Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P12_F_B15
(738 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
J04794-1|AAA51711.1| 325|Homo sapiens ALDR1 protein. 174 3e-43
CR457010-1|CAG33291.1| 325|Homo sapiens AKR1A1 protein. 174 3e-43
BT007003-1|AAP35649.1| 325|Homo sapiens aldo-keto reductase fam... 174 3e-43
BC005394-1|AAH05394.1| 325|Homo sapiens aldo-keto reductase fam... 174 3e-43
BC000670-1|AAH00670.1| 325|Homo sapiens aldo-keto reductase fam... 174 3e-43
AL355480-3|CAI22459.1| 325|Homo sapiens aldo-keto reductase fam... 174 3e-43
AF112485-1|AAF01260.1| 325|Homo sapiens aldehyde reductase prot... 174 3e-43
AF036683-1|AAB92369.1| 325|Homo sapiens aldehyde reductase prot... 174 3e-43
U05598-1|AAA20937.1| 323|Homo sapiens dihydrodiol dehydrogenase... 166 8e-41
S68330-1|AAD14013.1| 323|Homo sapiens chlordecone reductase hom... 166 8e-41
L32592-1|AAB38486.1| 323|Homo sapiens dihydrodiol dehydrogenase... 166 8e-41
BT006653-1|AAP35299.1| 323|Homo sapiens aldo-keto reductase fam... 166 8e-41
BC063574-1|AAH63574.1| 323|Homo sapiens aldo-keto reductase fam... 166 8e-41
BC007024-1|AAH07024.1| 323|Homo sapiens aldo-keto reductase fam... 166 8e-41
AL713867-1|CAI16408.1| 323|Homo sapiens aldo-keto reductase fam... 166 8e-41
AL391427-1|CAI14726.1| 323|Homo sapiens aldo-keto reductase fam... 166 8e-41
AB209017-1|BAD92254.1| 286|Homo sapiens aldo-keto reductase fam... 166 8e-41
AB032153-1|BAA92891.1| 323|Homo sapiens bile acid-binding prote... 166 8e-41
AB031084-1|BAA92884.1| 323|Homo sapiens bile acid-binding prote... 166 8e-41
AB021654-1|BAA36169.1| 323|Homo sapiens DD2/bile acid-binding p... 166 8e-41
U05861-1|AAA18115.1| 323|Homo sapiens hepatic dihydrodiol dehyd... 165 1e-40
U05684-1|AAA16227.1| 323|Homo sapiens dihydrodiol dehydrogenase... 165 1e-40
M86609-1|AAB02880.1| 323|Homo sapiens dihydrodiol dehydrogenase... 165 1e-40
BT007197-1|AAP35861.1| 323|Homo sapiens aldo-keto reductase fam... 165 1e-40
BC040210-1|AAH40210.1| 323|Homo sapiens aldo-keto reductase fam... 165 1e-40
BC020216-1|AAH20216.1| 323|Homo sapiens aldo-keto reductase fam... 165 1e-40
BC015490-1|AAH15490.1| 323|Homo sapiens aldo-keto reductase fam... 165 1e-40
AL713867-2|CAI16409.1| 323|Homo sapiens aldo-keto reductase fam... 165 1e-40
AB032150-1|BAA92886.1| 323|Homo sapiens 20 alph-hydroxysteroid ... 165 1e-40
AB031083-1|BAA92883.1| 323|Homo sapiens 20 alpha-hydroxysteroid... 165 1e-40
DQ269985-1|ABB76132.1| 323|Homo sapiens type II 3a-hydroxystero... 161 3e-39
D26124-1|BAA05121.1| 306|Homo sapiens dihydrodiol dehydrogenase... 160 5e-39
CR542203-1|CAG47000.1| 316|Homo sapiens AKR1B1 protein. 159 7e-39
AF149416-1|AAF07272.2| 323|Homo sapiens 3-alpha hydroxysteroid ... 159 7e-39
S68290-1|AAD14012.1| 320|Homo sapiens chlordecone reductase hom... 159 1e-38
J05017-1|AAA51714.1| 316|Homo sapiens ALDR1 protein. 158 2e-38
D17793-1|BAA04619.2| 325|Homo sapiens KIAA0119 protein. 158 2e-38
BT007286-1|AAP35950.1| 323|Homo sapiens aldo-keto reductase fam... 158 2e-38
BC019230-1|AAH19230.1| 323|Homo sapiens aldo-keto reductase fam... 158 2e-38
BC001479-1|AAH01479.1| 323|Homo sapiens aldo-keto reductase fam... 158 2e-38
AL391427-4|CAI14729.1| 323|Homo sapiens aldo-keto reductase fam... 158 2e-38
AB045829-1|BAA99542.1| 323|Homo sapiens 3alpha-hydroxysteroid d... 158 2e-38
AB032157-1|BAA92892.1| 323|Homo sapiens prostaglandin F synthas... 158 2e-38
AB018580-1|BAA88488.1| 323|Homo sapiens hluPGFS protein. 158 2e-38
S68287-1|AAD14010.1| 323|Homo sapiens chlordecone reductase pro... 158 2e-38
D26125-1|BAA05122.1| 321|Homo sapiens 3 alpha-hydroxysteroid/di... 158 2e-38
AL355303-2|CAI14202.1| 323|Homo sapiens aldo-keto reductase fam... 158 2e-38
AB032163-1|BAA92893.1| 323|Homo sapiens dihydrodiol dehydrogena... 158 2e-38
AB031085-1|BAA92885.1| 323|Homo sapiens dihydrodiol dehydrogena... 158 2e-38
X15414-1|CAA33460.1| 316|Homo sapiens protein ( Human mRNA for ... 157 3e-38
S68288-1|AAD14011.1| 323|Homo sapiens chlordecone reductase hom... 157 3e-38
M59783-1|AAA51712.1| 316|Homo sapiens aldose reductase protein. 157 3e-38
M34720-1|AAA35560.1| 316|Homo sapiens protein ( Human aldose re... 157 3e-38
M33375-1|AAA35658.1| 308|Homo sapiens protein ( Human chlordeco... 157 3e-38
L43839-1|AAB41916.1| 323|Homo sapiens 3-alpha-hydroxysteroid de... 157 3e-38
J05474-1|AAA51715.1| 316|Homo sapiens aldose reductase protein. 157 3e-38
J04795-1|AAA51713.1| 316|Homo sapiens ALDR1 protein. 157 3e-38
CR450351-1|CAG29347.1| 316|Homo sapiens AKR1B1 protein. 157 3e-38
BT019859-1|AAV38662.1| 316|Homo sapiens aldo-keto reductase fam... 157 3e-38
BC010391-1|AAH10391.1| 316|Homo sapiens aldo-keto reductase fam... 157 3e-38
BC000260-1|AAH00260.1| 316|Homo sapiens aldo-keto reductase fam... 157 3e-38
AF328729-1|AAN09721.1| 316|Homo sapiens CTCL tumor antigen HD-C... 157 3e-38
AF032455-1|AAB88851.1| 316|Homo sapiens aldose reductase protein. 157 3e-38
AB209796-1|BAD93033.1| 260|Homo sapiens aldo-keto reductase fam... 157 3e-38
BC020744-1|AAH20744.1| 323|Homo sapiens aldo-keto reductase fam... 157 4e-38
BC005387-1|AAH05387.1| 316|Homo sapiens aldo-keto reductase fam... 152 1e-36
U37100-1|AAC17469.1| 316|Homo sapiens aldose reductase-like pep... 151 2e-36
CR541801-1|CAG46600.1| 316|Homo sapiens AKR1B10 protein. 151 2e-36
BT006794-1|AAP35440.1| 316|Homo sapiens aldo-keto reductase fam... 151 2e-36
BC008837-1|AAH08837.1| 316|Homo sapiens aldo-keto reductase fam... 151 2e-36
AF052577-1|AAC36465.1| 316|Homo sapiens aldo-keto reductase pro... 151 2e-36
AF524864-1|AAO13380.1| 316|Homo sapiens aldo-ketoreductase prot... 149 1e-35
Z28339-1|CAA82193.1| 326|Homo sapiens delta 4-3-oxosteroid 5 be... 147 4e-35
BC130627-1|AAI30628.1| 326|Homo sapiens aldo-keto reductase fam... 147 4e-35
BC130625-1|AAI30626.1| 326|Homo sapiens aldo-keto reductase fam... 147 4e-35
AF283659-1|AAG39381.1| 326|Homo sapiens 5-beta steroid reductas... 147 4e-35
AL713867-3|CAI16410.1| 247|Homo sapiens aldo-keto reductase fam... 129 9e-30
AL355480-2|CAI22458.1| 147|Homo sapiens aldo-keto reductase fam... 118 2e-26
BC002862-1|AAH02862.1| 307|Homo sapiens AKR1CL2 protein protein. 110 4e-24
AF263242-1|AAK58523.1| 320|Homo sapiens aldo-keto reductase loo... 110 4e-24
AB055603-1|BAC54568.1| 307|Homo sapiens aldo-keto reductase rel... 110 4e-24
AL391427-2|CAI14727.1| 302|Homo sapiens aldo-keto reductase fam... 109 8e-24
AL355303-1|CAI14201.1| 302|Homo sapiens aldo-keto reductase fam... 109 8e-24
BC101205-1|AAI01206.1| 129|Homo sapiens aldo-keto reductase fam... 105 1e-22
BC101204-1|AAI01205.1| 129|Homo sapiens aldo-keto reductase fam... 105 1e-22
AK131335-1|BAD18494.1| 129|Homo sapiens protein ( Homo sapiens ... 105 1e-22
AB037902-1|BAA92887.1| 130|Homo sapiens truncated aldo-keto red... 100 6e-21
AB040822-1|BAC54567.1| 222|Homo sapiens aldo-keto reductase rel... 97 8e-20
AB040821-1|BAC54566.1| 263|Homo sapiens aldo-keto reductase rel... 97 8e-20
AB040820-1|BAC54565.1| 250|Homo sapiens aldo-keto reductase rel... 97 8e-20
AK058142-1|BAB71682.1| 146|Homo sapiens protein ( Homo sapiens ... 62 2e-09
Y16675-1|CAA76347.1| 330|Homo sapiens aflatoxin B1-aldehyde red... 52 3e-06
BT007347-1|AAP36011.1| 330|Homo sapiens aldo-keto reductase fam... 52 3e-06
BC013996-1|AAH13996.1| 330|Homo sapiens AKR7A2 protein protein. 52 3e-06
BC012171-1|AAH12171.1| 330|Homo sapiens AKR7A2 protein protein. 52 3e-06
BC011586-1|AAH11586.1| 330|Homo sapiens AKR7A2 protein protein. 52 3e-06
BC010852-1|AAH10852.1| 330|Homo sapiens AKR7A2 protein protein. 52 3e-06
BC007352-1|AAH07352.2| 358|Homo sapiens AKR7A2 protein protein. 52 3e-06
BC004111-1|AAH04111.3| 330|Homo sapiens AKR7A2 protein protein. 52 3e-06
AL035413-8|CAB72321.1| 330|Homo sapiens aldo-keto reductase fam... 52 3e-06
AF026947-1|AAC52104.1| 330|Homo sapiens aflatoxin aldehyde redu... 52 3e-06
AB028065-1|BAA88489.1| 67|Homo sapiens prostaglandin F synthas... 46 1e-04
AF040639-1|AAD02195.1| 331|Homo sapiens aflatoxin B1-aldehyde r... 43 0.001
BC042420-1|AAH42420.2| 331|Homo sapiens aldo-keto reductase fam... 42 0.003
BC031562-1|AAH31562.1| 331|Homo sapiens aldo-keto reductase fam... 42 0.003
AJ271799-1|CAC81076.1| 331|Homo sapiens aflatoxin B1 aldehyde r... 42 0.003
AB037905-2|BAA92890.1| 45|Homo sapiens truncated aldo-keto red... 41 0.004
BC025709-1|AAH25709.1| 331|Homo sapiens aldo-keto reductase fam... 41 0.005
AL035413-11|CAI22232.1| 331|Homo sapiens aldo-keto reductase fa... 41 0.005
AJ278012-1|CAC79668.1| 259|Homo sapiens aflatoxin B1 aldehyde r... 40 0.012
L35546-1|AAA65028.1| 274|Homo sapiens gamma-glutamylcysteine sy... 34 0.46
CR541833-1|CAG46632.1| 274|Homo sapiens GCLM protein. 34 0.46
BC041809-1|AAH41809.1| 274|Homo sapiens glutamate-cysteine liga... 34 0.46
AY773965-1|AAV28733.1| 274|Homo sapiens glutamate-cysteine liga... 34 0.46
AL117351-10|CAI22976.1| 274|Homo sapiens glutamate-cysteine lig... 34 0.46
AL049796-2|CAI21813.1| 274|Homo sapiens glutamate-cysteine liga... 34 0.46
BC117495-1|AAI17496.1| 905|Homo sapiens stonin 2 protein. 30 10.0
BC117493-1|AAI17494.1| 905|Homo sapiens stonin 2 protein. 30 10.0
BC069587-1|AAH69587.1| 904|Homo sapiens STON2 protein protein. 30 10.0
BC069502-1|AAH69502.1| 905|Homo sapiens stonin 2 protein. 30 10.0
BC069389-1|AAH69389.1| 905|Homo sapiens stonin 2 protein. 30 10.0
BC069359-1|AAH69359.1| 905|Homo sapiens stonin 2 protein. 30 10.0
AF449430-1|AAL47008.1| 905|Homo sapiens endocytosis protein HST... 30 10.0
AF380833-1|AAK76362.1| 886|Homo sapiens endocytosis protein HST... 30 10.0
AF255309-1|AAK57558.1| 702|Homo sapiens stonin 2 protein. 30 10.0
AB208948-1|BAD92185.1| 932|Homo sapiens Stonin 2 variant protein. 30 10.0
>J04794-1|AAA51711.1| 325|Homo sapiens ALDR1 protein.
Length = 325
Score = 174 bits (423), Expect = 3e-43
Identities = 89/218 (40%), Positives = 132/218 (60%), Gaps = 12/218 (5%)
Frame = +2
Query: 95 APCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQV 274
A C+ LH G +P + LGT + V+ AV +A+ GYRHID AA+Y +E ++
Sbjct: 3 ASCVLLHTGQKMPLIGLGTWKSEP------GQVKAAVKYALSVGYRHIDCAAIYGNEPEI 56
Query: 275 GQGIAEAIANG-LVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPI 451
G+ + E + G V REELFVT+KLWN KH + V PAL+++L L L+Y+DLYL+H+P
Sbjct: 57 GEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPY 116
Query: 452 ATKPDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNS 598
A + D+P D+ Y ETW+ ++ GL +++G+SNFN+ QI ++S +
Sbjct: 117 AFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVA 176
Query: 599 YIRPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+RP + Q+E +P Q L AHC + G+ V AYSP G
Sbjct: 177 SVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLG 214
>CR457010-1|CAG33291.1| 325|Homo sapiens AKR1A1 protein.
Length = 325
Score = 174 bits (423), Expect = 3e-43
Identities = 89/218 (40%), Positives = 132/218 (60%), Gaps = 12/218 (5%)
Frame = +2
Query: 95 APCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQV 274
A C+ LH G +P + LGT + V+ AV +A+ GYRHID AA+Y +E ++
Sbjct: 3 ASCVLLHTGQKMPLIGLGTWKSEP------GQVKAAVKYALSVGYRHIDCAAIYGNEPEI 56
Query: 275 GQGIAEAIANG-LVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPI 451
G+ + E + G V REELFVT+KLWN KH + V PAL+++L L L+Y+DLYL+H+P
Sbjct: 57 GEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPY 116
Query: 452 ATKPDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNS 598
A + D+P D+ Y ETW+ ++ GL +++G+SNFN+ QI ++S +
Sbjct: 117 AFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVA 176
Query: 599 YIRPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+RP + Q+E +P Q L AHC + G+ V AYSP G
Sbjct: 177 SVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLG 214
>BT007003-1|AAP35649.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 174 bits (423), Expect = 3e-43
Identities = 89/218 (40%), Positives = 132/218 (60%), Gaps = 12/218 (5%)
Frame = +2
Query: 95 APCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQV 274
A C+ LH G +P + LGT + V+ AV +A+ GYRHID AA+Y +E ++
Sbjct: 3 ASCVLLHTGQKMPLIGLGTWKSEP------GQVKAAVKYALSVGYRHIDCAAIYGNEPEI 56
Query: 275 GQGIAEAIANG-LVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPI 451
G+ + E + G V REELFVT+KLWN KH + V PAL+++L L L+Y+DLYL+H+P
Sbjct: 57 GEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPY 116
Query: 452 ATKPDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNS 598
A + D+P D+ Y ETW+ ++ GL +++G+SNFN+ QI ++S +
Sbjct: 117 AFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVA 176
Query: 599 YIRPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+RP + Q+E +P Q L AHC + G+ V AYSP G
Sbjct: 177 SVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLG 214
>BC005394-1|AAH05394.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 174 bits (423), Expect = 3e-43
Identities = 89/218 (40%), Positives = 132/218 (60%), Gaps = 12/218 (5%)
Frame = +2
Query: 95 APCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQV 274
A C+ LH G +P + LGT + V+ AV +A+ GYRHID AA+Y +E ++
Sbjct: 3 ASCVLLHTGQKMPLIGLGTWKSEP------GQVKAAVKYALSVGYRHIDCAAIYGNEPEI 56
Query: 275 GQGIAEAIANG-LVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPI 451
G+ + E + G V REELFVT+KLWN KH + V PAL+++L L L+Y+DLYL+H+P
Sbjct: 57 GEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPY 116
Query: 452 ATKPDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNS 598
A + D+P D+ Y ETW+ ++ GL +++G+SNFN+ QI ++S +
Sbjct: 117 AFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVA 176
Query: 599 YIRPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+RP + Q+E +P Q L AHC + G+ V AYSP G
Sbjct: 177 SVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLG 214
>BC000670-1|AAH00670.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 174 bits (423), Expect = 3e-43
Identities = 89/218 (40%), Positives = 132/218 (60%), Gaps = 12/218 (5%)
Frame = +2
Query: 95 APCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQV 274
A C+ LH G +P + LGT + V+ AV +A+ GYRHID AA+Y +E ++
Sbjct: 3 ASCVLLHTGQKMPLIGLGTWKSEP------GQVKAAVKYALSVGYRHIDCAAIYGNEPEI 56
Query: 275 GQGIAEAIANG-LVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPI 451
G+ + E + G V REELFVT+KLWN KH + V PAL+++L L L+Y+DLYL+H+P
Sbjct: 57 GEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPY 116
Query: 452 ATKPDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNS 598
A + D+P D+ Y ETW+ ++ GL +++G+SNFN+ QI ++S +
Sbjct: 117 AFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVA 176
Query: 599 YIRPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+RP + Q+E +P Q L AHC + G+ V AYSP G
Sbjct: 177 SVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLG 214
>AL355480-3|CAI22459.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehydetase, 1 protein.
Length = 325
Score = 174 bits (423), Expect = 3e-43
Identities = 89/218 (40%), Positives = 132/218 (60%), Gaps = 12/218 (5%)
Frame = +2
Query: 95 APCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQV 274
A C+ LH G +P + LGT + V+ AV +A+ GYRHID AA+Y +E ++
Sbjct: 3 ASCVLLHTGQKMPLIGLGTWKSEP------GQVKAAVKYALSVGYRHIDCAAIYGNEPEI 56
Query: 275 GQGIAEAIANG-LVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPI 451
G+ + E + G V REELFVT+KLWN KH + V PAL+++L L L+Y+DLYL+H+P
Sbjct: 57 GEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPY 116
Query: 452 ATKPDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNS 598
A + D+P D+ Y ETW+ ++ GL +++G+SNFN+ QI ++S +
Sbjct: 117 AFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVA 176
Query: 599 YIRPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+RP + Q+E +P Q L AHC + G+ V AYSP G
Sbjct: 177 SVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLG 214
>AF112485-1|AAF01260.1| 325|Homo sapiens aldehyde reductase
protein.
Length = 325
Score = 174 bits (423), Expect = 3e-43
Identities = 89/218 (40%), Positives = 132/218 (60%), Gaps = 12/218 (5%)
Frame = +2
Query: 95 APCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQV 274
A C+ LH G +P + LGT + V+ AV +A+ GYRHID AA+Y +E ++
Sbjct: 3 ASCVLLHTGQKMPLIGLGTWKSEP------GQVKAAVKYALSVGYRHIDCAAIYGNEPEI 56
Query: 275 GQGIAEAIANG-LVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPI 451
G+ + E + G V REELFVT+KLWN KH + V PAL+++L L L+Y+DLYL+H+P
Sbjct: 57 GEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPY 116
Query: 452 ATKPDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNS 598
A + D+P D+ Y ETW+ ++ GL +++G+SNFN+ QI ++S +
Sbjct: 117 AFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVA 176
Query: 599 YIRPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+RP + Q+E +P Q L AHC + G+ V AYSP G
Sbjct: 177 SVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLG 214
>AF036683-1|AAB92369.1| 325|Homo sapiens aldehyde reductase
protein.
Length = 325
Score = 174 bits (423), Expect = 3e-43
Identities = 89/218 (40%), Positives = 132/218 (60%), Gaps = 12/218 (5%)
Frame = +2
Query: 95 APCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQV 274
A C+ LH G +P + LGT + V+ AV +A+ GYRHID AA+Y +E ++
Sbjct: 3 ASCVLLHTGQKMPLIGLGTWKSEP------GQVKAAVKYALSVGYRHIDCAAIYGNEPEI 56
Query: 275 GQGIAEAIANG-LVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPI 451
G+ + E + G V REELFVT+KLWN KH + V PAL+++L L L+Y+DLYL+H+P
Sbjct: 57 GEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPY 116
Query: 452 ATKPDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNS 598
A + D+P D+ Y ETW+ ++ GL +++G+SNFN+ QI ++S +
Sbjct: 117 AFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVA 176
Query: 599 YIRPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+RP + Q+E +P Q L AHC + G+ V AYSP G
Sbjct: 177 SVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLG 214
>U05598-1|AAA20937.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 166 bits (403), Expect = 8e-41
Identities = 90/217 (41%), Positives = 126/217 (58%), Gaps = 13/217 (5%)
Frame = +2
Query: 101 CIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQ 280
C++L+ G +P + GT A +AV AIEAG+ HID+A VY +EEQVG
Sbjct: 7 CVKLNDGHFMPVLGFGT---YAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGL 63
Query: 281 GIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 460
I IA+G V RE++F T+KLW++ H + V PAL+ SLK L LDY+DLYLIHFP++ K
Sbjct: 64 AIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVK 123
Query: 461 PDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI- 604
P + D +D TW+ M+ + GLA+SIGVSNFN + +++ +
Sbjct: 124 PGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLK 183
Query: 605 -RPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+PV NQ+E +P Q L C S I ++AYS G
Sbjct: 184 YKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALG 220
>S68330-1|AAD14013.1| 323|Homo sapiens chlordecone reductase
homolog protein.
Length = 323
Score = 166 bits (403), Expect = 8e-41
Identities = 90/217 (41%), Positives = 126/217 (58%), Gaps = 13/217 (5%)
Frame = +2
Query: 101 CIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQ 280
C++L+ G +P + GT A +AV AIEAG+ HID+A VY +EEQVG
Sbjct: 7 CVKLNDGHFMPVLGFGT---YAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGL 63
Query: 281 GIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 460
I IA+G V RE++F T+KLW++ H + V PAL+ SLK L LDY+DLYLIHFP++ K
Sbjct: 64 AIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVK 123
Query: 461 PDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR 607
P + D +D TW+ M+ + GLA+SIGVSNFN + +++ ++
Sbjct: 124 PGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNEPGLK 183
Query: 608 --PVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
PV NQ+E +P Q L C S I ++AYS G
Sbjct: 184 YEPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALG 220
>L32592-1|AAB38486.1| 323|Homo sapiens dihydrodiol
dehydrogenase/bile acid-binding protein protein.
Length = 323
Score = 166 bits (403), Expect = 8e-41
Identities = 91/217 (41%), Positives = 125/217 (57%), Gaps = 13/217 (5%)
Frame = +2
Query: 101 CIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQ 280
C++L+ G +P + GT A +AV AIEAGY HID+A VY +EEQVG
Sbjct: 7 CVKLNDGHFMPVLGFGT---YAPAEVPKSKALEAVKLAIEAGYHHIDSAHVYNNEEQVGL 63
Query: 281 GIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 460
I IA+G V RE++F T+KLW++ H + V PAL+ SLK L LDY DLYLIHFP++ K
Sbjct: 64 AIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYADLYLIHFPVSVK 123
Query: 461 PDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR 607
P + D +D TW+ M+ + GLA+SIGVSNFN + +++ ++
Sbjct: 124 PGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNEPGLK 183
Query: 608 --PVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
PV NQ+E +P Q L C S I ++AYS G
Sbjct: 184 YEPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALG 220
>BT006653-1|AAP35299.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 166 bits (403), Expect = 8e-41
Identities = 90/217 (41%), Positives = 126/217 (58%), Gaps = 13/217 (5%)
Frame = +2
Query: 101 CIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQ 280
C++L+ G +P + GT A +AV AIEAG+ HID+A VY +EEQVG
Sbjct: 7 CVKLNDGHFMPVLGFGT---YAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGL 63
Query: 281 GIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 460
I IA+G V RE++F T+KLW++ H + V PAL+ SLK L LDY+DLYLIHFP++ K
Sbjct: 64 AIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVK 123
Query: 461 PDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI- 604
P + D +D TW+ M+ + GLA+SIGVSNFN + +++ +
Sbjct: 124 PGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLK 183
Query: 605 -RPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+PV NQ+E +P Q L C S I ++AYS G
Sbjct: 184 YKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALG 220
>BC063574-1|AAH63574.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 166 bits (403), Expect = 8e-41
Identities = 90/217 (41%), Positives = 126/217 (58%), Gaps = 13/217 (5%)
Frame = +2
Query: 101 CIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQ 280
C++L+ G +P + GT A +AV AIEAG+ HID+A VY +EEQVG
Sbjct: 7 CVKLNDGHFMPVLGFGT---YAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGL 63
Query: 281 GIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 460
I IA+G V RE++F T+KLW++ H + V PAL+ SLK L LDY+DLYLIHFP++ K
Sbjct: 64 AIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVK 123
Query: 461 PDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI- 604
P + D +D TW+ M+ + GLA+SIGVSNFN + +++ +
Sbjct: 124 PGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLK 183
Query: 605 -RPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+PV NQ+E +P Q L C S I ++AYS G
Sbjct: 184 YKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALG 220
>BC007024-1|AAH07024.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 166 bits (403), Expect = 8e-41
Identities = 90/217 (41%), Positives = 126/217 (58%), Gaps = 13/217 (5%)
Frame = +2
Query: 101 CIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQ 280
C++L+ G +P + GT A +AV AIEAG+ HID+A VY +EEQVG
Sbjct: 7 CVKLNDGHFMPVLGFGT---YAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGL 63
Query: 281 GIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 460
I IA+G V RE++F T+KLW++ H + V PAL+ SLK L LDY+DLYLIHFP++ K
Sbjct: 64 AIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVK 123
Query: 461 PDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI- 604
P + D +D TW+ M+ + GLA+SIGVSNFN + +++ +
Sbjct: 124 PGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLK 183
Query: 605 -RPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+PV NQ+E +P Q L C S I ++AYS G
Sbjct: 184 YKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALG 220
>AL713867-1|CAI16408.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 166 bits (403), Expect = 8e-41
Identities = 90/217 (41%), Positives = 126/217 (58%), Gaps = 13/217 (5%)
Frame = +2
Query: 101 CIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQ 280
C++L+ G +P + GT A +AV AIEAG+ HID+A VY +EEQVG
Sbjct: 7 CVKLNDGHFMPVLGFGT---YAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGL 63
Query: 281 GIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 460
I IA+G V RE++F T+KLW++ H + V PAL+ SLK L LDY+DLYLIHFP++ K
Sbjct: 64 AIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVK 123
Query: 461 PDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI- 604
P + D +D TW+ M+ + GLA+SIGVSNFN + +++ +
Sbjct: 124 PGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLK 183
Query: 605 -RPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+PV NQ+E +P Q L C S I ++AYS G
Sbjct: 184 YKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALG 220
>AL391427-1|CAI14726.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 166 bits (403), Expect = 8e-41
Identities = 90/217 (41%), Positives = 126/217 (58%), Gaps = 13/217 (5%)
Frame = +2
Query: 101 CIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQ 280
C++L+ G +P + GT A +AV AIEAG+ HID+A VY +EEQVG
Sbjct: 7 CVKLNDGHFMPVLGFGT---YAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGL 63
Query: 281 GIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 460
I IA+G V RE++F T+KLW++ H + V PAL+ SLK L LDY+DLYLIHFP++ K
Sbjct: 64 AIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVK 123
Query: 461 PDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI- 604
P + D +D TW+ M+ + GLA+SIGVSNFN + +++ +
Sbjct: 124 PGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLK 183
Query: 605 -RPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+PV NQ+E +P Q L C S I ++AYS G
Sbjct: 184 YKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALG 220
>AB209017-1|BAD92254.1| 286|Homo sapiens aldo-keto reductase family
1, member C2 variant protein.
Length = 286
Score = 166 bits (403), Expect = 8e-41
Identities = 90/217 (41%), Positives = 126/217 (58%), Gaps = 13/217 (5%)
Frame = +2
Query: 101 CIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQ 280
C++L+ G +P + GT A +AV AIEAG+ HID+A VY +EEQVG
Sbjct: 20 CVKLNDGHFMPVLGFGT---YAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGL 76
Query: 281 GIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 460
I IA+G V RE++F T+KLW++ H + V PAL+ SLK L LDY+DLYLIHFP++ K
Sbjct: 77 AIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVK 136
Query: 461 PDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI- 604
P + D +D TW+ M+ + GLA+SIGVSNFN + +++ +
Sbjct: 137 PGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLK 196
Query: 605 -RPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+PV NQ+E +P Q L C S I ++AYS G
Sbjct: 197 YKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALG 233
>AB032153-1|BAA92891.1| 323|Homo sapiens bile acid-binding protein
protein.
Length = 323
Score = 166 bits (403), Expect = 8e-41
Identities = 90/217 (41%), Positives = 126/217 (58%), Gaps = 13/217 (5%)
Frame = +2
Query: 101 CIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQ 280
C++L+ G +P + GT A +AV AIEAG+ HID+A VY +EEQVG
Sbjct: 7 CVKLNDGHFMPVLGFGT---YAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGL 63
Query: 281 GIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 460
I IA+G V RE++F T+KLW++ H + V PAL+ SLK L LDY+DLYLIHFP++ K
Sbjct: 64 AIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVK 123
Query: 461 PDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI- 604
P + D +D TW+ M+ + GLA+SIGVSNFN + +++ +
Sbjct: 124 PGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLK 183
Query: 605 -RPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+PV NQ+E +P Q L C S I ++AYS G
Sbjct: 184 YKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALG 220
>AB031084-1|BAA92884.1| 323|Homo sapiens bile acid-binding protein
protein.
Length = 323
Score = 166 bits (403), Expect = 8e-41
Identities = 90/217 (41%), Positives = 126/217 (58%), Gaps = 13/217 (5%)
Frame = +2
Query: 101 CIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQ 280
C++L+ G +P + GT A +AV AIEAG+ HID+A VY +EEQVG
Sbjct: 7 CVKLNDGHFMPVLGFGT---YAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGL 63
Query: 281 GIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 460
I IA+G V RE++F T+KLW++ H + V PAL+ SLK L LDY+DLYLIHFP++ K
Sbjct: 64 AIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVK 123
Query: 461 PDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI- 604
P + D +D TW+ M+ + GLA+SIGVSNFN + +++ +
Sbjct: 124 PGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLK 183
Query: 605 -RPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+PV NQ+E +P Q L C S I ++AYS G
Sbjct: 184 YKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALG 220
>AB021654-1|BAA36169.1| 323|Homo sapiens DD2/bile acid-binding
protein/AKR1C2/3alpha-hydroxysteroid dehydrogenase type
3 protein.
Length = 323
Score = 166 bits (403), Expect = 8e-41
Identities = 90/217 (41%), Positives = 126/217 (58%), Gaps = 13/217 (5%)
Frame = +2
Query: 101 CIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQ 280
C++L+ G +P + GT A +AV AIEAG+ HID+A VY +EEQVG
Sbjct: 7 CVKLNDGHFMPVLGFGT---YAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGL 63
Query: 281 GIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 460
I IA+G V RE++F T+KLW++ H + V PAL+ SLK L LDY+DLYLIHFP++ K
Sbjct: 64 AIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVK 123
Query: 461 PDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI- 604
P + D +D TW+ M+ + GLA+SIGVSNFN + +++ +
Sbjct: 124 PGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLK 183
Query: 605 -RPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+PV NQ+E +P Q L C S I ++AYS G
Sbjct: 184 YKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALG 220
>U05861-1|AAA18115.1| 323|Homo sapiens hepatic dihydrodiol
dehydrogenase protein.
Length = 323
Score = 165 bits (401), Expect = 1e-40
Identities = 89/217 (41%), Positives = 126/217 (58%), Gaps = 13/217 (5%)
Frame = +2
Query: 101 CIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQ 280
C++L+ G +P + GT A +A AIEAG+RHID+A +Y +EEQVG
Sbjct: 7 CVKLNDGHFMPVLGFGT---YAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGL 63
Query: 281 GIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 460
I IA+G V RE++F T+KLW + H + V PAL+ SLK L LDY+DLYLIHFP++ K
Sbjct: 64 AIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVK 123
Query: 461 PDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI- 604
P + D +D TW+ ++ + GLA+SIGVSNFN Q+ +++ +
Sbjct: 124 PGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLK 183
Query: 605 -RPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+PV NQ+E +P Q L C S I ++AYS G
Sbjct: 184 YKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALG 220
>U05684-1|AAA16227.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 165 bits (401), Expect = 1e-40
Identities = 89/217 (41%), Positives = 126/217 (58%), Gaps = 13/217 (5%)
Frame = +2
Query: 101 CIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQ 280
C++L+ G +P + GT A +A AIEAG+RHID+A +Y +EEQVG
Sbjct: 7 CVKLNDGHFMPVLGFGT---YAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGL 63
Query: 281 GIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 460
I IA+G V RE++F T+KLW + H + V PAL+ SLK L LDY+DLYLIHFP++ K
Sbjct: 64 AIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVK 123
Query: 461 PDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI- 604
P + D +D TW+ ++ + GLA+SIGVSNFN Q+ +++ +
Sbjct: 124 PGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLK 183
Query: 605 -RPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+PV NQ+E +P Q L C S I ++AYS G
Sbjct: 184 YKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALG 220
>M86609-1|AAB02880.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 165 bits (401), Expect = 1e-40
Identities = 89/217 (41%), Positives = 126/217 (58%), Gaps = 13/217 (5%)
Frame = +2
Query: 101 CIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQ 280
C++L+ G +P + GT A +A AIEAG+RHID+A +Y +EEQVG
Sbjct: 7 CVKLNDGHFMPVLGFGT---YAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGL 63
Query: 281 GIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 460
I IA+G V RE++F T+KLW + H + V PAL+ SLK L LDY+DLYLIHFP++ K
Sbjct: 64 AIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVK 123
Query: 461 PDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI- 604
P + D +D TW+ ++ + GLA+SIGVSNFN Q+ +++ +
Sbjct: 124 PGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLK 183
Query: 605 -RPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+PV NQ+E +P Q L C S I ++AYS G
Sbjct: 184 YKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALG 220
>BT007197-1|AAP35861.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 165 bits (401), Expect = 1e-40
Identities = 89/217 (41%), Positives = 126/217 (58%), Gaps = 13/217 (5%)
Frame = +2
Query: 101 CIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQ 280
C++L+ G +P + GT A +A AIEAG+RHID+A +Y +EEQVG
Sbjct: 7 CVKLNDGHFMPVLGFGT---YAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGL 63
Query: 281 GIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 460
I IA+G V RE++F T+KLW + H + V PAL+ SLK L LDY+DLYLIHFP++ K
Sbjct: 64 AIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVK 123
Query: 461 PDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI- 604
P + D +D TW+ ++ + GLA+SIGVSNFN Q+ +++ +
Sbjct: 124 PGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLK 183
Query: 605 -RPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+PV NQ+E +P Q L C S I ++AYS G
Sbjct: 184 YKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALG 220
>BC040210-1|AAH40210.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 165 bits (401), Expect = 1e-40
Identities = 89/217 (41%), Positives = 126/217 (58%), Gaps = 13/217 (5%)
Frame = +2
Query: 101 CIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQ 280
C++L+ G +P + GT A +A AIEAG+RHID+A +Y +EEQVG
Sbjct: 7 CVKLNDGHFMPVLGFGT---YAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGL 63
Query: 281 GIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 460
I IA+G V RE++F T+KLW + H + V PAL+ SLK L LDY+DLYLIHFP++ K
Sbjct: 64 AIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVK 123
Query: 461 PDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI- 604
P + D +D TW+ ++ + GLA+SIGVSNFN Q+ +++ +
Sbjct: 124 PGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLK 183
Query: 605 -RPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+PV NQ+E +P Q L C S I ++AYS G
Sbjct: 184 YKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALG 220
>BC020216-1|AAH20216.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 165 bits (401), Expect = 1e-40
Identities = 89/217 (41%), Positives = 126/217 (58%), Gaps = 13/217 (5%)
Frame = +2
Query: 101 CIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQ 280
C++L+ G +P + GT A +A AIEAG+RHID+A +Y +EEQVG
Sbjct: 7 CVKLNDGHFMPVLGFGT---YAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGL 63
Query: 281 GIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 460
I IA+G V RE++F T+KLW + H + V PAL+ SLK L LDY+DLYLIHFP++ K
Sbjct: 64 AIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVK 123
Query: 461 PDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI- 604
P + D +D TW+ ++ + GLA+SIGVSNFN Q+ +++ +
Sbjct: 124 PGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLK 183
Query: 605 -RPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+PV NQ+E +P Q L C S I ++AYS G
Sbjct: 184 YKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALG 220
>BC015490-1|AAH15490.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 165 bits (401), Expect = 1e-40
Identities = 89/217 (41%), Positives = 126/217 (58%), Gaps = 13/217 (5%)
Frame = +2
Query: 101 CIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQ 280
C++L+ G +P + GT A +A AIEAG+RHID+A +Y +EEQVG
Sbjct: 7 CVKLNDGHFMPVLGFGT---YAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGL 63
Query: 281 GIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 460
I IA+G V RE++F T+KLW + H + V PAL+ SLK L LDY+DLYLIHFP++ K
Sbjct: 64 AIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVK 123
Query: 461 PDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI- 604
P + D +D TW+ ++ + GLA+SIGVSNFN Q+ +++ +
Sbjct: 124 PGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLK 183
Query: 605 -RPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+PV NQ+E +P Q L C S I ++AYS G
Sbjct: 184 YKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALG 220
>AL713867-2|CAI16409.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 165 bits (401), Expect = 1e-40
Identities = 89/217 (41%), Positives = 126/217 (58%), Gaps = 13/217 (5%)
Frame = +2
Query: 101 CIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQ 280
C++L+ G +P + GT A +A AIEAG+RHID+A +Y +EEQVG
Sbjct: 7 CVKLNDGHFMPVLGFGT---YAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGL 63
Query: 281 GIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 460
I IA+G V RE++F T+KLW + H + V PAL+ SLK L LDY+DLYLIHFP++ K
Sbjct: 64 AIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVK 123
Query: 461 PDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI- 604
P + D +D TW+ ++ + GLA+SIGVSNFN Q+ +++ +
Sbjct: 124 PGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLK 183
Query: 605 -RPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+PV NQ+E +P Q L C S I ++AYS G
Sbjct: 184 YKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALG 220
>AB032150-1|BAA92886.1| 323|Homo sapiens 20 alph-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 165 bits (401), Expect = 1e-40
Identities = 89/217 (41%), Positives = 126/217 (58%), Gaps = 13/217 (5%)
Frame = +2
Query: 101 CIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQ 280
C++L+ G +P + GT A +A AIEAG+RHID+A +Y +EEQVG
Sbjct: 7 CVKLNDGHFMPVLGFGT---YAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGL 63
Query: 281 GIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 460
I IA+G V RE++F T+KLW + H + V PAL+ SLK L LDY+DLYLIHFP++ K
Sbjct: 64 AIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVK 123
Query: 461 PDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI- 604
P + D +D TW+ ++ + GLA+SIGVSNFN Q+ +++ +
Sbjct: 124 PGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLK 183
Query: 605 -RPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+PV NQ+E +P Q L C S I ++AYS G
Sbjct: 184 YKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALG 220
>AB031083-1|BAA92883.1| 323|Homo sapiens 20 alpha-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 165 bits (401), Expect = 1e-40
Identities = 89/217 (41%), Positives = 126/217 (58%), Gaps = 13/217 (5%)
Frame = +2
Query: 101 CIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQ 280
C++L+ G +P + GT A +A AIEAG+RHID+A +Y +EEQVG
Sbjct: 7 CVKLNDGHFMPVLGFGT---YAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGL 63
Query: 281 GIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 460
I IA+G V RE++F T+KLW + H + V PAL+ SLK L LDY+DLYLIHFP++ K
Sbjct: 64 AIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVK 123
Query: 461 PDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI- 604
P + D +D TW+ ++ + GLA+SIGVSNFN Q+ +++ +
Sbjct: 124 PGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLK 183
Query: 605 -RPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+PV NQ+E +P Q L C S I ++AYS G
Sbjct: 184 YKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALG 220
>DQ269985-1|ABB76132.1| 323|Homo sapiens type II 3a-hydroxysteroid
dehydrogenase variant protein.
Length = 323
Score = 161 bits (390), Expect = 3e-39
Identities = 89/217 (41%), Positives = 127/217 (58%), Gaps = 13/217 (5%)
Frame = +2
Query: 101 CIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQ 280
C++L+ G +P + GT A +A AIEAG+RHID+A +Y +EEQVG
Sbjct: 7 CVKLNDGHFMPVLGFGT---YAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGL 63
Query: 281 GIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 460
+ IA+G V RE++F T+KLW + H + V PAL+ SLKK LDY+DLYLIH P++ K
Sbjct: 64 AVRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKKAQLDYVDLYLIHSPMSLK 123
Query: 461 PDD--SP---------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI- 604
P + SP D +D TW+ M+ + GLA+SIGVSNFN Q+ +++ +
Sbjct: 124 PGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLK 183
Query: 605 -RPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+PV NQ+E +P + L C S I ++AYS G
Sbjct: 184 YKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALG 220
>D26124-1|BAA05121.1| 306|Homo sapiens dihydrodiol dehydrogenase
isoform DD1 protein.
Length = 306
Score = 160 bits (388), Expect = 5e-39
Identities = 82/185 (44%), Positives = 114/185 (61%), Gaps = 13/185 (7%)
Frame = +2
Query: 197 QAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQV 376
+A AIEAG+RHID+A +Y +EEQVG I IA+G V RE++F T+KLW + H + V
Sbjct: 19 EATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELV 78
Query: 377 VPALQESLKKLGLDYIDLYLIHFPIATKPDDSP-----------DNIDYLETWQGMQDAR 523
PAL+ SLK L LDY+DLYLIHFP++ KP + D +D TW+ ++ +
Sbjct: 79 RPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCK 138
Query: 524 QLGLARSIGVSNFNATQITRLVSNSYI--RPVINQIEVNPTNTQEPLXAHCXSLGIAVMA 697
GLA+SIGVSNFN Q+ +++ + +PV NQ+E +P Q L C S I ++A
Sbjct: 139 DAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVA 198
Query: 698 YSPFG 712
YS G
Sbjct: 199 YSALG 203
>CR542203-1|CAG47000.1| 316|Homo sapiens AKR1B1 protein.
Length = 316
Score = 159 bits (387), Expect = 7e-39
Identities = 90/214 (42%), Positives = 125/214 (58%), Gaps = 13/214 (6%)
Frame = +2
Query: 110 LHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 289
L+ G +P + LGT + V +AV AI+ GYRHID A VYQ+E +VG I
Sbjct: 7 LNNGAKMPILGLGTWKSPP------GQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQ 60
Query: 290 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP-- 463
E + +V REELF+ +KLW H + V A Q++L L LDY+DLYLIH+PI KP
Sbjct: 61 EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPIGFKPGK 120
Query: 464 -----DDS----PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI--RP 610
D+S P + + L+TW M++ GL ++IG+SNFN Q+ +++ + +P
Sbjct: 121 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP 180
Query: 611 VINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+NQIE +P TQE L +C S GI V AYSP G
Sbjct: 181 AVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLG 214
>AF149416-1|AAF07272.2| 323|Homo sapiens 3-alpha hydroxysteroid
dehydrogenase type IIb protein.
Length = 323
Score = 159 bits (387), Expect = 7e-39
Identities = 89/217 (41%), Positives = 126/217 (58%), Gaps = 13/217 (5%)
Frame = +2
Query: 101 CIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQ 280
C++L+ G +P + GT V + AIEAG+RHID+A +Y +EEQVG
Sbjct: 7 CVKLNDGHFMPVLGFGTYAPPEVPRSKALEVSKL---AIEAGFRHIDSAHLYNNEEQVGL 63
Query: 281 GIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 460
I IA+G V RE++F T+KLW+ H + V PAL+ SLKK LDY+DLYLIH P++ K
Sbjct: 64 AIRSKIADGSVKREDIFYTSKLWSTSHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLK 123
Query: 461 PDD--SP---------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI- 604
P + SP D +D TW+ M+ + GLA+SIGVSNFN Q+ +++ +
Sbjct: 124 PGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLK 183
Query: 605 -RPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+PV NQ+E +P + L C S I ++AYS G
Sbjct: 184 YKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALG 220
>S68290-1|AAD14012.1| 320|Homo sapiens chlordecone reductase
homolog protein.
Length = 320
Score = 159 bits (385), Expect = 1e-38
Identities = 86/217 (39%), Positives = 124/217 (57%), Gaps = 13/217 (5%)
Frame = +2
Query: 101 CIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQ 280
C++L+ G +P + GT A +A AIEAG+RHID+A +Y +EEQVG
Sbjct: 4 CVKLNDGHFMPVLGFGT---YAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGL 60
Query: 281 GIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 460
I IA+G V RE++F T+KLW + H + PAL+ SLK L LDY+DLYLIHFP++ K
Sbjct: 61 AIRSKIADGSVKREDIFYTSKLWCNSHRPELDRPALERSLKNLQLDYVDLYLIHFPVSVK 120
Query: 461 PDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNS--Y 601
P + D +D TW+ ++ + LA+SIGVSNFN + + +++
Sbjct: 121 PGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAELAKSIGVSNFNRSTLEMILNKPGLQ 180
Query: 602 IRPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
++PV NQ+E +P Q L C S I ++AYS G
Sbjct: 181 VKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALG 217
>J05017-1|AAA51714.1| 316|Homo sapiens ALDR1 protein.
Length = 316
Score = 158 bits (384), Expect = 2e-38
Identities = 90/216 (41%), Positives = 125/216 (57%), Gaps = 13/216 (6%)
Frame = +2
Query: 104 IQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 283
I L+ G +P + LGT + V +AV AI+ GYRHID A VYQ+E +VG
Sbjct: 5 ILLNNGAKMPILGLGTWKSPP------GQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVA 58
Query: 284 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 463
I E + +V REELF+ +KLW H + V A Q++L L LDY+DLYLIH+P KP
Sbjct: 59 IQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKP 118
Query: 464 -------DDS----PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI-- 604
D+S P + + L+TW M++ GL ++IG+SNFN Q+ +++ +
Sbjct: 119 GKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKY 178
Query: 605 RPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+P +NQIE +P TQE L +C S GI V AYSP G
Sbjct: 179 KPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLG 214
>D17793-1|BAA04619.2| 325|Homo sapiens KIAA0119 protein.
Length = 325
Score = 158 bits (384), Expect = 2e-38
Identities = 89/217 (41%), Positives = 126/217 (58%), Gaps = 13/217 (5%)
Frame = +2
Query: 101 CIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQ 280
C++L+ G +P + GT V + AIEAG+RHID+A +Y +EEQVG
Sbjct: 9 CVKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKL---AIEAGFRHIDSAHLYNNEEQVGL 65
Query: 281 GIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 460
I IA+G V RE++F T+KLW+ H + V PAL+ SLKK LDY+DLYLIH P++ K
Sbjct: 66 AIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLK 125
Query: 461 PDD--SP---------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI- 604
P + SP D +D TW+ M+ + GLA+SIGVSNFN Q+ +++ +
Sbjct: 126 PGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLK 185
Query: 605 -RPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+PV NQ+E +P + L C S I ++AYS G
Sbjct: 186 YKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALG 222
>BT007286-1|AAP35950.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 158 bits (384), Expect = 2e-38
Identities = 89/217 (41%), Positives = 126/217 (58%), Gaps = 13/217 (5%)
Frame = +2
Query: 101 CIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQ 280
C++L+ G +P + GT V + AIEAG+RHID+A +Y +EEQVG
Sbjct: 7 CVKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKL---AIEAGFRHIDSAHLYNNEEQVGL 63
Query: 281 GIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 460
I IA+G V RE++F T+KLW+ H + V PAL+ SLKK LDY+DLYLIH P++ K
Sbjct: 64 AIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLK 123
Query: 461 PDD--SP---------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI- 604
P + SP D +D TW+ M+ + GLA+SIGVSNFN Q+ +++ +
Sbjct: 124 PGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLK 183
Query: 605 -RPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+PV NQ+E +P + L C S I ++AYS G
Sbjct: 184 YKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALG 220
>BC019230-1|AAH19230.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 158 bits (384), Expect = 2e-38
Identities = 89/217 (41%), Positives = 126/217 (58%), Gaps = 13/217 (5%)
Frame = +2
Query: 101 CIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQ 280
C++L+ G +P + GT V + AIEAG+RHID+A +Y +EEQVG
Sbjct: 7 CVKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKL---AIEAGFRHIDSAHLYNNEEQVGL 63
Query: 281 GIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 460
I IA+G V RE++F T+KLW+ H + V PAL+ SLKK LDY+DLYLIH P++ K
Sbjct: 64 AIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLK 123
Query: 461 PDD--SP---------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI- 604
P + SP D +D TW+ M+ + GLA+SIGVSNFN Q+ +++ +
Sbjct: 124 PGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLK 183
Query: 605 -RPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+PV NQ+E +P + L C S I ++AYS G
Sbjct: 184 YKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALG 220
>BC001479-1|AAH01479.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 158 bits (384), Expect = 2e-38
Identities = 89/217 (41%), Positives = 126/217 (58%), Gaps = 13/217 (5%)
Frame = +2
Query: 101 CIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQ 280
C++L+ G +P + GT V + AIEAG+RHID+A +Y +EEQVG
Sbjct: 7 CVKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKL---AIEAGFRHIDSAHLYNNEEQVGL 63
Query: 281 GIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 460
I IA+G V RE++F T+KLW+ H + V PAL+ SLKK LDY+DLYLIH P++ K
Sbjct: 64 AIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLK 123
Query: 461 PDD--SP---------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI- 604
P + SP D +D TW+ M+ + GLA+SIGVSNFN Q+ +++ +
Sbjct: 124 PGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLK 183
Query: 605 -RPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+PV NQ+E +P + L C S I ++AYS G
Sbjct: 184 YKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALG 220
>AL391427-4|CAI14729.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 158 bits (384), Expect = 2e-38
Identities = 89/217 (41%), Positives = 126/217 (58%), Gaps = 13/217 (5%)
Frame = +2
Query: 101 CIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQ 280
C++L+ G +P + GT V + AIEAG+RHID+A +Y +EEQVG
Sbjct: 7 CVKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKL---AIEAGFRHIDSAHLYNNEEQVGL 63
Query: 281 GIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 460
I IA+G V RE++F T+KLW+ H + V PAL+ SLKK LDY+DLYLIH P++ K
Sbjct: 64 AIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLK 123
Query: 461 PDD--SP---------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI- 604
P + SP D +D TW+ M+ + GLA+SIGVSNFN Q+ +++ +
Sbjct: 124 PGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLK 183
Query: 605 -RPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+PV NQ+E +P + L C S I ++AYS G
Sbjct: 184 YKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALG 220
>AB045829-1|BAA99542.1| 323|Homo sapiens 3alpha-hydroxysteroid
dehydrogenase variant protein.
Length = 323
Score = 158 bits (384), Expect = 2e-38
Identities = 88/216 (40%), Positives = 125/216 (57%), Gaps = 13/216 (6%)
Frame = +2
Query: 104 IQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 283
++L+ G +P + GT + V + AIEAG+RHID+A +Y +EEQVG
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKL---AIEAGFRHIDSAYLYNNEEQVGLA 64
Query: 284 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 463
I IA+G V RE++F T+KLW V PAL+ SLKKL LDY+DLYL+HFP+A KP
Sbjct: 65 IRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKP 124
Query: 464 DDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI-- 604
++P D +D TW+ M+ + GLA+SIGVSNFN Q+ +++ +
Sbjct: 125 GETPLPKDENGKVIFDTVDLCATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKY 184
Query: 605 RPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+PV NQ+E +P Q L C S I ++A+S G
Sbjct: 185 KPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALG 220
>AB032157-1|BAA92892.1| 323|Homo sapiens prostaglandin F synthase
protein.
Length = 323
Score = 158 bits (384), Expect = 2e-38
Identities = 89/217 (41%), Positives = 126/217 (58%), Gaps = 13/217 (5%)
Frame = +2
Query: 101 CIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQ 280
C++L+ G +P + GT V + AIEAG+RHID+A +Y +EEQVG
Sbjct: 7 CVKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKL---AIEAGFRHIDSAHLYNNEEQVGL 63
Query: 281 GIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 460
I IA+G V RE++F T+KLW+ H + V PAL+ SLKK LDY+DLYLIH P++ K
Sbjct: 64 AIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLK 123
Query: 461 PDD--SP---------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI- 604
P + SP D +D TW+ M+ + GLA+SIGVSNFN Q+ +++ +
Sbjct: 124 PGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLK 183
Query: 605 -RPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+PV NQ+E +P + L C S I ++AYS G
Sbjct: 184 YKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALG 220
>AB018580-1|BAA88488.1| 323|Homo sapiens hluPGFS protein.
Length = 323
Score = 158 bits (384), Expect = 2e-38
Identities = 89/217 (41%), Positives = 126/217 (58%), Gaps = 13/217 (5%)
Frame = +2
Query: 101 CIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQ 280
C++L+ G +P + GT V + AIEAG+RHID+A +Y +EEQVG
Sbjct: 7 CVKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKL---AIEAGFRHIDSAHLYNNEEQVGL 63
Query: 281 GIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 460
I IA+G V RE++F T+KLW+ H + V PAL+ SLKK LDY+DLYLIH P++ K
Sbjct: 64 AIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLK 123
Query: 461 PDD--SP---------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI- 604
P + SP D +D TW+ M+ + GLA+SIGVSNFN Q+ +++ +
Sbjct: 124 PGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLK 183
Query: 605 -RPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+PV NQ+E +P + L C S I ++AYS G
Sbjct: 184 YKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALG 220
>S68287-1|AAD14010.1| 323|Homo sapiens chlordecone reductase
protein.
Length = 323
Score = 158 bits (383), Expect = 2e-38
Identities = 88/216 (40%), Positives = 125/216 (57%), Gaps = 13/216 (6%)
Frame = +2
Query: 104 IQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 283
++L+ G +P + GT + V + AIEAG+RHID+A +Y +EEQVG
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKL---AIEAGFRHIDSAYLYNNEEQVGLA 64
Query: 284 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 463
I IA+G V RE++F T+KLW V PAL+ SLKKL LDY+DLYL+HFP+A KP
Sbjct: 65 IRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKP 124
Query: 464 DDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI-- 604
++P D +D TW+ M+ + GLA+SIGVSNFN Q+ +++ +
Sbjct: 125 GETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKY 184
Query: 605 RPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+PV NQ+E +P Q L C S I ++A+S G
Sbjct: 185 KPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALG 220
>D26125-1|BAA05122.1| 321|Homo sapiens 3
alpha-hydroxysteroid/dihydrodiol dehydrogenase DD4
protein.
Length = 321
Score = 158 bits (383), Expect = 2e-38
Identities = 88/216 (40%), Positives = 125/216 (57%), Gaps = 13/216 (6%)
Frame = +2
Query: 104 IQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 283
++L+ G +P + GT + V + AIEAG+RHID+A +Y +EEQVG
Sbjct: 6 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKL---AIEAGFRHIDSAYLYNNEEQVGLA 62
Query: 284 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 463
I IA+G V RE++F T+KLW V PAL+ SLKKL LDY+DLYL+HFP+A KP
Sbjct: 63 IRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKP 122
Query: 464 DDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI-- 604
++P D +D TW+ M+ + GLA+SIGVSNFN Q+ +++ +
Sbjct: 123 GETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKY 182
Query: 605 RPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+PV NQ+E +P Q L C S I ++A+S G
Sbjct: 183 KPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALG 218
>AL355303-2|CAI14202.1| 323|Homo sapiens aldo-keto reductase family
1, member C4 (chlordecone reductase; 3-alpha hydroxy
protein.
Length = 323
Score = 158 bits (383), Expect = 2e-38
Identities = 88/216 (40%), Positives = 125/216 (57%), Gaps = 13/216 (6%)
Frame = +2
Query: 104 IQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 283
++L+ G +P + GT + V + AIEAG+RHID+A +Y +EEQVG
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKL---AIEAGFRHIDSAYLYNNEEQVGLA 64
Query: 284 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 463
I IA+G V RE++F T+KLW V PAL+ SLKKL LDY+DLYL+HFP+A KP
Sbjct: 65 IRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKP 124
Query: 464 DDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI-- 604
++P D +D TW+ M+ + GLA+SIGVSNFN Q+ +++ +
Sbjct: 125 GETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKY 184
Query: 605 RPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+PV NQ+E +P Q L C S I ++A+S G
Sbjct: 185 KPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALG 220
>AB032163-1|BAA92893.1| 323|Homo sapiens dihydrodiol dehydrogenase
4 protein.
Length = 323
Score = 158 bits (383), Expect = 2e-38
Identities = 88/216 (40%), Positives = 125/216 (57%), Gaps = 13/216 (6%)
Frame = +2
Query: 104 IQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 283
++L+ G +P + GT + V + AIEAG+RHID+A +Y +EEQVG
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKL---AIEAGFRHIDSAYLYNNEEQVGLA 64
Query: 284 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 463
I IA+G V RE++F T+KLW V PAL+ SLKKL LDY+DLYL+HFP+A KP
Sbjct: 65 IRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKP 124
Query: 464 DDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI-- 604
++P D +D TW+ M+ + GLA+SIGVSNFN Q+ +++ +
Sbjct: 125 GETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKY 184
Query: 605 RPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+PV NQ+E +P Q L C S I ++A+S G
Sbjct: 185 KPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALG 220
>AB031085-1|BAA92885.1| 323|Homo sapiens dihydrodiol dehydrogenase
4 protein.
Length = 323
Score = 158 bits (383), Expect = 2e-38
Identities = 88/216 (40%), Positives = 125/216 (57%), Gaps = 13/216 (6%)
Frame = +2
Query: 104 IQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 283
++L+ G +P + GT + V + AIEAG+RHID+A +Y +EEQVG
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKL---AIEAGFRHIDSAYLYNNEEQVGLA 64
Query: 284 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 463
I IA+G V RE++F T+KLW V PAL+ SLKKL LDY+DLYL+HFP+A KP
Sbjct: 65 IRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKP 124
Query: 464 DDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI-- 604
++P D +D TW+ M+ + GLA+SIGVSNFN Q+ +++ +
Sbjct: 125 GETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKY 184
Query: 605 RPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+PV NQ+E +P Q L C S I ++A+S G
Sbjct: 185 KPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALG 220
>X15414-1|CAA33460.1| 316|Homo sapiens protein ( Human mRNA for
aldose reductase (EC 1.1.1.2). ).
Length = 316
Score = 157 bits (382), Expect = 3e-38
Identities = 89/214 (41%), Positives = 124/214 (57%), Gaps = 13/214 (6%)
Frame = +2
Query: 110 LHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 289
L+ G +P + LGT + V +AV AI+ GYRHID A VYQ+E +VG I
Sbjct: 7 LNNGAKMPILGLGTWKSPP------GQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQ 60
Query: 290 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP-- 463
E + +V REELF+ +KLW H + V A Q++L L LDY+DLYLIH+P KP
Sbjct: 61 EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK 120
Query: 464 -----DDS----PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI--RP 610
D+S P + + L+TW M++ GL ++IG+SNFN Q+ +++ + +P
Sbjct: 121 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP 180
Query: 611 VINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+NQIE +P TQE L +C S GI V AYSP G
Sbjct: 181 AVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLG 214
>S68288-1|AAD14011.1| 323|Homo sapiens chlordecone reductase
homolog protein.
Length = 323
Score = 157 bits (382), Expect = 3e-38
Identities = 89/217 (41%), Positives = 126/217 (58%), Gaps = 13/217 (5%)
Frame = +2
Query: 101 CIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQ 280
C++L+ G +P + GT V + AIEAG+RHID+A +Y +EEQVG
Sbjct: 7 CVKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKL---AIEAGFRHIDSAHLYNNEEQVGL 63
Query: 281 GIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 460
I IA+G V RE++F T+KLW+ H + V PAL+ SLKK LDY+DLYLIH P++ K
Sbjct: 64 AIRSKIADGSVEREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLK 123
Query: 461 PDD--SP---------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI- 604
P + SP D +D TW+ M+ + GLA+SIGVSNFN Q+ +++ +
Sbjct: 124 PGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEIILNKPGLK 183
Query: 605 -RPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+PV NQ+E +P + L C S I ++AYS G
Sbjct: 184 YKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALG 220
>M59783-1|AAA51712.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 157 bits (382), Expect = 3e-38
Identities = 89/214 (41%), Positives = 124/214 (57%), Gaps = 13/214 (6%)
Frame = +2
Query: 110 LHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 289
L+ G +P + LGT + V +AV AI+ GYRHID A VYQ+E +VG I
Sbjct: 7 LNNGAKMPILGLGTWKSPP------GQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQ 60
Query: 290 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP-- 463
E + +V REELF+ +KLW H + V A Q++L L LDY+DLYLIH+P KP
Sbjct: 61 EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK 120
Query: 464 -----DDS----PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI--RP 610
D+S P + + L+TW M++ GL ++IG+SNFN Q+ +++ + +P
Sbjct: 121 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP 180
Query: 611 VINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+NQIE +P TQE L +C S GI V AYSP G
Sbjct: 181 AVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLG 214
>M34720-1|AAA35560.1| 316|Homo sapiens protein ( Human aldose
reductase mRNA, complete cds. ).
Length = 316
Score = 157 bits (382), Expect = 3e-38
Identities = 89/214 (41%), Positives = 124/214 (57%), Gaps = 13/214 (6%)
Frame = +2
Query: 110 LHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 289
L+ G +P + LGT + V +AV AI+ GYRHID A VYQ+E +VG I
Sbjct: 7 LNNGAKMPILGLGTWKSPP------GQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQ 60
Query: 290 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP-- 463
E + +V REELF+ +KLW H + V A Q++L L LDY+DLYLIH+P KP
Sbjct: 61 EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK 120
Query: 464 -----DDS----PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI--RP 610
D+S P + + L+TW M++ GL ++IG+SNFN Q+ +++ + +P
Sbjct: 121 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP 180
Query: 611 VINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+NQIE +P TQE L +C S GI V AYSP G
Sbjct: 181 AVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLG 214
>M33375-1|AAA35658.1| 308|Homo sapiens protein ( Human chlordecone
reductase mRNA, complete cds. ).
Length = 308
Score = 157 bits (382), Expect = 3e-38
Identities = 82/180 (45%), Positives = 112/180 (62%), Gaps = 13/180 (7%)
Frame = +2
Query: 212 AIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQ 391
AIEAG+RHID+A +Y +EEQVG I IA+G V RE++F T+KLW V PAL+
Sbjct: 26 AIEAGFRHIDSAYLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALE 85
Query: 392 ESLKKLGLDYIDLYLIHFPIATKPDDSP-----------DNIDYLETWQGMQDARQLGLA 538
SLKKL LDY+DLYL+HFP+A KP ++P D +D TW+ M+ + GLA
Sbjct: 86 SSLKKLQLDYVDLYLLHFPMALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLA 145
Query: 539 RSIGVSNFNATQITRLVSNSYI--RPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+SIGVSNFN Q+ +++ + +PV NQ+E +P Q L C S I ++A+S G
Sbjct: 146 KSIGVSNFNCRQLEMILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALG 205
>L43839-1|AAB41916.1| 323|Homo sapiens 3-alpha-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 157 bits (382), Expect = 3e-38
Identities = 89/217 (41%), Positives = 126/217 (58%), Gaps = 13/217 (5%)
Frame = +2
Query: 101 CIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQ 280
C++L+ G +P + GT V + AIEAG+RHID+A +Y +EEQVG
Sbjct: 7 CVKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKL---AIEAGFRHIDSAHLYNNEEQVGL 63
Query: 281 GIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATK 460
I IA+G V RE++F T+KLW+ H + V PAL+ SLKK LDY+DLYLIH P++ K
Sbjct: 64 AIRSKIADGSVMREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLK 123
Query: 461 PDD--SP---------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI- 604
P + SP D +D TW+ M+ + GLA+SIGVSNFN Q+ +++ +
Sbjct: 124 PGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEIILNKPGLK 183
Query: 605 -RPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+PV NQ+E +P + L C S I ++AYS G
Sbjct: 184 YKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALG 220
>J05474-1|AAA51715.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 157 bits (382), Expect = 3e-38
Identities = 89/214 (41%), Positives = 124/214 (57%), Gaps = 13/214 (6%)
Frame = +2
Query: 110 LHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 289
L+ G +P + LGT + V +AV AI+ GYRHID A VYQ+E +VG I
Sbjct: 7 LNNGAKMPILGLGTWKSPP------GQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQ 60
Query: 290 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP-- 463
E + +V REELF+ +KLW H + V A Q++L L LDY+DLYLIH+P KP
Sbjct: 61 EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK 120
Query: 464 -----DDS----PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI--RP 610
D+S P + + L+TW M++ GL ++IG+SNFN Q+ +++ + +P
Sbjct: 121 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP 180
Query: 611 VINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+NQIE +P TQE L +C S GI V AYSP G
Sbjct: 181 AVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLG 214
>J04795-1|AAA51713.1| 316|Homo sapiens ALDR1 protein.
Length = 316
Score = 157 bits (382), Expect = 3e-38
Identities = 89/214 (41%), Positives = 124/214 (57%), Gaps = 13/214 (6%)
Frame = +2
Query: 110 LHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 289
L+ G +P + LGT + V +AV AI+ GYRHID A VYQ+E +VG I
Sbjct: 7 LNNGAKMPILGLGTWKSPP------GQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQ 60
Query: 290 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP-- 463
E + +V REELF+ +KLW H + V A Q++L L LDY+DLYLIH+P KP
Sbjct: 61 EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK 120
Query: 464 -----DDS----PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI--RP 610
D+S P + + L+TW M++ GL ++IG+SNFN Q+ +++ + +P
Sbjct: 121 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP 180
Query: 611 VINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+NQIE +P TQE L +C S GI V AYSP G
Sbjct: 181 AVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLG 214
>CR450351-1|CAG29347.1| 316|Homo sapiens AKR1B1 protein.
Length = 316
Score = 157 bits (382), Expect = 3e-38
Identities = 89/214 (41%), Positives = 124/214 (57%), Gaps = 13/214 (6%)
Frame = +2
Query: 110 LHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 289
L+ G +P + LGT + V +AV AI+ GYRHID A VYQ+E +VG I
Sbjct: 7 LNNGAKMPILGLGTWKSPP------GQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQ 60
Query: 290 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP-- 463
E + +V REELF+ +KLW H + V A Q++L L LDY+DLYLIH+P +P
Sbjct: 61 EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFRPGK 120
Query: 464 -----DDS----PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI--RP 610
D+S P + + L+TW M++ GL ++IG+SNFN Q+ ++S + +P
Sbjct: 121 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILSKPGLKYKP 180
Query: 611 VINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+NQIE +P TQE L +C S GI V AYSP G
Sbjct: 181 AVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLG 214
>BT019859-1|AAV38662.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 157 bits (382), Expect = 3e-38
Identities = 89/214 (41%), Positives = 124/214 (57%), Gaps = 13/214 (6%)
Frame = +2
Query: 110 LHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 289
L+ G +P + LGT + V +AV AI+ GYRHID A VYQ+E +VG I
Sbjct: 7 LNNGAKMPILGLGTWKSPP------GQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQ 60
Query: 290 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP-- 463
E + +V REELF+ +KLW H + V A Q++L L LDY+DLYLIH+P KP
Sbjct: 61 EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK 120
Query: 464 -----DDS----PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI--RP 610
D+S P + + L+TW M++ GL ++IG+SNFN Q+ +++ + +P
Sbjct: 121 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP 180
Query: 611 VINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+NQIE +P TQE L +C S GI V AYSP G
Sbjct: 181 AVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLG 214
>BC010391-1|AAH10391.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 157 bits (382), Expect = 3e-38
Identities = 89/214 (41%), Positives = 124/214 (57%), Gaps = 13/214 (6%)
Frame = +2
Query: 110 LHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 289
L+ G +P + LGT + V +AV AI+ GYRHID A VYQ+E +VG I
Sbjct: 7 LNNGAKMPILGLGTWKSPP------GQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQ 60
Query: 290 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP-- 463
E + +V REELF+ +KLW H + V A Q++L L LDY+DLYLIH+P KP
Sbjct: 61 EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK 120
Query: 464 -----DDS----PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI--RP 610
D+S P + + L+TW M++ GL ++IG+SNFN Q+ +++ + +P
Sbjct: 121 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP 180
Query: 611 VINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+NQIE +P TQE L +C S GI V AYSP G
Sbjct: 181 AVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLG 214
>BC000260-1|AAH00260.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 157 bits (382), Expect = 3e-38
Identities = 89/214 (41%), Positives = 124/214 (57%), Gaps = 13/214 (6%)
Frame = +2
Query: 110 LHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 289
L+ G +P + LGT + V +AV AI+ GYRHID A VYQ+E +VG I
Sbjct: 7 LNNGAKMPILGLGTWKSPP------GQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQ 60
Query: 290 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP-- 463
E + +V REELF+ +KLW H + V A Q++L L LDY+DLYLIH+P KP
Sbjct: 61 EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK 120
Query: 464 -----DDS----PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI--RP 610
D+S P + + L+TW M++ GL ++IG+SNFN Q+ +++ + +P
Sbjct: 121 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP 180
Query: 611 VINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+NQIE +P TQE L +C S GI V AYSP G
Sbjct: 181 AVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLG 214
>AF328729-1|AAN09721.1| 316|Homo sapiens CTCL tumor antigen
HD-CL-07 protein.
Length = 316
Score = 157 bits (382), Expect = 3e-38
Identities = 89/214 (41%), Positives = 124/214 (57%), Gaps = 13/214 (6%)
Frame = +2
Query: 110 LHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 289
L+ G +P + LGT + V +AV AI+ GYRHID A VYQ+E +VG I
Sbjct: 7 LNNGAKMPILGLGTWKSPP------GQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQ 60
Query: 290 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP-- 463
E + +V REELF+ +KLW H + V A Q++L L LDY+DLYLIH+P KP
Sbjct: 61 EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK 120
Query: 464 -----DDS----PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI--RP 610
D+S P + + L+TW M++ GL ++IG+SNFN Q+ +++ + +P
Sbjct: 121 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP 180
Query: 611 VINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+NQIE +P TQE L +C S GI V AYSP G
Sbjct: 181 AVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLG 214
>AF032455-1|AAB88851.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 157 bits (382), Expect = 3e-38
Identities = 89/214 (41%), Positives = 124/214 (57%), Gaps = 13/214 (6%)
Frame = +2
Query: 110 LHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 289
L+ G +P + LGT + V +AV AI+ GYRHID A VYQ+E +VG I
Sbjct: 7 LNNGAKMPILGLGTWKSPP------GQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQ 60
Query: 290 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP-- 463
E + +V REELF+ +KLW H + V A Q++L L LDY+DLYLIH+P KP
Sbjct: 61 EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK 120
Query: 464 -----DDS----PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI--RP 610
D+S P + + L+TW M++ GL ++IG+SNFN Q+ +++ + +P
Sbjct: 121 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP 180
Query: 611 VINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+NQIE +P TQE L +C S GI V AYSP G
Sbjct: 181 AVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLG 214
>AB209796-1|BAD93033.1| 260|Homo sapiens aldo-keto reductase family
1, member B1 variant protein.
Length = 260
Score = 157 bits (382), Expect = 3e-38
Identities = 89/214 (41%), Positives = 124/214 (57%), Gaps = 13/214 (6%)
Frame = +2
Query: 110 LHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 289
L+ G +P + LGT + V +AV AI+ GYRHID A VYQ+E +VG I
Sbjct: 4 LNNGAKMPILGLGTWKSPP------GQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQ 57
Query: 290 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP-- 463
E + +V REELF+ +KLW H + V A Q++L L LDY+DLYLIH+P KP
Sbjct: 58 EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK 117
Query: 464 -----DDS----PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI--RP 610
D+S P + + L+TW M++ GL ++IG+SNFN Q+ +++ + +P
Sbjct: 118 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP 177
Query: 611 VINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+NQIE +P TQE L +C S GI V AYSP G
Sbjct: 178 AVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLG 211
>BC020744-1|AAH20744.1| 323|Homo sapiens aldo-keto reductase family
1, member C4 (chlordecone reductase; 3-alpha hydroxy
protein.
Length = 323
Score = 157 bits (381), Expect = 4e-38
Identities = 88/216 (40%), Positives = 125/216 (57%), Gaps = 13/216 (6%)
Frame = +2
Query: 104 IQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 283
++L+ G +P + GT + V + AIEAG+RHID+A +Y +EEQVG
Sbjct: 8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKL---AIEAGFRHIDSAYLYNNEEQVGLA 64
Query: 284 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 463
I IA+G V RE++F T+KLW V PAL+ SLKKL LDY+DLYL+HFP+A KP
Sbjct: 65 IRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKP 124
Query: 464 DDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI-- 604
++P D +D TW+ M+ + GLA+SIGVSNFN Q+ +++ +
Sbjct: 125 GETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNYRQLEMILNKPGLKY 184
Query: 605 RPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+PV NQ+E +P Q L C S I ++A+S G
Sbjct: 185 KPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALG 220
>BC005387-1|AAH05387.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 152 bits (368), Expect = 1e-36
Identities = 88/214 (41%), Positives = 123/214 (57%), Gaps = 13/214 (6%)
Frame = +2
Query: 110 LHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIA 289
L+ G +P + LGT + V +AV AI+ GYRHID A VYQ+E +VG I
Sbjct: 7 LNNGAKMPILGLGTWKSPP------GQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQ 60
Query: 290 EAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP-- 463
E + +V REELF+ +KLW H + V A Q++L L LDY+DLYLIH+P KP
Sbjct: 61 EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK 120
Query: 464 -----DDS----PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI--RP 610
D+S P + + L+T M++ GL ++IG+SNFN Q+ +++ + +P
Sbjct: 121 EFFPLDESGNVVPSDTNILDTRAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP 180
Query: 611 VINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+NQIE +P TQE L +C S GI V AYSP G
Sbjct: 181 AVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLG 214
>U37100-1|AAC17469.1| 316|Homo sapiens aldose reductase-like
peptide protein.
Length = 316
Score = 151 bits (367), Expect = 2e-36
Identities = 88/219 (40%), Positives = 125/219 (57%), Gaps = 13/219 (5%)
Frame = +2
Query: 95 APCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQV 274
A ++L +P V LGT + + V++AV AI+AGYRHID A VYQ+E +V
Sbjct: 2 ATFVELSTKAKMPIVGLGTWKSP------LGKVKEAVKVAIDAGYRHIDCAYVYQNEHEV 55
Query: 275 GQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA 454
G+ I E I V RE+LF+ +KLW R V A +++LK L L Y+D+YLIH+P
Sbjct: 56 GEAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQG 115
Query: 455 TK------PDDSPDN-----IDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSY 601
K P D N +L+ W+ M++ GL +++GVSNF+ QI +L++
Sbjct: 116 FKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPG 175
Query: 602 I--RPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+ +PV NQ+E +P TQE L +C S GI V AYSP G
Sbjct: 176 LKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLG 214
>CR541801-1|CAG46600.1| 316|Homo sapiens AKR1B10 protein.
Length = 316
Score = 151 bits (367), Expect = 2e-36
Identities = 88/219 (40%), Positives = 125/219 (57%), Gaps = 13/219 (5%)
Frame = +2
Query: 95 APCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQV 274
A ++L +P V LGT + + V++AV AI+AGYRHID A VYQ+E +V
Sbjct: 2 ATFVELSTKAKMPIVGLGTWKSP------LGKVKEAVKVAIDAGYRHIDCAYVYQNEHEV 55
Query: 275 GQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA 454
G+ I E I V RE+LF+ +KLW R V A +++LK L L Y+D+YLIH+P
Sbjct: 56 GEAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQG 115
Query: 455 TK------PDDSPDN-----IDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSY 601
K P D N +L+ W+ M++ GL +++GVSNF+ QI +L++
Sbjct: 116 FKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPG 175
Query: 602 I--RPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+ +PV NQ+E +P TQE L +C S GI V AYSP G
Sbjct: 176 LKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLG 214
>BT006794-1|AAP35440.1| 316|Homo sapiens aldo-keto reductase family
1, member B10 (aldose reductase) protein.
Length = 316
Score = 151 bits (367), Expect = 2e-36
Identities = 88/219 (40%), Positives = 125/219 (57%), Gaps = 13/219 (5%)
Frame = +2
Query: 95 APCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQV 274
A ++L +P V LGT + + V++AV AI+AGYRHID A VYQ+E +V
Sbjct: 2 ATFVELSTKAKMPIVGLGTWKSP------LGKVKEAVKVAIDAGYRHIDCAYVYQNEHEV 55
Query: 275 GQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA 454
G+ I E I V RE+LF+ +KLW R V A +++LK L L Y+D+YLIH+P
Sbjct: 56 GEAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQG 115
Query: 455 TK------PDDSPDN-----IDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSY 601
K P D N +L+ W+ M++ GL +++GVSNF+ QI +L++
Sbjct: 116 FKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPG 175
Query: 602 I--RPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+ +PV NQ+E +P TQE L +C S GI V AYSP G
Sbjct: 176 LKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLG 214
>BC008837-1|AAH08837.1| 316|Homo sapiens aldo-keto reductase family
1, member B10 (aldose reductase) protein.
Length = 316
Score = 151 bits (367), Expect = 2e-36
Identities = 88/219 (40%), Positives = 125/219 (57%), Gaps = 13/219 (5%)
Frame = +2
Query: 95 APCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQV 274
A ++L +P V LGT + + V++AV AI+AGYRHID A VYQ+E +V
Sbjct: 2 ATFVELSTKAKMPIVGLGTWKSP------LGKVKEAVKVAIDAGYRHIDCAYVYQNEHEV 55
Query: 275 GQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA 454
G+ I E I V RE+LF+ +KLW R V A +++LK L L Y+D+YLIH+P
Sbjct: 56 GEAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQG 115
Query: 455 TK------PDDSPDN-----IDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSY 601
K P D N +L+ W+ M++ GL +++GVSNF+ QI +L++
Sbjct: 116 FKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPG 175
Query: 602 I--RPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+ +PV NQ+E +P TQE L +C S GI V AYSP G
Sbjct: 176 LKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLG 214
>AF052577-1|AAC36465.1| 316|Homo sapiens aldo-keto reductase
protein.
Length = 316
Score = 151 bits (367), Expect = 2e-36
Identities = 88/219 (40%), Positives = 125/219 (57%), Gaps = 13/219 (5%)
Frame = +2
Query: 95 APCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQV 274
A ++L +P V LGT + + V++AV AI+AGYRHID A VYQ+E +V
Sbjct: 2 ATFVELSTKAKMPIVGLGTWKSP------LGKVKEAVKVAIDAGYRHIDCAYVYQNEHEV 55
Query: 275 GQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA 454
G+ I E I V RE+LF+ +KLW R V A +++LK L L Y+D+YLIH+P
Sbjct: 56 GEAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQG 115
Query: 455 TK------PDDSPDN-----IDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSY 601
K P D N +L+ W+ M++ GL +++GVSNF+ QI +L++
Sbjct: 116 FKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPG 175
Query: 602 I--RPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+ +PV NQ+E +P TQE L +C S GI V AYSP G
Sbjct: 176 LKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLG 214
>AF524864-1|AAO13380.1| 316|Homo sapiens aldo-ketoreductase
protein.
Length = 316
Score = 149 bits (360), Expect = 1e-35
Identities = 87/219 (39%), Positives = 124/219 (56%), Gaps = 13/219 (5%)
Frame = +2
Query: 95 APCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQV 274
A ++L +P V LGT + + V++AV AI+AGYRHID A VYQ+E +V
Sbjct: 2 ATFVELSTKAKMPIVGLGTWKSP------LGKVKEAVKVAIDAGYRHIDCAYVYQNEHEV 55
Query: 275 GQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIA 454
G+ I E I V RE+LF+ +KLW R V A +++LK L Y+D+YLIH+P
Sbjct: 56 GEAIQEKIQEKAVKREDLFIASKLWPTFFERPLVRKAFEKTLKDPKLSYLDVYLIHWPQG 115
Query: 455 TK------PDDSPDN-----IDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSY 601
K P D N +L+ W+ M++ GL +++GVSNF+ QI +L++
Sbjct: 116 FKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPG 175
Query: 602 I--RPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+ +PV NQ+E +P TQE L +C S GI V AYSP G
Sbjct: 176 LKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLG 214
>Z28339-1|CAA82193.1| 326|Homo sapiens delta 4-3-oxosteroid 5
beta-reductase protein.
Length = 326
Score = 147 bits (356), Expect = 4e-35
Identities = 84/216 (38%), Positives = 118/216 (54%), Gaps = 13/216 (6%)
Frame = +2
Query: 104 IQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 283
I L G +P + LGT + S +V AI+ GYRHID A +YQ+E +VG+
Sbjct: 10 IPLSDGNSIPIIGLGTY--SEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEA 67
Query: 284 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 463
I E IA G V RE++F KLW H + V P L+ +L+ L LDY+DLY+I P+A KP
Sbjct: 68 IREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKP 127
Query: 464 DDS----PDNIDYL-------ETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI-- 604
D +N +L TW+ M+ + GL +S+GVSNFN Q+ +++ +
Sbjct: 128 GDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKH 187
Query: 605 RPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+PV NQ+E +P TQ L C I + AYSP G
Sbjct: 188 KPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLG 223
>BC130627-1|AAI30628.1| 326|Homo sapiens aldo-keto reductase family
1, member D1 (delta 4-3-ketosteroid-5-beta-reductase
protein.
Length = 326
Score = 147 bits (356), Expect = 4e-35
Identities = 84/216 (38%), Positives = 118/216 (54%), Gaps = 13/216 (6%)
Frame = +2
Query: 104 IQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 283
I L G +P + LGT + S +V AI+ GYRHID A +YQ+E +VG+
Sbjct: 10 IPLSDGNSIPIIGLGTY--SEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEA 67
Query: 284 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 463
I E IA G V RE++F KLW H + V P L+ +L+ L LDY+DLY+I P+A KP
Sbjct: 68 IREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKP 127
Query: 464 DDS----PDNIDYL-------ETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI-- 604
D +N +L TW+ M+ + GL +S+GVSNFN Q+ +++ +
Sbjct: 128 GDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKH 187
Query: 605 RPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+PV NQ+E +P TQ L C I + AYSP G
Sbjct: 188 KPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLG 223
>BC130625-1|AAI30626.1| 326|Homo sapiens aldo-keto reductase family
1, member D1 (delta 4-3-ketosteroid-5-beta-reductase
protein.
Length = 326
Score = 147 bits (356), Expect = 4e-35
Identities = 84/216 (38%), Positives = 118/216 (54%), Gaps = 13/216 (6%)
Frame = +2
Query: 104 IQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 283
I L G +P + LGT + S +V AI+ GYRHID A +YQ+E +VG+
Sbjct: 10 IPLSDGNSIPIIGLGTY--SEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEA 67
Query: 284 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 463
I E IA G V RE++F KLW H + V P L+ +L+ L LDY+DLY+I P+A KP
Sbjct: 68 IREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKP 127
Query: 464 DDS----PDNIDYL-------ETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI-- 604
D +N +L TW+ M+ + GL +S+GVSNFN Q+ +++ +
Sbjct: 128 GDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKH 187
Query: 605 RPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+PV NQ+E +P TQ L C I + AYSP G
Sbjct: 188 KPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLG 223
>AF283659-1|AAG39381.1| 326|Homo sapiens 5-beta steroid reductase
protein.
Length = 326
Score = 147 bits (356), Expect = 4e-35
Identities = 84/216 (38%), Positives = 118/216 (54%), Gaps = 13/216 (6%)
Frame = +2
Query: 104 IQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 283
I L G +P + LGT + S +V AI+ GYRHID A +YQ+E +VG+
Sbjct: 10 IPLSDGNSIPIIGLGTY--SEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEA 67
Query: 284 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 463
I E IA G V RE++F KLW H + V P L+ +L+ L LDY+DLY+I P+A KP
Sbjct: 68 IREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKP 127
Query: 464 DDS----PDNIDYL-------ETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI-- 604
D +N +L TW+ M+ + GL +S+GVSNFN Q+ +++ +
Sbjct: 128 GDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKH 187
Query: 605 RPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+PV NQ+E +P TQ L C I + AYSP G
Sbjct: 188 KPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLG 223
>AL713867-3|CAI16410.1| 247|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 247
Score = 129 bits (312), Expect = 9e-30
Identities = 67/161 (41%), Positives = 95/161 (59%), Gaps = 13/161 (8%)
Frame = +2
Query: 269 QVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFP 448
+VG I IA+G V RE++F T+KLW + H + V PAL+ SLK L LDY+DLYLIHFP
Sbjct: 26 EVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFP 85
Query: 449 IATKPDDSP-----------DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSN 595
++ KP + D +D TW+ ++ + GLA+SIGVSNFN Q+ +++
Sbjct: 86 VSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNK 145
Query: 596 SYI--RPVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+ +PV NQ+E +P Q L C S I ++AYS G
Sbjct: 146 PGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALG 186
>AL355480-2|CAI22458.1| 147|Homo sapiens aldo-keto reductase family
1, member A1 (aldehydela) protein.
Length = 147
Score = 118 bits (284), Expect = 2e-26
Identities = 62/151 (41%), Positives = 90/151 (59%), Gaps = 12/151 (7%)
Frame = +2
Query: 95 APCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQV 274
A C+ LH G +P + LGT + V+ AV +A+ GYRHID AA+Y +E ++
Sbjct: 3 ASCVLLHTGQKMPLIGLGTWKSEP------GQVKAAVKYALSVGYRHIDCAAIYGNEPEI 56
Query: 275 GQGIAEAIANG-LVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPI 451
G+ + E + G V REELFVT+KLWN KH + V PAL+++L L L+Y+DLYL+H+P
Sbjct: 57 GEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPY 116
Query: 452 ATKPDDSP-----------DNIDYLETWQGM 511
A + D+P D+ Y ETW+ +
Sbjct: 117 AFERGDNPFPKNADGTICYDSTHYKETWKAL 147
>BC002862-1|AAH02862.1| 307|Homo sapiens AKR1CL2 protein protein.
Length = 307
Score = 110 bits (265), Expect = 4e-24
Identities = 79/217 (36%), Positives = 110/217 (50%), Gaps = 32/217 (14%)
Frame = +2
Query: 158 GTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVT 337
G + S V +AV AI+AGYRH D A Y +E +VG GI I G V RE+LF+
Sbjct: 8 GLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDLFIA 67
Query: 338 TKLWNDKHARDQVVPALQ---ESLKKLGLDY----------------------IDLYLIH 442
TKLW H + V A + ++LK LD + L H
Sbjct: 68 TKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELSFCLSH 127
Query: 443 FPIATKP-DDS----PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR 607
+ P D+S P + D+L+TW+ M+D GL ++IGVSNFN Q+ RL++ +R
Sbjct: 128 PRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLR 187
Query: 608 --PVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
P+ NQIE +P TQ+ L + C S ++V AY P G
Sbjct: 188 FKPLTNQIECHPYLTQKNLISFCQSRDVSVTAYRPLG 224
>AF263242-1|AAK58523.1| 320|Homo sapiens aldo-keto reductase
loopADR protein.
Length = 320
Score = 110 bits (265), Expect = 4e-24
Identities = 79/217 (36%), Positives = 110/217 (50%), Gaps = 32/217 (14%)
Frame = +2
Query: 158 GTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVT 337
G + S V +AV AI+AGYRH D A Y +E +VG GI I G V RE+LF+
Sbjct: 8 GLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDLFIA 67
Query: 338 TKLWNDKHARDQVVPALQ---ESLKKLGLDY----------------------IDLYLIH 442
TKLW H + V A + ++LK LD + L H
Sbjct: 68 TKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELSFCLSH 127
Query: 443 FPIATKP-DDS----PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR 607
+ P D+S P + D+L+TW+ M+D GL ++IGVSNFN Q+ RL++ +R
Sbjct: 128 PRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLR 187
Query: 608 --PVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
P+ NQIE +P TQ+ L + C S ++V AY P G
Sbjct: 188 FKPLTNQIECHPYLTQKNLISFCQSRDVSVTAYRPLG 224
>AB055603-1|BAC54568.1| 307|Homo sapiens aldo-keto reductase
related protein 4 protein.
Length = 307
Score = 110 bits (265), Expect = 4e-24
Identities = 79/217 (36%), Positives = 110/217 (50%), Gaps = 32/217 (14%)
Frame = +2
Query: 158 GTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVT 337
G + S V +AV AI+AGYRH D A Y +E +VG GI I G V RE+LF+
Sbjct: 8 GLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDLFIA 67
Query: 338 TKLWNDKHARDQVVPALQ---ESLKKLGLDY----------------------IDLYLIH 442
TKLW H + V A + ++LK LD + L H
Sbjct: 68 TKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELSFCLSH 127
Query: 443 FPIATKP-DDS----PDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIR 607
+ P D+S P + D+L+TW+ M+D GL ++IGVSNFN Q+ RL++ +R
Sbjct: 128 PRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLR 187
Query: 608 --PVINQIEVNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
P+ NQIE +P TQ+ L + C S ++V AY P G
Sbjct: 188 FKPLTNQIECHPYLTQKNLISFCQSRDVSVTAYRPLG 224
>AL391427-2|CAI14727.1| 302|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 302
Score = 109 bits (263), Expect = 8e-24
Identities = 73/208 (35%), Positives = 107/208 (51%), Gaps = 1/208 (0%)
Frame = +2
Query: 92 QAPCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQ 271
Q+ ++L+ G +P + GT A +A AI+ G+RHID+A +YQ+EE+
Sbjct: 7 QSHSVRLNDGPFMPVLGFGT---YAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEE 63
Query: 272 VGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPI 451
VGQ I E IA+G V REE+F T KLW + V PAL+ SLKKLG DY+DL++IH P
Sbjct: 64 VGQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPF 123
Query: 452 ATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQ-IE 628
A K + L +DA + ++ + + ++ +P NQ +E
Sbjct: 124 AMKQPGK----ELLP-----KDASGEIILETVELCDTWELELILNKPGLRYKPTCNQVVE 174
Query: 629 VNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+P Q L C S I ++AYS G
Sbjct: 175 CHPYLNQSKLLEFCKSKDIVLVAYSALG 202
>AL355303-1|CAI14201.1| 302|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 302
Score = 109 bits (263), Expect = 8e-24
Identities = 73/208 (35%), Positives = 107/208 (51%), Gaps = 1/208 (0%)
Frame = +2
Query: 92 QAPCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQ 271
Q+ ++L+ G +P + GT A +A AI+ G+RHID+A +YQ+EE+
Sbjct: 7 QSHSVRLNDGPFMPVLGFGT---YAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEE 63
Query: 272 VGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPI 451
VGQ I E IA+G V REE+F T KLW + V PAL+ SLKKLG DY+DL++IH P
Sbjct: 64 VGQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPF 123
Query: 452 ATKPDDSPDNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQ-IE 628
A K + L +DA + ++ + + ++ +P NQ +E
Sbjct: 124 AMKQPGK----ELLP-----KDASGEIILETVELCDTWELELILNKPGLRYKPTCNQVVE 174
Query: 629 VNPTNTQEPLXAHCXSLGIAVMAYSPFG 712
+P Q L C S I ++AYS G
Sbjct: 175 CHPYLNQSKLLEFCKSKDIVLVAYSALG 202
>BC101205-1|AAI01206.1| 129|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 129
Score = 105 bits (253), Expect = 1e-22
Identities = 56/123 (45%), Positives = 76/123 (61%)
Frame = +2
Query: 92 QAPCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQ 271
Q+ ++L+ G +P + GT A +A AI+ G+RHID+A +YQ+EE+
Sbjct: 7 QSHSVRLNDGPFMPVLGFGT---YAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEE 63
Query: 272 VGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPI 451
VGQ I E IA+G V REE+F T KLW + V PAL+ SLKKLG DY+DL++IH P
Sbjct: 64 VGQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPF 123
Query: 452 ATK 460
A K
Sbjct: 124 AMK 126
>BC101204-1|AAI01205.1| 129|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 129
Score = 105 bits (253), Expect = 1e-22
Identities = 56/123 (45%), Positives = 76/123 (61%)
Frame = +2
Query: 92 QAPCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQ 271
Q+ ++L+ G +P + GT A +A AI+ G+RHID+A +YQ+EE+
Sbjct: 7 QSHSVRLNDGPFMPVLGFGT---YAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEE 63
Query: 272 VGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPI 451
VGQ I E IA+G V REE+F T KLW + V PAL+ SLKKLG DY+DL++IH P
Sbjct: 64 VGQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPF 123
Query: 452 ATK 460
A K
Sbjct: 124 AMK 126
>AK131335-1|BAD18494.1| 129|Homo sapiens protein ( Homo sapiens
cDNA FLJ16347 fis, clone TESTI2036288, moderately
similar to PROSTAGLANDIN-F SYNTHASE 1 (EC 1.1.1.188). ).
Length = 129
Score = 105 bits (253), Expect = 1e-22
Identities = 56/123 (45%), Positives = 76/123 (61%)
Frame = +2
Query: 92 QAPCIQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQ 271
Q+ ++L+ G +P + GT A +A AI+ G+RHID+A +YQ+EE+
Sbjct: 7 QSHSVRLNDGPFMPVLGFGT---YAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEE 63
Query: 272 VGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPI 451
VGQ I E IA+G V REE+F T KLW + V PAL+ SLKKLG DY+DL++IH P
Sbjct: 64 VGQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPF 123
Query: 452 ATK 460
A K
Sbjct: 124 AMK 126
>AB037902-1|BAA92887.1| 130|Homo sapiens truncated aldo-keto
reductase protein.
Length = 130
Score = 100 bits (239), Expect = 6e-21
Identities = 51/123 (41%), Positives = 75/123 (60%)
Frame = +2
Query: 104 IQLHAGXPLPXVALGTGRGTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 283
++L+ G +P + GT + ++ V +AV AI+ GYRHID+A + +EE +GQ
Sbjct: 9 VKLNDGKFMPILGFGT---SVARKVAMSNVEEAVQVAIDVGYRHIDSAYTHLNEEGIGQA 65
Query: 284 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 463
I + IANG V R+++F TTK+W + V L+ SLKKL L Y+DLYL HFP+ +P
Sbjct: 66 IRKKIANGTVKRKDIFYTTKVWGTFSRPELVQRGLEMSLKKLQLSYMDLYLFHFPVPLQP 125
Query: 464 DDS 472
S
Sbjct: 126 GRS 128
>AB040822-1|BAC54567.1| 222|Homo sapiens aldo-keto reductase
related protein 3 protein.
Length = 222
Score = 96.7 bits (230), Expect = 8e-20
Identities = 49/102 (48%), Positives = 63/102 (61%)
Frame = +2
Query: 158 GTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVT 337
G + S V +AV AI+AGYRH D A Y +E +VG GI I G V RE+LF+
Sbjct: 8 GLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDLFIA 67
Query: 338 TKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 463
TKLW H + V A ++SLK L L+Y+DLYLIH+P+ KP
Sbjct: 68 TKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKP 109
>AB040821-1|BAC54566.1| 263|Homo sapiens aldo-keto reductase
related protein 2 protein.
Length = 263
Score = 96.7 bits (230), Expect = 8e-20
Identities = 49/102 (48%), Positives = 63/102 (61%)
Frame = +2
Query: 158 GTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVT 337
G + S V +AV AI+AGYRH D A Y +E +VG GI I G V RE+LF+
Sbjct: 8 GLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDLFIA 67
Query: 338 TKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 463
TKLW H + V A ++SLK L L+Y+DLYLIH+P+ KP
Sbjct: 68 TKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKP 109
>AB040820-1|BAC54565.1| 250|Homo sapiens aldo-keto reductase
related protein 1 protein.
Length = 250
Score = 96.7 bits (230), Expect = 8e-20
Identities = 49/102 (48%), Positives = 63/102 (61%)
Frame = +2
Query: 158 GTAKXSDSIXXVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTREELFVT 337
G + S V +AV AI+AGYRH D A Y +E +VG GI I G V RE+LF+
Sbjct: 8 GLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDLFIA 67
Query: 338 TKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 463
TKLW H + V A ++SLK L L+Y+DLYLIH+P+ KP
Sbjct: 68 TKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKP 109
>AK058142-1|BAB71682.1| 146|Homo sapiens protein ( Homo sapiens
cDNA FLJ25413 fis, clone TST03402, highly similar to
3-OXO-5-BETA-STEROID 4-DEHYDROGENASE (EC 1.3.99.6). ).
Length = 146
Score = 62.1 bits (144), Expect = 2e-09
Identities = 29/74 (39%), Positives = 43/74 (58%), Gaps = 2/74 (2%)
Frame = +2
Query: 497 TWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI--RPVINQIEVNPTNTQEPLXAHC 670
TW+ M+ + GL +S+GVSNFN Q+ +++ + +PV NQ+E +P TQ L C
Sbjct: 28 TWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKPVSNQVECHPYFTQPKLLKFC 87
Query: 671 XSLGIAVMAYSPFG 712
I + AYSP G
Sbjct: 88 QQHDIVITAYSPLG 101
>Y16675-1|CAA76347.1| 330|Homo sapiens aflatoxin B1-aldehyde
reductase protein.
Length = 330
Score = 51.6 bits (118), Expect = 3e-06
Identities = 48/178 (26%), Positives = 76/178 (42%), Gaps = 9/178 (5%)
Frame = +2
Query: 200 AVYWAIEAGYRHIDTAAVYQD--EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHAR-D 370
AV +E G+ +DTA +Y D E + G+ + G R ++ W+ K + D
Sbjct: 30 AVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGG-DCRVKIATKANPWDGKSLKPD 88
Query: 371 QVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIG 550
V L+ SLK+L +DL+ +H P P + ET Q Q G +G
Sbjct: 89 SVRSQLETSLKRLQCPQVDLFYLHAPDHGTPVE--------ETLHACQRLHQEGKFVELG 140
Query: 551 VSNFNATQITRLV----SNSYIRPVINQIEVNPTNTQ--EPLXAHCXSLGIAVMAYSP 706
+SN+ + ++ + SN +I P + Q N T Q L G+ AY+P
Sbjct: 141 LSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGLRFYAYNP 198
>BT007347-1|AAP36011.1| 330|Homo sapiens aldo-keto reductase family
7, member A2 (aflatoxin aldehyde reductase) protein.
Length = 330
Score = 51.6 bits (118), Expect = 3e-06
Identities = 48/178 (26%), Positives = 76/178 (42%), Gaps = 9/178 (5%)
Frame = +2
Query: 200 AVYWAIEAGYRHIDTAAVYQD--EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHAR-D 370
AV +E G+ +DTA +Y D E + G+ + G R ++ W+ K + D
Sbjct: 30 AVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGG-DCRVKIATKANPWDGKSLKPD 88
Query: 371 QVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIG 550
V L+ SLK+L +DL+ +H P P + ET Q Q G +G
Sbjct: 89 SVRSQLETSLKRLQCPQVDLFYLHAPDHGTPVE--------ETLHACQRLHQEGKFVELG 140
Query: 551 VSNFNATQITRLV----SNSYIRPVINQIEVNPTNTQ--EPLXAHCXSLGIAVMAYSP 706
+SN+ + ++ + SN +I P + Q N T Q L G+ AY+P
Sbjct: 141 LSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGLRFYAYNP 198
>BC013996-1|AAH13996.1| 330|Homo sapiens AKR7A2 protein protein.
Length = 330
Score = 51.6 bits (118), Expect = 3e-06
Identities = 48/178 (26%), Positives = 76/178 (42%), Gaps = 9/178 (5%)
Frame = +2
Query: 200 AVYWAIEAGYRHIDTAAVYQD--EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHAR-D 370
AV +E G+ +DTA +Y D E + G+ + G R ++ W+ K + D
Sbjct: 30 AVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGG-DCRVKIATKANPWDGKSLKPD 88
Query: 371 QVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIG 550
V L+ SLK+L +DL+ +H P P + ET Q Q G +G
Sbjct: 89 SVRSQLETSLKRLQCPQVDLFYLHAPDHGTPVE--------ETLHACQRLHQEGKFVELG 140
Query: 551 VSNFNATQITRLV----SNSYIRPVINQIEVNPTNTQ--EPLXAHCXSLGIAVMAYSP 706
+SN+ + ++ + SN +I P + Q N T Q L G+ AY+P
Sbjct: 141 LSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGLRFYAYNP 198
>BC012171-1|AAH12171.1| 330|Homo sapiens AKR7A2 protein protein.
Length = 330
Score = 51.6 bits (118), Expect = 3e-06
Identities = 48/178 (26%), Positives = 76/178 (42%), Gaps = 9/178 (5%)
Frame = +2
Query: 200 AVYWAIEAGYRHIDTAAVYQD--EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHAR-D 370
AV +E G+ +DTA +Y D E + G+ + G R ++ W+ K + D
Sbjct: 30 AVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGG-DCRVKIATKANPWDGKSLKPD 88
Query: 371 QVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIG 550
V L+ SLK+L +DL+ +H P P + ET Q Q G +G
Sbjct: 89 SVRSQLETSLKRLQCPQVDLFYLHAPDHGTPVE--------ETLHACQRLHQEGKFVELG 140
Query: 551 VSNFNATQITRLV----SNSYIRPVINQIEVNPTNTQ--EPLXAHCXSLGIAVMAYSP 706
+SN+ + ++ + SN +I P + Q N T Q L G+ AY+P
Sbjct: 141 LSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGLRFYAYNP 198
>BC011586-1|AAH11586.1| 330|Homo sapiens AKR7A2 protein protein.
Length = 330
Score = 51.6 bits (118), Expect = 3e-06
Identities = 48/178 (26%), Positives = 76/178 (42%), Gaps = 9/178 (5%)
Frame = +2
Query: 200 AVYWAIEAGYRHIDTAAVYQD--EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHAR-D 370
AV +E G+ +DTA +Y D E + G+ + G R ++ W+ K + D
Sbjct: 30 AVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGG-DCRVKIATKANPWDGKSLKPD 88
Query: 371 QVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIG 550
V L+ SLK+L +DL+ +H P P + ET Q Q G +G
Sbjct: 89 SVRSQLETSLKRLQCPQVDLFYLHAPDHGTPVE--------ETLHACQRLHQEGKFVELG 140
Query: 551 VSNFNATQITRLV----SNSYIRPVINQIEVNPTNTQ--EPLXAHCXSLGIAVMAYSP 706
+SN+ + ++ + SN +I P + Q N T Q L G+ AY+P
Sbjct: 141 LSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGLRFYAYNP 198
>BC010852-1|AAH10852.1| 330|Homo sapiens AKR7A2 protein protein.
Length = 330
Score = 51.6 bits (118), Expect = 3e-06
Identities = 48/178 (26%), Positives = 76/178 (42%), Gaps = 9/178 (5%)
Frame = +2
Query: 200 AVYWAIEAGYRHIDTAAVYQD--EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHAR-D 370
AV +E G+ +DTA +Y D E + G+ + G R ++ W+ K + D
Sbjct: 30 AVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGG-DCRVKIATKANPWDGKSLKPD 88
Query: 371 QVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIG 550
V L+ SLK+L +DL+ +H P P + ET Q Q G +G
Sbjct: 89 SVRSQLETSLKRLQCPQVDLFYLHAPDHGTPVE--------ETLHACQRLHQEGKFVELG 140
Query: 551 VSNFNATQITRLV----SNSYIRPVINQIEVNPTNTQ--EPLXAHCXSLGIAVMAYSP 706
+SN+ + ++ + SN +I P + Q N T Q L G+ AY+P
Sbjct: 141 LSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGLRFYAYNP 198
>BC007352-1|AAH07352.2| 358|Homo sapiens AKR7A2 protein protein.
Length = 358
Score = 51.6 bits (118), Expect = 3e-06
Identities = 48/178 (26%), Positives = 76/178 (42%), Gaps = 9/178 (5%)
Frame = +2
Query: 200 AVYWAIEAGYRHIDTAAVYQD--EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHAR-D 370
AV +E G+ +DTA +Y D E + G+ + G R ++ W+ K + D
Sbjct: 58 AVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGG-DCRVKIATKANPWDGKSLKPD 116
Query: 371 QVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIG 550
V L+ SLK+L +DL+ +H P P + ET Q Q G +G
Sbjct: 117 SVRSQLETSLKRLQCPQVDLFYLHAPDHGTPVE--------ETLHACQRLHQEGKFVELG 168
Query: 551 VSNFNATQITRLV----SNSYIRPVINQIEVNPTNTQ--EPLXAHCXSLGIAVMAYSP 706
+SN+ + ++ + SN +I P + Q N T Q L G+ AY+P
Sbjct: 169 LSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGLRFYAYNP 226
>BC004111-1|AAH04111.3| 330|Homo sapiens AKR7A2 protein protein.
Length = 330
Score = 51.6 bits (118), Expect = 3e-06
Identities = 48/178 (26%), Positives = 76/178 (42%), Gaps = 9/178 (5%)
Frame = +2
Query: 200 AVYWAIEAGYRHIDTAAVYQD--EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHAR-D 370
AV +E G+ +DTA +Y D E + G+ + G R ++ W+ K + D
Sbjct: 30 AVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGG-DCRVKIATKANPWDGKSLKPD 88
Query: 371 QVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIG 550
V L+ SLK+L +DL+ +H P P + ET Q Q G +G
Sbjct: 89 SVRSQLETSLKRLQCPQVDLFYLHAPDHGTPVE--------ETLHACQRLHQEGKFVELG 140
Query: 551 VSNFNATQITRLV----SNSYIRPVINQIEVNPTNTQ--EPLXAHCXSLGIAVMAYSP 706
+SN+ + ++ + SN +I P + Q N T Q L G+ AY+P
Sbjct: 141 LSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGLRFYAYNP 198
>AL035413-8|CAB72321.1| 330|Homo sapiens aldo-keto reductase family
7, member A2 (aflatoxin aldehyde reductase) protein.
Length = 330
Score = 51.6 bits (118), Expect = 3e-06
Identities = 48/178 (26%), Positives = 76/178 (42%), Gaps = 9/178 (5%)
Frame = +2
Query: 200 AVYWAIEAGYRHIDTAAVYQD--EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHAR-D 370
AV +E G+ +DTA +Y D E + G+ + G R ++ W+ K + D
Sbjct: 30 AVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGG-DCRVKIATKANPWDGKSLKPD 88
Query: 371 QVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIG 550
V L+ SLK+L +DL+ +H P P + ET Q Q G +G
Sbjct: 89 SVRSQLETSLKRLQCPQVDLFYLHAPDHGTPVE--------ETLHACQRLHQEGKFVELG 140
Query: 551 VSNFNATQITRLV----SNSYIRPVINQIEVNPTNTQ--EPLXAHCXSLGIAVMAYSP 706
+SN+ + ++ + SN +I P + Q N T Q L G+ AY+P
Sbjct: 141 LSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGLRFYAYNP 198
>AF026947-1|AAC52104.1| 330|Homo sapiens aflatoxin aldehyde
reductase AFAR protein.
Length = 330
Score = 51.6 bits (118), Expect = 3e-06
Identities = 48/178 (26%), Positives = 76/178 (42%), Gaps = 9/178 (5%)
Frame = +2
Query: 200 AVYWAIEAGYRHIDTAAVYQD--EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHAR-D 370
AV +E G+ +DTA +Y D E + G+ + G R ++ W+ K + D
Sbjct: 30 AVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGG-DCRVKIATKANPWDGKSLKPD 88
Query: 371 QVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIG 550
V L+ SLK+L +DL+ +H P P + ET Q Q G +G
Sbjct: 89 SVRSQLETSLKRLQCPQVDLFYLHTPDHGTPVE--------ETLHACQRLHQEGKFVELG 140
Query: 551 VSNFNATQITRLV----SNSYIRPVINQIEVNPTNTQ--EPLXAHCXSLGIAVMAYSP 706
+SN+ + ++ + SN +I P + Q N T Q L G+ AY+P
Sbjct: 141 LSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGLRFYAYNP 198
>AB028065-1|BAA88489.1| 67|Homo sapiens prostaglandin F synthase
protein.
Length = 67
Score = 46.4 bits (105), Expect = 1e-04
Identities = 21/51 (41%), Positives = 32/51 (62%), Gaps = 2/51 (3%)
Frame = +2
Query: 476 DNIDYLETWQGMQDARQLGLARSIGVSNFNATQITRLVSNSYI--RPVINQ 622
D +D TW+ M+ + GLA+SIGVSNFN Q+ +++ + +PV NQ
Sbjct: 17 DIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQ 67
>AF040639-1|AAD02195.1| 331|Homo sapiens aflatoxin B1-aldehyde
reductase protein.
Length = 331
Score = 43.2 bits (97), Expect = 0.001
Identities = 48/178 (26%), Positives = 75/178 (42%), Gaps = 14/178 (7%)
Frame = +2
Query: 215 IEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTRE-----ELFVTTK---LWNDKHARD 370
+E G+ IDTA VY D G +E I GL R + + TK L+ + D
Sbjct: 36 LERGHTEIDTAFVYSD------GQSETILGGLGLRLGGSDCRVKIDTKAIPLFGNSLKPD 89
Query: 371 QVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIG 550
+ L+ SLK+L +DL+ +H P + P + ET + Q G +G
Sbjct: 90 SLRFQLETSLKRLQCPRVDLFYLHMPDHSTPVE--------ETLRACHQLHQEGKFMELG 141
Query: 551 VSNFNATQITRLV----SNSYIRPVINQIEVNPTNTQ--EPLXAHCXSLGIAVMAYSP 706
+SN+ A ++ + SN +I P + Q N Q L G+ A++P
Sbjct: 142 LSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVETELFPCLRHFGLRFYAFNP 199
>BC042420-1|AAH42420.2| 331|Homo sapiens aldo-keto reductase family
7, member A3 (aflatoxin aldehyde reductase) protein.
Length = 331
Score = 41.5 bits (93), Expect = 0.003
Identities = 47/178 (26%), Positives = 75/178 (42%), Gaps = 14/178 (7%)
Frame = +2
Query: 215 IEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTRE-----ELFVTTK---LWNDKHARD 370
+E G+ IDTA VY + G +E I GL R + + TK L+ + D
Sbjct: 36 LERGHTEIDTAFVYSE------GQSETILGGLGLRLGGSDCRVKIDTKAIPLFGNSLKPD 89
Query: 371 QVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIG 550
+ L+ SLK+L +DL+ +H P + P + ET + Q G +G
Sbjct: 90 SLRFQLETSLKRLQCPRVDLFYLHMPDHSTPVE--------ETLRACHQLHQEGKFMELG 141
Query: 551 VSNFNATQITRLV----SNSYIRPVINQIEVNPTNTQ--EPLXAHCXSLGIAVMAYSP 706
+SN+ A ++ + SN +I P + Q N Q L G+ A++P
Sbjct: 142 LSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVETELFPCLRHFGLRFYAFNP 199
>BC031562-1|AAH31562.1| 331|Homo sapiens aldo-keto reductase family
7, member A3 (aflatoxin aldehyde reductase) protein.
Length = 331
Score = 41.5 bits (93), Expect = 0.003
Identities = 47/178 (26%), Positives = 75/178 (42%), Gaps = 14/178 (7%)
Frame = +2
Query: 215 IEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTRE-----ELFVTTK---LWNDKHARD 370
+E G+ IDTA VY + G +E I GL R + + TK L+ + D
Sbjct: 36 LERGHTEIDTAFVYSE------GQSETILGGLGLRLGGSDCRVKIDTKAIPLFGNSLKPD 89
Query: 371 QVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIG 550
+ L+ SLK+L +DL+ +H P + P + ET + Q G +G
Sbjct: 90 SLRFQLETSLKRLQCPRVDLFYLHMPDHSTPVE--------ETLRACHQLHQEGKFMELG 141
Query: 551 VSNFNATQITRLV----SNSYIRPVINQIEVNPTNTQ--EPLXAHCXSLGIAVMAYSP 706
+SN+ A ++ + SN +I P + Q N Q L G+ A++P
Sbjct: 142 LSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVETELFPCLRHFGLRFYAFNP 199
>AJ271799-1|CAC81076.1| 331|Homo sapiens aflatoxin B1 aldehyde
reductase 2 protein.
Length = 331
Score = 41.5 bits (93), Expect = 0.003
Identities = 47/178 (26%), Positives = 75/178 (42%), Gaps = 14/178 (7%)
Frame = +2
Query: 215 IEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTRE-----ELFVTTK---LWNDKHARD 370
+E G+ IDTA VY + G +E I GL R + + TK L+ + D
Sbjct: 36 LERGHTEIDTAFVYSE------GQSETILGGLGLRLGGSDCRVKIDTKAIPLFGNSLKPD 89
Query: 371 QVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIG 550
+ L+ SLK+L +DL+ +H P + P + ET + Q G +G
Sbjct: 90 SLRFQLETSLKRLQCPRVDLFYLHMPDHSTPVE--------ETLRACHQLHQEGKFMELG 141
Query: 551 VSNFNATQITRLV----SNSYIRPVINQIEVNPTNTQ--EPLXAHCXSLGIAVMAYSP 706
+SN+ A ++ + SN +I P + Q N Q L G+ A++P
Sbjct: 142 LSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVETELFPCLRHFGLRFYAFNP 199
>AB037905-2|BAA92890.1| 45|Homo sapiens truncated aldo-keto
reductase protein.
Length = 45
Score = 41.1 bits (92), Expect = 0.004
Identities = 19/43 (44%), Positives = 25/43 (58%)
Frame = +2
Query: 344 LWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDS 472
+W + V L+ SLKKL L Y+DLYL HFP+ +P S
Sbjct: 1 VWGTFSRPELVQRGLEMSLKKLQLSYMDLYLFHFPVPLQPGRS 43
>BC025709-1|AAH25709.1| 331|Homo sapiens aldo-keto reductase family
7, member A3 (aflatoxin aldehyde reductase) protein.
Length = 331
Score = 40.7 bits (91), Expect = 0.005
Identities = 47/178 (26%), Positives = 75/178 (42%), Gaps = 14/178 (7%)
Frame = +2
Query: 215 IEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTRE-----ELFVTTK---LWNDKHARD 370
+E G+ IDTA VY + G +E I GL R + + TK L+ + D
Sbjct: 36 LERGHTEIDTAFVYSE------GQSETILGGLGLRLGGSDCRVKIDTKAIPLFGNSLKPD 89
Query: 371 QVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIG 550
+ L+ SLK+L +DL+ +H P + P + ET + Q G +G
Sbjct: 90 SLRFQLETSLKRLQCPRVDLFYLHMPDHSTPVE--------ETLRACHQLHQEGKFVELG 141
Query: 551 VSNFNATQITRLV----SNSYIRPVINQIEVNPTNTQ--EPLXAHCXSLGIAVMAYSP 706
+SN+ A ++ + SN +I P + Q N Q L G+ A++P
Sbjct: 142 LSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVETELFPCLRHFGLRFYAFNP 199
>AL035413-11|CAI22232.1| 331|Homo sapiens aldo-keto reductase
family 7, member A3 (aflatoxin aldehyde reductase)
protein.
Length = 331
Score = 40.7 bits (91), Expect = 0.005
Identities = 47/178 (26%), Positives = 75/178 (42%), Gaps = 14/178 (7%)
Frame = +2
Query: 215 IEAGYRHIDTAAVYQDEEQVGQGIAEAIANGLVTRE-----ELFVTTK---LWNDKHARD 370
+E G+ IDTA VY + G +E I GL R + + TK L+ + D
Sbjct: 36 LERGHTEIDTAFVYSE------GQSETILGGLGLRLGGSDCRVKIDTKAIPLFGNSLKPD 89
Query: 371 QVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSIG 550
+ L+ SLK+L +DL+ +H P + P + ET + Q G +G
Sbjct: 90 SLRFQLETSLKRLQCPRVDLFYLHMPDHSTPVE--------ETLRACHQLHQEGKFVELG 141
Query: 551 VSNFNATQITRLV----SNSYIRPVINQIEVNPTNTQ--EPLXAHCXSLGIAVMAYSP 706
+SN+ A ++ + SN +I P + Q N Q L G+ A++P
Sbjct: 142 LSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVETELFPCLRHFGLRFYAFNP 199
>AJ278012-1|CAC79668.1| 259|Homo sapiens aflatoxin B1 aldehyde
reductase 3 protein.
Length = 259
Score = 39.5 bits (88), Expect = 0.012
Identities = 32/119 (26%), Positives = 52/119 (43%), Gaps = 6/119 (5%)
Frame = +2
Query: 368 DQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYLETWQGMQDARQLGLARSI 547
D V L+ SLK+L +DL+ +H P + P + ET + Q G +
Sbjct: 17 DSVRSQLETSLKRLQCPUVDLFYLHAPDHSAPVE--------ETLRACHQLHQEGKFVEL 68
Query: 548 GVSNFNATQITRLV----SNSYIRPVINQIEVNPTNTQ--EPLXAHCXSLGIAVMAYSP 706
G+SN+ A ++ + SN +I P + Q + T Q L + G+ AY+P
Sbjct: 69 GLSNYAAWEVAEICTLCKSNGWILPTVYQGMYSATTRQVETELFPYLRHFGLRFYAYNP 127
>L35546-1|AAA65028.1| 274|Homo sapiens gamma-glutamylcysteine
synthetase light subunit protein.
Length = 274
Score = 34.3 bits (75), Expect = 0.46
Identities = 29/132 (21%), Positives = 63/132 (47%), Gaps = 3/132 (2%)
Frame = +2
Query: 317 REELFVTTKLWN-DKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYL 493
REE+ V+ KL+ + ++ A+ + LG+ +D +I P D ++++L
Sbjct: 86 REEMKVSAKLFIVESNSSSSTRSAVDMACSVLGVAQLDSVIIASPPIE--DGVNLSLEHL 143
Query: 494 ET-WQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEP-LXAH 667
+ W+ +++ Q +IG S+ + TQ+ +L + ++P NQ+ + P L A
Sbjct: 144 QPYWEELENLVQSKKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQVNLASCCVMPPDLTAF 203
Query: 668 CXSLGIAVMAYS 703
I ++ ++
Sbjct: 204 AKQFDIQLLTHN 215
>CR541833-1|CAG46632.1| 274|Homo sapiens GCLM protein.
Length = 274
Score = 34.3 bits (75), Expect = 0.46
Identities = 29/132 (21%), Positives = 63/132 (47%), Gaps = 3/132 (2%)
Frame = +2
Query: 317 REELFVTTKLWN-DKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYL 493
REE+ V+ KL+ + ++ A+ + LG+ +D +I P D ++++L
Sbjct: 86 REEMKVSAKLFIVESNSSSSTRSAVDMACSVLGVAQLDSVIIASPPIE--DGVNLSLEHL 143
Query: 494 ET-WQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEP-LXAH 667
+ W+ +++ Q +IG S+ + TQ+ +L + ++P NQ+ + P L A
Sbjct: 144 QPYWEELENLVQSKKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQVNLASCCVMPPDLTAF 203
Query: 668 CXSLGIAVMAYS 703
I ++ ++
Sbjct: 204 AKQFDIQLLTHN 215
>BC041809-1|AAH41809.1| 274|Homo sapiens glutamate-cysteine ligase,
modifier subunit protein.
Length = 274
Score = 34.3 bits (75), Expect = 0.46
Identities = 29/132 (21%), Positives = 63/132 (47%), Gaps = 3/132 (2%)
Frame = +2
Query: 317 REELFVTTKLWN-DKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYL 493
REE+ V+ KL+ + ++ A+ + LG+ +D +I P D ++++L
Sbjct: 86 REEMKVSAKLFIVESNSSSSTRSAVDMACSVLGVAQLDSVIIASPPIE--DGVNLSLEHL 143
Query: 494 ET-WQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEP-LXAH 667
+ W+ +++ Q +IG S+ + TQ+ +L + ++P NQ+ + P L A
Sbjct: 144 QPYWEELENLVQSKKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQVNLASCCVMPPDLTAF 203
Query: 668 CXSLGIAVMAYS 703
I ++ ++
Sbjct: 204 AKQFDIQLLTHN 215
>AY773965-1|AAV28733.1| 274|Homo sapiens glutamate-cysteine ligase,
modifier subunit protein.
Length = 274
Score = 34.3 bits (75), Expect = 0.46
Identities = 29/132 (21%), Positives = 63/132 (47%), Gaps = 3/132 (2%)
Frame = +2
Query: 317 REELFVTTKLWN-DKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYL 493
REE+ V+ KL+ + ++ A+ + LG+ +D +I P D ++++L
Sbjct: 86 REEMKVSAKLFIVESNSSSSTRSAVDMACSVLGVAQLDSVIIASPPIE--DGVNLSLEHL 143
Query: 494 ET-WQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEP-LXAH 667
+ W+ +++ Q +IG S+ + TQ+ +L + ++P NQ+ + P L A
Sbjct: 144 QPYWEELENLVQSKKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQVNLASCCVMPPDLTAF 203
Query: 668 CXSLGIAVMAYS 703
I ++ ++
Sbjct: 204 AKQFDIQLLTHN 215
>AL117351-10|CAI22976.1| 274|Homo sapiens glutamate-cysteine
ligase, modifier subunit protein.
Length = 274
Score = 34.3 bits (75), Expect = 0.46
Identities = 29/132 (21%), Positives = 63/132 (47%), Gaps = 3/132 (2%)
Frame = +2
Query: 317 REELFVTTKLWN-DKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYL 493
REE+ V+ KL+ + ++ A+ + LG+ +D +I P D ++++L
Sbjct: 86 REEMKVSAKLFIVESNSSSSTRSAVDMACSVLGVAQLDSVIIASPPIE--DGVNLSLEHL 143
Query: 494 ET-WQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEP-LXAH 667
+ W+ +++ Q +IG S+ + TQ+ +L + ++P NQ+ + P L A
Sbjct: 144 QPYWEELENLVQSKKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQVNLASCCVMPPDLTAF 203
Query: 668 CXSLGIAVMAYS 703
I ++ ++
Sbjct: 204 AKQFDIQLLTHN 215
>AL049796-2|CAI21813.1| 274|Homo sapiens glutamate-cysteine ligase,
modifier subunit protein.
Length = 274
Score = 34.3 bits (75), Expect = 0.46
Identities = 29/132 (21%), Positives = 63/132 (47%), Gaps = 3/132 (2%)
Frame = +2
Query: 317 REELFVTTKLWN-DKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKPDDSPDNIDYL 493
REE+ V+ KL+ + ++ A+ + LG+ +D +I P D ++++L
Sbjct: 86 REEMKVSAKLFIVESNSSSSTRSAVDMACSVLGVAQLDSVIIASPPIE--DGVNLSLEHL 143
Query: 494 ET-WQGMQDARQLGLARSIGVSNFNATQITRLVSNSYIRPVINQIEVNPTNTQEP-LXAH 667
+ W+ +++ Q +IG S+ + TQ+ +L + ++P NQ+ + P L A
Sbjct: 144 QPYWEELENLVQSKKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQVNLASCCVMPPDLTAF 203
Query: 668 CXSLGIAVMAYS 703
I ++ ++
Sbjct: 204 AKQFDIQLLTHN 215
>BC117495-1|AAI17496.1| 905|Homo sapiens stonin 2 protein.
Length = 905
Score = 29.9 bits (64), Expect = 10.0
Identities = 23/79 (29%), Positives = 38/79 (48%), Gaps = 2/79 (2%)
Frame = +2
Query: 245 AAVYQDEEQVGQGIAEAIANGLVTREELFVTTK--LWNDKHARDQVVPALQESLKKLGLD 418
+A ++++E+ Q + + G R+ L V + + D ++ Q E LK+L +D
Sbjct: 332 SAFFEEQERRSQNSSISSTTGKSQRDSLIVIYQDAISFDDSSKTQSHSDAVEKLKQLQID 391
Query: 419 YIDLYLIHFPIATKPDDSP 475
D HF AT PDD P
Sbjct: 392 DPD----HFGSATLPDDDP 406
>BC117493-1|AAI17494.1| 905|Homo sapiens stonin 2 protein.
Length = 905
Score = 29.9 bits (64), Expect = 10.0
Identities = 23/79 (29%), Positives = 38/79 (48%), Gaps = 2/79 (2%)
Frame = +2
Query: 245 AAVYQDEEQVGQGIAEAIANGLVTREELFVTTK--LWNDKHARDQVVPALQESLKKLGLD 418
+A ++++E+ Q + + G R+ L V + + D ++ Q E LK+L +D
Sbjct: 332 SAFFEEQERRSQNSSISSTTGKSQRDSLIVIYQDAISFDDSSKTQSHSDAVEKLKQLQID 391
Query: 419 YIDLYLIHFPIATKPDDSP 475
D HF AT PDD P
Sbjct: 392 DPD----HFGSATLPDDDP 406
>BC069587-1|AAH69587.1| 904|Homo sapiens STON2 protein protein.
Length = 904
Score = 29.9 bits (64), Expect = 10.0
Identities = 23/79 (29%), Positives = 38/79 (48%), Gaps = 2/79 (2%)
Frame = +2
Query: 245 AAVYQDEEQVGQGIAEAIANGLVTREELFVTTK--LWNDKHARDQVVPALQESLKKLGLD 418
+A ++++E+ Q + + G R+ L V + + D ++ Q E LK+L +D
Sbjct: 332 SAFFEEQERRSQNSSISSTTGKSQRDSLIVIYQDAISFDDSSKTQSHSDAVEKLKQLQID 391
Query: 419 YIDLYLIHFPIATKPDDSP 475
D HF AT PDD P
Sbjct: 392 DPD----HFGSATLPDDDP 406
>BC069502-1|AAH69502.1| 905|Homo sapiens stonin 2 protein.
Length = 905
Score = 29.9 bits (64), Expect = 10.0
Identities = 23/79 (29%), Positives = 38/79 (48%), Gaps = 2/79 (2%)
Frame = +2
Query: 245 AAVYQDEEQVGQGIAEAIANGLVTREELFVTTK--LWNDKHARDQVVPALQESLKKLGLD 418
+A ++++E+ Q + + G R+ L V + + D ++ Q E LK+L +D
Sbjct: 332 SAFFEEQERRSQNSSISSTTGKSQRDSLIVIYQDAISFDDSSKTQSHSDAVEKLKQLQID 391
Query: 419 YIDLYLIHFPIATKPDDSP 475
D HF AT PDD P
Sbjct: 392 DPD----HFGSATLPDDDP 406
>BC069389-1|AAH69389.1| 905|Homo sapiens stonin 2 protein.
Length = 905
Score = 29.9 bits (64), Expect = 10.0
Identities = 23/79 (29%), Positives = 38/79 (48%), Gaps = 2/79 (2%)
Frame = +2
Query: 245 AAVYQDEEQVGQGIAEAIANGLVTREELFVTTK--LWNDKHARDQVVPALQESLKKLGLD 418
+A ++++E+ Q + + G R+ L V + + D ++ Q E LK+L +D
Sbjct: 332 SAFFEEQERRSQNSSISSTTGKSQRDSLIVIYQDAISFDDSSKTQSHSDAVEKLKQLQID 391
Query: 419 YIDLYLIHFPIATKPDDSP 475
D HF AT PDD P
Sbjct: 392 DPD----HFGSATLPDDDP 406
>BC069359-1|AAH69359.1| 905|Homo sapiens stonin 2 protein.
Length = 905
Score = 29.9 bits (64), Expect = 10.0
Identities = 23/79 (29%), Positives = 38/79 (48%), Gaps = 2/79 (2%)
Frame = +2
Query: 245 AAVYQDEEQVGQGIAEAIANGLVTREELFVTTK--LWNDKHARDQVVPALQESLKKLGLD 418
+A ++++E+ Q + + G R+ L V + + D ++ Q E LK+L +D
Sbjct: 332 SAFFEEQERRSQNSSISSTTGKSQRDSLIVIYQDAISFDDSSKTQSHSDAVEKLKQLQID 391
Query: 419 YIDLYLIHFPIATKPDDSP 475
D HF AT PDD P
Sbjct: 392 DPD----HFGSATLPDDDP 406
>AF449430-1|AAL47008.1| 905|Homo sapiens endocytosis protein HSTNB
variant protein.
Length = 905
Score = 29.9 bits (64), Expect = 10.0
Identities = 23/79 (29%), Positives = 38/79 (48%), Gaps = 2/79 (2%)
Frame = +2
Query: 245 AAVYQDEEQVGQGIAEAIANGLVTREELFVTTK--LWNDKHARDQVVPALQESLKKLGLD 418
+A ++++E+ Q + + G R+ L V + + D ++ Q E LK+L +D
Sbjct: 332 SAFFEEQERRSQNSSISSTTGKSQRDSLIVIYQDAISFDDSSKTQSHSDAVEKLKQLQID 391
Query: 419 YIDLYLIHFPIATKPDDSP 475
D HF AT PDD P
Sbjct: 392 DPD----HFGSATLPDDDP 406
>AF380833-1|AAK76362.1| 886|Homo sapiens endocytosis protein HSTNB
protein.
Length = 886
Score = 29.9 bits (64), Expect = 10.0
Identities = 23/79 (29%), Positives = 38/79 (48%), Gaps = 2/79 (2%)
Frame = +2
Query: 245 AAVYQDEEQVGQGIAEAIANGLVTREELFVTTK--LWNDKHARDQVVPALQESLKKLGLD 418
+A ++++E+ Q + + G R+ L V + + D ++ Q E LK+L +D
Sbjct: 313 SAFFEEQERRSQNSSISSTTGKSQRDSLIVIYQDAISFDDSSKTQSHSDAVEKLKQLQID 372
Query: 419 YIDLYLIHFPIATKPDDSP 475
D HF AT PDD P
Sbjct: 373 DPD----HFGSATLPDDDP 387
>AF255309-1|AAK57558.1| 702|Homo sapiens stonin 2 protein.
Length = 702
Score = 29.9 bits (64), Expect = 10.0
Identities = 23/79 (29%), Positives = 38/79 (48%), Gaps = 2/79 (2%)
Frame = +2
Query: 245 AAVYQDEEQVGQGIAEAIANGLVTREELFVTTK--LWNDKHARDQVVPALQESLKKLGLD 418
+A ++++E+ Q + + G R+ L V + + D ++ Q E LK+L +D
Sbjct: 129 SAFFEEQERRSQNSSISSTTGKSQRDSLIVIYQDAISFDDSSKTQSHSDAVEKLKQLQID 188
Query: 419 YIDLYLIHFPIATKPDDSP 475
D HF AT PDD P
Sbjct: 189 DPD----HFGSATLPDDDP 203
>AB208948-1|BAD92185.1| 932|Homo sapiens Stonin 2 variant protein.
Length = 932
Score = 29.9 bits (64), Expect = 10.0
Identities = 23/79 (29%), Positives = 38/79 (48%), Gaps = 2/79 (2%)
Frame = +2
Query: 245 AAVYQDEEQVGQGIAEAIANGLVTREELFVTTK--LWNDKHARDQVVPALQESLKKLGLD 418
+A ++++E+ Q + + G R+ L V + + D ++ Q E LK+L +D
Sbjct: 344 SAFFEEQERRSQNSSISSTTGKSQRDSLIVIYQDAISFDDSSKTQSHSDAVEKLKQLQID 403
Query: 419 YIDLYLIHFPIATKPDDSP 475
D HF AT PDD P
Sbjct: 404 DPD----HFGSATLPDDDP 418
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 112,392,746
Number of Sequences: 237096
Number of extensions: 2253811
Number of successful extensions: 5252
Number of sequences better than 10.0: 126
Number of HSP's better than 10.0 without gapping: 4876
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5073
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8791154398
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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