Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P11_F_D10
(816 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
CR541695-1|CAG46496.1| 414|Homo sapiens IDH1 protein. 361 1e-99
CR533522-1|CAG38553.1| 414|Homo sapiens IDH1 protein. 361 1e-99
BC093020-1|AAH93020.1| 414|Homo sapiens isocitrate dehydrogenas... 361 1e-99
BC012846-1|AAH12846.1| 414|Homo sapiens IDH1 protein protein. 361 1e-99
AF113917-1|AAD29284.1| 414|Homo sapiens NADP+-dependent isocitr... 361 1e-99
AC016697-3|AAX93221.1| 414|Homo sapiens unknown protein. 361 1e-99
CR536499-1|CAG38738.1| 414|Homo sapiens IDH1 protein. 360 3e-99
BX537411-1|CAD97653.1| 414|Homo sapiens hypothetical protein pr... 359 5e-99
AF020038-1|AAD02918.1| 414|Homo sapiens NADP-dependent isocitra... 358 1e-98
X69433-1|CAA49208.1| 452|Homo sapiens isocitrate dehydrogenase... 338 2e-92
BC071828-1|AAH71828.1| 452|Homo sapiens isocitrate dehydrogenas... 338 2e-92
BC009244-1|AAH09244.1| 452|Homo sapiens isocitrate dehydrogenas... 338 2e-92
AK222916-1|BAD96636.1| 452|Homo sapiens isocitrate dehydrogenas... 338 2e-92
DQ403082-1|ABD77215.1| 371|Homo sapiens isocitrate dehydrogenas... 333 4e-91
U52144-1|AAC50455.1| 419|Homo sapiens isocitrate dehydrogenase ... 303 4e-82
U62389-1|AAB17375.1| 154|Homo sapiens putative cytosolic NADP-d... 208 2e-53
AL590225-2|CAI13628.2| 817|Homo sapiens chromosome 6 open readi... 31 6.6
AL589910-3|CAM22453.1| 817|Homo sapiens chromosome 6 open readi... 31 6.6
AL365508-2|CAI13226.2| 817|Homo sapiens chromosome 6 open readi... 31 6.6
AL035593-2|CAI20139.2| 817|Homo sapiens chromosome 6 open readi... 31 6.6
AK125385-1|BAC86152.1| 817|Homo sapiens protein ( Homo sapiens ... 31 6.6
AK055461-1|BAB70925.1| 593|Homo sapiens protein ( Homo sapiens ... 31 6.6
BC020198-1|AAH20198.1| 567|Homo sapiens MEGF10 protein protein. 30 8.7
AB058676-1|BAB47409.1| 1140|Homo sapiens MEGF10 protein (KIAA178... 30 8.7
>CR541695-1|CAG46496.1| 414|Homo sapiens IDH1 protein.
Length = 414
Score = 361 bits (889), Expect = 1e-99
Identities = 165/220 (75%), Positives = 194/220 (88%), Gaps = 2/220 (0%)
Frame = +2
Query: 161 DEMTRIIWDLIKEKLIIPFLDIELHVYDLGMENRDKTDDQVTIDCAEAIKKYNVGIKCAT 340
DEMTRIIW+LIKEKLI P+++++LH YDLG+ENRD T+DQVT D AEAIKK+NVG+KCAT
Sbjct: 16 DEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCAT 75
Query: 341 ITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTGWDKPIIIGRHAH 520
ITPDEKRVEEFKLK+MWKSPNGTIRNILGGTVFREAIICKNIPRLV+GW KPIIIGRHA+
Sbjct: 76 ITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGRHAY 135
Query: 521 ADQYKATDFVVPGAGTLEIIFKPESG-EAIKHVVHEY-KGAGVALAMFNTDASIIDFAHS 694
DQY+ATDFVVPG G +EI + P G + + ++VH + +G GVA+ M+N D SI DFAHS
Sbjct: 136 GDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHS 195
Query: 695 SFKFALDRKYPLYLSTKNTILKKYDGRFKDIFQDIYDKEY 814
SF+ AL + +PLYLSTKNTILKKYDGRFKDIFQ+IYDK+Y
Sbjct: 196 SFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQY 235
>CR533522-1|CAG38553.1| 414|Homo sapiens IDH1 protein.
Length = 414
Score = 361 bits (889), Expect = 1e-99
Identities = 165/220 (75%), Positives = 195/220 (88%), Gaps = 2/220 (0%)
Frame = +2
Query: 161 DEMTRIIWDLIKEKLIIPFLDIELHVYDLGMENRDKTDDQVTIDCAEAIKKYNVGIKCAT 340
DEMTRIIW+LIKEKLIIP+++++LH YDLG+ENRD T+DQVT D AEAIKK+NVG+KCAT
Sbjct: 16 DEMTRIIWELIKEKLIIPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCAT 75
Query: 341 ITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTGWDKPIIIGRHAH 520
ITPDEKRVEEFKLK+MWKSPNGTIRNILGGTVFREAIICKNIPRLV+GW +PIIIGRHA+
Sbjct: 76 ITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVEPIIIGRHAY 135
Query: 521 ADQYKATDFVVPGAGTLEIIFKPESG-EAIKHVVHEY-KGAGVALAMFNTDASIIDFAHS 694
DQY+ATDFVVPG G +EI + P G + + ++VH + +G GVA+ M+N D SI DFAHS
Sbjct: 136 GDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHS 195
Query: 695 SFKFALDRKYPLYLSTKNTILKKYDGRFKDIFQDIYDKEY 814
SF+ AL + +PLYLSTKNTILKKYDGRFKDIFQ+IYDK+Y
Sbjct: 196 SFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQY 235
>BC093020-1|AAH93020.1| 414|Homo sapiens isocitrate dehydrogenase 1
(NADP+), soluble protein.
Length = 414
Score = 361 bits (889), Expect = 1e-99
Identities = 165/220 (75%), Positives = 194/220 (88%), Gaps = 2/220 (0%)
Frame = +2
Query: 161 DEMTRIIWDLIKEKLIIPFLDIELHVYDLGMENRDKTDDQVTIDCAEAIKKYNVGIKCAT 340
DEMTRIIW+LIKEKLI P+++++LH YDLG+ENRD T+DQVT D AEAIKK+NVG+KCAT
Sbjct: 16 DEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCAT 75
Query: 341 ITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTGWDKPIIIGRHAH 520
ITPDEKRVEEFKLK+MWKSPNGTIRNILGGTVFREAIICKNIPRLV+GW KPIIIGRHA+
Sbjct: 76 ITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGRHAY 135
Query: 521 ADQYKATDFVVPGAGTLEIIFKPESG-EAIKHVVHEY-KGAGVALAMFNTDASIIDFAHS 694
DQY+ATDFVVPG G +EI + P G + + ++VH + +G GVA+ M+N D SI DFAHS
Sbjct: 136 GDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHS 195
Query: 695 SFKFALDRKYPLYLSTKNTILKKYDGRFKDIFQDIYDKEY 814
SF+ AL + +PLYLSTKNTILKKYDGRFKDIFQ+IYDK+Y
Sbjct: 196 SFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQY 235
>BC012846-1|AAH12846.1| 414|Homo sapiens IDH1 protein protein.
Length = 414
Score = 361 bits (889), Expect = 1e-99
Identities = 165/220 (75%), Positives = 194/220 (88%), Gaps = 2/220 (0%)
Frame = +2
Query: 161 DEMTRIIWDLIKEKLIIPFLDIELHVYDLGMENRDKTDDQVTIDCAEAIKKYNVGIKCAT 340
DEMTRIIW+LIKEKLI P+++++LH YDLG+ENRD T+DQVT D AEAIKK+NVG+KCAT
Sbjct: 16 DEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCAT 75
Query: 341 ITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTGWDKPIIIGRHAH 520
ITPDEKRVEEFKLK+MWKSPNGTIRNILGGTVFREAIICKNIPRLV+GW KPIIIGRHA+
Sbjct: 76 ITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGRHAY 135
Query: 521 ADQYKATDFVVPGAGTLEIIFKPESG-EAIKHVVHEY-KGAGVALAMFNTDASIIDFAHS 694
DQY+ATDFVVPG G +EI + P G + + ++VH + +G GVA+ M+N D SI DFAHS
Sbjct: 136 GDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHS 195
Query: 695 SFKFALDRKYPLYLSTKNTILKKYDGRFKDIFQDIYDKEY 814
SF+ AL + +PLYLSTKNTILKKYDGRFKDIFQ+IYDK+Y
Sbjct: 196 SFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQY 235
>AF113917-1|AAD29284.1| 414|Homo sapiens NADP+-dependent isocitrate
dehydrogenase protein.
Length = 414
Score = 361 bits (889), Expect = 1e-99
Identities = 165/220 (75%), Positives = 194/220 (88%), Gaps = 2/220 (0%)
Frame = +2
Query: 161 DEMTRIIWDLIKEKLIIPFLDIELHVYDLGMENRDKTDDQVTIDCAEAIKKYNVGIKCAT 340
DEMTRIIW+LIKEKLI P+++++LH YDLG+ENRD T+DQVT D AEAIKK+NVG+KCAT
Sbjct: 16 DEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCAT 75
Query: 341 ITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTGWDKPIIIGRHAH 520
ITPDEKRVEEFKLK+MWKSPNGTIRNILGGTVFREAIICKNIPRLV+GW KPIIIGRHA+
Sbjct: 76 ITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGRHAY 135
Query: 521 ADQYKATDFVVPGAGTLEIIFKPESG-EAIKHVVHEY-KGAGVALAMFNTDASIIDFAHS 694
DQY+ATDFVVPG G +EI + P G + + ++VH + +G GVA+ M+N D SI DFAHS
Sbjct: 136 GDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHS 195
Query: 695 SFKFALDRKYPLYLSTKNTILKKYDGRFKDIFQDIYDKEY 814
SF+ AL + +PLYLSTKNTILKKYDGRFKDIFQ+IYDK+Y
Sbjct: 196 SFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQY 235
>AC016697-3|AAX93221.1| 414|Homo sapiens unknown protein.
Length = 414
Score = 361 bits (889), Expect = 1e-99
Identities = 165/220 (75%), Positives = 194/220 (88%), Gaps = 2/220 (0%)
Frame = +2
Query: 161 DEMTRIIWDLIKEKLIIPFLDIELHVYDLGMENRDKTDDQVTIDCAEAIKKYNVGIKCAT 340
DEMTRIIW+LIKEKLI P+++++LH YDLG+ENRD T+DQVT D AEAIKK+NVG+KCAT
Sbjct: 16 DEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCAT 75
Query: 341 ITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTGWDKPIIIGRHAH 520
ITPDEKRVEEFKLK+MWKSPNGTIRNILGGTVFREAIICKNIPRLV+GW KPIIIGRHA+
Sbjct: 76 ITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGRHAY 135
Query: 521 ADQYKATDFVVPGAGTLEIIFKPESG-EAIKHVVHEY-KGAGVALAMFNTDASIIDFAHS 694
DQY+ATDFVVPG G +EI + P G + + ++VH + +G GVA+ M+N D SI DFAHS
Sbjct: 136 GDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHS 195
Query: 695 SFKFALDRKYPLYLSTKNTILKKYDGRFKDIFQDIYDKEY 814
SF+ AL + +PLYLSTKNTILKKYDGRFKDIFQ+IYDK+Y
Sbjct: 196 SFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQY 235
>CR536499-1|CAG38738.1| 414|Homo sapiens IDH1 protein.
Length = 414
Score = 360 bits (886), Expect = 3e-99
Identities = 164/220 (74%), Positives = 194/220 (88%), Gaps = 2/220 (0%)
Frame = +2
Query: 161 DEMTRIIWDLIKEKLIIPFLDIELHVYDLGMENRDKTDDQVTIDCAEAIKKYNVGIKCAT 340
DEMTRIIW+LIKEKLI P+++++LH YDLG+ENRD T+DQVT D AEAIKK+NVG+KCAT
Sbjct: 16 DEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCAT 75
Query: 341 ITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTGWDKPIIIGRHAH 520
ITPDEKRVEEFKLK+MWKSPNGTIRNILGGTVFREAIICKNIPRLV+GW KPIIIGRHA+
Sbjct: 76 ITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGRHAY 135
Query: 521 ADQYKATDFVVPGAGTLEIIFKPESG-EAIKHVVHEY-KGAGVALAMFNTDASIIDFAHS 694
DQY+ATDFVVPG G +E+ + P G + + ++VH + +G GVA+ M+N D SI DFAHS
Sbjct: 136 GDQYRATDFVVPGPGKVEMTYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHS 195
Query: 695 SFKFALDRKYPLYLSTKNTILKKYDGRFKDIFQDIYDKEY 814
SF+ AL + +PLYLSTKNTILKKYDGRFKDIFQ+IYDK+Y
Sbjct: 196 SFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQY 235
>BX537411-1|CAD97653.1| 414|Homo sapiens hypothetical protein
protein.
Length = 414
Score = 359 bits (884), Expect = 5e-99
Identities = 165/220 (75%), Positives = 193/220 (87%), Gaps = 2/220 (0%)
Frame = +2
Query: 161 DEMTRIIWDLIKEKLIIPFLDIELHVYDLGMENRDKTDDQVTIDCAEAIKKYNVGIKCAT 340
DEMTRIIW+LIKEKLI P+++++LH YDLG+ENRD T+DQVT D AEAIKK+NVG+KCAT
Sbjct: 16 DEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCAT 75
Query: 341 ITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTGWDKPIIIGRHAH 520
ITPDEKRVEEFKLK+MWKSPNGTIRNILGGTVFREAIICKNIPRLV+GW KPIIIGRHA+
Sbjct: 76 ITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGRHAY 135
Query: 521 ADQYKATDFVVPGAGTLEIIFKPESG-EAIKHVVHEYK-GAGVALAMFNTDASIIDFAHS 694
DQY+ATDFVVPG G +EI + P G + + ++VH + G GVA+ M+N D SI DFAHS
Sbjct: 136 GDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNSEGGGGVAMGMYNQDKSIEDFAHS 195
Query: 695 SFKFALDRKYPLYLSTKNTILKKYDGRFKDIFQDIYDKEY 814
SF+ AL + +PLYLSTKNTILKKYDGRFKDIFQ+IYDK+Y
Sbjct: 196 SFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQY 235
>AF020038-1|AAD02918.1| 414|Homo sapiens NADP-dependent isocitrate
dehydrogenase protein.
Length = 414
Score = 358 bits (881), Expect = 1e-98
Identities = 164/220 (74%), Positives = 193/220 (87%), Gaps = 2/220 (0%)
Frame = +2
Query: 161 DEMTRIIWDLIKEKLIIPFLDIELHVYDLGMENRDKTDDQVTIDCAEAIKKYNVGIKCAT 340
DEMTRIIW+LIKEKLI P+++++LH YDLG+ENRD T+DQVT D AEAIKK+NVG+KCAT
Sbjct: 16 DEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCAT 75
Query: 341 ITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTGWDKPIIIGRHAH 520
ITPDEKRVEEFKLK+MWKSPNGTIRNILGGTVFREAIICKNIPRLV+GW KPIIIGRHA+
Sbjct: 76 ITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGRHAY 135
Query: 521 ADQYKATDFVVPGAGTLEIIFKPESG-EAIKHVVHEY-KGAGVALAMFNTDASIIDFAHS 694
DQY+ATDFVVPG G +EI + P G + + ++VH + +G GVA+ M+N D SI DFAHS
Sbjct: 136 GDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHS 195
Query: 695 SFKFALDRKYPLYLSTKNTILKKYDGRFKDIFQDIYDKEY 814
SF+ AL + +PLYLSTKNTILK YDGRFKDIFQ+IYDK+Y
Sbjct: 196 SFQMALSKGWPLYLSTKNTILKIYDGRFKDIFQEIYDKQY 235
>X69433-1|CAA49208.1| 452|Homo sapiens isocitrate dehydrogenase
(NADP+) protein.
Length = 452
Score = 338 bits (830), Expect = 2e-92
Identities = 153/219 (69%), Positives = 179/219 (81%), Gaps = 1/219 (0%)
Frame = +2
Query: 161 DEMTRIIWDLIKEKLIIPFLDIELHVYDLGMENRDKTDDQVTIDCAEAIKKYNVGIKCAT 340
DEMTRIIW IKEKLI+P +DI+L +DLG+ NRD+TDDQVTID A A +KY+V +KCAT
Sbjct: 56 DEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQVTIDSALATQKYSVAVKCAT 115
Query: 341 ITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTGWDKPIIIGRHAH 520
ITPDE RVEEFKLKKMWKSPNGTIRNILGGTVFRE IICKNIPRLV GW KPI IGRHAH
Sbjct: 116 ITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVPGWTKPITIGRHAH 175
Query: 521 ADQYKATDFVVPGAGTLEIIFKPESGEAIKH-VVHEYKGAGVALAMFNTDASIIDFAHSS 697
DQYKATDFV AGT +++F P+ G +K V+ + GV + M+NTD SI FAHS
Sbjct: 176 GDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAGGVGMGMYNTDESISGFAHSC 235
Query: 698 FKFALDRKYPLYLSTKNTILKKYDGRFKDIFQDIYDKEY 814
F++A+ +K+PLY+STKNTILK YDGRFKDIFQ+I+DK Y
Sbjct: 236 FQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHY 274
>BC071828-1|AAH71828.1| 452|Homo sapiens isocitrate dehydrogenase 2
(NADP+), mitochondrial protein.
Length = 452
Score = 338 bits (830), Expect = 2e-92
Identities = 153/219 (69%), Positives = 179/219 (81%), Gaps = 1/219 (0%)
Frame = +2
Query: 161 DEMTRIIWDLIKEKLIIPFLDIELHVYDLGMENRDKTDDQVTIDCAEAIKKYNVGIKCAT 340
DEMTRIIW IKEKLI+P +DI+L +DLG+ NRD+TDDQVTID A A +KY+V +KCAT
Sbjct: 56 DEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQVTIDSALATQKYSVAVKCAT 115
Query: 341 ITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTGWDKPIIIGRHAH 520
ITPDE RVEEFKLKKMWKSPNGTIRNILGGTVFRE IICKNIPRLV GW KPI IGRHAH
Sbjct: 116 ITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVPGWTKPITIGRHAH 175
Query: 521 ADQYKATDFVVPGAGTLEIIFKPESGEAIKH-VVHEYKGAGVALAMFNTDASIIDFAHSS 697
DQYKATDFV AGT +++F P+ G +K V+ + GV + M+NTD SI FAHS
Sbjct: 176 GDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAGGVGMGMYNTDESISGFAHSC 235
Query: 698 FKFALDRKYPLYLSTKNTILKKYDGRFKDIFQDIYDKEY 814
F++A+ +K+PLY+STKNTILK YDGRFKDIFQ+I+DK Y
Sbjct: 236 FQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHY 274
>BC009244-1|AAH09244.1| 452|Homo sapiens isocitrate dehydrogenase 2
(NADP+), mitochondrial protein.
Length = 452
Score = 338 bits (830), Expect = 2e-92
Identities = 153/219 (69%), Positives = 179/219 (81%), Gaps = 1/219 (0%)
Frame = +2
Query: 161 DEMTRIIWDLIKEKLIIPFLDIELHVYDLGMENRDKTDDQVTIDCAEAIKKYNVGIKCAT 340
DEMTRIIW IKEKLI+P +DI+L +DLG+ NRD+TDDQVTID A A +KY+V +KCAT
Sbjct: 56 DEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQVTIDSALATQKYSVAVKCAT 115
Query: 341 ITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTGWDKPIIIGRHAH 520
ITPDE RVEEFKLKKMWKSPNGTIRNILGGTVFRE IICKNIPRLV GW KPI IGRHAH
Sbjct: 116 ITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVPGWTKPITIGRHAH 175
Query: 521 ADQYKATDFVVPGAGTLEIIFKPESGEAIKH-VVHEYKGAGVALAMFNTDASIIDFAHSS 697
DQYKATDFV AGT +++F P+ G +K V+ + GV + M+NTD SI FAHS
Sbjct: 176 GDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAGGVGMGMYNTDESISGFAHSC 235
Query: 698 FKFALDRKYPLYLSTKNTILKKYDGRFKDIFQDIYDKEY 814
F++A+ +K+PLY+STKNTILK YDGRFKDIFQ+I+DK Y
Sbjct: 236 FQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHY 274
>AK222916-1|BAD96636.1| 452|Homo sapiens isocitrate dehydrogenase 2
(NADP+), mitochondrial precursor variant protein.
Length = 452
Score = 338 bits (830), Expect = 2e-92
Identities = 153/219 (69%), Positives = 179/219 (81%), Gaps = 1/219 (0%)
Frame = +2
Query: 161 DEMTRIIWDLIKEKLIIPFLDIELHVYDLGMENRDKTDDQVTIDCAEAIKKYNVGIKCAT 340
DEMTRIIW IKEKLI+P +DI+L +DLG+ NRD+TDDQVTID A A +KY+V +KCAT
Sbjct: 56 DEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQVTIDSALATQKYSVAVKCAT 115
Query: 341 ITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTGWDKPIIIGRHAH 520
ITPDE RVEEFKLKKMWKSPNGTIRNILGGTVFRE IICKNIPRLV GW KPI IGRHAH
Sbjct: 116 ITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVPGWTKPITIGRHAH 175
Query: 521 ADQYKATDFVVPGAGTLEIIFKPESGEAIKH-VVHEYKGAGVALAMFNTDASIIDFAHSS 697
DQYKATDFV AGT +++F P+ G +K V+ + GV + M+NTD SI FAHS
Sbjct: 176 GDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAGGVGMGMYNTDESISGFAHSC 235
Query: 698 FKFALDRKYPLYLSTKNTILKKYDGRFKDIFQDIYDKEY 814
F++A+ +K+PLY+STKNTILK YDGRFKDIFQ+I+DK Y
Sbjct: 236 FQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHY 274
>DQ403082-1|ABD77215.1| 371|Homo sapiens isocitrate dehydrogenase 1
protein.
Length = 371
Score = 333 bits (819), Expect = 4e-91
Identities = 152/206 (73%), Positives = 180/206 (87%), Gaps = 2/206 (0%)
Frame = +2
Query: 203 LIIPFLDIELHVYDLGMENRDKTDDQVTIDCAEAIKKYNVGIKCATITPDEKRVEEFKLK 382
LI P+++++LH YDLG+ENRD T+DQVT D AEAIKK+NVG+KCATITPDEKRVEEFKLK
Sbjct: 1 LIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDEKRVEEFKLK 60
Query: 383 KMWKSPNGTIRNILGGTVFREAIICKNIPRLVTGWDKPIIIGRHAHADQYKATDFVVPGA 562
+MWKSPNGTIRNILGGTVFREAIICKNIPRLV+GW KPIIIGRHA+ DQY+ATDFVVPG
Sbjct: 61 QMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVPGP 120
Query: 563 GTLEIIFKPESG-EAIKHVVHEY-KGAGVALAMFNTDASIIDFAHSSFKFALDRKYPLYL 736
G +EI + P G + + ++VH + +G GVA+ M+N D SI DFAHSSF+ AL + +PLYL
Sbjct: 121 GKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYL 180
Query: 737 STKNTILKKYDGRFKDIFQDIYDKEY 814
STKNTILKKYDGRFKDIFQ+IYDK+Y
Sbjct: 181 STKNTILKKYDGRFKDIFQEIYDKQY 206
>U52144-1|AAC50455.1| 419|Homo sapiens isocitrate dehydrogenase
protein.
Length = 419
Score = 303 bits (745), Expect = 4e-82
Identities = 137/200 (68%), Positives = 162/200 (81%), Gaps = 1/200 (0%)
Frame = +2
Query: 218 LDIELHVYDLGMENRDKTDDQVTIDCAEAIKKYNVGIKCATITPDEKRVEEFKLKKMWKS 397
LD++L +DLG+ NRD+TDDQVTID A A +KY+V +KCATITPDE RVEEFKLKKMWKS
Sbjct: 42 LDVQLKYFDLGLPNRDQTDDQVTIDSALATQKYSVAVKCATITPDEARVEEFKLKKMWKS 101
Query: 398 PNGTIRNILGGTVFREAIICKNIPRLVTGWDKPIIIGRHAHADQYKATDFVVPGAGTLEI 577
PNGTIRNI GGTVFRE IICKNIPRLV GW KPI IGRHAH DQYKATDFV AGT ++
Sbjct: 102 PNGTIRNIHGGTVFREPIICKNIPRLVPGWTKPITIGRHAHGDQYKATDFVADRAGTFKM 161
Query: 578 IFKPESGEAIKH-VVHEYKGAGVALAMFNTDASIIDFAHSSFKFALDRKYPLYLSTKNTI 754
+F P+ G +K V+ + GV + M+NTD SI FAHS F++A+ +K+PLY+STKNTI
Sbjct: 162 VFTPKDGSGVKEWEVYNFPAGGVGMGMYNTDESISGFAHSCFQYAIQKKWPLYMSTKNTI 221
Query: 755 LKKYDGRFKDIFQDIYDKEY 814
LK YDGRFKDIFQ+I+DK Y
Sbjct: 222 LKAYDGRFKDIFQEIFDKHY 241
>U62389-1|AAB17375.1| 154|Homo sapiens putative cytosolic
NADP-dependent isocitrate dehydrogenase protein.
Length = 154
Score = 208 bits (508), Expect = 2e-53
Identities = 96/136 (70%), Positives = 114/136 (83%), Gaps = 2/136 (1%)
Frame = +2
Query: 413 RNILGGTVFREAIICKNIPRLVTGWDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPE 592
RNILGGTVF EAIICKNIPRLV+GW KPIIIGRHA+ DQY+ATDFVVPG G +EI + P
Sbjct: 1 RNILGGTVFXEAIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPS 60
Query: 593 SG-EAIKHVVHEY-KGAGVALAMFNTDASIIDFAHSSFKFALDRKYPLYLSTKNTILKKY 766
G + + ++VH + +G GVA+ M+N D SI DFAHSSF+ AL + +PLYLSTKNTILKKY
Sbjct: 61 DGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKY 120
Query: 767 DGRFKDIFQDIYDKEY 814
DGRFKDIFQ+IYDK+Y
Sbjct: 121 DGRFKDIFQEIYDKQY 136
>AL590225-2|CAI13628.2| 817|Homo sapiens chromosome 6 open reading
frame 170 protein.
Length = 817
Score = 30.7 bits (66), Expect = 6.6
Identities = 28/91 (30%), Positives = 37/91 (40%), Gaps = 1/91 (1%)
Frame = -3
Query: 478 YKSRYILANNSLPENSTTKNITDGPIRAFPHFLQFKFFNS-LLIRSYGRTFDAHIVFLYG 302
Y + Y L N N T ++ + P + NS IRS +HI L
Sbjct: 318 YPAIYELVRNQDLPNKTEYSLREVPTCVIDIIDRLIILNSEAKIRSLFNYEQSHIFGLRL 377
Query: 301 LSTINCNLIISLITIFHTQVVDM*FNVQERN 209
LS I C+L L+ QV +M N QE N
Sbjct: 378 LSVICCDLDTLLLLEAQYQVSEMLLNAQEEN 408
>AL589910-3|CAM22453.1| 817|Homo sapiens chromosome 6 open reading
frame 170 protein.
Length = 817
Score = 30.7 bits (66), Expect = 6.6
Identities = 28/91 (30%), Positives = 37/91 (40%), Gaps = 1/91 (1%)
Frame = -3
Query: 478 YKSRYILANNSLPENSTTKNITDGPIRAFPHFLQFKFFNS-LLIRSYGRTFDAHIVFLYG 302
Y + Y L N N T ++ + P + NS IRS +HI L
Sbjct: 318 YPAIYELVRNQDLPNKTEYSLREVPTCVIDIIDRLIILNSEAKIRSLFNYEQSHIFGLRL 377
Query: 301 LSTINCNLIISLITIFHTQVVDM*FNVQERN 209
LS I C+L L+ QV +M N QE N
Sbjct: 378 LSVICCDLDTLLLLEAQYQVSEMLLNAQEEN 408
>AL365508-2|CAI13226.2| 817|Homo sapiens chromosome 6 open reading
frame 170 protein.
Length = 817
Score = 30.7 bits (66), Expect = 6.6
Identities = 28/91 (30%), Positives = 37/91 (40%), Gaps = 1/91 (1%)
Frame = -3
Query: 478 YKSRYILANNSLPENSTTKNITDGPIRAFPHFLQFKFFNS-LLIRSYGRTFDAHIVFLYG 302
Y + Y L N N T ++ + P + NS IRS +HI L
Sbjct: 318 YPAIYELVRNQDLPNKTEYSLREVPTCVIDIIDRLIILNSEAKIRSLFNYEQSHIFGLRL 377
Query: 301 LSTINCNLIISLITIFHTQVVDM*FNVQERN 209
LS I C+L L+ QV +M N QE N
Sbjct: 378 LSVICCDLDTLLLLEAQYQVSEMLLNAQEEN 408
>AL035593-2|CAI20139.2| 817|Homo sapiens chromosome 6 open reading
frame 170 protein.
Length = 817
Score = 30.7 bits (66), Expect = 6.6
Identities = 28/91 (30%), Positives = 37/91 (40%), Gaps = 1/91 (1%)
Frame = -3
Query: 478 YKSRYILANNSLPENSTTKNITDGPIRAFPHFLQFKFFNS-LLIRSYGRTFDAHIVFLYG 302
Y + Y L N N T ++ + P + NS IRS +HI L
Sbjct: 318 YPAIYELVRNQDLPNKTEYSLREVPTCVIDIIDRLIILNSEAKIRSLFNYEQSHIFGLRL 377
Query: 301 LSTINCNLIISLITIFHTQVVDM*FNVQERN 209
LS I C+L L+ QV +M N QE N
Sbjct: 378 LSVICCDLDTLLLLEAQYQVSEMLLNAQEEN 408
>AK125385-1|BAC86152.1| 817|Homo sapiens protein ( Homo sapiens
cDNA FLJ43395 fis, clone OCBBF2008770. ).
Length = 817
Score = 30.7 bits (66), Expect = 6.6
Identities = 28/91 (30%), Positives = 37/91 (40%), Gaps = 1/91 (1%)
Frame = -3
Query: 478 YKSRYILANNSLPENSTTKNITDGPIRAFPHFLQFKFFNS-LLIRSYGRTFDAHIVFLYG 302
Y + Y L N N T ++ + P + NS IRS +HI L
Sbjct: 318 YPAIYELVRNQDLPNKTEYSLREVPTCVIDIIDRLIILNSEAKIRSLFNYEQSHIFGLRL 377
Query: 301 LSTINCNLIISLITIFHTQVVDM*FNVQERN 209
LS I C+L L+ QV +M N QE N
Sbjct: 378 LSVICCDLDTLLLLEAQYQVSEMLLNAQEEN 408
>AK055461-1|BAB70925.1| 593|Homo sapiens protein ( Homo sapiens
cDNA FLJ30899 fis, clone FEBRA2005726. ).
Length = 593
Score = 30.7 bits (66), Expect = 6.6
Identities = 28/91 (30%), Positives = 37/91 (40%), Gaps = 1/91 (1%)
Frame = -3
Query: 478 YKSRYILANNSLPENSTTKNITDGPIRAFPHFLQFKFFNS-LLIRSYGRTFDAHIVFLYG 302
Y + Y L N N T ++ + P + NS IRS +HI L
Sbjct: 94 YPAIYELVRNQDLPNKTEYSLREVPTCVIDIIDRLIILNSEAKIRSLFNYEQSHIFGLRL 153
Query: 301 LSTINCNLIISLITIFHTQVVDM*FNVQERN 209
LS I C+L L+ QV +M N QE N
Sbjct: 154 LSVICCDLDTLLLLEAQYQVSEMLLNAQEEN 184
>BC020198-1|AAH20198.1| 567|Homo sapiens MEGF10 protein protein.
Length = 567
Score = 30.3 bits (65), Expect = 8.7
Identities = 21/68 (30%), Positives = 24/68 (35%), Gaps = 3/68 (4%)
Frame = +1
Query: 475 CNRVGQTHHHWTSCSC*SIQSN*LC---CPRCWYS*NNLQT*IW*GNKTCSS*VQGCRCS 645
C G HH CSC S +C CP + N Q TC + C CS
Sbjct: 240 CQNGGVCHHVTGECSCPSGWMGTVCGQPCPEGRFGKNCSQECQCHNGGTCDAATGQCHCS 299
Query: 646 TGYV*H*C 669
GY C
Sbjct: 300 PGYTGERC 307
>AB058676-1|BAB47409.1| 1140|Homo sapiens MEGF10 protein (KIAA1780)
protein.
Length = 1140
Score = 30.3 bits (65), Expect = 8.7
Identities = 21/68 (30%), Positives = 24/68 (35%), Gaps = 3/68 (4%)
Frame = +1
Query: 475 CNRVGQTHHHWTSCSC*SIQSN*LC---CPRCWYS*NNLQT*IW*GNKTCSS*VQGCRCS 645
C G HH CSC S +C CP + N Q TC + C CS
Sbjct: 240 CQNGGVCHHVTGECSCPSGWMGTVCGQPCPEGRFGKNCSQECQCHNGGTCDAATGQCHCS 299
Query: 646 TGYV*H*C 669
GY C
Sbjct: 300 PGYTGERC 307
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 114,772,801
Number of Sequences: 237096
Number of extensions: 2478773
Number of successful extensions: 8413
Number of sequences better than 10.0: 24
Number of HSP's better than 10.0 without gapping: 8226
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 8391
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 10147868276
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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