Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P11_F_K04
(822 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC024202-1|AAH24202.1| 521|Homo sapiens karyopherin alpha 3 (im... 388 e-107
BC017355-1|AAH17355.1| 521|Homo sapiens karyopherin alpha 3 (im... 388 e-107
AL136301-1|CAH71145.1| 521|Homo sapiens karyopherin alpha 3 (im... 388 e-107
AL135901-3|CAI40716.1| 521|Homo sapiens karyopherin alpha 3 (im... 388 e-107
AK223480-1|BAD97200.1| 521|Homo sapiens karyopherin alpha 3 var... 388 e-107
AF005263-1|AAQ13404.1| 521|Homo sapiens importin alpha-3 subuni... 388 e-107
D89618-1|BAA20378.1| 521|Homo sapiens karyopherin alhph 3 protein. 387 e-107
BC035090-1|AAH35090.1| 521|Homo sapiens karyopherin alpha 3 (im... 387 e-107
Y12394-1|CAA73026.1| 521|Homo sapiens SRP1-like protein protein. 386 e-107
AF034756-1|AAB87693.1| 521|Homo sapiens importin-alpha homolog ... 382 e-105
U93240-1|AAC25605.1| 521|Homo sapiens importin alpha 3 protein. 373 e-103
BC034493-1|AAH34493.1| 521|Homo sapiens karyopherin alpha 4 (im... 373 e-103
BC028691-1|AAH28691.1| 521|Homo sapiens karyopherin alpha 4 (im... 373 e-103
AB002533-1|BAA19546.1| 521|Homo sapiens Qip1 protein. 373 e-103
U28386-1|AAA69957.1| 529|Homo sapiens hSRP1alpha protein. 283 5e-76
U09559-1|AAA65700.1| 529|Homo sapiens Rch1 protein. 283 5e-76
BC053343-1|AAH53343.1| 529|Homo sapiens karyopherin alpha 2 (RA... 283 5e-76
AJ303086-1|CAC83080.1| 529|Homo sapiens karyopherin alpha 2 pro... 283 5e-76
BT006665-1|AAP35311.1| 529|Homo sapiens karyopherin alpha 2 (RA... 283 7e-76
BC005978-1|AAH05978.1| 529|Homo sapiens karyopherin alpha 2 (RA... 283 7e-76
BC067848-1|AAH67848.1| 529|Homo sapiens karyopherin alpha 2 (RA... 277 4e-74
CR456743-1|CAG33024.1| 538|Homo sapiens KPNA1 protein. 237 3e-62
BT006959-1|AAP35605.1| 538|Homo sapiens karyopherin alpha 1 (im... 237 3e-62
BC090864-1|AAH90864.1| 538|Homo sapiens karyopherin alpha 1 (im... 237 3e-62
BC003009-1|AAH03009.1| 538|Homo sapiens karyopherin alpha 1 (im... 237 3e-62
BC002374-1|AAH02374.1| 538|Homo sapiens karyopherin alpha 1 (im... 237 3e-62
BT009843-1|AAP88845.1| 536|Homo sapiens karyopherin alpha 6 (im... 236 8e-62
BC020520-1|AAH20520.1| 536|Homo sapiens karyopherin alpha 6 (im... 236 8e-62
AL445248-5|CAH71948.1| 536|Homo sapiens karyopherin alpha 6 (im... 236 8e-62
AL049795-3|CAI22056.1| 536|Homo sapiens karyopherin alpha 6 (im... 236 8e-62
AF060543-1|AAC15233.1| 536|Homo sapiens importin alpha 7 subuni... 236 8e-62
S75295-1|AAC60648.1| 538|Homo sapiens nucleoprotein interactor ... 234 2e-61
AF005361-1|AAC51868.1| 536|Homo sapiens importin alpha 6 protein. 229 1e-59
BC047409-1|AAH47409.1| 539|Homo sapiens karyopherin alpha 5 (im... 228 2e-59
AL132795-5|CAI20500.1| 539|Homo sapiens karyopherin alpha 5 (im... 228 2e-59
AL049795-1|CAI22054.1| 321|Homo sapiens karyopherin alpha 6 (im... 115 2e-25
AL132795-6|CAI20501.1| 142|Homo sapiens karyopherin alpha 5 (im... 77 1e-13
Y12393-1|CAA73025.1| 281|Homo sapiens SRP1-like protein protein. 60 1e-08
BC030585-1|AAH30585.1| 458|Homo sapiens sperm associated antige... 52 2e-06
CR533552-1|CAG38583.1| 509|Homo sapiens SPAG6 protein. 50 8e-06
AL513128-4|CAH72210.1| 509|Homo sapiens sperm associated antige... 50 8e-06
AL513128-3|CAH72209.1| 458|Homo sapiens sperm associated antige... 50 8e-06
AL158211-15|CAI15963.1| 509|Homo sapiens sperm associated antig... 50 8e-06
AL158211-14|CAI15962.1| 458|Homo sapiens sperm associated antig... 50 8e-06
AF079363-1|AAC32590.1| 509|Homo sapiens sperm flagellar protein... 50 8e-06
AY217348-1|AAO45101.1| 725|Homo sapiens FLJ00019-like protein p... 42 0.004
AK024430-1|BAB15720.1| 732|Homo sapiens FLJ00019 protein protein. 41 0.005
X63465-1|CAA45067.1| 558|Homo sapiens smg GDS protein. 37 0.077
BC099845-1|AAH99845.1| 559|Homo sapiens RAP1GDS1 protein protein. 37 0.077
BC099708-1|AAH99708.1| 558|Homo sapiens RAP1GDS1 protein protein. 37 0.077
BC098334-1|AAH98334.1| 558|Homo sapiens RAP1GDS1 protein protein. 37 0.077
BC041699-1|AAH41699.1| 659|Homo sapiens armadillo repeat contai... 37 0.077
BC032661-1|AAH32661.1| 659|Homo sapiens armadillo repeat contai... 37 0.077
AL096748-1|CAB46423.1| 242|Homo sapiens hypothetical protein pr... 37 0.077
BC014945-1|AAH14945.1| 771|Homo sapiens ARMC5 protein protein. 36 0.18
AL513128-1|CAH72207.1| 246|Homo sapiens sperm associated antige... 36 0.18
AL158211-12|CAI15960.1| 246|Homo sapiens sperm associated antig... 36 0.18
AK023125-1|BAB14418.1| 502|Homo sapiens protein ( Homo sapiens ... 36 0.18
AK001882-1|BAA91959.1| 431|Homo sapiens protein ( Homo sapiens ... 35 0.31
BC011728-1|AAH11728.1| 198|Homo sapiens armadillo repeat contai... 33 0.94
AL513128-2|CAH72208.1| 191|Homo sapiens sperm associated antige... 33 0.94
AL158211-13|CAI15961.1| 191|Homo sapiens sperm associated antig... 33 0.94
AK025813-1|BAB15242.1| 198|Homo sapiens protein ( Homo sapiens ... 33 0.94
BC039312-1|AAH39312.1| 872|Homo sapiens armadillo repeat contai... 33 1.2
AY436643-1|AAR99738.1| 688|Homo sapiens beta-catenin-like prote... 33 1.2
AL139815-2|CAH72189.1| 875|Homo sapiens novel protein protein. 33 1.2
AL139815-1|CAH72188.1| 546|Homo sapiens novel protein protein. 33 1.2
AK057389-1|BAB71463.1| 669|Homo sapiens protein ( Homo sapiens ... 33 1.2
D50550-1|BAA19516.1| 1032|Homo sapiens LLGL protein. 33 1.6
Z83131-1|CAI42019.1| 632|Homo sapiens armadillo repeat containi... 32 2.9
BC015926-1|AAH15926.1| 632|Homo sapiens ARMCX2 protein protein. 32 2.9
BC012541-1|AAH12541.1| 632|Homo sapiens armadillo repeat contai... 32 2.9
AB011084-1|BAA25438.2| 710|Homo sapiens KIAA0512 protein protein. 32 2.9
BC132827-1|AAI32828.1| 949|Homo sapiens CCDC66 protein protein. 31 3.8
BC047509-1|AAH47509.1| 831|Homo sapiens coiled-coil domain cont... 31 3.8
BC009618-1|AAH09618.1| 253|Homo sapiens TMCO6 protein protein. 31 3.8
BC001910-1|AAH01910.1| 253|Homo sapiens TMCO6 protein protein. 31 3.8
AY376900-1|AAQ85126.1| 516|Homo sapiens GTP-GDP dissociation st... 31 5.0
AL390866-5|CAI12711.1| 1044|Homo sapiens novel protein protein. 31 5.0
AL355372-1|CAI16402.1| 1044|Homo sapiens novel protein protein. 31 5.0
Z19054-1|CAA79497.1| 781|Homo sapiens beta catenin protein. 31 6.7
X87838-1|CAA61107.1| 781|Homo sapiens beta-catenin protein. 31 6.7
X07290-1|CAA30269.1| 195|Homo sapiens protein ( Human HF.12 gen... 31 6.7
U72069-1|AAB58254.1| 890|Homo sapiens karyopherin beta2 protein. 31 6.7
U70322-1|AAC50723.1| 890|Homo sapiens transportin protein. 31 6.7
BT006918-1|AAP35564.1| 410|Homo sapiens zinc finger protein 3 (... 31 6.7
BC058926-1|AAH58926.1| 781|Homo sapiens catenin (cadherin-assoc... 31 6.7
BC040340-1|AAH40340.1| 890|Homo sapiens transportin 1 protein. 31 6.7
BC025265-1|AAH25265.1| 410|Homo sapiens ZNF3 protein protein. 31 6.7
BC013603-1|AAH13603.1| 410|Homo sapiens ZNF3 protein protein. 31 6.7
BC011887-1|AAH11887.2| 446|Homo sapiens zinc finger protein 3 p... 31 6.7
AY463360-1|AAR18817.1| 781|Homo sapiens catenin (cadherin-assoc... 31 6.7
AK000223-1|BAA91019.1| 387|Homo sapiens protein ( Homo sapiens ... 31 6.7
AB062292-1|BAB93475.1| 511|Homo sapiens catenin beta 1 protein. 31 6.7
Z73678-1|CAA98022.1| 726|Homo sapiens plakophilin 1 protein. 30 8.8
Z34974-1|CAA84426.1| 726|Homo sapiens plakophilin protein. 30 8.8
X79293-1|CAA55881.1| 725|Homo sapiens band-6-protein protein. 30 8.8
BC117686-1|AAI17687.1| 1683|Homo sapiens SHPRH protein protein. 30 8.8
BC117685-1|AAI17686.1| 155|Homo sapiens SHPRH protein protein. 30 8.8
BC114571-1|AAI14572.1| 726|Homo sapiens plakophilin 1 (ectoderm... 30 8.8
BC113089-1|AAI13090.1| 155|Homo sapiens SHPRH protein protein. 30 8.8
BC026158-1|AAH26158.1| 1315|Homo sapiens serine/threonine kinase... 30 8.8
AY163808-1|AAO06907.1| 1659|Homo sapiens helicase-like protein p... 30 8.8
AY161136-1|AAO26201.1| 1683|Homo sapiens SNF2 histone linker PHD... 30 8.8
AL451145-1|CAH70765.1| 1683|Homo sapiens SNF2 histone linker PHD... 30 8.8
AL356599-2|CAI41120.1| 1683|Homo sapiens SNF2 histone linker PHD... 30 8.8
AK075318-1|BAC11544.1| 584|Homo sapiens protein ( Homo sapiens ... 30 8.8
AK022692-1|BAB14184.1| 360|Homo sapiens protein ( Homo sapiens ... 30 8.8
AF200815-1|AAF97028.1| 1315|Homo sapiens FUSED serine/threonine ... 30 8.8
AB033104-1|BAA86592.1| 1311|Homo sapiens KIAA1278 protein protein. 30 8.8
>BC024202-1|AAH24202.1| 521|Homo sapiens karyopherin alpha 3
(importin alpha 4) protein.
Length = 521
Score = 388 bits (954), Expect = e-107
Identities = 182/268 (67%), Positives = 218/268 (81%), Gaps = 1/268 (0%)
Frame = +3
Query: 21 NRMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPISYSTDEEEIDKNLATT 200
+R+ FKN G+DV+ MRR RNEVTVELRKNKR+E L K+RNVP S ++ ++D +
Sbjct: 10 HRIKSFKNKGRDVETMRRHRNEVTVELRKNKRDEHLLKKRNVPQEESLEDSDVDADFKAQ 69
Query: 201 DLD-ELVMNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNP 377
++ E ++ A ++NP QL+AVQ RKLLS D+NPPID+LI +GILPILV+CL R DNP
Sbjct: 70 NVTLEAILQNATSDNPVVQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVKCLERDDNP 129
Query: 378 ALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGP 557
+LQFE AWALTNIASGTSAQT VV + AVP+FL+LL SPH+NVC+QAVWALGNIIGDGP
Sbjct: 130 SLQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQNVCEQAVWALGNIIGDGP 189
Query: 558 VLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTWVIVNLCRSKDPPPPLKTIQEILPALNV 737
RD+VI LGVVKPLLS I IPI FLRNVTWVIVNLCR+KDPPPP++T+QEILPAL V
Sbjct: 190 QCRDYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQEILPALCV 249
Query: 738 LILHNDSSVLVDTVWAIXYLTDGGNEQI 821
LI H D ++LVDTVWA+ YLTDGGNEQI
Sbjct: 250 LIYHTDINILVDTVWALSYLTDGGNEQI 277
Score = 60.1 bits (139), Expect = 1e-08
Identities = 49/159 (30%), Positives = 72/159 (45%), Gaps = 3/159 (1%)
Frame = +3
Query: 300 NPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFL 479
N I +I +G++P LV LS + +Q A+ NI +GT QT V++ + F
Sbjct: 274 NEQIQMVIDSGVVPFLVPLLSHQE-VKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFP 332
Query: 480 QLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLL-SLIKSDIPIPFLRNVTW 656
LL P E + +AVW L NI VI+ G++ ++ L K D + W
Sbjct: 333 NLLSHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQ--KEAAW 390
Query: 657 VIVNLCRS--KDPPPPLKTIQEILPALNVLILHNDSSVL 767
I NL S KD L Q ++P L+ DS V+
Sbjct: 391 AISNLTISGRKDQVEYL-VQQNVIPPFCNLLSVKDSQVV 428
Score = 40.7 bits (91), Expect = 0.006
Identities = 33/170 (19%), Positives = 61/170 (35%)
Frame = +3
Query: 312 DELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLM 491
D +I+ G++ L+ +S + W + N+ +P L+
Sbjct: 193 DYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQEILPALCVLIY 252
Query: 492 SPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTWVIVNL 671
N+ VWAL + G VI+ GVV P L + S + + N+
Sbjct: 253 HTDINILVDTVWALSYLTDGGNEQIQMVIDSGVV-PFLVPLLSHQEVKVQTAALRAVGNI 311
Query: 672 CRSKDPPPPLKTIQEILPALNVLILHNDSSVLVDTVWAIXYLTDGGNEQI 821
D + ++L L+ H + + VW + +T G +Q+
Sbjct: 312 VTGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWFLSNITAGNQQQV 361
>BC017355-1|AAH17355.1| 521|Homo sapiens karyopherin alpha 3
(importin alpha 4) protein.
Length = 521
Score = 388 bits (954), Expect = e-107
Identities = 182/268 (67%), Positives = 218/268 (81%), Gaps = 1/268 (0%)
Frame = +3
Query: 21 NRMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPISYSTDEEEIDKNLATT 200
+R+ FKN G+DV+ MRR RNEVTVELRKNKR+E L K+RNVP S ++ ++D +
Sbjct: 10 HRIKSFKNKGRDVETMRRHRNEVTVELRKNKRDEHLLKKRNVPQEESLEDSDVDADFKAQ 69
Query: 201 DLD-ELVMNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNP 377
++ E ++ A ++NP QL+AVQ RKLLS D+NPPID+LI +GILPILV+CL R DNP
Sbjct: 70 NVTLEAILQNATSDNPVVQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVKCLERDDNP 129
Query: 378 ALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGP 557
+LQFE AWALTNIASGTSAQT VV + AVP+FL+LL SPH+NVC+QAVWALGNIIGDGP
Sbjct: 130 SLQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQNVCEQAVWALGNIIGDGP 189
Query: 558 VLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTWVIVNLCRSKDPPPPLKTIQEILPALNV 737
RD+VI LGVVKPLLS I IPI FLRNVTWVIVNLCR+KDPPPP++T+QEILPAL V
Sbjct: 190 QCRDYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQEILPALCV 249
Query: 738 LILHNDSSVLVDTVWAIXYLTDGGNEQI 821
LI H D ++LVDTVWA+ YLTDGGNEQI
Sbjct: 250 LIYHTDINILVDTVWALSYLTDGGNEQI 277
Score = 60.1 bits (139), Expect = 1e-08
Identities = 49/159 (30%), Positives = 72/159 (45%), Gaps = 3/159 (1%)
Frame = +3
Query: 300 NPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFL 479
N I +I +G++P LV LS + +Q A+ NI +GT QT V++ + F
Sbjct: 274 NEQIQMVIDSGVVPFLVPLLSHQE-VKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFP 332
Query: 480 QLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLL-SLIKSDIPIPFLRNVTW 656
LL P E + +AVW L NI VI+ G++ ++ L K D + W
Sbjct: 333 NLLSHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQ--KEAAW 390
Query: 657 VIVNLCRS--KDPPPPLKTIQEILPALNVLILHNDSSVL 767
I NL S KD L Q ++P L+ DS V+
Sbjct: 391 AISNLTISGRKDQVEYL-VQQNVIPPFCNLLSVKDSQVV 428
Score = 40.7 bits (91), Expect = 0.006
Identities = 33/170 (19%), Positives = 61/170 (35%)
Frame = +3
Query: 312 DELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLM 491
D +I+ G++ L+ +S + W + N+ +P L+
Sbjct: 193 DYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQEILPALCVLIY 252
Query: 492 SPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTWVIVNL 671
N+ VWAL + G VI+ GVV P L + S + + N+
Sbjct: 253 HTDINILVDTVWALSYLTDGGNEQIQMVIDSGVV-PFLVPLLSHQEVKVQTAALRAVGNI 311
Query: 672 CRSKDPPPPLKTIQEILPALNVLILHNDSSVLVDTVWAIXYLTDGGNEQI 821
D + ++L L+ H + + VW + +T G +Q+
Sbjct: 312 VTGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWFLSNITAGNQQQV 361
>AL136301-1|CAH71145.1| 521|Homo sapiens karyopherin alpha 3
(importin alpha 4) protein.
Length = 521
Score = 388 bits (954), Expect = e-107
Identities = 182/268 (67%), Positives = 218/268 (81%), Gaps = 1/268 (0%)
Frame = +3
Query: 21 NRMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPISYSTDEEEIDKNLATT 200
+R+ FKN G+DV+ MRR RNEVTVELRKNKR+E L K+RNVP S ++ ++D +
Sbjct: 10 HRIKSFKNKGRDVETMRRHRNEVTVELRKNKRDEHLLKKRNVPQEESLEDSDVDADFKAQ 69
Query: 201 DLD-ELVMNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNP 377
++ E ++ A ++NP QL+AVQ RKLLS D+NPPID+LI +GILPILV+CL R DNP
Sbjct: 70 NVTLEAILQNATSDNPVVQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVKCLERDDNP 129
Query: 378 ALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGP 557
+LQFE AWALTNIASGTSAQT VV + AVP+FL+LL SPH+NVC+QAVWALGNIIGDGP
Sbjct: 130 SLQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQNVCEQAVWALGNIIGDGP 189
Query: 558 VLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTWVIVNLCRSKDPPPPLKTIQEILPALNV 737
RD+VI LGVVKPLLS I IPI FLRNVTWVIVNLCR+KDPPPP++T+QEILPAL V
Sbjct: 190 QCRDYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQEILPALCV 249
Query: 738 LILHNDSSVLVDTVWAIXYLTDGGNEQI 821
LI H D ++LVDTVWA+ YLTDGGNEQI
Sbjct: 250 LIYHTDINILVDTVWALSYLTDGGNEQI 277
Score = 60.1 bits (139), Expect = 1e-08
Identities = 49/159 (30%), Positives = 72/159 (45%), Gaps = 3/159 (1%)
Frame = +3
Query: 300 NPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFL 479
N I +I +G++P LV LS + +Q A+ NI +GT QT V++ + F
Sbjct: 274 NEQIQMVIDSGVVPFLVPLLSHQE-VKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFP 332
Query: 480 QLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLL-SLIKSDIPIPFLRNVTW 656
LL P E + +AVW L NI VI+ G++ ++ L K D + W
Sbjct: 333 NLLSHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQ--KEAAW 390
Query: 657 VIVNLCRS--KDPPPPLKTIQEILPALNVLILHNDSSVL 767
I NL S KD L Q ++P L+ DS V+
Sbjct: 391 AISNLTISGRKDQVEYL-VQQNVIPPFCNLLSVKDSQVV 428
Score = 40.7 bits (91), Expect = 0.006
Identities = 33/170 (19%), Positives = 61/170 (35%)
Frame = +3
Query: 312 DELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLM 491
D +I+ G++ L+ +S + W + N+ +P L+
Sbjct: 193 DYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQEILPALCVLIY 252
Query: 492 SPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTWVIVNL 671
N+ VWAL + G VI+ GVV P L + S + + N+
Sbjct: 253 HTDINILVDTVWALSYLTDGGNEQIQMVIDSGVV-PFLVPLLSHQEVKVQTAALRAVGNI 311
Query: 672 CRSKDPPPPLKTIQEILPALNVLILHNDSSVLVDTVWAIXYLTDGGNEQI 821
D + ++L L+ H + + VW + +T G +Q+
Sbjct: 312 VTGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWFLSNITAGNQQQV 361
>AL135901-3|CAI40716.1| 521|Homo sapiens karyopherin alpha 3
(importin alpha 4) protein.
Length = 521
Score = 388 bits (954), Expect = e-107
Identities = 182/268 (67%), Positives = 218/268 (81%), Gaps = 1/268 (0%)
Frame = +3
Query: 21 NRMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPISYSTDEEEIDKNLATT 200
+R+ FKN G+DV+ MRR RNEVTVELRKNKR+E L K+RNVP S ++ ++D +
Sbjct: 10 HRIKSFKNKGRDVETMRRHRNEVTVELRKNKRDEHLLKKRNVPQEESLEDSDVDADFKAQ 69
Query: 201 DLD-ELVMNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNP 377
++ E ++ A ++NP QL+AVQ RKLLS D+NPPID+LI +GILPILV+CL R DNP
Sbjct: 70 NVTLEAILQNATSDNPVVQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVKCLERDDNP 129
Query: 378 ALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGP 557
+LQFE AWALTNIASGTSAQT VV + AVP+FL+LL SPH+NVC+QAVWALGNIIGDGP
Sbjct: 130 SLQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQNVCEQAVWALGNIIGDGP 189
Query: 558 VLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTWVIVNLCRSKDPPPPLKTIQEILPALNV 737
RD+VI LGVVKPLLS I IPI FLRNVTWVIVNLCR+KDPPPP++T+QEILPAL V
Sbjct: 190 QCRDYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQEILPALCV 249
Query: 738 LILHNDSSVLVDTVWAIXYLTDGGNEQI 821
LI H D ++LVDTVWA+ YLTDGGNEQI
Sbjct: 250 LIYHTDINILVDTVWALSYLTDGGNEQI 277
Score = 60.1 bits (139), Expect = 1e-08
Identities = 49/159 (30%), Positives = 72/159 (45%), Gaps = 3/159 (1%)
Frame = +3
Query: 300 NPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFL 479
N I +I +G++P LV LS + +Q A+ NI +GT QT V++ + F
Sbjct: 274 NEQIQMVIDSGVVPFLVPLLSHQE-VKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFP 332
Query: 480 QLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLL-SLIKSDIPIPFLRNVTW 656
LL P E + +AVW L NI VI+ G++ ++ L K D + W
Sbjct: 333 NLLSHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQ--KEAAW 390
Query: 657 VIVNLCRS--KDPPPPLKTIQEILPALNVLILHNDSSVL 767
I NL S KD L Q ++P L+ DS V+
Sbjct: 391 AISNLTISGRKDQVEYL-VQQNVIPPFCNLLSVKDSQVV 428
Score = 40.7 bits (91), Expect = 0.006
Identities = 33/170 (19%), Positives = 61/170 (35%)
Frame = +3
Query: 312 DELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLM 491
D +I+ G++ L+ +S + W + N+ +P L+
Sbjct: 193 DYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQEILPALCVLIY 252
Query: 492 SPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTWVIVNL 671
N+ VWAL + G VI+ GVV P L + S + + N+
Sbjct: 253 HTDINILVDTVWALSYLTDGGNEQIQMVIDSGVV-PFLVPLLSHQEVKVQTAALRAVGNI 311
Query: 672 CRSKDPPPPLKTIQEILPALNVLILHNDSSVLVDTVWAIXYLTDGGNEQI 821
D + ++L L+ H + + VW + +T G +Q+
Sbjct: 312 VTGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWFLSNITAGNQQQV 361
>AK223480-1|BAD97200.1| 521|Homo sapiens karyopherin alpha 3
variant protein.
Length = 521
Score = 388 bits (954), Expect = e-107
Identities = 182/268 (67%), Positives = 218/268 (81%), Gaps = 1/268 (0%)
Frame = +3
Query: 21 NRMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPISYSTDEEEIDKNLATT 200
+R+ FKN G+DV+ MRR RNEVTVELRKNKR+E L K+RNVP S ++ ++D +
Sbjct: 10 HRIKSFKNKGRDVETMRRHRNEVTVELRKNKRDEHLLKKRNVPQEKSLEDSDVDADFKAQ 69
Query: 201 DLD-ELVMNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNP 377
++ E ++ A ++NP QL+AVQ RKLLS D+NPPID+LI +GILPILV+CL R DNP
Sbjct: 70 NVTLEAILQNATSDNPVVQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVKCLERDDNP 129
Query: 378 ALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGP 557
+LQFE AWALTNIASGTSAQT VV + AVP+FL+LL SPH+NVC+QAVWALGNIIGDGP
Sbjct: 130 SLQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQNVCEQAVWALGNIIGDGP 189
Query: 558 VLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTWVIVNLCRSKDPPPPLKTIQEILPALNV 737
RD+VI LGVVKPLLS I IPI FLRNVTWVIVNLCR+KDPPPP++T+QEILPAL V
Sbjct: 190 QCRDYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQEILPALCV 249
Query: 738 LILHNDSSVLVDTVWAIXYLTDGGNEQI 821
LI H D ++LVDTVWA+ YLTDGGNEQI
Sbjct: 250 LIYHTDINILVDTVWALSYLTDGGNEQI 277
Score = 54.4 bits (125), Expect = 5e-07
Identities = 48/159 (30%), Positives = 71/159 (44%), Gaps = 3/159 (1%)
Frame = +3
Query: 300 NPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFL 479
N I +I +G++P LV LS + +Q A+ NI +GT QT V++ + F
Sbjct: 274 NEQIQMVIDSGVVPFLVPLLSHQE-VKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFP 332
Query: 480 QLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLL-SLIKSDIPIPFLRNVTW 656
LL P E + +AVW L NI VI+ G++ ++ L K D +
Sbjct: 333 NLLSHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQ--KEAAR 390
Query: 657 VIVNLCRS--KDPPPPLKTIQEILPALNVLILHNDSSVL 767
I NL S KD L Q ++P L+ DS V+
Sbjct: 391 AISNLTISGRKDQVEYL-VQQNVIPPFCNLLSVKDSQVV 428
Score = 40.7 bits (91), Expect = 0.006
Identities = 33/170 (19%), Positives = 61/170 (35%)
Frame = +3
Query: 312 DELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLM 491
D +I+ G++ L+ +S + W + N+ +P L+
Sbjct: 193 DYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQEILPALCVLIY 252
Query: 492 SPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTWVIVNL 671
N+ VWAL + G VI+ GVV P L + S + + N+
Sbjct: 253 HTDINILVDTVWALSYLTDGGNEQIQMVIDSGVV-PFLVPLLSHQEVKVQTAALRAVGNI 311
Query: 672 CRSKDPPPPLKTIQEILPALNVLILHNDSSVLVDTVWAIXYLTDGGNEQI 821
D + ++L L+ H + + VW + +T G +Q+
Sbjct: 312 VTGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWFLSNITAGNQQQV 361
>AF005263-1|AAQ13404.1| 521|Homo sapiens importin alpha-3 subunit
protein.
Length = 521
Score = 388 bits (954), Expect = e-107
Identities = 182/268 (67%), Positives = 218/268 (81%), Gaps = 1/268 (0%)
Frame = +3
Query: 21 NRMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPISYSTDEEEIDKNLATT 200
+R+ FKN G+DV+ MRR RNEVTVELRKNKR+E L K+RNVP S ++ ++D +
Sbjct: 10 HRIKSFKNKGRDVETMRRHRNEVTVELRKNKRDEHLLKKRNVPQEESLEDSDVDADFKAQ 69
Query: 201 DLD-ELVMNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNP 377
++ E ++ A ++NP QL+AVQ RKLLS D+NPPID+LI +GILPILV+CL R DNP
Sbjct: 70 NVTLEAILQNATSDNPVVQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVKCLERDDNP 129
Query: 378 ALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGP 557
+LQFE AWALTNIASGTSAQT VV + AVP+FL+LL SPH+NVC+QAVWALGNIIGDGP
Sbjct: 130 SLQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQNVCEQAVWALGNIIGDGP 189
Query: 558 VLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTWVIVNLCRSKDPPPPLKTIQEILPALNV 737
RD+VI LGVVKPLLS I IPI FLRNVTWVIVNLCR+KDPPPP++T+QEILPAL V
Sbjct: 190 QCRDYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQEILPALCV 249
Query: 738 LILHNDSSVLVDTVWAIXYLTDGGNEQI 821
LI H D ++LVDTVWA+ YLTDGGNEQI
Sbjct: 250 LIYHTDINILVDTVWALSYLTDGGNEQI 277
Score = 60.1 bits (139), Expect = 1e-08
Identities = 49/159 (30%), Positives = 72/159 (45%), Gaps = 3/159 (1%)
Frame = +3
Query: 300 NPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFL 479
N I +I +G++P LV LS + +Q A+ NI +GT QT V++ + F
Sbjct: 274 NEQIQMVIDSGVVPFLVPLLSHQE-VKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFP 332
Query: 480 QLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLL-SLIKSDIPIPFLRNVTW 656
LL P E + +AVW L NI VI+ G++ ++ L K D + W
Sbjct: 333 NLLSHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQ--KEAAW 390
Query: 657 VIVNLCRS--KDPPPPLKTIQEILPALNVLILHNDSSVL 767
I NL S KD L Q ++P L+ DS V+
Sbjct: 391 AISNLTISGRKDQVEYL-VQQNVIPPFCNLLSVKDSQVV 428
Score = 40.7 bits (91), Expect = 0.006
Identities = 33/170 (19%), Positives = 61/170 (35%)
Frame = +3
Query: 312 DELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLM 491
D +I+ G++ L+ +S + W + N+ +P L+
Sbjct: 193 DYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQEILPALCVLIY 252
Query: 492 SPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTWVIVNL 671
N+ VWAL + G VI+ GVV P L + S + + N+
Sbjct: 253 HTDINILVDTVWALSYLTDGGNEQIQMVIDSGVV-PFLVPLLSHQEVKVQTAALRAVGNI 311
Query: 672 CRSKDPPPPLKTIQEILPALNVLILHNDSSVLVDTVWAIXYLTDGGNEQI 821
D + ++L L+ H + + VW + +T G +Q+
Sbjct: 312 VTGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWFLSNITAGNQQQV 361
>D89618-1|BAA20378.1| 521|Homo sapiens karyopherin alhph 3 protein.
Length = 521
Score = 387 bits (953), Expect = e-107
Identities = 182/268 (67%), Positives = 218/268 (81%), Gaps = 1/268 (0%)
Frame = +3
Query: 21 NRMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPISYSTDEEEIDKNLATT 200
+R+ FKN G+DV+ MRR RNEVTVELRKNKR+E L K+RNVP S ++ ++D +
Sbjct: 10 HRIKSFKNKGRDVETMRRHRNEVTVELRKNKRDEHLLKKRNVPQEESLEDSDVDADFKAQ 69
Query: 201 DLD-ELVMNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNP 377
++ E ++ A ++NP QL+AVQ RKLLS D+NPPID+LI +GILPILV+CL R DNP
Sbjct: 70 NVTLEAILQNATSDNPVVQLSAVQAARKLLSSDQNPPIDDLIKSGILPILVKCLERDDNP 129
Query: 378 ALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGP 557
+LQFE AWALTNIASGTSAQT VV + AVP+FL+LL SPH+NVC+QAVWALGNIIGDGP
Sbjct: 130 SLQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQNVCEQAVWALGNIIGDGP 189
Query: 558 VLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTWVIVNLCRSKDPPPPLKTIQEILPALNV 737
RD+VI LGVVKPLLS I IPI FLRNVTWVIVNLCR+KDPPPP++T+QEILPAL V
Sbjct: 190 QCRDYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQEILPALCV 249
Query: 738 LILHNDSSVLVDTVWAIXYLTDGGNEQI 821
LI H D ++LVDTVWA+ YLTDGGNEQI
Sbjct: 250 LIYHTDINILVDTVWALSYLTDGGNEQI 277
Score = 60.1 bits (139), Expect = 1e-08
Identities = 49/159 (30%), Positives = 72/159 (45%), Gaps = 3/159 (1%)
Frame = +3
Query: 300 NPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFL 479
N I +I +G++P LV LS + +Q A+ NI +GT QT V++ + F
Sbjct: 274 NEQIQMVIDSGVVPFLVPLLSHQE-VKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFP 332
Query: 480 QLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLL-SLIKSDIPIPFLRNVTW 656
LL P E + +AVW L NI VI+ G++ ++ L K D + W
Sbjct: 333 NLLSHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQ--KEAAW 390
Query: 657 VIVNLCRS--KDPPPPLKTIQEILPALNVLILHNDSSVL 767
I NL S KD L Q ++P L+ DS V+
Sbjct: 391 AISNLTISGRKDQVEYL-VQQNVIPPFCNLLSVKDSQVV 428
Score = 40.7 bits (91), Expect = 0.006
Identities = 33/170 (19%), Positives = 61/170 (35%)
Frame = +3
Query: 312 DELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLM 491
D +I+ G++ L+ +S + W + N+ +P L+
Sbjct: 193 DYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQEILPALCVLIY 252
Query: 492 SPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTWVIVNL 671
N+ VWAL + G VI+ GVV P L + S + + N+
Sbjct: 253 HTDINILVDTVWALSYLTDGGNEQIQMVIDSGVV-PFLVPLLSHQEVKVQTAALRAVGNI 311
Query: 672 CRSKDPPPPLKTIQEILPALNVLILHNDSSVLVDTVWAIXYLTDGGNEQI 821
D + ++L L+ H + + VW + +T G +Q+
Sbjct: 312 VTGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWFLSNITAGNQQQV 361
>BC035090-1|AAH35090.1| 521|Homo sapiens karyopherin alpha 3
(importin alpha 4) protein.
Length = 521
Score = 387 bits (953), Expect = e-107
Identities = 181/268 (67%), Positives = 218/268 (81%), Gaps = 1/268 (0%)
Frame = +3
Query: 21 NRMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPISYSTDEEEIDKNLATT 200
+R+ FKN G+DV+ MRR RNEVTVELRKNKR+E L K+RNVP S ++ ++D +
Sbjct: 10 HRIKSFKNKGRDVETMRRHRNEVTVELRKNKRDEHLLKKRNVPQEESLEDSDVDADFKAQ 69
Query: 201 DLD-ELVMNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNP 377
++ E ++ A ++NP QL+AVQ RKLLS D+NPPID+LI +GILPILV+CL R DNP
Sbjct: 70 NVTLEAILQNATSDNPVVQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVKCLERDDNP 129
Query: 378 ALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGP 557
+LQFE AWALTNIASGTSAQT +V + AVP+FL+LL SPH+NVC+QAVWALGNIIGDGP
Sbjct: 130 SLQFEAAWALTNIASGTSAQTQDIVQSNAVPLFLRLLRSPHQNVCEQAVWALGNIIGDGP 189
Query: 558 VLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTWVIVNLCRSKDPPPPLKTIQEILPALNV 737
RD+VI LGVVKPLLS I IPI FLRNVTWVIVNLCR+KDPPPP++T+QEILPAL V
Sbjct: 190 QCRDYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQEILPALCV 249
Query: 738 LILHNDSSVLVDTVWAIXYLTDGGNEQI 821
LI H D ++LVDTVWA+ YLTDGGNEQI
Sbjct: 250 LIYHTDINILVDTVWALSYLTDGGNEQI 277
Score = 61.3 bits (142), Expect = 4e-09
Identities = 49/159 (30%), Positives = 73/159 (45%), Gaps = 3/159 (1%)
Frame = +3
Query: 300 NPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFL 479
N I +I +G++P LV LS + +Q A+ NI +GT QT V++ + F
Sbjct: 274 NEQIQMVIDSGVVPFLVPLLSHQE-VKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFQ 332
Query: 480 QLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLL-SLIKSDIPIPFLRNVTW 656
LL P E + +AVW L NI VI+ G++ ++ L K D + W
Sbjct: 333 NLLSHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQ--KEAAW 390
Query: 657 VIVNLCRS--KDPPPPLKTIQEILPALNVLILHNDSSVL 767
I NL S KD L Q+++P L+ DS V+
Sbjct: 391 AISNLTISGRKDQVEYL-VQQDVIPPFCNLLSVKDSQVV 428
Score = 41.5 bits (93), Expect = 0.004
Identities = 33/170 (19%), Positives = 61/170 (35%)
Frame = +3
Query: 312 DELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLM 491
D +I+ G++ L+ +S + W + N+ +P L+
Sbjct: 193 DYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQEILPALCVLIY 252
Query: 492 SPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTWVIVNL 671
N+ VWAL + G VI+ GVV P L + S + + N+
Sbjct: 253 HTDINILVDTVWALSYLTDGGNEQIQMVIDSGVV-PFLVPLLSHQEVKVQTAALRAVGNI 311
Query: 672 CRSKDPPPPLKTIQEILPALNVLILHNDSSVLVDTVWAIXYLTDGGNEQI 821
D + ++L L+ H + + VW + +T G +Q+
Sbjct: 312 VTGTDEQTQVVLNCDVLSHFQNLLSHPKEKINKEAVWFLSNITAGNQQQV 361
>Y12394-1|CAA73026.1| 521|Homo sapiens SRP1-like protein protein.
Length = 521
Score = 386 bits (950), Expect = e-107
Identities = 181/268 (67%), Positives = 218/268 (81%), Gaps = 1/268 (0%)
Frame = +3
Query: 21 NRMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPISYSTDEEEIDKNLATT 200
+R+ FKN G+DV+ MRR RNEVT+ELRKNKR+E L K+RNVP S ++ ++D +
Sbjct: 10 HRIKSFKNKGRDVETMRRHRNEVTMELRKNKRDEHLLKKRNVPQEESLEDSDVDADFKAQ 69
Query: 201 DLD-ELVMNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNP 377
++ E ++ A ++NP QL+AVQ RKLLS D+NPPID+LI +GILPILV+CL R DNP
Sbjct: 70 NVTLEAILQNATSDNPVVQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVKCLERDDNP 129
Query: 378 ALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGP 557
+LQFE AWALTNIASGTSAQT VV + AVP+FL+LL SPH+NVC+QAVWALGNIIGDGP
Sbjct: 130 SLQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQNVCEQAVWALGNIIGDGP 189
Query: 558 VLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTWVIVNLCRSKDPPPPLKTIQEILPALNV 737
RD+VI LGVVKPLLS I IPI FLRNVTWVIVNLCR+KDPPPPL+T+QEILPAL V
Sbjct: 190 QCRDYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPPLETVQEILPALCV 249
Query: 738 LILHNDSSVLVDTVWAIXYLTDGGNEQI 821
LI H D +++VDTVWA+ YLTDGGNEQI
Sbjct: 250 LIYHTDVNIVVDTVWALSYLTDGGNEQI 277
Score = 60.1 bits (139), Expect = 1e-08
Identities = 49/159 (30%), Positives = 72/159 (45%), Gaps = 3/159 (1%)
Frame = +3
Query: 300 NPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFL 479
N I +I +G++P LV LS + +Q A+ NI +GT QT V++ + F
Sbjct: 274 NEQIQMVIDSGVVPFLVPLLSHQE-VKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFP 332
Query: 480 QLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLL-SLIKSDIPIPFLRNVTW 656
LL P E + +AVW L NI VI+ G++ ++ L K D + W
Sbjct: 333 NLLSHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQ--KEAAW 390
Query: 657 VIVNLCRS--KDPPPPLKTIQEILPALNVLILHNDSSVL 767
I NL S KD L Q ++P L+ DS V+
Sbjct: 391 AISNLTISGRKDQVEYL-VQQNVIPPFCNLLSVKDSQVV 428
Score = 40.7 bits (91), Expect = 0.006
Identities = 33/170 (19%), Positives = 61/170 (35%)
Frame = +3
Query: 312 DELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLM 491
D +I+ G++ L+ +S + W + N+ +P L+
Sbjct: 193 DYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPPLETVQEILPALCVLIY 252
Query: 492 SPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTWVIVNL 671
N+ VWAL + G VI+ GVV P L + S + + N+
Sbjct: 253 HTDVNIVVDTVWALSYLTDGGNEQIQMVIDSGVV-PFLVPLLSHQEVKVQTAALRAVGNI 311
Query: 672 CRSKDPPPPLKTIQEILPALNVLILHNDSSVLVDTVWAIXYLTDGGNEQI 821
D + ++L L+ H + + VW + +T G +Q+
Sbjct: 312 VTGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWFLSNITAGNQQQV 361
>AF034756-1|AAB87693.1| 521|Homo sapiens importin-alpha homolog
protein.
Length = 521
Score = 382 bits (939), Expect = e-105
Identities = 180/268 (67%), Positives = 216/268 (80%), Gaps = 1/268 (0%)
Frame = +3
Query: 21 NRMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPISYSTDEEEIDKNLATT 200
+R+ FKN G+DV+ MRR RNEVTVELRKNKR+E L K+RNVP S ++ ++D +
Sbjct: 10 HRIKSFKNKGRDVETMRRHRNEVTVELRKNKRDEHLLKKRNVPQEESLEDSDVDADFKAQ 69
Query: 201 DLD-ELVMNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNP 377
++ E ++ A ++NP QL+AVQ RKLLS D+NPPID+LI +GILPILV+CL R DNP
Sbjct: 70 NVTLEAILQNATSDNPVVQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVKCLERDDNP 129
Query: 378 ALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGP 557
+LQFE AWALTNIASGTSAQT V + AVP+FL+LL SPH+NVC+QAVWALGNIIGDGP
Sbjct: 130 SLQFEAAWALTNIASGTSAQTQAVGQSNAVPLFLRLLRSPHQNVCEQAVWALGNIIGDGP 189
Query: 558 VLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTWVIVNLCRSKDPPPPLKTIQEILPALNV 737
RD+VI LGVVKPLLS I IPI FLRNVTWVIVNLCR+KDPPP ++T+QEILPAL V
Sbjct: 190 QCRDYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPTMETVQEILPALCV 249
Query: 738 LILHNDSSVLVDTVWAIXYLTDGGNEQI 821
LI H D ++LVDTVWA+ YLTDGGNEQI
Sbjct: 250 LIYHTDINILVDTVWALSYLTDGGNEQI 277
Score = 60.1 bits (139), Expect = 1e-08
Identities = 49/159 (30%), Positives = 72/159 (45%), Gaps = 3/159 (1%)
Frame = +3
Query: 300 NPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFL 479
N I +I +G++P LV LS + +Q A+ NI +GT QT V++ + F
Sbjct: 274 NEQIQMVIDSGVVPFLVPLLSHQE-VKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFP 332
Query: 480 QLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLL-SLIKSDIPIPFLRNVTW 656
LL P E + +AVW L NI VI+ G++ ++ L K D + W
Sbjct: 333 NLLSHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQ--KEAAW 390
Query: 657 VIVNLCRS--KDPPPPLKTIQEILPALNVLILHNDSSVL 767
I NL S KD L Q ++P L+ DS V+
Sbjct: 391 AISNLTISGRKDQVEYL-VQQNVIPPFCNLLSVKDSQVV 428
Score = 41.5 bits (93), Expect = 0.004
Identities = 33/170 (19%), Positives = 61/170 (35%)
Frame = +3
Query: 312 DELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLM 491
D +I+ G++ L+ +S + W + N+ +P L+
Sbjct: 193 DYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPTMETVQEILPALCVLIY 252
Query: 492 SPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTWVIVNL 671
N+ VWAL + G VI+ GVV P L + S + + N+
Sbjct: 253 HTDINILVDTVWALSYLTDGGNEQIQMVIDSGVV-PFLVPLLSHQEVKVQTAALRAVGNI 311
Query: 672 CRSKDPPPPLKTIQEILPALNVLILHNDSSVLVDTVWAIXYLTDGGNEQI 821
D + ++L L+ H + + VW + +T G +Q+
Sbjct: 312 VTGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWFLSNITAGNQQQV 361
>U93240-1|AAC25605.1| 521|Homo sapiens importin alpha 3 protein.
Length = 521
Score = 373 bits (918), Expect = e-103
Identities = 181/268 (67%), Positives = 214/268 (79%), Gaps = 2/268 (0%)
Frame = +3
Query: 24 RMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPISYSTDEEEIDKN--LAT 197
R+ FKN G+D++ MRR+RNEV VELRKNKR+E L KRRNVP ++ +ID + +
Sbjct: 11 RLKNFKNKGRDLETMRRQRNEVVVELRKNKRDEHLLKRRNVPHEDICEDSDIDGDYRVQN 70
Query: 198 TDLDELVMNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNP 377
T L+ +V NA++ +N QL+AVQ RKLLS D+NPPID+LI +GILPILV CL R DNP
Sbjct: 71 TSLEAIVQNASS-DNQGIQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVHCLERDDNP 129
Query: 378 ALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGP 557
+LQFE AWALTNIASGTS QT VV + AVP+FL+LL SPH+NVC+QAVWALGNIIGDGP
Sbjct: 130 SLQFEAAWALTNIASGTSEQTQAVVQSNAVPLFLRLLHSPHQNVCEQAVWALGNIIGDGP 189
Query: 558 VLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTWVIVNLCRSKDPPPPLKTIQEILPALNV 737
RD+VI LGVVKPLLS I IPI FLRNVTWV+VNLCR KDPPPP++TIQEILPAL V
Sbjct: 190 QCRDYVISLGVVKPLLSFISPSIPITFLRNVTWVMVNLCRHKDPPPPMETIQEILPALCV 249
Query: 738 LILHNDSSVLVDTVWAIXYLTDGGNEQI 821
LI H D ++LVDTVWA+ YLTD GNEQI
Sbjct: 250 LIHHTDVNILVDTVWALSYLTDAGNEQI 277
Score = 58.8 bits (136), Expect = 2e-08
Identities = 48/158 (30%), Positives = 72/158 (45%), Gaps = 2/158 (1%)
Frame = +3
Query: 300 NPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFL 479
N I +I +GI+P LV LS + +Q A+ NI +GT QT V++ A+ F
Sbjct: 274 NEQIQMVIDSGIVPHLVPLLSHQE-VKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFP 332
Query: 480 QLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLI-KSDIPIPFLRNVTW 656
LL P E + +AVW L NI VI+ +V ++ L+ K D + W
Sbjct: 333 ALLTHPKEKINKEAVWFLSNITAGNQQQVQAVIDANLVPMIIHLLDKGDFGTQ--KEAAW 390
Query: 657 VIVNLCRSKDPPPPLKTIQE-ILPALNVLILHNDSSVL 767
I NL S IQ+ ++P L+ D+ V+
Sbjct: 391 AISNLTISGRKDQVAYLIQQNVIPPFCNLLTVKDAQVV 428
Score = 39.5 bits (88), Expect = 0.014
Identities = 32/170 (18%), Positives = 61/170 (35%)
Frame = +3
Query: 312 DELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLM 491
D +I+ G++ L+ +S + W + N+ +P L+
Sbjct: 193 DYVISLGVVKPLLSFISPSIPITFLRNVTWVMVNLCRHKDPPPPMETIQEILPALCVLIH 252
Query: 492 SPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTWVIVNL 671
N+ VWAL + G VI+ G+V L+ L+ S + + N+
Sbjct: 253 HTDVNILVDTVWALSYLTDAGNEQIQMVIDSGIVPHLVPLL-SHQEVKVQTAALRAVGNI 311
Query: 672 CRSKDPPPPLKTIQEILPALNVLILHNDSSVLVDTVWAIXYLTDGGNEQI 821
D + + L L+ H + + VW + +T G +Q+
Sbjct: 312 VTGTDEQTQVVLNCDALSHFPALLTHPKEKINKEAVWFLSNITAGNQQQV 361
>BC034493-1|AAH34493.1| 521|Homo sapiens karyopherin alpha 4
(importin alpha 3) protein.
Length = 521
Score = 373 bits (918), Expect = e-103
Identities = 181/268 (67%), Positives = 214/268 (79%), Gaps = 2/268 (0%)
Frame = +3
Query: 24 RMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPISYSTDEEEIDKN--LAT 197
R+ FKN G+D++ MRR+RNEV VELRKNKR+E L KRRNVP ++ +ID + +
Sbjct: 11 RLKNFKNKGRDLETMRRQRNEVVVELRKNKRDEHLLKRRNVPHEDICEDSDIDGDYRVQN 70
Query: 198 TDLDELVMNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNP 377
T L+ +V NA++ +N QL+AVQ RKLLS D+NPPID+LI +GILPILV CL R DNP
Sbjct: 71 TSLEAIVQNASS-DNQGIQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVHCLERDDNP 129
Query: 378 ALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGP 557
+LQFE AWALTNIASGTS QT VV + AVP+FL+LL SPH+NVC+QAVWALGNIIGDGP
Sbjct: 130 SLQFEAAWALTNIASGTSEQTQAVVQSNAVPLFLRLLHSPHQNVCEQAVWALGNIIGDGP 189
Query: 558 VLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTWVIVNLCRSKDPPPPLKTIQEILPALNV 737
RD+VI LGVVKPLLS I IPI FLRNVTWV+VNLCR KDPPPP++TIQEILPAL V
Sbjct: 190 QCRDYVISLGVVKPLLSFISPSIPITFLRNVTWVMVNLCRHKDPPPPMETIQEILPALCV 249
Query: 738 LILHNDSSVLVDTVWAIXYLTDGGNEQI 821
LI H D ++LVDTVWA+ YLTD GNEQI
Sbjct: 250 LIHHTDVNILVDTVWALSYLTDAGNEQI 277
Score = 58.8 bits (136), Expect = 2e-08
Identities = 48/158 (30%), Positives = 72/158 (45%), Gaps = 2/158 (1%)
Frame = +3
Query: 300 NPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFL 479
N I +I +GI+P LV LS + +Q A+ NI +GT QT V++ A+ F
Sbjct: 274 NEQIQMVIDSGIVPHLVPLLSHQE-VKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFP 332
Query: 480 QLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLI-KSDIPIPFLRNVTW 656
LL P E + +AVW L NI VI+ +V ++ L+ K D + W
Sbjct: 333 ALLTHPKEKINKEAVWFLSNITAGNQQQVQAVIDANLVPMIIHLLDKGDFGTQ--KEAAW 390
Query: 657 VIVNLCRSKDPPPPLKTIQE-ILPALNVLILHNDSSVL 767
I NL S IQ+ ++P L+ D+ V+
Sbjct: 391 AISNLTISGRKDQVAYLIQQNVIPPFCNLLTVKDAQVV 428
Score = 39.5 bits (88), Expect = 0.014
Identities = 32/170 (18%), Positives = 61/170 (35%)
Frame = +3
Query: 312 DELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLM 491
D +I+ G++ L+ +S + W + N+ +P L+
Sbjct: 193 DYVISLGVVKPLLSFISPSIPITFLRNVTWVMVNLCRHKDPPPPMETIQEILPALCVLIH 252
Query: 492 SPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTWVIVNL 671
N+ VWAL + G VI+ G+V L+ L+ S + + N+
Sbjct: 253 HTDVNILVDTVWALSYLTDAGNEQIQMVIDSGIVPHLVPLL-SHQEVKVQTAALRAVGNI 311
Query: 672 CRSKDPPPPLKTIQEILPALNVLILHNDSSVLVDTVWAIXYLTDGGNEQI 821
D + + L L+ H + + VW + +T G +Q+
Sbjct: 312 VTGTDEQTQVVLNCDALSHFPALLTHPKEKINKEAVWFLSNITAGNQQQV 361
>BC028691-1|AAH28691.1| 521|Homo sapiens karyopherin alpha 4
(importin alpha 3) protein.
Length = 521
Score = 373 bits (918), Expect = e-103
Identities = 181/268 (67%), Positives = 214/268 (79%), Gaps = 2/268 (0%)
Frame = +3
Query: 24 RMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPISYSTDEEEIDKN--LAT 197
R+ FKN G+D++ MRR+RNEV VELRKNKR+E L KRRNVP ++ +ID + +
Sbjct: 11 RLKNFKNKGRDLETMRRQRNEVVVELRKNKRDEHLLKRRNVPHEDICEDSDIDGDYRVQN 70
Query: 198 TDLDELVMNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNP 377
T L+ +V NA++ +N QL+AVQ RKLLS D+NPPID+LI +GILPILV CL R DNP
Sbjct: 71 TSLEAIVQNASS-DNQGIQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVHCLERDDNP 129
Query: 378 ALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGP 557
+LQFE AWALTNIASGTS QT VV + AVP+FL+LL SPH+NVC+QAVWALGNIIGDGP
Sbjct: 130 SLQFEAAWALTNIASGTSEQTQAVVQSNAVPLFLRLLHSPHQNVCEQAVWALGNIIGDGP 189
Query: 558 VLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTWVIVNLCRSKDPPPPLKTIQEILPALNV 737
RD+VI LGVVKPLLS I IPI FLRNVTWV+VNLCR KDPPPP++TIQEILPAL V
Sbjct: 190 QCRDYVISLGVVKPLLSFISPSIPITFLRNVTWVMVNLCRHKDPPPPMETIQEILPALCV 249
Query: 738 LILHNDSSVLVDTVWAIXYLTDGGNEQI 821
LI H D ++LVDTVWA+ YLTD GNEQI
Sbjct: 250 LIHHTDVNILVDTVWALSYLTDAGNEQI 277
Score = 58.8 bits (136), Expect = 2e-08
Identities = 48/158 (30%), Positives = 72/158 (45%), Gaps = 2/158 (1%)
Frame = +3
Query: 300 NPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFL 479
N I +I +GI+P LV LS + +Q A+ NI +GT QT V++ A+ F
Sbjct: 274 NEQIQMVIDSGIVPHLVPLLSHQE-VKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFP 332
Query: 480 QLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLI-KSDIPIPFLRNVTW 656
LL P E + +AVW L NI VI+ +V ++ L+ K D + W
Sbjct: 333 ALLTHPKEKINKEAVWFLSNITAGNQQQVQAVIDANLVPMIIHLLDKGDFGTQ--KEAAW 390
Query: 657 VIVNLCRSKDPPPPLKTIQE-ILPALNVLILHNDSSVL 767
I NL S IQ+ ++P L+ D+ V+
Sbjct: 391 AISNLTISGRKDQVAYLIQQNVIPPFCNLLTVKDAQVV 428
Score = 39.5 bits (88), Expect = 0.014
Identities = 32/170 (18%), Positives = 61/170 (35%)
Frame = +3
Query: 312 DELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLM 491
D +I+ G++ L+ +S + W + N+ +P L+
Sbjct: 193 DYVISLGVVKPLLSFISPSIPITFLRNVTWVMVNLCRHKDPPPPMETIQEILPALCVLIH 252
Query: 492 SPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTWVIVNL 671
N+ VWAL + G VI+ G+V L+ L+ S + + N+
Sbjct: 253 HTDVNILVDTVWALSYLTDAGNEQIQMVIDSGIVPHLVPLL-SHQEVKVQTAALRAVGNI 311
Query: 672 CRSKDPPPPLKTIQEILPALNVLILHNDSSVLVDTVWAIXYLTDGGNEQI 821
D + + L L+ H + + VW + +T G +Q+
Sbjct: 312 VTGTDEQTQVVLNCDALSHFPALLTHPKEKINKEAVWFLSNITAGNQQQV 361
>AB002533-1|BAA19546.1| 521|Homo sapiens Qip1 protein.
Length = 521
Score = 373 bits (918), Expect = e-103
Identities = 181/268 (67%), Positives = 214/268 (79%), Gaps = 2/268 (0%)
Frame = +3
Query: 24 RMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPISYSTDEEEIDKN--LAT 197
R+ FKN G+D++ MRR+RNEV VELRKNKR+E L KRRNVP ++ +ID + +
Sbjct: 11 RLKNFKNKGRDLETMRRQRNEVVVELRKNKRDEHLLKRRNVPHEDICEDSDIDGDYRVQN 70
Query: 198 TDLDELVMNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNP 377
T L+ +V NA++ +N QL+AVQ RKLLS D+NPPID+LI +GILPILV CL R DNP
Sbjct: 71 TSLEAIVQNASS-DNQGIQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVHCLERDDNP 129
Query: 378 ALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGP 557
+LQFE AWALTNIASGTS QT VV + AVP+FL+LL SPH+NVC+QAVWALGNIIGDGP
Sbjct: 130 SLQFEAAWALTNIASGTSEQTQAVVQSNAVPLFLRLLHSPHQNVCEQAVWALGNIIGDGP 189
Query: 558 VLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTWVIVNLCRSKDPPPPLKTIQEILPALNV 737
RD+VI LGVVKPLLS I IPI FLRNVTWV+VNLCR KDPPPP++TIQEILPAL V
Sbjct: 190 QCRDYVISLGVVKPLLSFISPSIPITFLRNVTWVMVNLCRHKDPPPPMETIQEILPALCV 249
Query: 738 LILHNDSSVLVDTVWAIXYLTDGGNEQI 821
LI H D ++LVDTVWA+ YLTD GNEQI
Sbjct: 250 LIHHTDVNILVDTVWALSYLTDAGNEQI 277
Score = 58.8 bits (136), Expect = 2e-08
Identities = 48/158 (30%), Positives = 72/158 (45%), Gaps = 2/158 (1%)
Frame = +3
Query: 300 NPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFL 479
N I +I +GI+P LV LS + +Q A+ NI +GT QT V++ A+ F
Sbjct: 274 NEQIQMVIDSGIVPHLVPLLSHQE-VKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFP 332
Query: 480 QLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLI-KSDIPIPFLRNVTW 656
LL P E + +AVW L NI VI+ +V ++ L+ K D + W
Sbjct: 333 ALLTHPKEKINKEAVWFLSNITAGNQQQVQAVIDANLVPMIIHLLDKGDFGTQ--KEAAW 390
Query: 657 VIVNLCRSKDPPPPLKTIQE-ILPALNVLILHNDSSVL 767
I NL S IQ+ ++P L+ D+ V+
Sbjct: 391 AISNLTISGRKDQVAYLIQQNVIPPFCNLLTVKDAQVV 428
Score = 39.5 bits (88), Expect = 0.014
Identities = 32/170 (18%), Positives = 61/170 (35%)
Frame = +3
Query: 312 DELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLM 491
D +I+ G++ L+ +S + W + N+ +P L+
Sbjct: 193 DYVISLGVVKPLLSFISPSIPITFLRNVTWVMVNLCRHKDPPPPMETIQEILPALCVLIH 252
Query: 492 SPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTWVIVNL 671
N+ VWAL + G VI+ G+V L+ L+ S + + N+
Sbjct: 253 HTDVNILVDTVWALSYLTDAGNEQIQMVIDSGIVPHLVPLL-SHQEVKVQTAALRAVGNI 311
Query: 672 CRSKDPPPPLKTIQEILPALNVLILHNDSSVLVDTVWAIXYLTDGGNEQI 821
D + + L L+ H + + VW + +T G +Q+
Sbjct: 312 VTGTDEQTQVVLNCDALSHFPALLTHPKEKINKEAVWFLSNITAGNQQQV 361
>U28386-1|AAA69957.1| 529|Homo sapiens hSRP1alpha protein.
Length = 529
Score = 283 bits (694), Expect = 5e-76
Identities = 145/275 (52%), Positives = 185/275 (67%), Gaps = 9/275 (3%)
Frame = +3
Query: 24 RMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNV---PISYSTDEEEIDKNLA 194
R+H FKN GKD EMRRRR EV VELRK K+++ + KRRNV P ++ +E N
Sbjct: 13 RLHRFKNKGKDSTEMRRRRIEVNVELRKAKKDDQMLKRRNVSSFPDDATSPLQENRNNQG 72
Query: 195 TTD--LDELVMNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRA 368
T + +D++V N+ N E QL A Q RKLLS +K PPID +I AG++P V L R
Sbjct: 73 TVNWSVDDIV-KGINSSNVENQLQATQAARKLLSREKQPPIDNIIRAGLIPKFVSFLGRT 131
Query: 369 DNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIG 548
D +QFE+AWALTNIASGTS QT VV GA+P F+ LL SPH ++ +QAVWALGNI G
Sbjct: 132 DCSPIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAG 191
Query: 549 DGPVLRDFVIELGVVKPLLSLI----KSDIPIPFLRNVTWVIVNLCRSKDPPPPLKTIQE 716
DG V RD VI+ G V PLL+L+ S + +LRN+TW + NLCR+K+P PP+ +++
Sbjct: 192 DGSVFRDLVIKYGAVDPLLALLAVPDMSSLACGYLRNLTWTLSNLCRNKNPAPPIDAVEQ 251
Query: 717 ILPALNVLILHNDSSVLVDTVWAIXYLTDGGNEQI 821
ILP L L+ H+D VL DT WAI YLTDG NE+I
Sbjct: 252 ILPTLVRLLHHDDPEVLADTCWAISYLTDGPNERI 286
Score = 67.7 bits (158), Expect = 5e-11
Identities = 48/174 (27%), Positives = 79/174 (45%), Gaps = 1/174 (0%)
Frame = +3
Query: 303 PPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQ 482
PPID + ILP LV+ L D+P + +T WA++ + G + + VV G VP ++
Sbjct: 244 PPIDAV--EQILPTLVRLLHH-DDPEVLADTCWAISYLTDGPNERIGMVVKTGVVPQLVK 300
Query: 483 LLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTWVI 662
LL + + A+ A+GNI+ VI+ G + SL+ + + TW +
Sbjct: 301 LLGASELPIVTPALRAIGNIVTGTDEQTQVVIDAGALAVFPSLLTNP-KTNIQKEATWTM 359
Query: 663 VNLCRSKDPPPPLKTIQEILPALNVLILHNDSSVLVDTVWAIXYLTDGGN-EQI 821
N+ + ++P L ++ D + VWA+ T GG EQI
Sbjct: 360 SNITAGRQDQIQQVVNHGLVPFLVSVLSKADFKTQKEAVWAVTNYTSGGTVEQI 413
Score = 62.1 bits (144), Expect = 2e-09
Identities = 42/144 (29%), Positives = 66/144 (45%)
Frame = +3
Query: 237 ENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNI 416
++PE LA L+ N I ++ G++P LV+ L ++ P + A+ NI
Sbjct: 263 DDPEV-LADTCWAISYLTDGPNERIGMVVKTGVVPQLVKLLGASELPIVT-PALRAIGNI 320
Query: 417 ASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVK 596
+GT QT V+ AGA+ VF LL +P N+ +A W + NI V+ G+V
Sbjct: 321 VTGTDEQTQVVIDAGALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQVVNHGLV- 379
Query: 597 PLLSLIKSDIPIPFLRNVTWVIVN 668
P L + S + W + N
Sbjct: 380 PFLVSVLSKADFKTQKEAVWAVTN 403
>U09559-1|AAA65700.1| 529|Homo sapiens Rch1 protein.
Length = 529
Score = 283 bits (694), Expect = 5e-76
Identities = 145/275 (52%), Positives = 185/275 (67%), Gaps = 9/275 (3%)
Frame = +3
Query: 24 RMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNV---PISYSTDEEEIDKNLA 194
R+H FKN GKD EMRRRR EV VELRK K+++ + KRRNV P ++ +E N
Sbjct: 13 RLHRFKNKGKDSTEMRRRRIEVNVELRKAKKDDQMLKRRNVSSFPDDATSPLQENRNNQG 72
Query: 195 TTD--LDELVMNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRA 368
T + +D++V N+ N E QL A Q RKLLS +K PPID +I AG++P V L R
Sbjct: 73 TVNWSVDDIV-KGINSSNVENQLQATQAARKLLSREKQPPIDNIIRAGLIPKFVSFLGRT 131
Query: 369 DNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIG 548
D +QFE+AWALTNIASGTS QT VV GA+P F+ LL SPH ++ +QAVWALGNI G
Sbjct: 132 DCSPIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAG 191
Query: 549 DGPVLRDFVIELGVVKPLLSLI----KSDIPIPFLRNVTWVIVNLCRSKDPPPPLKTIQE 716
DG V RD VI+ G V PLL+L+ S + +LRN+TW + NLCR+K+P PP+ +++
Sbjct: 192 DGSVFRDLVIKYGAVDPLLALLAVPDMSSLACGYLRNLTWTLSNLCRNKNPAPPIDAVEQ 251
Query: 717 ILPALNVLILHNDSSVLVDTVWAIXYLTDGGNEQI 821
ILP L L+ H+D VL DT WAI YLTDG NE+I
Sbjct: 252 ILPTLVRLLHHDDPEVLADTCWAISYLTDGPNERI 286
Score = 67.7 bits (158), Expect = 5e-11
Identities = 48/174 (27%), Positives = 79/174 (45%), Gaps = 1/174 (0%)
Frame = +3
Query: 303 PPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQ 482
PPID + ILP LV+ L D+P + +T WA++ + G + + VV G VP ++
Sbjct: 244 PPIDAV--EQILPTLVRLLHH-DDPEVLADTCWAISYLTDGPNERIGMVVKTGVVPQLVK 300
Query: 483 LLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTWVI 662
LL + + A+ A+GNI+ VI+ G + SL+ + + TW +
Sbjct: 301 LLGASELPIVTPALRAIGNIVTGTDEQTQVVIDAGALAVFPSLLTNP-KTNIQKEATWTM 359
Query: 663 VNLCRSKDPPPPLKTIQEILPALNVLILHNDSSVLVDTVWAIXYLTDGGN-EQI 821
N+ + ++P L ++ D + VWA+ T GG EQI
Sbjct: 360 SNITAGRQDQIQQVVNHGLVPFLVSVLSKADFKTQKEAVWAVTNYTSGGTVEQI 413
Score = 62.1 bits (144), Expect = 2e-09
Identities = 42/144 (29%), Positives = 66/144 (45%)
Frame = +3
Query: 237 ENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNI 416
++PE LA L+ N I ++ G++P LV+ L ++ P + A+ NI
Sbjct: 263 DDPEV-LADTCWAISYLTDGPNERIGMVVKTGVVPQLVKLLGASELPIVT-PALRAIGNI 320
Query: 417 ASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVK 596
+GT QT V+ AGA+ VF LL +P N+ +A W + NI V+ G+V
Sbjct: 321 VTGTDEQTQVVIDAGALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQVVNHGLV- 379
Query: 597 PLLSLIKSDIPIPFLRNVTWVIVN 668
P L + S + W + N
Sbjct: 380 PFLVSVLSKADFKTQKEAVWAVTN 403
>BC053343-1|AAH53343.1| 529|Homo sapiens karyopherin alpha 2 (RAG
cohort 1, importin alpha 1) protein.
Length = 529
Score = 283 bits (694), Expect = 5e-76
Identities = 145/275 (52%), Positives = 185/275 (67%), Gaps = 9/275 (3%)
Frame = +3
Query: 24 RMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNV---PISYSTDEEEIDKNLA 194
R+H FKN GKD EMRRRR EV VELRK K+++ + KRRNV P ++ +E N
Sbjct: 13 RLHRFKNKGKDSTEMRRRRIEVNVELRKAKKDDQMLKRRNVSSFPDDATSPLQENRNNQG 72
Query: 195 TTD--LDELVMNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRA 368
T + +D++V N+ N E QL A Q RKLLS +K PPID +I AG++P V L R
Sbjct: 73 TVNWSVDDIV-KGINSSNVENQLQATQAARKLLSREKQPPIDNIIRAGLIPKFVSFLGRT 131
Query: 369 DNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIG 548
D +QFE+AWALTNIASGTS QT VV GA+P F+ LL SPH ++ +QAVWALGNI G
Sbjct: 132 DCSPIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAG 191
Query: 549 DGPVLRDFVIELGVVKPLLSLI----KSDIPIPFLRNVTWVIVNLCRSKDPPPPLKTIQE 716
DG V RD VI+ G V PLL+L+ S + +LRN+TW + NLCR+K+P PP+ +++
Sbjct: 192 DGSVFRDLVIKYGAVDPLLALLAVPEMSSLACGYLRNLTWTLSNLCRNKNPAPPIDAVEQ 251
Query: 717 ILPALNVLILHNDSSVLVDTVWAIXYLTDGGNEQI 821
ILP L L+ H+D VL DT WAI YLTDG NE+I
Sbjct: 252 ILPTLVRLLHHDDPEVLADTCWAISYLTDGPNERI 286
Score = 67.7 bits (158), Expect = 5e-11
Identities = 48/174 (27%), Positives = 79/174 (45%), Gaps = 1/174 (0%)
Frame = +3
Query: 303 PPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQ 482
PPID + ILP LV+ L D+P + +T WA++ + G + + VV G VP ++
Sbjct: 244 PPIDAV--EQILPTLVRLLHH-DDPEVLADTCWAISYLTDGPNERIGMVVKTGVVPQLVK 300
Query: 483 LLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTWVI 662
LL + + A+ A+GNI+ VI+ G + SL+ + + TW +
Sbjct: 301 LLGASELPIVTPALRAIGNIVTGTDEQTQVVIDAGALAVFPSLLTNP-KTNIQKEATWTM 359
Query: 663 VNLCRSKDPPPPLKTIQEILPALNVLILHNDSSVLVDTVWAIXYLTDGGN-EQI 821
N+ + ++P L ++ D + VWA+ T GG EQI
Sbjct: 360 SNITAGRQDQIQQVVNHGLVPFLVSVLSKADFKTQKEAVWAVTNYTSGGTVEQI 413
Score = 62.1 bits (144), Expect = 2e-09
Identities = 42/144 (29%), Positives = 66/144 (45%)
Frame = +3
Query: 237 ENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNI 416
++PE LA L+ N I ++ G++P LV+ L ++ P + A+ NI
Sbjct: 263 DDPEV-LADTCWAISYLTDGPNERIGMVVKTGVVPQLVKLLGASELPIVT-PALRAIGNI 320
Query: 417 ASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVK 596
+GT QT V+ AGA+ VF LL +P N+ +A W + NI V+ G+V
Sbjct: 321 VTGTDEQTQVVIDAGALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQVVNHGLV- 379
Query: 597 PLLSLIKSDIPIPFLRNVTWVIVN 668
P L + S + W + N
Sbjct: 380 PFLVSVLSKADFKTQKEAVWAVTN 403
>AJ303086-1|CAC83080.1| 529|Homo sapiens karyopherin alpha 2
protein.
Length = 529
Score = 283 bits (694), Expect = 5e-76
Identities = 145/275 (52%), Positives = 185/275 (67%), Gaps = 9/275 (3%)
Frame = +3
Query: 24 RMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNV---PISYSTDEEEIDKNLA 194
R+H FKN GKD EMRRRR EV VELRK K+++ + KRRNV P ++ +E N
Sbjct: 13 RLHRFKNKGKDSTEMRRRRIEVNVELRKAKKDDQMLKRRNVSSFPDDATSPLQENRNNQG 72
Query: 195 TTD--LDELVMNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRA 368
T + +D++V N+ N E QL A Q RKLLS +K PPID +I AG++P V L R
Sbjct: 73 TVNWSVDDIV-KGINSSNVENQLQATQAARKLLSREKQPPIDNIIRAGLIPKFVSFLGRT 131
Query: 369 DNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIG 548
D +QFE+AWALTNIASGTS QT VV GA+P F+ LL SPH ++ +QAVWALGNI G
Sbjct: 132 DCSPIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAG 191
Query: 549 DGPVLRDFVIELGVVKPLLSLI----KSDIPIPFLRNVTWVIVNLCRSKDPPPPLKTIQE 716
DG V RD VI+ G V PLL+L+ S + +LRN+TW + NLCR+K+P PP+ +++
Sbjct: 192 DGSVFRDLVIKYGAVDPLLALLAVPDMSSLACGYLRNLTWTLSNLCRNKNPAPPIDAVEQ 251
Query: 717 ILPALNVLILHNDSSVLVDTVWAIXYLTDGGNEQI 821
ILP L L+ H+D VL DT WAI YLTDG NE+I
Sbjct: 252 ILPTLVRLLHHDDPEVLADTCWAISYLTDGPNERI 286
Score = 67.7 bits (158), Expect = 5e-11
Identities = 48/174 (27%), Positives = 79/174 (45%), Gaps = 1/174 (0%)
Frame = +3
Query: 303 PPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQ 482
PPID + ILP LV+ L D+P + +T WA++ + G + + VV G VP ++
Sbjct: 244 PPIDAV--EQILPTLVRLLHH-DDPEVLADTCWAISYLTDGPNERIGMVVKTGVVPQLVK 300
Query: 483 LLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTWVI 662
LL + + A+ A+GNI+ VI+ G + SL+ + + TW +
Sbjct: 301 LLGASELPIVTPALRAIGNIVTGTDEQTQVVIDAGALAVFPSLLTNP-KTNIQKEATWTM 359
Query: 663 VNLCRSKDPPPPLKTIQEILPALNVLILHNDSSVLVDTVWAIXYLTDGGN-EQI 821
N+ + ++P L ++ D + VWA+ T GG EQI
Sbjct: 360 SNITAGRQDQIQQVVNHGLVPFLVSVLSKADFKTQKEAVWAVTNYTSGGTVEQI 413
Score = 62.1 bits (144), Expect = 2e-09
Identities = 42/144 (29%), Positives = 66/144 (45%)
Frame = +3
Query: 237 ENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNI 416
++PE LA L+ N I ++ G++P LV+ L ++ P + A+ NI
Sbjct: 263 DDPEV-LADTCWAISYLTDGPNERIGMVVKTGVVPQLVKLLGASELPIVT-PALRAIGNI 320
Query: 417 ASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVK 596
+GT QT V+ AGA+ VF LL +P N+ +A W + NI V+ G+V
Sbjct: 321 VTGTDEQTQVVIDAGALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQVVNHGLV- 379
Query: 597 PLLSLIKSDIPIPFLRNVTWVIVN 668
P L + S + W + N
Sbjct: 380 PFLVSVLSKADFKTQKEAVWAVTN 403
>BT006665-1|AAP35311.1| 529|Homo sapiens karyopherin alpha 2 (RAG
cohort 1, importin alpha 1) protein.
Length = 529
Score = 283 bits (693), Expect = 7e-76
Identities = 145/275 (52%), Positives = 185/275 (67%), Gaps = 9/275 (3%)
Frame = +3
Query: 24 RMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNV---PISYSTDEEEIDKNLA 194
R+H FKN GKD EMRRRR EV VELRK K+++ + KRRNV P ++ +E N
Sbjct: 13 RLHRFKNKGKDSTEMRRRRIEVNVELRKAKKDDQMLKRRNVSSFPDDATSPLQENRNNQG 72
Query: 195 TTD--LDELVMNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRA 368
T + +D++V N+ N E QL A Q RKLLS +K PPID +I AG++P V L R
Sbjct: 73 TVNWSVDDIV-KGINSSNVENQLQATQAARKLLSREKQPPIDNIIRAGLIPKFVSFLGRT 131
Query: 369 DNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIG 548
D +QFE+AWALTNIASGTS QT VV GA+P F+ LL SPH ++ +QAVWALGNI G
Sbjct: 132 DCSPIQFESAWALTNIASGTSEQTKVVVDGGAIPAFISLLASPHAHISEQAVWALGNIAG 191
Query: 549 DGPVLRDFVIELGVVKPLLSLI----KSDIPIPFLRNVTWVIVNLCRSKDPPPPLKTIQE 716
DG V RD VI+ G V PLL+L+ S + +LRN+TW + NLCR+K+P PP+ +++
Sbjct: 192 DGSVFRDLVIKYGAVDPLLALLAVPDMSSLACGYLRNLTWTLSNLCRNKNPAPPIDAVEQ 251
Query: 717 ILPALNVLILHNDSSVLVDTVWAIXYLTDGGNEQI 821
ILP L L+ H+D VL DT WAI YLTDG NE+I
Sbjct: 252 ILPTLVRLLHHDDPEVLADTCWAISYLTDGPNERI 286
Score = 67.7 bits (158), Expect = 5e-11
Identities = 48/174 (27%), Positives = 79/174 (45%), Gaps = 1/174 (0%)
Frame = +3
Query: 303 PPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQ 482
PPID + ILP LV+ L D+P + +T WA++ + G + + VV G VP ++
Sbjct: 244 PPIDAV--EQILPTLVRLLHH-DDPEVLADTCWAISYLTDGPNERIGMVVKTGVVPQLVK 300
Query: 483 LLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTWVI 662
LL + + A+ A+GNI+ VI+ G + SL+ + + TW +
Sbjct: 301 LLGASELPIVTPALRAIGNIVTGTDEQTQVVIDAGALAVFPSLLTNP-KTNIQKEATWTM 359
Query: 663 VNLCRSKDPPPPLKTIQEILPALNVLILHNDSSVLVDTVWAIXYLTDGGN-EQI 821
N+ + ++P L ++ D + VWA+ T GG EQI
Sbjct: 360 SNITAGRQDQIQQVVNHGLVPFLVSVLSKADFKTQKEAVWAVTNYTSGGTVEQI 413
Score = 62.1 bits (144), Expect = 2e-09
Identities = 42/144 (29%), Positives = 66/144 (45%)
Frame = +3
Query: 237 ENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNI 416
++PE LA L+ N I ++ G++P LV+ L ++ P + A+ NI
Sbjct: 263 DDPEV-LADTCWAISYLTDGPNERIGMVVKTGVVPQLVKLLGASELPIVT-PALRAIGNI 320
Query: 417 ASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVK 596
+GT QT V+ AGA+ VF LL +P N+ +A W + NI V+ G+V
Sbjct: 321 VTGTDEQTQVVIDAGALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQVVNHGLV- 379
Query: 597 PLLSLIKSDIPIPFLRNVTWVIVN 668
P L + S + W + N
Sbjct: 380 PFLVSVLSKADFKTQKEAVWAVTN 403
>BC005978-1|AAH05978.1| 529|Homo sapiens karyopherin alpha 2 (RAG
cohort 1, importin alpha 1) protein.
Length = 529
Score = 283 bits (693), Expect = 7e-76
Identities = 145/275 (52%), Positives = 185/275 (67%), Gaps = 9/275 (3%)
Frame = +3
Query: 24 RMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNV---PISYSTDEEEIDKNLA 194
R+H FKN GKD EMRRRR EV VELRK K+++ + KRRNV P ++ +E N
Sbjct: 13 RLHRFKNKGKDSTEMRRRRIEVNVELRKAKKDDQMLKRRNVSSFPDDATSPLQENRNNQG 72
Query: 195 TTD--LDELVMNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRA 368
T + +D++V N+ N E QL A Q RKLLS +K PPID +I AG++P V L R
Sbjct: 73 TVNWSVDDIV-KGINSSNVENQLQATQAARKLLSREKQPPIDNIIRAGLIPKFVSFLGRT 131
Query: 369 DNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIG 548
D +QFE+AWALTNIASGTS QT VV GA+P F+ LL SPH ++ +QAVWALGNI G
Sbjct: 132 DCSPIQFESAWALTNIASGTSEQTKVVVDGGAIPAFISLLASPHAHISEQAVWALGNIAG 191
Query: 549 DGPVLRDFVIELGVVKPLLSLI----KSDIPIPFLRNVTWVIVNLCRSKDPPPPLKTIQE 716
DG V RD VI+ G V PLL+L+ S + +LRN+TW + NLCR+K+P PP+ +++
Sbjct: 192 DGSVFRDLVIKYGAVDPLLALLAVPDMSSLACGYLRNLTWTLSNLCRNKNPAPPIDAVEQ 251
Query: 717 ILPALNVLILHNDSSVLVDTVWAIXYLTDGGNEQI 821
ILP L L+ H+D VL DT WAI YLTDG NE+I
Sbjct: 252 ILPTLVRLLHHDDPEVLADTCWAISYLTDGPNERI 286
Score = 67.7 bits (158), Expect = 5e-11
Identities = 48/174 (27%), Positives = 79/174 (45%), Gaps = 1/174 (0%)
Frame = +3
Query: 303 PPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQ 482
PPID + ILP LV+ L D+P + +T WA++ + G + + VV G VP ++
Sbjct: 244 PPIDAV--EQILPTLVRLLHH-DDPEVLADTCWAISYLTDGPNERIGMVVKTGVVPQLVK 300
Query: 483 LLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTWVI 662
LL + + A+ A+GNI+ VI+ G + SL+ + + TW +
Sbjct: 301 LLGASELPIVTPALRAIGNIVTGTDEQTQVVIDAGALAVFPSLLTNP-KTNIQKEATWTM 359
Query: 663 VNLCRSKDPPPPLKTIQEILPALNVLILHNDSSVLVDTVWAIXYLTDGGN-EQI 821
N+ + ++P L ++ D + VWA+ T GG EQI
Sbjct: 360 SNITAGRQDQIQQVVNHGLVPFLVSVLSKADFKTQKEAVWAVTNYTSGGTVEQI 413
Score = 62.1 bits (144), Expect = 2e-09
Identities = 42/144 (29%), Positives = 66/144 (45%)
Frame = +3
Query: 237 ENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNI 416
++PE LA L+ N I ++ G++P LV+ L ++ P + A+ NI
Sbjct: 263 DDPEV-LADTCWAISYLTDGPNERIGMVVKTGVVPQLVKLLGASELPIVT-PALRAIGNI 320
Query: 417 ASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVK 596
+GT QT V+ AGA+ VF LL +P N+ +A W + NI V+ G+V
Sbjct: 321 VTGTDEQTQVVIDAGALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQVVNHGLV- 379
Query: 597 PLLSLIKSDIPIPFLRNVTWVIVN 668
P L + S + W + N
Sbjct: 380 PFLVSVLSKADFKTQKEAVWAVTN 403
>BC067848-1|AAH67848.1| 529|Homo sapiens karyopherin alpha 2 (RAG
cohort 1, importin alpha 1) protein.
Length = 529
Score = 277 bits (679), Expect = 4e-74
Identities = 143/275 (52%), Positives = 183/275 (66%), Gaps = 9/275 (3%)
Frame = +3
Query: 24 RMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNV---PISYSTDEEEIDKNLA 194
R+H FKN GKD EMRRRR EV VELRK K+++ + KRRNV P ++ +E N
Sbjct: 13 RLHRFKNKGKDSTEMRRRRIEVNVELRKAKKDDQMLKRRNVSSFPDDATSPLQENRNNQG 72
Query: 195 TTD--LDELVMNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRA 368
T + +D++V N+ N E QL A Q RKLLS +K PPID +I AG++P V L R
Sbjct: 73 TVNWSVDDIV-KGINSSNVENQLQATQAARKLLSREKQPPIDNIIRAGLIPKFVSFLGRT 131
Query: 369 DNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIG 548
D +QFE+AWALTNIASGTS QT VV GA+ F+ LL SPH ++ +Q VWALGNI G
Sbjct: 132 DCSPIQFESAWALTNIASGTSEQTKAVVDGGAIRAFISLLASPHAHISEQDVWALGNIAG 191
Query: 549 DGPVLRDFVIELGVVKPLLSLI----KSDIPIPFLRNVTWVIVNLCRSKDPPPPLKTIQE 716
DG V RD VI+ G V PLL+L+ S + +LRN+TW + NLCR+K+P PP+ +++
Sbjct: 192 DGSVFRDLVIKYGAVDPLLALLAVPDMSSLACGYLRNLTWTLSNLCRNKNPAPPIDAVEQ 251
Query: 717 ILPALNVLILHNDSSVLVDTVWAIXYLTDGGNEQI 821
ILP L L+ H+D VL DT WAI YLTDG NE+I
Sbjct: 252 ILPTLVRLLHHDDPEVLADTCWAISYLTDGPNERI 286
Score = 67.7 bits (158), Expect = 5e-11
Identities = 48/174 (27%), Positives = 79/174 (45%), Gaps = 1/174 (0%)
Frame = +3
Query: 303 PPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQ 482
PPID + ILP LV+ L D+P + +T WA++ + G + + VV G VP ++
Sbjct: 244 PPIDAV--EQILPTLVRLLHH-DDPEVLADTCWAISYLTDGPNERIGMVVKTGVVPQLVK 300
Query: 483 LLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTWVI 662
LL + + A+ A+GNI+ VI+ G + SL+ + + TW +
Sbjct: 301 LLGASELPIVTPALRAIGNIVTGTDEQTQVVIDAGALAVFPSLLTNP-KTNIQKEATWTM 359
Query: 663 VNLCRSKDPPPPLKTIQEILPALNVLILHNDSSVLVDTVWAIXYLTDGGN-EQI 821
N+ + ++P L ++ D + VWA+ T GG EQI
Sbjct: 360 SNITAGRQDQIQQVVNHGLVPFLVSVLSKADFKTQKEAVWAVTNYTSGGTVEQI 413
Score = 62.1 bits (144), Expect = 2e-09
Identities = 42/144 (29%), Positives = 66/144 (45%)
Frame = +3
Query: 237 ENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNI 416
++PE LA L+ N I ++ G++P LV+ L ++ P + A+ NI
Sbjct: 263 DDPEV-LADTCWAISYLTDGPNERIGMVVKTGVVPQLVKLLGASELPIVT-PALRAIGNI 320
Query: 417 ASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVK 596
+GT QT V+ AGA+ VF LL +P N+ +A W + NI V+ G+V
Sbjct: 321 VTGTDEQTQVVIDAGALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQVVNHGLV- 379
Query: 597 PLLSLIKSDIPIPFLRNVTWVIVN 668
P L + S + W + N
Sbjct: 380 PFLVSVLSKADFKTQKEAVWAVTN 403
>CR456743-1|CAG33024.1| 538|Homo sapiens KPNA1 protein.
Length = 538
Score = 237 bits (581), Expect = 3e-62
Identities = 124/280 (44%), Positives = 170/280 (60%), Gaps = 14/280 (5%)
Frame = +3
Query: 24 RMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPISYSTDEEEI--DKNLAT 197
R+ +KN + DEMRRRR E ++LRK KREE L KRRNV + EEE+ D
Sbjct: 10 RLKSYKNKSLNPDEMRRRREEEGLQLRKQKREEQLFKRRNVATAEEETEEEVMSDGGFHE 69
Query: 198 TDLDELVMNAAN-----------AENPEAQLAAVQQCRKLLSCDKNPPIDELIAA-GILP 341
++ + M +++PE QL+A Q+ RKLLS + NPPIDE+I+ G++
Sbjct: 70 AQINNMEMAPGGVITSDMIEMIFSKSPEQQLSATQKFRKLLSKEPNPPIDEVISTPGVVA 129
Query: 342 ILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQA 521
V+ L R +N LQFE+AW LTNIASG S QT V+ AGAVP+F++LL S E+V +QA
Sbjct: 130 RFVEFLKRKENCTLQFESAWVLTNIASGNSLQTRIVIQAGAVPIFIELLSSEFEDVQEQA 189
Query: 522 VWALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTWVIVNLCRSKDPPPPL 701
VWALGNI GD + RD+V++ ++ PLL L + RN W + NLCR K PPP
Sbjct: 190 VWALGNIAGDSTMCRDYVLDCNILPPLLQLFSKQNRLTMTRNAVWALSNLCRGKSPPPEF 249
Query: 702 KTIQEILPALNVLILHNDSSVLVDTVWAIXYLTDGGNEQI 821
+ L L+ L+ +D+ VL D WA+ YL+DG N++I
Sbjct: 250 AKVSPCLNVLSWLLFVSDTDVLADACWALSYLSDGPNDKI 289
Score = 57.2 bits (132), Expect = 7e-08
Identities = 44/176 (25%), Positives = 74/176 (42%), Gaps = 1/176 (0%)
Frame = +3
Query: 297 KNPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVF 476
K+PP + + L +L L +D L + WAL+ ++ G + + V+ AG
Sbjct: 243 KSPPPEFAKVSPCLNVLSWLLFVSDTDVLA-DACWALSYLSDGPNDKIQAVIDAGVCRRL 301
Query: 477 LQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTW 656
++LLM V A+ A+GNI+ + ++ ++ LL L+ S + W
Sbjct: 302 VELLMHNDYKVVSPALRAVGNIVTGDDIQTQVILNCSALQSLLHLLSSP-KESIKKEACW 360
Query: 657 VIVNLCRSKDPPPPLKTIQEILPALNVLILHNDSSVLVDTVWAIXYLTDGGN-EQI 821
I N+ I PAL ++ + + WAI T GG+ EQI
Sbjct: 361 TISNITAGNRAQIQTVIDANIFPALISILQTAEFRTRKEAAWAITNATSGGSAEQI 416
Score = 52.8 bits (121), Expect = 1e-06
Identities = 27/100 (27%), Positives = 49/100 (49%), Gaps = 1/100 (1%)
Frame = +3
Query: 318 LIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSP 497
++ L L+ LS + +++ E W ++NI +G AQ V+ A P + +L +
Sbjct: 334 ILNCSALQSLLHLLS-SPKESIKKEACWTISNITAGNRAQIQTVIDANIFPALISILQTA 392
Query: 498 HENVCDQAVWALGNIIGDGPVLR-DFVIELGVVKPLLSLI 614
+A WA+ N G + +++ELG +KPL L+
Sbjct: 393 EFRTRKEAAWAITNATSGGSAEQIKYLVELGCIKPLCDLL 432
Score = 39.5 bits (88), Expect = 0.014
Identities = 27/80 (33%), Positives = 38/80 (47%), Gaps = 1/80 (1%)
Frame = +3
Query: 309 IDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNK-VVHAGAVPVFLQL 485
I +I A I P L+ L A+ + E AWA+TN SG SA+ K +V G + L
Sbjct: 373 IQTVIDANIFPALISILQTAEFRTRK-EAAWAITNATSGGSAEQIKYLVELGCIKPLCDL 431
Query: 486 LMSPHENVCDQAVWALGNII 545
L + A+ L NI+
Sbjct: 432 LTVMDSKIVQVALNGLENIL 451
>BT006959-1|AAP35605.1| 538|Homo sapiens karyopherin alpha 1
(importin alpha 5) protein.
Length = 538
Score = 237 bits (581), Expect = 3e-62
Identities = 124/280 (44%), Positives = 170/280 (60%), Gaps = 14/280 (5%)
Frame = +3
Query: 24 RMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPISYSTDEEEI--DKNLAT 197
R+ +KN + DEMRRRR E ++LRK KREE L KRRNV + EEE+ D
Sbjct: 10 RLKSYKNKSLNPDEMRRRREEEGLQLRKQKREEQLFKRRNVATAEEETEEEVMSDGGFHE 69
Query: 198 TDLDELVMNAAN-----------AENPEAQLAAVQQCRKLLSCDKNPPIDELIAA-GILP 341
++ + M +++PE QL+A Q+ RKLLS + NPPIDE+I+ G++
Sbjct: 70 AQINNMEMAPGGVITSDMIEMIFSKSPEQQLSATQKFRKLLSKEPNPPIDEVISTPGVVA 129
Query: 342 ILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQA 521
V+ L R +N LQFE+AW LTNIASG S QT V+ AGAVP+F++LL S E+V +QA
Sbjct: 130 RFVEFLKRKENCTLQFESAWVLTNIASGNSLQTRIVIQAGAVPIFIELLSSEFEDVQEQA 189
Query: 522 VWALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTWVIVNLCRSKDPPPPL 701
VWALGNI GD + RD+V++ ++ PLL L + RN W + NLCR K PPP
Sbjct: 190 VWALGNIAGDSTMCRDYVLDCNILPPLLQLFSKQNRLTMTRNAVWALSNLCRGKSPPPEF 249
Query: 702 KTIQEILPALNVLILHNDSSVLVDTVWAIXYLTDGGNEQI 821
+ L L+ L+ +D+ VL D WA+ YL+DG N++I
Sbjct: 250 AKVSPCLNVLSWLLFVSDTDVLADACWALSYLSDGPNDKI 289
Score = 57.2 bits (132), Expect = 7e-08
Identities = 44/176 (25%), Positives = 74/176 (42%), Gaps = 1/176 (0%)
Frame = +3
Query: 297 KNPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVF 476
K+PP + + L +L L +D L + WAL+ ++ G + + V+ AG
Sbjct: 243 KSPPPEFAKVSPCLNVLSWLLFVSDTDVLA-DACWALSYLSDGPNDKIQAVIDAGVCRRL 301
Query: 477 LQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTW 656
++LLM V A+ A+GNI+ + ++ ++ LL L+ S + W
Sbjct: 302 VELLMHNDYKVVSPALRAVGNIVTGDDIQTQVILNCSALQSLLHLLSSP-KESIKKEACW 360
Query: 657 VIVNLCRSKDPPPPLKTIQEILPALNVLILHNDSSVLVDTVWAIXYLTDGGN-EQI 821
I N+ I PAL ++ + + WAI T GG+ EQI
Sbjct: 361 TISNITAGNRAQIQTVIDANIFPALISILQTAEFRTRKEAAWAITNATSGGSAEQI 416
Score = 52.8 bits (121), Expect = 1e-06
Identities = 27/100 (27%), Positives = 49/100 (49%), Gaps = 1/100 (1%)
Frame = +3
Query: 318 LIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSP 497
++ L L+ LS + +++ E W ++NI +G AQ V+ A P + +L +
Sbjct: 334 ILNCSALQSLLHLLS-SPKESIKKEACWTISNITAGNRAQIQTVIDANIFPALISILQTA 392
Query: 498 HENVCDQAVWALGNIIGDGPVLR-DFVIELGVVKPLLSLI 614
+A WA+ N G + +++ELG +KPL L+
Sbjct: 393 EFRTRKEAAWAITNATSGGSAEQIKYLVELGCIKPLCDLL 432
Score = 39.5 bits (88), Expect = 0.014
Identities = 27/80 (33%), Positives = 38/80 (47%), Gaps = 1/80 (1%)
Frame = +3
Query: 309 IDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNK-VVHAGAVPVFLQL 485
I +I A I P L+ L A+ + E AWA+TN SG SA+ K +V G + L
Sbjct: 373 IQTVIDANIFPALISILQTAEFRTRK-EAAWAITNATSGGSAEQIKYLVELGCIKPLCDL 431
Query: 486 LMSPHENVCDQAVWALGNII 545
L + A+ L NI+
Sbjct: 432 LTVMDSKIVQVALNGLENIL 451
>BC090864-1|AAH90864.1| 538|Homo sapiens karyopherin alpha 1
(importin alpha 5) protein.
Length = 538
Score = 237 bits (581), Expect = 3e-62
Identities = 124/280 (44%), Positives = 170/280 (60%), Gaps = 14/280 (5%)
Frame = +3
Query: 24 RMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPISYSTDEEEI--DKNLAT 197
R+ +KN + DEMRRRR E ++LRK KREE L KRRNV + EEE+ D
Sbjct: 10 RLKSYKNKSLNPDEMRRRREEEGLQLRKQKREEQLFKRRNVATAEEETEEEVMSDGGFHE 69
Query: 198 TDLDELVMNAAN-----------AENPEAQLAAVQQCRKLLSCDKNPPIDELIAA-GILP 341
++ + M +++PE QL+A Q+ RKLLS + NPPIDE+I+ G++
Sbjct: 70 AQINNMEMAPGGVITSDMIEMIFSKSPEQQLSATQKFRKLLSKEPNPPIDEVISTPGVVA 129
Query: 342 ILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQA 521
V+ L R +N LQFE+AW LTNIASG S QT V+ AGAVP+F++LL S E+V +QA
Sbjct: 130 RFVEFLKRKENCTLQFESAWVLTNIASGNSLQTRIVIQAGAVPIFIELLSSEFEDVQEQA 189
Query: 522 VWALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTWVIVNLCRSKDPPPPL 701
VWALGNI GD + RD+V++ ++ PLL L + RN W + NLCR K PPP
Sbjct: 190 VWALGNIAGDSTMYRDYVLDCNILPPLLQLFSKQNRLTMTRNAVWALSNLCRGKSPPPEF 249
Query: 702 KTIQEILPALNVLILHNDSSVLVDTVWAIXYLTDGGNEQI 821
+ L L+ L+ +D+ VL D WA+ YL+DG N++I
Sbjct: 250 AKVSPCLNVLSWLLFVSDTDVLADACWALSYLSDGPNDKI 289
Score = 57.2 bits (132), Expect = 7e-08
Identities = 44/176 (25%), Positives = 74/176 (42%), Gaps = 1/176 (0%)
Frame = +3
Query: 297 KNPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVF 476
K+PP + + L +L L +D L + WAL+ ++ G + + V+ AG
Sbjct: 243 KSPPPEFAKVSPCLNVLSWLLFVSDTDVLA-DACWALSYLSDGPNDKIQAVIDAGVCRRL 301
Query: 477 LQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTW 656
++LLM V A+ A+GNI+ + ++ ++ LL L+ S + W
Sbjct: 302 VELLMHNDYKVVSPALRAVGNIVTGDDIQTQVILNCSALQSLLHLLSSP-KESIKKEACW 360
Query: 657 VIVNLCRSKDPPPPLKTIQEILPALNVLILHNDSSVLVDTVWAIXYLTDGGN-EQI 821
I N+ I PAL ++ + + WAI T GG+ EQI
Sbjct: 361 TISNITAGNRAQIQTVIDANIFPALISILQTAEFRTRKEAAWAITNATSGGSAEQI 416
Score = 52.8 bits (121), Expect = 1e-06
Identities = 27/100 (27%), Positives = 49/100 (49%), Gaps = 1/100 (1%)
Frame = +3
Query: 318 LIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSP 497
++ L L+ LS + +++ E W ++NI +G AQ V+ A P + +L +
Sbjct: 334 ILNCSALQSLLHLLS-SPKESIKKEACWTISNITAGNRAQIQTVIDANIFPALISILQTA 392
Query: 498 HENVCDQAVWALGNIIGDGPVLR-DFVIELGVVKPLLSLI 614
+A WA+ N G + +++ELG +KPL L+
Sbjct: 393 EFRTRKEAAWAITNATSGGSAEQIKYLVELGCIKPLCDLL 432
Score = 39.5 bits (88), Expect = 0.014
Identities = 27/80 (33%), Positives = 38/80 (47%), Gaps = 1/80 (1%)
Frame = +3
Query: 309 IDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNK-VVHAGAVPVFLQL 485
I +I A I P L+ L A+ + E AWA+TN SG SA+ K +V G + L
Sbjct: 373 IQTVIDANIFPALISILQTAEFRTRK-EAAWAITNATSGGSAEQIKYLVELGCIKPLCDL 431
Query: 486 LMSPHENVCDQAVWALGNII 545
L + A+ L NI+
Sbjct: 432 LTVMDSKIVQVALNGLENIL 451
>BC003009-1|AAH03009.1| 538|Homo sapiens karyopherin alpha 1
(importin alpha 5) protein.
Length = 538
Score = 237 bits (581), Expect = 3e-62
Identities = 124/280 (44%), Positives = 170/280 (60%), Gaps = 14/280 (5%)
Frame = +3
Query: 24 RMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPISYSTDEEEI--DKNLAT 197
R+ +KN + DEMRRRR E ++LRK KREE L KRRNV + EEE+ D
Sbjct: 10 RLKSYKNKSLNPDEMRRRREEEGLQLRKQKREEQLFKRRNVATAEEETEEEVMSDGGFHE 69
Query: 198 TDLDELVMNAAN-----------AENPEAQLAAVQQCRKLLSCDKNPPIDELIAA-GILP 341
++ + M +++PE QL+A Q+ RKLLS + NPPIDE+I+ G++
Sbjct: 70 AQINNMEMAPGGVITSDMIEMIFSKSPEQQLSATQKFRKLLSKEPNPPIDEVISTPGVVA 129
Query: 342 ILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQA 521
V+ L R +N LQFE+AW LTNIASG S QT V+ AGAVP+F++LL S E+V +QA
Sbjct: 130 RFVEFLKRKENCTLQFESAWVLTNIASGNSLQTRIVIQAGAVPIFIELLSSEFEDVQEQA 189
Query: 522 VWALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTWVIVNLCRSKDPPPPL 701
VWALGNI GD + RD+V++ ++ PLL L + RN W + NLCR K PPP
Sbjct: 190 VWALGNIAGDSTMCRDYVLDCNILPPLLQLFSKQNRLTMTRNAVWALSNLCRGKSPPPEF 249
Query: 702 KTIQEILPALNVLILHNDSSVLVDTVWAIXYLTDGGNEQI 821
+ L L+ L+ +D+ VL D WA+ YL+DG N++I
Sbjct: 250 AKVSPCLNVLSWLLFVSDTDVLADACWALSYLSDGPNDKI 289
Score = 57.2 bits (132), Expect = 7e-08
Identities = 44/176 (25%), Positives = 74/176 (42%), Gaps = 1/176 (0%)
Frame = +3
Query: 297 KNPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVF 476
K+PP + + L +L L +D L + WAL+ ++ G + + V+ AG
Sbjct: 243 KSPPPEFAKVSPCLNVLSWLLFVSDTDVLA-DACWALSYLSDGPNDKIQAVIDAGVCRRL 301
Query: 477 LQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTW 656
++LLM V A+ A+GNI+ + ++ ++ LL L+ S + W
Sbjct: 302 VELLMHNDYKVVSPALRAVGNIVTGDDIQTQVILNCSALQSLLHLLSSP-KESIKKEACW 360
Query: 657 VIVNLCRSKDPPPPLKTIQEILPALNVLILHNDSSVLVDTVWAIXYLTDGGN-EQI 821
I N+ I PAL ++ + + WAI T GG+ EQI
Sbjct: 361 TISNITAGNRAQIQTVIDANIFPALISILQTAEFRTRKEAAWAITNATSGGSAEQI 416
Score = 52.8 bits (121), Expect = 1e-06
Identities = 27/100 (27%), Positives = 49/100 (49%), Gaps = 1/100 (1%)
Frame = +3
Query: 318 LIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSP 497
++ L L+ LS + +++ E W ++NI +G AQ V+ A P + +L +
Sbjct: 334 ILNCSALQSLLHLLS-SPKESIKKEACWTISNITAGNRAQIQTVIDANIFPALISILQTA 392
Query: 498 HENVCDQAVWALGNIIGDGPVLR-DFVIELGVVKPLLSLI 614
+A WA+ N G + +++ELG +KPL L+
Sbjct: 393 EFRTRKEAAWAITNATSGGSAEQIKYLVELGCIKPLCDLL 432
Score = 39.5 bits (88), Expect = 0.014
Identities = 27/80 (33%), Positives = 38/80 (47%), Gaps = 1/80 (1%)
Frame = +3
Query: 309 IDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNK-VVHAGAVPVFLQL 485
I +I A I P L+ L A+ + E AWA+TN SG SA+ K +V G + L
Sbjct: 373 IQTVIDANIFPALISILQTAEFRTRK-EAAWAITNATSGGSAEQIKYLVELGCIKPLCDL 431
Query: 486 LMSPHENVCDQAVWALGNII 545
L + A+ L NI+
Sbjct: 432 LTVMDSKIVQVALNGLENIL 451
>BC002374-1|AAH02374.1| 538|Homo sapiens karyopherin alpha 1
(importin alpha 5) protein.
Length = 538
Score = 237 bits (581), Expect = 3e-62
Identities = 124/280 (44%), Positives = 170/280 (60%), Gaps = 14/280 (5%)
Frame = +3
Query: 24 RMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPISYSTDEEEI--DKNLAT 197
R+ +KN + DEMRRRR E ++LRK KREE L KRRNV + EEE+ D
Sbjct: 10 RLKSYKNKSLNPDEMRRRREEEGLQLRKQKREEQLFKRRNVATAEEETEEEVMSDGGFHE 69
Query: 198 TDLDELVMNAAN-----------AENPEAQLAAVQQCRKLLSCDKNPPIDELIAA-GILP 341
++ + M +++PE QL+A Q+ RKLLS + NPPIDE+I+ G++
Sbjct: 70 AQINNMEMAPGGVITSDMIEMIFSKSPEQQLSATQKFRKLLSKEPNPPIDEVISTPGVVA 129
Query: 342 ILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQA 521
V+ L R +N LQFE+AW LTNIASG S QT V+ AGAVP+F++LL S E+V +QA
Sbjct: 130 RFVEFLKRKENCTLQFESAWVLTNIASGNSLQTRIVIQAGAVPIFIELLSSEFEDVQEQA 189
Query: 522 VWALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTWVIVNLCRSKDPPPPL 701
VWALGNI GD + RD+V++ ++ PLL L + RN W + NLCR K PPP
Sbjct: 190 VWALGNIAGDSTMCRDYVLDCNILPPLLQLFSKQNRLTMTRNAVWALSNLCRGKSPPPEF 249
Query: 702 KTIQEILPALNVLILHNDSSVLVDTVWAIXYLTDGGNEQI 821
+ L L+ L+ +D+ VL D WA+ YL+DG N++I
Sbjct: 250 AKVSPCLNVLSWLLFVSDTDVLADACWALSYLSDGPNDKI 289
Score = 57.2 bits (132), Expect = 7e-08
Identities = 44/176 (25%), Positives = 74/176 (42%), Gaps = 1/176 (0%)
Frame = +3
Query: 297 KNPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVF 476
K+PP + + L +L L +D L + WAL+ ++ G + + V+ AG
Sbjct: 243 KSPPPEFAKVSPCLNVLSWLLFVSDTDVLA-DACWALSYLSDGPNDKIQAVIDAGVCRRL 301
Query: 477 LQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTW 656
++LLM V A+ A+GNI+ + ++ ++ LL L+ S + W
Sbjct: 302 VELLMHNDYKVVSPALRAVGNIVTGDDIQTQVILNCSALQSLLHLLSSP-KESIKKEACW 360
Query: 657 VIVNLCRSKDPPPPLKTIQEILPALNVLILHNDSSVLVDTVWAIXYLTDGGN-EQI 821
I N+ I PAL ++ + + WAI T GG+ EQI
Sbjct: 361 TISNITAGNRAQIQTVIDANIFPALISILQTAEFRTRKEAAWAITNATSGGSAEQI 416
Score = 52.8 bits (121), Expect = 1e-06
Identities = 27/100 (27%), Positives = 49/100 (49%), Gaps = 1/100 (1%)
Frame = +3
Query: 318 LIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSP 497
++ L L+ LS + +++ E W ++NI +G AQ V+ A P + +L +
Sbjct: 334 ILNCSALQSLLHLLS-SPKESIKKEACWTISNITAGNRAQIQTVIDANIFPALISILQTA 392
Query: 498 HENVCDQAVWALGNIIGDGPVLR-DFVIELGVVKPLLSLI 614
+A WA+ N G + +++ELG +KPL L+
Sbjct: 393 EFRTRKEAAWAITNATSGGSAEQIKYLVELGCIKPLCDLL 432
Score = 39.5 bits (88), Expect = 0.014
Identities = 27/80 (33%), Positives = 38/80 (47%), Gaps = 1/80 (1%)
Frame = +3
Query: 309 IDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNK-VVHAGAVPVFLQL 485
I +I A I P L+ L A+ + E AWA+TN SG SA+ K +V G + L
Sbjct: 373 IQTVIDANIFPALISILQTAEFRTRK-EAAWAITNATSGGSAEQIKYLVELGCIKPLCDL 431
Query: 486 LMSPHENVCDQAVWALGNII 545
L + A+ L NI+
Sbjct: 432 LTVMDSKIVQVALNGLENIL 451
>BT009843-1|AAP88845.1| 536|Homo sapiens karyopherin alpha 6
(importin alpha 7) protein.
Length = 536
Score = 236 bits (577), Expect = 8e-62
Identities = 122/275 (44%), Positives = 173/275 (62%), Gaps = 9/275 (3%)
Frame = +3
Query: 24 RMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPI----SYSTDEEEIDKNL 191
RM +KN + +EMRRRR E ++LRK KRE+ L KRRNV + + D +D +
Sbjct: 13 RMKSYKNNALNPEEMRRRREEEGIQLRKQKREQQLFKRRNVELINEEAAMFDSLLMDSYV 72
Query: 192 ATTDLDELV----MNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELI-AAGILPILVQC 356
++T + ++ + +++ + QLA Q+ RKLLS + +PPIDE+I ++ V+
Sbjct: 73 SSTTGESVITREMVEMLFSDDSDLQLATTQKFRKLLSKEPSPPIDEVINTPRVVDRFVEF 132
Query: 357 LSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALG 536
L R +N LQFE AWALTNIASGTS QT V+ AGAVP+F++LL S E+V +QAVWALG
Sbjct: 133 LKRNENCTLQFEAAWALTNIASGTSQQTKIVIEAGAVPIFIELLNSDFEDVQEQAVWALG 192
Query: 537 NIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTWVIVNLCRSKDPPPPLKTIQE 716
NI GD V RD+V+ ++ PLL+L+ + RN W + NLCR K+PPP +
Sbjct: 193 NIAGDSSVCRDYVLNCSILNPLLTLLTKSTRLTMTRNAVWALSNLCRGKNPPPEFAKVSP 252
Query: 717 ILPALNVLILHNDSSVLVDTVWAIXYLTDGGNEQI 821
LP L+ L+ +DS +L D WA+ YL+DG NE+I
Sbjct: 253 CLPVLSRLLFSSDSDLLADACWALSYLSDGPNEKI 287
Score = 61.7 bits (143), Expect = 3e-09
Identities = 46/177 (25%), Positives = 76/177 (42%), Gaps = 2/177 (1%)
Frame = +3
Query: 297 KNPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVF 476
KNPP + + LP+L + L +D+ L + WAL+ ++ G + + V+ +G
Sbjct: 241 KNPPPEFAKVSPCLPVLSRLLFSSDSDLLA-DACWALSYLSDGPNEKIQAVIDSGVCRRL 299
Query: 477 LQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPFLR-NVT 653
++LLM V A+ A+GNI+ + ++ + LL L+ S P +R
Sbjct: 300 VELLMHNDYKVASPALRAVGNIVTGDDIQTQVILNCSALPCLLHLLSS--PKESIRKEAC 357
Query: 654 WVIVNLCRSKDPPPPLKTIQEILPALNVLILHNDSSVLVDTVWAIXYLTDGGN-EQI 821
W I N+ I P L ++ + + WAI T GG EQI
Sbjct: 358 WTISNITAGNRAQIQAVIDANIFPVLIEILQKAEFRTRKEAAWAITNATSGGTPEQI 414
Score = 53.6 bits (123), Expect = 8e-07
Identities = 40/139 (28%), Positives = 60/139 (43%), Gaps = 4/139 (2%)
Frame = +3
Query: 285 LSCDKNPPIDELIAAGILPILVQCLSRAD----NPALQFETAWALTNIASGTSAQTNKVV 452
LS N I +I +G+ LV+ L D +PAL+ A+ NI +G QT ++
Sbjct: 279 LSDGPNEKIQAVIDSGVCRRLVELLMHNDYKVASPALR-----AVGNIVTGDDIQTQVIL 333
Query: 453 HAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPI 632
+ A+P L LL SP E++ +A W + NI VI+ + P+L I
Sbjct: 334 NCSALPCLLHLLSSPKESIRKEACWTISNITAGNRAQIQAVIDANIF-PVLIEILQKAEF 392
Query: 633 PFLRNVTWVIVNLCRSKDP 689
+ W I N P
Sbjct: 393 RTRKEAAWAITNATSGGTP 411
>BC020520-1|AAH20520.1| 536|Homo sapiens karyopherin alpha 6
(importin alpha 7) protein.
Length = 536
Score = 236 bits (577), Expect = 8e-62
Identities = 122/275 (44%), Positives = 173/275 (62%), Gaps = 9/275 (3%)
Frame = +3
Query: 24 RMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPI----SYSTDEEEIDKNL 191
RM +KN + +EMRRRR E ++LRK KRE+ L KRRNV + + D +D +
Sbjct: 13 RMKSYKNNALNPEEMRRRREEEGIQLRKQKREQQLFKRRNVELINEEAAMFDSLLMDSYV 72
Query: 192 ATTDLDELV----MNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELI-AAGILPILVQC 356
++T + ++ + +++ + QLA Q+ RKLLS + +PPIDE+I ++ V+
Sbjct: 73 SSTTGESVITREMVEMLFSDDSDLQLATTQKFRKLLSKEPSPPIDEVINTPRVVDRFVEF 132
Query: 357 LSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALG 536
L R +N LQFE AWALTNIASGTS QT V+ AGAVP+F++LL S E+V +QAVWALG
Sbjct: 133 LKRNENCTLQFEAAWALTNIASGTSQQTKIVIEAGAVPIFIELLNSDFEDVQEQAVWALG 192
Query: 537 NIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTWVIVNLCRSKDPPPPLKTIQE 716
NI GD V RD+V+ ++ PLL+L+ + RN W + NLCR K+PPP +
Sbjct: 193 NIAGDSSVCRDYVLNCSILNPLLTLLTKSTRLTMTRNAVWALSNLCRGKNPPPEFAKVSP 252
Query: 717 ILPALNVLILHNDSSVLVDTVWAIXYLTDGGNEQI 821
LP L+ L+ +DS +L D WA+ YL+DG NE+I
Sbjct: 253 CLPVLSRLLFSSDSDLLADACWALSYLSDGPNEKI 287
Score = 61.7 bits (143), Expect = 3e-09
Identities = 46/177 (25%), Positives = 76/177 (42%), Gaps = 2/177 (1%)
Frame = +3
Query: 297 KNPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVF 476
KNPP + + LP+L + L +D+ L + WAL+ ++ G + + V+ +G
Sbjct: 241 KNPPPEFAKVSPCLPVLSRLLFSSDSDLLA-DACWALSYLSDGPNEKIQAVIDSGVCRRL 299
Query: 477 LQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPFLR-NVT 653
++LLM V A+ A+GNI+ + ++ + LL L+ S P +R
Sbjct: 300 VELLMHNDYKVASPALRAVGNIVTGDDIQTQVILNCSALPCLLHLLSS--PKESIRKEAC 357
Query: 654 WVIVNLCRSKDPPPPLKTIQEILPALNVLILHNDSSVLVDTVWAIXYLTDGGN-EQI 821
W I N+ I P L ++ + + WAI T GG EQI
Sbjct: 358 WTISNITAGNRAQIQAVIDANIFPVLIEILQKAEFRTRKEAAWAITNATSGGTPEQI 414
Score = 53.6 bits (123), Expect = 8e-07
Identities = 40/139 (28%), Positives = 60/139 (43%), Gaps = 4/139 (2%)
Frame = +3
Query: 285 LSCDKNPPIDELIAAGILPILVQCLSRAD----NPALQFETAWALTNIASGTSAQTNKVV 452
LS N I +I +G+ LV+ L D +PAL+ A+ NI +G QT ++
Sbjct: 279 LSDGPNEKIQAVIDSGVCRRLVELLMHNDYKVASPALR-----AVGNIVTGDDIQTQVIL 333
Query: 453 HAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPI 632
+ A+P L LL SP E++ +A W + NI VI+ + P+L I
Sbjct: 334 NCSALPCLLHLLSSPKESIRKEACWTISNITAGNRAQIQAVIDANIF-PVLIEILQKAEF 392
Query: 633 PFLRNVTWVIVNLCRSKDP 689
+ W I N P
Sbjct: 393 RTRKEAAWAITNATSGGTP 411
>AL445248-5|CAH71948.1| 536|Homo sapiens karyopherin alpha 6
(importin alpha 7) protein.
Length = 536
Score = 236 bits (577), Expect = 8e-62
Identities = 122/275 (44%), Positives = 173/275 (62%), Gaps = 9/275 (3%)
Frame = +3
Query: 24 RMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPI----SYSTDEEEIDKNL 191
RM +KN + +EMRRRR E ++LRK KRE+ L KRRNV + + D +D +
Sbjct: 13 RMKSYKNNALNPEEMRRRREEEGIQLRKQKREQQLFKRRNVELINEEAAMFDSLLMDSYV 72
Query: 192 ATTDLDELV----MNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELI-AAGILPILVQC 356
++T + ++ + +++ + QLA Q+ RKLLS + +PPIDE+I ++ V+
Sbjct: 73 SSTTGESVITREMVEMLFSDDSDLQLATTQKFRKLLSKEPSPPIDEVINTPRVVDRFVEF 132
Query: 357 LSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALG 536
L R +N LQFE AWALTNIASGTS QT V+ AGAVP+F++LL S E+V +QAVWALG
Sbjct: 133 LKRNENCTLQFEAAWALTNIASGTSQQTKIVIEAGAVPIFIELLNSDFEDVQEQAVWALG 192
Query: 537 NIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTWVIVNLCRSKDPPPPLKTIQE 716
NI GD V RD+V+ ++ PLL+L+ + RN W + NLCR K+PPP +
Sbjct: 193 NIAGDSSVCRDYVLNCSILNPLLTLLTKSTRLTMTRNAVWALSNLCRGKNPPPEFAKVSP 252
Query: 717 ILPALNVLILHNDSSVLVDTVWAIXYLTDGGNEQI 821
LP L+ L+ +DS +L D WA+ YL+DG NE+I
Sbjct: 253 CLPVLSRLLFSSDSDLLADACWALSYLSDGPNEKI 287
Score = 61.7 bits (143), Expect = 3e-09
Identities = 46/177 (25%), Positives = 76/177 (42%), Gaps = 2/177 (1%)
Frame = +3
Query: 297 KNPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVF 476
KNPP + + LP+L + L +D+ L + WAL+ ++ G + + V+ +G
Sbjct: 241 KNPPPEFAKVSPCLPVLSRLLFSSDSDLLA-DACWALSYLSDGPNEKIQAVIDSGVCRRL 299
Query: 477 LQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPFLR-NVT 653
++LLM V A+ A+GNI+ + ++ + LL L+ S P +R
Sbjct: 300 VELLMHNDYKVASPALRAVGNIVTGDDIQTQVILNCSALPCLLHLLSS--PKESIRKEAC 357
Query: 654 WVIVNLCRSKDPPPPLKTIQEILPALNVLILHNDSSVLVDTVWAIXYLTDGGN-EQI 821
W I N+ I P L ++ + + WAI T GG EQI
Sbjct: 358 WTISNITAGNRAQIQAVIDANIFPVLIEILQKAEFRTRKEAAWAITNATSGGTPEQI 414
Score = 53.6 bits (123), Expect = 8e-07
Identities = 40/139 (28%), Positives = 60/139 (43%), Gaps = 4/139 (2%)
Frame = +3
Query: 285 LSCDKNPPIDELIAAGILPILVQCLSRAD----NPALQFETAWALTNIASGTSAQTNKVV 452
LS N I +I +G+ LV+ L D +PAL+ A+ NI +G QT ++
Sbjct: 279 LSDGPNEKIQAVIDSGVCRRLVELLMHNDYKVASPALR-----AVGNIVTGDDIQTQVIL 333
Query: 453 HAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPI 632
+ A+P L LL SP E++ +A W + NI VI+ + P+L I
Sbjct: 334 NCSALPCLLHLLSSPKESIRKEACWTISNITAGNRAQIQAVIDANIF-PVLIEILQKAEF 392
Query: 633 PFLRNVTWVIVNLCRSKDP 689
+ W I N P
Sbjct: 393 RTRKEAAWAITNATSGGTP 411
>AL049795-3|CAI22056.1| 536|Homo sapiens karyopherin alpha 6
(importin alpha 7) protein.
Length = 536
Score = 236 bits (577), Expect = 8e-62
Identities = 122/275 (44%), Positives = 173/275 (62%), Gaps = 9/275 (3%)
Frame = +3
Query: 24 RMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPI----SYSTDEEEIDKNL 191
RM +KN + +EMRRRR E ++LRK KRE+ L KRRNV + + D +D +
Sbjct: 13 RMKSYKNNALNPEEMRRRREEEGIQLRKQKREQQLFKRRNVELINEEAAMFDSLLMDSYV 72
Query: 192 ATTDLDELV----MNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELI-AAGILPILVQC 356
++T + ++ + +++ + QLA Q+ RKLLS + +PPIDE+I ++ V+
Sbjct: 73 SSTTGESVITREMVEMLFSDDSDLQLATTQKFRKLLSKEPSPPIDEVINTPRVVDRFVEF 132
Query: 357 LSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALG 536
L R +N LQFE AWALTNIASGTS QT V+ AGAVP+F++LL S E+V +QAVWALG
Sbjct: 133 LKRNENCTLQFEAAWALTNIASGTSQQTKIVIEAGAVPIFIELLNSDFEDVQEQAVWALG 192
Query: 537 NIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTWVIVNLCRSKDPPPPLKTIQE 716
NI GD V RD+V+ ++ PLL+L+ + RN W + NLCR K+PPP +
Sbjct: 193 NIAGDSSVCRDYVLNCSILNPLLTLLTKSTRLTMTRNAVWALSNLCRGKNPPPEFAKVSP 252
Query: 717 ILPALNVLILHNDSSVLVDTVWAIXYLTDGGNEQI 821
LP L+ L+ +DS +L D WA+ YL+DG NE+I
Sbjct: 253 CLPVLSRLLFSSDSDLLADACWALSYLSDGPNEKI 287
Score = 61.7 bits (143), Expect = 3e-09
Identities = 46/177 (25%), Positives = 76/177 (42%), Gaps = 2/177 (1%)
Frame = +3
Query: 297 KNPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVF 476
KNPP + + LP+L + L +D+ L + WAL+ ++ G + + V+ +G
Sbjct: 241 KNPPPEFAKVSPCLPVLSRLLFSSDSDLLA-DACWALSYLSDGPNEKIQAVIDSGVCRRL 299
Query: 477 LQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPFLR-NVT 653
++LLM V A+ A+GNI+ + ++ + LL L+ S P +R
Sbjct: 300 VELLMHNDYKVASPALRAVGNIVTGDDIQTQVILNCSALPCLLHLLSS--PKESIRKEAC 357
Query: 654 WVIVNLCRSKDPPPPLKTIQEILPALNVLILHNDSSVLVDTVWAIXYLTDGGN-EQI 821
W I N+ I P L ++ + + WAI T GG EQI
Sbjct: 358 WTISNITAGNRAQIQAVIDANIFPVLIEILQKAEFRTRKEAAWAITNATSGGTPEQI 414
Score = 53.6 bits (123), Expect = 8e-07
Identities = 40/139 (28%), Positives = 60/139 (43%), Gaps = 4/139 (2%)
Frame = +3
Query: 285 LSCDKNPPIDELIAAGILPILVQCLSRAD----NPALQFETAWALTNIASGTSAQTNKVV 452
LS N I +I +G+ LV+ L D +PAL+ A+ NI +G QT ++
Sbjct: 279 LSDGPNEKIQAVIDSGVCRRLVELLMHNDYKVASPALR-----AVGNIVTGDDIQTQVIL 333
Query: 453 HAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPI 632
+ A+P L LL SP E++ +A W + NI VI+ + P+L I
Sbjct: 334 NCSALPCLLHLLSSPKESIRKEACWTISNITAGNRAQIQAVIDANIF-PVLIEILQKAEF 392
Query: 633 PFLRNVTWVIVNLCRSKDP 689
+ W I N P
Sbjct: 393 RTRKEAAWAITNATSGGTP 411
>AF060543-1|AAC15233.1| 536|Homo sapiens importin alpha 7 subunit
protein.
Length = 536
Score = 236 bits (577), Expect = 8e-62
Identities = 122/275 (44%), Positives = 173/275 (62%), Gaps = 9/275 (3%)
Frame = +3
Query: 24 RMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPI----SYSTDEEEIDKNL 191
RM +KN + +EMRRRR E ++LRK KRE+ L KRRNV + + D +D +
Sbjct: 13 RMKSYKNNALNPEEMRRRREEEGIQLRKQKREQQLFKRRNVELINEEAAMFDSLLMDSYV 72
Query: 192 ATTDLDELV----MNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELI-AAGILPILVQC 356
++T + ++ + +++ + QLA Q+ RKLLS + +PPIDE+I ++ V+
Sbjct: 73 SSTTGESVITREMVEMLFSDDSDLQLATTQKFRKLLSKEPSPPIDEVINTPRVVDRFVEF 132
Query: 357 LSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALG 536
L R +N LQFE AWALTNIASGTS QT V+ AGAVP+F++LL S E+V +QAVWALG
Sbjct: 133 LKRNENCTLQFEAAWALTNIASGTSQQTKIVIEAGAVPIFIELLNSDFEDVQEQAVWALG 192
Query: 537 NIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTWVIVNLCRSKDPPPPLKTIQE 716
NI GD V RD+V+ ++ PLL+L+ + RN W + NLCR K+PPP +
Sbjct: 193 NIAGDSSVCRDYVLNCSILNPLLTLLTKSTRLTMTRNAVWALSNLCRGKNPPPEFAKVSP 252
Query: 717 ILPALNVLILHNDSSVLVDTVWAIXYLTDGGNEQI 821
LP L+ L+ +DS +L D WA+ YL+DG NE+I
Sbjct: 253 CLPVLSRLLFSSDSDLLADACWALSYLSDGPNEKI 287
Score = 61.7 bits (143), Expect = 3e-09
Identities = 46/177 (25%), Positives = 76/177 (42%), Gaps = 2/177 (1%)
Frame = +3
Query: 297 KNPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVF 476
KNPP + + LP+L + L +D+ L + WAL+ ++ G + + V+ +G
Sbjct: 241 KNPPPEFAKVSPCLPVLSRLLFSSDSDLLA-DACWALSYLSDGPNEKIQAVIDSGVCRRL 299
Query: 477 LQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPFLR-NVT 653
++LLM V A+ A+GNI+ + ++ + LL L+ S P +R
Sbjct: 300 VELLMHNDYKVASPALRAVGNIVTGDDIQTQVILNCSALPCLLHLLSS--PKESIRKEAC 357
Query: 654 WVIVNLCRSKDPPPPLKTIQEILPALNVLILHNDSSVLVDTVWAIXYLTDGGN-EQI 821
W I N+ I P L ++ + + WAI T GG EQI
Sbjct: 358 WTISNITAGNRAQIQAVIDANIFPVLIEILQKAEFRTRKEAAWAITNATSGGTPEQI 414
Score = 53.6 bits (123), Expect = 8e-07
Identities = 40/139 (28%), Positives = 60/139 (43%), Gaps = 4/139 (2%)
Frame = +3
Query: 285 LSCDKNPPIDELIAAGILPILVQCLSRAD----NPALQFETAWALTNIASGTSAQTNKVV 452
LS N I +I +G+ LV+ L D +PAL+ A+ NI +G QT ++
Sbjct: 279 LSDGPNEKIQAVIDSGVCRRLVELLMHNDYKVASPALR-----AVGNIVTGDDIQTQVIL 333
Query: 453 HAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPI 632
+ A+P L LL SP E++ +A W + NI VI+ + P+L I
Sbjct: 334 NCSALPCLLHLLSSPKESIRKEACWTISNITAGNRAQIQAVIDANIF-PVLIEILQKAEF 392
Query: 633 PFLRNVTWVIVNLCRSKDP 689
+ W I N P
Sbjct: 393 RTRKEAAWAITNATSGGTP 411
>S75295-1|AAC60648.1| 538|Homo sapiens nucleoprotein interactor 1
protein.
Length = 538
Score = 234 bits (573), Expect = 2e-61
Identities = 123/280 (43%), Positives = 169/280 (60%), Gaps = 14/280 (5%)
Frame = +3
Query: 24 RMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPISYSTDEEEI--DKNLAT 197
R+ +KN + DEMRRRR E ++LRK KREE L KRRNV + EEE+ D
Sbjct: 10 RLKSYKNKSLNPDEMRRRREEEGLQLRKQKREEQLFKRRNVATAEEETEEEVMSDGGFHE 69
Query: 198 TDLDELVMNAAN-----------AENPEAQLAAVQQCRKLLSCDKNPPIDELIAA-GILP 341
+ + M +++PE QL+A Q+ RKLLS + NPPIDE+I+ G++
Sbjct: 70 AQISNMEMAPGGVITSDMIEMIFSKSPEQQLSATQKFRKLLSKEPNPPIDEVISTPGVVA 129
Query: 342 ILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQA 521
V+ L R +N +LQFE+AW LTNIASG S QT V+ A AVP+F++LL S E+V +QA
Sbjct: 130 RFVEFLKRKENCSLQFESAWVLTNIASGNSLQTRIVIQARAVPIFIELLSSEFEDVQEQA 189
Query: 522 VWALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTWVIVNLCRSKDPPPPL 701
VWALGNI GD + RD+V++ ++ PLL L + RN W + NLCR K PPP
Sbjct: 190 VWALGNIAGDSTMCRDYVLDCNILPPLLQLFSKQNRLTMTRNAVWALSNLCRGKSPPPEF 249
Query: 702 KTIQEILPALNVLILHNDSSVLVDTVWAIXYLTDGGNEQI 821
+ L L+ L+ +D+ VL D WA+ YL+DG N++I
Sbjct: 250 AKVSPCLNVLSWLLFVSDTDVLADACWALSYLSDGPNDKI 289
Score = 57.2 bits (132), Expect = 7e-08
Identities = 44/176 (25%), Positives = 74/176 (42%), Gaps = 1/176 (0%)
Frame = +3
Query: 297 KNPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVF 476
K+PP + + L +L L +D L + WAL+ ++ G + + V+ AG
Sbjct: 243 KSPPPEFAKVSPCLNVLSWLLFVSDTDVLA-DACWALSYLSDGPNDKIQAVIDAGVCRRL 301
Query: 477 LQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTW 656
++LLM V A+ A+GNI+ + ++ ++ LL L+ S + W
Sbjct: 302 VELLMHNDYKVVSPALRAVGNIVTGDDIQTQVILNCSALQSLLHLLSSP-KESIKKEACW 360
Query: 657 VIVNLCRSKDPPPPLKTIQEILPALNVLILHNDSSVLVDTVWAIXYLTDGGN-EQI 821
I N+ I PAL ++ + + WAI T GG+ EQI
Sbjct: 361 TISNITAGNRAQIQTVIDANIFPALISILQTAEFRTRKEAAWAITNATSGGSAEQI 416
Score = 52.8 bits (121), Expect = 1e-06
Identities = 27/100 (27%), Positives = 49/100 (49%), Gaps = 1/100 (1%)
Frame = +3
Query: 318 LIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSP 497
++ L L+ LS + +++ E W ++NI +G AQ V+ A P + +L +
Sbjct: 334 ILNCSALQSLLHLLS-SPKESIKKEACWTISNITAGNRAQIQTVIDANIFPALISILQTA 392
Query: 498 HENVCDQAVWALGNIIGDGPVLR-DFVIELGVVKPLLSLI 614
+A WA+ N G + +++ELG +KPL L+
Sbjct: 393 EFRTRKEAAWAITNATSGGSAEQIKYLVELGCIKPLCDLL 432
Score = 39.5 bits (88), Expect = 0.014
Identities = 27/80 (33%), Positives = 38/80 (47%), Gaps = 1/80 (1%)
Frame = +3
Query: 309 IDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNK-VVHAGAVPVFLQL 485
I +I A I P L+ L A+ + E AWA+TN SG SA+ K +V G + L
Sbjct: 373 IQTVIDANIFPALISILQTAEFRTRK-EAAWAITNATSGGSAEQIKYLVELGCIKPLCDL 431
Query: 486 LMSPHENVCDQAVWALGNII 545
L + A+ L NI+
Sbjct: 432 LTVMDSKIVQVALNGLENIL 451
>AF005361-1|AAC51868.1| 536|Homo sapiens importin alpha 6 protein.
Length = 536
Score = 229 bits (559), Expect = 1e-59
Identities = 122/279 (43%), Positives = 166/279 (59%), Gaps = 13/279 (4%)
Frame = +3
Query: 24 RMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPISYSTDEEEIDKNLATTD 203
RM +KN + EMRRRR E ++LRK KREE L KRRNV + + DE ++ + +D
Sbjct: 10 RMKSYKNKALNPQEMRRRREEEGIQLRKQKREEQLFKRRNVYLPRN-DESMLESPIQDSD 68
Query: 204 LDELV------------MNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELIAA-GILPI 344
+ V + + N + QL A Q+ RKLLS + NPPID++I G++
Sbjct: 69 ISSTVPIPEEGVVTTDMVQMIFSNNADQQLTATQKFRKLLSKEPNPPIDQVIQKPGVVQR 128
Query: 345 LVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAV 524
V+ L R +N LQFE AWALTNIASGT T V+ GAVP+F++LL S HE+V +QAV
Sbjct: 129 FVKFLERNENCTLQFEAAWALTNIASGTFLHTKVVIETGAVPIFIKLLNSEHEDVQEQAV 188
Query: 525 WALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTWVIVNLCRSKDPPPPLK 704
WALGNI GD RDFV+ ++ PLL L+ + + RN W + NLCR K+PPP
Sbjct: 189 WALGNIAGDNAECRDFVLNCEILPPLLELLTNSNRLTTTRNAVWALSNLCRGKNPPPNFS 248
Query: 705 TIQEILPALNVLILHNDSSVLVDTVWAIXYLTDGGNEQI 821
+ L L+ L+ +D VL D WA+ YL+DG N++I
Sbjct: 249 KVSPCLNVLSRLLFSSDPDVLADVCWALSYLSDGPNDKI 287
Score = 56.0 bits (129), Expect = 2e-07
Identities = 44/177 (24%), Positives = 75/177 (42%), Gaps = 2/177 (1%)
Frame = +3
Query: 297 KNPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVF 476
KNPP + + L +L + L +D P + + WAL+ ++ G + + V+ +G
Sbjct: 241 KNPPPNFSKVSPCLNVLSRLLFSSD-PDVLADVCWALSYLSDGPNDKIQAVIDSGVCRRL 299
Query: 477 LQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPFLR-NVT 653
++LLM V A+ A+GNI+ + ++ + LL L+ S P +R
Sbjct: 300 VELLMHNDYKVVSPALRAVGNIVTGDDIQTQVILNCSALPCLLHLLSS--PKESIRKEAC 357
Query: 654 WVIVNLCRSKDPPPPLKTIQEILPALNVLILHNDSSVLVDTVWAIXYLTDGGN-EQI 821
W + N+ I P L ++ + + WAI T GG EQI
Sbjct: 358 WTVSNITAGNRAQIQAVIDANIFPVLIEILQKAEFRTRKEAAWAITNATSGGTPEQI 414
Score = 54.4 bits (125), Expect = 5e-07
Identities = 40/145 (27%), Positives = 59/145 (40%)
Frame = +3
Query: 255 LAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSA 434
LA V LS N I +I +G+ LV+ L D + A+ NI +G
Sbjct: 269 LADVCWALSYLSDGPNDKIQAVIDSGVCRRLVELLMHNDYKVVS-PALRAVGNIVTGDDI 327
Query: 435 QTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLI 614
QT +++ A+P L LL SP E++ +A W + NI VI+ + P+L I
Sbjct: 328 QTQVILNCSALPCLLHLLSSPKESIRKEACWTVSNITAGNRAQIQAVIDANIF-PVLIEI 386
Query: 615 KSDIPIPFLRNVTWVIVNLCRSKDP 689
+ W I N P
Sbjct: 387 LQKAEFRTRKEAAWAITNATSGGTP 411
>BC047409-1|AAH47409.1| 539|Homo sapiens karyopherin alpha 5
(importin alpha 6) protein.
Length = 539
Score = 228 bits (557), Expect = 2e-59
Identities = 122/279 (43%), Positives = 164/279 (58%), Gaps = 13/279 (4%)
Frame = +3
Query: 24 RMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPISYSTDEEEIDKNLATTD 203
RM +KN + EMRRRR E ++LRK KREE L KRRNV + DE ++ + D
Sbjct: 13 RMKSYKNKALNPQEMRRRREEEGIQLRKQKREEQLFKRRNVYLP-RNDESMLESPIQDPD 71
Query: 204 LDELV------------MNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELI-AAGILPI 344
+ V + + N + QL A Q+ RKLLS + NPPID++I G++
Sbjct: 72 ISSTVPIPEEEVVTTDMVQMIFSNNADQQLTATQKFRKLLSKEPNPPIDQVIQKPGVVQR 131
Query: 345 LVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAV 524
V+ L R +N LQFE AWALTNIASGT T V+ GAVP+F++LL S HE+V +QAV
Sbjct: 132 FVKFLERNENCTLQFEAAWALTNIASGTFLHTKVVIETGAVPIFIKLLNSEHEDVQEQAV 191
Query: 525 WALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTWVIVNLCRSKDPPPPLK 704
WALGNI GD RDFV+ ++ PLL L+ + + RN W + NLCR K+PPP
Sbjct: 192 WALGNIAGDNAECRDFVLNCEILPPLLELLTNSNRLTTTRNAVWALSNLCRGKNPPPNFS 251
Query: 705 TIQEILPALNVLILHNDSSVLVDTVWAIXYLTDGGNEQI 821
+ L L+ L+ +D VL D WA+ YL+DG N++I
Sbjct: 252 KVSPCLNVLSRLLFSSDPDVLADVCWALSYLSDGPNDKI 290
Score = 56.0 bits (129), Expect = 2e-07
Identities = 44/177 (24%), Positives = 75/177 (42%), Gaps = 2/177 (1%)
Frame = +3
Query: 297 KNPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVF 476
KNPP + + L +L + L +D P + + WAL+ ++ G + + V+ +G
Sbjct: 244 KNPPPNFSKVSPCLNVLSRLLFSSD-PDVLADVCWALSYLSDGPNDKIQAVIDSGVCRRL 302
Query: 477 LQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPFLR-NVT 653
++LLM V A+ A+GNI+ + ++ + LL L+ S P +R
Sbjct: 303 VELLMHNDYKVVSPALRAVGNIVTGDDIQTQVILNCSALPCLLHLLSS--PKESIRKEAC 360
Query: 654 WVIVNLCRSKDPPPPLKTIQEILPALNVLILHNDSSVLVDTVWAIXYLTDGGN-EQI 821
W + N+ I P L ++ + + WAI T GG EQI
Sbjct: 361 WTVSNITAGNRAQIQAVIDANIFPVLIEILQKAEFRTRKEAAWAITNATSGGTPEQI 417
Score = 54.4 bits (125), Expect = 5e-07
Identities = 40/145 (27%), Positives = 59/145 (40%)
Frame = +3
Query: 255 LAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSA 434
LA V LS N I +I +G+ LV+ L D + A+ NI +G
Sbjct: 272 LADVCWALSYLSDGPNDKIQAVIDSGVCRRLVELLMHNDYKVVS-PALRAVGNIVTGDDI 330
Query: 435 QTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLI 614
QT +++ A+P L LL SP E++ +A W + NI VI+ + P+L I
Sbjct: 331 QTQVILNCSALPCLLHLLSSPKESIRKEACWTVSNITAGNRAQIQAVIDANIF-PVLIEI 389
Query: 615 KSDIPIPFLRNVTWVIVNLCRSKDP 689
+ W I N P
Sbjct: 390 LQKAEFRTRKEAAWAITNATSGGTP 414
>AL132795-5|CAI20500.1| 539|Homo sapiens karyopherin alpha 5
(importin alpha 6) protein.
Length = 539
Score = 228 bits (557), Expect = 2e-59
Identities = 122/279 (43%), Positives = 164/279 (58%), Gaps = 13/279 (4%)
Frame = +3
Query: 24 RMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPISYSTDEEEIDKNLATTD 203
RM +KN + EMRRRR E ++LRK KREE L KRRNV + DE ++ + D
Sbjct: 13 RMKSYKNKALNPQEMRRRREEEGIQLRKQKREEQLFKRRNVYLP-RNDESMLESPIQDPD 71
Query: 204 LDELV------------MNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELI-AAGILPI 344
+ V + + N + QL A Q+ RKLLS + NPPID++I G++
Sbjct: 72 ISSTVPIPEEEVVTTDMVQMIFSNNADQQLTATQKFRKLLSKEPNPPIDQVIQKPGVVQR 131
Query: 345 LVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAV 524
V+ L R +N LQFE AWALTNIASGT T V+ GAVP+F++LL S HE+V +QAV
Sbjct: 132 FVKFLERNENCTLQFEAAWALTNIASGTFLHTKVVIETGAVPIFIKLLNSEHEDVQEQAV 191
Query: 525 WALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTWVIVNLCRSKDPPPPLK 704
WALGNI GD RDFV+ ++ PLL L+ + + RN W + NLCR K+PPP
Sbjct: 192 WALGNIAGDNAECRDFVLNCEILPPLLELLTNSNRLTTTRNAVWALSNLCRGKNPPPNFS 251
Query: 705 TIQEILPALNVLILHNDSSVLVDTVWAIXYLTDGGNEQI 821
+ L L+ L+ +D VL D WA+ YL+DG N++I
Sbjct: 252 KVSPCLNVLSRLLFSSDPDVLADVCWALSYLSDGPNDKI 290
Score = 56.0 bits (129), Expect = 2e-07
Identities = 44/177 (24%), Positives = 75/177 (42%), Gaps = 2/177 (1%)
Frame = +3
Query: 297 KNPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVF 476
KNPP + + L +L + L +D P + + WAL+ ++ G + + V+ +G
Sbjct: 244 KNPPPNFSKVSPCLNVLSRLLFSSD-PDVLADVCWALSYLSDGPNDKIQAVIDSGVCRRL 302
Query: 477 LQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPFLR-NVT 653
++LLM V A+ A+GNI+ + ++ + LL L+ S P +R
Sbjct: 303 VELLMHNDYKVVSPALRAVGNIVTGDDIQTQVILNCSALPCLLHLLSS--PKESIRKEAC 360
Query: 654 WVIVNLCRSKDPPPPLKTIQEILPALNVLILHNDSSVLVDTVWAIXYLTDGGN-EQI 821
W + N+ I P L ++ + + WAI T GG EQI
Sbjct: 361 WTVSNITAGNRAQIQAVIDANIFPVLIEILQKAEFRTRKEAAWAITNATSGGTPEQI 417
Score = 54.4 bits (125), Expect = 5e-07
Identities = 40/145 (27%), Positives = 59/145 (40%)
Frame = +3
Query: 255 LAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSA 434
LA V LS N I +I +G+ LV+ L D + A+ NI +G
Sbjct: 272 LADVCWALSYLSDGPNDKIQAVIDSGVCRRLVELLMHNDYKVVS-PALRAVGNIVTGDDI 330
Query: 435 QTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLI 614
QT +++ A+P L LL SP E++ +A W + NI VI+ + P+L I
Sbjct: 331 QTQVILNCSALPCLLHLLSSPKESIRKEACWTVSNITAGNRAQIQAVIDANIF-PVLIEI 389
Query: 615 KSDIPIPFLRNVTWVIVNLCRSKDP 689
+ W I N P
Sbjct: 390 LQKAEFRTRKEAAWAITNATSGGTP 414
>AL049795-1|CAI22054.1| 321|Homo sapiens karyopherin alpha 6
(importin alpha 7) protein.
Length = 321
Score = 115 bits (277), Expect = 2e-25
Identities = 57/153 (37%), Positives = 83/153 (54%), Gaps = 1/153 (0%)
Frame = +3
Query: 366 ADNPALQFETAWALTNIASGT-SAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNI 542
+D+ LQ T + S S ++V++ V + +EN QAVWALGNI
Sbjct: 42 SDDSDLQLATTQKFRKLLSKEPSPPIDEVINTPRVVDRFVEFLKRNENCTLQAVWALGNI 101
Query: 543 IGDGPVLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTWVIVNLCRSKDPPPPLKTIQEIL 722
GD V RD+V+ ++ PLL+L+ + RN W + NLCR K+PPP + L
Sbjct: 102 AGDSSVCRDYVLNCSILNPLLTLLTKSTRLTMTRNAVWALSNLCRGKNPPPEFAKVSPCL 161
Query: 723 PALNVLILHNDSSVLVDTVWAIXYLTDGGNEQI 821
P L+ L+ +DS +L D WA+ YL+DG NE+I
Sbjct: 162 PVLSRLLFSSDSDLLADACWALSYLSDGPNEKI 194
Score = 68.1 bits (159), Expect = 4e-11
Identities = 56/199 (28%), Positives = 94/199 (47%), Gaps = 4/199 (2%)
Frame = +3
Query: 234 AENPEAQLAAVQQCRKLLSCDKNPPIDELI-AAGILPILVQCLSRADNPALQFETAWALT 410
+++ + QLA Q+ RKLLS + +PPIDE+I ++ V+ L R +N LQ WAL
Sbjct: 42 SDDSDLQLATTQKFRKLLSKEPSPPIDEVINTPRVVDRFVEFLKRNENCTLQ--AVWALG 99
Query: 411 NIASGTSAQTNKVVHAGAV-PVFLQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELG 587
NIA +S + V++ + P+ L S + AVWAL N+ +F ++
Sbjct: 100 NIAGDSSVCRDYVLNCSILNPLLTLLTKSTRLTMTRNAVWALSNLCRGKNPPPEFA-KVS 158
Query: 588 VVKPLLSLIKSDIPIPFLRNVTWVIVNLCRSKDPPPPLKTIQE--ILPALNVLILHNDSS 761
P+LS + L + W + L S P ++ + + + L L++HND
Sbjct: 159 PCLPVLSRLLFSSDSDLLADACWALSYL--SDGPNEKIQAVIDSGVCRRLVELLMHNDYK 216
Query: 762 VLVDTVWAIXYLTDGGNEQ 818
V + A+ + G + Q
Sbjct: 217 VASPALRAVGNIVTGDDIQ 235
Score = 61.7 bits (143), Expect = 3e-09
Identities = 46/177 (25%), Positives = 76/177 (42%), Gaps = 2/177 (1%)
Frame = +3
Query: 297 KNPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVF 476
KNPP + + LP+L + L +D+ L + WAL+ ++ G + + V+ +G
Sbjct: 148 KNPPPEFAKVSPCLPVLSRLLFSSDSDLLA-DACWALSYLSDGPNEKIQAVIDSGVCRRL 206
Query: 477 LQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPFLR-NVT 653
++LLM V A+ A+GNI+ + ++ + LL L+ S P +R
Sbjct: 207 VELLMHNDYKVASPALRAVGNIVTGDDIQTQVILNCSALPCLLHLLSS--PKESIRKEAC 264
Query: 654 WVIVNLCRSKDPPPPLKTIQEILPALNVLILHNDSSVLVDTVWAIXYLTDGGN-EQI 821
W I N+ I P L ++ + + WAI T GG EQI
Sbjct: 265 WTISNITAGNRAQIQAVIDANIFPVLIEILQKAEFRTRKEAAWAITNATSGGTPEQI 321
Score = 53.6 bits (123), Expect = 8e-07
Identities = 40/139 (28%), Positives = 60/139 (43%), Gaps = 4/139 (2%)
Frame = +3
Query: 285 LSCDKNPPIDELIAAGILPILVQCLSRAD----NPALQFETAWALTNIASGTSAQTNKVV 452
LS N I +I +G+ LV+ L D +PAL+ A+ NI +G QT ++
Sbjct: 186 LSDGPNEKIQAVIDSGVCRRLVELLMHNDYKVASPALR-----AVGNIVTGDDIQTQVIL 240
Query: 453 HAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPI 632
+ A+P L LL SP E++ +A W + NI VI+ + P+L I
Sbjct: 241 NCSALPCLLHLLSSPKESIRKEACWTISNITAGNRAQIQAVIDANIF-PVLIEILQKAEF 299
Query: 633 PFLRNVTWVIVNLCRSKDP 689
+ W I N P
Sbjct: 300 RTRKEAAWAITNATSGGTP 318
>AL132795-6|CAI20501.1| 142|Homo sapiens karyopherin alpha 5
(importin alpha 6) protein.
Length = 142
Score = 76.6 bits (180), Expect = 1e-13
Identities = 51/134 (38%), Positives = 71/134 (52%), Gaps = 13/134 (9%)
Frame = +3
Query: 24 RMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPISYSTDEEEIDKNLATTD 203
RM +KN + EMRRRR E ++LRK KREE L KRRNV + DE ++ + D
Sbjct: 10 RMKSYKNKALNPQEMRRRREEEGIQLRKQKREEQLFKRRNVYLP-RNDESMLESPIQDPD 68
Query: 204 LDELV------------MNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELI-AAGILPI 344
+ V + + N + QL A Q+ RKLLS + NPPID++I G++
Sbjct: 69 ISSTVPIPEEEVVTTDMVQMIFSNNADQQLTATQKFRKLLSKEPNPPIDQVIQKPGVVQR 128
Query: 345 LVQCLSRADNPALQ 386
V+ L R +N LQ
Sbjct: 129 FVKFLERNENCTLQ 142
>Y12393-1|CAA73025.1| 281|Homo sapiens SRP1-like protein protein.
Length = 281
Score = 59.7 bits (138), Expect = 1e-08
Identities = 27/36 (75%), Positives = 30/36 (83%)
Frame = +3
Query: 714 EILPALNVLILHNDSSVLVDTVWAIXYLTDGGNEQI 821
EILPAL VLI H D ++LVDTVWA+ YLTD GNEQI
Sbjct: 2 EILPALCVLIHHTDVNILVDTVWALSYLTDAGNEQI 37
Score = 58.8 bits (136), Expect = 2e-08
Identities = 48/158 (30%), Positives = 72/158 (45%), Gaps = 2/158 (1%)
Frame = +3
Query: 300 NPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFL 479
N I +I +GI+P LV LS + +Q A+ NI +GT QT V++ A+ F
Sbjct: 34 NEQIQMVIDSGIVPHLVPLLSHQE-VKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFP 92
Query: 480 QLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLI-KSDIPIPFLRNVTW 656
LL P E + +AVW L NI VI+ +V ++ L+ K D + W
Sbjct: 93 ALLTHPKEKINKEAVWFLSNITAGNQQQVQAVIDANLVPMIIHLLDKGDFGTQ--KEAAW 150
Query: 657 VIVNLCRSKDPPPPLKTIQE-ILPALNVLILHNDSSVL 767
I NL S IQ+ ++P L+ D+ V+
Sbjct: 151 AISNLTISGRKDQVAYLIQQNVIPPFCNLLTVKDAQVV 188
Score = 34.7 bits (76), Expect = 0.41
Identities = 25/119 (21%), Positives = 45/119 (37%)
Frame = +3
Query: 465 VPVFLQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPFLR 644
+P L+ N+ VWAL + G VI+ G+V L+ L+ S +
Sbjct: 4 LPALCVLIHHTDVNILVDTVWALSYLTDAGNEQIQMVIDSGIVPHLVPLL-SHQEVKVQT 62
Query: 645 NVTWVIVNLCRSKDPPPPLKTIQEILPALNVLILHNDSSVLVDTVWAIXYLTDGGNEQI 821
+ N+ D + + L L+ H + + VW + +T G +Q+
Sbjct: 63 AALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKINKEAVWFLSNITAGNQQQV 121
>BC030585-1|AAH30585.1| 458|Homo sapiens sperm associated antigen 6
protein.
Length = 458
Score = 52.4 bits (120), Expect = 2e-06
Identities = 33/99 (33%), Positives = 48/99 (48%)
Frame = +3
Query: 318 LIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSP 497
++ G L LV CL D P ++ AWAL IA + + VV AGAVP+ + + P
Sbjct: 121 IVDCGALDTLVICLEDFD-PGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLVLCIQEP 179
Query: 498 HENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLI 614
+ A AL +I+ P L V++ G V L +I
Sbjct: 180 EIALKGIAASALSDIVKHSPELAQTVVDAGAVAHLAQMI 218
Score = 44.0 bits (99), Expect = 7e-04
Identities = 28/100 (28%), Positives = 51/100 (51%)
Frame = +3
Query: 318 LIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSP 497
++ AG +P+LV C+ + AL+ A AL++I + VV AGAV Q++++P
Sbjct: 163 VVDAGAVPLLVLCIQEPEI-ALKGIAASALSDIVKHSPELAQTVVDAGAVAHLAQMILNP 221
Query: 498 HENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIK 617
+ Q + AL + L + V+E + +L+ +K
Sbjct: 222 DAKLKHQILSALSQVSKHSVDLAEMVVEAEIFPVVLTCLK 261
Score = 34.7 bits (76), Expect = 0.41
Identities = 33/121 (27%), Positives = 49/121 (40%), Gaps = 9/121 (7%)
Frame = +3
Query: 159 STDEEEIDKNLATTDLDELVMNAANAE---------NPEAQLAAVQQCRKLLSCDKNPPI 311
ST EI K+ T +L +LV+NA +L + + + +N +
Sbjct: 272 STLIREIAKH--TPELSQLVVNAGGVAAVIDCIGSCKGNTRLPGIMMLGYVAAHSENLAM 329
Query: 312 DELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLM 491
+I+ G+ P L CLS ++ AWAL I T V +PV L L M
Sbjct: 330 AVIISKGV-PQLSVCLSEEPEDHIKAAAAWALGQIGRHTPEHARAVAVTNTLPVLLSLYM 388
Query: 492 S 494
S
Sbjct: 389 S 389
>CR533552-1|CAG38583.1| 509|Homo sapiens SPAG6 protein.
Length = 509
Score = 50.4 bits (115), Expect = 8e-06
Identities = 33/99 (33%), Positives = 47/99 (47%)
Frame = +3
Query: 318 LIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSP 497
++ G L LV CL D P ++ AWAL IA + + VV AGAVP+ + + P
Sbjct: 121 IVDCGALDTLVICLEDFD-PGVKEAAAWALRYIARHNAELSRAVVDAGAVPLLVLCIQEP 179
Query: 498 HENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLI 614
+ A AL +I P L V++ G V L +I
Sbjct: 180 EIALKRIAASALSDIAKHSPELAQTVVDAGAVAHLAQMI 218
Score = 45.6 bits (103), Expect = 2e-04
Identities = 29/100 (29%), Positives = 52/100 (52%)
Frame = +3
Query: 318 LIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSP 497
++ AG +P+LV C+ + AL+ A AL++IA + VV AGAV Q++++P
Sbjct: 163 VVDAGAVPLLVLCIQEPEI-ALKRIAASALSDIAKHSPELAQTVVDAGAVAHLAQMILNP 221
Query: 498 HENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIK 617
+ Q + AL + L + V+E + +L+ +K
Sbjct: 222 DAKLKHQILSALSQVSKHSVDLAEMVVEAEIFPVVLTCLK 261
Score = 34.7 bits (76), Expect = 0.41
Identities = 33/121 (27%), Positives = 49/121 (40%), Gaps = 9/121 (7%)
Frame = +3
Query: 159 STDEEEIDKNLATTDLDELVMNAANAE---------NPEAQLAAVQQCRKLLSCDKNPPI 311
ST EI K+ T +L +LV+NA +L + + + +N +
Sbjct: 272 STLIREIAKH--TPELSQLVVNAGGVAAVIDCIGSCKGNTRLPGIMMLGYVAAHSENLAM 329
Query: 312 DELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLM 491
+I+ G+ P L CLS ++ AWAL I T V +PV L L M
Sbjct: 330 AVIISKGV-PQLSVCLSEEPEDHIKAAAAWALGQIGRHTPEHARAVAVTNTLPVLLSLYM 388
Query: 492 S 494
S
Sbjct: 389 S 389
>AL513128-4|CAH72210.1| 509|Homo sapiens sperm associated antigen 6
protein.
Length = 509
Score = 50.4 bits (115), Expect = 8e-06
Identities = 33/99 (33%), Positives = 47/99 (47%)
Frame = +3
Query: 318 LIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSP 497
++ G L LV CL D P ++ AWAL IA + + VV AGAVP+ + + P
Sbjct: 121 IVDCGALDTLVICLEDFD-PGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLVLCIQEP 179
Query: 498 HENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLI 614
+ A AL +I P L V++ G V L +I
Sbjct: 180 EIALKRIAASALSDIAKHSPELAQTVVDAGAVAHLAQMI 218
Score = 45.6 bits (103), Expect = 2e-04
Identities = 29/100 (29%), Positives = 52/100 (52%)
Frame = +3
Query: 318 LIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSP 497
++ AG +P+LV C+ + AL+ A AL++IA + VV AGAV Q++++P
Sbjct: 163 VVDAGAVPLLVLCIQEPEI-ALKRIAASALSDIAKHSPELAQTVVDAGAVAHLAQMILNP 221
Query: 498 HENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIK 617
+ Q + AL + L + V+E + +L+ +K
Sbjct: 222 DAKLKHQILSALSQVSKHSVDLAEMVVEAEIFPVVLTCLK 261
Score = 34.7 bits (76), Expect = 0.41
Identities = 33/121 (27%), Positives = 49/121 (40%), Gaps = 9/121 (7%)
Frame = +3
Query: 159 STDEEEIDKNLATTDLDELVMNAANAE---------NPEAQLAAVQQCRKLLSCDKNPPI 311
ST EI K+ T +L +LV+NA +L + + + +N +
Sbjct: 272 STLIREIAKH--TPELSQLVVNAGGVAAVIDCIGSCKGNTRLPGIMMLGYVAAHSENLAM 329
Query: 312 DELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLM 491
+I+ G+ P L CLS ++ AWAL I T V +PV L L M
Sbjct: 330 AVIISKGV-PQLSVCLSEEPEDHIKAAAAWALGQIGRHTPEHARAVAVTNTLPVLLSLYM 388
Query: 492 S 494
S
Sbjct: 389 S 389
>AL513128-3|CAH72209.1| 458|Homo sapiens sperm associated antigen 6
protein.
Length = 458
Score = 50.4 bits (115), Expect = 8e-06
Identities = 33/99 (33%), Positives = 47/99 (47%)
Frame = +3
Query: 318 LIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSP 497
++ G L LV CL D P ++ AWAL IA + + VV AGAVP+ + + P
Sbjct: 121 IVDCGALDTLVICLEDFD-PGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLVLCIQEP 179
Query: 498 HENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLI 614
+ A AL +I P L V++ G V L +I
Sbjct: 180 EIALKRIAASALSDIAKHSPELAQTVVDAGAVAHLAQMI 218
Score = 45.6 bits (103), Expect = 2e-04
Identities = 29/100 (29%), Positives = 52/100 (52%)
Frame = +3
Query: 318 LIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSP 497
++ AG +P+LV C+ + AL+ A AL++IA + VV AGAV Q++++P
Sbjct: 163 VVDAGAVPLLVLCIQEPEI-ALKRIAASALSDIAKHSPELAQTVVDAGAVAHLAQMILNP 221
Query: 498 HENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIK 617
+ Q + AL + L + V+E + +L+ +K
Sbjct: 222 DAKLKHQILSALSQVSKHSVDLAEMVVEAEIFPVVLTCLK 261
Score = 34.7 bits (76), Expect = 0.41
Identities = 33/121 (27%), Positives = 49/121 (40%), Gaps = 9/121 (7%)
Frame = +3
Query: 159 STDEEEIDKNLATTDLDELVMNAANAE---------NPEAQLAAVQQCRKLLSCDKNPPI 311
ST EI K+ T +L +LV+NA +L + + + +N +
Sbjct: 272 STLIREIAKH--TPELSQLVVNAGGVAAVIDCIGSCKGNTRLPGIMMLGYVAAHSENLAM 329
Query: 312 DELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLM 491
+I+ G+ P L CLS ++ AWAL I T V +PV L L M
Sbjct: 330 AVIISKGV-PQLSVCLSEEPEDHIKAAAAWALGQIGRHTPEHARAVAVTNTLPVLLSLYM 388
Query: 492 S 494
S
Sbjct: 389 S 389
>AL158211-15|CAI15963.1| 509|Homo sapiens sperm associated antigen
6 protein.
Length = 509
Score = 50.4 bits (115), Expect = 8e-06
Identities = 33/99 (33%), Positives = 47/99 (47%)
Frame = +3
Query: 318 LIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSP 497
++ G L LV CL D P ++ AWAL IA + + VV AGAVP+ + + P
Sbjct: 121 IVDCGALDTLVICLEDFD-PGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLVLCIQEP 179
Query: 498 HENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLI 614
+ A AL +I P L V++ G V L +I
Sbjct: 180 EIALKRIAASALSDIAKHSPELAQTVVDAGAVAHLAQMI 218
Score = 45.6 bits (103), Expect = 2e-04
Identities = 29/100 (29%), Positives = 52/100 (52%)
Frame = +3
Query: 318 LIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSP 497
++ AG +P+LV C+ + AL+ A AL++IA + VV AGAV Q++++P
Sbjct: 163 VVDAGAVPLLVLCIQEPEI-ALKRIAASALSDIAKHSPELAQTVVDAGAVAHLAQMILNP 221
Query: 498 HENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIK 617
+ Q + AL + L + V+E + +L+ +K
Sbjct: 222 DAKLKHQILSALSQVSKHSVDLAEMVVEAEIFPVVLTCLK 261
Score = 34.7 bits (76), Expect = 0.41
Identities = 33/121 (27%), Positives = 49/121 (40%), Gaps = 9/121 (7%)
Frame = +3
Query: 159 STDEEEIDKNLATTDLDELVMNAANAE---------NPEAQLAAVQQCRKLLSCDKNPPI 311
ST EI K+ T +L +LV+NA +L + + + +N +
Sbjct: 272 STLIREIAKH--TPELSQLVVNAGGVAAVIDCIGSCKGNTRLPGIMMLGYVAAHSENLAM 329
Query: 312 DELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLM 491
+I+ G+ P L CLS ++ AWAL I T V +PV L L M
Sbjct: 330 AVIISKGV-PQLSVCLSEEPEDHIKAAAAWALGQIGRHTPEHARAVAVTNTLPVLLSLYM 388
Query: 492 S 494
S
Sbjct: 389 S 389
>AL158211-14|CAI15962.1| 458|Homo sapiens sperm associated antigen
6 protein.
Length = 458
Score = 50.4 bits (115), Expect = 8e-06
Identities = 33/99 (33%), Positives = 47/99 (47%)
Frame = +3
Query: 318 LIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSP 497
++ G L LV CL D P ++ AWAL IA + + VV AGAVP+ + + P
Sbjct: 121 IVDCGALDTLVICLEDFD-PGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLVLCIQEP 179
Query: 498 HENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLI 614
+ A AL +I P L V++ G V L +I
Sbjct: 180 EIALKRIAASALSDIAKHSPELAQTVVDAGAVAHLAQMI 218
Score = 45.6 bits (103), Expect = 2e-04
Identities = 29/100 (29%), Positives = 52/100 (52%)
Frame = +3
Query: 318 LIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSP 497
++ AG +P+LV C+ + AL+ A AL++IA + VV AGAV Q++++P
Sbjct: 163 VVDAGAVPLLVLCIQEPEI-ALKRIAASALSDIAKHSPELAQTVVDAGAVAHLAQMILNP 221
Query: 498 HENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIK 617
+ Q + AL + L + V+E + +L+ +K
Sbjct: 222 DAKLKHQILSALSQVSKHSVDLAEMVVEAEIFPVVLTCLK 261
Score = 34.7 bits (76), Expect = 0.41
Identities = 33/121 (27%), Positives = 49/121 (40%), Gaps = 9/121 (7%)
Frame = +3
Query: 159 STDEEEIDKNLATTDLDELVMNAANAE---------NPEAQLAAVQQCRKLLSCDKNPPI 311
ST EI K+ T +L +LV+NA +L + + + +N +
Sbjct: 272 STLIREIAKH--TPELSQLVVNAGGVAAVIDCIGSCKGNTRLPGIMMLGYVAAHSENLAM 329
Query: 312 DELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLM 491
+I+ G+ P L CLS ++ AWAL I T V +PV L L M
Sbjct: 330 AVIISKGV-PQLSVCLSEEPEDHIKAAAAWALGQIGRHTPEHARAVAVTNTLPVLLSLYM 388
Query: 492 S 494
S
Sbjct: 389 S 389
>AF079363-1|AAC32590.1| 509|Homo sapiens sperm flagellar protein
Repro-SA-1 protein.
Length = 509
Score = 50.4 bits (115), Expect = 8e-06
Identities = 33/99 (33%), Positives = 47/99 (47%)
Frame = +3
Query: 318 LIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSP 497
++ G L LV CL D P ++ AWAL IA + + VV AGAVP+ + + P
Sbjct: 121 IVDCGALDTLVICLEDFD-PGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLVLCIQEP 179
Query: 498 HENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLI 614
+ A AL +I P L V++ G V L +I
Sbjct: 180 EIALKRIAASALSDIAKHSPELAQTVVDAGAVAHLAQMI 218
Score = 45.6 bits (103), Expect = 2e-04
Identities = 29/100 (29%), Positives = 52/100 (52%)
Frame = +3
Query: 318 LIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSP 497
++ AG +P+LV C+ + AL+ A AL++IA + VV AGAV Q++++P
Sbjct: 163 VVDAGAVPLLVLCIQEPEI-ALKRIAASALSDIAKHSPELAQTVVDAGAVAHLAQMILNP 221
Query: 498 HENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIK 617
+ Q + AL + L + V+E + +L+ +K
Sbjct: 222 DAKLKHQILSALSQVSKHSVDLAEMVVEAEIFPVVLTCLK 261
Score = 34.7 bits (76), Expect = 0.41
Identities = 33/121 (27%), Positives = 49/121 (40%), Gaps = 9/121 (7%)
Frame = +3
Query: 159 STDEEEIDKNLATTDLDELVMNAANAE---------NPEAQLAAVQQCRKLLSCDKNPPI 311
ST EI K+ T +L +LV+NA +L + + + +N +
Sbjct: 272 STLIREIAKH--TPELSQLVVNAGGVAAVIDCIGSCKGNTRLPGIMMLGYVAAHSENLAM 329
Query: 312 DELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLM 491
+I+ G+ P L CLS ++ AWAL I T V +PV L L M
Sbjct: 330 AVIISKGV-PQLSVCLSEEPEDHIKAAAAWALGQIGRHTPEHARAVAVTNTLPVLLSLYM 388
Query: 492 S 494
S
Sbjct: 389 S 389
>AY217348-1|AAO45101.1| 725|Homo sapiens FLJ00019-like protein
protein.
Length = 725
Score = 41.5 bits (93), Expect = 0.004
Identities = 31/95 (32%), Positives = 48/95 (50%)
Frame = +3
Query: 330 GILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENV 509
GILP LV L ++Q TA AL N+A + + AGAVP+ ++ L + ++
Sbjct: 154 GILP-LVTILQCMKTDSIQNRTARALGNLAMEPES-CGDIHCAGAVPLLVESLTACQDSQ 211
Query: 510 CDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLI 614
C Q+V + D P R + + G V+PL L+
Sbjct: 212 CLQSVVRALRNLADSPQHRLALAQQGAVRPLAELL 246
>AK024430-1|BAB15720.1| 732|Homo sapiens FLJ00019 protein protein.
Length = 732
Score = 41.1 bits (92), Expect = 0.005
Identities = 31/95 (32%), Positives = 48/95 (50%)
Frame = +3
Query: 330 GILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENV 509
GILP LV L ++Q TA AL N+A + + AGAVP+ ++ L + ++
Sbjct: 161 GILP-LVTILQCMKTDSVQNRTARALGNLAMEPES-CGDIHCAGAVPLLVESLTACQDSQ 218
Query: 510 CDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLI 614
C Q+V + D P R + + G V+PL L+
Sbjct: 219 CLQSVVRALRNLADSPQHRLALAQQGAVRPLAELL 253
>X63465-1|CAA45067.1| 558|Homo sapiens smg GDS protein.
Length = 558
Score = 37.1 bits (82), Expect = 0.077
Identities = 40/144 (27%), Positives = 62/144 (43%), Gaps = 1/144 (0%)
Frame = +3
Query: 186 NLATTDLDELVMNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELI-AAGILPILVQCLS 362
NL+ T L +L + A + E L C N E I A+GIL + L+
Sbjct: 3 NLSDT-LKKLKITAV--DKTEDSLEGCLDCLLQALAQNNTETSEKIQASGILQLFASLLT 59
Query: 363 RADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNI 542
+ + + A + +A + V AG + +QLL S + V Q ALGNI
Sbjct: 60 --PQSSCKAKVANIIAEVAKNEFMRI-PCVDAGLISPLVQLLNSKDQEVLLQTGRALGNI 116
Query: 543 IGDGPVLRDFVIELGVVKPLLSLI 614
D L+ +I +GV+ L+ L+
Sbjct: 117 CYDSHSLQAQLINMGVIPTLVKLL 140
>BC099845-1|AAH99845.1| 559|Homo sapiens RAP1GDS1 protein protein.
Length = 559
Score = 37.1 bits (82), Expect = 0.077
Identities = 40/144 (27%), Positives = 62/144 (43%), Gaps = 1/144 (0%)
Frame = +3
Query: 186 NLATTDLDELVMNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELI-AAGILPILVQCLS 362
NL+ T L +L + A + E L C N E I A+GIL + L+
Sbjct: 4 NLSDT-LKKLKITAV--DKTEDSLEGCLDCLLQALAQNNTETSEKIQASGILQLFASLLT 60
Query: 363 RADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNI 542
+ + + A + +A + V AG + +QLL S + V Q ALGNI
Sbjct: 61 --PQSSCKAKVANIIAEVAKNEFMRI-PCVDAGLISPLVQLLNSKDQEVLLQTGRALGNI 117
Query: 543 IGDGPVLRDFVIELGVVKPLLSLI 614
D L+ +I +GV+ L+ L+
Sbjct: 118 CYDSHSLQAQLINMGVIPTLVKLL 141
>BC099708-1|AAH99708.1| 558|Homo sapiens RAP1GDS1 protein protein.
Length = 558
Score = 37.1 bits (82), Expect = 0.077
Identities = 40/144 (27%), Positives = 62/144 (43%), Gaps = 1/144 (0%)
Frame = +3
Query: 186 NLATTDLDELVMNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELI-AAGILPILVQCLS 362
NL+ T L +L + A + E L C N E I A+GIL + L+
Sbjct: 3 NLSDT-LKKLKITAV--DKTEDSLEGCLDCLLQALAQNNTETSEKIQASGILQLFASLLT 59
Query: 363 RADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNI 542
+ + + A + +A + V AG + +QLL S + V Q ALGNI
Sbjct: 60 --PQSSCKAKVANIIAEVAKNEFMRI-PCVDAGLISPLVQLLNSKDQEVLLQTGRALGNI 116
Query: 543 IGDGPVLRDFVIELGVVKPLLSLI 614
D L+ +I +GV+ L+ L+
Sbjct: 117 CYDSHSLQAQLINMGVIPTLVKLL 140
>BC098334-1|AAH98334.1| 558|Homo sapiens RAP1GDS1 protein protein.
Length = 558
Score = 37.1 bits (82), Expect = 0.077
Identities = 40/144 (27%), Positives = 62/144 (43%), Gaps = 1/144 (0%)
Frame = +3
Query: 186 NLATTDLDELVMNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELI-AAGILPILVQCLS 362
NL+ T L +L + A + E L C N E I A+GIL + L+
Sbjct: 3 NLSDT-LKKLKITAV--DKTEDSLEGCLDCLLQALAQNNTETSEKIQASGILQLFASLLT 59
Query: 363 RADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNI 542
+ + + A + +A + V AG + +QLL S + V Q ALGNI
Sbjct: 60 --PQSSCKAKVANIIAEVAKNEFMRI-PCVDAGLISPLVQLLNSKDQEVLLQTGRALGNI 116
Query: 543 IGDGPVLRDFVIELGVVKPLLSLI 614
D L+ +I +GV+ L+ L+
Sbjct: 117 CYDSHSLQAQLINMGVIPTLVKLL 140
>BC041699-1|AAH41699.1| 659|Homo sapiens armadillo repeat
containing 8 protein.
Length = 659
Score = 37.1 bits (82), Expect = 0.077
Identities = 35/192 (18%), Positives = 84/192 (43%), Gaps = 3/192 (1%)
Frame = +3
Query: 231 NAENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNPALQFETAWALT 410
NA + +A+ C LL + +P + ++ +G + +L L++++NPAL+ WAL
Sbjct: 423 NAPDEILVVASSMLCNLLL--EFSPSKEPILESGAVELLCG-LTQSENPALRVNGIWALM 479
Query: 411 NIASGTSAQTN-KVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELG 587
N+A + ++ + + +LL NV + + L N++ P + + G
Sbjct: 480 NMAFQAEQKIKADILRSLSTEQLFRLLSDSDLNVLMKTLGLLRNLLSTRPHIDKIMSTHG 539
Query: 588 --VVKPLLSLIKSDIPIPFLRNVTWVIVNLCRSKDPPPPLKTIQEILPALNVLILHNDSS 761
+++ + +++ + I ++ N+ + T +IL + + H+
Sbjct: 540 KQIMQAVTLILEGEHNIEVKEQTLCILANIADGTTAKDLIMTNDDILQKIKYYMGHSHVK 599
Query: 762 VLVDTVWAIXYL 797
+ + ++ I L
Sbjct: 600 LQLAAMFCISNL 611
>BC032661-1|AAH32661.1| 659|Homo sapiens armadillo repeat
containing 8 protein.
Length = 659
Score = 37.1 bits (82), Expect = 0.077
Identities = 35/192 (18%), Positives = 84/192 (43%), Gaps = 3/192 (1%)
Frame = +3
Query: 231 NAENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNPALQFETAWALT 410
NA + +A+ C LL + +P + ++ +G + +L L++++NPAL+ WAL
Sbjct: 423 NAPDEILVVASSMLCNLLL--EFSPSKEPILESGAVELLCG-LTQSENPALRVNGIWALM 479
Query: 411 NIASGTSAQTN-KVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELG 587
N+A + ++ + + +LL NV + + L N++ P + + G
Sbjct: 480 NMAFQAEQKIKADILRSLSTEQLFRLLSDSDLNVLMKTLGLLRNLLSTRPHIDKIMSTHG 539
Query: 588 --VVKPLLSLIKSDIPIPFLRNVTWVIVNLCRSKDPPPPLKTIQEILPALNVLILHNDSS 761
+++ + +++ + I ++ N+ + T +IL + + H+
Sbjct: 540 KQIMQAVTLILEGEHNIEVKEQTLCILANIADGTTAKDLIMTNDDILQKIKYYMGHSHVK 599
Query: 762 VLVDTVWAIXYL 797
+ + ++ I L
Sbjct: 600 LQLAAMFCISNL 611
>AL096748-1|CAB46423.1| 242|Homo sapiens hypothetical protein
protein.
Length = 242
Score = 37.1 bits (82), Expect = 0.077
Identities = 35/192 (18%), Positives = 84/192 (43%), Gaps = 3/192 (1%)
Frame = +3
Query: 231 NAENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNPALQFETAWALT 410
NA + +A+ C LL + +P + ++ +G + +L L++++NPAL+ WAL
Sbjct: 6 NAPDEILVVASSMLCNLLL--EFSPSKEPILESGAVELLCG-LTQSENPALRVNGIWALM 62
Query: 411 NIASGTSAQTN-KVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELG 587
N+A + ++ + + +LL NV + + L N++ P + + G
Sbjct: 63 NMAFQAEQKIKADILRSLSTEQLFRLLSDSDLNVLMKTLGLLRNLLSTRPHIDKIMSTHG 122
Query: 588 --VVKPLLSLIKSDIPIPFLRNVTWVIVNLCRSKDPPPPLKTIQEILPALNVLILHNDSS 761
+++ + +++ + I ++ N+ + T +IL + + H+
Sbjct: 123 KQIMQAVTLILEGEHNIEVKEQTLCILANIADGTTAKDLIMTNDDILQKIKYYMGHSHVK 182
Query: 762 VLVDTVWAIXYL 797
+ + ++ I L
Sbjct: 183 LQLAAMFCISNL 194
>BC014945-1|AAH14945.1| 771|Homo sapiens ARMC5 protein protein.
Length = 771
Score = 35.9 bits (79), Expect = 0.18
Identities = 24/79 (30%), Positives = 41/79 (51%)
Frame = +3
Query: 378 ALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGP 557
++Q TA AL N+A + + AGAVP+ ++ L + ++ C Q+V + D P
Sbjct: 5 SIQNRTARALGNLAMEPES-CGDIHCAGAVPLLVESLTACQDSQCLQSVVRALRNLADSP 63
Query: 558 VLRDFVIELGVVKPLLSLI 614
R + + G V+PL L+
Sbjct: 64 QHRLALAQQGAVRPLAELL 82
>AL513128-1|CAH72207.1| 246|Homo sapiens sperm associated antigen 6
protein.
Length = 246
Score = 35.9 bits (79), Expect = 0.18
Identities = 21/51 (41%), Positives = 27/51 (52%)
Frame = +3
Query: 318 LIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVP 470
++ G L LV CL D P ++ AWAL IA + + VV AGAVP
Sbjct: 197 IVDCGALDTLVICLEDFD-PGVKEAAAWALRYIARHNAELSQAVVDAGAVP 246
>AL158211-12|CAI15960.1| 246|Homo sapiens sperm associated antigen
6 protein.
Length = 246
Score = 35.9 bits (79), Expect = 0.18
Identities = 21/51 (41%), Positives = 27/51 (52%)
Frame = +3
Query: 318 LIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVP 470
++ G L LV CL D P ++ AWAL IA + + VV AGAVP
Sbjct: 197 IVDCGALDTLVICLEDFD-PGVKEAAAWALRYIARHNAELSQAVVDAGAVP 246
>AK023125-1|BAB14418.1| 502|Homo sapiens protein ( Homo sapiens
cDNA FLJ13063 fis, clone NT2RP3001678. ).
Length = 502
Score = 35.9 bits (79), Expect = 0.18
Identities = 24/79 (30%), Positives = 41/79 (51%)
Frame = +3
Query: 378 ALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGP 557
++Q TA AL N+A + + AGAVP+ ++ L + ++ C Q+V + D P
Sbjct: 5 SIQNRTARALGNLAMEPES-CGDIHCAGAVPLLVESLTACQDSQCLQSVVRALRNLADSP 63
Query: 558 VLRDFVIELGVVKPLLSLI 614
R + + G V+PL L+
Sbjct: 64 QHRLALAQQGAVRPLAELL 82
>AK001882-1|BAA91959.1| 431|Homo sapiens protein ( Homo sapiens
cDNA FLJ11020 fis, clone PLACE1003625, weakly similar to
ARMADILLO SEGMENT POLARITY PROTEIN. ).
Length = 431
Score = 35.1 bits (77), Expect = 0.31
Identities = 34/192 (17%), Positives = 84/192 (43%), Gaps = 3/192 (1%)
Frame = +3
Query: 231 NAENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNPALQFETAWALT 410
NA + +A+ C LL + +P + ++ +G + +L L++++NPAL+ WAL
Sbjct: 195 NAPDEILVVASSMLCNLLL--EFSPSKEPILESGAVELLCG-LTQSENPALRVNGIWALM 251
Query: 411 NIASGTSAQTN-KVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELG 587
N+A + ++ + + +LL NV + + L +++ P + + G
Sbjct: 252 NMAFQAEQKIKADILRSLSTEQLFRLLSDSDLNVLMKTLGLLRSLLSTRPHIDKIMSTHG 311
Query: 588 --VVKPLLSLIKSDIPIPFLRNVTWVIVNLCRSKDPPPPLKTIQEILPALNVLILHNDSS 761
+++ + +++ + I ++ N+ + T +IL + + H+
Sbjct: 312 KQIMQAVTLILEGEHNIEVKEQTLCILANIADGTTAKDLIMTNDDILQKIKYYMGHSHVK 371
Query: 762 VLVDTVWAIXYL 797
+ + ++ I L
Sbjct: 372 LQLAAMFCISNL 383
>BC011728-1|AAH11728.1| 198|Homo sapiens armadillo repeat
containing 7 protein.
Length = 198
Score = 33.5 bits (73), Expect = 0.94
Identities = 26/112 (23%), Positives = 50/112 (44%), Gaps = 1/112 (0%)
Frame = +3
Query: 333 ILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVC 512
+L + + LS + ++F L N+ A ++HAG VP+ + L SP+E
Sbjct: 58 VLDLFLDSLSEENETLVEFAIG-GLCNLCPDR-ANKEHILHAGGVPLIINCLSSPNEETV 115
Query: 513 DQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPF-LRNVTWVIV 665
A+ L ++ P R F+ EL + +++ + LRN+ + +
Sbjct: 116 LSAITTLMHL---SPPGRSFLPELTATPVVQCMLRFSLSASARLRNLAQIFL 164
>AL513128-2|CAH72208.1| 191|Homo sapiens sperm associated antigen 6
protein.
Length = 191
Score = 33.5 bits (73), Expect = 0.94
Identities = 22/72 (30%), Positives = 29/72 (40%), Gaps = 1/72 (1%)
Frame = +3
Query: 282 LLSCDKNPP-IDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHA 458
++ CD P + L +P L CLS ++ AWAL I T V
Sbjct: 79 VVKCDILPQLVYSLAEQNGVPQLSVCLSEEPEDHIKAAAAWALGQIGRHTPEHARAVAVT 138
Query: 459 GAVPVFLQLLMS 494
+PV L L MS
Sbjct: 139 NTLPVLLSLYMS 150
>AL158211-13|CAI15961.1| 191|Homo sapiens sperm associated antigen
6 protein.
Length = 191
Score = 33.5 bits (73), Expect = 0.94
Identities = 22/72 (30%), Positives = 29/72 (40%), Gaps = 1/72 (1%)
Frame = +3
Query: 282 LLSCDKNPP-IDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHA 458
++ CD P + L +P L CLS ++ AWAL I T V
Sbjct: 79 VVKCDILPQLVYSLAEQNGVPQLSVCLSEEPEDHIKAAAAWALGQIGRHTPEHARAVAVT 138
Query: 459 GAVPVFLQLLMS 494
+PV L L MS
Sbjct: 139 NTLPVLLSLYMS 150
>AK025813-1|BAB15242.1| 198|Homo sapiens protein ( Homo sapiens
cDNA: FLJ22160 fis, clone HRC00266. ).
Length = 198
Score = 33.5 bits (73), Expect = 0.94
Identities = 26/112 (23%), Positives = 50/112 (44%), Gaps = 1/112 (0%)
Frame = +3
Query: 333 ILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVC 512
+L + + LS + ++F L N+ A ++HAG VP+ + L SP+E
Sbjct: 58 VLDLFLDSLSEENETLVEFAIG-GLCNLCPDR-ANKEHILHAGGVPLIINCLSSPNEETV 115
Query: 513 DQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPF-LRNVTWVIV 665
A+ L ++ P R F+ EL + +++ + LRN+ + +
Sbjct: 116 LSAITTLMHL---SPPGRSFLPELTATPVVQCMLRFSLSASARLRNLAQIFL 164
>BC039312-1|AAH39312.1| 872|Homo sapiens armadillo repeat
containing 3 protein.
Length = 872
Score = 33.1 bits (72), Expect = 1.2
Identities = 17/52 (32%), Positives = 27/52 (51%)
Frame = +3
Query: 465 VPVFLQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIKS 620
+P +QLL S +E V + A AL N+ P + E + PL++L+ S
Sbjct: 358 IPQLIQLLKSDNEEVREAAALALANLTTCNPANANAAAEADGIDPLINLLSS 409
>AY436643-1|AAR99738.1| 688|Homo sapiens beta-catenin-like protein
protein.
Length = 688
Score = 33.1 bits (72), Expect = 1.2
Identities = 17/52 (32%), Positives = 27/52 (51%)
Frame = +3
Query: 465 VPVFLQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIKS 620
+P +QLL S +E V + A AL N+ P + E + PL++L+ S
Sbjct: 358 IPQLIQLLKSDNEEVREAAALALANLTTCNPANANAAAEADGIDPLINLLSS 409
>AL139815-2|CAH72189.1| 875|Homo sapiens novel protein protein.
Length = 875
Score = 33.1 bits (72), Expect = 1.2
Identities = 17/52 (32%), Positives = 27/52 (51%)
Frame = +3
Query: 465 VPVFLQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIKS 620
+P +QLL S +E V + A AL N+ P + E + PL++L+ S
Sbjct: 358 IPQLIQLLKSDNEEVREAAALALANLTTCNPANANAAAEADGIDPLINLLSS 409
>AL139815-1|CAH72188.1| 546|Homo sapiens novel protein protein.
Length = 546
Score = 33.1 bits (72), Expect = 1.2
Identities = 17/52 (32%), Positives = 27/52 (51%)
Frame = +3
Query: 465 VPVFLQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIKS 620
+P +QLL S +E V + A AL N+ P + E + PL++L+ S
Sbjct: 294 IPQLIQLLKSDNEEVREAAALALANLTTCNPANANAAAEADGIDPLINLLSS 345
>AK057389-1|BAB71463.1| 669|Homo sapiens protein ( Homo sapiens
cDNA FLJ32827 fis, clone TESTI2003109, weakly similar to
VACUOLAR PROTEIN 8. ).
Length = 669
Score = 33.1 bits (72), Expect = 1.2
Identities = 17/52 (32%), Positives = 27/52 (51%)
Frame = +3
Query: 465 VPVFLQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIKS 620
+P +QLL S +E V + A AL N+ P + E + PL++L+ S
Sbjct: 358 IPQLIQLLKSDNEEVREAAALALANLTTCNPANANAAAEADGIDPLINLLSS 409
>D50550-1|BAA19516.1| 1032|Homo sapiens LLGL protein.
Length = 1032
Score = 32.7 bits (71), Expect = 1.6
Identities = 21/62 (33%), Positives = 32/62 (51%), Gaps = 1/62 (1%)
Frame = +3
Query: 327 AGILP-ILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHE 503
AG LP +LVQCL A A+ T W+L +A GTS + PV + + P++
Sbjct: 585 AGFLPRVLVQCLPPAAVTAVTLHTEWSL--VAFGTSHGFGLFDYQRKSPVLARCTLHPND 642
Query: 504 NV 509
++
Sbjct: 643 SL 644
>Z83131-1|CAI42019.1| 632|Homo sapiens armadillo repeat containing,
X-linked 2 protein.
Length = 632
Score = 31.9 bits (69), Expect = 2.9
Identities = 20/92 (21%), Positives = 45/92 (48%), Gaps = 3/92 (3%)
Frame = +3
Query: 276 RKLLSCDKNP---PIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNK 446
R+ ++ K P IDE++ L ++ L ++D+P +Q L+N A+ S
Sbjct: 365 RRPVAMQKRPFPYEIDEILGVRDLRKVLALLQKSDDPFIQQVALLTLSNNAN-YSCNQET 423
Query: 447 VVHAGAVPVFLQLLMSPHENVCDQAVWALGNI 542
+ G +P+ ++ ++ ++A+ A+ N+
Sbjct: 424 IRKLGGLPIIANMINKTDPHIKEKALMAMNNL 455
>BC015926-1|AAH15926.1| 632|Homo sapiens ARMCX2 protein protein.
Length = 632
Score = 31.9 bits (69), Expect = 2.9
Identities = 20/92 (21%), Positives = 45/92 (48%), Gaps = 3/92 (3%)
Frame = +3
Query: 276 RKLLSCDKNP---PIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNK 446
R+ ++ K P IDE++ L ++ L ++D+P +Q L+N A+ S
Sbjct: 365 RRPVAMQKRPFPYEIDEILGVRDLRKVLALLQKSDDPFIQQVALLTLSNNAN-YSCNQET 423
Query: 447 VVHAGAVPVFLQLLMSPHENVCDQAVWALGNI 542
+ G +P+ ++ ++ ++A+ A+ N+
Sbjct: 424 IRKLGGLPIIANMINKTDPHIKEKALMAMNNL 455
>BC012541-1|AAH12541.1| 632|Homo sapiens armadillo repeat
containing, X-linked 2 protein.
Length = 632
Score = 31.9 bits (69), Expect = 2.9
Identities = 20/92 (21%), Positives = 45/92 (48%), Gaps = 3/92 (3%)
Frame = +3
Query: 276 RKLLSCDKNP---PIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNK 446
R+ ++ K P IDE++ L ++ L ++D+P +Q L+N A+ S
Sbjct: 365 RRPVAMQKRPFPYEIDEILGVRDLRKVLALLQKSDDPFIQQVALLTLSNNAN-YSCNQET 423
Query: 447 VVHAGAVPVFLQLLMSPHENVCDQAVWALGNI 542
+ G +P+ ++ ++ ++A+ A+ N+
Sbjct: 424 IRKLGGLPIIANMINKTDPHIKEKALMAMNNL 455
>AB011084-1|BAA25438.2| 710|Homo sapiens KIAA0512 protein protein.
Length = 710
Score = 31.9 bits (69), Expect = 2.9
Identities = 20/92 (21%), Positives = 45/92 (48%), Gaps = 3/92 (3%)
Frame = +3
Query: 276 RKLLSCDKNP---PIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNK 446
R+ ++ K P IDE++ L ++ L ++D+P +Q L+N A+ S
Sbjct: 443 RRPVAMQKRPFPYEIDEILGVRDLRKVLALLQKSDDPFIQQVALLTLSNNAN-YSCNQET 501
Query: 447 VVHAGAVPVFLQLLMSPHENVCDQAVWALGNI 542
+ G +P+ ++ ++ ++A+ A+ N+
Sbjct: 502 IRKLGGLPIIANMINKTDPHIKEKALMAMNNL 533
>BC132827-1|AAI32828.1| 949|Homo sapiens CCDC66 protein protein.
Length = 949
Score = 31.5 bits (68), Expect = 3.8
Identities = 23/82 (28%), Positives = 37/82 (45%)
Frame = +3
Query: 39 KNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPISYSTDEEEIDKNLATTDLDELV 218
K K ++E +R++ E ELR + E +QK+ I +EEI T +EL
Sbjct: 478 KRRKKQLEEEQRKKEEQEEELRLAQEREEMQKQYEEDILKQKQKEEI----MTLKTNELF 533
Query: 219 MNAANAENPEAQLAAVQQCRKL 284
A+ +L Q+ R+L
Sbjct: 534 QTMQRAQELAQRLKQEQRIREL 555
>BC047509-1|AAH47509.1| 831|Homo sapiens coiled-coil domain
containing 66 protein.
Length = 831
Score = 31.5 bits (68), Expect = 3.8
Identities = 23/82 (28%), Positives = 37/82 (45%)
Frame = +3
Query: 39 KNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPISYSTDEEEIDKNLATTDLDELV 218
K K ++E +R++ E ELR + E +QK+ I +EEI T +EL
Sbjct: 361 KRRKKQLEEEQRKKEEQEEELRLAQEREEMQKQYEEDILKQKQKEEI----MTLKTNELF 416
Query: 219 MNAANAENPEAQLAAVQQCRKL 284
A+ +L Q+ R+L
Sbjct: 417 QTMQRAQELAQRLKQEQRIREL 438
>BC009618-1|AAH09618.1| 253|Homo sapiens TMCO6 protein protein.
Length = 253
Score = 31.5 bits (68), Expect = 3.8
Identities = 16/74 (21%), Positives = 34/74 (45%)
Frame = +3
Query: 393 TAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGPVLRDF 572
T A+ + + +VV A+ + LQ ++ + +W L N+ + P
Sbjct: 80 TEAAVETVGGQMQLRDERVV--AALFILLQFFFQKQPSLLPEGLWLLNNLTANSPSFCTS 137
Query: 573 VIELGVVKPLLSLI 614
++ L +++PLL L+
Sbjct: 138 LLSLDLIEPLLQLL 151
>BC001910-1|AAH01910.1| 253|Homo sapiens TMCO6 protein protein.
Length = 253
Score = 31.5 bits (68), Expect = 3.8
Identities = 16/74 (21%), Positives = 34/74 (45%)
Frame = +3
Query: 393 TAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGPVLRDF 572
T A+ + + +VV A+ + LQ ++ + +W L N+ + P
Sbjct: 80 TEAAVETVGGQMQLRDERVV--AALFILLQFFFQKQPSLLPEGLWLLNNLTANSPSFCTS 137
Query: 573 VIELGVVKPLLSLI 614
++ L +++PLL L+
Sbjct: 138 LLSLDLIEPLLQLL 151
>AY376900-1|AAQ85126.1| 516|Homo sapiens GTP-GDP dissociation
stimulator 1 isoform A protein.
Length = 516
Score = 31.1 bits (67), Expect = 5.0
Identities = 32/131 (24%), Positives = 50/131 (38%), Gaps = 1/131 (0%)
Frame = +3
Query: 237 ENPEAQLAAVQQCRKLLSCDKNPPIDELI-AAGILPILVQCLSRADNPALQFETAWALTN 413
+ E L C N E I A+GIL + L+ + + + A +
Sbjct: 18 DKTEDSLEGCLDCLLQALAQNNTETSEKIQASGILQLFSSLLT--PQSSCKAKVANIIAE 75
Query: 414 IASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVV 593
+A + V AG + +QLL S + V Q ALGNI D ++ +
Sbjct: 76 VAKNEFMRI-PCVDAGLISPLVQLLNSKDQEVLLQTGRALGNICYDSQSSKEQFASTNIA 134
Query: 594 KPLLSLIKSDI 626
+ L+ L K I
Sbjct: 135 EELVKLFKKQI 145
>AL390866-5|CAI12711.1| 1044|Homo sapiens novel protein protein.
Length = 1044
Score = 31.1 bits (67), Expect = 5.0
Identities = 29/104 (27%), Positives = 52/104 (50%), Gaps = 4/104 (3%)
Frame = +3
Query: 465 VPVFLQLLMSPHENVCDQAVWAL----GNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPI 632
V + LL +PH +V A WAL N G ++R FV G ++ +++L+KSD
Sbjct: 840 VRLLWSLLKNPHPDVKASAAWALCPCIKNAKDAGEMVRSFV---GGLELIVNLLKSDNK- 895
Query: 633 PFLRNVTWVIVNLCRSKDPPPPLKTIQEILPALNVLILHNDSSV 764
L +V I N+ + ++ + T ++P L+ L N++ +
Sbjct: 896 EVLASVCAAITNIAKDQENLAVI-TDHGVVPLLSKLANTNNNKL 938
>AL355372-1|CAI16402.1| 1044|Homo sapiens novel protein protein.
Length = 1044
Score = 31.1 bits (67), Expect = 5.0
Identities = 29/104 (27%), Positives = 52/104 (50%), Gaps = 4/104 (3%)
Frame = +3
Query: 465 VPVFLQLLMSPHENVCDQAVWAL----GNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPI 632
V + LL +PH +V A WAL N G ++R FV G ++ +++L+KSD
Sbjct: 840 VRLLWSLLKNPHPDVKASAAWALCPCIKNAKDAGEMVRSFV---GGLELIVNLLKSDNK- 895
Query: 633 PFLRNVTWVIVNLCRSKDPPPPLKTIQEILPALNVLILHNDSSV 764
L +V I N+ + ++ + T ++P L+ L N++ +
Sbjct: 896 EVLASVCAAITNIAKDQENLAVI-TDHGVVPLLSKLANTNNNKL 938
>Z19054-1|CAA79497.1| 781|Homo sapiens beta catenin protein.
Length = 781
Score = 30.7 bits (66), Expect = 6.7
Identities = 21/62 (33%), Positives = 29/62 (46%), Gaps = 2/62 (3%)
Frame = +3
Query: 441 NKVVHAG--AVPVFLQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLI 614
N++V G +P+F+QLL SP EN+ A L + D E G PL L+
Sbjct: 586 NRIVIRGLNTIPLFVQLLYSPIENIQRVAAGVLCELAQDKEAAEAIEAE-GATAPLTELL 644
Query: 615 KS 620
S
Sbjct: 645 HS 646
>X87838-1|CAA61107.1| 781|Homo sapiens beta-catenin protein.
Length = 781
Score = 30.7 bits (66), Expect = 6.7
Identities = 21/62 (33%), Positives = 29/62 (46%), Gaps = 2/62 (3%)
Frame = +3
Query: 441 NKVVHAG--AVPVFLQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLI 614
N++V G +P+F+QLL SP EN+ A L + D E G PL L+
Sbjct: 586 NRIVIRGLNTIPLFVQLLYSPIENIQRVAAGVLCELAQDKEAAEAIEAE-GATAPLTELL 644
Query: 615 KS 620
S
Sbjct: 645 HS 646
>X07290-1|CAA30269.1| 195|Homo sapiens protein ( Human HF.12 gene
mRNA. ).
Length = 195
Score = 30.7 bits (66), Expect = 6.7
Identities = 21/65 (32%), Positives = 28/65 (43%), Gaps = 4/65 (6%)
Frame = +2
Query: 572 CDRTRSCQTTTELNQIRHTNPIPQECNMGDCQPLQE*RSTTTSEN--HPGDT--ACPKCS 739
C +T SC + L++ HT P ECN +C ST T H G+ AC +C
Sbjct: 10 CGKTFSCSSALILHRRIHTGEKPYECN--ECGKTFSWSSTLTHHQRIHTGEKPYACNECG 67
Query: 740 NPTQR 754
R
Sbjct: 68 KAFSR 72
>U72069-1|AAB58254.1| 890|Homo sapiens karyopherin beta2 protein.
Length = 890
Score = 30.7 bits (66), Expect = 6.7
Identities = 22/79 (27%), Positives = 39/79 (49%), Gaps = 1/79 (1%)
Frame = +3
Query: 309 IDELIA-AGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQL 485
I++L+A + IL ++ QC+ D ++++AL + Q K A +P+
Sbjct: 659 IEQLVARSNILTLMYQCMQ--DKMPEVRQSSFALLGDLTKACFQHVKPCIADFMPILGTN 716
Query: 486 LMSPHENVCDQAVWALGNI 542
L +VC+ A WA+G I
Sbjct: 717 LNPEFISVCNNATWAIGEI 735
>U70322-1|AAC50723.1| 890|Homo sapiens transportin protein.
Length = 890
Score = 30.7 bits (66), Expect = 6.7
Identities = 22/79 (27%), Positives = 39/79 (49%), Gaps = 1/79 (1%)
Frame = +3
Query: 309 IDELIA-AGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQL 485
I++L+A + IL ++ QC+ D ++++AL + Q K A +P+
Sbjct: 659 IEQLVARSNILTLMYQCMQ--DKMPEVRQSSFALLGDLTKACFQHVKPCIADFMPILGTN 716
Query: 486 LMSPHENVCDQAVWALGNI 542
L +VC+ A WA+G I
Sbjct: 717 LNPEFISVCNNATWAIGEI 735
>BT006918-1|AAP35564.1| 410|Homo sapiens zinc finger protein 3
(A8-51) protein.
Length = 410
Score = 30.7 bits (66), Expect = 6.7
Identities = 21/65 (32%), Positives = 28/65 (43%), Gaps = 4/65 (6%)
Frame = +2
Query: 572 CDRTRSCQTTTELNQIRHTNPIPQECNMGDCQPLQE*RSTTTSEN--HPGDT--ACPKCS 739
C +T SC + L++ HT P ECN +C ST T H G+ AC +C
Sbjct: 225 CGKTFSCSSALILHRRIHTGEKPYECN--ECGKTFSWSSTLTHHQRIHTGEKPYACNECG 282
Query: 740 NPTQR 754
R
Sbjct: 283 KAFSR 287
>BC058926-1|AAH58926.1| 781|Homo sapiens catenin
(cadherin-associated protein), beta 1, 88kDa protein.
Length = 781
Score = 30.7 bits (66), Expect = 6.7
Identities = 21/62 (33%), Positives = 29/62 (46%), Gaps = 2/62 (3%)
Frame = +3
Query: 441 NKVVHAG--AVPVFLQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLI 614
N++V G +P+F+QLL SP EN+ A L + D E G PL L+
Sbjct: 586 NRIVIRGLNTIPLFVQLLYSPIENIQRVAAGVLCELAQDKEAAEAIEAE-GATAPLTELL 644
Query: 615 KS 620
S
Sbjct: 645 HS 646
>BC040340-1|AAH40340.1| 890|Homo sapiens transportin 1 protein.
Length = 890
Score = 30.7 bits (66), Expect = 6.7
Identities = 22/79 (27%), Positives = 39/79 (49%), Gaps = 1/79 (1%)
Frame = +3
Query: 309 IDELIA-AGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQL 485
I++L+A + IL ++ QC+ D ++++AL + Q K A +P+
Sbjct: 659 IEQLVARSNILTLMYQCMQ--DKMPEVRQSSFALLGDLTKACFQHVKPCIADFMPILGTN 716
Query: 486 LMSPHENVCDQAVWALGNI 542
L +VC+ A WA+G I
Sbjct: 717 LNPEFISVCNNATWAIGEI 735
>BC025265-1|AAH25265.1| 410|Homo sapiens ZNF3 protein protein.
Length = 410
Score = 30.7 bits (66), Expect = 6.7
Identities = 21/65 (32%), Positives = 28/65 (43%), Gaps = 4/65 (6%)
Frame = +2
Query: 572 CDRTRSCQTTTELNQIRHTNPIPQECNMGDCQPLQE*RSTTTSEN--HPGDT--ACPKCS 739
C +T SC + L++ HT P ECN +C ST T H G+ AC +C
Sbjct: 225 CGKTFSCSSALILHRRIHTGEKPYECN--ECGKTFSWSSTLTHHQRIHTGEKPYACNECG 282
Query: 740 NPTQR 754
R
Sbjct: 283 KAFSR 287
>BC013603-1|AAH13603.1| 410|Homo sapiens ZNF3 protein protein.
Length = 410
Score = 30.7 bits (66), Expect = 6.7
Identities = 21/65 (32%), Positives = 28/65 (43%), Gaps = 4/65 (6%)
Frame = +2
Query: 572 CDRTRSCQTTTELNQIRHTNPIPQECNMGDCQPLQE*RSTTTSEN--HPGDT--ACPKCS 739
C +T SC + L++ HT P ECN +C ST T H G+ AC +C
Sbjct: 225 CGKTFSCSSALILHRRIHTGEKPYECN--ECGKTFSWSSTLTHHQRIHTGEKPYACNECG 282
Query: 740 NPTQR 754
R
Sbjct: 283 KAFSR 287
>BC011887-1|AAH11887.2| 446|Homo sapiens zinc finger protein 3
protein.
Length = 446
Score = 30.7 bits (66), Expect = 6.7
Identities = 21/65 (32%), Positives = 28/65 (43%), Gaps = 4/65 (6%)
Frame = +2
Query: 572 CDRTRSCQTTTELNQIRHTNPIPQECNMGDCQPLQE*RSTTTSEN--HPGDT--ACPKCS 739
C +T SC + L++ HT P ECN +C ST T H G+ AC +C
Sbjct: 261 CGKTFSCSSALILHRRIHTGEKPYECN--ECGKTFSWSSTLTHHQRIHTGEKPYACNECG 318
Query: 740 NPTQR 754
R
Sbjct: 319 KAFSR 323
>AY463360-1|AAR18817.1| 781|Homo sapiens catenin
(cadherin-associated protein), beta 1, 88kDa protein.
Length = 781
Score = 30.7 bits (66), Expect = 6.7
Identities = 21/62 (33%), Positives = 29/62 (46%), Gaps = 2/62 (3%)
Frame = +3
Query: 441 NKVVHAG--AVPVFLQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLI 614
N++V G +P+F+QLL SP EN+ A L + D E G PL L+
Sbjct: 586 NRIVIRGLNTIPLFVQLLYSPIENIQRVAAGVLCELAQDKEAAEAIEAE-GATAPLTELL 644
Query: 615 KS 620
S
Sbjct: 645 HS 646
>AK000223-1|BAA91019.1| 387|Homo sapiens protein ( Homo sapiens
cDNA FLJ20216 fis, clone COLF3242. ).
Length = 387
Score = 30.7 bits (66), Expect = 6.7
Identities = 21/65 (32%), Positives = 28/65 (43%), Gaps = 4/65 (6%)
Frame = +2
Query: 572 CDRTRSCQTTTELNQIRHTNPIPQECNMGDCQPLQE*RSTTTSEN--HPGDT--ACPKCS 739
C +T SC + L++ HT P ECN +C ST T H G+ AC +C
Sbjct: 261 CGKTFSCSSALILHRRIHTGEKPYECN--ECGKTFSWSSTLTHHQRIHTGEKPYACNECG 318
Query: 740 NPTQR 754
R
Sbjct: 319 KAFSR 323
>AB062292-1|BAB93475.1| 511|Homo sapiens catenin beta 1 protein.
Length = 511
Score = 30.7 bits (66), Expect = 6.7
Identities = 21/62 (33%), Positives = 29/62 (46%), Gaps = 2/62 (3%)
Frame = +3
Query: 441 NKVVHAG--AVPVFLQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLI 614
N++V G +P+F+QLL SP EN+ A L + D E G PL L+
Sbjct: 316 NRIVIRGLNTIPLFVQLLYSPIENIQRVAAGVLCELAQDKEAAEAIEAE-GATAPLTELL 374
Query: 615 KS 620
S
Sbjct: 375 HS 376
>Z73678-1|CAA98022.1| 726|Homo sapiens plakophilin 1 protein.
Length = 726
Score = 30.3 bits (65), Expect = 8.8
Identities = 31/141 (21%), Positives = 61/141 (43%), Gaps = 1/141 (0%)
Frame = +3
Query: 312 DELIAAGI-LPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLL 488
+++ +G+ +P VQ LS D Q A+ + + + +V G + + LL
Sbjct: 238 EDIECSGLTIPKAVQYLSSQDEK-YQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLL 296
Query: 489 MSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTWVIVN 668
SP++NV A AL N++ + ++ +SL++ + +T ++ N
Sbjct: 297 RSPNQNVQQAAAGALRNLVFRSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWN 356
Query: 669 LCRSKDPPPPLKTIQEILPAL 731
L + + L I + LP L
Sbjct: 357 LSSTDELKEEL--IADALPVL 375
>Z34974-1|CAA84426.1| 726|Homo sapiens plakophilin protein.
Length = 726
Score = 30.3 bits (65), Expect = 8.8
Identities = 31/141 (21%), Positives = 61/141 (43%), Gaps = 1/141 (0%)
Frame = +3
Query: 312 DELIAAGI-LPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLL 488
+++ +G+ +P VQ LS D Q A+ + + + +V G + + LL
Sbjct: 238 EDIECSGLTIPKAVQYLSSQDEK-YQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLL 296
Query: 489 MSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTWVIVN 668
SP++NV A AL N++ + ++ +SL++ + +T ++ N
Sbjct: 297 RSPNQNVQQAAAGALRNLVFRSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWN 356
Query: 669 LCRSKDPPPPLKTIQEILPAL 731
L + + L I + LP L
Sbjct: 357 LSSTDELKEEL--IADALPVL 375
>X79293-1|CAA55881.1| 725|Homo sapiens band-6-protein protein.
Length = 725
Score = 30.3 bits (65), Expect = 8.8
Identities = 31/141 (21%), Positives = 61/141 (43%), Gaps = 1/141 (0%)
Frame = +3
Query: 312 DELIAAGI-LPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLL 488
+++ +G+ +P VQ LS D Q A+ + + + +V G + + LL
Sbjct: 237 EDIECSGLTIPKAVQYLSSQDEK-YQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLL 295
Query: 489 MSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTWVIVN 668
SP++NV A AL N++ + ++ +SL++ + +T ++ N
Sbjct: 296 RSPNQNVQQAAAGALRNLVFRSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWN 355
Query: 669 LCRSKDPPPPLKTIQEILPAL 731
L + + L I + LP L
Sbjct: 356 LSSTDELKEEL--IADALPVL 374
>BC117686-1|AAI17687.1| 1683|Homo sapiens SHPRH protein protein.
Length = 1683
Score = 30.3 bits (65), Expect = 8.8
Identities = 29/114 (25%), Positives = 53/114 (46%), Gaps = 4/114 (3%)
Frame = +3
Query: 72 RRRNEVTVELRKNKREETL----QKRRNVPISYSTDEEEIDKNLATTDLDELVMNAANAE 239
RR+ V + + KR++ + RRN PI S D+E+ T+ ++++ + E
Sbjct: 4 RRKRAPPVRVDEEKRQQLHWNMHEDRRNEPIIISDDDEQPCPGSDTSSAHYIILSDSLKE 63
Query: 240 NPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNPALQFETAW 401
E ++C K++S K PI++ GI L L+ +P F+ +W
Sbjct: 64 --EVAHRDKKRCSKVVSFSK--PIEKEETVGIFSPLSVKLNIVISP-YHFDNSW 112
>BC117685-1|AAI17686.1| 155|Homo sapiens SHPRH protein protein.
Length = 155
Score = 30.3 bits (65), Expect = 8.8
Identities = 29/114 (25%), Positives = 53/114 (46%), Gaps = 4/114 (3%)
Frame = +3
Query: 72 RRRNEVTVELRKNKREETL----QKRRNVPISYSTDEEEIDKNLATTDLDELVMNAANAE 239
RR+ V + + KR++ + RRN PI S D+E+ T+ ++++ + E
Sbjct: 4 RRKRAPPVRVDEEKRQQLHWNMHEDRRNEPIIISDDDEQPCPGSDTSSAHYIILSDSLKE 63
Query: 240 NPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNPALQFETAW 401
E ++C K++S K PI++ GI L L+ +P F+ +W
Sbjct: 64 --EVAHRDKKRCSKVVSFSK--PIEKEETVGIFSPLSVKLNIVISP-YHFDNSW 112
>BC114571-1|AAI14572.1| 726|Homo sapiens plakophilin 1 (ectodermal
dysplasia/skin fragility syndrome) protein.
Length = 726
Score = 30.3 bits (65), Expect = 8.8
Identities = 31/141 (21%), Positives = 61/141 (43%), Gaps = 1/141 (0%)
Frame = +3
Query: 312 DELIAAGI-LPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLL 488
+++ +G+ +P VQ LS D Q A+ + + + +V G + + LL
Sbjct: 238 EDIECSGLTIPKAVQYLSSQDEK-YQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLL 296
Query: 489 MSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTWVIVN 668
SP++NV A AL N++ + ++ +SL++ + +T ++ N
Sbjct: 297 RSPNQNVQQAAAGALRNLVFRSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWN 356
Query: 669 LCRSKDPPPPLKTIQEILPAL 731
L + + L I + LP L
Sbjct: 357 LSSTDELKEEL--IADALPVL 375
>BC113089-1|AAI13090.1| 155|Homo sapiens SHPRH protein protein.
Length = 155
Score = 30.3 bits (65), Expect = 8.8
Identities = 29/114 (25%), Positives = 53/114 (46%), Gaps = 4/114 (3%)
Frame = +3
Query: 72 RRRNEVTVELRKNKREETL----QKRRNVPISYSTDEEEIDKNLATTDLDELVMNAANAE 239
RR+ V + + KR++ + RRN PI S D+E+ T+ ++++ + E
Sbjct: 4 RRKRAPPVRVDEEKRQQLHWNMHEDRRNEPIIISDDDEQPCPGSDTSSAHYIILSDSLKE 63
Query: 240 NPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNPALQFETAW 401
E ++C K++S K PI++ GI L L+ +P F+ +W
Sbjct: 64 --EVAHRDKKRCSKVVSFSK--PIEKEETVGIFSPLSVKLNIVISP-YHFDNSW 112
>BC026158-1|AAH26158.1| 1315|Homo sapiens serine/threonine kinase 36,
fused homolog (Drosophila) protein.
Length = 1315
Score = 30.3 bits (65), Expect = 8.8
Identities = 41/147 (27%), Positives = 65/147 (44%), Gaps = 3/147 (2%)
Frame = +3
Query: 327 AGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHEN 506
+G+L +L+ L D P ++ ++A+ N A + A AVP QLL P
Sbjct: 1151 SGLLSLLLLGLGDKD-PVVRCSASFAVGNAAYQAGPLGPAL--AAAVPSMTQLLGDPQAG 1207
Query: 507 VCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTWVIVNLCRSKD 686
+ ALGN+ +G L + +++ V + LL + D P P NV + RS
Sbjct: 1208 IRRNVASALGNLGPEG--LGEELLQCEVPQRLLEMACGD-PQP---NVKEAALIALRSLQ 1261
Query: 687 PPPPLKTIQEILPA---LNVLILHNDS 758
P + + L A L++L L N S
Sbjct: 1262 QEPGIHQVLVSLGASEKLSLLSLGNQS 1288
>AY163808-1|AAO06907.1| 1659|Homo sapiens helicase-like protein
protein.
Length = 1659
Score = 30.3 bits (65), Expect = 8.8
Identities = 29/114 (25%), Positives = 53/114 (46%), Gaps = 4/114 (3%)
Frame = +3
Query: 72 RRRNEVTVELRKNKREETL----QKRRNVPISYSTDEEEIDKNLATTDLDELVMNAANAE 239
RR+ V + + KR++ + RRN PI S D+E+ T+ ++++ + E
Sbjct: 4 RRKRAPPVRVDEEKRQQLHWNMHEDRRNEPIIISDDDEQPCPGSDTSSAHYIILSDSLKE 63
Query: 240 NPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNPALQFETAW 401
E ++C K++S K PI++ GI L L+ +P F+ +W
Sbjct: 64 --EVAHRDKKRCSKVVSFSK--PIEKEETVGIFSPLSVKLNIVISP-YHFDNSW 112
>AY161136-1|AAO26201.1| 1683|Homo sapiens SNF2 histone linker PHD
RING helicase protein.
Length = 1683
Score = 30.3 bits (65), Expect = 8.8
Identities = 29/114 (25%), Positives = 53/114 (46%), Gaps = 4/114 (3%)
Frame = +3
Query: 72 RRRNEVTVELRKNKREETL----QKRRNVPISYSTDEEEIDKNLATTDLDELVMNAANAE 239
RR+ V + + KR++ + RRN PI S D+E+ T+ ++++ + E
Sbjct: 4 RRKRAPPVRVDEEKRQQLHWNMHEDRRNEPIIISDDDEQPCPGSDTSSAHYIILSDSLKE 63
Query: 240 NPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNPALQFETAW 401
E ++C K++S K PI++ GI L L+ +P F+ +W
Sbjct: 64 --EVAHRDKKRCSKVVSFSK--PIEKEETVGIFSPLSVKLNIVISP-YHFDNSW 112
>AL451145-1|CAH70765.1| 1683|Homo sapiens SNF2 histone linker PHD
RING helicase protein.
Length = 1683
Score = 30.3 bits (65), Expect = 8.8
Identities = 29/114 (25%), Positives = 53/114 (46%), Gaps = 4/114 (3%)
Frame = +3
Query: 72 RRRNEVTVELRKNKREETL----QKRRNVPISYSTDEEEIDKNLATTDLDELVMNAANAE 239
RR+ V + + KR++ + RRN PI S D+E+ T+ ++++ + E
Sbjct: 4 RRKRAPPVRVDEEKRQQLHWNMHEDRRNEPIIISDDDEQPCPGSDTSSAHYIILSDSLKE 63
Query: 240 NPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNPALQFETAW 401
E ++C K++S K PI++ GI L L+ +P F+ +W
Sbjct: 64 --EVAHRDKKRCSKVVSFSK--PIEKEETVGIFSPLSVKLNIVISP-YHFDNSW 112
>AL356599-2|CAI41120.1| 1683|Homo sapiens SNF2 histone linker PHD
RING helicase protein.
Length = 1683
Score = 30.3 bits (65), Expect = 8.8
Identities = 29/114 (25%), Positives = 53/114 (46%), Gaps = 4/114 (3%)
Frame = +3
Query: 72 RRRNEVTVELRKNKREETL----QKRRNVPISYSTDEEEIDKNLATTDLDELVMNAANAE 239
RR+ V + + KR++ + RRN PI S D+E+ T+ ++++ + E
Sbjct: 4 RRKRAPPVRVDEEKRQQLHWNMHEDRRNEPIIISDDDEQPCPGSDTSSAHYIILSDSLKE 63
Query: 240 NPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNPALQFETAW 401
E ++C K++S K PI++ GI L L+ +P F+ +W
Sbjct: 64 --EVAHRDKKRCSKVVSFSK--PIEKEETVGIFSPLSVKLNIVISP-YHFDNSW 112
>AK075318-1|BAC11544.1| 584|Homo sapiens protein ( Homo sapiens
cDNA FLJ90837 fis, clone Y79AA1002121, weakly similar to
HISTONE H1. ).
Length = 584
Score = 30.3 bits (65), Expect = 8.8
Identities = 29/114 (25%), Positives = 53/114 (46%), Gaps = 4/114 (3%)
Frame = +3
Query: 72 RRRNEVTVELRKNKREETL----QKRRNVPISYSTDEEEIDKNLATTDLDELVMNAANAE 239
RR+ V + + KR++ + RRN PI S D+E+ T+ ++++ + E
Sbjct: 4 RRKRAPPVRVDEEKRQQLHWNMHEDRRNEPIIISDDDEQPCPGSDTSSAHYIILSDSLKE 63
Query: 240 NPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNPALQFETAW 401
E ++C K++S K PI++ GI L L+ +P F+ +W
Sbjct: 64 --EVAHRDKKRCSKVVSFSK--PIEKEETVGIFSPLSVKLNIVISP-YHFDNSW 112
>AK022692-1|BAB14184.1| 360|Homo sapiens protein ( Homo sapiens
cDNA FLJ12630 fis, clone NT2RM4001836. ).
Length = 360
Score = 30.3 bits (65), Expect = 8.8
Identities = 41/147 (27%), Positives = 65/147 (44%), Gaps = 3/147 (2%)
Frame = +3
Query: 327 AGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHEN 506
+G+L +L+ L D P ++ ++A+ N A + A AVP QLL P
Sbjct: 196 SGLLSLLLLGLGDKD-PVVRCSASFAVGNAAYQAGPLGPAL--AAAVPSMTQLLGDPQAG 252
Query: 507 VCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTWVIVNLCRSKD 686
+ ALGN+ +G L + +++ V + LL + D P P NV + RS
Sbjct: 253 IRRNVASALGNLGPEG--LGEELLQCEVPQRLLEMACGD-PQP---NVKEAALIALRSLQ 306
Query: 687 PPPPLKTIQEILPA---LNVLILHNDS 758
P + + L A L++L L N S
Sbjct: 307 QEPGIHQVLVSLGASEKLSLLSLGNQS 333
>AF200815-1|AAF97028.1| 1315|Homo sapiens FUSED serine/threonine
kinase protein.
Length = 1315
Score = 30.3 bits (65), Expect = 8.8
Identities = 41/147 (27%), Positives = 65/147 (44%), Gaps = 3/147 (2%)
Frame = +3
Query: 327 AGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHEN 506
+G+L +L+ L D P ++ ++A+ N A + A AVP QLL P
Sbjct: 1151 SGLLSLLLLGLGDKD-PVVRCSASFAVGNAAYQAGPLGPAL--AAAVPSMTQLLGDPQAG 1207
Query: 507 VCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTWVIVNLCRSKD 686
+ ALGN+ +G L + +++ V + LL + D P P NV + RS
Sbjct: 1208 IRRNVASALGNLGPEG--LGEELLQCEVPQRLLEMACGD-PQP---NVKEAALIALRSLQ 1261
Query: 687 PPPPLKTIQEILPA---LNVLILHNDS 758
P + + L A L++L L N S
Sbjct: 1262 QEPGIHQVLVSLGASEKLSLLSLGNQS 1288
>AB033104-1|BAA86592.1| 1311|Homo sapiens KIAA1278 protein protein.
Length = 1311
Score = 30.3 bits (65), Expect = 8.8
Identities = 41/147 (27%), Positives = 65/147 (44%), Gaps = 3/147 (2%)
Frame = +3
Query: 327 AGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHEN 506
+G+L +L+ L D P ++ ++A+ N A + A AVP QLL P
Sbjct: 1147 SGLLSLLLLGLGDKD-PVVRCSASFAVGNAAYQAGPLGPAL--AAAVPSMTQLLGDPQAG 1203
Query: 507 VCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTWVIVNLCRSKD 686
+ ALGN+ +G L + +++ V + LL + D P P NV + RS
Sbjct: 1204 IRRNVASALGNLGPEG--LGEELLQCEVPQRLLEMACGD-PQP---NVKEAALIALRSLQ 1257
Query: 687 PPPPLKTIQEILPA---LNVLILHNDS 758
P + + L A L++L L N S
Sbjct: 1258 QEPGIHQVLVSLGASEKLSLLSLGNQS 1284
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 124,589,073
Number of Sequences: 237096
Number of extensions: 2899335
Number of successful extensions: 8543
Number of sequences better than 10.0: 110
Number of HSP's better than 10.0 without gapping: 7312
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 8370
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 10259383312
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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