Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P11_pT_B16
(589 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
M18907-1|AAA35745.1| 503|Homo sapiens protein ( Human P450 mRNA... 135 9e-32
DQ924960-1|ABI96208.1| 503|Homo sapiens cytochrome P450 family ... 135 9e-32
DQ005611-1|AAY16980.1| 503|Homo sapiens cytochrome P450, family... 135 9e-32
BC101631-1|AAI01632.1| 503|Homo sapiens cytochrome P450, subfam... 135 9e-32
BC069418-1|AAH69418.1| 503|Homo sapiens cytochrome P450, family... 135 9e-32
AJ563377-1|CAD91345.1| 353|Homo sapiens cytochrome P450 protein. 135 9e-32
AJ563376-2|CAD91645.1| 430|Homo sapiens cytochrome P450 protein. 135 9e-32
AJ563375-1|CAD91343.1| 503|Homo sapiens cytochrome P450 protein. 135 9e-32
AF280107-2|AAG32290.1| 503|Homo sapiens cytochrome P450 polypep... 135 9e-32
AF209389-1|AAF21034.1| 503|Homo sapiens cytochrome P450 IIIA4 p... 135 9e-32
AF182273-1|AAF13598.1| 503|Homo sapiens cytochrome P450-3A4 pro... 135 9e-32
M14096-1|AAA35744.1| 503|Homo sapiens protein ( Human cytochrom... 135 1e-31
J04449-1|AAA35747.1| 502|Homo sapiens cytochrome P450 nifedipin... 135 1e-31
X12387-1|CAA30944.1| 503|Homo sapiens protein ( Human mRNA for ... 134 2e-31
M13785-1|AAA35742.1| 504|Homo sapiens protein ( Human liver glu... 134 2e-31
D00003-1|BAA00001.1| 504|Homo sapiens cytochrome P-450 protein. 134 2e-31
D00408-1|BAA00310.1| 503|Homo sapiens cytochrome P-450 HFLa pro... 129 6e-30
BC067436-1|AAH67436.1| 503|Homo sapiens cytochrome P450, family... 129 6e-30
AF315325-1|AAG48618.1| 535|Homo sapiens cytochrome P450 variant... 129 6e-30
AF280107-3|AAG32289.1| 503|Homo sapiens cytochrome P450 polypep... 129 6e-30
BC100981-1|AAI00982.1| 393|Homo sapiens CYP3A43 protein protein. 126 4e-29
AY390425-1|AAQ92353.1| 503|Homo sapiens cytochrome P450 CYP3A43... 126 4e-29
AY390424-1|AAQ92352.1| 503|Homo sapiens cytochrome P450 CYP3A43... 126 4e-29
AF337813-1|AAK38841.1| 503|Homo sapiens cytochrome P450 subfami... 126 4e-29
AF319634-1|AAK00325.1| 503|Homo sapiens cytochrome P450 CYP3A43... 126 4e-29
AF280108-1|AAG33009.1| 503|Homo sapiens cytochrome P450 subfami... 126 4e-29
AC011904-4|AAS07395.1| 503|Homo sapiens unknown protein. 126 4e-29
AK223008-1|BAD96728.1| 502|Homo sapiens cytochrome P450, family... 125 1e-28
J04813-1|AAA02993.1| 502|Homo sapiens cytochrome P450 PCN3 prot... 124 2e-28
BC033862-1|AAH33862.1| 502|Homo sapiens cytochrome P450, family... 124 2e-28
AJ563378-3|CAD91347.1| 173|Homo sapiens hypothetical protein pr... 124 2e-28
AJ563378-2|CAD91647.1| 160|Homo sapiens cytochrome P450 protein. 124 2e-28
AC005020-1|AAS02016.1| 502|Homo sapiens unknown protein. 124 2e-28
AF280109-1|AAG33010.1| 504|Homo sapiens cytochrome P450 subfami... 122 9e-28
AC011904-5|AAS07394.1| 504|Homo sapiens unknown protein. 122 9e-28
AF236085-1|AAG15889.1| 524|Homo sapiens CYP4F11 protein. 105 2e-22
BC016853-1|AAH16853.1| 524|Homo sapiens CYP4F11 protein protein. 104 3e-22
BC035350-1|AAH35350.1| 524|Homo sapiens cytochrome P450, family... 102 8e-22
AY358977-1|AAQ89336.1| 524|Homo sapiens CYP4F12 protein. 102 8e-22
AY008841-1|AAG33247.1| 524|Homo sapiens cytochrome P450 isoform... 102 8e-22
AC004523-1|AAC11543.1| 458|Homo sapiens F22329_1 protein. 102 8e-22
AB035131-1|BAB18270.1| 524|Homo sapiens cytochrome P450 protein. 102 8e-22
AB035130-1|BAB18269.1| 524|Homo sapiens cytochrome P450 protein. 102 8e-22
AF233624-1|AAF99278.1| 534|Homo sapiens thromboxane synthase pr... 101 1e-21
AF233623-1|AAF99277.1| 534|Homo sapiens thromboxane synthase pr... 101 1e-21
M80647-1|AAA60618.1| 534|Homo sapiens thromboxane synthase prot... 101 2e-21
BC041157-1|AAH41157.1| 534|Homo sapiens thromboxane A synthase ... 101 2e-21
BC014117-1|AAH14117.1| 466|Homo sapiens TBXAS1 protein protein. 101 2e-21
AK223466-1|BAD97186.1| 534|Homo sapiens thromboxane A synthase ... 101 2e-21
AF233621-1|AAF99275.1| 534|Homo sapiens thromboxane synthase pr... 101 2e-21
AF233620-1|AAF99274.1| 534|Homo sapiens thromboxane synthase pr... 101 2e-21
AF233619-1|AAF99273.1| 534|Homo sapiens thromboxane synthase pr... 101 2e-21
AF233618-1|AAF99272.1| 534|Homo sapiens thromboxane synthase pr... 101 2e-21
AF233617-1|AAF99271.1| 534|Homo sapiens thromboxane synthase pr... 101 2e-21
AF233616-1|AAF99270.1| 534|Homo sapiens thromboxane synthase pr... 101 2e-21
AF233615-1|AAF99269.1| 534|Homo sapiens thromboxane synthase pr... 101 2e-21
AF233625-1|AAF99279.1| 534|Homo sapiens thromboxane synthase pr... 101 2e-21
AF233622-1|AAF99276.1| 534|Homo sapiens thromboxane synthase pr... 100 4e-21
BC060857-1|AAH60857.1| 525|Homo sapiens cytochrome P450, family... 99 6e-21
AY422002-1|AAR31180.1| 525|Homo sapiens cytochrome P450 4V2 pro... 99 6e-21
AK126473-1|BAC86562.1| 503|Homo sapiens protein ( Homo sapiens ... 99 6e-21
AK122600-1|BAC85487.1| 525|Homo sapiens protein ( Homo sapiens ... 99 6e-21
D34625-1|BAA07011.1| 533|Homo sapiens thromboxane synthase prot... 100 8e-21
AF133298-1|AAD49566.1| 520|Homo sapiens cytochrome P450 protein. 99 1e-20
AY792513-1|AAV40834.1| 520|Homo sapiens cytochrome P450, family... 98 2e-20
AF054821-1|AAC08589.1| 520|Homo sapiens cytochrome P-450 protein. 98 2e-20
D12620-1|BAA02144.1| 520|Homo sapiens cytochrome P-450LTBV prot... 97 4e-20
AB002461-1|BAA25991.1| 520|Homo sapiens leukotriene B4 omega-hy... 97 4e-20
AB002454-1|BAA25990.1| 520|Homo sapiens leukotriene B4 omega-hy... 97 4e-20
X16699-1|CAA34672.1| 511|Homo sapiens protein ( Human mRNA for ... 95 2e-19
J02871-1|AAA35712.1| 511|Homo sapiens protein ( Human lung cyto... 95 2e-19
DQ518907-1|ABF47106.1| 511|Homo sapiens cytochrome P450, family... 95 2e-19
BC017758-1|AAH17758.1| 512|Homo sapiens cytochrome P450, family... 95 2e-19
AY358631-1|AAQ88994.1| 505|Homo sapiens EPSW3060 protein. 95 2e-19
AY262056-1|AAO89257.1| 505|Homo sapiens cytochrome P450 protein. 95 2e-19
AY151049-1|AAN72312.1| 497|Homo sapiens pulmonary cytochrome P4... 95 2e-19
AY151048-1|AAN72311.1| 512|Homo sapiens pulmonary cytochrome P4... 95 2e-19
AY064486-1|AAL57721.1| 511|Homo sapiens cytochrome P450 protein. 95 2e-19
AY064485-1|AAL57720.1| 511|Homo sapiens cytochrome P450 protein. 95 2e-19
AL593856-7|CAI16982.1| 512|Homo sapiens cytochrome P450, family... 95 2e-19
AL593856-6|CAI16981.1| 511|Homo sapiens cytochrome P450, family... 95 2e-19
AL593856-5|CAI16983.1| 497|Homo sapiens cytochrome P450, family... 95 2e-19
AL450996-2|CAH71036.1| 505|Homo sapiens cytochrome P450, family... 95 2e-19
AL356793-4|CAI22557.1| 512|Homo sapiens cytochrome P450, family... 95 2e-19
AL356793-3|CAI22559.1| 511|Homo sapiens cytochrome P450, family... 95 2e-19
AL356793-2|CAI22558.1| 497|Homo sapiens cytochrome P450, family... 95 2e-19
AL135960-6|CAI19734.1| 505|Homo sapiens cytochrome P450, family... 95 2e-19
AF491285-1|AAM09532.1| 511|Homo sapiens cytochrome P450 protein. 95 2e-19
BC067440-1|AAH67440.1| 520|Homo sapiens cytochrome P450, family... 94 4e-19
AB015306-1|BAA75823.1| 520|Homo sapiens Leukotriene B4 omega-hy... 94 4e-19
D26480-1|BAA05490.1| 520|Homo sapiens leukotriene B4 omega-hydr... 93 5e-19
BC067439-1|AAH67439.1| 520|Homo sapiens cytochrome P450, family... 93 5e-19
BC067437-1|AAH67437.1| 520|Homo sapiens cytochrome P450, family... 93 5e-19
AF467894-1|AAL67578.1| 520|Homo sapiens cytochrome P450, subfam... 93 5e-19
AC005336-1|AAC27730.1| 520|Homo sapiens CYP4F2 protein. 93 5e-19
U02388-1|AAC50052.2| 520|Homo sapiens cytochrome P450 4F2 protein. 92 1e-18
BC028102-1|AAH28102.1| 509|Homo sapiens cytochrome P450, family... 91 2e-18
AY358537-1|AAQ88901.1| 509|Homo sapiens EFSW1929 protein. 91 2e-18
AM040940-1|CAJ13826.1| 509|Homo sapiens cytochrome P450 protein. 91 2e-18
AL450996-1|CAH71035.1| 509|Homo sapiens cytochrome P450, family... 91 2e-18
AK131355-1|BAD18508.1| 508|Homo sapiens protein ( Homo sapiens ... 91 2e-18
AK098065-1|BAC05226.1| 509|Homo sapiens protein ( Homo sapiens ... 91 2e-18
AK091806-1|BAC03751.1| 444|Homo sapiens protein ( Homo sapiens ... 91 2e-18
BC093896-1|AAH93896.1| 531|Homo sapiens cytochrome P450, family... 87 6e-17
BC093894-1|AAH93894.1| 531|Homo sapiens cytochrome P450, family... 87 6e-17
BC069351-1|AAH69351.1| 531|Homo sapiens cytochrome P450, family... 87 6e-17
AK096820-1|BAC04868.1| 531|Homo sapiens protein ( Homo sapiens ... 87 6e-17
S67580-1|AAB29502.1| 519|Homo sapiens fatty acid omega-hydroxyl... 80 5e-15
S67581-1|AAB29503.1| 591|Homo sapiens fatty acid omega-hydroxyl... 80 7e-15
L04751-1|AAA58436.1| 519|Homo sapiens cytochrome P450 protein. 79 1e-14
D26481-1|BAA05491.1| 519|Homo sapiens fatty acids omega-hydroxy... 79 1e-14
AY369778-1|AAQ56847.1| 519|Homo sapiens cytochrome P450, family... 79 1e-14
AL731892-3|CAH72778.1| 519|Homo sapiens cytochrome P450, family... 79 1e-14
AF525488-1|AAO16078.1| 519|Homo sapiens cytochrome P450, subfam... 79 2e-14
AY280372-1|AAQ21368.1| 519|Homo sapiens cytochrome P450 4A22 pr... 77 4e-14
D13705-1|BAA02864.1| 521|Homo sapiens fatty acid omega-hydroxyl... 76 8e-14
AY280371-1|AAQ21367.1| 519|Homo sapiens cytochrome P450 4A22K p... 75 1e-13
AL135960-9|CAI19737.1| 519|Homo sapiens cytochrome P450, family... 75 2e-13
AF208532-1|AAF76722.1| 519|Homo sapiens fatty acid omega-hydrox... 75 2e-13
AL135960-10|CAI19736.1| 421|Homo sapiens cytochrome P450, famil... 74 4e-13
AY288916-1|AAP31972.1| 508|Homo sapiens cytochrome P450, family... 73 6e-13
AF256213-1|AAG00416.1| 508|Homo sapiens 25- hydroxyvitamin D-1-... 73 6e-13
AF246895-1|AAF64299.1| 508|Homo sapiens 25-hydroxyvitamin D-1-a... 73 6e-13
AF027152-1|AAC51854.1| 508|Homo sapiens P450 25-hydroxyvitamin ... 73 6e-13
AF020192-1|AAC51853.1| 508|Homo sapiens 25-hydroxyvitamin D-1-a... 73 6e-13
AB006987-1|BAA23418.1| 508|Homo sapiens 25-hydroxyvitamin D3 1-... 73 6e-13
AB005990-1|BAA22657.1| 508|Homo sapiens 25-hydroxyvitamin D3 1a... 73 6e-13
AB005989-1|BAA22656.1| 508|Homo sapiens 25-hydroxyvitamin D3 1a... 73 6e-13
AB005038-1|BAA23416.1| 508|Homo sapiens 25-hydroxyvitamin D3 1-... 73 6e-13
X05367-1|CAA28965.1| 521|Homo sapiens desmolase protein. 68 2e-11
M28253-1|AAA36404.1| 239|Homo sapiens cytochrome P-450-scc prot... 68 2e-11
M14565-1|AAA52162.1| 521|Homo sapiens CYP11A protein. 68 2e-11
BC032329-1|AAH32329.1| 521|Homo sapiens cytochrome P450, family... 68 2e-11
BC022539-1|AAH22539.1| 500|Homo sapiens cytochrome P450, family... 68 2e-11
AF094480-1|AAD41244.1| 500|Homo sapiens cholesterol 24-hydroxyl... 68 2e-11
AJ563379-2|CAD91649.1| 84|Homo sapiens cytochrome P450 protein. 68 3e-11
M32879-1|AAA52149.1| 503|Homo sapiens CYP11B1 protein. 67 5e-11
BC096287-1|AAH96287.1| 503|Homo sapiens cytochrome P450, family... 67 5e-11
BC096285-1|AAH96285.1| 574|Homo sapiens CYP11B1 protein protein. 67 5e-11
AF478474-1|AAL84813.1| 503|Homo sapiens mutated cytochrome P-45... 67 5e-11
X55764-1|CAA39290.1| 503|Homo sapiens protein ( Human mRNA for ... 66 7e-11
M63871-1|AAA59984.1| 508|Homo sapiens CYP17 protein. 66 1e-10
M31153-1|AAA52140.1| 508|Homo sapiens CYP17 protein. 66 1e-10
M19489-1|AAA36405.1| 508|Homo sapiens CYP17 protein. 66 1e-10
M14564-1|AAA52151.1| 508|Homo sapiens CYP17 protein. 66 1e-10
DQ530598-1|ABF50972.1| 508|Homo sapiens cytochrome P450, family... 66 1e-10
BT020000-1|AAV38803.1| 508|Homo sapiens cytochrome P450, family... 66 1e-10
BC063388-1|AAH63388.1| 508|Homo sapiens cytochrome P450, family... 66 1e-10
BC062997-1|AAH62997.1| 508|Homo sapiens cytochrome P450, family... 66 1e-10
AL358790-3|CAI52498.1| 508|Homo sapiens cytochrome P450, family... 66 1e-10
AL358613-3|CAH72804.1| 428|Homo sapiens cytochrome P450, family... 64 5e-10
AL358613-2|CAH72803.1| 497|Homo sapiens cytochrome P450, family... 64 5e-10
AF005418-1|AAB88881.1| 497|Homo sapiens retinoic acid hydroxyla... 64 5e-10
AK090886-1|BAC03539.1| 337|Homo sapiens protein ( Homo sapiens ... 63 6e-10
BC039307-1|AAH39307.1| 372|Homo sapiens cytochrome P450, family... 63 8e-10
AK131190-1|BAD18388.1| 372|Homo sapiens .-.-). protein. 63 8e-10
BC132767-1|AAI32768.1| 544|Homo sapiens cytochrome P450, family... 62 2e-09
AY343323-1|AAQ21380.1| 544|Homo sapiens cytochrome P450 protein. 62 2e-09
BC109205-1|AAI09206.1| 512|Homo sapiens cytochrome P450, family... 61 3e-09
BC069443-1|AAH69443.1| 512|Homo sapiens cytochrome P450, family... 61 3e-09
BC032322-1|AAH32322.1| 509|Homo sapiens cytochrome P450, family... 61 3e-09
AF252297-1|AAF76003.1| 512|Homo sapiens cytochrome P450 retinoi... 61 3e-09
AC007002-1|AAY14690.1| 512|Homo sapiens unknown protein. 61 3e-09
X54741-1|CAA38539.1| 503|Homo sapiens aldosterone synthase (P-... 60 4e-09
U23942-1|AAB39951.1| 509|Homo sapiens lanosterol 14-demethylase... 60 4e-09
D55653-1|BAA09512.1| 509|Homo sapiens lanosterol 14-demethylase... 60 4e-09
D13752-1|BAA02899.1| 503|Homo sapiens steroid 18-hydroxylase pr... 60 4e-09
AC000120-2|AAB46356.1| 509|Homo sapiens unknown protein. 60 4e-09
U51692-1|AAC50951.1| 503|Homo sapiens lanosterol 14-alpha demet... 60 6e-09
S67623-1|AAB29308.1| 257|Homo sapiens 25-hydroxyvitamin D 24-hy... 60 6e-09
AY858838-1|AAW50795.1| 372|Homo sapiens vitamin D 24-hydroxylas... 60 6e-09
AL138805-2|CAB91829.1| 514|Homo sapiens cytochrome P450, family... 60 6e-09
AL138805-1|CAM27342.1| 372|Homo sapiens cytochrome P450, family... 60 6e-09
X71480-1|CAA50586.1| 141|Homo sapiens cytochrome P450 protein. 60 8e-09
L13286-1|AAA62379.1| 513|Homo sapiens 1,25-dihydroxyvitamin D3 ... 60 8e-09
BC100982-1|AAI00983.1| 280|Homo sapiens CYP3A43 protein protein. 59 1e-08
AF280110-1|AAG33011.1| 420|Homo sapiens cytochrome P450 subfami... 59 1e-08
X13930-1|CAA32118.1| 494|Homo sapiens protein ( Human CYP2A4 mR... 59 1e-08
X13929-1|CAA32117.1| 448|Homo sapiens P-450 IIA3 protein (1 is ... 59 1e-08
X13897-1|CAA32097.1| 489|Homo sapiens protein ( Human mRNA for ... 59 1e-08
M33318-1|AAA52067.1| 494|Homo sapiens CYP2A protein. 59 1e-08
BC096256-1|AAH96256.1| 494|Homo sapiens cytochrome P450, family... 59 1e-08
BC096255-1|AAH96255.1| 494|Homo sapiens cytochrome P450, family... 59 1e-08
BC096254-1|AAH96254.1| 494|Homo sapiens cytochrome P450, family... 59 1e-08
BC096253-1|AAH96253.3| 494|Homo sapiens cytochrome P450, family... 59 1e-08
AF182275-1|AAF13600.1| 494|Homo sapiens cytochrome P450-2A6 pro... 59 1e-08
M24667-1|AAA52148.1| 256|Homo sapiens steroid 11-beta-hydroxyla... 58 2e-08
M93133-1|AAA58435.1| 504|Homo sapiens cholesterol 7-alpha hydro... 57 5e-08
EF122241-1|ABO41976.1| 491|Homo sapiens cytochrome P450 2F1 var... 57 5e-08
BC112184-1|AAI12185.1| 504|Homo sapiens cytochrome P450, family... 57 5e-08
BC101777-1|AAI01778.1| 504|Homo sapiens cytochrome P450, family... 57 5e-08
AF372573-1|AAL69652.1| 495|Homo sapiens cytochrome P450 2F1 pro... 57 5e-08
Y07508-1|CAA68807.1| 503|Homo sapiens protein ( Human mRNA for ... 56 7e-08
X13589-1|CAA31929.1| 503|Homo sapiens protein ( Human mRNA for ... 56 7e-08
M30804-1|AAA35728.1| 503|Homo sapiens protein ( Human aromatase... 56 7e-08
M28420-1|AAA52141.1| 419|Homo sapiens cytochrome P-450 aromatas... 56 7e-08
M22246-1|AAA35557.1| 503|Homo sapiens protein ( Human aromatase... 56 7e-08
M18856-1|AAA35556.1| 419|Homo sapiens protein ( Human aromatase... 56 7e-08
J04127-1|AAA52132.1| 503|Homo sapiens CYP19 protein. 56 7e-08
J02906-1|AAA52156.1| 491|Homo sapiens CYP2F1 protein. 56 7e-08
DQ118405-1|AAZ23558.1| 503|Homo sapiens cytochrome P450 subfami... 56 7e-08
BC107785-1|AAI07786.1| 503|Homo sapiens cytochrome P450, family... 56 7e-08
BC104909-1|AAI04910.1| 501|Homo sapiens cytochrome P450, family... 56 7e-08
BC104907-1|AAI04908.1| 501|Homo sapiens cytochrome P450, family... 56 7e-08
BC035959-1|AAH35959.1| 503|Homo sapiens cytochrome P450, family... 56 7e-08
AY957953-1|AAX44046.1| 503|Homo sapiens cytochrome P450, family... 56 7e-08
AY323817-1|AAQ23114.1| 501|Homo sapiens cytochrome P450 2R1 pro... 56 7e-08
AL358613-1|CAH72802.2| 522|Homo sapiens cytochrome P450, family... 56 9e-08
X56088-1|CAA39568.1| 504|Homo sapiens cholesterol 7-alpha-hydr... 56 1e-07
X08006-1|CAA30807.1| 497|Homo sapiens cytochrome P450 db1 protein. 56 1e-07
M33388-1|AAA53500.1| 497|Homo sapiens cytochrome P450 IID6 prot... 56 1e-07
M33189-1|AAA35737.1| 500|Homo sapiens protein ( Human debrisoqu... 56 1e-07
M24499-1|AAA36403.1| 373|Homo sapiens cytochrome P450db1 protein. 56 1e-07
M20403-1|AAA52153.1| 497|Homo sapiens CYP2D protein. 56 1e-07
DQ282162-1|ABB77909.1| 500|Homo sapiens cytochrome P450 2D6 pro... 56 1e-07
DQ282160-1|ABB77908.1| 497|Homo sapiens cytochrome P450 2D6 pro... 56 1e-07
DQ282159-1|ABB77907.1| 497|Homo sapiens cytochrome P450 2D6 pro... 56 1e-07
DQ282158-1|ABB77906.1| 497|Homo sapiens cytochrome P450 2D6 pro... 56 1e-07
DQ282157-1|ABB77905.1| 497|Homo sapiens cytochrome P450 2D6 pro... 56 1e-07
DQ282156-1|ABB77904.1| 497|Homo sapiens cytochrome P450 2D6 pro... 56 1e-07
DQ282155-1|ABB77903.1| 497|Homo sapiens cytochrome P450 2D6 pro... 56 1e-07
DQ282154-1|ABB77902.1| 497|Homo sapiens cytochrome P450 2D6 pro... 56 1e-07
DQ282153-1|ABB77901.1| 497|Homo sapiens cytochrome P450 2D6 pro... 56 1e-07
DQ282152-1|ABB77900.1| 497|Homo sapiens cytochrome P450 2D6 pro... 56 1e-07
DQ282151-1|ABB77899.1| 496|Homo sapiens cytochrome P450 2D6 pro... 56 1e-07
DQ282147-1|ABB77898.1| 497|Homo sapiens cytochrome P450 2D6 pro... 56 1e-07
DQ282146-1|ABB77897.1| 497|Homo sapiens cytochrome P450 2D6 pro... 56 1e-07
DQ282145-1|ABB77896.1| 497|Homo sapiens cytochrome P450 2D6 pro... 56 1e-07
DQ282144-1|ABB77895.1| 497|Homo sapiens cytochrome P450 2D6 pro... 56 1e-07
DQ211354-2|ABB01372.1| 497|Homo sapiens cytochrome P450 2D6 pro... 56 1e-07
DQ211353-2|ABB01371.1| 497|Homo sapiens cytochrome P450 2D6 pro... 56 1e-07
DQ211353-1|ABB01370.1| 497|Homo sapiens cytochrome P450 2D6 pro... 56 1e-07
CR456430-1|CAG30316.1| 446|Homo sapiens CYP2D6 protein. 56 1e-07
BC126858-1|AAI26859.1| 497|Homo sapiens cytochrome P450, family... 56 1e-07
BC106758-1|AAI06759.1| 497|Homo sapiens cytochrome P450, family... 56 1e-07
BC106757-1|AAI06758.1| 446|Homo sapiens cytochrome P450, family... 56 1e-07
BC075024-1|AAH75024.1| 497|Homo sapiens cytochrome P450, family... 56 1e-07
BC075023-1|AAH75023.1| 497|Homo sapiens cytochrome P450, family... 56 1e-07
BC067432-1|AAH67432.1| 497|Homo sapiens cytochrome P450, family... 56 1e-07
BC066877-1|AAH66877.1| 446|Homo sapiens CYP2D6 protein protein. 56 1e-07
AY545216-1|AAS55001.1| 497|Homo sapiens cytochrome P4502D6 prot... 56 1e-07
AY220845-1|AAO49806.1| 516|Homo sapiens cytochrome P450 protein. 56 1e-07
AB209492-1|BAD92729.1| 566|Homo sapiens Debrisoquine 4-hydroxyl... 56 1e-07
M33317-1|AAA52138.1| 494|Homo sapiens CYP2A protein. 55 2e-07
BC117165-1|AAI17166.1| 494|Homo sapiens cytochrome P450, family... 55 2e-07
M32881-1|AAA35741.1| 503|Homo sapiens protein ( Human steroid 1... 55 2e-07
AY513609-1|AAR90940.1| 494|Homo sapiens cytochrome P450 2A13 va... 54 3e-07
AY513608-1|AAR90939.1| 494|Homo sapiens cytochrome P450 2A13 va... 54 3e-07
AY513606-1|AAR90937.1| 494|Homo sapiens cytochrome P450 2A13 va... 54 3e-07
AY513605-1|AAR90936.1| 494|Homo sapiens cytochrome P450 2A13 va... 54 3e-07
AY513604-1|AAR90935.1| 494|Homo sapiens cytochrome P450 2A13 va... 54 3e-07
AF209774-1|AAG35775.1| 494|Homo sapiens cytochrome P450 2A13 pr... 54 3e-07
AY356349-1|AAQ55485.1| 522|Homo sapiens cytochrome P450 protein. 54 5e-07
AF176805-1|AAK11850.1| 506|Homo sapiens oxysterol 7alpha-hydrox... 53 7e-07
AF127090-1|AAD20021.1| 506|Homo sapiens oxysterol 7alpha-hydrox... 53 7e-07
AF029403-1|AAC95426.1| 506|Homo sapiens oxysterol 7alpha-hydrox... 53 7e-07
J02843-1|AAA52155.1| 493|Homo sapiens protein ( Human cytochrom... 53 9e-07
J02625-1|AAA35743.1| 493|Homo sapiens protein ( Human cytochrom... 53 9e-07
DQ515958-1|ABF47105.1| 493|Homo sapiens cytochrome P450, family... 53 9e-07
DQ149222-1|AAZ77710.1| 493|Homo sapiens cytochrome P450 2E1 pro... 53 9e-07
BC142607-1|AAI42608.1| 455|Homo sapiens CYP4A22 protein protein. 53 9e-07
BC067435-1|AAH67435.1| 493|Homo sapiens cytochrome P450, family... 53 9e-07
BC067433-1|AAH67433.1| 493|Homo sapiens cytochrome P450, family... 53 9e-07
BC033691-1|AAH33691.1| 504|Homo sapiens cytochrome P450, family... 53 9e-07
BC010358-1|AAH10358.1| 469|Homo sapiens cytochrome P450, family... 53 9e-07
AY358603-1|AAQ88966.1| 504|Homo sapiens Cytochrome p450 protein. 53 9e-07
AL591242-1|CAH73899.1| 469|Homo sapiens cytochrome P450, family... 53 9e-07
AL161645-2|CAH70047.1| 493|Homo sapiens cytochrome P450, family... 53 9e-07
AL035670-1|CAI20276.1| 469|Homo sapiens cytochrome P450, family... 53 9e-07
AK027605-1|BAB55227.1| 564|Homo sapiens protein ( Homo sapiens ... 53 9e-07
AF335278-1|AAK13498.1| 504|Homo sapiens cytochrome P450 2S1 pro... 53 9e-07
AF182276-1|AAF13601.1| 493|Homo sapiens cytochrome P450-2E1 pro... 53 9e-07
AF084225-1|AAD13753.1| 462|Homo sapiens cytochrome P450 2E1 pro... 53 9e-07
U37143-1|AAC50370.2| 502|Homo sapiens cytochrome P450 monooxyge... 52 1e-06
BC032594-1|AAH32594.1| 502|Homo sapiens cytochrome P450, family... 52 1e-06
AY426985-1|AAQ93356.1| 502|Homo sapiens cytochrome P450, family... 52 1e-06
AF272142-1|AAM44456.1| 502|Homo sapiens cytochrome P450 protein. 52 1e-06
AB080265-1|BAB85489.1| 502|Homo sapiens cytochrome P450 2J2 pro... 52 1e-06
U22028-1|AAB40519.1| 494|Homo sapiens cytochrome P450 protein. 52 2e-06
BC041158-1|AAH41158.1| 455|Homo sapiens CYP4A11 protein protein. 52 2e-06
AL731892-4|CAH72779.1| 455|Homo sapiens cytochrome P450, family... 52 2e-06
M21939-1|AAA52158.1| 485|Homo sapiens CYP2C protein. 51 3e-06
M15331-1|AAA52157.1| 485|Homo sapiens CYP2C protein. 51 3e-06
K03192-1|AAA52147.1| 331|Homo sapiens CYP1A1 protein. 51 3e-06
BC067441-1|AAH67441.1| 501|Homo sapiens cytochrome P450, family... 51 3e-06
BC067434-1|AAH67434.1| 501|Homo sapiens cytochrome P450, family... 51 3e-06
S46963-1|AAB23864.2| 477|Homo sapiens cytochrome P-450 protein. 51 3e-06
M21940-1|AAA52159.1| 383|Homo sapiens CYP2C protein. 51 3e-06
L16883-1|AAD13467.1| 169|Homo sapiens cytochrome P-450 2C protein. 51 3e-06
D00173-1|BAA00123.1| 487|Homo sapiens cytochrome P-450 protein. 51 3e-06
BC125054-1|AAI25055.1| 490|Homo sapiens cytochrome P450, family... 51 3e-06
BC067444-1|AAH67444.1| 501|Homo sapiens cytochrome P450, family... 51 3e-06
BC067442-1|AAH67442.1| 501|Homo sapiens cytochrome P450, family... 51 3e-06
AY702706-1|AAT94065.1| 490|Homo sapiens cytochrome P450, family... 51 3e-06
AY341248-1|AAP88931.1| 490|Homo sapiens cytochrome P450, family... 51 3e-06
AL359672-1|CAH71303.1| 490|Homo sapiens cytochrome P450, family... 51 3e-06
AF090320-1|AAD19877.1| 501|Homo sapiens sterol 12-alpha-hydroxy... 51 3e-06
AF090318-1|AAC63037.1| 462|Homo sapiens sterol 12-alpha hydroxy... 51 3e-06
U22029-1|AAB40520.1| 494|Homo sapiens cytochrome P450 protein. 50 5e-06
AF237982-1|AAF63329.1| 469|Homo sapiens oxysterol 7alpha-hydrox... 50 5e-06
Z00036-1|CAA77335.1| 515|Homo sapiens protein ( Human mRNA for ... 50 8e-06
X59812-1|CAA42481.1| 530|Homo sapiens Vitamin D3 25-hydroxylase... 50 8e-06
M62401-1|AAA52142.1| 531|Homo sapiens sterol 27-hydroxylase pro... 50 8e-06
M55053-1|AAA52146.1| 515|Homo sapiens cytochrome P3-450 protein. 50 8e-06
M31667-1|AAA52163.1| 515|Homo sapiens CYP1A2 protein. 50 8e-06
L00389-1|AAA35738.1| 516|Homo sapiens protein ( Human cytochrom... 50 8e-06
DQ022432-1|AAY26399.1| 516|Homo sapiens cytochrome P450, family... 50 8e-06
BC067429-1|AAH67429.1| 516|Homo sapiens cytochrome P450, family... 50 8e-06
BC067428-1|AAH67428.1| 516|Homo sapiens cytochrome P450, family... 50 8e-06
BC067427-1|AAH67427.1| 516|Homo sapiens cytochrome P450, family... 50 8e-06
BC067426-1|AAH67426.1| 516|Homo sapiens cytochrome P450, family... 50 8e-06
BC067425-1|AAH67425.1| 516|Homo sapiens cytochrome P450, family... 50 8e-06
BC067424-1|AAH67424.1| 516|Homo sapiens cytochrome P450, family... 50 8e-06
BC051851-1|AAH51851.1| 531|Homo sapiens cytochrome P450, family... 50 8e-06
BC040430-1|AAH40430.1| 531|Homo sapiens cytochrome P450, family... 50 8e-06
BC025761-1|AAH25761.2| 490|Homo sapiens cytochrome P450, family... 50 8e-06
AF253322-2|AAK25728.1| 516|Homo sapiens cytochrome P450 protein. 50 8e-06
AF182274-1|AAF13599.1| 516|Homo sapiens cytochrome P450-1A2 pro... 50 8e-06
AY178622-1|AAO21126.1| 531|Homo sapiens steroid hydroxylase pro... 49 1e-05
BC029155-1|AAH29155.1| 489|Homo sapiens CYP7B1 protein protein. 49 1e-05
AL135960-11|CAI19738.1| 455|Homo sapiens cytochrome P450, famil... 49 1e-05
X65962-1|CAA46778.1| 356|Homo sapiens cytochrome P-450 II C pro... 48 2e-05
U22027-1|AAB40518.1| 494|Homo sapiens cytochrome P450 protein. 48 2e-05
M80646-1|AAA60617.1| 460|Homo sapiens thromboxane synthase prot... 48 2e-05
M61858-1|AAA52145.1| 370|Homo sapiens CYP2C17 protein. 48 2e-05
M61854-1|AAB59426.1| 490|Homo sapiens cytochrome protein. 48 2e-05
L39102-1|AAL31348.1| 217|Homo sapiens S-mephenytoin 4-hydroxyla... 48 2e-05
L07093-1|AAA36660.1| 468|Homo sapiens cytochrome P450 protein. 48 2e-05
BC142690-1|AAI42691.1| 357|Homo sapiens CYP4A22 protein protein. 48 2e-05
AY796203-1|AAV41877.1| 490|Homo sapiens cytochrome P450, family... 48 2e-05
AL583836-2|CAH74068.1| 490|Homo sapiens cytochrome P450, family... 48 2e-05
AL133513-2|CAH73444.1| 490|Homo sapiens cytochrome P450, family... 48 2e-05
M61856-1|AAB59356.1| 490|Homo sapiens cytochrome protein. 47 4e-05
BX538127-1|CAD98029.1| 310|Homo sapiens hypothetical protein pr... 47 4e-05
BC096260-1|AAH96260.1| 431|Homo sapiens CYP2C18 protein protein. 47 4e-05
BC096258-1|AAH96258.1| 490|Homo sapiens cytochrome P450, family... 47 4e-05
BC096257-1|AAH96257.1| 490|Homo sapiens cytochrome P450, family... 47 4e-05
BC069666-1|AAH69666.1| 490|Homo sapiens cytochrome P450, family... 47 4e-05
AL583836-1|CAH74067.1| 490|Homo sapiens cytochrome P450, family... 47 4e-05
AK223510-1|BAD97230.1| 490|Homo sapiens cytochrome P450, family... 47 4e-05
Y00498-1|CAA68550.1| 490|Homo sapiens IIC2 protein. 46 1e-04
M21942-1|AAA52161.1| 462|Homo sapiens CYP2C protein. 46 1e-04
M17397-1|AAA35739.1| 490|Homo sapiens protein ( Human cytochrom... 46 1e-04
M12078-1|AAA52154.1| 192|Homo sapiens POR protein. 46 1e-04
D84124-1|BAA28219.1| 509|Homo sapiens prostacyclin synthase pro... 46 1e-04
D83402-1|BAA11910.1| 500|Homo sapiens prostacyclin synthase pro... 46 1e-04
D38145-1|BAA07343.1| 500|Homo sapiens prostacyclin synthase pro... 46 1e-04
BC101811-1|AAI01812.1| 500|Homo sapiens prostaglandin I2 (prost... 46 1e-04
BC101809-1|AAI01810.1| 500|Homo sapiens prostaglandin I2 (prost... 46 1e-04
BC020596-1|AAH20596.1| 490|Homo sapiens cytochrome P450, family... 46 1e-04
AY514490-1|AAR89907.1| 490|Homo sapiens cytochrome P450, family... 46 1e-04
AL359672-5|CAH71307.1| 490|Homo sapiens cytochrome P450, family... 46 1e-04
AL118525-1|CAC14162.1| 500|Homo sapiens prostaglandin I2 (prost... 46 1e-04
AK127234-1|BAC86895.1| 130|Homo sapiens ). protein. 46 1e-04
AK127151-1|BAC86855.1| 146|Homo sapiens protein ( Homo sapiens ... 46 1e-04
AF297051-1|AAG31784.1| 500|Homo sapiens prostacyclin synthase p... 46 1e-04
AF297050-1|AAG31783.1| 500|Homo sapiens prostacyclin synthase p... 46 1e-04
AF297049-1|AAG31782.1| 500|Homo sapiens prostacyclin synthase p... 46 1e-04
AF297048-1|AAG31781.1| 500|Homo sapiens prostacyclin synthase p... 46 1e-04
X51535-1|CAA35915.1| 210|Homo sapiens cytochrome P-450 HPH (120... 46 1e-04
M29874-1|AAA52144.1| 491|Homo sapiens CYP2B protein. 45 2e-04
M21941-1|AAA52160.1| 480|Homo sapiens CYP2C protein. 45 2e-04
DQ298753-1|ABB84469.1| 491|Homo sapiens cytochrome P450, family... 45 2e-04
BC067431-1|AAH67431.1| 491|Homo sapiens cytochrome P450, family... 45 2e-04
BC067430-1|AAH67430.1| 491|Homo sapiens cytochrome P450, family... 45 2e-04
AF297052-1|AAG31785.1| 500|Homo sapiens prostacyclin synthase p... 45 2e-04
AF182277-1|AAF13602.1| 491|Homo sapiens cytochrome P450-2B6 pro... 45 2e-04
AC023172-1|AAF32444.1| 491|Homo sapiens CYP2B6 protein. 45 2e-04
X04300-1|CAA27843.1| 512|Homo sapiens P-450 c protein. 45 2e-04
L16876-1|AAA02630.1| 490|Homo sapiens cytochrome P-4502C18 prot... 45 2e-04
EF094025-1|ABK41999.1| 512|Homo sapiens cytochrome P450, family... 45 2e-04
BC023019-1|AAH23019.1| 512|Homo sapiens cytochrome P450, family... 45 2e-04
AY310359-1|AAQ76692.1| 484|Homo sapiens cytochrome P450 1A1 var... 45 2e-04
AM236047-1|CAJ84704.1| 251|Homo sapiens cytochrome P450 1A1 pro... 45 2e-04
AK223113-1|BAD96833.1| 512|Homo sapiens cytochrome P450, family... 45 2e-04
AF253322-1|AAK25727.1| 512|Homo sapiens cytochrome P450 protein. 45 2e-04
X02612-1|CAA26458.1| 512|Homo sapiens cytochrome P(1)-450 protein. 44 3e-04
M12079-1|AAA52152.1| 191|Homo sapiens POR protein. 44 3e-04
K03191-1|AAA52139.1| 512|Homo sapiens CYP1A1 protein. 44 3e-04
EF122244-1|ABO41979.1| 216|Homo sapiens cytochrome P450 2F1 var... 44 3e-04
AK223108-1|BAD96828.1| 512|Homo sapiens cytochrome P450, family... 44 4e-04
AC005336-2|AAC27731.1| 93|Homo sapiens F20191_1, partial CDS p... 43 7e-04
U03688-1|AAA19567.1| 543|Homo sapiens cytochrome P450 protein. 40 0.005
BT020001-1|AAV38804.1| 543|Homo sapiens cytochrome P450, family... 40 0.005
BT019979-1|AAV38782.1| 543|Homo sapiens cytochrome P450, family... 40 0.005
BC012049-1|AAH12049.1| 543|Homo sapiens cytochrome P450, family... 40 0.005
AJ877238-1|CAI47002.1| 97|Homo sapiens putative cytochrome P45... 40 0.005
AC009229-2|AAY15039.1| 543|Homo sapiens unknown protein. 40 0.005
U56438-1|AAC50809.1| 543|Homo sapiens dioxin-inducible cytochro... 40 0.007
DQ016495-1|AAY34975.1| 195|Homo sapiens cytochrome P450 1B1 pro... 40 0.007
BC093022-1|AAH93022.1| 416|Homo sapiens CYP20A1 protein protein. 40 0.007
BC033752-1|AAH33752.1| 462|Homo sapiens cytochrome P450, family... 40 0.007
BC020616-1|AAH20616.1| 462|Homo sapiens cytochrome P450, family... 40 0.007
AY393998-1|AAQ87875.1| 543|Homo sapiens cytochrome P450, family... 40 0.007
AY359068-1|AAQ89427.1| 462|Homo sapiens P450-like protein protein. 40 0.007
AF450132-1|AAM50512.1| 543|Homo sapiens cytochrome P450 CYP1B1 ... 40 0.007
AF183412-1|AAG09681.1| 435|Homo sapiens cytochrome P450 monooxy... 40 0.007
M28548-1|AAA52065.1| 495|Homo sapiens protein ( Human mutant 21... 38 0.035
M26856-1|AAA52064.1| 495|Homo sapiens protein ( Human 21-hydrox... 38 0.035
M21550-1|AAA52063.1| 495|Homo sapiens CYP21 protein. 38 0.035
M17252-1|AAA59985.1| 230|Homo sapiens CYP21 protein. 38 0.035
M13936-1|AAA59695.1| 494|Homo sapiens CYP21P protein. 38 0.035
BX679671-8|CAM26070.1| 494|Homo sapiens cytochrome P450, family... 38 0.035
BX679671-7|CAM26071.1| 464|Homo sapiens cytochrome P450, family... 38 0.035
BC128535-1|AAI28536.1| 143|Homo sapiens CYP21A2 protein protein. 38 0.035
BC125182-1|AAI25183.1| 494|Homo sapiens cytochrome P450, family... 38 0.035
BC125181-1|AAI25182.1| 495|Homo sapiens cytochrome P450, family... 38 0.035
AM183951-1|CAJ75805.1| 494|Homo sapiens steroid 21-hydroxylase,... 38 0.035
AM183950-1|CAJ75804.1| 494|Homo sapiens steroid 21-hydroxylase,... 38 0.035
AM183949-1|CAJ75803.1| 494|Homo sapiens steroid 21-hydroxylase,... 38 0.035
AM183948-1|CAJ75802.1| 494|Homo sapiens steroid 21-hydroxylase ... 38 0.035
AM183947-1|CAJ75801.1| 494|Homo sapiens steroid 21-hydroxylase,... 38 0.035
AM183946-1|CAJ75800.1| 494|Homo sapiens steroid 21-hydroxylase,... 38 0.035
AM183945-1|CAJ75799.1| 494|Homo sapiens steroid 21-hydroxylase,... 38 0.035
AM086565-1|CAJ31104.1| 494|Homo sapiens steroid 21-hydroxylase,... 38 0.035
AM086564-1|CAJ31103.1| 494|Homo sapiens steroid 21-hydroxylase,... 38 0.035
AL929593-2|CAI41778.1| 465|Homo sapiens cytochrome P450, family... 38 0.035
AL929593-1|CAI41779.1| 495|Homo sapiens cytochrome P450, family... 38 0.035
AL662849-19|CAI17480.1| 465|Homo sapiens cytochrome P450, famil... 38 0.035
AL662849-18|CAI17479.1| 495|Homo sapiens cytochrome P450, famil... 38 0.035
AL645922-24|CAI41754.1| 495|Homo sapiens cytochrome P450, famil... 38 0.035
AL645922-23|CAI41755.1| 465|Homo sapiens cytochrome P450, famil... 38 0.035
AL049547-7|CAB89301.1| 495|Homo sapiens dJ34F7.3 (cytochrome P4... 38 0.035
AK054616-1|BAB70774.1| 465|Homo sapiens protein ( Homo sapiens ... 38 0.035
AF077974-1|AAD45405.1| 403|Homo sapiens cytochrome P450 21-hydr... 38 0.035
AF019413-2|AAB67982.1| 495|Homo sapiens cytochrome P450 21-hydr... 38 0.035
EF122243-1|ABO41978.1| 47|Homo sapiens cytochrome P450 2F1 var... 36 0.080
X58906-1|CAA41709.1| 495|Homo sapiens steroid 21-monooxygenase ... 36 0.11
BC096259-1|AAH96259.1| 443|Homo sapiens CYP2C18 protein protein. 36 0.11
AB209700-1|BAD92937.1| 336|Homo sapiens cytochrome P450, family... 35 0.19
M12792-1|AAB59440.1| 494|Homo sapiens steroid 21-hydroxylase pr... 33 0.57
L36085-1|AAC01761.1| 441|Homo sapiens thromboxane A2 synthase p... 33 0.57
AY871801-1|AAX62803.1| 483|Homo sapiens cytochrome P450 family ... 33 0.57
AK000366-1|BAA91114.1| 408|Homo sapiens protein ( Homo sapiens ... 32 1.3
BC000567-1|AAH00567.1| 809|Homo sapiens SEZ6L2 protein protein. 30 7.0
AY358404-1|AAQ88770.1| 910|Homo sapiens PSK-1 protein. 30 7.0
AJ245822-1|CAB57952.1| 840|Homo sapiens type I transmembrane re... 30 7.0
AJ245821-1|CAB57951.1| 580|Homo sapiens putative secreted molec... 30 7.0
AJ245820-1|CAB57950.1| 853|Homo sapiens type I transmembrane re... 30 7.0
D86987-1|BAA34389.2| 790|Homo sapiens KIAA0214 protein protein. 29 9.2
BC017061-1|AAH17061.1| 757|Homo sapiens mitofusin 2 protein. 29 9.2
AY028429-1|AAK18728.1| 757|Homo sapiens mitochondrial assembly ... 29 9.2
AL096840-8|CAI19087.2| 757|Homo sapiens mitofusin 2 protein. 29 9.2
AF036536-1|AAD02058.2| 757|Homo sapiens CPRP1 protein. 29 9.2
>M18907-1|AAA35745.1| 503|Homo sapiens protein ( Human P450 mRNA
encoding nifedipine oxidase, complete cds. ).
Length = 503
Score = 135 bits (327), Expect = 9e-32
Identities = 64/140 (45%), Positives = 92/140 (65%)
Frame = -3
Query: 581 YNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPV 402
Y+++ M YLDMVV+E LRL+P + ++R+C +D + + KG V IP
Sbjct: 347 YDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEIN--------GMFIPKGVVVMIPS 398
Query: 401 WAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQ 222
+A HR+P+++ +P KF PERFS++NK NI P+ Y PFG GPRNCIG RFAL +K+ +
Sbjct: 399 YALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIR 458
Query: 221 LLQHMEISPCEKTCIPSKLS 162
+LQ+ PC++T IP KLS
Sbjct: 459 VLQNFSFKPCKETQIPLKLS 478
>DQ924960-1|ABI96208.1| 503|Homo sapiens cytochrome P450 family 3
subfamily A polypeptide 4 protein.
Length = 503
Score = 135 bits (327), Expect = 9e-32
Identities = 64/140 (45%), Positives = 92/140 (65%)
Frame = -3
Query: 581 YNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPV 402
Y+++ M YLDMVV+E LRL+P + ++R+C +D + + KG V IP
Sbjct: 347 YDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEIN--------GMFIPKGVVVMIPS 398
Query: 401 WAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQ 222
+A HR+P+++ +P KF PERFS++NK NI P+ Y PFG GPRNCIG RFAL +K+ +
Sbjct: 399 YALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIR 458
Query: 221 LLQHMEISPCEKTCIPSKLS 162
+LQ+ PC++T IP KLS
Sbjct: 459 VLQNFSFKPCKETQIPLKLS 478
>DQ005611-1|AAY16980.1| 503|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 4 protein.
Length = 503
Score = 135 bits (327), Expect = 9e-32
Identities = 64/140 (45%), Positives = 92/140 (65%)
Frame = -3
Query: 581 YNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPV 402
Y+++ M YLDMVV+E LRL+P + ++R+C +D + + KG V IP
Sbjct: 347 YDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEIN--------GMFIPKGVVVMIPS 398
Query: 401 WAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQ 222
+A HR+P+++ +P KF PERFS++NK NI P+ Y PFG GPRNCIG RFAL +K+ +
Sbjct: 399 YALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIR 458
Query: 221 LLQHMEISPCEKTCIPSKLS 162
+LQ+ PC++T IP KLS
Sbjct: 459 VLQNFSFKPCKETQIPLKLS 478
>BC101631-1|AAI01632.1| 503|Homo sapiens cytochrome P450, subfamily
IIIA, polypeptide 4 protein.
Length = 503
Score = 135 bits (327), Expect = 9e-32
Identities = 64/140 (45%), Positives = 92/140 (65%)
Frame = -3
Query: 581 YNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPV 402
Y+++ M YLDMVV+E LRL+P + ++R+C +D + + KG V IP
Sbjct: 347 YDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEIN--------GMFIPKGVVVMIPS 398
Query: 401 WAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQ 222
+A HR+P+++ +P KF PERFS++NK NI P+ Y PFG GPRNCIG RFAL +K+ +
Sbjct: 399 YALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIR 458
Query: 221 LLQHMEISPCEKTCIPSKLS 162
+LQ+ PC++T IP KLS
Sbjct: 459 VLQNFSFKPCKETQIPLKLS 478
>BC069418-1|AAH69418.1| 503|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 4 protein.
Length = 503
Score = 135 bits (327), Expect = 9e-32
Identities = 64/140 (45%), Positives = 92/140 (65%)
Frame = -3
Query: 581 YNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPV 402
Y+++ M YLDMVV+E LRL+P + ++R+C +D + + KG V IP
Sbjct: 347 YDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEIN--------GMFIPKGVVVMIPS 398
Query: 401 WAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQ 222
+A HR+P+++ +P KF PERFS++NK NI P+ Y PFG GPRNCIG RFAL +K+ +
Sbjct: 399 YALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIR 458
Query: 221 LLQHMEISPCEKTCIPSKLS 162
+LQ+ PC++T IP KLS
Sbjct: 459 VLQNFSFKPCKETQIPLKLS 478
>AJ563377-1|CAD91345.1| 353|Homo sapiens cytochrome P450 protein.
Length = 353
Score = 135 bits (327), Expect = 9e-32
Identities = 64/140 (45%), Positives = 92/140 (65%)
Frame = -3
Query: 581 YNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPV 402
Y+++ M YLDMVV+E LRL+P + ++R+C +D + + KG V IP
Sbjct: 197 YDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEIN--------GMFIPKGVVVMIPS 248
Query: 401 WAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQ 222
+A HR+P+++ +P KF PERFS++NK NI P+ Y PFG GPRNCIG RFAL +K+ +
Sbjct: 249 YALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIR 308
Query: 221 LLQHMEISPCEKTCIPSKLS 162
+LQ+ PC++T IP KLS
Sbjct: 309 VLQNFSFKPCKETQIPLKLS 328
>AJ563376-2|CAD91645.1| 430|Homo sapiens cytochrome P450 protein.
Length = 430
Score = 135 bits (327), Expect = 9e-32
Identities = 64/140 (45%), Positives = 92/140 (65%)
Frame = -3
Query: 581 YNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPV 402
Y+++ M YLDMVV+E LRL+P + ++R+C +D + + KG V IP
Sbjct: 274 YDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEIN--------GMFIPKGVVVMIPS 325
Query: 401 WAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQ 222
+A HR+P+++ +P KF PERFS++NK NI P+ Y PFG GPRNCIG RFAL +K+ +
Sbjct: 326 YALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIR 385
Query: 221 LLQHMEISPCEKTCIPSKLS 162
+LQ+ PC++T IP KLS
Sbjct: 386 VLQNFSFKPCKETQIPLKLS 405
>AJ563375-1|CAD91343.1| 503|Homo sapiens cytochrome P450 protein.
Length = 503
Score = 135 bits (327), Expect = 9e-32
Identities = 64/140 (45%), Positives = 92/140 (65%)
Frame = -3
Query: 581 YNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPV 402
Y+++ M YLDMVV+E LRL+P + ++R+C +D + + KG V IP
Sbjct: 347 YDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEIN--------GMFIPKGVVVMIPS 398
Query: 401 WAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQ 222
+A HR+P+++ +P KF PERFS++NK NI P+ Y PFG GPRNCIG RFAL +K+ +
Sbjct: 399 YALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIR 458
Query: 221 LLQHMEISPCEKTCIPSKLS 162
+LQ+ PC++T IP KLS
Sbjct: 459 VLQNFSFKPCKETQIPLKLS 478
>AF280107-2|AAG32290.1| 503|Homo sapiens cytochrome P450
polypeptide 4 protein.
Length = 503
Score = 135 bits (327), Expect = 9e-32
Identities = 64/140 (45%), Positives = 92/140 (65%)
Frame = -3
Query: 581 YNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPV 402
Y+++ M YLDMVV+E LRL+P + ++R+C +D + + KG V IP
Sbjct: 347 YDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEIN--------GMFIPKGVVVMIPS 398
Query: 401 WAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQ 222
+A HR+P+++ +P KF PERFS++NK NI P+ Y PFG GPRNCIG RFAL +K+ +
Sbjct: 399 YALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIR 458
Query: 221 LLQHMEISPCEKTCIPSKLS 162
+LQ+ PC++T IP KLS
Sbjct: 459 VLQNFSFKPCKETQIPLKLS 478
>AF209389-1|AAF21034.1| 503|Homo sapiens cytochrome P450 IIIA4
protein.
Length = 503
Score = 135 bits (327), Expect = 9e-32
Identities = 64/140 (45%), Positives = 92/140 (65%)
Frame = -3
Query: 581 YNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPV 402
Y+++ M YLDMVV+E LRL+P + ++R+C +D + + KG V IP
Sbjct: 347 YDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEIN--------GMFIPKGVVVMIPS 398
Query: 401 WAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQ 222
+A HR+P+++ +P KF PERFS++NK NI P+ Y PFG GPRNCIG RFAL +K+ +
Sbjct: 399 YALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIR 458
Query: 221 LLQHMEISPCEKTCIPSKLS 162
+LQ+ PC++T IP KLS
Sbjct: 459 VLQNFSFKPCKETQIPLKLS 478
>AF182273-1|AAF13598.1| 503|Homo sapiens cytochrome P450-3A4
protein.
Length = 503
Score = 135 bits (327), Expect = 9e-32
Identities = 64/140 (45%), Positives = 92/140 (65%)
Frame = -3
Query: 581 YNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPV 402
Y+++ M YLDMVV+E LRL+P + ++R+C +D + + KG V IP
Sbjct: 347 YDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEIN--------GMFIPKGVVVMIPS 398
Query: 401 WAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQ 222
+A HR+P+++ +P KF PERFS++NK NI P+ Y PFG GPRNCIG RFAL +K+ +
Sbjct: 399 YALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIR 458
Query: 221 LLQHMEISPCEKTCIPSKLS 162
+LQ+ PC++T IP KLS
Sbjct: 459 VLQNFSFKPCKETQIPLKLS 478
>M14096-1|AAA35744.1| 503|Homo sapiens protein ( Human cytochrome
P-450 nifedipine oxidase mRNA, complet cds. ).
Length = 503
Score = 135 bits (326), Expect = 1e-31
Identities = 64/140 (45%), Positives = 92/140 (65%)
Frame = -3
Query: 581 YNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPV 402
Y+++ M YLDMVV+E LRL+P + ++R+C +D + + KG V IP
Sbjct: 347 YDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEIN--------GMFIPKGWVVMIPS 398
Query: 401 WAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQ 222
+A HR+P+++ +P KF PERFS++NK NI P+ Y PFG GPRNCIG RFAL +K+ +
Sbjct: 399 YALHRDPKYWTEPEKFLPERFSKKNKDNIDPYTYTPFGSGPRNCIGMRFALMNMKLALIR 458
Query: 221 LLQHMEISPCEKTCIPSKLS 162
+LQ+ PC++T IP KLS
Sbjct: 459 VLQNFSFKPCKETQIPLKLS 478
>J04449-1|AAA35747.1| 502|Homo sapiens cytochrome P450 nifedipine
oxidase protein.
Length = 502
Score = 135 bits (326), Expect = 1e-31
Identities = 64/140 (45%), Positives = 92/140 (65%)
Frame = -3
Query: 581 YNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPV 402
Y+++ M YLDMVV+E LRL+P + ++R+C +D + + KG V IP
Sbjct: 346 YDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEIN--------GMFIPKGWVVMIPS 397
Query: 401 WAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQ 222
+A HR+P+++ +P KF PERFS++NK NI P+ Y PFG GPRNCIG RFAL +K+ +
Sbjct: 398 YALHRDPKYWTEPEKFLPERFSKKNKDNIDPYTYTPFGSGPRNCIGMRFALMNMKLALIR 457
Query: 221 LLQHMEISPCEKTCIPSKLS 162
+LQ+ PC++T IP KLS
Sbjct: 458 VLQNFSFKPCKETQIPLKLS 477
>X12387-1|CAA30944.1| 503|Homo sapiens protein ( Human mRNA for
cytochrome P-450 (cyp3 locus). ).
Length = 503
Score = 134 bits (325), Expect = 2e-31
Identities = 64/140 (45%), Positives = 92/140 (65%)
Frame = -3
Query: 581 YNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPV 402
Y+++ M YLDMVV+E LRL+P + ++R+C +D + + KG V IP
Sbjct: 347 YDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEIN--------GMFIPKGWVVMIPS 398
Query: 401 WAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQ 222
+A HR+P+++ +P KF PERFS++NK NI P+ Y PFG GPRNCIG RFAL +K+ +
Sbjct: 399 YALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIR 458
Query: 221 LLQHMEISPCEKTCIPSKLS 162
+LQ+ PC++T IP KLS
Sbjct: 459 VLQNFSFKPCKETQIPLKLS 478
>M13785-1|AAA35742.1| 504|Homo sapiens protein ( Human liver
glucocorticoid-inducible cytochrome P-450 (HLp) mRNA,
complete cds. ).
Length = 504
Score = 134 bits (325), Expect = 2e-31
Identities = 64/140 (45%), Positives = 92/140 (65%)
Frame = -3
Query: 581 YNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPV 402
Y+++ M YLDMVV+E LRL+P + ++R+C +D + + KG V IP
Sbjct: 348 YDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEIN--------GMFIPKGWVVMIPS 399
Query: 401 WAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQ 222
+A HR+P+++ +P KF PERFS++NK NI P+ Y PFG GPRNCIG RFAL +K+ +
Sbjct: 400 YALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIR 459
Query: 221 LLQHMEISPCEKTCIPSKLS 162
+LQ+ PC++T IP KLS
Sbjct: 460 VLQNFSFKPCKETQIPLKLS 479
>D00003-1|BAA00001.1| 504|Homo sapiens cytochrome P-450 protein.
Length = 504
Score = 134 bits (325), Expect = 2e-31
Identities = 64/140 (45%), Positives = 92/140 (65%)
Frame = -3
Query: 581 YNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPV 402
Y+++ M YLDMVV+E LRL+P + ++R+C +D + + KG V IP
Sbjct: 348 YDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEIN--------GMFIPKGWVVMIPS 399
Query: 401 WAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQ 222
+A HR+P+++ +P KF PERFS++NK NI P+ Y PFG GPRNCIG RFAL +K+ +
Sbjct: 400 YALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIR 459
Query: 221 LLQHMEISPCEKTCIPSKLS 162
+LQ+ PC++T IP KLS
Sbjct: 460 VLQNFSFKPCKETQIPLKLS 479
>D00408-1|BAA00310.1| 503|Homo sapiens cytochrome P-450 HFLa
protein.
Length = 503
Score = 129 bits (312), Expect = 6e-30
Identities = 60/139 (43%), Positives = 89/139 (64%)
Frame = -3
Query: 581 YNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPV 402
Y+++ + YLDMVV+E LRL+P + ++R+C +D + + KG V IP
Sbjct: 347 YDTVLQLEYLDMVVNETLRLFPVAMRLERVCKKDVEIN--------GMFIPKGVVVMIPS 398
Query: 401 WAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQ 222
+ H +P+++ +P KF PERFS++NK NI P+ Y PFG GPRNCIG RFAL +K+ +
Sbjct: 399 YVLHHDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALVNMKLALVR 458
Query: 221 LLQHMEISPCEKTCIPSKL 165
+LQ+ PC++T IP KL
Sbjct: 459 VLQNFSFKPCKETQIPLKL 477
>BC067436-1|AAH67436.1| 503|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 7 protein.
Length = 503
Score = 129 bits (312), Expect = 6e-30
Identities = 60/139 (43%), Positives = 89/139 (64%)
Frame = -3
Query: 581 YNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPV 402
Y+++ + YLDMVV+E LRL+P + ++R+C +D + + KG V IP
Sbjct: 347 YDTVLQLEYLDMVVNETLRLFPVAMRLERVCKKDVEIN--------GMFIPKGVVVMIPS 398
Query: 401 WAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQ 222
+ H +P+++ +P KF PERFS++NK NI P+ Y PFG GPRNCIG RFAL +K+ +
Sbjct: 399 YVLHHDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALVNMKLALVR 458
Query: 221 LLQHMEISPCEKTCIPSKL 165
+LQ+ PC++T IP KL
Sbjct: 459 VLQNFSFKPCKETQIPLKL 477
>AF315325-1|AAG48618.1| 535|Homo sapiens cytochrome P450 variant
3A7 protein.
Length = 535
Score = 129 bits (312), Expect = 6e-30
Identities = 60/139 (43%), Positives = 89/139 (64%)
Frame = -3
Query: 581 YNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPV 402
Y+++ + YLDMVV+E LRL+P + ++R+C +D + + KG V IP
Sbjct: 347 YDTVLQLEYLDMVVNETLRLFPVAMRLERVCKKDVEIN--------GMFIPKGVVVMIPS 398
Query: 401 WAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQ 222
+ H +P+++ +P KF PERFS++NK NI P+ Y PFG GPRNCIG RFAL +K+ +
Sbjct: 399 YVLHHDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALVNMKLALVR 458
Query: 221 LLQHMEISPCEKTCIPSKL 165
+LQ+ PC++T IP KL
Sbjct: 459 VLQNFSFKPCKETQIPLKL 477
>AF280107-3|AAG32289.1| 503|Homo sapiens cytochrome P450
polypeptide 7 protein.
Length = 503
Score = 129 bits (312), Expect = 6e-30
Identities = 60/139 (43%), Positives = 89/139 (64%)
Frame = -3
Query: 581 YNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPV 402
Y+++ + YLDMVV+E LRL+P + ++R+C +D + + KG V IP
Sbjct: 347 YDTVLQLEYLDMVVNETLRLFPVAMRLERVCKKDVEIN--------GMFIPKGVVVMIPS 398
Query: 401 WAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQ 222
+ H +P+++ +P KF PERFS++NK NI P+ Y PFG GPRNCIG RFAL +K+ +
Sbjct: 399 YVLHHDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALVNMKLALVR 458
Query: 221 LLQHMEISPCEKTCIPSKL 165
+LQ+ PC++T IP KL
Sbjct: 459 VLQNFSFKPCKETQIPLKL 477
>BC100981-1|AAI00982.1| 393|Homo sapiens CYP3A43 protein protein.
Length = 393
Score = 126 bits (305), Expect = 4e-29
Identities = 59/139 (42%), Positives = 88/139 (63%)
Frame = -3
Query: 581 YNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPV 402
Y+++ M YLDMVV+E LRL+P + R+C +D + + KG V +P+
Sbjct: 237 YDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEIN--------GVFIPKGLAVMVPI 288
Query: 401 WAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQ 222
+A H +P+++ +P KF PERFS++NK +I + Y+PFG GPRNCIG RFAL +K+ +
Sbjct: 289 YALHHDPKYWTEPEKFCPERFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIR 348
Query: 221 LLQHMEISPCEKTCIPSKL 165
LQ+ PC++T IP KL
Sbjct: 349 ALQNFSFKPCKETQIPLKL 367
>AY390425-1|AAQ92353.1| 503|Homo sapiens cytochrome P450 CYP3A43.1
protein.
Length = 503
Score = 126 bits (305), Expect = 4e-29
Identities = 59/139 (42%), Positives = 88/139 (63%)
Frame = -3
Query: 581 YNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPV 402
Y+++ M YLDMVV+E LRL+P + R+C +D + + KG V +P+
Sbjct: 347 YDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEIN--------GVFIPKGLAVMVPI 398
Query: 401 WAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQ 222
+A H +P+++ +P KF PERFS++NK +I + Y+PFG GPRNCIG RFAL +K+ +
Sbjct: 399 YALHHDPKYWTEPEKFCPERFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIR 458
Query: 221 LLQHMEISPCEKTCIPSKL 165
LQ+ PC++T IP KL
Sbjct: 459 ALQNFSFKPCKETQIPLKL 477
>AY390424-1|AAQ92352.1| 503|Homo sapiens cytochrome P450 CYP3A43.3
protein.
Length = 503
Score = 126 bits (305), Expect = 4e-29
Identities = 59/139 (42%), Positives = 88/139 (63%)
Frame = -3
Query: 581 YNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPV 402
Y+++ M YLDMVV+E LRL+P + R+C +D + + KG V +P+
Sbjct: 347 YDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEIN--------GVFIPKGLAVMVPI 398
Query: 401 WAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQ 222
+A H +P+++ +P KF PERFS++NK +I + Y+PFG GPRNCIG RFAL +K+ +
Sbjct: 399 YALHHDPKYWTEPEKFCPERFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIR 458
Query: 221 LLQHMEISPCEKTCIPSKL 165
LQ+ PC++T IP KL
Sbjct: 459 ALQNFSFKPCKETQIPLKL 477
>AF337813-1|AAK38841.1| 503|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 503
Score = 126 bits (305), Expect = 4e-29
Identities = 59/139 (42%), Positives = 88/139 (63%)
Frame = -3
Query: 581 YNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPV 402
Y+++ M YLDMVV+E LRL+P + R+C +D + + KG V +P+
Sbjct: 347 YDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEIN--------GVFIPKGLAVMVPI 398
Query: 401 WAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQ 222
+A H +P+++ +P KF PERFS++NK +I + Y+PFG GPRNCIG RFAL +K+ +
Sbjct: 399 YALHHDPKYWTEPEKFCPERFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIR 458
Query: 221 LLQHMEISPCEKTCIPSKL 165
LQ+ PC++T IP KL
Sbjct: 459 ALQNFSFKPCKETQIPLKL 477
>AF319634-1|AAK00325.1| 503|Homo sapiens cytochrome P450 CYP3A43
protein.
Length = 503
Score = 126 bits (305), Expect = 4e-29
Identities = 59/139 (42%), Positives = 88/139 (63%)
Frame = -3
Query: 581 YNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPV 402
Y+++ M YLDMVV+E LRL+P + R+C +D + + KG V +P+
Sbjct: 347 YDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEIN--------GVFIPKGLAVMVPI 398
Query: 401 WAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQ 222
+A H +P+++ +P KF PERFS++NK +I + Y+PFG GPRNCIG RFAL +K+ +
Sbjct: 399 YALHHDPKYWTEPEKFCPERFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIR 458
Query: 221 LLQHMEISPCEKTCIPSKL 165
LQ+ PC++T IP KL
Sbjct: 459 ALQNFSFKPCKETQIPLKL 477
>AF280108-1|AAG33009.1| 503|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 503
Score = 126 bits (305), Expect = 4e-29
Identities = 59/139 (42%), Positives = 88/139 (63%)
Frame = -3
Query: 581 YNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPV 402
Y+++ M YLDMVV+E LRL+P + R+C +D + + KG V +P+
Sbjct: 347 YDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEIN--------GVFIPKGLAVMVPI 398
Query: 401 WAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQ 222
+A H +P+++ +P KF PERFS++NK +I + Y+PFG GPRNCIG RFAL +K+ +
Sbjct: 399 YALHHDPKYWTEPEKFCPERFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIR 458
Query: 221 LLQHMEISPCEKTCIPSKL 165
LQ+ PC++T IP KL
Sbjct: 459 ALQNFSFKPCKETQIPLKL 477
>AC011904-4|AAS07395.1| 503|Homo sapiens unknown protein.
Length = 503
Score = 126 bits (305), Expect = 4e-29
Identities = 59/139 (42%), Positives = 88/139 (63%)
Frame = -3
Query: 581 YNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPV 402
Y+++ M YLDMVV+E LRL+P + R+C +D + + KG V +P+
Sbjct: 347 YDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEIN--------GVFIPKGLAVMVPI 398
Query: 401 WAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQ 222
+A H +P+++ +P KF PERFS++NK +I + Y+PFG GPRNCIG RFAL +K+ +
Sbjct: 399 YALHHDPKYWTEPEKFCPERFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIR 458
Query: 221 LLQHMEISPCEKTCIPSKL 165
LQ+ PC++T IP KL
Sbjct: 459 ALQNFSFKPCKETQIPLKL 477
>AK223008-1|BAD96728.1| 502|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 5 variant protein.
Length = 502
Score = 125 bits (302), Expect = 1e-28
Identities = 59/142 (41%), Positives = 91/142 (64%)
Frame = -3
Query: 581 YNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPV 402
Y+++ M YLDMVV+E LRL+P + ++R C++D + + KG+ V IP
Sbjct: 347 YDAVVQMEYLDMVVNETLRLFPVAIRLERTCMKDVEIN--------GVFIPKGSMVVIPT 398
Query: 401 WAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQ 222
+A H +P+++ +P +F PERFS++ K +I P+ Y PFG GPRNCIG RFAL +K+ +
Sbjct: 399 YALHHDPKYWTEPEEFRPERFSKK-KDSIDPYIYTPFGTGPRNCIGMRFALMNMKLALIR 457
Query: 221 LLQHMEISPCEKTCIPSKLSKE 156
+LQ+ PC++T IP KL +
Sbjct: 458 VLQNFSFKPCKETQIPLKLDTQ 479
>J04813-1|AAA02993.1| 502|Homo sapiens cytochrome P450 PCN3
protein.
Length = 502
Score = 124 bits (299), Expect = 2e-28
Identities = 59/142 (41%), Positives = 90/142 (63%)
Frame = -3
Query: 581 YNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPV 402
Y+++ M YLDMVV+E LRL+P + ++R C +D + + KG+ V IP
Sbjct: 347 YDAVVQMEYLDMVVNETLRLFPVAIRLERTCKKDVEIN--------GVFIPKGSMVVIPT 398
Query: 401 WAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQ 222
+A H +P+++ +P +F PERFS++ K +I P+ Y PFG GPRNCIG RFAL +K+ +
Sbjct: 399 YALHHDPKYWTEPEEFRPERFSKK-KDSIDPYIYTPFGTGPRNCIGMRFALMNMKLALIR 457
Query: 221 LLQHMEISPCEKTCIPSKLSKE 156
+LQ+ PC++T IP KL +
Sbjct: 458 VLQNFSFKPCKETQIPLKLDTQ 479
>BC033862-1|AAH33862.1| 502|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 5 protein.
Length = 502
Score = 124 bits (299), Expect = 2e-28
Identities = 59/142 (41%), Positives = 90/142 (63%)
Frame = -3
Query: 581 YNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPV 402
Y+++ M YLDMVV+E LRL+P + ++R C +D + + KG+ V IP
Sbjct: 347 YDAVVQMEYLDMVVNETLRLFPVAIRLERTCKKDVEIN--------GVFIPKGSMVVIPT 398
Query: 401 WAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQ 222
+A H +P+++ +P +F PERFS++ K +I P+ Y PFG GPRNCIG RFAL +K+ +
Sbjct: 399 YALHHDPKYWTEPEEFRPERFSKK-KDSIDPYIYTPFGTGPRNCIGMRFALMNMKLALIR 457
Query: 221 LLQHMEISPCEKTCIPSKLSKE 156
+LQ+ PC++T IP KL +
Sbjct: 458 VLQNFSFKPCKETQIPLKLDTQ 479
>AJ563378-3|CAD91347.1| 173|Homo sapiens hypothetical protein
protein.
Length = 173
Score = 124 bits (299), Expect = 2e-28
Identities = 59/142 (41%), Positives = 90/142 (63%)
Frame = -3
Query: 581 YNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPV 402
Y+++ M YLDMVV+E LRL+P + ++R C +D + + KG+ V IP
Sbjct: 18 YDAVVQMEYLDMVVNETLRLFPVAIRLERTCKKDVEIN--------GVFIPKGSMVVIPT 69
Query: 401 WAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQ 222
+A H +P+++ +P +F PERFS++ K +I P+ Y PFG GPRNCIG RFAL +K+ +
Sbjct: 70 YALHHDPKYWTEPEEFRPERFSKK-KDSIDPYIYTPFGTGPRNCIGMRFALMNMKLALIR 128
Query: 221 LLQHMEISPCEKTCIPSKLSKE 156
+LQ+ PC++T IP KL +
Sbjct: 129 VLQNFSFKPCKETQIPLKLDTQ 150
>AJ563378-2|CAD91647.1| 160|Homo sapiens cytochrome P450 protein.
Length = 160
Score = 124 bits (299), Expect = 2e-28
Identities = 59/142 (41%), Positives = 90/142 (63%)
Frame = -3
Query: 581 YNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPV 402
Y+++ M YLDMVV+E LRL+P + ++R C +D + + KG+ V IP
Sbjct: 5 YDAVVQMEYLDMVVNETLRLFPVAIRLERTCKKDVEIN--------GVFIPKGSMVVIPT 56
Query: 401 WAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQ 222
+A H +P+++ +P +F PERFS++ K +I P+ Y PFG GPRNCIG RFAL +K+ +
Sbjct: 57 YALHHDPKYWTEPEEFRPERFSKK-KDSIDPYIYTPFGTGPRNCIGMRFALMNMKLALIR 115
Query: 221 LLQHMEISPCEKTCIPSKLSKE 156
+LQ+ PC++T IP KL +
Sbjct: 116 VLQNFSFKPCKETQIPLKLDTQ 137
>AC005020-1|AAS02016.1| 502|Homo sapiens unknown protein.
Length = 502
Score = 124 bits (299), Expect = 2e-28
Identities = 59/142 (41%), Positives = 90/142 (63%)
Frame = -3
Query: 581 YNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPV 402
Y+++ M YLDMVV+E LRL+P + ++R C +D + + KG+ V IP
Sbjct: 347 YDAVVQMEYLDMVVNETLRLFPVAIRLERTCKKDVEIN--------GVFIPKGSMVVIPT 398
Query: 401 WAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQ 222
+A H +P+++ +P +F PERFS++ K +I P+ Y PFG GPRNCIG RFAL +K+ +
Sbjct: 399 YALHHDPKYWTEPEEFRPERFSKK-KDSIDPYIYTPFGTGPRNCIGMRFALMNMKLALIR 457
Query: 221 LLQHMEISPCEKTCIPSKLSKE 156
+LQ+ PC++T IP KL +
Sbjct: 458 VLQNFSFKPCKETQIPLKLDTQ 479
>AF280109-1|AAG33010.1| 504|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 504
Score = 122 bits (294), Expect = 9e-28
Identities = 59/140 (42%), Positives = 88/140 (62%), Gaps = 1/140 (0%)
Frame = -3
Query: 581 YNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPV 402
Y+++ M YLDMVV+E LRL+P + R+C +D + + KG V +P+
Sbjct: 347 YDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEIN--------GVFIPKGLAVMVPI 398
Query: 401 WAFHRNPEFFPDPLKFDPE-RFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAY 225
+A H +P+++ +P KF PE RFS++NK +I + Y+PFG GPRNCIG RFAL +K+
Sbjct: 399 YALHHDPKYWTEPEKFCPESRFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVI 458
Query: 224 QLLQHMEISPCEKTCIPSKL 165
+ LQ+ PC++T IP KL
Sbjct: 459 RALQNFSFKPCKETQIPLKL 478
>AC011904-5|AAS07394.1| 504|Homo sapiens unknown protein.
Length = 504
Score = 122 bits (294), Expect = 9e-28
Identities = 59/140 (42%), Positives = 88/140 (62%), Gaps = 1/140 (0%)
Frame = -3
Query: 581 YNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPV 402
Y+++ M YLDMVV+E LRL+P + R+C +D + + KG V +P+
Sbjct: 347 YDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEIN--------GVFIPKGLAVMVPI 398
Query: 401 WAFHRNPEFFPDPLKFDPE-RFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAY 225
+A H +P+++ +P KF PE RFS++NK +I + Y+PFG GPRNCIG RFAL +K+
Sbjct: 399 YALHHDPKYWTEPEKFCPESRFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVI 458
Query: 224 QLLQHMEISPCEKTCIPSKL 165
+ LQ+ PC++T IP KL
Sbjct: 459 RALQNFSFKPCKETQIPLKL 478
>AF236085-1|AAG15889.1| 524|Homo sapiens CYP4F11 protein.
Length = 524
Score = 105 bits (251), Expect = 2e-22
Identities = 59/158 (37%), Positives = 85/158 (53%)
Frame = -3
Query: 584 DYNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIP 405
+++ + + +L M + E LRL PP + R C QD+ L P+ + + KG I
Sbjct: 371 EWDDLAQLPFLTMCIKESLRLHPPVPVISRCCTQDFVL--PDGRV-----IPKGIVCLIN 423
Query: 404 VWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAY 225
+ H NP +PDP +DP RF++EN P A++PF GPRNCIG FA+ E+KV+
Sbjct: 424 IIGIHYNPTVWPDPEVYDPFRFNQENIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLA 483
Query: 224 QLLQHMEISPCEKTCIPSKLSKETFNLRLEGGHWVRLK 111
L H I P T I + E LR EGG W+R++
Sbjct: 484 LTLLHFRILP---THIEPRRKPELI-LRAEGGLWLRVE 517
>BC016853-1|AAH16853.1| 524|Homo sapiens CYP4F11 protein protein.
Length = 524
Score = 104 bits (249), Expect = 3e-22
Identities = 58/158 (36%), Positives = 84/158 (53%)
Frame = -3
Query: 584 DYNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIP 405
+++ + + +L M + E LRL PP + R C QD+ L P+ + + KG I
Sbjct: 371 EWDDLAQLPFLTMCIKESLRLHPPVPVISRCCTQDFVL--PDGRV-----IPKGIVCLIN 423
Query: 404 VWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAY 225
+ H NP +PDP +DP RF++EN P A++PF GPRNCIG FA+ E+KV+
Sbjct: 424 IIGIHYNPTVWPDPEVYDPFRFNQENIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLA 483
Query: 224 QLLQHMEISPCEKTCIPSKLSKETFNLRLEGGHWVRLK 111
L H I P P + K LR EGG W+R++
Sbjct: 484 LTLLHFRILPTHTE--PRR--KPELILRAEGGLWLRVE 517
>BC035350-1|AAH35350.1| 524|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 12 protein.
Length = 524
Score = 102 bits (245), Expect = 8e-22
Identities = 58/158 (36%), Positives = 82/158 (51%)
Frame = -3
Query: 584 DYNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIP 405
+++ + + +L M V E LRL PP + R C QD L P+ + + KG I
Sbjct: 371 EWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDIVL--PDGRV-----IPKGITCLID 423
Query: 404 VWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAY 225
+ H NP +PDP +DP RF EN P A++PF GPRNCIG FA+ E+KV+
Sbjct: 424 IIGVHHNPTVWPDPEVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLA 483
Query: 224 QLLQHMEISPCEKTCIPSKLSKETFNLRLEGGHWVRLK 111
+L H P + T KL +R EGG W+R++
Sbjct: 484 LMLLHFRFLP-DHTEPRRKLE---LIMRAEGGLWLRVE 517
>AY358977-1|AAQ89336.1| 524|Homo sapiens CYP4F12 protein.
Length = 524
Score = 102 bits (245), Expect = 8e-22
Identities = 58/158 (36%), Positives = 82/158 (51%)
Frame = -3
Query: 584 DYNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIP 405
+++ + + +L M V E LRL PP + R C QD L P+ + + KG I
Sbjct: 371 EWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDIVL--PDGRV-----IPKGITCLID 423
Query: 404 VWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAY 225
+ H NP +PDP +DP RF EN P A++PF GPRNCIG FA+ E+KV+
Sbjct: 424 IIGVHHNPTVWPDPEVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLA 483
Query: 224 QLLQHMEISPCEKTCIPSKLSKETFNLRLEGGHWVRLK 111
+L H P + T KL +R EGG W+R++
Sbjct: 484 LMLLHFRFLP-DHTEPRRKLE---LIMRAEGGLWLRVE 517
>AY008841-1|AAG33247.1| 524|Homo sapiens cytochrome P450 isoform
4F12 protein.
Length = 524
Score = 102 bits (245), Expect = 8e-22
Identities = 58/158 (36%), Positives = 82/158 (51%)
Frame = -3
Query: 584 DYNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIP 405
+++ + + +L M V E LRL PP + R C QD L P+ + + KG I
Sbjct: 371 EWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDIVL--PDGRV-----IPKGITCLID 423
Query: 404 VWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAY 225
+ H NP +PDP +DP RF EN P A++PF GPRNCIG FA+ E+KV+
Sbjct: 424 IIGVHHNPTVWPDPEVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLA 483
Query: 224 QLLQHMEISPCEKTCIPSKLSKETFNLRLEGGHWVRLK 111
+L H P + T KL +R EGG W+R++
Sbjct: 484 LMLLHFRFLP-DHTEPRRKLE---LIMRAEGGLWLRVE 517
>AC004523-1|AAC11543.1| 458|Homo sapiens F22329_1 protein.
Length = 458
Score = 102 bits (245), Expect = 8e-22
Identities = 58/158 (36%), Positives = 82/158 (51%)
Frame = -3
Query: 584 DYNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIP 405
+++ + + +L M V E LRL PP + R C QD L P+ + + KG I
Sbjct: 305 EWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDIVL--PDGRV-----IPKGITCLID 357
Query: 404 VWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAY 225
+ H NP +PDP +DP RF EN P A++PF GPRNCIG FA+ E+KV+
Sbjct: 358 IIGVHHNPTVWPDPEVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLA 417
Query: 224 QLLQHMEISPCEKTCIPSKLSKETFNLRLEGGHWVRLK 111
+L H P + T KL +R EGG W+R++
Sbjct: 418 LMLLHFRFLP-DHTEPRRKLE---LIMRAEGGLWLRVE 451
>AB035131-1|BAB18270.1| 524|Homo sapiens cytochrome P450 protein.
Length = 524
Score = 102 bits (245), Expect = 8e-22
Identities = 58/158 (36%), Positives = 82/158 (51%)
Frame = -3
Query: 584 DYNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIP 405
+++ + + +L M V E LRL PP + R C QD L P+ + + KG I
Sbjct: 371 EWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDIVL--PDGRV-----IPKGITCLID 423
Query: 404 VWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAY 225
+ H NP +PDP +DP RF EN P A++PF GPRNCIG FA+ E+KV+
Sbjct: 424 IIGVHHNPTVWPDPEVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLA 483
Query: 224 QLLQHMEISPCEKTCIPSKLSKETFNLRLEGGHWVRLK 111
+L H P + T KL +R EGG W+R++
Sbjct: 484 LMLLHFRFLP-DHTEPRRKLE---LIMRAEGGLWLRVE 517
>AB035130-1|BAB18269.1| 524|Homo sapiens cytochrome P450 protein.
Length = 524
Score = 102 bits (245), Expect = 8e-22
Identities = 58/158 (36%), Positives = 82/158 (51%)
Frame = -3
Query: 584 DYNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIP 405
+++ + + +L M V E LRL PP + R C QD L P+ + + KG I
Sbjct: 371 EWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDIVL--PDGRV-----IPKGITCLID 423
Query: 404 VWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAY 225
+ H NP +PDP +DP RF EN P A++PF GPRNCIG FA+ E+KV+
Sbjct: 424 IIGVHHNPTVWPDPEVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLA 483
Query: 224 QLLQHMEISPCEKTCIPSKLSKETFNLRLEGGHWVRLK 111
+L H P + T KL +R EGG W+R++
Sbjct: 484 LMLLHFRFLP-DHTEPRRKLE---LIMRAEGGLWLRVE 517
>AF233624-1|AAF99278.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 101 bits (243), Expect = 1e-21
Identities = 51/140 (36%), Positives = 76/140 (54%), Gaps = 1/140 (0%)
Frame = -3
Query: 569 QNMVYLDMVVSELLRLWPPGVSMDRICVQDYN-LGKPNDKAKRDFTLRKGTGVAIPVWAF 393
+ + YLDMV++E LR++PP R QD LG+ + G + + V A
Sbjct: 389 EGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQ---------RIPAGAVLEMAVGAL 439
Query: 392 HRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQLLQ 213
H +PE +P P F+PERF+ E + +PF YLPFG GPR+C+G R L EVK+ +L
Sbjct: 440 HHDPEHWPSPENFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLH 499
Query: 212 HMEISPCEKTCIPSKLSKET 153
C +T +P +L ++
Sbjct: 500 KFRFQACPETQVPLQLESKS 519
>AF233623-1|AAF99277.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 101 bits (243), Expect = 1e-21
Identities = 51/140 (36%), Positives = 76/140 (54%), Gaps = 1/140 (0%)
Frame = -3
Query: 569 QNMVYLDMVVSELLRLWPPGVSMDRICVQDYN-LGKPNDKAKRDFTLRKGTGVAIPVWAF 393
+ + YLDMV++E LR++PP R QD LG+ + G + + V A
Sbjct: 389 EGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQ---------RIPAGAVLEMAVGAL 439
Query: 392 HRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQLLQ 213
H +PE +P P F+PERF+ E + +PF YLPFG GPR+C+G R L EVK+ +L
Sbjct: 440 HHDPEHWPSPKTFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLH 499
Query: 212 HMEISPCEKTCIPSKLSKET 153
C +T +P +L ++
Sbjct: 500 KFRFQACPETQVPLQLESKS 519
>M80647-1|AAA60618.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 101 bits (242), Expect = 2e-21
Identities = 51/140 (36%), Positives = 76/140 (54%), Gaps = 1/140 (0%)
Frame = -3
Query: 569 QNMVYLDMVVSELLRLWPPGVSMDRICVQDYN-LGKPNDKAKRDFTLRKGTGVAIPVWAF 393
+ + YLDMV++E LR++PP R QD LG+ + G + + V A
Sbjct: 389 EGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQ---------RIPAGAVLEMAVGAL 439
Query: 392 HRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQLLQ 213
H +PE +P P F+PERF+ E + +PF YLPFG GPR+C+G R L EVK+ +L
Sbjct: 440 HHDPEHWPSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLH 499
Query: 212 HMEISPCEKTCIPSKLSKET 153
C +T +P +L ++
Sbjct: 500 KFRFQACPETQVPLQLESKS 519
>BC041157-1|AAH41157.1| 534|Homo sapiens thromboxane A synthase 1
(platelet, cytochrome P450, family 5, subfamily A)
protein.
Length = 534
Score = 101 bits (242), Expect = 2e-21
Identities = 51/140 (36%), Positives = 76/140 (54%), Gaps = 1/140 (0%)
Frame = -3
Query: 569 QNMVYLDMVVSELLRLWPPGVSMDRICVQDYN-LGKPNDKAKRDFTLRKGTGVAIPVWAF 393
+ + YLDMV++E LR++PP R QD LG+ + G + + V A
Sbjct: 389 EGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQ---------RIPAGAVLEMAVGAL 439
Query: 392 HRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQLLQ 213
H +PE +P P F+PERF+ E + +PF YLPFG GPR+C+G R L EVK+ +L
Sbjct: 440 HHDPEHWPSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLH 499
Query: 212 HMEISPCEKTCIPSKLSKET 153
C +T +P +L ++
Sbjct: 500 KFRFQACPETQVPLQLESKS 519
>BC014117-1|AAH14117.1| 466|Homo sapiens TBXAS1 protein protein.
Length = 466
Score = 101 bits (242), Expect = 2e-21
Identities = 51/140 (36%), Positives = 76/140 (54%), Gaps = 1/140 (0%)
Frame = -3
Query: 569 QNMVYLDMVVSELLRLWPPGVSMDRICVQDYN-LGKPNDKAKRDFTLRKGTGVAIPVWAF 393
+ + YLDMV++E LR++PP R QD LG+ + G + + V A
Sbjct: 321 EGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQ---------RIPAGAVLEMAVGAL 371
Query: 392 HRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQLLQ 213
H +PE +P P F+PERF+ E + +PF YLPFG GPR+C+G R L EVK+ +L
Sbjct: 372 HHDPEHWPSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLH 431
Query: 212 HMEISPCEKTCIPSKLSKET 153
C +T +P +L ++
Sbjct: 432 KFRFQACPETQVPLQLESKS 451
>AK223466-1|BAD97186.1| 534|Homo sapiens thromboxane A synthase 1
(platelet, cytochrome P450, family 5, subfamily A) iso
protein.
Length = 534
Score = 101 bits (242), Expect = 2e-21
Identities = 51/140 (36%), Positives = 76/140 (54%), Gaps = 1/140 (0%)
Frame = -3
Query: 569 QNMVYLDMVVSELLRLWPPGVSMDRICVQDYN-LGKPNDKAKRDFTLRKGTGVAIPVWAF 393
+ + YLDMV++E LR++PP R QD LG+ + G + + V A
Sbjct: 389 EGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQ---------RIPAGAVLEMAVGAL 439
Query: 392 HRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQLLQ 213
H +PE +P P F+PERF+ E + +PF YLPFG GPR+C+G R L EVK+ +L
Sbjct: 440 HHDPEHWPSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLH 499
Query: 212 HMEISPCEKTCIPSKLSKET 153
C +T +P +L ++
Sbjct: 500 KFRFQACPETQVPLQLESKS 519
>AF233621-1|AAF99275.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 101 bits (242), Expect = 2e-21
Identities = 51/140 (36%), Positives = 76/140 (54%), Gaps = 1/140 (0%)
Frame = -3
Query: 569 QNMVYLDMVVSELLRLWPPGVSMDRICVQDYN-LGKPNDKAKRDFTLRKGTGVAIPVWAF 393
+ + YLDMV++E LR++PP R QD LG+ + G + + V A
Sbjct: 389 EGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQ---------RIPAGAVLEMAVGAL 439
Query: 392 HRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQLLQ 213
H +PE +P P F+PERF+ E + +PF YLPFG GPR+C+G R L EVK+ +L
Sbjct: 440 HHDPEHWPSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLH 499
Query: 212 HMEISPCEKTCIPSKLSKET 153
C +T +P +L ++
Sbjct: 500 KFRFQACPETQVPLQLESKS 519
>AF233620-1|AAF99274.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 101 bits (242), Expect = 2e-21
Identities = 51/140 (36%), Positives = 76/140 (54%), Gaps = 1/140 (0%)
Frame = -3
Query: 569 QNMVYLDMVVSELLRLWPPGVSMDRICVQDYN-LGKPNDKAKRDFTLRKGTGVAIPVWAF 393
+ + YLDMV++E LR++PP R QD LG+ + G + + V A
Sbjct: 389 EGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQ---------RIPAGAVLEMAVGAL 439
Query: 392 HRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQLLQ 213
H +PE +P P F+PERF+ E + +PF YLPFG GPR+C+G R L EVK+ +L
Sbjct: 440 HHDPEHWPSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLH 499
Query: 212 HMEISPCEKTCIPSKLSKET 153
C +T +P +L ++
Sbjct: 500 KFRFQACPETQVPLQLESKS 519
>AF233619-1|AAF99273.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 101 bits (242), Expect = 2e-21
Identities = 51/140 (36%), Positives = 76/140 (54%), Gaps = 1/140 (0%)
Frame = -3
Query: 569 QNMVYLDMVVSELLRLWPPGVSMDRICVQDYN-LGKPNDKAKRDFTLRKGTGVAIPVWAF 393
+ + YLDMV++E LR++PP R QD LG+ + G + + V A
Sbjct: 389 EGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQ---------RIPAGAVLEMAVGAL 439
Query: 392 HRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQLLQ 213
H +PE +P P F+PERF+ E + +PF YLPFG GPR+C+G R L EVK+ +L
Sbjct: 440 HHDPEHWPSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLH 499
Query: 212 HMEISPCEKTCIPSKLSKET 153
C +T +P +L ++
Sbjct: 500 KFRFQACPETQVPLQLESKS 519
>AF233618-1|AAF99272.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 101 bits (242), Expect = 2e-21
Identities = 51/140 (36%), Positives = 76/140 (54%), Gaps = 1/140 (0%)
Frame = -3
Query: 569 QNMVYLDMVVSELLRLWPPGVSMDRICVQDYN-LGKPNDKAKRDFTLRKGTGVAIPVWAF 393
+ + YLDMV++E LR++PP R QD LG+ + G + + V A
Sbjct: 389 EGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQ---------RIPAGAVLEMAVGAL 439
Query: 392 HRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQLLQ 213
H +PE +P P F+PERF+ E + +PF YLPFG GPR+C+G R L EVK+ +L
Sbjct: 440 HHDPEHWPSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLH 499
Query: 212 HMEISPCEKTCIPSKLSKET 153
C +T +P +L ++
Sbjct: 500 KFRFQACPETQVPLQLESKS 519
>AF233617-1|AAF99271.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 101 bits (242), Expect = 2e-21
Identities = 51/140 (36%), Positives = 76/140 (54%), Gaps = 1/140 (0%)
Frame = -3
Query: 569 QNMVYLDMVVSELLRLWPPGVSMDRICVQDYN-LGKPNDKAKRDFTLRKGTGVAIPVWAF 393
+ + YLDMV++E LR++PP R QD LG+ + G + + V A
Sbjct: 389 EGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQ---------RIPAGAVLEMAVGAL 439
Query: 392 HRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQLLQ 213
H +PE +P P F+PERF+ E + +PF YLPFG GPR+C+G R L EVK+ +L
Sbjct: 440 HHDPEHWPSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLH 499
Query: 212 HMEISPCEKTCIPSKLSKET 153
C +T +P +L ++
Sbjct: 500 KFRFQACPETQVPLQLESKS 519
>AF233616-1|AAF99270.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 101 bits (242), Expect = 2e-21
Identities = 51/140 (36%), Positives = 76/140 (54%), Gaps = 1/140 (0%)
Frame = -3
Query: 569 QNMVYLDMVVSELLRLWPPGVSMDRICVQDYN-LGKPNDKAKRDFTLRKGTGVAIPVWAF 393
+ + YLDMV++E LR++PP R QD LG+ + G + + V A
Sbjct: 389 EGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQ---------RIPAGAVLEMAVGAL 439
Query: 392 HRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQLLQ 213
H +PE +P P F+PERF+ E + +PF YLPFG GPR+C+G R L EVK+ +L
Sbjct: 440 HHDPEHWPSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLH 499
Query: 212 HMEISPCEKTCIPSKLSKET 153
C +T +P +L ++
Sbjct: 500 KFRFQACPETQVPLQLESKS 519
>AF233615-1|AAF99269.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 101 bits (242), Expect = 2e-21
Identities = 51/140 (36%), Positives = 76/140 (54%), Gaps = 1/140 (0%)
Frame = -3
Query: 569 QNMVYLDMVVSELLRLWPPGVSMDRICVQDYN-LGKPNDKAKRDFTLRKGTGVAIPVWAF 393
+ + YLDMV++E LR++PP R QD LG+ + G + + V A
Sbjct: 389 EGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQ---------RIPAGAVLEMAVGAL 439
Query: 392 HRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQLLQ 213
H +PE +P P F+PERF+ E + +PF YLPFG GPR+C+G R L EVK+ +L
Sbjct: 440 HHDPEHWPSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLH 499
Query: 212 HMEISPCEKTCIPSKLSKET 153
C +T +P +L ++
Sbjct: 500 KFRFQACPETQVPLQLESKS 519
>AF233625-1|AAF99279.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 101 bits (241), Expect = 2e-21
Identities = 51/140 (36%), Positives = 76/140 (54%), Gaps = 1/140 (0%)
Frame = -3
Query: 569 QNMVYLDMVVSELLRLWPPGVSMDRICVQDYN-LGKPNDKAKRDFTLRKGTGVAIPVWAF 393
+ + YLDMV++E LR++PP R QD LG+ + G + + V A
Sbjct: 389 EGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQ---------RIPAGAVLEMAVGAL 439
Query: 392 HRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQLLQ 213
H +PE +P P F+PERF+ E + +PF YLPFG GPR+C+G R L EVK+ +L
Sbjct: 440 HHDPEHWPSPETFNPERFTAEARQQHQPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLH 499
Query: 212 HMEISPCEKTCIPSKLSKET 153
C +T +P +L ++
Sbjct: 500 KFRFQACPETQVPLQLESKS 519
>AF233622-1|AAF99276.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 100 bits (239), Expect = 4e-21
Identities = 50/140 (35%), Positives = 76/140 (54%), Gaps = 1/140 (0%)
Frame = -3
Query: 569 QNMVYLDMVVSELLRLWPPGVSMDRICVQDYN-LGKPNDKAKRDFTLRKGTGVAIPVWAF 393
+ + YLDMV++E LR++PP R +D LG+ + G + + V A
Sbjct: 389 EGLPYLDMVIAETLRMYPPAFRFTREAAEDCEVLGQ---------RIPAGAVLEMAVGAL 439
Query: 392 HRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQLLQ 213
H +PE +P P F+PERF+ E + +PF YLPFG GPR+C+G R L EVK+ +L
Sbjct: 440 HHDPEHWPSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLH 499
Query: 212 HMEISPCEKTCIPSKLSKET 153
C +T +P +L ++
Sbjct: 500 KFRFQACPETQVPLQLESKS 519
>BC060857-1|AAH60857.1| 525|Homo sapiens cytochrome P450, family 4,
subfamily V, polypeptide 2 protein.
Length = 525
Score = 99 bits (238), Expect = 6e-21
Identities = 57/158 (36%), Positives = 84/158 (53%), Gaps = 1/158 (0%)
Frame = -3
Query: 572 IQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPVWAF 393
++ + YL+ V+ E LRL+P R +D + + + KGT I +A
Sbjct: 375 LKKLRYLECVIKETLRLFPSVPLFARSVSEDCEVA--------GYRVLKGTEAVIIPYAL 426
Query: 392 HRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQLLQ 213
HR+P +FP+P +F PERF EN P+AY+PF GPRNCIG +FA+ E K + +L+
Sbjct: 427 HRDPRYFPNPEEFQPERFFPENAQGRHPYAYVPFSAGPRNCIGQKFAVMEEKTILSCILR 486
Query: 212 HMEISPCEKTCIPSKLSKE-TFNLRLEGGHWVRLKIRD 102
H I +K +L E LR G W++LK R+
Sbjct: 487 HFWIESNQKR---EELGLEGQLILRPSNGIWIKLKRRN 521
>AY422002-1|AAR31180.1| 525|Homo sapiens cytochrome P450 4V2
protein.
Length = 525
Score = 99 bits (238), Expect = 6e-21
Identities = 57/158 (36%), Positives = 84/158 (53%), Gaps = 1/158 (0%)
Frame = -3
Query: 572 IQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPVWAF 393
++ + YL+ V+ E LRL+P R +D + + + KGT I +A
Sbjct: 375 LKKLRYLECVIKETLRLFPSVPLFARSVSEDCEVA--------GYRVLKGTEAVIIPYAL 426
Query: 392 HRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQLLQ 213
HR+P +FP+P +F PERF EN P+AY+PF GPRNCIG +FA+ E K + +L+
Sbjct: 427 HRDPRYFPNPEEFQPERFFPENAQGRHPYAYVPFSAGPRNCIGQKFAVMEEKTILSCILR 486
Query: 212 HMEISPCEKTCIPSKLSKE-TFNLRLEGGHWVRLKIRD 102
H I +K +L E LR G W++LK R+
Sbjct: 487 HFWIESNQKR---EELGLEGQLILRPSNGIWIKLKRRN 521
>AK126473-1|BAC86562.1| 503|Homo sapiens protein ( Homo sapiens
cDNA FLJ44509 fis, clone UTERU3001585, weakly similar
to Cytochrome P450 4c3 (EC 1.14.-.-). ).
Length = 503
Score = 99 bits (238), Expect = 6e-21
Identities = 57/158 (36%), Positives = 84/158 (53%), Gaps = 1/158 (0%)
Frame = -3
Query: 572 IQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPVWAF 393
++ + YL+ V+ E LRL+P R +D + + + KGT I +A
Sbjct: 353 LKKLRYLECVIKETLRLFPSVPLFARSVSEDCEVA--------GYRVLKGTEAVIIPYAL 404
Query: 392 HRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQLLQ 213
HR+P +FP+P +F PERF EN P+AY+PF GPRNCIG +FA+ E K + +L+
Sbjct: 405 HRDPRYFPNPEEFQPERFFPENAQGRHPYAYVPFSAGPRNCIGQKFAVMEEKTILSCILR 464
Query: 212 HMEISPCEKTCIPSKLSKE-TFNLRLEGGHWVRLKIRD 102
H I +K +L E LR G W++LK R+
Sbjct: 465 HFWIESNQKR---EELGLEGQLILRPSNGIWIKLKRRN 499
>AK122600-1|BAC85487.1| 525|Homo sapiens protein ( Homo sapiens
cDNA FLJ16007 fis, clone KIDNE2006580, weakly similar
to CYTOCHROME P450 4C1 (EC 1.14.14.1). ).
Length = 525
Score = 99 bits (238), Expect = 6e-21
Identities = 57/158 (36%), Positives = 84/158 (53%), Gaps = 1/158 (0%)
Frame = -3
Query: 572 IQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPVWAF 393
++ + YL+ V+ E LRL+P R +D + + + KGT I +A
Sbjct: 375 LKKLRYLECVIKETLRLFPSVPLFARSVSEDCEVA--------GYRVLKGTEAVIIPYAL 426
Query: 392 HRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQLLQ 213
HR+P +FP+P +F PERF EN P+AY+PF GPRNCIG +FA+ E K + +L+
Sbjct: 427 HRDPRYFPNPEEFQPERFFPENAQGRHPYAYVPFSAGPRNCIGQKFAVMEEKTILSCILR 486
Query: 212 HMEISPCEKTCIPSKLSKE-TFNLRLEGGHWVRLKIRD 102
H I +K +L E LR G W++LK R+
Sbjct: 487 HFWIESNQKR---EELGLEGQLILRPSNGIWIKLKRRN 521
>D34625-1|BAA07011.1| 533|Homo sapiens thromboxane synthase
protein.
Length = 533
Score = 99.5 bits (237), Expect = 8e-21
Identities = 50/140 (35%), Positives = 75/140 (53%), Gaps = 1/140 (0%)
Frame = -3
Query: 569 QNMVYLDMVVSELLRLWPPGVSMDRICVQDYN-LGKPNDKAKRDFTLRKGTGVAIPVWAF 393
+ + YLDMV++E LR++PP R QD LG+ + G + + V A
Sbjct: 388 EGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQ---------RIPAGAVLEMAVGAL 438
Query: 392 HRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQLLQ 213
H +PE +P P F+PERF+ E + +PF YLPFG GPR+C+G L EVK+ +L
Sbjct: 439 HHDPEHWPSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVHLGLLEVKLTLLHVLH 498
Query: 212 HMEISPCEKTCIPSKLSKET 153
C +T +P +L ++
Sbjct: 499 KFRFQACPETQVPLQLESKS 518
>AF133298-1|AAD49566.1| 520|Homo sapiens cytochrome P450 protein.
Length = 520
Score = 98.7 bits (235), Expect = 1e-20
Identities = 56/158 (35%), Positives = 83/158 (52%)
Frame = -3
Query: 584 DYNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIP 405
+++ + + +L M + E LRL PP + R C QD L P+ + + KG I
Sbjct: 371 EWDDLAQLPFLTMCLKESLRLHPPIPTFARGCTQDVVL--PDSRV-----IPKGNVCNIN 423
Query: 404 VWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAY 225
++A H NP +PDP +DP RF EN P A++PF GPRNCIG +FA+ E+KV+
Sbjct: 424 IFAIHHNPSVWPDPEVYDPFRFDPENAQKRSPMAFIPFSAGPRNCIGQKFAMAEMKVVLA 483
Query: 224 QLLQHMEISPCEKTCIPSKLSKETFNLRLEGGHWVRLK 111
L I P + P + + LR E G W+R++
Sbjct: 484 LTLLRFRILPDHRE--PRRTPE--IVLRAEDGLWLRVE 517
>AY792513-1|AAV40834.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 3 protein.
Length = 520
Score = 97.9 bits (233), Expect = 2e-20
Identities = 56/158 (35%), Positives = 82/158 (51%)
Frame = -3
Query: 584 DYNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIP 405
+++ + + +L M + E LRL PP ++ R C QD L P+ + + KG I
Sbjct: 371 EWDDLAQLPFLTMCIKESLRLHPPVPAVSRCCTQDIVL--PDGRV-----IPKGIICLIS 423
Query: 404 VWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAY 225
V+ H NP +PDP +DP RF +N P A++PF GPRNCIG FA+ E+KV+
Sbjct: 424 VFGTHHNPAVWPDPEVYDPFRFDPKNIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLG 483
Query: 224 QLLQHMEISPCEKTCIPSKLSKETFNLRLEGGHWVRLK 111
L + P P + K LR EGG W+R++
Sbjct: 484 LTLLRFRVLPDHTE--PRR--KPELVLRAEGGLWLRVE 517
>AF054821-1|AAC08589.1| 520|Homo sapiens cytochrome P-450 protein.
Length = 520
Score = 97.9 bits (233), Expect = 2e-20
Identities = 56/158 (35%), Positives = 82/158 (51%)
Frame = -3
Query: 584 DYNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIP 405
+++ + + +L M + E LRL PP ++ R C QD L P+ + + KG I
Sbjct: 371 EWDDLAQLPFLTMCIKESLRLHPPVPAVSRCCTQDIVL--PDGRV-----IPKGIICLIS 423
Query: 404 VWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAY 225
V+ H NP +PDP +DP RF +N P A++PF GPRNCIG FA+ E+KV+
Sbjct: 424 VFGTHHNPAVWPDPEVYDPFRFDPKNIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLG 483
Query: 224 QLLQHMEISPCEKTCIPSKLSKETFNLRLEGGHWVRLK 111
L + P P + K LR EGG W+R++
Sbjct: 484 LTLLRFRVLPDHTE--PRR--KPELVLRAEGGIWLRVE 517
>D12620-1|BAA02144.1| 520|Homo sapiens cytochrome P-450LTBV
protein.
Length = 520
Score = 97.1 bits (231), Expect = 4e-20
Identities = 56/158 (35%), Positives = 82/158 (51%)
Frame = -3
Query: 584 DYNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIP 405
+++ + + +L M + E LRL PP ++ R C QD L P+ + + KG I
Sbjct: 371 EWDDLAQLPFLTMCIKESLRLHPPVPAVSRCCTQDIVL--PDGRV-----IPKGIICLIS 423
Query: 404 VWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAY 225
V+ H NP +PDP +DP RF +N P A++PF GPRNCIG FA+ E+KV+
Sbjct: 424 VFGTHHNPAVWPDPEVYDPFRFDPKNIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLG 483
Query: 224 QLLQHMEISPCEKTCIPSKLSKETFNLRLEGGHWVRLK 111
L + P P + K LR EGG W+R++
Sbjct: 484 LTLLAFRVLPDHTE--PRR--KPELVLRAEGGLWLRVE 517
>AB002461-1|BAA25991.1| 520|Homo sapiens leukotriene B4
omega-hydroxylase protein.
Length = 520
Score = 97.1 bits (231), Expect = 4e-20
Identities = 56/158 (35%), Positives = 82/158 (51%)
Frame = -3
Query: 584 DYNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIP 405
+++ + + +L M + E LRL PP ++ R C QD L P+ + + KG I
Sbjct: 371 EWDDLAQLPFLTMCIKESLRLHPPVPAVSRCCTQDIVL--PDGRV-----IPKGIICLIS 423
Query: 404 VWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAY 225
V+ H NP +PDP +DP RF +N P A++PF GPRNCIG FA+ E+KV+
Sbjct: 424 VFGTHHNPAVWPDPEVYDPFRFDPKNIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLG 483
Query: 224 QLLQHMEISPCEKTCIPSKLSKETFNLRLEGGHWVRLK 111
L + P P + K LR EGG W+R++
Sbjct: 484 LTLLAFRVLPDHTE--PRR--KPELVLRAEGGLWLRVE 517
>AB002454-1|BAA25990.1| 520|Homo sapiens leukotriene B4
omega-hydroxylase protein.
Length = 520
Score = 97.1 bits (231), Expect = 4e-20
Identities = 56/158 (35%), Positives = 82/158 (51%)
Frame = -3
Query: 584 DYNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIP 405
+++ + + +L M + E LRL PP ++ R C QD L P+ + + KG I
Sbjct: 371 EWDDLAQLPFLTMCIKESLRLHPPVPAVSRCCTQDIVL--PDGRV-----IPKGIICLIS 423
Query: 404 VWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAY 225
V+ H NP +PDP +DP RF +N P A++PF GPRNCIG FA+ E+KV+
Sbjct: 424 VFGTHHNPAVWPDPEVYDPFRFDPKNIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLG 483
Query: 224 QLLQHMEISPCEKTCIPSKLSKETFNLRLEGGHWVRLK 111
L + P P + K LR EGG W+R++
Sbjct: 484 LTLLAFRVLPDHTE--PRR--KPELVLRAEGGLWLRVE 517
>X16699-1|CAA34672.1| 511|Homo sapiens protein ( Human mRNA for
cytochrome P-450HP. ).
Length = 511
Score = 94.7 bits (225), Expect = 2e-19
Identities = 57/159 (35%), Positives = 84/159 (52%)
Frame = -3
Query: 587 FDYNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAI 408
F ++ + M YL M + E RL+PP + R L KP +L G+ +++
Sbjct: 355 FQWDDLGKMTYLTMCIKESFRLYPPVPQVYR------QLSKPVTFVDGR-SLPAGSLISM 407
Query: 407 PVWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMA 228
++A HRN +PDP FD RFS EN PFA++PF GPRNCIG +FA+ E+KV+
Sbjct: 408 HIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVT 467
Query: 227 YQLLQHMEISPCEKTCIPSKLSKETFNLRLEGGHWVRLK 111
L E S + + +P K+ + LR + G + LK
Sbjct: 468 AMCLLRFEFS-LDPSRLPIKMPQ--LVLRSKNGFHLHLK 503
>J02871-1|AAA35712.1| 511|Homo sapiens protein ( Human lung
cytochrome P450 (IV subfamily) BI protein, complete cds.
).
Length = 511
Score = 94.7 bits (225), Expect = 2e-19
Identities = 57/159 (35%), Positives = 84/159 (52%)
Frame = -3
Query: 587 FDYNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAI 408
F ++ + M YL M + E RL+PP + R L KP +L G+ +++
Sbjct: 355 FQWDDLGKMTYLTMCIKESFRLYPPVPQVYR------QLSKPVTFVDGR-SLPAGSLISM 407
Query: 407 PVWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMA 228
++A HRN +PDP FD RFS EN PFA++PF GPRNCIG +FA+ E+KV+
Sbjct: 408 HIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVT 467
Query: 227 YQLLQHMEISPCEKTCIPSKLSKETFNLRLEGGHWVRLK 111
L E S + + +P K+ + LR + G + LK
Sbjct: 468 AMCLLRFEFS-LDPSRLPIKMPQ--LVLRSKNGFHLHLK 503
>DQ518907-1|ABF47106.1| 511|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 511
Score = 94.7 bits (225), Expect = 2e-19
Identities = 57/159 (35%), Positives = 84/159 (52%)
Frame = -3
Query: 587 FDYNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAI 408
F ++ + M YL M + E RL+PP + R L KP +L G+ +++
Sbjct: 355 FQWDDLGKMTYLTMCIKESFRLYPPVPQVYR------QLSKPVTFVDGR-SLPAGSLISM 407
Query: 407 PVWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMA 228
++A HRN +PDP FD RFS EN PFA++PF GPRNCIG +FA+ E+KV+
Sbjct: 408 HIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVT 467
Query: 227 YQLLQHMEISPCEKTCIPSKLSKETFNLRLEGGHWVRLK 111
L E S + + +P K+ + LR + G + LK
Sbjct: 468 AMCLLRFEFS-LDPSRLPIKMPQ--LVLRSKNGFHLHLK 503
>BC017758-1|AAH17758.1| 512|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 512
Score = 94.7 bits (225), Expect = 2e-19
Identities = 57/159 (35%), Positives = 84/159 (52%)
Frame = -3
Query: 587 FDYNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAI 408
F ++ + M YL M + E RL+PP + R L KP +L G+ +++
Sbjct: 356 FQWDDLGKMTYLTMCIKESFRLYPPVPQVYR------QLSKPVTFVDGR-SLPAGSLISM 408
Query: 407 PVWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMA 228
++A HRN +PDP FD RFS EN PFA++PF GPRNCIG +FA+ E+KV+
Sbjct: 409 HIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVT 468
Query: 227 YQLLQHMEISPCEKTCIPSKLSKETFNLRLEGGHWVRLK 111
L E S + + +P K+ + LR + G + LK
Sbjct: 469 AMCLLRFEFS-LDPSRLPIKMPQ--LVLRSKNGFHLHLK 504
>AY358631-1|AAQ88994.1| 505|Homo sapiens EPSW3060 protein.
Length = 505
Score = 94.7 bits (225), Expect = 2e-19
Identities = 49/129 (37%), Positives = 70/129 (54%)
Frame = -3
Query: 581 YNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPV 402
+ + M Y M + E LRL+ P V++ R+ D + P+ ++ L G V I +
Sbjct: 356 WEHLSQMPYTTMCIKECLRLYAPVVNISRLL--DKPITFPDGRS-----LPAGITVFINI 408
Query: 401 WAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQ 222
WA H NP F+ DP F+P RFS EN I P+A++PF G RNCIG FA+ E KV
Sbjct: 409 WALHHNPYFWEDPQVFNPLRFSRENSEKIHPYAFIPFSAGLRNCIGQHFAIIECKVAVAL 468
Query: 221 LLQHMEISP 195
L +++P
Sbjct: 469 TLLRFKLAP 477
>AY262056-1|AAO89257.1| 505|Homo sapiens cytochrome P450 protein.
Length = 505
Score = 94.7 bits (225), Expect = 2e-19
Identities = 49/129 (37%), Positives = 70/129 (54%)
Frame = -3
Query: 581 YNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPV 402
+ + M Y M + E LRL+ P V++ R+ D + P+ ++ L G V I +
Sbjct: 356 WEHLSQMPYTTMCIKECLRLYAPVVNISRLL--DKPITFPDGRS-----LPAGITVFINI 408
Query: 401 WAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQ 222
WA H NP F+ DP F+P RFS EN I P+A++PF G RNCIG FA+ E KV
Sbjct: 409 WALHHNPYFWEDPQVFNPLRFSRENSEKIHPYAFIPFSAGLRNCIGQHFAIIECKVAVAL 468
Query: 221 LLQHMEISP 195
L +++P
Sbjct: 469 TLLRFKLAP 477
>AY151049-1|AAN72312.1| 497|Homo sapiens pulmonary cytochrome P450
4B1 variant protein.
Length = 497
Score = 94.7 bits (225), Expect = 2e-19
Identities = 57/159 (35%), Positives = 84/159 (52%)
Frame = -3
Query: 587 FDYNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAI 408
F ++ + M YL M + E RL+PP + R L KP +L G+ +++
Sbjct: 341 FQWDDLGKMTYLTMCIKESFRLYPPVPQVYR------QLSKPVTFVDGR-SLPAGSLISM 393
Query: 407 PVWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMA 228
++A HRN +PDP FD RFS EN PFA++PF GPRNCIG +FA+ E+KV+
Sbjct: 394 HIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVT 453
Query: 227 YQLLQHMEISPCEKTCIPSKLSKETFNLRLEGGHWVRLK 111
L E S + + +P K+ + LR + G + LK
Sbjct: 454 AMCLLRFEFS-LDPSRLPIKMPQ--LVLRSKNGFHLHLK 489
>AY151048-1|AAN72311.1| 512|Homo sapiens pulmonary cytochrome P450
4B1 protein.
Length = 512
Score = 94.7 bits (225), Expect = 2e-19
Identities = 57/159 (35%), Positives = 84/159 (52%)
Frame = -3
Query: 587 FDYNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAI 408
F ++ + M YL M + E RL+PP + R L KP +L G+ +++
Sbjct: 356 FQWDDLGKMTYLTMCIKESFRLYPPVPQVYR------QLSKPVTFVDGR-SLPAGSLISM 408
Query: 407 PVWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMA 228
++A HRN +PDP FD RFS EN PFA++PF GPRNCIG +FA+ E+KV+
Sbjct: 409 HIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVT 468
Query: 227 YQLLQHMEISPCEKTCIPSKLSKETFNLRLEGGHWVRLK 111
L E S + + +P K+ + LR + G + LK
Sbjct: 469 AMCLLRFEFS-LDPSRLPIKMPQ--LVLRSKNGFHLHLK 504
>AY064486-1|AAL57721.1| 511|Homo sapiens cytochrome P450 protein.
Length = 511
Score = 94.7 bits (225), Expect = 2e-19
Identities = 57/159 (35%), Positives = 84/159 (52%)
Frame = -3
Query: 587 FDYNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAI 408
F ++ + M YL M + E RL+PP + R L KP +L G+ +++
Sbjct: 355 FQWDDLGKMTYLTMCIKESFRLYPPVPQVYR------QLSKPVTFVDGR-SLPAGSLISM 407
Query: 407 PVWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMA 228
++A HRN +PDP FD RFS EN PFA++PF GPRNCIG +FA+ E+KV+
Sbjct: 408 HIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVT 467
Query: 227 YQLLQHMEISPCEKTCIPSKLSKETFNLRLEGGHWVRLK 111
L E S + + +P K+ + LR + G + LK
Sbjct: 468 AMCLLRFEFS-LDPSRLPIKMPQ--LVLRSKNGFHLHLK 503
>AY064485-1|AAL57720.1| 511|Homo sapiens cytochrome P450 protein.
Length = 511
Score = 94.7 bits (225), Expect = 2e-19
Identities = 57/159 (35%), Positives = 84/159 (52%)
Frame = -3
Query: 587 FDYNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAI 408
F ++ + M YL M + E RL+PP + R L KP +L G+ +++
Sbjct: 355 FQWDDLGKMTYLTMCIKESFRLYPPVPQVYR------QLSKPVTFVDGR-SLPAGSLISM 407
Query: 407 PVWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMA 228
++A HRN +PDP FD RFS EN PFA++PF GPRNCIG +FA+ E+KV+
Sbjct: 408 HIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVT 467
Query: 227 YQLLQHMEISPCEKTCIPSKLSKETFNLRLEGGHWVRLK 111
L E S + + +P K+ + LR + G + LK
Sbjct: 468 AMCLLRFEFS-LDPSRLPIKMPQ--LVLRSKNGFHLHLK 503
>AL593856-7|CAI16982.1| 512|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 512
Score = 94.7 bits (225), Expect = 2e-19
Identities = 57/159 (35%), Positives = 84/159 (52%)
Frame = -3
Query: 587 FDYNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAI 408
F ++ + M YL M + E RL+PP + R L KP +L G+ +++
Sbjct: 356 FQWDDLGKMTYLTMCIKESFRLYPPVPQVYR------QLSKPVTFVDGR-SLPAGSLISM 408
Query: 407 PVWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMA 228
++A HRN +PDP FD RFS EN PFA++PF GPRNCIG +FA+ E+KV+
Sbjct: 409 HIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVT 468
Query: 227 YQLLQHMEISPCEKTCIPSKLSKETFNLRLEGGHWVRLK 111
L E S + + +P K+ + LR + G + LK
Sbjct: 469 AMCLLRFEFS-LDPSRLPIKMPQ--LVLRSKNGFHLHLK 504
>AL593856-6|CAI16981.1| 511|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 511
Score = 94.7 bits (225), Expect = 2e-19
Identities = 57/159 (35%), Positives = 84/159 (52%)
Frame = -3
Query: 587 FDYNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAI 408
F ++ + M YL M + E RL+PP + R L KP +L G+ +++
Sbjct: 355 FQWDDLGKMTYLTMCIKESFRLYPPVPQVYR------QLSKPVTFVDGR-SLPAGSLISM 407
Query: 407 PVWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMA 228
++A HRN +PDP FD RFS EN PFA++PF GPRNCIG +FA+ E+KV+
Sbjct: 408 HIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVT 467
Query: 227 YQLLQHMEISPCEKTCIPSKLSKETFNLRLEGGHWVRLK 111
L E S + + +P K+ + LR + G + LK
Sbjct: 468 AMCLLRFEFS-LDPSRLPIKMPQ--LVLRSKNGFHLHLK 503
>AL593856-5|CAI16983.1| 497|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 497
Score = 94.7 bits (225), Expect = 2e-19
Identities = 57/159 (35%), Positives = 84/159 (52%)
Frame = -3
Query: 587 FDYNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAI 408
F ++ + M YL M + E RL+PP + R L KP +L G+ +++
Sbjct: 341 FQWDDLGKMTYLTMCIKESFRLYPPVPQVYR------QLSKPVTFVDGR-SLPAGSLISM 393
Query: 407 PVWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMA 228
++A HRN +PDP FD RFS EN PFA++PF GPRNCIG +FA+ E+KV+
Sbjct: 394 HIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVT 453
Query: 227 YQLLQHMEISPCEKTCIPSKLSKETFNLRLEGGHWVRLK 111
L E S + + +P K+ + LR + G + LK
Sbjct: 454 AMCLLRFEFS-LDPSRLPIKMPQ--LVLRSKNGFHLHLK 489
>AL450996-2|CAH71036.1| 505|Homo sapiens cytochrome P450, family 4,
subfamily Z, polypeptide 1 protein.
Length = 505
Score = 94.7 bits (225), Expect = 2e-19
Identities = 49/129 (37%), Positives = 70/129 (54%)
Frame = -3
Query: 581 YNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPV 402
+ + M Y M + E LRL+ P V++ R+ D + P+ ++ L G V I +
Sbjct: 356 WEHLSQMPYTTMCIKECLRLYAPVVNISRLL--DKPITFPDGRS-----LPAGITVFINI 408
Query: 401 WAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQ 222
WA H NP F+ DP F+P RFS EN I P+A++PF G RNCIG FA+ E KV
Sbjct: 409 WALHHNPYFWEDPQVFNPLRFSRENSEKIHPYAFIPFSAGLRNCIGQHFAIIECKVAVAL 468
Query: 221 LLQHMEISP 195
L +++P
Sbjct: 469 TLLRFKLAP 477
>AL356793-4|CAI22557.1| 512|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 512
Score = 94.7 bits (225), Expect = 2e-19
Identities = 57/159 (35%), Positives = 84/159 (52%)
Frame = -3
Query: 587 FDYNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAI 408
F ++ + M YL M + E RL+PP + R L KP +L G+ +++
Sbjct: 356 FQWDDLGKMTYLTMCIKESFRLYPPVPQVYR------QLSKPVTFVDGR-SLPAGSLISM 408
Query: 407 PVWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMA 228
++A HRN +PDP FD RFS EN PFA++PF GPRNCIG +FA+ E+KV+
Sbjct: 409 HIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVT 468
Query: 227 YQLLQHMEISPCEKTCIPSKLSKETFNLRLEGGHWVRLK 111
L E S + + +P K+ + LR + G + LK
Sbjct: 469 AMCLLRFEFS-LDPSRLPIKMPQ--LVLRSKNGFHLHLK 504
>AL356793-3|CAI22559.1| 511|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 511
Score = 94.7 bits (225), Expect = 2e-19
Identities = 57/159 (35%), Positives = 84/159 (52%)
Frame = -3
Query: 587 FDYNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAI 408
F ++ + M YL M + E RL+PP + R L KP +L G+ +++
Sbjct: 355 FQWDDLGKMTYLTMCIKESFRLYPPVPQVYR------QLSKPVTFVDGR-SLPAGSLISM 407
Query: 407 PVWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMA 228
++A HRN +PDP FD RFS EN PFA++PF GPRNCIG +FA+ E+KV+
Sbjct: 408 HIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVT 467
Query: 227 YQLLQHMEISPCEKTCIPSKLSKETFNLRLEGGHWVRLK 111
L E S + + +P K+ + LR + G + LK
Sbjct: 468 AMCLLRFEFS-LDPSRLPIKMPQ--LVLRSKNGFHLHLK 503
>AL356793-2|CAI22558.1| 497|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 497
Score = 94.7 bits (225), Expect = 2e-19
Identities = 57/159 (35%), Positives = 84/159 (52%)
Frame = -3
Query: 587 FDYNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAI 408
F ++ + M YL M + E RL+PP + R L KP +L G+ +++
Sbjct: 341 FQWDDLGKMTYLTMCIKESFRLYPPVPQVYR------QLSKPVTFVDGR-SLPAGSLISM 393
Query: 407 PVWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMA 228
++A HRN +PDP FD RFS EN PFA++PF GPRNCIG +FA+ E+KV+
Sbjct: 394 HIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVT 453
Query: 227 YQLLQHMEISPCEKTCIPSKLSKETFNLRLEGGHWVRLK 111
L E S + + +P K+ + LR + G + LK
Sbjct: 454 AMCLLRFEFS-LDPSRLPIKMPQ--LVLRSKNGFHLHLK 489
>AL135960-6|CAI19734.1| 505|Homo sapiens cytochrome P450, family 4,
subfamily Z, polypeptide 1 protein.
Length = 505
Score = 94.7 bits (225), Expect = 2e-19
Identities = 49/129 (37%), Positives = 70/129 (54%)
Frame = -3
Query: 581 YNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPV 402
+ + M Y M + E LRL+ P V++ R+ D + P+ ++ L G V I +
Sbjct: 356 WEHLSQMPYTTMCIKECLRLYAPVVNISRLL--DKPITFPDGRS-----LPAGITVFINI 408
Query: 401 WAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQ 222
WA H NP F+ DP F+P RFS EN I P+A++PF G RNCIG FA+ E KV
Sbjct: 409 WALHHNPYFWEDPQVFNPLRFSRENSEKIHPYAFIPFSAGLRNCIGQHFAIIECKVAVAL 468
Query: 221 LLQHMEISP 195
L +++P
Sbjct: 469 TLLRFKLAP 477
>AF491285-1|AAM09532.1| 511|Homo sapiens cytochrome P450 protein.
Length = 511
Score = 94.7 bits (225), Expect = 2e-19
Identities = 57/159 (35%), Positives = 84/159 (52%)
Frame = -3
Query: 587 FDYNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAI 408
F ++ + M YL M + E RL+PP + R L KP +L G+ +++
Sbjct: 355 FQWDDLGKMTYLTMCIKESFRLYPPVPQVYR------QLSKPVTFVDGR-SLPAGSLISM 407
Query: 407 PVWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMA 228
++A HRN +PDP FD RFS EN PFA++PF GPRNCIG +FA+ E+KV+
Sbjct: 408 HIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVT 467
Query: 227 YQLLQHMEISPCEKTCIPSKLSKETFNLRLEGGHWVRLK 111
L E S + + +P K+ + LR + G + LK
Sbjct: 468 AMCLLRFEFS-LDPSRLPIKMPQ--LVLRSKNGFHLHLK 503
>BC067440-1|AAH67440.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 2 protein.
Length = 520
Score = 93.9 bits (223), Expect = 4e-19
Identities = 56/158 (35%), Positives = 81/158 (51%)
Frame = -3
Query: 584 DYNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIP 405
+++ + ++ +L M + E LRL PP + R QD L P+ + + KG I
Sbjct: 371 EWDDLAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVL--PDGRV-----IPKGIICLIS 423
Query: 404 VWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAY 225
V+ H NP +PDP +DP RF EN P A++PF GPRNCIG FA+ E+KV+
Sbjct: 424 VFGTHHNPAMWPDPEVYDPFRFDPENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKVVLA 483
Query: 224 QLLQHMEISPCEKTCIPSKLSKETFNLRLEGGHWVRLK 111
L + P P + K LR EGG W+R++
Sbjct: 484 LTLLRFRVLPDHTE--PRR--KPELVLRAEGGLWLRVE 517
>AB015306-1|BAA75823.1| 520|Homo sapiens Leukotriene B4
omega-hydroxylase protein.
Length = 520
Score = 93.9 bits (223), Expect = 4e-19
Identities = 56/158 (35%), Positives = 81/158 (51%)
Frame = -3
Query: 584 DYNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIP 405
+++ + ++ +L M + E LRL PP + R QD L P+ + + KG I
Sbjct: 371 EWDDLAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVL--PDGRV-----IPKGIICLIS 423
Query: 404 VWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAY 225
V+ H NP +PDP +DP RF EN P A++PF GPRNCIG FA+ E+KV+
Sbjct: 424 VFGTHHNPAMWPDPEVYDPFRFDPENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKVVLA 483
Query: 224 QLLQHMEISPCEKTCIPSKLSKETFNLRLEGGHWVRLK 111
L + P P + K LR EGG W+R++
Sbjct: 484 LTLLRFRVLPDHTE--PRR--KPELVLRAEGGLWLRVE 517
>D26480-1|BAA05490.1| 520|Homo sapiens leukotriene B4
omega-hydroxylase protein.
Length = 520
Score = 93.5 bits (222), Expect = 5e-19
Identities = 56/158 (35%), Positives = 81/158 (51%)
Frame = -3
Query: 584 DYNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIP 405
+++ + ++ +L M + E LRL PP + R QD L P+ + + KG I
Sbjct: 371 EWDDLAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVL--PDGRV-----IPKGIICLIS 423
Query: 404 VWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAY 225
V+ H NP +PDP +DP RF EN P A++PF GPRNCIG FA+ E+KV+
Sbjct: 424 VFGTHHNPAVWPDPEVYDPFRFDPENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKVVLA 483
Query: 224 QLLQHMEISPCEKTCIPSKLSKETFNLRLEGGHWVRLK 111
L + P P + K LR EGG W+R++
Sbjct: 484 LTLLRFRVLPDHTE--PRR--KPELVLRAEGGLWLRVE 517
>BC067439-1|AAH67439.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 2 protein.
Length = 520
Score = 93.5 bits (222), Expect = 5e-19
Identities = 56/158 (35%), Positives = 81/158 (51%)
Frame = -3
Query: 584 DYNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIP 405
+++ + ++ +L M + E LRL PP + R QD L P+ + + KG I
Sbjct: 371 EWDDLAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVL--PDGRV-----IPKGIICLIS 423
Query: 404 VWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAY 225
V+ H NP +PDP +DP RF EN P A++PF GPRNCIG FA+ E+KV+
Sbjct: 424 VFGTHHNPAVWPDPEVYDPFRFDPENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKVVLA 483
Query: 224 QLLQHMEISPCEKTCIPSKLSKETFNLRLEGGHWVRLK 111
L + P P + K LR EGG W+R++
Sbjct: 484 LTLLRFRVLPDHTE--PRR--KPELVLRAEGGLWLRVE 517
>BC067437-1|AAH67437.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 2 protein.
Length = 520
Score = 93.5 bits (222), Expect = 5e-19
Identities = 56/158 (35%), Positives = 81/158 (51%)
Frame = -3
Query: 584 DYNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIP 405
+++ + ++ +L M + E LRL PP + R QD L P+ + + KG I
Sbjct: 371 EWDDLAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVL--PDGRV-----IPKGIICLIS 423
Query: 404 VWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAY 225
V+ H NP +PDP +DP RF EN P A++PF GPRNCIG FA+ E+KV+
Sbjct: 424 VFGTHHNPAVWPDPEVYDPFRFDPENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKVVLA 483
Query: 224 QLLQHMEISPCEKTCIPSKLSKETFNLRLEGGHWVRLK 111
L + P P + K LR EGG W+R++
Sbjct: 484 LTLLRFRVLPDHTE--PRR--KPELVLRAEGGLWLRVE 517
>AF467894-1|AAL67578.1| 520|Homo sapiens cytochrome P450, subfamily
IVF, polypeptide 2 protein.
Length = 520
Score = 93.5 bits (222), Expect = 5e-19
Identities = 56/158 (35%), Positives = 81/158 (51%)
Frame = -3
Query: 584 DYNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIP 405
+++ + ++ +L M + E LRL PP + R QD L P+ + + KG I
Sbjct: 371 EWDDLAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVL--PDGRV-----IPKGIICLIS 423
Query: 404 VWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAY 225
V+ H NP +PDP +DP RF EN P A++PF GPRNCIG FA+ E+KV+
Sbjct: 424 VFGTHHNPAVWPDPEVYDPFRFDPENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKVVLA 483
Query: 224 QLLQHMEISPCEKTCIPSKLSKETFNLRLEGGHWVRLK 111
L + P P + K LR EGG W+R++
Sbjct: 484 LTLLRFRVLPDHTE--PRR--KPELVLRAEGGLWLRVE 517
>AC005336-1|AAC27730.1| 520|Homo sapiens CYP4F2 protein.
Length = 520
Score = 93.5 bits (222), Expect = 5e-19
Identities = 56/158 (35%), Positives = 81/158 (51%)
Frame = -3
Query: 584 DYNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIP 405
+++ + ++ +L M + E LRL PP + R QD L P+ + + KG I
Sbjct: 371 EWDDLAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVL--PDGRV-----IPKGIICLIS 423
Query: 404 VWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAY 225
V+ H NP +PDP +DP RF EN P A++PF GPRNCIG FA+ E+KV+
Sbjct: 424 VFGTHHNPAVWPDPEVYDPFRFDPENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKVVLA 483
Query: 224 QLLQHMEISPCEKTCIPSKLSKETFNLRLEGGHWVRLK 111
L + P P + K LR EGG W+R++
Sbjct: 484 LTLLRFRVLPDHTE--PRR--KPELVLRAEGGLWLRVE 517
>U02388-1|AAC50052.2| 520|Homo sapiens cytochrome P450 4F2 protein.
Length = 520
Score = 92.3 bits (219), Expect = 1e-18
Identities = 55/158 (34%), Positives = 81/158 (51%)
Frame = -3
Query: 584 DYNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIP 405
+++ + ++ +L M + E LR+ PP + R QD L P+ + + KG I
Sbjct: 371 EWDDLAHLPFLTMCMKESLRVHPPVPVISRHVTQDIVL--PDGRV-----IPKGIICLIS 423
Query: 404 VWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAY 225
V+ H NP +PDP +DP RF EN P A++PF GPRNCIG FA+ E+KV+
Sbjct: 424 VFGTHHNPAVWPDPEVYDPFRFDPENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKVVLA 483
Query: 224 QLLQHMEISPCEKTCIPSKLSKETFNLRLEGGHWVRLK 111
L + P P + K LR EGG W+R++
Sbjct: 484 LTLLRFRVLPDHTE--PRR--KPELVLRAEGGLWLRVE 517
>BC028102-1|AAH28102.1| 509|Homo sapiens cytochrome P450, family 4,
subfamily X, polypeptide 1 protein.
Length = 509
Score = 91.5 bits (217), Expect = 2e-18
Identities = 49/129 (37%), Positives = 66/129 (51%)
Frame = -3
Query: 581 YNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPV 402
++ + M Y M + E RL P S+ R +L KP TL G V + +
Sbjct: 358 WDQLGEMSYTTMCIKETCRLIPAVPSISR------DLSKPLTFPD-GCTLPAGITVVLSI 410
Query: 401 WAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQ 222
W H NP + +P FDP RFS+EN P+AYLPF G RNCIG FA+ E+KV
Sbjct: 411 WGLHHNPAVWKNPKVFDPLRFSQENSDQRHPYAYLPFSAGSRNCIGQEFAMIELKVTIAL 470
Query: 221 LLQHMEISP 195
+L H ++P
Sbjct: 471 ILLHFRVTP 479
>AY358537-1|AAQ88901.1| 509|Homo sapiens EFSW1929 protein.
Length = 509
Score = 91.5 bits (217), Expect = 2e-18
Identities = 49/129 (37%), Positives = 66/129 (51%)
Frame = -3
Query: 581 YNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPV 402
++ + M Y M + E RL P S+ R +L KP TL G V + +
Sbjct: 358 WDQLGEMSYTTMCIKETCRLIPAVPSISR------DLSKPLTFPD-GCTLPAGITVVLSI 410
Query: 401 WAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQ 222
W H NP + +P FDP RFS+EN P+AYLPF G RNCIG FA+ E+KV
Sbjct: 411 WGLHHNPAVWKNPKVFDPLRFSQENSDQRHPYAYLPFSAGSRNCIGQEFAMIELKVTIAL 470
Query: 221 LLQHMEISP 195
+L H ++P
Sbjct: 471 ILLHFRVTP 479
>AM040940-1|CAJ13826.1| 509|Homo sapiens cytochrome P450 protein.
Length = 509
Score = 91.5 bits (217), Expect = 2e-18
Identities = 49/129 (37%), Positives = 66/129 (51%)
Frame = -3
Query: 581 YNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPV 402
++ + M Y M + E RL P S+ R +L KP TL G V + +
Sbjct: 358 WDQLGEMSYTTMCIKETCRLIPAVPSISR------DLSKPLTFPD-GCTLPAGITVVLSI 410
Query: 401 WAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQ 222
W H NP + +P FDP RFS+EN P+AYLPF G RNCIG FA+ E+KV
Sbjct: 411 WGLHHNPAVWKNPKVFDPLRFSQENSDQRHPYAYLPFSAGSRNCIGQEFAMIELKVTIAL 470
Query: 221 LLQHMEISP 195
+L H ++P
Sbjct: 471 ILLHFRVTP 479
>AL450996-1|CAH71035.1| 509|Homo sapiens cytochrome P450, family 4,
subfamily X, polypeptide 1 protein.
Length = 509
Score = 91.5 bits (217), Expect = 2e-18
Identities = 49/129 (37%), Positives = 66/129 (51%)
Frame = -3
Query: 581 YNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPV 402
++ + M Y M + E RL P S+ R +L KP TL G V + +
Sbjct: 358 WDQLGEMSYTTMCIKETCRLIPAVPSISR------DLSKPLTFPD-GCTLPAGITVVLSI 410
Query: 401 WAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQ 222
W H NP + +P FDP RFS+EN P+AYLPF G RNCIG FA+ E+KV
Sbjct: 411 WGLHHNPAVWKNPKVFDPLRFSQENSDQRHPYAYLPFSAGSRNCIGQEFAMIELKVTIAL 470
Query: 221 LLQHMEISP 195
+L H ++P
Sbjct: 471 ILLHFRVTP 479
>AK131355-1|BAD18508.1| 508|Homo sapiens protein ( Homo sapiens
cDNA FLJ16384 fis, clone TLIVE2007607, weakly similar
to CYTOCHROME P450 4A4 (EC 1.14.14.1). ).
Length = 508
Score = 91.5 bits (217), Expect = 2e-18
Identities = 49/129 (37%), Positives = 66/129 (51%)
Frame = -3
Query: 581 YNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPV 402
++ + M Y M + E RL P S+ R +L KP TL G V + +
Sbjct: 357 WDQLGEMSYTTMCIKETCRLIPAVPSISR------DLSKPLTFPD-GCTLPAGITVVLSI 409
Query: 401 WAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQ 222
W H NP + +P FDP RFS+EN P+AYLPF G RNCIG FA+ E+KV
Sbjct: 410 WGLHHNPAVWKNPKVFDPLRFSQENSDQRHPYAYLPFSAGSRNCIGQEFAMIELKVTIAL 469
Query: 221 LLQHMEISP 195
+L H ++P
Sbjct: 470 ILLHFRVTP 478
>AK098065-1|BAC05226.1| 509|Homo sapiens protein ( Homo sapiens
cDNA FLJ40746 fis, clone TRACH2000359, weakly similar to
CYTOCHROME P450 4A4 (EC 1.14.14.1). ).
Length = 509
Score = 91.5 bits (217), Expect = 2e-18
Identities = 49/129 (37%), Positives = 66/129 (51%)
Frame = -3
Query: 581 YNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPV 402
++ + M Y M + E RL P S+ R +L KP TL G V + +
Sbjct: 358 WDQLGEMSYTTMCIKETCRLIPAVPSISR------DLSKPLTFPD-GCTLPAGITVVLSI 410
Query: 401 WAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQ 222
W H NP + +P FDP RFS+EN P+AYLPF G RNCIG FA+ E+KV
Sbjct: 411 WGLHHNPAVWKNPKVFDPLRFSQENSDQRHPYAYLPFSAGSRNCIGQEFAMIELKVTIAL 470
Query: 221 LLQHMEISP 195
+L H ++P
Sbjct: 471 ILLHFRVTP 479
>AK091806-1|BAC03751.1| 444|Homo sapiens protein ( Homo sapiens
cDNA FLJ34487 fis, clone HLUNG2004273, weakly similar to
CYTOCHROME P450 4A4 (EC 1.14.14.1). ).
Length = 444
Score = 91.5 bits (217), Expect = 2e-18
Identities = 49/129 (37%), Positives = 66/129 (51%)
Frame = -3
Query: 581 YNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPV 402
++ + M Y M + E RL P S+ R +L KP TL G V + +
Sbjct: 293 WDQLGEMSYTTMCIKETCRLIPAVPSISR------DLSKPLTFPD-GCTLPAGITVVLSI 345
Query: 401 WAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQ 222
W H NP + +P FDP RFS+EN P+AYLPF G RNCIG FA+ E+KV
Sbjct: 346 WGLHHNPAVWKNPKVFDPLRFSQENSDQRHPYAYLPFSAGSRNCIGQEFAMIELKVTIAL 405
Query: 221 LLQHMEISP 195
+L H ++P
Sbjct: 406 ILLHFRVTP 414
>BC093896-1|AAH93896.1| 531|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 22 protein.
Length = 531
Score = 86.6 bits (205), Expect = 6e-17
Identities = 47/158 (29%), Positives = 79/158 (50%)
Frame = -3
Query: 584 DYNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIP 405
+++ + + + M + E LR +PP + R C +D L P+ + + KG +
Sbjct: 378 EWDDLTQLPFTTMCIKESLRQYPPVTLVSRQCTEDIKL--PDGRI-----IPKGIICLVS 430
Query: 404 VWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAY 225
++ H NP +PD ++P RF +N P AY+PF GPRNCIG FA+ E++V+
Sbjct: 431 IYGTHHNPTVWPDSKVYNPYRFDPDNPQQRSPLAYVPFSAGPRNCIGQSFAMAELRVVVA 490
Query: 224 QLLQHMEISPCEKTCIPSKLSKETFNLRLEGGHWVRLK 111
L +S ++T K LR E G W++++
Sbjct: 491 LTLLRFRLS-VDRT--RKVRRKPELILRTENGLWLKVE 525
>BC093894-1|AAH93894.1| 531|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 22 protein.
Length = 531
Score = 86.6 bits (205), Expect = 6e-17
Identities = 47/158 (29%), Positives = 79/158 (50%)
Frame = -3
Query: 584 DYNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIP 405
+++ + + + M + E LR +PP + R C +D L P+ + + KG +
Sbjct: 378 EWDDLTQLPFTTMCIKESLRQYPPVTLVSRQCTEDIKL--PDGRI-----IPKGIICLVS 430
Query: 404 VWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAY 225
++ H NP +PD ++P RF +N P AY+PF GPRNCIG FA+ E++V+
Sbjct: 431 IYGTHHNPTVWPDSKVYNPYRFDPDNPQQRSPLAYVPFSAGPRNCIGQSFAMAELRVVVA 490
Query: 224 QLLQHMEISPCEKTCIPSKLSKETFNLRLEGGHWVRLK 111
L +S ++T K LR E G W++++
Sbjct: 491 LTLLRFRLS-VDRT--RKVRRKPELILRTENGLWLKVE 525
>BC069351-1|AAH69351.1| 531|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 22 protein.
Length = 531
Score = 86.6 bits (205), Expect = 6e-17
Identities = 47/158 (29%), Positives = 79/158 (50%)
Frame = -3
Query: 584 DYNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIP 405
+++ + + + M + E LR +PP + R C +D L P+ + + KG +
Sbjct: 378 EWDDLTQLPFTTMCIKESLRQYPPVTLVSRQCTEDIKL--PDGRI-----IPKGIICLVS 430
Query: 404 VWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAY 225
++ H NP +PD ++P RF +N P AY+PF GPRNCIG FA+ E++V+
Sbjct: 431 IYGTHHNPTVWPDSKVYNPYRFDPDNPQQRSPLAYVPFSAGPRNCIGQSFAMAELRVVVA 490
Query: 224 QLLQHMEISPCEKTCIPSKLSKETFNLRLEGGHWVRLK 111
L +S ++T K LR E G W++++
Sbjct: 491 LTLLRFRLS-VDRT--RKVRRKPELILRTENGLWLKVE 525
>AK096820-1|BAC04868.1| 531|Homo sapiens protein ( Homo sapiens
cDNA FLJ39501 fis, clone PROST2016980, moderately
similar to CYTOCHROME P450 4F2 (EC 1.14.13.30). ).
Length = 531
Score = 86.6 bits (205), Expect = 6e-17
Identities = 47/158 (29%), Positives = 79/158 (50%)
Frame = -3
Query: 584 DYNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIP 405
+++ + + + M + E LR +PP + R C +D L P+ + + KG +
Sbjct: 378 EWDDLTQLPFTTMCIKESLRQYPPVTLVSRQCTEDIKL--PDGRI-----IPKGIICLVS 430
Query: 404 VWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAY 225
++ H NP +PD ++P RF +N P AY+PF GPRNCIG FA+ E++V+
Sbjct: 431 IYGTHHNPTVWPDSKVYNPYRFDPDNPQQRSPLAYVPFSAGPRNCIGQSFAMAELRVVVA 490
Query: 224 QLLQHMEISPCEKTCIPSKLSKETFNLRLEGGHWVRLK 111
L +S ++T K LR E G W++++
Sbjct: 491 LTLLRFRLS-VDRT--RKVRRKPELILRTENGLWLKVE 525
>S67580-1|AAB29502.1| 519|Homo sapiens fatty acid omega-hydroxylase
protein.
Length = 519
Score = 80.2 bits (189), Expect = 5e-15
Identities = 54/166 (32%), Positives = 85/166 (51%)
Frame = -3
Query: 581 YNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPV 402
+N + M Y M + E LRL+PP + R P+ ++ L KG V + +
Sbjct: 363 WNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTF--PDGRS-----LPKGIMVLLSI 415
Query: 401 WAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQ 222
+ H NP+ +P+P FDP RF+ + + A+LPF G RNCIG +FA+ E+KV
Sbjct: 416 YGLHHNPKVWPNPEVFDPSRFAPGSAQH--SHAFLPFSGGSRNCIGKQFAMNELKVATAL 473
Query: 221 LLQHMEISPCEKTCIPSKLSKETFNLRLEGGHWVRLKIRD*LKNHC 84
L E+ P + T IP +++ L L+ + + L++R L N C
Sbjct: 474 TLLRFELLP-DPTRIPIPIAR----LVLKSKNGIHLRLRR-LPNPC 513
>S67581-1|AAB29503.1| 591|Homo sapiens fatty acid omega-hydroxylase
protein.
Length = 591
Score = 79.8 bits (188), Expect = 7e-15
Identities = 48/149 (32%), Positives = 76/149 (51%)
Frame = -3
Query: 581 YNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPV 402
+N + M Y M + E LRL+PP + R P+ ++ L KG V + +
Sbjct: 363 WNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTF--PDGRS-----LPKGIMVLLSI 415
Query: 401 WAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQ 222
+ H NP+ +P+P FDP RF+ + + A+LPF G RNCIG +FA+ E+KV
Sbjct: 416 YGLHHNPKVWPNPEVFDPSRFAPGSAQH--SHAFLPFSGGSRNCIGKQFAMNELKVATAL 473
Query: 221 LLQHMEISPCEKTCIPSKLSKETFNLRLE 135
L E+ P + T IP +++ ++E
Sbjct: 474 TLLRFELLP-DPTRIPIPIARLVLKSKME 501
>L04751-1|AAA58436.1| 519|Homo sapiens cytochrome P450 protein.
Length = 519
Score = 79.0 bits (186), Expect = 1e-14
Identities = 54/166 (32%), Positives = 85/166 (51%)
Frame = -3
Query: 581 YNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPV 402
+N + M Y M + E LRL+PP + R P+ ++ L KG V + +
Sbjct: 363 WNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTF--PDGRS-----LPKGIMVLLSI 415
Query: 401 WAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQ 222
+ H NP+ +P+P FDP RF+ + + A+LPF G RNCIG +FA+ E+KV
Sbjct: 416 YGLHHNPKVWPNPEVFDPFRFAPGSAQH--SHAFLPFSGGSRNCIGKQFAMNELKVATAL 473
Query: 221 LLQHMEISPCEKTCIPSKLSKETFNLRLEGGHWVRLKIRD*LKNHC 84
L E+ P + T IP +++ L L+ + + L++R L N C
Sbjct: 474 TLLRFELLP-DPTRIPIPIAR----LVLKSKNGIHLRLRR-LPNPC 513
>D26481-1|BAA05491.1| 519|Homo sapiens fatty acids
omega-hydroxylase protein.
Length = 519
Score = 79.0 bits (186), Expect = 1e-14
Identities = 54/166 (32%), Positives = 85/166 (51%)
Frame = -3
Query: 581 YNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPV 402
+N + M Y M + E LRL+PP + R P+ ++ L KG V + +
Sbjct: 363 WNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTF--PDGRS-----LPKGIMVLLSI 415
Query: 401 WAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQ 222
+ H NP+ +P+P FDP RF+ + + A+LPF G RNCIG +FA+ E+KV
Sbjct: 416 YGLHHNPKVWPNPEVFDPFRFAPGSAQH--SHAFLPFSGGSRNCIGKQFAMNELKVATAL 473
Query: 221 LLQHMEISPCEKTCIPSKLSKETFNLRLEGGHWVRLKIRD*LKNHC 84
L E+ P + T IP +++ L L+ + + L++R L N C
Sbjct: 474 TLLRFELLP-DPTRIPIPIAR----LVLKSKNGIHLRLRR-LPNPC 513
>AY369778-1|AAQ56847.1| 519|Homo sapiens cytochrome P450, family 4,
subfamily A, polypeptide 11 protein.
Length = 519
Score = 79.0 bits (186), Expect = 1e-14
Identities = 54/166 (32%), Positives = 85/166 (51%)
Frame = -3
Query: 581 YNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPV 402
+N + M Y M + E LRL+PP + R P+ ++ L KG V + +
Sbjct: 363 WNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTF--PDGRS-----LPKGIMVLLSI 415
Query: 401 WAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQ 222
+ H NP+ +P+P FDP RF+ + + A+LPF G RNCIG +FA+ E+KV
Sbjct: 416 YGLHHNPKVWPNPEVFDPFRFAPGSAQH--SHAFLPFSGGSRNCIGKQFAMNELKVATAL 473
Query: 221 LLQHMEISPCEKTCIPSKLSKETFNLRLEGGHWVRLKIRD*LKNHC 84
L E+ P + T IP +++ L L+ + + L++R L N C
Sbjct: 474 TLLRFELLP-DPTRIPIPIAR----LVLKSKNGIHLRLRR-LPNPC 513
>AL731892-3|CAH72778.1| 519|Homo sapiens cytochrome P450, family 4,
subfamily A, polypeptide 11 protein.
Length = 519
Score = 79.0 bits (186), Expect = 1e-14
Identities = 54/166 (32%), Positives = 85/166 (51%)
Frame = -3
Query: 581 YNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPV 402
+N + M Y M + E LRL+PP + R P+ ++ L KG V + +
Sbjct: 363 WNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTF--PDGRS-----LPKGIMVLLSI 415
Query: 401 WAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQ 222
+ H NP+ +P+P FDP RF+ + + A+LPF G RNCIG +FA+ E+KV
Sbjct: 416 YGLHHNPKVWPNPEVFDPFRFAPGSAQH--SHAFLPFSGGSRNCIGKQFAMNELKVATAL 473
Query: 221 LLQHMEISPCEKTCIPSKLSKETFNLRLEGGHWVRLKIRD*LKNHC 84
L E+ P + T IP +++ L L+ + + L++R L N C
Sbjct: 474 TLLRFELLP-DPTRIPIPIAR----LVLKSKNGIHLRLRR-LPNPC 513
>AF525488-1|AAO16078.1| 519|Homo sapiens cytochrome P450, subfamily
IVA, polypeptide 11 protein.
Length = 519
Score = 78.6 bits (185), Expect = 2e-14
Identities = 54/166 (32%), Positives = 85/166 (51%)
Frame = -3
Query: 581 YNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPV 402
+N + M Y M + E LRL+PP + R P+ ++ L KG V + +
Sbjct: 363 WNHLDQMPYTTMCIKEALRLFPPVPGIGRELSTPVTF--PDGRS-----LPKGIMVLLSI 415
Query: 401 WAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQ 222
+ H NP+ +P+P FDP RF+ + + A+LPF G RNCIG +FA+ E+KV
Sbjct: 416 YGLHHNPKVWPNPEVFDPFRFAPGSAQH--SHAFLPFSGGSRNCIGKQFAMNELKVATAL 473
Query: 221 LLQHMEISPCEKTCIPSKLSKETFNLRLEGGHWVRLKIRD*LKNHC 84
L E+ P + T IP +++ L L+ + + L++R L N C
Sbjct: 474 TLLRFELLP-DPTRIPIPIAR----LVLKSKNGIHLRLRR-LPNPC 513
>AY280372-1|AAQ21368.1| 519|Homo sapiens cytochrome P450 4A22
protein.
Length = 519
Score = 77.4 bits (182), Expect = 4e-14
Identities = 50/157 (31%), Positives = 81/157 (51%)
Frame = -3
Query: 581 YNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPV 402
+N + M Y M + E LRL+PP + R P+ ++ L KG V + +
Sbjct: 363 WNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTF--PDGRS-----LPKGIMVLLSI 415
Query: 401 WAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQ 222
+ H NP+ +P+P FDP RF+ + + A+LPF G RNCIG +FA+ ++KV
Sbjct: 416 YGLHHNPKVWPNPEVFDPSRFAPGSAQH--SHAFLPFSGGSRNCIGKQFAMNQLKVARAL 473
Query: 221 LLQHMEISPCEKTCIPSKLSKETFNLRLEGGHWVRLK 111
L E+ P + T IP +++ L+ + G +RL+
Sbjct: 474 TLLRFELLP-DPTRIPIPMAR--LVLKSKNGIHLRLR 507
>D13705-1|BAA02864.1| 521|Homo sapiens fatty acid omega-hydroxylase
protein.
Length = 521
Score = 76.2 bits (179), Expect = 8e-14
Identities = 55/167 (32%), Positives = 86/167 (51%), Gaps = 1/167 (0%)
Frame = -3
Query: 581 YNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPV 402
+N + M Y M + E LRL+PP + R P+ ++ L KG V + +
Sbjct: 364 WNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTF--PDGRS-----LPKGIMVLLSI 416
Query: 401 WAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQ 222
+ H NP+ +P+P FDP RF+ + + A+LPF G RNCIG +FA+ E+KV
Sbjct: 417 YGLHHNPKVWPNPEVFDPFRFAPGSAQH--SHAFLPFSGGSRNCIGKQFAMNELKVGQQA 474
Query: 221 L-LQHMEISPCEKTCIPSKLSKETFNLRLEGGHWVRLKIRD*LKNHC 84
L L E+ P + T IP +++ L L+ + + L++R L N C
Sbjct: 475 LTLVRFELLP-DPTRIPIPIAR----LVLKSKNGIHLRLRR-LPNPC 515
>AY280371-1|AAQ21367.1| 519|Homo sapiens cytochrome P450 4A22K
protein.
Length = 519
Score = 75.4 bits (177), Expect = 1e-13
Identities = 52/166 (31%), Positives = 84/166 (50%)
Frame = -3
Query: 581 YNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPV 402
+N + M Y M + E LRL+PP + R P+ ++ L KG V + +
Sbjct: 363 WNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTF--PDGRS-----LPKGIMVLLSI 415
Query: 401 WAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQ 222
+ H NP+ +P+P FDP RF+ + + A+LPF G RNCIG +FA+ ++KV
Sbjct: 416 YGLHHNPKVWPNPEVFDPFRFAPGSAQH--SHAFLPFSGGSRNCIGKQFAMNQLKVARAL 473
Query: 221 LLQHMEISPCEKTCIPSKLSKETFNLRLEGGHWVRLKIRD*LKNHC 84
L E+ P + T P +++ L L+ + + L++R L N C
Sbjct: 474 TLLRFELLP-DPTRTPIPMAR----LVLKSKNGIHLRLRR-LPNPC 513
>AL135960-9|CAI19737.1| 519|Homo sapiens cytochrome P450, family 4,
subfamily A, polypeptide 22 protein.
Length = 519
Score = 74.5 bits (175), Expect = 2e-13
Identities = 52/166 (31%), Positives = 84/166 (50%)
Frame = -3
Query: 581 YNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPV 402
+N + M Y M + E LRL+PP + R P+ ++ L KG V + +
Sbjct: 363 WNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTF--PDGRS-----LPKGIMVLLSI 415
Query: 401 WAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQ 222
+ H NP+ +P+ FDP RF+ + + A+LPF G RNCIG +FA+ ++KV
Sbjct: 416 YGLHHNPKVWPNLEVFDPSRFAPGSAQH--SHAFLPFSGGSRNCIGKQFAMNQLKVARAL 473
Query: 221 LLQHMEISPCEKTCIPSKLSKETFNLRLEGGHWVRLKIRD*LKNHC 84
L E+ P + T IP +++ L L+ + + L++R L N C
Sbjct: 474 TLLRFELLP-DPTRIPIPMAR----LVLKSKNGIHLRLRR-LPNPC 513
>AF208532-1|AAF76722.1| 519|Homo sapiens fatty acid
omega-hydroxylase CYP4A11 protein.
Length = 519
Score = 74.5 bits (175), Expect = 2e-13
Identities = 52/166 (31%), Positives = 84/166 (50%)
Frame = -3
Query: 581 YNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPV 402
+N + M Y M + E LRL+PP + R P+ ++ L KG V + +
Sbjct: 363 WNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTF--PDGRS-----LPKGIMVLLSI 415
Query: 401 WAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQ 222
+ H NP+ +P+ FDP RF+ + + A+LPF G RNCIG +FA+ ++KV
Sbjct: 416 YGLHHNPKVWPNLEVFDPSRFAPGSAQH--SHAFLPFSGGSRNCIGKQFAMNQLKVARAL 473
Query: 221 LLQHMEISPCEKTCIPSKLSKETFNLRLEGGHWVRLKIRD*LKNHC 84
L E+ P + T IP +++ L L+ + + L++R L N C
Sbjct: 474 TLLRFELLP-DPTRIPIPIAR----LVLKSKNGIHLRLRR-LPNPC 513
>AL135960-10|CAI19736.1| 421|Homo sapiens cytochrome P450, family
4, subfamily A, polypeptide 22 protein.
Length = 421
Score = 73.7 bits (173), Expect = 4e-13
Identities = 52/165 (31%), Positives = 83/165 (50%)
Frame = -3
Query: 578 NSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPVW 399
N + M Y M + E LRL+PP + R P+ ++ L KG V + ++
Sbjct: 266 NHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTF--PDGRS-----LPKGIMVLLSIY 318
Query: 398 AFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQL 219
H NP+ +P+ FDP RF+ + + A+LPF G RNCIG +FA+ ++KV
Sbjct: 319 GLHHNPKVWPNLEVFDPSRFAPGSAQH--SHAFLPFSGGSRNCIGKQFAMNQLKVARALT 376
Query: 218 LQHMEISPCEKTCIPSKLSKETFNLRLEGGHWVRLKIRD*LKNHC 84
L E+ P + T IP +++ L L+ + + L++R L N C
Sbjct: 377 LLRFELLP-DPTRIPIPMAR----LVLKSKNGIHLRLRR-LPNPC 415
>AY288916-1|AAP31972.1| 508|Homo sapiens cytochrome P450, family
27, subfamily B, polypeptide 1 protein.
Length = 508
Score = 73.3 bits (172), Expect = 6e-13
Identities = 44/126 (34%), Positives = 66/126 (52%)
Frame = -3
Query: 572 IQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPVWAF 393
+ + L VV E+LRL+P R+ +D ++G D+ + K T V + +A
Sbjct: 364 LSQLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVG--------DYIIPKNTLVTLCHYAT 415
Query: 392 HRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQLLQ 213
R+P FP+P F P R+ E PFA LPFG G R+C+G R A E+++ Q+L
Sbjct: 416 SRDPAQFPEPNSFRPARWLGEGP-TPHPFASLPFGFGKRSCMGRRLAELELQMALAQILT 474
Query: 212 HMEISP 195
H E+ P
Sbjct: 475 HFEVQP 480
>AF256213-1|AAG00416.1| 508|Homo sapiens 25- hydroxyvitamin
D-1-alpha-hydroxylase protein.
Length = 508
Score = 73.3 bits (172), Expect = 6e-13
Identities = 44/126 (34%), Positives = 66/126 (52%)
Frame = -3
Query: 572 IQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPVWAF 393
+ + L VV E+LRL+P R+ +D ++G D+ + K T V + +A
Sbjct: 364 LSQLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVG--------DYIIPKNTLVTLCHYAT 415
Query: 392 HRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQLLQ 213
R+P FP+P F P R+ E PFA LPFG G R+C+G R A E+++ Q+L
Sbjct: 416 SRDPAQFPEPNSFRPARWLGEGP-TPHPFASLPFGFGKRSCMGRRLAELELQMALAQILT 474
Query: 212 HMEISP 195
H E+ P
Sbjct: 475 HFEVQP 480
>AF246895-1|AAF64299.1| 508|Homo sapiens 25-hydroxyvitamin
D-1-alpha-hydroxylase protein.
Length = 508
Score = 73.3 bits (172), Expect = 6e-13
Identities = 44/126 (34%), Positives = 66/126 (52%)
Frame = -3
Query: 572 IQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPVWAF 393
+ + L VV E+LRL+P R+ +D ++G D+ + K T V + +A
Sbjct: 364 LSQLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVG--------DYIIPKNTLVTLCHYAT 415
Query: 392 HRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQLLQ 213
R+P FP+P F P R+ E PFA LPFG G R+C+G R A E+++ Q+L
Sbjct: 416 SRDPAQFPEPNSFRPARWLGEGP-TPHPFASLPFGFGKRSCMGRRLAELELQMALAQILT 474
Query: 212 HMEISP 195
H E+ P
Sbjct: 475 HFEVQP 480
>AF027152-1|AAC51854.1| 508|Homo sapiens P450 25-hydroxyvitamin D-1
alpha hydroxylase protein.
Length = 508
Score = 73.3 bits (172), Expect = 6e-13
Identities = 44/126 (34%), Positives = 66/126 (52%)
Frame = -3
Query: 572 IQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPVWAF 393
+ + L VV E+LRL+P R+ +D ++G D+ + K T V + +A
Sbjct: 364 LSQLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVG--------DYIIPKNTLVTLCHYAT 415
Query: 392 HRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQLLQ 213
R+P FP+P F P R+ E PFA LPFG G R+C+G R A E+++ Q+L
Sbjct: 416 SRDPAQFPEPNSFRPARWLGEGP-TPHPFASLPFGFGKRSCMGRRLAELELQMALAQILT 474
Query: 212 HMEISP 195
H E+ P
Sbjct: 475 HFEVQP 480
>AF020192-1|AAC51853.1| 508|Homo sapiens 25-hydroxyvitamin
D-1-alpha-hydroxylase protein.
Length = 508
Score = 73.3 bits (172), Expect = 6e-13
Identities = 44/126 (34%), Positives = 66/126 (52%)
Frame = -3
Query: 572 IQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPVWAF 393
+ + L VV E+LRL+P R+ +D ++G D+ + K T V + +A
Sbjct: 364 LSQLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVG--------DYIIPKNTLVTLCHYAT 415
Query: 392 HRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQLLQ 213
R+P FP+P F P R+ E PFA LPFG G R+C+G R A E+++ Q+L
Sbjct: 416 SRDPAQFPEPNSFRPARWLGEGP-TPHPFASLPFGFGKRSCMGRRLAELELQMALAQILT 474
Query: 212 HMEISP 195
H E+ P
Sbjct: 475 HFEVQP 480
>AB006987-1|BAA23418.1| 508|Homo sapiens 25-hydroxyvitamin D3
1-alpha-hydroxylase protein.
Length = 508
Score = 73.3 bits (172), Expect = 6e-13
Identities = 44/126 (34%), Positives = 66/126 (52%)
Frame = -3
Query: 572 IQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPVWAF 393
+ + L VV E+LRL+P R+ +D ++G D+ + K T V + +A
Sbjct: 364 LSQLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVG--------DYIIPKNTLVTLCHYAT 415
Query: 392 HRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQLLQ 213
R+P FP+P F P R+ E PFA LPFG G R+C+G R A E+++ Q+L
Sbjct: 416 SRDPAQFPEPNSFRPARWLGEGP-TPHPFASLPFGFGKRSCMGRRLAELELQMALAQILT 474
Query: 212 HMEISP 195
H E+ P
Sbjct: 475 HFEVQP 480
>AB005990-1|BAA22657.1| 508|Homo sapiens 25-hydroxyvitamin D3
1alpha-hydroxylase protein.
Length = 508
Score = 73.3 bits (172), Expect = 6e-13
Identities = 44/126 (34%), Positives = 66/126 (52%)
Frame = -3
Query: 572 IQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPVWAF 393
+ + L VV E+LRL+P R+ +D ++G D+ + K T V + +A
Sbjct: 364 LSQLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVG--------DYIIPKNTLVTLCHYAT 415
Query: 392 HRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQLLQ 213
R+P FP+P F P R+ E PFA LPFG G R+C+G R A E+++ Q+L
Sbjct: 416 SRDPAQFPEPNSFRPARWLGEGP-TPHPFASLPFGFGKRSCMGRRLAELELQMALAQILT 474
Query: 212 HMEISP 195
H E+ P
Sbjct: 475 HFEVQP 480
>AB005989-1|BAA22656.1| 508|Homo sapiens 25-hydroxyvitamin D3
1alpha-hydroxylase protein.
Length = 508
Score = 73.3 bits (172), Expect = 6e-13
Identities = 44/126 (34%), Positives = 66/126 (52%)
Frame = -3
Query: 572 IQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPVWAF 393
+ + L VV E+LRL+P R+ +D ++G D+ + K T V + +A
Sbjct: 364 LSQLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVG--------DYIIPKNTLVTLCHYAT 415
Query: 392 HRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQLLQ 213
R+P FP+P F P R+ E PFA LPFG G R+C+G R A E+++ Q+L
Sbjct: 416 SRDPAQFPEPNSFRPARWLGEGP-TPHPFASLPFGFGKRSCMGRRLAELELQMALAQILT 474
Query: 212 HMEISP 195
H E+ P
Sbjct: 475 HFEVQP 480
>AB005038-1|BAA23416.1| 508|Homo sapiens 25-hydroxyvitamin D3
1-alpha-hydroxylase protein.
Length = 508
Score = 73.3 bits (172), Expect = 6e-13
Identities = 44/126 (34%), Positives = 66/126 (52%)
Frame = -3
Query: 572 IQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPVWAF 393
+ + L VV E+LRL+P R+ +D ++G D+ + K T V + +A
Sbjct: 364 LSQLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVG--------DYIIPKNTLVTLCHYAT 415
Query: 392 HRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQLLQ 213
R+P FP+P F P R+ E PFA LPFG G R+C+G R A E+++ Q+L
Sbjct: 416 SRDPAQFPEPNSFRPARWLGEGP-TPHPFASLPFGFGKRSCMGRRLAELELQMALAQILT 474
Query: 212 HMEISP 195
H E+ P
Sbjct: 475 HFEVQP 480
>X05367-1|CAA28965.1| 521|Homo sapiens desmolase protein.
Length = 521
Score = 68.1 bits (159), Expect = 2e-11
Identities = 42/124 (33%), Positives = 62/124 (50%)
Frame = -3
Query: 572 IQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPVWAF 393
+Q + L + E LRL P V++ R V ND RD+ + T V + ++A
Sbjct: 371 LQLVPLLKASIKETLRLHPISVTLQRYLV--------NDLVLRDYMIPAKTLVQVAIYAL 422
Query: 392 HRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQLLQ 213
R P FF DP FDP R+ ++K NI F L FG G R C+G R A E+ + +L+
Sbjct: 423 GREPTFFFDPENFDPTRWLSKDK-NITYFRNLGFGWGVRQCLGRRIAELEMTIFLINMLE 481
Query: 212 HMEI 201
+ +
Sbjct: 482 NFRV 485
>M28253-1|AAA36404.1| 239|Homo sapiens cytochrome P-450-scc
protein.
Length = 239
Score = 68.1 bits (159), Expect = 2e-11
Identities = 42/124 (33%), Positives = 62/124 (50%)
Frame = -3
Query: 572 IQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPVWAF 393
+Q + L + E LRL P V++ R V ND RD+ + T V + ++A
Sbjct: 89 LQLVPLLKASIKETLRLHPISVTLQRYLV--------NDLVLRDYMIPAKTLVQVAIYAL 140
Query: 392 HRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQLLQ 213
R P FF DP FDP R+ ++K NI F L FG G R C+G R A E+ + +L+
Sbjct: 141 GREPTFFFDPENFDPTRWLSKDK-NITYFRNLGFGWGVRQCLGRRIAELEMTIFLINMLE 199
Query: 212 HMEI 201
+ +
Sbjct: 200 NFRV 203
>M14565-1|AAA52162.1| 521|Homo sapiens CYP11A protein.
Length = 521
Score = 68.1 bits (159), Expect = 2e-11
Identities = 42/124 (33%), Positives = 62/124 (50%)
Frame = -3
Query: 572 IQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPVWAF 393
+Q + L + E LRL P V++ R V ND RD+ + T V + ++A
Sbjct: 371 LQLVPLLKASIKETLRLHPISVTLQRYLV--------NDLVLRDYMIPAKTLVQVAIYAL 422
Query: 392 HRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQLLQ 213
R P FF DP FDP R+ ++K NI F L FG G R C+G R A E+ + +L+
Sbjct: 423 GREPTFFFDPENFDPTRWLSKDK-NITYFRNLGFGWGVRQCLGRRIAELEMTIFLINMLE 481
Query: 212 HMEI 201
+ +
Sbjct: 482 NFRV 485
>BC032329-1|AAH32329.1| 521|Homo sapiens cytochrome P450, family
11, subfamily A, polypeptide 1 protein.
Length = 521
Score = 68.1 bits (159), Expect = 2e-11
Identities = 42/124 (33%), Positives = 62/124 (50%)
Frame = -3
Query: 572 IQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPVWAF 393
+Q + L + E LRL P V++ R V ND RD+ + T V + ++A
Sbjct: 371 LQLVPLLKASIKETLRLHPISVTLQRYLV--------NDLVLRDYMIPAKTLVQVAIYAL 422
Query: 392 HRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQLLQ 213
R P FF DP FDP R+ ++K NI F L FG G R C+G R A E+ + +L+
Sbjct: 423 GREPTFFFDPENFDPTRWLSKDK-NITYFRNLGFGWGVRQCLGRRIAELEMTIFLINMLE 481
Query: 212 HMEI 201
+ +
Sbjct: 482 NFRV 485
>BC022539-1|AAH22539.1| 500|Homo sapiens cytochrome P450, family
46, subfamily A, polypeptide 1 protein.
Length = 500
Score = 68.1 bits (159), Expect = 2e-11
Identities = 43/128 (33%), Positives = 65/128 (50%), Gaps = 1/128 (0%)
Frame = -3
Query: 584 DYNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIP 405
D+ + + YL V+ E LRL+PP R+ ++ + D + + T +
Sbjct: 343 DFEDLGRLQYLSQVLKESLRLYPPAWGTFRLLEEETLI----DGVR----VPGNTPLLFS 394
Query: 404 VWAFHRNPEFFPDPLKFDPERFSEENKHNIKP-FAYLPFGVGPRNCIGSRFALCEVKVMA 228
+ R +F DPL F+P+RF KP F Y PF +G R+CIG +FA EVKV+
Sbjct: 395 TYVMGRMDTYFEDPLTFNPDRFGPGAP---KPRFTYFPFSLGHRSCIGQQFAQMEVKVVM 451
Query: 227 YQLLQHME 204
+LLQ +E
Sbjct: 452 AKLLQRLE 459
>AF094480-1|AAD41244.1| 500|Homo sapiens cholesterol 24-hydroxylase
protein.
Length = 500
Score = 68.1 bits (159), Expect = 2e-11
Identities = 43/128 (33%), Positives = 65/128 (50%), Gaps = 1/128 (0%)
Frame = -3
Query: 584 DYNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIP 405
D+ + + YL V+ E LRL+PP R+ ++ + D + + T +
Sbjct: 343 DFEDLGRLQYLSQVLKESLRLYPPAWGTFRLLEEETLI----DGVR----VPGNTPLLFS 394
Query: 404 VWAFHRNPEFFPDPLKFDPERFSEENKHNIKP-FAYLPFGVGPRNCIGSRFALCEVKVMA 228
+ R +F DPL F+P+RF KP F Y PF +G R+CIG +FA EVKV+
Sbjct: 395 TYVMGRMDTYFEDPLTFNPDRFGPGAP---KPRFTYFPFSLGHRSCIGQQFAQMEVKVVM 451
Query: 227 YQLLQHME 204
+LLQ +E
Sbjct: 452 AKLLQRLE 459
>AJ563379-2|CAD91649.1| 84|Homo sapiens cytochrome P450 protein.
Length = 84
Score = 67.7 bits (158), Expect = 3e-11
Identities = 28/59 (47%), Positives = 39/59 (66%)
Frame = -3
Query: 332 ENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQLLQHMEISPCEKTCIPSKLSKE 156
+ K +I P+ Y PFG GPRNCIG RFAL +K+ ++LQ+ PC++T IP KL +
Sbjct: 3 KKKDSIDPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLDTQ 61
>M32879-1|AAA52149.1| 503|Homo sapiens CYP11B1 protein.
Length = 503
Score = 66.9 bits (156), Expect = 5e-11
Identities = 34/118 (28%), Positives = 67/118 (56%)
Frame = -3
Query: 554 LDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPVWAFHRNPEF 375
L + E LRL+P G+ ++R+ D L +++ + GT V + +++ RNP
Sbjct: 365 LRAALKETLRLYPVGLFLERVASSDLVL--------QNYHIPAGTLVRVFLYSLGRNPAL 416
Query: 374 FPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQLLQHMEI 201
FP P +++P+R+ + + F ++PFG G R C+G R A E+ ++ + +L+H+++
Sbjct: 417 FPRPERYNPQRWLDIRGSG-RNFYHVPFGFGMRQCLGRRLAEAEMLLLLHHVLKHLQV 473
>BC096287-1|AAH96287.1| 503|Homo sapiens cytochrome P450, family
11, subfamily B, polypeptide 1 protein.
Length = 503
Score = 66.9 bits (156), Expect = 5e-11
Identities = 34/118 (28%), Positives = 67/118 (56%)
Frame = -3
Query: 554 LDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPVWAFHRNPEF 375
L + E LRL+P G+ ++R+ D L +++ + GT V + +++ RNP
Sbjct: 365 LRAALKETLRLYPVGLFLERVASSDLVL--------QNYHIPAGTLVRVFLYSLGRNPAL 416
Query: 374 FPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQLLQHMEI 201
FP P +++P+R+ + + F ++PFG G R C+G R A E+ ++ + +L+H+++
Sbjct: 417 FPRPERYNPQRWLDIRGSG-RNFYHVPFGFGMRQCLGRRLAEAEMLLLLHHVLKHLQV 473
>BC096285-1|AAH96285.1| 574|Homo sapiens CYP11B1 protein protein.
Length = 574
Score = 66.9 bits (156), Expect = 5e-11
Identities = 34/118 (28%), Positives = 67/118 (56%)
Frame = -3
Query: 554 LDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPVWAFHRNPEF 375
L + E LRL+P G+ ++R+ D L +++ + GT V + +++ RNP
Sbjct: 436 LRAALKETLRLYPVGLFLERVASSDLVL--------QNYHIPAGTLVRVFLYSLGRNPAL 487
Query: 374 FPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQLLQHMEI 201
FP P +++P+R+ + + F ++PFG G R C+G R A E+ ++ + +L+H+++
Sbjct: 488 FPRPERYNPQRWLDIRGSG-RNFYHVPFGFGMRQCLGRRLAEAEMLLLLHHVLKHLQV 544
>AF478474-1|AAL84813.1| 503|Homo sapiens mutated cytochrome
P-450c11 protein protein.
Length = 503
Score = 66.9 bits (156), Expect = 5e-11
Identities = 34/118 (28%), Positives = 67/118 (56%)
Frame = -3
Query: 554 LDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPVWAFHRNPEF 375
L + E LRL+P G+ ++R+ D L +++ + GT V + +++ RNP
Sbjct: 365 LRAALKETLRLYPVGLFLERVASSDLVL--------QNYHIPAGTLVRVFLYSLGRNPAL 416
Query: 374 FPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQLLQHMEI 201
FP P +++P+R+ + + F ++PFG G R C+G R A E+ ++ + +L+H+++
Sbjct: 417 FPRPERYNPQRWLDIRGSG-RNFYHVPFGFGMRQCLGRRLAEAEMLLLLHHVLKHLQV 473
>X55764-1|CAA39290.1| 503|Homo sapiens protein ( Human mRNA for
cytochrome P-450 (11 Beta). ).
Length = 503
Score = 66.5 bits (155), Expect = 7e-11
Identities = 34/118 (28%), Positives = 67/118 (56%)
Frame = -3
Query: 554 LDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPVWAFHRNPEF 375
L + E LRL+P G+ ++R+ D L +++ + GT V + +++ RNP
Sbjct: 365 LRAALKETLRLYPVGLFLERVVSSDLVL--------QNYHIPAGTLVRVFLYSLGRNPAL 416
Query: 374 FPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQLLQHMEI 201
FP P +++P+R+ + + F ++PFG G R C+G R A E+ ++ + +L+H+++
Sbjct: 417 FPRPERYNPQRWLDIRGSG-RNFYHVPFGFGMRQCLGRRLAEAEMLLLLHHVLKHLQV 473
>M63871-1|AAA59984.1| 508|Homo sapiens CYP17 protein.
Length = 508
Score = 65.7 bits (153), Expect = 1e-10
Identities = 37/98 (37%), Positives = 54/98 (55%), Gaps = 2/98 (2%)
Frame = -3
Query: 458 DKAKRDFTLRKGTGVAIPVWAFHRNPEFFPDPLKFDPERF-SEENKHNIKP-FAYLPFGV 285
D + +F + KGT V I +WA H N + + P +F PERF + I P +YLPFG
Sbjct: 378 DSSIGEFAVDKGTEVIINLWALHHNEKEWHQPDQFMPERFLNPAGTQLISPSVSYLPFGA 437
Query: 284 GPRNCIGSRFALCEVKVMAYQLLQHMEISPCEKTCIPS 171
GPR+CIG A E+ ++ LLQ ++ + +PS
Sbjct: 438 GPRSCIGEILARQELFLIMAWLLQRFDLEVPDDGQLPS 475
>M31153-1|AAA52140.1| 508|Homo sapiens CYP17 protein.
Length = 508
Score = 65.7 bits (153), Expect = 1e-10
Identities = 37/98 (37%), Positives = 54/98 (55%), Gaps = 2/98 (2%)
Frame = -3
Query: 458 DKAKRDFTLRKGTGVAIPVWAFHRNPEFFPDPLKFDPERF-SEENKHNIKP-FAYLPFGV 285
D + +F + KGT V I +WA H N + + P +F PERF + I P +YLPFG
Sbjct: 378 DSSIGEFAVDKGTEVIINLWALHHNEKEWHQPDQFMPERFLNPAGTQLISPSVSYLPFGA 437
Query: 284 GPRNCIGSRFALCEVKVMAYQLLQHMEISPCEKTCIPS 171
GPR+CIG A E+ ++ LLQ ++ + +PS
Sbjct: 438 GPRSCIGEILARQELFLIMAWLLQRFDLEVPDDGQLPS 475
>M19489-1|AAA36405.1| 508|Homo sapiens CYP17 protein.
Length = 508
Score = 65.7 bits (153), Expect = 1e-10
Identities = 37/98 (37%), Positives = 54/98 (55%), Gaps = 2/98 (2%)
Frame = -3
Query: 458 DKAKRDFTLRKGTGVAIPVWAFHRNPEFFPDPLKFDPERF-SEENKHNIKP-FAYLPFGV 285
D + +F + KGT V I +WA H N + + P +F PERF + I P +YLPFG
Sbjct: 378 DSSIGEFAVDKGTEVIINLWALHHNEKEWHQPDQFMPERFLNPAGTQLISPSVSYLPFGA 437
Query: 284 GPRNCIGSRFALCEVKVMAYQLLQHMEISPCEKTCIPS 171
GPR+CIG A E+ ++ LLQ ++ + +PS
Sbjct: 438 GPRSCIGEILARQELFLIMAWLLQRFDLEVPDDGQLPS 475
>M14564-1|AAA52151.1| 508|Homo sapiens CYP17 protein.
Length = 508
Score = 65.7 bits (153), Expect = 1e-10
Identities = 37/98 (37%), Positives = 54/98 (55%), Gaps = 2/98 (2%)
Frame = -3
Query: 458 DKAKRDFTLRKGTGVAIPVWAFHRNPEFFPDPLKFDPERF-SEENKHNIKP-FAYLPFGV 285
D + +F + KGT V I +WA H N + + P +F PERF + I P +YLPFG
Sbjct: 378 DSSIGEFAVDKGTEVIINLWALHHNEKEWHQPDQFMPERFLNPAGTQLISPSVSYLPFGA 437
Query: 284 GPRNCIGSRFALCEVKVMAYQLLQHMEISPCEKTCIPS 171
GPR+CIG A E+ ++ LLQ ++ + +PS
Sbjct: 438 GPRSCIGEILARQELFLIMAWLLQRFDLEVPDDGQLPS 475
>DQ530598-1|ABF50972.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 65.7 bits (153), Expect = 1e-10
Identities = 37/98 (37%), Positives = 54/98 (55%), Gaps = 2/98 (2%)
Frame = -3
Query: 458 DKAKRDFTLRKGTGVAIPVWAFHRNPEFFPDPLKFDPERF-SEENKHNIKP-FAYLPFGV 285
D + +F + KGT V I +WA H N + + P +F PERF + I P +YLPFG
Sbjct: 378 DSSIGEFAVDKGTEVIINLWALHHNEKEWHQPDQFMPERFLNPAGTQLISPSVSYLPFGA 437
Query: 284 GPRNCIGSRFALCEVKVMAYQLLQHMEISPCEKTCIPS 171
GPR+CIG A E+ ++ LLQ ++ + +PS
Sbjct: 438 GPRSCIGEILARQELFLIMAWLLQRFDLEVPDDGQLPS 475
>BT020000-1|AAV38803.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 65.7 bits (153), Expect = 1e-10
Identities = 37/98 (37%), Positives = 54/98 (55%), Gaps = 2/98 (2%)
Frame = -3
Query: 458 DKAKRDFTLRKGTGVAIPVWAFHRNPEFFPDPLKFDPERF-SEENKHNIKP-FAYLPFGV 285
D + +F + KGT V I +WA H N + + P +F PERF + I P +YLPFG
Sbjct: 378 DSSIGEFAVDKGTEVIINLWALHHNEKEWHQPDQFMPERFLNPAGTQLISPSVSYLPFGA 437
Query: 284 GPRNCIGSRFALCEVKVMAYQLLQHMEISPCEKTCIPS 171
GPR+CIG A E+ ++ LLQ ++ + +PS
Sbjct: 438 GPRSCIGEILARQELFLIMAWLLQRFDLEVPDDGQLPS 475
>BC063388-1|AAH63388.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 65.7 bits (153), Expect = 1e-10
Identities = 37/98 (37%), Positives = 54/98 (55%), Gaps = 2/98 (2%)
Frame = -3
Query: 458 DKAKRDFTLRKGTGVAIPVWAFHRNPEFFPDPLKFDPERF-SEENKHNIKP-FAYLPFGV 285
D + +F + KGT V I +WA H N + + P +F PERF + I P +YLPFG
Sbjct: 378 DSSIGEFAVDKGTEVIINLWALHHNEKEWHQPDQFMPERFLNPAGTQLISPSVSYLPFGA 437
Query: 284 GPRNCIGSRFALCEVKVMAYQLLQHMEISPCEKTCIPS 171
GPR+CIG A E+ ++ LLQ ++ + +PS
Sbjct: 438 GPRSCIGEILARQELFLIMAWLLQRFDLEVPDDGQLPS 475
>BC062997-1|AAH62997.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 65.7 bits (153), Expect = 1e-10
Identities = 37/98 (37%), Positives = 54/98 (55%), Gaps = 2/98 (2%)
Frame = -3
Query: 458 DKAKRDFTLRKGTGVAIPVWAFHRNPEFFPDPLKFDPERF-SEENKHNIKP-FAYLPFGV 285
D + +F + KGT V I +WA H N + + P +F PERF + I P +YLPFG
Sbjct: 378 DSSIGEFAVDKGTEVIINLWALHHNEKEWHQPDQFMPERFLNPAGTQLISPSVSYLPFGA 437
Query: 284 GPRNCIGSRFALCEVKVMAYQLLQHMEISPCEKTCIPS 171
GPR+CIG A E+ ++ LLQ ++ + +PS
Sbjct: 438 GPRSCIGEILARQELFLIMAWLLQRFDLEVPDDGQLPS 475
>AL358790-3|CAI52498.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 65.7 bits (153), Expect = 1e-10
Identities = 37/98 (37%), Positives = 54/98 (55%), Gaps = 2/98 (2%)
Frame = -3
Query: 458 DKAKRDFTLRKGTGVAIPVWAFHRNPEFFPDPLKFDPERF-SEENKHNIKP-FAYLPFGV 285
D + +F + KGT V I +WA H N + + P +F PERF + I P +YLPFG
Sbjct: 378 DSSIGEFAVDKGTEVIINLWALHHNEKEWHQPDQFMPERFLNPAGTQLISPSVSYLPFGA 437
Query: 284 GPRNCIGSRFALCEVKVMAYQLLQHMEISPCEKTCIPS 171
GPR+CIG A E+ ++ LLQ ++ + +PS
Sbjct: 438 GPRSCIGEILARQELFLIMAWLLQRFDLEVPDDGQLPS 475
>AL358613-3|CAH72804.1| 428|Homo sapiens cytochrome P450, family
26, subfamily A, polypeptide 1 protein.
Length = 428
Score = 63.7 bits (148), Expect = 5e-10
Identities = 34/127 (26%), Positives = 62/127 (48%)
Frame = -3
Query: 584 DYNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIP 405
D ++ + Y+ V+ E LRL PP R+ ++ + L + + KG V
Sbjct: 277 DMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELN--------GYQIPKGWNVIYS 328
Query: 404 VWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAY 225
+ H E F + +F+P+RF + + F+++PFG G R+C+G FA +K+
Sbjct: 329 ICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTV 388
Query: 224 QLLQHME 204
+L +H +
Sbjct: 389 ELARHCD 395
>AL358613-2|CAH72803.1| 497|Homo sapiens cytochrome P450, family
26, subfamily A, polypeptide 1 protein.
Length = 497
Score = 63.7 bits (148), Expect = 5e-10
Identities = 34/127 (26%), Positives = 62/127 (48%)
Frame = -3
Query: 584 DYNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIP 405
D ++ + Y+ V+ E LRL PP R+ ++ + L + + KG V
Sbjct: 346 DMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELN--------GYQIPKGWNVIYS 397
Query: 404 VWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAY 225
+ H E F + +F+P+RF + + F+++PFG G R+C+G FA +K+
Sbjct: 398 ICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTV 457
Query: 224 QLLQHME 204
+L +H +
Sbjct: 458 ELARHCD 464
>AF005418-1|AAB88881.1| 497|Homo sapiens retinoic acid hydroxylase
protein.
Length = 497
Score = 63.7 bits (148), Expect = 5e-10
Identities = 34/127 (26%), Positives = 62/127 (48%)
Frame = -3
Query: 584 DYNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIP 405
D ++ + Y+ V+ E LRL PP R+ ++ + L + + KG V
Sbjct: 346 DMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELN--------GYQIPKGWNVIYS 397
Query: 404 VWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAY 225
+ H E F + +F+P+RF + + F+++PFG G R+C+G FA +K+
Sbjct: 398 ICDTHDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTV 457
Query: 224 QLLQHME 204
+L +H +
Sbjct: 458 ELARHCD 464
>AK090886-1|BAC03539.1| 337|Homo sapiens protein ( Homo sapiens
cDNA FLJ33567 fis, clone BRAMY2010272, highly similar to
Homo sapiens cholesterol 24-hydroxylase mRNA. ).
Length = 337
Score = 63.3 bits (147), Expect = 6e-10
Identities = 44/128 (34%), Positives = 62/128 (48%), Gaps = 1/128 (0%)
Frame = -3
Query: 584 DYNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIP 405
D+ + + YL V+ E LRL+PP R+ ++ TL G
Sbjct: 190 DFEDLGRLQYLSQVLKESLRLYPPAWGTFRLLEEE--------------TLIDG----FS 231
Query: 404 VWAFHRNPEFFPDPLKFDPERFSEENKHNIKP-FAYLPFGVGPRNCIGSRFALCEVKVMA 228
+ R +F DPL F+P+RF KP F Y PF +G R+CIG +FA EVKV+
Sbjct: 232 TYVMGRMDTYFEDPLTFNPDRFGPGAP---KPRFTYFPFSLGHRSCIGQQFAQMEVKVVM 288
Query: 227 YQLLQHME 204
+LLQ +E
Sbjct: 289 AKLLQRLE 296
>BC039307-1|AAH39307.1| 372|Homo sapiens cytochrome P450, family
27, subfamily C, polypeptide 1 protein.
Length = 372
Score = 62.9 bits (146), Expect = 8e-10
Identities = 44/140 (31%), Positives = 68/140 (48%), Gaps = 1/140 (0%)
Frame = -3
Query: 545 VVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPVWAFHRNPEFFPD 366
++ E LRL+P R+ +D +G + + KGT +A+ +A E FP
Sbjct: 234 LLKETLRLFPVLPGNGRVTQEDLVIG--------GYLIPKGTQLALCHYATSYQDENFPR 285
Query: 365 PLKFDPERFSEENK-HNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQLLQHMEISPCE 189
+F PER+ + + F +PFG G R+CIG R A E+ ++ QLLQH EI
Sbjct: 286 AKEFRPERWLRKGDLDRVDNFGSIPFGHGVRSCIGRRIAELEIHLVVIQLLQHFEIKTSS 345
Query: 188 KTCIPSKLSKETFNLRLEGG 129
+T + + +T L GG
Sbjct: 346 QT---NAVHAKTHGLLTPGG 362
>AK131190-1|BAD18388.1| 372|Homo sapiens .-.-). protein.
Length = 372
Score = 62.9 bits (146), Expect = 8e-10
Identities = 44/140 (31%), Positives = 68/140 (48%), Gaps = 1/140 (0%)
Frame = -3
Query: 545 VVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPVWAFHRNPEFFPD 366
++ E LRL+P R+ +D +G + + KGT +A+ +A E FP
Sbjct: 234 LLKETLRLFPVLPGNGRVTQEDLVIG--------GYLIPKGTQLALCHYATSYQDENFPR 285
Query: 365 PLKFDPERFSEENK-HNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQLLQHMEISPCE 189
+F PER+ + + F +PFG G R+CIG R A E+ ++ QLLQH EI
Sbjct: 286 AKEFRPERWLRKGDLDRVDNFGSIPFGHGVRSCIGRRIAELEIHLVVIQLLQHFEIKTSS 345
Query: 188 KTCIPSKLSKETFNLRLEGG 129
+T + + +T L GG
Sbjct: 346 QT---NAVHAKTHGLLTPGG 362
>BC132767-1|AAI32768.1| 544|Homo sapiens cytochrome P450, family 2,
subfamily U, polypeptide 1 protein.
Length = 544
Score = 61.7 bits (143), Expect = 2e-09
Identities = 27/76 (35%), Positives = 44/76 (57%)
Frame = -3
Query: 440 FTLRKGTGVAIPVWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGS 261
+T+ KGT + +W+ HR+P + P F P RF ++ IK ++PFG+G R C+G
Sbjct: 434 YTIPKGTLILPNLWSVHRDPAIWEKPEDFYPNRFLDDQGQLIKKETFIPFGIGKRVCMGE 493
Query: 260 RFALCEVKVMAYQLLQ 213
+ A E+ +M L+Q
Sbjct: 494 QLAKMELFLMFVSLMQ 509
>AY343323-1|AAQ21380.1| 544|Homo sapiens cytochrome P450 protein.
Length = 544
Score = 61.7 bits (143), Expect = 2e-09
Identities = 27/76 (35%), Positives = 44/76 (57%)
Frame = -3
Query: 440 FTLRKGTGVAIPVWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGS 261
+T+ KGT + +W+ HR+P + P F P RF ++ IK ++PFG+G R C+G
Sbjct: 434 YTIPKGTLILPNLWSVHRDPAIWEKPEDFYPNRFLDDQGQLIKKETFIPFGIGKRVCMGE 493
Query: 260 RFALCEVKVMAYQLLQ 213
+ A E+ +M L+Q
Sbjct: 494 QLAKMELFLMFVSLMQ 509
>BC109205-1|AAI09206.1| 512|Homo sapiens cytochrome P450, family
26, subfamily B, polypeptide 1 protein.
Length = 512
Score = 60.9 bits (141), Expect = 3e-09
Identities = 39/121 (32%), Positives = 58/121 (47%), Gaps = 1/121 (0%)
Frame = -3
Query: 578 NSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPVW 399
+++ + YLD V+ E++RL+ P R +Q + L F + KG V +
Sbjct: 346 DTLSGLRYLDCVIKEVMRLFTPISGGYRTVLQTFELD--------GFQIPKGWSVMYSIR 397
Query: 398 AFHRNPEFFPDPLKFDPERFSEENKHNIKP-FAYLPFGVGPRNCIGSRFALCEVKVMAYQ 222
H F D FDP+RFS+ + F YLPFG G R C+G A +KV+A +
Sbjct: 398 DTHDTAPVFKDVNVFDPDRFSQARSEDKDGRFHYLPFGGGVRTCLGKHLAKLFLKVLAVE 457
Query: 221 L 219
L
Sbjct: 458 L 458
>BC069443-1|AAH69443.1| 512|Homo sapiens cytochrome P450, family
26, subfamily B, polypeptide 1 protein.
Length = 512
Score = 60.9 bits (141), Expect = 3e-09
Identities = 39/121 (32%), Positives = 58/121 (47%), Gaps = 1/121 (0%)
Frame = -3
Query: 578 NSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPVW 399
+++ + YLD V+ E++RL+ P R +Q + L F + KG V +
Sbjct: 346 DTLSGLRYLDCVIKEVMRLFTPISGGYRTVLQTFELD--------GFQIPKGWSVMYSIR 397
Query: 398 AFHRNPEFFPDPLKFDPERFSEENKHNIKP-FAYLPFGVGPRNCIGSRFALCEVKVMAYQ 222
H F D FDP+RFS+ + F YLPFG G R C+G A +KV+A +
Sbjct: 398 DTHDTAPVFKDVNVFDPDRFSQARSEDKDGRFHYLPFGGGVRTCLGKHLAKLFLKVLAVE 457
Query: 221 L 219
L
Sbjct: 458 L 458
>BC032322-1|AAH32322.1| 509|Homo sapiens cytochrome P450, family
51, subfamily A, polypeptide 1 protein.
Length = 509
Score = 60.9 bits (141), Expect = 3e-09
Identities = 37/126 (29%), Positives = 64/126 (50%)
Frame = -3
Query: 581 YNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPV 402
Y+ ++++ LD + E LRL PP + M R+ P A +T+ G V +
Sbjct: 360 YDQLKDLNLLDRCIKETLRLRPPVMIMMRMA------RTPQTVA--GYTIPPGHQVCVSP 411
Query: 401 WAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQ 222
R + + + L F+P+R+ ++N + + FAY+PFG G CIG FA ++K +
Sbjct: 412 TVNQRLKDSWVERLDFNPDRYLQDNPASGEKFAYVPFGAGRHRCIGENFAYVQIKTIWST 471
Query: 221 LLQHME 204
+L+ E
Sbjct: 472 MLRLYE 477
>AF252297-1|AAF76003.1| 512|Homo sapiens cytochrome P450 retinoid
metabolizing protein P450RAI-2 protein.
Length = 512
Score = 60.9 bits (141), Expect = 3e-09
Identities = 39/121 (32%), Positives = 58/121 (47%), Gaps = 1/121 (0%)
Frame = -3
Query: 578 NSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPVW 399
+++ + YLD V+ E++RL+ P R +Q + L F + KG V +
Sbjct: 346 DTLSGLRYLDCVIKEVMRLFTPISGGYRTVLQTFELD--------GFQIPKGWSVMYSIR 397
Query: 398 AFHRNPEFFPDPLKFDPERFSEENKHNIKP-FAYLPFGVGPRNCIGSRFALCEVKVMAYQ 222
H F D FDP+RFS+ + F YLPFG G R C+G A +KV+A +
Sbjct: 398 DTHDTAPVFKDVNVFDPDRFSQARSEDKDGRFHYLPFGGGVRTCLGKHLAKLFLKVLAVE 457
Query: 221 L 219
L
Sbjct: 458 L 458
>AC007002-1|AAY14690.1| 512|Homo sapiens unknown protein.
Length = 512
Score = 60.9 bits (141), Expect = 3e-09
Identities = 39/121 (32%), Positives = 58/121 (47%), Gaps = 1/121 (0%)
Frame = -3
Query: 578 NSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPVW 399
+++ + YLD V+ E++RL+ P R +Q + L F + KG V +
Sbjct: 346 DTLSGLRYLDCVIKEVMRLFTPISGGYRTVLQTFELD--------GFQIPKGWSVMYSIR 397
Query: 398 AFHRNPEFFPDPLKFDPERFSEENKHNIKP-FAYLPFGVGPRNCIGSRFALCEVKVMAYQ 222
H F D FDP+RFS+ + F YLPFG G R C+G A +KV+A +
Sbjct: 398 DTHDTAPVFKDVNVFDPDRFSQARSEDKDGRFHYLPFGGGVRTCLGKHLAKLFLKVLAVE 457
Query: 221 L 219
L
Sbjct: 458 L 458
>X54741-1|CAA38539.1| 503|Homo sapiens aldosterone synthase
(P-450aldo) protein.
Length = 503
Score = 60.5 bits (140), Expect = 4e-09
Identities = 33/115 (28%), Positives = 63/115 (54%)
Frame = -3
Query: 554 LDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPVWAFHRNPEF 375
L + E LRL+P G+ ++R+ D L +++ + GT V + +++ RN
Sbjct: 365 LRAALKETLRLYPVGLFLERVVSSDLVL--------QNYHIPAGTLVQVFLYSLGRNAAL 416
Query: 374 FPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQLLQH 210
FP P +++P+R+ + + F ++PFG G R C+G R A E+ ++ + +L+H
Sbjct: 417 FPRPERYNPQRWLDIRGSG-RNFHHVPFGFGMRQCLGRRLAEAEMLLLLHHVLKH 470
>U23942-1|AAB39951.1| 509|Homo sapiens lanosterol 14-demethylase
cytochrome P450 protein.
Length = 509
Score = 60.5 bits (140), Expect = 4e-09
Identities = 37/126 (29%), Positives = 64/126 (50%)
Frame = -3
Query: 581 YNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPV 402
Y+ ++++ LD + E LRL PP + M R+ P A +T+ G V +
Sbjct: 360 YDQLKDLNLLDRCIKETLRLRPPIMIMMRMA------RTPQTVA--GYTIPPGHQVCVSP 411
Query: 401 WAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQ 222
R + + + L F+P+R+ ++N + + FAY+PFG G CIG FA ++K +
Sbjct: 412 TVNQRLKDSWVERLDFNPDRYLQDNPASGEKFAYVPFGAGRHRCIGENFAYVQIKTIWST 471
Query: 221 LLQHME 204
+L+ E
Sbjct: 472 MLRLYE 477
>D55653-1|BAA09512.1| 509|Homo sapiens lanosterol 14-demethylase
protein.
Length = 509
Score = 60.5 bits (140), Expect = 4e-09
Identities = 37/126 (29%), Positives = 64/126 (50%)
Frame = -3
Query: 581 YNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPV 402
Y+ ++++ LD + E LRL PP + M R+ P A +T+ G V +
Sbjct: 360 YDQLKDLNLLDRCIKETLRLRPPIMIMMRMA------RTPQTVA--GYTIPPGHQVCVSP 411
Query: 401 WAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQ 222
R + + + L F+P+R+ ++N + + FAY+PFG G CIG FA ++K +
Sbjct: 412 TVNQRLKDSWVERLDFNPDRYLQDNPASGEKFAYVPFGAGRHRCIGENFAYVQIKTIWST 471
Query: 221 LLQHME 204
+L+ E
Sbjct: 472 MLRLYE 477
>D13752-1|BAA02899.1| 503|Homo sapiens steroid 18-hydroxylase
protein.
Length = 503
Score = 60.5 bits (140), Expect = 4e-09
Identities = 33/115 (28%), Positives = 63/115 (54%)
Frame = -3
Query: 554 LDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPVWAFHRNPEF 375
L + E LRL+P G+ ++R+ D L +++ + GT V + +++ RN
Sbjct: 365 LRAALKETLRLYPVGLFLERVVSSDLVL--------QNYHIPAGTLVQVFLYSLGRNAAL 416
Query: 374 FPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQLLQH 210
FP P +++P+R+ + + F ++PFG G R C+G R A E+ ++ + +L+H
Sbjct: 417 FPRPERYNPQRWLDIRGSG-RNFHHVPFGFGMRQCLGRRLAEAEMLLLLHHVLKH 470
>AC000120-2|AAB46356.1| 509|Homo sapiens unknown protein.
Length = 509
Score = 60.5 bits (140), Expect = 4e-09
Identities = 37/126 (29%), Positives = 64/126 (50%)
Frame = -3
Query: 581 YNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPV 402
Y+ ++++ LD + E LRL PP + M R+ P A +T+ G V +
Sbjct: 360 YDQLKDLNLLDRCIKETLRLRPPIMIMMRMA------RTPQTVA--GYTIPPGHQVCVSP 411
Query: 401 WAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQ 222
R + + + L F+P+R+ ++N + + FAY+PFG G CIG FA ++K +
Sbjct: 412 TVNQRLKDSWVERLDFNPDRYLQDNPASGEKFAYVPFGAGRHRCIGENFAYVQIKTIWST 471
Query: 221 LLQHME 204
+L+ E
Sbjct: 472 MLRLYE 477
>U51692-1|AAC50951.1| 503|Homo sapiens lanosterol 14-alpha
demethylase protein.
Length = 503
Score = 60.1 bits (139), Expect = 6e-09
Identities = 37/126 (29%), Positives = 64/126 (50%)
Frame = -3
Query: 581 YNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPV 402
Y+ ++++ LD + E LRL PP + M R+ P A +T+ G V +
Sbjct: 354 YDQLKDLNLLDRCIRETLRLRPPIMIMMRMA------RTPQTVA--GYTIPPGHQVCVSP 405
Query: 401 WAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQ 222
R + + + L F+P+R+ ++N + + FAY+PFG G CIG FA ++K +
Sbjct: 406 TVNQRLKDSWVERLDFNPDRYLQDNPASGEKFAYVPFGAGRHRCIGENFAYVQIKTIWST 465
Query: 221 LLQHME 204
+L+ E
Sbjct: 466 MLRLYE 471
>S67623-1|AAB29308.1| 257|Homo sapiens 25-hydroxyvitamin D
24-hydroxylase cytochrome P450 subunit protein.
Length = 257
Score = 60.1 bits (139), Expect = 6e-09
Identities = 40/124 (32%), Positives = 62/124 (50%)
Frame = -3
Query: 572 IQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPVWAF 393
++NM YL + E +RL P R + LG ++ L KGT + +
Sbjct: 114 LRNMPYLKACLKESMRLTPSVPFTTRTLDKATVLG--------EYALPKGTVLMLNTQVL 165
Query: 392 HRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQLLQ 213
+ + F D +F PER+ +E K I PFA+LPFGVG R CIG R A ++ + +++
Sbjct: 166 GSSEDNFEDSSQFRPERWLQE-KEKINPFAHLPFGVGKRMCIGRRLAELQLHLALCWIVR 224
Query: 212 HMEI 201
+I
Sbjct: 225 KYDI 228
>AY858838-1|AAW50795.1| 372|Homo sapiens vitamin D 24-hydroxylase
splice variant protein.
Length = 372
Score = 60.1 bits (139), Expect = 6e-09
Identities = 40/124 (32%), Positives = 62/124 (50%)
Frame = -3
Query: 572 IQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPVWAF 393
++NM YL + E +RL P R + LG ++ L KGT + +
Sbjct: 229 LRNMPYLKACLKESMRLTPSVPFTTRTLDKATVLG--------EYALPKGTVLMLNTQVL 280
Query: 392 HRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQLLQ 213
+ + F D +F PER+ +E K I PFA+LPFGVG R CIG R A ++ + +++
Sbjct: 281 GSSEDNFEDSSQFRPERWLQE-KEKINPFAHLPFGVGKRMCIGRRLAELQLHLALCWIVR 339
Query: 212 HMEI 201
+I
Sbjct: 340 KYDI 343
>AL138805-2|CAB91829.1| 514|Homo sapiens cytochrome P450, family
24, subfamily A, polypeptide 1 protein.
Length = 514
Score = 60.1 bits (139), Expect = 6e-09
Identities = 40/124 (32%), Positives = 62/124 (50%)
Frame = -3
Query: 572 IQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPVWAF 393
++NM YL + E +RL P R + LG ++ L KGT + +
Sbjct: 371 LRNMPYLKACLKESMRLTPSVPFTTRTLDKATVLG--------EYALPKGTVLMLNTQVL 422
Query: 392 HRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQLLQ 213
+ + F D +F PER+ +E K I PFA+LPFGVG R CIG R A ++ + +++
Sbjct: 423 GSSEDNFEDSSQFRPERWLQE-KEKINPFAHLPFGVGKRMCIGRRLAELQLHLALCWIVR 481
Query: 212 HMEI 201
+I
Sbjct: 482 KYDI 485
>AL138805-1|CAM27342.1| 372|Homo sapiens cytochrome P450, family
24, subfamily A, polypeptide 1 protein.
Length = 372
Score = 60.1 bits (139), Expect = 6e-09
Identities = 40/124 (32%), Positives = 62/124 (50%)
Frame = -3
Query: 572 IQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPVWAF 393
++NM YL + E +RL P R + LG ++ L KGT + +
Sbjct: 229 LRNMPYLKACLKESMRLTPSVPFTTRTLDKATVLG--------EYALPKGTVLMLNTQVL 280
Query: 392 HRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQLLQ 213
+ + F D +F PER+ +E K I PFA+LPFGVG R CIG R A ++ + +++
Sbjct: 281 GSSEDNFEDSSQFRPERWLQE-KEKINPFAHLPFGVGKRMCIGRRLAELQLHLALCWIVR 339
Query: 212 HMEI 201
+I
Sbjct: 340 KYDI 343
>X71480-1|CAA50586.1| 141|Homo sapiens cytochrome P450 protein.
Length = 141
Score = 59.7 bits (138), Expect = 8e-09
Identities = 34/104 (32%), Positives = 52/104 (50%)
Frame = -3
Query: 581 YNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPV 402
+N + M Y M + E LRL+PP + R P+ ++ L KG V + +
Sbjct: 47 WNHLDQMPYTTMCIKEALRLYPPVPGISRELSTPVTF--PDGRS-----LPKGITVMLSI 99
Query: 401 WAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNC 270
+ H NP+ +P+P FDP RF+ + + A+LPF G RNC
Sbjct: 100 YGLHHNPKVWPNPEVFDPSRFAPGSAQH--SHAFLPFSGGSRNC 141
>L13286-1|AAA62379.1| 513|Homo sapiens 1,25-dihydroxyvitamin D3
24-hydroxylase protein.
Length = 513
Score = 59.7 bits (138), Expect = 8e-09
Identities = 40/124 (32%), Positives = 62/124 (50%)
Frame = -3
Query: 572 IQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPVWAF 393
++NM YL + E +RL P R + LG ++ L KGT + +
Sbjct: 370 LRNMPYLKACLKESMRLTPGVPFTTRTLDKATVLG--------EYALPKGTVLMLNTQVL 421
Query: 392 HRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQLLQ 213
+ + F D +F PER+ +E K I PFA+LPFGVG R CIG R A ++ + +++
Sbjct: 422 GSSEDNFEDSSQFRPERWLQE-KEKINPFAHLPFGVGKRMCIGRRLAELQLHLALCWIVR 480
Query: 212 HMEI 201
+I
Sbjct: 481 KYDI 484
>BC100982-1|AAI00983.1| 280|Homo sapiens CYP3A43 protein protein.
Length = 280
Score = 59.3 bits (137), Expect = 1e-08
Identities = 29/80 (36%), Positives = 47/80 (58%)
Frame = -3
Query: 581 YNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPV 402
Y+++ M YLDMVV+E LRL+P + R+C +D + + KG V +P+
Sbjct: 207 YDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEI--------NGVFIPKGLAVMVPI 258
Query: 401 WAFHRNPEFFPDPLKFDPER 342
+A H +P+++ +P KF PER
Sbjct: 259 YALHHDPKYWTEPEKFCPER 278
>AF280110-1|AAG33011.1| 420|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 420
Score = 59.3 bits (137), Expect = 1e-08
Identities = 29/80 (36%), Positives = 47/80 (58%)
Frame = -3
Query: 581 YNSIQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPV 402
Y+++ M YLDMVV+E LRL+P + R+C +D + + KG V +P+
Sbjct: 347 YDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEI--------NGVFIPKGLAVMVPI 398
Query: 401 WAFHRNPEFFPDPLKFDPER 342
+A H +P+++ +P KF PER
Sbjct: 399 YALHHDPKYWTEPEKFCPER 418
>X13930-1|CAA32118.1| 494|Homo sapiens protein ( Human CYP2A4 mRNA
for P-450 IIA4 protein. ).
Length = 494
Score = 58.8 bits (136), Expect = 1e-08
Identities = 30/86 (34%), Positives = 45/86 (52%)
Frame = -3
Query: 458 DKAKRDFTLRKGTGVAIPVWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGP 279
D RDF L KGT V + + R+P FF +P F+P+ F E K A++PF +G
Sbjct: 377 DTKFRDFFLPKGTEVYPMLGSVLRDPSFFSNPQDFNPQHFLNEKGQFKKSDAFVPFSIGK 436
Query: 278 RNCIGSRFALCEVKVMAYQLLQHMEI 201
RNC G A E+ + ++Q+ +
Sbjct: 437 RNCFGEGLARMELFLFFTTVMQNFRL 462
>X13929-1|CAA32117.1| 448|Homo sapiens P-450 IIA3 protein (1 is 3rd
base in codon) protein.
Length = 448
Score = 58.8 bits (136), Expect = 1e-08
Identities = 30/86 (34%), Positives = 45/86 (52%)
Frame = -3
Query: 458 DKAKRDFTLRKGTGVAIPVWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGP 279
D RDF L KGT V + + R+P FF +P F+P+ F E K A++PF +G
Sbjct: 331 DTKFRDFFLPKGTEVYPMLGSVLRDPSFFSNPQDFNPQHFLNEKGQFKKSDAFVPFSIGK 390
Query: 278 RNCIGSRFALCEVKVMAYQLLQHMEI 201
RNC G A E+ + ++Q+ +
Sbjct: 391 RNCFGEGLARMELFLFFTTVMQNFRL 416
>X13897-1|CAA32097.1| 489|Homo sapiens protein ( Human mRNA for
cytochrome P-450IIA. ).
Length = 489
Score = 58.8 bits (136), Expect = 1e-08
Identities = 30/86 (34%), Positives = 45/86 (52%)
Frame = -3
Query: 458 DKAKRDFTLRKGTGVAIPVWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGP 279
D RDF L KGT V + + R+P FF +P F+P+ F E K A++PF +G
Sbjct: 372 DTKFRDFFLPKGTEVYPMLGSVLRDPSFFSNPQDFNPQHFLNEKGQFKKSDAFVPFSIGK 431
Query: 278 RNCIGSRFALCEVKVMAYQLLQHMEI 201
RNC G A E+ + ++Q+ +
Sbjct: 432 RNCFGEGLARMELFLFFTTVMQNFRL 457
>M33318-1|AAA52067.1| 494|Homo sapiens CYP2A protein.
Length = 494
Score = 58.8 bits (136), Expect = 1e-08
Identities = 30/86 (34%), Positives = 45/86 (52%)
Frame = -3
Query: 458 DKAKRDFTLRKGTGVAIPVWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGP 279
D RDF L KGT V + + R+P FF +P F+P+ F E K A++PF +G
Sbjct: 377 DTKFRDFFLPKGTEVYPMLGSVLRDPSFFSNPQDFNPQHFLNEKGQFKKSDAFVPFSIGK 436
Query: 278 RNCIGSRFALCEVKVMAYQLLQHMEI 201
RNC G A E+ + ++Q+ +
Sbjct: 437 RNCFGEGLARMELFLFFTTVMQNFRL 462
>BC096256-1|AAH96256.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 58.8 bits (136), Expect = 1e-08
Identities = 30/86 (34%), Positives = 45/86 (52%)
Frame = -3
Query: 458 DKAKRDFTLRKGTGVAIPVWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGP 279
D RDF L KGT V + + R+P FF +P F+P+ F E K A++PF +G
Sbjct: 377 DTKFRDFFLPKGTEVYPMLGSVLRDPSFFSNPQDFNPQHFLNEKGQFKKSDAFVPFSIGK 436
Query: 278 RNCIGSRFALCEVKVMAYQLLQHMEI 201
RNC G A E+ + ++Q+ +
Sbjct: 437 RNCFGEGLARMELFLFFTTVMQNFRL 462
>BC096255-1|AAH96255.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 58.8 bits (136), Expect = 1e-08
Identities = 30/86 (34%), Positives = 45/86 (52%)
Frame = -3
Query: 458 DKAKRDFTLRKGTGVAIPVWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGP 279
D RDF L KGT V + + R+P FF +P F+P+ F E K A++PF +G
Sbjct: 377 DTKFRDFFLPKGTEVYPMLGSVLRDPSFFSNPQDFNPQHFLNEKGQFKKSDAFVPFSIGK 436
Query: 278 RNCIGSRFALCEVKVMAYQLLQHMEI 201
RNC G A E+ + ++Q+ +
Sbjct: 437 RNCFGEGLARMELFLFFTTVMQNFRL 462
>BC096254-1|AAH96254.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 58.8 bits (136), Expect = 1e-08
Identities = 30/86 (34%), Positives = 45/86 (52%)
Frame = -3
Query: 458 DKAKRDFTLRKGTGVAIPVWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGP 279
D RDF L KGT V + + R+P FF +P F+P+ F E K A++PF +G
Sbjct: 377 DTKFRDFFLPKGTEVYPMLGSVLRDPSFFSNPQDFNPQHFLNEKGQFKKSDAFVPFSIGK 436
Query: 278 RNCIGSRFALCEVKVMAYQLLQHMEI 201
RNC G A E+ + ++Q+ +
Sbjct: 437 RNCFGEGLARMELFLFFTTVMQNFRL 462
>BC096253-1|AAH96253.3| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 58.8 bits (136), Expect = 1e-08
Identities = 30/86 (34%), Positives = 45/86 (52%)
Frame = -3
Query: 458 DKAKRDFTLRKGTGVAIPVWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGP 279
D RDF L KGT V + + R+P FF +P F+P+ F E K A++PF +G
Sbjct: 377 DTKFRDFFLPKGTEVYPMLGSVLRDPSFFSNPQDFNPQHFLNEKGQFKKSDAFVPFSIGK 436
Query: 278 RNCIGSRFALCEVKVMAYQLLQHMEI 201
RNC G A E+ + ++Q+ +
Sbjct: 437 RNCFGEGLARMELFLFFTTVMQNFRL 462
>AF182275-1|AAF13600.1| 494|Homo sapiens cytochrome P450-2A6
protein.
Length = 494
Score = 58.8 bits (136), Expect = 1e-08
Identities = 30/86 (34%), Positives = 45/86 (52%)
Frame = -3
Query: 458 DKAKRDFTLRKGTGVAIPVWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGP 279
D RDF L KGT V + + R+P FF +P F+P+ F E K A++PF +G
Sbjct: 377 DTKFRDFFLPKGTEVYPMLGSVLRDPSFFSNPQDFNPQHFLNEKGQFKKSDAFVPFSIGK 436
Query: 278 RNCIGSRFALCEVKVMAYQLLQHMEI 201
RNC G A E+ + ++Q+ +
Sbjct: 437 RNCFGEGLARMELFLFFTTVMQNFRL 462
>M24667-1|AAA52148.1| 256|Homo sapiens steroid 11-beta-hydroxylase
protein.
Length = 256
Score = 58.4 bits (135), Expect = 2e-08
Identities = 36/115 (31%), Positives = 64/115 (55%)
Frame = -3
Query: 554 LDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPVWAFHRNPEF 375
L + E LRL+P G+ ++R+ D L +++ + GT V + +++ RNP
Sbjct: 155 LRAALKETLRLYPVGLILERVVSSDLVL--------QNYHIPAGTLVRVFLYSLGRNPAL 206
Query: 374 FPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQLLQH 210
FP P +++P+R+ + K + + F ++PFG G R C+G R A ++ + LLQH
Sbjct: 207 FPRPERYNPQRWL-DIKGSGRNFYHVPFGFGMRQCLGRRLAEADMLL----LLQH 256
>M93133-1|AAA58435.1| 504|Homo sapiens cholesterol 7-alpha
hydroxylase protein.
Length = 504
Score = 56.8 bits (131), Expect = 5e-08
Identities = 38/137 (27%), Positives = 67/137 (48%), Gaps = 9/137 (6%)
Frame = -3
Query: 572 IQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPVWAF 393
+ ++ LD ++ E LRL +++ R +D+ L + + +RK +A+
Sbjct: 340 LNDLPVLDSIIKESLRLSSASLNI-RTAKEDFTLHLEDGS----YNIRKDDIIALYPQLM 394
Query: 392 HRNPEFFPDPLKFDPERFSEENK--------HNIK-PFAYLPFGVGPRNCIGSRFALCEV 240
H +PE +PDPL F +R+ +EN + +K + Y+PFG G C G FA+ E+
Sbjct: 395 HLDPEIYPDPLTFKYDRYLDENGKTKTTFYCNGLKLKYYYMPFGSGATICPGRLFAIHEI 454
Query: 239 KVMAYQLLQHMEISPCE 189
K +L + E+ E
Sbjct: 455 KQFLILMLSYFELELIE 471
>EF122241-1|ABO41976.1| 491|Homo sapiens cytochrome P450 2F1
variant protein.
Length = 491
Score = 56.8 bits (131), Expect = 5e-08
Identities = 30/88 (34%), Positives = 44/88 (50%)
Frame = -3
Query: 458 DKAKRDFTLRKGTGVAIPVWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGP 279
D A R F + KGT V + H +P F P +F+PE F + N+ K A++PF G
Sbjct: 374 DTAFRGFLIPKGTDVITLLNTVHYDPSQFLTPQEFNPEHFLDANQSFKKSPAFMPFSAGR 433
Query: 278 RNCIGSRFALCEVKVMAYQLLQHMEISP 195
R C+G A E+ + +LQ + P
Sbjct: 434 RLCLGESLARMELFLYLTAILQSFSLQP 461
>BC112184-1|AAI12185.1| 504|Homo sapiens cytochrome P450, family 7,
subfamily A, polypeptide 1 protein.
Length = 504
Score = 56.8 bits (131), Expect = 5e-08
Identities = 38/137 (27%), Positives = 67/137 (48%), Gaps = 9/137 (6%)
Frame = -3
Query: 572 IQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPVWAF 393
+ ++ LD ++ E LRL +++ R +D+ L + + +RK +A+
Sbjct: 340 LNDLPVLDSIIKESLRLSSASLNI-RTAKEDFTLHLEDGS----YNIRKDDIIALYPQLM 394
Query: 392 HRNPEFFPDPLKFDPERFSEENK--------HNIK-PFAYLPFGVGPRNCIGSRFALCEV 240
H +PE +PDPL F +R+ +EN + +K + Y+PFG G C G FA+ E+
Sbjct: 395 HLDPEIYPDPLTFKYDRYLDENGKTKTTFYCNGLKLKYYYMPFGSGATICPGRLFAIHEI 454
Query: 239 KVMAYQLLQHMEISPCE 189
K +L + E+ E
Sbjct: 455 KQFLILMLSYFELELIE 471
>BC101777-1|AAI01778.1| 504|Homo sapiens cytochrome P450, family 7,
subfamily A, polypeptide 1 protein.
Length = 504
Score = 56.8 bits (131), Expect = 5e-08
Identities = 38/137 (27%), Positives = 67/137 (48%), Gaps = 9/137 (6%)
Frame = -3
Query: 572 IQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPVWAF 393
+ ++ LD ++ E LRL +++ R +D+ L + + +RK +A+
Sbjct: 340 LNDLPVLDSIIKESLRLSSASLNI-RTAKEDFTLHLEDGS----YNIRKDDIIALYPQLM 394
Query: 392 HRNPEFFPDPLKFDPERFSEENK--------HNIK-PFAYLPFGVGPRNCIGSRFALCEV 240
H +PE +PDPL F +R+ +EN + +K + Y+PFG G C G FA+ E+
Sbjct: 395 HLDPEIYPDPLTFKYDRYLDENGKTKTTFYCNGLKLKYYYMPFGSGATICPGRLFAIHEI 454
Query: 239 KVMAYQLLQHMEISPCE 189
K +L + E+ E
Sbjct: 455 KQFLILMLSYFELELIE 471
>AF372573-1|AAL69652.1| 495|Homo sapiens cytochrome P450 2F1
protein.
Length = 495
Score = 56.8 bits (131), Expect = 5e-08
Identities = 30/88 (34%), Positives = 44/88 (50%)
Frame = -3
Query: 458 DKAKRDFTLRKGTGVAIPVWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGP 279
D A R F + KGT V + H +P F P +F+PE F + N+ K A++PF G
Sbjct: 378 DTAFRGFLIPKGTDVITLLNTVHYDPSQFLTPQEFNPEHFLDANQSFKKSPAFMPFSAGR 437
Query: 278 RNCIGSRFALCEVKVMAYQLLQHMEISP 195
R C+G A E+ + +LQ + P
Sbjct: 438 RLCLGESLARMELFLYLTAILQSFSLQP 465
>Y07508-1|CAA68807.1| 503|Homo sapiens protein ( Human mRNA for
aromatase P-450. ).
Length = 503
Score = 56.4 bits (130), Expect = 7e-08
Identities = 30/91 (32%), Positives = 48/91 (52%), Gaps = 1/91 (1%)
Frame = -3
Query: 440 FTLRKGTGVAIPVWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYL-PFGVGPRNCIG 264
+ ++KGT + + + HR EFFP P +F E F++ N+ P+ Y PFG GPR C G
Sbjct: 386 YPVKKGTNIILNIGRMHRL-EFFPKPNEFTLENFAK----NV-PYRYFQPFGFGPRGCAG 439
Query: 263 SRFALCEVKVMAYQLLQHMEISPCEKTCIPS 171
A+ +K + LL+ + + C+ S
Sbjct: 440 KYIAMVMMKAILVTLLRRFHVKTLQGQCVES 470
>X13589-1|CAA31929.1| 503|Homo sapiens protein ( Human mRNA for
aromatase (estrogen synthetase). ).
Length = 503
Score = 56.4 bits (130), Expect = 7e-08
Identities = 30/91 (32%), Positives = 48/91 (52%), Gaps = 1/91 (1%)
Frame = -3
Query: 440 FTLRKGTGVAIPVWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYL-PFGVGPRNCIG 264
+ ++KGT + + + HR EFFP P +F E F++ N+ P+ Y PFG GPR C G
Sbjct: 386 YPVKKGTNIILNIGRMHRL-EFFPKPNEFTLENFAK----NV-PYRYFQPFGFGPRGCAG 439
Query: 263 SRFALCEVKVMAYQLLQHMEISPCEKTCIPS 171
A+ +K + LL+ + + C+ S
Sbjct: 440 KYIAMVMMKAILVTLLRRFHVKTLQGQCVES 470
>M30804-1|AAA35728.1| 503|Homo sapiens protein ( Human aromatase
cytochrome P-450 gene, exon 10. ).
Length = 503
Score = 56.4 bits (130), Expect = 7e-08
Identities = 30/91 (32%), Positives = 48/91 (52%), Gaps = 1/91 (1%)
Frame = -3
Query: 440 FTLRKGTGVAIPVWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYL-PFGVGPRNCIG 264
+ ++KGT + + + HR EFFP P +F E F++ N+ P+ Y PFG GPR C G
Sbjct: 386 YPVKKGTNIILNIGRMHRL-EFFPKPNEFTLENFAK----NV-PYRYFQPFGFGPRGCAG 439
Query: 263 SRFALCEVKVMAYQLLQHMEISPCEKTCIPS 171
A+ +K + LL+ + + C+ S
Sbjct: 440 KYIAMVMMKAILVTLLRRFHVKTLQGQCVES 470
>M28420-1|AAA52141.1| 419|Homo sapiens cytochrome P-450 aromatase
protein.
Length = 419
Score = 56.4 bits (130), Expect = 7e-08
Identities = 30/91 (32%), Positives = 48/91 (52%), Gaps = 1/91 (1%)
Frame = -3
Query: 440 FTLRKGTGVAIPVWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYL-PFGVGPRNCIG 264
+ ++KGT + + + HR EFFP P +F E F++ N+ P+ Y PFG GPR C G
Sbjct: 302 YPVKKGTNIILNIGRMHRL-EFFPKPNEFTLENFAK----NV-PYRYFQPFGFGPRGCAG 355
Query: 263 SRFALCEVKVMAYQLLQHMEISPCEKTCIPS 171
A+ +K + LL+ + + C+ S
Sbjct: 356 KYIAMVMMKAILVTLLRRFHVKTLQGQCVES 386
>M22246-1|AAA35557.1| 503|Homo sapiens protein ( Human aromatase
mRNA, complete cds. ).
Length = 503
Score = 56.4 bits (130), Expect = 7e-08
Identities = 30/91 (32%), Positives = 48/91 (52%), Gaps = 1/91 (1%)
Frame = -3
Query: 440 FTLRKGTGVAIPVWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYL-PFGVGPRNCIG 264
+ ++KGT + + + HR EFFP P +F E F++ N+ P+ Y PFG GPR C G
Sbjct: 386 YPVKKGTNIILNIGRMHRL-EFFPKPNEFTLENFAK----NV-PYRYFQPFGFGPRGCAG 439
Query: 263 SRFALCEVKVMAYQLLQHMEISPCEKTCIPS 171
A+ +K + LL+ + + C+ S
Sbjct: 440 KYIAMVMMKAILVTLLRRFHVKTLQGQCVES 470
>M18856-1|AAA35556.1| 419|Homo sapiens protein ( Human aromatase
(Aro1) mRNA, complete cds. ).
Length = 419
Score = 56.4 bits (130), Expect = 7e-08
Identities = 30/91 (32%), Positives = 48/91 (52%), Gaps = 1/91 (1%)
Frame = -3
Query: 440 FTLRKGTGVAIPVWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYL-PFGVGPRNCIG 264
+ ++KGT + + + HR EFFP P +F E F++ N+ P+ Y PFG GPR C G
Sbjct: 302 YPVKKGTNIILNIGRMHRL-EFFPKPNEFTLENFAK----NV-PYRYFQPFGFGPRGCAG 355
Query: 263 SRFALCEVKVMAYQLLQHMEISPCEKTCIPS 171
A+ +K + LL+ + + C+ S
Sbjct: 356 KYIAMVMMKAILVTLLRRFHVKTLQGQCVES 386
>J04127-1|AAA52132.1| 503|Homo sapiens CYP19 protein.
Length = 503
Score = 56.4 bits (130), Expect = 7e-08
Identities = 30/91 (32%), Positives = 48/91 (52%), Gaps = 1/91 (1%)
Frame = -3
Query: 440 FTLRKGTGVAIPVWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYL-PFGVGPRNCIG 264
+ ++KGT + + + HR EFFP P +F E F++ N+ P+ Y PFG GPR C G
Sbjct: 386 YPVKKGTNIILNIGRMHRL-EFFPKPNEFTLENFAK----NV-PYRYFQPFGFGPRGCAG 439
Query: 263 SRFALCEVKVMAYQLLQHMEISPCEKTCIPS 171
A+ +K + LL+ + + C+ S
Sbjct: 440 KYIAMVMMKAILVTLLRRFHVKTLQGQCVES 470
>J02906-1|AAA52156.1| 491|Homo sapiens CYP2F1 protein.
Length = 491
Score = 56.4 bits (130), Expect = 7e-08
Identities = 30/88 (34%), Positives = 44/88 (50%)
Frame = -3
Query: 458 DKAKRDFTLRKGTGVAIPVWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGP 279
D A R F + KGT V + H +P F P +F+PE F + N+ K A++PF G
Sbjct: 374 DTAFRGFLIPKGTDVITLLNTVHYDPSQFLTPQEFNPEHFLDANQSFKKSPAFMPFSAGR 433
Query: 278 RNCIGSRFALCEVKVMAYQLLQHMEISP 195
R C+G A E+ + +LQ + P
Sbjct: 434 RLCLGELLARMELFLYLTAILQSFSLQP 461
>DQ118405-1|AAZ23558.1| 503|Homo sapiens cytochrome P450 subfamily
19 subfamily A polypeptide 1 protein.
Length = 503
Score = 56.4 bits (130), Expect = 7e-08
Identities = 30/91 (32%), Positives = 48/91 (52%), Gaps = 1/91 (1%)
Frame = -3
Query: 440 FTLRKGTGVAIPVWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYL-PFGVGPRNCIG 264
+ ++KGT + + + HR EFFP P +F E F++ N+ P+ Y PFG GPR C G
Sbjct: 386 YPVKKGTNIILNIGRMHRL-EFFPKPNEFTLENFAK----NV-PYRYFQPFGFGPRGCAG 439
Query: 263 SRFALCEVKVMAYQLLQHMEISPCEKTCIPS 171
A+ +K + LL+ + + C+ S
Sbjct: 440 KYIAMVMMKAILVTLLRRFHVKTLQGQCVES 470
>BC107785-1|AAI07786.1| 503|Homo sapiens cytochrome P450, family
19, subfamily A, polypeptide 1 protein.
Length = 503
Score = 56.4 bits (130), Expect = 7e-08
Identities = 30/91 (32%), Positives = 48/91 (52%), Gaps = 1/91 (1%)
Frame = -3
Query: 440 FTLRKGTGVAIPVWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYL-PFGVGPRNCIG 264
+ ++KGT + + + HR EFFP P +F E F++ N+ P+ Y PFG GPR C G
Sbjct: 386 YPVKKGTNIILNIGRMHRL-EFFPKPNEFTLENFAK----NV-PYRYFQPFGFGPRGCAG 439
Query: 263 SRFALCEVKVMAYQLLQHMEISPCEKTCIPS 171
A+ +K + LL+ + + C+ S
Sbjct: 440 KYIAMVMMKAILVTLLRRFHVKTLQGQCVES 470
>BC104909-1|AAI04910.1| 501|Homo sapiens cytochrome P450, family 2,
subfamily R, polypeptide 1 protein.
Length = 501
Score = 56.4 bits (130), Expect = 7e-08
Identities = 27/86 (31%), Positives = 47/86 (54%)
Frame = -3
Query: 458 DKAKRDFTLRKGTGVAIPVWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGP 279
D R +++ KGT V +++ H + +++ DP F PERF + + + K A +PF +G
Sbjct: 386 DAVVRGYSIPKGTTVITNLYSVHFDEKYWRDPEVFHPERFLDSSGYFAKKEALVPFSLGR 445
Query: 278 RNCIGSRFALCEVKVMAYQLLQHMEI 201
R+C+G A E+ + LLQ +
Sbjct: 446 RHCLGEHLARMEMFLFFTALLQRFHL 471
>BC104907-1|AAI04908.1| 501|Homo sapiens cytochrome P450, family 2,
subfamily R, polypeptide 1 protein.
Length = 501
Score = 56.4 bits (130), Expect = 7e-08
Identities = 27/86 (31%), Positives = 47/86 (54%)
Frame = -3
Query: 458 DKAKRDFTLRKGTGVAIPVWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGP 279
D R +++ KGT V +++ H + +++ DP F PERF + + + K A +PF +G
Sbjct: 386 DAVVRGYSIPKGTTVITNLYSVHFDEKYWRDPEVFHPERFLDSSGYFAKKEALVPFSLGR 445
Query: 278 RNCIGSRFALCEVKVMAYQLLQHMEI 201
R+C+G A E+ + LLQ +
Sbjct: 446 RHCLGEHLARMEMFLFFTALLQRFHL 471
>BC035959-1|AAH35959.1| 503|Homo sapiens cytochrome P450, family
19, subfamily A, polypeptide 1 protein.
Length = 503
Score = 56.4 bits (130), Expect = 7e-08
Identities = 30/91 (32%), Positives = 48/91 (52%), Gaps = 1/91 (1%)
Frame = -3
Query: 440 FTLRKGTGVAIPVWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYL-PFGVGPRNCIG 264
+ ++KGT + + + HR EFFP P +F E F++ N+ P+ Y PFG GPR C G
Sbjct: 386 YPVKKGTNIILNIGRMHRL-EFFPKPNEFTLENFAK----NV-PYRYFQPFGFGPRGCAG 439
Query: 263 SRFALCEVKVMAYQLLQHMEISPCEKTCIPS 171
A+ +K + LL+ + + C+ S
Sbjct: 440 KYIAMVMMKAILVTLLRRFHVKTLQGQCVES 470
>AY957953-1|AAX44046.1| 503|Homo sapiens cytochrome P450, family
19, subfamily A, polypeptide 1 protein.
Length = 503
Score = 56.4 bits (130), Expect = 7e-08
Identities = 30/91 (32%), Positives = 48/91 (52%), Gaps = 1/91 (1%)
Frame = -3
Query: 440 FTLRKGTGVAIPVWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYL-PFGVGPRNCIG 264
+ ++KGT + + + HR EFFP P +F E F++ N+ P+ Y PFG GPR C G
Sbjct: 386 YPVKKGTNIILNIGRMHRL-EFFPKPNEFTLENFAK----NV-PYRYFQPFGFGPRGCAG 439
Query: 263 SRFALCEVKVMAYQLLQHMEISPCEKTCIPS 171
A+ +K + LL+ + + C+ S
Sbjct: 440 KYIAMVMMKAILVTLLRRFHVKTLQGQCVES 470
>AY323817-1|AAQ23114.1| 501|Homo sapiens cytochrome P450 2R1
protein.
Length = 501
Score = 56.4 bits (130), Expect = 7e-08
Identities = 27/86 (31%), Positives = 47/86 (54%)
Frame = -3
Query: 458 DKAKRDFTLRKGTGVAIPVWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGP 279
D R +++ KGT V +++ H + +++ DP F PERF + + + K A +PF +G
Sbjct: 386 DAVVRGYSIPKGTTVITNLYSVHFDEKYWRDPEVFHPERFLDSSGYFAKKEALVPFSLGR 445
Query: 278 RNCIGSRFALCEVKVMAYQLLQHMEI 201
R+C+G A E+ + LLQ +
Sbjct: 446 RHCLGEHLARMEMFLFFTALLQRFHL 471
>AL358613-1|CAH72802.2| 522|Homo sapiens cytochrome P450, family
26, subfamily C, polypeptide 1 protein.
Length = 522
Score = 56.0 bits (129), Expect = 9e-08
Identities = 36/119 (30%), Positives = 59/119 (49%), Gaps = 4/119 (3%)
Frame = -3
Query: 557 YLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPVWAFHRNPE 378
Y+D VV E+LRL PP R ++ + L + + KG V + H
Sbjct: 368 YVDCVVKEVLRLLPPVSGGYRTALRTFELD--------GYQIPKGWSVMYSIRDTHETAA 419
Query: 377 FFPDPLK-FDPERFS---EENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQLLQ 213
+ P + FDPERF E+++ F Y+PFG G R+C+G A ++++A +L++
Sbjct: 420 VYRSPPEGFDPERFGAAREDSRGASSRFHYIPFGGGARSCLGQELAQAVLQLLAVELVR 478
>X56088-1|CAA39568.1| 504|Homo sapiens cholesterol
7-alpha-hydroxylase protein.
Length = 504
Score = 55.6 bits (128), Expect = 1e-07
Identities = 37/137 (27%), Positives = 68/137 (49%), Gaps = 9/137 (6%)
Frame = -3
Query: 572 IQNMVYLDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPVWAF 393
+ ++ L+ ++ E LRL +++ R +D+ L + + +RK + +A+
Sbjct: 340 LNDLPVLNSIIKESLRLSSASLNI-RTAKEDFTLHLEDGS----YNIRKDSIIALYPQLM 394
Query: 392 HRNPEFFPDPLKFDPERFSEENK--------HNIK-PFAYLPFGVGPRNCIGSRFALCEV 240
H +PE +PDPL F +R+ +EN + +K + Y+PFG G C G FA+ E+
Sbjct: 395 HLDPEIYPDPLTFKYDRYLDENGKTKTTFYCNGLKLKYYYMPFGSGATICPGRLFAIHEI 454
Query: 239 KVMAYQLLQHMEISPCE 189
K +L + E+ E
Sbjct: 455 KQFLILMLSYFELELIE 471
>X08006-1|CAA30807.1| 497|Homo sapiens cytochrome P450 db1 protein.
Length = 497
Score = 55.6 bits (128), Expect = 1e-07
Identities = 27/81 (33%), Positives = 41/81 (50%)
Frame = -3
Query: 440 FTLRKGTGVAIPVWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGS 261
F + KGT + + + ++ + P +F PE F + H +KP A+LPF G R C+G
Sbjct: 387 FRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGE 446
Query: 260 RFALCEVKVMAYQLLQHMEIS 198
A E+ + LLQH S
Sbjct: 447 PLARMELFLFFTSLLQHFSFS 467
>M33388-1|AAA53500.1| 497|Homo sapiens cytochrome P450 IID6
protein.
Length = 497
Score = 55.6 bits (128), Expect = 1e-07
Identities = 27/81 (33%), Positives = 41/81 (50%)
Frame = -3
Query: 440 FTLRKGTGVAIPVWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGS 261
F + KGT + + + ++ + P +F PE F + H +KP A+LPF G R C+G
Sbjct: 387 FRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGE 446
Query: 260 RFALCEVKVMAYQLLQHMEIS 198
A E+ + LLQH S
Sbjct: 447 PLARMELFLFFTSLLQHFSFS 467
>M33189-1|AAA35737.1| 500|Homo sapiens protein ( Human debrisoquine
4-hydroxylase mutant allele (CYP2D6-MA1) gene, complete
cds. ).
Length = 500
Score = 55.6 bits (128), Expect = 1e-07
Identities = 27/81 (33%), Positives = 41/81 (50%)
Frame = -3
Query: 440 FTLRKGTGVAIPVWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGS 261
F + KGT + + + ++ + P +F PE F + H +KP A+LPF G R C+G
Sbjct: 390 FRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGE 449
Query: 260 RFALCEVKVMAYQLLQHMEIS 198
A E+ + LLQH S
Sbjct: 450 PLARMELFLFFTSLLQHFSFS 470
>M24499-1|AAA36403.1| 373|Homo sapiens cytochrome P450db1 protein.
Length = 373
Score = 55.6 bits (128), Expect = 1e-07
Identities = 27/81 (33%), Positives = 41/81 (50%)
Frame = -3
Query: 440 FTLRKGTGVAIPVWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGS 261
F + KGT + + + ++ + P +F PE F + H +KP A+LPF G R C+G
Sbjct: 263 FRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGE 322
Query: 260 RFALCEVKVMAYQLLQHMEIS 198
A E+ + LLQH S
Sbjct: 323 PLARMELFLFFTSLLQHFSFS 343
>M20403-1|AAA52153.1| 497|Homo sapiens CYP2D protein.
Length = 497
Score = 55.6 bits (128), Expect = 1e-07
Identities = 27/81 (33%), Positives = 41/81 (50%)
Frame = -3
Query: 440 FTLRKGTGVAIPVWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGS 261
F + KGT + + + ++ + P +F PE F + H +KP A+LPF G R C+G
Sbjct: 387 FRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGE 446
Query: 260 RFALCEVKVMAYQLLQHMEIS 198
A E+ + LLQH S
Sbjct: 447 PLARMELFLFFTSLLQHFSFS 467
>DQ282162-1|ABB77909.1| 500|Homo sapiens cytochrome P450 2D6
protein.
Length = 500
Score = 55.6 bits (128), Expect = 1e-07
Identities = 27/81 (33%), Positives = 41/81 (50%)
Frame = -3
Query: 440 FTLRKGTGVAIPVWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGS 261
F + KGT + + + ++ + P +F PE F + H +KP A+LPF G R C+G
Sbjct: 390 FRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGE 449
Query: 260 RFALCEVKVMAYQLLQHMEIS 198
A E+ + LLQH S
Sbjct: 450 PLARMELFLFFTSLLQHFSFS 470
>DQ282160-1|ABB77908.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 55.6 bits (128), Expect = 1e-07
Identities = 27/81 (33%), Positives = 41/81 (50%)
Frame = -3
Query: 440 FTLRKGTGVAIPVWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGS 261
F + KGT + + + ++ + P +F PE F + H +KP A+LPF G R C+G
Sbjct: 387 FRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGE 446
Query: 260 RFALCEVKVMAYQLLQHMEIS 198
A E+ + LLQH S
Sbjct: 447 PLARMELFLFFTSLLQHFSFS 467
>DQ282159-1|ABB77907.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 55.6 bits (128), Expect = 1e-07
Identities = 27/81 (33%), Positives = 41/81 (50%)
Frame = -3
Query: 440 FTLRKGTGVAIPVWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGS 261
F + KGT + + + ++ + P +F PE F + H +KP A+LPF G R C+G
Sbjct: 387 FRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGE 446
Query: 260 RFALCEVKVMAYQLLQHMEIS 198
A E+ + LLQH S
Sbjct: 447 PLARMELFLFFTSLLQHFSFS 467
>DQ282158-1|ABB77906.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 55.6 bits (128), Expect = 1e-07
Identities = 27/81 (33%), Positives = 41/81 (50%)
Frame = -3
Query: 440 FTLRKGTGVAIPVWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGS 261
F + KGT + + + ++ + P +F PE F + H +KP A+LPF G R C+G
Sbjct: 387 FRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGE 446
Query: 260 RFALCEVKVMAYQLLQHMEIS 198
A E+ + LLQH S
Sbjct: 447 PLARMELFLFFTSLLQHFSFS 467
>DQ282157-1|ABB77905.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 55.6 bits (128), Expect = 1e-07
Identities = 27/81 (33%), Positives = 41/81 (50%)
Frame = -3
Query: 440 FTLRKGTGVAIPVWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGS 261
F + KGT + + + ++ + P +F PE F + H +KP A+LPF G R C+G
Sbjct: 387 FRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGE 446
Query: 260 RFALCEVKVMAYQLLQHMEIS 198
A E+ + LLQH S
Sbjct: 447 PLARMELFLFFTSLLQHFSFS 467
>DQ282156-1|ABB77904.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 55.6 bits (128), Expect = 1e-07
Identities = 27/81 (33%), Positives = 41/81 (50%)
Frame = -3
Query: 440 FTLRKGTGVAIPVWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGS 261
F + KGT + + + ++ + P +F PE F + H +KP A+LPF G R C+G
Sbjct: 387 FRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGE 446
Query: 260 RFALCEVKVMAYQLLQHMEIS 198
A E+ + LLQH S
Sbjct: 447 PLARMELFLFFTSLLQHFSFS 467
>DQ282155-1|ABB77903.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 55.6 bits (128), Expect = 1e-07
Identities = 27/81 (33%), Positives = 41/81 (50%)
Frame = -3
Query: 440 FTLRKGTGVAIPVWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGS 261
F + KGT + + + ++ + P +F PE F + H +KP A+LPF G R C+G
Sbjct: 387 FRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGE 446
Query: 260 RFALCEVKVMAYQLLQHMEIS 198
A E+ + LLQH S
Sbjct: 447 PLARMELFLFFTSLLQHFSFS 467
>DQ282154-1|ABB77902.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 55.6 bits (128), Expect = 1e-07
Identities = 27/81 (33%), Positives = 41/81 (50%)
Frame = -3
Query: 440 FTLRKGTGVAIPVWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGS 261
F + KGT + + + ++ + P +F PE F + H +KP A+LPF G R C+G
Sbjct: 387 FRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGE 446
Query: 260 RFALCEVKVMAYQLLQHMEIS 198
A E+ + LLQH S
Sbjct: 447 PLARMELFLFFTSLLQHFSFS 467
>DQ282153-1|ABB77901.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 55.6 bits (128), Expect = 1e-07
Identities = 27/81 (33%), Positives = 41/81 (50%)
Frame = -3
Query: 440 FTLRKGTGVAIPVWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGS 261
F + KGT + + + ++ + P +F PE F + H +KP A+LPF G R C+G
Sbjct: 387 FRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGE 446
Query: 260 RFALCEVKVMAYQLLQHMEIS 198
A E+ + LLQH S
Sbjct: 447 PLARMELFLFFTSLLQHFSFS 467
>DQ282152-1|ABB77900.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 55.6 bits (128), Expect = 1e-07
Identities = 27/81 (33%), Positives = 41/81 (50%)
Frame = -3
Query: 440 FTLRKGTGVAIPVWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGS 261
F + KGT + + + ++ + P +F PE F + H +KP A+LPF G R C+G
Sbjct: 387 FRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGE 446
Query: 260 RFALCEVKVMAYQLLQHMEIS 198
A E+ + LLQH S
Sbjct: 447 PLARMELFLFFTSLLQHFSFS 467
>DQ282151-1|ABB77899.1| 496|Homo sapiens cytochrome P450 2D6
protein.
Length = 496
Score = 55.6 bits (128), Expect = 1e-07
Identities = 27/81 (33%), Positives = 41/81 (50%)
Frame = -3
Query: 440 FTLRKGTGVAIPVWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGS 261
F + KGT + + + ++ + P +F PE F + H +KP A+LPF G R C+G
Sbjct: 386 FRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGE 445
Query: 260 RFALCEVKVMAYQLLQHMEIS 198
A E+ + LLQH S
Sbjct: 446 PLARMELFLFFTSLLQHFSFS 466
>DQ282147-1|ABB77898.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 55.6 bits (128), Expect = 1e-07
Identities = 27/81 (33%), Positives = 41/81 (50%)
Frame = -3
Query: 440 FTLRKGTGVAIPVWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGS 261
F + KGT + + + ++ + P +F PE F + H +KP A+LPF G R C+G
Sbjct: 387 FRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGE 446
Query: 260 RFALCEVKVMAYQLLQHMEIS 198
A E+ + LLQH S
Sbjct: 447 PLARMELFLFFTSLLQHFSFS 467
>DQ282146-1|ABB77897.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 55.6 bits (128), Expect = 1e-07
Identities = 27/81 (33%), Positives = 41/81 (50%)
Frame = -3
Query: 440 FTLRKGTGVAIPVWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGS 261
F + KGT + + + ++ + P +F PE F + H +KP A+LPF G R C+G
Sbjct: 387 FRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGE 446
Query: 260 RFALCEVKVMAYQLLQHMEIS 198
A E+ + LLQH S
Sbjct: 447 PLARMELFLFFTSLLQHFSFS 467
>DQ282145-1|ABB77896.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 55.6 bits (128), Expect = 1e-07
Identities = 27/81 (33%), Positives = 41/81 (50%)
Frame = -3
Query: 440 FTLRKGTGVAIPVWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGS 261
F + KGT + + + ++ + P +F PE F + H +KP A+LPF G R C+G
Sbjct: 387 FRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGE 446
Query: 260 RFALCEVKVMAYQLLQHMEIS 198
A E+ + LLQH S
Sbjct: 447 PLARMELFLFFTSLLQHFSFS 467
>DQ282144-1|ABB77895.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 55.6 bits (128), Expect = 1e-07
Identities = 27/81 (33%), Positives = 41/81 (50%)
Frame = -3
Query: 440 FTLRKGTGVAIPVWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGS 261
F + KGT + + + ++ + P +F PE F + H +KP A+LPF G R C+G
Sbjct: 387 FRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGE 446
Query: 260 RFALCEVKVMAYQLLQHMEIS 198
A E+ + LLQH S
Sbjct: 447 PLARMELFLFFTSLLQHFSFS 467
>DQ211354-2|ABB01372.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 55.6 bits (128), Expect = 1e-07
Identities = 27/81 (33%), Positives = 41/81 (50%)
Frame = -3
Query: 440 FTLRKGTGVAIPVWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGS 261
F + KGT + + + ++ + P +F PE F + H +KP A+LPF G R C+G
Sbjct: 387 FRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGE 446
Query: 260 RFALCEVKVMAYQLLQHMEIS 198
A E+ + LLQH S
Sbjct: 447 PLARMELFLFFTSLLQHFSFS 467
>DQ211353-2|ABB01371.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 55.6 bits (128), Expect = 1e-07
Identities = 27/81 (33%), Positives = 41/81 (50%)
Frame = -3
Query: 440 FTLRKGTGVAIPVWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGS 261
F + KGT + + + ++ + P +F PE F + H +KP A+LPF G R C+G
Sbjct: 387 FRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGE 446
Query: 260 RFALCEVKVMAYQLLQHMEIS 198
A E+ + LLQH S
Sbjct: 447 PLARMELFLFFTSLLQHFSFS 467
>DQ211353-1|ABB01370.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 55.6 bits (128), Expect = 1e-07
Identities = 27/81 (33%), Positives = 41/81 (50%)
Frame = -3
Query: 440 FTLRKGTGVAIPVWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGS 261
F + KGT + + + ++ + P +F PE F + H +KP A+LPF G R C+G
Sbjct: 387 FRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGE 446
Query: 260 RFALCEVKVMAYQLLQHMEIS 198
A E+ + LLQH S
Sbjct: 447 PLARMELFLFFTSLLQHFSFS 467
>CR456430-1|CAG30316.1| 446|Homo sapiens CYP2D6 protein.
Length = 446
Score = 55.6 bits (128), Expect = 1e-07
Identities = 27/81 (33%), Positives = 41/81 (50%)
Frame = -3
Query: 440 FTLRKGTGVAIPVWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGS 261
F + KGT + + + ++ + P +F PE F + H +KP A+LPF G R C+G
Sbjct: 336 FRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGE 395
Query: 260 RFALCEVKVMAYQLLQHMEIS 198
A E+ + LLQH S
Sbjct: 396 PLARMELFLFFTSLLQHFSFS 416
>BC126858-1|AAI26859.1| 497|Homo sapiens cytochrome P450, family 2,
subfamily D, polypeptide 6 protein.
Length = 497
Score = 55.6 bits (128), Expect = 1e-07
Identities = 27/81 (33%), Positives = 41/81 (50%)
Frame = -3
Query: 440 FTLRKGTGVAIPVWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGS 261
F + KGT + + + ++ + P +F PE F + H +KP A+LPF G R C+G
Sbjct: 387 FRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGE 446
Query: 260 RFALCEVKVMAYQLLQHMEIS 198
A E+ + LLQH S
Sbjct: 447 PLARMELFLFFTSLLQHFSFS 467
>BC106758-1|AAI06759.1| 497|Homo sapiens cytochrome P450, family 2,
subfamily D, polypeptide 6 protein.
Length = 497
Score = 55.6 bits (128), Expect = 1e-07
Identities = 27/81 (33%), Positives = 41/81 (50%)
Frame = -3
Query: 440 FTLRKGTGVAIPVWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGS 261
F + KGT + + + ++ + P +F PE F + H +KP A+LPF G R C+G
Sbjct: 387 FRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGE 446
Query: 260 RFALCEVKVMAYQLLQHMEIS 198
A E+ + LLQH S
Sbjct: 447 PLARMELFLFFTSLLQHFSFS 467
>BC106757-1|AAI06758.1| 446|Homo sapiens cytochrome P450, family 2,
subfamily D, polypeptide 6 protein.
Length = 446
Score = 55.6 bits (128), Expect = 1e-07
Identities = 27/81 (33%), Positives = 41/81 (50%)
Frame = -3
Query: 440 FTLRKGTGVAIPVWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGS 261
F + KGT + + + ++ + P +F PE F + H +KP A+LPF G R C+G
Sbjct: 336 FRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGE 395
Query: 260 RFALCEVKVMAYQLLQHMEIS 198
A E+ + LLQH S
Sbjct: 396 PLARMELFLFFTSLLQHFSFS 416
>BC075024-1|AAH75024.1| 497|Homo sapiens cytochrome P450, family 2,
subfamily D, polypeptide 6 protein.
Length = 497
Score = 55.6 bits (128), Expect = 1e-07
Identities = 27/81 (33%), Positives = 41/81 (50%)
Frame = -3
Query: 440 FTLRKGTGVAIPVWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGS 261
F + KGT + + + ++ + P +F PE F + H +KP A+LPF G R C+G
Sbjct: 387 FRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGE 446
Query: 260 RFALCEVKVMAYQLLQHMEIS 198
A E+ + LLQH S
Sbjct: 447 PLARMELFLFFTSLLQHFSFS 467
>BC075023-1|AAH75023.1| 497|Homo sapiens cytochrome P450, family 2,
subfamily D, polypeptide 6 protein.
Length = 497
Score = 55.6 bits (128), Expect = 1e-07
Identities = 27/81 (33%), Positives = 41/81 (50%)
Frame = -3
Query: 440 FTLRKGTGVAIPVWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGS 261
F + KGT + + + ++ + P +F PE F + H +KP A+LPF G R C+G
Sbjct: 387 FRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGE 446
Query: 260 RFALCEVKVMAYQLLQHMEIS 198
A E+ + LLQH S
Sbjct: 447 PLARMELFLFFTSLLQHFSFS 467
>BC067432-1|AAH67432.1| 497|Homo sapiens cytochrome P450, family 2,
subfamily D, polypeptide 6 protein.
Length = 497
Score = 55.6 bits (128), Expect = 1e-07
Identities = 27/81 (33%), Positives = 41/81 (50%)
Frame = -3
Query: 440 FTLRKGTGVAIPVWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGS 261
F + KGT + + + ++ + P +F PE F + H +KP A+LPF G R C+G
Sbjct: 387 FRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGE 446
Query: 260 RFALCEVKVMAYQLLQHMEIS 198
A E+ + LLQH S
Sbjct: 447 PLARMELFLFFTSLLQHFSFS 467
>BC066877-1|AAH66877.1| 446|Homo sapiens CYP2D6 protein protein.
Length = 446
Score = 55.6 bits (128), Expect = 1e-07
Identities = 27/81 (33%), Positives = 41/81 (50%)
Frame = -3
Query: 440 FTLRKGTGVAIPVWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGS 261
F + KGT + + + ++ + P +F PE F + H +KP A+LPF G R C+G
Sbjct: 336 FRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGE 395
Query: 260 RFALCEVKVMAYQLLQHMEIS 198
A E+ + LLQH S
Sbjct: 396 PLARMELFLFFTSLLQHFSFS 416
>AY545216-1|AAS55001.1| 497|Homo sapiens cytochrome P4502D6
protein.
Length = 497
Score = 55.6 bits (128), Expect = 1e-07
Identities = 27/81 (33%), Positives = 41/81 (50%)
Frame = -3
Query: 440 FTLRKGTGVAIPVWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGS 261
F + KGT + + + ++ + P +F PE F + H +KP A+LPF G R C+G
Sbjct: 387 FRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGE 446
Query: 260 RFALCEVKVMAYQLLQHMEIS 198
A E+ + LLQH S
Sbjct: 447 PLARMELFLFFTSLLQHFSFS 467
>AY220845-1|AAO49806.1| 516|Homo sapiens cytochrome P450 protein.
Length = 516
Score = 55.6 bits (128), Expect = 1e-07
Identities = 27/81 (33%), Positives = 41/81 (50%)
Frame = -3
Query: 440 FTLRKGTGVAIPVWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGS 261
F + KGT + + + ++ + P +F PE F + H +KP A+LPF G R C+G
Sbjct: 406 FRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGE 465
Query: 260 RFALCEVKVMAYQLLQHMEIS 198
A E+ + LLQH S
Sbjct: 466 PLARMELFLFFTSLLQHFSFS 486
>AB209492-1|BAD92729.1| 566|Homo sapiens Debrisoquine 4-hydroxylase
mutant allele variant protein.
Length = 566
Score = 55.6 bits (128), Expect = 1e-07
Identities = 27/81 (33%), Positives = 41/81 (50%)
Frame = -3
Query: 440 FTLRKGTGVAIPVWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGS 261
F + KGT + + + ++ + P +F PE F + H +KP A+LPF G R C+G
Sbjct: 456 FRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGE 515
Query: 260 RFALCEVKVMAYQLLQHMEIS 198
A E+ + LLQH S
Sbjct: 516 PLARMELFLFFTSLLQHFSFS 536
>M33317-1|AAA52138.1| 494|Homo sapiens CYP2A protein.
Length = 494
Score = 55.2 bits (127), Expect = 2e-07
Identities = 28/86 (32%), Positives = 45/86 (52%)
Frame = -3
Query: 458 DKAKRDFTLRKGTGVAIPVWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGP 279
D RDF L KGT V + + R+P FF +P F+P+ F ++ K A++PF +G
Sbjct: 377 DTKFRDFFLPKGTEVFPMLGSVLRDPSFFSNPQDFNPQHFLDDKGQFKKSDAFVPFSIGK 436
Query: 278 RNCIGSRFALCEVKVMAYQLLQHMEI 201
R C G A E+ + ++Q+ +
Sbjct: 437 RYCFGEGLARMELFLFFTTVMQNFRL 462
>BC117165-1|AAI17166.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 7 protein.
Length = 494
Score = 55.2 bits (127), Expect = 2e-07
Identities = 28/86 (32%), Positives = 45/86 (52%)
Frame = -3
Query: 458 DKAKRDFTLRKGTGVAIPVWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGP 279
D RDF L KGT V + + R+P FF +P F+P+ F ++ K A++PF +G
Sbjct: 377 DTKFRDFFLPKGTEVFPMLGSVLRDPSFFSNPQDFNPQHFLDDKGQFKKSDAFVPFSIGK 436
Query: 278 RNCIGSRFALCEVKVMAYQLLQHMEI 201
R C G A E+ + ++Q+ +
Sbjct: 437 RYCFGEGLARMELFLFFTTVMQNFRL 462
>M32881-1|AAA35741.1| 503|Homo sapiens protein ( Human steroid
11-beta-hydroxylase-like-enzyme (CYP11B2) gene, exon 9.
).
Length = 503
Score = 54.8 bits (126), Expect = 2e-07
Identities = 31/114 (27%), Positives = 61/114 (53%)
Frame = -3
Query: 554 LDMVVSELLRLWPPGVSMDRICVQDYNLGKPNDKAKRDFTLRKGTGVAIPVWAFHRNPEF 375
L + E LRL+P G+ ++R+ D L +++ + GT V + +++ RN
Sbjct: 365 LRAALKETLRLYPVGLFLERVVSSDLVL--------QNYHIPAGTLVQVFLYSLGRNAAL 416
Query: 374 FPDPLKFDPERFSEENKHNIKPFAYLPFGVGPRNCIGSRFALCEVKVMAYQLLQ 213
FP P +++P+R+ + + ++PFG G R C+G R A E+ ++ + +L+
Sbjct: 417 FPRPERYNPQRWLDIRGSG-RNLHHVPFGFGMRQCLGRRLAEAEMLLLLHHVLK 469
>AY513609-1|AAR90940.1| 494|Homo sapiens cytochrome P450 2A13
variant 6 protein.
Length = 494
Score = 54.4 bits (125), Expect = 3e-07
Identities = 28/83 (33%), Positives = 44/83 (53%)
Frame = -3
Query: 458 DKAKRDFTLRKGTGVAIPVWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGP 279
D RDF L KGT V + + R+P FF +P F+P+ F ++ K A++PF +G
Sbjct: 377 DTKFRDFFLPKGTEVFPMLGSVLRDPRFFSNPRDFNPQHFLDKKGQFKKSDAFVPFSIGK 436
Query: 278 RNCIGSRFALCEVKVMAYQLLQH 210
R C G A E+ + ++Q+
Sbjct: 437 RYCFGEGLARMELFLFFTTIMQN 459
>AY513608-1|AAR90939.1| 494|Homo sapiens cytochrome P450 2A13
variant 5 protein.
Length = 494
Score = 54.4 bits (125), Expect = 3e-07
Identities = 28/83 (33%), Positives = 44/83 (53%)
Frame = -3
Query: 458 DKAKRDFTLRKGTGVAIPVWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGP 279
D RDF L KGT V + + R+P FF +P F+P+ F ++ K A++PF +G
Sbjct: 377 DTKFRDFFLPKGTEVFPMLGSVLRDPRFFSNPRDFNPQHFLDKKGQFKKSDAFVPFSIGK 436
Query: 278 RNCIGSRFALCEVKVMAYQLLQH 210
R C G A E+ + ++Q+
Sbjct: 437 RYCFGEGLARMELFLFFTTIMQN 459
>AY513606-1|AAR90937.1| 494|Homo sapiens cytochrome P450 2A13
variant 3 protein.
Length = 494
Score = 54.4 bits (125), Expect = 3e-07
Identities = 28/83 (33%), Positives = 44/83 (53%)
Frame = -3
Query: 458 DKAKRDFTLRKGTGVAIPVWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGP 279
D RDF L KGT V + + R+P FF +P F+P+ F ++ K A++PF +G
Sbjct: 377 DTKFRDFFLPKGTEVFPMLGSVLRDPRFFSNPRDFNPQHFLDKKGQFKKSDAFVPFSIGK 436
Query: 278 RNCIGSRFALCEVKVMAYQLLQH 210
R C G A E+ + ++Q+
Sbjct: 437 RYCFGEGLARMELFLFFTTIMQN 459
>AY513605-1|AAR90936.1| 494|Homo sapiens cytochrome P450 2A13
variant 2 protein.
Length = 494
Score = 54.4 bits (125), Expect = 3e-07
Identities = 28/83 (33%), Positives = 44/83 (53%)
Frame = -3
Query: 458 DKAKRDFTLRKGTGVAIPVWAFHRNPEFFPDPLKFDPERFSEENKHNIKPFAYLPFGVGP 279
D RDF L KGT V + + R+P FF +P F+P+ F ++ K A++PF +G
Sbjct: 377 DTKFRDFFLPKGTEVFPMLGSVLRDPRFFSNPRDFNPQHFLDKKGQFKKSDAFVPFSIGK 436
Query: 278 RNCIGSRFALCEVKVMAYQLLQH 210
R C G A E+ + ++Q+
Sbjct: 437 RYCFGEGLARMELFLFFTTIMQN 459
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 90,780,568
Number of Sequences: 237096
Number of extensions: 2084610
Number of successful extensions: 4234
Number of sequences better than 10.0: 444
Number of HSP's better than 10.0 without gapping: 3792
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3918
length of database: 76,859,062
effective HSP length: 86
effective length of database: 56,468,806
effective search space used: 6155099854
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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