RIGAIH +VFGGFA++EL RI+H
Sbjct: 180 VMAMLACARIGAIHVLVFGGFASKELSVRIDH 211
>UniRef50_Q9H6R3 Cluster: CDNA: FLJ21963 fis, clone HEP05583; n=30;
cellular organisms|Rep: CDNA: FLJ21963 fis, clone
HEP05583 - Homo sapiens (Human)
Length = 686
Score = 188 bits (457), Expect = 1e-46
Identities = 76/157 (48%), Positives = 116/157 (73%)
Frame = +2
Query: 113 GXTPEYEKAQQRSLNDPEGFWGEVGSELEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNA 292
G EY+ S+ DPE FWG+ ++ W KPW + L++ ++P T+W+V G +++CYNA
Sbjct: 57 GSGSEYKTHFAASVTDPERFWGKAAEQISWYKPWTKTLENKHSPSTRWFVEGMLNICYNA 116
Query: 293 VDRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMP 472
VDRH+ NG+G++ A+++DSP+T+T +Y E+ +QVS+LAG L G+ KG V+IYMP
Sbjct: 117 VDRHIENGKGDKIAIIYDSPVTNTKATFTYKEVLEQVSKLAGVLVKHGIKKGDTVVIYMP 176
Query: 473 LVPEAIIAMLATNRIGAIHSVVFGGFAARELXTRIEH 583
++P+A+ MLA RIGAIHS++FGGFA++EL +RI+H
Sbjct: 177 MIPQAMYTMLACARIGAIHSLIFGGFASKELSSRIDH 213
>UniRef50_O67872 Cluster: Acetyl-coenzyme A synthetase; n=5;
cellular organisms|Rep: Acetyl-coenzyme A synthetase -
Aquifex aeolicus
Length = 510
Score = 159 bits (386), Expect = 4e-38
Identities = 78/154 (50%), Positives = 101/154 (65%)
Frame = +2
Query: 125 EYEKAQQRSLNDPEGFWGEVGSELEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDRH 304
+YEK + S+ D EGFW +V EL W K WD+VL+ N P+ KW+VG + ++ YN +DRH
Sbjct: 30 DYEKVYEESIKDREGFWAKVAEELHWFKKWDKVLE-WNFPYAKWFVGAKTNITYNCLDRH 88
Query: 305 VVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPE 484
V NG+ + A ++ D +KI+Y EL + V+R+A L +LGV KG RV IYMP E
Sbjct: 89 VQNGKRNKVAYIYVDE-NDNEKKITYGELLELVNRIANGLKSLGVKKGDRVSIYMPTTIE 147
Query: 485 AIIAMLATNRIGAIHSVVFGGFAARELXTRIEHA 586
AI MLA RIGAIHSVVF GF+ L TRIE A
Sbjct: 148 AIATMLACARIGAIHSVVFAGFSEGALRTRIEDA 181
>UniRef50_P28812 Cluster: Uncharacterized protein PA3568; n=81;
cellular organisms|Rep: Uncharacterized protein PA3568 -
Pseudomonas aeruginosa
Length = 628
Score = 153 bits (370), Expect = 4e-36
Identities = 73/153 (47%), Positives = 99/153 (64%)
Frame = +2
Query: 128 YEKAQQRSLNDPEGFWGEVGSELEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDRHV 307
Y + RS+ +P FW E L W + +L+ +W+ G ++ Y A+DR +
Sbjct: 3 YLQQHARSIAEPAAFWAEQARSLAWYQAPANILESLPDGTHRWFADGRLNSAYLALDRQI 62
Query: 308 VNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEA 487
GRGEQ AL++DSP+T T + SY L+D+V+RLAG L LGV KG RV+IYMP+VP+A
Sbjct: 63 EEGRGEQTALIYDSPVTGTQDRYSYLRLRDEVARLAGALRALGVGKGDRVIIYMPMVPQA 122
Query: 488 IIAMLATNRIGAIHSVVFGGFAARELXTRIEHA 586
+AMLA R+GA+HSVVFGGFA EL RI+ A
Sbjct: 123 AMAMLACARLGAVHSVVFGGFAPYELALRIDDA 155
>UniRef50_Q82EL5 Cluster: Acetyl-coenzyme A synthetase; n=28;
cellular organisms|Rep: Acetyl-coenzyme A synthetase -
Streptomyces avermitilis
Length = 652
Score = 150 bits (363), Expect = 3e-35
Identities = 73/151 (48%), Positives = 98/151 (64%)
Frame = +2
Query: 134 KAQQRSLNDPEGFWGEVGSELEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDRHVVN 313
+A +++ D GFW E L W LD SN PF KW+ G+++V YN VDRHV
Sbjct: 31 EAYEQAKADRLGFWAEQARRLTWATEPTETLDWSNPPFAKWFKDGKLNVAYNCVDRHVEA 90
Query: 314 GRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAII 493
G G++ A+ + D+ R I+Y ELKD+VS+ A LT LGV KG RV +Y+P++PEA++
Sbjct: 91 GHGDRVAIHFEGEPGDS-RAITYAELKDEVSKAANALTELGVQKGDRVAVYLPMIPEAVV 149
Query: 494 AMLATNRIGAIHSVVFGGFAARELXTRIEHA 586
AMLA RIGA HSVVFGGF+A + RI+ A
Sbjct: 150 AMLACARIGAAHSVVFGGFSADAIAARIKDA 180
>UniRef50_A5UUT7 Cluster: Acetate--CoA ligase; n=2; Roseiflexus|Rep:
Acetate--CoA ligase - Roseiflexus sp. RS-1
Length = 639
Score = 149 bits (361), Expect = 5e-35
Identities = 73/154 (47%), Positives = 98/154 (63%)
Frame = +2
Query: 125 EYEKAQQRSLNDPEGFWGEVGSELEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDRH 304
+YE +RS+ DP+GFW E L W +P+ VLDDS APF KW+VGG+ ++ YNA+DRH
Sbjct: 34 DYEAVYRRSIEDPQGFWAEAAQALHWFEPFHTVLDDSKAPFYKWFVGGKTNMAYNALDRH 93
Query: 305 VVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPE 484
V R + AL+ +S VR +Y +L V++ A L +LGV KG RV IY PE
Sbjct: 94 VQTWRKNKVALIWESE-DGEVRTYTYWQLYRDVNKFANVLKSLGVRKGDRVAIYTGRCPE 152
Query: 485 AIIAMLATNRIGAIHSVVFGGFAARELXTRIEHA 586
IAMLA RIGA+H+VV+GG + L +RI+ A
Sbjct: 153 QAIAMLACARIGAVHTVVYGGLSTEALRSRIDDA 186
>UniRef50_Q55404 Cluster: Acetyl-coenzyme A synthetase; n=89;
cellular organisms|Rep: Acetyl-coenzyme A synthetase -
Synechocystis sp. (strain PCC 6803)
Length = 653
Score = 149 bits (361), Expect = 5e-35
Identities = 73/155 (47%), Positives = 103/155 (66%), Gaps = 1/155 (0%)
Frame = +2
Query: 125 EYEKAQQRSLNDPEGFWGEVGS-ELEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDR 301
EYE+ R+ ++PE FWGE+ EL W K WD+VLD PF KW+VGG++++ +N +DR
Sbjct: 32 EYEQLYSRAASNPEKFWGELAEQELHWFKKWDQVLD-WQPPFAKWFVGGQLNISHNCLDR 90
Query: 302 HVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVP 481
H+ R + A++ + D+ R I+Y +L +V + A L +LGV KG RV IY+P++P
Sbjct: 91 HLTTWRRNKAAIIWEGEPGDS-RIITYAQLHREVCQFANALKSLGVQKGDRVAIYLPMIP 149
Query: 482 EAIIAMLATNRIGAIHSVVFGGFAARELXTRIEHA 586
EA I MLA +RIGA HSVVFGGF+A L R+ A
Sbjct: 150 EAAITMLACSRIGAPHSVVFGGFSAEALRDRLVDA 184
>UniRef50_P55912 Cluster: Propionate--CoA ligase; n=57;
Bacteria|Rep: Propionate--CoA ligase - Salmonella
typhimurium
Length = 628
Score = 149 bits (360), Expect = 6e-35
Identities = 69/153 (45%), Positives = 102/153 (66%)
Frame = +2
Query: 128 YEKAQQRSLNDPEGFWGEVGSELEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDRHV 307
+ + QRS+N+PE FW E ++W +P+ + LD S PF +W+ GG ++C+NAVDR
Sbjct: 3 FSEFYQRSINEPEAFWAEQARRIDWRQPFTQTLDHSRPPFARWFCGGTTNLCHNAVDRWR 62
Query: 308 VNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEA 487
+ + E AL+ S TD R ++++L D+V+ +A L +LGV +G RVL+YMP++ EA
Sbjct: 63 -DKQPEALALIAVSSETDEERTFTFSQLHDEVNIVAAMLLSLGVQRGDRVLVYMPMIAEA 121
Query: 488 IIAMLATNRIGAIHSVVFGGFAARELXTRIEHA 586
I +LA RIGAIHSVVFGGFA+ + RI+ A
Sbjct: 122 QITLLACARIGAIHSVVFGGFASHSVAARIDDA 154
>UniRef50_Q871W2 Cluster: Related to acetyl coenzyme A synthetase;
n=9; Pezizomycotina|Rep: Related to acetyl coenzyme A
synthetase - Neurospora crassa
Length = 694
Score = 146 bits (354), Expect = 3e-34
Identities = 72/162 (44%), Positives = 101/162 (62%), Gaps = 8/162 (4%)
Frame = +2
Query: 119 TPEYEKAQQRSLNDPEGFWGEVGSELEWTKPWDRVLDDSNAPFT--------KWWVGGEM 274
T ++AQ SL DPEGFWG +L W + VL + +W+ GE+
Sbjct: 2 THPQDEAQHLSLTDPEGFWGHQAEQLHWHRKPSAVLKRTTKDLKLGTSHSHWEWFPDGEI 61
Query: 275 SVCYNAVDRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGAR 454
S CYN +DRHV+ G G+Q A+++DS +T+T ++++Y +L +V AG L GV KG
Sbjct: 62 STCYNCLDRHVLAGHGDQPAILYDSSVTNTKQRLTYKQLLAEVETFAGVLREEGVKKGDV 121
Query: 455 VLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFAARELXTRIE 580
VL+YMP+VP +I +LA NR+GAIH+VVFGGFA+ L RIE
Sbjct: 122 VLVYMPMVPATLIGILAINRLGAIHAVVFGGFASTALAQRIE 163
>UniRef50_Q4WAZ5 Cluster: Acetate-CoA ligase, putative; n=1;
Aspergillus fumigatus|Rep: Acetate-CoA ligase, putative
- Aspergillus fumigatus (Sartorya fumigata)
Length = 721
Score = 144 bits (350), Expect = 1e-33
Identities = 69/158 (43%), Positives = 97/158 (61%), Gaps = 8/158 (5%)
Frame = +2
Query: 131 EKAQQRSLNDPEGFWGEVGSELEWTKPWDRVL--------DDSNAPFTKWWVGGEMSVCY 286
++ ++SL +P+ FW L W + D L D + P +W+ GGE+S CY
Sbjct: 8 DEVLRQSLQNPDEFWSRQAERLHWHRKPDTALRTTQKSLPDGTAHPMWEWFPGGEISTCY 67
Query: 287 NAVDRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIY 466
N VDRHV G G + A+ ++SP+T+T I+Y+ L +V LAG L GV KG V++Y
Sbjct: 68 NCVDRHVAAGNGHESAIYYNSPVTNTKETITYHTLLREVETLAGVLRETGVKKGDVVMLY 127
Query: 467 MPLVPEAIIAMLATNRIGAIHSVVFGGFAARELXTRIE 580
MP++P A+I MLA NR+GA+HSVVFGGFA L R+E
Sbjct: 128 MPMIPAALIGMLAVNRLGAVHSVVFGGFAPNALAQRVE 165
>UniRef50_Q5QYS0 Cluster: Propionyl-CoA synthetase; n=1; Idiomarina
loihiensis|Rep: Propionyl-CoA synthetase - Idiomarina
loihiensis
Length = 623
Score = 143 bits (347), Expect = 2e-33
Identities = 70/153 (45%), Positives = 93/153 (60%)
Frame = +2
Query: 128 YEKAQQRSLNDPEGFWGEVGSELEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDRHV 307
Y+ + DPEGFW E L W K W+ GE+++ Y A+D +
Sbjct: 4 YKNVYSEAQQDPEGFWLEQARRLNWFKTPKVAAQVKKNGLADWFPDGEVNISYLALDAQI 63
Query: 308 VNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEA 487
GRGEQ AL +DSP+T + ++N+L++QV+ A L GV KG RV+IY+P++P+A
Sbjct: 64 EAGRGEQVALYYDSPVTQSKANYTFNQLREQVACFAHVLKQQGVEKGDRVIIYLPMIPQA 123
Query: 488 IIAMLATNRIGAIHSVVFGGFAARELXTRIEHA 586
IAMLA RIGAIHSVVFGGFAA EL RI+ A
Sbjct: 124 AIAMLACARIGAIHSVVFGGFAAHELAVRIDDA 156
>UniRef50_A5WC66 Cluster: Propionate--CoA ligase; n=3;
Psychrobacter|Rep: Propionate--CoA ligase -
Psychrobacter sp. PRwf-1
Length = 670
Score = 143 bits (347), Expect = 2e-33
Identities = 83/187 (44%), Positives = 103/187 (55%), Gaps = 27/187 (14%)
Frame = +2
Query: 107 VCGXTPEYEKAQQRSLNDPEGFWGEVGSELEWTKPWDRVLDDSNAPFTKWWVGGEMSVCY 286
V T + + Q SL+DP FWG+ + W KP +VLDDSN PF KW+VGGE ++CY
Sbjct: 9 VTSATESFAELHQNSLSDPNAFWGKQAERIYWHKPPQQVLDDSNLPFAKWFVGGETNLCY 68
Query: 287 NAVDRHVVNGRGEQFALV--------------------------HDSPLTDTVR-KISYN 385
N VDRH + R EQ A V H TD + +++YN
Sbjct: 69 NCVDRH-LEARAEQDAFVWVSSEINQELLDNHPGVAEAFKALDNHVEFYTDYAKRRLTYN 127
Query: 386 ELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFAAREL 565
L +V+ A L LGV KG RV+IYMP++ EA AMLA RIGAIHSVVFGGFAA L
Sbjct: 128 RLYKEVNYFADVLQRLGVGKGDRVVIYMPMILEAAYAMLACTRIGAIHSVVFGGFAAHNL 187
Query: 566 XTRIEHA 586
R+ A
Sbjct: 188 AVRMSDA 194
>UniRef50_A2TC85 Cluster: AMP-dependent synthetase and ligase; n=4;
Bacteria|Rep: AMP-dependent synthetase and ligase -
Sphingomonas yanoikuyae
Length = 643
Score = 143 bits (346), Expect = 3e-33
Identities = 68/153 (44%), Positives = 94/153 (61%)
Frame = +2
Query: 128 YEKAQQRSLNDPEGFWGEVGSELEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDRHV 307
Y+ A + + N P+ FW E ++W + R D S W+ G ++ C+N +DRHV
Sbjct: 10 YDGAVRWAANRPDQFWLEAAKAIDWVENPPRAHDQSMG----WFPEGILNTCHNCLDRHV 65
Query: 308 VNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEA 487
GRG+ AL +DSP+T T+R +Y EL + R A L +LG KG RV++YMP++PE
Sbjct: 66 QAGRGDALALAYDSPVTGTIRHYTYRELLHETERTAAMLASLGAKKGDRVILYMPMIPET 125
Query: 488 IIAMLATNRIGAIHSVVFGGFAARELXTRIEHA 586
+ AMLA R+G IHSVVFGGFA EL RI+ A
Sbjct: 126 VFAMLACARLGVIHSVVFGGFAPPELAKRIDDA 158
>UniRef50_Q01L46 Cluster: H0502B11.5 protein; n=5;
Magnoliophyta|Rep: H0502B11.5 protein - Oryza sativa
(Rice)
Length = 747
Score = 136 bits (330), Expect = 3e-31
Identities = 71/172 (41%), Positives = 104/172 (60%), Gaps = 7/172 (4%)
Frame = +2
Query: 83 AADIECYNVCGXTPEYEKAQQRSLNDPEGFWGEVGSELEWTKPW--DRV----LDDSNAP 244
+AD + T +Y++ +RS++DP GFW E+ W W D V LD + P
Sbjct: 98 SADFASQALVSSTQQYQEMYRRSIDDPAGFWSEIAETFYWKHKWNPDEVCTENLDVTKGP 157
Query: 245 FT-KWWVGGEMSVCYNAVDRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGK 421
+W+ GG+ ++CYNAVDR+V G GE+ A+ + K++Y+EL ++V +LA
Sbjct: 158 IKIEWFKGGKTNICYNAVDRNVEAGDGEKIAMYWEGNEPGQDAKLTYSELLNKVCQLANY 217
Query: 422 LTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFAARELXTRI 577
L ++GV KG V+IY+P++ E IAMLA RIGA+HSVVF GF+A L RI
Sbjct: 218 LKSVGVGKGDAVVIYLPMLMELPIAMLACARIGAVHSVVFAGFSADALAQRI 269
>UniRef50_O93730 Cluster: Acetyl-coenzyme A synthetase; n=11;
Archaea|Rep: Acetyl-coenzyme A synthetase - Pyrobaculum
aerophilum
Length = 670
Score = 136 bits (330), Expect = 3e-31
Identities = 72/157 (45%), Positives = 98/157 (62%), Gaps = 7/157 (4%)
Frame = +2
Query: 128 YEKAQQRSLNDPEGFWGEVGSELEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDRHV 307
Y K ++++ + E FW V ELEW KPWD+VLD SN PF KW+VGG +++ Y AVDRHV
Sbjct: 33 YFKFHRQTVENLESFWESVAKELEWFKPWDKVLDASNPPFYKWFVGGRLNLSYLAVDRHV 92
Query: 308 VNGRGEQFAL------VHDSPLTDTVRKISYNELKDQVSRLAGKL-TTLGVSKGARVLIY 466
R + A+ V ++ RK++Y +L +V+R+A L GV KG ++ +Y
Sbjct: 93 KTWRKNKLAIEWEGEPVDENGYPTDRRKLTYYDLYREVNRVAYMLKQNFGVKKGDKITLY 152
Query: 467 MPLVPEAIIAMLATNRIGAIHSVVFGGFAARELXTRI 577
+P+VPE I MLA RIGAI SVVF GF+A L RI
Sbjct: 153 LPMVPELPITMLAAWRIGAITSVVFSGFSADALAERI 189
>UniRef50_A1CSK5 Cluster: Acyl-CoA synthetase, putative; n=7;
Pezizomycotina|Rep: Acyl-CoA synthetase, putative -
Aspergillus clavatus
Length = 716
Score = 136 bits (329), Expect = 4e-31
Identities = 73/154 (47%), Positives = 89/154 (57%), Gaps = 8/154 (5%)
Frame = +2
Query: 149 SLNDPEGFWGEVGSELEWTKPWDRVL--DDSNAP------FTKWWVGGEMSVCYNAVDRH 304
SL DPE FW ++L W KP R L P W+ GE+S YN VDRH
Sbjct: 12 SLQDPESFWSHHTAQLHWHKPPSRALVRQPKTLPSGVTHEHWAWFPDGEISTTYNCVDRH 71
Query: 305 VVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPE 484
V GRG+ A++ DS +T +Y L D+V LAG L GV KG V+IYMP++P
Sbjct: 72 VAAGRGDHAAIIWDSAVTGVQETYTYRRLLDEVEVLAGVLREEGVRKGDVVIIYMPMIPA 131
Query: 485 AIIAMLATNRIGAIHSVVFGGFAARELXTRIEHA 586
A+IA LA R+GAIHS VFGGFAA+ L RIE A
Sbjct: 132 ALIAALAITRLGAIHSAVFGGFAAKSLAQRIEAA 165
>UniRef50_Q0I9W4 Cluster: Acetate--CoA ligase; n=19; cellular
organisms|Rep: Acetate--CoA ligase - Synechococcus sp.
(strain CC9311)
Length = 656
Score = 136 bits (328), Expect = 5e-31
Identities = 67/151 (44%), Positives = 92/151 (60%), Gaps = 1/151 (0%)
Frame = +2
Query: 128 YEKAQQRSLNDPEGFWGEVGS-ELEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDRH 304
Y + + +DP+ FWG+ EL W +P+ VLD N PF +W+ GG ++ YN +DRH
Sbjct: 35 YRALAEAAKSDPDTFWGDAARRELHWFEPFHTVLDWDNPPFARWFEGGTTNLSYNCLDRH 94
Query: 305 VVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPE 484
+ + + AL+ + D VR +Y EL +V R A L +G+ KG V +YMP+VPE
Sbjct: 95 LNGPKASKTALIWEGEPGD-VRTFTYQELHAEVCRAANALKAIGIGKGDLVALYMPMVPE 153
Query: 485 AIIAMLATNRIGAIHSVVFGGFAARELXTRI 577
A IAMLA RIGA HSVVFGGF+A L R+
Sbjct: 154 AAIAMLACARIGAPHSVVFGGFSAEALRDRL 184
>UniRef50_Q22UI3 Cluster: AMP-binding enzyme family protein; n=6;
Oligohymenophorea|Rep: AMP-binding enzyme family protein
- Tetrahymena thermophila SB210
Length = 670
Score = 136 bits (328), Expect = 5e-31
Identities = 75/155 (48%), Positives = 100/155 (64%), Gaps = 4/155 (2%)
Frame = +2
Query: 128 YEKAQQRSLND--PEGFWGEVGSELEWTKPWDRVLDDSNAP--FTKWWVGGEMSVCYNAV 295
Y+ A +RS+N E +W E ++W K D +LD SN F +W+ ++++CYNAV
Sbjct: 35 YQIAFERSVNPLTREDYWREQTHFVDWFKRPDVILDKSNPNPGFWRWFKDSQVNMCYNAV 94
Query: 296 DRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPL 475
DRHV + AL SP R ++ EL+D V+RLAG LGV KG RV+IYMP+
Sbjct: 95 DRHVKQLHDKP-ALHWISPYEKIERTYTWAELQDNVARLAGVYQNLGVKKGDRVVIYMPM 153
Query: 476 VPEAIIAMLATNRIGAIHSVVFGGFAARELXTRIE 580
VPEA+ MLA R+GAIHSVVFGGFAA+EL +RI+
Sbjct: 154 VPEAVFGMLACARLGAIHSVVFGGFAAKELASRIK 188
>UniRef50_Q247U0 Cluster: AMP-binding enzyme family protein; n=1;
Tetrahymena thermophila SB210|Rep: AMP-binding enzyme
family protein - Tetrahymena thermophila SB210
Length = 691
Score = 135 bits (326), Expect = 8e-31
Identities = 68/156 (43%), Positives = 98/156 (62%), Gaps = 5/156 (3%)
Frame = +2
Query: 125 EYEKAQQRSLNDP--EGFWGEVGSELEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVD 298
+Y K S+ + E FW + L W K ++LD S PF +W+ GE+++CYNA+D
Sbjct: 5 QYNKLYNESVQEKSKEQFWQKAAENLHWFKKPSKILDKSQPPFYRWYSDGEINICYNAID 64
Query: 299 RHVVNGRGEQFALVHDSP-LTDTVRK--ISYNELKDQVSRLAGKLTTLGVSKGARVLIYM 469
RH G + AL+ +SP L +V+ +Y +L + V++LA L GV KG RV+IY+
Sbjct: 65 RHQAQ-HGNKTALIWESPSLKSSVQSETYTYKQLYENVAKLAWVLKQFGVKKGDRVIIYL 123
Query: 470 PLVPEAIIAMLATNRIGAIHSVVFGGFAARELXTRI 577
P VPEA+ +MLA +RIGAIH VV+GG+ A+EL RI
Sbjct: 124 PNVPEAVFSMLACSRIGAIHVVVYGGYPAKELAGRI 159
>UniRef50_Q869S4 Cluster: Similar to Bradyrhizobium japonicum.
Acetyl-coenzyme A synthetase; n=2; Dictyostelium
discoideum|Rep: Similar to Bradyrhizobium japonicum.
Acetyl-coenzyme A synthetase - Dictyostelium discoideum
(Slime mold)
Length = 655
Score = 133 bits (322), Expect = 3e-30
Identities = 68/155 (43%), Positives = 100/155 (64%), Gaps = 3/155 (1%)
Frame = +2
Query: 128 YEKAQQRSLNDPEGFWGEVGSE-LEWTKPWDRVLD-DSNAPFTKWWVGGEMSVCYNAVDR 301
YE+ + +L +P FW EV S+ + W K +++V D P +W+ GG ++ CYNA+D
Sbjct: 52 YEQDCEYALKEPIQFWDEVASKYVHWNKRYEKVYSGDEYNP--EWFKGGVLNACYNALDV 109
Query: 302 HVVNG-RGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLV 478
H + + A++H++P + K++Y EL D+V A L LGV KG RV+IYMP++
Sbjct: 110 HAKDPITKNRIAIIHETPSKNNTNKLTYGELWDEVCIFARGLHNLGVEKGDRVVIYMPMI 169
Query: 479 PEAIIAMLATNRIGAIHSVVFGGFAARELXTRIEH 583
+A+IAMLA R+GA HSVVFGGFA+ +L RIEH
Sbjct: 170 NQALIAMLACARLGATHSVVFGGFASPQLAQRIEH 204
>UniRef50_Q0JDG8 Cluster: Os04g0404800 protein; n=8; cellular
organisms|Rep: Os04g0404800 protein - Oryza sativa
subsp. japonica (Rice)
Length = 810
Score = 132 bits (320), Expect = 4e-30
Identities = 68/158 (43%), Positives = 99/158 (62%), Gaps = 7/158 (4%)
Frame = +2
Query: 125 EYEKAQQRSLNDPEGFWGEVGSELEWTKPW--DRV----LDDSNAPFT-KWWVGGEMSVC 283
+Y++ +RS++DP GFW E+ W W D V LD + P +W+ GG+ ++C
Sbjct: 220 QYQEMYRRSIDDPAGFWSEIAETFYWKHKWNPDEVCTENLDVTKGPIKIEWFKGGKTNIC 279
Query: 284 YNAVDRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLI 463
YNAVDR+V G GE+ A+ + K++Y+EL ++V +LA L ++GV KG V+I
Sbjct: 280 YNAVDRNVEAGDGEKIAMYWEGNEPGQDAKLTYSELLNKVCQLANYLKSVGVGKGDAVVI 339
Query: 464 YMPLVPEAIIAMLATNRIGAIHSVVFGGFAARELXTRI 577
Y+P++ E IAMLA RIGA+HSVVF GF+A L RI
Sbjct: 340 YLPMLMELPIAMLACARIGAVHSVVFAGFSADALAQRI 377
>UniRef50_Q8YJ48 Cluster: Acetyl-coenzyme A synthetase; n=48;
cellular organisms|Rep: Acetyl-coenzyme A synthetase -
Brucella melitensis
Length = 651
Score = 132 bits (319), Expect = 6e-30
Identities = 69/154 (44%), Positives = 98/154 (63%), Gaps = 4/154 (2%)
Frame = +2
Query: 128 YEKAQQRSLNDPEGFWGEVGSELEWTKPWDRVLD-DSNAPFT-KWWVGGEMSVCYNAVDR 301
Y + + S++DP+GFW + G ++W KP+ +V + D N T KW+ G +V YN +DR
Sbjct: 23 YLEWYEESVSDPDGFWAKHGRRIDWFKPFTKVKNTDFNGDVTIKWYEDGVTNVSYNCIDR 82
Query: 302 HVVNGRGEQFALVH--DSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPL 475
H+ RG++ A++ D+P D +KI+Y EL + V R+A L GV KG RV IY+P+
Sbjct: 83 HL-KSRGDKVAIIWEGDNPYID--KKITYRELYENVCRMANVLKKHGVKKGDRVTIYLPM 139
Query: 476 VPEAIIAMLATNRIGAIHSVVFGGFAARELXTRI 577
+PEA AMLA RIGA+HSVVF GF+ L RI
Sbjct: 140 IPEAAYAMLACARIGAVHSVVFAGFSPEALAGRI 173
>UniRef50_A7ATQ7 Cluster: Acetyl-CoA synthetase, putative; n=1;
Babesia bovis|Rep: Acetyl-CoA synthetase, putative -
Babesia bovis
Length = 703
Score = 131 bits (316), Expect = 1e-29
Identities = 69/156 (44%), Positives = 91/156 (58%), Gaps = 2/156 (1%)
Frame = +2
Query: 125 EYEKAQQRSLNDPEGFWGEVGS-ELEWTKPWDRVLD-DSNAPFTKWWVGGEMSVCYNAVD 298
EY++ +RSL DPEGFWG++ EL W P+ RV + D A W+VGG+++ C N VD
Sbjct: 69 EYKEMHRRSLEDPEGFWGDMAKKELRWIHPFSRVSEGDFTAADYMWFVGGKINACENCVD 128
Query: 299 RHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLV 478
R R A++ + V ++Y EL+ V R A L GV KG V +YMP +
Sbjct: 129 RWAEE-RPNDIAIIAEGDDPTKVTTVTYRELRHNVCRFANVLIDKGVRKGDVVTLYMPSI 187
Query: 479 PEAIIAMLATNRIGAIHSVVFGGFAARELXTRIEHA 586
PE AMLA RIGAIHSVVFGG++A + RI A
Sbjct: 188 PELAYAMLACARIGAIHSVVFGGYSAASIAERIRDA 223
>UniRef50_Q8KBY0 Cluster: Acetyl-coenzyme A synthetase; n=44;
cellular organisms|Rep: Acetyl-coenzyme A synthetase -
Chlorobium tepidum
Length = 659
Score = 130 bits (315), Expect = 2e-29
Identities = 60/151 (39%), Positives = 92/151 (60%)
Frame = +2
Query: 125 EYEKAQQRSLNDPEGFWGEVGSELEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDRH 304
+YEK + DP+ +WG++ + W K WD VL+ NAP+ KW+ GG ++ YN +D H
Sbjct: 41 QYEKLYADAAADPDKYWGDLAEQFHWFKKWDSVLE-WNAPYAKWFNGGTTNIAYNCLDVH 99
Query: 305 VVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPE 484
V + R + A++ + R ++Y EL QVS+ A L G+ G +V IYM +VPE
Sbjct: 100 VGSWRKNKAAIIWEGE-EGNERILTYGELHRQVSKFANVLKIAGIKPGDKVAIYMGMVPE 158
Query: 485 AIIAMLATNRIGAIHSVVFGGFAARELXTRI 577
+IA+LA R+GA+H+V+F GFAA + R+
Sbjct: 159 LVIAVLACARVGAVHNVIFAGFAAHAITERV 189
>UniRef50_Q4J9J7 Cluster: Acetyl-coenzyme A synthetase; n=4;
Sulfolobaceae|Rep: Acetyl-coenzyme A synthetase -
Sulfolobus acidocaldarius
Length = 654
Score = 130 bits (314), Expect = 2e-29
Identities = 61/154 (39%), Positives = 92/154 (59%), Gaps = 1/154 (0%)
Frame = +2
Query: 128 YEKAQQRSLNDPEGFWGEVGSEL-EWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDRH 304
Y+ ++S+ +P FW + L +W +PW + TKW+V G+++ YNA+DRH
Sbjct: 23 YKNIYKQSIEEPSKFWDRIAESLIDWFEPWKKTFVQEEGLLTKWFVEGKLNASYNAIDRH 82
Query: 305 VVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPE 484
+ R + A++ +S + R ++Y +L +V+R A L +GV KG RV IYMPL PE
Sbjct: 83 AFSNRKFKAAIIWESGKHER-RVLTYQDLYYEVNRWANALREIGVRKGDRVTIYMPLTPE 141
Query: 485 AIIAMLATNRIGAIHSVVFGGFAARELXTRIEHA 586
+I+MLA R+GAIH+VVF GF + L RI A
Sbjct: 142 GVISMLAVTRLGAIHNVVFAGFGVQALADRISDA 175
>UniRef50_Q89WV5 Cluster: Acetyl-coenzyme A synthetase; n=105;
Bacteria|Rep: Acetyl-coenzyme A synthetase -
Bradyrhizobium japonicum
Length = 648
Score = 129 bits (311), Expect = 5e-29
Identities = 66/154 (42%), Positives = 93/154 (60%), Gaps = 3/154 (1%)
Frame = +2
Query: 125 EYEKAQQRSLNDPEGFWGEVGSELEWTKPWDRVLDDSNAPFT---KWWVGGEMSVCYNAV 295
+Y++ RS++DP GFW E ++W K ++ + S AP KW+ G ++V +N +
Sbjct: 22 KYKEMYARSISDPNGFWAEQAKRIDWMKAPTKIENVSFAPGNVSIKWFEDGVLNVAHNCI 81
Query: 296 DRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPL 475
DRH+ + R Q A++ + R I+Y EL D+V R+A L T V KG RV IY+P+
Sbjct: 82 DRHL-HKRANQTAIIWEGDDPSQSRHITYKELHDEVCRMANILRTRNVKKGDRVTIYLPM 140
Query: 476 VPEAIIAMLATNRIGAIHSVVFGGFAARELXTRI 577
+PEA AMLA RIGAIHSVVF GF+ L RI
Sbjct: 141 IPEAAYAMLACARIGAIHSVVFAGFSPDSLAQRI 174
>UniRef50_A7HB74 Cluster: AMP-dependent synthetase and ligase; n=8;
cellular organisms|Rep: AMP-dependent synthetase and
ligase - Anaeromyxobacter sp. Fw109-5
Length = 650
Score = 128 bits (308), Expect = 1e-28
Identities = 74/179 (41%), Positives = 101/179 (56%)
Frame = +2
Query: 44 SSISALKKQPFVSAADIECYNVCGXTPEYEKAQQRSLNDPEGFWGEVGSELEWTKPWDRV 223
++ISAL K V AA + P +Q + DP+GFW E ++W KP+++V
Sbjct: 18 AAISALSKDDAVIAAPVWLAQRA-HVPNDAIERQFASQDPDGFWREKAKLVDWMKPFEQV 76
Query: 224 LDDSNAPFTKWWVGGEMSVCYNAVDRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQV 403
P +W+VGG+++ N +DRHV R + AL+ + +YN L +V
Sbjct: 77 TR-FEPPRHEWFVGGKLNATVNCIDRHVFGDRRLKAALIWVGEDGEE-HTYTYNRLYREV 134
Query: 404 SRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFAARELXTRIE 580
+R A L LGV KG RVL+YMPL PE II+MLA RIGAIHSVVF G + L +RIE
Sbjct: 135 NRFANALKKLGVRKGDRVLLYMPLTPEGIISMLACARIGAIHSVVFAGMGTQALRSRIE 193
>UniRef50_Q8ZV36 Cluster: Acetyl-coenzyme A synthetase; n=4;
Pyrobaculum|Rep: Acetyl-coenzyme A synthetase -
Pyrobaculum aerophilum
Length = 615
Score = 127 bits (307), Expect = 2e-28
Identities = 63/151 (41%), Positives = 94/151 (62%)
Frame = +2
Query: 125 EYEKAQQRSLNDPEGFWGEVGSELEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDRH 304
+Y + ++S++ PE FW V EL W K W++ LD SN PF +W+VGG ++ YN ++RH
Sbjct: 2 DYIEFWRKSISYPEIFWESVAKELFWKKKWEKPLDGSNPPFYRWFVGGVTNITYNILERH 61
Query: 305 VVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPE 484
+ + + +S L + I+Y EL +V++ A L GV +G RV IYMP++P+
Sbjct: 62 ---SKDKPAIIWFNSELKPHI--ITYGELSQEVNKWACLLKKAGVQQGDRVTIYMPMIPQ 116
Query: 485 AIIAMLATNRIGAIHSVVFGGFAARELXTRI 577
A AMLA +IGA+H+VVF GF+ R L RI
Sbjct: 117 AAYAMLAVAKIGAVHNVVFSGFSVRALHERI 147
>UniRef50_P27095 Cluster: Acetyl-coenzyme A synthetase; n=12;
cellular organisms|Rep: Acetyl-coenzyme A synthetase -
Methanothrix soehngenii
Length = 672
Score = 127 bits (307), Expect = 2e-28
Identities = 58/140 (41%), Positives = 89/140 (63%), Gaps = 2/140 (1%)
Frame = +2
Query: 170 FWGEVGSE-LEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDRHVVNGRGEQFALVH- 343
FW E+ ++W KP+ +V+DDS P+ W+ GGE+++ YNAVDRH + ++ A +
Sbjct: 64 FWDEMAKTYVDWHKPYTKVMDDSEMPYFHWFTGGEINITYNAVDRHAKGAKKDKVAYIWI 123
Query: 344 DSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGA 523
P V+KI+Y +L +V++ A L +LG+ KG RV IYMP++P+ IAMLA ++G
Sbjct: 124 PEPTDQPVQKITYGDLYKEVNKFANGLKSLGLKKGDRVSIYMPMIPQLPIAMLACAKLGV 183
Query: 524 IHSVVFGGFAARELXTRIEH 583
H VVF GF+++ L R H
Sbjct: 184 SHIVVFSGFSSKGLMDRAAH 203
>UniRef50_O25686 Cluster: Acetyl-coenzyme A synthetase; n=40;
Bacteria|Rep: Acetyl-coenzyme A synthetase -
Helicobacter pylori (Campylobacter pylori)
Length = 662
Score = 126 bits (305), Expect = 3e-28
Identities = 63/156 (40%), Positives = 96/156 (61%), Gaps = 2/156 (1%)
Frame = +2
Query: 125 EYEKAQQRSLNDPEGFWGEVGSE-LEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDR 301
EY+ + D E FWG++ + L W KP+D+VL+ NAPF KW+ G+++V YN +DR
Sbjct: 31 EYKDLVHEANEDYEHFWGDLAKQKLTWFKPFDKVLNSDNAPFFKWFENGKINVSYNCIDR 90
Query: 302 HVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTT-LGVSKGARVLIYMPLV 478
H+ + + + A++ + + D I+Y +L +V++ A L V KG RV+IYMP++
Sbjct: 91 HLKDKKNK-VAIIFEGEMGD-YNVITYRKLHSEVNKTANLLKNEFNVKKGDRVIIYMPMI 148
Query: 479 PEAIIAMLATNRIGAIHSVVFGGFAARELXTRIEHA 586
E++ MLA RIGAIHS+VF GF+ L RI A
Sbjct: 149 VESVYMMLACTRIGAIHSIVFAGFSPEALRDRINDA 184
>UniRef50_Q9PMD2 Cluster: Acetyl-coenzyme A synthetase; n=143;
cellular organisms|Rep: Acetyl-coenzyme A synthetase -
Campylobacter jejuni
Length = 657
Score = 126 bits (303), Expect = 5e-28
Identities = 66/152 (43%), Positives = 87/152 (57%), Gaps = 1/152 (0%)
Frame = +2
Query: 125 EYEKAQQRSLNDPEGFWGEVGSE-LEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDR 301
EY + D EGFW E +EW P+ RVL++ APF KW+ GG ++V Y +DR
Sbjct: 27 EYYDLCDEAKEDFEGFWKRQAFEKIEWFSPFSRVLNEDKAPFYKWFEGGTLNVSYQCLDR 86
Query: 302 HVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVP 481
H+ R + AL+ + + D +Y L + + A L GV KG RV+IYMP++P
Sbjct: 87 HMKTRRNKA-ALIFEGEMGD-YEVYTYRRLLHETCKAANLLKKFGVKKGDRVVIYMPMIP 144
Query: 482 EAIIAMLATNRIGAIHSVVFGGFAARELXTRI 577
E I MLA RIGAIHSVVFGGF+ L RI
Sbjct: 145 ETAIVMLACARIGAIHSVVFGGFSPEALRDRI 176
>UniRef50_Q8EYG2 Cluster: Acetyl-coenzyme A synthetase; n=76;
cellular organisms|Rep: Acetyl-coenzyme A synthetase -
Leptospira interrogans
Length = 661
Score = 124 bits (300), Expect = 1e-27
Identities = 61/153 (39%), Positives = 91/153 (59%), Gaps = 2/153 (1%)
Frame = +2
Query: 128 YEKAQQRSLNDPEGFWGEVGSELEWTKPWDRVL--DDSNAPFTKWWVGGEMSVCYNAVDR 301
Y+ + S+ +P FW + L W K W +VL D NA +W+ GG+++V YN +DR
Sbjct: 31 YKSLYKESIENPNKFWAREANRLIWFKKWTKVLSHDFKNAK-VEWFKGGKLNVSYNCLDR 89
Query: 302 HVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVP 481
H+ + AL+ + R ++Y ++ +V+R A L GV KG RVL+Y+P++P
Sbjct: 90 HISTPLKNKAALIWEGDNPTESRVLTYYDVYREVNRFANILKKFGVKKGDRVLVYLPMIP 149
Query: 482 EAIIAMLATNRIGAIHSVVFGGFAARELXTRIE 580
E I +LA RIGAIHSVVFGGF+ L +RI+
Sbjct: 150 ELAITILACTRIGAIHSVVFGGFSPEALQSRID 182
>UniRef50_Q7S7A6 Cluster: Putative uncharacterized protein
NCU01417.1; n=1; Neurospora crassa|Rep: Putative
uncharacterized protein NCU01417.1 - Neurospora crassa
Length = 709
Score = 122 bits (293), Expect = 8e-27
Identities = 71/186 (38%), Positives = 101/186 (54%), Gaps = 32/186 (17%)
Frame = +2
Query: 119 TPEYEKAQQRSLNDPEGFWGEVGSELEWTKPWDRVLDDSNAPFT--------KWWVGGEM 274
T ++AQ SL DPEGFWG +L W + VL + +W+ GE+
Sbjct: 56 THPQDEAQHLSLTDPEGFWGHQAEQLHWHRKPSAVLKRTTKDLKLGTSHSHWEWFPDGEI 115
Query: 275 SVCYNAVDRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGAR 454
S CYN +DRHV+ G G+Q A+++DS +T+T ++++Y +L +V AG L GV KG
Sbjct: 116 STCYNCLDRHVLAGHGDQPAILYDSSVTNTKQRLTYKQLLAEVETFAGVLREEGVKKGDV 175
Query: 455 VLIY------------------------MPLVPEAIIAMLATNRIGAIHSVVFGGFAARE 562
VL+Y +P+VP +I +LA NR+GAIH+VVFGGFA+
Sbjct: 176 VLVYSQFTQLRLSRVSTEPATDSLPIYIVPMVPATLIGILAINRLGAIHAVVFGGFASTA 235
Query: 563 LXTRIE 580
L RIE
Sbjct: 236 LAQRIE 241
>UniRef50_Q67QN3 Cluster: Acetyl-coenzyme A synthetase; n=6;
Bacteria|Rep: Acetyl-coenzyme A synthetase -
Symbiobacterium thermophilum
Length = 649
Score = 120 bits (288), Expect = 3e-26
Identities = 65/159 (40%), Positives = 97/159 (61%), Gaps = 3/159 (1%)
Frame = +2
Query: 110 CGXTPEYEKAQQRSLNDPEGFWGEVGSEL--EWTKPWDRVLD-DSNAPFTKWWVGGEMSV 280
CG E+ Q R+ DP FWGE ++ EW +P ++LD + AP+ W+ G M++
Sbjct: 25 CG-VGSLEELQARAAADPAWFWGEAVKDIGIEWYEPPRQILDLSAGAPWAAWFRGARMNL 83
Query: 281 CYNAVDRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVL 460
+ AVD+H+ N R Q A++++ TVR SY +L + +RLAG L LGV+KG RV
Sbjct: 84 AHEAVDKHLRN-RPHQLAVIYEGE-EGTVRTWSYRQLWAESNRLAGALRALGVAKGDRVG 141
Query: 461 IYMPLVPEAIIAMLATNRIGAIHSVVFGGFAARELXTRI 577
I +PL+PEA+ AM+A R+GAI + +F GFA +R+
Sbjct: 142 IMLPLIPEAVAAMMAVARLGAIFTPIFSGFAPAAAASRL 180
>UniRef50_Q01CP6 Cluster: Acyl-CoA synthetase; n=6; Eukaryota|Rep:
Acyl-CoA synthetase - Ostreococcus tauri
Length = 744
Score = 118 bits (285), Expect = 8e-26
Identities = 58/166 (34%), Positives = 92/166 (55%), Gaps = 11/166 (6%)
Frame = +2
Query: 113 GXTPEYEKAQQRSLNDPEGFWGEVGSELEWTKPWDRV----------LDDSNAP-FTKWW 259
G +Y RS+ +PE FW E+ EL W +D V D S + KW+
Sbjct: 80 GSMEQYRSMYNRSIKEPEMFWSEIAGELRWETAFDGVDKPEEVLEWNFDPSKGEVYVKWF 139
Query: 260 VGGEMSVCYNAVDRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGV 439
GG ++ +N +D + G G+ AL+ ++ R ++NEL+++VS + L G+
Sbjct: 140 AGGRTNMSFNCLDLQIERGLGDSPALIFEANDAVNSRIFTFNELREEVSTFSKFLVAQGI 199
Query: 440 SKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFAARELXTRI 577
KG RV++Y+P++P IAMLA RIGA+HS+VF G++A+ L R+
Sbjct: 200 GKGDRVIMYLPMIPMMPIAMLACARIGAVHSIVFAGYSAKSLAQRV 245
>UniRef50_Q978X5 Cluster: Acetyl-CoA synthetase; n=3; cellular
organisms|Rep: Acetyl-CoA synthetase - Thermoplasma
volcanium
Length = 641
Score = 118 bits (285), Expect = 8e-26
Identities = 55/153 (35%), Positives = 92/153 (60%)
Frame = +2
Query: 125 EYEKAQQRSLNDPEGFWGEVGSELEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDRH 304
E+++ + S NDP GFW + S+L W K WD V++ P ++ GG ++V N +DRH
Sbjct: 25 EFKRLLEFSKNDPNGFWESIASDLVWRKKWDTVME-GRLPEFSFFKGGYLNVAENLIDRH 83
Query: 305 VVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPE 484
+ G + AL+ +S T +Y L+ V++L+ L +LGV KG RV I++P +PE
Sbjct: 84 IEAGEANRAALIFESE-TGRSAVYTYAMLQSIVNKLSNALRSLGVKKGDRVSIFLPNIPE 142
Query: 485 AIIAMLATNRIGAIHSVVFGGFAARELXTRIEH 583
+ ++LA R+GA+ + +F GF+ + L R++H
Sbjct: 143 TLFSVLACYRVGAVFNTIFSGFSTQALENRLKH 175
>UniRef50_Q01574 Cluster: Acetyl-coenzyme A synthetase 1; n=40;
Fungi|Rep: Acetyl-coenzyme A synthetase 1 -
Saccharomyces cerevisiae (Baker's yeast)
Length = 713
Score = 118 bits (285), Expect = 8e-26
Identities = 62/159 (38%), Positives = 99/159 (62%), Gaps = 8/159 (5%)
Frame = +2
Query: 125 EYEKAQQRSLNDPEGFWGEVGSE-LEWTKPWDRVL---DDSNAPFTK---WWVGGEMSVC 283
+Y++ + S+ DP F+G ++ L W+KP+D+V + P + W++ G+++ C
Sbjct: 75 DYQRLHKESIEDPAKFFGSKATQFLNWSKPFDKVFIPDPKTGRPSFQNNAWFLNGQLNAC 134
Query: 284 YNAVDRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLT-TLGVSKGARVL 460
YN VDRH + ++ A++ + I+Y EL ++V ++A LT ++GV KG V
Sbjct: 135 YNCVDRHALKTPNKK-AIIFEGDEPGQGYSITYKELLEEVCQVAQVLTYSMGVRKGDTVA 193
Query: 461 IYMPLVPEAIIAMLATNRIGAIHSVVFGGFAARELXTRI 577
+YMP+VPEAII +LA +RIGAIHSVVF GF++ L RI
Sbjct: 194 VYMPMVPEAIITLLAISRIGAIHSVVFAGFSSNSLRDRI 232
>UniRef50_Q2RGI0 Cluster: Acetyl-coenzyme A synthetase; n=1;
Moorella thermoacetica ATCC 39073|Rep: Acetyl-coenzyme A
synthetase - Moorella thermoacetica (strain ATCC 39073)
Length = 329
Score = 118 bits (284), Expect = 1e-25
Identities = 59/138 (42%), Positives = 85/138 (61%)
Frame = +2
Query: 164 EGFWGEVGSELEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDRHVVNGRGEQFALVH 343
E FWG + L W + WDRVL+ + P W+ GG ++ YN +DRHV R + A++
Sbjct: 43 EEFWGREAARLHWFRRWDRVLE-WDYPLAWWFNGGTLNASYNCLDRHVETWRRNKAAIIW 101
Query: 344 DSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGA 523
+ D V ++Y +L +V++ A L +L V + RV IY+P++PE IAMLA RIGA
Sbjct: 102 EGEPGDAV-VLTYRDLYREVNKFAAVLRSLWVKRDDRVAIYLPMIPELPIAMLACARIGA 160
Query: 524 IHSVVFGGFAARELXTRI 577
+H+VVFGGF+A L RI
Sbjct: 161 VHNVVFGGFSAAALRDRI 178
>UniRef50_Q9HQU8 Cluster: Acetyl-CoA synthetase; n=11; root|Rep:
Acetyl-CoA synthetase - Halobacterium salinarium
(Halobacterium halobium)
Length = 667
Score = 116 bits (279), Expect = 4e-25
Identities = 59/139 (42%), Positives = 85/139 (61%), Gaps = 1/139 (0%)
Frame = +2
Query: 173 WGEVGSELEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDRHVVNGRGEQFALVH-DS 349
W + L+W P+D+VLDDSN PF +W+ GG ++ N +DRH+ + RG++ A+
Sbjct: 49 WTDAADLLDWETPYDQVLDDSNPPFYEWFPGGGLNASANCLDRHL-DERGDEAAIEWVGE 107
Query: 350 PLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIH 529
P + R +Y +L +V+ A L +GV + V +YMP+VPE IAMLA R+GA H
Sbjct: 108 PADEANRTYTYAQLHREVNEFAAGLREMGVGEDDIVTLYMPMVPELPIAMLACARLGAPH 167
Query: 530 SVVFGGFAARELXTRIEHA 586
SVVF GF+A L TR+ A
Sbjct: 168 SVVFAGFSADALSTRMNAA 186
>UniRef50_Q27549 Cluster: Acetyl-coenzyme A synthetase; n=7;
Apicomplexa|Rep: Acetyl-coenzyme A synthetase -
Cryptosporidium parvum
Length = 694
Score = 115 bits (276), Expect = 9e-25
Identities = 63/165 (38%), Positives = 94/165 (56%), Gaps = 3/165 (1%)
Frame = +2
Query: 101 YNVCGXTPEYEKAQQRSLNDPEGFWGEVG-SELEWTKPWDRVLDDSNAPFTK--WWVGGE 271
Y V G +Y++ ++S+ DPEGFW ++ EL W + + +V + W++ G+
Sbjct: 54 YRVDGID-KYKELYEQSIRDPEGFWSQMARKELRWLRDFTKVRSSGTCLQDRLAWFLNGK 112
Query: 272 MSVCYNAVDRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGA 451
++VC N VDR + AL+ + ++R ISY EL V ++A L G+ KG
Sbjct: 113 LNVCDNCVDRWA-EIQPNTTALIWEGDDPSSIRHISYIELFRNVCKMANVLKRFGIKKGD 171
Query: 452 RVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFAARELXTRIEHA 586
V IYMP++PE I MLA RIGA+H VVF GFAA+ L R+ +A
Sbjct: 172 SVGIYMPMIPETIYTMLACARIGAVHMVVFAGFAAQNLLERLVNA 216
>UniRef50_Q7RL40 Cluster: Acetate--CoA ligase-related; n=3;
Plasmodium (Vinckeia)|Rep: Acetate--CoA ligase-related -
Plasmodium yoelii yoelii
Length = 951
Score = 113 bits (273), Expect = 2e-24
Identities = 58/153 (37%), Positives = 92/153 (60%), Gaps = 2/153 (1%)
Frame = +2
Query: 125 EYEKAQQRSLNDPEGFWGEVG-SELEWTKPWDRV-LDDSNAPFTKWWVGGEMSVCYNAVD 298
EY+K + S+ +PE FWG++ + L W+K + + + + N W+V G+++ C N VD
Sbjct: 58 EYKKMYEESIKNPELFWGDMAKNNLRWSKLFTKTYIGNFNKGNVSWFVNGKINACDNCVD 117
Query: 299 RHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLV 478
R V + A++ + + +KISY +L ++V ++A L GV K V IY+P++
Sbjct: 118 RWVEK-HPNKTAIIWEKDTPNDYKKISYQKLLEKVCKIANLLKMYGVKKQDCVTIYLPMI 176
Query: 479 PEAIIAMLATNRIGAIHSVVFGGFAARELXTRI 577
PE I +MLA RIGAIH+VVF G++ R L RI
Sbjct: 177 PELIYSMLACARIGAIHNVVFAGYSTRSLSERI 209
>UniRef50_A6G1J4 Cluster: Acetate--CoA ligase; n=1; Plesiocystis
pacifica SIR-1|Rep: Acetate--CoA ligase - Plesiocystis
pacifica SIR-1
Length = 658
Score = 113 bits (271), Expect = 4e-24
Identities = 61/158 (38%), Positives = 90/158 (56%), Gaps = 6/158 (3%)
Frame = +2
Query: 122 PEYEKAQQRSLNDPEGFW-GEVGSELEWTKPWDRVLDDS-----NAPFTKWWVGGEMSVC 283
P Y + R DP G+W + + W K + L+ + P T W+ GE++V
Sbjct: 30 PAYREHWSRGEADPSGYWLAQTKQRVHWRKAPTQGLEGDCWSVCDGPIT-WFADGELNVT 88
Query: 284 YNAVDRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLI 463
+ +DR + RG++ A+V + VR+++Y EL +V R A L LG+ KG R +I
Sbjct: 89 ESCLDRQLAK-RGDKVAIVWEGDEPGDVRELTYKELHAEVCRCANALRELGLKKGERAII 147
Query: 464 YMPLVPEAIIAMLATNRIGAIHSVVFGGFAARELXTRI 577
YM +VPEA +AMLA R+GA+HSVVFGGF+A L R+
Sbjct: 148 YMGMVPEAAVAMLACARLGAVHSVVFGGFSAEALRDRV 185
>UniRef50_A2E702 Cluster: AMP-binding enzyme family protein; n=2;
Trichomonas vaginalis G3|Rep: AMP-binding enzyme family
protein - Trichomonas vaginalis G3
Length = 649
Score = 112 bits (270), Expect = 5e-24
Identities = 55/155 (35%), Positives = 94/155 (60%), Gaps = 2/155 (1%)
Frame = +2
Query: 128 YEKAQQRSLNDPEGFWGEVGSE-LEW-TKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDR 301
Y+K ++ ++ +P FW E + L+W + + ++ + W+ GG+++ CYNAVDR
Sbjct: 11 YKKMEKEAIENPTKFWSETAKDILKWESTDFKNIIGKIGDEKSCWFEGGKINTCYNAVDR 70
Query: 302 HVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVP 481
H + ++ AL+++ D R+++Y EL V ++A L + GV+KG+ V IY P+
Sbjct: 71 HAM-AHPDKVALLYEGNDIDDSRQMTYGELLQNVCKMANVLKSKGVTKGSHVAIYFPVSI 129
Query: 482 EAIIAMLATNRIGAIHSVVFGGFAARELXTRIEHA 586
E I++MLA RIGAIH+V+FG F+ L RI ++
Sbjct: 130 EGIVSMLACARIGAIHTVIFGAFSGDALSYRIHNS 164
>UniRef50_Q9NR19 Cluster: Acetyl-coenzyme A synthetase, cytoplasmic;
n=80; Eukaryota|Rep: Acetyl-coenzyme A synthetase,
cytoplasmic - Homo sapiens (Human)
Length = 701
Score = 112 bits (269), Expect = 7e-24
Identities = 57/157 (36%), Positives = 86/157 (54%), Gaps = 7/157 (4%)
Frame = +2
Query: 128 YEKAQQRSLNDPEGFWGEVGSELEWTKPWDRVLDDSNAPFTK------WWVGGEMSVCYN 289
Y + +RS+ +P FWG++ E W P N TK W G ++CYN
Sbjct: 47 YRELHRRSVEEPREFWGDIAKEFYWKTPCPGPFLRYNFDVTKGKIFIEWMKGATTNICYN 106
Query: 290 AVDRHVVNGR-GEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIY 466
+DR+V + G++ A + +I+Y++L QV + + L G+ KG RV IY
Sbjct: 107 VLDRNVHEKKLGDKVAFYWEGNEPGETTQITYHQLLVQVCQFSNVLRKQGIQKGDRVAIY 166
Query: 467 MPLVPEAIIAMLATNRIGAIHSVVFGGFAARELXTRI 577
MP++PE ++AMLA RIGA+HS+VF GF++ L RI
Sbjct: 167 MPMIPELVVAMLACARIGALHSIVFAGFSSESLCERI 203
>UniRef50_Q6LEZ6 Cluster: Acetyl-coenzyme a synthetase; n=3;
Plasmodium|Rep: Acetyl-coenzyme a synthetase -
Plasmodium falciparum (isolate 3D7)
Length = 997
Score = 111 bits (266), Expect = 2e-23
Identities = 58/152 (38%), Positives = 89/152 (58%), Gaps = 2/152 (1%)
Frame = +2
Query: 128 YEKAQQRSLNDPEGFWGEVG-SELEWTKPWDRV-LDDSNAPFTKWWVGGEMSVCYNAVDR 301
Y+ + S+N+PE FWG + + L W K + +V L + W+V G+++ C N VDR
Sbjct: 59 YKAMYEESINNPEAFWGNLAKNNLIWYKLFTKVFLGNFKKGNINWFVNGKINACENCVDR 118
Query: 302 HVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVP 481
V + AL+ + D +KI+Y +L ++ ++A L +GV K V IY+P++P
Sbjct: 119 WVEKDPNK-IALIWEQDCPDQYKKITYQKLLEKTCKVANLLKLIGVKKQDTVTIYLPMIP 177
Query: 482 EAIIAMLATNRIGAIHSVVFGGFAARELXTRI 577
E I +MLA RIGAIH+VVF G++A L RI
Sbjct: 178 ELIYSMLACVRIGAIHNVVFAGYSAASLSDRI 209
>UniRef50_Q81Q80 Cluster: Acetoacetyl-CoA synthase, putative; n=10;
Bacillus|Rep: Acetoacetyl-CoA synthase, putative -
Bacillus anthracis
Length = 646
Score = 110 bits (264), Expect = 3e-23
Identities = 60/158 (37%), Positives = 89/158 (56%), Gaps = 4/158 (2%)
Frame = +2
Query: 125 EYEKAQQRSLNDPEGFWGEVGSEL--EWTKPWDRVLDDSNA-PFTKWWVGGEMSVCYNAV 295
+YE +S+ + FWGE + +W KP+ VLD N PF +W+ GG +V + +
Sbjct: 29 DYETFYNKSIEETAWFWGEAEKVVGYQWMKPYTEVLDLQNGTPFAQWYNGGTCNVVESVL 88
Query: 296 DRHVVNGRGE-QFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMP 472
R + + Q AL ++ T + +Y EL VSR A L G+ KG RV IYMP
Sbjct: 89 SRWLADDETRTQPALQYEGE-NGTSKSFTYEELDSWVSRAANGLKHAGIEKGDRVTIYMP 147
Query: 473 LVPEAIIAMLATNRIGAIHSVVFGGFAARELXTRIEHA 586
++PE ++AMLA +IGAI S +F GFA+ + TR++ A
Sbjct: 148 MIPETVVAMLAVMKIGAIISPIFSGFASDAVMTRVQAA 185
>UniRef50_Q9NUB1 Cluster: Acetyl-coenzyme A synthetase 2-like,
mitochondrial precursor; n=35; Deuterostomia|Rep:
Acetyl-coenzyme A synthetase 2-like, mitochondrial
precursor - Homo sapiens (Human)
Length = 689
Score = 109 bits (263), Expect = 4e-23
Identities = 60/155 (38%), Positives = 86/155 (55%), Gaps = 2/155 (1%)
Frame = +2
Query: 128 YEKAQQRSLNDPEGFWGEVGSE-LEWTKPWDRVLD-DSNAPFTKWWVGGEMSVCYNAVDR 301
Y ++ +P FWG + + L W P+ V D D + W++GG+++V N +D+
Sbjct: 58 YPALSAQAAREPAAFWGPLARDTLVWDTPYHTVWDCDFSTGKIGWFLGGQLNVSVNCLDQ 117
Query: 302 HVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVP 481
HV E AL+ + T +I+Y EL + RLA L GV +G RV IYMP+ P
Sbjct: 118 HVRKSP-ESVALIWERDEPGTEVRITYRELLETTCRLANTLKRHGVHRGDRVAIYMPVSP 176
Query: 482 EAIIAMLATNRIGAIHSVVFGGFAARELXTRIEHA 586
A+ AMLA RIGA+H+V+F GF+A L RI A
Sbjct: 177 LAVAAMLACARIGAVHTVIFAGFSAESLAGRINDA 211
>UniRef50_Q5BYW0 Cluster: SJCHGC03435 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC03435 protein - Schistosoma
japonicum (Blood fluke)
Length = 206
Score = 109 bits (261), Expect = 6e-23
Identities = 59/162 (36%), Positives = 96/162 (59%), Gaps = 8/162 (4%)
Frame = +2
Query: 125 EYEKAQQRSLNDPEGFWGEVGSELEWTKP---WDRVL----DDSNAP-FTKWWVGGEMSV 280
E++ ++L++P+ FW + +W KP +++ L D P F KW+ G ++
Sbjct: 21 EHKWLSDKALSNPKEFWLGYAMKFDW-KPHPSFEKCLSYNFDCRMGPIFIKWFEDGYTNI 79
Query: 281 CYNAVDRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVL 460
CYN +DR++ G G++ A++ + + +++Y+E+ +V R+ L G+ KG V
Sbjct: 80 CYNILDRNIDRGFGDKVAILWEGNDPNDTTQLTYSEMLFKVKRIGKMLENFGIRKGDCVA 139
Query: 461 IYMPLVPEAIIAMLATNRIGAIHSVVFGGFAARELXTRIEHA 586
IYMP+VPE I+ MLA RIGA+HSV+FGGF+A L RI A
Sbjct: 140 IYMPMVPELIMTMLACARIGAVHSVIFGGFSACALAGRIMDA 181
>UniRef50_UPI0000382F9A Cluster: COG0365: Acyl-coenzyme A
synthetases/AMP-(fatty) acid ligases; n=1;
Magnetospirillum magnetotacticum MS-1|Rep: COG0365:
Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases -
Magnetospirillum magnetotacticum MS-1
Length = 82
Score = 108 bits (260), Expect = 8e-23
Identities = 44/70 (62%), Positives = 56/70 (80%)
Frame = +2
Query: 191 ELEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDRHVVNGRGEQFALVHDSPLTDTVR 370
E+ W K WD+VLDDS PF +W+VG E + CYNA+DRHV GRG Q A+++DSP+T+T R
Sbjct: 6 EIHWYKTWDKVLDDSKKPFYRWFVGAETNTCYNAIDRHVEQGRGAQTAIIYDSPVTNTKR 65
Query: 371 KISYNELKDQ 400
KISY+ELKDQ
Sbjct: 66 KISYDELKDQ 75
>UniRef50_Q127M4 Cluster: AMP-dependent synthetase and ligase; n=4;
cellular organisms|Rep: AMP-dependent synthetase and
ligase - Polaromonas sp. (strain JS666 / ATCC BAA-500)
Length = 688
Score = 105 bits (252), Expect = 8e-22
Identities = 54/140 (38%), Positives = 78/140 (55%), Gaps = 1/140 (0%)
Frame = +2
Query: 161 PEGFWGEVGSELEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDRHVVNGRGEQFALV 340
PE F E L+W K W+ LD SN PF +W+VGG+++ CYN VDRH+ + +
Sbjct: 63 PECF-KEFADLLDWYKYWETTLDTSNPPFWRWFVGGKINACYNCVDRHLGQHKNKTAIHF 121
Query: 341 HDSPLTDTVRKISYNELKDQVSRLAGKLTTL-GVSKGARVLIYMPLVPEAIIAMLATNRI 517
P + + ++Y EL +V+ A L G+ G RV ++MP+V E I MLA R+
Sbjct: 122 VPEPEDEAPQHLTYQELFVRVNEFAALLRDFCGLKAGDRVTLHMPMVAELPITMLACARL 181
Query: 518 GAIHSVVFGGFAARELXTRI 577
G IHS VF GF+ + R+
Sbjct: 182 GVIHSQVFSGFSGKACADRV 201
>UniRef50_Q557A3 Cluster: Putative uncharacterized protein; n=2;
Dictyostelium discoideum|Rep: Putative uncharacterized
protein - Dictyostelium discoideum AX4
Length = 709
Score = 104 bits (249), Expect = 2e-21
Identities = 55/153 (35%), Positives = 84/153 (54%), Gaps = 2/153 (1%)
Frame = +2
Query: 128 YEKAQQRSLNDPEGFWGEVGSE-LEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDRH 304
Y+K S N P FW EV + W + +D+V + W+ GGE++ CYN +D H
Sbjct: 10 YDKDFSFSNNQPIEFWDEVAKNFVHWDRMYDKVYSGDEI-YPDWFKGGELNTCYNVLDIH 68
Query: 305 VVN-GRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVP 481
+ N + +Q AL+++ P K++Y +L ++V + L L VSK V+IYM
Sbjct: 69 IKNPAKRDQDALIYECPFLKKTIKLTYYQLYEKVCEFSRALLNLNVSKNDNVIIYMANTV 128
Query: 482 EAIIAMLATNRIGAIHSVVFGGFAARELXTRIE 580
EA IAML+ RIGA + +F G++ + L RIE
Sbjct: 129 EAPIAMLSCARIGATYCTLFDGYSVKSLIDRIE 161
>UniRef50_A5K2B0 Cluster: Acetyl-CoA synthetase, putative; n=1;
Plasmodium vivax|Rep: Acetyl-CoA synthetase, putative -
Plasmodium vivax
Length = 1053
Score = 104 bits (249), Expect = 2e-21
Identities = 53/152 (34%), Positives = 88/152 (57%), Gaps = 2/152 (1%)
Frame = +2
Query: 128 YEKAQQRSLNDPEGFWGEVG-SELEWTKPWDRV-LDDSNAPFTKWWVGGEMSVCYNAVDR 301
Y++ + S+N+PE FWG + + + W K + +V + + W+V G+++ C N VDR
Sbjct: 59 YKEMYEESINNPELFWGNIAKNSVRWFKLFTKVYIGNFKKGNISWFVNGKINACDNCVDR 118
Query: 302 HVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVP 481
V + A++ + + +KI+Y +L ++ ++A L GV K V IY+P++P
Sbjct: 119 WVEK-HPNKIAIIWEKDTPNDFKKITYQKLLERTCKIANLLKMYGVKKQDVVTIYLPMIP 177
Query: 482 EAIIAMLATNRIGAIHSVVFGGFAARELXTRI 577
E + MLA RIGAIH+VVF G++A L RI
Sbjct: 178 EIVYTMLACARIGAIHNVVFAGYSAGSLCDRI 209
>UniRef50_Q8SRZ9 Cluster: ACETYLCOENZYME A SYNTHETASE; n=1;
Encephalitozoon cuniculi|Rep: ACETYLCOENZYME A
SYNTHETASE - Encephalitozoon cuniculi
Length = 632
Score = 104 bits (249), Expect = 2e-21
Identities = 52/152 (34%), Positives = 91/152 (59%), Gaps = 1/152 (0%)
Frame = +2
Query: 125 EYEKAQQRSLNDPEGFWGEVGSEL-EWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDR 301
EYE +RS+ D EGFWGE L +W + +DRV ++ + ++W+ GG ++ CYN VDR
Sbjct: 5 EYEGLYKRSIEDKEGFWGEQAKVLLKWDRMFDRVYNN-DFENSRWFEGGMLNACYNCVDR 63
Query: 302 HVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVP 481
H ++ A++++ ++V ++ ++ D+V R+ L G+ KG V +YM + P
Sbjct: 64 HAACSP-DKVAVIYEGNDGESVY-YTFKDVLDEVIRICTILKDEGLEKGDTVAMYMAMSP 121
Query: 482 EAIIAMLATNRIGAIHSVVFGGFAARELXTRI 577
A+ + LA R+G +H+ +FGGF+A + R+
Sbjct: 122 YAVFSALACARLGLVHNAIFGGFSASSVALRL 153
>UniRef50_Q86AI5 Cluster: Similar to Bradyrhizobium japonicum.
Acetyl-coenzyme A synthetase; n=2; Dictyostelium
discoideum|Rep: Similar to Bradyrhizobium japonicum.
Acetyl-coenzyme A synthetase - Dictyostelium discoideum
(Slime mold)
Length = 606
Score = 103 bits (248), Expect = 2e-21
Identities = 56/153 (36%), Positives = 84/153 (54%), Gaps = 2/153 (1%)
Frame = +2
Query: 128 YEKAQQRSLNDPEGFWGEVGSELE-WTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDRH 304
YE + N P FW EV +L W + +D+V + W+ GGE++ CYN +D H
Sbjct: 6 YENEIDLANNRPIEFWDEVAKDLVYWDRMYDKVYSGDEI-YPDWFKGGELNTCYNVLDIH 64
Query: 305 VVNGRG-EQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVP 481
+ N +Q AL+++ P + K++Y + ++V + L L +SK VLIYM
Sbjct: 65 IKNPETRDQTALIYECPFLNKNIKLTYYQFYEKVCEFSRVLLNLNISKNDNVLIYMSNTI 124
Query: 482 EAIIAMLATNRIGAIHSVVFGGFAARELXTRIE 580
EA IAML+ RIGA H V+F G++ + L RIE
Sbjct: 125 EAPIAMLSCARIGATHCVLFDGYSVKSLIDRIE 157
>UniRef50_Q75JX6 Cluster: Similar to Vibrio cholerae. PrpE protein;
n=21; Dictyostelium discoideum|Rep: Similar to Vibrio
cholerae. PrpE protein - Dictyostelium discoideum (Slime
mold)
Length = 658
Score = 103 bits (248), Expect = 2e-21
Identities = 55/154 (35%), Positives = 87/154 (56%), Gaps = 2/154 (1%)
Frame = +2
Query: 125 EYEKAQQRSLNDPEGFWGEVGSEL-EWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDR 301
+YE + S +P FW EV + W K +D+V S+ + W+ GGE++ CYN +D+
Sbjct: 9 DYENDCKYSQINPISFWDEVAKKYAHWDKMYDKVYS-SDGMYPDWFKGGELNTCYNVLDK 67
Query: 302 HVVN-GRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLV 478
HV N + +Q AL+++ P K++Y +L ++V + L L +SK VLIYM
Sbjct: 68 HVKNPSKRDQDALIYECPFIKKTIKLTYFQLYEKVCEFSRVLLNLNISKNDNVLIYMANT 127
Query: 479 PEAIIAMLATNRIGAIHSVVFGGFAARELXTRIE 580
E IIA+L+ RIGA V++ G+ + L RI+
Sbjct: 128 LEPIIALLSCARIGATFIVLYDGYPVKSLIDRID 161
>UniRef50_A1S0M6 Cluster: AMP-dependent synthetase and ligase; n=1;
Thermofilum pendens Hrk 5|Rep: AMP-dependent synthetase
and ligase - Thermofilum pendens (strain Hrk 5)
Length = 588
Score = 103 bits (247), Expect = 3e-21
Identities = 56/151 (37%), Positives = 80/151 (52%)
Frame = +2
Query: 125 EYEKAQQRSLNDPEGFWGEVGSELEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDRH 304
EY + + S+ D GFW L W KPW+RV++ AP +W+ GGE+S N V RH
Sbjct: 23 EYRRVYRESVEDVYGFWSSYARLLLWRKPWERVVE-GEAPRVRWFAGGELSPYENVVSRH 81
Query: 305 VVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPE 484
+ A++++S D ++Y L R+AG L ++GV +G V +Y P PE
Sbjct: 82 RGTPVWRKVAVLYESESGDA-EVLTYEGLDALAGRIAGWLESVGVGRGDWVTVYSPPNPE 140
Query: 485 AIIAMLATNRIGAIHSVVFGGFAARELXTRI 577
++ MLA R+GA VF GF EL RI
Sbjct: 141 SLAFMLAAMRVGAPFEPVFTGFGYYELAKRI 171
>UniRef50_Q54YU1 Cluster: Putative uncharacterized protein; n=1;
Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein - Dictyostelium discoideum AX4
Length = 661
Score = 103 bits (246), Expect = 4e-21
Identities = 47/120 (39%), Positives = 76/120 (63%)
Frame = +2
Query: 206 KPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDRHVVNGRGEQFALVHDSPLTDTVRKISYN 385
K ++ + + +N +W+ GG ++ CYNA+D+H+VNG GE+ A VH+ P +I+Y
Sbjct: 7 KEYENIYNSNN---NEWFSGGLLNACYNALDKHIVNGGGEEIAFVHEIPSKQISTQITYK 63
Query: 386 ELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFAAREL 565
+L D+V + + L LG+ KG V+IYM E II+ L+ RIGA H+++FGG+ + L
Sbjct: 64 QLFDKVCKFSRSLKNLGIKKGDIVIIYMHNSIELIISALSCCRIGATHNIIFGGYTQKGL 123
>UniRef50_Q97WQ9 Cluster: Acetyl-CoA synthetase; n=3;
Sulfolobus|Rep: Acetyl-CoA synthetase - Sulfolobus
solfataricus
Length = 622
Score = 101 bits (241), Expect = 2e-20
Identities = 48/142 (33%), Positives = 86/142 (60%)
Frame = +2
Query: 149 SLNDPEGFWGEVGSELEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDRHVVNGRGEQ 328
S+ +PE FW + + + W + +++L+ P+ KW+VGG +++ YNA+DRH+ + + ++
Sbjct: 18 SMENPEAFWRDKANYVSWFRQPEKILE-GEPPYEKWFVGGTLNISYNAIDRHLPDKK-DK 75
Query: 329 FALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLAT 508
A + D+ R IS+ +L +V++ A L+ LGV KG V + MP +PEA+ LAT
Sbjct: 76 VAFYWTNERLDSFRSISFQDLYQEVNKAAYVLSELGVKKGDTVSMLMPNIPEAVYFSLAT 135
Query: 509 NRIGAIHSVVFGGFAARELXTR 574
+R+GAI + + G + + R
Sbjct: 136 HRLGAILIIHYVGLSEETVAYR 157
>UniRef50_Q4PHQ0 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 1162
Score = 100 bits (240), Expect = 2e-20
Identities = 70/185 (37%), Positives = 95/185 (51%), Gaps = 32/185 (17%)
Frame = +2
Query: 122 PEYEKAQQRSLNDPEGFWGEVGSELEWTKPWDRVL---DDSNAPFTK-----WWVGGEMS 277
P+ E Q++S+ + + FW + + W KP + NA + W+ +++
Sbjct: 4 PQVE-IQRQSIENRDDFWLKAARSVHWHKPPTVAYGPTSNRNAAYLDPQGQTWFPDAQLN 62
Query: 278 VCYNAVDRHV---------------------VNGRGEQFALVHDSPL---TDTVRKISYN 385
CY+AVDRHV + + A H SPL T R ++Y
Sbjct: 63 TCYSAVDRHVYAPAHAAAAPITVSPDTPHLALAPTAHKVAFHHVSPLSFQTHQSRSVTYY 122
Query: 386 ELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFAAREL 565
EL QV +AG L GVSKG V+IYMP+VPE IAMLA RIGA+HSVVFGGFA +EL
Sbjct: 123 ELLQQVQIVAGILRHKGVSKGDAVVIYMPMVPETSIAMLACARIGAVHSVVFGGFAPKEL 182
Query: 566 XTRIE 580
R+E
Sbjct: 183 AKRVE 187
>UniRef50_Q93LL2 Cluster: Acetyl-coenzyme A synthetase; n=165;
cellular organisms|Rep: Acetyl-coenzyme A synthetase -
Nostoc linckia
Length = 337
Score = 100 bits (240), Expect = 2e-20
Identities = 47/110 (42%), Positives = 73/110 (66%)
Frame = +2
Query: 251 KWWVGGEMSVCYNAVDRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTT 430
KW+ G ++V + +DRH+ RG+Q A++ + + K++Y EL +V +LA +
Sbjct: 8 KWFEDGVLNVTESCLDRHLAT-RGDQVAIIWEGDDPNADSKVTYRELHARVCQLANAMRG 66
Query: 431 LGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFAARELXTRIE 580
+GV KG RV IY+P++ EA +AMLA RIGA+HS+VFGGF+ L +RI+
Sbjct: 67 MGVQKGDRVCIYLPMIEEAAVAMLACARIGAVHSIVFGGFSPDSLSSRIQ 116
>UniRef50_Q5FTV0 Cluster: Acetyl-coenzyme A synthetase; n=1;
Gluconobacter oxydans|Rep: Acetyl-coenzyme A synthetase
- Gluconobacter oxydans (Gluconobacter suboxydans)
Length = 635
Score = 99 bits (238), Expect = 4e-20
Identities = 59/155 (38%), Positives = 84/155 (54%), Gaps = 2/155 (1%)
Frame = +2
Query: 119 TP-EYEKAQQRSLNDPEGFWGEVGSELEW-TKPWDRVLDDSNAPFTKWWVGGEMSVCYNA 292
TP +Y +++ PE +W L W T P ++ W+ GG ++ N
Sbjct: 13 TPADYGHLVEQATVAPEHYWERESRRLNWSTTP-----GQAHCTERGWFPGGVLNASVNC 67
Query: 293 VDRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMP 472
+DRH+ RG+Q ALV + TD V +Y L ++V R+A L GV G RV I++P
Sbjct: 68 LDRHLET-RGDQNALVWQAEETDRVVTFTYRTLHERVCRMANVLREQGVQTGDRVAIHLP 126
Query: 473 LVPEAIIAMLATNRIGAIHSVVFGGFAARELXTRI 577
VPE +IAMLA RIGAIH V+FGGF+ + R+
Sbjct: 127 SVPEGLIAMLACARIGAIHVVLFGGFSPEAIADRL 161
>UniRef50_Q6U666 Cluster: Putative uncharacterized protein; n=1;
Klebsiella pneumoniae|Rep: Putative uncharacterized
protein - Klebsiella pneumoniae
Length = 579
Score = 99.1 bits (236), Expect = 7e-20
Identities = 54/147 (36%), Positives = 82/147 (55%), Gaps = 3/147 (2%)
Frame = +2
Query: 146 RSLNDP--EGFWGEVGSELEWTKPWDRVLDD-SNAPFTKWWVGGEMSVCYNAVDRHVVNG 316
+S +DP FW E + L W + V++ +P +W+ GG ++ +NA+DRH+
Sbjct: 28 QSEHDPFLRDFWREESARLYWETDFTEVVESLDGSPRCRWFTGGRTNLSFNALDRHLAE- 86
Query: 317 RGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIA 496
+GE+ A++H L T R +SY EL QV+ L + + GV G RVLI +P+ P +A
Sbjct: 87 KGEKCAIIHRDYLGQTHR-LSYRELWQQVNTLCSMMQSWGVKPGDRVLIALPMTPLVAVA 145
Query: 497 MLATNRIGAIHSVVFGGFAARELXTRI 577
MLA RIGA+H V++ L RI
Sbjct: 146 MLACARIGAVHVVLYSSITHEALMQRI 172
>UniRef50_A4WKF4 Cluster: AMP-dependent synthetase and ligase; n=3;
Pyrobaculum|Rep: AMP-dependent synthetase and ligase -
Pyrobaculum arsenaticum (strain DSM 13514 / JCM 11321)
Length = 633
Score = 98.3 bits (234), Expect = 1e-19
Identities = 56/152 (36%), Positives = 81/152 (53%)
Frame = +2
Query: 125 EYEKAQQRSLNDPEGFWGEVGSELEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDRH 304
+Y+K + SL PE FW S L W +PW ++++ + P +W+VGGE+S N V +H
Sbjct: 28 QYKKIYKESLK-PE-FWAREASYLIWERPWTKLVE-GDPPAVRWFVGGELSPYKNIVGKH 84
Query: 305 VVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPE 484
++ AL+ ++ +Y++L +R +G L LGV KG V+ Y P PE
Sbjct: 85 AGTWIWDKVALIWRGE-DGLIKTFTYSDLDQLAARYSGALRALGVGKGDWVMFYAPPTPE 143
Query: 485 AIIAMLATNRIGAIHSVVFGGFAARELXTRIE 580
I MLA RIGA VF GF +L RIE
Sbjct: 144 VIALMLAAVRIGAPFEPVFTGFGHGDLAMRIE 175
>UniRef50_Q8ZUB3 Cluster: Acetyl-coenzyme A synthetase; n=4;
Archaea|Rep: Acetyl-coenzyme A synthetase - Pyrobaculum
aerophilum
Length = 651
Score = 97.5 bits (232), Expect = 2e-19
Identities = 58/158 (36%), Positives = 88/158 (55%), Gaps = 6/158 (3%)
Frame = +2
Query: 125 EYEKAQQRSLNDPEGFWGE----VGSELEWTKPWDRVLD-DSNAPFTKWWVGGEMSVCYN 289
+YE R L D +G+W E + W K +++ + + PF KW+VGG + Y+
Sbjct: 7 KYE-VYNRWLQDSDGYWQEFIEKTAGYIYWAKKPEKIFEWNPPNPF-KWFVGGYTNAGYS 64
Query: 290 AVDRHVVNGR-GEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIY 466
AVD + GR G++ A ++ +P R+I+Y EL V R++ L GV KG +L+Y
Sbjct: 65 AVDYKL--GRFGDKTAYIYINPEASVERRITYGELYQLVCRISAALRAFGVKKGDTILVY 122
Query: 467 MPLVPEAIIAMLATNRIGAIHSVVFGGFAARELXTRIE 580
MP EA+ +LA RIGA+ S VF GF+ + + RIE
Sbjct: 123 MPNSIEAVAVLLAAARIGAVSSTVFAGFSPKAVADRIE 160
>UniRef50_Q72J94 Cluster: Acetyl-coenzyme A synthetase; n=2; Thermus
thermophilus|Rep: Acetyl-coenzyme A synthetase - Thermus
thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)
Length = 845
Score = 97.1 bits (231), Expect = 3e-19
Identities = 56/153 (36%), Positives = 80/153 (52%)
Frame = +2
Query: 122 PEYEKAQQRSLNDPEGFWGEVGSELEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDR 301
P+ A + SL DPE FW W +PW V + W+ GG +V NA+DR
Sbjct: 265 PDPRAAHRASLEDPEAFWEGFARGFAWERPWKAVFRREDRT---WFAGGLTNVALNALDR 321
Query: 302 HVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVP 481
H+ + +Q AL+ + K +Y E+++ SRLAG TLGV +G RV +Y+P
Sbjct: 322 HLPE-KAQQVALLTLDG-EGRLGKWTYKEVRELSSRLAGLFRTLGVGRGDRVALYLPTGL 379
Query: 482 EAIIAMLATNRIGAIHSVVFGGFAARELXTRIE 580
EA +A LA RIGA+H+ + G L R+E
Sbjct: 380 EAALAALACARIGAVHAALPLGLGPEALRRRLE 412
>UniRef50_Q1JYJ4 Cluster: AMP-dependent synthetase and ligase; n=1;
Desulfuromonas acetoxidans DSM 684|Rep: AMP-dependent
synthetase and ligase - Desulfuromonas acetoxidans DSM
684
Length = 621
Score = 96.7 bits (230), Expect = 4e-19
Identities = 47/130 (36%), Positives = 75/130 (57%)
Frame = +2
Query: 194 LEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDRHVVNGRGEQFALVHDSPLTDTVRK 373
+EW +P+ +VLD+ P+ +W+ GG+++V +N + RH+ R + AL+ + R
Sbjct: 38 IEWHEPYRKVLDNMAPPYYRWYTGGKLNVYHNILGRHLETERRNKAALIWRGANFEE-RT 96
Query: 374 ISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFA 553
+Y L +V + L LGV KG RVL++MP +PE +IAM+A IGAIH ++
Sbjct: 97 YTYQTLAHEVLAMINGLVHLGVKKGDRVLLFMPDIPETVIAMIACASIGAIHVAYHMAYS 156
Query: 554 ARELXTRIEH 583
A L R+ H
Sbjct: 157 AEALAQRLNH 166
>UniRef50_Q0FW37 Cluster: Acyl-CoA synthetase; n=1; Roseovarius sp.
HTCC2601|Rep: Acyl-CoA synthetase - Roseovarius sp.
HTCC2601
Length = 656
Score = 96.7 bits (230), Expect = 4e-19
Identities = 50/155 (32%), Positives = 81/155 (52%), Gaps = 3/155 (1%)
Frame = +2
Query: 131 EKAQQRSLNDPEGFWGEVGSEL--EWTKPWDRVLDDSNA-PFTKWWVGGEMSVCYNAVDR 301
E + S++DPE FW +L +T PW DDS F +W+ GG ++V + V R
Sbjct: 40 EDMHRASIDDPESFWPRALDDLGVTFTTPWSTFRDDSAGFAFPRWFSGGALNVATHCVTR 99
Query: 302 HVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVP 481
H + + V + R++S+ L +V R+A L LG+ KG RV +++P++P
Sbjct: 100 HAKDPEAAKRPAVISEADSGVCRELSFGALGAEVERVAAGLAALGIGKGDRVGLFLPVIP 159
Query: 482 EAIIAMLATNRIGAIHSVVFGGFAARELXTRIEHA 586
EA +A++A +IGA+ F G+ L R+ A
Sbjct: 160 EAAVALMACAKIGAVAVPAFSGYGPDPLAARLNAA 194
>UniRef50_A7DME3 Cluster: AMP-dependent synthetase and ligase; n=1;
Candidatus Nitrosopumilus maritimus SCM1|Rep:
AMP-dependent synthetase and ligase - Candidatus
Nitrosopumilus maritimus SCM1
Length = 641
Score = 96.7 bits (230), Expect = 4e-19
Identities = 51/150 (34%), Positives = 91/150 (60%), Gaps = 4/150 (2%)
Frame = +2
Query: 143 QRSLNDPEGFWGEVGSELE--WTKPWDRVLDDSNA-PFTKWWVGGEMSVCYNAVDRHV-V 310
++S ++ E FW EV ++ W P+ ++LD SN +KW+V G+ ++ + V++ V +
Sbjct: 35 KKSKDELEWFWQEVDKDIGVVWDSPYSQILDSSNGIAHSKWFVNGKTNIYKSTVEKFVKL 94
Query: 311 NGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAI 490
+ V + T K++Y EL ++VS+LA L +L V KG V IY+P++ EAI
Sbjct: 95 TPDKTAYHFVSEDGATS---KLTYQELDNKVSKLANGLKSLRVKKGDVVAIYLPMIQEAI 151
Query: 491 IAMLATNRIGAIHSVVFGGFAARELXTRIE 580
+A+LA+ +IGA+ +V+F G++ L R++
Sbjct: 152 LAILASAKIGAVQTVIFSGYSTESLHIRLQ 181
>UniRef50_Q39MW7 Cluster: AMP-dependent synthetase and ligase; n=1;
Burkholderia sp. 383|Rep: AMP-dependent synthetase and
ligase - Burkholderia sp. (strain 383) (Burkholderia
cepacia (strain ATCC 17760/ NCIB 9086 / R18194))
Length = 668
Score = 96.3 bits (229), Expect = 5e-19
Identities = 52/145 (35%), Positives = 84/145 (57%), Gaps = 3/145 (2%)
Frame = +2
Query: 161 PEGFWGEV--GSELEWTKPWDRVLDDSNA-PFTKWWVGGEMSVCYNAVDRHVVNGRGEQF 331
P+ +W + +L + +P+D V+D + + KW VGG + N +DR+ R Q
Sbjct: 52 PDDYWSALIRHMDLRFYQPYDAVVDTRDGIEWAKWCVGGTTNAVLNCLDRYRGTARDRQE 111
Query: 332 ALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATN 511
A+V + TVR+ +Y EL Q SRLA L +G +G + +Y+P+VPEA+ MLA +
Sbjct: 112 AVVWEGE-DGTVRRWTYAELDAQTSRLAAGLREIGCRQGDVIALYLPMVPEAVAGMLAIS 170
Query: 512 RIGAIHSVVFGGFAARELXTRIEHA 586
+IGAI +F GF A+ + +R++ A
Sbjct: 171 KIGAIVLPLFSGFGAQAVASRLQDA 195
>UniRef50_Q140P4 Cluster: Putative acetyl-CoA synthetase and ligase;
n=1; Burkholderia xenovorans LB400|Rep: Putative
acetyl-CoA synthetase and ligase - Burkholderia
xenovorans (strain LB400)
Length = 650
Score = 96.3 bits (229), Expect = 5e-19
Identities = 50/141 (35%), Positives = 81/141 (57%), Gaps = 1/141 (0%)
Frame = +2
Query: 161 PEGFWGEVGSELEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDRHVVNGR-GEQFAL 337
P+ +W V + W +PW+ V D N P K++ GG ++VC N VDR+ + + A+
Sbjct: 43 PDAYWEWVAKKFRWMRPWESVRD-GNFPEFKYFAGGMLNVCDNCVDRYAEDPHYASRPAI 101
Query: 338 VHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRI 517
+ D +SY +L+ +R A L +LGV +G V IY+P + E+ +A+ A NRI
Sbjct: 102 TWEGEPGDCAT-LSYAQLRTATARFANGLRSLGVGQGDVVAIYLPNMLESFVAIQACNRI 160
Query: 518 GAIHSVVFGGFAARELXTRIE 580
GAI++V+F GF+A R++
Sbjct: 161 GAIYTVLFAGFSADAAALRLQ 181
>UniRef50_A4A7V6 Cluster: Acetyl-coenzyme A synthetase/GroES-like
domain; n=4; Bacteria|Rep: Acetyl-coenzyme A
synthetase/GroES-like domain - Congregibacter litoralis
KT71
Length = 1809
Score = 96.3 bits (229), Expect = 5e-19
Identities = 52/141 (36%), Positives = 76/141 (53%), Gaps = 11/141 (7%)
Frame = +2
Query: 197 EWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDRHVVNGRGEQFALVHDSPLTDTVRK- 373
EW PW R DDS APF +W+ G + C+N VDRHV+ GRG+ A+V + D R
Sbjct: 75 EWF-PWTRAFDDSRAPFYRWYAGALTNACFNEVDRHVLAGRGDATAIVFEGDRWDPSRND 133
Query: 374 ----------ISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGA 523
+S+ +L + A L++LG+ +G R+ +P + E I A R+G
Sbjct: 134 GKGGPVQEITVSFRQLLAETVLRAEVLSSLGLKRGDRIAFNLPNILEQIFYTQAAKRLGI 193
Query: 524 IHSVVFGGFAARELXTRIEHA 586
I++ VFGGF+A+ L RI A
Sbjct: 194 IYTPVFGGFSAKTLSDRIYDA 214
>UniRef50_Q55GU6 Cluster: Putative acetyl-CoA synthetase; n=3;
Dictyostelium discoideum|Rep: Putative acetyl-CoA
synthetase - Dictyostelium discoideum AX4
Length = 684
Score = 95.9 bits (228), Expect = 6e-19
Identities = 52/154 (33%), Positives = 84/154 (54%), Gaps = 2/154 (1%)
Frame = +2
Query: 125 EYEKAQQRSLNDPEGFWGEVGSE-LEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDR 301
+YE S +P FW EV + + W K +D+V + W+ GGE++ CYN +D+
Sbjct: 9 DYENDYSYSQINPISFWDEVAKKFVHWDKIYDKVYSGDEI-YPDWFQGGELNTCYNVLDK 67
Query: 302 HVVNG-RGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLV 478
V N + ++ AL+++ K++Y +L ++V + L + +SK VLIYM
Sbjct: 68 QVKNPLKRDKDALIYECLYLKKTVKLTYYQLYEKVCEFSRVLLNINISKNDNVLIYMANT 127
Query: 479 PEAIIAMLATNRIGAIHSVVFGGFAARELXTRIE 580
E +IAML+ RIGA +V+F G+ + L RIE
Sbjct: 128 LEPLIAMLSCARIGATFTVLFEGYPVKSLIDRIE 161
>UniRef50_Q9HLJ9 Cluster: Acetyl-CoA synthetase related protein;
n=2; Thermoplasma|Rep: Acetyl-CoA synthetase related
protein - Thermoplasma acidophilum
Length = 619
Score = 95.5 bits (227), Expect = 8e-19
Identities = 57/148 (38%), Positives = 84/148 (56%), Gaps = 3/148 (2%)
Frame = +2
Query: 146 RSLNDPEGFWGEVGSEL--EWTKPWDRVLDDSNA-PFTKWWVGGEMSVCYNAVDRHVVNG 316
R+ DPE FW V +L E+ K +D V+D S P+ KW+ GG +++ YNAV+R+
Sbjct: 33 RADRDPEWFWPRVIDDLGLEFFKKFDHVMDLSEGVPWAKWFTGGRINIEYNAVERY---S 89
Query: 317 RGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIA 496
E A+V++S K+SY+EL +VS L+ + +G+ +G RV IYMP + IA
Sbjct: 90 DSENTAIVYESE-DGYKSKMSYSELNRKVSALSSAIHDMGIGRGDRVAIYMPFNANSAIA 148
Query: 497 MLATNRIGAIHSVVFGGFAARELXTRIE 580
A RIGAI +F G+ + RIE
Sbjct: 149 FYAVLRIGAIAVPMFSGYGVDAVRNRIE 176
>UniRef50_Q5P1M8 Cluster: Acyl-CoA synthetase; n=2; Azoarcus|Rep:
Acyl-CoA synthetase - Azoarcus sp. (strain EbN1)
(Aromatoleum aromaticum (strain EbN1))
Length = 663
Score = 94.7 bits (225), Expect = 1e-18
Identities = 50/154 (32%), Positives = 84/154 (54%), Gaps = 3/154 (1%)
Frame = +2
Query: 125 EYEKAQQRSLNDPEGFWGEV--GSELEWTKPWDRVLD-DSNAPFTKWWVGGEMSVCYNAV 295
+ + ++R+ +PE FW +V L+W P+ + LD + KW+VGG + + N V
Sbjct: 27 DLDDLRERAAREPERFWDQVLEAIGLDWATPYRQTLDLTDGVMWPKWFVGGRLDLVDNLV 86
Query: 296 DRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPL 475
+H + A+ + + +R +SY L +V R+A L LGVS+G R+ +Y+P+
Sbjct: 87 GKHA-RATPAKIAVRWEGDGGE-LRTLSYAALAGEVERVAAGLRALGVSEGERIALYLPM 144
Query: 476 VPEAIIAMLATNRIGAIHSVVFGGFAARELXTRI 577
V EA++ MLA RIGA+ F G+ A + R+
Sbjct: 145 VAEAVVTMLAATRIGAVFIPFFSGYGADSVAQRV 178
>UniRef50_Q4QBC0 Cluster: Acetyl-CoA synthetase, putative; n=6;
Eukaryota|Rep: Acetyl-CoA synthetase, putative -
Leishmania major
Length = 705
Score = 94.3 bits (224), Expect = 2e-18
Identities = 53/156 (33%), Positives = 87/156 (55%), Gaps = 10/156 (6%)
Frame = +2
Query: 149 SLNDPEGFWGEVGS-ELEWTKPW--DRVL-----DDSNAP-FTKWWVGGEMSVCYNAVDR 301
S+ + FW E+ + W W D+ + D S P F KW+ G ++CYNA+DR
Sbjct: 70 SIEHNDVFWAEIARRDFYWKTTWPDDQHVKSYNFDKSKGPIFVKWFEGAVTNICYNALDR 129
Query: 302 HVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLT-TLGVSKGARVLIYMPLV 478
H+ + ++ + K++Y + +V LA L G++KG RV +Y+P++
Sbjct: 130 HLPAHK-DRVCFYFEGNDPSVTEKVTYGSMYTRVVELANVLKHQYGITKGDRVGLYLPMI 188
Query: 479 PEAIIAMLATNRIGAIHSVVFGGFAARELXTRIEHA 586
P A +AMLA RIGA+ +V+FGGF+A+ L +R++ A
Sbjct: 189 PFAAVAMLACARIGAVITVIFGGFSAQALSSRLKDA 224
>UniRef50_Q9YCA8 Cluster: Acetyl-coenzyme A synthetase; n=2;
Archaea|Rep: Acetyl-coenzyme A synthetase - Aeropyrum
pernix
Length = 656
Score = 93.9 bits (223), Expect = 2e-18
Identities = 57/155 (36%), Positives = 86/155 (55%), Gaps = 4/155 (2%)
Frame = +2
Query: 128 YEKAQQRSLNDPEGFWGEVGSEL--EWTKPWDRVLDDSNA-PFTKWWVGGEMSVCYNAVD 298
YE+ +RS D + FWG + L EW + V+D S + +W+ GG ++ YN VD
Sbjct: 30 YEELVRRSSEDLKWFWGNLPEWLGVEWFREPKAVVDLSRGVEWAQWYRGGLLNAAYNVVD 89
Query: 299 RHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTT-LGVSKGARVLIYMPL 475
R V G G + A VR+ +Y +LKD+V R+A L+ G+ G V IY P+
Sbjct: 90 RIVKMGYGHREAFTWVGE-DGEVRRYTYLQLKDEVDRMAKLLSQDYGLGVGDVVAIYAPM 148
Query: 476 VPEAIIAMLATNRIGAIHSVVFGGFAARELXTRIE 580
+PE+I AMLA ++GA+ S +F GFA + R++
Sbjct: 149 MPESIAAMLAAMKVGAVASPIFSGFAPPAVAERLK 183
>UniRef50_Q9Y8M8 Cluster: Acetyl-coenzyme A synthetase; n=1;
Aeropyrum pernix|Rep: Acetyl-coenzyme A synthetase -
Aeropyrum pernix
Length = 140
Score = 93.9 bits (223), Expect = 2e-18
Identities = 48/115 (41%), Positives = 68/115 (59%), Gaps = 1/115 (0%)
Frame = +2
Query: 143 QRSLNDPEGFWGEVGSELEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDRHVVNGRG 322
++S+ D E FW E EL W KPW +VLD APF +W+VGGE ++ NA+DR +
Sbjct: 24 RKSIEDIERFWDERARELVWLKPWHQVLDRGKAPFYRWFVGGETNINLNALDRWIGTSVE 83
Query: 323 EQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTT-LGVSKGARVLIYMPLVPE 484
+ A + D R +SY +L +V+RLA L +GV G RV IY+P++PE
Sbjct: 84 NKVAYYWEGEPGDR-RVLSYGDLYREVNRLAYALKEYIGVKPGDRVAIYLPMIPE 137
>UniRef50_Q9RX55 Cluster: Acetyl-CoA synthase; n=4; cellular
organisms|Rep: Acetyl-CoA synthase - Deinococcus
radiodurans
Length = 642
Score = 93.1 bits (221), Expect = 4e-18
Identities = 71/180 (39%), Positives = 96/180 (53%), Gaps = 3/180 (1%)
Frame = +2
Query: 56 ALKKQPFVSAADIECYNVCGXTPEYEKAQQRSLND-PEG-FWGEVGSELEWTKPWDRVLD 229
AL P VS D TPE +AQQ L D P G +W V SEL W P L+
Sbjct: 4 ALLTTPLVSPTDA-LKKTAPVTPE--RAQQ--LRDMPAGDYWLSVASELTWDVPPTTALE 58
Query: 230 DSNAPFTKWWVGGEMSVCYNAVDRHVVNGRGEQFALVHDSPLTDTVRKI-SYNELKDQVS 406
+ F +++ G + +V N +DRH N + AL ++ D +++ SY +L D +
Sbjct: 59 GTFGDF-QYFPGAKGNVSVNCLDRHPKN----RVALYYERE--DGLKETWSYGDLTDATA 111
Query: 407 RLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFAARELXTRIEHA 586
R A L LGV KG RV IY+ VPEA IA+ A RIGAI+SV+F GF+A + R+ A
Sbjct: 112 RFAAALQDLGVDKGDRVAIYLSNVPEAFIAIHACYRIGAIYSVIFAGFSASAVRDRLTDA 171
>UniRef50_Q6L1R5 Cluster: Acetyl-coenzyme A synthetase; n=1;
Picrophilus torridus|Rep: Acetyl-coenzyme A synthetase -
Picrophilus torridus
Length = 396
Score = 90.2 bits (214), Expect = 3e-17
Identities = 49/151 (32%), Positives = 86/151 (56%)
Frame = +2
Query: 125 EYEKAQQRSLNDPEGFWGEVGSELEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDRH 304
+Y + ++S+ + +W V SEL W K WD + + P K+++ G +VC+N +DRH
Sbjct: 34 DYYQFYKKSIENIGDYWAGVASELYWFKKWD-INMHGDFPDFKFFLNGYSNVCFNCIDRH 92
Query: 305 VVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPE 484
+ + ++ A++ S + K+ Y L S+ A L ++G+ KG V I+MP E
Sbjct: 93 ALK-KPDKTAIIWLSEDGLEI-KMDYRSLMIYTSKFASYLRSIGIKKGDVVAIFMPNRIE 150
Query: 485 AIIAMLATNRIGAIHSVVFGGFAARELXTRI 577
+ IA+ A RIGAI++++F GF+ + L R+
Sbjct: 151 SFIAVHACYRIGAIYNIIFSGFSTKALLDRL 181
>UniRef50_A3VFU7 Cluster: Acetoacetyl-CoA synthase; n=1;
Rhodobacterales bacterium HTCC2654|Rep: Acetoacetyl-CoA
synthase - Rhodobacterales bacterium HTCC2654
Length = 667
Score = 89.0 bits (211), Expect = 7e-17
Identities = 51/151 (33%), Positives = 78/151 (51%), Gaps = 2/151 (1%)
Frame = +2
Query: 128 YEKAQQRSLNDPEGFWGEVGSELEWTKPWD--RVLDDSNAPFTKWWVGGEMSVCYNAVDR 301
Y + Q S+ DP GFW V + + +VL D P T+W+ G ++ N + R
Sbjct: 41 YRELQVWSVEDPAGFWRAVWDYFDVIHEGEIEQVLTDDPMPRTRWFTGTRLNYAENIL-R 99
Query: 302 HVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVP 481
H +G E+ ++H + + IS+ E+ QV +LA ++ +G+ G RV+ YMP +P
Sbjct: 100 HETSGDPERPMMMHCAETRPDIAAISWAEVAGQVRKLATRMREMGIEPGDRVVAYMPNIP 159
Query: 482 EAIIAMLATNRIGAIHSVVFGGFAARELXTR 574
E IAMLAT IG I S F A+ + R
Sbjct: 160 ETFIAMLATTAIGGIWSSAAPEFGAQTVIDR 190
>UniRef50_Q5V498 Cluster: Acyl-coenzyme A synthetases; n=5;
Halobacteriaceae|Rep: Acyl-coenzyme A synthetases -
Haloarcula marismortui (Halobacterium marismortui)
Length = 673
Score = 89.0 bits (211), Expect = 7e-17
Identities = 51/146 (34%), Positives = 79/146 (54%), Gaps = 5/146 (3%)
Frame = +2
Query: 164 EGFWGEVGS--ELEWTKPWDRVLDDSNAP-FTKWWVGGEMSVCYNAVDRHVVNGRGEQ-- 328
E FW + ++E+ +D+V D+S P FT W+ GG ++ +N +DRH +
Sbjct: 56 EWFWDLLPEYLDIEFFDAYDQVRDNSEGPQFTDWYAGGTINAAHNVLDRHAARDSPTRNT 115
Query: 329 FALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLAT 508
AL+ + D VR+I+Y+EL Q S++A L ++GV G V +YMP+VPE +
Sbjct: 116 VALIWEGEPGD-VREITYHELNRQASKVANYLESVGVGTGDTVGLYMPMVPEVASILYGC 174
Query: 509 NRIGAIHSVVFGGFAARELXTRIEHA 586
++GAI +F GF TRI A
Sbjct: 175 LKVGAIAVPIFSGFGVDATATRIADA 200
>UniRef50_Q4ST59 Cluster: Chromosome undetermined SCAF14300, whole
genome shotgun sequence; n=1; Tetraodon
nigroviridis|Rep: Chromosome undetermined SCAF14300,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 737
Score = 87.4 bits (207), Expect = 2e-16
Identities = 44/106 (41%), Positives = 64/106 (60%), Gaps = 1/106 (0%)
Frame = +2
Query: 263 GGEMSVCYNAVDRHVVNGR-GEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGV 439
G ++CYN +DR+V + G++ A + ++Y EL +V + A L + GV
Sbjct: 3 GASTNICYNVLDRNVHEKKLGDKVAFYWEGNEPGDELTVTYRELLQRVCQFANVLKSRGV 62
Query: 440 SKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFAARELXTRI 577
KG RV IYMP+V E ++AMLA RIGA+HS+VF GF++ L RI
Sbjct: 63 KKGDRVSIYMPMVVELVVAMLACARIGAVHSIVFAGFSSESLCERI 108
>UniRef50_Q3E187 Cluster: AMP-dependent synthetase and
ligase:Enoyl-CoA hydratase/isomerase; n=2; Chloroflexus
aurantiacus|Rep: AMP-dependent synthetase and
ligase:Enoyl-CoA hydratase/isomerase - Chloroflexus
aurantiacus J-10-fl
Length = 1822
Score = 85.8 bits (203), Expect = 7e-16
Identities = 47/138 (34%), Positives = 71/138 (51%), Gaps = 11/138 (7%)
Frame = +2
Query: 206 KPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDRHVVNGRGEQFALVHDSPLTD-------- 361
+PW + DDS APF +W+ GG + C+N VDRHV+ G G++ A + D
Sbjct: 87 QPWQQAFDDSEAPFYRWFSGGLTNACFNEVDRHVMMGYGDEVAYYFEGDRWDNSLNNGRG 146
Query: 362 ---TVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHS 532
I+ L +V + A L LG+ KG R+ + MP + I A R+G +++
Sbjct: 147 GPVVQETITRRRLLVEVVKAAQVLRDLGLKKGDRIALNMPNIMPQIYYTEAAKRLGILYT 206
Query: 533 VVFGGFAARELXTRIEHA 586
VFGGF+ + L RI +A
Sbjct: 207 PVFGGFSDKTLSDRIHNA 224
>UniRef50_Q0RXR5 Cluster: Acetate--CoA ligase; n=1; Rhodococcus sp.
RHA1|Rep: Acetate--CoA ligase - Rhodococcus sp. (strain
RHA1)
Length = 654
Score = 84.6 bits (200), Expect = 2e-15
Identities = 53/147 (36%), Positives = 79/147 (53%), Gaps = 4/147 (2%)
Frame = +2
Query: 158 DPEGFWGEVGS--ELEWTKPWDRVLDDSNAPF-TKWWVGGEMSVCYNAVDRHVVNGRGEQ 328
DP FW V +LEW + V D +AP TKW+ GG +++ NAVDR + GRG
Sbjct: 48 DPGWFWSYVADWLQLEWQREPTSVFDQLDAPHNTKWFPGGALNITDNAVDRWIRAGRGND 107
Query: 329 FALVHDSPLTD-TVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLA 505
AL + L D + + ++++L ++ R+A L G+ G V I +P+V EA +A LA
Sbjct: 108 TALSWE--LEDGSSGRWTFSQLSLEIDRVARGLIDAGIGFGDTVGIQLPMVREAAVAQLA 165
Query: 506 TNRIGAIHSVVFGGFAARELXTRIEHA 586
+IGAI +F GF + R+ A
Sbjct: 166 CAKIGAISVPIFSGFGTAAVIDRLRIA 192
>UniRef50_Q97WK0 Cluster: Acetyl-CoA synthetase; n=4;
Sulfolobaceae|Rep: Acetyl-CoA synthetase - Sulfolobus
solfataricus
Length = 571
Score = 83.8 bits (198), Expect = 3e-15
Identities = 46/154 (29%), Positives = 80/154 (51%), Gaps = 1/154 (0%)
Frame = +2
Query: 125 EYEKAQQRSLNDPEGFWGEVGSELEWTKPWDRVLD-DSNAPFTKWWVGGEMSVCYNAVDR 301
+Y SL PE +W + L + K W++V++ + P KW++ G ++ YNA++
Sbjct: 2 DYYTLYDLSLEKPETYWETFANRLSFFKKWEKVIEKNKQLPIAKWFINGTTNIAYNALNH 61
Query: 302 HVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVP 481
G+ AL+ +I+++EL + S +AG L GV +G R+ IYMP
Sbjct: 62 ---GGK----ALIFYQENKHKGDEITFDELNNMSSMIAGLLLDKGVRRGDRIAIYMPNSI 114
Query: 482 EAIIAMLATNRIGAIHSVVFGGFAARELXTRIEH 583
I +LA R+GAI++++F G + +RI +
Sbjct: 115 CTIATILAAARLGAIYTLIFAGLGINAIVSRISN 148
>UniRef50_A7JC22 Cluster: Predicted protein; n=1; Francisella
tularensis subsp. tularensis FSC033|Rep: Predicted
protein - Francisella tularensis subsp. tularensis
FSC033
Length = 147
Score = 83.4 bits (197), Expect = 4e-15
Identities = 42/108 (38%), Positives = 60/108 (55%), Gaps = 1/108 (0%)
Frame = +2
Query: 128 YEKAQQRSLNDPEGFWGEVGSELEWTKPWDRVLDDSNAPF-TKWWVGGEMSVCYNAVDRH 304
YEK + SL +PE FW + + + W KP+ + + S AP KW+ GE++VCYN VDRH
Sbjct: 23 YEKLYKESLENPEQFWTKQANRIHWHKPFTKAYNSSFAPVDIKWFDDGELNVCYNCVDRH 82
Query: 305 VVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKG 448
+ R Q A + + +KI+Y EL +V +A L GV KG
Sbjct: 83 -LPARANQVAFIWQADNPKKSKKITYRELYHRVCEMANILEANGVKKG 129
>UniRef50_A5UY60 Cluster: AMP-dependent synthetase and ligase; n=2;
Roseiflexus|Rep: AMP-dependent synthetase and ligase -
Roseiflexus sp. RS-1
Length = 1912
Score = 82.6 bits (195), Expect = 6e-15
Identities = 44/138 (31%), Positives = 72/138 (52%), Gaps = 11/138 (7%)
Frame = +2
Query: 206 KPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDRHVVNGRGEQFALVHDSPLTDTVRK---- 373
+PW+R + + PF +W+ GG + C+N VDRHV+ G G++ A + D+
Sbjct: 85 EPWERAFNGDDPPFYRWFEGGLTNACFNEVDRHVLTGYGDEVAFYFEGDRWDSSLNNGRG 144
Query: 374 -------ISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHS 532
++ +L +V + A L LG+ G R+ + MP + E I A R+G I++
Sbjct: 145 GPVVSFAVTRKQLMLEVVKAAQVLRDLGLKTGDRIALNMPNIMEQIYYTEAAKRLGIIYT 204
Query: 533 VVFGGFAARELXTRIEHA 586
VFGGF+ + L RI +A
Sbjct: 205 PVFGGFSDKTLSDRIHNA 222
>UniRef50_A3WE14 Cluster: Acetyl-coenzyme A synthetase; n=1;
Erythrobacter sp. NAP1|Rep: Acetyl-coenzyme A synthetase
- Erythrobacter sp. NAP1
Length = 1850
Score = 81.0 bits (191), Expect = 2e-14
Identities = 43/138 (31%), Positives = 73/138 (52%), Gaps = 11/138 (7%)
Frame = +2
Query: 206 KPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDRHVVNGRGEQFALVHDSPLTDTVRK---- 373
+PW+R +D + P +W+ GG S +N VDRHV++G G++ A++ + + +
Sbjct: 95 EPWERAFNDDDPPNWRWFEGGLTSTAFNEVDRHVLSGHGDEAAMIFEGDRWNMASEGGRG 154
Query: 374 -------ISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHS 532
IS +L + ++ A L LG+ G R+ + MP +PE I R+G +++
Sbjct: 155 GPVDSEVISRRKLLLESAKCALALKALGLEAGDRIALNMPSIPEQIYWTEGAKRMGIVYT 214
Query: 533 VVFGGFAARELXTRIEHA 586
VFGGF+ + L RI A
Sbjct: 215 PVFGGFSDKTLSDRIADA 232
>UniRef50_Q01NM8 Cluster: AMP-dependent synthetase and ligase; n=1;
Solibacter usitatus Ellin6076|Rep: AMP-dependent
synthetase and ligase - Solibacter usitatus (strain
Ellin6076)
Length = 610
Score = 78.6 bits (185), Expect = 1e-13
Identities = 42/146 (28%), Positives = 77/146 (52%), Gaps = 3/146 (2%)
Frame = +2
Query: 149 SLNDPEGFWGEVGSEL--EWTKPWDRVLDDSNAP-FTKWWVGGEMSVCYNAVDRHVVNGR 319
S +PE FWGE+ E+ EW P+ + LD S P + +W++GG +++ +N +DR +
Sbjct: 38 SRENPERFWGEMMREMRVEWFTPYSKELDLSGGPEWARWFIGGRLNIAHNCLDRWADS-- 95
Query: 320 GEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAM 499
+ A + + + +++ EL++Q +R A L LG+ G RV + +P+ PE + +
Sbjct: 96 -DCAACIWEGE-SGAGGTLTFRELREQANRTANGLRALGLEAGDRVALCLPMTPEILPIL 153
Query: 500 LATNRIGAIHSVVFGGFAARELXTRI 577
+ G +F GF + TR+
Sbjct: 154 YGCFKAGLTVVPIFAGFGTGAIATRL 179
>UniRef50_Q54YU2 Cluster: Putative uncharacterized protein; n=1;
Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein - Dictyostelium discoideum AX4
Length = 261
Score = 78.2 bits (184), Expect = 1e-13
Identities = 41/120 (34%), Positives = 69/120 (57%)
Frame = +2
Query: 206 KPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDRHVVNGRGEQFALVHDSPLTDTVRKISYN 385
K ++ + + +N +W+ G ++ CYNA+D+H+VNGRGE+ A VH+ P +I+Y
Sbjct: 27 KEYENIYNSNN---NEWFSSGLLNACYNALDKHIVNGRGEEIAFVHEIPSKQISTQITYK 83
Query: 386 ELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFAAREL 565
+L D+V + V+IYM + II+ L+ RIGA H+++FGG+ + L
Sbjct: 84 QLFDKVCDI--------------VIIYMQNSIKLIISTLSCCRIGATHNIIFGGYTQKGL 129
>UniRef50_O30042 Cluster: Acetyl-CoA synthetase; n=1; Archaeoglobus
fulgidus|Rep: Acetyl-CoA synthetase - Archaeoglobus
fulgidus
Length = 662
Score = 77.0 bits (181), Expect = 3e-13
Identities = 51/153 (33%), Positives = 78/153 (50%), Gaps = 2/153 (1%)
Frame = +2
Query: 128 YEKAQQRSLNDPEGFWGEVGS--ELEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDR 301
Y+ + S+ + E FW V E++ + VLD+ P KW+ G ++ +A
Sbjct: 47 YKNLWKWSVENLEDFWESVWEFFEIKSYSDYKTVLDERKMPGAKWFEGATLNYAEHAF-- 104
Query: 302 HVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVP 481
+ G GE V + L R ++++EL+ Q + A L +GV KG RV+ Y VP
Sbjct: 105 -LKAGEGEAVVYVREDGLR---RALTWSELERQTAAFAAWLKDMGVKKGDRVVAYCSQVP 160
Query: 482 EAIIAMLATNRIGAIHSVVFGGFAARELXTRIE 580
EA+IA+LAT IGAI + V G A R + R +
Sbjct: 161 EAVIALLATASIGAIWAAVGGEVAPRAVIDRFK 193
>UniRef50_Q397N8 Cluster: Acetoacetyl-CoA synthase; n=5;
Bacteria|Rep: Acetoacetyl-CoA synthase - Burkholderia
sp. (strain 383) (Burkholderia cepacia (strain ATCC
17760/ NCIB 9086 / R18194))
Length = 665
Score = 76.2 bits (179), Expect = 5e-13
Identities = 47/154 (30%), Positives = 75/154 (48%), Gaps = 2/154 (1%)
Frame = +2
Query: 125 EYEKAQQRSLNDPEGFWGEVGS--ELEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVD 298
+Y+ + S+ +P+ FW + +++ RV D + P T+W+ ++ + +
Sbjct: 38 DYDALWRWSVREPDAFWASIWQWYGVQYDGSARRVTDGAPMPHTRWFPDARVNYAEHVLQ 97
Query: 299 RHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLV 478
G F H + T ++ +S EL QV R+A +L LGV G RV+ Y+P V
Sbjct: 98 NAAHAGAAPAF---HYASETRPLQTMSLAELASQVRRVATRLRDLGVVPGDRVVAYLPNV 154
Query: 479 PEAIIAMLATNRIGAIHSVVFGGFAARELXTRIE 580
PE +AMLAT IGAI S F R + R +
Sbjct: 155 PECAVAMLATTAIGAIWSSAAIDFGVRTVVDRFQ 188
>UniRef50_A3W6I7 Cluster: AMP-dependent synthetase and ligase; n=2;
Rhodobacteraceae|Rep: AMP-dependent synthetase and
ligase - Roseovarius sp. 217
Length = 645
Score = 75.8 bits (178), Expect = 7e-13
Identities = 46/157 (29%), Positives = 83/157 (52%), Gaps = 4/157 (2%)
Frame = +2
Query: 128 YEKAQQRSLNDPEGFWGEV--GSELEWTKPWDRVLDDSNAPFT-KWWVGGEMSVCYNAVD 298
YE +R+ P+ FW + + + +++P+ ++ D P + +W VG +++ +D
Sbjct: 26 YEDLVRRANAAPDWFWRRIIDHAGIRFSRPYLQLRDIFKGPESIRWAVGAALNLTETCLD 85
Query: 299 RHVVNGRGEQFALVHDSPLTDTVRKI-SYNELKDQVSRLAGKLTTLGVSKGARVLIYMPL 475
+ G ++ +V D D R+ +Y EL + +R+A L GV G RV IYMP+
Sbjct: 86 ARIEEGLADK--MVIDWVGEDASRRCWTYAELAAETARVASALAARGVKPGERVGIYMPM 143
Query: 476 VPEAIIAMLATNRIGAIHSVVFGGFAARELXTRIEHA 586
+PE A+L R+GA+ +F GFA + +R++ A
Sbjct: 144 IPEIAAALLGIARLGAVAVPLFSGFAPPAIVSRLQDA 180
>UniRef50_A4T5I6 Cluster: Acetoacetyl-CoA synthase; n=2;
Mycobacterium|Rep: Acetoacetyl-CoA synthase -
Mycobacterium gilvum PYR-GCK
Length = 637
Score = 74.1 bits (174), Expect = 2e-12
Identities = 46/152 (30%), Positives = 75/152 (49%)
Frame = +2
Query: 122 PEYEKAQQRSLNDPEGFWGEVGSELEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDR 301
P+Y S+ D E FW + + + VL + P +W+ G E++ + V R
Sbjct: 38 PDYHALWAWSVEDVEEFWAALWDYFDLGERAQPVLQSAEMPGAQWFPGTEINYV-DQVMR 96
Query: 302 HVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVP 481
HV R + D+P R++S+ EL + + A +L GV G RV+ Y+P +P
Sbjct: 97 HVRTDRPAILHVSEDAP----DREVSWAELLGRTAAFADRLRAAGVESGDRVVGYLPNIP 152
Query: 482 EAIIAMLATNRIGAIHSVVFGGFAARELXTRI 577
EA++A LAT IGA+ S ++A+ R+
Sbjct: 153 EAVVAFLATASIGAVWSACGQDYSAKAALDRL 184
>UniRef50_Q9KZN9 Cluster: Acetoacetyl-CoA synthetase; n=5;
Actinobacteria (class)|Rep: Acetoacetyl-CoA synthetase -
Streptomyces coelicolor
Length = 658
Score = 72.5 bits (170), Expect = 7e-12
Identities = 44/153 (28%), Positives = 80/153 (52%), Gaps = 2/153 (1%)
Frame = +2
Query: 128 YEKAQQRSLNDPEGFWGEVGS--ELEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDR 301
Y + S+++ + FW V ++ ++ P RVL D P +W+ G ++ +A+
Sbjct: 41 YAALHRWSVDELDTFWKAVTEWFDVRFSTPCARVLGDRTMPGAQWFPGATLNYAEHAL-- 98
Query: 302 HVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVP 481
R ++ AL++ T +++ EL+ QV+ LA +L LGV G RV Y+P +P
Sbjct: 99 RAAGTRPDEPALLYVDE-THEPAPVTWAELRRQVASLAAELRALGVRPGDRVSGYLPNIP 157
Query: 482 EAIIAMLATNRIGAIHSVVFGGFAARELXTRIE 580
+A++A+LAT +G + + F AR + R +
Sbjct: 158 QAVVALLATAAVGGVWTSCAPDFGARSVLDRFQ 190
>UniRef50_A5WDS3 Cluster: AMP-dependent synthetase and ligase; n=5;
Gammaproteobacteria|Rep: AMP-dependent synthetase and
ligase - Psychrobacter sp. PRwf-1
Length = 554
Score = 72.5 bits (170), Expect = 7e-12
Identities = 36/96 (37%), Positives = 56/96 (58%)
Frame = +2
Query: 299 RHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLV 478
RHV NG G++ ALVH+ + ++S+NEL + +++A L GV G RV +P
Sbjct: 48 RHVRNGLGDKVALVHEDT-KQKITQLSFNELDQRSAQVANLLKAYGVKAGDRVATMLPRT 106
Query: 479 PEAIIAMLATNRIGAIHSVVFGGFAARELXTRIEHA 586
PE +I +LAT R+GAI+ +F F + R++ A
Sbjct: 107 PELLIVVLATWRVGAIYQPLFTAFGVESIAYRLDKA 142
>UniRef50_Q12HA7 Cluster: Acetoacetyl-CoA synthase precursor; n=6;
Proteobacteria|Rep: Acetoacetyl-CoA synthase precursor -
Polaromonas sp. (strain JS666 / ATCC BAA-500)
Length = 696
Score = 69.3 bits (162), Expect = 6e-11
Identities = 47/142 (33%), Positives = 71/142 (50%), Gaps = 6/142 (4%)
Frame = +2
Query: 128 YEKAQQRSLNDPEGFWGEVGS--ELEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDR 301
Y+ + S+ D E FW + EL+ P VL D P +W+ G +++ + R
Sbjct: 27 YDALWRWSVTDLEAFWQSIWDYFELQSPTPHTAVLADRRMPGARWFPGAQVNYARQVL-R 85
Query: 302 HVVNGRGEQF-ALVHD---SPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYM 469
HV F ALV+ S + R++S+ L+ QV+ LA L GV G RV Y+
Sbjct: 86 HVDKAHAAGFPALVNHNEKSLASGQHRELSWPALRQQVASLALHLKAQGVEPGDRVAAYL 145
Query: 470 PLVPEAIIAMLATNRIGAIHSV 535
P +PEA++A LA IG + S+
Sbjct: 146 PNIPEAMVAFLAVVSIGGVWSI 167
>UniRef50_Q86JR9 Cluster: Putative uncharacterized protein; n=2;
Dictyostelium discoideum|Rep: Putative uncharacterized
protein - Dictyostelium discoideum (Slime mold)
Length = 400
Score = 67.7 bits (158), Expect = 2e-10
Identities = 44/141 (31%), Positives = 69/141 (48%), Gaps = 1/141 (0%)
Frame = +2
Query: 161 PEGFWGEVGSE-LEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDRHVVNGRGEQFAL 337
PE FW EV + + W K +D+V + W+ +G+Q AL
Sbjct: 21 PEAFWDEVAKKNVFWDKMYDKVYSGDEM-YPDWF-------------------KGDQDAL 60
Query: 338 VHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRI 517
+++ P K++Y++L ++V + L L +SK VLIYM EA IA+L+
Sbjct: 61 IYECPYLKKTVKLTYHQLYEKVCEFSRVLLNLNISKNDNVLIYMANTVEAPIAILSCTHN 120
Query: 518 GAIHSVVFGGFAARELXTRIE 580
GA H V+F G++ + L RIE
Sbjct: 121 GATHCVLFDGYSVKSLIDRIE 141
>UniRef50_P39062 Cluster: Acetyl-coenzyme A synthetase; n=41;
cellular organisms|Rep: Acetyl-coenzyme A synthetase -
Bacillus subtilis
Length = 572
Score = 65.3 bits (152), Expect = 1e-09
Identities = 37/112 (33%), Positives = 57/112 (50%), Gaps = 1/112 (0%)
Frame = +2
Query: 254 WWVGGEMSVCYNAVDRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTL 433
W G+++ Y A+DRH + R + AL + D K ++ E+K++ +R L
Sbjct: 36 WHETGKLNAAYEAIDRHAESFRKNKVALYYKDAKRD--EKYTFKEMKEESNRAGNVLRRY 93
Query: 434 G-VSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFAARELXTRIEHA 586
G V KG RV I+MP PE ML +IGAI +F F + R+E++
Sbjct: 94 GNVEKGDRVFIFMPRSPELYFIMLGAIKIGAIAGPLFEAFMEGAVKDRLENS 145
>UniRef50_Q5KZW6 Cluster: Acetoacetyl-CoA synthetase; n=20;
Bacteria|Rep: Acetoacetyl-CoA synthetase - Geobacillus
kaustophilus
Length = 667
Score = 64.5 bits (150), Expect = 2e-09
Identities = 44/151 (29%), Positives = 75/151 (49%), Gaps = 2/151 (1%)
Frame = +2
Query: 128 YEKAQQRSLNDPEGFWGEVGSE--LEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDR 301
Y + S+ E FW V ++ P++ VL + P +W+ G ++ + + R
Sbjct: 46 YRELWTWSVEHLEEFWETVWEYCGVQAATPYECVLRERKMPGAEWFPGAALNYAKH-IFR 104
Query: 302 HVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVP 481
H R ++ A++ S R++S+ EL ++ + +A L +GV +G RV+ YMP +P
Sbjct: 105 HA---RADRPAIIFRSERVP-YREVSWQELGEKTAAIAKALRAMGVKRGDRVVAYMPNIP 160
Query: 482 EAIIAMLATNRIGAIHSVVFGGFAARELXTR 574
E ++A LA IGAI S F A + R
Sbjct: 161 ETVMAFLACASIGAIWSSCSPDFGAGSVIDR 191
>UniRef50_A1IEB0 Cluster: Acetoacetyl-CoA synthase; n=1; Candidatus
Desulfococcus oleovorans Hxd3|Rep: Acetoacetyl-CoA
synthase - Candidatus Desulfococcus oleovorans Hxd3
Length = 295
Score = 64.5 bits (150), Expect = 2e-09
Identities = 43/153 (28%), Positives = 76/153 (49%), Gaps = 3/153 (1%)
Frame = +2
Query: 125 EYEKAQQRSLNDPEGFWGEVG--SELEWTKPWDRVLDD-SNAPFTKWWVGGEMSVCYNAV 295
EY++ S+ + FW +++ + P+D V+DD P +W+ G ++ N
Sbjct: 51 EYDELYHWSVRNISDFWAAFWDFAQIRCSSPFDCVVDDVGKMPGARWFEGARLNFAEN-- 108
Query: 296 DRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPL 475
++ R + AL+ + ++R ++Y +L D+V+ L L LG+ G RV +MP
Sbjct: 109 ---LLRYRDDHSALIFKAEGRPSIR-MTYRQLYDEVAGLVISLKALGLKPGDRVAGFMPN 164
Query: 476 VPEAIIAMLATNRIGAIHSVVFGGFAARELXTR 574
+P+ IIAMLA +GA S F + + R
Sbjct: 165 MPQTIIAMLAATSLGATWSSCSPDFGIKGVMDR 197
>UniRef50_Q8ZV30 Cluster: Acetyl-coenzyme A synthetase; n=6;
Thermoprotei|Rep: Acetyl-coenzyme A synthetase -
Pyrobaculum aerophilum
Length = 626
Score = 64.1 bits (149), Expect = 2e-09
Identities = 46/150 (30%), Positives = 71/150 (47%), Gaps = 6/150 (4%)
Frame = +2
Query: 149 SLNDPEGFWGEVGSE---LEWTKPWDRVLDDSNA-PFTKWWVGGEMSVCYNAVD--RHVV 310
+ + PE FW E L W + + +VLD S + +W+VGG++++ D R +V
Sbjct: 35 TFDKPEEFWRSFEKEVLKLGWYEEYIKVLDLSKGVQWPRWFVGGKINIADQLEDSSRPLV 94
Query: 311 NGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAI 490
GE + SY+E+ + +A L G+ KG RV I+MP+VPE I
Sbjct: 95 KWEGED----------GSTAVWSYSEVLYKAKAVASWLKRNGLEKGDRVAIFMPMVPEII 144
Query: 491 IAMLATNRIGAIHSVVFGGFAARELXTRIE 580
ML R G + +F GF + R+E
Sbjct: 145 PVMLGAIRAGGVIVPLFSGFGKEAIRVRLE 174
>UniRef50_UPI00005102FE Cluster: COG0365: Acyl-coenzyme A
synthetases/AMP-(fatty) acid ligases; n=1;
Brevibacterium linens BL2|Rep: COG0365: Acyl-coenzyme A
synthetases/AMP-(fatty) acid ligases - Brevibacterium
linens BL2
Length = 680
Score = 63.7 bits (148), Expect = 3e-09
Identities = 43/146 (29%), Positives = 74/146 (50%), Gaps = 4/146 (2%)
Frame = +2
Query: 149 SLNDPEGFWGEVGS--ELEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDRHVVNGRG 322
S+ D E FW V +++ P+ VL++ P +W+ G ++ +++ G
Sbjct: 43 SITDIEDFWESVWEYFDVKSHSPYTSVLEERVMPHARWFTGATLNYAEHSL------GAP 96
Query: 323 EQFALVHDSPLTDTVRK--ISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIA 496
EQ V + ++ T ++Y EL+ +V+R+ L LGV KG RV+ Y+P PEA++A
Sbjct: 97 EQADEVAVTAVSQTREDFTLTYAELRREVARVRAGLIDLGVKKGDRVVGYLPNQPEALVA 156
Query: 497 MLATNRIGAIHSVVFGGFAARELXTR 574
LA +GAI + F + + R
Sbjct: 157 FLAAASLGAIWASCAPEFGTQSVIDR 182
>UniRef50_A4QIB2 Cluster: Putative uncharacterized protein; n=1;
Corynebacterium glutamicum R|Rep: Putative
uncharacterized protein - Corynebacterium glutamicum
(strain R)
Length = 675
Score = 63.7 bits (148), Expect = 3e-09
Identities = 42/156 (26%), Positives = 73/156 (46%), Gaps = 3/156 (1%)
Frame = +2
Query: 122 PEYEKAQQRSLNDPEGFWGEVGSELEWT-KPWD--RVLDDSNAPFTKWWVGGEMSVCYNA 292
P++ S+ + E FW + S + + +D VL + PF W+ G ++ N
Sbjct: 44 PDFHSLLDWSVTEVEAFWRSIQSYFDVIGEGFDTSEVLKEHVMPFASWFPGARVNFAENV 103
Query: 293 VDRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMP 472
+ RH N ++ + +S+ +L+ QV+ LA LGV +G R+ +P
Sbjct: 104 L-RHAHNPLLANEPAIYQVEEDGSHTVLSWVQLESQVASLAATFKELGVERGDRIAAVLP 162
Query: 473 LVPEAIIAMLATNRIGAIHSVVFGGFAARELXTRIE 580
VPEAII +LA IGA+ ++ +A R++
Sbjct: 163 NVPEAIIGLLAAASIGAVWTINSPDLSAEASIRRVK 198
>UniRef50_Q8IWD2 Cluster: Acetoacetyl-CoA synthetase; n=53;
Eumetazoa|Rep: Acetoacetyl-CoA synthetase - Homo sapiens
(Human)
Length = 672
Score = 63.3 bits (147), Expect = 4e-09
Identities = 48/160 (30%), Positives = 75/160 (46%), Gaps = 5/160 (3%)
Frame = +2
Query: 110 CGXTPE-YEKAQQRSLNDPEGFWGEVG--SELEWTKPWDRVLDDSN--APFTKWWVGGEM 274
CG E Y+ S+ FW E S + +++ +D V+D S A +W+ G +
Sbjct: 40 CGLALESYDDLYHWSVESYSDFWAEFWKFSGIVFSRVYDEVVDTSKGIADVPEWFKGSRL 99
Query: 275 SVCYNAVDRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGAR 454
+ N + RH N R AL + + K+++ EL+ +V+ A + +GV KG R
Sbjct: 100 NYAENLL-RHKENDR---VALYVAREGKEEIVKVTFEELRQEVALFAAAMRKMGVKKGDR 155
Query: 455 VLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFAARELXTR 574
V+ Y+P A+ AMLA IGAI S F + R
Sbjct: 156 VVGYLPNSEHAVEAMLAAASIGAIWSSTSPDFGVNGVLDR 195
>UniRef50_Q0S3K9 Cluster: Acetoacetate--CoA ligase; n=10;
Actinomycetales|Rep: Acetoacetate--CoA ligase -
Rhodococcus sp. (strain RHA1)
Length = 647
Score = 62.9 bits (146), Expect = 5e-09
Identities = 48/154 (31%), Positives = 72/154 (46%), Gaps = 4/154 (2%)
Frame = +2
Query: 128 YEKAQQRSLNDPEGFWGEVGSELEW---TKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVD 298
Y + S+ DP FW +V E+ T P + DD+ P W+ G + N VD
Sbjct: 37 YRALWRWSIADPAAFWQDVWDYFEFRSATDPGPALADDA-MPGAVWFPGATL----NYVD 91
Query: 299 RHVVNGR-GEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPL 475
N R G L TD + ++EL+ V+ LA L GV G RV+ Y+P
Sbjct: 92 HVFRNARPGTPAILYAGEGATDV--SVGWDELRSAVAGLAVTLREHGVGVGDRVVGYLPN 149
Query: 476 VPEAIIAMLATNRIGAIHSVVFGGFAARELXTRI 577
+PEA++A LAT +GA+ + ++A R+
Sbjct: 150 IPEAVVAFLATASLGAVWAACGQDYSAPAALDRL 183
>UniRef50_A4TEH9 Cluster: Acetyl-CoA synthetase precursor; n=1;
Mycobacterium gilvum PYR-GCK|Rep: Acetyl-CoA synthetase
precursor - Mycobacterium gilvum PYR-GCK
Length = 280
Score = 62.5 bits (145), Expect = 7e-09
Identities = 39/108 (36%), Positives = 54/108 (50%), Gaps = 4/108 (3%)
Frame = +2
Query: 266 GEMSVCYNAVDRHVVNGRGEQFAL--VHDSPLTD--TVRKISYNELKDQVSRLAGKLTTL 433
G ++ Y AVDRH G + AL V +S LT +VR + Y+EL SR L L
Sbjct: 42 GLCNIAYAAVDRHAGGSAGGRTALRFVSESALTGETSVRDLEYSELASLSSRFTAVLRAL 101
Query: 434 GVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFAARELXTRI 577
GV KG RV + PE + +L R G++ S +F F + TR+
Sbjct: 102 GVGKGDRVFTLLGRCPELYVTILGALRNGSVVSPLFSAFGPEPVATRL 149
>UniRef50_Q11QU1 Cluster: Acetyl-CoA synthetase; n=1; Cytophaga
hutchinsonii ATCC 33406|Rep: Acetyl-CoA synthetase -
Cytophaga hutchinsonii (strain ATCC 33406 / NCIMB 9469)
Length = 653
Score = 61.7 bits (143), Expect = 1e-08
Identities = 42/145 (28%), Positives = 73/145 (50%), Gaps = 2/145 (1%)
Frame = +2
Query: 149 SLNDPEGFWGEVGSEL--EWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDRHVVNGRG 322
S++ EGFW + L ++ +P+ VL+ S+ P W+ + +N V+
Sbjct: 73 SIDKKEGFWKAMIDSLSIKFEQPYSSVLEKSDDPDQVHWL---KNARFNIVES-CFQAAS 128
Query: 323 EQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAML 502
EQ A+ + + + + ISY LK +V + A L+ G + R+++Y+P +AI L
Sbjct: 129 EQAAIFYQAEQSSEIHTISYGALKQKVIQYASGLSKNGFAAHDRIILYLPFSIDAIAFYL 188
Query: 503 ATNRIGAIHSVVFGGFAARELXTRI 577
A +GA +V F+A+EL RI
Sbjct: 189 ACIYMGAEPVLVSDSFSAQELTKRI 213
>UniRef50_A4TUE0 Cluster: Acyl-coenzyme A synthetases/AMP-(Fatty)
acid ligases; n=5; Proteobacteria|Rep: Acyl-coenzyme A
synthetases/AMP-(Fatty) acid ligases - Magnetospirillum
gryphiswaldense
Length = 588
Score = 61.3 bits (142), Expect = 2e-08
Identities = 41/133 (30%), Positives = 64/133 (48%)
Frame = +2
Query: 182 VGSELEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDRHVVNGRGEQFALVHDSPLTD 361
V EL+WT + NA M++ Y AVDRHV GRG++ A++ +
Sbjct: 20 VSPELDWTYARQNLSGPGNAG---------MNIAYAAVDRHVAAGRGDRPAILSLGRRYE 70
Query: 362 TVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVF 541
R++SY +L D +RLA L GV G +V + E +A ++GA++ +F
Sbjct: 71 K-RRLSYAQLADLSARLAAVLAAHGVGAGDKVAVLTGRSVELYVAAFGCWKVGAVYCPLF 129
Query: 542 GGFAARELXTRIE 580
F L +R+E
Sbjct: 130 SAFGPGPLKSRLE 142
>UniRef50_A1W234 Cluster: Acetoacetyl-CoA synthase; n=2;
Comamonadaceae|Rep: Acetoacetyl-CoA synthase -
Acidovorax sp. (strain JS42)
Length = 754
Score = 61.3 bits (142), Expect = 2e-08
Identities = 43/140 (30%), Positives = 71/140 (50%), Gaps = 3/140 (2%)
Frame = +2
Query: 125 EYEKAQQRSLNDPEGFWGEVGS--ELEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVD 298
+Y+ + S D + FW V +L+ P VL + P +W+ G +++ +
Sbjct: 35 DYDALWRWSTTDLDAFWQSVWDYFDLQSPTPHSAVLAKNVMPGAQWFPGAQVNYARQVL- 93
Query: 299 RHVVNGRGE-QFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPL 475
RHV + Q AL+ + + R++S+ L+ QV+ LA + GV G RV Y+P
Sbjct: 94 RHVDAAQAAGQPALIGRNERGER-RELSWPALRRQVAALALHMRAQGVQPGDRVAAYLPN 152
Query: 476 VPEAIIAMLATNRIGAIHSV 535
+PE I+A LA IGA+ S+
Sbjct: 153 IPETIVAFLACASIGAVWSL 172
>UniRef50_A0JS90 Cluster: AMP-dependent synthetase and ligase; n=16;
Bacteria|Rep: AMP-dependent synthetase and ligase -
Arthrobacter sp. (strain FB24)
Length = 607
Score = 61.3 bits (142), Expect = 2e-08
Identities = 35/104 (33%), Positives = 50/104 (48%)
Frame = +2
Query: 266 GEMSVCYNAVDRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSK 445
G +++ Y AVDRH R AL T R +SY EL +Q R AG L LG+ +
Sbjct: 52 GGVNIAYEAVDRHAAGERAGHEALRFIRS-DGTARSLSYAELAEQTGRFAGVLHRLGIGR 110
Query: 446 GARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFAARELXTRI 577
G RV M PE +A+L T + ++ +F F + R+
Sbjct: 111 GERVFSLMGRSPELYVAVLGTLKNASVFCPLFSAFGPEPVRQRL 154
>UniRef50_A1VP64 Cluster: Acetoacetyl-CoA synthase; n=2;
Comamonadaceae|Rep: Acetoacetyl-CoA synthase -
Polaromonas naphthalenivorans (strain CJ2)
Length = 667
Score = 60.9 bits (141), Expect = 2e-08
Identities = 41/140 (29%), Positives = 67/140 (47%), Gaps = 2/140 (1%)
Frame = +2
Query: 119 TPEYEKAQQRSLNDPEGFWGEVGSELEWTKPWDR--VLDDSNAPFTKWWVGGEMSVCYNA 292
T +Y++ + S+ D GFW + E +R + P +W+ ++ +
Sbjct: 42 TQDYDELWRWSIEDLPGFWQSIWDFFEVQADGEREPAMVGEQMPGIQWFPNARLNFAEH- 100
Query: 293 VDRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMP 472
V R+ + A +PL R+IS+ EL+ + LA +L + GV G RV +MP
Sbjct: 101 VFRNATSAHPVMLAHTEGAPL----REISWEELERTTAALAAQLRSWGVQPGDRVASFMP 156
Query: 473 LVPEAIIAMLATNRIGAIHS 532
+PE +IA LA +GAI S
Sbjct: 157 NLPETVIAFLACASVGAIWS 176
>UniRef50_Q0A597 Cluster: AMP-dependent synthetase and ligase; n=2;
Ectothiorhodospiraceae|Rep: AMP-dependent synthetase and
ligase - Alkalilimnicola ehrlichei (strain MLHE-1)
Length = 553
Score = 60.5 bits (140), Expect = 3e-08
Identities = 38/104 (36%), Positives = 53/104 (50%)
Frame = +2
Query: 266 GEMSVCYNAVDRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSK 445
G +++ Y A+DRHV G G+ ALV L + R SY EL + +R AG L GV
Sbjct: 23 GRLNMAYEALDRHVEAGGGDHEALVWRG-LDNERRASSYAELLEASARFAGALRARGVGL 81
Query: 446 GARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFAARELXTRI 577
G RV P PE IA L R GA+ + +F + + + R+
Sbjct: 82 GERVCTLAPRRPEPFIAGLGALRQGAVFAPLFPVYGPQPVRQRL 125
>UniRef50_A7IGG1 Cluster: AMP-dependent synthetase and ligase; n=1;
Xanthobacter autotrophicus Py2|Rep: AMP-dependent
synthetase and ligase - Xanthobacter sp. (strain Py2)
Length = 503
Score = 60.5 bits (140), Expect = 3e-08
Identities = 34/106 (32%), Positives = 58/106 (54%)
Frame = +2
Query: 263 GGEMSVCYNAVDRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVS 442
G + + + DRH+ R A++H+S ++ ++S+ L D SR A L T+G+
Sbjct: 73 GDAIPLAHLLCDRHLPGKRSHP-AMIHES-VSGQTSELSFGRLADYSSRFARVLATIGIR 130
Query: 443 KGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFAARELXTRIE 580
KG V + +P E IIA LA R+GA++ +F ++A + R+E
Sbjct: 131 KGDCVAVMLPKGVELIIAALAIWRVGAVYMPLFSTYSASAVNARLE 176
>UniRef50_Q7W0W3 Cluster: Acetyl-CoA synthetase; n=2;
Bordetella|Rep: Acetyl-CoA synthetase - Bordetella
parapertussis
Length = 543
Score = 60.1 bits (139), Expect = 4e-08
Identities = 40/111 (36%), Positives = 55/111 (49%)
Frame = +2
Query: 254 WWVGGEMSVCYNAVDRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTL 433
W + + + +DRH +GR ALV R SY EL +Q R A L L
Sbjct: 23 WGEAHAVDLAHAIIDRHRASGRT---ALVFIDQQGRESRH-SYAELAEQSDRAANLLARL 78
Query: 434 GVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFAARELXTRIEHA 586
GV G RV +P PE ++AMLA +IGAI+ +F GF + R+ H+
Sbjct: 79 GVRPGDRVAGLLPRGPEILVAMLAAIKIGAIYVPIFTGFKRDAIEYRLGHS 129
>UniRef50_Q8ESW2 Cluster: Acetoacetyl-CoA synthetase; n=1;
Oceanobacillus iheyensis|Rep: Acetoacetyl-CoA synthetase
- Oceanobacillus iheyensis
Length = 661
Score = 59.7 bits (138), Expect = 5e-08
Identities = 40/154 (25%), Positives = 75/154 (48%), Gaps = 2/154 (1%)
Frame = +2
Query: 125 EYEKAQQRSLNDPEGFWGEVGSELEWTK--PWDRVLDDSNAPFTKWWVGGEMSVCYNAVD 298
+Y + S++D FW + P+ V+ ++ P ++W+ +++ + V
Sbjct: 39 DYASLWKWSVDDISSFWETIWEYFNVISHHPYQHVISSTSMPGSRWFKEAKVNYAEH-VF 97
Query: 299 RHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLV 478
+H N A++H S T ++IS+ +L + L L +GV+KG RV+ Y P +
Sbjct: 98 KHKDNSNP---AIIHASE-TRGKQEISWQQLYQDTTALQLTLKNIGVTKGDRVVSYAPNI 153
Query: 479 PEAIIAMLATNRIGAIHSVVFGGFAARELXTRIE 580
E ++A LAT+ +GAI S F + + R +
Sbjct: 154 YETVVAFLATSSLGAIWSSASPDFGKQSVIERFQ 187
>UniRef50_Q8F6X6 Cluster: Acetyl-CoA synthetase; n=3; Bacteria|Rep:
Acetyl-CoA synthetase - Leptospira interrogans
Length = 660
Score = 58.8 bits (136), Expect = 9e-08
Identities = 49/153 (32%), Positives = 77/153 (50%), Gaps = 4/153 (2%)
Frame = +2
Query: 128 YEKAQQRSLNDPEGFWGEVG--SELEWTKPWDRVLDD-SNAPFTKWWVGGEMSVCYNAVD 298
+E+ + S+N+ FW + SE+ ++ +D V SN +K++ G +++ N +
Sbjct: 36 FEELRVWSVNEIGSFWESIWEFSEVVHSQKYDLVYQSGSNFTDSKFFPGAKLNFAENLLR 95
Query: 299 RHVVNGRGEQF-ALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPL 475
R + F AL++ + R++SY EL V +A L GV G RV+ MP
Sbjct: 96 RT------DSFPALIYRGE-DGSKREVSYAELYSYVGAVATDLKKRGVVPGDRVVGLMPN 148
Query: 476 VPEAIIAMLATNRIGAIHSVVFGGFAARELXTR 574
VPE +IAMLAT IGAI S F + + R
Sbjct: 149 VPETVIAMLATTSIGAIWSSCSPDFGVKGVLDR 181
>UniRef50_O28347 Cluster: Long-chain-fatty-acid--CoA ligase; n=1;
Archaeoglobus fulgidus|Rep: Long-chain-fatty-acid--CoA
ligase - Archaeoglobus fulgidus
Length = 509
Score = 58.4 bits (135), Expect = 1e-07
Identities = 30/73 (41%), Positives = 42/73 (57%)
Frame = +2
Query: 368 RKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGG 547
++ISY ELK+ +RLA L LGV KG RV +P+ PE + LA ++IGAI +
Sbjct: 30 KEISYGELKENANRLAASLLKLGVGKGDRVATVLPMTPEYVCTFLACSKIGAICVPMDVR 89
Query: 548 FAARELXTRIEHA 586
+ EL + HA
Sbjct: 90 YRTAELRRFLSHA 102
>UniRef50_A6C4K4 Cluster: Acetate--CoA ligase; n=1; Planctomyces
maris DSM 8797|Rep: Acetate--CoA ligase - Planctomyces
maris DSM 8797
Length = 679
Score = 56.8 bits (131), Expect = 4e-07
Identities = 26/88 (29%), Positives = 48/88 (54%)
Frame = +2
Query: 317 RGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIA 496
+ EQ A++ TD V+++SY EL+ +R+A LT G+ G R+ + +P+ PE++
Sbjct: 160 KSEQIAILFQRS-TDEVQQLSYRELRALTARVANGLTEAGIEPGERIAVMLPMTPESVAI 218
Query: 497 MLATNRIGAIHSVVFGGFAARELXTRIE 580
L G + + F+A E+ R++
Sbjct: 219 FLGIIAAGCVVVTIADSFSAEEMQVRLK 246
>UniRef50_Q5UWB7 Cluster: Acyl-coenzyme A synthetases; n=2;
Halobacteriaceae|Rep: Acyl-coenzyme A synthetases -
Haloarcula marismortui (Halobacterium marismortui)
Length = 616
Score = 56.8 bits (131), Expect = 4e-07
Identities = 37/123 (30%), Positives = 64/123 (52%)
Frame = +2
Query: 212 WDRVLDDSNAPFTKWWVGGEMSVCYNAVDRHVVNGRGEQFALVHDSPLTDTVRKISYNEL 391
WD + D++ W ++++ + DRH + RG Q AL + + K+++ EL
Sbjct: 75 WDDIYADAD-----WDAPNDLNIGHEVADRHATD-RG-QVAL-YQVGTDGELSKMTFWEL 126
Query: 392 KDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFAARELXT 571
D+ S+ A L LGV++G RV YMP +PE +A++ T + GA+ V F +
Sbjct: 127 ADRSSQFANVLDDLGVAQGDRVFSYMPRIPEHYVALVGTLKHGAVWGSVNERFGPDGISY 186
Query: 572 RIE 580
R++
Sbjct: 187 RLD 189
>UniRef50_Q39MD9 Cluster: AMP-dependent synthetase and ligase; n=2;
Burkholderia|Rep: AMP-dependent synthetase and ligase -
Burkholderia sp. (strain 383) (Burkholderia cepacia
(strain ATCC 17760/ NCIB 9086 / R18194))
Length = 650
Score = 56.4 bits (130), Expect = 5e-07
Identities = 44/158 (27%), Positives = 76/158 (48%), Gaps = 5/158 (3%)
Frame = +2
Query: 128 YEKAQQRSLNDPEGFWGEVGSE--LEWTKPWDRVLDDSN-APFTKWWVGGEMSVCYN--A 292
Y++ + S+ +PE +W V E + W P +D S A F W+ GG+++ A
Sbjct: 34 YDELMRVSIAEPERYWDTVMRECAIAWDVPPTGYVDLSRGAQFPSWFPGGKLNWVNTIYA 93
Query: 293 VDRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMP 472
RH +Q A+V + +V +++ EL+ +V A L GV +G R+ + M
Sbjct: 94 WARHPATA--QQKAVVAERE-DGSVSTLTFAELEQRVQDFAAGLARHGVKQGDRIGLLME 150
Query: 473 LVPEAIIAMLATNRIGAIHSVVFGGFAARELXTRIEHA 586
EA +++LA +GA+ +F GF + R+ A
Sbjct: 151 NGVEATVSLLAIVHLGALVVPLFSGFGVDAIVARLSAA 188
>UniRef50_Q0SJB1 Cluster: Acetoacetate--CoA ligase; n=1; Rhodococcus
sp. RHA1|Rep: Acetoacetate--CoA ligase - Rhodococcus sp.
(strain RHA1)
Length = 666
Score = 56.4 bits (130), Expect = 5e-07
Identities = 44/159 (27%), Positives = 71/159 (44%), Gaps = 2/159 (1%)
Frame = +2
Query: 104 NVCGXTPEYEKAQQRSLNDPEGFWGEVGSELEW--TKPWDRVLDDSNAPFTKWWVGGEMS 277
NVC T +++ S++D E FW + + + P VL D P +W+ G ++
Sbjct: 34 NVC--TTDFDSLWCWSISDLEKFWLSIWEYFDVIASAPPQTVLSDPRMPGARWFPGTRLN 91
Query: 278 VCYNAVDRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARV 457
N + RH + G V + T T ++S EL QV+ LA +GV G R+
Sbjct: 92 WAENLL-RHT-DRTGPAIISVDE---TGTTGELSRAELVAQVANLAAHFRKIGVQPGDRI 146
Query: 458 LIYMPLVPEAIIAMLATNRIGAIHSVVFGGFAARELXTR 574
+P + + A+LA +GA+ S F + L R
Sbjct: 147 AAMLPNIAPTVAAVLAAASVGAVWSCCAPDFGVKGLVDR 185
>UniRef50_Q5KW92 Cluster: Acetyl-CoA synthetase; n=2;
Geobacillus|Rep: Acetyl-CoA synthetase - Geobacillus
kaustophilus
Length = 552
Score = 56.0 bits (129), Expect = 6e-07
Identities = 30/107 (28%), Positives = 57/107 (53%)
Frame = +2
Query: 266 GEMSVCYNAVDRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSK 445
G + + DR+ + + AL +++ L + + I+Y +L+D +++A LGV K
Sbjct: 29 GRFNAAHEVCDRYAEDPN--RIALFYENALGEQ-KTITYRQLRDWSNQMANVFRKLGVKK 85
Query: 446 GARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFAARELXTRIEHA 586
G RV MP P ++ +LA ++GA++ +F F + + RI H+
Sbjct: 86 GDRVCALMPKNPALVVYILAAWKVGAVYVPLFTAFGPQAIEYRINHS 132
>UniRef50_Q2J785 Cluster: Acetoacetyl-CoA synthase; n=5;
Actinobacteria (class)|Rep: Acetoacetyl-CoA synthase -
Frankia sp. (strain CcI3)
Length = 709
Score = 55.6 bits (128), Expect = 8e-07
Identities = 40/130 (30%), Positives = 63/130 (48%), Gaps = 2/130 (1%)
Frame = +2
Query: 149 SLNDPEGFWGEVGS--ELEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDRHVVNGRG 322
S+ D + FW + +E + L D+ P W+ G ++ NA+ R G
Sbjct: 71 SVTDLDTFWESIWDFCAVEGDRGTGPALADAAMPGAVWFPGARVNYAENALTRR---GPA 127
Query: 323 EQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAML 502
V + T V S++EL+ QV++ A L +LGV++G RV +P A++ ML
Sbjct: 128 PAVIAVREDGATAVV---SWDELRRQVAKAAAGLRSLGVAEGDRVCAVLPNTVYAMVGML 184
Query: 503 ATNRIGAIHS 532
AT IGA+ S
Sbjct: 185 ATASIGAVWS 194
>UniRef50_Q7WPR9 Cluster: AMP-binding enzyme; n=5;
Burkholderiales|Rep: AMP-binding enzyme - Bordetella
bronchiseptica (Alcaligenes bronchisepticus)
Length = 649
Score = 55.2 bits (127), Expect = 1e-06
Identities = 40/157 (25%), Positives = 72/157 (45%), Gaps = 4/157 (2%)
Frame = +2
Query: 128 YEKAQQRSLNDPEGFWGEVGSE--LEWTKPWDRVLDDSNAP-FTKWWVGGEMSVCYNAVD 298
Y+ + S+ +PE +W V E + W +P +D + P F W+ GG ++ N +
Sbjct: 35 YDDLMRVSVEEPERYWNTVMRECAIAWDEPPTGYVDLARGPQFPSWFPGGRLN-WVNTIY 93
Query: 299 RHVVN-GRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPL 475
N Q A++ + +V ++Y EL+ +V A L G G R+ + M
Sbjct: 94 AWARNPATAGQTAVIGERE-DGSVGSLTYQELETRVREFAAGLARHGARPGDRIGLLMEN 152
Query: 476 VPEAIIAMLATNRIGAIHSVVFGGFAARELXTRIEHA 586
+A +++LA +GA+ +F GF + R+ A
Sbjct: 153 GVDATVSLLAIVHLGALVVPLFSGFGVDAIVARLSAA 189
>UniRef50_A3JB96 Cluster: Acetyl-coenzyme A synthetase; n=6;
Gammaproteobacteria|Rep: Acetyl-coenzyme A synthetase -
Marinobacter sp. ELB17
Length = 668
Score = 54.8 bits (126), Expect = 1e-06
Identities = 42/142 (29%), Positives = 66/142 (46%), Gaps = 2/142 (1%)
Frame = +2
Query: 113 GXTPEYEKAQQRSLNDPEGFWGEVGSE--LEWTKPWDRVLDDSNAPFTKWWVGGEMSVCY 286
G +Y + + S++D EGFW V L P +VL + P +W+ G ++
Sbjct: 36 GPFADYHELHEWSVSDLEGFWRAVWDYCGLISHTPAQKVLGKRDMPGAEWFPGMTLNFAA 95
Query: 287 NAVDRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIY 466
N + RH + A+V +R+ +Y EL+ V L L + GV KG RV
Sbjct: 96 NLL-RHAEGEQANSEAIVAYCETRPVLRR-TYTELRADVGALEAYLCSQGVIKGDRVAGI 153
Query: 467 MPLVPEAIIAMLATNRIGAIHS 532
+ EA++ MLA +GA+ S
Sbjct: 154 VTNGYEAMVGMLAATSMGALWS 175
>UniRef50_Q5P869 Cluster: 3-hydroxybenzoate CoA ligase; n=2;
Rhodocyclaceae|Rep: 3-hydroxybenzoate CoA ligase -
Azoarcus sp. (strain EbN1) (Aromatoleum aromaticum
(strain EbN1))
Length = 523
Score = 53.2 bits (122), Expect = 4e-06
Identities = 37/105 (35%), Positives = 50/105 (47%)
Frame = +2
Query: 266 GEMSVCYNAVDRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSK 445
G M+ + R + G GEQ A+V R +SY EL V+R L GV++
Sbjct: 10 GTMNAADEIIGRPLSLGLGEQAAIVSGE------RSVSYRELNAMVNRTGNALKEHGVAR 63
Query: 446 GARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFAARELXTRIE 580
G RVL M PE + A L T RIGA+ + A R++ IE
Sbjct: 64 GERVLFLMDDSPEMVAAYLGTLRIGAVSVALNVRLAPRDVRYVIE 108
>UniRef50_A4FEF5 Cluster: AMP-dependent synthetase and ligase; n=4;
Bacteria|Rep: AMP-dependent synthetase and ligase -
Saccharopolyspora erythraea (strain NRRL 23338)
Length = 571
Score = 53.2 bits (122), Expect = 4e-06
Identities = 27/73 (36%), Positives = 42/73 (57%)
Frame = +2
Query: 368 RKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGG 547
R+I+Y EL + +R AG L +GV+ G RV +++P P+ ++AML R GA++ V
Sbjct: 58 RRITYAELDELAARFAGWLDAVGVAPGERVGVFLPNCPQLVVAMLGVLRAGAVYVPVNPM 117
Query: 548 FAARELXTRIEHA 586
F EL + A
Sbjct: 118 FREHELRHELADA 130
>UniRef50_Q8YBS1 Cluster: ACETYL-COENZYME A SYNTHETASE; n=38;
Proteobacteria|Rep: ACETYL-COENZYME A SYNTHETASE -
Brucella melitensis
Length = 568
Score = 52.8 bits (121), Expect = 6e-06
Identities = 27/101 (26%), Positives = 50/101 (49%)
Frame = +2
Query: 272 MSVCYNAVDRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGA 451
++ C DR+ GE +H + +T+ ++++ +L+D +R+ L G+S G
Sbjct: 50 INACIECCDRYT----GENRVALHAISIDNTLTELTFEDLRDMSARVGNMLADAGISAGD 105
Query: 452 RVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFAARELXTR 574
V +P PE + +L RIGAI+ +F F + + R
Sbjct: 106 VVAGLLPRTPELVATILGAWRIGAIYQPLFTAFGPKAIEQR 146
>UniRef50_A6FGF6 Cluster: Probable AMP-binding enzyme; n=1;
Moritella sp. PE36|Rep: Probable AMP-binding enzyme -
Moritella sp. PE36
Length = 743
Score = 52.8 bits (121), Expect = 6e-06
Identities = 25/54 (46%), Positives = 38/54 (70%)
Frame = +2
Query: 371 KISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHS 532
++SY +L+++V+R+A + LG+ KG RV +P EA++AMLAT IGAI S
Sbjct: 137 QLSYLQLREEVTRIAAAMRELGIVKGDRVAGLLPNCSEAVVAMLATTSIGAIWS 190
>UniRef50_A0KEL2 Cluster: Acetoacetyl-CoA synthase; n=2;
Aeromonas|Rep: Acetoacetyl-CoA synthase - Aeromonas
hydrophila subsp. hydrophila (strain ATCC 7966 / NCIB
9240)
Length = 645
Score = 52.8 bits (121), Expect = 6e-06
Identities = 24/51 (47%), Positives = 35/51 (68%)
Frame = +2
Query: 374 ISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAI 526
+S+ EL DQV+RLA L G+ +G V Y+P +P+ ++AMLAT +GAI
Sbjct: 115 LSWRELADQVARLAQWLRGQGIGRGDVVAAYLPNIPQTVVAMLATTSLGAI 165
>UniRef50_Q83DG9 Cluster: Acetoacetyl-CoA synthase; n=5;
Gammaproteobacteria|Rep: Acetoacetyl-CoA synthase -
Coxiella burnetii
Length = 650
Score = 51.2 bits (117), Expect = 2e-05
Identities = 46/152 (30%), Positives = 69/152 (45%), Gaps = 3/152 (1%)
Frame = +2
Query: 128 YEKAQQRSLNDPEGFWGEVGSELEWTK---PWDRVLDDSNAPFTKWWVGGEMSVCYNAVD 298
Y Q S++ P FW V + P + ++ ++W++G +++ N +
Sbjct: 38 YPALYQWSIDQPALFWKAVWDFCGISASQAPTNVLVRGKRMEESQWFLGAKLNFAENLL- 96
Query: 299 RHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLV 478
RH R + AL+ S T R I+Y EL +V+ LAG L V G RV+ +
Sbjct: 97 RH----RNQNVALIFTSE-TGFSRSITYAELYTEVAALAGFLRQCHVVPGDRVVGVLSNQ 151
Query: 479 PEAIIAMLATNRIGAIHSVVFGGFAARELXTR 574
E +IAMLAT +GAI S F L R
Sbjct: 152 IETVIAMLATASVGAIWSACSPDFGLEGLVDR 183
>UniRef50_A2SSU3 Cluster: AMP-dependent synthetase and ligase; n=3;
Methanocorpusculum labreanum Z|Rep: AMP-dependent
synthetase and ligase - Methanocorpusculum labreanum
(strain ATCC 43576 / DSM 4855 / Z)
Length = 571
Score = 51.2 bits (117), Expect = 2e-05
Identities = 28/69 (40%), Positives = 39/69 (56%)
Frame = +2
Query: 374 ISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFA 553
ISY L +QV A L GV KG V I++P +P+++IA A NRIGA+ ++V
Sbjct: 58 ISYRSLMEQVHACAAGLMQHGVKKGDFVTIFLPNIPQSVIAAYAVNRIGAVCNLVHPLST 117
Query: 554 ARELXTRIE 580
EL +E
Sbjct: 118 KDELRYAVE 126
>UniRef50_UPI0000510398 Cluster: COG0365: Acyl-coenzyme A
synthetases/AMP-(fatty) acid ligases; n=1;
Brevibacterium linens BL2|Rep: COG0365: Acyl-coenzyme A
synthetases/AMP-(fatty) acid ligases - Brevibacterium
linens BL2
Length = 597
Score = 50.8 bits (116), Expect = 2e-05
Identities = 33/120 (27%), Positives = 54/120 (45%)
Frame = +2
Query: 164 EGFWGEVGSELEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDRHVVNGRGEQFALVH 343
E W + + L+W D + T W+ G + +N + RH+ + ++ AL
Sbjct: 10 ESNWRPIINTLDWEVEPDELFRPDPTGGT-WFPGARIDALHNLLLRHL-DTHSDRLALHW 67
Query: 344 DSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGA 523
+ D ++Y EL D V+ L LGV G RV ++ +P +AMLA +GA
Sbjct: 68 EGEPGDR-ESLTYRELADDVATFTAALQKLGVGAGDRVALHTGWLPSTAVAMLACTGLGA 126
>UniRef50_A6QV87 Cluster: Putative uncharacterized protein; n=2;
Pezizomycotina|Rep: Putative uncharacterized protein -
Ajellomyces capsulatus NAm1
Length = 747
Score = 50.8 bits (116), Expect = 2e-05
Identities = 42/142 (29%), Positives = 71/142 (50%), Gaps = 5/142 (3%)
Frame = +2
Query: 128 YEKAQQRSLNDPEGFWGEVG--SELEWTKPWDRVLDDSNAPFTK--WWVGGEMSVCYNAV 295
Y + S+++P FW E+ + ++ K +D+VLD F K ++ G ++ N +
Sbjct: 48 YHDLWEWSISEPSAFWEEIWYFTGVKAQKSYDKVLDKGTPLFPKPVFFKGSLLNFAENLL 107
Query: 296 DRHVVNGRGEQFALVHDSPLTDTVRK-ISYNELKDQVSRLAGKLTTLGVSKGARVLIYMP 472
+ GE + + T++ R+ IS+ +L+ +V R A L GV KG RV ++
Sbjct: 108 --FPASNPGENSVAIIAA--TESTREHISWKDLRARVHRCALSLREAGVVKGDRVAGFVG 163
Query: 473 LVPEAIIAMLATNRIGAIHSVV 538
+IAMLA IGA+ S V
Sbjct: 164 NHANTVIAMLAATSIGALWSSV 185
>UniRef50_A7I4G3 Cluster: AMP-dependent synthetase and ligase; n=1;
Candidatus Methanoregula boonei 6A8|Rep: AMP-dependent
synthetase and ligase - Methanoregula boonei (strain
6A8)
Length = 519
Score = 50.4 bits (115), Expect = 3e-05
Identities = 26/63 (41%), Positives = 38/63 (60%)
Frame = +2
Query: 377 SYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFAA 556
SY EL+D+++R+ L+ LG+ KG RV IY+ PE +I+ A RIGA+ + A
Sbjct: 30 SYRELRDEMNRIGCGLSGLGIQKGDRVCIYLDSSPEYLISYFAIWRIGAVAVPANSVYQA 89
Query: 557 REL 565
EL
Sbjct: 90 EEL 92
>UniRef50_P27096 Cluster: Uncharacterized 16.9 kDa protein in acs
3'region; n=1; Methanosaeta concilii|Rep:
Uncharacterized 16.9 kDa protein in acs 3'region -
Methanothrix soehngenii
Length = 145
Score = 50.0 bits (114), Expect = 4e-05
Identities = 20/46 (43%), Positives = 29/46 (63%), Gaps = 1/46 (2%)
Frame = +2
Query: 170 FWGEVGSEL-EWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDRH 304
FWGE+ +W +PW L+ P+ KW+VGG+ +V +N VDRH
Sbjct: 87 FWGEMAKTYADWFEPWSSTLE-WKPPYAKWFVGGKCNVTHNCVDRH 131
>UniRef50_Q47NR9 Cluster: Non-ribosomal peptide synthase:Amino acid
adenylation; n=1; Thermobifida fusca YX|Rep:
Non-ribosomal peptide synthase:Amino acid adenylation -
Thermobifida fusca (strain YX)
Length = 3629
Score = 49.6 bits (113), Expect = 5e-05
Identities = 26/63 (41%), Positives = 35/63 (55%)
Frame = +2
Query: 377 SYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFAA 556
SY L +V RLAG L GV G V + +P VPE + A+LA R+GA++ + F A
Sbjct: 2008 SYARLDAEVERLAGLLVAGGVRPGQVVAVLLPRVPELVAALLAVQRVGAVYVPLDPDFPA 2067
Query: 557 REL 565
L
Sbjct: 2068 ERL 2070
Score = 49.6 bits (113), Expect = 5e-05
Identities = 26/63 (41%), Positives = 35/63 (55%)
Frame = +2
Query: 377 SYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFAA 556
SY L +V RLAG L GV G V + +P VPE + A+LA R+GA++ + F A
Sbjct: 3054 SYARLDAEVERLAGLLVAGGVRPGQVVAVLLPRVPELVAALLAVQRVGAVYVPLDPDFPA 3113
Query: 557 REL 565
L
Sbjct: 3114 ERL 3116
>UniRef50_A5UV13 Cluster: AMP-dependent synthetase and ligase; n=7;
Bacteria|Rep: AMP-dependent synthetase and ligase -
Roseiflexus sp. RS-1
Length = 591
Score = 49.6 bits (113), Expect = 5e-05
Identities = 28/65 (43%), Positives = 36/65 (55%)
Frame = +2
Query: 371 KISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGF 550
K++Y +L + V R A L LGV KG RV + +P P +IA A RIGAI +
Sbjct: 63 KMTYQKLSEMVDRFANALYQLGVRKGDRVALMLPNSPHYVIAFFAAMRIGAIIVNNNPTY 122
Query: 551 AAREL 565
AREL
Sbjct: 123 TAREL 127
>UniRef50_A1SEZ8 Cluster: AMP-dependent synthetase and ligase; n=1;
Nocardioides sp. JS614|Rep: AMP-dependent synthetase and
ligase - Nocardioides sp. (strain BAA-499 / JS614)
Length = 541
Score = 49.6 bits (113), Expect = 5e-05
Identities = 32/83 (38%), Positives = 44/83 (53%)
Frame = +2
Query: 332 ALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATN 511
ALV +P D ++S+ L D SRLAG L LGV G RV + +P E IA+LAT
Sbjct: 45 ALVVVAP--DRTTEVSFGRLDDLSSRLAGVLRGLGVGVGDRVAVKLPQSAEMAIAVLATL 102
Query: 512 RIGAIHSVVFGGFAARELXTRIE 580
++GA+ V + R+E
Sbjct: 103 KLGAVVVTVSNVLGVDAVAHRLE 125
>UniRef50_A0Y863 Cluster: Long-chain fatty acid--CoA ligase; n=1;
marine gamma proteobacterium HTCC2143|Rep: Long-chain
fatty acid--CoA ligase - marine gamma proteobacterium
HTCC2143
Length = 558
Score = 49.6 bits (113), Expect = 5e-05
Identities = 38/121 (31%), Positives = 64/121 (52%), Gaps = 3/121 (2%)
Frame = +2
Query: 233 SNAPFTKWW-VGGEMSVCYNAVDRHVVNGRGEQFALVH-DSPLTDTV-RKISYNELKDQV 403
SN P W V E+ V +++ + G + +A + D+P R I+Y EL +
Sbjct: 4 SNNPQLPWQHVYDELKVVVPSLECGPLAGYVDDYASSNPDAPALQYFDRCITYIELNCEA 63
Query: 404 SRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFAARELXTRIEH 583
+RLA L +LGVSK V +++ +P+ +IA++A ++IG S V + EL ++E
Sbjct: 64 NRLANALVSLGVSKDDVVGMHLVNIPQYVIALVAVSKIGCAGSGVSPLMSPNELAYQVED 123
Query: 584 A 586
A
Sbjct: 124 A 124
>UniRef50_A0LK08 Cluster: AMP-dependent synthetase and ligase; n=1;
Syntrophobacter fumaroxidans MPOB|Rep: AMP-dependent
synthetase and ligase - Syntrophobacter fumaroxidans
(strain DSM 10017 / MPOB)
Length = 549
Score = 49.6 bits (113), Expect = 5e-05
Identities = 35/99 (35%), Positives = 55/99 (55%)
Frame = +2
Query: 269 EMSVCYNAVDRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKG 448
E+++ +DRHV +GRG++ A+ D V I+Y+EL+ V+R L G+
Sbjct: 30 ELNLADYLLDRHVRDGRGDRPAV----KFVDQV--ITYSELQRLVNRFGSSLRDAGLEAR 83
Query: 449 ARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFAAREL 565
RV I + PEAII++LA ++GAI +AA E+
Sbjct: 84 DRVGIRLVNCPEAIISVLAVEKLGAIPVPTSPLWAAEEI 122
>UniRef50_Q6MYU7 Cluster: Acetoacetyl-coa synthetase, putative; n=6;
Pezizomycotina|Rep: Acetoacetyl-coa synthetase, putative
- Aspergillus fumigatus (Sartorya fumigata)
Length = 699
Score = 49.6 bits (113), Expect = 5e-05
Identities = 38/145 (26%), Positives = 69/145 (47%), Gaps = 4/145 (2%)
Frame = +2
Query: 101 YNVCGXTPEYEKAQQRSLNDPEGFWGEVG--SELEWTKPWDRVLDDSNAPFTK--WWVGG 268
Y +C Y+ Q S++ P FW E+ + ++ K +DRV+ F + ++ G
Sbjct: 41 YQLC--LQNYKDLWQWSISRPSEFWEEIWHYTNIKAHKQYDRVMSSEKLLFPRPHFFEGS 98
Query: 269 EMSVCYNAVDRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKG 448
+++ N + + + E V + +D +S+ EL+++V + A L G+ G
Sbjct: 99 KLNFAENLL--YPASSPAEDTTAVISATESDR-EFVSWKELRERVRKCANSLREAGLQAG 155
Query: 449 ARVLIYMPLVPEAIIAMLATNRIGA 523
RV ++ +IAMLAT IGA
Sbjct: 156 DRVAGFLGNHANTVIAMLATTSIGA 180
>UniRef50_Q3IUK7 Cluster: Acyl-CoA synthetase I 5; n=2;
Halobacteriaceae|Rep: Acyl-CoA synthetase I 5 -
Natronomonas pharaonis (strain DSM 2160 / ATCC 35678)
Length = 544
Score = 49.6 bits (113), Expect = 5e-05
Identities = 35/109 (32%), Positives = 53/109 (48%), Gaps = 3/109 (2%)
Frame = +2
Query: 227 DDSNAPFTKWWVGGEMSVCYNAVDRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVS 406
+ + A FT W + + + Y+ V +H R F D + S+ +L D+
Sbjct: 13 EQATAEFT-WDIPNDYNAAYDLVGKHEHADRPALFQAYPDGRREE----YSFGDLDDESD 67
Query: 407 RLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIH---SVVFG 544
RLA L LGV +G RV + +P VP I LA ++GA+ SV+FG
Sbjct: 68 RLANALADLGVGRGDRVGVVLPQVPANPITHLACWKLGAVSMPLSVLFG 116
>UniRef50_UPI000038E2AC Cluster: hypothetical protein Faci_03000151;
n=1; Ferroplasma acidarmanus fer1|Rep: hypothetical
protein Faci_03000151 - Ferroplasma acidarmanus fer1
Length = 646
Score = 48.8 bits (111), Expect = 9e-05
Identities = 42/151 (27%), Positives = 73/151 (48%), Gaps = 2/151 (1%)
Frame = +2
Query: 128 YEKAQQRSLNDPEGFWGEVG--SELEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDR 301
Y++ + S+ +PE FW + S L+ + ++ +L ++N +W+ G + N DR
Sbjct: 39 YKELWEWSVKNPEIFWISLADFSGLDLGE-YNSILSENNVN-ARWFEGARV----NYADR 92
Query: 302 HVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVP 481
V R + A + + I+Y+ L +VS LA + G++ V Y+ +P
Sbjct: 93 -VYRMRNIEKAAIISYNEEGKEQVITYHSLWQKVSSLAAYFQSNGIAASDTVCAYIGNIP 151
Query: 482 EAIIAMLATNRIGAIHSVVFGGFAARELXTR 574
EA+I +LAT IGAI S F + + R
Sbjct: 152 EAVITLLATASIGAIWSSCSPDFGIKGVIER 182
>UniRef50_Q8G3C8 Cluster: Acetoacetyl-CoA synthase; n=36;
Proteobacteria|Rep: Acetoacetyl-CoA synthase - Brucella
suis
Length = 662
Score = 48.8 bits (111), Expect = 9e-05
Identities = 41/153 (26%), Positives = 70/153 (45%), Gaps = 2/153 (1%)
Frame = +2
Query: 122 PEYEKAQQRSLNDPEGFWGEVGS--ELEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAV 295
P+Y + S+ D GFW V + + + D + K++ ++ N +
Sbjct: 45 PDYAALHRWSVEDRAGFWQLVWDFCSVIGERGNTALTDRGHMRAAKFFPEARLNFAENLL 104
Query: 296 DRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPL 475
RH G GE ++ + R++++N+L VS+L + + GV G RV MP
Sbjct: 105 -RH--KGDGEAIVFRGENKVE---RRLTWNDLHALVSKLQQFMLSEGVQPGDRVAGMMPN 158
Query: 476 VPEAIIAMLATNRIGAIHSVVFGGFAARELXTR 574
+PEA+ MLA + IGA+ S F + + R
Sbjct: 159 MPEAVALMLAASSIGAVWSSCSPDFGVQGVLDR 191
>UniRef50_Q11M02 Cluster: Acetoacetyl-CoA synthase; n=7;
Proteobacteria|Rep: Acetoacetyl-CoA synthase -
Mesorhizobium sp. (strain BNC1)
Length = 652
Score = 48.8 bits (111), Expect = 9e-05
Identities = 28/69 (40%), Positives = 37/69 (53%)
Frame = +2
Query: 368 RKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGG 547
R+IS++ELK VSRL GV G R+ MP +PE + AMLA +GA+ S
Sbjct: 114 RRISWHELKALVSRLQQLFKAEGVKAGDRIAGMMPNMPETVAAMLAAASLGAVWSSCSPD 173
Query: 548 FAARELXTR 574
F R + R
Sbjct: 174 FGVRGVLDR 182
>UniRef50_Q7WNN5 Cluster: Putative long-chain-fatty-acid-CoA ligase;
n=5; Bordetella|Rep: Putative long-chain-fatty-acid-CoA
ligase - Bordetella bronchiseptica (Alcaligenes
bronchisepticus)
Length = 539
Score = 48.4 bits (110), Expect = 1e-04
Identities = 27/71 (38%), Positives = 38/71 (53%)
Frame = +2
Query: 374 ISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFA 553
+SY+ L V A L LGV +G RV + P PEAII LA R+GA+ + +
Sbjct: 37 LSYSRLLAVVDEAAALLARLGVRRGDRVALLSPPRPEAIITFLACTRLGAVWLALNPKYK 96
Query: 554 ARELXTRIEHA 586
A E+ ++HA
Sbjct: 97 APEIHYILDHA 107
>UniRef50_Q39T59 Cluster: AMP-dependent synthetase and ligase; n=1;
Geobacter metallireducens GS-15|Rep: AMP-dependent
synthetase and ligase - Geobacter metallireducens
(strain GS-15 / ATCC 53774 / DSM 7210)
Length = 539
Score = 48.4 bits (110), Expect = 1e-04
Identities = 28/91 (30%), Positives = 43/91 (47%)
Frame = +2
Query: 314 GRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAII 493
GRG++ A+ +P + R ++NEL R A L +LGV G Y+P PE +
Sbjct: 22 GRGDRVAMRWLTPGMER-RDYTFNELDGLSGRFANVLASLGVGAGEVFFTYLPKQPEQFV 80
Query: 494 AMLATNRIGAIHSVVFGGFAARELXTRIEHA 586
A L ++ A+ +F F L R+ A
Sbjct: 81 AFLGALKLTAVAGTLFSNFGEEALLDRLADA 111
>UniRef50_A0LLK9 Cluster: Benzoate-CoA ligase family; n=1;
Syntrophobacter fumaroxidans MPOB|Rep: Benzoate-CoA
ligase family - Syntrophobacter fumaroxidans (strain DSM
10017 / MPOB)
Length = 513
Score = 48.4 bits (110), Expect = 1e-04
Identities = 33/102 (32%), Positives = 51/102 (50%)
Frame = +2
Query: 218 RVLDDSNAPFTKWWVGGEMSVCYNAVDRHVVNGRGEQFALVHDSPLTDTVRKISYNELKD 397
R + D+ AP V +V +D H + R ++ A+ H + ISY +L+
Sbjct: 3 RFVRDAAAPGRNNAVKSFYNVACELIDGHA-DARPDKTAIYHGA------ETISYRQLRV 55
Query: 398 QVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGA 523
+++R L LGVS G R+LI +P PE +IA L + GA
Sbjct: 56 RINRFGNVLRGLGVSPGERILIALPDCPECVIAFLGGIKCGA 97
>UniRef50_Q2H9I4 Cluster: Putative uncharacterized protein; n=1;
Chaetomium globosum|Rep: Putative uncharacterized
protein - Chaetomium globosum (Soil fungus)
Length = 438
Score = 48.4 bits (110), Expect = 1e-04
Identities = 34/138 (24%), Positives = 72/138 (52%), Gaps = 4/138 (2%)
Frame = +2
Query: 125 EYEKAQQRSLNDPEGFWGEVG--SELEWTKPWDRVLDDSNAPFTK--WWVGGEMSVCYNA 292
+Y + + S+++ FWG+V + ++ +KP+D+VL F + ++ G ++ N
Sbjct: 34 DYPQLYKWSVDNVADFWGDVWHFAGIKASKPFDQVLPSEAPMFPRPDFFAGARLNFAENL 93
Query: 293 VDRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMP 472
+ V A++ + + + + S+ EL+DQV R + L +GV + + V ++
Sbjct: 94 LFPANVEIDESTTAVITATENDNHLVETSWAELRDQVRRCSNALRAIGVKENSVVAGFVA 153
Query: 473 LVPEAIIAMLATNRIGAI 526
+A++A+L+ IGAI
Sbjct: 154 NHVQALVALLSAATIGAI 171
>UniRef50_Q13BW2 Cluster: AMP-dependent synthetase and ligase; n=4;
Rhizobiales|Rep: AMP-dependent synthetase and ligase -
Rhodopseudomonas palustris (strain BisB5)
Length = 548
Score = 48.0 bits (109), Expect = 2e-04
Identities = 24/53 (45%), Positives = 34/53 (64%)
Frame = +2
Query: 368 RKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAI 526
R +SY EL Q+ R+A LT LGV++G RV +++ E + LA NRIGA+
Sbjct: 55 RTLSYRELDAQMRRIAASLTGLGVARGDRVALFLGNCWEFLACTLACNRIGAL 107
>UniRef50_Q0SGL4 Cluster: AMP-dependent synthetase; n=1; Rhodococcus
sp. RHA1|Rep: AMP-dependent synthetase - Rhodococcus sp.
(strain RHA1)
Length = 506
Score = 48.0 bits (109), Expect = 2e-04
Identities = 21/51 (41%), Positives = 32/51 (62%)
Frame = +2
Query: 374 ISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAI 526
++Y +L+D +R AG LT G+S G+RVL+ P VPE ++A L G +
Sbjct: 28 LTYGQLRDASTRYAGALTRAGLSPGSRVLLAAPSVPEFVVAYLGIQAAGCV 78
>UniRef50_Q6A9A4 Cluster: Acetyl-coenzyme A synthetase; n=1;
Propionibacterium acnes|Rep: Acetyl-coenzyme A
synthetase - Propionibacterium acnes
Length = 222
Score = 47.6 bits (108), Expect = 2e-04
Identities = 22/42 (52%), Positives = 28/42 (66%)
Frame = +2
Query: 410 LAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSV 535
+A L +GV KG V IY+P +PE AMLA +IGA+HSV
Sbjct: 1 MANVLKVMGVRKGDVVTIYLPRIPEIFFAMLACAKIGAVHSV 42
>UniRef50_UPI000038CCA4 Cluster: COG0318: Acyl-CoA synthetases
(AMP-forming)/AMP-acid ligases II; n=1; Nostoc
punctiforme PCC 73102|Rep: COG0318: Acyl-CoA synthetases
(AMP-forming)/AMP-acid ligases II - Nostoc punctiforme
PCC 73102
Length = 1034
Score = 47.2 bits (107), Expect = 3e-04
Identities = 26/75 (34%), Positives = 39/75 (52%)
Frame = +2
Query: 362 TVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVF 541
T R I+Y +L + + ++A L G SKG + IY P +PE IA A +G I + V
Sbjct: 39 TNRIITYKQLVESIRKIACSLAARGFSKGDVLAIYSPNIPEYAIAFHAVATLGGIITTVN 98
Query: 542 GGFAARELXTRIEHA 586
+ A EL ++ A
Sbjct: 99 PSYTAEELAYQLNDA 113
>UniRef50_Q0S7A8 Cluster: 2,3-dihydroxybenzoate-AMP ligase/
S-dihydroxybenzoyltransferase; n=6; Bacteria|Rep:
2,3-dihydroxybenzoate-AMP ligase/
S-dihydroxybenzoyltransferase - Rhodococcus sp. (strain
RHA1)
Length = 550
Score = 47.2 bits (107), Expect = 3e-04
Identities = 29/89 (32%), Positives = 45/89 (50%), Gaps = 3/89 (3%)
Frame = +2
Query: 308 VNGRGEQF--ALVHDSPLTDTV-RKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLV 478
+ R EQF A+ P V R ++Y EL D+ RLA L + GV G RV++ +P +
Sbjct: 38 LGARAEQFGDAIAVTGPDASGVDRALTYRELSDRADRLAAGLQSSGVQPGDRVVVQLPNI 97
Query: 479 PEAIIAMLATNRIGAIHSVVFGGFAAREL 565
E + + A R+GA+ A+E+
Sbjct: 98 VEYVEVIFAVFRLGALPVFALPAHRAQEI 126
>UniRef50_Q18HL6 Cluster: O-succinylbenzoic acid--CoA ligase; n=1;
Haloquadratum walsbyi DSM 16790|Rep: O-succinylbenzoic
acid--CoA ligase - Haloquadratum walsbyi (strain DSM
16790)
Length = 506
Score = 47.2 bits (107), Expect = 3e-04
Identities = 28/76 (36%), Positives = 41/76 (53%)
Frame = +2
Query: 359 DTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVV 538
+T ++ L V RLAG+L TLGVS+G R+ I + E+++ A RIGA +
Sbjct: 22 ETGDNYTFAALDQAVERLAGRLITLGVSQGDRLGIVLSPRVESVLIFYAAARIGATAVPL 81
Query: 539 FGGFAARELXTRIEHA 586
A E+ TR+ HA
Sbjct: 82 GHRLTATEIETRLTHA 97
>UniRef50_Q87H07 Cluster: Acetyl-CoA synthase; n=13;
Vibrionales|Rep: Acetyl-CoA synthase - Vibrio
parahaemolyticus
Length = 677
Score = 46.8 bits (106), Expect = 4e-04
Identities = 24/53 (45%), Positives = 34/53 (64%)
Frame = +2
Query: 368 RKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAI 526
+++S +L +QVS + L GV KG V Y+P +PE +IAMLAT +GAI
Sbjct: 129 KQLSGQQLIEQVSIVQQWLIANGVGKGDVVAAYLPYLPETVIAMLATTSLGAI 181
>UniRef50_Q5KZW0 Cluster: Long-chain fatty-acid-CoA ligase; n=6;
Bacillaceae|Rep: Long-chain fatty-acid-CoA ligase -
Geobacillus kaustophilus
Length = 511
Score = 46.8 bits (106), Expect = 4e-04
Identities = 24/71 (33%), Positives = 38/71 (53%)
Frame = +2
Query: 374 ISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFA 553
+SY E+ V+RLA L LGV +G +V +YMP E ++ A R+GA+ +
Sbjct: 27 LSYAEVNCMVNRLASSLARLGVGRGDKVALYMPNTKEFAVSYFAVLRLGAVVVPINARLT 86
Query: 554 ARELXTRIEHA 586
A E+ + H+
Sbjct: 87 AAEVQYILGHS 97
>UniRef50_Q3IWF1 Cluster: AMP-binding enzyme; n=6;
Alphaproteobacteria|Rep: AMP-binding enzyme -
Rhodobacter sphaeroides (strain ATCC 17023 / 2.4.1 /
NCIB 8253 / DSM158)
Length = 554
Score = 46.8 bits (106), Expect = 4e-04
Identities = 22/64 (34%), Positives = 37/64 (57%)
Frame = +2
Query: 374 ISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFA 553
++Y E++ +V+ LA +L LG+ KG V + +P V + LA RIGA+ + G+
Sbjct: 56 LTYGEMRRKVNGLAARLVALGIGKGTHVGVMLPNVEAFPLTWLALGRIGAVMLPINPGYT 115
Query: 554 AREL 565
RE+
Sbjct: 116 PREI 119
>UniRef50_Q2BI30 Cluster: Acetyl-coenzyme A synthetase; n=1;
Neptuniibacter caesariensis|Rep: Acetyl-coenzyme A
synthetase - Neptuniibacter caesariensis
Length = 73
Score = 46.8 bits (106), Expect = 4e-04
Identities = 19/51 (37%), Positives = 30/51 (58%), Gaps = 3/51 (5%)
Frame = +2
Query: 125 EYEKAQQRSLNDPEGFWGEVGSELEWTKPWDRVLDDSNAPFT---KWWVGG 268
+Y ++S+NDPE FWGE G ++W KP+ +V + S P +W+ G
Sbjct: 22 KYLAMYEQSVNDPEAFWGEAGKRIDWFKPYTKVKNTSFDPHNVDIRWYEDG 72
>UniRef50_A1UDV2 Cluster: AMP-dependent synthetase and ligase; n=8;
Mycobacterium|Rep: AMP-dependent synthetase and ligase -
Mycobacterium sp. (strain KMS)
Length = 518
Score = 46.8 bits (106), Expect = 4e-04
Identities = 28/73 (38%), Positives = 41/73 (56%), Gaps = 1/73 (1%)
Frame = +2
Query: 371 KISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGF 550
++ Y + + + +RLA L LG KG V + P E ++ MLA RIGA+ V F F
Sbjct: 30 RLDYGQAERRSARLARGLLALGAGKGTHVGLLYPNGAEFLVGMLAAARIGAV-VVPFSTF 88
Query: 551 A-ARELXTRIEHA 586
A AREL ++ H+
Sbjct: 89 ATARELAEQLRHS 101
>UniRef50_Q0WQ54 Cluster: Acetyl-CoA synthetase-like protein; n=17;
Magnoliophyta|Rep: Acetyl-CoA synthetase-like protein -
Arabidopsis thaliana (Mouse-ear cress)
Length = 295
Score = 46.8 bits (106), Expect = 4e-04
Identities = 38/157 (24%), Positives = 71/157 (45%), Gaps = 6/157 (3%)
Frame = +2
Query: 128 YEKAQQRSLNDPEGFWGEVGSELE--WTKPWDRVLDDSNA---PFTKWWVGGEMSVCYNA 292
+ Q+ S+++PE +W V EL ++ P +L+ + P KW G ++ N
Sbjct: 115 FSSFQEFSVSNPEVYWKTVLDELNILFSVPPKCILEKDTSGDNPGGKWLPGAYLNPARNC 174
Query: 293 VDRHVVNGRGEQFALVHDSPLTDT-VRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYM 469
+ + D D V ++ EL+ QV A L+ LG+ + + + + M
Sbjct: 175 LTNGFKRRLDDIVIRWRDEGSDDLPVNTMTLLELRSQVWLAAHALSALGLEEESAIAVDM 234
Query: 470 PLVPEAIIAMLATNRIGAIHSVVFGGFAARELXTRIE 580
P+ E++I LA G + + F+ RE+ TR++
Sbjct: 235 PMNVESVIIYLAIVLAGHVVVSIADSFSPREISTRLK 271
>UniRef50_Q70C44 Cluster: Non-ribosomal peptide synthase; n=1;
Xanthomonas albilineans|Rep: Non-ribosomal peptide
synthase - Xanthomonas albilineans
Length = 941
Score = 46.4 bits (105), Expect = 5e-04
Identities = 22/54 (40%), Positives = 34/54 (62%)
Frame = +2
Query: 368 RKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIH 529
R++SY +L + +RLA L + GV GARV ++M PE + A+LA + GA +
Sbjct: 46 RRMSYGQLNTRANRLARLLQSQGVGPGARVAVWMNRSPECLAALLAVMKAGAAY 99
>UniRef50_Q0LLG2 Cluster: Amino acid adenylation; n=1; Herpetosiphon
aurantiacus ATCC 23779|Rep: Amino acid adenylation -
Herpetosiphon aurantiacus ATCC 23779
Length = 1413
Score = 46.4 bits (105), Expect = 5e-04
Identities = 34/90 (37%), Positives = 52/90 (57%), Gaps = 1/90 (1%)
Frame = +2
Query: 263 GGEMSVCYNAV-DRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGV 439
GGE+ + +V +R + N R + AL + +TDT ++SY EL V AG+L GV
Sbjct: 435 GGELRLPLTSVIERILHNARQQPHAL---ALVTDT-EQLSYAELASHVHAWAGQLVQRGV 490
Query: 440 SKGARVLIYMPLVPEAIIAMLATNRIGAIH 529
+ G+ V + +P EAI+A+LAT GA +
Sbjct: 491 TAGSVVGVALPRSREAIVAILATLCCGAAY 520
>UniRef50_Q2NH56 Cluster: Predicted acyl-CoA synthetase; n=1;
Methanosphaera stadtmanae DSM 3091|Rep: Predicted
acyl-CoA synthetase - Methanosphaera stadtmanae (strain
DSM 3091)
Length = 489
Score = 46.4 bits (105), Expect = 5e-04
Identities = 22/56 (39%), Positives = 35/56 (62%)
Frame = +2
Query: 359 DTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAI 526
D ++ + ++ +S + KL LG++KG RVLIY+P PE + + LA RIGA+
Sbjct: 24 DREKRYNSRDILGIISEIGRKLIDLGITKGDRVLIYLPNGPEYLFSFLALWRIGAV 79
>UniRef50_Q9Z3R3 Cluster: Acetoacetyl-coenzyme A synthetase; n=7;
Proteobacteria|Rep: Acetoacetyl-coenzyme A synthetase -
Rhizobium meliloti (Sinorhizobium meliloti)
Length = 650
Score = 46.4 bits (105), Expect = 5e-04
Identities = 24/54 (44%), Positives = 33/54 (61%)
Frame = +2
Query: 371 KISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHS 532
+++++EL+ VSRL L G+ G RV MP +PE I MLAT +GAI S
Sbjct: 115 RLTWDELRALVSRLQQALRAQGIGAGDRVAAMMPNMPETIALMLATASVGAIWS 168
>UniRef50_Q21UY9 Cluster: AMP-dependent synthetase and ligase; n=1;
Rhodoferax ferrireducens T118|Rep: AMP-dependent
synthetase and ligase - Rhodoferax ferrireducens (strain
DSM 15236 / ATCC BAA-621 / T118)
Length = 603
Score = 46.0 bits (104), Expect = 7e-04
Identities = 25/59 (42%), Positives = 38/59 (64%), Gaps = 3/59 (5%)
Frame = +2
Query: 377 SYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIH---SVVFG 544
+Y+EL+ Q +RL+ LT LGV +G RV I MP E +A +A ++GA+ S++FG
Sbjct: 68 TYSELQAQANRLSNVLTALGVGRGDRVAIVMPQCFETAVAYVAVLQMGAVAMPLSMLFG 126
>UniRef50_Q0RL93 Cluster: Putative uncharacterized protein; n=1;
Frankia alni ACN14a|Rep: Putative uncharacterized
protein - Frankia alni (strain ACN14a)
Length = 551
Score = 46.0 bits (104), Expect = 7e-04
Identities = 26/73 (35%), Positives = 38/73 (52%)
Frame = +2
Query: 368 RKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGG 547
R+++Y E ++ + LAG+ GV K RV + P PE II LA RIGA+ +
Sbjct: 51 RRLTYGEADERSALLAGQFVAAGVGKATRVGMVFPNSPEFIIVWLAIVRIGAVAVPISTL 110
Query: 548 FAARELXTRIEHA 586
EL + I H+
Sbjct: 111 STGTELRSVIRHS 123
>UniRef50_A3PSP1 Cluster: AMP-dependent synthetase and ligase; n=18;
Corynebacterineae|Rep: AMP-dependent synthetase and
ligase - Mycobacterium sp. (strain JLS)
Length = 556
Score = 46.0 bits (104), Expect = 7e-04
Identities = 27/61 (44%), Positives = 37/61 (60%)
Frame = +2
Query: 344 DSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGA 523
D+ L R ++ EL D+V++LAG L+ GV G RVLI M E I + LA N++GA
Sbjct: 38 DTALRFMGRTTTWGELDDRVTKLAGALSRRGVGFGDRVLILMLNRTEFIESFLAVNKLGA 97
Query: 524 I 526
I
Sbjct: 98 I 98
>UniRef50_A2QQX9 Cluster: Contig An08c0110, complete genome; n=6;
Pezizomycotina|Rep: Contig An08c0110, complete genome -
Aspergillus niger
Length = 693
Score = 46.0 bits (104), Expect = 7e-04
Identities = 37/136 (27%), Positives = 64/136 (47%), Gaps = 4/136 (2%)
Frame = +2
Query: 128 YEKAQQRSLNDPEGFWGEVG--SELEWTKPWDRVLDDSNAPFTK--WWVGGEMSVCYNAV 295
Y Q S+++P FW +V + ++ K +DRVL F + ++ G ++ N +
Sbjct: 42 YNDLWQWSVSEPAKFWEDVWKYTSIQAHKSYDRVLRSDKLLFPRPNFFEGTRLNFAENLL 101
Query: 296 DRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPL 475
+ E V + D +++ EL+D+V R A L G+ +G RV ++
Sbjct: 102 --YPSTSPDENAVAVIAATEADR-EFVTWKELRDRVRRCANSLKVSGLQEGDRVAGFLGN 158
Query: 476 VPEAIIAMLATNRIGA 523
++AMLAT IGA
Sbjct: 159 HTNTVVAMLATASIGA 174
>UniRef50_Q7NVV9 Cluster: Synthetase CbsF; n=3; cellular
organisms|Rep: Synthetase CbsF - Chromobacterium
violaceum
Length = 2859
Score = 45.6 bits (103), Expect = 9e-04
Identities = 28/88 (31%), Positives = 41/88 (46%), Gaps = 1/88 (1%)
Frame = +2
Query: 326 QFALVHDSP-LTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAML 502
Q A D+P L D R +SY E + QV LAG+L GV G V + +P +A++
Sbjct: 2020 QAARTPDAPALLDEARALSYAETRAQVGHLAGRLAEAGVKPGDIVAVALPRSAHLSLALM 2079
Query: 503 ATNRIGAIHSVVFGGFAARELXTRIEHA 586
A GA + + G+ L + A
Sbjct: 2080 AAQEAGAAYLPLDTGYPDERLAYMVADA 2107
>UniRef50_Q939Z1 Cluster: Peptide synthetase; n=7;
Actinomycetales|Rep: Peptide synthetase - Amycolatopsis
balhimycina
Length = 3165
Score = 45.6 bits (103), Expect = 9e-04
Identities = 20/61 (32%), Positives = 37/61 (60%)
Frame = +2
Query: 374 ISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFA 553
++Y +L ++ RLAG+L + G+ +G RV + M + ++A+LA + GA + V G+
Sbjct: 35 LTYRQLDERAGRLAGRLASRGIRRGDRVAVVMDRSADLVVALLAVWKAGAAYVPVDAGYP 94
Query: 554 A 556
A
Sbjct: 95 A 95
>UniRef50_Q21E99 Cluster: Amino acid adenylation; n=2; Bacteria|Rep:
Amino acid adenylation - Saccharophagus degradans (strain
2-40 / ATCC 43961 / DSM 17024)
Length = 3111
Score = 45.6 bits (103), Expect = 9e-04
Identities = 29/106 (27%), Positives = 52/106 (49%)
Frame = +2
Query: 269 EMSVCYNAVDRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKG 448
E + +D H +G+ A+V + + RK +Y EL + +RLA L +G+ KG
Sbjct: 2279 ENKTIIDLIDGHSASGKD---AVVLPNEM-GKARKATYAELTAKSNRLAHNLQNMGIGKG 2334
Query: 449 ARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFAARELXTRIEHA 586
+ V + +P PE I+ +L + GA + + + A + + HA
Sbjct: 2335 SIVALCLPKSPELIMTLLGVLKAGAAYLPLDPDYPADRISYMLNHA 2380
>UniRef50_A4TVS6 Cluster: AMP-dependent synthetase and ligase; n=1;
Magnetospirillum gryphiswaldense|Rep: AMP-dependent
synthetase and ligase - Magnetospirillum gryphiswaldense
Length = 528
Score = 45.6 bits (103), Expect = 9e-04
Identities = 31/88 (35%), Positives = 43/88 (48%)
Frame = +2
Query: 308 VNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEA 487
V GR ++ ALV + +SY +L ++V RLA LT LGV +G+RVL+ +
Sbjct: 25 VRGRPDKIALVFSD------QPVSYADLAEEVRRLAAGLTGLGVGRGSRVLVLLKNCRAF 78
Query: 488 IIAMLATNRIGAIHSVVFGGFAARELXT 571
MLA GA+ V G L T
Sbjct: 79 AALMLAAAERGAVIVPVSAGLRGEALVT 106
>UniRef50_A7SU89 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 724
Score = 45.6 bits (103), Expect = 9e-04
Identities = 27/90 (30%), Positives = 42/90 (46%)
Frame = +2
Query: 269 EMSVCYNAVDRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKG 448
E + +DRH ++ + D + +++ E KDQ +A +L LGV +G
Sbjct: 2 EHKTLFQLLDRHTAECPNKEALVYRDEK--GNRKSLTFKEYKDQSQAIAARLLELGVVRG 59
Query: 449 ARVLIYMPLVPEAIIAMLATNRIGAIHSVV 538
VL+ +P E I +A RIGAI V
Sbjct: 60 DMVLVMLPSEFEFAIVEIALGRIGAIFVAV 89
>UniRef50_Q62F86 Cluster: AMP-binding domain protein; n=14;
Burkholderia|Rep: AMP-binding domain protein -
Burkholderia mallei (Pseudomonas mallei)
Length = 522
Score = 45.2 bits (102), Expect = 0.001
Identities = 22/53 (41%), Positives = 29/53 (54%)
Frame = +2
Query: 368 RKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAI 526
R++ Y +L V R A L + G++ G RV Y P E I+ MLA N GAI
Sbjct: 29 RRVRYAQLAADVRRAAAALASAGIAPGERVATYAPKAYETIVTMLAANLAGAI 81
>UniRef50_Q13I22 Cluster: Putative AMP-dependent synthetase and
ligase; n=1; Burkholderia xenovorans LB400|Rep: Putative
AMP-dependent synthetase and ligase - Burkholderia
xenovorans (strain LB400)
Length = 559
Score = 45.2 bits (102), Expect = 0.001
Identities = 30/96 (31%), Positives = 48/96 (50%)
Frame = +2
Query: 299 RHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLV 478
R +V G + ALV +++Y +L ++V LA +L GV +G +V + M
Sbjct: 48 RELVANHGNREALVGQG------ERMTYQQLGERVEALAARLIRTGVKRGEKVGVLMGNR 101
Query: 479 PEAIIAMLATNRIGAIHSVVFGGFAARELXTRIEHA 586
PE +I+ LA IGA+ + AREL + H+
Sbjct: 102 PEWVISALAITSIGAVLVSLNSWATARELAYLLSHS 137
>UniRef50_A0Z3I7 Cluster: Acyl-CoA synthase; n=1; marine gamma
proteobacterium HTCC2080|Rep: Acyl-CoA synthase - marine
gamma proteobacterium HTCC2080
Length = 195
Score = 45.2 bits (102), Expect = 0.001
Identities = 25/63 (39%), Positives = 36/63 (57%)
Frame = +2
Query: 377 SYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFAA 556
SY +L++QV+ LA L LG+ G RV I+ P E ++ LAT +IGAI + +
Sbjct: 49 SYQQLQEQVNSLAAGLLALGIQAGDRVGIWGPNSAEWVMVQLATAKIGAIMVCINPAYRT 108
Query: 557 REL 565
EL
Sbjct: 109 YEL 111
>UniRef50_Q5TF43 Cluster: Acyl-CoA synthetase short-chain family
member 1; n=7; Tetrapoda|Rep: Acyl-CoA synthetase
short-chain family member 1 - Homo sapiens (Human)
Length = 153
Score = 45.2 bits (102), Expect = 0.001
Identities = 25/88 (28%), Positives = 44/88 (50%), Gaps = 2/88 (2%)
Frame = +2
Query: 128 YEKAQQRSLNDPEGFWGEVGSE-LEWTKPWDRVLD-DSNAPFTKWWVGGEMSVCYNAVDR 301
Y ++ +P FWG + + L W P+ V D D + W++GG+++V N +D+
Sbjct: 58 YPALSAQAAREPAAFWGPLARDTLVWDTPYHTVWDCDFSTGKIGWFLGGQLNVSVNCLDQ 117
Query: 302 HVVNGRGEQFALVHDSPLTDTVRKISYN 385
H V E AL+ + T +I+Y+
Sbjct: 118 H-VRKSPESVALIWERDEPGTEVRITYS 144
>UniRef50_Q45R83 Cluster: Peptide synthetase; n=3; Actinobacteria
(class)|Rep: Peptide synthetase - Streptomyces fradiae
Length = 5246
Score = 44.8 bits (101), Expect = 0.002
Identities = 25/82 (30%), Positives = 40/82 (48%)
Frame = +2
Query: 341 HDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIG 520
H + D R++SY EL D+ +RLA L G V + +P PE I A++A + G
Sbjct: 4191 HAPAVRDGDRELSYAELNDRANRLARFLAARGAGPEDTVAVLLPRGPELITALVAVQKAG 4250
Query: 521 AIHSVVFGGFAARELXTRIEHA 586
A + + A + +E+A
Sbjct: 4251 AAYVPMDAELPAERIAHMLENA 4272
>UniRef50_Q24N89 Cluster: Putative uncharacterized protein; n=1;
Desulfitobacterium hafniense Y51|Rep: Putative
uncharacterized protein - Desulfitobacterium hafniense
(strain Y51)
Length = 557
Score = 44.8 bits (101), Expect = 0.002
Identities = 25/64 (39%), Positives = 35/64 (54%)
Frame = +2
Query: 374 ISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFA 553
I+Y E RLA + +G+ KG RV+I +P +PE +IA A +IGAI +
Sbjct: 55 ITYYEANTSACRLANAMLDMGIKKGDRVVINLPNMPEFLIAAHACFKIGAIVVPTNPRYT 114
Query: 554 AREL 565
REL
Sbjct: 115 KREL 118
>UniRef50_A0QZD4 Cluster: Acetyl-coenzyme A synthetase; n=3;
Corynebacterineae|Rep: Acetyl-coenzyme A synthetase -
Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
Length = 543
Score = 44.8 bits (101), Expect = 0.002
Identities = 22/68 (32%), Positives = 37/68 (54%)
Frame = +2
Query: 374 ISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFA 553
++Y +L++Q ++ A L+ LG+ G V M E ++A+L R GAIH +F FA
Sbjct: 50 LTYGQLREQSTKFAAALSELGIGPGDHVATLMGKSAELVVALLGIWRRGAIHVPLFTAFA 109
Query: 554 ARELXTRI 577
+ R+
Sbjct: 110 PPAITHRL 117
>UniRef50_Q9HEI8 Cluster: Related to acetoacetyl-CoA synthetase;
n=14; Pezizomycotina|Rep: Related to acetoacetyl-CoA
synthetase - Neurospora crassa
Length = 781
Score = 44.8 bits (101), Expect = 0.002
Identities = 39/151 (25%), Positives = 66/151 (43%), Gaps = 16/151 (10%)
Frame = +2
Query: 128 YEKAQQRSLNDPEGFWGEVGSELEWTKP--WDRVLDDSNAPFTK---WWVGGEMSVCYNA 292
+ + + SL + FW +V E + + RV+D+S AP W+ G ++S N
Sbjct: 112 FSELHEYSLRNRSQFWADVWEEANYIHEGTYSRVVDES-APIDAVPIWFEGVKLSYAENV 170
Query: 293 VD-----------RHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGV 439
+ R V ++ A+ R +Y EL+++ RLA + GV
Sbjct: 171 LYSRPKGSSSSQIRSTVGKEDDKVAVTEVREGASETRDATYGELRERAGRLAAAMKARGV 230
Query: 440 SKGARVLIYMPLVPEAIIAMLATNRIGAIHS 532
KG V+I + ++ LAT+ +GAI S
Sbjct: 231 KKGDIVVIVGSNSIDTLLVWLATSWLGAIFS 261
>UniRef50_UPI0000165EEF Cluster: acyl-CoA synthase; n=1; Deinococcus
radiodurans R1|Rep: acyl-CoA synthase - Deinococcus
radiodurans R1
Length = 593
Score = 44.4 bits (100), Expect = 0.002
Identities = 26/73 (35%), Positives = 39/73 (53%)
Frame = +2
Query: 368 RKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGG 547
R+++Y +L DQV RLAG L GV KG RV +++ P I A ++GA+ +
Sbjct: 63 RELTYGDLYDQVGRLAGHLAAQGVRKGDRVGLWLQNSPAWAIGAFAAWQLGAVVVPLTPM 122
Query: 548 FAARELXTRIEHA 586
REL ++ A
Sbjct: 123 LQPRELAFFLQDA 135
>UniRef50_Q9KLB7 Cluster: Acetyl-CoA synthase; n=21; Vibrio|Rep:
Acetyl-CoA synthase - Vibrio cholerae
Length = 649
Score = 44.4 bits (100), Expect = 0.002
Identities = 25/69 (36%), Positives = 36/69 (52%)
Frame = +2
Query: 368 RKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGG 547
+K S+ +L D VS + L GV +G V Y+P +PE +IAMLA +GAI +
Sbjct: 124 KKFSWQQLCDHVSVVQQWLAQNGVGEGDVVAGYLPHLPETVIAMLAATSLGAIWTSTSPD 183
Query: 548 FAARELXTR 574
F + R
Sbjct: 184 FGVESVIER 192
>UniRef50_Q7W4Q6 Cluster: Putative fatty acid CoA ligase; n=3;
Bordetella|Rep: Putative fatty acid CoA ligase -
Bordetella parapertussis
Length = 543
Score = 44.4 bits (100), Expect = 0.002
Identities = 26/71 (36%), Positives = 38/71 (53%)
Frame = +2
Query: 353 LTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHS 532
L D R +++ L+ V LAG L LGV +G RV +++P + LA R+GA+
Sbjct: 36 LIDRDRPVTHAALRAGVLDLAGGLAALGVCRGERVALWLPNCAHWVTMFLACARLGALTL 95
Query: 533 VVFGGFAAREL 565
V F A+EL
Sbjct: 96 AVNTRFRAQEL 106
>UniRef50_Q3M5Z4 Cluster: AMP-dependent synthetase and ligase; n=5;
Bacteria|Rep: AMP-dependent synthetase and ligase -
Anabaena variabilis (strain ATCC 29413 / PCC 7937)
Length = 662
Score = 44.4 bits (100), Expect = 0.002
Identities = 18/50 (36%), Positives = 32/50 (64%)
Frame = +2
Query: 377 SYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAI 526
+Y +L + +R+A L LG+ +G R+ + +P +PE +I+ L +IGAI
Sbjct: 28 TYKQLNEMANRVANALLGLGIERGDRIALLLPNIPEFVISYLGILKIGAI 77
>UniRef50_Q50E73 Cluster: Peptide synthetase 2; n=1; Streptomyces
filamentosus|Rep: Peptide synthetase 2 - Streptomyces
filamentosus (Streptomyces roseosporus)
Length = 7338
Score = 44.0 bits (99), Expect = 0.003
Identities = 25/82 (30%), Positives = 40/82 (48%)
Frame = +2
Query: 341 HDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIG 520
HD L +++Y EL + +RLA L G + V + +P E ++A+LA + G
Sbjct: 5205 HDVALVSGNIRLTYAELDARANRLAHLLLARGAAPETFVAVALPRTEELLVALLAVQKTG 5264
Query: 521 AIHSVVFGGFAARELXTRIEHA 586
A H + GF A L ++ A
Sbjct: 5265 AGHLPLDPGFPAERLSYMLDDA 5286
Score = 40.3 bits (90), Expect = 0.033
Identities = 21/63 (33%), Positives = 32/63 (50%)
Frame = +2
Query: 341 HDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIG 520
HD+ L T +Y EL D+ +RLA L G V + P E+++A+LA + G
Sbjct: 471 HDTALVFTSTSWTYEELNDRANRLARLLVAAGAGSDDFVALAFPRSAESVVAILAVLKAG 530
Query: 521 AIH 529
A +
Sbjct: 531 AAY 533
Score = 33.9 bits (74), Expect = 2.8
Identities = 17/53 (32%), Positives = 29/53 (54%)
Frame = +2
Query: 371 KISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIH 529
++SY EL + +RLA L G V + +P P+ ++A+LA + GA +
Sbjct: 6270 ELSYRELNTRANRLAHVLAEHGAGPERFVGVALPRSPDLVVALLAVVKSGAAY 6322
Score = 32.7 bits (71), Expect = 6.5
Identities = 26/93 (27%), Positives = 44/93 (47%)
Frame = +2
Query: 308 VNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEA 487
V RG+ A+V++ + +SY EL + +RLAG L G V + +P +
Sbjct: 2601 VAARGDAPAVVYEGEV------LSYRELDARANRLAGLLVGRGAGPEHFVGVALPRGLDL 2654
Query: 488 IIAMLATNRIGAIHSVVFGGFAARELXTRIEHA 586
I+A+LA + GA + + + A L + A
Sbjct: 2655 IVALLAVLKSGAAYVPLDPEYPAERLVHMVTDA 2687
>UniRef50_Q1GUE8 Cluster: AMP-dependent synthetase and ligase; n=1;
Sphingopyxis alaskensis|Rep: AMP-dependent synthetase
and ligase - Sphingopyxis alaskensis (Sphingomonas
alaskensis)
Length = 571
Score = 44.0 bits (99), Expect = 0.003
Identities = 23/70 (32%), Positives = 37/70 (52%)
Frame = +2
Query: 368 RKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGG 547
R+++Y EL ++ RLAG L G+ K +L+ +P + E + A +IGAI S
Sbjct: 55 RRLTYAELAAEIDRLAGALVAAGIGKDDVLLVQLPNIGEFVALYFAAAKIGAIVSPAAVQ 114
Query: 548 FAARELXTRI 577
+ + EL I
Sbjct: 115 YRSHELTGMI 124
>UniRef50_A3Z2Q3 Cluster: Acyl-CoA synthase; n=1; Synechococcus sp.
WH 5701|Rep: Acyl-CoA synthase - Synechococcus sp. WH
5701
Length = 321
Score = 44.0 bits (99), Expect = 0.003
Identities = 22/51 (43%), Positives = 30/51 (58%)
Frame = +2
Query: 374 ISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAI 526
I+Y L ++V LAG L GV KG RVL+YM P+ +I+ A R A+
Sbjct: 48 ITYRRLNEEVETLAGYLQAQGVKKGDRVLLYMQNSPQYVISYYAILRADAV 98
>UniRef50_A0Z4Z7 Cluster: AMP-dependent synthetase and ligase; n=1;
marine gamma proteobacterium HTCC2080|Rep: AMP-dependent
synthetase and ligase - marine gamma proteobacterium
HTCC2080
Length = 572
Score = 44.0 bits (99), Expect = 0.003
Identities = 28/71 (39%), Positives = 38/71 (53%), Gaps = 1/71 (1%)
Frame = +2
Query: 371 KISYNELKDQVSRLAGKLTT-LGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGG 547
++SY E +VSR A L+ GVSKG RV I M PE +I +LA +GA+ +
Sbjct: 65 RLSYGEFARRVSRFAQVLSKDFGVSKGDRVAIAMRNYPEYVITLLAAASLGAVAVHMNAW 124
Query: 548 FAARELXTRIE 580
+ A EL E
Sbjct: 125 WTAHELAYGFE 135
>UniRef50_A0LVM6 Cluster: Acetoacetyl-CoA synthase; n=5;
Bacteria|Rep: Acetoacetyl-CoA synthase - Acidothermus
cellulolyticus (strain ATCC 43068 / 11B)
Length = 687
Score = 44.0 bits (99), Expect = 0.003
Identities = 26/73 (35%), Positives = 40/73 (54%), Gaps = 1/73 (1%)
Frame = +2
Query: 359 DTVRKI-SYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSV 535
D VR+ S+++L+ VSR AG L +G++ G V ++P P+A + LA IGAI +
Sbjct: 147 DGVRETWSWHQLRSTVSRAAGALAAVGITAGDVVAAWLPNCPQAYVVALAAAWIGAIFTS 206
Query: 536 VFGGFAARELXTR 574
F A + R
Sbjct: 207 ASPEFGAPAVLDR 219
>UniRef50_A7SNY7 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 567
Score = 44.0 bits (99), Expect = 0.003
Identities = 25/86 (29%), Positives = 41/86 (47%)
Frame = +2
Query: 269 EMSVCYNAVDRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKG 448
E + +D H ++ + D + + +++ E +DQ LA KLT LG+ +G
Sbjct: 17 EHRTLFQLLDHHASKFPNKEAIIYRDE--NNNRKSLTFQEYRDQSRVLAAKLTELGLRRG 74
Query: 449 ARVLIYMPLVPEAIIAMLATNRIGAI 526
VL +P E I +A RIGA+
Sbjct: 75 HLVLALLPSEMEFAIVQMALGRIGAV 100
>UniRef50_Q2W0K6 Cluster: Acyl-coenzyme A synthetase/AMP-(Fatty)
acid ligase; n=4; Magnetospirillum|Rep: Acyl-coenzyme A
synthetase/AMP-(Fatty) acid ligase - Magnetospirillum
magneticum (strain AMB-1 / ATCC 700264)
Length = 549
Score = 43.6 bits (98), Expect = 0.003
Identities = 24/93 (25%), Positives = 51/93 (54%), Gaps = 1/93 (1%)
Frame = +2
Query: 251 KWWVGGEMSVCYNAVDRHVVNGR-GEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLT 427
+W + ++ ++ DR + G G + AL+ ++ V + +++ L+ +RLA L
Sbjct: 16 RWKIPERYNLAFDVCDRQTMAGADGHRTALIVEAA-DGGVERHTFHMLRLLSNRLANGLA 74
Query: 428 TLGVSKGARVLIYMPLVPEAIIAMLATNRIGAI 526
+G++ G RV + +P EA + +LA ++GA+
Sbjct: 75 AMGIAPGDRVAMALPAGLEAAVTLLAVTKMGAV 107
>UniRef50_Q9LCU0 Cluster: PstD; n=2; Mycobacterium avium|Rep: PstD -
Mycobacterium avium
Length = 1400
Score = 43.6 bits (98), Expect = 0.003
Identities = 23/66 (34%), Positives = 35/66 (53%)
Frame = +2
Query: 368 RKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGG 547
R +Y EL + +RLA L+ G G RV + +P EA++A+LA + GA + + G
Sbjct: 461 RSFTYRELYESTNRLAHLLSDHGAGPGQRVAVVIPRSAEAVVAILAVLKTGAAYVPIDPG 520
Query: 548 FAAREL 565
A L
Sbjct: 521 VPAARL 526
>UniRef50_A6V359 Cluster: Linear gramicidin synthetase subunit C;
n=4; Proteobacteria|Rep: Linear gramicidin synthetase
subunit C - Pseudomonas aeruginosa PA7
Length = 528
Score = 43.6 bits (98), Expect = 0.003
Identities = 21/52 (40%), Positives = 32/52 (61%)
Frame = +2
Query: 368 RKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGA 523
R++SY +L Q +RLA +L GV G + + +P PE I+A+LA + GA
Sbjct: 52 RELSYAQLNAQANRLAWQLLARGVQTGDVIAVVLPRSPELIVALLAILKAGA 103
>UniRef50_Q9C8A3 Cluster: Acetyl-CoA synthetase, putative;
45051-31547; n=12; Magnoliophyta|Rep: Acetyl-CoA
synthetase, putative; 45051-31547 - Arabidopsis thaliana
(Mouse-ear cress)
Length = 2655
Score = 43.6 bits (98), Expect = 0.003
Identities = 39/157 (24%), Positives = 70/157 (44%), Gaps = 6/157 (3%)
Frame = +2
Query: 128 YEKAQQRSLNDPEGFWGEVGSELEW---TKPWDRVLDDSNAPFTKWWVGGEMSV--CYNA 292
+E ++ S+ PE +W V EL T P R + + + P W +++ C
Sbjct: 121 FELFRRFSVEHPEVYWSFVIDELSLVFHTPP--RCILNKSKPEGTWLPDAVLNIAECCLM 178
Query: 293 VDRHVVNGRGEQFALVHDSPLTDT-VRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYM 469
H + + D+ V +++ EL++QV +A ++ KG + I M
Sbjct: 179 PSSHPKKEDDSVAVVWRNEGFDDSPVNRMTIKELREQVMLVANAISG-SFEKGDTIAIDM 237
Query: 470 PLVPEAIIAMLATNRIGAIHSVVFGGFAARELXTRIE 580
P+ +A+I LA G I + FAA+E+ TR++
Sbjct: 238 PMTVDAVIIYLAIILAGCIVVSIADSFAAKEIATRLK 274
>UniRef50_Q6L1D6 Cluster: Long chain fatty acid CoA ligase; n=1;
Picrophilus torridus|Rep: Long chain fatty acid CoA
ligase - Picrophilus torridus
Length = 557
Score = 43.6 bits (98), Expect = 0.003
Identities = 25/68 (36%), Positives = 39/68 (57%)
Frame = +2
Query: 323 EQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAML 502
E+ AL+H T+ +ISY +L ++ + L L G+ KG+ V + MP+VPE A+
Sbjct: 54 EKTALIHYDMDTERSMEISYRDLVNRSNALLSFLRLNGLKKGSIVYLMMPVVPEQWYALT 113
Query: 503 ATNRIGAI 526
AT + G I
Sbjct: 114 ATIKGGMI 121
>UniRef50_Q83MG9 Cluster: Probable crotonobetaine/carnitine-CoA
ligase; n=39; Bacteria|Rep: Probable
crotonobetaine/carnitine-CoA ligase - Shigella flexneri
Length = 517
Score = 43.6 bits (98), Expect = 0.003
Identities = 24/69 (34%), Positives = 37/69 (53%)
Frame = +2
Query: 320 GEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAM 499
G + AL+ +S V + SY EL +++R A TLG+ KG +V +++ PE I
Sbjct: 21 GHKTALICESS-GGVVNRYSYLELNQEINRTANLFYTLGIRKGNKVALHLDNCPEFIFCW 79
Query: 500 LATNRIGAI 526
+IGAI
Sbjct: 80 FGLAKIGAI 88
>UniRef50_Q3KF66 Cluster: Amino acid adenylation; n=2;
Pseudomonas|Rep: Amino acid adenylation - Pseudomonas
fluorescens (strain PfO-1)
Length = 1070
Score = 43.2 bits (97), Expect = 0.005
Identities = 22/59 (37%), Positives = 35/59 (59%)
Frame = +2
Query: 353 LTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIH 529
LTD +++Y +L+ QV RLA L GV + + V + +P ++AMLA R+GA +
Sbjct: 477 LTDETGRLNYAQLQAQVERLAAGLHAEGVGRDSIVALALPRSAALVVAMLAIWRVGAAY 535
>UniRef50_Q140M1 Cluster: Putative long chain fatty acid CoA ligase;
n=1; Burkholderia xenovorans LB400|Rep: Putative long
chain fatty acid CoA ligase - Burkholderia xenovorans
(strain LB400)
Length = 543
Score = 43.2 bits (97), Expect = 0.005
Identities = 24/70 (34%), Positives = 35/70 (50%)
Frame = +2
Query: 374 ISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFA 553
ISY ++K+ V R+A L G+ +G V ++MP +P LA +IGAI G
Sbjct: 42 ISYQQMKEHVDRVARALLASGIERGDVVAVWMPNLPHFAFIELACAKIGAI----IGAIN 97
Query: 554 ARELXTRIEH 583
R +EH
Sbjct: 98 TRSKVFEVEH 107
>UniRef50_Q124C5 Cluster: AMP-dependent synthetase and ligase; n=4;
Burkholderiales|Rep: AMP-dependent synthetase and ligase
- Polaromonas sp. (strain JS666 / ATCC BAA-500)
Length = 561
Score = 43.2 bits (97), Expect = 0.005
Identities = 26/71 (36%), Positives = 38/71 (53%)
Frame = +2
Query: 368 RKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGG 547
R +SY +L D S L L +LG+ GARV I +P +P+ + M A R G V
Sbjct: 47 RWMSYAQLDDLSSALGAWLQSLGLEPGARVAIMLPNIPQFAVTMAAVLRAGYTCVNVNPL 106
Query: 548 FAARELXTRIE 580
+ AREL +++
Sbjct: 107 YTARELEHQLK 117
>UniRef50_A7DD68 Cluster: AMP-dependent synthetase and ligase; n=3;
Alphaproteobacteria|Rep: AMP-dependent synthetase and
ligase - Methylobacterium extorquens PA1
Length = 551
Score = 43.2 bits (97), Expect = 0.005
Identities = 27/65 (41%), Positives = 36/65 (55%)
Frame = +2
Query: 359 DTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVV 538
D R ++Y D + R+AG L GV KG RV I+ + I+AML RIGAI ++V
Sbjct: 56 DRDRGLTYAGAVDAMERMAGALHDAGVGKGDRVTIFAHNGLDYIVAMLGAWRIGAIAALV 115
Query: 539 FGGFA 553
FA
Sbjct: 116 NVKFA 120
>UniRef50_A5A9U3 Cluster: Mps2 protein; n=2; Mycobacterium|Rep: Mps2
protein - Mycobacterium abscessus
Length = 2581
Score = 43.2 bits (97), Expect = 0.005
Identities = 24/57 (42%), Positives = 32/57 (56%)
Frame = +2
Query: 353 LTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGA 523
LT R +Y EL + +RLA L+ G + G V + MP EAIIA+LA + GA
Sbjct: 1570 LTFEGRSTTYGELDEAANRLANLLSVYGAAPGESVALLMPRSDEAIIAILAILKTGA 1626
>UniRef50_A4BLS1 Cluster: Putative non-ribosomal peptide synthase;
n=1; Nitrococcus mobilis Nb-231|Rep: Putative
non-ribosomal peptide synthase - Nitrococcus mobilis
Nb-231
Length = 2190
Score = 43.2 bits (97), Expect = 0.005
Identities = 22/52 (42%), Positives = 30/52 (57%)
Frame = +2
Query: 374 ISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIH 529
+SY EL+ Q +AG L GV G V + +P PE IIA+L T GA++
Sbjct: 582 LSYGELRRQAMAVAGYLVAKGVRPGDVVAVLLPKGPEQIIAVLGTLAAGAVY 633
Score = 35.5 bits (78), Expect = 0.93
Identities = 19/51 (37%), Positives = 27/51 (52%)
Frame = +2
Query: 377 SYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIH 529
SY EL D R+A +L GVS V +++P P+ I A+L GA +
Sbjct: 1622 SYGELADSALRVAAELIRGGVSPEEVVAVHLPKSPDQIAAVLGVLAAGAAY 1672
>UniRef50_A0K0Y8 Cluster: AMP-dependent synthetase and ligase; n=8;
Bacteria|Rep: AMP-dependent synthetase and ligase -
Arthrobacter sp. (strain FB24)
Length = 583
Score = 43.2 bits (97), Expect = 0.005
Identities = 22/52 (42%), Positives = 30/52 (57%)
Frame = +2
Query: 371 KISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAI 526
+ SY EL +S+ A L LGV G RV + MP P+ I+A A R+GA+
Sbjct: 61 RTSYRELGALISKAAAGLKKLGVKAGDRVALVMPNCPQHIVAFHAVLRLGAV 112
>UniRef50_Q7CT27 Cluster: AGR_L_2309p; n=2; Agrobacterium tumefaciens
str. C58|Rep: AGR_L_2309p - Agrobacterium tumefaciens
(strain C58 / ATCC 33970)
Length = 2566
Score = 42.7 bits (96), Expect = 0.006
Identities = 23/59 (38%), Positives = 33/59 (55%)
Frame = +2
Query: 353 LTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIH 529
+TD R +SY EL + RLA L G+ +G RV I + E ++A+LA R GA +
Sbjct: 1555 VTDQDRSLSYAELDWRADRLASGLVAAGIGRGKRVGIRLERSVELVVAILAVLRTGAAY 1613
>UniRef50_A6VYF7 Cluster: Amino acid adenylation domain; n=1;
Marinomonas sp. MWYL1|Rep: Amino acid adenylation domain
- Marinomonas sp. MWYL1
Length = 2971
Score = 42.7 bits (96), Expect = 0.006
Identities = 22/51 (43%), Positives = 32/51 (62%)
Frame = +2
Query: 371 KISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGA 523
KISY+EL ++ +RLA L + GV K RV +Y+ E I+ +LA + GA
Sbjct: 554 KISYSELNERANRLAHFLISKGVEKQDRVAVYLDKSVEMIVTLLAILKAGA 604
>UniRef50_A3P7D6 Cluster: Non-ribosomal peptide synthase; n=34;
Bacteria|Rep: Non-ribosomal peptide synthase -
Burkholderia pseudomallei (strain 1106a)
Length = 4468
Score = 42.7 bits (96), Expect = 0.006
Identities = 25/66 (37%), Positives = 34/66 (51%)
Frame = +2
Query: 368 RKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGG 547
R ++Y EL +RLA L GV G RV +Y PE +I MLAT + G + + G
Sbjct: 570 RALTYAELNRCANRLAHYLRARGVRGGDRVALYARRSPELLIGMLATLKAGGAYVPLDPG 629
Query: 548 FAAREL 565
+ A L
Sbjct: 630 YPAERL 635
>UniRef50_Q4PHX8 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 828
Score = 42.7 bits (96), Expect = 0.006
Identities = 22/65 (33%), Positives = 36/65 (55%)
Frame = +2
Query: 344 DSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGA 523
DS + K+++ EL+ +V+ LA +GV KG R+ I+A LA N +GA
Sbjct: 142 DSDVNAQAVKVTWGELRRRVALLAETFRRIGVKKGDRLAHVSANTSSPIVATLAANSVGA 201
Query: 524 IHSVV 538
I+S++
Sbjct: 202 IYSLI 206
>UniRef50_UPI0000E45C70 Cluster: PREDICTED: hypothetical protein;
n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 556
Score = 42.3 bits (95), Expect = 0.008
Identities = 22/57 (38%), Positives = 36/57 (63%)
Frame = +2
Query: 356 TDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAI 526
++T ++ ++ ++K++V LA L +LGV +G RV I+ P I+ AT RIGAI
Sbjct: 71 SETGQRRTFQQIKEKVDSLAAGLLSLGVQRGDRVGIWSPNTLGWILTQYATARIGAI 127
>UniRef50_Q6MIK4 Cluster: AMP-ligase; n=1; Bdellovibrio
bacteriovorus|Rep: AMP-ligase - Bdellovibrio
bacteriovorus
Length = 805
Score = 42.3 bits (95), Expect = 0.008
Identities = 19/52 (36%), Positives = 31/52 (59%)
Frame = +2
Query: 371 KISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAI 526
+I+Y +++ A L +G+ KG RV+I++P+ + AM A RIGAI
Sbjct: 291 EITYRHFAARINSFARGLMDIGIKKGDRVIIFLPMSLDMYTAMFAVQRIGAI 342
>UniRef50_Q3M1P5 Cluster: Amino acid adenylation; n=2;
Cyanobacteria|Rep: Amino acid adenylation - Anabaena
variabilis (strain ATCC 29413 / PCC 7937)
Length = 2791
Score = 42.3 bits (95), Expect = 0.008
Identities = 23/54 (42%), Positives = 29/54 (53%)
Frame = +2
Query: 365 VRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAI 526
V+ ++Y EL +Q R+AG L GV KG RVL+ P E I A GAI
Sbjct: 42 VQSLTYGELDNQAQRIAGLLQAFGVKKGERVLLLYPPGLEFITAFFGCLYAGAI 95
Score = 37.1 bits (82), Expect = 0.30
Identities = 19/72 (26%), Positives = 37/72 (51%)
Frame = +2
Query: 371 KISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGF 550
+I+Y +L Q ++LA L LGV K V +Y+ P+ ++++LA + G + + +
Sbjct: 1175 EITYKQLNQQANQLAHYLQGLGVKKEVLVGVYLERSPQMVVSILAILKAGGAYLPLDPSY 1234
Query: 551 AARELXTRIEHA 586
L ++ A
Sbjct: 1235 PRERLAFMLQDA 1246
>UniRef50_Q3WHP4 Cluster: AMP-dependent synthetase and ligase; n=1;
Frankia sp. EAN1pec|Rep: AMP-dependent synthetase and
ligase - Frankia sp. EAN1pec
Length = 541
Score = 42.3 bits (95), Expect = 0.008
Identities = 21/56 (37%), Positives = 33/56 (58%)
Frame = +2
Query: 359 DTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAI 526
D ++SY +L D+V RLA L LG+ +G RV++++P E I + A +G I
Sbjct: 52 DRDTRLSYRQLTDEVLRLAAGLQDLGLGRGDRVVVHLPNTYEYIAFVFALWELGVI 107
>UniRef50_Q06YZ2 Cluster: Nonribosomal peptide synthetase; n=1;
Streptomyces fungicidicus|Rep: Nonribosomal peptide
synthetase - Streptomyces fungicidicus
Length = 6943
Score = 42.3 bits (95), Expect = 0.008
Identities = 24/72 (33%), Positives = 39/72 (54%)
Frame = +2
Query: 371 KISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGF 550
++SY E++++ +RLA KL GV + V + + PE +IA LA + G + V G
Sbjct: 2642 QLSYGEVEERANRLARKLIARGVGPESVVALVLERSPEVVIAALAVLKAGGAYLPVDPGQ 2701
Query: 551 AARELXTRIEHA 586
A + + IE A
Sbjct: 2702 PAERIRSVIEDA 2713
Score = 39.5 bits (88), Expect = 0.057
Identities = 22/72 (30%), Positives = 39/72 (54%)
Frame = +2
Query: 371 KISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGF 550
++SY E++++ +RLA KL V + V + + PE +IA+LA + G + + G
Sbjct: 6383 ELSYREVEERANRLARKLIARDVGPESVVALVLERSPELVIAVLAVLKAGGAYLPIDPGQ 6442
Query: 551 AARELXTRIEHA 586
A + + IE A
Sbjct: 6443 PAERIRSVIEDA 6454
>UniRef50_A3RXA3 Cluster: AMP-(Fatty)acid ligases; n=6;
Burkholderiales|Rep: AMP-(Fatty)acid ligases - Ralstonia
solanacearum UW551
Length = 563
Score = 42.3 bits (95), Expect = 0.008
Identities = 21/53 (39%), Positives = 33/53 (62%)
Frame = +2
Query: 368 RKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAI 526
R I + EL +RLA + LGV++G RV +++ P+ I+A LA ++GAI
Sbjct: 40 RTICWRELDQLSTRLAVQFQRLGVARGDRVALFLQNCPQGILAHLAAAKLGAI 92
>UniRef50_Q0D0Z7 Cluster: Putative uncharacterized protein; n=2;
Pezizomycotina|Rep: Putative uncharacterized protein -
Aspergillus terreus (strain NIH 2624)
Length = 652
Score = 42.3 bits (95), Expect = 0.008
Identities = 34/136 (25%), Positives = 63/136 (46%), Gaps = 4/136 (2%)
Frame = +2
Query: 128 YEKAQQRSLNDPEGFWGEVGS--ELEWTKPWDRVLDDSNAPFTK--WWVGGEMSVCYNAV 295
Y Q S+++P FW V + ++ +D+VL + F + ++ G ++ N +
Sbjct: 57 YNDLWQWSVSEPANFWEHVWNYTPVKTHSQYDQVLGSDSLLFPRPSFFEGSRLNFAENLL 116
Query: 296 DRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPL 475
+ + E + + D +S+ EL+++V R A L G+ G RV ++
Sbjct: 117 --YPASSPEESDIAIIAATEADR-EYVSWGELRERVRRCANSLKGAGLQAGDRVAGFLGN 173
Query: 476 VPEAIIAMLATNRIGA 523
++AMLAT IGA
Sbjct: 174 HTNTVVAMLATTSIGA 189
>UniRef50_Q6KZU2 Cluster: Acetoacetyl-CoA synthetase; n=1;
Picrophilus torridus|Rep: Acetoacetyl-CoA synthetase -
Picrophilus torridus
Length = 624
Score = 42.3 bits (95), Expect = 0.008
Identities = 42/155 (27%), Positives = 68/155 (43%), Gaps = 2/155 (1%)
Frame = +2
Query: 128 YEKAQQRSLNDPEGFWGEVGS--ELEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVDR 301
Y A + S+ D GFW + S +E + R N + W+ E + Y +
Sbjct: 23 YHDAFKNSIKDLNGFWKSLASFYGIELNGSYKR---GENFIDSSWF--NETRINYTDLVL 77
Query: 302 HVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVP 481
N G +++ L + ++IS+NEL V LAG L +G+ KG V Y+
Sbjct: 78 KNKNLNGYSIIYINEK-LNE--KRISWNELSVMVYNLAGFLIEIGLKKGDVVAGYINNNY 134
Query: 482 EAIIAMLATNRIGAIHSVVFGGFAARELXTRIEHA 586
AII+ LA + IG + V F + +R + +
Sbjct: 135 YAIISFLAASLIGCTWTCVSQDFGLGAVISRFQQS 169
>UniRef50_Q5P0J2 Cluster: 4-hydroxybenzoate CoA ligase; n=1;
Azoarcus sp. EbN1|Rep: 4-hydroxybenzoate CoA ligase -
Azoarcus sp. (strain EbN1) (Aromatoleum aromaticum
(strain EbN1))
Length = 493
Score = 41.9 bits (94), Expect = 0.011
Identities = 20/52 (38%), Positives = 31/52 (59%)
Frame = +2
Query: 371 KISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAI 526
K+SY L+D+VSR AG TLG+ G RV+++ P + ++A L G +
Sbjct: 24 KVSYAVLRDRVSRAAGAWKTLGLQPGNRVIVFAPDSVDWVVAYLGAIWAGGV 75
>UniRef50_P71716 Cluster: BIFUNCTIONAL ENZYME MBTA: SALICYL-AMP
LIGASE (SAL-AMP LIGASE) + SALICYL-S-ArCP SYNTHETASE;
n=16; Mycobacterium|Rep: BIFUNCTIONAL ENZYME MBTA:
SALICYL-AMP LIGASE (SAL-AMP LIGASE) + SALICYL-S-ArCP
SYNTHETASE - Mycobacterium tuberculosis
Length = 565
Score = 41.9 bits (94), Expect = 0.011
Identities = 24/64 (37%), Positives = 34/64 (53%)
Frame = +2
Query: 374 ISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFA 553
+SY EL + R A L LG++ G RVL+ +P + +A+ A R GAI + G
Sbjct: 71 LSYAELDQRADRAAAALHGLGITPGDRVLLQLPNGCQFAVALFALLRAGAIPVMCLPGHR 130
Query: 554 AREL 565
A EL
Sbjct: 131 AAEL 134
>UniRef50_Q1V1I6 Cluster: Acetoacetyl-CoA synthase; n=2;
Bacteria|Rep: Acetoacetyl-CoA synthase - Candidatus
Pelagibacter ubique HTCC1002
Length = 653
Score = 41.9 bits (94), Expect = 0.011
Identities = 31/152 (20%), Positives = 70/152 (46%), Gaps = 2/152 (1%)
Frame = +2
Query: 125 EYEKAQQRSLNDPEGFWGEVG--SELEWTKPWDRVLDDSNAPFTKWWVGGEMSVCYNAVD 298
+YE + S+ +P FW + SE++ K ++ K+ + +++ N +
Sbjct: 36 KYESILKWSIENPGNFWSSIWDFSEIKGFKSKIKIKKSKIFYKNKFLLNSKLNFAENLLS 95
Query: 299 RHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLV 478
+ N + + + ++ + + S+ EL VS+++ L ++ + + R+ YMP
Sbjct: 96 K---NNKDKAITFISENSFRE---ERSWQELNLNVSKISKFLKSINIKEKDRLAAYMPNT 149
Query: 479 PEAIIAMLATNRIGAIHSVVFGGFAARELXTR 574
E + A +A++ +GAI S F + + R
Sbjct: 150 IETVEAFIASSSLGAIWSSCSPDFGVKGVVER 181
>UniRef50_Q0LP24 Cluster: Amino acid adenylation; n=1; Herpetosiphon
aurantiacus ATCC 23779|Rep: Amino acid adenylation -
Herpetosiphon aurantiacus ATCC 23779
Length = 2419
Score = 41.9 bits (94), Expect = 0.011
Identities = 23/52 (44%), Positives = 32/52 (61%)
Frame = +2
Query: 368 RKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGA 523
+++SY EL + S+LAG L +LGV A V I M PE ++AML + GA
Sbjct: 1841 QQLSYAELDQRSSQLAGYLQSLGVQAFATVGICMQRSPELVVAMLGVLKAGA 1892
>UniRef50_A6UHL1 Cluster: AMP-dependent synthetase and ligase; n=2;
Sinorhizobium|Rep: AMP-dependent synthetase and ligase -
Sinorhizobium medicae WSM419
Length = 515
Score = 41.9 bits (94), Expect = 0.011
Identities = 25/66 (37%), Positives = 35/66 (53%)
Frame = +2
Query: 368 RKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGG 547
R++SY EL D +RLA L GV + RVL +M EA +A+ A + GA S +
Sbjct: 25 RRLSYAELDDLSTRLAAALAANGVKRNDRVLAFMDNCWEAAVAIFAILKAGATFSPINAS 84
Query: 548 FAAREL 565
A +L
Sbjct: 85 TKADKL 90
>UniRef50_A6P624 Cluster: Nonribosomal peptide synthetase; n=1;
Microcystis aeruginosa|Rep: Nonribosomal peptide
synthetase - Microcystis aeruginosa
Length = 1415
Score = 41.9 bits (94), Expect = 0.011
Identities = 19/52 (36%), Positives = 32/52 (61%)
Frame = +2
Query: 374 ISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIH 529
ISY EL Q ++LA L+ LG+ G RV +Y+ P I+++L+ + G ++
Sbjct: 565 ISYQELNRQANQLAHYLSNLGIKSGERVGVYLERSPLVIVSILSIFKAGGVY 616
>UniRef50_A3VQJ0 Cluster: Acyl-CoA synthase; n=1; Parvularcula
bermudensis HTCC2503|Rep: Acyl-CoA synthase -
Parvularcula bermudensis HTCC2503
Length = 586
Score = 41.9 bits (94), Expect = 0.011
Identities = 22/68 (32%), Positives = 35/68 (51%)
Frame = +2
Query: 377 SYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFAA 556
+Y L + A L + G++ G RV I MP VP+ ++ +L R G + V + A
Sbjct: 75 TYRRLDEDSRAFASYLRSKGINPGDRVAIMMPTVPQYVVCLLGALRAGCVMVGVNPLYTA 134
Query: 557 RELXTRIE 580
REL ++E
Sbjct: 135 RELCHQLE 142
>UniRef50_Q2UH98 Cluster: Acyl-CoA synthetases; n=4;
Eurotiomycetidae|Rep: Acyl-CoA synthetases - Aspergillus
oryzae
Length = 606
Score = 41.9 bits (94), Expect = 0.011
Identities = 30/88 (34%), Positives = 42/88 (47%)
Frame = +2
Query: 320 GEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAM 499
GE LV P T T + +Y+ L D+ RLA L +G+ KG R+ I + I
Sbjct: 51 GEHECLVF--PWTGT--RWTYSALNDEADRLAQGLLAIGIHKGDRIGIMAGNCEQYISVF 106
Query: 500 LATNRIGAIHSVVFGGFAARELXTRIEH 583
A R+GAI V+ + EL +EH
Sbjct: 107 FAAARVGAILVVLNNTYTPSELYYALEH 134
>UniRef50_Q7N5R3 Cluster: Complete genome; segment 7/17; n=1;
Photorhabdus luminescens subsp. laumondii|Rep: Complete
genome; segment 7/17 - Photorhabdus luminescens subsp.
laumondii
Length = 4160
Score = 41.5 bits (93), Expect = 0.014
Identities = 22/51 (43%), Positives = 31/51 (60%)
Frame = +2
Query: 374 ISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAI 526
+SY +L + +A +L +GV +G RV I M P + AMLA NRIGA+
Sbjct: 1567 LSYQQLDTLTAYVAQQLQQVGVGRGDRVGILMGHHPHNVTAMLAINRIGAV 1617
Score = 35.1 bits (77), Expect = 1.2
Identities = 16/54 (29%), Positives = 28/54 (51%)
Frame = +2
Query: 368 RKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIH 529
++ +Y +L + L K+ GV G+RV + M PE +I+ A GA++
Sbjct: 481 QRFTYAQLDEYAQYLLAKMRQCGVGPGSRVAVLMSYRPEIVISFYAILSAGAVY 534
>UniRef50_Q9L8H4 Cluster: Actinomycin synthetase III; n=1;
Streptomyces anulatus|Rep: Actinomycin synthetase III -
Streptomyces chrysomallus
Length = 4247
Score = 41.5 bits (93), Expect = 0.014
Identities = 22/70 (31%), Positives = 37/70 (52%), Gaps = 1/70 (1%)
Frame = +2
Query: 323 EQFALVHDSP-LTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAM 499
+Q L D+P L +SY+EL + + LA +LTT G+ G V + + P+ + +
Sbjct: 3004 QQVTLTPDAPALVSDGATLSYSELNTRANHLAHQLTTRGIRPGDAVAVLLQRSPDTVTTV 3063
Query: 500 LATNRIGAIH 529
LA + GA +
Sbjct: 3064 LALAKTGATY 3073
Score = 32.3 bits (70), Expect = 8.6
Identities = 19/71 (26%), Positives = 34/71 (47%)
Frame = +2
Query: 374 ISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFA 553
+ Y EL ++ +RLA L GV V + +P + ++A+LA + GA + + +
Sbjct: 484 LRYRELDERANRLAHLLAAHGVGPERIVALALPRSVDLVVAVLAVLKAGAAYLPLDPEYP 543
Query: 554 ARELXTRIEHA 586
A L + A
Sbjct: 544 ANRLAHMVTDA 554
>UniRef50_Q5DIU0 Cluster: PvdI; n=3; cellular organisms|Rep: PvdI -
Pseudomonas aeruginosa
Length = 3680
Score = 41.5 bits (93), Expect = 0.014
Identities = 24/71 (33%), Positives = 36/71 (50%)
Frame = +2
Query: 368 RKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGG 547
+++SY EL Q +RLA +L LGV RV I M E ++A LA + G + +
Sbjct: 3094 QRLSYGELDSQANRLAQRLVELGVGPEVRVAIAMRRSAEIMVAFLAVLKAGGAYVPLDIA 3153
Query: 548 FAARELXTRIE 580
+ A L +E
Sbjct: 3154 YPAERLRYMLE 3164
>UniRef50_Q3WFP5 Cluster: AMP-dependent synthetase and ligase; n=1;
Frankia sp. EAN1pec|Rep: AMP-dependent synthetase and
ligase - Frankia sp. EAN1pec
Length = 522
Score = 41.5 bits (93), Expect = 0.014
Identities = 24/62 (38%), Positives = 32/62 (51%)
Frame = +2
Query: 377 SYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFAA 556
SY EL +Q R AG L +LGV G RV +P + + A RIGA+ + + AA
Sbjct: 55 SYAELDEQADRAAGALWSLGVRPGDRVAACLPNDLDIVAAFHGAQRIGAVWAGIGEALAA 114
Query: 557 RE 562
E
Sbjct: 115 SE 116
>UniRef50_Q3WCA8 Cluster: AMP-dependent synthetase and ligase; n=1;
Frankia sp. EAN1pec|Rep: AMP-dependent synthetase and
ligase - Frankia sp. EAN1pec
Length = 557
Score = 41.5 bits (93), Expect = 0.014
Identities = 17/54 (31%), Positives = 36/54 (66%)
Frame = +2
Query: 365 VRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAI 526
V++++Y L ++V L+ L ++GV +G RV++++ PE +++ A R+GA+
Sbjct: 47 VQRLTYATLVERVRALSAGLASIGVRRGDRVVLWLTNTPEWVVSHFACMRLGAV 100
>UniRef50_Q3L908 Cluster: Putative fatty-acid--CoA ligase; n=1;
Rhodococcus erythropolis PR4|Rep: Putative
fatty-acid--CoA ligase - Rhodococcus erythropolis
(strain PR4)
Length = 511
Score = 41.5 bits (93), Expect = 0.014
Identities = 23/68 (33%), Positives = 36/68 (52%)
Frame = +2
Query: 377 SYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFAA 556
SY +L ++++ A L +LGV KG RV + P ++A+ ++GAI S A
Sbjct: 29 SYGQLDREINQYANALLSLGVQKGDRVAVLSPNSDRFLLALYGAFKVGAIVSPFNPRSTA 88
Query: 557 RELXTRIE 580
REL +E
Sbjct: 89 RELAYLLE 96
>UniRef50_O68487 Cluster: Actinomycin synthetase II; n=1; Streptomyces
anulatus|Rep: Actinomycin synthetase II - Streptomyces
chrysomallus
Length = 2611
Score = 41.5 bits (93), Expect = 0.014
Identities = 22/70 (31%), Positives = 37/70 (52%), Gaps = 1/70 (1%)
Frame = +2
Query: 323 EQFALVHDSP-LTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAM 499
+Q L D+P L +SY+EL + + LA +LTT G+ G V + + P+ + +
Sbjct: 1540 QQVTLTPDAPALVSDGATLSYSELNTRANHLAHQLTTRGIRPGDAVAVLLQRSPDTVTTV 1599
Query: 500 LATNRIGAIH 529
LA + GA +
Sbjct: 1600 LALAKTGATY 1609
Score = 33.1 bits (72), Expect = 4.9
Identities = 19/71 (26%), Positives = 35/71 (49%)
Frame = +2
Query: 374 ISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFA 553
++Y EL ++ +RLA L GV V + +P + ++A+LA + GA + + +
Sbjct: 489 LTYRELDERANRLAHLLAAHGVGPERIVALALPRSVDLVVAVLAVLKAGAAYLPLDPEYP 548
Query: 554 ARELXTRIEHA 586
A L + A
Sbjct: 549 ANRLAHMVTDA 559
>UniRef50_A6GK66 Cluster: Non-ribosomal peptide synthetase; n=1;
Plesiocystis pacifica SIR-1|Rep: Non-ribosomal peptide
synthetase - Plesiocystis pacifica SIR-1
Length = 3382
Score = 41.5 bits (93), Expect = 0.014
Identities = 21/54 (38%), Positives = 33/54 (61%)
Frame = +2
Query: 368 RKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIH 529
R++SY +L+ +V LA +L LGV++G RV + E ++A LA N GA +
Sbjct: 1475 RRLSYAQLRGRVVELAHRLVALGVARGDRVAVVARKGWEQVVAALAVNVAGAAY 1528
>UniRef50_A4X9C6 Cluster: Thioester reductase domain; n=2;
Salinispora|Rep: Thioester reductase domain -
Salinispora tropica CNB-440
Length = 2376
Score = 41.5 bits (93), Expect = 0.014
Identities = 23/56 (41%), Positives = 31/56 (55%)
Frame = +2
Query: 359 DTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAI 526
D R +SY +L + +RLAG L LG+ G R +I M EA+ + LA R G I
Sbjct: 28 DGKRGVSYADLDRRTARLAGHLAALGLETGGRAVILMGNSVEAVESSLAVIRAGGI 83
>UniRef50_A4FFC7 Cluster: Putative fatty-acid--CoA ligase; n=1;
Saccharopolyspora erythraea NRRL 2338|Rep: Putative
fatty-acid--CoA ligase - Saccharopolyspora erythraea
(strain NRRL 23338)
Length = 568
Score = 41.5 bits (93), Expect = 0.014
Identities = 22/66 (33%), Positives = 37/66 (56%)
Frame = +2
Query: 389 LKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFAARELX 568
L+++V+ LA L LG+ +G R+LI M PE +A LA +GA+ + ++ +L
Sbjct: 10 LREEVAALARGLAGLGLRRGDRMLISMSHRPEHWVADLAAAHVGAVSCTTYDTLSSEQLR 69
Query: 569 TRIEHA 586
EH+
Sbjct: 70 FLAEHS 75
>UniRef50_A7RFX5 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 704
Score = 41.5 bits (93), Expect = 0.014
Identities = 19/52 (36%), Positives = 33/52 (63%)
Frame = +2
Query: 371 KISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAI 526
+ ++ EL+++ +LA L +LG+ +G RV I+ P + E +I+ T RIG I
Sbjct: 97 RATFAELREEADQLAASLLSLGIKRGDRVGIWGPNMREWVISQFGTARIGVI 148
>UniRef50_Q82GQ6 Cluster: Putative cyclohex-1-ene-1-carboxylate:CoA
ligase; n=3; Actinomycetales|Rep: Putative
cyclohex-1-ene-1-carboxylate:CoA ligase - Streptomyces
avermitilis
Length = 499
Score = 41.1 bits (92), Expect = 0.019
Identities = 22/66 (33%), Positives = 34/66 (51%)
Frame = +2
Query: 368 RKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGG 547
R +S+ EL+D+ R+A L +GV G V +P E + A R+GA+ S V
Sbjct: 36 RSLSFGELRDRAERVAAGLYDMGVRPGTVVAWQLPTRIETALLSFALARLGAVQSPVIPF 95
Query: 548 FAAREL 565
+ RE+
Sbjct: 96 YRDREV 101
>UniRef50_Q4JSW1 Cluster: Acyl-CoA synthetase; n=1; Corynebacterium
jeikeium K411|Rep: Acyl-CoA synthetase - Corynebacterium
jeikeium (strain K411)
Length = 577
Score = 41.1 bits (92), Expect = 0.019
Identities = 21/64 (32%), Positives = 36/64 (56%)
Frame = +2
Query: 374 ISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFA 553
++Y + QV +A L LGV G RV + +P P+ +I + A +++GA+ + +
Sbjct: 60 MTYGDFLKQVKSVAAGLRELGVRPGDRVAVTLPNCPQHLITIFAAHKLGAVVAEHNPLYT 119
Query: 554 AREL 565
AREL
Sbjct: 120 AREL 123
>UniRef50_Q8RNW9 Cluster: Adenylate-forming enzyme; n=2;
Streptomyces|Rep: Adenylate-forming enzyme -
Streptomyces ansochromogenes
Length = 561
Score = 41.1 bits (92), Expect = 0.019
Identities = 25/71 (35%), Positives = 41/71 (57%), Gaps = 4/71 (5%)
Frame = +2
Query: 338 VHDSPLTDTVR----KISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLA 505
V + P + VR +++ EL D V+ A +L LG+++G RVL+ +P E ++ LA
Sbjct: 41 VAEDPEKEAVRGPGGRLTRRELADAVAGAAARLAGLGITRGDRVLVQLPNDLELVVLPLA 100
Query: 506 TNRIGAIHSVV 538
R+GA H V+
Sbjct: 101 LMRLGA-HPVM 110
>UniRef50_Q28MM6 Cluster: AMP-dependent synthetase and ligase; n=10;
Alphaproteobacteria|Rep: AMP-dependent synthetase and
ligase - Jannaschia sp. (strain CCS1)
Length = 485
Score = 41.1 bits (92), Expect = 0.019
Identities = 25/65 (38%), Positives = 35/65 (53%)
Frame = +2
Query: 332 ALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATN 511
A+ D P DT +SY +L+ ++ AG L GV+ G RVL + PEA+I LAT
Sbjct: 17 AIFLDVPGGDT---LSYGDLRHAIATAAGALHAAGVAPGDRVLCQIAKSPEALIIYLATV 73
Query: 512 RIGAI 526
G +
Sbjct: 74 AAGGV 78
>UniRef50_Q1PUQ3 Cluster: Similar to long chain acyl-coenzyme A
synthetase; n=1; Candidatus Kuenenia
stuttgartiensis|Rep: Similar to long chain acyl-coenzyme
A synthetase - Candidatus Kuenenia stuttgartiensis
Length = 528
Score = 41.1 bits (92), Expect = 0.019
Identities = 17/53 (32%), Positives = 32/53 (60%)
Frame = +2
Query: 368 RKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAI 526
+KI+Y+ + LA +L +GV +G R+ + +P +PE +I+ + + GAI
Sbjct: 56 KKINYHGYNTLANSLANELLNIGVKRGDRIGLMLPRIPELVISFMGIAKAGAI 108
>UniRef50_Q12IB7 Cluster: Amino acid adenylation; n=1; Shewanella
denitrificans OS217|Rep: Amino acid adenylation -
Shewanella denitrificans (strain OS217 / ATCC BAA-1090 /
DSM 15013)
Length = 2457
Score = 41.1 bits (92), Expect = 0.019
Identities = 22/54 (40%), Positives = 32/54 (59%)
Frame = +2
Query: 368 RKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIH 529
+KISY L Q ++LA + TLGV G + +MP P I + LA ++GAI+
Sbjct: 1118 QKISYESLNRQANQLARYMQTLGVKPGDVIGCHMPRSPLMITSALAILKLGAIY 1171
>UniRef50_Q0SBN7 Cluster: Probable acid-CoA ligase; n=1; Rhodococcus
sp. RHA1|Rep: Probable acid-CoA ligase - Rhodococcus sp.
(strain RHA1)
Length = 538
Score = 41.1 bits (92), Expect = 0.019
Identities = 24/71 (33%), Positives = 37/71 (52%)
Frame = +2
Query: 353 LTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHS 532
+ D R++SY EL + RLAG L G+ G V+ +P EAI+ RIGA+ +
Sbjct: 43 VVDGDRQVSYAELDAMIRRLAGVLLERGIRPGDSVVWQLPNWLEAIVVHHGALRIGAVST 102
Query: 533 VVFGGFAAREL 565
+ + RE+
Sbjct: 103 PIIPIYRHREV 113
>UniRef50_Q0G336 Cluster: Peptide synthetase; n=1; Fulvimarina
pelagi HTCC2506|Rep: Peptide synthetase - Fulvimarina
pelagi HTCC2506
Length = 1369
Score = 41.1 bits (92), Expect = 0.019
Identities = 31/115 (26%), Positives = 54/115 (46%), Gaps = 5/115 (4%)
Frame = +2
Query: 257 WVGGEMSVCYNAVDR--HVVN---GRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGK 421
W G + S + A +R H+ R + F +H + T+ ++Y EL ++ +R+A
Sbjct: 30 WPGADNSRRWQAGERFHHLFEISCDRFDAFDPLHAAVETEN-STVTYRELDERANRMAHM 88
Query: 422 LTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIHSVVFGGFAARELXTRIEHA 586
L G+ G RV I + + +AMLA ++ G + + GF A + E A
Sbjct: 89 LVETGLEPGGRVAIRLERSADLYVAMLAISKAGGAYVPLDPGFPAERILFICEDA 143
>UniRef50_A5ERA9 Cluster: Arthrofactin synthetase/syringopeptin
synthetase C-related non- ribosomal peptide synthetase
module; n=8; Proteobacteria|Rep: Arthrofactin
synthetase/syringopeptin synthetase C-related non-
ribosomal peptide synthetase module - Bradyrhizobium sp.
(strain BTAi1 / ATCC BAA-1182)
Length = 8646
Score = 41.1 bits (92), Expect = 0.019
Identities = 22/54 (40%), Positives = 30/54 (55%)
Frame = +2
Query: 368 RKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIH 529
R++SY EL Q +RLA L LGV RV I + PE I+ +LA + G +
Sbjct: 1601 RRLSYAELNTQANRLAHHLRKLGVKPDDRVAICIARSPEMIVGLLAILKAGGAY 1654
Score = 41.1 bits (92), Expect = 0.019
Identities = 22/54 (40%), Positives = 30/54 (55%)
Frame = +2
Query: 368 RKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIH 529
R++SY EL Q +RLA L LGV RV I + PE I+ +LA + G +
Sbjct: 6978 RRLSYAELNTQANRLAHHLRKLGVKPDDRVAICIARSPEMIVGLLAILKAGGAY 7031
Score = 40.7 bits (91), Expect = 0.025
Identities = 22/54 (40%), Positives = 30/54 (55%)
Frame = +2
Query: 368 RKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIH 529
R++SY EL Q +RLA L LGV RV I + PE I+ +LA + G +
Sbjct: 521 RRLSYAELNTQANRLAHHLRKLGVKPDDRVAICIERSPEMIVGLLAILKSGGAY 574
Score = 40.7 bits (91), Expect = 0.025
Identities = 22/54 (40%), Positives = 30/54 (55%)
Frame = +2
Query: 368 RKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIH 529
R++SY EL Q +RLA L LGV RV I + PE I+ +LA + G +
Sbjct: 2691 RRLSYAELNTQANRLAHHLRGLGVKPDDRVAICIARSPEMIVGLLAILKAGGAY 2744
Score = 40.7 bits (91), Expect = 0.025
Identities = 22/54 (40%), Positives = 30/54 (55%)
Frame = +2
Query: 368 RKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIH 529
R++SY EL Q +RLA L LGV RV I + PE I+ +LA + G +
Sbjct: 5923 RRLSYAELNTQANRLAHHLRGLGVKPDDRVAICIARSPEMIVGLLAILKAGGAY 5976
Score = 40.7 bits (91), Expect = 0.025
Identities = 22/54 (40%), Positives = 30/54 (55%)
Frame = +2
Query: 368 RKISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIH 529
R++SY EL Q +RLA L LGV RV I + PE I+ +LA + G +
Sbjct: 8068 RRLSYAELNTQANRLAHHLRKLGVRPDDRVAICIARSPEMIVGLLAILKAGGAY 8121
Score = 36.3 bits (80), Expect = 0.53
Identities = 27/84 (32%), Positives = 39/84 (46%)
Frame = +2
Query: 278 VCYNAVDRHVVNGRGEQFALVHDSPLTDTVRKISYNELKDQVSRLAGKLTTLGVSKGARV 457
VC + + + A+VHD R++SY EL + +RLA L LGV RV
Sbjct: 3747 VCVHELFEAQAERTPDAVAVVHDK------RRLSYAELNTEANRLAHHLRKLGVRPDDRV 3800
Query: 458 LIYMPLVPEAIIAMLATNRIGAIH 529
I + E + A LA + GA +
Sbjct: 3801 AICIERSIELVAAELAILKCGAAY 3824
Score = 34.3 bits (75), Expect = 2.1
Identities = 21/53 (39%), Positives = 28/53 (52%)
Frame = +2
Query: 371 KISYNELKDQVSRLAGKLTTLGVSKGARVLIYMPLVPEAIIAMLATNRIGAIH 529
++SY EL Q +RLA L LGV RV I + E + A LA + GA +
Sbjct: 4848 RLSYAELNTQANRLAHHLRKLGVRPDDRVAICIERSIELVAAELAILKCGAAY 4900
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 616,906,654
Number of Sequences: 1657284
Number of extensions: 13299630
Number of successful extensions: 40811
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 38891
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 40659
length of database: 575,637,011
effective HSP length: 97
effective length of database: 414,880,463
effective search space used: 40658285374
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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