Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P10_pT_I06
(741 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC058935-1|AAH58935.1| 239|Homo sapiens LRRC57 protein protein. 201 2e-51
AK094131-1|BAC04294.1| 239|Homo sapiens (EC 2.4.1.101). protein. 201 2e-51
AK094891-1|BAC04451.1| 239|Homo sapiens protein ( Homo sapiens ... 199 7e-51
BC007504-1|AAH07504.1| 712|Homo sapiens leucine-rich repeats an... 104 3e-22
AB020669-1|BAA74885.2| 584|Homo sapiens KIAA0862 protein protein. 103 5e-22
BC050445-1|AAH50445.1| 582|Homo sapiens soc-2 suppressor of cle... 103 7e-22
AL158163-3|CAH72813.1| 372|Homo sapiens soc-2 suppressor of cle... 103 7e-22
AL158163-2|CAH72812.1| 582|Homo sapiens soc-2 suppressor of cle... 103 7e-22
AF068920-1|AAC39856.1| 582|Homo sapiens Ras-binding protein SUR... 103 7e-22
AF054828-1|AAC25698.1| 582|Homo sapiens leucine-rich repeat pro... 103 7e-22
BC125224-1|AAI25225.1| 748|Homo sapiens LRCH2 protein protein. 103 9e-22
BC008586-1|AAH08586.1| 602|Homo sapiens leucine rich repeat con... 101 3e-21
BC003407-1|AAH03407.2| 581|Homo sapiens LRRC40 protein protein. 101 3e-21
AL353771-3|CAI22332.1| 602|Homo sapiens leucine rich repeat con... 101 3e-21
AK022951-1|BAB14326.1| 602|Homo sapiens protein ( Homo sapiens ... 101 3e-21
BC117472-1|AAI17473.1| 763|Homo sapiens LRCH1 protein protein. 97 4e-20
BC112937-1|AAI12938.1| 696|Homo sapiens LRCH1 protein protein. 97 4e-20
AY050632-1|AAK95568.1| 728|Homo sapiens neuronal protein isofor... 97 4e-20
AY050631-1|AAK95567.1| 696|Homo sapiens neuronal protein isofor... 97 4e-20
AB023233-1|BAA76860.1| 793|Homo sapiens KIAA1016 protein protein. 97 4e-20
BC024159-1|AAH24159.2| 858|Homo sapiens leucine rich repeat con... 97 8e-20
AY358874-1|AAQ89233.1| 501|Homo sapiens LRRC5 protein. 97 8e-20
AL391497-3|CAH72226.1| 858|Homo sapiens leucine rich repeat con... 97 8e-20
AK001332-1|BAA91631.1| 682|Homo sapiens protein ( Homo sapiens ... 97 8e-20
AL359880-1|CAH70792.1| 734|Homo sapiens leucine-rich repeats an... 96 1e-19
AL138704-1|CAH73642.1| 734|Homo sapiens leucine-rich repeats an... 96 1e-19
AK222787-1|BAD96507.1| 671|Homo sapiens leucine rich repeat con... 96 1e-19
D63481-1|BAA09768.3| 1630|Homo sapiens KIAA0147 protein protein. 95 2e-19
AY062238-1|AAL38976.1| 1630|Homo sapiens scribble protein. 95 2e-19
AF271734-1|AAP88018.1| 1601|Homo sapiens SCRIB1 variant N1 protein. 95 2e-19
AF240677-1|AAP88017.1| 1630|Homo sapiens CRIB1 protein. 95 2e-19
BC003193-1|AAH03193.1| 524|Homo sapiens leucine rich repeat con... 94 4e-19
AL513211-1|CAI17358.1| 524|Homo sapiens leucine rich repeat con... 94 4e-19
AL033384-1|CAI21666.1| 524|Homo sapiens leucine rich repeat con... 94 4e-19
AF359380-1|AAK72246.1| 524|Homo sapiens LANO adaptor protein pr... 94 4e-19
AF332199-1|AAK69623.1| 524|Homo sapiens leucine-rich repeats pr... 94 4e-19
BC115015-1|AAI15016.1| 1367|Homo sapiens ERBB2IP protein protein. 91 3e-18
BC126464-1|AAI26465.1| 1371|Homo sapiens erbb2 interacting prote... 91 4e-18
BC115012-1|AAI15013.1| 1371|Homo sapiens erbb2 interacting prote... 91 4e-18
BC050692-1|AAH50692.1| 633|Homo sapiens ERBB2IP protein protein. 91 4e-18
AF276423-1|AAK69431.1| 1412|Homo sapiens densin-180-like protein... 91 4e-18
AF263744-1|AAF77048.1| 1371|Homo sapiens erbb2-interacting prote... 91 4e-18
AB033051-1|BAA86539.2| 1371|Homo sapiens KIAA1225 protein protein. 91 4e-18
AB016816-1|BAA74737.1| 1052|Homo sapiens MASL1 protein. 91 5e-18
AL391728-2|CAH73692.1| 1495|Homo sapiens leucine rich repeat con... 90 9e-18
AL391728-1|CAH73691.1| 1537|Homo sapiens leucine rich repeat con... 90 9e-18
AL359412-2|CAH74019.1| 1495|Homo sapiens leucine rich repeat con... 90 9e-18
AL359412-1|CAH74018.1| 1537|Homo sapiens leucine rich repeat con... 90 9e-18
AL158840-2|CAH70975.1| 1495|Homo sapiens leucine rich repeat con... 90 9e-18
AL158840-1|CAH70974.1| 1537|Homo sapiens leucine rich repeat con... 90 9e-18
AL157948-2|CAI22426.1| 1495|Homo sapiens leucine rich repeat con... 90 9e-18
AL157948-1|CAI22425.1| 1537|Homo sapiens leucine rich repeat con... 90 9e-18
AL117353-1|CAI23423.1| 1495|Homo sapiens leucine rich repeat con... 90 9e-18
AF434715-1|AAL28133.1| 1537|Homo sapiens densin-180 protein. 90 9e-18
L12535-1|AAA60292.1| 277|Homo sapiens RSU-1 protein. 87 8e-17
CR541840-1|CAG46639.1| 277|Homo sapiens RSU1 protein. 87 8e-17
CR536521-1|CAG38758.1| 277|Homo sapiens RSU1 protein. 87 8e-17
BC015644-1|AAH15644.1| 277|Homo sapiens Ras suppressor protein ... 87 8e-17
BC008691-1|AAH08691.1| 277|Homo sapiens RSU1 protein protein. 87 8e-17
BC005993-1|AAH05993.1| 277|Homo sapiens Ras suppressor protein ... 87 8e-17
AL365215-3|CAH73633.1| 277|Homo sapiens Ras suppressor protein ... 87 8e-17
U80184-1|AAC02796.1| 1269|Homo sapiens FLII protein. 86 1e-16
U01184-1|AAC03568.1| 1268|Homo sapiens flightless-I homolog prot... 86 1e-16
BC025300-1|AAH25300.1| 1269|Homo sapiens flightless I homolog (D... 86 1e-16
BC018529-1|AAH18529.3| 683|Homo sapiens leucine-rich repeats an... 86 1e-16
AF053356-12|AAC78793.1| 832|Homo sapiens leucin rich neuronal p... 86 1e-16
BC107898-1|AAI07899.1| 280|Homo sapiens RSU1 protein protein. 85 3e-16
BC009239-1|AAH09239.1| 723|Homo sapiens leucine rich repeat and... 84 4e-16
AY358830-1|AAQ89189.1| 723|Homo sapiens leucine-rich protein pr... 84 4e-16
AL445222-17|CAH72931.1| 696|Homo sapiens leucine rich repeat an... 84 4e-16
AL445222-16|CAH72930.1| 723|Homo sapiens leucine rich repeat an... 84 4e-16
AK091589-1|BAC03703.1| 723|Homo sapiens protein ( Homo sapiens ... 84 4e-16
AK056203-1|BAB71119.1| 696|Homo sapiens protein ( Homo sapiens ... 84 4e-16
AB208864-1|BAD92101.1| 1101|Homo sapiens flightless I homolog va... 83 8e-16
BC014904-1|AAH14904.1| 893|Homo sapiens leucine-rich repeats an... 83 1e-15
AK001637-1|BAA91801.1| 183|Homo sapiens protein ( Homo sapiens ... 83 1e-15
AF274972-1|AAG13461.1| 910|Homo sapiens PIDD protein. 83 1e-15
BC051322-1|AAH51322.1| 810|Homo sapiens leucine rich repeat con... 82 2e-15
BC013757-1|AAH13757.1| 403|Homo sapiens LRRC58 protein protein. 82 2e-15
AY358286-1|AAQ88653.1| 546|Homo sapiens RQTI221 protein. 82 2e-15
AY143166-1|AAN18279.1| 810|Homo sapiens leucine-rich repeat-con... 82 2e-15
AL672142-1|CAI10839.1| 810|Homo sapiens leucine rich repeat con... 82 2e-15
AK074723-1|BAC11161.1| 546|Homo sapiens protein ( Homo sapiens ... 82 2e-15
AK027495-1|BAB55153.1| 474|Homo sapiens protein ( Homo sapiens ... 82 2e-15
AB037858-1|BAA92675.1| 811|Homo sapiens KIAA1437 protein protein. 82 2e-15
AY358137-1|AAQ88504.1| 255|Homo sapiens VKGE9338 protein. 82 2e-15
AK021896-1|BAB13929.1| 197|Homo sapiens protein ( Homo sapiens ... 81 3e-15
AL391728-3|CAH73693.1| 217|Homo sapiens leucine rich repeat con... 81 5e-15
AL359894-1|CAH73131.1| 217|Homo sapiens leucine rich repeat con... 81 5e-15
AL359412-3|CAH74020.1| 217|Homo sapiens leucine rich repeat con... 81 5e-15
AL117353-2|CAI23424.1| 217|Homo sapiens leucine rich repeat con... 81 5e-15
AF498274-1|AAP06801.1| 217|Homo sapiens densin-180 like protein... 81 5e-15
BC029118-1|AAH29118.1| 371|Homo sapiens leucine rich repeat con... 80 7e-15
AK223440-1|BAD97160.1| 371|Homo sapiens leucine rich repeat con... 80 7e-15
AK057808-1|BAB71585.1| 371|Homo sapiens protein ( Homo sapiens ... 80 7e-15
AK001199-1|BAA91549.1| 221|Homo sapiens protein ( Homo sapiens ... 80 7e-15
BC047306-1|AAH47306.1| 367|Homo sapiens leucine rich repeat con... 79 1e-14
BC009613-1|AAH09613.1| 335|Homo sapiens leucine rich repeat con... 79 1e-14
AY358131-1|AAQ88498.1| 335|Homo sapiens densin hlg protein. 79 1e-14
AY358082-1|AAQ88449.1| 312|Homo sapiens ASEL436 protein. 79 1e-14
AL445928-6|CAH72254.1| 339|Homo sapiens leucine rich repeat con... 79 1e-14
AL445928-5|CAH72253.1| 335|Homo sapiens leucine rich repeat con... 79 1e-14
AJ308569-1|CAC33442.1| 371|Homo sapiens leucine-rich repeat-con... 79 1e-14
AF229178-1|AAF69491.1| 753|Homo sapiens leucine rich repeat and... 79 2e-14
BC036722-1|AAH36722.1| 261|Homo sapiens leucine rich repeat con... 79 2e-14
AK000338-1|BAA91094.1| 384|Homo sapiens protein ( Homo sapiens ... 79 2e-14
BC108252-1|AAI08253.1| 532|Homo sapiens LRRC8E protein protein. 77 7e-14
BC070089-1|AAH70089.1| 796|Homo sapiens leucine rich repeat con... 77 7e-14
BC022216-1|AAH22216.2| 592|Homo sapiens LRRC8E protein protein. 77 7e-14
AL834474-1|CAD39133.1| 622|Homo sapiens hypothetical protein pr... 77 7e-14
AK027073-1|BAB15648.1| 444|Homo sapiens protein ( Homo sapiens ... 77 7e-14
BC033039-1|AAH33039.1| 927|Homo sapiens LGR4 protein protein. 77 9e-14
AB209743-1|BAD92980.1| 1032|Homo sapiens Leucine-rich repeat-con... 77 9e-14
BC106893-1|AAI06894.1| 250|Homo sapiens LRRC10 protein protein. 76 2e-13
BC106892-1|AAI06893.1| 249|Homo sapiens LRRC10 protein protein. 76 2e-13
BC090881-1|AAH90881.1| 277|Homo sapiens leucine rich repeat con... 76 2e-13
AK123908-1|BAC85724.1| 250|Homo sapiens protein ( Homo sapiens ... 76 2e-13
AF346711-1|AAK31153.1| 951|Homo sapiens G-protein couple recept... 75 3e-13
AF257182-1|AAF68989.1| 951|Homo sapiens G-protein-coupled recep... 75 3e-13
AY358112-1|AAQ88479.1| 802|Homo sapiens ITLT6413 protein. 74 5e-13
BC139921-1|AAI39922.1| 414|Homo sapiens peptidylprolyl isomeras... 74 6e-13
AY052405-1|AAL11430.1| 414|Homo sapiens 4-1BB-mediated signalin... 74 6e-13
D86984-1|BAA13220.2| 823|Homo sapiens KIAA0231 protein protein. 73 8e-13
BC060782-1|AAH60782.1| 803|Homo sapiens LRRC8B protein protein. 73 8e-13
BC030607-1|AAH30607.1| 803|Homo sapiens leucine rich repeat con... 73 8e-13
AL589786-1|CAH70721.1| 612|Homo sapiens leucine-rich repeats an... 73 8e-13
AL445164-1|CAI43033.1| 612|Homo sapiens leucine-rich repeats an... 73 8e-13
AL121878-2|CAI42077.1| 612|Homo sapiens leucine-rich repeats an... 73 8e-13
AF385436-1|AAM43837.1| 803|Homo sapiens T-cell activation leuci... 73 8e-13
X72913-1|CAA51418.1| 376|Homo sapiens fibromodulin protein. 73 1e-12
BC035281-1|AAH35281.1| 376|Homo sapiens fibromodulin protein. 73 1e-12
AL359837-1|CAH73821.1| 376|Homo sapiens fibromodulin protein. 73 1e-12
AL513211-2|CAI17359.1| 154|Homo sapiens leucine rich repeat con... 71 3e-12
X75546-1|CAA53233.1| 376|Homo sapiens fibromodulin protein. 71 4e-12
BC126277-1|AAI26278.1| 1205|Homo sapiens PH domain and leucine r... 71 4e-12
BC057786-1|AAH57786.1| 512|Homo sapiens podocan-like 1 protein. 71 4e-12
BC052279-1|AAH52279.1| 307|Homo sapiens leucine rich repeat con... 71 4e-12
BC017168-1|AAH17168.1| 307|Homo sapiens leucine rich repeat con... 71 4e-12
BC014927-1|AAH14927.3| 1205|Homo sapiens PH domain and leucine r... 71 4e-12
AL365215-2|CAH73632.1| 224|Homo sapiens Ras suppressor protein ... 71 4e-12
AK001924-1|BAA91980.1| 721|Homo sapiens protein ( Homo sapiens ... 71 4e-12
AB011178-1|BAA25532.2| 1369|Homo sapiens KIAA0606 protein protein. 71 4e-12
BC113973-1|AAI13974.1| 803|Homo sapiens factor for adipocyte di... 70 8e-12
BC030608-1|AAH30608.1| 661|Homo sapiens podocan protein. 70 8e-12
BC028292-1|AAH28292.1| 402|Homo sapiens PODN protein protein. 70 8e-12
AY358294-1|AAQ88661.1| 642|Homo sapiens EGEE293 protein. 70 8e-12
AB081509-1|BAB86303.1| 803|Homo sapiens AD158 protein. 70 8e-12
AY313607-1|AAP79898.1| 613|Homo sapiens podocan protein protein. 70 1e-11
AL445183-5|CAH72592.1| 642|Homo sapiens podocan protein. 70 1e-11
AL445183-4|CAH72591.1| 661|Homo sapiens podocan protein. 70 1e-11
Z23091-1|CAA80637.1| 560|Homo sapiens platelet glycoprotein V p... 69 2e-11
L11238-1|AAA03069.1| 560|Homo sapiens platelet membrane glycopr... 69 2e-11
U41344-1|AAC18782.1| 382|Homo sapiens prolargin protein. 67 5e-11
U29089-1|AAC50230.1| 382|Homo sapiens proline- arginine-rich en... 67 5e-11
CR542270-1|CAG47066.1| 382|Homo sapiens PRELP protein. 67 5e-11
CR541787-1|CAG46586.1| 382|Homo sapiens PRELP protein. 67 5e-11
BC042334-1|AAH42334.2| 545|Homo sapiens carboxypeptidase N, pol... 67 5e-11
BC032498-1|AAH32498.1| 382|Homo sapiens proline/arginine-rich e... 67 5e-11
AL391817-1|CAI17033.1| 382|Homo sapiens proline/arginine-rich e... 67 5e-11
J05158-1|AAA51921.2| 545|Homo sapiens carboxypeptidase N precur... 67 7e-11
BC031569-1|AAH31569.2| 545|Homo sapiens carboxypeptidase N, pol... 67 7e-11
BC007634-1|AAH07634.1| 580|Homo sapiens LRCH4 protein protein. 67 7e-11
BC096326-1|AAH96326.1| 883|Homo sapiens LGR5 protein protein. 66 9e-11
BC096325-1|AAH96325.1| 883|Homo sapiens LGR5 protein protein. 66 9e-11
AL022344-3|CAI23616.1| 146|Homo sapiens novel protein similar t... 66 9e-11
BC129927-1|AAI29928.1| 1323|Homo sapiens PH domain and leucine r... 66 2e-10
BC035267-1|AAH35267.1| 723|Homo sapiens PHLPPL protein protein. 65 2e-10
BC099650-1|AAH99650.1| 907|Homo sapiens leucine-rich repeat-con... 64 4e-10
BC096324-1|AAH96324.1| 907|Homo sapiens leucine-rich repeat-con... 64 4e-10
AF062006-1|AAC28019.1| 907|Homo sapiens orphan G protein-couple... 64 4e-10
AB071037-1|BAB84587.1| 581|Homo sapiens Lib protein. 64 5e-10
BC101065-1|AAI01066.1| 581|Homo sapiens LRRC15 protein protein. 64 7e-10
BC101064-1|AAI01065.1| 581|Homo sapiens leucine rich repeat con... 64 7e-10
BC046356-1|AAH46356.1| 421|Homo sapiens osteomodulin protein. 62 2e-09
AY358872-1|AAQ89231.1| 421|Homo sapiens OMD protein. 62 2e-09
AL137848-4|CAI16696.1| 421|Homo sapiens osteomodulin protein. 62 2e-09
AB009589-1|BAA23982.1| 421|Homo sapiens Osteomodulin protein. 62 2e-09
AB000114-1|BAA19055.1| 421|Homo sapiens osteomodulin protein. 62 2e-09
J04599-1|AAA36009.1| 368|Homo sapiens protein ( Human hPGI mRNA... 62 2e-09
BT007323-1|AAP35987.1| 368|Homo sapiens biglycan protein. 62 2e-09
BC004244-1|AAH04244.1| 368|Homo sapiens biglycan protein. 62 2e-09
BC002416-1|AAH02416.1| 368|Homo sapiens biglycan protein. 62 2e-09
AK223302-1|BAD97022.1| 368|Homo sapiens biglycan preproprotein ... 62 2e-09
AK124678-1|BAC85924.1| 423|Homo sapiens protein ( Homo sapiens ... 62 2e-09
AF061444-1|AAC77911.1| 907|Homo sapiens G protein-coupled recep... 62 2e-09
AB023148-1|BAA76775.2| 1258|Homo sapiens KIAA0931 protein protein. 62 2e-09
AL356953-5|CAI15931.1| 232|Homo sapiens leucine-rich repeat-con... 61 4e-09
AB033020-1|BAA86508.1| 575|Homo sapiens KIAA1194 protein protein. 61 4e-09
BC113717-1|AAI13718.1| 581|Homo sapiens leucine rich repeat tra... 60 6e-09
BC113715-1|AAI13716.1| 581|Homo sapiens leucine rich repeat tra... 60 6e-09
BC111492-1|AAI11493.1| 581|Homo sapiens leucine rich repeat tra... 60 6e-09
BC040879-1|AAH40879.1| 493|Homo sapiens adhesion molecule with ... 60 6e-09
AY358315-1|AAQ88681.1| 513|Homo sapiens GFNV803 protein. 60 6e-09
AY237007-1|AAO48948.1| 493|Homo sapiens transmembrane protein A... 60 6e-09
AY182028-1|AAO67549.1| 513|Homo sapiens leucine-rich repeat tra... 60 6e-09
AL355145-6|CAI22942.1| 493|Homo sapiens adhesion molecule with ... 60 6e-09
AK222484-1|BAD96204.1| 368|Homo sapiens biglycan preproprotein ... 60 6e-09
AB032989-1|BAA86477.1| 437|Homo sapiens KIAA1163 protein protein. 60 6e-09
X57436-1|CAA40684.1| 440|Homo sapiens oligodentrocyte-myelin gl... 60 8e-09
X51694-1|CAA35991.1| 433|Homo sapiens oligodendrocyte-myelin gl... 60 8e-09
M63623-1|AAA59970.1| 440|Homo sapiens oligodendrocyte-myelin gl... 60 8e-09
BC126171-1|AAI26172.1| 1119|Homo sapiens leucine-rich repeats an... 60 8e-09
BC126169-1|AAI26170.1| 1119|Homo sapiens leucine-rich repeats an... 60 8e-09
BC082244-1|AAH82244.1| 465|Homo sapiens PHLPP protein protein. 60 8e-09
BC045113-1|AAH45113.1| 522|Homo sapiens LRRTM1 protein protein. 60 8e-09
BC018050-1|AAH18050.1| 440|Homo sapiens oligodendrocyte myelin ... 60 8e-09
AY505340-1|AAR98629.1| 1119|Homo sapiens leucine-rich and immuno... 60 8e-09
AY358310-1|AAQ88677.1| 522|Homo sapiens DFLL675 protein. 60 8e-09
AY358295-1|AAQ88662.1| 1059|Homo sapiens SAPS287 protein. 60 8e-09
AY358288-1|AAQ88655.1| 1119|Homo sapiens SAPS287 protein. 60 8e-09
AY182024-1|AAO67545.1| 522|Homo sapiens leucine-rich repeat tra... 60 8e-09
AK222663-1|BAD96383.1| 440|Homo sapiens oligodendrocyte myelin ... 60 8e-09
AK056644-1|BAB71240.1| 522|Homo sapiens protein ( Homo sapiens ... 60 8e-09
BC031301-1|AAH31301.1| 583|Homo sapiens leucine rich repeat con... 60 1e-08
AL365330-3|CAI42528.1| 583|Homo sapiens leucine rich repeat con... 60 1e-08
M22403-1|AAA52596.1| 626|Homo sapiens platelet membrane glycopr... 59 1e-08
J02940-1|AAA52595.1| 626|Homo sapiens GP1BA protein. 59 1e-08
BC047905-1|AAH47905.2| 915|Homo sapiens leucine-rich repeat-con... 59 1e-08
BC027955-1|AAH27955.1| 626|Homo sapiens glycoprotein Ib (platel... 59 1e-08
AY730707-1|AAU44786.1| 1093|Homo sapiens leucine-rich repeat pro... 59 1e-08
AY358119-1|AAQ88486.1| 915|Homo sapiens gonadotropin receptor p... 59 1e-08
AM709890-1|CAM97225.1| 639|Homo sapiens platelet glycoprotein I... 59 1e-08
AL356953-3|CAI15929.1| 915|Homo sapiens leucine-rich repeat-con... 59 1e-08
AL356953-1|CAI15927.1| 967|Homo sapiens leucine-rich repeat-con... 59 1e-08
AF395009-1|AAK71325.1| 626|Homo sapiens glycoprotein Ib (platel... 59 1e-08
AB086948-1|BAC10305.1| 626|Homo sapiens platelet glycoprotein I... 59 1e-08
AB049405-1|BAB39854.1| 928|Homo sapiens VTS20631 protein. 59 1e-08
BX537976-1|CAD97940.1| 693|Homo sapiens hypothetical protein pr... 59 2e-08
BC146759-1|AAI46760.1| 1523|Homo sapiens slit homolog 3 (Drosoph... 59 2e-08
BC117190-1|AAI17191.1| 1529|Homo sapiens slit homolog 2 (Drosoph... 59 2e-08
BC107493-1|AAI07494.1| 699|Homo sapiens extracellular matrix pr... 59 2e-08
AY358884-1|AAQ89243.1| 1523|Homo sapiens SLIT3 protein. 59 2e-08
AL157827-4|CAI12589.1| 699|Homo sapiens extracellular matrix pr... 59 2e-08
AL137848-1|CAI16693.1| 699|Homo sapiens extracellular matrix pr... 59 2e-08
AF133270-1|AAD25539.1| 1525|Homo sapiens SLIT2 protein. 59 2e-08
AF055585-1|AAD04309.1| 1521|Homo sapiens neurogenic extracellula... 59 2e-08
AB017169-1|BAA35186.1| 1523|Homo sapiens Slit-3 protein protein. 59 2e-08
AB017168-1|BAA35185.1| 1529|Homo sapiens Slit-2 protein protein. 59 2e-08
AB011792-1|BAA33958.1| 699|Homo sapiens extracellular matrix pr... 59 2e-08
AB011538-1|BAA32466.2| 1559|Homo sapiens MEGF5 protein. 59 2e-08
DQ013130-1|AAY67799.1| 2014|Homo sapiens leucine-rich repeat kin... 58 3e-08
BC025681-1|AAH25681.1| 605|Homo sapiens insulin-like growth fac... 58 3e-08
AK058188-1|BAB71707.1| 475|Homo sapiens protein ( Homo sapiens ... 58 3e-08
AB038516-1|BAB12038.1| 626|Homo sapiens platelet glycoprotein I... 58 3e-08
M86826-1|AAA36047.1| 605|Homo sapiens insulin-like growth facto... 58 3e-08
M65153-1|AAA52287.1| 394|Homo sapiens biglycan protein. 58 3e-08
BC113617-1|AAI13618.1| 757|Homo sapiens relaxin/insulin-like fa... 58 3e-08
BC112142-1|AAI12143.1| 757|Homo sapiens leucine-rich repeat-con... 58 3e-08
BC030276-1|AAH30276.1| 529|Homo sapiens LOC220416 protein protein. 58 3e-08
AY899850-1|AAX85198.1| 724|Homo sapiens LGR7.10 protein. 58 3e-08
AY899849-1|AAX85197.1| 709|Homo sapiens LGR7.2 protein. 58 3e-08
AL139801-5|CAM14704.1| 506|Homo sapiens similar to Leucine-rich... 58 3e-08
AL137141-1|CAI12166.2| 506|Homo sapiens similar to Leucine-rich... 58 3e-08
AL031724-2|CAC36078.1| 605|Homo sapiens C447E6.2 (insulin-like ... 58 3e-08
AF192554-1|AAF06774.1| 605|Homo sapiens acid-labile subunit pro... 58 3e-08
AF190500-1|AAG17167.1| 757|Homo sapiens leucine-rich repeat-con... 58 3e-08
AC108017-1|AAY41039.1| 260|Homo sapiens unknown protein. 58 3e-08
BC117180-1|AAI17181.1| 2527|Homo sapiens leucine-rich repeat kin... 57 6e-08
BC070198-1|AAH70198.1| 347|Homo sapiens leucine-rich alpha-2-gl... 57 6e-08
BC034389-1|AAH34389.1| 347|Homo sapiens leucine-rich alpha-2-gl... 57 6e-08
AY792511-1|AAV63975.1| 2527|Homo sapiens leucine-rich repeat kin... 57 6e-08
AK127729-1|BAC87105.1| 870|Homo sapiens protein ( Homo sapiens ... 57 6e-08
AF403428-1|AAK95527.1| 347|Homo sapiens leucine-rich alpha-2-gl... 57 6e-08
AB073607-1|BAD38644.1| 347|Homo sapiens leucine-rich alpha-2-gl... 57 6e-08
BC101073-1|AAI01074.1| 841|Homo sapiens SLIT and NTRK-like fami... 57 8e-08
BC101072-1|AAI01073.1| 841|Homo sapiens SLIT and NTRK-like fami... 57 8e-08
BC101071-1|AAI01072.1| 841|Homo sapiens SLIT and NTRK-like fami... 57 8e-08
BC101070-1|AAI01071.1| 841|Homo sapiens SLIT and NTRK-like fami... 57 8e-08
AK026427-1|BAB15480.1| 440|Homo sapiens protein ( Homo sapiens ... 57 8e-08
BC105958-1|AAI05959.1| 677|Homo sapiens ECM2 protein protein. 56 1e-07
AY358733-1|AAQ89095.1| 622|Homo sapiens CGLQ1891 protein. 56 1e-07
AY280614-1|AAP36706.1| 622|Homo sapiens synleurin protein. 56 1e-07
AK123022-1|BAC85517.1| 622|Homo sapiens protein ( Homo sapiens ... 56 1e-07
BC035133-1|AAH35133.1| 708|Homo sapiens leucine rich repeat neu... 56 1e-07
CR457397-1|CAG33678.1| 708|Homo sapiens LRRN3 protein. 56 2e-07
BC150568-1|AAI50569.1| 370|Homo sapiens leucine-rich repeats an... 56 2e-07
BC024001-1|AAH24001.1| 184|Homo sapiens leucine rich repeat con... 56 2e-07
AY358318-1|AAQ88684.1| 184|Homo sapiens LKKM2429 protein. 56 2e-07
AY358280-1|AAQ88647.1| 708|Homo sapiens LRRN3 protein. 56 2e-07
AL355138-5|CAI12602.1| 175|Homo sapiens leucine rich repeat con... 56 2e-07
AL355138-3|CAI12600.1| 184|Homo sapiens leucine rich repeat con... 56 2e-07
AK095610-1|BAC04589.1| 370|Homo sapiens protein ( Homo sapiens ... 56 2e-07
AK094734-1|BAC04409.1| 184|Homo sapiens protein ( Homo sapiens ... 56 2e-07
AK001991-1|BAA92025.1| 273|Homo sapiens protein ( Homo sapiens ... 56 2e-07
AF134481-1|AAP97258.1| 708|Homo sapiens leucine-rich repeat pro... 56 2e-07
AB060967-1|BAB47184.1| 708|Homo sapiens neuronal leucine-rich r... 56 2e-07
BC117370-1|AAI17371.1| 1065|Homo sapiens leucine-rich repeats an... 55 2e-07
BC117368-1|AAI17369.1| 1065|Homo sapiens leucine-rich repeats an... 55 2e-07
BC080586-1|AAH80586.1| 743|Homo sapiens MXRA5 protein protein. 55 2e-07
BC064986-1|AAH64986.1| 743|Homo sapiens MXRA5 protein protein. 55 2e-07
BC011846-1|AAH11846.1| 743|Homo sapiens MXRA5 protein protein. 55 2e-07
AL357055-1|CAH73254.1| 1065|Homo sapiens leucine-rich repeats an... 55 2e-07
AB018349-1|BAA34526.2| 1073|Homo sapiens KIAA0806 protein protein. 55 2e-07
BC026112-1|AAH26112.1| 116|Homo sapiens hypothetical protein LO... 55 3e-07
AY899851-1|AAX85199.1| 730|Homo sapiens LGR8.1 protein. 55 3e-07
AF075240-1|AAD19336.1| 850|Homo sapiens SLIT1 protein protein. 55 3e-07
BC146761-1|AAI46762.1| 1534|Homo sapiens slit homolog 1 (Drosoph... 54 4e-07
BC117276-1|AAI17277.1| 420|Homo sapiens reticulon 4 receptor-li... 54 4e-07
BC113673-1|AAI13674.1| 420|Homo sapiens reticulon 4 receptor-li... 54 4e-07
AY250221-1|AAP82838.1| 420|Homo sapiens nogo receptor-like 3 pr... 54 4e-07
AL512424-5|CAI14258.1| 1534|Homo sapiens slit homolog 1 (Drosoph... 54 4e-07
AL512424-4|CAI14259.1| 1461|Homo sapiens slit homolog 1 (Drosoph... 54 4e-07
AL442123-4|CAH70918.1| 1534|Homo sapiens slit homolog 1 (Drosoph... 54 4e-07
AL442123-3|CAH70917.1| 1461|Homo sapiens slit homolog 1 (Drosoph... 54 4e-07
AF532858-1|AAP21835.1| 420|Homo sapiens Nogo-66 receptor homolo... 54 4e-07
AB017167-1|BAA35184.1| 1534|Homo sapiens Slit-1 protein protein. 54 4e-07
AB011537-1|BAA32465.3| 1618|Homo sapiens MEGF4 protein. 54 4e-07
AF245505-1|AAF86402.1| 2828|Homo sapiens adlican protein. 54 5e-07
BC040986-1|AAH40986.1| 837|Homo sapiens SLIT and NTRK-like fami... 54 7e-07
AL713693-1|CAD28493.1| 689|Homo sapiens hypothetical protein pr... 54 7e-07
AL080239-3|CAI41650.1| 837|Homo sapiens novel protein protein. 54 7e-07
AK057619-1|BAB71535.1| 469|Homo sapiens protein ( Homo sapiens ... 54 7e-07
DQ084201-1|AAY86708.1| 640|Homo sapiens netrin-G1 ligand splice... 53 9e-07
BC041374-1|AAH41374.3| 640|Homo sapiens LRRC4C protein protein. 53 9e-07
BC032667-1|AAH32667.1| 352|Homo sapiens keratocan protein. 53 9e-07
AY358293-1|AAQ88660.1| 640|Homo sapiens LNKM292 protein. 53 9e-07
AF205403-1|AAF69126.1| 352|Homo sapiens keratocan protein. 53 9e-07
AF065988-1|AAC17741.1| 352|Homo sapiens keratocan protein. 53 9e-07
AF063301-1|AAC16390.1| 352|Homo sapiens keratan sulfate proteog... 53 9e-07
AB046800-1|BAB13406.1| 640|Homo sapiens KIAA1580 protein protein. 53 9e-07
U93091-1|AAC80227.1| 839|Homo sapiens Toll protein homolog prot... 53 1e-06
U88880-1|AAC34135.1| 799|Homo sapiens Toll-like receptor 4 prot... 53 1e-06
BC117422-1|AAI17423.1| 839|Homo sapiens toll-like receptor 4 pr... 53 1e-06
AL160272-2|CAH72619.1| 799|Homo sapiens toll-like receptor 4 pr... 53 1e-06
AL160272-1|CAH72618.1| 839|Homo sapiens toll-like receptor 4 pr... 53 1e-06
AK127177-1|BAC86870.1| 279|Homo sapiens protein ( Homo sapiens ... 53 1e-06
AK027100-1|BAB15657.1| 363|Homo sapiens protein ( Homo sapiens ... 53 1e-06
AF177765-1|AAF05316.1| 839|Homo sapiens toll-like receptor 4 pr... 53 1e-06
AF172171-1|AAF89753.1| 839|Homo sapiens toll-like receptor 4 pr... 53 1e-06
BC130290-1|AAI30291.1| 660|Homo sapiens fibronectin leucine ric... 52 2e-06
BC126249-1|AAI26250.1| 660|Homo sapiens fibronectin leucine ric... 52 2e-06
BC104899-1|AAI04900.1| 825|Homo sapiens leucine-rich repeats an... 52 2e-06
BC104897-1|AAI04898.1| 825|Homo sapiens leucine-rich repeats an... 52 2e-06
BC033651-1|AAH33651.1| 1049|Homo sapiens toll-like receptor 7 pr... 52 2e-06
AY358292-1|AAQ88659.1| 1049|Homo sapiens TLR7 protein. 52 2e-06
AY358287-1|AAQ88654.1| 660|Homo sapiens FLRT2 protein. 52 2e-06
AK057348-1|BAB71441.1| 825|Homo sapiens protein ( Homo sapiens ... 52 2e-06
AF240467-1|AAF60188.1| 1049|Homo sapiens toll-like receptor 7 pr... 52 2e-06
AF169676-1|AAF28460.1| 660|Homo sapiens leucine-rich repeat tra... 52 2e-06
AB007865-1|BAA23701.2| 706|Homo sapiens KIAA0405 protein. 52 2e-06
AY358114-1|AAQ88481.1| 606|Homo sapiens Tango hlg protein. 52 2e-06
AL353746-1|CAC22713.1| 606|Homo sapiens leucine rich repeat and... 52 2e-06
AK056372-1|BAB71167.1| 606|Homo sapiens protein ( Homo sapiens ... 52 2e-06
U88879-1|AAC34134.1| 904|Homo sapiens Toll-like receptor 3 prot... 52 3e-06
DQ445682-1|ABE01399.1| 904|Homo sapiens Toll-like receptor 3 is... 52 3e-06
DQ084202-1|AAY86709.1| 640|Homo sapiens netrin-G1 ligand splice... 52 3e-06
BC103509-1|AAI03510.1| 958|Homo sapiens SLIT and NTRK-like fami... 52 3e-06
BC098287-1|AAH98287.1| 958|Homo sapiens SLIT and NTRK-like fami... 52 3e-06
BC098106-1|AAH98106.1| 958|Homo sapiens SLIT and NTRK-like fami... 52 3e-06
BC096335-1|AAH96335.1| 904|Homo sapiens toll-like receptor 3 pr... 52 3e-06
BC096334-1|AAH96334.1| 904|Homo sapiens toll-like receptor 3 pr... 52 3e-06
BC096333-1|AAH96333.1| 904|Homo sapiens toll-like receptor 3 pr... 52 3e-06
BC094737-1|AAH94737.1| 904|Homo sapiens toll-like receptor 3 pr... 52 3e-06
BC059372-1|AAH59372.1| 870|Homo sapiens TLR3 protein protein. 52 3e-06
AL603883-1|CAH73026.1| 958|Homo sapiens SLIT and NTRK-like fami... 52 3e-06
AB020725-1|BAA74941.1| 966|Homo sapiens KIAA0918 protein protein. 52 3e-06
BC074741-1|AAH74741.1| 345|Homo sapiens leucine-rich repeats an... 51 4e-06
BC037982-1|AAH37982.1| 685|Homo sapiens leucine rich repeat con... 51 4e-06
AL356953-4|CAI15930.1| 828|Homo sapiens leucine-rich repeat-con... 51 4e-06
AK000163-1|BAA90984.1| 685|Homo sapiens protein ( Homo sapiens ... 51 4e-06
AF225421-1|AAG09723.1| 345|Homo sapiens HT017 protein. 51 4e-06
AF190501-1|AAG17168.1| 828|Homo sapiens leucine-rich repeat-con... 51 4e-06
U21128-1|AAA91639.1| 338|Homo sapiens lumican protein. 51 5e-06
U18728-1|AAA85268.1| 338|Homo sapiens lumican protein. 51 5e-06
BT006707-1|AAP35353.1| 338|Homo sapiens lumican protein. 51 5e-06
BC110058-1|AAI10059.1| 518|Homo sapiens leucine rich repeat tra... 51 5e-06
BC099738-1|AAH99738.1| 518|Homo sapiens leucine rich repeat tra... 51 5e-06
BC098301-1|AAH98301.1| 519|Homo sapiens LRRTM4 protein protein. 51 5e-06
BC098267-1|AAH98267.1| 519|Homo sapiens LRRTM4 protein protein. 51 5e-06
BC035997-1|AAH35997.1| 338|Homo sapiens lumican protein. 51 5e-06
BC007038-1|AAH07038.1| 338|Homo sapiens lumican protein. 51 5e-06
AY358324-1|AAQ88690.1| 590|Homo sapiens GFHL3075 protein. 51 5e-06
AY182030-1|AAO67551.1| 518|Homo sapiens leucine-rich repeat tra... 51 5e-06
AK126961-1|BAC86764.1| 518|Homo sapiens protein ( Homo sapiens ... 51 5e-06
U88878-1|AAC34133.1| 784|Homo sapiens Toll-like receptor 2 prot... 50 7e-06
BC033756-1|AAH33756.1| 784|Homo sapiens TLR2 protein protein. 50 7e-06
AF502291-1|AAM23001.1| 586|Homo sapiens toll-like receptor 2 pr... 50 7e-06
AF051152-1|AAC34377.1| 784|Homo sapiens Toll/interleukin-1 rece... 50 7e-06
Z24680-1|CAA80847.1| 662|Homo sapiens garp protein. 50 9e-06
BC070079-1|AAH70079.1| 662|Homo sapiens LRRC32 protein protein. 50 9e-06
BC068590-1|AAH68590.1| 778|Homo sapiens LOC150356 protein protein. 50 9e-06
BC052210-1|AAH52210.2| 552|Homo sapiens LRRC32 protein protein. 50 9e-06
BC018370-1|AAH18370.1| 674|Homo sapiens fibronectin leucine ric... 50 9e-06
AY358308-1|AAQ88675.1| 674|Homo sapiens FLRT1 protein. 50 9e-06
AL035681-1|CAI22653.1| 762|Homo sapiens protein ( Human DNA seq... 50 9e-06
AF169675-1|AAF28459.1| 674|Homo sapiens leucine-rich repeat tra... 50 9e-06
BC040188-1|AAH40188.1| 692|Homo sapiens LOC150356 protein protein. 50 1e-05
BC024009-1|AAH24009.3| 725|Homo sapiens leucine rich repeat con... 50 1e-05
AL122074-1|CAB59249.1| 333|Homo sapiens hypothetical protein pr... 50 1e-05
AK057238-1|BAB71392.1| 418|Homo sapiens protein ( Homo sapiens ... 50 1e-05
AK001706-1|BAA91849.1| 184|Homo sapiens protein ( Homo sapiens ... 50 1e-05
AF245702-1|AAF78035.1| 1049|Homo sapiens toll-like receptor 7 pr... 50 1e-05
D83597-1|BAA12019.1| 661|Homo sapiens RP105 protein. 49 2e-05
BC109070-1|AAI09071.1| 661|Homo sapiens CD180 molecule protein. 49 2e-05
BC109069-1|AAI09070.1| 661|Homo sapiens CD180 molecule protein. 49 2e-05
BC068558-1|AAH68558.1| 614|Homo sapiens LINGO1 protein protein. 49 2e-05
U61232-1|AAB17538.1| 527|Homo sapiens cofactor E protein. 49 2e-05
BT007086-1|AAP35749.1| 527|Homo sapiens tubulin-specific chaper... 49 2e-05
BC011057-1|AAH11057.2| 620|Homo sapiens leucine rich repeat and... 49 2e-05
BC008654-1|AAH08654.1| 527|Homo sapiens tubulin folding cofacto... 49 2e-05
AY324323-1|AAQ97218.1| 479|Homo sapiens leucine-rich repeat neu... 49 2e-05
AY324320-1|AAQ97216.1| 620|Homo sapiens leucine-rich repeat neu... 49 2e-05
AL834260-1|CAD38935.1| 577|Homo sapiens hypothetical protein pr... 49 2e-05
AL672237-1|CAH72080.1| 527|Homo sapiens tubulin folding cofacto... 49 2e-05
AL357556-2|CAI15017.1| 527|Homo sapiens tubulin folding cofacto... 49 2e-05
AL355138-4|CAI12601.1| 134|Homo sapiens leucine rich repeat con... 49 2e-05
BC030958-1|AAH30958.1| 322|Homo sapiens epiphycan protein. 48 3e-05
AK223177-1|BAD96897.1| 338|Homo sapiens lumican variant protein. 48 3e-05
AK172834-1|BAD18799.1| 459|Homo sapiens protein ( Homo sapiens ... 48 4e-05
BC063114-1|AAH63114.1| 384|Homo sapiens ASPN protein protein. 48 5e-05
AY358329-1|AAQ88695.1| 379|Homo sapiens ASPN protein. 48 5e-05
AY358290-1|AAQ88657.1| 713|Homo sapiens GAC1 protein. 48 5e-05
AY029191-1|AAK31800.1| 381|Homo sapiens periodontal ligament as... 48 5e-05
AL512306-1|CAI14096.1| 713|Homo sapiens leucine rich repeat neu... 48 5e-05
AL137848-6|CAI16697.1| 380|Homo sapiens asporin protein. 48 5e-05
AL137848-5|CAI16698.1| 243|Homo sapiens asporin protein. 48 5e-05
AK027359-1|BAB55060.1| 246|Homo sapiens protein ( Homo sapiens ... 48 5e-05
AF316824-1|AAK35161.1| 379|Homo sapiens asporin precursor protein. 48 5e-05
AF030435-1|AAC39792.1| 713|Homo sapiens glioma amplified on chr... 48 5e-05
AY273815-1|AAQ16156.1| 2623|Homo sapiens bone specific CMF608 pr... 47 6e-05
U88540-1|AAC34137.1| 786|Homo sapiens Toll-like receptor 1 prot... 47 8e-05
D13637-1|BAA02801.2| 789|Homo sapiens KIAA0012 protein. 47 8e-05
CR533562-1|CAG38593.1| 786|Homo sapiens TLR1 protein. 47 8e-05
BC109094-1|AAI09095.1| 786|Homo sapiens toll-like receptor 1 pr... 47 8e-05
BC109093-1|AAI09094.1| 786|Homo sapiens toll-like receptor 1 pr... 47 8e-05
BC089403-1|AAH89403.1| 786|Homo sapiens toll-like receptor 1 pr... 47 8e-05
BC068541-1|AAH68541.1| 713|Homo sapiens leucine rich repeat neu... 47 8e-05
BC034047-1|AAH34047.1| 713|Homo sapiens leucine rich repeat neu... 47 8e-05
BC020870-1|AAH20870.1| 649|Homo sapiens fibronectin leucine ric... 47 8e-05
AY358319-1|AAQ88685.1| 649|Homo sapiens FLRT3 protein. 47 8e-05
AL132826-1|CAB86687.1| 649|Homo sapiens fibronectin leucine ric... 47 8e-05
AK074909-1|BAC11284.1| 649|Homo sapiens protein ( Homo sapiens ... 47 8e-05
AK074883-1|BAC11265.1| 627|Homo sapiens protein ( Homo sapiens ... 47 8e-05
AK027694-1|BAB55303.1| 623|Homo sapiens protein ( Homo sapiens ... 47 8e-05
AK027297-1|BAB55023.1| 649|Homo sapiens protein ( Homo sapiens ... 47 8e-05
AF169677-1|AAF28461.1| 649|Homo sapiens leucine-rich repeat tra... 47 8e-05
AB040902-1|BAA95993.1| 662|Homo sapiens KIAA1469 protein protein. 47 8e-05
Y08200-1|CAA69382.1| 567|Homo sapiens rab geranylgeranyl transf... 46 1e-04
CR541797-1|CAG46596.1| 567|Homo sapiens RABGGTA protein. 46 1e-04
BC126156-1|AAI26157.1| 370|Homo sapiens leucine rich repeat con... 46 1e-04
BC109111-1|AAI09112.1| 811|Homo sapiens TLR10 protein protein. 46 1e-04
BC089406-1|AAH89406.1| 811|Homo sapiens TLR10 protein protein. 46 1e-04
BC068575-1|AAH68575.1| 673|Homo sapiens vasorin protein. 46 1e-04
BC040732-1|AAH40732.1| 269|Homo sapiens LRTM1 protein protein. 46 1e-04
BC013767-1|AAH13767.1| 601|Homo sapiens VASN protein protein. 46 1e-04
BC003093-1|AAH03093.1| 567|Homo sapiens Rab geranylgeranyltrans... 46 1e-04
AY358300-1|AAQ88667.1| 811|Homo sapiens TLR10 protein. 46 1e-04
AY358299-1|AAQ88666.1| 673|Homo sapiens CSRV314 protein. 46 1e-04
AY166584-1|AAO27704.1| 673|Homo sapiens vasorin protein. 46 1e-04
AK222987-1|BAD96707.1| 370|Homo sapiens leucine rich repeat con... 46 1e-04
AK024955-1|BAB15042.1| 370|Homo sapiens protein ( Homo sapiens ... 46 1e-04
AF296673-1|AAK26744.1| 811|Homo sapiens toll-like receptor 10 p... 46 1e-04
AF177766-1|AAF07823.1| 752|Homo sapiens human toll-like recepto... 46 1e-04
U59111-1|AAC50945.1| 322|Homo sapiens dermatan sulfate proteogl... 46 1e-04
BT007440-1|AAP36108.1| 353|Homo sapiens hypothetical protein, e... 46 1e-04
BC050097-1|AAH50097.1| 383|Homo sapiens LRRC27 protein protein. 46 1e-04
BC020975-1|AAH20975.1| 353|Homo sapiens tsukushin protein. 46 1e-04
AY358317-1|AAQ88683.1| 353|Homo sapiens E2IG4 protein. 46 1e-04
AY029183-1|AAK31796.1| 798|Homo sapiens SLIT1 isoform B protein. 46 1e-04
AL590105-6|CAI13017.1| 530|Homo sapiens novel protein protein. 46 1e-04
AL590105-5|CAI13016.1| 383|Homo sapiens novel protein protein. 46 1e-04
AL512424-3|CAI14257.1| 409|Homo sapiens slit homolog 1 (Drosoph... 46 1e-04
AL512424-1|CAI14255.1| 782|Homo sapiens slit homolog 1 (Drosoph... 46 1e-04
AK098652-1|BAC05366.1| 383|Homo sapiens protein ( Homo sapiens ... 46 1e-04
AF191019-1|AAF09483.1| 353|Homo sapiens E2IG4 protein. 46 1e-04
AB051461-1|BAB21765.1| 538|Homo sapiens KIAA1674 protein protein. 46 1e-04
BC071561-1|AAH71561.1| 1070|Homo sapiens LRIG1 protein protein. 46 2e-04
BC051738-1|AAH51738.1| 696|Homo sapiens SLIT and NTRK-like fami... 46 2e-04
AY358289-1|AAQ88656.1| 696|Homo sapiens LLWI233 protein. 46 2e-04
AL355481-1|CAC37488.1| 696|Homo sapiens SLIT and NTRK-like fami... 46 2e-04
AB067497-1|BAB67803.1| 760|Homo sapiens KIAA1910 protein protein. 46 2e-04
BC109112-1|AAI09113.1| 811|Homo sapiens TLR10 protein protein. 45 2e-04
BC044233-1|AAH44233.1| 692|Homo sapiens leucine rich repeat con... 45 2e-04
AY358322-1|AAQ88688.1| 692|Homo sapiens ELLP3030 protein. 45 2e-04
AL590105-8|CAI13019.1| 468|Homo sapiens novel protein protein. 45 2e-04
AL590105-7|CAI13018.1| 257|Homo sapiens novel protein protein. 45 2e-04
AK093250-1|BAC04108.1| 468|Homo sapiens protein ( Homo sapiens ... 45 2e-04
Y19205-1|CAC80724.1| 845|Homo sapiens SLITL1 protein. 45 3e-04
M14219-1|AAB00774.1| 359|Homo sapiens proteoglycan core protein... 45 3e-04
L01131-1|AAA52301.1| 347|Homo sapiens decorin protein. 45 3e-04
CR541946-1|CAG46744.1| 359|Homo sapiens DCN protein. 45 3e-04
CR407676-1|CAG28604.1| 359|Homo sapiens DCN protein. 45 3e-04
BX538330-1|CAD98099.1| 358|Homo sapiens hypothetical protein pr... 45 3e-04
BT019800-1|AAV38603.1| 359|Homo sapiens decorin protein. 45 3e-04
BC113012-1|AAI13013.1| 845|Homo sapiens SLIT and NTRK-like fami... 45 3e-04
BC113011-1|AAI13012.1| 845|Homo sapiens SLIT and NTRK-like fami... 45 3e-04
BC005322-1|AAH05322.1| 359|Homo sapiens decorin protein. 45 3e-04
AY358828-1|AAQ89187.1| 733|Homo sapiens LSGV9197 protein. 45 3e-04
AL109653-2|CAC18888.1| 845|Homo sapiens SLIT and NTRK-like fami... 45 3e-04
AL109653-1|CAI41645.1| 724|Homo sapiens SLIT and NTRK-like fami... 45 3e-04
AK128037-1|BAC87242.1| 1111|Homo sapiens protein ( Homo sapiens ... 45 3e-04
AK091015-1|BAC03566.1| 724|Homo sapiens protein ( Homo sapiens ... 45 3e-04
AF491944-1|AAL92176.1| 359|Homo sapiens decorin protein. 45 3e-04
AF138300-1|AAD44713.1| 359|Homo sapiens decorin variant A protein. 45 3e-04
AB058757-1|BAB47483.1| 572|Homo sapiens KIAA1854 protein protein. 45 3e-04
BC114621-1|AAI14622.1| 977|Homo sapiens SLIT and NTRK-like fami... 44 4e-04
AY358298-1|AAQ88665.1| 598|Homo sapiens CSRV314 protein. 44 4e-04
AL512424-2|CAI14256.1| 380|Homo sapiens slit homolog 1 (Drosoph... 44 4e-04
AB020655-1|BAA74871.2| 988|Homo sapiens KIAA0848 protein protein. 44 4e-04
BC101077-1|AAI01078.1| 1041|Homo sapiens toll-like receptor 8 pr... 44 6e-04
>BC058935-1|AAH58935.1| 239|Homo sapiens LRRC57 protein protein.
Length = 239
Score = 201 bits (491), Expect = 2e-51
Identities = 108/217 (49%), Positives = 143/217 (65%), Gaps = 1/217 (0%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDL-SKLKHLKQLNLDSNKLQALPES 564
+ D L E P D+ L LR +DLS NK+ LP L K LK L+L++NKL LP+
Sbjct: 21 LKDRGLTEFPADLQKLTSNLRTIDLSNNKIESLPPLLIGKFTLLKSLSLNNNKLTVLPDE 80
Query: 563 LINLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSH 384
+ NLKKLE L+++NN ++ LP L+ LK + S N+L A P Q+ L+ LDV+DLS
Sbjct: 81 ICNLKKLETLSLNNNHLRELPSTFGQLSALKTLSLSGNQLGALPPQLCSLRHLDVMDLSK 140
Query: 383 NKITEIPYGMSELYVIELNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRD 204
N+I IP + EL VIELNL+QN+IS I + PRLKILRL+ENCL L + S+L D
Sbjct: 141 NQIRSIPDSVGELQVIELNLNQNQISQISVKISCCPRLKILRLEENCLELSMLPQSILSD 200
Query: 203 SKIHTVSVDGNLFEPKQLAXLEGYNEYSERXTAMKKK 93
S+I ++V+GNLFE K+L LEGY++Y ER TA KKK
Sbjct: 201 SQICLLAVEGNLFEIKKLRELEGYDKYMERFTATKKK 237
>AK094131-1|BAC04294.1| 239|Homo sapiens (EC 2.4.1.101). protein.
Length = 239
Score = 201 bits (491), Expect = 2e-51
Identities = 108/217 (49%), Positives = 143/217 (65%), Gaps = 1/217 (0%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDL-SKLKHLKQLNLDSNKLQALPES 564
+ D L E P D+ L LR +DLS NK+ LP L K LK L+L++NKL LP+
Sbjct: 21 LKDRGLTEFPADLQKLTSNLRTIDLSNNKIESLPPLLIGKFTLLKSLSLNNNKLTVLPDE 80
Query: 563 LINLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSH 384
+ NLKKLE L+++NN ++ LP L+ LK + S N+L A P Q+ L+ LDV+DLS
Sbjct: 81 ICNLKKLETLSLNNNHLRELPSTFGQLSALKTLSLSGNQLGALPPQLCSLRHLDVMDLSK 140
Query: 383 NKITEIPYGMSELYVIELNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRD 204
N+I IP + EL VIELNL+QN+IS I + PRLKILRL+ENCL L + S+L D
Sbjct: 141 NQIRSIPDSVGELQVIELNLNQNQISQISVKISCCPRLKILRLEENCLELSMLPQSILSD 200
Query: 203 SKIHTVSVDGNLFEPKQLAXLEGYNEYSERXTAMKKK 93
S+I ++V+GNLFE K+L LEGY++Y ER TA KKK
Sbjct: 201 SQICLLAVEGNLFEIKKLRELEGYDKYMERFTATKKK 237
>AK094891-1|BAC04451.1| 239|Homo sapiens protein ( Homo sapiens
cDNA FLJ37572 fis, clone BRCOC2002751, weakly similar to
RAS SUPPRESSOR PROTEIN 1. ).
Length = 239
Score = 199 bits (486), Expect = 7e-51
Identities = 107/216 (49%), Positives = 142/216 (65%), Gaps = 1/216 (0%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDL-SKLKHLKQLNLDSNKLQALPES 564
+ D L E P D+ L LR +DLS NK+ LP L K LK L+L++NKL LP+
Sbjct: 21 LKDRGLTEFPADLQKLTSNLRTIDLSNNKIESLPPLLIGKFTLLKSLSLNNNKLTVLPDE 80
Query: 563 LINLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSH 384
+ NLKKLE L+++NN ++ LP L+ LK + S N+L A P Q+ L+ LDV+DLS
Sbjct: 81 ICNLKKLETLSLNNNHLRELPSTFGQLSALKTLSLSGNQLGALPPQLCSLRHLDVMDLSK 140
Query: 383 NKITEIPYGMSELYVIELNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRD 204
N+I IP + EL VIELNL+QN+IS I + PRLKILRL+ENCL L + S+L D
Sbjct: 141 NQIRSIPDSVGELQVIELNLNQNQISQISVKISCCPRLKILRLEENCLELSMLPQSILSD 200
Query: 203 SKIHTVSVDGNLFEPKQLAXLEGYNEYSERXTAMKK 96
S+I ++V+GNLFE K+L LEGY++Y ER TA KK
Sbjct: 201 SQICLLAVEGNLFEIKKLRELEGYDKYMERFTATKK 236
>BC007504-1|AAH07504.1| 712|Homo sapiens leucine-rich repeats and
calponin homology (CH) domain containing 3 protein.
Length = 712
Score = 104 bits (250), Expect = 3e-22
Identities = 70/189 (37%), Positives = 109/189 (57%), Gaps = 3/189 (1%)
Frame = -2
Query: 728 KLKEIPIDVFS--LCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLIN 555
KL+E P + L D R DLS+N+LS +P + L+ LNL N ++ +PE+++N
Sbjct: 68 KLREFPRGAANHDLTDTTR-ADLSRNRLSEIPIEACHFVSLENLNLYQNCIRYIPEAILN 126
Query: 554 LKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKI 375
L+ L LNIS N + TLPV L NL LK + ASNNKL + P++I L+ L LD+S N+I
Sbjct: 127 LQALTFLNISRNQLSTLPVHLCNL-PLKVLIASNNKLVSLPEEIGHLRHLMELDVSCNEI 185
Query: 374 TEIPYGMSELYVI-ELNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSK 198
IP + L + +LN+ +N + + E+L + P ++RLD +C + I
Sbjct: 186 QTIPSQIGNLEALRDLNVRRNHLVHLPEELAELP---LIRLDFSCNKITTIPVCYRNLRH 242
Query: 197 IHTVSVDGN 171
+ T+++D N
Sbjct: 243 LQTITLDNN 251
Score = 88.2 bits (209), Expect = 3e-17
Identities = 56/163 (34%), Positives = 91/163 (55%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
+L EIPI+ L NL+L +N + +P+ + L+ L LN+ N+L LP L NL
Sbjct: 93 RLSEIPIEACHFVS-LENLNLYQNCIRYIPEAILNLQALTFLNISRNQLSTLPVHLCNLP 151
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITE 369
L+VL SNN + +LP + +L +L ++ S N++Q P QI L++L L++ N +
Sbjct: 152 -LKVLIASNNKLVSLPEEIGHLRHLMELDVSCNEIQTIPSQIGNLEALRDLNVRRNHLVH 210
Query: 368 IPYGMSELYVIELNLSQNEISLIGEDLHQAPRLKILRLDENCL 240
+P ++EL +I L+ S N+I+ I L+ + LD N L
Sbjct: 211 LPEELAELPLIRLDFSCNKITTIPVCYRNLRHLQTITLDNNPL 253
Score = 67.3 bits (157), Expect = 5e-11
Identities = 37/102 (36%), Positives = 59/102 (57%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
KL +P ++ L ++ LD+S N++ +P + L+ L+ LN+ N L LPE L L
Sbjct: 161 KLVSLPEEIGHLRHLME-LDVSCNEIQTIPSQIGNLEALRDLNVRRNHLVHLPEELAELP 219
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQI 423
+ L+ S N + T+PVC +NL +L+ + NN LQ+ P QI
Sbjct: 220 LIR-LDFSCNKITTIPVCYRNLRHLQTITLDNNPLQSPPAQI 260
Score = 37.1 bits (82), Expect = 0.066
Identities = 18/54 (33%), Positives = 29/54 (53%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISN 522
L LD S NK++ +P L+HL+ + LD+N LQ+ P + K+ + N
Sbjct: 220 LIRLDFSCNKITTIPVCYRNLRHLQTITLDNNPLQSPPAQICIKGKVHIFKYLN 273
>AB020669-1|BAA74885.2| 584|Homo sapiens KIAA0862 protein protein.
Length = 584
Score = 103 bits (248), Expect = 5e-22
Identities = 60/185 (32%), Positives = 106/185 (57%), Gaps = 1/185 (0%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
++ +IP +FS VL L++ N+L+ LP D + +LNL +N+L +PE + L
Sbjct: 368 RINKIPFGIFSRAKVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPEDVSGLV 427
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITE 369
LEVL +SNN ++ LP L NL L+++ NKL++ P +I L+ L L L++N++T
Sbjct: 428 SLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLTNNQLTT 487
Query: 368 IPYGMSEL-YVIELNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIH 192
+P G+ L + L L +N ++ + E++ L+ L L++N +L + L SK+
Sbjct: 488 LPRGIGHLTNLTHLGLGENLLTHLPEEIGTLENLEELYLNDN-PNLHSLPLELALCSKLS 546
Query: 191 TVSVD 177
+S++
Sbjct: 547 IMSIE 551
Score = 83.0 bits (196), Expect = 1e-15
Identities = 47/147 (31%), Positives = 82/147 (55%), Gaps = 1/147 (0%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTL 504
L L L NKL LP ++ L +L L L N L +LP+SL NLKKL +L++ +N ++ +
Sbjct: 127 LTELYLYSNKLQSLPAEVGCLVNLMTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREI 186
Query: 503 PVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSEL-YVIELN 327
P + L++L +Y N++ K I L L +L + NKI ++P + EL +I L+
Sbjct: 187 PSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIKQLPAEIGELCNLITLD 246
Query: 326 LSQNEISLIGEDLHQAPRLKILRLDEN 246
++ N++ + +++ ++ L L N
Sbjct: 247 VAHNQLEHLPKEIGNCTQITNLDLQHN 273
Score = 83.0 bits (196), Expect = 1e-15
Identities = 54/176 (30%), Positives = 94/176 (53%), Gaps = 2/176 (1%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTL 504
LR LDL NKL +P + +L L L L N++ + + + NL KL +L+I N ++ L
Sbjct: 173 LRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIKQL 232
Query: 503 PVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVI-ELN 327
P + L NL + ++N+L+ PK+I + LDL HN++ ++P + L + L
Sbjct: 233 PAEIGELCNLITLDVAHNQLEHLPKEIGNCTQITNLDLQHNELLDLPDTIGNLSSLSRLG 292
Query: 326 LSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRD-SKIHTVSVDGNLFE 162
L N +S I L + L+ L L+ N ++ + SLL K++++++ N F+
Sbjct: 293 LRYNRLSAIPRSLAKCSALEELNLENN--NISTLPESLLSSLVKLNSLTLARNCFQ 346
Score = 82.6 bits (195), Expect = 1e-15
Identities = 55/172 (31%), Positives = 91/172 (52%), Gaps = 4/172 (2%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESL 561
+A +L+ +P ++ + C + NLDL N+L LPD + L L +L L N+L A+P SL
Sbjct: 247 VAHNQLEHLPKEIGN-CTQITNLDLQHNELLDLPDTIGNLSSLSRLGLRYNRLSAIPRSL 305
Query: 560 INLKKLEVLNISNNFVQTLP-VCLKNLNNLKQVYASNNKLQAFP-KQILGLQSLDVLDLS 387
LE LN+ NN + TLP L +L L + + N Q +P ++ L++
Sbjct: 306 AKCSALEELNLENNNISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNME 365
Query: 386 HNKITEIPYGM-SELYVI-ELNLSQNEISLIGEDLHQAPRLKILRLDENCLS 237
HN+I +IP+G+ S V+ +LN+ N+++ + D + L L N L+
Sbjct: 366 HNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLT 417
Score = 79.0 bits (186), Expect = 2e-14
Identities = 49/146 (33%), Positives = 77/146 (52%), Gaps = 1/146 (0%)
Frame = -2
Query: 674 LDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTLPVC 495
LDLSK + +LP + +L L +L L SNKLQ+LP + L L L +S N + +LP
Sbjct: 107 LDLSKRSIHILPSSIKELTQLTELYLYSNKLQSLPAEVGCLVNLMTLALSENSLTSLPDS 166
Query: 494 LKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVIE-LNLSQ 318
L NL L+ + +NKL+ P + L SL L L N+IT + + L + L++ +
Sbjct: 167 LDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRE 226
Query: 317 NEISLIGEDLHQAPRLKILRLDENCL 240
N+I + ++ + L L + N L
Sbjct: 227 NKIKQLPAEIGELCNLITLDVAHNQL 252
Score = 73.3 bits (172), Expect = 8e-13
Identities = 47/172 (27%), Positives = 88/172 (51%), Gaps = 4/172 (2%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESL 561
I + K+K++P ++ LC+++ LD++ N+L LP ++ + L+L N+L LP+++
Sbjct: 224 IRENKIKQLPAEIGELCNLI-TLDVAHNQLEHLPKEIGNCTQITNLDLQHNELLDLPDTI 282
Query: 560 INLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQIL-GLQSLDVLDLSH 384
NL L L + N + +P L + L+++ NN + P+ +L L L+ L L+
Sbjct: 283 GNLSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLPESLLSSLVKLNSLTLAR 342
Query: 383 NKITEIPYGMSELY--VIELNLSQNEISLIGEDL-HQAPRLKILRLDENCLS 237
N P G + + LN+ N I+ I + +A L L + +N L+
Sbjct: 343 NCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLT 394
Score = 66.5 bits (155), Expect = 9e-11
Identities = 43/133 (32%), Positives = 71/133 (53%), Gaps = 3/133 (2%)
Frame = -2
Query: 635 DLSKLKHLKQLNLDSNK--LQALPESLINLKKLEVLNISNNFVQTLPVCLKNLNNLKQVY 462
+L+K + + LD +K + LP S+ L +L L + +N +Q+LP + L NL +
Sbjct: 95 ELNKCREENSMRLDLSKRSIHILPSSIKELTQLTELYLYSNKLQSLPAEVGCLVNLMTLA 154
Query: 461 ASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSEL-YVIELNLSQNEISLIGEDLH 285
S N L + P + L+ L +LDL HNK+ EIP + L + L L N I+ + +D+
Sbjct: 155 LSENSLTSLPDSLDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDIK 214
Query: 284 QAPRLKILRLDEN 246
+L +L + EN
Sbjct: 215 NLSKLSMLSIREN 227
>BC050445-1|AAH50445.1| 582|Homo sapiens soc-2 suppressor of clear
homolog (C. elegans) protein.
Length = 582
Score = 103 bits (247), Expect = 7e-22
Identities = 60/185 (32%), Positives = 106/185 (57%), Gaps = 1/185 (0%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
++ +IP +FS VL L++ N+L+ LP D + +LNL +N+L +PE + L
Sbjct: 366 RINKIPFGIFSRAKVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPEDVSGLV 425
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITE 369
LEVL +SNN ++ LP L NL L+++ NKL++ P +I L+ L L L++N++T
Sbjct: 426 SLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLTNNQLTT 485
Query: 368 IPYGMSEL-YVIELNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIH 192
+P G+ L + L L +N ++ + E++ L+ L L++N +L + L SK+
Sbjct: 486 LPRGIGHLTNLTHLGLGENLLTHLPEEIGTLENLEELYLNDN-PNLHSLPFELALCSKLS 544
Query: 191 TVSVD 177
+S++
Sbjct: 545 IMSIE 549
Score = 83.0 bits (196), Expect = 1e-15
Identities = 47/147 (31%), Positives = 82/147 (55%), Gaps = 1/147 (0%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTL 504
L L L NKL LP ++ L +L L L N L +LP+SL NLKKL +L++ +N ++ +
Sbjct: 125 LTELYLYSNKLQSLPAEVGCLVNLMTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREI 184
Query: 503 PVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSEL-YVIELN 327
P + L++L +Y N++ K I L L +L + NKI ++P + EL +I L+
Sbjct: 185 PSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIKQLPAEIGELCNLITLD 244
Query: 326 LSQNEISLIGEDLHQAPRLKILRLDEN 246
++ N++ + +++ ++ L L N
Sbjct: 245 VAHNQLEHLPKEIGNCTQITNLDLQHN 271
Score = 83.0 bits (196), Expect = 1e-15
Identities = 54/176 (30%), Positives = 94/176 (53%), Gaps = 2/176 (1%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTL 504
LR LDL NKL +P + +L L L L N++ + + + NL KL +L+I N ++ L
Sbjct: 171 LRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIKQL 230
Query: 503 PVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVI-ELN 327
P + L NL + ++N+L+ PK+I + LDL HN++ ++P + L + L
Sbjct: 231 PAEIGELCNLITLDVAHNQLEHLPKEIGNCTQITNLDLQHNELLDLPDTIGNLSSLSRLG 290
Query: 326 LSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRD-SKIHTVSVDGNLFE 162
L N +S I L + L+ L L+ N ++ + SLL K++++++ N F+
Sbjct: 291 LRYNRLSAIPRSLAKCSALEELNLENN--NISTLPESLLSSLVKLNSLTLARNCFQ 344
Score = 82.6 bits (195), Expect = 1e-15
Identities = 55/172 (31%), Positives = 91/172 (52%), Gaps = 4/172 (2%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESL 561
+A +L+ +P ++ + C + NLDL N+L LPD + L L +L L N+L A+P SL
Sbjct: 245 VAHNQLEHLPKEIGN-CTQITNLDLQHNELLDLPDTIGNLSSLSRLGLRYNRLSAIPRSL 303
Query: 560 INLKKLEVLNISNNFVQTLP-VCLKNLNNLKQVYASNNKLQAFP-KQILGLQSLDVLDLS 387
LE LN+ NN + TLP L +L L + + N Q +P ++ L++
Sbjct: 304 AKCSALEELNLENNNISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNME 363
Query: 386 HNKITEIPYGM-SELYVI-ELNLSQNEISLIGEDLHQAPRLKILRLDENCLS 237
HN+I +IP+G+ S V+ +LN+ N+++ + D + L L N L+
Sbjct: 364 HNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLT 415
Score = 79.0 bits (186), Expect = 2e-14
Identities = 49/146 (33%), Positives = 77/146 (52%), Gaps = 1/146 (0%)
Frame = -2
Query: 674 LDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTLPVC 495
LDLSK + +LP + +L L +L L SNKLQ+LP + L L L +S N + +LP
Sbjct: 105 LDLSKRSIHILPSSIKELTQLTELYLYSNKLQSLPAEVGCLVNLMTLALSENSLTSLPDS 164
Query: 494 LKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVIE-LNLSQ 318
L NL L+ + +NKL+ P + L SL L L N+IT + + L + L++ +
Sbjct: 165 LDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRE 224
Query: 317 NEISLIGEDLHQAPRLKILRLDENCL 240
N+I + ++ + L L + N L
Sbjct: 225 NKIKQLPAEIGELCNLITLDVAHNQL 250
Score = 73.3 bits (172), Expect = 8e-13
Identities = 47/172 (27%), Positives = 88/172 (51%), Gaps = 4/172 (2%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESL 561
I + K+K++P ++ LC+++ LD++ N+L LP ++ + L+L N+L LP+++
Sbjct: 222 IRENKIKQLPAEIGELCNLI-TLDVAHNQLEHLPKEIGNCTQITNLDLQHNELLDLPDTI 280
Query: 560 INLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQIL-GLQSLDVLDLSH 384
NL L L + N + +P L + L+++ NN + P+ +L L L+ L L+
Sbjct: 281 GNLSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLPESLLSSLVKLNSLTLAR 340
Query: 383 NKITEIPYGMSELY--VIELNLSQNEISLIGEDL-HQAPRLKILRLDENCLS 237
N P G + + LN+ N I+ I + +A L L + +N L+
Sbjct: 341 NCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLT 392
Score = 66.5 bits (155), Expect = 9e-11
Identities = 43/133 (32%), Positives = 71/133 (53%), Gaps = 3/133 (2%)
Frame = -2
Query: 635 DLSKLKHLKQLNLDSNK--LQALPESLINLKKLEVLNISNNFVQTLPVCLKNLNNLKQVY 462
+L+K + + LD +K + LP S+ L +L L + +N +Q+LP + L NL +
Sbjct: 93 ELNKCREENSMRLDLSKRSIHILPSSIKELTQLTELYLYSNKLQSLPAEVGCLVNLMTLA 152
Query: 461 ASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSEL-YVIELNLSQNEISLIGEDLH 285
S N L + P + L+ L +LDL HNK+ EIP + L + L L N I+ + +D+
Sbjct: 153 LSENSLTSLPDSLDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDIK 212
Query: 284 QAPRLKILRLDEN 246
+L +L + EN
Sbjct: 213 NLSKLSMLSIREN 225
>AL158163-3|CAH72813.1| 372|Homo sapiens soc-2 suppressor of clear
homolog (C. elegans) protein.
Length = 372
Score = 103 bits (247), Expect = 7e-22
Identities = 60/185 (32%), Positives = 106/185 (57%), Gaps = 1/185 (0%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
++ +IP +FS VL L++ N+L+ LP D + +LNL +N+L +PE + L
Sbjct: 156 RINKIPFGIFSRAKVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPEDVSGLV 215
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITE 369
LEVL +SNN ++ LP L NL L+++ NKL++ P +I L+ L L L++N++T
Sbjct: 216 SLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLTNNQLTT 275
Query: 368 IPYGMSEL-YVIELNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIH 192
+P G+ L + L L +N ++ + E++ L+ L L++N +L + L SK+
Sbjct: 276 LPRGIGHLTNLTHLGLGENLLTHLPEEIGTLENLEELYLNDN-PNLHSLPFELALCSKLS 334
Query: 191 TVSVD 177
+S++
Sbjct: 335 IMSIE 339
Score = 76.6 bits (180), Expect = 9e-14
Identities = 51/157 (32%), Positives = 83/157 (52%), Gaps = 3/157 (1%)
Frame = -2
Query: 632 LSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASN 453
L LK L+ L+L NKL+ +P + L L L + N + T+ +KNL+ L +
Sbjct: 1 LDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRE 60
Query: 452 NKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVI-ELNLSQNEISLIGED-LHQA 279
NK++ P +I L SL L L +N+++ IP +++ + ELNL N IS + E L
Sbjct: 61 NKIKQLPAEIGNLSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLPESLLSSL 120
Query: 278 PRLKILRLDENCLSLDEI-KPSLLRDSKIHTVSVDGN 171
+L L L NC L + PS + S I++++++ N
Sbjct: 121 VKLNSLTLARNCFQLYPVGGPS--QFSTIYSLNMEHN 155
Score = 72.1 bits (169), Expect = 2e-12
Identities = 48/153 (31%), Positives = 79/153 (51%), Gaps = 4/153 (2%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTL 504
L L + +NK+ LP ++ L L +L L N+L A+P SL LE LN+ NN + TL
Sbjct: 53 LSMLSIRENKIKQLPAEIGNLSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTL 112
Query: 503 PVCL-KNLNNLKQVYASNNKLQAFPKQILG-LQSLDVLDLSHNKITEIPYGM-SELYVI- 336
P L +L L + + N Q +P ++ L++ HN+I +IP+G+ S V+
Sbjct: 113 PESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLS 172
Query: 335 ELNLSQNEISLIGEDLHQAPRLKILRLDENCLS 237
+LN+ N+++ + D + L L N L+
Sbjct: 173 KLNMKDNQLTSLPLDFGTWTSMVELNLATNQLT 205
Score = 69.7 bits (163), Expect = 1e-11
Identities = 40/125 (32%), Positives = 71/125 (56%), Gaps = 2/125 (1%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTL 504
LR LDL NKL +P + +L L L L N++ + + + NL KL +L+I N ++ L
Sbjct: 7 LRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIKQL 66
Query: 503 PVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGM--SELYVIEL 330
P + NL++L ++ N+L A P+ + +L+ L+L +N I+ +P + S + + L
Sbjct: 67 PAEIGNLSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLPESLLSSLVKLNSL 126
Query: 329 NLSQN 315
L++N
Sbjct: 127 TLARN 131
>AL158163-2|CAH72812.1| 582|Homo sapiens soc-2 suppressor of clear
homolog (C. elegans) protein.
Length = 582
Score = 103 bits (247), Expect = 7e-22
Identities = 60/185 (32%), Positives = 106/185 (57%), Gaps = 1/185 (0%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
++ +IP +FS VL L++ N+L+ LP D + +LNL +N+L +PE + L
Sbjct: 366 RINKIPFGIFSRAKVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPEDVSGLV 425
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITE 369
LEVL +SNN ++ LP L NL L+++ NKL++ P +I L+ L L L++N++T
Sbjct: 426 SLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLTNNQLTT 485
Query: 368 IPYGMSEL-YVIELNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIH 192
+P G+ L + L L +N ++ + E++ L+ L L++N +L + L SK+
Sbjct: 486 LPRGIGHLTNLTHLGLGENLLTHLPEEIGTLENLEELYLNDN-PNLHSLPFELALCSKLS 544
Query: 191 TVSVD 177
+S++
Sbjct: 545 IMSIE 549
Score = 83.0 bits (196), Expect = 1e-15
Identities = 47/147 (31%), Positives = 82/147 (55%), Gaps = 1/147 (0%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTL 504
L L L NKL LP ++ L +L L L N L +LP+SL NLKKL +L++ +N ++ +
Sbjct: 125 LTELYLYSNKLQSLPAEVGCLVNLMTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREI 184
Query: 503 PVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSEL-YVIELN 327
P + L++L +Y N++ K I L L +L + NKI ++P + EL +I L+
Sbjct: 185 PSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIKQLPAEIGELCNLITLD 244
Query: 326 LSQNEISLIGEDLHQAPRLKILRLDEN 246
++ N++ + +++ ++ L L N
Sbjct: 245 VAHNQLEHLPKEIGNCTQITNLDLQHN 271
Score = 83.0 bits (196), Expect = 1e-15
Identities = 54/176 (30%), Positives = 94/176 (53%), Gaps = 2/176 (1%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTL 504
LR LDL NKL +P + +L L L L N++ + + + NL KL +L+I N ++ L
Sbjct: 171 LRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIKQL 230
Query: 503 PVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVI-ELN 327
P + L NL + ++N+L+ PK+I + LDL HN++ ++P + L + L
Sbjct: 231 PAEIGELCNLITLDVAHNQLEHLPKEIGNCTQITNLDLQHNELLDLPDTIGNLSSLSRLG 290
Query: 326 LSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRD-SKIHTVSVDGNLFE 162
L N +S I L + L+ L L+ N ++ + SLL K++++++ N F+
Sbjct: 291 LRYNRLSAIPRSLAKCSALEELNLENN--NISTLPESLLSSLVKLNSLTLARNCFQ 344
Score = 82.6 bits (195), Expect = 1e-15
Identities = 55/172 (31%), Positives = 91/172 (52%), Gaps = 4/172 (2%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESL 561
+A +L+ +P ++ + C + NLDL N+L LPD + L L +L L N+L A+P SL
Sbjct: 245 VAHNQLEHLPKEIGN-CTQITNLDLQHNELLDLPDTIGNLSSLSRLGLRYNRLSAIPRSL 303
Query: 560 INLKKLEVLNISNNFVQTLP-VCLKNLNNLKQVYASNNKLQAFP-KQILGLQSLDVLDLS 387
LE LN+ NN + TLP L +L L + + N Q +P ++ L++
Sbjct: 304 AKCSALEELNLENNNISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNME 363
Query: 386 HNKITEIPYGM-SELYVI-ELNLSQNEISLIGEDLHQAPRLKILRLDENCLS 237
HN+I +IP+G+ S V+ +LN+ N+++ + D + L L N L+
Sbjct: 364 HNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLT 415
Score = 79.0 bits (186), Expect = 2e-14
Identities = 49/146 (33%), Positives = 77/146 (52%), Gaps = 1/146 (0%)
Frame = -2
Query: 674 LDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTLPVC 495
LDLSK + +LP + +L L +L L SNKLQ+LP + L L L +S N + +LP
Sbjct: 105 LDLSKRSIHILPSSIKELTQLTELYLYSNKLQSLPAEVGCLVNLMTLALSENSLTSLPDS 164
Query: 494 LKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVIE-LNLSQ 318
L NL L+ + +NKL+ P + L SL L L N+IT + + L + L++ +
Sbjct: 165 LDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRE 224
Query: 317 NEISLIGEDLHQAPRLKILRLDENCL 240
N+I + ++ + L L + N L
Sbjct: 225 NKIKQLPAEIGELCNLITLDVAHNQL 250
Score = 73.3 bits (172), Expect = 8e-13
Identities = 47/172 (27%), Positives = 88/172 (51%), Gaps = 4/172 (2%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESL 561
I + K+K++P ++ LC+++ LD++ N+L LP ++ + L+L N+L LP+++
Sbjct: 222 IRENKIKQLPAEIGELCNLI-TLDVAHNQLEHLPKEIGNCTQITNLDLQHNELLDLPDTI 280
Query: 560 INLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQIL-GLQSLDVLDLSH 384
NL L L + N + +P L + L+++ NN + P+ +L L L+ L L+
Sbjct: 281 GNLSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLPESLLSSLVKLNSLTLAR 340
Query: 383 NKITEIPYGMSELY--VIELNLSQNEISLIGEDL-HQAPRLKILRLDENCLS 237
N P G + + LN+ N I+ I + +A L L + +N L+
Sbjct: 341 NCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLT 392
Score = 66.5 bits (155), Expect = 9e-11
Identities = 43/133 (32%), Positives = 71/133 (53%), Gaps = 3/133 (2%)
Frame = -2
Query: 635 DLSKLKHLKQLNLDSNK--LQALPESLINLKKLEVLNISNNFVQTLPVCLKNLNNLKQVY 462
+L+K + + LD +K + LP S+ L +L L + +N +Q+LP + L NL +
Sbjct: 93 ELNKCREENSMRLDLSKRSIHILPSSIKELTQLTELYLYSNKLQSLPAEVGCLVNLMTLA 152
Query: 461 ASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSEL-YVIELNLSQNEISLIGEDLH 285
S N L + P + L+ L +LDL HNK+ EIP + L + L L N I+ + +D+
Sbjct: 153 LSENSLTSLPDSLDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDIK 212
Query: 284 QAPRLKILRLDEN 246
+L +L + EN
Sbjct: 213 NLSKLSMLSIREN 225
>AF068920-1|AAC39856.1| 582|Homo sapiens Ras-binding protein SUR-8
protein.
Length = 582
Score = 103 bits (247), Expect = 7e-22
Identities = 60/185 (32%), Positives = 106/185 (57%), Gaps = 1/185 (0%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
++ +IP +FS VL L++ N+L+ LP D + +LNL +N+L +PE + L
Sbjct: 366 RINKIPFGIFSRAKVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPEDVSGLV 425
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITE 369
LEVL +SNN ++ LP L NL L+++ NKL++ P +I L+ L L L++N++T
Sbjct: 426 SLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLTNNQLTT 485
Query: 368 IPYGMSEL-YVIELNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIH 192
+P G+ L + L L +N ++ + E++ L+ L L++N +L + L SK+
Sbjct: 486 LPRGIGHLTNLTHLGLGENLLTHLPEEIGTLENLEELYLNDN-PNLHSLPFELALCSKLS 544
Query: 191 TVSVD 177
+S++
Sbjct: 545 IMSIE 549
Score = 83.0 bits (196), Expect = 1e-15
Identities = 47/147 (31%), Positives = 82/147 (55%), Gaps = 1/147 (0%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTL 504
L L L NKL LP ++ L +L L L N L +LP+SL NLKKL +L++ +N ++ +
Sbjct: 125 LTELYLYSNKLQSLPAEVGCLVNLMTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREI 184
Query: 503 PVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSEL-YVIELN 327
P + L++L +Y N++ K I L L +L + NKI ++P + EL +I L+
Sbjct: 185 PSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIKQLPAEIGELCNLITLD 244
Query: 326 LSQNEISLIGEDLHQAPRLKILRLDEN 246
++ N++ + +++ ++ L L N
Sbjct: 245 VAHNQLEHLPKEIGNCTQITNLDLQHN 271
Score = 83.0 bits (196), Expect = 1e-15
Identities = 54/176 (30%), Positives = 94/176 (53%), Gaps = 2/176 (1%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTL 504
LR LDL NKL +P + +L L L L N++ + + + NL KL +L+I N ++ L
Sbjct: 171 LRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIKQL 230
Query: 503 PVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVI-ELN 327
P + L NL + ++N+L+ PK+I + LDL HN++ ++P + L + L
Sbjct: 231 PAEIGELCNLITLDVAHNQLEHLPKEIGNCTQITNLDLQHNELLDLPDTIGNLSSLSRLG 290
Query: 326 LSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRD-SKIHTVSVDGNLFE 162
L N +S I L + L+ L L+ N ++ + SLL K++++++ N F+
Sbjct: 291 LRYNRLSAIPRSLAKCSALEELNLENN--NISTLPESLLSSLVKLNSLTLARNCFQ 344
Score = 82.6 bits (195), Expect = 1e-15
Identities = 55/172 (31%), Positives = 91/172 (52%), Gaps = 4/172 (2%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESL 561
+A +L+ +P ++ + C + NLDL N+L LPD + L L +L L N+L A+P SL
Sbjct: 245 VAHNQLEHLPKEIGN-CTQITNLDLQHNELLDLPDTIGNLSSLSRLGLRYNRLSAIPRSL 303
Query: 560 INLKKLEVLNISNNFVQTLP-VCLKNLNNLKQVYASNNKLQAFP-KQILGLQSLDVLDLS 387
LE LN+ NN + TLP L +L L + + N Q +P ++ L++
Sbjct: 304 AKCSALEELNLENNNISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNME 363
Query: 386 HNKITEIPYGM-SELYVI-ELNLSQNEISLIGEDLHQAPRLKILRLDENCLS 237
HN+I +IP+G+ S V+ +LN+ N+++ + D + L L N L+
Sbjct: 364 HNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLT 415
Score = 79.0 bits (186), Expect = 2e-14
Identities = 49/146 (33%), Positives = 77/146 (52%), Gaps = 1/146 (0%)
Frame = -2
Query: 674 LDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTLPVC 495
LDLSK + +LP + +L L +L L SNKLQ+LP + L L L +S N + +LP
Sbjct: 105 LDLSKRSIHILPSSIKELTQLTELYLYSNKLQSLPAEVGCLVNLMTLALSENSLTSLPDS 164
Query: 494 LKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVIE-LNLSQ 318
L NL L+ + +NKL+ P + L SL L L N+IT + + L + L++ +
Sbjct: 165 LDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRE 224
Query: 317 NEISLIGEDLHQAPRLKILRLDENCL 240
N+I + ++ + L L + N L
Sbjct: 225 NKIKQLPAEIGELCNLITLDVAHNQL 250
Score = 73.3 bits (172), Expect = 8e-13
Identities = 47/172 (27%), Positives = 88/172 (51%), Gaps = 4/172 (2%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESL 561
I + K+K++P ++ LC+++ LD++ N+L LP ++ + L+L N+L LP+++
Sbjct: 222 IRENKIKQLPAEIGELCNLI-TLDVAHNQLEHLPKEIGNCTQITNLDLQHNELLDLPDTI 280
Query: 560 INLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQIL-GLQSLDVLDLSH 384
NL L L + N + +P L + L+++ NN + P+ +L L L+ L L+
Sbjct: 281 GNLSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLPESLLSSLVKLNSLTLAR 340
Query: 383 NKITEIPYGMSELY--VIELNLSQNEISLIGEDL-HQAPRLKILRLDENCLS 237
N P G + + LN+ N I+ I + +A L L + +N L+
Sbjct: 341 NCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLT 392
Score = 66.5 bits (155), Expect = 9e-11
Identities = 43/133 (32%), Positives = 71/133 (53%), Gaps = 3/133 (2%)
Frame = -2
Query: 635 DLSKLKHLKQLNLDSNK--LQALPESLINLKKLEVLNISNNFVQTLPVCLKNLNNLKQVY 462
+L+K + + LD +K + LP S+ L +L L + +N +Q+LP + L NL +
Sbjct: 93 ELNKCREENSMRLDLSKRSIHILPSSIKELTQLTELYLYSNKLQSLPAEVGCLVNLMTLA 152
Query: 461 ASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSEL-YVIELNLSQNEISLIGEDLH 285
S N L + P + L+ L +LDL HNK+ EIP + L + L L N I+ + +D+
Sbjct: 153 LSENSLTSLPDSLDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDIK 212
Query: 284 QAPRLKILRLDEN 246
+L +L + EN
Sbjct: 213 NLSKLSMLSIREN 225
>AF054828-1|AAC25698.1| 582|Homo sapiens leucine-rich repeat
protein SHOC-2 protein.
Length = 582
Score = 103 bits (247), Expect = 7e-22
Identities = 60/185 (32%), Positives = 106/185 (57%), Gaps = 1/185 (0%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
++ +IP +FS VL L++ N+L+ LP D + +LNL +N+L +PE + L
Sbjct: 366 RINKIPFGIFSRAKVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPEDVSGLV 425
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITE 369
LEVL +SNN ++ LP L NL L+++ NKL++ P +I L+ L L L++N++T
Sbjct: 426 SLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLTNNQLTT 485
Query: 368 IPYGMSEL-YVIELNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIH 192
+P G+ L + L L +N ++ + E++ L+ L L++N +L + L SK+
Sbjct: 486 LPRGIGHLTNLTHLGLGENLLTHLPEEIGTLENLEELYLNDN-PNLHSLPFELALCSKLS 544
Query: 191 TVSVD 177
+S++
Sbjct: 545 IMSIE 549
Score = 83.0 bits (196), Expect = 1e-15
Identities = 47/147 (31%), Positives = 82/147 (55%), Gaps = 1/147 (0%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTL 504
L L L NKL LP ++ L +L L L N L +LP+SL NLKKL +L++ +N ++ +
Sbjct: 125 LTELYLYSNKLQSLPAEVGCLVNLMTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREI 184
Query: 503 PVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSEL-YVIELN 327
P + L++L +Y N++ K I L L +L + NKI ++P + EL +I L+
Sbjct: 185 PSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIKQLPAEIGELCNLITLD 244
Query: 326 LSQNEISLIGEDLHQAPRLKILRLDEN 246
++ N++ + +++ ++ L L N
Sbjct: 245 VAHNQLEHLPKEIGNCTQITNLDLQHN 271
Score = 83.0 bits (196), Expect = 1e-15
Identities = 54/176 (30%), Positives = 94/176 (53%), Gaps = 2/176 (1%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTL 504
LR LDL NKL +P + +L L L L N++ + + + NL KL +L+I N ++ L
Sbjct: 171 LRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIKQL 230
Query: 503 PVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVI-ELN 327
P + L NL + ++N+L+ PK+I + LDL HN++ ++P + L + L
Sbjct: 231 PAEIGELCNLITLDVAHNQLEHLPKEIGNCTQITNLDLQHNELLDLPDTIGNLSSLSRLG 290
Query: 326 LSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRD-SKIHTVSVDGNLFE 162
L N +S I L + L+ L L+ N ++ + SLL K++++++ N F+
Sbjct: 291 LRYNRLSAIPRSLAKCSALEELNLENN--NISTLPESLLSSLVKLNSLTLARNCFQ 344
Score = 82.6 bits (195), Expect = 1e-15
Identities = 55/172 (31%), Positives = 91/172 (52%), Gaps = 4/172 (2%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESL 561
+A +L+ +P ++ + C + NLDL N+L LPD + L L +L L N+L A+P SL
Sbjct: 245 VAHNQLEHLPKEIGN-CTQITNLDLQHNELLDLPDTIGNLSSLSRLGLRYNRLSAIPRSL 303
Query: 560 INLKKLEVLNISNNFVQTLP-VCLKNLNNLKQVYASNNKLQAFP-KQILGLQSLDVLDLS 387
LE LN+ NN + TLP L +L L + + N Q +P ++ L++
Sbjct: 304 AKCSALEELNLENNNISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNME 363
Query: 386 HNKITEIPYGM-SELYVI-ELNLSQNEISLIGEDLHQAPRLKILRLDENCLS 237
HN+I +IP+G+ S V+ +LN+ N+++ + D + L L N L+
Sbjct: 364 HNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLT 415
Score = 79.0 bits (186), Expect = 2e-14
Identities = 49/146 (33%), Positives = 77/146 (52%), Gaps = 1/146 (0%)
Frame = -2
Query: 674 LDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTLPVC 495
LDLSK + +LP + +L L +L L SNKLQ+LP + L L L +S N + +LP
Sbjct: 105 LDLSKRSIHILPSSIKELTQLTELYLYSNKLQSLPAEVGCLVNLMTLALSENSLTSLPDS 164
Query: 494 LKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVIE-LNLSQ 318
L NL L+ + +NKL+ P + L SL L L N+IT + + L + L++ +
Sbjct: 165 LDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRE 224
Query: 317 NEISLIGEDLHQAPRLKILRLDENCL 240
N+I + ++ + L L + N L
Sbjct: 225 NKIKQLPAEIGELCNLITLDVAHNQL 250
Score = 73.3 bits (172), Expect = 8e-13
Identities = 47/172 (27%), Positives = 88/172 (51%), Gaps = 4/172 (2%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESL 561
I + K+K++P ++ LC+++ LD++ N+L LP ++ + L+L N+L LP+++
Sbjct: 222 IRENKIKQLPAEIGELCNLI-TLDVAHNQLEHLPKEIGNCTQITNLDLQHNELLDLPDTI 280
Query: 560 INLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQIL-GLQSLDVLDLSH 384
NL L L + N + +P L + L+++ NN + P+ +L L L+ L L+
Sbjct: 281 GNLSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLPESLLSSLVKLNSLTLAR 340
Query: 383 NKITEIPYGMSELY--VIELNLSQNEISLIGEDL-HQAPRLKILRLDENCLS 237
N P G + + LN+ N I+ I + +A L L + +N L+
Sbjct: 341 NCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLT 392
Score = 66.5 bits (155), Expect = 9e-11
Identities = 43/133 (32%), Positives = 71/133 (53%), Gaps = 3/133 (2%)
Frame = -2
Query: 635 DLSKLKHLKQLNLDSNK--LQALPESLINLKKLEVLNISNNFVQTLPVCLKNLNNLKQVY 462
+L+K + + LD +K + LP S+ L +L L + +N +Q+LP + L NL +
Sbjct: 93 ELNKCREENSMRLDLSKRSIHILPSSIKELTQLTELYLYSNKLQSLPAEVGCLVNLMTLA 152
Query: 461 ASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSEL-YVIELNLSQNEISLIGEDLH 285
S N L + P + L+ L +LDL HNK+ EIP + L + L L N I+ + +D+
Sbjct: 153 LSENSLTSLPDSLDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDIK 212
Query: 284 QAPRLKILRLDEN 246
+L +L + EN
Sbjct: 213 NLSKLSMLSIREN 225
>BC125224-1|AAI25225.1| 748|Homo sapiens LRCH2 protein protein.
Length = 748
Score = 103 bits (246), Expect = 9e-22
Identities = 63/187 (33%), Positives = 108/187 (57%), Gaps = 1/187 (0%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
KL++ P + L D + DLS+N+ + +P D+ L+ LNL N ++ +PE++ NL+
Sbjct: 99 KLRDFPGSGYDLTDTTQ-ADLSRNRFTEIPSDVWLFAPLETLNLYHNCIKTIPEAIKNLQ 157
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITE 369
L LNIS N + TLP L +L LK + SNNKL + P++I L+ L LD+S N+I
Sbjct: 158 MLTYLNISRNLLSTLPKYLFDL-PLKVLVVSNNKLVSIPEEIGKLKDLMELDISCNEIQV 216
Query: 368 IPYGMSELYVI-ELNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIH 192
+P M +L+ + ELN+ +N + ++ ++L P +++LD +C + EI + +
Sbjct: 217 LPQQMGKLHSLRELNIRRNNLHVLPDELGDLP---LVKLDFSCNKVTEIPVCYRKLHHLQ 273
Query: 191 TVSVDGN 171
+ +D N
Sbjct: 274 VIILDNN 280
Score = 82.2 bits (194), Expect = 2e-15
Identities = 51/165 (30%), Positives = 93/165 (56%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
+ EIP DV+ L L L+L N + +P+ + L+ L LN+ N L LP+ L +L
Sbjct: 122 RFTEIPSDVW-LFAPLETLNLYHNCIKTIPEAIKNLQMLTYLNISRNLLSTLPKYLFDLP 180
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITE 369
L+VL +SNN + ++P + L +L ++ S N++Q P+Q+ L SL L++ N +
Sbjct: 181 -LKVLVVSNNKLVSIPEEIGKLKDLMELDISCNEIQVLPQQMGKLHSLRELNIRRNNLHV 239
Query: 368 IPYGMSELYVIELNLSQNEISLIGEDLHQAPRLKILRLDENCLSL 234
+P + +L +++L+ S N+++ I + L+++ LD N L +
Sbjct: 240 LPDELGDLPLVKLDFSCNKVTEIPVCYRKLHHLQVIILDNNPLQV 284
Score = 73.3 bits (172), Expect = 8e-13
Identities = 47/146 (32%), Positives = 75/146 (51%), Gaps = 1/146 (0%)
Frame = -2
Query: 674 LDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTLPVC 495
L LS KL P L Q +L N+ +P + LE LN+ +N ++T+P
Sbjct: 93 LSLSGRKLRDFPGSGYDLTDTTQADLSRNRFTEIPSDVWLFAPLETLNLYHNCIKTIPEA 152
Query: 494 LKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELY-VIELNLSQ 318
+KNL L + S N L PK + L L VL +S+NK+ IP + +L ++EL++S
Sbjct: 153 IKNLQMLTYLNISRNLLSTLPKYLFDL-PLKVLVVSNNKLVSIPEEIGKLKDLMELDISC 211
Query: 317 NEISLIGEDLHQAPRLKILRLDENCL 240
NEI ++ + + + L+ L + N L
Sbjct: 212 NEIQVLPQQMGKLHSLRELNIRRNNL 237
Score = 73.3 bits (172), Expect = 8e-13
Identities = 40/106 (37%), Positives = 65/106 (61%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESL 561
+++ KL IP ++ L D++ LD+S N++ VLP + KL L++LN+ N L LP+ L
Sbjct: 186 VSNNKLVSIPEEIGKLKDLME-LDISCNEIQVLPQQMGKLHSLRELNIRRNNLHVLPDEL 244
Query: 560 INLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQI 423
+L ++ L+ S N V +PVC + L++L+ + NN LQ P QI
Sbjct: 245 GDLPLVK-LDFSCNKVTEIPVCYRKLHHLQVIILDNNPLQVPPAQI 289
Score = 39.1 bits (87), Expect = 0.016
Identities = 35/116 (30%), Positives = 48/116 (41%), Gaps = 1/116 (0%)
Frame = -2
Query: 515 VQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVI 336
V++L L+ + + S KL+ FP L DLS N+ TEIP + +
Sbjct: 77 VRSLDRALEEAGSSGILSLSGRKLRDFPGSGYDLTDTTQADLSRNRFTEIPSDVWLFAPL 136
Query: 335 E-LNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIHTVSVDGN 171
E LNL N I I E + L L + N LS P L D + + V N
Sbjct: 137 ETLNLYHNCIKTIPEAIKNLQMLTYLNISRNLLS---TLPKYLFDLPLKVLVVSNN 189
Score = 34.7 bits (76), Expect = 0.35
Identities = 19/54 (35%), Positives = 28/54 (51%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISN 522
L LD S NK++ +P KL HL+ + LD+N LQ P + K+ + N
Sbjct: 249 LVKLDFSCNKVTEIPVCYRKLHHLQVIILDNNPLQVPPAQICLKGKVHIFKYLN 302
>BC008586-1|AAH08586.1| 602|Homo sapiens leucine rich repeat
containing 40 protein.
Length = 602
Score = 101 bits (242), Expect = 3e-21
Identities = 60/158 (37%), Positives = 92/158 (58%), Gaps = 1/158 (0%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTL 504
L L +S NKL L DDL L L L++ N+L +LP ++ L+ L+ LN+S+N ++ L
Sbjct: 84 LTKLIISNNKLQSLTDDLRLLPALTVLDIHDNQLTSLPSAIRELENLQKLNVSHNKLKIL 143
Query: 503 PVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSEL-YVIELN 327
P + NL NLK +Y +N+L + L +L+ LDLS+N +T +P S L ++ LN
Sbjct: 144 PEEITNLRNLKCLYLQHNELTCISEGFEQLSNLEDLDLSNNHLTTVPASFSSLSSLVRLN 203
Query: 326 LSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSL 213
LS NE+ + ++++ RLK LD N L+ I P L
Sbjct: 204 LSSNELKSLPAEINRMKRLK--HLDCNSNLLETIPPEL 239
Score = 87.0 bits (206), Expect = 6e-17
Identities = 54/172 (31%), Positives = 99/172 (57%), Gaps = 1/172 (0%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESL 561
I D +L +P + L + L+ L++S NKL +LP++++ L++LK L L N+L + E
Sbjct: 112 IHDNQLTSLPSAIREL-ENLQKLNVSHNKLKILPEEITNLRNLKCLYLQHNELTCISEGF 170
Query: 560 INLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHN 381
L LE L++SNN + T+P +L++L ++ S+N+L++ P +I ++ L LD + N
Sbjct: 171 EQLSNLEDLDLSNNHLTTVPASFSSLSSLVRLNLSSNELKSLPAEINRMKRLKHLDCNSN 230
Query: 380 KITEIPYGMSELYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDE 228
+ IP ++ + +E L L +N++ + E LK L + EN + + E
Sbjct: 231 LLETIPPELAGMESLELLYLRRNKLRFLPE-FPSCSLLKELHVGENQIEMLE 281
Score = 84.6 bits (200), Expect = 3e-16
Identities = 58/201 (28%), Positives = 104/201 (51%), Gaps = 1/201 (0%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESL 561
I++ KL+ + D+ L L LD+ N+L+ LP + +L++L++LN+ NKL+ LPE +
Sbjct: 89 ISNNKLQSLTDDL-RLLPALTVLDIHDNQLTSLPSAIRELENLQKLNVSHNKLKILPEEI 147
Query: 560 INLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHN 381
NL+ L+ L + +N + + + L+NL+ + SNN L P L SL L+LS N
Sbjct: 148 TNLRNLKCLYLQHNELTCISEGFEQLSNLEDLDLSNNHLTTVPASFSSLSSLVRLNLSSN 207
Query: 380 KITEIPYGMSELYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRD 204
++ +P ++ + ++ L+ + N + I +L L++L L N L PS
Sbjct: 208 ELKSLPAEINRMKRLKHLDCNSNLLETIPPELAGMESLELLYLRRNKLRFLPEFPSCSLL 267
Query: 203 SKIHTVSVDGNLFEPKQLAXL 141
++H + E + L L
Sbjct: 268 KELHVGENQIEMLEAEHLKHL 288
Score = 81.0 bits (191), Expect = 4e-15
Identities = 49/158 (31%), Positives = 93/158 (58%), Gaps = 1/158 (0%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
+LK +P ++ + L++LD + N L +P +L+ ++ L+ L L NKL+ LPE +
Sbjct: 208 ELKSLPAEINRM-KRLKHLDCNSNLLETIPPELAGMESLELLYLRRNKLRFLPE-FPSCS 265
Query: 548 KLEVLNISNNFVQTLPV-CLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKIT 372
L+ L++ N ++ L LK+LN++ + +NKL++ P +I+ L+SL+ LDLS+N I+
Sbjct: 266 LLKELHVGENQIEMLEAEHLKHLNSILVLDLRDNKLKSVPDEIILLRSLERLDLSNNDIS 325
Query: 371 EIPYGMSELYVIELNLSQNEISLIGEDLHQAPRLKILR 258
+PY + L++ L L N + I ++ ++L+
Sbjct: 326 SLPYSLGNLHLKFLALEGNPLRTIRREIISKGTQEVLK 363
Score = 73.7 bits (173), Expect = 6e-13
Identities = 42/123 (34%), Positives = 77/123 (62%), Gaps = 1/123 (0%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
+L EIP + L +++ ++DLS NKLS + +L L+ L L+L +N L +LPE + +L
Sbjct: 436 QLCEIPKRMVELKEMVSDVDLSFNKLSFISLELCVLQKLTFLDLRNNFLNSLPEEMESLV 495
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAF-PKQILGLQSLDVLDLSHNKIT 372
+L+ +N+S N + LP L + L+ + SNN++ + P+++ +++L LDL +N +
Sbjct: 496 RLQTINLSFNRFKMLPEVLYRIFTLETILISNNQVGSVDPQKMKMMENLTTLDLQNNDLL 555
Query: 371 EIP 363
+IP
Sbjct: 556 QIP 558
Score = 55.6 bits (128), Expect = 2e-07
Identities = 40/127 (31%), Positives = 68/127 (53%), Gaps = 3/127 (2%)
Frame = -2
Query: 608 QLNLDSNKLQALPESL--INLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAF 435
QLNL L +P+ + IN+ E N + +F T + +L ++ SNNKLQ+
Sbjct: 40 QLNLSGRNLSEVPQCVWRINVDIPEEANQNLSFGATERWWEQT--DLTKLIISNNKLQSL 97
Query: 434 PKQILGLQSLDVLDLSHNKITEIPYGMSELYVIE-LNLSQNEISLIGEDLHQAPRLKILR 258
+ L +L VLD+ N++T +P + EL ++ LN+S N++ ++ E++ LK L
Sbjct: 98 TDDLRLLPALTVLDIHDNQLTSLPSAIRELENLQKLNVSHNKLKILPEEITNLRNLKCLY 157
Query: 257 LDENCLS 237
L N L+
Sbjct: 158 LQHNELT 164
Score = 45.2 bits (102), Expect = 2e-04
Identities = 36/143 (25%), Positives = 68/143 (47%), Gaps = 6/143 (4%)
Frame = -2
Query: 614 LKQLNLDSNKLQALPESLINLKKLEV---LNISNNFVQTLPVCLKNLNNL-KQVYASNNK 447
LK L+ + +P+ + + K + +N S N + +P + L + V S NK
Sbjct: 401 LKILDYSDKQATLIPDEVFDAVKSNIVTSINFSKNQLCEIPKRMVELKEMVSDVDLSFNK 460
Query: 446 LQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVIE-LNLSQNEISLIGEDLHQAPRL 270
L ++ LQ L LDL +N + +P M L ++ +NLS N ++ E L++ L
Sbjct: 461 LSFISLELCVLQKLTFLDLRNNFLNSLPEEMESLVRLQTINLSFNRFKMLPEVLYRIFTL 520
Query: 269 KILRLDENCL-SLDEIKPSLLRD 204
+ + + N + S+D K ++ +
Sbjct: 521 ETILISNNQVGSVDPQKMKMMEN 543
Score = 41.5 bits (93), Expect = 0.003
Identities = 28/118 (23%), Positives = 63/118 (53%), Gaps = 1/118 (0%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQAL-PESLINLK 549
L +P ++ SL L+ ++LS N+ +LP+ L ++ L+ + + +N++ ++ P+ + ++
Sbjct: 484 LNSLPEEMESLVR-LQTINLSFNRFKMLPEVLYRIFTLETILISNNQVGSVDPQKMKMME 542
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKI 375
L L++ NN + +P L N NL+ + N + IL + +L+ ++I
Sbjct: 543 NLTTLDLQNNDLLQIPPELGNCVNLRTLLLDGNPFRVPRAAILMKGTAAILEYLRDRI 600
>BC003407-1|AAH03407.2| 581|Homo sapiens LRRC40 protein protein.
Length = 581
Score = 101 bits (242), Expect = 3e-21
Identities = 60/158 (37%), Positives = 92/158 (58%), Gaps = 1/158 (0%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTL 504
L L +S NKL L DDL L L L++ N+L +LP ++ L+ L+ LN+S+N ++ L
Sbjct: 63 LTKLIISNNKLQSLTDDLRLLPALTVLDIHDNQLTSLPSAIRELENLQKLNVSHNKLKIL 122
Query: 503 PVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSEL-YVIELN 327
P + NL NLK +Y +N+L + L +L+ LDLS+N +T +P S L ++ LN
Sbjct: 123 PEEITNLRNLKCLYLQHNELTCISEGFEQLSNLEDLDLSNNHLTTVPASFSSLSSLVRLN 182
Query: 326 LSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSL 213
LS NE+ + ++++ RLK LD N L+ I P L
Sbjct: 183 LSSNELKSLPAEINRMKRLK--HLDCNSNLLETIPPEL 218
Score = 87.0 bits (206), Expect = 6e-17
Identities = 54/172 (31%), Positives = 99/172 (57%), Gaps = 1/172 (0%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESL 561
I D +L +P + L + L+ L++S NKL +LP++++ L++LK L L N+L + E
Sbjct: 91 IHDNQLTSLPSAIREL-ENLQKLNVSHNKLKILPEEITNLRNLKCLYLQHNELTCISEGF 149
Query: 560 INLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHN 381
L LE L++SNN + T+P +L++L ++ S+N+L++ P +I ++ L LD + N
Sbjct: 150 EQLSNLEDLDLSNNHLTTVPASFSSLSSLVRLNLSSNELKSLPAEINRMKRLKHLDCNSN 209
Query: 380 KITEIPYGMSELYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDE 228
+ IP ++ + +E L L +N++ + E LK L + EN + + E
Sbjct: 210 LLETIPPELAGMESLELLYLRRNKLRFLPE-FPSCSLLKELHVGENQIEMLE 260
Score = 84.6 bits (200), Expect = 3e-16
Identities = 58/201 (28%), Positives = 104/201 (51%), Gaps = 1/201 (0%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESL 561
I++ KL+ + D+ L L LD+ N+L+ LP + +L++L++LN+ NKL+ LPE +
Sbjct: 68 ISNNKLQSLTDDL-RLLPALTVLDIHDNQLTSLPSAIRELENLQKLNVSHNKLKILPEEI 126
Query: 560 INLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHN 381
NL+ L+ L + +N + + + L+NL+ + SNN L P L SL L+LS N
Sbjct: 127 TNLRNLKCLYLQHNELTCISEGFEQLSNLEDLDLSNNHLTTVPASFSSLSSLVRLNLSSN 186
Query: 380 KITEIPYGMSELYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRD 204
++ +P ++ + ++ L+ + N + I +L L++L L N L PS
Sbjct: 187 ELKSLPAEINRMKRLKHLDCNSNLLETIPPELAGMESLELLYLRRNKLRFLPEFPSCSLL 246
Query: 203 SKIHTVSVDGNLFEPKQLAXL 141
++H + E + L L
Sbjct: 247 KELHVGENQIEMLEAEHLKHL 267
Score = 81.0 bits (191), Expect = 4e-15
Identities = 49/158 (31%), Positives = 93/158 (58%), Gaps = 1/158 (0%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
+LK +P ++ + L++LD + N L +P +L+ ++ L+ L L NKL+ LPE +
Sbjct: 187 ELKSLPAEINRM-KRLKHLDCNSNLLETIPPELAGMESLELLYLRRNKLRFLPE-FPSCS 244
Query: 548 KLEVLNISNNFVQTLPV-CLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKIT 372
L+ L++ N ++ L LK+LN++ + +NKL++ P +I+ L+SL+ LDLS+N I+
Sbjct: 245 LLKELHVGENQIEMLEAEHLKHLNSILVLDLRDNKLKSVPDEIILLRSLERLDLSNNDIS 304
Query: 371 EIPYGMSELYVIELNLSQNEISLIGEDLHQAPRLKILR 258
+PY + L++ L L N + I ++ ++L+
Sbjct: 305 SLPYSLGNLHLKFLALEGNPLRTIRREIISKGTQEVLK 342
Score = 73.7 bits (173), Expect = 6e-13
Identities = 42/123 (34%), Positives = 77/123 (62%), Gaps = 1/123 (0%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
+L EIP + L +++ ++DLS NKLS + +L L+ L L+L +N L +LPE + +L
Sbjct: 415 QLCEIPKRMVELKEMVSDVDLSFNKLSFISLELCVLQKLTFLDLRNNFLNSLPEEMESLV 474
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAF-PKQILGLQSLDVLDLSHNKIT 372
+L+ +N+S N + LP L + L+ + SNN++ + P+++ +++L LDL +N +
Sbjct: 475 RLQTINLSFNRFKMLPEVLYRIFTLETILISNNQVGSVDPQKMKMMENLTTLDLQNNDLL 534
Query: 371 EIP 363
+IP
Sbjct: 535 QIP 537
Score = 55.6 bits (128), Expect = 2e-07
Identities = 40/127 (31%), Positives = 68/127 (53%), Gaps = 3/127 (2%)
Frame = -2
Query: 608 QLNLDSNKLQALPESL--INLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAF 435
QLNL L +P+ + IN+ E N + +F T + +L ++ SNNKLQ+
Sbjct: 19 QLNLSGRNLSEVPQCVWRINVDIPEEANQNLSFGATERWWEQT--DLTKLIISNNKLQSL 76
Query: 434 PKQILGLQSLDVLDLSHNKITEIPYGMSELYVIE-LNLSQNEISLIGEDLHQAPRLKILR 258
+ L +L VLD+ N++T +P + EL ++ LN+S N++ ++ E++ LK L
Sbjct: 77 TDDLRLLPALTVLDIHDNQLTSLPSAIRELENLQKLNVSHNKLKILPEEITNLRNLKCLY 136
Query: 257 LDENCLS 237
L N L+
Sbjct: 137 LQHNELT 143
Score = 45.2 bits (102), Expect = 2e-04
Identities = 36/143 (25%), Positives = 68/143 (47%), Gaps = 6/143 (4%)
Frame = -2
Query: 614 LKQLNLDSNKLQALPESLINLKKLEV---LNISNNFVQTLPVCLKNLNNL-KQVYASNNK 447
LK L+ + +P+ + + K + +N S N + +P + L + V S NK
Sbjct: 380 LKILDYSDKQATLIPDEVFDAVKSNIVTSINFSKNQLCEIPKRMVELKEMVSDVDLSFNK 439
Query: 446 LQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVIE-LNLSQNEISLIGEDLHQAPRL 270
L ++ LQ L LDL +N + +P M L ++ +NLS N ++ E L++ L
Sbjct: 440 LSFISLELCVLQKLTFLDLRNNFLNSLPEEMESLVRLQTINLSFNRFKMLPEVLYRIFTL 499
Query: 269 KILRLDENCL-SLDEIKPSLLRD 204
+ + + N + S+D K ++ +
Sbjct: 500 ETILISNNQVGSVDPQKMKMMEN 522
Score = 41.5 bits (93), Expect = 0.003
Identities = 28/118 (23%), Positives = 63/118 (53%), Gaps = 1/118 (0%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQAL-PESLINLK 549
L +P ++ SL L+ ++LS N+ +LP+ L ++ L+ + + +N++ ++ P+ + ++
Sbjct: 463 LNSLPEEMESLVR-LQTINLSFNRFKMLPEVLYRIFTLETILISNNQVGSVDPQKMKMME 521
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKI 375
L L++ NN + +P L N NL+ + N + IL + +L+ ++I
Sbjct: 522 NLTTLDLQNNDLLQIPPELGNCVNLRTLLLDGNPFRVPRAAILMKGTAAILEYLRDRI 579
>AL353771-3|CAI22332.1| 602|Homo sapiens leucine rich repeat
containing 40 protein.
Length = 602
Score = 101 bits (242), Expect = 3e-21
Identities = 60/158 (37%), Positives = 92/158 (58%), Gaps = 1/158 (0%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTL 504
L L +S NKL L DDL L L L++ N+L +LP ++ L+ L+ LN+S+N ++ L
Sbjct: 84 LTKLIISNNKLQSLTDDLRLLPALTVLDIHDNQLTSLPSAIRELENLQKLNVSHNKLKIL 143
Query: 503 PVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSEL-YVIELN 327
P + NL NLK +Y +N+L + L +L+ LDLS+N +T +P S L ++ LN
Sbjct: 144 PEEITNLRNLKCLYLQHNELTCISEGFEQLSNLEDLDLSNNHLTTVPASFSSLSSLVRLN 203
Query: 326 LSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSL 213
LS NE+ + ++++ RLK LD N L+ I P L
Sbjct: 204 LSSNELKSLPAEINRMKRLK--HLDCNSNLLETIPPEL 239
Score = 87.0 bits (206), Expect = 6e-17
Identities = 54/172 (31%), Positives = 99/172 (57%), Gaps = 1/172 (0%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESL 561
I D +L +P + L + L+ L++S NKL +LP++++ L++LK L L N+L + E
Sbjct: 112 IHDNQLTSLPSAIREL-ENLQKLNVSHNKLKILPEEITNLRNLKCLYLQHNELTCISEGF 170
Query: 560 INLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHN 381
L LE L++SNN + T+P +L++L ++ S+N+L++ P +I ++ L LD + N
Sbjct: 171 EQLSNLEDLDLSNNHLTTVPASFSSLSSLVRLNLSSNELKSLPAEINRMKRLKHLDCNSN 230
Query: 380 KITEIPYGMSELYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDE 228
+ IP ++ + +E L L +N++ + E LK L + EN + + E
Sbjct: 231 LLETIPPELAGMESLELLYLRRNKLRFLPE-FPSCSLLKELHVGENQIEMLE 281
Score = 84.6 bits (200), Expect = 3e-16
Identities = 58/201 (28%), Positives = 104/201 (51%), Gaps = 1/201 (0%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESL 561
I++ KL+ + D+ L L LD+ N+L+ LP + +L++L++LN+ NKL+ LPE +
Sbjct: 89 ISNNKLQSLTDDL-RLLPALTVLDIHDNQLTSLPSAIRELENLQKLNVSHNKLKILPEEI 147
Query: 560 INLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHN 381
NL+ L+ L + +N + + + L+NL+ + SNN L P L SL L+LS N
Sbjct: 148 TNLRNLKCLYLQHNELTCISEGFEQLSNLEDLDLSNNHLTTVPASFSSLSSLVRLNLSSN 207
Query: 380 KITEIPYGMSELYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRD 204
++ +P ++ + ++ L+ + N + I +L L++L L N L PS
Sbjct: 208 ELKSLPAEINRMKRLKHLDCNSNLLETIPPELAGMESLELLYLRRNKLRFLPEFPSCSLL 267
Query: 203 SKIHTVSVDGNLFEPKQLAXL 141
++H + E + L L
Sbjct: 268 KELHVGENQIEMLEAEHLKHL 288
Score = 81.0 bits (191), Expect = 4e-15
Identities = 49/158 (31%), Positives = 93/158 (58%), Gaps = 1/158 (0%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
+LK +P ++ + L++LD + N L +P +L+ ++ L+ L L NKL+ LPE +
Sbjct: 208 ELKSLPAEINRM-KRLKHLDCNSNLLETIPPELAGMESLELLYLRRNKLRFLPE-FPSCS 265
Query: 548 KLEVLNISNNFVQTLPV-CLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKIT 372
L+ L++ N ++ L LK+LN++ + +NKL++ P +I+ L+SL+ LDLS+N I+
Sbjct: 266 LLKELHVGENQIEMLEAEHLKHLNSILVLDLRDNKLKSVPDEIILLRSLERLDLSNNDIS 325
Query: 371 EIPYGMSELYVIELNLSQNEISLIGEDLHQAPRLKILR 258
+PY + L++ L L N + I ++ ++L+
Sbjct: 326 SLPYSLGNLHLKFLALEGNPLRTIRREIISKGTQEVLK 363
Score = 73.7 bits (173), Expect = 6e-13
Identities = 42/123 (34%), Positives = 77/123 (62%), Gaps = 1/123 (0%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
+L EIP + L +++ ++DLS NKLS + +L L+ L L+L +N L +LPE + +L
Sbjct: 436 QLCEIPKRMVELKEMVSDVDLSFNKLSFISLELCVLQKLTFLDLRNNFLNSLPEEMESLV 495
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAF-PKQILGLQSLDVLDLSHNKIT 372
+L+ +N+S N + LP L + L+ + SNN++ + P+++ +++L LDL +N +
Sbjct: 496 RLQTINLSFNRFKMLPEVLYRIFTLETILISNNQVGSVDPQKMKMMENLTTLDLQNNDLL 555
Query: 371 EIP 363
+IP
Sbjct: 556 QIP 558
Score = 55.6 bits (128), Expect = 2e-07
Identities = 40/127 (31%), Positives = 68/127 (53%), Gaps = 3/127 (2%)
Frame = -2
Query: 608 QLNLDSNKLQALPESL--INLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAF 435
QLNL L +P+ + IN+ E N + +F T + +L ++ SNNKLQ+
Sbjct: 40 QLNLSGRNLSEVPQCVWRINVDIPEEANQNLSFGATERWWEQT--DLTKLIISNNKLQSL 97
Query: 434 PKQILGLQSLDVLDLSHNKITEIPYGMSELYVIE-LNLSQNEISLIGEDLHQAPRLKILR 258
+ L +L VLD+ N++T +P + EL ++ LN+S N++ ++ E++ LK L
Sbjct: 98 TDDLRLLPALTVLDIHDNQLTSLPSAIRELENLQKLNVSHNKLKILPEEITNLRNLKCLY 157
Query: 257 LDENCLS 237
L N L+
Sbjct: 158 LQHNELT 164
Score = 45.2 bits (102), Expect = 2e-04
Identities = 36/143 (25%), Positives = 68/143 (47%), Gaps = 6/143 (4%)
Frame = -2
Query: 614 LKQLNLDSNKLQALPESLINLKKLEV---LNISNNFVQTLPVCLKNLNNL-KQVYASNNK 447
LK L+ + +P+ + + K + +N S N + +P + L + V S NK
Sbjct: 401 LKILDYSDKQATLIPDEVFDAVKSNIVTSINFSKNQLCEIPKRMVELKEMVSDVDLSFNK 460
Query: 446 LQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVIE-LNLSQNEISLIGEDLHQAPRL 270
L ++ LQ L LDL +N + +P M L ++ +NLS N ++ E L++ L
Sbjct: 461 LSFISLELCVLQKLTFLDLRNNFLNSLPEEMESLVRLQTINLSFNRFKMLPEVLYRIFTL 520
Query: 269 KILRLDENCL-SLDEIKPSLLRD 204
+ + + N + S+D K ++ +
Sbjct: 521 ETILISNNQVGSVDPQKMKMMEN 543
Score = 41.5 bits (93), Expect = 0.003
Identities = 28/118 (23%), Positives = 63/118 (53%), Gaps = 1/118 (0%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQAL-PESLINLK 549
L +P ++ SL L+ ++LS N+ +LP+ L ++ L+ + + +N++ ++ P+ + ++
Sbjct: 484 LNSLPEEMESLVR-LQTINLSFNRFKMLPEVLYRIFTLETILISNNQVGSVDPQKMKMME 542
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKI 375
L L++ NN + +P L N NL+ + N + IL + +L+ ++I
Sbjct: 543 NLTTLDLQNNDLLQIPPELGNCVNLRTLLLDGNPFRVPRAAILMKGTAAILEYLRDRI 600
>AK022951-1|BAB14326.1| 602|Homo sapiens protein ( Homo sapiens
cDNA FLJ12889 fis, clone NT2RP2004098, weakly similar to
ADENYLATE CYCLASE (EC 4.6.1.1). ).
Length = 602
Score = 101 bits (242), Expect = 3e-21
Identities = 60/158 (37%), Positives = 92/158 (58%), Gaps = 1/158 (0%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTL 504
L L +S NKL L DDL L L L++ N+L +LP ++ L+ L+ LN+S+N ++ L
Sbjct: 84 LTKLIISNNKLQSLTDDLRLLPALTVLDIHDNQLTSLPSAIRELENLQKLNVSHNKLKIL 143
Query: 503 PVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSEL-YVIELN 327
P + NL NLK +Y +N+L + L +L+ LDLS+N +T +P S L ++ LN
Sbjct: 144 PEEITNLRNLKCLYLQHNELTCISEGFEQLSNLEDLDLSNNHLTTVPASFSSLSSLVRLN 203
Query: 326 LSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSL 213
LS NE+ + ++++ RLK LD N L+ I P L
Sbjct: 204 LSSNELKSLPAEINRMKRLK--HLDCNSNLLETIPPEL 239
Score = 87.0 bits (206), Expect = 6e-17
Identities = 54/172 (31%), Positives = 99/172 (57%), Gaps = 1/172 (0%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESL 561
I D +L +P + L + L+ L++S NKL +LP++++ L++LK L L N+L + E
Sbjct: 112 IHDNQLTSLPSAIREL-ENLQKLNVSHNKLKILPEEITNLRNLKCLYLQHNELTCISEGF 170
Query: 560 INLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHN 381
L LE L++SNN + T+P +L++L ++ S+N+L++ P +I ++ L LD + N
Sbjct: 171 EQLSNLEDLDLSNNHLTTVPASFSSLSSLVRLNLSSNELKSLPAEINRMKRLKHLDCNSN 230
Query: 380 KITEIPYGMSELYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDE 228
+ IP ++ + +E L L +N++ + E LK L + EN + + E
Sbjct: 231 LLETIPPELAGMESLELLYLRRNKLRFLPE-FPSCSLLKELHVGENQIEMLE 281
Score = 84.6 bits (200), Expect = 3e-16
Identities = 58/201 (28%), Positives = 104/201 (51%), Gaps = 1/201 (0%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESL 561
I++ KL+ + D+ L L LD+ N+L+ LP + +L++L++LN+ NKL+ LPE +
Sbjct: 89 ISNNKLQSLTDDL-RLLPALTVLDIHDNQLTSLPSAIRELENLQKLNVSHNKLKILPEEI 147
Query: 560 INLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHN 381
NL+ L+ L + +N + + + L+NL+ + SNN L P L SL L+LS N
Sbjct: 148 TNLRNLKCLYLQHNELTCISEGFEQLSNLEDLDLSNNHLTTVPASFSSLSSLVRLNLSSN 207
Query: 380 KITEIPYGMSELYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRD 204
++ +P ++ + ++ L+ + N + I +L L++L L N L PS
Sbjct: 208 ELKSLPAEINRMKRLKHLDCNSNLLETIPPELAGMESLELLYLRRNKLRFLPEFPSCSLL 267
Query: 203 SKIHTVSVDGNLFEPKQLAXL 141
++H + E + L L
Sbjct: 268 KELHVGENQIEMLEAEHLKHL 288
Score = 81.0 bits (191), Expect = 4e-15
Identities = 49/158 (31%), Positives = 93/158 (58%), Gaps = 1/158 (0%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
+LK +P ++ + L++LD + N L +P +L+ ++ L+ L L NKL+ LPE +
Sbjct: 208 ELKSLPAEINRM-KRLKHLDCNSNLLETIPPELAGMESLELLYLRRNKLRFLPE-FPSCS 265
Query: 548 KLEVLNISNNFVQTLPV-CLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKIT 372
L+ L++ N ++ L LK+LN++ + +NKL++ P +I+ L+SL+ LDLS+N I+
Sbjct: 266 LLKELHVGENQIEMLEAEHLKHLNSILVLDLRDNKLKSVPDEIILLRSLERLDLSNNDIS 325
Query: 371 EIPYGMSELYVIELNLSQNEISLIGEDLHQAPRLKILR 258
+PY + L++ L L N + I ++ ++L+
Sbjct: 326 SLPYSLGNLHLKFLALEGNPLRTIRREIISKGTQEVLK 363
Score = 73.7 bits (173), Expect = 6e-13
Identities = 42/123 (34%), Positives = 77/123 (62%), Gaps = 1/123 (0%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
+L EIP + L +++ ++DLS NKLS + +L L+ L L+L +N L +LPE + +L
Sbjct: 436 QLCEIPKRMVELKEMVSDVDLSFNKLSFISLELCVLQKLTFLDLRNNFLNSLPEEMESLV 495
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAF-PKQILGLQSLDVLDLSHNKIT 372
+L+ +N+S N + LP L + L+ + SNN++ + P+++ +++L LDL +N +
Sbjct: 496 RLQTINLSFNRFKMLPEVLYRIFTLETILISNNQVGSVDPQKMKMMENLTTLDLQNNDLL 555
Query: 371 EIP 363
+IP
Sbjct: 556 QIP 558
Score = 55.6 bits (128), Expect = 2e-07
Identities = 40/127 (31%), Positives = 68/127 (53%), Gaps = 3/127 (2%)
Frame = -2
Query: 608 QLNLDSNKLQALPESL--INLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAF 435
QLNL L +P+ + IN+ E N + +F T + +L ++ SNNKLQ+
Sbjct: 40 QLNLSGRNLSEVPQCVWRINVDIPEEANQNLSFGATERWWEQT--DLTKLIISNNKLQSL 97
Query: 434 PKQILGLQSLDVLDLSHNKITEIPYGMSELYVIE-LNLSQNEISLIGEDLHQAPRLKILR 258
+ L +L VLD+ N++T +P + EL ++ LN+S N++ ++ E++ LK L
Sbjct: 98 TDDLRLLPALTVLDIHDNQLTSLPSAIRELENLQKLNVSHNKLKILPEEITNLRNLKCLY 157
Query: 257 LDENCLS 237
L N L+
Sbjct: 158 LQHNELT 164
Score = 45.2 bits (102), Expect = 2e-04
Identities = 36/143 (25%), Positives = 68/143 (47%), Gaps = 6/143 (4%)
Frame = -2
Query: 614 LKQLNLDSNKLQALPESLINLKKLEV---LNISNNFVQTLPVCLKNLNNL-KQVYASNNK 447
LK L+ + +P+ + + K + +N S N + +P + L + V S NK
Sbjct: 401 LKILDYSDKQATLIPDEVFDAVKSNIVTSINFSKNQLCEIPKRMVELKEMVSDVDLSFNK 460
Query: 446 LQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVIE-LNLSQNEISLIGEDLHQAPRL 270
L ++ LQ L LDL +N + +P M L ++ +NLS N ++ E L++ L
Sbjct: 461 LSFISLELCVLQKLTFLDLRNNFLNSLPEEMESLVRLQTINLSFNRFKMLPEVLYRIFTL 520
Query: 269 KILRLDENCL-SLDEIKPSLLRD 204
+ + + N + S+D K ++ +
Sbjct: 521 ETILISNNQVGSVDPQKMKMMEN 543
Score = 41.5 bits (93), Expect = 0.003
Identities = 28/118 (23%), Positives = 63/118 (53%), Gaps = 1/118 (0%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQAL-PESLINLK 549
L +P ++ SL L+ ++LS N+ +LP+ L ++ L+ + + +N++ ++ P+ + ++
Sbjct: 484 LNSLPEEMESLVR-LQTINLSFNRFKMLPEVLYRIFTLETILISNNQVGSVDPQKMKMME 542
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKI 375
L L++ NN + +P L N NL+ + N + IL + +L+ ++I
Sbjct: 543 NLTTLDLQNNDLLQIPPELGNCVNLRTLLLDGNPFRVPRAAILMKGTAAILEYLRDRI 600
>BC117472-1|AAI17473.1| 763|Homo sapiens LRCH1 protein protein.
Length = 763
Score = 97.5 bits (232), Expect = 4e-20
Identities = 61/158 (38%), Positives = 95/158 (60%), Gaps = 4/158 (2%)
Frame = -2
Query: 728 KLKEIPIDV---FSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLI 558
KLKE P L D ++ DLSKN+L +P +L L+ LNL N ++ +PE+++
Sbjct: 82 KLKEFPRTAAPGHDLSDTVQ-ADLSKNRLVEVPMELCHFVSLEILNLYHNCIRVIPEAIV 140
Query: 557 NLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNK 378
NL+ L LN+S N + LP CL L LK + ASNNKL + P++I L+ L LD+S N+
Sbjct: 141 NLQMLTYLNLSRNQLSALPACLCGL-PLKVLIASNNKLGSLPEEIGQLKQLMELDVSCNE 199
Query: 377 ITEIPYGMSELYVI-ELNLSQNEISLIGEDLHQAPRLK 267
IT +P + +L + ELN+ +N + ++ ++L P +K
Sbjct: 200 ITALPQQIGQLKSLRELNVRRNYLKVLPQELVDLPLVK 237
Score = 80.2 bits (189), Expect = 7e-15
Identities = 52/163 (31%), Positives = 92/163 (56%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
+L E+P+++ L L+L N + V+P+ + L+ L LNL N+L ALP L L
Sbjct: 108 RLVEVPMELCHFVS-LEILNLYHNCIRVIPEAIVNLQMLTYLNLSRNQLSALPACLCGLP 166
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITE 369
L+VL SNN + +LP + L L ++ S N++ A P+QI L+SL L++ N +
Sbjct: 167 -LKVLIASNNKLGSLPEEIGQLKQLMELDVSCNEITALPQQIGQLKSLRELNVRRNYLKV 225
Query: 368 IPYGMSELYVIELNLSQNEISLIGEDLHQAPRLKILRLDENCL 240
+P + +L +++ + S N++ +I + +L++L L+ N L
Sbjct: 226 LPQELVDLPLVKFDFSCNKVLVIPICFREMKQLQVLLLENNPL 268
Score = 66.9 bits (156), Expect = 7e-11
Identities = 34/102 (33%), Positives = 62/102 (60%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
KL +P ++ L ++ LD+S N+++ LP + +LK L++LN+ N L+ LP+ L++L
Sbjct: 176 KLGSLPEEIGQLKQLME-LDVSCNEITALPQQIGQLKSLRELNVRRNYLKVLPQELVDLP 234
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQI 423
++ + S N V +P+C + + L+ + NN LQ+ P QI
Sbjct: 235 LVK-FDFSCNKVLVIPICFREMKQLQVLLLENNPLQSPPAQI 275
Score = 64.1 bits (149), Expect = 5e-10
Identities = 39/112 (34%), Positives = 64/112 (57%), Gaps = 1/112 (0%)
Frame = -2
Query: 695 LCDV-LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNN 519
LC + L+ L S NKL LP+++ +LK L +L++ N++ ALP+ + LK L LN+ N
Sbjct: 162 LCGLPLKVLIASNNKLGSLPEEIGQLKQLMELDVSCNEITALPQQIGQLKSLRELNVRRN 221
Query: 518 FVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIP 363
+++ LP L +L +K + S NK+ P ++ L VL L +N + P
Sbjct: 222 YLKVLPQELVDLPLVKFDF-SCNKVLVIPICFREMKQLQVLLLENNPLQSPP 272
Score = 32.7 bits (71), Expect = 1.4
Identities = 20/63 (31%), Positives = 34/63 (53%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKK 546
LK +P ++ L L D S NK+ V+P ++K L+ L L++N LQ+ P + K
Sbjct: 223 LKVLPQELVDL--PLVKFDFSCNKVLVIPICFREMKQLQVLLLENNPLQSPPAQICTKGK 280
Query: 545 LEV 537
+ +
Sbjct: 281 VHI 283
>BC112937-1|AAI12938.1| 696|Homo sapiens LRCH1 protein protein.
Length = 696
Score = 97.5 bits (232), Expect = 4e-20
Identities = 61/158 (38%), Positives = 95/158 (60%), Gaps = 4/158 (2%)
Frame = -2
Query: 728 KLKEIPIDV---FSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLI 558
KLKE P L D ++ DLSKN+L +P +L L+ LNL N ++ +PE+++
Sbjct: 82 KLKEFPRTAAPGHDLSDTVQ-ADLSKNRLVEVPMELCHFVSLEILNLYHNCIRVIPEAIV 140
Query: 557 NLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNK 378
NL+ L LN+S N + LP CL L LK + ASNNKL + P++I L+ L LD+S N+
Sbjct: 141 NLQMLTYLNLSRNQLSALPACLCGL-PLKVLIASNNKLGSLPEEIGQLKQLMELDVSCNE 199
Query: 377 ITEIPYGMSELYVI-ELNLSQNEISLIGEDLHQAPRLK 267
IT +P + +L + ELN+ +N + ++ ++L P +K
Sbjct: 200 ITALPQQIGQLKSLRELNVRRNYLKVLPQELVDLPLVK 237
Score = 80.2 bits (189), Expect = 7e-15
Identities = 52/163 (31%), Positives = 92/163 (56%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
+L E+P+++ L L+L N + V+P+ + L+ L LNL N+L ALP L L
Sbjct: 108 RLVEVPMELCHFVS-LEILNLYHNCIRVIPEAIVNLQMLTYLNLSRNQLSALPACLCGLP 166
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITE 369
L+VL SNN + +LP + L L ++ S N++ A P+QI L+SL L++ N +
Sbjct: 167 -LKVLIASNNKLGSLPEEIGQLKQLMELDVSCNEITALPQQIGQLKSLRELNVRRNYLKV 225
Query: 368 IPYGMSELYVIELNLSQNEISLIGEDLHQAPRLKILRLDENCL 240
+P + +L +++ + S N++ +I + +L++L L+ N L
Sbjct: 226 LPQELVDLPLVKFDFSCNKVLVIPICFREMKQLQVLLLENNPL 268
Score = 66.9 bits (156), Expect = 7e-11
Identities = 34/102 (33%), Positives = 62/102 (60%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
KL +P ++ L ++ LD+S N+++ LP + +LK L++LN+ N L+ LP+ L++L
Sbjct: 176 KLGSLPEEIGQLKQLME-LDVSCNEITALPQQIGQLKSLRELNVRRNYLKVLPQELVDLP 234
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQI 423
++ + S N V +P+C + + L+ + NN LQ+ P QI
Sbjct: 235 LVK-FDFSCNKVLVIPICFREMKQLQVLLLENNPLQSPPAQI 275
Score = 64.1 bits (149), Expect = 5e-10
Identities = 39/112 (34%), Positives = 64/112 (57%), Gaps = 1/112 (0%)
Frame = -2
Query: 695 LCDV-LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNN 519
LC + L+ L S NKL LP+++ +LK L +L++ N++ ALP+ + LK L LN+ N
Sbjct: 162 LCGLPLKVLIASNNKLGSLPEEIGQLKQLMELDVSCNEITALPQQIGQLKSLRELNVRRN 221
Query: 518 FVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIP 363
+++ LP L +L +K + S NK+ P ++ L VL L +N + P
Sbjct: 222 YLKVLPQELVDLPLVKFDF-SCNKVLVIPICFREMKQLQVLLLENNPLQSPP 272
Score = 32.7 bits (71), Expect = 1.4
Identities = 20/63 (31%), Positives = 34/63 (53%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKK 546
LK +P ++ L L D S NK+ V+P ++K L+ L L++N LQ+ P + K
Sbjct: 223 LKVLPQELVDL--PLVKFDFSCNKVLVIPICFREMKQLQVLLLENNPLQSPPAQICTKGK 280
Query: 545 LEV 537
+ +
Sbjct: 281 VHI 283
>AY050632-1|AAK95568.1| 728|Homo sapiens neuronal protein isoform B
protein.
Length = 728
Score = 97.5 bits (232), Expect = 4e-20
Identities = 61/158 (38%), Positives = 95/158 (60%), Gaps = 4/158 (2%)
Frame = -2
Query: 728 KLKEIPIDV---FSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLI 558
KLKE P L D ++ DLSKN+L +P +L L+ LNL N ++ +PE+++
Sbjct: 82 KLKEFPRTAAPGHDLSDTVQ-ADLSKNRLVEVPMELCHFVSLEILNLYHNCIRVIPEAIV 140
Query: 557 NLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNK 378
NL+ L LN+S N + LP CL L LK + ASNNKL + P++I L+ L LD+S N+
Sbjct: 141 NLQMLTYLNLSRNQLSALPACLCGL-PLKVLIASNNKLGSLPEEIGQLKQLMELDVSCNE 199
Query: 377 ITEIPYGMSELYVI-ELNLSQNEISLIGEDLHQAPRLK 267
IT +P + +L + ELN+ +N + ++ ++L P +K
Sbjct: 200 ITALPQQIGQLKSLRELNVRRNYLKVLPQELVDLPLVK 237
Score = 80.2 bits (189), Expect = 7e-15
Identities = 52/163 (31%), Positives = 92/163 (56%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
+L E+P+++ L L+L N + V+P+ + L+ L LNL N+L ALP L L
Sbjct: 108 RLVEVPMELCHFVS-LEILNLYHNCIRVIPEAIVNLQMLTYLNLSRNQLSALPACLCGLP 166
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITE 369
L+VL SNN + +LP + L L ++ S N++ A P+QI L+SL L++ N +
Sbjct: 167 -LKVLIASNNKLGSLPEEIGQLKQLMELDVSCNEITALPQQIGQLKSLRELNVRRNYLKV 225
Query: 368 IPYGMSELYVIELNLSQNEISLIGEDLHQAPRLKILRLDENCL 240
+P + +L +++ + S N++ +I + +L++L L+ N L
Sbjct: 226 LPQELVDLPLVKFDFSCNKVLVIPICFREMKQLQVLLLENNPL 268
Score = 66.9 bits (156), Expect = 7e-11
Identities = 34/102 (33%), Positives = 62/102 (60%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
KL +P ++ L ++ LD+S N+++ LP + +LK L++LN+ N L+ LP+ L++L
Sbjct: 176 KLGSLPEEIGQLKQLME-LDVSCNEITALPQQIGQLKSLRELNVRRNYLKVLPQELVDLP 234
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQI 423
++ + S N V +P+C + + L+ + NN LQ+ P QI
Sbjct: 235 LVK-FDFSCNKVLVIPICFREMKQLQVLLLENNPLQSPPAQI 275
Score = 64.1 bits (149), Expect = 5e-10
Identities = 39/112 (34%), Positives = 64/112 (57%), Gaps = 1/112 (0%)
Frame = -2
Query: 695 LCDV-LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNN 519
LC + L+ L S NKL LP+++ +LK L +L++ N++ ALP+ + LK L LN+ N
Sbjct: 162 LCGLPLKVLIASNNKLGSLPEEIGQLKQLMELDVSCNEITALPQQIGQLKSLRELNVRRN 221
Query: 518 FVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIP 363
+++ LP L +L +K + S NK+ P ++ L VL L +N + P
Sbjct: 222 YLKVLPQELVDLPLVKFDF-SCNKVLVIPICFREMKQLQVLLLENNPLQSPP 272
Score = 32.7 bits (71), Expect = 1.4
Identities = 20/63 (31%), Positives = 34/63 (53%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKK 546
LK +P ++ L L D S NK+ V+P ++K L+ L L++N LQ+ P + K
Sbjct: 223 LKVLPQELVDL--PLVKFDFSCNKVLVIPICFREMKQLQVLLLENNPLQSPPAQICTKGK 280
Query: 545 LEV 537
+ +
Sbjct: 281 VHI 283
>AY050631-1|AAK95567.1| 696|Homo sapiens neuronal protein isoform a
protein.
Length = 696
Score = 97.5 bits (232), Expect = 4e-20
Identities = 61/158 (38%), Positives = 95/158 (60%), Gaps = 4/158 (2%)
Frame = -2
Query: 728 KLKEIPIDV---FSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLI 558
KLKE P L D ++ DLSKN+L +P +L L+ LNL N ++ +PE+++
Sbjct: 82 KLKEFPRTAAPGHDLSDTVQ-ADLSKNRLVEVPMELCHFVSLEILNLYHNCIRVIPEAIV 140
Query: 557 NLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNK 378
NL+ L LN+S N + LP CL L LK + ASNNKL + P++I L+ L LD+S N+
Sbjct: 141 NLQMLTYLNLSRNQLSALPACLCGL-PLKVLIASNNKLGSLPEEIGQLKQLMELDVSCNE 199
Query: 377 ITEIPYGMSELYVI-ELNLSQNEISLIGEDLHQAPRLK 267
IT +P + +L + ELN+ +N + ++ ++L P +K
Sbjct: 200 ITALPQQIGQLKSLRELNVRRNYLKVLPQELVDLPLVK 237
Score = 80.2 bits (189), Expect = 7e-15
Identities = 52/163 (31%), Positives = 92/163 (56%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
+L E+P+++ L L+L N + V+P+ + L+ L LNL N+L ALP L L
Sbjct: 108 RLVEVPMELCHFVS-LEILNLYHNCIRVIPEAIVNLQMLTYLNLSRNQLSALPACLCGLP 166
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITE 369
L+VL SNN + +LP + L L ++ S N++ A P+QI L+SL L++ N +
Sbjct: 167 -LKVLIASNNKLGSLPEEIGQLKQLMELDVSCNEITALPQQIGQLKSLRELNVRRNYLKV 225
Query: 368 IPYGMSELYVIELNLSQNEISLIGEDLHQAPRLKILRLDENCL 240
+P + +L +++ + S N++ +I + +L++L L+ N L
Sbjct: 226 LPQELVDLPLVKFDFSCNKVLVIPICFREMKQLQVLLLENNPL 268
Score = 66.9 bits (156), Expect = 7e-11
Identities = 34/102 (33%), Positives = 62/102 (60%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
KL +P ++ L ++ LD+S N+++ LP + +LK L++LN+ N L+ LP+ L++L
Sbjct: 176 KLGSLPEEIGQLKQLME-LDVSCNEITALPQQIGQLKSLRELNVRRNYLKVLPQELVDLP 234
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQI 423
++ + S N V +P+C + + L+ + NN LQ+ P QI
Sbjct: 235 LVK-FDFSCNKVLVIPICFREMKQLQVLLLENNPLQSPPAQI 275
Score = 64.1 bits (149), Expect = 5e-10
Identities = 39/112 (34%), Positives = 64/112 (57%), Gaps = 1/112 (0%)
Frame = -2
Query: 695 LCDV-LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNN 519
LC + L+ L S NKL LP+++ +LK L +L++ N++ ALP+ + LK L LN+ N
Sbjct: 162 LCGLPLKVLIASNNKLGSLPEEIGQLKQLMELDVSCNEITALPQQIGQLKSLRELNVRRN 221
Query: 518 FVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIP 363
+++ LP L +L +K + S NK+ P ++ L VL L +N + P
Sbjct: 222 YLKVLPQELVDLPLVKFDF-SCNKVLVIPICFREMKQLQVLLLENNPLQSPP 272
Score = 32.7 bits (71), Expect = 1.4
Identities = 20/63 (31%), Positives = 34/63 (53%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKK 546
LK +P ++ L L D S NK+ V+P ++K L+ L L++N LQ+ P + K
Sbjct: 223 LKVLPQELVDL--PLVKFDFSCNKVLVIPICFREMKQLQVLLLENNPLQSPPAQICTKGK 280
Query: 545 LEV 537
+ +
Sbjct: 281 VHI 283
>AB023233-1|BAA76860.1| 793|Homo sapiens KIAA1016 protein protein.
Length = 793
Score = 97.5 bits (232), Expect = 4e-20
Identities = 61/158 (38%), Positives = 95/158 (60%), Gaps = 4/158 (2%)
Frame = -2
Query: 728 KLKEIPIDV---FSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLI 558
KLKE P L D ++ DLSKN+L +P +L L+ LNL N ++ +PE+++
Sbjct: 147 KLKEFPRTAAPGHDLSDTVQ-ADLSKNRLVEVPMELCHFVSLEILNLYHNCIRVIPEAIV 205
Query: 557 NLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNK 378
NL+ L LN+S N + LP CL L LK + ASNNKL + P++I L+ L LD+S N+
Sbjct: 206 NLQMLTYLNLSRNQLSALPACLCGL-PLKVLIASNNKLGSLPEEIGQLKQLMELDVSCNE 264
Query: 377 ITEIPYGMSELYVI-ELNLSQNEISLIGEDLHQAPRLK 267
IT +P + +L + ELN+ +N + ++ ++L P +K
Sbjct: 265 ITALPQQIGQLKSLRELNVRRNYLKVLPQELVDLPLVK 302
Score = 80.2 bits (189), Expect = 7e-15
Identities = 52/163 (31%), Positives = 92/163 (56%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
+L E+P+++ L L+L N + V+P+ + L+ L LNL N+L ALP L L
Sbjct: 173 RLVEVPMELCHFVS-LEILNLYHNCIRVIPEAIVNLQMLTYLNLSRNQLSALPACLCGLP 231
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITE 369
L+VL SNN + +LP + L L ++ S N++ A P+QI L+SL L++ N +
Sbjct: 232 -LKVLIASNNKLGSLPEEIGQLKQLMELDVSCNEITALPQQIGQLKSLRELNVRRNYLKV 290
Query: 368 IPYGMSELYVIELNLSQNEISLIGEDLHQAPRLKILRLDENCL 240
+P + +L +++ + S N++ +I + +L++L L+ N L
Sbjct: 291 LPQELVDLPLVKFDFSCNKVLVIPICFREMKQLQVLLLENNPL 333
Score = 66.9 bits (156), Expect = 7e-11
Identities = 34/102 (33%), Positives = 62/102 (60%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
KL +P ++ L ++ LD+S N+++ LP + +LK L++LN+ N L+ LP+ L++L
Sbjct: 241 KLGSLPEEIGQLKQLME-LDVSCNEITALPQQIGQLKSLRELNVRRNYLKVLPQELVDLP 299
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQI 423
++ + S N V +P+C + + L+ + NN LQ+ P QI
Sbjct: 300 LVK-FDFSCNKVLVIPICFREMKQLQVLLLENNPLQSPPAQI 340
Score = 64.1 bits (149), Expect = 5e-10
Identities = 39/112 (34%), Positives = 64/112 (57%), Gaps = 1/112 (0%)
Frame = -2
Query: 695 LCDV-LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNN 519
LC + L+ L S NKL LP+++ +LK L +L++ N++ ALP+ + LK L LN+ N
Sbjct: 227 LCGLPLKVLIASNNKLGSLPEEIGQLKQLMELDVSCNEITALPQQIGQLKSLRELNVRRN 286
Query: 518 FVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIP 363
+++ LP L +L +K + S NK+ P ++ L VL L +N + P
Sbjct: 287 YLKVLPQELVDLPLVKFDF-SCNKVLVIPICFREMKQLQVLLLENNPLQSPP 337
Score = 32.7 bits (71), Expect = 1.4
Identities = 20/63 (31%), Positives = 34/63 (53%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKK 546
LK +P ++ L L D S NK+ V+P ++K L+ L L++N LQ+ P + K
Sbjct: 288 LKVLPQELVDL--PLVKFDFSCNKVLVIPICFREMKQLQVLLLENNPLQSPPAQICTKGK 345
Query: 545 LEV 537
+ +
Sbjct: 346 VHI 348
>BC024159-1|AAH24159.2| 858|Homo sapiens leucine rich repeat
containing 8 family, member D protein.
Length = 858
Score = 96.7 bits (230), Expect = 8e-20
Identities = 67/208 (32%), Positives = 110/208 (52%), Gaps = 3/208 (1%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLS--KLKHLKQLNLDSNKLQALPE 567
+ +C+L+ IP +FSL + L+ LDL N + + + +S LK L L L NK+ +P
Sbjct: 642 LQNCELERIPHAIFSLSN-LQELDLKSNNIRTIEEIISFQHLKRLTCLKLWHNKIVTIPP 700
Query: 566 SLINLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLS 387
S+ ++K LE L SNN +++LPV + +L L+ + S N + P +I LQ+L L ++
Sbjct: 701 SITHVKNLESLYFSNNKLESLPVAVFSLQKLRCLDVSYNNISMIPIEIGLLQNLQHLHIT 760
Query: 386 HNKITEIPYGMSELYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLL 210
NK+ +P + + + LNL QN I+ + E + Q +L L L NCL +
Sbjct: 761 GNKVDILPKQLFKCIKLRTLNLGQNCITSLPEKVGQLSQLTQLELKGNCLDRLPAQLGQC 820
Query: 209 RDSKIHTVSVDGNLFEPKQLAXLEGYNE 126
R K + V+ +LF+ L E N+
Sbjct: 821 RMLKKSGLVVEDHLFDTLPLEVKEALNQ 848
Score = 93.1 bits (221), Expect = 1e-18
Identities = 57/181 (31%), Positives = 106/181 (58%), Gaps = 6/181 (3%)
Frame = -2
Query: 674 LDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPE--SLINLKKLEVLNISNNFVQTLP 501
L+L +L +P + L +L++L+L SN ++ + E S +LK+L L + +N + T+P
Sbjct: 640 LELQNCELERIPHAIFSLSNLQELDLKSNNIRTIEEIISFQHLKRLTCLKLWHNKIVTIP 699
Query: 500 VCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVIE-LNL 324
+ ++ NL+ +Y SNNKL++ P + LQ L LD+S+N I+ IP + L ++ L++
Sbjct: 700 PSITHVKNLESLYFSNNKLESLPVAVFSLQKLRCLDVSYNNISMIPIEIGLLQNLQHLHI 759
Query: 323 SQNEISLIGEDLHQAPRLKILRLDENCL-SLDEIKPSLLRDSKIHTVSVDGNLFE--PKQ 153
+ N++ ++ + L + +L+ L L +NC+ SL E L S++ + + GN + P Q
Sbjct: 760 TGNKVDILPKQLFKCIKLRTLNLGQNCITSLPEKVGQL---SQLTQLELKGNCLDRLPAQ 816
Query: 152 L 150
L
Sbjct: 817 L 817
Score = 33.5 bits (73), Expect = 0.81
Identities = 30/121 (24%), Positives = 55/121 (45%), Gaps = 8/121 (6%)
Frame = -2
Query: 584 LQALPESLINLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQS- 408
L +P+++ +L L+VL + +P + + NL++++ + + L+
Sbjct: 479 LSGVPDAVFDLTDLDVLKLELIPEAKIPAKISQMTNLQELHLCHCPAKVEQTAFSFLRDH 538
Query: 407 LDVLDLSHNKITEIPY------GMSELYVIELNLSQNEISLIG-EDLHQAPRLKILRLDE 249
L L + + EIP + ELY+I NL+ +IG E L + LKIL +
Sbjct: 539 LRCLHVKFTDVAEIPAWVYLLKNLRELYLIG-NLNSENNKMIGLESLRELRHLKILHVKS 597
Query: 248 N 246
N
Sbjct: 598 N 598
>AY358874-1|AAQ89233.1| 501|Homo sapiens LRRC5 protein.
Length = 501
Score = 96.7 bits (230), Expect = 8e-20
Identities = 67/208 (32%), Positives = 110/208 (52%), Gaps = 3/208 (1%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLS--KLKHLKQLNLDSNKLQALPE 567
+ +C+L+ IP +FSL + L+ LDL N + + + +S LK L L L NK+ +P
Sbjct: 285 LQNCELERIPHAIFSLSN-LQELDLKSNNIRTIEEIISFQHLKRLTCLKLWHNKIVTIPP 343
Query: 566 SLINLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLS 387
S+ ++K LE L SNN +++LPV + +L L+ + S N + P +I LQ+L L ++
Sbjct: 344 SITHVKNLESLYFSNNKLESLPVAVFSLQKLRCLDVSYNNISMIPIEIGLLQNLQHLHIT 403
Query: 386 HNKITEIPYGMSELYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLL 210
NK+ +P + + + LNL QN I+ + E + Q +L L L NCL +
Sbjct: 404 GNKVDILPKQLFKCIKLRTLNLGQNCITSLPEKVGQLSQLTQLELKGNCLDRLPAQLGQC 463
Query: 209 RDSKIHTVSVDGNLFEPKQLAXLEGYNE 126
R K + V+ +LF+ L E N+
Sbjct: 464 RMLKKSGLVVEDHLFDTLPLEVKEALNQ 491
Score = 93.1 bits (221), Expect = 1e-18
Identities = 57/181 (31%), Positives = 106/181 (58%), Gaps = 6/181 (3%)
Frame = -2
Query: 674 LDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPE--SLINLKKLEVLNISNNFVQTLP 501
L+L +L +P + L +L++L+L SN ++ + E S +LK+L L + +N + T+P
Sbjct: 283 LELQNCELERIPHAIFSLSNLQELDLKSNNIRTIEEIISFQHLKRLTCLKLWHNKIVTIP 342
Query: 500 VCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVIE-LNL 324
+ ++ NL+ +Y SNNKL++ P + LQ L LD+S+N I+ IP + L ++ L++
Sbjct: 343 PSITHVKNLESLYFSNNKLESLPVAVFSLQKLRCLDVSYNNISMIPIEIGLLQNLQHLHI 402
Query: 323 SQNEISLIGEDLHQAPRLKILRLDENCL-SLDEIKPSLLRDSKIHTVSVDGNLFE--PKQ 153
+ N++ ++ + L + +L+ L L +NC+ SL E L S++ + + GN + P Q
Sbjct: 403 TGNKVDILPKQLFKCIKLRTLNLGQNCITSLPEKVGQL---SQLTQLELKGNCLDRLPAQ 459
Query: 152 L 150
L
Sbjct: 460 L 460
Score = 33.5 bits (73), Expect = 0.81
Identities = 30/121 (24%), Positives = 55/121 (45%), Gaps = 8/121 (6%)
Frame = -2
Query: 584 LQALPESLINLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQS- 408
L +P+++ +L L+VL + +P + + NL++++ + + L+
Sbjct: 122 LSGVPDAVFDLTDLDVLKLELIPEAKIPAKISQMTNLQELHLCHCPAKVEQTAFSFLRDH 181
Query: 407 LDVLDLSHNKITEIPY------GMSELYVIELNLSQNEISLIG-EDLHQAPRLKILRLDE 249
L L + + EIP + ELY+I NL+ +IG E L + LKIL +
Sbjct: 182 LRCLHVKFTDVAEIPAWVYLLKNLRELYLIG-NLNSENNKMIGLESLRELRHLKILHVKS 240
Query: 248 N 246
N
Sbjct: 241 N 241
>AL391497-3|CAH72226.1| 858|Homo sapiens leucine rich repeat
containing 8 family, member D protein.
Length = 858
Score = 96.7 bits (230), Expect = 8e-20
Identities = 67/208 (32%), Positives = 110/208 (52%), Gaps = 3/208 (1%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLS--KLKHLKQLNLDSNKLQALPE 567
+ +C+L+ IP +FSL + L+ LDL N + + + +S LK L L L NK+ +P
Sbjct: 642 LQNCELERIPHAIFSLSN-LQELDLKSNNIRTIEEIISFQHLKRLTCLKLWHNKIVTIPP 700
Query: 566 SLINLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLS 387
S+ ++K LE L SNN +++LPV + +L L+ + S N + P +I LQ+L L ++
Sbjct: 701 SITHVKNLESLYFSNNKLESLPVAVFSLQKLRCLDVSYNNISMIPIEIGLLQNLQHLHIT 760
Query: 386 HNKITEIPYGMSELYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLL 210
NK+ +P + + + LNL QN I+ + E + Q +L L L NCL +
Sbjct: 761 GNKVDILPKQLFKCIKLRTLNLGQNCITSLPEKVGQLSQLTQLELKGNCLDRLPAQLGQC 820
Query: 209 RDSKIHTVSVDGNLFEPKQLAXLEGYNE 126
R K + V+ +LF+ L E N+
Sbjct: 821 RMLKKSGLVVEDHLFDTLPLEVKEALNQ 848
Score = 93.1 bits (221), Expect = 1e-18
Identities = 57/181 (31%), Positives = 106/181 (58%), Gaps = 6/181 (3%)
Frame = -2
Query: 674 LDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPE--SLINLKKLEVLNISNNFVQTLP 501
L+L +L +P + L +L++L+L SN ++ + E S +LK+L L + +N + T+P
Sbjct: 640 LELQNCELERIPHAIFSLSNLQELDLKSNNIRTIEEIISFQHLKRLTCLKLWHNKIVTIP 699
Query: 500 VCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVIE-LNL 324
+ ++ NL+ +Y SNNKL++ P + LQ L LD+S+N I+ IP + L ++ L++
Sbjct: 700 PSITHVKNLESLYFSNNKLESLPVAVFSLQKLRCLDVSYNNISMIPIEIGLLQNLQHLHI 759
Query: 323 SQNEISLIGEDLHQAPRLKILRLDENCL-SLDEIKPSLLRDSKIHTVSVDGNLFE--PKQ 153
+ N++ ++ + L + +L+ L L +NC+ SL E L S++ + + GN + P Q
Sbjct: 760 TGNKVDILPKQLFKCIKLRTLNLGQNCITSLPEKVGQL---SQLTQLELKGNCLDRLPAQ 816
Query: 152 L 150
L
Sbjct: 817 L 817
Score = 33.5 bits (73), Expect = 0.81
Identities = 30/121 (24%), Positives = 55/121 (45%), Gaps = 8/121 (6%)
Frame = -2
Query: 584 LQALPESLINLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQS- 408
L +P+++ +L L+VL + +P + + NL++++ + + L+
Sbjct: 479 LSGVPDAVFDLTDLDVLKLELIPEAKIPAKISQMTNLQELHLCHCPAKVEQTAFSFLRDH 538
Query: 407 LDVLDLSHNKITEIPY------GMSELYVIELNLSQNEISLIG-EDLHQAPRLKILRLDE 249
L L + + EIP + ELY+I NL+ +IG E L + LKIL +
Sbjct: 539 LRCLHVKFTDVAEIPAWVYLLKNLRELYLIG-NLNSENNKMIGLESLRELRHLKILHVKS 597
Query: 248 N 246
N
Sbjct: 598 N 598
>AK001332-1|BAA91631.1| 682|Homo sapiens protein ( Homo sapiens cDNA
FLJ10470 fis, clone NT2RP2000032, weakly similar to RAS
SUPPRESSOR PROTEIN 1. ).
Length = 682
Score = 96.7 bits (230), Expect = 8e-20
Identities = 67/208 (32%), Positives = 110/208 (52%), Gaps = 3/208 (1%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLS--KLKHLKQLNLDSNKLQALPE 567
+ +C+L+ IP +FSL + L+ LDL N + + + +S LK L L L NK+ +P
Sbjct: 466 LQNCELERIPHAIFSLSN-LQELDLKSNNIRTIEEIISFQHLKRLTCLKLWHNKIVTIPP 524
Query: 566 SLINLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLS 387
S+ ++K LE L SNN +++LPV + +L L+ + S N + P +I LQ+L L ++
Sbjct: 525 SITHVKNLESLYFSNNKLESLPVAVFSLQKLRCLDVSYNNISMIPIEIGLLQNLQHLHIT 584
Query: 386 HNKITEIPYGMSELYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLL 210
NK+ +P + + + LNL QN I+ + E + Q +L L L NCL +
Sbjct: 585 GNKVDILPKQLFKCIKLRTLNLGQNCITSLPEKVGQLSQLTQLELKGNCLDRLPAQLGQC 644
Query: 209 RDSKIHTVSVDGNLFEPKQLAXLEGYNE 126
R K + V+ +LF+ L E N+
Sbjct: 645 RMLKKSGLVVEDHLFDTLPLEVKEALNQ 672
Score = 93.1 bits (221), Expect = 1e-18
Identities = 57/181 (31%), Positives = 106/181 (58%), Gaps = 6/181 (3%)
Frame = -2
Query: 674 LDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPE--SLINLKKLEVLNISNNFVQTLP 501
L+L +L +P + L +L++L+L SN ++ + E S +LK+L L + +N + T+P
Sbjct: 464 LELQNCELERIPHAIFSLSNLQELDLKSNNIRTIEEIISFQHLKRLTCLKLWHNKIVTIP 523
Query: 500 VCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVIE-LNL 324
+ ++ NL+ +Y SNNKL++ P + LQ L LD+S+N I+ IP + L ++ L++
Sbjct: 524 PSITHVKNLESLYFSNNKLESLPVAVFSLQKLRCLDVSYNNISMIPIEIGLLQNLQHLHI 583
Query: 323 SQNEISLIGEDLHQAPRLKILRLDENCL-SLDEIKPSLLRDSKIHTVSVDGNLFE--PKQ 153
+ N++ ++ + L + +L+ L L +NC+ SL E L S++ + + GN + P Q
Sbjct: 584 TGNKVDILPKQLFKCIKLRTLNLGQNCITSLPEKVGQL---SQLTQLELKGNCLDRLPAQ 640
Query: 152 L 150
L
Sbjct: 641 L 641
Score = 33.5 bits (73), Expect = 0.81
Identities = 30/121 (24%), Positives = 55/121 (45%), Gaps = 8/121 (6%)
Frame = -2
Query: 584 LQALPESLINLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQS- 408
L +P+++ +L L+VL + +P + + NL++++ + + L+
Sbjct: 303 LSGVPDAVFDLTDLDVLKLELIPEAKIPAKISQMTNLQELHLCHCPAKVEQTAFSFLRDH 362
Query: 407 LDVLDLSHNKITEIPY------GMSELYVIELNLSQNEISLIG-EDLHQAPRLKILRLDE 249
L L + + EIP + ELY+I NL+ +IG E L + LKIL +
Sbjct: 363 LRCLHVKFTDVAEIPAWVYLLKNLRELYLIG-NLNSENNKMIGLESLRELRHLKILHVKS 421
Query: 248 N 246
N
Sbjct: 422 N 422
>AL359880-1|CAH70792.1| 734|Homo sapiens leucine-rich repeats and
calponin homology (CH) domain containing 1 protein.
Length = 734
Score = 96.3 bits (229), Expect = 1e-19
Identities = 62/166 (37%), Positives = 99/166 (59%), Gaps = 4/166 (2%)
Frame = -2
Query: 728 KLKEIPIDV---FSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLI 558
KLKE P L D ++ DLSKN+L +P +L L+ LNL N ++ +PE+++
Sbjct: 82 KLKEFPRTAAPGHDLSDTVQ-ADLSKNRLVEVPMELCHFVSLEILNLYHNCIRVIPEAIV 140
Query: 557 NLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNK 378
NL+ L LN+S N + LP CL L LK + ASNNKL + P++I L+ L LD+S N+
Sbjct: 141 NLQMLTYLNLSRNQLSALPACLCGL-PLKVLIASNNKLGSLPEEIGQLKQLMELDVSCNE 199
Query: 377 ITEIPYGMSELYVI-ELNLSQNEISLIGEDLHQAPRLKILRLDENC 243
IT +P + +L + ELN+ +N + ++ ++L L +++ D +C
Sbjct: 200 ITALPQQIGQLKSLRELNVRRNYLKVLPQELVD---LSLVKFDFSC 242
Score = 80.6 bits (190), Expect = 5e-15
Identities = 52/163 (31%), Positives = 92/163 (56%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
+L E+P+++ L L+L N + V+P+ + L+ L LNL N+L ALP L L
Sbjct: 108 RLVEVPMELCHFVS-LEILNLYHNCIRVIPEAIVNLQMLTYLNLSRNQLSALPACLCGLP 166
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITE 369
L+VL SNN + +LP + L L ++ S N++ A P+QI L+SL L++ N +
Sbjct: 167 -LKVLIASNNKLGSLPEEIGQLKQLMELDVSCNEITALPQQIGQLKSLRELNVRRNYLKV 225
Query: 368 IPYGMSELYVIELNLSQNEISLIGEDLHQAPRLKILRLDENCL 240
+P + +L +++ + S N++ +I + +L++L L+ N L
Sbjct: 226 LPQELVDLSLVKFDFSCNKVLVIPICFREMKQLQVLLLENNPL 268
Score = 67.3 bits (157), Expect = 5e-11
Identities = 34/102 (33%), Positives = 62/102 (60%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
KL +P ++ L ++ LD+S N+++ LP + +LK L++LN+ N L+ LP+ L++L
Sbjct: 176 KLGSLPEEIGQLKQLME-LDVSCNEITALPQQIGQLKSLRELNVRRNYLKVLPQELVDLS 234
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQI 423
++ + S N V +P+C + + L+ + NN LQ+ P QI
Sbjct: 235 LVK-FDFSCNKVLVIPICFREMKQLQVLLLENNPLQSPPAQI 275
Score = 65.3 bits (152), Expect = 2e-10
Identities = 39/112 (34%), Positives = 65/112 (58%), Gaps = 1/112 (0%)
Frame = -2
Query: 695 LCDV-LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNN 519
LC + L+ L S NKL LP+++ +LK L +L++ N++ ALP+ + LK L LN+ N
Sbjct: 162 LCGLPLKVLIASNNKLGSLPEEIGQLKQLMELDVSCNEITALPQQIGQLKSLRELNVRRN 221
Query: 518 FVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIP 363
+++ LP L +L+ +K + S NK+ P ++ L VL L +N + P
Sbjct: 222 YLKVLPQELVDLSLVKFDF-SCNKVLVIPICFREMKQLQVLLLENNPLQSPP 272
Score = 33.1 bits (72), Expect = 1.1
Identities = 20/63 (31%), Positives = 34/63 (53%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKK 546
LK +P ++ L L D S NK+ V+P ++K L+ L L++N LQ+ P + K
Sbjct: 223 LKVLPQELVDLS--LVKFDFSCNKVLVIPICFREMKQLQVLLLENNPLQSPPAQICTKGK 280
Query: 545 LEV 537
+ +
Sbjct: 281 VHI 283
>AL138704-1|CAH73642.1| 734|Homo sapiens leucine-rich repeats and
calponin homology (CH) domain containing 1 protein.
Length = 734
Score = 96.3 bits (229), Expect = 1e-19
Identities = 62/166 (37%), Positives = 99/166 (59%), Gaps = 4/166 (2%)
Frame = -2
Query: 728 KLKEIPIDV---FSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLI 558
KLKE P L D ++ DLSKN+L +P +L L+ LNL N ++ +PE+++
Sbjct: 82 KLKEFPRTAAPGHDLSDTVQ-ADLSKNRLVEVPMELCHFVSLEILNLYHNCIRVIPEAIV 140
Query: 557 NLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNK 378
NL+ L LN+S N + LP CL L LK + ASNNKL + P++I L+ L LD+S N+
Sbjct: 141 NLQMLTYLNLSRNQLSALPACLCGL-PLKVLIASNNKLGSLPEEIGQLKQLMELDVSCNE 199
Query: 377 ITEIPYGMSELYVI-ELNLSQNEISLIGEDLHQAPRLKILRLDENC 243
IT +P + +L + ELN+ +N + ++ ++L L +++ D +C
Sbjct: 200 ITALPQQIGQLKSLRELNVRRNYLKVLPQELVD---LSLVKFDFSC 242
Score = 80.6 bits (190), Expect = 5e-15
Identities = 52/163 (31%), Positives = 92/163 (56%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
+L E+P+++ L L+L N + V+P+ + L+ L LNL N+L ALP L L
Sbjct: 108 RLVEVPMELCHFVS-LEILNLYHNCIRVIPEAIVNLQMLTYLNLSRNQLSALPACLCGLP 166
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITE 369
L+VL SNN + +LP + L L ++ S N++ A P+QI L+SL L++ N +
Sbjct: 167 -LKVLIASNNKLGSLPEEIGQLKQLMELDVSCNEITALPQQIGQLKSLRELNVRRNYLKV 225
Query: 368 IPYGMSELYVIELNLSQNEISLIGEDLHQAPRLKILRLDENCL 240
+P + +L +++ + S N++ +I + +L++L L+ N L
Sbjct: 226 LPQELVDLSLVKFDFSCNKVLVIPICFREMKQLQVLLLENNPL 268
Score = 67.3 bits (157), Expect = 5e-11
Identities = 34/102 (33%), Positives = 62/102 (60%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
KL +P ++ L ++ LD+S N+++ LP + +LK L++LN+ N L+ LP+ L++L
Sbjct: 176 KLGSLPEEIGQLKQLME-LDVSCNEITALPQQIGQLKSLRELNVRRNYLKVLPQELVDLS 234
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQI 423
++ + S N V +P+C + + L+ + NN LQ+ P QI
Sbjct: 235 LVK-FDFSCNKVLVIPICFREMKQLQVLLLENNPLQSPPAQI 275
Score = 65.3 bits (152), Expect = 2e-10
Identities = 39/112 (34%), Positives = 65/112 (58%), Gaps = 1/112 (0%)
Frame = -2
Query: 695 LCDV-LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNN 519
LC + L+ L S NKL LP+++ +LK L +L++ N++ ALP+ + LK L LN+ N
Sbjct: 162 LCGLPLKVLIASNNKLGSLPEEIGQLKQLMELDVSCNEITALPQQIGQLKSLRELNVRRN 221
Query: 518 FVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIP 363
+++ LP L +L+ +K + S NK+ P ++ L VL L +N + P
Sbjct: 222 YLKVLPQELVDLSLVKFDF-SCNKVLVIPICFREMKQLQVLLLENNPLQSPP 272
Score = 33.1 bits (72), Expect = 1.1
Identities = 20/63 (31%), Positives = 34/63 (53%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKK 546
LK +P ++ L L D S NK+ V+P ++K L+ L L++N LQ+ P + K
Sbjct: 223 LKVLPQELVDLS--LVKFDFSCNKVLVIPICFREMKQLQVLLLENNPLQSPPAQICTKGK 280
Query: 545 LEV 537
+ +
Sbjct: 281 VHI 283
>AK222787-1|BAD96507.1| 671|Homo sapiens leucine rich repeat
containing 5 variant protein.
Length = 671
Score = 95.9 bits (228), Expect = 1e-19
Identities = 67/208 (32%), Positives = 109/208 (52%), Gaps = 3/208 (1%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLS--KLKHLKQLNLDSNKLQALPE 567
+ +C+L+ IP +FSL + L+ LDL N + + + +S LK L L L NK+ +P
Sbjct: 455 LQNCELERIPHAIFSLSN-LQELDLKSNNIRTIEEIISFQHLKRLTCLKLWHNKIVTIPP 513
Query: 566 SLINLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLS 387
S+ ++K LE L SNN +++LPV + +L L+ + S N + P +I LQ L L ++
Sbjct: 514 SITHVKNLESLYFSNNKLESLPVAVFSLQKLRCLDVSYNNISMIPIEIGLLQDLQHLHIT 573
Query: 386 HNKITEIPYGMSELYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLL 210
NK+ +P + + + LNL QN I+ + E + Q +L L L NCL +
Sbjct: 574 GNKVDILPKQLFKCIKLRTLNLGQNCITSLPEKVGQLSQLTQLELKGNCLDRLPAQLGQC 633
Query: 209 RDSKIHTVSVDGNLFEPKQLAXLEGYNE 126
R K + V+ +LF+ L E N+
Sbjct: 634 RMLKKSGLVVEDHLFDTLPLEVEEALNQ 661
Score = 93.1 bits (221), Expect = 1e-18
Identities = 57/181 (31%), Positives = 106/181 (58%), Gaps = 6/181 (3%)
Frame = -2
Query: 674 LDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPE--SLINLKKLEVLNISNNFVQTLP 501
L+L +L +P + L +L++L+L SN ++ + E S +LK+L L + +N + T+P
Sbjct: 453 LELQNCELERIPHAIFSLSNLQELDLKSNNIRTIEEIISFQHLKRLTCLKLWHNKIVTIP 512
Query: 500 VCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVIE-LNL 324
+ ++ NL+ +Y SNNKL++ P + LQ L LD+S+N I+ IP + L ++ L++
Sbjct: 513 PSITHVKNLESLYFSNNKLESLPVAVFSLQKLRCLDVSYNNISMIPIEIGLLQDLQHLHI 572
Query: 323 SQNEISLIGEDLHQAPRLKILRLDENCL-SLDEIKPSLLRDSKIHTVSVDGNLFE--PKQ 153
+ N++ ++ + L + +L+ L L +NC+ SL E L S++ + + GN + P Q
Sbjct: 573 TGNKVDILPKQLFKCIKLRTLNLGQNCITSLPEKVGQL---SQLTQLELKGNCLDRLPAQ 629
Query: 152 L 150
L
Sbjct: 630 L 630
Score = 33.5 bits (73), Expect = 0.81
Identities = 30/121 (24%), Positives = 55/121 (45%), Gaps = 8/121 (6%)
Frame = -2
Query: 584 LQALPESLINLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQS- 408
L +P+++ +L L+VL + +P + + NL++++ + + L+
Sbjct: 292 LSGVPDAVFDLTDLDVLKLELIPEAKIPAKISQMTNLQELHLCHCPAKVEQTAFSFLRDH 351
Query: 407 LDVLDLSHNKITEIPY------GMSELYVIELNLSQNEISLIG-EDLHQAPRLKILRLDE 249
L L + + EIP + ELY+I NL+ +IG E L + LKIL +
Sbjct: 352 LRCLHVKFTDVAEIPAWVYLLKNLRELYLIG-NLNSENNKMIGLESLRELRHLKILHVKS 410
Query: 248 N 246
N
Sbjct: 411 N 411
>D63481-1|BAA09768.3| 1630|Homo sapiens KIAA0147 protein protein.
Length = 1630
Score = 95.1 bits (226), Expect = 2e-19
Identities = 58/163 (35%), Positives = 94/163 (57%), Gaps = 1/163 (0%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKK 546
L +P D F+ L +L L+ L LP D+ L +L L L N L++LP SL L K
Sbjct: 117 LSRLP-DGFTQLRSLAHLALNDVSLQALPGDVGNLANLVTLELRENLLKSLPASLSFLVK 175
Query: 545 LEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEI 366
LE L++ N ++ LP L L NL++++ N+L A P ++ L+ L LD+S N++ E+
Sbjct: 176 LEQLDLGGNDLEVLPDTLGALPNLRELWLDRNQLSALPPELGNLRRLVCLDVSENRLEEL 235
Query: 365 PYGMSELYVI-ELNLSQNEISLIGEDLHQAPRLKILRLDENCL 240
P + L ++ +L LSQN + + + + Q +L IL++D+N L
Sbjct: 236 PAELGGLVLLTDLLLSQNLLRRLPDGIGQLKQLSILKVDQNRL 278
Score = 88.2 bits (209), Expect = 3e-17
Identities = 57/163 (34%), Positives = 87/163 (53%), Gaps = 1/163 (0%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKK 546
LK +P + L L LDL N L VLPD L L +L++L LD N+L ALP L NL++
Sbjct: 163 LKSLPASLSFLVK-LEQLDLGGNDLEVLPDTLGALPNLRELWLDRNQLSALPPELGNLRR 221
Query: 545 LEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEI 366
L L++S N ++ LP L L L + S N L+ P I L+ L +L + N++ E+
Sbjct: 222 LVCLDVSENRLEELPAELGGLVLLTDLLLSQNLLRRLPDGIGQLKQLSILKVDQNRLCEV 281
Query: 365 PYGMSEL-YVIELNLSQNEISLIGEDLHQAPRLKILRLDENCL 240
+ + + EL L++N + + L + +L L +D N L
Sbjct: 282 TEAIGDCENLSELILTENLLMALPRSLGKLTKLTNLNVDRNHL 324
Score = 87.4 bits (207), Expect = 5e-17
Identities = 61/199 (30%), Positives = 102/199 (51%), Gaps = 3/199 (1%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
+L+E+P F L + LR L LS N++ LP +++ L +L++ N + +PES+ K
Sbjct: 47 QLRELPKPFFRLLN-LRKLGLSDNEIQRLPPEVANFMQLVELDVSRNDIPEIPESIKFCK 105
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITE 369
LE+ + S N + LP L +L + ++ LQA P + L +L L+L N +
Sbjct: 106 ALEIADFSGNPLSRLPDGFTQLRSLAHLALNDVSLQALPGDVGNLANLVTLELRENLLKS 165
Query: 368 IPYGMSELYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIH 192
+P +S L +E L+L N++ ++ + L P L+ L LD N LS + P L ++
Sbjct: 166 LPASLSFLVKLEQLDLGGNDLEVLPDTLGALPNLRELWLDRNQLS--ALPPELGNLRRLV 223
Query: 191 TVSVDGNLFE--PKQLAXL 141
+ V N E P +L L
Sbjct: 224 CLDVSENRLEELPAELGGL 242
Score = 74.5 bits (175), Expect = 4e-13
Identities = 44/140 (31%), Positives = 80/140 (57%), Gaps = 3/140 (2%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESL 561
+++ +L+E+P ++ L +L +L LS+N L LPD + +LK L L +D N+L + E++
Sbjct: 227 VSENRLEELPAELGGLV-LLTDLLLSQNLLRRLPDGIGQLKQLSILKVDQNRLCEVTEAI 285
Query: 560 INLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHN 381
+ + L L ++ N + LP L L L + N L+A P +I G +L VL L N
Sbjct: 286 GDCENLSELILTENLLMALPRSLGKLTKLTNLNVDRNHLEALPPEIGGCVALSVLSLRDN 345
Query: 380 KITEIPYGM---SELYVIEL 330
++ +P + +EL+V+++
Sbjct: 346 RLAVLPPELAHTTELHVLDV 365
Score = 72.9 bits (171), Expect = 1e-12
Identities = 53/191 (27%), Positives = 96/191 (50%), Gaps = 5/191 (2%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKL-KHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQT 507
+ ++D L +P+++ + + L++L LD+N+L+ LP+ L L L +S+N +Q
Sbjct: 14 VESVDKRHCSLQAVPEEIYRYSRSLEELLLDANQLRELPKPFFRLLNLRKLGLSDNEIQR 73
Query: 506 LPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVIELN 327
LP + N L ++ S N + P+ I ++L++ D S N ++ +P G ++L + +
Sbjct: 74 LPPEVANFMQLVELDVSRNDIPEIPESIKFCKALEIADFSGNPLSRLPDGFTQLRSL-AH 132
Query: 326 LSQNEISL--IGEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIHTVSVDGNLFE--P 159
L+ N++SL + D+ L L L EN L + SL K+ + + GN E P
Sbjct: 133 LALNDVSLQALPGDVGNLANLVTLELRENLLK--SLPASLSFLVKLEQLDLGGNDLEVLP 190
Query: 158 KQLAXLEGYNE 126
L L E
Sbjct: 191 DTLGALPNLRE 201
Score = 66.1 bits (154), Expect = 1e-10
Identities = 40/146 (27%), Positives = 73/146 (50%), Gaps = 1/146 (0%)
Frame = -2
Query: 674 LDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTLPVC 495
LD+S+N+L LP +L L L L L N L+ LP+ + LK+L +L + N + +
Sbjct: 225 LDVSENRLEELPAELGGLVLLTDLLLSQNLLRRLPDGIGQLKQLSILKVDQNRLCEVTEA 284
Query: 494 LKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVIE-LNLSQ 318
+ + NL ++ + N L A P+ + L L L++ N + +P + + L+L
Sbjct: 285 IGDCENLSELILTENLLMALPRSLGKLTKLTNLNVDRNHLEALPPEIGGCVALSVLSLRD 344
Query: 317 NEISLIGEDLHQAPRLKILRLDENCL 240
N ++++ +L L +L + N L
Sbjct: 345 NRLAVLPPELAHTTELHVLDVAGNRL 370
Score = 65.7 bits (153), Expect = 2e-10
Identities = 39/138 (28%), Positives = 72/138 (52%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKK 546
L+ +P + L L L + +N+L + + + ++L +L L N L ALP SL L K
Sbjct: 255 LRRLPDGIGQLKQ-LSILKVDQNRLCEVTEAIGDCENLSELILTENLLMALPRSLGKLTK 313
Query: 545 LEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEI 366
L LN+ N ++ LP + L + +N+L P ++ L VLD++ N++ +
Sbjct: 314 LTNLNVDRNHLEALPPEIGGCVALSVLSLRDNRLAVLPPELAHTTELHVLDVAGNRLQSL 373
Query: 365 PYGMSELYVIELNLSQNE 312
P+ ++ L + L L++N+
Sbjct: 374 PFALTHLNLKALWLAENQ 391
>AY062238-1|AAL38976.1| 1630|Homo sapiens scribble protein.
Length = 1630
Score = 95.1 bits (226), Expect = 2e-19
Identities = 58/163 (35%), Positives = 94/163 (57%), Gaps = 1/163 (0%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKK 546
L +P D F+ L +L L+ L LP D+ L +L L L N L++LP SL L K
Sbjct: 117 LSRLP-DGFTQLRSLAHLALNDVSLQALPGDVGNLANLVTLELRENLLKSLPASLSFLVK 175
Query: 545 LEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEI 366
LE L++ N ++ LP L L NL++++ N+L A P ++ L+ L LD+S N++ E+
Sbjct: 176 LEQLDLGGNDLEVLPDTLGALPNLRELWLDRNQLSALPPELGNLRRLVCLDVSENRLEEL 235
Query: 365 PYGMSELYVI-ELNLSQNEISLIGEDLHQAPRLKILRLDENCL 240
P + L ++ +L LSQN + + + + Q +L IL++D+N L
Sbjct: 236 PAELGGLVLLTDLLLSQNLLRRLPDGIGQLKQLSILKVDQNRL 278
Score = 88.2 bits (209), Expect = 3e-17
Identities = 57/163 (34%), Positives = 87/163 (53%), Gaps = 1/163 (0%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKK 546
LK +P + L L LDL N L VLPD L L +L++L LD N+L ALP L NL++
Sbjct: 163 LKSLPASLSFLVK-LEQLDLGGNDLEVLPDTLGALPNLRELWLDRNQLSALPPELGNLRR 221
Query: 545 LEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEI 366
L L++S N ++ LP L L L + S N L+ P I L+ L +L + N++ E+
Sbjct: 222 LVCLDVSENRLEELPAELGGLVLLTDLLLSQNLLRRLPDGIGQLKQLSILKVDQNRLCEV 281
Query: 365 PYGMSEL-YVIELNLSQNEISLIGEDLHQAPRLKILRLDENCL 240
+ + + EL L++N + + L + +L L +D N L
Sbjct: 282 TEAIGDCENLSELILTENLLMALPRSLGKLTKLTNLNVDRNHL 324
Score = 87.4 bits (207), Expect = 5e-17
Identities = 61/199 (30%), Positives = 102/199 (51%), Gaps = 3/199 (1%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
+L+E+P F L + LR L LS N++ LP +++ L +L++ N + +PES+ K
Sbjct: 47 QLRELPKPFFRLLN-LRKLGLSDNEIQRLPPEVANFMQLVELDVSRNDIPEIPESIKFCK 105
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITE 369
LE+ + S N + LP L +L + ++ LQA P + L +L L+L N +
Sbjct: 106 ALEIADFSGNPLSRLPDGFTQLRSLAHLALNDVSLQALPGDVGNLANLVTLELRENLLKS 165
Query: 368 IPYGMSELYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIH 192
+P +S L +E L+L N++ ++ + L P L+ L LD N LS + P L ++
Sbjct: 166 LPASLSFLVKLEQLDLGGNDLEVLPDTLGALPNLRELWLDRNQLS--ALPPELGNLRRLV 223
Query: 191 TVSVDGNLFE--PKQLAXL 141
+ V N E P +L L
Sbjct: 224 CLDVSENRLEELPAELGGL 242
Score = 74.5 bits (175), Expect = 4e-13
Identities = 44/140 (31%), Positives = 80/140 (57%), Gaps = 3/140 (2%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESL 561
+++ +L+E+P ++ L +L +L LS+N L LPD + +LK L L +D N+L + E++
Sbjct: 227 VSENRLEELPAELGGLV-LLTDLLLSQNLLRRLPDGIGQLKQLSILKVDQNRLCEVTEAI 285
Query: 560 INLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHN 381
+ + L L ++ N + LP L L L + N L+A P +I G +L VL L N
Sbjct: 286 GDCENLSELILTENLLMALPRSLGKLTKLTNLNVDRNHLEALPPEIGGCVALSVLSLRDN 345
Query: 380 KITEIPYGM---SELYVIEL 330
++ +P + +EL+V+++
Sbjct: 346 RLAVLPPELAHTTELHVLDV 365
Score = 72.9 bits (171), Expect = 1e-12
Identities = 53/191 (27%), Positives = 96/191 (50%), Gaps = 5/191 (2%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKL-KHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQT 507
+ ++D L +P+++ + + L++L LD+N+L+ LP+ L L L +S+N +Q
Sbjct: 14 VESVDKRHCSLQAVPEEIYRYSRSLEELLLDANQLRELPKPFFRLLNLRKLGLSDNEIQR 73
Query: 506 LPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVIELN 327
LP + N L ++ S N + P+ I ++L++ D S N ++ +P G ++L + +
Sbjct: 74 LPPEVANFMQLVELDVSRNDIPEIPESIKFCKALEIADFSGNPLSRLPDGFTQLRSL-AH 132
Query: 326 LSQNEISL--IGEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIHTVSVDGNLFE--P 159
L+ N++SL + D+ L L L EN L + SL K+ + + GN E P
Sbjct: 133 LALNDVSLQALPGDVGNLANLVTLELRENLLK--SLPASLSFLVKLEQLDLGGNDLEVLP 190
Query: 158 KQLAXLEGYNE 126
L L E
Sbjct: 191 DTLGALPNLRE 201
Score = 66.1 bits (154), Expect = 1e-10
Identities = 40/146 (27%), Positives = 73/146 (50%), Gaps = 1/146 (0%)
Frame = -2
Query: 674 LDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTLPVC 495
LD+S+N+L LP +L L L L L N L+ LP+ + LK+L +L + N + +
Sbjct: 225 LDVSENRLEELPAELGGLVLLTDLLLSQNLLRRLPDGIGQLKQLSILKVDQNRLCEVTEA 284
Query: 494 LKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVIE-LNLSQ 318
+ + NL ++ + N L A P+ + L L L++ N + +P + + L+L
Sbjct: 285 IGDCENLSELILTENLLMALPRSLGKLTKLTNLNVDRNHLEALPPEIGGCVALSVLSLRD 344
Query: 317 NEISLIGEDLHQAPRLKILRLDENCL 240
N ++++ +L L +L + N L
Sbjct: 345 NRLAVLPPELAHTTELHVLDVAGNRL 370
Score = 65.7 bits (153), Expect = 2e-10
Identities = 39/138 (28%), Positives = 72/138 (52%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKK 546
L+ +P + L L L + +N+L + + + ++L +L L N L ALP SL L K
Sbjct: 255 LRRLPDGIGQLKQ-LSILKVDQNRLCEVTEAIGDCENLSELILTENLLMALPRSLGKLTK 313
Query: 545 LEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEI 366
L LN+ N ++ LP + L + +N+L P ++ L VLD++ N++ +
Sbjct: 314 LTNLNVDRNHLEALPPEIGGCVALSVLSLRDNRLAVLPPELAHTTELHVLDVAGNRLQSL 373
Query: 365 PYGMSELYVIELNLSQNE 312
P+ ++ L + L L++N+
Sbjct: 374 PFALTHLNLKALWLAENQ 391
>AF271734-1|AAP88018.1| 1601|Homo sapiens SCRIB1 variant N1 protein.
Length = 1601
Score = 95.1 bits (226), Expect = 2e-19
Identities = 58/163 (35%), Positives = 94/163 (57%), Gaps = 1/163 (0%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKK 546
L +P D F+ L +L L+ L LP D+ L +L L L N L++LP SL L K
Sbjct: 88 LSRLP-DGFTQLRSLAHLALNDVSLQALPGDVGNLANLVTLELRENLLKSLPASLSFLVK 146
Query: 545 LEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEI 366
LE L++ N ++ LP L L NL++++ N+L A P ++ L+ L LD+S N++ E+
Sbjct: 147 LEQLDLGGNDLEVLPDTLGALPNLRELWLDRNQLSALPPELGNLRRLVCLDVSENRLEEL 206
Query: 365 PYGMSELYVI-ELNLSQNEISLIGEDLHQAPRLKILRLDENCL 240
P + L ++ +L LSQN + + + + Q +L IL++D+N L
Sbjct: 207 PAELGGLVLLTDLLLSQNLLRRLPDGIGQLKQLSILKVDQNRL 249
Score = 88.2 bits (209), Expect = 3e-17
Identities = 57/163 (34%), Positives = 87/163 (53%), Gaps = 1/163 (0%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKK 546
LK +P + L L LDL N L VLPD L L +L++L LD N+L ALP L NL++
Sbjct: 134 LKSLPASLSFLVK-LEQLDLGGNDLEVLPDTLGALPNLRELWLDRNQLSALPPELGNLRR 192
Query: 545 LEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEI 366
L L++S N ++ LP L L L + S N L+ P I L+ L +L + N++ E+
Sbjct: 193 LVCLDVSENRLEELPAELGGLVLLTDLLLSQNLLRRLPDGIGQLKQLSILKVDQNRLCEV 252
Query: 365 PYGMSEL-YVIELNLSQNEISLIGEDLHQAPRLKILRLDENCL 240
+ + + EL L++N + + L + +L L +D N L
Sbjct: 253 TEAIGDCENLSELILTENLLMALPRSLGKLTKLTNLNVDRNHL 295
Score = 81.8 bits (193), Expect = 2e-15
Identities = 56/184 (30%), Positives = 93/184 (50%), Gaps = 3/184 (1%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTL 504
LR L LS N++ LP +++ L +L++ N + +PES+ K LE+ + S N + L
Sbjct: 32 LRKLGLSDNEIQRLPPEVANFMQLVELDVSRNDIPEIPESIKFCKALEIADFSGNPLSRL 91
Query: 503 PVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVIE-LN 327
P L +L + ++ LQA P + L +L L+L N + +P +S L +E L+
Sbjct: 92 PDGFTQLRSLAHLALNDVSLQALPGDVGNLANLVTLELRENLLKSLPASLSFLVKLEQLD 151
Query: 326 LSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIHTVSVDGNLFE--PKQ 153
L N++ ++ + L P L+ L LD N LS + P L ++ + V N E P +
Sbjct: 152 LGGNDLEVLPDTLGALPNLRELWLDRNQLS--ALPPELGNLRRLVCLDVSENRLEELPAE 209
Query: 152 LAXL 141
L L
Sbjct: 210 LGGL 213
Score = 74.5 bits (175), Expect = 4e-13
Identities = 44/140 (31%), Positives = 80/140 (57%), Gaps = 3/140 (2%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESL 561
+++ +L+E+P ++ L +L +L LS+N L LPD + +LK L L +D N+L + E++
Sbjct: 198 VSENRLEELPAELGGLV-LLTDLLLSQNLLRRLPDGIGQLKQLSILKVDQNRLCEVTEAI 256
Query: 560 INLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHN 381
+ + L L ++ N + LP L L L + N L+A P +I G +L VL L N
Sbjct: 257 GDCENLSELILTENLLMALPRSLGKLTKLTNLNVDRNHLEALPPEIGGCVALSVLSLRDN 316
Query: 380 KITEIPYGM---SELYVIEL 330
++ +P + +EL+V+++
Sbjct: 317 RLAVLPPELAHTTELHVLDV 336
Score = 66.1 bits (154), Expect = 1e-10
Identities = 40/146 (27%), Positives = 73/146 (50%), Gaps = 1/146 (0%)
Frame = -2
Query: 674 LDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTLPVC 495
LD+S+N+L LP +L L L L L N L+ LP+ + LK+L +L + N + +
Sbjct: 196 LDVSENRLEELPAELGGLVLLTDLLLSQNLLRRLPDGIGQLKQLSILKVDQNRLCEVTEA 255
Query: 494 LKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVIE-LNLSQ 318
+ + NL ++ + N L A P+ + L L L++ N + +P + + L+L
Sbjct: 256 IGDCENLSELILTENLLMALPRSLGKLTKLTNLNVDRNHLEALPPEIGGCVALSVLSLRD 315
Query: 317 NEISLIGEDLHQAPRLKILRLDENCL 240
N ++++ +L L +L + N L
Sbjct: 316 NRLAVLPPELAHTTELHVLDVAGNRL 341
Score = 65.7 bits (153), Expect = 2e-10
Identities = 39/138 (28%), Positives = 72/138 (52%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKK 546
L+ +P + L L L + +N+L + + + ++L +L L N L ALP SL L K
Sbjct: 226 LRRLPDGIGQLKQ-LSILKVDQNRLCEVTEAIGDCENLSELILTENLLMALPRSLGKLTK 284
Query: 545 LEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEI 366
L LN+ N ++ LP + L + +N+L P ++ L VLD++ N++ +
Sbjct: 285 LTNLNVDRNHLEALPPEIGGCVALSVLSLRDNRLAVLPPELAHTTELHVLDVAGNRLQSL 344
Query: 365 PYGMSELYVIELNLSQNE 312
P+ ++ L + L L++N+
Sbjct: 345 PFALTHLNLKALWLAENQ 362
Score = 41.1 bits (92), Expect = 0.004
Identities = 33/118 (27%), Positives = 58/118 (49%), Gaps = 3/118 (2%)
Frame = -2
Query: 485 LNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVIEL-NLSQNEI 309
L NL+++ S+N++Q P ++ L LD+S N I EIP + +E+ + S N +
Sbjct: 29 LLNLRKLGLSDNEIQRLPPEVANFMQLVELDVSRNDIPEIPESIKFCKALEIADFSGNPL 88
Query: 308 SLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIHTVSVDGNLFE--PKQLAXL 141
S + + Q L L L N +SL + + + + T+ + NL + P L+ L
Sbjct: 89 SRLPDGFTQLRSLAHLAL--NDVSLQALPGDVGNLANLVTLELRENLLKSLPASLSFL 144
>AF240677-1|AAP88017.1| 1630|Homo sapiens CRIB1 protein.
Length = 1630
Score = 95.1 bits (226), Expect = 2e-19
Identities = 58/163 (35%), Positives = 94/163 (57%), Gaps = 1/163 (0%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKK 546
L +P D F+ L +L L+ L LP D+ L +L L L N L++LP SL L K
Sbjct: 117 LSRLP-DGFTQLRSLAHLALNDVSLQALPGDVGNLANLVTLELRENLLKSLPASLSFLVK 175
Query: 545 LEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEI 366
LE L++ N ++ LP L L NL++++ N+L A P ++ L+ L LD+S N++ E+
Sbjct: 176 LEQLDLGGNDLEVLPDTLGALPNLRELWLDRNQLSALPPELGNLRRLVCLDVSENRLEEL 235
Query: 365 PYGMSELYVI-ELNLSQNEISLIGEDLHQAPRLKILRLDENCL 240
P + L ++ +L LSQN + + + + Q +L IL++D+N L
Sbjct: 236 PAELGGLVLLTDLLLSQNLLRRLPDGIGQLKQLSILKVDQNRL 278
Score = 88.2 bits (209), Expect = 3e-17
Identities = 57/163 (34%), Positives = 87/163 (53%), Gaps = 1/163 (0%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKK 546
LK +P + L L LDL N L VLPD L L +L++L LD N+L ALP L NL++
Sbjct: 163 LKSLPASLSFLVK-LEQLDLGGNDLEVLPDTLGALPNLRELWLDRNQLSALPPELGNLRR 221
Query: 545 LEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEI 366
L L++S N ++ LP L L L + S N L+ P I L+ L +L + N++ E+
Sbjct: 222 LVCLDVSENRLEELPAELGGLVLLTDLLLSQNLLRRLPDGIGQLKQLSILKVDQNRLCEV 281
Query: 365 PYGMSEL-YVIELNLSQNEISLIGEDLHQAPRLKILRLDENCL 240
+ + + EL L++N + + L + +L L +D N L
Sbjct: 282 TEAIGDCENLSELILTENLLMALPRSLGKLTKLTNLNVDRNHL 324
Score = 87.4 bits (207), Expect = 5e-17
Identities = 61/199 (30%), Positives = 102/199 (51%), Gaps = 3/199 (1%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
+L+E+P F L + LR L LS N++ LP +++ L +L++ N + +PES+ K
Sbjct: 47 QLRELPKPFFRLLN-LRKLGLSDNEIQRLPPEVANFMQLVELDVSRNDIPEIPESIKFCK 105
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITE 369
LE+ + S N + LP L +L + ++ LQA P + L +L L+L N +
Sbjct: 106 ALEIADFSGNPLSRLPDGFTQLRSLAHLALNDVSLQALPGDVGNLANLVTLELRENLLKS 165
Query: 368 IPYGMSELYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIH 192
+P +S L +E L+L N++ ++ + L P L+ L LD N LS + P L ++
Sbjct: 166 LPASLSFLVKLEQLDLGGNDLEVLPDTLGALPNLRELWLDRNQLS--ALPPELGNLRRLV 223
Query: 191 TVSVDGNLFE--PKQLAXL 141
+ V N E P +L L
Sbjct: 224 CLDVSENRLEELPAELGGL 242
Score = 74.5 bits (175), Expect = 4e-13
Identities = 44/140 (31%), Positives = 80/140 (57%), Gaps = 3/140 (2%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESL 561
+++ +L+E+P ++ L +L +L LS+N L LPD + +LK L L +D N+L + E++
Sbjct: 227 VSENRLEELPAELGGLV-LLTDLLLSQNLLRRLPDGIGQLKQLSILKVDQNRLCEVTEAI 285
Query: 560 INLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHN 381
+ + L L ++ N + LP L L L + N L+A P +I G +L VL L N
Sbjct: 286 GDCENLSELILTENLLMALPRSLGKLTKLTNLNVDRNHLEALPPEIGGCVALSVLSLRDN 345
Query: 380 KITEIPYGM---SELYVIEL 330
++ +P + +EL+V+++
Sbjct: 346 RLAVLPPELAHTTELHVLDV 365
Score = 72.9 bits (171), Expect = 1e-12
Identities = 53/191 (27%), Positives = 96/191 (50%), Gaps = 5/191 (2%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKL-KHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQT 507
+ ++D L +P+++ + + L++L LD+N+L+ LP+ L L L +S+N +Q
Sbjct: 14 VESVDKRHCSLQAVPEEIYRYSRSLEELLLDANQLRELPKPFFRLLNLRKLGLSDNEIQR 73
Query: 506 LPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVIELN 327
LP + N L ++ S N + P+ I ++L++ D S N ++ +P G ++L + +
Sbjct: 74 LPPEVANFMQLVELDVSRNDIPEIPESIKFCKALEIADFSGNPLSRLPDGFTQLRSL-AH 132
Query: 326 LSQNEISL--IGEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIHTVSVDGNLFE--P 159
L+ N++SL + D+ L L L EN L + SL K+ + + GN E P
Sbjct: 133 LALNDVSLQALPGDVGNLANLVTLELRENLLK--SLPASLSFLVKLEQLDLGGNDLEVLP 190
Query: 158 KQLAXLEGYNE 126
L L E
Sbjct: 191 DTLGALPNLRE 201
Score = 66.1 bits (154), Expect = 1e-10
Identities = 40/146 (27%), Positives = 73/146 (50%), Gaps = 1/146 (0%)
Frame = -2
Query: 674 LDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTLPVC 495
LD+S+N+L LP +L L L L L N L+ LP+ + LK+L +L + N + +
Sbjct: 225 LDVSENRLEELPAELGGLVLLTDLLLSQNLLRRLPDGIGQLKQLSILKVDQNRLCEVTEA 284
Query: 494 LKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVIE-LNLSQ 318
+ + NL ++ + N L A P+ + L L L++ N + +P + + L+L
Sbjct: 285 IGDCENLSELILTENLLMALPRSLGKLTKLTNLNVDRNHLEALPPEIGGCVALSVLSLRD 344
Query: 317 NEISLIGEDLHQAPRLKILRLDENCL 240
N ++++ +L L +L + N L
Sbjct: 345 NRLAVLPPELAHTTELHVLDVAGNRL 370
Score = 65.7 bits (153), Expect = 2e-10
Identities = 39/138 (28%), Positives = 72/138 (52%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKK 546
L+ +P + L L L + +N+L + + + ++L +L L N L ALP SL L K
Sbjct: 255 LRRLPDGIGQLKQ-LSILKVDQNRLCEVTEAIGDCENLSELILTENLLMALPRSLGKLTK 313
Query: 545 LEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEI 366
L LN+ N ++ LP + L + +N+L P ++ L VLD++ N++ +
Sbjct: 314 LTNLNVDRNHLEALPPEIGGCVALSVLSLRDNRLAVLPPELAHTTELHVLDVAGNRLQSL 373
Query: 365 PYGMSELYVIELNLSQNE 312
P+ ++ L + L L++N+
Sbjct: 374 PFALTHLNLKALWLAENQ 391
>BC003193-1|AAH03193.1| 524|Homo sapiens leucine rich repeat
containing 1 protein.
Length = 524
Score = 94.3 bits (224), Expect = 4e-19
Identities = 62/191 (32%), Positives = 109/191 (57%), Gaps = 1/191 (0%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESL 561
+ D L+ +P ++ +L + L +L+L +N L+ LPD L++L+ L++L+L +N++ LPES+
Sbjct: 135 VNDISLQSLPENIGNLYN-LASLELRENLLTYLPDSLTQLRRLEELDLGNNEIYNLPESI 193
Query: 560 INLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHN 381
L L+ L + N + LP + NL NL + S N+L+ P++I GL SL L +S N
Sbjct: 194 GALLHLKDLWLDGNQLSELPQEIGNLKNLLCLDVSENRLERLPEEISGLTSLTDLVISQN 253
Query: 380 KITEIPYGMSELYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRD 204
+ IP G+ +L + L + QN ++ + E + + L L L EN L + S+ +
Sbjct: 254 LLETIPDGIGKLKKLSILKVDQNRLTQLPEAVGECESLTELVLTEN--QLLTLPKSIGKL 311
Query: 203 SKIHTVSVDGN 171
K+ ++ D N
Sbjct: 312 KKLSNLNADRN 322
Score = 92.3 bits (219), Expect = 2e-18
Identities = 50/149 (33%), Positives = 83/149 (55%), Gaps = 1/149 (0%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTL 504
L LDL N++ LP+ + L HLK L LD N+L LP+ + NLK L L++S N ++ L
Sbjct: 176 LEELDLGNNEIYNLPESIGALLHLKDLWLDGNQLSELPQEIGNLKNLLCLDVSENRLERL 235
Query: 503 PVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSEL-YVIELN 327
P + L +L + S N L+ P I L+ L +L + N++T++P + E + EL
Sbjct: 236 PEEISGLTSLTDLVISQNLLETIPDGIGKLKKLSILKVDQNRLTQLPEAVGECESLTELV 295
Query: 326 LSQNEISLIGEDLHQAPRLKILRLDENCL 240
L++N++ + + + + +L L D N L
Sbjct: 296 LTENQLLTLPKSIGKLKKLSNLNADRNKL 324
Score = 90.2 bits (214), Expect = 7e-18
Identities = 54/153 (35%), Positives = 93/153 (60%), Gaps = 4/153 (2%)
Frame = -2
Query: 683 LRNLD-LSKNKLSV--LPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFV 513
L+NL LS N +S+ LP+++ L +L L L N L LP+SL L++LE L++ NN +
Sbjct: 127 LQNLTCLSVNDISLQSLPENIGNLYNLASLELRENLLTYLPDSLTQLRRLEELDLGNNEI 186
Query: 512 QTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSEL-YVI 336
LP + L +LK ++ N+L P++I L++L LD+S N++ +P +S L +
Sbjct: 187 YNLPESIGALLHLKDLWLDGNQLSELPQEIGNLKNLLCLDVSENRLERLPEEISGLTSLT 246
Query: 335 ELNLSQNEISLIGEDLHQAPRLKILRLDENCLS 237
+L +SQN + I + + + +L IL++D+N L+
Sbjct: 247 DLVISQNLLETIPDGIGKLKKLSILKVDQNRLT 279
Score = 84.6 bits (200), Expect = 3e-16
Identities = 54/166 (32%), Positives = 92/166 (55%), Gaps = 1/166 (0%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESL 561
+++ +L+ +P ++ L L +L +S+N L +PD + KLK L L +D N+L LPE++
Sbjct: 227 VSENRLERLPEEISGLTS-LTDLVISQNLLETIPDGIGKLKKLSILKVDQNRLTQLPEAV 285
Query: 560 INLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHN 381
+ L L ++ N + TLP + L L + A NKL + PK+I G SL V + N
Sbjct: 286 GECESLTELVLTENQLLTLPKSIGKLKKLSNLNADRNKLVSLPKEIGGCCSLTVFCVRDN 345
Query: 380 KITEIPYGMSELYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDEN 246
++T IP +S+ + L+++ N + + L A +LK L L +N
Sbjct: 346 RLTRIPAEVSQATELHVLDVAGNRLLHLPLSL-TALKLKALWLSDN 390
Score = 82.6 bits (195), Expect = 1e-15
Identities = 55/187 (29%), Positives = 99/187 (52%), Gaps = 1/187 (0%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
++ EIP + S C L+ D S N L+ LP+ +L++L L+++ LQ+LPE++ NL
Sbjct: 93 EIPEIPESI-SFCKALQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLPENIGNLY 151
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITE 369
L L + N + LP L L L+++ NN++ P+ I L L L L N+++E
Sbjct: 152 NLASLELRENLLTYLPDSLTQLRRLEELDLGNNEIYNLPESIGALLHLKDLWLDGNQLSE 211
Query: 368 IPYGMSEL-YVIELNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIH 192
+P + L ++ L++S+N + + E++ L L + +N L+ I + + K+
Sbjct: 212 LPQEIGNLKNLLCLDVSENRLERLPEEISGLTSLTDLVISQNL--LETIPDGIGKLKKLS 269
Query: 191 TVSVDGN 171
+ VD N
Sbjct: 270 ILKVDQN 276
Score = 80.6 bits (190), Expect = 5e-15
Identities = 47/168 (27%), Positives = 93/168 (55%), Gaps = 1/168 (0%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESL 561
++D +++ +P ++ + ++ LD+S+N++ +P+ +S K L+ + N L LPES
Sbjct: 66 LSDNEIQRLPPEIANFMQLVE-LDVSRNEIPEIPESISFCKALQVADFSGNPLTRLPESF 124
Query: 560 INLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHN 381
L+ L L++++ +Q+LP + NL NL + N L P + L+ L+ LDL +N
Sbjct: 125 PELQNLTCLSVNDISLQSLPENIGNLYNLASLELRENLLTYLPDSLTQLRRLEELDLGNN 184
Query: 380 KITEIPYGMSE-LYVIELNLSQNEISLIGEDLHQAPRLKILRLDENCL 240
+I +P + L++ +L L N++S + +++ L L + EN L
Sbjct: 185 EIYNLPESIGALLHLKDLWLDGNQLSELPQEIGNLKNLLCLDVSENRL 232
Score = 78.6 bits (185), Expect = 2e-14
Identities = 47/164 (28%), Positives = 88/164 (53%), Gaps = 1/164 (0%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
+L E+P ++ +L ++L LD+S+N+L LP+++S L L L + N L+ +P+ + LK
Sbjct: 208 QLSELPQEIGNLKNLLC-LDVSENRLERLPEEISGLTSLTDLVISQNLLETIPDGIGKLK 266
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITE 369
KL +L + N + LP + +L ++ + N+L PK I L+ L L+ NK+
Sbjct: 267 KLSILKVDQNRLTQLPEAVGECESLTELVLTENQLLTLPKSIGKLKKLSNLNADRNKLVS 326
Query: 368 IPYGMSELYVIEL-NLSQNEISLIGEDLHQAPRLKILRLDENCL 240
+P + + + + N ++ I ++ QA L +L + N L
Sbjct: 327 LPKEIGGCCSLTVFCVRDNRLTRIPAEVSQATELHVLDVAGNRL 370
Score = 77.8 bits (183), Expect = 4e-14
Identities = 55/202 (27%), Positives = 97/202 (48%), Gaps = 4/202 (1%)
Frame = -2
Query: 731 CKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINL 552
C L +P +++ L L L N+L LP+ +L L++L L N++Q LP + N
Sbjct: 22 CSLVYVPEEIYRYARSLEELLLDANQLRELPEQFFQLVKLRKLGLSDNEIQRLPPEIANF 81
Query: 551 KKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKIT 372
+L L++S N + +P + L+ S N L P+ LQ+L L ++ +
Sbjct: 82 MQLVELDVSRNEIPEIPESISFCKALQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQ 141
Query: 371 EIPYGMSELY-VIELNLSQNEISLIGEDLHQAPRLKILRLDEN-CLSLDEIKPSLLRDSK 198
+P + LY + L L +N ++ + + L Q RL+ L L N +L E +LL
Sbjct: 142 SLPENIGNLYNLASLELRENLLTYLPDSLTQLRRLEELDLGNNEIYNLPESIGALLH--- 198
Query: 197 IHTVSVDGNLFE--PKQLAXLE 138
+ + +DGN P+++ L+
Sbjct: 199 LKDLWLDGNQLSELPQEIGNLK 220
Score = 66.1 bits (154), Expect = 1e-10
Identities = 42/138 (30%), Positives = 73/138 (52%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKK 546
L+ IP + L L L + +N+L+ LP+ + + + L +L L N+L LP+S+ LKK
Sbjct: 255 LETIPDGIGKL-KKLSILKVDQNRLTQLPEAVGECESLTELVLTENQLLTLPKSIGKLKK 313
Query: 545 LEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEI 366
L LN N + +LP + +L +N+L P ++ L VLD++ N++ +
Sbjct: 314 LSNLNADRNKLVSLPKEIGGCCSLTVFCVRDNRLTRIPAEVSQATELHVLDVAGNRLLHL 373
Query: 365 PYGMSELYVIELNLSQNE 312
P ++ L + L LS N+
Sbjct: 374 PLSLTALKLKALWLSDNQ 391
>AL513211-1|CAI17358.1| 524|Homo sapiens leucine rich repeat
containing 1 protein.
Length = 524
Score = 94.3 bits (224), Expect = 4e-19
Identities = 62/191 (32%), Positives = 109/191 (57%), Gaps = 1/191 (0%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESL 561
+ D L+ +P ++ +L + L +L+L +N L+ LPD L++L+ L++L+L +N++ LPES+
Sbjct: 135 VNDISLQSLPENIGNLYN-LASLELRENLLTYLPDSLTQLRRLEELDLGNNEIYNLPESI 193
Query: 560 INLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHN 381
L L+ L + N + LP + NL NL + S N+L+ P++I GL SL L +S N
Sbjct: 194 GALLHLKDLWLDGNQLSELPQEIGNLKNLLCLDVSENRLERLPEEISGLTSLTDLVISQN 253
Query: 380 KITEIPYGMSELYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRD 204
+ IP G+ +L + L + QN ++ + E + + L L L EN L + S+ +
Sbjct: 254 LLETIPDGIGKLKKLSILKVDQNRLTQLPEAVGECESLTELVLTEN--QLLTLPKSIGKL 311
Query: 203 SKIHTVSVDGN 171
K+ ++ D N
Sbjct: 312 KKLSNLNADRN 322
Score = 92.3 bits (219), Expect = 2e-18
Identities = 50/149 (33%), Positives = 83/149 (55%), Gaps = 1/149 (0%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTL 504
L LDL N++ LP+ + L HLK L LD N+L LP+ + NLK L L++S N ++ L
Sbjct: 176 LEELDLGNNEIYNLPESIGALLHLKDLWLDGNQLSELPQEIGNLKNLLCLDVSENRLERL 235
Query: 503 PVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSEL-YVIELN 327
P + L +L + S N L+ P I L+ L +L + N++T++P + E + EL
Sbjct: 236 PEEISGLTSLTDLVISQNLLETIPDGIGKLKKLSILKVDQNRLTQLPEAVGECESLTELV 295
Query: 326 LSQNEISLIGEDLHQAPRLKILRLDENCL 240
L++N++ + + + + +L L D N L
Sbjct: 296 LTENQLLTLPKSIGKLKKLSNLNADRNKL 324
Score = 90.2 bits (214), Expect = 7e-18
Identities = 54/153 (35%), Positives = 93/153 (60%), Gaps = 4/153 (2%)
Frame = -2
Query: 683 LRNLD-LSKNKLSV--LPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFV 513
L+NL LS N +S+ LP+++ L +L L L N L LP+SL L++LE L++ NN +
Sbjct: 127 LQNLTCLSVNDISLQSLPENIGNLYNLASLELRENLLTYLPDSLTQLRRLEELDLGNNEI 186
Query: 512 QTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSEL-YVI 336
LP + L +LK ++ N+L P++I L++L LD+S N++ +P +S L +
Sbjct: 187 YNLPESIGALLHLKDLWLDGNQLSELPQEIGNLKNLLCLDVSENRLERLPEEISGLTSLT 246
Query: 335 ELNLSQNEISLIGEDLHQAPRLKILRLDENCLS 237
+L +SQN + I + + + +L IL++D+N L+
Sbjct: 247 DLVISQNLLETIPDGIGKLKKLSILKVDQNRLT 279
Score = 84.6 bits (200), Expect = 3e-16
Identities = 54/166 (32%), Positives = 92/166 (55%), Gaps = 1/166 (0%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESL 561
+++ +L+ +P ++ L L +L +S+N L +PD + KLK L L +D N+L LPE++
Sbjct: 227 VSENRLERLPEEISGLTS-LTDLVISQNLLETIPDGIGKLKKLSILKVDQNRLTQLPEAV 285
Query: 560 INLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHN 381
+ L L ++ N + TLP + L L + A NKL + PK+I G SL V + N
Sbjct: 286 GECESLTELVLTENQLLTLPKSIGKLKKLSNLNADRNKLVSLPKEIGGCCSLTVFCVRDN 345
Query: 380 KITEIPYGMSELYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDEN 246
++T IP +S+ + L+++ N + + L A +LK L L +N
Sbjct: 346 RLTRIPAEVSQATELHVLDVAGNRLLHLPLSL-TALKLKALWLSDN 390
Score = 82.6 bits (195), Expect = 1e-15
Identities = 55/187 (29%), Positives = 99/187 (52%), Gaps = 1/187 (0%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
++ EIP + S C L+ D S N L+ LP+ +L++L L+++ LQ+LPE++ NL
Sbjct: 93 EIPEIPESI-SFCKALQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLPENIGNLY 151
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITE 369
L L + N + LP L L L+++ NN++ P+ I L L L L N+++E
Sbjct: 152 NLASLELRENLLTYLPDSLTQLRRLEELDLGNNEIYNLPESIGALLHLKDLWLDGNQLSE 211
Query: 368 IPYGMSEL-YVIELNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIH 192
+P + L ++ L++S+N + + E++ L L + +N L+ I + + K+
Sbjct: 212 LPQEIGNLKNLLCLDVSENRLERLPEEISGLTSLTDLVISQNL--LETIPDGIGKLKKLS 269
Query: 191 TVSVDGN 171
+ VD N
Sbjct: 270 ILKVDQN 276
Score = 80.6 bits (190), Expect = 5e-15
Identities = 47/168 (27%), Positives = 93/168 (55%), Gaps = 1/168 (0%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESL 561
++D +++ +P ++ + ++ LD+S+N++ +P+ +S K L+ + N L LPES
Sbjct: 66 LSDNEIQRLPPEIANFMQLVE-LDVSRNEIPEIPESISFCKALQVADFSGNPLTRLPESF 124
Query: 560 INLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHN 381
L+ L L++++ +Q+LP + NL NL + N L P + L+ L+ LDL +N
Sbjct: 125 PELQNLTCLSVNDISLQSLPENIGNLYNLASLELRENLLTYLPDSLTQLRRLEELDLGNN 184
Query: 380 KITEIPYGMSE-LYVIELNLSQNEISLIGEDLHQAPRLKILRLDENCL 240
+I +P + L++ +L L N++S + +++ L L + EN L
Sbjct: 185 EIYNLPESIGALLHLKDLWLDGNQLSELPQEIGNLKNLLCLDVSENRL 232
Score = 78.6 bits (185), Expect = 2e-14
Identities = 47/164 (28%), Positives = 88/164 (53%), Gaps = 1/164 (0%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
+L E+P ++ +L ++L LD+S+N+L LP+++S L L L + N L+ +P+ + LK
Sbjct: 208 QLSELPQEIGNLKNLLC-LDVSENRLERLPEEISGLTSLTDLVISQNLLETIPDGIGKLK 266
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITE 369
KL +L + N + LP + +L ++ + N+L PK I L+ L L+ NK+
Sbjct: 267 KLSILKVDQNRLTQLPEAVGECESLTELVLTENQLLTLPKSIGKLKKLSNLNADRNKLVS 326
Query: 368 IPYGMSELYVIEL-NLSQNEISLIGEDLHQAPRLKILRLDENCL 240
+P + + + + N ++ I ++ QA L +L + N L
Sbjct: 327 LPKEIGGCCSLTVFCVRDNRLTRIPAEVSQATELHVLDVAGNRL 370
Score = 77.8 bits (183), Expect = 4e-14
Identities = 55/202 (27%), Positives = 97/202 (48%), Gaps = 4/202 (1%)
Frame = -2
Query: 731 CKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINL 552
C L +P +++ L L L N+L LP+ +L L++L L N++Q LP + N
Sbjct: 22 CSLVYVPEEIYRYARSLEELLLDANQLRELPEQFFQLVKLRKLGLSDNEIQRLPPEIANF 81
Query: 551 KKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKIT 372
+L L++S N + +P + L+ S N L P+ LQ+L L ++ +
Sbjct: 82 MQLVELDVSRNEIPEIPESISFCKALQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQ 141
Query: 371 EIPYGMSELY-VIELNLSQNEISLIGEDLHQAPRLKILRLDEN-CLSLDEIKPSLLRDSK 198
+P + LY + L L +N ++ + + L Q RL+ L L N +L E +LL
Sbjct: 142 SLPENIGNLYNLASLELRENLLTYLPDSLTQLRRLEELDLGNNEIYNLPESIGALLH--- 198
Query: 197 IHTVSVDGNLFE--PKQLAXLE 138
+ + +DGN P+++ L+
Sbjct: 199 LKDLWLDGNQLSELPQEIGNLK 220
Score = 66.1 bits (154), Expect = 1e-10
Identities = 42/138 (30%), Positives = 73/138 (52%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKK 546
L+ IP + L L L + +N+L+ LP+ + + + L +L L N+L LP+S+ LKK
Sbjct: 255 LETIPDGIGKL-KKLSILKVDQNRLTQLPEAVGECESLTELVLTENQLLTLPKSIGKLKK 313
Query: 545 LEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEI 366
L LN N + +LP + +L +N+L P ++ L VLD++ N++ +
Sbjct: 314 LSNLNADRNKLVSLPKEIGGCCSLTVFCVRDNRLTRIPAEVSQATELHVLDVAGNRLLHL 373
Query: 365 PYGMSELYVIELNLSQNE 312
P ++ L + L LS N+
Sbjct: 374 PLSLTALKLKALWLSDNQ 391
>AL033384-1|CAI21666.1| 524|Homo sapiens leucine rich repeat
containing 1 protein.
Length = 524
Score = 94.3 bits (224), Expect = 4e-19
Identities = 62/191 (32%), Positives = 109/191 (57%), Gaps = 1/191 (0%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESL 561
+ D L+ +P ++ +L + L +L+L +N L+ LPD L++L+ L++L+L +N++ LPES+
Sbjct: 135 VNDISLQSLPENIGNLYN-LASLELRENLLTYLPDSLTQLRRLEELDLGNNEIYNLPESI 193
Query: 560 INLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHN 381
L L+ L + N + LP + NL NL + S N+L+ P++I GL SL L +S N
Sbjct: 194 GALLHLKDLWLDGNQLSELPQEIGNLKNLLCLDVSENRLERLPEEISGLTSLTDLVISQN 253
Query: 380 KITEIPYGMSELYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRD 204
+ IP G+ +L + L + QN ++ + E + + L L L EN L + S+ +
Sbjct: 254 LLETIPDGIGKLKKLSILKVDQNRLTQLPEAVGECESLTELVLTEN--QLLTLPKSIGKL 311
Query: 203 SKIHTVSVDGN 171
K+ ++ D N
Sbjct: 312 KKLSNLNADRN 322
Score = 92.3 bits (219), Expect = 2e-18
Identities = 50/149 (33%), Positives = 83/149 (55%), Gaps = 1/149 (0%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTL 504
L LDL N++ LP+ + L HLK L LD N+L LP+ + NLK L L++S N ++ L
Sbjct: 176 LEELDLGNNEIYNLPESIGALLHLKDLWLDGNQLSELPQEIGNLKNLLCLDVSENRLERL 235
Query: 503 PVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSEL-YVIELN 327
P + L +L + S N L+ P I L+ L +L + N++T++P + E + EL
Sbjct: 236 PEEISGLTSLTDLVISQNLLETIPDGIGKLKKLSILKVDQNRLTQLPEAVGECESLTELV 295
Query: 326 LSQNEISLIGEDLHQAPRLKILRLDENCL 240
L++N++ + + + + +L L D N L
Sbjct: 296 LTENQLLTLPKSIGKLKKLSNLNADRNKL 324
Score = 90.2 bits (214), Expect = 7e-18
Identities = 54/153 (35%), Positives = 93/153 (60%), Gaps = 4/153 (2%)
Frame = -2
Query: 683 LRNLD-LSKNKLSV--LPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFV 513
L+NL LS N +S+ LP+++ L +L L L N L LP+SL L++LE L++ NN +
Sbjct: 127 LQNLTCLSVNDISLQSLPENIGNLYNLASLELRENLLTYLPDSLTQLRRLEELDLGNNEI 186
Query: 512 QTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSEL-YVI 336
LP + L +LK ++ N+L P++I L++L LD+S N++ +P +S L +
Sbjct: 187 YNLPESIGALLHLKDLWLDGNQLSELPQEIGNLKNLLCLDVSENRLERLPEEISGLTSLT 246
Query: 335 ELNLSQNEISLIGEDLHQAPRLKILRLDENCLS 237
+L +SQN + I + + + +L IL++D+N L+
Sbjct: 247 DLVISQNLLETIPDGIGKLKKLSILKVDQNRLT 279
Score = 84.6 bits (200), Expect = 3e-16
Identities = 54/166 (32%), Positives = 92/166 (55%), Gaps = 1/166 (0%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESL 561
+++ +L+ +P ++ L L +L +S+N L +PD + KLK L L +D N+L LPE++
Sbjct: 227 VSENRLERLPEEISGLTS-LTDLVISQNLLETIPDGIGKLKKLSILKVDQNRLTQLPEAV 285
Query: 560 INLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHN 381
+ L L ++ N + TLP + L L + A NKL + PK+I G SL V + N
Sbjct: 286 GECESLTELVLTENQLLTLPKSIGKLKKLSNLNADRNKLVSLPKEIGGCCSLTVFCVRDN 345
Query: 380 KITEIPYGMSELYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDEN 246
++T IP +S+ + L+++ N + + L A +LK L L +N
Sbjct: 346 RLTRIPAEVSQATELHVLDVAGNRLLHLPLSL-TALKLKALWLSDN 390
Score = 82.6 bits (195), Expect = 1e-15
Identities = 55/187 (29%), Positives = 99/187 (52%), Gaps = 1/187 (0%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
++ EIP + S C L+ D S N L+ LP+ +L++L L+++ LQ+LPE++ NL
Sbjct: 93 EIPEIPESI-SFCKALQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLPENIGNLY 151
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITE 369
L L + N + LP L L L+++ NN++ P+ I L L L L N+++E
Sbjct: 152 NLASLELRENLLTYLPDSLTQLRRLEELDLGNNEIYNLPESIGALLHLKDLWLDGNQLSE 211
Query: 368 IPYGMSEL-YVIELNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIH 192
+P + L ++ L++S+N + + E++ L L + +N L+ I + + K+
Sbjct: 212 LPQEIGNLKNLLCLDVSENRLERLPEEISGLTSLTDLVISQNL--LETIPDGIGKLKKLS 269
Query: 191 TVSVDGN 171
+ VD N
Sbjct: 270 ILKVDQN 276
Score = 80.6 bits (190), Expect = 5e-15
Identities = 47/168 (27%), Positives = 93/168 (55%), Gaps = 1/168 (0%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESL 561
++D +++ +P ++ + ++ LD+S+N++ +P+ +S K L+ + N L LPES
Sbjct: 66 LSDNEIQRLPPEIANFMQLVE-LDVSRNEIPEIPESISFCKALQVADFSGNPLTRLPESF 124
Query: 560 INLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHN 381
L+ L L++++ +Q+LP + NL NL + N L P + L+ L+ LDL +N
Sbjct: 125 PELQNLTCLSVNDISLQSLPENIGNLYNLASLELRENLLTYLPDSLTQLRRLEELDLGNN 184
Query: 380 KITEIPYGMSE-LYVIELNLSQNEISLIGEDLHQAPRLKILRLDENCL 240
+I +P + L++ +L L N++S + +++ L L + EN L
Sbjct: 185 EIYNLPESIGALLHLKDLWLDGNQLSELPQEIGNLKNLLCLDVSENRL 232
Score = 78.6 bits (185), Expect = 2e-14
Identities = 47/164 (28%), Positives = 88/164 (53%), Gaps = 1/164 (0%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
+L E+P ++ +L ++L LD+S+N+L LP+++S L L L + N L+ +P+ + LK
Sbjct: 208 QLSELPQEIGNLKNLLC-LDVSENRLERLPEEISGLTSLTDLVISQNLLETIPDGIGKLK 266
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITE 369
KL +L + N + LP + +L ++ + N+L PK I L+ L L+ NK+
Sbjct: 267 KLSILKVDQNRLTQLPEAVGECESLTELVLTENQLLTLPKSIGKLKKLSNLNADRNKLVS 326
Query: 368 IPYGMSELYVIEL-NLSQNEISLIGEDLHQAPRLKILRLDENCL 240
+P + + + + N ++ I ++ QA L +L + N L
Sbjct: 327 LPKEIGGCCSLTVFCVRDNRLTRIPAEVSQATELHVLDVAGNRL 370
Score = 77.8 bits (183), Expect = 4e-14
Identities = 55/202 (27%), Positives = 97/202 (48%), Gaps = 4/202 (1%)
Frame = -2
Query: 731 CKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINL 552
C L +P +++ L L L N+L LP+ +L L++L L N++Q LP + N
Sbjct: 22 CSLVYVPEEIYRYARSLEELLLDANQLRELPEQFFQLVKLRKLGLSDNEIQRLPPEIANF 81
Query: 551 KKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKIT 372
+L L++S N + +P + L+ S N L P+ LQ+L L ++ +
Sbjct: 82 MQLVELDVSRNEIPEIPESISFCKALQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQ 141
Query: 371 EIPYGMSELY-VIELNLSQNEISLIGEDLHQAPRLKILRLDEN-CLSLDEIKPSLLRDSK 198
+P + LY + L L +N ++ + + L Q RL+ L L N +L E +LL
Sbjct: 142 SLPENIGNLYNLASLELRENLLTYLPDSLTQLRRLEELDLGNNEIYNLPESIGALLH--- 198
Query: 197 IHTVSVDGNLFE--PKQLAXLE 138
+ + +DGN P+++ L+
Sbjct: 199 LKDLWLDGNQLSELPQEIGNLK 220
Score = 66.1 bits (154), Expect = 1e-10
Identities = 42/138 (30%), Positives = 73/138 (52%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKK 546
L+ IP + L L L + +N+L+ LP+ + + + L +L L N+L LP+S+ LKK
Sbjct: 255 LETIPDGIGKL-KKLSILKVDQNRLTQLPEAVGECESLTELVLTENQLLTLPKSIGKLKK 313
Query: 545 LEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEI 366
L LN N + +LP + +L +N+L P ++ L VLD++ N++ +
Sbjct: 314 LSNLNADRNKLVSLPKEIGGCCSLTVFCVRDNRLTRIPAEVSQATELHVLDVAGNRLLHL 373
Query: 365 PYGMSELYVIELNLSQNE 312
P ++ L + L LS N+
Sbjct: 374 PLSLTALKLKALWLSDNQ 391
>AF359380-1|AAK72246.1| 524|Homo sapiens LANO adaptor protein
protein.
Length = 524
Score = 94.3 bits (224), Expect = 4e-19
Identities = 62/191 (32%), Positives = 109/191 (57%), Gaps = 1/191 (0%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESL 561
+ D L+ +P ++ +L + L +L+L +N L+ LPD L++L+ L++L+L +N++ LPES+
Sbjct: 135 VNDISLQSLPENIGNLYN-LASLELRENLLTYLPDSLTQLRRLEELDLGNNEIYNLPESI 193
Query: 560 INLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHN 381
L L+ L + N + LP + NL NL + S N+L+ P++I GL SL L +S N
Sbjct: 194 GALLHLKDLWLDGNQLSELPQEIGNLKNLLCLDVSENRLERLPEEISGLTSLTDLVISQN 253
Query: 380 KITEIPYGMSELYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRD 204
+ IP G+ +L + L + QN ++ + E + + L L L EN L + S+ +
Sbjct: 254 LLETIPDGIGKLKKLSILKVDQNRLTQLPEAVGECESLTELVLTEN--QLLTLPKSIGKL 311
Query: 203 SKIHTVSVDGN 171
K+ ++ D N
Sbjct: 312 KKLSNLNADRN 322
Score = 92.3 bits (219), Expect = 2e-18
Identities = 50/149 (33%), Positives = 83/149 (55%), Gaps = 1/149 (0%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTL 504
L LDL N++ LP+ + L HLK L LD N+L LP+ + NLK L L++S N ++ L
Sbjct: 176 LEELDLGNNEIYNLPESIGALLHLKDLWLDGNQLSELPQEIGNLKNLLCLDVSENRLERL 235
Query: 503 PVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSEL-YVIELN 327
P + L +L + S N L+ P I L+ L +L + N++T++P + E + EL
Sbjct: 236 PEEISGLTSLTDLVISQNLLETIPDGIGKLKKLSILKVDQNRLTQLPEAVGECESLTELV 295
Query: 326 LSQNEISLIGEDLHQAPRLKILRLDENCL 240
L++N++ + + + + +L L D N L
Sbjct: 296 LTENQLLTLPKSIGKLKKLSNLNADRNKL 324
Score = 90.2 bits (214), Expect = 7e-18
Identities = 54/153 (35%), Positives = 93/153 (60%), Gaps = 4/153 (2%)
Frame = -2
Query: 683 LRNLD-LSKNKLSV--LPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFV 513
L+NL LS N +S+ LP+++ L +L L L N L LP+SL L++LE L++ NN +
Sbjct: 127 LQNLTCLSVNDISLQSLPENIGNLYNLASLELRENLLTYLPDSLTQLRRLEELDLGNNEI 186
Query: 512 QTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSEL-YVI 336
LP + L +LK ++ N+L P++I L++L LD+S N++ +P +S L +
Sbjct: 187 YNLPESIGALLHLKDLWLDGNQLSELPQEIGNLKNLLCLDVSENRLERLPEEISGLTSLT 246
Query: 335 ELNLSQNEISLIGEDLHQAPRLKILRLDENCLS 237
+L +SQN + I + + + +L IL++D+N L+
Sbjct: 247 DLVISQNLLETIPDGIGKLKKLSILKVDQNRLT 279
Score = 84.6 bits (200), Expect = 3e-16
Identities = 54/166 (32%), Positives = 92/166 (55%), Gaps = 1/166 (0%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESL 561
+++ +L+ +P ++ L L +L +S+N L +PD + KLK L L +D N+L LPE++
Sbjct: 227 VSENRLERLPEEISGLTS-LTDLVISQNLLETIPDGIGKLKKLSILKVDQNRLTQLPEAV 285
Query: 560 INLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHN 381
+ L L ++ N + TLP + L L + A NKL + PK+I G SL V + N
Sbjct: 286 GECESLTELVLTENQLLTLPKSIGKLKKLSNLNADRNKLVSLPKEIGGCCSLTVFCVRDN 345
Query: 380 KITEIPYGMSELYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDEN 246
++T IP +S+ + L+++ N + + L A +LK L L +N
Sbjct: 346 RLTRIPAEVSQATELHVLDVAGNRLLHLPLSL-TALKLKALWLSDN 390
Score = 82.6 bits (195), Expect = 1e-15
Identities = 55/187 (29%), Positives = 99/187 (52%), Gaps = 1/187 (0%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
++ EIP + S C L+ D S N L+ LP+ +L++L L+++ LQ+LPE++ NL
Sbjct: 93 EIPEIPESI-SFCKALQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLPENIGNLY 151
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITE 369
L L + N + LP L L L+++ NN++ P+ I L L L L N+++E
Sbjct: 152 NLASLELRENLLTYLPDSLTQLRRLEELDLGNNEIYNLPESIGALLHLKDLWLDGNQLSE 211
Query: 368 IPYGMSEL-YVIELNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIH 192
+P + L ++ L++S+N + + E++ L L + +N L+ I + + K+
Sbjct: 212 LPQEIGNLKNLLCLDVSENRLERLPEEISGLTSLTDLVISQNL--LETIPDGIGKLKKLS 269
Query: 191 TVSVDGN 171
+ VD N
Sbjct: 270 ILKVDQN 276
Score = 80.6 bits (190), Expect = 5e-15
Identities = 47/168 (27%), Positives = 93/168 (55%), Gaps = 1/168 (0%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESL 561
++D +++ +P ++ + ++ LD+S+N++ +P+ +S K L+ + N L LPES
Sbjct: 66 LSDNEIQRLPPEIANFMQLVE-LDVSRNEIPEIPESISFCKALQVADFSGNPLTRLPESF 124
Query: 560 INLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHN 381
L+ L L++++ +Q+LP + NL NL + N L P + L+ L+ LDL +N
Sbjct: 125 PELQNLTCLSVNDISLQSLPENIGNLYNLASLELRENLLTYLPDSLTQLRRLEELDLGNN 184
Query: 380 KITEIPYGMSE-LYVIELNLSQNEISLIGEDLHQAPRLKILRLDENCL 240
+I +P + L++ +L L N++S + +++ L L + EN L
Sbjct: 185 EIYNLPESIGALLHLKDLWLDGNQLSELPQEIGNLKNLLCLDVSENRL 232
Score = 78.6 bits (185), Expect = 2e-14
Identities = 47/164 (28%), Positives = 88/164 (53%), Gaps = 1/164 (0%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
+L E+P ++ +L ++L LD+S+N+L LP+++S L L L + N L+ +P+ + LK
Sbjct: 208 QLSELPQEIGNLKNLLC-LDVSENRLERLPEEISGLTSLTDLVISQNLLETIPDGIGKLK 266
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITE 369
KL +L + N + LP + +L ++ + N+L PK I L+ L L+ NK+
Sbjct: 267 KLSILKVDQNRLTQLPEAVGECESLTELVLTENQLLTLPKSIGKLKKLSNLNADRNKLVS 326
Query: 368 IPYGMSELYVIEL-NLSQNEISLIGEDLHQAPRLKILRLDENCL 240
+P + + + + N ++ I ++ QA L +L + N L
Sbjct: 327 LPKEIGGCCSLTVFCVRDNRLTRIPAEVSQATELHVLDVAGNRL 370
Score = 77.8 bits (183), Expect = 4e-14
Identities = 55/202 (27%), Positives = 97/202 (48%), Gaps = 4/202 (1%)
Frame = -2
Query: 731 CKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINL 552
C L +P +++ L L L N+L LP+ +L L++L L N++Q LP + N
Sbjct: 22 CSLVYVPEEIYRYARSLEELLLDANQLRELPEQFFQLVKLRKLGLSDNEIQRLPPEIANF 81
Query: 551 KKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKIT 372
+L L++S N + +P + L+ S N L P+ LQ+L L ++ +
Sbjct: 82 MQLVELDVSRNEIPEIPESISFCKALQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQ 141
Query: 371 EIPYGMSELY-VIELNLSQNEISLIGEDLHQAPRLKILRLDEN-CLSLDEIKPSLLRDSK 198
+P + LY + L L +N ++ + + L Q RL+ L L N +L E +LL
Sbjct: 142 SLPENIGNLYNLASLELRENLLTYLPDSLTQLRRLEELDLGNNEIYNLPESIGALLH--- 198
Query: 197 IHTVSVDGNLFE--PKQLAXLE 138
+ + +DGN P+++ L+
Sbjct: 199 LKDLWLDGNQLSELPQEIGNLK 220
Score = 66.1 bits (154), Expect = 1e-10
Identities = 42/138 (30%), Positives = 73/138 (52%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKK 546
L+ IP + L L L + +N+L+ LP+ + + + L +L L N+L LP+S+ LKK
Sbjct: 255 LETIPDGIGKL-KKLSILKVDQNRLTQLPEAVGECESLTELVLTENQLLTLPKSIGKLKK 313
Query: 545 LEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEI 366
L LN N + +LP + +L +N+L P ++ L VLD++ N++ +
Sbjct: 314 LSNLNADRNKLVSLPKEIGGCCSLTVFCVRDNRLTRIPAEVSQATELHVLDVAGNRLLHL 373
Query: 365 PYGMSELYVIELNLSQNE 312
P ++ L + L LS N+
Sbjct: 374 PLSLTALKLKALWLSDNQ 391
>AF332199-1|AAK69623.1| 524|Homo sapiens leucine-rich repeats
protein protein.
Length = 524
Score = 94.3 bits (224), Expect = 4e-19
Identities = 62/191 (32%), Positives = 109/191 (57%), Gaps = 1/191 (0%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESL 561
+ D L+ +P ++ +L + L +L+L +N L+ LPD L++L+ L++L+L +N++ LPES+
Sbjct: 135 VNDISLQSLPENIGNLYN-LASLELRENLLTYLPDSLTQLRRLEELDLGNNEIYNLPESI 193
Query: 560 INLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHN 381
L L+ L + N + LP + NL NL + S N+L+ P++I GL SL L +S N
Sbjct: 194 GALLHLKDLWLDGNQLSELPQEIGNLKNLLCLDVSENRLERLPEEISGLTSLTDLVISQN 253
Query: 380 KITEIPYGMSELYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRD 204
+ IP G+ +L + L + QN ++ + E + + L L L EN L + S+ +
Sbjct: 254 LLETIPDGIGKLKKLSILKVDQNRLTQLPEAVGECESLTELVLTEN--QLLTLPKSIGKL 311
Query: 203 SKIHTVSVDGN 171
K+ ++ D N
Sbjct: 312 KKLSNLNADRN 322
Score = 92.3 bits (219), Expect = 2e-18
Identities = 50/149 (33%), Positives = 83/149 (55%), Gaps = 1/149 (0%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTL 504
L LDL N++ LP+ + L HLK L LD N+L LP+ + NLK L L++S N ++ L
Sbjct: 176 LEELDLGNNEIYNLPESIGALLHLKDLWLDGNQLSELPQEIGNLKNLLCLDVSENRLERL 235
Query: 503 PVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSEL-YVIELN 327
P + L +L + S N L+ P I L+ L +L + N++T++P + E + EL
Sbjct: 236 PEEISGLTSLTDLVISQNLLETIPDGIGKLKKLSILKVDQNRLTQLPEAVGECESLTELV 295
Query: 326 LSQNEISLIGEDLHQAPRLKILRLDENCL 240
L++N++ + + + + +L L D N L
Sbjct: 296 LTENQLLTLPKSIGKLKKLSNLNADRNKL 324
Score = 90.2 bits (214), Expect = 7e-18
Identities = 54/153 (35%), Positives = 93/153 (60%), Gaps = 4/153 (2%)
Frame = -2
Query: 683 LRNLD-LSKNKLSV--LPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFV 513
L+NL LS N +S+ LP+++ L +L L L N L LP+SL L++LE L++ NN +
Sbjct: 127 LQNLTCLSVNDISLQSLPENIGNLYNLASLELRENLLTYLPDSLTQLRRLEELDLGNNEI 186
Query: 512 QTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSEL-YVI 336
LP + L +LK ++ N+L P++I L++L LD+S N++ +P +S L +
Sbjct: 187 YNLPESIGALLHLKDLWLDGNQLSELPQEIGNLKNLLCLDVSENRLERLPEEISGLTSLT 246
Query: 335 ELNLSQNEISLIGEDLHQAPRLKILRLDENCLS 237
+L +SQN + I + + + +L IL++D+N L+
Sbjct: 247 DLVISQNLLETIPDGIGKLKKLSILKVDQNRLT 279
Score = 84.6 bits (200), Expect = 3e-16
Identities = 54/166 (32%), Positives = 92/166 (55%), Gaps = 1/166 (0%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESL 561
+++ +L+ +P ++ L L +L +S+N L +PD + KLK L L +D N+L LPE++
Sbjct: 227 VSENRLERLPEEISGLTS-LTDLVISQNLLETIPDGIGKLKKLSILKVDQNRLTQLPEAV 285
Query: 560 INLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHN 381
+ L L ++ N + TLP + L L + A NKL + PK+I G SL V + N
Sbjct: 286 GECESLTELVLTENQLLTLPKSIGKLKKLSNLNADRNKLVSLPKEIGGCCSLTVFCVRDN 345
Query: 380 KITEIPYGMSELYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDEN 246
++T IP +S+ + L+++ N + + L A +LK L L +N
Sbjct: 346 RLTRIPAEVSQATELHVLDVAGNRLLHLPLSL-TALKLKALWLSDN 390
Score = 82.6 bits (195), Expect = 1e-15
Identities = 55/187 (29%), Positives = 99/187 (52%), Gaps = 1/187 (0%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
++ EIP + S C L+ D S N L+ LP+ +L++L L+++ LQ+LPE++ NL
Sbjct: 93 EIPEIPESI-SFCKALQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLPENIGNLY 151
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITE 369
L L + N + LP L L L+++ NN++ P+ I L L L L N+++E
Sbjct: 152 NLASLELRENLLTYLPDSLTQLRRLEELDLGNNEIYNLPESIGALLHLKDLWLDGNQLSE 211
Query: 368 IPYGMSEL-YVIELNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIH 192
+P + L ++ L++S+N + + E++ L L + +N L+ I + + K+
Sbjct: 212 LPQEIGNLKNLLCLDVSENRLERLPEEISGLTSLTDLVISQNL--LETIPDGIGKLKKLS 269
Query: 191 TVSVDGN 171
+ VD N
Sbjct: 270 ILKVDQN 276
Score = 80.6 bits (190), Expect = 5e-15
Identities = 47/168 (27%), Positives = 93/168 (55%), Gaps = 1/168 (0%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESL 561
++D +++ +P ++ + ++ LD+S+N++ +P+ +S K L+ + N L LPES
Sbjct: 66 LSDNEIQRLPPEIANFMQLVE-LDVSRNEIPEIPESISFCKALQVADFSGNPLTRLPESF 124
Query: 560 INLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHN 381
L+ L L++++ +Q+LP + NL NL + N L P + L+ L+ LDL +N
Sbjct: 125 PELQNLTCLSVNDISLQSLPENIGNLYNLASLELRENLLTYLPDSLTQLRRLEELDLGNN 184
Query: 380 KITEIPYGMSE-LYVIELNLSQNEISLIGEDLHQAPRLKILRLDENCL 240
+I +P + L++ +L L N++S + +++ L L + EN L
Sbjct: 185 EIYNLPESIGALLHLKDLWLDGNQLSELPQEIGNLKNLLCLDVSENRL 232
Score = 78.6 bits (185), Expect = 2e-14
Identities = 47/164 (28%), Positives = 88/164 (53%), Gaps = 1/164 (0%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
+L E+P ++ +L ++L LD+S+N+L LP+++S L L L + N L+ +P+ + LK
Sbjct: 208 QLSELPQEIGNLKNLLC-LDVSENRLERLPEEISGLTSLTDLVISQNLLETIPDGIGKLK 266
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITE 369
KL +L + N + LP + +L ++ + N+L PK I L+ L L+ NK+
Sbjct: 267 KLSILKVDQNRLTQLPEAVGECESLTELVLTENQLLTLPKSIGKLKKLSNLNADRNKLVS 326
Query: 368 IPYGMSELYVIEL-NLSQNEISLIGEDLHQAPRLKILRLDENCL 240
+P + + + + N ++ I ++ QA L +L + N L
Sbjct: 327 LPKEIGGCCSLTVFCVRDNRLTRIPAEVSQATELHVLDVAGNRL 370
Score = 77.8 bits (183), Expect = 4e-14
Identities = 55/202 (27%), Positives = 97/202 (48%), Gaps = 4/202 (1%)
Frame = -2
Query: 731 CKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINL 552
C L +P +++ L L L N+L LP+ +L L++L L N++Q LP + N
Sbjct: 22 CSLVYVPEEIYRYARSLEELLLDANQLRELPEQFFQLVKLRKLGLSDNEIQRLPPEIANF 81
Query: 551 KKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKIT 372
+L L++S N + +P + L+ S N L P+ LQ+L L ++ +
Sbjct: 82 MQLVELDVSRNEIPEIPESISFCKALQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQ 141
Query: 371 EIPYGMSELY-VIELNLSQNEISLIGEDLHQAPRLKILRLDEN-CLSLDEIKPSLLRDSK 198
+P + LY + L L +N ++ + + L Q RL+ L L N +L E +LL
Sbjct: 142 SLPENIGNLYNLASLELRENLLTYLPDSLTQLRRLEELDLGNNEIYNLPESIGALLH--- 198
Query: 197 IHTVSVDGNLFE--PKQLAXLE 138
+ + +DGN P+++ L+
Sbjct: 199 LKDLWLDGNQLSELPQEIGNLK 220
Score = 66.1 bits (154), Expect = 1e-10
Identities = 42/138 (30%), Positives = 73/138 (52%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKK 546
L+ IP + L L L + +N+L+ LP+ + + + L +L L N+L LP+S+ LKK
Sbjct: 255 LETIPDGIGKL-KKLSILKVDQNRLTQLPEAVGECESLTELVLTENQLLTLPKSIGKLKK 313
Query: 545 LEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEI 366
L LN N + +LP + +L +N+L P ++ L VLD++ N++ +
Sbjct: 314 LSNLNADRNKLVSLPKEIGGCCSLTVFCVRDNRLTRIPAEVSQATELHVLDVAGNRLLHL 373
Query: 365 PYGMSELYVIELNLSQNE 312
P ++ L + L LS N+
Sbjct: 374 PLSLTALKLKALWLSDNQ 391
>BC115015-1|AAI15016.1| 1367|Homo sapiens ERBB2IP protein protein.
Length = 1367
Score = 91.5 bits (217), Expect = 3e-18
Identities = 56/193 (29%), Positives = 107/193 (55%), Gaps = 4/193 (2%)
Frame = -2
Query: 689 DVLRNLDLSKNKLSVLPDDLSKL-KHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFV 513
+ + LD S L +P ++ K L++L LD+N+++ LP+ L N + L L++ +N +
Sbjct: 22 ETVTTLDYSHCSLEQVPKEIFTFEKTLEELYLDANQIEELPKQLFNCQSLHKLSLPDNDL 81
Query: 512 QTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELY-VI 336
TLP + NL NL+++ S N +Q FP+ I + L +++ S N I+++P G S+L +
Sbjct: 82 TTLPASIANLINLRELDVSKNGIQEFPENIKNCKVLTIVEASVNPISKLPDGFSQLLNLT 141
Query: 335 ELNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIHTVSVDGNLFE-- 162
+L L+ + + + + +L+IL L EN L + + ++ R +++ + + N F
Sbjct: 142 QLYLNDAFLEFLPANFDRLTKLQILELRENQLKM--LPKTMNRLTQLERLDLGSNEFTEV 199
Query: 161 PKQLAXLEGYNEY 123
P+ L L G E+
Sbjct: 200 PEVLEQLSGLKEF 212
Score = 89.4 bits (212), Expect = 1e-17
Identities = 53/165 (32%), Positives = 89/165 (53%), Gaps = 1/165 (0%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
+++E+P +F+ C L L L N L+ LP ++ L +L++L++ N +Q PE++ N K
Sbjct: 57 QIEELPKQLFN-CQSLHKLSLPDNDLTTLPASIANLINLRELDVSKNGIQEFPENIKNCK 115
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITE 369
L ++ S N + LP L NL Q+Y ++ L+ P L L +L+L N++
Sbjct: 116 VLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPANFDRLTKLQILELRENQLKM 175
Query: 368 IPYGMSELYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDENCLS 237
+P M+ L +E L+L NE + + E L Q LK +D N L+
Sbjct: 176 LPKTMNRLTQLERLDLGSNEFTEVPEVLEQLSGLKEFWMDANRLT 220
Score = 87.8 bits (208), Expect = 4e-17
Identities = 50/152 (32%), Positives = 84/152 (55%), Gaps = 1/152 (0%)
Frame = -2
Query: 698 SLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNN 519
S C+ L++L LS N L LP+ + LK++ L +D N+L LP+S+ L +E L+ S N
Sbjct: 250 STCENLQDLLLSSNSLQQLPETIGSLKNITTLKIDENQLMYLPDSIGGLISVEELDCSFN 309
Query: 518 FVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYV 339
V+ LP + L NL+ A +N LQ P +I +++ VL L NK+ +P M ++
Sbjct: 310 EVEALPSSIGQLTNLRTFAADHNYLQQLPPEIGSWKNITVLFLHSNKLETLPEEMGDMQK 369
Query: 338 IE-LNLSQNEISLIGEDLHQAPRLKILRLDEN 246
++ +NLS N + + + +L + L +N
Sbjct: 370 LKVINLSDNRLKNLPFSFTKLQQLTAMWLSDN 401
Score = 81.8 bits (193), Expect = 2e-15
Identities = 53/200 (26%), Positives = 102/200 (51%), Gaps = 3/200 (1%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
+LK +P + L L LDL N+ + +P+ L +L LK+ +D+N+L +P + +LK
Sbjct: 172 QLKMLPKTMNRLTQ-LERLDLGSNEFTEVPEVLEQLSGLKEFWMDANRLTFIPGFIGSLK 230
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITE 369
+L L++S N ++ + + NL+ + S+N LQ P+ I L+++ L + N++
Sbjct: 231 QLTYLDVSKNNIEMVEEGISTCENLQDLLLSSNSLQQLPETIGSLKNITTLKIDENQLMY 290
Query: 368 IPYGMSELY-VIELNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIH 192
+P + L V EL+ S NE+ + + Q L+ D N L ++ P + I
Sbjct: 291 LPDSIGGLISVEELDCSFNEVEALPSSIGQLTNLRTFAADHN--YLQQLPPEIGSWKNIT 348
Query: 191 TVSVDGNLFE--PKQLAXLE 138
+ + N E P+++ ++
Sbjct: 349 VLFLHSNKLETLPEEMGDMQ 368
Score = 79.8 bits (188), Expect = 9e-15
Identities = 56/203 (27%), Positives = 103/203 (50%), Gaps = 3/203 (1%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKK 546
++E P ++ + C VL ++ S N +S LPD S+L +L QL L+ L+ LP + L K
Sbjct: 104 IQEFPENIKN-CKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPANFDRLTK 162
Query: 545 LEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEI 366
L++L + N ++ LP + L L+++ +N+ P+ + L L + N++T I
Sbjct: 163 LQILELRENQLKMLPKTMNRLTQLERLDLGSNEFTEVPEVLEQLSGLKEFWMDANRLTFI 222
Query: 365 PYGMSEL-YVIELNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIHT 189
P + L + L++S+N I ++ E + L+ L L N SL ++ ++ I T
Sbjct: 223 PGFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQDLLLSSN--SLQQLPETIGSLKNITT 280
Query: 188 VSVDGN--LFEPKQLAXLEGYNE 126
+ +D N ++ P + L E
Sbjct: 281 LKIDENQLMYLPDSIGGLISVEE 303
Score = 78.6 bits (185), Expect = 2e-14
Identities = 48/163 (29%), Positives = 82/163 (50%), Gaps = 1/163 (0%)
Frame = -2
Query: 731 CKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINL 552
C L+++P ++F+ L L L N++ LP L + L +L+L N L LP S+ NL
Sbjct: 32 CSLEQVPKEIFTFEKTLEELYLDANQIEELPKQLFNCQSLHKLSLPDNDLTTLPASIANL 91
Query: 551 KKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKIT 372
L L++S N +Q P +KN L V AS N + P L +L L L+ +
Sbjct: 92 INLRELDVSKNGIQEFPENIKNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLE 151
Query: 371 EIPYGMSELYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDEN 246
+P L ++ L L +N++ ++ + +++ +L+ L L N
Sbjct: 152 FLPANFDRLTKLQILELRENQLKMLPKTMNRLTQLERLDLGSN 194
Score = 63.3 bits (147), Expect = 9e-10
Identities = 38/121 (31%), Positives = 64/121 (52%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESL 561
I + +L +P + L V LD S N++ LP + +L +L+ D N LQ LP +
Sbjct: 283 IDENQLMYLPDSIGGLISV-EELDCSFNEVEALPSSIGQLTNLRTFAADHNYLQQLPPEI 341
Query: 560 INLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHN 381
+ K + VL + +N ++TLP + ++ LK + S+N+L+ P LQ L + LS N
Sbjct: 342 GSWKNITVLFLHSNKLETLPEEMGDMQKLKVINLSDNRLKNLPFSFTKLQQLTAMWLSDN 401
Query: 380 K 378
+
Sbjct: 402 Q 402
>BC126464-1|AAI26465.1| 1371|Homo sapiens erbb2 interacting protein
protein.
Length = 1371
Score = 91.1 bits (216), Expect = 4e-18
Identities = 56/193 (29%), Positives = 107/193 (55%), Gaps = 4/193 (2%)
Frame = -2
Query: 689 DVLRNLDLSKNKLSVLPDDLSKL-KHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFV 513
+ + LD S L +P ++ K L++L LD+N+++ LP+ L N + L L++ +N +
Sbjct: 22 ETVTTLDYSHCSLEQVPKEIFTFEKTLEELYLDANQIEELPKQLFNCQSLHKLSLPDNDL 81
Query: 512 QTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELY-VI 336
TLP + NL NL+++ S N +Q FP+ I + L +++ S N I+++P G S+L +
Sbjct: 82 TTLPASIANLINLRELDVSKNGIQEFPENIKNCKVLTIVEASVNPISKLPDGFSQLLNLT 141
Query: 335 ELNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIHTVSVDGNLFE-- 162
+L L+ + + + + +L+IL L EN L + + ++ R +++ + + N F
Sbjct: 142 QLYLNDAFLEFLPANFGRLTKLQILELRENQLKM--LPKTMNRLTQLERLDLGSNEFTEV 199
Query: 161 PKQLAXLEGYNEY 123
P+ L L G E+
Sbjct: 200 PEVLEQLSGLKEF 212
Score = 89.4 bits (212), Expect = 1e-17
Identities = 53/165 (32%), Positives = 89/165 (53%), Gaps = 1/165 (0%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
+++E+P +F+ C L L L N L+ LP ++ L +L++L++ N +Q PE++ N K
Sbjct: 57 QIEELPKQLFN-CQSLHKLSLPDNDLTTLPASIANLINLRELDVSKNGIQEFPENIKNCK 115
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITE 369
L ++ S N + LP L NL Q+Y ++ L+ P L L +L+L N++
Sbjct: 116 VLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPANFGRLTKLQILELRENQLKM 175
Query: 368 IPYGMSELYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDENCLS 237
+P M+ L +E L+L NE + + E L Q LK +D N L+
Sbjct: 176 LPKTMNRLTQLERLDLGSNEFTEVPEVLEQLSGLKEFWMDANRLT 220
Score = 87.0 bits (206), Expect = 6e-17
Identities = 50/152 (32%), Positives = 84/152 (55%), Gaps = 1/152 (0%)
Frame = -2
Query: 698 SLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNN 519
S C+ L++L LS N L LP+ + LK++ L +D N+L LP+S+ L +E L+ S N
Sbjct: 250 STCENLQDLLLSSNSLQQLPETIGLLKNITTLKIDENQLMYLPDSIGGLISVEELDCSFN 309
Query: 518 FVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYV 339
V+ LP + L NL+ A +N LQ P +I +++ VL L NK+ +P M ++
Sbjct: 310 EVEALPSSIGQLTNLRTFAADHNYLQQLPPEIGSWKNITVLFLHSNKLETLPEEMGDMQK 369
Query: 338 IE-LNLSQNEISLIGEDLHQAPRLKILRLDEN 246
++ +NLS N + + + +L + L +N
Sbjct: 370 LKVINLSDNRLKNLPFSFTKLQQLTAMWLSDN 401
Score = 80.2 bits (189), Expect = 7e-15
Identities = 53/200 (26%), Positives = 102/200 (51%), Gaps = 3/200 (1%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
+LK +P + L L LDL N+ + +P+ L +L LK+ +D+N+L +P + +LK
Sbjct: 172 QLKMLPKTMNRLTQ-LERLDLGSNEFTEVPEVLEQLSGLKEFWMDANRLTFIPGFIGSLK 230
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITE 369
+L L++S N ++ + + NL+ + S+N LQ P+ I L+++ L + N++
Sbjct: 231 QLTYLDVSKNNIEMVEEGISTCENLQDLLLSSNSLQQLPETIGLLKNITTLKIDENQLMY 290
Query: 368 IPYGMSELY-VIELNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIH 192
+P + L V EL+ S NE+ + + Q L+ D N L ++ P + I
Sbjct: 291 LPDSIGGLISVEELDCSFNEVEALPSSIGQLTNLRTFAADHN--YLQQLPPEIGSWKNIT 348
Query: 191 TVSVDGNLFE--PKQLAXLE 138
+ + N E P+++ ++
Sbjct: 349 VLFLHSNKLETLPEEMGDMQ 368
Score = 79.0 bits (186), Expect = 2e-14
Identities = 56/203 (27%), Positives = 103/203 (50%), Gaps = 3/203 (1%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKK 546
++E P ++ + C VL ++ S N +S LPD S+L +L QL L+ L+ LP + L K
Sbjct: 104 IQEFPENIKN-CKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPANFGRLTK 162
Query: 545 LEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEI 366
L++L + N ++ LP + L L+++ +N+ P+ + L L + N++T I
Sbjct: 163 LQILELRENQLKMLPKTMNRLTQLERLDLGSNEFTEVPEVLEQLSGLKEFWMDANRLTFI 222
Query: 365 PYGMSEL-YVIELNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIHT 189
P + L + L++S+N I ++ E + L+ L L N SL ++ ++ I T
Sbjct: 223 PGFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQDLLLSSN--SLQQLPETIGLLKNITT 280
Query: 188 VSVDGN--LFEPKQLAXLEGYNE 126
+ +D N ++ P + L E
Sbjct: 281 LKIDENQLMYLPDSIGGLISVEE 303
Score = 78.6 bits (185), Expect = 2e-14
Identities = 48/163 (29%), Positives = 82/163 (50%), Gaps = 1/163 (0%)
Frame = -2
Query: 731 CKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINL 552
C L+++P ++F+ L L L N++ LP L + L +L+L N L LP S+ NL
Sbjct: 32 CSLEQVPKEIFTFEKTLEELYLDANQIEELPKQLFNCQSLHKLSLPDNDLTTLPASIANL 91
Query: 551 KKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKIT 372
L L++S N +Q P +KN L V AS N + P L +L L L+ +
Sbjct: 92 INLRELDVSKNGIQEFPENIKNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLE 151
Query: 371 EIPYGMSELYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDEN 246
+P L ++ L L +N++ ++ + +++ +L+ L L N
Sbjct: 152 FLPANFGRLTKLQILELRENQLKMLPKTMNRLTQLERLDLGSN 194
Score = 75.8 bits (178), Expect = 2e-13
Identities = 38/139 (27%), Positives = 80/139 (57%), Gaps = 1/139 (0%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKK 546
L+++P + L + L + +N+L LPD + L +++L+ N+++ALP S+ L
Sbjct: 265 LQQLP-ETIGLLKNITTLKIDENQLMYLPDSIGGLISVEELDCSFNEVEALPSSIGQLTN 323
Query: 545 LEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEI 366
L +N++Q LP + + N+ ++ +NKL+ P+++ +Q L V++LS N++ +
Sbjct: 324 LRTFAADHNYLQQLPPEIGSWKNITVLFLHSNKLETLPEEMGDMQKLKVINLSDNRLKNL 383
Query: 365 PYGMSEL-YVIELNLSQNE 312
P+ ++L + + LS N+
Sbjct: 384 PFSFTKLQQLTAMWLSDNQ 402
>BC115012-1|AAI15013.1| 1371|Homo sapiens erbb2 interacting protein
protein.
Length = 1371
Score = 91.1 bits (216), Expect = 4e-18
Identities = 56/193 (29%), Positives = 107/193 (55%), Gaps = 4/193 (2%)
Frame = -2
Query: 689 DVLRNLDLSKNKLSVLPDDLSKL-KHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFV 513
+ + LD S L +P ++ K L++L LD+N+++ LP+ L N + L L++ +N +
Sbjct: 22 ETVTTLDYSHCSLEQVPKEIFTFEKTLEELYLDANQIEELPKQLFNCQSLHKLSLPDNDL 81
Query: 512 QTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELY-VI 336
TLP + NL NL+++ S N +Q FP+ I + L +++ S N I+++P G S+L +
Sbjct: 82 TTLPASIANLINLRELDVSKNGIQEFPENIKNCKVLTIVEASVNPISKLPDGFSQLLNLT 141
Query: 335 ELNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIHTVSVDGNLFE-- 162
+L L+ + + + + +L+IL L EN L + + ++ R +++ + + N F
Sbjct: 142 QLYLNDAFLEFLPANFGRLTKLQILELRENQLKM--LPKTMNRLTQLERLDLGSNEFTEV 199
Query: 161 PKQLAXLEGYNEY 123
P+ L L G E+
Sbjct: 200 PEVLEQLSGLKEF 212
Score = 89.4 bits (212), Expect = 1e-17
Identities = 53/165 (32%), Positives = 89/165 (53%), Gaps = 1/165 (0%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
+++E+P +F+ C L L L N L+ LP ++ L +L++L++ N +Q PE++ N K
Sbjct: 57 QIEELPKQLFN-CQSLHKLSLPDNDLTTLPASIANLINLRELDVSKNGIQEFPENIKNCK 115
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITE 369
L ++ S N + LP L NL Q+Y ++ L+ P L L +L+L N++
Sbjct: 116 VLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPANFGRLTKLQILELRENQLKM 175
Query: 368 IPYGMSELYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDENCLS 237
+P M+ L +E L+L NE + + E L Q LK +D N L+
Sbjct: 176 LPKTMNRLTQLERLDLGSNEFTEVPEVLEQLSGLKEFWMDANRLT 220
Score = 87.8 bits (208), Expect = 4e-17
Identities = 50/152 (32%), Positives = 84/152 (55%), Gaps = 1/152 (0%)
Frame = -2
Query: 698 SLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNN 519
S C+ L++L LS N L LP+ + LK++ L +D N+L LP+S+ L +E L+ S N
Sbjct: 250 STCENLQDLLLSSNSLQQLPEPIGSLKNITTLKIDENQLMYLPDSIGGLISVEELDCSFN 309
Query: 518 FVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYV 339
V+ LP + L NL+ A +N LQ P +I +++ VL L NK+ +P M ++
Sbjct: 310 EVEALPSSIGQLTNLRTFAADHNYLQQLPPEIGSWKNITVLFLHSNKLETLPEEMGDMQK 369
Query: 338 IE-LNLSQNEISLIGEDLHQAPRLKILRLDEN 246
++ +NLS N + + + +L + L +N
Sbjct: 370 LKVINLSDNRLKNLPFSFTKLQQLTAMWLSDN 401
Score = 81.8 bits (193), Expect = 2e-15
Identities = 53/200 (26%), Positives = 102/200 (51%), Gaps = 3/200 (1%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
+LK +P + L L LDL N+ + +P+ L +L LK+ +D+N+L +P + +LK
Sbjct: 172 QLKMLPKTMNRLTQ-LERLDLGSNEFTEVPEVLEQLSGLKEFWMDANRLTFIPGFIGSLK 230
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITE 369
+L L++S N ++ + + NL+ + S+N LQ P+ I L+++ L + N++
Sbjct: 231 QLTYLDVSKNNIEMVEEGISTCENLQDLLLSSNSLQQLPEPIGSLKNITTLKIDENQLMY 290
Query: 368 IPYGMSELY-VIELNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIH 192
+P + L V EL+ S NE+ + + Q L+ D N L ++ P + I
Sbjct: 291 LPDSIGGLISVEELDCSFNEVEALPSSIGQLTNLRTFAADHN--YLQQLPPEIGSWKNIT 348
Query: 191 TVSVDGNLFE--PKQLAXLE 138
+ + N E P+++ ++
Sbjct: 349 VLFLHSNKLETLPEEMGDMQ 368
Score = 78.6 bits (185), Expect = 2e-14
Identities = 48/163 (29%), Positives = 82/163 (50%), Gaps = 1/163 (0%)
Frame = -2
Query: 731 CKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINL 552
C L+++P ++F+ L L L N++ LP L + L +L+L N L LP S+ NL
Sbjct: 32 CSLEQVPKEIFTFEKTLEELYLDANQIEELPKQLFNCQSLHKLSLPDNDLTTLPASIANL 91
Query: 551 KKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKIT 372
L L++S N +Q P +KN L V AS N + P L +L L L+ +
Sbjct: 92 INLRELDVSKNGIQEFPENIKNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLE 151
Query: 371 EIPYGMSELYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDEN 246
+P L ++ L L +N++ ++ + +++ +L+ L L N
Sbjct: 152 FLPANFGRLTKLQILELRENQLKMLPKTMNRLTQLERLDLGSN 194
Score = 78.6 bits (185), Expect = 2e-14
Identities = 56/203 (27%), Positives = 102/203 (50%), Gaps = 3/203 (1%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKK 546
++E P ++ + C VL ++ S N +S LPD S+L +L QL L+ L+ LP + L K
Sbjct: 104 IQEFPENIKN-CKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPANFGRLTK 162
Query: 545 LEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEI 366
L++L + N ++ LP + L L+++ +N+ P+ + L L + N++T I
Sbjct: 163 LQILELRENQLKMLPKTMNRLTQLERLDLGSNEFTEVPEVLEQLSGLKEFWMDANRLTFI 222
Query: 365 PYGMSEL-YVIELNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIHT 189
P + L + L++S+N I ++ E + L+ L L N SL ++ + I T
Sbjct: 223 PGFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQDLLLSSN--SLQQLPEPIGSLKNITT 280
Query: 188 VSVDGN--LFEPKQLAXLEGYNE 126
+ +D N ++ P + L E
Sbjct: 281 LKIDENQLMYLPDSIGGLISVEE 303
Score = 63.3 bits (147), Expect = 9e-10
Identities = 38/121 (31%), Positives = 64/121 (52%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESL 561
I + +L +P + L V LD S N++ LP + +L +L+ D N LQ LP +
Sbjct: 283 IDENQLMYLPDSIGGLISV-EELDCSFNEVEALPSSIGQLTNLRTFAADHNYLQQLPPEI 341
Query: 560 INLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHN 381
+ K + VL + +N ++TLP + ++ LK + S+N+L+ P LQ L + LS N
Sbjct: 342 GSWKNITVLFLHSNKLETLPEEMGDMQKLKVINLSDNRLKNLPFSFTKLQQLTAMWLSDN 401
Query: 380 K 378
+
Sbjct: 402 Q 402
>BC050692-1|AAH50692.1| 633|Homo sapiens ERBB2IP protein protein.
Length = 633
Score = 91.1 bits (216), Expect = 4e-18
Identities = 56/193 (29%), Positives = 107/193 (55%), Gaps = 4/193 (2%)
Frame = -2
Query: 689 DVLRNLDLSKNKLSVLPDDLSKL-KHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFV 513
+ + LD S L +P ++ K L++L LD+N+++ LP+ L N + L L++ +N +
Sbjct: 22 ETVTTLDYSHCSLEQVPKEIFTFEKTLEELYLDANQIEELPKQLFNCQSLHKLSLPDNDL 81
Query: 512 QTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELY-VI 336
TLP + NL NL+++ S N +Q FP+ I + L +++ S N I+++P G S+L +
Sbjct: 82 TTLPASIANLINLRELDVSKNGIQEFPENIKNCKVLTIVEASVNPISKLPDGFSQLLNLT 141
Query: 335 ELNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIHTVSVDGNLFE-- 162
+L L+ + + + + +L+IL L EN L + + ++ R +++ + + N F
Sbjct: 142 QLYLNDAFLEFLPANFGRLTKLQILELRENQLKM--LPKTMNRLTQLERLDLGSNEFTEV 199
Query: 161 PKQLAXLEGYNEY 123
P+ L L G E+
Sbjct: 200 PEVLEQLSGLKEF 212
Score = 89.4 bits (212), Expect = 1e-17
Identities = 53/165 (32%), Positives = 89/165 (53%), Gaps = 1/165 (0%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
+++E+P +F+ C L L L N L+ LP ++ L +L++L++ N +Q PE++ N K
Sbjct: 57 QIEELPKQLFN-CQSLHKLSLPDNDLTTLPASIANLINLRELDVSKNGIQEFPENIKNCK 115
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITE 369
L ++ S N + LP L NL Q+Y ++ L+ P L L +L+L N++
Sbjct: 116 VLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPANFGRLTKLQILELRENQLKM 175
Query: 368 IPYGMSELYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDENCLS 237
+P M+ L +E L+L NE + + E L Q LK +D N L+
Sbjct: 176 LPKTMNRLTQLERLDLGSNEFTEVPEVLEQLSGLKEFWMDANRLT 220
Score = 87.8 bits (208), Expect = 4e-17
Identities = 50/152 (32%), Positives = 84/152 (55%), Gaps = 1/152 (0%)
Frame = -2
Query: 698 SLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNN 519
S C+ L++L LS N L LP+ + LK++ L +D N+L LP+S+ L +E L+ S N
Sbjct: 250 STCENLQDLLLSSNSLQQLPETIGSLKNITTLKIDENQLMYLPDSIGGLISVEELDCSFN 309
Query: 518 FVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYV 339
V+ LP + L NL+ A +N LQ P +I +++ VL L NK+ +P M ++
Sbjct: 310 EVEALPSSIGQLTNLRTFAADHNYLQQLPPEIGSWKNITVLFLHSNKLETLPEEMGDMQK 369
Query: 338 IE-LNLSQNEISLIGEDLHQAPRLKILRLDEN 246
++ +NLS N + + + +L + L +N
Sbjct: 370 LKVINLSDNRLKNLPFSFTKLQQLTAMWLSDN 401
Score = 81.8 bits (193), Expect = 2e-15
Identities = 53/200 (26%), Positives = 102/200 (51%), Gaps = 3/200 (1%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
+LK +P + L L LDL N+ + +P+ L +L LK+ +D+N+L +P + +LK
Sbjct: 172 QLKMLPKTMNRLTQ-LERLDLGSNEFTEVPEVLEQLSGLKEFWMDANRLTFIPGFIGSLK 230
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITE 369
+L L++S N ++ + + NL+ + S+N LQ P+ I L+++ L + N++
Sbjct: 231 QLTYLDVSKNNIEMVEEGISTCENLQDLLLSSNSLQQLPETIGSLKNITTLKIDENQLMY 290
Query: 368 IPYGMSELY-VIELNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIH 192
+P + L V EL+ S NE+ + + Q L+ D N L ++ P + I
Sbjct: 291 LPDSIGGLISVEELDCSFNEVEALPSSIGQLTNLRTFAADHN--YLQQLPPEIGSWKNIT 348
Query: 191 TVSVDGNLFE--PKQLAXLE 138
+ + N E P+++ ++
Sbjct: 349 VLFLHSNKLETLPEEMGDMQ 368
Score = 79.4 bits (187), Expect = 1e-14
Identities = 56/203 (27%), Positives = 103/203 (50%), Gaps = 3/203 (1%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKK 546
++E P ++ + C VL ++ S N +S LPD S+L +L QL L+ L+ LP + L K
Sbjct: 104 IQEFPENIKN-CKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPANFGRLTK 162
Query: 545 LEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEI 366
L++L + N ++ LP + L L+++ +N+ P+ + L L + N++T I
Sbjct: 163 LQILELRENQLKMLPKTMNRLTQLERLDLGSNEFTEVPEVLEQLSGLKEFWMDANRLTFI 222
Query: 365 PYGMSEL-YVIELNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIHT 189
P + L + L++S+N I ++ E + L+ L L N SL ++ ++ I T
Sbjct: 223 PGFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQDLLLSSN--SLQQLPETIGSLKNITT 280
Query: 188 VSVDGN--LFEPKQLAXLEGYNE 126
+ +D N ++ P + L E
Sbjct: 281 LKIDENQLMYLPDSIGGLISVEE 303
Score = 78.6 bits (185), Expect = 2e-14
Identities = 48/163 (29%), Positives = 82/163 (50%), Gaps = 1/163 (0%)
Frame = -2
Query: 731 CKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINL 552
C L+++P ++F+ L L L N++ LP L + L +L+L N L LP S+ NL
Sbjct: 32 CSLEQVPKEIFTFEKTLEELYLDANQIEELPKQLFNCQSLHKLSLPDNDLTTLPASIANL 91
Query: 551 KKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKIT 372
L L++S N +Q P +KN L V AS N + P L +L L L+ +
Sbjct: 92 INLRELDVSKNGIQEFPENIKNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLE 151
Query: 371 EIPYGMSELYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDEN 246
+P L ++ L L +N++ ++ + +++ +L+ L L N
Sbjct: 152 FLPANFGRLTKLQILELRENQLKMLPKTMNRLTQLERLDLGSN 194
Score = 63.3 bits (147), Expect = 9e-10
Identities = 38/121 (31%), Positives = 64/121 (52%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESL 561
I + +L +P + L V LD S N++ LP + +L +L+ D N LQ LP +
Sbjct: 283 IDENQLMYLPDSIGGLISV-EELDCSFNEVEALPSSIGQLTNLRTFAADHNYLQQLPPEI 341
Query: 560 INLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHN 381
+ K + VL + +N ++TLP + ++ LK + S+N+L+ P LQ L + LS N
Sbjct: 342 GSWKNITVLFLHSNKLETLPEEMGDMQKLKVINLSDNRLKNLPFSFTKLQQLTAMWLSDN 401
Query: 380 K 378
+
Sbjct: 402 Q 402
>AF276423-1|AAK69431.1| 1412|Homo sapiens densin-180-like protein
protein.
Length = 1412
Score = 91.1 bits (216), Expect = 4e-18
Identities = 56/193 (29%), Positives = 107/193 (55%), Gaps = 4/193 (2%)
Frame = -2
Query: 689 DVLRNLDLSKNKLSVLPDDLSKL-KHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFV 513
+ + LD S L +P ++ K L++L LD+N+++ LP+ L N + L L++ +N +
Sbjct: 22 ETVTTLDYSHCSLEQVPKEIFTFEKTLEELYLDANQIEELPKQLFNCQSLHKLSLPDNDL 81
Query: 512 QTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELY-VI 336
TLP + NL NL+++ S N +Q FP+ I + L +++ S N I+++P G S+L +
Sbjct: 82 TTLPASIANLINLRELDVSKNGIQEFPENIKNCKVLTIVEASVNPISKLPDGFSQLLNLT 141
Query: 335 ELNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIHTVSVDGNLFE-- 162
+L L+ + + + + +L+IL L EN L + + ++ R +++ + + N F
Sbjct: 142 QLYLNDAFLEFLPANFGRLTKLQILELRENQLKM--LPKTMNRLTQLERLDLGSNEFTEV 199
Query: 161 PKQLAXLEGYNEY 123
P+ L L G E+
Sbjct: 200 PEVLEQLSGLKEF 212
Score = 89.4 bits (212), Expect = 1e-17
Identities = 53/165 (32%), Positives = 89/165 (53%), Gaps = 1/165 (0%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
+++E+P +F+ C L L L N L+ LP ++ L +L++L++ N +Q PE++ N K
Sbjct: 57 QIEELPKQLFN-CQSLHKLSLPDNDLTTLPASIANLINLRELDVSKNGIQEFPENIKNCK 115
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITE 369
L ++ S N + LP L NL Q+Y ++ L+ P L L +L+L N++
Sbjct: 116 VLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPANFGRLTKLQILELRENQLKM 175
Query: 368 IPYGMSELYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDENCLS 237
+P M+ L +E L+L NE + + E L Q LK +D N L+
Sbjct: 176 LPKTMNRLTQLERLDLGSNEFTEVPEVLEQLSGLKEFWMDANRLT 220
Score = 87.8 bits (208), Expect = 4e-17
Identities = 50/152 (32%), Positives = 84/152 (55%), Gaps = 1/152 (0%)
Frame = -2
Query: 698 SLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNN 519
S C+ L++L LS N L LP+ + LK++ L +D N+L LP+S+ L +E L+ S N
Sbjct: 250 STCENLQDLLLSSNSLQQLPETIGSLKNITTLKIDENQLMYLPDSIGGLISVEELDCSFN 309
Query: 518 FVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYV 339
V+ LP + L NL+ A +N LQ P +I +++ VL L NK+ +P M ++
Sbjct: 310 EVEALPSSIGQLTNLRTFAADHNYLQQLPPEIGSWKNITVLFLHSNKLETLPEEMGDMQK 369
Query: 338 IE-LNLSQNEISLIGEDLHQAPRLKILRLDEN 246
++ +NLS N + + + +L + L +N
Sbjct: 370 LKVINLSDNRLKNLPFSFTKLQQLTAMWLSDN 401
Score = 81.8 bits (193), Expect = 2e-15
Identities = 53/200 (26%), Positives = 102/200 (51%), Gaps = 3/200 (1%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
+LK +P + L L LDL N+ + +P+ L +L LK+ +D+N+L +P + +LK
Sbjct: 172 QLKMLPKTMNRLTQ-LERLDLGSNEFTEVPEVLEQLSGLKEFWMDANRLTFIPGFIGSLK 230
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITE 369
+L L++S N ++ + + NL+ + S+N LQ P+ I L+++ L + N++
Sbjct: 231 QLTYLDVSKNNIEMVEEGISTCENLQDLLLSSNSLQQLPETIGSLKNITTLKIDENQLMY 290
Query: 368 IPYGMSELY-VIELNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIH 192
+P + L V EL+ S NE+ + + Q L+ D N L ++ P + I
Sbjct: 291 LPDSIGGLISVEELDCSFNEVEALPSSIGQLTNLRTFAADHN--YLQQLPPEIGSWKNIT 348
Query: 191 TVSVDGNLFE--PKQLAXLE 138
+ + N E P+++ ++
Sbjct: 349 VLFLHSNKLETLPEEMGDMQ 368
Score = 79.4 bits (187), Expect = 1e-14
Identities = 56/203 (27%), Positives = 103/203 (50%), Gaps = 3/203 (1%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKK 546
++E P ++ + C VL ++ S N +S LPD S+L +L QL L+ L+ LP + L K
Sbjct: 104 IQEFPENIKN-CKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPANFGRLTK 162
Query: 545 LEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEI 366
L++L + N ++ LP + L L+++ +N+ P+ + L L + N++T I
Sbjct: 163 LQILELRENQLKMLPKTMNRLTQLERLDLGSNEFTEVPEVLEQLSGLKEFWMDANRLTFI 222
Query: 365 PYGMSEL-YVIELNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIHT 189
P + L + L++S+N I ++ E + L+ L L N SL ++ ++ I T
Sbjct: 223 PGFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQDLLLSSN--SLQQLPETIGSLKNITT 280
Query: 188 VSVDGN--LFEPKQLAXLEGYNE 126
+ +D N ++ P + L E
Sbjct: 281 LKIDENQLMYLPDSIGGLISVEE 303
Score = 78.6 bits (185), Expect = 2e-14
Identities = 48/163 (29%), Positives = 82/163 (50%), Gaps = 1/163 (0%)
Frame = -2
Query: 731 CKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINL 552
C L+++P ++F+ L L L N++ LP L + L +L+L N L LP S+ NL
Sbjct: 32 CSLEQVPKEIFTFEKTLEELYLDANQIEELPKQLFNCQSLHKLSLPDNDLTTLPASIANL 91
Query: 551 KKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKIT 372
L L++S N +Q P +KN L V AS N + P L +L L L+ +
Sbjct: 92 INLRELDVSKNGIQEFPENIKNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLE 151
Query: 371 EIPYGMSELYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDEN 246
+P L ++ L L +N++ ++ + +++ +L+ L L N
Sbjct: 152 FLPANFGRLTKLQILELRENQLKMLPKTMNRLTQLERLDLGSN 194
Score = 63.3 bits (147), Expect = 9e-10
Identities = 38/121 (31%), Positives = 64/121 (52%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESL 561
I + +L +P + L V LD S N++ LP + +L +L+ D N LQ LP +
Sbjct: 283 IDENQLMYLPDSIGGLISV-EELDCSFNEVEALPSSIGQLTNLRTFAADHNYLQQLPPEI 341
Query: 560 INLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHN 381
+ K + VL + +N ++TLP + ++ LK + S+N+L+ P LQ L + LS N
Sbjct: 342 GSWKNITVLFLHSNKLETLPEEMGDMQKLKVINLSDNRLKNLPFSFTKLQQLTAMWLSDN 401
Query: 380 K 378
+
Sbjct: 402 Q 402
>AF263744-1|AAF77048.1| 1371|Homo sapiens erbb2-interacting protein
ERBIN protein.
Length = 1371
Score = 91.1 bits (216), Expect = 4e-18
Identities = 56/193 (29%), Positives = 107/193 (55%), Gaps = 4/193 (2%)
Frame = -2
Query: 689 DVLRNLDLSKNKLSVLPDDLSKL-KHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFV 513
+ + LD S L +P ++ K L++L LD+N+++ LP+ L N + L L++ +N +
Sbjct: 22 ETVTTLDYSHCSLEQVPKEIFTFEKTLEELYLDANQIEELPKQLFNCQSLHKLSLPDNDL 81
Query: 512 QTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELY-VI 336
TLP + NL NL+++ S N +Q FP+ I + L +++ S N I+++P G S+L +
Sbjct: 82 TTLPASIANLINLRELDVSKNGIQEFPENIKNCKVLTIVEASVNPISKLPDGFSQLLNLT 141
Query: 335 ELNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIHTVSVDGNLFE-- 162
+L L+ + + + + +L+IL L EN L + + ++ R +++ + + N F
Sbjct: 142 QLYLNDAFLEFLPANFGRLTKLQILELRENQLKM--LPKTMNRLTQLERLDLGSNEFTEV 199
Query: 161 PKQLAXLEGYNEY 123
P+ L L G E+
Sbjct: 200 PEVLEQLSGLKEF 212
Score = 89.4 bits (212), Expect = 1e-17
Identities = 53/165 (32%), Positives = 89/165 (53%), Gaps = 1/165 (0%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
+++E+P +F+ C L L L N L+ LP ++ L +L++L++ N +Q PE++ N K
Sbjct: 57 QIEELPKQLFN-CQSLHKLSLPDNDLTTLPASIANLINLRELDVSKNGIQEFPENIKNCK 115
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITE 369
L ++ S N + LP L NL Q+Y ++ L+ P L L +L+L N++
Sbjct: 116 VLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPANFGRLTKLQILELRENQLKM 175
Query: 368 IPYGMSELYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDENCLS 237
+P M+ L +E L+L NE + + E L Q LK +D N L+
Sbjct: 176 LPKTMNRLTQLERLDLGSNEFTEVPEVLEQLSGLKEFWMDANRLT 220
Score = 87.8 bits (208), Expect = 4e-17
Identities = 50/152 (32%), Positives = 84/152 (55%), Gaps = 1/152 (0%)
Frame = -2
Query: 698 SLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNN 519
S C+ L++L LS N L LP+ + LK++ L +D N+L LP+S+ L +E L+ S N
Sbjct: 250 STCENLQDLLLSSNSLQQLPETIGSLKNITTLKIDENQLMYLPDSIGGLISVEELDCSFN 309
Query: 518 FVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYV 339
V+ LP + L NL+ A +N LQ P +I +++ VL L NK+ +P M ++
Sbjct: 310 EVEALPSSIGQLTNLRTFAADHNYLQQLPPEIGSWKNITVLFLHSNKLETLPEEMGDMQK 369
Query: 338 IE-LNLSQNEISLIGEDLHQAPRLKILRLDEN 246
++ +NLS N + + + +L + L +N
Sbjct: 370 LKVINLSDNRLKNLPFSFTKLQQLTAMWLSDN 401
Score = 81.8 bits (193), Expect = 2e-15
Identities = 53/200 (26%), Positives = 102/200 (51%), Gaps = 3/200 (1%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
+LK +P + L L LDL N+ + +P+ L +L LK+ +D+N+L +P + +LK
Sbjct: 172 QLKMLPKTMNRLTQ-LERLDLGSNEFTEVPEVLEQLSGLKEFWMDANRLTFIPGFIGSLK 230
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITE 369
+L L++S N ++ + + NL+ + S+N LQ P+ I L+++ L + N++
Sbjct: 231 QLTYLDVSKNNIEMVEEGISTCENLQDLLLSSNSLQQLPETIGSLKNITTLKIDENQLMY 290
Query: 368 IPYGMSELY-VIELNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIH 192
+P + L V EL+ S NE+ + + Q L+ D N L ++ P + I
Sbjct: 291 LPDSIGGLISVEELDCSFNEVEALPSSIGQLTNLRTFAADHN--YLQQLPPEIGSWKNIT 348
Query: 191 TVSVDGNLFE--PKQLAXLE 138
+ + N E P+++ ++
Sbjct: 349 VLFLHSNKLETLPEEMGDMQ 368
Score = 79.4 bits (187), Expect = 1e-14
Identities = 56/203 (27%), Positives = 103/203 (50%), Gaps = 3/203 (1%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKK 546
++E P ++ + C VL ++ S N +S LPD S+L +L QL L+ L+ LP + L K
Sbjct: 104 IQEFPENIKN-CKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPANFGRLTK 162
Query: 545 LEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEI 366
L++L + N ++ LP + L L+++ +N+ P+ + L L + N++T I
Sbjct: 163 LQILELRENQLKMLPKTMNRLTQLERLDLGSNEFTEVPEVLEQLSGLKEFWMDANRLTFI 222
Query: 365 PYGMSEL-YVIELNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIHT 189
P + L + L++S+N I ++ E + L+ L L N SL ++ ++ I T
Sbjct: 223 PGFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQDLLLSSN--SLQQLPETIGSLKNITT 280
Query: 188 VSVDGN--LFEPKQLAXLEGYNE 126
+ +D N ++ P + L E
Sbjct: 281 LKIDENQLMYLPDSIGGLISVEE 303
Score = 78.6 bits (185), Expect = 2e-14
Identities = 48/163 (29%), Positives = 82/163 (50%), Gaps = 1/163 (0%)
Frame = -2
Query: 731 CKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINL 552
C L+++P ++F+ L L L N++ LP L + L +L+L N L LP S+ NL
Sbjct: 32 CSLEQVPKEIFTFEKTLEELYLDANQIEELPKQLFNCQSLHKLSLPDNDLTTLPASIANL 91
Query: 551 KKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKIT 372
L L++S N +Q P +KN L V AS N + P L +L L L+ +
Sbjct: 92 INLRELDVSKNGIQEFPENIKNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLE 151
Query: 371 EIPYGMSELYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDEN 246
+P L ++ L L +N++ ++ + +++ +L+ L L N
Sbjct: 152 FLPANFGRLTKLQILELRENQLKMLPKTMNRLTQLERLDLGSN 194
Score = 63.3 bits (147), Expect = 9e-10
Identities = 38/121 (31%), Positives = 64/121 (52%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESL 561
I + +L +P + L V LD S N++ LP + +L +L+ D N LQ LP +
Sbjct: 283 IDENQLMYLPDSIGGLISV-EELDCSFNEVEALPSSIGQLTNLRTFAADHNYLQQLPPEI 341
Query: 560 INLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHN 381
+ K + VL + +N ++TLP + ++ LK + S+N+L+ P LQ L + LS N
Sbjct: 342 GSWKNITVLFLHSNKLETLPEEMGDMQKLKVINLSDNRLKNLPFSFTKLQQLTAMWLSDN 401
Query: 380 K 378
+
Sbjct: 402 Q 402
>AB033051-1|BAA86539.2| 1371|Homo sapiens KIAA1225 protein protein.
Length = 1371
Score = 91.1 bits (216), Expect = 4e-18
Identities = 56/193 (29%), Positives = 107/193 (55%), Gaps = 4/193 (2%)
Frame = -2
Query: 689 DVLRNLDLSKNKLSVLPDDLSKL-KHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFV 513
+ + LD S L +P ++ K L++L LD+N+++ LP+ L N + L L++ +N +
Sbjct: 22 ETVTTLDYSHCSLEQVPKEIFTFEKTLEELYLDANQIEELPKQLFNCQSLHKLSLPDNDL 81
Query: 512 QTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELY-VI 336
TLP + NL NL+++ S N +Q FP+ I + L +++ S N I+++P G S+L +
Sbjct: 82 TTLPASIANLINLRELDVSKNGIQEFPENIKNCKVLTIVEASVNPISKLPDGFSQLLNLT 141
Query: 335 ELNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIHTVSVDGNLFE-- 162
+L L+ + + + + +L+IL L EN L + + ++ R +++ + + N F
Sbjct: 142 QLYLNDAFLEFLPANFGRLTKLQILELRENQLKM--LPKTMNRLTQLERLDLGSNEFTEV 199
Query: 161 PKQLAXLEGYNEY 123
P+ L L G E+
Sbjct: 200 PEVLEQLSGLKEF 212
Score = 89.4 bits (212), Expect = 1e-17
Identities = 53/165 (32%), Positives = 89/165 (53%), Gaps = 1/165 (0%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
+++E+P +F+ C L L L N L+ LP ++ L +L++L++ N +Q PE++ N K
Sbjct: 57 QIEELPKQLFN-CQSLHKLSLPDNDLTTLPASIANLINLRELDVSKNGIQEFPENIKNCK 115
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITE 369
L ++ S N + LP L NL Q+Y ++ L+ P L L +L+L N++
Sbjct: 116 VLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPANFGRLTKLQILELRENQLKM 175
Query: 368 IPYGMSELYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDENCLS 237
+P M+ L +E L+L NE + + E L Q LK +D N L+
Sbjct: 176 LPKTMNRLTQLERLDLGSNEFTEVPEVLEQLSGLKEFWMDANRLT 220
Score = 87.8 bits (208), Expect = 4e-17
Identities = 50/152 (32%), Positives = 84/152 (55%), Gaps = 1/152 (0%)
Frame = -2
Query: 698 SLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNN 519
S C+ L++L LS N L LP+ + LK++ L +D N+L LP+S+ L +E L+ S N
Sbjct: 250 STCENLQDLLLSSNSLQQLPETIGSLKNITTLKIDENQLMYLPDSIGGLISVEELDCSFN 309
Query: 518 FVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYV 339
V+ LP + L NL+ A +N LQ P +I +++ VL L NK+ +P M ++
Sbjct: 310 EVEALPSSIGQLTNLRTFAADHNYLQQLPPEIGSWKNITVLFLHSNKLETLPEEMGDMQK 369
Query: 338 IE-LNLSQNEISLIGEDLHQAPRLKILRLDEN 246
++ +NLS N + + + +L + L +N
Sbjct: 370 LKVINLSDNRLKNLPFSFTKLQQLTAMWLSDN 401
Score = 81.8 bits (193), Expect = 2e-15
Identities = 53/200 (26%), Positives = 102/200 (51%), Gaps = 3/200 (1%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
+LK +P + L L LDL N+ + +P+ L +L LK+ +D+N+L +P + +LK
Sbjct: 172 QLKMLPKTMNRLTQ-LERLDLGSNEFTEVPEVLEQLSGLKEFWMDANRLTFIPGFIGSLK 230
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITE 369
+L L++S N ++ + + NL+ + S+N LQ P+ I L+++ L + N++
Sbjct: 231 QLTYLDVSKNNIEMVEEGISTCENLQDLLLSSNSLQQLPETIGSLKNITTLKIDENQLMY 290
Query: 368 IPYGMSELY-VIELNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIH 192
+P + L V EL+ S NE+ + + Q L+ D N L ++ P + I
Sbjct: 291 LPDSIGGLISVEELDCSFNEVEALPSSIGQLTNLRTFAADHN--YLQQLPPEIGSWKNIT 348
Query: 191 TVSVDGNLFE--PKQLAXLE 138
+ + N E P+++ ++
Sbjct: 349 VLFLHSNKLETLPEEMGDMQ 368
Score = 79.4 bits (187), Expect = 1e-14
Identities = 56/203 (27%), Positives = 103/203 (50%), Gaps = 3/203 (1%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKK 546
++E P ++ + C VL ++ S N +S LPD S+L +L QL L+ L+ LP + L K
Sbjct: 104 IQEFPENIKN-CKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPANFGRLTK 162
Query: 545 LEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEI 366
L++L + N ++ LP + L L+++ +N+ P+ + L L + N++T I
Sbjct: 163 LQILELRENQLKMLPKTMNRLTQLERLDLGSNEFTEVPEVLEQLSGLKEFWMDANRLTFI 222
Query: 365 PYGMSEL-YVIELNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIHT 189
P + L + L++S+N I ++ E + L+ L L N SL ++ ++ I T
Sbjct: 223 PGFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQDLLLSSN--SLQQLPETIGSLKNITT 280
Query: 188 VSVDGN--LFEPKQLAXLEGYNE 126
+ +D N ++ P + L E
Sbjct: 281 LKIDENQLMYLPDSIGGLISVEE 303
Score = 78.6 bits (185), Expect = 2e-14
Identities = 48/163 (29%), Positives = 82/163 (50%), Gaps = 1/163 (0%)
Frame = -2
Query: 731 CKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINL 552
C L+++P ++F+ L L L N++ LP L + L +L+L N L LP S+ NL
Sbjct: 32 CSLEQVPKEIFTFEKTLEELYLDANQIEELPKQLFNCQSLHKLSLPDNDLTTLPASIANL 91
Query: 551 KKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKIT 372
L L++S N +Q P +KN L V AS N + P L +L L L+ +
Sbjct: 92 INLRELDVSKNGIQEFPENIKNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLE 151
Query: 371 EIPYGMSELYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDEN 246
+P L ++ L L +N++ ++ + +++ +L+ L L N
Sbjct: 152 FLPANFGRLTKLQILELRENQLKMLPKTMNRLTQLERLDLGSN 194
Score = 63.3 bits (147), Expect = 9e-10
Identities = 38/121 (31%), Positives = 64/121 (52%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESL 561
I + +L +P + L V LD S N++ LP + +L +L+ D N LQ LP +
Sbjct: 283 IDENQLMYLPDSIGGLISV-EELDCSFNEVEALPSSIGQLTNLRTFAADHNYLQQLPPEI 341
Query: 560 INLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHN 381
+ K + VL + +N ++TLP + ++ LK + S+N+L+ P LQ L + LS N
Sbjct: 342 GSWKNITVLFLHSNKLETLPEEMGDMQKLKVINLSDNRLKNLPFSFTKLQQLTAMWLSDN 401
Query: 380 K 378
+
Sbjct: 402 Q 402
>AB016816-1|BAA74737.1| 1052|Homo sapiens MASL1 protein.
Length = 1052
Score = 90.6 bits (215), Expect = 5e-18
Identities = 55/162 (33%), Positives = 88/162 (54%), Gaps = 1/162 (0%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
+L + +V S LR L+LS N+L LP L L HL++L++ N+L LP+SL L
Sbjct: 122 RLTALGAEVVSALRELRKLNLSHNQLPALPAQLGALAHLEELDVSFNRLAHLPDSLSCLS 181
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITE 369
+L L++ +N + P L L L+++ S+N+L+ P+ I L++L +L LS ++
Sbjct: 182 RLRTLDVDHNQLTAFPRQLLQLVALEELDVSSNRLRGLPEDISALRALKILWLSGAELGT 241
Query: 368 IPYGMSELYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDEN 246
+P G EL +E L L N + + RLK+L L N
Sbjct: 242 LPAGFCELASLESLMLDNNGLQALPAQFSCLQRLKMLNLSSN 283
Score = 90.6 bits (215), Expect = 5e-18
Identities = 58/162 (35%), Positives = 89/162 (54%), Gaps = 1/162 (0%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
+L +P D S LR LD+ N+L+ P L +L L++L++ SN+L+ LPE + L+
Sbjct: 169 RLAHLP-DSLSCLSRLRTLDVDHNQLTAFPRQLLQLVALEELDVSSNRLRGLPEDISALR 227
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITE 369
L++L +S + TLP L +L+ + NN LQA P Q LQ L +L+LS N E
Sbjct: 228 ALKILWLSGAELGTLPAGFCELASLESLMLDNNGLQALPAQFSCLQRLKMLNLSSNLFEE 287
Query: 368 IPYGMSELYVI-ELNLSQNEISLIGEDLHQAPRLKILRLDEN 246
P + L + EL LS+N+++ + + RL L LD N
Sbjct: 288 FPAALLPLAGLEELYLSRNQLTSVPSLISGLGRLLTLWLDNN 329
Score = 90.6 bits (215), Expect = 5e-18
Identities = 57/168 (33%), Positives = 96/168 (57%), Gaps = 1/168 (0%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESL 561
++ +L+ +P D+ +L L+ L LS +L LP +L L+ L LD+N LQALP
Sbjct: 211 VSSNRLRGLPEDISAL-RALKILWLSGAELGTLPAGFCELASLESLMLDNNGLQALPAQF 269
Query: 560 INLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHN 381
L++L++LN+S+N + P L L L+++Y S N+L + P I GL L L L +N
Sbjct: 270 SCLQRLKMLNLSSNLFEEFPAALLPLAGLEELYLSRNQLTSVPSLISGLGRLLTLWLDNN 329
Query: 380 KITEIPYGMSELYVI-ELNLSQNEISLIGEDLHQAPRLKILRLDENCL 240
+I +P + EL + EL L N+I+++ + Q R+ + ++ +N L
Sbjct: 330 RIRYLPDSIVELTGLEELVLQGNQIAVLPDHFGQLSRVGLWKIKDNPL 377
Score = 59.7 bits (138), Expect = 1e-08
Identities = 42/135 (31%), Positives = 77/135 (57%), Gaps = 4/135 (2%)
Frame = -2
Query: 629 SKLKHLKQLNLDSNKLQALPESLIN-LKKLEVLNISNNFVQTLPVCLKNL-NNLKQVYAS 456
+ L ++ LNL +N L+ +PE L + L L VL + N LP + L ++L ++ S
Sbjct: 60 ANLGDIEALNLGNNGLEEVPEGLGSALGSLRVLVLRRNRFARLPPAVAELGHHLTELDVS 119
Query: 455 NNKLQAFPKQIL-GLQSLDVLDLSHNKITEIPYGMSEL-YVIELNLSQNEISLIGEDLHQ 282
+N+L A +++ L+ L L+LSHN++ +P + L ++ EL++S N ++ + + L
Sbjct: 120 HNRLTALGAEVVSALRELRKLNLSHNQLPALPAQLGALAHLEELDVSFNRLAHLPDSLSC 179
Query: 281 APRLKILRLDENCLS 237
RL+ L +D N L+
Sbjct: 180 LSRLRTLDVDHNQLT 194
Score = 52.0 bits (119), Expect = 2e-06
Identities = 49/167 (29%), Positives = 81/167 (48%), Gaps = 10/167 (5%)
Frame = -2
Query: 596 DSNKLQALPESLI--NLKKLEVLNISNNFVQTLPVCLKN-LNNLKQVYASNNKLQAFPKQ 426
D+ + A P+ ++ NL +E LN+ NN ++ +P L + L +L+ + N+ P
Sbjct: 46 DALESPASPQLVLPANLGDIEALNLGNNGLEEVPEGLGSALGSLRVLVLRRNRFARLPPA 105
Query: 425 ILGL-QSLDVLDLSHNKIT----EIPYGMSELYVIELNLSQNEISLIGEDLHQAPRLKIL 261
+ L L LD+SHN++T E+ + EL +LNLS N++ + L L+
Sbjct: 106 VAELGHHLTELDVSHNRLTALGAEVVSALRELR--KLNLSHNQLPALPAQLGALAHLE-- 161
Query: 260 RLDENCLSLDEIKPSLLRDSKIHTVSVDGNLFE--PKQLAXLEGYNE 126
LD + L + SL S++ T+ VD N P+QL L E
Sbjct: 162 ELDVSFNRLAHLPDSLSCLSRLRTLDVDHNQLTAFPRQLLQLVALEE 208
>AL391728-2|CAH73692.1| 1495|Homo sapiens leucine rich repeat
containing 7 protein.
Length = 1495
Score = 89.8 bits (213), Expect = 9e-18
Identities = 61/193 (31%), Positives = 101/193 (52%), Gaps = 9/193 (4%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
+++E+P +F+ C LR L + N LS LP ++ L +LK+L++ N +Q PE++ K
Sbjct: 62 QIEELPKQLFN-CQALRKLSIPDNDLSNLPTTIASLVNLKELDISKNGVQEFPENIKCCK 120
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITE 369
L ++ S N + LP L NL Q+Y ++ L+ P L L +L+L N +
Sbjct: 121 CLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRENHLKT 180
Query: 368 IPYGMSELYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDENCL-----SLDEIKPSLLR 207
+P M +L +E L+L NE + E L Q L+ L +D N L S+ ++K +
Sbjct: 181 LPKSMHKLAQLERLDLGNNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLKMLVYL 240
Query: 206 D---SKIHTVSVD 177
D ++I TV +D
Sbjct: 241 DMSKNRIETVDMD 253
Score = 87.0 bits (206), Expect = 6e-17
Identities = 52/163 (31%), Positives = 89/163 (54%), Gaps = 1/163 (0%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKK 546
LK +P + L L LDL N+ LP+ L ++++L++L +D+N LQ LP S+ LK
Sbjct: 178 LKTLPKSMHKLAQ-LERLDLGNNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLKM 236
Query: 545 LEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEI 366
L L++S N ++T+ + + L+ + S+N LQ P I L+ L L + N++T +
Sbjct: 237 LVYLDMSKNRIETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTML 296
Query: 365 PYGMSELYVI-ELNLSQNEISLIGEDLHQAPRLKILRLDENCL 240
P + L ++ E + S NE+ + + L+ L +DEN L
Sbjct: 297 PNTIGNLSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENFL 339
Score = 87.0 bits (206), Expect = 6e-17
Identities = 50/146 (34%), Positives = 84/146 (57%), Gaps = 1/146 (0%)
Frame = -2
Query: 674 LDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTLPVC 495
LD+SKN++ + D+S + L+ L L SN LQ LP+S+ LKKL L + +N + LP
Sbjct: 240 LDMSKNRIETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNT 299
Query: 494 LKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSEL-YVIELNLSQ 318
+ NL+ L++ S N+L++ P I L SL L + N + E+P + V ++L
Sbjct: 300 IGNLSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRS 359
Query: 317 NEISLIGEDLHQAPRLKILRLDENCL 240
N++ + E++ Q +L++L L +N L
Sbjct: 360 NKLEFLPEEIGQMQKLRVLNLSDNRL 385
Score = 83.0 bits (196), Expect = 1e-15
Identities = 49/162 (30%), Positives = 87/162 (53%), Gaps = 1/162 (0%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
+++ + +D+ S C+ L +L LS N L LPD + LK L L +D N+L LP ++ NL
Sbjct: 246 RIETVDMDI-SGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIGNLS 304
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITE 369
LE + S N +++LP + L++L+ + N L P++I +++ V+ L NK+
Sbjct: 305 LLEEFDCSCNELESLPSTIGYLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLEF 364
Query: 368 IPYGMSELYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDEN 246
+P + ++ + LNLS N + + + L L L +N
Sbjct: 365 LPEEIGQMQKLRVLNLSDNRLKNLPFSFTKLKELAALWLSDN 406
Score = 81.8 bits (193), Expect = 2e-15
Identities = 53/165 (32%), Positives = 88/165 (53%), Gaps = 1/165 (0%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKK 546
+ ++P D F+ L L L+ L LP + +L L+ L L N L+ LP+S+ L +
Sbjct: 132 ISKLP-DGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRENHLKTLPKSMHKLAQ 190
Query: 545 LEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEI 366
LE L++ NN LP L + NL++++ NN LQ P I L+ L LD+S N+I +
Sbjct: 191 LERLDLGNNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIETV 250
Query: 365 PYGMSELYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDENCLSL 234
+S +E L LS N + + + + +L L++D+N L++
Sbjct: 251 DMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTM 295
Score = 81.0 bits (191), Expect = 4e-15
Identities = 49/177 (27%), Positives = 99/177 (55%), Gaps = 2/177 (1%)
Frame = -2
Query: 689 DVLRNLDLSKNKLSVLPDDLSKLKH-LKQLNLDSNKLQALPESLINLKKLEVLNISNNFV 513
+++ LD S L +P ++ + L++L LD+N+++ LP+ L N + L L+I +N +
Sbjct: 27 EIISVLDYSHCSLQQVPKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDL 86
Query: 512 QTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELY-VI 336
LP + +L NLK++ S N +Q FP+ I + L +++ S N I+++P G ++L +
Sbjct: 87 SNLPTTIASLVNLKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLT 146
Query: 335 ELNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIHTVSVDGNLF 165
+L L+ + + + + +L+IL L EN L + S+ + +++ + + N F
Sbjct: 147 QLYLNDAFLEFLPANFGRLVKLRILELREN--HLKTLPKSMHKLAQLERLDLGNNEF 201
Score = 60.5 bits (140), Expect = 6e-09
Identities = 30/82 (36%), Positives = 51/82 (62%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTL 504
LR L + +N L LP ++ K++ ++L SNKL+ LPE + ++KL VLN+S+N ++ L
Sbjct: 329 LRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLEFLPEEIGQMQKLRVLNLSDNRLKNL 388
Query: 503 PVCLKNLNNLKQVYASNNKLQA 438
P L L ++ S+N+ +A
Sbjct: 389 PFSFTKLKELAALWLSDNQSKA 410
Score = 33.9 bits (74), Expect = 0.62
Identities = 21/52 (40%), Positives = 31/52 (59%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQAL 573
KL+ +P ++ + LR L+LS N+L LP +KLK L L L N+ +AL
Sbjct: 361 KLEFLPEEIGQM-QKLRVLNLSDNRLKNLPFSFTKLKELAALWLSDNQSKAL 411
>AL391728-1|CAH73691.1| 1537|Homo sapiens leucine rich repeat
containing 7 protein.
Length = 1537
Score = 89.8 bits (213), Expect = 9e-18
Identities = 61/193 (31%), Positives = 101/193 (52%), Gaps = 9/193 (4%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
+++E+P +F+ C LR L + N LS LP ++ L +LK+L++ N +Q PE++ K
Sbjct: 57 QIEELPKQLFN-CQALRKLSIPDNDLSNLPTTIASLVNLKELDISKNGVQEFPENIKCCK 115
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITE 369
L ++ S N + LP L NL Q+Y ++ L+ P L L +L+L N +
Sbjct: 116 CLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRENHLKT 175
Query: 368 IPYGMSELYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDENCL-----SLDEIKPSLLR 207
+P M +L +E L+L NE + E L Q L+ L +D N L S+ ++K +
Sbjct: 176 LPKSMHKLAQLERLDLGNNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLKMLVYL 235
Query: 206 D---SKIHTVSVD 177
D ++I TV +D
Sbjct: 236 DMSKNRIETVDMD 248
Score = 87.0 bits (206), Expect = 6e-17
Identities = 52/163 (31%), Positives = 89/163 (54%), Gaps = 1/163 (0%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKK 546
LK +P + L L LDL N+ LP+ L ++++L++L +D+N LQ LP S+ LK
Sbjct: 173 LKTLPKSMHKLAQ-LERLDLGNNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLKM 231
Query: 545 LEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEI 366
L L++S N ++T+ + + L+ + S+N LQ P I L+ L L + N++T +
Sbjct: 232 LVYLDMSKNRIETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTML 291
Query: 365 PYGMSELYVI-ELNLSQNEISLIGEDLHQAPRLKILRLDENCL 240
P + L ++ E + S NE+ + + L+ L +DEN L
Sbjct: 292 PNTIGNLSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENFL 334
Score = 87.0 bits (206), Expect = 6e-17
Identities = 50/146 (34%), Positives = 84/146 (57%), Gaps = 1/146 (0%)
Frame = -2
Query: 674 LDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTLPVC 495
LD+SKN++ + D+S + L+ L L SN LQ LP+S+ LKKL L + +N + LP
Sbjct: 235 LDMSKNRIETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNT 294
Query: 494 LKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSEL-YVIELNLSQ 318
+ NL+ L++ S N+L++ P I L SL L + N + E+P + V ++L
Sbjct: 295 IGNLSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRS 354
Query: 317 NEISLIGEDLHQAPRLKILRLDENCL 240
N++ + E++ Q +L++L L +N L
Sbjct: 355 NKLEFLPEEIGQMQKLRVLNLSDNRL 380
Score = 83.0 bits (196), Expect = 1e-15
Identities = 49/162 (30%), Positives = 87/162 (53%), Gaps = 1/162 (0%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
+++ + +D+ S C+ L +L LS N L LPD + LK L L +D N+L LP ++ NL
Sbjct: 241 RIETVDMDI-SGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIGNLS 299
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITE 369
LE + S N +++LP + L++L+ + N L P++I +++ V+ L NK+
Sbjct: 300 LLEEFDCSCNELESLPSTIGYLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLEF 359
Query: 368 IPYGMSELYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDEN 246
+P + ++ + LNLS N + + + L L L +N
Sbjct: 360 LPEEIGQMQKLRVLNLSDNRLKNLPFSFTKLKELAALWLSDN 401
Score = 81.8 bits (193), Expect = 2e-15
Identities = 53/165 (32%), Positives = 88/165 (53%), Gaps = 1/165 (0%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKK 546
+ ++P D F+ L L L+ L LP + +L L+ L L N L+ LP+S+ L +
Sbjct: 127 ISKLP-DGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRENHLKTLPKSMHKLAQ 185
Query: 545 LEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEI 366
LE L++ NN LP L + NL++++ NN LQ P I L+ L LD+S N+I +
Sbjct: 186 LERLDLGNNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIETV 245
Query: 365 PYGMSELYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDENCLSL 234
+S +E L LS N + + + + +L L++D+N L++
Sbjct: 246 DMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTM 290
Score = 81.0 bits (191), Expect = 4e-15
Identities = 49/177 (27%), Positives = 99/177 (55%), Gaps = 2/177 (1%)
Frame = -2
Query: 689 DVLRNLDLSKNKLSVLPDDLSKLKH-LKQLNLDSNKLQALPESLINLKKLEVLNISNNFV 513
+++ LD S L +P ++ + L++L LD+N+++ LP+ L N + L L+I +N +
Sbjct: 22 EIISVLDYSHCSLQQVPKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDL 81
Query: 512 QTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELY-VI 336
LP + +L NLK++ S N +Q FP+ I + L +++ S N I+++P G ++L +
Sbjct: 82 SNLPTTIASLVNLKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLT 141
Query: 335 ELNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIHTVSVDGNLF 165
+L L+ + + + + +L+IL L EN L + S+ + +++ + + N F
Sbjct: 142 QLYLNDAFLEFLPANFGRLVKLRILELREN--HLKTLPKSMHKLAQLERLDLGNNEF 196
Score = 60.5 bits (140), Expect = 6e-09
Identities = 30/82 (36%), Positives = 51/82 (62%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTL 504
LR L + +N L LP ++ K++ ++L SNKL+ LPE + ++KL VLN+S+N ++ L
Sbjct: 324 LRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLEFLPEEIGQMQKLRVLNLSDNRLKNL 383
Query: 503 PVCLKNLNNLKQVYASNNKLQA 438
P L L ++ S+N+ +A
Sbjct: 384 PFSFTKLKELAALWLSDNQSKA 405
Score = 33.9 bits (74), Expect = 0.62
Identities = 21/52 (40%), Positives = 31/52 (59%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQAL 573
KL+ +P ++ + LR L+LS N+L LP +KLK L L L N+ +AL
Sbjct: 356 KLEFLPEEIGQM-QKLRVLNLSDNRLKNLPFSFTKLKELAALWLSDNQSKAL 406
>AL359412-2|CAH74019.1| 1495|Homo sapiens leucine rich repeat
containing 7 protein.
Length = 1495
Score = 89.8 bits (213), Expect = 9e-18
Identities = 61/193 (31%), Positives = 101/193 (52%), Gaps = 9/193 (4%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
+++E+P +F+ C LR L + N LS LP ++ L +LK+L++ N +Q PE++ K
Sbjct: 62 QIEELPKQLFN-CQALRKLSIPDNDLSNLPTTIASLVNLKELDISKNGVQEFPENIKCCK 120
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITE 369
L ++ S N + LP L NL Q+Y ++ L+ P L L +L+L N +
Sbjct: 121 CLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRENHLKT 180
Query: 368 IPYGMSELYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDENCL-----SLDEIKPSLLR 207
+P M +L +E L+L NE + E L Q L+ L +D N L S+ ++K +
Sbjct: 181 LPKSMHKLAQLERLDLGNNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLKMLVYL 240
Query: 206 D---SKIHTVSVD 177
D ++I TV +D
Sbjct: 241 DMSKNRIETVDMD 253
Score = 87.0 bits (206), Expect = 6e-17
Identities = 52/163 (31%), Positives = 89/163 (54%), Gaps = 1/163 (0%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKK 546
LK +P + L L LDL N+ LP+ L ++++L++L +D+N LQ LP S+ LK
Sbjct: 178 LKTLPKSMHKLAQ-LERLDLGNNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLKM 236
Query: 545 LEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEI 366
L L++S N ++T+ + + L+ + S+N LQ P I L+ L L + N++T +
Sbjct: 237 LVYLDMSKNRIETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTML 296
Query: 365 PYGMSELYVI-ELNLSQNEISLIGEDLHQAPRLKILRLDENCL 240
P + L ++ E + S NE+ + + L+ L +DEN L
Sbjct: 297 PNTIGNLSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENFL 339
Score = 87.0 bits (206), Expect = 6e-17
Identities = 50/146 (34%), Positives = 84/146 (57%), Gaps = 1/146 (0%)
Frame = -2
Query: 674 LDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTLPVC 495
LD+SKN++ + D+S + L+ L L SN LQ LP+S+ LKKL L + +N + LP
Sbjct: 240 LDMSKNRIETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNT 299
Query: 494 LKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSEL-YVIELNLSQ 318
+ NL+ L++ S N+L++ P I L SL L + N + E+P + V ++L
Sbjct: 300 IGNLSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRS 359
Query: 317 NEISLIGEDLHQAPRLKILRLDENCL 240
N++ + E++ Q +L++L L +N L
Sbjct: 360 NKLEFLPEEIGQMQKLRVLNLSDNRL 385
Score = 83.0 bits (196), Expect = 1e-15
Identities = 49/162 (30%), Positives = 87/162 (53%), Gaps = 1/162 (0%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
+++ + +D+ S C+ L +L LS N L LPD + LK L L +D N+L LP ++ NL
Sbjct: 246 RIETVDMDI-SGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIGNLS 304
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITE 369
LE + S N +++LP + L++L+ + N L P++I +++ V+ L NK+
Sbjct: 305 LLEEFDCSCNELESLPSTIGYLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLEF 364
Query: 368 IPYGMSELYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDEN 246
+P + ++ + LNLS N + + + L L L +N
Sbjct: 365 LPEEIGQMQKLRVLNLSDNRLKNLPFSFTKLKELAALWLSDN 406
Score = 81.8 bits (193), Expect = 2e-15
Identities = 53/165 (32%), Positives = 88/165 (53%), Gaps = 1/165 (0%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKK 546
+ ++P D F+ L L L+ L LP + +L L+ L L N L+ LP+S+ L +
Sbjct: 132 ISKLP-DGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRENHLKTLPKSMHKLAQ 190
Query: 545 LEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEI 366
LE L++ NN LP L + NL++++ NN LQ P I L+ L LD+S N+I +
Sbjct: 191 LERLDLGNNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIETV 250
Query: 365 PYGMSELYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDENCLSL 234
+S +E L LS N + + + + +L L++D+N L++
Sbjct: 251 DMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTM 295
Score = 81.0 bits (191), Expect = 4e-15
Identities = 49/177 (27%), Positives = 99/177 (55%), Gaps = 2/177 (1%)
Frame = -2
Query: 689 DVLRNLDLSKNKLSVLPDDLSKLKH-LKQLNLDSNKLQALPESLINLKKLEVLNISNNFV 513
+++ LD S L +P ++ + L++L LD+N+++ LP+ L N + L L+I +N +
Sbjct: 27 EIISVLDYSHCSLQQVPKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDL 86
Query: 512 QTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELY-VI 336
LP + +L NLK++ S N +Q FP+ I + L +++ S N I+++P G ++L +
Sbjct: 87 SNLPTTIASLVNLKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLT 146
Query: 335 ELNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIHTVSVDGNLF 165
+L L+ + + + + +L+IL L EN L + S+ + +++ + + N F
Sbjct: 147 QLYLNDAFLEFLPANFGRLVKLRILELREN--HLKTLPKSMHKLAQLERLDLGNNEF 201
Score = 60.5 bits (140), Expect = 6e-09
Identities = 30/82 (36%), Positives = 51/82 (62%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTL 504
LR L + +N L LP ++ K++ ++L SNKL+ LPE + ++KL VLN+S+N ++ L
Sbjct: 329 LRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLEFLPEEIGQMQKLRVLNLSDNRLKNL 388
Query: 503 PVCLKNLNNLKQVYASNNKLQA 438
P L L ++ S+N+ +A
Sbjct: 389 PFSFTKLKELAALWLSDNQSKA 410
Score = 33.9 bits (74), Expect = 0.62
Identities = 21/52 (40%), Positives = 31/52 (59%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQAL 573
KL+ +P ++ + LR L+LS N+L LP +KLK L L L N+ +AL
Sbjct: 361 KLEFLPEEIGQM-QKLRVLNLSDNRLKNLPFSFTKLKELAALWLSDNQSKAL 411
>AL359412-1|CAH74018.1| 1537|Homo sapiens leucine rich repeat
containing 7 protein.
Length = 1537
Score = 89.8 bits (213), Expect = 9e-18
Identities = 61/193 (31%), Positives = 101/193 (52%), Gaps = 9/193 (4%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
+++E+P +F+ C LR L + N LS LP ++ L +LK+L++ N +Q PE++ K
Sbjct: 57 QIEELPKQLFN-CQALRKLSIPDNDLSNLPTTIASLVNLKELDISKNGVQEFPENIKCCK 115
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITE 369
L ++ S N + LP L NL Q+Y ++ L+ P L L +L+L N +
Sbjct: 116 CLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRENHLKT 175
Query: 368 IPYGMSELYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDENCL-----SLDEIKPSLLR 207
+P M +L +E L+L NE + E L Q L+ L +D N L S+ ++K +
Sbjct: 176 LPKSMHKLAQLERLDLGNNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLKMLVYL 235
Query: 206 D---SKIHTVSVD 177
D ++I TV +D
Sbjct: 236 DMSKNRIETVDMD 248
Score = 87.0 bits (206), Expect = 6e-17
Identities = 52/163 (31%), Positives = 89/163 (54%), Gaps = 1/163 (0%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKK 546
LK +P + L L LDL N+ LP+ L ++++L++L +D+N LQ LP S+ LK
Sbjct: 173 LKTLPKSMHKLAQ-LERLDLGNNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLKM 231
Query: 545 LEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEI 366
L L++S N ++T+ + + L+ + S+N LQ P I L+ L L + N++T +
Sbjct: 232 LVYLDMSKNRIETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTML 291
Query: 365 PYGMSELYVI-ELNLSQNEISLIGEDLHQAPRLKILRLDENCL 240
P + L ++ E + S NE+ + + L+ L +DEN L
Sbjct: 292 PNTIGNLSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENFL 334
Score = 87.0 bits (206), Expect = 6e-17
Identities = 50/146 (34%), Positives = 84/146 (57%), Gaps = 1/146 (0%)
Frame = -2
Query: 674 LDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTLPVC 495
LD+SKN++ + D+S + L+ L L SN LQ LP+S+ LKKL L + +N + LP
Sbjct: 235 LDMSKNRIETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNT 294
Query: 494 LKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSEL-YVIELNLSQ 318
+ NL+ L++ S N+L++ P I L SL L + N + E+P + V ++L
Sbjct: 295 IGNLSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRS 354
Query: 317 NEISLIGEDLHQAPRLKILRLDENCL 240
N++ + E++ Q +L++L L +N L
Sbjct: 355 NKLEFLPEEIGQMQKLRVLNLSDNRL 380
Score = 83.0 bits (196), Expect = 1e-15
Identities = 49/162 (30%), Positives = 87/162 (53%), Gaps = 1/162 (0%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
+++ + +D+ S C+ L +L LS N L LPD + LK L L +D N+L LP ++ NL
Sbjct: 241 RIETVDMDI-SGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIGNLS 299
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITE 369
LE + S N +++LP + L++L+ + N L P++I +++ V+ L NK+
Sbjct: 300 LLEEFDCSCNELESLPSTIGYLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLEF 359
Query: 368 IPYGMSELYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDEN 246
+P + ++ + LNLS N + + + L L L +N
Sbjct: 360 LPEEIGQMQKLRVLNLSDNRLKNLPFSFTKLKELAALWLSDN 401
Score = 81.8 bits (193), Expect = 2e-15
Identities = 53/165 (32%), Positives = 88/165 (53%), Gaps = 1/165 (0%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKK 546
+ ++P D F+ L L L+ L LP + +L L+ L L N L+ LP+S+ L +
Sbjct: 127 ISKLP-DGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRENHLKTLPKSMHKLAQ 185
Query: 545 LEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEI 366
LE L++ NN LP L + NL++++ NN LQ P I L+ L LD+S N+I +
Sbjct: 186 LERLDLGNNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIETV 245
Query: 365 PYGMSELYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDENCLSL 234
+S +E L LS N + + + + +L L++D+N L++
Sbjct: 246 DMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTM 290
Score = 81.0 bits (191), Expect = 4e-15
Identities = 49/177 (27%), Positives = 99/177 (55%), Gaps = 2/177 (1%)
Frame = -2
Query: 689 DVLRNLDLSKNKLSVLPDDLSKLKH-LKQLNLDSNKLQALPESLINLKKLEVLNISNNFV 513
+++ LD S L +P ++ + L++L LD+N+++ LP+ L N + L L+I +N +
Sbjct: 22 EIISVLDYSHCSLQQVPKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDL 81
Query: 512 QTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELY-VI 336
LP + +L NLK++ S N +Q FP+ I + L +++ S N I+++P G ++L +
Sbjct: 82 SNLPTTIASLVNLKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLT 141
Query: 335 ELNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIHTVSVDGNLF 165
+L L+ + + + + +L+IL L EN L + S+ + +++ + + N F
Sbjct: 142 QLYLNDAFLEFLPANFGRLVKLRILELREN--HLKTLPKSMHKLAQLERLDLGNNEF 196
Score = 60.5 bits (140), Expect = 6e-09
Identities = 30/82 (36%), Positives = 51/82 (62%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTL 504
LR L + +N L LP ++ K++ ++L SNKL+ LPE + ++KL VLN+S+N ++ L
Sbjct: 324 LRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLEFLPEEIGQMQKLRVLNLSDNRLKNL 383
Query: 503 PVCLKNLNNLKQVYASNNKLQA 438
P L L ++ S+N+ +A
Sbjct: 384 PFSFTKLKELAALWLSDNQSKA 405
Score = 33.9 bits (74), Expect = 0.62
Identities = 21/52 (40%), Positives = 31/52 (59%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQAL 573
KL+ +P ++ + LR L+LS N+L LP +KLK L L L N+ +AL
Sbjct: 356 KLEFLPEEIGQM-QKLRVLNLSDNRLKNLPFSFTKLKELAALWLSDNQSKAL 406
>AL158840-2|CAH70975.1| 1495|Homo sapiens leucine rich repeat
containing 7 protein.
Length = 1495
Score = 89.8 bits (213), Expect = 9e-18
Identities = 61/193 (31%), Positives = 101/193 (52%), Gaps = 9/193 (4%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
+++E+P +F+ C LR L + N LS LP ++ L +LK+L++ N +Q PE++ K
Sbjct: 62 QIEELPKQLFN-CQALRKLSIPDNDLSNLPTTIASLVNLKELDISKNGVQEFPENIKCCK 120
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITE 369
L ++ S N + LP L NL Q+Y ++ L+ P L L +L+L N +
Sbjct: 121 CLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRENHLKT 180
Query: 368 IPYGMSELYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDENCL-----SLDEIKPSLLR 207
+P M +L +E L+L NE + E L Q L+ L +D N L S+ ++K +
Sbjct: 181 LPKSMHKLAQLERLDLGNNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLKMLVYL 240
Query: 206 D---SKIHTVSVD 177
D ++I TV +D
Sbjct: 241 DMSKNRIETVDMD 253
Score = 87.0 bits (206), Expect = 6e-17
Identities = 52/163 (31%), Positives = 89/163 (54%), Gaps = 1/163 (0%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKK 546
LK +P + L L LDL N+ LP+ L ++++L++L +D+N LQ LP S+ LK
Sbjct: 178 LKTLPKSMHKLAQ-LERLDLGNNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLKM 236
Query: 545 LEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEI 366
L L++S N ++T+ + + L+ + S+N LQ P I L+ L L + N++T +
Sbjct: 237 LVYLDMSKNRIETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTML 296
Query: 365 PYGMSELYVI-ELNLSQNEISLIGEDLHQAPRLKILRLDENCL 240
P + L ++ E + S NE+ + + L+ L +DEN L
Sbjct: 297 PNTIGNLSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENFL 339
Score = 87.0 bits (206), Expect = 6e-17
Identities = 50/146 (34%), Positives = 84/146 (57%), Gaps = 1/146 (0%)
Frame = -2
Query: 674 LDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTLPVC 495
LD+SKN++ + D+S + L+ L L SN LQ LP+S+ LKKL L + +N + LP
Sbjct: 240 LDMSKNRIETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNT 299
Query: 494 LKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSEL-YVIELNLSQ 318
+ NL+ L++ S N+L++ P I L SL L + N + E+P + V ++L
Sbjct: 300 IGNLSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRS 359
Query: 317 NEISLIGEDLHQAPRLKILRLDENCL 240
N++ + E++ Q +L++L L +N L
Sbjct: 360 NKLEFLPEEIGQMQKLRVLNLSDNRL 385
Score = 83.0 bits (196), Expect = 1e-15
Identities = 49/162 (30%), Positives = 87/162 (53%), Gaps = 1/162 (0%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
+++ + +D+ S C+ L +L LS N L LPD + LK L L +D N+L LP ++ NL
Sbjct: 246 RIETVDMDI-SGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIGNLS 304
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITE 369
LE + S N +++LP + L++L+ + N L P++I +++ V+ L NK+
Sbjct: 305 LLEEFDCSCNELESLPSTIGYLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLEF 364
Query: 368 IPYGMSELYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDEN 246
+P + ++ + LNLS N + + + L L L +N
Sbjct: 365 LPEEIGQMQKLRVLNLSDNRLKNLPFSFTKLKELAALWLSDN 406
Score = 81.8 bits (193), Expect = 2e-15
Identities = 53/165 (32%), Positives = 88/165 (53%), Gaps = 1/165 (0%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKK 546
+ ++P D F+ L L L+ L LP + +L L+ L L N L+ LP+S+ L +
Sbjct: 132 ISKLP-DGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRENHLKTLPKSMHKLAQ 190
Query: 545 LEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEI 366
LE L++ NN LP L + NL++++ NN LQ P I L+ L LD+S N+I +
Sbjct: 191 LERLDLGNNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIETV 250
Query: 365 PYGMSELYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDENCLSL 234
+S +E L LS N + + + + +L L++D+N L++
Sbjct: 251 DMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTM 295
Score = 81.0 bits (191), Expect = 4e-15
Identities = 49/177 (27%), Positives = 99/177 (55%), Gaps = 2/177 (1%)
Frame = -2
Query: 689 DVLRNLDLSKNKLSVLPDDLSKLKH-LKQLNLDSNKLQALPESLINLKKLEVLNISNNFV 513
+++ LD S L +P ++ + L++L LD+N+++ LP+ L N + L L+I +N +
Sbjct: 27 EIISVLDYSHCSLQQVPKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDL 86
Query: 512 QTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELY-VI 336
LP + +L NLK++ S N +Q FP+ I + L +++ S N I+++P G ++L +
Sbjct: 87 SNLPTTIASLVNLKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLT 146
Query: 335 ELNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIHTVSVDGNLF 165
+L L+ + + + + +L+IL L EN L + S+ + +++ + + N F
Sbjct: 147 QLYLNDAFLEFLPANFGRLVKLRILELREN--HLKTLPKSMHKLAQLERLDLGNNEF 201
Score = 60.5 bits (140), Expect = 6e-09
Identities = 30/82 (36%), Positives = 51/82 (62%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTL 504
LR L + +N L LP ++ K++ ++L SNKL+ LPE + ++KL VLN+S+N ++ L
Sbjct: 329 LRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLEFLPEEIGQMQKLRVLNLSDNRLKNL 388
Query: 503 PVCLKNLNNLKQVYASNNKLQA 438
P L L ++ S+N+ +A
Sbjct: 389 PFSFTKLKELAALWLSDNQSKA 410
Score = 33.9 bits (74), Expect = 0.62
Identities = 21/52 (40%), Positives = 31/52 (59%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQAL 573
KL+ +P ++ + LR L+LS N+L LP +KLK L L L N+ +AL
Sbjct: 361 KLEFLPEEIGQM-QKLRVLNLSDNRLKNLPFSFTKLKELAALWLSDNQSKAL 411
>AL158840-1|CAH70974.1| 1537|Homo sapiens leucine rich repeat
containing 7 protein.
Length = 1537
Score = 89.8 bits (213), Expect = 9e-18
Identities = 61/193 (31%), Positives = 101/193 (52%), Gaps = 9/193 (4%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
+++E+P +F+ C LR L + N LS LP ++ L +LK+L++ N +Q PE++ K
Sbjct: 57 QIEELPKQLFN-CQALRKLSIPDNDLSNLPTTIASLVNLKELDISKNGVQEFPENIKCCK 115
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITE 369
L ++ S N + LP L NL Q+Y ++ L+ P L L +L+L N +
Sbjct: 116 CLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRENHLKT 175
Query: 368 IPYGMSELYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDENCL-----SLDEIKPSLLR 207
+P M +L +E L+L NE + E L Q L+ L +D N L S+ ++K +
Sbjct: 176 LPKSMHKLAQLERLDLGNNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLKMLVYL 235
Query: 206 D---SKIHTVSVD 177
D ++I TV +D
Sbjct: 236 DMSKNRIETVDMD 248
Score = 87.0 bits (206), Expect = 6e-17
Identities = 52/163 (31%), Positives = 89/163 (54%), Gaps = 1/163 (0%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKK 546
LK +P + L L LDL N+ LP+ L ++++L++L +D+N LQ LP S+ LK
Sbjct: 173 LKTLPKSMHKLAQ-LERLDLGNNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLKM 231
Query: 545 LEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEI 366
L L++S N ++T+ + + L+ + S+N LQ P I L+ L L + N++T +
Sbjct: 232 LVYLDMSKNRIETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTML 291
Query: 365 PYGMSELYVI-ELNLSQNEISLIGEDLHQAPRLKILRLDENCL 240
P + L ++ E + S NE+ + + L+ L +DEN L
Sbjct: 292 PNTIGNLSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENFL 334
Score = 87.0 bits (206), Expect = 6e-17
Identities = 50/146 (34%), Positives = 84/146 (57%), Gaps = 1/146 (0%)
Frame = -2
Query: 674 LDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTLPVC 495
LD+SKN++ + D+S + L+ L L SN LQ LP+S+ LKKL L + +N + LP
Sbjct: 235 LDMSKNRIETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNT 294
Query: 494 LKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSEL-YVIELNLSQ 318
+ NL+ L++ S N+L++ P I L SL L + N + E+P + V ++L
Sbjct: 295 IGNLSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRS 354
Query: 317 NEISLIGEDLHQAPRLKILRLDENCL 240
N++ + E++ Q +L++L L +N L
Sbjct: 355 NKLEFLPEEIGQMQKLRVLNLSDNRL 380
Score = 83.0 bits (196), Expect = 1e-15
Identities = 49/162 (30%), Positives = 87/162 (53%), Gaps = 1/162 (0%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
+++ + +D+ S C+ L +L LS N L LPD + LK L L +D N+L LP ++ NL
Sbjct: 241 RIETVDMDI-SGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIGNLS 299
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITE 369
LE + S N +++LP + L++L+ + N L P++I +++ V+ L NK+
Sbjct: 300 LLEEFDCSCNELESLPSTIGYLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLEF 359
Query: 368 IPYGMSELYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDEN 246
+P + ++ + LNLS N + + + L L L +N
Sbjct: 360 LPEEIGQMQKLRVLNLSDNRLKNLPFSFTKLKELAALWLSDN 401
Score = 81.8 bits (193), Expect = 2e-15
Identities = 53/165 (32%), Positives = 88/165 (53%), Gaps = 1/165 (0%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKK 546
+ ++P D F+ L L L+ L LP + +L L+ L L N L+ LP+S+ L +
Sbjct: 127 ISKLP-DGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRENHLKTLPKSMHKLAQ 185
Query: 545 LEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEI 366
LE L++ NN LP L + NL++++ NN LQ P I L+ L LD+S N+I +
Sbjct: 186 LERLDLGNNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIETV 245
Query: 365 PYGMSELYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDENCLSL 234
+S +E L LS N + + + + +L L++D+N L++
Sbjct: 246 DMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTM 290
Score = 81.0 bits (191), Expect = 4e-15
Identities = 49/177 (27%), Positives = 99/177 (55%), Gaps = 2/177 (1%)
Frame = -2
Query: 689 DVLRNLDLSKNKLSVLPDDLSKLKH-LKQLNLDSNKLQALPESLINLKKLEVLNISNNFV 513
+++ LD S L +P ++ + L++L LD+N+++ LP+ L N + L L+I +N +
Sbjct: 22 EIISVLDYSHCSLQQVPKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDL 81
Query: 512 QTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELY-VI 336
LP + +L NLK++ S N +Q FP+ I + L +++ S N I+++P G ++L +
Sbjct: 82 SNLPTTIASLVNLKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLT 141
Query: 335 ELNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIHTVSVDGNLF 165
+L L+ + + + + +L+IL L EN L + S+ + +++ + + N F
Sbjct: 142 QLYLNDAFLEFLPANFGRLVKLRILELREN--HLKTLPKSMHKLAQLERLDLGNNEF 196
Score = 60.5 bits (140), Expect = 6e-09
Identities = 30/82 (36%), Positives = 51/82 (62%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTL 504
LR L + +N L LP ++ K++ ++L SNKL+ LPE + ++KL VLN+S+N ++ L
Sbjct: 324 LRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLEFLPEEIGQMQKLRVLNLSDNRLKNL 383
Query: 503 PVCLKNLNNLKQVYASNNKLQA 438
P L L ++ S+N+ +A
Sbjct: 384 PFSFTKLKELAALWLSDNQSKA 405
Score = 33.9 bits (74), Expect = 0.62
Identities = 21/52 (40%), Positives = 31/52 (59%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQAL 573
KL+ +P ++ + LR L+LS N+L LP +KLK L L L N+ +AL
Sbjct: 356 KLEFLPEEIGQM-QKLRVLNLSDNRLKNLPFSFTKLKELAALWLSDNQSKAL 406
>AL157948-2|CAI22426.1| 1495|Homo sapiens leucine rich repeat
containing 7 protein.
Length = 1495
Score = 89.8 bits (213), Expect = 9e-18
Identities = 61/193 (31%), Positives = 101/193 (52%), Gaps = 9/193 (4%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
+++E+P +F+ C LR L + N LS LP ++ L +LK+L++ N +Q PE++ K
Sbjct: 62 QIEELPKQLFN-CQALRKLSIPDNDLSNLPTTIASLVNLKELDISKNGVQEFPENIKCCK 120
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITE 369
L ++ S N + LP L NL Q+Y ++ L+ P L L +L+L N +
Sbjct: 121 CLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRENHLKT 180
Query: 368 IPYGMSELYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDENCL-----SLDEIKPSLLR 207
+P M +L +E L+L NE + E L Q L+ L +D N L S+ ++K +
Sbjct: 181 LPKSMHKLAQLERLDLGNNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLKMLVYL 240
Query: 206 D---SKIHTVSVD 177
D ++I TV +D
Sbjct: 241 DMSKNRIETVDMD 253
Score = 87.0 bits (206), Expect = 6e-17
Identities = 52/163 (31%), Positives = 89/163 (54%), Gaps = 1/163 (0%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKK 546
LK +P + L L LDL N+ LP+ L ++++L++L +D+N LQ LP S+ LK
Sbjct: 178 LKTLPKSMHKLAQ-LERLDLGNNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLKM 236
Query: 545 LEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEI 366
L L++S N ++T+ + + L+ + S+N LQ P I L+ L L + N++T +
Sbjct: 237 LVYLDMSKNRIETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTML 296
Query: 365 PYGMSELYVI-ELNLSQNEISLIGEDLHQAPRLKILRLDENCL 240
P + L ++ E + S NE+ + + L+ L +DEN L
Sbjct: 297 PNTIGNLSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENFL 339
Score = 87.0 bits (206), Expect = 6e-17
Identities = 50/146 (34%), Positives = 84/146 (57%), Gaps = 1/146 (0%)
Frame = -2
Query: 674 LDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTLPVC 495
LD+SKN++ + D+S + L+ L L SN LQ LP+S+ LKKL L + +N + LP
Sbjct: 240 LDMSKNRIETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNT 299
Query: 494 LKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSEL-YVIELNLSQ 318
+ NL+ L++ S N+L++ P I L SL L + N + E+P + V ++L
Sbjct: 300 IGNLSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRS 359
Query: 317 NEISLIGEDLHQAPRLKILRLDENCL 240
N++ + E++ Q +L++L L +N L
Sbjct: 360 NKLEFLPEEIGQMQKLRVLNLSDNRL 385
Score = 83.0 bits (196), Expect = 1e-15
Identities = 49/162 (30%), Positives = 87/162 (53%), Gaps = 1/162 (0%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
+++ + +D+ S C+ L +L LS N L LPD + LK L L +D N+L LP ++ NL
Sbjct: 246 RIETVDMDI-SGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIGNLS 304
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITE 369
LE + S N +++LP + L++L+ + N L P++I +++ V+ L NK+
Sbjct: 305 LLEEFDCSCNELESLPSTIGYLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLEF 364
Query: 368 IPYGMSELYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDEN 246
+P + ++ + LNLS N + + + L L L +N
Sbjct: 365 LPEEIGQMQKLRVLNLSDNRLKNLPFSFTKLKELAALWLSDN 406
Score = 81.8 bits (193), Expect = 2e-15
Identities = 53/165 (32%), Positives = 88/165 (53%), Gaps = 1/165 (0%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKK 546
+ ++P D F+ L L L+ L LP + +L L+ L L N L+ LP+S+ L +
Sbjct: 132 ISKLP-DGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRENHLKTLPKSMHKLAQ 190
Query: 545 LEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEI 366
LE L++ NN LP L + NL++++ NN LQ P I L+ L LD+S N+I +
Sbjct: 191 LERLDLGNNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIETV 250
Query: 365 PYGMSELYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDENCLSL 234
+S +E L LS N + + + + +L L++D+N L++
Sbjct: 251 DMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTM 295
Score = 81.0 bits (191), Expect = 4e-15
Identities = 49/177 (27%), Positives = 99/177 (55%), Gaps = 2/177 (1%)
Frame = -2
Query: 689 DVLRNLDLSKNKLSVLPDDLSKLKH-LKQLNLDSNKLQALPESLINLKKLEVLNISNNFV 513
+++ LD S L +P ++ + L++L LD+N+++ LP+ L N + L L+I +N +
Sbjct: 27 EIISVLDYSHCSLQQVPKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDL 86
Query: 512 QTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELY-VI 336
LP + +L NLK++ S N +Q FP+ I + L +++ S N I+++P G ++L +
Sbjct: 87 SNLPTTIASLVNLKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLT 146
Query: 335 ELNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIHTVSVDGNLF 165
+L L+ + + + + +L+IL L EN L + S+ + +++ + + N F
Sbjct: 147 QLYLNDAFLEFLPANFGRLVKLRILELREN--HLKTLPKSMHKLAQLERLDLGNNEF 201
Score = 60.5 bits (140), Expect = 6e-09
Identities = 30/82 (36%), Positives = 51/82 (62%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTL 504
LR L + +N L LP ++ K++ ++L SNKL+ LPE + ++KL VLN+S+N ++ L
Sbjct: 329 LRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLEFLPEEIGQMQKLRVLNLSDNRLKNL 388
Query: 503 PVCLKNLNNLKQVYASNNKLQA 438
P L L ++ S+N+ +A
Sbjct: 389 PFSFTKLKELAALWLSDNQSKA 410
Score = 33.9 bits (74), Expect = 0.62
Identities = 21/52 (40%), Positives = 31/52 (59%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQAL 573
KL+ +P ++ + LR L+LS N+L LP +KLK L L L N+ +AL
Sbjct: 361 KLEFLPEEIGQM-QKLRVLNLSDNRLKNLPFSFTKLKELAALWLSDNQSKAL 411
>AL157948-1|CAI22425.1| 1537|Homo sapiens leucine rich repeat
containing 7 protein.
Length = 1537
Score = 89.8 bits (213), Expect = 9e-18
Identities = 61/193 (31%), Positives = 101/193 (52%), Gaps = 9/193 (4%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
+++E+P +F+ C LR L + N LS LP ++ L +LK+L++ N +Q PE++ K
Sbjct: 57 QIEELPKQLFN-CQALRKLSIPDNDLSNLPTTIASLVNLKELDISKNGVQEFPENIKCCK 115
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITE 369
L ++ S N + LP L NL Q+Y ++ L+ P L L +L+L N +
Sbjct: 116 CLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRENHLKT 175
Query: 368 IPYGMSELYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDENCL-----SLDEIKPSLLR 207
+P M +L +E L+L NE + E L Q L+ L +D N L S+ ++K +
Sbjct: 176 LPKSMHKLAQLERLDLGNNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLKMLVYL 235
Query: 206 D---SKIHTVSVD 177
D ++I TV +D
Sbjct: 236 DMSKNRIETVDMD 248
Score = 87.0 bits (206), Expect = 6e-17
Identities = 52/163 (31%), Positives = 89/163 (54%), Gaps = 1/163 (0%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKK 546
LK +P + L L LDL N+ LP+ L ++++L++L +D+N LQ LP S+ LK
Sbjct: 173 LKTLPKSMHKLAQ-LERLDLGNNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLKM 231
Query: 545 LEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEI 366
L L++S N ++T+ + + L+ + S+N LQ P I L+ L L + N++T +
Sbjct: 232 LVYLDMSKNRIETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTML 291
Query: 365 PYGMSELYVI-ELNLSQNEISLIGEDLHQAPRLKILRLDENCL 240
P + L ++ E + S NE+ + + L+ L +DEN L
Sbjct: 292 PNTIGNLSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENFL 334
Score = 87.0 bits (206), Expect = 6e-17
Identities = 50/146 (34%), Positives = 84/146 (57%), Gaps = 1/146 (0%)
Frame = -2
Query: 674 LDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTLPVC 495
LD+SKN++ + D+S + L+ L L SN LQ LP+S+ LKKL L + +N + LP
Sbjct: 235 LDMSKNRIETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNT 294
Query: 494 LKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSEL-YVIELNLSQ 318
+ NL+ L++ S N+L++ P I L SL L + N + E+P + V ++L
Sbjct: 295 IGNLSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRS 354
Query: 317 NEISLIGEDLHQAPRLKILRLDENCL 240
N++ + E++ Q +L++L L +N L
Sbjct: 355 NKLEFLPEEIGQMQKLRVLNLSDNRL 380
Score = 83.0 bits (196), Expect = 1e-15
Identities = 49/162 (30%), Positives = 87/162 (53%), Gaps = 1/162 (0%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
+++ + +D+ S C+ L +L LS N L LPD + LK L L +D N+L LP ++ NL
Sbjct: 241 RIETVDMDI-SGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIGNLS 299
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITE 369
LE + S N +++LP + L++L+ + N L P++I +++ V+ L NK+
Sbjct: 300 LLEEFDCSCNELESLPSTIGYLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLEF 359
Query: 368 IPYGMSELYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDEN 246
+P + ++ + LNLS N + + + L L L +N
Sbjct: 360 LPEEIGQMQKLRVLNLSDNRLKNLPFSFTKLKELAALWLSDN 401
Score = 81.8 bits (193), Expect = 2e-15
Identities = 53/165 (32%), Positives = 88/165 (53%), Gaps = 1/165 (0%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKK 546
+ ++P D F+ L L L+ L LP + +L L+ L L N L+ LP+S+ L +
Sbjct: 127 ISKLP-DGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRENHLKTLPKSMHKLAQ 185
Query: 545 LEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEI 366
LE L++ NN LP L + NL++++ NN LQ P I L+ L LD+S N+I +
Sbjct: 186 LERLDLGNNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIETV 245
Query: 365 PYGMSELYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDENCLSL 234
+S +E L LS N + + + + +L L++D+N L++
Sbjct: 246 DMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTM 290
Score = 81.0 bits (191), Expect = 4e-15
Identities = 49/177 (27%), Positives = 99/177 (55%), Gaps = 2/177 (1%)
Frame = -2
Query: 689 DVLRNLDLSKNKLSVLPDDLSKLKH-LKQLNLDSNKLQALPESLINLKKLEVLNISNNFV 513
+++ LD S L +P ++ + L++L LD+N+++ LP+ L N + L L+I +N +
Sbjct: 22 EIISVLDYSHCSLQQVPKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDL 81
Query: 512 QTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELY-VI 336
LP + +L NLK++ S N +Q FP+ I + L +++ S N I+++P G ++L +
Sbjct: 82 SNLPTTIASLVNLKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLT 141
Query: 335 ELNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIHTVSVDGNLF 165
+L L+ + + + + +L+IL L EN L + S+ + +++ + + N F
Sbjct: 142 QLYLNDAFLEFLPANFGRLVKLRILELREN--HLKTLPKSMHKLAQLERLDLGNNEF 196
Score = 60.5 bits (140), Expect = 6e-09
Identities = 30/82 (36%), Positives = 51/82 (62%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTL 504
LR L + +N L LP ++ K++ ++L SNKL+ LPE + ++KL VLN+S+N ++ L
Sbjct: 324 LRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLEFLPEEIGQMQKLRVLNLSDNRLKNL 383
Query: 503 PVCLKNLNNLKQVYASNNKLQA 438
P L L ++ S+N+ +A
Sbjct: 384 PFSFTKLKELAALWLSDNQSKA 405
Score = 33.9 bits (74), Expect = 0.62
Identities = 21/52 (40%), Positives = 31/52 (59%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQAL 573
KL+ +P ++ + LR L+LS N+L LP +KLK L L L N+ +AL
Sbjct: 356 KLEFLPEEIGQM-QKLRVLNLSDNRLKNLPFSFTKLKELAALWLSDNQSKAL 406
>AL117353-1|CAI23423.1| 1495|Homo sapiens leucine rich repeat
containing 7 protein.
Length = 1495
Score = 89.8 bits (213), Expect = 9e-18
Identities = 61/193 (31%), Positives = 101/193 (52%), Gaps = 9/193 (4%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
+++E+P +F+ C LR L + N LS LP ++ L +LK+L++ N +Q PE++ K
Sbjct: 62 QIEELPKQLFN-CQALRKLSIPDNDLSNLPTTIASLVNLKELDISKNGVQEFPENIKCCK 120
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITE 369
L ++ S N + LP L NL Q+Y ++ L+ P L L +L+L N +
Sbjct: 121 CLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRENHLKT 180
Query: 368 IPYGMSELYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDENCL-----SLDEIKPSLLR 207
+P M +L +E L+L NE + E L Q L+ L +D N L S+ ++K +
Sbjct: 181 LPKSMHKLAQLERLDLGNNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLKMLVYL 240
Query: 206 D---SKIHTVSVD 177
D ++I TV +D
Sbjct: 241 DMSKNRIETVDMD 253
Score = 87.0 bits (206), Expect = 6e-17
Identities = 52/163 (31%), Positives = 89/163 (54%), Gaps = 1/163 (0%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKK 546
LK +P + L L LDL N+ LP+ L ++++L++L +D+N LQ LP S+ LK
Sbjct: 178 LKTLPKSMHKLAQ-LERLDLGNNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLKM 236
Query: 545 LEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEI 366
L L++S N ++T+ + + L+ + S+N LQ P I L+ L L + N++T +
Sbjct: 237 LVYLDMSKNRIETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTML 296
Query: 365 PYGMSELYVI-ELNLSQNEISLIGEDLHQAPRLKILRLDENCL 240
P + L ++ E + S NE+ + + L+ L +DEN L
Sbjct: 297 PNTIGNLSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENFL 339
Score = 87.0 bits (206), Expect = 6e-17
Identities = 50/146 (34%), Positives = 84/146 (57%), Gaps = 1/146 (0%)
Frame = -2
Query: 674 LDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTLPVC 495
LD+SKN++ + D+S + L+ L L SN LQ LP+S+ LKKL L + +N + LP
Sbjct: 240 LDMSKNRIETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNT 299
Query: 494 LKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSEL-YVIELNLSQ 318
+ NL+ L++ S N+L++ P I L SL L + N + E+P + V ++L
Sbjct: 300 IGNLSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRS 359
Query: 317 NEISLIGEDLHQAPRLKILRLDENCL 240
N++ + E++ Q +L++L L +N L
Sbjct: 360 NKLEFLPEEIGQMQKLRVLNLSDNRL 385
Score = 83.0 bits (196), Expect = 1e-15
Identities = 49/162 (30%), Positives = 87/162 (53%), Gaps = 1/162 (0%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
+++ + +D+ S C+ L +L LS N L LPD + LK L L +D N+L LP ++ NL
Sbjct: 246 RIETVDMDI-SGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIGNLS 304
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITE 369
LE + S N +++LP + L++L+ + N L P++I +++ V+ L NK+
Sbjct: 305 LLEEFDCSCNELESLPSTIGYLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLEF 364
Query: 368 IPYGMSELYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDEN 246
+P + ++ + LNLS N + + + L L L +N
Sbjct: 365 LPEEIGQMQKLRVLNLSDNRLKNLPFSFTKLKELAALWLSDN 406
Score = 81.8 bits (193), Expect = 2e-15
Identities = 53/165 (32%), Positives = 88/165 (53%), Gaps = 1/165 (0%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKK 546
+ ++P D F+ L L L+ L LP + +L L+ L L N L+ LP+S+ L +
Sbjct: 132 ISKLP-DGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRENHLKTLPKSMHKLAQ 190
Query: 545 LEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEI 366
LE L++ NN LP L + NL++++ NN LQ P I L+ L LD+S N+I +
Sbjct: 191 LERLDLGNNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIETV 250
Query: 365 PYGMSELYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDENCLSL 234
+S +E L LS N + + + + +L L++D+N L++
Sbjct: 251 DMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTM 295
Score = 81.0 bits (191), Expect = 4e-15
Identities = 49/177 (27%), Positives = 99/177 (55%), Gaps = 2/177 (1%)
Frame = -2
Query: 689 DVLRNLDLSKNKLSVLPDDLSKLKH-LKQLNLDSNKLQALPESLINLKKLEVLNISNNFV 513
+++ LD S L +P ++ + L++L LD+N+++ LP+ L N + L L+I +N +
Sbjct: 27 EIISVLDYSHCSLQQVPKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDL 86
Query: 512 QTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELY-VI 336
LP + +L NLK++ S N +Q FP+ I + L +++ S N I+++P G ++L +
Sbjct: 87 SNLPTTIASLVNLKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLT 146
Query: 335 ELNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIHTVSVDGNLF 165
+L L+ + + + + +L+IL L EN L + S+ + +++ + + N F
Sbjct: 147 QLYLNDAFLEFLPANFGRLVKLRILELREN--HLKTLPKSMHKLAQLERLDLGNNEF 201
Score = 60.5 bits (140), Expect = 6e-09
Identities = 30/82 (36%), Positives = 51/82 (62%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTL 504
LR L + +N L LP ++ K++ ++L SNKL+ LPE + ++KL VLN+S+N ++ L
Sbjct: 329 LRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLEFLPEEIGQMQKLRVLNLSDNRLKNL 388
Query: 503 PVCLKNLNNLKQVYASNNKLQA 438
P L L ++ S+N+ +A
Sbjct: 389 PFSFTKLKELAALWLSDNQSKA 410
Score = 33.9 bits (74), Expect = 0.62
Identities = 21/52 (40%), Positives = 31/52 (59%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQAL 573
KL+ +P ++ + LR L+LS N+L LP +KLK L L L N+ +AL
Sbjct: 361 KLEFLPEEIGQM-QKLRVLNLSDNRLKNLPFSFTKLKELAALWLSDNQSKAL 411
>AF434715-1|AAL28133.1| 1537|Homo sapiens densin-180 protein.
Length = 1537
Score = 89.8 bits (213), Expect = 9e-18
Identities = 61/193 (31%), Positives = 101/193 (52%), Gaps = 9/193 (4%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
+++E+P +F+ C LR L + N LS LP ++ L +LK+L++ N +Q PE++ K
Sbjct: 57 QIEELPKQLFN-CQALRKLSIPDNDLSNLPTTIASLVNLKELDISKNGVQEFPENIKCCK 115
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITE 369
L ++ S N + LP L NL Q+Y ++ L+ P L L +L+L N +
Sbjct: 116 CLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRENHLKT 175
Query: 368 IPYGMSELYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDENCL-----SLDEIKPSLLR 207
+P M +L +E L+L NE + E L Q L+ L +D N L S+ ++K +
Sbjct: 176 LPKSMHKLAQLERLDLGNNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLKMLVYL 235
Query: 206 D---SKIHTVSVD 177
D ++I TV +D
Sbjct: 236 DMSKNRIETVDMD 248
Score = 87.0 bits (206), Expect = 6e-17
Identities = 52/163 (31%), Positives = 89/163 (54%), Gaps = 1/163 (0%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKK 546
LK +P + L L LDL N+ LP+ L ++++L++L +D+N LQ LP S+ LK
Sbjct: 173 LKTLPKSMHKLAQ-LERLDLGNNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLKM 231
Query: 545 LEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEI 366
L L++S N ++T+ + + L+ + S+N LQ P I L+ L L + N++T +
Sbjct: 232 LVYLDMSKNRIETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTML 291
Query: 365 PYGMSELYVI-ELNLSQNEISLIGEDLHQAPRLKILRLDENCL 240
P + L ++ E + S NE+ + + L+ L +DEN L
Sbjct: 292 PNTIGNLSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENFL 334
Score = 87.0 bits (206), Expect = 6e-17
Identities = 50/146 (34%), Positives = 84/146 (57%), Gaps = 1/146 (0%)
Frame = -2
Query: 674 LDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTLPVC 495
LD+SKN++ + D+S + L+ L L SN LQ LP+S+ LKKL L + +N + LP
Sbjct: 235 LDMSKNRIETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNT 294
Query: 494 LKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSEL-YVIELNLSQ 318
+ NL+ L++ S N+L++ P I L SL L + N + E+P + V ++L
Sbjct: 295 IGNLSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRS 354
Query: 317 NEISLIGEDLHQAPRLKILRLDENCL 240
N++ + E++ Q +L++L L +N L
Sbjct: 355 NKLEFLPEEIGQMQKLRVLNLSDNRL 380
Score = 83.0 bits (196), Expect = 1e-15
Identities = 49/162 (30%), Positives = 87/162 (53%), Gaps = 1/162 (0%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
+++ + +D+ S C+ L +L LS N L LPD + LK L L +D N+L LP ++ NL
Sbjct: 241 RIETVDMDI-SGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIGNLS 299
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITE 369
LE + S N +++LP + L++L+ + N L P++I +++ V+ L NK+
Sbjct: 300 LLEEFDCSCNELESLPSTIGYLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLEF 359
Query: 368 IPYGMSELYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDEN 246
+P + ++ + LNLS N + + + L L L +N
Sbjct: 360 LPEEIGQMQKLRVLNLSDNRLKNLPFSFTKLKELAALWLSDN 401
Score = 81.8 bits (193), Expect = 2e-15
Identities = 53/165 (32%), Positives = 88/165 (53%), Gaps = 1/165 (0%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKK 546
+ ++P D F+ L L L+ L LP + +L L+ L L N L+ LP+S+ L +
Sbjct: 127 ISKLP-DGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRENHLKTLPKSMHKLAQ 185
Query: 545 LEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEI 366
LE L++ NN LP L + NL++++ NN LQ P I L+ L LD+S N+I +
Sbjct: 186 LERLDLGNNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIETV 245
Query: 365 PYGMSELYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDENCLSL 234
+S +E L LS N + + + + +L L++D+N L++
Sbjct: 246 DMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTM 290
Score = 81.0 bits (191), Expect = 4e-15
Identities = 49/177 (27%), Positives = 99/177 (55%), Gaps = 2/177 (1%)
Frame = -2
Query: 689 DVLRNLDLSKNKLSVLPDDLSKLKH-LKQLNLDSNKLQALPESLINLKKLEVLNISNNFV 513
+++ LD S L +P ++ + L++L LD+N+++ LP+ L N + L L+I +N +
Sbjct: 22 EIISVLDYSHCSLQQVPKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDL 81
Query: 512 QTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELY-VI 336
LP + +L NLK++ S N +Q FP+ I + L +++ S N I+++P G ++L +
Sbjct: 82 SNLPTTIASLVNLKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLT 141
Query: 335 ELNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIHTVSVDGNLF 165
+L L+ + + + + +L+IL L EN L + S+ + +++ + + N F
Sbjct: 142 QLYLNDAFLEFLPANFGRLVKLRILELREN--HLKTLPKSMHKLAQLERLDLGNNEF 196
Score = 60.5 bits (140), Expect = 6e-09
Identities = 30/82 (36%), Positives = 51/82 (62%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTL 504
LR L + +N L LP ++ K++ ++L SNKL+ LPE + ++KL VLN+S+N ++ L
Sbjct: 324 LRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLEFLPEEIGQMQKLRVLNLSDNRLKNL 383
Query: 503 PVCLKNLNNLKQVYASNNKLQA 438
P L L ++ S+N+ +A
Sbjct: 384 PFSFTKLKELAALWLSDNQSKA 405
Score = 33.9 bits (74), Expect = 0.62
Identities = 21/52 (40%), Positives = 31/52 (59%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQAL 573
KL+ +P ++ + LR L+LS N+L LP +KLK L L L N+ +AL
Sbjct: 356 KLEFLPEEIGQM-QKLRVLNLSDNRLKNLPFSFTKLKELAALWLSDNQSKAL 406
>L12535-1|AAA60292.1| 277|Homo sapiens RSU-1 protein.
Length = 277
Score = 86.6 bits (205), Expect = 8e-17
Identities = 60/187 (32%), Positives = 99/187 (52%), Gaps = 8/187 (4%)
Frame = -2
Query: 674 LDLSKNKLSVLPD--DLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTLP 501
+D+S +S + D L L H+ QL L NKL +P ++ LK LEVLN NN ++ LP
Sbjct: 20 VDMSDRGISNMLDVNGLFTLSHITQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQIEELP 79
Query: 500 VCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITE--IPYGMSELYVIE-L 330
+ +L LK + N+L P+ L +L+VLDL++N ++E +P L + L
Sbjct: 80 TQISSLQKLKHLNLGMNRLNTLPRGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRAL 139
Query: 329 NLSQNEISLIGEDLHQAPRLKILRL-DENCLSLDEIKPSLLRDSKIHTVSVDGNLFE--P 159
LS N+ ++ D+ + +L+IL L D + +SL + L + ++H + GN P
Sbjct: 140 YLSDNDFEILPPDIGKLTKLQILSLRDNDLISLPKEIGELTQLKELH---IQGNRLTVLP 196
Query: 158 KQLAXLE 138
+L L+
Sbjct: 197 PELGNLD 203
Score = 71.3 bits (167), Expect = 3e-12
Identities = 47/160 (29%), Positives = 93/160 (58%), Gaps = 3/160 (1%)
Frame = -2
Query: 704 VFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNIS 525
+F+L + + L LS NKL+++P ++++LK+L+ LN +N+++ LP + +L+KL+ LN+
Sbjct: 36 LFTLSHITQ-LVLSHNKLTMVPPNIAELKNLEVLNFFNNQIEELPTQISSLQKLKHLNLG 94
Query: 524 NNFVQTLPVCLKNLNNLKQVYASNNKL--QAFPKQILGLQSLDVLDLSHNKITEIPYGMS 351
N + TLP +L L+ + + N L + P L +L L LS N +P +
Sbjct: 95 MNRLNTLPRGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIG 154
Query: 350 ELYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDENCLSL 234
+L ++ L+L N++ + +++ + +LK L + N L++
Sbjct: 155 KLTKLQILSLRDNDLISLPKEIGELTQLKELHIQGNRLTV 194
Score = 52.4 bits (120), Expect = 2e-06
Identities = 33/86 (38%), Positives = 47/86 (54%), Gaps = 2/86 (2%)
Frame = -2
Query: 701 FSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISN 522
F LR L LS N +LP D+ KL L+ L+L N L +LP+ + L +L+ L+I
Sbjct: 130 FFYLTTLRALYLSDNDFEILPPDIGKLTKLQILSLRDNDLISLPKEIGELTQLKELHIQG 189
Query: 521 NFVQTLPVCLKNLN--NLKQVYASNN 450
N + LP L NL+ KQV+ + N
Sbjct: 190 NRLTVLPPELGNLDLTGQKQVFKAEN 215
>CR541840-1|CAG46639.1| 277|Homo sapiens RSU1 protein.
Length = 277
Score = 86.6 bits (205), Expect = 8e-17
Identities = 60/187 (32%), Positives = 99/187 (52%), Gaps = 8/187 (4%)
Frame = -2
Query: 674 LDLSKNKLSVLPD--DLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTLP 501
+D+S +S + D L L H+ QL L NKL +P ++ LK LEVLN NN ++ LP
Sbjct: 20 VDMSDRGISNMLDVNGLFTLSHITQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQIEELP 79
Query: 500 VCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITE--IPYGMSELYVIE-L 330
+ +L LK + N+L P+ L +L+VLDL++N ++E +P L + L
Sbjct: 80 TQISSLQKLKHLNLGMNRLNTLPRGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRAL 139
Query: 329 NLSQNEISLIGEDLHQAPRLKILRL-DENCLSLDEIKPSLLRDSKIHTVSVDGNLFE--P 159
LS N+ ++ D+ + +L+IL L D + +SL + L + ++H + GN P
Sbjct: 140 YLSDNDFEILPPDIGKLTKLQILSLRDNDLISLPKEIGELTQLKELH---IQGNRLTVLP 196
Query: 158 KQLAXLE 138
+L L+
Sbjct: 197 PELGNLD 203
Score = 71.3 bits (167), Expect = 3e-12
Identities = 47/160 (29%), Positives = 93/160 (58%), Gaps = 3/160 (1%)
Frame = -2
Query: 704 VFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNIS 525
+F+L + + L LS NKL+++P ++++LK+L+ LN +N+++ LP + +L+KL+ LN+
Sbjct: 36 LFTLSHITQ-LVLSHNKLTMVPPNIAELKNLEVLNFFNNQIEELPTQISSLQKLKHLNLG 94
Query: 524 NNFVQTLPVCLKNLNNLKQVYASNNKL--QAFPKQILGLQSLDVLDLSHNKITEIPYGMS 351
N + TLP +L L+ + + N L + P L +L L LS N +P +
Sbjct: 95 MNRLNTLPRGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIG 154
Query: 350 ELYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDENCLSL 234
+L ++ L+L N++ + +++ + +LK L + N L++
Sbjct: 155 KLTKLQILSLRDNDLISLPKEIGELTQLKELHIQGNRLTV 194
Score = 52.4 bits (120), Expect = 2e-06
Identities = 33/86 (38%), Positives = 47/86 (54%), Gaps = 2/86 (2%)
Frame = -2
Query: 701 FSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISN 522
F LR L LS N +LP D+ KL L+ L+L N L +LP+ + L +L+ L+I
Sbjct: 130 FFYLTTLRALYLSDNDFEILPPDIGKLTKLQILSLRDNDLISLPKEIGELTQLKELHIQG 189
Query: 521 NFVQTLPVCLKNLN--NLKQVYASNN 450
N + LP L NL+ KQV+ + N
Sbjct: 190 NRLTVLPPELGNLDLTGQKQVFKAEN 215
>CR536521-1|CAG38758.1| 277|Homo sapiens RSU1 protein.
Length = 277
Score = 86.6 bits (205), Expect = 8e-17
Identities = 60/187 (32%), Positives = 99/187 (52%), Gaps = 8/187 (4%)
Frame = -2
Query: 674 LDLSKNKLSVLPD--DLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTLP 501
+D+S +S + D L L H+ QL L NKL +P ++ LK LEVLN NN ++ LP
Sbjct: 20 VDMSDRGISNMLDVNGLFTLSHITQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQIEELP 79
Query: 500 VCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITE--IPYGMSELYVIE-L 330
+ +L LK + N+L P+ L +L+VLDL++N ++E +P L + L
Sbjct: 80 TQISSLQKLKHLNLGMNRLNTLPRGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRAL 139
Query: 329 NLSQNEISLIGEDLHQAPRLKILRL-DENCLSLDEIKPSLLRDSKIHTVSVDGNLFE--P 159
LS N+ ++ D+ + +L+IL L D + +SL + L + ++H + GN P
Sbjct: 140 YLSDNDFEILPPDIGKLTKLQILSLRDNDLISLPKEIGELTQLKELH---IQGNRLTVLP 196
Query: 158 KQLAXLE 138
+L L+
Sbjct: 197 PELGNLD 203
Score = 71.3 bits (167), Expect = 3e-12
Identities = 47/160 (29%), Positives = 93/160 (58%), Gaps = 3/160 (1%)
Frame = -2
Query: 704 VFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNIS 525
+F+L + + L LS NKL+++P ++++LK+L+ LN +N+++ LP + +L+KL+ LN+
Sbjct: 36 LFTLSHITQ-LVLSHNKLTMVPPNIAELKNLEVLNFFNNQIEELPTQISSLQKLKHLNLG 94
Query: 524 NNFVQTLPVCLKNLNNLKQVYASNNKL--QAFPKQILGLQSLDVLDLSHNKITEIPYGMS 351
N + TLP +L L+ + + N L + P L +L L LS N +P +
Sbjct: 95 MNRLNTLPRGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIG 154
Query: 350 ELYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDENCLSL 234
+L ++ L+L N++ + +++ + +LK L + N L++
Sbjct: 155 KLTKLQILSLRDNDLISLPKEIGELTQLKELHIQGNRLTV 194
Score = 52.4 bits (120), Expect = 2e-06
Identities = 33/86 (38%), Positives = 47/86 (54%), Gaps = 2/86 (2%)
Frame = -2
Query: 701 FSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISN 522
F LR L LS N +LP D+ KL L+ L+L N L +LP+ + L +L+ L+I
Sbjct: 130 FFYLTTLRALYLSDNDFEILPPDIGKLTKLQILSLRDNDLISLPKEIGELTQLKELHIQG 189
Query: 521 NFVQTLPVCLKNLN--NLKQVYASNN 450
N + LP L NL+ KQV+ + N
Sbjct: 190 NRLTVLPPELGNLDLTGQKQVFKAEN 215
>BC015644-1|AAH15644.1| 277|Homo sapiens Ras suppressor protein 1
protein.
Length = 277
Score = 86.6 bits (205), Expect = 8e-17
Identities = 60/187 (32%), Positives = 99/187 (52%), Gaps = 8/187 (4%)
Frame = -2
Query: 674 LDLSKNKLSVLPD--DLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTLP 501
+D+S +S + D L L H+ QL L NKL +P ++ LK LEVLN NN ++ LP
Sbjct: 20 VDMSDRGISNMLDVNGLFTLSHITQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQIEELP 79
Query: 500 VCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITE--IPYGMSELYVIE-L 330
+ +L LK + N+L P+ L +L+VLDL++N ++E +P L + L
Sbjct: 80 TQISSLQKLKHLNLGMNRLNTLPRGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRAL 139
Query: 329 NLSQNEISLIGEDLHQAPRLKILRL-DENCLSLDEIKPSLLRDSKIHTVSVDGNLFE--P 159
LS N+ ++ D+ + +L+IL L D + +SL + L + ++H + GN P
Sbjct: 140 YLSDNDFEILPPDIGKLTKLQILSLRDNDLISLPKEIGELTQLKELH---IQGNRLTVLP 196
Query: 158 KQLAXLE 138
+L L+
Sbjct: 197 PELGNLD 203
Score = 71.3 bits (167), Expect = 3e-12
Identities = 47/160 (29%), Positives = 93/160 (58%), Gaps = 3/160 (1%)
Frame = -2
Query: 704 VFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNIS 525
+F+L + + L LS NKL+++P ++++LK+L+ LN +N+++ LP + +L+KL+ LN+
Sbjct: 36 LFTLSHITQ-LVLSHNKLTMVPPNIAELKNLEVLNFFNNQIEELPTQISSLQKLKHLNLG 94
Query: 524 NNFVQTLPVCLKNLNNLKQVYASNNKL--QAFPKQILGLQSLDVLDLSHNKITEIPYGMS 351
N + TLP +L L+ + + N L + P L +L L LS N +P +
Sbjct: 95 MNRLNTLPRGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIG 154
Query: 350 ELYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDENCLSL 234
+L ++ L+L N++ + +++ + +LK L + N L++
Sbjct: 155 KLTKLQILSLRDNDLISLPKEIGELTQLKELHIQGNRLTV 194
Score = 52.4 bits (120), Expect = 2e-06
Identities = 33/86 (38%), Positives = 47/86 (54%), Gaps = 2/86 (2%)
Frame = -2
Query: 701 FSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISN 522
F LR L LS N +LP D+ KL L+ L+L N L +LP+ + L +L+ L+I
Sbjct: 130 FFYLTTLRALYLSDNDFEILPPDIGKLTKLQILSLRDNDLISLPKEIGELTQLKELHIQG 189
Query: 521 NFVQTLPVCLKNLN--NLKQVYASNN 450
N + LP L NL+ KQV+ + N
Sbjct: 190 NRLTVLPPELGNLDLTGQKQVFKAEN 215
>BC008691-1|AAH08691.1| 277|Homo sapiens RSU1 protein protein.
Length = 277
Score = 86.6 bits (205), Expect = 8e-17
Identities = 60/187 (32%), Positives = 99/187 (52%), Gaps = 8/187 (4%)
Frame = -2
Query: 674 LDLSKNKLSVLPD--DLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTLP 501
+D+S +S + D L L H+ QL L NKL +P ++ LK LEVLN NN ++ LP
Sbjct: 20 VDMSDRGISNMLDVNGLFTLSHITQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQIEELP 79
Query: 500 VCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITE--IPYGMSELYVIE-L 330
+ +L LK + N+L P+ L +L+VLDL++N ++E +P L + L
Sbjct: 80 TQISSLQKLKHLNLGMNRLNTLPRGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRAL 139
Query: 329 NLSQNEISLIGEDLHQAPRLKILRL-DENCLSLDEIKPSLLRDSKIHTVSVDGNLFE--P 159
LS N+ ++ D+ + +L+IL L D + +SL + L + ++H + GN P
Sbjct: 140 YLSDNDFEILPPDIGKLTKLQILSLRDNDLISLPKEIGELTQLKELH---IQGNRLTVLP 196
Query: 158 KQLAXLE 138
+L L+
Sbjct: 197 PELGNLD 203
Score = 71.3 bits (167), Expect = 3e-12
Identities = 47/160 (29%), Positives = 93/160 (58%), Gaps = 3/160 (1%)
Frame = -2
Query: 704 VFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNIS 525
+F+L + + L LS NKL+++P ++++LK+L+ LN +N+++ LP + +L+KL+ LN+
Sbjct: 36 LFTLSHITQ-LVLSHNKLTMVPPNIAELKNLEVLNFFNNQIEELPTQISSLQKLKHLNLG 94
Query: 524 NNFVQTLPVCLKNLNNLKQVYASNNKL--QAFPKQILGLQSLDVLDLSHNKITEIPYGMS 351
N + TLP +L L+ + + N L + P L +L L LS N +P +
Sbjct: 95 MNRLNTLPRGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIG 154
Query: 350 ELYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDENCLSL 234
+L ++ L+L N++ + +++ + +LK L + N L++
Sbjct: 155 KLTKLQILSLRDNDLISLPKEIGELTQLKELHIQGNRLTV 194
Score = 52.4 bits (120), Expect = 2e-06
Identities = 33/86 (38%), Positives = 47/86 (54%), Gaps = 2/86 (2%)
Frame = -2
Query: 701 FSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISN 522
F LR L LS N +LP D+ KL L+ L+L N L +LP+ + L +L+ L+I
Sbjct: 130 FFYLTTLRALYLSDNDFEILPPDIGKLTKLQILSLRDNDLISLPKEIGELTQLKELHIQG 189
Query: 521 NFVQTLPVCLKNLN--NLKQVYASNN 450
N + LP L NL+ KQV+ + N
Sbjct: 190 NRLTVLPPELGNLDLTGQKQVFKAEN 215
>BC005993-1|AAH05993.1| 277|Homo sapiens Ras suppressor protein 1
protein.
Length = 277
Score = 86.6 bits (205), Expect = 8e-17
Identities = 60/187 (32%), Positives = 99/187 (52%), Gaps = 8/187 (4%)
Frame = -2
Query: 674 LDLSKNKLSVLPD--DLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTLP 501
+D+S +S + D L L H+ QL L NKL +P ++ LK LEVLN NN ++ LP
Sbjct: 20 VDMSDRGISNMLDVNGLFTLSHITQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQIEELP 79
Query: 500 VCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITE--IPYGMSELYVIE-L 330
+ +L LK + N+L P+ L +L+VLDL++N ++E +P L + L
Sbjct: 80 TQISSLQKLKHLNLGMNRLNTLPRGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRAL 139
Query: 329 NLSQNEISLIGEDLHQAPRLKILRL-DENCLSLDEIKPSLLRDSKIHTVSVDGNLFE--P 159
LS N+ ++ D+ + +L+IL L D + +SL + L + ++H + GN P
Sbjct: 140 YLSDNDFEILPPDIGKLTKLQILSLRDNDLISLPKEIGELTQLKELH---IQGNRLTVLP 196
Query: 158 KQLAXLE 138
+L L+
Sbjct: 197 PELGNLD 203
Score = 71.3 bits (167), Expect = 3e-12
Identities = 47/160 (29%), Positives = 93/160 (58%), Gaps = 3/160 (1%)
Frame = -2
Query: 704 VFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNIS 525
+F+L + + L LS NKL+++P ++++LK+L+ LN +N+++ LP + +L+KL+ LN+
Sbjct: 36 LFTLSHITQ-LVLSHNKLTMVPPNIAELKNLEVLNFFNNQIEELPTQISSLQKLKHLNLG 94
Query: 524 NNFVQTLPVCLKNLNNLKQVYASNNKL--QAFPKQILGLQSLDVLDLSHNKITEIPYGMS 351
N + TLP +L L+ + + N L + P L +L L LS N +P +
Sbjct: 95 MNRLNTLPRGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIG 154
Query: 350 ELYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDENCLSL 234
+L ++ L+L N++ + +++ + +LK L + N L++
Sbjct: 155 KLTKLQILSLRDNDLISLPKEIGELTQLKELHIQGNRLTV 194
Score = 52.4 bits (120), Expect = 2e-06
Identities = 33/86 (38%), Positives = 47/86 (54%), Gaps = 2/86 (2%)
Frame = -2
Query: 701 FSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISN 522
F LR L LS N +LP D+ KL L+ L+L N L +LP+ + L +L+ L+I
Sbjct: 130 FFYLTTLRALYLSDNDFEILPPDIGKLTKLQILSLRDNDLISLPKEIGELTQLKELHIQG 189
Query: 521 NFVQTLPVCLKNLN--NLKQVYASNN 450
N + LP L NL+ KQV+ + N
Sbjct: 190 NRLTVLPPELGNLDLTGQKQVFKAEN 215
>AL365215-3|CAH73633.1| 277|Homo sapiens Ras suppressor protein 1
protein.
Length = 277
Score = 86.6 bits (205), Expect = 8e-17
Identities = 60/187 (32%), Positives = 99/187 (52%), Gaps = 8/187 (4%)
Frame = -2
Query: 674 LDLSKNKLSVLPD--DLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTLP 501
+D+S +S + D L L H+ QL L NKL +P ++ LK LEVLN NN ++ LP
Sbjct: 20 VDMSDRGISNMLDVNGLFTLSHITQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQIEELP 79
Query: 500 VCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITE--IPYGMSELYVIE-L 330
+ +L LK + N+L P+ L +L+VLDL++N ++E +P L + L
Sbjct: 80 TQISSLQKLKHLNLGMNRLNTLPRGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRAL 139
Query: 329 NLSQNEISLIGEDLHQAPRLKILRL-DENCLSLDEIKPSLLRDSKIHTVSVDGNLFE--P 159
LS N+ ++ D+ + +L+IL L D + +SL + L + ++H + GN P
Sbjct: 140 YLSDNDFEILPPDIGKLTKLQILSLRDNDLISLPKEIGELTQLKELH---IQGNRLTVLP 196
Query: 158 KQLAXLE 138
+L L+
Sbjct: 197 PELGNLD 203
Score = 71.3 bits (167), Expect = 3e-12
Identities = 47/160 (29%), Positives = 93/160 (58%), Gaps = 3/160 (1%)
Frame = -2
Query: 704 VFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNIS 525
+F+L + + L LS NKL+++P ++++LK+L+ LN +N+++ LP + +L+KL+ LN+
Sbjct: 36 LFTLSHITQ-LVLSHNKLTMVPPNIAELKNLEVLNFFNNQIEELPTQISSLQKLKHLNLG 94
Query: 524 NNFVQTLPVCLKNLNNLKQVYASNNKL--QAFPKQILGLQSLDVLDLSHNKITEIPYGMS 351
N + TLP +L L+ + + N L + P L +L L LS N +P +
Sbjct: 95 MNRLNTLPRGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIG 154
Query: 350 ELYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDENCLSL 234
+L ++ L+L N++ + +++ + +LK L + N L++
Sbjct: 155 KLTKLQILSLRDNDLISLPKEIGELTQLKELHIQGNRLTV 194
Score = 52.4 bits (120), Expect = 2e-06
Identities = 33/86 (38%), Positives = 47/86 (54%), Gaps = 2/86 (2%)
Frame = -2
Query: 701 FSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISN 522
F LR L LS N +LP D+ KL L+ L+L N L +LP+ + L +L+ L+I
Sbjct: 130 FFYLTTLRALYLSDNDFEILPPDIGKLTKLQILSLRDNDLISLPKEIGELTQLKELHIQG 189
Query: 521 NFVQTLPVCLKNLN--NLKQVYASNN 450
N + LP L NL+ KQV+ + N
Sbjct: 190 NRLTVLPPELGNLDLTGQKQVFKAEN 215
>U80184-1|AAC02796.1| 1269|Homo sapiens FLII protein.
Length = 1269
Score = 86.2 bits (204), Expect = 1e-16
Identities = 66/187 (35%), Positives = 96/187 (51%), Gaps = 6/187 (3%)
Frame = -2
Query: 683 LRNLDLSKN--KLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQ 510
+R +DLS N K P+++ + L+ L L+ L LPE L L+KLE L++S+N +
Sbjct: 10 VRGVDLSGNDFKGGYFPENVKAMTSLRWLKLNRTGLCYLPEELAALQKLEHLSVSHNNLT 69
Query: 509 TLPVCLKNLNNLKQVYASNNKLQ--AFPKQILGLQSLDVLDLSHNKITEIPYGMSEL-YV 339
TL L +L +L+ + A N L+ P I L L VLDLSHN++TE P + +
Sbjct: 70 TLHGELSSLPSLRAIVARANSLKNSGVPDDIFKLDDLSVLDLSHNQLTECPRELENAKNM 129
Query: 338 IELNLSQNEISLIGEDLH-QAPRLKILRLDENCLSLDEIKPSLLRDSKIHTVSVDGNLFE 162
+ LNLS N I I L L L L EN L+ + P + R + T+ ++GN
Sbjct: 130 LVLNLSHNSIDTIPNQLFINLTDLLYLDLSEN--RLESLPPQMRRLVHLQTLVLNGNPLL 187
Query: 161 PKQLAXL 141
QL L
Sbjct: 188 HAQLRQL 194
Score = 76.2 bits (179), Expect = 1e-13
Identities = 57/185 (30%), Positives = 101/185 (54%), Gaps = 5/185 (2%)
Frame = -2
Query: 716 IPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESL-INLKKLE 540
+P D+F L D L LDLS N+L+ P +L K++ LNL N + +P L INL L
Sbjct: 96 VPDDIFKLDD-LSVLDLSHNQLTECPRELENAKNMLVLNLSHNSIDTIPNQLFINLTDLL 154
Query: 539 VLNISNNFVQTLPVCLKNLNNLKQVYASNNK-LQAFPKQILGLQSLDVLDLSHNKITE-- 369
L++S N +++LP ++ L +L+ + + N L A +Q+ + +L L L + T+
Sbjct: 155 YLDLSENRLESLPPQMRRLVHLQTLVLNGNPLLHAQLRQLPAMTALQTLHLRSTQRTQSN 214
Query: 368 IPYGMSEL-YVIELNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIH 192
+P + L + +++LS N+++ + E L+ P L+ L L N + E+ SL D +H
Sbjct: 215 LPTSLEGLSNLADVDLSCNDLTRVPECLYTLPSLRRLNLSSN--QITEL--SLCIDQWVH 270
Query: 191 TVSVD 177
+++
Sbjct: 271 VETLN 275
Score = 72.1 bits (169), Expect = 2e-12
Identities = 54/179 (30%), Positives = 88/179 (49%), Gaps = 5/179 (2%)
Frame = -2
Query: 650 SVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTLPVCLKNLNNLK 471
S LP L L +L ++L N L +PE L L L LN+S+N + L +C+ +++
Sbjct: 213 SNLPTSLEGLSNLADVDLSCNDLTRVPECLYTLPSLRRLNLSSNQITELSLCIDQWVHVE 272
Query: 470 QVYASNNKLQAFPKQILGLQSLDVLDLSHNKI--TEIPYGMSELYVI-ELNLSQNEISLI 300
+ S N+L + P I L L L L+ NK+ +P G+ +L + E + N + L+
Sbjct: 273 TLNLSRNQLTSLPSAICKLSKLKKLYLNSNKLDFDGLPSGIGKLTNLEEFMAANNNLELV 332
Query: 299 GEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIHTVSVDGNLFEPKQLA--XLEGYN 129
E L + P+L+ L L++N L L + ++ V + NL P + A E YN
Sbjct: 333 PESLCRCPKLRKLVLNKNHLVTLPEAIHFLTEIEVLDVRENPNLVMPPKPADRAAEWYN 391
Score = 70.1 bits (164), Expect = 8e-12
Identities = 44/149 (29%), Positives = 82/149 (55%), Gaps = 3/149 (2%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTL 504
L ++DLS N L+ +P+ L L L++LNL SN++ L + +E LN+S N + +L
Sbjct: 225 LADVDLSCNDLTRVPECLYTLPSLRRLNLSSNQITELSLCIDQWVHVETLNLSRNQLTSL 284
Query: 503 PVCLKNLNNLKQVYASNNKL--QAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVI-E 333
P + L+ LK++Y ++NKL P I L +L+ ++N + +P + + +
Sbjct: 285 PSAICKLSKLKKLYLNSNKLDFDGLPSGIGKLTNLEEFMAANNNLELVPESLCRCPKLRK 344
Query: 332 LNLSQNEISLIGEDLHQAPRLKILRLDEN 246
L L++N + + E +H +++L + EN
Sbjct: 345 LVLNKNHLVTLPEAIHFLTEIEVLDVREN 373
Score = 64.5 bits (150), Expect = 4e-10
Identities = 50/168 (29%), Positives = 81/168 (48%), Gaps = 6/168 (3%)
Frame = -2
Query: 656 KLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTLPVCL-KNLN 480
K S +PDD+ KL L L+L N+L P L N K + VLN+S+N + T+P L NL
Sbjct: 92 KNSGVPDDIFKLDDLSVLDLSHNQLTECPRELENAKNMLVLNLSHNSIDTIPNQLFINLT 151
Query: 479 NLKQVYASNNKLQAFPKQILGLQSLDVLDLS-----HNKITEIPYGMSELYVIELNLSQN 315
+L + S N+L++ P Q+ L L L L+ H ++ ++P M+ L + L +Q
Sbjct: 152 DLLYLDLSENRLESLPPQMRRLVHLQTLVLNGNPLLHAQLRQLP-AMTALQTLHLRSTQR 210
Query: 314 EISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIHTVSVDGN 171
S + L L +D +C L + L + +++ N
Sbjct: 211 TQSNLPTSLEGLSNL--ADVDLSCNDLTRVPECLYTLPSLRRLNLSSN 256
Score = 45.6 bits (103), Expect = 2e-04
Identities = 30/101 (29%), Positives = 49/101 (48%), Gaps = 2/101 (1%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSV--LPDDLSKLKHLKQLNLDSNKLQALPESLIN 555
+L +P + L L+ L L+ NKL LP + KL +L++ +N L+ +PESL
Sbjct: 280 QLTSLPSAICKLSK-LKKLYLNSNKLDFDGLPSGIGKLTNLEEFMAANNNLELVPESLCR 338
Query: 554 LKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFP 432
KL L ++ N + TLP + L ++ + N P
Sbjct: 339 CPKLRKLVLNKNHLVTLPEAIHFLTEIEVLDVRENPNLVMP 379
>U01184-1|AAC03568.1| 1268|Homo sapiens flightless-I homolog
protein.
Length = 1268
Score = 86.2 bits (204), Expect = 1e-16
Identities = 66/187 (35%), Positives = 96/187 (51%), Gaps = 6/187 (3%)
Frame = -2
Query: 683 LRNLDLSKN--KLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQ 510
+R +DLS N K P+++ + L+ L L+ L LPE L L+KLE L++S+N +
Sbjct: 9 VRGVDLSGNDFKGGYFPENVKAMTSLRWLKLNRTGLCYLPEELAALQKLEHLSVSHNNLT 68
Query: 509 TLPVCLKNLNNLKQVYASNNKLQ--AFPKQILGLQSLDVLDLSHNKITEIPYGMSEL-YV 339
TL L +L +L+ + A N L+ P I L L VLDLSHN++TE P + +
Sbjct: 69 TLHGELSSLPSLRAIVARANSLKNSGVPDDIFKLDDLSVLDLSHNQLTECPRELENAKNM 128
Query: 338 IELNLSQNEISLIGEDLH-QAPRLKILRLDENCLSLDEIKPSLLRDSKIHTVSVDGNLFE 162
+ LNLS N I I L L L L EN L+ + P + R + T+ ++GN
Sbjct: 129 LVLNLSHNSIDTIPNQLFINLTDLLYLDLSEN--RLESLPPQMRRLVHLQTLVLNGNPLL 186
Query: 161 PKQLAXL 141
QL L
Sbjct: 187 HAQLRQL 193
Score = 76.2 bits (179), Expect = 1e-13
Identities = 57/185 (30%), Positives = 101/185 (54%), Gaps = 5/185 (2%)
Frame = -2
Query: 716 IPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESL-INLKKLE 540
+P D+F L D L LDLS N+L+ P +L K++ LNL N + +P L INL L
Sbjct: 95 VPDDIFKLDD-LSVLDLSHNQLTECPRELENAKNMLVLNLSHNSIDTIPNQLFINLTDLL 153
Query: 539 VLNISNNFVQTLPVCLKNLNNLKQVYASNNK-LQAFPKQILGLQSLDVLDLSHNKITE-- 369
L++S N +++LP ++ L +L+ + + N L A +Q+ + +L L L + T+
Sbjct: 154 YLDLSENRLESLPPQMRRLVHLQTLVLNGNPLLHAQLRQLPAMTALQTLHLRSTQRTQSN 213
Query: 368 IPYGMSEL-YVIELNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIH 192
+P + L + +++LS N+++ + E L+ P L+ L L N + E+ SL D +H
Sbjct: 214 LPTSLEGLSNLADVDLSCNDLTRVPECLYTLPSLRRLNLSSN--QITEL--SLCIDQWVH 269
Query: 191 TVSVD 177
+++
Sbjct: 270 VETLN 274
Score = 72.1 bits (169), Expect = 2e-12
Identities = 54/179 (30%), Positives = 88/179 (49%), Gaps = 5/179 (2%)
Frame = -2
Query: 650 SVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTLPVCLKNLNNLK 471
S LP L L +L ++L N L +PE L L L LN+S+N + L +C+ +++
Sbjct: 212 SNLPTSLEGLSNLADVDLSCNDLTRVPECLYTLPSLRRLNLSSNQITELSLCIDQWVHVE 271
Query: 470 QVYASNNKLQAFPKQILGLQSLDVLDLSHNKI--TEIPYGMSELYVI-ELNLSQNEISLI 300
+ S N+L + P I L L L L+ NK+ +P G+ +L + E + N + L+
Sbjct: 272 TLNLSRNQLTSLPSAICKLSKLKKLYLNSNKLDFDGLPSGIGKLTNLEEFMAANNNLELV 331
Query: 299 GEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIHTVSVDGNLFEPKQLA--XLEGYN 129
E L + P+L+ L L++N L L + ++ V + NL P + A E YN
Sbjct: 332 PESLCRCPKLRKLVLNKNHLVTLPEAIHFLTEIEVLDVRENPNLVMPPKPADRAAEWYN 390
Score = 70.1 bits (164), Expect = 8e-12
Identities = 44/149 (29%), Positives = 82/149 (55%), Gaps = 3/149 (2%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTL 504
L ++DLS N L+ +P+ L L L++LNL SN++ L + +E LN+S N + +L
Sbjct: 224 LADVDLSCNDLTRVPECLYTLPSLRRLNLSSNQITELSLCIDQWVHVETLNLSRNQLTSL 283
Query: 503 PVCLKNLNNLKQVYASNNKL--QAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVI-E 333
P + L+ LK++Y ++NKL P I L +L+ ++N + +P + + +
Sbjct: 284 PSAICKLSKLKKLYLNSNKLDFDGLPSGIGKLTNLEEFMAANNNLELVPESLCRCPKLRK 343
Query: 332 LNLSQNEISLIGEDLHQAPRLKILRLDEN 246
L L++N + + E +H +++L + EN
Sbjct: 344 LVLNKNHLVTLPEAIHFLTEIEVLDVREN 372
Score = 64.5 bits (150), Expect = 4e-10
Identities = 50/168 (29%), Positives = 81/168 (48%), Gaps = 6/168 (3%)
Frame = -2
Query: 656 KLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTLPVCL-KNLN 480
K S +PDD+ KL L L+L N+L P L N K + VLN+S+N + T+P L NL
Sbjct: 91 KNSGVPDDIFKLDDLSVLDLSHNQLTECPRELENAKNMLVLNLSHNSIDTIPNQLFINLT 150
Query: 479 NLKQVYASNNKLQAFPKQILGLQSLDVLDLS-----HNKITEIPYGMSELYVIELNLSQN 315
+L + S N+L++ P Q+ L L L L+ H ++ ++P M+ L + L +Q
Sbjct: 151 DLLYLDLSENRLESLPPQMRRLVHLQTLVLNGNPLLHAQLRQLP-AMTALQTLHLRSTQR 209
Query: 314 EISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIHTVSVDGN 171
S + L L +D +C L + L + +++ N
Sbjct: 210 TQSNLPTSLEGLSNL--ADVDLSCNDLTRVPECLYTLPSLRRLNLSSN 255
Score = 45.6 bits (103), Expect = 2e-04
Identities = 30/101 (29%), Positives = 49/101 (48%), Gaps = 2/101 (1%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSV--LPDDLSKLKHLKQLNLDSNKLQALPESLIN 555
+L +P + L L+ L L+ NKL LP + KL +L++ +N L+ +PESL
Sbjct: 279 QLTSLPSAICKLSK-LKKLYLNSNKLDFDGLPSGIGKLTNLEEFMAANNNLELVPESLCR 337
Query: 554 LKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFP 432
KL L ++ N + TLP + L ++ + N P
Sbjct: 338 CPKLRKLVLNKNHLVTLPEAIHFLTEIEVLDVRENPNLVMP 378
>BC025300-1|AAH25300.1| 1269|Homo sapiens flightless I homolog
(Drosophila) protein.
Length = 1269
Score = 86.2 bits (204), Expect = 1e-16
Identities = 66/187 (35%), Positives = 96/187 (51%), Gaps = 6/187 (3%)
Frame = -2
Query: 683 LRNLDLSKN--KLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQ 510
+R +DLS N K P+++ + L+ L L+ L LPE L L+KLE L++S+N +
Sbjct: 10 VRGVDLSGNDFKGGYFPENVKAMTSLRWLKLNRTGLCYLPEELAALQKLEHLSVSHNNLT 69
Query: 509 TLPVCLKNLNNLKQVYASNNKLQ--AFPKQILGLQSLDVLDLSHNKITEIPYGMSEL-YV 339
TL L +L +L+ + A N L+ P I L L VLDLSHN++TE P + +
Sbjct: 70 TLHGELSSLPSLRAIVARANSLKNSGVPDDIFKLDDLSVLDLSHNQLTECPRELENAKNM 129
Query: 338 IELNLSQNEISLIGEDLH-QAPRLKILRLDENCLSLDEIKPSLLRDSKIHTVSVDGNLFE 162
+ LNLS N I I L L L L EN L+ + P + R + T+ ++GN
Sbjct: 130 LVLNLSHNSIDTIPNQLFINLTDLLYLDLSEN--RLESLPPQMRRLVHLQTLVLNGNPLL 187
Query: 161 PKQLAXL 141
QL L
Sbjct: 188 HAQLRQL 194
Score = 76.2 bits (179), Expect = 1e-13
Identities = 57/185 (30%), Positives = 101/185 (54%), Gaps = 5/185 (2%)
Frame = -2
Query: 716 IPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESL-INLKKLE 540
+P D+F L D L LDLS N+L+ P +L K++ LNL N + +P L INL L
Sbjct: 96 VPDDIFKLDD-LSVLDLSHNQLTECPRELENAKNMLVLNLSHNSIDTIPNQLFINLTDLL 154
Query: 539 VLNISNNFVQTLPVCLKNLNNLKQVYASNNK-LQAFPKQILGLQSLDVLDLSHNKITE-- 369
L++S N +++LP ++ L +L+ + + N L A +Q+ + +L L L + T+
Sbjct: 155 YLDLSENRLESLPPQMRRLVHLQTLVLNGNPLLHAQLRQLPAMTALQTLHLRSTQRTQSN 214
Query: 368 IPYGMSEL-YVIELNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIH 192
+P + L + +++LS N+++ + E L+ P L+ L L N + E+ SL D +H
Sbjct: 215 LPTSLEGLSNLADVDLSCNDLTRVPECLYTLPSLRRLNLSSN--QITEL--SLCIDQWVH 270
Query: 191 TVSVD 177
+++
Sbjct: 271 VETLN 275
Score = 72.1 bits (169), Expect = 2e-12
Identities = 54/179 (30%), Positives = 88/179 (49%), Gaps = 5/179 (2%)
Frame = -2
Query: 650 SVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTLPVCLKNLNNLK 471
S LP L L +L ++L N L +PE L L L LN+S+N + L +C+ +++
Sbjct: 213 SNLPTSLEGLSNLADVDLSCNDLTRVPECLYTLPSLRRLNLSSNQITELSLCIDQWVHVE 272
Query: 470 QVYASNNKLQAFPKQILGLQSLDVLDLSHNKI--TEIPYGMSELYVI-ELNLSQNEISLI 300
+ S N+L + P I L L L L+ NK+ +P G+ +L + E + N + L+
Sbjct: 273 TLNLSRNQLTSLPSAICKLSKLKKLYLNSNKLDFDGLPSGIGKLTNLEEFMAANNNLELV 332
Query: 299 GEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIHTVSVDGNLFEPKQLA--XLEGYN 129
E L + P+L+ L L++N L L + ++ V + NL P + A E YN
Sbjct: 333 PESLCRCPKLRKLVLNKNHLVTLPEAIHFLTEIEVLDVRENPNLVMPPKPADRAAEWYN 391
Score = 70.1 bits (164), Expect = 8e-12
Identities = 44/149 (29%), Positives = 82/149 (55%), Gaps = 3/149 (2%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTL 504
L ++DLS N L+ +P+ L L L++LNL SN++ L + +E LN+S N + +L
Sbjct: 225 LADVDLSCNDLTRVPECLYTLPSLRRLNLSSNQITELSLCIDQWVHVETLNLSRNQLTSL 284
Query: 503 PVCLKNLNNLKQVYASNNKL--QAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVI-E 333
P + L+ LK++Y ++NKL P I L +L+ ++N + +P + + +
Sbjct: 285 PSAICKLSKLKKLYLNSNKLDFDGLPSGIGKLTNLEEFMAANNNLELVPESLCRCPKLRK 344
Query: 332 LNLSQNEISLIGEDLHQAPRLKILRLDEN 246
L L++N + + E +H +++L + EN
Sbjct: 345 LVLNKNHLVTLPEAIHFLTEIEVLDVREN 373
Score = 64.5 bits (150), Expect = 4e-10
Identities = 50/168 (29%), Positives = 81/168 (48%), Gaps = 6/168 (3%)
Frame = -2
Query: 656 KLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTLPVCL-KNLN 480
K S +PDD+ KL L L+L N+L P L N K + VLN+S+N + T+P L NL
Sbjct: 92 KNSGVPDDIFKLDDLSVLDLSHNQLTECPRELENAKNMLVLNLSHNSIDTIPNQLFINLT 151
Query: 479 NLKQVYASNNKLQAFPKQILGLQSLDVLDLS-----HNKITEIPYGMSELYVIELNLSQN 315
+L + S N+L++ P Q+ L L L L+ H ++ ++P M+ L + L +Q
Sbjct: 152 DLLYLDLSENRLESLPPQMRRLVHLQTLVLNGNPLLHAQLRQLP-AMTALQTLHLRSTQR 210
Query: 314 EISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIHTVSVDGN 171
S + L L +D +C L + L + +++ N
Sbjct: 211 TQSNLPTSLEGLSNL--ADVDLSCNDLTRVPECLYTLPSLRRLNLSSN 256
Score = 45.6 bits (103), Expect = 2e-04
Identities = 30/101 (29%), Positives = 49/101 (48%), Gaps = 2/101 (1%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSV--LPDDLSKLKHLKQLNLDSNKLQALPESLIN 555
+L +P + L L+ L L+ NKL LP + KL +L++ +N L+ +PESL
Sbjct: 280 QLTSLPSAICKLSK-LKKLYLNSNKLDFDGLPSGIGKLTNLEEFMAANNNLELVPESLCR 338
Query: 554 LKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFP 432
KL L ++ N + TLP + L ++ + N P
Sbjct: 339 CPKLRKLVLNKNHLVTLPEAIHFLTEIEVLDVRENPNLVMP 379
>BC018529-1|AAH18529.3| 683|Homo sapiens leucine-rich repeats and
calponin homology (CH) domain containing 4 protein.
Length = 683
Score = 85.8 bits (203), Expect = 1e-16
Identities = 63/191 (32%), Positives = 101/191 (52%), Gaps = 2/191 (1%)
Frame = -2
Query: 701 FSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISN 522
+ L D+ + DLS+N+ +P+ +L L+ L+L N L+ L +L NL L LN+S
Sbjct: 65 YDLSDITQ-ADLSRNRFPEVPEAACQLVSLEGLSLYHNCLRCLNPALGNLTALTYLNLSR 123
Query: 521 NFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELY 342
N + LP + L L+ + SNNKL A P I L SL LD+S N++ +P + L
Sbjct: 124 NQLSLLPPYICQLP-LRVLIVSNNKLGALPPDIGTLGSLRQLDVSSNELQSLPSELCGLS 182
Query: 341 VI-ELNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIHTVSVDGN-L 168
+ +LN+ +N++S + E+L P ++RLD +C + I S R + + +D N L
Sbjct: 183 SLRDLNVRRNQLSTLPEELGDLP---LVRLDFSCNRVSRIPVSFCRLRHLQVILLDSNPL 239
Query: 167 FEPKQLAXLEG 135
P L+G
Sbjct: 240 QSPPAQVCLKG 250
Score = 37.1 bits (82), Expect = 0.066
Identities = 19/49 (38%), Positives = 29/49 (59%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEV 537
L LD S N++S +P +L+HL+ + LDSN LQ+ P + KL +
Sbjct: 206 LVRLDFSCNRVSRIPVSFCRLRHLQVILLDSNPLQSPPAQVCLKGKLHI 254
Score = 35.1 bits (77), Expect = 0.27
Identities = 25/79 (31%), Positives = 37/79 (46%), Gaps = 4/79 (5%)
Frame = -2
Query: 458 SNNKLQAFPK---QILGLQSLDVLDLSHNKITEIPYGMSELYVIE-LNLSQNEISLIGED 291
SN +L+ FP+ + L + DLS N+ E+P +L +E L+L N + +
Sbjct: 50 SNRRLKHFPRGAARSYDLSDITQADLSRNRFPEVPEAACQLVSLEGLSLYHNCLRCLNPA 109
Query: 290 LHQAPRLKILRLDENCLSL 234
L L L L N LSL
Sbjct: 110 LGNLTALTYLNLSRNQLSL 128
>AF053356-12|AAC78793.1| 832|Homo sapiens leucin rich neuronal
protein protein.
Length = 832
Score = 85.8 bits (203), Expect = 1e-16
Identities = 63/191 (32%), Positives = 101/191 (52%), Gaps = 2/191 (1%)
Frame = -2
Query: 701 FSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISN 522
+ L D+ + DLS+N+ +P+ +L L+ L+L N L+ L +L NL L LN+S
Sbjct: 65 YDLSDITQ-ADLSRNRFPEVPEAACQLVSLEGLSLYHNCLRCLNPALGNLTALTYLNLSR 123
Query: 521 NFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELY 342
N + LP + L L+ + SNNKL A P I L SL LD+S N++ +P + L
Sbjct: 124 NQLSLLPPYICQLP-LRVLIVSNNKLGALPPDIGTLGSLRQLDVSSNELQSLPSELCGLS 182
Query: 341 VI-ELNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIHTVSVDGN-L 168
+ +LN+ +N++S + E+L P ++RLD +C + I S R + + +D N L
Sbjct: 183 SLRDLNVRRNQLSTLPEELGDLP---LVRLDFSCNRVSRIPVSFCRLRHLQVILLDSNPL 239
Query: 167 FEPKQLAXLEG 135
P L+G
Sbjct: 240 QSPPAQVCLKG 250
Score = 37.1 bits (82), Expect = 0.066
Identities = 19/49 (38%), Positives = 29/49 (59%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEV 537
L LD S N++S +P +L+HL+ + LDSN LQ+ P + KL +
Sbjct: 206 LVRLDFSCNRVSRIPVSFCRLRHLQVILLDSNPLQSPPAQVCLKGKLHI 254
Score = 35.1 bits (77), Expect = 0.27
Identities = 25/79 (31%), Positives = 37/79 (46%), Gaps = 4/79 (5%)
Frame = -2
Query: 458 SNNKLQAFPK---QILGLQSLDVLDLSHNKITEIPYGMSELYVIE-LNLSQNEISLIGED 291
SN +L+ FP+ + L + DLS N+ E+P +L +E L+L N + +
Sbjct: 50 SNRRLKHFPRGAARSYDLSDITQADLSRNRFPEVPEAACQLVSLEGLSLYHNCLRCLNPA 109
Query: 290 LHQAPRLKILRLDENCLSL 234
L L L L N LSL
Sbjct: 110 LGNLTALTYLNLSRNQLSL 128
>BC107898-1|AAI07899.1| 280|Homo sapiens RSU1 protein protein.
Length = 280
Score = 84.6 bits (200), Expect = 3e-16
Identities = 55/168 (32%), Positives = 90/168 (53%), Gaps = 6/168 (3%)
Frame = -2
Query: 623 LKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKL 444
L H+ QL L NKL +P ++ LK LEVLN NN ++ LP + +L LK + N+L
Sbjct: 42 LSHITQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQIEELPTQISSLQKLKHLNLGMNRL 101
Query: 443 QAFPKQILGLQSLDVLDLSHNKITE--IPYGMSELYVIE-LNLSQNEISLIGEDLHQAPR 273
P+ L +L+VLDL++N ++E +P L + L LS N+ ++ D+ + +
Sbjct: 102 NTLPRGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGKLTK 161
Query: 272 LKILRL-DENCLSLDEIKPSLLRDSKIHTVSVDGNLFE--PKQLAXLE 138
L+IL L D + +SL + L + ++H + GN P +L L+
Sbjct: 162 LQILSLRDNDLISLPKEIGELTQLKELH---IQGNRLTVLPPELGNLD 206
Score = 70.9 bits (166), Expect = 4e-12
Identities = 45/153 (29%), Positives = 88/153 (57%), Gaps = 3/153 (1%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTL 504
+ L LS NKL+++P ++++LK+L+ LN +N+++ LP + +L+KL+ LN+ N + TL
Sbjct: 45 ITQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQIEELPTQISSLQKLKHLNLGMNRLNTL 104
Query: 503 PVCLKNLNNLKQVYASNNKL--QAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVIE- 333
P +L L+ + + N L + P L +L L LS N +P + +L ++
Sbjct: 105 PRGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGKLTKLQI 164
Query: 332 LNLSQNEISLIGEDLHQAPRLKILRLDENCLSL 234
L+L N++ + +++ + +LK L + N L++
Sbjct: 165 LSLRDNDLISLPKEIGELTQLKELHIQGNRLTV 197
Score = 52.4 bits (120), Expect = 2e-06
Identities = 33/86 (38%), Positives = 47/86 (54%), Gaps = 2/86 (2%)
Frame = -2
Query: 701 FSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISN 522
F LR L LS N +LP D+ KL L+ L+L N L +LP+ + L +L+ L+I
Sbjct: 133 FFYLTTLRALYLSDNDFEILPPDIGKLTKLQILSLRDNDLISLPKEIGELTQLKELHIQG 192
Query: 521 NFVQTLPVCLKNLN--NLKQVYASNN 450
N + LP L NL+ KQV+ + N
Sbjct: 193 NRLTVLPPELGNLDLTGQKQVFKAEN 218
Score = 51.2 bits (117), Expect = 4e-06
Identities = 30/95 (31%), Positives = 49/95 (51%), Gaps = 2/95 (2%)
Frame = -2
Query: 701 FSLCDVLRNLDLSKNKLSV--LPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNI 528
F L LDL+ N LS LP + L L+ L L N + LP + L KL++L++
Sbjct: 108 FGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGKLTKLQILSL 167
Query: 527 SNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQI 423
+N + +LP + L LK+++ N+L P ++
Sbjct: 168 RDNDLISLPKEIGELTQLKELHIQGNRLTVLPPEL 202
>BC009239-1|AAH09239.1| 723|Homo sapiens leucine rich repeat and
sterile alpha motif containing 1 protein.
Length = 723
Score = 84.2 bits (199), Expect = 4e-16
Identities = 51/142 (35%), Positives = 80/142 (56%), Gaps = 5/142 (3%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRN--LDLSKNKL-SVLPDDLS--KLKHLKQLNLDSNKLQA 576
I+ C+L EIP F+ C VL+ L + N L S+LP S L +K L+L N+L A
Sbjct: 36 ISKCELSEIPFGAFATCKVLQKKVLIVHTNHLTSLLPKSCSLLSLATIKVLDLHDNQLTA 95
Query: 575 LPESLINLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVL 396
LP+ L L L+VLN+ N + LP + NL L+ + +NKL+ P + L+SL L
Sbjct: 96 LPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKLKELPDTVGELRSLRTL 155
Query: 395 DLSHNKITEIPYGMSELYVIEL 330
++S N+I +P ++ + +E+
Sbjct: 156 NISGNEIQRLPQMLAHVRTLEM 177
Score = 77.8 bits (183), Expect = 4e-14
Identities = 37/107 (34%), Positives = 68/107 (63%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTL 504
++ LDL N+L+ LPDDL +L L+ LN++ N+L LP S+ NL +L+ LN+ +N ++ L
Sbjct: 83 IKVLDLHDNQLTALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKLKEL 142
Query: 503 PVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIP 363
P + L +L+ + S N++Q P+ + +++L++L L + + P
Sbjct: 143 PDTVGELRSLRTLNISGNEIQRLPQMLAHVRTLEMLSLDASAMVYPP 189
Score = 65.7 bits (153), Expect = 2e-10
Identities = 49/152 (32%), Positives = 82/152 (53%), Gaps = 7/152 (4%)
Frame = -2
Query: 674 LDLSKNKLSVLPDDL---SKLKHLKQLNLDSNKLQAL-PES--LINLKKLEVLNISNNFV 513
LD+SK +LS +P K+ K L + +N L +L P+S L++L ++VL++ +N +
Sbjct: 34 LDISKCELSEIPFGAFATCKVLQKKVLIVHTNHLTSLLPKSCSLLSLATIKVLDLHDNQL 93
Query: 512 QTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVIE 333
LP L L L+ + N+L P+ I L L L++ NK+ E+P + EL +
Sbjct: 94 TALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKLKELPDTVGELRSLR 153
Query: 332 -LNLSQNEISLIGEDLHQAPRLKILRLDENCL 240
LN+S NEI + + L L++L LD + +
Sbjct: 154 TLNISGNEIQRLPQMLAHVRTLEMLSLDASAM 185
Score = 63.3 bits (147), Expect = 9e-10
Identities = 35/113 (30%), Positives = 63/113 (55%)
Frame = -2
Query: 734 DCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLIN 555
D +L +P D+ L L+ L++ +N+L LP + L L+ LN+ NKL+ LP+++
Sbjct: 90 DNQLTALPDDLGQLT-ALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKLKELPDTVGE 148
Query: 554 LKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVL 396
L+ L LNIS N +Q LP L ++ L+ + + + P+++ G + +L
Sbjct: 149 LRSLRTLNISGNEIQRLPQMLAHVRTLEMLSLDASAMVYPPREVCGAGTAAIL 201
>AY358830-1|AAQ89189.1| 723|Homo sapiens leucine-rich protein
protein.
Length = 723
Score = 84.2 bits (199), Expect = 4e-16
Identities = 51/142 (35%), Positives = 80/142 (56%), Gaps = 5/142 (3%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRN--LDLSKNKL-SVLPDDLS--KLKHLKQLNLDSNKLQA 576
I+ C+L EIP F+ C VL+ L + N L S+LP S L +K L+L N+L A
Sbjct: 36 ISKCELSEIPFGAFATCKVLQKKVLIVHTNHLTSLLPKSCSLLSLATIKVLDLHDNQLTA 95
Query: 575 LPESLINLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVL 396
LP+ L L L+VLN+ N + LP + NL L+ + +NKL+ P + L+SL L
Sbjct: 96 LPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKLKELPDTVGELRSLRTL 155
Query: 395 DLSHNKITEIPYGMSELYVIEL 330
++S N+I +P ++ + +E+
Sbjct: 156 NISGNEIQRLPQMLAHVRTLEM 177
Score = 77.8 bits (183), Expect = 4e-14
Identities = 37/107 (34%), Positives = 68/107 (63%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTL 504
++ LDL N+L+ LPDDL +L L+ LN++ N+L LP S+ NL +L+ LN+ +N ++ L
Sbjct: 83 IKVLDLHDNQLTALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKLKEL 142
Query: 503 PVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIP 363
P + L +L+ + S N++Q P+ + +++L++L L + + P
Sbjct: 143 PDTVGELRSLRTLNISGNEIQRLPQMLAHVRTLEMLSLDASAMVYPP 189
Score = 65.7 bits (153), Expect = 2e-10
Identities = 49/152 (32%), Positives = 82/152 (53%), Gaps = 7/152 (4%)
Frame = -2
Query: 674 LDLSKNKLSVLPDDL---SKLKHLKQLNLDSNKLQAL-PES--LINLKKLEVLNISNNFV 513
LD+SK +LS +P K+ K L + +N L +L P+S L++L ++VL++ +N +
Sbjct: 34 LDISKCELSEIPFGAFATCKVLQKKVLIVHTNHLTSLLPKSCSLLSLATIKVLDLHDNQL 93
Query: 512 QTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVIE 333
LP L L L+ + N+L P+ I L L L++ NK+ E+P + EL +
Sbjct: 94 TALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKLKELPDTVGELRSLR 153
Query: 332 -LNLSQNEISLIGEDLHQAPRLKILRLDENCL 240
LN+S NEI + + L L++L LD + +
Sbjct: 154 TLNISGNEIQRLPQMLAHVRTLEMLSLDASAM 185
Score = 63.3 bits (147), Expect = 9e-10
Identities = 35/113 (30%), Positives = 63/113 (55%)
Frame = -2
Query: 734 DCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLIN 555
D +L +P D+ L L+ L++ +N+L LP + L L+ LN+ NKL+ LP+++
Sbjct: 90 DNQLTALPDDLGQLT-ALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKLKELPDTVGE 148
Query: 554 LKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVL 396
L+ L LNIS N +Q LP L ++ L+ + + + P+++ G + +L
Sbjct: 149 LRSLRTLNISGNEIQRLPQMLAHVRTLEMLSLDASAMVYPPREVCGAGTAAIL 201
>AL445222-17|CAH72931.1| 696|Homo sapiens leucine rich repeat and
sterile alpha motif containing 1 protein.
Length = 696
Score = 84.2 bits (199), Expect = 4e-16
Identities = 51/142 (35%), Positives = 80/142 (56%), Gaps = 5/142 (3%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRN--LDLSKNKL-SVLPDDLS--KLKHLKQLNLDSNKLQA 576
I+ C+L EIP F+ C VL+ L + N L S+LP S L +K L+L N+L A
Sbjct: 36 ISKCELSEIPFGAFATCKVLQKKVLIVHTNHLTSLLPKSCSLLSLATIKVLDLHDNQLTA 95
Query: 575 LPESLINLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVL 396
LP+ L L L+VLN+ N + LP + NL L+ + +NKL+ P + L+SL L
Sbjct: 96 LPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKLKELPDTVGELRSLRTL 155
Query: 395 DLSHNKITEIPYGMSELYVIEL 330
++S N+I +P ++ + +E+
Sbjct: 156 NISGNEIQRLPQMLAHVRTLEM 177
Score = 77.8 bits (183), Expect = 4e-14
Identities = 37/107 (34%), Positives = 68/107 (63%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTL 504
++ LDL N+L+ LPDDL +L L+ LN++ N+L LP S+ NL +L+ LN+ +N ++ L
Sbjct: 83 IKVLDLHDNQLTALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKLKEL 142
Query: 503 PVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIP 363
P + L +L+ + S N++Q P+ + +++L++L L + + P
Sbjct: 143 PDTVGELRSLRTLNISGNEIQRLPQMLAHVRTLEMLSLDASAMVYPP 189
Score = 65.7 bits (153), Expect = 2e-10
Identities = 49/152 (32%), Positives = 82/152 (53%), Gaps = 7/152 (4%)
Frame = -2
Query: 674 LDLSKNKLSVLPDDL---SKLKHLKQLNLDSNKLQAL-PES--LINLKKLEVLNISNNFV 513
LD+SK +LS +P K+ K L + +N L +L P+S L++L ++VL++ +N +
Sbjct: 34 LDISKCELSEIPFGAFATCKVLQKKVLIVHTNHLTSLLPKSCSLLSLATIKVLDLHDNQL 93
Query: 512 QTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVIE 333
LP L L L+ + N+L P+ I L L L++ NK+ E+P + EL +
Sbjct: 94 TALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKLKELPDTVGELRSLR 153
Query: 332 -LNLSQNEISLIGEDLHQAPRLKILRLDENCL 240
LN+S NEI + + L L++L LD + +
Sbjct: 154 TLNISGNEIQRLPQMLAHVRTLEMLSLDASAM 185
Score = 63.3 bits (147), Expect = 9e-10
Identities = 35/113 (30%), Positives = 63/113 (55%)
Frame = -2
Query: 734 DCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLIN 555
D +L +P D+ L L+ L++ +N+L LP + L L+ LN+ NKL+ LP+++
Sbjct: 90 DNQLTALPDDLGQLT-ALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKLKELPDTVGE 148
Query: 554 LKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVL 396
L+ L LNIS N +Q LP L ++ L+ + + + P+++ G + +L
Sbjct: 149 LRSLRTLNISGNEIQRLPQMLAHVRTLEMLSLDASAMVYPPREVCGAGTAAIL 201
>AL445222-16|CAH72930.1| 723|Homo sapiens leucine rich repeat and
sterile alpha motif containing 1 protein.
Length = 723
Score = 84.2 bits (199), Expect = 4e-16
Identities = 51/142 (35%), Positives = 80/142 (56%), Gaps = 5/142 (3%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRN--LDLSKNKL-SVLPDDLS--KLKHLKQLNLDSNKLQA 576
I+ C+L EIP F+ C VL+ L + N L S+LP S L +K L+L N+L A
Sbjct: 36 ISKCELSEIPFGAFATCKVLQKKVLIVHTNHLTSLLPKSCSLLSLATIKVLDLHDNQLTA 95
Query: 575 LPESLINLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVL 396
LP+ L L L+VLN+ N + LP + NL L+ + +NKL+ P + L+SL L
Sbjct: 96 LPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKLKELPDTVGELRSLRTL 155
Query: 395 DLSHNKITEIPYGMSELYVIEL 330
++S N+I +P ++ + +E+
Sbjct: 156 NISGNEIQRLPQMLAHVRTLEM 177
Score = 77.8 bits (183), Expect = 4e-14
Identities = 37/107 (34%), Positives = 68/107 (63%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTL 504
++ LDL N+L+ LPDDL +L L+ LN++ N+L LP S+ NL +L+ LN+ +N ++ L
Sbjct: 83 IKVLDLHDNQLTALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKLKEL 142
Query: 503 PVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIP 363
P + L +L+ + S N++Q P+ + +++L++L L + + P
Sbjct: 143 PDTVGELRSLRTLNISGNEIQRLPQMLAHVRTLEMLSLDASAMVYPP 189
Score = 65.7 bits (153), Expect = 2e-10
Identities = 49/152 (32%), Positives = 82/152 (53%), Gaps = 7/152 (4%)
Frame = -2
Query: 674 LDLSKNKLSVLPDDL---SKLKHLKQLNLDSNKLQAL-PES--LINLKKLEVLNISNNFV 513
LD+SK +LS +P K+ K L + +N L +L P+S L++L ++VL++ +N +
Sbjct: 34 LDISKCELSEIPFGAFATCKVLQKKVLIVHTNHLTSLLPKSCSLLSLATIKVLDLHDNQL 93
Query: 512 QTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVIE 333
LP L L L+ + N+L P+ I L L L++ NK+ E+P + EL +
Sbjct: 94 TALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKLKELPDTVGELRSLR 153
Query: 332 -LNLSQNEISLIGEDLHQAPRLKILRLDENCL 240
LN+S NEI + + L L++L LD + +
Sbjct: 154 TLNISGNEIQRLPQMLAHVRTLEMLSLDASAM 185
Score = 63.3 bits (147), Expect = 9e-10
Identities = 35/113 (30%), Positives = 63/113 (55%)
Frame = -2
Query: 734 DCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLIN 555
D +L +P D+ L L+ L++ +N+L LP + L L+ LN+ NKL+ LP+++
Sbjct: 90 DNQLTALPDDLGQLT-ALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKLKELPDTVGE 148
Query: 554 LKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVL 396
L+ L LNIS N +Q LP L ++ L+ + + + P+++ G + +L
Sbjct: 149 LRSLRTLNISGNEIQRLPQMLAHVRTLEMLSLDASAMVYPPREVCGAGTAAIL 201
>AK091589-1|BAC03703.1| 723|Homo sapiens protein ( Homo sapiens
cDNA FLJ34270 fis, clone FEBRA2003100. ).
Length = 723
Score = 84.2 bits (199), Expect = 4e-16
Identities = 51/142 (35%), Positives = 80/142 (56%), Gaps = 5/142 (3%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRN--LDLSKNKL-SVLPDDLS--KLKHLKQLNLDSNKLQA 576
I+ C+L EIP F+ C VL+ L + N L S+LP S L +K L+L N+L A
Sbjct: 36 ISKCELSEIPFGAFATCKVLQKKVLIVHTNHLTSLLPKSCSLLSLATIKVLDLHDNQLTA 95
Query: 575 LPESLINLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVL 396
LP+ L L L+VLN+ N + LP + NL L+ + +NKL+ P + L+SL L
Sbjct: 96 LPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKLKELPDTVGELRSLRTL 155
Query: 395 DLSHNKITEIPYGMSELYVIEL 330
++S N+I +P ++ + +E+
Sbjct: 156 NISGNEIQRLPQMLAHVRTLEM 177
Score = 77.8 bits (183), Expect = 4e-14
Identities = 37/107 (34%), Positives = 68/107 (63%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTL 504
++ LDL N+L+ LPDDL +L L+ LN++ N+L LP S+ NL +L+ LN+ +N ++ L
Sbjct: 83 IKVLDLHDNQLTALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKLKEL 142
Query: 503 PVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIP 363
P + L +L+ + S N++Q P+ + +++L++L L + + P
Sbjct: 143 PDTVGELRSLRTLNISGNEIQRLPQMLAHVRTLEMLSLDASAMVYPP 189
Score = 65.7 bits (153), Expect = 2e-10
Identities = 49/152 (32%), Positives = 82/152 (53%), Gaps = 7/152 (4%)
Frame = -2
Query: 674 LDLSKNKLSVLPDDL---SKLKHLKQLNLDSNKLQAL-PES--LINLKKLEVLNISNNFV 513
LD+SK +LS +P K+ K L + +N L +L P+S L++L ++VL++ +N +
Sbjct: 34 LDISKCELSEIPFGAFATCKVLQKKVLIVHTNHLTSLLPKSCSLLSLATIKVLDLHDNQL 93
Query: 512 QTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVIE 333
LP L L L+ + N+L P+ I L L L++ NK+ E+P + EL +
Sbjct: 94 TALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKLKELPDTVGELRSLR 153
Query: 332 -LNLSQNEISLIGEDLHQAPRLKILRLDENCL 240
LN+S NEI + + L L++L LD + +
Sbjct: 154 TLNISGNEIQRLPQMLAHVRTLEMLSLDASAM 185
Score = 63.3 bits (147), Expect = 9e-10
Identities = 35/113 (30%), Positives = 63/113 (55%)
Frame = -2
Query: 734 DCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLIN 555
D +L +P D+ L L+ L++ +N+L LP + L L+ LN+ NKL+ LP+++
Sbjct: 90 DNQLTALPDDLGQLT-ALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKLKELPDTVGE 148
Query: 554 LKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVL 396
L+ L LNIS N +Q LP L ++ L+ + + + P+++ G + +L
Sbjct: 149 LRSLRTLNISGNEIQRLPQMLAHVRTLEMLSLDASAMVYPPREVCGAGTAAIL 201
>AK056203-1|BAB71119.1| 696|Homo sapiens protein ( Homo sapiens
cDNA FLJ31641 fis, clone NT2RI2003695, weakly similar to
TRICHOHYALIN. ).
Length = 696
Score = 84.2 bits (199), Expect = 4e-16
Identities = 51/142 (35%), Positives = 80/142 (56%), Gaps = 5/142 (3%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRN--LDLSKNKL-SVLPDDLS--KLKHLKQLNLDSNKLQA 576
I+ C+L EIP F+ C VL+ L + N L S+LP S L +K L+L N+L A
Sbjct: 36 ISKCELSEIPFGAFATCKVLQKKVLIVHTNHLTSLLPKSCSLLSLATIKVLDLHDNQLTA 95
Query: 575 LPESLINLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVL 396
LP+ L L L+VLN+ N + LP + NL L+ + +NKL+ P + L+SL L
Sbjct: 96 LPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKLKELPDTVGELRSLRTL 155
Query: 395 DLSHNKITEIPYGMSELYVIEL 330
++S N+I +P ++ + +E+
Sbjct: 156 NISGNEIQRLPQMLAHVRTLEM 177
Score = 77.8 bits (183), Expect = 4e-14
Identities = 37/107 (34%), Positives = 68/107 (63%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTL 504
++ LDL N+L+ LPDDL +L L+ LN++ N+L LP S+ NL +L+ LN+ +N ++ L
Sbjct: 83 IKVLDLHDNQLTALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKLKEL 142
Query: 503 PVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIP 363
P + L +L+ + S N++Q P+ + +++L++L L + + P
Sbjct: 143 PDTVGELRSLRTLNISGNEIQRLPQMLAHVRTLEMLSLDASAMVYPP 189
Score = 65.7 bits (153), Expect = 2e-10
Identities = 49/152 (32%), Positives = 82/152 (53%), Gaps = 7/152 (4%)
Frame = -2
Query: 674 LDLSKNKLSVLPDDL---SKLKHLKQLNLDSNKLQAL-PES--LINLKKLEVLNISNNFV 513
LD+SK +LS +P K+ K L + +N L +L P+S L++L ++VL++ +N +
Sbjct: 34 LDISKCELSEIPFGAFATCKVLQKKVLIVHTNHLTSLLPKSCSLLSLATIKVLDLHDNQL 93
Query: 512 QTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVIE 333
LP L L L+ + N+L P+ I L L L++ NK+ E+P + EL +
Sbjct: 94 TALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKLKELPDTVGELRSLR 153
Query: 332 -LNLSQNEISLIGEDLHQAPRLKILRLDENCL 240
LN+S NEI + + L L++L LD + +
Sbjct: 154 TLNISGNEIQRLPQMLAHVRTLEMLSLDASAM 185
Score = 63.3 bits (147), Expect = 9e-10
Identities = 35/113 (30%), Positives = 63/113 (55%)
Frame = -2
Query: 734 DCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLIN 555
D +L +P D+ L L+ L++ +N+L LP + L L+ LN+ NKL+ LP+++
Sbjct: 90 DNQLTALPDDLGQLT-ALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKLKELPDTVGE 148
Query: 554 LKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVL 396
L+ L LNIS N +Q LP L ++ L+ + + + P+++ G + +L
Sbjct: 149 LRSLRTLNISGNEIQRLPQMLAHVRTLEMLSLDASAMVYPPREVCGAGTAAIL 201
>AB208864-1|BAD92101.1| 1101|Homo sapiens flightless I homolog
variant protein.
Length = 1101
Score = 83.4 bits (197), Expect = 8e-16
Identities = 65/183 (35%), Positives = 93/183 (50%), Gaps = 6/183 (3%)
Frame = -2
Query: 671 DLSKN--KLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTLPV 498
DLS N K P+++ + L+ L L+ L LPE L L+KLE L++S+N + TL
Sbjct: 1 DLSGNDFKGGYFPENVKAMTSLRWLKLNRTGLCYLPEELAALQKLEHLSVSHNNLTTLHG 60
Query: 497 CLKNLNNLKQVYASNNKLQ--AFPKQILGLQSLDVLDLSHNKITEIPYGMSEL-YVIELN 327
L +L +L+ + A N L+ P I L L VLDLSHN++TE P + ++ LN
Sbjct: 61 ELSSLPSLRAIVARANSLKNSGVPDDIFKLDDLSVLDLSHNQLTECPRELENAKNMLVLN 120
Query: 326 LSQNEISLIGEDLH-QAPRLKILRLDENCLSLDEIKPSLLRDSKIHTVSVDGNLFEPKQL 150
LS N I I L L L L EN L+ + P + R + T+ ++GN QL
Sbjct: 121 LSHNSIDTIPNQLFINLTDLLYLDLSEN--RLESLPPQMRRLVHLQTLVLNGNPLLHAQL 178
Query: 149 AXL 141
L
Sbjct: 179 RQL 181
Score = 76.2 bits (179), Expect = 1e-13
Identities = 57/185 (30%), Positives = 101/185 (54%), Gaps = 5/185 (2%)
Frame = -2
Query: 716 IPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESL-INLKKLE 540
+P D+F L D L LDLS N+L+ P +L K++ LNL N + +P L INL L
Sbjct: 83 VPDDIFKLDD-LSVLDLSHNQLTECPRELENAKNMLVLNLSHNSIDTIPNQLFINLTDLL 141
Query: 539 VLNISNNFVQTLPVCLKNLNNLKQVYASNNK-LQAFPKQILGLQSLDVLDLSHNKITE-- 369
L++S N +++LP ++ L +L+ + + N L A +Q+ + +L L L + T+
Sbjct: 142 YLDLSENRLESLPPQMRRLVHLQTLVLNGNPLLHAQLRQLPAMTALQTLHLRSTQRTQSN 201
Query: 368 IPYGMSEL-YVIELNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIH 192
+P + L + +++LS N+++ + E L+ P L+ L L N + E+ SL D +H
Sbjct: 202 LPTSLEGLSNLADVDLSCNDLTRVPECLYTLPSLRRLNLSSN--QITEL--SLCIDQWVH 257
Query: 191 TVSVD 177
+++
Sbjct: 258 VETLN 262
Score = 72.1 bits (169), Expect = 2e-12
Identities = 54/179 (30%), Positives = 88/179 (49%), Gaps = 5/179 (2%)
Frame = -2
Query: 650 SVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTLPVCLKNLNNLK 471
S LP L L +L ++L N L +PE L L L LN+S+N + L +C+ +++
Sbjct: 200 SNLPTSLEGLSNLADVDLSCNDLTRVPECLYTLPSLRRLNLSSNQITELSLCIDQWVHVE 259
Query: 470 QVYASNNKLQAFPKQILGLQSLDVLDLSHNKI--TEIPYGMSELYVI-ELNLSQNEISLI 300
+ S N+L + P I L L L L+ NK+ +P G+ +L + E + N + L+
Sbjct: 260 TLNLSRNQLTSLPSAICKLSKLKKLYLNSNKLDFDGLPSGIGKLTNLEEFMAANNNLELV 319
Query: 299 GEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIHTVSVDGNLFEPKQLA--XLEGYN 129
E L + P+L+ L L++N L L + ++ V + NL P + A E YN
Sbjct: 320 PESLCRCPKLRKLVLNKNHLVTLPEAIHFLTEIEVLDVRENPNLVMPPKPADRAAEWYN 378
Score = 70.1 bits (164), Expect = 8e-12
Identities = 44/149 (29%), Positives = 82/149 (55%), Gaps = 3/149 (2%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTL 504
L ++DLS N L+ +P+ L L L++LNL SN++ L + +E LN+S N + +L
Sbjct: 212 LADVDLSCNDLTRVPECLYTLPSLRRLNLSSNQITELSLCIDQWVHVETLNLSRNQLTSL 271
Query: 503 PVCLKNLNNLKQVYASNNKL--QAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVI-E 333
P + L+ LK++Y ++NKL P I L +L+ ++N + +P + + +
Sbjct: 272 PSAICKLSKLKKLYLNSNKLDFDGLPSGIGKLTNLEEFMAANNNLELVPESLCRCPKLRK 331
Query: 332 LNLSQNEISLIGEDLHQAPRLKILRLDEN 246
L L++N + + E +H +++L + EN
Sbjct: 332 LVLNKNHLVTLPEAIHFLTEIEVLDVREN 360
Score = 64.5 bits (150), Expect = 4e-10
Identities = 50/168 (29%), Positives = 81/168 (48%), Gaps = 6/168 (3%)
Frame = -2
Query: 656 KLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTLPVCL-KNLN 480
K S +PDD+ KL L L+L N+L P L N K + VLN+S+N + T+P L NL
Sbjct: 79 KNSGVPDDIFKLDDLSVLDLSHNQLTECPRELENAKNMLVLNLSHNSIDTIPNQLFINLT 138
Query: 479 NLKQVYASNNKLQAFPKQILGLQSLDVLDLS-----HNKITEIPYGMSELYVIELNLSQN 315
+L + S N+L++ P Q+ L L L L+ H ++ ++P M+ L + L +Q
Sbjct: 139 DLLYLDLSENRLESLPPQMRRLVHLQTLVLNGNPLLHAQLRQLP-AMTALQTLHLRSTQR 197
Query: 314 EISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIHTVSVDGN 171
S + L L +D +C L + L + +++ N
Sbjct: 198 TQSNLPTSLEGLSNL--ADVDLSCNDLTRVPECLYTLPSLRRLNLSSN 243
Score = 45.6 bits (103), Expect = 2e-04
Identities = 30/101 (29%), Positives = 49/101 (48%), Gaps = 2/101 (1%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSV--LPDDLSKLKHLKQLNLDSNKLQALPESLIN 555
+L +P + L L+ L L+ NKL LP + KL +L++ +N L+ +PESL
Sbjct: 267 QLTSLPSAICKLSK-LKKLYLNSNKLDFDGLPSGIGKLTNLEEFMAANNNLELVPESLCR 325
Query: 554 LKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFP 432
KL L ++ N + TLP + L ++ + N P
Sbjct: 326 CPKLRKLVLNKNHLVTLPEAIHFLTEIEVLDVRENPNLVMP 366
>BC014904-1|AAH14904.1| 893|Homo sapiens leucine-rich repeats and
death domain containing protein.
Length = 893
Score = 82.6 bits (195), Expect = 1e-15
Identities = 60/173 (34%), Positives = 92/173 (53%), Gaps = 1/173 (0%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKK 546
L +P + L L +LDLS N L LP + +++ L L L N L LPE+L L
Sbjct: 114 LTNLPAGLSGLAH-LAHLDLSFNSLETLPACVLQMRGLGALLLSHNCLSELPEALGALPA 172
Query: 545 LEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEI 366
L L +++N +QTLP L L+ L+++ S N L P +I GL SL L+L+ N++ +
Sbjct: 173 LTFLTVTHNRLQTLPPALGALSTLQRLDLSQNLLDTLPPEIGGLGSLLELNLASNRLQSL 232
Query: 365 PYGMSELYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLL 210
P ++ L + L L N ++ + DL + P L L L +N L ++ P LL
Sbjct: 233 PASLAGLRSLRLLVLHSNLLASVPADLARLPLLTRLDLRDN--QLRDLPPELL 283
Score = 74.9 bits (176), Expect = 3e-13
Identities = 47/143 (32%), Positives = 75/143 (52%), Gaps = 1/143 (0%)
Frame = -2
Query: 662 KNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTLPVCLKNL 483
+ L+ LP LS L HL L+L N L+ LP ++ ++ L L +S+N + LP L L
Sbjct: 111 RGALTNLPAGLSGLAHLAHLDLSFNSLETLPACVLQMRGLGALLLSHNCLSELPEALGAL 170
Query: 482 NNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSEL-YVIELNLSQNEIS 306
L + ++N+LQ P + L +L LDLS N + +P + L ++ELNL+ N +
Sbjct: 171 PALTFLTVTHNRLQTLPPALGALSTLQRLDLSQNLLDTLPPEIGGLGSLLELNLASNRLQ 230
Query: 305 LIGEDLHQAPRLKILRLDENCLS 237
+ L L++L L N L+
Sbjct: 231 SLPASLAGLRSLRLLVLHSNLLA 253
>AK001637-1|BAA91801.1| 183|Homo sapiens protein ( Homo sapiens
cDNA FLJ10775 fis, clone NT2RP4000312, weakly similar to
ADENYLATE CYCLASE (EC 4.6.1.1). ).
Length = 183
Score = 82.6 bits (195), Expect = 1e-15
Identities = 47/129 (36%), Positives = 80/129 (62%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESL 561
+ D L+ +P ++ +L + L +L+L +N L+ LPD L++L+ L++L+L +N++ LPES+
Sbjct: 54 VNDISLQSLPENIGNLYN-LASLELRENLLTYLPDSLTQLRRLEELDLGNNEIYNLPESI 112
Query: 560 INLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHN 381
L L+ L + N + LP + NL NL + S N+L+ P++I GL SL L +S N
Sbjct: 113 GALLHLKDLWLDGNQLSELPQEIGNLKNLLCLDVSENRLERLPEEISGLTSLTDLVISQN 172
Query: 380 KITEIPYGM 354
+ IP G+
Sbjct: 173 LLETIPDGL 181
Score = 80.2 bits (189), Expect = 7e-15
Identities = 50/164 (30%), Positives = 89/164 (54%), Gaps = 1/164 (0%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
++ EIP + S C L+ D S N L+ LP+ +L++L L+++ LQ+LPE++ NL
Sbjct: 12 EIPEIPESI-SFCKALQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLPENIGNLY 70
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITE 369
L L + N + LP L L L+++ NN++ P+ I L L L L N+++E
Sbjct: 71 NLASLELRENLLTYLPDSLTQLRRLEELDLGNNEIYNLPESIGALLHLKDLWLDGNQLSE 130
Query: 368 IPYGMSEL-YVIELNLSQNEISLIGEDLHQAPRLKILRLDENCL 240
+P + L ++ L++S+N + + E++ L L + +N L
Sbjct: 131 LPQEIGNLKNLLCLDVSENRLERLPEEISGLTSLTDLVISQNLL 174
Score = 79.0 bits (186), Expect = 2e-14
Identities = 49/136 (36%), Positives = 81/136 (59%), Gaps = 4/136 (2%)
Frame = -2
Query: 683 LRNLD-LSKNKLSV--LPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFV 513
L+NL LS N +S+ LP+++ L +L L L N L LP+SL L++LE L++ NN +
Sbjct: 46 LQNLTCLSVNDISLQSLPENIGNLYNLASLELRENLLTYLPDSLTQLRRLEELDLGNNEI 105
Query: 512 QTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSEL-YVI 336
LP + L +LK ++ N+L P++I L++L LD+S N++ +P +S L +
Sbjct: 106 YNLPESIGALLHLKDLWLDGNQLSELPQEIGNLKNLLCLDVSENRLERLPEEISGLTSLT 165
Query: 335 ELNLSQNEISLIGEDL 288
+L +SQN + I + L
Sbjct: 166 DLVISQNLLETIPDGL 181
Score = 77.0 bits (181), Expect = 7e-14
Identities = 46/149 (30%), Positives = 81/149 (54%), Gaps = 1/149 (0%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTL 504
L LD+S+N++ +P+ +S K L+ + N L LPES L+ L L++++ +Q+L
Sbjct: 3 LVELDVSRNEIPEIPESISFCKALQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQSL 62
Query: 503 PVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSE-LYVIELN 327
P + NL NL + N L P + L+ L+ LDL +N+I +P + L++ +L
Sbjct: 63 PENIGNLYNLASLELRENLLTYLPDSLTQLRRLEELDLGNNEIYNLPESIGALLHLKDLW 122
Query: 326 LSQNEISLIGEDLHQAPRLKILRLDENCL 240
L N++S + +++ L L + EN L
Sbjct: 123 LDGNQLSELPQEIGNLKNLLCLDVSENRL 151
Score = 52.8 bits (121), Expect = 1e-06
Identities = 27/66 (40%), Positives = 42/66 (63%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTL 504
L++L L N+LS LP ++ LK+L L++ N+L+ LPE + L L L IS N ++T+
Sbjct: 118 LKDLWLDGNQLSELPQEIGNLKNLLCLDVSENRLERLPEEISGLTSLTDLVISQNLLETI 177
Query: 503 PVCLKN 486
P L+N
Sbjct: 178 PDGLEN 183
>AF274972-1|AAG13461.1| 910|Homo sapiens PIDD protein.
Length = 910
Score = 82.6 bits (195), Expect = 1e-15
Identities = 60/173 (34%), Positives = 92/173 (53%), Gaps = 1/173 (0%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKK 546
L +P + L L +LDLS N L LP + +++ L L L N L LPE+L L
Sbjct: 114 LTNLPAGLSGLAH-LAHLDLSFNSLETLPACVLQMRGLGALLLSHNCLSELPEALGALPA 172
Query: 545 LEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEI 366
L L +++N +QTLP L L+ L+++ S N L P +I GL SL L+L+ N++ +
Sbjct: 173 LTFLTVTHNRLQTLPPALGALSTLQRLDLSQNLLDTLPPEIGGLGSLLELNLASNRLQSL 232
Query: 365 PYGMSELYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLL 210
P ++ L + L L N ++ + DL + P L L L +N L ++ P LL
Sbjct: 233 PASLAGLRSLRLLVLHSNLLASVPADLARLPLLTRLDLRDN--QLRDLPPELL 283
Score = 74.9 bits (176), Expect = 3e-13
Identities = 47/143 (32%), Positives = 75/143 (52%), Gaps = 1/143 (0%)
Frame = -2
Query: 662 KNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTLPVCLKNL 483
+ L+ LP LS L HL L+L N L+ LP ++ ++ L L +S+N + LP L L
Sbjct: 111 RGALTNLPAGLSGLAHLAHLDLSFNSLETLPACVLQMRGLGALLLSHNCLSELPEALGAL 170
Query: 482 NNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSEL-YVIELNLSQNEIS 306
L + ++N+LQ P + L +L LDLS N + +P + L ++ELNL+ N +
Sbjct: 171 PALTFLTVTHNRLQTLPPALGALSTLQRLDLSQNLLDTLPPEIGGLGSLLELNLASNRLQ 230
Query: 305 LIGEDLHQAPRLKILRLDENCLS 237
+ L L++L L N L+
Sbjct: 231 SLPASLAGLRSLRLLVLHSNLLA 253
>BC051322-1|AAH51322.1| 810|Homo sapiens leucine rich repeat
containing 8 family, member A protein.
Length = 810
Score = 82.2 bits (194), Expect = 2e-15
Identities = 46/151 (30%), Positives = 83/151 (54%), Gaps = 3/151 (1%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPE--SLINLKKLEVLNISNNFVQ 510
L L+L + L +P + L +L++++L N L+ + E S +L +L L + N +
Sbjct: 593 LTELELIRCDLERIPHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYNHIA 652
Query: 509 TLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVIE- 333
+P+ + NL NL+++Y + NK++ P Q+ + L LDLSHN +T +P + L ++
Sbjct: 653 YIPIQIGNLTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQN 712
Query: 332 LNLSQNEISLIGEDLHQAPRLKILRLDENCL 240
L ++ N I + +L Q +L+ L L N L
Sbjct: 713 LAITANRIETLPPELFQCRKLRALHLGNNVL 743
Score = 80.2 bits (189), Expect = 7e-15
Identities = 38/102 (37%), Positives = 63/102 (61%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
K+++IP +F C LR LDLS N L+ LP D+ L++L+ L + +N+++ LP L +
Sbjct: 673 KIEKIPTQLF-YCRKLRYLDLSHNNLTFLPADIGLLQNLQNLAITANRIETLPPELFQCR 731
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQI 423
KL L++ NN +Q+LP + L NL Q+ N+L+ P ++
Sbjct: 732 KLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVEL 773
Score = 66.9 bits (156), Expect = 7e-11
Identities = 39/123 (31%), Positives = 68/123 (55%)
Frame = -2
Query: 716 IPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEV 537
IPI + +L + L L L++NK+ +P L + L+ L+L N L LP + L+ L+
Sbjct: 654 IPIQIGNLTN-LERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQN 712
Query: 536 LNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYG 357
L I+ N ++TLP L L+ ++ NN LQ+ P ++ L +L ++L N++ +P
Sbjct: 713 LAITANRIETLPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVE 772
Query: 356 MSE 348
+ E
Sbjct: 773 LGE 775
Score = 49.2 bits (112), Expect = 2e-05
Identities = 49/162 (30%), Positives = 79/162 (48%), Gaps = 9/162 (5%)
Frame = -2
Query: 683 LRNLDLSKN-KLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQT 507
LR L+L+ L L L+K K L L L +P+++ +L +LEVL + T
Sbjct: 402 LRQLNLNNEWTLDKLRQRLTKNAQDK-LELHLFMLSGIPDTVFDLVELEVLKLELIPDVT 460
Query: 506 LPVCLKNLNNLKQ--VYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIP---YGMSELY 342
+P + L LK+ +Y + K++A P ++L L + I EIP Y + L
Sbjct: 461 IPPSIAQLTGLKELWLYHTAAKIEA-PALAFLRENLRALHIKFTDIKEIPLWIYSLKTLE 519
Query: 341 VIEL--NLS-QNEISLIGEDLHQAPRLKILRLDENCLSLDEI 225
+ L NLS +N ++ + L + RLK+LRL N L ++
Sbjct: 520 ELHLTGNLSAENNRYIVIDGLRELKRLKVLRLKSNLSKLPQV 561
Score = 48.4 bits (110), Expect = 3e-05
Identities = 27/83 (32%), Positives = 47/83 (56%)
Frame = -2
Query: 716 IPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEV 537
+P D+ L L+NL ++ N++ LP +L + + L+ L+L +N LQ+LP + L L
Sbjct: 700 LPADI-GLLQNLQNLAITANRIETLPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQ 758
Query: 536 LNISNNFVQTLPVCLKNLNNLKQ 468
+ + N ++ LPV L LK+
Sbjct: 759 IELRGNRLECLPVELGECPLLKR 781
>BC013757-1|AAH13757.1| 403|Homo sapiens LRRC58 protein protein.
Length = 403
Score = 82.2 bits (194), Expect = 2e-15
Identities = 47/130 (36%), Positives = 77/130 (59%), Gaps = 1/130 (0%)
Frame = -2
Query: 695 LCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNF 516
LC L+ L+LS N +P L +L+ L+ L+L N+LQ++P + NL+ LE L + NF
Sbjct: 150 LCRSLQVLNLSGNCFQEVPASLLELRALQTLSLGGNQLQSIPAEIENLQSLECLYLGGNF 209
Query: 515 VQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSEL-YV 339
++ +P L NL +L + +NK+Q+ P Q+ L SL L L +N +T +P + L ++
Sbjct: 210 IKEIPPELGNLPSLNYLVLCDNKIQSIPPQLSQLHSLRSLSLHNNLLTYLPREILNLIHL 269
Query: 338 IELNLSQNEI 309
EL+L N +
Sbjct: 270 EELSLRGNPL 279
Score = 63.7 bits (148), Expect = 7e-10
Identities = 62/202 (30%), Positives = 92/202 (45%), Gaps = 10/202 (4%)
Frame = -2
Query: 689 DVLRNLDLSKNKLSVLPDDL-SKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFV 513
+ L L L N+L LP L S HL+ L++ N L AL L+ L+ L L NN +
Sbjct: 76 EALLRLLLPHNRLVSLPRALGSGFPHLQLLDVSGNALTALGPELLALRGLRTLLAKNNRL 135
Query: 512 ---QTLPVCLKN---LNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMS 351
LP L +L+ + S N Q P +L L++L L L N++ IP +
Sbjct: 136 GGPSALPKGLAQSPLCRSLQVLNLSGNCFQEVPASLLELRALQTLSLGGNQLQSIPAEIE 195
Query: 350 ELYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIHTVSVDG 174
L +E L L N I I +L P L L L +N + I P L + + ++S+
Sbjct: 196 NLQSLECLYLGGNFIKEIPPELGNLPSLNYLVLCDN--KIQSIPPQLSQLHSLRSLSLHN 253
Query: 173 NL--FEPKQLAXLEGYNEYSER 114
NL + P+++ L E S R
Sbjct: 254 NLLTYLPREILNLIHLEELSLR 275
>AY358286-1|AAQ88653.1| 546|Homo sapiens RQTI221 protein.
Length = 546
Score = 82.2 bits (194), Expect = 2e-15
Identities = 46/151 (30%), Positives = 83/151 (54%), Gaps = 3/151 (1%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPE--SLINLKKLEVLNISNNFVQ 510
L L+L + L +P + L +L++++L N L+ + E S +L +L L + N +
Sbjct: 329 LTELELIRCDLERIPHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYNHIA 388
Query: 509 TLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVIE- 333
+P+ + NL NL+++Y + NK++ P Q+ + L LDLSHN +T +P + L ++
Sbjct: 389 YIPIQIGNLTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQN 448
Query: 332 LNLSQNEISLIGEDLHQAPRLKILRLDENCL 240
L ++ N I + +L Q +L+ L L N L
Sbjct: 449 LAITANRIETLPPELFQCRKLRALHLGNNVL 479
Score = 80.2 bits (189), Expect = 7e-15
Identities = 38/102 (37%), Positives = 63/102 (61%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
K+++IP +F C LR LDLS N L+ LP D+ L++L+ L + +N+++ LP L +
Sbjct: 409 KIEKIPTQLF-YCRKLRYLDLSHNNLTFLPADIGLLQNLQNLAITANRIETLPPELFQCR 467
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQI 423
KL L++ NN +Q+LP + L NL Q+ N+L+ P ++
Sbjct: 468 KLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVEL 509
Score = 66.9 bits (156), Expect = 7e-11
Identities = 39/123 (31%), Positives = 68/123 (55%)
Frame = -2
Query: 716 IPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEV 537
IPI + +L + L L L++NK+ +P L + L+ L+L N L LP + L+ L+
Sbjct: 390 IPIQIGNLTN-LERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQN 448
Query: 536 LNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYG 357
L I+ N ++TLP L L+ ++ NN LQ+ P ++ L +L ++L N++ +P
Sbjct: 449 LAITANRIETLPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVE 508
Query: 356 MSE 348
+ E
Sbjct: 509 LGE 511
Score = 49.2 bits (112), Expect = 2e-05
Identities = 49/162 (30%), Positives = 79/162 (48%), Gaps = 9/162 (5%)
Frame = -2
Query: 683 LRNLDLSKN-KLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQT 507
LR L+L+ L L L+K K L L L +P+++ +L +LEVL + T
Sbjct: 138 LRQLNLNNEWTLDKLRQRLTKNAQDK-LELHLFMLSGIPDTVFDLVELEVLKLELIPDVT 196
Query: 506 LPVCLKNLNNLKQ--VYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIP---YGMSELY 342
+P + L LK+ +Y + K++A P ++L L + I EIP Y + L
Sbjct: 197 IPPSIAQLTGLKELWLYHTAAKIEA-PALAFLRENLRALHIKFTDIKEIPLWIYSLKTLE 255
Query: 341 VIEL--NLS-QNEISLIGEDLHQAPRLKILRLDENCLSLDEI 225
+ L NLS +N ++ + L + RLK+LRL N L ++
Sbjct: 256 ELHLTGNLSAENNRYIVIDGLRELKRLKVLRLKSNLSKLPQV 297
Score = 48.4 bits (110), Expect = 3e-05
Identities = 27/83 (32%), Positives = 47/83 (56%)
Frame = -2
Query: 716 IPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEV 537
+P D+ L L+NL ++ N++ LP +L + + L+ L+L +N LQ+LP + L L
Sbjct: 436 LPADI-GLLQNLQNLAITANRIETLPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQ 494
Query: 536 LNISNNFVQTLPVCLKNLNNLKQ 468
+ + N ++ LPV L LK+
Sbjct: 495 IELRGNRLECLPVELGECPLLKR 517
>AY143166-1|AAN18279.1| 810|Homo sapiens leucine-rich
repeat-containing 8 protein.
Length = 810
Score = 82.2 bits (194), Expect = 2e-15
Identities = 46/151 (30%), Positives = 83/151 (54%), Gaps = 3/151 (1%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPE--SLINLKKLEVLNISNNFVQ 510
L L+L + L +P + L +L++++L N L+ + E S +L +L L + N +
Sbjct: 593 LTELELIRCDLERIPHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYNHIA 652
Query: 509 TLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVIE- 333
+P+ + NL NL+++Y + NK++ P Q+ + L LDLSHN +T +P + L ++
Sbjct: 653 YIPIQIGNLTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQN 712
Query: 332 LNLSQNEISLIGEDLHQAPRLKILRLDENCL 240
L ++ N I + +L Q +L+ L L N L
Sbjct: 713 LAITANRIETLPPELFQCRKLRALHLGNNVL 743
Score = 80.2 bits (189), Expect = 7e-15
Identities = 38/102 (37%), Positives = 63/102 (61%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
K+++IP +F C LR LDLS N L+ LP D+ L++L+ L + +N+++ LP L +
Sbjct: 673 KIEKIPTQLF-YCRKLRYLDLSHNNLTFLPADIGLLQNLQNLAITANRIETLPPELFQCR 731
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQI 423
KL L++ NN +Q+LP + L NL Q+ N+L+ P ++
Sbjct: 732 KLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVEL 773
Score = 66.9 bits (156), Expect = 7e-11
Identities = 39/123 (31%), Positives = 68/123 (55%)
Frame = -2
Query: 716 IPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEV 537
IPI + +L + L L L++NK+ +P L + L+ L+L N L LP + L+ L+
Sbjct: 654 IPIQIGNLTN-LERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQN 712
Query: 536 LNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYG 357
L I+ N ++TLP L L+ ++ NN LQ+ P ++ L +L ++L N++ +P
Sbjct: 713 LAITANRIETLPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVE 772
Query: 356 MSE 348
+ E
Sbjct: 773 LGE 775
Score = 49.2 bits (112), Expect = 2e-05
Identities = 49/162 (30%), Positives = 79/162 (48%), Gaps = 9/162 (5%)
Frame = -2
Query: 683 LRNLDLSKN-KLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQT 507
LR L+L+ L L L+K K L L L +P+++ +L +LEVL + T
Sbjct: 402 LRQLNLNNEWTLDKLRQRLTKNAQDK-LELHLFMLSGIPDTVFDLVELEVLKLELIPDVT 460
Query: 506 LPVCLKNLNNLKQ--VYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIP---YGMSELY 342
+P + L LK+ +Y + K++A P ++L L + I EIP Y + L
Sbjct: 461 IPPSIAQLTGLKELWLYHTAAKIEA-PALAFLRENLRALHIKFTDIKEIPLWIYSLKTLE 519
Query: 341 VIEL--NLS-QNEISLIGEDLHQAPRLKILRLDENCLSLDEI 225
+ L NLS +N ++ + L + RLK+LRL N L ++
Sbjct: 520 ELHLTGNLSAENNRYIVIDGLRELKRLKVLRLKSNLSKLPQV 561
Score = 48.4 bits (110), Expect = 3e-05
Identities = 27/83 (32%), Positives = 47/83 (56%)
Frame = -2
Query: 716 IPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEV 537
+P D+ L L+NL ++ N++ LP +L + + L+ L+L +N LQ+LP + L L
Sbjct: 700 LPADI-GLLQNLQNLAITANRIETLPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQ 758
Query: 536 LNISNNFVQTLPVCLKNLNNLKQ 468
+ + N ++ LPV L LK+
Sbjct: 759 IELRGNRLECLPVELGECPLLKR 781
>AL672142-1|CAI10839.1| 810|Homo sapiens leucine rich repeat
containing 8 family, member A protein.
Length = 810
Score = 82.2 bits (194), Expect = 2e-15
Identities = 46/151 (30%), Positives = 83/151 (54%), Gaps = 3/151 (1%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPE--SLINLKKLEVLNISNNFVQ 510
L L+L + L +P + L +L++++L N L+ + E S +L +L L + N +
Sbjct: 593 LTELELIRCDLERIPHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYNHIA 652
Query: 509 TLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVIE- 333
+P+ + NL NL+++Y + NK++ P Q+ + L LDLSHN +T +P + L ++
Sbjct: 653 YIPIQIGNLTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQN 712
Query: 332 LNLSQNEISLIGEDLHQAPRLKILRLDENCL 240
L ++ N I + +L Q +L+ L L N L
Sbjct: 713 LAITANRIETLPPELFQCRKLRALHLGNNVL 743
Score = 80.2 bits (189), Expect = 7e-15
Identities = 38/102 (37%), Positives = 63/102 (61%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
K+++IP +F C LR LDLS N L+ LP D+ L++L+ L + +N+++ LP L +
Sbjct: 673 KIEKIPTQLF-YCRKLRYLDLSHNNLTFLPADIGLLQNLQNLAITANRIETLPPELFQCR 731
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQI 423
KL L++ NN +Q+LP + L NL Q+ N+L+ P ++
Sbjct: 732 KLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVEL 773
Score = 66.9 bits (156), Expect = 7e-11
Identities = 39/123 (31%), Positives = 68/123 (55%)
Frame = -2
Query: 716 IPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEV 537
IPI + +L + L L L++NK+ +P L + L+ L+L N L LP + L+ L+
Sbjct: 654 IPIQIGNLTN-LERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQN 712
Query: 536 LNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYG 357
L I+ N ++TLP L L+ ++ NN LQ+ P ++ L +L ++L N++ +P
Sbjct: 713 LAITANRIETLPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVE 772
Query: 356 MSE 348
+ E
Sbjct: 773 LGE 775
Score = 49.2 bits (112), Expect = 2e-05
Identities = 49/162 (30%), Positives = 79/162 (48%), Gaps = 9/162 (5%)
Frame = -2
Query: 683 LRNLDLSKN-KLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQT 507
LR L+L+ L L L+K K L L L +P+++ +L +LEVL + T
Sbjct: 402 LRQLNLNNEWTLDKLRQRLTKNAQDK-LELHLFMLSGIPDTVFDLVELEVLKLELIPDVT 460
Query: 506 LPVCLKNLNNLKQ--VYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIP---YGMSELY 342
+P + L LK+ +Y + K++A P ++L L + I EIP Y + L
Sbjct: 461 IPPSIAQLTGLKELWLYHTAAKIEA-PALAFLRENLRALHIKFTDIKEIPLWIYSLKTLE 519
Query: 341 VIEL--NLS-QNEISLIGEDLHQAPRLKILRLDENCLSLDEI 225
+ L NLS +N ++ + L + RLK+LRL N L ++
Sbjct: 520 ELHLTGNLSAENNRYIVIDGLRELKRLKVLRLKSNLSKLPQV 561
Score = 48.4 bits (110), Expect = 3e-05
Identities = 27/83 (32%), Positives = 47/83 (56%)
Frame = -2
Query: 716 IPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEV 537
+P D+ L L+NL ++ N++ LP +L + + L+ L+L +N LQ+LP + L L
Sbjct: 700 LPADI-GLLQNLQNLAITANRIETLPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQ 758
Query: 536 LNISNNFVQTLPVCLKNLNNLKQ 468
+ + N ++ LPV L LK+
Sbjct: 759 IELRGNRLECLPVELGECPLLKR 781
>AK074723-1|BAC11161.1| 546|Homo sapiens protein ( Homo sapiens
cDNA FLJ90242 fis, clone NT2RM2001626, highly similar to
Leucine-rich repeat-containing protein 8 precursor. ).
Length = 546
Score = 82.2 bits (194), Expect = 2e-15
Identities = 46/151 (30%), Positives = 83/151 (54%), Gaps = 3/151 (1%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPE--SLINLKKLEVLNISNNFVQ 510
L L+L + L +P + L +L++++L N L+ + E S +L +L L + N +
Sbjct: 329 LTELELIRCDLERIPHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYNHIA 388
Query: 509 TLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVIE- 333
+P+ + NL NL+++Y + NK++ P Q+ + L LDLSHN +T +P + L ++
Sbjct: 389 YIPIQIGNLTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQN 448
Query: 332 LNLSQNEISLIGEDLHQAPRLKILRLDENCL 240
L ++ N I + +L Q +L+ L L N L
Sbjct: 449 LAITANRIETLPPELFQCRKLRALHLGNNVL 479
Score = 78.6 bits (185), Expect = 2e-14
Identities = 37/102 (36%), Positives = 63/102 (61%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
K+++IP +F C LR LDLS N L+ LP D+ L++L+ L + +N+++ LP L +
Sbjct: 409 KIEKIPTQLF-YCRKLRYLDLSHNNLTFLPADIGLLQNLQNLAITANRIETLPPELFQCR 467
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQI 423
KL L++ NN +++LP + L NL Q+ N+L+ P ++
Sbjct: 468 KLRALHLGNNVLRSLPSRVGELTNLTQIELRGNRLECLPVEL 509
Score = 65.3 bits (152), Expect = 2e-10
Identities = 38/123 (30%), Positives = 68/123 (55%)
Frame = -2
Query: 716 IPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEV 537
IPI + +L + L L L++NK+ +P L + L+ L+L N L LP + L+ L+
Sbjct: 390 IPIQIGNLTN-LERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQN 448
Query: 536 LNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYG 357
L I+ N ++TLP L L+ ++ NN L++ P ++ L +L ++L N++ +P
Sbjct: 449 LAITANRIETLPPELFQCRKLRALHLGNNVLRSLPSRVGELTNLTQIELRGNRLECLPVE 508
Query: 356 MSE 348
+ E
Sbjct: 509 LGE 511
Score = 49.2 bits (112), Expect = 2e-05
Identities = 49/162 (30%), Positives = 79/162 (48%), Gaps = 9/162 (5%)
Frame = -2
Query: 683 LRNLDLSKN-KLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQT 507
LR L+L+ L L L+K K L L L +P+++ +L +LEVL + T
Sbjct: 138 LRQLNLNNEWTLDKLRQRLTKNAQDK-LELHLFMLSGIPDTVFDLVELEVLKLELIPDVT 196
Query: 506 LPVCLKNLNNLKQ--VYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIP---YGMSELY 342
+P + L LK+ +Y + K++A P ++L L + I EIP Y + L
Sbjct: 197 IPPSIAQLTGLKELWLYHTAAKIEA-PALAFLRENLRALHIKFTDIKEIPLWIYSLKTLE 255
Query: 341 VIEL--NLS-QNEISLIGEDLHQAPRLKILRLDENCLSLDEI 225
+ L NLS +N ++ + L + RLK+LRL N L ++
Sbjct: 256 ELHLTGNLSAENNRYIVIDGLRELKRLKVLRLKSNLSKLPQV 297
Score = 46.8 bits (106), Expect = 8e-05
Identities = 26/83 (31%), Positives = 47/83 (56%)
Frame = -2
Query: 716 IPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEV 537
+P D+ L L+NL ++ N++ LP +L + + L+ L+L +N L++LP + L L
Sbjct: 436 LPADI-GLLQNLQNLAITANRIETLPPELFQCRKLRALHLGNNVLRSLPSRVGELTNLTQ 494
Query: 536 LNISNNFVQTLPVCLKNLNNLKQ 468
+ + N ++ LPV L LK+
Sbjct: 495 IELRGNRLECLPVELGECPLLKR 517
>AK027495-1|BAB55153.1| 474|Homo sapiens protein ( Homo sapiens
cDNA FLJ14589 fis, clone NT2RM4001876, weakly similar to
RAS SUPPRESSOR PROTEIN 1. ).
Length = 474
Score = 82.2 bits (194), Expect = 2e-15
Identities = 46/151 (30%), Positives = 83/151 (54%), Gaps = 3/151 (1%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPE--SLINLKKLEVLNISNNFVQ 510
L L+L + L +P + L +L++++L N L+ + E S +L +L L + N +
Sbjct: 257 LTELELIRCDLERIPHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYNHIA 316
Query: 509 TLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVIE- 333
+P+ + NL NL+++Y + NK++ P Q+ + L LDLSHN +T +P + L ++
Sbjct: 317 YIPIQIGNLTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQN 376
Query: 332 LNLSQNEISLIGEDLHQAPRLKILRLDENCL 240
L ++ N I + +L Q +L+ L L N L
Sbjct: 377 LAITANRIETLPPELFQCRKLRALHLGNNVL 407
Score = 80.2 bits (189), Expect = 7e-15
Identities = 38/102 (37%), Positives = 63/102 (61%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
K+++IP +F C LR LDLS N L+ LP D+ L++L+ L + +N+++ LP L +
Sbjct: 337 KIEKIPTQLF-YCRKLRYLDLSHNNLTFLPADIGLLQNLQNLAITANRIETLPPELFQCR 395
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQI 423
KL L++ NN +Q+LP + L NL Q+ N+L+ P ++
Sbjct: 396 KLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVEL 437
Score = 66.9 bits (156), Expect = 7e-11
Identities = 39/123 (31%), Positives = 68/123 (55%)
Frame = -2
Query: 716 IPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEV 537
IPI + +L + L L L++NK+ +P L + L+ L+L N L LP + L+ L+
Sbjct: 318 IPIQIGNLTN-LERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQN 376
Query: 536 LNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYG 357
L I+ N ++TLP L L+ ++ NN LQ+ P ++ L +L ++L N++ +P
Sbjct: 377 LAITANRIETLPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVE 436
Query: 356 MSE 348
+ E
Sbjct: 437 LGE 439
Score = 49.2 bits (112), Expect = 2e-05
Identities = 49/162 (30%), Positives = 79/162 (48%), Gaps = 9/162 (5%)
Frame = -2
Query: 683 LRNLDLSKN-KLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQT 507
LR L+L+ L L L+K K L L L +P+++ +L +LEVL + T
Sbjct: 66 LRQLNLNNEWTLDKLRQRLTKNAQDK-LELHLFMLSGIPDTVFDLVELEVLKLELIPDVT 124
Query: 506 LPVCLKNLNNLKQ--VYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIP---YGMSELY 342
+P + L LK+ +Y + K++A P ++L L + I EIP Y + L
Sbjct: 125 IPPSIAQLTGLKELWLYHTAAKIEA-PALAFLRENLRALHIKFTDIKEIPLWIYSLKTLE 183
Query: 341 VIEL--NLS-QNEISLIGEDLHQAPRLKILRLDENCLSLDEI 225
+ L NLS +N ++ + L + RLK+LRL N L ++
Sbjct: 184 ELHLTGNLSAENNRYIVIDGLRELKRLKVLRLKSNLSKLPQV 225
Score = 48.4 bits (110), Expect = 3e-05
Identities = 27/83 (32%), Positives = 47/83 (56%)
Frame = -2
Query: 716 IPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEV 537
+P D+ L L+NL ++ N++ LP +L + + L+ L+L +N LQ+LP + L L
Sbjct: 364 LPADI-GLLQNLQNLAITANRIETLPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQ 422
Query: 536 LNISNNFVQTLPVCLKNLNNLKQ 468
+ + N ++ LPV L LK+
Sbjct: 423 IELRGNRLECLPVELGECPLLKR 445
>AB037858-1|BAA92675.1| 811|Homo sapiens KIAA1437 protein protein.
Length = 811
Score = 82.2 bits (194), Expect = 2e-15
Identities = 46/151 (30%), Positives = 83/151 (54%), Gaps = 3/151 (1%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPE--SLINLKKLEVLNISNNFVQ 510
L L+L + L +P + L +L++++L N L+ + E S +L +L L + N +
Sbjct: 594 LTELELIRCDLERIPHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYNHIA 653
Query: 509 TLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVIE- 333
+P+ + NL NL+++Y + NK++ P Q+ + L LDLSHN +T +P + L ++
Sbjct: 654 YIPIQIGNLTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQN 713
Query: 332 LNLSQNEISLIGEDLHQAPRLKILRLDENCL 240
L ++ N I + +L Q +L+ L L N L
Sbjct: 714 LAITANRIETLPPELFQCRKLRALHLGNNVL 744
Score = 80.2 bits (189), Expect = 7e-15
Identities = 38/102 (37%), Positives = 63/102 (61%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
K+++IP +F C LR LDLS N L+ LP D+ L++L+ L + +N+++ LP L +
Sbjct: 674 KIEKIPTQLF-YCRKLRYLDLSHNNLTFLPADIGLLQNLQNLAITANRIETLPPELFQCR 732
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQI 423
KL L++ NN +Q+LP + L NL Q+ N+L+ P ++
Sbjct: 733 KLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVEL 774
Score = 66.9 bits (156), Expect = 7e-11
Identities = 39/123 (31%), Positives = 68/123 (55%)
Frame = -2
Query: 716 IPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEV 537
IPI + +L + L L L++NK+ +P L + L+ L+L N L LP + L+ L+
Sbjct: 655 IPIQIGNLTN-LERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQN 713
Query: 536 LNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYG 357
L I+ N ++TLP L L+ ++ NN LQ+ P ++ L +L ++L N++ +P
Sbjct: 714 LAITANRIETLPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVE 773
Query: 356 MSE 348
+ E
Sbjct: 774 LGE 776
Score = 49.2 bits (112), Expect = 2e-05
Identities = 49/162 (30%), Positives = 79/162 (48%), Gaps = 9/162 (5%)
Frame = -2
Query: 683 LRNLDLSKN-KLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQT 507
LR L+L+ L L L+K K L L L +P+++ +L +LEVL + T
Sbjct: 403 LRQLNLNNEWTLDKLRQRLTKNAQDK-LELHLFMLSGIPDTVFDLVELEVLKLELIPDVT 461
Query: 506 LPVCLKNLNNLKQ--VYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIP---YGMSELY 342
+P + L LK+ +Y + K++A P ++L L + I EIP Y + L
Sbjct: 462 IPPSIAQLTGLKELWLYHTAAKIEA-PALAFLRENLRALHIKFTDIKEIPLWIYSLKTLE 520
Query: 341 VIEL--NLS-QNEISLIGEDLHQAPRLKILRLDENCLSLDEI 225
+ L NLS +N ++ + L + RLK+LRL N L ++
Sbjct: 521 ELHLTGNLSAENNRYIVIDGLRELKRLKVLRLKSNLSKLPQV 562
Score = 48.4 bits (110), Expect = 3e-05
Identities = 27/83 (32%), Positives = 47/83 (56%)
Frame = -2
Query: 716 IPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEV 537
+P D+ L L+NL ++ N++ LP +L + + L+ L+L +N LQ+LP + L L
Sbjct: 701 LPADI-GLLQNLQNLAITANRIETLPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQ 759
Query: 536 LNISNNFVQTLPVCLKNLNNLKQ 468
+ + N ++ LPV L LK+
Sbjct: 760 IELRGNRLECLPVELGECPLLKR 782
>AY358137-1|AAQ88504.1| 255|Homo sapiens VKGE9338 protein.
Length = 255
Score = 81.8 bits (193), Expect = 2e-15
Identities = 51/143 (35%), Positives = 80/143 (55%), Gaps = 3/143 (2%)
Frame = -2
Query: 713 PIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVL 534
P + L D + LDLS+N + +PD +SK ++L+ L+L SN + LPES+ + L L
Sbjct: 43 PKCILRLSD-MDELDLSRNLIRKIPDSISKFQNLRWLDLHSNYIDKLPESIGQMTSLLYL 101
Query: 533 NISNNFVQT--LPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPY 360
N+SNN + + LPV LK L N++ V N L + P + L+ L + L N + IP
Sbjct: 102 NVSNNRLTSNGLPVELKQLKNIRAVNLGLNHLDSVPTTLGALKELHEVGLHDNLLNNIPV 161
Query: 359 GMSELYVI-ELNLSQNEISLIGE 294
+S+L + +LN+ +N GE
Sbjct: 162 SISKLPKLKKLNIKRNPFPKPGE 184
Score = 69.3 bits (162), Expect = 1e-11
Identities = 38/151 (25%), Positives = 80/151 (52%), Gaps = 3/151 (1%)
Frame = -2
Query: 689 DVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQ 510
D + LDLSK ++ P + +L + +L+L N ++ +P+S+ + L L++ +N++
Sbjct: 27 DGKKRLDLSKMGITTFPKCILRLSDMDELDLSRNLIRKIPDSISKFQNLRWLDLHSNYID 86
Query: 509 TLPVCLKNLNNLKQVYASNNKL--QAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVI 336
LP + + +L + SNN+L P ++ L+++ ++L N + +P + L +
Sbjct: 87 KLPESIGQMTSLLYLNVSNNRLTSNGLPVELKQLKNIRAVNLGLNHLDSVPTTLGALKEL 146
Query: 335 -ELNLSQNEISLIGEDLHQAPRLKILRLDEN 246
E+ L N ++ I + + P+LK L + N
Sbjct: 147 HEVGLHDNLLNNIPVSISKLPKLKKLNIKRN 177
Score = 33.1 bits (72), Expect = 1.1
Identities = 31/111 (27%), Positives = 51/111 (45%), Gaps = 10/111 (9%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLI---N 555
L +P + +L + L + L N L+ +P +SKL LK+LN+ N ES I +
Sbjct: 133 LDSVPTTLGALKE-LHEVGLHDNLLNNIPVSISKLPKLKKLNIKRNPFPKPGESEIFIDS 191
Query: 554 LKKLEVLNISNNFVQTLPVCLK-------NLNNLKQVYASNNKLQAFPKQI 423
+++LE L + CL+ NLN +K + + + FP I
Sbjct: 192 IRRLENLYVVEE-KDLCAACLRKCQNARDNLNRIKNMATTTPRKTIFPNLI 241
>AK021896-1|BAB13929.1| 197|Homo sapiens protein ( Homo sapiens
cDNA FLJ11834 fis, clone HEMBA1006583, weakly similar to
Drosophila melanogaster Scribble (scrib) mRNA. ).
Length = 197
Score = 81.4 bits (192), Expect = 3e-15
Identities = 49/176 (27%), Positives = 88/176 (50%), Gaps = 2/176 (1%)
Frame = -2
Query: 731 CKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINL 552
C L +P +++ L L L N+L LP+ +L L++L L N++Q LP + N
Sbjct: 22 CSLVYVPEEIYRYARSLEELLLDANQLRELPEQFFQLVKLRKLGLSDNEIQRLPPEIANF 81
Query: 551 KKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKIT 372
+L L++S N + +P + L+ S N L P+ LQ+L L ++ +
Sbjct: 82 MQLVELDVSRNEIPEIPESISFCKALQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQ 141
Query: 371 EIPYGMSELY-VIELNLSQNEISLIGEDLHQAPRLKILRLDEN-CLSLDEIKPSLL 210
+P + LY + L L +N ++ + + L Q RL+ L L N +L++++PS +
Sbjct: 142 SLPENIGNLYNLASLELRENLLTYLPDSLTQLRRLEELDLGNNEIYNLNQLEPSYI 197
>AL391728-3|CAH73693.1| 217|Homo sapiens leucine rich repeat
containing 7 protein.
Length = 217
Score = 80.6 bits (190), Expect = 5e-15
Identities = 46/152 (30%), Positives = 88/152 (57%), Gaps = 2/152 (1%)
Frame = -2
Query: 689 DVLRNLDLSKNKLSVLPDDLSKLKH-LKQLNLDSNKLQALPESLINLKKLEVLNISNNFV 513
+++ LD S L +P ++ + L++L LD+N+++ LP+ L N + L L+I +N +
Sbjct: 60 EIISVLDYSHCSLQQVPKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDL 119
Query: 512 QTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELY-VI 336
LP + +L NLK++ S N +Q FP+ I + L +++ S N I+++P G ++L +
Sbjct: 120 SNLPTTIASLVNLKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLT 179
Query: 335 ELNLSQNEISLIGEDLHQAPRLKILRLDENCL 240
+L L+ + + + + +L+IL L EN L
Sbjct: 180 QLYLNDAFLEFLPANFGRLVKLRILELRENHL 211
Score = 70.5 bits (165), Expect = 6e-12
Identities = 39/122 (31%), Positives = 66/122 (54%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
+++E+P +F+ C LR L + N LS LP ++ L +LK+L++ N +Q PE++ K
Sbjct: 95 QIEELPKQLFN-CQALRKLSIPDNDLSNLPTTIASLVNLKELDISKNGVQEFPENIKCCK 153
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITE 369
L ++ S N + LP L NL Q+Y ++ L+ P L L +L+L N +
Sbjct: 154 CLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRENHLKT 213
Query: 368 IP 363
+P
Sbjct: 214 LP 215
Score = 64.9 bits (151), Expect = 3e-10
Identities = 42/145 (28%), Positives = 70/145 (48%), Gaps = 1/145 (0%)
Frame = -2
Query: 731 CKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINL 552
C L+++P +VF+ L L L N++ LP L + L++L++ N L LP ++ +L
Sbjct: 70 CSLQQVPKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASL 129
Query: 551 KKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKIT 372
L+ L+IS N VQ P +K L + AS N + P L +L L L+ +
Sbjct: 130 VNLKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLE 189
Query: 371 EIPYGMSELYVIE-LNLSQNEISLI 300
+P L + L L +N + +
Sbjct: 190 FLPANFGRLVKLRILELRENHLKTL 214
>AL359894-1|CAH73131.1| 217|Homo sapiens leucine rich repeat
containing 7 protein.
Length = 217
Score = 80.6 bits (190), Expect = 5e-15
Identities = 46/152 (30%), Positives = 88/152 (57%), Gaps = 2/152 (1%)
Frame = -2
Query: 689 DVLRNLDLSKNKLSVLPDDLSKLKH-LKQLNLDSNKLQALPESLINLKKLEVLNISNNFV 513
+++ LD S L +P ++ + L++L LD+N+++ LP+ L N + L L+I +N +
Sbjct: 60 EIISVLDYSHCSLQQVPKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDL 119
Query: 512 QTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELY-VI 336
LP + +L NLK++ S N +Q FP+ I + L +++ S N I+++P G ++L +
Sbjct: 120 SNLPTTIASLVNLKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLT 179
Query: 335 ELNLSQNEISLIGEDLHQAPRLKILRLDENCL 240
+L L+ + + + + +L+IL L EN L
Sbjct: 180 QLYLNDAFLEFLPANFGRLVKLRILELRENHL 211
Score = 70.5 bits (165), Expect = 6e-12
Identities = 39/122 (31%), Positives = 66/122 (54%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
+++E+P +F+ C LR L + N LS LP ++ L +LK+L++ N +Q PE++ K
Sbjct: 95 QIEELPKQLFN-CQALRKLSIPDNDLSNLPTTIASLVNLKELDISKNGVQEFPENIKCCK 153
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITE 369
L ++ S N + LP L NL Q+Y ++ L+ P L L +L+L N +
Sbjct: 154 CLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRENHLKT 213
Query: 368 IP 363
+P
Sbjct: 214 LP 215
Score = 64.9 bits (151), Expect = 3e-10
Identities = 42/145 (28%), Positives = 70/145 (48%), Gaps = 1/145 (0%)
Frame = -2
Query: 731 CKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINL 552
C L+++P +VF+ L L L N++ LP L + L++L++ N L LP ++ +L
Sbjct: 70 CSLQQVPKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASL 129
Query: 551 KKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKIT 372
L+ L+IS N VQ P +K L + AS N + P L +L L L+ +
Sbjct: 130 VNLKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLE 189
Query: 371 EIPYGMSELYVIE-LNLSQNEISLI 300
+P L + L L +N + +
Sbjct: 190 FLPANFGRLVKLRILELRENHLKTL 214
>AL359412-3|CAH74020.1| 217|Homo sapiens leucine rich repeat
containing 7 protein.
Length = 217
Score = 80.6 bits (190), Expect = 5e-15
Identities = 46/152 (30%), Positives = 88/152 (57%), Gaps = 2/152 (1%)
Frame = -2
Query: 689 DVLRNLDLSKNKLSVLPDDLSKLKH-LKQLNLDSNKLQALPESLINLKKLEVLNISNNFV 513
+++ LD S L +P ++ + L++L LD+N+++ LP+ L N + L L+I +N +
Sbjct: 60 EIISVLDYSHCSLQQVPKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDL 119
Query: 512 QTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELY-VI 336
LP + +L NLK++ S N +Q FP+ I + L +++ S N I+++P G ++L +
Sbjct: 120 SNLPTTIASLVNLKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLT 179
Query: 335 ELNLSQNEISLIGEDLHQAPRLKILRLDENCL 240
+L L+ + + + + +L+IL L EN L
Sbjct: 180 QLYLNDAFLEFLPANFGRLVKLRILELRENHL 211
Score = 70.5 bits (165), Expect = 6e-12
Identities = 39/122 (31%), Positives = 66/122 (54%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
+++E+P +F+ C LR L + N LS LP ++ L +LK+L++ N +Q PE++ K
Sbjct: 95 QIEELPKQLFN-CQALRKLSIPDNDLSNLPTTIASLVNLKELDISKNGVQEFPENIKCCK 153
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITE 369
L ++ S N + LP L NL Q+Y ++ L+ P L L +L+L N +
Sbjct: 154 CLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRENHLKT 213
Query: 368 IP 363
+P
Sbjct: 214 LP 215
Score = 64.9 bits (151), Expect = 3e-10
Identities = 42/145 (28%), Positives = 70/145 (48%), Gaps = 1/145 (0%)
Frame = -2
Query: 731 CKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINL 552
C L+++P +VF+ L L L N++ LP L + L++L++ N L LP ++ +L
Sbjct: 70 CSLQQVPKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASL 129
Query: 551 KKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKIT 372
L+ L+IS N VQ P +K L + AS N + P L +L L L+ +
Sbjct: 130 VNLKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLE 189
Query: 371 EIPYGMSELYVIE-LNLSQNEISLI 300
+P L + L L +N + +
Sbjct: 190 FLPANFGRLVKLRILELRENHLKTL 214
>AL117353-2|CAI23424.1| 217|Homo sapiens leucine rich repeat
containing 7 protein.
Length = 217
Score = 80.6 bits (190), Expect = 5e-15
Identities = 46/152 (30%), Positives = 88/152 (57%), Gaps = 2/152 (1%)
Frame = -2
Query: 689 DVLRNLDLSKNKLSVLPDDLSKLKH-LKQLNLDSNKLQALPESLINLKKLEVLNISNNFV 513
+++ LD S L +P ++ + L++L LD+N+++ LP+ L N + L L+I +N +
Sbjct: 60 EIISVLDYSHCSLQQVPKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDL 119
Query: 512 QTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELY-VI 336
LP + +L NLK++ S N +Q FP+ I + L +++ S N I+++P G ++L +
Sbjct: 120 SNLPTTIASLVNLKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLT 179
Query: 335 ELNLSQNEISLIGEDLHQAPRLKILRLDENCL 240
+L L+ + + + + +L+IL L EN L
Sbjct: 180 QLYLNDAFLEFLPANFGRLVKLRILELRENHL 211
Score = 70.5 bits (165), Expect = 6e-12
Identities = 39/122 (31%), Positives = 66/122 (54%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
+++E+P +F+ C LR L + N LS LP ++ L +LK+L++ N +Q PE++ K
Sbjct: 95 QIEELPKQLFN-CQALRKLSIPDNDLSNLPTTIASLVNLKELDISKNGVQEFPENIKCCK 153
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITE 369
L ++ S N + LP L NL Q+Y ++ L+ P L L +L+L N +
Sbjct: 154 CLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRENHLKT 213
Query: 368 IP 363
+P
Sbjct: 214 LP 215
Score = 64.9 bits (151), Expect = 3e-10
Identities = 42/145 (28%), Positives = 70/145 (48%), Gaps = 1/145 (0%)
Frame = -2
Query: 731 CKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINL 552
C L+++P +VF+ L L L N++ LP L + L++L++ N L LP ++ +L
Sbjct: 70 CSLQQVPKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASL 129
Query: 551 KKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKIT 372
L+ L+IS N VQ P +K L + AS N + P L +L L L+ +
Sbjct: 130 VNLKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLE 189
Query: 371 EIPYGMSELYVIE-LNLSQNEISLI 300
+P L + L L +N + +
Sbjct: 190 FLPANFGRLVKLRILELRENHLKTL 214
>AF498274-1|AAP06801.1| 217|Homo sapiens densin-180 like protein
protein.
Length = 217
Score = 80.6 bits (190), Expect = 5e-15
Identities = 46/152 (30%), Positives = 88/152 (57%), Gaps = 2/152 (1%)
Frame = -2
Query: 689 DVLRNLDLSKNKLSVLPDDLSKLKH-LKQLNLDSNKLQALPESLINLKKLEVLNISNNFV 513
+++ LD S L +P ++ + L++L LD+N+++ LP+ L N + L L+I +N +
Sbjct: 60 EIISVLDYSHCSLQQVPKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDL 119
Query: 512 QTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELY-VI 336
LP + +L NLK++ S N +Q FP+ I + L +++ S N I+++P G ++L +
Sbjct: 120 SNLPTTIASLVNLKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLT 179
Query: 335 ELNLSQNEISLIGEDLHQAPRLKILRLDENCL 240
+L L+ + + + + +L+IL L EN L
Sbjct: 180 QLYLNDAFLEFLPANFGRLVKLRILELRENHL 211
Score = 70.5 bits (165), Expect = 6e-12
Identities = 39/122 (31%), Positives = 66/122 (54%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
+++E+P +F+ C LR L + N LS LP ++ L +LK+L++ N +Q PE++ K
Sbjct: 95 QIEELPKQLFN-CQALRKLSIPDNDLSNLPTTIASLVNLKELDISKNGVQEFPENIKCCK 153
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITE 369
L ++ S N + LP L NL Q+Y ++ L+ P L L +L+L N +
Sbjct: 154 CLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRENHLKT 213
Query: 368 IP 363
+P
Sbjct: 214 LP 215
Score = 64.9 bits (151), Expect = 3e-10
Identities = 42/145 (28%), Positives = 70/145 (48%), Gaps = 1/145 (0%)
Frame = -2
Query: 731 CKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINL 552
C L+++P +VF+ L L L N++ LP L + L++L++ N L LP ++ +L
Sbjct: 70 CSLQQVPKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASL 129
Query: 551 KKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKIT 372
L+ L+IS N VQ P +K L + AS N + P L +L L L+ +
Sbjct: 130 VNLKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLE 189
Query: 371 EIPYGMSELYVIE-LNLSQNEISLI 300
+P L + L L +N + +
Sbjct: 190 FLPANFGRLVKLRILELRENHLKTL 214
>BC029118-1|AAH29118.1| 371|Homo sapiens leucine rich repeat
containing 2 protein.
Length = 371
Score = 80.2 bits (189), Expect = 7e-15
Identities = 51/162 (31%), Positives = 91/162 (56%), Gaps = 2/162 (1%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESL 561
I++ ++ IP + L +R LDL KN++S LP ++ LK+LK+LN+ N L+++P L
Sbjct: 128 ISNTLIQIIPTYI-QLFQAMRILDLPKNQISHLPAEIGCLKNLKELNVGFNYLKSIPPEL 186
Query: 560 INLKKLEVLNISNNF-VQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSH 384
+ + LE L+ S N + LP L NL + V S NK + P +L + +L LD+S
Sbjct: 187 GDCENLERLDCSGNLELMELPFELSNLKQVTFVDISANKFSSVPICVLRMSNLQWLDISS 246
Query: 383 NKITEIPYGMSELYVIE-LNLSQNEISLIGEDLHQAPRLKIL 261
N +T++P + L ++ L +N+++ + + +L +L
Sbjct: 247 NNLTDLPQDIDRLEELQSFLLYKNKLTYLPYSMLNLKKLTLL 288
Score = 67.7 bits (158), Expect = 4e-11
Identities = 40/127 (31%), Positives = 70/127 (55%), Gaps = 1/127 (0%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKN-KLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
LK IP ++ C+ L LD S N +L LP +LS LK + +++ +NK ++P ++ +
Sbjct: 179 LKSIPPELGD-CENLERLDCSGNLELMELPFELSNLKQVTFVDISANKFSSVPICVLRMS 237
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITE 369
L+ L+IS+N + LP + L L+ NKL P +L L+ L +L +S + + E
Sbjct: 238 NLQWLDISSNNLTDLPQDIDRLEELQSFLLYKNKLTYLPYSMLNLKKLTLLVVSGDHLVE 297
Query: 368 IPYGMSE 348
+P + +
Sbjct: 298 LPTALCD 304
Score = 67.3 bits (157), Expect = 5e-11
Identities = 42/173 (24%), Positives = 93/173 (53%), Gaps = 2/173 (1%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTL 504
LR +S + ++P + + ++ L+L N++ LP + LK L+ LN+ N+++++
Sbjct: 123 LREWYISNTLIQIIPTYIQLFQAMRILDLPKNQISHLPAEIGCLKNLKELNVGFNYLKSI 182
Query: 503 PVCLKNLNNLKQVYASNN-KLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVIE-L 330
P L + NL+++ S N +L P ++ L+ + +D+S NK + +P + + ++ L
Sbjct: 183 PPELGDCENLERLDCSGNLELMELPFELSNLKQVTFVDISANKFSSVPICVLRMSNLQWL 242
Query: 329 NLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIHTVSVDGN 171
++S N ++ + +D+ + L+ L +N L + S+L K+ + V G+
Sbjct: 243 DISSNNLTDLPQDIDRLEELQSFLLYKN--KLTYLPYSMLNLKKLTLLVVSGD 293
Score = 61.7 bits (143), Expect = 3e-09
Identities = 38/147 (25%), Positives = 79/147 (53%), Gaps = 2/147 (1%)
Frame = -2
Query: 671 DLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTLPVCL 492
+LS + LPD L + HL++ + + +Q +P + + + +L++ N + LP +
Sbjct: 104 ELSGEHWTELPDSLKEQTHLREWYISNTLIQIIPTYIQLFQAMRILDLPKNQISHLPAEI 163
Query: 491 KNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHN-KITEIPYGMSEL-YVIELNLSQ 318
L NLK++ N L++ P ++ ++L+ LD S N ++ E+P+ +S L V +++S
Sbjct: 164 GCLKNLKELNVGFNYLKSIPPELGDCENLERLDCSGNLELMELPFELSNLKQVTFVDISA 223
Query: 317 NEISLIGEDLHQAPRLKILRLDENCLS 237
N+ S + + + L+ L + N L+
Sbjct: 224 NKFSSVPICVLRMSNLQWLDISSNNLT 250
Score = 46.8 bits (106), Expect = 8e-05
Identities = 49/200 (24%), Positives = 88/200 (44%), Gaps = 10/200 (5%)
Frame = -2
Query: 740 IADCKLKEIPIDVF---SLCDV-LRNLD-LSKNKL---SVLPDDLSKLKHLKQLNLDSNK 585
+A+C+ K IP V+ D +R LD + +N L S LP D K L
Sbjct: 50 VAECRRKGIPQAVYCKNGFIDTSVRLLDKIERNTLTRQSSLPKDRGKRSSAFVFELSGEH 109
Query: 584 LQALPESLINLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSL 405
LP+SL L ISN +Q +P ++ ++ + N++ P +I L++L
Sbjct: 110 WTELPDSLKEQTHLREWYISNTLIQIIPTYIQLFQAMRILDLPKNQISHLPAEIGCLKNL 169
Query: 404 DVLDLSHNKITEIPYGMSELYVIE-LNLSQN-EISLIGEDLHQAPRLKILRLDENCLSLD 231
L++ N + IP + + +E L+ S N E+ + +L ++ + + N S
Sbjct: 170 KELNVGFNYLKSIPPELGDCENLERLDCSGNLELMELPFELSNLKQVTFVDISANKFS-- 227
Query: 230 EIKPSLLRDSKIHTVSVDGN 171
+ +LR S + + + N
Sbjct: 228 SVPICVLRMSNLQWLDISSN 247
>AK223440-1|BAD97160.1| 371|Homo sapiens leucine rich repeat
containing 2 variant protein.
Length = 371
Score = 80.2 bits (189), Expect = 7e-15
Identities = 51/162 (31%), Positives = 91/162 (56%), Gaps = 2/162 (1%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESL 561
I++ ++ IP + L +R LDL KN++S LP ++ LK+LK+LN+ N L+++P L
Sbjct: 128 ISNTLIQIIPTYI-QLFQAMRILDLPKNQISHLPAEIGCLKNLKELNVGFNYLKSIPPEL 186
Query: 560 INLKKLEVLNISNNF-VQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSH 384
+ + LE L+ S N + LP L NL + V S NK + P +L + +L LD+S
Sbjct: 187 GDCENLERLDCSGNLELMELPFELSNLKQVTFVDISANKFSSVPICVLRMSNLQWLDISS 246
Query: 383 NKITEIPYGMSELYVIE-LNLSQNEISLIGEDLHQAPRLKIL 261
N +T++P + L ++ L +N+++ + + +L +L
Sbjct: 247 NNLTDLPQDIDRLEELQSFLLYKNKLTYLPYSMLNLKKLTLL 288
Score = 67.7 bits (158), Expect = 4e-11
Identities = 40/127 (31%), Positives = 70/127 (55%), Gaps = 1/127 (0%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKN-KLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
LK IP ++ C+ L LD S N +L LP +LS LK + +++ +NK ++P ++ +
Sbjct: 179 LKSIPPELGD-CENLERLDCSGNLELMELPFELSNLKQVTFVDISANKFSSVPICVLRMS 237
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITE 369
L+ L+IS+N + LP + L L+ NKL P +L L+ L +L +S + + E
Sbjct: 238 NLQWLDISSNNLTDLPQDIDRLEELQSFLLYKNKLTYLPYSMLNLKKLTLLVVSGDHLVE 297
Query: 368 IPYGMSE 348
+P + +
Sbjct: 298 LPTALCD 304
Score = 67.3 bits (157), Expect = 5e-11
Identities = 42/173 (24%), Positives = 93/173 (53%), Gaps = 2/173 (1%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTL 504
LR +S + ++P + + ++ L+L N++ LP + LK L+ LN+ N+++++
Sbjct: 123 LREWYISNTLIQIIPTYIQLFQAMRILDLPKNQISHLPAEIGCLKNLKELNVGFNYLKSI 182
Query: 503 PVCLKNLNNLKQVYASNN-KLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVIE-L 330
P L + NL+++ S N +L P ++ L+ + +D+S NK + +P + + ++ L
Sbjct: 183 PPELGDCENLERLDCSGNLELMELPFELSNLKQVTFVDISANKFSSVPICVLRMSNLQWL 242
Query: 329 NLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIHTVSVDGN 171
++S N ++ + +D+ + L+ L +N L + S+L K+ + V G+
Sbjct: 243 DISSNNLTDLPQDIDRLEELQSFLLYKN--KLTYLPYSMLNLKKLTLLVVSGD 293
Score = 61.7 bits (143), Expect = 3e-09
Identities = 38/147 (25%), Positives = 79/147 (53%), Gaps = 2/147 (1%)
Frame = -2
Query: 671 DLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTLPVCL 492
+LS + LPD L + HL++ + + +Q +P + + + +L++ N + LP +
Sbjct: 104 ELSGEHWTELPDSLKEQTHLREWYISNTLIQIIPTYIQLFQAMRILDLPKNQISHLPAEI 163
Query: 491 KNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHN-KITEIPYGMSEL-YVIELNLSQ 318
L NLK++ N L++ P ++ ++L+ LD S N ++ E+P+ +S L V +++S
Sbjct: 164 GCLKNLKELNVGFNYLKSIPPELGDCENLERLDCSGNLELMELPFELSNLKQVTFVDISA 223
Query: 317 NEISLIGEDLHQAPRLKILRLDENCLS 237
N+ S + + + L+ L + N L+
Sbjct: 224 NKFSSVPICVLRMSNLQWLDISSNNLT 250
Score = 46.8 bits (106), Expect = 8e-05
Identities = 49/200 (24%), Positives = 88/200 (44%), Gaps = 10/200 (5%)
Frame = -2
Query: 740 IADCKLKEIPIDVF---SLCDV-LRNLD-LSKNKL---SVLPDDLSKLKHLKQLNLDSNK 585
+A+C+ K IP V+ D +R LD + +N L S LP D K L
Sbjct: 50 VAECRRKGIPQAVYCKNGFIDTSVRLLDKIERNTLTRQSSLPKDRGKRSSAFVFELSGEH 109
Query: 584 LQALPESLINLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSL 405
LP+SL L ISN +Q +P ++ ++ + N++ P +I L++L
Sbjct: 110 WTELPDSLKEQTHLREWYISNTLIQIIPTYIQLFQAMRILDLPKNQISHLPAEIGCLKNL 169
Query: 404 DVLDLSHNKITEIPYGMSELYVIE-LNLSQN-EISLIGEDLHQAPRLKILRLDENCLSLD 231
L++ N + IP + + +E L+ S N E+ + +L ++ + + N S
Sbjct: 170 KELNVGFNYLKSIPPELGDCENLERLDCSGNLELMELPFELSNLKQVTFVDISANKFS-- 227
Query: 230 EIKPSLLRDSKIHTVSVDGN 171
+ +LR S + + + N
Sbjct: 228 SVPICVLRMSNLQWLDISSN 247
>AK057808-1|BAB71585.1| 371|Homo sapiens protein ( Homo sapiens
cDNA FLJ25079 fis, clone CBL07055. ).
Length = 371
Score = 80.2 bits (189), Expect = 7e-15
Identities = 51/162 (31%), Positives = 91/162 (56%), Gaps = 2/162 (1%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESL 561
I++ ++ IP + L +R LDL KN++S LP ++ LK+LK+LN+ N L+++P L
Sbjct: 128 ISNTLIQIIPTYI-QLFQAMRILDLPKNQISHLPAEIGCLKNLKELNVGFNYLKSIPPEL 186
Query: 560 INLKKLEVLNISNNF-VQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSH 384
+ + LE L+ S N + LP L NL + V S NK + P +L + +L LD+S
Sbjct: 187 GDCENLERLDCSGNLELMELPFELSNLKQVTFVDISANKFSSVPICVLRMSNLQWLDISS 246
Query: 383 NKITEIPYGMSELYVIE-LNLSQNEISLIGEDLHQAPRLKIL 261
N +T++P + L ++ L +N+++ + + +L +L
Sbjct: 247 NNLTDLPQDIDRLEELQSFLLYKNKLTYLPYSMLNLKKLTLL 288
Score = 67.7 bits (158), Expect = 4e-11
Identities = 40/127 (31%), Positives = 70/127 (55%), Gaps = 1/127 (0%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKN-KLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
LK IP ++ C+ L LD S N +L LP +LS LK + +++ +NK ++P ++ +
Sbjct: 179 LKSIPPELGD-CENLERLDCSGNLELMELPFELSNLKQVTFVDISANKFSSVPICVLRMS 237
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITE 369
L+ L+IS+N + LP + L L+ NKL P +L L+ L +L +S + + E
Sbjct: 238 NLQWLDISSNNLTDLPQDIDRLEELQSFLLYKNKLTYLPYSMLNLKKLTLLVVSGDHLVE 297
Query: 368 IPYGMSE 348
+P + +
Sbjct: 298 LPTALCD 304
Score = 67.3 bits (157), Expect = 5e-11
Identities = 42/173 (24%), Positives = 93/173 (53%), Gaps = 2/173 (1%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTL 504
LR +S + ++P + + ++ L+L N++ LP + LK L+ LN+ N+++++
Sbjct: 123 LREWYISNTLIQIIPTYIQLFQAMRILDLPKNQISHLPAEIGCLKNLKELNVGFNYLKSI 182
Query: 503 PVCLKNLNNLKQVYASNN-KLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVIE-L 330
P L + NL+++ S N +L P ++ L+ + +D+S NK + +P + + ++ L
Sbjct: 183 PPELGDCENLERLDCSGNLELMELPFELSNLKQVTFVDISANKFSSVPICVLRMSNLQWL 242
Query: 329 NLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIHTVSVDGN 171
++S N ++ + +D+ + L+ L +N L + S+L K+ + V G+
Sbjct: 243 DISSNNLTDLPQDIDRLEELQSFLLYKN--KLTYLPYSMLNLKKLTLLVVSGD 293
Score = 61.7 bits (143), Expect = 3e-09
Identities = 38/147 (25%), Positives = 79/147 (53%), Gaps = 2/147 (1%)
Frame = -2
Query: 671 DLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTLPVCL 492
+LS + LPD L + HL++ + + +Q +P + + + +L++ N + LP +
Sbjct: 104 ELSGEHWTELPDSLKEQTHLREWYISNTLIQIIPTYIQLFQAMRILDLPKNQISHLPAEI 163
Query: 491 KNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHN-KITEIPYGMSEL-YVIELNLSQ 318
L NLK++ N L++ P ++ ++L+ LD S N ++ E+P+ +S L V +++S
Sbjct: 164 GCLKNLKELNVGFNYLKSIPPELGDCENLERLDCSGNLELMELPFELSNLKQVTFVDISA 223
Query: 317 NEISLIGEDLHQAPRLKILRLDENCLS 237
N+ S + + + L+ L + N L+
Sbjct: 224 NKFSSVPICVLRMSNLQWLDISSNNLT 250
Score = 46.8 bits (106), Expect = 8e-05
Identities = 49/200 (24%), Positives = 88/200 (44%), Gaps = 10/200 (5%)
Frame = -2
Query: 740 IADCKLKEIPIDVF---SLCDV-LRNLD-LSKNKL---SVLPDDLSKLKHLKQLNLDSNK 585
+A+C+ K IP V+ D +R LD + +N L S LP D K L
Sbjct: 50 VAECRRKGIPQAVYCKNGFIDTSVRLLDKIERNTLTRQSSLPKDRGKRSSAFVFELSGEH 109
Query: 584 LQALPESLINLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSL 405
LP+SL L ISN +Q +P ++ ++ + N++ P +I L++L
Sbjct: 110 WTELPDSLKEQTHLREWYISNTLIQIIPTYIQLFQAMRILDLPKNQISHLPAEIGCLKNL 169
Query: 404 DVLDLSHNKITEIPYGMSELYVIE-LNLSQN-EISLIGEDLHQAPRLKILRLDENCLSLD 231
L++ N + IP + + +E L+ S N E+ + +L ++ + + N S
Sbjct: 170 KELNVGFNYLKSIPPELGDCENLERLDCSGNLELMELPFELSNLKQVTFVDISANKFS-- 227
Query: 230 EIKPSLLRDSKIHTVSVDGN 171
+ +LR S + + + N
Sbjct: 228 SVPICVLRMSNLQWLDISSN 247
>AK001199-1|BAA91549.1| 221|Homo sapiens protein ( Homo sapiens
cDNA FLJ10337 fis, clone NT2RM2000714, weakly similar to
RAS SUPPRESSOR PROTEIN 1. ).
Length = 221
Score = 80.2 bits (189), Expect = 7e-15
Identities = 45/151 (29%), Positives = 83/151 (54%), Gaps = 3/151 (1%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPE--SLINLKKLEVLNISNNFVQ 510
L L+L + L +P + L +L++++L + L+ + E S +L +L L + N +
Sbjct: 4 LTELELIRCDLERIPHSIFSLHNLQEIDLKDDNLKTIEEIISFQHLHRLTCLKLWYNHIA 63
Query: 509 TLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVIE- 333
+P+ + NL NL+++Y + NK++ P Q+ + L LDLSHN +T +P + L ++
Sbjct: 64 YIPIQIGNLTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQN 123
Query: 332 LNLSQNEISLIGEDLHQAPRLKILRLDENCL 240
L ++ N I + +L Q +L+ L L N L
Sbjct: 124 LAITANRIETLPPELFQCRKLRALHLGNNVL 154
Score = 80.2 bits (189), Expect = 7e-15
Identities = 38/102 (37%), Positives = 63/102 (61%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
K+++IP +F C LR LDLS N L+ LP D+ L++L+ L + +N+++ LP L +
Sbjct: 84 KIEKIPTQLF-YCRKLRYLDLSHNNLTFLPADIGLLQNLQNLAITANRIETLPPELFQCR 142
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQI 423
KL L++ NN +Q+LP + L NL Q+ N+L+ P ++
Sbjct: 143 KLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVEL 184
Score = 66.9 bits (156), Expect = 7e-11
Identities = 39/123 (31%), Positives = 68/123 (55%)
Frame = -2
Query: 716 IPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEV 537
IPI + +L + L L L++NK+ +P L + L+ L+L N L LP + L+ L+
Sbjct: 65 IPIQIGNLTN-LERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQN 123
Query: 536 LNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYG 357
L I+ N ++TLP L L+ ++ NN LQ+ P ++ L +L ++L N++ +P
Sbjct: 124 LAITANRIETLPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVE 183
Query: 356 MSE 348
+ E
Sbjct: 184 LGE 186
Score = 48.4 bits (110), Expect = 3e-05
Identities = 27/83 (32%), Positives = 47/83 (56%)
Frame = -2
Query: 716 IPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEV 537
+P D+ L L+NL ++ N++ LP +L + + L+ L+L +N LQ+LP + L L
Sbjct: 111 LPADI-GLLQNLQNLAITANRIETLPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQ 169
Query: 536 LNISNNFVQTLPVCLKNLNNLKQ 468
+ + N ++ LPV L LK+
Sbjct: 170 IELRGNRLECLPVELGECPLLKR 192
>BC047306-1|AAH47306.1| 367|Homo sapiens leucine rich repeat
containing 28 protein.
Length = 367
Score = 79.4 bits (187), Expect = 1e-14
Identities = 51/174 (29%), Positives = 96/174 (55%), Gaps = 2/174 (1%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLS-KLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQT 507
L L + +N L+ LP++L+ KL +L +L L SN + +PE++ +L KL+ L++S+N ++
Sbjct: 43 LERLYMKRNSLTSLPENLAQKLPNLVELYLHSNNIVVVPEAIGSLVKLQCLDLSDNALEI 102
Query: 506 LPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVIE-L 330
+ + L L+ + +NN+LQ P ++ L+ L LD+S N++ +P + ++ L
Sbjct: 103 VCPEIGRLRALRHLRLANNQLQFLPPEVGDLKELQTLDISTNRLLTLPERLHMCLSLQYL 162
Query: 329 NLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIHTVSVDGNL 168
+ +N + + L Q P L L + N L+ + L R ++ V VD N+
Sbjct: 163 TVDRNRLWYVPRHLCQLPSLNELSMAGNRLAF--LPLDLGRSRELQYVYVDNNI 214
Score = 72.1 bits (169), Expect = 2e-12
Identities = 41/129 (31%), Positives = 72/129 (55%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTL 504
L+ LDLS N L ++ ++ +L+ L+ L L +N+LQ LP + +LK+L+ L+IS N + TL
Sbjct: 90 LQCLDLSDNALEIVCPEIGRLRALRHLRLANNQLQFLPPEVGDLKELQTLDISTNRLLTL 149
Query: 503 PVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVIELNL 324
P L +L+ + N+L P+ + L SL+ L ++ N++ +P + ++
Sbjct: 150 PERLHMCLSLQYLTVDRNRLWYVPRHLCQLPSLNELSMAGNRLAFLPLDLGRSRELQYVY 209
Query: 323 SQNEISLIG 297
N I L G
Sbjct: 210 VDNNIHLKG 218
Score = 65.7 bits (153), Expect = 2e-10
Identities = 42/161 (26%), Positives = 84/161 (52%), Gaps = 1/161 (0%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKK 546
L +P ++ L L L N + V+P+ + L L+ L+L N L+ + + L+
Sbjct: 53 LTSLPENLAQKLPNLVELYLHSNNIVVVPEAIGSLVKLQCLDLSDNALEIVCPEIGRLRA 112
Query: 545 LEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEI 366
L L ++NN +Q LP + +L L+ + S N+L P+++ SL L + N++ +
Sbjct: 113 LRHLRLANNQLQFLPPEVGDLKELQTLDISTNRLLTLPERLHMCLSLQYLTVDRNRLWYV 172
Query: 365 PYGMSELYVI-ELNLSQNEISLIGEDLHQAPRLKILRLDEN 246
P + +L + EL+++ N ++ + DL ++ L+ + +D N
Sbjct: 173 PRHLCQLPSLNELSMAGNRLAFLPLDLGRSRELQYVYVDNN 213
>BC009613-1|AAH09613.1| 335|Homo sapiens leucine rich repeat
containing 39 protein.
Length = 335
Score = 79.4 bits (187), Expect = 1e-14
Identities = 44/144 (30%), Positives = 82/144 (56%), Gaps = 2/144 (1%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNK-LSVLPDDLSKLKHLKQLNLDSNKLQALPESLINL 552
K+K +P ++ S C L L+L+ N+ + LP +LS L L L+L N +P +++N+
Sbjct: 140 KIKTVPKEL-SNCASLEKLELAVNRDICDLPQELSNLLKLTHLDLSMNDFTTIPLAVLNM 198
Query: 551 KKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKIT 372
LE L++ +N ++ LP ++ + NL ++ N++ P+ I +++L L LS+NK+
Sbjct: 199 PALEWLDMGSNKLEQLPDTIERMQNLHTLWLQRNEITCLPQTISNMKNLGTLVLSNNKLQ 258
Query: 371 EIPYGMSELYVIE-LNLSQNEISL 303
+IP M E+ + +N N + L
Sbjct: 259 DIPVCMEEMANLRFVNFRDNPLKL 282
Score = 75.4 bits (177), Expect = 2e-13
Identities = 48/170 (28%), Positives = 89/170 (52%), Gaps = 2/170 (1%)
Frame = -2
Query: 674 LDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTLPVC 495
L + K + LP L KL L++ L L +PE + + L VL++S N + +P
Sbjct: 65 LKIEKEEWKTLPSSLLKLNQLQEWQLHRTGLLKIPEFIGRFQNLIVLDLSRNTISEIPPG 124
Query: 494 LKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNK-ITEIPYGMSELY-VIELNLS 321
+ L L+++ S NK++ PK++ SL+ L+L+ N+ I ++P +S L + L+LS
Sbjct: 125 IGLLTRLQELILSYNKIKTVPKELSNCASLEKLELAVNRDICDLPQELSNLLKLTHLDLS 184
Query: 320 QNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIHTVSVDGN 171
N+ + I + P L+ L + N L+++ ++ R +HT+ + N
Sbjct: 185 MNDFTTIPLAVLNMPALEWLDMGSN--KLEQLPDTIERMQNLHTLWLQRN 232
Score = 52.4 bits (120), Expect = 2e-06
Identities = 37/99 (37%), Positives = 51/99 (51%), Gaps = 1/99 (1%)
Frame = -2
Query: 539 VLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPY 360
+L I +TLP L LN L++ L P+ I Q+L VLDLS N I+EIP
Sbjct: 64 ILKIEKEEWKTLPSSLLKLNQLQEWQLHRTGLLKIPEFIGRFQNLIVLDLSRNTISEIPP 123
Query: 359 GMSELYVI-ELNLSQNEISLIGEDLHQAPRLKILRLDEN 246
G+ L + EL LS N+I + ++L L+ L L N
Sbjct: 124 GIGLLTRLQELILSYNKIKTVPKELSNCASLEKLELAVN 162
>AY358131-1|AAQ88498.1| 335|Homo sapiens densin hlg protein.
Length = 335
Score = 79.4 bits (187), Expect = 1e-14
Identities = 44/144 (30%), Positives = 82/144 (56%), Gaps = 2/144 (1%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNK-LSVLPDDLSKLKHLKQLNLDSNKLQALPESLINL 552
K+K +P ++ S C L L+L+ N+ + LP +LS L L L+L N +P +++N+
Sbjct: 140 KIKTVPKEL-SNCASLEKLELAVNRDICDLPQELSNLLKLTHLDLSMNDFTTIPLAVLNM 198
Query: 551 KKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKIT 372
LE L++ +N ++ LP ++ + NL ++ N++ P+ I +++L L LS+NK+
Sbjct: 199 PALEWLDMGSNKLEQLPDTIERMQNLHTLWLQRNEITCLPQTISNMKNLGTLVLSNNKLQ 258
Query: 371 EIPYGMSELYVIE-LNLSQNEISL 303
+IP M E+ + +N N + L
Sbjct: 259 DIPVCMEEMANLRFVNFRDNPLKL 282
Score = 75.4 bits (177), Expect = 2e-13
Identities = 48/170 (28%), Positives = 89/170 (52%), Gaps = 2/170 (1%)
Frame = -2
Query: 674 LDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTLPVC 495
L + K + LP L KL L++ L L +PE + + L VL++S N + +P
Sbjct: 65 LKIEKEEWKTLPSSLLKLNQLQEWQLHRTGLLKIPEFIGRFQNLIVLDLSRNTISEIPPG 124
Query: 494 LKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNK-ITEIPYGMSELY-VIELNLS 321
+ L L+++ S NK++ PK++ SL+ L+L+ N+ I ++P +S L + L+LS
Sbjct: 125 IGLLTRLQELILSYNKIKTVPKELSNCASLEKLELAVNRDICDLPQELSNLLKLTHLDLS 184
Query: 320 QNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIHTVSVDGN 171
N+ + I + P L+ L + N L+++ ++ R +HT+ + N
Sbjct: 185 MNDFTTIPLAVLNMPALEWLDMGSN--KLEQLPDTIERMQNLHTLWLQRN 232
Score = 52.4 bits (120), Expect = 2e-06
Identities = 37/99 (37%), Positives = 51/99 (51%), Gaps = 1/99 (1%)
Frame = -2
Query: 539 VLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPY 360
+L I +TLP L LN L++ L P+ I Q+L VLDLS N I+EIP
Sbjct: 64 ILKIEKEEWKTLPSSLLKLNQLQEWQLHRTGLLKIPEFIGRFQNLIVLDLSRNTISEIPP 123
Query: 359 GMSELYVI-ELNLSQNEISLIGEDLHQAPRLKILRLDEN 246
G+ L + EL LS N+I + ++L L+ L L N
Sbjct: 124 GIGLLTRLQELILSYNKIKTVPKELSNCASLEKLELAVN 162
>AY358082-1|AAQ88449.1| 312|Homo sapiens ASEL436 protein.
Length = 312
Score = 79.4 bits (187), Expect = 1e-14
Identities = 51/174 (29%), Positives = 96/174 (55%), Gaps = 2/174 (1%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLS-KLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQT 507
L L + +N L+ LP++L+ KL +L +L L SN + +PE++ +L KL+ L++S+N ++
Sbjct: 43 LERLYMKRNSLTSLPENLAQKLPNLVELYLHSNNIVVVPEAIGSLVKLQCLDLSDNALEI 102
Query: 506 LPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVIE-L 330
+ + L L+ + +NN+LQ P ++ L+ L LD+S N++ +P + ++ L
Sbjct: 103 VCPEIGRLRALRHLRLANNQLQFLPPEVGDLKELQTLDISTNRLLTLPERLHMCLSLQYL 162
Query: 329 NLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIHTVSVDGNL 168
+ +N + + L Q P L L + N L+ + L R ++ V VD N+
Sbjct: 163 TVDRNRLWYVPRHLCQLPSLNELSMAGNRLAF--LPLDLGRSRELQYVYVDNNI 214
Score = 72.1 bits (169), Expect = 2e-12
Identities = 41/129 (31%), Positives = 72/129 (55%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTL 504
L+ LDLS N L ++ ++ +L+ L+ L L +N+LQ LP + +LK+L+ L+IS N + TL
Sbjct: 90 LQCLDLSDNALEIVCPEIGRLRALRHLRLANNQLQFLPPEVGDLKELQTLDISTNRLLTL 149
Query: 503 PVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVIELNL 324
P L +L+ + N+L P+ + L SL+ L ++ N++ +P + ++
Sbjct: 150 PERLHMCLSLQYLTVDRNRLWYVPRHLCQLPSLNELSMAGNRLAFLPLDLGRSRELQYVY 209
Query: 323 SQNEISLIG 297
N I L G
Sbjct: 210 VDNNIHLKG 218
Score = 65.7 bits (153), Expect = 2e-10
Identities = 42/161 (26%), Positives = 84/161 (52%), Gaps = 1/161 (0%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKK 546
L +P ++ L L L N + V+P+ + L L+ L+L N L+ + + L+
Sbjct: 53 LTSLPENLAQKLPNLVELYLHSNNIVVVPEAIGSLVKLQCLDLSDNALEIVCPEIGRLRA 112
Query: 545 LEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEI 366
L L ++NN +Q LP + +L L+ + S N+L P+++ SL L + N++ +
Sbjct: 113 LRHLRLANNQLQFLPPEVGDLKELQTLDISTNRLLTLPERLHMCLSLQYLTVDRNRLWYV 172
Query: 365 PYGMSELYVI-ELNLSQNEISLIGEDLHQAPRLKILRLDEN 246
P + +L + EL+++ N ++ + DL ++ L+ + +D N
Sbjct: 173 PRHLCQLPSLNELSMAGNRLAFLPLDLGRSRELQYVYVDNN 213
>AL445928-6|CAH72254.1| 339|Homo sapiens leucine rich repeat
containing 39 protein.
Length = 339
Score = 79.4 bits (187), Expect = 1e-14
Identities = 44/144 (30%), Positives = 82/144 (56%), Gaps = 2/144 (1%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNK-LSVLPDDLSKLKHLKQLNLDSNKLQALPESLINL 552
K+K +P ++ S C L L+L+ N+ + LP +LS L L L+L N +P +++N+
Sbjct: 140 KIKTVPKEL-SNCASLEKLELAVNRDICDLPQELSNLLKLTHLDLSMNDFTTIPLAVLNM 198
Query: 551 KKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKIT 372
LE L++ +N ++ LP ++ + NL ++ N++ P+ I +++L L LS+NK+
Sbjct: 199 PALEWLDMGSNKLEQLPDTIERMQNLHTLWLQRNEITCLPQTISNMKNLGTLVLSNNKLQ 258
Query: 371 EIPYGMSELYVIE-LNLSQNEISL 303
+IP M E+ + +N N + L
Sbjct: 259 DIPVCMEEMANLRFVNFRDNPLKL 282
Score = 75.4 bits (177), Expect = 2e-13
Identities = 48/170 (28%), Positives = 89/170 (52%), Gaps = 2/170 (1%)
Frame = -2
Query: 674 LDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTLPVC 495
L + K + LP L KL L++ L L +PE + + L VL++S N + +P
Sbjct: 65 LKIEKEEWKTLPSSLLKLNQLQEWQLHRTGLLKIPEFIGRFQNLIVLDLSRNTISEIPPG 124
Query: 494 LKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNK-ITEIPYGMSELY-VIELNLS 321
+ L L+++ S NK++ PK++ SL+ L+L+ N+ I ++P +S L + L+LS
Sbjct: 125 IGLLTRLQELILSYNKIKTVPKELSNCASLEKLELAVNRDICDLPQELSNLLKLTHLDLS 184
Query: 320 QNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIHTVSVDGN 171
N+ + I + P L+ L + N L+++ ++ R +HT+ + N
Sbjct: 185 MNDFTTIPLAVLNMPALEWLDMGSN--KLEQLPDTIERMQNLHTLWLQRN 232
Score = 52.4 bits (120), Expect = 2e-06
Identities = 37/99 (37%), Positives = 51/99 (51%), Gaps = 1/99 (1%)
Frame = -2
Query: 539 VLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPY 360
+L I +TLP L LN L++ L P+ I Q+L VLDLS N I+EIP
Sbjct: 64 ILKIEKEEWKTLPSSLLKLNQLQEWQLHRTGLLKIPEFIGRFQNLIVLDLSRNTISEIPP 123
Query: 359 GMSELYVI-ELNLSQNEISLIGEDLHQAPRLKILRLDEN 246
G+ L + EL LS N+I + ++L L+ L L N
Sbjct: 124 GIGLLTRLQELILSYNKIKTVPKELSNCASLEKLELAVN 162
>AL445928-5|CAH72253.1| 335|Homo sapiens leucine rich repeat
containing 39 protein.
Length = 335
Score = 79.4 bits (187), Expect = 1e-14
Identities = 44/144 (30%), Positives = 82/144 (56%), Gaps = 2/144 (1%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNK-LSVLPDDLSKLKHLKQLNLDSNKLQALPESLINL 552
K+K +P ++ S C L L+L+ N+ + LP +LS L L L+L N +P +++N+
Sbjct: 140 KIKTVPKEL-SNCASLEKLELAVNRDICDLPQELSNLLKLTHLDLSMNDFTTIPLAVLNM 198
Query: 551 KKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKIT 372
LE L++ +N ++ LP ++ + NL ++ N++ P+ I +++L L LS+NK+
Sbjct: 199 PALEWLDMGSNKLEQLPDTIERMQNLHTLWLQRNEITCLPQTISNMKNLGTLVLSNNKLQ 258
Query: 371 EIPYGMSELYVIE-LNLSQNEISL 303
+IP M E+ + +N N + L
Sbjct: 259 DIPVCMEEMANLRFVNFRDNPLKL 282
Score = 75.4 bits (177), Expect = 2e-13
Identities = 48/170 (28%), Positives = 89/170 (52%), Gaps = 2/170 (1%)
Frame = -2
Query: 674 LDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTLPVC 495
L + K + LP L KL L++ L L +PE + + L VL++S N + +P
Sbjct: 65 LKIEKEEWKTLPSSLLKLNQLQEWQLHRTGLLKIPEFIGRFQNLIVLDLSRNTISEIPPG 124
Query: 494 LKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNK-ITEIPYGMSELY-VIELNLS 321
+ L L+++ S NK++ PK++ SL+ L+L+ N+ I ++P +S L + L+LS
Sbjct: 125 IGLLTRLQELILSYNKIKTVPKELSNCASLEKLELAVNRDICDLPQELSNLLKLTHLDLS 184
Query: 320 QNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIHTVSVDGN 171
N+ + I + P L+ L + N L+++ ++ R +HT+ + N
Sbjct: 185 MNDFTTIPLAVLNMPALEWLDMGSN--KLEQLPDTIERMQNLHTLWLQRN 232
Score = 52.4 bits (120), Expect = 2e-06
Identities = 37/99 (37%), Positives = 51/99 (51%), Gaps = 1/99 (1%)
Frame = -2
Query: 539 VLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPY 360
+L I +TLP L LN L++ L P+ I Q+L VLDLS N I+EIP
Sbjct: 64 ILKIEKEEWKTLPSSLLKLNQLQEWQLHRTGLLKIPEFIGRFQNLIVLDLSRNTISEIPP 123
Query: 359 GMSELYVI-ELNLSQNEISLIGEDLHQAPRLKILRLDEN 246
G+ L + EL LS N+I + ++L L+ L L N
Sbjct: 124 GIGLLTRLQELILSYNKIKTVPKELSNCASLEKLELAVN 162
>AJ308569-1|CAC33442.1| 371|Homo sapiens leucine-rich
repeat-containing 2 protein protein.
Length = 371
Score = 79.4 bits (187), Expect = 1e-14
Identities = 51/162 (31%), Positives = 91/162 (56%), Gaps = 2/162 (1%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESL 561
I++ ++ IP + L +R LDL KN++S LP ++ LK+LK+LN+ N L+++P L
Sbjct: 128 ISNTLIQIIPTYI-QLFQEMRILDLPKNQISHLPAEIGCLKNLKELNVGFNYLKSIPPEL 186
Query: 560 INLKKLEVLNISNNF-VQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSH 384
+ + LE L+ S N + LP L NL + V S NK + P +L + +L LD+S
Sbjct: 187 GDCENLERLDCSGNLELMELPFELSNLKQVTFVDISANKFSSVPICVLRMSNLQWLDISS 246
Query: 383 NKITEIPYGMSELYVIE-LNLSQNEISLIGEDLHQAPRLKIL 261
N +T++P + L ++ L +N+++ + + +L +L
Sbjct: 247 NNLTDLPQDIDRLEELQSFLLYKNKLTYLPYSMLNLKKLTLL 288
Score = 68.1 bits (159), Expect = 3e-11
Identities = 42/173 (24%), Positives = 93/173 (53%), Gaps = 2/173 (1%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTL 504
LR +S + ++P + + ++ L+L N++ LP + LK L+ LN+ N+++++
Sbjct: 123 LREWYISNTLIQIIPTYIQLFQEMRILDLPKNQISHLPAEIGCLKNLKELNVGFNYLKSI 182
Query: 503 PVCLKNLNNLKQVYASNN-KLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVIE-L 330
P L + NL+++ S N +L P ++ L+ + +D+S NK + +P + + ++ L
Sbjct: 183 PPELGDCENLERLDCSGNLELMELPFELSNLKQVTFVDISANKFSSVPICVLRMSNLQWL 242
Query: 329 NLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIHTVSVDGN 171
++S N ++ + +D+ + L+ L +N L + S+L K+ + V G+
Sbjct: 243 DISSNNLTDLPQDIDRLEELQSFLLYKN--KLTYLPYSMLNLKKLTLLVVSGD 293
Score = 67.7 bits (158), Expect = 4e-11
Identities = 40/127 (31%), Positives = 70/127 (55%), Gaps = 1/127 (0%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKN-KLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
LK IP ++ C+ L LD S N +L LP +LS LK + +++ +NK ++P ++ +
Sbjct: 179 LKSIPPELGD-CENLERLDCSGNLELMELPFELSNLKQVTFVDISANKFSSVPICVLRMS 237
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITE 369
L+ L+IS+N + LP + L L+ NKL P +L L+ L +L +S + + E
Sbjct: 238 NLQWLDISSNNLTDLPQDIDRLEELQSFLLYKNKLTYLPYSMLNLKKLTLLVVSGDHLVE 297
Query: 368 IPYGMSE 348
+P + +
Sbjct: 298 LPTALCD 304
Score = 62.5 bits (145), Expect = 2e-09
Identities = 38/147 (25%), Positives = 80/147 (54%), Gaps = 2/147 (1%)
Frame = -2
Query: 671 DLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTLPVCL 492
+LS + LPD L + HL++ + + +Q +P + +++ +L++ N + LP +
Sbjct: 104 ELSGEHWTELPDSLKEQTHLREWYISNTLIQIIPTYIQLFQEMRILDLPKNQISHLPAEI 163
Query: 491 KNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHN-KITEIPYGMSEL-YVIELNLSQ 318
L NLK++ N L++ P ++ ++L+ LD S N ++ E+P+ +S L V +++S
Sbjct: 164 GCLKNLKELNVGFNYLKSIPPELGDCENLERLDCSGNLELMELPFELSNLKQVTFVDISA 223
Query: 317 NEISLIGEDLHQAPRLKILRLDENCLS 237
N+ S + + + L+ L + N L+
Sbjct: 224 NKFSSVPICVLRMSNLQWLDISSNNLT 250
Score = 47.6 bits (108), Expect = 5e-05
Identities = 49/200 (24%), Positives = 88/200 (44%), Gaps = 10/200 (5%)
Frame = -2
Query: 740 IADCKLKEIPIDVF---SLCDV-LRNLD-LSKNKL---SVLPDDLSKLKHLKQLNLDSNK 585
+A+C+ K IP V+ D +R LD + +N L S LP D K L
Sbjct: 50 VAECRRKGIPQAVYCKNGFIDTSVRLLDKIERNTLTRQSSLPKDRGKRSSAFVFELSGEH 109
Query: 584 LQALPESLINLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSL 405
LP+SL L ISN +Q +P ++ ++ + N++ P +I L++L
Sbjct: 110 WTELPDSLKEQTHLREWYISNTLIQIIPTYIQLFQEMRILDLPKNQISHLPAEIGCLKNL 169
Query: 404 DVLDLSHNKITEIPYGMSELYVIE-LNLSQN-EISLIGEDLHQAPRLKILRLDENCLSLD 231
L++ N + IP + + +E L+ S N E+ + +L ++ + + N S
Sbjct: 170 KELNVGFNYLKSIPPELGDCENLERLDCSGNLELMELPFELSNLKQVTFVDISANKFS-- 227
Query: 230 EIKPSLLRDSKIHTVSVDGN 171
+ +LR S + + + N
Sbjct: 228 SVPICVLRMSNLQWLDISSN 247
>AF229178-1|AAF69491.1| 753|Homo sapiens leucine rich repeat and
death domain containing protein protein.
Length = 753
Score = 79.0 bits (186), Expect = 2e-14
Identities = 46/136 (33%), Positives = 79/136 (58%), Gaps = 1/136 (0%)
Frame = -2
Query: 668 LSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTLPVCLK 489
LS N LS LP+ L L L L + N+LQ LP +L L L+ L++S N + TLP +
Sbjct: 9 LSHNCLSELPEALGALPALTFLTVTHNRLQTLPPALGALSTLQRLDLSQNLLDTLPPEIG 68
Query: 488 NLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVI-ELNLSQNE 312
L +L ++ ++N+LQ+ P + GL+SL +L L N + +P ++ L ++ L+L N+
Sbjct: 69 GLGSLLELNLASNRLQSLPASLAGLRSLRLLVLHSNLLASVPADLARLPLLTRLDLRDNQ 128
Query: 311 ISLIGEDLHQAPRLKI 264
+ + +L AP +++
Sbjct: 129 LRDLPPELLDAPFVRL 144
Score = 68.1 bits (159), Expect = 3e-11
Identities = 48/139 (34%), Positives = 75/139 (53%), Gaps = 1/139 (0%)
Frame = -2
Query: 623 LKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKL 444
++ L L L N L LPE+L L L L +++N +QTLP L L+ L+++ S N L
Sbjct: 1 MRGLGALLLSHNCLSELPEALGALPALTFLTVTHNRLQTLPPALGALSTLQRLDLSQNLL 60
Query: 443 QAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVIE-LNLSQNEISLIGEDLHQAPRLK 267
P +I GL SL L+L+ N++ +P ++ L + L L N ++ + DL + P L
Sbjct: 61 DTLPPEIGGLGSLLELNLASNRLQSLPASLAGLRSLRLLVLHSNLLASVPADLARLPLLT 120
Query: 266 ILRLDENCLSLDEIKPSLL 210
L L +N L ++ P LL
Sbjct: 121 RLDLRDN--QLRDLPPELL 137
Score = 66.9 bits (156), Expect = 7e-11
Identities = 39/121 (32%), Positives = 63/121 (52%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKK 546
L E+P + L L ++ N+L LP L L L++L+L N L LP + L
Sbjct: 14 LSELP-EALGALPALTFLTVTHNRLQTLPPALGALSTLQRLDLSQNLLDTLPPEIGGLGS 72
Query: 545 LEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEI 366
L LN+++N +Q+LP L L +L+ + +N L + P + L L LDL N++ ++
Sbjct: 73 LLELNLASNRLQSLPASLAGLRSLRLLVLHSNLLASVPADLARLPLLTRLDLRDNQLRDL 132
Query: 365 P 363
P
Sbjct: 133 P 133
Score = 66.5 bits (155), Expect = 9e-11
Identities = 37/103 (35%), Positives = 63/103 (61%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
+L+ +P + +L L+ LDLS+N L LP ++ L L +LNL SN+LQ+LP SL L+
Sbjct: 36 RLQTLPPALGAL-STLQRLDLSQNLLDTLPPEIGGLGSLLELNLASNRLQSLPASLAGLR 94
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQIL 420
L +L + +N + ++P L L L ++ +N+L+ P ++L
Sbjct: 95 SLRLLVLHSNLLASVPADLARLPLLTRLDLRDNQLRDLPPELL 137
>BC036722-1|AAH36722.1| 261|Homo sapiens leucine rich repeat
containing 18 protein.
Length = 261
Score = 78.6 bits (185), Expect = 2e-14
Identities = 50/143 (34%), Positives = 79/143 (55%), Gaps = 3/143 (2%)
Frame = -2
Query: 713 PIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVL 534
P + L D + LDLS+N + +PD +SK ++L+ L+L SN + LPES+ + L L
Sbjct: 43 PKCILRLSD-MDELDLSRNLIRKIPDSISKFQNLRWLDLHSNYIDKLPESIGQMTSLLYL 101
Query: 533 NISNNFVQT--LPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPY 360
N+SNN + + LPV LK L N++ V N L + + L+ L + L N + IP
Sbjct: 102 NVSNNRLTSNGLPVELKQLKNIRAVNLGLNHLDSVSTTLGALKELHEVGLHDNLLNNIPV 161
Query: 359 GMSELYVI-ELNLSQNEISLIGE 294
+S+L + +LN+ +N GE
Sbjct: 162 SISKLPKLKKLNIKRNPFPKPGE 184
Score = 66.1 bits (154), Expect = 1e-10
Identities = 37/151 (24%), Positives = 79/151 (52%), Gaps = 3/151 (1%)
Frame = -2
Query: 689 DVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQ 510
D + LDLSK ++ P + +L + +L+L N ++ +P+S+ + L L++ +N++
Sbjct: 27 DGKKRLDLSKMGITTFPKCILRLSDMDELDLSRNLIRKIPDSISKFQNLRWLDLHSNYID 86
Query: 509 TLPVCLKNLNNLKQVYASNNKL--QAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVI 336
LP + + +L + SNN+L P ++ L+++ ++L N + + + L +
Sbjct: 87 KLPESIGQMTSLLYLNVSNNRLTSNGLPVELKQLKNIRAVNLGLNHLDSVSTTLGALKEL 146
Query: 335 -ELNLSQNEISLIGEDLHQAPRLKILRLDEN 246
E+ L N ++ I + + P+LK L + N
Sbjct: 147 HEVGLHDNLLNNIPVSISKLPKLKKLNIKRN 177
Score = 32.3 bits (70), Expect = 1.9
Identities = 28/97 (28%), Positives = 44/97 (45%), Gaps = 10/97 (10%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLI---NLKKLEVLNISNNFV 513
L + L N L+ +P +SKL LK+LN+ N ES I ++++LE L +
Sbjct: 146 LHEVGLHDNLLNNIPVSISKLPKLKKLNIKRNPFPKPGESEIFIDSIRRLENLYVVEE-K 204
Query: 512 QTLPVCLK-------NLNNLKQVYASNNKLQAFPKQI 423
CL+ NLN +K + + + FP I
Sbjct: 205 DLCAACLRKCQNARDNLNRIKNMATTTPRKTIFPNLI 241
>AK000338-1|BAA91094.1| 384|Homo sapiens protein ( Homo sapiens
cDNA FLJ20331 fis, clone HEP10410. ).
Length = 384
Score = 78.6 bits (185), Expect = 2e-14
Identities = 46/143 (32%), Positives = 85/143 (59%), Gaps = 1/143 (0%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTL 504
L++LD + N L +P +L+ ++ L+ L L NKL+ LPE + L+ L++ N ++ L
Sbjct: 4 LKHLDCNSNLLETIPPELAGMESLELLYLRRNKLRFLPE-FPSCSLLKELHVGENQIEML 62
Query: 503 PV-CLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVIELN 327
LK+LN++ + +NKL++ P +I+ L+SL+ LDLS+N I+ +PY + L++ L
Sbjct: 63 EAEHLKHLNSILVLDLRDNKLKSVPDEIILLRSLERLDLSNNDISSLPYSLGNLHLKFLA 122
Query: 326 LSQNEISLIGEDLHQAPRLKILR 258
L N + I ++ ++L+
Sbjct: 123 LEGNPLRTIRREIISKGTQEVLK 145
Score = 73.7 bits (173), Expect = 6e-13
Identities = 42/123 (34%), Positives = 77/123 (62%), Gaps = 1/123 (0%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
+L EIP + L +++ ++DLS NKLS + +L L+ L L+L +N L +LPE + +L
Sbjct: 218 QLCEIPKRMVELKEMVSDVDLSFNKLSFISLELCVLQKLTFLDLRNNFLNSLPEEMESLV 277
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAF-PKQILGLQSLDVLDLSHNKIT 372
+L+ +N+S N + LP L + L+ + SNN++ + P+++ +++L LDL +N +
Sbjct: 278 RLQTINLSFNRFKMLPEVLYRIFTLETILISNNQVGSVDPQKMKMMENLTTLDLQNNDLL 337
Query: 371 EIP 363
+IP
Sbjct: 338 QIP 340
Score = 45.2 bits (102), Expect = 2e-04
Identities = 36/143 (25%), Positives = 68/143 (47%), Gaps = 6/143 (4%)
Frame = -2
Query: 614 LKQLNLDSNKLQALPESLINLKKLEV---LNISNNFVQTLPVCLKNLNNL-KQVYASNNK 447
LK L+ + +P+ + + K + +N S N + +P + L + V S NK
Sbjct: 183 LKILDYSDKQATLIPDEVFDAVKSNIVTSINFSKNQLCEIPKRMVELKEMVSDVDLSFNK 242
Query: 446 LQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVIE-LNLSQNEISLIGEDLHQAPRL 270
L ++ LQ L LDL +N + +P M L ++ +NLS N ++ E L++ L
Sbjct: 243 LSFISLELCVLQKLTFLDLRNNFLNSLPEEMESLVRLQTINLSFNRFKMLPEVLYRIFTL 302
Query: 269 KILRLDENCL-SLDEIKPSLLRD 204
+ + + N + S+D K ++ +
Sbjct: 303 ETILISNNQVGSVDPQKMKMMEN 325
Score = 43.6 bits (98), Expect = 8e-04
Identities = 24/83 (28%), Positives = 47/83 (56%), Gaps = 1/83 (1%)
Frame = -2
Query: 485 LNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVIELNLSQNEIS 306
+ LK + ++N L+ P ++ G++SL++L L NK+ +P S + EL++ +N+I
Sbjct: 1 MKRLKHLDCNSNLLETIPPELAGMESLELLYLRRNKLRFLPEFPSCSLLKELHVGENQIE 60
Query: 305 LI-GEDLHQAPRLKILRLDENCL 240
++ E L + +L L +N L
Sbjct: 61 MLEAEHLKHLNSILVLDLRDNKL 83
Score = 41.5 bits (93), Expect = 0.003
Identities = 28/118 (23%), Positives = 63/118 (53%), Gaps = 1/118 (0%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQAL-PESLINLK 549
L +P ++ SL L+ ++LS N+ +LP+ L ++ L+ + + +N++ ++ P+ + ++
Sbjct: 266 LNSLPEEMESLVR-LQTINLSFNRFKMLPEVLYRIFTLETILISNNQVGSVDPQKMKMME 324
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKI 375
L L++ NN + +P L N NL+ + N + IL + +L+ ++I
Sbjct: 325 NLTTLDLQNNDLLQIPPELGNCVNLRTLLLDGNPFRVPRAAILMKGTAAILEYLRDRI 382
Score = 37.5 bits (83), Expect = 0.050
Identities = 37/129 (28%), Positives = 62/129 (48%), Gaps = 24/129 (18%)
Frame = -2
Query: 554 LKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFP------------------- 432
+K+L+ L+ ++N ++T+P L + +L+ +Y NKL+ P
Sbjct: 1 MKRLKHLDCNSNLLETIPPELAGMESLELLYLRRNKLRFLPEFPSCSLLKELHVGENQIE 60
Query: 431 ----KQILGLQSLDVLDLSHNKITEIPYGMSELYVIE-LNLSQNEISLIGEDLHQAPRLK 267
+ + L S+ VLDL NK+ +P + L +E L+LS N+IS + L LK
Sbjct: 61 MLEAEHLKHLNSILVLDLRDNKLKSVPDEIILLRSLERLDLSNNDISSLPYSLGNL-HLK 119
Query: 266 ILRLDENCL 240
L L+ N L
Sbjct: 120 FLALEGNPL 128
>BC108252-1|AAI08253.1| 532|Homo sapiens LRRC8E protein protein.
Length = 532
Score = 77.0 bits (181), Expect = 7e-14
Identities = 56/188 (29%), Positives = 99/188 (52%), Gaps = 5/188 (2%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPE--SLINLKKLEVLNISNNFVQ 510
LR L+L L +P + L L++L+L N L+++ E S + +KL L + +N +
Sbjct: 320 LRELELVACGLERIPHAVFSLGALQELDLKDNHLRSIEEILSFQHCRKLVTLRLWHNQIA 379
Query: 509 TLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVIE- 333
+P ++ L +L+Q+Y S NKL+ P Q+ L +LD+SHN + +P + L ++
Sbjct: 380 YVPEHVRKLRSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHNGLHSLPPEVGLLQNLQH 439
Query: 332 LNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIHTVSVDGNLFE--P 159
L LS N + + E+L +L+ L L +N LS ++ P + + + + GN E P
Sbjct: 440 LALSYNALEALPEELFFCRKLRTLLLGDNQLS--QLSPHVGALRALSRLELKGNRLEALP 497
Query: 158 KQLAXLEG 135
++L G
Sbjct: 498 EELGNCGG 505
Score = 72.9 bits (171), Expect = 1e-12
Identities = 45/146 (30%), Positives = 78/146 (53%), Gaps = 1/146 (0%)
Frame = -2
Query: 701 FSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISN 522
F C L L L N+++ +P+ + KL+ L+QL L NKL+ LP L L +L++S+
Sbjct: 362 FQHCRKLVTLRLWHNQIAYVPEHVRKLRSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSH 421
Query: 521 NFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELY 342
N + +LP + L NL+ + S N L+A P+++ + L L L N+++++ + L
Sbjct: 422 NGLHSLPPEVGLLQNLQHLALSYNALEALPEELFFCRKLRTLLLGDNQLSQLSPHVGALR 481
Query: 341 VI-ELNLSQNEISLIGEDLHQAPRLK 267
+ L L N + + E+L LK
Sbjct: 482 ALSRLELKGNRLEALPEELGNCGGLK 507
Score = 30.7 bits (66), Expect = 5.7
Identities = 30/128 (23%), Positives = 58/128 (45%), Gaps = 7/128 (5%)
Frame = -2
Query: 608 QLNLDSNKLQALPESLINLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQ-AFP 432
+L L L LP+++ L ++E L + T P L L +L+++ ++ + F
Sbjct: 154 RLELALCMLPGLPDTVFELSEVESLRLEAICDITFPPGLSQLVHLQELSLLHSPARLPFS 213
Query: 431 KQILGLQSLDVLDLSHNKITEIPY------GMSELYVIELNLSQNEISLIGEDLHQAPRL 270
Q+ L V+ + ++ E+P G+ EL++ L + + E L + +L
Sbjct: 214 LQVFLRDHLKVMRVKCEELREVPLWVFGLRGLEELHLEGLFPQELARAATLESLRELKQL 273
Query: 269 KILRLDEN 246
K+L L N
Sbjct: 274 KVLSLRSN 281
Score = 30.3 bits (65), Expect = 7.6
Identities = 46/166 (27%), Positives = 83/166 (50%), Gaps = 11/166 (6%)
Frame = -2
Query: 710 IDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALP-----ESLINLKK 546
+ VF L D L+ + + +L +P + L+ L++L+L+ Q L ESL LK+
Sbjct: 214 LQVF-LRDHLKVMRVKCEELREVPLWVFGLRGLEELHLEGLFPQELARAATLESLRELKQ 272
Query: 545 LEVLNISNNFVQTLPVCLKNL-NNLKQVYASNN--KLQAFPKQILGLQSLDVLDLSHNKI 375
L+VL++ +N +P + ++ +L+++ N+ +L A + L +L L+L +
Sbjct: 273 LKVLSLRSN-AGKVPASVTDVAGHLQRLSLHNDGARLVAL-NSLKKLAALRELELVACGL 330
Query: 374 TEIPYGMSELYVI-ELNLSQNEISLIGEDL--HQAPRLKILRLDEN 246
IP+ + L + EL+L N + I E L +L LRL N
Sbjct: 331 ERIPHAVFSLGALQELDLKDNHLRSIEEILSFQHCRKLVTLRLWHN 376
>BC070089-1|AAH70089.1| 796|Homo sapiens leucine rich repeat
containing 8 family, member E protein.
Length = 796
Score = 77.0 bits (181), Expect = 7e-14
Identities = 56/188 (29%), Positives = 99/188 (52%), Gaps = 5/188 (2%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPE--SLINLKKLEVLNISNNFVQ 510
LR L+L L +P + L L++L+L N L+++ E S + +KL L + +N +
Sbjct: 584 LRELELVACGLERIPHAVFSLGALQELDLKDNHLRSIEEILSFQHCRKLVTLRLWHNQIA 643
Query: 509 TLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVIE- 333
+P ++ L +L+Q+Y S NKL+ P Q+ L +LD+SHN + +P + L ++
Sbjct: 644 YVPEHVRKLRSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHNGLHSLPPEVGLLQNLQH 703
Query: 332 LNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIHTVSVDGNLFE--P 159
L LS N + + E+L +L+ L L +N LS ++ P + + + + GN E P
Sbjct: 704 LALSYNALEALPEELFFCRKLRTLLLGDNQLS--QLSPHVGALRALSRLELKGNRLEALP 761
Query: 158 KQLAXLEG 135
++L G
Sbjct: 762 EELGNCGG 769
Score = 72.9 bits (171), Expect = 1e-12
Identities = 45/146 (30%), Positives = 78/146 (53%), Gaps = 1/146 (0%)
Frame = -2
Query: 701 FSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISN 522
F C L L L N+++ +P+ + KL+ L+QL L NKL+ LP L L +L++S+
Sbjct: 626 FQHCRKLVTLRLWHNQIAYVPEHVRKLRSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSH 685
Query: 521 NFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELY 342
N + +LP + L NL+ + S N L+A P+++ + L L L N+++++ + L
Sbjct: 686 NGLHSLPPEVGLLQNLQHLALSYNALEALPEELFFCRKLRTLLLGDNQLSQLSPHVGALR 745
Query: 341 VI-ELNLSQNEISLIGEDLHQAPRLK 267
+ L L N + + E+L LK
Sbjct: 746 ALSRLELKGNRLEALPEELGNCGGLK 771
Score = 30.7 bits (66), Expect = 5.7
Identities = 30/128 (23%), Positives = 58/128 (45%), Gaps = 7/128 (5%)
Frame = -2
Query: 608 QLNLDSNKLQALPESLINLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQ-AFP 432
+L L L LP+++ L ++E L + T P L L +L+++ ++ + F
Sbjct: 418 RLELALCMLPGLPDTVFELSEVESLRLEAICDITFPPGLSQLVHLQELSLLHSPARLPFS 477
Query: 431 KQILGLQSLDVLDLSHNKITEIPY------GMSELYVIELNLSQNEISLIGEDLHQAPRL 270
Q+ L V+ + ++ E+P G+ EL++ L + + E L + +L
Sbjct: 478 LQVFLRDHLKVMRVKCEELREVPLWVFGLRGLEELHLEGLFPQELARAATLESLRELKQL 537
Query: 269 KILRLDEN 246
K+L L N
Sbjct: 538 KVLSLRSN 545
Score = 30.3 bits (65), Expect = 7.6
Identities = 46/166 (27%), Positives = 83/166 (50%), Gaps = 11/166 (6%)
Frame = -2
Query: 710 IDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALP-----ESLINLKK 546
+ VF L D L+ + + +L +P + L+ L++L+L+ Q L ESL LK+
Sbjct: 478 LQVF-LRDHLKVMRVKCEELREVPLWVFGLRGLEELHLEGLFPQELARAATLESLRELKQ 536
Query: 545 LEVLNISNNFVQTLPVCLKNL-NNLKQVYASNN--KLQAFPKQILGLQSLDVLDLSHNKI 375
L+VL++ +N +P + ++ +L+++ N+ +L A + L +L L+L +
Sbjct: 537 LKVLSLRSN-AGKVPASVTDVAGHLQRLSLHNDGARLVAL-NSLKKLAALRELELVACGL 594
Query: 374 TEIPYGMSELYVI-ELNLSQNEISLIGEDL--HQAPRLKILRLDEN 246
IP+ + L + EL+L N + I E L +L LRL N
Sbjct: 595 ERIPHAVFSLGALQELDLKDNHLRSIEEILSFQHCRKLVTLRLWHN 640
>BC022216-1|AAH22216.2| 592|Homo sapiens LRRC8E protein protein.
Length = 592
Score = 77.0 bits (181), Expect = 7e-14
Identities = 56/188 (29%), Positives = 99/188 (52%), Gaps = 5/188 (2%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPE--SLINLKKLEVLNISNNFVQ 510
LR L+L L +P + L L++L+L N L+++ E S + +KL L + +N +
Sbjct: 380 LRELELVACGLERIPHAVFSLGALQELDLKDNHLRSIEEILSFQHCRKLVTLRLWHNQIA 439
Query: 509 TLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVIE- 333
+P ++ L +L+Q+Y S NKL+ P Q+ L +LD+SHN + +P + L ++
Sbjct: 440 YVPEHVRKLRSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHNGLHSLPPEVGLLQNLQH 499
Query: 332 LNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIHTVSVDGNLFE--P 159
L LS N + + E+L +L+ L L +N LS ++ P + + + + GN E P
Sbjct: 500 LALSYNALEALPEELFFCRKLRTLLLGDNQLS--QLSPHVGALRALSRLELKGNRLEALP 557
Query: 158 KQLAXLEG 135
++L G
Sbjct: 558 EELGNCGG 565
Score = 72.9 bits (171), Expect = 1e-12
Identities = 45/146 (30%), Positives = 78/146 (53%), Gaps = 1/146 (0%)
Frame = -2
Query: 701 FSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISN 522
F C L L L N+++ +P+ + KL+ L+QL L NKL+ LP L L +L++S+
Sbjct: 422 FQHCRKLVTLRLWHNQIAYVPEHVRKLRSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSH 481
Query: 521 NFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELY 342
N + +LP + L NL+ + S N L+A P+++ + L L L N+++++ + L
Sbjct: 482 NGLHSLPPEVGLLQNLQHLALSYNALEALPEELFFCRKLRTLLLGDNQLSQLSPHVGALR 541
Query: 341 VI-ELNLSQNEISLIGEDLHQAPRLK 267
+ L L N + + E+L LK
Sbjct: 542 ALSRLELKGNRLEALPEELGNCGGLK 567
Score = 30.7 bits (66), Expect = 5.7
Identities = 30/128 (23%), Positives = 58/128 (45%), Gaps = 7/128 (5%)
Frame = -2
Query: 608 QLNLDSNKLQALPESLINLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQ-AFP 432
+L L L LP+++ L ++E L + T P L L +L+++ ++ + F
Sbjct: 214 RLELALCMLPGLPDTVFELSEVESLRLEAICDITFPPGLSQLVHLQELSLLHSPARLPFS 273
Query: 431 KQILGLQSLDVLDLSHNKITEIPY------GMSELYVIELNLSQNEISLIGEDLHQAPRL 270
Q+ L V+ + ++ E+P G+ EL++ L + + E L + +L
Sbjct: 274 LQVFLRDHLKVMRVKCEELREVPLWVFGLRGLEELHLEGLFPQELARAATLESLRELKQL 333
Query: 269 KILRLDEN 246
K+L L N
Sbjct: 334 KVLSLRSN 341
Score = 30.3 bits (65), Expect = 7.6
Identities = 46/166 (27%), Positives = 83/166 (50%), Gaps = 11/166 (6%)
Frame = -2
Query: 710 IDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALP-----ESLINLKK 546
+ VF L D L+ + + +L +P + L+ L++L+L+ Q L ESL LK+
Sbjct: 274 LQVF-LRDHLKVMRVKCEELREVPLWVFGLRGLEELHLEGLFPQELARAATLESLRELKQ 332
Query: 545 LEVLNISNNFVQTLPVCLKNL-NNLKQVYASNN--KLQAFPKQILGLQSLDVLDLSHNKI 375
L+VL++ +N +P + ++ +L+++ N+ +L A + L +L L+L +
Sbjct: 333 LKVLSLRSN-AGKVPASVTDVAGHLQRLSLHNDGARLVAL-NSLKKLAALRELELVACGL 390
Query: 374 TEIPYGMSELYVI-ELNLSQNEISLIGEDL--HQAPRLKILRLDEN 246
IP+ + L + EL+L N + I E L +L LRL N
Sbjct: 391 ERIPHAVFSLGALQELDLKDNHLRSIEEILSFQHCRKLVTLRLWHN 436
>AL834474-1|CAD39133.1| 622|Homo sapiens hypothetical protein
protein.
Length = 622
Score = 77.0 bits (181), Expect = 7e-14
Identities = 56/188 (29%), Positives = 99/188 (52%), Gaps = 5/188 (2%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPE--SLINLKKLEVLNISNNFVQ 510
LR L+L L +P + L L++L+L N L+++ E S + +KL L + +N +
Sbjct: 410 LRELELVACGLERIPHAVFSLGALQELDLKDNHLRSIEEILSFQHCRKLVTLRLWHNQIA 469
Query: 509 TLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVIE- 333
+P ++ L +L+Q+Y S NKL+ P Q+ L +LD+SHN + +P + L ++
Sbjct: 470 YVPEHVRKLRSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHNGLHSLPPEVGLLQNLQH 529
Query: 332 LNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIHTVSVDGNLFE--P 159
L LS N + + E+L +L+ L L +N LS ++ P + + + + GN E P
Sbjct: 530 LALSYNALEALPEELFFCRKLRTLLLGDNQLS--QLSPHVGALRALSRLELKGNRLEALP 587
Query: 158 KQLAXLEG 135
++L G
Sbjct: 588 EELGNCGG 595
Score = 72.9 bits (171), Expect = 1e-12
Identities = 45/146 (30%), Positives = 78/146 (53%), Gaps = 1/146 (0%)
Frame = -2
Query: 701 FSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISN 522
F C L L L N+++ +P+ + KL+ L+QL L NKL+ LP L L +L++S+
Sbjct: 452 FQHCRKLVTLRLWHNQIAYVPEHVRKLRSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSH 511
Query: 521 NFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELY 342
N + +LP + L NL+ + S N L+A P+++ + L L L N+++++ + L
Sbjct: 512 NGLHSLPPEVGLLQNLQHLALSYNALEALPEELFFCRKLRTLLLGDNQLSQLSPHVGALR 571
Query: 341 VI-ELNLSQNEISLIGEDLHQAPRLK 267
+ L L N + + E+L LK
Sbjct: 572 ALSRLELKGNRLEALPEELGNCGGLK 597
Score = 30.7 bits (66), Expect = 5.7
Identities = 30/128 (23%), Positives = 58/128 (45%), Gaps = 7/128 (5%)
Frame = -2
Query: 608 QLNLDSNKLQALPESLINLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQ-AFP 432
+L L L LP+++ L ++E L + T P L L +L+++ ++ + F
Sbjct: 244 RLELALCMLPGLPDTVFELSEVESLRLEAICDITFPPGLSQLVHLQELSLLHSPARLPFS 303
Query: 431 KQILGLQSLDVLDLSHNKITEIPY------GMSELYVIELNLSQNEISLIGEDLHQAPRL 270
Q+ L V+ + ++ E+P G+ EL++ L + + E L + +L
Sbjct: 304 LQVFLRDHLKVMRVKCEELREVPLWVFGLRGLEELHLEGLFPQELARAATLESLRELKQL 363
Query: 269 KILRLDEN 246
K+L L N
Sbjct: 364 KVLSLRSN 371
Score = 30.3 bits (65), Expect = 7.6
Identities = 46/166 (27%), Positives = 83/166 (50%), Gaps = 11/166 (6%)
Frame = -2
Query: 710 IDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALP-----ESLINLKK 546
+ VF L D L+ + + +L +P + L+ L++L+L+ Q L ESL LK+
Sbjct: 304 LQVF-LRDHLKVMRVKCEELREVPLWVFGLRGLEELHLEGLFPQELARAATLESLRELKQ 362
Query: 545 LEVLNISNNFVQTLPVCLKNL-NNLKQVYASNN--KLQAFPKQILGLQSLDVLDLSHNKI 375
L+VL++ +N +P + ++ +L+++ N+ +L A + L +L L+L +
Sbjct: 363 LKVLSLRSN-AGKVPASVTDVAGHLQRLSLHNDGARLVAL-NSLKKLAALRELELVACGL 420
Query: 374 TEIPYGMSELYVI-ELNLSQNEISLIGEDL--HQAPRLKILRLDEN 246
IP+ + L + EL+L N + I E L +L LRL N
Sbjct: 421 ERIPHAVFSLGALQELDLKDNHLRSIEEILSFQHCRKLVTLRLWHN 466
>AK027073-1|BAB15648.1| 444|Homo sapiens protein ( Homo sapiens
cDNA: FLJ23420 fis, clone HEP22352. ).
Length = 444
Score = 77.0 bits (181), Expect = 7e-14
Identities = 56/188 (29%), Positives = 99/188 (52%), Gaps = 5/188 (2%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPE--SLINLKKLEVLNISNNFVQ 510
LR L+L L +P + L L++L+L N L+++ E S + +KL L + +N +
Sbjct: 232 LRELELVACGLERIPHAVFSLGALQELDLKDNHLRSIEEILSFQHCRKLVTLRLWHNQIA 291
Query: 509 TLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVIE- 333
+P ++ L +L+Q+Y S NKL+ P Q+ L +LD+SHN + +P + L ++
Sbjct: 292 YVPEHVRKLRSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHNGLHSLPPEVGLLQNLQH 351
Query: 332 LNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIHTVSVDGNLFE--P 159
L LS N + + E+L +L+ L L +N LS ++ P + + + + GN E P
Sbjct: 352 LALSYNALEALPEELFFCRKLRTLLLGDNQLS--QLSPHVGALRALSRLELKGNRLEALP 409
Query: 158 KQLAXLEG 135
++L G
Sbjct: 410 EELGNCGG 417
Score = 72.9 bits (171), Expect = 1e-12
Identities = 45/146 (30%), Positives = 78/146 (53%), Gaps = 1/146 (0%)
Frame = -2
Query: 701 FSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISN 522
F C L L L N+++ +P+ + KL+ L+QL L NKL+ LP L L +L++S+
Sbjct: 274 FQHCRKLVTLRLWHNQIAYVPEHVRKLRSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSH 333
Query: 521 NFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELY 342
N + +LP + L NL+ + S N L+A P+++ + L L L N+++++ + L
Sbjct: 334 NGLHSLPPEVGLLQNLQHLALSYNALEALPEELFFCRKLRTLLLGDNQLSQLSPHVGALR 393
Query: 341 VI-ELNLSQNEISLIGEDLHQAPRLK 267
+ L L N + + E+L LK
Sbjct: 394 ALSRLELKGNRLEALPEELGNCGGLK 419
Score = 30.7 bits (66), Expect = 5.7
Identities = 30/128 (23%), Positives = 58/128 (45%), Gaps = 7/128 (5%)
Frame = -2
Query: 608 QLNLDSNKLQALPESLINLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQ-AFP 432
+L L L LP+++ L ++E L + T P L L +L+++ ++ + F
Sbjct: 66 RLELALCMLPGLPDTVFELSEVESLRLEAICDITFPPGLSQLVHLQELSLLHSPARLPFS 125
Query: 431 KQILGLQSLDVLDLSHNKITEIPY------GMSELYVIELNLSQNEISLIGEDLHQAPRL 270
Q+ L V+ + ++ E+P G+ EL++ L + + E L + +L
Sbjct: 126 LQVFLRDHLKVMRVKCEELREVPLWVFGLRGLEELHLEGLFPQELARAATLESLRELKQL 185
Query: 269 KILRLDEN 246
K+L L N
Sbjct: 186 KVLSLRSN 193
Score = 30.3 bits (65), Expect = 7.6
Identities = 46/166 (27%), Positives = 83/166 (50%), Gaps = 11/166 (6%)
Frame = -2
Query: 710 IDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALP-----ESLINLKK 546
+ VF L D L+ + + +L +P + L+ L++L+L+ Q L ESL LK+
Sbjct: 126 LQVF-LRDHLKVMRVKCEELREVPLWVFGLRGLEELHLEGLFPQELARAATLESLRELKQ 184
Query: 545 LEVLNISNNFVQTLPVCLKNL-NNLKQVYASNN--KLQAFPKQILGLQSLDVLDLSHNKI 375
L+VL++ +N +P + ++ +L+++ N+ +L A + L +L L+L +
Sbjct: 185 LKVLSLRSN-AGKVPASVTDVAGHLQRLSLHNDGARLVAL-NSLKKLAALRELELVACGL 242
Query: 374 TEIPYGMSELYVI-ELNLSQNEISLIGEDL--HQAPRLKILRLDEN 246
IP+ + L + EL+L N + I E L +L LRL N
Sbjct: 243 ERIPHAVFSLGALQELDLKDNHLRSIEEILSFQHCRKLVTLRLWHN 288
>BC033039-1|AAH33039.1| 927|Homo sapiens LGR4 protein protein.
Length = 927
Score = 76.6 bits (180), Expect = 9e-14
Identities = 52/170 (30%), Positives = 89/170 (52%), Gaps = 6/170 (3%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDD-LSKLKHLKQLNLDSNKLQALP-ESLIN 555
+LK +P + L++L L N ++ +P+D L L+ L LD N L +P L N
Sbjct: 92 QLKTVPSEAIRGLSALQSLRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVHHLSN 151
Query: 554 LKKLEVLNISNNFVQTLP-VCLKNLNNLKQVYASNNKLQAFPKQIL-GLQSLDVLDLSHN 381
L L+ L ++ N + ++P NL++L ++ NNK+++ + GL +L+ LDL++N
Sbjct: 152 LPTLQALTLALNKISSIPDFAFTNLSSLVVLHLHNNKIRSLSQHCFDGLDNLETLDLNYN 211
Query: 380 KITEIPYGMSELYVI-ELNLSQNEISLIGEDLHQA-PRLKILRLDENCLS 237
+ E P + L + EL N IS+I + P L+ + L +N LS
Sbjct: 212 NLGEFPQAIKALPSLKELGFHSNSISVIPDGAFDGNPLLRTIHLYDNPLS 261
Score = 59.3 bits (137), Expect = 1e-08
Identities = 45/136 (33%), Positives = 75/136 (55%), Gaps = 5/136 (3%)
Frame = -2
Query: 692 CDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQAL-PESLINLKKLEVLNISNNF 516
CD R +D S L+ +P+ LS + L L N L + P++L LK+L+VL + NN
Sbjct: 35 CDGDRRVDCSGKGLTAVPEGLSAFT--QALQLAGNDLSFIHPKALSGLKELKVLTLQNNQ 92
Query: 515 VQTLP-VCLKNLNNLKQVYASNNKLQAFPKQIL-GLQSLDVLDLSHNKITEIP-YGMSEL 345
++T+P ++ L+ L+ + N + + P+ GL L L L N +TE+P + +S L
Sbjct: 93 LKTVPSEAIRGLSALQSLRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVHHLSNL 152
Query: 344 YVIE-LNLSQNEISLI 300
++ L L+ N+IS I
Sbjct: 153 PTLQALTLALNKISSI 168
Score = 52.4 bits (120), Expect = 2e-06
Identities = 32/103 (31%), Positives = 56/103 (54%), Gaps = 2/103 (1%)
Frame = -2
Query: 734 DCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPD-DLSKLKHLKQLNLDSNKLQALPESLI 558
D L E+P+ S L+ L L+ NK+S +PD + L L L+L +NK+++L +
Sbjct: 138 DNSLTEVPVHHLSNLPTLQALTLALNKISSIPDFAFTNLSSLVVLHLHNNKIRSLSQHCF 197
Query: 557 N-LKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFP 432
+ L LE L+++ N + P +K L +LK++ +N + P
Sbjct: 198 DGLDNLETLDLNYNNLGEFPQAIKALPSLKELGFHSNSISVIP 240
Score = 45.2 bits (102), Expect = 2e-04
Identities = 45/153 (29%), Positives = 70/153 (45%), Gaps = 5/153 (3%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDD-LSKLKHLKQLNLDSNKLQALPESLI-NLKKLEVLNISN-NFV 513
L+ L N +SV+PD L+ ++L N L + S NL L L I + V
Sbjct: 226 LKELGFHSNSISVIPDGAFDGNPLLRTIHLYDNPLSFVGNSAFHNLSDLHSLVIRGASMV 285
Query: 512 QTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQS-LDVLDLSHNKITEIPYGMSELYVI 336
Q P L +L+ + + K+ + P + Q L LDLS+N I ++P +
Sbjct: 286 QQFPN-LTGTVHLESLTLTGTKISSIPNNLCQEQKMLRTLDLSYNNIRDLPSFNGCHALE 344
Query: 335 ELNLSQNEISLIGEDLHQA-PRLKILRLDENCL 240
E++L +N+I I E Q L+IL L N +
Sbjct: 345 EISLQRNQIYQIKEGTFQGLISLRILDLSRNLI 377
>AB209743-1|BAD92980.1| 1032|Homo sapiens Leucine-rich
repeat-containing G protein-coupled receptor 4 precursor
variant protein.
Length = 1032
Score = 76.6 bits (180), Expect = 9e-14
Identities = 52/170 (30%), Positives = 89/170 (52%), Gaps = 6/170 (3%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDD-LSKLKHLKQLNLDSNKLQALP-ESLIN 555
+LK +P + L++L L N ++ +P+D L L+ L LD N L +P L N
Sbjct: 197 QLKTVPSEAIRGLSALQSLRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVHPLSN 256
Query: 554 LKKLEVLNISNNFVQTLP-VCLKNLNNLKQVYASNNKLQAFPKQIL-GLQSLDVLDLSHN 381
L L+ L ++ N + ++P NL++L ++ NNK+++ + GL +L+ LDL++N
Sbjct: 257 LPTLQALTLALNKISSIPDFAFTNLSSLVVLHLHNNKIRSLSQHCFDGLDNLETLDLNYN 316
Query: 380 KITEIPYGMSELYVI-ELNLSQNEISLIGEDLHQA-PRLKILRLDENCLS 237
+ E P + L + EL N IS+I + P L+ + L +N LS
Sbjct: 317 NLGEFPQAIKALPSLKELGFHSNSISVIPDGAFDGNPLLRTIHLYDNPLS 366
Score = 65.3 bits (152), Expect = 2e-10
Identities = 49/151 (32%), Positives = 82/151 (54%), Gaps = 6/151 (3%)
Frame = -2
Query: 734 DCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSK-LKHLKQLNLDSNKLQAL-PESL 561
DC K + L + LD+S N ++ LP+D K L++L L N L + P++L
Sbjct: 123 DCSGKGLTAVPEGLSAFTQALDISMNNITQLPEDAFKNFPFLEELQLAGNDLSFIHPKAL 182
Query: 560 INLKKLEVLNISNNFVQTLP-VCLKNLNNLKQVYASNNKLQAFPKQIL-GLQSLDVLDLS 387
LK+L+VL + NN ++T+P ++ L+ L+ + N + + P+ GL L L L
Sbjct: 183 SGLKELKVLTLQNNQLKTVPSEAIRGLSALQSLRLDANHITSVPEDSFEGLVQLRHLWLD 242
Query: 386 HNKITEIP-YGMSELYVIE-LNLSQNEISLI 300
N +TE+P + +S L ++ L L+ N+IS I
Sbjct: 243 DNSLTEVPVHPLSNLPTLQALTLALNKISSI 273
Score = 52.8 bits (121), Expect = 1e-06
Identities = 32/103 (31%), Positives = 56/103 (54%), Gaps = 2/103 (1%)
Frame = -2
Query: 734 DCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPD-DLSKLKHLKQLNLDSNKLQALPESLI 558
D L E+P+ S L+ L L+ NK+S +PD + L L L+L +NK+++L +
Sbjct: 243 DNSLTEVPVHPLSNLPTLQALTLALNKISSIPDFAFTNLSSLVVLHLHNNKIRSLSQHCF 302
Query: 557 N-LKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFP 432
+ L LE L+++ N + P +K L +LK++ +N + P
Sbjct: 303 DGLDNLETLDLNYNNLGEFPQAIKALPSLKELGFHSNSISVIP 345
Score = 45.2 bits (102), Expect = 2e-04
Identities = 45/153 (29%), Positives = 70/153 (45%), Gaps = 5/153 (3%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDD-LSKLKHLKQLNLDSNKLQALPESLI-NLKKLEVLNISN-NFV 513
L+ L N +SV+PD L+ ++L N L + S NL L L I + V
Sbjct: 331 LKELGFHSNSISVIPDGAFDGNPLLRTIHLYDNPLSFVGNSAFHNLSDLHSLVIRGASMV 390
Query: 512 QTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQS-LDVLDLSHNKITEIPYGMSELYVI 336
Q P L +L+ + + K+ + P + Q L LDLS+N I ++P +
Sbjct: 391 QQFPN-LTGTVHLESLTLTGTKISSIPNNLCQEQKMLRTLDLSYNNIRDLPSFNGCHALE 449
Query: 335 ELNLSQNEISLIGEDLHQA-PRLKILRLDENCL 240
E++L +N+I I E Q L+IL L N +
Sbjct: 450 EISLQRNQIYQIKEGTFQGLISLRILDLSRNLI 482
>BC106893-1|AAI06894.1| 250|Homo sapiens LRRC10 protein protein.
Length = 250
Score = 75.8 bits (178), Expect = 2e-13
Identities = 57/191 (29%), Positives = 96/191 (50%), Gaps = 1/191 (0%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESL 561
++ +L+ P+ V S ++++ L LS N L+ LP +L +L++L+ L LD N +ALP+ +
Sbjct: 9 LSGSQLRRFPLHVCSFRELVK-LYLSDNHLNSLPPELGQLQNLQILALDFNNFKALPQVV 67
Query: 560 INLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHN 381
LK+L +L + NN + LP L L NL+ ++ N L P + L L L N
Sbjct: 68 CTLKQLCILYLGNNKLCDLPSELSLLQNLRTLWIEANCLTQLPDVVCELSLLKTLHAGSN 127
Query: 380 KITEIPYGMSELYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRD 204
+ +P + L + + LS N ++ L P L+++ +D N + PSL
Sbjct: 128 ALRLLPGQLRRLQELRTIWLSGNRLTDFPTVLLHMPFLEVIDVDWNSI---RYFPSLAHL 184
Query: 203 SKIHTVSVDGN 171
S + V D N
Sbjct: 185 SSLKLVIYDHN 195
Score = 69.7 bits (163), Expect = 1e-11
Identities = 49/169 (28%), Positives = 83/169 (49%), Gaps = 1/169 (0%)
Frame = -2
Query: 674 LDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTLPVC 495
+DLS ++L P + + L +L L N L +LP L L+ L++L + N + LP
Sbjct: 7 VDLSGSQLRRFPLHVCSFRELVKLYLSDNHLNSLPPELGQLQNLQILALDFNNFKALPQV 66
Query: 494 LKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVIE-LNLSQ 318
+ L L +Y NNKL P ++ LQ+L L + N +T++P + EL +++ L+
Sbjct: 67 VCTLKQLCILYLGNNKLCDLPSELSLLQNLRTLWIEANCLTQLPDVVCELSLLKTLHAGS 126
Query: 317 NEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIHTVSVDGN 171
N + L+ L + L+ + L N L + LL + + VD N
Sbjct: 127 NALRLLPGQLRRLQELRTIWLSGN--RLTDFPTVLLHMPFLEVIDVDWN 173
>BC106892-1|AAI06893.1| 249|Homo sapiens LRRC10 protein protein.
Length = 249
Score = 75.8 bits (178), Expect = 2e-13
Identities = 57/191 (29%), Positives = 96/191 (50%), Gaps = 1/191 (0%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESL 561
++ +L+ P+ V S ++++ L LS N L+ LP +L +L++L+ L LD N +ALP+ +
Sbjct: 8 LSGSQLRRFPLHVCSFRELVK-LYLSDNHLNSLPPELGQLQNLQILALDFNNFKALPQVV 66
Query: 560 INLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHN 381
LK+L +L + NN + LP L L NL+ ++ N L P + L L L N
Sbjct: 67 CTLKQLCILYLGNNKLCDLPSELSLLQNLRTLWIEANCLTQLPDVVCELSLLKTLHAGSN 126
Query: 380 KITEIPYGMSELYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRD 204
+ +P + L + + LS N ++ L P L+++ +D N + PSL
Sbjct: 127 ALRLLPGQLRRLQELRTIWLSGNRLTDFPTVLLHMPFLEVIDVDWNSI---RYFPSLAHL 183
Query: 203 SKIHTVSVDGN 171
S + V D N
Sbjct: 184 SSLKLVIYDHN 194
Score = 69.7 bits (163), Expect = 1e-11
Identities = 49/169 (28%), Positives = 83/169 (49%), Gaps = 1/169 (0%)
Frame = -2
Query: 674 LDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTLPVC 495
+DLS ++L P + + L +L L N L +LP L L+ L++L + N + LP
Sbjct: 6 VDLSGSQLRRFPLHVCSFRELVKLYLSDNHLNSLPPELGQLQNLQILALDFNNFKALPQV 65
Query: 494 LKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVIE-LNLSQ 318
+ L L +Y NNKL P ++ LQ+L L + N +T++P + EL +++ L+
Sbjct: 66 VCTLKQLCILYLGNNKLCDLPSELSLLQNLRTLWIEANCLTQLPDVVCELSLLKTLHAGS 125
Query: 317 NEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIHTVSVDGN 171
N + L+ L + L+ + L N L + LL + + VD N
Sbjct: 126 NALRLLPGQLRRLQELRTIWLSGN--RLTDFPTVLLHMPFLEVIDVDWN 172
>BC090881-1|AAH90881.1| 277|Homo sapiens leucine rich repeat
containing 10 protein.
Length = 277
Score = 75.8 bits (178), Expect = 2e-13
Identities = 57/191 (29%), Positives = 96/191 (50%), Gaps = 1/191 (0%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESL 561
++ +L+ P+ V S ++++ L LS N L+ LP +L +L++L+ L LD N +ALP+ +
Sbjct: 36 LSGSQLRRFPLHVCSFRELVK-LYLSDNHLNSLPPELGQLQNLQILALDFNNFKALPQVV 94
Query: 560 INLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHN 381
LK+L +L + NN + LP L L NL+ ++ N L P + L L L N
Sbjct: 95 CTLKQLCILYLGNNKLCDLPSELSLLQNLRTLWIEANCLTQLPDVVCELSLLKTLHAGSN 154
Query: 380 KITEIPYGMSELYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRD 204
+ +P + L + + LS N ++ L P L+++ +D N + PSL
Sbjct: 155 ALRLLPGQLRRLQELRTIWLSGNRLTDFPTVLLHMPFLEVIDVDWNSI---RYFPSLAHL 211
Query: 203 SKIHTVSVDGN 171
S + V D N
Sbjct: 212 SSLKLVIYDHN 222
Score = 70.5 bits (165), Expect = 6e-12
Identities = 53/186 (28%), Positives = 91/186 (48%), Gaps = 1/186 (0%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKK 546
L+E+P+D + +DLS ++L P + + L +L L N L +LP L L+
Sbjct: 25 LREMPLD--------KMVDLSGSQLRRFPLHVCSFRELVKLYLSDNHLNSLPPELGQLQN 76
Query: 545 LEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEI 366
L++L + N + LP + L L +Y NNKL P ++ LQ+L L + N +T++
Sbjct: 77 LQILALDFNNFKALPQVVCTLKQLCILYLGNNKLCDLPSELSLLQNLRTLWIEANCLTQL 136
Query: 365 PYGMSELYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIHT 189
P + EL +++ L+ N + L+ L + L+ + L N L + LL +
Sbjct: 137 PDVVCELSLLKTLHAGSNALRLLPGQLRRLQELRTIWLSGN--RLTDFPTVLLHMPFLEV 194
Query: 188 VSVDGN 171
+ VD N
Sbjct: 195 IDVDWN 200
>AK123908-1|BAC85724.1| 250|Homo sapiens protein ( Homo sapiens
cDNA FLJ41914 fis, clone PERIC2001228. ).
Length = 250
Score = 75.8 bits (178), Expect = 2e-13
Identities = 57/191 (29%), Positives = 96/191 (50%), Gaps = 1/191 (0%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESL 561
++ +L+ P+ V S ++++ L LS N L+ LP +L +L++L+ L LD N +ALP+ +
Sbjct: 9 LSGSQLRRFPLHVCSFRELVK-LYLSDNHLNSLPPELGQLQNLQILALDFNNFKALPQVV 67
Query: 560 INLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHN 381
LK+L +L + NN + LP L L NL+ ++ N L P + L L L N
Sbjct: 68 CTLKQLCILYLGNNKLCDLPSELSLLQNLRTLWIEANCLTQLPDVVCELSLLKTLHAGSN 127
Query: 380 KITEIPYGMSELYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRD 204
+ +P + L + + LS N ++ L P L+++ +D N + PSL
Sbjct: 128 ALRLLPGQLRRLQELRTIWLSGNRLTDFPTVLLHMPFLEVIDVDWNSI---RYFPSLAHL 184
Query: 203 SKIHTVSVDGN 171
S + V D N
Sbjct: 185 SSLKLVIYDHN 195
Score = 69.7 bits (163), Expect = 1e-11
Identities = 49/169 (28%), Positives = 83/169 (49%), Gaps = 1/169 (0%)
Frame = -2
Query: 674 LDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTLPVC 495
+DLS ++L P + + L +L L N L +LP L L+ L++L + N + LP
Sbjct: 7 VDLSGSQLRRFPLHVCSFRELVKLYLSDNHLNSLPPELGQLQNLQILALDFNNFKALPQV 66
Query: 494 LKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVIE-LNLSQ 318
+ L L +Y NNKL P ++ LQ+L L + N +T++P + EL +++ L+
Sbjct: 67 VCTLKQLCILYLGNNKLCDLPSELSLLQNLRTLWIEANCLTQLPDVVCELSLLKTLHAGS 126
Query: 317 NEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIHTVSVDGN 171
N + L+ L + L+ + L N L + LL + + VD N
Sbjct: 127 NALRLLPGQLRRLQELRTIWLSGN--RLTDFPTVLLHMPFLEVIDVDWN 173
>AF346711-1|AAK31153.1| 951|Homo sapiens G-protein couple receptor
protein.
Length = 951
Score = 74.9 bits (176), Expect = 3e-13
Identities = 52/170 (30%), Positives = 88/170 (51%), Gaps = 6/170 (3%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDD-LSKLKHLKQLNLDSNKLQALP-ESLIN 555
+LK +P + L++L L N ++ +P+D L L+ L LD N L +P L N
Sbjct: 116 QLKTVPSEAIRGLSALQSLRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVHPLSN 175
Query: 554 LKKLEVLNISNNFVQTLP-VCLKNLNNLKQVYASNNKLQAFPKQIL-GLQSLDVLDLSHN 381
L L+ L ++ N + ++P NL++L ++ NNK++ + GL +L+ LDLS+N
Sbjct: 176 LPTLQALTLALNKISSIPDFAFTNLSSLVVLHLHNNKIRGLSQHCFDGLDNLETLDLSYN 235
Query: 380 KITEIPYGM-SELYVIELNLSQNEISLIGEDLHQA-PRLKILRLDENCLS 237
+ E P + + + EL N IS+I + P L+ + L +N LS
Sbjct: 236 NLGEFPQAIKARPSLKELGFHSNSISVIPDGAFDGNPLLRTIHLYDNPLS 285
Score = 65.3 bits (152), Expect = 2e-10
Identities = 49/151 (32%), Positives = 82/151 (54%), Gaps = 6/151 (3%)
Frame = -2
Query: 734 DCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSK-LKHLKQLNLDSNKLQAL-PESL 561
DC K + L + LD+S N ++ LP+D K L++L L N L + P++L
Sbjct: 42 DCSGKGLTAVPEGLSAFTQALDISMNNITQLPEDAFKNFPFLEELQLAGNDLSFIHPKAL 101
Query: 560 INLKKLEVLNISNNFVQTLP-VCLKNLNNLKQVYASNNKLQAFPKQIL-GLQSLDVLDLS 387
LK+L+VL + NN ++T+P ++ L+ L+ + N + + P+ GL L L L
Sbjct: 102 SGLKELKVLTLQNNQLKTVPSEAIRGLSALQSLRLDANHITSVPEDSFEGLVQLRHLWLD 161
Query: 386 HNKITEIP-YGMSELYVIE-LNLSQNEISLI 300
N +TE+P + +S L ++ L L+ N+IS I
Sbjct: 162 DNSLTEVPVHPLSNLPTLQALTLALNKISSI 192
Score = 51.2 bits (117), Expect = 4e-06
Identities = 32/103 (31%), Positives = 54/103 (52%), Gaps = 2/103 (1%)
Frame = -2
Query: 734 DCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPD-DLSKLKHLKQLNLDSNKLQALPESLI 558
D L E+P+ S L+ L L+ NK+S +PD + L L L+L +NK++ L +
Sbjct: 162 DNSLTEVPVHPLSNLPTLQALTLALNKISSIPDFAFTNLSSLVVLHLHNNKIRGLSQHCF 221
Query: 557 N-LKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFP 432
+ L LE L++S N + P +K +LK++ +N + P
Sbjct: 222 DGLDNLETLDLSYNNLGEFPQAIKARPSLKELGFHSNSISVIP 264
Score = 45.2 bits (102), Expect = 2e-04
Identities = 45/153 (29%), Positives = 70/153 (45%), Gaps = 5/153 (3%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDD-LSKLKHLKQLNLDSNKLQALPESLI-NLKKLEVLNISN-NFV 513
L+ L N +SV+PD L+ ++L N L + S NL L L I + V
Sbjct: 250 LKELGFHSNSISVIPDGAFDGNPLLRTIHLYDNPLSFVGNSAFHNLSDLHSLVIRGASMV 309
Query: 512 QTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQS-LDVLDLSHNKITEIPYGMSELYVI 336
Q P L +L+ + + K+ + P + Q L LDLS+N I ++P +
Sbjct: 310 QQFPN-LTGTVHLESLTLTGTKISSIPNNLCQEQKMLRTLDLSYNNIRDLPSFNGCHALE 368
Query: 335 ELNLSQNEISLIGEDLHQA-PRLKILRLDENCL 240
E++L +N+I I E Q L+IL L N +
Sbjct: 369 EISLQRNQIYQIKEGTFQGLISLRILDLSRNLI 401
>AF257182-1|AAF68989.1| 951|Homo sapiens G-protein-coupled receptor
48 protein.
Length = 951
Score = 74.9 bits (176), Expect = 3e-13
Identities = 52/170 (30%), Positives = 88/170 (51%), Gaps = 6/170 (3%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDD-LSKLKHLKQLNLDSNKLQALP-ESLIN 555
+LK +P + L++L L N ++ +P+D L L+ L LD N L +P L N
Sbjct: 116 QLKTVPSEAIRGLSALQSLRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVHPLSN 175
Query: 554 LKKLEVLNISNNFVQTLP-VCLKNLNNLKQVYASNNKLQAFPKQIL-GLQSLDVLDLSHN 381
L L+ L ++ N + ++P NL++L ++ NNK++ + GL +L+ LDLS+N
Sbjct: 176 LPTLQALTLALNKISSIPDFAFTNLSSLVVLHLHNNKIRGLSQHCFDGLDNLETLDLSYN 235
Query: 380 KITEIPYGM-SELYVIELNLSQNEISLIGEDLHQA-PRLKILRLDENCLS 237
+ E P + + + EL N IS+I + P L+ + L +N LS
Sbjct: 236 NLGEFPQAIKARPSLKELGFHSNSISVIPDGAFDGNPLLRTIHLYDNPLS 285
Score = 65.3 bits (152), Expect = 2e-10
Identities = 49/151 (32%), Positives = 82/151 (54%), Gaps = 6/151 (3%)
Frame = -2
Query: 734 DCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSK-LKHLKQLNLDSNKLQAL-PESL 561
DC K + L + LD+S N ++ LP+D K L++L L N L + P++L
Sbjct: 42 DCSGKGLTAVPEGLSAFTQALDISMNNITQLPEDAFKNFPFLEELQLAGNDLSFIHPKAL 101
Query: 560 INLKKLEVLNISNNFVQTLP-VCLKNLNNLKQVYASNNKLQAFPKQIL-GLQSLDVLDLS 387
LK+L+VL + NN ++T+P ++ L+ L+ + N + + P+ GL L L L
Sbjct: 102 SGLKELKVLTLQNNQLKTVPSEAIRGLSALQSLRLDANHITSVPEDSFEGLVQLRHLWLD 161
Query: 386 HNKITEIP-YGMSELYVIE-LNLSQNEISLI 300
N +TE+P + +S L ++ L L+ N+IS I
Sbjct: 162 DNSLTEVPVHPLSNLPTLQALTLALNKISSI 192
Score = 51.2 bits (117), Expect = 4e-06
Identities = 32/103 (31%), Positives = 54/103 (52%), Gaps = 2/103 (1%)
Frame = -2
Query: 734 DCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPD-DLSKLKHLKQLNLDSNKLQALPESLI 558
D L E+P+ S L+ L L+ NK+S +PD + L L L+L +NK++ L +
Sbjct: 162 DNSLTEVPVHPLSNLPTLQALTLALNKISSIPDFAFTNLSSLVVLHLHNNKIRGLSQHCF 221
Query: 557 N-LKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFP 432
+ L LE L++S N + P +K +LK++ +N + P
Sbjct: 222 DGLDNLETLDLSYNNLGEFPQAIKARPSLKELGFHSNSISVIP 264
Score = 44.4 bits (100), Expect = 4e-04
Identities = 45/153 (29%), Positives = 70/153 (45%), Gaps = 5/153 (3%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDD-LSKLKHLKQLNLDSNKLQALPESLI-NLKKLEVLNISN-NFV 513
L+ L N +SV+PD L+ ++L N L + S NL L L I + V
Sbjct: 250 LKELGFHSNSISVIPDGAFDGNPLLRTIHLYDNPLSFVGNSASHNLSDLHSLVIRGASMV 309
Query: 512 QTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQS-LDVLDLSHNKITEIPYGMSELYVI 336
Q P L +L+ + + K+ + P + Q L LDLS+N I ++P +
Sbjct: 310 QQFPN-LTGTVHLESLTLTGTKISSIPNNLCQEQKMLRTLDLSYNNIRDLPSFNGCHALE 368
Query: 335 ELNLSQNEISLIGEDLHQA-PRLKILRLDENCL 240
E++L +N+I I E Q L+IL L N +
Sbjct: 369 EISLQRNQIYQIKEGTFQGLISLRILDLSRNLI 401
>AY358112-1|AAQ88479.1| 802|Homo sapiens ITLT6413 protein.
Length = 802
Score = 74.1 bits (174), Expect = 5e-13
Identities = 50/176 (28%), Positives = 92/176 (52%), Gaps = 2/176 (1%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPE-SLINLKKLEVLNISNNFVQT 507
L++L+L L +P + L +L +L+L N L+ + E S +L+ L L + +N +
Sbjct: 587 LKSLELISCDLERIPHSIFSLNNLHELDLRENNLKTVEEISFQHLQNLSCLKLWHNNIAY 646
Query: 506 LPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVIE-L 330
+P + L+NL+Q+ +N ++ P Q+ L LDLS+N +T IP + L ++
Sbjct: 647 IPAQIGALSNLEQLSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQYF 706
Query: 329 NLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIHTVSVDGNLFE 162
++ N I ++ + L Q +L+ L L +N SL + P + S + + + GN E
Sbjct: 707 AVTNNNIEMLPDGLFQCKKLQCLLLGKN--SLMNLSPHVGELSNLTHLELIGNYLE 760
Score = 70.5 bits (165), Expect = 6e-12
Identities = 38/128 (29%), Positives = 70/128 (54%), Gaps = 2/128 (1%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKK 546
++ +P+ +F LC L LDLS N L+ +P+++ L +L+ + +N ++ LP+ L KK
Sbjct: 667 IENLPLQLF-LCTKLHYLDLSYNHLTFIPEEIQYLSNLQYFAVTNNNIEMLPDGLFQCKK 725
Query: 545 LEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSL--DVLDLSHNKIT 372
L+ L + N + L + L+NL + N L+ P ++ G QSL + L + N +
Sbjct: 726 LQCLLLGKNSLMNLSPHVGELSNLTHLELIGNYLETLPPELEGCQSLKRNCLIVEENLLN 785
Query: 371 EIPYGMSE 348
+P ++E
Sbjct: 786 TLPLPVTE 793
Score = 47.2 bits (107), Expect = 6e-05
Identities = 33/118 (27%), Positives = 52/118 (44%)
Frame = -2
Query: 716 IPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEV 537
IP + +L + L L L N + LP L L L+L N L +PE + L L+
Sbjct: 647 IPAQIGALSN-LEQLSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQY 705
Query: 536 LNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIP 363
++NN ++ LP L L+ + N L + L +L L+L N + +P
Sbjct: 706 FAVTNNNIEMLPDGLFQCKKLQCLLLGKNSLMNLSPHVGELSNLTHLELIGNYLETLP 763
Score = 45.2 bits (102), Expect = 2e-04
Identities = 58/217 (26%), Positives = 101/217 (46%), Gaps = 14/217 (6%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSK--------LKHLKQLNLDSNKLQAL 573
++ +IP VF L + L+ L LS VLP+ LS LK+L+ L L S+ L +
Sbjct: 498 EMGKIPRWVFHLKN-LKELYLSG---CVLPEQLSTMQLEGFQDLKNLRTLYLKSS-LSRI 552
Query: 572 PESLINL-KKLEVLNISNNFVQTLPVC-LKNLNNLKQVYASNNKLQAFPKQILGLQSLDV 399
P+ + +L L+ L++ N + + + LK + NLK + + L+ P I L +L
Sbjct: 553 PQVVTDLLPSLQKLSLDNEGSKLVVLNNLKKMVNLKSLELISCDLERIPHSIFSLNNLHE 612
Query: 398 LDLSHNKITEI-PYGMSELYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEI 225
LDL N + + L + L L N I+ I + L+ L LD N +++ +
Sbjct: 613 LDLRENNLKTVEEISFQHLQNLSCLKLWHNNIAYIPAQIGALSNLEQLSLDHN--NIENL 670
Query: 224 KPSLLRDSKIHTVSVDGN--LFEPKQLAXLEGYNEYS 120
L +K+H + + N F P+++ L ++
Sbjct: 671 PLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQYFA 707
Score = 31.9 bits (69), Expect = 2.5
Identities = 30/132 (22%), Positives = 58/132 (43%), Gaps = 7/132 (5%)
Frame = -2
Query: 584 LQALPESLINLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQA-FPKQILGLQS 408
L LP+++ L ++EVL++ LP + L NLK++ ++ L P ++
Sbjct: 429 LNGLPDNVFELTEMEVLSLELIPEVKLPSAVSQLVNLKELRVYHSSLVVDHPALAFLEEN 488
Query: 407 LDVLDLSHNKITEIP------YGMSELYVIELNLSQNEISLIGEDLHQAPRLKILRLDEN 246
L +L L ++ +IP + ELY+ L + ++ E L+ L L +
Sbjct: 489 LKILRLKFTEMGKIPRWVFHLKNLKELYLSGCVLPEQLSTMQLEGFQDLKNLRTLYLKSS 548
Query: 245 CLSLDEIKPSLL 210
+ ++ LL
Sbjct: 549 LSRIPQVVTDLL 560
>BC139921-1|AAI39922.1| 414|Homo sapiens peptidylprolyl isomerase
(cyclophilin)-like 5 protein.
Length = 414
Score = 73.7 bits (173), Expect = 6e-13
Identities = 55/175 (31%), Positives = 87/175 (49%), Gaps = 4/175 (2%)
Frame = -2
Query: 716 IPIDVFSLC-DVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINL---K 549
+ +D+ LC LR LDLS N + LP + L HL++LNL+ N L++ +L + K
Sbjct: 167 VRVDMRMLCLKSLRKLDLSHNHIKKLPATIGDLIHLQELNLNDNHLESFSVALCHSTLQK 226
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITE 369
L L++S N ++ LPV L LK + +N+L FP +I L +L L + NK+
Sbjct: 227 SLRSLDLSKNKIKALPVQFCQLQELKNLKLDDNELIQFPCKIGQLINLRFLSAARNKLPF 286
Query: 368 IPYGMSELYVIELNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRD 204
+P SE NLS + L G Q L +++L L+ ++L +
Sbjct: 287 LP---SEF----RNLSLEYLDLFGNTFEQPKVLPVIKLQAPLTLLESSARTILHN 334
Score = 55.2 bits (127), Expect = 2e-07
Identities = 45/128 (35%), Positives = 68/128 (53%), Gaps = 5/128 (3%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTL 504
LR+LDLSKNK+ LP +L+ LK L LD N+L P + L L L+ + N + L
Sbjct: 228 LRSLDLSKNKIKALPVQFCQLQELKNLKLDDNELIQFPCKIGQLINLRFLSAARNKLPFL 287
Query: 503 PVCLKNLNNLKQVYASNNKLQAFPK--QILGLQS-LDVLDLSHNKI--TEIPYGMSELYV 339
P +NL +L+ + N + PK ++ LQ+ L +L+ S I IPYG ++
Sbjct: 288 PSEFRNL-SLEYLDLFGNTFEQ-PKVLPVIKLQAPLTLLESSARTILHNRIPYGS---HI 342
Query: 338 IELNLSQN 315
I +L Q+
Sbjct: 343 IPFHLCQD 350
Score = 53.6 bits (123), Expect = 7e-07
Identities = 39/118 (33%), Positives = 63/118 (53%), Gaps = 3/118 (2%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKL---SVLPDDLSKLKHLKQLNLDSNKLQALPESLIN 555
+K++P + L L+ L+L+ N L SV + K L+ L+L NK++ALP
Sbjct: 189 IKKLPATIGDLIH-LQELNLNDNHLESFSVALCHSTLQKSLRSLDLSKNKIKALPVQFCQ 247
Query: 554 LKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHN 381
L++L+ L + +N + P + L NL+ + A+ NKL P + L SL+ LDL N
Sbjct: 248 LQELKNLKLDDNELIQFPCKIGQLINLRFLSAARNKLPFLPSEFRNL-SLEYLDLFGN 304
Score = 36.7 bits (81), Expect = 0.087
Identities = 31/88 (35%), Positives = 48/88 (54%), Gaps = 2/88 (2%)
Frame = -2
Query: 479 NLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSEL-YVIELNLSQNEISL 303
+L+ + S L ++L L+SL LDLSHN I ++P + +L ++ ELNL+ N +
Sbjct: 155 SLEHLQTSYCGLVRVDMRMLCLKSLRKLDLSHNHIKKLPATIGDLIHLQELNLNDNHLES 214
Query: 302 IGEDLHQAPRLKILR-LDENCLSLDEIK 222
L + K LR LD LS ++IK
Sbjct: 215 FSVALCHSTLQKSLRSLD---LSKNKIK 239
>AY052405-1|AAL11430.1| 414|Homo sapiens 4-1BB-mediated signaling
molecule protein.
Length = 414
Score = 73.7 bits (173), Expect = 6e-13
Identities = 55/175 (31%), Positives = 87/175 (49%), Gaps = 4/175 (2%)
Frame = -2
Query: 716 IPIDVFSLC-DVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINL---K 549
+ +D+ LC LR LDLS N + LP + L HL++LNL+ N L++ +L + K
Sbjct: 167 VRVDMRMLCLKSLRKLDLSHNHIKKLPATIGDLIHLQELNLNDNHLESFSVALCHSTLQK 226
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITE 369
L L++S N ++ LPV L LK + +N+L FP +I L +L L + NK+
Sbjct: 227 SLRSLDLSKNKIKALPVQFCQLQELKNLKLDDNELIQFPCKIGQLINLRFLSAARNKLPF 286
Query: 368 IPYGMSELYVIELNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRD 204
+P SE NLS + L G Q L +++L L+ ++L +
Sbjct: 287 LP---SEF----RNLSLEYLDLFGNTFEQPKVLPVIKLQAPLTLLESSARTILHN 334
Score = 55.2 bits (127), Expect = 2e-07
Identities = 45/128 (35%), Positives = 68/128 (53%), Gaps = 5/128 (3%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTL 504
LR+LDLSKNK+ LP +L+ LK L LD N+L P + L L L+ + N + L
Sbjct: 228 LRSLDLSKNKIKALPVQFCQLQELKNLKLDDNELIQFPCKIGQLINLRFLSAARNKLPFL 287
Query: 503 PVCLKNLNNLKQVYASNNKLQAFPK--QILGLQS-LDVLDLSHNKI--TEIPYGMSELYV 339
P +NL +L+ + N + PK ++ LQ+ L +L+ S I IPYG ++
Sbjct: 288 PSEFRNL-SLEYLDLFGNTFEQ-PKVLPVIKLQAPLTLLESSARTILHNRIPYGS---HI 342
Query: 338 IELNLSQN 315
I +L Q+
Sbjct: 343 IPFHLCQD 350
Score = 53.6 bits (123), Expect = 7e-07
Identities = 39/118 (33%), Positives = 63/118 (53%), Gaps = 3/118 (2%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKL---SVLPDDLSKLKHLKQLNLDSNKLQALPESLIN 555
+K++P + L L+ L+L+ N L SV + K L+ L+L NK++ALP
Sbjct: 189 IKKLPATIGDLIH-LQELNLNDNHLESFSVALCHSTLQKSLRSLDLSKNKIKALPVQFCQ 247
Query: 554 LKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHN 381
L++L+ L + +N + P + L NL+ + A+ NKL P + L SL+ LDL N
Sbjct: 248 LQELKNLKLDDNELIQFPCKIGQLINLRFLSAARNKLPFLPSEFRNL-SLEYLDLFGN 304
Score = 36.7 bits (81), Expect = 0.087
Identities = 31/88 (35%), Positives = 48/88 (54%), Gaps = 2/88 (2%)
Frame = -2
Query: 479 NLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSEL-YVIELNLSQNEISL 303
+L+ + S L ++L L+SL LDLSHN I ++P + +L ++ ELNL+ N +
Sbjct: 155 SLEHLQTSYCGLVRVDMRMLCLKSLRKLDLSHNHIKKLPATIGDLIHLQELNLNDNHLES 214
Query: 302 IGEDLHQAPRLKILR-LDENCLSLDEIK 222
L + K LR LD LS ++IK
Sbjct: 215 FSVALCHSTLQKSLRSLD---LSKNKIK 239
>D86984-1|BAA13220.2| 823|Homo sapiens KIAA0231 protein protein.
Length = 823
Score = 73.3 bits (172), Expect = 8e-13
Identities = 50/177 (28%), Positives = 92/177 (51%), Gaps = 3/177 (1%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPE--SLINLKKLEVLNISNNFVQ 510
L++L+L L +P + L +L +L+L N L+ + E S +L+ L L + +N +
Sbjct: 607 LKSLELISCDLERIPHSIFSLNNLHELDLRENNLKTVEEIISFQHLQNLSCLKLWHNNIA 666
Query: 509 TLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVIE- 333
+P + L+NL+Q+ +N ++ P Q+ L LDLS+N +T IP + L ++
Sbjct: 667 YIPAQIGALSNLEQLSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQY 726
Query: 332 LNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIHTVSVDGNLFE 162
++ N I ++ + L Q +L+ L L +N SL + P + S + + + GN E
Sbjct: 727 FAVTNNNIEMLPDGLFQCKKLQCLLLGKN--SLMNLSPHVGELSNLTHLELIGNYLE 781
Score = 70.5 bits (165), Expect = 6e-12
Identities = 38/128 (29%), Positives = 70/128 (54%), Gaps = 2/128 (1%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKK 546
++ +P+ +F LC L LDLS N L+ +P+++ L +L+ + +N ++ LP+ L KK
Sbjct: 688 IENLPLQLF-LCTKLHYLDLSYNHLTFIPEEIQYLSNLQYFAVTNNNIEMLPDGLFQCKK 746
Query: 545 LEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSL--DVLDLSHNKIT 372
L+ L + N + L + L+NL + N L+ P ++ G QSL + L + N +
Sbjct: 747 LQCLLLGKNSLMNLSPHVGELSNLTHLELIGNYLETLPPELEGCQSLKRNCLIVEENLLN 806
Query: 371 EIPYGMSE 348
+P ++E
Sbjct: 807 TLPLPVTE 814
Score = 47.2 bits (107), Expect = 6e-05
Identities = 33/118 (27%), Positives = 52/118 (44%)
Frame = -2
Query: 716 IPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEV 537
IP + +L + L L L N + LP L L L+L N L +PE + L L+
Sbjct: 668 IPAQIGALSN-LEQLSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQY 726
Query: 536 LNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIP 363
++NN ++ LP L L+ + N L + L +L L+L N + +P
Sbjct: 727 FAVTNNNIEMLPDGLFQCKKLQCLLLGKNSLMNLSPHVGELSNLTHLELIGNYLETLP 784
Score = 45.6 bits (103), Expect = 2e-04
Identities = 58/218 (26%), Positives = 104/218 (47%), Gaps = 15/218 (6%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSK--------LKHLKQLNLDSNKLQAL 573
++ +IP VF L + L+ L LS VLP+ LS LK+L+ L L S+ L +
Sbjct: 518 EMGKIPRWVFHLKN-LKELYLSG---CVLPEQLSTMQLEGFQDLKNLRTLYLKSS-LSRI 572
Query: 572 PESLINL-KKLEVLNISNNFVQTLPVC-LKNLNNLKQVYASNNKLQAFPKQILGLQSLDV 399
P+ + +L L+ L++ N + + + LK + NLK + + L+ P I L +L
Sbjct: 573 PQVVTDLLPSLQKLSLDNEGSKLVVLNNLKKMVNLKSLELISCDLERIPHSIFSLNNLHE 632
Query: 398 LDLSHNKITEIPYGMSELYVIELN---LSQNEISLIGEDLHQAPRLKILRLDENCLSLDE 228
LDL N + + +S ++ L+ L N I+ I + L+ L LD N +++
Sbjct: 633 LDLRENNLKTVEEIISFQHLQNLSCLKLWHNNIAYIPAQIGALSNLEQLSLDHN--NIEN 690
Query: 227 IKPSLLRDSKIHTVSVDGN--LFEPKQLAXLEGYNEYS 120
+ L +K+H + + N F P+++ L ++
Sbjct: 691 LPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQYFA 728
Score = 31.9 bits (69), Expect = 2.5
Identities = 30/132 (22%), Positives = 58/132 (43%), Gaps = 7/132 (5%)
Frame = -2
Query: 584 LQALPESLINLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQA-FPKQILGLQS 408
L LP+++ L ++EVL++ LP + L NLK++ ++ L P ++
Sbjct: 449 LNGLPDNVFELTEMEVLSLELIPEVKLPSAVSQLVNLKELRVYHSSLVVDHPALAFLEEN 508
Query: 407 LDVLDLSHNKITEIP------YGMSELYVIELNLSQNEISLIGEDLHQAPRLKILRLDEN 246
L +L L ++ +IP + ELY+ L + ++ E L+ L L +
Sbjct: 509 LKILRLKFTEMGKIPRWVFHLKNLKELYLSGCVLPEQLSTMQLEGFQDLKNLRTLYLKSS 568
Query: 245 CLSLDEIKPSLL 210
+ ++ LL
Sbjct: 569 LSRIPQVVTDLL 580
>BC060782-1|AAH60782.1| 803|Homo sapiens LRRC8B protein protein.
Length = 803
Score = 73.3 bits (172), Expect = 8e-13
Identities = 50/177 (28%), Positives = 92/177 (51%), Gaps = 3/177 (1%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPE--SLINLKKLEVLNISNNFVQ 510
L++L+L L +P + L +L +L+L N L+ + E S +L+ L L + +N +
Sbjct: 587 LKSLELISCDLERIPHSIFSLNNLHELDLRENNLKTVEEIISFQHLQNLSCLKLWHNNIA 646
Query: 509 TLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVIE- 333
+P + L+NL+Q+ +N ++ P Q+ L LDLS+N +T IP + L ++
Sbjct: 647 YIPAQIGALSNLEQLSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQY 706
Query: 332 LNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIHTVSVDGNLFE 162
++ N I ++ + L Q +L+ L L +N SL + P + S + + + GN E
Sbjct: 707 FAVTNNNIEMLPDGLFQCKKLQCLLLGKN--SLMNLSPHVGELSNLTHLELIGNYLE 761
Score = 70.5 bits (165), Expect = 6e-12
Identities = 38/128 (29%), Positives = 70/128 (54%), Gaps = 2/128 (1%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKK 546
++ +P+ +F LC L LDLS N L+ +P+++ L +L+ + +N ++ LP+ L KK
Sbjct: 668 IENLPLQLF-LCTKLHYLDLSYNHLTFIPEEIQYLSNLQYFAVTNNNIEMLPDGLFQCKK 726
Query: 545 LEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSL--DVLDLSHNKIT 372
L+ L + N + L + L+NL + N L+ P ++ G QSL + L + N +
Sbjct: 727 LQCLLLGKNSLMNLSPHVGELSNLTHLELIGNYLETLPPELEGCQSLKRNCLIVEENLLN 786
Query: 371 EIPYGMSE 348
+P ++E
Sbjct: 787 TLPLPVTE 794
Score = 47.2 bits (107), Expect = 6e-05
Identities = 33/118 (27%), Positives = 52/118 (44%)
Frame = -2
Query: 716 IPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEV 537
IP + +L + L L L N + LP L L L+L N L +PE + L L+
Sbjct: 648 IPAQIGALSN-LEQLSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQY 706
Query: 536 LNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIP 363
++NN ++ LP L L+ + N L + L +L L+L N + +P
Sbjct: 707 FAVTNNNIEMLPDGLFQCKKLQCLLLGKNSLMNLSPHVGELSNLTHLELIGNYLETLP 764
Score = 45.6 bits (103), Expect = 2e-04
Identities = 58/218 (26%), Positives = 104/218 (47%), Gaps = 15/218 (6%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSK--------LKHLKQLNLDSNKLQAL 573
++ +IP VF L + L+ L LS VLP+ LS LK+L+ L L S+ L +
Sbjct: 498 EMGKIPRWVFHLKN-LKELYLSG---CVLPEQLSTMQLEGFQDLKNLRTLYLKSS-LSRI 552
Query: 572 PESLINL-KKLEVLNISNNFVQTLPVC-LKNLNNLKQVYASNNKLQAFPKQILGLQSLDV 399
P+ + +L L+ L++ N + + + LK + NLK + + L+ P I L +L
Sbjct: 553 PQVVTDLLPSLQKLSLDNEGSKLVVLNNLKKMVNLKSLELISCDLERIPHSIFSLNNLHE 612
Query: 398 LDLSHNKITEIPYGMSELYVIELN---LSQNEISLIGEDLHQAPRLKILRLDENCLSLDE 228
LDL N + + +S ++ L+ L N I+ I + L+ L LD N +++
Sbjct: 613 LDLRENNLKTVEEIISFQHLQNLSCLKLWHNNIAYIPAQIGALSNLEQLSLDHN--NIEN 670
Query: 227 IKPSLLRDSKIHTVSVDGN--LFEPKQLAXLEGYNEYS 120
+ L +K+H + + N F P+++ L ++
Sbjct: 671 LPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQYFA 708
Score = 32.3 bits (70), Expect = 1.9
Identities = 36/149 (24%), Positives = 67/149 (44%), Gaps = 9/149 (6%)
Frame = -2
Query: 629 SKL-KHLK-QLNLDSNKLQALPESLINLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYAS 456
SKL K+ K ++ L L LP+++ L ++EVL++ LP + L NLK++
Sbjct: 412 SKLVKNAKDKIELHLFMLNGLPDNVFELTEMEVLSLELIPEVKLPSAVSQLVNLKELRVY 471
Query: 455 NNKLQA-FPKQILGLQSLDVLDLSHNKITEIP------YGMSELYVIELNLSQNEISLIG 297
++ L P ++L +L L ++ +IP + ELY+ L + ++
Sbjct: 472 HSSLVVDHPALAFLEENLKILRLKFTEMGKIPRWVFHLKNLKELYLSGCVLPEQLSTMQL 531
Query: 296 EDLHQAPRLKILRLDENCLSLDEIKPSLL 210
E L+ L L + + ++ LL
Sbjct: 532 EGFQDLKNLRTLYLKSSLSRIPQVVTDLL 560
>BC030607-1|AAH30607.1| 803|Homo sapiens leucine rich repeat
containing 8 family, member B protein.
Length = 803
Score = 73.3 bits (172), Expect = 8e-13
Identities = 50/177 (28%), Positives = 92/177 (51%), Gaps = 3/177 (1%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPE--SLINLKKLEVLNISNNFVQ 510
L++L+L L +P + L +L +L+L N L+ + E S +L+ L L + +N +
Sbjct: 587 LKSLELISCDLERIPHSIFSLNNLHELDLRENNLKTVEEIISFQHLQNLSCLKLWHNNIA 646
Query: 509 TLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVIE- 333
+P + L+NL+Q+ +N ++ P Q+ L LDLS+N +T IP + L ++
Sbjct: 647 YIPAQIGALSNLEQLSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQY 706
Query: 332 LNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIHTVSVDGNLFE 162
++ N I ++ + L Q +L+ L L +N SL + P + S + + + GN E
Sbjct: 707 FAVTNNNIEMLPDGLFQCKKLQCLLLGKN--SLMNLSPHVGELSNLTHLELIGNYLE 761
Score = 70.5 bits (165), Expect = 6e-12
Identities = 38/128 (29%), Positives = 70/128 (54%), Gaps = 2/128 (1%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKK 546
++ +P+ +F LC L LDLS N L+ +P+++ L +L+ + +N ++ LP+ L KK
Sbjct: 668 IENLPLQLF-LCTKLHYLDLSYNHLTFIPEEIQYLSNLQYFAVTNNNIEMLPDGLFQCKK 726
Query: 545 LEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSL--DVLDLSHNKIT 372
L+ L + N + L + L+NL + N L+ P ++ G QSL + L + N +
Sbjct: 727 LQCLLLGKNSLMNLSPHVGELSNLTHLELIGNYLETLPPELEGCQSLKRNCLIVEENLLN 786
Query: 371 EIPYGMSE 348
+P ++E
Sbjct: 787 TLPLPVTE 794
Score = 47.2 bits (107), Expect = 6e-05
Identities = 33/118 (27%), Positives = 52/118 (44%)
Frame = -2
Query: 716 IPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEV 537
IP + +L + L L L N + LP L L L+L N L +PE + L L+
Sbjct: 648 IPAQIGALSN-LEQLSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQY 706
Query: 536 LNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIP 363
++NN ++ LP L L+ + N L + L +L L+L N + +P
Sbjct: 707 FAVTNNNIEMLPDGLFQCKKLQCLLLGKNSLMNLSPHVGELSNLTHLELIGNYLETLP 764
Score = 45.6 bits (103), Expect = 2e-04
Identities = 58/218 (26%), Positives = 104/218 (47%), Gaps = 15/218 (6%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSK--------LKHLKQLNLDSNKLQAL 573
++ +IP VF L + L+ L LS VLP+ LS LK+L+ L L S+ L +
Sbjct: 498 EMGKIPRWVFHLKN-LKELYLSG---CVLPEQLSTMQLEGFQDLKNLRTLYLKSS-LSRI 552
Query: 572 PESLINL-KKLEVLNISNNFVQTLPVC-LKNLNNLKQVYASNNKLQAFPKQILGLQSLDV 399
P+ + +L L+ L++ N + + + LK + NLK + + L+ P I L +L
Sbjct: 553 PQVVTDLLPSLQKLSLDNEGSKLVVLNNLKKMVNLKSLELISCDLERIPHSIFSLNNLHE 612
Query: 398 LDLSHNKITEIPYGMSELYVIELN---LSQNEISLIGEDLHQAPRLKILRLDENCLSLDE 228
LDL N + + +S ++ L+ L N I+ I + L+ L LD N +++
Sbjct: 613 LDLRENNLKTVEEIISFQHLQNLSCLKLWHNNIAYIPAQIGALSNLEQLSLDHN--NIEN 670
Query: 227 IKPSLLRDSKIHTVSVDGN--LFEPKQLAXLEGYNEYS 120
+ L +K+H + + N F P+++ L ++
Sbjct: 671 LPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQYFA 708
Score = 31.9 bits (69), Expect = 2.5
Identities = 30/132 (22%), Positives = 58/132 (43%), Gaps = 7/132 (5%)
Frame = -2
Query: 584 LQALPESLINLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQA-FPKQILGLQS 408
L LP+++ L ++EVL++ LP + L NLK++ ++ L P ++
Sbjct: 429 LNGLPDNVFELTEMEVLSLELIPEVKLPSAVSQLVNLKELRVYHSSLVVDHPALAFLEEN 488
Query: 407 LDVLDLSHNKITEIP------YGMSELYVIELNLSQNEISLIGEDLHQAPRLKILRLDEN 246
L +L L ++ +IP + ELY+ L + ++ E L+ L L +
Sbjct: 489 LKILRLKFTEMGKIPRWVFHLKNLKELYLSGCVLPEQLSTMQLEGFQDLKNLRTLYLKSS 548
Query: 245 CLSLDEIKPSLL 210
+ ++ LL
Sbjct: 549 LSRIPQVVTDLL 560
>AL589786-1|CAH70721.1| 612|Homo sapiens leucine-rich repeats and
calponin homology (CH) domain containing 2 protein.
Length = 612
Score = 73.3 bits (172), Expect = 8e-13
Identities = 40/106 (37%), Positives = 65/106 (61%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESL 561
+++ KL IP ++ L D++ LD+S N++ VLP + KL L++LN+ N L LP+ L
Sbjct: 29 VSNNKLVSIPEEIGKLKDLME-LDISCNEIQVLPQQMGKLHSLRELNIRRNNLHVLPDEL 87
Query: 560 INLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQI 423
+L ++ L+ S N V +PVC + L++L+ + NN LQ P QI
Sbjct: 88 GDLPLVK-LDFSCNKVTEIPVCYRKLHHLQVIILDNNPLQVPPAQI 132
Score = 65.3 bits (152), Expect = 2e-10
Identities = 39/127 (30%), Positives = 73/127 (57%)
Frame = -2
Query: 614 LKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAF 435
L LN+ N L LP+ L +L L+VL +SNN + ++P + L +L ++ S N++Q
Sbjct: 2 LTYLNISRNLLSTLPKYLFDLP-LKVLVVSNNKLVSIPEEIGKLKDLMELDISCNEIQVL 60
Query: 434 PKQILGLQSLDVLDLSHNKITEIPYGMSELYVIELNLSQNEISLIGEDLHQAPRLKILRL 255
P+Q+ L SL L++ N + +P + +L +++L+ S N+++ I + L+++ L
Sbjct: 61 PQQMGKLHSLRELNIRRNNLHVLPDELGDLPLVKLDFSCNKVTEIPVCYRKLHHLQVIIL 120
Query: 254 DENCLSL 234
D N L +
Sbjct: 121 DNNPLQV 127
Score = 59.7 bits (138), Expect = 1e-08
Identities = 41/121 (33%), Positives = 66/121 (54%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKK 546
L +P +F L L+ L +S NKL +P+++ KLK L +L++ N++Q LP+ + L
Sbjct: 12 LSTLPKYLFDL--PLKVLVVSNNKLVSIPEEIGKLKDLMELDISCNEIQVLPQQMGKLHS 69
Query: 545 LEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEI 366
L LNI N + LP L +L +K + S NK+ P L L V+ L +N + ++
Sbjct: 70 LRELNIRRNNLHVLPDELGDLPLVKLDF-SCNKVTEIPVCYRKLHHLQVIILDNNPL-QV 127
Query: 365 P 363
P
Sbjct: 128 P 128
Score = 34.7 bits (76), Expect = 0.35
Identities = 19/54 (35%), Positives = 28/54 (51%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISN 522
L LD S NK++ +P KL HL+ + LD+N LQ P + K+ + N
Sbjct: 92 LVKLDFSCNKVTEIPVCYRKLHHLQVIILDNNPLQVPPAQICLKGKVHIFKYLN 145
>AL445164-1|CAI43033.1| 612|Homo sapiens leucine-rich repeats and
calponin homology (CH) domain containing 2 protein.
Length = 612
Score = 73.3 bits (172), Expect = 8e-13
Identities = 40/106 (37%), Positives = 65/106 (61%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESL 561
+++ KL IP ++ L D++ LD+S N++ VLP + KL L++LN+ N L LP+ L
Sbjct: 29 VSNNKLVSIPEEIGKLKDLME-LDISCNEIQVLPQQMGKLHSLRELNIRRNNLHVLPDEL 87
Query: 560 INLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQI 423
+L ++ L+ S N V +PVC + L++L+ + NN LQ P QI
Sbjct: 88 GDLPLVK-LDFSCNKVTEIPVCYRKLHHLQVIILDNNPLQVPPAQI 132
Score = 65.3 bits (152), Expect = 2e-10
Identities = 39/127 (30%), Positives = 73/127 (57%)
Frame = -2
Query: 614 LKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAF 435
L LN+ N L LP+ L +L L+VL +SNN + ++P + L +L ++ S N++Q
Sbjct: 2 LTYLNISRNLLSTLPKYLFDLP-LKVLVVSNNKLVSIPEEIGKLKDLMELDISCNEIQVL 60
Query: 434 PKQILGLQSLDVLDLSHNKITEIPYGMSELYVIELNLSQNEISLIGEDLHQAPRLKILRL 255
P+Q+ L SL L++ N + +P + +L +++L+ S N+++ I + L+++ L
Sbjct: 61 PQQMGKLHSLRELNIRRNNLHVLPDELGDLPLVKLDFSCNKVTEIPVCYRKLHHLQVIIL 120
Query: 254 DENCLSL 234
D N L +
Sbjct: 121 DNNPLQV 127
Score = 59.7 bits (138), Expect = 1e-08
Identities = 41/121 (33%), Positives = 66/121 (54%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKK 546
L +P +F L L+ L +S NKL +P+++ KLK L +L++ N++Q LP+ + L
Sbjct: 12 LSTLPKYLFDL--PLKVLVVSNNKLVSIPEEIGKLKDLMELDISCNEIQVLPQQMGKLHS 69
Query: 545 LEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEI 366
L LNI N + LP L +L +K + S NK+ P L L V+ L +N + ++
Sbjct: 70 LRELNIRRNNLHVLPDELGDLPLVKLDF-SCNKVTEIPVCYRKLHHLQVIILDNNPL-QV 127
Query: 365 P 363
P
Sbjct: 128 P 128
Score = 34.7 bits (76), Expect = 0.35
Identities = 19/54 (35%), Positives = 28/54 (51%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISN 522
L LD S NK++ +P KL HL+ + LD+N LQ P + K+ + N
Sbjct: 92 LVKLDFSCNKVTEIPVCYRKLHHLQVIILDNNPLQVPPAQICLKGKVHIFKYLN 145
>AL121878-2|CAI42077.1| 612|Homo sapiens leucine-rich repeats and
calponin homology (CH) domain containing 2 protein.
Length = 612
Score = 73.3 bits (172), Expect = 8e-13
Identities = 40/106 (37%), Positives = 65/106 (61%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESL 561
+++ KL IP ++ L D++ LD+S N++ VLP + KL L++LN+ N L LP+ L
Sbjct: 29 VSNNKLVSIPEEIGKLKDLME-LDISCNEIQVLPQQMGKLHSLRELNIRRNNLHVLPDEL 87
Query: 560 INLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQI 423
+L ++ L+ S N V +PVC + L++L+ + NN LQ P QI
Sbjct: 88 GDLPLVK-LDFSCNKVTEIPVCYRKLHHLQVIILDNNPLQVPPAQI 132
Score = 65.3 bits (152), Expect = 2e-10
Identities = 39/127 (30%), Positives = 73/127 (57%)
Frame = -2
Query: 614 LKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAF 435
L LN+ N L LP+ L +L L+VL +SNN + ++P + L +L ++ S N++Q
Sbjct: 2 LTYLNISRNLLSTLPKYLFDLP-LKVLVVSNNKLVSIPEEIGKLKDLMELDISCNEIQVL 60
Query: 434 PKQILGLQSLDVLDLSHNKITEIPYGMSELYVIELNLSQNEISLIGEDLHQAPRLKILRL 255
P+Q+ L SL L++ N + +P + +L +++L+ S N+++ I + L+++ L
Sbjct: 61 PQQMGKLHSLRELNIRRNNLHVLPDELGDLPLVKLDFSCNKVTEIPVCYRKLHHLQVIIL 120
Query: 254 DENCLSL 234
D N L +
Sbjct: 121 DNNPLQV 127
Score = 59.7 bits (138), Expect = 1e-08
Identities = 41/121 (33%), Positives = 66/121 (54%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKK 546
L +P +F L L+ L +S NKL +P+++ KLK L +L++ N++Q LP+ + L
Sbjct: 12 LSTLPKYLFDL--PLKVLVVSNNKLVSIPEEIGKLKDLMELDISCNEIQVLPQQMGKLHS 69
Query: 545 LEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEI 366
L LNI N + LP L +L +K + S NK+ P L L V+ L +N + ++
Sbjct: 70 LRELNIRRNNLHVLPDELGDLPLVKLDF-SCNKVTEIPVCYRKLHHLQVIILDNNPL-QV 127
Query: 365 P 363
P
Sbjct: 128 P 128
Score = 34.7 bits (76), Expect = 0.35
Identities = 19/54 (35%), Positives = 28/54 (51%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISN 522
L LD S NK++ +P KL HL+ + LD+N LQ P + K+ + N
Sbjct: 92 LVKLDFSCNKVTEIPVCYRKLHHLQVIILDNNPLQVPPAQICLKGKVHIFKYLN 145
>AF385436-1|AAM43837.1| 803|Homo sapiens T-cell activation leucine
repeat-rich protein protein.
Length = 803
Score = 73.3 bits (172), Expect = 8e-13
Identities = 50/177 (28%), Positives = 92/177 (51%), Gaps = 3/177 (1%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPE--SLINLKKLEVLNISNNFVQ 510
L++L+L L +P + L +L +L+L N L+ + E S +L+ L L + +N +
Sbjct: 587 LKSLELISCDLERIPHSIFSLNNLHELDLRENNLKTVEEIISFQHLQNLSCLKLWHNNIA 646
Query: 509 TLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVIE- 333
+P + L+NL+Q+ +N ++ P Q+ L LDLS+N +T IP + L ++
Sbjct: 647 YIPAQIGALSNLEQLSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQY 706
Query: 332 LNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIHTVSVDGNLFE 162
++ N I ++ + L Q +L+ L L +N SL + P + S + + + GN E
Sbjct: 707 FAVTNNNIEMLPDGLFQCKKLQCLLLGKN--SLMNLSPHVGELSNLTHLELIGNYLE 761
Score = 70.5 bits (165), Expect = 6e-12
Identities = 38/128 (29%), Positives = 70/128 (54%), Gaps = 2/128 (1%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKK 546
++ +P+ +F LC L LDLS N L+ +P+++ L +L+ + +N ++ LP+ L KK
Sbjct: 668 IENLPLQLF-LCTKLHYLDLSYNHLTFIPEEIQYLSNLQYFAVTNNNIEMLPDGLFQCKK 726
Query: 545 LEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSL--DVLDLSHNKIT 372
L+ L + N + L + L+NL + N L+ P ++ G QSL + L + N +
Sbjct: 727 LQCLLLGKNSLMNLSPHVGELSNLTHLELIGNYLETLPPELEGCQSLKRNCLIVEENLLN 786
Query: 371 EIPYGMSE 348
+P ++E
Sbjct: 787 TLPLPVTE 794
Score = 47.2 bits (107), Expect = 6e-05
Identities = 33/118 (27%), Positives = 52/118 (44%)
Frame = -2
Query: 716 IPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEV 537
IP + +L + L L L N + LP L L L+L N L +PE + L L+
Sbjct: 648 IPAQIGALSN-LEQLSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQY 706
Query: 536 LNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIP 363
++NN ++ LP L L+ + N L + L +L L+L N + +P
Sbjct: 707 FAVTNNNIEMLPDGLFQCKKLQCLLLGKNSLMNLSPHVGELSNLTHLELIGNYLETLP 764
Score = 45.6 bits (103), Expect = 2e-04
Identities = 58/218 (26%), Positives = 104/218 (47%), Gaps = 15/218 (6%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSK--------LKHLKQLNLDSNKLQAL 573
++ +IP VF L + L+ L LS VLP+ LS LK+L+ L L S+ L +
Sbjct: 498 EMGKIPRWVFHLKN-LKELYLSG---CVLPEQLSTMQLEGFQDLKNLRTLYLKSS-LSRI 552
Query: 572 PESLINL-KKLEVLNISNNFVQTLPVC-LKNLNNLKQVYASNNKLQAFPKQILGLQSLDV 399
P+ + +L L+ L++ N + + + LK + NLK + + L+ P I L +L
Sbjct: 553 PQVVTDLLPSLQKLSLDNEGSKLVVLNNLKKMVNLKSLELISCDLERIPHSIFSLNNLHE 612
Query: 398 LDLSHNKITEIPYGMSELYVIELN---LSQNEISLIGEDLHQAPRLKILRLDENCLSLDE 228
LDL N + + +S ++ L+ L N I+ I + L+ L LD N +++
Sbjct: 613 LDLRENNLKTVEEIISFQHLQNLSCLKLWHNNIAYIPAQIGALSNLEQLSLDHN--NIEN 670
Query: 227 IKPSLLRDSKIHTVSVDGN--LFEPKQLAXLEGYNEYS 120
+ L +K+H + + N F P+++ L ++
Sbjct: 671 LPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQYFA 708
Score = 31.9 bits (69), Expect = 2.5
Identities = 30/132 (22%), Positives = 58/132 (43%), Gaps = 7/132 (5%)
Frame = -2
Query: 584 LQALPESLINLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQA-FPKQILGLQS 408
L LP+++ L ++EVL++ LP + L NLK++ ++ L P ++
Sbjct: 429 LNGLPDNVFELTEMEVLSLELIPEVKLPSAVSQLVNLKELRVYHSSLVVDHPALAFLEEN 488
Query: 407 LDVLDLSHNKITEIP------YGMSELYVIELNLSQNEISLIGEDLHQAPRLKILRLDEN 246
L +L L ++ +IP + ELY+ L + ++ E L+ L L +
Sbjct: 489 LKILRLKFTEMGKIPRWVFHLKNLKELYLSGCVLPEQLSTMQLEGFQDLKNLRTLYLKSS 548
Query: 245 CLSLDEIKPSLL 210
+ ++ LL
Sbjct: 549 LSRIPQVVTDLL 560
>X72913-1|CAA51418.1| 376|Homo sapiens fibromodulin protein.
Length = 376
Score = 72.9 bits (171), Expect = 1e-12
Identities = 45/155 (29%), Positives = 84/155 (54%), Gaps = 2/155 (1%)
Frame = -2
Query: 629 SKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTLPV-CLKNLNNLKQVYASN 453
SKL+HL++L LD N L +P L + L L++ +N + +P L+ L NL +Y +
Sbjct: 152 SKLRHLERLYLDHNNLTRMPGPLP--RSLRELHLDHNQISRVPNNALEGLENLTALYLQH 209
Query: 452 NKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVIELNLSQNEISLIGEDLHQ-AP 276
N++Q + GL+SL +LDLS+N + ++P G+ + +L + N + + + + AP
Sbjct: 210 NEIQEVGSSMRGLRSLYLLDLSYNHLRKVPDGLPSA-LEQLYMEHNNVYTVPDSYFRGAP 268
Query: 275 RLKILRLDENCLSLDEIKPSLLRDSKIHTVSVDGN 171
+L +RL N L+ + + + S + + + N
Sbjct: 269 KLLYVRLSHNSLTNNGLASNTFNSSSLLELDLSYN 303
Score = 44.4 bits (100), Expect = 4e-04
Identities = 44/169 (26%), Positives = 78/169 (46%), Gaps = 8/169 (4%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
++ +P + + L L L N++ + + L+ L L+L N L+ +P+ L +
Sbjct: 187 QISRVPNNALEGLENLTALYLQHNEIQEVGSSMRGLRSLYLLDLSYNHLRKVPDGLPSA- 245
Query: 548 KLEVLNISNNFVQTLPVC-LKNLNNLKQVYASNNKL--QAFPKQILGLQSLDVLDLSHNK 378
LE L + +N V T+P + L V S+N L SL LDLS+N+
Sbjct: 246 -LEQLYMEHNNVYTVPDSYFRGAPKLLYVRLSHNSLTNNGLASNTFNSSSLLELDLSYNQ 304
Query: 377 ITEIP---YGMSELYVIELNLSQNEISLIGE--DLHQAPRLKILRLDEN 246
+ +IP + LY+ +++ IS D+ +L+++RLD N
Sbjct: 305 LQKIPPVNTNLENLYLQGNRINEFSISSFCTVVDVVNFSQLQVVRLDGN 353
>BC035281-1|AAH35281.1| 376|Homo sapiens fibromodulin protein.
Length = 376
Score = 72.9 bits (171), Expect = 1e-12
Identities = 45/155 (29%), Positives = 84/155 (54%), Gaps = 2/155 (1%)
Frame = -2
Query: 629 SKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTLPV-CLKNLNNLKQVYASN 453
SKL+HL++L LD N L +P L + L L++ +N + +P L+ L NL +Y +
Sbjct: 152 SKLRHLERLYLDHNNLTRMPGPLP--RSLRELHLDHNQISRVPNNALEGLENLTALYLQH 209
Query: 452 NKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVIELNLSQNEISLIGEDLHQ-AP 276
N++Q + GL+SL +LDLS+N + ++P G+ + +L + N + + + + AP
Sbjct: 210 NEIQEVGSSMRGLRSLILLDLSYNHLRKVPDGLPSA-LEQLYMEHNNVYTVPDSYFRGAP 268
Query: 275 RLKILRLDENCLSLDEIKPSLLRDSKIHTVSVDGN 171
+L +RL N L+ + + + S + + + N
Sbjct: 269 KLLYVRLSHNSLTNNGLASNTFNSSSLLELDLSYN 303
Score = 45.6 bits (103), Expect = 2e-04
Identities = 45/169 (26%), Positives = 78/169 (46%), Gaps = 8/169 (4%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
++ +P + + L L L N++ + + L+ L L+L N L+ +P+ L +
Sbjct: 187 QISRVPNNALEGLENLTALYLQHNEIQEVGSSMRGLRSLILLDLSYNHLRKVPDGLPSA- 245
Query: 548 KLEVLNISNNFVQTLPVC-LKNLNNLKQVYASNNKL--QAFPKQILGLQSLDVLDLSHNK 378
LE L + +N V T+P + L V S+N L SL LDLS+N+
Sbjct: 246 -LEQLYMEHNNVYTVPDSYFRGAPKLLYVRLSHNSLTNNGLASNTFNSSSLLELDLSYNQ 304
Query: 377 ITEIP---YGMSELYVIELNLSQNEISLIGE--DLHQAPRLKILRLDEN 246
+ +IP + LY+ +++ IS D+ +L++LRLD N
Sbjct: 305 LQKIPPVNTNLENLYLQGNRINEFSISSFCTVVDVVNFSKLQVLRLDGN 353
>AL359837-1|CAH73821.1| 376|Homo sapiens fibromodulin protein.
Length = 376
Score = 72.9 bits (171), Expect = 1e-12
Identities = 45/155 (29%), Positives = 84/155 (54%), Gaps = 2/155 (1%)
Frame = -2
Query: 629 SKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTLPV-CLKNLNNLKQVYASN 453
SKL+HL++L LD N L +P L + L L++ +N + +P L+ L NL +Y +
Sbjct: 152 SKLRHLERLYLDHNNLTRMPGPLP--RSLRELHLDHNQISRVPNNALEGLENLTALYLQH 209
Query: 452 NKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVIELNLSQNEISLIGEDLHQ-AP 276
N++Q + GL+SL +LDLS+N + ++P G+ + +L + N + + + + AP
Sbjct: 210 NEIQEVGSSMRGLRSLILLDLSYNHLRKVPDGLPSA-LEQLYMEHNNVYTVPDSYFRGAP 268
Query: 275 RLKILRLDENCLSLDEIKPSLLRDSKIHTVSVDGN 171
+L +RL N L+ + + + S + + + N
Sbjct: 269 KLLYVRLSHNSLTNNGLASNTFNSSSLLELDLSYN 303
Score = 45.6 bits (103), Expect = 2e-04
Identities = 45/169 (26%), Positives = 78/169 (46%), Gaps = 8/169 (4%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
++ +P + + L L L N++ + + L+ L L+L N L+ +P+ L +
Sbjct: 187 QISRVPNNALEGLENLTALYLQHNEIQEVGSSMRGLRSLILLDLSYNHLRKVPDGLPSA- 245
Query: 548 KLEVLNISNNFVQTLPVC-LKNLNNLKQVYASNNKL--QAFPKQILGLQSLDVLDLSHNK 378
LE L + +N V T+P + L V S+N L SL LDLS+N+
Sbjct: 246 -LEQLYMEHNNVYTVPDSYFRGAPKLLYVRLSHNSLTNNGLASNTFNSSSLLELDLSYNQ 304
Query: 377 ITEIP---YGMSELYVIELNLSQNEISLIGE--DLHQAPRLKILRLDEN 246
+ +IP + LY+ +++ IS D+ +L++LRLD N
Sbjct: 305 LQKIPPVNTNLENLYLQGNRINEFSISSFCTVVDVVNFSKLQVLRLDGN 353
>AL513211-2|CAI17359.1| 154|Homo sapiens leucine rich repeat
containing 1 protein.
Length = 154
Score = 71.3 bits (167), Expect = 3e-12
Identities = 42/128 (32%), Positives = 71/128 (55%), Gaps = 1/128 (0%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKL-KHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQT 507
+ ++D L +P+++ + + L++L LD+N+L+ LPE L KL L +S+N +Q
Sbjct: 14 VESIDKRHCSLVYVPEEIYRYARSLEELLLDANQLRELPEQFFQLVKLRKLGLSDNEIQR 73
Query: 506 LPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVIELN 327
LP + N L ++ S N++ P+ I ++L V D S N +T +P EL +
Sbjct: 74 LPPEIANFMQLVELDVSRNEIPEIPESISFCKALQVADFSGNPLTRLPESFPELQNLTC- 132
Query: 326 LSQNEISL 303
LS N+ISL
Sbjct: 133 LSVNDISL 140
Score = 62.5 bits (145), Expect = 2e-09
Identities = 34/123 (27%), Positives = 59/123 (47%)
Frame = -2
Query: 731 CKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINL 552
C L +P +++ L L L N+L LP+ +L L++L L N++Q LP + N
Sbjct: 22 CSLVYVPEEIYRYARSLEELLLDANQLRELPEQFFQLVKLRKLGLSDNEIQRLPPEIANF 81
Query: 551 KKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKIT 372
+L L++S N + +P + L+ S N L P+ LQ+L L ++ +
Sbjct: 82 MQLVELDVSRNEIPEIPESISFCKALQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQ 141
Query: 371 EIP 363
+P
Sbjct: 142 SLP 144
Score = 41.5 bits (93), Expect = 0.003
Identities = 28/91 (30%), Positives = 49/91 (53%), Gaps = 2/91 (2%)
Frame = -2
Query: 479 NLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSE-LYVIELNLSQNEISL 303
+L+++ N+L+ P+Q L L L LS N+I +P ++ + ++EL++S+NEI
Sbjct: 37 SLEELLLDANQLRELPEQFFQLVKLRKLGLSDNEIQRLPPEIANFMQLVELDVSRNEIPE 96
Query: 302 IGEDLHQAPRLKILRLDENCLS-LDEIKPSL 213
I E + L++ N L+ L E P L
Sbjct: 97 IPESISFCKALQVADFSGNPLTRLPESFPEL 127
Score = 39.1 bits (87), Expect = 0.016
Identities = 20/56 (35%), Positives = 35/56 (62%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESL 561
++ EIP + S C L+ D S N L+ LP+ +L++L L+++ LQ+LPE++
Sbjct: 93 EIPEIPESI-SFCKALQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLPENI 147
>X75546-1|CAA53233.1| 376|Homo sapiens fibromodulin protein.
Length = 376
Score = 70.9 bits (166), Expect = 4e-12
Identities = 44/155 (28%), Positives = 84/155 (54%), Gaps = 2/155 (1%)
Frame = -2
Query: 629 SKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTLPV-CLKNLNNLKQVYASN 453
SKL+HL++L LD N L +P L + L L++ +N + +P L+ L NL +Y +
Sbjct: 152 SKLRHLERLYLDHNNLTRMPGPLP--RSLRELHLDHNQISRVPNNALEGLENLTALYLQH 209
Query: 452 NKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVIELNLSQNEISLIGEDLHQ-AP 276
+++Q + GL+SL +LDLS+N + ++P G+ + +L + N + + + + AP
Sbjct: 210 DEIQEVGSSMRGLRSLILLDLSYNHLRKVPDGLPSA-LEQLYMEHNNVYTVPDSYFRGAP 268
Query: 275 RLKILRLDENCLSLDEIKPSLLRDSKIHTVSVDGN 171
+L +RL N L+ + + + S + + + N
Sbjct: 269 KLLYVRLSHNSLTNNGLASNTFNSSSLLELDLSYN 303
Score = 42.3 bits (95), Expect = 0.002
Identities = 43/169 (25%), Positives = 78/169 (46%), Gaps = 8/169 (4%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
++ +P + + L L L +++ + + L+ L L+L N L+ +P+ L +
Sbjct: 187 QISRVPNNALEGLENLTALYLQHDEIQEVGSSMRGLRSLILLDLSYNHLRKVPDGLPSA- 245
Query: 548 KLEVLNISNNFVQTLPVC-LKNLNNLKQVYASNNKL--QAFPKQILGLQSLDVLDLSHNK 378
LE L + +N V T+P + L V S+N L SL LDLS+N+
Sbjct: 246 -LEQLYMEHNNVYTVPDSYFRGAPKLLYVRLSHNSLTNNGLASNTFNSSSLLELDLSYNQ 304
Query: 377 ITEIP---YGMSELYVIELNLSQNEISLIGE--DLHQAPRLKILRLDEN 246
+ +IP + LY+ +++ IS D+ +L+++RLD N
Sbjct: 305 LQKIPPVNTNLENLYLQGNRINEFSISSFCTVVDVVNFSKLQVVRLDGN 353
>BC126277-1|AAI26278.1| 1205|Homo sapiens PH domain and leucine rich
repeat protein phosphatase protein.
Length = 1205
Score = 70.9 bits (166), Expect = 4e-12
Identities = 49/174 (28%), Positives = 92/174 (52%), Gaps = 10/174 (5%)
Frame = -2
Query: 731 CKLKEIPIDVFSLCDVLRNLDLSKNKLSVLP--------DDLSKLKHLKQLNLDSNKLQA 576
C L+ +P ++F D L +L+L +N L P ++L + LK LNL +N L
Sbjct: 135 CSLEHLPANLFYSQD-LTHLNLKQNFLRQNPSLPAARGLNELQRFTKLKSLNLSNNHLGD 193
Query: 575 LPESLINLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVL 396
P ++ ++ L LN+S N ++++P + ++NL+ N LQ+ P ++ ++ L L
Sbjct: 194 FPLAVCSIPTLAELNVSCNALRSVPAAVGVMHNLQTFLLDGNFLQSLPAELENMKQLSYL 253
Query: 395 DLSHNKITEIPYGMSELYVIE-LNLSQNEISLIG-EDLHQAPRLKILRLDENCL 240
LS N+ T+IP + +L ++ L +S N + + + L + P +K + L N +
Sbjct: 254 GLSFNEFTDIPEVLEKLTAVDKLCMSGNCVETLRLQALRKMPHIKHVDLRLNVI 307
Score = 60.1 bits (139), Expect = 8e-09
Identities = 36/107 (33%), Positives = 65/107 (60%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTL 504
L+ L S N+L L D +L +++ N+L+ +PE + +KLEVL+I +N + L
Sbjct: 362 LKALYASSNELVQL-DVYPVPNYLSYMDVSRNRLENVPEWVCESRKLEVLDIGHNQICEL 420
Query: 503 PVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIP 363
P L ++L+++ A +N+L P++ L S++VLD+ HN++ E+P
Sbjct: 421 PARLFCNSSLRKLLAGHNQLARLPER-LERTSVEVLDVQHNQLLELP 466
Score = 56.4 bits (130), Expect = 1e-07
Identities = 57/203 (28%), Positives = 101/203 (49%), Gaps = 22/203 (10%)
Frame = -2
Query: 683 LRNLDLSKNKL-SVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQT 507
++++DL N + ++ D++ L+H+ QL+L NKL L + N +EVL+ N + T
Sbjct: 297 IKHVDLRLNVIRKLIADEVDFLQHVTQLDLRDNKLGDLDAMIFN--NIEVLHCERNQLVT 354
Query: 506 LPVC---LKNL----NNLKQ--VY----------ASNNKLQAFPKQILGLQSLDVLDLSH 384
L +C LK L N L Q VY S N+L+ P+ + + L+VLD+ H
Sbjct: 355 LDICGYFLKALYASSNELVQLDVYPVPNYLSYMDVSRNRLENVPEWVCESRKLEVLDIGH 414
Query: 383 NKITEIPYGM-SELYVIELNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLL- 210
N+I E+P + + +L N+++ + E L + +++L + N L E+ P+LL
Sbjct: 415 NQICELPARLFCNSSLRKLLAGHNQLARLPERLERT-SVEVLDVQHN--QLLELPPNLLM 471
Query: 209 RDSKIHTVSVDGNLFEPKQLAXL 141
+ + ++ N E A L
Sbjct: 472 KADSLRFLNASANKLESLPPATL 494
Score = 56.0 bits (129), Expect = 1e-07
Identities = 50/167 (29%), Positives = 86/167 (51%), Gaps = 6/167 (3%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPD-DLSKLKH--LKQLNLDSNKL--QALPES 564
+L E+P ++ D LR L+ S NKL LP LS+ + L++L L +N L + +P
Sbjct: 461 QLLELPPNLLMKADSLRFLNASANKLESLPPATLSEETNSILQELYLTNNSLTDKCVP-L 519
Query: 563 LINLKKLEVLNISNNFVQTLPVC-LKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLS 387
L L++L+++ N +Q+ P + L L+++ S NKL+A P I+ + + +
Sbjct: 520 LTGHPHLKILHMAYNRLQSFPASKMAKLEELEEIDLSGNKLKAIPTTIMNCRRMHTVIAH 579
Query: 386 HNKITEIPYGMSELYVIELNLSQNEISLIGEDLHQAPRLKILRLDEN 246
N I P M + ++LS NE+S + + P+L+ L L N
Sbjct: 580 SNCIEVFPEVMQLPEIKCVDLSCNELSEVTLPENLPPKLQELDLTGN 626
Score = 52.4 bits (120), Expect = 2e-06
Identities = 43/157 (27%), Positives = 73/157 (46%), Gaps = 9/157 (5%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALP--------ESLINLKKLEVLNI 528
+ ++DLS L LP +L + L LNL N L+ P L KL+ LN+
Sbjct: 127 ISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLRQNPSLPAARGLNELQRFTKLKSLNL 186
Query: 527 SNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSE 348
SNN + P+ + ++ L ++ S N L++ P + + +L L N + +P +
Sbjct: 187 SNNHLGDFPLAVCSIPTLAELNVSCNALRSVPAAVGVMHNLQTFLLDGNFLQSLPAELEN 246
Query: 347 LYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDENCL 240
+ + L LS NE + I E L + + L + NC+
Sbjct: 247 MKQLSYLGLSFNEFTDIPEVLEKLTAVDKLCMSGNCV 283
Score = 49.2 bits (112), Expect = 2e-05
Identities = 49/188 (26%), Positives = 89/188 (47%), Gaps = 6/188 (3%)
Frame = -2
Query: 716 IPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEV 537
+ +DV+ + + L +D+S+N+L +P+ + + + L+ L++ N++ LP L L
Sbjct: 373 VQLDVYPVPNYLSYMDVSRNRLENVPEWVCESRKLEVLDIGHNQICELPARLFCNSSLRK 432
Query: 536 LNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYG 357
L +N + LP L+ + N L+ P ++ SL L+ S NK+ +P
Sbjct: 433 LLAGHNQLARLPERLERTSVEVLDVQHNQLLELPPNLLMKADSLRFLNASANKLESLPPA 492
Query: 356 -MSE---LYVIELNLSQNEIS-LIGEDLHQAPRLKILRLDENCL-SLDEIKPSLLRDSKI 195
+SE + EL L+ N ++ L P LKIL + N L S K + L + +
Sbjct: 493 TLSEETNSILQELYLTNNSLTDKCVPLLTGHPHLKILHMAYNRLQSFPASKMAKLEE--L 550
Query: 194 HTVSVDGN 171
+ + GN
Sbjct: 551 EEIDLSGN 558
Score = 46.8 bits (106), Expect = 8e-05
Identities = 40/169 (23%), Positives = 76/169 (44%), Gaps = 9/169 (5%)
Frame = -2
Query: 620 KHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQ---TLPVC-----LKNLNNLKQV 465
+ + ++L L+ LP +L + L LN+ NF++ +LP L+ LK +
Sbjct: 125 QRISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLRQNPSLPAARGLNELQRFTKLKSL 184
Query: 464 YASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVIE-LNLSQNEISLIGEDL 288
SNN L FP + + +L L++S N + +P + ++ ++ L N + + +L
Sbjct: 185 NLSNNHLGDFPLAVCSIPTLAELNVSCNALRSVPAAVGVMHNLQTFLLDGNFLQSLPAEL 244
Query: 287 HQAPRLKILRLDENCLSLDEIKPSLLRDSKIHTVSVDGNLFEPKQLAXL 141
+L L L N +I L + + + + + GN E +L L
Sbjct: 245 ENMKQLSYLGLSFN--EFTDIPEVLEKLTAVDKLCMSGNCVETLRLQAL 291
>BC057786-1|AAH57786.1| 512|Homo sapiens podocan-like 1 protein.
Length = 512
Score = 70.9 bits (166), Expect = 4e-12
Identities = 58/180 (32%), Positives = 90/180 (50%), Gaps = 9/180 (5%)
Frame = -2
Query: 683 LRNLDLSKNKLS---VLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFV 513
LR++ L N+LS + PD + + L+L +N+L LP SL LE L++ NN +
Sbjct: 171 LRSVYLHNNQLSNAGLPPDAFRGSEAIATLSLSNNQLSYLPPSLP--PSLERLHLQNNLI 228
Query: 512 QTLPV-CLKNLNNLKQVYASNNKLQAF---PKQILGLQSLDVLDLSHNKITEIPYGMSEL 345
+P L L+++Y +N+L L SL+ LDLSHN++T +P G+
Sbjct: 229 SKVPRGALSRQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYLDLSHNQLTTVPAGLPRT 288
Query: 344 YVIELNLSQNEISLI-GEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSK-IHTVSVDGN 171
I L+L +N I + LH A L+ L L N L + LR + +HT+ + GN
Sbjct: 289 LAI-LHLGRNRIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAGALRPLRGLHTLHLYGN 347
Score = 42.3 bits (95), Expect = 0.002
Identities = 48/163 (29%), Positives = 76/163 (46%), Gaps = 8/163 (4%)
Frame = -2
Query: 683 LRNLDLSKNKL--SVLPDD-LSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFV 513
LR L L N+L S LP L L+ L L+L N L +P +L ++L L + +N V
Sbjct: 313 LRYLLLQHNQLGSSGLPAGALRPLRGLHTLHLYGNGLDRVPPALP--RRLRALVLPHNHV 370
Query: 512 QTLP----VCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSEL 345
L V L L Y + + L++L LDL+ N++T +P G+
Sbjct: 371 AALGARDLVATPGLTELNLAYNRLASARVHHRAFRRLRALRSLDLAGNQLTRLPMGL-PT 429
Query: 344 YVIELNLSQNEISLI-GEDLHQAPRLKILRLDENCLSLDEIKP 219
+ L L +N++ ++ E L +L+ L L N L + +I P
Sbjct: 430 GLRTLQLQRNQLRMLEPEPLAGLDQLRELSLAHNRLRVGDIGP 472
>BC052279-1|AAH52279.1| 307|Homo sapiens leucine rich repeat
containing 59 protein.
Length = 307
Score = 70.9 bits (166), Expect = 4e-12
Identities = 40/103 (38%), Positives = 54/103 (52%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKK 546
L E+P+ + LDLS NKL+ LP D L HL +L+L NKLQ LP L
Sbjct: 27 LNEVPVKELAALPKATILDLSCNKLTTLPSDFCGLTHLVKLDLSKNKLQQLPADFGRLVN 86
Query: 545 LEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILG 417
L+ L++ NN + TLPV L NLK + +N L ++ G
Sbjct: 87 LQHLDLLNNKLVTLPVSFAQLKNLKWLDLKDNPLDPVLAKVAG 129
Score = 57.2 bits (132), Expect = 6e-08
Identities = 37/104 (35%), Positives = 52/104 (50%), Gaps = 1/104 (0%)
Frame = -2
Query: 674 LDLSKNKLSVLP-DDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTLPV 498
LDLS + L+ +P +L+ L L+L NKL LP L L L++S N +Q LP
Sbjct: 20 LDLSLSDLNEVPVKELAALPKATILDLSCNKLTTLPSDFCGLTHLVKLDLSKNKLQQLPA 79
Query: 497 CLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEI 366
L NL+ + NNKL P L++L LDL N + +
Sbjct: 80 DFGRLVNLQHLDLLNNKLVTLPVSFAQLKNLKWLDLKDNPLDPV 123
Score = 50.0 bits (114), Expect = 9e-06
Identities = 33/102 (32%), Positives = 55/102 (53%), Gaps = 2/102 (1%)
Frame = -2
Query: 608 QLNLDSNKLQALP-ESLINLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFP 432
+L+L + L +P + L L K +L++S N + TLP L +L ++ S NKLQ P
Sbjct: 19 ELDLSLSDLNEVPVKELAALPKATILDLSCNKLTTLPSDFCGLTHLVKLDLSKNKLQQLP 78
Query: 431 KQILGLQSLDVLDLSHNKITEIPYGMSELYVIE-LNLSQNEI 309
L +L LDL +NK+ +P ++L ++ L+L N +
Sbjct: 79 ADFGRLVNLQHLDLLNNKLVTLPVSFAQLKNLKWLDLKDNPL 120
>BC017168-1|AAH17168.1| 307|Homo sapiens leucine rich repeat
containing 59 protein.
Length = 307
Score = 70.9 bits (166), Expect = 4e-12
Identities = 40/103 (38%), Positives = 54/103 (52%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKK 546
L E+P+ + LDLS NKL+ LP D L HL +L+L NKLQ LP L
Sbjct: 27 LNEVPVKELAALPKATILDLSCNKLTTLPSDFCGLTHLVKLDLSKNKLQQLPADFGRLVN 86
Query: 545 LEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILG 417
L+ L++ NN + TLPV L NLK + +N L ++ G
Sbjct: 87 LQHLDLLNNKLVTLPVSFAQLKNLKWLDLKDNPLDPVLAKVAG 129
Score = 57.2 bits (132), Expect = 6e-08
Identities = 37/104 (35%), Positives = 52/104 (50%), Gaps = 1/104 (0%)
Frame = -2
Query: 674 LDLSKNKLSVLP-DDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTLPV 498
LDLS + L+ +P +L+ L L+L NKL LP L L L++S N +Q LP
Sbjct: 20 LDLSLSDLNEVPVKELAALPKATILDLSCNKLTTLPSDFCGLTHLVKLDLSKNKLQQLPA 79
Query: 497 CLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEI 366
L NL+ + NNKL P L++L LDL N + +
Sbjct: 80 DFGRLVNLQHLDLLNNKLVTLPVSFAQLKNLKWLDLKDNPLDPV 123
Score = 50.0 bits (114), Expect = 9e-06
Identities = 33/102 (32%), Positives = 55/102 (53%), Gaps = 2/102 (1%)
Frame = -2
Query: 608 QLNLDSNKLQALP-ESLINLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFP 432
+L+L + L +P + L L K +L++S N + TLP L +L ++ S NKLQ P
Sbjct: 19 ELDLSLSDLNEVPVKELAALPKATILDLSCNKLTTLPSDFCGLTHLVKLDLSKNKLQQLP 78
Query: 431 KQILGLQSLDVLDLSHNKITEIPYGMSELYVIE-LNLSQNEI 309
L +L LDL +NK+ +P ++L ++ L+L N +
Sbjct: 79 ADFGRLVNLQHLDLLNNKLVTLPVSFAQLKNLKWLDLKDNPL 120
>BC014927-1|AAH14927.3| 1205|Homo sapiens PH domain and leucine rich
repeat protein phosphatase protein.
Length = 1205
Score = 70.9 bits (166), Expect = 4e-12
Identities = 49/174 (28%), Positives = 92/174 (52%), Gaps = 10/174 (5%)
Frame = -2
Query: 731 CKLKEIPIDVFSLCDVLRNLDLSKNKLSVLP--------DDLSKLKHLKQLNLDSNKLQA 576
C L+ +P ++F D L +L+L +N L P ++L + LK LNL +N L
Sbjct: 135 CSLEHLPANLFYSQD-LTHLNLKQNFLRQNPSLPAARGLNELQRFTKLKSLNLSNNHLGD 193
Query: 575 LPESLINLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVL 396
P ++ ++ L LN+S N ++++P + ++NL+ N LQ+ P ++ ++ L L
Sbjct: 194 FPLAVCSIPTLAELNVSCNALRSVPAAVGVMHNLQTFLLDGNFLQSLPAELENMKQLSYL 253
Query: 395 DLSHNKITEIPYGMSELYVIE-LNLSQNEISLIG-EDLHQAPRLKILRLDENCL 240
LS N+ T+IP + +L ++ L +S N + + + L + P +K + L N +
Sbjct: 254 GLSFNEFTDIPEVLEKLTAVDKLCMSGNCVETLRLQALRKMPHIKHVDLRLNVI 307
Score = 60.1 bits (139), Expect = 8e-09
Identities = 36/107 (33%), Positives = 65/107 (60%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTL 504
L+ L S N+L L D +L +++ N+L+ +PE + +KLEVL+I +N + L
Sbjct: 362 LKALYASSNELVQL-DVYPVPNYLSYMDVSRNRLENVPEWVCESRKLEVLDIGHNQICEL 420
Query: 503 PVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIP 363
P L ++L+++ A +N+L P++ L S++VLD+ HN++ E+P
Sbjct: 421 PARLFCNSSLRKLLAGHNQLARLPER-LERTSVEVLDVQHNQLLELP 466
Score = 56.4 bits (130), Expect = 1e-07
Identities = 57/203 (28%), Positives = 101/203 (49%), Gaps = 22/203 (10%)
Frame = -2
Query: 683 LRNLDLSKNKL-SVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQT 507
++++DL N + ++ D++ L+H+ QL+L NKL L + N +EVL+ N + T
Sbjct: 297 IKHVDLRLNVIRKLIADEVDFLQHVTQLDLRDNKLGDLDAMIFN--NIEVLHCERNQLVT 354
Query: 506 LPVC---LKNL----NNLKQ--VY----------ASNNKLQAFPKQILGLQSLDVLDLSH 384
L +C LK L N L Q VY S N+L+ P+ + + L+VLD+ H
Sbjct: 355 LDICGYFLKALYASSNELVQLDVYPVPNYLSYMDVSRNRLENVPEWVCESRKLEVLDIGH 414
Query: 383 NKITEIPYGM-SELYVIELNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLL- 210
N+I E+P + + +L N+++ + E L + +++L + N L E+ P+LL
Sbjct: 415 NQICELPARLFCNSSLRKLLAGHNQLARLPERLERT-SVEVLDVQHN--QLLELPPNLLM 471
Query: 209 RDSKIHTVSVDGNLFEPKQLAXL 141
+ + ++ N E A L
Sbjct: 472 KADSLRFLNASANKLESLPPATL 494
Score = 56.0 bits (129), Expect = 1e-07
Identities = 50/167 (29%), Positives = 86/167 (51%), Gaps = 6/167 (3%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPD-DLSKLKH--LKQLNLDSNKL--QALPES 564
+L E+P ++ D LR L+ S NKL LP LS+ + L++L L +N L + +P
Sbjct: 461 QLLELPPNLLMKADSLRFLNASANKLESLPPATLSEETNSILQELYLTNNSLTDKCVP-L 519
Query: 563 LINLKKLEVLNISNNFVQTLPVC-LKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLS 387
L L++L+++ N +Q+ P + L L+++ S NKL+A P I+ + + +
Sbjct: 520 LTGHPHLKILHMAYNRLQSFPASKMAKLEELEEIDLSGNKLKAIPTTIMNCRRMHTVIAH 579
Query: 386 HNKITEIPYGMSELYVIELNLSQNEISLIGEDLHQAPRLKILRLDEN 246
N I P M + ++LS NE+S + + P+L+ L L N
Sbjct: 580 SNCIEVFPEVMQLPEIKCVDLSCNELSEVTLPENLPPKLQELDLTGN 626
Score = 52.4 bits (120), Expect = 2e-06
Identities = 43/157 (27%), Positives = 73/157 (46%), Gaps = 9/157 (5%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALP--------ESLINLKKLEVLNI 528
+ ++DLS L LP +L + L LNL N L+ P L KL+ LN+
Sbjct: 127 ISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLRQNPSLPAARGLNELQRFTKLKSLNL 186
Query: 527 SNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSE 348
SNN + P+ + ++ L ++ S N L++ P + + +L L N + +P +
Sbjct: 187 SNNHLGDFPLAVCSIPTLAELNVSCNALRSVPAAVGVMHNLQTFLLDGNFLQSLPAELEN 246
Query: 347 LYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDENCL 240
+ + L LS NE + I E L + + L + NC+
Sbjct: 247 MKQLSYLGLSFNEFTDIPEVLEKLTAVDKLCMSGNCV 283
Score = 49.2 bits (112), Expect = 2e-05
Identities = 49/188 (26%), Positives = 89/188 (47%), Gaps = 6/188 (3%)
Frame = -2
Query: 716 IPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEV 537
+ +DV+ + + L +D+S+N+L +P+ + + + L+ L++ N++ LP L L
Sbjct: 373 VQLDVYPVPNYLSYMDVSRNRLENVPEWVCESRKLEVLDIGHNQICELPARLFCNSSLRK 432
Query: 536 LNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYG 357
L +N + LP L+ + N L+ P ++ SL L+ S NK+ +P
Sbjct: 433 LLAGHNQLARLPERLERTSVEVLDVQHNQLLELPPNLLMKADSLRFLNASANKLESLPPA 492
Query: 356 -MSE---LYVIELNLSQNEIS-LIGEDLHQAPRLKILRLDENCL-SLDEIKPSLLRDSKI 195
+SE + EL L+ N ++ L P LKIL + N L S K + L + +
Sbjct: 493 TLSEETNSILQELYLTNNSLTDKCVPLLTGHPHLKILHMAYNRLQSFPASKMAKLEE--L 550
Query: 194 HTVSVDGN 171
+ + GN
Sbjct: 551 EEIDLSGN 558
Score = 46.8 bits (106), Expect = 8e-05
Identities = 40/169 (23%), Positives = 76/169 (44%), Gaps = 9/169 (5%)
Frame = -2
Query: 620 KHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQ---TLPVC-----LKNLNNLKQV 465
+ + ++L L+ LP +L + L LN+ NF++ +LP L+ LK +
Sbjct: 125 QRISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLRQNPSLPAARGLNELQRFTKLKSL 184
Query: 464 YASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVIE-LNLSQNEISLIGEDL 288
SNN L FP + + +L L++S N + +P + ++ ++ L N + + +L
Sbjct: 185 NLSNNHLGDFPLAVCSIPTLAELNVSCNALRSVPAAVGVMHNLQTFLLDGNFLQSLPAEL 244
Query: 287 HQAPRLKILRLDENCLSLDEIKPSLLRDSKIHTVSVDGNLFEPKQLAXL 141
+L L L N +I L + + + + + GN E +L L
Sbjct: 245 ENMKQLSYLGLSFN--EFTDIPEVLEKLTAVDKLCMSGNCVETLRLQAL 291
>AL365215-2|CAH73632.1| 224|Homo sapiens Ras suppressor protein 1
protein.
Length = 224
Score = 70.9 bits (166), Expect = 4e-12
Identities = 44/135 (32%), Positives = 72/135 (53%), Gaps = 3/135 (2%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNIS-NNFVQ- 510
L L+ N++ LP +S L+ LK LNL N+L LP +L LEVL+++ NN +
Sbjct: 12 LEVLNFFNNQIEELPTQISSLQKLKHLNLGMNRLNTLPRGFGSLPALEVLDLTYNNLSEN 71
Query: 509 TLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVI-E 333
+LP L L+ +Y S+N + P I L L +L L N + +P + EL + E
Sbjct: 72 SLPGNFFYLTTLRALYLSDNDFEILPPDIGKLTKLQILSLRDNDLISLPKEIGELTQLKE 131
Query: 332 LNLSQNEISLIGEDL 288
L++ N ++++ +L
Sbjct: 132 LHIQGNRLTVLPPEL 146
Score = 70.5 bits (165), Expect = 6e-12
Identities = 47/152 (30%), Positives = 81/152 (53%), Gaps = 6/152 (3%)
Frame = -2
Query: 575 LPESLINLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVL 396
+P ++ LK LEVLN NN ++ LP + +L LK + N+L P+ L +L+VL
Sbjct: 2 VPPNIAELKNLEVLNFFNNQIEELPTQISSLQKLKHLNLGMNRLNTLPRGFGSLPALEVL 61
Query: 395 DLSHNKITE--IPYGMSELYVIE-LNLSQNEISLIGEDLHQAPRLKILRL-DENCLSLDE 228
DL++N ++E +P L + L LS N+ ++ D+ + +L+IL L D + +SL +
Sbjct: 62 DLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGKLTKLQILSLRDNDLISLPK 121
Query: 227 IKPSLLRDSKIHTVSVDGNLFE--PKQLAXLE 138
L + ++H + GN P +L L+
Sbjct: 122 EIGELTQLKELH---IQGNRLTVLPPELGNLD 150
Score = 60.9 bits (141), Expect = 5e-09
Identities = 39/141 (27%), Positives = 80/141 (56%), Gaps = 3/141 (2%)
Frame = -2
Query: 647 VLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTLPVCLKNLNNLKQ 468
++P ++++LK+L+ LN +N+++ LP + +L+KL+ LN+ N + TLP +L L+
Sbjct: 1 MVPPNIAELKNLEVLNFFNNQIEELPTQISSLQKLKHLNLGMNRLNTLPRGFGSLPALEV 60
Query: 467 VYASNNKL--QAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVIE-LNLSQNEISLIG 297
+ + N L + P L +L L LS N +P + +L ++ L+L N++ +
Sbjct: 61 LDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGKLTKLQILSLRDNDLISLP 120
Query: 296 EDLHQAPRLKILRLDENCLSL 234
+++ + +LK L + N L++
Sbjct: 121 KEIGELTQLKELHIQGNRLTV 141
Score = 52.4 bits (120), Expect = 2e-06
Identities = 33/86 (38%), Positives = 47/86 (54%), Gaps = 2/86 (2%)
Frame = -2
Query: 701 FSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISN 522
F LR L LS N +LP D+ KL L+ L+L N L +LP+ + L +L+ L+I
Sbjct: 77 FFYLTTLRALYLSDNDFEILPPDIGKLTKLQILSLRDNDLISLPKEIGELTQLKELHIQG 136
Query: 521 NFVQTLPVCLKNLN--NLKQVYASNN 450
N + LP L NL+ KQV+ + N
Sbjct: 137 NRLTVLPPELGNLDLTGQKQVFKAEN 162
Score = 51.2 bits (117), Expect = 4e-06
Identities = 30/95 (31%), Positives = 49/95 (51%), Gaps = 2/95 (2%)
Frame = -2
Query: 701 FSLCDVLRNLDLSKNKLSV--LPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNI 528
F L LDL+ N LS LP + L L+ L L N + LP + L KL++L++
Sbjct: 52 FGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGKLTKLQILSL 111
Query: 527 SNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQI 423
+N + +LP + L LK+++ N+L P ++
Sbjct: 112 RDNDLISLPKEIGELTQLKELHIQGNRLTVLPPEL 146
>AK001924-1|BAA91980.1| 721|Homo sapiens protein ( Homo sapiens
cDNA FLJ11062 fis, clone PLACE1004804, weakly similar to
ADENYLATE CYCLASE (EC 4.6.1.1). ).
Length = 721
Score = 70.9 bits (166), Expect = 4e-12
Identities = 49/174 (28%), Positives = 92/174 (52%), Gaps = 10/174 (5%)
Frame = -2
Query: 731 CKLKEIPIDVFSLCDVLRNLDLSKNKLSVLP--------DDLSKLKHLKQLNLDSNKLQA 576
C L+ +P ++F D L +L+L +N L P ++L + LK LNL +N L
Sbjct: 135 CSLEHLPANLFYSQD-LTHLNLKQNFLRQNPSLPAARGLNELQRFAKLKSLNLSNNHLGD 193
Query: 575 LPESLINLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVL 396
P ++ ++ L LN+S N ++++P + ++NL+ N LQ+ P ++ ++ L L
Sbjct: 194 FPLAVCSIPTLAELNVSCNALRSVPAAVGVMHNLQTFLLDGNFLQSLPAELENMKQLSYL 253
Query: 395 DLSHNKITEIPYGMSELYVIE-LNLSQNEISLIG-EDLHQAPRLKILRLDENCL 240
LS N+ T+IP + +L ++ L +S N + + + L + P +K + L N +
Sbjct: 254 GLSFNEFTDIPEVLEKLTAVDKLCMSGNCVETLRLQALRKMPHIKHVDLRLNVI 307
Score = 60.1 bits (139), Expect = 8e-09
Identities = 36/107 (33%), Positives = 65/107 (60%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTL 504
L+ L S N+L L D +L +++ N+L+ +PE + +KLEVL+I +N + L
Sbjct: 362 LKALYASSNELVQL-DVYPVPNYLSYMDVSRNRLENVPEWVCESRKLEVLDIGHNQICEL 420
Query: 503 PVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIP 363
P L ++L+++ A +N+L P++ L S++VLD+ HN++ E+P
Sbjct: 421 PARLFCNSSLRKLLAGHNQLARLPER-LERTSVEVLDVQHNQLLELP 466
Score = 56.4 bits (130), Expect = 1e-07
Identities = 57/203 (28%), Positives = 101/203 (49%), Gaps = 22/203 (10%)
Frame = -2
Query: 683 LRNLDLSKNKL-SVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQT 507
++++DL N + ++ D++ L+H+ QL+L NKL L + N +EVL+ N + T
Sbjct: 297 IKHVDLRLNVIRKLIADEVDFLQHVTQLDLRDNKLGDLDAMIFN--NIEVLHCERNQLVT 354
Query: 506 LPVC---LKNL----NNLKQ--VY----------ASNNKLQAFPKQILGLQSLDVLDLSH 384
L +C LK L N L Q VY S N+L+ P+ + + L+VLD+ H
Sbjct: 355 LDICGYFLKALYASSNELVQLDVYPVPNYLSYMDVSRNRLENVPEWVCESRKLEVLDIGH 414
Query: 383 NKITEIPYGM-SELYVIELNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLL- 210
N+I E+P + + +L N+++ + E L + +++L + N L E+ P+LL
Sbjct: 415 NQICELPARLFCNSSLRKLLAGHNQLARLPERLERT-SVEVLDVQHN--QLLELPPNLLM 471
Query: 209 RDSKIHTVSVDGNLFEPKQLAXL 141
+ + ++ N E A L
Sbjct: 472 KADSLRFLNASANKLESLPPATL 494
Score = 56.0 bits (129), Expect = 1e-07
Identities = 50/167 (29%), Positives = 86/167 (51%), Gaps = 6/167 (3%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPD-DLSKLKH--LKQLNLDSNKL--QALPES 564
+L E+P ++ D LR L+ S NKL LP LS+ + L++L L +N L + +P
Sbjct: 461 QLLELPPNLLMKADSLRFLNASANKLESLPPATLSEETNSILQELYLTNNSLTDKCVP-L 519
Query: 563 LINLKKLEVLNISNNFVQTLPVC-LKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLS 387
L L++L+++ N +Q+ P + L L+++ S NKL+A P I+ + + +
Sbjct: 520 LTGHPHLKILHMAYNRLQSFPASKMAKLEELEEIDLSGNKLKAIPTTIMNCRRMHTVIAH 579
Query: 386 HNKITEIPYGMSELYVIELNLSQNEISLIGEDLHQAPRLKILRLDEN 246
N I P M + ++LS NE+S + + P+L+ L L N
Sbjct: 580 SNCIEVFPEVMQLPEIKCVDLSCNELSEVTLPENLPPKLQELDLTGN 626
Score = 52.4 bits (120), Expect = 2e-06
Identities = 43/157 (27%), Positives = 73/157 (46%), Gaps = 9/157 (5%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALP--------ESLINLKKLEVLNI 528
+ ++DLS L LP +L + L LNL N L+ P L KL+ LN+
Sbjct: 127 ISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLRQNPSLPAARGLNELQRFAKLKSLNL 186
Query: 527 SNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSE 348
SNN + P+ + ++ L ++ S N L++ P + + +L L N + +P +
Sbjct: 187 SNNHLGDFPLAVCSIPTLAELNVSCNALRSVPAAVGVMHNLQTFLLDGNFLQSLPAELEN 246
Query: 347 LYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDENCL 240
+ + L LS NE + I E L + + L + NC+
Sbjct: 247 MKQLSYLGLSFNEFTDIPEVLEKLTAVDKLCMSGNCV 283
Score = 49.2 bits (112), Expect = 2e-05
Identities = 49/188 (26%), Positives = 89/188 (47%), Gaps = 6/188 (3%)
Frame = -2
Query: 716 IPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEV 537
+ +DV+ + + L +D+S+N+L +P+ + + + L+ L++ N++ LP L L
Sbjct: 373 VQLDVYPVPNYLSYMDVSRNRLENVPEWVCESRKLEVLDIGHNQICELPARLFCNSSLRK 432
Query: 536 LNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYG 357
L +N + LP L+ + N L+ P ++ SL L+ S NK+ +P
Sbjct: 433 LLAGHNQLARLPERLERTSVEVLDVQHNQLLELPPNLLMKADSLRFLNASANKLESLPPA 492
Query: 356 -MSE---LYVIELNLSQNEIS-LIGEDLHQAPRLKILRLDENCL-SLDEIKPSLLRDSKI 195
+SE + EL L+ N ++ L P LKIL + N L S K + L + +
Sbjct: 493 TLSEETNSILQELYLTNNSLTDKCVPLLTGHPHLKILHMAYNRLQSFPASKMAKLEE--L 550
Query: 194 HTVSVDGN 171
+ + GN
Sbjct: 551 EEIDLSGN 558
Score = 46.0 bits (104), Expect = 1e-04
Identities = 40/169 (23%), Positives = 76/169 (44%), Gaps = 9/169 (5%)
Frame = -2
Query: 620 KHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQ---TLPVC-----LKNLNNLKQV 465
+ + ++L L+ LP +L + L LN+ NF++ +LP L+ LK +
Sbjct: 125 QRISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLRQNPSLPAARGLNELQRFAKLKSL 184
Query: 464 YASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVIE-LNLSQNEISLIGEDL 288
SNN L FP + + +L L++S N + +P + ++ ++ L N + + +L
Sbjct: 185 NLSNNHLGDFPLAVCSIPTLAELNVSCNALRSVPAAVGVMHNLQTFLLDGNFLQSLPAEL 244
Query: 287 HQAPRLKILRLDENCLSLDEIKPSLLRDSKIHTVSVDGNLFEPKQLAXL 141
+L L L N +I L + + + + + GN E +L L
Sbjct: 245 ENMKQLSYLGLSFN--EFTDIPEVLEKLTAVDKLCMSGNCVETLRLQAL 291
>AB011178-1|BAA25532.2| 1369|Homo sapiens KIAA0606 protein protein.
Length = 1369
Score = 70.9 bits (166), Expect = 4e-12
Identities = 49/174 (28%), Positives = 92/174 (52%), Gaps = 10/174 (5%)
Frame = -2
Query: 731 CKLKEIPIDVFSLCDVLRNLDLSKNKLSVLP--------DDLSKLKHLKQLNLDSNKLQA 576
C L+ +P ++F D L +L+L +N L P ++L + LK LNL +N L
Sbjct: 299 CSLEHLPANLFYSQD-LTHLNLKQNFLRQNPSLPAARGLNELQRFTKLKSLNLSNNHLGD 357
Query: 575 LPESLINLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVL 396
P ++ ++ L LN+S N ++++P + ++NL+ N LQ+ P ++ ++ L L
Sbjct: 358 FPLAVCSIPTLAELNVSCNALRSVPAAVGVMHNLQTFLLDGNFLQSLPAELENMKQLSYL 417
Query: 395 DLSHNKITEIPYGMSELYVIE-LNLSQNEISLIG-EDLHQAPRLKILRLDENCL 240
LS N+ T+IP + +L ++ L +S N + + + L + P +K + L N +
Sbjct: 418 GLSFNEFTDIPEVLEKLTAVDKLCMSGNCVETLRLQALRKMPHIKHVDLRLNVI 471
Score = 60.1 bits (139), Expect = 8e-09
Identities = 36/107 (33%), Positives = 65/107 (60%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTL 504
L+ L S N+L L D +L +++ N+L+ +PE + +KLEVL+I +N + L
Sbjct: 526 LKALYASSNELVQL-DVYPVPNYLSYMDVSRNRLENVPEWVCESRKLEVLDIGHNQICEL 584
Query: 503 PVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIP 363
P L ++L+++ A +N+L P++ L S++VLD+ HN++ E+P
Sbjct: 585 PARLFCNSSLRKLLAGHNQLARLPER-LERTSVEVLDVQHNQLLELP 630
Score = 56.4 bits (130), Expect = 1e-07
Identities = 57/203 (28%), Positives = 101/203 (49%), Gaps = 22/203 (10%)
Frame = -2
Query: 683 LRNLDLSKNKL-SVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQT 507
++++DL N + ++ D++ L+H+ QL+L NKL L + N +EVL+ N + T
Sbjct: 461 IKHVDLRLNVIRKLIADEVDFLQHVTQLDLRDNKLGDLDAMIFN--NIEVLHCERNQLVT 518
Query: 506 LPVC---LKNL----NNLKQ--VY----------ASNNKLQAFPKQILGLQSLDVLDLSH 384
L +C LK L N L Q VY S N+L+ P+ + + L+VLD+ H
Sbjct: 519 LDICGYFLKALYASSNELVQLDVYPVPNYLSYMDVSRNRLENVPEWVCESRKLEVLDIGH 578
Query: 383 NKITEIPYGM-SELYVIELNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLL- 210
N+I E+P + + +L N+++ + E L + +++L + N L E+ P+LL
Sbjct: 579 NQICELPARLFCNSSLRKLLAGHNQLARLPERLERT-SVEVLDVQHN--QLLELPPNLLM 635
Query: 209 RDSKIHTVSVDGNLFEPKQLAXL 141
+ + ++ N E A L
Sbjct: 636 KADSLRFLNASANKLESLPPATL 658
Score = 55.6 bits (128), Expect = 2e-07
Identities = 50/167 (29%), Positives = 85/167 (50%), Gaps = 6/167 (3%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPD-DLSKLKH--LKQLNLDSNKL--QALPES 564
+L E+P ++ D LR L+ S NKL LP LS+ + L++L L +N L + +P
Sbjct: 625 QLLELPPNLLMKADSLRFLNASANKLESLPPATLSEETNSILQELYLTNNSLTDKCVP-L 683
Query: 563 LINLKKLEVLNISNNFVQTLPVC-LKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLS 387
L L++L+++ N +Q+ P + L L+++ S NKL+A P I+ + +
Sbjct: 684 LTGHPHLKILHMAYNRLQSFPASKMAKLEELEEIDLSGNKLKAIPTTIMNCSRMHTVIAH 743
Query: 386 HNKITEIPYGMSELYVIELNLSQNEISLIGEDLHQAPRLKILRLDEN 246
N I P M + ++LS NE+S + + P+L+ L L N
Sbjct: 744 SNCIEVFPEVMQLPEIKCVDLSCNELSEVTLPENLPPKLQELDLTGN 790
Score = 52.4 bits (120), Expect = 2e-06
Identities = 43/157 (27%), Positives = 73/157 (46%), Gaps = 9/157 (5%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALP--------ESLINLKKLEVLNI 528
+ ++DLS L LP +L + L LNL N L+ P L KL+ LN+
Sbjct: 291 ISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLRQNPSLPAARGLNELQRFTKLKSLNL 350
Query: 527 SNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSE 348
SNN + P+ + ++ L ++ S N L++ P + + +L L N + +P +
Sbjct: 351 SNNHLGDFPLAVCSIPTLAELNVSCNALRSVPAAVGVMHNLQTFLLDGNFLQSLPAELEN 410
Query: 347 LYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDENCL 240
+ + L LS NE + I E L + + L + NC+
Sbjct: 411 MKQLSYLGLSFNEFTDIPEVLEKLTAVDKLCMSGNCV 447
Score = 49.2 bits (112), Expect = 2e-05
Identities = 49/188 (26%), Positives = 89/188 (47%), Gaps = 6/188 (3%)
Frame = -2
Query: 716 IPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEV 537
+ +DV+ + + L +D+S+N+L +P+ + + + L+ L++ N++ LP L L
Sbjct: 537 VQLDVYPVPNYLSYMDVSRNRLENVPEWVCESRKLEVLDIGHNQICELPARLFCNSSLRK 596
Query: 536 LNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYG 357
L +N + LP L+ + N L+ P ++ SL L+ S NK+ +P
Sbjct: 597 LLAGHNQLARLPERLERTSVEVLDVQHNQLLELPPNLLMKADSLRFLNASANKLESLPPA 656
Query: 356 -MSE---LYVIELNLSQNEIS-LIGEDLHQAPRLKILRLDENCL-SLDEIKPSLLRDSKI 195
+SE + EL L+ N ++ L P LKIL + N L S K + L + +
Sbjct: 657 TLSEETNSILQELYLTNNSLTDKCVPLLTGHPHLKILHMAYNRLQSFPASKMAKLEE--L 714
Query: 194 HTVSVDGN 171
+ + GN
Sbjct: 715 EEIDLSGN 722
Score = 46.8 bits (106), Expect = 8e-05
Identities = 40/169 (23%), Positives = 76/169 (44%), Gaps = 9/169 (5%)
Frame = -2
Query: 620 KHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQ---TLPVC-----LKNLNNLKQV 465
+ + ++L L+ LP +L + L LN+ NF++ +LP L+ LK +
Sbjct: 289 QRISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLRQNPSLPAARGLNELQRFTKLKSL 348
Query: 464 YASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVIE-LNLSQNEISLIGEDL 288
SNN L FP + + +L L++S N + +P + ++ ++ L N + + +L
Sbjct: 349 NLSNNHLGDFPLAVCSIPTLAELNVSCNALRSVPAAVGVMHNLQTFLLDGNFLQSLPAEL 408
Query: 287 HQAPRLKILRLDENCLSLDEIKPSLLRDSKIHTVSVDGNLFEPKQLAXL 141
+L L L N +I L + + + + + GN E +L L
Sbjct: 409 ENMKQLSYLGLSFN--EFTDIPEVLEKLTAVDKLCMSGNCVETLRLQAL 455
>BC113973-1|AAI13974.1| 803|Homo sapiens factor for adipocyte
differentiation 158 protein.
Length = 803
Score = 70.1 bits (164), Expect = 8e-12
Identities = 57/187 (30%), Positives = 91/187 (48%), Gaps = 6/187 (3%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLS--KLKHLKQLNLDSNKLQALPE 567
+ C L+ IP VFSL L+ LDL +N L + + +S L+ L L L N + +PE
Sbjct: 596 LVHCDLERIPHAVFSLLS-LQELDLKENNLKSIEEIVSFQHLRKLTVLKLWHNSITYIPE 654
Query: 566 SLINLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLS 387
+ L LE L+ S+N ++ LP L N ++ + S N ++ P +I LQSL ++
Sbjct: 655 HIKKLTSLERLSFSHNKIEVLPSHLFLCNKIRYLDLSYNDIRFIPPEIGVLQSLQYFSIT 714
Query: 386 HNKITEIPYGMSELYVIE----LNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKP 219
NK+ +P ELY + L + +N +S++ + L L + N EI P
Sbjct: 715 CNKVESLP---DELYFCKKLKTLKIGKNSLSVLSPKIGNLLFLSYLDVKGNHF---EILP 768
Query: 218 SLLRDSK 198
L D +
Sbjct: 769 PELGDCR 775
Score = 41.9 bits (94), Expect = 0.002
Identities = 26/86 (30%), Positives = 43/86 (50%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKK 546
++ IP ++ + L+ ++ NK+ LPD+L K LK L + N L L + NL
Sbjct: 695 IRFIPPEI-GVLQSLQYFSITCNKVESLPDELYFCKKLKTLKIGKNSLSVLSPKIGNLLF 753
Query: 545 LEVLNISNNFVQTLPVCLKNLNNLKQ 468
L L++ N + LP L + LK+
Sbjct: 754 LSYLDVKGNHFEILPPELGDCRALKR 779
>BC030608-1|AAH30608.1| 661|Homo sapiens podocan protein.
Length = 661
Score = 70.1 bits (164), Expect = 8e-12
Identities = 56/187 (29%), Positives = 97/187 (51%), Gaps = 9/187 (4%)
Frame = -2
Query: 701 FSLCDVLRNLDLSKNKLS---VLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLN 531
F+ L L+LS N+++ V D KL+ L+ L+L N+L LP L + + VL
Sbjct: 448 FATTYFLEELNLSYNRITSPQVHRDAFRKLRLLRSLDLSGNRLHTLPPGLP--RNVHVLK 505
Query: 530 ISNNFVQTLPV-CLKNLNNLKQVYASNNKLQAF---PKQILGLQSLDVLDLSHNKITEIP 363
+ N + L L + L+++Y ++N+L++ P+ + L L +LD++ N++TEIP
Sbjct: 506 VKRNELAALARGALAGMAQLRELYLTSNRLRSRALGPRAWVDLAHLQLLDIAGNQLTEIP 565
Query: 362 YGMSELYVIELNLSQNEISLI-GEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSK-IHT 189
G+ E + L L N+IS + P LK + L N L++ + S R K +
Sbjct: 566 EGLPE-SLEYLYLQNNKISAVPANAFDSTPNLKGIFLRFNKLAVGSVVDSAFRRLKHLQV 624
Query: 188 VSVDGNL 168
+ ++GNL
Sbjct: 625 LDIEGNL 631
Score = 45.2 bits (102), Expect = 2e-04
Identities = 57/201 (28%), Positives = 90/201 (44%), Gaps = 33/201 (16%)
Frame = -2
Query: 740 IADC---KLKEIPIDVFSLCDVLRNLDLSKNKLS-VLPDDLSKLKHLKQLNLDSNKL--Q 579
+ DC L+E P D L + +L L N+L + P++LS+L L+ LNL +N+L +
Sbjct: 127 VVDCGGIDLREFPGD---LPEHTNHLSLQNNQLEKIYPEELSRLHRLETLNLQNNRLTSR 183
Query: 578 ALPESLI-NLKKLEVLNISNNFVQTLPVCLKNL----------------------NNLKQ 468
LPE +L L L ++NN + P L N NL+
Sbjct: 184 GLPEKAFEHLTNLNYLYLANNKLTLAPRFLPNALISVDFAANYLTKIYGLTFGQKPNLRS 243
Query: 467 VYASNNKL--QAFPKQIL-GLQSLDVLDLSHNKITEIPYGMSELYVIELNLSQNEISLIG 297
VY NNKL P + G +++VL LS N + +P + + +L+L N++ I
Sbjct: 244 VYLHNNKLADAGLPDNMFNGSSNVEVLILSSNFLRHVPKHLPPA-LYKLHLKNNKLEKIP 302
Query: 296 ED-LHQAPRLKILRLDENCLS 237
+ L+ L L N L+
Sbjct: 303 PGAFSELSSLRELYLQNNYLT 323
>BC028292-1|AAH28292.1| 402|Homo sapiens PODN protein protein.
Length = 402
Score = 70.1 bits (164), Expect = 8e-12
Identities = 56/187 (29%), Positives = 97/187 (51%), Gaps = 9/187 (4%)
Frame = -2
Query: 701 FSLCDVLRNLDLSKNKLS---VLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLN 531
F+ L L+LS N+++ V D KL+ L+ L+L N+L LP L + + VL
Sbjct: 189 FATTYFLEELNLSYNRITSPQVHRDAFRKLRLLRSLDLSGNRLHTLPPGLP--RNVHVLK 246
Query: 530 ISNNFVQTLPV-CLKNLNNLKQVYASNNKLQAF---PKQILGLQSLDVLDLSHNKITEIP 363
+ N + L L + L+++Y ++N+L++ P+ + L L +LD++ N++TEIP
Sbjct: 247 VKRNELAALARGALAGMAQLRELYLTSNRLRSRALGPRAWVDLAHLQLLDIAGNQLTEIP 306
Query: 362 YGMSELYVIELNLSQNEISLI-GEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSK-IHT 189
G+ E + L L N+IS + P LK + L N L++ + S R K +
Sbjct: 307 EGLPE-SLEYLYLQNNKISAVPANAFDSTPNLKGIFLRFNKLAVGSVVDSAFRRLKHLQV 365
Query: 188 VSVDGNL 168
+ ++GNL
Sbjct: 366 LDIEGNL 372
>AY358294-1|AAQ88661.1| 642|Homo sapiens EGEE293 protein.
Length = 642
Score = 70.1 bits (164), Expect = 8e-12
Identities = 56/187 (29%), Positives = 97/187 (51%), Gaps = 9/187 (4%)
Frame = -2
Query: 701 FSLCDVLRNLDLSKNKLS---VLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLN 531
F+ L L+LS N+++ V D KL+ L+ L+L N+L LP L + + VL
Sbjct: 429 FATTYFLEELNLSYNRITSPQVHRDAFRKLRLLRSLDLSGNRLHTLPPGLP--RNVHVLK 486
Query: 530 ISNNFVQTLPV-CLKNLNNLKQVYASNNKLQAF---PKQILGLQSLDVLDLSHNKITEIP 363
+ N + L L + L+++Y ++N+L++ P+ + L L +LD++ N++TEIP
Sbjct: 487 VKRNELAALARGALAGMAQLRELYLTSNRLRSRALGPRAWVDLAHLQLLDIAGNQLTEIP 546
Query: 362 YGMSELYVIELNLSQNEISLI-GEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSK-IHT 189
G+ E + L L N+IS + P LK + L N L++ + S R K +
Sbjct: 547 EGLPE-SLEYLYLQNNKISAVPANAFDSTPNLKGIFLRFNKLAVGSVVDSAFRRLKHLQV 605
Query: 188 VSVDGNL 168
+ ++GNL
Sbjct: 606 LDIEGNL 612
Score = 45.2 bits (102), Expect = 2e-04
Identities = 57/201 (28%), Positives = 90/201 (44%), Gaps = 33/201 (16%)
Frame = -2
Query: 740 IADC---KLKEIPIDVFSLCDVLRNLDLSKNKLS-VLPDDLSKLKHLKQLNLDSNKL--Q 579
+ DC L+E P D L + +L L N+L + P++LS+L L+ LNL +N+L +
Sbjct: 108 VVDCGGIDLREFPGD---LPEHTNHLSLQNNQLEKIYPEELSRLHRLETLNLQNNRLTSR 164
Query: 578 ALPESLI-NLKKLEVLNISNNFVQTLPVCLKNL----------------------NNLKQ 468
LPE +L L L ++NN + P L N NL+
Sbjct: 165 GLPEKAFEHLTNLNYLYLANNKLTLAPRFLPNALISVDFAANYLTKIYGLTFGQKPNLRS 224
Query: 467 VYASNNKL--QAFPKQIL-GLQSLDVLDLSHNKITEIPYGMSELYVIELNLSQNEISLIG 297
VY NNKL P + G +++VL LS N + +P + + +L+L N++ I
Sbjct: 225 VYLHNNKLADAGLPDNMFNGSSNVEVLILSSNFLRHVPKHLPPA-LYKLHLKNNKLEKIP 283
Query: 296 ED-LHQAPRLKILRLDENCLS 237
+ L+ L L N L+
Sbjct: 284 PGAFSELSSLRELYLQNNYLT 304
>AB081509-1|BAB86303.1| 803|Homo sapiens AD158 protein.
Length = 803
Score = 70.1 bits (164), Expect = 8e-12
Identities = 57/187 (30%), Positives = 91/187 (48%), Gaps = 6/187 (3%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLS--KLKHLKQLNLDSNKLQALPE 567
+ C L+ IP VFSL L+ LDL +N L + + +S L+ L L L N + +PE
Sbjct: 596 LVHCDLERIPHAVFSLLS-LQELDLKENNLKSIEEIVSFQHLRKLTVLKLWHNSITYIPE 654
Query: 566 SLINLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLS 387
+ L LE L+ S+N ++ LP L N ++ + S N ++ P +I LQSL ++
Sbjct: 655 HIKKLTSLERLSFSHNKIEVLPSHLFLCNKIRYLDLSYNDIRFIPPEIGVLQSLQYFSIT 714
Query: 386 HNKITEIPYGMSELYVIE----LNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKP 219
NK+ +P ELY + L + +N +S++ + L L + N EI P
Sbjct: 715 CNKVESLP---DELYFCKKLKTLKIGKNSLSVLSPKIGNLLFLSYLDVKGNHF---EILP 768
Query: 218 SLLRDSK 198
L D +
Sbjct: 769 PELGDCR 775
Score = 41.9 bits (94), Expect = 0.002
Identities = 26/86 (30%), Positives = 43/86 (50%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKK 546
++ IP ++ + L+ ++ NK+ LPD+L K LK L + N L L + NL
Sbjct: 695 IRFIPPEI-GVLQSLQYFSITCNKVESLPDELYFCKKLKTLKIGKNSLSVLSPKIGNLLF 753
Query: 545 LEVLNISNNFVQTLPVCLKNLNNLKQ 468
L L++ N + LP L + LK+
Sbjct: 754 LSYLDVKGNHFEILPPELGDCRALKR 779
>AY313607-1|AAP79898.1| 613|Homo sapiens podocan protein protein.
Length = 613
Score = 69.7 bits (163), Expect = 1e-11
Identities = 56/187 (29%), Positives = 97/187 (51%), Gaps = 9/187 (4%)
Frame = -2
Query: 701 FSLCDVLRNLDLSKNKLS---VLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLN 531
F+ L L+LS N+++ V D KL+ L+ L+L N+L LP L + + VL
Sbjct: 400 FATTYFLEELNLSYNRITSPQVHRDAFRKLRLLRSLDLSGNRLHMLPPGLP--RNVHVLK 457
Query: 530 ISNNFVQTLPV-CLKNLNNLKQVYASNNKLQAF---PKQILGLQSLDVLDLSHNKITEIP 363
+ N + L L + L+++Y ++N+L++ P+ + L L +LD++ N++TEIP
Sbjct: 458 VKRNELAALARGALAGMAQLRELYLTSNRLRSRALGPRAWVDLAHLQLLDIAGNQLTEIP 517
Query: 362 YGMSELYVIELNLSQNEISLI-GEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSK-IHT 189
G+ E + L L N+IS + P LK + L N L++ + S R K +
Sbjct: 518 EGLPE-SLEYLYLQNNKISAVPANAFDSTPNLKGIFLRFNKLAVGSVVDSAFRRLKHLQV 576
Query: 188 VSVDGNL 168
+ ++GNL
Sbjct: 577 LDIEGNL 583
Score = 45.2 bits (102), Expect = 2e-04
Identities = 57/201 (28%), Positives = 90/201 (44%), Gaps = 33/201 (16%)
Frame = -2
Query: 740 IADC---KLKEIPIDVFSLCDVLRNLDLSKNKLS-VLPDDLSKLKHLKQLNLDSNKL--Q 579
+ DC L+E P D L + +L L N+L + P++LS+L L+ LNL +N+L +
Sbjct: 79 VVDCGGIDLREFPGD---LPEHTNHLSLQNNQLEKIYPEELSRLHRLETLNLQNNRLTSR 135
Query: 578 ALPESLI-NLKKLEVLNISNNFVQTLPVCLKNL----------------------NNLKQ 468
LPE +L L L ++NN + P L N NL+
Sbjct: 136 GLPEKAFEHLTNLNYLYLANNKLTLAPRFLPNALISVDFAANYLTKIYGLTFGQKPNLRS 195
Query: 467 VYASNNKL--QAFPKQIL-GLQSLDVLDLSHNKITEIPYGMSELYVIELNLSQNEISLIG 297
VY NNKL P + G +++VL LS N + +P + + +L+L N++ I
Sbjct: 196 VYLHNNKLADAGLPDNMFNGSSNVEVLILSSNFLRHVPKHLPPA-LYKLHLKNNKLEKIP 254
Query: 296 ED-LHQAPRLKILRLDENCLS 237
+ L+ L L N L+
Sbjct: 255 PGAFSELSSLRELYLQNNYLT 275
>AL445183-5|CAH72592.1| 642|Homo sapiens podocan protein.
Length = 642
Score = 69.7 bits (163), Expect = 1e-11
Identities = 56/187 (29%), Positives = 97/187 (51%), Gaps = 9/187 (4%)
Frame = -2
Query: 701 FSLCDVLRNLDLSKNKLS---VLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLN 531
F+ L L+LS N+++ V D KL+ L+ L+L N+L LP L + + VL
Sbjct: 429 FATTYFLEELNLSYNRITSPQVHRDAFRKLRLLRSLDLSGNRLHTLPPGLP--RNVHVLK 486
Query: 530 ISNNFVQTLPV-CLKNLNNLKQVYASNNKLQAF---PKQILGLQSLDVLDLSHNKITEIP 363
+ N + L L + L+++Y ++N+L++ P+ + L L +LD++ N++TEIP
Sbjct: 487 VKRNELAALARGALVGMAQLRELYLTSNRLRSRALGPRAWVDLAHLQLLDIAGNQLTEIP 546
Query: 362 YGMSELYVIELNLSQNEISLI-GEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSK-IHT 189
G+ E + L L N+IS + P LK + L N L++ + S R K +
Sbjct: 547 EGLPE-SLEYLYLQNNKISAVPANAFDSTPNLKGIFLRFNKLAVGSVVDSAFRRLKHLQV 605
Query: 188 VSVDGNL 168
+ ++GNL
Sbjct: 606 LDIEGNL 612
Score = 45.2 bits (102), Expect = 2e-04
Identities = 57/201 (28%), Positives = 90/201 (44%), Gaps = 33/201 (16%)
Frame = -2
Query: 740 IADC---KLKEIPIDVFSLCDVLRNLDLSKNKLS-VLPDDLSKLKHLKQLNLDSNKL--Q 579
+ DC L+E P D L + +L L N+L + P++LS+L L+ LNL +N+L +
Sbjct: 108 VVDCGGIDLREFPGD---LPEHTNHLSLQNNQLEKIYPEELSRLHRLETLNLQNNRLTSR 164
Query: 578 ALPESLI-NLKKLEVLNISNNFVQTLPVCLKNL----------------------NNLKQ 468
LPE +L L L ++NN + P L N NL+
Sbjct: 165 GLPEKAFEHLTNLNYLYLANNKLTLAPRFLPNALISVDFAANYLTKIYGLTFGQKPNLRS 224
Query: 467 VYASNNKL--QAFPKQIL-GLQSLDVLDLSHNKITEIPYGMSELYVIELNLSQNEISLIG 297
VY NNKL P + G +++VL LS N + +P + + +L+L N++ I
Sbjct: 225 VYLHNNKLADAGLPDNMFNGSSNVEVLILSSNFLRHVPKHLPPA-LYKLHLKNNKLEKIP 283
Query: 296 ED-LHQAPRLKILRLDENCLS 237
+ L+ L L N L+
Sbjct: 284 PGAFSELSSLRELYLQNNYLT 304
>AL445183-4|CAH72591.1| 661|Homo sapiens podocan protein.
Length = 661
Score = 69.7 bits (163), Expect = 1e-11
Identities = 56/187 (29%), Positives = 97/187 (51%), Gaps = 9/187 (4%)
Frame = -2
Query: 701 FSLCDVLRNLDLSKNKLS---VLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLN 531
F+ L L+LS N+++ V D KL+ L+ L+L N+L LP L + + VL
Sbjct: 448 FATTYFLEELNLSYNRITSPQVHRDAFRKLRLLRSLDLSGNRLHTLPPGLP--RNVHVLK 505
Query: 530 ISNNFVQTLPV-CLKNLNNLKQVYASNNKLQAF---PKQILGLQSLDVLDLSHNKITEIP 363
+ N + L L + L+++Y ++N+L++ P+ + L L +LD++ N++TEIP
Sbjct: 506 VKRNELAALARGALVGMAQLRELYLTSNRLRSRALGPRAWVDLAHLQLLDIAGNQLTEIP 565
Query: 362 YGMSELYVIELNLSQNEISLI-GEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSK-IHT 189
G+ E + L L N+IS + P LK + L N L++ + S R K +
Sbjct: 566 EGLPE-SLEYLYLQNNKISAVPANAFDSTPNLKGIFLRFNKLAVGSVVDSAFRRLKHLQV 624
Query: 188 VSVDGNL 168
+ ++GNL
Sbjct: 625 LDIEGNL 631
Score = 45.2 bits (102), Expect = 2e-04
Identities = 57/201 (28%), Positives = 90/201 (44%), Gaps = 33/201 (16%)
Frame = -2
Query: 740 IADC---KLKEIPIDVFSLCDVLRNLDLSKNKLS-VLPDDLSKLKHLKQLNLDSNKL--Q 579
+ DC L+E P D L + +L L N+L + P++LS+L L+ LNL +N+L +
Sbjct: 127 VVDCGGIDLREFPGD---LPEHTNHLSLQNNQLEKIYPEELSRLHRLETLNLQNNRLTSR 183
Query: 578 ALPESLI-NLKKLEVLNISNNFVQTLPVCLKNL----------------------NNLKQ 468
LPE +L L L ++NN + P L N NL+
Sbjct: 184 GLPEKAFEHLTNLNYLYLANNKLTLAPRFLPNALISVDFAANYLTKIYGLTFGQKPNLRS 243
Query: 467 VYASNNKL--QAFPKQIL-GLQSLDVLDLSHNKITEIPYGMSELYVIELNLSQNEISLIG 297
VY NNKL P + G +++VL LS N + +P + + +L+L N++ I
Sbjct: 244 VYLHNNKLADAGLPDNMFNGSSNVEVLILSSNFLRHVPKHLPPA-LYKLHLKNNKLEKIP 302
Query: 296 ED-LHQAPRLKILRLDENCLS 237
+ L+ L L N L+
Sbjct: 303 PGAFSELSSLRELYLQNNYLT 323
>Z23091-1|CAA80637.1| 560|Homo sapiens platelet glycoprotein V
precursor protein.
Length = 560
Score = 68.9 bits (161), Expect = 2e-11
Identities = 58/175 (33%), Positives = 89/175 (50%), Gaps = 7/175 (4%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDL-SKLKHLKQLNLDSNKLQALPES 564
I+D + + FS L+ L LS+NK++ LP L K+ L+QL LD N L+ + ++
Sbjct: 81 ISDSHISAVAPGTFSDLIKLKTLRLSRNKITHLPGALLDKMVLLEQLFLDHNALRGIDQN 140
Query: 563 LIN-LKKLEVLNISNNFVQTLPVCL-KNLNNLKQVYASNNKLQAFPKQILGLQS-LDVLD 393
+ L L+ L ++ N + LP L NL NLK + S N L PK +LG Q+ L+ L
Sbjct: 141 MFQKLVNLQELALNQNQLDFLPASLFTNLENLKLLDLSGNNLTHLPKGLLGAQAKLERLL 200
Query: 392 LSHNKITEIPYGM--SELYVIELNLSQNEI-SLIGEDLHQAPRLKILRLDENCLS 237
L N++ + G+ S + EL +N I S+ + P L L L N L+
Sbjct: 201 LHSNRLVSLDSGLLNSLGALTELQFHRNHIRSIAPGAFDRLPNLSSLTLSRNHLA 255
Score = 49.6 bits (113), Expect = 1e-05
Identities = 30/78 (38%), Positives = 46/78 (58%), Gaps = 2/78 (2%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSK-LKHLKQLNLDSNKLQALPESLI-N 555
+L +P F L+ L L N L+ LPD L + L L+Q++L N+L+ALP +L N
Sbjct: 326 RLSALPQGAFQGLGELQVLALHSNGLTALPDGLLRGLGKLRQVSLRRNRLRALPRALFRN 385
Query: 554 LKKLEVLNISNNFVQTLP 501
L LE + + +N ++TLP
Sbjct: 386 LSSLESVQLDHNQLETLP 403
>L11238-1|AAA03069.1| 560|Homo sapiens platelet membrane
glycoprotein V protein.
Length = 560
Score = 68.9 bits (161), Expect = 2e-11
Identities = 58/175 (33%), Positives = 89/175 (50%), Gaps = 7/175 (4%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDL-SKLKHLKQLNLDSNKLQALPES 564
I+D + + FS L+ L LS+NK++ LP L K+ L+QL LD N L+ + ++
Sbjct: 81 ISDSHISAVAPGTFSDLIKLKTLRLSRNKITHLPGALLDKMVLLEQLFLDHNALRGIDQN 140
Query: 563 LIN-LKKLEVLNISNNFVQTLPVCL-KNLNNLKQVYASNNKLQAFPKQILGLQS-LDVLD 393
+ L L+ L ++ N + LP L NL NLK + S N L PK +LG Q+ L+ L
Sbjct: 141 MFQKLVNLQELALNQNQLDFLPASLFTNLENLKLLDLSGNNLTHLPKGLLGAQAKLERLL 200
Query: 392 LSHNKITEIPYGM--SELYVIELNLSQNEI-SLIGEDLHQAPRLKILRLDENCLS 237
L N++ + G+ S + EL +N I S+ + P L L L N L+
Sbjct: 201 LHSNRLVSLDSGLLNSLGALTELQFHRNHIRSIAPGAFDRLPNLSSLTLSRNHLA 255
Score = 49.6 bits (113), Expect = 1e-05
Identities = 30/78 (38%), Positives = 46/78 (58%), Gaps = 2/78 (2%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSK-LKHLKQLNLDSNKLQALPESLI-N 555
+L +P F L+ L L N L+ LPD L + L L+Q++L N+L+ALP +L N
Sbjct: 326 RLSALPQGAFQGLGELQVLALHSNGLTALPDGLLRGLGKLRQVSLRRNRLRALPRALFRN 385
Query: 554 LKKLEVLNISNNFVQTLP 501
L LE + + +N ++TLP
Sbjct: 386 LSSLESVQLDHNQLETLP 403
>U41344-1|AAC18782.1| 382|Homo sapiens prolargin protein.
Length = 382
Score = 67.3 bits (157), Expect = 5e-11
Identities = 59/182 (32%), Positives = 87/182 (47%), Gaps = 20/182 (10%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLS---VLPDDLSKLKHLKQLNLDSNKLQALPESLIN 555
+ IP VFS + L LDL N+LS PD LK+L QLNL N L+ +P +
Sbjct: 183 ISRIPPGVFSKLENLLLLDLQHNRLSDGVFKPDTFHGLKNLMQLNLAHNILRKMPPRVPT 242
Query: 554 LKKLEVLNISNNFVQTLPV-CLKNLNNLKQVYASNNKL--QAFPKQILGLQSLDVLDLSH 384
+ L + +N ++T+P K+ NL + + NKL + PK + +L VL LSH
Sbjct: 243 A--IHQLYLDSNKIETIPNGYFKSFPNLAFIRLNYNKLTDRGLPKNSFNISNLLVLHLSH 300
Query: 383 NKITEIPYGMSELYVIELN-----------LSQNEISL---IGEDLHQAPRLKILRLDEN 246
N+I+ +P + L + LN + N++ DL P L+ LRLD N
Sbjct: 301 NRISSVPAINNRLEHLYLNNNSIEKINGTQICPNDLVAFHDFSSDLENVPHLRYLRLDGN 360
Query: 245 CL 240
L
Sbjct: 361 YL 362
Score = 49.2 bits (112), Expect = 2e-05
Identities = 40/139 (28%), Positives = 66/139 (47%), Gaps = 3/139 (2%)
Frame = -2
Query: 605 LNLDSNKLQALPESLINLKKLEVLNISNNFVQTLPV-CLKNLNNLKQVYASNNKLQAFPK 429
L DS L+ +P + ++ L + NNF+ LPV +N L+ + NN+++ +
Sbjct: 87 LYCDSRNLRKVP---VIPPRIHYLYLQNNFITELPVESFQNATGLRWINLDNNRIRKIDQ 143
Query: 428 QIL-GLQSLDVLDLSHNKITEIPYGMSELYVIELNLSQNEISLIGEDL-HQAPRLKILRL 255
++L L L L + N++ E+P + + +L LSQN IS I + + L +L L
Sbjct: 144 RVLEKLPGLVFLYMEKNQLEEVPSALPR-NLEQLRLSQNHISRIPPGVFSKLENLLLLDL 202
Query: 254 DENCLSLDEIKPSLLRDSK 198
N LS KP K
Sbjct: 203 QHNRLSDGVFKPDTFHGLK 221
>U29089-1|AAC50230.1| 382|Homo sapiens proline- arginine-rich end
leucine-rich repeat protein protein.
Length = 382
Score = 67.3 bits (157), Expect = 5e-11
Identities = 59/182 (32%), Positives = 87/182 (47%), Gaps = 20/182 (10%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLS---VLPDDLSKLKHLKQLNLDSNKLQALPESLIN 555
+ IP VFS + L LDL N+LS PD LK+L QLNL N L+ +P +
Sbjct: 183 ISRIPPGVFSKLENLLLLDLQHNRLSDGVFKPDTFHGLKNLMQLNLAHNILRKMPPRVPT 242
Query: 554 LKKLEVLNISNNFVQTLPV-CLKNLNNLKQVYASNNKL--QAFPKQILGLQSLDVLDLSH 384
+ L + +N ++T+P K+ NL + + NKL + PK + +L VL LSH
Sbjct: 243 A--IHQLYLDSNKIETIPNGYFKSFPNLAFIRLNYNKLTDRGLPKNSFNISNLLVLHLSH 300
Query: 383 NKITEIPYGMSELYVIELN-----------LSQNEISL---IGEDLHQAPRLKILRLDEN 246
N+I+ +P + L + LN + N++ DL P L+ LRLD N
Sbjct: 301 NRISSVPAINNRLEHLYLNNNSIEKINGTQICPNDLVAFHDFSSDLENVPHLRYLRLDGN 360
Query: 245 CL 240
L
Sbjct: 361 YL 362
Score = 49.2 bits (112), Expect = 2e-05
Identities = 40/139 (28%), Positives = 66/139 (47%), Gaps = 3/139 (2%)
Frame = -2
Query: 605 LNLDSNKLQALPESLINLKKLEVLNISNNFVQTLPV-CLKNLNNLKQVYASNNKLQAFPK 429
L DS L+ +P + ++ L + NNF+ LPV +N L+ + NN+++ +
Sbjct: 87 LYCDSRNLRKVP---VIPPRIHYLYLQNNFITELPVESFQNATGLRWINLDNNRIRKIDQ 143
Query: 428 QIL-GLQSLDVLDLSHNKITEIPYGMSELYVIELNLSQNEISLIGEDL-HQAPRLKILRL 255
++L L L L + N++ E+P + + +L LSQN IS I + + L +L L
Sbjct: 144 RVLEKLPGLVFLYMEKNQLEEVPSALPR-NLEQLRLSQNHISRIPPGVFSKLENLLLLDL 202
Query: 254 DENCLSLDEIKPSLLRDSK 198
N LS KP K
Sbjct: 203 QHNRLSDGVFKPDTFHGLK 221
>CR542270-1|CAG47066.1| 382|Homo sapiens PRELP protein.
Length = 382
Score = 67.3 bits (157), Expect = 5e-11
Identities = 59/182 (32%), Positives = 87/182 (47%), Gaps = 20/182 (10%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLS---VLPDDLSKLKHLKQLNLDSNKLQALPESLIN 555
+ IP VFS + L LDL N+LS PD LK+L QLNL N L+ +P +
Sbjct: 183 ISRIPPGVFSKLENLLLLDLQHNRLSDGVFKPDTFHGLKNLMQLNLAHNILRKMPPRVPT 242
Query: 554 LKKLEVLNISNNFVQTLPV-CLKNLNNLKQVYASNNKL--QAFPKQILGLQSLDVLDLSH 384
+ L + +N ++T+P K+ NL + + NKL + PK + +L VL LSH
Sbjct: 243 A--IHQLYLDSNKIETIPNGYFKSFPNLAFIRLNYNKLTDRGLPKNSFNISNLLVLHLSH 300
Query: 383 NKITEIPYGMSELYVIELN-----------LSQNEISL---IGEDLHQAPRLKILRLDEN 246
N+I+ +P + L + LN + N++ DL P L+ LRLD N
Sbjct: 301 NRISSVPAINNRLEHLYLNNNSIEKINGTQICPNDLVAFHDFSSDLENVPHLRYLRLDGN 360
Query: 245 CL 240
L
Sbjct: 361 YL 362
Score = 49.2 bits (112), Expect = 2e-05
Identities = 40/139 (28%), Positives = 66/139 (47%), Gaps = 3/139 (2%)
Frame = -2
Query: 605 LNLDSNKLQALPESLINLKKLEVLNISNNFVQTLPV-CLKNLNNLKQVYASNNKLQAFPK 429
L DS L+ +P + ++ L + NNF+ LPV +N L+ + NN+++ +
Sbjct: 87 LYCDSRNLRKVP---VIPPRIHYLYLQNNFITELPVESFQNATGLRWINLDNNRIRKIDQ 143
Query: 428 QIL-GLQSLDVLDLSHNKITEIPYGMSELYVIELNLSQNEISLIGEDL-HQAPRLKILRL 255
++L L L L + N++ E+P + + +L LSQN IS I + + L +L L
Sbjct: 144 RVLEKLPGLVFLYMEKNQLEEVPSALPR-NLEQLRLSQNHISRIPPGVFSKLENLLLLDL 202
Query: 254 DENCLSLDEIKPSLLRDSK 198
N LS KP K
Sbjct: 203 QHNRLSDGVFKPDTFHGLK 221
>CR541787-1|CAG46586.1| 382|Homo sapiens PRELP protein.
Length = 382
Score = 67.3 bits (157), Expect = 5e-11
Identities = 59/182 (32%), Positives = 87/182 (47%), Gaps = 20/182 (10%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLS---VLPDDLSKLKHLKQLNLDSNKLQALPESLIN 555
+ IP VFS + L LDL N+LS PD LK+L QLNL N L+ +P +
Sbjct: 183 ISRIPPGVFSKLENLLLLDLQHNRLSDGVFKPDTFHGLKNLMQLNLAHNILRKMPPRVPT 242
Query: 554 LKKLEVLNISNNFVQTLPV-CLKNLNNLKQVYASNNKL--QAFPKQILGLQSLDVLDLSH 384
+ L + +N ++T+P K+ NL + + NKL + PK + +L VL LSH
Sbjct: 243 A--IHQLYLDSNKIETIPNGYFKSFPNLAFIRLNYNKLTDRGLPKNSFNISNLLVLHLSH 300
Query: 383 NKITEIPYGMSELYVIELN-----------LSQNEISL---IGEDLHQAPRLKILRLDEN 246
N+I+ +P + L + LN + N++ DL P L+ LRLD N
Sbjct: 301 NRISSVPAINNRLEHLYLNNNSIEKINGTQICPNDLVAFHDFSSDLENVPHLRYLRLDGN 360
Query: 245 CL 240
L
Sbjct: 361 YL 362
>BC042334-1|AAH42334.2| 545|Homo sapiens carboxypeptidase N,
polypeptide 2 protein.
Length = 545
Score = 67.3 bits (157), Expect = 5e-11
Identities = 45/125 (36%), Positives = 65/125 (52%), Gaps = 4/125 (3%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSK-LKHLKQLNLDSNKLQALPESLIN-L 552
L+ +P +F L +L L N+L LP L + L HLK LNL N L LPE L + L
Sbjct: 133 LEALPEGLFQHLAALESLHLQGNRLQALPRRLFQPLTHLKTLNLAQNLLAQLPEELFHPL 192
Query: 551 KKLEVLNISNNFVQTLPV-CLKNLNNLKQVYASNNKLQAFPKQILG-LQSLDVLDLSHNK 378
L+ L +SNN + LP L +L++++ +N + P Q+ L L+ L L N
Sbjct: 193 TSLQTLKLSNNALSGLPQGVFGKLGSLQELFLDSNNISELPPQVFSQLFCLERLWLQRNA 252
Query: 377 ITEIP 363
IT +P
Sbjct: 253 ITHLP 257
Score = 46.4 bits (105), Expect = 1e-04
Identities = 36/99 (36%), Positives = 55/99 (55%), Gaps = 3/99 (3%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSK-LKHLKQLNLDSNKLQALPESLI-N 555
+L+ + F+ LR+L LS N ++ LP + + L+ L +L L SN L AL +L N
Sbjct: 300 QLETVAEGTFAHLSNLRSLMLSYNAITHLPAGIFRDLEELVKLYLGSNNLTALHPALFQN 359
Query: 554 LKKLEVLNISNNFVQTLPVCLKNLN-NLKQVYASNNKLQ 441
L KLE+L++S N + TLP + + N NL + N Q
Sbjct: 360 LSKLELLSLSKNQLTTLPEGIFDTNYNLFNLALHGNPWQ 398
>BC032498-1|AAH32498.1| 382|Homo sapiens proline/arginine-rich end
leucine-rich repeat protein protein.
Length = 382
Score = 67.3 bits (157), Expect = 5e-11
Identities = 59/182 (32%), Positives = 87/182 (47%), Gaps = 20/182 (10%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLS---VLPDDLSKLKHLKQLNLDSNKLQALPESLIN 555
+ IP VFS + L LDL N+LS PD LK+L QLNL N L+ +P +
Sbjct: 183 ISRIPPGVFSKLENLLLLDLQHNRLSDGVFKPDTFHGLKNLMQLNLAHNILRKMPPRVPT 242
Query: 554 LKKLEVLNISNNFVQTLPV-CLKNLNNLKQVYASNNKL--QAFPKQILGLQSLDVLDLSH 384
+ L + +N ++T+P K+ NL + + NKL + PK + +L VL LSH
Sbjct: 243 A--IHQLYLDSNKIETIPNGYFKSFPNLAFIRLNYNKLTDRGLPKNSFNISNLLVLHLSH 300
Query: 383 NKITEIPYGMSELYVIELN-----------LSQNEISL---IGEDLHQAPRLKILRLDEN 246
N+I+ +P + L + LN + N++ DL P L+ LRLD N
Sbjct: 301 NRISSVPAINNRLEHLYLNNNSIEKINGTQICPNDLVAFHDFSSDLENVPHLRYLRLDGN 360
Query: 245 CL 240
L
Sbjct: 361 YL 362
Score = 49.2 bits (112), Expect = 2e-05
Identities = 40/139 (28%), Positives = 66/139 (47%), Gaps = 3/139 (2%)
Frame = -2
Query: 605 LNLDSNKLQALPESLINLKKLEVLNISNNFVQTLPV-CLKNLNNLKQVYASNNKLQAFPK 429
L DS L+ +P + ++ L + NNF+ LPV +N L+ + NN+++ +
Sbjct: 87 LYCDSRNLRKVP---VIPPRIHYLYLQNNFITELPVESFQNATGLRWINLDNNRIRKIDQ 143
Query: 428 QIL-GLQSLDVLDLSHNKITEIPYGMSELYVIELNLSQNEISLIGEDL-HQAPRLKILRL 255
++L L L L + N++ E+P + + +L LSQN IS I + + L +L L
Sbjct: 144 RVLEKLPGLVFLYMEKNQLEEVPSALPR-NLEQLRLSQNHISRIPPGVFSKLENLLLLDL 202
Query: 254 DENCLSLDEIKPSLLRDSK 198
N LS KP K
Sbjct: 203 QHNRLSDGVFKPDTFHGLK 221
>AL391817-1|CAI17033.1| 382|Homo sapiens proline/arginine-rich end
leucine-rich repeat protein protein.
Length = 382
Score = 67.3 bits (157), Expect = 5e-11
Identities = 59/182 (32%), Positives = 87/182 (47%), Gaps = 20/182 (10%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLS---VLPDDLSKLKHLKQLNLDSNKLQALPESLIN 555
+ IP VFS + L LDL N+LS PD LK+L QLNL N L+ +P +
Sbjct: 183 ISRIPPGVFSKLENLLLLDLQHNRLSDGVFKPDTFHGLKNLMQLNLAHNILRKMPPRVPT 242
Query: 554 LKKLEVLNISNNFVQTLPV-CLKNLNNLKQVYASNNKL--QAFPKQILGLQSLDVLDLSH 384
+ L + +N ++T+P K+ NL + + NKL + PK + +L VL LSH
Sbjct: 243 A--IHQLYLDSNKIETIPNGYFKSFPNLAFIRLNYNKLTDRGLPKNSFNISNLLVLHLSH 300
Query: 383 NKITEIPYGMSELYVIELN-----------LSQNEISL---IGEDLHQAPRLKILRLDEN 246
N+I+ +P + L + LN + N++ DL P L+ LRLD N
Sbjct: 301 NRISSVPAINNRLEHLYLNNNSIEKINGTQICPNDLVAFHDFSSDLENVPHLRYLRLDGN 360
Query: 245 CL 240
L
Sbjct: 361 YL 362
Score = 49.2 bits (112), Expect = 2e-05
Identities = 40/139 (28%), Positives = 66/139 (47%), Gaps = 3/139 (2%)
Frame = -2
Query: 605 LNLDSNKLQALPESLINLKKLEVLNISNNFVQTLPV-CLKNLNNLKQVYASNNKLQAFPK 429
L DS L+ +P + ++ L + NNF+ LPV +N L+ + NN+++ +
Sbjct: 87 LYCDSRNLRKVP---VIPPRIHYLYLQNNFITELPVESFQNATGLRWINLDNNRIRKIDQ 143
Query: 428 QIL-GLQSLDVLDLSHNKITEIPYGMSELYVIELNLSQNEISLIGEDL-HQAPRLKILRL 255
++L L L L + N++ E+P + + +L LSQN IS I + + L +L L
Sbjct: 144 RVLEKLPGLVFLYMEKNQLEEVPSALPR-NLEQLRLSQNHISRIPPGVFSKLENLLLLDL 202
Query: 254 DENCLSLDEIKPSLLRDSK 198
N LS KP K
Sbjct: 203 QHNRLSDGVFKPDTFHGLK 221
>J05158-1|AAA51921.2| 545|Homo sapiens carboxypeptidase N precursor
protein.
Length = 545
Score = 66.9 bits (156), Expect = 7e-11
Identities = 45/125 (36%), Positives = 65/125 (52%), Gaps = 4/125 (3%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSK-LKHLKQLNLDSNKLQALPESLIN-L 552
L+ +P +F L +L L N+L LP L + L HLK LNL N L LPE L + L
Sbjct: 133 LEALPEGLFQHLAALESLHLQGNQLQALPRRLFQPLTHLKTLNLAQNLLAQLPEELFHPL 192
Query: 551 KKLEVLNISNNFVQTLPV-CLKNLNNLKQVYASNNKLQAFPKQILG-LQSLDVLDLSHNK 378
L+ L +SNN + LP L +L++++ +N + P Q+ L L+ L L N
Sbjct: 193 TSLQTLKLSNNALSGLPQGVFGKLGSLQELFLDSNNISELPPQVFSQLFCLERLWLQRNA 252
Query: 377 ITEIP 363
IT +P
Sbjct: 253 ITHLP 257
Score = 46.4 bits (105), Expect = 1e-04
Identities = 36/99 (36%), Positives = 55/99 (55%), Gaps = 3/99 (3%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSK-LKHLKQLNLDSNKLQALPESLI-N 555
+L+ + F+ LR+L LS N ++ LP + + L+ L +L L SN L AL +L N
Sbjct: 300 QLETVAEGTFAHLSNLRSLMLSYNAITHLPAGIFRDLEELVKLYLGSNNLTALHPALFQN 359
Query: 554 LKKLEVLNISNNFVQTLPVCLKNLN-NLKQVYASNNKLQ 441
L KLE+L++S N + TLP + + N NL + N Q
Sbjct: 360 LSKLELLSLSKNQLTTLPEGIFDTNYNLFNLALHGNPWQ 398
>BC031569-1|AAH31569.2| 545|Homo sapiens carboxypeptidase N,
polypeptide 2 protein.
Length = 545
Score = 66.9 bits (156), Expect = 7e-11
Identities = 45/125 (36%), Positives = 65/125 (52%), Gaps = 4/125 (3%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSK-LKHLKQLNLDSNKLQALPESLIN-L 552
L+ +P +F L +L L N+L LP L + L HLK LNL N L LPE L + L
Sbjct: 133 LEALPEGLFQHLAALESLHLQGNQLQALPRRLFQPLTHLKTLNLAQNLLAQLPEELFHPL 192
Query: 551 KKLEVLNISNNFVQTLPV-CLKNLNNLKQVYASNNKLQAFPKQILG-LQSLDVLDLSHNK 378
L+ L +SNN + LP L +L++++ +N + P Q+ L L+ L L N
Sbjct: 193 TSLQTLKLSNNALSGLPQGVFGKLGSLQELFLDSNNISELPPQVFSQLFCLERLWLQRNA 252
Query: 377 ITEIP 363
IT +P
Sbjct: 253 ITHLP 257
Score = 46.4 bits (105), Expect = 1e-04
Identities = 36/99 (36%), Positives = 55/99 (55%), Gaps = 3/99 (3%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSK-LKHLKQLNLDSNKLQALPESLI-N 555
+L+ + F+ LR+L LS N ++ LP + + L+ L +L L SN L AL +L N
Sbjct: 300 QLETVAEGTFAHLSNLRSLMLSYNAITHLPAGIFRDLEELVKLYLGSNNLTALHPALFQN 359
Query: 554 LKKLEVLNISNNFVQTLPVCLKNLN-NLKQVYASNNKLQ 441
L KLE+L++S N + TLP + + N NL + N Q
Sbjct: 360 LSKLELLSLSKNQLTTLPEGIFDTNYNLFNLALHGNPWQ 398
>BC007634-1|AAH07634.1| 580|Homo sapiens LRCH4 protein protein.
Length = 580
Score = 66.9 bits (156), Expect = 7e-11
Identities = 50/151 (33%), Positives = 78/151 (51%), Gaps = 2/151 (1%)
Frame = -2
Query: 581 QALPESLINLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLD 402
+ L +L NL L LN+S N + LP + L L+ + SNNKL A P I L SL
Sbjct: 1 RCLNPALGNLTALTYLNLSRNQLSLLPPYICQLP-LRVLIVSNNKLGALPPDIGTLGSLR 59
Query: 401 VLDLSHNKITEIPYGMSELYVI-ELNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEI 225
LD+S N++ +P + L + +LN+ +N++S + E+L P ++RLD +C + I
Sbjct: 60 QLDVSSNELQSLPSELCGLSSLRDLNVRRNQLSTLPEELGDLP---LVRLDFSCNRVSRI 116
Query: 224 KPSLLRDSKIHTVSVDGN-LFEPKQLAXLEG 135
S R + + +D N L P L+G
Sbjct: 117 PVSFCRLRHLQVILLDSNPLQSPPAQVCLKG 147
Score = 66.9 bits (156), Expect = 7e-11
Identities = 43/120 (35%), Positives = 71/120 (59%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTL 504
L L+LS+N+LS+LP + +L L+ L + +NKL ALP + L L L++S+N +Q+L
Sbjct: 13 LTYLNLSRNQLSLLPPYICQLP-LRVLIVSNNKLGALPPDIGTLGSLRQLDVSSNELQSL 71
Query: 503 PVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVIELNL 324
P L L++L+ + N+L P++ LG L LD S N+++ IP L +++ L
Sbjct: 72 PSELCGLSSLRDLNVRRNQLSTLPEE-LGDLPLVRLDFSCNRVSRIPVSFCRLRHLQVIL 130
Score = 66.9 bits (156), Expect = 7e-11
Identities = 42/112 (37%), Positives = 61/112 (54%), Gaps = 1/112 (0%)
Frame = -2
Query: 695 LCDV-LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNN 519
+C + LR L +S NKL LP D+ L L+QL++ SN+LQ+LP L L L LN+ N
Sbjct: 30 ICQLPLRVLIVSNNKLGALPPDIGTLGSLRQLDVSSNELQSLPSELCGLSSLRDLNVRRN 89
Query: 518 FVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIP 363
+ TLP L +L L ++ S N++ P L+ L V+ L N + P
Sbjct: 90 QLSTLPEELGDL-PLVRLDFSCNRVSRIPVSFCRLRHLQVILLDSNPLQSPP 140
Score = 37.1 bits (82), Expect = 0.066
Identities = 19/49 (38%), Positives = 29/49 (59%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEV 537
L LD S N++S +P +L+HL+ + LDSN LQ+ P + KL +
Sbjct: 103 LVRLDFSCNRVSRIPVSFCRLRHLQVILLDSNPLQSPPAQVCLKGKLHI 151
>BC096326-1|AAH96326.1| 883|Homo sapiens LGR5 protein protein.
Length = 883
Score = 66.5 bits (155), Expect = 9e-11
Identities = 54/198 (27%), Positives = 99/198 (50%), Gaps = 12/198 (6%)
Frame = -2
Query: 734 DCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPD-DLSKLKHLKQLNLDSNKLQALPESLI 558
D L EIP+ F L+ + L+ NK+ +PD L L L+L +N++ +L +
Sbjct: 171 DNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCF 230
Query: 557 N-LKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQIL-GLQSLDVLDLS- 387
+ L LE L+++ N + P ++ L+NLK+++ +N +Q + L L L L+
Sbjct: 231 DGLHSLETLDLNYNNLDEFPTAIRTLSNLKELHFYDNPIQFVGRSAFQHLPELRTLTLNG 290
Query: 386 HNKITEIPYGMSELYVIELNLSQNEISLIGEDL-HQAPRLKILRLDENCLS-------LD 231
++ITE P + L L+ +IS + + + +Q P L++L L N L
Sbjct: 291 ASQITEFPDLTGTANLESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNLLEDLPSFSVCQ 350
Query: 230 EIKPSLLRDSKIHTVSVD 177
+++ LR ++I+ + VD
Sbjct: 351 KLQKIDLRHNEIYEIKVD 368
Score = 41.5 bits (93), Expect = 0.003
Identities = 38/120 (31%), Positives = 57/120 (47%), Gaps = 4/120 (3%)
Frame = -2
Query: 584 LQALPESLINLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPK-QILGLQS 408
L LP +L L++ NN Q LP L +L L+++ + N L PK GL S
Sbjct: 57 LSELPSNLSVFTSYLDLSM-NNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYS 115
Query: 407 LDVLDLSHNKITEIP-YGMSELYVIE-LNLSQNEISLIGEDLHQA-PRLKILRLDENCLS 237
L VL L +N++ +P + L ++ L L N IS + L+ L LD+N L+
Sbjct: 116 LKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALT 175
Score = 40.3 bits (90), Expect = 0.007
Identities = 27/89 (30%), Positives = 47/89 (52%), Gaps = 1/89 (1%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVL-PDDLSKLKHLKQLNLDSNKLQALPESLINL 552
++ EI +D F LR+L+L+ NK++++ P+ S L L +L+L SN L + P + L
Sbjct: 361 EIYEIKVDTFQQLLSLRSLNLAWNKIAIIHPNAFSTLPSLIKLDLSSNLLSSFP--ITGL 418
Query: 551 KKLEVLNISNNFVQTLPVCLKNLNNLKQV 465
L L ++ N + +N LK +
Sbjct: 419 HGLTHLKLTGNHALQSLISSENFPELKVI 447
>BC096325-1|AAH96325.1| 883|Homo sapiens LGR5 protein protein.
Length = 883
Score = 66.5 bits (155), Expect = 9e-11
Identities = 54/198 (27%), Positives = 99/198 (50%), Gaps = 12/198 (6%)
Frame = -2
Query: 734 DCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPD-DLSKLKHLKQLNLDSNKLQALPESLI 558
D L EIP+ F L+ + L+ NK+ +PD L L L+L +N++ +L +
Sbjct: 171 DNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCF 230
Query: 557 N-LKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQIL-GLQSLDVLDLS- 387
+ L LE L+++ N + P ++ L+NLK+++ +N +Q + L L L L+
Sbjct: 231 DGLHSLETLDLNYNNLDEFPTAIRTLSNLKELHFYDNPIQFVGRSAFQHLPELRTLTLNG 290
Query: 386 HNKITEIPYGMSELYVIELNLSQNEISLIGEDL-HQAPRLKILRLDENCLS-------LD 231
++ITE P + L L+ +IS + + + +Q P L++L L N L
Sbjct: 291 ASQITEFPDLTGTANLESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNLLEDLPSFSVCQ 350
Query: 230 EIKPSLLRDSKIHTVSVD 177
+++ LR ++I+ + VD
Sbjct: 351 KLQKIDLRHNEIYEIKVD 368
Score = 41.5 bits (93), Expect = 0.003
Identities = 38/120 (31%), Positives = 57/120 (47%), Gaps = 4/120 (3%)
Frame = -2
Query: 584 LQALPESLINLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPK-QILGLQS 408
L LP +L L++ NN Q LP L +L L+++ + N L PK GL S
Sbjct: 57 LSELPSNLSVFTSYLDLSM-NNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYS 115
Query: 407 LDVLDLSHNKITEIP-YGMSELYVIE-LNLSQNEISLIGEDLHQA-PRLKILRLDENCLS 237
L VL L +N++ +P + L ++ L L N IS + L+ L LD+N L+
Sbjct: 116 LKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALT 175
Score = 40.3 bits (90), Expect = 0.007
Identities = 27/89 (30%), Positives = 47/89 (52%), Gaps = 1/89 (1%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVL-PDDLSKLKHLKQLNLDSNKLQALPESLINL 552
++ EI +D F LR+L+L+ NK++++ P+ S L L +L+L SN L + P + L
Sbjct: 361 EIYEIKVDTFQQLLSLRSLNLAWNKIAIIHPNAFSTLPSLIKLDLSSNLLSSFP--ITGL 418
Query: 551 KKLEVLNISNNFVQTLPVCLKNLNNLKQV 465
L L ++ N + +N LK +
Sbjct: 419 HGLTHLKLTGNHALQSLISSENFPELKVI 447
>AL022344-3|CAI23616.1| 146|Homo sapiens novel protein similar to
Ras suppressor protein 1r 4 (tax-transcriptionally act
protein.
Length = 146
Score = 66.5 bits (155), Expect = 9e-11
Identities = 42/132 (31%), Positives = 70/132 (53%), Gaps = 4/132 (3%)
Frame = -2
Query: 575 LPESLINLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVL 396
+P ++ LK LEVLN NN ++ LP + L LK + N+L P+ L +L+VL
Sbjct: 1 VPPNIAELKNLEVLNFLNNQIEKLPTQISRLQKLKHLNLGMNRLNISPQGFGSLPALEVL 60
Query: 395 DLSHNKITE--IPYGMSELYVI-ELNLSQNEISLIGEDLHQAPRLKIL-RLDENCLSLDE 228
DL++N + E +P L + L LS N+ ++ D+ + +L+IL D N +SL +
Sbjct: 61 DLTYNNLNENYLPGNFFYLTTLCALYLSDNDFEILPPDIGKLTKLQILSNRDNNLISLPK 120
Query: 227 IKPSLLRDSKIH 192
L + ++H
Sbjct: 121 EIRVLTQLKELH 132
Score = 61.3 bits (142), Expect = 4e-09
Identities = 41/135 (30%), Positives = 69/135 (51%), Gaps = 3/135 (2%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNIS-NNFVQT 507
L L+ N++ LP +S+L+ LK LNL N+L P+ +L LEVL+++ NN +
Sbjct: 11 LEVLNFLNNQIEKLPTQISRLQKLKHLNLGMNRLNISPQGFGSLPALEVLDLTYNNLNEN 70
Query: 506 -LPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVI-E 333
LP L L +Y S+N + P I L L +L N + +P + L + E
Sbjct: 71 YLPGNFFYLTTLCALYLSDNDFEILPPDIGKLTKLQILSNRDNNLISLPKEIRVLTQLKE 130
Query: 332 LNLSQNEISLIGEDL 288
L++ N ++++ +L
Sbjct: 131 LHIQGNRLTVLPPEL 145
>BC129927-1|AAI29928.1| 1323|Homo sapiens PH domain and leucine rich
repeat protein phosphatase-like protein.
Length = 1323
Score = 65.7 bits (153), Expect = 2e-10
Identities = 35/85 (41%), Positives = 54/85 (63%), Gaps = 1/85 (1%)
Frame = -2
Query: 617 HLKQLNLDSNKLQALPESLIN-LKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQ 441
HL+ L+L +N+LQ P S +N L++LE LN+S N ++T+P + N L + A +N +
Sbjct: 645 HLRILHLANNQLQTFPASKLNKLEQLEELNLSGNKLKTIPTTIANCKRLHTLVAHSNNIS 704
Query: 440 AFPKQILGLQSLDVLDLSHNKITEI 366
FP +IL L + +DLS N +TEI
Sbjct: 705 IFP-EILQLPQIQFVDLSCNDLTEI 728
Score = 62.1 bits (144), Expect = 2e-09
Identities = 45/135 (33%), Positives = 67/135 (49%), Gaps = 4/135 (2%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSV-LP---DDLSKLKHLKQLNLDSNKLQALPESLI 558
L+E+P +F D+ L+L N + + P D L K LK LNL NKL P L
Sbjct: 261 LEEVPEHLFYSQDITY-LNLRHNFMQLERPGGLDTLYKFSQLKGLNLSHNKLGLFPILLC 319
Query: 557 NLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNK 378
+ L LN+S N LP + NL NL+ + N L P+++ LQ L L +S N
Sbjct: 320 EISTLTELNLSCNGFHDLPSQIGNLLNLQTLCLDGNFLTTLPEELGNLQQLSSLGISFNN 379
Query: 377 ITEIPYGMSELYVIE 333
++IP +L +++
Sbjct: 380 FSQIPEVYEKLTMLD 394
Score = 62.1 bits (144), Expect = 2e-09
Identities = 44/152 (28%), Positives = 75/152 (49%), Gaps = 3/152 (1%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTL 504
L+ L+LS NKL + P L ++ L +LNL N LP + NL L+ L + NF+ TL
Sbjct: 301 LKGLNLSHNKLGLFPILLCEISTLTELNLSCNGFHDLPSQIGNLLNLQTLCLDGNFLTTL 360
Query: 503 PVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSEL--YVIEL 330
P L NL L + S N P+ L LD + ++ N + + G+ ++ +
Sbjct: 361 PEELGNLQQLSSLGISFNNFSQIPEVYEKLTMLDRVVMAGNCLEVLNLGVLNRMNHIKHV 420
Query: 329 NLSQNEI-SLIGEDLHQAPRLKILRLDENCLS 237
+L N + +++ E+L + + L +N L+
Sbjct: 421 DLRMNHLKTMVIENLEGNKHITHVDLRDNRLT 452
Score = 56.8 bits (131), Expect = 8e-08
Identities = 52/209 (24%), Positives = 100/209 (47%), Gaps = 29/209 (13%)
Frame = -2
Query: 710 IDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLN 531
++V+ + +L LDLS+N L +PD + K ++ L++ N L +P +++ L L
Sbjct: 495 VNVYPVPSLLTFLDLSRNLLECVPDWACEAKKIEVLDVSYNLLTEVPVRILSSLSLRKLM 554
Query: 530 ISNNFVQTLPVCLKNLN-----------------------NLKQVYASNNKLQAFPKQIL 420
+ +N VQ LP ++++ NL+ + AS N L++ P
Sbjct: 555 LGHNHVQNLPTLVEHIPLEVLDLQHNALTRLPDTLFSKALNLRYLNASANSLESLPSACT 614
Query: 419 GLQSLDVLD---LSHNKITE--IPYGMSELYVIELNLSQNEISLI-GEDLHQAPRLKILR 258
G +SL +L L++N +T+ IP + L++ L+L+ N++ L++ +L+ L
Sbjct: 615 GEESLSMLQLLYLTNNLLTDQCIPVLVGHLHLRILHLANNQLQTFPASKLNKLEQLEELN 674
Query: 257 LDENCLSLDEIKPSLLRDSKIHTVSVDGN 171
L N L I ++ ++HT+ N
Sbjct: 675 LSGN--KLKTIPTTIANCKRLHTLVAHSN 701
Score = 56.0 bits (129), Expect = 1e-07
Identities = 52/188 (27%), Positives = 86/188 (45%), Gaps = 5/188 (2%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQ-ALP---ESLINLKKLEVLNISNNF 516
+ +DLS L +P+ L + + LNL N +Q P ++L +L+ LN+S+N
Sbjct: 251 ISTVDLSCYSLEEVPEHLFYSQDITYLNLRHNFMQLERPGGLDTLYKFSQLKGLNLSHNK 310
Query: 515 VQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVI 336
+ P+ L ++ L ++ S N P QI L +L L L N +T +P + L +
Sbjct: 311 LGLFPILLCEISTLTELNLSCNGFHDLPSQIGNLLNLQTLCLDGNFLTTLPEELGNLQQL 370
Query: 335 -ELNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIHTVSVDGNLFEP 159
L +S N S I E + L + + NCL + + L R + I V + N +
Sbjct: 371 SSLGISFNNFSQIPEVYEKLTMLDRVVMAGNCLEVLNL-GVLNRMNHIKHVDLRMNHLKT 429
Query: 158 KQLAXLEG 135
+ LEG
Sbjct: 430 MVIENLEG 437
Score = 54.4 bits (125), Expect = 4e-07
Identities = 46/148 (31%), Positives = 72/148 (48%), Gaps = 6/148 (4%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLS---KLKHLKQLNLDSNKL--QALPESL 561
L +P +FS LR L+ S N L LP + L L+ L L +N L Q +P L
Sbjct: 582 LTRLPDTLFSKALNLRYLNASANSLESLPSACTGEESLSMLQLLYLTNNLLTDQCIPV-L 640
Query: 560 INLKKLEVLNISNNFVQTLPVC-LKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSH 384
+ L +L+++NN +QT P L L L+++ S NKL+ P I + L L
Sbjct: 641 VGHLHLRILHLANNQLQTFPASKLNKLEQLEELNLSGNKLKTIPTTIANCKRLHTLVAHS 700
Query: 383 NKITEIPYGMSELYVIELNLSQNEISLI 300
N I+ P + + ++LS N+++ I
Sbjct: 701 NNISIFPEILQLPQIQFVDLSCNDLTEI 728
Score = 48.8 bits (111), Expect = 2e-05
Identities = 46/170 (27%), Positives = 80/170 (47%), Gaps = 6/170 (3%)
Frame = -2
Query: 620 KHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQ-TLPVCLKNL---NNLKQVYASN 453
+ + ++L L+ +PE L + + LN+ +NF+Q P L L + LK + S+
Sbjct: 249 QRISTVDLSCYSLEEVPEHLFYSQDITYLNLRHNFMQLERPGGLDTLYKFSQLKGLNLSH 308
Query: 452 NKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVIE-LNLSQNEISLIGEDLHQAP 276
NKL FP + + +L L+LS N ++P + L ++ L L N ++ + E+L
Sbjct: 309 NKLGLFPILLCEISTLTELNLSCNGFHDLPSQIGNLLNLQTLCLDGNFLTTLPEELGNLQ 368
Query: 275 RLKILRLDENCLS-LDEIKPSLLRDSKIHTVSVDGNLFEPKQLAXLEGYN 129
+L L + N S + E+ L + + V + GN E L L N
Sbjct: 369 QLSSLGISFNNFSQIPEVYEKL---TMLDRVVMAGNCLEVLNLGVLNRMN 415
Score = 40.3 bits (90), Expect = 0.007
Identities = 21/74 (28%), Positives = 40/74 (54%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESL 561
+A+ +L+ P + + L L+LS NKL +P ++ K L L SN + PE +
Sbjct: 651 LANNQLQTFPASKLNKLEQLEELNLSGNKLKTIPTTIANCKRLHTLVAHSNNISIFPE-I 709
Query: 560 INLKKLEVLNISNN 519
+ L +++ +++S N
Sbjct: 710 LQLPQIQFVDLSCN 723
>BC035267-1|AAH35267.1| 723|Homo sapiens PHLPPL protein protein.
Length = 723
Score = 65.3 bits (152), Expect = 2e-10
Identities = 35/85 (41%), Positives = 53/85 (62%), Gaps = 1/85 (1%)
Frame = -2
Query: 617 HLKQLNLDSNKLQALPESLIN-LKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQ 441
HL+ L L +N+LQ P S +N L++LE LN+S N ++T+P + N L + A +N +
Sbjct: 383 HLRILRLANNQLQTFPASKLNKLEQLEELNLSGNKLKTIPTTIANCKRLHTLVAHSNNIS 442
Query: 440 AFPKQILGLQSLDVLDLSHNKITEI 366
FP +IL L + +DLS N +TEI
Sbjct: 443 IFP-EILQLPQIQFVDLSCNDLTEI 466
Score = 62.1 bits (144), Expect = 2e-09
Identities = 44/152 (28%), Positives = 75/152 (49%), Gaps = 3/152 (1%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTL 504
L+ L+LS NKL + P L ++ L +LNL N LP + NL L+ L + NF+ TL
Sbjct: 39 LKGLNLSHNKLGLFPILLCEISTLTELNLSCNGFHDLPSQIGNLLNLQTLCLDGNFLTTL 98
Query: 503 PVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSEL--YVIEL 330
P L NL L + S N P+ L LD + ++ N + + G+ ++ +
Sbjct: 99 PEELGNLQQLSSLGISFNNFSQIPEVYEKLTMLDRVVMAGNCLEVLNLGVLNRMNHIKHV 158
Query: 329 NLSQNEI-SLIGEDLHQAPRLKILRLDENCLS 237
+L N + +++ E+L + + L +N L+
Sbjct: 159 DLRMNHLKTMVIENLEGNKHITHVDLRDNRLT 190
Score = 60.9 bits (141), Expect = 5e-09
Identities = 36/102 (35%), Positives = 51/102 (50%)
Frame = -2
Query: 638 DDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYA 459
D L K LK LNL NKL P L + L LN+S N LP + NL NL+ +
Sbjct: 31 DTLYKFSQLKGLNLSHNKLGLFPILLCEISTLTELNLSCNGFHDLPSQIGNLLNLQTLCL 90
Query: 458 SNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVIE 333
N L P+++ LQ L L +S N ++IP +L +++
Sbjct: 91 DGNFLTTLPEELGNLQQLSSLGISFNNFSQIPEVYEKLTMLD 132
Score = 56.4 bits (130), Expect = 1e-07
Identities = 52/209 (24%), Positives = 99/209 (47%), Gaps = 29/209 (13%)
Frame = -2
Query: 710 IDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLN 531
++V+ + +L LDLS+N L +PD + K ++ L++ N L +P +++ L L
Sbjct: 233 VNVYPVPSLLTFLDLSRNLLECVPDWACEAKKIEVLDVSYNLLTEVPVRILSSLSLRKLM 292
Query: 530 ISNNFVQTLPVCLKNLN-----------------------NLKQVYASNNKLQAFPKQIL 420
+ +N VQ LP ++++ NL+ + AS N L++ P
Sbjct: 293 LGHNHVQNLPTLVEHIPLEVLDLQHNALTRLPDTLFSKALNLRYLNASANSLESLPSACT 352
Query: 419 GLQSLDVLD---LSHNKITE--IPYGMSELYVIELNLSQNEISLI-GEDLHQAPRLKILR 258
G +SL +L L++N +T+ IP + L++ L L+ N++ L++ +L+ L
Sbjct: 353 GEESLSMLQLLYLTNNLLTDQCIPVLVGHLHLRILRLANNQLQTFPASKLNKLEQLEELN 412
Query: 257 LDENCLSLDEIKPSLLRDSKIHTVSVDGN 171
L N L I ++ ++HT+ N
Sbjct: 413 LSGN--KLKTIPTTIANCKRLHTLVAHSN 439
Score = 54.0 bits (124), Expect = 5e-07
Identities = 46/148 (31%), Positives = 71/148 (47%), Gaps = 6/148 (4%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLS---KLKHLKQLNLDSNKL--QALPESL 561
L +P +FS LR L+ S N L LP + L L+ L L +N L Q +P L
Sbjct: 320 LTRLPDTLFSKALNLRYLNASANSLESLPSACTGEESLSMLQLLYLTNNLLTDQCIPV-L 378
Query: 560 INLKKLEVLNISNNFVQTLPVC-LKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSH 384
+ L +L ++NN +QT P L L L+++ S NKL+ P I + L L
Sbjct: 379 VGHLHLRILRLANNQLQTFPASKLNKLEQLEELNLSGNKLKTIPTTIANCKRLHTLVAHS 438
Query: 383 NKITEIPYGMSELYVIELNLSQNEISLI 300
N I+ P + + ++LS N+++ I
Sbjct: 439 NNISIFPEILQLPQIQFVDLSCNDLTEI 466
Score = 44.8 bits (101), Expect = 3e-04
Identities = 44/155 (28%), Positives = 73/155 (47%), Gaps = 6/155 (3%)
Frame = -2
Query: 575 LPESLINLKKLEVLNISNNFVQ-TLPVCLKNL---NNLKQVYASNNKLQAFPKQILGLQS 408
+PE L + + LN+ +NF+Q P L L + LK + S+NKL FP + + +
Sbjct: 2 VPEHLFYSQDITYLNLRHNFMQLERPGGLDTLYKFSQLKGLNLSHNKLGLFPILLCEIST 61
Query: 407 LDVLDLSHNKITEIPYGMSELYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDENCLS-L 234
L L+LS N ++P + L ++ L L N ++ + E+L +L L + N S +
Sbjct: 62 LTELNLSCNGFHDLPSQIGNLLNLQTLCLDGNFLTTLPEELGNLQQLSSLGISFNNFSQI 121
Query: 233 DEIKPSLLRDSKIHTVSVDGNLFEPKQLAXLEGYN 129
E+ L + + V + GN E L L N
Sbjct: 122 PEVYEKL---TMLDRVVMAGNCLEVLNLGVLNRMN 153
Score = 40.3 bits (90), Expect = 0.007
Identities = 21/74 (28%), Positives = 40/74 (54%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESL 561
+A+ +L+ P + + L L+LS NKL +P ++ K L L SN + PE +
Sbjct: 389 LANNQLQTFPASKLNKLEQLEELNLSGNKLKTIPTTIANCKRLHTLVAHSNNISIFPE-I 447
Query: 560 INLKKLEVLNISNN 519
+ L +++ +++S N
Sbjct: 448 LQLPQIQFVDLSCN 461
>BC099650-1|AAH99650.1| 907|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 5 protein.
Length = 907
Score = 64.5 bits (150), Expect = 4e-10
Identities = 44/150 (29%), Positives = 77/150 (51%), Gaps = 5/150 (3%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDD-LSKLKHLKQLNLDSNKLQALP-ESLIN 555
+L+ +P + L++L L N +S +P S L L+ L LD N L +P ++ +
Sbjct: 125 QLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRS 184
Query: 554 LKKLEVLNISNNFVQTLP-VCLKNLNNLKQVYASNNKLQAFPKQIL-GLQSLDVLDLSHN 381
L L+ + ++ N + +P NL++L ++ NN++ + K+ GL SL+ LDL++N
Sbjct: 185 LSALQAMTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYN 244
Query: 380 KITEIPYGMSELYVI-ELNLSQNEISLIGE 294
+ E P + L + EL N I I E
Sbjct: 245 NLDEFPTAIRTLSNLKELGFHSNNIRSIPE 274
Score = 58.0 bits (134), Expect = 3e-08
Identities = 36/123 (29%), Positives = 64/123 (52%), Gaps = 3/123 (2%)
Frame = -2
Query: 734 DCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPD-DLSKLKHLKQLNLDSNKLQALPESLI 558
D L EIP+ F L+ + L+ NK+ +PD L L L+L +N++ +L +
Sbjct: 171 DNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCF 230
Query: 557 N-LKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFP-KQILGLQSLDVLDLSH 384
+ L LE L+++ N + P ++ L+NLK++ +N +++ P K +G SL +
Sbjct: 231 DGLHSLETLDLNYNNLDEFPTAIRTLSNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYD 290
Query: 383 NKI 375
N I
Sbjct: 291 NPI 293
Score = 41.5 bits (93), Expect = 0.003
Identities = 38/120 (31%), Positives = 57/120 (47%), Gaps = 4/120 (3%)
Frame = -2
Query: 584 LQALPESLINLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPK-QILGLQS 408
L LP +L L++ NN Q LP L +L L+++ + N L PK GL S
Sbjct: 57 LSELPSNLSVFTSYLDLSM-NNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYS 115
Query: 407 LDVLDLSHNKITEIP-YGMSELYVIE-LNLSQNEISLIGEDLHQA-PRLKILRLDENCLS 237
L VL L +N++ +P + L ++ L L N IS + L+ L LD+N L+
Sbjct: 116 LKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALT 175
Score = 41.1 bits (92), Expect = 0.004
Identities = 28/110 (25%), Positives = 58/110 (52%), Gaps = 3/110 (2%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPE-SLINLKKLEVLNISNNFVQT 507
L LDL+ N L P + L +LK+L SN ++++PE + + L ++ +N +Q
Sbjct: 236 LETLDLNYNNLDEFPTAIRTLSNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPIQF 295
Query: 506 L-PVCLKNLNNLKQVYASN-NKLQAFPKQILGLQSLDVLDLSHNKITEIP 363
+ ++L L+ + + +++ FP + G +L+ L L+ +I+ +P
Sbjct: 296 VGRSAFQHLPELRTLTLNGASQITEFP-DLTGTANLESLTLTGAQISSLP 344
Score = 40.3 bits (90), Expect = 0.007
Identities = 27/89 (30%), Positives = 47/89 (52%), Gaps = 1/89 (1%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVL-PDDLSKLKHLKQLNLDSNKLQALPESLINL 552
++ EI +D F LR+L+L+ NK++++ P+ S L L +L+L SN L + P + L
Sbjct: 385 EIYEIKVDTFQQLLSLRSLNLAWNKIAIIHPNAFSTLPSLIKLDLSSNLLSSFP--ITGL 442
Query: 551 KKLEVLNISNNFVQTLPVCLKNLNNLKQV 465
L L ++ N + +N LK +
Sbjct: 443 HGLTHLKLTGNHALQSLISSENFPELKVI 471
>BC096324-1|AAH96324.1| 907|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 5 protein.
Length = 907
Score = 64.5 bits (150), Expect = 4e-10
Identities = 44/150 (29%), Positives = 77/150 (51%), Gaps = 5/150 (3%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDD-LSKLKHLKQLNLDSNKLQALP-ESLIN 555
+L+ +P + L++L L N +S +P S L L+ L LD N L +P ++ +
Sbjct: 125 QLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRS 184
Query: 554 LKKLEVLNISNNFVQTLP-VCLKNLNNLKQVYASNNKLQAFPKQIL-GLQSLDVLDLSHN 381
L L+ + ++ N + +P NL++L ++ NN++ + K+ GL SL+ LDL++N
Sbjct: 185 LSALQAMTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYN 244
Query: 380 KITEIPYGMSELYVI-ELNLSQNEISLIGE 294
+ E P + L + EL N I I E
Sbjct: 245 NLDEFPTAIRTLSNLKELGFHSNNIRSIPE 274
Score = 58.0 bits (134), Expect = 3e-08
Identities = 36/123 (29%), Positives = 64/123 (52%), Gaps = 3/123 (2%)
Frame = -2
Query: 734 DCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPD-DLSKLKHLKQLNLDSNKLQALPESLI 558
D L EIP+ F L+ + L+ NK+ +PD L L L+L +N++ +L +
Sbjct: 171 DNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCF 230
Query: 557 N-LKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFP-KQILGLQSLDVLDLSH 384
+ L LE L+++ N + P ++ L+NLK++ +N +++ P K +G SL +
Sbjct: 231 DGLHSLETLDLNYNNLDEFPTAIRTLSNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYD 290
Query: 383 NKI 375
N I
Sbjct: 291 NPI 293
Score = 41.5 bits (93), Expect = 0.003
Identities = 38/120 (31%), Positives = 57/120 (47%), Gaps = 4/120 (3%)
Frame = -2
Query: 584 LQALPESLINLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPK-QILGLQS 408
L LP +L L++ NN Q LP L +L L+++ + N L PK GL S
Sbjct: 57 LSELPSNLSVFTSYLDLSM-NNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYS 115
Query: 407 LDVLDLSHNKITEIP-YGMSELYVIE-LNLSQNEISLIGEDLHQA-PRLKILRLDENCLS 237
L VL L +N++ +P + L ++ L L N IS + L+ L LD+N L+
Sbjct: 116 LKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALT 175
Score = 41.1 bits (92), Expect = 0.004
Identities = 28/110 (25%), Positives = 58/110 (52%), Gaps = 3/110 (2%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPE-SLINLKKLEVLNISNNFVQT 507
L LDL+ N L P + L +LK+L SN ++++PE + + L ++ +N +Q
Sbjct: 236 LETLDLNYNNLDEFPTAIRTLSNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPIQF 295
Query: 506 L-PVCLKNLNNLKQVYASN-NKLQAFPKQILGLQSLDVLDLSHNKITEIP 363
+ ++L L+ + + +++ FP + G +L+ L L+ +I+ +P
Sbjct: 296 VGRSAFQHLPELRTLTLNGASQITEFP-DLTGTANLESLTLTGAQISSLP 344
Score = 40.3 bits (90), Expect = 0.007
Identities = 27/89 (30%), Positives = 47/89 (52%), Gaps = 1/89 (1%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVL-PDDLSKLKHLKQLNLDSNKLQALPESLINL 552
++ EI +D F LR+L+L+ NK++++ P+ S L L +L+L SN L + P + L
Sbjct: 385 EIYEIKVDTFQQLLSLRSLNLAWNKIAIIHPNAFSTLPSLIKLDLSSNLLSSFP--ITGL 442
Query: 551 KKLEVLNISNNFVQTLPVCLKNLNNLKQV 465
L L ++ N + +N LK +
Sbjct: 443 HGLTHLKLTGNHALQSLISSENFPELKVI 471
>AF062006-1|AAC28019.1| 907|Homo sapiens orphan G protein-coupled
receptor HG38 protein.
Length = 907
Score = 64.5 bits (150), Expect = 4e-10
Identities = 44/150 (29%), Positives = 77/150 (51%), Gaps = 5/150 (3%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDD-LSKLKHLKQLNLDSNKLQALP-ESLIN 555
+L+ +P + L++L L N +S +P S L L+ L LD N L +P ++ +
Sbjct: 125 QLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRS 184
Query: 554 LKKLEVLNISNNFVQTLP-VCLKNLNNLKQVYASNNKLQAFPKQIL-GLQSLDVLDLSHN 381
L L+ + ++ N + +P NL++L ++ NN++ + K+ GL SL+ LDL++N
Sbjct: 185 LSALQAMTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYN 244
Query: 380 KITEIPYGMSELYVI-ELNLSQNEISLIGE 294
+ E P + L + EL N I I E
Sbjct: 245 NLDEFPTAIRTLSNLKELGFHSNNIRSIPE 274
Score = 58.0 bits (134), Expect = 3e-08
Identities = 36/123 (29%), Positives = 64/123 (52%), Gaps = 3/123 (2%)
Frame = -2
Query: 734 DCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPD-DLSKLKHLKQLNLDSNKLQALPESLI 558
D L EIP+ F L+ + L+ NK+ +PD L L L+L +N++ +L +
Sbjct: 171 DNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCF 230
Query: 557 N-LKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFP-KQILGLQSLDVLDLSH 384
+ L LE L+++ N + P ++ L+NLK++ +N +++ P K +G SL +
Sbjct: 231 DGLHSLETLDLNYNNLDEFPTAIRTLSNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYD 290
Query: 383 NKI 375
N I
Sbjct: 291 NPI 293
Score = 41.5 bits (93), Expect = 0.003
Identities = 38/120 (31%), Positives = 57/120 (47%), Gaps = 4/120 (3%)
Frame = -2
Query: 584 LQALPESLINLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPK-QILGLQS 408
L LP +L L++ NN Q LP L +L L+++ + N L PK GL S
Sbjct: 57 LSELPSNLSVFTSYLDLSM-NNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYS 115
Query: 407 LDVLDLSHNKITEIP-YGMSELYVIE-LNLSQNEISLIGEDLHQA-PRLKILRLDENCLS 237
L VL L +N++ +P + L ++ L L N IS + L+ L LD+N L+
Sbjct: 116 LKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALT 175
Score = 41.1 bits (92), Expect = 0.004
Identities = 28/110 (25%), Positives = 58/110 (52%), Gaps = 3/110 (2%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPE-SLINLKKLEVLNISNNFVQT 507
L LDL+ N L P + L +LK+L SN ++++PE + + L ++ +N +Q
Sbjct: 236 LETLDLNYNNLDEFPTAIRTLSNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPIQF 295
Query: 506 L-PVCLKNLNNLKQVYASN-NKLQAFPKQILGLQSLDVLDLSHNKITEIP 363
+ ++L L+ + + +++ FP + G +L+ L L+ +I+ +P
Sbjct: 296 VGRSAFQHLPELRTLTLNGASQITEFP-DLTGTANLESLTLTGAQISSLP 344
Score = 40.3 bits (90), Expect = 0.007
Identities = 27/89 (30%), Positives = 47/89 (52%), Gaps = 1/89 (1%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVL-PDDLSKLKHLKQLNLDSNKLQALPESLINL 552
++ EI +D F LR+L+L+ NK++++ P+ S L L +L+L SN L + P + L
Sbjct: 385 EIYEIKVDTFQQLLSLRSLNLAWNKIAIIHPNAFSTLPSLIKLDLSSNLLSSFP--ITGL 442
Query: 551 KKLEVLNISNNFVQTLPVCLKNLNNLKQV 465
L L ++ N + +N LK +
Sbjct: 443 HGLTHLKLTGNHALQSLISSENFPELKVI 471
>AB071037-1|BAB84587.1| 581|Homo sapiens Lib protein.
Length = 581
Score = 64.1 bits (149), Expect = 5e-10
Identities = 60/194 (30%), Positives = 96/194 (49%), Gaps = 8/194 (4%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSK-LKHLKQLNLDSNK-LQALPESLIN 555
+L I F LR L L+ NKL VLP L + L L+ L L SN+ LQ P
Sbjct: 88 ELSRITPGAFRNLGSLRYLSLANNKLQVLPIGLFQGLDSLESLLLSSNQLLQIQPAHFSQ 147
Query: 554 LKKLEVLNISNNFVQTLP-VCLKNLNNLKQVYASNNKL-QAFPKQILGLQSLDVLDLSHN 381
L+ L + N ++ +P +L L ++ N L P+ L +L VL L N
Sbjct: 148 CSNLKELQLHGNHLEYIPDGAFDHLVGLTKLNLGKNSLTHISPRVFQHLGNLQVLRLYEN 207
Query: 380 KITEIPYGMSE--LYVIELNLSQNEISLIGEDL-HQAPRLKILRLDENCLSLDEIKPSL- 213
++T+IP G + + + EL L QN+I L+ L H L+ L L N +S ++ PS+
Sbjct: 208 RLTDIPMGTFDGLVNLQELALQQNQIGLLSPGLFHNNHNLQRLYLSNNHIS--QLPPSIF 265
Query: 212 LRDSKIHTVSVDGN 171
++ +++ +++ GN
Sbjct: 266 MQLPQLNRLTLFGN 279
Score = 57.2 bits (132), Expect = 6e-08
Identities = 39/128 (30%), Positives = 67/128 (52%), Gaps = 4/128 (3%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDL-SKLKHLKQLNLDSNKLQAL-PESLINL 552
LKE+ + +F LR L L N +S LPD++ S L+ L+ L L N++ + P + L
Sbjct: 281 LKELSLGIFGPMPNLRELWLYDNHISSLPDNVFSNLRQLQVLILSRNQISFISPGAFNGL 340
Query: 551 KKLEVLNISNNFVQTLP-VCLKNLNNLKQVYASNNKLQAFPKQIL-GLQSLDVLDLSHNK 378
+L L++ N +Q L + L NL+ + NN+L+ P I + L + L +N+
Sbjct: 341 TELRELSLHTNALQDLDGNVFRMLANLQNISLQNNRLRQLPGNIFANVNGLMAIQLQNNQ 400
Query: 377 ITEIPYGM 354
+ +P G+
Sbjct: 401 LENLPLGI 408
Score = 50.8 bits (116), Expect = 5e-06
Identities = 33/104 (31%), Positives = 58/104 (55%), Gaps = 3/104 (2%)
Frame = -2
Query: 734 DCKLKEIPIDVFSLCDVLRNLDLSKNKLS-VLPDDLSKLKHLKQLNLDSNKLQALPESLI 558
D + +P +VFS L+ L LS+N++S + P + L L++L+L +N LQ L ++
Sbjct: 302 DNHISSLPDNVFSNLRQLQVLILSRNQISFISPGAFNGLTELRELSLHTNALQDLDGNVF 361
Query: 557 N-LKKLEVLNISNNFVQTLP-VCLKNLNNLKQVYASNNKLQAFP 432
L L+ +++ NN ++ LP N+N L + NN+L+ P
Sbjct: 362 RMLANLQNISLQNNRLRQLPGNIFANVNGLMAIQLQNNQLENLP 405
Score = 44.8 bits (101), Expect = 3e-04
Identities = 44/141 (31%), Positives = 67/141 (47%), Gaps = 5/141 (3%)
Frame = -2
Query: 614 LKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTL-PVCLKNLNNLKQVYASNNKLQA 438
L+ LN +L P +N+ L L I N + + P +NL +L+ + +NNKLQ
Sbjct: 58 LQILNTHITELNESP--FLNISALIALRIEKNELSRITPGAFRNLGSLRYLSLANNKLQV 115
Query: 437 FPKQIL-GLQSLDVLDLSHNKITEI-PYGMSELYVI-ELNLSQNEISLIGED-LHQAPRL 270
P + GL SL+ L LS N++ +I P S+ + EL L N + I + L
Sbjct: 116 LPIGLFQGLDSLESLLLSSNQLLQIQPAHFSQCSNLKELQLHGNHLEYIPDGAFDHLVGL 175
Query: 269 KILRLDENCLSLDEIKPSLLR 207
L L +N SL I P + +
Sbjct: 176 TKLNLGKN--SLTHISPRVFQ 194
>BC101065-1|AAI01066.1| 581|Homo sapiens LRRC15 protein protein.
Length = 581
Score = 63.7 bits (148), Expect = 7e-10
Identities = 60/194 (30%), Positives = 96/194 (49%), Gaps = 8/194 (4%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSK-LKHLKQLNLDSNK-LQALPESLIN 555
+L I F LR L L+ NKL VLP L + L L+ L L SN+ LQ P
Sbjct: 88 ELSRITPGAFRNLGSLRYLSLANNKLQVLPIGLFQGLDSLESLLLSSNQLLQIQPAHFSQ 147
Query: 554 LKKLEVLNISNNFVQTLP-VCLKNLNNLKQVYASNNKL-QAFPKQILGLQSLDVLDLSHN 381
L+ L + N ++ +P +L L ++ N L P+ L +L VL L N
Sbjct: 148 CSNLKELQLHGNHLEYIPDGAFDHLVGLTKLNLGKNSLTHISPRVFQHLGNLQVLRLYEN 207
Query: 380 KITEIPYGMSE--LYVIELNLSQNEISLIGEDL-HQAPRLKILRLDENCLSLDEIKPSL- 213
++T+IP G + + + EL L QN+I L+ L H L+ L L N +S ++ PS+
Sbjct: 208 RLTDIPMGTFDGLVNLQELALQQNQIGLLSPGLFHNNHNLQRLYLSNNHIS--QLPPSVF 265
Query: 212 LRDSKIHTVSVDGN 171
++ +++ +++ GN
Sbjct: 266 MQLPQLNRLTLFGN 279
Score = 55.2 bits (127), Expect = 2e-07
Identities = 39/128 (30%), Positives = 66/128 (51%), Gaps = 4/128 (3%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDL-SKLKHLKQLNLDSNKLQAL-PESLINL 552
LKE+ +F LR L L N +S LPD++ S L+ L+ L L N++ + P + L
Sbjct: 281 LKELSPGIFGPMPNLRELWLYDNHISSLPDNVFSNLRQLQVLILSRNQISFISPGAFNGL 340
Query: 551 KKLEVLNISNNFVQTLP-VCLKNLNNLKQVYASNNKLQAFPKQIL-GLQSLDVLDLSHNK 378
+L L++ N +Q L + L NL+ + NN+L+ P I + L + L +N+
Sbjct: 341 TELRELSLHTNALQDLDGNVFRMLANLQNISLQNNRLRQLPGNIFANVNGLMAIQLQNNQ 400
Query: 377 ITEIPYGM 354
+ +P G+
Sbjct: 401 LENLPLGI 408
Score = 50.8 bits (116), Expect = 5e-06
Identities = 33/104 (31%), Positives = 58/104 (55%), Gaps = 3/104 (2%)
Frame = -2
Query: 734 DCKLKEIPIDVFSLCDVLRNLDLSKNKLS-VLPDDLSKLKHLKQLNLDSNKLQALPESLI 558
D + +P +VFS L+ L LS+N++S + P + L L++L+L +N LQ L ++
Sbjct: 302 DNHISSLPDNVFSNLRQLQVLILSRNQISFISPGAFNGLTELRELSLHTNALQDLDGNVF 361
Query: 557 N-LKKLEVLNISNNFVQTLP-VCLKNLNNLKQVYASNNKLQAFP 432
L L+ +++ NN ++ LP N+N L + NN+L+ P
Sbjct: 362 RMLANLQNISLQNNRLRQLPGNIFANVNGLMAIQLQNNQLENLP 405
Score = 44.8 bits (101), Expect = 3e-04
Identities = 44/141 (31%), Positives = 67/141 (47%), Gaps = 5/141 (3%)
Frame = -2
Query: 614 LKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTL-PVCLKNLNNLKQVYASNNKLQA 438
L+ LN +L P +N+ L L I N + + P +NL +L+ + +NNKLQ
Sbjct: 58 LQILNTHITELNESP--FLNISALIALRIEKNELSRITPGAFRNLGSLRYLSLANNKLQV 115
Query: 437 FPKQIL-GLQSLDVLDLSHNKITEI-PYGMSELYVI-ELNLSQNEISLIGED-LHQAPRL 270
P + GL SL+ L LS N++ +I P S+ + EL L N + I + L
Sbjct: 116 LPIGLFQGLDSLESLLLSSNQLLQIQPAHFSQCSNLKELQLHGNHLEYIPDGAFDHLVGL 175
Query: 269 KILRLDENCLSLDEIKPSLLR 207
L L +N SL I P + +
Sbjct: 176 TKLNLGKN--SLTHISPRVFQ 194
>BC101064-1|AAI01065.1| 581|Homo sapiens leucine rich repeat
containing 15 protein.
Length = 581
Score = 63.7 bits (148), Expect = 7e-10
Identities = 60/194 (30%), Positives = 96/194 (49%), Gaps = 8/194 (4%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSK-LKHLKQLNLDSNK-LQALPESLIN 555
+L I F LR L L+ NKL VLP L + L L+ L L SN+ LQ P
Sbjct: 88 ELSRITPGAFRNLGSLRYLSLANNKLQVLPIGLFQGLDSLESLLLSSNQLLQIQPAHFSQ 147
Query: 554 LKKLEVLNISNNFVQTLP-VCLKNLNNLKQVYASNNKL-QAFPKQILGLQSLDVLDLSHN 381
L+ L + N ++ +P +L L ++ N L P+ L +L VL L N
Sbjct: 148 CSNLKELQLHGNHLEYIPDGAFDHLVGLTKLNLGKNSLTHISPRVFQHLGNLQVLRLYEN 207
Query: 380 KITEIPYGMSE--LYVIELNLSQNEISLIGEDL-HQAPRLKILRLDENCLSLDEIKPSL- 213
++T+IP G + + + EL L QN+I L+ L H L+ L L N +S ++ PS+
Sbjct: 208 RLTDIPMGTFDGLVNLQELALQQNQIGLLSPGLFHNNHNLQRLYLSNNHIS--QLPPSVF 265
Query: 212 LRDSKIHTVSVDGN 171
++ +++ +++ GN
Sbjct: 266 MQLPQLNRLTLFGN 279
Score = 55.2 bits (127), Expect = 2e-07
Identities = 39/128 (30%), Positives = 66/128 (51%), Gaps = 4/128 (3%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDL-SKLKHLKQLNLDSNKLQAL-PESLINL 552
LKE+ +F LR L L N +S LPD++ S L+ L+ L L N++ + P + L
Sbjct: 281 LKELSPGIFGPMPNLRELWLYDNHISSLPDNVFSNLRQLQVLILSRNQISFISPGAFNGL 340
Query: 551 KKLEVLNISNNFVQTLP-VCLKNLNNLKQVYASNNKLQAFPKQIL-GLQSLDVLDLSHNK 378
+L L++ N +Q L + L NL+ + NN+L+ P I + L + L +N+
Sbjct: 341 TELRELSLHTNALQDLDGNVFRMLANLQNISLQNNRLRQLPGNIFANVNGLMAIQLQNNQ 400
Query: 377 ITEIPYGM 354
+ +P G+
Sbjct: 401 LENLPLGI 408
Score = 50.8 bits (116), Expect = 5e-06
Identities = 33/104 (31%), Positives = 58/104 (55%), Gaps = 3/104 (2%)
Frame = -2
Query: 734 DCKLKEIPIDVFSLCDVLRNLDLSKNKLS-VLPDDLSKLKHLKQLNLDSNKLQALPESLI 558
D + +P +VFS L+ L LS+N++S + P + L L++L+L +N LQ L ++
Sbjct: 302 DNHISSLPDNVFSNLRQLQVLILSRNQISFISPGAFNGLTELRELSLHTNALQDLDGNVF 361
Query: 557 N-LKKLEVLNISNNFVQTLP-VCLKNLNNLKQVYASNNKLQAFP 432
L L+ +++ NN ++ LP N+N L + NN+L+ P
Sbjct: 362 RMLANLQNISLQNNRLRQLPGNIFANVNGLMAIQLQNNQLENLP 405
Score = 44.8 bits (101), Expect = 3e-04
Identities = 44/141 (31%), Positives = 67/141 (47%), Gaps = 5/141 (3%)
Frame = -2
Query: 614 LKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTL-PVCLKNLNNLKQVYASNNKLQA 438
L+ LN +L P +N+ L L I N + + P +NL +L+ + +NNKLQ
Sbjct: 58 LQILNTHITELNESP--FLNISALIALRIEKNELSRITPGAFRNLGSLRYLSLANNKLQV 115
Query: 437 FPKQIL-GLQSLDVLDLSHNKITEI-PYGMSELYVI-ELNLSQNEISLIGED-LHQAPRL 270
P + GL SL+ L LS N++ +I P S+ + EL L N + I + L
Sbjct: 116 LPIGLFQGLDSLESLLLSSNQLLQIQPAHFSQCSNLKELQLHGNHLEYIPDGAFDHLVGL 175
Query: 269 KILRLDENCLSLDEIKPSLLR 207
L L +N SL I P + +
Sbjct: 176 TKLNLGKN--SLTHISPRVFQ 194
>BC046356-1|AAH46356.1| 421|Homo sapiens osteomodulin protein.
Length = 421
Score = 62.5 bits (145), Expect = 2e-09
Identities = 50/158 (31%), Positives = 84/158 (53%), Gaps = 10/158 (6%)
Frame = -2
Query: 683 LRNLDLSKNKL--SVLPDDL-SKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFV 513
L LDL N L S+L D + +K++ L QLNL SN+L+++P L + L L++ NN +
Sbjct: 188 LTMLDLCYNYLHDSLLKDKIFAKMEKLMQLNLCSNRLESMPPGLPS--SLMYLSLENNSI 245
Query: 512 QTLPV-CLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITE---IPYGMSEL 345
++P L L + S+NKLQ P I L ++ L + HNK+ + IP + L
Sbjct: 246 SSIPEKYFDKLPKLHTLRMSHNKLQDIPYNIFNLPNIVELSVGHNKLKQAFYIPRNLEHL 305
Query: 344 YVIELNLSQNEISLIG---EDLHQAPRLKILRLDENCL 240
Y+ + + ++++ + LH L +R+D+N L
Sbjct: 306 YLQNNEIEKMNLTVMCPSIDPLHY-HHLTYIRVDQNKL 342
Score = 38.3 bits (85), Expect = 0.029
Identities = 59/227 (25%), Positives = 102/227 (44%), Gaps = 13/227 (5%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKL-SVLPDDLSKLKHLKQLNLDSNKLQALPES---L 561
KLK IP ++ ++ L L N++ +V + HLK++NL NK+++
Sbjct: 82 KLKTIP----NIPMHIQQLYLQFNEIEAVTANSFINATHLKEINLSHNKIKSQKIDYGVF 137
Query: 560 INLKKLEVLNISNNFVQTLPVCL-KNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSH 384
L L L++ +N ++ P L K+L L Y +KLQ + GL +L +LDL +
Sbjct: 138 AKLPNLLQLHLEHNNLEEFPFPLPKSLERLLLGYNEISKLQT--NAMDGLVNLTMLDLCY 195
Query: 383 NKI------TEIPYGMSELYVIELNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIK 222
N + +I M +L ++LNL N + + L + L L L+ N +S K
Sbjct: 196 NYLHDSLLKDKIFAKMEKL--MQLNLCSNRLESMPPGLPSS--LMYLSLENNSISSIPEK 251
Query: 221 PSLLRDSKIHTVSVDGNLFE--PKQLAXLEGYNEYSERXTAMKKKMF 87
+ K+HT+ + N + P + L E S +K+ +
Sbjct: 252 -YFDKLPKLHTLRMSHNKLQDIPYNIFNLPNIVELSVGHNKLKQAFY 297
Score = 33.1 bits (72), Expect = 1.1
Identities = 20/74 (27%), Positives = 38/74 (51%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKK 546
+ IP F L L +S NKL +P ++ L ++ +L++ NKL+ ++ +
Sbjct: 245 ISSIPEKYFDKLPKLHTLRMSHNKLQDIPYNIFNLPNIVELSVGHNKLK---QAFYIPRN 301
Query: 545 LEVLNISNNFVQTL 504
LE L + NN ++ +
Sbjct: 302 LEHLYLQNNEIEKM 315
>AY358872-1|AAQ89231.1| 421|Homo sapiens OMD protein.
Length = 421
Score = 62.5 bits (145), Expect = 2e-09
Identities = 50/158 (31%), Positives = 84/158 (53%), Gaps = 10/158 (6%)
Frame = -2
Query: 683 LRNLDLSKNKL--SVLPDDL-SKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFV 513
L LDL N L S+L D + +K++ L QLNL SN+L+++P L + L L++ NN +
Sbjct: 188 LTMLDLCYNYLHDSLLKDKIFAKMEKLMQLNLCSNRLESMPPGLPS--SLMYLSLENNSI 245
Query: 512 QTLPV-CLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITE---IPYGMSEL 345
++P L L + S+NKLQ P I L ++ L + HNK+ + IP + L
Sbjct: 246 SSIPEKYFDKLPKLHTLRMSHNKLQDIPYNIFNLPNIVELSVGHNKLKQAFYIPRNLEHL 305
Query: 344 YVIELNLSQNEISLIG---EDLHQAPRLKILRLDENCL 240
Y+ + + ++++ + LH L +R+D+N L
Sbjct: 306 YLQNNEIEKMNLTVMCPSIDPLHY-HHLTYIRVDQNKL 342
Score = 38.3 bits (85), Expect = 0.029
Identities = 59/227 (25%), Positives = 102/227 (44%), Gaps = 13/227 (5%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKL-SVLPDDLSKLKHLKQLNLDSNKLQALPES---L 561
KLK IP ++ ++ L L N++ +V + HLK++NL NK+++
Sbjct: 82 KLKTIP----NIPMHIQQLYLQFNEIEAVTANSFINATHLKEINLSHNKIKSQKIDYGVF 137
Query: 560 INLKKLEVLNISNNFVQTLPVCL-KNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSH 384
L L L++ +N ++ P L K+L L Y +KLQ + GL +L +LDL +
Sbjct: 138 AKLPNLLQLHLEHNNLEEFPFPLPKSLERLLLGYNEISKLQT--NAMDGLVNLTMLDLCY 195
Query: 383 NKI------TEIPYGMSELYVIELNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIK 222
N + +I M +L ++LNL N + + L + L L L+ N +S K
Sbjct: 196 NYLHDSLLKDKIFAKMEKL--MQLNLCSNRLESMPPGLPSS--LMYLSLENNSISSIPEK 251
Query: 221 PSLLRDSKIHTVSVDGNLFE--PKQLAXLEGYNEYSERXTAMKKKMF 87
+ K+HT+ + N + P + L E S +K+ +
Sbjct: 252 -YFDKLPKLHTLRMSHNKLQDIPYNIFNLPNIVELSVGHNKLKQAFY 297
Score = 33.1 bits (72), Expect = 1.1
Identities = 20/74 (27%), Positives = 38/74 (51%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKK 546
+ IP F L L +S NKL +P ++ L ++ +L++ NKL+ ++ +
Sbjct: 245 ISSIPEKYFDKLPKLHTLRMSHNKLQDIPYNIFNLPNIVELSVGHNKLK---QAFYIPRN 301
Query: 545 LEVLNISNNFVQTL 504
LE L + NN ++ +
Sbjct: 302 LEHLYLQNNEIEKM 315
>AL137848-4|CAI16696.1| 421|Homo sapiens osteomodulin protein.
Length = 421
Score = 62.5 bits (145), Expect = 2e-09
Identities = 50/158 (31%), Positives = 84/158 (53%), Gaps = 10/158 (6%)
Frame = -2
Query: 683 LRNLDLSKNKL--SVLPDDL-SKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFV 513
L LDL N L S+L D + +K++ L QLNL SN+L+++P L + L L++ NN +
Sbjct: 188 LTMLDLCYNYLHDSLLKDKIFAKMEKLMQLNLCSNRLESMPPGLPS--SLMYLSLENNSI 245
Query: 512 QTLPV-CLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITE---IPYGMSEL 345
++P L L + S+NKLQ P I L ++ L + HNK+ + IP + L
Sbjct: 246 SSIPEKYFDKLPKLHTLRMSHNKLQDIPYNIFNLPNIVELSVGHNKLKQAFYIPRNLEHL 305
Query: 344 YVIELNLSQNEISLIG---EDLHQAPRLKILRLDENCL 240
Y+ + + ++++ + LH L +R+D+N L
Sbjct: 306 YLQNNEIEKMNLTVMCPSIDPLHY-HHLTYIRVDQNKL 342
Score = 38.3 bits (85), Expect = 0.029
Identities = 59/227 (25%), Positives = 102/227 (44%), Gaps = 13/227 (5%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKL-SVLPDDLSKLKHLKQLNLDSNKLQALPES---L 561
KLK IP ++ ++ L L N++ +V + HLK++NL NK+++
Sbjct: 82 KLKTIP----NIPMHIQQLYLQFNEIEAVTANSFINATHLKEINLSHNKIKSQKIDYGVF 137
Query: 560 INLKKLEVLNISNNFVQTLPVCL-KNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSH 384
L L L++ +N ++ P L K+L L Y +KLQ + GL +L +LDL +
Sbjct: 138 AKLPNLLQLHLEHNNLEEFPFPLPKSLERLLLGYNEISKLQT--NAMDGLVNLTMLDLCY 195
Query: 383 NKI------TEIPYGMSELYVIELNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIK 222
N + +I M +L ++LNL N + + L + L L L+ N +S K
Sbjct: 196 NYLHDSLLKDKIFAKMEKL--MQLNLCSNRLESMPPGLPSS--LMYLSLENNSISSIPEK 251
Query: 221 PSLLRDSKIHTVSVDGNLFE--PKQLAXLEGYNEYSERXTAMKKKMF 87
+ K+HT+ + N + P + L E S +K+ +
Sbjct: 252 -YFDKLPKLHTLRMSHNKLQDIPYNIFNLPNIVELSVGHNKLKQAFY 297
Score = 33.1 bits (72), Expect = 1.1
Identities = 20/74 (27%), Positives = 38/74 (51%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKK 546
+ IP F L L +S NKL +P ++ L ++ +L++ NKL+ ++ +
Sbjct: 245 ISSIPEKYFDKLPKLHTLRMSHNKLQDIPYNIFNLPNIVELSVGHNKLK---QAFYIPRN 301
Query: 545 LEVLNISNNFVQTL 504
LE L + NN ++ +
Sbjct: 302 LEHLYLQNNEIEKM 315
>AB009589-1|BAA23982.1| 421|Homo sapiens Osteomodulin protein.
Length = 421
Score = 62.5 bits (145), Expect = 2e-09
Identities = 50/158 (31%), Positives = 84/158 (53%), Gaps = 10/158 (6%)
Frame = -2
Query: 683 LRNLDLSKNKL--SVLPDDL-SKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFV 513
L LDL N L S+L D + +K++ L QLNL SN+L+++P L + L L++ NN +
Sbjct: 188 LTMLDLCYNYLHDSLLKDKIFAKMEKLMQLNLCSNRLESMPPGLPS--SLMYLSLENNSI 245
Query: 512 QTLPV-CLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITE---IPYGMSEL 345
++P L L + S+NKLQ P I L ++ L + HNK+ + IP + L
Sbjct: 246 SSIPEKYFDKLPKLHTLRMSHNKLQDIPYNIFNLPNIVELSVGHNKLKQAFYIPRNLEHL 305
Query: 344 YVIELNLSQNEISLIG---EDLHQAPRLKILRLDENCL 240
Y+ + + ++++ + LH L +R+D+N L
Sbjct: 306 YLQNNEIEKMNLTVMCPSIDPLHY-HHLTYIRVDQNKL 342
Score = 38.3 bits (85), Expect = 0.029
Identities = 59/227 (25%), Positives = 102/227 (44%), Gaps = 13/227 (5%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKL-SVLPDDLSKLKHLKQLNLDSNKLQALPES---L 561
KLK IP ++ ++ L L N++ +V + HLK++NL NK+++
Sbjct: 82 KLKTIP----NIPMHIQQLYLQFNEIEAVTANSFINATHLKEINLSHNKIKSQKIDYGVF 137
Query: 560 INLKKLEVLNISNNFVQTLPVCL-KNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSH 384
L L L++ +N ++ P L K+L L Y +KLQ + GL +L +LDL +
Sbjct: 138 AKLPNLLQLHLEHNNLEEFPFPLPKSLERLLLGYNEISKLQT--NAMDGLVNLTMLDLCY 195
Query: 383 NKI------TEIPYGMSELYVIELNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIK 222
N + +I M +L ++LNL N + + L + L L L+ N +S K
Sbjct: 196 NYLHDSLLKDKIFAKMEKL--MQLNLCSNRLESMPPGLPSS--LMYLSLENNSISSIPEK 251
Query: 221 PSLLRDSKIHTVSVDGNLFE--PKQLAXLEGYNEYSERXTAMKKKMF 87
+ K+HT+ + N + P + L E S +K+ +
Sbjct: 252 -YFDKLPKLHTLRMSHNKLQDIPYNIFNLPNIVELSVGHNKLKQAFY 297
Score = 33.1 bits (72), Expect = 1.1
Identities = 20/74 (27%), Positives = 38/74 (51%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKK 546
+ IP F L L +S NKL +P ++ L ++ +L++ NKL+ ++ +
Sbjct: 245 ISSIPEKYFDKLPKLHTLRMSHNKLQDIPYNIFNLPNIVELSVGHNKLK---QAFYIPRN 301
Query: 545 LEVLNISNNFVQTL 504
LE L + NN ++ +
Sbjct: 302 LEHLYLQNNEIEKM 315
>AB000114-1|BAA19055.1| 421|Homo sapiens osteomodulin protein.
Length = 421
Score = 62.5 bits (145), Expect = 2e-09
Identities = 50/158 (31%), Positives = 84/158 (53%), Gaps = 10/158 (6%)
Frame = -2
Query: 683 LRNLDLSKNKL--SVLPDDL-SKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFV 513
L LDL N L S+L D + +K++ L QLNL SN+L+++P L + L L++ NN +
Sbjct: 188 LTMLDLCYNYLHDSLLKDKIFAKMEKLMQLNLCSNRLESMPPGLPS--SLMYLSLENNSI 245
Query: 512 QTLPV-CLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITE---IPYGMSEL 345
++P L L + S+NKLQ P I L ++ L + HNK+ + IP + L
Sbjct: 246 SSIPEKYFDKLPKLHTLRMSHNKLQDIPYNIFNLPNIVELSVGHNKLKQAFYIPRNLEHL 305
Query: 344 YVIELNLSQNEISLIG---EDLHQAPRLKILRLDENCL 240
Y+ + + ++++ + LH L +R+D+N L
Sbjct: 306 YLQNNEIEKMNLTVMCPSIDPLHY-HHLTYIRVDQNKL 342
Score = 38.3 bits (85), Expect = 0.029
Identities = 59/227 (25%), Positives = 102/227 (44%), Gaps = 13/227 (5%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKL-SVLPDDLSKLKHLKQLNLDSNKLQALPES---L 561
KLK IP ++ ++ L L N++ +V + HLK++NL NK+++
Sbjct: 82 KLKTIP----NIPMHIQQLYLQFNEIEAVTANSFINATHLKEINLSHNKIKSQKIDYGVF 137
Query: 560 INLKKLEVLNISNNFVQTLPVCL-KNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSH 384
L L L++ +N ++ P L K+L L Y +KLQ + GL +L +LDL +
Sbjct: 138 AKLPNLLQLHLEHNNLEEFPFPLPKSLERLLLGYNEISKLQT--NAMDGLVNLTMLDLCY 195
Query: 383 NKI------TEIPYGMSELYVIELNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIK 222
N + +I M +L ++LNL N + + L + L L L+ N +S K
Sbjct: 196 NYLHDSLLKDKIFAKMEKL--MQLNLCSNRLESMPPGLPSS--LMYLSLENNSISSIPEK 251
Query: 221 PSLLRDSKIHTVSVDGNLFE--PKQLAXLEGYNEYSERXTAMKKKMF 87
+ K+HT+ + N + P + L E S +K+ +
Sbjct: 252 -YFDKLPKLHTLRMSHNKLQDIPYNIFNLPNIVELSVGHNKLKQAFY 297
Score = 33.1 bits (72), Expect = 1.1
Identities = 20/74 (27%), Positives = 38/74 (51%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKK 546
+ IP F L L +S NKL +P ++ L ++ +L++ NKL+ ++ +
Sbjct: 245 ISSIPEKYFDKLPKLHTLRMSHNKLQDIPYNIFNLPNIVELSVGHNKLK---QAFYIPRN 301
Query: 545 LEVLNISNNFVQTL 504
LE L + NN ++ +
Sbjct: 302 LEHLYLQNNEIEKM 315
>J04599-1|AAA36009.1| 368|Homo sapiens protein ( Human hPGI mRNA
encoding bone small proteoglycan I (biglycan), complete
cds. ).
Length = 368
Score = 62.1 bits (144), Expect = 2e-09
Identities = 55/195 (28%), Positives = 102/195 (52%), Gaps = 6/195 (3%)
Frame = -2
Query: 737 ADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVL-PDDLSKLKHLKQLNLDSNKLQALPESL 561
+D LK +P ++ +L DL N +S L DD L+HL L L +NK+ + E
Sbjct: 77 SDLGLKSVPKEISPDTTLL---DLQNNDISELRKDDFKGLQHLYALVLVNNKISKIHEKA 133
Query: 560 IN-LKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQIL-GLQSLDVLDLS 387
+ L+KL+ L IS N + +P L ++L ++ +N+++ PK + GL++++ +++
Sbjct: 134 FSPLRKLQKLYISKNHLVEIPPNLP--SSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMG 191
Query: 386 HNKITEI---PYGMSELYVIELNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPS 216
N + P L + L +S+ +++ I +DL + L L LD N + E++
Sbjct: 192 GNPLENSGFEPGAFDGLKLNYLRISEAKLTGIPKDLPET--LNELHLDHNKIQAIELE-D 248
Query: 215 LLRDSKIHTVSVDGN 171
LLR SK++ + + N
Sbjct: 249 LLRYSKLYRLGLGHN 263
>BT007323-1|AAP35987.1| 368|Homo sapiens biglycan protein.
Length = 368
Score = 62.1 bits (144), Expect = 2e-09
Identities = 55/195 (28%), Positives = 102/195 (52%), Gaps = 6/195 (3%)
Frame = -2
Query: 737 ADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVL-PDDLSKLKHLKQLNLDSNKLQALPESL 561
+D LK +P ++ +L DL N +S L DD L+HL L L +NK+ + E
Sbjct: 77 SDLGLKSVPKEISPDTTLL---DLQNNDISELRKDDFKGLQHLYALVLVNNKISKIHEKA 133
Query: 560 IN-LKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQIL-GLQSLDVLDLS 387
+ L+KL+ L IS N + +P L ++L ++ +N+++ PK + GL++++ +++
Sbjct: 134 FSPLRKLQKLYISKNHLVEIPPNLP--SSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMG 191
Query: 386 HNKITEI---PYGMSELYVIELNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPS 216
N + P L + L +S+ +++ I +DL + L L LD N + E++
Sbjct: 192 GNPLENSGFEPGAFDGLKLNYLRISEAKLTGIPKDLPET--LNELHLDHNKIQAIELE-D 248
Query: 215 LLRDSKIHTVSVDGN 171
LLR SK++ + + N
Sbjct: 249 LLRYSKLYRLGLGHN 263
>BC004244-1|AAH04244.1| 368|Homo sapiens biglycan protein.
Length = 368
Score = 62.1 bits (144), Expect = 2e-09
Identities = 55/195 (28%), Positives = 102/195 (52%), Gaps = 6/195 (3%)
Frame = -2
Query: 737 ADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVL-PDDLSKLKHLKQLNLDSNKLQALPESL 561
+D LK +P ++ +L DL N +S L DD L+HL L L +NK+ + E
Sbjct: 77 SDLGLKSVPKEISPDTTLL---DLQNNDISELRKDDFKGLQHLYALVLVNNKISKIHEKA 133
Query: 560 IN-LKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQIL-GLQSLDVLDLS 387
+ L+KL+ L IS N + +P L ++L ++ +N+++ PK + GL++++ +++
Sbjct: 134 FSPLRKLQKLYISKNHLVEIPPNLP--SSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMG 191
Query: 386 HNKITEI---PYGMSELYVIELNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPS 216
N + P L + L +S+ +++ I +DL + L L LD N + E++
Sbjct: 192 GNPLENSGFEPGAFDGLKLNYLRISEAKLTGIPKDLPET--LNELHLDHNKIQAIELE-D 248
Query: 215 LLRDSKIHTVSVDGN 171
LLR SK++ + + N
Sbjct: 249 LLRYSKLYRLGLGHN 263
>BC002416-1|AAH02416.1| 368|Homo sapiens biglycan protein.
Length = 368
Score = 62.1 bits (144), Expect = 2e-09
Identities = 55/195 (28%), Positives = 102/195 (52%), Gaps = 6/195 (3%)
Frame = -2
Query: 737 ADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVL-PDDLSKLKHLKQLNLDSNKLQALPESL 561
+D LK +P ++ +L DL N +S L DD L+HL L L +NK+ + E
Sbjct: 77 SDLGLKSVPKEISPDTTLL---DLQNNDISELRKDDFKGLQHLYALVLVNNKISKIHEKA 133
Query: 560 IN-LKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQIL-GLQSLDVLDLS 387
+ L+KL+ L IS N + +P L ++L ++ +N+++ PK + GL++++ +++
Sbjct: 134 FSPLRKLQKLYISKNHLVEIPPNLP--SSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMG 191
Query: 386 HNKITEI---PYGMSELYVIELNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPS 216
N + P L + L +S+ +++ I +DL + L L LD N + E++
Sbjct: 192 GNPLENSGFEPGAFDGLKLNYLRISEAKLTGIPKDLPET--LNELHLDHNKIQAIELE-D 248
Query: 215 LLRDSKIHTVSVDGN 171
LLR SK++ + + N
Sbjct: 249 LLRYSKLYRLGLGHN 263
>AK223302-1|BAD97022.1| 368|Homo sapiens biglycan preproprotein
variant protein.
Length = 368
Score = 62.1 bits (144), Expect = 2e-09
Identities = 55/195 (28%), Positives = 102/195 (52%), Gaps = 6/195 (3%)
Frame = -2
Query: 737 ADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVL-PDDLSKLKHLKQLNLDSNKLQALPESL 561
+D LK +P ++ +L DL N +S L DD L+HL L L +NK+ + E
Sbjct: 77 SDLGLKSVPKEISPDTTLL---DLQNNDISELRKDDFKGLQHLYALVLVNNKISKIHEKA 133
Query: 560 IN-LKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQIL-GLQSLDVLDLS 387
+ L+KL+ L IS N + +P L ++L ++ +N+++ PK + GL++++ +++
Sbjct: 134 FSPLRKLQKLYISKNHLVEIPPNLP--SSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMG 191
Query: 386 HNKITEI---PYGMSELYVIELNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPS 216
N + P L + L +S+ +++ I +DL + L L LD N + E++
Sbjct: 192 GNPLENSGFEPGAFDGLKLNYLRISEAKLTGIPKDLPET--LNELHLDHNKIQAIELE-D 248
Query: 215 LLRDSKIHTVSVDGN 171
LLR SK++ + + N
Sbjct: 249 LLRYSKLYRLGLGHN 263
>AK124678-1|BAC85924.1| 423|Homo sapiens protein ( Homo sapiens
cDNA FLJ42687 fis, clone BRAMY3001794, moderately
similar to Rattus norvegicus SCN circadian oscillatory
protein (Scop). ).
Length = 423
Score = 62.1 bits (144), Expect = 2e-09
Identities = 45/135 (33%), Positives = 67/135 (49%), Gaps = 4/135 (2%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSV-LP---DDLSKLKHLKQLNLDSNKLQALPESLI 558
L+E+P +F D+ L+L N + + P D L K LK LNL NKL P L
Sbjct: 261 LEEVPEHLFYSQDITY-LNLRHNFMQLERPGGLDTLYKFSQLKGLNLSHNKLGLFPILLC 319
Query: 557 NLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNK 378
+ L LN+S N LP + NL NL+ + N L P+++ LQ L L +S N
Sbjct: 320 EISTLTELNLSCNGFHDLPSQIGNLLNLQTLCLDGNFLTTLPEELGNLQQLSSLGISFNN 379
Query: 377 ITEIPYGMSELYVIE 333
++IP +L +++
Sbjct: 380 FSQIPEVYEKLTMLD 394
Score = 60.9 bits (141), Expect = 5e-09
Identities = 37/110 (33%), Positives = 55/110 (50%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTL 504
L+ L+LS NKL + P L ++ L +LNL N LP + NL L+ L + NF+ TL
Sbjct: 301 LKGLNLSHNKLGLFPILLCEISTLTELNLSCNGFHDLPSQIGNLLNLQTLCLDGNFLTTL 360
Query: 503 PVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGM 354
P L NL L + S N P+ L LD + ++ N + + G+
Sbjct: 361 PEELGNLQQLSSLGISFNNFSQIPEVYEKLTMLDRVVMAGNCLEVLNLGV 410
Score = 55.2 bits (127), Expect = 2e-07
Identities = 44/155 (28%), Positives = 73/155 (47%), Gaps = 5/155 (3%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQ-ALP---ESLINLKKLEVLNISNNF 516
+ +DLS L +P+ L + + LNL N +Q P ++L +L+ LN+S+N
Sbjct: 251 ISTVDLSCYSLEEVPEHLFYSQDITYLNLRHNFMQLERPGGLDTLYKFSQLKGLNLSHNK 310
Query: 515 VQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVI 336
+ P+ L ++ L ++ S N P QI L +L L L N +T +P + L +
Sbjct: 311 LGLFPILLCEISTLTELNLSCNGFHDLPSQIGNLLNLQTLCLDGNFLTTLPEELGNLQQL 370
Query: 335 -ELNLSQNEISLIGEDLHQAPRLKILRLDENCLSL 234
L +S N S I E + L + + NCL +
Sbjct: 371 SSLGISFNNFSQIPEVYEKLTMLDRVVMAGNCLEV 405
Score = 52.8 bits (121), Expect = 1e-06
Identities = 37/95 (38%), Positives = 51/95 (53%), Gaps = 3/95 (3%)
Frame = -2
Query: 695 LCDV--LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNIS- 525
LC++ L L+LS N LP + L +L+ L LD N L LPE L NL++L L IS
Sbjct: 318 LCEISTLTELNLSCNGFHDLPSQIGNLLNLQTLCLDGNFLTTLPEELGNLQQLSSLGISF 377
Query: 524 NNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQIL 420
NNF Q +P + L L +V + N L+ +L
Sbjct: 378 NNFSQ-IPEVYEKLTMLDRVVMAGNCLEVLNLGVL 411
Score = 48.8 bits (111), Expect = 2e-05
Identities = 46/170 (27%), Positives = 80/170 (47%), Gaps = 6/170 (3%)
Frame = -2
Query: 620 KHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQ-TLPVCLKNL---NNLKQVYASN 453
+ + ++L L+ +PE L + + LN+ +NF+Q P L L + LK + S+
Sbjct: 249 QRISTVDLSCYSLEEVPEHLFYSQDITYLNLRHNFMQLERPGGLDTLYKFSQLKGLNLSH 308
Query: 452 NKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVIE-LNLSQNEISLIGEDLHQAP 276
NKL FP + + +L L+LS N ++P + L ++ L L N ++ + E+L
Sbjct: 309 NKLGLFPILLCEISTLTELNLSCNGFHDLPSQIGNLLNLQTLCLDGNFLTTLPEELGNLQ 368
Query: 275 RLKILRLDENCLS-LDEIKPSLLRDSKIHTVSVDGNLFEPKQLAXLEGYN 129
+L L + N S + E+ L + + V + GN E L L N
Sbjct: 369 QLSSLGISFNNFSQIPEVYEKL---TMLDRVVMAGNCLEVLNLGVLNRMN 415
Score = 40.7 bits (91), Expect = 0.005
Identities = 24/86 (27%), Positives = 46/86 (53%), Gaps = 1/86 (1%)
Frame = -2
Query: 719 EIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLE 540
++P + +L + L+ L L N L+ LP++L L+ L L + N +PE L L+
Sbjct: 336 DLPSQIGNLLN-LQTLCLDGNFLTTLPEELGNLQQLSSLGISFNNFSQIPEVYEKLTMLD 394
Query: 539 VLNISNNFVQTLPV-CLKNLNNLKQV 465
+ ++ N ++ L + L +N++K V
Sbjct: 395 RVVMAGNCLEVLNLGVLNRMNHIKHV 420
>AF061444-1|AAC77911.1| 907|Homo sapiens G protein-coupled receptor
LGR5 protein.
Length = 907
Score = 62.1 bits (144), Expect = 2e-09
Identities = 43/150 (28%), Positives = 76/150 (50%), Gaps = 5/150 (3%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDD-LSKLKHLKQLNLDSNKLQALP-ESLIN 555
+L+ +P + L++L L N +S +P S L L+ L LD N L +P ++ +
Sbjct: 125 QLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRS 184
Query: 554 LKKLEVLNISNNFVQTLP-VCLKNLNNLKQVYASNNKLQAFPKQIL-GLQSLDVLDLSHN 381
L L+ + ++ N + +P NL++ ++ NN++ + K+ GL SL+ LDL++N
Sbjct: 185 LSALQAMTLALNKIHHIPDYAFGNLSSWVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYN 244
Query: 380 KITEIPYGMSELYVI-ELNLSQNEISLIGE 294
+ E P + L + EL N I I E
Sbjct: 245 NLDEFPTAIRTLSNLKELGFHSNNIRSIPE 274
Score = 55.6 bits (128), Expect = 2e-07
Identities = 35/123 (28%), Positives = 63/123 (51%), Gaps = 3/123 (2%)
Frame = -2
Query: 734 DCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPD-DLSKLKHLKQLNLDSNKLQALPESLI 558
D L EIP+ F L+ + L+ NK+ +PD L L+L +N++ +L +
Sbjct: 171 DNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGNLSSWVVLHLHNNRIHSLGKKCF 230
Query: 557 N-LKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFP-KQILGLQSLDVLDLSH 384
+ L LE L+++ N + P ++ L+NLK++ +N +++ P K +G SL +
Sbjct: 231 DGLHSLETLDLNYNNLDEFPTAIRTLSNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYD 290
Query: 383 NKI 375
N I
Sbjct: 291 NPI 293
Score = 41.9 bits (94), Expect = 0.002
Identities = 38/120 (31%), Positives = 58/120 (48%), Gaps = 4/120 (3%)
Frame = -2
Query: 584 LQALPESLINLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPK-QILGLQS 408
L LP +L L++ NN Q LP L +L+ L+++ + N L PK GL S
Sbjct: 57 LSELPSNLSVFTSYLDLSM-NNISQLLPNPLPSLHFLEELRLAGNALTYIPKGAFTGLYS 115
Query: 407 LDVLDLSHNKITEIP-YGMSELYVIE-LNLSQNEISLIGEDLHQA-PRLKILRLDENCLS 237
L VL L +N++ +P + L ++ L L N IS + L+ L LD+N L+
Sbjct: 116 LKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALT 175
Score = 41.1 bits (92), Expect = 0.004
Identities = 28/110 (25%), Positives = 58/110 (52%), Gaps = 3/110 (2%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPE-SLINLKKLEVLNISNNFVQT 507
L LDL+ N L P + L +LK+L SN ++++PE + + L ++ +N +Q
Sbjct: 236 LETLDLNYNNLDEFPTAIRTLSNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPIQF 295
Query: 506 L-PVCLKNLNNLKQVYASN-NKLQAFPKQILGLQSLDVLDLSHNKITEIP 363
+ ++L L+ + + +++ FP + G +L+ L L+ +I+ +P
Sbjct: 296 VGRSAFQHLPELRTLTLNGASQITEFP-DLTGTANLESLTLTGAQISSLP 344
Score = 40.3 bits (90), Expect = 0.007
Identities = 27/89 (30%), Positives = 47/89 (52%), Gaps = 1/89 (1%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVL-PDDLSKLKHLKQLNLDSNKLQALPESLINL 552
++ EI +D F LR+L+L+ NK++++ P+ S L L +L+L SN L + P + L
Sbjct: 385 EIYEIKVDTFQQLLSLRSLNLAWNKIAIIHPNAFSTLPSLIKLDLSSNLLSSFP--ITGL 442
Query: 551 KKLEVLNISNNFVQTLPVCLKNLNNLKQV 465
L L ++ N + +N LK +
Sbjct: 443 HGLTHLKLTGNHALQSLISSENFPELKVI 471
>AB023148-1|BAA76775.2| 1258|Homo sapiens KIAA0931 protein protein.
Length = 1258
Score = 62.1 bits (144), Expect = 2e-09
Identities = 45/135 (33%), Positives = 67/135 (49%), Gaps = 4/135 (2%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSV-LP---DDLSKLKHLKQLNLDSNKLQALPESLI 558
L+E+P +F D+ L+L N + + P D L K LK LNL NKL P L
Sbjct: 263 LEEVPEHLFYSQDITY-LNLRHNFMQLERPGGLDTLYKFSQLKGLNLSHNKLGLFPILLC 321
Query: 557 NLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNK 378
+ L LN+S N LP + NL NL+ + N L P+++ LQ L L +S N
Sbjct: 322 EISTLTELNLSCNGFHDLPSQIGNLLNLQTLCLDGNFLTTLPEELGNLQQLSSLGISFNN 381
Query: 377 ITEIPYGMSELYVIE 333
++IP +L +++
Sbjct: 382 FSQIPEVYEKLTMLD 396
Score = 62.1 bits (144), Expect = 2e-09
Identities = 44/152 (28%), Positives = 75/152 (49%), Gaps = 3/152 (1%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTL 504
L+ L+LS NKL + P L ++ L +LNL N LP + NL L+ L + NF+ TL
Sbjct: 303 LKGLNLSHNKLGLFPILLCEISTLTELNLSCNGFHDLPSQIGNLLNLQTLCLDGNFLTTL 362
Query: 503 PVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSEL--YVIEL 330
P L NL L + S N P+ L LD + ++ N + + G+ ++ +
Sbjct: 363 PEELGNLQQLSSLGISFNNFSQIPEVYEKLTMLDRVVMAGNCLEVLNLGVLNRMNHIKHV 422
Query: 329 NLSQNEI-SLIGEDLHQAPRLKILRLDENCLS 237
+L N + +++ E+L + + L +N L+
Sbjct: 423 DLRMNHLKTMVIENLEGNKHITHVDLRDNRLT 454
Score = 60.5 bits (140), Expect = 6e-09
Identities = 50/181 (27%), Positives = 92/181 (50%), Gaps = 12/181 (6%)
Frame = -2
Query: 710 IDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLN 531
++V+ + +L LDLS+N L +PD + K ++ L++ N L +P +++ L L
Sbjct: 497 VNVYPVPSLLTFLDLSRNLLECVPDWACEAKKIEVLDVSYNLLTEVPVRILSSLSLRKLM 556
Query: 530 ISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILG--------LQSLDVLDLSHNKI 375
+ +N VQ LP ++++ L+ + +N L P + L+ L+ L+LS NK+
Sbjct: 557 LGHNHVQNLPTLVEHI-PLEVLDLQHNALTRLPDTLFSKALNKLNKLEQLEELNLSGNKL 615
Query: 374 TEIPYGMSELYVIE-LNLSQNEISLIGEDLHQAPRLKILRLDENCLS---LDEIKPSLLR 207
IP ++ + L N IS+ E L Q P+++ + L N L+ + E P+ L+
Sbjct: 616 KTIPTTIANCKRLHTLVAHSNNISIFPEIL-QLPQIQFVDLSCNDLTEILIPEALPATLQ 674
Query: 206 D 204
D
Sbjct: 675 D 675
Score = 56.0 bits (129), Expect = 1e-07
Identities = 52/188 (27%), Positives = 86/188 (45%), Gaps = 5/188 (2%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQ-ALP---ESLINLKKLEVLNISNNF 516
+ +DLS L +P+ L + + LNL N +Q P ++L +L+ LN+S+N
Sbjct: 253 ISTVDLSCYSLEEVPEHLFYSQDITYLNLRHNFMQLERPGGLDTLYKFSQLKGLNLSHNK 312
Query: 515 VQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVI 336
+ P+ L ++ L ++ S N P QI L +L L L N +T +P + L +
Sbjct: 313 LGLFPILLCEISTLTELNLSCNGFHDLPSQIGNLLNLQTLCLDGNFLTTLPEELGNLQQL 372
Query: 335 -ELNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIHTVSVDGNLFEP 159
L +S N S I E + L + + NCL + + L R + I V + N +
Sbjct: 373 SSLGISFNNFSQIPEVYEKLTMLDRVVMAGNCLEVLNL-GVLNRMNHIKHVDLRMNHLKT 431
Query: 158 KQLAXLEG 135
+ LEG
Sbjct: 432 MVIENLEG 439
Score = 48.8 bits (111), Expect = 2e-05
Identities = 46/170 (27%), Positives = 80/170 (47%), Gaps = 6/170 (3%)
Frame = -2
Query: 620 KHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQ-TLPVCLKNL---NNLKQVYASN 453
+ + ++L L+ +PE L + + LN+ +NF+Q P L L + LK + S+
Sbjct: 251 QRISTVDLSCYSLEEVPEHLFYSQDITYLNLRHNFMQLERPGGLDTLYKFSQLKGLNLSH 310
Query: 452 NKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVIE-LNLSQNEISLIGEDLHQAP 276
NKL FP + + +L L+LS N ++P + L ++ L L N ++ + E+L
Sbjct: 311 NKLGLFPILLCEISTLTELNLSCNGFHDLPSQIGNLLNLQTLCLDGNFLTTLPEELGNLQ 370
Query: 275 RLKILRLDENCLS-LDEIKPSLLRDSKIHTVSVDGNLFEPKQLAXLEGYN 129
+L L + N S + E+ L + + V + GN E L L N
Sbjct: 371 QLSSLGISFNNFSQIPEVYEKL---TMLDRVVMAGNCLEVLNLGVLNRMN 417
>AL356953-5|CAI15931.1| 232|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 6 protein.
Length = 232
Score = 61.3 bits (142), Expect = 4e-09
Identities = 56/163 (34%), Positives = 81/163 (49%), Gaps = 6/163 (3%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDD-LSKLKHLKQLNLDSNKLQALPE-SLINL 552
L IP FS L+ L L N+L +P + L +L L+ L LD+N + +PE S L
Sbjct: 28 LSHIPGQAFSGLYSLKILMLQNNQLGGIPAEALWELPSLQSLRLDANLISLVPERSFEGL 87
Query: 551 KKLEVLNISNNFVQTLPV-CLKNLNNLKQVYASNNKLQAFPKQIL-GLQSLDVLDLSHNK 378
L L + +N + +PV L NL L+ + + N++ P L SL VLDL++NK
Sbjct: 88 SSLRHLWLDDNALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTSLVVLDLNYNK 147
Query: 377 ITEIPYGMSELYVIELNLSQNEISLIGE--DLHQAPRLKILRL 255
+ E P + L ++ LS N I E DL L+IL L
Sbjct: 148 LQEFPVAIRTLGRLQ-ELSLNGAMDIQEFPDLKGTTSLEILTL 189
Score = 56.0 bits (129), Expect = 1e-07
Identities = 40/127 (31%), Positives = 68/127 (53%), Gaps = 3/127 (2%)
Frame = -2
Query: 734 DCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPD-DLSKLKHLKQLNLDSNKLQALPESLI 558
D L EIP+ + L+ + L+ N++S +PD L L L+L+ NKLQ P ++
Sbjct: 97 DNALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTSLVVLDLNYNKLQEFPVAIR 156
Query: 557 NLKKLEVLNISNNF-VQTLPVCLKNLNNLKQVYASNNKLQAFPKQILG-LQSLDVLDLSH 384
L +L+ L+++ +Q P LK +L+ + + ++ P + L L VL+LSH
Sbjct: 157 TLGRLQELSLNGAMDIQEFPD-LKGTTSLEILTLTRAGIRLLPSGMCQQLPRLRVLELSH 215
Query: 383 NKITEIP 363
N+I E+P
Sbjct: 216 NQIEELP 222
>AB033020-1|BAA86508.1| 575|Homo sapiens KIAA1194 protein protein.
Length = 575
Score = 61.3 bits (142), Expect = 4e-09
Identities = 35/95 (36%), Positives = 56/95 (58%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
K++ + ++SL L L LS N LS +P D++KL +L L+L SNK+++LP L N+
Sbjct: 57 KVRSLSASLWSLTH-LTALHLSDNSLSRIPSDIAKLHNLVYLDLSSNKIRSLPAELGNMV 115
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKL 444
L L+++NN ++ LP L L L+ + N L
Sbjct: 116 SLRELHLNNNLLRVLPFELGKLFQLQTLGLKGNPL 150
Score = 59.7 bits (138), Expect = 1e-08
Identities = 33/102 (32%), Positives = 57/102 (55%)
Frame = -2
Query: 674 LDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTLPVC 495
L++S K+ L L L HL L+L N L +P + L L L++S+N +++LP
Sbjct: 52 LEIS-GKVRSLSASLWSLTHLTALHLSDNSLSRIPSDIAKLHNLVYLDLSSNKIRSLPAE 110
Query: 494 LKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITE 369
L N+ +L++++ +NN L+ P ++ L L L L N +T+
Sbjct: 111 LGNMVSLRELHLNNNLLRVLPFELGKLFQLQTLGLKGNPLTQ 152
Score = 57.6 bits (133), Expect = 4e-08
Identities = 34/118 (28%), Positives = 69/118 (58%), Gaps = 1/118 (0%)
Frame = -2
Query: 626 KLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNK 447
K H +L + S K+++L SL +L L L++S+N + +P + L+NL + S+NK
Sbjct: 45 KKSHWAELEI-SGKVRSLSASLWSLTHLTALHLSDNSLSRIPSDIAKLHNLVYLDLSSNK 103
Query: 446 LQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVIE-LNLSQNEISLIGEDLHQAP 276
+++ P ++ + SL L L++N + +P+ + +L+ ++ L L N ++ +L+Q P
Sbjct: 104 IRSLPAELGNMVSLRELHLNNNLLRVLPFELGKLFQLQTLGLKGNPLTQDILNLYQEP 161
>BC113717-1|AAI13718.1| 581|Homo sapiens leucine rich repeat
transmembrane neuronal 3 protein.
Length = 581
Score = 60.5 bits (140), Expect = 6e-09
Identities = 59/184 (32%), Positives = 97/184 (52%), Gaps = 10/184 (5%)
Frame = -2
Query: 683 LRNLDLSKNKL-SVLPDDLSKLKHLKQLNLDSNKLQALPESLI-NLKKLEVLNISNNFVQ 510
LRNLDLS N+L S+ + L+ L L+L SN L+ +P + + + LE+L++ N ++
Sbjct: 135 LRNLDLSYNQLHSLGSEQFRGLRKLLSLHLRSNSLRTIPVRIFQDCRNLELLDLGYNRIR 194
Query: 509 TLP-VCLKNLNNLKQVYASNNKLQAFPKQIL-GLQSLDVLDLSHNKITEIPYGMSELY-- 342
+L + LK+++ +N+ + L SL L L NKI+ I MS +
Sbjct: 195 SLARNVFAGMIRLKELHLEHNQFSKLNLALFPRLVSLQNLYLQWNKISVIGQTMSWTWSS 254
Query: 341 VIELNLSQNEI-SLIGEDLHQ-APRLKILRLDENCLSL--DEIKPSLLRDSKIHTVSVDG 174
+ L+LS NEI + G + Q P L+ L LD N L+ EI S + ++ +S+ G
Sbjct: 255 LQRLDLSGNEIEAFSGPSVFQCVPNLQRLNLDSNKLTFIGQEILDSWI---SLNDISLAG 311
Query: 173 NLFE 162
N++E
Sbjct: 312 NIWE 315
Score = 47.2 bits (107), Expect = 6e-05
Identities = 42/148 (28%), Positives = 78/148 (52%), Gaps = 5/148 (3%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKL-SVLPDDLSKLKHLKQLNLDSNKLQALPESLI-NL 552
L+ IP+ +F C L LDL N++ S+ + + + LK+L+L+ N+ L +L L
Sbjct: 169 LRTIPVRIFQDCRNLELLDLGYNRIRSLARNVFAGMIRLKELHLEHNQFSKLNLALFPRL 228
Query: 551 KKLEVLNISNNFVQTLPVCLK-NLNNLKQVYASNNKLQAF--PKQILGLQSLDVLDLSHN 381
L+ L + N + + + ++L+++ S N+++AF P + +L L+L N
Sbjct: 229 VSLQNLYLQWNKISVIGQTMSWTWSSLQRLDLSGNEIEAFSGPSVFQCVPNLQRLNLDSN 288
Query: 380 KITEIPYGMSELYVIELNLSQNEISLIG 297
K+T I G +++ +S N+ISL G
Sbjct: 289 KLTFI--GQE---ILDSWISLNDISLAG 311
Score = 35.9 bits (79), Expect = 0.15
Identities = 27/101 (26%), Positives = 51/101 (50%), Gaps = 5/101 (4%)
Frame = -2
Query: 683 LRNLDLSKNKLSVL--PDDLSKLKHLKQLNLDSNKLQALPESLI-NLKKLEVLNISNNFV 513
L+ LDLS N++ P + +L++LNLDSNKL + + ++ + L ++++ N
Sbjct: 255 LQRLDLSGNEIEAFSGPSVFQCVPNLQRLNLDSNKLTFIGQEILDSWISLNDISLAGNIW 314
Query: 512 QTLPVCLKNLNNLKQV--YASNNKLQAFPKQILGLQSLDVL 396
+ +N LK N + A PK++ G+ +D +
Sbjct: 315 ECSRNICSLVNWLKSFKGLRENTIICASPKELQGVNVIDAV 355
>BC113715-1|AAI13716.1| 581|Homo sapiens leucine rich repeat
transmembrane neuronal 3 protein.
Length = 581
Score = 60.5 bits (140), Expect = 6e-09
Identities = 59/184 (32%), Positives = 97/184 (52%), Gaps = 10/184 (5%)
Frame = -2
Query: 683 LRNLDLSKNKL-SVLPDDLSKLKHLKQLNLDSNKLQALPESLI-NLKKLEVLNISNNFVQ 510
LRNLDLS N+L S+ + L+ L L+L SN L+ +P + + + LE+L++ N ++
Sbjct: 135 LRNLDLSYNQLHSLGSEQFRGLRKLLSLHLRSNSLRTIPVRIFQDCRNLELLDLGYNRIR 194
Query: 509 TLP-VCLKNLNNLKQVYASNNKLQAFPKQIL-GLQSLDVLDLSHNKITEIPYGMSELY-- 342
+L + LK+++ +N+ + L SL L L NKI+ I MS +
Sbjct: 195 SLARNVFAGMIRLKELHLEHNQFSKLNLALFPRLVSLQNLYLQWNKISVIGQTMSWTWSS 254
Query: 341 VIELNLSQNEI-SLIGEDLHQ-APRLKILRLDENCLSL--DEIKPSLLRDSKIHTVSVDG 174
+ L+LS NEI + G + Q P L+ L LD N L+ EI S + ++ +S+ G
Sbjct: 255 LQRLDLSGNEIEAFSGPSVFQCVPNLQRLNLDSNKLTFIGQEILDSWI---SLNDISLAG 311
Query: 173 NLFE 162
N++E
Sbjct: 312 NIWE 315
Score = 47.2 bits (107), Expect = 6e-05
Identities = 42/148 (28%), Positives = 78/148 (52%), Gaps = 5/148 (3%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKL-SVLPDDLSKLKHLKQLNLDSNKLQALPESLI-NL 552
L+ IP+ +F C L LDL N++ S+ + + + LK+L+L+ N+ L +L L
Sbjct: 169 LRTIPVRIFQDCRNLELLDLGYNRIRSLARNVFAGMIRLKELHLEHNQFSKLNLALFPRL 228
Query: 551 KKLEVLNISNNFVQTLPVCLK-NLNNLKQVYASNNKLQAF--PKQILGLQSLDVLDLSHN 381
L+ L + N + + + ++L+++ S N+++AF P + +L L+L N
Sbjct: 229 VSLQNLYLQWNKISVIGQTMSWTWSSLQRLDLSGNEIEAFSGPSVFQCVPNLQRLNLDSN 288
Query: 380 KITEIPYGMSELYVIELNLSQNEISLIG 297
K+T I G +++ +S N+ISL G
Sbjct: 289 KLTFI--GQE---ILDSWISLNDISLAG 311
Score = 35.9 bits (79), Expect = 0.15
Identities = 27/101 (26%), Positives = 51/101 (50%), Gaps = 5/101 (4%)
Frame = -2
Query: 683 LRNLDLSKNKLSVL--PDDLSKLKHLKQLNLDSNKLQALPESLI-NLKKLEVLNISNNFV 513
L+ LDLS N++ P + +L++LNLDSNKL + + ++ + L ++++ N
Sbjct: 255 LQRLDLSGNEIEAFSGPSVFQCVPNLQRLNLDSNKLTFIGQEILDSWISLNDISLAGNIW 314
Query: 512 QTLPVCLKNLNNLKQV--YASNNKLQAFPKQILGLQSLDVL 396
+ +N LK N + A PK++ G+ +D +
Sbjct: 315 ECSRNICSLVNWLKSFKGLRENTIICASPKELQGVNVIDAV 355
>BC111492-1|AAI11493.1| 581|Homo sapiens leucine rich repeat
transmembrane neuronal 3 protein.
Length = 581
Score = 60.5 bits (140), Expect = 6e-09
Identities = 59/184 (32%), Positives = 97/184 (52%), Gaps = 10/184 (5%)
Frame = -2
Query: 683 LRNLDLSKNKL-SVLPDDLSKLKHLKQLNLDSNKLQALPESLI-NLKKLEVLNISNNFVQ 510
LRNLDLS N+L S+ + L+ L L+L SN L+ +P + + + LE+L++ N ++
Sbjct: 135 LRNLDLSYNQLHSLGSEQFRGLRKLLSLHLRSNSLRTIPVRIFQDCRNLELLDLGYNRIR 194
Query: 509 TLP-VCLKNLNNLKQVYASNNKLQAFPKQIL-GLQSLDVLDLSHNKITEIPYGMSELY-- 342
+L + LK+++ +N+ + L SL L L NKI+ I MS +
Sbjct: 195 SLARNVFAGMIRLKELHLEHNQFSKLNLALFPRLVSLQNLYLQWNKISVIGQTMSWTWSS 254
Query: 341 VIELNLSQNEI-SLIGEDLHQ-APRLKILRLDENCLSL--DEIKPSLLRDSKIHTVSVDG 174
+ L+LS NEI + G + Q P L+ L LD N L+ EI S + ++ +S+ G
Sbjct: 255 LQRLDLSGNEIEAFSGPSVFQCVPNLQRLNLDSNKLTFIGQEILDSWI---SLNDISLAG 311
Query: 173 NLFE 162
N++E
Sbjct: 312 NIWE 315
Score = 47.2 bits (107), Expect = 6e-05
Identities = 42/148 (28%), Positives = 78/148 (52%), Gaps = 5/148 (3%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKL-SVLPDDLSKLKHLKQLNLDSNKLQALPESLI-NL 552
L+ IP+ +F C L LDL N++ S+ + + + LK+L+L+ N+ L +L L
Sbjct: 169 LRTIPVRIFQDCRNLELLDLGYNRIRSLARNVFAGMIRLKELHLEHNQFSKLNLALFPRL 228
Query: 551 KKLEVLNISNNFVQTLPVCLK-NLNNLKQVYASNNKLQAF--PKQILGLQSLDVLDLSHN 381
L+ L + N + + + ++L+++ S N+++AF P + +L L+L N
Sbjct: 229 VSLQNLYLQWNKISVIGQTMSWTWSSLQRLDLSGNEIEAFSGPSVFQCVPNLQRLNLDSN 288
Query: 380 KITEIPYGMSELYVIELNLSQNEISLIG 297
K+T I G +++ +S N+ISL G
Sbjct: 289 KLTFI--GQE---ILDSWISLNDISLAG 311
Score = 35.9 bits (79), Expect = 0.15
Identities = 27/101 (26%), Positives = 51/101 (50%), Gaps = 5/101 (4%)
Frame = -2
Query: 683 LRNLDLSKNKLSVL--PDDLSKLKHLKQLNLDSNKLQALPESLI-NLKKLEVLNISNNFV 513
L+ LDLS N++ P + +L++LNLDSNKL + + ++ + L ++++ N
Sbjct: 255 LQRLDLSGNEIEAFSGPSVFQCVPNLQRLNLDSNKLTFIGQEILDSWISLNDISLAGNIW 314
Query: 512 QTLPVCLKNLNNLKQV--YASNNKLQAFPKQILGLQSLDVL 396
+ +N LK N + A PK++ G+ +D +
Sbjct: 315 ECSRNICSLVNWLKSFKGLRENTIICASPKELQGVNVIDAV 355
>BC040879-1|AAH40879.1| 493|Homo sapiens adhesion molecule with
Ig-like domain 1 protein.
Length = 493
Score = 60.5 bits (140), Expect = 6e-09
Identities = 39/114 (34%), Positives = 67/114 (58%), Gaps = 7/114 (6%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDD-LSKLKHLKQLNLDSNKLQALPESLIN-LKKLEVLNISNNFVQ 510
L +L LS N L+ + + S + +L+ L+L SN+L+ L E L + L+ LEVL + NN +
Sbjct: 88 LHSLLLSHNHLNFISSEAFSPVPNLRYLDLSSNQLRTLDEFLFSDLQVLEVLLLYNNHIM 147
Query: 509 TLPVC-LKNLNNLKQVYASNNKLQAFPKQILG----LQSLDVLDLSHNKITEIP 363
+ C ++ L+++Y S N++ FP +++ L L +LDLS NK+ +P
Sbjct: 148 AVDRCAFDDMAQLQKLYLSQNQISRFPLELVKEGAKLPKLTLLDLSSNKLKNLP 201
>AY358315-1|AAQ88681.1| 513|Homo sapiens GFNV803 protein.
Length = 513
Score = 60.5 bits (140), Expect = 6e-09
Identities = 59/184 (32%), Positives = 97/184 (52%), Gaps = 10/184 (5%)
Frame = -2
Query: 683 LRNLDLSKNKL-SVLPDDLSKLKHLKQLNLDSNKLQALPESLI-NLKKLEVLNISNNFVQ 510
LRNLDLS N+L S+ + L+ L L+L SN L+ +P + + + LE+L++ N ++
Sbjct: 135 LRNLDLSYNQLHSLGSEQFRGLRKLLSLHLRSNSLRTIPVRIFQDCRNLELLDLGYNRIR 194
Query: 509 TLP-VCLKNLNNLKQVYASNNKLQAFPKQIL-GLQSLDVLDLSHNKITEIPYGMSELY-- 342
+L + LK+++ +N+ + L SL L L NKI+ I MS +
Sbjct: 195 SLARNVFAGMIRLKELHLEHNQFSKLNLALFPRLVSLQNLYLQWNKISVIGQTMSWTWSS 254
Query: 341 VIELNLSQNEI-SLIGEDLHQ-APRLKILRLDENCLSL--DEIKPSLLRDSKIHTVSVDG 174
+ L+LS NEI + G + Q P L+ L LD N L+ EI S + ++ +S+ G
Sbjct: 255 LQRLDLSGNEIEAFSGPSVFQCVPNLQRLNLDSNKLTFIGQEILDSWI---SLNDISLAG 311
Query: 173 NLFE 162
N++E
Sbjct: 312 NIWE 315
Score = 47.2 bits (107), Expect = 6e-05
Identities = 42/148 (28%), Positives = 78/148 (52%), Gaps = 5/148 (3%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKL-SVLPDDLSKLKHLKQLNLDSNKLQALPESLI-NL 552
L+ IP+ +F C L LDL N++ S+ + + + LK+L+L+ N+ L +L L
Sbjct: 169 LRTIPVRIFQDCRNLELLDLGYNRIRSLARNVFAGMIRLKELHLEHNQFSKLNLALFPRL 228
Query: 551 KKLEVLNISNNFVQTLPVCLK-NLNNLKQVYASNNKLQAF--PKQILGLQSLDVLDLSHN 381
L+ L + N + + + ++L+++ S N+++AF P + +L L+L N
Sbjct: 229 VSLQNLYLQWNKISVIGQTMSWTWSSLQRLDLSGNEIEAFSGPSVFQCVPNLQRLNLDSN 288
Query: 380 KITEIPYGMSELYVIELNLSQNEISLIG 297
K+T I G +++ +S N+ISL G
Sbjct: 289 KLTFI--GQE---ILDSWISLNDISLAG 311
Score = 35.9 bits (79), Expect = 0.15
Identities = 27/101 (26%), Positives = 51/101 (50%), Gaps = 5/101 (4%)
Frame = -2
Query: 683 LRNLDLSKNKLSVL--PDDLSKLKHLKQLNLDSNKLQALPESLI-NLKKLEVLNISNNFV 513
L+ LDLS N++ P + +L++LNLDSNKL + + ++ + L ++++ N
Sbjct: 255 LQRLDLSGNEIEAFSGPSVFQCVPNLQRLNLDSNKLTFIGQEILDSWISLNDISLAGNIW 314
Query: 512 QTLPVCLKNLNNLKQV--YASNNKLQAFPKQILGLQSLDVL 396
+ +N LK N + A PK++ G+ +D +
Sbjct: 315 ECSRNICSLVNWLKSFKGLRENTIICASPKELQGVNVIDAV 355
>AY237007-1|AAO48948.1| 493|Homo sapiens transmembrane protein
AMIGO protein.
Length = 493
Score = 60.5 bits (140), Expect = 6e-09
Identities = 39/114 (34%), Positives = 67/114 (58%), Gaps = 7/114 (6%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDD-LSKLKHLKQLNLDSNKLQALPESLIN-LKKLEVLNISNNFVQ 510
L +L LS N L+ + + S + +L+ L+L SN+L+ L E L + L+ LEVL + NN +
Sbjct: 88 LHSLLLSHNHLNFISSEAFSPVPNLRYLDLSSNQLRTLDEFLFSDLQVLEVLLLYNNHIM 147
Query: 509 TLPVC-LKNLNNLKQVYASNNKLQAFPKQILG----LQSLDVLDLSHNKITEIP 363
+ C ++ L+++Y S N++ FP +++ L L +LDLS NK+ +P
Sbjct: 148 AVDRCAFDDMAQLQKLYLSQNQISRFPLELVKEGAKLPKLTLLDLSSNKLKNLP 201
>AY182028-1|AAO67549.1| 513|Homo sapiens leucine-rich repeat
transmembrane neuronal 3 protein protein.
Length = 513
Score = 60.5 bits (140), Expect = 6e-09
Identities = 59/184 (32%), Positives = 97/184 (52%), Gaps = 10/184 (5%)
Frame = -2
Query: 683 LRNLDLSKNKL-SVLPDDLSKLKHLKQLNLDSNKLQALPESLI-NLKKLEVLNISNNFVQ 510
LRNLDLS N+L S+ + L+ L L+L SN L+ +P + + + LE+L++ N ++
Sbjct: 135 LRNLDLSYNQLHSLGSEQFRGLRKLLSLHLRSNSLRTIPVRIFQDCRNLELLDLGYNRIR 194
Query: 509 TLP-VCLKNLNNLKQVYASNNKLQAFPKQIL-GLQSLDVLDLSHNKITEIPYGMSELY-- 342
+L + LK+++ +N+ + L SL L L NKI+ I MS +
Sbjct: 195 SLARNVFAGMIRLKELHLEHNQFSKLNLALFPRLVSLQNLYLQWNKISVIGQTMSWTWSS 254
Query: 341 VIELNLSQNEI-SLIGEDLHQ-APRLKILRLDENCLSL--DEIKPSLLRDSKIHTVSVDG 174
+ L+LS NEI + G + Q P L+ L LD N L+ EI S + ++ +S+ G
Sbjct: 255 LQRLDLSGNEIEAFSGPSVFQCVPNLQRLNLDSNKLTFIGQEILDSWI---SLNDISLAG 311
Query: 173 NLFE 162
N++E
Sbjct: 312 NIWE 315
Score = 47.2 bits (107), Expect = 6e-05
Identities = 42/148 (28%), Positives = 78/148 (52%), Gaps = 5/148 (3%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKL-SVLPDDLSKLKHLKQLNLDSNKLQALPESLI-NL 552
L+ IP+ +F C L LDL N++ S+ + + + LK+L+L+ N+ L +L L
Sbjct: 169 LRTIPVRIFQDCRNLELLDLGYNRIRSLARNVFAGMIRLKELHLEHNQFSKLNLALFPRL 228
Query: 551 KKLEVLNISNNFVQTLPVCLK-NLNNLKQVYASNNKLQAF--PKQILGLQSLDVLDLSHN 381
L+ L + N + + + ++L+++ S N+++AF P + +L L+L N
Sbjct: 229 VSLQNLYLQWNKISVIGQTMSWTWSSLQRLDLSGNEIEAFSGPSVFQCVPNLQRLNLDSN 288
Query: 380 KITEIPYGMSELYVIELNLSQNEISLIG 297
K+T I G +++ +S N+ISL G
Sbjct: 289 KLTFI--GQE---ILDSWISLNDISLAG 311
Score = 35.9 bits (79), Expect = 0.15
Identities = 27/101 (26%), Positives = 51/101 (50%), Gaps = 5/101 (4%)
Frame = -2
Query: 683 LRNLDLSKNKLSVL--PDDLSKLKHLKQLNLDSNKLQALPESLI-NLKKLEVLNISNNFV 513
L+ LDLS N++ P + +L++LNLDSNKL + + ++ + L ++++ N
Sbjct: 255 LQRLDLSGNEIEAFSGPSVFQCVPNLQRLNLDSNKLTFIGQEILDSWISLNDISLAGNIW 314
Query: 512 QTLPVCLKNLNNLKQV--YASNNKLQAFPKQILGLQSLDVL 396
+ +N LK N + A PK++ G+ +D +
Sbjct: 315 ECSRNICSLVNWLKSFKGLRENTIICASPKELQGVNVIDAV 355
>AL355145-6|CAI22942.1| 493|Homo sapiens adhesion molecule with
Ig-like domain 1 protein.
Length = 493
Score = 60.5 bits (140), Expect = 6e-09
Identities = 39/114 (34%), Positives = 67/114 (58%), Gaps = 7/114 (6%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDD-LSKLKHLKQLNLDSNKLQALPESLIN-LKKLEVLNISNNFVQ 510
L +L LS N L+ + + S + +L+ L+L SN+L+ L E L + L+ LEVL + NN +
Sbjct: 88 LHSLLLSHNHLNFISSEAFSPVPNLRYLDLSSNQLRTLDEFLFSDLQVLEVLLLYNNHIM 147
Query: 509 TLPVC-LKNLNNLKQVYASNNKLQAFPKQILG----LQSLDVLDLSHNKITEIP 363
+ C ++ L+++Y S N++ FP +++ L L +LDLS NK+ +P
Sbjct: 148 AVDRCAFDDMAQLQKLYLSQNQISRFPLELVKEGAKLPKLTLLDLSSNKLKNLP 201
>AK222484-1|BAD96204.1| 368|Homo sapiens biglycan preproprotein
variant protein.
Length = 368
Score = 60.5 bits (140), Expect = 6e-09
Identities = 54/195 (27%), Positives = 102/195 (52%), Gaps = 6/195 (3%)
Frame = -2
Query: 737 ADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVL-PDDLSKLKHLKQLNLDSNKLQALPESL 561
+D LK +P ++ +L DL N +S L DD L+HL L L +NK+ + E
Sbjct: 77 SDLGLKSVPKEISPDTTLL---DLQNNDISELRKDDFKGLQHLYALVLVNNKISKIHEKA 133
Query: 560 IN-LKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQIL-GLQSLDVLDLS 387
+ L+KL+ L IS N + +P L ++L ++ +N+++ P+ + GL++++ +++
Sbjct: 134 FSPLRKLQKLYISKNHLVEIPPNLP--SSLVELRIHDNRIRKVPEGVFSGLRNMNCIEMG 191
Query: 386 HNKITEI---PYGMSELYVIELNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPS 216
N + P L + L +S+ +++ I +DL + L L LD N + E++
Sbjct: 192 GNPLENSGFEPGAFDGLKLNYLRISEAKLTGIPKDLPET--LNELHLDHNKIQAIELE-D 248
Query: 215 LLRDSKIHTVSVDGN 171
LLR SK++ + + N
Sbjct: 249 LLRYSKLYRLGLGHN 263
>AB032989-1|BAA86477.1| 437|Homo sapiens KIAA1163 protein protein.
Length = 437
Score = 60.5 bits (140), Expect = 6e-09
Identities = 39/114 (34%), Positives = 67/114 (58%), Gaps = 7/114 (6%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDD-LSKLKHLKQLNLDSNKLQALPESLIN-LKKLEVLNISNNFVQ 510
L +L LS N L+ + + S + +L+ L+L SN+L+ L E L + L+ LEVL + NN +
Sbjct: 32 LHSLLLSHNHLNFISSEAFSPVPNLRYLDLSSNQLRTLDEFLFSDLQVLEVLLLYNNHIM 91
Query: 509 TLPVC-LKNLNNLKQVYASNNKLQAFPKQILG----LQSLDVLDLSHNKITEIP 363
+ C ++ L+++Y S N++ FP +++ L L +LDLS NK+ +P
Sbjct: 92 AVDRCAFDDMAQLQKLYLSQNQISRFPLELVKEGAKLPKLTLLDLSSNKLKNLP 145
>X57436-1|CAA40684.1| 440|Homo sapiens oligodentrocyte-myelin
glycoprotein protein.
Length = 440
Score = 60.1 bits (139), Expect = 8e-09
Identities = 40/104 (38%), Positives = 58/104 (55%), Gaps = 2/104 (1%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNN-FVQT 507
L+ LD+SKN L + + L+ L+ LNL SNKL +P ++ + KL ++++SNN Q
Sbjct: 125 LKYLDVSKNMLEKVVLIKNTLRSLEVLNLSSNKLWTVPTNMPS--KLHIVDLSNNSLTQI 182
Query: 506 LPVCLKNLNNLKQVYASNNKLQAFPKQILG-LQSLDVLDLSHNK 378
LP L NL NL +Y NNK P Q L L + L +N+
Sbjct: 183 LPGTLINLTNLTHLYLHNNKFTFIPDQSFDQLFQLQEITLYNNR 226
Score = 54.8 bits (126), Expect = 3e-07
Identities = 43/147 (29%), Positives = 81/147 (55%), Gaps = 2/147 (1%)
Frame = -2
Query: 734 DCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLIN 555
DC + + L + + +L+LS N + L + L++ +L+ L++ +N+L++LP L
Sbjct: 40 DCSGRNLSTLPSGLQENIIHLNLSYNHFTDLHNQLTQYTNLRTLDISNNRLESLPAHL-- 97
Query: 554 LKKLEVLNISNNFVQTLPVCLKNLN-NLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNK 378
+ L ++ +NN ++ L NLK + S N L+ L+SL+VL+LS NK
Sbjct: 98 PRSLWNMSAANNNIKLLDKSDTAYQWNLKYLDVSKNMLEKVVLIKNTLRSLEVLNLSSNK 157
Query: 377 ITEIPYGM-SELYVIELNLSQNEISLI 300
+ +P M S+L++++ LS N ++ I
Sbjct: 158 LWTVPTNMPSKLHIVD--LSNNSLTQI 182
>X51694-1|CAA35991.1| 433|Homo sapiens oligodendrocyte-myelin
glycoprotein protein.
Length = 433
Score = 60.1 bits (139), Expect = 8e-09
Identities = 40/104 (38%), Positives = 58/104 (55%), Gaps = 2/104 (1%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNN-FVQT 507
L+ LD+SKN L + + L+ L+ LNL SNKL +P ++ + KL ++++SNN Q
Sbjct: 118 LKYLDVSKNMLEKVVLIKNTLRSLEVLNLSSNKLWTVPTNMPS--KLHIVDLSNNSLTQI 175
Query: 506 LPVCLKNLNNLKQVYASNNKLQAFPKQILG-LQSLDVLDLSHNK 378
LP L NL NL +Y NNK P Q L L + L +N+
Sbjct: 176 LPGTLINLTNLTHLYLHNNKFTFIPDQSFDQLFQLQEITLYNNR 219
Score = 54.8 bits (126), Expect = 3e-07
Identities = 43/147 (29%), Positives = 81/147 (55%), Gaps = 2/147 (1%)
Frame = -2
Query: 734 DCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLIN 555
DC + + L + + +L+LS N + L + L++ +L+ L++ +N+L++LP L
Sbjct: 33 DCSGRNLSTLPSGLQENIIHLNLSYNHFTDLHNQLTQYTNLRTLDISNNRLESLPAHL-- 90
Query: 554 LKKLEVLNISNNFVQTLPVCLKNLN-NLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNK 378
+ L ++ +NN ++ L NLK + S N L+ L+SL+VL+LS NK
Sbjct: 91 PRSLWNMSAANNNIKLLDKSDTAYQWNLKYLDVSKNMLEKVVLIKNTLRSLEVLNLSSNK 150
Query: 377 ITEIPYGM-SELYVIELNLSQNEISLI 300
+ +P M S+L++++ LS N ++ I
Sbjct: 151 LWTVPTNMPSKLHIVD--LSNNSLTQI 175
>M63623-1|AAA59970.1| 440|Homo sapiens oligodendrocyte-myelin
glycoprotein protein.
Length = 440
Score = 60.1 bits (139), Expect = 8e-09
Identities = 40/104 (38%), Positives = 58/104 (55%), Gaps = 2/104 (1%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNN-FVQT 507
L+ LD+SKN L + + L+ L+ LNL SNKL +P ++ + KL ++++SNN Q
Sbjct: 125 LKYLDVSKNMLEKVVLIKNTLRSLEVLNLSSNKLWTVPTNMPS--KLHIVDLSNNSLTQI 182
Query: 506 LPVCLKNLNNLKQVYASNNKLQAFPKQILG-LQSLDVLDLSHNK 378
LP L NL NL +Y NNK P Q L L + L +N+
Sbjct: 183 LPGTLINLTNLTHLYLHNNKFTFIPDQSFDQLFQLQEITLYNNR 226
Score = 54.8 bits (126), Expect = 3e-07
Identities = 43/147 (29%), Positives = 81/147 (55%), Gaps = 2/147 (1%)
Frame = -2
Query: 734 DCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLIN 555
DC + + L + + +L+LS N + L + L++ +L+ L++ +N+L++LP L
Sbjct: 40 DCSGRNLSTLPSGLQENIIHLNLSYNHFTDLHNQLTQYTNLRTLDISNNRLESLPAHL-- 97
Query: 554 LKKLEVLNISNNFVQTLPVCLKNLN-NLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNK 378
+ L ++ +NN ++ L NLK + S N L+ L+SL+VL+LS NK
Sbjct: 98 PRSLWNMSAANNNIKLLDKSDTAYQWNLKYLDVSKNMLEKVVLIKNTLRSLEVLNLSSNK 157
Query: 377 ITEIPYGM-SELYVIELNLSQNEISLI 300
+ +P M S+L++++ LS N ++ I
Sbjct: 158 LWTVPTNMPSKLHIVD--LSNNSLTQI 182
>BC126171-1|AAI26172.1| 1119|Homo sapiens leucine-rich repeats and
immunoglobulin-like domains 3 protein.
Length = 1119
Score = 60.1 bits (139), Expect = 8e-09
Identities = 54/179 (30%), Positives = 92/179 (51%), Gaps = 8/179 (4%)
Frame = -2
Query: 683 LRNLDLSKNKL-SVLPDDLSKLKH-LKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQ 510
L+ L L+ N++ S+ P L + L L L+ N++ A+P + L +L+ L ++ N ++
Sbjct: 169 LKYLYLNSNRVTSMEPGYFDNLANTLLVLKLNRNRISAIPPKMFKLPQLQHLELNRNKIK 228
Query: 509 TLP-VCLKNLNNLKQVYASNNKL-QAFPKQILGLQSLDVLDLSHNKITEIPYG--MSELY 342
+ + + L LK + N + + GL ++++L L HN +TEI G L
Sbjct: 229 NVDGLTFQGLGALKSLKMQRNGVTKLMDGAFWGLSNMEILQLDHNNLTEITKGWLYGLLM 288
Query: 341 VIELNLSQNEISLIGEDLHQ-APRLKILRLDENCLS-LDEIKPSLLRDSKIHTVSVDGN 171
+ EL+LSQN I+ I D + +L L L N LS LD+ S L S ++T+ + N
Sbjct: 289 LQELHLSQNAINRISPDAWEFCQKLSELDLTFNHLSRLDD--SSFLGLSLLNTLHIGNN 345
Score = 58.8 bits (136), Expect = 2e-08
Identities = 45/172 (26%), Positives = 91/172 (52%), Gaps = 4/172 (2%)
Frame = -2
Query: 674 LDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALP-ESLINLKKLEVLNISNNFVQTLPV 498
LD S+ +L+ LP+ L + +L+L N+L + S+ +L+ L + ++NN ++T+P
Sbjct: 58 LDCSRKRLARLPEPLPSW--VARLDLSHNRLSFIKASSMSHLQSLREVKLNNNELETIPN 115
Query: 497 CLKNLNNLKQVYASNNKL-QAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVIELNLS 321
N+ + + N++ + P+ + QSL+ LDLS N I+E+ L + L L+
Sbjct: 116 LGPVSANITLLSLAGNRIVEILPEHLKEFQSLETLDLSSNNISELQTAFPALQLKYLYLN 175
Query: 320 QNEISLI--GEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIHTVSVDGN 171
N ++ + G + A L +L+L+ N +S I P + + ++ + ++ N
Sbjct: 176 SNRVTSMEPGYFDNLANTLLVLKLNRNRIS--AIPPKMFKLPQLQHLELNRN 225
>BC126169-1|AAI26170.1| 1119|Homo sapiens leucine-rich repeats and
immunoglobulin-like domains 3 protein.
Length = 1119
Score = 60.1 bits (139), Expect = 8e-09
Identities = 54/179 (30%), Positives = 92/179 (51%), Gaps = 8/179 (4%)
Frame = -2
Query: 683 LRNLDLSKNKL-SVLPDDLSKLKH-LKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQ 510
L+ L L+ N++ S+ P L + L L L+ N++ A+P + L +L+ L ++ N ++
Sbjct: 169 LKYLYLNSNRVTSMEPGYFDNLANTLLVLKLNRNRISAIPPKMFKLPQLQHLELNRNKIK 228
Query: 509 TLP-VCLKNLNNLKQVYASNNKL-QAFPKQILGLQSLDVLDLSHNKITEIPYG--MSELY 342
+ + + L LK + N + + GL ++++L L HN +TEI G L
Sbjct: 229 NVDGLTFQGLGALKSLKMQRNGVTKLMDGAFWGLSNMEILQLDHNNLTEITKGWLYGLLM 288
Query: 341 VIELNLSQNEISLIGEDLHQ-APRLKILRLDENCLS-LDEIKPSLLRDSKIHTVSVDGN 171
+ EL+LSQN I+ I D + +L L L N LS LD+ S L S ++T+ + N
Sbjct: 289 LQELHLSQNAINRISPDAWEFCQKLSELDLTFNHLSRLDD--SSFLGLSLLNTLHIGNN 345
Score = 58.8 bits (136), Expect = 2e-08
Identities = 45/172 (26%), Positives = 91/172 (52%), Gaps = 4/172 (2%)
Frame = -2
Query: 674 LDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALP-ESLINLKKLEVLNISNNFVQTLPV 498
LD S+ +L+ LP+ L + +L+L N+L + S+ +L+ L + ++NN ++T+P
Sbjct: 58 LDCSRKRLARLPEPLPSW--VARLDLSHNRLSFIKASSMSHLQSLREVKLNNNELETIPN 115
Query: 497 CLKNLNNLKQVYASNNKL-QAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVIELNLS 321
N+ + + N++ + P+ + QSL+ LDLS N I+E+ L + L L+
Sbjct: 116 LGPVSANITLLSLAGNRIVEILPEHLKEFQSLETLDLSSNNISELQTAFPALQLKYLYLN 175
Query: 320 QNEISLI--GEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIHTVSVDGN 171
N ++ + G + A L +L+L+ N +S I P + + ++ + ++ N
Sbjct: 176 SNRVTSMEPGYFDNLANTLLVLKLNRNRIS--AIPPKMFKLPQLQHLELNRN 225
>BC082244-1|AAH82244.1| 465|Homo sapiens PHLPP protein protein.
Length = 465
Score = 60.1 bits (139), Expect = 8e-09
Identities = 36/107 (33%), Positives = 65/107 (60%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTL 504
L+ L S N+L L D +L +++ N+L+ +PE + +KLEVL+I +N + L
Sbjct: 98 LKALYASSNELVQL-DVYPVPNYLSYMDVSRNRLENVPEWVCESRKLEVLDIGHNQICEL 156
Query: 503 PVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIP 363
P L ++L+++ A +N+L P++ L S++VLD+ HN++ E+P
Sbjct: 157 PARLFCNSSLRKLLAGHNQLARLPER-LERTSVEVLDVQHNQLLELP 202
Score = 56.4 bits (130), Expect = 1e-07
Identities = 57/203 (28%), Positives = 101/203 (49%), Gaps = 22/203 (10%)
Frame = -2
Query: 683 LRNLDLSKNKL-SVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQT 507
++++DL N + ++ D++ L+H+ QL+L NKL L + N +EVL+ N + T
Sbjct: 33 IKHVDLRLNVIRKLIADEVDFLQHVTQLDLRDNKLGDLDAMIFN--NIEVLHCERNQLVT 90
Query: 506 LPVC---LKNL----NNLKQ--VY----------ASNNKLQAFPKQILGLQSLDVLDLSH 384
L +C LK L N L Q VY S N+L+ P+ + + L+VLD+ H
Sbjct: 91 LDICGYFLKALYASSNELVQLDVYPVPNYLSYMDVSRNRLENVPEWVCESRKLEVLDIGH 150
Query: 383 NKITEIPYGM-SELYVIELNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLL- 210
N+I E+P + + +L N+++ + E L + +++L + N L E+ P+LL
Sbjct: 151 NQICELPARLFCNSSLRKLLAGHNQLARLPERLERT-SVEVLDVQHN--QLLELPPNLLM 207
Query: 209 RDSKIHTVSVDGNLFEPKQLAXL 141
+ + ++ N E A L
Sbjct: 208 KADSLRFLNASANKLESLPPATL 230
Score = 56.0 bits (129), Expect = 1e-07
Identities = 50/167 (29%), Positives = 86/167 (51%), Gaps = 6/167 (3%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPD-DLSKLKH--LKQLNLDSNKL--QALPES 564
+L E+P ++ D LR L+ S NKL LP LS+ + L++L L +N L + +P
Sbjct: 197 QLLELPPNLLMKADSLRFLNASANKLESLPPATLSEETNSILQELYLTNNSLTDKCVP-L 255
Query: 563 LINLKKLEVLNISNNFVQTLPVC-LKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLS 387
L L++L+++ N +Q+ P + L L+++ S NKL+A P I+ + + +
Sbjct: 256 LTGHPHLKILHMAYNRLQSFPASKMAKLEELEEIDLSGNKLKAIPTTIMNCRRMHTVIAH 315
Query: 386 HNKITEIPYGMSELYVIELNLSQNEISLIGEDLHQAPRLKILRLDEN 246
N I P M + ++LS NE+S + + P+L+ L L N
Sbjct: 316 SNCIEVFPEVMQLPEIKCVDLSCNELSEVTLPENLPPKLQELDLTGN 362
Score = 49.2 bits (112), Expect = 2e-05
Identities = 49/188 (26%), Positives = 89/188 (47%), Gaps = 6/188 (3%)
Frame = -2
Query: 716 IPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEV 537
+ +DV+ + + L +D+S+N+L +P+ + + + L+ L++ N++ LP L L
Sbjct: 109 VQLDVYPVPNYLSYMDVSRNRLENVPEWVCESRKLEVLDIGHNQICELPARLFCNSSLRK 168
Query: 536 LNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYG 357
L +N + LP L+ + N L+ P ++ SL L+ S NK+ +P
Sbjct: 169 LLAGHNQLARLPERLERTSVEVLDVQHNQLLELPPNLLMKADSLRFLNASANKLESLPPA 228
Query: 356 -MSE---LYVIELNLSQNEIS-LIGEDLHQAPRLKILRLDENCL-SLDEIKPSLLRDSKI 195
+SE + EL L+ N ++ L P LKIL + N L S K + L + +
Sbjct: 229 TLSEETNSILQELYLTNNSLTDKCVPLLTGHPHLKILHMAYNRLQSFPASKMAKLEE--L 286
Query: 194 HTVSVDGN 171
+ + GN
Sbjct: 287 EEIDLSGN 294
>BC045113-1|AAH45113.1| 522|Homo sapiens LRRTM1 protein protein.
Length = 522
Score = 60.1 bits (139), Expect = 8e-09
Identities = 55/196 (28%), Positives = 103/196 (52%), Gaps = 7/196 (3%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVL-PDDLSKLKHLKQLNLDSNKLQALPESLI-N 555
++ ++P F LR++DLS NKL L PD L+ L L++ +N +Q +P + +
Sbjct: 124 QITQLPNTTFRPMPNLRSVDLSYNKLQALAPDLFHGLRKLTTLHMRANAIQFVPVRIFQD 183
Query: 554 LKKLEVLNISNNFVQTLP-VCLKNLNNLKQVYASNNKL-QAFPKQILGLQSLDVLDLSHN 381
+ L+ L+I N +++L L L +++ +N L + L SL L L N
Sbjct: 184 CRSLKFLDIGYNQLKSLARNSFAGLFKLTELHLEHNDLVKVNFAHFPRLISLHSLCLRRN 243
Query: 380 KITEIPYGMSELYVIE-LNLSQNEISLIGEDLHQ-APRLKILRLDENCLSLDEIKPSLLR 207
K+ + + ++ +E ++LS NEI + + + P L+ L+LD N L+ I+P +L
Sbjct: 244 KVAIVVSSLDWVWNLEKMDLSGNEIEYMEPHVFETVPHLQSLQLDSNRLTY--IEPRILN 301
Query: 206 DSK-IHTVSVDGNLFE 162
K + ++++ GNL++
Sbjct: 302 SWKSLTSITLAGNLWD 317
Score = 44.0 bits (99), Expect = 6e-04
Identities = 36/111 (32%), Positives = 55/111 (49%), Gaps = 4/111 (3%)
Frame = -2
Query: 683 LRNLDLSKNKLSVL-PDDLSKLKHLKQLNLDSNKLQALP-ESLINLKKLEVLNISNNFVQ 510
L L L N LS L + L L L LD N + ++ ++ L++++ L +S+N +
Sbjct: 67 LLGLSLRYNSLSELRAGQFTGLMQLTWLYLDHNHICSVQGDAFQKLRRVKELTLSSNQIT 126
Query: 509 TLP-VCLKNLNNLKQVYASNNKLQAF-PKQILGLQSLDVLDLSHNKITEIP 363
LP + + NL+ V S NKLQA P GL+ L L + N I +P
Sbjct: 127 QLPNTTFRPMPNLRSVDLSYNKLQALAPDLFHGLRKLTTLHMRANAIQFVP 177
>BC018050-1|AAH18050.1| 440|Homo sapiens oligodendrocyte myelin
glycoprotein protein.
Length = 440
Score = 60.1 bits (139), Expect = 8e-09
Identities = 40/104 (38%), Positives = 58/104 (55%), Gaps = 2/104 (1%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNN-FVQT 507
L+ LD+SKN L + + L+ L+ LNL SNKL +P ++ + KL ++++SNN Q
Sbjct: 125 LKYLDVSKNMLEKVVLIKNTLRSLEVLNLSSNKLWTVPTNMPS--KLHIVDLSNNSLTQI 182
Query: 506 LPVCLKNLNNLKQVYASNNKLQAFPKQILG-LQSLDVLDLSHNK 378
LP L NL NL +Y NNK P Q L L + L +N+
Sbjct: 183 LPGTLINLTNLTHLYLHNNKFTFIPDQSFDQLFQLQEITLYNNR 226
Score = 54.8 bits (126), Expect = 3e-07
Identities = 43/147 (29%), Positives = 81/147 (55%), Gaps = 2/147 (1%)
Frame = -2
Query: 734 DCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLIN 555
DC + + L + + +L+LS N + L + L++ +L+ L++ +N+L++LP L
Sbjct: 40 DCSGRNLSTLPSGLQENIIHLNLSYNHFTDLHNQLTQYTNLRTLDISNNRLESLPAHL-- 97
Query: 554 LKKLEVLNISNNFVQTLPVCLKNLN-NLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNK 378
+ L ++ +NN ++ L NLK + S N L+ L+SL+VL+LS NK
Sbjct: 98 PRSLWNMSAANNNIKLLDKSDTAYQWNLKYLDVSKNMLEKVVLIKNTLRSLEVLNLSSNK 157
Query: 377 ITEIPYGM-SELYVIELNLSQNEISLI 300
+ +P M S+L++++ LS N ++ I
Sbjct: 158 LWTVPTNMPSKLHIVD--LSNNSLTQI 182
>AY505340-1|AAR98629.1| 1119|Homo sapiens leucine-rich and
immunoglobulin-like domains 3 protein.
Length = 1119
Score = 60.1 bits (139), Expect = 8e-09
Identities = 54/179 (30%), Positives = 92/179 (51%), Gaps = 8/179 (4%)
Frame = -2
Query: 683 LRNLDLSKNKL-SVLPDDLSKLKH-LKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQ 510
L+ L L+ N++ S+ P L + L L L+ N++ A+P + L +L+ L ++ N ++
Sbjct: 169 LKYLYLNSNRVTSMEPGYFDNLANTLLVLKLNRNRISAIPPKMFKLPQLQHLELNRNKIK 228
Query: 509 TLP-VCLKNLNNLKQVYASNNKL-QAFPKQILGLQSLDVLDLSHNKITEIPYG--MSELY 342
+ + + L LK + N + + GL ++++L L HN +TEI G L
Sbjct: 229 NVDGLTFQGLGALKSLKMQRNGVTKLMDGAFWGLSNMEILQLDHNNLTEITKGWLYGLLM 288
Query: 341 VIELNLSQNEISLIGEDLHQ-APRLKILRLDENCLS-LDEIKPSLLRDSKIHTVSVDGN 171
+ EL+LSQN I+ I D + +L L L N LS LD+ S L S ++T+ + N
Sbjct: 289 LQELHLSQNAINRISPDAWEFCQKLSELDLTFNHLSRLDD--SSFLGLSLLNTLHIGNN 345
Score = 58.8 bits (136), Expect = 2e-08
Identities = 45/172 (26%), Positives = 91/172 (52%), Gaps = 4/172 (2%)
Frame = -2
Query: 674 LDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALP-ESLINLKKLEVLNISNNFVQTLPV 498
LD S+ +L+ LP+ L + +L+L N+L + S+ +L+ L + ++NN ++T+P
Sbjct: 58 LDCSRKRLARLPEPLPSW--VARLDLSHNRLSFIKASSMSHLQSLREVKLNNNELETIPN 115
Query: 497 CLKNLNNLKQVYASNNKL-QAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVIELNLS 321
N+ + + N++ + P+ + QSL+ LDLS N I+E+ L + L L+
Sbjct: 116 LGPVSANITLLSLAGNRIVEILPEHLKEFQSLETLDLSSNNISELQTAFPALQLKYLYLN 175
Query: 320 QNEISLI--GEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIHTVSVDGN 171
N ++ + G + A L +L+L+ N +S I P + + ++ + ++ N
Sbjct: 176 SNRVTSMEPGYFDNLANTLLVLKLNRNRIS--AIPPKMFKLPQLQHLELNRN 225
>AY358310-1|AAQ88677.1| 522|Homo sapiens DFLL675 protein.
Length = 522
Score = 60.1 bits (139), Expect = 8e-09
Identities = 55/196 (28%), Positives = 103/196 (52%), Gaps = 7/196 (3%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVL-PDDLSKLKHLKQLNLDSNKLQALPESLI-N 555
++ ++P F LR++DLS NKL L PD L+ L L++ +N +Q +P + +
Sbjct: 124 QITQLPNTTFRPMPNLRSVDLSYNKLQALAPDLFHGLRKLTTLHMRANAIQFVPVRIFQD 183
Query: 554 LKKLEVLNISNNFVQTLP-VCLKNLNNLKQVYASNNKL-QAFPKQILGLQSLDVLDLSHN 381
+ L+ L+I N +++L L L +++ +N L + L SL L L N
Sbjct: 184 CRSLKFLDIGYNQLKSLARNSFAGLFKLTELHLEHNDLVKVNFAHFPRLISLHSLCLRRN 243
Query: 380 KITEIPYGMSELYVIE-LNLSQNEISLIGEDLHQ-APRLKILRLDENCLSLDEIKPSLLR 207
K+ + + ++ +E ++LS NEI + + + P L+ L+LD N L+ I+P +L
Sbjct: 244 KVAIVVSSLDWVWNLEKMDLSGNEIEYMEPHVFETVPHLQSLQLDSNRLTY--IEPRILN 301
Query: 206 DSK-IHTVSVDGNLFE 162
K + ++++ GNL++
Sbjct: 302 SWKSLTSITLAGNLWD 317
Score = 44.0 bits (99), Expect = 6e-04
Identities = 36/111 (32%), Positives = 55/111 (49%), Gaps = 4/111 (3%)
Frame = -2
Query: 683 LRNLDLSKNKLSVL-PDDLSKLKHLKQLNLDSNKLQALP-ESLINLKKLEVLNISNNFVQ 510
L L L N LS L + L L L LD N + ++ ++ L++++ L +S+N +
Sbjct: 67 LLGLSLRYNSLSELRAGQFTGLMQLTWLYLDHNHICSVQGDAFQKLRRVKELTLSSNQIT 126
Query: 509 TLP-VCLKNLNNLKQVYASNNKLQAF-PKQILGLQSLDVLDLSHNKITEIP 363
LP + + NL+ V S NKLQA P GL+ L L + N I +P
Sbjct: 127 QLPNTTFRPMPNLRSVDLSYNKLQALAPDLFHGLRKLTTLHMRANAIQFVP 177
>AY358295-1|AAQ88662.1| 1059|Homo sapiens SAPS287 protein.
Length = 1059
Score = 60.1 bits (139), Expect = 8e-09
Identities = 54/179 (30%), Positives = 92/179 (51%), Gaps = 8/179 (4%)
Frame = -2
Query: 683 LRNLDLSKNKL-SVLPDDLSKLKH-LKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQ 510
L+ L L+ N++ S+ P L + L L L+ N++ A+P + L +L+ L ++ N ++
Sbjct: 109 LKYLYLNSNRVTSMEPGYFDNLANTLLVLKLNRNRISAIPPKMFKLPQLQHLELNRNKIK 168
Query: 509 TLP-VCLKNLNNLKQVYASNNKL-QAFPKQILGLQSLDVLDLSHNKITEIPYG--MSELY 342
+ + + L LK + N + + GL ++++L L HN +TEI G L
Sbjct: 169 NVDGLTFQGLGALKSLKMQRNGVTKLMDGAFWGLSNMEILQLDHNNLTEITKGWLYGLLM 228
Query: 341 VIELNLSQNEISLIGEDLHQ-APRLKILRLDENCLS-LDEIKPSLLRDSKIHTVSVDGN 171
+ EL+LSQN I+ I D + +L L L N LS LD+ S L S ++T+ + N
Sbjct: 229 LQELHLSQNAINRISPDAWEFCQKLSELDLTFNHLSRLDD--SSFLGLSLLNTLHIGNN 285
Score = 53.2 bits (122), Expect = 9e-07
Identities = 40/158 (25%), Positives = 82/158 (51%), Gaps = 4/158 (2%)
Frame = -2
Query: 632 LSKLKHLKQLNLDSNKLQALP-ESLINLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYAS 456
L L H+ + +L N+L + S+ +L+ L + ++NN ++T+P N+ + +
Sbjct: 10 LCLLFHISRPDLSHNRLSFIKASSMSHLQSLREVKLNNNELETIPNLGPVSANITLLSLA 69
Query: 455 NNKL-QAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVIELNLSQNEISLI--GEDLH 285
N++ + P+ + QSL+ LDLS N I+E+ L + L L+ N ++ + G +
Sbjct: 70 GNRIVEILPEHLKEFQSLETLDLSSNNISELQTAFPALQLKYLYLNSNRVTSMEPGYFDN 129
Query: 284 QAPRLKILRLDENCLSLDEIKPSLLRDSKIHTVSVDGN 171
A L +L+L+ N +S I P + + ++ + ++ N
Sbjct: 130 LANTLLVLKLNRNRIS--AIPPKMFKLPQLQHLELNRN 165
>AY358288-1|AAQ88655.1| 1119|Homo sapiens SAPS287 protein.
Length = 1119
Score = 60.1 bits (139), Expect = 8e-09
Identities = 54/179 (30%), Positives = 92/179 (51%), Gaps = 8/179 (4%)
Frame = -2
Query: 683 LRNLDLSKNKL-SVLPDDLSKLKH-LKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQ 510
L+ L L+ N++ S+ P L + L L L+ N++ A+P + L +L+ L ++ N ++
Sbjct: 169 LKYLYLNSNRVTSMEPGYFDNLANTLLVLKLNRNRISAIPPKMFKLPQLQHLELNRNKIK 228
Query: 509 TLP-VCLKNLNNLKQVYASNNKL-QAFPKQILGLQSLDVLDLSHNKITEIPYG--MSELY 342
+ + + L LK + N + + GL ++++L L HN +TEI G L
Sbjct: 229 NVDGLTFQGLGALKSLKMQRNGVTKLMDGAFWGLSNMEILQLDHNNLTEITKGWLYGLLM 288
Query: 341 VIELNLSQNEISLIGEDLHQ-APRLKILRLDENCLS-LDEIKPSLLRDSKIHTVSVDGN 171
+ EL+LSQN I+ I D + +L L L N LS LD+ S L S ++T+ + N
Sbjct: 289 LQELHLSQNAINRISPDAWEFCQKLSELDLTFNHLSRLDD--SSFLGLSLLNTLHIGNN 345
Score = 58.8 bits (136), Expect = 2e-08
Identities = 45/172 (26%), Positives = 91/172 (52%), Gaps = 4/172 (2%)
Frame = -2
Query: 674 LDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALP-ESLINLKKLEVLNISNNFVQTLPV 498
LD S+ +L+ LP+ L + +L+L N+L + S+ +L+ L + ++NN ++T+P
Sbjct: 58 LDCSRKRLARLPEPLPSW--VARLDLSHNRLSFIKASSMSHLQSLREVKLNNNELETIPN 115
Query: 497 CLKNLNNLKQVYASNNKL-QAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVIELNLS 321
N+ + + N++ + P+ + QSL+ LDLS N I+E+ L + L L+
Sbjct: 116 LGPVSANITLLSLAGNRIVEILPEHLKEFQSLETLDLSSNNISELQTAFPALQLKYLYLN 175
Query: 320 QNEISLI--GEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIHTVSVDGN 171
N ++ + G + A L +L+L+ N +S I P + + ++ + ++ N
Sbjct: 176 SNRVTSMEPGYFDNLANTLLVLKLNRNRIS--AIPPKMFKLPQLQHLELNRN 225
>AY182024-1|AAO67545.1| 522|Homo sapiens leucine-rich repeat
transmembrane neuronal 1 protein protein.
Length = 522
Score = 60.1 bits (139), Expect = 8e-09
Identities = 55/196 (28%), Positives = 103/196 (52%), Gaps = 7/196 (3%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVL-PDDLSKLKHLKQLNLDSNKLQALPESLI-N 555
++ ++P F LR++DLS NKL L PD L+ L L++ +N +Q +P + +
Sbjct: 124 QITQLPNTTFRPMPNLRSVDLSYNKLQALAPDLFHGLRKLTTLHMRANAIQFVPVRIFQD 183
Query: 554 LKKLEVLNISNNFVQTLP-VCLKNLNNLKQVYASNNKL-QAFPKQILGLQSLDVLDLSHN 381
+ L+ L+I N +++L L L +++ +N L + L SL L L N
Sbjct: 184 CRSLKFLDIGYNQLKSLARNSFAGLFKLTELHLEHNDLVKVNFAHFPRLISLHSLCLRRN 243
Query: 380 KITEIPYGMSELYVIE-LNLSQNEISLIGEDLHQ-APRLKILRLDENCLSLDEIKPSLLR 207
K+ + + ++ +E ++LS NEI + + + P L+ L+LD N L+ I+P +L
Sbjct: 244 KVAIVVSSLDWVWNLEKMDLSGNEIEYMEPHVFETVPHLQSLQLDSNRLTY--IEPRILN 301
Query: 206 DSK-IHTVSVDGNLFE 162
K + ++++ GNL++
Sbjct: 302 SWKSLTSITLAGNLWD 317
Score = 44.0 bits (99), Expect = 6e-04
Identities = 36/111 (32%), Positives = 55/111 (49%), Gaps = 4/111 (3%)
Frame = -2
Query: 683 LRNLDLSKNKLSVL-PDDLSKLKHLKQLNLDSNKLQALP-ESLINLKKLEVLNISNNFVQ 510
L L L N LS L + L L L LD N + ++ ++ L++++ L +S+N +
Sbjct: 67 LLGLSLRYNSLSELRAGQFTGLMQLTWLYLDHNHICSVQGDAFQKLRRVKELTLSSNQIT 126
Query: 509 TLP-VCLKNLNNLKQVYASNNKLQAF-PKQILGLQSLDVLDLSHNKITEIP 363
LP + + NL+ V S NKLQA P GL+ L L + N I +P
Sbjct: 127 QLPNTTFRPMPNLRSVDLSYNKLQALAPDLFHGLRKLTTLHMRANAIQFVP 177
>AK222663-1|BAD96383.1| 440|Homo sapiens oligodendrocyte myelin
glycoprotein variant protein.
Length = 440
Score = 60.1 bits (139), Expect = 8e-09
Identities = 40/104 (38%), Positives = 58/104 (55%), Gaps = 2/104 (1%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNN-FVQT 507
L+ LD+SKN L + + L+ L+ LNL SNKL +P ++ + KL ++++SNN Q
Sbjct: 125 LKYLDVSKNMLEKVVLIKNTLRSLEVLNLSSNKLWTVPTNMPS--KLHIVDLSNNSLTQI 182
Query: 506 LPVCLKNLNNLKQVYASNNKLQAFPKQILG-LQSLDVLDLSHNK 378
LP L NL NL +Y NNK P Q L L + L +N+
Sbjct: 183 LPGTLINLTNLTHLYLHNNKFTFIPDQSFDQLFQLQEITLYNNR 226
Score = 54.8 bits (126), Expect = 3e-07
Identities = 43/147 (29%), Positives = 81/147 (55%), Gaps = 2/147 (1%)
Frame = -2
Query: 734 DCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLIN 555
DC + + L + + +L+LS N + L + L++ +L+ L++ +N+L++LP L
Sbjct: 40 DCSGRNLSTLPSGLQENIIHLNLSYNHFTDLHNQLTQYTNLRTLDISNNRLESLPAHL-- 97
Query: 554 LKKLEVLNISNNFVQTLPVCLKNLN-NLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNK 378
+ L ++ +NN ++ L NLK + S N L+ L+SL+VL+LS NK
Sbjct: 98 PRSLWNMSAANNNIKLLDKSDTAYQWNLKYLDVSKNMLEKVVLIKNTLRSLEVLNLSSNK 157
Query: 377 ITEIPYGM-SELYVIELNLSQNEISLI 300
+ +P M S+L++++ LS N ++ I
Sbjct: 158 LWTVPTNMPSKLHIVD--LSNNSLTQI 182
>AK056644-1|BAB71240.1| 522|Homo sapiens protein ( Homo sapiens
cDNA FLJ32082 fis, clone OCBBF2000231, weakly similar to
PHOSPHOLIPASE A2 INHIBITOR SUBUNIT B PRECURSOR. ).
Length = 522
Score = 60.1 bits (139), Expect = 8e-09
Identities = 55/196 (28%), Positives = 103/196 (52%), Gaps = 7/196 (3%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVL-PDDLSKLKHLKQLNLDSNKLQALPESLI-N 555
++ ++P F LR++DLS NKL L PD L+ L L++ +N +Q +P + +
Sbjct: 124 QITQLPNTTFRPMPNLRSVDLSYNKLQALAPDLFHGLRKLTTLHMRANAIQFVPVRIFQD 183
Query: 554 LKKLEVLNISNNFVQTLP-VCLKNLNNLKQVYASNNKL-QAFPKQILGLQSLDVLDLSHN 381
+ L+ L+I N +++L L L +++ +N L + L SL L L N
Sbjct: 184 CRSLKFLDIGYNQLKSLARNSFAGLFKLTELHLEHNDLVKVNFAHFPRLISLHSLCLRRN 243
Query: 380 KITEIPYGMSELYVIE-LNLSQNEISLIGEDLHQ-APRLKILRLDENCLSLDEIKPSLLR 207
K+ + + ++ +E ++LS NEI + + + P L+ L+LD N L+ I+P +L
Sbjct: 244 KVAIVVSSLDWVWNLEKMDLSGNEIEYMEPHVFETVPHLQSLQLDSNRLTY--IEPRILN 301
Query: 206 DSK-IHTVSVDGNLFE 162
K + ++++ GNL++
Sbjct: 302 SWKSLTSITLAGNLWD 317
Score = 44.0 bits (99), Expect = 6e-04
Identities = 36/111 (32%), Positives = 55/111 (49%), Gaps = 4/111 (3%)
Frame = -2
Query: 683 LRNLDLSKNKLSVL-PDDLSKLKHLKQLNLDSNKLQALP-ESLINLKKLEVLNISNNFVQ 510
L L L N LS L + L L L LD N + ++ ++ L++++ L +S+N +
Sbjct: 67 LLGLSLRYNSLSELRAGQFTGLMQLTWLYLDHNHICSVQGDAFQKLRRVKELTLSSNQIT 126
Query: 509 TLP-VCLKNLNNLKQVYASNNKLQAF-PKQILGLQSLDVLDLSHNKITEIP 363
LP + + NL+ V S NKLQA P GL+ L L + N I +P
Sbjct: 127 QLPNTTFRPMPNLRSVDLSYNKLQALAPDLFHGLRKLTTLHMRANAIQFVP 177
>BC031301-1|AAH31301.1| 583|Homo sapiens leucine rich repeat
containing 47 protein.
Length = 583
Score = 59.7 bits (138), Expect = 1e-08
Identities = 46/137 (33%), Positives = 72/137 (52%), Gaps = 12/137 (8%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPD-------DLSKLKHLKQLNLDSNKLQALPESLINLK-KLEVLNI 528
LR LDLS N L LP + L L+ LNL N+L+ LP L +L+ LN+
Sbjct: 101 LRVLDLSGNALEALPPGQGLGPAEPPGLPQLQSLNLSGNRLRELPADLARCAPRLQSLNL 160
Query: 527 SNNFVQTLPVCLKN---LNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYG 357
+ N + + P L L L ++ A++N L+ I L SL LDLS+N+++EIP
Sbjct: 161 TGNCLDSFPAELFRPGALPLLSELAAADNCLRELSPDIAHLASLKTLDLSNNQLSEIPAE 220
Query: 356 MSELYVI-ELNLSQNEI 309
+++ + E+N N++
Sbjct: 221 LADCPKLKEINFRGNKL 237
Score = 52.0 bits (119), Expect = 2e-06
Identities = 34/117 (29%), Positives = 61/117 (52%), Gaps = 5/117 (4%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSK---LKHLKQLNLDSNKLQALPESLI 558
+L+E+P D+ L++L+L+ N L P +L + L L +L N L+ L +
Sbjct: 140 RLRELPADLARCAPRLQSLNLTGNCLDSFPAELFRPGALPLLSELAAADNCLRELSPDIA 199
Query: 557 NLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKL--QAFPKQILGLQSLDVLD 393
+L L+ L++SNN + +P L + LK++ NKL + K + G Q+ +L+
Sbjct: 200 HLASLKTLDLSNNQLSEIPAELADCPKLKEINFRGNKLRDKRLEKMVSGCQTRSILE 256
Score = 50.8 bits (116), Expect = 5e-06
Identities = 34/109 (31%), Positives = 57/109 (52%), Gaps = 4/109 (3%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLK-HLKQLNLDSNKLQALPESLIN---LKKLEVLNISNNF 516
L++L+LS N+L LP DL++ L+ LNL N L + P L L L L ++N
Sbjct: 131 LQSLNLSGNRLRELPADLARCAPRLQSLNLTGNCLDSFPAELFRPGALPLLSELAAADNC 190
Query: 515 VQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITE 369
++ L + +L +LK + SNN+L P ++ L ++ NK+ +
Sbjct: 191 LRELSPDIAHLASLKTLDLSNNQLSEIPAELADCPKLKEINFRGNKLRD 239
Score = 41.1 bits (92), Expect = 0.004
Identities = 22/53 (41%), Positives = 33/53 (62%)
Frame = -2
Query: 737 ADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQ 579
AD L+E+ D+ L L+ LDLS N+LS +P +L+ LK++N NKL+
Sbjct: 187 ADNCLRELSPDIAHLAS-LKTLDLSNNQLSEIPAELADCPKLKEINFRGNKLR 238
Score = 36.3 bits (80), Expect = 0.12
Identities = 45/143 (31%), Positives = 60/143 (41%), Gaps = 12/143 (8%)
Frame = -2
Query: 575 LPESLINLKKLEVLNISN--NFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILG-LQSL 405
LP L L L L +S + P + L L + N L LG L +L
Sbjct: 42 LPPRLFTLPLLHYLEVSGCGSLRAPGPGLAQGLPQLHSLVLRRNALGPGLSPELGPLPAL 101
Query: 404 DVLDLSHNKITEIPYGMS-------ELYVIE-LNLSQNEISLIGEDLHQ-APRLKILRLD 252
VLDLS N + +P G L ++ LNLS N + + DL + APRL+ L L
Sbjct: 102 RVLDLSGNALEALPPGQGLGPAEPPGLPQLQSLNLSGNRLRELPADLARCAPRLQSLNLT 161
Query: 251 ENCLSLDEIKPSLLRDSKIHTVS 183
NC LD L R + +S
Sbjct: 162 GNC--LDSFPAELFRPGALPLLS 182
>AL365330-3|CAI42528.1| 583|Homo sapiens leucine rich repeat
containing 47 protein.
Length = 583
Score = 59.7 bits (138), Expect = 1e-08
Identities = 46/137 (33%), Positives = 72/137 (52%), Gaps = 12/137 (8%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPD-------DLSKLKHLKQLNLDSNKLQALPESLINLK-KLEVLNI 528
LR LDLS N L LP + L L+ LNL N+L+ LP L +L+ LN+
Sbjct: 101 LRVLDLSGNALEALPPGQGLGPAEPPGLPQLQSLNLSGNRLRELPADLARCAPRLQSLNL 160
Query: 527 SNNFVQTLPVCLKN---LNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYG 357
+ N + + P L L L ++ A++N L+ I L SL LDLS+N+++EIP
Sbjct: 161 TGNCLDSFPAELFRPGALPLLSELAAADNCLRELSPDIAHLASLKTLDLSNNQLSEIPAE 220
Query: 356 MSELYVI-ELNLSQNEI 309
+++ + E+N N++
Sbjct: 221 LADCPKLKEINFRGNKL 237
Score = 52.0 bits (119), Expect = 2e-06
Identities = 34/117 (29%), Positives = 61/117 (52%), Gaps = 5/117 (4%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSK---LKHLKQLNLDSNKLQALPESLI 558
+L+E+P D+ L++L+L+ N L P +L + L L +L N L+ L +
Sbjct: 140 RLRELPADLARCAPRLQSLNLTGNCLDSFPAELFRPGALPLLSELAAADNCLRELSPDIA 199
Query: 557 NLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKL--QAFPKQILGLQSLDVLD 393
+L L+ L++SNN + +P L + LK++ NKL + K + G Q+ +L+
Sbjct: 200 HLASLKTLDLSNNQLSEIPAELADCPKLKEINFRGNKLRDKRLEKMVSGCQTRSILE 256
Score = 50.8 bits (116), Expect = 5e-06
Identities = 34/109 (31%), Positives = 57/109 (52%), Gaps = 4/109 (3%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLK-HLKQLNLDSNKLQALPESLIN---LKKLEVLNISNNF 516
L++L+LS N+L LP DL++ L+ LNL N L + P L L L L ++N
Sbjct: 131 LQSLNLSGNRLRELPADLARCAPRLQSLNLTGNCLDSFPAELFRPGALPLLSELAAADNC 190
Query: 515 VQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITE 369
++ L + +L +LK + SNN+L P ++ L ++ NK+ +
Sbjct: 191 LRELSPDIAHLASLKTLDLSNNQLSEIPAELADCPKLKEINFRGNKLRD 239
Score = 41.1 bits (92), Expect = 0.004
Identities = 22/53 (41%), Positives = 33/53 (62%)
Frame = -2
Query: 737 ADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQ 579
AD L+E+ D+ L L+ LDLS N+LS +P +L+ LK++N NKL+
Sbjct: 187 ADNCLRELSPDIAHLAS-LKTLDLSNNQLSEIPAELADCPKLKEINFRGNKLR 238
Score = 36.3 bits (80), Expect = 0.12
Identities = 45/143 (31%), Positives = 60/143 (41%), Gaps = 12/143 (8%)
Frame = -2
Query: 575 LPESLINLKKLEVLNISN--NFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILG-LQSL 405
LP L L L L +S + P + L L + N L LG L +L
Sbjct: 42 LPPRLFTLPLLHYLEVSGCGSLRAPGPGLAQGLPQLHSLVLRRNALGPGLSPELGPLPAL 101
Query: 404 DVLDLSHNKITEIPYGMS-------ELYVIE-LNLSQNEISLIGEDLHQ-APRLKILRLD 252
VLDLS N + +P G L ++ LNLS N + + DL + APRL+ L L
Sbjct: 102 RVLDLSGNALEALPPGQGLGPAEPPGLPQLQSLNLSGNRLRELPADLARCAPRLQSLNLT 161
Query: 251 ENCLSLDEIKPSLLRDSKIHTVS 183
NC LD L R + +S
Sbjct: 162 GNC--LDSFPAELFRPGALPLLS 182
>M22403-1|AAA52596.1| 626|Homo sapiens platelet membrane
glycoprotein Ib-alpha protein.
Length = 626
Score = 59.3 bits (137), Expect = 1e-08
Identities = 45/128 (35%), Positives = 68/128 (53%), Gaps = 3/128 (2%)
Frame = -2
Query: 731 CKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALP-ESLIN 555
C+L ++ +D VL LDLS N+L LP L L L++ N+L +LP +L
Sbjct: 81 CELTKLQVD--GTLPVLGTLDLSHNQLQSLPLLGQTLPALTVLDVSFNRLTSLPLGALRG 138
Query: 554 LKKLEVLNISNNFVQTLPV-CLKNLNNLKQVYASNNKLQAFPKQIL-GLQSLDVLDLSHN 381
L +L+ L + N ++TLP L L+++ +NN L P +L GL++LD L L N
Sbjct: 139 LGELQELYLKGNELKTLPPGLLTPTPKLEKLSLANNNLTELPAGLLNGLENLDTLLLQEN 198
Query: 380 KITEIPYG 357
+ IP G
Sbjct: 199 SLYTIPKG 206
Score = 52.8 bits (121), Expect = 1e-06
Identities = 41/119 (34%), Positives = 59/119 (49%), Gaps = 3/119 (2%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLP-DDLSKLKHLKQLNLDSNKLQALPESLIN- 555
+L+ +P+ + L LD+S N+L+ LP L L L++L L N+L+ LP L+
Sbjct: 104 QLQSLPL-LGQTLPALTVLDVSFNRLTSLPLGALRGLGELQELYLKGNELKTLPPGLLTP 162
Query: 554 LKKLEVLNISNNFVQTLPVCLKN-LNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHN 381
KLE L+++NN + LP L N L NL + N L PK G L L N
Sbjct: 163 TPKLEKLSLANNNLTELPAGLLNGLENLDTLLLQENSLYTIPKGFFGSHLLPFAFLHGN 221
Score = 46.8 bits (106), Expect = 8e-05
Identities = 54/179 (30%), Positives = 84/179 (46%), Gaps = 11/179 (6%)
Frame = -2
Query: 713 PIDVFSLCDVLR-----NLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALP-ESLINL 552
P+ +C+V + ++ K L+ LP DL K + L+L N L +L+
Sbjct: 13 PLHPHPICEVSKVASHLEVNCDKRNLTALPPDLPKDTTI--LHLSENLLYTFSLATLMPY 70
Query: 551 KKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKIT 372
+L LN+ + L V L L + S+N+LQ+ P L +L VLD+S N++T
Sbjct: 71 TRLTQLNLDRCELTKLQVD-GTLPVLGTLDLSHNQLQSLPLLGQTLPALTVLDVSFNRLT 129
Query: 371 EIPY----GMSELYVIELNLSQNEISLIGED-LHQAPRLKILRLDENCLSLDEIKPSLL 210
+P G+ EL EL L NE+ + L P+L+ L L N +L E+ LL
Sbjct: 130 SLPLGALRGLGELQ--ELYLKGNELKTLPPGLLTPTPKLEKLSLANN--NLTELPAGLL 184
>J02940-1|AAA52595.1| 626|Homo sapiens GP1BA protein.
Length = 626
Score = 59.3 bits (137), Expect = 1e-08
Identities = 45/128 (35%), Positives = 68/128 (53%), Gaps = 3/128 (2%)
Frame = -2
Query: 731 CKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALP-ESLIN 555
C+L ++ +D VL LDLS N+L LP L L L++ N+L +LP +L
Sbjct: 81 CELTKLQVD--GTLPVLGTLDLSHNQLQSLPLLGQTLPALTVLDVSFNRLTSLPLGALRG 138
Query: 554 LKKLEVLNISNNFVQTLPV-CLKNLNNLKQVYASNNKLQAFPKQIL-GLQSLDVLDLSHN 381
L +L+ L + N ++TLP L L+++ +NN L P +L GL++LD L L N
Sbjct: 139 LGELQELYLKGNELKTLPPGLLTPTPKLEKLSLANNNLTELPAGLLNGLENLDTLLLQEN 198
Query: 380 KITEIPYG 357
+ IP G
Sbjct: 199 SLYTIPKG 206
Score = 52.8 bits (121), Expect = 1e-06
Identities = 41/119 (34%), Positives = 59/119 (49%), Gaps = 3/119 (2%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLP-DDLSKLKHLKQLNLDSNKLQALPESLIN- 555
+L+ +P+ + L LD+S N+L+ LP L L L++L L N+L+ LP L+
Sbjct: 104 QLQSLPL-LGQTLPALTVLDVSFNRLTSLPLGALRGLGELQELYLKGNELKTLPPGLLTP 162
Query: 554 LKKLEVLNISNNFVQTLPVCLKN-LNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHN 381
KLE L+++NN + LP L N L NL + N L PK G L L N
Sbjct: 163 TPKLEKLSLANNNLTELPAGLLNGLENLDTLLLQENSLYTIPKGFFGSHLLPFAFLHGN 221
Score = 46.8 bits (106), Expect = 8e-05
Identities = 54/179 (30%), Positives = 84/179 (46%), Gaps = 11/179 (6%)
Frame = -2
Query: 713 PIDVFSLCDVLR-----NLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALP-ESLINL 552
P+ +C+V + ++ K L+ LP DL K + L+L N L +L+
Sbjct: 13 PLHPHPICEVSKVASHLEVNCDKRNLTALPPDLPKDTTI--LHLSENLLYTFSLATLMPY 70
Query: 551 KKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKIT 372
+L LN+ + L V L L + S+N+LQ+ P L +L VLD+S N++T
Sbjct: 71 TRLTQLNLDRCELTKLQVD-GTLPVLGTLDLSHNQLQSLPLLGQTLPALTVLDVSFNRLT 129
Query: 371 EIPY----GMSELYVIELNLSQNEISLIGED-LHQAPRLKILRLDENCLSLDEIKPSLL 210
+P G+ EL EL L NE+ + L P+L+ L L N +L E+ LL
Sbjct: 130 SLPLGALRGLGELQ--ELYLKGNELKTLPPGLLTPTPKLEKLSLANN--NLTELPAGLL 184
>BC047905-1|AAH47905.2| 915|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 6 protein.
Length = 915
Score = 59.3 bits (137), Expect = 1e-08
Identities = 50/161 (31%), Positives = 77/161 (47%), Gaps = 6/161 (3%)
Frame = -2
Query: 716 IPIDVFSLCDVLRNLDLSKNKLSVLP-DDLSKLKHLKQLNLDSNKLQALPE-SLINLKKL 543
+P F LR+L L N L+ +P L+ L L+ + L N++ +P+ + NL L
Sbjct: 101 VPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTSL 160
Query: 542 EVLNISNNFVQTLPV-CLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEI 366
VL++ NN +Q L + L+NL+ + + NKLQ FP I L L L +N I I
Sbjct: 161 VVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQEFPVAIRTLGRLQELGFHNNNIKAI 220
Query: 365 PYG--MSELYVIELNLSQNEISLIGEDLHQ-APRLKILRLD 252
P M + ++ N I +G Q P+L L L+
Sbjct: 221 PEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLSLN 261
Score = 58.8 bits (136), Expect = 2e-08
Identities = 51/166 (30%), Positives = 82/166 (49%), Gaps = 6/166 (3%)
Frame = -2
Query: 734 DCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPD-DLSKLKHLKQLNLDSNKLQAL-PESL 561
D L EIP+ + L+ + L+ N++S +PD L L L+L +N++Q L S
Sbjct: 119 DNALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSF 178
Query: 560 INLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFP-KQILGLQSLDVLDLSH 384
L LE L+++ N +Q PV ++ L L+++ NN ++A P K +G L +
Sbjct: 179 EGLHNLETLDLNYNKLQEFPVAIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYD 238
Query: 383 NKITEIPYGMSELYVIELN-LSQNEISLIGE--DLHQAPRLKILRL 255
N I + + Y+ +L+ LS N I E DL L+IL L
Sbjct: 239 NPIQFVGRSAFQ-YLPKLHTLSLNGAMDIQEFPDLKGTTSLEILTL 283
Score = 53.6 bits (123), Expect = 7e-07
Identities = 57/214 (26%), Positives = 96/214 (44%), Gaps = 30/214 (14%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDD-LSKLKHLKQLNLDSNKLQALPE------ 567
L IP FS L+ L L N+L +P + L +L L+ L LD+N + +PE
Sbjct: 50 LSHIPGQAFSGLYSLKILMLQNNQLGGIPAEALWELPSLQSLRLDANLISLVPERSFEGL 109
Query: 566 -------------------SLINLKKLEVLNISNNFVQTLP-VCLKNLNNLKQVYASNNK 447
+L NL L+ + ++ N + +P +NL +L ++ NN+
Sbjct: 110 SSLRHLWLDDNALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNR 169
Query: 446 LQAF-PKQILGLQSLDVLDLSHNKITEIPYGMSEL-YVIELNLSQNEISLIGEDLHQA-P 276
+Q GL +L+ LDL++NK+ E P + L + EL N I I E P
Sbjct: 170 IQHLGTHSFEGLHNLETLDLNYNKLQEFPVAIRTLGRLQELGFHNNNIKAIPEKAFMGNP 229
Query: 275 RLKILRLDENCLSLDEIKPSLLRDSKIHTVSVDG 174
L+ + +N + + + K+HT+S++G
Sbjct: 230 LLQTIHFYDNPIQFVG-RSAFQYLPKLHTLSLNG 262
Score = 49.2 bits (112), Expect = 2e-05
Identities = 42/151 (27%), Positives = 75/151 (49%), Gaps = 5/151 (3%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPE-SLINLKKLEVLNISNNFVQT 507
L LDL+ NKL P + L L++L +N ++A+PE + + L+ ++ +N +Q
Sbjct: 184 LETLDLNYNKLQEFPVAIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPIQF 243
Query: 506 L-PVCLKNLNNLKQVYASN-NKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELY--V 339
+ + L L + + +Q FP + G SL++L L+ I +P GM + +
Sbjct: 244 VGRSAFQYLPKLHTLSLNGAMDIQEFP-DLKGTTSLEILTLTRAGIRLLPSGMCQQLPRL 302
Query: 338 IELNLSQNEISLIGEDLHQAPRLKILRLDEN 246
L LS N+I + LH+ +L+ + L N
Sbjct: 303 RVLELSHNQIEEL-PSLHRCQKLEEIGLQHN 332
Score = 43.2 bits (97), Expect = 0.001
Identities = 47/174 (27%), Positives = 79/174 (45%), Gaps = 7/174 (4%)
Frame = -2
Query: 692 CDVLRNLDLSKNKL-SVLPDDLSKLKHLKQLNLDSNKLQAL-PESLINLKKLEVLNISNN 519
C L + L N++ + D S+L L+ L+L N ++++ PE+ L L L++++N
Sbjct: 321 CQKLEEIGLQHNRIWEIGADTFSQLSSLQALDLSWNAIRSIHPEAFSTLHSLVKLDLTDN 380
Query: 518 FVQTLPVCLKNLNNLKQVYASNNKL--QAFPKQILGLQSLDVLDLSHNKITEIPYGM-SE 348
+ TLP L L L + N QAF K L +L++ + PYGM +
Sbjct: 381 QLTTLP--LAGLGGLMHLKLKGNLALSQAFSKD--SFPKLRILEVPY-AYQCCPYGMCAS 435
Query: 347 LYVIELNLSQNEISLIGEDLHQAPRLKILRLDENCL--SLDEIKPSLLRDSKIH 192
+ ++ L E+ + P + R EN LDE++ + DSK H
Sbjct: 436 FFKASGQWEAEDLHLDDEESSKRPLGLLARQAENHYDQDLDELQLE-MEDSKPH 488
Score = 36.7 bits (81), Expect = 0.087
Identities = 27/71 (38%), Positives = 37/71 (52%), Gaps = 1/71 (1%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKL-SVLPDDLSKLKHLKQLNLDSNKLQALPESLINL 552
++ EI D FS L+ LDLS N + S+ P+ S L L +L+L N+L LP L L
Sbjct: 333 RIWEIGADTFSQLSSLQALDLSWNAIRSIHPEAFSTLHSLVKLDLTDNQLTTLP--LAGL 390
Query: 551 KKLEVLNISNN 519
L L + N
Sbjct: 391 GGLMHLKLKGN 401
>BC027955-1|AAH27955.1| 626|Homo sapiens glycoprotein Ib
(platelet), alpha polypeptide protein.
Length = 626
Score = 59.3 bits (137), Expect = 1e-08
Identities = 45/128 (35%), Positives = 68/128 (53%), Gaps = 3/128 (2%)
Frame = -2
Query: 731 CKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALP-ESLIN 555
C+L ++ +D VL LDLS N+L LP L L L++ N+L +LP +L
Sbjct: 81 CELTKLQVD--GTLPVLGTLDLSHNQLQSLPLLGQTLPALTVLDVSFNRLTSLPLGALRG 138
Query: 554 LKKLEVLNISNNFVQTLPV-CLKNLNNLKQVYASNNKLQAFPKQIL-GLQSLDVLDLSHN 381
L +L+ L + N ++TLP L L+++ +NN L P +L GL++LD L L N
Sbjct: 139 LGELQELYLKGNELKTLPPGLLTPTPKLEKLSLANNNLTELPAGLLNGLENLDTLLLQEN 198
Query: 380 KITEIPYG 357
+ IP G
Sbjct: 199 SLYTIPKG 206
Score = 52.8 bits (121), Expect = 1e-06
Identities = 41/119 (34%), Positives = 59/119 (49%), Gaps = 3/119 (2%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLP-DDLSKLKHLKQLNLDSNKLQALPESLIN- 555
+L+ +P+ + L LD+S N+L+ LP L L L++L L N+L+ LP L+
Sbjct: 104 QLQSLPL-LGQTLPALTVLDVSFNRLTSLPLGALRGLGELQELYLKGNELKTLPPGLLTP 162
Query: 554 LKKLEVLNISNNFVQTLPVCLKN-LNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHN 381
KLE L+++NN + LP L N L NL + N L PK G L L N
Sbjct: 163 TPKLEKLSLANNNLTELPAGLLNGLENLDTLLLQENSLYTIPKGFFGSHLLPFAFLHGN 221
Score = 46.8 bits (106), Expect = 8e-05
Identities = 54/179 (30%), Positives = 84/179 (46%), Gaps = 11/179 (6%)
Frame = -2
Query: 713 PIDVFSLCDVLR-----NLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALP-ESLINL 552
P+ +C+V + ++ K L+ LP DL K + L+L N L +L+
Sbjct: 13 PLHPHPICEVSKVASHLEVNCDKRNLTALPPDLPKDTTI--LHLSENLLYTFSLATLMPY 70
Query: 551 KKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKIT 372
+L LN+ + L V L L + S+N+LQ+ P L +L VLD+S N++T
Sbjct: 71 TRLTQLNLDRCELTKLQVD-GTLPVLGTLDLSHNQLQSLPLLGQTLPALTVLDVSFNRLT 129
Query: 371 EIPY----GMSELYVIELNLSQNEISLIGED-LHQAPRLKILRLDENCLSLDEIKPSLL 210
+P G+ EL EL L NE+ + L P+L+ L L N +L E+ LL
Sbjct: 130 SLPLGALRGLGELQ--ELYLKGNELKTLPPGLLTPTPKLEKLSLANN--NLTELPAGLL 184
>AY730707-1|AAU44786.1| 1093|Homo sapiens leucine-rich repeat
protein LRIG1 protein.
Length = 1093
Score = 59.3 bits (137), Expect = 1e-08
Identities = 53/158 (33%), Positives = 79/158 (50%), Gaps = 7/158 (4%)
Frame = -2
Query: 677 NLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQAL-PESLINLKKLEVLNISNNFVQTL- 504
+LD L+ LP DL + LNL NKL + P +L L+ +N+S N + +
Sbjct: 51 SLDCGGRGLAALPGDLPSWT--RSLNLSYNKLSEIDPAGFEDLPNLQEVNLSYNKLSEID 108
Query: 503 PVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDV--LDLSHNKITEIPYGMSELYV-IE 333
P ++L NL++VY +NN+L A P LG S V L L HNKI + + Y+ +E
Sbjct: 109 PAGFEDLPNLQEVYLNNNELTAVPS--LGAASSHVVSLFLQHNKIRSVEGSQLKAYLSLE 166
Query: 332 -LNLSQNEISLIGED-LHQAPRLKILRLDENCLSLDEI 225
L+LS N I+ + P +K L L N + E+
Sbjct: 167 VLDLSLNNITEVRNTCFPHGPPIKELNLAGNRIGTLEL 204
Score = 36.3 bits (80), Expect = 0.12
Identities = 34/105 (32%), Positives = 51/105 (48%), Gaps = 4/105 (3%)
Frame = -2
Query: 674 LDLSKNKL-SVLPDDLSKLKHLKQLNLDSNKLQALPESLINL-KKLEVLNIS-NNFVQTL 504
L L N L V L L L QL+L +N + + + +KL L +S NN +
Sbjct: 288 LHLEYNSLVEVNSGSLYGLTALHQLHLSNNSIARIHRKGWSFCQKLHELVLSFNNLTRLD 347
Query: 503 PVCLKNLNNLKQVYASNNKLQAFPKQIL-GLQSLDVLDLSHNKIT 372
L L++L + S+N + + GL+SL VLDL HN+I+
Sbjct: 348 EESLAELSSLSVLRLSHNSISHIAEGAFKGLRSLRVLDLDHNEIS 392
Score = 35.5 bits (78), Expect = 0.20
Identities = 55/218 (25%), Positives = 94/218 (43%), Gaps = 32/218 (14%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
KL EI F L+ + L+ N+L+ +P + H+ L L NK++++ S +
Sbjct: 103 KLSEIDPAGFEDLPNLQEVYLNNNELTAVPSLGAASSHVVSLFLQHNKIRSVEGSQLKAY 162
Query: 548 -KLEVLNIS-NNFVQTLPVC------LKNLN-------------------NLKQVYASNN 450
LEVL++S NN + C +K LN +L + S N
Sbjct: 163 LSLEVLDLSLNNITEVRNTCFPHGPPIKELNLAGNRIGTLELGAFDGLSRSLLTLRLSKN 222
Query: 449 KLQAFPKQILGLQSLDVLDLSHNKITEIP----YGMSELYVIELNLSQNEISLIGEDLHQ 282
++ P + L L LDL+ N+I I G++ L V L L +N IS + +
Sbjct: 223 RITQLPVRAFKLPRLTQLDLNRNRIRLIEGLTFQGLNSLEV--LKLQRNNISKLTDGAFW 280
Query: 281 A-PRLKILRLDENCLSLDEIKPSLLRDSKIHTVSVDGN 171
++ +L L+ N L ++ SL + +H + + N
Sbjct: 281 GLSKMHVLHLEYNSL-VEVNSGSLYGLTALHQLHLSNN 317
>AY358119-1|AAQ88486.1| 915|Homo sapiens gonadotropin receptor
protein.
Length = 915
Score = 59.3 bits (137), Expect = 1e-08
Identities = 50/161 (31%), Positives = 77/161 (47%), Gaps = 6/161 (3%)
Frame = -2
Query: 716 IPIDVFSLCDVLRNLDLSKNKLSVLP-DDLSKLKHLKQLNLDSNKLQALPE-SLINLKKL 543
+P F LR+L L N L+ +P L+ L L+ + L N++ +P+ + NL L
Sbjct: 101 VPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTSL 160
Query: 542 EVLNISNNFVQTLPV-CLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEI 366
VL++ NN +Q L + L+NL+ + + NKLQ FP I L L L +N I I
Sbjct: 161 VVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQEFPVAIRTLGRLQELGFHNNNIKAI 220
Query: 365 PYG--MSELYVIELNLSQNEISLIGEDLHQ-APRLKILRLD 252
P M + ++ N I +G Q P+L L L+
Sbjct: 221 PEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLSLN 261
Score = 58.8 bits (136), Expect = 2e-08
Identities = 51/166 (30%), Positives = 82/166 (49%), Gaps = 6/166 (3%)
Frame = -2
Query: 734 DCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPD-DLSKLKHLKQLNLDSNKLQAL-PESL 561
D L EIP+ + L+ + L+ N++S +PD L L L+L +N++Q L S
Sbjct: 119 DNALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSF 178
Query: 560 INLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFP-KQILGLQSLDVLDLSH 384
L LE L+++ N +Q PV ++ L L+++ NN ++A P K +G L +
Sbjct: 179 EGLHNLETLDLNYNKLQEFPVAIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYD 238
Query: 383 NKITEIPYGMSELYVIELN-LSQNEISLIGE--DLHQAPRLKILRL 255
N I + + Y+ +L+ LS N I E DL L+IL L
Sbjct: 239 NPIQFVGRSAFQ-YLPKLHTLSLNGAMDIQEFPDLKGTTSLEILTL 283
Score = 53.6 bits (123), Expect = 7e-07
Identities = 57/214 (26%), Positives = 96/214 (44%), Gaps = 30/214 (14%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDD-LSKLKHLKQLNLDSNKLQALPE------ 567
L IP FS L+ L L N+L +P + L +L L+ L LD+N + +PE
Sbjct: 50 LSHIPGQAFSGLYSLKILMLQNNQLGGIPAEALWELPSLQSLRLDANLISLVPERSFEGL 109
Query: 566 -------------------SLINLKKLEVLNISNNFVQTLP-VCLKNLNNLKQVYASNNK 447
+L NL L+ + ++ N + +P +NL +L ++ NN+
Sbjct: 110 SSLRHLWLDDNALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNR 169
Query: 446 LQAF-PKQILGLQSLDVLDLSHNKITEIPYGMSEL-YVIELNLSQNEISLIGEDLHQA-P 276
+Q GL +L+ LDL++NK+ E P + L + EL N I I E P
Sbjct: 170 IQHLGTHSFEGLHNLETLDLNYNKLQEFPVAIRTLGRLQELGFHNNNIKAIPEKAFMGNP 229
Query: 275 RLKILRLDENCLSLDEIKPSLLRDSKIHTVSVDG 174
L+ + +N + + + K+HT+S++G
Sbjct: 230 LLQTIHFYDNPIQFVG-RSAFQYLPKLHTLSLNG 262
Score = 49.2 bits (112), Expect = 2e-05
Identities = 42/151 (27%), Positives = 75/151 (49%), Gaps = 5/151 (3%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPE-SLINLKKLEVLNISNNFVQT 507
L LDL+ NKL P + L L++L +N ++A+PE + + L+ ++ +N +Q
Sbjct: 184 LETLDLNYNKLQEFPVAIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPIQF 243
Query: 506 L-PVCLKNLNNLKQVYASN-NKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELY--V 339
+ + L L + + +Q FP + G SL++L L+ I +P GM + +
Sbjct: 244 VGRSAFQYLPKLHTLSLNGAMDIQEFP-DLKGTTSLEILTLTRAGIRLLPSGMCQQLPRL 302
Query: 338 IELNLSQNEISLIGEDLHQAPRLKILRLDEN 246
L LS N+I + LH+ +L+ + L N
Sbjct: 303 RVLELSHNQIEEL-PSLHRCQKLEEIGLQHN 332
Score = 43.2 bits (97), Expect = 0.001
Identities = 47/174 (27%), Positives = 79/174 (45%), Gaps = 7/174 (4%)
Frame = -2
Query: 692 CDVLRNLDLSKNKL-SVLPDDLSKLKHLKQLNLDSNKLQAL-PESLINLKKLEVLNISNN 519
C L + L N++ + D S+L L+ L+L N ++++ PE+ L L L++++N
Sbjct: 321 CQKLEEIGLQHNRIWEIGADTFSQLSSLQALDLSWNAIRSIHPEAFSTLHSLVKLDLTDN 380
Query: 518 FVQTLPVCLKNLNNLKQVYASNNKL--QAFPKQILGLQSLDVLDLSHNKITEIPYGM-SE 348
+ TLP L L L + N QAF K L +L++ + PYGM +
Sbjct: 381 QLTTLP--LAGLGGLMHLKLKGNLALSQAFSKD--SFPKLRILEVPY-AYQCCPYGMCAS 435
Query: 347 LYVIELNLSQNEISLIGEDLHQAPRLKILRLDENCL--SLDEIKPSLLRDSKIH 192
+ ++ L E+ + P + R EN LDE++ + DSK H
Sbjct: 436 FFKASGQWEAEDLHLDDEESSKRPLGLLARQAENHYDQDLDELQLE-MEDSKPH 488
Score = 36.7 bits (81), Expect = 0.087
Identities = 27/71 (38%), Positives = 37/71 (52%), Gaps = 1/71 (1%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKL-SVLPDDLSKLKHLKQLNLDSNKLQALPESLINL 552
++ EI D FS L+ LDLS N + S+ P+ S L L +L+L N+L LP L L
Sbjct: 333 RIWEIGADTFSQLSSLQALDLSWNAIRSIHPEAFSTLHSLVKLDLTDNQLTTLP--LAGL 390
Query: 551 KKLEVLNISNN 519
L L + N
Sbjct: 391 GGLMHLKLKGN 401
>AM709890-1|CAM97225.1| 639|Homo sapiens platelet glycoprotein Ib
alpha polypeptide protein.
Length = 639
Score = 59.3 bits (137), Expect = 1e-08
Identities = 45/128 (35%), Positives = 68/128 (53%), Gaps = 3/128 (2%)
Frame = -2
Query: 731 CKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALP-ESLIN 555
C+L ++ +D VL LDLS N+L LP L L L++ N+L +LP +L
Sbjct: 81 CELTKLQVD--GTLPVLGTLDLSHNQLQSLPLLGQTLPALTVLDVSFNRLTSLPLGALRG 138
Query: 554 LKKLEVLNISNNFVQTLPV-CLKNLNNLKQVYASNNKLQAFPKQIL-GLQSLDVLDLSHN 381
L +L+ L + N ++TLP L L+++ +NN L P +L GL++LD L L N
Sbjct: 139 LGELQELYLKGNELKTLPPGLLTPTPKLEKLSLANNNLTELPAGLLNGLENLDTLLLQEN 198
Query: 380 KITEIPYG 357
+ IP G
Sbjct: 199 SLYTIPKG 206
Score = 52.8 bits (121), Expect = 1e-06
Identities = 41/119 (34%), Positives = 59/119 (49%), Gaps = 3/119 (2%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLP-DDLSKLKHLKQLNLDSNKLQALPESLIN- 555
+L+ +P+ + L LD+S N+L+ LP L L L++L L N+L+ LP L+
Sbjct: 104 QLQSLPL-LGQTLPALTVLDVSFNRLTSLPLGALRGLGELQELYLKGNELKTLPPGLLTP 162
Query: 554 LKKLEVLNISNNFVQTLPVCLKN-LNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHN 381
KLE L+++NN + LP L N L NL + N L PK G L L N
Sbjct: 163 TPKLEKLSLANNNLTELPAGLLNGLENLDTLLLQENSLYTIPKGFFGSHLLPFAFLHGN 221
Score = 46.8 bits (106), Expect = 8e-05
Identities = 54/179 (30%), Positives = 84/179 (46%), Gaps = 11/179 (6%)
Frame = -2
Query: 713 PIDVFSLCDVLR-----NLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALP-ESLINL 552
P+ +C+V + ++ K L+ LP DL K + L+L N L +L+
Sbjct: 13 PLHPHPICEVSKVASHLEVNCDKRNLTALPPDLPKDTTI--LHLSENLLYTFSLATLMPY 70
Query: 551 KKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKIT 372
+L LN+ + L V L L + S+N+LQ+ P L +L VLD+S N++T
Sbjct: 71 TRLTQLNLDRCELTKLQVD-GTLPVLGTLDLSHNQLQSLPLLGQTLPALTVLDVSFNRLT 129
Query: 371 EIPY----GMSELYVIELNLSQNEISLIGED-LHQAPRLKILRLDENCLSLDEIKPSLL 210
+P G+ EL EL L NE+ + L P+L+ L L N +L E+ LL
Sbjct: 130 SLPLGALRGLGELQ--ELYLKGNELKTLPPGLLTPTPKLEKLSLANN--NLTELPAGLL 184
>AL356953-3|CAI15929.1| 915|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 6 protein.
Length = 915
Score = 59.3 bits (137), Expect = 1e-08
Identities = 50/161 (31%), Positives = 77/161 (47%), Gaps = 6/161 (3%)
Frame = -2
Query: 716 IPIDVFSLCDVLRNLDLSKNKLSVLP-DDLSKLKHLKQLNLDSNKLQALPE-SLINLKKL 543
+P F LR+L L N L+ +P L+ L L+ + L N++ +P+ + NL L
Sbjct: 101 VPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTSL 160
Query: 542 EVLNISNNFVQTLPV-CLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEI 366
VL++ NN +Q L + L+NL+ + + NKLQ FP I L L L +N I I
Sbjct: 161 VVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQEFPVAIRTLGRLQELGFHNNNIKAI 220
Query: 365 PYG--MSELYVIELNLSQNEISLIGEDLHQ-APRLKILRLD 252
P M + ++ N I +G Q P+L L L+
Sbjct: 221 PEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLSLN 261
Score = 58.8 bits (136), Expect = 2e-08
Identities = 51/166 (30%), Positives = 82/166 (49%), Gaps = 6/166 (3%)
Frame = -2
Query: 734 DCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPD-DLSKLKHLKQLNLDSNKLQAL-PESL 561
D L EIP+ + L+ + L+ N++S +PD L L L+L +N++Q L S
Sbjct: 119 DNALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSF 178
Query: 560 INLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFP-KQILGLQSLDVLDLSH 384
L LE L+++ N +Q PV ++ L L+++ NN ++A P K +G L +
Sbjct: 179 EGLHNLETLDLNYNKLQEFPVAIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYD 238
Query: 383 NKITEIPYGMSELYVIELN-LSQNEISLIGE--DLHQAPRLKILRL 255
N I + + Y+ +L+ LS N I E DL L+IL L
Sbjct: 239 NPIQFVGRSAFQ-YLPKLHTLSLNGAMDIQEFPDLKGTTSLEILTL 283
Score = 53.6 bits (123), Expect = 7e-07
Identities = 57/214 (26%), Positives = 96/214 (44%), Gaps = 30/214 (14%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDD-LSKLKHLKQLNLDSNKLQALPE------ 567
L IP FS L+ L L N+L +P + L +L L+ L LD+N + +PE
Sbjct: 50 LSHIPGQAFSGLYSLKILMLQNNQLGGIPAEALWELPSLQSLRLDANLISLVPERSFEGL 109
Query: 566 -------------------SLINLKKLEVLNISNNFVQTLP-VCLKNLNNLKQVYASNNK 447
+L NL L+ + ++ N + +P +NL +L ++ NN+
Sbjct: 110 SSLRHLWLDDNALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNR 169
Query: 446 LQAF-PKQILGLQSLDVLDLSHNKITEIPYGMSEL-YVIELNLSQNEISLIGEDLHQA-P 276
+Q GL +L+ LDL++NK+ E P + L + EL N I I E P
Sbjct: 170 IQHLGTHSFEGLHNLETLDLNYNKLQEFPVAIRTLGRLQELGFHNNNIKAIPEKAFMGNP 229
Query: 275 RLKILRLDENCLSLDEIKPSLLRDSKIHTVSVDG 174
L+ + +N + + + K+HT+S++G
Sbjct: 230 LLQTIHFYDNPIQFVG-RSAFQYLPKLHTLSLNG 262
Score = 49.2 bits (112), Expect = 2e-05
Identities = 42/151 (27%), Positives = 75/151 (49%), Gaps = 5/151 (3%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPE-SLINLKKLEVLNISNNFVQT 507
L LDL+ NKL P + L L++L +N ++A+PE + + L+ ++ +N +Q
Sbjct: 184 LETLDLNYNKLQEFPVAIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPIQF 243
Query: 506 L-PVCLKNLNNLKQVYASN-NKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELY--V 339
+ + L L + + +Q FP + G SL++L L+ I +P GM + +
Sbjct: 244 VGRSAFQYLPKLHTLSLNGAMDIQEFP-DLKGTTSLEILTLTRAGIRLLPSGMCQQLPRL 302
Query: 338 IELNLSQNEISLIGEDLHQAPRLKILRLDEN 246
L LS N+I + LH+ +L+ + L N
Sbjct: 303 RVLELSHNQIEEL-PSLHRCQKLEEIGLQHN 332
Score = 43.2 bits (97), Expect = 0.001
Identities = 47/174 (27%), Positives = 79/174 (45%), Gaps = 7/174 (4%)
Frame = -2
Query: 692 CDVLRNLDLSKNKL-SVLPDDLSKLKHLKQLNLDSNKLQAL-PESLINLKKLEVLNISNN 519
C L + L N++ + D S+L L+ L+L N ++++ PE+ L L L++++N
Sbjct: 321 CQKLEEIGLQHNRIWEIGADTFSQLSSLQALDLSWNAIRSIHPEAFSTLHSLVKLDLTDN 380
Query: 518 FVQTLPVCLKNLNNLKQVYASNNKL--QAFPKQILGLQSLDVLDLSHNKITEIPYGM-SE 348
+ TLP L L L + N QAF K L +L++ + PYGM +
Sbjct: 381 QLTTLP--LAGLGGLMHLKLKGNLALSQAFSKD--SFPKLRILEVPY-AYQCCPYGMCAS 435
Query: 347 LYVIELNLSQNEISLIGEDLHQAPRLKILRLDENCL--SLDEIKPSLLRDSKIH 192
+ ++ L E+ + P + R EN LDE++ + DSK H
Sbjct: 436 FFKASGQWEAEDLHLDDEESSKRPLGLLARQAENHYDQDLDELQLE-MEDSKPH 488
Score = 36.7 bits (81), Expect = 0.087
Identities = 27/71 (38%), Positives = 37/71 (52%), Gaps = 1/71 (1%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKL-SVLPDDLSKLKHLKQLNLDSNKLQALPESLINL 552
++ EI D FS L+ LDLS N + S+ P+ S L L +L+L N+L LP L L
Sbjct: 333 RIWEIGADTFSQLSSLQALDLSWNAIRSIHPEAFSTLHSLVKLDLTDNQLTTLP--LAGL 390
Query: 551 KKLEVLNISNN 519
L L + N
Sbjct: 391 GGLMHLKLKGN 401
>AL356953-1|CAI15927.1| 967|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 6 protein.
Length = 967
Score = 59.3 bits (137), Expect = 1e-08
Identities = 50/161 (31%), Positives = 77/161 (47%), Gaps = 6/161 (3%)
Frame = -2
Query: 716 IPIDVFSLCDVLRNLDLSKNKLSVLP-DDLSKLKHLKQLNLDSNKLQALPE-SLINLKKL 543
+P F LR+L L N L+ +P L+ L L+ + L N++ +P+ + NL L
Sbjct: 153 VPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTSL 212
Query: 542 EVLNISNNFVQTLPV-CLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEI 366
VL++ NN +Q L + L+NL+ + + NKLQ FP I L L L +N I I
Sbjct: 213 VVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQEFPVAIRTLGRLQELGFHNNNIKAI 272
Query: 365 PYG--MSELYVIELNLSQNEISLIGEDLHQ-APRLKILRLD 252
P M + ++ N I +G Q P+L L L+
Sbjct: 273 PEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLSLN 313
Score = 58.8 bits (136), Expect = 2e-08
Identities = 51/166 (30%), Positives = 82/166 (49%), Gaps = 6/166 (3%)
Frame = -2
Query: 734 DCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPD-DLSKLKHLKQLNLDSNKLQAL-PESL 561
D L EIP+ + L+ + L+ N++S +PD L L L+L +N++Q L S
Sbjct: 171 DNALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSF 230
Query: 560 INLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFP-KQILGLQSLDVLDLSH 384
L LE L+++ N +Q PV ++ L L+++ NN ++A P K +G L +
Sbjct: 231 EGLHNLETLDLNYNKLQEFPVAIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYD 290
Query: 383 NKITEIPYGMSELYVIELN-LSQNEISLIGE--DLHQAPRLKILRL 255
N I + + Y+ +L+ LS N I E DL L+IL L
Sbjct: 291 NPIQFVGRSAFQ-YLPKLHTLSLNGAMDIQEFPDLKGTTSLEILTL 335
Score = 53.6 bits (123), Expect = 7e-07
Identities = 57/214 (26%), Positives = 96/214 (44%), Gaps = 30/214 (14%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDD-LSKLKHLKQLNLDSNKLQALPE------ 567
L IP FS L+ L L N+L +P + L +L L+ L LD+N + +PE
Sbjct: 102 LSHIPGQAFSGLYSLKILMLQNNQLGGIPAEALWELPSLQSLRLDANLISLVPERSFEGL 161
Query: 566 -------------------SLINLKKLEVLNISNNFVQTLP-VCLKNLNNLKQVYASNNK 447
+L NL L+ + ++ N + +P +NL +L ++ NN+
Sbjct: 162 SSLRHLWLDDNALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNR 221
Query: 446 LQAF-PKQILGLQSLDVLDLSHNKITEIPYGMSEL-YVIELNLSQNEISLIGEDLHQA-P 276
+Q GL +L+ LDL++NK+ E P + L + EL N I I E P
Sbjct: 222 IQHLGTHSFEGLHNLETLDLNYNKLQEFPVAIRTLGRLQELGFHNNNIKAIPEKAFMGNP 281
Query: 275 RLKILRLDENCLSLDEIKPSLLRDSKIHTVSVDG 174
L+ + +N + + + K+HT+S++G
Sbjct: 282 LLQTIHFYDNPIQFVG-RSAFQYLPKLHTLSLNG 314
Score = 49.2 bits (112), Expect = 2e-05
Identities = 42/151 (27%), Positives = 75/151 (49%), Gaps = 5/151 (3%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPE-SLINLKKLEVLNISNNFVQT 507
L LDL+ NKL P + L L++L +N ++A+PE + + L+ ++ +N +Q
Sbjct: 236 LETLDLNYNKLQEFPVAIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPIQF 295
Query: 506 L-PVCLKNLNNLKQVYASN-NKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELY--V 339
+ + L L + + +Q FP + G SL++L L+ I +P GM + +
Sbjct: 296 VGRSAFQYLPKLHTLSLNGAMDIQEFP-DLKGTTSLEILTLTRAGIRLLPSGMCQQLPRL 354
Query: 338 IELNLSQNEISLIGEDLHQAPRLKILRLDEN 246
L LS N+I + LH+ +L+ + L N
Sbjct: 355 RVLELSHNQIEEL-PSLHRCQKLEEIGLQHN 384
Score = 43.2 bits (97), Expect = 0.001
Identities = 47/174 (27%), Positives = 79/174 (45%), Gaps = 7/174 (4%)
Frame = -2
Query: 692 CDVLRNLDLSKNKL-SVLPDDLSKLKHLKQLNLDSNKLQAL-PESLINLKKLEVLNISNN 519
C L + L N++ + D S+L L+ L+L N ++++ PE+ L L L++++N
Sbjct: 373 CQKLEEIGLQHNRIWEIGADTFSQLSSLQALDLSWNAIRSIHPEAFSTLHSLVKLDLTDN 432
Query: 518 FVQTLPVCLKNLNNLKQVYASNNKL--QAFPKQILGLQSLDVLDLSHNKITEIPYGM-SE 348
+ TLP L L L + N QAF K L +L++ + PYGM +
Sbjct: 433 QLTTLP--LAGLGGLMHLKLKGNLALSQAFSKD--SFPKLRILEVPY-AYQCCPYGMCAS 487
Query: 347 LYVIELNLSQNEISLIGEDLHQAPRLKILRLDENCL--SLDEIKPSLLRDSKIH 192
+ ++ L E+ + P + R EN LDE++ + DSK H
Sbjct: 488 FFKASGQWEAEDLHLDDEESSKRPLGLLARQAENHYDQDLDELQLE-MEDSKPH 540
Score = 36.7 bits (81), Expect = 0.087
Identities = 27/71 (38%), Positives = 37/71 (52%), Gaps = 1/71 (1%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKL-SVLPDDLSKLKHLKQLNLDSNKLQALPESLINL 552
++ EI D FS L+ LDLS N + S+ P+ S L L +L+L N+L LP L L
Sbjct: 385 RIWEIGADTFSQLSSLQALDLSWNAIRSIHPEAFSTLHSLVKLDLTDNQLTTLP--LAGL 442
Query: 551 KKLEVLNISNN 519
L L + N
Sbjct: 443 GGLMHLKLKGN 453
>AF395009-1|AAK71325.1| 626|Homo sapiens glycoprotein Ib
(platelet), alpha polypeptide protein.
Length = 626
Score = 59.3 bits (137), Expect = 1e-08
Identities = 45/128 (35%), Positives = 68/128 (53%), Gaps = 3/128 (2%)
Frame = -2
Query: 731 CKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALP-ESLIN 555
C+L ++ +D VL LDLS N+L LP L L L++ N+L +LP +L
Sbjct: 81 CELTKLQVD--GTLPVLGTLDLSHNQLQSLPLLGQTLPALTVLDVSFNRLTSLPLGALRG 138
Query: 554 LKKLEVLNISNNFVQTLPV-CLKNLNNLKQVYASNNKLQAFPKQIL-GLQSLDVLDLSHN 381
L +L+ L + N ++TLP L L+++ +NN L P +L GL++LD L L N
Sbjct: 139 LGELQELYLKGNELKTLPPGLLTPTPKLEKLSLANNNLTELPAGLLNGLENLDTLLLQEN 198
Query: 380 KITEIPYG 357
+ IP G
Sbjct: 199 SLYTIPKG 206
Score = 52.8 bits (121), Expect = 1e-06
Identities = 41/119 (34%), Positives = 59/119 (49%), Gaps = 3/119 (2%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLP-DDLSKLKHLKQLNLDSNKLQALPESLIN- 555
+L+ +P+ + L LD+S N+L+ LP L L L++L L N+L+ LP L+
Sbjct: 104 QLQSLPL-LGQTLPALTVLDVSFNRLTSLPLGALRGLGELQELYLKGNELKTLPPGLLTP 162
Query: 554 LKKLEVLNISNNFVQTLPVCLKN-LNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHN 381
KLE L+++NN + LP L N L NL + N L PK G L L N
Sbjct: 163 TPKLEKLSLANNNLTELPAGLLNGLENLDTLLLQENSLYTIPKGFFGSHLLPFAFLHGN 221
Score = 46.8 bits (106), Expect = 8e-05
Identities = 54/179 (30%), Positives = 84/179 (46%), Gaps = 11/179 (6%)
Frame = -2
Query: 713 PIDVFSLCDVLR-----NLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALP-ESLINL 552
P+ +C+V + ++ K L+ LP DL K + L+L N L +L+
Sbjct: 13 PLHPHPICEVSKVASHLEVNCDKRNLTALPPDLPKDTTI--LHLSENLLYTFSLATLMPY 70
Query: 551 KKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKIT 372
+L LN+ + L V L L + S+N+LQ+ P L +L VLD+S N++T
Sbjct: 71 TRLTQLNLDRCELTKLQVD-GTLPVLGTLDLSHNQLQSLPLLGQTLPALTVLDVSFNRLT 129
Query: 371 EIPY----GMSELYVIELNLSQNEISLIGED-LHQAPRLKILRLDENCLSLDEIKPSLL 210
+P G+ EL EL L NE+ + L P+L+ L L N +L E+ LL
Sbjct: 130 SLPLGALRGLGELQ--ELYLKGNELKTLPPGLLTPTPKLEKLSLANN--NLTELPAGLL 184
>AB086948-1|BAC10305.1| 626|Homo sapiens platelet glycoprotein Ib
alpha protein.
Length = 626
Score = 59.3 bits (137), Expect = 1e-08
Identities = 45/128 (35%), Positives = 68/128 (53%), Gaps = 3/128 (2%)
Frame = -2
Query: 731 CKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALP-ESLIN 555
C+L ++ +D VL LDLS N+L LP L L L++ N+L +LP +L
Sbjct: 81 CELTKLQVD--GTLPVLGTLDLSHNQLQSLPLLGQTLPALTVLDVSFNRLTSLPLGALRG 138
Query: 554 LKKLEVLNISNNFVQTLPV-CLKNLNNLKQVYASNNKLQAFPKQIL-GLQSLDVLDLSHN 381
L +L+ L + N ++TLP L L+++ +NN L P +L GL++LD L L N
Sbjct: 139 LGELQELYLKGNELKTLPPGLLTPTPKLEKLSLANNNLTELPAGLLNGLENLDTLLLQEN 198
Query: 380 KITEIPYG 357
+ IP G
Sbjct: 199 SLYTIPKG 206
Score = 52.8 bits (121), Expect = 1e-06
Identities = 41/119 (34%), Positives = 59/119 (49%), Gaps = 3/119 (2%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLP-DDLSKLKHLKQLNLDSNKLQALPESLIN- 555
+L+ +P+ + L LD+S N+L+ LP L L L++L L N+L+ LP L+
Sbjct: 104 QLQSLPL-LGQTLPALTVLDVSFNRLTSLPLGALRGLGELQELYLKGNELKTLPPGLLTP 162
Query: 554 LKKLEVLNISNNFVQTLPVCLKN-LNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHN 381
KLE L+++NN + LP L N L NL + N L PK G L L N
Sbjct: 163 TPKLEKLSLANNNLTELPAGLLNGLENLDTLLLQENSLYTIPKGFFGSHLLPFAFLHGN 221
Score = 46.8 bits (106), Expect = 8e-05
Identities = 54/179 (30%), Positives = 84/179 (46%), Gaps = 11/179 (6%)
Frame = -2
Query: 713 PIDVFSLCDVLR-----NLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALP-ESLINL 552
P+ +C+V + ++ K L+ LP DL K + L+L N L +L+
Sbjct: 13 PLHPHPICEVSKVASHLEVNCDKRNLTALPPDLPKDTTI--LHLSENLLYTFSLATLMPY 70
Query: 551 KKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKIT 372
+L LN+ + L V L L + S+N+LQ+ P L +L VLD+S N++T
Sbjct: 71 TRLTQLNLDRCELTKLQVD-GTLPVLGTLDLSHNQLQSLPLLGQTLPALTVLDVSFNRLT 129
Query: 371 EIPY----GMSELYVIELNLSQNEISLIGED-LHQAPRLKILRLDENCLSLDEIKPSLL 210
+P G+ EL EL L NE+ + L P+L+ L L N +L E+ LL
Sbjct: 130 SLPLGALRGLGELQ--ELYLKGNELKTLPPGLLTPTPKLEKLSLANN--NLTELPAGLL 184
>AB049405-1|BAB39854.1| 928|Homo sapiens VTS20631 protein.
Length = 928
Score = 59.3 bits (137), Expect = 1e-08
Identities = 50/161 (31%), Positives = 77/161 (47%), Gaps = 6/161 (3%)
Frame = -2
Query: 716 IPIDVFSLCDVLRNLDLSKNKLSVLP-DDLSKLKHLKQLNLDSNKLQALPE-SLINLKKL 543
+P F LR+L L N L+ +P L+ L L+ + L N++ +P+ + NL L
Sbjct: 114 VPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTSL 173
Query: 542 EVLNISNNFVQTLPV-CLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEI 366
VL++ NN +Q L + L+NL+ + + NKLQ FP I L L L +N I I
Sbjct: 174 VVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQEFPVAIRTLGRLQELGFHNNNIKAI 233
Query: 365 PYG--MSELYVIELNLSQNEISLIGEDLHQ-APRLKILRLD 252
P M + ++ N I +G Q P+L L L+
Sbjct: 234 PEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLSLN 274
Score = 58.8 bits (136), Expect = 2e-08
Identities = 51/166 (30%), Positives = 82/166 (49%), Gaps = 6/166 (3%)
Frame = -2
Query: 734 DCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPD-DLSKLKHLKQLNLDSNKLQAL-PESL 561
D L EIP+ + L+ + L+ N++S +PD L L L+L +N++Q L S
Sbjct: 132 DNALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSF 191
Query: 560 INLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFP-KQILGLQSLDVLDLSH 384
L LE L+++ N +Q PV ++ L L+++ NN ++A P K +G L +
Sbjct: 192 EGLHNLETLDLNYNKLQEFPVAIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYD 251
Query: 383 NKITEIPYGMSELYVIELN-LSQNEISLIGE--DLHQAPRLKILRL 255
N I + + Y+ +L+ LS N I E DL L+IL L
Sbjct: 252 NPIQFVGRSAFQ-YLPKLHTLSLNGAMDIQEFPDLKGTTSLEILTL 296
Score = 53.6 bits (123), Expect = 7e-07
Identities = 57/214 (26%), Positives = 96/214 (44%), Gaps = 30/214 (14%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVLPDD-LSKLKHLKQLNLDSNKLQALPE------ 567
L IP FS L+ L L N+L +P + L +L L+ L LD+N + +PE
Sbjct: 63 LSHIPGQAFSGLYSLKILMLQNNQLGGIPAEALWELPSLQSLRLDANLISLVPERSFEGL 122
Query: 566 -------------------SLINLKKLEVLNISNNFVQTLP-VCLKNLNNLKQVYASNNK 447
+L NL L+ + ++ N + +P +NL +L ++ NN+
Sbjct: 123 SSLRHLWLDDNALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNR 182
Query: 446 LQAF-PKQILGLQSLDVLDLSHNKITEIPYGMSEL-YVIELNLSQNEISLIGEDLHQA-P 276
+Q GL +L+ LDL++NK+ E P + L + EL N I I E P
Sbjct: 183 IQHLGTHSFEGLHNLETLDLNYNKLQEFPVAIRTLGRLQELGFHNNNIKAIPEKAFMGNP 242
Query: 275 RLKILRLDENCLSLDEIKPSLLRDSKIHTVSVDG 174
L+ + +N + + + K+HT+S++G
Sbjct: 243 LLQTIHFYDNPIQFVG-RSAFQYLPKLHTLSLNG 275
Score = 49.2 bits (112), Expect = 2e-05
Identities = 42/151 (27%), Positives = 75/151 (49%), Gaps = 5/151 (3%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPE-SLINLKKLEVLNISNNFVQT 507
L LDL+ NKL P + L L++L +N ++A+PE + + L+ ++ +N +Q
Sbjct: 197 LETLDLNYNKLQEFPVAIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPIQF 256
Query: 506 L-PVCLKNLNNLKQVYASN-NKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELY--V 339
+ + L L + + +Q FP + G SL++L L+ I +P GM + +
Sbjct: 257 VGRSAFQYLPKLHTLSLNGAMDIQEFP-DLKGTTSLEILTLTRAGIRLLPSGMCQQLPRL 315
Query: 338 IELNLSQNEISLIGEDLHQAPRLKILRLDEN 246
L LS N+I + LH+ +L+ + L N
Sbjct: 316 RVLELSHNQIEEL-PSLHRCQKLEEIGLQHN 345
Score = 43.2 bits (97), Expect = 0.001
Identities = 47/174 (27%), Positives = 79/174 (45%), Gaps = 7/174 (4%)
Frame = -2
Query: 692 CDVLRNLDLSKNKL-SVLPDDLSKLKHLKQLNLDSNKLQAL-PESLINLKKLEVLNISNN 519
C L + L N++ + D S+L L+ L+L N ++++ PE+ L L L++++N
Sbjct: 334 CQKLEEIGLQHNRIWEIGADTFSQLSSLQALDLSWNAIRSIHPEAFSTLHSLVKLDLTDN 393
Query: 518 FVQTLPVCLKNLNNLKQVYASNNKL--QAFPKQILGLQSLDVLDLSHNKITEIPYGM-SE 348
+ TLP L L L + N QAF K L +L++ + PYGM +
Sbjct: 394 QLTTLP--LAGLGGLMHLKLKGNLALSQAFSKD--SFPKLRILEVPY-AYQCCPYGMCAS 448
Query: 347 LYVIELNLSQNEISLIGEDLHQAPRLKILRLDENCL--SLDEIKPSLLRDSKIH 192
+ ++ L E+ + P + R EN LDE++ + DSK H
Sbjct: 449 FFKASGQWEAEDLHLDDEESSKRPLGLLARQAENHYDQDLDELQLE-MEDSKPH 501
Score = 36.7 bits (81), Expect = 0.087
Identities = 27/71 (38%), Positives = 37/71 (52%), Gaps = 1/71 (1%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKL-SVLPDDLSKLKHLKQLNLDSNKLQALPESLINL 552
++ EI D FS L+ LDLS N + S+ P+ S L L +L+L N+L LP L L
Sbjct: 346 RIWEIGADTFSQLSSLQALDLSWNAIRSIHPEAFSTLHSLVKLDLTDNQLTTLP--LAGL 403
Query: 551 KKLEVLNISNN 519
L L + N
Sbjct: 404 GGLMHLKLKGN 414
>BX537976-1|CAD97940.1| 693|Homo sapiens hypothetical protein
protein.
Length = 693
Score = 58.8 bits (136), Expect = 2e-08
Identities = 54/177 (30%), Positives = 81/177 (45%), Gaps = 8/177 (4%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLS---VLPDDLSKLKHLKQLNLDSNKLQALPESLIN 555
+ IP + F+ L LDLSKN ++ + P LK L +LN+D N L +P L +
Sbjct: 383 IASIPDEAFNGLPNLERLDLSKNNITSSGIGPKAFKLLKKLMRLNMDGNNLIQIPSQLPS 442
Query: 554 LKKLEVLNISNNFVQTL-PVCLKNLNNLKQVYASNNKL---QAFPKQILGLQSLDVLDLS 387
LE L ++ N +Q + L +LN L + N L P L+SL L L
Sbjct: 443 --TLEELKVNENNLQAIDEESLSDLNQLVTLELEGNNLSEANVNPLAFKPLKSLAYLRLG 500
Query: 386 HNKITEIPYGMSELYVIELNLSQNEISLIGE-DLHQAPRLKILRLDENCLSLDEIKP 219
NK IP G+ + EL L N+I I E + ++ ++ L N + + I P
Sbjct: 501 KNKFRIIPQGLPG-SIEELYLENNQIEEITEICFNHTRKINVIVLRYNKIEENRIAP 556
Score = 52.4 bits (120), Expect = 2e-06
Identities = 50/171 (29%), Positives = 82/171 (47%), Gaps = 11/171 (6%)
Frame = -2
Query: 710 IDVFSLCDV--LRNLDLSKNKLS---VLPDDLSKLKHLKQLNLDSNKLQALPESLINLKK 546
ID SL D+ L L+L N LS V P LK L L L NK + +P+ L
Sbjct: 457 IDEESLSDLNQLVTLELEGNNLSEANVNPLAFKPLKSLAYLRLGKNKFRIIPQGLPG--S 514
Query: 545 LEVLNISNNFVQTLP-VCLKNLNNLKQVYASNNKLQA---FPKQILGLQSLDVLDLSHNK 378
+E L + NN ++ + +C + + + NK++ P + ++L+ +DLS+NK
Sbjct: 515 IEELYLENNQIEEITEICFNHTRKINVIVLRYNKIEENRIAPLAWINQENLESIDLSYNK 574
Query: 377 ITEIPYGMSELYVIELNLSQNEISLIGEDL--HQAPRLKILRLDENCLSLD 231
+ +P + + ++ L L N+I I + H P L+ L L N L+ D
Sbjct: 575 LYHVPSYLPK-SLLHLVLLGNQIERIPGYVFGHMEPGLEYLYLSFNKLADD 624
>BC146759-1|AAI46760.1| 1523|Homo sapiens slit homolog 3
(Drosophila) protein.
Length = 1523
Score = 58.8 bits (136), Expect = 2e-08
Identities = 40/119 (33%), Positives = 64/119 (53%), Gaps = 4/119 (3%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLS-VLPDDLSKLKHLKQLNLDSNKLQALPESLIN-L 552
+K IP F+ L+ +D+SKN++S + PD LK L L L NK+ + + L + L
Sbjct: 319 IKAIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIAKGLFDGL 378
Query: 551 KKLEVLNISNNFVQTLPV-CLKNLNNLKQVYASNNKLQAFPKQILG-LQSLDVLDLSHN 381
L++L ++ N + L V ++L NL + +NKLQ K + LQS+ L L+ N
Sbjct: 379 VSLQLLLLNANKINCLRVNTFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQTLHLAQN 437
Score = 56.4 bits (130), Expect = 1e-07
Identities = 37/110 (33%), Positives = 60/110 (54%), Gaps = 4/110 (3%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDD-LSKLKHLKQLNLDSNKLQALPESLI-NLKKLEVLNISNNFVQ 510
LR L L N++SV+ LK L++L L+ NKLQ LPE L + KL L++S N +Q
Sbjct: 87 LRVLHLEDNQVSVIERGAFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQ 146
Query: 509 TLP-VCLKNLNNLKQVYASNNKLQAFPK-QILGLQSLDVLDLSHNKITEI 366
+P + + ++K + NN + L+ L++L L++N I+ I
Sbjct: 147 GIPRKAFRGITDVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNISRI 196
Score = 54.8 bits (126), Expect = 3e-07
Identities = 37/115 (32%), Positives = 59/115 (51%), Gaps = 3/115 (2%)
Frame = -2
Query: 692 CDVLRNLDLSKNK-LSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNF 516
C + + NK L LP + K + +L L+ N L A+P L L+ L ++++SNN
Sbjct: 729 CTCMETVVRCSNKGLRALPRGMPK--DVTELYLEGNHLTAVPRELSALRHLTLIDLSNNS 786
Query: 515 VQTLP-VCLKNLNNLKQVYASNNKLQAFPKQIL-GLQSLDVLDLSHNKITEIPYG 357
+ L N+++L + S N+L+ P GL+SL VL L N I+ +P G
Sbjct: 787 ISMLTNYTFSNMSHLSTLILSYNRLRCIPVHAFNGLRSLRVLTLHGNDISSVPEG 841
Score = 43.6 bits (98), Expect = 8e-04
Identities = 35/133 (26%), Positives = 68/133 (51%), Gaps = 5/133 (3%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDD--LSKLKHLKQLNLDSNKLQALPE 567
I DC +++ L + + +L L+ N++SVL KL +L+++NL +NK++ + E
Sbjct: 515 IVDCSNQKLVRIPSHLPEYVTDLRLNDNEVSVLEATGIFKKLPNLRKINLSNNKIKEVRE 574
Query: 566 SLIN-LKKLEVLNISNNFVQTL-PVCLKNLNNLKQVYASNNKLQAFPKQ-ILGLQSLDVL 396
+ ++ L ++ N ++T+ + L+ LK + +N + GL S+ +L
Sbjct: 575 GAFDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLMLRSNLIGCVSNDTFAGLSSVRLL 634
Query: 395 DLSHNKITEIPYG 357
L N+IT I G
Sbjct: 635 SLYDNRITTITPG 647
Score = 37.9 bits (84), Expect = 0.038
Identities = 27/102 (26%), Positives = 51/102 (50%), Gaps = 3/102 (2%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDL-SKLKHLKQLNLDSNKLQALP-E 567
+ D ++ I F L L L+KNKL VLP+ L L +L+L N++Q +P +
Sbjct: 92 LEDNQVSVIERGAFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRK 151
Query: 566 SLINLKKLEVLNISNNFVQTL-PVCLKNLNNLKQVYASNNKL 444
+ + ++ L + NN + + + L +L+ + +NN +
Sbjct: 152 AFRGITDVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNI 193
Score = 36.3 bits (80), Expect = 0.12
Identities = 34/117 (29%), Positives = 58/117 (49%), Gaps = 5/117 (4%)
Frame = -2
Query: 575 LPESLINLKKLEVLNISNNFVQTLPV-CLKNLNNLKQVYASNNKLQAF-PKQILGLQSLD 402
LPE ++ ++ + N ++ +P LK++ S N++ P GL+SL
Sbjct: 305 LPEGIVEIR------LEQNSIKAIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKSLT 358
Query: 401 VLDLSHNKITEIPYGMSE-LYVIE-LNLSQNEISLIGEDLHQ-APRLKILRLDENCL 240
L L NKITEI G+ + L ++ L L+ N+I+ + + Q L +L L +N L
Sbjct: 359 SLVLYGNKITEIAKGLFDGLVSLQLLLLNANKINCLRVNTFQDLQNLNLLSLYDNKL 415
>BC117190-1|AAI17191.1| 1529|Homo sapiens slit homolog 2
(Drosophila) protein.
Length = 1529
Score = 58.8 bits (136), Expect = 2e-08
Identities = 48/156 (30%), Positives = 77/156 (49%), Gaps = 8/156 (5%)
Frame = -2
Query: 674 LDLSKNKLS-VLPDDLSKLKHLKQLNLDSNKLQALPESLI-NLKKLEVLNISNNFVQTLP 501
LDL+ N ++ + D + L+HL+ L L NK+ + +LK+LE L ++ N +Q P
Sbjct: 60 LDLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNRNHLQLFP 119
Query: 500 VCL-KNLNNLKQVYASNNKLQAFP-KQILGLQSLDVLDLSHNKITEIPYG----MSELYV 339
L L ++ S N++QA P K G + L L +N+I+ I G + +L V
Sbjct: 120 ELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALRDLEV 179
Query: 338 IELNLSQNEISLIGEDLHQAPRLKILRLDENCLSLD 231
+ LN + N L + P+L+ RL N L D
Sbjct: 180 LTLN-NNNITRLSVASFNHMPKLRTFRLHSNNLYCD 214
Score = 58.4 bits (135), Expect = 3e-08
Identities = 42/119 (35%), Positives = 64/119 (53%), Gaps = 4/119 (3%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVL-PDDLSKLKHLKQLNLDSNKLQALPESLI-NL 552
+K IP FS LR +DLS N++S L PD L+ L L L NK+ LP+SL L
Sbjct: 312 IKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGL 371
Query: 551 KKLEVLNISNNFVQTLPV-CLKNLNNLKQVYASNNKLQAFPKQILG-LQSLDVLDLSHN 381
L++L ++ N + L V ++L+NL + +NKLQ K L+++ + L+ N
Sbjct: 372 FSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTFSPLRAIQTMHLAQN 430
Score = 56.8 bits (131), Expect = 8e-08
Identities = 38/115 (33%), Positives = 60/115 (52%), Gaps = 3/115 (2%)
Frame = -2
Query: 692 CDVLRNLDLSKNK-LSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNF 516
C L + NK L VLP + + + +L LD N+ +P+ L N K L ++++SNN
Sbjct: 731 CTCLDTVVRCSNKGLKVLPKGIPR--DVTELYLDGNQFTLVPKELSNYKHLTLIDLSNNR 788
Query: 515 VQTLP-VCLKNLNNLKQVYASNNKLQAFPKQIL-GLQSLDVLDLSHNKITEIPYG 357
+ TL N+ L + S N+L+ P + GL+SL +L L N I+ +P G
Sbjct: 789 ISTLSNQSFSNMTQLLTLILSYNRLRCIPPRTFDGLKSLRLLSLHGNDISVVPEG 843
Score = 49.6 bits (113), Expect = 1e-05
Identities = 41/148 (27%), Positives = 76/148 (51%), Gaps = 6/148 (4%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDD-LSKLKHLKQLNLDSNKLQAL-PE 567
I DC+ K + +L + + + L +N + V+P S K L++++L +N++ L P+
Sbjct: 283 IVDCRGKGLTEIPTNLPETITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPD 342
Query: 566 SLINLKKLEVLNISNNFVQTLPVCL-KNLNNLKQVYASNNKLQAFPKQIL-GLQSLDVLD 393
+ L+ L L + N + LP L + L +L+ + + NK+ L +L++L
Sbjct: 343 AFQGLRSLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLS 402
Query: 392 LSHNKITEIPYG-MSELYVIE-LNLSQN 315
L NK+ I G S L I+ ++L+QN
Sbjct: 403 LYDNKLQTIAKGTFSPLRAIQTMHLAQN 430
Score = 44.0 bits (99), Expect = 6e-04
Identities = 40/156 (25%), Positives = 77/156 (49%), Gaps = 12/156 (7%)
Frame = -2
Query: 674 LDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLI--NLKKLEVLNISNNFVQTLP 501
+D S KL+ +P+ + + + +L L++N+ L + I L +L +N SNN + +
Sbjct: 517 VDCSNQKLNKIPEHIPQ--YTAELRLNNNEFTVLEATGIFKKLPQLRKINFSNNKITDIE 574
Query: 500 V-CLKNLNNLKQVYASNNKLQAFP-KQILGLQSLDVLDLSHNKITEIP----YGMSELYV 339
+ + + ++ ++N+L+ K GL+SL L L N+IT + G+S + +
Sbjct: 575 EGAFEGASGVNEILLTSNRLENVQHKMFKGLESLKTLMLRSNRITCVGNDSFIGLSSVRL 634
Query: 338 IELNLSQNEISLIG----EDLHQAPRLKILRLDENC 243
L+L N+I+ + + LH L +L NC
Sbjct: 635 --LSLYDNQITTVAPGAFDTLHSLSTLNLLANPFNC 668
Score = 41.5 bits (93), Expect = 0.003
Identities = 36/120 (30%), Positives = 62/120 (51%), Gaps = 6/120 (5%)
Frame = -2
Query: 581 QALPESLINLKK-LEVLNISNNFVQTLPV-CLKNLNNLKQVYASNNKLQAF-PKQILGLQ 411
+ L E NL + + + + N ++ +P L+++ SNN++ P GL+
Sbjct: 289 KGLTEIPTNLPETITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLR 348
Query: 410 SLDVLDLSHNKITEIPYGMSE-LYVIE-LNLSQNEISLIGEDLHQ-APRLKILRLDENCL 240
SL+ L L NKITE+P + E L+ ++ L L+ N+I+ + D Q L +L L +N L
Sbjct: 349 SLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKL 408
>BC107493-1|AAI07494.1| 699|Homo sapiens extracellular matrix
protein 2, female organ and adipocyte specific protein.
Length = 699
Score = 58.8 bits (136), Expect = 2e-08
Identities = 54/177 (30%), Positives = 81/177 (45%), Gaps = 8/177 (4%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLS---VLPDDLSKLKHLKQLNLDSNKLQALPESLIN 555
+ IP + F+ L LDLSKN ++ + P LK L +LN+D N L +P L +
Sbjct: 355 IASIPDEAFNGLPNLERLDLSKNNITSSGIGPKAFKLLKKLMRLNMDGNNLIQIPSQLPS 414
Query: 554 LKKLEVLNISNNFVQTL-PVCLKNLNNLKQVYASNNKL---QAFPKQILGLQSLDVLDLS 387
LE L ++ N +Q + L +LN L + N L P L+SL L L
Sbjct: 415 --TLEELKVNENNLQAIDEESLSDLNQLVTLELEGNNLSEANVNPLAFKPLKSLAYLRLG 472
Query: 386 HNKITEIPYGMSELYVIELNLSQNEISLIGE-DLHQAPRLKILRLDENCLSLDEIKP 219
NK IP G+ + EL L N+I I E + ++ ++ L N + + I P
Sbjct: 473 KNKFRIIPQGLPG-SIEELYLENNQIEEITEICFNHTRKINVIVLRYNKIEENRIAP 528
Score = 52.4 bits (120), Expect = 2e-06
Identities = 50/171 (29%), Positives = 82/171 (47%), Gaps = 11/171 (6%)
Frame = -2
Query: 710 IDVFSLCDV--LRNLDLSKNKLS---VLPDDLSKLKHLKQLNLDSNKLQALPESLINLKK 546
ID SL D+ L L+L N LS V P LK L L L NK + +P+ L
Sbjct: 429 IDEESLSDLNQLVTLELEGNNLSEANVNPLAFKPLKSLAYLRLGKNKFRIIPQGLPG--S 486
Query: 545 LEVLNISNNFVQTLP-VCLKNLNNLKQVYASNNKLQA---FPKQILGLQSLDVLDLSHNK 378
+E L + NN ++ + +C + + + NK++ P + ++L+ +DLS+NK
Sbjct: 487 IEELYLENNQIEEITEICFNHTRKINVIVLRYNKIEENRIAPLAWINQENLESIDLSYNK 546
Query: 377 ITEIPYGMSELYVIELNLSQNEISLIGEDL--HQAPRLKILRLDENCLSLD 231
+ +P + + ++ L L N+I I + H P L+ L L N L+ D
Sbjct: 547 LYHVPSYLPK-SLLHLVLLGNQIERIPGYVFGHMEPGLEYLYLSFNKLADD 596
>AY358884-1|AAQ89243.1| 1523|Homo sapiens SLIT3 protein.
Length = 1523
Score = 58.8 bits (136), Expect = 2e-08
Identities = 40/119 (33%), Positives = 64/119 (53%), Gaps = 4/119 (3%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLS-VLPDDLSKLKHLKQLNLDSNKLQALPESLIN-L 552
+K IP F+ L+ +D+SKN++S + PD LK L L L NK+ + + L + L
Sbjct: 319 IKAIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIAKGLFDGL 378
Query: 551 KKLEVLNISNNFVQTLPV-CLKNLNNLKQVYASNNKLQAFPKQILG-LQSLDVLDLSHN 381
L++L ++ N + L V ++L NL + +NKLQ K + LQS+ L L+ N
Sbjct: 379 VSLQLLLLNANKINCLRVNTFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQTLHLAQN 437
Score = 56.4 bits (130), Expect = 1e-07
Identities = 37/110 (33%), Positives = 60/110 (54%), Gaps = 4/110 (3%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDD-LSKLKHLKQLNLDSNKLQALPESLI-NLKKLEVLNISNNFVQ 510
LR L L N++SV+ LK L++L L+ NKLQ LPE L + KL L++S N +Q
Sbjct: 87 LRVLHLEDNQVSVIERGAFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQ 146
Query: 509 TLP-VCLKNLNNLKQVYASNNKLQAFPK-QILGLQSLDVLDLSHNKITEI 366
+P + + ++K + NN + L+ L++L L++N I+ I
Sbjct: 147 GIPRKAFRGITDVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNISRI 196
Score = 54.8 bits (126), Expect = 3e-07
Identities = 37/115 (32%), Positives = 59/115 (51%), Gaps = 3/115 (2%)
Frame = -2
Query: 692 CDVLRNLDLSKNK-LSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNF 516
C + + NK L LP + K + +L L+ N L A+P L L+ L ++++SNN
Sbjct: 729 CTCMETVVRCSNKGLRALPRGMPK--DVTELYLEGNHLTAVPRELSALRHLTLIDLSNNS 786
Query: 515 VQTLP-VCLKNLNNLKQVYASNNKLQAFPKQIL-GLQSLDVLDLSHNKITEIPYG 357
+ L N+++L + S N+L+ P GL+SL VL L N I+ +P G
Sbjct: 787 ISMLTNYTFSNMSHLSTLILSYNRLRCIPVHAFNGLRSLRVLTLHGNDISSVPEG 841
Score = 44.4 bits (100), Expect = 4e-04
Identities = 35/133 (26%), Positives = 68/133 (51%), Gaps = 5/133 (3%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDD--LSKLKHLKQLNLDSNKLQALPE 567
I DC +++ L + + +L L+ N++SVL KL +L+++NL +NK++ + E
Sbjct: 515 IVDCSNQKLVRIPSHLPEYVTDLRLNDNEVSVLEATGIFKKLPNLRKINLSNNKIKEVRE 574
Query: 566 SLIN-LKKLEVLNISNNFVQTL-PVCLKNLNNLKQVYASNNKLQAFPKQ-ILGLQSLDVL 396
+ ++ L ++ N ++T+ + L+ LK + +N + GL S+ +L
Sbjct: 575 GAFDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLMLRSNLISCVSNDTFAGLSSVRLL 634
Query: 395 DLSHNKITEIPYG 357
L N+IT I G
Sbjct: 635 SLYDNRITTITPG 647
Score = 37.9 bits (84), Expect = 0.038
Identities = 27/102 (26%), Positives = 51/102 (50%), Gaps = 3/102 (2%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDL-SKLKHLKQLNLDSNKLQALP-E 567
+ D ++ I F L L L+KNKL VLP+ L L +L+L N++Q +P +
Sbjct: 92 LEDNQVSVIERGAFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRK 151
Query: 566 SLINLKKLEVLNISNNFVQTL-PVCLKNLNNLKQVYASNNKL 444
+ + ++ L + NN + + + L +L+ + +NN +
Sbjct: 152 AFRGITDVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNI 193
Score = 36.3 bits (80), Expect = 0.12
Identities = 34/117 (29%), Positives = 58/117 (49%), Gaps = 5/117 (4%)
Frame = -2
Query: 575 LPESLINLKKLEVLNISNNFVQTLPV-CLKNLNNLKQVYASNNKLQAF-PKQILGLQSLD 402
LPE ++ ++ + N ++ +P LK++ S N++ P GL+SL
Sbjct: 305 LPEGIVEIR------LEQNSIKAIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKSLT 358
Query: 401 VLDLSHNKITEIPYGMSE-LYVIE-LNLSQNEISLIGEDLHQ-APRLKILRLDENCL 240
L L NKITEI G+ + L ++ L L+ N+I+ + + Q L +L L +N L
Sbjct: 359 SLVLYGNKITEIAKGLFDGLVSLQLLLLNANKINCLRVNTFQDLQNLNLLSLYDNKL 415
>AL157827-4|CAI12589.1| 699|Homo sapiens extracellular matrix
protein 2, female organ and adipocyte specific protein.
Length = 699
Score = 58.8 bits (136), Expect = 2e-08
Identities = 54/177 (30%), Positives = 81/177 (45%), Gaps = 8/177 (4%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLS---VLPDDLSKLKHLKQLNLDSNKLQALPESLIN 555
+ IP + F+ L LDLSKN ++ + P LK L +LN+D N L +P L +
Sbjct: 355 IASIPDEAFNGLPNLERLDLSKNNITSSGIGPKAFKLLKKLMRLNMDGNNLIQIPSQLPS 414
Query: 554 LKKLEVLNISNNFVQTL-PVCLKNLNNLKQVYASNNKL---QAFPKQILGLQSLDVLDLS 387
LE L ++ N +Q + L +LN L + N L P L+SL L L
Sbjct: 415 --TLEELKVNENNLQAIDEESLSDLNQLVTLELEGNNLSEANVNPLAFKPLKSLAYLRLG 472
Query: 386 HNKITEIPYGMSELYVIELNLSQNEISLIGE-DLHQAPRLKILRLDENCLSLDEIKP 219
NK IP G+ + EL L N+I I E + ++ ++ L N + + I P
Sbjct: 473 KNKFRIIPQGLPG-SIEELYLENNQIEEITEICFNHTRKINVIVLRYNKIEENRIAP 528
Score = 52.4 bits (120), Expect = 2e-06
Identities = 50/171 (29%), Positives = 82/171 (47%), Gaps = 11/171 (6%)
Frame = -2
Query: 710 IDVFSLCDV--LRNLDLSKNKLS---VLPDDLSKLKHLKQLNLDSNKLQALPESLINLKK 546
ID SL D+ L L+L N LS V P LK L L L NK + +P+ L
Sbjct: 429 IDEESLSDLNQLVTLELEGNNLSEANVNPLAFKPLKSLAYLRLGKNKFRIIPQGLPG--S 486
Query: 545 LEVLNISNNFVQTLP-VCLKNLNNLKQVYASNNKLQA---FPKQILGLQSLDVLDLSHNK 378
+E L + NN ++ + +C + + + NK++ P + ++L+ +DLS+NK
Sbjct: 487 IEELYLENNQIEEITEICFNHTRKINVIVLRYNKIEENRIAPLAWINQENLESIDLSYNK 546
Query: 377 ITEIPYGMSELYVIELNLSQNEISLIGEDL--HQAPRLKILRLDENCLSLD 231
+ +P + + ++ L L N+I I + H P L+ L L N L+ D
Sbjct: 547 LYHVPSYLPK-SLLHLVLLGNQIERIPGYVFGHMEPGLEYLYLSFNKLADD 596
>AL137848-1|CAI16693.1| 699|Homo sapiens extracellular matrix
protein 2, female organ and adipocyte specific protein.
Length = 699
Score = 58.8 bits (136), Expect = 2e-08
Identities = 54/177 (30%), Positives = 81/177 (45%), Gaps = 8/177 (4%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLS---VLPDDLSKLKHLKQLNLDSNKLQALPESLIN 555
+ IP + F+ L LDLSKN ++ + P LK L +LN+D N L +P L +
Sbjct: 355 IASIPDEAFNGLPNLERLDLSKNNITSSGIGPKAFKLLKKLMRLNMDGNNLIQIPSQLPS 414
Query: 554 LKKLEVLNISNNFVQTL-PVCLKNLNNLKQVYASNNKL---QAFPKQILGLQSLDVLDLS 387
LE L ++ N +Q + L +LN L + N L P L+SL L L
Sbjct: 415 --TLEELKVNENNLQAIDEESLSDLNQLVTLELEGNNLSEANVNPLAFKPLKSLAYLRLG 472
Query: 386 HNKITEIPYGMSELYVIELNLSQNEISLIGE-DLHQAPRLKILRLDENCLSLDEIKP 219
NK IP G+ + EL L N+I I E + ++ ++ L N + + I P
Sbjct: 473 KNKFRIIPQGLPG-SIEELYLENNQIEEITEICFNHTRKINVIVLRYNKIEENRIAP 528
Score = 52.4 bits (120), Expect = 2e-06
Identities = 50/171 (29%), Positives = 82/171 (47%), Gaps = 11/171 (6%)
Frame = -2
Query: 710 IDVFSLCDV--LRNLDLSKNKLS---VLPDDLSKLKHLKQLNLDSNKLQALPESLINLKK 546
ID SL D+ L L+L N LS V P LK L L L NK + +P+ L
Sbjct: 429 IDEESLSDLNQLVTLELEGNNLSEANVNPLAFKPLKSLAYLRLGKNKFRIIPQGLPG--S 486
Query: 545 LEVLNISNNFVQTLP-VCLKNLNNLKQVYASNNKLQA---FPKQILGLQSLDVLDLSHNK 378
+E L + NN ++ + +C + + + NK++ P + ++L+ +DLS+NK
Sbjct: 487 IEELYLENNQIEEITEICFNHTRKINVIVLRYNKIEENRIAPLAWINQENLESIDLSYNK 546
Query: 377 ITEIPYGMSELYVIELNLSQNEISLIGEDL--HQAPRLKILRLDENCLSLD 231
+ +P + + ++ L L N+I I + H P L+ L L N L+ D
Sbjct: 547 LYHVPSYLPK-SLLHLVLLGNQIERIPGYVFGHMEPGLEYLYLSFNKLADD 596
>AF133270-1|AAD25539.1| 1525|Homo sapiens SLIT2 protein.
Length = 1525
Score = 58.8 bits (136), Expect = 2e-08
Identities = 48/156 (30%), Positives = 77/156 (49%), Gaps = 8/156 (5%)
Frame = -2
Query: 674 LDLSKNKLS-VLPDDLSKLKHLKQLNLDSNKLQALPESLI-NLKKLEVLNISNNFVQTLP 501
LDL+ N ++ + D + L+HL+ L L NK+ + +LK+LE L ++ N +Q P
Sbjct: 60 LDLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNRNHLQLFP 119
Query: 500 VCL-KNLNNLKQVYASNNKLQAFP-KQILGLQSLDVLDLSHNKITEIPYG----MSELYV 339
L L ++ S N++QA P K G + L L +N+I+ I G + +L V
Sbjct: 120 ELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALRDLEV 179
Query: 338 IELNLSQNEISLIGEDLHQAPRLKILRLDENCLSLD 231
+ LN + N L + P+L+ RL N L D
Sbjct: 180 LTLN-NNNITRLSVASFNHMPKLRTFRLHSNNLYCD 214
Score = 58.4 bits (135), Expect = 3e-08
Identities = 42/119 (35%), Positives = 64/119 (53%), Gaps = 4/119 (3%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVL-PDDLSKLKHLKQLNLDSNKLQALPESLI-NL 552
+K IP FS LR +DLS N++S L PD L+ L L L NK+ LP+SL L
Sbjct: 316 IKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGL 375
Query: 551 KKLEVLNISNNFVQTLPV-CLKNLNNLKQVYASNNKLQAFPKQILG-LQSLDVLDLSHN 381
L++L ++ N + L V ++L+NL + +NKLQ K L+++ + L+ N
Sbjct: 376 FSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTFSPLRAIQTMHLAQN 434
Score = 56.8 bits (131), Expect = 8e-08
Identities = 38/115 (33%), Positives = 60/115 (52%), Gaps = 3/115 (2%)
Frame = -2
Query: 692 CDVLRNLDLSKNK-LSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNF 516
C L + NK L VLP + + + +L LD N+ +P+ L N K L ++++SNN
Sbjct: 727 CTCLDTVVRCSNKGLKVLPKGIPR--DVTELYLDGNQFTLVPKELSNYKHLTLIDLSNNR 784
Query: 515 VQTLP-VCLKNLNNLKQVYASNNKLQAFPKQIL-GLQSLDVLDLSHNKITEIPYG 357
+ TL N+ L + S N+L+ P + GL+SL +L L N I+ +P G
Sbjct: 785 ISTLSNQSFSNMTQLLTLILSYNRLRCIPPRTFDGLKSLRLLSLHGNDISVVPEG 839
Score = 49.6 bits (113), Expect = 1e-05
Identities = 41/148 (27%), Positives = 76/148 (51%), Gaps = 6/148 (4%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDD-LSKLKHLKQLNLDSNKLQAL-PE 567
I DC+ K + +L + + + L +N + V+P S K L++++L +N++ L P+
Sbjct: 287 IVDCRGKGLTEIPTNLPETITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPD 346
Query: 566 SLINLKKLEVLNISNNFVQTLPVCL-KNLNNLKQVYASNNKLQAFPKQIL-GLQSLDVLD 393
+ L+ L L + N + LP L + L +L+ + + NK+ L +L++L
Sbjct: 347 AFQGLRSLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLS 406
Query: 392 LSHNKITEIPYG-MSELYVIE-LNLSQN 315
L NK+ I G S L I+ ++L+QN
Sbjct: 407 LYDNKLQTIAKGTFSPLRAIQTMHLAQN 434
Score = 44.0 bits (99), Expect = 6e-04
Identities = 40/156 (25%), Positives = 77/156 (49%), Gaps = 12/156 (7%)
Frame = -2
Query: 674 LDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLI--NLKKLEVLNISNNFVQTLP 501
+D S KL+ +P+ + + + +L L++N+ L + I L +L +N SNN + +
Sbjct: 513 VDCSNQKLNKIPEHIPQ--YTAELRLNNNEFTVLEATGIFKKLPQLRKINFSNNKITDIE 570
Query: 500 V-CLKNLNNLKQVYASNNKLQAFP-KQILGLQSLDVLDLSHNKITEIP----YGMSELYV 339
+ + + ++ ++N+L+ K GL+SL L L N+IT + G+S + +
Sbjct: 571 EGAFEGASGVNEILLTSNRLENVQHKMFKGLESLKTLMLRSNRITCVGNDSFIGLSSVRL 630
Query: 338 IELNLSQNEISLIG----EDLHQAPRLKILRLDENC 243
L+L N+I+ + + LH L +L NC
Sbjct: 631 --LSLYDNQITTVAPGAFDTLHSLSTLNLLANPFNC 664
Score = 41.5 bits (93), Expect = 0.003
Identities = 36/120 (30%), Positives = 62/120 (51%), Gaps = 6/120 (5%)
Frame = -2
Query: 581 QALPESLINLKK-LEVLNISNNFVQTLPV-CLKNLNNLKQVYASNNKLQAF-PKQILGLQ 411
+ L E NL + + + + N ++ +P L+++ SNN++ P GL+
Sbjct: 293 KGLTEIPTNLPETITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLR 352
Query: 410 SLDVLDLSHNKITEIPYGMSE-LYVIE-LNLSQNEISLIGEDLHQ-APRLKILRLDENCL 240
SL+ L L NKITE+P + E L+ ++ L L+ N+I+ + D Q L +L L +N L
Sbjct: 353 SLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKL 412
>AF055585-1|AAD04309.1| 1521|Homo sapiens neurogenic extracellular
slit protein Slit2 protein.
Length = 1521
Score = 58.8 bits (136), Expect = 2e-08
Identities = 48/156 (30%), Positives = 77/156 (49%), Gaps = 8/156 (5%)
Frame = -2
Query: 674 LDLSKNKLS-VLPDDLSKLKHLKQLNLDSNKLQALPESLI-NLKKLEVLNISNNFVQTLP 501
LDL+ N ++ + D + L+HL+ L L NK+ + +LK+LE L ++ N +Q P
Sbjct: 60 LDLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNRNHLQLFP 119
Query: 500 VCL-KNLNNLKQVYASNNKLQAFP-KQILGLQSLDVLDLSHNKITEIPYG----MSELYV 339
L L ++ S N++QA P K G + L L +N+I+ I G + +L V
Sbjct: 120 ELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALRDLEV 179
Query: 338 IELNLSQNEISLIGEDLHQAPRLKILRLDENCLSLD 231
+ LN + N L + P+L+ RL N L D
Sbjct: 180 LTLN-NNNITRLSVASFNHMPKLRTFRLHSNNLYCD 214
Score = 58.4 bits (135), Expect = 3e-08
Identities = 42/119 (35%), Positives = 64/119 (53%), Gaps = 4/119 (3%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVL-PDDLSKLKHLKQLNLDSNKLQALPESLI-NL 552
+K IP FS LR +DLS N++S L PD L+ L L L NK+ LP+SL L
Sbjct: 312 IKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGL 371
Query: 551 KKLEVLNISNNFVQTLPV-CLKNLNNLKQVYASNNKLQAFPKQILG-LQSLDVLDLSHN 381
L++L ++ N + L V ++L+NL + +NKLQ K L+++ + L+ N
Sbjct: 372 FSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTFSPLRAIQTMHLAQN 430
Score = 56.8 bits (131), Expect = 8e-08
Identities = 38/115 (33%), Positives = 60/115 (52%), Gaps = 3/115 (2%)
Frame = -2
Query: 692 CDVLRNLDLSKNK-LSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNF 516
C L + NK L VLP + + + +L LD N+ +P+ L N K L ++++SNN
Sbjct: 723 CTCLDTVVRCSNKGLKVLPKGIPR--DVTELYLDGNQFTLVPKELSNYKHLTLIDLSNNR 780
Query: 515 VQTLP-VCLKNLNNLKQVYASNNKLQAFPKQIL-GLQSLDVLDLSHNKITEIPYG 357
+ TL N+ L + S N+L+ P + GL+SL +L L N I+ +P G
Sbjct: 781 ISTLSNQSFSNMTQLLTLILSYNRLRCIPPRTFDGLKSLRLLSLHGNDISVVPEG 835
Score = 49.6 bits (113), Expect = 1e-05
Identities = 41/148 (27%), Positives = 76/148 (51%), Gaps = 6/148 (4%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDD-LSKLKHLKQLNLDSNKLQAL-PE 567
I DC+ K + +L + + + L +N + V+P S K L++++L +N++ L P+
Sbjct: 283 IVDCRGKGLTEIPTNLPETITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPD 342
Query: 566 SLINLKKLEVLNISNNFVQTLPVCL-KNLNNLKQVYASNNKLQAFPKQIL-GLQSLDVLD 393
+ L+ L L + N + LP L + L +L+ + + NK+ L +L++L
Sbjct: 343 AFQGLRSLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLS 402
Query: 392 LSHNKITEIPYG-MSELYVIE-LNLSQN 315
L NK+ I G S L I+ ++L+QN
Sbjct: 403 LYDNKLQTIAKGTFSPLRAIQTMHLAQN 430
Score = 41.5 bits (93), Expect = 0.003
Identities = 36/120 (30%), Positives = 62/120 (51%), Gaps = 6/120 (5%)
Frame = -2
Query: 581 QALPESLINLKK-LEVLNISNNFVQTLPV-CLKNLNNLKQVYASNNKLQAF-PKQILGLQ 411
+ L E NL + + + + N ++ +P L+++ SNN++ P GL+
Sbjct: 289 KGLTEIPTNLPETITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLR 348
Query: 410 SLDVLDLSHNKITEIPYGMSE-LYVIE-LNLSQNEISLIGEDLHQ-APRLKILRLDENCL 240
SL+ L L NKITE+P + E L+ ++ L L+ N+I+ + D Q L +L L +N L
Sbjct: 349 SLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKL 408
>AB017169-1|BAA35186.1| 1523|Homo sapiens Slit-3 protein protein.
Length = 1523
Score = 58.8 bits (136), Expect = 2e-08
Identities = 40/119 (33%), Positives = 64/119 (53%), Gaps = 4/119 (3%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLS-VLPDDLSKLKHLKQLNLDSNKLQALPESLIN-L 552
+K IP F+ L+ +D+SKN++S + PD LK L L L NK+ + + L + L
Sbjct: 319 IKAIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIAKGLFDGL 378
Query: 551 KKLEVLNISNNFVQTLPV-CLKNLNNLKQVYASNNKLQAFPKQILG-LQSLDVLDLSHN 381
L++L ++ N + L V ++L NL + +NKLQ K + LQS+ L L+ N
Sbjct: 379 VSLQLLLLNANKINCLRVNTFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQTLHLAQN 437
Score = 56.4 bits (130), Expect = 1e-07
Identities = 37/110 (33%), Positives = 60/110 (54%), Gaps = 4/110 (3%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDD-LSKLKHLKQLNLDSNKLQALPESLI-NLKKLEVLNISNNFVQ 510
LR L L N++SV+ LK L++L L+ NKLQ LPE L + KL L++S N +Q
Sbjct: 87 LRVLHLEDNQVSVIERGAFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQ 146
Query: 509 TLP-VCLKNLNNLKQVYASNNKLQAFPK-QILGLQSLDVLDLSHNKITEI 366
+P + + ++K + NN + L+ L++L L++N I+ I
Sbjct: 147 GIPRKAFRGITDVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNISRI 196
Score = 54.8 bits (126), Expect = 3e-07
Identities = 37/115 (32%), Positives = 59/115 (51%), Gaps = 3/115 (2%)
Frame = -2
Query: 692 CDVLRNLDLSKNK-LSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNF 516
C + + NK L LP + K + +L L+ N L A+P L L+ L ++++SNN
Sbjct: 729 CTCMETVVRCSNKGLRALPRGMPK--DVTELYLEGNHLTAVPRELSALRHLTLIDLSNNS 786
Query: 515 VQTLP-VCLKNLNNLKQVYASNNKLQAFPKQIL-GLQSLDVLDLSHNKITEIPYG 357
+ L N+++L + S N+L+ P GL+SL VL L N I+ +P G
Sbjct: 787 ISMLTNYTFSNMSHLSTLILSYNRLRCIPVHAFNGLRSLRVLTLHGNDISSVPEG 841
Score = 43.6 bits (98), Expect = 8e-04
Identities = 35/133 (26%), Positives = 68/133 (51%), Gaps = 5/133 (3%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDD--LSKLKHLKQLNLDSNKLQALPE 567
I DC +++ L + + +L L+ N++SVL KL +L+++NL +NK++ + E
Sbjct: 515 IVDCSNQKLVRIPSHLPEYVTDLRLNDNEVSVLEATGIFKKLPNLRKINLSNNKIKEVRE 574
Query: 566 SLIN-LKKLEVLNISNNFVQTL-PVCLKNLNNLKQVYASNNKLQAFPKQ-ILGLQSLDVL 396
+ ++ L ++ N ++T+ + L+ LK + +N + GL S+ +L
Sbjct: 575 GAFDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLMLRSNLIGCVSNDTFAGLSSVRLL 634
Query: 395 DLSHNKITEIPYG 357
L N+IT I G
Sbjct: 635 SLYDNRITTITPG 647
Score = 37.9 bits (84), Expect = 0.038
Identities = 27/102 (26%), Positives = 51/102 (50%), Gaps = 3/102 (2%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDL-SKLKHLKQLNLDSNKLQALP-E 567
+ D ++ I F L L L+KNKL VLP+ L L +L+L N++Q +P +
Sbjct: 92 LEDNQVSVIERGAFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRK 151
Query: 566 SLINLKKLEVLNISNNFVQTL-PVCLKNLNNLKQVYASNNKL 444
+ + ++ L + NN + + + L +L+ + +NN +
Sbjct: 152 AFRGITDVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNI 193
Score = 36.3 bits (80), Expect = 0.12
Identities = 34/117 (29%), Positives = 58/117 (49%), Gaps = 5/117 (4%)
Frame = -2
Query: 575 LPESLINLKKLEVLNISNNFVQTLPV-CLKNLNNLKQVYASNNKLQAF-PKQILGLQSLD 402
LPE ++ ++ + N ++ +P LK++ S N++ P GL+SL
Sbjct: 305 LPEGIVEIR------LEQNSIKAIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKSLT 358
Query: 401 VLDLSHNKITEIPYGMSE-LYVIE-LNLSQNEISLIGEDLHQ-APRLKILRLDENCL 240
L L NKITEI G+ + L ++ L L+ N+I+ + + Q L +L L +N L
Sbjct: 359 SLVLYGNKITEIAKGLFDGLVSLQLLLLNANKINCLRVNTFQDLQNLNLLSLYDNKL 415
>AB017168-1|BAA35185.1| 1529|Homo sapiens Slit-2 protein protein.
Length = 1529
Score = 58.8 bits (136), Expect = 2e-08
Identities = 48/156 (30%), Positives = 77/156 (49%), Gaps = 8/156 (5%)
Frame = -2
Query: 674 LDLSKNKLS-VLPDDLSKLKHLKQLNLDSNKLQALPESLI-NLKKLEVLNISNNFVQTLP 501
LDL+ N ++ + D + L+HL+ L L NK+ + +LK+LE L ++ N +Q P
Sbjct: 60 LDLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNRNHLQLFP 119
Query: 500 VCL-KNLNNLKQVYASNNKLQAFP-KQILGLQSLDVLDLSHNKITEIPYG----MSELYV 339
L L ++ S N++QA P K G + L L +N+I+ I G + +L V
Sbjct: 120 ELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALRDLEV 179
Query: 338 IELNLSQNEISLIGEDLHQAPRLKILRLDENCLSLD 231
+ LN + N L + P+L+ RL N L D
Sbjct: 180 LTLN-NNNITRLSVASFNHMPKLRTFRLHSNNLYCD 214
Score = 58.4 bits (135), Expect = 3e-08
Identities = 42/119 (35%), Positives = 64/119 (53%), Gaps = 4/119 (3%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLSVL-PDDLSKLKHLKQLNLDSNKLQALPESLI-NL 552
+K IP FS LR +DLS N++S L PD L+ L L L NK+ LP+SL L
Sbjct: 312 IKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGL 371
Query: 551 KKLEVLNISNNFVQTLPV-CLKNLNNLKQVYASNNKLQAFPKQILG-LQSLDVLDLSHN 381
L++L ++ N + L V ++L+NL + +NKLQ K L+++ + L+ N
Sbjct: 372 FSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTFSPLRAIQTMHLAQN 430
Score = 56.8 bits (131), Expect = 8e-08
Identities = 38/115 (33%), Positives = 60/115 (52%), Gaps = 3/115 (2%)
Frame = -2
Query: 692 CDVLRNLDLSKNK-LSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNF 516
C L + NK L VLP + + + +L LD N+ +P+ L N K L ++++SNN
Sbjct: 731 CTCLDTVVRCSNKGLKVLPKGIPR--DVTELYLDGNQFTLVPKELSNYKHLTLIDLSNNR 788
Query: 515 VQTLP-VCLKNLNNLKQVYASNNKLQAFPKQIL-GLQSLDVLDLSHNKITEIPYG 357
+ TL N+ L + S N+L+ P + GL+SL +L L N I+ +P G
Sbjct: 789 ISTLSNQSFSNMTQLLTLILSYNRLRCIPPRTFDGLKSLRLLSLHGNDISVVPEG 843
Score = 49.6 bits (113), Expect = 1e-05
Identities = 41/148 (27%), Positives = 76/148 (51%), Gaps = 6/148 (4%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDD-LSKLKHLKQLNLDSNKLQAL-PE 567
I DC+ K + +L + + + L +N + V+P S K L++++L +N++ L P+
Sbjct: 283 IVDCRGKGLTEIPTNLPETITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPD 342
Query: 566 SLINLKKLEVLNISNNFVQTLPVCL-KNLNNLKQVYASNNKLQAFPKQIL-GLQSLDVLD 393
+ L+ L L + N + LP L + L +L+ + + NK+ L +L++L
Sbjct: 343 AFQGLRSLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLS 402
Query: 392 LSHNKITEIPYG-MSELYVIE-LNLSQN 315
L NK+ I G S L I+ ++L+QN
Sbjct: 403 LYDNKLQTIAKGTFSPLRAIQTMHLAQN 430
Score = 44.0 bits (99), Expect = 6e-04
Identities = 40/156 (25%), Positives = 77/156 (49%), Gaps = 12/156 (7%)
Frame = -2
Query: 674 LDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLI--NLKKLEVLNISNNFVQTLP 501
+D S KL+ +P+ + + + +L L++N+ L + I L +L +N SNN + +
Sbjct: 517 VDCSNQKLNKIPEHIPQ--YTAELRLNNNEFTVLEATGIFKKLPQLRKINFSNNKITDIE 574
Query: 500 V-CLKNLNNLKQVYASNNKLQAFP-KQILGLQSLDVLDLSHNKITEIP----YGMSELYV 339
+ + + ++ ++N+L+ K GL+SL L L N+IT + G+S + +
Sbjct: 575 EGAFEGASGVNEILLTSNRLENVQHKMFKGLESLKTLMLRSNRITCVGNDSFIGLSSVRL 634
Query: 338 IELNLSQNEISLIG----EDLHQAPRLKILRLDENC 243
L+L N+I+ + + LH L +L NC
Sbjct: 635 --LSLYDNQITTVAPGAFDTLHSLSTLNLLANPFNC 668
Score = 41.5 bits (93), Expect = 0.003
Identities = 36/120 (30%), Positives = 62/120 (51%), Gaps = 6/120 (5%)
Frame = -2
Query: 581 QALPESLINLKK-LEVLNISNNFVQTLPV-CLKNLNNLKQVYASNNKLQAF-PKQILGLQ 411
+ L E NL + + + + N ++ +P L+++ SNN++ P GL+
Sbjct: 289 KGLTEIPTNLPETITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLR 348
Query: 410 SLDVLDLSHNKITEIPYGMSE-LYVIE-LNLSQNEISLIGEDLHQ-APRLKILRLDENCL 240
SL+ L L NKITE+P + E L+ ++ L L+ N+I+ + D Q L +L L +N L
Sbjct: 349 SLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKL 408
>AB011792-1|BAA33958.1| 699|Homo sapiens extracellular matrix
protein protein.
Length = 699
Score = 58.8 bits (136), Expect = 2e-08
Identities = 54/177 (30%), Positives = 81/177 (45%), Gaps = 8/177 (4%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLS---VLPDDLSKLKHLKQLNLDSNKLQALPESLIN 555
+ IP + F+ L LDLSKN ++ + P LK L +LN+D N L +P L +
Sbjct: 355 IASIPDEAFNGLPNLERLDLSKNNITSSGIGPKAFKLLKKLMRLNMDGNNLIQIPSQLPS 414
Query: 554 LKKLEVLNISNNFVQTL-PVCLKNLNNLKQVYASNNKL---QAFPKQILGLQSLDVLDLS 387
LE L ++ N +Q + L +LN L + N L P L+SL L L
Sbjct: 415 --TLEELKVNENNLQAIDEESLSDLNQLVTLELEGNNLSEANVNPLAFKPLKSLAYLRLG 472
Query: 386 HNKITEIPYGMSELYVIELNLSQNEISLIGE-DLHQAPRLKILRLDENCLSLDEIKP 219
NK IP G+ + EL L N+I I E + ++ ++ L N + + I P
Sbjct: 473 KNKFRIIPQGLPG-SIEELYLENNQIEEITEICFNHTRKINVIVLRYNKIEENRIAP 528
Score = 52.4 bits (120), Expect = 2e-06
Identities = 50/171 (29%), Positives = 82/171 (47%), Gaps = 11/171 (6%)
Frame = -2
Query: 710 IDVFSLCDV--LRNLDLSKNKLS---VLPDDLSKLKHLKQLNLDSNKLQALPESLINLKK 546
ID SL D+ L L+L N LS V P LK L L L NK + +P+ L
Sbjct: 429 IDEESLSDLNQLVTLELEGNNLSEANVNPLAFKPLKSLAYLRLGKNKFRIIPQGLPG--S 486
Query: 545 LEVLNISNNFVQTLP-VCLKNLNNLKQVYASNNKLQA---FPKQILGLQSLDVLDLSHNK 378
+E L + NN ++ + +C + + + NK++ P + ++L+ +DLS+NK
Sbjct: 487 IEELYLENNQIEEITEICFNHTRKINVIVLRYNKIEENRIAPLAWINQENLESIDLSYNK 546
Query: 377 ITEIPYGMSELYVIELNLSQNEISLIGEDL--HQAPRLKILRLDENCLSLD 231
+ +P + + ++ L L N+I I + H P L+ L L N L+ D
Sbjct: 547 LYHVPSYLPK-SLLHLVLLGNQIERIPGYVFGHMEPGLEYLYLSFNKLADD 596
>AB011538-1|BAA32466.2| 1559|Homo sapiens MEGF5 protein.
Length = 1559
Score = 58.8 bits (136), Expect = 2e-08
Identities = 40/119 (33%), Positives = 64/119 (53%), Gaps = 4/119 (3%)
Frame = -2
Query: 725 LKEIPIDVFSLCDVLRNLDLSKNKLS-VLPDDLSKLKHLKQLNLDSNKLQALPESLIN-L 552
+K IP F+ L+ +D+SKN++S + PD LK L L L NK+ + + L + L
Sbjct: 355 IKAIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIAKGLFDGL 414
Query: 551 KKLEVLNISNNFVQTLPV-CLKNLNNLKQVYASNNKLQAFPKQILG-LQSLDVLDLSHN 381
L++L ++ N + L V ++L NL + +NKLQ K + LQS+ L L+ N
Sbjct: 415 VSLQLLLLNANKINCLRVNTFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQTLHLAQN 473
Score = 56.4 bits (130), Expect = 1e-07
Identities = 37/110 (33%), Positives = 60/110 (54%), Gaps = 4/110 (3%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDD-LSKLKHLKQLNLDSNKLQALPESLI-NLKKLEVLNISNNFVQ 510
LR L L N++SV+ LK L++L L+ NKLQ LPE L + KL L++S N +Q
Sbjct: 123 LRVLHLEDNQVSVIERGAFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQ 182
Query: 509 TLP-VCLKNLNNLKQVYASNNKLQAFPK-QILGLQSLDVLDLSHNKITEI 366
+P + + ++K + NN + L+ L++L L++N I+ I
Sbjct: 183 GIPRKAFRGITDVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNISRI 232
Score = 54.8 bits (126), Expect = 3e-07
Identities = 37/115 (32%), Positives = 59/115 (51%), Gaps = 3/115 (2%)
Frame = -2
Query: 692 CDVLRNLDLSKNK-LSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNF 516
C + + NK L LP + K + +L L+ N L A+P L L+ L ++++SNN
Sbjct: 765 CTCMETVVRCSNKGLRALPRGMPK--DVTELYLEGNHLTAVPRELSALRHLTLIDLSNNS 822
Query: 515 VQTLP-VCLKNLNNLKQVYASNNKLQAFPKQIL-GLQSLDVLDLSHNKITEIPYG 357
+ L N+++L + S N+L+ P GL+SL VL L N I+ +P G
Sbjct: 823 ISMLTNYTFSNMSHLSTLILSYNRLRCIPVHAFNGLRSLRVLTLHGNDISSVPEG 877
Score = 43.6 bits (98), Expect = 8e-04
Identities = 35/133 (26%), Positives = 68/133 (51%), Gaps = 5/133 (3%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDD--LSKLKHLKQLNLDSNKLQALPE 567
I DC +++ L + + +L L+ N++SVL KL +L+++NL +NK++ + E
Sbjct: 551 IVDCSNQKLVRIPSHLPEYVTDLRLNDNEVSVLEATGIFKKLPNLRKINLSNNKIKEVRE 610
Query: 566 SLIN-LKKLEVLNISNNFVQTL-PVCLKNLNNLKQVYASNNKLQAFPKQ-ILGLQSLDVL 396
+ ++ L ++ N ++T+ + L+ LK + +N + GL S+ +L
Sbjct: 611 GAFDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLMLRSNLIGCVSNDTFAGLSSVRLL 670
Query: 395 DLSHNKITEIPYG 357
L N+IT I G
Sbjct: 671 SLYDNRITTITPG 683
Score = 37.9 bits (84), Expect = 0.038
Identities = 27/102 (26%), Positives = 51/102 (50%), Gaps = 3/102 (2%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDL-SKLKHLKQLNLDSNKLQALP-E 567
+ D ++ I F L L L+KNKL VLP+ L L +L+L N++Q +P +
Sbjct: 128 LEDNQVSVIERGAFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRK 187
Query: 566 SLINLKKLEVLNISNNFVQTL-PVCLKNLNNLKQVYASNNKL 444
+ + ++ L + NN + + + L +L+ + +NN +
Sbjct: 188 AFRGITDVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNI 229
Score = 36.3 bits (80), Expect = 0.12
Identities = 34/117 (29%), Positives = 58/117 (49%), Gaps = 5/117 (4%)
Frame = -2
Query: 575 LPESLINLKKLEVLNISNNFVQTLPV-CLKNLNNLKQVYASNNKLQAF-PKQILGLQSLD 402
LPE ++ ++ + N ++ +P LK++ S N++ P GL+SL
Sbjct: 341 LPEGIVEIR------LEQNSIKAIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKSLT 394
Query: 401 VLDLSHNKITEIPYGMSE-LYVIE-LNLSQNEISLIGEDLHQ-APRLKILRLDENCL 240
L L NKITEI G+ + L ++ L L+ N+I+ + + Q L +L L +N L
Sbjct: 395 SLVLYGNKITEIAKGLFDGLVSLQLLLLNANKINCLRVNTFQDLQNLNLLSLYDNKL 451
>DQ013130-1|AAY67799.1| 2014|Homo sapiens leucine-rich repeat kinase
1 protein.
Length = 2014
Score = 58.4 bits (135), Expect = 3e-08
Identities = 49/162 (30%), Positives = 79/162 (48%), Gaps = 9/162 (5%)
Frame = -2
Query: 695 LCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPE-----SLINLKKLEVLN 531
+C L +D+S NKLS LP L L++L N L+ L E + I L+KL+ L+
Sbjct: 326 ICSRLLEIDISSNKLSHLPPGFLHLSKLQKLTASKNCLEKLFEEENATNWIGLRKLQELD 385
Query: 530 ISNNFVQTLP-VCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGM 354
IS+N + LP + L + +L + S N L+ FP L S N + +P M
Sbjct: 386 ISDNKLTELPALFLHSFKSLNSLNVSRNNLKVFPDP--WACPLKCCKASRNALECLPDKM 443
Query: 353 S---ELYVIELNLSQNEISLIGEDLHQAPRLKILRLDENCLS 237
+ + ++ +++ S+N + + L Q L LRL N L+
Sbjct: 444 AVFWKNHLKDVDFSENALKEVPLGLFQLDALMFLRLQGNQLA 485
Score = 49.2 bits (112), Expect = 2e-05
Identities = 39/125 (31%), Positives = 62/125 (49%), Gaps = 3/125 (2%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESL 561
I+D KL E+P L +L++S+N L V PD + LK N L+ LP+ +
Sbjct: 386 ISDNKLTELPALFLHSFKSLNSLNVSRNNLKVFPDPWA--CPLKCCKASRNALECLPDKM 443
Query: 560 INLKK--LEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQ-ILGLQSLDVLDL 390
K L+ ++ S N ++ +P+ L L+ L + N+L A P Q + L LDL
Sbjct: 444 AVFWKNHLKDVDFSENALKEVPLGLFQLDALMFLRLQGNQLAALPPQEKWTCRQLKTLDL 503
Query: 389 SHNKI 375
S N++
Sbjct: 504 SRNQL 508
Score = 39.1 bits (87), Expect = 0.016
Identities = 33/117 (28%), Positives = 56/117 (47%), Gaps = 7/117 (5%)
Frame = -2
Query: 692 CDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPE-SLINL-----KKLEVLN 531
C L+ LDLS+N+L D L K K + + S++ + LEVL
Sbjct: 495 CRQLKTLDLSRNQLGKNEDGL-KTKRIAFFTTRGRQRSGTEAASVLEFPAFLSESLEVLC 553
Query: 530 ISNNFVQTLPVCLKNLNNLKQVYASNNK-LQAFPKQILGLQSLDVLDLSHNKITEIP 363
+++N + T+P + L +L ++Y NN L+ P ++ L +L LD I+ +P
Sbjct: 554 LNDNHLDTVPPSVCLLKSLSELYLGNNPGLRELPPELGQLGNLWQLDTEDLTISNVP 610
>BC025681-1|AAH25681.1| 605|Homo sapiens insulin-like growth factor
binding protein, acid labile subunit protein.
Length = 605
Score = 58.4 bits (135), Expect = 3e-08
Identities = 55/199 (27%), Positives = 100/199 (50%), Gaps = 9/199 (4%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLS-KLKHLKQLNLDSNKLQAL-PE 567
+A +L + +FS LR LDLS+N L + ++ +L L++L LD N + A+ P
Sbjct: 201 LAGNRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLPRLQKLYLDRNLIAAVAPG 260
Query: 566 SLINLKKLEVLNISNNFVQ-TLPVCLKNLNNLKQVYASNNKLQAF-PKQILGLQSLDVLD 393
+ + LK L L++S+N V L L L+ + S+N + + P+ L L+ L
Sbjct: 261 AFLGLKALRWLDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQ 320
Query: 392 LSHNKITEIP----YGMSELYVIELNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEI 225
L HN+I ++ G+ +L V+ L+ +Q + G L + ++ L NCL +
Sbjct: 321 LGHNRIRQLAERSFEGLGQLEVLTLDHNQLQEVKAGAFL-GLTNMAVMNLSGNCLR--NL 377
Query: 224 KPSLLRD-SKIHTVSVDGN 171
+ R K+H++ ++G+
Sbjct: 378 PEQVFRGLGKLHSLHLEGS 396
Score = 54.4 bits (125), Expect = 4e-07
Identities = 40/126 (31%), Positives = 69/126 (54%), Gaps = 4/126 (3%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSK-LKHLKQLNLDSNKLQALPES 564
+++ +L + +F L +L+L N L+VLPD + L L++L L N+L L +
Sbjct: 153 LSNNRLSRLEDGLFEGLGSLWDLNLGWNSLAVLPDAAFRGLGSLRELVLAGNRLAYLQPA 212
Query: 563 LIN-LKKLEVLNISNNFVQTLPV-CLKNLNNLKQVYASNNKLQAF-PKQILGLQSLDVLD 393
L + L +L L++S N ++ + L L+++Y N + A P LGL++L LD
Sbjct: 213 LFSGLAELRELDLSRNALRAIKANVFVQLPRLQKLYLDRNLIAAVAPGAFLGLKALRWLD 272
Query: 392 LSHNKI 375
LSHN++
Sbjct: 273 LSHNRV 278
Score = 46.0 bits (104), Expect = 1e-04
Identities = 35/96 (36%), Positives = 54/96 (56%), Gaps = 3/96 (3%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSK-LKHLKQLNLDSNKLQALP-ESLINLKKLEVLNISNNFVQ 510
L LDL+ N+L+ LP L + L L+ L L N+L LP ++L L++ L++S+N ++
Sbjct: 436 LLELDLTSNQLTHLPHRLFQGLGKLEYLLLSRNRLAELPADALGPLQRAFWLDVSHNRLE 495
Query: 509 TLP-VCLKNLNNLKQVYASNNKLQAFPKQILGLQSL 405
LP L L L+ + NN L+ F Q GL+ L
Sbjct: 496 ALPNSLLAPLGRLRYLSLRNNSLRTFTPQPPGLERL 531
Score = 31.9 bits (69), Expect = 2.5
Identities = 20/63 (31%), Positives = 32/63 (50%), Gaps = 1/63 (1%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDD-LSKLKHLKQLNLDSNKLQALPESLINL 552
+L E+P D LD+S N+L LP+ L+ L L+ L+L +N L+ L
Sbjct: 469 RLAELPADALGPLQRAFWLDVSHNRLEALPNSLLAPLGRLRYLSLRNNSLRTFTPQPPGL 528
Query: 551 KKL 543
++L
Sbjct: 529 ERL 531
>AK058188-1|BAB71707.1| 475|Homo sapiens protein ( Homo sapiens
cDNA FLJ25459 fis, clone TST09038. ).
Length = 475
Score = 58.4 bits (135), Expect = 3e-08
Identities = 34/126 (26%), Positives = 71/126 (56%)
Frame = -2
Query: 626 KLKHLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNK 447
K H +L + S ++++L SL +L L L++++N++ +P + L+NL + S+NK
Sbjct: 32 KKSHWAELEI-SGRVRSLSTSLWSLTHLTALHLNDNYLSRIPPDIAKLHNLVYLDLSSNK 90
Query: 446 LQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVIELNLSQNEISLIGEDLHQAPRLK 267
L++ P ++ + SL L L++N + +PY + L+ + LN + +++ E L P +
Sbjct: 91 LRSLPAELGNMVSLRELLLNNNLLRVLPYELGRLFQL-LNFMLDNLAVHPEQLPPRPWIT 149
Query: 266 ILRLDE 249
+ D+
Sbjct: 150 LKERDQ 155
Score = 56.4 bits (130), Expect = 1e-07
Identities = 36/102 (35%), Positives = 57/102 (55%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALPESLINLK 549
+++ + ++SL L L L+ N LS +P D++KL +L L+L SNKL++LP L N+
Sbjct: 44 RVRSLSTSLWSLTH-LTALHLNDNYLSRIPPDIAKLHNLVYLDLSSNKLRSLPAELGNMV 102
Query: 548 KLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQI 423
L L ++NN ++ LP L L L N L P+Q+
Sbjct: 103 SLRELLLNNNLLRVLPYELGRLFQLLNFMLDN--LAVHPEQL 142
>AB038516-1|BAB12038.1| 626|Homo sapiens platelet glycoprotein Ib
alpha protein.
Length = 626
Score = 58.4 bits (135), Expect = 3e-08
Identities = 45/128 (35%), Positives = 67/128 (52%), Gaps = 3/128 (2%)
Frame = -2
Query: 731 CKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALP-ESLIN 555
C+L + +D VL LDLS N+L LP L L L++ N+L +LP +L
Sbjct: 81 CELTKFQVD--GTLPVLGTLDLSHNQLQSLPLLGQTLPALTVLDVSFNRLTSLPLGALRG 138
Query: 554 LKKLEVLNISNNFVQTLPV-CLKNLNNLKQVYASNNKLQAFPKQIL-GLQSLDVLDLSHN 381
L +L+ L + N ++TLP L L+++ +NN L P +L GL++LD L L N
Sbjct: 139 LGELQELYLKGNELKTLPPGLLTPTPKLEKLSLANNNLTELPAGLLNGLENLDTLLLQEN 198
Query: 380 KITEIPYG 357
+ IP G
Sbjct: 199 SLYTIPKG 206
Score = 52.8 bits (121), Expect = 1e-06
Identities = 41/119 (34%), Positives = 59/119 (49%), Gaps = 3/119 (2%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLP-DDLSKLKHLKQLNLDSNKLQALPESLIN- 555
+L+ +P+ + L LD+S N+L+ LP L L L++L L N+L+ LP L+
Sbjct: 104 QLQSLPL-LGQTLPALTVLDVSFNRLTSLPLGALRGLGELQELYLKGNELKTLPPGLLTP 162
Query: 554 LKKLEVLNISNNFVQTLPVCLKN-LNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHN 381
KLE L+++NN + LP L N L NL + N L PK G L L N
Sbjct: 163 TPKLEKLSLANNNLTELPAGLLNGLENLDTLLLQENSLYTIPKGFFGSHLLPFAFLHGN 221
Score = 45.2 bits (102), Expect = 2e-04
Identities = 53/179 (29%), Positives = 83/179 (46%), Gaps = 11/179 (6%)
Frame = -2
Query: 713 PIDVFSLCDVLR-----NLDLSKNKLSVLPDDLSKLKHLKQLNLDSNKLQALP-ESLINL 552
P+ +C+V + ++ K L+ LP DL K + L+L N L +L+
Sbjct: 13 PLHPHPICEVSKVASHLEVNCDKRNLTALPPDLPKDTTI--LHLSENLLYTFSLATLMPY 70
Query: 551 KKLEVLNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKIT 372
+L LN+ + V L L + S+N+LQ+ P L +L VLD+S N++T
Sbjct: 71 TRLTQLNLDRCELTKFQVD-GTLPVLGTLDLSHNQLQSLPLLGQTLPALTVLDVSFNRLT 129
Query: 371 EIPY----GMSELYVIELNLSQNEISLIGED-LHQAPRLKILRLDENCLSLDEIKPSLL 210
+P G+ EL EL L NE+ + L P+L+ L L N +L E+ LL
Sbjct: 130 SLPLGALRGLGELQ--ELYLKGNELKTLPPGLLTPTPKLEKLSLANN--NLTELPAGLL 184
>M86826-1|AAA36047.1| 605|Homo sapiens insulin-like growth factor
binding protein complex protein.
Length = 605
Score = 58.0 bits (134), Expect = 3e-08
Identities = 55/199 (27%), Positives = 100/199 (50%), Gaps = 9/199 (4%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLS-KLKHLKQLNLDSNKLQAL-PE 567
+A +L + +FS LR LDLS+N L + ++ +L L++L LD N + A+ P
Sbjct: 201 LAGNRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLPRLQKLYLDRNLIAAVAPG 260
Query: 566 SLINLKKLEVLNISNNFVQ-TLPVCLKNLNNLKQVYASNNKLQAF-PKQILGLQSLDVLD 393
+ + LK L L++S+N V L L L+ + S+N + + P+ L L+ L
Sbjct: 261 AFLGLKALRWLDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQ 320
Query: 392 LSHNKITEIP----YGMSELYVIELNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEI 225
L HN+I ++ G+ +L V+ L+ +Q + G L + ++ L NCL +
Sbjct: 321 LGHNRIRQLAERSFEGLGQLEVLTLDHNQLQEVKAGAFL-GLTNVAVMNLSGNCLR--NL 377
Query: 224 KPSLLRD-SKIHTVSVDGN 171
+ R K+H++ ++G+
Sbjct: 378 PEQVFRGLGKLHSLHLEGS 396
Score = 54.4 bits (125), Expect = 4e-07
Identities = 40/126 (31%), Positives = 69/126 (54%), Gaps = 4/126 (3%)
Frame = -2
Query: 740 IADCKLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSK-LKHLKQLNLDSNKLQALPES 564
+++ +L + +F L +L+L N L+VLPD + L L++L L N+L L +
Sbjct: 153 LSNNRLSRLEDGLFEGLGSLWDLNLGWNSLAVLPDAAFRGLGSLRELVLAGNRLAYLQPA 212
Query: 563 LIN-LKKLEVLNISNNFVQTLPV-CLKNLNNLKQVYASNNKLQAF-PKQILGLQSLDVLD 393
L + L +L L++S N ++ + L L+++Y N + A P LGL++L LD
Sbjct: 213 LFSGLAELRELDLSRNALRAIKANVFVQLPRLQKLYLDRNLIAAVAPGAFLGLKALRWLD 272
Query: 392 LSHNKI 375
LSHN++
Sbjct: 273 LSHNRV 278
Score = 46.0 bits (104), Expect = 1e-04
Identities = 35/96 (36%), Positives = 54/96 (56%), Gaps = 3/96 (3%)
Frame = -2
Query: 683 LRNLDLSKNKLSVLPDDLSK-LKHLKQLNLDSNKLQALP-ESLINLKKLEVLNISNNFVQ 510
L LDL+ N+L+ LP L + L L+ L L N+L LP ++L L++ L++S+N ++
Sbjct: 436 LLELDLTSNQLTHLPHRLFQGLGKLEYLLLSRNRLAELPADALGPLQRAFWLDVSHNRLE 495
Query: 509 TLP-VCLKNLNNLKQVYASNNKLQAFPKQILGLQSL 405
LP L L L+ + NN L+ F Q GL+ L
Sbjct: 496 ALPNSLLAPLGRLRYLSLRNNSLRTFTPQPPGLERL 531
Score = 31.9 bits (69), Expect = 2.5
Identities = 20/63 (31%), Positives = 32/63 (50%), Gaps = 1/63 (1%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDD-LSKLKHLKQLNLDSNKLQALPESLINL 552
+L E+P D LD+S N+L LP+ L+ L L+ L+L +N L+ L
Sbjct: 469 RLAELPADALGPLQRAFWLDVSHNRLEALPNSLLAPLGRLRYLSLRNNSLRTFTPQPPGL 528
Query: 551 KKL 543
++L
Sbjct: 529 ERL 531
>M65153-1|AAA52287.1| 394|Homo sapiens biglycan protein.
Length = 394
Score = 58.0 bits (134), Expect = 3e-08
Identities = 49/174 (28%), Positives = 92/174 (52%), Gaps = 6/174 (3%)
Frame = -2
Query: 674 LDLSKNKLSVL-PDDLSKLKHLKQLNLDSNKLQALPESLIN-LKKLEVLNISNNFVQTLP 501
LDL N +S L DD L+HL L L +NK+ + E + L+ ++ L IS N + +P
Sbjct: 121 LDLQNNDISELRKDDFKGLQHLYALVLVNNKISKIHEKAFSPLRNVQKLYISKNHLVEIP 180
Query: 500 VCLKNLNNLKQVYASNNKLQAFPKQIL-GLQSLDVLDLSHNKITEI---PYGMSELYVIE 333
L ++L ++ +N+++ PK + GL++++ +++ N + P L +
Sbjct: 181 PNLP--SSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLKLNY 238
Query: 332 LNLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIHTVSVDGN 171
L +S+ +++ I +DL + L L LD N + E++ LLR SK++ + + N
Sbjct: 239 LRISEAKLTGIPKDLPET--LNELHLDHNKIQAIELE-DLLRYSKLYRLGLGHN 289
>BC113617-1|AAI13618.1| 757|Homo sapiens relaxin/insulin-like
family peptide receptor 1 protein.
Length = 757
Score = 58.0 bits (134), Expect = 3e-08
Identities = 46/151 (30%), Positives = 78/151 (51%), Gaps = 5/151 (3%)
Frame = -2
Query: 608 QLNLDSNKLQALPESLINLKKLEVLNISNNFVQTLPV-CLKNLNNLKQVYASNNKLQAFP 432
+L+ D L+A+P N+ +++ N ++ LP C KN ++L+++Y NNK+ +
Sbjct: 110 ELDCDETNLRAVPSVSSNVT---AMSLQWNLIRKLPPDCFKNYHDLQKLYLQNNKITSIS 166
Query: 431 -KQILGLQSLDVLDLSHNKITEIPYGMSE-LYVIE-LNLSQNEISLIG-EDLHQAPRLKI 264
GL SL L LSHN+IT + G+ E L+ +E L + N +S I + L +
Sbjct: 167 IYAFRGLNSLTKLYLSHNRITFLKPGVFEDLHRLEWLIIEDNHLSRISPPTFYGLNSLIL 226
Query: 263 LRLDENCLSLDEIKPSLLRDSKIHTVSVDGN 171
L L N L+ KP ++H + ++GN
Sbjct: 227 LVLMNNVLTRLPDKPLCQHMPRLHWLDLEGN 257
Score = 40.7 bits (91), Expect = 0.005
Identities = 47/159 (29%), Positives = 70/159 (44%), Gaps = 8/159 (5%)
Frame = -2
Query: 704 VFSLCDVLRNLDLSKNKLS-VLPDDLSKLKHLKQLNLDSNKLQALPESLI--NLKKLEVL 534
VF L L + N LS + P L L L L +N L LP+ + ++ +L L
Sbjct: 193 VFEDLHRLEWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWL 252
Query: 533 NISNNFVQTLP-VCLKNLNNLKQVYASNNKLQAFPKQILG-LQSLDVLDLSHNKITEI-P 363
++ N + L + + +NL + NK+ + LQ LD LDL NKI + P
Sbjct: 253 DLEGNHIHNLRNLTFISCSNLTVLVMRKNKINHLNENTFAPLQKLDELDLGSNKIENLPP 312
Query: 362 YGMSELYVI-ELNLSQNEISLI-GEDLHQAPRLKILRLD 252
+L + +LNLS N I I +LK L L+
Sbjct: 313 LIFKDLKELSQLNLSYNPIQKIQANQFDYLVKLKSLSLE 351
Score = 39.1 bits (87), Expect = 0.016
Identities = 30/94 (31%), Positives = 45/94 (47%), Gaps = 5/94 (5%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSK-LKHLKQLNLDSNKLQALP----ES 564
K+ + + F+ L LDL NK+ LP + K LK L QLNL N +Q + +
Sbjct: 282 KINHLNENTFAPLQKLDELDLGSNKIENLPPLIFKDLKELSQLNLSYNPIQKIQANQFDY 341
Query: 563 LINLKKLEVLNISNNFVQTLPVCLKNLNNLKQVY 462
L+ LK L + I + +Q + L NL +Y
Sbjct: 342 LVKLKSLSLEGIEISNIQQR--MFRPLMNLSHIY 373
>BC112142-1|AAI12143.1| 757|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 7 protein.
Length = 757
Score = 58.0 bits (134), Expect = 3e-08
Identities = 46/151 (30%), Positives = 78/151 (51%), Gaps = 5/151 (3%)
Frame = -2
Query: 608 QLNLDSNKLQALPESLINLKKLEVLNISNNFVQTLPV-CLKNLNNLKQVYASNNKLQAFP 432
+L+ D L+A+P N+ +++ N ++ LP C KN ++L+++Y NNK+ +
Sbjct: 110 ELDCDETNLRAVPSVSSNVT---AMSLQWNLIRKLPPDCFKNYHDLQKLYLQNNKITSIS 166
Query: 431 -KQILGLQSLDVLDLSHNKITEIPYGMSE-LYVIE-LNLSQNEISLIG-EDLHQAPRLKI 264
GL SL L LSHN+IT + G+ E L+ +E L + N +S I + L +
Sbjct: 167 IYAFRGLNSLTKLYLSHNRITFLKPGVFEDLHRLEWLIIEDNHLSRISPPTFYGLNSLIL 226
Query: 263 LRLDENCLSLDEIKPSLLRDSKIHTVSVDGN 171
L L N L+ KP ++H + ++GN
Sbjct: 227 LVLMNNVLTRLPDKPLCQHMPRLHWLDLEGN 257
Score = 40.7 bits (91), Expect = 0.005
Identities = 47/159 (29%), Positives = 70/159 (44%), Gaps = 8/159 (5%)
Frame = -2
Query: 704 VFSLCDVLRNLDLSKNKLS-VLPDDLSKLKHLKQLNLDSNKLQALPESLI--NLKKLEVL 534
VF L L + N LS + P L L L L +N L LP+ + ++ +L L
Sbjct: 193 VFEDLHRLEWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWL 252
Query: 533 NISNNFVQTLP-VCLKNLNNLKQVYASNNKLQAFPKQILG-LQSLDVLDLSHNKITEI-P 363
++ N + L + + +NL + NK+ + LQ LD LDL NKI + P
Sbjct: 253 DLEGNHIHNLRNLTFISCSNLTVLVMRKNKINHLNENTFAPLQKLDELDLGSNKIENLPP 312
Query: 362 YGMSELYVI-ELNLSQNEISLI-GEDLHQAPRLKILRLD 252
+L + +LNLS N I I +LK L L+
Sbjct: 313 LIFKDLKELSQLNLSYNPIQKIQANQFDYLVKLKSLSLE 351
Score = 39.1 bits (87), Expect = 0.016
Identities = 30/94 (31%), Positives = 45/94 (47%), Gaps = 5/94 (5%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSK-LKHLKQLNLDSNKLQALP----ES 564
K+ + + F+ L LDL NK+ LP + K LK L QLNL N +Q + +
Sbjct: 282 KINHLNENTFAPLQKLDELDLGSNKIENLPPLIFKDLKELSQLNLSYNPIQKIQANQFDY 341
Query: 563 LINLKKLEVLNISNNFVQTLPVCLKNLNNLKQVY 462
L+ LK L + I + +Q + L NL +Y
Sbjct: 342 LVKLKSLSLEGIEISNIQQR--MFRPLMNLSHIY 373
>BC030276-1|AAH30276.1| 529|Homo sapiens LOC220416 protein protein.
Length = 529
Score = 58.0 bits (134), Expect = 3e-08
Identities = 36/112 (32%), Positives = 61/112 (54%), Gaps = 2/112 (1%)
Frame = -2
Query: 635 DLSKLK-HLKQLNLDSNKLQALPESLINLKKLEVLNISNNFVQTLPVCLKNLNNLKQVYA 459
DL+ L L LNL N L P ++ LK L++L + NN ++ +P ++ L L+
Sbjct: 339 DLTPLAFQLIYLNLSFNDLHYFPTEILCLKNLQILKLRNNPIKEIPSEIQQLEFLRIFTI 398
Query: 458 SNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYGMSELYVIE-LNLSQNEIS 306
+ N + P + L L+ LD+S+N++T IP + +L +E L + NE+S
Sbjct: 399 AFNLITVLPIGLFSLSYLEELDVSYNELTFIPNEIQKLRSLEKLTVDGNELS 450
Score = 42.3 bits (95), Expect = 0.002
Identities = 34/123 (27%), Positives = 59/123 (47%), Gaps = 1/123 (0%)
Frame = -2
Query: 536 LNISNNFVQTLPVCLKNLNNLKQVYASNNKLQAFPKQILGLQSLDVLDLSHNKITEIPYG 357
LN+ F+ P L + S N L FP +IL L++L +L L +N I EIP
Sbjct: 327 LNLKGFFILNCPDLTPLAFQLIYLNLSFNDLHYFPTEILCLKNLQILKLRNNPIKEIPSE 386
Query: 356 MSELYVIEL-NLSQNEISLIGEDLHQAPRLKILRLDENCLSLDEIKPSLLRDSKIHTVSV 180
+ +L + + ++ N I+++ L L+ L + N L+ I + + + ++V
Sbjct: 387 IQQLEFLRIFTIAFNLITVLPIGLFSLSYLEELDVSYNELTF--IPNEIQKLRSLEKLTV 444
Query: 179 DGN 171
DGN
Sbjct: 445 DGN 447
>AY899850-1|AAX85198.1| 724|Homo sapiens LGR7.10 protein.
Length = 724
Score = 58.0 bits (134), Expect = 3e-08
Identities = 46/151 (30%), Positives = 78/151 (51%), Gaps = 5/151 (3%)
Frame = -2
Query: 608 QLNLDSNKLQALPESLINLKKLEVLNISNNFVQTLPV-CLKNLNNLKQVYASNNKLQAFP 432
+L+ D L+A+P N+ +++ N ++ LP C KN ++L+++Y NNK+ +
Sbjct: 77 ELDCDETNLRAVPSVSSNVT---AMSLQWNLIRKLPPDCFKNYHDLQKLYLQNNKITSIS 133
Query: 431 -KQILGLQSLDVLDLSHNKITEIPYGMSE-LYVIE-LNLSQNEISLIG-EDLHQAPRLKI 264
GL SL L LSHN+IT + G+ E L+ +E L + N +S I + L +
Sbjct: 134 IYAFRGLNSLTKLYLSHNRITFLKPGVFEDLHRLEWLIIEDNHLSRISPPTFYGLNSLIL 193
Query: 263 LRLDENCLSLDEIKPSLLRDSKIHTVSVDGN 171
L L N L+ KP ++H + ++GN
Sbjct: 194 LVLMNNVLTRLPDKPLCQHMPRLHWLDLEGN 224
Score = 40.7 bits (91), Expect = 0.005
Identities = 47/159 (29%), Positives = 70/159 (44%), Gaps = 8/159 (5%)
Frame = -2
Query: 704 VFSLCDVLRNLDLSKNKLS-VLPDDLSKLKHLKQLNLDSNKLQALPESLI--NLKKLEVL 534
VF L L + N LS + P L L L L +N L LP+ + ++ +L L
Sbjct: 160 VFEDLHRLEWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWL 219
Query: 533 NISNNFVQTLP-VCLKNLNNLKQVYASNNKLQAFPKQILG-LQSLDVLDLSHNKITEI-P 363
++ N + L + + +NL + NK+ + LQ LD LDL NKI + P
Sbjct: 220 DLEGNHIHNLRNLTFISCSNLTVLVMRKNKINHLNENTFAPLQKLDELDLGSNKIENLPP 279
Query: 362 YGMSELYVI-ELNLSQNEISLI-GEDLHQAPRLKILRLD 252
+L + +LNLS N I I +LK L L+
Sbjct: 280 LIFKDLKELSQLNLSYNPIQKIQANQFDYLVKLKSLSLE 318
Score = 39.1 bits (87), Expect = 0.016
Identities = 30/94 (31%), Positives = 45/94 (47%), Gaps = 5/94 (5%)
Frame = -2
Query: 728 KLKEIPIDVFSLCDVLRNLDLSKNKLSVLPDDLSK-LKHLKQLNLDSNKLQALP----ES 564
K+ + + F+ L LDL NK+ LP + K LK L QLNL N +Q + +
Sbjct: 249 KINHLNENTFAPLQKLDELDLGSNKIENLPPLIFKDLKELSQLNLSYNPIQKIQANQFDY 308
Query: 563 LINLKKLEVLNISNNFVQTLPVCLKNLNNLKQVY 462
L+ LK L + I + +Q + L NL +Y
Sbjct: 309 LVKLKSLSLEGIEISNIQQR--MFRPLMNLSHIY 340
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 90,121,969
Number of Sequences: 237096
Number of extensions: 1738812
Number of successful extensions: 7015
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 3995
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5692
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8847149012
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
- SilkBase 1999-2023 -