Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P11_F_I17
(844 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC052966-1|AAH52966.1| 976|Homo sapiens PARG protein protein. 130 5e-30
BC050560-1|AAH50560.1| 976|Homo sapiens poly (ADP-ribose) glyco... 130 5e-30
AY575849-1|AAT66422.1| 868|Homo sapiens poly (ADP-ribose) glyco... 130 5e-30
AY575848-1|AAT66421.1| 894|Homo sapiens poly (ADP-ribose) glyco... 130 5e-30
AY258587-1|AAP83314.1| 976|Homo sapiens poly(ADP-ribose) glycoh... 130 5e-30
AF005043-1|AAB61614.1| 976|Homo sapiens poly(ADP-ribose) glycoh... 130 5e-30
DQ867088-1|ABH85399.1| 976|Homo sapiens poly (ADP-ribose) glyco... 128 3e-29
AL731572-3|CAI15135.1| 491|Homo sapiens poly (ADP-ribose) glyco... 108 2e-23
EF382674-1|ABR10027.1| 527|Homo sapiens poly(ADP-ribose) glycoh... 71 4e-16
EF107108-1|ABK81123.1| 761|Homo sapiens sphingosine kinase-2 va... 31 5.2
BC010671-1|AAH10671.1| 618|Homo sapiens SPHK2 protein protein. 31 5.2
BC006161-1|AAH06161.1| 654|Homo sapiens sphingosine kinase 2 pr... 31 5.2
AK000599-1|BAA91280.1| 354|Homo sapiens protein ( Homo sapiens ... 31 5.2
AF245447-1|AAF74124.1| 618|Homo sapiens sphingosine kinase type... 31 5.2
CR457001-1|CAG33282.1| 273|Homo sapiens HSU79274 protein. 30 9.1
BC020967-1|AAH20967.1| 273|Homo sapiens chromosome 12 open read... 30 9.1
>BC052966-1|AAH52966.1| 976|Homo sapiens PARG protein protein.
Length = 976
Score = 130 bits (315), Expect = 5e-30
Identities = 74/210 (35%), Positives = 102/210 (48%), Gaps = 1/210 (0%)
Frame = +1
Query: 193 KKVIKLCTTMSTVTKNWLGVPISEIRGSQSPWGAPEFPLVVPAYNHSVLYHVQNGRPIDG 372
+K+ K + K WLG PI E+R + P PL+ P+ NH+V V R G
Sbjct: 437 RKIPKYVPPHLSPDKKWLGTPIEEMR--RMPRCGIRLPLLRPSANHTVTIRVDLLRA--G 492
Query: 373 DRP-PKPQIGRDKWDHEFVRMPCSNQSLYPFEDSNGDCHLKKRWEVIESSLWKPIRDSRE 549
+ P P P +D WD++ V+MPCS Q+LYP ED NG+ RWE+I+++L +
Sbjct: 493 EVPKPFPTHYKDLWDNKHVKMPCSEQNLYPVEDENGERTAGSRWELIQTALLNKFTRPQN 552
Query: 550 LANTILSYNTKFKKIWKFKALHKLFSEYLDEEETQYFFDVTXXXXXXXXXXXXXXXQSPI 729
L + IL YN + K W F AL + + L+E E Q+ + PI
Sbjct: 553 LKDAILKYNVAYSKKWDFTALIDFWDKVLEEAEAQHLYQSILPDMVKIALCLPNICTQPI 612
Query: 730 PLLKQHKNYXXXXXXXXXXXXXANAFFCTF 819
PLLKQ N+ ANAFFCTF
Sbjct: 613 PLLKQKMNHSITMSQEQIASLLANAFFCTF 642
>BC050560-1|AAH50560.1| 976|Homo sapiens poly (ADP-ribose)
glycohydrolase protein.
Length = 976
Score = 130 bits (315), Expect = 5e-30
Identities = 74/210 (35%), Positives = 102/210 (48%), Gaps = 1/210 (0%)
Frame = +1
Query: 193 KKVIKLCTTMSTVTKNWLGVPISEIRGSQSPWGAPEFPLVVPAYNHSVLYHVQNGRPIDG 372
+K+ K + K WLG PI E+R + P PL+ P+ NH+V V R G
Sbjct: 437 RKIPKYVPPHLSPDKKWLGTPIEEMR--RMPRCGIRLPLLRPSANHTVTIRVDLLRA--G 492
Query: 373 DRP-PKPQIGRDKWDHEFVRMPCSNQSLYPFEDSNGDCHLKKRWEVIESSLWKPIRDSRE 549
+ P P P +D WD++ V+MPCS Q+LYP ED NG+ RWE+I+++L +
Sbjct: 493 EVPKPFPTHYKDLWDNKHVKMPCSEQNLYPVEDENGERTAGSRWELIQTALLNKFTRPQN 552
Query: 550 LANTILSYNTKFKKIWKFKALHKLFSEYLDEEETQYFFDVTXXXXXXXXXXXXXXXQSPI 729
L + IL YN + K W F AL + + L+E E Q+ + PI
Sbjct: 553 LKDAILKYNVAYSKKWDFTALIDFWDKVLEEAEAQHLYQSILPDMVKIALCLPNICTQPI 612
Query: 730 PLLKQHKNYXXXXXXXXXXXXXANAFFCTF 819
PLLKQ N+ ANAFFCTF
Sbjct: 613 PLLKQKMNHSITMSQEQIASLLANAFFCTF 642
>AY575849-1|AAT66422.1| 868|Homo sapiens poly (ADP-ribose)
glycohydrolase protein.
Length = 868
Score = 130 bits (315), Expect = 5e-30
Identities = 74/210 (35%), Positives = 102/210 (48%), Gaps = 1/210 (0%)
Frame = +1
Query: 193 KKVIKLCTTMSTVTKNWLGVPISEIRGSQSPWGAPEFPLVVPAYNHSVLYHVQNGRPIDG 372
+K+ K + K WLG PI E+R + P PL+ P+ NH+V V R G
Sbjct: 329 RKIPKYVPPHLSPDKKWLGTPIEEMR--RMPRCGIRLPLLRPSANHTVTIRVDLLRA--G 384
Query: 373 DRP-PKPQIGRDKWDHEFVRMPCSNQSLYPFEDSNGDCHLKKRWEVIESSLWKPIRDSRE 549
+ P P P +D WD++ V+MPCS Q+LYP ED NG+ RWE+I+++L +
Sbjct: 385 EVPKPFPTHYKDLWDNKHVKMPCSEQNLYPVEDENGERTAGSRWELIQTALLNKFTRPQN 444
Query: 550 LANTILSYNTKFKKIWKFKALHKLFSEYLDEEETQYFFDVTXXXXXXXXXXXXXXXQSPI 729
L + IL YN + K W F AL + + L+E E Q+ + PI
Sbjct: 445 LKDAILKYNVAYSKKWDFTALIDFWDKVLEEAEAQHLYQSILPDMVKIALCLPNICTQPI 504
Query: 730 PLLKQHKNYXXXXXXXXXXXXXANAFFCTF 819
PLLKQ N+ ANAFFCTF
Sbjct: 505 PLLKQKMNHSITMSQEQIASLLANAFFCTF 534
>AY575848-1|AAT66421.1| 894|Homo sapiens poly (ADP-ribose)
glycohydrolase protein.
Length = 894
Score = 130 bits (315), Expect = 5e-30
Identities = 74/210 (35%), Positives = 102/210 (48%), Gaps = 1/210 (0%)
Frame = +1
Query: 193 KKVIKLCTTMSTVTKNWLGVPISEIRGSQSPWGAPEFPLVVPAYNHSVLYHVQNGRPIDG 372
+K+ K + K WLG PI E+R + P PL+ P+ NH+V V R G
Sbjct: 355 RKIPKYVPPHLSPDKKWLGTPIEEMR--RMPRCGIRLPLLRPSANHTVTIRVDLLRA--G 410
Query: 373 DRP-PKPQIGRDKWDHEFVRMPCSNQSLYPFEDSNGDCHLKKRWEVIESSLWKPIRDSRE 549
+ P P P +D WD++ V+MPCS Q+LYP ED NG+ RWE+I+++L +
Sbjct: 411 EVPKPFPTHYKDLWDNKHVKMPCSEQNLYPVEDENGERTAGSRWELIQTALLNKFTRPQN 470
Query: 550 LANTILSYNTKFKKIWKFKALHKLFSEYLDEEETQYFFDVTXXXXXXXXXXXXXXXQSPI 729
L + IL YN + K W F AL + + L+E E Q+ + PI
Sbjct: 471 LKDAILKYNVAYSKKWDFTALIDFWDKVLEEAEAQHLYQSILPDMVKIALCLPNICTQPI 530
Query: 730 PLLKQHKNYXXXXXXXXXXXXXANAFFCTF 819
PLLKQ N+ ANAFFCTF
Sbjct: 531 PLLKQKMNHSITMSQEQIASLLANAFFCTF 560
>AY258587-1|AAP83314.1| 976|Homo sapiens poly(ADP-ribose)
glycohydrolase protein.
Length = 976
Score = 130 bits (315), Expect = 5e-30
Identities = 74/210 (35%), Positives = 102/210 (48%), Gaps = 1/210 (0%)
Frame = +1
Query: 193 KKVIKLCTTMSTVTKNWLGVPISEIRGSQSPWGAPEFPLVVPAYNHSVLYHVQNGRPIDG 372
+K+ K + K WLG PI E+R + P PL+ P+ NH+V V R G
Sbjct: 437 RKIPKYVPPHLSPDKKWLGTPIEEMR--RMPRCGIRLPLLRPSANHTVTIRVDLLRA--G 492
Query: 373 DRP-PKPQIGRDKWDHEFVRMPCSNQSLYPFEDSNGDCHLKKRWEVIESSLWKPIRDSRE 549
+ P P P +D WD++ V+MPCS Q+LYP ED NG+ RWE+I+++L +
Sbjct: 493 EVPKPFPTHYKDLWDNKHVKMPCSEQNLYPVEDENGERTAGSRWELIQTALLNKFTRPQN 552
Query: 550 LANTILSYNTKFKKIWKFKALHKLFSEYLDEEETQYFFDVTXXXXXXXXXXXXXXXQSPI 729
L + IL YN + K W F AL + + L+E E Q+ + PI
Sbjct: 553 LKDAILKYNVAYSKKWDFTALIDFWDKVLEEAEAQHLYQSILPDMVKIALCLPNICTQPI 612
Query: 730 PLLKQHKNYXXXXXXXXXXXXXANAFFCTF 819
PLLKQ N+ ANAFFCTF
Sbjct: 613 PLLKQKMNHSITMSQEQIASLLANAFFCTF 642
>AF005043-1|AAB61614.1| 976|Homo sapiens poly(ADP-ribose)
glycohydrolase protein.
Length = 976
Score = 130 bits (315), Expect = 5e-30
Identities = 74/210 (35%), Positives = 102/210 (48%), Gaps = 1/210 (0%)
Frame = +1
Query: 193 KKVIKLCTTMSTVTKNWLGVPISEIRGSQSPWGAPEFPLVVPAYNHSVLYHVQNGRPIDG 372
+K+ K + K WLG PI E+R + P PL+ P+ NH+V V R G
Sbjct: 437 RKIPKYVPPHLSPDKKWLGTPIEEMR--RMPRCGIRLPLLRPSANHTVTIRVDLLRA--G 492
Query: 373 DRP-PKPQIGRDKWDHEFVRMPCSNQSLYPFEDSNGDCHLKKRWEVIESSLWKPIRDSRE 549
+ P P P +D WD++ V+MPCS Q+LYP ED NG+ RWE+I+++L +
Sbjct: 493 EVPKPFPTHYKDLWDNKHVKMPCSEQNLYPVEDENGERTAGSRWELIQTALLNKFTRPQN 552
Query: 550 LANTILSYNTKFKKIWKFKALHKLFSEYLDEEETQYFFDVTXXXXXXXXXXXXXXXQSPI 729
L + IL YN + K W F AL + + L+E E Q+ + PI
Sbjct: 553 LKDAILKYNVAYSKKWDFTALIDFWDKVLEEAEAQHLYQSILPDMVKIALCLPNICTQPI 612
Query: 730 PLLKQHKNYXXXXXXXXXXXXXANAFFCTF 819
PLLKQ N+ ANAFFCTF
Sbjct: 613 PLLKQKMNHSITMSQEQIASLLANAFFCTF 642
>DQ867088-1|ABH85399.1| 976|Homo sapiens poly (ADP-ribose)
glycohydrolase protein.
Length = 976
Score = 128 bits (308), Expect = 3e-29
Identities = 73/210 (34%), Positives = 101/210 (48%), Gaps = 1/210 (0%)
Frame = +1
Query: 193 KKVIKLCTTMSTVTKNWLGVPISEIRGSQSPWGAPEFPLVVPAYNHSVLYHVQNGRPIDG 372
+K+ K + K WLG PI E+R + P PL+ P+ NH+V V R G
Sbjct: 437 RKIPKYVPPHLSPDKKWLGTPIEEMR--RMPRCGIRLPLLRPSANHTVTIRVDLLRA--G 492
Query: 373 DRP-PKPQIGRDKWDHEFVRMPCSNQSLYPFEDSNGDCHLKKRWEVIESSLWKPIRDSRE 549
+ P P P + WD++ V+MPCS Q+LYP ED NG+ RWE+I+++L +
Sbjct: 493 EVPKPFPTHYKGLWDNKHVKMPCSEQNLYPVEDENGERTAGSRWELIQTALLNKFTRPQN 552
Query: 550 LANTILSYNTKFKKIWKFKALHKLFSEYLDEEETQYFFDVTXXXXXXXXXXXXXXXQSPI 729
L + IL YN + K W F AL + + L+E E Q+ + PI
Sbjct: 553 LKDAILKYNVAYSKKWDFTALIDFWDKVLEEAEAQHLYQSILPDMVKIALCLPNICTQPI 612
Query: 730 PLLKQHKNYXXXXXXXXXXXXXANAFFCTF 819
PLLKQ N+ ANAFFCTF
Sbjct: 613 PLLKQKMNHSITMSQEQIASLLANAFFCTF 642
>AL731572-3|CAI15135.1| 491|Homo sapiens poly (ADP-ribose)
glycohydrolase protein.
Length = 491
Score = 108 bits (260), Expect = 2e-23
Identities = 55/151 (36%), Positives = 75/151 (49%), Gaps = 1/151 (0%)
Frame = +1
Query: 370 GDRP-PKPQIGRDKWDHEFVRMPCSNQSLYPFEDSNGDCHLKKRWEVIESSLWKPIRDSR 546
G+ P P P +D WD++ V+MPCS Q+LYP ED NG+ RWE+I+++L +
Sbjct: 7 GEVPKPFPTHYKDLWDNKHVKMPCSEQNLYPVEDENGERTAGSRWELIQTALLNKFTRPQ 66
Query: 547 ELANTILSYNTKFKKIWKFKALHKLFSEYLDEEETQYFFDVTXXXXXXXXXXXXXXXQSP 726
L + IL YN + K W F AL + + L+E E Q+ + P
Sbjct: 67 NLKDAILKYNVAYSKKWDFTALIDFWDKVLEEAEAQHLYQSILPDMVKIALCLPNICTQP 126
Query: 727 IPLLKQHKNYXXXXXXXXXXXXXANAFFCTF 819
IPLLKQ N+ ANAFFCTF
Sbjct: 127 IPLLKQKMNHSITMSQEQIASLLANAFFCTF 157
>EF382674-1|ABR10027.1| 527|Homo sapiens poly(ADP-ribose)
glycohydrolase 60 kDa isoform precursor protein.
Length = 527
Score = 70.9 bits (166), Expect(2) = 4e-16
Identities = 37/116 (31%), Positives = 51/116 (43%)
Frame = +1
Query: 472 NGDCHLKKRWEVIESSLWKPIRDSRELANTILSYNTKFKKIWKFKALHKLFSEYLDEEET 651
NG+ RWE+I+++L + L + IL YN + K W F AL + + L+E E
Sbjct: 78 NGERTAGSRWELIQTALLNKFTRPQNLKDAILKYNVAYSKKWDFTALIDFWDKVLEEAEA 137
Query: 652 QYFFDVTXXXXXXXXXXXXXXXQSPIPLLKQHKNYXXXXXXXXXXXXXANAFFCTF 819
Q+ + PIPLLKQ N+ ANAFFCTF
Sbjct: 138 QHLYQSILPDMVKIALCLPNICTQPIPLLKQKMNHSITMSQEQIASLLANAFFCTF 193
Score = 33.9 bits (74), Expect(2) = 4e-16
Identities = 21/62 (33%), Positives = 30/62 (48%)
Frame = +1
Query: 193 KKVIKLCTTMSTVTKNWLGVPISEIRGSQSPWGAPEFPLVVPAYNHSVLYHVQNGRPIDG 372
+K+ K + K WLG PI E+R + P PL+ P+ NH+V + NG G
Sbjct: 29 RKIPKYVPPHLSPDKKWLGTPIEEMR--RMPRCGIRLPLLRPSANHTVT--IWNGERTAG 84
Query: 373 DR 378
R
Sbjct: 85 SR 86
>EF107108-1|ABK81123.1| 761|Homo sapiens sphingosine kinase-2
variant protein.
Length = 761
Score = 31.1 bits (67), Expect = 5.2
Identities = 10/35 (28%), Positives = 21/35 (60%)
Frame = +2
Query: 311 WCQHTIIPFCITCRTVDRLMETDRQNHR*DVISGI 415
WC++ ++P L++T+RQNH +++ G+
Sbjct: 261 WCKNHVLPMISEAGLSFNLIQTERQNHARELVQGL 295
>BC010671-1|AAH10671.1| 618|Homo sapiens SPHK2 protein protein.
Length = 618
Score = 31.1 bits (67), Expect = 5.2
Identities = 10/35 (28%), Positives = 21/35 (60%)
Frame = +2
Query: 311 WCQHTIIPFCITCRTVDRLMETDRQNHR*DVISGI 415
WC++ ++P L++T+RQNH +++ G+
Sbjct: 163 WCKNHVLPMISEAGLSFNLIQTERQNHARELVQGL 197
>BC006161-1|AAH06161.1| 654|Homo sapiens sphingosine kinase 2
protein.
Length = 654
Score = 31.1 bits (67), Expect = 5.2
Identities = 10/35 (28%), Positives = 21/35 (60%)
Frame = +2
Query: 311 WCQHTIIPFCITCRTVDRLMETDRQNHR*DVISGI 415
WC++ ++P L++T+RQNH +++ G+
Sbjct: 199 WCKNHVLPMISEAGLSFNLIQTERQNHARELVQGL 233
>AK000599-1|BAA91280.1| 354|Homo sapiens protein ( Homo sapiens
cDNA FLJ20592 fis, clone KAT08989. ).
Length = 354
Score = 31.1 bits (67), Expect = 5.2
Identities = 10/35 (28%), Positives = 21/35 (60%)
Frame = +2
Query: 311 WCQHTIIPFCITCRTVDRLMETDRQNHR*DVISGI 415
WC++ ++P L++T+RQNH +++ G+
Sbjct: 163 WCKNHVLPMISEAGLSFNLIQTERQNHARELVQGL 197
>AF245447-1|AAF74124.1| 618|Homo sapiens sphingosine kinase type 2
isoform protein.
Length = 618
Score = 31.1 bits (67), Expect = 5.2
Identities = 10/35 (28%), Positives = 21/35 (60%)
Frame = +2
Query: 311 WCQHTIIPFCITCRTVDRLMETDRQNHR*DVISGI 415
WC++ ++P L++T+RQNH +++ G+
Sbjct: 163 WCKNHVLPMISEAGLSFNLIQTERQNHARELVQGL 197
>CR457001-1|CAG33282.1| 273|Homo sapiens HSU79274 protein.
Length = 273
Score = 30.3 bits (65), Expect = 9.1
Identities = 14/50 (28%), Positives = 30/50 (60%)
Frame = +1
Query: 505 VIESSLWKPIRDSRELANTILSYNTKFKKIWKFKALHKLFSEYLDEEETQ 654
+I+ SLW+P+R ++E T + T+ K + F+ KLF + + ++++
Sbjct: 193 LIQHSLWRPVR-NKEGIKTGYASKTRCKSLKIFRRPRKLFMQTVSSDDSE 241
>BC020967-1|AAH20967.1| 273|Homo sapiens chromosome 12 open reading
frame 24 protein.
Length = 273
Score = 30.3 bits (65), Expect = 9.1
Identities = 14/50 (28%), Positives = 30/50 (60%)
Frame = +1
Query: 505 VIESSLWKPIRDSRELANTILSYNTKFKKIWKFKALHKLFSEYLDEEETQ 654
+I+ SLW+P+R ++E T + T+ K + F+ KLF + + ++++
Sbjct: 193 LIQHSLWRPVR-NKEGIKTGYASKTRCKSLKIFRRPRKLFMQTVSSDDSE 241
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 112,886,638
Number of Sequences: 237096
Number of extensions: 2307828
Number of successful extensions: 12398
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 12220
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 12382
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 10649685938
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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