Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P10_pT_G13
(639 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X05344-1|CAA28955.1| 412|Homo sapiens cathepsin D protein. 183 5e-46
M63138-1|AAA51922.1| 412|Homo sapiens cathepsin D protein. 183 5e-46
M11233-1|AAB59529.1| 412|Homo sapiens CTSD protein. 183 5e-46
CR456947-1|CAG33228.1| 412|Homo sapiens CTSD protein. 183 5e-46
BT020155-1|AAV38957.1| 412|Homo sapiens cathepsin D (lysosomal ... 183 5e-46
BT006910-1|AAP35556.1| 412|Homo sapiens cathepsin D (lysosomal ... 183 5e-46
BC016320-1|AAH16320.1| 412|Homo sapiens cathepsin D protein. 183 5e-46
BC017842-1|AAH17842.1| 420|Homo sapiens napsin A aspartic pepti... 181 2e-45
AF200345-1|AAF17081.1| 420|Homo sapiens aspartyl protease 4 pro... 181 2e-45
AF098484-1|AAD13215.1| 420|Homo sapiens napsin 1 precursor prot... 181 2e-45
AF090386-1|AAD04917.1| 420|Homo sapiens napsin A protein. 181 2e-45
BC111705-1|AAI11706.1| 464|Homo sapiens NAPSB protein protein. 174 3e-43
AF200344-1|AAF17080.1| 450|Homo sapiens aspartyl protease 3 pro... 174 3e-43
M84424-1|AAA52300.1| 396|Homo sapiens cathepsin E protein. 153 7e-37
J05036-1|AAA52130.1| 396|Homo sapiens CTSE protein. 153 7e-37
BX571818-4|CAH73264.1| 396|Homo sapiens cathepsin E protein. 153 7e-37
BC042537-1|AAH42537.1| 396|Homo sapiens cathepsin E protein. 153 7e-37
AJ250717-1|CAB82850.1| 396|Homo sapiens procathepsin E protein. 153 7e-37
X00063-1|CAA24937.1| 300|Homo sapiens protein ( Human kidney mR... 135 1e-31
BC029055-1|AAH29055.1| 388|Homo sapiens pepsinogen 5, group I (... 135 1e-31
M10152-1|AAD03461.1| 406|Homo sapiens renin protein. 134 2e-31
L00073-1|AAA60363.1| 406|Homo sapiens renin protein. 134 2e-31
CR536498-1|CAG38737.1| 406|Homo sapiens REN protein. 134 2e-31
BC047752-1|AAH47752.1| 406|Homo sapiens renin protein. 134 2e-31
BC033474-1|AAH33474.1| 406|Homo sapiens renin protein. 134 2e-31
AL592146-1|CAI16594.1| 406|Homo sapiens renin protein. 134 2e-31
AL592114-1|CAH71224.1| 406|Homo sapiens renin protein. 134 2e-31
J00287-1|AAA98529.1| 388|Homo sapiens PEP protein. 134 3e-31
AY436324-1|AAR03502.1| 403|Homo sapiens renin protein. 134 3e-31
M26901-1|AAA60364.1| 403|Homo sapiens renin protein. 132 1e-30
M26032-1|AAA60061.1| 388|Homo sapiens pepsinogen A protein. 132 1e-30
U75272-1|AAB18273.1| 388|Homo sapiens gastricsin protein. 117 4e-26
M23077-1|AAA60063.1| 388|Homo sapiens pepsinogen C protein. 117 4e-26
M18667-1|AAA60062.1| 385|Homo sapiens pepsinogen protein. 117 4e-26
J04443-1|AAA60074.1| 388|Homo sapiens pepsinogen protein. 117 4e-26
BC073740-1|AAH73740.1| 388|Homo sapiens progastricsin (pepsinog... 117 4e-26
AL365205-1|CAI13181.1| 388|Homo sapiens progastricsin (pepsinog... 117 4e-26
AF188276-1|AAF35835.1| 468|Homo sapiens aspartyl protease protein. 36 0.12
BC015008-1|AAH15008.1| 203|Homo sapiens HAGHL protein protein. 35 0.28
BC014453-1|AAH14453.1| 518|Homo sapiens beta-site APP-cleaving ... 34 0.49
AY358927-1|AAQ89286.1| 518|Homo sapiens BACE2 protein. 34 0.49
AL163285-1|CAB90554.1| 415|Homo sapiens beta-site APP-cleaving ... 34 0.49
AK075539-1|BAC11682.1| 423|Homo sapiens protein ( Homo sapiens ... 34 0.49
AF212252-1|AAG41783.1| 439|Homo sapiens CDA13 protein. 34 0.49
AF204944-1|AAF26368.1| 518|Homo sapiens transmembrane aspartic ... 34 0.49
AF200342-1|AAF17078.1| 518|Homo sapiens aspartyl protease 1 pro... 34 0.49
AF200192-1|AAF13714.1| 518|Homo sapiens memapsin 1 protein. 34 0.49
AF188277-1|AAF35836.1| 396|Homo sapiens aspartyl protease protein. 34 0.49
AF178532-1|AAF29494.1| 518|Homo sapiens aspartyl protease protein. 34 0.49
AF117892-1|AAD45240.1| 518|Homo sapiens aspartic-like protease ... 34 0.49
AF050171-1|AAD45963.1| 518|Homo sapiens aspartyl protease protein. 34 0.49
AK125511-1|BAC86188.1| 559|Homo sapiens rome) (ELN). protein. 31 2.6
U94332-1|AAB53709.1| 401|Homo sapiens osteoprotegerin protein. 31 3.4
BX571818-5|CAH73265.1| 363|Homo sapiens cathepsin E protein. 31 3.4
BC030155-1|AAH30155.1| 401|Homo sapiens tumor necrosis factor r... 31 3.4
AY466112-1|AAR23265.1| 401|Homo sapiens tumor necrosis factor r... 31 3.4
AK223155-1|BAD96875.1| 401|Homo sapiens osteoprotegerin precurs... 31 3.4
AJ250716-1|CAB82849.1| 363|Homo sapiens cathepsin E, alternativ... 31 3.4
AF134187-1|AAF20168.1| 372|Homo sapiens osteoprotegerin protein. 31 3.4
AB008822-1|BAA32076.1| 401|Homo sapiens osteoclastogenesis inhi... 31 3.4
AB002146-1|BAA25910.1| 401|Homo sapiens osteoclastogenesis inhi... 31 3.4
Z97652-2|CAM26431.1| 1269|Homo sapiens Crm, cramped-like (Drosop... 30 8.0
U52840-1|AAC09473.1| 1074|Homo sapiens semaphorin F homolog prot... 30 8.0
BC146661-1|AAI46662.1| 686|Homo sapiens STIM2 protein protein. 30 8.0
BC115696-1|AAI15697.1| 1074|Homo sapiens sema domain, seven thro... 30 8.0
AL031708-1|CAM26357.1| 1269|Homo sapiens Crm, cramped-like (Dros... 30 8.0
AL031009-1|CAM26477.1| 1269|Homo sapiens Crm, cramped-like (Dros... 30 8.0
AK129507-1|BAC85170.1| 122|Homo sapiens protein ( Homo sapiens ... 30 8.0
AE006639-2|AAK61288.1| 1587|Homo sapiens unknown protein. 30 8.0
AB040915-1|BAA96006.1| 818|Homo sapiens KIAA1482 protein protein. 30 8.0
AB037847-1|BAA92664.2| 1066|Homo sapiens KIAA1426 protein protein. 30 8.0
>X05344-1|CAA28955.1| 412|Homo sapiens cathepsin D protein.
Length = 412
Score = 183 bits (445), Expect = 5e-46
Identities = 82/177 (46%), Positives = 110/177 (62%), Gaps = 1/177 (0%)
Frame = -1
Query: 639 SXYLNRDPGATTXXXXXXXGSDPAHYRGDLVRVPLLRDTYWEFHMDSVNVNAS-RFCAQG 463
S YL+RDP A G+D +Y+G L + + R YW+ H+D V V + C +G
Sbjct: 230 SFYLSRDPDAQPGGELMLGGTDSKYYKGSLSYLNVTRKAYWQVHLDQVEVASGLTLCKEG 289
Query: 462 CSAIADTGTSLIAGPSKEVEALNAAVGATAIAFGQYVVDCSLIPHLPRVTFTIAGNDFTL 283
C AI DTGTSL+ GP EV L A+GA + G+Y++ C + LP +T + G + L
Sbjct: 290 CEAIVDTGTSLMVGPVDEVRELQKAIGAVPLIQGEYMIPCEKVSTLPAITLKLGGKGYKL 349
Query: 282 EGNDYVLRVAQFGHTVCLSGFMALDVPKPMGPLWILGDVFIGKYYTEFDAGNRQLGF 112
DY L+V+Q G T+CLSGFM +D+P P GPLWILGDVFIG+YYT FD N ++GF
Sbjct: 350 SPEDYTLKVSQAGKTLCLSGFMGMDIPPPSGPLWILGDVFIGRYYTVFDRDNNRVGF 406
>M63138-1|AAA51922.1| 412|Homo sapiens cathepsin D protein.
Length = 412
Score = 183 bits (445), Expect = 5e-46
Identities = 82/177 (46%), Positives = 110/177 (62%), Gaps = 1/177 (0%)
Frame = -1
Query: 639 SXYLNRDPGATTXXXXXXXGSDPAHYRGDLVRVPLLRDTYWEFHMDSVNVNAS-RFCAQG 463
S YL+RDP A G+D +Y+G L + + R YW+ H+D V V + C +G
Sbjct: 230 SFYLSRDPDAQPGGELMLGGTDSKYYKGSLSYLNVTRKAYWQVHLDQVEVASGLTLCKEG 289
Query: 462 CSAIADTGTSLIAGPSKEVEALNAAVGATAIAFGQYVVDCSLIPHLPRVTFTIAGNDFTL 283
C AI DTGTSL+ GP EV L A+GA + G+Y++ C + LP +T + G + L
Sbjct: 290 CEAIVDTGTSLMVGPVDEVRELQKAIGAVPLIQGEYMIPCEKVSTLPAITLKLGGKGYKL 349
Query: 282 EGNDYVLRVAQFGHTVCLSGFMALDVPKPMGPLWILGDVFIGKYYTEFDAGNRQLGF 112
DY L+V+Q G T+CLSGFM +D+P P GPLWILGDVFIG+YYT FD N ++GF
Sbjct: 350 SPEDYTLKVSQAGKTLCLSGFMGMDIPPPSGPLWILGDVFIGRYYTVFDRDNNRVGF 406
>M11233-1|AAB59529.1| 412|Homo sapiens CTSD protein.
Length = 412
Score = 183 bits (445), Expect = 5e-46
Identities = 82/177 (46%), Positives = 110/177 (62%), Gaps = 1/177 (0%)
Frame = -1
Query: 639 SXYLNRDPGATTXXXXXXXGSDPAHYRGDLVRVPLLRDTYWEFHMDSVNVNAS-RFCAQG 463
S YL+RDP A G+D +Y+G L + + R YW+ H+D V V + C +G
Sbjct: 230 SFYLSRDPDAQPGGELMLGGTDSKYYKGSLSYLNVTRKAYWQVHLDQVEVASGLTLCKEG 289
Query: 462 CSAIADTGTSLIAGPSKEVEALNAAVGATAIAFGQYVVDCSLIPHLPRVTFTIAGNDFTL 283
C AI DTGTSL+ GP EV L A+GA + G+Y++ C + LP +T + G + L
Sbjct: 290 CEAIVDTGTSLMVGPVDEVRELQKAIGAVPLIQGEYMIPCEKVSTLPAITLKLGGKGYKL 349
Query: 282 EGNDYVLRVAQFGHTVCLSGFMALDVPKPMGPLWILGDVFIGKYYTEFDAGNRQLGF 112
DY L+V+Q G T+CLSGFM +D+P P GPLWILGDVFIG+YYT FD N ++GF
Sbjct: 350 SPEDYTLKVSQAGKTLCLSGFMGMDIPPPSGPLWILGDVFIGRYYTVFDRDNNRVGF 406
>CR456947-1|CAG33228.1| 412|Homo sapiens CTSD protein.
Length = 412
Score = 183 bits (445), Expect = 5e-46
Identities = 82/177 (46%), Positives = 110/177 (62%), Gaps = 1/177 (0%)
Frame = -1
Query: 639 SXYLNRDPGATTXXXXXXXGSDPAHYRGDLVRVPLLRDTYWEFHMDSVNVNAS-RFCAQG 463
S YL+RDP A G+D +Y+G L + + R YW+ H+D V V + C +G
Sbjct: 230 SFYLSRDPDAQPGGELMLGGTDSKYYKGSLSYLNVTRKAYWQVHLDQVEVASGLTLCKEG 289
Query: 462 CSAIADTGTSLIAGPSKEVEALNAAVGATAIAFGQYVVDCSLIPHLPRVTFTIAGNDFTL 283
C AI DTGTSL+ GP EV L A+GA + G+Y++ C + LP +T + G + L
Sbjct: 290 CEAIVDTGTSLMVGPVDEVRELQKAIGAVPLIQGEYMIPCEKVSTLPAITLKLGGKGYKL 349
Query: 282 EGNDYVLRVAQFGHTVCLSGFMALDVPKPMGPLWILGDVFIGKYYTEFDAGNRQLGF 112
DY L+V+Q G T+CLSGFM +D+P P GPLWILGDVFIG+YYT FD N ++GF
Sbjct: 350 SPEDYTLKVSQAGKTLCLSGFMGMDIPPPSGPLWILGDVFIGRYYTVFDRDNNRVGF 406
>BT020155-1|AAV38957.1| 412|Homo sapiens cathepsin D (lysosomal
aspartyl protease) protein.
Length = 412
Score = 183 bits (445), Expect = 5e-46
Identities = 82/177 (46%), Positives = 110/177 (62%), Gaps = 1/177 (0%)
Frame = -1
Query: 639 SXYLNRDPGATTXXXXXXXGSDPAHYRGDLVRVPLLRDTYWEFHMDSVNVNAS-RFCAQG 463
S YL+RDP A G+D +Y+G L + + R YW+ H+D V V + C +G
Sbjct: 230 SFYLSRDPDAQPGGELMLGGTDSKYYKGSLSYLNVTRKAYWQVHLDQVEVASGLTLCKEG 289
Query: 462 CSAIADTGTSLIAGPSKEVEALNAAVGATAIAFGQYVVDCSLIPHLPRVTFTIAGNDFTL 283
C AI DTGTSL+ GP EV L A+GA + G+Y++ C + LP +T + G + L
Sbjct: 290 CEAIVDTGTSLMVGPVDEVRELQKAIGAVPLIQGEYMIPCEKVSTLPAITLKLGGKGYKL 349
Query: 282 EGNDYVLRVAQFGHTVCLSGFMALDVPKPMGPLWILGDVFIGKYYTEFDAGNRQLGF 112
DY L+V+Q G T+CLSGFM +D+P P GPLWILGDVFIG+YYT FD N ++GF
Sbjct: 350 SPEDYTLKVSQAGKTLCLSGFMGMDIPPPSGPLWILGDVFIGRYYTVFDRDNNRVGF 406
>BT006910-1|AAP35556.1| 412|Homo sapiens cathepsin D (lysosomal
aspartyl protease) protein.
Length = 412
Score = 183 bits (445), Expect = 5e-46
Identities = 82/177 (46%), Positives = 110/177 (62%), Gaps = 1/177 (0%)
Frame = -1
Query: 639 SXYLNRDPGATTXXXXXXXGSDPAHYRGDLVRVPLLRDTYWEFHMDSVNVNAS-RFCAQG 463
S YL+RDP A G+D +Y+G L + + R YW+ H+D V V + C +G
Sbjct: 230 SFYLSRDPDAQPGGELMLGGTDSKYYKGSLSYLNVTRKAYWQVHLDQVEVASGLTLCKEG 289
Query: 462 CSAIADTGTSLIAGPSKEVEALNAAVGATAIAFGQYVVDCSLIPHLPRVTFTIAGNDFTL 283
C AI DTGTSL+ GP EV L A+GA + G+Y++ C + LP +T + G + L
Sbjct: 290 CEAIVDTGTSLMVGPVDEVRELQKAIGAVPLIQGEYMIPCEKVSTLPAITLKLGGKGYKL 349
Query: 282 EGNDYVLRVAQFGHTVCLSGFMALDVPKPMGPLWILGDVFIGKYYTEFDAGNRQLGF 112
DY L+V+Q G T+CLSGFM +D+P P GPLWILGDVFIG+YYT FD N ++GF
Sbjct: 350 SPEDYTLKVSQAGKTLCLSGFMGMDIPPPSGPLWILGDVFIGRYYTVFDRDNNRVGF 406
>BC016320-1|AAH16320.1| 412|Homo sapiens cathepsin D protein.
Length = 412
Score = 183 bits (445), Expect = 5e-46
Identities = 82/177 (46%), Positives = 110/177 (62%), Gaps = 1/177 (0%)
Frame = -1
Query: 639 SXYLNRDPGATTXXXXXXXGSDPAHYRGDLVRVPLLRDTYWEFHMDSVNVNAS-RFCAQG 463
S YL+RDP A G+D +Y+G L + + R YW+ H+D V V + C +G
Sbjct: 230 SFYLSRDPDAQPGGELMLGGTDSKYYKGSLSYLNVTRKAYWQVHLDQVEVASGLTLCKEG 289
Query: 462 CSAIADTGTSLIAGPSKEVEALNAAVGATAIAFGQYVVDCSLIPHLPRVTFTIAGNDFTL 283
C AI DTGTSL+ GP EV L A+GA + G+Y++ C + LP +T + G + L
Sbjct: 290 CEAIVDTGTSLMVGPVDEVRELQKAIGAVPLIQGEYMIPCEKVSTLPAITLKLGGKGYKL 349
Query: 282 EGNDYVLRVAQFGHTVCLSGFMALDVPKPMGPLWILGDVFIGKYYTEFDAGNRQLGF 112
DY L+V+Q G T+CLSGFM +D+P P GPLWILGDVFIG+YYT FD N ++GF
Sbjct: 350 SPEDYTLKVSQAGKTLCLSGFMGMDIPPPSGPLWILGDVFIGRYYTVFDRDNNRVGF 406
>BC017842-1|AAH17842.1| 420|Homo sapiens napsin A aspartic
peptidase protein.
Length = 420
Score = 181 bits (440), Expect = 2e-45
Identities = 86/172 (50%), Positives = 109/172 (63%), Gaps = 1/172 (0%)
Frame = -1
Query: 639 SXYLNRDPGATTXXXXXXXGSDPAHYRGDLVRVPLLRDTYWEFHMDSVNVNAS-RFCAQG 463
S YLNRDP GSDPAHY L VP+ YW+ HM+ V V CA+G
Sbjct: 218 SFYLNRDPEEPDGGELVLGGSDPAHYIPPLTFVPVTVPAYWQIHMERVKVGPGLTLCAKG 277
Query: 462 CSAIADTGTSLIAGPSKEVEALNAAVGATAIAFGQYVVDCSLIPHLPRVTFTIAGNDFTL 283
C+AI DTGTSLI GP++E+ AL+AA+G + G+Y++ CS IP LP V+F + G F L
Sbjct: 278 CAAILDTGTSLITGPTEEIRALHAAIGGIPLLAGEYIILCSEIPKLPAVSFLLGGVWFNL 337
Query: 282 EGNDYVLRVAQFGHTVCLSGFMALDVPKPMGPLWILGDVFIGKYYTEFDAGN 127
+DYV++ + G +CLSGF ALDVP P GP WILGDVF+G Y FD G+
Sbjct: 338 TAHDYVIQTTRNGVRLCLSGFQALDVPPPAGPFWILGDVFLGTYVAVFDRGD 389
>AF200345-1|AAF17081.1| 420|Homo sapiens aspartyl protease 4
protein.
Length = 420
Score = 181 bits (440), Expect = 2e-45
Identities = 86/172 (50%), Positives = 109/172 (63%), Gaps = 1/172 (0%)
Frame = -1
Query: 639 SXYLNRDPGATTXXXXXXXGSDPAHYRGDLVRVPLLRDTYWEFHMDSVNVNAS-RFCAQG 463
S YLNRDP GSDPAHY L VP+ YW+ HM+ V V CA+G
Sbjct: 218 SFYLNRDPEEPDGGELVLGGSDPAHYIPPLTFVPVTVPAYWQIHMERVKVGPGLTLCAKG 277
Query: 462 CSAIADTGTSLIAGPSKEVEALNAAVGATAIAFGQYVVDCSLIPHLPRVTFTIAGNDFTL 283
C+AI DTGTSLI GP++E+ AL+AA+G + G+Y++ CS IP LP V+F + G F L
Sbjct: 278 CAAILDTGTSLITGPTEEIRALHAAIGGIPLLAGEYIILCSEIPKLPAVSFLLGGVWFNL 337
Query: 282 EGNDYVLRVAQFGHTVCLSGFMALDVPKPMGPLWILGDVFIGKYYTEFDAGN 127
+DYV++ + G +CLSGF ALDVP P GP WILGDVF+G Y FD G+
Sbjct: 338 TAHDYVIQTTRNGVRLCLSGFQALDVPPPAGPFWILGDVFLGTYVAVFDRGD 389
>AF098484-1|AAD13215.1| 420|Homo sapiens napsin 1 precursor
protein.
Length = 420
Score = 181 bits (440), Expect = 2e-45
Identities = 86/172 (50%), Positives = 109/172 (63%), Gaps = 1/172 (0%)
Frame = -1
Query: 639 SXYLNRDPGATTXXXXXXXGSDPAHYRGDLVRVPLLRDTYWEFHMDSVNVNAS-RFCAQG 463
S YLNRDP GSDPAHY L VP+ YW+ HM+ V V CA+G
Sbjct: 218 SFYLNRDPEEPDGGELVLGGSDPAHYIPPLTFVPVTVPAYWQIHMERVKVGPGLTLCAKG 277
Query: 462 CSAIADTGTSLIAGPSKEVEALNAAVGATAIAFGQYVVDCSLIPHLPRVTFTIAGNDFTL 283
C+AI DTGTSLI GP++E+ AL+AA+G + G+Y++ CS IP LP V+F + G F L
Sbjct: 278 CAAILDTGTSLITGPTEEIRALHAAIGGIPLLAGEYIILCSEIPKLPAVSFLLGGVWFNL 337
Query: 282 EGNDYVLRVAQFGHTVCLSGFMALDVPKPMGPLWILGDVFIGKYYTEFDAGN 127
+DYV++ + G +CLSGF ALDVP P GP WILGDVF+G Y FD G+
Sbjct: 338 TAHDYVIQTTRNGVRLCLSGFQALDVPPPAGPFWILGDVFLGTYVAVFDRGD 389
>AF090386-1|AAD04917.1| 420|Homo sapiens napsin A protein.
Length = 420
Score = 181 bits (440), Expect = 2e-45
Identities = 86/172 (50%), Positives = 109/172 (63%), Gaps = 1/172 (0%)
Frame = -1
Query: 639 SXYLNRDPGATTXXXXXXXGSDPAHYRGDLVRVPLLRDTYWEFHMDSVNVNAS-RFCAQG 463
S YLNRDP GSDPAHY L VP+ YW+ HM+ V V CA+G
Sbjct: 218 SFYLNRDPEEPDGGELVLGGSDPAHYIPPLTFVPVTVPAYWQIHMERVKVGPGLTLCAKG 277
Query: 462 CSAIADTGTSLIAGPSKEVEALNAAVGATAIAFGQYVVDCSLIPHLPRVTFTIAGNDFTL 283
C+AI DTGTSLI GP++E+ AL+AA+G + G+Y++ CS IP LP V+F + G F L
Sbjct: 278 CAAILDTGTSLITGPTEEIRALHAAIGGIPLLAGEYIILCSEIPKLPAVSFLLGGVWFNL 337
Query: 282 EGNDYVLRVAQFGHTVCLSGFMALDVPKPMGPLWILGDVFIGKYYTEFDAGN 127
+DYV++ + G +CLSGF ALDVP P GP WILGDVF+G Y FD G+
Sbjct: 338 TAHDYVIQTTRNGVRLCLSGFQALDVPPPAGPFWILGDVFLGTYVAVFDRGD 389
>BC111705-1|AAI11706.1| 464|Homo sapiens NAPSB protein protein.
Length = 464
Score = 174 bits (423), Expect = 3e-43
Identities = 84/176 (47%), Positives = 108/176 (61%), Gaps = 1/176 (0%)
Frame = -1
Query: 639 SXYLNRDPGATTXXXXXXXGSDPAHYRGDLVRVPLLRDTYWEFHMDSVNVNAS-RFCAQG 463
S Y NRDP GSDPAHY L VP+ YW+ HM+ V V + CAQG
Sbjct: 214 SFYFNRDPEVADGGELVLGGSDPAHYIPPLTFVPVTVPAYWQIHMERVKVGSRLTLCAQG 273
Query: 462 CSAIADTGTSLIAGPSKEVEALNAAVGATAIAFGQYVVDCSLIPHLPRVTFTIAGNDFTL 283
C+AI DTGT +I GP++E+ AL+AA+G + G+Y++ CS IP LP V+ I G F L
Sbjct: 274 CAAILDTGTPVIVGPTEEIRALHAAIGGIPLLAGEYIIRCSEIPKLPAVSLLIGGVWFNL 333
Query: 282 EGNDYVLRVAQFGHTVCLSGFMALDVPKPMGPLWILGDVFIGKYYTEFDAGNRQLG 115
DYV++ AQ +CLSGF ALD+ P P+WILGDVF+G Y T FD G+ + G
Sbjct: 334 TAQDYVIQFAQGDVRLCLSGFRALDIASPPVPVWILGDVFLGAYVTVFDRGDMKSG 389
>AF200344-1|AAF17080.1| 450|Homo sapiens aspartyl protease 3
protein.
Length = 450
Score = 174 bits (423), Expect = 3e-43
Identities = 84/176 (47%), Positives = 108/176 (61%), Gaps = 1/176 (0%)
Frame = -1
Query: 639 SXYLNRDPGATTXXXXXXXGSDPAHYRGDLVRVPLLRDTYWEFHMDSVNVNAS-RFCAQG 463
S Y NRDP GSDPAHY L VP+ YW+ HM+ V V + CAQG
Sbjct: 218 SFYFNRDPEVADGGELVLGGSDPAHYIPPLTFVPVTVPAYWQIHMERVKVGSRLTLCAQG 277
Query: 462 CSAIADTGTSLIAGPSKEVEALNAAVGATAIAFGQYVVDCSLIPHLPRVTFTIAGNDFTL 283
C+AI DTGT +I GP++E+ AL+AA+G + G+Y++ CS IP LP V+ I G F L
Sbjct: 278 CAAILDTGTPVIVGPTEEIRALHAAIGGIPLLAGEYIIRCSEIPKLPAVSLLIGGVWFNL 337
Query: 282 EGNDYVLRVAQFGHTVCLSGFMALDVPKPMGPLWILGDVFIGKYYTEFDAGNRQLG 115
DYV++ AQ +CLSGF ALD+ P P+WILGDVF+G Y T FD G+ + G
Sbjct: 338 TAQDYVIQFAQGDVRLCLSGFRALDIASPPVPVWILGDVFLGAYVTVFDRGDMKSG 393
>M84424-1|AAA52300.1| 396|Homo sapiens cathepsin E protein.
Length = 396
Score = 153 bits (370), Expect = 7e-37
Identities = 74/176 (42%), Positives = 105/176 (59%), Gaps = 1/176 (0%)
Frame = -1
Query: 639 SXYLNRDPGATTXXXXXXXGSDPAHYRGDLVRVPLLRDTYWEFHMDSVNVNAS-RFCAQG 463
S Y++ +P G D +H+ G L VP+ + YW+ +D++ V + FC++G
Sbjct: 216 SVYMSSNPEGGAGSELIFGGYDHSHFSGSLNWVPVTKQAYWQIALDNIQVGGTVMFCSEG 275
Query: 462 CSAIADTGTSLIAGPSKEVEALNAAVGATAIAFGQYVVDCSLIPHLPRVTFTIAGNDFTL 283
C AI DTGTSLI GPS +++ L A+GA + G+Y V+C+ + +P VTFTI G +TL
Sbjct: 276 CQAIVDTGTSLITGPSDKIKQLQNAIGAAPVD-GEYAVECANLNVMPDVTFTINGVPYTL 334
Query: 282 EGNDYVLRVAQFGHTVCLSGFMALDVPKPMGPLWILGDVFIGKYYTEFDAGNRQLG 115
Y L G C SGF LD+ P GPLWILGDVFI ++Y+ FD GN ++G
Sbjct: 335 SPTAYTLLDFVDGMQFCSSGFQGLDIHPPAGPLWILGDVFIRQFYSVFDRGNNRVG 390
>J05036-1|AAA52130.1| 396|Homo sapiens CTSE protein.
Length = 396
Score = 153 bits (370), Expect = 7e-37
Identities = 74/176 (42%), Positives = 105/176 (59%), Gaps = 1/176 (0%)
Frame = -1
Query: 639 SXYLNRDPGATTXXXXXXXGSDPAHYRGDLVRVPLLRDTYWEFHMDSVNVNAS-RFCAQG 463
S Y++ +P G D +H+ G L VP+ + YW+ +D++ V + FC++G
Sbjct: 216 SVYMSSNPEGGAGSELIFGGYDHSHFSGSLNWVPVTKQAYWQIALDNIQVGGTVMFCSEG 275
Query: 462 CSAIADTGTSLIAGPSKEVEALNAAVGATAIAFGQYVVDCSLIPHLPRVTFTIAGNDFTL 283
C AI DTGTSLI GPS +++ L A+GA + G+Y V+C+ + +P VTFTI G +TL
Sbjct: 276 CQAIVDTGTSLITGPSDKIKQLQNAIGAAPVD-GEYAVECANLNVMPDVTFTINGVPYTL 334
Query: 282 EGNDYVLRVAQFGHTVCLSGFMALDVPKPMGPLWILGDVFIGKYYTEFDAGNRQLG 115
Y L G C SGF LD+ P GPLWILGDVFI ++Y+ FD GN ++G
Sbjct: 335 SPTAYTLLDFVDGMQFCSSGFQGLDIHPPAGPLWILGDVFIRQFYSVFDRGNNRVG 390
>BX571818-4|CAH73264.1| 396|Homo sapiens cathepsin E protein.
Length = 396
Score = 153 bits (370), Expect = 7e-37
Identities = 74/176 (42%), Positives = 105/176 (59%), Gaps = 1/176 (0%)
Frame = -1
Query: 639 SXYLNRDPGATTXXXXXXXGSDPAHYRGDLVRVPLLRDTYWEFHMDSVNVNAS-RFCAQG 463
S Y++ +P G D +H+ G L VP+ + YW+ +D++ V + FC++G
Sbjct: 216 SVYMSSNPEGGAGSELIFGGYDHSHFSGSLNWVPVTKQAYWQIALDNIQVGGTVMFCSEG 275
Query: 462 CSAIADTGTSLIAGPSKEVEALNAAVGATAIAFGQYVVDCSLIPHLPRVTFTIAGNDFTL 283
C AI DTGTSLI GPS +++ L A+GA + G+Y V+C+ + +P VTFTI G +TL
Sbjct: 276 CQAIVDTGTSLITGPSDKIKQLQNAIGAAPVD-GEYAVECANLNVMPDVTFTINGVPYTL 334
Query: 282 EGNDYVLRVAQFGHTVCLSGFMALDVPKPMGPLWILGDVFIGKYYTEFDAGNRQLG 115
Y L G C SGF LD+ P GPLWILGDVFI ++Y+ FD GN ++G
Sbjct: 335 SPTAYTLLDFVDGMQFCSSGFQGLDIHPPAGPLWILGDVFIRQFYSVFDRGNNRVG 390
>BC042537-1|AAH42537.1| 396|Homo sapiens cathepsin E protein.
Length = 396
Score = 153 bits (370), Expect = 7e-37
Identities = 74/176 (42%), Positives = 105/176 (59%), Gaps = 1/176 (0%)
Frame = -1
Query: 639 SXYLNRDPGATTXXXXXXXGSDPAHYRGDLVRVPLLRDTYWEFHMDSVNVNAS-RFCAQG 463
S Y++ +P G D +H+ G L VP+ + YW+ +D++ V + FC++G
Sbjct: 216 SVYMSSNPEGGAGSELIFGGYDHSHFSGSLNWVPVTKQAYWQIALDNIQVGGTVMFCSEG 275
Query: 462 CSAIADTGTSLIAGPSKEVEALNAAVGATAIAFGQYVVDCSLIPHLPRVTFTIAGNDFTL 283
C AI DTGTSLI GPS +++ L A+GA + G+Y V+C+ + +P VTFTI G +TL
Sbjct: 276 CQAIVDTGTSLITGPSDKIKQLQNAIGAAPVD-GEYAVECANLNVMPDVTFTINGVPYTL 334
Query: 282 EGNDYVLRVAQFGHTVCLSGFMALDVPKPMGPLWILGDVFIGKYYTEFDAGNRQLG 115
Y L G C SGF LD+ P GPLWILGDVFI ++Y+ FD GN ++G
Sbjct: 335 SPTAYTLLDFVDGMQFCSSGFQGLDIHPPAGPLWILGDVFIRQFYSVFDRGNNRVG 390
>AJ250717-1|CAB82850.1| 396|Homo sapiens procathepsin E protein.
Length = 396
Score = 153 bits (370), Expect = 7e-37
Identities = 74/176 (42%), Positives = 105/176 (59%), Gaps = 1/176 (0%)
Frame = -1
Query: 639 SXYLNRDPGATTXXXXXXXGSDPAHYRGDLVRVPLLRDTYWEFHMDSVNVNAS-RFCAQG 463
S Y++ +P G D +H+ G L VP+ + YW+ +D++ V + FC++G
Sbjct: 216 SVYMSSNPEGGAGSELIFGGYDHSHFSGSLNWVPVTKQAYWQIALDNIQVGGTVMFCSEG 275
Query: 462 CSAIADTGTSLIAGPSKEVEALNAAVGATAIAFGQYVVDCSLIPHLPRVTFTIAGNDFTL 283
C AI DTGTSLI GPS +++ L A+GA + G+Y V+C+ + +P VTFTI G +TL
Sbjct: 276 CQAIVDTGTSLITGPSDKIKQLQNAIGAAPVD-GEYAVECANLNVMPDVTFTINGVPYTL 334
Query: 282 EGNDYVLRVAQFGHTVCLSGFMALDVPKPMGPLWILGDVFIGKYYTEFDAGNRQLG 115
Y L G C SGF LD+ P GPLWILGDVFI ++Y+ FD GN ++G
Sbjct: 335 SPTAYTLLDFVDGMQFCSSGFQGLDIHPPAGPLWILGDVFIRQFYSVFDRGNNRVG 390
>X00063-1|CAA24937.1| 300|Homo sapiens protein ( Human kidney mRNA
fragment for renin (aa 105-401). ).
Length = 300
Score = 135 bits (326), Expect = 1e-31
Identities = 67/179 (37%), Positives = 95/179 (53%), Gaps = 3/179 (1%)
Frame = -1
Query: 639 SXYLNRDP--GATTXXXXXXXGSDPAHYRGDLVRVPLLRDTYWEFHMDSVNVNASRF-CA 469
S Y NRD + GSDP HY G+ + L++ W+ M V+V +S C
Sbjct: 118 SFYYNRDSENSQSLGGQIVLGGSDPQHYEGNFHYINLIKTGVWQIQMKGVSVGSSTLLCE 177
Query: 468 QGCSAIADTGTSLIAGPSKEVEALNAAVGATAIAFGQYVVDCSLIPHLPRVTFTIAGNDF 289
GC A+ DTG S I+G + +E L A+GA YVV C+ P LP ++F + G ++
Sbjct: 178 DGCLALVDTGASYISGSTSSIEKLMEALGAKEKRLFDYVVKCNEGPTLPDISFHLGGKEY 237
Query: 288 TLEGNDYVLRVAQFGHTVCLSGFMALDVPKPMGPLWILGDVFIGKYYTEFDAGNRQLGF 112
TL DY+ + + +C A+D+P P GP W LG FI K+YTEFD N ++GF
Sbjct: 238 TLTSADYIFQESYSSKKLCTLAIHAMDIPPPTGPTWALGATFIRKFYTEFDRRNNRIGF 296
>BC029055-1|AAH29055.1| 388|Homo sapiens pepsinogen 5, group I
(pepsinogen A) protein.
Length = 388
Score = 135 bits (326), Expect = 1e-31
Identities = 64/155 (41%), Positives = 93/155 (60%), Gaps = 1/155 (0%)
Frame = -1
Query: 576 DPAHYRGDLVRVPLLRDTYWEFHMDSVNVNASRF-CAQGCSAIADTGTSLIAGPSKEVEA 400
D ++Y G L VP+ + YW+ +DS+ +N CA+GC AI DTGTSL+ GP+ +
Sbjct: 233 DSSYYTGSLNWVPVTVEGYWQITVDSITMNGETIACAEGCQAIVDTGTSLLTGPTSPIAN 292
Query: 399 LNAAVGATAIAFGQYVVDCSLIPHLPRVTFTIAGNDFTLEGNDYVLRVAQFGHTVCLSGF 220
+ + +GA+ + G VV CS I LP + FTI G + + + Y+L+ C+SGF
Sbjct: 293 IQSDIGASENSDGDMVVSCSAISSLPDIVFTINGVQYPVPPSAYILQ----SEGSCISGF 348
Query: 219 MALDVPKPMGPLWILGDVFIGKYYTEFDAGNRQLG 115
++VP G LWILGDVFI +Y+T FD N Q+G
Sbjct: 349 QGMNVPTESGELWILGDVFIRQYFTVFDRANNQVG 383
>M10152-1|AAD03461.1| 406|Homo sapiens renin protein.
Length = 406
Score = 134 bits (325), Expect = 2e-31
Identities = 69/179 (38%), Positives = 96/179 (53%), Gaps = 3/179 (1%)
Frame = -1
Query: 639 SXYLNRDP--GATTXXXXXXXGSDPAHYRGDLVRVPLLRDTYWEFHMDSVNVNASRF-CA 469
S Y NRD + GSDP HY G+ + L++ W+ M V+V +S C
Sbjct: 225 SFYYNRDSENSQSLGGQIVLGGSDPQHYEGNFHYINLIKTGVWQIQMKGVSVGSSTLLCE 284
Query: 468 QGCSAIADTGTSLIAGPSKEVEALNAAVGATAIAFGQYVVDCSLIPHLPRVTFTIAGNDF 289
GC A+ DTG S I+G + +E L A+GA F YVV C+ P LP ++F + G ++
Sbjct: 285 DGCLALVDTGASYISGSTSSIEKLMEALGAKKRLF-DYVVKCNEGPTLPDISFHLGGKEY 343
Query: 288 TLEGNDYVLRVAQFGHTVCLSGFMALDVPKPMGPLWILGDVFIGKYYTEFDAGNRQLGF 112
TL DYV + + +C A+D+P P GP W LG FI K+YTEFD N ++GF
Sbjct: 344 TLTSADYVFQESYSSKKLCTLAIHAMDIPPPTGPTWALGATFIRKFYTEFDRRNNRIGF 402
>L00073-1|AAA60363.1| 406|Homo sapiens renin protein.
Length = 406
Score = 134 bits (325), Expect = 2e-31
Identities = 69/179 (38%), Positives = 96/179 (53%), Gaps = 3/179 (1%)
Frame = -1
Query: 639 SXYLNRDP--GATTXXXXXXXGSDPAHYRGDLVRVPLLRDTYWEFHMDSVNVNASRF-CA 469
S Y NRD + GSDP HY G+ + L++ W+ M V+V +S C
Sbjct: 225 SFYYNRDSENSQSLGGQIVLGGSDPQHYEGNFHYINLIKTGVWQIQMKGVSVGSSTLLCE 284
Query: 468 QGCSAIADTGTSLIAGPSKEVEALNAAVGATAIAFGQYVVDCSLIPHLPRVTFTIAGNDF 289
GC A+ DTG S I+G + +E L A+GA F YVV C+ P LP ++F + G ++
Sbjct: 285 DGCLALVDTGASYISGSTSSIEKLMEALGAKKRLF-DYVVKCNEGPTLPDISFHLGGKEY 343
Query: 288 TLEGNDYVLRVAQFGHTVCLSGFMALDVPKPMGPLWILGDVFIGKYYTEFDAGNRQLGF 112
TL DYV + + +C A+D+P P GP W LG FI K+YTEFD N ++GF
Sbjct: 344 TLTSADYVFQESYSSKKLCTLAIHAMDIPPPTGPTWALGATFIRKFYTEFDRRNNRIGF 402
>CR536498-1|CAG38737.1| 406|Homo sapiens REN protein.
Length = 406
Score = 134 bits (325), Expect = 2e-31
Identities = 69/179 (38%), Positives = 96/179 (53%), Gaps = 3/179 (1%)
Frame = -1
Query: 639 SXYLNRDP--GATTXXXXXXXGSDPAHYRGDLVRVPLLRDTYWEFHMDSVNVNASRF-CA 469
S Y NRD + GSDP HY G+ + L++ W+ M V+V +S C
Sbjct: 225 SFYYNRDSENSQSLGGQIVLGGSDPQHYEGNFHYINLIKTGVWQIQMKGVSVGSSTLLCE 284
Query: 468 QGCSAIADTGTSLIAGPSKEVEALNAAVGATAIAFGQYVVDCSLIPHLPRVTFTIAGNDF 289
GC A+ DTG S I+G + +E L A+GA F YVV C+ P LP ++F + G ++
Sbjct: 285 DGCLALVDTGASYISGSTSSIEKLMEALGAKKRLF-DYVVKCNEGPTLPDISFHLGGKEY 343
Query: 288 TLEGNDYVLRVAQFGHTVCLSGFMALDVPKPMGPLWILGDVFIGKYYTEFDAGNRQLGF 112
TL DYV + + +C A+D+P P GP W LG FI K+YTEFD N ++GF
Sbjct: 344 TLTSADYVFQESYSSKKLCTLAIHAMDIPPPTGPTWALGATFIRKFYTEFDRRNNRIGF 402
>BC047752-1|AAH47752.1| 406|Homo sapiens renin protein.
Length = 406
Score = 134 bits (325), Expect = 2e-31
Identities = 69/179 (38%), Positives = 96/179 (53%), Gaps = 3/179 (1%)
Frame = -1
Query: 639 SXYLNRDP--GATTXXXXXXXGSDPAHYRGDLVRVPLLRDTYWEFHMDSVNVNASRF-CA 469
S Y NRD + GSDP HY G+ + L++ W+ M V+V +S C
Sbjct: 225 SFYYNRDSENSQSLGGQIVLGGSDPQHYEGNFHYINLIKTGVWQIQMKGVSVGSSTLLCE 284
Query: 468 QGCSAIADTGTSLIAGPSKEVEALNAAVGATAIAFGQYVVDCSLIPHLPRVTFTIAGNDF 289
GC A+ DTG S I+G + +E L A+GA F YVV C+ P LP ++F + G ++
Sbjct: 285 DGCLALVDTGASYISGSTSSIEKLMEALGAKKRLF-DYVVKCNEGPTLPDISFHLGGKEY 343
Query: 288 TLEGNDYVLRVAQFGHTVCLSGFMALDVPKPMGPLWILGDVFIGKYYTEFDAGNRQLGF 112
TL DYV + + +C A+D+P P GP W LG FI K+YTEFD N ++GF
Sbjct: 344 TLTSADYVFQESYSSKKLCTLAIHAMDIPPPTGPTWALGATFIRKFYTEFDRRNNRIGF 402
>BC033474-1|AAH33474.1| 406|Homo sapiens renin protein.
Length = 406
Score = 134 bits (325), Expect = 2e-31
Identities = 69/179 (38%), Positives = 96/179 (53%), Gaps = 3/179 (1%)
Frame = -1
Query: 639 SXYLNRDP--GATTXXXXXXXGSDPAHYRGDLVRVPLLRDTYWEFHMDSVNVNASRF-CA 469
S Y NRD + GSDP HY G+ + L++ W+ M V+V +S C
Sbjct: 225 SFYYNRDSENSQSLGGQIVLGGSDPQHYEGNFHYINLIKTGVWQIQMKGVSVGSSTLLCE 284
Query: 468 QGCSAIADTGTSLIAGPSKEVEALNAAVGATAIAFGQYVVDCSLIPHLPRVTFTIAGNDF 289
GC A+ DTG S I+G + +E L A+GA F YVV C+ P LP ++F + G ++
Sbjct: 285 DGCLALVDTGASYISGSTSSIEKLMEALGAKKRLF-DYVVKCNEGPTLPDISFHLGGKEY 343
Query: 288 TLEGNDYVLRVAQFGHTVCLSGFMALDVPKPMGPLWILGDVFIGKYYTEFDAGNRQLGF 112
TL DYV + + +C A+D+P P GP W LG FI K+YTEFD N ++GF
Sbjct: 344 TLTSADYVFQESYSSKKLCTLAIHAMDIPPPTGPTWALGATFIRKFYTEFDRRNNRIGF 402
>AL592146-1|CAI16594.1| 406|Homo sapiens renin protein.
Length = 406
Score = 134 bits (325), Expect = 2e-31
Identities = 69/179 (38%), Positives = 96/179 (53%), Gaps = 3/179 (1%)
Frame = -1
Query: 639 SXYLNRDP--GATTXXXXXXXGSDPAHYRGDLVRVPLLRDTYWEFHMDSVNVNASRF-CA 469
S Y NRD + GSDP HY G+ + L++ W+ M V+V +S C
Sbjct: 225 SFYYNRDSENSQSLGGQIVLGGSDPQHYEGNFHYINLIKTGVWQIQMKGVSVGSSTLLCE 284
Query: 468 QGCSAIADTGTSLIAGPSKEVEALNAAVGATAIAFGQYVVDCSLIPHLPRVTFTIAGNDF 289
GC A+ DTG S I+G + +E L A+GA F YVV C+ P LP ++F + G ++
Sbjct: 285 DGCLALVDTGASYISGSTSSIEKLMEALGAKKRLF-DYVVKCNEGPTLPDISFHLGGKEY 343
Query: 288 TLEGNDYVLRVAQFGHTVCLSGFMALDVPKPMGPLWILGDVFIGKYYTEFDAGNRQLGF 112
TL DYV + + +C A+D+P P GP W LG FI K+YTEFD N ++GF
Sbjct: 344 TLTSADYVFQESYSSKKLCTLAIHAMDIPPPTGPTWALGATFIRKFYTEFDRRNNRIGF 402
>AL592114-1|CAH71224.1| 406|Homo sapiens renin protein.
Length = 406
Score = 134 bits (325), Expect = 2e-31
Identities = 69/179 (38%), Positives = 96/179 (53%), Gaps = 3/179 (1%)
Frame = -1
Query: 639 SXYLNRDP--GATTXXXXXXXGSDPAHYRGDLVRVPLLRDTYWEFHMDSVNVNASRF-CA 469
S Y NRD + GSDP HY G+ + L++ W+ M V+V +S C
Sbjct: 225 SFYYNRDSENSQSLGGQIVLGGSDPQHYEGNFHYINLIKTGVWQIQMKGVSVGSSTLLCE 284
Query: 468 QGCSAIADTGTSLIAGPSKEVEALNAAVGATAIAFGQYVVDCSLIPHLPRVTFTIAGNDF 289
GC A+ DTG S I+G + +E L A+GA F YVV C+ P LP ++F + G ++
Sbjct: 285 DGCLALVDTGASYISGSTSSIEKLMEALGAKKRLF-DYVVKCNEGPTLPDISFHLGGKEY 343
Query: 288 TLEGNDYVLRVAQFGHTVCLSGFMALDVPKPMGPLWILGDVFIGKYYTEFDAGNRQLGF 112
TL DYV + + +C A+D+P P GP W LG FI K+YTEFD N ++GF
Sbjct: 344 TLTSADYVFQESYSSKKLCTLAIHAMDIPPPTGPTWALGATFIRKFYTEFDRRNNRIGF 402
>J00287-1|AAA98529.1| 388|Homo sapiens PEP protein.
Length = 388
Score = 134 bits (323), Expect = 3e-31
Identities = 63/155 (40%), Positives = 93/155 (60%), Gaps = 1/155 (0%)
Frame = -1
Query: 576 DPAHYRGDLVRVPLLRDTYWEFHMDSVNVNASRF-CAQGCSAIADTGTSLIAGPSKEVEA 400
D ++Y G L VP+ + YW+ +DS+ +N CA+GC AI DTGTSL+ GP+ +
Sbjct: 233 DSSYYTGSLNWVPVTVEGYWQITVDSITMNGEAIACAEGCQAIVDTGTSLLTGPTSPIAN 292
Query: 399 LNAAVGATAIAFGQYVVDCSLIPHLPRVTFTIAGNDFTLEGNDYVLRVAQFGHTVCLSGF 220
+ + +GA+ + G VV CS I LP + FTI G + + + Y+L+ C+SGF
Sbjct: 293 IQSDIGASENSDGDMVVSCSAISSLPDIVFTINGVQYPVPPSAYILQ----SEGSCISGF 348
Query: 219 MALDVPKPMGPLWILGDVFIGKYYTEFDAGNRQLG 115
+++P G LWILGDVFI +Y+T FD N Q+G
Sbjct: 349 QGMNLPTESGELWILGDVFIRQYFTVFDRANNQVG 383
>AY436324-1|AAR03502.1| 403|Homo sapiens renin protein.
Length = 403
Score = 134 bits (323), Expect = 3e-31
Identities = 68/177 (38%), Positives = 96/177 (54%), Gaps = 1/177 (0%)
Frame = -1
Query: 639 SXYLNRDPGATTXXXXXXXGSDPAHYRGDLVRVPLLRDTYWEFHMDSVNVNASRF-CAQG 463
S Y NR+ + GSDP HY G+ + L++ W+ M V+V +S C G
Sbjct: 225 SFYYNRN-SQSLGGQIVLGGSDPQHYEGNFHYINLIKTGVWQIQMKGVSVGSSTLLCEDG 283
Query: 462 CSAIADTGTSLIAGPSKEVEALNAAVGATAIAFGQYVVDCSLIPHLPRVTFTIAGNDFTL 283
C A+ DTG S I+G + +E L A+GA F YVV C+ P LP ++F + G ++TL
Sbjct: 284 CLALVDTGASYISGSTSSIEKLMEALGAKKRLF-DYVVKCNEGPTLPDISFHLGGKEYTL 342
Query: 282 EGNDYVLRVAQFGHTVCLSGFMALDVPKPMGPLWILGDVFIGKYYTEFDAGNRQLGF 112
DYV + + +C A+D+P P GP W LG FI K+YTEFD N ++GF
Sbjct: 343 TSADYVFQESYSSKKLCTLAIHAMDIPPPTGPTWALGATFIRKFYTEFDRRNNRIGF 399
>M26901-1|AAA60364.1| 403|Homo sapiens renin protein.
Length = 403
Score = 132 bits (319), Expect = 1e-30
Identities = 68/177 (38%), Positives = 96/177 (54%), Gaps = 1/177 (0%)
Frame = -1
Query: 639 SXYLNRDPGATTXXXXXXXGSDPAHYRGDLVRVPLLRDTYWEFHMDSVNVNASRF-CAQG 463
S Y NR+ + GSDP HY G+ + L++ W+ M V+V +S C G
Sbjct: 225 SFYYNRN-SQSLGGQIVLGGSDPQHYEGNFHYINLIKTGVWQIQMKGVSVGSSTLLCEDG 283
Query: 462 CSAIADTGTSLIAGPSKEVEALNAAVGATAIAFGQYVVDCSLIPHLPRVTFTIAGNDFTL 283
C A+ DTG S I+G + +E L A+GA F YVV C+ P LP ++F + G ++TL
Sbjct: 284 CLALVDTGASYISGSTSCIEKLMEALGAKKRLF-DYVVKCNEGPTLPDISFHLGGKEYTL 342
Query: 282 EGNDYVLRVAQFGHTVCLSGFMALDVPKPMGPLWILGDVFIGKYYTEFDAGNRQLGF 112
DYV + + +C A+D+P P GP W LG FI K+YTEFD N ++GF
Sbjct: 343 TSADYVFQESYSSKKLCTLAIHAMDIPPPTGPTWALGATFIRKFYTEFDRRNNRIGF 399
>M26032-1|AAA60061.1| 388|Homo sapiens pepsinogen A protein.
Length = 388
Score = 132 bits (319), Expect = 1e-30
Identities = 62/155 (40%), Positives = 93/155 (60%), Gaps = 1/155 (0%)
Frame = -1
Query: 576 DPAHYRGDLVRVPLLRDTYWEFHMDSVNVNASRF-CAQGCSAIADTGTSLIAGPSKEVEA 400
D ++Y G L VP+ + YW+ +DS+ +N CA+GC AI DTGTSL+ GP+ +
Sbjct: 233 DSSYYTGSLNWVPVTVEGYWQITVDSITMNGEAIACAEGCQAIVDTGTSLLTGPTSPIAN 292
Query: 399 LNAAVGATAIAFGQYVVDCSLIPHLPRVTFTIAGNDFTLEGNDYVLRVAQFGHTVCLSGF 220
+ + +GA+ + G VV CS I LP + FTI G + + + Y+L+ C+SGF
Sbjct: 293 IQSDIGASENSDGDMVVSCSAISSLPDIVFTINGVQYPVPPSAYILQ----SEGSCISGF 348
Query: 219 MALDVPKPMGPLWILGDVFIGKYYTEFDAGNRQLG 115
+++P G LWILGDVFI +Y+T F+ N Q+G
Sbjct: 349 QGMNLPTESGELWILGDVFIRQYFTVFERANNQVG 383
>U75272-1|AAB18273.1| 388|Homo sapiens gastricsin protein.
Length = 388
Score = 117 bits (281), Expect = 4e-26
Identities = 63/179 (35%), Positives = 98/179 (54%), Gaps = 3/179 (1%)
Frame = -1
Query: 639 SXYLNRDPGATTXXXXXXXGSDPAHYRGDLVRVPLLRDTYWEFHMDS--VNVNASRFCAQ 466
S YL+ G++ D + Y G + P+ ++ YW+ ++ + AS +C++
Sbjct: 211 SVYLSNQQGSSGGAVVFGGV-DSSLYTGQIYWAPVTQELYWQIGIEEFLIGGQASGWCSE 269
Query: 465 GCSAIADTGTSLIAGPSKEVEALNAAVGATAIAFGQYVVDCSLIPHLPRVTFTIAGNDFT 286
GC AI DTGTSL+ P + + AL A GA +GQ++V+C+ I +LP +TF I G +F
Sbjct: 270 GCQAIVDTGTSLLTVPQQYMSALLQATGAQEDEYGQFLVNCNSIQNLPSLTFIINGVEFP 329
Query: 285 LEGNDYVLRVAQFGHTVCLSGFMALDVPKPMG-PLWILGDVFIGKYYTEFDAGNRQLGF 112
L + Y+L + C G + G PLWILGDVF+ YY+ +D GN ++GF
Sbjct: 330 LPPSSYILS----NNGYCTVGVEPTYLSSQNGQPLWILGDVFLRSYYSVYDLGNNRVGF 384
>M23077-1|AAA60063.1| 388|Homo sapiens pepsinogen C protein.
Length = 388
Score = 117 bits (281), Expect = 4e-26
Identities = 63/179 (35%), Positives = 98/179 (54%), Gaps = 3/179 (1%)
Frame = -1
Query: 639 SXYLNRDPGATTXXXXXXXGSDPAHYRGDLVRVPLLRDTYWEFHMDS--VNVNASRFCAQ 466
S YL+ G++ D + Y G + P+ ++ YW+ ++ + AS +C++
Sbjct: 211 SVYLSNQQGSSGGAVVFGGV-DSSLYTGQIYWAPVTQELYWQIGIEEFLIGGQASGWCSE 269
Query: 465 GCSAIADTGTSLIAGPSKEVEALNAAVGATAIAFGQYVVDCSLIPHLPRVTFTIAGNDFT 286
GC AI DTGTSL+ P + + AL A GA +GQ++V+C+ I +LP +TF I G +F
Sbjct: 270 GCQAIVDTGTSLLTVPQQYMSALLQATGAQEDEYGQFLVNCNSIQNLPSLTFIINGVEFP 329
Query: 285 LEGNDYVLRVAQFGHTVCLSGFMALDVPKPMG-PLWILGDVFIGKYYTEFDAGNRQLGF 112
L + Y+L + C G + G PLWILGDVF+ YY+ +D GN ++GF
Sbjct: 330 LPPSSYILS----NNGYCTVGVEPTYLSSQNGQPLWILGDVFLRSYYSVYDLGNNRVGF 384
>M18667-1|AAA60062.1| 385|Homo sapiens pepsinogen protein.
Length = 385
Score = 117 bits (281), Expect = 4e-26
Identities = 63/179 (35%), Positives = 98/179 (54%), Gaps = 3/179 (1%)
Frame = -1
Query: 639 SXYLNRDPGATTXXXXXXXGSDPAHYRGDLVRVPLLRDTYWEFHMDS--VNVNASRFCAQ 466
S YL+ G++ D + Y G + P+ ++ YW+ ++ + AS +C++
Sbjct: 208 SVYLSNQQGSSGGAVVFGGV-DSSLYTGQIYWAPVTQELYWQIGIEEFLIGGQASGWCSE 266
Query: 465 GCSAIADTGTSLIAGPSKEVEALNAAVGATAIAFGQYVVDCSLIPHLPRVTFTIAGNDFT 286
GC AI DTGTSL+ P + + AL A GA +GQ++V+C+ I +LP +TF I G +F
Sbjct: 267 GCQAIVDTGTSLLTVPQQYMSALLQATGAQEDEYGQFLVNCNSIQNLPSLTFIINGVEFP 326
Query: 285 LEGNDYVLRVAQFGHTVCLSGFMALDVPKPMG-PLWILGDVFIGKYYTEFDAGNRQLGF 112
L + Y+L + C G + G PLWILGDVF+ YY+ +D GN ++GF
Sbjct: 327 LPPSSYILS----NNGYCTVGVEPTYLSSQNGQPLWILGDVFLRSYYSVYDLGNNRVGF 381
>J04443-1|AAA60074.1| 388|Homo sapiens pepsinogen protein.
Length = 388
Score = 117 bits (281), Expect = 4e-26
Identities = 63/179 (35%), Positives = 98/179 (54%), Gaps = 3/179 (1%)
Frame = -1
Query: 639 SXYLNRDPGATTXXXXXXXGSDPAHYRGDLVRVPLLRDTYWEFHMDS--VNVNASRFCAQ 466
S YL+ G++ D + Y G + P+ ++ YW+ ++ + AS +C++
Sbjct: 211 SVYLSNQQGSSGGAVVFGGV-DSSLYTGQIYWAPVTQELYWQIGIEEFLIGGQASGWCSE 269
Query: 465 GCSAIADTGTSLIAGPSKEVEALNAAVGATAIAFGQYVVDCSLIPHLPRVTFTIAGNDFT 286
GC AI DTGTSL+ P + + AL A GA +GQ++V+C+ I +LP +TF I G +F
Sbjct: 270 GCQAIVDTGTSLLTVPQQYMSALLQATGAQEDEYGQFLVNCNSIQNLPSLTFIINGVEFP 329
Query: 285 LEGNDYVLRVAQFGHTVCLSGFMALDVPKPMG-PLWILGDVFIGKYYTEFDAGNRQLGF 112
L + Y+L + C G + G PLWILGDVF+ YY+ +D GN ++GF
Sbjct: 330 LPPSSYILS----NNGYCTVGVEPTYLSSQNGQPLWILGDVFLRSYYSVYDLGNNRVGF 384
>BC073740-1|AAH73740.1| 388|Homo sapiens progastricsin (pepsinogen
C) protein.
Length = 388
Score = 117 bits (281), Expect = 4e-26
Identities = 63/179 (35%), Positives = 98/179 (54%), Gaps = 3/179 (1%)
Frame = -1
Query: 639 SXYLNRDPGATTXXXXXXXGSDPAHYRGDLVRVPLLRDTYWEFHMDS--VNVNASRFCAQ 466
S YL+ G++ D + Y G + P+ ++ YW+ ++ + AS +C++
Sbjct: 211 SVYLSNQQGSSGGAVVFGGV-DSSLYTGQIYWAPVTQELYWQIGIEEFLIGGQASGWCSE 269
Query: 465 GCSAIADTGTSLIAGPSKEVEALNAAVGATAIAFGQYVVDCSLIPHLPRVTFTIAGNDFT 286
GC AI DTGTSL+ P + + AL A GA +GQ++V+C+ I +LP +TF I G +F
Sbjct: 270 GCQAIVDTGTSLLTVPQQYMSALLQATGAQEDEYGQFLVNCNSIQNLPSLTFIINGVEFP 329
Query: 285 LEGNDYVLRVAQFGHTVCLSGFMALDVPKPMG-PLWILGDVFIGKYYTEFDAGNRQLGF 112
L + Y+L + C G + G PLWILGDVF+ YY+ +D GN ++GF
Sbjct: 330 LPPSSYILS----NNGYCTVGVEPTYLSSQNGQPLWILGDVFLRSYYSVYDLGNNRVGF 384
>AL365205-1|CAI13181.1| 388|Homo sapiens progastricsin (pepsinogen
C) protein.
Length = 388
Score = 117 bits (281), Expect = 4e-26
Identities = 63/179 (35%), Positives = 98/179 (54%), Gaps = 3/179 (1%)
Frame = -1
Query: 639 SXYLNRDPGATTXXXXXXXGSDPAHYRGDLVRVPLLRDTYWEFHMDS--VNVNASRFCAQ 466
S YL+ G++ D + Y G + P+ ++ YW+ ++ + AS +C++
Sbjct: 211 SVYLSNQQGSSGGAVVFGGV-DSSLYTGQIYWAPVTQELYWQIGIEEFLIGGQASGWCSE 269
Query: 465 GCSAIADTGTSLIAGPSKEVEALNAAVGATAIAFGQYVVDCSLIPHLPRVTFTIAGNDFT 286
GC AI DTGTSL+ P + + AL A GA +GQ++V+C+ I +LP +TF I G +F
Sbjct: 270 GCQAIVDTGTSLLTVPQQYMSALLQATGAQEDEYGQFLVNCNSIQNLPSLTFIINGVEFP 329
Query: 285 LEGNDYVLRVAQFGHTVCLSGFMALDVPKPMG-PLWILGDVFIGKYYTEFDAGNRQLGF 112
L + Y+L + C G + G PLWILGDVF+ YY+ +D GN ++GF
Sbjct: 330 LPPSSYILS----NNGYCTVGVEPTYLSSQNGQPLWILGDVFLRSYYSVYDLGNNRVGF 384
>AF188276-1|AAF35835.1| 468|Homo sapiens aspartyl protease protein.
Length = 468
Score = 35.9 bits (79), Expect = 0.12
Identities = 22/87 (25%), Positives = 45/87 (51%), Gaps = 7/87 (8%)
Frame = -1
Query: 576 DPAHYRGDLVRVPLLRDTYWEFHM-------DSVNVNASRFCAQGCSAIADTGTSLIAGP 418
+P+ Y+GD+ P+ + Y++ + S+N++ + A AI D+GT+L+ P
Sbjct: 255 EPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNAD--KAIVDSGTTLLRLP 312
Query: 417 SKEVEALNAAVGATAIAFGQYVVDCSL 337
K +A+ AV ++ + Q ++ L
Sbjct: 313 QKVFDAVVEAVARASLLYIQPMMGAGL 339
>BC015008-1|AAH15008.1| 203|Homo sapiens HAGHL protein protein.
Length = 203
Score = 34.7 bits (76), Expect = 0.28
Identities = 47/132 (35%), Positives = 56/132 (42%), Gaps = 11/132 (8%)
Frame = +1
Query: 100 HGGREPELAVPRVELRVVLADEHVPQDPQR-AHG--LRHVQRHEAGQAHRVPELCHPEHV 270
H PELA R L V+ ADE + +R AHG LR R G+ R P P
Sbjct: 59 HARGNPELARLRPGLAVLGADERIFSLTRRLAHGEELRVSARSREGRGGR-PGSTRPHR- 116
Query: 271 VVALEREVVPGDGKGDSRQVRYEAAVHDVLPEGDGR--GAHRRVEGFHLLGG-----PGD 429
A V G + R H++LP G GR G R V G +GG PG
Sbjct: 117 -SACSSAAVRGHPRALPPDARPHRRPHELLPVG-GRLPGPTRPVLGRRAVGGRLRLVPGG 174
Query: 430 QRRARVGD-GRA 462
QR A V + GRA
Sbjct: 175 QRPADVPEPGRA 186
>BC014453-1|AAH14453.1| 518|Homo sapiens beta-site APP-cleaving
enzyme 2 protein.
Length = 518
Score = 33.9 bits (74), Expect = 0.49
Identities = 20/76 (26%), Positives = 40/76 (52%), Gaps = 7/76 (9%)
Frame = -1
Query: 576 DPAHYRGDLVRVPLLRDTYWEFHM-------DSVNVNASRFCAQGCSAIADTGTSLIAGP 418
+P+ Y+GD+ P+ + Y++ + S+N++ + A AI D+GT+L+ P
Sbjct: 255 EPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNAD--KAIVDSGTTLLRLP 312
Query: 417 SKEVEALNAAVGATAI 370
K +A+ AV ++
Sbjct: 313 QKVFDAVVEAVARASL 328
>AY358927-1|AAQ89286.1| 518|Homo sapiens BACE2 protein.
Length = 518
Score = 33.9 bits (74), Expect = 0.49
Identities = 20/76 (26%), Positives = 40/76 (52%), Gaps = 7/76 (9%)
Frame = -1
Query: 576 DPAHYRGDLVRVPLLRDTYWEFHM-------DSVNVNASRFCAQGCSAIADTGTSLIAGP 418
+P+ Y+GD+ P+ + Y++ + S+N++ + A AI D+GT+L+ P
Sbjct: 255 EPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNAD--KAIVDSGTTLLRLP 312
Query: 417 SKEVEALNAAVGATAI 370
K +A+ AV ++
Sbjct: 313 QKVFDAVVEAVARASL 328
>AL163285-1|CAB90554.1| 415|Homo sapiens beta-site APP-cleaving
enzyme 2, EC 3.4.23. protein.
Length = 415
Score = 33.9 bits (74), Expect = 0.49
Identities = 20/76 (26%), Positives = 40/76 (52%), Gaps = 7/76 (9%)
Frame = -1
Query: 576 DPAHYRGDLVRVPLLRDTYWEFHM-------DSVNVNASRFCAQGCSAIADTGTSLIAGP 418
+P+ Y+GD+ P+ + Y++ + S+N++ + A AI D+GT+L+ P
Sbjct: 152 EPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNAD--KAIVDSGTTLLRLP 209
Query: 417 SKEVEALNAAVGATAI 370
K +A+ AV ++
Sbjct: 210 QKVFDAVVEAVARASL 225
>AK075539-1|BAC11682.1| 423|Homo sapiens protein ( Homo sapiens
cDNA PSEC0239 fis, clone OVARC1000363, highly similar to
Homo sapiens aspartyl protease mRNA. ).
Length = 423
Score = 33.9 bits (74), Expect = 0.49
Identities = 20/76 (26%), Positives = 40/76 (52%), Gaps = 7/76 (9%)
Frame = -1
Query: 576 DPAHYRGDLVRVPLLRDTYWEFHM-------DSVNVNASRFCAQGCSAIADTGTSLIAGP 418
+P+ Y+GD+ P+ + Y++ + S+N++ + A AI D+GT+L+ P
Sbjct: 160 EPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNAD--KAIVDSGTTLLRLP 217
Query: 417 SKEVEALNAAVGATAI 370
K +A+ AV ++
Sbjct: 218 QKVFDAVVEAVARASL 233
>AF212252-1|AAG41783.1| 439|Homo sapiens CDA13 protein.
Length = 439
Score = 33.9 bits (74), Expect = 0.49
Identities = 20/76 (26%), Positives = 40/76 (52%), Gaps = 7/76 (9%)
Frame = -1
Query: 576 DPAHYRGDLVRVPLLRDTYWEFHM-------DSVNVNASRFCAQGCSAIADTGTSLIAGP 418
+P+ Y+GD+ P+ + Y++ + S+N++ + A AI D+GT+L+ P
Sbjct: 176 EPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNAD--KAIVDSGTTLLRLP 233
Query: 417 SKEVEALNAAVGATAI 370
K +A+ AV ++
Sbjct: 234 QKVFDAVVEAVARASL 249
>AF204944-1|AAF26368.1| 518|Homo sapiens transmembrane aspartic
proteinase Asp 1 protein.
Length = 518
Score = 33.9 bits (74), Expect = 0.49
Identities = 20/76 (26%), Positives = 40/76 (52%), Gaps = 7/76 (9%)
Frame = -1
Query: 576 DPAHYRGDLVRVPLLRDTYWEFHM-------DSVNVNASRFCAQGCSAIADTGTSLIAGP 418
+P+ Y+GD+ P+ + Y++ + S+N++ + A AI D+GT+L+ P
Sbjct: 255 EPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNAD--KAIVDSGTTLLRLP 312
Query: 417 SKEVEALNAAVGATAI 370
K +A+ AV ++
Sbjct: 313 QKVFDAVVEAVARASL 328
>AF200342-1|AAF17078.1| 518|Homo sapiens aspartyl protease 1
protein.
Length = 518
Score = 33.9 bits (74), Expect = 0.49
Identities = 20/76 (26%), Positives = 40/76 (52%), Gaps = 7/76 (9%)
Frame = -1
Query: 576 DPAHYRGDLVRVPLLRDTYWEFHM-------DSVNVNASRFCAQGCSAIADTGTSLIAGP 418
+P+ Y+GD+ P+ + Y++ + S+N++ + A AI D+GT+L+ P
Sbjct: 255 EPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNAD--KAIVDSGTTLLRLP 312
Query: 417 SKEVEALNAAVGATAI 370
K +A+ AV ++
Sbjct: 313 QKVFDAVVEAVARASL 328
>AF200192-1|AAF13714.1| 518|Homo sapiens memapsin 1 protein.
Length = 518
Score = 33.9 bits (74), Expect = 0.49
Identities = 20/76 (26%), Positives = 40/76 (52%), Gaps = 7/76 (9%)
Frame = -1
Query: 576 DPAHYRGDLVRVPLLRDTYWEFHM-------DSVNVNASRFCAQGCSAIADTGTSLIAGP 418
+P+ Y+GD+ P+ + Y++ + S+N++ + A AI D+GT+L+ P
Sbjct: 255 EPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNAD--KAIVDSGTTLLRLP 312
Query: 417 SKEVEALNAAVGATAI 370
K +A+ AV ++
Sbjct: 313 QKVFDAVVEAVARASL 328
>AF188277-1|AAF35836.1| 396|Homo sapiens aspartyl protease protein.
Length = 396
Score = 33.9 bits (74), Expect = 0.49
Identities = 20/76 (26%), Positives = 40/76 (52%), Gaps = 7/76 (9%)
Frame = -1
Query: 576 DPAHYRGDLVRVPLLRDTYWEFHM-------DSVNVNASRFCAQGCSAIADTGTSLIAGP 418
+P+ Y+GD+ P+ + Y++ + S+N++ + A AI D+GT+L+ P
Sbjct: 255 EPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNAD--KAIVDSGTTLLRLP 312
Query: 417 SKEVEALNAAVGATAI 370
K +A+ AV ++
Sbjct: 313 QKVFDAVVEAVARASL 328
>AF178532-1|AAF29494.1| 518|Homo sapiens aspartyl protease protein.
Length = 518
Score = 33.9 bits (74), Expect = 0.49
Identities = 20/76 (26%), Positives = 40/76 (52%), Gaps = 7/76 (9%)
Frame = -1
Query: 576 DPAHYRGDLVRVPLLRDTYWEFHM-------DSVNVNASRFCAQGCSAIADTGTSLIAGP 418
+P+ Y+GD+ P+ + Y++ + S+N++ + A AI D+GT+L+ P
Sbjct: 255 EPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNAD--KAIVDSGTTLLRLP 312
Query: 417 SKEVEALNAAVGATAI 370
K +A+ AV ++
Sbjct: 313 QKVFDAVVEAVARASL 328
>AF117892-1|AAD45240.1| 518|Homo sapiens aspartic-like protease
protein.
Length = 518
Score = 33.9 bits (74), Expect = 0.49
Identities = 20/76 (26%), Positives = 40/76 (52%), Gaps = 7/76 (9%)
Frame = -1
Query: 576 DPAHYRGDLVRVPLLRDTYWEFHM-------DSVNVNASRFCAQGCSAIADTGTSLIAGP 418
+P+ Y+GD+ P+ + Y++ + S+N++ + A AI D+GT+L+ P
Sbjct: 255 EPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNAD--KAIVDSGTTLLRLP 312
Query: 417 SKEVEALNAAVGATAI 370
K +A+ AV ++
Sbjct: 313 QKVFDAVVEAVARASL 328
>AF050171-1|AAD45963.1| 518|Homo sapiens aspartyl protease protein.
Length = 518
Score = 33.9 bits (74), Expect = 0.49
Identities = 20/76 (26%), Positives = 40/76 (52%), Gaps = 7/76 (9%)
Frame = -1
Query: 576 DPAHYRGDLVRVPLLRDTYWEFHM-------DSVNVNASRFCAQGCSAIADTGTSLIAGP 418
+P+ Y+GD+ P+ + Y++ + S+N++ + A AI D+GT+L+ P
Sbjct: 255 EPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNAD--KAIVDSGTTLLRLP 312
Query: 417 SKEVEALNAAVGATAI 370
K +A+ AV ++
Sbjct: 313 QKVFDAVVEAVARASL 328
>AK125511-1|BAC86188.1| 559|Homo sapiens rome) (ELN). protein.
Length = 559
Score = 31.5 bits (68), Expect = 2.6
Identities = 13/31 (41%), Positives = 17/31 (54%), Gaps = 3/31 (9%)
Frame = -2
Query: 257 WHNSGTRCACPA-SW--RWTCRSPWARCGSW 174
W G+ C C + SW W+ R W+ CGSW
Sbjct: 457 WSWRGSWCRCGSWSWLGSWSWRGSWSWCGSW 487
>U94332-1|AAB53709.1| 401|Homo sapiens osteoprotegerin protein.
Length = 401
Score = 31.1 bits (67), Expect = 3.4
Identities = 14/34 (41%), Positives = 18/34 (52%)
Frame = +2
Query: 152 YLPMNTSPRIHSGPMGFGTSSAMKPDRHTVCPNC 253
YL + + S P GFG A P+R+TVC C
Sbjct: 112 YLEIEFCLKHRSCPPGFGVVQAGTPERNTVCKRC 145
>BX571818-5|CAH73265.1| 363|Homo sapiens cathepsin E protein.
Length = 363
Score = 31.1 bits (67), Expect = 3.4
Identities = 13/48 (27%), Positives = 24/48 (50%)
Frame = -1
Query: 639 SXYLNRDPGATTXXXXXXXGSDPAHYRGDLVRVPLLRDTYWEFHMDSV 496
S Y++ +P G D +H+ G L VP+ + YW+ +D++
Sbjct: 216 SVYMSSNPEGGAGSELIFGGYDHSHFSGSLNWVPVTKQAYWQIALDNM 263
>BC030155-1|AAH30155.1| 401|Homo sapiens tumor necrosis factor
receptor superfamily, member 11b (osteoprotegerin)
protein.
Length = 401
Score = 31.1 bits (67), Expect = 3.4
Identities = 14/34 (41%), Positives = 18/34 (52%)
Frame = +2
Query: 152 YLPMNTSPRIHSGPMGFGTSSAMKPDRHTVCPNC 253
YL + + S P GFG A P+R+TVC C
Sbjct: 112 YLEIEFCLKHRSCPPGFGVVQAGTPERNTVCKRC 145
>AY466112-1|AAR23265.1| 401|Homo sapiens tumor necrosis factor
receptor superfamily, member 11b (osteoprotegerin)
protein.
Length = 401
Score = 31.1 bits (67), Expect = 3.4
Identities = 14/34 (41%), Positives = 18/34 (52%)
Frame = +2
Query: 152 YLPMNTSPRIHSGPMGFGTSSAMKPDRHTVCPNC 253
YL + + S P GFG A P+R+TVC C
Sbjct: 112 YLEIEFCLKHRSCPPGFGVVQAGTPERNTVCKRC 145
>AK223155-1|BAD96875.1| 401|Homo sapiens osteoprotegerin precursor
variant protein.
Length = 401
Score = 31.1 bits (67), Expect = 3.4
Identities = 14/34 (41%), Positives = 18/34 (52%)
Frame = +2
Query: 152 YLPMNTSPRIHSGPMGFGTSSAMKPDRHTVCPNC 253
YL + + S P GFG A P+R+TVC C
Sbjct: 112 YLEIEFCLKHRSCPPGFGVVQAGTPERNTVCKRC 145
>AJ250716-1|CAB82849.1| 363|Homo sapiens cathepsin E, alternative
protein.
Length = 363
Score = 31.1 bits (67), Expect = 3.4
Identities = 13/48 (27%), Positives = 24/48 (50%)
Frame = -1
Query: 639 SXYLNRDPGATTXXXXXXXGSDPAHYRGDLVRVPLLRDTYWEFHMDSV 496
S Y++ +P G D +H+ G L VP+ + YW+ +D++
Sbjct: 216 SVYMSSNPEGGAGSELIFGGYDHSHFSGSLNWVPVTKQAYWQIALDNM 263
>AF134187-1|AAF20168.1| 372|Homo sapiens osteoprotegerin protein.
Length = 372
Score = 31.1 bits (67), Expect = 3.4
Identities = 14/34 (41%), Positives = 18/34 (52%)
Frame = +2
Query: 152 YLPMNTSPRIHSGPMGFGTSSAMKPDRHTVCPNC 253
YL + + S P GFG A P+R+TVC C
Sbjct: 91 YLEIEFCLKHRSCPPGFGVVQAGTPERNTVCKRC 124
>AB008822-1|BAA32076.1| 401|Homo sapiens osteoclastogenesis
inhibitory factor protein.
Length = 401
Score = 31.1 bits (67), Expect = 3.4
Identities = 14/34 (41%), Positives = 18/34 (52%)
Frame = +2
Query: 152 YLPMNTSPRIHSGPMGFGTSSAMKPDRHTVCPNC 253
YL + + S P GFG A P+R+TVC C
Sbjct: 112 YLEIEFCLKHRSCPPGFGVVQAGTPERNTVCKRC 145
>AB002146-1|BAA25910.1| 401|Homo sapiens osteoclastogenesis
inhibitory factor (OCIF) protein.
Length = 401
Score = 31.1 bits (67), Expect = 3.4
Identities = 14/34 (41%), Positives = 18/34 (52%)
Frame = +2
Query: 152 YLPMNTSPRIHSGPMGFGTSSAMKPDRHTVCPNC 253
YL + + S P GFG A P+R+TVC C
Sbjct: 112 YLEIEFCLKHRSCPPGFGVVQAGTPERNTVCKRC 145
>Z97652-2|CAM26431.1| 1269|Homo sapiens Crm, cramped-like
(Drosophila) protein.
Length = 1269
Score = 29.9 bits (64), Expect = 8.0
Identities = 19/54 (35%), Positives = 23/54 (42%)
Frame = +2
Query: 359 CPKAMAVAPTAALRASTSLEGPAISDVPVSAMAEQPWAQKRLALTLTESMWNSQ 520
C K +A AP L+ S GP S +A + RLA L E WN Q
Sbjct: 628 CTKDLADAPAEELQEKGSPAGPPPSQGQPAARPPKEVPASRLAQQLREEGWNLQ 681
>U52840-1|AAC09473.1| 1074|Homo sapiens semaphorin F homolog
protein.
Length = 1074
Score = 29.9 bits (64), Expect = 8.0
Identities = 10/22 (45%), Positives = 13/22 (59%)
Frame = -2
Query: 230 CPASWRWTCRSPWARCGSWGTC 165
CP W+C SPW +C + TC
Sbjct: 838 CPVDGVWSCWSPWTKCSA--TC 857
>BC146661-1|AAI46662.1| 686|Homo sapiens STIM2 protein protein.
Length = 686
Score = 29.9 bits (64), Expect = 8.0
Identities = 20/55 (36%), Positives = 24/55 (43%), Gaps = 2/55 (3%)
Frame = -3
Query: 331 APAASHLYHRRERLHARGQRLRAP--GGTIRAHGVPVRLHGAGRAEAHGPAVDPG 173
AP S RR R + AP G ++A G P+R H A H PA PG
Sbjct: 20 APGGSPCLRRRGRPEESPAAVVAPRGAGELQAAGAPLRFHPASPRRLH-PASTPG 73
>BC115696-1|AAI15697.1| 1074|Homo sapiens sema domain, seven
thrombospondin repeats (type 1 and type 1-like),
transmembra protein.
Length = 1074
Score = 29.9 bits (64), Expect = 8.0
Identities = 10/22 (45%), Positives = 13/22 (59%)
Frame = -2
Query: 230 CPASWRWTCRSPWARCGSWGTC 165
CP W+C SPW +C + TC
Sbjct: 838 CPVDGVWSCWSPWTKCSA--TC 857
>AL031708-1|CAM26357.1| 1269|Homo sapiens Crm, cramped-like
(Drosophila) protein.
Length = 1269
Score = 29.9 bits (64), Expect = 8.0
Identities = 19/54 (35%), Positives = 23/54 (42%)
Frame = +2
Query: 359 CPKAMAVAPTAALRASTSLEGPAISDVPVSAMAEQPWAQKRLALTLTESMWNSQ 520
C K +A AP L+ S GP S +A + RLA L E WN Q
Sbjct: 628 CTKDLADAPAEELQEKGSPAGPPPSQGQPAARPPKEVPASRLAQQLREEGWNLQ 681
>AL031009-1|CAM26477.1| 1269|Homo sapiens Crm, cramped-like
(Drosophila) protein.
Length = 1269
Score = 29.9 bits (64), Expect = 8.0
Identities = 19/54 (35%), Positives = 23/54 (42%)
Frame = +2
Query: 359 CPKAMAVAPTAALRASTSLEGPAISDVPVSAMAEQPWAQKRLALTLTESMWNSQ 520
C K +A AP L+ S GP S +A + RLA L E WN Q
Sbjct: 628 CTKDLADAPAEELQEKGSPAGPPPSQGQPAARPPKEVPASRLAQQLREEGWNLQ 681
>AK129507-1|BAC85170.1| 122|Homo sapiens protein ( Homo sapiens
cDNA FLJ25996 fis, clone DMC06615. ).
Length = 122
Score = 29.9 bits (64), Expect = 8.0
Identities = 22/78 (28%), Positives = 31/78 (39%), Gaps = 1/78 (1%)
Frame = +2
Query: 68 CLINASGRAAHTAGANPSWRFPASNSV*YL-PMNTSPRIHSGPMGFGTSSAMKPDRHTVC 244
CL + S A T G P ++ P N PR+ P F T +P T C
Sbjct: 21 CLADDSWCAGQTPGQETPPTVPECSAGNQTRPQNRFPRLPPNPANFRTPQGARPRPLTTC 80
Query: 245 PNCATRST*SLPSSVKSF 298
C+ R++ S P + F
Sbjct: 81 -LCSQRASLSCPGPLPPF 97
>AE006639-2|AAK61288.1| 1587|Homo sapiens unknown protein.
Length = 1587
Score = 29.9 bits (64), Expect = 8.0
Identities = 19/54 (35%), Positives = 23/54 (42%)
Frame = +2
Query: 359 CPKAMAVAPTAALRASTSLEGPAISDVPVSAMAEQPWAQKRLALTLTESMWNSQ 520
C K +A AP L+ S GP S +A + RLA L E WN Q
Sbjct: 880 CTKDLADAPAEELQEKGSPAGPPPSQGQPAARPPKEVPASRLAQQLREEGWNLQ 933
>AB040915-1|BAA96006.1| 818|Homo sapiens KIAA1482 protein protein.
Length = 818
Score = 29.9 bits (64), Expect = 8.0
Identities = 20/55 (36%), Positives = 24/55 (43%), Gaps = 2/55 (3%)
Frame = -3
Query: 331 APAASHLYHRRERLHARGQRLRAP--GGTIRAHGVPVRLHGAGRAEAHGPAVDPG 173
AP S RR R + AP G ++A G P+R H A H PA PG
Sbjct: 5 APGGSPCLRRRGRPEESPAAVVAPRGAGELQAAGAPLRFHPASPRRLH-PASTPG 58
>AB037847-1|BAA92664.2| 1066|Homo sapiens KIAA1426 protein protein.
Length = 1066
Score = 29.9 bits (64), Expect = 8.0
Identities = 19/54 (35%), Positives = 23/54 (42%)
Frame = +2
Query: 359 CPKAMAVAPTAALRASTSLEGPAISDVPVSAMAEQPWAQKRLALTLTESMWNSQ 520
C K +A AP L+ S GP S +A + RLA L E WN Q
Sbjct: 425 CTKDLADAPAEELQEKGSPAGPPPSQGQPAARPPKEVPASRLAQQLREEGWNLQ 478
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 91,120,049
Number of Sequences: 237096
Number of extensions: 2017092
Number of successful extensions: 7294
Number of sequences better than 10.0: 71
Number of HSP's better than 10.0 without gapping: 6719
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7225
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 7028963750
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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