Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P12_F_B15
(738 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q8WRT0 Cluster: 3-dehydrecdysone 3b-reductase; n=1; Tri... 263 3e-69
UniRef50_Q9Y020 Cluster: 3-dehydroecdysone 3beta-reductase precu... 197 2e-49
UniRef50_UPI00015B56A2 Cluster: PREDICTED: similar to GA10458-PA... 193 4e-48
UniRef50_UPI00015B56A3 Cluster: PREDICTED: similar to aldo-keto ... 190 3e-47
UniRef50_Q6TY50 Cluster: Reductase 2; n=10; Magnoliophyta|Rep: R... 177 2e-43
UniRef50_Q7JVH6 Cluster: LD24696p; n=2; Sophophora|Rep: LD24696p... 176 5e-43
UniRef50_P14550 Cluster: Alcohol dehydrogenase [NADP+]; n=44; Bi... 174 2e-42
UniRef50_Q01J82 Cluster: OSIGBa0152K17.5 protein; n=28; Magnolio... 170 4e-41
UniRef50_Q2LZ66 Cluster: GA19341-PA; n=2; Endopterygota|Rep: GA1... 169 5e-41
UniRef50_A7SIT3 Cluster: Predicted protein; n=1; Nematostella ve... 169 6e-41
UniRef50_Q01HB5 Cluster: OSIGBa0136O08-OSIGBa0153H12.9 protein; ... 169 8e-41
UniRef50_A3C1Z7 Cluster: Putative uncharacterized protein; n=2; ... 168 1e-40
UniRef50_Q0IBY6 Cluster: Alcohol dehydrogenase; n=2; Chroococcal... 166 4e-40
UniRef50_Q9VTL0 Cluster: CG6083-PA; n=4; Diptera|Rep: CG6083-PA ... 166 4e-40
UniRef50_Q7PCV3 Cluster: ENSANGP00000031808; n=9; Endopterygota|... 166 6e-40
UniRef50_Q17DN0 Cluster: Aldo-keto reductase; n=5; Culicidae|Rep... 165 1e-39
UniRef50_Q41399 Cluster: Chalcone reductase; n=4; eudicotyledons... 163 3e-39
UniRef50_Q1YPE5 Cluster: Aldehyde reductase; n=7; Bacteria|Rep: ... 163 4e-39
UniRef50_A5KSS3 Cluster: Aldehyde reductase; n=1; candidate divi... 163 4e-39
UniRef50_Q7G764 Cluster: Probable NAD(P)H-dependent oxidoreducta... 161 1e-38
UniRef50_A5E082 Cluster: GCY protein; n=4; Saccharomycetales|Rep... 161 2e-38
UniRef50_P45376 Cluster: Aldose reductase; n=21; Bilateria|Rep: ... 161 2e-38
UniRef50_Q8VC28 Cluster: Aldo-keto reductase family 1 member C13... 160 3e-38
UniRef50_Q7QK25 Cluster: ENSANGP00000019775; n=2; Anopheles gamb... 160 4e-38
UniRef50_P26690 Cluster: NAD(P)H-dependent 6'-deoxychalcone synt... 159 9e-38
UniRef50_Q8CI22 Cluster: 2310005E10Rik protein; n=30; Tetrapoda|... 158 1e-37
UniRef50_A3U9Y0 Cluster: Aldehyde reductase; n=5; Bacteroidetes|... 158 2e-37
UniRef50_P15121 Cluster: Aldose reductase; n=72; Eumetazoa|Rep: ... 157 2e-37
UniRef50_Q03TW0 Cluster: Aldo/keto reductase of diketogulonate r... 156 5e-37
UniRef50_Q9FJK0 Cluster: Aldose reductase-like protein; n=3; cor... 154 2e-36
UniRef50_Q4Q5N9 Cluster: Prostaglandin f synthase, putative; n=7... 154 2e-36
UniRef50_A2QBD7 Cluster: Catalytic activity: an alcohol + NADP(+... 154 2e-36
UniRef50_Q7G765 Cluster: Probable NAD(P)H-dependent oxidoreducta... 154 2e-36
UniRef50_Q5BKE9 Cluster: LOC594893 protein; n=5; Xenopus tropica... 153 3e-36
UniRef50_Q4P4P1 Cluster: Putative uncharacterized protein; n=1; ... 153 3e-36
UniRef50_Q8K023 Cluster: Aldo-keto reductase family 1 member C18... 153 3e-36
UniRef50_Q2S340 Cluster: Aldehyde reductase; n=10; Bacteria|Rep:... 153 4e-36
UniRef50_Q54B70 Cluster: Aldehyde reductase; n=2; Dictyostelium ... 153 4e-36
UniRef50_Q16K66 Cluster: Aldo-keto reductase; n=2; Aedes aegypti... 153 4e-36
UniRef50_P22045 Cluster: Probable reductase; n=101; cellular org... 153 6e-36
UniRef50_Q7ZWA4 Cluster: Zgc:56622; n=6; cellular organisms|Rep:... 152 1e-35
UniRef50_UPI0000498F1F Cluster: oxidoreductase, aldo/keto reduct... 150 3e-35
UniRef50_Q88SL1 Cluster: Oxidoreductase; n=51; Lactobacillales|R... 150 3e-35
UniRef50_Q6NII7 Cluster: Putative oxidoreductase; n=2; Corynebac... 150 4e-35
UniRef50_Q23320 Cluster: Putative uncharacterized protein; n=4; ... 150 4e-35
UniRef50_P14065 Cluster: Protein GCY; n=13; Saccharomycetales|Re... 150 4e-35
UniRef50_Q7ZA52 Cluster: Aldose reductase; n=6; Pezizomycotina|R... 149 7e-35
UniRef50_P51857 Cluster: 3-oxo-5-beta-steroid 4-dehydrogenase (E... 147 3e-34
UniRef50_Q0VGY1 Cluster: 3-alpha-hydroxysteroid dehydrogenase; n... 146 4e-34
UniRef50_Q55FL3 Cluster: Aldo-keto reductase; n=2; Dictyostelium... 146 5e-34
UniRef50_Q03XK0 Cluster: Aldo/keto reductase of diketogulonate r... 146 7e-34
UniRef50_Q0PGJ6 Cluster: Aldo-keto reductase; n=32; Magnoliophyt... 145 9e-34
UniRef50_Q9NAI5 Cluster: Putative uncharacterized protein; n=3; ... 145 9e-34
UniRef50_Q10494 Cluster: Probable oxidoreductase C26F1.07; n=2; ... 145 9e-34
UniRef50_Q1U9L6 Cluster: 2,5-didehydrogluconate reductase; n=3; ... 145 1e-33
UniRef50_P27800 Cluster: Aldehyde reductase 1; n=18; root|Rep: A... 145 1e-33
UniRef50_P06632 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 144 2e-33
UniRef50_Q8F1G4 Cluster: Aldehyde reductase; n=8; Bacteria|Rep: ... 144 2e-33
UniRef50_A2EHN6 Cluster: Oxidoreductase, aldo/keto reductase fam... 144 2e-33
UniRef50_Q5KI95 Cluster: Aldo-keto reductase, putative; n=14; Di... 144 2e-33
UniRef50_A1D4E3 Cluster: D-xylose reductase (Xyl1), putative; n=... 144 2e-33
UniRef50_P23901 Cluster: Aldose reductase; n=9; Poaceae|Rep: Ald... 144 2e-33
UniRef50_P28475 Cluster: NADP-dependent D-sorbitol-6-phosphate d... 144 3e-33
UniRef50_A7CWF9 Cluster: Aldehyde reductase; n=2; Bacteria|Rep: ... 143 5e-33
UniRef50_Q7PLK6 Cluster: CG40064-PA; n=1; Drosophila melanogaste... 143 5e-33
UniRef50_Q02198 Cluster: Morphine 6-dehydrogenase; n=5; Bacteria... 143 5e-33
UniRef50_Q7N0E4 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 142 6e-33
UniRef50_Q41E86 Cluster: 2,5-didehydrogluconate reductase; n=2; ... 142 6e-33
UniRef50_Q96UH3 Cluster: Aldehyde reductase; n=13; Pezizomycotin... 142 8e-33
UniRef50_UPI0000588153 Cluster: PREDICTED: hypothetical protein;... 141 1e-32
UniRef50_A4RQH8 Cluster: Predicted protein; n=2; Ostreococcus|Re... 141 1e-32
UniRef50_A7RRF6 Cluster: Predicted protein; n=2; Nematostella ve... 141 1e-32
UniRef50_Q8ZI40 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 141 1e-32
UniRef50_UPI0000E4A7CE Cluster: PREDICTED: similar to LOC553452 ... 140 2e-32
UniRef50_Q05KR9 Cluster: Benzil reductase; n=5; Bacillales|Rep: ... 140 2e-32
UniRef50_Q5FK98 Cluster: Oxidoreductase; n=8; Lactobacillales|Re... 140 4e-32
UniRef50_A2R6Z3 Cluster: Catalytic activity: an alcohol + NADP(+... 140 4e-32
UniRef50_A1UEC5 Cluster: 2,5-didehydrogluconate reductase; n=20;... 139 6e-32
UniRef50_Q968S3 Cluster: Aldoketoreductase-like protein; n=1; Or... 139 6e-32
UniRef50_Q9HGY0 Cluster: Glycerol dehydrogenase; n=8; Saccharomy... 138 2e-31
UniRef50_Q4JX70 Cluster: Putative oxidoreductase; n=1; Corynebac... 137 2e-31
UniRef50_Q28P63 Cluster: Aldo/keto reductase; n=4; Rhodobacterac... 137 2e-31
UniRef50_P38715 Cluster: NADPH-dependent aldose reductase GRE3; ... 137 2e-31
UniRef50_Q17G72 Cluster: Aldo-keto reductase; n=9; Endopterygota... 136 4e-31
UniRef50_Q6CFG7 Cluster: Yarrowia lipolytica chromosome B of str... 136 4e-31
UniRef50_Q1IN88 Cluster: Aldehyde reductase; n=5; Bacteria|Rep: ... 136 5e-31
UniRef50_A6RKL9 Cluster: Putative uncharacterized protein; n=3; ... 136 5e-31
UniRef50_A6WDZ5 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:... 136 7e-31
UniRef50_A2FPE2 Cluster: Oxidoreductase, aldo/keto reductase fam... 136 7e-31
UniRef50_Q9ZBW7 Cluster: Putative oxidoreductase; n=2; Actinomyc... 135 9e-31
UniRef50_A0JRJ3 Cluster: 2,5-didehydrogluconate reductase; n=3; ... 135 1e-30
UniRef50_Q2V420 Cluster: Uncharacterized protein At2g37770.1; n=... 135 1e-30
UniRef50_Q8J0K1 Cluster: 4-dihydromethyltrisporate dehydrogenase... 135 1e-30
UniRef50_UPI000023D0F1 Cluster: hypothetical protein FG03517.1; ... 134 2e-30
UniRef50_A7CUW0 Cluster: 2,5-didehydrogluconate reductase; n=6; ... 134 2e-30
UniRef50_Q7PM68 Cluster: ENSANGP00000014386; n=1; Anopheles gamb... 134 2e-30
UniRef50_Q68ST9 Cluster: Reductase AKOR2; n=2; Pleurotus djamor|... 134 2e-30
UniRef50_A6ESC0 Cluster: ARA1; n=1; unidentified eubacterium SCB... 133 4e-30
UniRef50_A0JRJ6 Cluster: Aldo/keto reductase; n=2; Micrococcinea... 133 5e-30
UniRef50_Q235V6 Cluster: Oxidoreductase, aldo/keto reductase fam... 133 5e-30
UniRef50_Q1VRG6 Cluster: YvgN; n=1; Psychroflexus torquis ATCC 7... 132 7e-30
UniRef50_Q9U2J5 Cluster: Putative uncharacterized protein; n=2; ... 132 7e-30
UniRef50_Q927P9 Cluster: Lin2739 protein; n=12; Bacteria|Rep: Li... 132 9e-30
UniRef50_Q8Y463 Cluster: Lmo2592 protein; n=40; Bacteria|Rep: Lm... 132 1e-29
UniRef50_A6W8E7 Cluster: 2,5-didehydrogluconate reductase; n=3; ... 132 1e-29
UniRef50_Q17DN1 Cluster: Aldo-keto reductase; n=1; Aedes aegypti... 132 1e-29
UniRef50_UPI00015B5BD7 Cluster: PREDICTED: similar to aldo-keto ... 131 2e-29
UniRef50_Q83N50 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 131 2e-29
UniRef50_UPI00006CD296 Cluster: oxidoreductase, aldo/keto reduct... 131 2e-29
UniRef50_Q8G7K9 Cluster: Dehydrogenase or reductase protein; n=4... 131 2e-29
UniRef50_Q4PAT5 Cluster: Putative uncharacterized protein; n=1; ... 131 2e-29
UniRef50_Q568D7 Cluster: Zgc:110366; n=7; Euteleostomi|Rep: Zgc:... 130 3e-29
UniRef50_Q9X0A2 Cluster: Oxidoreductase, aldo/keto reductase fam... 130 3e-29
UniRef50_Q9VHX4 Cluster: CG2767-PA; n=4; Endopterygota|Rep: CG27... 130 3e-29
UniRef50_UPI0000E45E29 Cluster: PREDICTED: similar to aldose red... 130 3e-29
UniRef50_UPI0000499B0E Cluster: oxidoreductase, aldo/keto reduct... 130 3e-29
UniRef50_Q838E0 Cluster: Oxidoreductase, aldo/keto reductase fam... 130 3e-29
UniRef50_A5ZYE6 Cluster: Putative uncharacterized protein; n=1; ... 130 3e-29
UniRef50_P38115 Cluster: D-arabinose dehydrogenase [NAD(P)+] hea... 130 3e-29
UniRef50_UPI0000D9A956 Cluster: PREDICTED: similar to aldo-keto ... 130 5e-29
UniRef50_Q4V008 Cluster: Oxidoreductase; n=4; Proteobacteria|Rep... 129 8e-29
UniRef50_UPI00015B4B22 Cluster: PREDICTED: similar to GA15457-PA... 128 1e-28
UniRef50_Q1RFP0 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 128 1e-28
UniRef50_A2QVE5 Cluster: Similarity: shows similarity to several... 128 1e-28
UniRef50_Q7NB44 Cluster: ARA1; n=3; Firmicutes|Rep: ARA1 - Mycop... 128 1e-28
UniRef50_Q24C22 Cluster: Oxidoreductase, aldo/keto reductase fam... 128 1e-28
UniRef50_Q2UGR1 Cluster: Aldo/keto reductase family proteins; n=... 128 1e-28
UniRef50_Q0SFM4 Cluster: Probable 2,5-didehydrogluconate reducta... 127 2e-28
UniRef50_A6NPD6 Cluster: Putative uncharacterized protein; n=3; ... 127 2e-28
UniRef50_P47137 Cluster: Probable oxidoreductase YJR096W; n=8; S... 127 2e-28
UniRef50_Q22352 Cluster: Putative uncharacterized protein T08H10... 127 3e-28
UniRef50_P15339 Cluster: 2,5-diketo-D-gluconic acid reductase B;... 126 4e-28
UniRef50_A7PNI3 Cluster: Chromosome chr1 scaffold_22, whole geno... 126 6e-28
UniRef50_Q7QVQ9 Cluster: GLP_302_44328_45269; n=1; Giardia lambl... 126 6e-28
UniRef50_Q6F7K7 Cluster: 2,5-diketo-D-gluconate reductase; n=20;... 126 7e-28
UniRef50_A2UAH0 Cluster: Aldo/keto reductase; n=1; Bacillus coag... 126 7e-28
UniRef50_A5PDA8 Cluster: Putative oxidoreductase protein; n=1; E... 125 1e-27
UniRef50_Q8SSK6 Cluster: ALDOSE REDUCTASE; n=1; Encephalitozoon ... 125 1e-27
UniRef50_O13848 Cluster: NADH/NADPH dependent indole-3-acetaldeh... 125 1e-27
UniRef50_Q927E1 Cluster: Lin2848 protein; n=13; Listeria|Rep: Li... 124 2e-27
UniRef50_Q6C2L0 Cluster: Yarrowia lipolytica chromosome F of str... 124 2e-27
UniRef50_Q88TV9 Cluster: Oxidoreductase; n=4; Lactobacillus|Rep:... 124 3e-27
UniRef50_Q7WSY4 Cluster: Putative aldo-keto reductase; n=1; Prop... 124 3e-27
UniRef50_A3VHZ9 Cluster: Oxidoreductase; n=1; Rhodobacterales ba... 123 4e-27
UniRef50_Q9ZUJ6 Cluster: T2K10.1 protein; n=16; core eudicotyled... 123 4e-27
UniRef50_UPI00006CA3CB Cluster: oxidoreductase, aldo/keto reduct... 123 5e-27
UniRef50_Q5HR31 Cluster: Oxidoreductase, aldo/keto reductase fam... 123 5e-27
UniRef50_A2EYY6 Cluster: Oxidoreductase, aldo/keto reductase fam... 123 5e-27
UniRef50_Q8ET73 Cluster: 2,5-diketo-D-gluconate reductase; n=12;... 122 7e-27
UniRef50_Q15NA5 Cluster: Aldo/keto reductase; n=2; Gammaproteoba... 122 7e-27
UniRef50_A0JX62 Cluster: 2,5-didehydrogluconate reductase; n=9; ... 122 7e-27
UniRef50_Q4PDR0 Cluster: Putative uncharacterized protein; n=1; ... 122 7e-27
UniRef50_UPI0000DB6EE9 Cluster: PREDICTED: similar to C35D10.6; ... 122 9e-27
UniRef50_Q929C8 Cluster: Lin2349 protein; n=12; Listeria|Rep: Li... 122 1e-26
UniRef50_A5VK30 Cluster: 2,5-didehydrogluconate reductase; n=2; ... 122 1e-26
UniRef50_Q5FK99 Cluster: Oxidoreductase aldo-keto reductase fami... 121 2e-26
UniRef50_Q6U5V3 Cluster: Putative uncharacterized protein; n=1; ... 121 2e-26
UniRef50_Q54NR2 Cluster: Aldo-keto reductase; n=3; Dictyostelium... 121 2e-26
UniRef50_UPI00015B40FA Cluster: PREDICTED: similar to CG2767-PA;... 120 3e-26
UniRef50_UPI00006CCCD7 Cluster: oxidoreductase, aldo/keto reduct... 120 3e-26
UniRef50_Q890A0 Cluster: Oxidoreductase; n=6; Lactobacillales|Re... 120 3e-26
UniRef50_Q5FLI5 Cluster: Aldehyde reductase; n=2; Bacteria|Rep: ... 120 3e-26
UniRef50_Q1M4Z6 Cluster: Putative aldo-keto reductase/oxidase; n... 120 3e-26
UniRef50_A3LTU8 Cluster: D-arabinose dehydrogenase; n=5; Sacchar... 120 3e-26
UniRef50_A3JU52 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 120 4e-26
UniRef50_Q6RZX1 Cluster: Gld1; n=22; Pezizomycotina|Rep: Gld1 - ... 120 5e-26
UniRef50_UPI00015B4912 Cluster: PREDICTED: similar to aldo-keto ... 119 6e-26
UniRef50_Q03PG5 Cluster: Aldo/keto reductase of diketogulonate r... 119 9e-26
UniRef50_Q2U219 Cluster: Aldo/keto reductase family proteins; n=... 119 9e-26
UniRef50_A7ALH6 Cluster: Putative uncharacterized protein; n=1; ... 118 1e-25
UniRef50_Q5FT75 Cluster: Putative 2,5-diketo-D-gluconic acid red... 118 2e-25
UniRef50_Q11BF8 Cluster: Aldo/keto reductase; n=12; Bacteria|Rep... 118 2e-25
UniRef50_Q5BLA6 Cluster: Zgc:110782; n=2; Danio rerio|Rep: Zgc:1... 117 3e-25
UniRef50_A6LZ55 Cluster: 2,5-didehydrogluconate reductase; n=1; ... 117 3e-25
UniRef50_A0AWM8 Cluster: Aldo/keto reductase; n=4; Actinomycetal... 117 3e-25
UniRef50_Q89JN4 Cluster: Oxidoreductase; n=8; Rhizobiales|Rep: O... 117 3e-25
UniRef50_Q03X85 Cluster: Aldo/keto reductase of diketogulonate r... 117 3e-25
UniRef50_Q9P6D3 Cluster: Related to aldo-keto reductase YPR1; n=... 117 3e-25
UniRef50_Q043M4 Cluster: Aldo/keto reductase of diketogulonate r... 116 6e-25
UniRef50_A7P424 Cluster: Chromosome chr1 scaffold_5, whole genom... 116 8e-25
UniRef50_A7BA05 Cluster: Putative uncharacterized protein; n=1; ... 115 1e-24
UniRef50_A6RMS0 Cluster: Putative uncharacterized protein; n=1; ... 115 1e-24
UniRef50_A3UJS6 Cluster: Oxidoreductase; n=3; Alphaproteobacteri... 115 1e-24
UniRef50_Q4PHK0 Cluster: Putative uncharacterized protein; n=1; ... 106 2e-24
UniRef50_Q75E75 Cluster: ABL209Cp; n=1; Eremothecium gossypii|Re... 114 2e-24
UniRef50_Q5FKI1 Cluster: Reductase-dehydrogenase; n=1; Lactobaci... 113 3e-24
UniRef50_A3VRL4 Cluster: Putative uncharacterized protein; n=1; ... 113 3e-24
UniRef50_Q8ZH36 Cluster: 2,5-diketo-D-gluconic acid reductase B;... 113 4e-24
UniRef50_UPI0000D56CE5 Cluster: PREDICTED: similar to CG6084-PA,... 113 6e-24
UniRef50_Q7VG53 Cluster: Aldo-keto reductase; n=28; Bacteria|Rep... 113 6e-24
UniRef50_Q5TNP1 Cluster: ENSANGP00000029046; n=2; Culicidae|Rep:... 112 1e-23
UniRef50_Q5K8C5 Cluster: Aldo-keto reductase, putative; n=1; Fil... 112 1e-23
UniRef50_Q1DLF1 Cluster: Putative uncharacterized protein; n=1; ... 112 1e-23
UniRef50_Q572D2 Cluster: Aldo-keto reductase, putative; n=1; Phy... 111 1e-23
UniRef50_Q7XY49 Cluster: Mannose 6-phosphate reductase; n=1; Gri... 100 2e-23
UniRef50_Q9A2X8 Cluster: Oxidoreductase, aldo/keto reductase fam... 111 2e-23
UniRef50_Q18483 Cluster: Putative uncharacterized protein; n=2; ... 111 2e-23
UniRef50_A5DRJ6 Cluster: Putative uncharacterized protein; n=4; ... 111 2e-23
UniRef50_P91997 Cluster: Putative uncharacterized protein; n=4; ... 110 3e-23
UniRef50_Q96JD6 Cluster: Aldo-keto reductase family 1 member C-l... 110 3e-23
UniRef50_A7SGW6 Cluster: Predicted protein; n=1; Nematostella ve... 110 4e-23
UniRef50_O14088 Cluster: Xylose and arabinose reductase; n=1; Sc... 110 4e-23
UniRef50_UPI0000519CC2 Cluster: PREDICTED: similar to CG2767-PA;... 109 5e-23
UniRef50_Q3E9M9 Cluster: Uncharacterized protein At5g01670.2; n=... 109 5e-23
UniRef50_Q5T2L2 Cluster: Aldo-keto reductase family 1 member C-l... 109 5e-23
UniRef50_Q5NLW3 Cluster: Putative oxidoreductase; n=1; Zymomonas... 109 7e-23
UniRef50_Q3CZS2 Cluster: Oxidoreductase, aldo/keto reductase fam... 109 7e-23
UniRef50_Q11DV1 Cluster: Aldo/keto reductase; n=10; Alphaproteob... 109 9e-23
UniRef50_Q9P734 Cluster: Related to 2, 5-diketo-D-gluconic acid ... 109 9e-23
UniRef50_Q5XJM7 Cluster: Zgc:101765; n=5; Eumetazoa|Rep: Zgc:101... 108 2e-22
UniRef50_A0L1A2 Cluster: Aldo/keto reductase; n=8; Gammaproteoba... 108 2e-22
UniRef50_Q68A33 Cluster: Aldo-keto reductase 1a; n=1; Ciona inte... 108 2e-22
UniRef50_A2QB88 Cluster: Contig An01c0460, complete genome. prec... 108 2e-22
UniRef50_Q76L37 Cluster: Conjugated polyketone reductase C1; n=3... 107 2e-22
UniRef50_Q2CAL9 Cluster: 2,5-didehydrogluconate reductase; n=2; ... 107 3e-22
UniRef50_A2QL02 Cluster: Putative frameshift; n=1; Aspergillus n... 107 3e-22
UniRef50_A4YQ04 Cluster: 2,5-diketo-D-gluconate reductase B; n=1... 107 4e-22
UniRef50_Q5UX52 Cluster: Oxidoreductase aldo/keto reductase fami... 107 4e-22
UniRef50_Q0CLQ2 Cluster: Putative uncharacterized protein; n=1; ... 106 6e-22
UniRef50_Q8EUH6 Cluster: Oxidoreductase; n=1; Mycoplasma penetra... 105 9e-22
UniRef50_Q09632 Cluster: Probable oxidoreductase ZK1290.5; n=2; ... 105 1e-21
UniRef50_P70883 Cluster: AkrI; n=1; Butyrivibrio fibrisolvens|Re... 105 1e-21
UniRef50_A3T261 Cluster: Putative uncharacterized protein; n=1; ... 105 1e-21
UniRef50_Q6CEJ0 Cluster: Yarrowia lipolytica chromosome B of str... 104 2e-21
UniRef50_A3WP89 Cluster: Aldo/keto reductase; n=1; Idiomarina ba... 103 3e-21
UniRef50_Q17568 Cluster: Putative uncharacterized protein; n=1; ... 103 3e-21
UniRef50_Q1Q8W8 Cluster: Aldo/keto reductase; n=1; Psychrobacter... 103 5e-21
UniRef50_Q00XM4 Cluster: Aldo/keto reductase family proteins; n=... 103 5e-21
UniRef50_Q4WUF7 Cluster: Aldo-keto reductase, putative; n=3; Pez... 103 5e-21
UniRef50_Q2BBN7 Cluster: YvgN; n=1; Bacillus sp. NRRL B-14911|Re... 103 6e-21
UniRef50_Q21274 Cluster: Putative uncharacterized protein; n=1; ... 103 6e-21
UniRef50_Q9C1X5 Cluster: Xylose and arabinose reductase; n=1; Sc... 103 6e-21
UniRef50_Q4P1G1 Cluster: Putative uncharacterized protein; n=1; ... 103 6e-21
UniRef50_A1CAM7 Cluster: Aldo-keto reductase, putative; n=9; Dik... 102 8e-21
UniRef50_UPI000065D0BD Cluster: Homolog of Homo sapiens "AKR1B1 ... 102 1e-20
UniRef50_Q7VHE1 Cluster: Putative uncharacterized protein; n=1; ... 102 1e-20
UniRef50_Q03U37 Cluster: Aldo/keto reductase of diketogulonate r... 102 1e-20
UniRef50_Q4FY75 Cluster: Aldo-keto reductase-like protein; n=5; ... 102 1e-20
UniRef50_Q0CK00 Cluster: Predicted protein; n=1; Aspergillus ter... 101 1e-20
UniRef50_Q07551 Cluster: NADPH-dependent alpha-keto amide reduct... 101 1e-20
UniRef50_Q4PE96 Cluster: Putative uncharacterized protein; n=1; ... 101 2e-20
UniRef50_Q14LA8 Cluster: Putative aldo/keto reductase oxidoreduc... 101 2e-20
UniRef50_Q5V663 Cluster: Aldehyde reductase; n=6; Halobacteriace... 100 3e-20
UniRef50_Q5UYI9 Cluster: Oxidoreductase; n=1; Haloarcula marismo... 99 6e-20
UniRef50_Q7R2T6 Cluster: GLP_291_56367_57278; n=1; Giardia lambl... 100 7e-20
UniRef50_A7D6I8 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 99 1e-19
UniRef50_A7D6Q0 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 99 1e-19
UniRef50_Q9X265 Cluster: Oxidoreductase, aldo/keto reductase fam... 97 4e-19
UniRef50_Q9HM42 Cluster: Alcohol dehydrogenase related protein; ... 97 4e-19
UniRef50_Q96JD6-2 Cluster: Isoform 2 of Q96JD6 ; n=4; Catarrhini... 97 5e-19
UniRef50_Q6WGK4 Cluster: Aldose reductase; n=1; Pristionchus pac... 97 5e-19
UniRef50_Q76L36 Cluster: Conjugated polyketone reductase C2; n=1... 97 5e-19
UniRef50_A7TLC4 Cluster: Putative uncharacterized protein; n=1; ... 96 9e-19
UniRef50_A7BES9 Cluster: Putative uncharacterized protein; n=1; ... 95 1e-18
UniRef50_Q4DJ59 Cluster: Aldo/keto reductase, putative; n=2; Try... 95 2e-18
UniRef50_Q5V6N9 Cluster: Alcohol dehydrogenase; n=2; Halobacteri... 94 4e-18
UniRef50_A1RB46 Cluster: 2,5-diketo-D-gluconate reductase; n=1; ... 93 5e-18
UniRef50_Q5KKZ8 Cluster: Aldo-keto reductase, putative; n=2; Fil... 93 5e-18
UniRef50_A6VNW9 Cluster: Aldo/keto reductase precursor; n=1; Act... 93 6e-18
UniRef50_Q5V1M9 Cluster: Oxidoreductase aldo/keto reductase fami... 93 9e-18
UniRef50_A7D7K7 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 92 1e-17
UniRef50_Q16CS5 Cluster: 2,5-diketo-D-gluconic acid reductase B,... 91 3e-17
UniRef50_Q8EVS8 Cluster: Oxidoreductase; n=1; Mycoplasma penetra... 90 5e-17
UniRef50_Q2H7A8 Cluster: Putative uncharacterized protein; n=1; ... 89 8e-17
UniRef50_Q979I4 Cluster: Aldo / keto reductase; n=3; Archaea|Rep... 89 8e-17
UniRef50_UPI000023DF27 Cluster: hypothetical protein FG07276.1; ... 89 1e-16
UniRef50_Q11B35 Cluster: Aldo/keto reductase; n=1; Mesorhizobium... 89 1e-16
UniRef50_A7D761 Cluster: Aldo/keto reductase; n=2; Halobacteriac... 89 1e-16
UniRef50_A2RMU6 Cluster: Oxidoreductase, aldo/keto reductase fam... 89 1e-16
UniRef50_A5BF24 Cluster: Putative uncharacterized protein; n=1; ... 89 1e-16
UniRef50_Q6CGE9 Cluster: Similar to sp|P47137 Saccharomyces cere... 88 2e-16
UniRef50_Q5KD52 Cluster: Oxidoreductase, putative; n=1; Filobasi... 88 2e-16
UniRef50_A6QXT4 Cluster: Predicted protein; n=1; Ajellomyces cap... 88 2e-16
UniRef50_Q5KCN9 Cluster: Putative uncharacterized protein; n=1; ... 87 3e-16
UniRef50_A7RUA2 Cluster: Predicted protein; n=1; Nematostella ve... 87 4e-16
UniRef50_Q5V398 Cluster: Oxidoreductase aldo/keto reductase fami... 87 4e-16
UniRef50_A4FEB9 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 87 6e-16
UniRef50_A6SI80 Cluster: Putative uncharacterized protein; n=1; ... 86 7e-16
UniRef50_Q59ZT1 Cluster: Putative uncharacterized protein; n=1; ... 86 1e-15
UniRef50_Q6L139 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 86 1e-15
UniRef50_Q8EVT8 Cluster: Oxidoreductase-aldo/keto reductase fami... 85 1e-15
UniRef50_Q64UK5 Cluster: Aldo/keto reductase family oxidoreducta... 85 2e-15
UniRef50_A4IJ00 Cluster: LOC548351 protein; n=1; Xenopus tropica... 62 3e-15
UniRef50_A3LWP0 Cluster: Aldo/keto reductase; n=7; Saccharomycet... 84 4e-15
UniRef50_Q8EUX1 Cluster: Aldo/keto reductase family oxidoreducta... 83 5e-15
UniRef50_Q9USV2 Cluster: Xylose and arabinose reductase; n=2; Sc... 83 7e-15
UniRef50_Q59Z55 Cluster: Potential aldo/keto reductase; n=6; Sac... 83 9e-15
UniRef50_Q4JCC1 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 83 9e-15
UniRef50_Q4WP69 Cluster: Aldehyde reductase, putative; n=1; Aspe... 82 1e-14
UniRef50_UPI000155CAC7 Cluster: PREDICTED: hypothetical protein;... 82 2e-14
UniRef50_A6PR52 Cluster: Aldo/keto reductase; n=1; Victivallis v... 82 2e-14
UniRef50_Q013C5 Cluster: Glycerol dehydrogenase, putative; n=2; ... 82 2e-14
UniRef50_Q14LU6 Cluster: Putative aldo/keto reductase oxidoreduc... 81 2e-14
UniRef50_UPI000038E317 Cluster: hypothetical protein Faci_030017... 80 6e-14
UniRef50_Q4WI64 Cluster: Aldehyde reductase, putative; n=22; Pez... 80 6e-14
UniRef50_Q1PV10 Cluster: Putative uncharacterized protein; n=1; ... 78 2e-13
UniRef50_Q7M4N1 Cluster: Dihydrodiol dehydrogenase DD2; n=2; Hom... 78 2e-13
UniRef50_Q97U17 Cluster: Oxidoreductase, aldo/keto reductase fam... 78 3e-13
UniRef50_Q391C9 Cluster: Aldo/keto reductase; n=10; Proteobacter... 77 5e-13
UniRef50_Q61U89 Cluster: Putative uncharacterized protein CBG054... 77 5e-13
UniRef50_A5AD50 Cluster: Putative uncharacterized protein; n=3; ... 77 6e-13
UniRef50_Q4Q973 Cluster: Aldo/keto reductase, putative; n=3; Lei... 77 6e-13
UniRef50_Q8DK16 Cluster: Tlr1054 protein; n=6; Cyanobacteria|Rep... 76 1e-12
UniRef50_Q6CWB9 Cluster: Similarities with sp|Q12458 Saccharomyc... 74 4e-12
UniRef50_Q5B5R6 Cluster: Putative uncharacterized protein; n=1; ... 73 6e-12
UniRef50_Q97V56 Cluster: Dehydrogenase; n=8; Thermoprotei|Rep: D... 73 7e-12
UniRef50_A7EW94 Cluster: Putative uncharacterized protein; n=1; ... 72 1e-11
UniRef50_Q89RG2 Cluster: Aldo/keto reductase; n=11; Bacteria|Rep... 71 2e-11
UniRef50_A3DNU7 Cluster: Aldo/keto reductase; n=3; Desulfurococc... 71 2e-11
UniRef50_Q0GU15 Cluster: ORF28; n=3; Bacteria|Rep: ORF28 - Lacto... 71 3e-11
UniRef50_Q9V2P1 Cluster: Myo-inositol degradation; n=5; Archaea|... 71 3e-11
UniRef50_A3H9Y8 Cluster: Aldo/keto reductase; n=2; Caldivirga ma... 71 3e-11
UniRef50_Q8ZU65 Cluster: Aldo-keto reductase, putative; n=4; The... 71 4e-11
UniRef50_Q03BE0 Cluster: Aldo/keto reductase family enzyme; n=5;... 70 7e-11
UniRef50_Q5KKC5 Cluster: Putative uncharacterized protein; n=2; ... 69 9e-11
UniRef50_Q67NQ1 Cluster: Oxidoreductase; n=1; Symbiobacterium th... 69 1e-10
UniRef50_A7LSN6 Cluster: Putative uncharacterized protein; n=3; ... 67 4e-10
UniRef50_Q5B034 Cluster: Putative uncharacterized protein; n=1; ... 67 4e-10
UniRef50_A7HEV1 Cluster: Aldo/keto reductase; n=13; Bacteria|Rep... 66 6e-10
UniRef50_Q2H1Q3 Cluster: Putative uncharacterized protein; n=1; ... 65 1e-09
UniRef50_UPI00005F9591 Cluster: COG0656: Aldo/keto reductases, r... 64 3e-09
UniRef50_Q93KW0 Cluster: Putative oxidoreductase; n=1; Streptomy... 64 3e-09
UniRef50_A5BYJ4 Cluster: Putative uncharacterized protein; n=1; ... 64 3e-09
UniRef50_A4RPC9 Cluster: Putative uncharacterized protein; n=1; ... 64 3e-09
UniRef50_Q97UV9 Cluster: Oxidoreductase; n=1; Sulfolobus solfata... 64 3e-09
UniRef50_Q9C2J8 Cluster: Related to D-xylose reductase II, III p... 64 3e-09
UniRef50_Q64W37 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 64 5e-09
UniRef50_Q0DHN0 Cluster: Os05g0456200 protein; n=2; Oryza sativa... 64 5e-09
UniRef50_A6X3I0 Cluster: Aldo/keto reductase; n=3; Bacteria|Rep:... 63 8e-09
UniRef50_Q5KPU6 Cluster: Putative uncharacterized protein; n=2; ... 63 8e-09
UniRef50_Q5FHT2 Cluster: Aldehyde reductase; n=4; Lactobacillus|... 62 1e-08
UniRef50_A4M6J9 Cluster: Aldo/keto reductase; n=1; Petrotoga mob... 62 1e-08
UniRef50_Q0TYC7 Cluster: Predicted protein; n=1; Phaeosphaeria n... 62 1e-08
UniRef50_Q81RN9 Cluster: Oxidoreductase, aldo/keto reductase fam... 62 2e-08
UniRef50_Q7NK63 Cluster: Gll1617 protein; n=1; Gloeobacter viola... 62 2e-08
UniRef50_Q5ZTU6 Cluster: D-xylose reductase III; n=5; Legionella... 62 2e-08
UniRef50_A0VAL7 Cluster: Aldo/keto reductase; n=2; Proteobacteri... 61 2e-08
UniRef50_A2G4I3 Cluster: Oxidoreductase, aldo/keto reductase fam... 61 2e-08
UniRef50_Q18903 Cluster: Putative uncharacterized protein C56G3.... 61 3e-08
UniRef50_Q3I1P2 Cluster: Aldo-keto oxidoreductase; n=6; Bacteria... 60 4e-08
UniRef50_P91021 Cluster: Putative uncharacterized protein; n=1; ... 60 4e-08
UniRef50_Q8G7F7 Cluster: Possible oxidoreductase of the aldo/ket... 60 6e-08
UniRef50_Q88SS2 Cluster: Oxidoreductase; n=13; Firmicutes|Rep: O... 60 6e-08
UniRef50_A6XQ31 Cluster: Putative uncharacterized protein; n=1; ... 60 6e-08
UniRef50_P46905 Cluster: Uncharacterized oxidoreductase yccK; n=... 60 6e-08
UniRef50_P80874 Cluster: General stress protein 69; n=16; cellul... 60 7e-08
UniRef50_Q1IQ78 Cluster: Aldo/keto reductase; n=1; Acidobacteria... 59 1e-07
UniRef50_A2UBC7 Cluster: Aldo/keto reductase; n=3; cellular orga... 59 1e-07
UniRef50_A4QYG8 Cluster: Putative uncharacterized protein; n=1; ... 59 1e-07
UniRef50_Q88TP1 Cluster: Oxidoreductase; n=3; Bacteria|Rep: Oxid... 59 1e-07
UniRef50_A0LJ47 Cluster: Aldo/keto reductase; n=1; Syntrophobact... 59 1e-07
UniRef50_Q3WFS8 Cluster: Aldo/keto reductase; n=1; Frankia sp. E... 58 2e-07
UniRef50_A6BIJ0 Cluster: Putative uncharacterized protein; n=1; ... 58 2e-07
UniRef50_Q1U6R9 Cluster: Aldo/keto reductase; n=25; Bacilli|Rep:... 58 2e-07
UniRef50_A7BLU0 Cluster: Aldo/keto reductase family; n=1; Beggia... 58 2e-07
UniRef50_A6WAE5 Cluster: Aldo/keto reductase; n=1; Kineococcus r... 58 2e-07
UniRef50_Q8PN61 Cluster: Oxidoreductase; n=5; Proteobacteria|Rep... 58 3e-07
UniRef50_Q21EY6 Cluster: Aldo/keto reductase; n=1; Saccharophagu... 58 3e-07
UniRef50_A0K203 Cluster: Aldo/keto reductase; n=2; Arthrobacter|... 58 3e-07
UniRef50_UPI0000DAE567 Cluster: hypothetical protein Rgryl_01000... 57 4e-07
UniRef50_A5VEK4 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:... 57 4e-07
UniRef50_Q55ML8 Cluster: Putative uncharacterized protein; n=2; ... 57 4e-07
UniRef50_P77735 Cluster: Uncharacterized oxidoreductase yajO; n=... 57 4e-07
UniRef50_Q8YAN3 Cluster: Lmo0084 protein; n=11; Listeria monocyt... 57 5e-07
UniRef50_Q2FGN2 Cluster: Oxidoreductase, aldo/keto reductase fam... 57 5e-07
UniRef50_Q034L5 Cluster: Aryl-alcohol dehydrogenase related enzy... 57 5e-07
UniRef50_P76234 Cluster: Uncharacterized protein yeaE; n=39; Bac... 57 5e-07
UniRef50_Q94A68 Cluster: Uncharacterized oxidoreductase At1g0669... 57 5e-07
UniRef50_Q4WF80 Cluster: Glycerol dehydrogenase (GCY1), putative... 56 7e-07
UniRef50_A1CHK2 Cluster: Aldose 1-epimerase, putative; n=11; Pez... 56 7e-07
UniRef50_Q49V75 Cluster: Putative oxidoreductase; n=1; Staphyloc... 56 1e-06
UniRef50_UPI000023DAA9 Cluster: hypothetical protein FG00321.1; ... 55 2e-06
UniRef50_Q60BI7 Cluster: Oxidoreductase, aldo/keto reductase fam... 55 2e-06
UniRef50_Q2JHT1 Cluster: Aldo/keto reductase Tas; n=25; cellular... 55 2e-06
UniRef50_Q1GSJ8 Cluster: Aldo/keto reductase; n=3; Sphingomonada... 55 2e-06
UniRef50_A5FAZ9 Cluster: Aldo/keto reductase; n=1; Flavobacteriu... 55 2e-06
UniRef50_Q6TRS1 Cluster: Oxidoreductase; n=1; Ustilago maydis|Re... 55 2e-06
UniRef50_A6QVW8 Cluster: Predicted protein; n=1; Ajellomyces cap... 55 2e-06
UniRef50_Q8YXI8 Cluster: All1225 protein; n=9; Cyanobacteria|Rep... 55 2e-06
UniRef50_Q8UIN0 Cluster: Oxidoreductase; n=3; Alphaproteobacteri... 55 2e-06
UniRef50_Q660Z5 Cluster: Aldose reductase, putative; n=3; Borrel... 55 2e-06
UniRef50_Q3WEJ4 Cluster: Aldo/keto reductase; n=9; Bacteria|Rep:... 55 2e-06
UniRef50_Q1GHE2 Cluster: Aldo/keto reductase; n=8; Alphaproteoba... 55 2e-06
UniRef50_Q0LKQ4 Cluster: Aldo/keto reductase; n=1; Herpetosiphon... 55 2e-06
UniRef50_A0RYR0 Cluster: Oxidoreductase; n=2; cellular organisms... 55 2e-06
UniRef50_P82125 Cluster: 1,5-anhydro-D-fructose reductase; n=1; ... 55 2e-06
UniRef50_Q89JX0 Cluster: Oxidoreductase; n=26; Bacteria|Rep: Oxi... 54 3e-06
UniRef50_Q09D95 Cluster: Ydhf chain A; n=1; Stigmatella aurantia... 54 3e-06
UniRef50_Q08NK7 Cluster: Aldo/keto reductase; n=1; Stigmatella a... 54 3e-06
UniRef50_A6SJ74 Cluster: Putative uncharacterized protein; n=1; ... 54 3e-06
UniRef50_Q8ZXA1 Cluster: Aldo-keto reductase family protein; n=3... 54 3e-06
UniRef50_Q74DE6 Cluster: Oxidoreductase, aldo/keto reductase fam... 54 4e-06
UniRef50_A7AFQ7 Cluster: Putative uncharacterized protein; n=1; ... 54 4e-06
UniRef50_A4R217 Cluster: Putative uncharacterized protein; n=1; ... 54 4e-06
UniRef50_Q03I00 Cluster: Aryl-alcohol dehydrogenase related enzy... 54 5e-06
UniRef50_Q6NKP1 Cluster: At5g53580; n=18; cellular organisms|Rep... 54 5e-06
UniRef50_P0A9T5 Cluster: Protein tas; n=88; Bacteria|Rep: Protei... 54 5e-06
UniRef50_UPI0001556575 Cluster: PREDICTED: similar to Aldo-keto ... 53 6e-06
UniRef50_Q98IA6 Cluster: Aryl-alcohol dehydrogenase; n=1; Mesorh... 53 6e-06
UniRef50_Q0RGM0 Cluster: Putative aldoketoreductase; n=2; Franki... 53 6e-06
UniRef50_A6W292 Cluster: Aldo/keto reductase; n=9; Bacteria|Rep:... 53 6e-06
UniRef50_Q9F3N3 Cluster: Putative oxidoreductase; n=3; Actinomyc... 53 8e-06
UniRef50_Q4Q5X1 Cluster: Aldehyde reductase, putative; n=75; cel... 53 8e-06
UniRef50_Q1FGT0 Cluster: Aldo/keto reductase; n=1; Clostridium p... 52 1e-05
UniRef50_A6VSN1 Cluster: Aldo/keto reductase; n=8; Proteobacteri... 52 1e-05
UniRef50_A6SUJ2 Cluster: Uncharacterized conserved protein; n=2;... 52 1e-05
UniRef50_Q40648 Cluster: Probable voltage-gated potassium channe... 52 1e-05
UniRef50_Q7NCE7 Cluster: Glr3032 protein; n=5; Cyanobacteria|Rep... 52 1e-05
UniRef50_A3I0G0 Cluster: Oxidoreductase; n=1; Algoriphagus sp. P... 52 1e-05
UniRef50_P54569 Cluster: Uncharacterized oxidoreductase yqkF; n=... 52 1e-05
UniRef50_Q5KYH6 Cluster: K+ channel beta subunit; n=5; Bacteria|... 52 2e-05
UniRef50_Q3ZWR6 Cluster: Oxidoreductase, aldo reductase; n=3; De... 52 2e-05
UniRef50_Q0FFB1 Cluster: Aldo/keto reductase; n=1; alpha proteob... 52 2e-05
UniRef50_A6CMV7 Cluster: Putative uncharacterized protein; n=2; ... 52 2e-05
UniRef50_A1ZPI5 Cluster: Oxidoreductase; n=1; Microscilla marina... 52 2e-05
UniRef50_A1SJZ0 Cluster: Aldo/keto reductase; n=11; Actinomyceta... 52 2e-05
UniRef50_A7PNT1 Cluster: Chromosome chr8 scaffold_23, whole geno... 52 2e-05
UniRef50_Q2UCK9 Cluster: Predicted oxidoreductases; n=16; Pezizo... 52 2e-05
UniRef50_O43488 Cluster: Aflatoxin B1 aldehyde reductase member ... 52 2e-05
UniRef50_A1SCW7 Cluster: Aldo/keto reductase; n=2; Actinomycetal... 51 3e-05
UniRef50_P49261 Cluster: Rho beta-crystallin; n=1; Lepidodactylu... 51 3e-05
UniRef50_A6EEC4 Cluster: Putative Norsolorinic acid reductase; n... 51 3e-05
UniRef50_A3IX63 Cluster: Putative oxidoreductase; n=1; Cyanothec... 51 3e-05
UniRef50_Q87SA8 Cluster: Oxidoreductase Tas, aldo/keto reductase... 50 5e-05
UniRef50_Q38Z15 Cluster: Putative aldo/keto reductase; n=2; Bact... 50 5e-05
UniRef50_A6S357 Cluster: Putative uncharacterized protein; n=2; ... 50 5e-05
UniRef50_Q8EVP7 Cluster: Putative oxidoreductase; n=3; Bacteria|... 50 6e-05
UniRef50_A7HL79 Cluster: Aldo/keto reductase; n=1; Fervidobacter... 50 6e-05
UniRef50_A0UVR1 Cluster: Aldo/keto reductase; n=3; Bacteria|Rep:... 50 6e-05
UniRef50_A0K1H5 Cluster: Aldo/keto reductase; n=6; Actinomycetal... 50 6e-05
UniRef50_Q00T51 Cluster: Aldo/keto reductase; n=2; Ostreococcus|... 50 6e-05
UniRef50_Q55FL2 Cluster: Putative uncharacterized protein; n=1; ... 50 6e-05
UniRef50_A6R5B4 Cluster: NAD(P)H-dependent D-xylose reductase; n... 50 6e-05
UniRef50_Q1EZH4 Cluster: Aldo/keto reductase:4Fe-4S ferredoxin, ... 50 8e-05
UniRef50_Q0AL14 Cluster: Aldo/keto reductase; n=1; Maricaulis ma... 50 8e-05
UniRef50_A7B2Y7 Cluster: Putative uncharacterized protein; n=1; ... 50 8e-05
UniRef50_Q97UJ7 Cluster: Oxidoreductase; n=4; Archaea|Rep: Oxido... 50 8e-05
UniRef50_Q97UG6 Cluster: Oxidoreductase; n=5; Archaea|Rep: Oxido... 50 8e-05
UniRef50_A3H9H5 Cluster: Aldo/keto reductase; n=2; Archaea|Rep: ... 50 8e-05
UniRef50_A1S0T5 Cluster: Aldo/keto reductase; n=2; Thermoprotei|... 50 8e-05
UniRef50_Q983C8 Cluster: Oxido-reductase, and dehydratase; MocA;... 49 1e-04
UniRef50_Q7UL88 Cluster: DTDP-4-keto-L-6-deoxy-hexose 2,3-reduct... 49 1e-04
UniRef50_Q7NJD8 Cluster: Gll1894 protein; n=5; Bacteria|Rep: Gll... 49 1e-04
UniRef50_Q04TM6 Cluster: Aryl-alcohol dehydrogenase-related oxid... 49 1e-04
UniRef50_A7HAM2 Cluster: Aldo/keto reductase; n=9; cellular orga... 49 1e-04
UniRef50_A5UXT4 Cluster: Aldo/keto reductase; n=2; Roseiflexus|R... 49 1e-04
UniRef50_A6RYK4 Cluster: Putative uncharacterized protein; n=1; ... 49 1e-04
UniRef50_Q7D3N9 Cluster: AGR_pAT_274p; n=3; Proteobacteria|Rep: ... 49 1e-04
UniRef50_Q45RB1 Cluster: Possible oxidoreductase; n=3; Actinomyc... 49 1e-04
UniRef50_Q0LP88 Cluster: Aldo/keto reductase; n=4; Bacteria|Rep:... 49 1e-04
UniRef50_A6C9W8 Cluster: Aldo/keto reductase; n=2; Planctomyceta... 49 1e-04
UniRef50_A4XIJ0 Cluster: Aldo/keto reductase; n=1; Caldicellulos... 49 1e-04
UniRef50_A1SLH1 Cluster: Aldo/keto reductase; n=27; Bacteria|Rep... 49 1e-04
UniRef50_Q5ASJ7 Cluster: Putative uncharacterized protein; n=1; ... 49 1e-04
UniRef50_A1DD54 Cluster: Aldo/keto reductase; n=3; Trichocomacea... 49 1e-04
UniRef50_UPI00005100E5 Cluster: COG0667: Predicted oxidoreductas... 48 2e-04
UniRef50_Q4J031 Cluster: Aldo/keto reductase precursor; n=2; Pse... 48 2e-04
UniRef50_A1RAH7 Cluster: Oxidoreductase, aldo/keto reductase fam... 48 2e-04
UniRef50_A0Y7Y8 Cluster: Aldo/keto reductase; n=1; marine gamma ... 48 2e-04
UniRef50_A0GDL6 Cluster: Aldo/keto reductase; n=1; Burkholderia ... 48 2e-04
UniRef50_P76187 Cluster: Oxidoreductase ydhF; n=51; Gammaproteob... 48 2e-04
UniRef50_Q98EU0 Cluster: Oxidoreductase; MocA; n=27; Bacteria|Re... 48 2e-04
UniRef50_Q1FGT1 Cluster: Aldo/keto reductase:4Fe-4S ferredoxin, ... 48 2e-04
UniRef50_A4QYA4 Cluster: Putative uncharacterized protein; n=1; ... 48 2e-04
UniRef50_Q6XUT6 Cluster: Oxido-reductase/dehydratase; n=3; Bacte... 48 3e-04
UniRef50_Q5V3K3 Cluster: Oxidoreductase aldo/keto reductase fami... 48 3e-04
UniRef50_Q46851 Cluster: Uncharacterized protein yghZ; n=126; Ba... 48 3e-04
UniRef50_Q88T82 Cluster: Oxidoreductase; n=18; Bacteria|Rep: Oxi... 47 4e-04
UniRef50_Q39MY8 Cluster: Aldo/keto reductase; n=10; Bacteria|Rep... 47 4e-04
UniRef50_A3TNI0 Cluster: Oxidoreductase, aldo/keto reductase fam... 47 4e-04
UniRef50_A1RJL6 Cluster: Aldo/keto reductase; n=37; Bacteria|Rep... 47 4e-04
UniRef50_A7RXR1 Cluster: Predicted protein; n=3; Eumetazoa|Rep: ... 47 4e-04
UniRef50_A1CCJ1 Cluster: Aldo/keto reductase; n=2; Trichocomacea... 47 4e-04
UniRef50_UPI0000611A01 Cluster: PREDICTED: similar to MGC80525 p... 47 6e-04
UniRef50_Q2J7H2 Cluster: Aldo/keto reductase; n=16; Bacteria|Rep... 47 6e-04
UniRef50_Q8VV02 Cluster: Putative oxidoreductase; n=1; Streptomy... 47 6e-04
UniRef50_A6VXX8 Cluster: Aldo/keto reductase; n=2; Marinomonas|R... 47 6e-04
UniRef50_A0JZE6 Cluster: Aldo/keto reductase; n=1; Arthrobacter ... 47 6e-04
UniRef50_A1CLD1 Cluster: Gamma-cysteine synthetase regulatory su... 47 6e-04
UniRef50_P42972 Cluster: Uncharacterized oxidoreductase ycsN; n=... 47 6e-04
UniRef50_UPI00003C85A8 Cluster: hypothetical protein Faci_030001... 46 7e-04
UniRef50_UPI000023DA24 Cluster: hypothetical protein FG10036.1; ... 46 7e-04
UniRef50_Q8Y5Q1 Cluster: Lmo2005 protein; n=34; cellular organis... 46 7e-04
UniRef50_Q27ST7 Cluster: Oxidoreductase; n=2; Eukaryota|Rep: Oxi... 46 7e-04
UniRef50_Q1IYI7 Cluster: Aldo/keto reductase; n=3; Deinococcus g... 46 0.001
UniRef50_Q099T4 Cluster: Oxidoreductase; n=2; Proteobacteria|Rep... 46 0.001
UniRef50_A6DNQ2 Cluster: YqkF; n=1; Lentisphaera araneosa HTCC21... 46 0.001
UniRef50_A0QHX8 Cluster: General stress protein 69; n=2; Mycobac... 46 0.001
UniRef50_P40691 Cluster: Auxin-induced protein PCNT115; n=65; ce... 46 0.001
UniRef50_Q13GB1 Cluster: Aldo/keto reductase; n=1; Burkholderia ... 46 0.001
UniRef50_A0K0K8 Cluster: Aryl-alcohol dehydrogenase (NADP(+)); n... 46 0.001
UniRef50_A7E982 Cluster: Putative uncharacterized protein; n=1; ... 46 0.001
UniRef50_Q8TTK4 Cluster: Aldo/keto reductase; n=28; cellular org... 46 0.001
UniRef50_P77256 Cluster: Uncharacterized oxidoreductase ydjG; n=... 46 0.001
UniRef50_Q1NH47 Cluster: Rhizopine catabolism protein; n=7; Prot... 45 0.002
UniRef50_A6VXU3 Cluster: Aldo/keto reductase; n=14; Proteobacter... 45 0.002
UniRef50_A5CYR4 Cluster: Predicted oxidoreductases; n=2; Clostri... 45 0.002
UniRef50_A3EV07 Cluster: Putative oxidoreductase; n=1; Leptospir... 45 0.002
UniRef50_Q6Q875 Cluster: SirO; n=1; Leptosphaeria maculans|Rep: ... 45 0.002
UniRef50_Q8EZ83 Cluster: Aldo/keto reductase family protein; n=1... 45 0.002
>UniRef50_Q8WRT0 Cluster: 3-dehydrecdysone 3b-reductase; n=1;
Trichoplusia ni|Rep: 3-dehydrecdysone 3b-reductase -
Trichoplusia ni (Cabbage looper)
Length = 308
Score = 263 bits (645), Expect = 3e-69
Identities = 133/214 (62%), Positives = 159/214 (74%), Gaps = 1/214 (0%)
Frame = +2
Query: 92 QAPCIQLHAGXPLPXVALGT-GRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEE 268
+AP QL+ G +P +ALGT G G I VRQAV WAI+AGYRHIDTAA+Y +EE
Sbjct: 23 KAPLKQLNDGNAIPSLALGTFGFG------DIPKVRQAVLWAIQAGYRHIDTAALYGNEE 76
Query: 269 QVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFP 448
+VG+GIA+AI GLV REELFVTTKLWNDKH R QVVPAL+ESL KLGL Y+DLYLIH P
Sbjct: 77 EVGKGIADAIQQGLVKREELFVTTKLWNDKHGRHQVVPALRESLTKLGLSYVDLYLIHSP 136
Query: 449 IATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIE 628
AT + P +ID L TW GM++A++LGLA+SIGVSNF+ + RL++ S P +NQIE
Sbjct: 137 EATNENGDPVDIDVLNTWNGMEEAKKLGLAKSIGVSNFDTALLDRLIAGSNTVPAVNQIE 196
Query: 629 VNPTNTQEPLXAHCXSLGIAVMAYSPFGFVVSRG 730
V+P+ TQE L A GI VMAYSPFGF VSRG
Sbjct: 197 VHPSKTQEKLVADSHERGIEVMAYSPFGFYVSRG 230
>UniRef50_Q9Y020 Cluster: 3-dehydroecdysone 3beta-reductase
precursor; n=1; Spodoptera littoralis|Rep:
3-dehydroecdysone 3beta-reductase precursor - Spodoptera
littoralis (Egyptian cotton leafworm)
Length = 345
Score = 197 bits (481), Expect = 2e-49
Identities = 96/216 (44%), Positives = 134/216 (62%), Gaps = 3/216 (1%)
Frame = +2
Query: 89 VQAPCIQLHAGXPLPXVALGTGRGTAKX---SDSIXXVRQAVYWAIEAGYRHIDTAAVYQ 259
+ P +++ +P +ALGT G K + +R V AI+ GYRH DTAA+Y
Sbjct: 20 IDVPMLKMLNDREMPAIALGTYLGFDKGGAVTSKDKQLRNVVMQAIDLGYRHFDTAAIYN 79
Query: 260 DEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLI 439
E +VG+ I I G++ RE++F+TTKLWN H R+QV A++E+L K GLDY+DL+L+
Sbjct: 80 TEAEVGEAIRMKIDEGVIKREDVFLTTKLWNTHHKREQVAVAMKETLNKTGLDYVDLFLM 139
Query: 440 HFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVIN 619
H+PIA D S N DYLETW+ ++ +LG +SIG+SNFN Q+ ++ I+PV
Sbjct: 140 HWPIALNEDYSHSNTDYLETWRATEEMVKLGYTKSIGLSNFNKLQVATVLQECTIKPVAL 199
Query: 620 QIEVNPTNTQEPLXAHCXSLGIAVMAYSPFGFVVSR 727
QIEV+P QE L + GI VM YSPFG +V R
Sbjct: 200 QIEVHPQIIQEDLITYAKDEGIIVMGYSPFGSLVKR 235
>UniRef50_UPI00015B56A2 Cluster: PREDICTED: similar to GA10458-PA;
n=2; Nasonia vitripennis|Rep: PREDICTED: similar to
GA10458-PA - Nasonia vitripennis
Length = 569
Score = 193 bits (470), Expect = 4e-48
Identities = 99/216 (45%), Positives = 140/216 (64%), Gaps = 11/216 (5%)
Frame = +2
Query: 98 PCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 277
P + + G +P + LGT +K + V +AV +AIE GYRH+DTA Y++E+++G
Sbjct: 4 PTVTFNDGYKMPMIGLGTF--LSKPGE----VAEAVKYAIEVGYRHVDTAFFYENEKEIG 57
Query: 278 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 457
I E I +G + RE++FVTTKLW + H D+VVPA ++SL+ LG DYIDL+L+H+P A
Sbjct: 58 SAIREKINDGTIKREDIFVTTKLWCNSHKEDEVVPACKKSLENLGFDYIDLFLVHWPFAF 117
Query: 458 K------PDDSPDNI-----DYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI 604
K P D+ I DYLETW+GM++ ++ GLARSIG+SNFN+ QI RL+S++ I
Sbjct: 118 KSGDALTPRDAAGKIEFSDTDYLETWKGMEECKRQGLARSIGLSNFNSEQIARLLSSAKI 177
Query: 605 RPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+PV NQ+EV Q+PL C I V +SP G
Sbjct: 178 KPVNNQVEVTMNLNQKPLIEFCKKHEITVTGFSPLG 213
Score = 165 bits (400), Expect = 1e-39
Identities = 87/170 (51%), Positives = 110/170 (64%), Gaps = 8/170 (4%)
Frame = +2
Query: 227 YRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKK 406
YRHIDTA +Y +E+ +G I E I +G V RE+LFVTTKL H +VVPA ++SL
Sbjct: 301 YRHIDTAYLYDNEKYIGNAIREKIKDGTVKREDLFVTTKLSYYAHKESEVVPACKQSLND 360
Query: 407 LGLDYIDLYLIHFPIA-----TKPDDSP---DNIDYLETWQGMQDARQLGLARSIGVSNF 562
LGLDYIDLYLIH+PI K + DYLETW+GM++ ++ GLARSIGVSNF
Sbjct: 361 LGLDYIDLYLIHWPIRRYFRHNKNASGKLLLSDTDYLETWKGMEECKRQGLARSIGVSNF 420
Query: 563 NATQITRLVSNSYIRPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
N+ QITRL+ + I+PV NQ+EV+ Q+ L C I V YSP G
Sbjct: 421 NSEQITRLLEAAKIKPVNNQVEVSLKLNQKALIEFCKKHDITVTGYSPLG 470
>UniRef50_UPI00015B56A3 Cluster: PREDICTED: similar to aldo-keto
reductase; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to aldo-keto reductase - Nasonia vitripennis
Length = 321
Score = 190 bits (463), Expect = 3e-47
Identities = 100/214 (46%), Positives = 137/214 (64%), Gaps = 11/214 (5%)
Frame = +2
Query: 104 IQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 283
I L G +P + LGT +G + V AV AI+AGYRH D A+ Y +E ++G+
Sbjct: 8 ITLSDGNKVPVLGLGTWQG----GNDPDEVENAVKLAIDAGYRHFDCASFYGNEAEIGKA 63
Query: 284 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFP----- 448
I E I G+V RE+LFV TK+WND+ ++ VV A + SLKKLGL YIDLYL+H+P
Sbjct: 64 IQEKIDQGVVKREDLFVVTKVWNDERKQELVVAACKRSLKKLGLGYIDLYLVHWPFSYPI 123
Query: 449 ------IATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRP 610
+ T + D +DY+ETW+GM++ +LGL RSIGVSNFN+ Q+TRL+ ++ I+P
Sbjct: 124 LYQYIVLPTYNAVTLDEVDYIETWRGMEECIKLGLTRSIGVSNFNSQQLTRLLESASIKP 183
Query: 611 VINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
V+NQIE++ Q+ L C S IAV YSPFG
Sbjct: 184 VMNQIELHINLNQKKLREFCASKSIAVTGYSPFG 217
>UniRef50_Q6TY50 Cluster: Reductase 2; n=10; Magnoliophyta|Rep:
Reductase 2 - Hydrangea macrophylla (Bigleaf hydrangea)
Length = 321
Score = 177 bits (431), Expect = 2e-43
Identities = 92/222 (41%), Positives = 142/222 (63%), Gaps = 10/222 (4%)
Frame = +2
Query: 83 MAVQAPCIQLHAGX-PLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQ 259
MA P + L +G +P + LGT ++ VR+AV A++ GYRH DTAA+Y
Sbjct: 1 MAFTIPEVPLSSGGRKMPVLGLGTAADPPVDPET---VRKAVTEALKLGYRHFDTAALYN 57
Query: 260 DEEQVGQGIAEAIANGLV-TREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYL 436
E+ +G IAEA+ GL+ +R+ELF+T+KLW R+ V PALQ++LK L L+YID+YL
Sbjct: 58 SEQPLGDAIAEALGEGLIKSRDELFITSKLWCSDAHRENVEPALQKTLKNLKLEYIDMYL 117
Query: 437 IHFPIATKPDD------SPD--NIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVS 592
IH+P+++KP + D +DY W+ M++ ++LGL ++IGVSNF+ +++ +++
Sbjct: 118 IHWPVSSKPGNYEYPIKKEDFLQMDYKSVWEAMEECQKLGLTKAIGVSNFSCKKLSDVLA 177
Query: 593 NSYIRPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFGFV 718
N+ + P +NQ+EVNP Q+ L C S GI V+AY+ G V
Sbjct: 178 NAKVPPAVNQVEVNPCWQQKQLTEFCKSNGILVVAYAALGAV 219
>UniRef50_Q7JVH6 Cluster: LD24696p; n=2; Sophophora|Rep: LD24696p -
Drosophila melanogaster (Fruit fly)
Length = 311
Score = 176 bits (428), Expect = 5e-43
Identities = 96/212 (45%), Positives = 131/212 (61%), Gaps = 8/212 (3%)
Frame = +2
Query: 95 APCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQV 274
AP I+L+ G +P + LGT + SD+ R A ++ GYRH+DTA VY++E +V
Sbjct: 5 APTIRLNNGREMPTLGLGTWKSFE--SDAYHSTRHA----LDVGYRHLDTAFVYENEAEV 58
Query: 275 GQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA 454
GQ I+E IA G+VTREE+FVTTKL H V A + SL LGL+Y+DLYL+H P+
Sbjct: 59 GQAISEKIAEGVVTREEVFVTTKLGGIHHDPALVERACRLSLSNLGLEYVDLYLMHMPVG 118
Query: 455 TK-PDDSP-------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRP 610
K +DS ++DYL+TW+ M+ LGL RSIG+SNFNA Q R+++N IRP
Sbjct: 119 QKFHNDSNVHGTLELTDVDYLDTWREMEKLVDLGLTRSIGLSNFNAAQTERVLANCRIRP 178
Query: 611 VINQIEVNPTNTQEPLXAHCXSLGIAVMAYSP 706
V+NQ+E +P Q L H G+ + AY P
Sbjct: 179 VVNQVECHPGFQQRQLREHAKRHGLVICAYCP 210
>UniRef50_P14550 Cluster: Alcohol dehydrogenase [NADP+]; n=44;
Bilateria|Rep: Alcohol dehydrogenase [NADP+] - Homo
sapiens (Human)
Length = 325
Score = 174 bits (423), Expect = 2e-42
Identities = 89/218 (40%), Positives = 132/218 (60%), Gaps = 12/218 (5%)
Frame = +2
Query: 95 APCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQV 274
A C+ LH G +P + LGT + V+ AV +A+ GYRHID AA+Y +E ++
Sbjct: 3 ASCVLLHTGQKMPLIGLGTWKSEP------GQVKAAVKYALSVGYRHIDCAAIYGNEPEI 56
Query: 275 GQGIAEAIANG-LVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPI 451
G+ + E + G V REELFVT+KLWN KH + V PAL+++L L L+Y+DLYL+H+P
Sbjct: 57 GEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPY 116
Query: 452 ATKPDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNS 598
A + D+P D+ Y ETW+ ++ GL +++G+SNFN+ QI ++S +
Sbjct: 117 AFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVA 176
Query: 599 YIRPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+RP + Q+E +P Q L AHC + G+ V AYSP G
Sbjct: 177 SVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLG 214
>UniRef50_Q01J82 Cluster: OSIGBa0152K17.5 protein; n=28;
Magnoliophyta|Rep: OSIGBa0152K17.5 protein - Oryza
sativa (Rice)
Length = 323
Score = 170 bits (413), Expect = 4e-41
Identities = 89/218 (40%), Positives = 132/218 (60%), Gaps = 9/218 (4%)
Frame = +2
Query: 86 AVQAPCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDE 265
AV ++ AG P+P V +GT A ++ R A A+E G+RH DTAA+Y E
Sbjct: 3 AVPEVALRHGAGRPMPAVGVGTADSAATSPET---KRGAALAALEVGFRHFDTAALYGTE 59
Query: 266 EQVGQGIAEAIANGLV-TREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIH 442
+G+ IAEA GLV +REE+FVTTKLW + V+P+L+ESL+ L ++Y+DLYL+H
Sbjct: 60 APLGEAIAEATRRGLVASREEVFVTTKLWCTQCHPGLVLPSLRESLRNLQMEYVDLYLVH 119
Query: 443 FPIATKPD--------DSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNS 598
+PI+ KP + D+ W+ M++ +LGLA++IGVSNF + +L++ +
Sbjct: 120 WPISVKPGPPMLPVKREDAVPFDFEGVWRAMEECHRLGLAKAIGVSNFTTKHLDKLLAVA 179
Query: 599 YIRPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
I P +NQ+E+NP Q + +C + GI V AYSP G
Sbjct: 180 TIPPAVNQVEMNPVWQQRTVREYCAAKGIRVAAYSPLG 217
>UniRef50_Q2LZ66 Cluster: GA19341-PA; n=2; Endopterygota|Rep:
GA19341-PA - Drosophila pseudoobscura (Fruit fly)
Length = 315
Score = 169 bits (412), Expect = 5e-41
Identities = 97/220 (44%), Positives = 128/220 (58%), Gaps = 12/220 (5%)
Frame = +2
Query: 89 VQAPCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEE 268
+ P L +G +P V LGT R + V QAV AI+ GYRH D A +Y +E
Sbjct: 1 MSTPSFLLSSGRNMPMVGLGTWRSPPEV------VAQAVKDAIDIGYRHFDCAHIYGNEL 54
Query: 269 QVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFP 448
VG I E I GLVTR+ELF+T+KLWN H + V A + SL+ LG+DY+DLYL+H+P
Sbjct: 55 HVGVAIREKIQEGLVTRDELFITSKLWNTFHKPELVRAACETSLRNLGIDYLDLYLMHWP 114
Query: 449 IATKPDDS-----PD-------NIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVS 592
+A K D+ PD +IDYL+TW+ M+D GL +IGVSNFN QI RL+
Sbjct: 115 MAYKSGDNLYPTCPDTGKAVFEDIDYLDTWKAMEDLVDSGLVNAIGVSNFNEKQINRLLC 174
Query: 593 NSYIRPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+ ++PV+ QIE +P Q+ L C I V AYS G
Sbjct: 175 LAKLKPVMLQIECHPYLRQKSLITLCYDNAIGVTAYSSLG 214
>UniRef50_A7SIT3 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 323
Score = 169 bits (411), Expect = 6e-41
Identities = 93/221 (42%), Positives = 129/221 (58%), Gaps = 11/221 (4%)
Frame = +2
Query: 83 MAVQAPCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQD 262
MA++ +L+ G +P +ALGT + + + V AV AIE GYRHID A +Y +
Sbjct: 1 MAMKQIFCKLNTGASIPAMALGTWQSSKEE------VGNAVRLAIELGYRHIDCAEIYGN 54
Query: 263 EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIH 442
E ++G+ ++E + G V REELFVT+KLW D H D V+PA Q +LK L LDY+DLYLIH
Sbjct: 55 EGEIGEALSEVLTEGKVKREELFVTSKLWCDSHHPDDVLPACQATLKNLQLDYLDLYLIH 114
Query: 443 FPIATK-----PDDSPDNI------DYLETWQGMQDARQLGLARSIGVSNFNATQITRLV 589
P+A K P + I TWQ M+ GL ++IGVSNF+ ++ +L+
Sbjct: 115 IPVAFKKGVRLPHSIAEGIIGYTPEGVQNTWQAMEGLVAKGLCKAIGVSNFSVKRLNKLL 174
Query: 590 SNSYIRPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+ I P NQ+E++P QE L C S GI + AYSP G
Sbjct: 175 ETASIVPACNQVELHPYLPQEKLKEFCDSKGILLTAYSPLG 215
>UniRef50_Q01HB5 Cluster: OSIGBa0136O08-OSIGBa0153H12.9 protein;
n=4; Oryza sativa|Rep: OSIGBa0136O08-OSIGBa0153H12.9
protein - Oryza sativa (Rice)
Length = 337
Score = 169 bits (410), Expect = 8e-41
Identities = 96/226 (42%), Positives = 134/226 (59%), Gaps = 14/226 (6%)
Frame = +2
Query: 77 AAMAVQAPCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVY 256
AA A PC+ L++G +P + GTG T + + A+ GYRH+DTAAVY
Sbjct: 14 AAAATAVPCVTLNSGHAMPVLGFGTGSSTPPAD-----LAATIAHAVRLGYRHLDTAAVY 68
Query: 257 QDEEQVGQGIAEAIANGLV-TREELFVTTKL-WNDKHARDQVVPALQESLKKLGLDYIDL 430
E VG +AEA+ G V +R ELFVTTKL D H +VV AL+ESL +LGLDY+DL
Sbjct: 69 GTEGAVGAAVAEAVRCGAVASRGELFVTTKLSMADAHP-PRVVAALRESLSRLGLDYVDL 127
Query: 431 YLIHFPIATKPDDSPDNI------------DYLETWQGMQDARQLGLARSIGVSNFNATQ 574
+LIH+P+A D+ + D W+GM++ +LGLARSIGVSNF+A +
Sbjct: 128 FLIHWPVAIGKKDAAGELTWDDLSRGLVPFDMEGVWRGMEECHRLGLARSIGVSNFSAAK 187
Query: 575 ITRLVSNSYIRPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
++RL++ + + P +NQ+E+N QE + C G+ V AYSP G
Sbjct: 188 MSRLLALAAVPPAVNQVEMNVGWRQEKVREVCGEGGVVVAAYSPLG 233
>UniRef50_A3C1Z7 Cluster: Putative uncharacterized protein; n=2;
Oryza sativa (japonica cultivar-group)|Rep: Putative
uncharacterized protein - Oryza sativa subsp. japonica
(Rice)
Length = 288
Score = 168 bits (409), Expect = 1e-40
Identities = 87/216 (40%), Positives = 132/216 (61%), Gaps = 11/216 (5%)
Frame = +2
Query: 98 PCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 277
P L +G P+P V +GT +D V+ V AIEAGYRH DTAAVYQ E +G
Sbjct: 2 PEAALSSGKPMPRVGMGTASFPLGATDP-STVKDVVLRAIEAGYRHFDTAAVYQTEAILG 60
Query: 278 QGIAEAIANGLV-TREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA 454
+AEA+ GLV +R+EL++T+KLW V+P+L+ +L+K+ ++Y+DLYLIHFP++
Sbjct: 61 DAVAEAVRAGLVASRDELYITSKLWVAHAHPGHVLPSLRRALRKMQMEYLDLYLIHFPVS 120
Query: 455 TKPDDSPDNIDYLE----------TWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI 604
+ + P+++ Y + W+ M++ ++LGL ++IGVSNF+ ++ L+S + I
Sbjct: 121 MRLAEDPESMTYSKDDLVMMDMEGVWKEMEECQRLGLTKAIGVSNFSCKKLETLLSFATI 180
Query: 605 RPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
P NQ+EV+P Q L C GI + AYSP G
Sbjct: 181 SPAANQVEVHPYCRQNKLREFCKEKGIQLCAYSPLG 216
>UniRef50_Q0IBY6 Cluster: Alcohol dehydrogenase; n=2;
Chroococcales|Rep: Alcohol dehydrogenase - Synechococcus
sp. (strain CC9311)
Length = 336
Score = 166 bits (404), Expect = 4e-40
Identities = 86/211 (40%), Positives = 130/211 (61%), Gaps = 10/211 (4%)
Frame = +2
Query: 110 LHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 289
L G +P + LGTG+ ++ V ++V AI+ GYRHID A++Y +EE+VG I
Sbjct: 24 LSNGDRMPLLGLGTGKSESRQ------VYKSVREAIKIGYRHIDCASIYGNEEEVGDAIR 77
Query: 290 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP-- 463
+AI N +TR EL++T+KLW++ H ++ V AL +SL+ LG+DY++LYLIH+P+ +P
Sbjct: 78 DAIQNHEITRSELWITSKLWSNCHGKNHVEAALSQSLQNLGVDYLNLYLIHWPVGIRPEK 137
Query: 464 ------DD--SPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVIN 619
DD +P+ ETW+ M+ R GL + IGVSNF ++ +LVS+ +P +N
Sbjct: 138 TFAESVDDLLTPEESPISETWEAMESTRDKGLTKHIGVSNFTVKKLQQLVSHCKQKPEVN 197
Query: 620 QIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
Q+E +P Q L +C S I + AYSP G
Sbjct: 198 QVEHHPLLQQPTLIEYCASEEILITAYSPLG 228
>UniRef50_Q9VTL0 Cluster: CG6083-PA; n=4; Diptera|Rep: CG6083-PA -
Drosophila melanogaster (Fruit fly)
Length = 322
Score = 166 bits (404), Expect = 4e-40
Identities = 92/221 (41%), Positives = 133/221 (60%), Gaps = 13/221 (5%)
Frame = +2
Query: 89 VQAPCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEE 268
+ P L G +P + LGT R + V QAV AI+ GYRH D A +Y +E
Sbjct: 1 MSTPNFLLSNGKNMPMLGLGTWRSPPEV------VTQAVKDAIDIGYRHFDCAHIYGNEA 54
Query: 269 QVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFP 448
QVG + E + G+VTR+ELF+T+KLWN H D V PA + S++ LG+ Y++LYL+H+P
Sbjct: 55 QVGAALREKMDEGVVTRDELFITSKLWNTHHKPDLVRPACETSIRNLGVKYLNLYLMHWP 114
Query: 449 IATK----------PDDSP---DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLV 589
+A K PD + ++IDY++TW+ M++ GL ++IGVSNFN Q+ RL+
Sbjct: 115 MAYKSGSDNLYPTCPDTNKAAFEDIDYVDTWRAMENLVDEGLCQAIGVSNFNEQQMNRLL 174
Query: 590 SNSYIRPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
S + ++PV+ QIE +P +Q+PL C IAV AYS G
Sbjct: 175 SVAKLKPVVLQIECHPYLSQKPLITLCYDNAIAVTAYSCLG 215
>UniRef50_Q7PCV3 Cluster: ENSANGP00000031808; n=9;
Endopterygota|Rep: ENSANGP00000031808 - Anopheles
gambiae str. PEST
Length = 316
Score = 166 bits (403), Expect = 6e-40
Identities = 89/186 (47%), Positives = 114/186 (61%), Gaps = 12/186 (6%)
Frame = +2
Query: 191 VRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARD 370
V QAV AI+ GYRHID A VYQ+E +VG+GIA IA G+V RE+LFVT+KLWN H D
Sbjct: 32 VAQAVKDAIDVGYRHIDCAHVYQNEHEVGEGIAAKIAEGVVKREDLFVTSKLWNTFHRPD 91
Query: 371 QVVPALQESLKKLGLDYIDLYLIHFPIATK---------PDDSP---DNIDYLETWQGMQ 514
V A + +L+ L LDY+DLYLIH+P+ + PD + DY++TW M+
Sbjct: 92 LVEGACKTTLQNLKLDYLDLYLIHWPVGYQEGTELFPMGPDGKTFLFSDADYVDTWPEME 151
Query: 515 DARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEPLXAHCXSLGIAVM 694
GL R+IGVSNFNA Q+ R++ + I P NQIE +P Q + C GI V
Sbjct: 152 KLVDAGLVRNIGVSNFNAKQVQRVLDVARIPPATNQIECHPYLHQSKITTFCAEKGIIVT 211
Query: 695 AYSPFG 712
AYSP G
Sbjct: 212 AYSPLG 217
>UniRef50_Q17DN0 Cluster: Aldo-keto reductase; n=5; Culicidae|Rep:
Aldo-keto reductase - Aedes aegypti (Yellowfever
mosquito)
Length = 324
Score = 165 bits (400), Expect = 1e-39
Identities = 92/220 (41%), Positives = 129/220 (58%), Gaps = 15/220 (6%)
Frame = +2
Query: 98 PCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 277
P ++L+ G +P + LGT +K + +AV AI+ G+RHIDTA Y++E+ VG
Sbjct: 7 PTVKLNNGLEMPAIGLGTSM--SKGDECC----KAVMTAIDEGFRHIDTAYNYRNEDVVG 60
Query: 278 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 457
+ I I G+VTREELFVTTKLWN H D V A +SL+ LGLDY+DL+LIH P
Sbjct: 61 RAIRAKIEEGVVTREELFVTTKLWNTFHHPDHVPMAFGKSLEHLGLDYVDLFLIHMPFGY 120
Query: 458 K----------PDDSPDNI-----DYLETWQGMQDARQLGLARSIGVSNFNATQITRLVS 592
+ P D N+ DY++TW+ M+ + G SIGVSNFN+ Q+ R+++
Sbjct: 121 EFNGWDPEKRTPLDDNGNVLCSDDDYVDTWKAMEKLLESGRVHSIGVSNFNSEQLERILA 180
Query: 593 NSYIRPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
N ++PV NQ+E + Q+ L C I V A+SPFG
Sbjct: 181 NCRVKPVTNQVECSARINQKLLIEFCMERDIVVTAHSPFG 220
>UniRef50_Q41399 Cluster: Chalcone reductase; n=4;
eudicotyledons|Rep: Chalcone reductase - Sesbania
rostrata
Length = 322
Score = 163 bits (397), Expect = 3e-39
Identities = 83/215 (38%), Positives = 137/215 (63%), Gaps = 10/215 (4%)
Frame = +2
Query: 98 PCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 277
P + L++G +P + +GT + +D + + AI+ GYRH D+A+VY EE +G
Sbjct: 7 PEVLLNSGHKMPVIGMGTSVESRPSNDVLASI---FVDAIQVGYRHFDSASVYGTEEAIG 63
Query: 278 QGIAEAIANGLV-TREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA 454
+++AI GL+ +R+E+F+T+K WN D +VPAL+ +LKKLG++Y+DLYLIH+P+
Sbjct: 64 MAVSKAIEQGLIKSRDEVFITSKPWNTDAHHDLIVPALKTTLKKLGMEYVDLYLIHWPVR 123
Query: 455 TKPD-DSP------DNIDY-LE-TWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR 607
+ D ++P D + + +E TW+ M++ +LGLA+SIG+ N+ ++T+L+ + I
Sbjct: 124 LRHDLENPVIFSKEDLLPFDIEGTWKAMEECYRLGLAKSIGICNYGTKKLTKLLEIATIP 183
Query: 608 PVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
P +NQ+E+NP+ Q L C GI V A+SP G
Sbjct: 184 PAVNQVEMNPSWQQGNLREFCKQKGIHVSAWSPLG 218
>UniRef50_Q1YPE5 Cluster: Aldehyde reductase; n=7; Bacteria|Rep:
Aldehyde reductase - gamma proteobacterium HTCC2207
Length = 330
Score = 163 bits (396), Expect = 4e-39
Identities = 98/229 (42%), Positives = 132/229 (57%), Gaps = 20/229 (8%)
Frame = +2
Query: 86 AVQAPCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDE 265
A+Q P +++ + +P V LG + T DS QAVY AI+ GYRH+D+AA Y +E
Sbjct: 4 AIQVPGVKV-SSKSMPAVGLGLWKIT---QDSAA---QAVYEAIKVGYRHLDSAADYGNE 56
Query: 266 EQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHF 445
+QVG+GIA AIA GL +REEL++TTKLWN H + V A + S+ LGLDYIDLYL+HF
Sbjct: 57 QQVGEGIARAIAEGLCSREELWITTKLWNTYHRAEHVEAACRRSMDDLGLDYIDLYLVHF 116
Query: 446 PIATK--------------------PDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFN 565
PIA + P D + ETW M+ + GL R IGV N++
Sbjct: 117 PIALRYVDFNDRYPAEWIFDHSAEDPAMELDQVPLSETWGAMEQLVESGLVRQIGVCNYS 176
Query: 566 ATQITRLVSNSYIRPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
A + L+S + I+P + QIE +P TQE L S +AV A+SP G
Sbjct: 177 AVLLHDLMSYARIKPAMLQIESHPYLTQEALLRTARSYNMAVTAFSPLG 225
>UniRef50_A5KSS3 Cluster: Aldehyde reductase; n=1; candidate
division TM7 genomosp. GTL1|Rep: Aldehyde reductase -
candidate division TM7 genomosp. GTL1
Length = 299
Score = 163 bits (396), Expect = 4e-39
Identities = 83/178 (46%), Positives = 117/178 (65%), Gaps = 11/178 (6%)
Frame = +2
Query: 212 AIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQ 391
AI+AGYRHID A +Y +E++VG+GI I G+V RE+LFVT+KLWN HA+ V A +
Sbjct: 34 AIKAGYRHIDCAMIYGNEKEVGEGIRRTIDQGVVKREDLFVTSKLWNTDHAQVDVGVACR 93
Query: 392 ESLKKLGLDYIDLYLIHFPIATKPDDSPDNID-----------YLETWQGMQDARQLGLA 538
++L LGLDY+DLYLIH+ +A + D+ + +D ETWQ M++ + GL
Sbjct: 94 KTLNDLGLDYLDLYLIHWGVAFEHGDNLEPLDDDGVAKFSFISMKETWQAMEELVEQGLV 153
Query: 539 RSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+S+GV+NF A + L+S + I+P ++QIE++P Q L A C S IAV AYSPFG
Sbjct: 154 KSMGVANFTAPMLLDLLSYAKIKPAVHQIELHPYLAQNDLVAFCYSQNIAVTAYSPFG 211
>UniRef50_Q7G764 Cluster: Probable NAD(P)H-dependent oxidoreductase
1; n=32; Eukaryota|Rep: Probable NAD(P)H-dependent
oxidoreductase 1 - Oryza sativa subsp. japonica (Rice)
Length = 321
Score = 161 bits (392), Expect = 1e-38
Identities = 86/206 (41%), Positives = 128/206 (62%), Gaps = 11/206 (5%)
Frame = +2
Query: 128 LPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANG 307
+P V +GT S+ A+ AIE GYRH DTA +Y E VG+ +AEA+ G
Sbjct: 16 MPRVGMGTAAFPFTSSEDTTA---AMLRAIELGYRHFDTARIYATEGCVGEAVAEAVRRG 72
Query: 308 LV-TREELFVTTKLW-NDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPD--DSP 475
L+ +R ++FVT+K+W +D HA +VVPA +E+L+ LG+DY+DL L+H+P++ P D P
Sbjct: 73 LIASRADVFVTSKIWCSDLHA-GRVVPAARETLRNLGMDYVDLLLVHWPVSLTPGNYDFP 131
Query: 476 -------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVN 634
+ D W+GM++ +LGLAR+IGVSNF+A ++ +L+S + +RP +NQ+EVN
Sbjct: 132 FPKEVILPSFDMEGVWRGMEECHRLGLARAIGVSNFSAKKLEQLLSLAAVRPAVNQVEVN 191
Query: 635 PTNTQEPLXAHCXSLGIAVMAYSPFG 712
P Q L C G+ + YSP G
Sbjct: 192 PMWQQRTLREVCRREGVQLCGYSPLG 217
>UniRef50_A5E082 Cluster: GCY protein; n=4; Saccharomycetales|Rep:
GCY protein - Lodderomyces elongisporus (Yeast)
(Saccharomyces elongisporus)
Length = 295
Score = 161 bits (391), Expect = 2e-38
Identities = 90/219 (41%), Positives = 137/219 (62%), Gaps = 5/219 (2%)
Frame = +2
Query: 71 LHAAMAVQAPCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAA 250
+ + +++ L+ G +P + LGT +D +A A++ GY+HIDTAA
Sbjct: 1 MSSQLSINTKTYTLNNGLKIPAIGLGTW-----LADEEDAAYKATLTALKNGYKHIDTAA 55
Query: 251 VYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDL 430
Y +E+QVG+ AIA+ V+R+E+FVTTKLWND+H + AL ESLKKLGL+Y+DL
Sbjct: 56 AYGNEDQVGR----AIADSGVSRDEIFVTTKLWNDQHKDPE--GALDESLKKLGLEYVDL 109
Query: 431 YLIHFPIATKP-DDSP-DNIDYLETWQGMQDARQLG-LARSIGVSNFNATQITRLVSNSY 601
YLIH+P++ P + P D+ D+++TW+ +Q + G ++IGVSNFN ++ +L+++
Sbjct: 110 YLIHWPLSVDPKTEKPYDDYDFVDTWRNLQKIYKEGKKVKAIGVSNFNKKKLDKLLNSEG 169
Query: 602 IR--PVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+ PVINQIE +P TQ L + S I + AYSP G
Sbjct: 170 VNVVPVINQIEAHPLLTQPDLFDYLKSKDIYITAYSPLG 208
>UniRef50_P45376 Cluster: Aldose reductase; n=21; Bilateria|Rep:
Aldose reductase - Mus musculus (Mouse)
Length = 316
Score = 161 bits (391), Expect = 2e-38
Identities = 89/216 (41%), Positives = 127/216 (58%), Gaps = 13/216 (6%)
Frame = +2
Query: 104 IQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 283
++L+ G +P + LGT + V +AV AI+ GYRHID A VYQ+E++VG
Sbjct: 5 LELNNGTKMPTLGLGTWKSPP------GQVTEAVKVAIDLGYRHIDCAQVYQNEKEVGVA 58
Query: 284 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 463
+ E + +V R++LF+ +KLW H + V A Q++L L LDY+DLYLIH+P KP
Sbjct: 59 LQEKLKEQVVKRQDLFIVSKLWCTFHDKSMVKGAFQKTLSDLQLDYLDLYLIHWPTGFKP 118
Query: 464 -------DDS----PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI-- 604
D S P + D+++TW M+ GL ++IGVSNFN QI R+++ +
Sbjct: 119 GPDYFPLDASGNVIPSDTDFVDTWTAMEQLVDEGLVKTIGVSNFNPLQIERILNKPGLKY 178
Query: 605 RPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+P +NQIE +P TQE L +C S GI V AYSP G
Sbjct: 179 KPAVNQIECHPYLTQEKLIEYCHSKGIVVTAYSPLG 214
>UniRef50_Q8VC28 Cluster: Aldo-keto reductase family 1 member C13;
n=11; Theria|Rep: Aldo-keto reductase family 1 member
C13 - Mus musculus (Mouse)
Length = 323
Score = 160 bits (389), Expect = 3e-38
Identities = 85/224 (37%), Positives = 132/224 (58%), Gaps = 14/224 (6%)
Frame = +2
Query: 83 MAVQAPCIQLHAGXPLPXVALGTGRGT-AKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQ 259
M+ + C++L+ G +P + GT + S S+ +A A++ GYRH+DTA YQ
Sbjct: 1 MSSKQHCVKLNDGHLIPALGFGTYKPKEVPKSKSL----EAACLALDVGYRHVDTAYAYQ 56
Query: 260 DEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLI 439
EE++GQ I I G+V RE+LF+TTKLW + V PAL++SLKKL LDY+DLY++
Sbjct: 57 VEEEIGQAIQSKIKAGVVKREDLFITTKLWCTCFRPELVKPALEKSLKKLQLDYVDLYIM 116
Query: 440 HFPIATKPDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRL 586
H+P+ K D+ D +D+ +TW+ +++ + GL +SIGVSNFN Q+ R+
Sbjct: 117 HYPVPMKSGDNDFPVNEQGKSLLDTVDFCDTWERLEECKDAGLVKSIGVSNFNHRQLERI 176
Query: 587 VSNSYI--RPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
++ + +PV NQ+E + Q L +C S I ++AY G
Sbjct: 177 LNKPGLKYKPVCNQVECHLYLNQRKLLDYCESKDIVLVAYGALG 220
>UniRef50_Q7QK25 Cluster: ENSANGP00000019775; n=2; Anopheles gambiae
str. PEST|Rep: ENSANGP00000019775 - Anopheles gambiae
str. PEST
Length = 319
Score = 160 bits (388), Expect = 4e-38
Identities = 89/226 (39%), Positives = 128/226 (56%), Gaps = 16/226 (7%)
Frame = +2
Query: 83 MAVQAPCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQD 262
M+ Q P ++ G +P LG G A+ + V++A I+ GYRHIDTA +Y++
Sbjct: 1 MSTQVPTVRFSNGYEIP--VLGYGTYLAQKGQCVELVKKA----IDLGYRHIDTAFLYEN 54
Query: 263 EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIH 442
E ++GQ I + IA G++ RE++FVTTKLWN H V A + S L + YIDL+L+H
Sbjct: 55 EVEIGQAIRDKIAEGVIRREDVFVTTKLWNTFHDPQHVEEAFRRSFDMLDIGYIDLFLMH 114
Query: 443 FPIAT----------KPDDSPDN-----IDYLETWQGMQD-ARQLGLARSIGVSNFNATQ 574
P+ +P D+ N +DY+ETW+ M+ G RSIG+SNFN+ Q
Sbjct: 115 SPMGVQFSGYEYADMQPKDAAGNMLFSDVDYVETWKAMEKLVTAGGRVRSIGLSNFNSEQ 174
Query: 575 ITRLVSNSYIRPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
I R++ + ++PV NQ+E NP Q L A C + GI V AY P G
Sbjct: 175 IERILQIATVKPVNNQVEANPGYDQRKLIAFCQARGITVTAYGPMG 220
>UniRef50_P26690 Cluster: NAD(P)H-dependent 6'-deoxychalcone
synthase; n=3; Papilionoideae|Rep: NAD(P)H-dependent
6'-deoxychalcone synthase - Glycine max (Soybean)
Length = 315
Score = 159 bits (385), Expect = 9e-38
Identities = 82/201 (40%), Positives = 127/201 (63%), Gaps = 8/201 (3%)
Frame = +2
Query: 152 GRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELF 331
G G+A ++A+ A++ GYRH DTAA Y E+ +G+ + EAI GLV+R++LF
Sbjct: 25 GMGSAPDFTCKKDTKEAIIEAVKQGYRHFDTAAAYGSEQALGEALKEAIHLGLVSRQDLF 84
Query: 332 VTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPD--DSPDNI------D 487
VT+KLW ++ V+PAL++SLK L L+Y+DLYLIH+P++++P P + D
Sbjct: 85 VTSKLWVTENHPHLVLPALRKSLKTLQLEYLDLYLIHWPLSSQPGKFSFPIEVEDLLPFD 144
Query: 488 YLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEPLXAH 667
W+ M++ ++LGL ++IGVSNF+ ++ L+S + IRPV++Q+E+N Q+ L
Sbjct: 145 VKGVWESMEECQKLGLTKAIGVSNFSVKKLQNLLSVATIRPVVDQVEMNLAWQQKKLREF 204
Query: 668 CXSLGIAVMAYSPFGFVVSRG 730
C GI V A+SP SRG
Sbjct: 205 CKENGIIVTAFSPLRKGASRG 225
>UniRef50_Q8CI22 Cluster: 2310005E10Rik protein; n=30;
Tetrapoda|Rep: 2310005E10Rik protein - Mus musculus
(Mouse)
Length = 316
Score = 158 bits (384), Expect = 1e-37
Identities = 91/219 (41%), Positives = 125/219 (57%), Gaps = 13/219 (5%)
Frame = +2
Query: 95 APCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQV 274
A + L G +P V LGT + VR+AV AI+AGYRHID A VYQ+E +V
Sbjct: 2 AAFVTLLTGAKMPIVGLGTWKSPP------AKVREAVKVAIDAGYRHIDCAYVYQNESEV 55
Query: 275 GQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA 454
G+ I E I V RE+LF+ +KLW+ + V A Q +L L LDY+DLYLIH+P
Sbjct: 56 GEAIQEKIQEKAVKREDLFIVSKLWSTFFEKSLVKKAFQNTLSDLKLDYLDLYLIHWPQG 115
Query: 455 TK------PDDSPDNI-----DYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSY 601
+ P D +I +L+ W+ M++ GL +++GVSNFN QI RL++
Sbjct: 116 FQSGNVFLPTDDKGSILSSKYTFLDAWEAMEELVDQGLVKALGVSNFNHFQIERLLNKPG 175
Query: 602 I--RPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+ +PV NQ+E +P TQE L +C S GI + AYSP G
Sbjct: 176 LKHKPVTNQVECHPYLTQEKLTQYCHSKGITITAYSPLG 214
>UniRef50_A3U9Y0 Cluster: Aldehyde reductase; n=5;
Bacteroidetes|Rep: Aldehyde reductase - Croceibacter
atlanticus HTCC2559
Length = 316
Score = 158 bits (383), Expect = 2e-37
Identities = 83/214 (38%), Positives = 130/214 (60%), Gaps = 11/214 (5%)
Frame = +2
Query: 104 IQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 283
++ G +P + LGT + + V++AV A+E GY+HID AA Y +E+ VG+
Sbjct: 4 LKFRDGDSIPSIGLGTWKSDPED------VKKAVKIALENGYKHIDCAAAYDNEDAVGEA 57
Query: 284 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 463
E+ +G V RE++FVT+KLWN+ H ++ V+PAL+++LK L LDY+DLYL+H+P+A KP
Sbjct: 58 FKESFESGNVKREDIFVTSKLWNNAHKKEDVIPALKKTLKDLNLDYLDLYLMHWPVAFKP 117
Query: 464 --DDSPD-NIDYL--------ETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRP 610
+ P+ + DYL ET M +A++ GL + +GVSNF+ ++ L P
Sbjct: 118 SVNGFPEKDEDYLSLEEAPLHETLNAMIEAKKQGLIKHVGVSNFSKEKLESLKGKVEEMP 177
Query: 611 VINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+NQ+E++P Q L ++C GI + YSP G
Sbjct: 178 EMNQVELHPYLPQNDLYSYCSKEGILLTGYSPLG 211
>UniRef50_P15121 Cluster: Aldose reductase; n=72; Eumetazoa|Rep:
Aldose reductase - Homo sapiens (Human)
Length = 316
Score = 157 bits (382), Expect = 2e-37
Identities = 89/214 (41%), Positives = 124/214 (57%), Gaps = 13/214 (6%)
Frame = +2
Query: 110 LHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 289
L+ G +P + LGT + V +AV AI+ GYRHID A VYQ+E +VG I
Sbjct: 7 LNNGAKMPILGLGTWKSPP------GQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQ 60
Query: 290 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP-- 463
E + +V REELF+ +KLW H + V A Q++L L LDY+DLYLIH+P KP
Sbjct: 61 EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK 120
Query: 464 -----DDS----PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI--RP 610
D+S P + + L+TW M++ GL ++IG+SNFN Q+ +++ + +P
Sbjct: 121 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP 180
Query: 611 VINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+NQIE +P TQE L +C S GI V AYSP G
Sbjct: 181 AVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLG 214
>UniRef50_Q03TW0 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=1; Lactobacillus brevis ATCC
367|Rep: Aldo/keto reductase of diketogulonate reductase
family - Lactobacillus brevis (strain ATCC 367 / JCM
1170)
Length = 293
Score = 156 bits (379), Expect = 5e-37
Identities = 83/205 (40%), Positives = 126/205 (61%)
Frame = +2
Query: 98 PCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 277
P + ++ G +P + LG + D+ + A+ WA+ AGYRHIDTAA Y +E+ VG
Sbjct: 12 PDLPMNNGHQIPQLGLGVFQ-----VDNAEDTKNAIKWALAAGYRHIDTAAYYGNEQWVG 66
Query: 278 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 457
+ I E+ V R+++FVT+KLWN D+ A QE+L KLGLDY+DLYLIH+P
Sbjct: 67 EAIRESD----VPRDQIFVTSKLWNSVRGYDETQAAFQETLDKLGLDYLDLYLIHWP--- 119
Query: 458 KPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNP 637
+P YL++W+ M+D + G ++IGVSNFN TQ+ ++++ ++PV++QIE +P
Sbjct: 120 ----AP---GYLDSWRAMEDLYKAGKIKNIGVSNFNQTQMADILAHGTVKPVVDQIETHP 172
Query: 638 TNTQEPLXAHCXSLGIAVMAYSPFG 712
Q + A+ S GI A+SP G
Sbjct: 173 YFQQNDMHAYLESQGILHEAWSPLG 197
>UniRef50_Q9FJK0 Cluster: Aldose reductase-like protein; n=3; core
eudicotyledons|Rep: Aldose reductase-like protein -
Arabidopsis thaliana (Mouse-ear cress)
Length = 316
Score = 154 bits (374), Expect = 2e-36
Identities = 83/211 (39%), Positives = 121/211 (57%), Gaps = 9/211 (4%)
Frame = +2
Query: 107 QLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGI 286
+L G +P + +GT +I V QA I+ GYRH DTA +Y EE +G +
Sbjct: 7 RLRCGETIPLLGMGTYCPQKDRESTISAVHQA----IKIGYRHFDTAKIYGSEEALGTAL 62
Query: 287 AEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP- 463
+AI+ G V R++LFVT+KLW+ H + AL ++LK +GLDY+D YL+H+PI KP
Sbjct: 63 GQAISYGTVQRDDLFVTSKLWSSDH--HDPISALIQTLKTMGLDYLDNYLVHWPIKLKPG 120
Query: 464 --------DDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVIN 619
D+ ++ ETWQGM+ ++GL RSIGVSNF++ +I L+ + + P +N
Sbjct: 121 VSEPIPKEDEFEKDLGIEETWQGMERCLEMGLCRSIGVSNFSSKKIFDLLDFASVSPSVN 180
Query: 620 QIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
Q+E++P Q L C I V YSP G
Sbjct: 181 QVEMHPLWRQRKLRKVCEENNIHVSGYSPLG 211
>UniRef50_Q4Q5N9 Cluster: Prostaglandin f synthase, putative; n=7;
cellular organisms|Rep: Prostaglandin f synthase,
putative - Leishmania major
Length = 279
Score = 154 bits (374), Expect = 2e-36
Identities = 82/210 (39%), Positives = 126/210 (60%)
Frame = +2
Query: 83 MAVQAPCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQD 262
MAV+ + L G +P + +GT AK + + ++ WA+ AGYRH+DTA Y++
Sbjct: 1 MAVKCTHVTLSNGVQVPQLGIGTWE--AKDGNEVVNIK----WAVNAGYRHVDTAHYYKN 54
Query: 263 EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIH 442
E+ VGQGI+E G V R ++FVTTKLWN H + + A ++S + LG++Y+DLYLIH
Sbjct: 55 EKGVGQGISEC---G-VPRSDIFVTTKLWNYDHGYESALAAFEQSRQALGVEYVDLYLIH 110
Query: 443 FPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQ 622
+P P N Y+ETW+ + ++ R+IGVSNF + L++N + P++NQ
Sbjct: 111 WP-------GP-NRSYIETWRAFEKLYEMKKVRAIGVSNFEPHHLDDLLANCTVPPMVNQ 162
Query: 623 IEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+E++P Q+ L A+C IAV A+ P G
Sbjct: 163 VEMHPHFQQKALRAYCAEKNIAVTAWRPLG 192
>UniRef50_A2QBD7 Cluster: Catalytic activity: an alcohol + NADP(+)
<=> an aldehyde + NADPH; n=4; Trichocomaceae|Rep:
Catalytic activity: an alcohol + NADP(+) <=> an aldehyde
+ NADPH - Aspergillus niger
Length = 323
Score = 154 bits (374), Expect = 2e-36
Identities = 90/212 (42%), Positives = 125/212 (58%), Gaps = 11/212 (5%)
Frame = +2
Query: 110 LHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 289
++ G +P V GT + AK + V AV A+ GYRHID AA+Y++E +VG GI
Sbjct: 9 INTGAKIPAVGFGTWQ--AKPLE----VENAVEVALREGYRHIDCAAIYRNETEVGNGIR 62
Query: 290 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDD 469
++ G V REE+F+T KLWN KHA + V PAL ++L+ LG+ Y+DLYL+H+P A K D
Sbjct: 63 KS---G-VPREEIFITGKLWNTKHAPEDVEPALDKTLQDLGVAYLDLYLMHWPCAFKGGD 118
Query: 470 -----SPD------NIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVI 616
+ D NIDY+ T++ M+ G R+IGVSNFN ++ L+ + P +
Sbjct: 119 KWFPLNDDGVFDLANIDYITTYRAMEKLLATGKVRAIGVSNFNIRRLEELLGQVSVVPAV 178
Query: 617 NQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
NQIE +P Q L C S GI + AYSP G
Sbjct: 179 NQIEAHPYLQQPDLLQFCQSKGILIEAYSPLG 210
>UniRef50_Q7G765 Cluster: Probable NAD(P)H-dependent oxidoreductase
2; n=6; Magnoliophyta|Rep: Probable NAD(P)H-dependent
oxidoreductase 2 - Oryza sativa subsp. japonica (Rice)
Length = 322
Score = 154 bits (374), Expect = 2e-36
Identities = 83/206 (40%), Positives = 123/206 (59%), Gaps = 11/206 (5%)
Frame = +2
Query: 128 LPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANG 307
+P + +GT S+ A+ AIE GYRH DTA +Y E V + +AEA+ G
Sbjct: 18 MPRIGMGTAAFPFTSSEETTA---ALLRAIELGYRHFDTARLYATEGCVSEAVAEAVRRG 74
Query: 308 LV-TREELFVTTKLW-NDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP------ 463
LV +R ++FVT+KLW +D HA +VVPA +E+L+ LG+DY+DL L+H+P P
Sbjct: 75 LVASRADVFVTSKLWCSDLHA-GRVVPAARETLRNLGMDYVDLLLVHWPATVAPGSYDFP 133
Query: 464 ---DDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVN 634
++ D W+GM++ +LGLAR+IGVSNF+A ++ +L+S + +RP NQ+E+N
Sbjct: 134 FPKEEMAPAFDMEGVWRGMEECHRLGLARAIGVSNFSAKKLEQLLSFAVVRPAANQVEMN 193
Query: 635 PTNTQEPLXAHCXSLGIAVMAYSPFG 712
P Q L C G+ + YSP G
Sbjct: 194 PMWQQRTLREVCRREGVQLCGYSPLG 219
>UniRef50_Q5BKE9 Cluster: LOC594893 protein; n=5; Xenopus
tropicalis|Rep: LOC594893 protein - Xenopus tropicalis
(Western clawed frog) (Silurana tropicalis)
Length = 345
Score = 153 bits (372), Expect = 3e-36
Identities = 86/207 (41%), Positives = 117/207 (56%), Gaps = 13/207 (6%)
Frame = +2
Query: 131 PXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGL 310
P GT GT K I VR A A++ GYRH+D A +Y E VGQ E A+G
Sbjct: 38 PGHCAGTKHGTEKSF--IDDVRVATKMALDLGYRHVDGAFLYSSETGVGQAFREKFADGT 95
Query: 311 VTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDS--P--- 475
+ RE+LF T+KLWN H V PAL+++L L +DY+DLYLIH P++ KP + P
Sbjct: 96 LKREDLFYTSKLWNTFHQPHLVRPALEKTLSFLQMDYVDLYLIHMPMSFKPAEELFPKNE 155
Query: 476 ------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI--RPVINQIEV 631
D D L+TWQ +++ R GL +SIGVSNFN Q+ +++ + +PV NQIE
Sbjct: 156 DGTCAFDQPDLLQTWQALEECRDAGLVKSIGVSNFNRRQLEMILNKPGLKYKPVCNQIEC 215
Query: 632 NPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+P Q+ + C S I V+AY G
Sbjct: 216 HPYLNQKQMLEFCKSKDIVVVAYGVLG 242
>UniRef50_Q4P4P1 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 322
Score = 153 bits (372), Expect = 3e-36
Identities = 81/201 (40%), Positives = 118/201 (58%)
Frame = +2
Query: 104 IQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 283
I+L+ G +P VALG + S A WA +AGYRHID+AA Y +EE VG+
Sbjct: 19 IKLNNGQEIPQVALGVYKAPNDGS-----TENACKWAFDAGYRHIDSAARYMNEESVGRA 73
Query: 284 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 463
+AE V R E+F+T+KLW+ H D+ A+++SLKKL +DY+D+YL+H P
Sbjct: 74 LAEWTKENNVPRSEIFITSKLWDADH--DKAAAAIEDSLKKLNVDYMDMYLMHSPGTMGA 131
Query: 464 DDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTN 643
+ LE W+ +++A G ++IGVSNF+ ++ L++N I+P +NQIE +P
Sbjct: 132 EKR------LEAWKALEEAVDAGKIKTIGVSNFDVEELDHLLANCRIKPAVNQIESHPFF 185
Query: 644 TQEPLXAHCXSLGIAVMAYSP 706
E L C S GI + AYSP
Sbjct: 186 AHEELREACISRGIHIQAYSP 206
>UniRef50_Q8K023 Cluster: Aldo-keto reductase family 1 member C18;
n=72; Tetrapoda|Rep: Aldo-keto reductase family 1 member
C18 - Mus musculus (Mouse)
Length = 323
Score = 153 bits (372), Expect = 3e-36
Identities = 82/216 (37%), Positives = 125/216 (57%), Gaps = 13/216 (6%)
Frame = +2
Query: 104 IQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 283
I+L+ G +P + GT A ++ AI+ G+ HID + +YQ+EE++GQ
Sbjct: 8 IELNDGHSIPVLGFGT---YATEEHLKKKSMESTKIAIDVGFCHIDCSHLYQNEEEIGQA 64
Query: 284 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 463
I I +G V RE++F T+KLW+ H + V P+L+ SL+KL LDY+DLYLIHFP++ KP
Sbjct: 65 ILSKIEDGTVKREDIFYTSKLWSTSHRPELVRPSLENSLRKLNLDYVDLYLIHFPVSLKP 124
Query: 464 DDS--P---------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI-- 604
+ P D +D +TW+ M+ + GLA+SIGVSNFN Q+ +++ +
Sbjct: 125 GNELLPKDEHGNLIFDTVDLCDTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKY 184
Query: 605 RPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+PV NQ+E + Q L A+C I ++AY G
Sbjct: 185 KPVCNQVECHLYLNQSKLLAYCKMNDIVLVAYGALG 220
>UniRef50_Q2S340 Cluster: Aldehyde reductase; n=10; Bacteria|Rep:
Aldehyde reductase - Salinibacter ruber (strain DSM
13855)
Length = 321
Score = 153 bits (371), Expect = 4e-36
Identities = 80/213 (37%), Positives = 125/213 (58%), Gaps = 10/213 (4%)
Frame = +2
Query: 104 IQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 283
I G +P + LGT + V +AV A+EAGYRH+D A +Y++E +VG
Sbjct: 4 ISFENGDEMPMIGLGTWKSPP------GEVYEAVTTALEAGYRHVDCAPIYKNETEVGAA 57
Query: 284 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK- 460
++++ G + R++++VT+KLWN+ H D V PAL+++L L LD +DLYLIH+P+A +
Sbjct: 58 LSDSFDAGGIRRDDVWVTSKLWNNAHHPDDVRPALEQTLSDLRLDALDLYLIHWPVALQP 117
Query: 461 -------PDD--SPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPV 613
PDD SP+ + ETW M+ ++ GL R IGVSNF+ + ++ +RP
Sbjct: 118 EVDFPESPDDFVSPEAVPLTETWAAMEALKKDGLVRHIGVSNFSVPNLQMILDAGEVRPE 177
Query: 614 INQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+NQ+E++P Q L + + I + AYSP G
Sbjct: 178 MNQVEMHPYLPQPELVSFAEAHNIPITAYSPLG 210
>UniRef50_Q54B70 Cluster: Aldehyde reductase; n=2; Dictyostelium
discoideum|Rep: Aldehyde reductase - Dictyostelium
discoideum AX4
Length = 297
Score = 153 bits (371), Expect = 4e-36
Identities = 82/214 (38%), Positives = 123/214 (57%), Gaps = 9/214 (4%)
Frame = +2
Query: 98 PCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 277
P +L +G +P V GT + V +AV A++AGYRHID AAVY +E++VG
Sbjct: 3 PSFKLSSGHKIPLVGFGTWKAET------TLVGKAVEVALDAGYRHIDCAAVYLNEKEVG 56
Query: 278 QGIAEAIAN-GLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA 454
+ + V RE++F+T+KLWN H ++ V PAL+ +L LGL Y+DLYL+H+P+A
Sbjct: 57 EAFTKKFTTEATVKREDVFITSKLWNTFHKKEHVRPALERTLSDLGLQYLDLYLVHWPVA 116
Query: 455 ---TKPD-----DSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRP 610
T D + + + ETW+ M+ GL +SIG+SNFN + ++S + I+P
Sbjct: 117 FEYTSNDIQTSGSTQEFVSIRETWEEMEKLVDAGLVKSIGLSNFNVQGLMEVLSYARIKP 176
Query: 611 VINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
NQ+E++P +Q L C I + AYSP G
Sbjct: 177 AANQVELHPFLSQPELKKFCDKHNIHLTAYSPLG 210
>UniRef50_Q16K66 Cluster: Aldo-keto reductase; n=2; Aedes
aegypti|Rep: Aldo-keto reductase - Aedes aegypti
(Yellowfever mosquito)
Length = 303
Score = 153 bits (371), Expect = 4e-36
Identities = 84/211 (39%), Positives = 125/211 (59%), Gaps = 8/211 (3%)
Frame = +2
Query: 104 IQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 283
+ L+ G +P + LGT + T SD + ++ AV E GYR IDTA VY +E+ VGQ
Sbjct: 2 LALNNGHSIPPIGLGTYKITG--SDGVAAIKSAV----EFGYRLIDTAFVYNNEQVVGQA 55
Query: 284 IAEAIANGL-VTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 460
+ E + G + RE++F+ +KL H + V + SL++LGLDY+DLYL+H P+A +
Sbjct: 56 LREIFSQGNDINREDVFIVSKLGPTFHRPEAVEKGCRLSLERLGLDYVDLYLMHTPVAAR 115
Query: 461 PD-------DSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVIN 619
+ D + LETW+ +++ ++ GL RSIGVSNFN Q+ +V++ IRPV+N
Sbjct: 116 DSGDGNDRSEIDDEVTPLETWKALEECQRKGLVRSIGVSNFNEEQLMEIVTHGSIRPVVN 175
Query: 620 QIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
Q+E + Q L C GI +MAYSP G
Sbjct: 176 QVECSIGFHQVKLRKFCNREGILIMAYSPLG 206
>UniRef50_P22045 Cluster: Probable reductase; n=101; cellular
organisms|Rep: Probable reductase - Leishmania major
Length = 284
Score = 153 bits (370), Expect = 6e-36
Identities = 83/208 (39%), Positives = 122/208 (58%)
Frame = +2
Query: 89 VQAPCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEE 268
V + L G +P LG + A AV WA+ AGYRHIDTAA+Y++EE
Sbjct: 4 VDKAMVTLSNGVKMPQFGLGVWQSPAGE-----VTENAVNWALCAGYRHIDTAAIYKNEE 58
Query: 269 QVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFP 448
VG G+ A+G V RE++F+TTKLWN + + + A +ES +KLG+DYIDLYLIH+P
Sbjct: 59 SVGAGLR---ASG-VPREDVFITTKLWNTEQGYESTLAAFEESRQKLGVDYIDLYLIHWP 114
Query: 449 IATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIE 628
K S + YL++W+ + + R+IGVSNF+ + +++ + P++NQ+E
Sbjct: 115 -RGKDILSKEGKKYLDSWRAFEQLYKEKKVRAIGVSNFHIHHLEDVLAMCTVTPMVNQVE 173
Query: 629 VNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
++P N Q L A C + I V A+SP G
Sbjct: 174 LHPLNNQADLRAFCDAKQIKVEAWSPLG 201
>UniRef50_Q7ZWA4 Cluster: Zgc:56622; n=6; cellular organisms|Rep:
Zgc:56622 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 289
Score = 152 bits (368), Expect = 1e-35
Identities = 75/178 (42%), Positives = 107/178 (60%), Gaps = 11/178 (6%)
Frame = +2
Query: 212 AIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQ 391
AI AGYRHIDTA Y++E VG I I G++ R+++F+ +KLW HA + +
Sbjct: 9 AIAAGYRHIDTAFCYRNEVDVGMAIQNKIQQGIIRRQDMFIVSKLWGTHHAPEDIPVCFN 68
Query: 392 ESLKKLGLDYIDLYLIHFPIATK-------PDDS----PDNIDYLETWQGMQDARQLGLA 538
+SL L LDY+D YL+HFP+ K P+ +IDY++ W+GM+ + G
Sbjct: 69 KSLSDLQLDYLDQYLVHFPVGLKKVGDELFPERDGKILTTDIDYVDVWRGMEALKATGKV 128
Query: 539 RSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+SIGVSNF QI RL+S + I P +NQ+E++P Q L +C S IA+ A+SPFG
Sbjct: 129 KSIGVSNFTMEQIDRLLSVAKIPPAVNQVELHPYLVQSDLIDYCKSKNIALTAHSPFG 186
>UniRef50_UPI0000498F1F Cluster: oxidoreductase, aldo/keto reductase
family; n=2; Entamoeba histolytica HM-1:IMSS|Rep:
oxidoreductase, aldo/keto reductase family - Entamoeba
histolytica HM-1:IMSS
Length = 305
Score = 150 bits (364), Expect = 3e-35
Identities = 88/205 (42%), Positives = 118/205 (57%), Gaps = 4/205 (1%)
Frame = +2
Query: 110 LHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 289
L+ G +P + LGT V +AV AI+ GYRHID A Y +E++VG GI
Sbjct: 7 LNNGYKIPKLGLGTWMSAN------GEVGKAVEIAIKNGYRHIDCAKAYGNEKEVGDGIK 60
Query: 290 EAIANGLVTREELFVTTKLWN-DKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP- 463
AIA G V REELFVTTKLW+ DKH D V PA ESLKKL L+Y+DLY+IH P+
Sbjct: 61 SAIAKGYVKREELFVTTKLWSTDKHKED-VRPACLESLKKLQLEYLDLYIIHIPLTADKK 119
Query: 464 --DDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNP 637
+ + + I ETW+ M+ + GL +SIGVSNFN ++ L++ + I+P +NQ E +
Sbjct: 120 TGEFTEEIIPIEETWREMEKLVEEGLVKSIGVSNFNIKKLEELLAIAKIQPAVNQFEFHI 179
Query: 638 TNTQEPLXAHCXSLGIAVMAYSPFG 712
+ L C I + Y P G
Sbjct: 180 YYQRPKLHQFCKKHNIHITGYCPLG 204
>UniRef50_Q88SL1 Cluster: Oxidoreductase; n=51; Lactobacillales|Rep:
Oxidoreductase - Lactobacillus plantarum
Length = 286
Score = 150 bits (364), Expect = 3e-35
Identities = 86/201 (42%), Positives = 119/201 (59%)
Frame = +2
Query: 110 LHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 289
L+ G +P V G GT + D +V A++AGYRHIDTAA Y +EE VG+
Sbjct: 13 LNNGTKIPIV----GFGTWQTPDG-QVAYDSVLAALKAGYRHIDTAAAYGNEESVGK--- 64
Query: 290 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDD 469
AIA+ V RE+LFVTTKLWN H D AL SL KLGLDY+DLYLIH+P D
Sbjct: 65 -AIADSGVAREDLFVTTKLWNADHGYDAAKKALDTSLAKLGLDYVDLYLIHWPNPAAMRD 123
Query: 470 SPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQ 649
+ + ++ +TW+ M++A AR+IGVSNF + L+ + + P +NQI +NP++ +
Sbjct: 124 NWEQLN-ADTWRAMEEAYTARKARAIGVSNFRPKHLDALLKTAKVVPAVNQIFLNPSDME 182
Query: 650 EPLXAHCXSLGIAVMAYSPFG 712
+ + A+ I AYSP G
Sbjct: 183 DEVVAYNRKHDILSEAYSPLG 203
>UniRef50_Q6NII7 Cluster: Putative oxidoreductase; n=2;
Corynebacterium|Rep: Putative oxidoreductase -
Corynebacterium diphtheriae
Length = 290
Score = 150 bits (363), Expect = 4e-35
Identities = 80/205 (39%), Positives = 121/205 (59%)
Frame = +2
Query: 98 PCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 277
P I L+ G +P + GT + + D+ VR A IE GYRHIDTA++Y++EE+VG
Sbjct: 12 PTITLNDGTEMPAIGFGTYK--LREQDAYRAVRSA----IEVGYRHIDTASLYKNEEEVG 65
Query: 278 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 457
+ +A+AI G V R+ELF+TTK+WND H + QESL +LGLDYID ++H+P
Sbjct: 66 RAVADAITAGEVARDELFITTKVWNDMHGDQLTQRSFQESLHRLGLDYIDCCMVHWP--- 122
Query: 458 KPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNP 637
P Y+E++ + + LG +S+ V+NF + +V+ + I PV+NQ+E++P
Sbjct: 123 ----WPQKGLYVESFAALAKIQGLGQLQSVAVANFYPEVLREIVAETGIAPVLNQVELHP 178
Query: 638 TNTQEPLXAHCXSLGIAVMAYSPFG 712
+Q A LG+ A+SP G
Sbjct: 179 GFSQAEQRAVDRELGVVTEAWSPLG 203
>UniRef50_Q23320 Cluster: Putative uncharacterized protein; n=4;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 320
Score = 150 bits (363), Expect = 4e-35
Identities = 81/211 (38%), Positives = 124/211 (58%), Gaps = 1/211 (0%)
Frame = +2
Query: 83 MAVQAPCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQD 262
M+ + P L G +P + LGT + T + ++ +R AV AGYRHIDTA +YQ+
Sbjct: 1 MSSKVPIFTLSNGVLMPSIGLGTWQMTGEEGKTV--IRNAVL----AGYRHIDTATLYQN 54
Query: 263 EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIH 442
E Q+G +AE A G++ RE++F+TTK + + A D V AL+ SLK+L LDY+DLYL H
Sbjct: 55 EHQIGDALAELFAEGILKREDIFITTKAFCHEVAPDVVEEALRNSLKRLRLDYVDLYLAH 114
Query: 443 FPIATKPDDS-PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVIN 619
P +TK D S ++ + W+G + LGL ++IGVSNFN +QI R+++ + +
Sbjct: 115 IPASTKDDGSFRSDVKVEDIWRGFEKVYGLGLTKAIGVSNFNESQIVRIMNIQKVPIHAS 174
Query: 620 QIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
Q+E++ Q+ C I + AY+ G
Sbjct: 175 QLELHLYLPQKAHRELCKKHNILITAYATLG 205
>UniRef50_P14065 Cluster: Protein GCY; n=13; Saccharomycetales|Rep:
Protein GCY - Saccharomyces cerevisiae (Baker's yeast)
Length = 312
Score = 150 bits (363), Expect = 4e-35
Identities = 90/224 (40%), Positives = 136/224 (60%), Gaps = 21/224 (9%)
Frame = +2
Query: 104 IQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 283
+ L+ G +P + LGT + +K +D+ +AV A++ GYRHIDTAA+Y++E+QVGQ
Sbjct: 12 LSLNTGAQIPQIGLGTWQ--SKENDAY----KAVLTALKDGYRHIDTAAIYRNEDQVGQ- 64
Query: 284 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFP----- 448
AI + V REE+FVTTKLW +H +V AL +SLK+LGLDY+DLYL+H+P
Sbjct: 65 ---AIKDSGVPREEIFVTTKLWCTQHHEPEV--ALDQSLKRLGLDYVDLYLMHWPARLDP 119
Query: 449 ----------IATKPDDSP----DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRL 586
+ TK D S N ++++TW+ MQ+ + G +++GVSNF+ + L
Sbjct: 120 AYIKNEDILSVPTKKDGSRAVDITNWNFIKTWELMQELPKTGKTKAVGVSNFSINNLKDL 179
Query: 587 VSN--SYIRPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+++ + + P NQ+E++P Q+ L C S GI V AYSP G
Sbjct: 180 LASQGNKLTPAANQVEIHPLLPQDELINFCKSKGIVVEAYSPLG 223
>UniRef50_Q7ZA52 Cluster: Aldose reductase; n=6; Pezizomycotina|Rep:
Aldose reductase - Magnaporthe grisea (Rice blast
fungus) (Pyricularia grisea)
Length = 312
Score = 149 bits (361), Expect = 7e-35
Identities = 85/215 (39%), Positives = 127/215 (59%), Gaps = 14/215 (6%)
Frame = +2
Query: 110 LHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 289
L+ G +P LGT +G +++AV AI++GYR ID A VY +EE+VGQGI
Sbjct: 8 LNTGAKIPAFGLGTWQGDK------GVIKEAVLTAIKSGYRLIDGAYVYGNEEEVGQGIR 61
Query: 290 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP-- 463
EAI++G+V RE+LFV +K W R ++ L +SLK LGLDY+DLYL+H+PI P
Sbjct: 62 EAISSGIVKREDLFVVSKCWATYTTRCEL--GLDQSLKLLGLDYVDLYLVHWPILMNPEG 119
Query: 464 ---------DDSPDNI---DYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR 607
D S D I ++++TW+ M+ G +++GVSN++ + +L+ ++
Sbjct: 120 NDEKFPKHADGSRDIIHTHNHVDTWKLMEKLPATGKTKAVGVSNYSKAWLEQLLPHATTV 179
Query: 608 PVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
P +NQ+E +P Q+ L C GI +MAYSP G
Sbjct: 180 PAVNQVENHPQLPQQELVDFCKEKGIHIMAYSPLG 214
>UniRef50_P51857 Cluster: 3-oxo-5-beta-steroid 4-dehydrogenase (EC
1.3.1.3) (Delta(4)-3- ketosteroid 5-beta-reductase);
n=124; cellular organisms|Rep: 3-oxo-5-beta-steroid
4-dehydrogenase (EC 1.3.1.3) (Delta(4)-3- ketosteroid
5-beta-reductase) - Homo sapiens (Human)
Length = 326
Score = 147 bits (356), Expect = 3e-34
Identities = 84/216 (38%), Positives = 118/216 (54%), Gaps = 13/216 (6%)
Frame = +2
Query: 104 IQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 283
I L G +P + LGT + S +V AI+ GYRHID A +YQ+E +VG+
Sbjct: 10 IPLSDGNSIPIIGLGTY--SEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEA 67
Query: 284 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 463
I E IA G V RE++F KLW H + V P L+ +L+ L LDY+DLY+I P+A KP
Sbjct: 68 IREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKP 127
Query: 464 DDS----PDNIDYL-------ETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI-- 604
D +N +L TW+ M+ + GL +S+GVSNFN Q+ +++ +
Sbjct: 128 GDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKH 187
Query: 605 RPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+PV NQ+E +P TQ L C I + AYSP G
Sbjct: 188 KPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLG 223
>UniRef50_Q0VGY1 Cluster: 3-alpha-hydroxysteroid dehydrogenase;
n=13; Tetrapoda|Rep: 3-alpha-hydroxysteroid
dehydrogenase - Xenopus tropicalis (Western clawed frog)
(Silurana tropicalis)
Length = 324
Score = 147 bits (355), Expect = 4e-34
Identities = 84/216 (38%), Positives = 122/216 (56%), Gaps = 13/216 (6%)
Frame = +2
Query: 104 IQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 283
++L+ G +P + GT K S+ V AI+ GYRHID A +Y +EE+VG+
Sbjct: 9 VELNDGHKMPVIGFGT-YAPPKFPKSLAEEGTKV--AIDVGYRHIDCAFLYGNEEEVGRA 65
Query: 284 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 463
I IA+G V RE++F T KLW+ H ++V PAL++SLK L LDY+DL++IH P+ KP
Sbjct: 66 IRAKIADGTVKREDVFYTGKLWSTSHTPERVRPALEKSLKDLQLDYMDLFIIHMPMEFKP 125
Query: 464 DDS--P---------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI-- 604
D P N D +TW+ ++ + GL RSIGVSNFN Q+ +++ +
Sbjct: 126 GDDLFPADENGKFIYHNTDLRDTWKALEKCKDAGLVRSIGVSNFNHKQLELILNMPGLKY 185
Query: 605 RPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+PV NQ+E + Q L C S I ++ YS G
Sbjct: 186 KPVCNQVECHVYLNQSKLLEFCKSKDIVLVGYSVLG 221
>UniRef50_Q55FL3 Cluster: Aldo-keto reductase; n=2; Dictyostelium
discoideum AX4|Rep: Aldo-keto reductase - Dictyostelium
discoideum AX4
Length = 321
Score = 146 bits (354), Expect = 5e-34
Identities = 83/218 (38%), Positives = 125/218 (57%), Gaps = 16/218 (7%)
Frame = +2
Query: 107 QLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGI 286
+L+ G +P + LGT S++ V A+ A++ GYRHID AA Y +E+ +G +
Sbjct: 18 KLNDGNQIPSIGLGT-----YYSENPGEVGDAINNALKNGYRHIDGAAFYGNEKVIGNSL 72
Query: 287 AEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA---T 457
E G + RE++F T+KLWN H + VV ++++ LG+ Y+DLYLIH+PIA +
Sbjct: 73 KEIFKEGEIKREDIFYTSKLWNSCHNSNLVVKHCVKTIEDLGIGYLDLYLIHWPIAFENS 132
Query: 458 KP--------DDSPDN-----IDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNS 598
P D N + ETWQ M+ +LGL +SIGVSNFN + L++ +
Sbjct: 133 NPLGLTIEPLRDQNGNPIIAPVSIRETWQEMEKLVELGLVKSIGVSNFNVQNLVDLLTYA 192
Query: 599 YIRPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
I+PV+NQ+E++P TQ L +C I ++AYSP G
Sbjct: 193 KIKPVVNQVEIHPYLTQFKLQEYCDKYEIKLVAYSPLG 230
>UniRef50_Q03XK0 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=3; Lactobacillales|Rep: Aldo/keto
reductase of diketogulonate reductase family -
Leuconostoc mesenteroides subsp. mesenteroides (strain
ATCC 8293 /NCDO 523)
Length = 292
Score = 146 bits (353), Expect = 7e-34
Identities = 82/200 (41%), Positives = 115/200 (57%)
Frame = +2
Query: 110 LHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 289
L +G +P + G + K + +QAV AI+ GYR IDTAA Y +E +VG+ I
Sbjct: 6 LASGIEMPLLGFGVFQVQEKGA-----AKQAVLDAIKTGYRLIDTAASYGNEREVGEAIL 60
Query: 290 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDD 469
EAI G+V REELFVT+K+W + Q A+Q SL++L LDY+DLYLIH P
Sbjct: 61 EAINQGIVKREELFVTSKMWVQDVSAQQATAAIQSSLQRLNLDYLDLYLIHQPYN----- 115
Query: 470 SPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQ 649
D W+ M+ A + G ++IGVSNF+ Q+T L S I+P++NQIEVNP
Sbjct: 116 -----DVFGAWRAMESAYRSGQLKAIGVSNFDIAQLTNLAEFSDIKPMLNQIEVNPFQQN 170
Query: 650 EPLXAHCXSLGIAVMAYSPF 709
+ + G+ V A++PF
Sbjct: 171 KKDITYFSQYGVQVEAWAPF 190
>UniRef50_Q0PGJ6 Cluster: Aldo-keto reductase; n=32;
Magnoliophyta|Rep: Aldo-keto reductase - Arabidopsis
thaliana (Mouse-ear cress)
Length = 315
Score = 145 bits (352), Expect = 9e-34
Identities = 81/216 (37%), Positives = 119/216 (55%), Gaps = 6/216 (2%)
Frame = +2
Query: 83 MAVQAPCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQD 262
MA +L+ G P V LGT + S V AV A++ GYRHID A +Y +
Sbjct: 1 MANAITFFKLNTGAKFPSVGLGTWQA------SPGLVGDAVAAAVKIGYRHIDCAQIYGN 54
Query: 263 EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIH 442
E+++G + + + +V RE+LF+T+KLW H V AL +LK L L+Y+DLYLIH
Sbjct: 55 EKEIGAVLKKLFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIH 114
Query: 443 FPIATKPDD---SPDN---IDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI 604
+P K P+N +D TW+ M+ G AR+IGVSNF+ ++ L+ + +
Sbjct: 115 WPARIKKGSVGIKPENLLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELARV 174
Query: 605 RPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
P +NQ+E +P+ Q L C S G+ + AYSP G
Sbjct: 175 PPAVNQVECHPSWRQTKLQEFCKSKGVHLSAYSPLG 210
>UniRef50_Q9NAI5 Cluster: Putative uncharacterized protein; n=3;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 316
Score = 145 bits (352), Expect = 9e-34
Identities = 81/214 (37%), Positives = 124/214 (57%), Gaps = 11/214 (5%)
Frame = +2
Query: 104 IQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 283
++L++G +P + LGT + +K + V A+ A+ AGYRHID A VYQ++++VG+
Sbjct: 5 LKLNSGYSIPAIGLGTWQ--SKPGE----VAAAIKTAVAAGYRHIDCAHVYQNQKEVGEA 58
Query: 284 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFP--IAT 457
+ E + G V REELF+T+K+WN H+ + + L L L Y+DL LIH+P A
Sbjct: 59 LKEILDEGKVKREELFITSKVWNTFHSEAKAHENIDIILSDLQLSYVDLMLIHWPQGYAE 118
Query: 458 KPDDSP---------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRP 610
+ P ++DYLETW+ + A++ G RSIG+SNF +QI R+ + ++P
Sbjct: 119 GAELFPAGENGKMRYSDVDYLETWKAFEAAQKAGKCRSIGLSNFTHSQIQRVWDAAEVKP 178
Query: 611 VINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
Q+E++P TQ L C GI V+ YSP G
Sbjct: 179 ACLQVELHPYFTQVKLREFCKEKGIVVVGYSPLG 212
>UniRef50_Q10494 Cluster: Probable oxidoreductase C26F1.07; n=2;
Schizosaccharomyces pombe|Rep: Probable oxidoreductase
C26F1.07 - Schizosaccharomyces pombe (Fission yeast)
Length = 321
Score = 145 bits (352), Expect = 9e-34
Identities = 83/209 (39%), Positives = 124/209 (59%), Gaps = 11/209 (5%)
Frame = +2
Query: 119 GXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAI 298
G +P + LGT R + + AV A++ GYRHID AA+Y +E++VG GI E+
Sbjct: 21 GSKIPGLGLGTWRSEPNQT------KNAVKTALQYGYRHIDAAAIYGNEDEVGDGIKES- 73
Query: 299 ANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK------ 460
G V R++++VT+KLW + HA + V AL+++LK L LDY+D YLIH+P++ K
Sbjct: 74 --G-VPRKDIWVTSKLWCNAHAPEAVPKALEKTLKDLKLDYLDEYLIHWPVSFKTGEDKF 130
Query: 461 PDDSPDNIDYL-----ETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQI 625
P D N+ Y ETW+ M+ + G R IG+SNFN T + R++ + ++P ++Q+
Sbjct: 131 PKDKDGNLIYEKNPIEETWKAMEKLLETGKVRHIGLSNFNDTNLERILKVAKVKPAVHQM 190
Query: 626 EVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
E++P Q LGI V AYSPFG
Sbjct: 191 ELHPFLPQTEFVEKHKKLGIHVTAYSPFG 219
>UniRef50_Q1U9L6 Cluster: 2,5-didehydrogluconate reductase; n=3;
Lactobacillus|Rep: 2,5-didehydrogluconate reductase -
Lactobacillus reuteri 100-23
Length = 288
Score = 145 bits (351), Expect = 1e-33
Identities = 86/202 (42%), Positives = 118/202 (58%), Gaps = 1/202 (0%)
Frame = +2
Query: 110 LHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 289
L+ G +P V GT R A ++ QAV AIE GYRHIDTAAVY +EE VG+GI
Sbjct: 13 LNNGVKIPCVGYGTFRTPADVAE------QAVKEAIETGYRHIDTAAVYGNEEAVGKGIK 66
Query: 290 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP-D 466
++ G + RE+LFVT+KLWN +Q A QE+L +L +DY+DLYLIH+P K
Sbjct: 67 DS---G-IKREDLFVTSKLWNTNRGYEQTKKAFQETLDRLQMDYLDLYLIHWPANEKQFG 122
Query: 467 DSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNT 646
D I+ ETW+ M+D G R+IGVSNF I L+ + + P ++QIEV+P
Sbjct: 123 DDAAKIN-AETWRAMEDLYNEGKIRAIGVSNFMPHHIAELMKTAKVAPAVDQIEVHPGWP 181
Query: 647 QEPLXAHCXSLGIAVMAYSPFG 712
+ + + I V A++P G
Sbjct: 182 HTEVVKYLQAHNILVEAWAPLG 203
>UniRef50_P27800 Cluster: Aldehyde reductase 1; n=18; root|Rep:
Aldehyde reductase 1 - Sporobolomyces salmonicolor
Length = 323
Score = 145 bits (351), Expect = 1e-33
Identities = 86/217 (39%), Positives = 121/217 (55%), Gaps = 16/217 (7%)
Frame = +2
Query: 110 LHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 289
L+ G L V GT + V Q V AIE GYRH+D A VY ++ +VG I
Sbjct: 7 LNTGASLELVGYGTWQAAP------GEVGQGVKVAIETGYRHLDLAKVYSNQPEVGAAIK 60
Query: 290 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPD- 466
EA G V RE+LF+T+KLWN+ H +QV PAL ++LK+LGL+Y+DLYLIH+P+A P+
Sbjct: 61 EA---G-VKREDLFITSKLWNNSHRPEQVEPALDDTLKELGLEYLDLYLIHWPVAFPPEG 116
Query: 467 DSPDN---------------IDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSY 601
D N + ++TW+ M G ++IGVSNF+A + ++ +
Sbjct: 117 DITQNLFPKANDKEVKLDLEVSLVDTWKAMVKLLDTGKVKAIGVSNFDAKMVDAIIEATG 176
Query: 602 IRPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+ P +NQIE +P Q L AH + I + AYSP G
Sbjct: 177 VTPSVNQIERHPLLLQPELIAHHKAKNIHITAYSPLG 213
>UniRef50_P06632 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=8; Actinomycetales|Rep: 2,5-diketo-D-gluconic acid
reductase A - Corynebacterium sp. (strain ATCC 31090)
Length = 278
Score = 144 bits (350), Expect = 2e-33
Identities = 82/205 (40%), Positives = 121/205 (59%)
Frame = +2
Query: 98 PCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 277
P I L+ G +P LG G +D+ ++AV A+E GYRHIDTAA+Y +EE VG
Sbjct: 4 PSIVLNDGNSIPQ--LGYGVFKVPPADT----QRAVEEALEVGYRHIDTAAIYGNEEGVG 57
Query: 278 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 457
IA A+G + R++LF+TTKLWND+H D+ A+ ESL KL LD +DLYL+H+P
Sbjct: 58 AAIA---ASG-IARDDLFITTKLWNDRHDGDEPAAAIAESLAKLALDQVDLYLVHWP--- 110
Query: 458 KPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNP 637
+P +Y+ W+ M + R GL RSIGVSN + R+V+ + + P +NQIE++P
Sbjct: 111 ----TPAADNYVHAWEKMIELRAAGLTRSIGVSNHLVPHLERIVAATGVVPAVNQIELHP 166
Query: 638 TNTQEPLXAHCXSLGIAVMAYSPFG 712
Q + + + + ++ P G
Sbjct: 167 AYQQREITDWAAAHDVKIESWGPLG 191
>UniRef50_Q8F1G4 Cluster: Aldehyde reductase; n=8; Bacteria|Rep:
Aldehyde reductase - Leptospira interrogans
Length = 278
Score = 144 bits (349), Expect = 2e-33
Identities = 81/201 (40%), Positives = 117/201 (58%)
Frame = +2
Query: 104 IQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 283
I L+ G +P + LG + + S ++AV A+EAGYRHIDTA +Y +E VGQ
Sbjct: 12 IMLNNGISMPILGLGVWK-----TKSGKECKEAVLNALEAGYRHIDTARIYDNEVDVGQA 66
Query: 284 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 463
I E+ G + R+E+F+TTKLWN D+ AL+ SL +LG+D++DLYLIHFP+ +K
Sbjct: 67 IRES---G-IPRKEIFITTKLWNADQGSDKTRKALENSLDRLGIDFVDLYLIHFPVTSKR 122
Query: 464 DDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTN 643
DS W+ ++ L ++IGVSN+ +T L+ NS I P +NQ+E +P
Sbjct: 123 MDS---------WKELEKLYHDKLCKAIGVSNYTIIHLTELLKNSQITPAVNQVEFHPFL 173
Query: 644 TQEPLXAHCXSLGIAVMAYSP 706
Q L +C I + AYSP
Sbjct: 174 NQIHLLEYCKKHKIQLEAYSP 194
>UniRef50_A2EHN6 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=10; Trichomonas vaginalis|Rep:
Oxidoreductase, aldo/keto reductase family protein -
Trichomonas vaginalis G3
Length = 312
Score = 144 bits (349), Expect = 2e-33
Identities = 82/209 (39%), Positives = 120/209 (57%), Gaps = 16/209 (7%)
Frame = +2
Query: 152 GRGTAKXSDSIXXVRQAVYWAIE-AGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREEL 328
G GT +D ++ A+++AIE G RHIDTA Y ++ +G+ + E A G + RE++
Sbjct: 7 GFGTYLANDP-AKLKAALHYAIEECGVRHIDTAFAYYNQNVIGETLKEIFAKGKIKREDM 65
Query: 329 FVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK----------PDDSP- 475
F+TTKLW H +D V P L E+L +L L Y+DL+LIH PIA K P D
Sbjct: 66 FITTKLWCTHHRKDLVEPELHENLAQLQLSYVDLFLIHQPIAFKSLPAKDGTMMPKDEKG 125
Query: 476 ----DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTN 643
+ ID LET+ M++ ++ GL R IGVSNF+ Q+ R+ N I+P NQ+E N
Sbjct: 126 KIQYEQIDILETYHAMEECQKKGLTRHIGVSNFSIEQLERIWFNCEIKPYANQVECNIYR 185
Query: 644 TQEPLXAHCXSLGIAVMAYSPFGFVVSRG 730
+PL ++C S I +MA++ G +G
Sbjct: 186 QFKPLLSYCESHNIYLMAHTTIGHPPLKG 214
>UniRef50_Q5KI95 Cluster: Aldo-keto reductase, putative; n=14;
Dikarya|Rep: Aldo-keto reductase, putative -
Cryptococcus neoformans (Filobasidiella neoformans)
Length = 353
Score = 144 bits (349), Expect = 2e-33
Identities = 90/235 (38%), Positives = 136/235 (57%), Gaps = 16/235 (6%)
Frame = +2
Query: 56 TFTRL-LHAAMAVQAPC-IQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGY 229
TFT L + ++ + AP +L+ G +P + LGT + AK + VRQAV A++AGY
Sbjct: 21 TFTILPIFNSLIMSAPTSFKLNTGASIPAIGLGTWQ--AKAGE----VRQAVAHALKAGY 74
Query: 230 RHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKL 409
RHID A YQ+E++VG GI ++ G V R E+F+T+K+W+ H D+V L +LK L
Sbjct: 75 RHIDGALCYQNEDEVGLGIKDS---G-VPRSEIFLTSKVWSSYH--DRVEECLDTTLKSL 128
Query: 410 GLDYIDLYLIHFPIATKPDDS-------PD---NIDY----LETWQGMQDARQLGLARSI 547
DY+DLYLIH+P+ P+ + PD N+D+ +TW M+D + G A++I
Sbjct: 129 QTDYLDLYLIHWPVRLAPNGTHPLFPVKPDGSRNLDWDWDQAKTWAQMEDVLKKGKAKAI 188
Query: 548 GVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
G+SN I ++ + P +NQ+E++P Q L +C GI + AYSP G
Sbjct: 189 GLSNAGIPIIEHIIKTGKVTPAVNQVELHPYCPQHALLKYCKEKGILLEAYSPLG 243
>UniRef50_A1D4E3 Cluster: D-xylose reductase (Xyl1), putative; n=5;
Pezizomycotina|Rep: D-xylose reductase (Xyl1), putative
- Neosartorya fischeri (strain ATCC 1020 / DSM 3700 /
NRRL 181)(Aspergillus fischerianus (strain ATCC 1020 /
DSM 3700 / NRRL 181))
Length = 321
Score = 144 bits (349), Expect = 2e-33
Identities = 89/221 (40%), Positives = 118/221 (53%), Gaps = 16/221 (7%)
Frame = +2
Query: 98 PCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 277
P +L++G +P V G G K ++ +Y AI+AGYR D A Y +E + G
Sbjct: 4 PSTKLNSGYDMPLV----GFGLWKVNNE--TCADQIYHAIKAGYRLFDGACDYGNEVEAG 57
Query: 278 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 457
+G+A AI G+V RE+LF+ +KLWN H D+V P ++ L GLDY DL+++HFPIA
Sbjct: 58 KGVARAIQEGIVKREDLFIVSKLWNSFHDGDRVEPICRKQLADWGLDYFDLFIVHFPIAL 117
Query: 458 KPDDSP----------------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLV 589
K D N ETW M+ LARSIGVSNF+A + L+
Sbjct: 118 KYVDPAVRYPPGWLSENNKLEFSNASIQETWTAMESLVDKKLARSIGVSNFSAQLLMDLL 177
Query: 590 SNSYIRPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+ IRP QIE +P TQE L + GIAV AYS FG
Sbjct: 178 RYARIRPATLQIEHHPYLTQERLVTYAQKEGIAVTAYSSFG 218
>UniRef50_P23901 Cluster: Aldose reductase; n=9; Poaceae|Rep: Aldose
reductase - Hordeum vulgare (Barley)
Length = 320
Score = 144 bits (349), Expect = 2e-33
Identities = 83/208 (39%), Positives = 127/208 (61%), Gaps = 7/208 (3%)
Frame = +2
Query: 110 LHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 289
L +G +P V LGT R SD+ VR A+ EAGYRH+DTAA Y E++VG+G+
Sbjct: 18 LKSGHAMPAVGLGTWRA---GSDTAHSVRTAI---TEAGYRHVDTAAEYGVEKEVGKGLK 71
Query: 290 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK--- 460
A+ G + R++LFVT+K+W A ++V PAL+ +LK L LDYIDLY IH+P K
Sbjct: 72 AAMEAG-IDRKDLFVTSKIWCTNLAPERVRPALENTLKDLQLDYIDLYHIHWPFRLKDGA 130
Query: 461 --PDDSPDNIDY-LE-TWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIE 628
P ++ + +++ +E W+ M++ + GL + IGV N+ T++ RL+ ++ I P + Q+E
Sbjct: 131 HMPPEAGEVLEFDMEGVWKEMENLVKDGLVKDIGVCNYTVTKLNRLLRSAKIPPAVCQME 190
Query: 629 VNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
++P + + C GI V AYSP G
Sbjct: 191 MHPGWKNDKIFEACKKHGIHVTAYSPLG 218
>UniRef50_P28475 Cluster: NADP-dependent D-sorbitol-6-phosphate
dehydrogenase; n=71; Magnoliophyta|Rep: NADP-dependent
D-sorbitol-6-phosphate dehydrogenase - Malus domestica
(Apple) (Malus sylvestris)
Length = 310
Score = 144 bits (348), Expect = 3e-33
Identities = 81/218 (37%), Positives = 119/218 (54%), Gaps = 15/218 (6%)
Frame = +2
Query: 104 IQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 283
+ L +G +P + LG R D + ++ + AI+ GYRH D AA Y+ E VG+
Sbjct: 4 VTLSSGYEMPVIGLGLWR---LEKDEL---KEVILNAIKIGYRHFDCAAHYKSEADVGEA 57
Query: 284 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 463
+AEA GLV REELF+TTK+WN H VV A + SL+KL +DY+DLYL+H+P+ TK
Sbjct: 58 LAEAFKTGLVKREELFITTKIWNSDHG--HVVEACKNSLEKLQIDYLDLYLVHYPMPTKH 115
Query: 464 D---------------DSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNS 598
+ D I +TW+GM+ LGL RSIG+SN+ ++ S
Sbjct: 116 NAIGKTASLLGEDKVLDIDVTISLQQTWEGMEKTVSLGLVRSIGLSNYELFLTRDCLAYS 175
Query: 599 YIRPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
I+P ++Q E +P ++ L C G+ A++P G
Sbjct: 176 KIKPAVSQFETHPYFQRDSLVKFCMKHGVLPTAHTPLG 213
>UniRef50_A7CWF9 Cluster: Aldehyde reductase; n=2; Bacteria|Rep:
Aldehyde reductase - Opitutaceae bacterium TAV2
Length = 347
Score = 143 bits (346), Expect = 5e-33
Identities = 81/233 (34%), Positives = 126/233 (54%), Gaps = 14/233 (6%)
Frame = +2
Query: 56 TFTRLLHAAMAVQAPCIQLHAGXPLPXVALGT-GRGTAKXSDSIXXVRQAVYWAIEAGYR 232
T T L + P L +G +P + +GT G A + V +VY A E GYR
Sbjct: 3 TETATLAPIDPAKIPQRTLASGARMPAIGMGTFGSDHAAPGE----VAASVYAAAELGYR 58
Query: 233 HIDTAAVYQDEEQVGQGIAEAI-ANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKL 409
H D AAVY +E ++G + +N + RE+L++T+KLWNDKHA V+PA ++SL+ L
Sbjct: 59 HFDCAAVYSNEREIGATFRRILTSNTGIRREDLWITSKLWNDKHAEADVIPAFEKSLRDL 118
Query: 410 GLDYIDLYLIHFPI-----------ATKPDDSP-DNIDYLETWQGMQDARQLGLARSIGV 553
GLDY+DLYLIH+P + PD P + ++++TW+ ++ GL R IG
Sbjct: 119 GLDYLDLYLIHWPFPNFHPPGCDVSSRSPDARPYIHAEFMKTWRQLETLHDRGLVRHIGT 178
Query: 554 SNFNATQITRLVSNSYIRPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
SN ++ L+ ++ +RP +N++E++P Q L + I + Y P G
Sbjct: 179 SNMTIAKLQLLLRDARVRPAVNEMELHPHFQQPALFDYVRVRNIVPVGYCPLG 231
>UniRef50_Q7PLK6 Cluster: CG40064-PA; n=1; Drosophila
melanogaster|Rep: CG40064-PA - Drosophila melanogaster
(Fruit fly)
Length = 361
Score = 143 bits (346), Expect = 5e-33
Identities = 71/169 (42%), Positives = 105/169 (62%), Gaps = 12/169 (7%)
Frame = +2
Query: 200 AVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVV 379
AV+ AIE G+RH DTA Y++E+++G+ + I G ++RE +F+TTKLWN H V
Sbjct: 49 AVHCAIETGFRHFDTAYYYENEKEIGEALRTQIKMGNISRENIFLTTKLWNTHHDPRDVR 108
Query: 380 PALQESLKKLGLDYIDLYLIHFPIATK--------PDDSPD----NIDYLETWQGMQDAR 523
++ L+ LG YIDLYL+HFP+ K P + IDYL+TW+ M++
Sbjct: 109 RICEKQLELLGFSYIDLYLMHFPVGYKYVCDEILMPMSGDELQTVEIDYLDTWRAMENLV 168
Query: 524 QLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEPLXAHC 670
+LG+ RSIG+SNFN QI R++ S +PV+NQ+E+ P Q+ L +C
Sbjct: 169 KLGMVRSIGLSNFNMEQIQRIIQCSSSKPVVNQVEIWPGFLQKDLVDYC 217
>UniRef50_Q02198 Cluster: Morphine 6-dehydrogenase; n=5;
Bacteria|Rep: Morphine 6-dehydrogenase - Pseudomonas
putida
Length = 296
Score = 143 bits (346), Expect = 5e-33
Identities = 86/216 (39%), Positives = 128/216 (59%)
Frame = +2
Query: 83 MAVQAPCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQD 262
MA ++P I L+ G +P + LG +A+ + S A+ AI +GYR IDTA Y +
Sbjct: 1 MAGKSPLINLNNGVKMPALGLGVFAASAEETAS------AIASAISSGYRLIDTARSYNN 54
Query: 263 EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIH 442
E QVG+GI N V R E+FVTTKL+N + ++ + A ESL +LGLDY+DLYL+H
Sbjct: 55 EAQVGEGIR----NSGVDRAEMFVTTKLFNCDYGYERALRAFDESLGRLGLDYVDLYLLH 110
Query: 443 FPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQ 622
+P TK ++ +++W+ + G AR+IGV NF Q+ L++ S + P +NQ
Sbjct: 111 WP--TKDWNAT-----IQSWKAAEKILGDGRARAIGVCNFLEDQLDELIAASDVVPAVNQ 163
Query: 623 IEVNPTNTQEPLXAHCXSLGIAVMAYSPFGFVVSRG 730
IE++P Q+PL A +LGI A+SP G ++ G
Sbjct: 164 IELHPYFAQKPLLAKNRALGIVTEAWSPIGGAINDG 199
>UniRef50_Q7N0E4 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=2; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase
A - Photorhabdus luminescens subsp. laumondii
Length = 292
Score = 142 bits (345), Expect = 6e-33
Identities = 83/203 (40%), Positives = 120/203 (59%)
Frame = +2
Query: 98 PCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 277
P I+L G +P + LG+ SD + + ++ A++ GYR IDTAA+Y +E+ VG
Sbjct: 5 PIIRLADGNHMPQLGLGSW-----ASDD-QQIAETIHAALDIGYRAIDTAAIYNNEKGVG 58
Query: 278 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 457
+ E + RE++FVTTKLWND+H + AL ESL+KL LDY+DLYLIH+P
Sbjct: 59 NALQETD----IPREDIFVTTKLWNDRHLDARA--ALTESLEKLQLDYVDLYLIHWP--- 109
Query: 458 KPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNP 637
+P Y+ WQ + + ++ GL RSIGVSNF I RL++ + + PVINQIE++P
Sbjct: 110 ----APPQDQYVGAWQQLIELQKEGLIRSIGVSNFQPEHIQRLINETGVHPVINQIELHP 165
Query: 638 TNTQEPLXAHCXSLGIAVMAYSP 706
Q L A + I ++SP
Sbjct: 166 LLQQRQLHAWNATHNIVTESWSP 188
>UniRef50_Q41E86 Cluster: 2,5-didehydrogluconate reductase; n=2;
Bacteria|Rep: 2,5-didehydrogluconate reductase -
Exiguobacterium sibiricum 255-15
Length = 274
Score = 142 bits (345), Expect = 6e-33
Identities = 70/172 (40%), Positives = 111/172 (64%)
Frame = +2
Query: 191 VRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARD 370
V +AV A+ GYR IDTA +Y++E VG+ A+ + + RE++F+TTK+WN +
Sbjct: 27 VYEAVREALRVGYRSIDTAMIYENEAGVGR----ALKDSGIPREDIFLTTKVWNKDQGYE 82
Query: 371 QVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIG 550
+ + A + SL+KLG+DY+DLYLIH+P+ PD Y++TW+ ++ + G A++IG
Sbjct: 83 RTLAAFETSLQKLGVDYVDLYLIHWPM-------PDEDLYMDTWRALEQLYRDGKAKAIG 135
Query: 551 VSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSP 706
VSNF+ +TR++ + P +NQIE++P +QE + A C GI V A+SP
Sbjct: 136 VSNFHIPHLTRVLEEGTVVPAVNQIELHPFLSQEAIRAFCQKNGIVVEAWSP 187
>UniRef50_Q96UH3 Cluster: Aldehyde reductase; n=13;
Pezizomycotina|Rep: Aldehyde reductase - Coccidioides
posadasii
Length = 314
Score = 142 bits (344), Expect = 8e-33
Identities = 83/221 (37%), Positives = 125/221 (56%), Gaps = 11/221 (4%)
Frame = +2
Query: 83 MAVQAPCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQD 262
MA + +L+ G +P + GT + D AV A+ AGYRHIDTAAVY
Sbjct: 1 MASRHTTFRLNTGEDIPAIGFGTWQDENAQED-------AVLTALSAGYRHIDTAAVYGT 53
Query: 263 EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIH 442
E+ +G+ A+A ++R+ELF+T+KLWN+KH + V A+ +SLK L +DY+DLYL+H
Sbjct: 54 EKAIGR----ALARSRLSRDELFITSKLWNNKHRPEDVEQAIDQSLKNLEIDYLDLYLMH 109
Query: 443 FPIATK------PDDSPDN-----IDYLETWQGMQDARQLGLARSIGVSNFNATQITRLV 589
+P A P DS N IDY++T++ M+ + G ++IG+SNF+ ++ RL+
Sbjct: 110 WPAAFAPGDDMFPKDSQGNSKTVDIDYVDTYKAMEKLVKSGKTKAIGISNFSKGEMERLL 169
Query: 590 SNSYIRPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+ I P + Q+E++P Q S GI V YS G
Sbjct: 170 ESCSIVPAVMQMELHPWLQQNDFVEWLKSKGIHVTQYSSLG 210
>UniRef50_UPI0000588153 Cluster: PREDICTED: hypothetical protein;
n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 333
Score = 141 bits (342), Expect = 1e-32
Identities = 78/216 (36%), Positives = 120/216 (55%), Gaps = 13/216 (6%)
Frame = +2
Query: 104 IQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 283
+ L +G +P V LGT + A V A+ A++AGYRH D A +Y +E++VG
Sbjct: 5 VTLPSGHAMPLVGLGTWKLKADE------VAGAIGAAVDAGYRHFDCALIYGNEKEVGVA 58
Query: 284 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA--- 454
+ EA+ + RE++F+TTK+WN HA++ V SL L LDYIDLY++H+P+
Sbjct: 59 LREAMQRLGLKREDVFITTKVWNTFHAKEDVAECFNRSLTDLQLDYIDLYIMHWPLGFQN 118
Query: 455 ---------TKPDDSP-DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI 604
T+ D ++ YLETW M+D + G +S+G+SNFN+ Q+ ++ +S +
Sbjct: 119 LGPTVMFPRTETGDIVYSDVHYLETWSAMEDLVKTGKCKSLGLSNFNSKQLDDVLQHSTV 178
Query: 605 RPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
P + Q+E +P Q L C + V AYSP G
Sbjct: 179 PPSVLQVESHPFLPQVELLNFCRERSVVVSAYSPLG 214
>UniRef50_A4RQH8 Cluster: Predicted protein; n=2; Ostreococcus|Rep:
Predicted protein - Ostreococcus lucimarinus CCE9901
Length = 337
Score = 141 bits (342), Expect = 1e-32
Identities = 83/201 (41%), Positives = 114/201 (56%), Gaps = 5/201 (2%)
Frame = +2
Query: 119 GXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAI 298
G +P V LGT + A+ ++ VR AV A+ AGY H+D AA Y +E +VG+ + EA
Sbjct: 13 GLRIPRVGLGTWK--ARPNE----VRDAVRDALGAGYAHVDCAAAYANESEVGEALREAF 66
Query: 299 ANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDD--S 472
G RE++FVT+KLWND+ V AL +L LG+ Y+DLYLIH+P+A K
Sbjct: 67 ERGDAKREDVFVTSKLWNDRRRPRDVREALMTTLNDLGVGYLDLYLIHWPVAWKRGTVLQ 126
Query: 473 PD-NIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSN--SYIRPVINQIEVNPTN 643
PD E W ++ GL R IGVSNFN Q+ L + + I+P NQIE +P
Sbjct: 127 PDAEASIAECWSELERCVADGLVRHIGVSNFNEAQLAALCDDPRTKIQPACNQIESHPLW 186
Query: 644 TQEPLXAHCXSLGIAVMAYSP 706
+ + L + S G+ V AYSP
Sbjct: 187 SNDSLVKYSQSKGLTVTAYSP 207
>UniRef50_A7RRF6 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 275
Score = 141 bits (342), Expect = 1e-32
Identities = 75/171 (43%), Positives = 104/171 (60%)
Frame = +2
Query: 194 RQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQ 373
+QAV WA+E GYR IDTAA Y +E++VG EA+ V R E+++ TK+++ H ++
Sbjct: 31 KQAVLWALENGYRMIDTAASYNNEKRVG----EALRESAVPRSEVYLVTKVYHTDHGYEK 86
Query: 374 VVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGV 553
+ A SL LG+DY+DLYLIHFP+ P + + +W+ M + + GL RSIGV
Sbjct: 87 TMKAYDRSLSALGVDYVDLYLIHFPV-------PAGV--VGSWEAMAELQGKGLTRSIGV 137
Query: 554 SNFNATQITRLVSNSYIRPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSP 706
SNFN + L +S I PV+NQIEV+P E L C IA+ AYSP
Sbjct: 138 SNFNIHHLEALQKHSVIPPVVNQIEVHPYLQMEELVDFCRKHSIAIQAYSP 188
>UniRef50_Q8ZI40 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=74; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase
A - Yersinia pestis
Length = 277
Score = 141 bits (342), Expect = 1e-32
Identities = 84/203 (41%), Positives = 116/203 (57%)
Frame = +2
Query: 98 PCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 277
P I+L+ G +P + LG + SI AV A+E GYR IDTAA+Y++EE VG
Sbjct: 5 PLIKLYDGRLMPQLGLGVWQA------SIQETELAVSKALEVGYRSIDTAAIYKNEEGVG 58
Query: 278 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 457
+ + A V R+ELF+TTKLWND Q AL+ SL+KL LDY+DLYLIH+P
Sbjct: 59 KALKAAA----VARDELFITTKLWNDDQHNPQ--QALETSLQKLQLDYVDLYLIHWP--- 109
Query: 458 KPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNP 637
P Y+ W+ + ++ GL RSIGV NF+ + RL+ + I P +NQIE++P
Sbjct: 110 ----DPKQDHYVSAWRELVTLKEQGLIRSIGVCNFHIPHLQRLIDETGIAPTVNQIELHP 165
Query: 638 TNTQEPLXAHCXSLGIAVMAYSP 706
Q L A + IA ++SP
Sbjct: 166 LLQQRQLHAWNATHHIATESWSP 188
>UniRef50_UPI0000E4A7CE Cluster: PREDICTED: similar to LOC553452
protein; n=6; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to LOC553452 protein -
Strongylocentrotus purpuratus
Length = 321
Score = 140 bits (340), Expect = 2e-32
Identities = 89/224 (39%), Positives = 120/224 (53%), Gaps = 14/224 (6%)
Frame = +2
Query: 83 MAVQAPCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQD 262
MA I L G LP + GT + K + V + + AI+ GYRHID A++Y +
Sbjct: 1 MASSNTHIVLPGGRKLPLLGFGTWQ--IKPEE----VGRVIETAIDCGYRHIDEASLYGN 54
Query: 263 EEQVGQGIAEAIANGLVTREELFVTTKLW-NDKHARDQVVPALQESLKKLGLDYIDLYLI 439
E+ VG GI I +G + RE+LFVT+KLW D H +V P+ ++SL LGL Y+DL+LI
Sbjct: 55 EKGVGDGIKAKIDDGTIKREDLFVTSKLWVTDSHP-SRVEPSCRQSLSDLGLAYLDLFLI 113
Query: 440 HFPIATKPDDSP------------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITR 583
H P + P D IDY++TW+ M+ GL R+IGVSNF QI R
Sbjct: 114 HCPTSAVGGKGPFPMDDNGLFIGDDTIDYVDTWRIMESLVDKGLVRAIGVSNFTVAQIQR 173
Query: 584 LVSNSYIRPVIN-QIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
++ P+ N Q+E +P Q L C GI V AYSP G
Sbjct: 174 VLDLPPKYPIANVQVECHPFLAQNELIEFCKKQGITVTAYSPLG 217
>UniRef50_Q05KR9 Cluster: Benzil reductase; n=5; Bacillales|Rep:
Benzil reductase - Bacillus subtilis
Length = 276
Score = 140 bits (340), Expect = 2e-32
Identities = 78/201 (38%), Positives = 123/201 (61%)
Frame = +2
Query: 104 IQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 283
++LH G +P LG + ++ ++V AI+ GYR IDTAA+Y++EE VG G
Sbjct: 9 VKLHNGVEMPWFGLGVFK-----VENGNEATESVKAAIKNGYRSIDTAAIYKNEEGVGIG 63
Query: 284 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 463
I E+ G V REELF+T+K+WN+ + + A ++SL++L LDY+DLYLIH+P K
Sbjct: 64 IKES---G-VAREELFITSKVWNEDQGYETTLAAFEKSLERLQLDYLDLYLIHWPGKDK- 118
Query: 464 DDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTN 643
Y +TW+ ++ + G R+IGVSNF + L+ ++ I+P++NQ+E +P
Sbjct: 119 --------YKDTWRALEKLYKDGKIRAIGVSNFQVHHLEELLKDAEIKPMVNQVEFHPRL 170
Query: 644 TQEPLXAHCXSLGIAVMAYSP 706
TQ+ L +C + GI + A+SP
Sbjct: 171 TQKELRDYCKAQGIQLEAWSP 191
>UniRef50_Q5FK98 Cluster: Oxidoreductase; n=8; Lactobacillales|Rep:
Oxidoreductase - Lactobacillus acidophilus
Length = 285
Score = 140 bits (338), Expect = 4e-32
Identities = 77/201 (38%), Positives = 116/201 (57%)
Frame = +2
Query: 110 LHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 289
L+ G +P + G GT + D ++V A+ GYRHIDTA+ Y +E+ VG+ I
Sbjct: 12 LNNGVKIPII----GFGTWQTPDG-EVAEESVLAALNCGYRHIDTASAYGNEDSVGRAIQ 66
Query: 290 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDD 469
++ N R ELF+TTKLWN H ++ A+ +SL L LDY+D+YLIH+P + D
Sbjct: 67 KSGIN----RHELFITTKLWNSDHGYEKTKKAIDQSLLDLKLDYLDMYLIHWPNPSSMRD 122
Query: 470 SPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQ 649
I+ E+W+ M++A + G R+IGVSNF + L+ + I+PV+NQI +NP++ Q
Sbjct: 123 HWAEIN-AESWRAMEEAVRAGKIRAIGVSNFRKHHLDALMETAEIKPVVNQIFLNPSDLQ 181
Query: 650 EPLXAHCXSLGIAVMAYSPFG 712
+ L + AYSP G
Sbjct: 182 SEVVTENKKLDLLSEAYSPLG 202
>UniRef50_A2R6Z3 Cluster: Catalytic activity: an alcohol + NADP(+)
<=> an aldehyde + NADPH; n=9; Pezizomycotina|Rep:
Catalytic activity: an alcohol + NADP(+) <=> an aldehyde
+ NADPH - Aspergillus niger
Length = 345
Score = 140 bits (338), Expect = 4e-32
Identities = 88/215 (40%), Positives = 121/215 (56%), Gaps = 13/215 (6%)
Frame = +2
Query: 107 QLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGI 286
+L+ G +P V LGT + +K + VR AV A++ GYRHID AAVY +E++VG G+
Sbjct: 8 KLNTGYDMPAVGLGTWQ--SKKDE----VRDAVIAALKCGYRHIDAAAVYGNEQEVGDGM 61
Query: 287 AEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPD 466
+G V REE+F+T+KLWN H + V A+ +SL L DY+DLYLIH+P+A +
Sbjct: 62 R---LSG-VPREEIFLTSKLWNTHHHPENVEEAVDKSLADLQTDYLDLYLIHWPVAFRYS 117
Query: 467 DS---PDN-----IDYL-----ETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR 607
+ P N ID + +TW M+ + G RSIGVSNF +I L+ + I
Sbjct: 118 TTTIQPVNEQTGLIDVVDVPIKDTWAAMEKLVEKGKVRSIGVSNFTREKIEELLKTAKIT 177
Query: 608 PVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
P +NQIE +P Q L GI V YSP G
Sbjct: 178 PAVNQIEAHPFLQQRDLLEWSTQKGIVVAGYSPLG 212
>UniRef50_A1UEC5 Cluster: 2,5-didehydrogluconate reductase; n=20;
Corynebacterineae|Rep: 2,5-didehydrogluconate reductase
- Mycobacterium sp. (strain KMS)
Length = 283
Score = 139 bits (337), Expect = 6e-32
Identities = 83/209 (39%), Positives = 119/209 (56%)
Frame = +2
Query: 86 AVQAPCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDE 265
A P + L+ G +P + LG G + ++ ++V A+EAGYR IDTAAVY +E
Sbjct: 8 AAGIPSVSLNDGHSIPVLGLGVGELSEAEAE------RSVAAALEAGYRLIDTAAVYGNE 61
Query: 266 EQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHF 445
VG+ + A+G + REE++VTTKL A + SL++LGLDY+DLYLIH+
Sbjct: 62 AAVGRAVN---ASG-IPREEIYVTTKLAVADQGFGTSQDAARASLERLGLDYVDLYLIHW 117
Query: 446 PIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQI 625
P D+ Y+++W G+ A+Q G+ARSIGV NFNA ++ ++ S+ P INQI
Sbjct: 118 PAG-------DHGKYIDSWGGLMKAKQDGVARSIGVCNFNAEHLSNIIDLSFFTPAINQI 170
Query: 626 EVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
E++P Q L GI AY P G
Sbjct: 171 ELHPLLNQAELREVNAGYGIVTEAYGPLG 199
>UniRef50_Q968S3 Cluster: Aldoketoreductase-like protein; n=1;
Orconectes limosus|Rep: Aldoketoreductase-like protein -
Orconectes limosus (Spinycheek crayfish)
Length = 336
Score = 139 bits (337), Expect = 6e-32
Identities = 81/222 (36%), Positives = 113/222 (50%), Gaps = 10/222 (4%)
Frame = +2
Query: 77 AAMAVQAPCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVY 256
A + P I L++G +P + LGTG S V + A+E GYRH D+AA Y
Sbjct: 5 AGAMTKIPTILLNSGSHIPVMGLGTGSLGRNGKMSEEAVTAVLETALECGYRHFDSAAYY 64
Query: 257 QDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYL 436
+E +GQ + I+ G V REELF+TTKL + V LQ+SL L L Y+DLYL
Sbjct: 65 GNEAIIGQVLRRWISEGKVKREELFITTKLPTRGNREKDVARFLQKSLDNLRLPYVDLYL 124
Query: 437 IHFPIATKPDD----SPDNI------DYLETWQGMQDARQLGLARSIGVSNFNATQITRL 586
+H+P D S D + D W+ M+ G ++IG+SNFNA Q+ R+
Sbjct: 125 VHYPCGILDTDRERLSADEVTVDPTTDIHAIWRAMEAQLAAGKTKNIGLSNFNADQVQRI 184
Query: 587 VSNSYIRPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+ +RP + Q+EV+ Q L A C I V A+ P G
Sbjct: 185 IKGCQVRPAVLQVEVHVYMQQGALRAFCAQHDIVVCAFCPLG 226
>UniRef50_Q9HGY0 Cluster: Glycerol dehydrogenase; n=8;
Saccharomycetaceae|Rep: Glycerol dehydrogenase -
Zygosaccharomyces rouxii (Candida mogii)
Length = 310
Score = 138 bits (333), Expect = 2e-31
Identities = 86/223 (38%), Positives = 128/223 (57%), Gaps = 20/223 (8%)
Frame = +2
Query: 104 IQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 283
++L+ G +P V LGT R +K ++ +AV A++AGYRHID AAVY +E +VG+
Sbjct: 11 LKLNTGQTIPQVGLGTWR--SKENEGY----KAVIEALKAGYRHIDGAAVYGNEGEVGK- 63
Query: 284 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPI---- 451
AI + V R E+F+TTKLW Q AL +SL++LGLDY+ LYL+H+P+
Sbjct: 64 ---AIQDSGVPRNEIFLTTKLWCTHQRNPQ--EALDQSLQRLGLDYVGLYLVHWPVPLRT 118
Query: 452 -----------ATKPDDSPD---NIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLV 589
A KPD S D ++++TW+ MQ + G ++IGVSNF+ + L+
Sbjct: 119 ENIKDGNLFQFAEKPDGSKDVDLEWNFIKTWELMQKLLESGKTKAIGVSNFSVNNLKDLL 178
Query: 590 S--NSYIRPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+ + + P +NQ+E +P QE L +C GI + AYSP G
Sbjct: 179 AAPTTKVTPAVNQVEFHPLLPQEELIQYCSEKGIVIEAYSPLG 221
>UniRef50_Q4JX70 Cluster: Putative oxidoreductase; n=1;
Corynebacterium jeikeium K411|Rep: Putative
oxidoreductase - Corynebacterium jeikeium (strain K411)
Length = 285
Score = 137 bits (332), Expect = 2e-31
Identities = 81/205 (39%), Positives = 114/205 (55%)
Frame = +2
Query: 98 PCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 277
P ++++ G P + LG + D+ VR A IE GYRHIDTAA+Y +EE VG
Sbjct: 9 PTLEMNDGKTTPQLGLGVWQ--LSDEDTYTSVRAA----IETGYRHIDTAAIYGNEEAVG 62
Query: 278 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 457
+ +A+A+ G V REELF+TTKLWN A + A ES KKLG+DY+DLYL+H+P
Sbjct: 63 RAVADAVKAGDVQREELFITTKLWNADQACGK--EAFAESQKKLGMDYVDLYLLHWP--- 117
Query: 458 KPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNP 637
P +++ + M + +Q G A SIGV NF + L + P +NQIE++P
Sbjct: 118 ----CPQADSFVQAYDSMAEIQQSGGATSIGVCNFYPEALDALKQAGH-TPAVNQIEIHP 172
Query: 638 TNTQEPLXAHCXSLGIAVMAYSPFG 712
+Q + GI A+SP G
Sbjct: 173 GFSQAEQRSDNRDRGIVTEAWSPLG 197
>UniRef50_Q28P63 Cluster: Aldo/keto reductase; n=4;
Rhodobacteraceae|Rep: Aldo/keto reductase - Jannaschia
sp. (strain CCS1)
Length = 276
Score = 137 bits (332), Expect = 2e-31
Identities = 80/205 (39%), Positives = 118/205 (57%)
Frame = +2
Query: 98 PCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 277
P I+ H G +P V G G + I + V AIE GYR ID A +Y +E +G
Sbjct: 5 PVIKFHDGAQIPQV----GFGIWQVPQDIAG--ETVRSAIEIGYRMIDGAYLYMNEAGLG 58
Query: 278 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 457
+G+ A+GL R+E+FVTTK+WN++ + +++ SLK +G++ +DL LIH+P+
Sbjct: 59 EGLR---ASGL-PRDEVFVTTKVWNNEQGAAKARASVERSLKTIGVEQLDLVLIHWPV-- 112
Query: 458 KPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNP 637
P YLETW+ QD R GL RSIG SNFNA + R+++ + PV+NQIE+NP
Sbjct: 113 -----PSQDLYLETWKAFQDMRDEGLMRSIGTSNFNADHLERIIAETGEAPVLNQIELNP 167
Query: 638 TNTQEPLXAHCXSLGIAVMAYSPFG 712
Q + A + G+ A++P G
Sbjct: 168 MLQQPEMRAVHKAHGVVTQAWTPLG 192
>UniRef50_P38715 Cluster: NADPH-dependent aldose reductase GRE3;
n=39; cellular organisms|Rep: NADPH-dependent aldose
reductase GRE3 - Saccharomyces cerevisiae (Baker's
yeast)
Length = 327
Score = 137 bits (332), Expect = 2e-31
Identities = 86/224 (38%), Positives = 126/224 (56%), Gaps = 21/224 (9%)
Frame = +2
Query: 104 IQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 283
+ L+ G +P V LG + K + +Y AI+ GYR D A Y +E++VG+G
Sbjct: 5 VTLNNGLKMPLVGLGCWKIDKKVCAN------QIYEAIKLGYRLFDGACDYGNEKEVGEG 58
Query: 284 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA--- 454
I +AI+ GLV+R+++FV +KLWN+ H D V AL+++L +GLDY+DLY IHFPIA
Sbjct: 59 IRKAISEGLVSRKDIFVVSKLWNNFHHPDHVKLALKKTLSDMGLDYLDLYYIHFPIAFKY 118
Query: 455 ------------TKPDD------SPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQIT 580
T DD + ++ ++T++ +++ GL +SIGVSNF + I
Sbjct: 119 VPFEEKYPPGFYTGADDEKKGHITEAHVPIIDTYRALEECVDEGLIKSIGVSNFQGSLIQ 178
Query: 581 RLVSNSYIRPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
L+ I+PV QIE +P TQE L C I V+AYS FG
Sbjct: 179 DLLRGCRIKPVALQIEHHPYLTQEHLVEFCKLHDIQVVAYSSFG 222
>UniRef50_Q17G72 Cluster: Aldo-keto reductase; n=9;
Endopterygota|Rep: Aldo-keto reductase - Aedes aegypti
(Yellowfever mosquito)
Length = 316
Score = 136 bits (330), Expect = 4e-31
Identities = 83/198 (41%), Positives = 111/198 (56%), Gaps = 11/198 (5%)
Frame = +2
Query: 152 GRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELF 331
G GT + SD V +A+ A+EAGYRHIDTA VY +E+ +G+ + E + G VTR+ELF
Sbjct: 19 GFGTWRASDE--EVEKALNEALEAGYRHIDTAPVYLNEKTIGKVLKEWMDAGKVTRDELF 76
Query: 332 VTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSP----DNIDYLET 499
+ TKL V L+ SL L L+Y+DLY +H P D P D + LET
Sbjct: 77 IVTKLPPHGTRASTVEKFLKNSLDDLQLEYVDLYHVHVPFTVPEVDGPFLVEDGLIVLET 136
Query: 500 -------WQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEPL 658
W+ M++ + GLAR+IG+SNFN QI R++ N I+P QIE + Q L
Sbjct: 137 TTDHVALWKAMEEVYEAGLARNIGLSNFNQRQIQRILDNCQIKPANLQIENHIYLQQPEL 196
Query: 659 XAHCXSLGIAVMAYSPFG 712
C + GI V AYSP G
Sbjct: 197 VKFCKANGITVTAYSPLG 214
>UniRef50_Q6CFG7 Cluster: Yarrowia lipolytica chromosome B of strain
CLIB122 of Yarrowia lipolytica; n=9; Ascomycota|Rep:
Yarrowia lipolytica chromosome B of strain CLIB122 of
Yarrowia lipolytica - Yarrowia lipolytica (Candida
lipolytica)
Length = 337
Score = 136 bits (330), Expect = 4e-31
Identities = 85/218 (38%), Positives = 124/218 (56%), Gaps = 15/218 (6%)
Frame = +2
Query: 110 LHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAI-EAGYRHIDTAAVYQDEEQVGQGI 286
L+ G +P + LGT + T + V AV A+ E GYRHIDTA Y++E+ VG GI
Sbjct: 36 LNNGKTIPAIGLGTWKSTTEE------VAGAVECALTEGGYRHIDTAFNYRNEDAVGLGI 89
Query: 287 AEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPD 466
A+ G V RE++FVTTK+W H D+V L SL++LGLDY+D+ LIH+P+ P+
Sbjct: 90 KRAMEKG-VKREDIFVTTKIWVTYH--DRVEENLDMSLERLGLDYVDMLLIHWPVPLNPN 146
Query: 467 DS-------PD---NIDYL----ETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI 604
+ PD +ID +TW+ M+ + G +SIGVSNF+ + L+ + +
Sbjct: 147 GNDPVYPLRPDGSRDIDESGSQPKTWKQMEAVLKTGKTKSIGVSNFSIPYLEELLKEAEV 206
Query: 605 RPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFGFV 718
P +NQ+E++P Q L C I + A+SPFG V
Sbjct: 207 VPAVNQVELHPLLPQLELMEFCKKNNIVMTAFSPFGSV 244
>UniRef50_Q1IN88 Cluster: Aldehyde reductase; n=5; Bacteria|Rep:
Aldehyde reductase - Acidobacteria bacterium (strain
Ellin345)
Length = 313
Score = 136 bits (329), Expect = 5e-31
Identities = 78/216 (36%), Positives = 117/216 (54%), Gaps = 13/216 (6%)
Frame = +2
Query: 104 IQLHAGXP-LPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQ 280
I LH G +P ALG G A + +I R A + AG+RH D A Y++E +VG+
Sbjct: 11 IPLHHGAGHIP--ALGFGTLIADPALTITATRDA----LAAGFRHFDCAERYRNEREVGE 64
Query: 281 GIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 460
+ A G + REE+FVTTKLWN H ++V PA + SL +LGLDY+DLYLIH P A +
Sbjct: 65 ALRAGRAAGNIAREEIFVTTKLWNTNHRPERVEPAFEASLDRLGLDYLDLYLIHTPFAFQ 124
Query: 461 PDDSPD------------NIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI 604
P D D + ETW +++ G R+IG+S+ + ++ + + I
Sbjct: 125 PGDEQDPRDQNGSVIYDEGVTLRETWSALENLVDRGRCRAIGLSDISMDRLAPIYEAARI 184
Query: 605 RPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+P + Q+E +P + L C GI ++A++P G
Sbjct: 185 KPAVVQVESHPYLPETELLEFCKRNGIVLLAFAPLG 220
>UniRef50_A6RKL9 Cluster: Putative uncharacterized protein; n=3;
Sclerotiniaceae|Rep: Putative uncharacterized protein -
Botryotinia fuckeliana B05.10
Length = 360
Score = 136 bits (329), Expect = 5e-31
Identities = 77/188 (40%), Positives = 114/188 (60%), Gaps = 1/188 (0%)
Frame = +2
Query: 152 GRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELF 331
G GT S +AV +AIE GYR ID AAVY +E VG+GI E + + RE+++
Sbjct: 43 GFGTWNLKVSPENTTEAVAYAIEIGYRQIDCAAVYGNEVAVGRGIEEGLKRAGLKREDIW 102
Query: 332 VTTKLWNDKH-ARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQG 508
VT+KLWND H + + V L ++L+ LGL+Y+DLYLIH+PI + N+D+++T++
Sbjct: 103 VTSKLWNDHHGSYENVEKGLNQTLQDLGLEYLDLYLIHWPIGFS-SNGAKNLDHVQTYKS 161
Query: 509 MQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEPLXAHCXSLGIA 688
M + +IGVSNF+ Q+ +VS I P ++Q+E++P Q A +LGI
Sbjct: 162 MISLPK-SRVLNIGVSNFSPLQLKNVVSTGTI-PYMHQMELHPYLQQSAWVATHKALGIK 219
Query: 689 VMAYSPFG 712
+ AYSP G
Sbjct: 220 MTAYSPLG 227
>UniRef50_A6WDZ5 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:
Aldo/keto reductase - Kineococcus radiotolerans SRS30216
Length = 343
Score = 136 bits (328), Expect = 7e-31
Identities = 80/217 (36%), Positives = 118/217 (54%), Gaps = 12/217 (5%)
Frame = +2
Query: 98 PCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 277
P +L G +P + +GT G+ + S + V AV A+ AGYR +D AAVY +E QVG
Sbjct: 14 PRRELRGGATVPAIGIGTF-GSDRYSPA--EVAAAVAGAVAAGYRLVDCAAVYGNEAQVG 70
Query: 278 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPI-- 451
+ +A A+A G V R+ELFV +K+WND HA V ++ SL+ L LD++D +H+P
Sbjct: 71 EALAGAVAGG-VDRDELFVVSKVWNDAHAPADAVASVHRSLRDLRLDHLDAVFVHWPFPN 129
Query: 452 ---------ATKPDDSP-DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSY 601
A P P D+ YL W ++ GL R +G SN ++ L+ ++
Sbjct: 130 HHPPMADTDARDPRARPYDHDAYLALWGALEGLVDSGLVRHLGTSNTTVAKLDLLLRDAR 189
Query: 602 IRPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
I P +N++E++P Q L AHC GI + YSP G
Sbjct: 190 IPPALNEMELHPCFQQPELFAHCVRHGIQPVGYSPLG 226
>UniRef50_A2FPE2 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=3; Trichomonas vaginalis G3|Rep:
Oxidoreductase, aldo/keto reductase family protein -
Trichomonas vaginalis G3
Length = 309
Score = 136 bits (328), Expect = 7e-31
Identities = 76/209 (36%), Positives = 126/209 (60%), Gaps = 16/209 (7%)
Frame = +2
Query: 152 GRGTAKXSDSIXXVRQAVYWAIE-AGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREEL 328
G GT D ++ AV+ AIE +GYRH+D AA Y+++E +G+ ++E A G V REE+
Sbjct: 8 GLGTFLAEDP-AALKAAVHSAIEDSGYRHVDCAAYYKNQEIIGEALSEIFAKGQVKREEV 66
Query: 329 FVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA--TKPDDS---------- 472
++T+K+WN KH D +V ++++LK+L L+Y+DL L+H+ A ++ DD
Sbjct: 67 WITSKVWNTKHRPDLLVKDVKKTLKELKLEYLDLVLVHWACAFQSREDDEYLPRDETGKI 126
Query: 473 -PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNS--YIRPVINQIEVNPTN 643
+NID LETW+ M++ LGLA+ IGVSNF+ Q+ R+ + I+P NQ+E +
Sbjct: 127 ITENIDILETWKAMEECYNLGLAKHIGVSNFSIEQLERMRYDPGVKIQPYCNQVESHMYL 186
Query: 644 TQEPLXAHCXSLGIAVMAYSPFGFVVSRG 730
Q+P+ + + +++Y+ G +G
Sbjct: 187 QQQPMLDYLTQRKMYMISYTCLGRATLKG 215
>UniRef50_Q9ZBW7 Cluster: Putative oxidoreductase; n=2;
Actinomycetales|Rep: Putative oxidoreductase -
Streptomyces coelicolor
Length = 277
Score = 135 bits (327), Expect = 9e-31
Identities = 85/210 (40%), Positives = 117/210 (55%)
Frame = +2
Query: 83 MAVQAPCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQD 262
M+ + P I L+ G +P LG G D+ + AV A+EAGYR IDTAA+Y +
Sbjct: 1 MSSKVPPIILNNGVEMPQ--LGFGVWQVPDDDA----QTAVALALEAGYRSIDTAAIYGN 54
Query: 263 EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIH 442
EE G+ IA A+GL RE+LFVTTKLWN D + A S+ KLGL+Y+DLYLIH
Sbjct: 55 EEGTGRAIA---ASGLA-REDLFVTTKLWNSDQGYDSTLRAFDTSMAKLGLEYLDLYLIH 110
Query: 443 FPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQ 622
+P+ K Y++T++ + G R+IGVSNF + RL + + + P +NQ
Sbjct: 111 WPMPAKE-------RYVDTYKAFEKLLADGRVRAIGVSNFLPEHLERLTAETSVIPAVNQ 163
Query: 623 IEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
IE++P Q GIA A+SP G
Sbjct: 164 IELHPHLQQHAAREVHAEQGIATEAWSPLG 193
>UniRef50_A0JRJ3 Cluster: 2,5-didehydrogluconate reductase; n=3;
Actinobacteria (class)|Rep: 2,5-didehydrogluconate
reductase - Arthrobacter sp. (strain FB24)
Length = 276
Score = 135 bits (326), Expect = 1e-30
Identities = 83/206 (40%), Positives = 117/206 (56%)
Frame = +2
Query: 95 APCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQV 274
+P I+L+ G +P + LGT D V AV A+E GYRHIDTA Y +E+ V
Sbjct: 4 SPVIELNDGHRIPQIGLGTW----PLDDH--QVAAAVVNAVEGGYRHIDTAVKYGNEKGV 57
Query: 275 GQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA 454
G GI ++GL R ELF+TTKL + +D+ V L SLK+LGLDY+DL LIH+P+
Sbjct: 58 GNGIR---SSGL-DRSELFITTKLDGEFQGQDRAVAGLDGSLKRLGLDYVDLLLIHWPL- 112
Query: 455 TKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVN 634
P +++ TW+ + + G RSIGVSNF + RL++ + P +NQI+V+
Sbjct: 113 ------PRRDEFISTWKTFERLQADGKVRSIGVSNFKPAHLERLMAACDVVPAVNQIQVS 166
Query: 635 PTNTQEPLXAHCXSLGIAVMAYSPFG 712
P T+ A+ GI +YSP G
Sbjct: 167 PAITRIVDIAYNRRHGIVTESYSPLG 192
>UniRef50_Q2V420 Cluster: Uncharacterized protein At2g37770.1; n=1;
Arabidopsis thaliana|Rep: Uncharacterized protein
At2g37770.1 - Arabidopsis thaliana (Mouse-ear cress)
Length = 283
Score = 135 bits (326), Expect = 1e-30
Identities = 76/207 (36%), Positives = 113/207 (54%), Gaps = 6/207 (2%)
Frame = +2
Query: 83 MAVQAPCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQD 262
MA +L+ G P V LGT + S V AV A++ GYRHID A +Y +
Sbjct: 1 MANAITFFKLNTGAKFPSVGLGTWQA------SPGLVGDAVAAAVKIGYRHIDCAQIYGN 54
Query: 263 EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIH 442
E+++G + + + +V RE+LF+T+KLW H V AL +LK L L+Y+DLYLIH
Sbjct: 55 EKEIGAVLKKLFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIH 114
Query: 443 FPIATKPDD---SPDN---IDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI 604
+P K P+N +D TW+ M+ G AR+IGVSNF+ ++ L+ + +
Sbjct: 115 WPARIKKGSVGIKPENLLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELARV 174
Query: 605 RPVINQIEVNPTNTQEPLXAHCXSLGI 685
P +NQ+E +P+ Q L C S G+
Sbjct: 175 PPAVNQVECHPSWRQTKLQEFCKSKGV 201
>UniRef50_Q8J0K1 Cluster: 4-dihydromethyltrisporate dehydrogenase;
n=2; Parasitella parasitica|Rep:
4-dihydromethyltrisporate dehydrogenase - Parasitella
parasitica
Length = 321
Score = 135 bits (326), Expect = 1e-30
Identities = 81/187 (43%), Positives = 103/187 (55%), Gaps = 17/187 (9%)
Frame = +2
Query: 203 VYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVP 382
+Y AI+ GYR D A Y +E +VG+GI +AI GLV REELF+ TKLWN H++ V
Sbjct: 34 IYQAIKIGYRLFDGACDYGNEVEVGRGINKAIKEGLVKREELFIVTKLWNTFHSKQHVRT 93
Query: 383 ALQESLKKLGLDYIDLYLIHFPIATK---------PDDSPDNIDYL--------ETWQGM 511
A LK GL+Y DLYLIHFPI + P+ + D L E W M
Sbjct: 94 AFDRQLKDWGLEYFDLYLIHFPIPLQYVDPAVSYPPEWYVPHADKLNFERSPIHECWAEM 153
Query: 512 QDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEPLXAHCXSLGIAV 691
+ Q L R+IGV+NFN I L+S + I+P + QIE++P QE L GI V
Sbjct: 154 EKLVQAKLTRNIGVANFNCQAILDLLSYAKIKPAVLQIEIHPLLPQERLVKWVQEQGIQV 213
Query: 692 MAYSPFG 712
AYS FG
Sbjct: 214 TAYSSFG 220
>UniRef50_UPI000023D0F1 Cluster: hypothetical protein FG03517.1;
n=1; Gibberella zeae PH-1|Rep: hypothetical protein
FG03517.1 - Gibberella zeae PH-1
Length = 364
Score = 134 bits (324), Expect = 2e-30
Identities = 67/171 (39%), Positives = 110/171 (64%), Gaps = 2/171 (1%)
Frame = +2
Query: 200 AVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVV 379
AV +A++ GYRHIDTA ++++E++VG+GI A+G V+R+E++VT KLWN H + V
Sbjct: 78 AVEYALKGGYRHIDTALIWRNEDEVGKGIK---ASG-VSRDEIWVTGKLWNTDHRPELVR 133
Query: 380 PALQESLKKLGLDYIDLYLIHFPIATKPD--DSPDNIDYLETWQGMQDARQLGLARSIGV 553
A++ S+ LG++Y+DLYLIH+P+A P+ D +N ++TW+ M++ + GL R+IG
Sbjct: 134 KAIETSIANLGVEYLDLYLIHYPVAWVPETRDVDNNTSLIDTWKAMEELVRAGLTRNIGF 193
Query: 554 SNFNATQITRLVSNSYIRPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSP 706
SNF I +++ + I+P ++ E +P Q+ I V+A SP
Sbjct: 194 SNFAPKDINKILKIASIQPYAHEFETHPYLQQQSFVDFHKKENIKVIAASP 244
>UniRef50_A7CUW0 Cluster: 2,5-didehydrogluconate reductase; n=6;
Bacteria|Rep: 2,5-didehydrogluconate reductase -
Opitutaceae bacterium TAV2
Length = 334
Score = 134 bits (324), Expect = 2e-30
Identities = 82/205 (40%), Positives = 114/205 (55%)
Frame = +2
Query: 98 PCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 277
P + L G +P + LG + D QA A AGYR IDTA +Y +EE VG
Sbjct: 60 PTLPLSDGTSIPQLGLGVWQ---MPDDGAGVPIQA---AFNAGYRAIDTAPIYGNEEGVG 113
Query: 278 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 457
+ I A+GL R+EL++TTK+WN D + A++ESL +L L+Y+DLYLIH+P+
Sbjct: 114 RAIR---ASGL-PRKELYITTKVWNSAQGYDSTLRAVRESLGRLQLEYVDLYLIHWPV-- 167
Query: 458 KPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNP 637
P Y++TW+ + + GLARSIGVSNF + RL + I PV+NQ+E++P
Sbjct: 168 -----PKIDRYVDTWKALAKIKADGLARSIGVSNFTPVYLQRLFDETGIVPVVNQVELHP 222
Query: 638 TNTQEPLXAHCXSLGIAVMAYSPFG 712
Q L A I A+SP G
Sbjct: 223 RLQQHELRAFHAKHRIVTEAWSPLG 247
>UniRef50_Q7PM68 Cluster: ENSANGP00000014386; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000014386 - Anopheles gambiae
str. PEST
Length = 310
Score = 134 bits (324), Expect = 2e-30
Identities = 80/216 (37%), Positives = 114/216 (52%), Gaps = 12/216 (5%)
Frame = +2
Query: 101 CIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQ 280
CI L + +G G + +D ++A+ AI+ GYR DTA Y +E VG+
Sbjct: 6 CINLSDQHSIALPTIGLGTYSILGADG----KEAIRTAIDVGYRMFDTAVAYGNEAIVGE 61
Query: 281 GIAEAIAN-GLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA- 454
I E I +TR++ F+ +KL H +D V + +L +LG+DY+DLYL+H P+A
Sbjct: 62 AIREKIRECNNLTRDDFFIISKLSGSYHRQDLVEKCCRMTLDRLGMDYVDLYLMHTPVAL 121
Query: 455 ----------TKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI 604
TK + D+I E W G++ Q GL RSIGVSNFN QI L+S++ I
Sbjct: 122 QSEKKCARNGTKLNAIDDSIAPTEAWIGLEQCYQEGLCRSIGVSNFNEHQINALLSDASI 181
Query: 605 RPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
P +NQIE + Q P+ C I VM Y+P G
Sbjct: 182 VPAVNQIECSIGFNQRPMRKFCQQQNILVMGYTPLG 217
>UniRef50_Q68ST9 Cluster: Reductase AKOR2; n=2; Pleurotus
djamor|Rep: Reductase AKOR2 - Pleurotus djamor
Length = 306
Score = 134 bits (324), Expect = 2e-30
Identities = 83/220 (37%), Positives = 122/220 (55%), Gaps = 14/220 (6%)
Frame = +2
Query: 98 PCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 277
P I L+ G +P +ALG G + + ++ A+++GYRHIDTA +Y E+ VG
Sbjct: 5 PPIVLNTGARMPALALGGWAGLTE--EERTQAKEWFLTALKSGYRHIDTAQIYYTEKSVG 62
Query: 278 QGIAEAIANGLVTREELFVTTKL-WNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA 454
I E+ G + REELF+TTKL WN H+R V + Q+SL+ LG +YIDLYL+HFP
Sbjct: 63 NAIRES---G-IPREELFITTKLPWNH-HSR--VAESFQKSLENLGTEYIDLYLVHFPQR 115
Query: 455 TKPD---DSPDNID----------YLETWQGMQDARQLGLARSIGVSNFNATQITRLVSN 595
D D P N D + W ++ G ++IGVSN++ + L+
Sbjct: 116 VFYDETTDFPRNPDGSIKVVNSPTLNDVWADVETLLDTGKVKAIGVSNYSIKTLEELLKT 175
Query: 596 SYIRPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFGF 715
+ + P +NQ+E++P Q L A+C GIAV AY+P G+
Sbjct: 176 AKVVPAVNQVELHPFLAQSKLLAYCKEKGIAVTAYTPTGY 215
>UniRef50_A6ESC0 Cluster: ARA1; n=1; unidentified eubacterium
SCB49|Rep: ARA1 - unidentified eubacterium SCB49
Length = 280
Score = 133 bits (322), Expect = 4e-30
Identities = 69/187 (36%), Positives = 110/187 (58%)
Frame = +2
Query: 152 GRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELF 331
G GT + D + A+ AI+AGY+HID AA+Y++E+ VG GI EA + R++LF
Sbjct: 17 GFGTWQTPDGQTAIN-AIKTAIDAGYKHIDAAAIYKNEKGVGLGIKEAN----IDRKDLF 71
Query: 332 VTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGM 511
VT+K+WN++ + + A ++ L LDY+DLYLIH+P A ++ ++ +TW M
Sbjct: 72 VTSKVWNEQRGYENTLKAFDNTINDLQLDYLDLYLIHWPAAAHQFENWKQLNN-DTWSAM 130
Query: 512 QDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEPLXAHCXSLGIAV 691
+ + G +++GVSNF +T L+ ++ I+P +NQIE +P Q+ C I V
Sbjct: 131 EKLYKDGKIKALGVSNFMEHHLTPLLQHATIKPTVNQIEYHPGYMQQDCVQFCNDNNIQV 190
Query: 692 MAYSPFG 712
+SP G
Sbjct: 191 EGWSPLG 197
>UniRef50_A0JRJ6 Cluster: Aldo/keto reductase; n=2;
Micrococcineae|Rep: Aldo/keto reductase - Arthrobacter
sp. (strain FB24)
Length = 281
Score = 133 bits (321), Expect = 5e-30
Identities = 80/205 (39%), Positives = 115/205 (56%)
Frame = +2
Query: 98 PCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 277
P + L+ G +P + G + + + I V A+EAGYRHIDTAA Y++E VG
Sbjct: 10 PQLTLNNGVKIPQLGFGVFQVPPEETQRI------VEDALEAGYRHIDTAAAYRNEAGVG 63
Query: 278 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 457
I+ A+G + RE++F+TTKL N + A Q S K LG++++DLYLIH+P+
Sbjct: 64 AAIS---ASG-IPREDIFITTKLRNGEQGNAH--EAFQNSRKALGVEFVDLYLIHWPV-- 115
Query: 458 KPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNP 637
P Y E W+ M+ R+IGVSNF + L+ + + P +NQ+E++P
Sbjct: 116 -----PSQGLYTEAWKAMEKLYANSQIRAIGVSNFLGEHLDTLLPAADVVPAVNQVEIHP 170
Query: 638 TNTQEPLXAHCXSLGIAVMAYSPFG 712
T Q+ L A C LGIAV AYSP G
Sbjct: 171 TFQQQELAAKCRELGIAVEAYSPLG 195
>UniRef50_Q235V6 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=2; Tetrahymena thermophila SB210|Rep:
Oxidoreductase, aldo/keto reductase family protein -
Tetrahymena thermophila SB210
Length = 332
Score = 133 bits (321), Expect = 5e-30
Identities = 72/201 (35%), Positives = 119/201 (59%), Gaps = 1/201 (0%)
Frame = +2
Query: 107 QLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGI 286
+L+ G +P V LGT +K + + A++AGYRHIDTA YQ+E +G+ +
Sbjct: 9 KLNNGQIMPLVGLGTYLLNSKEE-----MTNLLRTALDAGYRHIDTAVNYQNEAMIGESL 63
Query: 287 AEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPD 466
G +R++LF+ +K++ +K ++ ++++SLK+L LDY+DLY +HFP+ +
Sbjct: 64 KTIFKEGKYSRKDLFIVSKVFPNKGIN--MLESVKKSLKELQLDYVDLYYLHFPLGFLSE 121
Query: 467 DSPD-NIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTN 643
++ W +++A +LGLA+SIGVSNFN + L+S + ++PV NQ+EV+
Sbjct: 122 KEEFVHLPVHVAWAQLEEAHRLGLAKSIGVSNFNVMALADLLSYAKVKPVSNQVEVSVFI 181
Query: 644 TQEPLXAHCXSLGIAVMAYSP 706
Q+ L C GI V AY+P
Sbjct: 182 QQKNLIKFCQRFGIHVTAYAP 202
>UniRef50_Q1VRG6 Cluster: YvgN; n=1; Psychroflexus torquis ATCC
700755|Rep: YvgN - Psychroflexus torquis ATCC 700755
Length = 280
Score = 132 bits (320), Expect = 7e-30
Identities = 82/201 (40%), Positives = 114/201 (56%), Gaps = 2/201 (0%)
Frame = +2
Query: 110 LHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 289
L+ G +P V GT + A + I ++++ A+ GYR IDT A+YQ+EE VG+ I
Sbjct: 5 LNDGNRIPIVGFGTYK--ANEEEGIKSIQKS---ALTLGYRLIDTVAIYQNEEAVGKAIK 59
Query: 290 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFP--IATKP 463
A G V REE+FVTTKLW + Q AL ESL+KL L+YIDLYLIH+P
Sbjct: 60 ---ARG-VLREEIFVTTKLWRENLGYKQTRIALDESLRKLDLNYIDLYLIHWPANAINYK 115
Query: 464 DDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTN 643
D N D TW+ M++ + G +S+GVSNF + L + + P +NQIE +P
Sbjct: 116 DWQKTNAD---TWRAMEELQAEGKIKSLGVSNFWPEHLEALFQTAKVSPSVNQIEFHPGY 172
Query: 644 TQEPLXAHCXSLGIAVMAYSP 706
Q + C + GIAV ++SP
Sbjct: 173 WQPQVTEFCKNHGIAVESWSP 193
>UniRef50_Q9U2J5 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 339
Score = 132 bits (320), Expect = 7e-30
Identities = 73/218 (33%), Positives = 122/218 (55%), Gaps = 16/218 (7%)
Frame = +2
Query: 95 APCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQV 274
A + L++G +P + G GT + ++ R V A+EAGYRHID+A ++++E+V
Sbjct: 4 ADTVTLNSGYEMPVI----GYGTWQLPKNLAAER--VRDALEAGYRHIDSALSFKNQEEV 57
Query: 275 GQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA 454
GI + V REELF+++K+WN H+R++ + + E L+ Y+DL +IH+P
Sbjct: 58 AAGIKDWCKIRKVRREELFLSSKIWNTYHSRNRCMQQIDEMLEIFETTYMDLIVIHWPFG 117
Query: 455 TKPDDSP----------------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRL 586
D+ P ++DYLETW+ ++DA + G RSIG++NFN Q+ ++
Sbjct: 118 WAEDEPPGERGLWPRGANGKMRYSDVDYLETWKALEDAHRSGKIRSIGLANFNIGQVEQV 177
Query: 587 VSNSYIRPVINQIEVNPTNTQEPLXAHCXSLGIAVMAY 700
+ I+P + Q+E+NP QE + C GI + A+
Sbjct: 178 WTKGLIKPAVLQVEMNPFLDQEEIRQFCREKGIILTAF 215
>UniRef50_Q927P9 Cluster: Lin2739 protein; n=12; Bacteria|Rep:
Lin2739 protein - Listeria innocua
Length = 283
Score = 132 bits (319), Expect = 9e-30
Identities = 82/202 (40%), Positives = 115/202 (56%)
Frame = +2
Query: 104 IQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 283
++L+ G +P + G GT + +D+ QAV AI AGYRHIDTA Y +EE VG+G
Sbjct: 4 VKLNNGIEVPIL----GFGTYQITDA-GEAEQAVKEAIAAGYRHIDTAQSYMNEEAVGRG 58
Query: 284 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 463
IA A+G V R+ELF+TTK+W + + V+ + SLK+LGLDYIDL LIH P
Sbjct: 59 IA---ASG-VDRKELFITTKIWVENVSYKGVMSSFDRSLKRLGLDYIDLLLIHQPYN--- 111
Query: 464 DDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTN 643
D W M++ + G ++IGVSNF ++ L + + I P +NQIE+NP
Sbjct: 112 -------DVYGAWMAMEELQAQGKIKAIGVSNFGVDRVVDLAAFNDITPQVNQIEINPFQ 164
Query: 644 TQEPLXAHCXSLGIAVMAYSPF 709
Q G+AV A++PF
Sbjct: 165 QQSKNIEALRKEGVAVEAWAPF 186
>UniRef50_Q8Y463 Cluster: Lmo2592 protein; n=40; Bacteria|Rep:
Lmo2592 protein - Listeria monocytogenes
Length = 283
Score = 132 bits (318), Expect = 1e-29
Identities = 81/202 (40%), Positives = 117/202 (57%)
Frame = +2
Query: 104 IQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 283
++L+ G +P + G GT + +D+ AV AI+AGYRHIDTA Y +EE VG+G
Sbjct: 4 VKLNNGVEVPIL----GFGTYQITDA-AEAEHAVKDAIKAGYRHIDTAQSYMNEEAVGRG 58
Query: 284 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 463
IA A+G V R+ELF+TTK+W + + V+ + SLK+LGLDY+DL LIH P
Sbjct: 59 IA---ASG-VDRKELFITTKIWVENVSYKGVMSSFDRSLKRLGLDYVDLLLIHQPFN--- 111
Query: 464 DDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTN 643
D W M++ + G R+IGVSNF+ ++ L + + + P +NQIEVNP
Sbjct: 112 -------DVYGAWIAMEELQASGKIRAIGVSNFSPDRVIDLAAFNEVTPQVNQIEVNPFQ 164
Query: 644 TQEPLXAHCXSLGIAVMAYSPF 709
Q A G+A+ A++PF
Sbjct: 165 QQTANLAILRKEGVAIEAWAPF 186
>UniRef50_A6W8E7 Cluster: 2,5-didehydrogluconate reductase; n=3;
Actinomycetales|Rep: 2,5-didehydrogluconate reductase -
Kineococcus radiotolerans SRS30216
Length = 289
Score = 132 bits (318), Expect = 1e-29
Identities = 84/207 (40%), Positives = 119/207 (57%)
Frame = +2
Query: 86 AVQAPCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDE 265
A+ P I L+ G +P LG G + D+ QAV A++ GYRHIDTA +Y +E
Sbjct: 9 AMTVPTILLNDGREIPQ--LGFGVFQIEPGDTA----QAVKTALDLGYRHIDTAQMYGNE 62
Query: 266 EQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHF 445
+V QGIA++ G V R+E++VT+KL N H D A+ +S++KL IDLYLIH+
Sbjct: 63 AEVAQGIADS---G-VPRDEIWVTSKLNNGFHEPDAARKAVDDSVEKLR-GPIDLYLIHW 117
Query: 446 PIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQI 625
P+ T D++ TW+ +++AR G RSIGVSNF + RL + + P +NQI
Sbjct: 118 PLPTLYGG-----DFVSTWKVLEEARAAGKLRSIGVSNFQVNHLQRLAQEATVVPAVNQI 172
Query: 626 EVNPTNTQEPLXAHCXSLGIAVMAYSP 706
EV+P E + HC I V A+SP
Sbjct: 173 EVHPYFGNEEVRRHCGEHQIGVEAWSP 199
>UniRef50_Q17DN1 Cluster: Aldo-keto reductase; n=1; Aedes
aegypti|Rep: Aldo-keto reductase - Aedes aegypti
(Yellowfever mosquito)
Length = 284
Score = 132 bits (318), Expect = 1e-29
Identities = 80/210 (38%), Positives = 119/210 (56%)
Frame = +2
Query: 83 MAVQAPCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQD 262
M+ +AP ++L+ G +P + LGT +K + + +A+ AI+AGYRHIDTA YQ+
Sbjct: 1 MSPKAPMVKLNNGLEMPVLGLGTW--LSKEGEGV----EAIKAAIDAGYRHIDTAYFYQN 54
Query: 263 EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIH 442
E++VG+ I I G+V RE+LFVTTK +D+ L+
Sbjct: 55 EKEVGEAIRAKIEEGVVCREDLFVTTKF----------------------IDWDTKNLMP 92
Query: 443 FPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQ 622
+ K S ++DY++TW+ M+ + G +SIGVSNFN+ QITRL++ I+PV NQ
Sbjct: 93 YDADGKLQFS--DVDYIDTWKAMEKLLKTGKVKSIGVSNFNSEQITRLLAECEIKPVTNQ 150
Query: 623 IEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+E NP+ Q L C +L I + AYSP G
Sbjct: 151 VECNPSLNQRKLTEFCKNLDITLTAYSPLG 180
>UniRef50_UPI00015B5BD7 Cluster: PREDICTED: similar to aldo-keto
reductase; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to aldo-keto reductase - Nasonia vitripennis
Length = 310
Score = 131 bits (317), Expect = 2e-29
Identities = 75/218 (34%), Positives = 126/218 (57%), Gaps = 4/218 (1%)
Frame = +2
Query: 71 LHAAMAVQAPCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAA 250
L AA+ ++L+ G +P V +GT + + +++ + + G+R IDTA
Sbjct: 15 LEAALTPTIRDLRLNNGYDMPLVGIGTYKVRGRE-----VIKRVIDESFAVGFRSIDTAV 69
Query: 251 VYQDEEQVGQGIAEAIANGLVTREELFVTTKLW-NDKHARDQVVPALQESLKKLGLDYID 427
VY++EE +G + E + + RE++F+T+KL +D D++ ++++SLK L Y+D
Sbjct: 70 VYRNEEDIGLALKELLPKYNLKREDIFITSKLSPSDNGDPDKIRKSVEDSLKALDTSYLD 129
Query: 428 LYLIHFPIATK-PDDSPDNIDY-LETWQGMQDARQLGLARSIGVSNFNATQITRLVSN-S 598
LYLIH+P A++ ++SPDN + TW + + +Q GL RSIGVSN+ + L+ + S
Sbjct: 130 LYLIHWPGASRILENSPDNPKLRVTTWATLVELQQKGLLRSIGVSNYTVGHLEHLLEHCS 189
Query: 599 YIRPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
++P +NQ+E +P Q+ L C GI V AYS G
Sbjct: 190 GVKPDVNQVECHPHFRQDELIEFCTKQGIHVQAYSSLG 227
>UniRef50_Q83N50 Cluster: 2,5-diketo-D-gluconic acid reductase; n=2;
Tropheryma whipplei|Rep: 2,5-diketo-D-gluconic acid
reductase - Tropheryma whipplei (strain Twist)
(Whipple's bacillus)
Length = 283
Score = 131 bits (317), Expect = 2e-29
Identities = 77/204 (37%), Positives = 113/204 (55%)
Frame = +2
Query: 98 PCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 277
P + L G +P LGT + S+ V AIE GYRHIDTA++Y +E +VG
Sbjct: 10 PSVLLGDGVSIPQFGLGTYELPPNEASSV------VQSAIELGYRHIDTASLYANEREVG 63
Query: 278 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 457
+ AIA+ + REE FVTTKLWN + + A + SL L LDY+DLYLIH+P
Sbjct: 64 R----AIASSGIKREEFFVTTKLWNSDQPKPR--EAFERSLDLLSLDYVDLYLIHWPC-- 115
Query: 458 KPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNP 637
P + Y+ W+ + + ++ G A+S+GVSNF + I ++ + P +NQIE++P
Sbjct: 116 -----PPSELYINVWEVLLELKESGRAKSVGVSNFLSEHIDKIKEAGFPLPSVNQIELHP 170
Query: 638 TNTQEPLXAHCXSLGIAVMAYSPF 709
Q L C + GI + ++ PF
Sbjct: 171 WLQQRELVLSCRNDGIQIESWGPF 194
>UniRef50_UPI00006CD296 Cluster: oxidoreductase, aldo/keto reductase
family protein; n=1; Tetrahymena thermophila SB210|Rep:
oxidoreductase, aldo/keto reductase family protein -
Tetrahymena thermophila SB210
Length = 295
Score = 131 bits (316), Expect = 2e-29
Identities = 74/201 (36%), Positives = 113/201 (56%), Gaps = 1/201 (0%)
Frame = +2
Query: 107 QLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGI 286
+L G LP LGT + +K + + +R A ++ GYRHIDTA +Y++E+Q+G +
Sbjct: 9 ELCNGSKLPVFGLGTYKVVSK-EEMVTFLRTA----LDLGYRHIDTAIMYENEKQIGDAL 63
Query: 287 AEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPD 466
E G RE+LF+ TKL+++K+ + V +++SL+ L +YIDLYL+H+ + D
Sbjct: 64 QEIYKEGKYKREDLFLVTKLFSNKNTK--VEDQVRQSLQNLQTNYIDLYLLHYASSPPTD 121
Query: 467 DSP-DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTN 643
+ + W ++ Q GL R+IG+SNFN + L S I+PV+NQIEVN
Sbjct: 122 QFELTHKPVFQVWAEFEELVQKGLIRNIGISNFNVQMLLDLYSYCKIKPVVNQIEVNVYC 181
Query: 644 TQEPLXAHCXSLGIAVMAYSP 706
Q L C L + V AY P
Sbjct: 182 QQPRLLEFCKKLNLHVTAYCP 202
>UniRef50_Q8G7K9 Cluster: Dehydrogenase or reductase protein; n=4;
Bifidobacterium|Rep: Dehydrogenase or reductase protein
- Bifidobacterium longum
Length = 289
Score = 131 bits (316), Expect = 2e-29
Identities = 82/203 (40%), Positives = 109/203 (53%)
Frame = +2
Query: 98 PCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 277
P I L G +P V LG R D V V A+EAGYRHID AA Y +E VG
Sbjct: 12 PDIALKDGHSIPQVGLGVLR----IDDE--GVVPVVESALEAGYRHIDGAAGYNNEAGVG 65
Query: 278 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 457
+ +A + N RE L+VTTKL + + D + A SLK L LDY+D+Y+IH+P
Sbjct: 66 RALAASGYNKGAKRETLWVTTKLRDSQQGYDSALKAFDNSLKLLQLDYVDMYMIHWP--- 122
Query: 458 KPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNP 637
+P + +TW+ R G+AR++GV NF + RL + P +NQIE++P
Sbjct: 123 ----TPFDWRSTDTWKAFVKLRDEGMARTLGVCNFMPADLKRLHEETGAWPAVNQIELHP 178
Query: 638 TNTQEPLXAHCXSLGIAVMAYSP 706
T Q + A C GIAV AYSP
Sbjct: 179 TWQQREVVAFCKEHGIAVEAYSP 201
>UniRef50_Q4PAT5 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 700
Score = 131 bits (316), Expect = 2e-29
Identities = 82/204 (40%), Positives = 117/204 (57%), Gaps = 17/204 (8%)
Frame = +2
Query: 152 GRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELF 331
G GT K S AV AI+ GYRHID A Y++E+ V GI +A G V R +L+
Sbjct: 24 GFGTWKMSKE--QATPAVAHAIKTGYRHIDCAWAYRNEDAVAAGIKKA---G-VPRSQLW 77
Query: 332 VTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA----------------TKP 463
+T+KLWN H + V AL SLK LG DY+DLYL+H+P+A P
Sbjct: 78 LTSKLWNSFHHPEHVEKALDASLKDLGTDYLDLYLMHWPVAFLNSKGSMVPSIRSTGGHP 137
Query: 464 DDSPD-NIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPT 640
+S D + D++ T++ M++ + G R+IGVSNFN + + +V + I+PV+NQ+EVN
Sbjct: 138 VESEDLSRDFMATYRVMEEMVKKGKVRNIGVSNFNIRRTSEVVDEASIKPVVNQVEVNLG 197
Query: 641 NTQEPLXAHCXSLGIAVMAYSPFG 712
E L + + G+ + AYSPFG
Sbjct: 198 VHNEELRNYAHAHGVTLQAYSPFG 221
>UniRef50_Q568D7 Cluster: Zgc:110366; n=7; Euteleostomi|Rep:
Zgc:110366 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 289
Score = 130 bits (315), Expect = 3e-29
Identities = 75/207 (36%), Positives = 107/207 (51%)
Frame = +2
Query: 86 AVQAPCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDE 265
A+ P + LH G +P + LGT +++ Q E G RHIDTA Y E
Sbjct: 10 ALSCPAVPLHNGLNIPILGLGTSHYGGYSHEAVLYALQ------ECGIRHIDTAKRYGCE 63
Query: 266 EQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHF 445
E +G+ + E+ G V REEL+VTTKLW + A ++S +LG+DY+DLYL+H+
Sbjct: 64 EALGKAVTES---G-VQREELWVTTKLWPGDYGYQSTKQACRDSRARLGVDYLDLYLMHW 119
Query: 446 PIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQI 625
P + P S + LETW+ +++ GL R+IGVSNF + L + I P +NQ+
Sbjct: 120 PDSMVPGRSSQEV-RLETWRALEELYDEGLCRAIGVSNFLIPHLNELKDSGGIVPHVNQV 178
Query: 626 EVNPTNTQEPLXAHCXSLGIAVMAYSP 706
E +P L HC I Y P
Sbjct: 179 EFHPFQQPMKLVEHCRKENIVFEGYCP 205
>UniRef50_Q9X0A2 Cluster: Oxidoreductase, aldo/keto reductase
family; n=21; Bacteria|Rep: Oxidoreductase, aldo/keto
reductase family - Thermotoga maritima
Length = 286
Score = 130 bits (315), Expect = 3e-29
Identities = 79/207 (38%), Positives = 113/207 (54%)
Frame = +2
Query: 89 VQAPCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEE 268
+Q P + L+ G +P + G + + ++ + VY AI+ GYR IDTAA Y +EE
Sbjct: 1 MQVPKVTLNNGVEMPILGYGVFQIPPEKTE------ECVYEAIKVGYRLIDTAASYMNEE 54
Query: 269 QVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFP 448
VG+ I AI G+V REELFVTTKLW + A ++SLKKL L+YIDLYLIH P
Sbjct: 55 GVGRAIKRAIDEGIVRREELFVTTKLWVSDVGYESTKKAFEKSLKKLQLEYIDLYLIHQP 114
Query: 449 IATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIE 628
D W+ M++ + GL R+IGVSNF ++ L+ + I P +NQIE
Sbjct: 115 FG----------DVHCAWKAMEEMYKDGLVRAIGVSNFYPDRLMDLMVHHEIVPAVNQIE 164
Query: 629 VNPTNTQEPLXAHCXSLGIAVMAYSPF 709
++P ++ + I A+ PF
Sbjct: 165 IHPFYQRQEEIEFMRNYNIQPEAWGPF 191
>UniRef50_Q9VHX4 Cluster: CG2767-PA; n=4; Endopterygota|Rep:
CG2767-PA - Drosophila melanogaster (Fruit fly)
Length = 329
Score = 130 bits (315), Expect = 3e-29
Identities = 79/200 (39%), Positives = 109/200 (54%), Gaps = 13/200 (6%)
Frame = +2
Query: 152 GRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELF 331
G GT + SD + A+ A+EAGYRHIDTA VY +E+ +G+ + + G V REELF
Sbjct: 19 GIGTWQASDE--EIETAIDAALEAGYRHIDTAPVYGNEKAIGRVLKRWLDAGKVKREELF 76
Query: 332 VTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK-PDDSPDNID------- 487
+ TK+ + +V P +++SL+ L LDY+DLYL+H P +D +D
Sbjct: 77 IVTKVPPVSNRPHEVEPTIKKSLEDLQLDYVDLYLVHTPFTININEDGSFKLDKEGLMEV 136
Query: 488 -----YLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQE 652
+ W M+ + GL +SIGVSNF+ Q+ RL+ N IRP NQIE + Q
Sbjct: 137 DVTTNHAAIWVAMEALVEKGLTKSIGVSNFSKDQVARLLKNCKIRPANNQIEHHVYLQQR 196
Query: 653 PLXAHCXSLGIAVMAYSPFG 712
L C S I V AYSP G
Sbjct: 197 DLVDFCKSENITVTAYSPLG 216
>UniRef50_UPI0000E45E29 Cluster: PREDICTED: similar to aldose
reductase; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to aldose reductase -
Strongylocentrotus purpuratus
Length = 274
Score = 130 bits (314), Expect = 3e-29
Identities = 70/174 (40%), Positives = 100/174 (57%)
Frame = +2
Query: 191 VRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARD 370
V AV AI+ GYRHID A VY +E +VG G+ E +V RE++F+T+KLWN+KH D
Sbjct: 12 VEAAVKAAIDCGYRHIDCAHVYGNEAEVGAGLKEKFDANVVKREDIFITSKLWNNKHHPD 71
Query: 371 QVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIG 550
V A +LK L L Y+DLYL+H+P+A +Q M+ G ++IG
Sbjct: 72 DVEQACDITLKNLQLSYVDLYLMHWPMA---------------YQAMEKLVTSGKCKAIG 116
Query: 551 VSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+SNF+ + R++ + I+P Q+E++P TQE L C + V AYSP G
Sbjct: 117 LSNFSMKMMKRVIEKATIQPANLQVELHPLLTQEKLIEFCKEHNMTVTAYSPLG 170
>UniRef50_UPI0000499B0E Cluster: oxidoreductase, aldo/keto reductase
family; n=1; Entamoeba histolytica HM-1:IMSS|Rep:
oxidoreductase, aldo/keto reductase family - Entamoeba
histolytica HM-1:IMSS
Length = 307
Score = 130 bits (314), Expect = 3e-29
Identities = 85/209 (40%), Positives = 117/209 (55%), Gaps = 8/209 (3%)
Frame = +2
Query: 110 LHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQ-GI 286
L+ G +P + LGT V +AV A+E GYR ID A Y++E+++G+ GI
Sbjct: 8 LNNGKFMPAIGLGTWLAAP------GEVGKAVTLALENGYRLIDCARFYKNEKEIGEMGI 61
Query: 287 AEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPD 466
+ N REELFVT+KLW D+ R + + ES++ L Y+DLYLIH+PIA K D
Sbjct: 62 EPFLKNH--PREELFVTSKLWMDQVTR--IRESCLESIQDLKCKYLDLYLIHWPIALKVD 117
Query: 467 DS----PDN---IDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQI 625
S P++ +D E WQ M+ GL +SIG+SNF QI +++ I+PVINQ+
Sbjct: 118 ASNPPKPEDFLDMDITEIWQEMERLVDEGLVKSIGLSNFTIPQIEKIMKMCRIKPVINQV 177
Query: 626 EVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
E+N Q L C S I V AY P G
Sbjct: 178 ELNVYLQQNKLREVCKSYNIVVEAYRPIG 206
>UniRef50_Q838E0 Cluster: Oxidoreductase, aldo/keto reductase
family; n=24; Bacilli|Rep: Oxidoreductase, aldo/keto
reductase family - Enterococcus faecalis (Streptococcus
faecalis)
Length = 279
Score = 130 bits (314), Expect = 3e-29
Identities = 76/204 (37%), Positives = 111/204 (54%)
Frame = +2
Query: 95 APCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQV 274
A + L+ G +P G G G + D + V I GYR IDTA +Y +E
Sbjct: 6 ADTVTLNNGTKIP----GMGLGVFQIPDE--ETAKVVEEGIINGYRLIDTAQIYGNESGT 59
Query: 275 GQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA 454
G GI +A + RE+LFVT+K+WN + D+ + A +SL++LGLDY+DLYLIH+
Sbjct: 60 GAGIKAGLAATGLNREDLFVTSKVWNAHISYDETIQAFNDSLERLGLDYLDLYLIHW--- 116
Query: 455 TKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVN 634
P N Y E+WQ ++ G ++IGVSNF + L+S + + PVINQ+E++
Sbjct: 117 ------PGNNSYKESWQALETLYAEGKVKAIGVSNFQVHHLEDLLSYAKVVPVINQVELH 170
Query: 635 PTNTQEPLXAHCXSLGIAVMAYSP 706
P Q+ + C I V A+SP
Sbjct: 171 PKLDQKEVRDFCEKHDIKVQAWSP 194
>UniRef50_A5ZYE6 Cluster: Putative uncharacterized protein; n=1;
Ruminococcus obeum ATCC 29174|Rep: Putative
uncharacterized protein - Ruminococcus obeum ATCC 29174
Length = 263
Score = 130 bits (314), Expect = 3e-29
Identities = 77/185 (41%), Positives = 107/185 (57%)
Frame = +2
Query: 152 GRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELF 331
G G K +D++ A+ A++ GYR +DTA+ Y++EE VG GIA+ G V R++LF
Sbjct: 5 GLGLYKTTDAVEA-EDAIAAAVQNGYRLLDTASAYKNEEFVGCGIAKC---G-VPRKDLF 59
Query: 332 VTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGM 511
+TTK+WN+ V A Q SL +LGLDYIDLYLIH+P+ +L TW+ M
Sbjct: 60 ITTKIWNNAQRLGDVEGAFQRSLDRLGLDYIDLYLIHWPVPG---------CFLNTWKDM 110
Query: 512 QDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEPLXAHCXSLGIAV 691
+ + G A SIGVSNF + L S I P +NQIE +P + L +C + I V
Sbjct: 111 EKILESGRALSIGVSNFEIRHLEELRRVSGIVPAVNQIECHPLCYPKELIEYCQANDIQV 170
Query: 692 MAYSP 706
AY+P
Sbjct: 171 QAYAP 175
>UniRef50_P38115 Cluster: D-arabinose dehydrogenase [NAD(P)+] heavy
chain; n=3; Saccharomycetaceae|Rep: D-arabinose
dehydrogenase [NAD(P)+] heavy chain - Saccharomyces
cerevisiae (Baker's yeast)
Length = 344
Score = 130 bits (314), Expect = 3e-29
Identities = 81/210 (38%), Positives = 114/210 (54%), Gaps = 23/210 (10%)
Frame = +2
Query: 152 GRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELF 331
G GTA + + +QAV AI+AGYRHIDTA Y+ E VG+ I E + +G + RE+LF
Sbjct: 37 GLGTANPHEKLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAIKELLEDGSIKREDLF 96
Query: 332 VTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA---------------TKPD 466
+TTK+W D+V +L ESLK LGL+Y+DL L H+P+ T D
Sbjct: 97 ITTKVW--PVLWDEVDRSLNESLKALGLEYVDLLLQHWPLCFEKIKDPKGISGLVKTPVD 154
Query: 467 DSPDNI-----DYLETWQGMQDAR---QLGLARSIGVSNFNATQITRLVSNSYIRPVINQ 622
DS + DYLET++ ++ R+IGVSNF+ + RL+ ++P +NQ
Sbjct: 155 DSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNFSIEYLERLIKECRVKPTVNQ 214
Query: 623 IEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+E +P Q L C I + AYSP G
Sbjct: 215 VETHPHLPQMELRKFCFMHDILLTAYSPLG 244
>UniRef50_UPI0000D9A956 Cluster: PREDICTED: similar to aldo-keto
reductase family 1, member B10, partial; n=1; Macaca
mulatta|Rep: PREDICTED: similar to aldo-keto reductase
family 1, member B10, partial - Macaca mulatta
Length = 275
Score = 130 bits (313), Expect = 5e-29
Identities = 76/192 (39%), Positives = 110/192 (57%), Gaps = 8/192 (4%)
Frame = +2
Query: 161 TAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTT 340
T K + V++AV AI+AGYRHID A VYQ+E +VG+ I E I V RE+LF+ +
Sbjct: 38 TRKPKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEQAVKREDLFIVS 97
Query: 341 K------LWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETW 502
K LW R V A +++LK L L Y+D+YLIH+P + +
Sbjct: 98 KVHMAHWLWTTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWP---------------QGF 142
Query: 503 QGMQDARQLGLARSIGVSNFNATQITRLVSNSYI--RPVINQIEVNPTNTQEPLXAHCXS 676
+ M++ GL +++G+SNFN QI +L++ + +PV NQ+E +P TQE L +C S
Sbjct: 143 KAMEELVDEGLVKALGISNFNHFQIEKLLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHS 202
Query: 677 LGIAVMAYSPFG 712
GI + AYSP G
Sbjct: 203 KGITITAYSPLG 214
>UniRef50_Q4V008 Cluster: Oxidoreductase; n=4; Proteobacteria|Rep:
Oxidoreductase - Xanthomonas campestris pv. campestris
(strain 8004)
Length = 267
Score = 129 bits (311), Expect = 8e-29
Identities = 84/185 (45%), Positives = 108/185 (58%), Gaps = 2/185 (1%)
Frame = +2
Query: 152 GRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELF 331
G GT + D + V +V A+ GYR IDTA +Y +E QVGQ IA+A G V R++LF
Sbjct: 7 GLGTFRLKDQV--VIDSVRNALALGYRAIDTAQIYDNEAQVGQAIADA---G-VPRDQLF 60
Query: 332 VTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGM 511
VTTK+W D+ +RD + P+LQESL+KLG DY+DL LIH+P P D +YLE +
Sbjct: 61 VTTKIWVDRFSRDTLQPSLQESLRKLGTDYVDLTLIHWP---SPKDQVPMREYLE---AL 114
Query: 512 QDARQLGLARSIGVSNFNATQITRLVSNSYIRPVI--NQIEVNPTNTQEPLXAHCXSLGI 685
DA+ GL R+IGVSNF +TR I NQIEV+P L A GI
Sbjct: 115 ADAKAQGLTRAIGVSNFTIA-LTRQAIEILGADAIATNQIEVHPYLQNRTLIAFLREQGI 173
Query: 686 AVMAY 700
V +Y
Sbjct: 174 HVTSY 178
>UniRef50_UPI00015B4B22 Cluster: PREDICTED: similar to GA15457-PA;
n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
GA15457-PA - Nasonia vitripennis
Length = 388
Score = 128 bits (310), Expect = 1e-28
Identities = 83/237 (35%), Positives = 129/237 (54%), Gaps = 12/237 (5%)
Frame = +2
Query: 38 VCLLXITFTRLLHAAMAVQAPCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAI 217
VCL+ + +L A AV+ ++L +G +P V LGT T K + + A+ A+
Sbjct: 8 VCLVVLAV--VLPGAQAVEK--LKLSSGHEIPAVGLGTS--TIKLDE----MDNAISSAL 57
Query: 218 EAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQES 397
E GYRHIDTA Y +E +G+ + + G RE++F+T+KL + + V L+ S
Sbjct: 58 ENGYRHIDTAFSYDNEAAIGKILKKWFDKG-GKREDIFITSKLPSQGNRPQSVETYLKRS 116
Query: 398 LKKLGLDYIDLYLIHFPIATKP------------DDSPDNIDYLETWQGMQDARQLGLAR 541
LK LGLDY+D+YLIH P A K +D D++D+ W+ M+ + G A+
Sbjct: 117 LKDLGLDYVDMYLIHTPFAVKEGENLSSKQDKDGNDLFDDVDHKALWKAMERQVKEGRAK 176
Query: 542 SIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
SIG+SNFN +Q+ + +N+ I+P Q+E + Q+ L C I + AY+P G
Sbjct: 177 SIGLSNFNQSQVLNIYNNAEIKPSNLQVETHAYLQQKQLRKFCKEHNIVMTAYAPLG 233
>UniRef50_Q1RFP0 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=21; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase
A - Escherichia coli (strain UTI89 / UPEC)
Length = 294
Score = 128 bits (310), Expect = 1e-28
Identities = 68/174 (39%), Positives = 100/174 (57%), Gaps = 1/174 (0%)
Frame = +2
Query: 194 RQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLW-NDKHARD 370
+Q+V AI GYR IDTAAVY +E+ VG+ + EAI+ GL TREELF+T+KLW D +D
Sbjct: 34 KQSVLNAIRTGYRLIDTAAVYGNEDAVGEAVREAISEGLCTREELFITSKLWVQDMLNQD 93
Query: 371 QVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIG 550
++ SLKK GL+Y DLYL+H + DY W+ ++DA + G ++IG
Sbjct: 94 IAAAGIEASLKKSGLEYFDLYLLHQAMR----------DYFSAWRALEDAYEEGKLKAIG 143
Query: 551 VSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
VSNF + ++P++NQ+E++P Q A + A++P G
Sbjct: 144 VSNFYPHVLANFCETVRVKPMVNQVELHPYFAQPEALATMKYYNVQPEAWAPLG 197
>UniRef50_A2QVE5 Cluster: Similarity: shows similarity to several
dehydrogenases of different specificities; n=4;
Pezizomycotina|Rep: Similarity: shows similarity to
several dehydrogenases of different specificities -
Aspergillus niger
Length = 381
Score = 128 bits (310), Expect = 1e-28
Identities = 78/222 (35%), Positives = 121/222 (54%), Gaps = 19/222 (8%)
Frame = +2
Query: 104 IQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 283
+ L++G +P + GT + V AVY A++AGYRH+D A +YQ++ +V +G
Sbjct: 7 VTLNSGAQIPQLGFGTWQSAP------GQVGDAVYEALKAGYRHLDLATIYQNQREVAEG 60
Query: 284 IAEAIAN--GLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA- 454
I A + GL RE++F+T+KLWN +H V AL E L +L LDY+DLYL+H+P++
Sbjct: 61 IKRAYKDVPGL-KREDIFITSKLWNSQHDPAVVEKALDECLAELELDYLDLYLVHWPVSF 119
Query: 455 -TKPDDSP---------------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRL 586
T + P D+I ++TW+ M + AR++GVSN + +
Sbjct: 120 TTGSELFPLVKDSSVEGGDVVINDDISIVDTWKAMTQLPK-SKARTVGVSNHMIPHLEAI 178
Query: 587 VSNSYIRPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
++ + + P +NQIE +P L +C GI V AYS FG
Sbjct: 179 INATGVVPAVNQIERHPVLQSNELIEYCQKKGIHVTAYSAFG 220
>UniRef50_Q7NB44 Cluster: ARA1; n=3; Firmicutes|Rep: ARA1 -
Mycoplasma gallisepticum
Length = 289
Score = 128 bits (309), Expect = 1e-28
Identities = 70/186 (37%), Positives = 107/186 (57%)
Frame = +2
Query: 152 GRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELF 331
G GT K D V +AV A+E GYRH+D A +Y+++ V QGI +G V R+E+F
Sbjct: 26 GFGTYKLEDGKQTV-EAVKTALEVGYRHLDCAEIYENQLSVSQGIK---LSG-VNRKEIF 80
Query: 332 VTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGM 511
+T+K+WND + A + LK L L+Y+DL LIH+PI D+ ++ +TW+ M
Sbjct: 81 ITSKIWNDDKGYESTKKAFHKILKDLDLEYLDLLLIHWPIGKGFKDNWQEVN-AQTWKAM 139
Query: 512 QDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEPLXAHCXSLGIAV 691
++ G ++IG+SNF I L ++ I P++NQ+E +P Q + +C I V
Sbjct: 140 EEFYLEGKIKAIGLSNFLVHHIEALKKSAKILPMVNQLEFHPGYLQPEIVEYCQKNNIVV 199
Query: 692 MAYSPF 709
A+SPF
Sbjct: 200 QAWSPF 205
>UniRef50_Q24C22 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=4; Oligohymenophorea|Rep: Oxidoreductase,
aldo/keto reductase family protein - Tetrahymena
thermophila SB210
Length = 297
Score = 128 bits (309), Expect = 1e-28
Identities = 72/208 (34%), Positives = 115/208 (55%), Gaps = 2/208 (0%)
Frame = +2
Query: 89 VQAPCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEE 268
V+ P + G +P + GT + +D I V +A ++ GY HIDTA+VY++E+
Sbjct: 11 VKVPILNFREGGSIPQIGYGTYE--LRQNDCIIGVTEA----LKIGYTHIDTASVYRNEQ 64
Query: 269 QVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFP 448
+ + I A G + RE+LF+T+K+ + +Q A+Q+ L +L + Y+D LIH+P
Sbjct: 65 DIAKVIHNP-AYG-IKREDLFITSKISPGEQGYEQAKKAVQDMLTRLNIKYLDCVLIHWP 122
Query: 449 IATK-PDDSPDNIDY-LETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQ 622
+K P + P N LETW+ + + R+ G+ + IGVSNFN + L+ S +P +NQ
Sbjct: 123 GVSKLPPNDPKNAQIRLETWKALIELRKAGVIKHIGVSNFNINHLQHLIEKSEFKPEMNQ 182
Query: 623 IEVNPTNTQEPLXAHCXSLGIAVMAYSP 706
E++P + C GI V AYSP
Sbjct: 183 FEIHPLCFNKKTIEFCQKNGILVEAYSP 210
>UniRef50_Q2UGR1 Cluster: Aldo/keto reductase family proteins; n=2;
Ascomycota|Rep: Aldo/keto reductase family proteins -
Aspergillus oryzae
Length = 323
Score = 128 bits (309), Expect = 1e-28
Identities = 80/215 (37%), Positives = 118/215 (54%), Gaps = 13/215 (6%)
Frame = +2
Query: 107 QLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGI 286
+L++G +P + LGT +K + V AV A+ AGYRHID AA YQ+E +VG G
Sbjct: 8 KLNSGYNIPAIGLGTW--LSKPHE----VENAVEAALRAGYRHIDAAACYQNENEVGNGW 61
Query: 287 AEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK-- 460
++ G V R+++F+T+KLWN H + V A+ ++LK L DY+DLYLIH+P+A +
Sbjct: 62 KKS---G-VPRDQIFITSKLWNTHHHPEHVEEAVNKTLKDLQTDYLDLYLIHWPVAFEHT 117
Query: 461 -----PDDSPD------NIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR 607
P D N+ +TW ++ + RSIG+SNF +I L+ + I
Sbjct: 118 NETLTPIDPVTKRFRLANVPIADTWAALEKLVEAKKIRSIGISNFTQDKIDDLLKTAKIP 177
Query: 608 PVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
P +NQIE +P Q L + I +AYSP G
Sbjct: 178 PAVNQIEAHPYLQQPGLHKYLKEKNILSVAYSPLG 212
>UniRef50_Q0SFM4 Cluster: Probable 2,5-didehydrogluconate reductase;
n=1; Rhodococcus sp. RHA1|Rep: Probable
2,5-didehydrogluconate reductase - Rhodococcus sp.
(strain RHA1)
Length = 265
Score = 127 bits (307), Expect = 2e-28
Identities = 71/172 (41%), Positives = 103/172 (59%)
Frame = +2
Query: 197 QAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQV 376
+AV IEAGYR IDTA +Y +E+ VG +AE G V REELFVTTKL H +
Sbjct: 21 RAVLSGIEAGYRLIDTATIYDNEDAVGVALAEC---G-VPREELFVTTKLRGSDHVSGDI 76
Query: 377 VPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVS 556
A++ SLK LGLD +DL+LIH+P+ P + Y+ ++ M R GL R +GVS
Sbjct: 77 RGAVERSLKNLGLDRLDLFLIHWPL-------PRHNRYVAAFEAMLACRDAGLVRHVGVS 129
Query: 557 NFNATQITRLVSNSYIRPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
NF T + R+V+ + P +NQI+++P+ + P+ LG++ ++SP G
Sbjct: 130 NFLETHLRRVVAETGESPAVNQIQMDPSLARLPVRRADDELGVSTQSWSPLG 181
>UniRef50_A6NPD6 Cluster: Putative uncharacterized protein; n=3;
Bacteria|Rep: Putative uncharacterized protein -
Bacteroides capillosus ATCC 29799
Length = 287
Score = 127 bits (307), Expect = 2e-28
Identities = 75/203 (36%), Positives = 114/203 (56%), Gaps = 2/203 (0%)
Frame = +2
Query: 110 LHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 289
L G +P V G GT K D V AI GYRH DTA+ Y E +GQ +A
Sbjct: 10 LSNGLSIPAV----GFGTYKTGDGDSAVLSN---AIAQGYRHFDTASFYGTETALGQAVA 62
Query: 290 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDD 469
E+ + RE+ F+T+KLW + D + A +L++LG DY+DLYLIH+P +PD
Sbjct: 63 ESD----IPREDFFLTSKLWKTEMGYDAALRAFDATLERLGTDYLDLYLIHWP---RPDL 115
Query: 470 SPDNIDYL--ETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTN 643
++ L ETW+ ++ + GL R+IGVSNF + +++++ + P+++Q+E +P
Sbjct: 116 ELEDWAKLDRETWRALERLYESGLVRAIGVSNFLPHHLEPILASANVAPMVDQLEFHPGY 175
Query: 644 TQEPLXAHCXSLGIAVMAYSPFG 712
TQ+ A C + I V A+SP G
Sbjct: 176 TQDEAVAFCQNHSILVEAWSPLG 198
>UniRef50_P47137 Cluster: Probable oxidoreductase YJR096W; n=8;
Saccharomycetales|Rep: Probable oxidoreductase YJR096W -
Saccharomyces cerevisiae (Baker's yeast)
Length = 282
Score = 127 bits (307), Expect = 2e-28
Identities = 78/205 (38%), Positives = 118/205 (57%), Gaps = 5/205 (2%)
Frame = +2
Query: 107 QLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGI 286
+L G +P +ALGT + I VY ++ GYRH DTA +Y +E++VG GI
Sbjct: 7 KLSNGFKIPSIALGTYDIPRSQTAEI------VYEGVKCGYRHFDTAVLYGNEKEVGDGI 60
Query: 287 AEAIAN--GLVTREELFVTTKLWNDKHARDQVVPALQESLKKL-GLDYIDLYLIHFPIAT 457
+ + G REE+F TTKLWN ++ + A+++ L ++ GL YIDL LIH P+
Sbjct: 61 IKWLNEDPGNHKREEIFYTTKLWNSQNGYKRAKAAIRQCLNEVSGLQYIDLLLIHSPL-- 118
Query: 458 KPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI--RPVINQIEV 631
+ S LETW+ MQ+A GL +SIGVSN+ I L++ + +PV+NQIE+
Sbjct: 119 --EGSKLR---LETWRAMQEAVDEGLVKSIGVSNYGKKHIDELLNWPELKHKPVVNQIEI 173
Query: 632 NPTNTQEPLXAHCXSLGIAVMAYSP 706
+P ++ L +C S G+ V A++P
Sbjct: 174 SPWIMRQELADYCKSKGLVVEAFAP 198
>UniRef50_Q22352 Cluster: Putative uncharacterized protein T08H10.1;
n=2; Caenorhabditis|Rep: Putative uncharacterized
protein T08H10.1 - Caenorhabditis elegans
Length = 333
Score = 127 bits (306), Expect = 3e-28
Identities = 75/215 (34%), Positives = 118/215 (54%), Gaps = 12/215 (5%)
Frame = +2
Query: 104 IQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 283
I L+ G LP LGT + K + +A A++AGYR IDTA +YQ+E +G+
Sbjct: 6 IPLNTGAQLPLFGLGTWQ--VKDEAELTVALRA---ALDAGYRLIDTAHLYQNEHIIGKV 60
Query: 284 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 463
+ E I++G + RE++FVT+KL HA + V ++ LK L L+YIDLYLIH P K
Sbjct: 61 LHEYISSGKLKREDIFVTSKLPFTAHAPEDVPKCVESQLKALQLEYIDLYLIHCPFPFKH 120
Query: 464 DD------------SPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR 607
+ + I +++TW+ ++ + G +++GVSNF+ Q+ L + ++
Sbjct: 121 QEGSFAPLMENGELAVTEIAHIDTWRALEKLYKEGKLKALGVSNFSCNQLQALYDAAEVK 180
Query: 608 PVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
P Q+E + Q+ L A C LG+ V AY+P G
Sbjct: 181 PANQQVECHIYWPQQELRALCKKLGVTVTAYAPLG 215
>UniRef50_P15339 Cluster: 2,5-diketo-D-gluconic acid reductase B;
n=6; Actinomycetales|Rep: 2,5-diketo-D-gluconic acid
reductase B - Corynebacterium sp. (strain SHS752001)
Length = 277
Score = 126 bits (305), Expect = 4e-28
Identities = 76/203 (37%), Positives = 114/203 (56%)
Frame = +2
Query: 98 PCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 277
P I L+ G P LGT + + + A+ AI++GYR +DTA Y++E +VG
Sbjct: 5 PTISLNDGRPFAEPGLGTYN--LRGDEGVA----AMVAAIDSGYRLLDTAVNYENESEVG 58
Query: 278 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 457
+ A+ V R+EL V +K+ +H R + V +++ SL +LGLD IDL LIH+P
Sbjct: 59 R----AVRASSVDRDELIVASKIPGRQHGRAEAVDSIRGSLDRLGLDVIDLQLIHWP--- 111
Query: 458 KPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNP 637
+P +L+TW+GM DAR+ GL RSIGVSNF + L+ + + P +NQ+E++P
Sbjct: 112 ----NPSVGRWLDTWRGMIDAREAGLVRSIGVSNFTEPMLKTLIDETGVTPAVNQVELHP 167
Query: 638 TNTQEPLXAHCXSLGIAVMAYSP 706
Q L A GI ++SP
Sbjct: 168 YFPQAALRAFHDEHGIRTESWSP 190
>UniRef50_A7PNI3 Cluster: Chromosome chr1 scaffold_22, whole genome
shotgun sequence; n=2; Vitis vinifera|Rep: Chromosome
chr1 scaffold_22, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 360
Score = 126 bits (304), Expect = 6e-28
Identities = 72/188 (38%), Positives = 115/188 (61%), Gaps = 12/188 (6%)
Frame = +2
Query: 197 QAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQV 376
+AV A+ GYR ID A +Y +E +VG+ +AEA NG + RE++F+T+KL+ ++ +++
Sbjct: 37 EAVKRALSEGYRQIDCAHLYGNEVEVGEALAEAF-NGSLKREDVFLTSKLYCTMNSLNKI 95
Query: 377 VPALQESLKKLGLDYIDLYLIHFPI------ATKPDDSP--DNIDYL----ETWQGMQDA 520
+++ SLK LG+ Y+DLYL+H+P AT P + D+ +L + W+ M+
Sbjct: 96 ENSVRVSLKNLGVTYLDLYLMHWPDITAFGDATDPPSNSGNDHRQFLNRLKKAWKAMEGL 155
Query: 521 RQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEPLXAHCXSLGIAVMAY 700
+LGL R+IGVSNF QI L+ + I P +NQ++++P Q+ L C S GI V A+
Sbjct: 156 IELGLVRAIGVSNFGVQQIKELLKFAKIVPAVNQVKLHPFWRQDELVKFCQSKGIHVSAH 215
Query: 701 SPFGFVVS 724
+P G S
Sbjct: 216 TPLGVPAS 223
>UniRef50_Q7QVQ9 Cluster: GLP_302_44328_45269; n=1; Giardia lamblia
ATCC 50803|Rep: GLP_302_44328_45269 - Giardia lamblia
ATCC 50803
Length = 313
Score = 126 bits (304), Expect = 6e-28
Identities = 65/189 (34%), Positives = 108/189 (57%), Gaps = 15/189 (7%)
Frame = +2
Query: 191 VRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAI--ANGLVTREELFVTTKLWNDKHA 364
V+ AV A+ GYRHID A VYQ+EE +G+ + A+ + RE++++T+KLWN H
Sbjct: 19 VQTAVETALMTGYRHIDCAYVYQNEEAIGRAFGKIFKDASSGIKREDVWITSKLWNYNHR 78
Query: 365 RDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPD-------------NIDYLETWQ 505
+ V ++++ L +DY+DL+L+H+P+A +D D + +TW+
Sbjct: 79 PELVREQCKKTMSDLQVDYLDLFLVHWPLAFVRNDVGDLFPKDAEGRAMLEKVPLADTWR 138
Query: 506 GMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEPLXAHCXSLGI 685
M+ + GL + IGVSN+ + L++ + I+P++NQIE++P + + C GI
Sbjct: 139 AMEQLVEEGLVKHIGVSNYTVPLLADLLNYAKIKPLVNQIEIHPWHPNDATVKFCLDNGI 198
Query: 686 AVMAYSPFG 712
V AYSP G
Sbjct: 199 GVTAYSPMG 207
>UniRef50_Q6F7K7 Cluster: 2,5-diketo-D-gluconate reductase; n=20;
Bacteria|Rep: 2,5-diketo-D-gluconate reductase -
Acinetobacter sp. (strain ADP1)
Length = 297
Score = 126 bits (303), Expect = 7e-28
Identities = 78/205 (38%), Positives = 116/205 (56%)
Frame = +2
Query: 98 PCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 277
P + LH G +P ALG G T K + + +A + GYR +D+A Y++E VG
Sbjct: 23 PDLILHDGHSIP--ALGFGTYTLKGQQGVDTMLRA----LGHGYRMLDSAFNYENEGAVG 76
Query: 278 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 457
+ ++ GL+ R+E+F+T+KL HA D+ + ++ESL ++ DY+DLYLIH+P
Sbjct: 77 AAVRQS---GLL-RDEIFITSKLPGRHHAYDKAMETIEESLYRMQFDYLDLYLIHWP--- 129
Query: 458 KPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNP 637
+P Y+E WQ + DA++ G RSIGVSNF I L + + PVINQ+E++P
Sbjct: 130 ----NPQQGLYIEAWQALIDAQKKGYIRSIGVSNFLPKHIETLRRETGVIPVINQVELHP 185
Query: 638 TNTQEPLXAHCXSLGIAVMAYSPFG 712
Q A+ S I MA+SP G
Sbjct: 186 YFNQAEQRAYDESQQIITMAWSPLG 210
>UniRef50_A2UAH0 Cluster: Aldo/keto reductase; n=1; Bacillus
coagulans 36D1|Rep: Aldo/keto reductase - Bacillus
coagulans 36D1
Length = 273
Score = 126 bits (303), Expect = 7e-28
Identities = 69/199 (34%), Positives = 111/199 (55%)
Frame = +2
Query: 110 LHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 289
L G +P + LGT + + AV +A++ GYRHIDTA Y +EE VG+
Sbjct: 10 LENGVAIPKIGLGTWQ-----VPNGETTYHAVSFALKNGYRHIDTAYAYHNEESVGK--- 61
Query: 290 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDD 469
A+ + + R ++FVT+KL + + D+ + E++ GL+ +DLYLIH P
Sbjct: 62 -AVRDSGIDRRDIFVTSKLPAEIKSYDKALKTFDETMGNFGLEQLDLYLIHAPWPWSEKG 120
Query: 470 SPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQ 649
+ + +E W+ M++ + G R+IGVSNF+ + + ++ N+ I+P++NQI +TQ
Sbjct: 121 ADYTKENIEVWKAMEEIYESGRCRAIGVSNFSVSDLKAVMENAKIKPMVNQIRYFIGHTQ 180
Query: 650 EPLXAHCXSLGIAVMAYSP 706
E + A C GI V AYSP
Sbjct: 181 EDVTAFCQDNGILVEAYSP 199
>UniRef50_A5PDA8 Cluster: Putative oxidoreductase protein; n=1;
Erythrobacter sp. SD-21|Rep: Putative oxidoreductase
protein - Erythrobacter sp. SD-21
Length = 272
Score = 125 bits (302), Expect = 1e-27
Identities = 67/205 (32%), Positives = 115/205 (56%)
Frame = +2
Query: 98 PCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 277
P + L+ G +P + GT + + + QAV AI+ GY IDTAA+Y +E+ VG
Sbjct: 5 PTLNLNDGRQIPQLGFGTWQMEEEDAP------QAVSTAIDVGYWLIDTAAIYGNEKGVG 58
Query: 278 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 457
+G+ E ++F+ TK+WND D+ + A ++ L++LG +++D+ LIH+P
Sbjct: 59 KGVGEW--------SDIFLQTKIWNDSQGYDRTLRAAEKCLERLGREHVDMLLIHWPC-- 108
Query: 458 KPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNP 637
P+ +++TW+ + + R G A+SIGVSNF + R++ + + P +NQIE++P
Sbjct: 109 -----PEKDQFVDTWKALIELRDAGKAKSIGVSNFREEDLKRIIDETGVTPALNQIELHP 163
Query: 638 TNTQEPLXAHCXSLGIAVMAYSPFG 712
+ Q + LGI ++SP G
Sbjct: 164 SFQQRDMRKVHEDLGIVTQSWSPLG 188
>UniRef50_Q8SSK6 Cluster: ALDOSE REDUCTASE; n=1; Encephalitozoon
cuniculi|Rep: ALDOSE REDUCTASE - Encephalitozoon
cuniculi
Length = 301
Score = 125 bits (302), Expect = 1e-27
Identities = 74/213 (34%), Positives = 114/213 (53%), Gaps = 11/213 (5%)
Frame = +2
Query: 107 QLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGI 286
+L+ G +P V LGT + + A+ A+ GYRHIDTA +Y +E+ +G +
Sbjct: 7 KLNNGKEIPTVGLGTW-----GMEDEAVLEGAIRNALSLGYRHIDTAFIYGNEKMIGNIL 61
Query: 287 AEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA--TK 460
+ G+V R++LF+T+KLWN H + L+ SL L +DY+DLYLIH+P+
Sbjct: 62 KKLFDEGVVQRKDLFITSKLWNTFHGCPE--DGLRRSLNDLQMDYVDLYLIHWPVTFDPA 119
Query: 461 PDDSPDN---------IDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPV 613
PD + ++ D + W+ M+ LGLA+SIG+SNF +++ I P
Sbjct: 120 PDGTVESCGKKYNVGKFDAVGVWKKMEALVDLGLAKSIGISNFGKANTEKILGTCRICPA 179
Query: 614 INQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
QIE++P Q+ L S GI V++YS G
Sbjct: 180 AIQIELHPYLNQKELVEFMKSKGIQVISYSSLG 212
>UniRef50_O13848 Cluster: NADH/NADPH dependent indole-3-acetaldehyde
reductase AKR3C2; n=1; Schizosaccharomyces pombe|Rep:
NADH/NADPH dependent indole-3-acetaldehyde reductase
AKR3C2 - Schizosaccharomyces pombe (Fission yeast)
Length = 284
Score = 125 bits (302), Expect = 1e-27
Identities = 77/201 (38%), Positives = 106/201 (52%), Gaps = 2/201 (0%)
Frame = +2
Query: 125 PLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIAN 304
P+P +GT + + + +V A+ AG+ HID A VY +EE+VG + EA
Sbjct: 11 PVPAYGVGTALFKKEKGEINRTIVDSVKNALAAGFIHIDCAEVYGNEEEVGVALKEAN-- 68
Query: 305 GLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNI 484
V R +LF+T+K+ H D + AL ESL+KLG DY+DLYL+H PI P +
Sbjct: 69 --VPRSKLFITSKVM---HNVDNIPEALNESLRKLGTDYLDLYLLHSPIPFYEKKIPIS- 122
Query: 485 DYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPT--NTQEPL 658
E W+ M+ A GL S+GVSNF + L+ S I P +NQIE +P +PL
Sbjct: 123 ---EGWKAMETALGTGLVHSVGVSNFRIPDLEELLKTSTITPRVNQIEFHPQVYKAAKPL 179
Query: 659 XAHCXSLGIAVMAYSPFGFVV 721
C S GI V Y P +V
Sbjct: 180 VEFCQSKGIIVEGYGPLSPLV 200
>UniRef50_Q927E1 Cluster: Lin2848 protein; n=13; Listeria|Rep:
Lin2848 protein - Listeria innocua
Length = 280
Score = 124 bits (300), Expect = 2e-27
Identities = 71/187 (37%), Positives = 110/187 (58%)
Frame = +2
Query: 152 GRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELF 331
G G K +D +R A+ A++ GYR DTA+ Y +E+++G A ++GL R+E F
Sbjct: 21 GFGVYKLTDE-QRMRTALETAVDVGYRLFDTASFYHNEKELGDFFA---SSGL-KRDEFF 75
Query: 332 VTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGM 511
VTTK+WN + D+ + A ++S KKL LD +DLYL+H+P K D + ETW+ +
Sbjct: 76 VTTKMWNTEQGYDETLRAFEKSQKKLQLDQVDLYLVHWP---KQD------TFFETWRAV 126
Query: 512 QDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEPLXAHCXSLGIAV 691
+ GL R+IGVSNF A + RL +++ + PV++Q+E +P + L + L I
Sbjct: 127 EKLYDEGLVRAIGVSNFEAHHLDRLRTSANVLPVVDQLETHPHFPNQLLHRYLEELHIVH 186
Query: 692 MAYSPFG 712
A+SP G
Sbjct: 187 QAWSPLG 193
>UniRef50_Q6C2L0 Cluster: Yarrowia lipolytica chromosome F of strain
CLIB122 of Yarrowia lipolytica; n=3; Yarrowia
lipolytica|Rep: Yarrowia lipolytica chromosome F of
strain CLIB122 of Yarrowia lipolytica - Yarrowia
lipolytica (Candida lipolytica)
Length = 324
Score = 124 bits (300), Expect = 2e-27
Identities = 83/219 (37%), Positives = 116/219 (52%), Gaps = 17/219 (7%)
Frame = +2
Query: 107 QLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGI 286
+L+ G +P + LGT SD V + VY AI+ GYRHIDTA +Y E VG+GI
Sbjct: 8 KLNDGHSIPALGLGTA------SDG--NVEEVVYAAIKNGYRHIDTAFIYGSEVDVGKGI 59
Query: 287 AEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPD 466
AI LV RE LFVTTK+W + R V +L SLK L LDY+DL L+H+P++ D
Sbjct: 60 KRAIDEELVKRENLFVTTKVWPTFYNR--VSESLDISLKDLSLDYVDLLLVHWPVSLLAD 117
Query: 467 -DSPDNI----------------DYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSN 595
D P I D++ T++ +++ + G +SIGVSN + + RL+
Sbjct: 118 SDDPRAIYLVNTDGSVRYSDSLDDWITTYKQIEEEKLSGRTKSIGVSNVSEVYLKRLLDQ 177
Query: 596 SYIRPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
P +NQ E++P Q+ GI V A+SP G
Sbjct: 178 VKTVPAVNQFEIHPYLPQKKEIEFNEKHGILVTAFSPLG 216
>UniRef50_Q88TV9 Cluster: Oxidoreductase; n=4; Lactobacillus|Rep:
Oxidoreductase - Lactobacillus plantarum
Length = 288
Score = 124 bits (298), Expect = 3e-27
Identities = 77/207 (37%), Positives = 108/207 (52%)
Frame = +2
Query: 92 QAPCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQ 271
+ P I L+ G +P + G GT + D QAV A+ GYRHIDTA Y +E++
Sbjct: 3 KTPTITLNDGRAIPAI----GFGTFQIPDD-GSTYQAVKEALVIGYRHIDTAVAYFNEDE 57
Query: 272 VGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPI 451
VGQ AI + + R++++VT+KLW + D A+ SL KL LDYIDLYLIH P
Sbjct: 58 VGQ----AIKDSGIPRDQIWVTSKLWLQDYGFDAASRAIDRSLTKLRLDYIDLYLIHQPY 113
Query: 452 ATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEV 631
P WQ M+ A++ G +SIGVSN T + V P +NQ+E
Sbjct: 114 GDVPG----------AWQAMEAAQKAGKLKSIGVSNMTPTLWQKFVPQFETIPAVNQVEF 163
Query: 632 NPTNTQEPLXAHCXSLGIAVMAYSPFG 712
NP Q+PL + + + A++P G
Sbjct: 164 NPYFQQQPLRQLLAAQDVKLEAWAPLG 190
>UniRef50_Q7WSY4 Cluster: Putative aldo-keto reductase; n=1;
Propionibacterium freudenreichii subsp. shermanii|Rep:
Putative aldo-keto reductase - Propionibacterium
freudenreichii subsp. shermanii
Length = 280
Score = 124 bits (298), Expect = 3e-27
Identities = 74/205 (36%), Positives = 117/205 (57%)
Frame = +2
Query: 98 PCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 277
P ++L G +P + +GT K + R AV AIE GYR +DTA Y +EE VG
Sbjct: 9 PTVELSGGTRMPMLGMGTW--PLKGEEC----RAAVASAIEQGYRLVDTAEAYGNEEAVG 62
Query: 278 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 457
+ + EA + R E+FVTTK H+R V AL+ SL++LGLDY+DL+L+H+P+
Sbjct: 63 KAVREAGPD----RAEIFVTTKFSKQWHSRKGVHEALEHSLERLGLDYVDLFLMHWPM-- 116
Query: 458 KPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNP 637
P Y++ ++GM + ++ GLA++IGVSNF + L++ + P +NQI+++P
Sbjct: 117 -----PGEGSYVDAYRGMVELKEQGLAKAIGVSNFKVHHLDDLITEG-MTPEVNQIQLDP 170
Query: 638 TNTQEPLXAHCXSLGIAVMAYSPFG 712
+ + + + I A+SP G
Sbjct: 171 SRPRLEVRDFLDNHDIVTEAWSPLG 195
>UniRef50_A3VHZ9 Cluster: Oxidoreductase; n=1; Rhodobacterales
bacterium HTCC2654|Rep: Oxidoreductase - Rhodobacterales
bacterium HTCC2654
Length = 278
Score = 123 bits (297), Expect = 4e-27
Identities = 79/206 (38%), Positives = 117/206 (56%)
Frame = +2
Query: 95 APCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQV 274
AP + L G +P + LGT T + +AV AIE GYR IDTA Y++E V
Sbjct: 7 APTVTLANGVEMPQLGLGTWPMTDDEA------AKAVATAIETGYRLIDTAENYKNETGV 60
Query: 275 GQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA 454
GQGI +A G V R+E+F+TTK+ H+ D A + SL++LGLDYIDL+LIH+P
Sbjct: 61 GQGIRDA---G-VARDEVFLTTKMNKQWHSVDGARRACEASLERLGLDYIDLFLIHWP-- 114
Query: 455 TKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVN 634
+PD Y+E ++G+ GL R+IG SNF + L + ++ P +NQI+++
Sbjct: 115 -----NPDQGTYVEAFEGLTRLLDAGLVRAIGTSNFLPHHLNDLFAAGFV-PHVNQIQLD 168
Query: 635 PTNTQEPLXAHCXSLGIAVMAYSPFG 712
P + + + A + GI ++SP G
Sbjct: 169 PYHLRPDITAIHAAKGIVTESWSPIG 194
>UniRef50_Q9ZUJ6 Cluster: T2K10.1 protein; n=16; core
eudicotyledons|Rep: T2K10.1 protein - Arabidopsis
thaliana (Mouse-ear cress)
Length = 176
Score = 123 bits (297), Expect = 4e-27
Identities = 64/139 (46%), Positives = 94/139 (67%), Gaps = 10/139 (7%)
Frame = +2
Query: 191 VRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLV-TREELFVTTKLW-NDKHA 364
+++ V AI+ GYRH DT+ YQ EE +G+ +AEA++ GLV +R E FVTTKLW D H
Sbjct: 39 LKETVIEAIKLGYRHFDTSPRYQTEEPIGEALAEAVSLGLVRSRSEFFVTTKLWCADAHG 98
Query: 365 RDQVVPALQESLKKLGLDYIDLYLIHFPIATKP--------DDSPDNIDYLETWQGMQDA 520
VVPA++ SLK L LDY+DLY+IH+P+++KP +D +D+ W M++
Sbjct: 99 -GLVVPAIKRSLKNLKLDYLDLYIIHWPVSSKPGKYKFPIDEDDFMPMDFEVVWSEMEEC 157
Query: 521 RQLGLARSIGVSNFNATQI 577
++LGLA+ IGVSNF+ ++
Sbjct: 158 QRLGLAKCIGVSNFSCKKL 176
>UniRef50_UPI00006CA3CB Cluster: oxidoreductase, aldo/keto reductase
family protein; n=3; Tetrahymena thermophila SB210|Rep:
oxidoreductase, aldo/keto reductase family protein -
Tetrahymena thermophila SB210
Length = 299
Score = 123 bits (296), Expect = 5e-27
Identities = 69/203 (33%), Positives = 110/203 (54%), Gaps = 2/203 (0%)
Frame = +2
Query: 104 IQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 283
I L G +P LG+ R S+ V + A++ GYRHIDTA +Y++E+ +G
Sbjct: 10 ITLSNGQKMPAFGLGSSR-----VQSVEEVTNLIRKALDVGYRHIDTAQMYENEQFIGAA 64
Query: 284 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 463
+ G RE++F+ TK + K + ++E L+KL +DY+DL LIH P+A
Sbjct: 65 LKTIFGEGKYKREDIFLVTKQASIKGV--SCLEIMKEQLQKLQVDYVDLLLIHVPLAAPS 122
Query: 464 DDSP--DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNP 637
DD ++ + W ++ LGLA+ +GVSNFN I L++ I+P++NQIE++
Sbjct: 123 DDYQQWNHKPVHQIWAEFEEIHSLGLAKGLGVSNFNCQMIIDLLAYCKIKPLVNQIELHV 182
Query: 638 TNTQEPLXAHCXSLGIAVMAYSP 706
N Q+ L + I +A+SP
Sbjct: 183 FNQQKNLVEFLKKVNIYPVAFSP 205
>UniRef50_Q5HR31 Cluster: Oxidoreductase, aldo/keto reductase
family; n=3; Staphylococcus|Rep: Oxidoreductase,
aldo/keto reductase family - Staphylococcus epidermidis
(strain ATCC 35984 / RP62A)
Length = 279
Score = 123 bits (296), Expect = 5e-27
Identities = 71/199 (35%), Positives = 111/199 (55%)
Frame = +2
Query: 110 LHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 289
L+ G P+P V LG K +D + + V A++AGYR DTA Y +E+ +G
Sbjct: 8 LNNGYPMPAVGLGV----YKIADE--QMEEVVRTALDAGYRAFDTAYFYGNEKALGS--- 58
Query: 290 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDD 469
A+ + V R+ELF+T+KLWND DQ + +SL LGLDY+DL+LIH+P
Sbjct: 59 -ALKHSNVERDELFITSKLWNDYQGYDQTIEYFNKSLDNLGLDYLDLFLIHWPCEN---- 113
Query: 470 SPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQ 649
D + Y+E+++ ++ + G ++IGV NF + +L+ + I P +NQIE++P Q
Sbjct: 114 --DQL-YIESYKALEHLYEEGKIKAIGVCNFKIHHLEKLMKETKITPQVNQIELHPYFNQ 170
Query: 650 EPLXAHCXSLGIAVMAYSP 706
+ + C I V A+ P
Sbjct: 171 QDVQDFCDEHDIKVTAWMP 189
>UniRef50_A2EYY6 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=9; Trichomonas vaginalis G3|Rep:
Oxidoreductase, aldo/keto reductase family protein -
Trichomonas vaginalis G3
Length = 308
Score = 123 bits (296), Expect = 5e-27
Identities = 75/203 (36%), Positives = 106/203 (52%), Gaps = 16/203 (7%)
Frame = +2
Query: 152 GRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELF 331
G GT K S V Y EAGY HID A Y++E+ VGQ + + +G + RE ++
Sbjct: 8 GLGTWKSPRSEDLVNAITYAIKEAGYVHIDCALCYENEDIVGQALQQCWDSG-IKRENIW 66
Query: 332 VTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA---------TKPDDS---- 472
+T+KLWN H + V A +++LK L LDY+DLYL+H+P A P D
Sbjct: 67 ITSKLWNTHHRLEIVEEACRKTLKDLRLDYLDLYLMHYPFAFQNTGIGGSLNPLDEKGNT 126
Query: 473 --PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRL-VSNSYIRPVINQIEVNPTN 643
D + ++TW+ M+ + GL + IGVSN+ Q+ RL S++ P NQ+E N
Sbjct: 127 IFDDGVSLIDTWKAMEKLVEKGLVKRIGVSNWTINQLERLKYSDAKTTPYTNQVEFNLYM 186
Query: 644 TQEPLXAHCXSLGIAVMAYSPFG 712
Q PL + GI V YS G
Sbjct: 187 QQGPLREYMHKEGIIVTGYSTLG 209
>UniRef50_Q8ET73 Cluster: 2,5-diketo-D-gluconate reductase; n=12;
Bacteria|Rep: 2,5-diketo-D-gluconate reductase -
Oceanobacillus iheyensis
Length = 280
Score = 122 bits (295), Expect = 7e-27
Identities = 81/208 (38%), Positives = 109/208 (52%)
Frame = +2
Query: 83 MAVQAPCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQD 262
M Q P + LH G +P V GT R +D + QA+ AI+ GYR IDTA Y++
Sbjct: 1 MVNQIPNVTLHDGLTIPKVGFGTYR--LNGNDGV----QAINNAIDHGYRLIDTAYNYEN 54
Query: 263 EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIH 442
E VG EA+ RE+L +T+KL H D+ V +QESL + LDY DLYLIH
Sbjct: 55 EGTVG----EAVRRSSTPREQLLITSKLPGRYHHYDKAVTTIQESLYRANLDYYDLYLIH 110
Query: 443 FPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQ 622
+P +P Y+E WQ + +A++ G RSIGV NF + RL + P INQ
Sbjct: 111 WP-------NPIQDIYVEAWQALIEAKRRGYIRSIGVCNFLPEHLERLKQETGELPTINQ 163
Query: 623 IEVNPTNTQEPLXAHCXSLGIAVMAYSP 706
IE++P QE IA ++SP
Sbjct: 164 IELHPFFNQEDQRKWHQEHQIATESWSP 191
>UniRef50_Q15NA5 Cluster: Aldo/keto reductase; n=2;
Gammaproteobacteria|Rep: Aldo/keto reductase -
Pseudoalteromonas atlantica (strain T6c / BAA-1087)
Length = 273
Score = 122 bits (295), Expect = 7e-27
Identities = 69/172 (40%), Positives = 103/172 (59%), Gaps = 1/172 (0%)
Frame = +2
Query: 200 AVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVV 379
AV A++ GYRHIDTA Y++E +VG +AI+ ++R ELFVTTK+W D + D+ +
Sbjct: 29 AVENALDVGYRHIDTAQAYENEAEVG----DAISASKISRGELFVTTKVWFDNLSADKFI 84
Query: 380 PALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSN 559
++Q SL +L DY+DL L+H+P PD+ +YL+ ++ ++ GL R IGVSN
Sbjct: 85 TSVQNSLTQLNTDYVDLLLVHWP---SPDNKVSMAEYLKE---LKACKERGLTRHIGVSN 138
Query: 560 FNATQITRLVSNSYIRPVI-NQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
F +Q+ +S ++ NQIEV+P + L A+C I V AY P G
Sbjct: 139 FTQSQLDEALSILGKDHILTNQIEVHPNFQNKELVAYCQRNNIQVTAYMPLG 190
>UniRef50_A0JX62 Cluster: 2,5-didehydrogluconate reductase; n=9;
Bacteria|Rep: 2,5-didehydrogluconate reductase -
Arthrobacter sp. (strain FB24)
Length = 291
Score = 122 bits (295), Expect = 7e-27
Identities = 71/183 (38%), Positives = 102/183 (55%), Gaps = 13/183 (7%)
Frame = +2
Query: 203 VYWAIEAGYRHIDTAAVYQDEEQVGQGIAE--AIANG-----------LVTREELFVTTK 343
V A+EAGYRH DTAA+Y +E VG+ I A G ++RE+LFVTTK
Sbjct: 34 VTMALEAGYRHFDTAAMYGNETGVGKAIGALAGFAGGGPAGGSGEAAPSLSREDLFVTTK 93
Query: 344 LWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDAR 523
+WND H D + A S+ LG++Y+DLYLIH+P A + + E+++ M+
Sbjct: 94 VWNDDHGYDATMRAFDTSMSNLGMEYVDLYLIHWPCARRG-------LFTESYRAMETLY 146
Query: 524 QLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYS 703
+ G R+IGVSNF + L+ + + P +NQIE++P Q+ L LGI A+S
Sbjct: 147 REGRIRAIGVSNFQPAHLEHLLETAEVVPAVNQIELHPWLQQDELRQLHDRLGIRTEAWS 206
Query: 704 PFG 712
P G
Sbjct: 207 PLG 209
>UniRef50_Q4PDR0 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 339
Score = 122 bits (295), Expect = 7e-27
Identities = 84/227 (37%), Positives = 116/227 (51%), Gaps = 17/227 (7%)
Frame = +2
Query: 83 MAVQAPCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQD 262
MA P L+ G LP V +G +G V A+ AI+ GYRH+DTA Y++
Sbjct: 1 MAANIPSFTLNTGAKLPSVGMGCWQGQPGPGRDNELV-DALVRAIKVGYRHLDTATGYRN 59
Query: 263 EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIH 442
E +VGQ + ++ G V R E+FVTTKL D VV L+ SL +LG+DYIDL+L+H
Sbjct: 60 EAEVGQAVRQS---G-VARSEIFVTTKL-RPGGVHD-VVQELENSLNELGIDYIDLWLLH 113
Query: 443 FPIATKPDDSP---------DNIDYL-----ETWQGMQDA---RQLGLARSIGVSNFNAT 571
+P DD ++ +L ETW M+D G ++IGVSNF+
Sbjct: 114 WPQGFTKDDGGFGTGESFGLEHQKHLGPTFNETWAKMEDVFLNSHKGKVKAIGVSNFSIK 173
Query: 572 QITRLVSNSYIRPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+ L S + P +NQIE +P + L +C I V AYSP G
Sbjct: 174 NLEILAKTSKVTPAVNQIEAHPYLPEHELVKYCKHKSIHVTAYSPLG 220
>UniRef50_UPI0000DB6EE9 Cluster: PREDICTED: similar to C35D10.6;
n=2; Endopterygota|Rep: PREDICTED: similar to C35D10.6 -
Apis mellifera
Length = 292
Score = 122 bits (294), Expect = 9e-27
Identities = 72/205 (35%), Positives = 110/205 (53%), Gaps = 4/205 (1%)
Frame = +2
Query: 110 LHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 289
L +G +P + GT + + V Q V ++ G+R IDTA Y++EE +G +
Sbjct: 10 LSSGYDMPLIGFGTYKIQGRE-----LVYQVVDESLNVGFRSIDTAVGYRNEEDIGYALK 64
Query: 290 EAIANGLVTREELFVTTKLWNDKHARDQ-VVPALQESLKKLGLDYIDLYLIHFPIATK-P 463
+ + R ++F+TTKL + + + +Q+SLK YIDLYLIH+P AT+ P
Sbjct: 65 NLLPKYNLQRSDIFITTKLPPSVNGDPKGIEQCVQKSLKAFNTTYIDLYLIHWPGATRIP 124
Query: 464 DDSPDNIDY-LETWQGMQDARQLGLARSIGVSNFNATQITRLVSN-SYIRPVINQIEVNP 637
+ S +N +TW + D ++ G RSIGVSNF + L+ N I P +NQ+E++P
Sbjct: 125 ETSTNNPSLRAKTWNKLVDLKKQGFIRSIGVSNFTIKHLQELLQNCKDILPAVNQVELHP 184
Query: 638 TNTQEPLXAHCXSLGIAVMAYSPFG 712
QE L +C GI + AYS G
Sbjct: 185 HYRQEELIKYCNEKGIHIQAYSSLG 209
>UniRef50_Q929C8 Cluster: Lin2349 protein; n=12; Listeria|Rep:
Lin2349 protein - Listeria innocua
Length = 294
Score = 122 bits (293), Expect = 1e-26
Identities = 69/169 (40%), Positives = 99/169 (58%)
Frame = +2
Query: 200 AVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVV 379
AV AIE GYR DTAAVY +E VGQ AI + V REELF+++K+WN D+ +
Sbjct: 36 AVEKAIEVGYRLFDTAAVYNNEAIVGQ----AILDSAVPREELFISSKVWNGDLGYDETL 91
Query: 380 PALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSN 559
A + +L+ L LDY+DLYLIH+P+A K Y ++W+ M+ L +SIGV+N
Sbjct: 92 FAFERTLRNLKLDYLDLYLIHWPVAGK---------YRDSWRAMERLHDEKLIKSIGVAN 142
Query: 560 FNATQITRLVSNSYIRPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSP 706
F ++ L+ + +PV+NQ+E +P Q L + IA A+SP
Sbjct: 143 FKQHHLSDLLVAANEKPVLNQVETHPLLPQNDLRKYLAEQNIAHAAWSP 191
>UniRef50_A5VK30 Cluster: 2,5-didehydrogluconate reductase; n=2;
Lactobacillus reuteri|Rep: 2,5-didehydrogluconate
reductase - Lactobacillus reuteri F275
Length = 300
Score = 122 bits (293), Expect = 1e-26
Identities = 75/206 (36%), Positives = 114/206 (55%), Gaps = 1/206 (0%)
Frame = +2
Query: 98 PCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 277
P I+L+ G +P + LG + S+ +Q V AI Y IDTA Y +E VG
Sbjct: 11 PKIKLNNGHLIPQLGLGVWKA------SLAETQQMVKEAIMNDYVLIDTAKQYGNEAAVG 64
Query: 278 QGIAEAIANGLVTREELFVTTKLWN-DKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA 454
QGI + R+ +F+TTK++N D+ D++ A+ E LKKL +Y+DL L+H+P+
Sbjct: 65 QGIQDGFKATGRKRDSIFLTTKIFNGDQGDYDKLRQAVNEQLKKLQTNYVDLLLLHWPVN 124
Query: 455 TKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVN 634
K Y E+W+ ++D + G A++IGV NFN ++T L+ ++ I+P INQIE N
Sbjct: 125 DK---------YNESWRALEDIYKDGQAKAIGVCNFNVERMTDLLDHAKIKPAINQIEFN 175
Query: 635 PTNTQEPLXAHCXSLGIAVMAYSPFG 712
P Q + C I + A+SP G
Sbjct: 176 PLIHQPKIVKFCRENDIQLEAWSPLG 201
>UniRef50_Q5FK99 Cluster: Oxidoreductase aldo-keto reductase family;
n=5; Lactobacillus|Rep: Oxidoreductase aldo-keto
reductase family - Lactobacillus acidophilus
Length = 289
Score = 121 bits (292), Expect = 2e-26
Identities = 78/204 (38%), Positives = 111/204 (54%)
Frame = +2
Query: 98 PCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 277
P I+L+ G +P + G G + S+ V+ AV AI GYR IDTA Y ++ VG
Sbjct: 5 PKIKLNDGNEIPQL----GFGVFQISNHDEAVK-AVESAISNGYRLIDTAEAYNNQTAVG 59
Query: 278 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 457
EAI N V R+++F+TTKLW ++ A+ E LK+LG DYID+ L+H
Sbjct: 60 ----EAIKNSDVNRDDIFLTTKLWVSNFTYEKASKAIDEDLKELGTDYIDMMLLHQAYG- 114
Query: 458 KPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNP 637
D W+ ++DA++ G +SIGVSNF Q+ L S ++PV+NQIEVNP
Sbjct: 115 ---------DVAGAWRALEDAQKAGKTKSIGVSNFWPDQLMNLQLMSNVKPVVNQIEVNP 165
Query: 638 TNTQEPLXAHCXSLGIAVMAYSPF 709
+EP +AV A++PF
Sbjct: 166 WFQREPEVKWNQKDDVAVEAWAPF 189
>UniRef50_Q6U5V3 Cluster: Putative uncharacterized protein; n=1;
Klebsiella pneumoniae|Rep: Putative uncharacterized
protein - Klebsiella pneumoniae
Length = 279
Score = 121 bits (291), Expect = 2e-26
Identities = 64/167 (38%), Positives = 103/167 (61%)
Frame = +2
Query: 212 AIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQ 391
A++AG+RH DTA Y +E+ VG+ A+ V RE+LF+T+K+ + + +
Sbjct: 36 ALKAGFRHFDTAQAYFNEDGVGR----ALRYTEVPREQLFITSKIRGRDMGYARTLVSFN 91
Query: 392 ESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNAT 571
E+L++LG++Y++L+LIH+PI K N+ Y+ETW+ + GL RSIGVSNF
Sbjct: 92 ETLERLGVEYLELFLIHWPIPAK------NL-YVETWEASIELEASGLIRSIGVSNFTCQ 144
Query: 572 QITRLVSNSYIRPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
I RL+ ++ + P +NQ+E++P Q + + GIA+ +YSPFG
Sbjct: 145 HIERLIEDTGVVPAVNQLELHPHFQQCDVRDYHHEAGIAIQSYSPFG 191
>UniRef50_Q54NR2 Cluster: Aldo-keto reductase; n=3; Dictyostelium
discoideum AX4|Rep: Aldo-keto reductase - Dictyostelium
discoideum AX4
Length = 305
Score = 121 bits (291), Expect = 2e-26
Identities = 72/193 (37%), Positives = 111/193 (57%), Gaps = 10/193 (5%)
Frame = +2
Query: 152 GRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIA--NGL----V 313
G GT K +D + + +E GYR IDTA++Y +EE++G+ + E + +GL +
Sbjct: 31 GIGTFKLND----IENIIKVGLENGYRRIDTASMYNNEERIGKVLNEMVTKNDGLDGKKI 86
Query: 314 TREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPD--DSPDNID 487
RE+LF+T+K + + + A + SLKKL LDY+D YLIH+P D DS ++I
Sbjct: 87 KREDLFITSKCSFMEQGYENALKAFESSLKKLQLDYLDCYLIHWPGVKGLDGSDSGNSIQ 146
Query: 488 YLETWQGMQDARQLGLARSIGVSNFNATQITRLVS--NSYIRPVINQIEVNPTNTQEPLX 661
+TW+ ++ Q RSIGVSN+ +T L+S N I+P INQ+E +P N Q+ L
Sbjct: 147 RAQTWRALEKLYQDKKVRSIGVSNYTINHLTELLSSPNLQIKPAINQVEFHPLNFQKDLL 206
Query: 662 AHCXSLGIAVMAY 700
C + I + +Y
Sbjct: 207 EFCKNNKIILESY 219
>UniRef50_UPI00015B40FA Cluster: PREDICTED: similar to CG2767-PA;
n=2; Nasonia vitripennis|Rep: PREDICTED: similar to
CG2767-PA - Nasonia vitripennis
Length = 356
Score = 120 bits (290), Expect = 3e-26
Identities = 77/217 (35%), Positives = 117/217 (53%), Gaps = 14/217 (6%)
Frame = +2
Query: 104 IQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 283
I+L +G +P + LGT + + + AV A+E+GYRHIDTA Y +EE +G+
Sbjct: 28 IKLSSGHDMPMIGLGTWQMPPEA------IEVAVTAALESGYRHIDTAFTYGNEEAIGKT 81
Query: 284 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 463
+ + G RE+LF+TTKL + V L+ SL+KLGL+Y+++YLIH P A
Sbjct: 82 LKKWFDKG-GKREDLFITTKLPPIGMRAEYVESYLKLSLEKLGLEYVNMYLIHKPFAFVK 140
Query: 464 DD-------SPD-------NIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSY 601
D +PD + D++ W+ M+ + G RSIG+SNFN +Q+ + ++
Sbjct: 141 DKYKYEPALNPDGSVVLDTDTDHVAIWRAMEKQVKAGRVRSIGLSNFNKSQLLNVYEHAE 200
Query: 602 IRPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
I+P QIE+ N Q P+ C I V A+S G
Sbjct: 201 IKPSNLQIELQAYNQQRPMRELCAERNITVTAFSTLG 237
>UniRef50_UPI00006CCCD7 Cluster: oxidoreductase, aldo/keto reductase
family protein; n=1; Tetrahymena thermophila SB210|Rep:
oxidoreductase, aldo/keto reductase family protein -
Tetrahymena thermophila SB210
Length = 323
Score = 120 bits (290), Expect = 3e-26
Identities = 72/208 (34%), Positives = 113/208 (54%), Gaps = 5/208 (2%)
Frame = +2
Query: 104 IQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 283
+QL+ G +P + LGT ++ + + A++ GYR+ DTA Y++E ++GQ
Sbjct: 15 VQLNNGYKMPLLGLGTQPYDIVTRVTVEEMTTLLSNALDFGYRNFDTAKQYRNEVEIGQA 74
Query: 284 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHF---PIA 454
G RE++F+TTKL+ K + ++ +Q SL +L YIDLYLI + P+
Sbjct: 75 FQNIFQQGKYKREDVFITTKLFPFKIEK-KIKEVVQNSLDQLQTSYIDLYLIQWSFTPVL 133
Query: 455 TKPDDSP--DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIE 628
T D S ++ E W+ +++ +LG+ RSIGV+NFN + L+S + I+PV+NQIE
Sbjct: 134 TNFDGSVAVNHRPIHEVWRELEECVELGMIRSIGVANFNCQMVLDLLSYAKIKPVVNQIE 193
Query: 629 VNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
V P Q L I +A SP G
Sbjct: 194 VTPYLPQIDLINFLKRCKIETVAISPLG 221
>UniRef50_Q890A0 Cluster: Oxidoreductase; n=6; Lactobacillales|Rep:
Oxidoreductase - Lactobacillus plantarum
Length = 282
Score = 120 bits (290), Expect = 3e-26
Identities = 77/208 (37%), Positives = 107/208 (51%)
Frame = +2
Query: 83 MAVQAPCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQD 262
M V QL G +P VA GT + + QAV A+ AGYRHIDTA YQ+
Sbjct: 1 MTVLTTMYQLANGVNIPKVAFGTWQIPGGEA-----TYQAVRAALAAGYRHIDTALAYQN 55
Query: 263 EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIH 442
E VGQ AI + + RE++FVTTKL + + + SLK LGLDY+DLYL+H
Sbjct: 56 EASVGQ----AIRDSGIPREQIFVTTKLPAETKSYQGALNDFDRSLKNLGLDYVDLYLVH 111
Query: 443 FPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQ 622
P + L+ WQ M+ Q G A++IGVSNF + +++ + I P++NQ
Sbjct: 112 APWPWGQVGRVYDEANLDVWQAMEAIYQSGRAKAIGVSNFAVRDLKNILNQATIPPMVNQ 171
Query: 623 IEVNPTNTQEPLXAHCXSLGIAVMAYSP 706
I+ T+ + + V AYSP
Sbjct: 172 IQYYLGFTEPKITKFSEEHAMLVEAYSP 199
>UniRef50_Q5FLI5 Cluster: Aldehyde reductase; n=2; Bacteria|Rep:
Aldehyde reductase - Lactobacillus acidophilus
Length = 278
Score = 120 bits (290), Expect = 3e-26
Identities = 69/202 (34%), Positives = 110/202 (54%)
Frame = +2
Query: 104 IQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 283
+ L+ G +P + G + D + +Q V +E GYR +DTA +Y +E+ VG
Sbjct: 5 VTLNNGIKMPRLGFGVYQ-----IDDLAQAQQVVEDGLEVGYRLVDTAQIYGNEQAVG-- 57
Query: 284 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 463
+AI + V RE++F+T+K+W D + D + A +S+KKL LDYIDLYLIH P
Sbjct: 58 --DAIKHSNVPREDIFITSKIWVDDYGYDNTLKAFDDSMKKLQLDYIDLYLIHKPYN--- 112
Query: 464 DDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTN 643
DY TW+ ++ Q G R+IGVS+F ++ L++ + ++P +NQIE N N
Sbjct: 113 -------DYYGTWRALERLYQEGRIRAIGVSSFWNERLADLITFNDVKPAVNQIETNVWN 165
Query: 644 TQEPLXAHCXSLGIAVMAYSPF 709
+ + G+ A++PF
Sbjct: 166 QEWKSQQYMEKEGVQPEAWAPF 187
>UniRef50_Q1M4Z6 Cluster: Putative aldo-keto reductase/oxidase; n=1;
Rhizobium leguminosarum bv. viciae 3841|Rep: Putative
aldo-keto reductase/oxidase - Rhizobium leguminosarum
bv. viciae (strain 3841)
Length = 274
Score = 120 bits (290), Expect = 3e-26
Identities = 73/177 (41%), Positives = 102/177 (57%), Gaps = 1/177 (0%)
Frame = +2
Query: 179 SIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDK 358
S Q V WA+EAG RHIDTA Y +E+ V +GI +A G V R E+F+TTK+ D
Sbjct: 21 SADEAHQGVIWALEAGCRHIDTAQGYGNEQDVARGIKDA---G-VARNEIFITTKVKPDN 76
Query: 359 HARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLA 538
+ V+P+++ESL+KL +D +DL L+H+P P + DYL + + D+ GLA
Sbjct: 77 YGPGAVMPSVRESLEKLRVDQVDLLLLHWP---SPHNKYPLADYLGQFAEVFDS---GLA 130
Query: 539 RSIGVSNFNATQITRLVSNSYIRPV-INQIEVNPTNTQEPLXAHCXSLGIAVMAYSP 706
R IGVSNF I + R + NQ+E + P+ +C +LGIAV AYSP
Sbjct: 131 RQIGVSNFTKAMIDESIRLLDSRTITTNQVECHVYMQNRPIIDYCQNLGIAVTAYSP 187
>UniRef50_A3LTU8 Cluster: D-arabinose dehydrogenase; n=5;
Saccharomycetales|Rep: D-arabinose dehydrogenase -
Pichia stipitis (Yeast)
Length = 326
Score = 120 bits (290), Expect = 3e-26
Identities = 73/208 (35%), Positives = 113/208 (54%), Gaps = 21/208 (10%)
Frame = +2
Query: 152 GRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELF 331
G GT D +++ V A++AGYRHIDTA Y EE +GQ + + G+V RE+LF
Sbjct: 22 GLGTVPPEDP-HELKEQVITAVKAGYRHIDTAWYYGTEEYIGQALKQLFEEGIVKREDLF 80
Query: 332 VTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA---------TKP------- 463
+TTK+W + +L +SL LGLDY+DL+L H+P+ +P
Sbjct: 81 ITTKVWPSFWRNPE--KSLDKSLADLGLDYVDLFLQHWPVVLHGDENGLPPQPRDKDGKL 138
Query: 464 --DDSP-DNIDYLETWQGMQDAR-QLGLARSIGVSNFNATQITRLVSN-SYIRPVINQIE 628
DD P I Y++ + ++D +SIGVSN++ ++ +L++ +PV+NQIE
Sbjct: 139 IYDDDPVSGIKYIDAYHSLEDIMDNTSKVKSIGVSNYSIPKLRKLLAAVRKHKPVVNQIE 198
Query: 629 VNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+P Q+ L +C G+ + AYSP G
Sbjct: 199 YHPLLPQQDLVKYCYDNGVHISAYSPVG 226
>UniRef50_A3JU52 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=1; Rhodobacterales bacterium HTCC2150|Rep:
2,5-diketo-D-gluconic acid reductase A - Rhodobacterales
bacterium HTCC2150
Length = 334
Score = 120 bits (289), Expect = 4e-26
Identities = 70/171 (40%), Positives = 97/171 (56%), Gaps = 7/171 (4%)
Frame = +2
Query: 212 AIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHA-------RD 370
AI+AGYRHIDTA+ YQ+E+ VG GI + + +TR++LFVT KLW A +
Sbjct: 70 AIQAGYRHIDTASGYQNEKTVGAGIKAGLQSAGITRKDLFVTAKLWPGNPAWGDAPKTKA 129
Query: 371 QVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIG 550
Q + SL +LGLDY+DLYLIH P LE W+ + + + G ARSIG
Sbjct: 130 QTLDECDASLARLGLDYVDLYLIHAPYGGDM--------RLEQWRALLELQANGKARSIG 181
Query: 551 VSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYS 703
VSNFN + + + + P NQIE++P + + L A+ IA +AYS
Sbjct: 182 VSNFNESHLNEIKAAGLPMPDANQIELHPWSQKPDLLAYMDQHAIAPIAYS 232
>UniRef50_Q6RZX1 Cluster: Gld1; n=22; Pezizomycotina|Rep: Gld1 -
Trichoderma atroviride (Hypocrea atroviridis)
Length = 327
Score = 120 bits (288), Expect = 5e-26
Identities = 70/217 (32%), Positives = 113/217 (52%), Gaps = 16/217 (7%)
Frame = +2
Query: 110 LHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 289
L+ G +P V GT ++ V +A ++ GYRH+D A Y +E++VG I
Sbjct: 17 LNTGAKIPAVGFGTFANEGAKGETYAAVTKA----LDVGYRHLDCAWFYLNEDEVGDAIR 72
Query: 290 EAIANGL-VTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPD 466
+ +A VTR++LF+ TK+WN H + V + + S + L +DYIDL+L+H+PIA + +
Sbjct: 73 DFLARRPDVTRKDLFICTKVWNHLHEPEDVKWSAKNSCENLKVDYIDLFLVHWPIAAEKN 132
Query: 467 D------SPDNIDYLE---------TWQGMQDARQLGLARSIGVSNFNATQITRLVSNSY 601
PD + TW+ M++ G+ ++IGVSN+ + +L+ +
Sbjct: 133 ADRTVKIGPDGKYVINKALTENPEPTWRAMEELVDSGIVKAIGVSNWTIPGLKQLLEFAR 192
Query: 602 IRPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
I+P +NQIE++P L C I AYSP G
Sbjct: 193 IKPAVNQIEIHPFLPNTELVEFCFQNDILPEAYSPLG 229
>UniRef50_UPI00015B4912 Cluster: PREDICTED: similar to aldo-keto
reductase; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to aldo-keto reductase - Nasonia vitripennis
Length = 353
Score = 119 bits (287), Expect = 6e-26
Identities = 83/240 (34%), Positives = 127/240 (52%), Gaps = 15/240 (6%)
Frame = +2
Query: 38 VCLLXITFTRLLHAAMAVQAPCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAI 217
+C + I++++ + A + L +G P V LGT D + V A+
Sbjct: 14 LCCVSISYSQNVEAGTVYR-----LSSGHNFPIVGLGTH---GLNEDVLETVLTG---AL 62
Query: 218 EAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKL-WNDKHARDQVVPALQE 394
E G HIDT+ VY++EE +G+ + + A G RE++FVT+KL + D H + V ++
Sbjct: 63 EKGIGHIDTSFVYKNEETIGKVLKDWFAKG-GKREDIFVTSKLPYYDNHP-ESVEKYIKL 120
Query: 395 SLKKLGLDYIDLYLIHFP-----------IATKPDDS---PDNIDYLETWQGMQDARQLG 532
SL+KLGL Y+D+YLIH P +AT D S D + W+ M+ + G
Sbjct: 121 SLEKLGLQYLDMYLIHAPFAVHHKEDSYELATNEDGSVVLDTQTDPIAVWKEMEKQVKEG 180
Query: 533 LARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+SIG+SNFN TQIT ++ + I+P Q+EV+ + Q+PL C GI V Y+P G
Sbjct: 181 RTKSIGLSNFNETQITNILKEAKIKPSNLQVEVHAYHQQKPLIEFCQKNGIIVTGYAPLG 240
>UniRef50_Q03PG5 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=1; Lactobacillus brevis ATCC
367|Rep: Aldo/keto reductase of diketogulonate reductase
family - Lactobacillus brevis (strain ATCC 367 / JCM
1170)
Length = 268
Score = 119 bits (286), Expect = 9e-26
Identities = 73/202 (36%), Positives = 109/202 (53%)
Frame = +2
Query: 107 QLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGI 286
QL G +P + GT +K V A+ A++AGYRH+D A +Y +E VG+ I
Sbjct: 5 QLSNGVTIPMLGFGTYLIDSKD------VPAAIKTALDAGYRHLDCAHIYGNEPAVGEAI 58
Query: 287 AEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPD 466
A+G + R +LF+T+K+WN D+ + A ++L L LDY+DLYLIH+P D
Sbjct: 59 K---ASG-IDRSDLFITSKVWNADQGYDKTLAAFDQTLSDLQLDYLDLYLIHWP---NED 111
Query: 467 DSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNT 646
D +D TW+ ++ Q R+IGVSNF+ Q+ ++ + ++P+INQIE +P
Sbjct: 112 DFELTLD---TWRVLETLYQQKKVRAIGVSNFSEDQLKQVFEMATVKPMINQIERHPYKV 168
Query: 647 QEPLXAHCXSLGIAVMAYSPFG 712
Q L I YSP G
Sbjct: 169 QADLGQFDTDNDIVNEGYSPIG 190
>UniRef50_Q2U219 Cluster: Aldo/keto reductase family proteins; n=6;
Pezizomycotina|Rep: Aldo/keto reductase family proteins
- Aspergillus oryzae
Length = 294
Score = 119 bits (286), Expect = 9e-26
Identities = 75/206 (36%), Positives = 113/206 (54%), Gaps = 3/206 (1%)
Frame = +2
Query: 98 PCIQLHAGXPLPXVALGTGRGTAKXS--DSIXX-VRQAVYWAIEAGYRHIDTAAVYQDEE 268
P ++L+ +P + GTG K + DS+ + +A+ AI GYRH+D A VY E
Sbjct: 10 PRVKLNDNVSIPILGYGTGTAWYKQAGDDSVNRELVEAIKTAIRLGYRHLDGAEVYGTEA 69
Query: 269 QVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFP 448
++G I E+ G + REELFVTTK+ + + A+ +SL+KL L+Y+DLYLIH P
Sbjct: 70 ELGVAIKES---G-IPREELFVTTKVITNIA---DIPSAIDQSLRKLQLNYVDLYLIHSP 122
Query: 449 IATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIE 628
K D + + W M+ +Q G A++IGVSN++ + + + + I PVINQIE
Sbjct: 123 FFAKSDG-----ELQQAWAAMEKVQQAGKAKAIGVSNYHQSHLEATLKTAVIAPVINQIE 177
Query: 629 VNPTNTQEPLXAHCXSLGIAVMAYSP 706
+P QE L I + +Y P
Sbjct: 178 HHPYLQQEELLRFQREKDIKIASYGP 203
>UniRef50_A7ALH6 Cluster: Putative uncharacterized protein; n=1;
Parabacteroides merdae ATCC 43184|Rep: Putative
uncharacterized protein - Parabacteroides merdae ATCC
43184
Length = 301
Score = 118 bits (285), Expect = 1e-25
Identities = 78/207 (37%), Positives = 112/207 (54%)
Frame = +2
Query: 92 QAPCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQ 271
+ P ++L+ G +P + G GT D+ + V AI+ G+R IDTA Y +E++
Sbjct: 28 KVPTVKLNNGMEMPQL----GVGTFLVKDNAA---ERVCHAIKVGFRLIDTAQGYGNEKE 80
Query: 272 VGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPI 451
VG+GI + G + R ELF+TTK+ + V +L +SL LG DYIDL LIH+P+
Sbjct: 81 VGEGICRS---G-IDRRELFITTKVNTMEMRGGTVRQSLDKSLADLGTDYIDLVLIHWPV 136
Query: 452 ATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEV 631
ETWQ +++ G RSIGVSNFN + L+ + IRPV+NQIE+
Sbjct: 137 KGH---------IKETWQILEEYVDKGKIRSIGVSNFNPHHLDELLEYARIRPVVNQIEI 187
Query: 632 NPTNTQEPLXAHCXSLGIAVMAYSPFG 712
P TQ + + GI V A+ P G
Sbjct: 188 EPYMTQHDVVGYTFRKGIQVEAWGPLG 214
>UniRef50_Q5FT75 Cluster: Putative 2,5-diketo-D-gluconic acid
reductase; n=1; Gluconobacter oxydans|Rep: Putative
2,5-diketo-D-gluconic acid reductase - Gluconobacter
oxydans (Gluconobacter suboxydans)
Length = 279
Score = 118 bits (284), Expect = 2e-25
Identities = 68/203 (33%), Positives = 109/203 (53%)
Frame = +2
Query: 104 IQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 283
I H G +P + LG ++ V++AV + GYR +DTA +Y++EE VG+G
Sbjct: 14 ISFHDGHTMPQIGLGVWE--TPPDETAEVVKEAV----KLGYRSVDTARLYKNEEGVGKG 67
Query: 284 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 463
+ + E+F+TTKLWND+ D + A +ES + L +DLYLIH+P+
Sbjct: 68 LED--------HPEIFLTTKLWNDEQGYDSTLRAYEESARLLRRPVLDLYLIHWPM---- 115
Query: 464 DDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTN 643
P Y+ETW+ + + ++ G +SIGVSNF + + R++ + + PV+NQIE++P
Sbjct: 116 ---PAQGQYVETWKALVELKKSGRVKSIGVSNFESEHLERIMDATGVVPVVNQIELHPDF 172
Query: 644 TQEPLXAHCXSLGIAVMAYSPFG 712
Q L I ++ P G
Sbjct: 173 QQRALREFHEKHNIRTESWRPLG 195
>UniRef50_Q11BF8 Cluster: Aldo/keto reductase; n=12; Bacteria|Rep:
Aldo/keto reductase - Mesorhizobium sp. (strain BNC1)
Length = 308
Score = 118 bits (283), Expect = 2e-25
Identities = 68/171 (39%), Positives = 98/171 (57%)
Frame = +2
Query: 200 AVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVV 379
AV A+ GYRHIDTAA Y +E +VG+GI A G + R+E+F+ TK+W + D+ +
Sbjct: 47 AVEEALRLGYRHIDTAAAYGNEREVGEGIRRA---G-IARDEVFIETKIWISDYGYDETL 102
Query: 380 PALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSN 559
A +S KLG+D IDL L+H P+ + D + L ++ ++ G R+IGVSN
Sbjct: 103 HAFDKSAGKLGVDQIDLLLLHQPLPSAFDRT------LGAYRALEKLLADGKVRAIGVSN 156
Query: 560 FNATQITRLVSNSYIRPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
F +TRL++ + I P +NQIEV+P Q L GI A+SP G
Sbjct: 157 FMPEHLTRLLTETSIVPAVNQIEVHPYFQQRALQRLHAEHGILTQAWSPIG 207
>UniRef50_Q5BLA6 Cluster: Zgc:110782; n=2; Danio rerio|Rep:
Zgc:110782 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 287
Score = 117 bits (282), Expect = 3e-25
Identities = 72/207 (34%), Positives = 111/207 (53%), Gaps = 2/207 (0%)
Frame = +2
Query: 98 PCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 277
P ++L +G +P + LGT K D ++Q+V A++AGYR DTAAVY +E +G
Sbjct: 4 PSVRLMSGTQMPLLGLGT----YKLQDH-EQLKQSVSCALQAGYRAFDTAAVYGNEAHLG 58
Query: 278 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFP--I 451
Q + E + + RE++F+ +KL H L+ SL++L +YIDLYLIH+P
Sbjct: 59 QVLKELLPKYGLIREDVFIISKLAPSDHGLRAKEGCLR-SLEQLDCEYIDLYLIHWPGME 117
Query: 452 ATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEV 631
P+DS + ++W +++ G ++IGVSN+ A I L+++ + P + QIE
Sbjct: 118 GLDPEDSRHSEYRAQSWATLEEFHASGQFKAIGVSNYTAKHIRELLASCRVPPAVLQIEC 177
Query: 632 NPTNTQEPLXAHCXSLGIAVMAYSPFG 712
P Q L C GI AYS G
Sbjct: 178 QPKLIQRELRDLCMETGIHFQAYSSLG 204
>UniRef50_A6LZ55 Cluster: 2,5-didehydrogluconate reductase; n=1;
Clostridium beijerinckii NCIMB 8052|Rep:
2,5-didehydrogluconate reductase - Clostridium
beijerinckii NCIMB 8052
Length = 289
Score = 117 bits (282), Expect = 3e-25
Identities = 64/171 (37%), Positives = 94/171 (54%)
Frame = +2
Query: 200 AVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVV 379
AV AI+ GYRH DTA +Y +E+ +G AI + REE F+T+K+WN H +
Sbjct: 35 AVGEAIKIGYRHFDTAKIYGNEKDLGL----AIEKSQIPREEFFITSKVWNTDHGYEATK 90
Query: 380 PALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSN 559
A +++ KKL ++Y+D+YLIHF + YLETW M++ G + IGV+N
Sbjct: 91 KAFEQTCKKLNVEYLDMYLIHFASSY----------YLETWHAMEELYLQGKIKVIGVAN 140
Query: 560 FNATQITRLVSNSYIRPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
F + L+ +S I P+INQIE +P Q L + I A++P G
Sbjct: 141 FQIQHLEELMKHSRITPMINQIETHPEFPQNELHQYLTKHKILHEAWAPLG 191
>UniRef50_A0AWM8 Cluster: Aldo/keto reductase; n=4;
Actinomycetales|Rep: Aldo/keto reductase - Arthrobacter
sp. (strain FB24)
Length = 287
Score = 117 bits (282), Expect = 3e-25
Identities = 73/210 (34%), Positives = 118/210 (56%), Gaps = 1/210 (0%)
Frame = +2
Query: 86 AVQAPCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDE 265
A P ++L G +P + LGT ++ AV +A+++GYR +DTA Y++E
Sbjct: 10 ASDIPRLKLPHGHTIPRLGLGTWPMLEDECET------AVRFALQSGYRLVDTAFQYRNE 63
Query: 266 EQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHF 445
E VG+GI A G V R ELF+++K + H+ D V A ESL+KLGLD++D+++ H+
Sbjct: 64 EAVGRGIRTA---G-VPRSELFISSKFNKESHSIDGVQRAYDESLRKLGLDHLDMFMCHW 119
Query: 446 PIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQI 625
P+ P Y++ W+G+ + G ++IGVSNF + ++ + + P +NQI
Sbjct: 120 PV-------PALGKYVDAWKGLVKLLEEGRVKAIGVSNFKPAHLKDIIDATGVVPDVNQI 172
Query: 626 EVNPTNTQ-EPLXAHCXSLGIAVMAYSPFG 712
+++P + EP H LGI A+SP G
Sbjct: 173 QLSPDLARTEPRAVH-RLLGIVTEAWSPIG 201
>UniRef50_Q89JN4 Cluster: Oxidoreductase; n=8; Rhizobiales|Rep:
Oxidoreductase - Bradyrhizobium japonicum
Length = 272
Score = 117 bits (281), Expect = 3e-25
Identities = 73/196 (37%), Positives = 109/196 (55%)
Frame = +2
Query: 119 GXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAI 298
G +P + LGT + + + V A+ GYRHIDTA VY +E +VG G+
Sbjct: 8 GARIPAIGLGTWELSGRPCARV------VEQALRLGYRHIDTAQVYDNEREVGDGVR--- 58
Query: 299 ANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPD 478
A+G V R+++F+TTK+W + A + + +++ESL +L L +DL L+H+P + P
Sbjct: 59 ASG-VRRDDVFLTTKVWTNHFAPNDLERSVKESLARLRLPSVDLLLLHWPNSHVP----- 112
Query: 479 NIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEPL 658
ET + ARQ+GL R IGVSNF I + V+ S V NQ+E +P Q +
Sbjct: 113 ---LAETLGALSHARQMGLTRHIGVSNFTVALIEQAVALSPEPLVCNQVEFHPYLDQAKV 169
Query: 659 XAHCXSLGIAVMAYSP 706
A C G+A++AYSP
Sbjct: 170 RAACDQHGLALVAYSP 185
>UniRef50_Q03X85 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=1; Leuconostoc mesenteroides subsp.
mesenteroides ATCC 8293|Rep: Aldo/keto reductase of
diketogulonate reductase family - Leuconostoc
mesenteroides subsp. mesenteroides (strain ATCC 8293
/NCDO 523)
Length = 288
Score = 117 bits (281), Expect = 3e-25
Identities = 69/185 (37%), Positives = 101/185 (54%), Gaps = 4/185 (2%)
Frame = +2
Query: 194 RQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQ 373
+QAV AI AGYR IDTA VY +E + GQG+ EAIAN +V REELF+TTKLW + + +
Sbjct: 28 KQAVVDAINAGYRSIDTARVYGNEAETGQGVNEAIANAVVAREELFLTTKLWLSEFSYEA 87
Query: 374 VVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGV 553
A+ +SLKKLG DY DL L+H P D ++ + +A+ G +SIG+
Sbjct: 88 AKGAIDDSLKKLGTDYADLILLHQPYG----------DVYGAYKALAEAQADGKVKSIGI 137
Query: 554 SNFNATQITRLV----SNSYIRPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFGFVV 721
SNF + + + + P I+QIE +P ++ G+ + A+ P G
Sbjct: 138 SNFYPAKFVEFIKVIKTMNLPVPQIDQIEFHPYYQEKVARQLHDKYGVQIEAWGPLGRTA 197
Query: 722 SRGXT 736
++ T
Sbjct: 198 NKYDT 202
>UniRef50_Q9P6D3 Cluster: Related to aldo-keto reductase YPR1; n=10;
Pezizomycotina|Rep: Related to aldo-keto reductase YPR1
- Neurospora crassa
Length = 322
Score = 117 bits (281), Expect = 3e-25
Identities = 77/214 (35%), Positives = 109/214 (50%), Gaps = 11/214 (5%)
Frame = +2
Query: 98 PCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQ----AVYWAIEAGYRHIDTAAVYQDE 265
P ++L G +P + G G K DS + + A A+ AGY H+D A VY +E
Sbjct: 25 PSLKLSDGNEIPMLGYGLGTANYKSGDSADTISEPIVNATLTALNAGYAHLDGAEVYGNE 84
Query: 266 EQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHF 445
++G+ AIA + R L++TTK A D V + SL+KLGLDY+DLYL+H
Sbjct: 85 VELGR----AIAQSKLPRSSLYITTK--TIVRAGDTVTQSFNRSLEKLGLDYVDLYLLHS 138
Query: 446 PIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLV---SNSYIRPVI 616
P K +P+ + W+ M+ + G+A+SIGVSNF + + L PV+
Sbjct: 139 PFFAK---NPEQLQ--AAWREMEKIKDSGMAKSIGVSNFLISHLQTLFDIPGGLQYPPVV 193
Query: 617 NQIEVNP----TNTQEPLXAHCXSLGIAVMAYSP 706
NQIE +P E L A C IA+ AYSP
Sbjct: 194 NQIEYHPYLQHVVEGEDLVAFCREKHIAIAAYSP 227
>UniRef50_Q043M4 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=2; Lactobacillus|Rep: Aldo/keto
reductase of diketogulonate reductase family -
Lactobacillus gasseri (strain ATCC 33323 / DSM 20243)
Length = 273
Score = 116 bits (279), Expect = 6e-25
Identities = 71/187 (37%), Positives = 105/187 (56%)
Frame = +2
Query: 152 GRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELF 331
G GT + S +QAV A E GYR IDTA YQ+E+QVG+ + A+GL R+E+F
Sbjct: 16 GFGTYEISPD--QTKQAVLSAFEEGYRLIDTAQYYQNEQQVGEAVK---ASGL-NRDEVF 69
Query: 332 VTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGM 511
+TTK D + ++ L ESL+++GLDY DL LIH+P+ ++TW +
Sbjct: 70 ITTKTMTDGYEDTKI--GLDESLRRIGLDYFDLVLIHWPMGHD----------IDTWHAL 117
Query: 512 QDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEPLXAHCXSLGIAV 691
+ A + G R+IG+SNFN+ Q L+ S +RP+++QIE + Q + I
Sbjct: 118 EAAYKAGKTRAIGISNFNSRQTLDLIHQSSVRPMVDQIETHLFLQQWKMHEFLEKENIVH 177
Query: 692 MAYSPFG 712
+YSP G
Sbjct: 178 ESYSPLG 184
>UniRef50_A7P424 Cluster: Chromosome chr1 scaffold_5, whole genome
shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
chr1 scaffold_5, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 247
Score = 116 bits (278), Expect = 8e-25
Identities = 65/162 (40%), Positives = 95/162 (58%), Gaps = 11/162 (6%)
Frame = +2
Query: 200 AVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLV-TREELFVTTKLWNDKHARDQV 376
++ AIE GYRH D A Y E+ +G+ I +A+ GL+ +R+ELF+T+KLW D+V
Sbjct: 37 SILTAIELGYRHFDCVAAYLSEKPLGEAIKKAVKLGLIKSRDELFITSKLWCSDAHHDRV 96
Query: 377 VPALQESLK---------KLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQL 529
+PALQ +LK L LDY+DLYLIH+ P ID W+ M+D ++L
Sbjct: 97 LPALQNTLKISSILSFSKNLQLDYLDLYLIHWSDGHLP------IDLGSVWKAMEDFQKL 150
Query: 530 GLARSIGVSNFNATQITRLVSNSYIRPVINQIEVN-PTNTQE 652
L ++IGVSNF+ ++ L+ + I P +NQ+ N PT E
Sbjct: 151 SLTKAIGVSNFSCNKLEELLQTASILPAVNQVSENEPTLAAE 192
>UniRef50_A7BA05 Cluster: Putative uncharacterized protein; n=1;
Actinomyces odontolyticus ATCC 17982|Rep: Putative
uncharacterized protein - Actinomyces odontolyticus ATCC
17982
Length = 292
Score = 115 bits (277), Expect = 1e-24
Identities = 68/203 (33%), Positives = 107/203 (52%)
Frame = +2
Query: 98 PCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 277
P L G P+P + GT + + + AV A+E GYRHIDTA +Y +E +VG
Sbjct: 17 PTFMLPTGSPIPVLGFGTYKVAPEDT------YDAVSRALEVGYRHIDTAQMYGNEAEVG 70
Query: 278 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 457
+ A+G + RE+LF+TTK+ N H D+ +++ SL+ L DY+DL L+H+P+ T
Sbjct: 71 AALE---ASG-IAREDLFITTKVDNSNHEPDRAAASIRRSLEDLRTDYVDLLLVHWPLPT 126
Query: 458 KPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNP 637
D W ++DA G AR+IG+SN+ + + + + P + Q+E +P
Sbjct: 127 LYGG-----DVALPWPALEDAFNAGGARAIGLSNYEREHVEAVREVATVAPHVLQVESHP 181
Query: 638 TNTQEPLXAHCXSLGIAVMAYSP 706
L A+ LG+ A+SP
Sbjct: 182 FFPNADLRAYAQGLGMVFEAWSP 204
>UniRef50_A6RMS0 Cluster: Putative uncharacterized protein; n=1;
Botryotinia fuckeliana B05.10|Rep: Putative
uncharacterized protein - Botryotinia fuckeliana B05.10
Length = 286
Score = 115 bits (277), Expect = 1e-24
Identities = 82/216 (37%), Positives = 112/216 (51%), Gaps = 6/216 (2%)
Frame = +2
Query: 83 MAVQAPCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQD 262
MA +L G LP + LGT +G D V+ V AI+AGYRHID AA Y +
Sbjct: 1 MATPTASFRLVNGSTLPAIGLGTFQG----DDGNEKVKNIVKAAIQAGYRHIDGAAAYGN 56
Query: 263 EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIH 442
EE +G I E+ G ++R+EL + W H V AL SL+ LGL+Y+
Sbjct: 57 EEAIGDAIKES---G-ISRDEL---AQPW---HEPKDVERALDLSLEALGLEYV------ 100
Query: 443 FPIATKPDDSPDNIDY------LETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI 604
P A P P+N+DY ETWQ M+ G A++IG+SNFN + R++ + I
Sbjct: 101 -PHAYLP--GPNNVDYERSRKYTETWQAMEKLVDSGKAKAIGLSNFNILKTKRILEIARI 157
Query: 605 RPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
RP +NQ+E +P Q L A C I +MA+ P G
Sbjct: 158 RPAVNQVEAHPYFPQHELLAFCEKEHIHLMAHQPLG 193
>UniRef50_A3UJS6 Cluster: Oxidoreductase; n=3;
Alphaproteobacteria|Rep: Oxidoreductase - Oceanicaulis
alexandrii HTCC2633
Length = 275
Score = 115 bits (276), Expect = 1e-24
Identities = 68/185 (36%), Positives = 100/185 (54%)
Frame = +2
Query: 152 GRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELF 331
G GT + D + V A++ GYRHIDTA +Y +E VG G ++ G V RE+ F
Sbjct: 16 GFGTWQLEDE--DAARGVATALKTGYRHIDTAQIYGNEAAVGDGWKQS---G-VKREDFF 69
Query: 332 VTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGM 511
+TTK+W DK + +++ESL KL DY+DL L+H+P+ P ET + M
Sbjct: 70 LTTKVWRDKFRDGDLQASVKESLDKLKTDYVDLLLLHWPVPEVP--------IAETMKAM 121
Query: 512 QDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEPLXAHCXSLGIAV 691
+ ++ G R IGVSNF + ++S V NQ+E +P Q + C + G+A+
Sbjct: 122 NEVKEAGQVRHIGVSNFTVDLLDEARAHSGAPLVANQVEYHPYLDQNAVLTACRAAGMAM 181
Query: 692 MAYSP 706
AYSP
Sbjct: 182 TAYSP 186
>UniRef50_Q4PHK0 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 355
Score = 106 bits (255), Expect(2) = 2e-24
Identities = 67/171 (39%), Positives = 96/171 (56%), Gaps = 13/171 (7%)
Frame = +2
Query: 239 DTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLD 418
D A +Y +E +VGQGI A+G V R ELFVTTK+W H + + L ESL++LGLD
Sbjct: 80 DAAWIYGNENEVGQGIK---ASG-VPRSELFVTTKIWCTYHRQPEA--CLDESLQRLGLD 133
Query: 419 YIDLYLIHFPIA-TKPDDS--PDNIDYL----------ETWQGMQDARQLGLARSIGVSN 559
Y+DL L+H+P+ K D P N D +TW+ M+ G ++IGVSN
Sbjct: 134 YVDLLLVHWPVPLVKRGDEKIPLNEDGSRAIDRDWSPEQTWELMEKLPATGKTKAIGVSN 193
Query: 560 FNATQITRLVSNSYIRPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
++ + +L++ + I P NQ+E++P Q L +C GI AYSP G
Sbjct: 194 WSIAFLDKLLAKAKIVPAANQVELHPFLPQHELVKYCHDKGILPQAYSPLG 244
Score = 29.1 bits (62), Expect(2) = 2e-24
Identities = 17/44 (38%), Positives = 24/44 (54%)
Frame = +2
Query: 107 QLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHI 238
+L+ G +P + LGT + V +AV AI+AGYRHI
Sbjct: 15 KLNTGAEIPVIGLGTWQSAP------GEVAKAVESAIKAGYRHI 52
>UniRef50_Q75E75 Cluster: ABL209Cp; n=1; Eremothecium gossypii|Rep:
ABL209Cp - Ashbya gossypii (Yeast) (Eremothecium
gossypii)
Length = 310
Score = 114 bits (275), Expect = 2e-24
Identities = 72/204 (35%), Positives = 110/204 (53%), Gaps = 4/204 (1%)
Frame = +2
Query: 107 QLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGI 286
+L G +P V LG + + + V+ VY A+E GYR D+A Y +E+ V +GI
Sbjct: 14 RLSDGTQIPSVGLGVYQVSEQT------VQDLVYEALEVGYRLFDSAQAYHNEDGVARGI 67
Query: 287 AEAIANGLVTR-EELFVTTKLWNDKHARDQVVPALQESLKKLG-LDYIDLYLIHFPIATK 460
A + + R E+++ TTK+ H + +L++SL G L YIDL L+H P++
Sbjct: 68 AAWLKHAPGRRREDVYFTTKINTQNHGYEATKKSLEKSLHAAGPLGYIDLVLVHAPMS-- 125
Query: 461 PDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVS--NSYIRPVINQIEVN 634
D L TWQ +++A G RSIGVSN+ ++ L+ IRPV+NQ+E+N
Sbjct: 126 -----DRTRRLGTWQALEEAVVEGQVRSIGVSNYGQQHLSELLGWEGLKIRPVVNQVEIN 180
Query: 635 PTNTQEPLXAHCXSLGIAVMAYSP 706
P ++ L +C IAV A+SP
Sbjct: 181 PWLCRQELVQYCRENNIAVQAFSP 204
>UniRef50_Q5FKI1 Cluster: Reductase-dehydrogenase; n=1;
Lactobacillus acidophilus|Rep: Reductase-dehydrogenase -
Lactobacillus acidophilus
Length = 271
Score = 113 bits (273), Expect = 3e-24
Identities = 77/202 (38%), Positives = 103/202 (50%), Gaps = 3/202 (1%)
Frame = +2
Query: 110 LHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 289
L+ G +P + LGT + + VRQAV GYR DTA Y +E VG+GI
Sbjct: 9 LNNGEKIPQIQLGTWLINNDEVNKV--VRQAV----NIGYRGFDTAKDYGNESGVGKGIW 62
Query: 290 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFP---IATK 460
N + R ++F+TTKL + A+ +L K GL+YIDL LIH P I
Sbjct: 63 ----NSDIERSDIFLTTKLPTAVKDYEGTKKAIDAALDKFGLEYIDLLLIHSPQPWIEVN 118
Query: 461 PDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPT 640
+ LE W+ M++A + G RSIGVSNF I +V+N I P +NQIEV+
Sbjct: 119 RTNDRHFKGNLENWRAMEEAVKAGKVRSIGVSNFLQEDIENIVNNGTITPAVNQIEVHIG 178
Query: 641 NTQEPLXAHCXSLGIAVMAYSP 706
L +C LGI + AYSP
Sbjct: 179 KVPVELMDYCKKLGIKIEAYSP 200
>UniRef50_A3VRL4 Cluster: Putative uncharacterized protein; n=1;
Parvularcula bermudensis HTCC2503|Rep: Putative
uncharacterized protein - Parvularcula bermudensis
HTCC2503
Length = 278
Score = 113 bits (273), Expect = 3e-24
Identities = 71/194 (36%), Positives = 105/194 (54%)
Frame = +2
Query: 131 PXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGL 310
P LG G + D+ R A IE GYRHID AA+Y++E++VG+GI ++ G
Sbjct: 10 PIPRLGFGTWQLEGEDARTSTRTA----IETGYRHIDGAAIYKNEKKVGEGIKDS---G- 61
Query: 311 VTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDY 490
+ R+ELFVTTK+WN+ + + A+ ESL +LGLDY++L L+H+PI P D +
Sbjct: 62 IPRDELFVTTKIWNEDIQKGRHSEAVDESLDRLGLDYVNLILLHWPINDMP--IADQVGP 119
Query: 491 LETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEPLXAHC 670
L + ++ G A+ IG+SN+N Q VS S Q E +P Q+P+
Sbjct: 120 L------AEIKRSGRAKLIGISNYNQAQFLEAVSASEEPLAAIQCEYHPMLDQDPILKTA 173
Query: 671 XSLGIAVMAYSPFG 712
+ +YSP G
Sbjct: 174 RGFDMMFTSYSPLG 187
>UniRef50_Q8ZH36 Cluster: 2,5-diketo-D-gluconic acid reductase B;
n=91; Proteobacteria|Rep: 2,5-diketo-D-gluconic acid
reductase B - Yersinia pestis
Length = 267
Score = 113 bits (272), Expect = 4e-24
Identities = 69/189 (36%), Positives = 105/189 (55%), Gaps = 1/189 (0%)
Frame = +2
Query: 152 GRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELF 331
G GT + D I V +V A+ GYR IDTA +Y++E VGQ I E+ N R+ELF
Sbjct: 7 GLGTFRLQDQI--VIDSVSQALTLGYRAIDTAQIYENEAPVGQAIQESGIN----RDELF 60
Query: 332 VTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGM 511
+TTK+W ++D+++P+L+ES++KL DY+DL LIH+P P+ D + E +
Sbjct: 61 ITTKIWIANLSKDKLIPSLRESIQKLKTDYVDLTLIHWP---SPN---DEVSVAEFMSEL 114
Query: 512 QDARQLGLARSIGVSNFNATQITRLVSNSYIRPV-INQIEVNPTNTQEPLXAHCXSLGIA 688
A+ LGL R IG+SNF + + ++ + NQIE++P + GIA
Sbjct: 115 LKAKGLGLTRQIGISNFTIDLMKQAIAAVGAEEIATNQIELSPLLQNRNVVDFAKQNGIA 174
Query: 689 VMAYSPFGF 715
V +Y +
Sbjct: 175 VTSYMTLAY 183
>UniRef50_UPI0000D56CE5 Cluster: PREDICTED: similar to CG6084-PA,
isoform A; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to CG6084-PA, isoform A - Tribolium castaneum
Length = 493
Score = 113 bits (271), Expect = 6e-24
Identities = 62/170 (36%), Positives = 101/170 (59%)
Frame = +2
Query: 203 VYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVP 382
V + + YR +D +++++E++ G + + I G + R++LF+ +K + + V
Sbjct: 36 VQLVVSSNYRLMD-CSIFENEKRFGVALQQLIEGGKIRRKDLFLMSKFCCT-NTTNLVKA 93
Query: 383 ALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNF 562
AL ++LKKL + Y+DLYLI P A K + +ETW+ M+ L R+IG+SNF
Sbjct: 94 ALLDTLKKLQVAYLDLYLIERPPACKDHN------LIETWEAMEGLYSEKLTRAIGLSNF 147
Query: 563 NATQITRLVSNSYIRPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
N+ QI R++ N IRP +NQI+ +P Q L +C + GIAV++YSP G
Sbjct: 148 NSKQIERILENCTIRPQVNQIQCHPYLNQAKLRKYCSNNGIAVISYSPLG 197
Score = 102 bits (245), Expect = 8e-21
Identities = 52/119 (43%), Positives = 72/119 (60%), Gaps = 12/119 (10%)
Frame = +2
Query: 392 ESLKKLGLDYIDLYLIHFPIATKPDDS------------PDNIDYLETWQGMQDARQLGL 535
ESLK L LDY+D+YL+H+P A K S P ++D+++TW+ M+ + L
Sbjct: 271 ESLKNLQLDYLDVYLMHWPHALKEGPSLHPIDPKTGLFIPSDVDFVDTWKAMEKMHEKDL 330
Query: 536 ARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+SIG+SNFN+ QI RL+ ++ I PVINQIE +P Q L C GI V +YSP G
Sbjct: 331 TKSIGISNFNSNQIDRLLKSAKIAPVINQIECHPYLNQSKLRKFCSDRGITVTSYSPLG 389
>UniRef50_Q7VG53 Cluster: Aldo-keto reductase; n=28; Bacteria|Rep:
Aldo-keto reductase - Helicobacter hepaticus
Length = 292
Score = 113 bits (271), Expect = 6e-24
Identities = 74/203 (36%), Positives = 107/203 (52%), Gaps = 4/203 (1%)
Frame = +2
Query: 110 LHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 289
L+ G +P + LGT R D++ V AV A + GYRHIDTA Y +E +G+
Sbjct: 17 LNNGNKIPKLGLGTWR----IDDNV--VEAAVREAFKVGYRHIDTAQAYGNE----RGVG 66
Query: 290 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDD 469
EA+ + REELF+T+K+ + ++ SLK + LD+IDL LIH P +P +
Sbjct: 67 EAVRKSKIKREELFITSKIRAEYKDYKSASASIDTSLKTMKLDFIDLMLIHSP---QPWN 123
Query: 470 SPDNIDY----LETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNP 637
S DY +E + ++DA++ G RSIGVSNF + ++ N +P NQI +
Sbjct: 124 SFRKGDYFKENVEVYNALEDAQKAGKVRSIGVSNFLQKDLENILKNCKTKPAANQILCHI 183
Query: 638 TNTQEPLXAHCXSLGIAVMAYSP 706
NT L +C I AYSP
Sbjct: 184 GNTPFTLLDYCKKQNILAEAYSP 206
>UniRef50_Q5TNP1 Cluster: ENSANGP00000029046; n=2; Culicidae|Rep:
ENSANGP00000029046 - Anopheles gambiae str. PEST
Length = 331
Score = 112 bits (269), Expect = 1e-23
Identities = 73/233 (31%), Positives = 120/233 (51%), Gaps = 16/233 (6%)
Frame = +2
Query: 62 TRLLHAAMAVQA--PCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRH 235
TR + ++ V+ +L+ G +P GT + + + Q + +A+EAGYRH
Sbjct: 18 TRFFNRSVEVKTMNKTFKLNTGFDIPLAGFGTYQIHGQE-----LIYQVLDYALEAGYRH 72
Query: 236 IDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPAL-QESLKKLG 412
IDTA VY++EE +G + + + RE++F+T+KL + + V + ++SL L
Sbjct: 73 IDTAVVYRNEEYIGTALKTLLPKYNLKREDIFITSKLISQSGKDEAFVEQMVRKSLANLQ 132
Query: 413 LDYIDLYLIHFP-IATK----------PDDSPDNIDY-LETWQGMQDARQLGLARSIGVS 556
DY+DLYLIH+P ++ K PDN+ Y +W + + G RSIGVS
Sbjct: 133 TDYLDLYLIHWPGVSGKCGRWKWLFGMQVTHPDNVKYRAASWNALSKLEREGCLRSIGVS 192
Query: 557 NFNATQITRLVSN-SYIRPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
N+ + ++++ I P +NQ+E +P Q L +C GI + AYS G
Sbjct: 193 NYTVKHLKEMLADCKGIVPAVNQVEWHPYYYQPELLEYCRQHGIFLQAYSSLG 245
>UniRef50_Q5K8C5 Cluster: Aldo-keto reductase, putative; n=1;
Filobasidiella neoformans|Rep: Aldo-keto reductase,
putative - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 303
Score = 112 bits (269), Expect = 1e-23
Identities = 66/201 (32%), Positives = 104/201 (51%)
Frame = +2
Query: 104 IQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 283
+++H G +P LG K + V WA+EAGYRH+DTA Y++E G+
Sbjct: 33 LKMHDGNAIPQFGLGVYEMNDKET------YDCVKWALEAGYRHVDTAEWYENEAPCGKA 86
Query: 284 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 463
IA+ + +REE+F+T+KL N+ + +Q L+ SLK+ G++Y DLYL+H I
Sbjct: 87 IADFLKATGTSREEIFLTSKLKNNS-SYEQAFVDLKGSLKRSGVEYFDLYLMHSAIG--- 142
Query: 464 DDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTN 643
P + W+ + DA+ GL +SIGVSNF I + P +NQ++++P
Sbjct: 143 --GP--VIRKNVWKALCDAQSQGLVKSIGVSNFGKKHIQEFIDQKVPLPTVNQVDLHPFM 198
Query: 644 TQEPLXAHCXSLGIAVMAYSP 706
+ C I + A+ P
Sbjct: 199 RHPEIVEICEQNEILLEAWGP 219
>UniRef50_Q1DLF1 Cluster: Putative uncharacterized protein; n=1;
Coccidioides immitis|Rep: Putative uncharacterized
protein - Coccidioides immitis
Length = 324
Score = 112 bits (269), Expect = 1e-23
Identities = 75/198 (37%), Positives = 104/198 (52%), Gaps = 11/198 (5%)
Frame = +2
Query: 152 GRGTAKXSDSIX---XVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTRE 322
G GT + S+ V+ +V A++ GYRHID A Y V +GI AI V RE
Sbjct: 20 GLGTFQVDPSLYPEGSVKDSVLHALKIGYRHIDAALAY-GWGSVERGIGAAIRASGVPRE 78
Query: 323 ELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLI---HFPIATKPDDSPD-NID- 487
++FV TKL N HA + V + SLK LGL Y+ ++ KPD P +I+
Sbjct: 79 DVFVVTKLHNCFHAPEDVEVGMNMSLKNLGLGYVPYAYTKGENYSTVRKPDGKPVVDIEL 138
Query: 488 ---YLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEPL 658
+ TW+ M++ G A+ IGVSNF+ ++ RL+S I PV+NQ+E+NP Q+ L
Sbjct: 139 SRAFDTTWKAMENLVDQGKAKLIGVSNFSTPKLKRLLSVCRIFPVVNQVELNPYFPQKQL 198
Query: 659 XAHCXSLGIAVMAYSPFG 712
C I V AY P G
Sbjct: 199 LRFCHEHEIHVTAYGPLG 216
>UniRef50_Q572D2 Cluster: Aldo-keto reductase, putative; n=1;
Phytophthora infestans|Rep: Aldo-keto reductase,
putative - Phytophthora infestans (Potato late blight
fungus)
Length = 255
Score = 111 bits (268), Expect = 1e-23
Identities = 66/192 (34%), Positives = 106/192 (55%)
Frame = +2
Query: 83 MAVQAPCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQD 262
M+V P L +G +P + LG + S+ A+ +++ GYRHIDTA +Y +
Sbjct: 1 MSVNVPTKILPSGARIPMIGLGVYQ-----SEPGPETYNAILTSLKLGYRHIDTAEIYGN 55
Query: 263 EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIH 442
EE VG+ A+ + + REE+FVTTKL+ + + A + S +LG+ YI LYL+H
Sbjct: 56 EEDVGR----AVRDSGIPREEIFVTTKLFTTNWGYSKALAAGKASNDRLGIVYIYLYLLH 111
Query: 443 FPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQ 622
P K + +TW+ ++D R+ R IGVSNFN T + L ++I+P +NQ
Sbjct: 112 APGPPK--------ERADTWRAVEDLREQETLRDIGVSNFNETLLATLRKTAHIKPAVNQ 163
Query: 623 IEVNPTNTQEPL 658
+E++P ++ L
Sbjct: 164 VELHPWMMRQSL 175
>UniRef50_Q7XY49 Cluster: Mannose 6-phosphate reductase; n=1;
Griffithsia japonica|Rep: Mannose 6-phosphate reductase
- Griffithsia japonica (Red alga)
Length = 174
Score = 99.5 bits (237), Expect(2) = 2e-23
Identities = 50/110 (45%), Positives = 71/110 (64%)
Frame = +2
Query: 110 LHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 289
L +G +P GT + S+ QAV A+ AGYRHID AAVY +E VG I+
Sbjct: 8 LQSGAKMPLNGFGTWKA------SVEETEQAVTAALRAGYRHIDCAAVYWNEAAVGTAIS 61
Query: 290 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLI 439
+AI+ G+V RE+LF+T+K+WN HA D+VV + ++SLK +DY DL+L+
Sbjct: 62 KAISGGVVKREDLFITSKVWNTCHATDKVVDSCRQSLKDHQVDYFDLFLV 111
Score = 33.1 bits (72), Expect(2) = 2e-23
Identities = 17/57 (29%), Positives = 28/57 (49%)
Frame = +2
Query: 515 DARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEPLXAHCXSLGI 685
D L L R IGVSN++ + ++ + I+P +NQ E + + L C G+
Sbjct: 104 DYFDLFLVRDIGVSNYSVALLVDTLNYARIKPSVNQCEAHVYFARPQLRDVCREFGV 160
>UniRef50_Q9A2X8 Cluster: Oxidoreductase, aldo/keto reductase
family; n=3; Caulobacter|Rep: Oxidoreductase, aldo/keto
reductase family - Caulobacter crescentus (Caulobacter
vibrioides)
Length = 279
Score = 111 bits (266), Expect = 2e-23
Identities = 67/189 (35%), Positives = 105/189 (55%)
Frame = +2
Query: 140 ALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTR 319
ALG G + ++ V +A +E GYRHIDTA +Y +E VG AI N V R
Sbjct: 17 ALGFGTWQLENGTAVPLVEKA----LEIGYRHIDTAQIYGNERDVGA----AIRNSGVKR 68
Query: 320 EELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLET 499
+E+F+TTK+W D+ A + + ++SL+KLG+D +DL L+H+P KP+ + ET
Sbjct: 69 DEIFLTTKVWIDQFADGDLQRSAEKSLEKLGVDQVDLLLLHWP---KPE-----VPLAET 120
Query: 500 WQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEPLXAHCXSL 679
+ + R G R+IG+SNF + Q+ S +Q+E +P + + L A L
Sbjct: 121 LKALNAVRAKGWTRAIGLSNFPSAQLEEAAKLSEAPIATDQVEYHPYLSLKTLKAKADQL 180
Query: 680 GIAVMAYSP 706
G+++ A+SP
Sbjct: 181 GVSITAWSP 189
>UniRef50_Q18483 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 287
Score = 111 bits (266), Expect = 2e-23
Identities = 61/176 (34%), Positives = 100/176 (56%), Gaps = 2/176 (1%)
Frame = +2
Query: 191 VRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAI-ANGLVTREELFVTTKLWNDKHAR 367
+RQ + + GYR IDTA VY +E ++G+ + + + ANGL RE++++T+KL
Sbjct: 27 LRQVIDAGFKEGYRFIDTAQVYNNEAKIGRILEKLLPANGL-KREDIWITSKLAPSNAGV 85
Query: 368 DQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDY-LETWQGMQDARQLGLARS 544
+ +++ESL L ++Y+DL LIH+P ++ ++P N +E+W M + G RS
Sbjct: 86 KKARESIEESLSNLKVEYLDLLLIHWPGSSLKSENPANKKLRVESWNVMCEMMAEGKLRS 145
Query: 545 IGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+GVSNF + L +S + P +NQ+E +P Q+ L +C I AYS G
Sbjct: 146 VGVSNFEICHLEELKKDSNVVPAVNQVEYHPHFHQDDLVKYCNENNIHFQAYSSLG 201
>UniRef50_A5DRJ6 Cluster: Putative uncharacterized protein; n=4;
Pichia guilliermondii|Rep: Putative uncharacterized
protein - Pichia guilliermondii (Yeast) (Candida
guilliermondii)
Length = 287
Score = 111 bits (266), Expect = 2e-23
Identities = 73/206 (35%), Positives = 109/206 (52%), Gaps = 4/206 (1%)
Frame = +2
Query: 101 CIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQ 280
C L G +P A G G S + V +A ++ GYR IDTA Y++E + G+
Sbjct: 9 CFPLLNGSRIP--ACGVGVYLLPASQTAGIVEKA----LDVGYRLIDTAQEYENERETGE 62
Query: 281 GIAEAIANGLVT-REELFVTTKLWNDKHARDQVVPALQESLKKLG-LDYIDLYLIHFPIA 454
GI + RE++ TTK+ N D+ +L+ESL K+ L+YIDL LIH P++
Sbjct: 63 GIKAWLGKDKNNKREDVLYTTKITNLNQGYDRTWRSLKESLNKVKHLEYIDLVLIHDPLS 122
Query: 455 TKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLV--SNSYIRPVINQIE 628
K +ETW+ +Q+A G+ +SIGVSNF I L +P++NQIE
Sbjct: 123 DKKTR-------IETWKALQEAVDSGMVKSIGVSNFGKHHIQELYDWEGLKYKPIVNQIE 175
Query: 629 VNPTNTQEPLXAHCXSLGIAVMAYSP 706
++P ++ L +C +LGI + AY P
Sbjct: 176 LSPWLMRKDLVDYCQNLGIVLEAYCP 201
>UniRef50_P91997 Cluster: Putative uncharacterized protein; n=4;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 297
Score = 110 bits (265), Expect = 3e-23
Identities = 63/202 (31%), Positives = 113/202 (55%), Gaps = 3/202 (1%)
Frame = +2
Query: 107 QLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGI 286
+L++G +P V GT + T + V A+ A+ AGYR DTA Y +E+++G+ +
Sbjct: 14 KLNSGYNIPFVGFGTYKVTGEN------VPPAIDAALTAGYRMFDTAKYYLNEKELGEAL 67
Query: 287 AEAIANGLVTREELFVTTKLWND-KHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 463
+ ++R ++F+T+K + + K+ R+ ++ESL+ L DYID+YL+H+P
Sbjct: 68 KILLPKHGLSRSDVFLTSKFFPESKNCREACRGFVEESLQSLQTDYIDMYLVHYPKPNDS 127
Query: 464 D-DSPDNIDYLE-TWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNP 637
D D +N +Y + ++ +++A+ G RSIGVSN+ + L + + + P NQ+E +P
Sbjct: 128 DNDDVNNAEYRKIAYEVLEEAKAAGKVRSIGVSNYEIVHLEELKTYAKVPPCANQLEYHP 187
Query: 638 TNTQEPLXAHCXSLGIAVMAYS 703
+ PL +C I A+S
Sbjct: 188 HFARIPLQKYCKEKNIFFQAFS 209
>UniRef50_Q96JD6 Cluster: Aldo-keto reductase family 1 member C-like
protein 2; n=37; Euteleostomi|Rep: Aldo-keto reductase
family 1 member C-like protein 2 - Homo sapiens (Human)
Length = 320
Score = 110 bits (265), Expect = 3e-23
Identities = 79/217 (36%), Positives = 110/217 (50%), Gaps = 32/217 (14%)
Frame = +2
Query: 158 GTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVT 337
G + S V +AV AI+AGYRH D A Y +E +VG GI I G V RE+LF+
Sbjct: 8 GLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDLFIA 67
Query: 338 TKLWNDKHARDQVVPALQ---ESLKKLGLDY----------------------IDLYLIH 442
TKLW H + V A + ++LK LD + L H
Sbjct: 68 TKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELSFCLSH 127
Query: 443 FPIATKP-DDS----PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR 607
+ P D+S P + D+L+TW+ M+D GL ++IGVSNFN Q+ RL++ +R
Sbjct: 128 PRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLR 187
Query: 608 --PVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
P+ NQIE +P TQ+ L + C S ++V AY P G
Sbjct: 188 FKPLTNQIECHPYLTQKNLISFCQSRDVSVTAYRPLG 224
>UniRef50_A7SGW6 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 264
Score = 110 bits (264), Expect = 4e-23
Identities = 62/166 (37%), Positives = 94/166 (56%)
Frame = +2
Query: 209 WAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPAL 388
+A++ GYR +DTA +YQ+E++VG + ++ GL RE+++VTTKL + +
Sbjct: 41 FALKNGYRMLDTADIYQNEKEVGSAVRKS---GL-KREDIYVTTKLKPSEEGHSNALKYA 96
Query: 389 QESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNA 568
+ES+KKL + Y+DL+LIH P P NI + + + ++ GL RS+GVSNF
Sbjct: 97 KESIKKLDIGYVDLFLIHTP-------RPGNI--IAAYDALLTLKEEGLIRSVGVSNFGV 147
Query: 569 TQITRLVSNSYIRPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSP 706
+ L P INQIE+NP QE + +C GI V Y+P
Sbjct: 148 HHLEELRKAGCRTPAINQIEINPFWRQEEIIKYCNKHGITVEGYAP 193
>UniRef50_O14088 Cluster: Xylose and arabinose reductase; n=1;
Schizosaccharomyces pombe|Rep: Xylose and arabinose
reductase - Schizosaccharomyces pombe (Fission yeast)
Length = 275
Score = 110 bits (264), Expect = 4e-23
Identities = 61/170 (35%), Positives = 98/170 (57%), Gaps = 1/170 (0%)
Frame = +2
Query: 200 AVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVV 379
+VY A++ GYRHID+A +Y +E G+ I + + RE+++ T+KL ND +
Sbjct: 32 SVYAALQCGYRHIDSAQMYHNEADCGRAILKFMEETGTKREDIWFTSKL-NDLSGYKSTL 90
Query: 380 PALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSN 559
++ S+K GL YIDL+L+H P D +E+W+ ++ + G R+IGVSN
Sbjct: 91 SSIDASVKACGLGYIDLFLLHSPYG----------DRIESWKALEKGVEEGKLRAIGVSN 140
Query: 560 FNATQITRLV-SNSYIRPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSP 706
F I L+ S+ I P +NQIE++P +Q+ + +C S GI + AY+P
Sbjct: 141 FGPHHIQELLDSHPKIIPCVNQIELHPFCSQQKVVDYCESKGIQLAAYAP 190
>UniRef50_UPI0000519CC2 Cluster: PREDICTED: similar to CG2767-PA;
n=1; Apis mellifera|Rep: PREDICTED: similar to CG2767-PA
- Apis mellifera
Length = 321
Score = 109 bits (263), Expect = 5e-23
Identities = 70/216 (32%), Positives = 114/216 (52%), Gaps = 13/216 (6%)
Frame = +2
Query: 104 IQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 283
I L G +P + GT + K + A+ A+EAGYRHIDTA Y++E+ +G
Sbjct: 6 ILLPNGELMPIIGFGTWQAQEKE------LEDALNIALEAGYRHIDTATSYENEKVIGDV 59
Query: 284 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK- 460
+ + + R ++F+ TKL + + V ++ SL+ L L+Y+DLYLIH PI +
Sbjct: 60 LKNWFDSKKLKRSDIFIVTKLPAVGNRAEDVEKWIKTSLQNLRLEYLDLYLIHVPIGFEK 119
Query: 461 ------PDDSPDNI------DYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI 604
P D +I +++E W M+ + G ++IG+SNFN +QI R++ N+ +
Sbjct: 120 VGDILHPFDENGHIRLDNSTNHVEIWAEMEKQVKCGRTKAIGLSNFNISQIKRILKNTKM 179
Query: 605 RPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+ + QIE++ Q+ L C I + AYSP G
Sbjct: 180 KISMLQIELHVYFQQKELVKFCKQENIPITAYSPLG 215
>UniRef50_Q3E9M9 Cluster: Uncharacterized protein At5g01670.2; n=7;
Magnoliophyta|Rep: Uncharacterized protein At5g01670.2 -
Arabidopsis thaliana (Mouse-ear cress)
Length = 349
Score = 109 bits (263), Expect = 5e-23
Identities = 77/235 (32%), Positives = 126/235 (53%), Gaps = 33/235 (14%)
Frame = +2
Query: 107 QLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGI 286
+L +G +P V LGT R ++ + ++ +E GYRHIDTA Y D+ +VGQGI
Sbjct: 17 RLLSGHKIPAVGLGTWRSGSQAAHAVVTA------IVEGGYRHIDTAWEYGDQREVGQGI 70
Query: 287 AEAIANGL---------------VTREELFVTTKLWN-----------DKHARDQVVPAL 388
A+ GL + R+ + +++ L N + + ++V PAL
Sbjct: 71 KRAMHAGLERRDLFVTSKLWYTLILRKMINLSSPLMNVLVGTCLNKRCTELSPERVRPAL 130
Query: 389 QESLKKLGLDYIDLYLIHFPI-----ATKPDDSPDNIDY-LE-TWQGMQDARQLGLARSI 547
Q +LK+L L+Y+DLYLIH+PI A+KP + D +D+ +E W+ M++ + L R+I
Sbjct: 131 QNTLKELQLEYLDLYLIHWPIRLREGASKPPKAGDVLDFDMEGVWREMENLSKDSLVRNI 190
Query: 548 GVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
GV NF T++ +L+ + + P + Q+E++P + + C I V AYSP G
Sbjct: 191 GVCNFTVTKLNKLLGFAELIPAVCQMEMHPGWRNDRILEFCKKNEIHVTAYSPLG 245
>UniRef50_Q5T2L2 Cluster: Aldo-keto reductase family 1 member C-like
protein 1; n=14; Eutheria|Rep: Aldo-keto reductase
family 1 member C-like protein 1 - Homo sapiens (Human)
Length = 302
Score = 109 bits (263), Expect = 5e-23
Identities = 73/208 (35%), Positives = 107/208 (51%), Gaps = 1/208 (0%)
Frame = +2
Query: 92 QAPCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQ 271
Q+ ++L+ G +P + GT A +A AI+ G+RHID+A +YQ+EE+
Sbjct: 7 QSHSVRLNDGPFMPVLGFGT---YAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEE 63
Query: 272 VGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPI 451
VGQ I E IA+G V REE+F T KLW + V PAL+ SLKKLG DY+DL++IH P
Sbjct: 64 VGQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPF 123
Query: 452 ATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQ-IE 628
A K + L +DA + ++ + + ++ +P NQ +E
Sbjct: 124 AMKQPGK----ELLP-----KDASGEIILETVELCDTWELELILNKPGLRYKPTCNQVVE 174
Query: 629 VNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+P Q L C S I ++AYS G
Sbjct: 175 CHPYLNQSKLLEFCKSKDIVLVAYSALG 202
>UniRef50_Q5NLW3 Cluster: Putative oxidoreductase; n=1; Zymomonas
mobilis|Rep: Putative oxidoreductase - Zymomonas mobilis
Length = 273
Score = 109 bits (262), Expect = 7e-23
Identities = 67/203 (33%), Positives = 105/203 (51%)
Frame = +2
Query: 104 IQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 283
+ L+ G +P + G + ++S+ + + GYR +DTAA Y++EE VG+G
Sbjct: 7 VVLNDGHSMPAIGQGVYQLNPAQAESMVAL------GYDLGYRAVDTAAWYENEEGVGEG 60
Query: 284 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 463
+ A F+TTKL R AL +S++ LG+ ++LYLIH+P
Sbjct: 61 LRSRHARS-------FITTKLMPQDMGRVNCFVALDKSIRNLGVTSLNLYLIHWP----- 108
Query: 464 DDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTN 643
D Y ETWQ + R +G A SIGVSNF + ++++S + P +NQIE++P
Sbjct: 109 --GQDRKRYEETWQTLIQIRAIGKASSIGVSNFTIDHLDHIIADSGVVPAVNQIELHPYF 166
Query: 644 TQEPLXAHCXSLGIAVMAYSPFG 712
Q+ L A+ GI ++SP G
Sbjct: 167 QQKELRAYHAERGIVTTSWSPLG 189
>UniRef50_Q3CZS2 Cluster: Oxidoreductase, aldo/keto reductase
family; n=2; Streptococcus agalactiae|Rep:
Oxidoreductase, aldo/keto reductase family -
Streptococcus agalactiae H36B
Length = 245
Score = 109 bits (262), Expect = 7e-23
Identities = 67/186 (36%), Positives = 103/186 (55%)
Frame = +2
Query: 152 GRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELF 331
G G + D + Q+V A++ GYR IDTA+ Y +EE VG+ AI + R+E+F
Sbjct: 19 GFGVFQIDDPLE-CEQSVLDALQVGYRLIDTASGYLNEEAVGR----AIKKSGIPRKEIF 73
Query: 332 VTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGM 511
V TKLW + ++ PA+ +LK+L LDYI+LYLIH P+ DY + +
Sbjct: 74 VVTKLWIQDASEEKAGPAIDRALKRLQLDYINLYLIHQPMG----------DYYGACRAL 123
Query: 512 QDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEPLXAHCXSLGIAV 691
+ A + A +IGVSNF+ ++ L+ ++ I P +NQI++NP + + GI
Sbjct: 124 EKAYEERKALAIGVSNFSNGRVQDLILHNKIIPAVNQIQMNPFHPAKDQVEWLSKKGIHT 183
Query: 692 MAYSPF 709
MA+ PF
Sbjct: 184 MAWGPF 189
>UniRef50_Q11DV1 Cluster: Aldo/keto reductase; n=10;
Alphaproteobacteria|Rep: Aldo/keto reductase -
Mesorhizobium sp. (strain BNC1)
Length = 274
Score = 109 bits (261), Expect = 9e-23
Identities = 67/183 (36%), Positives = 102/183 (55%)
Frame = +2
Query: 152 GRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELF 331
G G + SD+ V + + A+EAG+RH DTA +YQ+E +G+ + A A RE+LF
Sbjct: 15 GFGVFRMSDA--EVERIIPAALEAGFRHFDTAQIYQNEAALGRALERAGAR----REDLF 68
Query: 332 VTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGM 511
+TTK+W D ++ D+ ++ ESL+KL +D +DL L+H+P P + +E +
Sbjct: 69 LTTKVWVDNYSADKFAASVDESLEKLKVDQVDLLLLHWPAHEVPVAA-----QIERLNAV 123
Query: 512 QDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEPLXAHCXSLGIAV 691
+DA G R IGVSN N Q+ ++ S V NQ+E++P Q L A +AV
Sbjct: 124 KDA---GKTRFIGVSNQNIAQMRESIARSAAPIVTNQVELHPYLPQHSLVAAARDSAVAV 180
Query: 692 MAY 700
AY
Sbjct: 181 TAY 183
>UniRef50_Q9P734 Cluster: Related to 2, 5-diketo-D-gluconic acid
reductase; n=5; Pezizomycotina|Rep: Related to 2,
5-diketo-D-gluconic acid reductase - Neurospora crassa
Length = 289
Score = 109 bits (261), Expect = 9e-23
Identities = 62/176 (35%), Positives = 101/176 (57%), Gaps = 6/176 (3%)
Frame = +2
Query: 197 QAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIAN-----GLVTREELFVTTKLWNDKH 361
+AV WA+ AGYR D+A Y +E + GQ I +++ GL TR+++ T+KL ++
Sbjct: 38 RAVRWALGAGYRGFDSAQWYYNEREAGQAILSFLSSPENTAGL-TRKDVHFTSKLRDNST 96
Query: 362 ARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLAR 541
D V ++ +S+K GL YIDL+L+H P+ + L +W+ ++DA G +
Sbjct: 97 NYDAVRASISKSVKASGLGYIDLFLLHSPLGGREAR-------LTSWKAVEDAVLAGEVK 149
Query: 542 SIGVSNFNATQITRLVSNSY-IRPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSP 706
GVSN+ + ++S + I+P++NQIE +P NTQ + A C GI + AY+P
Sbjct: 150 MAGVSNYGVKHLDEVMSAPFKIKPLVNQIECHPFNTQPEIRAACEKYGIVIEAYAP 205
>UniRef50_Q5XJM7 Cluster: Zgc:101765; n=5; Eumetazoa|Rep: Zgc:101765
- Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 288
Score = 108 bits (259), Expect = 2e-22
Identities = 67/209 (32%), Positives = 109/209 (52%), Gaps = 4/209 (1%)
Frame = +2
Query: 98 PCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 277
P + L+ +P + LGT R + AV A++AGYR DTAAVY++E +G
Sbjct: 6 PSVLLNNDIQMPLLGLGTFRLQGQED-----TYSAVDAALKAGYRAFDTAAVYRNEAHLG 60
Query: 278 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFP--- 448
+ + ++RE++F+T+KL K + Q+SL++LGL YIDLYLIH+P
Sbjct: 61 HALRCLLPKHGLSREDVFITSKL-GPKDQGSKARNGCQKSLEQLGLGYIDLYLIHWPGTQ 119
Query: 449 -IATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQI 625
+ +P+N ++W+ +++ G R+IGVSN+ + L+ + + P + Q+
Sbjct: 120 GLPVGDKRNPEN--RAQSWRVLEEFYSEGKFRAIGVSNYTVEHMQELLKSCKVPPAVLQV 177
Query: 626 EVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
E +P Q L C G+ AYS G
Sbjct: 178 EFHPKLLQNDLRGLCKIRGVCFQAYSSLG 206
>UniRef50_A0L1A2 Cluster: Aldo/keto reductase; n=8;
Gammaproteobacteria|Rep: Aldo/keto reductase -
Shewanella sp. (strain ANA-3)
Length = 280
Score = 108 bits (259), Expect = 2e-22
Identities = 65/189 (34%), Positives = 100/189 (52%), Gaps = 1/189 (0%)
Frame = +2
Query: 152 GRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELF 331
G GT + D+ AV A+E G RHIDTA +Y +E+ VG +AI + REELF
Sbjct: 21 GTGTFRLKDNAAF--DAVLMALEEGSRHIDTAQIYGNEQAVG----DAINTSGIPREELF 74
Query: 332 VTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGM 511
+TTK+W + +++ ++ +SL L Y+DL LIH+P+ + D P ++YL + +
Sbjct: 75 ITTKVWTENLTKERFETSVIDSLTALQTKYLDLLLIHWPLNS---DEPSMVEYLSELKAV 131
Query: 512 QDARQLGLARSIGVSNFNATQITRLVSNSYIRPV-INQIEVNPTNTQEPLXAHCXSLGIA 688
D GL R IGVSNF Q+ + ++ + NQ+EV+P + C +
Sbjct: 132 LDK---GLTRRIGVSNFTNAQLAQAIAILGEGVIYTNQVEVHPYLINRKVTDFCRQHNVL 188
Query: 689 VMAYSPFGF 715
V Y PF +
Sbjct: 189 VTGYMPFAY 197
>UniRef50_Q68A33 Cluster: Aldo-keto reductase 1a; n=1; Ciona
intestinalis|Rep: Aldo-keto reductase 1a - Ciona
intestinalis (Transparent sea squirt)
Length = 584
Score = 108 bits (259), Expect = 2e-22
Identities = 75/222 (33%), Positives = 117/222 (52%), Gaps = 14/222 (6%)
Frame = +2
Query: 92 QAPCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQ 271
+ P ++L++G +P + LGT R +K +++ A++ GYR +DTA +Y E++
Sbjct: 256 EIPDVKLNSGYMMPPIGLGTARLFSKTYETVKT-------ALKLGYRMLDTAQIYTGEDK 308
Query: 272 VG-------QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDL 430
+ + I AIA+ V R ELF+ TKL + ++ + ++ESLKKL DYIDL
Sbjct: 309 INNFKVSSEEEIGRAIADSDVPRSELFIVTKLAPESMEKENAIAKVEESLKKLRTDYIDL 368
Query: 431 YLIH-FPIATK--PDDS--PD--NIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLV 589
LIH F ++T PDD+ P+ N +L W+ M++ + GL RSIGVSN + LV
Sbjct: 369 LLIHDFYMSTACGPDDTDLPECKNNPFL-AWKTMEEMQAKGLVRSIGVSNIYIEDLQYLV 427
Query: 590 SNSYIRPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFGF 715
+ Q +P + + + A C I M YS GF
Sbjct: 428 KMAKTPISAVQNWFDPLHQEREIRALCAKNNIRFMGYSALGF 469
>UniRef50_A2QB88 Cluster: Contig An01c0460, complete genome.
precursor; n=1; Aspergillus niger|Rep: Contig An01c0460,
complete genome. precursor - Aspergillus niger
Length = 351
Score = 108 bits (259), Expect = 2e-22
Identities = 78/215 (36%), Positives = 107/215 (49%), Gaps = 21/215 (9%)
Frame = +2
Query: 131 PXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGL 310
P V LGT +G A V++AV A+ GYRHIDTA Y +E +VG EAI
Sbjct: 47 PAVGLGTFQGDAGNRG----VKEAVLQALRCGYRHIDTATAYGNEIEVG----EAIKESR 98
Query: 311 VTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDY-IDLYLIHFPIATKP---DDSPD 478
+ REE+ VTTKL H V AL SL++L L+Y + ++L + P PD
Sbjct: 99 IPREEIIVTTKLAQTWHRVSDVERALDLSLERLQLNYGLSMHLYSASSYSVPHAYSPGPD 158
Query: 479 N-----------------IDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR 607
N DY TW M+ G + IGVSNFN ++ RL+ ++ I
Sbjct: 159 NNTIRHPNGKPIIDHELSRDYPSTWAAMESLVDKGKLKMIGVSNFNILKLERLLGSARIP 218
Query: 608 PVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
P +NQIE++P Q L C + GI ++A+ P G
Sbjct: 219 PAVNQIELHPYLPQVELVRFCKANGIHLVAHQPLG 253
>UniRef50_Q76L37 Cluster: Conjugated polyketone reductase C1; n=3;
Saccharomycetales|Rep: Conjugated polyketone reductase
C1 - Candida parapsilosis (Yeast)
Length = 304
Score = 107 bits (258), Expect = 2e-22
Identities = 73/222 (32%), Positives = 119/222 (53%), Gaps = 12/222 (5%)
Frame = +2
Query: 83 MAVQAPCIQLHAGXPLPXVALGTGRGTAKX--SDSIXXVRQAVYWAIEAGYRHIDTAAVY 256
M++ +L G +P VA GTG K +D + + A+ +G+RHID A +Y
Sbjct: 1 MSLAGKEFKLSNGNKIPAVAFGTGTKYFKRGHNDLDKQLIGTLELALRSGFRHIDGAEIY 60
Query: 257 QDEEQVGQGIAEAIANGLVTREELFVTTKL------WNDKHARDQ-VVPALQESLKKLGL 415
+++G A+ N + R+++F+T K ++ KH++ Q AL+ L+ LGL
Sbjct: 61 GTNKEIGI----ALKNVGLNRKDVFITDKYNSGNHTYDGKHSKHQNPYNALKADLEDLGL 116
Query: 416 DYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLV-S 592
+Y+DLYLIHFP + + D +E W+ ++ A+ GLAR+IGVSNF + ++ +
Sbjct: 117 EYVDLYLIHFPYIS---EKSHGFDLVEAWRYLERAKNEGLARNIGVSNFTIENLKSILDA 173
Query: 593 NSYIRPVINQIEVNP-TNTQEP-LXAHCXSLGIAVMAYSPFG 712
N+ PV+NQIE + Q P + + GI + AY P G
Sbjct: 174 NTDSIPVVNQIEFSAYLQDQTPGIVEYSQQQGILIEAYGPLG 215
>UniRef50_Q2CAL9 Cluster: 2,5-didehydrogluconate reductase; n=2;
Oceanicola granulosus HTCC2516|Rep:
2,5-didehydrogluconate reductase - Oceanicola granulosus
HTCC2516
Length = 275
Score = 107 bits (257), Expect = 3e-22
Identities = 74/195 (37%), Positives = 99/195 (50%), Gaps = 3/195 (1%)
Frame = +2
Query: 131 PXVALGTGRGT--AKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIAN 304
P + G G GT + D I A+ A+E GYRH+DTA Y E +VG+ I A
Sbjct: 9 PEIMPGLGFGTYGRQGEDGIS----AILCALETGYRHLDTAQDYDTEAEVGEAIRRA--- 61
Query: 305 GLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNI 484
GL RE LFVTTK+ +VP++ SL+ +GLD DL LIH+P P+
Sbjct: 62 GL-PREALFVTTKVRPANFGPGDLVPSVARSLETMGLDRADLVLIHWP---APNGERPLS 117
Query: 485 DYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVI-NQIEVNPTNTQEPLX 661
DY+ + +AR GL R +GVSNF +T + P++ NQ+E+NP L
Sbjct: 118 DYIPQ---LAEARAQGLTRHVGVSNFPVALLTEARALLGDVPILTNQVELNPWFRNRTLA 174
Query: 662 AHCXSLGIAVMAYSP 706
HC GI V Y P
Sbjct: 175 DHCMGAGIRVTCYQP 189
>UniRef50_A2QL02 Cluster: Putative frameshift; n=1; Aspergillus
niger|Rep: Putative frameshift - Aspergillus niger
Length = 357
Score = 107 bits (257), Expect = 3e-22
Identities = 77/213 (36%), Positives = 116/213 (54%), Gaps = 12/213 (5%)
Frame = +2
Query: 110 LHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 289
L+ G +P ALG G T + DS + V ++ G R IDTA VY E+QVG+GI
Sbjct: 40 LNTGAKIP--ALGVG--TFQDPDS---QEETVCQVLQRGMRLIDTARVYGVEQQVGRGIK 92
Query: 290 EAIANGLVTREELFVTTKLW-NDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK-- 460
++ G V REE+F+ TKLW ND H D V A+ +SL+ L Y+DL L+H+P K
Sbjct: 93 KS---G-VPREEIFLGTKLWCNDFHP-DDVERAVDDSLRDLYTPYVDLLLMHYPCTFKRG 147
Query: 461 ----PDDSPDNI-----DYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPV 613
P D+ + +++TW+ ++ + G R+IGVSNF+ +I L+ + P
Sbjct: 148 EDRFPRDAEGRMIHGETTFVDTWRALEKVVKTGKVRAIGVSNFSKGEIETLLRETSTVPA 207
Query: 614 INQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
++Q+EV+P Q+ GI V+ +SP G
Sbjct: 208 VHQMEVHPYLQQKGFNEWLREKGIHVVQFSPLG 240
>UniRef50_A4YQ04 Cluster: 2,5-diketo-D-gluconate reductase B; n=15;
Proteobacteria|Rep: 2,5-diketo-D-gluconate reductase B -
Bradyrhizobium sp. (strain ORS278)
Length = 273
Score = 107 bits (256), Expect = 4e-22
Identities = 71/196 (36%), Positives = 101/196 (51%)
Frame = +2
Query: 119 GXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAI 298
G LP + LGT R R AV A+ GYRHIDTA +Y +E+ +G +A A
Sbjct: 8 GVRLPKLGLGTFRMQG------TVCRDAVESALALGYRHIDTAEMYANEDAIGAALAAA- 60
Query: 299 ANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPD 478
+ RE+L VTTK+W + A D + A SLKKL LD++DLYLIH+P AT
Sbjct: 61 ---QIAREDLHVTTKVWPENLAPDAIRRAFDTSLKKLRLDFVDLYLIHWP-AT------- 109
Query: 479 NIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEPL 658
++ + + +Q G R+IGV+NF + + V + NQ+E + Q L
Sbjct: 110 GMNLPAAMETLMALKQEGRTRAIGVANFTVALLKQAVEDIQAPVACNQVEYHVMLDQSKL 169
Query: 659 XAHCXSLGIAVMAYSP 706
A+ S I ++AY P
Sbjct: 170 MAYMKSRSIPLVAYCP 185
>UniRef50_Q5UX52 Cluster: Oxidoreductase aldo/keto reductase family;
n=1; Haloarcula marismortui|Rep: Oxidoreductase
aldo/keto reductase family - Haloarcula marismortui
(Halobacterium marismortui)
Length = 274
Score = 107 bits (256), Expect = 4e-22
Identities = 72/196 (36%), Positives = 100/196 (51%)
Frame = +2
Query: 119 GXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAI 298
G +P + LGT + T + R+ V A+ GYRHIDTA Y +E QVG G+ A
Sbjct: 8 GTSVPALGLGTWQLTGQSC------RETVETALGMGYRHIDTAQAYGNERQVGLGMDAAA 61
Query: 299 ANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPD 478
V RE++F+TTKL V + +ESL KLG DY+DL LIH+P ++P
Sbjct: 62 ----VDREDVFLTTKLDGSNRDERSVRRSTRESLNKLGTDYLDLLLIHWP------NTPW 111
Query: 479 NIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEPL 658
ET M D + GL R IGVSNF+ + + R S +Q++ +P Q L
Sbjct: 112 MASLSETLGAMNDVVEEGLVRHIGVSNFSPSLLDRARDISSAPIFTDQVQYHPYWDQRKL 171
Query: 659 XAHCXSLGIAVMAYSP 706
+C + + AYSP
Sbjct: 172 LDYCRIHDVLLTAYSP 187
>UniRef50_Q0CLQ2 Cluster: Putative uncharacterized protein; n=1;
Aspergillus terreus NIH2624|Rep: Putative
uncharacterized protein - Aspergillus terreus (strain
NIH 2624)
Length = 301
Score = 106 bits (254), Expect = 6e-22
Identities = 83/237 (35%), Positives = 115/237 (48%), Gaps = 35/237 (14%)
Frame = +2
Query: 107 QLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGI 286
+L +G +P V LGT +K + V AV A+ GYRHID AA Y +E +VG G
Sbjct: 8 KLSSGYDMPAVGLGTW--LSKPHE----VENAVETALRLGYRHIDAAACYLNENEVGNGW 61
Query: 287 AEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYL---------- 436
++ G V R+++F+T+KLWN H D V A+ ++LK L DY+DLYL
Sbjct: 62 KKS---G-VPRDQIFITSKLWNTHHHPDHVEEAVNKTLKDLQTDYLDLYLVFPSLLVLIH 117
Query: 437 ----------IHFPIATK-------PDDSPD------NIDYLETWQGMQDARQLGLARSI 547
IH+P+A + P D NI +TW ++ G RSI
Sbjct: 118 DLLSLLTNNKIHWPVAFEHTNETLTPIDPVSKRFRLANIPIADTWAALEKLVDAGKVRSI 177
Query: 548 GVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEPLXAHCXS--LGIAVMAYSPFG 712
GVSNF +I L+ + I P +NQIE +P Q L + I +AYSP G
Sbjct: 178 GVSNFTIEKIEELLKTARIPPAVNQIEAHPYLQQPALHKYLKEKVTNILSVAYSPLG 234
>UniRef50_Q8EUH6 Cluster: Oxidoreductase; n=1; Mycoplasma
penetrans|Rep: Oxidoreductase - Mycoplasma penetrans
Length = 285
Score = 105 bits (253), Expect = 9e-22
Identities = 65/207 (31%), Positives = 110/207 (53%)
Frame = +2
Query: 104 IQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 283
I+L G +P + LG + + ++ + +A+ + GYR IDTA VY +EE VG
Sbjct: 4 IKLANGLHMPIIGLGVYKAEGENCEN--TIIKAID---DYGYRMIDTAQVYFNEEFVGNA 58
Query: 284 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 463
I + + RE++F+TTK+W + + + ++ +SLKKL +YIDL L+H P
Sbjct: 59 IKQT----KIKREDIFITTKVWISNYGYNNTMYSISKSLKKLQTNYIDLVLLHQPFG--- 111
Query: 464 DDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTN 643
DY W+ ++ + G+ ++IGVSNF A ++ + ++PVINQIE++P
Sbjct: 112 -------DYYSAWKALEVLYKKGIVKAIGVSNFEADRLVDFCLHVDVKPVINQIELHPLR 164
Query: 644 TQEPLXAHCXSLGIAVMAYSPFGFVVS 724
+ G+AV +++ FG S
Sbjct: 165 QRIEDLHWNNKYGVAVESWASFGRATS 191
>UniRef50_Q09632 Cluster: Probable oxidoreductase ZK1290.5; n=2;
Caenorhabditis|Rep: Probable oxidoreductase ZK1290.5 -
Caenorhabditis elegans
Length = 321
Score = 105 bits (252), Expect = 1e-21
Identities = 72/204 (35%), Positives = 104/204 (50%), Gaps = 1/204 (0%)
Frame = +2
Query: 98 PCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 277
P L +P + LGT D++ ++ + GYR IDTA Y E+Q+G
Sbjct: 3 PTTVLSNNVEMPLIGLGTTHSGGYYHDAV------LHSIKKCGYRLIDTAKRYGVEKQLG 56
Query: 278 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 457
A+ N V REE+F++TKLW D+V A Q S +KL DY+D+Y+IH P
Sbjct: 57 I----AVKNCSVPREEMFLSTKLW-PVDCGDEVYNAFQTSCEKLQTDYLDMYMIHMP--Q 109
Query: 458 KPDDSPDNIDYLE-TWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVN 634
PD + + E TW+ M+ + RSIGVSN++ + L+ + I P NQ+E++
Sbjct: 110 LPDWIVNQKETKEKTWRQMELLYEDEHVRSIGVSNYSIEDLDELLEFASILPHANQVELH 169
Query: 635 PTNTQEPLXAHCXSLGIAVMAYSP 706
P Q L +C LGI M Y P
Sbjct: 170 PWFHQADLKNYCDELGILTMGYCP 193
>UniRef50_P70883 Cluster: AkrI; n=1; Butyrivibrio fibrisolvens|Rep:
AkrI - Butyrivibrio fibrisolvens
Length = 172
Score = 105 bits (251), Expect = 1e-21
Identities = 54/153 (35%), Positives = 90/153 (58%)
Frame = +2
Query: 104 IQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 283
I+L+ G +P G GT K D +V A++ GYRHIDTAA Y++E+ V
Sbjct: 8 IKLNNGTAIPMF----GYGTYKIKDQ-NEAYNSVRLALKNGYRHIDTAAFYENEKFVANA 62
Query: 284 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 463
I + + RE++FVT+K W + D+ + A ++++ ++ +DY+DLYL+H+P +
Sbjct: 63 IKDFMEESQTKREDIFVTSKAWKTELGYDKTLAAFEKTMNEMQMDYLDLYLVHWPASYAF 122
Query: 464 DDSPDNIDYLETWQGMQDARQLGLARSIGVSNF 562
DD +N + +TW+ M + + G ++IGVSNF
Sbjct: 123 DDDWENTN-RQTWKAMTEIYKSGRVKAIGVSNF 154
>UniRef50_A3T261 Cluster: Putative uncharacterized protein; n=1;
Sulfitobacter sp. NAS-14.1|Rep: Putative uncharacterized
protein - Sulfitobacter sp. NAS-14.1
Length = 274
Score = 105 bits (251), Expect = 1e-21
Identities = 65/172 (37%), Positives = 88/172 (51%)
Frame = +2
Query: 191 VRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARD 370
V V A+ G+RHIDTA YQ+EEQVG+G+ A V R+E+F+TTK+ + + +
Sbjct: 26 VADMVAAALSEGFRHIDTAQAYQNEEQVGEGLRRAD----VRRDEVFLTTKILPEHFSPE 81
Query: 371 QVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIG 550
A SLK+LG DY+DL L+H+P P ET + D G R G
Sbjct: 82 AFTAAADASLKRLGTDYVDLLLLHWPSKEVP--------IAETIGALNDLISAGKVRHGG 133
Query: 551 VSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSP 706
VSNF + + + NQIE++P Q + AH S GI AYSP
Sbjct: 134 VSNFTMDMVDQAQAALNTPLAANQIELHPLIDQTRMIAHLASKGIPAEAYSP 185
>UniRef50_Q6CEJ0 Cluster: Yarrowia lipolytica chromosome B of strain
CLIB122 of Yarrowia lipolytica; n=1; Yarrowia
lipolytica|Rep: Yarrowia lipolytica chromosome B of
strain CLIB122 of Yarrowia lipolytica - Yarrowia
lipolytica (Candida lipolytica)
Length = 302
Score = 104 bits (250), Expect = 2e-21
Identities = 71/208 (34%), Positives = 109/208 (52%), Gaps = 5/208 (2%)
Frame = +2
Query: 98 PCIQLHAGXPLPXVALGTGRGTAK--XSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQ 271
P ++L G +P + G+G + + AV AI AG+ HIDTA Y E+Q
Sbjct: 4 PKVKLSNGLEIPAIGFGSGTKWKRPPGEKEERELIDAVVSAINAGHLHIDTAEFYGTEKQ 63
Query: 272 VGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPI 451
+G+ I E+ G V R+++F+T+K A D + ++ LK L DY DL+LIH P
Sbjct: 64 IGEAIKES---G-VPRKDIFLTSKTLFGLLA-DDPIESISNQLKTLQTDYFDLFLIHVP- 117
Query: 452 ATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEV 631
P+D N D + W ++ + GLA++IGVSN + ++ ++ + I+P +NQIE
Sbjct: 118 ---PNDDI-NYDLAKAWGVLEQLYEKGLAKAIGVSNHSPAELETIIKVAKIKPHVNQIEF 173
Query: 632 NPTNTQEP---LXAHCXSLGIAVMAYSP 706
+P QEP + C I V YSP
Sbjct: 174 HPL-LQEPTPGIVDFCKQHDIVVEGYSP 200
>UniRef50_A3WP89 Cluster: Aldo/keto reductase; n=1; Idiomarina
baltica OS145|Rep: Aldo/keto reductase - Idiomarina
baltica OS145
Length = 263
Score = 103 bits (248), Expect = 3e-21
Identities = 64/166 (38%), Positives = 92/166 (55%), Gaps = 1/166 (0%)
Frame = +2
Query: 212 AIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQ 391
AI+ GY HIDTA Y +E VG+ +A+ T +++FVTTK+W +K A V+ +LQ
Sbjct: 24 AIDMGYEHIDTAQFYGNEADVGKALAQH------TNKDVFVTTKVWYEKLAYQDVLDSLQ 77
Query: 392 ESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNAT 571
S KL D IDL LIH+P P+ D + ET +Q A+Q GL + +GVSNF
Sbjct: 78 VSRDKLQRDTIDLALIHWP---SPN---DEVPVEETLDALQKAQQDGLIKHLGVSNFTID 131
Query: 572 QITRLVSNSYIRPVI-NQIEVNPTNTQEPLXAHCXSLGIAVMAYSP 706
+ R ++ ++ NQIEV+P + C +G+ V AY P
Sbjct: 132 LLNRAAAHVGKDEILTNQIEVHPFFQNHAITDACKQMGVKVTAYLP 177
>UniRef50_Q17568 Cluster: Putative uncharacterized protein; n=1;
Caenorhabditis elegans|Rep: Putative uncharacterized
protein - Caenorhabditis elegans
Length = 287
Score = 103 bits (248), Expect = 3e-21
Identities = 64/206 (31%), Positives = 106/206 (51%), Gaps = 4/206 (1%)
Frame = +2
Query: 107 QLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGI 286
+L G +P +ALGT AK V +A ++ GYR DTA Y++E+ +G +
Sbjct: 3 KLKNGQEIPKLALGTYE--AKGDQLFAAVDEA----LKVGYRSFDTAKYYENEKDLGLAL 56
Query: 287 AEAIANGLVTREELFVTTKL--WNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 460
+ + E++++T+K+ ++ K+A + + + ESL+ L Y+DL L+H+P
Sbjct: 57 KTLLPRHNICSEDIYLTSKVFPYSSKNAAELIRKDVNESLELLDRKYLDLVLVHYPRPLD 116
Query: 461 PDDSPDNIDYL--ETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVN 634
+D +N +TW ++ G RSIGVSN+ I + S I P +NQIE +
Sbjct: 117 TEDLNENNKMYRKDTWIALEKLHAEGKIRSIGVSNYEPHHIEEMRSYITIEPQVNQIEYH 176
Query: 635 PTNTQEPLXAHCXSLGIAVMAYSPFG 712
P ++ L A+C I A+SP G
Sbjct: 177 PHFQRKVLRAYCNKNEILFQAFSPLG 202
>UniRef50_Q1Q8W8 Cluster: Aldo/keto reductase; n=1; Psychrobacter
cryohalolentis K5|Rep: Aldo/keto reductase -
Psychrobacter cryohalolentis (strain K5)
Length = 282
Score = 103 bits (247), Expect = 5e-21
Identities = 69/195 (35%), Positives = 106/195 (54%), Gaps = 2/195 (1%)
Frame = +2
Query: 128 LPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANG 307
+P + LGT + T + D I V Q + GY HIDTA Y +E +VG+GI ++ G
Sbjct: 16 IPVLGLGTWQSTGQ--DCIDVVSQG----LRMGYEHIDTAQAYGNEVEVGKGIKQS---G 66
Query: 308 LVTREELFVTTKLWND--KHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDN 481
V R++ F+TTK++ D K +++V A + SL+ L DY+DL L+H+P D
Sbjct: 67 -VARDKFFLTTKIFPDDMKFEPEKLVAAAKRSLENLDTDYVDLLLLHWP--------DDR 117
Query: 482 IDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEPLX 661
+ ET + + ++ GL R+IGVSNFN I + + V+NQ+E +P Q+ L
Sbjct: 118 VPLSETIPALCELQKQGLTRNIGVSNFNIANIIEAKRYADVPIVVNQVEFHPFIKQKTLQ 177
Query: 662 AHCXSLGIAVMAYSP 706
+ I + AYSP
Sbjct: 178 TFLNNHHILLEAYSP 192
>UniRef50_Q00XM4 Cluster: Aldo/keto reductase family proteins; n=2;
Ostreococcus|Rep: Aldo/keto reductase family proteins -
Ostreococcus tauri
Length = 336
Score = 103 bits (247), Expect = 5e-21
Identities = 64/203 (31%), Positives = 111/203 (54%), Gaps = 5/203 (2%)
Frame = +2
Query: 119 GXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAI 298
G +P +A GT R + R AV A+ G++H+DTA+VY +E VG+ +
Sbjct: 59 GITMPMLAFGTYRLRGETC------RDAVRDALRCGFQHVDTASVYGNERDVGEALRACH 112
Query: 299 ANGLVTREELFVTTKLW-NDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSP 475
E +FVT+K+ ++ + ++ A+ ++LG DL L+H+P K +SP
Sbjct: 113 RE---VSERIFVTSKIAPSEMRSEEEAAAAIAGVNERLGRTP-DLVLVHWPGRDK--ESP 166
Query: 476 DNIDYLE----TWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTN 643
D+ + + TW+ +++A ++G R+IGVSN+ + + L+ ++P +NQIE++
Sbjct: 167 DSERHRDARRWTWRALENALKMGQCRAIGVSNYELSHLRELLQFCDVKPAVNQIELHARF 226
Query: 644 TQEPLXAHCXSLGIAVMAYSPFG 712
Q L A C S+G+ V+ YSP G
Sbjct: 227 PQTELRAFCESVGVHVVGYSPLG 249
>UniRef50_Q4WUF7 Cluster: Aldo-keto reductase, putative; n=3;
Pezizomycotina|Rep: Aldo-keto reductase, putative -
Aspergillus fumigatus (Sartorya fumigata)
Length = 283
Score = 103 bits (247), Expect = 5e-21
Identities = 64/168 (38%), Positives = 94/168 (55%), Gaps = 3/168 (1%)
Frame = +2
Query: 212 AIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQ 391
A+EAGYRHIDTA Y +E++VG EA+ + R ++FVTTK+ + + + L
Sbjct: 42 ALEAGYRHIDTAQFYGNEKEVG----EALRKCGIPRSDVFVTTKILSPAGSPEATYQKLL 97
Query: 392 ESLKKLG--LDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFN 565
ES++K+G Y+DL+LIH S + E WQ ++ + G RSIGVSNF
Sbjct: 98 ESVEKIGGRDGYVDLFLIH-------SSSSGSAGRKELWQALERLLEEGKTRSIGVSNFG 150
Query: 566 ATQITRLVSNSYI-RPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSP 706
I + + + + P +NQIE++P Q + A+C GI V AYSP
Sbjct: 151 VKHIEEMKAYAKVWPPHVNQIELHPWCQQRVIEAYCKRNGIVVEAYSP 198
>UniRef50_Q2BBN7 Cluster: YvgN; n=1; Bacillus sp. NRRL B-14911|Rep:
YvgN - Bacillus sp. NRRL B-14911
Length = 268
Score = 103 bits (246), Expect = 6e-21
Identities = 67/207 (32%), Positives = 103/207 (49%), Gaps = 6/207 (2%)
Frame = +2
Query: 104 IQLHAGXPLPXVALGT---GRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQV 274
I L+ G +P V GT G+ + + + AIE GYR ID A +Y++EE V
Sbjct: 4 ITLNNGLEMPIVGTGTNTYGKENNDYNGDLTNEIPELASAIELGYRSIDAAIMYRNEELV 63
Query: 275 GQGIAEAIANGLVTREELFVTTKLWNDKH---ARDQVVPALQESLKKLGLDYIDLYLIHF 445
G +AE+ V REE F+TTK+ + +++ A+ SLK DY+DL LIHF
Sbjct: 64 GSVLAES----KVPREEFFITTKIPASEEYISSKEATRAAIDNSLKNFQTDYLDLLLIHF 119
Query: 446 PIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQI 625
PI D + TW+ ++ + G ++IGVSNF + L + ++P +NQI
Sbjct: 120 PIE-------DKVQLKNTWEVFEEYYEAGKLKAIGVSNFEENHLDELKEFAKVKPAVNQI 172
Query: 626 EVNPTNTQEPLXAHCXSLGIAVMAYSP 706
++N + L A I +A+ P
Sbjct: 173 QINLKEPNKNLLAVLKDEEITPVAWGP 199
>UniRef50_Q21274 Cluster: Putative uncharacterized protein; n=1;
Caenorhabditis elegans|Rep: Putative uncharacterized
protein - Caenorhabditis elegans
Length = 301
Score = 103 bits (246), Expect = 6e-21
Identities = 63/200 (31%), Positives = 103/200 (51%), Gaps = 5/200 (2%)
Frame = +2
Query: 119 GXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAI 298
G +P + LG R + + ++ A+++GYR DTA +Y++E +G + + +
Sbjct: 17 GYEMPKIGLGISRIETQQDLDV-----SIEAALKSGYRQFDTANLYKNETFLGNSLKKYL 71
Query: 299 ANGLVTREELFVTTKLWN-DKHARDQVVPALQESLKKLGLDYIDLYLIHFPI---ATKPD 466
+TRE++F+TTK+ +++ ++ L SL L DY+DL LIH+P D
Sbjct: 72 PQFGLTREDVFITTKVRTLNENTVEETEKQLANSLATLQTDYVDLLLIHYPRDRDTGNDD 131
Query: 467 DSPDNIDYLE-TWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTN 643
D N + WQ ++ A++ G RSIGVSN+ + + + IRPV+NQ E P
Sbjct: 132 DYEINKSRRKIVWQTLEKAKESGRVRSIGVSNYEVYHLVEMFEYAKIRPVLNQYEYQPYL 191
Query: 644 TQEPLXAHCXSLGIAVMAYS 703
T+ L C I V +YS
Sbjct: 192 TRPTLKKFCDLNNIVVQSYS 211
>UniRef50_Q9C1X5 Cluster: Xylose and arabinose reductase; n=1;
Schizosaccharomyces pombe|Rep: Xylose and arabinose
reductase - Schizosaccharomyces pombe (Fission yeast)
Length = 283
Score = 103 bits (246), Expect = 6e-21
Identities = 70/206 (33%), Positives = 107/206 (51%), Gaps = 1/206 (0%)
Frame = +2
Query: 92 QAPCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQ 271
++ + L G +P + G G K ++ V QA +++GYRHIDTAAVY +E+
Sbjct: 7 ESTTVTLTNGMVIPRI--GFGAFMLKYNECYGLVTQA----LDSGYRHIDTAAVYGNEDI 60
Query: 272 VGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPI 451
G+ I + V R ++F+T+KL N A++ SL LG YIDL+LI P
Sbjct: 61 CGKAIVDWCEKNNVKRTDIFLTSKLANCSDYY-STRAAIRSSLHHLG-TYIDLFLIQSPA 118
Query: 452 ATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRL-VSNSYIRPVINQIE 628
K + +W+ M++ G RS+GVSN+ + L SN P +NQIE
Sbjct: 119 GGKK-------SRIASWKAMEEFVDSGDIRSVGVSNYGVKHLQELYASNPKFYPCVNQIE 171
Query: 629 VNPTNTQEPLXAHCXSLGIAVMAYSP 706
++P +Q+ + +C S IA+ AYSP
Sbjct: 172 LHPFLSQDDIVKYCQSHDIAIEAYSP 197
>UniRef50_Q4P1G1 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 320
Score = 103 bits (246), Expect = 6e-21
Identities = 63/177 (35%), Positives = 99/177 (55%)
Frame = +2
Query: 98 PCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 277
P ++L +G LP +A GTG SD+ V A +++G+R ID A VY +E +G
Sbjct: 4 PTVRLASGLELPRLAFGTGTALYN-SDAAKQVTMA----LDSGFRFIDGAEVYANEASMG 58
Query: 278 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIAT 457
GI +A+ + R +++V TK+ K + A++ L+KL +D +D YL+H P
Sbjct: 59 AGIESFLASSGLKRNDIYVLTKV--GKEGMKDLQSAIKVELQKLKVDQLDSYLLHLPPRG 116
Query: 458 KPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIE 628
+ D P N+D W+ ++ +Q GL +SIGVSN+ A+ I +L+ P INQIE
Sbjct: 117 Q-DGLPSNVD---AWKELEKIKQAGLTKSIGVSNWLASDIQQLLDAGLSVPDINQIE 169
>UniRef50_A1CAM7 Cluster: Aldo-keto reductase, putative; n=9;
Dikarya|Rep: Aldo-keto reductase, putative - Aspergillus
clavatus
Length = 283
Score = 102 bits (245), Expect = 8e-21
Identities = 62/173 (35%), Positives = 97/173 (56%), Gaps = 3/173 (1%)
Frame = +2
Query: 197 QAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQV 376
Q+ A++AGYR+IDTA Y +E++VG EA+ + R ++FVTTK+ + + +
Sbjct: 37 QSCLTALQAGYRNIDTAQFYANEQEVG----EALRTSGIPRSDVFVTTKILSPAGSPEAT 92
Query: 377 VPALQESLKKLGLD--YIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIG 550
L ES++K+G + Y+DL+LIH S + E WQ ++ + G +SIG
Sbjct: 93 YKKLLESVEKIGGENGYVDLFLIH-------SSSSGSAGRKELWQALEKLLEEGKTKSIG 145
Query: 551 VSNFNATQITRLVSNSYI-RPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSP 706
VSNF I + + + + P +NQIE++P Q + A+C GI V AYSP
Sbjct: 146 VSNFGVKHIEEMKAYAKVWPPHVNQIELHPWCQQRVIDAYCKRNGIVVEAYSP 198
>UniRef50_UPI000065D0BD Cluster: Homolog of Homo sapiens "AKR1B1
protein.; n=1; Takifugu rubripes|Rep: Homolog of Homo
sapiens "AKR1B1 protein. - Takifugu rubripes
Length = 330
Score = 102 bits (244), Expect = 1e-20
Identities = 53/118 (44%), Positives = 72/118 (61%)
Frame = +2
Query: 98 PCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVG 277
P + L+ G +P + LGT K + +AV AI AGYRHIDTA VY++E +VG
Sbjct: 3 PSVTLNTGALMPVLGLGTW----KSGKGVTT--EAVKVAIGAGYRHIDTAYVYENETEVG 56
Query: 278 QGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPI 451
G+ I G+V REELF+ +KLW H V A +++L L LDY+DLYL+HFP+
Sbjct: 57 AGVQAMIDQGVVKREELFIVSKLWCTFHTPSLVRGACEKTLSSLNLDYVDLYLMHFPM 114
Score = 65.3 bits (152), Expect = 1e-09
Identities = 32/81 (39%), Positives = 49/81 (60%), Gaps = 2/81 (2%)
Frame = +2
Query: 476 DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI--RPVINQIEVNPTNTQ 649
D +L+TW+ M++ GLA++IG+SNFN QI +++ + +P NQIE +P Q
Sbjct: 158 DGTSFLDTWEAMEELVDDGLAKAIGISNFNKDQIEAVLNKPGLKHKPATNQIECHPHLNQ 217
Query: 650 EPLXAHCXSLGIAVMAYSPFG 712
E L C S GI+V A++ G
Sbjct: 218 EKLIHFCRSRGISVTAFACLG 238
>UniRef50_Q7VHE1 Cluster: Putative uncharacterized protein; n=1;
Helicobacter hepaticus|Rep: Putative uncharacterized
protein - Helicobacter hepaticus
Length = 270
Score = 102 bits (244), Expect = 1e-20
Identities = 67/202 (33%), Positives = 103/202 (50%)
Frame = +2
Query: 104 IQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 283
+ L+ G +P + LGT T K ++A+ AIE GYR D+A +Y +E ++G
Sbjct: 4 LTLNNGVKMPILGLGTYSLTGKAG------QKAMSEAIEVGYRLFDSAQMYNNEAELGAA 57
Query: 284 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 463
I A+ G + REE F+ TKL + + D ++++SLK LGLDYID LIH P +
Sbjct: 58 INAAVKGG-IKREEFFIQTKLL-ESSSEDLAKKSIEKSLKTLGLDYIDSLLIHMPYSQSK 115
Query: 464 DDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTN 643
++ M+ + G+ R IG+SNF A + V + + P INQ E +
Sbjct: 116 ----------AMYRAMESFYKQGILRVIGISNFGAKAYSEFVKSCEVIPAINQCETHLLL 165
Query: 644 TQEPLXAHCXSLGIAVMAYSPF 709
Q+PL S + ++SPF
Sbjct: 166 QQKPLREAMKSKKTLLQSWSPF 187
>UniRef50_Q03U37 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=5; Lactobacillus|Rep: Aldo/keto
reductase of diketogulonate reductase family -
Lactobacillus brevis (strain ATCC 367 / JCM 1170)
Length = 282
Score = 102 bits (244), Expect = 1e-20
Identities = 63/187 (33%), Positives = 100/187 (53%)
Frame = +2
Query: 152 GRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELF 331
G GT +D + A+ A +AGYR DTA +Y++E+ +G I + GL RE LF
Sbjct: 22 GFGTYLLNDQ-PTMNTAIQTAWDAGYRMFDTAMLYRNEDILGPAIQQL---GL-PREGLF 76
Query: 332 VTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGM 511
+T+K+ DQ + A++ SLK+L DY+DL LIH+P+ + +TW+ +
Sbjct: 77 LTSKVAEIVQGYDQTMKAVEGSLKRLQTDYLDLLLIHWPVREH---------FFDTWRAL 127
Query: 512 QDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEPLXAHCXSLGIAV 691
+ + G +SIGVSN+ + L + + PV+NQ+E +P Q+ L + I
Sbjct: 128 EQLKADGQVKSIGVSNYTIAHLELLATKAKEMPVVNQVEYHPYLNQQALADYDQEHDIVT 187
Query: 692 MAYSPFG 712
A+SP G
Sbjct: 188 EAWSPLG 194
>UniRef50_Q4FY75 Cluster: Aldo-keto reductase-like protein; n=5;
Trypanosomatidae|Rep: Aldo-keto reductase-like protein -
Leishmania major strain Friedlin
Length = 372
Score = 102 bits (244), Expect = 1e-20
Identities = 65/200 (32%), Positives = 96/200 (48%), Gaps = 23/200 (11%)
Frame = +2
Query: 182 IXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKH 361
+ AV +A+ GYRH+D A Y +E VG+ +A+A+ RE+LFVT+KLW
Sbjct: 42 VSEATDAVAFALSCGYRHVDCAKAYGNEAAVGEALAQALRTRCTRREDLFVTSKLWPTDQ 101
Query: 362 ARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP---------------DDSP---DNID 487
D V A + +L L LDY+DLYLIH+P+ + D +P ++
Sbjct: 102 HPDHVEAACRATLAALQLDYLDLYLIHWPVCMRHTPHWTSDEDRYPRHRDGTPAIDTSVT 161
Query: 488 YLETWQGMQDARQLGLARSIGVSNFNATQITRLV-----SNSYIRPVINQIEVNPTNTQE 652
L+TW M GL +SIG++N + LV + PV+NQ+E +P
Sbjct: 162 LLDTWTAMNRLVDRGLVKSIGLANCTTAHVNDLVKAVAEAKLAHLPVLNQVEHHPGIVDG 221
Query: 653 PLXAHCXSLGIAVMAYSPFG 712
L S + + AY P G
Sbjct: 222 DLIGCLGSHDMLMAAYCPLG 241
>UniRef50_Q0CK00 Cluster: Predicted protein; n=1; Aspergillus
terreus NIH2624|Rep: Predicted protein - Aspergillus
terreus (strain NIH 2624)
Length = 292
Score = 101 bits (243), Expect = 1e-20
Identities = 66/186 (35%), Positives = 96/186 (51%), Gaps = 6/186 (3%)
Frame = +2
Query: 98 PCIQLHAGXPLPXVALGTGRGTAKXSDSIXX---VRQAVYWAIEAGYRHIDTAAVYQDEE 268
P + L G +P + GTG K + + + + A+E G+ HID A Y E
Sbjct: 4 PALSLKDGNLVPILGFGTGTAWYKDDPNDPTNPELIEVLKAALEKGFHHIDAADSYGTER 63
Query: 269 QVGQGIAEAIANGLVTREELFVTTKL---WNDKHARDQVVPALQESLKKLGLDYIDLYLI 439
+VG I E+ G + RE+LF+TTK+ W D V AL SL++L LDY+DLYL+
Sbjct: 64 EVGIAIRES---G-IPREQLFITTKVLEGWKD------VPGALDASLERLQLDYVDLYLL 113
Query: 440 HFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVIN 619
H P P+ D W+G++ + G ARSIGVSNF + ++ + P IN
Sbjct: 114 HNPYVI-----PNLTDIQSAWKGLEAVKATGKARSIGVSNFQRNHLEAILETCSVVPAIN 168
Query: 620 QIEVNP 637
Q+E +P
Sbjct: 169 QLEYHP 174
>UniRef50_Q07551 Cluster: NADPH-dependent alpha-keto amide
reductase; n=4; Saccharomycetales|Rep: NADPH-dependent
alpha-keto amide reductase - Saccharomyces cerevisiae
(Baker's yeast)
Length = 312
Score = 101 bits (243), Expect = 1e-20
Identities = 69/209 (33%), Positives = 103/209 (49%), Gaps = 8/209 (3%)
Frame = +2
Query: 110 LHAGXPLPXVAL-GTGRGTAKXSD-----SIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQ 271
L+ G +P +A+ GTG K + S V Q VY G HID A +Y+ +
Sbjct: 10 LNNGNKIPAIAIIGTGTRWYKNEETDATFSNSLVEQIVYALKLPGIIHIDAAEIYRTYPE 69
Query: 272 VGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPI 451
VG+ A++ R +F+T K D L +LKK+G DY+DLYL+H P
Sbjct: 70 VGK----ALSLTEKPRNAIFLTDKYSPQIKMSDSPADGLDLALKKMGTDYVDLYLLHSPF 125
Query: 452 ATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEV 631
+K + + E W+ M+ + G A++IGVSNF + R++ + ++P +NQIE
Sbjct: 126 VSK---EVNGLSLEEAWKDMEQLYKSGKAKNIGVSNFAVEDLQRILKVAEVKPQVNQIEF 182
Query: 632 NP-TNTQEP-LXAHCXSLGIAVMAYSPFG 712
+P Q P + C I V AYSP G
Sbjct: 183 SPFLQNQTPGIYKFCQEHDILVEAYSPLG 211
>UniRef50_Q4PE96 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 293
Score = 101 bits (242), Expect = 2e-20
Identities = 66/174 (37%), Positives = 94/174 (54%), Gaps = 3/174 (1%)
Frame = +2
Query: 194 RQAVYWAIE-AGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLW-NDKHAR 367
+QA+ A + AGYRH+DTA Y++E G+ + E V R ELF TTK++ N+
Sbjct: 43 KQALLNAFDKAGYRHVDTARYYRNEADCGEAVRECS----VPRSELFYTTKVYLNEMGGG 98
Query: 368 DQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSI 547
+ A+++SL K GLDY+DL L+H P K L++W + + Q G RS+
Sbjct: 99 SKTRLAVEDSLAKAGLDYLDLVLLHAPDGGKK-------FRLDSWDTLTELVQEGKVRSL 151
Query: 548 GVSNFNATQITRLV-SNSYIRPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSP 706
GVSNF I L+ S + PV NQIE +P Q+ + A + I V AY P
Sbjct: 152 GVSNFGPHHIQELIDSKPKVLPVCNQIECHPFFAQKEVRAASEAHSIIVQAYCP 205
>UniRef50_Q14LA8 Cluster: Putative aldo/keto reductase
oxidoreductase protein; n=1; Spiroplasma citri|Rep:
Putative aldo/keto reductase oxidoreductase protein -
Spiroplasma citri
Length = 263
Score = 101 bits (241), Expect = 2e-20
Identities = 60/173 (34%), Positives = 93/173 (53%), Gaps = 3/173 (1%)
Frame = +2
Query: 197 QAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQV 376
+A+ A++ GY+ IDTA VYQ+EE VG+ I + + + RE++ + TK+W D
Sbjct: 19 EAIINALQNGYKIIDTAKVYQNEEIVGRAIKKYLNSNNQRREDIIIETKIWCDDVEAGNT 78
Query: 377 VPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQL---GLARSI 547
A+ ESLK+L + Y+D+ LIH P N+++ +T + + Q GL +
Sbjct: 79 TNAVLESLKRLNVTYLDIVLIHRP----------NLNFYKTIKAYVELLQCKAKGLINVV 128
Query: 548 GVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSP 706
GVSNF+ I L + P +NQIE NP N + +C + I V +YSP
Sbjct: 129 GVSNFDKDMIEILFEETGAYPNLNQIEFNPFNQRWDRVQYCQNKNILVQSYSP 181
>UniRef50_Q5V663 Cluster: Aldehyde reductase; n=6;
Halobacteriaceae|Rep: Aldehyde reductase - Haloarcula
marismortui (Halobacterium marismortui)
Length = 279
Score = 100 bits (240), Expect = 3e-20
Identities = 63/185 (34%), Positives = 92/185 (49%)
Frame = +2
Query: 152 GRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELF 331
G GT + D+ ++V A+EAGYRHIDTA Y +E VG GIA A V R+++F
Sbjct: 21 GLGTWQNEDA-EQCAESVRTALEAGYRHIDTAQAYDNESAVGDGIAAAD----VDRDDIF 75
Query: 332 VTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGM 511
+ TK+W + D V+ +ESL KLG+D +DL +H+ + P+ ET
Sbjct: 76 LATKVWISNLSHDDVIETTEESLDKLGVDSVDLLYVHWAAG---EYEPE-----ETLPAF 127
Query: 512 QDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEPLXAHCXSLGIAV 691
+ GL ++GVSNF + + NQ+E +P Q L H +
Sbjct: 128 DELVDRGLIDNVGVSNFEPHHVETAMDVLDAPVFANQVETHPFLQQSELREHAAEQDYEL 187
Query: 692 MAYSP 706
+AYSP
Sbjct: 188 VAYSP 192
>UniRef50_Q5UYI9 Cluster: Oxidoreductase; n=1; Haloarcula
marismortui|Rep: Oxidoreductase - Haloarcula marismortui
(Halobacterium marismortui)
Length = 264
Score = 99 bits (238), Expect = 6e-20
Identities = 58/174 (33%), Positives = 93/174 (53%)
Frame = +2
Query: 191 VRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARD 370
V+++V + GY H+DTA Y++E ++G+ +A+ RE++F+T+K+ +
Sbjct: 14 VQKSVRAGLNVGYAHVDTAEGYKNESEIGEALAD------YDREDVFLTSKVLPKHLDYE 67
Query: 371 QVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIG 550
V+ A + SL +LG DY+DLYL+H+P P S ET M G R++G
Sbjct: 68 SVIEACEASLDRLGTDYLDLYLVHWP---NPATS-----IRETMNAMATLHDQGKIRNVG 119
Query: 551 VSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
VSNF+A Q+ + + +NQIE +P NTQ+ + C V A +P G
Sbjct: 120 VSNFSAYQLGAAQHVADVPIAVNQIEYHPWNTQDQVVEFCRDTDTVVEAAAPLG 173
>UniRef50_Q7R2T6 Cluster: GLP_291_56367_57278; n=1; Giardia lamblia
ATCC 50803|Rep: GLP_291_56367_57278 - Giardia lamblia
ATCC 50803
Length = 303
Score = 99.5 bits (237), Expect = 7e-20
Identities = 60/187 (32%), Positives = 92/187 (49%), Gaps = 15/187 (8%)
Frame = +2
Query: 197 QAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGL--VTREELFVTTKLWNDKHARD 370
+A+ A++ GYRH D A Y +E +G+ E + V RE+L++ +KLW + H +
Sbjct: 19 EAIRSAVKLGYRHFDCAYRYGNERMIGEVFKEIFNDDSYGVKREDLWIVSKLWPNFHEPE 78
Query: 371 QVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPD-------------NIDYLETWQGM 511
+V + E+L+ L L+Y+D++L+H+P+A K D +TW+ M
Sbjct: 79 KVAYQISETLRDLQLEYLDVFLMHWPLAIKHLADRDYASSDGKGGTLLGTTPIRKTWEAM 138
Query: 512 QDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEPLXAHCXSLGIAV 691
+ R IGVSN + L+S I+P NQ E P + L C S GI V
Sbjct: 139 EACVDKKQTRFIGVSNMGTAMLVDLLSYCRIKPFTNQFESQPYFPNDRLIEFCNSNGIYV 198
Query: 692 MAYSPFG 712
AY P G
Sbjct: 199 TAYRPLG 205
>UniRef50_A7D6I8 Cluster: Aldo/keto reductase; n=1; Halorubrum
lacusprofundi ATCC 49239|Rep: Aldo/keto reductase -
Halorubrum lacusprofundi ATCC 49239
Length = 258
Score = 99.1 bits (236), Expect = 1e-19
Identities = 58/170 (34%), Positives = 86/170 (50%)
Frame = +2
Query: 197 QAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQV 376
+ V A+ GYRH+DTA +Y +E VG G+AE +A V R+E+ V TKLW D V
Sbjct: 17 EPVATALSLGYRHLDTARIYGNEAVVGDGLAEGLAASDVDRDEVTVATKLWVDDLGAADV 76
Query: 377 VPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVS 556
P +ES LG++ +DL +H +P + D ++ L + D + R +GVS
Sbjct: 77 GPTARESADLLGVETLDLLYVH-----RPRGAYDPVETLPALDRLVDEE---VVREVGVS 128
Query: 557 NFNATQITRLVSNSYIRPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSP 706
NF Q+ R + +Q E++P + L H G V+AYSP
Sbjct: 129 NFEVDQLDRAIDTLDAPLAAHQTELHPLFYRPELLEHAREHGYTVVAYSP 178
>UniRef50_A7D6Q0 Cluster: Aldo/keto reductase; n=1; Halorubrum
lacusprofundi ATCC 49239|Rep: Aldo/keto reductase -
Halorubrum lacusprofundi ATCC 49239
Length = 309
Score = 98.7 bits (235), Expect = 1e-19
Identities = 68/206 (33%), Positives = 107/206 (51%)
Frame = +2
Query: 89 VQAPCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEE 268
V P L +G LP + LGT A D I +V A+ +GY HIDTA Y +EE
Sbjct: 32 VTIPTQTLPSGDTLPALGLGT---YALDDDQIA---DSVRAALSSGYTHIDTAEGYHNEE 85
Query: 269 QVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFP 448
+G+ +AE R+++F+T+K+ + ++ + + SL++L DY+DLYLIH+P
Sbjct: 86 AIGEVLAE------YDRDDVFLTSKVLAKNLGYESLIQSCEASLERLETDYLDLYLIHWP 139
Query: 449 IATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIE 628
+P I E+ Q M + GL R++GVSNF+A Q++ S + +NQIE
Sbjct: 140 -------NPA-ISLRESLQAMAELHDRGLVRNVGVSNFSAYQLSCANHISEVPIAVNQIE 191
Query: 629 VNPTNTQEPLXAHCXSLGIAVMAYSP 706
+P + L +C + A +P
Sbjct: 192 FHPWFQRPNLVDYCHESDTVIEAAAP 217
>UniRef50_Q9X265 Cluster: Oxidoreductase, aldo/keto reductase
family; n=2; Thermotoga|Rep: Oxidoreductase, aldo/keto
reductase family - Thermotoga maritima
Length = 274
Score = 97.1 bits (231), Expect = 4e-19
Identities = 69/205 (33%), Positives = 106/205 (51%), Gaps = 9/205 (4%)
Frame = +2
Query: 119 GXPLPXVALGT-GRGTAKXSDSIXXVR--QAVYWAIEAGYRHIDTAAVY---QDEEQVGQ 280
G +P + LGT G G + D + + AI+ GY HIDTA Y EE +G+
Sbjct: 10 GEEIPALGLGTWGIGGFETPDYSRDEEMVELLKTAIKMGYTHIDTAEYYGGGHTEELIGK 69
Query: 281 GIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 460
I + RE+LF+ +K+W RD ++ +L+ +LK+L DY+DLYLIH+P
Sbjct: 70 AIKD------FRREDLFIVSKVWPTHLRRDDLLRSLENTLKRLDTDYVDLYLIHWP---- 119
Query: 461 PDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPT 640
+P+ I ET M + + GL R IGVSNF+ + +S S V +Q++ N
Sbjct: 120 ---NPE-IPLEETLSAMAEGVRQGLIRYIGVSNFDRRLLEEAISKSQEPIVCDQVKYNIE 175
Query: 641 N---TQEPLXAHCXSLGIAVMAYSP 706
+ ++ L C G+ ++AYSP
Sbjct: 176 DRDPERDGLLEFCQKNGVTLVAYSP 200
>UniRef50_Q9HM42 Cluster: Alcohol dehydrogenase related protein;
n=1; Thermoplasma acidophilum|Rep: Alcohol dehydrogenase
related protein - Thermoplasma acidophilum
Length = 284
Score = 97.1 bits (231), Expect = 4e-19
Identities = 65/200 (32%), Positives = 103/200 (51%), Gaps = 4/200 (2%)
Frame = +2
Query: 119 GXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAI 298
G + + +GT S+++ +R +A++ G IDTA +Y E+ VG+ I
Sbjct: 13 GRKVSVIGVGTWSLEGSRSENVRSIR----YALDHGVNFIDTAEMYGTEDIVGEAIKG-- 66
Query: 299 ANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPD 478
RE+LF+ TK+W A V+ + +ESLKKLG DY+DLY +H+P +P
Sbjct: 67 ----YRREDLFIATKVWPTHFAYHDVLKSCEESLKKLGTDYVDLYQLHWP-------NP- 114
Query: 479 NIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSN-SYIRPVINQIEVNPTNTQ-- 649
++ ET M+ G R IG+SNF+ ++ +S + R V NQ+E N +
Sbjct: 115 SVSIKETMSAMEKLVDEGRIRYIGISNFSVKEMKEAMSALAKYRIVSNQLEYNVATREIE 174
Query: 650 -EPLXAHCXSLGIAVMAYSP 706
E + C G+A++AYSP
Sbjct: 175 DEGIYDFCRKNGMAIIAYSP 194
>UniRef50_Q96JD6-2 Cluster: Isoform 2 of Q96JD6 ; n=4;
Catarrhini|Rep: Isoform 2 of Q96JD6 - Homo sapiens
(Human)
Length = 263
Score = 96.7 bits (230), Expect = 5e-19
Identities = 49/102 (48%), Positives = 63/102 (61%)
Frame = +2
Query: 158 GTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVT 337
G + S V +AV AI+AGYRH D A Y +E +VG GI I G V RE+LF+
Sbjct: 8 GLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDLFIA 67
Query: 338 TKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 463
TKLW H + V A ++SLK L L+Y+DLYLIH+P+ KP
Sbjct: 68 TKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKP 109
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 750,074,561
Number of Sequences: 1657284
Number of extensions: 14624133
Number of successful extensions: 44206
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 41657
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 43408
length of database: 575,637,011
effective HSP length: 99
effective length of database: 411,565,895
effective search space used: 60088620670
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
- SilkBase 1999-2023 -