Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P10_F_E16
(784 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X52889-1|CAA37068.1| 1934|Homo sapiens cardiac beta myosin heavy... 233 4e-61
X51591-1|CAA35940.1| 1151|Homo sapiens beta-myosin heavy chain (... 233 4e-61
M58018-1|AAA62830.1| 1935|Homo sapiens beta-myosin heavy chain p... 233 4e-61
M57965-1|AAA51837.1| 1935|Homo sapiens beta-myosin heavy chain p... 233 4e-61
EF560725-1|ABQ59035.1| 1934|Homo sapiens MYH7 protein protein. 233 4e-61
EF179180-1|ABN05283.1| 1935|Homo sapiens myosin, heavy chain 7, ... 233 4e-61
BC112173-1|AAI12174.1| 1935|Homo sapiens myosin, heavy chain 7, ... 233 4e-61
BC112171-1|AAI12172.1| 1935|Homo sapiens myosin, heavy chain 7, ... 233 4e-61
AJ238393-1|CAC20413.1| 1935|Homo sapiens beta-myosin heavy chain... 233 4e-61
AB209708-1|BAD92945.1| 1574|Homo sapiens myosin, heavy polypepti... 233 4e-61
AY518538-1|AAT44534.1| 1179|Homo sapiens rhabdomyosarcoma antige... 233 5e-61
Z20656-1|CAA79675.1| 1939|Homo sapiens cardiac alpha-myosin heav... 231 3e-60
BC132667-1|AAI32668.1| 1939|Homo sapiens myosin, heavy chain 6, ... 231 3e-60
AF111783-1|AAD29949.1| 1939|Homo sapiens myosin heavy chain IIb ... 231 3e-60
X15696-1|CAA33731.1| 1085|Homo sapiens protein ( Human muscle mR... 229 7e-60
AY517555-1|AAT44528.1| 941|Homo sapiens hypothetical rhabdomyos... 229 7e-60
X51593-1|CAA35942.1| 1085|Homo sapiens embryonic myosin heavy ch... 228 2e-59
X13988-1|CAA32167.1| 1940|Homo sapiens protein ( Human mRNA for ... 227 3e-59
X13100-1|CAA31492.1| 1167|Homo sapiens myosin heavy chain (1167 ... 227 3e-59
BC126409-1|AAI26410.1| 1941|Homo sapiens myosin, heavy chain 2, ... 225 1e-58
BC114545-1|AAI14546.1| 1939|Homo sapiens myosin, heavy chain 1, ... 225 1e-58
AF111785-1|AAD29951.1| 1939|Homo sapiens myosin heavy chain IIx/... 225 1e-58
AF111784-1|AAD29950.1| 1941|Homo sapiens myosin heavy chain IIa ... 225 1e-58
D00943-1|BAA00791.1| 1939|Homo sapiens cardiac alpha-myosin heav... 225 1e-58
Z38133-1|CAA86293.1| 1937|Homo sapiens Myosin protein. 222 1e-57
M36769-1|AAC17185.1| 1937|Homo sapiens perinatal myosin heavy ch... 219 9e-57
X03740-1|CAA27380.1| 876|Homo sapiens protein ( Human skeletal ... 218 2e-56
AF111782-1|AAD29948.1| 1938|Homo sapiens myosin heavy chain prot... 215 2e-55
AK025690-1|BAB15219.1| 746|Homo sapiens protein ( Homo sapiens ... 211 2e-54
BC151242-1|AAI51243.1| 1983|Homo sapiens myosin, heavy chain 7B,... 210 6e-54
BC007808-1|AAH07808.1| 1006|Homo sapiens MYH7B protein protein. 210 6e-54
AL133324-2|CAI19310.2| 1983|Homo sapiens myosin, heavy chain 7B,... 210 6e-54
AL132825-6|CAI43047.2| 1983|Homo sapiens myosin, heavy chain 7B,... 210 6e-54
AB040945-1|BAA96036.2| 2010|Homo sapiens KIAA1512 protein protein. 210 6e-54
X51592-1|CAA35941.1| 1437|Homo sapiens fetal-myosin heavy chain ... 209 7e-54
AB023217-1|BAA76844.2| 1956|Homo sapiens KIAA1000 protein protein. 164 3e-40
X03741-1|CAA27381.1| 635|Homo sapiens protein ( Human cardiac m... 135 2e-31
X69292-1|CAA49154.1| 881|Homo sapiens smooth muscle mysosin he... 129 1e-29
D10667-1|BAA36971.1| 1052|Homo sapiens smooth muscle myosin heav... 129 1e-29
BC104906-1|AAI04907.1| 1938|Homo sapiens myosin, heavy chain 11,... 129 1e-29
BC101677-1|AAI01678.1| 1938|Homo sapiens myosin, heavy chain 11,... 129 1e-29
AY520817-1|AAS98911.1| 1945|Homo sapiens smooth muscle myosin he... 129 1e-29
AY520816-1|AAS98910.1| 1979|Homo sapiens smooth muscle myosin he... 129 1e-29
AF001548-1|AAC31665.1| 1857|Homo sapiens Myosin heavy chain (MHY... 129 1e-29
AB020673-1|BAA74889.2| 1984|Homo sapiens KIAA0866 protein protein. 129 1e-29
Z82215-4|CAB05105.1| 1960|Homo sapiens myosin, heavy chain 9, no... 128 2e-29
CR456526-1|CAG30412.1| 1960|Homo sapiens MYH9 protein. 128 2e-29
AB191263-1|BAD52439.1| 1960|Homo sapiens non-muscle myosin heavy... 128 2e-29
M69181-1|AAA99177.1| 1976|Homo sapiens non-muscle myosin B protein. 127 5e-29
BC117691-1|AAI17692.1| 1976|Homo sapiens myosin, heavy chain 10,... 127 5e-29
AB210026-1|BAE06108.1| 2018|Homo sapiens MYH10 variant protein p... 127 5e-29
M25139-1|AAA60385.1| 611|Homo sapiens myosin heavy chain beta-s... 126 1e-28
BC117690-1|AAI17691.1| 1976|Homo sapiens myosin, heavy chain 10,... 126 1e-28
M31013-1|AAA36349.1| 1247|Homo sapiens protein ( Human nonmuscle... 121 3e-27
AY165122-1|AAO39147.1| 1995|Homo sapiens myosin heavy chain prot... 120 4e-27
AB111886-1|BAC98374.1| 1571|Homo sapiens KIAA2034 protein protein. 120 4e-27
BC049849-1|AAH49849.1| 1374|Homo sapiens MYH9 protein protein. 99 2e-20
BC022376-1|AAH22376.1| 627|Homo sapiens Unknown (protein for IM... 94 4e-19
BC004396-1|AAH04396.1| 182|Homo sapiens MYH14 protein protein. 81 3e-15
AF020091-1|AAB69327.1| 622|Homo sapiens smooth muscle myosin he... 78 4e-14
AF013570-1|AAB69326.1| 588|Homo sapiens smooth muscle myosin he... 78 4e-14
AL832639-1|CAD89954.1| 1331|Homo sapiens hypothetical protein pr... 77 7e-14
BC000280-1|AAH00280.1| 471|Homo sapiens MYH10 protein protein. 75 4e-13
X06976-1|CAA30039.1| 543|Homo sapiens beta myosin heavy chain (... 74 7e-13
M21665-1|AAA36345.1| 524|Homo sapiens protein ( Human beta-myos... 74 7e-13
M17712-1|AAA36343.1| 543|Homo sapiens protein ( Human cardiac m... 74 7e-13
M25142-1|AAA60387.1| 389|Homo sapiens myosin heavy chain alpha-... 73 1e-12
D86970-1|BAA13206.2| 2067|Homo sapiens KIAA0216 protein. 73 1e-12
AY703984-1|AAV80770.1| 1581|Homo sapiens SP-A receptor subunit S... 73 1e-12
AB177860-1|BAD66838.1| 1715|Homo sapiens KIAA0216 splice variant... 73 1e-12
AB177858-1|BAD66836.1| 2046|Homo sapiens KIAA0216 splice variant... 73 1e-12
M21664-1|AAA36344.1| 532|Homo sapiens protein ( Human alpha-myo... 72 2e-12
BC039612-1|AAH39612.1| 2002|Homo sapiens MYO18A protein protein. 72 2e-12
BC080545-1|AAH80545.1| 498|Homo sapiens MYH11 protein protein. 70 1e-11
S67240-1|AAB28951.1| 330|Homo sapiens smooth muscle myosin heav... 69 3e-11
S67238-1|AAB28950.1| 296|Homo sapiens smooth muscle myosin heav... 67 6e-11
BC129803-1|AAI29804.1| 638|Homo sapiens MYH14 protein protein. 66 1e-10
AK023943-1|BAB14735.1| 545|Homo sapiens protein ( Homo sapiens ... 66 1e-10
AK131080-1|BAC85130.1| 563|Homo sapiens FLJ00279 protein protein. 66 1e-10
S67247-1|AAB28952.1| 226|Homo sapiens smooth muscle myosin heav... 65 2e-10
M81105-1|AAA59888.1| 1337|Homo sapiens cellular myosin heavy cha... 64 4e-10
L12579-1|AAA35654.1| 678|Homo sapiens protein ( Human alternati... 62 2e-09
BC066592-1|AAH66592.1| 1516|Homo sapiens CUTL1 protein protein. 62 2e-09
AK222832-1|BAD96552.1| 678|Homo sapiens CCAAT displacement prot... 62 2e-09
AC005086-1|AAP22331.1| 317|Homo sapiens unknown protein. 62 2e-09
BC000676-1|AAH00676.2| 483|Homo sapiens MYH14 protein protein. 62 2e-09
BC118918-1|AAI18919.1| 1302|Homo sapiens cingulin-like 1 protein. 62 3e-09
BC112049-1|AAI12050.1| 1302|Homo sapiens cingulin-like 1 protein. 62 3e-09
BC093827-1|AAH93827.1| 1302|Homo sapiens cingulin-like 1 protein. 62 3e-09
AY274808-1|AAP42073.1| 1302|Homo sapiens KIAA1749 protein protein. 62 3e-09
AK056673-1|BAB71249.1| 883|Homo sapiens protein ( Homo sapiens ... 62 3e-09
AB051536-1|BAB21840.2| 1047|Homo sapiens KIAA1749 protein protein. 62 3e-09
BC025422-1|AAH25422.1| 676|Homo sapiens cut-like 1, CCAAT displ... 61 4e-09
Y09420-1|CAA70574.1| 400|Homo sapiens huntingtin interacting pr... 60 7e-09
U79734-1|AAC51257.1| 914|Homo sapiens huntingtin interacting pr... 60 7e-09
BC139786-1|AAI39787.1| 517|Homo sapiens HIP1 protein protein. 60 7e-09
BC110545-1|AAI10546.1| 1037|Homo sapiens huntingtin interacting ... 60 7e-09
AF365404-1|AAL87037.1| 1030|Homo sapiens huntingtin-interacting ... 60 7e-09
AF052288-1|AAC33564.1| 995|Homo sapiens huntingtin interacting ... 60 7e-09
X98801-1|CAA67333.1| 1263|Homo sapiens dynactin protein. 60 1e-08
BC071583-1|AAH71583.1| 1139|Homo sapiens DCTN1 protein protein. 60 1e-08
AF086947-1|AAD03694.1| 1261|Homo sapiens dynactin 1 protein. 60 1e-08
AF064205-2|AAD55812.1| 1144|Homo sapiens dynactin 1 p135 isoform... 60 1e-08
AF064205-1|AAD55811.1| 1278|Homo sapiens dynactin 1 p150 isoform... 60 1e-08
AB209625-1|BAD92862.1| 459|Homo sapiens dynactin 1 isoform 1 va... 60 1e-08
D87931-1|BAA75636.1| 1388|Homo sapiens Rho kinase protein. 59 2e-08
BC111801-1|AAI11802.1| 703|Homo sapiens ROCK2 protein protein. 59 2e-08
AC018463-2|AAX93049.1| 1337|Homo sapiens unknown protein. 59 2e-08
AB014519-1|BAA31594.2| 1428|Homo sapiens KIAA0619 protein protein. 59 2e-08
U90236-1|AAC51654.2| 1262|Homo sapiens myosin VI protein. 59 2e-08
BC007877-1|AAH07877.2| 256|Homo sapiens MYH14 protein protein. 59 2e-08
AY610514-1|AAT37906.1| 1302|Homo sapiens paracingulin protein. 59 2e-08
AL365436-3|CAI16590.1| 1203|Homo sapiens cingulin protein. 59 2e-08
AL136093-4|CAI42826.1| 1253|Homo sapiens myosin VI protein. 59 2e-08
AL136093-3|CAI42824.1| 1262|Homo sapiens myosin VI protein. 59 2e-08
AL109897-3|CAI19522.1| 1253|Homo sapiens myosin VI protein. 59 2e-08
AL109897-2|CAI19520.1| 1262|Homo sapiens myosin VI protein. 59 2e-08
AF263462-1|AAF74498.1| 1203|Homo sapiens cingulin protein. 59 2e-08
AB037740-1|BAA92557.1| 1208|Homo sapiens KIAA1319 protein protein. 59 2e-08
X03445-1|CAA27174.1| 572|Homo sapiens protein ( Human mRNA for ... 58 4e-08
X03444-1|CAA27173.1| 702|Homo sapiens protein ( Human mRNA for ... 58 4e-08
M13451-1|AAA36164.1| 572|Homo sapiens protein ( Human lamin C m... 58 4e-08
BT007441-1|AAP36109.1| 600|Homo sapiens lamin B1 protein. 58 4e-08
BC014507-1|AAH14507.1| 664|Homo sapiens lamin A/C protein. 58 4e-08
BC006551-1|AAH06551.1| 600|Homo sapiens lamin B2 protein. 58 4e-08
BC003162-1|AAH03162.1| 572|Homo sapiens lamin A/C protein. 58 4e-08
BC000511-1|AAH00511.1| 572|Homo sapiens lamin A/C protein. 58 4e-08
AY847597-1|AAW32540.1| 664|Homo sapiens lamin A/C transcript va... 58 4e-08
AY847596-1|AAW32539.1| 480|Homo sapiens lamin A/C transcript va... 58 4e-08
AY528714-1|ABB04050.1| 487|Homo sapiens rhabdomyosarcoma antige... 58 4e-08
AY357727-1|AAR29466.1| 614|Homo sapiens progerin protein. 58 4e-08
AL135927-4|CAI15522.1| 664|Homo sapiens lamin A/C protein. 58 4e-08
AL135927-3|CAI15523.1| 614|Homo sapiens lamin A/C protein. 58 4e-08
AL135927-2|CAI15521.1| 572|Homo sapiens lamin A/C protein. 58 4e-08
AL135927-1|CAI15520.1| 465|Homo sapiens lamin A/C protein. 58 4e-08
AK027863-1|BAB55415.1| 612|Homo sapiens protein ( Homo sapiens ... 58 4e-08
X75304-1|CAA53052.1| 3259|Homo sapiens giantin protein. 58 5e-08
M97501-1|AAA35693.1| 1392|Homo sapiens cytoplasmic linker protei... 58 5e-08
D25542-1|BAA05025.1| 3225|Homo sapiens golgi antigen gcp372 prot... 58 5e-08
BC117209-1|AAI17210.1| 1438|Homo sapiens CLIP1 protein protein. 58 5e-08
AY847595-1|AAW32538.1| 664|Homo sapiens lamin A/C transcript va... 58 5e-08
AB209115-1|BAD92352.1| 1065|Homo sapiens restin isoform a varian... 58 5e-08
BC114620-1|AAI14621.1| 1756|Homo sapiens periplakin protein. 57 6e-08
AB011140-1|BAA25494.1| 1426|Homo sapiens KIAA0568 protein protein. 57 6e-08
BX530088-3|CAI95784.1| 810|Homo sapiens GRIP1 associated protei... 57 8e-08
X95654-1|CAA64956.1| 976|Homo sapiens polypeptide of 976 aa pro... 56 1e-07
X64838-1|CAA46050.1| 1427|Homo sapiens restin protein. 56 1e-07
BC126305-1|AAI26306.1| 1438|Homo sapiens CLIP1 protein protein. 56 1e-07
BC126266-1|AAI26267.1| 976|Homo sapiens synaptonemal complex pr... 56 1e-07
BC114213-1|AAI14214.1| 1392|Homo sapiens CAP-GLY domain containi... 56 1e-07
BC033088-1|AAH33088.1| 465|Homo sapiens LMNA protein protein. 56 1e-07
AL645502-1|CAH70064.1| 976|Homo sapiens synaptonemal complex pr... 56 1e-07
AL358372-3|CAH72848.1| 792|Homo sapiens synaptonemal complex pr... 56 1e-07
AL358372-2|CAH72847.1| 976|Homo sapiens synaptonemal complex pr... 56 1e-07
AF273043-1|AAG34903.1| 795|Homo sapiens CTCL tumor antigen se2-... 56 1e-07
AF229111-1|AAK00229.1| 1285|Homo sapiens myosin VI protein. 56 1e-07
U51587-1|AAB81549.1| 767|Homo sapiens Golgi complex autoantigen... 56 1e-07
BC146764-1|AAI46765.1| 1285|Homo sapiens myosin VI protein. 56 1e-07
BC032853-1|AAH32853.1| 767|Homo sapiens golgi autoantigen, golg... 56 1e-07
AL136093-2|CAI42825.1| 1285|Homo sapiens myosin VI protein. 56 1e-07
AL109897-1|CAI19521.1| 1285|Homo sapiens myosin VI protein. 56 1e-07
AF041004-1|AAD17459.1| 1756|Homo sapiens periplakin protein. 56 1e-07
AF013717-1|AAC39668.1| 1756|Homo sapiens periplakin protein. 56 1e-07
AF001691-1|AAC17738.1| 1756|Homo sapiens 195 kDa cornified envel... 56 1e-07
AB208858-1|BAD92095.1| 400|Homo sapiens golgin 97 variant protein. 56 1e-07
AB002387-1|BAA20843.2| 1296|Homo sapiens KIAA0389 protein. 56 1e-07
AY681966-1|AAV87216.1| 2069|Homo sapiens citron protein. 55 3e-07
AY257469-1|AAP13528.1| 2027|Homo sapiens rho/rac-interacting cit... 55 3e-07
AC002563-2|AAB71327.1| 1286|Homo sapiens WUGSC:H_127H14.1 protein. 55 3e-07
AB023166-1|BAA76793.2| 1559|Homo sapiens KIAA0949 protein protein. 55 3e-07
Z54367-1|CAA91196.1| 4684|Homo sapiens plectin protein. 55 3e-07
U63610-1|AAB05428.1| 4574|Homo sapiens plectin protein. 55 3e-07
U53204-1|AAB05427.1| 4574|Homo sapiens plectin protein. 55 3e-07
S73840-1|AAC13916.1| 231|Homo sapiens type IIA myosin heavy cha... 55 3e-07
AY480051-1|AAR95684.1| 4547|Homo sapiens plectin 11 protein. 55 3e-07
AY480050-1|AAR95683.1| 4551|Homo sapiens plectin 10 protein. 55 3e-07
AY480049-1|AAR95682.1| 4547|Homo sapiens plectin 8 protein. 55 3e-07
AY480048-1|AAR95681.1| 4515|Homo sapiens plectin 7 protein. 55 3e-07
AY480047-1|AAR95680.1| 4684|Homo sapiens plectin 6 protein. 55 3e-07
AY480046-1|AAR95679.1| 4525|Homo sapiens plectin 3 protein. 55 3e-07
AY480045-1|AAR95678.1| 4533|Homo sapiens plectin 2 protein. 55 3e-07
AY480044-1|AAR95677.1| 4574|Homo sapiens plectin 1 protein. 55 3e-07
AL121586-7|CAB89415.1| 2442|Homo sapiens centrosomal protein 250... 55 3e-07
AF049105-1|AAC07988.1| 2442|Homo sapiens centrosomal Nek2-associ... 55 3e-07
AF022655-1|AAC06349.1| 2442|Homo sapiens cep250 centrosome assoc... 55 3e-07
M63618-1|AAA35606.1| 2095|Homo sapiens bullous pemphigoid antige... 54 6e-07
L11690-1|AAA52288.1| 2649|Homo sapiens bullous pemphigoid antige... 54 6e-07
BC113114-1|AAI13115.1| 1354|Homo sapiens Rho-associated, coiled-... 54 6e-07
BC034046-1|AAH34046.1| 1202|Homo sapiens protein tyrosine phosph... 54 6e-07
AL096710-6|CAI22047.1| 2649|Homo sapiens dystonin protein. 54 6e-07
U22816-1|AAC50173.1| 1202|Homo sapiens LAR-interacting protein 1... 54 8e-07
U22815-1|AAC50172.1| 1185|Homo sapiens LAR-interacting protein 1... 54 8e-07
DQ355971-1|ABC67469.1| 1711|Homo sapiens CDC42 binding protein k... 54 8e-07
BC047871-1|AAH47871.1| 933|Homo sapiens CDC42BPB protein protein. 54 8e-07
AF128625-1|AAD37506.1| 1711|Homo sapiens CDC42-binding protein k... 54 8e-07
AB032950-1|BAA86438.2| 1760|Homo sapiens KIAA1124 protein protein. 54 8e-07
U43195-1|AAB02814.1| 1354|Homo sapiens Rho-associated, coiled-co... 53 1e-06
U31906-1|AAC51791.1| 2083|Homo sapiens golgin-245 protein. 53 1e-06
BC146657-1|AAI46658.1| 771|Homo sapiens CGN protein protein. 53 1e-06
AY640415-1|AAT68295.1| 284|Homo sapiens tropomyosin alpha stria... 53 1e-06
AB208965-1|BAD92202.1| 705|Homo sapiens Rho-associated, coiled-... 53 1e-06
Y00067-1|CAA68276.1| 916|Homo sapiens NF-M protein. 53 1e-06
EF560737-1|ABQ59047.1| 877|Homo sapiens NEFM protein protein. 53 1e-06
EF560736-1|ABQ59046.1| 916|Homo sapiens NEFM protein protein. 53 1e-06
BC109126-1|AAI09127.1| 872|Homo sapiens chromosome 10 open read... 53 1e-06
BC101517-1|AAI01518.1| 637|Homo sapiens RAB11 family interactin... 53 1e-06
BC096757-1|AAH96757.1| 916|Homo sapiens neurofilament, medium p... 53 1e-06
BC093914-1|AAH93914.1| 637|Homo sapiens RAB11 family interactin... 53 1e-06
BC053545-1|AAH53545.1| 245|Homo sapiens tropomyosin 1 (alpha) p... 53 1e-06
BC050473-1|AAH50473.1| 287|Homo sapiens TPM1 protein protein. 53 1e-06
BC036225-1|AAH36225.1| 872|Homo sapiens chromosome 10 open read... 53 1e-06
AY640414-1|AAT68294.1| 284|Homo sapiens sarcomeric tropomyosin ... 53 1e-06
AY169244-1|AAO21970.1| 637|Homo sapiens rab11-family interactin... 53 1e-06
AL831830-1|CAD38543.1| 296|Homo sapiens hypothetical protein pr... 53 1e-06
AL355378-1|CAI15667.1| 872|Homo sapiens novel protein protein. 53 1e-06
AL162742-5|CAI12110.1| 872|Homo sapiens novel protein protein. 53 1e-06
AK093227-1|BAC04102.1| 550|Homo sapiens protein ( Homo sapiens ... 53 1e-06
AJ314646-1|CAC44535.1| 609|Homo sapiens hypothetical protein pr... 53 1e-06
AB209041-1|BAD92278.1| 303|Homo sapiens TPM1 protein variant pr... 53 1e-06
AB058724-1|BAB47450.1| 609|Homo sapiens KIAA1821 protein protein. 53 1e-06
X05276-1|CAA28888.1| 248|Homo sapiens protein ( Human mRNA for ... 52 2e-06
M19714-1|AAA61226.1| 264|Homo sapiens TPM1 protein. 52 2e-06
M19713-1|AAA61225.1| 284|Homo sapiens TPM1 protein. 52 2e-06
BT019634-1|AAV38440.1| 248|Homo sapiens tropomyosin 4 protein. 52 2e-06
BC067225-1|AAH67225.1| 248|Homo sapiens tropomyosin 4 protein. 52 2e-06
BC067085-1|AAH67085.1| 615|Homo sapiens HIP1R protein protein. 52 2e-06
BC037576-1|AAH37576.1| 248|Homo sapiens tropomyosin 4 protein. 52 2e-06
AK131384-1|BAD18535.1| 326|Homo sapiens protein ( Homo sapiens ... 52 2e-06
AF310722-1|AAK17926.1| 320|Homo sapiens tropomyosin 4-anaplasti... 52 2e-06
AF186109-1|AAG17014.1| 237|Homo sapiens TPM4-ALK fusion oncopro... 52 2e-06
AB014555-1|BAA31630.1| 1083|Homo sapiens KIAA0655 protein protein. 52 2e-06
AB013384-1|BAA33713.1| 890|Homo sapiens HIP1R protein. 52 2e-06
X06825-1|CAA29971.1| 284|Homo sapiens protein ( Human mRNA for ... 52 2e-06
U72849-1|AAD00186.1| 2033|Homo sapiens envoplakin protein. 52 2e-06
U53786-1|AAC64662.1| 2033|Homo sapiens envoplakin protein. 52 2e-06
BC126105-1|AAI26106.1| 2033|Homo sapiens envoplakin protein. 52 2e-06
BC126103-1|AAI26104.1| 2033|Homo sapiens envoplakin protein. 52 2e-06
BC002827-1|AAH02827.1| 248|Homo sapiens tropomyosin 4 protein. 52 2e-06
AL133410-4|CAI10977.1| 284|Homo sapiens tropomyosin 2 (beta) pr... 52 2e-06
AK023385-1|BAB14554.1| 284|Homo sapiens protein ( Homo sapiens ... 52 2e-06
AF039690-1|AAC18039.1| 414|Homo sapiens antigen NY-CO-8 protein. 52 2e-06
Z11583-1|CAA77669.1| 2115|Homo sapiens NuMA protein protein. 52 3e-06
X82834-1|CAA58041.1| 2185|Homo sapiens 256 kD golgin protein. 52 3e-06
X78998-1|CAA55632.1| 1411|Homo sapiens endosomal protein protein. 52 3e-06
U41740-1|AAC50434.1| 2230|Homo sapiens trans-Golgi p230 protein. 52 3e-06
L40157-1|AAA79121.1| 1410|Homo sapiens endosome-associated prote... 52 3e-06
BC000616-1|AAH00616.1| 585|Homo sapiens SWAP-70 protein protein. 52 3e-06
AL590431-10|CAH71268.1| 247|Homo sapiens tropomyosin 3 protein. 52 3e-06
AF210818-1|AAF24486.1| 585|Homo sapiens SWAP-70 protein. 52 3e-06
AF134894-1|AAF61403.1| 585|Homo sapiens SWAP-70 homolog protein. 52 3e-06
AB210007-1|BAE06089.1| 2121|Homo sapiens NUMA1 variant protein p... 52 3e-06
AB209996-1|BAE06078.1| 2585|Homo sapiens CENPE variant protein p... 52 3e-06
AB209693-1|BAD92930.1| 1310|Homo sapiens golgi autoantigen, golg... 52 3e-06
AB208841-1|BAD92078.1| 1585|Homo sapiens Nuclear mitotic apparat... 52 3e-06
AB014540-1|BAA31615.1| 603|Homo sapiens KIAA0640 protein protein. 52 3e-06
X04627-1|CAA28300.1| 258|Homo sapiens beta-myosin heavy chain p... 51 4e-06
X04201-1|CAA27798.1| 285|Homo sapiens protein ( Human skeletal ... 51 4e-06
BC008425-1|AAH08425.1| 285|Homo sapiens tropomyosin 3 protein. 51 4e-06
BC008407-1|AAH08407.1| 285|Homo sapiens tropomyosin 3 protein. 51 4e-06
AL590431-12|CAH71269.1| 284|Homo sapiens tropomyosin 3 protein. 51 4e-06
AL590431-11|CAH71270.1| 242|Homo sapiens tropomyosin 3 protein. 51 4e-06
AK092690-1|BAC03946.1| 243|Homo sapiens protein ( Homo sapiens ... 51 4e-06
DQ120629-1|ABB92415.1| 1185|Homo sapiens KIF4B protein. 51 5e-06
AL590431-9|CAH71267.1| 248|Homo sapiens tropomyosin 3 protein. 51 5e-06
M75165-1|AAB59509.1| 284|Homo sapiens tropomyosin protein. 50 9e-06
M74817-1|AAA61230.1| 284|Homo sapiens tropomyosin-1 protein. 50 9e-06
M12125-1|AAA36773.1| 284|Homo sapiens protein ( Human fibroblas... 50 9e-06
BC101520-1|AAI01521.1| 1194|Homo sapiens protein tyrosine phosph... 50 9e-06
BC101518-1|AAI01519.1| 1194|Homo sapiens protein tyrosine phosph... 50 9e-06
BC060796-1|AAH60796.1| 684|Homo sapiens coiled-coil domain cont... 50 9e-06
BC011776-1|AAH11776.1| 284|Homo sapiens tropomyosin 2 (beta) pr... 50 9e-06
AY254201-1|AAP13075.1| 682|Homo sapiens aaa-protein protein. 50 9e-06
AL133410-2|CAI10974.1| 284|Homo sapiens tropomyosin 2 (beta) pr... 50 9e-06
AK223258-1|BAD96978.1| 284|Homo sapiens tropomyosin 2 (beta) is... 50 9e-06
AF209746-1|AAF17621.1| 257|Homo sapiens beta tropomyosin protein. 50 9e-06
AB014554-1|BAA31629.2| 1267|Homo sapiens KIAA0654 protein protein. 50 9e-06
Z29074-1|CAA82315.1| 623|Homo sapiens cytokeratin 9 protein. 50 1e-05
X75015-1|CAA52924.1| 622|Homo sapiens keratin 9 protein. 50 1e-05
X03541-1|CAA27243.1| 641|Homo sapiens protein ( Human mRNA of t... 50 1e-05
S69510-1|AAC60619.1| 622|Homo sapiens cytokeratin 9 protein. 50 1e-05
M77830-1|AAA85135.1| 2871|Homo sapiens desmoplakin I protein. 50 1e-05
J05211-1|AAA35766.1| 1752|Homo sapiens protein ( Human desmoplak... 50 1e-05
BC121170-1|AAI21171.1| 467|Homo sapiens KRT9 protein protein. 50 1e-05
BC029811-1|AAH29811.1| 562|Homo sapiens hypothetical protein FL... 50 1e-05
AL133410-3|CAI10976.1| 322|Homo sapiens tropomyosin 2 (beta) pr... 50 1e-05
AL133410-1|CAI10975.1| 284|Homo sapiens tropomyosin 2 (beta) pr... 50 1e-05
AL031058-1|CAA19927.1| 2871|Homo sapiens desmoplakin protein. 50 1e-05
AK128169-1|BAC87306.1| 640|Homo sapiens in, 230kDa subunit) (TN... 50 1e-05
AK057220-1|BAB71384.1| 562|Homo sapiens protein ( Homo sapiens ... 50 1e-05
U52962-1|AAD10838.1| 3321|Homo sapiens kendrin protein. 49 2e-05
BC150210-1|AAI50211.1| 1253|Homo sapiens PHLDB2 protein protein. 49 2e-05
BC142678-1|AAI42679.1| 1253|Homo sapiens PHLDB2 protein protein. 49 2e-05
BC108904-1|AAI08905.1| 725|Homo sapiens hyaluronan-mediated mot... 49 2e-05
BC070281-1|AAH70281.1| 552|Homo sapiens HMMR protein protein. 49 2e-05
BC006984-1|AAH06984.1| 512|Homo sapiens Unknown (protein for IM... 49 2e-05
AL590431-7|CAH71266.1| 248|Homo sapiens tropomyosin 3 protein. 49 2e-05
AL451125-2|CAI14346.1| 767|Homo sapiens golgi autoantigen, golg... 49 2e-05
AL354928-1|CAI39632.1| 767|Homo sapiens golgi autoantigen, golg... 49 2e-05
AK125555-1|BAC86200.1| 373|Homo sapiens protein ( Homo sapiens ... 49 2e-05
AK092996-1|BAC04014.1| 787|Homo sapiens protein ( Homo sapiens ... 49 2e-05
AJ496194-1|CAD42711.1| 1253|Homo sapiens LL5 beta protein protein. 49 2e-05
AF515282-1|AAP46636.1| 3336|Homo sapiens pericentrin B protein. 49 2e-05
AF474157-1|AAL84570.1| 247|Homo sapiens TPMsk3 protein. 49 2e-05
AF282265-1|AAF87584.1| 919|Homo sapiens inner centromere protei... 49 2e-05
AB209903-1|BAD93140.1| 1259|Homo sapiens LL5 beta protein varian... 49 2e-05
AB019691-1|BAA78718.1| 3899|Homo sapiens Centrosome- and Golgi-l... 49 2e-05
AB007862-1|BAA23698.3| 3284|Homo sapiens KIAA0402 protein. 49 2e-05
Z11584-1|CAA77670.1| 2101|Homo sapiens NuMA protein protein. 49 2e-05
BC057235-1|AAH57235.1| 613|Homo sapiens HMMR protein protein. 49 2e-05
BC018933-1|AAH18933.2| 931|Homo sapiens MYH14 protein protein. 49 2e-05
BC011615-1|AAH11615.2| 739|Homo sapiens AZI1 protein protein. 49 2e-05
AY004867-1|AAF87083.1| 247|Homo sapiens tropomyosin isoform pro... 49 2e-05
AJ417067-1|CAD01135.1| 1286|Homo sapiens RPGR-interacting protei... 49 2e-05
AJ417048-1|CAD01136.1| 1286|Homo sapiens RPGR-interacting protei... 49 2e-05
AJ131693-1|CAB40713.1| 3908|Homo sapiens AKAP450 protein protein. 49 2e-05
AJ010770-1|CAA09361.1| 3911|Homo sapiens Hyperion protein protein. 49 2e-05
AF091711-1|AAD39719.1| 1773|Homo sapiens splice variant AKAP350 ... 49 2e-05
AF083037-1|AAD22767.1| 3595|Homo sapiens A-kinase anchoring prot... 49 2e-05
AF032862-1|AAC32548.1| 724|Homo sapiens intracellular hyaluroni... 49 2e-05
AC004013-1|AAB96867.2| 2058|Homo sapiens unknown protein. 49 2e-05
AB029041-1|BAA83070.1| 1165|Homo sapiens KIAA1118 protein protein. 49 2e-05
AB018346-1|BAA34523.1| 1708|Homo sapiens KIAA0803 protein protein. 49 2e-05
D86958-1|BAA13194.2| 1593|Homo sapiens KIAA0203 protein. 48 3e-05
BC130453-1|AAI30454.1| 1726|Homo sapiens ANKRD26 protein protein. 48 3e-05
BC050281-1|AAH50281.1| 1011|Homo sapiens PPFIBP1 protein protein. 48 3e-05
BC017556-1|AAH17556.1| 1594|Homo sapiens RB1-inducible coiled-co... 48 3e-05
AL162272-4|CAC19649.1| 1710|Homo sapiens novel protein protein. 48 3e-05
AK092201-1|BAC03827.1| 284|Homo sapiens protein ( Homo sapiens ... 48 3e-05
AB059622-1|BAB69690.1| 1594|Homo sapiens Rb1-inducible coiled co... 48 3e-05
AB033056-1|BAA86544.2| 932|Homo sapiens KIAA1230 protein protein. 48 3e-05
AB028997-1|BAA83026.2| 1715|Homo sapiens KIAA1074 protein protein. 48 3e-05
X04588-1|CAB37185.1| 248|Homo sapiens protein ( Human 2.5 kb mR... 48 4e-05
U29343-1|AAC52049.1| 725|Homo sapiens hyaluronan receptor protein. 48 4e-05
BC132736-1|AAI32737.1| 1843|Homo sapiens coiled-coil domain cont... 48 4e-05
BC098576-1|AAH98576.1| 918|Homo sapiens inner centromere protei... 48 4e-05
BC072428-1|AAH72428.1| 248|Homo sapiens tropomyosin 3 protein. 48 4e-05
BC015403-1|AAH15403.1| 248|Homo sapiens tropomyosin 3 protein. 48 4e-05
BC007433-1|AAH07433.1| 284|Homo sapiens tropomyosin 1 (alpha) p... 48 4e-05
BC000771-1|AAH00771.1| 248|Homo sapiens tropomyosin 3 protein. 48 4e-05
AY714053-1|AAU04398.1| 918|Homo sapiens inner centromere protei... 48 4e-05
AL590431-8|CAH71264.1| 248|Homo sapiens tropomyosin 3 protein. 48 4e-05
AL590431-6|CAH71265.1| 232|Homo sapiens tropomyosin 3 protein. 48 4e-05
AK097424-1|BAC05045.1| 535|Homo sapiens protein ( Homo sapiens ... 48 4e-05
AF273047-1|AAG34907.1| 623|Homo sapiens CTCL tumor antigen se20... 48 4e-05
AB201172-1|BAE44387.1| 1870|Homo sapiens girdin protein. 48 4e-05
AB125644-1|BAF44475.1| 1843|Homo sapiens PKB/Akt-binding protein... 48 4e-05
Z98949-1|CAI17892.1| 2566|Homo sapiens protein ( Human DNA seque... 48 5e-05
M19267-1|AAA36771.1| 284|Homo sapiens protein ( Human tropomyos... 48 5e-05
D11393-1|BAA01989.1| 208|Homo sapiens human non-muscle myosin h... 48 5e-05
BC066123-1|AAH66123.1| 390|Homo sapiens polymerase I and transc... 48 5e-05
BC050327-1|AAH50327.1| 697|Homo sapiens Leber congenital amauro... 48 5e-05
AY077700-1|AAL75811.1| 2568|Homo sapiens myosin-like protein pro... 48 5e-05
AL391840-1|CAC37303.1| 697|Homo sapiens chromosome 6 open readi... 48 5e-05
AL080245-1|CAI16965.1| 2566|Homo sapiens protein ( Human DNA seq... 48 5e-05
AL079300-1|CAI17881.1| 2566|Homo sapiens protein ( Human DNA seq... 48 5e-05
AL022329-3|CAI17968.1| 2566|Homo sapiens protein ( Human DNA seq... 48 5e-05
AJ310932-1|CAC70714.3| 2567|Homo sapiens myosin heavy chain prot... 48 5e-05
AJ310931-1|CAC70712.2| 2567|Homo sapiens myosin heavy chain prot... 48 5e-05
AF250731-1|AAO27830.1| 713|Homo sapiens centrosomal colon cance... 48 5e-05
AF092563-1|AAC72360.1| 1197|Homo sapiens chromosome-associated p... 48 5e-05
AB075376-1|BAC16363.1| 2567|Homo sapiens bk125H2.1 protein. 48 5e-05
AB042648-1|BAB55550.2| 2080|Homo sapiens bk125H2.1 protein. 48 5e-05
Z15005-1|CAA78727.1| 2663|Homo sapiens CENP-E protein. 47 7e-05
BC146789-1|AAI46790.1| 1583|Homo sapiens GRIP and coiled-coil do... 47 7e-05
BC133019-1|AAI33020.1| 1427|Homo sapiens CCDC144A protein protein. 47 7e-05
BC013023-1|AAH13023.1| 1193|Homo sapiens NUMA1 protein protein. 47 7e-05
AK128577-1|BAC87508.1| 1080|Homo sapiens protein ( Homo sapiens ... 47 7e-05
AC012487-1|AAX88838.1| 1583|Homo sapiens unknown protein. 47 7e-05
AB075522-1|BAE45765.1| 484|Homo sapiens putative protein produc... 47 7e-05
AB011137-1|BAA25491.2| 641|Homo sapiens KIAA0565 protein protein. 47 7e-05
AB002334-1|BAA20794.2| 1635|Homo sapiens KIAA0336 protein. 47 7e-05
Y12490-1|CAA73095.1| 1979|Homo sapiens Golgi-associated microtub... 47 9e-05
X12369-1|CAA30930.1| 227|Homo sapiens tropomyosin (227 AA) prot... 47 9e-05
L01042-1|AAD54608.1| 1093|Homo sapiens TATA element modulatory f... 47 9e-05
DQ139275-1|ABA43896.1| 1313|Homo sapiens Tax1-binding protein 2 ... 47 9e-05
BX641024-1|CAE46015.1| 1694|Homo sapiens hypothetical protein pr... 47 9e-05
BX284668-3|CAH70057.1| 1898|Homo sapiens ciliary rootlet coiled-... 47 9e-05
BX284668-2|CAH70055.1| 2017|Homo sapiens ciliary rootlet coiled-... 47 9e-05
BC150248-1|AAI50249.1| 992|Homo sapiens ELKS/RAB6-interacting/C... 47 9e-05
BC126123-1|AAI26124.1| 1093|Homo sapiens TATA element modulatory... 47 9e-05
BC117418-1|AAI17419.1| 1093|Homo sapiens TATA element modulatory... 47 9e-05
BC068006-1|AAH68006.1| 627|Homo sapiens ERC1 protein protein. 47 9e-05
BC051733-1|AAH51733.1| 1026|Homo sapiens LUZP1 protein protein. 47 9e-05
BC008345-1|AAH08345.1| 963|Homo sapiens Unknown (protein for IM... 47 9e-05
AL049569-4|CAI20365.1| 1898|Homo sapiens ciliary rootlet coiled-... 47 9e-05
AL049569-3|CAI20363.1| 2017|Homo sapiens ciliary rootlet coiled-... 47 9e-05
AL031428-1|CAI19705.1| 1026|Homo sapiens leucine zipper protein ... 47 9e-05
AK124447-1|BAC85854.1| 434|Homo sapiens protein ( Homo sapiens ... 47 9e-05
AK097517-1|BAC05084.1| 621|Homo sapiens protein ( Homo sapiens ... 47 9e-05
AK074153-1|BAB84979.1| 1046|Homo sapiens FLJ00226 protein protein. 47 9e-05
AF007217-1|AAD09135.1| 1978|Homo sapiens Trip230 protein. 47 9e-05
AB209109-1|BAD92346.1| 1096|Homo sapiens TATA element modulatory... 47 9e-05
AB053470-1|BAC54109.1| 1088|Homo sapiens ELKS delta protein. 47 9e-05
AB053468-1|BAC54107.1| 992|Homo sapiens ELKS beta protein. 47 9e-05
AB029004-1|BAA83033.2| 1003|Homo sapiens KIAA1081 protein protein. 47 9e-05
AB018345-1|BAA34522.2| 1578|Homo sapiens KIAA0802 protein protein. 47 9e-05
AB015617-1|BAA88763.1| 948|Homo sapiens ELKS protein. 47 9e-05
AB007914-1|BAA32290.2| 1919|Homo sapiens KIAA0445 protein protein. 47 9e-05
BC130385-1|AAI30386.1| 1197|Homo sapiens structural maintenance ... 46 1e-04
BC104912-1|AAI04913.1| 1236|Homo sapiens PPFIA2 protein protein. 46 1e-04
BC078168-1|AAH78168.1| 887|Homo sapiens CCDC88A protein protein. 46 1e-04
BC035617-1|AAH35617.1| 642|Homo sapiens NDC80 homolog, kinetoch... 46 1e-04
BC023021-1|AAH23021.1| 731|Homo sapiens golgi autoantigen, golg... 46 1e-04
BC012568-1|AAH12568.1| 605|Homo sapiens coiled-coil domain cont... 46 1e-04
AY736182-1|AAU86898.1| 1989|Homo sapiens ninein isoform 6 protein. 46 1e-04
AY644768-1|AAV85456.1| 731|Homo sapiens cell proliferation-indu... 46 1e-04
AY517557-1|AAT44530.1| 605|Homo sapiens hypothetical rhabdomyos... 46 1e-04
AL354938-1|CAI16923.1| 1197|Homo sapiens structural maintenance ... 46 1e-04
AL161791-1|CAI16866.1| 1197|Homo sapiens structural maintenance ... 46 1e-04
AL139421-4|CAI22511.1| 720|Homo sapiens coiled-coil domain cont... 46 1e-04
AL139421-3|CAI22510.1| 1044|Homo sapiens coiled-coil domain cont... 46 1e-04
AL139421-1|CAI22508.1| 1454|Homo sapiens coiled-coil domain cont... 46 1e-04
AK126045-1|BAC86410.1| 978|Homo sapiens galactosaminyltransfera... 46 1e-04
AK000371-1|BAA91119.1| 413|Homo sapiens protein ( Homo sapiens ... 46 1e-04
AJ132949-1|CAB36967.1| 585|Homo sapiens rfg5 protein protein. 46 1e-04
AF302773-1|AAG33512.2| 2090|Homo sapiens ninein-Lm isoform protein. 46 1e-04
AF212162-1|AAF23015.2| 2096|Homo sapiens ninein protein. 46 1e-04
AF085199-1|AAD09753.1| 731|Homo sapiens golgin-84 protein. 46 1e-04
AF017790-1|AAB80726.1| 642|Homo sapiens retinoblastoma-associat... 46 1e-04
AB210009-1|BAE06091.1| 1258|Homo sapiens PPFIA2 variant protein ... 46 1e-04
CR456946-1|CAG33227.1| 427|Homo sapiens FLOT1 protein. 46 2e-04
BX538286-1|CAD98081.1| 724|Homo sapiens hypothetical protein pr... 46 2e-04
BX248307-9|CAM25936.1| 427|Homo sapiens flotillin 1 protein. 46 2e-04
BT007077-1|AAP35740.1| 427|Homo sapiens flotillin 1 protein. 46 2e-04
BC039237-1|AAH39237.1| 543|Homo sapiens neurofilament, light po... 46 2e-04
BC001146-1|AAH01146.1| 427|Homo sapiens flotillin 1 protein. 46 2e-04
BA000025-68|BAB63320.1| 427|Homo sapiens FLOT1 protein. 46 2e-04
AY156690-1|AAN74826.1| 543|Homo sapiens light molecular weight ... 46 2e-04
AL845353-27|CAI41896.1| 427|Homo sapiens flotillin 1 protein. 46 2e-04
AL662848-10|CAI17443.1| 427|Homo sapiens flotillin 1 protein. 46 2e-04
AL662797-14|CAI18202.1| 427|Homo sapiens flotillin 1 protein. 46 2e-04
AL121586-8|CAO03346.1| 209|Homo sapiens centrosomal protein 250... 46 2e-04
AF089750-1|AAC35387.1| 427|Homo sapiens flotillin-1 protein. 46 2e-04
AB202099-2|BAE78620.1| 427|Homo sapiens flotillin 1 protein. 46 2e-04
AB103607-2|BAF31269.1| 427|Homo sapiens FLOT1 protein protein. 46 2e-04
AB088101-2|BAC54934.1| 427|Homo sapiens flotillin 1 protein. 46 2e-04
AB014535-1|BAA31610.2| 864|Homo sapiens KIAA0635 protein protein. 46 2e-04
DQ424903-1|ABD83668.1| 245|Homo sapiens tropomyosin 1 alpha var... 46 2e-04
AL590377-2|CAI14630.2| 1406|Homo sapiens chromosome 9 open readi... 46 2e-04
AL354738-1|CAI16195.2| 1406|Homo sapiens chromosome 9 open readi... 46 2e-04
AL354711-1|CAH72682.2| 1406|Homo sapiens chromosome 9 open readi... 46 2e-04
AL162725-3|CAH70424.1| 1406|Homo sapiens chromosome 9 open readi... 46 2e-04
AL135927-8|CAI15527.1| 491|Homo sapiens lamin A/C protein. 46 2e-04
AL135927-7|CAI15526.1| 513|Homo sapiens lamin A/C protein. 46 2e-04
AL133214-3|CAH70743.2| 1406|Homo sapiens chromosome 9 open readi... 46 2e-04
AK129882-1|BAC85248.1| 217|Homo sapiens protein ( Homo sapiens ... 46 2e-04
AK091682-1|BAC03719.1| 936|Homo sapiens protein ( Homo sapiens ... 46 2e-04
AK000283-1|BAA91052.1| 1084|Homo sapiens protein ( Homo sapiens ... 46 2e-04
Z24727-1|CAA80853.1| 243|Homo sapiens tropomyosin isoform protein. 45 3e-04
U93121-1|AAB88727.1| 753|Homo sapiens M-phase phosphoprotein-1 ... 45 3e-04
M19715-1|AAA61227.1| 229|Homo sapiens TPM1 protein. 45 3e-04
BX538186-1|CAD98058.1| 971|Homo sapiens hypothetical protein pr... 45 3e-04
BC060769-1|AAH60769.2| 1107|Homo sapiens chromosome 6 open readi... 45 3e-04
BC012003-1|AAH12003.1| 365|Homo sapiens CEP135 protein protein. 45 3e-04
BC001421-1|AAH01421.1| 335|Homo sapiens nudE nuclear distributi... 45 3e-04
AY739715-1|AAW65984.1| 617|Homo sapiens M-phase phosphoprotein ... 45 3e-04
AY282407-1|AAP40331.1| 1116|Homo sapiens M-phase phosphoprotein ... 45 3e-04
AY131226-1|AAN07912.1| 681|Homo sapiens medulloblastoma antigen... 45 3e-04
AL365275-1|CAI40383.1| 1140|Homo sapiens chromosome 6 open readi... 45 3e-04
AL157400-6|CAI16830.1| 1820|Homo sapiens M-phase phosphoprotein ... 45 3e-04
AL157400-5|CAI16831.1| 1780|Homo sapiens M-phase phosphoprotein ... 45 3e-04
AL157389-3|CAI12886.1| 1820|Homo sapiens M-phase phosphoprotein ... 45 3e-04
AL157389-2|CAI12887.1| 1780|Homo sapiens M-phase phosphoprotein ... 45 3e-04
AL137009-1|CAI20344.1| 1140|Homo sapiens chromosome 6 open readi... 45 3e-04
AL132874-2|CAI42604.1| 1140|Homo sapiens chromosome 6 open readi... 45 3e-04
AK127744-1|BAC87110.1| 600|Homo sapiens protein ( Homo sapiens ... 45 3e-04
AK092712-1|BAC03956.1| 183|Homo sapiens protein ( Homo sapiens ... 45 3e-04
AK000108-1|BAA90949.1| 335|Homo sapiens protein ( Homo sapiens ... 45 3e-04
AB033337-1|BAB69456.1| 1820|Homo sapiens mitotic kinesin-related... 45 3e-04
Z32858-1|CAA83687.1| 119|Homo sapiens fast 2a myosin heavy chai... 45 4e-04
L16782-1|AAC37542.1| 566|Homo sapiens putative M phase phosphop... 45 4e-04
DQ109808-1|AAZ83370.1| 2479|Homo sapiens nephrocystin-6 protein. 45 4e-04
BC131805-1|AAI31806.1| 913|Homo sapiens CCDC46 protein protein. 45 4e-04
BC052988-1|AAH52988.1| 980|Homo sapiens retinoic acid induced 1... 45 4e-04
BC050548-1|AAH50548.1| 1127|Homo sapiens KIF4A protein protein. 45 4e-04
BC043398-1|AAH43398.1| 805|Homo sapiens CEP290 protein protein. 45 4e-04
BC033900-1|AAH33900.1| 335|Homo sapiens NDE1 protein protein. 45 4e-04
BC011621-1|AAH11621.1| 728|Homo sapiens hook homolog 1 (Drosoph... 45 4e-04
BC003664-1|AAH03664.1| 787|Homo sapiens Unknown (protein for IM... 45 4e-04
AL591543-1|CAI17285.1| 992|Homo sapiens ankyrin repeat domain 1... 45 4e-04
AL589649-3|CAH71820.1| 1213|Homo sapiens filamin A interacting p... 45 4e-04
AL589649-1|CAH71818.1| 1114|Homo sapiens filamin A interacting p... 45 4e-04
AL451082-2|CAH72276.1| 1194|Homo sapiens protein tyrosine phosph... 45 4e-04
AL445465-2|CAH73615.1| 1213|Homo sapiens filamin A interacting p... 45 4e-04
AL445465-1|CAH73614.1| 1114|Homo sapiens filamin A interacting p... 45 4e-04
AL357752-3|CAI41487.1| 1232|Homo sapiens kinesin family member 4... 45 4e-04
AL139398-5|CAI41024.1| 1232|Homo sapiens kinesin family member 4... 45 4e-04
AL035416-6|CAI22779.1| 728|Homo sapiens hook homolog 1 (Drosoph... 45 4e-04
AK097021-1|BAC04928.1| 512|Homo sapiens protein ( Homo sapiens ... 45 4e-04
AK023677-1|BAB14636.1| 574|Homo sapiens protein ( Homo sapiens ... 45 4e-04
AJ271784-1|CAB75427.1| 1232|Homo sapiens chromokinesin protein. 45 4e-04
AF317887-1|AAK01919.1| 589|Homo sapiens monoclonal antibody 3H1... 45 4e-04
AF179308-1|AAD51855.1| 1232|Homo sapiens KIF4 protein. 45 4e-04
AF044923-1|AAC09298.1| 728|Homo sapiens hook1 protein protein. 45 4e-04
AB208797-1|BAD92034.1| 1235|Homo sapiens Chromosome-associated k... 45 4e-04
AB095935-1|BAC23111.1| 996|Homo sapiens KIAA2015 protein protein. 45 4e-04
AB086011-1|BAC77067.1| 1213|Homo sapiens L-FILIP protein. 45 4e-04
AB037755-1|BAA92572.1| 989|Homo sapiens KIAA1334 protein protein. 45 4e-04
AB033101-1|BAA86589.1| 1140|Homo sapiens KIAA1275 protein protein. 45 4e-04
U30872-1|AAA82935.1| 3113|Homo sapiens mitosin protein. 44 5e-04
>X52889-1|CAA37068.1| 1934|Homo sapiens cardiac beta myosin heavy
chain protein.
Length = 1934
Score = 233 bits (571), Expect = 4e-61
Identities = 110/235 (46%), Positives = 167/235 (71%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
V+++GEQ+D L ++K K EK ++++ E++D+ + ++ + KA EK+ + L+ Q+NE
Sbjct: 1200 VAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEH 1259
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
+SKA+E R++NDL + + KL EN +L RQL+E E+ +SQL++ K++ T QLED KR
Sbjct: 1260 RSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQL 1319
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEG 559
+EE + + L ++ HD D +REQ EEE E KA+LQR LSKAN+E WR+KYE++
Sbjct: 1320 EEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDA 1379
Query: 560 VARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
+ R+EELEEAK+KL RL EAEE +E++N K +LEKTK RL E+EDL ++V+R
Sbjct: 1380 IQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVER 1434
Score = 72.5 bits (170), Expect = 2e-12
Identities = 52/239 (21%), Positives = 113/239 (47%), Gaps = 3/239 (1%)
Frame = +2
Query: 14 RFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLN 193
R V + LD + + +A + + + ++N++ L H + A +K VK LQ L
Sbjct: 1592 RVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLK 1651
Query: 194 EVQSKADEANRTLNDLDAAKKKLSI--ENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDT 367
+ Q + D+A R +DL K+ ++I ++L +LEE + V Q + + +L +T
Sbjct: 1652 DTQIQLDDAVRANDDL---KENIAIVERRNNLQAELEELRAVVEQTERSRKLADRELIET 1708
Query: 368 KRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKY 547
+ +L+ + + ++ DL ++ +VEE + + + + KA +A + +
Sbjct: 1709 SERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEEL 1768
Query: 548 ESEGVARSEELEEAKRKLQARLAEAEETIESLNQ-KVVALEKTKQRLATEVEDLQLEVD 721
+ E S LE K+ ++ + + + ++ Q + +K Q+L V +L+ E++
Sbjct: 1769 KKE-QDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELE 1826
Score = 69.3 bits (162), Expect = 1e-11
Identities = 59/235 (25%), Positives = 108/235 (45%), Gaps = 1/235 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+ D+ + D++N L K + + +V+DL L+ + E+ ++L+ L
Sbjct: 1007 LDDLQAEEDKVNTLT----KAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLT 1062
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
Q + LD KK E + L ++E+ ++ SQL K L ++E+ +
Sbjct: 1063 QESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEEL 1122
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKAN-AEAQLWRSKYESE 556
+ E RA + +L +L+ I E++EE A G Q +++K AE Q R E E
Sbjct: 1123 EAERTARAKVEKLRSDLSRELEEISERLEE-AGGATSCQIEMNKKREAEFQKMRRDLE-E 1180
Query: 557 GVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
+ E A RK A +++ L +++ L++ KQ+L E + +LE+D
Sbjct: 1181 ATLQHEATAAALRKKHA------DSVAELGEQIDNLQRVKQKLEKEKSEFKLELD 1229
Score = 64.9 bits (151), Expect = 3e-10
Identities = 50/231 (21%), Positives = 103/231 (44%), Gaps = 1/231 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+ D+ QL++ K K + + LR + + KA ++++ + ++ +
Sbjct: 1312 LEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQW 1371
Query: 200 QSKAD-EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRL 376
++K + +A + +L+ AKKKL+ + +E ++ S L K K L ++ED
Sbjct: 1372 RTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVD 1431
Query: 377 ADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESE 556
+ A L K RN + L +++ EE Q++ + E ++ YE E
Sbjct: 1432 VERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYE-E 1490
Query: 557 GVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQ 709
+ E + + LQ +++ E + S + + LEK +++L E +LQ
Sbjct: 1491 SLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQ 1541
Score = 57.2 bits (132), Expect = 6e-08
Identities = 45/235 (19%), Positives = 105/235 (44%), Gaps = 1/235 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+SD+ EQL K + EK R Q +E +L++ L+ +E + + Q + N++
Sbjct: 1509 ISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQI 1568
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQV-SQLSKIKVSLTTQLEDTKRL 376
+++ + ++ K+ + D L+ +AE++ ++ ++K + L + +
Sbjct: 1569 KAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQ 1628
Query: 377 ADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESE 556
R A + ++L+ L + + Q+++ DL+ ++ L E
Sbjct: 1629 LSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLQAELEELR 1688
Query: 557 GVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
V E+ E +++ L E E ++ L+ + +L K+++ ++ LQ EV+
Sbjct: 1689 AVV--EQTERSRKLADRELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVE 1741
Score = 56.8 bits (131), Expect = 8e-08
Identities = 49/225 (21%), Positives = 100/225 (44%), Gaps = 6/225 (2%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+ ++ E+L+ +AK EK R+ E+ ++ L+ + Q ++ K+ + + ++
Sbjct: 1115 IEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSCQIEMNKKREAEFQKM 1174
Query: 200 QSKADEANRTLNDLDAAKKKLSIEN-SDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRL 376
+ +EA AA +K ++ ++L Q++ + +L K K +L+D
Sbjct: 1175 RRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSN 1234
Query: 377 ADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAE-AQLWRSKYES 553
++ + +A L R LE ++ R + EE DL Q +K E +L R E
Sbjct: 1235 MEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEK 1294
Query: 554 EGVARSEELEEAK----RKLQARLAEAEETIESLNQKVVALEKTK 676
E A +L K ++L+ + EE +++ N AL+ +
Sbjct: 1295 E--ALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSAR 1337
Score = 56.0 bits (129), Expect = 1e-07
Identities = 48/214 (22%), Positives = 103/214 (48%), Gaps = 7/214 (3%)
Frame = +2
Query: 101 EVNDLRAGLDHLSNEKAAQ-EKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENS 277
E N ++A ++ EK + E+ + ++ +Q+ D R+ N+ KKK+ + +
Sbjct: 1564 EFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLN 1623
Query: 278 DLLRQLEEAESQVSQLSKIKVSLTTQLEDTK-RL-----ADEEARERATLLGKFRNLEHD 439
++ QL A ++ K SL + L+DT+ +L A+++ +E ++ + NL+ +
Sbjct: 1624 EMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLQAE 1683
Query: 440 LDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAE 619
L+ +R VE+ + R+L + + QL S+ S + + ++++ +LQ + E
Sbjct: 1684 LEELRAVVEQTERSRKLADRELIETSERVQLLHSQNTSL-INQKKKMDADLSQLQTEVEE 1742
Query: 620 AEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
A + + +K +K A E+L+ E D
Sbjct: 1743 AVQECRNAEEKA---KKAITDAAMMAEELKKEQD 1773
Score = 54.4 bits (125), Expect = 4e-07
Identities = 39/228 (17%), Positives = 98/228 (42%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
V D+ L+Q K++ E+ + + ++ + + L N+K ++ +K+ +LN +
Sbjct: 1031 VDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNAL 1090
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
++ ++ + L K+L +L +LE + +++ K++ L+ +LE+
Sbjct: 1091 NARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERL 1150
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEG 559
+E + + + E + +R +EE L K +A++ +
Sbjct: 1151 EEAGGATSCQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNL 1210
Query: 560 VARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVED 703
++LE+ K + + L + +E + + LEK + L ++ +
Sbjct: 1211 QRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNE 1258
Score = 52.4 bits (120), Expect = 2e-06
Identities = 57/244 (23%), Positives = 110/244 (45%), Gaps = 19/244 (7%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQ-EKIVKQLQHQLNEVQSKA 211
EQ ++ + KA+ ++ ++ SEV R + + ++ + E+ K+L +L E +
Sbjct: 1345 EQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAV 1404
Query: 212 DEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADE-- 385
+ N + L+ K +L E DL+ +E + + + L K + + L + K+ +E
Sbjct: 1405 EAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQ 1464
Query: 386 --------EARERATLLGKFRN-----LEHDLDNIREQVEEEAEGKADLQRQLSKANA-- 520
EAR +T L K +N LEH L+ + + + E +DL QL +
Sbjct: 1465 SELESSQKEARSLSTELFKLKNAYEESLEH-LETFKRENKNLQEEISDLTEQLGSSGKTI 1523
Query: 521 -EAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEV 697
E + R + E+E + LEEA+ L+ + NQ +E+ +LA +
Sbjct: 1524 HELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIER---KLAEKD 1580
Query: 698 EDLQ 709
E+++
Sbjct: 1581 EEME 1584
Score = 50.0 bits (114), Expect = 9e-06
Identities = 39/169 (23%), Positives = 80/169 (47%), Gaps = 2/169 (1%)
Frame = +2
Query: 29 MGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSN-EKAAQEKIVKQLQHQLNEVQS 205
M E+L + A E+ + + DL+ LD +K +++L+ ++ E+++
Sbjct: 1764 MAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEN 1823
Query: 206 KADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADE 385
+ + + + +K +L Q EE + +L + L +++ KR A+E
Sbjct: 1824 ELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEE 1883
Query: 386 EARERATLLGKFRNLEHDLDNIREQVEEEAEGKADL-QRQLSKANAEAQ 529
+ T L KFR ++H+LD EAE +AD+ + Q++K A+++
Sbjct: 1884 AEEQANTNLSKFRKVQHELD--------EAEERADIAESQVNKLRAKSR 1924
Score = 48.8 bits (111), Expect = 2e-05
Identities = 46/210 (21%), Positives = 91/210 (43%), Gaps = 9/210 (4%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD 214
E L+ L K + + + E++DL L EK+ KQL+ + E+QS +
Sbjct: 1490 ESLEHLETFKRENKNLQ----EEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALE 1545
Query: 215 EANRTLNDLDAAKKKLSIE----NSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLAD 382
EA +L + + +E +++ R+L E + ++ Q + + + L+ + D
Sbjct: 1546 EAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTS---LD 1602
Query: 383 EEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSK-----ANAEAQLWRSKY 547
E R R L + +E DL+ + Q+ A+ Q+Q+ + + QL +
Sbjct: 1603 AETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVR 1662
Query: 548 ESEGVARSEELEEAKRKLQARLAEAEETIE 637
++ + + + E + LQA L E +E
Sbjct: 1663 ANDDLKENIAIVERRNNLQAELEELRAVVE 1692
Score = 48.4 bits (110), Expect = 3e-05
Identities = 64/256 (25%), Positives = 120/256 (46%), Gaps = 23/256 (8%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHL--SNEKAAQE-KIVKQ---LQ 181
+++M QL N++ A+A+K S + D + LD +N+ + IV++ LQ
Sbjct: 1622 LNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLQ 1681
Query: 182 HQLNEVQSKADE-------ANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLS---K 331
+L E+++ ++ A+R L + + L +N+ L+ Q ++ ++ +SQL +
Sbjct: 1682 AELEELRAVVEQTERSRKLADRELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVE 1741
Query: 332 IKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSK 511
V E+ + A +A A L K ++ L+ +++ +E+ + DLQ +L +
Sbjct: 1742 EAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIK---DLQHRLDE 1798
Query: 512 ANAEAQLWRSKYESEGVARSEELE---EAKRKLQAR----LAEAEETIESLNQKVVALEK 670
A A K + AR ELE EA++K A + ++E I+ L + K
Sbjct: 1799 AEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRK 1858
Query: 671 TKQRLATEVEDLQLEV 718
RL V+ LQL+V
Sbjct: 1859 NLLRLQDLVDKLQLKV 1874
Score = 43.6 bits (98), Expect = 8e-04
Identities = 49/202 (24%), Positives = 88/202 (43%), Gaps = 13/202 (6%)
Frame = +2
Query: 143 EKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQ 322
E A+ ++ L+ L + +++ E + L K L ++ L +AE + Q
Sbjct: 848 EMASMKEEFTALKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQ 907
Query: 323 LSKIKVSLTTQ-------LEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEG 481
L K K+ L + LED E A L K RN+E + ++ ++
Sbjct: 908 LIKNKIQLEAKVKEMNERLED-------EEEMNAELTAKKRNVEDECSELKRDID----- 955
Query: 482 KADLQRQLSKANAEAQLWRSKYE--SEGVARSEE----LEEAKRKLQARLAEAEETIESL 643
DL+ L+K E +K + +E +A +E L + K+ LQ +A + +++
Sbjct: 956 --DLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAE 1013
Query: 644 NQKVVALEKTKQRLATEVEDLQ 709
KV L K K +L +V+DL+
Sbjct: 1014 EDKVNTLTKAKVKLEQQVDDLE 1035
>X51591-1|CAA35940.1| 1151|Homo sapiens beta-myosin heavy chain (1151
AA) protein.
Length = 1151
Score = 233 bits (571), Expect = 4e-61
Identities = 110/235 (46%), Positives = 167/235 (71%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
V+++GEQ+D L ++K K EK ++++ E++D+ + ++ + KA EK+ + L+ Q+NE
Sbjct: 416 VAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEH 475
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
+SKA+E R++NDL + + KL EN +L RQL+E E+ +SQL++ K++ T QLED KR
Sbjct: 476 RSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQL 535
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEG 559
+EE + + L ++ HD D +REQ EEE E KA+LQR LSKAN+E WR+KYE++
Sbjct: 536 EEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDA 595
Query: 560 VARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
+ R+EELEEAK+KL RL EAEE +E++N K +LEKTK RL E+EDL ++V+R
Sbjct: 596 IQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVER 650
Score = 73.7 bits (173), Expect = 7e-13
Identities = 51/237 (21%), Positives = 109/237 (45%), Gaps = 1/237 (0%)
Frame = +2
Query: 14 RFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLN 193
R V + LD + + +A + + + ++N++ L H + A +K VK LQ L
Sbjct: 808 RVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLK 867
Query: 194 EVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKR 373
+ Q + D+A R +DL + N+ L +LEE + V Q + + +L +T
Sbjct: 868 DTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLADEELIETSE 927
Query: 374 LADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYES 553
+ +L+ + + ++ DL ++ +VEE + + + + KA +A + + +
Sbjct: 928 RVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKK 987
Query: 554 EGVARSEELEEAKRKLQARLAEAEETIESLNQ-KVVALEKTKQRLATEVEDLQLEVD 721
E S LE K+ ++ + + + ++ Q + +K Q+L V +L+ E++
Sbjct: 988 E-QDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELE 1043
Score = 68.5 bits (160), Expect = 3e-11
Identities = 58/235 (24%), Positives = 109/235 (46%), Gaps = 1/235 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+ D+ + D++N L K + + +V+DL L+ + E+ ++L+ L
Sbjct: 223 LDDLQAEEDKVNTLT----KAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLT 278
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
Q + L+ KK E + L ++E+ ++ SQL K L ++E+ +
Sbjct: 279 QESIMDLENDKQQLEERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEEL 338
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKAN-AEAQLWRSKYESE 556
+ E RA + +L +L+ I E++EE A G +Q +++K AE Q R E E
Sbjct: 339 EAERTARAKVEKLRSDLSRELEEISERLEE-AGGATSVQIEMNKKREAEFQKMRRDLE-E 396
Query: 557 GVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
+ E A RK A +++ L +++ L++ KQ+L E + +LE+D
Sbjct: 397 ATLQHEATAAALRKKHA------DSVAELGEQIDNLQRVKQKLEKEKSEFKLELD 445
Score = 64.9 bits (151), Expect = 3e-10
Identities = 50/231 (21%), Positives = 103/231 (44%), Gaps = 1/231 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+ D+ QL++ K K + + LR + + KA ++++ + ++ +
Sbjct: 528 LEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQW 587
Query: 200 QSKAD-EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRL 376
++K + +A + +L+ AKKKL+ + +E ++ S L K K L ++ED
Sbjct: 588 RTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVD 647
Query: 377 ADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESE 556
+ A L K RN + L +++ EE Q++ + E ++ YE E
Sbjct: 648 VERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYE-E 706
Query: 557 GVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQ 709
+ E + + LQ +++ E + S + + LEK +++L E +LQ
Sbjct: 707 SLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQ 757
Score = 58.8 bits (136), Expect = 2e-08
Identities = 46/235 (19%), Positives = 109/235 (46%), Gaps = 1/235 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+SD+ EQL K + EK R Q +E +L++ L+ +E + + Q + N++
Sbjct: 725 ISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQI 784
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQV-SQLSKIKVSLTTQLEDTKRL 376
+++ + ++ K+ + D L+ +AE++ ++ ++K + L + +
Sbjct: 785 KAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQ 844
Query: 377 ADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESE 556
R A + ++L+ L + + Q+++ DL+ ++ L +++ E E
Sbjct: 845 LSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELE-E 903
Query: 557 GVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
A E+ E +++ L E E ++ L+ + +L K+++ ++ LQ EV+
Sbjct: 904 LRAVVEQTERSRKLADEELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVE 958
Score = 56.8 bits (131), Expect = 8e-08
Identities = 49/225 (21%), Positives = 100/225 (44%), Gaps = 6/225 (2%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+ ++ E+L+ +AK EK R+ E+ ++ L+ + Q ++ K+ + + ++
Sbjct: 331 IEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKM 390
Query: 200 QSKADEANRTLNDLDAAKKKLSIEN-SDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRL 376
+ +EA AA +K ++ ++L Q++ + +L K K +L+D
Sbjct: 391 RRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSN 450
Query: 377 ADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAE-AQLWRSKYES 553
++ + +A L R LE ++ R + EE DL Q +K E +L R E
Sbjct: 451 MEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEK 510
Query: 554 EGVARSEELEEAK----RKLQARLAEAEETIESLNQKVVALEKTK 676
E A +L K ++L+ + EE +++ N AL+ +
Sbjct: 511 E--ALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSAR 553
Score = 56.0 bits (129), Expect = 1e-07
Identities = 40/228 (17%), Positives = 98/228 (42%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
V D+ L+Q K++ E+ + + ++ + + L N+K E+ +K+ +LN +
Sbjct: 247 VDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLEERLKKKDFELNAL 306
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
++ ++ + L K+L +L +LE + +++ K++ L+ +LE+
Sbjct: 307 NARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERL 366
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEG 559
+E + + + E + +R +EE L K +A++ +
Sbjct: 367 EEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNL 426
Query: 560 VARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVED 703
++LE+ K + + L + +E + + LEK + L ++ +
Sbjct: 427 QRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNE 474
Score = 52.4 bits (120), Expect = 2e-06
Identities = 57/244 (23%), Positives = 110/244 (45%), Gaps = 19/244 (7%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQ-EKIVKQLQHQLNEVQSKA 211
EQ ++ + KA+ ++ ++ SEV R + + ++ + E+ K+L +L E +
Sbjct: 561 EQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAV 620
Query: 212 DEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADE-- 385
+ N + L+ K +L E DL+ +E + + + L K + + L + K+ +E
Sbjct: 621 EAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQ 680
Query: 386 --------EARERATLLGKFRN-----LEHDLDNIREQVEEEAEGKADLQRQLSKANA-- 520
EAR +T L K +N LEH L+ + + + E +DL QL +
Sbjct: 681 SELESSQKEARSLSTELFKLKNAYEESLEH-LETFKRENKNLQEEISDLTEQLGSSGKTI 739
Query: 521 -EAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEV 697
E + R + E+E + LEEA+ L+ + NQ +E+ +LA +
Sbjct: 740 HELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIER---KLAEKD 796
Query: 698 EDLQ 709
E+++
Sbjct: 797 EEME 800
Score = 52.0 bits (119), Expect = 2e-06
Identities = 47/217 (21%), Positives = 90/217 (41%), Gaps = 1/217 (0%)
Frame = +2
Query: 74 EKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAK 253
E+ + + V+ L+ LD + + ++ K+++ LNE++ + ANR +
Sbjct: 800 EQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQV 859
Query: 254 KKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNL- 430
K L D QL++A L K +++ + + + EE R + R L
Sbjct: 860 KSLQSLLKDTQIQLDDAVRANDDL-KENIAIVERRNNLLQAELEELRAVVEQTERSRKLA 918
Query: 431 EHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQAR 610
+ +L E+V+ L Q K +A+ +++ E E V EE +K
Sbjct: 919 DEELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVE-EAVQECRNAEEKAKKAITD 977
Query: 611 LAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
A E ++ LE+ K+ + ++DLQ +D
Sbjct: 978 AAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLD 1014
Score = 50.0 bits (114), Expect = 9e-06
Identities = 39/169 (23%), Positives = 80/169 (47%), Gaps = 2/169 (1%)
Frame = +2
Query: 29 MGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSN-EKAAQEKIVKQLQHQLNEVQS 205
M E+L + A E+ + + DL+ LD +K +++L+ ++ E+++
Sbjct: 981 MAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEN 1040
Query: 206 KADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADE 385
+ + + + +K +L Q EE + +L + L +++ KR A+E
Sbjct: 1041 ELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEE 1100
Query: 386 EARERATLLGKFRNLEHDLDNIREQVEEEAEGKADL-QRQLSKANAEAQ 529
+ T L KFR ++H+LD EAE +AD+ + Q++K A+++
Sbjct: 1101 AEEQANTNLSKFRKVQHELD--------EAEERADIAESQVNKLRAKSR 1141
Score = 49.6 bits (113), Expect = 1e-05
Identities = 47/215 (21%), Positives = 102/215 (47%), Gaps = 8/215 (3%)
Frame = +2
Query: 101 EVNDLRAGLDHLSNEKAAQ-EKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENS 277
E N ++A ++ EK + E+ + ++ +Q+ D R+ N+ KKK+ + +
Sbjct: 780 EFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLN 839
Query: 278 DLLRQLEEAESQVSQLSKIKVSLTTQLEDTK-RL-----ADEEARERATLLGKFRN-LEH 436
++ QL A ++ K SL + L+DT+ +L A+++ +E ++ + N L+
Sbjct: 840 EMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQA 899
Query: 437 DLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLA 616
+L+ +R VE+ + +L + + QL S+ S + + ++++ +LQ +
Sbjct: 900 ELEELRAVVEQTERSRKLADEELIETSERVQLLHSQNTSL-INQKKKMDADLSQLQTEVE 958
Query: 617 EAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
EA + + +K +K A E+L+ E D
Sbjct: 959 EAVQECRNAEEKA---KKAITDAAMMAEELKKEQD 990
Score = 48.0 bits (109), Expect = 4e-05
Identities = 61/254 (24%), Positives = 117/254 (46%), Gaps = 21/254 (8%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+++M QL N++ A+A+K S + D + LD ++ + ++ + N +
Sbjct: 838 LNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLL 897
Query: 200 QSKADEANRTLNDLDAAKKKLS---IENSDLLRQLEEAE-SQVSQLSKIKVSLT---TQL 358
Q++ +E + + ++K IE S+ ++ L S ++Q K+ L+ T++
Sbjct: 898 QAELEELRAVVEQTERSRKLADEELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEV 957
Query: 359 EDTK---RLADEEARERAT---LLGKFRNLEHDLDNIREQVEEEAEGKA-DLQRQLSKAN 517
E+ R A+E+A++ T ++ + E D E++++ E DLQ +L +A
Sbjct: 958 EEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAE 1017
Query: 518 AEAQLWRSKYESEGVARSEELE---EAKRKLQAR----LAEAEETIESLNQKVVALEKTK 676
A K + AR ELE EA++K A + ++E I+ L + K
Sbjct: 1018 QIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNL 1077
Query: 677 QRLATEVEDLQLEV 718
RL V+ LQL+V
Sbjct: 1078 LRLQDLVDKLQLKV 1091
Score = 47.6 bits (108), Expect = 5e-05
Identities = 48/224 (21%), Positives = 101/224 (45%), Gaps = 4/224 (1%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD 214
E L+ L K + + + E++DL L EK+ KQL+ + E+QS +
Sbjct: 706 ESLEHLETFKRENKNLQ----EEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALE 761
Query: 215 EANRTLNDLDAAKKKLSIE----NSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLAD 382
EA +L + + +E +++ R+L E + ++ Q + + + L+ + D
Sbjct: 762 EAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTS---LD 818
Query: 383 EEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGV 562
E R R L + +E DL+ + Q+ A+ Q+Q+ + + + + + + V
Sbjct: 819 AETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLD-DAV 877
Query: 563 ARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATE 694
+++L+E ++ R + +E L V E+++ +LA E
Sbjct: 878 RANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSR-KLADE 920
Score = 43.2 bits (97), Expect = 0.001
Identities = 49/202 (24%), Positives = 88/202 (43%), Gaps = 13/202 (6%)
Frame = +2
Query: 143 EKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQ 322
E A+ ++ +L+ L + +++ E + L K L ++ L +AE + Q
Sbjct: 64 EMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQ 123
Query: 323 LSKIKVSLTTQ-------LEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEG 481
L K K+ L + LED E A L K R LE + ++ ++
Sbjct: 124 LIKNKIQLEAKVKEMNERLED-------EEEMNAELTAKKRKLEDECSELKRDID----- 171
Query: 482 KADLQRQLSKANAEAQLWRSKYE--SEGVARSEE----LEEAKRKLQARLAEAEETIESL 643
DL+ L+K E +K + +E +A +E L + K+ LQ +A + +++
Sbjct: 172 --DLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAE 229
Query: 644 NQKVVALEKTKQRLATEVEDLQ 709
KV L K K +L +V+DL+
Sbjct: 230 EDKVNTLTKAKVKLEQQVDDLE 251
Score = 30.7 bits (66), Expect = 6.2
Identities = 23/86 (26%), Positives = 45/86 (52%), Gaps = 3/86 (3%)
Frame = +2
Query: 455 EQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQAR---LAEAE 625
E+ +E A K + R L +A +++ R + E + V+ +E + + ++QA LA+AE
Sbjct: 60 EREKEMASMKEEFTR-LKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAE 118
Query: 626 ETIESLNQKVVALEKTKQRLATEVED 703
E + L + + LE + + +ED
Sbjct: 119 ERCDQLIKNKIQLEAKVKEMNERLED 144
>M58018-1|AAA62830.1| 1935|Homo sapiens beta-myosin heavy chain
protein.
Length = 1935
Score = 233 bits (571), Expect = 4e-61
Identities = 110/235 (46%), Positives = 167/235 (71%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
V+++GEQ+D L ++K K EK ++++ E++D+ + ++ + KA EK+ + L+ Q+NE
Sbjct: 1200 VAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEH 1259
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
+SKA+E R++NDL + + KL EN +L RQL+E E+ +SQL++ K++ T QLED KR
Sbjct: 1260 RSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQL 1319
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEG 559
+EE + + L ++ HD D +REQ EEE E KA+LQR LSKAN+E WR+KYE++
Sbjct: 1320 EEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDA 1379
Query: 560 VARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
+ R+EELEEAK+KL RL EAEE +E++N K +LEKTK RL E+EDL ++V+R
Sbjct: 1380 IQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVER 1434
Score = 73.7 bits (173), Expect = 7e-13
Identities = 51/237 (21%), Positives = 109/237 (45%), Gaps = 1/237 (0%)
Frame = +2
Query: 14 RFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLN 193
R V + LD + + +A + + + ++N++ L H + A +K VK LQ L
Sbjct: 1592 RVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLK 1651
Query: 194 EVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKR 373
+ Q + D+A R +DL + N+ L +LEE + V Q + + +L +T
Sbjct: 1652 DTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSE 1711
Query: 374 LADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYES 553
+ +L+ + + ++ DL ++ +VEE + + + + KA +A + + +
Sbjct: 1712 RVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKK 1771
Query: 554 EGVARSEELEEAKRKLQARLAEAEETIESLNQ-KVVALEKTKQRLATEVEDLQLEVD 721
E S LE K+ ++ + + + ++ Q + +K Q+L V +L+ E++
Sbjct: 1772 E-QDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELE 1827
Score = 70.5 bits (165), Expect = 6e-12
Identities = 59/235 (25%), Positives = 109/235 (46%), Gaps = 1/235 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+ D+ + D++N L K + + +V+DL L+ + E+ ++L+ L
Sbjct: 1007 LDDLQAEEDKVNTLT----KAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLT 1062
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
Q + LD KK E + L ++E+ ++ SQL K L ++E+ +
Sbjct: 1063 QESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEEL 1122
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKAN-AEAQLWRSKYESE 556
+ E RA + +L +L+ I E++EE A G +Q +++K AE Q R E E
Sbjct: 1123 ESERTARAKVEKLRSDLSRELEEISERLEE-AGGATSVQIEMNKKREAEFQKMRRDLE-E 1180
Query: 557 GVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
+ E A RK A +++ L +++ L++ KQ+L E + +LE+D
Sbjct: 1181 ATLQHEATAAALRKKHA------DSVAELGEQIDNLQRVKQKLEKEKSEFKLELD 1229
Score = 68.5 bits (160), Expect = 3e-11
Identities = 57/227 (25%), Positives = 110/227 (48%), Gaps = 5/227 (2%)
Frame = +2
Query: 23 SDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLR---AGLDHLSNEKAAQEKIVKQLQHQ-L 190
S++ +D L AK EK + ++V +L AGLD + + ++K +++ Q L
Sbjct: 948 SELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQAL 1007
Query: 191 NEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTK 370
+++Q++ D+ +N L AK KL + DL LE+ + L + K L L+ T+
Sbjct: 1008 DDLQAEEDK----VNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQ 1063
Query: 371 RLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYE 550
+ ++ L + + + +L+ + ++E+E + LQ++L + A + + E
Sbjct: 1064 ESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELE 1123
Query: 551 SEGVARSEELEEAKRKLQARLAEAEETIESLNQKV-VALEKTKQRLA 688
SE AR+ ++E+ + L L E E +E V +E K+R A
Sbjct: 1124 SERTARA-KVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREA 1169
Score = 64.9 bits (151), Expect = 3e-10
Identities = 50/231 (21%), Positives = 103/231 (44%), Gaps = 1/231 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+ D+ QL++ K K + + LR + + KA ++++ + ++ +
Sbjct: 1312 LEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQW 1371
Query: 200 QSKAD-EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRL 376
++K + +A + +L+ AKKKL+ + +E ++ S L K K L ++ED
Sbjct: 1372 RTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVD 1431
Query: 377 ADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESE 556
+ A L K RN + L +++ EE Q++ + E ++ YE E
Sbjct: 1432 VERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYE-E 1490
Query: 557 GVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQ 709
+ E + + LQ +++ E + S + + LEK +++L E +LQ
Sbjct: 1491 SLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQ 1541
Score = 59.7 bits (138), Expect = 1e-08
Identities = 46/235 (19%), Positives = 110/235 (46%), Gaps = 1/235 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+SD+ EQL K + EK R Q +E +L++ L+ +E + + Q + N++
Sbjct: 1509 ISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQI 1568
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQV-SQLSKIKVSLTTQLEDTKRL 376
+++ + ++ K+ + D L+ +AE++ ++ ++K + L + +
Sbjct: 1569 KAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQ 1628
Query: 377 ADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESE 556
R A + ++L+ L + + Q+++ DL+ ++ L +++ E E
Sbjct: 1629 LSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELE-E 1687
Query: 557 GVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
A E+ E +++ + L E E ++ L+ + +L K+++ ++ LQ EV+
Sbjct: 1688 LRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVE 1742
Score = 57.2 bits (132), Expect = 6e-08
Identities = 49/225 (21%), Positives = 100/225 (44%), Gaps = 6/225 (2%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+ ++ E+L+ +AK EK R+ E+ ++ L+ + Q ++ K+ + + ++
Sbjct: 1115 IEELEEELESERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKM 1174
Query: 200 QSKADEANRTLNDLDAAKKKLSIEN-SDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRL 376
+ +EA AA +K ++ ++L Q++ + +L K K +L+D
Sbjct: 1175 RRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSN 1234
Query: 377 ADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAE-AQLWRSKYES 553
++ + +A L R LE ++ R + EE DL Q +K E +L R E
Sbjct: 1235 MEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEK 1294
Query: 554 EGVARSEELEEAK----RKLQARLAEAEETIESLNQKVVALEKTK 676
E A +L K ++L+ + EE +++ N AL+ +
Sbjct: 1295 E--ALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSAR 1337
Score = 55.2 bits (127), Expect = 3e-07
Identities = 39/228 (17%), Positives = 98/228 (42%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
V D+ L+Q K++ E+ + + ++ + + L N+K ++ +K+ +LN +
Sbjct: 1031 VDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNAL 1090
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
++ ++ + L K+L +L +LE + +++ K++ L+ +LE+
Sbjct: 1091 NARIEDEQALGSQLQKKLKELQARIEELEEELESERTARAKVEKLRSDLSRELEEISERL 1150
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEG 559
+E + + + E + +R +EE L K +A++ +
Sbjct: 1151 EEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNL 1210
Query: 560 VARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVED 703
++LE+ K + + L + +E + + LEK + L ++ +
Sbjct: 1211 QRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNE 1258
Score = 53.2 bits (122), Expect = 1e-06
Identities = 48/217 (22%), Positives = 90/217 (41%), Gaps = 1/217 (0%)
Frame = +2
Query: 74 EKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAK 253
E+ + + V+ L+ LD + + ++ K+++ LNE++ + ANR +
Sbjct: 1584 EQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQV 1643
Query: 254 KKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNL- 430
K L D QL++A L K +++ + + + EE R + R L
Sbjct: 1644 KSLQSLLKDTQIQLDDAVRANDDL-KENIAIVERRNNLLQAELEELRAVVEQTERSRKLA 1702
Query: 431 EHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQAR 610
E +L E+V+ L Q K +A+ +++ E E V EE +K
Sbjct: 1703 EQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVE-EAVQECRNAEEKAKKAITD 1761
Query: 611 LAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
A E ++ LE+ K+ + ++DLQ +D
Sbjct: 1762 AAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLD 1798
Score = 50.8 bits (116), Expect = 5e-06
Identities = 47/215 (21%), Positives = 104/215 (48%), Gaps = 8/215 (3%)
Frame = +2
Query: 101 EVNDLRAGLDHLSNEKAAQ-EKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENS 277
E N ++A ++ EK + E+ + ++ +Q+ D R+ N+ KKK+ + +
Sbjct: 1564 EFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLN 1623
Query: 278 DLLRQLEEAESQVSQLSKIKVSLTTQLEDTK-RL-----ADEEARERATLLGKFRN-LEH 436
++ QL A ++ K SL + L+DT+ +L A+++ +E ++ + N L+
Sbjct: 1624 EMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQA 1683
Query: 437 DLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLA 616
+L+ +R VE+ + +++L + + QL S+ S + + ++++ +LQ +
Sbjct: 1684 ELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSL-INQKKKMDADLSQLQTEVE 1742
Query: 617 EAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
EA + + +K +K A E+L+ E D
Sbjct: 1743 EAVQECRNAEEKA---KKAITDAAMMAEELKKEQD 1774
Score = 50.0 bits (114), Expect = 9e-06
Identities = 39/169 (23%), Positives = 80/169 (47%), Gaps = 2/169 (1%)
Frame = +2
Query: 29 MGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSN-EKAAQEKIVKQLQHQLNEVQS 205
M E+L + A E+ + + DL+ LD +K +++L+ ++ E+++
Sbjct: 1765 MAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEN 1824
Query: 206 KADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADE 385
+ + + + +K +L Q EE + +L + L +++ KR A+E
Sbjct: 1825 ELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEE 1884
Query: 386 EARERATLLGKFRNLEHDLDNIREQVEEEAEGKADL-QRQLSKANAEAQ 529
+ T L KFR ++H+LD EAE +AD+ + Q++K A+++
Sbjct: 1885 AEEQANTNLSKFRKVQHELD--------EAEERADIAESQVNKLRAKSR 1925
Score = 48.0 bits (109), Expect = 4e-05
Identities = 61/254 (24%), Positives = 117/254 (46%), Gaps = 21/254 (8%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+++M QL N++ A+A+K S + D + LD ++ + ++ + N +
Sbjct: 1622 LNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLL 1681
Query: 200 QSKADEANRTLNDLDAAKKKLS---IENSDLLRQLEEAE-SQVSQLSKIKVSLT---TQL 358
Q++ +E + + ++K IE S+ ++ L S ++Q K+ L+ T++
Sbjct: 1682 QAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEV 1741
Query: 359 EDTK---RLADEEARERAT---LLGKFRNLEHDLDNIREQVEEEAEGKA-DLQRQLSKAN 517
E+ R A+E+A++ T ++ + E D E++++ E DLQ +L +A
Sbjct: 1742 EEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAE 1801
Query: 518 AEAQLWRSKYESEGVARSEELE---EAKRKLQAR----LAEAEETIESLNQKVVALEKTK 676
A K + AR ELE EA++K A + ++E I+ L + K
Sbjct: 1802 QIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNL 1861
Query: 677 QRLATEVEDLQLEV 718
RL V+ LQL+V
Sbjct: 1862 LRLQDLVDKLQLKV 1875
Score = 47.6 bits (108), Expect = 5e-05
Identities = 51/234 (21%), Positives = 103/234 (44%), Gaps = 8/234 (3%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD 214
E L+ L K + + + E++DL L EK+ KQL+ + E+QS +
Sbjct: 1490 ESLEHLETFKRENKNLQ----EEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALE 1545
Query: 215 EANRTLNDLDAAKKKLSIE----NSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLAD 382
EA +L + + +E +++ R+L E + ++ Q + + + L+ + D
Sbjct: 1546 EAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTS---LD 1602
Query: 383 EEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGV 562
E R R L + +E DL+ + Q+ A+ Q+Q+ + + + + + + V
Sbjct: 1603 AETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLD-DAV 1661
Query: 563 ARSEELEE----AKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQL 712
+++L+E +R+ AE EE + Q + + +Q L E +QL
Sbjct: 1662 RANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQL 1715
Score = 43.2 bits (97), Expect = 0.001
Identities = 49/202 (24%), Positives = 88/202 (43%), Gaps = 13/202 (6%)
Frame = +2
Query: 143 EKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQ 322
E A+ ++ +L+ L + +++ E + L K L ++ L +AE + Q
Sbjct: 848 EMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQ 907
Query: 323 LSKIKVSLTTQ-------LEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEG 481
L K K+ L + LED E A L K R LE + ++ ++
Sbjct: 908 LIKNKIQLEAKVKEMNERLED-------EEEMNAELTAKKRKLEDECSELKRDID----- 955
Query: 482 KADLQRQLSKANAEAQLWRSKYE--SEGVARSEE----LEEAKRKLQARLAEAEETIESL 643
DL+ L+K E +K + +E +A +E L + K+ LQ +A + +++
Sbjct: 956 --DLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAE 1013
Query: 644 NQKVVALEKTKQRLATEVEDLQ 709
KV L K K +L +V+DL+
Sbjct: 1014 EDKVNTLTKAKVKLEQQVDDLE 1035
Score = 30.7 bits (66), Expect = 6.2
Identities = 23/86 (26%), Positives = 45/86 (52%), Gaps = 3/86 (3%)
Frame = +2
Query: 455 EQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQAR---LAEAE 625
E+ +E A K + R L +A +++ R + E + V+ +E + + ++QA LA+AE
Sbjct: 844 EREKEMASMKEEFTR-LKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAE 902
Query: 626 ETIESLNQKVVALEKTKQRLATEVED 703
E + L + + LE + + +ED
Sbjct: 903 ERCDQLIKNKIQLEAKVKEMNERLED 928
>M57965-1|AAA51837.1| 1935|Homo sapiens beta-myosin heavy chain
protein.
Length = 1935
Score = 233 bits (571), Expect = 4e-61
Identities = 110/235 (46%), Positives = 167/235 (71%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
V+++GEQ+D L ++K K EK ++++ E++D+ + ++ + KA EK+ + L+ Q+NE
Sbjct: 1200 VAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEH 1259
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
+SKA+E R++NDL + + KL EN +L RQL+E E+ +SQL++ K++ T QLED KR
Sbjct: 1260 RSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQL 1319
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEG 559
+EE + + L ++ HD D +REQ EEE E KA+LQR LSKAN+E WR+KYE++
Sbjct: 1320 EEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDA 1379
Query: 560 VARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
+ R+EELEEAK+KL RL EAEE +E++N K +LEKTK RL E+EDL ++V+R
Sbjct: 1380 IQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVER 1434
Score = 73.7 bits (173), Expect = 7e-13
Identities = 51/237 (21%), Positives = 109/237 (45%), Gaps = 1/237 (0%)
Frame = +2
Query: 14 RFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLN 193
R V + LD + + +A + + + ++N++ L H + A +K VK LQ L
Sbjct: 1592 RVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLK 1651
Query: 194 EVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKR 373
+ Q + D+A R +DL + N+ L +LEE + V Q + + +L +T
Sbjct: 1652 DTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSE 1711
Query: 374 LADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYES 553
+ +L+ + + ++ DL ++ +VEE + + + + KA +A + + +
Sbjct: 1712 RVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKK 1771
Query: 554 EGVARSEELEEAKRKLQARLAEAEETIESLNQ-KVVALEKTKQRLATEVEDLQLEVD 721
E S LE K+ ++ + + + ++ Q + +K Q+L V +L+ E++
Sbjct: 1772 E-QDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELE 1827
Score = 70.5 bits (165), Expect = 6e-12
Identities = 59/235 (25%), Positives = 109/235 (46%), Gaps = 1/235 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+ D+ + D++N L K + + +V+DL L+ + E+ ++L+ L
Sbjct: 1007 LDDLQAEEDKVNTLT----KAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLT 1062
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
Q + LD KK E + L ++E+ ++ SQL K L ++E+ +
Sbjct: 1063 QESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEEL 1122
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKAN-AEAQLWRSKYESE 556
+ E RA + +L +L+ I E++EE A G +Q +++K AE Q R E E
Sbjct: 1123 ESERTARAKVEKLRSDLSRELEEISERLEE-AGGATSVQIEMNKKREAEFQKMRRDLE-E 1180
Query: 557 GVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
+ E A RK A +++ L +++ L++ KQ+L E + +LE+D
Sbjct: 1181 ATLQHEATAAALRKKHA------DSVAELGEQIDNLQRVKQKLEKEKSEFKLELD 1229
Score = 68.5 bits (160), Expect = 3e-11
Identities = 57/227 (25%), Positives = 110/227 (48%), Gaps = 5/227 (2%)
Frame = +2
Query: 23 SDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLR---AGLDHLSNEKAAQEKIVKQLQHQ-L 190
S++ +D L AK EK + ++V +L AGLD + + ++K +++ Q L
Sbjct: 948 SELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQAL 1007
Query: 191 NEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTK 370
+++Q++ D+ +N L AK KL + DL LE+ + L + K L L+ T+
Sbjct: 1008 DDLQAEEDK----VNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQ 1063
Query: 371 RLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYE 550
+ ++ L + + + +L+ + ++E+E + LQ++L + A + + E
Sbjct: 1064 ESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELE 1123
Query: 551 SEGVARSEELEEAKRKLQARLAEAEETIESLNQKV-VALEKTKQRLA 688
SE AR+ ++E+ + L L E E +E V +E K+R A
Sbjct: 1124 SERTARA-KVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREA 1169
Score = 64.9 bits (151), Expect = 3e-10
Identities = 50/231 (21%), Positives = 103/231 (44%), Gaps = 1/231 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+ D+ QL++ K K + + LR + + KA ++++ + ++ +
Sbjct: 1312 LEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQW 1371
Query: 200 QSKAD-EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRL 376
++K + +A + +L+ AKKKL+ + +E ++ S L K K L ++ED
Sbjct: 1372 RTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVD 1431
Query: 377 ADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESE 556
+ A L K RN + L +++ EE Q++ + E ++ YE E
Sbjct: 1432 VERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYE-E 1490
Query: 557 GVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQ 709
+ E + + LQ +++ E + S + + LEK +++L E +LQ
Sbjct: 1491 SLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQ 1541
Score = 59.7 bits (138), Expect = 1e-08
Identities = 46/235 (19%), Positives = 110/235 (46%), Gaps = 1/235 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+SD+ EQL K + EK R Q +E +L++ L+ +E + + Q + N++
Sbjct: 1509 ISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQI 1568
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQV-SQLSKIKVSLTTQLEDTKRL 376
+++ + ++ K+ + D L+ +AE++ ++ ++K + L + +
Sbjct: 1569 KAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQ 1628
Query: 377 ADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESE 556
R A + ++L+ L + + Q+++ DL+ ++ L +++ E E
Sbjct: 1629 LSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELE-E 1687
Query: 557 GVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
A E+ E +++ + L E E ++ L+ + +L K+++ ++ LQ EV+
Sbjct: 1688 LRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVE 1742
Score = 57.2 bits (132), Expect = 6e-08
Identities = 49/225 (21%), Positives = 100/225 (44%), Gaps = 6/225 (2%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+ ++ E+L+ +AK EK R+ E+ ++ L+ + Q ++ K+ + + ++
Sbjct: 1115 IEELEEELESERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKM 1174
Query: 200 QSKADEANRTLNDLDAAKKKLSIEN-SDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRL 376
+ +EA AA +K ++ ++L Q++ + +L K K +L+D
Sbjct: 1175 RRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSN 1234
Query: 377 ADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAE-AQLWRSKYES 553
++ + +A L R LE ++ R + EE DL Q +K E +L R E
Sbjct: 1235 MEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEK 1294
Query: 554 EGVARSEELEEAK----RKLQARLAEAEETIESLNQKVVALEKTK 676
E A +L K ++L+ + EE +++ N AL+ +
Sbjct: 1295 E--ALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSAR 1337
Score = 55.2 bits (127), Expect = 3e-07
Identities = 39/228 (17%), Positives = 98/228 (42%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
V D+ L+Q K++ E+ + + ++ + + L N+K ++ +K+ +LN +
Sbjct: 1031 VDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNAL 1090
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
++ ++ + L K+L +L +LE + +++ K++ L+ +LE+
Sbjct: 1091 NARIEDEQALGSQLQKKLKELQARIEELEEELESERTARAKVEKLRSDLSRELEEISERL 1150
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEG 559
+E + + + E + +R +EE L K +A++ +
Sbjct: 1151 EEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNL 1210
Query: 560 VARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVED 703
++LE+ K + + L + +E + + LEK + L ++ +
Sbjct: 1211 QRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNE 1258
Score = 53.2 bits (122), Expect = 1e-06
Identities = 48/217 (22%), Positives = 90/217 (41%), Gaps = 1/217 (0%)
Frame = +2
Query: 74 EKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAK 253
E+ + + V+ L+ LD + + ++ K+++ LNE++ + ANR +
Sbjct: 1584 EQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQV 1643
Query: 254 KKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNL- 430
K L D QL++A L K +++ + + + EE R + R L
Sbjct: 1644 KSLQSLLKDTQIQLDDAVRANDDL-KENIAIVERRNNLLQAELEELRAVVEQTERSRKLA 1702
Query: 431 EHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQAR 610
E +L E+V+ L Q K +A+ +++ E E V EE +K
Sbjct: 1703 EQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVE-EAVQECRNAEEKAKKAITD 1761
Query: 611 LAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
A E ++ LE+ K+ + ++DLQ +D
Sbjct: 1762 AAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLD 1798
Score = 50.8 bits (116), Expect = 5e-06
Identities = 47/215 (21%), Positives = 104/215 (48%), Gaps = 8/215 (3%)
Frame = +2
Query: 101 EVNDLRAGLDHLSNEKAAQ-EKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENS 277
E N ++A ++ EK + E+ + ++ +Q+ D R+ N+ KKK+ + +
Sbjct: 1564 EFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLN 1623
Query: 278 DLLRQLEEAESQVSQLSKIKVSLTTQLEDTK-RL-----ADEEARERATLLGKFRN-LEH 436
++ QL A ++ K SL + L+DT+ +L A+++ +E ++ + N L+
Sbjct: 1624 EMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQA 1683
Query: 437 DLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLA 616
+L+ +R VE+ + +++L + + QL S+ S + + ++++ +LQ +
Sbjct: 1684 ELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSL-INQKKKMDADLSQLQTEVE 1742
Query: 617 EAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
EA + + +K +K A E+L+ E D
Sbjct: 1743 EAVQECRNAEEKA---KKAITDAAMMAEELKKEQD 1774
Score = 50.0 bits (114), Expect = 9e-06
Identities = 39/169 (23%), Positives = 80/169 (47%), Gaps = 2/169 (1%)
Frame = +2
Query: 29 MGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSN-EKAAQEKIVKQLQHQLNEVQS 205
M E+L + A E+ + + DL+ LD +K +++L+ ++ E+++
Sbjct: 1765 MAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEN 1824
Query: 206 KADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADE 385
+ + + + +K +L Q EE + +L + L +++ KR A+E
Sbjct: 1825 ELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEE 1884
Query: 386 EARERATLLGKFRNLEHDLDNIREQVEEEAEGKADL-QRQLSKANAEAQ 529
+ T L KFR ++H+LD EAE +AD+ + Q++K A+++
Sbjct: 1885 AEEQANTNLSKFRKVQHELD--------EAEERADIAESQVNKLRAKSR 1925
Score = 48.0 bits (109), Expect = 4e-05
Identities = 61/254 (24%), Positives = 117/254 (46%), Gaps = 21/254 (8%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+++M QL N++ A+A+K S + D + LD ++ + ++ + N +
Sbjct: 1622 LNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLL 1681
Query: 200 QSKADEANRTLNDLDAAKKKLS---IENSDLLRQLEEAE-SQVSQLSKIKVSLT---TQL 358
Q++ +E + + ++K IE S+ ++ L S ++Q K+ L+ T++
Sbjct: 1682 QAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEV 1741
Query: 359 EDTK---RLADEEARERAT---LLGKFRNLEHDLDNIREQVEEEAEGKA-DLQRQLSKAN 517
E+ R A+E+A++ T ++ + E D E++++ E DLQ +L +A
Sbjct: 1742 EEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAE 1801
Query: 518 AEAQLWRSKYESEGVARSEELE---EAKRKLQAR----LAEAEETIESLNQKVVALEKTK 676
A K + AR ELE EA++K A + ++E I+ L + K
Sbjct: 1802 QIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNL 1861
Query: 677 QRLATEVEDLQLEV 718
RL V+ LQL+V
Sbjct: 1862 LRLQDLVDKLQLKV 1875
Score = 47.6 bits (108), Expect = 5e-05
Identities = 51/234 (21%), Positives = 103/234 (44%), Gaps = 8/234 (3%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD 214
E L+ L K + + + E++DL L EK+ KQL+ + E+QS +
Sbjct: 1490 ESLEHLETFKRENKNLQ----EEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALE 1545
Query: 215 EANRTLNDLDAAKKKLSIE----NSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLAD 382
EA +L + + +E +++ R+L E + ++ Q + + + L+ + D
Sbjct: 1546 EAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTS---LD 1602
Query: 383 EEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGV 562
E R R L + +E DL+ + Q+ A+ Q+Q+ + + + + + + V
Sbjct: 1603 AETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLD-DAV 1661
Query: 563 ARSEELEE----AKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQL 712
+++L+E +R+ AE EE + Q + + +Q L E +QL
Sbjct: 1662 RANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQL 1715
Score = 43.2 bits (97), Expect = 0.001
Identities = 49/202 (24%), Positives = 88/202 (43%), Gaps = 13/202 (6%)
Frame = +2
Query: 143 EKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQ 322
E A+ ++ +L+ L + +++ E + L K L ++ L +AE + Q
Sbjct: 848 EMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQ 907
Query: 323 LSKIKVSLTTQ-------LEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEG 481
L K K+ L + LED E A L K R LE + ++ ++
Sbjct: 908 LIKNKIQLEAKVKEMNERLED-------EEEMNAELTAKKRKLEDECSELKRDID----- 955
Query: 482 KADLQRQLSKANAEAQLWRSKYE--SEGVARSEE----LEEAKRKLQARLAEAEETIESL 643
DL+ L+K E +K + +E +A +E L + K+ LQ +A + +++
Sbjct: 956 --DLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAE 1013
Query: 644 NQKVVALEKTKQRLATEVEDLQ 709
KV L K K +L +V+DL+
Sbjct: 1014 EDKVNTLTKAKVKLEQQVDDLE 1035
Score = 30.7 bits (66), Expect = 6.2
Identities = 23/86 (26%), Positives = 45/86 (52%), Gaps = 3/86 (3%)
Frame = +2
Query: 455 EQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQAR---LAEAE 625
E+ +E A K + R L +A +++ R + E + V+ +E + + ++QA LA+AE
Sbjct: 844 EREKEMASMKEEFTR-LKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAE 902
Query: 626 ETIESLNQKVVALEKTKQRLATEVED 703
E + L + + LE + + +ED
Sbjct: 903 ERCDQLIKNKIQLEAKVKEMNERLED 928
>EF560725-1|ABQ59035.1| 1934|Homo sapiens MYH7 protein protein.
Length = 1934
Score = 233 bits (571), Expect = 4e-61
Identities = 110/235 (46%), Positives = 167/235 (71%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
V+++GEQ+D L ++K K EK ++++ E++D+ + ++ + KA EK+ + L+ Q+NE
Sbjct: 1199 VAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEH 1258
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
+SKA+E R++NDL + + KL EN +L RQL+E E+ +SQL++ K++ T QLED KR
Sbjct: 1259 RSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQL 1318
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEG 559
+EE + + L ++ HD D +REQ EEE E KA+LQR LSKAN+E WR+KYE++
Sbjct: 1319 EEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDA 1378
Query: 560 VARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
+ R+EELEEAK+KL RL EAEE +E++N K +LEKTK RL E+EDL ++V+R
Sbjct: 1379 IQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVER 1433
Score = 74.5 bits (175), Expect = 4e-13
Identities = 51/237 (21%), Positives = 110/237 (46%), Gaps = 1/237 (0%)
Frame = +2
Query: 14 RFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLN 193
R V + LD + + +A + + + ++N++ L H + A +K VK LQ L
Sbjct: 1591 RVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLK 1650
Query: 194 EVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKR 373
+ Q + D+A R +DL + N+ L +LEE + V Q + + + +L +T
Sbjct: 1651 DTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLVEQELIETSE 1710
Query: 374 LADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYES 553
+ +L+ + + ++ DL ++ +VEE + + + + KA +A + + +
Sbjct: 1711 RVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKK 1770
Query: 554 EGVARSEELEEAKRKLQARLAEAEETIESLNQ-KVVALEKTKQRLATEVEDLQLEVD 721
E S LE K+ ++ + + + ++ Q + +K Q+L V +L+ E++
Sbjct: 1771 E-QDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELE 1826
Score = 70.1 bits (164), Expect = 8e-12
Identities = 59/235 (25%), Positives = 109/235 (46%), Gaps = 1/235 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+ D+ + D++N L K + + +V+DL L+ + E+ ++L+ L
Sbjct: 1006 LDDLQAEEDKVNTLT----KAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLT 1061
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
Q + LD KK E + L ++E+ ++ SQL K L ++E+ +
Sbjct: 1062 QESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEEL 1121
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKAN-AEAQLWRSKYESE 556
+ E RA + +L +L+ I E++EE A G +Q +++K AE Q R E E
Sbjct: 1122 EAERTARAKVEKLRSDLSRELEEISERLEE-AGGATSVQIEMNKKREAEFQKMRRDLE-E 1179
Query: 557 GVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
+ E A RK A +++ L +++ L++ KQ+L E + +LE+D
Sbjct: 1180 ATLQHEATAAALRKKHA------DSVAELGEQIDNLQRVKQKLEKEKSEFKLELD 1228
Score = 64.9 bits (151), Expect = 3e-10
Identities = 50/231 (21%), Positives = 103/231 (44%), Gaps = 1/231 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+ D+ QL++ K K + + LR + + KA ++++ + ++ +
Sbjct: 1311 LEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQW 1370
Query: 200 QSKAD-EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRL 376
++K + +A + +L+ AKKKL+ + +E ++ S L K K L ++ED
Sbjct: 1371 RTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVD 1430
Query: 377 ADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESE 556
+ A L K RN + L +++ EE Q++ + E ++ YE E
Sbjct: 1431 VERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYE-E 1489
Query: 557 GVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQ 709
+ E + + LQ +++ E + S + + LEK +++L E +LQ
Sbjct: 1490 SLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQ 1540
Score = 60.5 bits (140), Expect = 7e-09
Identities = 46/235 (19%), Positives = 111/235 (47%), Gaps = 1/235 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+SD+ EQL K + EK R Q +E +L++ L+ +E + + Q + N++
Sbjct: 1508 ISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQI 1567
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQV-SQLSKIKVSLTTQLEDTKRL 376
+++ + ++ K+ + D L+ +AE++ ++ ++K + L + +
Sbjct: 1568 KAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQ 1627
Query: 377 ADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESE 556
R A + ++L+ L + + Q+++ DL+ ++ L +++ E E
Sbjct: 1628 LSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELE-E 1686
Query: 557 GVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
A E+ E +++ ++ L E E ++ L+ + +L K+++ ++ LQ EV+
Sbjct: 1687 LRAVVEQTERSRKLVEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVE 1741
Score = 56.8 bits (131), Expect = 8e-08
Identities = 49/225 (21%), Positives = 100/225 (44%), Gaps = 6/225 (2%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+ ++ E+L+ +AK EK R+ E+ ++ L+ + Q ++ K+ + + ++
Sbjct: 1114 IEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKM 1173
Query: 200 QSKADEANRTLNDLDAAKKKLSIEN-SDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRL 376
+ +EA AA +K ++ ++L Q++ + +L K K +L+D
Sbjct: 1174 RRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSN 1233
Query: 377 ADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAE-AQLWRSKYES 553
++ + +A L R LE ++ R + EE DL Q +K E +L R E
Sbjct: 1234 MEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEK 1293
Query: 554 EGVARSEELEEAK----RKLQARLAEAEETIESLNQKVVALEKTK 676
E A +L K ++L+ + EE +++ N AL+ +
Sbjct: 1294 E--ALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSAR 1336
Score = 54.8 bits (126), Expect = 3e-07
Identities = 39/228 (17%), Positives = 98/228 (42%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
V D+ L+Q K++ E+ + + ++ + + L N+K ++ +K+ +LN +
Sbjct: 1030 VDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNAL 1089
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
++ ++ + L K+L +L +LE + +++ K++ L+ +LE+
Sbjct: 1090 NARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERL 1149
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEG 559
+E + + + E + +R +EE L K +A++ +
Sbjct: 1150 EEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNL 1209
Query: 560 VARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVED 703
++LE+ K + + L + +E + + LEK + L ++ +
Sbjct: 1210 QRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNE 1257
Score = 53.2 bits (122), Expect = 1e-06
Identities = 45/223 (20%), Positives = 96/223 (43%), Gaps = 7/223 (3%)
Frame = +2
Query: 74 EKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANR-------TL 232
E+ + + V+ L+ LD + + ++ K+++ LNE++ + ANR +
Sbjct: 1583 EQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQV 1642
Query: 233 NDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLL 412
L + K I+ D +R ++ + ++ + + L +LE+ + + ++ R R
Sbjct: 1643 KSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSR---- 1698
Query: 413 GKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAK 592
+ +E +L E+V+ L Q K +A+ +++ E E V EE
Sbjct: 1699 ---KLVEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVE-EAVQECRNAEEKA 1754
Query: 593 RKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
+K A E ++ LE+ K+ + ++DLQ +D
Sbjct: 1755 KKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLD 1797
Score = 52.4 bits (120), Expect = 2e-06
Identities = 57/244 (23%), Positives = 110/244 (45%), Gaps = 19/244 (7%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQ-EKIVKQLQHQLNEVQSKA 211
EQ ++ + KA+ ++ ++ SEV R + + ++ + E+ K+L +L E +
Sbjct: 1344 EQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAV 1403
Query: 212 DEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADE-- 385
+ N + L+ K +L E DL+ +E + + + L K + + L + K+ +E
Sbjct: 1404 EAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQ 1463
Query: 386 --------EARERATLLGKFRN-----LEHDLDNIREQVEEEAEGKADLQRQLSKANA-- 520
EAR +T L K +N LEH L+ + + + E +DL QL +
Sbjct: 1464 SELESSQKEARSLSTELFKLKNAYEESLEH-LETFKRENKNLQEEISDLTEQLGSSGKTI 1522
Query: 521 -EAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEV 697
E + R + E+E + LEEA+ L+ + NQ +E+ +LA +
Sbjct: 1523 HELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIER---KLAEKD 1579
Query: 698 EDLQ 709
E+++
Sbjct: 1580 EEME 1583
Score = 51.6 bits (118), Expect = 3e-06
Identities = 47/215 (21%), Positives = 105/215 (48%), Gaps = 8/215 (3%)
Frame = +2
Query: 101 EVNDLRAGLDHLSNEKAAQ-EKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENS 277
E N ++A ++ EK + E+ + ++ +Q+ D R+ N+ KKK+ + +
Sbjct: 1563 EFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLN 1622
Query: 278 DLLRQLEEAESQVSQLSKIKVSLTTQLEDTK-RL-----ADEEARERATLLGKFRN-LEH 436
++ QL A ++ K SL + L+DT+ +L A+++ +E ++ + N L+
Sbjct: 1623 EMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQA 1682
Query: 437 DLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLA 616
+L+ +R VE+ + ++++L + + QL S+ S + + ++++ +LQ +
Sbjct: 1683 ELEELRAVVEQTERSRKLVEQELIETSERVQLLHSQNTSL-INQKKKMDADLSQLQTEVE 1741
Query: 617 EAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
EA + + +K +K A E+L+ E D
Sbjct: 1742 EAVQECRNAEEKA---KKAITDAAMMAEELKKEQD 1773
Score = 50.0 bits (114), Expect = 9e-06
Identities = 39/169 (23%), Positives = 80/169 (47%), Gaps = 2/169 (1%)
Frame = +2
Query: 29 MGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSN-EKAAQEKIVKQLQHQLNEVQS 205
M E+L + A E+ + + DL+ LD +K +++L+ ++ E+++
Sbjct: 1764 MAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEN 1823
Query: 206 KADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADE 385
+ + + + +K +L Q EE + +L + L +++ KR A+E
Sbjct: 1824 ELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEE 1883
Query: 386 EARERATLLGKFRNLEHDLDNIREQVEEEAEGKADL-QRQLSKANAEAQ 529
+ T L KFR ++H+LD EAE +AD+ + Q++K A+++
Sbjct: 1884 AEEQANTNLSKFRKVQHELD--------EAEERADIAESQVNKLRAKSR 1924
Score = 48.8 bits (111), Expect = 2e-05
Identities = 61/254 (24%), Positives = 118/254 (46%), Gaps = 21/254 (8%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+++M QL N++ A+A+K S + D + LD ++ + ++ + N +
Sbjct: 1621 LNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLL 1680
Query: 200 QSKADEANRTLNDLDAAKKKLS---IENSDLLRQLEEAE-SQVSQLSKIKVSLT---TQL 358
Q++ +E + + ++K + IE S+ ++ L S ++Q K+ L+ T++
Sbjct: 1681 QAELEELRAVVEQTERSRKLVEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEV 1740
Query: 359 EDTK---RLADEEARERAT---LLGKFRNLEHDLDNIREQVEEEAEGKA-DLQRQLSKAN 517
E+ R A+E+A++ T ++ + E D E++++ E DLQ +L +A
Sbjct: 1741 EEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAE 1800
Query: 518 AEAQLWRSKYESEGVARSEELE---EAKRKLQAR----LAEAEETIESLNQKVVALEKTK 676
A K + AR ELE EA++K A + ++E I+ L + K
Sbjct: 1801 QIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNL 1860
Query: 677 QRLATEVEDLQLEV 718
RL V+ LQL+V
Sbjct: 1861 LRLQDLVDKLQLKV 1874
Score = 48.0 bits (109), Expect = 4e-05
Identities = 46/225 (20%), Positives = 101/225 (44%), Gaps = 4/225 (1%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD 214
E L+ L K + + + E++DL L EK+ KQL+ + E+QS +
Sbjct: 1489 ESLEHLETFKRENKNLQ----EEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALE 1544
Query: 215 EANRTLNDLDAAKKKLSIE----NSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLAD 382
EA +L + + +E +++ R+L E + ++ Q + + + L+ + D
Sbjct: 1545 EAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTS---LD 1601
Query: 383 EEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGV 562
E R R L + +E DL+ + Q+ A+ Q+Q+ + + + + + + V
Sbjct: 1602 AETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLD-DAV 1660
Query: 563 ARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEV 697
+++L+E ++ R + +E L V E++++ + E+
Sbjct: 1661 RANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLVEQEL 1705
Score = 43.2 bits (97), Expect = 0.001
Identities = 49/202 (24%), Positives = 88/202 (43%), Gaps = 13/202 (6%)
Frame = +2
Query: 143 EKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQ 322
E A+ ++ +L+ L + +++ E + L K L ++ L +AE + Q
Sbjct: 847 EMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQ 906
Query: 323 LSKIKVSLTTQ-------LEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEG 481
L K K+ L + LED E A L K R LE + ++ ++
Sbjct: 907 LIKNKIQLEAKVKEMNERLED-------EEEMNAELTAKKRKLEDECSELKRDID----- 954
Query: 482 KADLQRQLSKANAEAQLWRSKYE--SEGVARSEE----LEEAKRKLQARLAEAEETIESL 643
DL+ L+K E +K + +E +A +E L + K+ LQ +A + +++
Sbjct: 955 --DLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAE 1012
Query: 644 NQKVVALEKTKQRLATEVEDLQ 709
KV L K K +L +V+DL+
Sbjct: 1013 EDKVNTLTKAKVKLEQQVDDLE 1034
Score = 30.7 bits (66), Expect = 6.2
Identities = 23/86 (26%), Positives = 45/86 (52%), Gaps = 3/86 (3%)
Frame = +2
Query: 455 EQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQAR---LAEAE 625
E+ +E A K + R L +A +++ R + E + V+ +E + + ++QA LA+AE
Sbjct: 843 EREKEMASMKEEFTR-LKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAE 901
Query: 626 ETIESLNQKVVALEKTKQRLATEVED 703
E + L + + LE + + +ED
Sbjct: 902 ERCDQLIKNKIQLEAKVKEMNERLED 927
>EF179180-1|ABN05283.1| 1935|Homo sapiens myosin, heavy chain 7,
cardiac muscle, beta protein.
Length = 1935
Score = 233 bits (571), Expect = 4e-61
Identities = 110/235 (46%), Positives = 167/235 (71%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
V+++GEQ+D L ++K K EK ++++ E++D+ + ++ + KA EK+ + L+ Q+NE
Sbjct: 1200 VAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEH 1259
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
+SKA+E R++NDL + + KL EN +L RQL+E E+ +SQL++ K++ T QLED KR
Sbjct: 1260 RSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQL 1319
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEG 559
+EE + + L ++ HD D +REQ EEE E KA+LQR LSKAN+E WR+KYE++
Sbjct: 1320 EEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDA 1379
Query: 560 VARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
+ R+EELEEAK+KL RL EAEE +E++N K +LEKTK RL E+EDL ++V+R
Sbjct: 1380 IQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVER 1434
Score = 73.7 bits (173), Expect = 7e-13
Identities = 51/237 (21%), Positives = 109/237 (45%), Gaps = 1/237 (0%)
Frame = +2
Query: 14 RFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLN 193
R V + LD + + +A + + + ++N++ L H + A +K VK LQ L
Sbjct: 1592 RVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLK 1651
Query: 194 EVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKR 373
+ Q + D+A R +DL + N+ L +LEE + V Q + + +L +T
Sbjct: 1652 DTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSE 1711
Query: 374 LADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYES 553
+ +L+ + + ++ DL ++ +VEE + + + + KA +A + + +
Sbjct: 1712 RVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKK 1771
Query: 554 EGVARSEELEEAKRKLQARLAEAEETIESLNQ-KVVALEKTKQRLATEVEDLQLEVD 721
E S LE K+ ++ + + + ++ Q + +K Q+L V +L+ E++
Sbjct: 1772 E-QDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELE 1827
Score = 70.1 bits (164), Expect = 8e-12
Identities = 59/235 (25%), Positives = 109/235 (46%), Gaps = 1/235 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+ D+ + D++N L K + + +V+DL L+ + E+ ++L+ L
Sbjct: 1007 LDDLQAEEDKVNTLT----KAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLT 1062
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
Q + LD KK E + L ++E+ ++ SQL K L ++E+ +
Sbjct: 1063 QESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEEL 1122
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKAN-AEAQLWRSKYESE 556
+ E RA + +L +L+ I E++EE A G +Q +++K AE Q R E E
Sbjct: 1123 EAERTARAKVEKLRSDLSRELEEISERLEE-AGGATSVQIEMNKKREAEFQKMRRDLE-E 1180
Query: 557 GVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
+ E A RK A +++ L +++ L++ KQ+L E + +LE+D
Sbjct: 1181 ATLQHEATAAALRKKHA------DSVAELGEQIDNLQRVKQKLEKEKSEFKLELD 1229
Score = 64.9 bits (151), Expect = 3e-10
Identities = 50/231 (21%), Positives = 103/231 (44%), Gaps = 1/231 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+ D+ QL++ K K + + LR + + KA ++++ + ++ +
Sbjct: 1312 LEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQW 1371
Query: 200 QSKAD-EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRL 376
++K + +A + +L+ AKKKL+ + +E ++ S L K K L ++ED
Sbjct: 1372 RTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVD 1431
Query: 377 ADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESE 556
+ A L K RN + L +++ EE Q++ + E ++ YE E
Sbjct: 1432 VERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYE-E 1490
Query: 557 GVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQ 709
+ E + + LQ +++ E + S + + LEK +++L E +LQ
Sbjct: 1491 SLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQ 1541
Score = 59.7 bits (138), Expect = 1e-08
Identities = 46/235 (19%), Positives = 110/235 (46%), Gaps = 1/235 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+SD+ EQL K + EK R Q +E +L++ L+ +E + + Q + N++
Sbjct: 1509 ISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQI 1568
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQV-SQLSKIKVSLTTQLEDTKRL 376
+++ + ++ K+ + D L+ +AE++ ++ ++K + L + +
Sbjct: 1569 KAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQ 1628
Query: 377 ADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESE 556
R A + ++L+ L + + Q+++ DL+ ++ L +++ E E
Sbjct: 1629 LSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELE-E 1687
Query: 557 GVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
A E+ E +++ + L E E ++ L+ + +L K+++ ++ LQ EV+
Sbjct: 1688 LRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVE 1742
Score = 56.8 bits (131), Expect = 8e-08
Identities = 49/225 (21%), Positives = 100/225 (44%), Gaps = 6/225 (2%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+ ++ E+L+ +AK EK R+ E+ ++ L+ + Q ++ K+ + + ++
Sbjct: 1115 IEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKM 1174
Query: 200 QSKADEANRTLNDLDAAKKKLSIEN-SDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRL 376
+ +EA AA +K ++ ++L Q++ + +L K K +L+D
Sbjct: 1175 RRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSN 1234
Query: 377 ADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAE-AQLWRSKYES 553
++ + +A L R LE ++ R + EE DL Q +K E +L R E
Sbjct: 1235 MEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEK 1294
Query: 554 EGVARSEELEEAK----RKLQARLAEAEETIESLNQKVVALEKTK 676
E A +L K ++L+ + EE +++ N AL+ +
Sbjct: 1295 E--ALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSAR 1337
Score = 54.8 bits (126), Expect = 3e-07
Identities = 39/228 (17%), Positives = 98/228 (42%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
V D+ L+Q K++ E+ + + ++ + + L N+K ++ +K+ +LN +
Sbjct: 1031 VDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNAL 1090
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
++ ++ + L K+L +L +LE + +++ K++ L+ +LE+
Sbjct: 1091 NARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERL 1150
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEG 559
+E + + + E + +R +EE L K +A++ +
Sbjct: 1151 EEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNL 1210
Query: 560 VARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVED 703
++LE+ K + + L + +E + + LEK + L ++ +
Sbjct: 1211 QRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNE 1258
Score = 53.2 bits (122), Expect = 1e-06
Identities = 48/217 (22%), Positives = 90/217 (41%), Gaps = 1/217 (0%)
Frame = +2
Query: 74 EKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAK 253
E+ + + V+ L+ LD + + ++ K+++ LNE++ + ANR +
Sbjct: 1584 EQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQV 1643
Query: 254 KKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNL- 430
K L D QL++A L K +++ + + + EE R + R L
Sbjct: 1644 KSLQSLLKDTQIQLDDAVRANDDL-KENIAIVERRNNLLQAELEELRAVVEQTERSRKLA 1702
Query: 431 EHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQAR 610
E +L E+V+ L Q K +A+ +++ E E V EE +K
Sbjct: 1703 EQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVE-EAVQECRNAEEKAKKAITD 1761
Query: 611 LAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
A E ++ LE+ K+ + ++DLQ +D
Sbjct: 1762 AAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLD 1798
Score = 50.8 bits (116), Expect = 5e-06
Identities = 47/215 (21%), Positives = 104/215 (48%), Gaps = 8/215 (3%)
Frame = +2
Query: 101 EVNDLRAGLDHLSNEKAAQ-EKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENS 277
E N ++A ++ EK + E+ + ++ +Q+ D R+ N+ KKK+ + +
Sbjct: 1564 EFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLN 1623
Query: 278 DLLRQLEEAESQVSQLSKIKVSLTTQLEDTK-RL-----ADEEARERATLLGKFRN-LEH 436
++ QL A ++ K SL + L+DT+ +L A+++ +E ++ + N L+
Sbjct: 1624 EMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQA 1683
Query: 437 DLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLA 616
+L+ +R VE+ + +++L + + QL S+ S + + ++++ +LQ +
Sbjct: 1684 ELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSL-INQKKKMDADLSQLQTEVE 1742
Query: 617 EAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
EA + + +K +K A E+L+ E D
Sbjct: 1743 EAVQECRNAEEKA---KKAITDAAMMAEELKKEQD 1774
Score = 50.0 bits (114), Expect = 9e-06
Identities = 39/169 (23%), Positives = 80/169 (47%), Gaps = 2/169 (1%)
Frame = +2
Query: 29 MGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSN-EKAAQEKIVKQLQHQLNEVQS 205
M E+L + A E+ + + DL+ LD +K +++L+ ++ E+++
Sbjct: 1765 MAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEN 1824
Query: 206 KADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADE 385
+ + + + +K +L Q EE + +L + L +++ KR A+E
Sbjct: 1825 ELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEE 1884
Query: 386 EARERATLLGKFRNLEHDLDNIREQVEEEAEGKADL-QRQLSKANAEAQ 529
+ T L KFR ++H+LD EAE +AD+ + Q++K A+++
Sbjct: 1885 AEEQANTNLSKFRKVQHELD--------EAEERADIAESQVNKLRAKSR 1925
Score = 48.0 bits (109), Expect = 4e-05
Identities = 61/254 (24%), Positives = 117/254 (46%), Gaps = 21/254 (8%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+++M QL N++ A+A+K S + D + LD ++ + ++ + N +
Sbjct: 1622 LNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLL 1681
Query: 200 QSKADEANRTLNDLDAAKKKLS---IENSDLLRQLEEAE-SQVSQLSKIKVSLT---TQL 358
Q++ +E + + ++K IE S+ ++ L S ++Q K+ L+ T++
Sbjct: 1682 QAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEV 1741
Query: 359 EDTK---RLADEEARERAT---LLGKFRNLEHDLDNIREQVEEEAEGKA-DLQRQLSKAN 517
E+ R A+E+A++ T ++ + E D E++++ E DLQ +L +A
Sbjct: 1742 EEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAE 1801
Query: 518 AEAQLWRSKYESEGVARSEELE---EAKRKLQAR----LAEAEETIESLNQKVVALEKTK 676
A K + AR ELE EA++K A + ++E I+ L + K
Sbjct: 1802 QIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNL 1861
Query: 677 QRLATEVEDLQLEV 718
RL V+ LQL+V
Sbjct: 1862 LRLQDLVDKLQLKV 1875
Score = 47.6 bits (108), Expect = 5e-05
Identities = 51/234 (21%), Positives = 103/234 (44%), Gaps = 8/234 (3%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD 214
E L+ L K + + + E++DL L EK+ KQL+ + E+QS +
Sbjct: 1490 ESLEHLETFKRENKNLQ----EEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALE 1545
Query: 215 EANRTLNDLDAAKKKLSIE----NSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLAD 382
EA +L + + +E +++ R+L E + ++ Q + + + L+ + D
Sbjct: 1546 EAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTS---LD 1602
Query: 383 EEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGV 562
E R R L + +E DL+ + Q+ A+ Q+Q+ + + + + + + V
Sbjct: 1603 AETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLD-DAV 1661
Query: 563 ARSEELEE----AKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQL 712
+++L+E +R+ AE EE + Q + + +Q L E +QL
Sbjct: 1662 RANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQL 1715
Score = 43.2 bits (97), Expect = 0.001
Identities = 49/202 (24%), Positives = 88/202 (43%), Gaps = 13/202 (6%)
Frame = +2
Query: 143 EKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQ 322
E A+ ++ +L+ L + +++ E + L K L ++ L +AE + Q
Sbjct: 848 EMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQ 907
Query: 323 LSKIKVSLTTQ-------LEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEG 481
L K K+ L + LED E A L K R LE + ++ ++
Sbjct: 908 LIKNKIQLEAKVKEMNERLED-------EEEMNAELTAKKRKLEDECSELKRDID----- 955
Query: 482 KADLQRQLSKANAEAQLWRSKYE--SEGVARSEE----LEEAKRKLQARLAEAEETIESL 643
DL+ L+K E +K + +E +A +E L + K+ LQ +A + +++
Sbjct: 956 --DLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAE 1013
Query: 644 NQKVVALEKTKQRLATEVEDLQ 709
KV L K K +L +V+DL+
Sbjct: 1014 EDKVNTLTKAKVKLEQQVDDLE 1035
Score = 30.7 bits (66), Expect = 6.2
Identities = 23/86 (26%), Positives = 45/86 (52%), Gaps = 3/86 (3%)
Frame = +2
Query: 455 EQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQAR---LAEAE 625
E+ +E A K + R L +A +++ R + E + V+ +E + + ++QA LA+AE
Sbjct: 844 EREKEMASMKEEFTR-LKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAE 902
Query: 626 ETIESLNQKVVALEKTKQRLATEVED 703
E + L + + LE + + +ED
Sbjct: 903 ERCDQLIKNKIQLEAKVKEMNERLED 928
>BC112173-1|AAI12174.1| 1935|Homo sapiens myosin, heavy chain 7,
cardiac muscle, beta protein.
Length = 1935
Score = 233 bits (571), Expect = 4e-61
Identities = 110/235 (46%), Positives = 167/235 (71%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
V+++GEQ+D L ++K K EK ++++ E++D+ + ++ + KA EK+ + L+ Q+NE
Sbjct: 1200 VAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEH 1259
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
+SKA+E R++NDL + + KL EN +L RQL+E E+ +SQL++ K++ T QLED KR
Sbjct: 1260 RSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQL 1319
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEG 559
+EE + + L ++ HD D +REQ EEE E KA+LQR LSKAN+E WR+KYE++
Sbjct: 1320 EEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDA 1379
Query: 560 VARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
+ R+EELEEAK+KL RL EAEE +E++N K +LEKTK RL E+EDL ++V+R
Sbjct: 1380 IQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVER 1434
Score = 73.7 bits (173), Expect = 7e-13
Identities = 51/237 (21%), Positives = 109/237 (45%), Gaps = 1/237 (0%)
Frame = +2
Query: 14 RFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLN 193
R V + LD + + +A + + + ++N++ L H + A +K VK LQ L
Sbjct: 1592 RVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLK 1651
Query: 194 EVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKR 373
+ Q + D+A R +DL + N+ L +LEE + V Q + + +L +T
Sbjct: 1652 DTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSE 1711
Query: 374 LADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYES 553
+ +L+ + + ++ DL ++ +VEE + + + + KA +A + + +
Sbjct: 1712 RVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKK 1771
Query: 554 EGVARSEELEEAKRKLQARLAEAEETIESLNQ-KVVALEKTKQRLATEVEDLQLEVD 721
E S LE K+ ++ + + + ++ Q + +K Q+L V +L+ E++
Sbjct: 1772 E-QDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELE 1827
Score = 70.1 bits (164), Expect = 8e-12
Identities = 59/235 (25%), Positives = 109/235 (46%), Gaps = 1/235 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+ D+ + D++N L K + + +V+DL L+ + E+ ++L+ L
Sbjct: 1007 LDDLQAEEDKVNTLT----KAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLT 1062
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
Q + LD KK E + L ++E+ ++ SQL K L ++E+ +
Sbjct: 1063 QESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEEL 1122
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKAN-AEAQLWRSKYESE 556
+ E RA + +L +L+ I E++EE A G +Q +++K AE Q R E E
Sbjct: 1123 EAERTARAKVEKLRSDLSRELEEISERLEE-AGGATSVQIEMNKKREAEFQKMRRDLE-E 1180
Query: 557 GVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
+ E A RK A +++ L +++ L++ KQ+L E + +LE+D
Sbjct: 1181 ATLQHEATAAALRKKHA------DSVAELGEQIDNLQRVKQKLEKEKSEFKLELD 1229
Score = 64.9 bits (151), Expect = 3e-10
Identities = 50/231 (21%), Positives = 103/231 (44%), Gaps = 1/231 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+ D+ QL++ K K + + LR + + KA ++++ + ++ +
Sbjct: 1312 LEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQW 1371
Query: 200 QSKAD-EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRL 376
++K + +A + +L+ AKKKL+ + +E ++ S L K K L ++ED
Sbjct: 1372 RTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVD 1431
Query: 377 ADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESE 556
+ A L K RN + L +++ EE Q++ + E ++ YE E
Sbjct: 1432 VERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYE-E 1490
Query: 557 GVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQ 709
+ E + + LQ +++ E + S + + LEK +++L E +LQ
Sbjct: 1491 SLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQ 1541
Score = 59.7 bits (138), Expect = 1e-08
Identities = 46/235 (19%), Positives = 110/235 (46%), Gaps = 1/235 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+SD+ EQL K + EK R Q +E +L++ L+ +E + + Q + N++
Sbjct: 1509 ISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQI 1568
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQV-SQLSKIKVSLTTQLEDTKRL 376
+++ + ++ K+ + D L+ +AE++ ++ ++K + L + +
Sbjct: 1569 KAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQ 1628
Query: 377 ADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESE 556
R A + ++L+ L + + Q+++ DL+ ++ L +++ E E
Sbjct: 1629 LSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELE-E 1687
Query: 557 GVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
A E+ E +++ + L E E ++ L+ + +L K+++ ++ LQ EV+
Sbjct: 1688 LRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVE 1742
Score = 56.8 bits (131), Expect = 8e-08
Identities = 49/225 (21%), Positives = 100/225 (44%), Gaps = 6/225 (2%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+ ++ E+L+ +AK EK R+ E+ ++ L+ + Q ++ K+ + + ++
Sbjct: 1115 IEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKM 1174
Query: 200 QSKADEANRTLNDLDAAKKKLSIEN-SDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRL 376
+ +EA AA +K ++ ++L Q++ + +L K K +L+D
Sbjct: 1175 RRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSN 1234
Query: 377 ADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAE-AQLWRSKYES 553
++ + +A L R LE ++ R + EE DL Q +K E +L R E
Sbjct: 1235 MEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEK 1294
Query: 554 EGVARSEELEEAK----RKLQARLAEAEETIESLNQKVVALEKTK 676
E A +L K ++L+ + EE +++ N AL+ +
Sbjct: 1295 E--ALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSAR 1337
Score = 54.8 bits (126), Expect = 3e-07
Identities = 39/228 (17%), Positives = 98/228 (42%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
V D+ L+Q K++ E+ + + ++ + + L N+K ++ +K+ +LN +
Sbjct: 1031 VDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNAL 1090
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
++ ++ + L K+L +L +LE + +++ K++ L+ +LE+
Sbjct: 1091 NARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERL 1150
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEG 559
+E + + + E + +R +EE L K +A++ +
Sbjct: 1151 EEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNL 1210
Query: 560 VARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVED 703
++LE+ K + + L + +E + + LEK + L ++ +
Sbjct: 1211 QRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNE 1258
Score = 53.2 bits (122), Expect = 1e-06
Identities = 48/217 (22%), Positives = 90/217 (41%), Gaps = 1/217 (0%)
Frame = +2
Query: 74 EKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAK 253
E+ + + V+ L+ LD + + ++ K+++ LNE++ + ANR +
Sbjct: 1584 EQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQV 1643
Query: 254 KKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNL- 430
K L D QL++A L K +++ + + + EE R + R L
Sbjct: 1644 KSLQSLLKDTQIQLDDAVRANDDL-KENIAIVERRNNLLQAELEELRAVVEQTERSRKLA 1702
Query: 431 EHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQAR 610
E +L E+V+ L Q K +A+ +++ E E V EE +K
Sbjct: 1703 EQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVE-EAVQECRNAEEKAKKAITD 1761
Query: 611 LAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
A E ++ LE+ K+ + ++DLQ +D
Sbjct: 1762 AAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLD 1798
Score = 50.8 bits (116), Expect = 5e-06
Identities = 47/215 (21%), Positives = 104/215 (48%), Gaps = 8/215 (3%)
Frame = +2
Query: 101 EVNDLRAGLDHLSNEKAAQ-EKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENS 277
E N ++A ++ EK + E+ + ++ +Q+ D R+ N+ KKK+ + +
Sbjct: 1564 EFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLN 1623
Query: 278 DLLRQLEEAESQVSQLSKIKVSLTTQLEDTK-RL-----ADEEARERATLLGKFRN-LEH 436
++ QL A ++ K SL + L+DT+ +L A+++ +E ++ + N L+
Sbjct: 1624 EMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQA 1683
Query: 437 DLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLA 616
+L+ +R VE+ + +++L + + QL S+ S + + ++++ +LQ +
Sbjct: 1684 ELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSL-INQKKKMDADLSQLQTEVE 1742
Query: 617 EAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
EA + + +K +K A E+L+ E D
Sbjct: 1743 EAVQECRNAEEKA---KKAITDAAMMAEELKKEQD 1774
Score = 50.0 bits (114), Expect = 9e-06
Identities = 39/169 (23%), Positives = 80/169 (47%), Gaps = 2/169 (1%)
Frame = +2
Query: 29 MGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSN-EKAAQEKIVKQLQHQLNEVQS 205
M E+L + A E+ + + DL+ LD +K +++L+ ++ E+++
Sbjct: 1765 MAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEN 1824
Query: 206 KADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADE 385
+ + + + +K +L Q EE + +L + L +++ KR A+E
Sbjct: 1825 ELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEE 1884
Query: 386 EARERATLLGKFRNLEHDLDNIREQVEEEAEGKADL-QRQLSKANAEAQ 529
+ T L KFR ++H+LD EAE +AD+ + Q++K A+++
Sbjct: 1885 AEEQANTNLSKFRKVQHELD--------EAEERADIAESQVNKLRAKSR 1925
Score = 48.0 bits (109), Expect = 4e-05
Identities = 61/254 (24%), Positives = 117/254 (46%), Gaps = 21/254 (8%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+++M QL N++ A+A+K S + D + LD ++ + ++ + N +
Sbjct: 1622 LNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLL 1681
Query: 200 QSKADEANRTLNDLDAAKKKLS---IENSDLLRQLEEAE-SQVSQLSKIKVSLT---TQL 358
Q++ +E + + ++K IE S+ ++ L S ++Q K+ L+ T++
Sbjct: 1682 QAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEV 1741
Query: 359 EDTK---RLADEEARERAT---LLGKFRNLEHDLDNIREQVEEEAEGKA-DLQRQLSKAN 517
E+ R A+E+A++ T ++ + E D E++++ E DLQ +L +A
Sbjct: 1742 EEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAE 1801
Query: 518 AEAQLWRSKYESEGVARSEELE---EAKRKLQAR----LAEAEETIESLNQKVVALEKTK 676
A K + AR ELE EA++K A + ++E I+ L + K
Sbjct: 1802 QIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNL 1861
Query: 677 QRLATEVEDLQLEV 718
RL V+ LQL+V
Sbjct: 1862 LRLQDLVDKLQLKV 1875
Score = 47.6 bits (108), Expect = 5e-05
Identities = 51/234 (21%), Positives = 103/234 (44%), Gaps = 8/234 (3%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD 214
E L+ L K + + + E++DL L EK+ KQL+ + E+QS +
Sbjct: 1490 ESLEHLETFKRENKNLQ----EEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALE 1545
Query: 215 EANRTLNDLDAAKKKLSIE----NSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLAD 382
EA +L + + +E +++ R+L E + ++ Q + + + L+ + D
Sbjct: 1546 EAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTS---LD 1602
Query: 383 EEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGV 562
E R R L + +E DL+ + Q+ A+ Q+Q+ + + + + + + V
Sbjct: 1603 AETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLD-DAV 1661
Query: 563 ARSEELEE----AKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQL 712
+++L+E +R+ AE EE + Q + + +Q L E +QL
Sbjct: 1662 RANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQL 1715
Score = 43.2 bits (97), Expect = 0.001
Identities = 49/202 (24%), Positives = 88/202 (43%), Gaps = 13/202 (6%)
Frame = +2
Query: 143 EKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQ 322
E A+ ++ +L+ L + +++ E + L K L ++ L +AE + Q
Sbjct: 848 EMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQ 907
Query: 323 LSKIKVSLTTQ-------LEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEG 481
L K K+ L + LED E A L K R LE + ++ ++
Sbjct: 908 LIKNKIQLEAKVKEMNERLED-------EEEMNAELTAKKRKLEDECSELKRDID----- 955
Query: 482 KADLQRQLSKANAEAQLWRSKYE--SEGVARSEE----LEEAKRKLQARLAEAEETIESL 643
DL+ L+K E +K + +E +A +E L + K+ LQ +A + +++
Sbjct: 956 --DLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAE 1013
Query: 644 NQKVVALEKTKQRLATEVEDLQ 709
KV L K K +L +V+DL+
Sbjct: 1014 EDKVNTLTKAKVKLEQQVDDLE 1035
Score = 30.7 bits (66), Expect = 6.2
Identities = 23/86 (26%), Positives = 45/86 (52%), Gaps = 3/86 (3%)
Frame = +2
Query: 455 EQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQAR---LAEAE 625
E+ +E A K + R L +A +++ R + E + V+ +E + + ++QA LA+AE
Sbjct: 844 EREKEMASMKEEFTR-LKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAE 902
Query: 626 ETIESLNQKVVALEKTKQRLATEVED 703
E + L + + LE + + +ED
Sbjct: 903 ERCDQLIKNKIQLEAKVKEMNERLED 928
>BC112171-1|AAI12172.1| 1935|Homo sapiens myosin, heavy chain 7,
cardiac muscle, beta protein.
Length = 1935
Score = 233 bits (571), Expect = 4e-61
Identities = 110/235 (46%), Positives = 167/235 (71%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
V+++GEQ+D L ++K K EK ++++ E++D+ + ++ + KA EK+ + L+ Q+NE
Sbjct: 1200 VAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEH 1259
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
+SKA+E R++NDL + + KL EN +L RQL+E E+ +SQL++ K++ T QLED KR
Sbjct: 1260 RSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQL 1319
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEG 559
+EE + + L ++ HD D +REQ EEE E KA+LQR LSKAN+E WR+KYE++
Sbjct: 1320 EEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDA 1379
Query: 560 VARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
+ R+EELEEAK+KL RL EAEE +E++N K +LEKTK RL E+EDL ++V+R
Sbjct: 1380 IQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVER 1434
Score = 73.7 bits (173), Expect = 7e-13
Identities = 51/237 (21%), Positives = 109/237 (45%), Gaps = 1/237 (0%)
Frame = +2
Query: 14 RFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLN 193
R V + LD + + +A + + + ++N++ L H + A +K VK LQ L
Sbjct: 1592 RVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLK 1651
Query: 194 EVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKR 373
+ Q + D+A R +DL + N+ L +LEE + V Q + + +L +T
Sbjct: 1652 DTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSE 1711
Query: 374 LADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYES 553
+ +L+ + + ++ DL ++ +VEE + + + + KA +A + + +
Sbjct: 1712 RVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKK 1771
Query: 554 EGVARSEELEEAKRKLQARLAEAEETIESLNQ-KVVALEKTKQRLATEVEDLQLEVD 721
E S LE K+ ++ + + + ++ Q + +K Q+L V +L+ E++
Sbjct: 1772 E-QDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELE 1827
Score = 70.1 bits (164), Expect = 8e-12
Identities = 59/235 (25%), Positives = 109/235 (46%), Gaps = 1/235 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+ D+ + D++N L K + + +V+DL L+ + E+ ++L+ L
Sbjct: 1007 LDDLQAEEDKVNTLT----KAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLT 1062
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
Q + LD KK E + L ++E+ ++ SQL K L ++E+ +
Sbjct: 1063 QESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEEL 1122
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKAN-AEAQLWRSKYESE 556
+ E RA + +L +L+ I E++EE A G +Q +++K AE Q R E E
Sbjct: 1123 EAERTARAKVEKLRSDLSRELEEISERLEE-AGGATSVQIEMNKKREAEFQKMRRDLE-E 1180
Query: 557 GVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
+ E A RK A +++ L +++ L++ KQ+L E + +LE+D
Sbjct: 1181 ATLQHEATAAALRKKHA------DSVAELGEQIDNLQRVKQKLEKEKSEFKLELD 1229
Score = 64.9 bits (151), Expect = 3e-10
Identities = 50/231 (21%), Positives = 103/231 (44%), Gaps = 1/231 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+ D+ QL++ K K + + LR + + KA ++++ + ++ +
Sbjct: 1312 LEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQW 1371
Query: 200 QSKAD-EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRL 376
++K + +A + +L+ AKKKL+ + +E ++ S L K K L ++ED
Sbjct: 1372 RTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVD 1431
Query: 377 ADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESE 556
+ A L K RN + L +++ EE Q++ + E ++ YE E
Sbjct: 1432 VERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYE-E 1490
Query: 557 GVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQ 709
+ E + + LQ +++ E + S + + LEK +++L E +LQ
Sbjct: 1491 SLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQ 1541
Score = 59.7 bits (138), Expect = 1e-08
Identities = 46/235 (19%), Positives = 110/235 (46%), Gaps = 1/235 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+SD+ EQL K + EK R Q +E +L++ L+ +E + + Q + N++
Sbjct: 1509 ISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQI 1568
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQV-SQLSKIKVSLTTQLEDTKRL 376
+++ + ++ K+ + D L+ +AE++ ++ ++K + L + +
Sbjct: 1569 KAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQ 1628
Query: 377 ADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESE 556
R A + ++L+ L + + Q+++ DL+ ++ L +++ E E
Sbjct: 1629 LSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELE-E 1687
Query: 557 GVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
A E+ E +++ + L E E ++ L+ + +L K+++ ++ LQ EV+
Sbjct: 1688 LRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVE 1742
Score = 56.8 bits (131), Expect = 8e-08
Identities = 49/225 (21%), Positives = 100/225 (44%), Gaps = 6/225 (2%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+ ++ E+L+ +AK EK R+ E+ ++ L+ + Q ++ K+ + + ++
Sbjct: 1115 IEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKM 1174
Query: 200 QSKADEANRTLNDLDAAKKKLSIEN-SDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRL 376
+ +EA AA +K ++ ++L Q++ + +L K K +L+D
Sbjct: 1175 RRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSN 1234
Query: 377 ADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAE-AQLWRSKYES 553
++ + +A L R LE ++ R + EE DL Q +K E +L R E
Sbjct: 1235 MEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEK 1294
Query: 554 EGVARSEELEEAK----RKLQARLAEAEETIESLNQKVVALEKTK 676
E A +L K ++L+ + EE +++ N AL+ +
Sbjct: 1295 E--ALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSAR 1337
Score = 54.8 bits (126), Expect = 3e-07
Identities = 39/228 (17%), Positives = 98/228 (42%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
V D+ L+Q K++ E+ + + ++ + + L N+K ++ +K+ +LN +
Sbjct: 1031 VDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNAL 1090
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
++ ++ + L K+L +L +LE + +++ K++ L+ +LE+
Sbjct: 1091 NARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERL 1150
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEG 559
+E + + + E + +R +EE L K +A++ +
Sbjct: 1151 EEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNL 1210
Query: 560 VARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVED 703
++LE+ K + + L + +E + + LEK + L ++ +
Sbjct: 1211 QRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNE 1258
Score = 53.2 bits (122), Expect = 1e-06
Identities = 48/217 (22%), Positives = 90/217 (41%), Gaps = 1/217 (0%)
Frame = +2
Query: 74 EKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAK 253
E+ + + V+ L+ LD + + ++ K+++ LNE++ + ANR +
Sbjct: 1584 EQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQV 1643
Query: 254 KKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNL- 430
K L D QL++A L K +++ + + + EE R + R L
Sbjct: 1644 KSLQSLLKDTQIQLDDAVRANDDL-KENIAIVERRNNLLQAELEELRAVVEQTERSRKLA 1702
Query: 431 EHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQAR 610
E +L E+V+ L Q K +A+ +++ E E V EE +K
Sbjct: 1703 EQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVE-EAVQECRNAEEKAKKAITD 1761
Query: 611 LAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
A E ++ LE+ K+ + ++DLQ +D
Sbjct: 1762 AAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLD 1798
Score = 50.8 bits (116), Expect = 5e-06
Identities = 47/215 (21%), Positives = 104/215 (48%), Gaps = 8/215 (3%)
Frame = +2
Query: 101 EVNDLRAGLDHLSNEKAAQ-EKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENS 277
E N ++A ++ EK + E+ + ++ +Q+ D R+ N+ KKK+ + +
Sbjct: 1564 EFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLN 1623
Query: 278 DLLRQLEEAESQVSQLSKIKVSLTTQLEDTK-RL-----ADEEARERATLLGKFRN-LEH 436
++ QL A ++ K SL + L+DT+ +L A+++ +E ++ + N L+
Sbjct: 1624 EMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQA 1683
Query: 437 DLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLA 616
+L+ +R VE+ + +++L + + QL S+ S + + ++++ +LQ +
Sbjct: 1684 ELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSL-INQKKKMDADLSQLQTEVE 1742
Query: 617 EAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
EA + + +K +K A E+L+ E D
Sbjct: 1743 EAVQECRNAEEKA---KKAITDAAMMAEELKKEQD 1774
Score = 50.0 bits (114), Expect = 9e-06
Identities = 39/169 (23%), Positives = 80/169 (47%), Gaps = 2/169 (1%)
Frame = +2
Query: 29 MGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSN-EKAAQEKIVKQLQHQLNEVQS 205
M E+L + A E+ + + DL+ LD +K +++L+ ++ E+++
Sbjct: 1765 MAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEN 1824
Query: 206 KADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADE 385
+ + + + +K +L Q EE + +L + L +++ KR A+E
Sbjct: 1825 ELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEE 1884
Query: 386 EARERATLLGKFRNLEHDLDNIREQVEEEAEGKADL-QRQLSKANAEAQ 529
+ T L KFR ++H+LD EAE +AD+ + Q++K A+++
Sbjct: 1885 AEEQANTNLSKFRKVQHELD--------EAEERADIAESQVNKLRAKSR 1925
Score = 48.0 bits (109), Expect = 4e-05
Identities = 61/254 (24%), Positives = 117/254 (46%), Gaps = 21/254 (8%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+++M QL N++ A+A+K S + D + LD ++ + ++ + N +
Sbjct: 1622 LNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLL 1681
Query: 200 QSKADEANRTLNDLDAAKKKLS---IENSDLLRQLEEAE-SQVSQLSKIKVSLT---TQL 358
Q++ +E + + ++K IE S+ ++ L S ++Q K+ L+ T++
Sbjct: 1682 QAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEV 1741
Query: 359 EDTK---RLADEEARERAT---LLGKFRNLEHDLDNIREQVEEEAEGKA-DLQRQLSKAN 517
E+ R A+E+A++ T ++ + E D E++++ E DLQ +L +A
Sbjct: 1742 EEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAE 1801
Query: 518 AEAQLWRSKYESEGVARSEELE---EAKRKLQAR----LAEAEETIESLNQKVVALEKTK 676
A K + AR ELE EA++K A + ++E I+ L + K
Sbjct: 1802 QIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNL 1861
Query: 677 QRLATEVEDLQLEV 718
RL V+ LQL+V
Sbjct: 1862 LRLQDLVDKLQLKV 1875
Score = 47.6 bits (108), Expect = 5e-05
Identities = 51/234 (21%), Positives = 103/234 (44%), Gaps = 8/234 (3%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD 214
E L+ L K + + + E++DL L EK+ KQL+ + E+QS +
Sbjct: 1490 ESLEHLETFKRENKNLQ----EEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALE 1545
Query: 215 EANRTLNDLDAAKKKLSIE----NSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLAD 382
EA +L + + +E +++ R+L E + ++ Q + + + L+ + D
Sbjct: 1546 EAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTS---LD 1602
Query: 383 EEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGV 562
E R R L + +E DL+ + Q+ A+ Q+Q+ + + + + + + V
Sbjct: 1603 AETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLD-DAV 1661
Query: 563 ARSEELEE----AKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQL 712
+++L+E +R+ AE EE + Q + + +Q L E +QL
Sbjct: 1662 RANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQL 1715
Score = 43.2 bits (97), Expect = 0.001
Identities = 49/202 (24%), Positives = 88/202 (43%), Gaps = 13/202 (6%)
Frame = +2
Query: 143 EKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQ 322
E A+ ++ +L+ L + +++ E + L K L ++ L +AE + Q
Sbjct: 848 EMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQ 907
Query: 323 LSKIKVSLTTQ-------LEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEG 481
L K K+ L + LED E A L K R LE + ++ ++
Sbjct: 908 LIKNKIQLEAKVKEMNERLED-------EEEMNAELTAKKRKLEDECSELKRDID----- 955
Query: 482 KADLQRQLSKANAEAQLWRSKYE--SEGVARSEE----LEEAKRKLQARLAEAEETIESL 643
DL+ L+K E +K + +E +A +E L + K+ LQ +A + +++
Sbjct: 956 --DLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAE 1013
Query: 644 NQKVVALEKTKQRLATEVEDLQ 709
KV L K K +L +V+DL+
Sbjct: 1014 EDKVNTLTKAKVKLEQQVDDLE 1035
Score = 30.7 bits (66), Expect = 6.2
Identities = 23/86 (26%), Positives = 45/86 (52%), Gaps = 3/86 (3%)
Frame = +2
Query: 455 EQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQAR---LAEAE 625
E+ +E A K + R L +A +++ R + E + V+ +E + + ++QA LA+AE
Sbjct: 844 EREKEMASMKEEFTR-LKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAE 902
Query: 626 ETIESLNQKVVALEKTKQRLATEVED 703
E + L + + LE + + +ED
Sbjct: 903 ERCDQLIKNKIQLEAKVKEMNERLED 928
>AJ238393-1|CAC20413.1| 1935|Homo sapiens beta-myosin heavy chain
protein.
Length = 1935
Score = 233 bits (571), Expect = 4e-61
Identities = 110/235 (46%), Positives = 167/235 (71%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
V+++GEQ+D L ++K K EK ++++ E++D+ + ++ + KA EK+ + L+ Q+NE
Sbjct: 1200 VAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEH 1259
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
+SKA+E R++NDL + + KL EN +L RQL+E E+ +SQL++ K++ T QLED KR
Sbjct: 1260 RSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQL 1319
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEG 559
+EE + + L ++ HD D +REQ EEE E KA+LQR LSKAN+E WR+KYE++
Sbjct: 1320 EEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDA 1379
Query: 560 VARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
+ R+EELEEAK+KL RL EAEE +E++N K +LEKTK RL E+EDL ++V+R
Sbjct: 1380 IQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVER 1434
Score = 73.7 bits (173), Expect = 7e-13
Identities = 51/237 (21%), Positives = 109/237 (45%), Gaps = 1/237 (0%)
Frame = +2
Query: 14 RFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLN 193
R V + LD + + +A + + + ++N++ L H + A +K VK LQ L
Sbjct: 1592 RVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLK 1651
Query: 194 EVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKR 373
+ Q + D+A R +DL + N+ L +LEE + V Q + + +L +T
Sbjct: 1652 DTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSE 1711
Query: 374 LADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYES 553
+ +L+ + + ++ DL ++ +VEE + + + + KA +A + + +
Sbjct: 1712 RVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKK 1771
Query: 554 EGVARSEELEEAKRKLQARLAEAEETIESLNQ-KVVALEKTKQRLATEVEDLQLEVD 721
E S LE K+ ++ + + + ++ Q + +K Q+L V +L+ E++
Sbjct: 1772 E-QDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELE 1827
Score = 69.3 bits (162), Expect = 1e-11
Identities = 59/235 (25%), Positives = 108/235 (45%), Gaps = 1/235 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+ D+ + D++N L K + + +V+DL L+ + E+ ++L+ L
Sbjct: 1007 LDDLQAEEDKVNTLT----KAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLT 1062
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
Q + LD KK E + L ++E+ ++ SQL K L ++E+ +
Sbjct: 1063 QESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEEL 1122
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKAN-AEAQLWRSKYESE 556
+ E RA + +L +L+ I E++EE A G Q +++K AE Q R E E
Sbjct: 1123 EAERTARAKVEKLRSDLSRELEEISERLEE-AGGATSCQIEMNKKREAEFQKMRRDLE-E 1180
Query: 557 GVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
+ E A RK A +++ L +++ L++ KQ+L E + +LE+D
Sbjct: 1181 ATLQHEATAAALRKKHA------DSVAELGEQIDNLQRVKQKLEKEKSEFKLELD 1229
Score = 64.9 bits (151), Expect = 3e-10
Identities = 50/231 (21%), Positives = 103/231 (44%), Gaps = 1/231 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+ D+ QL++ K K + + LR + + KA ++++ + ++ +
Sbjct: 1312 LEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQW 1371
Query: 200 QSKAD-EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRL 376
++K + +A + +L+ AKKKL+ + +E ++ S L K K L ++ED
Sbjct: 1372 RTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVD 1431
Query: 377 ADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESE 556
+ A L K RN + L +++ EE Q++ + E ++ YE E
Sbjct: 1432 VERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYE-E 1490
Query: 557 GVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQ 709
+ E + + LQ +++ E + S + + LEK +++L E +LQ
Sbjct: 1491 SLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQ 1541
Score = 59.7 bits (138), Expect = 1e-08
Identities = 46/235 (19%), Positives = 110/235 (46%), Gaps = 1/235 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+SD+ EQL K + EK R Q +E +L++ L+ +E + + Q + N++
Sbjct: 1509 ISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQI 1568
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQV-SQLSKIKVSLTTQLEDTKRL 376
+++ + ++ K+ + D L+ +AE++ ++ ++K + L + +
Sbjct: 1569 KAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQ 1628
Query: 377 ADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESE 556
R A + ++L+ L + + Q+++ DL+ ++ L +++ E E
Sbjct: 1629 LSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELE-E 1687
Query: 557 GVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
A E+ E +++ + L E E ++ L+ + +L K+++ ++ LQ EV+
Sbjct: 1688 LRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVE 1742
Score = 56.8 bits (131), Expect = 8e-08
Identities = 49/225 (21%), Positives = 100/225 (44%), Gaps = 6/225 (2%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+ ++ E+L+ +AK EK R+ E+ ++ L+ + Q ++ K+ + + ++
Sbjct: 1115 IEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSCQIEMNKKREAEFQKM 1174
Query: 200 QSKADEANRTLNDLDAAKKKLSIEN-SDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRL 376
+ +EA AA +K ++ ++L Q++ + +L K K +L+D
Sbjct: 1175 RRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSN 1234
Query: 377 ADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAE-AQLWRSKYES 553
++ + +A L R LE ++ R + EE DL Q +K E +L R E
Sbjct: 1235 MEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEK 1294
Query: 554 EGVARSEELEEAK----RKLQARLAEAEETIESLNQKVVALEKTK 676
E A +L K ++L+ + EE +++ N AL+ +
Sbjct: 1295 E--ALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSAR 1337
Score = 54.4 bits (125), Expect = 4e-07
Identities = 39/228 (17%), Positives = 98/228 (42%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
V D+ L+Q K++ E+ + + ++ + + L N+K ++ +K+ +LN +
Sbjct: 1031 VDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNAL 1090
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
++ ++ + L K+L +L +LE + +++ K++ L+ +LE+
Sbjct: 1091 NARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERL 1150
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEG 559
+E + + + E + +R +EE L K +A++ +
Sbjct: 1151 EEAGGATSCQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNL 1210
Query: 560 VARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVED 703
++LE+ K + + L + +E + + LEK + L ++ +
Sbjct: 1211 QRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNE 1258
Score = 53.2 bits (122), Expect = 1e-06
Identities = 48/217 (22%), Positives = 90/217 (41%), Gaps = 1/217 (0%)
Frame = +2
Query: 74 EKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAK 253
E+ + + V+ L+ LD + + ++ K+++ LNE++ + ANR +
Sbjct: 1584 EQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQV 1643
Query: 254 KKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNL- 430
K L D QL++A L K +++ + + + EE R + R L
Sbjct: 1644 KSLQSLLKDTQIQLDDAVRANDDL-KENIAIVERRNNLLQAELEELRAVVEQTERSRKLA 1702
Query: 431 EHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQAR 610
E +L E+V+ L Q K +A+ +++ E E V EE +K
Sbjct: 1703 EQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVE-EAVQECRNAEEKAKKAITD 1761
Query: 611 LAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
A E ++ LE+ K+ + ++DLQ +D
Sbjct: 1762 AAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLD 1798
Score = 50.8 bits (116), Expect = 5e-06
Identities = 47/215 (21%), Positives = 104/215 (48%), Gaps = 8/215 (3%)
Frame = +2
Query: 101 EVNDLRAGLDHLSNEKAAQ-EKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENS 277
E N ++A ++ EK + E+ + ++ +Q+ D R+ N+ KKK+ + +
Sbjct: 1564 EFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLN 1623
Query: 278 DLLRQLEEAESQVSQLSKIKVSLTTQLEDTK-RL-----ADEEARERATLLGKFRN-LEH 436
++ QL A ++ K SL + L+DT+ +L A+++ +E ++ + N L+
Sbjct: 1624 EMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQA 1683
Query: 437 DLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLA 616
+L+ +R VE+ + +++L + + QL S+ S + + ++++ +LQ +
Sbjct: 1684 ELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSL-INQKKKMDADLSQLQTEVE 1742
Query: 617 EAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
EA + + +K +K A E+L+ E D
Sbjct: 1743 EAVQECRNAEEKA---KKAITDAAMMAEELKKEQD 1774
Score = 50.0 bits (114), Expect = 9e-06
Identities = 39/169 (23%), Positives = 80/169 (47%), Gaps = 2/169 (1%)
Frame = +2
Query: 29 MGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSN-EKAAQEKIVKQLQHQLNEVQS 205
M E+L + A E+ + + DL+ LD +K +++L+ ++ E+++
Sbjct: 1765 MAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEN 1824
Query: 206 KADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADE 385
+ + + + +K +L Q EE + +L + L +++ KR A+E
Sbjct: 1825 ELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEE 1884
Query: 386 EARERATLLGKFRNLEHDLDNIREQVEEEAEGKADL-QRQLSKANAEAQ 529
+ T L KFR ++H+LD EAE +AD+ + Q++K A+++
Sbjct: 1885 AEEQANTNLSKFRKVQHELD--------EAEERADIAESQVNKLRAKSR 1925
Score = 48.0 bits (109), Expect = 4e-05
Identities = 61/254 (24%), Positives = 117/254 (46%), Gaps = 21/254 (8%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+++M QL N++ A+A+K S + D + LD ++ + ++ + N +
Sbjct: 1622 LNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLL 1681
Query: 200 QSKADEANRTLNDLDAAKKKLS---IENSDLLRQLEEAE-SQVSQLSKIKVSLT---TQL 358
Q++ +E + + ++K IE S+ ++ L S ++Q K+ L+ T++
Sbjct: 1682 QAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEV 1741
Query: 359 EDTK---RLADEEARERAT---LLGKFRNLEHDLDNIREQVEEEAEGKA-DLQRQLSKAN 517
E+ R A+E+A++ T ++ + E D E++++ E DLQ +L +A
Sbjct: 1742 EEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAE 1801
Query: 518 AEAQLWRSKYESEGVARSEELE---EAKRKLQAR----LAEAEETIESLNQKVVALEKTK 676
A K + AR ELE EA++K A + ++E I+ L + K
Sbjct: 1802 QIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNL 1861
Query: 677 QRLATEVEDLQLEV 718
RL V+ LQL+V
Sbjct: 1862 LRLQDLVDKLQLKV 1875
Score = 47.6 bits (108), Expect = 5e-05
Identities = 51/234 (21%), Positives = 103/234 (44%), Gaps = 8/234 (3%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD 214
E L+ L K + + + E++DL L EK+ KQL+ + E+QS +
Sbjct: 1490 ESLEHLETFKRENKNLQ----EEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALE 1545
Query: 215 EANRTLNDLDAAKKKLSIE----NSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLAD 382
EA +L + + +E +++ R+L E + ++ Q + + + L+ + D
Sbjct: 1546 EAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTS---LD 1602
Query: 383 EEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGV 562
E R R L + +E DL+ + Q+ A+ Q+Q+ + + + + + + V
Sbjct: 1603 AETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLD-DAV 1661
Query: 563 ARSEELEE----AKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQL 712
+++L+E +R+ AE EE + Q + + +Q L E +QL
Sbjct: 1662 RANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQL 1715
Score = 43.2 bits (97), Expect = 0.001
Identities = 49/202 (24%), Positives = 88/202 (43%), Gaps = 13/202 (6%)
Frame = +2
Query: 143 EKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQ 322
E A+ ++ +L+ L + +++ E + L K L ++ L +AE + Q
Sbjct: 848 EMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQ 907
Query: 323 LSKIKVSLTTQ-------LEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEG 481
L K K+ L + LED E A L K R LE + ++ ++
Sbjct: 908 LIKNKIQLEAKVKEMNERLED-------EEEMNAELTAKKRKLEDECSELKRDID----- 955
Query: 482 KADLQRQLSKANAEAQLWRSKYE--SEGVARSEE----LEEAKRKLQARLAEAEETIESL 643
DL+ L+K E +K + +E +A +E L + K+ LQ +A + +++
Sbjct: 956 --DLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAE 1013
Query: 644 NQKVVALEKTKQRLATEVEDLQ 709
KV L K K +L +V+DL+
Sbjct: 1014 EDKVNTLTKAKVKLEQQVDDLE 1035
Score = 30.7 bits (66), Expect = 6.2
Identities = 23/86 (26%), Positives = 45/86 (52%), Gaps = 3/86 (3%)
Frame = +2
Query: 455 EQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQAR---LAEAE 625
E+ +E A K + R L +A +++ R + E + V+ +E + + ++QA LA+AE
Sbjct: 844 EREKEMASMKEEFTR-LKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAE 902
Query: 626 ETIESLNQKVVALEKTKQRLATEVED 703
E + L + + LE + + +ED
Sbjct: 903 ERCDQLIKNKIQLEAKVKEMNERLED 928
>AB209708-1|BAD92945.1| 1574|Homo sapiens myosin, heavy polypeptide 7,
cardiac muscle, beta variant protein.
Length = 1574
Score = 233 bits (571), Expect = 4e-61
Identities = 110/235 (46%), Positives = 167/235 (71%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
V+++GEQ+D L ++K K EK ++++ E++D+ + ++ + KA EK+ + L+ Q+NE
Sbjct: 839 VAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEH 898
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
+SKA+E R++NDL + + KL EN +L RQL+E E+ +SQL++ K++ T QLED KR
Sbjct: 899 RSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQL 958
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEG 559
+EE + + L ++ HD D +REQ EEE E KA+LQR LSKAN+E WR+KYE++
Sbjct: 959 EEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDA 1018
Query: 560 VARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
+ R+EELEEAK+KL RL EAEE +E++N K +LEKTK RL E+EDL ++V+R
Sbjct: 1019 IQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVER 1073
Score = 73.7 bits (173), Expect = 7e-13
Identities = 51/237 (21%), Positives = 109/237 (45%), Gaps = 1/237 (0%)
Frame = +2
Query: 14 RFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLN 193
R V + LD + + +A + + + ++N++ L H + A +K VK LQ L
Sbjct: 1231 RVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLK 1290
Query: 194 EVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKR 373
+ Q + D+A R +DL + N+ L +LEE + V Q + + +L +T
Sbjct: 1291 DTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSE 1350
Query: 374 LADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYES 553
+ +L+ + + ++ DL ++ +VEE + + + + KA +A + + +
Sbjct: 1351 RVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKK 1410
Query: 554 EGVARSEELEEAKRKLQARLAEAEETIESLNQ-KVVALEKTKQRLATEVEDLQLEVD 721
E S LE K+ ++ + + + ++ Q + +K Q+L V +L+ E++
Sbjct: 1411 E-QDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELE 1466
Score = 70.1 bits (164), Expect = 8e-12
Identities = 59/235 (25%), Positives = 109/235 (46%), Gaps = 1/235 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+ D+ + D++N L K + + +V+DL L+ + E+ ++L+ L
Sbjct: 646 LDDLQAEEDKVNTLT----KAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLT 701
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
Q + LD KK E + L ++E+ ++ SQL K L ++E+ +
Sbjct: 702 QESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEEL 761
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKAN-AEAQLWRSKYESE 556
+ E RA + +L +L+ I E++EE A G +Q +++K AE Q R E E
Sbjct: 762 EAERTARAKVEKLRSDLSRELEEISERLEE-AGGATSVQIEMNKKREAEFQKMRRDLE-E 819
Query: 557 GVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
+ E A RK A +++ L +++ L++ KQ+L E + +LE+D
Sbjct: 820 ATLQHEATAAALRKKHA------DSVAELGEQIDNLQRVKQKLEKEKSEFKLELD 868
Score = 64.9 bits (151), Expect = 3e-10
Identities = 50/231 (21%), Positives = 103/231 (44%), Gaps = 1/231 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+ D+ QL++ K K + + LR + + KA ++++ + ++ +
Sbjct: 951 LEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQW 1010
Query: 200 QSKAD-EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRL 376
++K + +A + +L+ AKKKL+ + +E ++ S L K K L ++ED
Sbjct: 1011 RTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVD 1070
Query: 377 ADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESE 556
+ A L K RN + L +++ EE Q++ + E ++ YE E
Sbjct: 1071 VERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYE-E 1129
Query: 557 GVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQ 709
+ E + + LQ +++ E + S + + LEK +++L E +LQ
Sbjct: 1130 SLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQ 1180
Score = 59.7 bits (138), Expect = 1e-08
Identities = 46/235 (19%), Positives = 110/235 (46%), Gaps = 1/235 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+SD+ EQL K + EK R Q +E +L++ L+ +E + + Q + N++
Sbjct: 1148 ISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQI 1207
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQV-SQLSKIKVSLTTQLEDTKRL 376
+++ + ++ K+ + D L+ +AE++ ++ ++K + L + +
Sbjct: 1208 KAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQ 1267
Query: 377 ADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESE 556
R A + ++L+ L + + Q+++ DL+ ++ L +++ E E
Sbjct: 1268 LSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELE-E 1326
Query: 557 GVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
A E+ E +++ + L E E ++ L+ + +L K+++ ++ LQ EV+
Sbjct: 1327 LRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVE 1381
Score = 56.8 bits (131), Expect = 8e-08
Identities = 49/225 (21%), Positives = 100/225 (44%), Gaps = 6/225 (2%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+ ++ E+L+ +AK EK R+ E+ ++ L+ + Q ++ K+ + + ++
Sbjct: 754 IEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKM 813
Query: 200 QSKADEANRTLNDLDAAKKKLSIEN-SDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRL 376
+ +EA AA +K ++ ++L Q++ + +L K K +L+D
Sbjct: 814 RRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSN 873
Query: 377 ADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAE-AQLWRSKYES 553
++ + +A L R LE ++ R + EE DL Q +K E +L R E
Sbjct: 874 MEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEK 933
Query: 554 EGVARSEELEEAK----RKLQARLAEAEETIESLNQKVVALEKTK 676
E A +L K ++L+ + EE +++ N AL+ +
Sbjct: 934 E--ALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSAR 976
Score = 54.8 bits (126), Expect = 3e-07
Identities = 39/228 (17%), Positives = 98/228 (42%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
V D+ L+Q K++ E+ + + ++ + + L N+K ++ +K+ +LN +
Sbjct: 670 VDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNAL 729
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
++ ++ + L K+L +L +LE + +++ K++ L+ +LE+
Sbjct: 730 NARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERL 789
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEG 559
+E + + + E + +R +EE L K +A++ +
Sbjct: 790 EEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNL 849
Query: 560 VARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVED 703
++LE+ K + + L + +E + + LEK + L ++ +
Sbjct: 850 QRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNE 897
Score = 53.2 bits (122), Expect = 1e-06
Identities = 48/217 (22%), Positives = 90/217 (41%), Gaps = 1/217 (0%)
Frame = +2
Query: 74 EKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAK 253
E+ + + V+ L+ LD + + ++ K+++ LNE++ + ANR +
Sbjct: 1223 EQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQV 1282
Query: 254 KKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNL- 430
K L D QL++A L K +++ + + + EE R + R L
Sbjct: 1283 KSLQSLLKDTQIQLDDAVRANDDL-KENIAIVERRNNLLQAELEELRAVVEQTERSRKLA 1341
Query: 431 EHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQAR 610
E +L E+V+ L Q K +A+ +++ E E V EE +K
Sbjct: 1342 EQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVE-EAVQECRNAEEKAKKAITD 1400
Query: 611 LAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
A E ++ LE+ K+ + ++DLQ +D
Sbjct: 1401 AAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLD 1437
Score = 50.8 bits (116), Expect = 5e-06
Identities = 47/215 (21%), Positives = 104/215 (48%), Gaps = 8/215 (3%)
Frame = +2
Query: 101 EVNDLRAGLDHLSNEKAAQ-EKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENS 277
E N ++A ++ EK + E+ + ++ +Q+ D R+ N+ KKK+ + +
Sbjct: 1203 EFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLN 1262
Query: 278 DLLRQLEEAESQVSQLSKIKVSLTTQLEDTK-RL-----ADEEARERATLLGKFRN-LEH 436
++ QL A ++ K SL + L+DT+ +L A+++ +E ++ + N L+
Sbjct: 1263 EMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQA 1322
Query: 437 DLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLA 616
+L+ +R VE+ + +++L + + QL S+ S + + ++++ +LQ +
Sbjct: 1323 ELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSL-INQKKKMDADLSQLQTEVE 1381
Query: 617 EAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
EA + + +K +K A E+L+ E D
Sbjct: 1382 EAVQECRNAEEKA---KKAITDAAMMAEELKKEQD 1413
Score = 50.0 bits (114), Expect = 9e-06
Identities = 39/169 (23%), Positives = 80/169 (47%), Gaps = 2/169 (1%)
Frame = +2
Query: 29 MGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSN-EKAAQEKIVKQLQHQLNEVQS 205
M E+L + A E+ + + DL+ LD +K +++L+ ++ E+++
Sbjct: 1404 MAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEN 1463
Query: 206 KADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADE 385
+ + + + +K +L Q EE + +L + L +++ KR A+E
Sbjct: 1464 ELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEE 1523
Query: 386 EARERATLLGKFRNLEHDLDNIREQVEEEAEGKADL-QRQLSKANAEAQ 529
+ T L KFR ++H+LD EAE +AD+ + Q++K A+++
Sbjct: 1524 AEEQANTNLSKFRKVQHELD--------EAEERADIAESQVNKLRAKSR 1564
Score = 48.0 bits (109), Expect = 4e-05
Identities = 61/254 (24%), Positives = 117/254 (46%), Gaps = 21/254 (8%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+++M QL N++ A+A+K S + D + LD ++ + ++ + N +
Sbjct: 1261 LNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLL 1320
Query: 200 QSKADEANRTLNDLDAAKKKLS---IENSDLLRQLEEAE-SQVSQLSKIKVSLT---TQL 358
Q++ +E + + ++K IE S+ ++ L S ++Q K+ L+ T++
Sbjct: 1321 QAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEV 1380
Query: 359 EDTK---RLADEEARERAT---LLGKFRNLEHDLDNIREQVEEEAEGKA-DLQRQLSKAN 517
E+ R A+E+A++ T ++ + E D E++++ E DLQ +L +A
Sbjct: 1381 EEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAE 1440
Query: 518 AEAQLWRSKYESEGVARSEELE---EAKRKLQAR----LAEAEETIESLNQKVVALEKTK 676
A K + AR ELE EA++K A + ++E I+ L + K
Sbjct: 1441 QIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNL 1500
Query: 677 QRLATEVEDLQLEV 718
RL V+ LQL+V
Sbjct: 1501 LRLQDLVDKLQLKV 1514
Score = 47.6 bits (108), Expect = 5e-05
Identities = 51/234 (21%), Positives = 103/234 (44%), Gaps = 8/234 (3%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD 214
E L+ L K + + + E++DL L EK+ KQL+ + E+QS +
Sbjct: 1129 ESLEHLETFKRENKNLQ----EEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALE 1184
Query: 215 EANRTLNDLDAAKKKLSIE----NSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLAD 382
EA +L + + +E +++ R+L E + ++ Q + + + L+ + D
Sbjct: 1185 EAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTS---LD 1241
Query: 383 EEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGV 562
E R R L + +E DL+ + Q+ A+ Q+Q+ + + + + + + V
Sbjct: 1242 AETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLD-DAV 1300
Query: 563 ARSEELEE----AKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQL 712
+++L+E +R+ AE EE + Q + + +Q L E +QL
Sbjct: 1301 RANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQL 1354
Score = 43.2 bits (97), Expect = 0.001
Identities = 49/202 (24%), Positives = 88/202 (43%), Gaps = 13/202 (6%)
Frame = +2
Query: 143 EKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQ 322
E A+ ++ +L+ L + +++ E + L K L ++ L +AE + Q
Sbjct: 487 EMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQ 546
Query: 323 LSKIKVSLTTQ-------LEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEG 481
L K K+ L + LED E A L K R LE + ++ ++
Sbjct: 547 LIKNKIQLEAKVKEMNERLED-------EEEMNAELTAKKRKLEDECSELKRDID----- 594
Query: 482 KADLQRQLSKANAEAQLWRSKYE--SEGVARSEE----LEEAKRKLQARLAEAEETIESL 643
DL+ L+K E +K + +E +A +E L + K+ LQ +A + +++
Sbjct: 595 --DLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAE 652
Query: 644 NQKVVALEKTKQRLATEVEDLQ 709
KV L K K +L +V+DL+
Sbjct: 653 EDKVNTLTKAKVKLEQQVDDLE 674
Score = 30.7 bits (66), Expect = 6.2
Identities = 23/86 (26%), Positives = 45/86 (52%), Gaps = 3/86 (3%)
Frame = +2
Query: 455 EQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQAR---LAEAE 625
E+ +E A K + R L +A +++ R + E + V+ +E + + ++QA LA+AE
Sbjct: 483 EREKEMASMKEEFTR-LKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAE 541
Query: 626 ETIESLNQKVVALEKTKQRLATEVED 703
E + L + + LE + + +ED
Sbjct: 542 ERCDQLIKNKIQLEAKVKEMNERLED 567
>AY518538-1|AAT44534.1| 1179|Homo sapiens rhabdomyosarcoma antigen
MU-RMS-40.7B protein.
Length = 1179
Score = 233 bits (570), Expect = 5e-61
Identities = 110/235 (46%), Positives = 167/235 (71%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
V+++GEQ+D L ++K K EK ++++ E++D+ + ++ + KA EK+ + L+ Q+NE
Sbjct: 444 VAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEH 503
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
+SKA+E R++NDL + + KL EN +L RQL+E E+ +SQL++ K++ T QLED KR
Sbjct: 504 RSKAEETQRSVNDLTSQQAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQL 563
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEG 559
+EE + + L ++ HD D +REQ EEE E KA+LQR LSKAN+E WR+KYE++
Sbjct: 564 EEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDA 623
Query: 560 VARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
+ R+EELEEAK+KL RL EAEE +E++N K +LEKTK RL E+EDL ++V+R
Sbjct: 624 IQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVER 678
Score = 73.7 bits (173), Expect = 7e-13
Identities = 51/237 (21%), Positives = 109/237 (45%), Gaps = 1/237 (0%)
Frame = +2
Query: 14 RFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLN 193
R V + LD + + +A + + + ++N++ L H + A +K VK LQ L
Sbjct: 836 RVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLK 895
Query: 194 EVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKR 373
+ Q + D+A R +DL + N+ L +LEE + V Q + + +L +T
Sbjct: 896 DTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSE 955
Query: 374 LADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYES 553
+ +L+ + + ++ DL ++ +VEE + + + + KA +A + + +
Sbjct: 956 RVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKK 1015
Query: 554 EGVARSEELEEAKRKLQARLAEAEETIESLNQ-KVVALEKTKQRLATEVEDLQLEVD 721
E S LE K+ ++ + + + ++ Q + +K Q+L V +L+ E++
Sbjct: 1016 E-QDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELE 1071
Score = 70.1 bits (164), Expect = 8e-12
Identities = 59/235 (25%), Positives = 109/235 (46%), Gaps = 1/235 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+ D+ + D++N L K + + +V+DL L+ + E+ ++L+ L
Sbjct: 251 LDDLQAEEDKVNTLT----KAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLT 306
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
Q + LD KK E + L ++E+ ++ SQL K L ++E+ +
Sbjct: 307 QESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEEL 366
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKAN-AEAQLWRSKYESE 556
+ E RA + +L +L+ I E++EE A G +Q +++K AE Q R E E
Sbjct: 367 EAERTARAKVEKLRSDLSRELEEISERLEE-AGGATSVQIEMNKKREAEFQKMRRDLE-E 424
Query: 557 GVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
+ E A RK A +++ L +++ L++ KQ+L E + +LE+D
Sbjct: 425 ATLQHEATAAALRKKHA------DSVAELGEQIDNLQRVKQKLEKEKSEFKLELD 473
Score = 64.9 bits (151), Expect = 3e-10
Identities = 50/231 (21%), Positives = 103/231 (44%), Gaps = 1/231 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+ D+ QL++ K K + + LR + + KA ++++ + ++ +
Sbjct: 556 LEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQW 615
Query: 200 QSKAD-EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRL 376
++K + +A + +L+ AKKKL+ + +E ++ S L K K L ++ED
Sbjct: 616 RTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVD 675
Query: 377 ADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESE 556
+ A L K RN + L +++ EE Q++ + E ++ YE E
Sbjct: 676 VERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYE-E 734
Query: 557 GVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQ 709
+ E + + LQ +++ E + S + + LEK +++L E +LQ
Sbjct: 735 SLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQ 785
Score = 59.7 bits (138), Expect = 1e-08
Identities = 46/235 (19%), Positives = 110/235 (46%), Gaps = 1/235 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+SD+ EQL K + EK R Q +E +L++ L+ +E + + Q + N++
Sbjct: 753 ISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQI 812
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQV-SQLSKIKVSLTTQLEDTKRL 376
+++ + ++ K+ + D L+ +AE++ ++ ++K + L + +
Sbjct: 813 KAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQ 872
Query: 377 ADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESE 556
R A + ++L+ L + + Q+++ DL+ ++ L +++ E E
Sbjct: 873 LSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELE-E 931
Query: 557 GVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
A E+ E +++ + L E E ++ L+ + +L K+++ ++ LQ EV+
Sbjct: 932 LRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVE 986
Score = 56.8 bits (131), Expect = 8e-08
Identities = 49/225 (21%), Positives = 100/225 (44%), Gaps = 6/225 (2%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+ ++ E+L+ +AK EK R+ E+ ++ L+ + Q ++ K+ + + ++
Sbjct: 359 IEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKM 418
Query: 200 QSKADEANRTLNDLDAAKKKLSIEN-SDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRL 376
+ +EA AA +K ++ ++L Q++ + +L K K +L+D
Sbjct: 419 RRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSN 478
Query: 377 ADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAE-AQLWRSKYES 553
++ + +A L R LE ++ R + EE DL Q +K E +L R E
Sbjct: 479 MEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQQAKLQTENGELSRQLDEK 538
Query: 554 EGVARSEELEEAK----RKLQARLAEAEETIESLNQKVVALEKTK 676
E A +L K ++L+ + EE +++ N AL+ +
Sbjct: 539 E--ALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSAR 581
Score = 54.8 bits (126), Expect = 3e-07
Identities = 39/228 (17%), Positives = 98/228 (42%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
V D+ L+Q K++ E+ + + ++ + + L N+K ++ +K+ +LN +
Sbjct: 275 VDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNAL 334
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
++ ++ + L K+L +L +LE + +++ K++ L+ +LE+
Sbjct: 335 NARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERL 394
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEG 559
+E + + + E + +R +EE L K +A++ +
Sbjct: 395 EEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNL 454
Query: 560 VARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVED 703
++LE+ K + + L + +E + + LEK + L ++ +
Sbjct: 455 QRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNE 502
Score = 53.2 bits (122), Expect = 1e-06
Identities = 48/217 (22%), Positives = 90/217 (41%), Gaps = 1/217 (0%)
Frame = +2
Query: 74 EKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAK 253
E+ + + V+ L+ LD + + ++ K+++ LNE++ + ANR +
Sbjct: 828 EQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQV 887
Query: 254 KKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNL- 430
K L D QL++A L K +++ + + + EE R + R L
Sbjct: 888 KSLQSLLKDTQIQLDDAVRANDDL-KENIAIVERRNNLLQAELEELRAVVEQTERSRKLA 946
Query: 431 EHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQAR 610
E +L E+V+ L Q K +A+ +++ E E V EE +K
Sbjct: 947 EQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVE-EAVQECRNAEEKAKKAITD 1005
Query: 611 LAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
A E ++ LE+ K+ + ++DLQ +D
Sbjct: 1006 AAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLD 1042
Score = 50.8 bits (116), Expect = 5e-06
Identities = 47/215 (21%), Positives = 104/215 (48%), Gaps = 8/215 (3%)
Frame = +2
Query: 101 EVNDLRAGLDHLSNEKAAQ-EKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENS 277
E N ++A ++ EK + E+ + ++ +Q+ D R+ N+ KKK+ + +
Sbjct: 808 EFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLN 867
Query: 278 DLLRQLEEAESQVSQLSKIKVSLTTQLEDTK-RL-----ADEEARERATLLGKFRN-LEH 436
++ QL A ++ K SL + L+DT+ +L A+++ +E ++ + N L+
Sbjct: 868 EMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQA 927
Query: 437 DLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLA 616
+L+ +R VE+ + +++L + + QL S+ S + + ++++ +LQ +
Sbjct: 928 ELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSL-INQKKKMDADLSQLQTEVE 986
Query: 617 EAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
EA + + +K +K A E+L+ E D
Sbjct: 987 EAVQECRNAEEKA---KKAITDAAMMAEELKKEQD 1018
Score = 50.0 bits (114), Expect = 9e-06
Identities = 39/169 (23%), Positives = 80/169 (47%), Gaps = 2/169 (1%)
Frame = +2
Query: 29 MGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSN-EKAAQEKIVKQLQHQLNEVQS 205
M E+L + A E+ + + DL+ LD +K +++L+ ++ E+++
Sbjct: 1009 MAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEN 1068
Query: 206 KADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADE 385
+ + + + +K +L Q EE + +L + L +++ KR A+E
Sbjct: 1069 ELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEE 1128
Query: 386 EARERATLLGKFRNLEHDLDNIREQVEEEAEGKADL-QRQLSKANAEAQ 529
+ T L KFR ++H+LD EAE +AD+ + Q++K A+++
Sbjct: 1129 AEEQANTNLSKFRKVQHELD--------EAEERADIAESQVNKLRAKSR 1169
Score = 48.0 bits (109), Expect = 4e-05
Identities = 61/254 (24%), Positives = 117/254 (46%), Gaps = 21/254 (8%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+++M QL N++ A+A+K S + D + LD ++ + ++ + N +
Sbjct: 866 LNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLL 925
Query: 200 QSKADEANRTLNDLDAAKKKLS---IENSDLLRQLEEAE-SQVSQLSKIKVSLT---TQL 358
Q++ +E + + ++K IE S+ ++ L S ++Q K+ L+ T++
Sbjct: 926 QAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEV 985
Query: 359 EDTK---RLADEEARERAT---LLGKFRNLEHDLDNIREQVEEEAEGKA-DLQRQLSKAN 517
E+ R A+E+A++ T ++ + E D E++++ E DLQ +L +A
Sbjct: 986 EEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAE 1045
Query: 518 AEAQLWRSKYESEGVARSEELE---EAKRKLQAR----LAEAEETIESLNQKVVALEKTK 676
A K + AR ELE EA++K A + ++E I+ L + K
Sbjct: 1046 QIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNL 1105
Query: 677 QRLATEVEDLQLEV 718
RL V+ LQL+V
Sbjct: 1106 LRLQDLVDKLQLKV 1119
Score = 47.6 bits (108), Expect = 5e-05
Identities = 51/234 (21%), Positives = 103/234 (44%), Gaps = 8/234 (3%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD 214
E L+ L K + + + E++DL L EK+ KQL+ + E+QS +
Sbjct: 734 ESLEHLETFKRENKNLQ----EEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALE 789
Query: 215 EANRTLNDLDAAKKKLSIE----NSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLAD 382
EA +L + + +E +++ R+L E + ++ Q + + + L+ + D
Sbjct: 790 EAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTS---LD 846
Query: 383 EEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGV 562
E R R L + +E DL+ + Q+ A+ Q+Q+ + + + + + + V
Sbjct: 847 AETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLD-DAV 905
Query: 563 ARSEELEE----AKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQL 712
+++L+E +R+ AE EE + Q + + +Q L E +QL
Sbjct: 906 RANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQL 959
Score = 43.2 bits (97), Expect = 0.001
Identities = 49/202 (24%), Positives = 88/202 (43%), Gaps = 13/202 (6%)
Frame = +2
Query: 143 EKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQ 322
E A+ ++ +L+ L + +++ E + L K L ++ L +AE + Q
Sbjct: 92 EMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQ 151
Query: 323 LSKIKVSLTTQ-------LEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEG 481
L K K+ L + LED E A L K R LE + ++ ++
Sbjct: 152 LIKNKIQLEAKVKEMNERLED-------EEEMNAELTAKKRKLEDECSELKRDID----- 199
Query: 482 KADLQRQLSKANAEAQLWRSKYE--SEGVARSEE----LEEAKRKLQARLAEAEETIESL 643
DL+ L+K E +K + +E +A +E L + K+ LQ +A + +++
Sbjct: 200 --DLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAE 257
Query: 644 NQKVVALEKTKQRLATEVEDLQ 709
KV L K K +L +V+DL+
Sbjct: 258 EDKVNTLTKAKVKLEQQVDDLE 279
Score = 30.7 bits (66), Expect = 6.2
Identities = 23/86 (26%), Positives = 45/86 (52%), Gaps = 3/86 (3%)
Frame = +2
Query: 455 EQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQAR---LAEAE 625
E+ +E A K + R L +A +++ R + E + V+ +E + + ++QA LA+AE
Sbjct: 88 EREKEMASMKEEFTR-LKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAE 146
Query: 626 ETIESLNQKVVALEKTKQRLATEVED 703
E + L + + LE + + +ED
Sbjct: 147 ERCDQLIKNKIQLEAKVKEMNERLED 172
>Z20656-1|CAA79675.1| 1939|Homo sapiens cardiac alpha-myosin heavy
chain protein.
Length = 1939
Score = 231 bits (564), Expect = 3e-60
Identities = 109/235 (46%), Positives = 163/235 (69%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
V+++GEQ+D L ++K K EK ++++ E++D+ + ++ + KA EK+ + L+ Q NE
Sbjct: 1202 VAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEY 1261
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
+ K +EA R+LND + KL EN +L RQLEE E+ +SQL++ K+S T Q+ED KR
Sbjct: 1262 RVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQL 1321
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEG 559
+EE + + L ++ HD D +REQ EEE E KA+LQR LSKAN+E WR+KYE++
Sbjct: 1322 EEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDA 1381
Query: 560 VARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
+ R+EELEEAK+KL RL +AEE +E++N K +LEKTK RL E+EDL ++V+R
Sbjct: 1382 IQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVER 1436
Score = 73.3 bits (172), Expect = 9e-13
Identities = 51/237 (21%), Positives = 108/237 (45%), Gaps = 1/237 (0%)
Frame = +2
Query: 14 RFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLN 193
R V + LD + + + + + + ++N++ L H + A +K VK LQ L
Sbjct: 1594 RVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLK 1653
Query: 194 EVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKR 373
+ Q + D+A R +DL + N+ L +LEE + V Q + + +L +T
Sbjct: 1654 DTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSE 1713
Query: 374 LADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYES 553
+ +L+ + + +E DL ++ +VEE + + + + KA +A + + +
Sbjct: 1714 RVQLLHSQNTSLINQKKKMESDLTQLQSEVEEAVQECRNAEEKAKKAITDAAMMAEELKK 1773
Query: 554 EGVARSEELEEAKRKLQARLAEAEETIESLNQ-KVVALEKTKQRLATEVEDLQLEVD 721
E S LE K+ ++ + + + ++ Q + +K Q+L V +L+ E++
Sbjct: 1774 E-QDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEGELE 1829
Score = 66.5 bits (155), Expect = 1e-10
Identities = 53/233 (22%), Positives = 105/233 (45%), Gaps = 1/233 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+ D+ QL++ K K + + LR + + KA ++++ + ++ +
Sbjct: 1314 MEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQW 1373
Query: 200 QSKAD-EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRL 376
++K + +A + +L+ AKKKL+ D +E ++ S L K K L ++ED
Sbjct: 1374 RTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVD 1433
Query: 377 ADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESE 556
+ A L K RN + L +++ EE Q++ + E ++ YE E
Sbjct: 1434 VERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYE-E 1492
Query: 557 GVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLE 715
+ E + + LQ +++ E + + V LEK +++L EVE L+L+
Sbjct: 1493 SLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKVRKQL--EVEKLELQ 1543
Score = 60.5 bits (140), Expect = 7e-09
Identities = 53/238 (22%), Positives = 111/238 (46%), Gaps = 9/238 (3%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQ-EKIVKQLQHQLNEVQSKA 211
EQ ++ + KA+ ++ ++ SEV R + + ++ + E+ K+L +L + +
Sbjct: 1347 EQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAV 1406
Query: 212 DEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEA 391
+ N + L+ K +L E DL+ +E + + + L K + + L + K+ +E
Sbjct: 1407 EAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQ 1466
Query: 392 RERATLLGKFRNLEHDLDNIREQVEEEAEG-------KADLQRQLSKANAE-AQLWRSKY 547
E + + R+L +L ++ EE E +LQ ++S + + ++ +
Sbjct: 1467 SELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVH 1526
Query: 548 ESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
E E V + E+E K +LQ+ L EAE ++E K++ + ++ E+E E D
Sbjct: 1527 ELEKVRKQLEVE--KLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKD 1582
Score = 58.8 bits (136), Expect = 2e-08
Identities = 51/216 (23%), Positives = 103/216 (47%), Gaps = 9/216 (4%)
Frame = +2
Query: 101 EVNDLRAGLDHLSNEKAAQ-EKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKK------ 259
E N ++A ++ EK + E+ + Q ++ +Q+ D R+ N++ KKK
Sbjct: 1566 EFNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLN 1625
Query: 260 -LSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRN-LE 433
+ I+ S R EA+ QV L + QL+D R A+++ +E ++ + N L+
Sbjct: 1626 EMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVR-ANDDLKENIAIVERRNNLLQ 1684
Query: 434 HDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARL 613
+L+ +R VE+ + +++L + + QL S+ S + + +++E +LQ+ +
Sbjct: 1685 AELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSL-INQKKKMESDLTQLQSEV 1743
Query: 614 AEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
EA + + +K +K A E+L+ E D
Sbjct: 1744 EEAVQECRNAEEKA---KKAITDAAMMAEELKKEQD 1776
Score = 56.0 bits (129), Expect = 1e-07
Identities = 41/233 (17%), Positives = 102/233 (43%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+ D E ++ +N + EK + + +E+ DL ++ + AA +K + L E
Sbjct: 1399 LQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEW 1458
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
+ K +E+ L + LS E L EE+ + + +L ++ D
Sbjct: 1459 KQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQL 1518
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEG 559
E + L + LE + ++ +EE + ++ +A E +++ E +
Sbjct: 1519 GEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKL 1578
Query: 560 VARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEV 718
+ EE+E+AKR Q + + ++++ + + + K+++ ++ ++++++
Sbjct: 1579 AEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQL 1631
Score = 53.2 bits (122), Expect = 1e-06
Identities = 68/267 (25%), Positives = 121/267 (45%), Gaps = 32/267 (11%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVK---QLQHQL 190
V ++ E++ L+++ AK K + + E + + LD L E+ + K +L+ Q+
Sbjct: 977 VKNLTEEMAGLDEIIAKLTKEK-KALQEAH--QQALDDLQVEEDKVNSLSKSKVKLEQQV 1033
Query: 191 NEVQSKADEANRTLNDLDAAKKKL------------SIENS--DLLRQLEEAESQVSQL- 325
++++ ++ + DL+ AK+KL +EN L +L++ E ++Q
Sbjct: 1034 DDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQN 1093
Query: 326 SKIKVSLTTQLEDTKRLADEEAR---------ERATLLGKFRNLEHDLDNIREQVE---E 469
SKI+ L+ K+L + +AR T K L DL E++ E
Sbjct: 1094 SKIEDEQALALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLE 1153
Query: 470 EAEGKADLQRQLS-KANAEAQLWRSKYESEGVARSEELEEAKRKLQA-RLAEAEETIESL 643
EA G +Q +++ K AE Q R E E + E A RK A +AE E I++L
Sbjct: 1154 EAGGATSVQIEMNKKREAEFQKMRRDLE-EATLQHEATAAALRKKHADSVAELGEQIDNL 1212
Query: 644 NQKVVALEKTKQRLATEVEDLQLEVDR 724
+ LEK K E++D+ +++
Sbjct: 1213 QRVKQKLEKEKSEFKLELDDVTSNMEQ 1239
Score = 50.8 bits (116), Expect = 5e-06
Identities = 48/217 (22%), Positives = 89/217 (41%), Gaps = 1/217 (0%)
Frame = +2
Query: 74 EKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAK 253
E+ + + V+ L+ LD + + ++ K+++ LNE++ + ANR +
Sbjct: 1586 EQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQV 1645
Query: 254 KKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNL- 430
K L D QL++A L K +++ + + + EE R + R L
Sbjct: 1646 KSLQSLLKDTQIQLDDAVRANDDL-KENIAIVERRNNLLQAELEELRAVVEQTERSRKLA 1704
Query: 431 EHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQAR 610
E +L E+V+ L Q K ++ +S+ E E V EE +K
Sbjct: 1705 EQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQSEVE-EAVQECRNAEEKAKKAITD 1763
Query: 611 LAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
A E ++ LE+ K+ + ++DLQ +D
Sbjct: 1764 AAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLD 1800
Score = 50.4 bits (115), Expect = 7e-06
Identities = 65/257 (25%), Positives = 119/257 (46%), Gaps = 24/257 (9%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDH-------LSNEKAAQEKIVKQL 178
+++M QL N++ A+A+K S + D + LD L A E+ L
Sbjct: 1624 LNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLL 1683
Query: 179 QHQLNEVQSKADEANRT-------LNDLDAAKKKLSIENSDLLRQLEEAESQVSQL-SKI 334
Q +L E+++ ++ R+ L + + L +N+ L+ Q ++ ES ++QL S++
Sbjct: 1684 QAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQSEV 1743
Query: 335 K--VSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLS 508
+ V E+ + A +A A L K ++ L+ +++ +E+ + DLQ +L
Sbjct: 1744 EEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIK---DLQHRLD 1800
Query: 509 KANAEAQLWRSKYESEGVARSEELE---EAKRKLQAR----LAEAEETIESLNQKVVALE 667
+A A K + AR ELE EA++K A + ++E I+ L + +
Sbjct: 1801 EAEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDK 1860
Query: 668 KTKQRLATEVEDLQLEV 718
K RL V+ LQL+V
Sbjct: 1861 KNLLRLQDLVDKLQLKV 1877
Score = 50.0 bits (114), Expect = 9e-06
Identities = 39/169 (23%), Positives = 80/169 (47%), Gaps = 2/169 (1%)
Frame = +2
Query: 29 MGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSN-EKAAQEKIVKQLQHQLNEVQS 205
M E+L + A E+ + + DL+ LD +K +++L+ ++ E++
Sbjct: 1767 MAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEG 1826
Query: 206 KADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADE 385
+ + + + +K +L Q EE + + +L + L +++ KR A+E
Sbjct: 1827 ELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLLRLQDLVDKLQLKVKAYKRQAEE 1886
Query: 386 EARERATLLGKFRNLEHDLDNIREQVEEEAEGKADL-QRQLSKANAEAQ 529
+ T L KFR ++H+LD EAE +AD+ + Q++K A+++
Sbjct: 1887 AEEQANTNLSKFRKVQHELD--------EAEERADIAESQVNKLRAKSR 1927
Score = 42.3 bits (95), Expect = 0.002
Identities = 48/202 (23%), Positives = 89/202 (44%), Gaps = 13/202 (6%)
Frame = +2
Query: 143 EKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQ 322
E A ++ +++ L + +++ E + L K L ++ L +AE + Q
Sbjct: 850 EMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEERCDQ 909
Query: 323 LSKIKVSLTTQ-------LEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEG 481
L K K+ L + LED E A L K R LE + +++ ++
Sbjct: 910 LIKNKIQLEAKVKEMNERLED-------EEEMNAELTAKKRKLEDECSELKKDID----- 957
Query: 482 KADLQRQLSKANAEAQLWRSKYE--SEGVARSEE----LEEAKRKLQARLAEAEETIESL 643
DL+ L+K E +K + +E +A +E L + K+ LQ +A + ++
Sbjct: 958 --DLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVE 1015
Query: 644 NQKVVALEKTKQRLATEVEDLQ 709
KV +L K+K +L +V+DL+
Sbjct: 1016 EDKVNSLSKSKVKLEQQVDDLE 1037
>BC132667-1|AAI32668.1| 1939|Homo sapiens myosin, heavy chain 6,
cardiac muscle, alpha (cardiomyopathy, hypertrophic 1)
protein.
Length = 1939
Score = 231 bits (564), Expect = 3e-60
Identities = 109/235 (46%), Positives = 163/235 (69%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
V+++GEQ+D L ++K K EK ++++ E++D+ + ++ + KA EK+ + L+ Q NE
Sbjct: 1202 VAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEY 1261
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
+ K +EA R+LND + KL EN +L RQLEE E+ +SQL++ K+S T Q+ED KR
Sbjct: 1262 RVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQL 1321
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEG 559
+EE + + L ++ HD D +REQ EEE E KA+LQR LSKAN+E WR+KYE++
Sbjct: 1322 EEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDA 1381
Query: 560 VARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
+ R+EELEEAK+KL RL +AEE +E++N K +LEKTK RL E+EDL ++V+R
Sbjct: 1382 IQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVER 1436
Score = 73.3 bits (172), Expect = 9e-13
Identities = 51/237 (21%), Positives = 108/237 (45%), Gaps = 1/237 (0%)
Frame = +2
Query: 14 RFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLN 193
R V + LD + + + + + + ++N++ L H + A +K VK LQ L
Sbjct: 1594 RVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLK 1653
Query: 194 EVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKR 373
+ Q + D+A R +DL + N+ L +LEE + V Q + + +L +T
Sbjct: 1654 DTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSE 1713
Query: 374 LADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYES 553
+ +L+ + + +E DL ++ +VEE + + + + KA +A + + +
Sbjct: 1714 RVQLLHSQNTSLINQKKKMESDLTQLQSEVEEAVQECRNAEEKAKKAITDAAMMAEELKK 1773
Query: 554 EGVARSEELEEAKRKLQARLAEAEETIESLNQ-KVVALEKTKQRLATEVEDLQLEVD 721
E S LE K+ ++ + + + ++ Q + +K Q+L V +L+ E++
Sbjct: 1774 E-QDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEGELE 1829
Score = 66.5 bits (155), Expect = 1e-10
Identities = 53/233 (22%), Positives = 105/233 (45%), Gaps = 1/233 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+ D+ QL++ K K + + LR + + KA ++++ + ++ +
Sbjct: 1314 MEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQW 1373
Query: 200 QSKAD-EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRL 376
++K + +A + +L+ AKKKL+ D +E ++ S L K K L ++ED
Sbjct: 1374 RTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVD 1433
Query: 377 ADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESE 556
+ A L K RN + L +++ EE Q++ + E ++ YE E
Sbjct: 1434 VERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYE-E 1492
Query: 557 GVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLE 715
+ E + + LQ +++ E + + V LEK +++L EVE L+L+
Sbjct: 1493 SLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKVRKQL--EVEKLELQ 1543
Score = 60.5 bits (140), Expect = 7e-09
Identities = 53/238 (22%), Positives = 111/238 (46%), Gaps = 9/238 (3%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQ-EKIVKQLQHQLNEVQSKA 211
EQ ++ + KA+ ++ ++ SEV R + + ++ + E+ K+L +L + +
Sbjct: 1347 EQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAV 1406
Query: 212 DEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEA 391
+ N + L+ K +L E DL+ +E + + + L K + + L + K+ +E
Sbjct: 1407 EAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQ 1466
Query: 392 RERATLLGKFRNLEHDLDNIREQVEEEAEG-------KADLQRQLSKANAE-AQLWRSKY 547
E + + R+L +L ++ EE E +LQ ++S + + ++ +
Sbjct: 1467 SELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVH 1526
Query: 548 ESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
E E V + E+E K +LQ+ L EAE ++E K++ + ++ E+E E D
Sbjct: 1527 ELEKVRKQLEVE--KLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKD 1582
Score = 58.8 bits (136), Expect = 2e-08
Identities = 51/216 (23%), Positives = 103/216 (47%), Gaps = 9/216 (4%)
Frame = +2
Query: 101 EVNDLRAGLDHLSNEKAAQ-EKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKK------ 259
E N ++A ++ EK + E+ + Q ++ +Q+ D R+ N++ KKK
Sbjct: 1566 EFNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLN 1625
Query: 260 -LSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRN-LE 433
+ I+ S R EA+ QV L + QL+D R A+++ +E ++ + N L+
Sbjct: 1626 EMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVR-ANDDLKENIAIVERRNNLLQ 1684
Query: 434 HDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARL 613
+L+ +R VE+ + +++L + + QL S+ S + + +++E +LQ+ +
Sbjct: 1685 AELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSL-INQKKKMESDLTQLQSEV 1743
Query: 614 AEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
EA + + +K +K A E+L+ E D
Sbjct: 1744 EEAVQECRNAEEKA---KKAITDAAMMAEELKKEQD 1776
Score = 56.0 bits (129), Expect = 1e-07
Identities = 41/233 (17%), Positives = 102/233 (43%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+ D E ++ +N + EK + + +E+ DL ++ + AA +K + L E
Sbjct: 1399 LQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEW 1458
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
+ K +E+ L + LS E L EE+ + + +L ++ D
Sbjct: 1459 KQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQL 1518
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEG 559
E + L + LE + ++ +EE + ++ +A E +++ E +
Sbjct: 1519 GEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKL 1578
Query: 560 VARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEV 718
+ EE+E+AKR Q + + ++++ + + + K+++ ++ ++++++
Sbjct: 1579 AEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQL 1631
Score = 53.2 bits (122), Expect = 1e-06
Identities = 68/267 (25%), Positives = 121/267 (45%), Gaps = 32/267 (11%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVK---QLQHQL 190
V ++ E++ L+++ AK K + + E + + LD L E+ + K +L+ Q+
Sbjct: 977 VKNLTEEMAGLDEIIAKLTKEK-KALQEAH--QQALDDLQVEEDKVNSLSKSKVKLEQQV 1033
Query: 191 NEVQSKADEANRTLNDLDAAKKKL------------SIENS--DLLRQLEEAESQVSQL- 325
++++ ++ + DL+ AK+KL +EN L +L++ E ++Q
Sbjct: 1034 DDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQN 1093
Query: 326 SKIKVSLTTQLEDTKRLADEEAR---------ERATLLGKFRNLEHDLDNIREQVE---E 469
SKI+ L+ K+L + +AR T K L DL E++ E
Sbjct: 1094 SKIEDEQVLALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLE 1153
Query: 470 EAEGKADLQRQLS-KANAEAQLWRSKYESEGVARSEELEEAKRKLQA-RLAEAEETIESL 643
EA G +Q +++ K AE Q R E E + E A RK A +AE E I++L
Sbjct: 1154 EAGGATSVQIEMNKKREAEFQKMRRDLE-EATLQHEATAAALRKKHADSVAELGEQIDNL 1212
Query: 644 NQKVVALEKTKQRLATEVEDLQLEVDR 724
+ LEK K E++D+ +++
Sbjct: 1213 QRVKQKLEKEKSEFKLELDDVTSNMEQ 1239
Score = 50.8 bits (116), Expect = 5e-06
Identities = 48/217 (22%), Positives = 89/217 (41%), Gaps = 1/217 (0%)
Frame = +2
Query: 74 EKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAK 253
E+ + + V+ L+ LD + + ++ K+++ LNE++ + ANR +
Sbjct: 1586 EQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQV 1645
Query: 254 KKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNL- 430
K L D QL++A L K +++ + + + EE R + R L
Sbjct: 1646 KSLQSLLKDTQIQLDDAVRANDDL-KENIAIVERRNNLLQAELEELRAVVEQTERSRKLA 1704
Query: 431 EHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQAR 610
E +L E+V+ L Q K ++ +S+ E E V EE +K
Sbjct: 1705 EQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQSEVE-EAVQECRNAEEKAKKAITD 1763
Query: 611 LAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
A E ++ LE+ K+ + ++DLQ +D
Sbjct: 1764 AAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLD 1800
Score = 50.4 bits (115), Expect = 7e-06
Identities = 65/257 (25%), Positives = 119/257 (46%), Gaps = 24/257 (9%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDH-------LSNEKAAQEKIVKQL 178
+++M QL N++ A+A+K S + D + LD L A E+ L
Sbjct: 1624 LNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLL 1683
Query: 179 QHQLNEVQSKADEANRT-------LNDLDAAKKKLSIENSDLLRQLEEAESQVSQL-SKI 334
Q +L E+++ ++ R+ L + + L +N+ L+ Q ++ ES ++QL S++
Sbjct: 1684 QAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQSEV 1743
Query: 335 K--VSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLS 508
+ V E+ + A +A A L K ++ L+ +++ +E+ + DLQ +L
Sbjct: 1744 EEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIK---DLQHRLD 1800
Query: 509 KANAEAQLWRSKYESEGVARSEELE---EAKRKLQAR----LAEAEETIESLNQKVVALE 667
+A A K + AR ELE EA++K A + ++E I+ L + +
Sbjct: 1801 EAEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDK 1860
Query: 668 KTKQRLATEVEDLQLEV 718
K RL V+ LQL+V
Sbjct: 1861 KNLLRLQDLVDKLQLKV 1877
Score = 50.0 bits (114), Expect = 9e-06
Identities = 39/169 (23%), Positives = 80/169 (47%), Gaps = 2/169 (1%)
Frame = +2
Query: 29 MGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSN-EKAAQEKIVKQLQHQLNEVQS 205
M E+L + A E+ + + DL+ LD +K +++L+ ++ E++
Sbjct: 1767 MAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEG 1826
Query: 206 KADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADE 385
+ + + + +K +L Q EE + + +L + L +++ KR A+E
Sbjct: 1827 ELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLLRLQDLVDKLQLKVKAYKRQAEE 1886
Query: 386 EARERATLLGKFRNLEHDLDNIREQVEEEAEGKADL-QRQLSKANAEAQ 529
+ T L KFR ++H+LD EAE +AD+ + Q++K A+++
Sbjct: 1887 AEEQANTNLSKFRKVQHELD--------EAEERADIAESQVNKLRAKSR 1927
Score = 49.2 bits (112), Expect = 2e-05
Identities = 49/205 (23%), Positives = 94/205 (45%), Gaps = 17/205 (8%)
Frame = +2
Query: 140 NEKAAQEKIVK-QLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQV 316
N K E+++ QLQ +L E Q++ +E L A+ K+ SDL R+LEE ++
Sbjct: 1093 NSKIEDEQVLALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERL 1152
Query: 317 SQLS-----KIKVSLTTQLEDTKRLAD-EEA--RERATLLGKFRNLEHDLDNIREQVEEE 472
+ +I+++ + E K D EEA + AT + + + EQ++
Sbjct: 1153 EEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNL 1212
Query: 473 AEGKADLQRQLSKANAE--------AQLWRSKYESEGVARSEELEEAKRKLQARLAEAEE 628
K L+++ S+ E Q+ ++K E V+R+ LE+ + + +L EA+
Sbjct: 1213 QRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRT--LEDQANEYRVKLEEAQR 1270
Query: 629 TIESLNQKVVALEKTKQRLATEVED 703
++ + L+ LA ++E+
Sbjct: 1271 SLNDFTTQRAKLQTENGELARQLEE 1295
Score = 42.3 bits (95), Expect = 0.002
Identities = 48/202 (23%), Positives = 89/202 (44%), Gaps = 13/202 (6%)
Frame = +2
Query: 143 EKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQ 322
E A ++ +++ L + +++ E + L K L ++ L +AE + Q
Sbjct: 850 EMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEERCDQ 909
Query: 323 LSKIKVSLTTQ-------LEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEG 481
L K K+ L + LED E A L K R LE + +++ ++
Sbjct: 910 LIKNKIQLEAKVKEMNERLED-------EEEMNAELTAKKRKLEDECSELKKDID----- 957
Query: 482 KADLQRQLSKANAEAQLWRSKYE--SEGVARSEE----LEEAKRKLQARLAEAEETIESL 643
DL+ L+K E +K + +E +A +E L + K+ LQ +A + ++
Sbjct: 958 --DLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVE 1015
Query: 644 NQKVVALEKTKQRLATEVEDLQ 709
KV +L K+K +L +V+DL+
Sbjct: 1016 EDKVNSLSKSKVKLEQQVDDLE 1037
>AF111783-1|AAD29949.1| 1939|Homo sapiens myosin heavy chain IIb
protein.
Length = 1939
Score = 231 bits (564), Expect = 3e-60
Identities = 108/235 (45%), Positives = 167/235 (71%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
V+++G+Q+D L ++K K EK +++ E+NDL + ++ +S KA EK+ + L+ QL+E+
Sbjct: 1204 VAELGKQIDSLQRVKQKLEKEKSELKMEINDLASNMETVSKAKANFEKMCRTLEDQLSEI 1263
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
++K +E R +N+L A K +L E+ + RQL+E ++ VSQLS+ K + T Q+E+ KR
Sbjct: 1264 KTKEEEQQRLINELSAQKARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEELKRQL 1323
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEG 559
+EE + ++TL ++ HD D +REQ EEE E KA+LQR +SKAN+E WR+KYE++
Sbjct: 1324 EEETKAKSTLAHALQSARHDCDLLREQYEEEQEAKAELQRGMSKANSEVAQWRTKYETDA 1383
Query: 560 VARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
+ R+EELEEAK+KL RL +AEE +E++N K +LEKTKQRL EVEDL ++V+R
Sbjct: 1384 IQRTEELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVER 1438
Score = 62.9 bits (146), Expect = 1e-09
Identities = 49/231 (21%), Positives = 103/231 (44%), Gaps = 1/231 (0%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQ-EKIVKQLQHQLNEVQSKA 211
EQ ++ + KA+ ++ ++ SEV R + + ++ + E+ K+L +L + +
Sbjct: 1349 EQYEEEQEAKAELQRGMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHV 1408
Query: 212 DEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEA 391
+ N L+ K++L E DL+ +E + + L K + + L + K+ +E
Sbjct: 1409 EAVNSKCASLEKTKQRLQNEVEDLMIDVERSNAACIALDKKQRNFDKVLAEWKQKYEETQ 1468
Query: 392 RERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARS 571
E + R+L +L ++ EE + L+R+ E + +EG
Sbjct: 1469 AELEASQKESRSLSTELFKVKNAYEESLDHLETLKRENKNLQQEISDLTEQI-AEGGKHI 1527
Query: 572 EELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
ELE+ K++L +E + ++E + E R+ E+ ++ E+DR
Sbjct: 1528 HELEKVKKQLDHEKSELQTSLEEAEASLEHEEGKILRIQLELNQVKSEIDR 1578
Score = 60.5 bits (140), Expect = 7e-09
Identities = 47/219 (21%), Positives = 109/219 (49%), Gaps = 3/219 (1%)
Frame = +2
Query: 74 EKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAK 253
E+ + + + D ++ ++++ A+ EK ++LQ+++ ++ + +N LD +
Sbjct: 1391 EEAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERSNAACIALDKKQ 1450
Query: 254 KKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLE 433
+ ++ ++ EE ++++ K SL+T+L K +E TL + +NL+
Sbjct: 1451 RNFDKVLAEWKQKYEETQAELEASQKESRSLSTELFKVKNAYEESLDHLETLKRENKNLQ 1510
Query: 434 HDLDNIREQVEEEAEGKADLQRQLSKANAE-AQLWRSKYESEGVARSEELEEAK-RKLQA 607
++ ++ EQ+ E + +L++ + + E ++L S E+E S E EE K ++Q
Sbjct: 1511 QEISDLTEQIAEGGKHIHELEKVKKQLDHEKSELQTSLEEAEA---SLEHEEGKILRIQL 1567
Query: 608 RLAEAEETIE-SLNQKVVALEKTKQRLATEVEDLQLEVD 721
L + + I+ + +K L++ K+ VE +Q +D
Sbjct: 1568 ELNQVKSEIDRKIAEKDEELDQLKRNHLRVVESMQSTLD 1606
Score = 59.7 bits (138), Expect = 1e-08
Identities = 50/239 (20%), Positives = 106/239 (44%), Gaps = 7/239 (2%)
Frame = +2
Query: 14 RFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLN 193
R V M LD + + A + + + ++N++ L+H + + A + ++ Q L
Sbjct: 1596 RVVESMQSTLDAEIRSRNDALRIKKKMEGDLNEMEIQLNHANRQAAEALRNLRNTQGILK 1655
Query: 194 EVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKR 373
+ Q D+A R +DL + + + ++EE + + + + + +L D
Sbjct: 1656 DTQLHLDDAIRGQDDLKEQLAMVERRANLMQAEVEELRASLERTERGRKMAEQELLDASE 1715
Query: 374 LADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRS--KY 547
+ +L+ + LE D+ I+ ++E+ + + + + KA +A + K
Sbjct: 1716 RVQLLHTQNTSLINTKKKLETDISQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKK 1775
Query: 548 ESEGVARSE----ELEEAKRKLQARLAEAEE-TIESLNQKVVALEKTKQRLATEVEDLQ 709
E + A E +E+ + LQ RL EAE+ ++ +++ LE + L +EVE Q
Sbjct: 1776 EQDTSAHLERMKKNMEQTVKDLQLRLGEAEQLALKGGKKQIQKLEARVRELESEVESEQ 1834
Score = 59.3 bits (137), Expect = 2e-08
Identities = 46/235 (19%), Positives = 104/235 (44%), Gaps = 1/235 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
V D+ +++ N +K + + + + + + E A +K + L +L +V
Sbjct: 1429 VEDLMIDVERSNAACIALDKKQRNFDKVLAEWKQKYEETQAELEASQKESRSLSTELFKV 1488
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
++ +E+ L L K L E SDL Q+ E + +L K+K L + + +
Sbjct: 1489 KNAYEESLDHLETLKRENKNLQQEISDLTEQIAEGGKHIHELEKVKKQLDHEKSELQTSL 1548
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAE-AQLWRSKYESE 556
+E GK ++ +L+ ++ +++ + K + QL + + + +S ++E
Sbjct: 1549 EEAEASLEHEEGKILRIQLELNQVKSEIDRKIAEKDEELDQLKRNHLRVVESMQSTLDAE 1608
Query: 557 GVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
+R++ L K+K++ L E E + N++ + + ++D QL +D
Sbjct: 1609 IRSRNDAL-RIKKKMEGDLNEMEIQLNHANRQAAEALRNLRNTQGILKDTQLHLD 1662
Score = 58.0 bits (134), Expect = 4e-08
Identities = 50/235 (21%), Positives = 108/235 (45%), Gaps = 1/235 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
++D E+ DQL K K + E EV + + ++ E A+++ +L+ + +E+
Sbjct: 902 LADAEERCDQLIKTKIQLEAK----IKEVTERAEDEEEINAELTAKKR---KLEDECSEL 954
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
+ D+ TL ++ K + +L ++ + +++L+K K +L + T
Sbjct: 955 KKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDL 1014
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQL-WRSKYESE 556
E + TL LE +D++ +E+E + DL+R K + +L S ++E
Sbjct: 1015 QMEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMDTE 1074
Query: 557 GVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
++L E +K + ++ + IE + L+K + L +E+L+ E++
Sbjct: 1075 N--DKQQLNEKLKKKEFEMSNLQGKIEDEQALAMQLQKKIKELQARIEELEEEIE 1127
Score = 55.2 bits (127), Expect = 3e-07
Identities = 47/237 (19%), Positives = 106/237 (44%), Gaps = 3/237 (1%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVK---QLQHQL 190
V ++ E++ L++ AK K + + E + + LD L E+ + K +L+ Q+
Sbjct: 979 VKNLTEEMAGLDETIAKLTKEK-KALQEAH--QQTLDDLQMEEDKVNTLTKAKTKLEQQV 1035
Query: 191 NEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTK 370
++++ ++ + DL+ AK+KL + + E+ QL++ ++ + +
Sbjct: 1036 DDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMDTENDKQQLNEKLKKKEFEMSNLQ 1095
Query: 371 RLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYE 550
++E L K + L+ ++ + E++E E +A ++Q S + E + + E
Sbjct: 1096 GKIEDEQALAMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLE 1155
Query: 551 SEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
G A S ++E K++ + ES Q +++ A V +L ++D
Sbjct: 1156 EAGGATSAQIELNKKREAEFQKMRRDLEESTLQHEATAAALRKKHADSVAELGKQID 1212
Score = 52.4 bits (120), Expect = 2e-06
Identities = 45/180 (25%), Positives = 87/180 (48%), Gaps = 4/180 (2%)
Frame = +2
Query: 29 MGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSN-EKAAQEKIVKQLQHQLNEVQS 205
M E+L + A E+ + V DL+ L +K +++L+ ++ E++S
Sbjct: 1769 MAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLGEAEQLALKGGKKQIQKLEARVRELES 1828
Query: 206 KADEANRTLNDLDAAK--KKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
+ + + ++++A K +K +L Q EE + +L + L T+++ KR A
Sbjct: 1829 EVESEQK--HNVEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQTKVKAYKRQA 1886
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADL-QRQLSKANAEAQLWRSKYESE 556
+E + L KFR L+H+L EEAE +AD+ + Q++K +++ +K SE
Sbjct: 1887 EEAEEQSNVNLAKFRKLQHEL--------EEAEERADIAESQVNKLRVKSREVHTKVISE 1938
Score = 47.2 bits (107), Expect = 7e-05
Identities = 46/227 (20%), Positives = 96/227 (42%), Gaps = 3/227 (1%)
Frame = +2
Query: 26 DMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNE-KAAQEKIVKQLQHQLNEVQ 202
D E++ L+ + + ++++ ++ ++ + E + A+EK K + +
Sbjct: 1712 DASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIVQEARNAEEKAKKAITDAAMMAE 1771
Query: 203 SKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVS-LTTQLEDTKRLA 379
E + + + L+ KK + DL +L EAE + K ++ L ++ + +
Sbjct: 1772 ELKKEQDTSAH-LERMKKNMEQTVKDLQLRLGEAEQLALKGGKKQIQKLEARVRELESEV 1830
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEG 559
+ E + + R E + + Q EE+ + LQ + K + + + K ++E
Sbjct: 1831 ESEQKHNVEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQTKVKAY--KRQAEE 1888
Query: 560 VARSEELEEAK-RKLQARLAEAEETIESLNQKVVALEKTKQRLATEV 697
+ AK RKLQ L EAEE + +V L + + T+V
Sbjct: 1889 AEEQSNVNLAKFRKLQHELEEAEERADIAESQVNKLRVKSREVHTKV 1935
Score = 40.7 bits (91), Expect = 0.006
Identities = 50/220 (22%), Positives = 98/220 (44%), Gaps = 15/220 (6%)
Frame = +2
Query: 104 VNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD--EANRTLND---LDAAKKK--L 262
++D G D L + A E+ +Q ++ E+++ + E R + + LDA+++ L
Sbjct: 1661 LDDAIRGQDDLKEQLAMVERRANLMQAEVEELRASLERTERGRKMAEQELLDASERVQLL 1720
Query: 263 SIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDL 442
+N+ L+ ++ E+ +SQ+ + + + + A + + A + + + E D
Sbjct: 1721 HTQNTSLINTKKKLETDISQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKK-EQDT 1779
Query: 443 DNIREQVEEEAEGKA-DLQRQLSKANAEAQLWRSKYESEGVARSEELE-----EAKRKLQ 604
E++++ E DLQ +L +A A K + AR ELE E K ++
Sbjct: 1780 SAHLERMKKNMEQTVKDLQLRLGEAEQLALKGGKKQIQKLEARVRELESEVESEQKHNVE 1839
Query: 605 A--RLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEV 718
A L + E ++ L + K RL V+ LQ +V
Sbjct: 1840 AVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQTKV 1879
>X15696-1|CAA33731.1| 1085|Homo sapiens protein ( Human muscle mRNA
for embryonic myosin heavy chain (SMHCE). ).
Length = 1085
Score = 229 bits (561), Expect = 7e-60
Identities = 112/235 (47%), Positives = 164/235 (69%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
V+++GEQ+D L ++K K EK ++++ E++DL + ++ +S KA EKI + L+ QL+E
Sbjct: 346 VAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEA 405
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
+ K +E R+L++L K +L E +L RQLEE ES VSQLS+ K + T Q E+ KR
Sbjct: 406 RGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQL 465
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEG 559
+EE + + L ++ HD D +REQ EEE EGKA+LQR LSKAN+E WR+KYE++
Sbjct: 466 EEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDA 525
Query: 560 VARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
+ R+EELEEAK+KL RL ++EE +E++N K +LEKTKQRL EVEDL ++V+R
Sbjct: 526 IQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVER 580
Score = 69.3 bits (162), Expect = 1e-11
Identities = 53/240 (22%), Positives = 115/240 (47%), Gaps = 4/240 (1%)
Frame = +2
Query: 14 RFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLN 193
R V M LD + + +A + + + ++N++ L H + + A K ++ +Q QL
Sbjct: 738 RTVETMQSALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLK 797
Query: 194 EVQSKADEANRTLNDLDAAKKKLSI--ENSDLLR-QLEEAESQVSQLSKIKVSLTTQLED 364
+ Q D+A R DL K++L+I ++LL+ ++EE + + Q + + +L D
Sbjct: 798 DTQLHLDDALRGQEDL---KEQLAIVERRANLLQAEVEELRATLEQTERARKLAEQELLD 854
Query: 365 TKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSK 544
+ + +L+ + LE DL ++ +VE+ + + + + KA +A + +
Sbjct: 855 SNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEE 914
Query: 545 YESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVV-ALEKTKQRLATEVEDLQLEVD 721
+ E S LE K+ L+ + + + ++ Q + +K Q+L T + +L+ E++
Sbjct: 915 LKKE-QDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLETRIRELEFELE 973
Score = 65.3 bits (152), Expect = 2e-10
Identities = 55/234 (23%), Positives = 112/234 (47%), Gaps = 2/234 (0%)
Frame = +2
Query: 26 DMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQS 205
++ QL++ NK K + + LR + KA ++ + + ++ + ++
Sbjct: 460 ELKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRT 519
Query: 206 KAD-EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLAD 382
K + +A + +L+ AKKKL+ D Q+E ++ + L K K L ++ED +
Sbjct: 520 KYETDAIQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVE 579
Query: 383 EEARERATLLGKFRNLEHDLDNIREQVEE-EAEGKADLQRQLSKANAEAQLWRSKYESEG 559
A L K RN + L + + EE +AE +A L+ S + +L ++ YE E
Sbjct: 580 RANSLAAALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKL-KNAYE-EA 637
Query: 560 VARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
+ + E ++ + L+ +A+ E I + + LEK+++++ E D+QL ++
Sbjct: 638 LDQLETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALE 691
Score = 63.7 bits (148), Expect = 7e-10
Identities = 56/231 (24%), Positives = 104/231 (45%), Gaps = 2/231 (0%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD 214
++++ LNK K+K E+ +V DL + L+ + E+ ++L+ L Q
Sbjct: 161 DKVNSLNKTKSKLEQ-------QVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESIL 213
Query: 215 EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEAR 394
+ LD KK E L ++E+ ++ Q K L ++E+ + + E
Sbjct: 214 DLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERA 273
Query: 395 ERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYE-SEGVARS 571
RA + + +L+ + E++EE A G Q +L+K EA+ + + + E +
Sbjct: 274 TRAKTEKQRSDYARELEELSERLEE-AGGVTSTQIELNKKR-EAEFLKLRRDLEEATLQH 331
Query: 572 EELEEAKRKLQA-RLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
E + RK A +AE E I++L + LEK K E++DL ++
Sbjct: 332 EAMVATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSME 382
Score = 62.1 bits (144), Expect = 2e-09
Identities = 44/186 (23%), Positives = 90/186 (48%), Gaps = 1/186 (0%)
Frame = +2
Query: 170 KQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLT 349
++ + +L + ++K E L L K L ++ L +AE + QL K K L
Sbjct: 3 QKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEERCDQLIKAKFQLE 62
Query: 350 TQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQ 529
++++ A++E A L K R LE + +++ +++ A ++++ K E +
Sbjct: 63 AKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKE--KHATENK 120
Query: 530 LWRSKYESEGVARS-EELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDL 706
+ E G+ + +L K+ LQ +A + +++ KV +L KTK +L +VEDL
Sbjct: 121 VKNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDL 180
Query: 707 QLEVDR 724
+ +++
Sbjct: 181 ESSLEQ 186
Score = 60.1 bits (139), Expect = 9e-09
Identities = 45/212 (21%), Positives = 104/212 (49%), Gaps = 10/212 (4%)
Frame = +2
Query: 74 EKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAK 253
E+ + + + D ++ ++ + A+ EK ++LQ ++ ++ + AN LD +
Sbjct: 533 EEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQ 592
Query: 254 KKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLE 433
+ ++ + EE+++++ K SL+T+L K +E + T+ + +NLE
Sbjct: 593 RNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVKRENKNLE 652
Query: 434 HDLDNIREQVEEEAEGKADLQR-----QLSKANAEAQLWRS----KYESEGVARSE-ELE 583
++ ++ EQ+ E + +L++ +L KA+ + L + ++E + R + EL
Sbjct: 653 QEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHEEAKILRIQLELT 712
Query: 584 EAKRKLQARLAEAEETIESLNQKVVALEKTKQ 679
+ K ++ ++AE +E IE L + +T Q
Sbjct: 713 QVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQ 744
Score = 54.0 bits (124), Expect = 6e-07
Identities = 48/215 (22%), Positives = 103/215 (47%), Gaps = 8/215 (3%)
Frame = +2
Query: 101 EVNDLRAGLDHLSNEKAAQ-EKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENS 277
E+ +++ +D EK + E++ + Q + +QS D R+ N+ KKK+ + +
Sbjct: 710 ELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKKKMEGDLN 769
Query: 278 DLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLAD------EEARERATLLGKFRN-LEH 436
++ QL A Q ++ K S+ QL+DT+ D E+ +E+ ++ + N L+
Sbjct: 770 EIEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQA 829
Query: 437 DLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLA 616
+++ +R +E+ + +++L +N QL ++ S + ++LE +LQ+ +
Sbjct: 830 EVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSL-IHTKKKLETDLMQLQSEVE 888
Query: 617 EAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
+A + +K +K A E+L+ E D
Sbjct: 889 DASRDARNAEEKA---KKAITDAAMMAEELKKEQD 920
Score = 52.4 bits (120), Expect = 2e-06
Identities = 54/263 (20%), Positives = 113/263 (42%), Gaps = 29/263 (11%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVK--------- 172
V D+ L+Q KL+ E+ + + ++ + + L N+K ++ +K
Sbjct: 177 VEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQL 236
Query: 173 ------------QLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQV 316
Q Q ++ E+Q++ +E + A + K + SD R+LEE ++
Sbjct: 237 QSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERL 296
Query: 317 SQ---LSKIKVSLTTQLE----DTKRLADEEARERATLLGKFRNLEHD-LDNIREQVEEE 472
+ ++ ++ L + E +R +E + ++ R D + + EQ++
Sbjct: 297 EEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVATLRKKHADSVAELGEQIDNL 356
Query: 473 AEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQK 652
K L+++ S+ E S ES +++ LE+ R L+ +L+EA E + +
Sbjct: 357 QRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKA-NLEKICRTLEDQLSEARGKNEEIQRS 415
Query: 653 VVALEKTKQRLATEVEDLQLEVD 721
+ L K RL TE +L +++
Sbjct: 416 LSELTTQKSRLQTEAGELSRQLE 438
Score = 48.0 bits (109), Expect = 4e-05
Identities = 40/169 (23%), Positives = 76/169 (44%), Gaps = 2/169 (1%)
Frame = +2
Query: 29 MGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSN-EKAAQEKIVKQLQHQLNEVQS 205
M E+L + A E+ + V DL+ LD +K +++L+ ++ E++
Sbjct: 911 MAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLETRIRELEF 970
Query: 206 KADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADE 385
+ + + + +K +L Q EE V +L + L +++ KR A+E
Sbjct: 971 ELEGEQKKNTESVKGLRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKVKSYKRQAEE 1030
Query: 386 EARERATLLGKFRNLEHDLDNIREQVEEEAEGKADL-QRQLSKANAEAQ 529
+ L KFR +H+L EEAE +AD+ + Q++K A+ +
Sbjct: 1031 ADEQANAHLTKFRKAQHEL--------EEAEERADIAESQVNKLRAKTR 1071
Score = 41.1 bits (92), Expect = 0.004
Identities = 63/267 (23%), Positives = 112/267 (41%), Gaps = 28/267 (10%)
Frame = +2
Query: 2 NSAGRFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLD----HLSNEKAAQEKIV 169
N A R M L+++ + A + A+ + ++ L HL + QE +
Sbjct: 755 NEAIRLKKKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLK 814
Query: 170 KQL---QHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKV 340
+QL + + N +Q++ +E TL + A+K E D +++ +Q + L K
Sbjct: 815 EQLAIVERRANLLQAEVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSLIHTKK 874
Query: 341 SLTTQL-------EDTKR---LADEEARERAT---LLGKFRNLEHDLDNIREQVEEEAEG 481
L T L ED R A+E+A++ T ++ + E D E++++ E
Sbjct: 875 KLETDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQ 934
Query: 482 KA-DLQRQLSKANAEAQLWRSKYESEGVARSEELE-----EAKRKLQA--RLAEAEETIE 637
DLQ +L +A A K + R ELE E K+ ++ L + E ++
Sbjct: 935 TVKDLQHRLDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRKYERRVK 994
Query: 638 SLNQKVVALEKTKQRLATEVEDLQLEV 718
L + K RL V+ LQ++V
Sbjct: 995 ELTYQSEEDRKNVLRLQDLVDKLQVKV 1021
>AY517555-1|AAT44528.1| 941|Homo sapiens hypothetical
rhabdomyosarcoma antigen MU-RMS-40.3 protein.
Length = 941
Score = 229 bits (561), Expect = 7e-60
Identities = 112/235 (47%), Positives = 164/235 (69%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
V+++GEQ+D L ++K K EK ++++ E++DL + ++ +S KA EKI + L+ QL+E
Sbjct: 202 VAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEA 261
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
+ K +E R+L++L K +L E +L RQLEE ES VSQLS+ K + T Q E+ KR
Sbjct: 262 RGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQL 321
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEG 559
+EE + + L ++ HD D +REQ EEE EGKA+LQR LSKAN+E WR+KYE++
Sbjct: 322 EEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDA 381
Query: 560 VARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
+ R+EELEEAK+KL RL ++EE +E++N K +LEKTKQRL EVEDL ++V+R
Sbjct: 382 IQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVER 436
Score = 69.3 bits (162), Expect = 1e-11
Identities = 53/240 (22%), Positives = 115/240 (47%), Gaps = 4/240 (1%)
Frame = +2
Query: 14 RFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLN 193
R V M LD + + +A + + + ++N++ L H + + A K ++ +Q QL
Sbjct: 594 RTVETMQSALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLK 653
Query: 194 EVQSKADEANRTLNDLDAAKKKLSI--ENSDLLR-QLEEAESQVSQLSKIKVSLTTQLED 364
+ Q D+A R DL K++L+I ++LL+ ++EE + + Q + + +L D
Sbjct: 654 DTQLHLDDALRGQEDL---KEQLAIVERRANLLQAEVEELRATLEQTERARKLAEQELLD 710
Query: 365 TKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSK 544
+ + +L+ + LE DL ++ +VE+ + + + + KA +A + +
Sbjct: 711 SNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEE 770
Query: 545 YESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVV-ALEKTKQRLATEVEDLQLEVD 721
+ E S LE K+ L+ + + + ++ Q + +K Q+L T + +L+ E++
Sbjct: 771 LKKE-QDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLETRIRELEFELE 829
Score = 65.3 bits (152), Expect = 2e-10
Identities = 55/234 (23%), Positives = 112/234 (47%), Gaps = 2/234 (0%)
Frame = +2
Query: 26 DMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQS 205
++ QL++ NK K + + LR + KA ++ + + ++ + ++
Sbjct: 316 ELKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRT 375
Query: 206 KAD-EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLAD 382
K + +A + +L+ AKKKL+ D Q+E ++ + L K K L ++ED +
Sbjct: 376 KYETDAIQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVE 435
Query: 383 EEARERATLLGKFRNLEHDLDNIREQVEE-EAEGKADLQRQLSKANAEAQLWRSKYESEG 559
A L K RN + L + + EE +AE +A L+ S + +L ++ YE E
Sbjct: 436 RANSLAAALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKL-KNAYE-EA 493
Query: 560 VARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
+ + E ++ + L+ +A+ E I + + LEK+++++ E D+QL ++
Sbjct: 494 LDQLETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALE 547
Score = 63.7 bits (148), Expect = 7e-10
Identities = 56/231 (24%), Positives = 104/231 (45%), Gaps = 2/231 (0%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD 214
++++ LNK K+K E+ +V DL + L+ + E+ ++L+ L Q
Sbjct: 17 DKVNSLNKTKSKLEQ-------QVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESIL 69
Query: 215 EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEAR 394
+ LD KK E L ++E+ ++ Q K L ++E+ + + E
Sbjct: 70 DLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERA 129
Query: 395 ERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYE-SEGVARS 571
RA + + +L+ + E++EE A G Q +L+K EA+ + + + E +
Sbjct: 130 TRAKTEKQRSDYARELEELSERLEE-AGGVTSTQIELNKKR-EAEFLKLRRDLEEATLQH 187
Query: 572 EELEEAKRKLQA-RLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
E + RK A +AE E I++L + LEK K E++DL ++
Sbjct: 188 EAMVATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSME 238
Score = 60.1 bits (139), Expect = 9e-09
Identities = 45/212 (21%), Positives = 104/212 (49%), Gaps = 10/212 (4%)
Frame = +2
Query: 74 EKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAK 253
E+ + + + D ++ ++ + A+ EK ++LQ ++ ++ + AN LD +
Sbjct: 389 EEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQ 448
Query: 254 KKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLE 433
+ ++ + EE+++++ K SL+T+L K +E + T+ + +NLE
Sbjct: 449 RNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVKRENKNLE 508
Query: 434 HDLDNIREQVEEEAEGKADLQR-----QLSKANAEAQLWRS----KYESEGVARSE-ELE 583
++ ++ EQ+ E + +L++ +L KA+ + L + ++E + R + EL
Sbjct: 509 QEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHEEAKILRIQLELT 568
Query: 584 EAKRKLQARLAEAEETIESLNQKVVALEKTKQ 679
+ K ++ ++AE +E IE L + +T Q
Sbjct: 569 QVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQ 600
Score = 54.0 bits (124), Expect = 6e-07
Identities = 48/215 (22%), Positives = 103/215 (47%), Gaps = 8/215 (3%)
Frame = +2
Query: 101 EVNDLRAGLDHLSNEKAAQ-EKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENS 277
E+ +++ +D EK + E++ + Q + +QS D R+ N+ KKK+ + +
Sbjct: 566 ELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKKKMEGDLN 625
Query: 278 DLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLAD------EEARERATLLGKFRN-LEH 436
++ QL A Q ++ K S+ QL+DT+ D E+ +E+ ++ + N L+
Sbjct: 626 EIEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQA 685
Query: 437 DLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLA 616
+++ +R +E+ + +++L +N QL ++ S + ++LE +LQ+ +
Sbjct: 686 EVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSL-IHTKKKLETDLMQLQSEVE 744
Query: 617 EAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
+A + +K +K A E+L+ E D
Sbjct: 745 DASRDARNAEEKA---KKAITDAAMMAEELKKEQD 776
Score = 52.4 bits (120), Expect = 2e-06
Identities = 54/263 (20%), Positives = 113/263 (42%), Gaps = 29/263 (11%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVK--------- 172
V D+ L+Q KL+ E+ + + ++ + + L N+K ++ +K
Sbjct: 33 VEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQL 92
Query: 173 ------------QLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQV 316
Q Q ++ E+Q++ +E + A + K + SD R+LEE ++
Sbjct: 93 QSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERL 152
Query: 317 SQ---LSKIKVSLTTQLE----DTKRLADEEARERATLLGKFRNLEHD-LDNIREQVEEE 472
+ ++ ++ L + E +R +E + ++ R D + + EQ++
Sbjct: 153 EEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVATLRKKHADSVAELGEQIDNL 212
Query: 473 AEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQK 652
K L+++ S+ E S ES +++ LE+ R L+ +L+EA E + +
Sbjct: 213 QRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKA-NLEKICRTLEDQLSEARGKNEEIQRS 271
Query: 653 VVALEKTKQRLATEVEDLQLEVD 721
+ L K RL TE +L +++
Sbjct: 272 LSELTTQKSRLQTEAGELSRQLE 294
Score = 48.0 bits (109), Expect = 4e-05
Identities = 40/169 (23%), Positives = 76/169 (44%), Gaps = 2/169 (1%)
Frame = +2
Query: 29 MGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSN-EKAAQEKIVKQLQHQLNEVQS 205
M E+L + A E+ + V DL+ LD +K +++L+ ++ E++
Sbjct: 767 MAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLETRIRELEF 826
Query: 206 KADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADE 385
+ + + + +K +L Q EE V +L + L +++ KR A+E
Sbjct: 827 ELEGEQKKNTESVKGLRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKVKSYKRQAEE 886
Query: 386 EARERATLLGKFRNLEHDLDNIREQVEEEAEGKADL-QRQLSKANAEAQ 529
+ L KFR +H+L EEAE +AD+ + Q++K A+ +
Sbjct: 887 ADEQANAHLTKFRKAQHEL--------EEAEERADIAESQVNKLRAKTR 927
Score = 41.1 bits (92), Expect = 0.004
Identities = 63/267 (23%), Positives = 112/267 (41%), Gaps = 28/267 (10%)
Frame = +2
Query: 2 NSAGRFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLD----HLSNEKAAQEKIV 169
N A R M L+++ + A + A+ + ++ L HL + QE +
Sbjct: 611 NEAIRLKKKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLK 670
Query: 170 KQL---QHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKV 340
+QL + + N +Q++ +E TL + A+K E D +++ +Q + L K
Sbjct: 671 EQLAIVERRANLLQAEVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSLIHTKK 730
Query: 341 SLTTQL-------EDTKR---LADEEARERAT---LLGKFRNLEHDLDNIREQVEEEAEG 481
L T L ED R A+E+A++ T ++ + E D E++++ E
Sbjct: 731 KLETDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQ 790
Query: 482 KA-DLQRQLSKANAEAQLWRSKYESEGVARSEELE-----EAKRKLQA--RLAEAEETIE 637
DLQ +L +A A K + R ELE E K+ ++ L + E ++
Sbjct: 791 TVKDLQHRLDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRKYERRVK 850
Query: 638 SLNQKVVALEKTKQRLATEVEDLQLEV 718
L + K RL V+ LQ++V
Sbjct: 851 ELTYQSEEDRKNVLRLQDLVDKLQVKV 877
>X51593-1|CAA35942.1| 1085|Homo sapiens embryonic myosin heavy chain
(1085 AA) protein.
Length = 1085
Score = 228 bits (558), Expect = 2e-59
Identities = 112/235 (47%), Positives = 164/235 (69%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
V+++GEQ+D L ++K K EK ++++ E++DL + ++ +S KA EKI + L+ QL+E
Sbjct: 346 VAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEA 405
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
+ K +E R+L++L K +L E +L RQLEE ES VSQLS+ K + T Q E+ KR
Sbjct: 406 RGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQL 465
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEG 559
+EE + + L ++ HD D +REQ EEE EGKA+LQR LSKAN+E WR+KYE++
Sbjct: 466 EEENKAKNALGHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDA 525
Query: 560 VARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
+ R+EELEEAK+KL RL ++EE +E++N K +LEKTKQRL EVEDL ++V+R
Sbjct: 526 IQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVER 580
Score = 68.1 bits (159), Expect = 3e-11
Identities = 53/240 (22%), Positives = 114/240 (47%), Gaps = 4/240 (1%)
Frame = +2
Query: 14 RFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLN 193
R V M LD + +A + + + ++N++ L H + + A K ++ +Q QL
Sbjct: 738 RTVETMQSALDAEVRRANEAIRLKKKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLK 797
Query: 194 EVQSKADEANRTLNDLDAAKKKLSI--ENSDLLR-QLEEAESQVSQLSKIKVSLTTQLED 364
+ Q D+A R DL K++L+I ++LL+ ++EE + + Q + + +L D
Sbjct: 798 DTQLHLDDALRGQEDL---KEQLAIVERRANLLQAEVEELRATLEQTERARKLAEQELLD 854
Query: 365 TKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSK 544
+ + +L+ + LE DL ++ +VE+ + + + + KA +A + +
Sbjct: 855 SNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEE 914
Query: 545 YESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVV-ALEKTKQRLATEVEDLQLEVD 721
+ E S LE K+ L+ + + + ++ Q + +K Q+L T + +L+ E++
Sbjct: 915 LKKE-QDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLETRIRELEFELE 973
Score = 64.9 bits (151), Expect = 3e-10
Identities = 55/234 (23%), Positives = 112/234 (47%), Gaps = 2/234 (0%)
Frame = +2
Query: 26 DMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQS 205
++ QL++ NK K + + LR + KA ++ + + ++ + ++
Sbjct: 460 ELKRQLEEENKAKNALGHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRT 519
Query: 206 KAD-EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLAD 382
K + +A + +L+ AKKKL+ D Q+E ++ + L K K L ++ED +
Sbjct: 520 KYETDAIQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVE 579
Query: 383 EEARERATLLGKFRNLEHDLDNIREQVEE-EAEGKADLQRQLSKANAEAQLWRSKYESEG 559
A L K RN + L + + EE +AE +A L+ S + +L ++ YE E
Sbjct: 580 RANSLAAALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKL-KNAYE-EA 637
Query: 560 VARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
+ + E ++ + L+ +A+ E I + + LEK+++++ E D+QL ++
Sbjct: 638 LDQLETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALE 691
Score = 63.7 bits (148), Expect = 7e-10
Identities = 56/231 (24%), Positives = 104/231 (45%), Gaps = 2/231 (0%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD 214
++++ LNK K+K E+ +V DL + L+ + E+ ++L+ L Q
Sbjct: 161 DKVNSLNKTKSKLEQ-------QVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESIL 213
Query: 215 EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEAR 394
+ LD KK E L ++E+ ++ Q K L ++E+ + + E
Sbjct: 214 DLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERA 273
Query: 395 ERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYE-SEGVARS 571
RA + + +L+ + E++EE A G Q +L+K EA+ + + + E +
Sbjct: 274 TRAKTEKQRSDYARELEELSERLEE-AGGVTSTQIELNKKR-EAEFLKLRRDLEEATLQH 331
Query: 572 EELEEAKRKLQA-RLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
E + RK A +AE E I++L + LEK K E++DL ++
Sbjct: 332 EAMVATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSME 382
Score = 62.1 bits (144), Expect = 2e-09
Identities = 44/186 (23%), Positives = 90/186 (48%), Gaps = 1/186 (0%)
Frame = +2
Query: 170 KQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLT 349
++ + +L + ++K E L L K L ++ L +AE + QL K K L
Sbjct: 3 QKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEERCDQLIKAKFQLE 62
Query: 350 TQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQ 529
++++ A++E A L K R LE + +++ +++ A ++++ K E +
Sbjct: 63 AKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKE--KHATENK 120
Query: 530 LWRSKYESEGVARS-EELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDL 706
+ E G+ + +L K+ LQ +A + +++ KV +L KTK +L +VEDL
Sbjct: 121 VKNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDL 180
Query: 707 QLEVDR 724
+ +++
Sbjct: 181 ESSLEQ 186
Score = 60.1 bits (139), Expect = 9e-09
Identities = 45/212 (21%), Positives = 104/212 (49%), Gaps = 10/212 (4%)
Frame = +2
Query: 74 EKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAK 253
E+ + + + D ++ ++ + A+ EK ++LQ ++ ++ + AN LD +
Sbjct: 533 EEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQ 592
Query: 254 KKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLE 433
+ ++ + EE+++++ K SL+T+L K +E + T+ + +NLE
Sbjct: 593 RNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVKRENKNLE 652
Query: 434 HDLDNIREQVEEEAEGKADLQR-----QLSKANAEAQLWRS----KYESEGVARSE-ELE 583
++ ++ EQ+ E + +L++ +L KA+ + L + ++E + R + EL
Sbjct: 653 QEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHEEAKILRIQLELT 712
Query: 584 EAKRKLQARLAEAEETIESLNQKVVALEKTKQ 679
+ K ++ ++AE +E IE L + +T Q
Sbjct: 713 QVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQ 744
Score = 53.6 bits (123), Expect = 8e-07
Identities = 48/215 (22%), Positives = 102/215 (47%), Gaps = 8/215 (3%)
Frame = +2
Query: 101 EVNDLRAGLDHLSNEKAAQ-EKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENS 277
E+ +++ +D EK + E++ + Q + +QS D R N+ KKK+ + +
Sbjct: 710 ELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRRANEAIRLKKKMEGDLN 769
Query: 278 DLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLAD------EEARERATLLGKFRN-LEH 436
++ QL A Q ++ K S+ QL+DT+ D E+ +E+ ++ + N L+
Sbjct: 770 EIEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQA 829
Query: 437 DLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLA 616
+++ +R +E+ + +++L +N QL ++ S + ++LE +LQ+ +
Sbjct: 830 EVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSL-IHTKKKLETDLMQLQSEVE 888
Query: 617 EAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
+A + +K +K A E+L+ E D
Sbjct: 889 DASRDARNAEEKA---KKAITDAAMMAEELKKEQD 920
Score = 52.4 bits (120), Expect = 2e-06
Identities = 54/263 (20%), Positives = 113/263 (42%), Gaps = 29/263 (11%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVK--------- 172
V D+ L+Q KL+ E+ + + ++ + + L N+K ++ +K
Sbjct: 177 VEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQL 236
Query: 173 ------------QLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQV 316
Q Q ++ E+Q++ +E + A + K + SD R+LEE ++
Sbjct: 237 QSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERL 296
Query: 317 SQ---LSKIKVSLTTQLE----DTKRLADEEARERATLLGKFRNLEHD-LDNIREQVEEE 472
+ ++ ++ L + E +R +E + ++ R D + + EQ++
Sbjct: 297 EEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVATLRKKHADSVAELGEQIDNL 356
Query: 473 AEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQK 652
K L+++ S+ E S ES +++ LE+ R L+ +L+EA E + +
Sbjct: 357 QRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKA-NLEKICRTLEDQLSEARGKNEEIQRS 415
Query: 653 VVALEKTKQRLATEVEDLQLEVD 721
+ L K RL TE +L +++
Sbjct: 416 LSELTTQKSRLQTEAGELSRQLE 438
Score = 48.0 bits (109), Expect = 4e-05
Identities = 40/169 (23%), Positives = 76/169 (44%), Gaps = 2/169 (1%)
Frame = +2
Query: 29 MGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSN-EKAAQEKIVKQLQHQLNEVQS 205
M E+L + A E+ + V DL+ LD +K +++L+ ++ E++
Sbjct: 911 MAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLETRIRELEF 970
Query: 206 KADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADE 385
+ + + + +K +L Q EE V +L + L +++ KR A+E
Sbjct: 971 ELEGEQKKNTESVKGLRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKVKSYKRQAEE 1030
Query: 386 EARERATLLGKFRNLEHDLDNIREQVEEEAEGKADL-QRQLSKANAEAQ 529
+ L KFR +H+L EEAE +AD+ + Q++K A+ +
Sbjct: 1031 ADEQANAHLTKFRKAQHEL--------EEAEERADIAESQVNKLRAKTR 1071
Score = 41.1 bits (92), Expect = 0.004
Identities = 63/267 (23%), Positives = 112/267 (41%), Gaps = 28/267 (10%)
Frame = +2
Query: 2 NSAGRFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLD----HLSNEKAAQEKIV 169
N A R M L+++ + A + A+ + ++ L HL + QE +
Sbjct: 755 NEAIRLKKKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLK 814
Query: 170 KQL---QHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKV 340
+QL + + N +Q++ +E TL + A+K E D +++ +Q + L K
Sbjct: 815 EQLAIVERRANLLQAEVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSLIHTKK 874
Query: 341 SLTTQL-------EDTKR---LADEEARERAT---LLGKFRNLEHDLDNIREQVEEEAEG 481
L T L ED R A+E+A++ T ++ + E D E++++ E
Sbjct: 875 KLETDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQ 934
Query: 482 KA-DLQRQLSKANAEAQLWRSKYESEGVARSEELE-----EAKRKLQA--RLAEAEETIE 637
DLQ +L +A A K + R ELE E K+ ++ L + E ++
Sbjct: 935 TVKDLQHRLDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRKYERRVK 994
Query: 638 SLNQKVVALEKTKQRLATEVEDLQLEV 718
L + K RL V+ LQ++V
Sbjct: 995 ELTYQSEEDRKNVLRLQDLVDKLQVKV 1021
>X13988-1|CAA32167.1| 1940|Homo sapiens protein ( Human mRNA for
embryonic myosin heavy chain. ).
Length = 1940
Score = 227 bits (555), Expect = 3e-59
Identities = 111/235 (47%), Positives = 163/235 (69%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
V+++GEQ+D L ++K K EK ++++ E++DL + ++ +S KA EKI + L+ QL+E
Sbjct: 1201 VAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEA 1260
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
+ K +E R+L++L K +L E +L RQLEE ES VSQLS+ K + T Q E+ KR
Sbjct: 1261 RGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQL 1320
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEG 559
+EE + + L ++ HD D +REQ EEE EGKA+LQR LSKAN+E WR+KYE++
Sbjct: 1321 EEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDA 1380
Query: 560 VARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
+ R+EELEEA+ KL RL ++EE +E++N K +LEKTKQRL EVEDL ++V+R
Sbjct: 1381 IQRTEELEEAQEKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVER 1435
Score = 69.3 bits (162), Expect = 1e-11
Identities = 53/240 (22%), Positives = 115/240 (47%), Gaps = 4/240 (1%)
Frame = +2
Query: 14 RFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLN 193
R V M LD + + +A + + + ++N++ L H + + A K ++ +Q QL
Sbjct: 1593 RTVETMQSALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLK 1652
Query: 194 EVQSKADEANRTLNDLDAAKKKLSI--ENSDLLR-QLEEAESQVSQLSKIKVSLTTQLED 364
+ Q D+A R DL K++L+I ++LL+ ++EE + + Q + + +L D
Sbjct: 1653 DTQLHLDDALRGQEDL---KEQLAIVERRANLLQAEVEELRATLEQTERARKLAEQELLD 1709
Query: 365 TKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSK 544
+ + +L+ + LE DL ++ +VE+ + + + + KA +A + +
Sbjct: 1710 SNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEE 1769
Query: 545 YESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVV-ALEKTKQRLATEVEDLQLEVD 721
+ E S LE K+ L+ + + + ++ Q + +K Q+L T + +L+ E++
Sbjct: 1770 LKKE-QDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLETRIRELEFELE 1828
Score = 64.5 bits (150), Expect = 4e-10
Identities = 46/195 (23%), Positives = 94/195 (48%), Gaps = 1/195 (0%)
Frame = +2
Query: 143 EKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQ 322
E A ++ ++ + +L + ++K E L L K L ++ L +AE + Q
Sbjct: 849 EMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEERCDQ 908
Query: 323 LSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQ 502
L K K L ++++ A++E A L K R LE + +++ +++ A ++++
Sbjct: 909 LIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKE 968
Query: 503 LSKANAEAQLWRSKYESEGVARS-EELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQ 679
K E ++ E G+ + +L K+ LQ +A + +++ KV +L KTK
Sbjct: 969 --KHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSLNKTKS 1026
Query: 680 RLATEVEDLQLEVDR 724
+L +VEDL+ +++
Sbjct: 1027 KLEQQVEDLESSLEQ 1041
Score = 63.7 bits (148), Expect = 7e-10
Identities = 56/231 (24%), Positives = 104/231 (45%), Gaps = 2/231 (0%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD 214
++++ LNK K+K E+ +V DL + L+ + E+ ++L+ L Q
Sbjct: 1016 DKVNSLNKTKSKLEQ-------QVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESIL 1068
Query: 215 EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEAR 394
+ LD KK E L ++E+ ++ Q K L ++E+ + + E
Sbjct: 1069 DLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERA 1128
Query: 395 ERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYE-SEGVARS 571
RA + + +L+ + E++EE A G Q +L+K EA+ + + + E +
Sbjct: 1129 TRAKTEKQRSDYARELEELSERLEE-AGGVTSTQIELNKKR-EAEFLKLRRDLEEATLQH 1186
Query: 572 EELEEAKRKLQA-RLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
E + RK A +AE E I++L + LEK K E++DL ++
Sbjct: 1187 EAMVATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSME 1237
Score = 62.1 bits (144), Expect = 2e-09
Identities = 53/234 (22%), Positives = 112/234 (47%), Gaps = 2/234 (0%)
Frame = +2
Query: 26 DMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQS 205
++ QL++ NK K + + LR + KA ++ + + ++ + ++
Sbjct: 1315 ELKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRT 1374
Query: 206 KAD-EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLAD 382
K + +A + +L+ A++KL+ D Q+E ++ + L K K L ++ED +
Sbjct: 1375 KYETDAIQRTEELEEAQEKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVE 1434
Query: 383 EEARERATLLGKFRNLEHDLDNIREQVEE-EAEGKADLQRQLSKANAEAQLWRSKYESEG 559
A L K RN + L + + EE +AE +A L+ S + +L ++ YE E
Sbjct: 1435 RANSLAAALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKL-KNAYE-EA 1492
Query: 560 VARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
+ + E ++ + L+ +A+ E I + + LEK+++++ E D+QL ++
Sbjct: 1493 LDQLETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALE 1546
Score = 59.7 bits (138), Expect = 1e-08
Identities = 45/212 (21%), Positives = 104/212 (49%), Gaps = 10/212 (4%)
Frame = +2
Query: 74 EKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAK 253
E+ + + + D ++ ++ + A+ EK ++LQ ++ ++ + AN LD +
Sbjct: 1388 EEAQEKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQ 1447
Query: 254 KKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLE 433
+ ++ + EE+++++ K SL+T+L K +E + T+ + +NLE
Sbjct: 1448 RNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVKRENKNLE 1507
Query: 434 HDLDNIREQVEEEAEGKADLQR-----QLSKANAEAQLWRS----KYESEGVARSE-ELE 583
++ ++ EQ+ E + +L++ +L KA+ + L + ++E + R + EL
Sbjct: 1508 QEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHEEAKILRIQLELT 1567
Query: 584 EAKRKLQARLAEAEETIESLNQKVVALEKTKQ 679
+ K ++ ++AE +E IE L + +T Q
Sbjct: 1568 QVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQ 1599
Score = 54.0 bits (124), Expect = 6e-07
Identities = 48/215 (22%), Positives = 103/215 (47%), Gaps = 8/215 (3%)
Frame = +2
Query: 101 EVNDLRAGLDHLSNEKAAQ-EKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENS 277
E+ +++ +D EK + E++ + Q + +QS D R+ N+ KKK+ + +
Sbjct: 1565 ELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKKKMEGDLN 1624
Query: 278 DLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLAD------EEARERATLLGKFRN-LEH 436
++ QL A Q ++ K S+ QL+DT+ D E+ +E+ ++ + N L+
Sbjct: 1625 EIEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQA 1684
Query: 437 DLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLA 616
+++ +R +E+ + +++L +N QL ++ S + ++LE +LQ+ +
Sbjct: 1685 EVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSL-IHTKKKLETDLMQLQSEVE 1743
Query: 617 EAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
+A + +K +K A E+L+ E D
Sbjct: 1744 DASRDARNAEEKA---KKAITDAAMMAEELKKEQD 1775
Score = 52.4 bits (120), Expect = 2e-06
Identities = 54/263 (20%), Positives = 113/263 (42%), Gaps = 29/263 (11%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVK--------- 172
V D+ L+Q KL+ E+ + + ++ + + L N+K ++ +K
Sbjct: 1032 VEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQL 1091
Query: 173 ------------QLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQV 316
Q Q ++ E+Q++ +E + A + K + SD R+LEE ++
Sbjct: 1092 QSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERL 1151
Query: 317 SQ---LSKIKVSLTTQLE----DTKRLADEEARERATLLGKFRNLEHD-LDNIREQVEEE 472
+ ++ ++ L + E +R +E + ++ R D + + EQ++
Sbjct: 1152 EEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVATLRKKHADSVAELGEQIDNL 1211
Query: 473 AEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQK 652
K L+++ S+ E S ES +++ LE+ R L+ +L+EA E + +
Sbjct: 1212 QRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKA-NLEKICRTLEDQLSEARGKNEEIQRS 1270
Query: 653 VVALEKTKQRLATEVEDLQLEVD 721
+ L K RL TE +L +++
Sbjct: 1271 LSELTTQKSRLQTEAGELSRQLE 1293
Score = 48.0 bits (109), Expect = 4e-05
Identities = 40/169 (23%), Positives = 76/169 (44%), Gaps = 2/169 (1%)
Frame = +2
Query: 29 MGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSN-EKAAQEKIVKQLQHQLNEVQS 205
M E+L + A E+ + V DL+ LD +K +++L+ ++ E++
Sbjct: 1766 MAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLETRIRELEF 1825
Query: 206 KADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADE 385
+ + + + +K +L Q EE V +L + L +++ KR A+E
Sbjct: 1826 ELEGEQKKNTESVKGLRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKVKSYKRQAEE 1885
Query: 386 EARERATLLGKFRNLEHDLDNIREQVEEEAEGKADL-QRQLSKANAEAQ 529
+ L KFR +H+L EEAE +AD+ + Q++K A+ +
Sbjct: 1886 ADEQANAHLTKFRKAQHEL--------EEAEERADIAESQVNKLRAKTR 1926
Score = 41.1 bits (92), Expect = 0.004
Identities = 63/267 (23%), Positives = 112/267 (41%), Gaps = 28/267 (10%)
Frame = +2
Query: 2 NSAGRFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLD----HLSNEKAAQEKIV 169
N A R M L+++ + A + A+ + ++ L HL + QE +
Sbjct: 1610 NEAIRLKKKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLK 1669
Query: 170 KQL---QHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKV 340
+QL + + N +Q++ +E TL + A+K E D +++ +Q + L K
Sbjct: 1670 EQLAIVERRANLLQAEVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSLIHTKK 1729
Query: 341 SLTTQL-------EDTKR---LADEEARERAT---LLGKFRNLEHDLDNIREQVEEEAEG 481
L T L ED R A+E+A++ T ++ + E D E++++ E
Sbjct: 1730 KLETDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQ 1789
Query: 482 KA-DLQRQLSKANAEAQLWRSKYESEGVARSEELE-----EAKRKLQA--RLAEAEETIE 637
DLQ +L +A A K + R ELE E K+ ++ L + E ++
Sbjct: 1790 TVKDLQHRLDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRKYERRVK 1849
Query: 638 SLNQKVVALEKTKQRLATEVEDLQLEV 718
L + K RL V+ LQ++V
Sbjct: 1850 ELTYQSEEDRKNVLRLQDLVDKLQVKV 1876
>X13100-1|CAA31492.1| 1167|Homo sapiens myosin heavy chain (1167 AA)
protein.
Length = 1167
Score = 227 bits (555), Expect = 3e-59
Identities = 111/235 (47%), Positives = 163/235 (69%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
V+++GEQ+D L ++K K EK ++++ E++DL + ++ +S KA EKI + L+ QL+E
Sbjct: 428 VAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEA 487
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
+ K +E R+L++L K +L E +L RQLEE ES VSQLS+ K + T Q E+ KR
Sbjct: 488 RGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQL 547
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEG 559
+EE + + L ++ HD D +REQ EEE EGKA+LQR LSKAN+E WR+KYE++
Sbjct: 548 EEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDA 607
Query: 560 VARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
+ R+EELEEA+ KL RL ++EE +E++N K +LEKTKQRL EVEDL ++V+R
Sbjct: 608 IQRTEELEEAQEKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVER 662
Score = 70.5 bits (165), Expect = 6e-12
Identities = 53/240 (22%), Positives = 116/240 (48%), Gaps = 4/240 (1%)
Frame = +2
Query: 14 RFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLN 193
R V M LD + + +A + + + ++N++ L H + + A K ++ +Q QL
Sbjct: 820 RTVETMQSALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLK 879
Query: 194 EVQSKADEANRTLNDLDAAKKKLSI--ENSDLLR-QLEEAESQVSQLSKIKVSLTTQLED 364
+ Q D+A +T DL K++L+I ++LL+ ++EE + + Q + + +L D
Sbjct: 880 DTQLHLDDALQTQEDL---KEQLAIVERRANLLQAEVEELRATLEQTERARKLAEQELLD 936
Query: 365 TKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSK 544
+ + +L+ + LE DL ++ +VE+ + + + + KA +A + +
Sbjct: 937 SNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEE 996
Query: 545 YESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVV-ALEKTKQRLATEVEDLQLEVD 721
+ E S LE K+ L+ + + + ++ Q + +K Q+L T + +L+ E++
Sbjct: 997 LKKE-QDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLETRIRELEFELE 1055
Score = 64.5 bits (150), Expect = 4e-10
Identities = 46/195 (23%), Positives = 94/195 (48%), Gaps = 1/195 (0%)
Frame = +2
Query: 143 EKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQ 322
E A ++ ++ + +L + ++K E L L K L ++ L +AE + Q
Sbjct: 76 EMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEERCDQ 135
Query: 323 LSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQ 502
L K K L ++++ A++E A L K R LE + +++ +++ A ++++
Sbjct: 136 LIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKE 195
Query: 503 LSKANAEAQLWRSKYESEGVARS-EELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQ 679
K E ++ E G+ + +L K+ LQ +A + +++ KV +L KTK
Sbjct: 196 --KHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSLNKTKS 253
Query: 680 RLATEVEDLQLEVDR 724
+L +VEDL+ +++
Sbjct: 254 KLEQQVEDLESSLEQ 268
Score = 63.7 bits (148), Expect = 7e-10
Identities = 56/231 (24%), Positives = 104/231 (45%), Gaps = 2/231 (0%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD 214
++++ LNK K+K E+ +V DL + L+ + E+ ++L+ L Q
Sbjct: 243 DKVNSLNKTKSKLEQ-------QVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESIL 295
Query: 215 EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEAR 394
+ LD KK E L ++E+ ++ Q K L ++E+ + + E
Sbjct: 296 DLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERA 355
Query: 395 ERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYE-SEGVARS 571
RA + + +L+ + E++EE A G Q +L+K EA+ + + + E +
Sbjct: 356 TRAKTEKQRSDYARELEELSERLEE-AGGVTSTQIELNKKR-EAEFLKLRRDLEEATLQH 413
Query: 572 EELEEAKRKLQA-RLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
E + RK A +AE E I++L + LEK K E++DL ++
Sbjct: 414 EAMVATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSME 464
Score = 62.1 bits (144), Expect = 2e-09
Identities = 53/234 (22%), Positives = 112/234 (47%), Gaps = 2/234 (0%)
Frame = +2
Query: 26 DMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQS 205
++ QL++ NK K + + LR + KA ++ + + ++ + ++
Sbjct: 542 ELKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRT 601
Query: 206 KAD-EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLAD 382
K + +A + +L+ A++KL+ D Q+E ++ + L K K L ++ED +
Sbjct: 602 KYETDAIQRTEELEEAQEKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVE 661
Query: 383 EEARERATLLGKFRNLEHDLDNIREQVEE-EAEGKADLQRQLSKANAEAQLWRSKYESEG 559
A L K RN + L + + EE +AE +A L+ S + +L ++ YE E
Sbjct: 662 RANSLAAALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKL-KNAYE-EA 719
Query: 560 VARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
+ + E ++ + L+ +A+ E I + + LEK+++++ E D+QL ++
Sbjct: 720 LDQLETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALE 773
Score = 59.7 bits (138), Expect = 1e-08
Identities = 45/212 (21%), Positives = 104/212 (49%), Gaps = 10/212 (4%)
Frame = +2
Query: 74 EKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAK 253
E+ + + + D ++ ++ + A+ EK ++LQ ++ ++ + AN LD +
Sbjct: 615 EEAQEKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQ 674
Query: 254 KKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLE 433
+ ++ + EE+++++ K SL+T+L K +E + T+ + +NLE
Sbjct: 675 RNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVKRENKNLE 734
Query: 434 HDLDNIREQVEEEAEGKADLQR-----QLSKANAEAQLWRS----KYESEGVARSE-ELE 583
++ ++ EQ+ E + +L++ +L KA+ + L + ++E + R + EL
Sbjct: 735 QEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHEEAKILRIQLELT 794
Query: 584 EAKRKLQARLAEAEETIESLNQKVVALEKTKQ 679
+ K ++ ++AE +E IE L + +T Q
Sbjct: 795 QVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQ 826
Score = 54.0 bits (124), Expect = 6e-07
Identities = 48/215 (22%), Positives = 103/215 (47%), Gaps = 8/215 (3%)
Frame = +2
Query: 101 EVNDLRAGLDHLSNEKAAQ-EKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENS 277
E+ +++ +D EK + E++ + Q + +QS D R+ N+ KKK+ + +
Sbjct: 792 ELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKKKMEGDLN 851
Query: 278 DLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLAD------EEARERATLLGKFRN-LEH 436
++ QL A Q ++ K S+ QL+DT+ D E+ +E+ ++ + N L+
Sbjct: 852 EIEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALQTQEDLKEQLAIVERRANLLQA 911
Query: 437 DLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLA 616
+++ +R +E+ + +++L +N QL ++ S + ++LE +LQ+ +
Sbjct: 912 EVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSL-IHTKKKLETDLMQLQSEVE 970
Query: 617 EAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
+A + +K +K A E+L+ E D
Sbjct: 971 DASRDARNAEEKA---KKAITDAAMMAEELKKEQD 1002
Score = 52.4 bits (120), Expect = 2e-06
Identities = 54/263 (20%), Positives = 113/263 (42%), Gaps = 29/263 (11%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVK--------- 172
V D+ L+Q KL+ E+ + + ++ + + L N+K ++ +K
Sbjct: 259 VEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQL 318
Query: 173 ------------QLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQV 316
Q Q ++ E+Q++ +E + A + K + SD R+LEE ++
Sbjct: 319 QSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERL 378
Query: 317 SQ---LSKIKVSLTTQLE----DTKRLADEEARERATLLGKFRNLEHD-LDNIREQVEEE 472
+ ++ ++ L + E +R +E + ++ R D + + EQ++
Sbjct: 379 EEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVATLRKKHADSVAELGEQIDNL 438
Query: 473 AEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQK 652
K L+++ S+ E S ES +++ LE+ R L+ +L+EA E + +
Sbjct: 439 QRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKA-NLEKICRTLEDQLSEARGKNEEIQRS 497
Query: 653 VVALEKTKQRLATEVEDLQLEVD 721
+ L K RL TE +L +++
Sbjct: 498 LSELTTQKSRLQTEAGELSRQLE 520
Score = 48.0 bits (109), Expect = 4e-05
Identities = 40/169 (23%), Positives = 76/169 (44%), Gaps = 2/169 (1%)
Frame = +2
Query: 29 MGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSN-EKAAQEKIVKQLQHQLNEVQS 205
M E+L + A E+ + V DL+ LD +K +++L+ ++ E++
Sbjct: 993 MAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLETRIRELEF 1052
Query: 206 KADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADE 385
+ + + + +K +L Q EE V +L + L +++ KR A+E
Sbjct: 1053 ELEGEQKKNTESVKGLRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKVKSYKRQAEE 1112
Query: 386 EARERATLLGKFRNLEHDLDNIREQVEEEAEGKADL-QRQLSKANAEAQ 529
+ L KFR +H+L EEAE +AD+ + Q++K A+ +
Sbjct: 1113 ADEQANAHLTKFRKAQHEL--------EEAEERADIAESQVNKLRAKTR 1153
Score = 41.1 bits (92), Expect = 0.004
Identities = 63/267 (23%), Positives = 112/267 (41%), Gaps = 28/267 (10%)
Frame = +2
Query: 2 NSAGRFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLD----HLSNEKAAQEKIV 169
N A R M L+++ + A + A+ + ++ L HL + QE +
Sbjct: 837 NEAIRLKKKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALQTQEDLK 896
Query: 170 KQL---QHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKV 340
+QL + + N +Q++ +E TL + A+K E D +++ +Q + L K
Sbjct: 897 EQLAIVERRANLLQAEVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSLIHTKK 956
Query: 341 SLTTQL-------EDTKR---LADEEARERAT---LLGKFRNLEHDLDNIREQVEEEAEG 481
L T L ED R A+E+A++ T ++ + E D E++++ E
Sbjct: 957 KLETDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQ 1016
Query: 482 KA-DLQRQLSKANAEAQLWRSKYESEGVARSEELE-----EAKRKLQA--RLAEAEETIE 637
DLQ +L +A A K + R ELE E K+ ++ L + E ++
Sbjct: 1017 TVKDLQHRLDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRKYERRVK 1076
Query: 638 SLNQKVVALEKTKQRLATEVEDLQLEV 718
L + K RL V+ LQ++V
Sbjct: 1077 ELTYQSEEDRKNVLRLQDLVDKLQVKV 1103
>BC126409-1|AAI26410.1| 1941|Homo sapiens myosin, heavy chain 2,
skeletal muscle, adult protein.
Length = 1941
Score = 225 bits (551), Expect = 1e-58
Identities = 110/235 (46%), Positives = 162/235 (68%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
V+++GEQ+D L ++K K EK +++ E++DL + ++ +S K EK+ + L+ QL+E+
Sbjct: 1206 VAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSEL 1265
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
+SK +E R +NDL A + +L E+ + RQL+E E+ VSQLS+ K + T Q+E+ KR
Sbjct: 1266 KSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQL 1325
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEG 559
+EE + + L ++ HD D +REQ EEE E KA+LQR LSKAN E WR+KYE++
Sbjct: 1326 EEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDA 1385
Query: 560 VARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
+ R+EELEEAK+KL RL AEE +E++N K +LEKTKQRL EVEDL L+V+R
Sbjct: 1386 IQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVER 1440
Score = 72.9 bits (171), Expect = 1e-12
Identities = 58/235 (24%), Positives = 105/235 (44%), Gaps = 1/235 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+ D+ + D++N L K + + +V+DL L+ + E+ ++L+ L
Sbjct: 1013 LDDLQAEEDKVNTLT----KAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLA 1068
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
Q + LD KK E S+L ++E+ ++ QL K L ++E+ +
Sbjct: 1069 QESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEI 1128
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLS-KANAEAQLWRSKYESE 556
+ E RA + +L +L+ I E++ EEA G Q +++ K AE Q R E
Sbjct: 1129 EAERASRAKAEKQRSDLSRELEEISERL-EEAGGATSAQIEMNKKREAEFQKMRRDLEEA 1187
Query: 557 GVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
+ ++K +AE E I++L + LEK K + E++DL V+
Sbjct: 1188 TLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVE 1242
Score = 62.1 bits (144), Expect = 2e-09
Identities = 50/231 (21%), Positives = 102/231 (44%), Gaps = 1/231 (0%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQ-EKIVKQLQHQLNEVQSKA 211
EQ ++ + KA+ ++ ++ +EV R + + ++ + E+ K+L +L +
Sbjct: 1351 EQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHV 1410
Query: 212 DEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEA 391
+ N L+ K++L E DL+ +E + + L K + + L + K+ +E
Sbjct: 1411 EAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEETH 1470
Query: 392 RERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARS 571
E + R+L +L I+ EE + L+R+ E + +EG R
Sbjct: 1471 AELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQI-AEGGKRI 1529
Query: 572 EELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
ELE+ K++++ E + +E + E R+ E+ ++ EVDR
Sbjct: 1530 HELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDR 1580
Score = 60.5 bits (140), Expect = 7e-09
Identities = 51/236 (21%), Positives = 113/236 (47%), Gaps = 2/236 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
++D E+ DQL K K + E EV + + ++ E A+++ +L+ + +E+
Sbjct: 904 LADAEERCDQLIKTKIQLEAK----IKEVTERAEDEEEINAELTAKKR---KLEDECSEL 956
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
+ D+ TL ++ K + +L ++ + +++L+K K +L + T L
Sbjct: 957 KKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQT--LD 1014
Query: 380 DEEARE-RATLLGKFR-NLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYES 553
D +A E + L K + LE +D++ +E+E + + DL+R K + +L +
Sbjct: 1015 DLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESI-M 1073
Query: 554 EGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
+ ++L+E +K + ++ + IE + L+K + L +E+L+ E++
Sbjct: 1074 DIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIE 1129
Score = 57.6 bits (133), Expect = 5e-08
Identities = 51/239 (21%), Positives = 103/239 (43%), Gaps = 7/239 (2%)
Frame = +2
Query: 14 RFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLN 193
R V M LD + + A + + + ++N++ L+H + A + + Q L
Sbjct: 1598 RIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILK 1657
Query: 194 EVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKR 373
+ Q D+A R+ DL + + L ++EE + + Q + + +L D
Sbjct: 1658 DTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASE 1717
Query: 374 LADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRS--KY 547
+ +L+ + LE D+ ++ ++E+ + + + + KA +A + K
Sbjct: 1718 RVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKK 1777
Query: 548 ESEGVARSE----ELEEAKRKLQARLAEAEE-TIESLNQKVVALEKTKQRLATEVEDLQ 709
E + A E +E+ + LQ RL EAE+ ++ +++ LE + L EVE Q
Sbjct: 1778 EQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQ 1836
Score = 57.2 bits (132), Expect = 6e-08
Identities = 55/238 (23%), Positives = 112/238 (47%), Gaps = 4/238 (1%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFS--EVNDLRAGLDHLSNEKAAQEKIVKQLQHQLN 193
+ ++ QL++ ++KAK A S + + LR + KA ++ + + ++
Sbjct: 1318 IEELKRQLEE--EIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVA 1375
Query: 194 EVQSKAD-EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTK 370
+ ++K + +A + +L+ AKKKL+ +E ++ + L K K L ++ED
Sbjct: 1376 QWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLM 1435
Query: 371 RLADEEARERATLLGKFRNLEHDLDNIREQVEE-EAEGKADLQRQLSKANAEAQLWRSKY 547
+ A L K RN + L +++ EE AE +A Q++ E ++ Y
Sbjct: 1436 LDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEAS-QKEARSLGTELFKIKNAY 1494
Query: 548 ESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
E E + + E L+ + LQ +++ E I +++ LEK K+++ E +LQ ++
Sbjct: 1495 E-ESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALE 1551
Score = 57.2 bits (132), Expect = 6e-08
Identities = 45/235 (19%), Positives = 105/235 (44%), Gaps = 1/235 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
V D+ +++ N A +K + + + + + + E A +K + L +L ++
Sbjct: 1431 VEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKI 1490
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
++ +E+ L L K L E SDL Q+ E ++ +L KIK + + + +
Sbjct: 1491 KNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAAL 1550
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAE-AQLWRSKYESE 556
+E GK ++ +L+ ++ +V+ + K + QL + + + +S ++E
Sbjct: 1551 EEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAE 1610
Query: 557 GVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
+R++ + K+K++ L E E + N+ + + ++D Q+ +D
Sbjct: 1611 IRSRNDAI-RLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLD 1664
Score = 55.2 bits (127), Expect = 3e-07
Identities = 46/202 (22%), Positives = 99/202 (49%), Gaps = 13/202 (6%)
Frame = +2
Query: 113 LRAGLDHLS--NEKAAQ-EKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDL 283
L+A +H+ N K A EK ++LQ+++ ++ + N LD ++ ++
Sbjct: 1403 LQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEW 1462
Query: 284 LRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQV 463
++ EE +++ K SL T+L K +E + TL + +NL+ ++ ++ EQ+
Sbjct: 1463 KQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQI 1522
Query: 464 EEEAEGKADLQ---RQLSKANAEAQLWRSKYES-----EG-VARSE-ELEEAKRKLQARL 613
E + +L+ +Q+ + E Q + E+ EG + R + EL + K ++ ++
Sbjct: 1523 AEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKI 1582
Query: 614 AEAEETIESLNQKVVALEKTKQ 679
AE +E I+ L + + + ++ Q
Sbjct: 1583 AEKDEEIDQLKRNHIRIVESMQ 1604
Score = 54.8 bits (126), Expect = 3e-07
Identities = 43/178 (24%), Positives = 82/178 (46%), Gaps = 2/178 (1%)
Frame = +2
Query: 29 MGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSN-EKAAQEKIVKQLQHQLNEVQS 205
M E+L + A E+ + V DL+ LD +K +++L+ ++ E++
Sbjct: 1771 MAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEG 1830
Query: 206 KADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADE 385
+ + + + +K +L Q EE + +L + L +++ KR A+E
Sbjct: 1831 EVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEE 1890
Query: 386 EARERATLLGKFRNLEHDLDNIREQVEEEAEGKADL-QRQLSKANAEAQLWRSKYESE 556
+ T L KFR L+H+L EEAE +AD+ + Q++K +++ +K SE
Sbjct: 1891 AEEQSNTNLAKFRKLQHEL--------EEAEERADIAESQVNKLRVKSREVHTKVISE 1940
Score = 50.4 bits (115), Expect = 7e-06
Identities = 46/226 (20%), Positives = 98/226 (43%), Gaps = 2/226 (0%)
Frame = +2
Query: 26 DMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNE-KAAQEKIVKQLQHQLNEVQ 202
D E++ L+ + + ++++ ++ ++ + E + A+EK K + +
Sbjct: 1714 DASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAE 1773
Query: 203 SKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVS-LTTQLEDTKRLA 379
E + + + L+ KK + DL +L+EAE + K ++ L ++ + +
Sbjct: 1774 ELKKEQDTSAH-LERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEV 1832
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEG 559
+ E + A + R E + + Q EE+ + LQ + K A+ + ++ + E
Sbjct: 1833 ESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAE 1892
Query: 560 VARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEV 697
+ L + RKLQ L EAEE + +V L + + T+V
Sbjct: 1893 EQSNTNLAKF-RKLQHELEEAEERADIAESQVNKLRVKSREVHTKV 1937
Score = 48.0 bits (109), Expect = 4e-05
Identities = 61/250 (24%), Positives = 106/250 (42%), Gaps = 17/250 (6%)
Frame = +2
Query: 26 DMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQL---QHQLNE 196
D+ E QLN A + Y + L+ HL + +QE + +QL + + N
Sbjct: 1627 DLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANL 1686
Query: 197 VQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTT-------Q 355
+Q++ +E TL + ++K E D +++ +Q + L K L T +
Sbjct: 1687 LQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGE 1746
Query: 356 LEDT---KRLADEEARERAT---LLGKFRNLEHDLDNIREQVEEEAEGKA-DLQRQLSKA 514
+ED R A+E+A++ T ++ + E D E++++ E DLQ +L +A
Sbjct: 1747 MEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEA 1806
Query: 515 NAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATE 694
A K + AR ELE Q R AEA + + ++V L +
Sbjct: 1807 EQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKN 1866
Query: 695 VEDLQLEVDR 724
+ LQ VD+
Sbjct: 1867 ILRLQDLVDK 1876
>BC114545-1|AAI14546.1| 1939|Homo sapiens myosin, heavy chain 1,
skeletal muscle, adult protein.
Length = 1939
Score = 225 bits (551), Expect = 1e-58
Identities = 106/235 (45%), Positives = 165/235 (70%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
V+++GEQ+D L ++K K EK +++ E++DL + ++ +S K EK+ + L+ QL+E+
Sbjct: 1204 VAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEI 1263
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
++K +E R +NDL A + +L E+ + RQL+E ++ VSQLS+ K + T Q+E+ KR
Sbjct: 1264 KTKEEEQQRLINDLTAQRARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQL 1323
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEG 559
+EE + ++ L ++ HD D +REQ EEE E KA+LQR +SKAN+E WR+KYE++
Sbjct: 1324 EEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDA 1383
Query: 560 VARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
+ R+EELEEAK+KL RL +AEE +E++N K +LEKTKQRL EVEDL ++V+R
Sbjct: 1384 IQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVER 1438
Score = 72.1 bits (169), Expect = 2e-12
Identities = 57/230 (24%), Positives = 102/230 (44%), Gaps = 1/230 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+ D+ + D++N L K + + +V+DL L+ + E+ ++L+ L
Sbjct: 1011 LDDLQAEEDKVNTLT----KAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLA 1066
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
Q + LD KK E S L ++E+ ++ QL K L ++E+ +
Sbjct: 1067 QESTMDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEI 1126
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLS-KANAEAQLWRSKYESE 556
+ E RA + +L +L+ I E++ EEA G Q +++ K AE Q R E
Sbjct: 1127 EAERASRAKAEKQRSDLSRELEEISERL-EEAGGATSAQIEMNKKREAEFQKMRRDLEEA 1185
Query: 557 GVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDL 706
+ ++K +AE E I++L + LEK K + E++DL
Sbjct: 1186 TLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDL 1235
Score = 61.3 bits (142), Expect = 4e-09
Identities = 55/238 (23%), Positives = 115/238 (48%), Gaps = 4/238 (1%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFS--EVNDLRAGLDHLSNEKAAQEKIVKQLQHQLN 193
+ ++ QL++ ++KAK+ A S + + LR + KA ++ + + ++
Sbjct: 1316 IEELKRQLEE--EIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQRAMSKANSEVA 1373
Query: 194 EVQSKAD-EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTK 370
+ ++K + +A + +L+ AKKKL+ D +E ++ + L K K L ++ED
Sbjct: 1374 QWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLM 1433
Query: 371 RLADEEARERATLLGKFRNLEHDLDNIREQVEE-EAEGKADLQRQLSKANAEAQLWRSKY 547
+ A L K RN + L +++ EE AE +A Q++ + E ++ Y
Sbjct: 1434 IDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEAS-QKESRSLSTELFKIKNAY 1492
Query: 548 ESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
E E + + E L+ + LQ +++ E I +++ L+K K+++ E +LQ ++
Sbjct: 1493 E-ESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELKKIKKQVEQEKSELQAALE 1549
Score = 59.7 bits (138), Expect = 1e-08
Identities = 45/235 (19%), Positives = 105/235 (44%), Gaps = 1/235 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
V D+ +++ N A +K + + + + + + E A +K + L +L ++
Sbjct: 1429 VEDLMIDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKESRSLSTELFKI 1488
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
++ +E+ L L K L E SDL Q+ E ++ +L KIK + + + +
Sbjct: 1489 KNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELKKIKKQVEQEKSELQAAL 1548
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAE-AQLWRSKYESE 556
+E GK ++ +L+ ++ +V+ + K + Q+ + + + +S ++E
Sbjct: 1549 EEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQMKRNHIRIVESMQSTLDAE 1608
Query: 557 GVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
+R++ + K+K++ L E E + N+ + + ++D QL +D
Sbjct: 1609 IRSRNDAI-RLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQAILKDTQLHLD 1662
Score = 59.7 bits (138), Expect = 1e-08
Identities = 47/237 (19%), Positives = 102/237 (43%), Gaps = 1/237 (0%)
Frame = +2
Query: 14 RFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLN 193
R V M LD + + A + + + ++N++ L+H + A + + Q L
Sbjct: 1596 RIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQAILK 1655
Query: 194 EVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKR 373
+ Q D+A R+ DL + + L ++EE + + Q + + +L D
Sbjct: 1656 DTQLHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASE 1715
Query: 374 LADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYES 553
+ +L+ + LE D+ I+ ++E+ + + + + KA +A + + +
Sbjct: 1716 RVQLLHTQNTSLINTKKKLETDISQIQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKK 1775
Query: 554 EGVARSEELEEAKRKLQARLAEAEETIESLNQKVV-ALEKTKQRLATEVEDLQLEVD 721
E S LE K+ L+ + + + ++ Q + +K Q+L V +L+ EV+
Sbjct: 1776 E-QDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVE 1831
Score = 58.8 bits (136), Expect = 2e-08
Identities = 53/237 (22%), Positives = 114/237 (48%), Gaps = 3/237 (1%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
++D E+ DQL K K + E EV + + ++ E A+++ +L+ + +E+
Sbjct: 902 LADAEERCDQLIKTKIQLEAK----IKEVTERAEDEEEINAELTAKKR---KLEDECSEL 954
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
+ D+ TL ++ K + +L ++ + +++L+K K +L + T L
Sbjct: 955 KKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQT--LD 1012
Query: 380 DEEARE-RATLLGKFR-NLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQL-WRSKYE 550
D +A E + L K + LE +D++ +E+E + + DL+R K + +L S +
Sbjct: 1013 DLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESTMD 1072
Query: 551 SEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
E ++L+E +K + ++ + IE + L+K + L +E+L+ E++
Sbjct: 1073 IEN--DKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIE 1127
Score = 57.2 bits (132), Expect = 6e-08
Identities = 42/212 (19%), Positives = 105/212 (49%), Gaps = 10/212 (4%)
Frame = +2
Query: 74 EKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAK 253
E+ + + + D ++ ++ + A+ EK ++LQ+++ ++ + N LD +
Sbjct: 1391 EEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQ 1450
Query: 254 KKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLE 433
+ ++ ++ EE +++ K SL+T+L K +E + TL + +NL+
Sbjct: 1451 RNFDKILAEWKQKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQ 1510
Query: 434 HDLDNIREQVEEEAEGKADL---QRQLSKANAEAQLWRSKYES-----EG-VARSE-ELE 583
++ ++ EQ+ E + +L ++Q+ + +E Q + E+ EG + R + EL
Sbjct: 1511 QEISDLTEQIAEGGKRIHELKKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLELN 1570
Query: 584 EAKRKLQARLAEAEETIESLNQKVVALEKTKQ 679
+ K ++ ++AE +E I+ + + + + ++ Q
Sbjct: 1571 QVKSEVDRKIAEKDEEIDQMKRNHIRIVESMQ 1602
Score = 51.6 bits (118), Expect = 3e-06
Identities = 41/178 (23%), Positives = 82/178 (46%), Gaps = 2/178 (1%)
Frame = +2
Query: 29 MGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSN-EKAAQEKIVKQLQHQLNEVQS 205
M E+L + A E+ + V DL+ LD +K +++L+ ++ E++
Sbjct: 1769 MAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEG 1828
Query: 206 KADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADE 385
+ + + + +K + +L Q EE + +L + L +++ KR A+E
Sbjct: 1829 EVESEQKRNVEAVKGLRKHERKVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEE 1888
Query: 386 EARERATLLGKFRNLEHDLDNIREQVEEEAEGKADL-QRQLSKANAEAQLWRSKYESE 556
+ L KFR ++H+L EEAE +AD+ + Q++K +++ +K SE
Sbjct: 1889 AEEQSNVNLSKFRRIQHEL--------EEAEERADIAESQVNKLRVKSREVHTKIISE 1938
Score = 47.2 bits (107), Expect = 7e-05
Identities = 61/250 (24%), Positives = 105/250 (42%), Gaps = 17/250 (6%)
Frame = +2
Query: 26 DMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQL---QHQLNE 196
D+ E QLN A + Y + L+ HL + +QE + +QL + + N
Sbjct: 1625 DLNEMEIQLNHANRMAAEALRNYRNTQAILKDTQLHLDDALRSQEDLKEQLAMVERRANL 1684
Query: 197 VQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTT-------Q 355
+Q++ +E TL + ++K E D +++ +Q + L K L T +
Sbjct: 1685 LQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGE 1744
Query: 356 LEDT---KRLADEEARERAT---LLGKFRNLEHDLDNIREQVEEEAEGKA-DLQRQLSKA 514
+ED R A+E+A++ T ++ + E D E++++ E DLQ +L +A
Sbjct: 1745 MEDIIQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEA 1804
Query: 515 NAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATE 694
A K + AR ELE Q R EA + + +KV L +
Sbjct: 1805 EQLALKGGKKQIQKLEARVRELEGEVESEQKRNVEAVKGLRKHERKVKELTYQTEEDRKN 1864
Query: 695 VEDLQLEVDR 724
+ LQ VD+
Sbjct: 1865 ILRLQDLVDK 1874
>AF111785-1|AAD29951.1| 1939|Homo sapiens myosin heavy chain IIx/d
protein.
Length = 1939
Score = 225 bits (551), Expect = 1e-58
Identities = 106/235 (45%), Positives = 165/235 (70%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
V+++GEQ+D L ++K K EK +++ E++DL + ++ +S K EK+ + L+ QL+E+
Sbjct: 1204 VAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEI 1263
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
++K +E R +NDL A + +L E+ + RQL+E ++ VSQLS+ K + T Q+E+ KR
Sbjct: 1264 KTKEEEQQRLINDLTAQRARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQL 1323
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEG 559
+EE + ++ L ++ HD D +REQ EEE E KA+LQR +SKAN+E WR+KYE++
Sbjct: 1324 EEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDA 1383
Query: 560 VARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
+ R+EELEEAK+KL RL +AEE +E++N K +LEKTKQRL EVEDL ++V+R
Sbjct: 1384 IQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVER 1438
Score = 73.7 bits (173), Expect = 7e-13
Identities = 58/230 (25%), Positives = 103/230 (44%), Gaps = 1/230 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+ D+ + D++N L K + + +V+DL L+ + E+ ++L+ L
Sbjct: 1011 LDDLQAEEDKVNTLT----KAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLA 1066
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
Q A + LD KK E S L ++E+ ++ QL K L ++E+ +
Sbjct: 1067 QESAMDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEI 1126
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLS-KANAEAQLWRSKYESE 556
+ E RA + +L +L+ I E++ EEA G Q +++ K AE Q R E
Sbjct: 1127 EAERASRAKAEKQRSDLSRELEEISERL-EEAGGATSAQIEMNKKREAEFQKMRRDLEEA 1185
Query: 557 GVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDL 706
+ ++K +AE E I++L + LEK K + E++DL
Sbjct: 1186 TLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDL 1235
Score = 66.1 bits (154), Expect = 1e-10
Identities = 51/231 (22%), Positives = 104/231 (45%), Gaps = 1/231 (0%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQ-EKIVKQLQHQLNEVQSKA 211
EQ ++ + KA+ ++ ++ SEV R + + ++ + E+ K+L +L + +
Sbjct: 1349 EQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHV 1408
Query: 212 DEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEA 391
+ N L+ K++L E DL+ +E + + L K + + L + K+ +E
Sbjct: 1409 EAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQKCEETH 1468
Query: 392 RERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARS 571
E + R+L +L I+ EE + L+R+ E + +EG R
Sbjct: 1469 AELEASQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQI-AEGGKRI 1527
Query: 572 EELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
ELE+ K++++ +E + +E + E R+ E+ ++ EVDR
Sbjct: 1528 HELEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDR 1578
Score = 62.9 bits (146), Expect = 1e-09
Identities = 56/238 (23%), Positives = 115/238 (48%), Gaps = 4/238 (1%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFS--EVNDLRAGLDHLSNEKAAQEKIVKQLQHQLN 193
+ ++ QL++ ++KAK+ A S + + LR + KA ++ + + ++
Sbjct: 1316 IEELKRQLEE--EIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQRAMSKANSEVA 1373
Query: 194 EVQSKAD-EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTK 370
+ ++K + +A + +L+ AKKKL+ D +E ++ + L K K L ++ED
Sbjct: 1374 QWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLM 1433
Query: 371 RLADEEARERATLLGKFRNLEHDLDNIREQVEE-EAEGKADLQRQLSKANAEAQLWRSKY 547
+ A L K RN + L +++ EE AE +A Q++ + E ++ Y
Sbjct: 1434 IDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEAS-QKESRSLSTELFKIKNAY 1492
Query: 548 ESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
E E + + E L+ + LQ +++ E I +++ LEK K+++ E +LQ ++
Sbjct: 1493 E-ESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAALE 1549
Score = 59.7 bits (138), Expect = 1e-08
Identities = 45/235 (19%), Positives = 105/235 (44%), Gaps = 1/235 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
V D+ +++ N A +K + + + + + + E A +K + L +L ++
Sbjct: 1429 VEDLMIDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKESRSLSTELFKI 1488
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
++ +E+ L L K L E SDL Q+ E ++ +L KIK + + + +
Sbjct: 1489 KNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAAL 1548
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAE-AQLWRSKYESE 556
+E GK ++ +L+ ++ +V+ + K + Q+ + + + +S ++E
Sbjct: 1549 EEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQMKRNHIRIVESMQSTLDAE 1608
Query: 557 GVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
+R++ + K+K++ L E E + N+ + + ++D QL +D
Sbjct: 1609 IRSRNDAI-RLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQAILKDTQLHLD 1662
Score = 59.7 bits (138), Expect = 1e-08
Identities = 47/237 (19%), Positives = 102/237 (43%), Gaps = 1/237 (0%)
Frame = +2
Query: 14 RFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLN 193
R V M LD + + A + + + ++N++ L+H + A + + Q L
Sbjct: 1596 RIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQAILK 1655
Query: 194 EVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKR 373
+ Q D+A R+ DL + + L ++EE + + Q + + +L D
Sbjct: 1656 DTQLHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASE 1715
Query: 374 LADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYES 553
+ +L+ + LE D+ I+ ++E+ + + + + KA +A + + +
Sbjct: 1716 RVQLLHTQNTSLINTKKKLETDISQIQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKK 1775
Query: 554 EGVARSEELEEAKRKLQARLAEAEETIESLNQKVV-ALEKTKQRLATEVEDLQLEVD 721
E S LE K+ L+ + + + ++ Q + +K Q+L V +L+ EV+
Sbjct: 1776 E-QDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVE 1831
Score = 58.8 bits (136), Expect = 2e-08
Identities = 53/237 (22%), Positives = 114/237 (48%), Gaps = 3/237 (1%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
++D E+ DQL K K + E EV + + ++ E A+++ +L+ + +E+
Sbjct: 902 LADAEERCDQLIKTKIQLEAK----IKEVTERAEDEEEINAELTAKKR---KLEDECSEL 954
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
+ D+ TL ++ K + +L ++ + +++L+K K +L + T L
Sbjct: 955 KKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQT--LD 1012
Query: 380 DEEARE-RATLLGKFR-NLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQL-WRSKYE 550
D +A E + L K + LE +D++ +E+E + + DL+R K + +L S +
Sbjct: 1013 DLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESAMD 1072
Query: 551 SEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
E ++L+E +K + ++ + IE + L+K + L +E+L+ E++
Sbjct: 1073 IEN--DKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIE 1127
Score = 57.6 bits (133), Expect = 5e-08
Identities = 42/212 (19%), Positives = 105/212 (49%), Gaps = 10/212 (4%)
Frame = +2
Query: 74 EKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAK 253
E+ + + + D ++ ++ + A+ EK ++LQ+++ ++ + N LD +
Sbjct: 1391 EEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQ 1450
Query: 254 KKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLE 433
+ ++ ++ EE +++ K SL+T+L K +E + TL + +NL+
Sbjct: 1451 RNFDKILAEWKQKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQ 1510
Query: 434 HDLDNIREQVEEEAEGKADLQ---RQLSKANAEAQLWRSKYES-----EG-VARSE-ELE 583
++ ++ EQ+ E + +L+ +Q+ + +E Q + E+ EG + R + EL
Sbjct: 1511 QEISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLELN 1570
Query: 584 EAKRKLQARLAEAEETIESLNQKVVALEKTKQ 679
+ K ++ ++AE +E I+ + + + + ++ Q
Sbjct: 1571 QVKSEVDRKIAEKDEEIDQMKRNHIRIVESMQ 1602
Score = 51.6 bits (118), Expect = 3e-06
Identities = 41/178 (23%), Positives = 82/178 (46%), Gaps = 2/178 (1%)
Frame = +2
Query: 29 MGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSN-EKAAQEKIVKQLQHQLNEVQS 205
M E+L + A E+ + V DL+ LD +K +++L+ ++ E++
Sbjct: 1769 MAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEG 1828
Query: 206 KADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADE 385
+ + + + +K + +L Q EE + +L + L +++ KR A+E
Sbjct: 1829 EVESEQKRNVEAVKGLRKHERKVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEE 1888
Query: 386 EARERATLLGKFRNLEHDLDNIREQVEEEAEGKADL-QRQLSKANAEAQLWRSKYESE 556
+ L KFR ++H+L EEAE +AD+ + Q++K +++ +K SE
Sbjct: 1889 AEEQSNVNLSKFRRIQHEL--------EEAEERADIAESQVNKLRVKSREVHTKIISE 1938
Score = 47.2 bits (107), Expect = 7e-05
Identities = 61/250 (24%), Positives = 105/250 (42%), Gaps = 17/250 (6%)
Frame = +2
Query: 26 DMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQL---QHQLNE 196
D+ E QLN A + Y + L+ HL + +QE + +QL + + N
Sbjct: 1625 DLNEMEIQLNHANRMAAEALRNYRNTQAILKDTQLHLDDALRSQEDLKEQLAMVERRANL 1684
Query: 197 VQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTT-------Q 355
+Q++ +E TL + ++K E D +++ +Q + L K L T +
Sbjct: 1685 LQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGE 1744
Query: 356 LEDT---KRLADEEARERAT---LLGKFRNLEHDLDNIREQVEEEAEGKA-DLQRQLSKA 514
+ED R A+E+A++ T ++ + E D E++++ E DLQ +L +A
Sbjct: 1745 MEDIIQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEA 1804
Query: 515 NAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATE 694
A K + AR ELE Q R EA + + +KV L +
Sbjct: 1805 EQLALKGGKKQIQKLEARVRELEGEVESEQKRNVEAVKGLRKHERKVKELTYQTEEDRKN 1864
Query: 695 VEDLQLEVDR 724
+ LQ VD+
Sbjct: 1865 ILRLQDLVDK 1874
>AF111784-1|AAD29950.1| 1941|Homo sapiens myosin heavy chain IIa
protein.
Length = 1941
Score = 225 bits (551), Expect = 1e-58
Identities = 110/235 (46%), Positives = 162/235 (68%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
V+++GEQ+D L ++K K EK +++ E++DL + ++ +S K EK+ + L+ QL+E+
Sbjct: 1206 VAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSEL 1265
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
+SK +E R +NDL A + +L E+ + RQL+E E+ VSQLS+ K + T Q+E+ KR
Sbjct: 1266 KSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQL 1325
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEG 559
+EE + + L ++ HD D +REQ EEE E KA+LQR LSKAN E WR+KYE++
Sbjct: 1326 EEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDA 1385
Query: 560 VARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
+ R+EELEEAK+KL RL AEE +E++N K +LEKTKQRL EVEDL L+V+R
Sbjct: 1386 IQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVER 1440
Score = 72.9 bits (171), Expect = 1e-12
Identities = 58/235 (24%), Positives = 105/235 (44%), Gaps = 1/235 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+ D+ + D++N L K + + +V+DL L+ + E+ ++L+ L
Sbjct: 1013 LDDLQAEEDKVNTLT----KAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLA 1068
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
Q + LD KK E S+L ++E+ ++ QL K L ++E+ +
Sbjct: 1069 QESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEI 1128
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLS-KANAEAQLWRSKYESE 556
+ E RA + +L +L+ I E++ EEA G Q +++ K AE Q R E
Sbjct: 1129 EAERASRAKAEKQRSDLSRELEEISERL-EEAGGATSAQIEMNKKREAEFQKMRRDLEEA 1187
Query: 557 GVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
+ ++K +AE E I++L + LEK K + E++DL V+
Sbjct: 1188 TLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVE 1242
Score = 62.1 bits (144), Expect = 2e-09
Identities = 50/231 (21%), Positives = 102/231 (44%), Gaps = 1/231 (0%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQ-EKIVKQLQHQLNEVQSKA 211
EQ ++ + KA+ ++ ++ +EV R + + ++ + E+ K+L +L +
Sbjct: 1351 EQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHV 1410
Query: 212 DEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEA 391
+ N L+ K++L E DL+ +E + + L K + + L + K+ +E
Sbjct: 1411 EAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEETH 1470
Query: 392 RERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARS 571
E + R+L +L I+ EE + L+R+ E + +EG R
Sbjct: 1471 AELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQI-AEGGKRI 1529
Query: 572 EELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
ELE+ K++++ E + +E + E R+ E+ ++ EVDR
Sbjct: 1530 HELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDR 1580
Score = 60.5 bits (140), Expect = 7e-09
Identities = 51/236 (21%), Positives = 113/236 (47%), Gaps = 2/236 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
++D E+ DQL K K + E EV + + ++ E A+++ +L+ + +E+
Sbjct: 904 LADAEERCDQLIKTKIQLEAK----IKEVTERAEDEEEINAELTAKKR---KLEDECSEL 956
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
+ D+ TL ++ K + +L ++ + +++L+K K +L + T L
Sbjct: 957 KKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQT--LD 1014
Query: 380 DEEARE-RATLLGKFR-NLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYES 553
D +A E + L K + LE +D++ +E+E + + DL+R K + +L +
Sbjct: 1015 DLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESI-M 1073
Query: 554 EGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
+ ++L+E +K + ++ + IE + L+K + L +E+L+ E++
Sbjct: 1074 DIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIE 1129
Score = 57.6 bits (133), Expect = 5e-08
Identities = 51/239 (21%), Positives = 103/239 (43%), Gaps = 7/239 (2%)
Frame = +2
Query: 14 RFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLN 193
R V M LD + + A + + + ++N++ L+H + A + + Q L
Sbjct: 1598 RIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILK 1657
Query: 194 EVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKR 373
+ Q D+A R+ DL + + L ++EE + + Q + + +L D
Sbjct: 1658 DTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASE 1717
Query: 374 LADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRS--KY 547
+ +L+ + LE D+ ++ ++E+ + + + + KA +A + K
Sbjct: 1718 RVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKK 1777
Query: 548 ESEGVARSE----ELEEAKRKLQARLAEAEE-TIESLNQKVVALEKTKQRLATEVEDLQ 709
E + A E +E+ + LQ RL EAE+ ++ +++ LE + L EVE Q
Sbjct: 1778 EQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQ 1836
Score = 57.2 bits (132), Expect = 6e-08
Identities = 55/238 (23%), Positives = 112/238 (47%), Gaps = 4/238 (1%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFS--EVNDLRAGLDHLSNEKAAQEKIVKQLQHQLN 193
+ ++ QL++ ++KAK A S + + LR + KA ++ + + ++
Sbjct: 1318 IEELKRQLEE--EIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVA 1375
Query: 194 EVQSKAD-EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTK 370
+ ++K + +A + +L+ AKKKL+ +E ++ + L K K L ++ED
Sbjct: 1376 QWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLM 1435
Query: 371 RLADEEARERATLLGKFRNLEHDLDNIREQVEE-EAEGKADLQRQLSKANAEAQLWRSKY 547
+ A L K RN + L +++ EE AE +A Q++ E ++ Y
Sbjct: 1436 LDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEAS-QKEARSLGTELFKIKNAY 1494
Query: 548 ESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
E E + + E L+ + LQ +++ E I +++ LEK K+++ E +LQ ++
Sbjct: 1495 E-ESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALE 1551
Score = 57.2 bits (132), Expect = 6e-08
Identities = 45/235 (19%), Positives = 105/235 (44%), Gaps = 1/235 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
V D+ +++ N A +K + + + + + + E A +K + L +L ++
Sbjct: 1431 VEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKI 1490
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
++ +E+ L L K L E SDL Q+ E ++ +L KIK + + + +
Sbjct: 1491 KNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAAL 1550
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAE-AQLWRSKYESE 556
+E GK ++ +L+ ++ +V+ + K + QL + + + +S ++E
Sbjct: 1551 EEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAE 1610
Query: 557 GVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
+R++ + K+K++ L E E + N+ + + ++D Q+ +D
Sbjct: 1611 IRSRNDAI-RLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLD 1664
Score = 55.2 bits (127), Expect = 3e-07
Identities = 46/202 (22%), Positives = 99/202 (49%), Gaps = 13/202 (6%)
Frame = +2
Query: 113 LRAGLDHLS--NEKAAQ-EKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDL 283
L+A +H+ N K A EK ++LQ+++ ++ + N LD ++ ++
Sbjct: 1403 LQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEW 1462
Query: 284 LRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQV 463
++ EE +++ K SL T+L K +E + TL + +NL+ ++ ++ EQ+
Sbjct: 1463 KQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQI 1522
Query: 464 EEEAEGKADLQ---RQLSKANAEAQLWRSKYES-----EG-VARSE-ELEEAKRKLQARL 613
E + +L+ +Q+ + E Q + E+ EG + R + EL + K ++ ++
Sbjct: 1523 AEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKI 1582
Query: 614 AEAEETIESLNQKVVALEKTKQ 679
AE +E I+ L + + + ++ Q
Sbjct: 1583 AEKDEEIDQLKRNHIRIVESMQ 1604
Score = 54.8 bits (126), Expect = 3e-07
Identities = 43/178 (24%), Positives = 82/178 (46%), Gaps = 2/178 (1%)
Frame = +2
Query: 29 MGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSN-EKAAQEKIVKQLQHQLNEVQS 205
M E+L + A E+ + V DL+ LD +K +++L+ ++ E++
Sbjct: 1771 MAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEG 1830
Query: 206 KADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADE 385
+ + + + +K +L Q EE + +L + L +++ KR A+E
Sbjct: 1831 EVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEE 1890
Query: 386 EARERATLLGKFRNLEHDLDNIREQVEEEAEGKADL-QRQLSKANAEAQLWRSKYESE 556
+ T L KFR L+H+L EEAE +AD+ + Q++K +++ +K SE
Sbjct: 1891 AEEQSNTNLAKFRKLQHEL--------EEAEERADIAESQVNKLRVKSREVHTKVISE 1940
Score = 50.4 bits (115), Expect = 7e-06
Identities = 46/226 (20%), Positives = 98/226 (43%), Gaps = 2/226 (0%)
Frame = +2
Query: 26 DMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNE-KAAQEKIVKQLQHQLNEVQ 202
D E++ L+ + + ++++ ++ ++ + E + A+EK K + +
Sbjct: 1714 DASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAE 1773
Query: 203 SKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVS-LTTQLEDTKRLA 379
E + + + L+ KK + DL +L+EAE + K ++ L ++ + +
Sbjct: 1774 ELKKEQDTSAH-LERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEV 1832
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEG 559
+ E + A + R E + + Q EE+ + LQ + K A+ + ++ + E
Sbjct: 1833 ESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAE 1892
Query: 560 VARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEV 697
+ L + RKLQ L EAEE + +V L + + T+V
Sbjct: 1893 EQSNTNLAKF-RKLQHELEEAEERADIAESQVNKLRVKSREVHTKV 1937
Score = 48.0 bits (109), Expect = 4e-05
Identities = 61/250 (24%), Positives = 106/250 (42%), Gaps = 17/250 (6%)
Frame = +2
Query: 26 DMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQL---QHQLNE 196
D+ E QLN A + Y + L+ HL + +QE + +QL + + N
Sbjct: 1627 DLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANL 1686
Query: 197 VQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTT-------Q 355
+Q++ +E TL + ++K E D +++ +Q + L K L T +
Sbjct: 1687 LQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGE 1746
Query: 356 LEDT---KRLADEEARERAT---LLGKFRNLEHDLDNIREQVEEEAEGKA-DLQRQLSKA 514
+ED R A+E+A++ T ++ + E D E++++ E DLQ +L +A
Sbjct: 1747 MEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEA 1806
Query: 515 NAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATE 694
A K + AR ELE Q R AEA + + ++V L +
Sbjct: 1807 EQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKN 1866
Query: 695 VEDLQLEVDR 724
+ LQ VD+
Sbjct: 1867 ILRLQDLVDK 1876
>D00943-1|BAA00791.1| 1939|Homo sapiens cardiac alpha-myosin heavy
chain protein.
Length = 1939
Score = 225 bits (550), Expect = 1e-58
Identities = 108/235 (45%), Positives = 162/235 (68%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
V+++GEQ+D L ++K K EK ++++ E++D+ + ++ + KA EK+ + L+ Q NE
Sbjct: 1202 VAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEY 1261
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
+ K +EA R+LND + KL EN +L RQLEE E+ +SQL++ K+S T Q+ED KR
Sbjct: 1262 RVKLEEAQRSLNDFTTQRAKLQTENGELSRQLEEKEALISQLTRGKLSYTQQMEDLKRQL 1321
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEG 559
+EE + + L ++ HD D +REQ EEE E KA+LQR LSKAN+E R+KYE++
Sbjct: 1322 EEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQCRTKYETDA 1381
Query: 560 VARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
+ R+EELEEAK+KL RL +AEE +E++N K +LEKTK RL E+EDL ++V+R
Sbjct: 1382 IQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVER 1436
Score = 71.3 bits (167), Expect = 4e-12
Identities = 50/237 (21%), Positives = 107/237 (45%), Gaps = 1/237 (0%)
Frame = +2
Query: 14 RFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLN 193
R V + LD + + + + + + ++N++ L H + A +K VK LQ L
Sbjct: 1594 RVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLK 1653
Query: 194 EVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKR 373
+ Q + D+A R +DL + N+ L +LEE + V Q + + +L +T
Sbjct: 1654 DTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLADRELIETSE 1713
Query: 374 LADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYES 553
+ +L+ + + ++ DL ++ +VEE + + + + KA A + + +
Sbjct: 1714 RVQLLHSQNTSLINQKKKMDADLSQLQSEVEEAVQECRNAEEKAKKAITHAAMMAEELKK 1773
Query: 554 EGVARSEELEEAKRKLQARLAEAEETIESLNQ-KVVALEKTKQRLATEVEDLQLEVD 721
E S LE K+ ++ + + + ++ Q + +K Q+L V +L+ E++
Sbjct: 1774 E-QDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEGELE 1829
Score = 67.3 bits (157), Expect = 6e-11
Identities = 53/233 (22%), Positives = 105/233 (45%), Gaps = 1/233 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+ D+ QL++ K K + + LR + + KA ++++ + ++ +
Sbjct: 1314 MEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQC 1373
Query: 200 QSKAD-EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRL 376
++K + +A + +L+ AKKKL+ D +E ++ S L K K L ++ED
Sbjct: 1374 RTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVD 1433
Query: 377 ADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESE 556
+ A L K RN + L +++ EE Q++ + E ++ YE E
Sbjct: 1434 VERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYE-E 1492
Query: 557 GVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLE 715
+ E + + LQ +++ E + + V LEK +++L EVE L+L+
Sbjct: 1493 SLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKVRKQL--EVEKLELQ 1543
Score = 60.9 bits (141), Expect = 5e-09
Identities = 53/238 (22%), Positives = 111/238 (46%), Gaps = 9/238 (3%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQ-EKIVKQLQHQLNEVQSKA 211
EQ ++ + KA+ ++ ++ SEV R + + ++ + E+ K+L +L + +
Sbjct: 1347 EQYEEETEAKAELQRVLSKANSEVAQCRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAV 1406
Query: 212 DEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEA 391
+ N + L+ K +L E DL+ +E + + + L K + + L + K+ +E
Sbjct: 1407 EAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQ 1466
Query: 392 RERATLLGKFRNLEHDLDNIREQVEEEAEG-------KADLQRQLSKANAE-AQLWRSKY 547
E + + R+L +L ++ EE E +LQ ++S + + ++ +
Sbjct: 1467 SELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVH 1526
Query: 548 ESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
E E V + E+E K +LQ+ L EAE ++E K++ + ++ E+E E D
Sbjct: 1527 ELEKVRKQLEVE--KLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKD 1582
Score = 58.8 bits (136), Expect = 2e-08
Identities = 51/216 (23%), Positives = 102/216 (47%), Gaps = 9/216 (4%)
Frame = +2
Query: 101 EVNDLRAGLDHLSNEKAAQ-EKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKK------ 259
E N ++A ++ EK + E+ + Q ++ +Q+ D R+ N++ KKK
Sbjct: 1566 EFNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLN 1625
Query: 260 -LSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRN-LE 433
+ I+ S R EA+ QV L + QL+D R A+++ +E ++ + N L+
Sbjct: 1626 EMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVR-ANDDLKENIAIVERRNNLLQ 1684
Query: 434 HDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARL 613
+L+ +R VE+ + R+L + + QL S+ S + + ++++ +LQ+ +
Sbjct: 1685 AELEELRAVVEQTERSRKLADRELIETSERVQLLHSQNTSL-INQKKKMDADLSQLQSEV 1743
Query: 614 AEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
EA + + +K +K A E+L+ E D
Sbjct: 1744 EEAVQECRNAEEKA---KKAITHAAMMAEELKKEQD 1776
Score = 56.0 bits (129), Expect = 1e-07
Identities = 41/233 (17%), Positives = 102/233 (43%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+ D E ++ +N + EK + + +E+ DL ++ + AA +K + L E
Sbjct: 1399 LQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEW 1458
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
+ K +E+ L + LS E L EE+ + + +L ++ D
Sbjct: 1459 KQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQL 1518
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEG 559
E + L + LE + ++ +EE + ++ +A E +++ E +
Sbjct: 1519 GEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKL 1578
Query: 560 VARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEV 718
+ EE+E+AKR Q + + ++++ + + + K+++ ++ ++++++
Sbjct: 1579 AEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQL 1631
Score = 53.2 bits (122), Expect = 1e-06
Identities = 68/267 (25%), Positives = 121/267 (45%), Gaps = 32/267 (11%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVK---QLQHQL 190
V ++ E++ L+++ AK K + + E + + LD L E+ + K +L+ Q+
Sbjct: 977 VKNLTEEMAGLDEIIAKLTKEK-KALQEAH--QQALDDLQAEEDKVNTLSKSKVKLEQQV 1033
Query: 191 NEVQSKADEANRTLNDLDAAKKKL------------SIENS--DLLRQLEEAESQVSQL- 325
++++ ++ + DL+ AK+KL +EN L +L++ E ++Q
Sbjct: 1034 DDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQN 1093
Query: 326 SKIKVSLTTQLEDTKRLADEEAR---------ERATLLGKFRNLEHDLDNIREQVE---E 469
SKI+ L+ K+L + +AR T K L DL E++ E
Sbjct: 1094 SKIEDEQVLALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLE 1153
Query: 470 EAEGKADLQRQLS-KANAEAQLWRSKYESEGVARSEELEEAKRKLQA-RLAEAEETIESL 643
EA G +Q +++ K AE Q R E E + E A RK A +AE E I++L
Sbjct: 1154 EAGGATSVQIEMNKKREAEFQKMRRDLE-EATLQHEATAAALRKKHADSVAELGEQIDNL 1212
Query: 644 NQKVVALEKTKQRLATEVEDLQLEVDR 724
+ LEK K E++D+ +++
Sbjct: 1213 QRVKQKLEKEKSEFKLELDDVTSNMEQ 1239
Score = 52.4 bits (120), Expect = 2e-06
Identities = 48/217 (22%), Positives = 90/217 (41%), Gaps = 1/217 (0%)
Frame = +2
Query: 74 EKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAK 253
E+ + + V+ L+ LD + + ++ K+++ LNE++ + ANR +
Sbjct: 1586 EQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQV 1645
Query: 254 KKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNL- 430
K L D QL++A L K +++ + + + EE R + R L
Sbjct: 1646 KSLQSLLKDTQIQLDDAVRANDDL-KENIAIVERRNNLLQAELEELRAVVEQTERSRKLA 1704
Query: 431 EHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQAR 610
+ +L E+V+ L Q K +A+ +S+ E E V EE +K
Sbjct: 1705 DRELIETSERVQLLHSQNTSLINQKKKMDADLSQLQSEVE-EAVQECRNAEEKAKKAITH 1763
Query: 611 LAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
A E ++ LE+ K+ + ++DLQ +D
Sbjct: 1764 AAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLD 1800
Score = 50.0 bits (114), Expect = 9e-06
Identities = 39/169 (23%), Positives = 80/169 (47%), Gaps = 2/169 (1%)
Frame = +2
Query: 29 MGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSN-EKAAQEKIVKQLQHQLNEVQS 205
M E+L + A E+ + + DL+ LD +K +++L+ ++ E++
Sbjct: 1767 MAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEG 1826
Query: 206 KADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADE 385
+ + + + +K +L Q EE + + +L + L +++ KR A+E
Sbjct: 1827 ELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLLRLQDLVDKLQLKVKAYKRQAEE 1886
Query: 386 EARERATLLGKFRNLEHDLDNIREQVEEEAEGKADL-QRQLSKANAEAQ 529
+ T L KFR ++H+LD EAE +AD+ + Q++K A+++
Sbjct: 1887 AEEQANTNLSKFRKVQHELD--------EAEERADIAESQVNKLRAKSR 1927
Score = 49.6 bits (113), Expect = 1e-05
Identities = 65/257 (25%), Positives = 119/257 (46%), Gaps = 24/257 (9%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDH-------LSNEKAAQEKIVKQL 178
+++M QL N++ A+A+K S + D + LD L A E+ L
Sbjct: 1624 LNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLL 1683
Query: 179 QHQLNEVQSKADE-------ANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQL-SKI 334
Q +L E+++ ++ A+R L + + L +N+ L+ Q ++ ++ +SQL S++
Sbjct: 1684 QAELEELRAVVEQTERSRKLADRELIETSERVQLLHSQNTSLINQKKKMDADLSQLQSEV 1743
Query: 335 K--VSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLS 508
+ V E+ + A A A L K ++ L+ +++ +E+ + DLQ +L
Sbjct: 1744 EEAVQECRNAEEKAKKAITHAAMMAEELKKEQDTSAHLERMKKNMEQTIK---DLQHRLD 1800
Query: 509 KANAEAQLWRSKYESEGVARSEELE---EAKRKLQAR----LAEAEETIESLNQKVVALE 667
+A A K + AR ELE EA++K A + ++E I+ L + +
Sbjct: 1801 EAEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDK 1860
Query: 668 KTKQRLATEVEDLQLEV 718
K RL V+ LQL+V
Sbjct: 1861 KNLLRLQDLVDKLQLKV 1877
Score = 48.0 bits (109), Expect = 4e-05
Identities = 48/205 (23%), Positives = 94/205 (45%), Gaps = 17/205 (8%)
Frame = +2
Query: 140 NEKAAQEKIVK-QLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQV 316
N K E+++ QLQ +L E Q++ +E L A+ K+ SDL R+LEE ++
Sbjct: 1093 NSKIEDEQVLALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERL 1152
Query: 317 SQLS-----KIKVSLTTQLEDTKRLAD-EEA--RERATLLGKFRNLEHDLDNIREQVEEE 472
+ +I+++ + E K D EEA + AT + + + EQ++
Sbjct: 1153 EEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNL 1212
Query: 473 AEGKADLQRQLSKANAE--------AQLWRSKYESEGVARSEELEEAKRKLQARLAEAEE 628
K L+++ S+ E Q+ ++K E V+R+ LE+ + + +L EA+
Sbjct: 1213 QRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRT--LEDQANEYRVKLEEAQR 1270
Query: 629 TIESLNQKVVALEKTKQRLATEVED 703
++ + L+ L+ ++E+
Sbjct: 1271 SLNDFTTQRAKLQTENGELSRQLEE 1295
Score = 43.2 bits (97), Expect = 0.001
Identities = 48/202 (23%), Positives = 89/202 (44%), Gaps = 13/202 (6%)
Frame = +2
Query: 143 EKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQ 322
E A ++ +++ L + +++ E + L K L ++ L +AE + Q
Sbjct: 850 EMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEERCDQ 909
Query: 323 LSKIKVSLTTQ-------LEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEG 481
L K K+ L + LED E A L K R LE + +++ ++
Sbjct: 910 LIKNKIQLEAKVKEMNERLED-------EEEMNAELTAKKRKLEDECSELKKDID----- 957
Query: 482 KADLQRQLSKANAEAQLWRSKYE--SEGVARSEE----LEEAKRKLQARLAEAEETIESL 643
DL+ L+K E +K + +E +A +E L + K+ LQ +A + +++
Sbjct: 958 --DLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAE 1015
Query: 644 NQKVVALEKTKQRLATEVEDLQ 709
KV L K+K +L +V+DL+
Sbjct: 1016 EDKVNTLSKSKVKLEQQVDDLE 1037
>Z38133-1|CAA86293.1| 1937|Homo sapiens Myosin protein.
Length = 1937
Score = 222 bits (542), Expect = 1e-57
Identities = 107/235 (45%), Positives = 161/235 (68%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
++++GEQ+D L ++K K EK +++ E +DL + + +S K EK+ + L+ Q++E+
Sbjct: 1203 MAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVSEL 1262
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
++K +E R +NDL A + +L E + RQL+E ++ VSQLS+ K + T Q+E+ K
Sbjct: 1263 KTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQL 1322
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEG 559
+EE + + L ++ HD D +REQ EEE EGKA+LQR LSKAN+E WR+KYE++
Sbjct: 1323 EEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDA 1382
Query: 560 VARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
+ R+EELEEAK+KL RL EAEE +E++N K +LEKTKQRL EVEDL L+V+R
Sbjct: 1383 IQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVER 1437
Score = 73.3 bits (172), Expect = 9e-13
Identities = 63/231 (27%), Positives = 106/231 (45%), Gaps = 2/231 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+ D+ + D++N L K + + +V+DL L+ + E+ ++L+ L
Sbjct: 1010 LDDLQAEEDKVNILT----KAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLA 1065
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
Q + LD +K E S+L+ ++E+ ++ QL K L ++E+
Sbjct: 1066 QESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEI 1125
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLS-KANAEAQLWRSKYESE 556
+ E RA + +L +L+ I E++ EEA G Q +L+ K AE Q R E E
Sbjct: 1126 EAERASRAKAEKQRSDLSRELEEISERL-EEAGGATSAQVELNKKREAEFQKLRRDLE-E 1183
Query: 557 GVARSEELEEAKRKLQA-RLAEAEETIESLNQKVVALEKTKQRLATEVEDL 706
+ E + A RK A +AE E I++L + LEK K L E +DL
Sbjct: 1184 ATLQHEAMVAALRKKHADSMAELGEQIDNLQRVKQKLEKEKSELKMETDDL 1234
Score = 64.1 bits (149), Expect = 5e-10
Identities = 50/231 (21%), Positives = 104/231 (45%), Gaps = 1/231 (0%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQ-EKIVKQLQHQLNEVQSKA 211
EQ ++ + KA+ ++ ++ SEV R + + ++ + E+ K+L +L E +
Sbjct: 1348 EQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEHV 1407
Query: 212 DEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEA 391
+ N L+ K++L E DL+ +E + + + L K + + L + K+ +E
Sbjct: 1408 EAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQ 1467
Query: 392 RERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARS 571
E + R+L +L ++ EE + L+R+ E + +EG +
Sbjct: 1468 AELEASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQI-AEGGKQI 1526
Query: 572 EELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
ELE+ K++++ E + +E + E R+ E+ ++ EVDR
Sbjct: 1527 HELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDR 1577
Score = 62.1 bits (144), Expect = 2e-09
Identities = 59/242 (24%), Positives = 112/242 (46%), Gaps = 10/242 (4%)
Frame = +2
Query: 14 RFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLN 193
R V M LD + + A + + + ++N++ L+H + A + + Q L
Sbjct: 1595 RVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQGILK 1654
Query: 194 EVQSKADEANRTLNDLDAAKKKLSI--ENSDLLR-QLEEAESQVSQLSKIKVSLTTQLED 364
E Q D+A R DL K++L+I ++LL+ ++EE + + Q + + +L D
Sbjct: 1655 ETQLHLDDALRGQEDL---KEQLAIVERRANLLQAEIEELWATLEQTERSRKIAEQELLD 1711
Query: 365 TKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRS- 541
+ +L+ + LE+D+ ++ +VEE + + + + KA +A +
Sbjct: 1712 ASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEE 1771
Query: 542 -KYESEGVARSE----ELEEAKRKLQARLAEAEE-TIESLNQKVVALEKTKQRLATEVED 703
K E + A E LE+ + LQ RL EAE+ ++ +++ LE + L EVE+
Sbjct: 1772 LKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVEN 1831
Query: 704 LQ 709
Q
Sbjct: 1832 EQ 1833
Score = 60.9 bits (141), Expect = 5e-09
Identities = 48/214 (22%), Positives = 108/214 (50%), Gaps = 10/214 (4%)
Frame = +2
Query: 68 KAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDA 247
+A+K AQ E + ++ ++ + A+ EK ++LQ+++ ++ + +N LD
Sbjct: 1391 EAKKKLAQRLQEAEE---HVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDK 1447
Query: 248 AKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRN 427
++ S+ ++ EE ++++ K SL+T+L K + +E + TL + +N
Sbjct: 1448 KQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRRENKN 1507
Query: 428 LEHDLDNIREQVEEEAEGKADLQ---RQLSKANAEAQLWRSKYES-----EG-VARSE-E 577
L+ ++ ++ EQ+ E + +L+ +Q+ + E Q + E+ EG + R + E
Sbjct: 1508 LQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLE 1567
Query: 578 LEEAKRKLQARLAEAEETIESLNQKVVALEKTKQ 679
L + K ++ ++AE +E I+ L + + +T Q
Sbjct: 1568 LNQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQ 1601
Score = 60.5 bits (140), Expect = 7e-09
Identities = 48/235 (20%), Positives = 106/235 (45%), Gaps = 1/235 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
V D+ +++ N A +K + + +++ + + E A +K + L +L +V
Sbjct: 1428 VEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKV 1487
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
++ +E+ L L K L E SDL Q+ E Q+ +L KIK + + + +
Sbjct: 1488 KNVYEESLDQLETLRRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAAL 1547
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAE-AQLWRSKYESE 556
+E GK ++ +L+ ++ +V+ + K + QL + + + +S ++E
Sbjct: 1548 EEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQSTLDAE 1607
Query: 557 GVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
+R++ L K+K++ L E E + N+ + + +++ QL +D
Sbjct: 1608 IRSRNDAL-RVKKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQGILKETQLHLD 1661
Score = 59.3 bits (137), Expect = 2e-08
Identities = 51/236 (21%), Positives = 109/236 (46%), Gaps = 2/236 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+ ++ QL++ K K + + LR + KA ++ + + ++ +
Sbjct: 1315 IEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQW 1374
Query: 200 QSKAD-EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRL 376
++K + +A + +L+ AKKKL+ + +E ++ + L K K L ++ED
Sbjct: 1375 RTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLD 1434
Query: 377 ADEEARERATLLGKFRNLEHDLDNIREQVEE-EAEGKADLQRQLSKANAEAQLWRSKYES 553
+ A L K RN + L +++ EE +AE +A Q++ + E ++ YE
Sbjct: 1435 VERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEAS-QKESRSLSTELFKVKNVYE- 1492
Query: 554 EGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
E + + E L + LQ +++ E I +++ LEK K+++ E ++Q ++
Sbjct: 1493 ESLDQLETLRRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALE 1548
Score = 52.8 bits (121), Expect = 1e-06
Identities = 48/226 (21%), Positives = 98/226 (43%), Gaps = 2/226 (0%)
Frame = +2
Query: 26 DMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNE-KAAQEKIVKQLQHQLNEVQ 202
D E++ L+ + + ++V+ L++ ++ + E + A+EK K + +
Sbjct: 1711 DASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAE 1770
Query: 203 SKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVS-LTTQLEDTKRLA 379
E + + + L+ KK L DL +L+EAE + K ++ L ++ + +
Sbjct: 1771 ELKKEQDTSAH-LERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEV 1829
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEG 559
+ E + A + R E + + Q EE+ + LQ + K A+ + ++ + E
Sbjct: 1830 ENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEAE 1889
Query: 560 VARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEV 697
+ L + RKLQ L EAEE +V L + + T++
Sbjct: 1890 EQSNANLSKF-RKLQHELEEAEERAHIAESQVNKLRVKSREVHTKI 1934
Score = 50.0 bits (114), Expect = 9e-06
Identities = 41/178 (23%), Positives = 80/178 (44%), Gaps = 2/178 (1%)
Frame = +2
Query: 29 MGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSN-EKAAQEKIVKQLQHQLNEVQS 205
M E+L + A E+ + V DL+ LD +K +++L+ ++ E++
Sbjct: 1768 MAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEG 1827
Query: 206 KADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADE 385
+ + + + +K +L Q EE V +L + L +++ KR A+E
Sbjct: 1828 EVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEE 1887
Query: 386 EARERATLLGKFRNLEHDLDNIREQVEEEAEGKADL-QRQLSKANAEAQLWRSKYESE 556
+ L KFR L+H+L EEAE +A + + Q++K +++ +K +E
Sbjct: 1888 AEEQSNANLSKFRKLQHEL--------EEAEERAHIAESQVNKLRVKSREVHTKISAE 1937
Score = 46.8 bits (106), Expect = 9e-05
Identities = 53/217 (24%), Positives = 100/217 (46%), Gaps = 10/217 (4%)
Frame = +2
Query: 104 VNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLND-----LDAAKKK--L 262
++D G + L + A E+ LQ ++ E+ + ++ R+ LDA+++ L
Sbjct: 1660 LDDALRGQEDLKEQLAIVERRANLLQAEIEELWATLEQTERSRKIAEQELLDASERVQLL 1719
Query: 263 SIENSDLLRQLEEAESQVSQL-SKIK--VSLTTQLEDTKRLADEEARERATLLGKFRNLE 433
+N+ L+ ++ E+ VSQL S+++ + + E+ + A +A A L K ++
Sbjct: 1720 HTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTS 1779
Query: 434 HDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARL 613
L+ +++ +E+ + DLQ +L +A A K + AR ELE Q R
Sbjct: 1780 AHLERMKKNLEQTVK---DLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRN 1836
Query: 614 AEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
AEA + + ++V L + V LQ VD+
Sbjct: 1837 AEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDK 1873
>M36769-1|AAC17185.1| 1937|Homo sapiens perinatal myosin heavy chain
protein.
Length = 1937
Score = 219 bits (535), Expect = 9e-57
Identities = 106/235 (45%), Positives = 160/235 (68%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
++++GEQ+D L ++K K EK +++ E +DL + + +S K EK+ + L+ Q++ +
Sbjct: 1203 MAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGHLEKMCRSLEDQVSGL 1262
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
++K +E R +NDL A + +L E + RQL+E ++ VSQLS+ K + T Q+E+ K
Sbjct: 1263 KTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEQDALVSQLSRSKQASTQQIEELKHQL 1322
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEG 559
+EE + + L ++ HD D +REQ EEE EGKA+LQR LSKAN+E WR+KYE++
Sbjct: 1323 EEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDA 1382
Query: 560 VARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
+ R+EELEEAK+KL RL EAEE +E++N K +LEKTKQRL EVEDL L+V+R
Sbjct: 1383 IQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVER 1437
Score = 73.3 bits (172), Expect = 9e-13
Identities = 63/231 (27%), Positives = 106/231 (45%), Gaps = 2/231 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+ D+ + D++N L K + + +V+DL L+ + E+ ++L+ L
Sbjct: 1010 LDDLQAEEDKVNILT----KAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLA 1065
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
Q + LD +K E S+L+ ++E+ ++ QL K L ++E+
Sbjct: 1066 QESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEI 1125
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLS-KANAEAQLWRSKYESE 556
+ E RA + +L +L+ I E++ EEA G Q +L+ K AE Q R E E
Sbjct: 1126 EAERASRAKAEKQRSDLSRELEEISERL-EEAGGATSAQVELNKKREAEFQKLRRDLE-E 1183
Query: 557 GVARSEELEEAKRKLQA-RLAEAEETIESLNQKVVALEKTKQRLATEVEDL 706
+ E + A RK A +AE E I++L + LEK K L E +DL
Sbjct: 1184 ATLQHEAMVAALRKKHADSMAELGEQIDNLQRVKQKLEKEKSELKMETDDL 1234
Score = 62.9 bits (146), Expect = 1e-09
Identities = 50/231 (21%), Positives = 103/231 (44%), Gaps = 1/231 (0%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQ-EKIVKQLQHQLNEVQSKA 211
EQ ++ + KA+ ++ ++ SEV R + + ++ + E+ K+L +L E +
Sbjct: 1348 EQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEHV 1407
Query: 212 DEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEA 391
+ N L+ K++L E DL+ +E + + + L K + + L + K+ +E
Sbjct: 1408 EAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQ 1467
Query: 392 RERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARS 571
E + R+L +L ++ EE + L+R E + +EG +
Sbjct: 1468 AELEASQKESRSLSTELFKVKNVYEESLDQLETLRRAHKNLQQEISDLTEQI-AEGGKQI 1526
Query: 572 EELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
ELE+ K++++ E + +E + E R+ E+ ++ EVDR
Sbjct: 1527 HELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDR 1577
Score = 62.1 bits (144), Expect = 2e-09
Identities = 49/235 (20%), Positives = 107/235 (45%), Gaps = 1/235 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
V D+ +++ N A +K + + +++ + + E A +K + L +L +V
Sbjct: 1428 VEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKV 1487
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
++ +E+ L L A K L E SDL Q+ E Q+ +L KIK + + + +
Sbjct: 1488 KNVYEESLDQLETLRRAHKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAAL 1547
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAE-AQLWRSKYESE 556
+E GK ++ +L+ ++ +V+ + K + QL + + + +S ++E
Sbjct: 1548 EEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQSTLDAE 1607
Query: 557 GVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
+R++ L K+K++ L E E + N+ + + +++ QL +D
Sbjct: 1608 IRSRNDAL-RVKKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQGILKETQLHLD 1661
Score = 62.1 bits (144), Expect = 2e-09
Identities = 59/242 (24%), Positives = 112/242 (46%), Gaps = 10/242 (4%)
Frame = +2
Query: 14 RFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLN 193
R V M LD + + A + + + ++N++ L+H + A + + Q L
Sbjct: 1595 RVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQGILK 1654
Query: 194 EVQSKADEANRTLNDLDAAKKKLSI--ENSDLLR-QLEEAESQVSQLSKIKVSLTTQLED 364
E Q D+A R DL K++L+I ++LL+ ++EE + + Q + + +L D
Sbjct: 1655 ETQLHLDDALRGQEDL---KEQLAIVERRANLLQAEIEELWATLEQTERSRKIAEQELLD 1711
Query: 365 TKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRS- 541
+ +L+ + LE+D+ ++ +VEE + + + + KA +A +
Sbjct: 1712 ASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEE 1771
Query: 542 -KYESEGVARSE----ELEEAKRKLQARLAEAEE-TIESLNQKVVALEKTKQRLATEVED 703
K E + A E LE+ + LQ RL EAE+ ++ +++ LE + L EVE+
Sbjct: 1772 LKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVEN 1831
Query: 704 LQ 709
Q
Sbjct: 1832 EQ 1833
Score = 60.9 bits (141), Expect = 5e-09
Identities = 52/236 (22%), Positives = 110/236 (46%), Gaps = 2/236 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+ ++ QL++ K K + + LR + KA ++ + + ++ +
Sbjct: 1315 IEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQW 1374
Query: 200 QSKAD-EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRL 376
++K + +A + +L+ AKKKL+ + +E ++ + L K K L ++ED
Sbjct: 1375 RTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLD 1434
Query: 377 ADEEARERATLLGKFRNLEHDLDNIREQVEE-EAEGKADLQRQLSKANAEAQLWRSKYES 553
+ A L K RN + L +++ EE +AE +A Q++ + E ++ YE
Sbjct: 1435 VERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEAS-QKESRSLSTELFKVKNVYE- 1492
Query: 554 EGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
E + + E L A + LQ +++ E I +++ LEK K+++ E ++Q ++
Sbjct: 1493 ESLDQLETLRRAHKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALE 1548
Score = 60.9 bits (141), Expect = 5e-09
Identities = 48/214 (22%), Positives = 107/214 (50%), Gaps = 10/214 (4%)
Frame = +2
Query: 68 KAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDA 247
+A+K AQ E + ++ ++ + A+ EK ++LQ+++ ++ + +N LD
Sbjct: 1391 EAKKKLAQRLQEAEE---HVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDK 1447
Query: 248 AKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRN 427
++ S+ ++ EE ++++ K SL+T+L K + +E + TL +N
Sbjct: 1448 KQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRRAHKN 1507
Query: 428 LEHDLDNIREQVEEEAEGKADLQ---RQLSKANAEAQLWRSKYES-----EG-VARSE-E 577
L+ ++ ++ EQ+ E + +L+ +Q+ + E Q + E+ EG + R + E
Sbjct: 1508 LQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLE 1567
Query: 578 LEEAKRKLQARLAEAEETIESLNQKVVALEKTKQ 679
L + K ++ ++AE +E I+ L + + +T Q
Sbjct: 1568 LNQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQ 1601
Score = 52.8 bits (121), Expect = 1e-06
Identities = 42/178 (23%), Positives = 81/178 (45%), Gaps = 2/178 (1%)
Frame = +2
Query: 29 MGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSN-EKAAQEKIVKQLQHQLNEVQS 205
M E+L + A E+ + V DL+ LD +K +++L+ ++ E++
Sbjct: 1768 MAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEG 1827
Query: 206 KADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADE 385
+ + + + +K +L Q EE V +L + L +++ KR A+E
Sbjct: 1828 EVENEQKRNAEAVKGLRKHDRRVKELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEE 1887
Query: 386 EARERATLLGKFRNLEHDLDNIREQVEEEAEGKADL-QRQLSKANAEAQLWRSKYESE 556
+ L KFR L+H+L EEAE +AD+ + Q++K +++ +K +E
Sbjct: 1888 AEEQSNANLSKFRKLQHEL--------EEAEERADIAESQVNKLRVKSREVHTKISAE 1937
Score = 52.4 bits (120), Expect = 2e-06
Identities = 47/226 (20%), Positives = 99/226 (43%), Gaps = 2/226 (0%)
Frame = +2
Query: 26 DMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNE-KAAQEKIVKQLQHQLNEVQ 202
D E++ L+ + + ++V+ L++ ++ + E + A+EK K + +
Sbjct: 1711 DASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAE 1770
Query: 203 SKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVS-LTTQLEDTKRLA 379
E + + + L+ KK L DL +L+EAE + K ++ L ++ + +
Sbjct: 1771 ELKKEQDTSAH-LERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEV 1829
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEG 559
+ E + A + R + + + Q EE+ + LQ + K A+ + ++ + E
Sbjct: 1830 ENEQKRNAEAVKGLRKHDRRVKELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEAE 1889
Query: 560 VARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEV 697
+ L + RKLQ L EAEE + +V L + + T++
Sbjct: 1890 EQSNANLSKF-RKLQHELEEAEERADIAESQVNKLRVKSREVHTKI 1934
Score = 47.2 bits (107), Expect = 7e-05
Identities = 53/217 (24%), Positives = 101/217 (46%), Gaps = 10/217 (4%)
Frame = +2
Query: 104 VNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLND-----LDAAKKK--L 262
++D G + L + A E+ LQ ++ E+ + ++ R+ LDA+++ L
Sbjct: 1660 LDDALRGQEDLKEQLAIVERRANLLQAEIEELWATLEQTERSRKIAEQELLDASERVQLL 1719
Query: 263 SIENSDLLRQLEEAESQVSQL-SKIK--VSLTTQLEDTKRLADEEARERATLLGKFRNLE 433
+N+ L+ ++ E+ VSQL S+++ + + E+ + A +A A L K ++
Sbjct: 1720 HTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTS 1779
Query: 434 HDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARL 613
L+ +++ +E+ + DLQ +L +A A K + AR ELE Q R
Sbjct: 1780 AHLERMKKNLEQTVK---DLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRN 1836
Query: 614 AEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
AEA + + +++V L + V LQ VD+
Sbjct: 1837 AEAVKGLRKHDRRVKELTYQTEEDRKNVLRLQDLVDK 1873
>X03740-1|CAA27380.1| 876|Homo sapiens protein ( Human skeletal
mRNA for myosin heavy chain light meromyosin region. ).
Length = 876
Score = 218 bits (532), Expect = 2e-56
Identities = 103/235 (43%), Positives = 162/235 (68%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
V+++GEQ+D L ++K K EK +++ E++DL + ++ +S K EK+ + L+ QL+E+
Sbjct: 141 VAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEI 200
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
++K +E R +NDL A + +L + RQL+E ++ +QLS+ K + T Q+E+ KR
Sbjct: 201 KTKEEEQQRLINDLTAQRARLQQNQVEYSRQLDEKDTLETQLSRGKQAFTQQIEELKRQL 260
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEG 559
+EE + ++ L ++ HD D +REQ EEE E KA+LQR +SKAN+E WR+KYE++
Sbjct: 261 EEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDA 320
Query: 560 VARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
+ R+EELEEAK+KL RL +AEE +E++N K +LEKTKQRL EVEDL ++V+R
Sbjct: 321 IQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVER 375
Score = 71.3 bits (167), Expect = 4e-12
Identities = 54/236 (22%), Positives = 118/236 (50%), Gaps = 2/236 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+SD+ EQ+ + K + EK + Q E ++L+A L+ +E + ++Q ++N+V
Sbjct: 450 ISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLEVNQV 509
Query: 200 QSKAD-EANRTLNDLDAAKKK-LSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKR 373
+S+ D + ++D K+ + IE S E S+ + ++K + L + +
Sbjct: 510 KSEVDRKIAEKDEEIDQMKRNHIRIEESMQSTLNAEIRSR-NDAIRLKKKMEGDLNEMEI 568
Query: 374 LADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYES 553
+ R A L ++N + L + + +++ + DL+ QL+ A L +++ E
Sbjct: 569 QLNHANRMAAEDLRNYQNTQAILKDTQLHLDDALRSQEDLKEQLAMVERRANLLQAEIE- 627
Query: 554 EGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
E A E+ E +++ + L +A E ++ L+ + +L TK++L T++ +Q E++
Sbjct: 628 ELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEME 683
Score = 66.9 bits (156), Expect = 8e-11
Identities = 51/231 (22%), Positives = 104/231 (45%), Gaps = 1/231 (0%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQ-EKIVKQLQHQLNEVQSKA 211
EQ ++ + KA+ ++ ++ SEV R + + ++ + E+ K+L +L + +
Sbjct: 286 EQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHV 345
Query: 212 DEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEA 391
+ N L+ K++L E DL+ +E + + L K + + L + K+ +E
Sbjct: 346 EAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQTNFDKILAEWKQKCEETH 405
Query: 392 RERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARS 571
+ + R+L +L I+ EE + L+R+ E + +EG R
Sbjct: 406 AVLESFQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQI-AEGGKRI 464
Query: 572 EELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
ELE+ K++++ +E + +E + E R+ EV ++ EVDR
Sbjct: 465 HELEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLEVNQVKSEVDR 515
Score = 61.3 bits (142), Expect = 4e-09
Identities = 52/237 (21%), Positives = 110/237 (46%), Gaps = 3/237 (1%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFS--EVNDLRAGLDHLSNEKAAQEKIVKQLQHQLN 193
+ ++ QL++ ++KAK+ A S + + LR + KA ++ + + ++
Sbjct: 253 IEELKRQLEE--EIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQRAMSKANSEVA 310
Query: 194 EVQSKAD-EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTK 370
+ ++K + +A + +L+ AKKKL+ D +E ++ + L K K L ++ED
Sbjct: 311 QWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLM 370
Query: 371 RLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYE 550
+ A L K N + L +++ EE Q++ + E ++ YE
Sbjct: 371 IDVERTNAACAALDKKQTNFDKILAEWKQKCEETHAVLESFQKESRSLSTELFKIKNAYE 430
Query: 551 SEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
E + + E L+ + LQ +++ E I +++ LEK K+++ E +LQ ++
Sbjct: 431 -ESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAALE 486
Score = 59.3 bits (137), Expect = 2e-08
Identities = 46/170 (27%), Positives = 75/170 (44%), Gaps = 1/170 (0%)
Frame = +2
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
Q A + LD KK E S L ++E+ ++ QL K L ++E+ +
Sbjct: 4 QESAMDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEI 63
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLS-KANAEAQLWRSKYESE 556
+ E RA +L +L+ I E++ EEA G Q +++ K AE Q R E
Sbjct: 64 EAERTSRAKAEKLRSDLSRELEEISERL-EEAVGATSTQIEMNKKREAEFQKMRRDLEEA 122
Query: 557 GVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDL 706
+ ++K +AE E I++L + LEK K + E++DL
Sbjct: 123 TLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDL 172
Score = 57.6 bits (133), Expect = 5e-08
Identities = 42/212 (19%), Positives = 104/212 (49%), Gaps = 10/212 (4%)
Frame = +2
Query: 74 EKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAK 253
E+ + + + D ++ ++ + A+ EK ++LQ+++ ++ + N LD +
Sbjct: 328 EEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQ 387
Query: 254 KKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLE 433
++ ++ EE + + K SL+T+L K +E + TL + +NL+
Sbjct: 388 TNFDKILAEWKQKCEETHAVLESFQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQ 447
Query: 434 HDLDNIREQVEEEAEGKADLQ---RQLSKANAEAQLWRSKYES-----EG-VARSE-ELE 583
++ ++ EQ+ E + +L+ +Q+ + +E Q + E+ EG + R + E+
Sbjct: 448 QEISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLEVN 507
Query: 584 EAKRKLQARLAEAEETIESLNQKVVALEKTKQ 679
+ K ++ ++AE +E I+ + + + +E++ Q
Sbjct: 508 QVKSEVDRKIAEKDEEIDQMKRNHIRIEESMQ 539
Score = 55.2 bits (127), Expect = 3e-07
Identities = 45/237 (18%), Positives = 102/237 (43%), Gaps = 1/237 (0%)
Frame = +2
Query: 14 RFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLN 193
R M L+ + + A + + + ++N++ L+H + A + + Q L
Sbjct: 533 RIEESMQSTLNAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEDLRNYQNTQAILK 592
Query: 194 EVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKR 373
+ Q D+A R+ DL + + L ++EE + + Q + + +L D
Sbjct: 593 DTQLHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASE 652
Query: 374 LADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYES 553
+ +L+ + LE D+ I+ ++E+ + + + + KA +A + + +
Sbjct: 653 RVQLLHTQNTSLINTKKKLETDISQIQGEMEDIIKEARNAEEKAKKAITDAAMMAEELKK 712
Query: 554 EGVARSEELEEAKRKLQARLAEAEETIESLNQKVV-ALEKTKQRLATEVEDLQLEVD 721
E S LE K+ L+ + + + ++ Q + +K Q+L +V +L+ EV+
Sbjct: 713 E-QDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEAKVRELEGEVE 768
Score = 50.4 bits (115), Expect = 7e-06
Identities = 41/178 (23%), Positives = 81/178 (45%), Gaps = 2/178 (1%)
Frame = +2
Query: 29 MGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSN-EKAAQEKIVKQLQHQLNEVQS 205
M E+L + A E+ + V DL+ LD +K +++L+ ++ E++
Sbjct: 706 MAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEAKVRELEG 765
Query: 206 KADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADE 385
+ + + + K + +L Q EE + +L + L +++ KR A+E
Sbjct: 766 EVESEQKRNVEAVKGLHKHERKVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEE 825
Query: 386 EARERATLLGKFRNLEHDLDNIREQVEEEAEGKADL-QRQLSKANAEAQLWRSKYESE 556
+ L KFR ++H+L EEAE +AD+ + Q++K +++ +K SE
Sbjct: 826 AEEQSNVNLSKFRRIQHEL--------EEAEERADIAESQVNKLRVKSREVHTKIISE 875
Score = 48.4 bits (110), Expect = 3e-05
Identities = 38/198 (19%), Positives = 90/198 (45%), Gaps = 3/198 (1%)
Frame = +2
Query: 134 LSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQ 313
+ N+K ++ +K+ + +++ +QSK ++ L K+L +L ++E +
Sbjct: 10 IENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERTS 69
Query: 314 VSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADL 493
++ K++ L+ +LE+ +E +T + + E + +R +EE A L
Sbjct: 70 RAKAEKLRSDLSRELEEISERLEEAVGATSTQIEMNKKREAEFQKMRRDLEE-----ATL 124
Query: 494 QRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKT 673
Q + + A + + +E + + L+ K+KL+ +E + I+ L + + K
Sbjct: 125 QHEATAATLRKK--HADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKA 182
Query: 674 K---QRLATEVEDLQLEV 718
K +++ +ED E+
Sbjct: 183 KGNLEKMCRALEDQLSEI 200
Score = 45.6 bits (103), Expect = 2e-04
Identities = 60/250 (24%), Positives = 105/250 (42%), Gaps = 17/250 (6%)
Frame = +2
Query: 26 DMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQL---QHQLNE 196
D+ E QLN A + Y + L+ HL + +QE + +QL + + N
Sbjct: 562 DLNEMEIQLNHANRMAAEDLRNYQNTQAILKDTQLHLDDALRSQEDLKEQLAMVERRANL 621
Query: 197 VQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTT-------Q 355
+Q++ +E TL + ++K E D +++ +Q + L K L T +
Sbjct: 622 LQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGE 681
Query: 356 LEDT---KRLADEEARERAT---LLGKFRNLEHDLDNIREQVEEEAEGKA-DLQRQLSKA 514
+ED R A+E+A++ T ++ + E D E++++ E DLQ +L +A
Sbjct: 682 MEDIIKEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEA 741
Query: 515 NAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATE 694
A K + A+ ELE Q R EA + + +KV L +
Sbjct: 742 EQLALKGGKKQIQKLEAKVRELEGEVESEQKRNVEAVKGLHKHERKVKELTYQTEEDRKN 801
Query: 695 VEDLQLEVDR 724
+ LQ VD+
Sbjct: 802 ILRLQDLVDK 811
Score = 44.4 bits (100), Expect = 5e-04
Identities = 46/224 (20%), Positives = 97/224 (43%), Gaps = 8/224 (3%)
Frame = +2
Query: 74 EKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAK 253
E + Q ++ + L ++ ++ + QLQ ++ E+Q++ +E + ++
Sbjct: 11 ENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERTSR 70
Query: 254 KKLSIENSDLLRQLEEAESQVSQL-----SKIKVSLTTQLEDTKRLAD-EEA--RERATL 409
K SDL R+LEE ++ + ++I+++ + E K D EEA + AT
Sbjct: 71 AKAEKLRSDLSRELEEISERLEEAVGATSTQIEMNKKREAEFQKMRRDLEEATLQHEATA 130
Query: 410 LGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEA 589
+ + + EQ++ K L+++ S+ E S E+ A+ LE+
Sbjct: 131 ATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKG-NLEKM 189
Query: 590 KRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
R L+ +L+E + E + + L + RL + ++D
Sbjct: 190 CRALEDQLSEIKTKEEEQQRLINDLTAQRARLQQNQVEYSRQLD 233
>AF111782-1|AAD29948.1| 1938|Homo sapiens myosin heavy chain protein.
Length = 1938
Score = 215 bits (524), Expect = 2e-55
Identities = 101/235 (42%), Positives = 161/235 (68%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
V+++GEQ+D L ++K K EK +++ E++D+ + ++ LS K+ E+ + ++ Q +E+
Sbjct: 1204 VAELGEQIDNLQRVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQFSEI 1263
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
++K ++ + ++DL+ K +L +N +L ++EE ES +SQL+K K +LT QLE+ KR
Sbjct: 1264 KAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLEELKRQM 1323
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEG 559
+EE + + + ++ HD D +REQ EEE E KA+LQR LSKAN+E W++KYE++
Sbjct: 1324 EEETKAKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWKTKYETDA 1383
Query: 560 VARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
+ R+EELEEAK+KL RL EAEE E+ N K +LEKTKQRL EVEDL +++R
Sbjct: 1384 IQRTEELEEAKKKLAQRLQEAEEKTETANSKCASLEKTKQRLQGEVEDLMRDLER 1438
Score = 71.3 bits (167), Expect = 4e-12
Identities = 59/238 (24%), Positives = 106/238 (44%), Gaps = 9/238 (3%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKA- 211
+QL++L + + K + + R D L + +++ +LQ L++ S+
Sbjct: 1314 QQLEELKRQMEEETKAKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVA 1373
Query: 212 --------DEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDT 367
D RT +L+ AKKKL+ + + E A S+ + L K K L ++ED
Sbjct: 1374 QWKTKYETDAIQRT-EELEEAKKKLAQRLQEAEEKTETANSKCASLEKTKQRLQGEVEDL 1432
Query: 368 KRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKY 547
R + ATL K RN + L +++++E Q++ + E R+ Y
Sbjct: 1433 MRDLERSHTACATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAY 1492
Query: 548 ESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
E E V + E L + LQ +++ E I + + EKTK+ + E DLQ+ ++
Sbjct: 1493 E-EVVDQLETLRRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALE 1549
Score = 64.9 bits (151), Expect = 3e-10
Identities = 52/216 (24%), Positives = 98/216 (45%), Gaps = 1/216 (0%)
Frame = +2
Query: 77 KXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKK 256
K A+ + +DL L+ +A E+ ++L+ L Q + ++ K
Sbjct: 1026 KINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGDLKMSQESIMDLENEKQQIEEKLK 1085
Query: 257 KLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEH 436
K E S L ++++ + Q K L ++E+ + + E RA + + +L
Sbjct: 1086 KKEFELSQLQARIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIEKQRSDLAR 1145
Query: 437 DLDNIREQVEEEAEGKADLQRQLSKAN-AEAQLWRSKYESEGVARSEELEEAKRKLQARL 613
+L+ I E++EE A G Q +++K AE Q R E E + E RK QA
Sbjct: 1146 ELEEISERLEE-ASGATSAQIEMNKKREAEFQKMRRDLE-EATLQHEATAATLRKKQA-- 1201
Query: 614 AEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
+++ L +++ L++ KQ+L E +L++E+D
Sbjct: 1202 ----DSVAELGEQIDNLQRVKQKLEKEKSELKMEID 1233
Score = 64.9 bits (151), Expect = 3e-10
Identities = 48/228 (21%), Positives = 102/228 (44%), Gaps = 1/228 (0%)
Frame = +2
Query: 41 LDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEA 220
LD + + A + + + ++N++ L H + + A ++ ++ +Q QL + Q D+A
Sbjct: 1605 LDAEIRSRNDALRLKKKMEGDLNEMEIQLGHSNRQMAETQRHLRTVQGQLKDSQLHLDDA 1664
Query: 221 NRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARER 400
R+ DL + N LL +LEE + + Q + + +L D +
Sbjct: 1665 LRSNEDLKEQLAIVERRNGLLLEELEEMKVALEQTERTRRLSEQELLDASDRVQLLHSQN 1724
Query: 401 ATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEEL 580
+L+ + LE D+ + +VE + + + + KA +A + + + E S L
Sbjct: 1725 TSLINTKKKLEADIAQCQAEVENSIQESRNAEEKAKKAITDAAMMAEELKKE-QDTSAHL 1783
Query: 581 EEAKRKLQARLAEAEETIESLNQKVV-ALEKTKQRLATEVEDLQLEVD 721
E K+ L+ + + + ++ Q + +K Q+L V +L+ E+D
Sbjct: 1784 ERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLENRVRELENELD 1831
Score = 54.4 bits (125), Expect = 4e-07
Identities = 46/244 (18%), Positives = 105/244 (43%), Gaps = 7/244 (2%)
Frame = +2
Query: 14 RFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLN 193
+ +++ ++LD+ A+K +E+ +R + + ++ + K LQ +++
Sbjct: 1455 KVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETLRRENKNLQEEIS 1514
Query: 194 EVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKR 373
++ + E + L + + KK + E SDL LEE E + + + +L K
Sbjct: 1515 DLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKILRVQLELSQVKS 1574
Query: 374 LADEEARERATLLGKF-RNLEHDLDNIREQVEEEAEGKADLQRQLSKANA-----EAQLW 535
D + E+ + + RN + + ++ ++ E + D R K E QL
Sbjct: 1575 ELDRKVIEKDEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALRLKKKMEGDLNEMEIQLG 1634
Query: 536 RSKYESEGVARSEELEEAKRK-LQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQL 712
S + R + + K Q L +A + E L +++ +E+ L E+E++++
Sbjct: 1635 HSNRQMAETQRHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIVERRNGLLLEELEEMKV 1694
Query: 713 EVDR 724
+++
Sbjct: 1695 ALEQ 1698
Score = 54.0 bits (124), Expect = 6e-07
Identities = 49/221 (22%), Positives = 106/221 (47%), Gaps = 3/221 (1%)
Frame = +2
Query: 68 KAEKXRAQYFSEVNDLRAGLDHLSNEKAAQ-EKIVKQLQHQLNEVQSKADEANRTLNDLD 244
+A+K AQ E + +N K A EK ++LQ ++ ++ + ++ LD
Sbjct: 1392 EAKKKLAQRLQEAEEKT----ETANSKCASLEKTKQRLQGEVEDLMRDLERSHTACATLD 1447
Query: 245 AAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFR 424
++ ++ ++L+E+++++ K SL+T+L + +E + TL + +
Sbjct: 1448 KKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETLRRENK 1507
Query: 425 NLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAK-RKL 601
NL+ ++ ++ EQ+ E GK + + +K E + + E V S E EE+K ++
Sbjct: 1508 NLQEEISDLTEQIAE--TGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKILRV 1565
Query: 602 QARLAEAEETIE-SLNQKVVALEKTKQRLATEVEDLQLEVD 721
Q L++ + ++ + +K +E+ K+ E LQ +D
Sbjct: 1566 QLELSQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQSVLD 1606
Score = 52.8 bits (121), Expect = 1e-06
Identities = 54/241 (22%), Positives = 110/241 (45%), Gaps = 7/241 (2%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
V D+ L++ + A +K + + + + + LD E A +K + L +L ++
Sbjct: 1429 VEDLMRDLERSHTACATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKM 1488
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQ-------LEEAESQVSQLSKIKVSLTTQL 358
++ +E L L K L E SDL Q L+EAE + + K L L
Sbjct: 1489 RNAYEEVVDQLETLRRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVAL 1548
Query: 359 EDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWR 538
E+ + + E + + + ++ +LD + +EE E L+R +A A+ +
Sbjct: 1549 EEVEGSLEHEESKILRVQLELSQVKSELDRKVIEKDEEIE---QLKRNSQRA---AEALQ 1602
Query: 539 SKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEV 718
S ++E +R++ L K+K++ L E E + N+++ ++ + + +++D QL +
Sbjct: 1603 SVLDAEIRSRNDAL-RLKKKMEGDLNEMEIQLGHSNRQMAETQRHLRTVQGQLKDSQLHL 1661
Query: 719 D 721
D
Sbjct: 1662 D 1662
Score = 50.4 bits (115), Expect = 7e-06
Identities = 43/195 (22%), Positives = 85/195 (43%), Gaps = 6/195 (3%)
Frame = +2
Query: 143 EKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQ 322
E A ++ ++ + +L +++ E + L K L ++ L +AE +
Sbjct: 852 EMATMKEDFERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSETENLMDAEERCEG 911
Query: 323 LSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQ 502
L K K+ L ++++ +EE + L+ K RNLE +++ ++ DL+
Sbjct: 912 LIKSKILLEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDID-------DLELT 964
Query: 503 LSKANAEAQLWRSKYE--SEGVARSEE----LEEAKRKLQARLAEAEETIESLNQKVVAL 664
L+K E +K + SE + EE L + K+ LQ + + ++ KV L
Sbjct: 965 LTKVEKEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVEEDKVNGL 1024
Query: 665 EKTKQRLATEVEDLQ 709
K +L + +DL+
Sbjct: 1025 IKINAKLEQQTDDLE 1039
Score = 43.2 bits (97), Expect = 0.001
Identities = 56/247 (22%), Positives = 114/247 (46%), Gaps = 14/247 (5%)
Frame = +2
Query: 23 SDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQ-EKIVKQLQHQLNEV 199
SD+ L+++ E + E++ +++ LD EK + E++ + Q +
Sbjct: 1542 SDLQVALEEVEGSLEHEESKILRVQLELSQVKSELDRKVIEKDEEIEQLKRNSQRAAEAL 1601
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLL-------RQLEEAESQVSQLSKIKVSLTTQL 358
QS D R+ ND KKK+ + +++ RQ+ E + + + L
Sbjct: 1602 QSVLDAEIRSRNDALRLKKKMEGDLNEMEIQLGHSNRQMAETQRHLRTVQGQLKDSQLHL 1661
Query: 359 EDTKRLADEEARERATLLGKFRN--LEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQL 532
+D R ++E+ +E+ ++ + RN L +L+ ++ +E+ + +++L A+ QL
Sbjct: 1662 DDALR-SNEDLKEQLAIVER-RNGLLLEELEEMKVALEQTERTRRLSEQELLDASDRVQL 1719
Query: 533 WRSKYESEGVARSEELEEAKRKLQARLAEAEETIE-SLNQKVVALEKTKQRL---ATEVE 700
S+ S L K+KL+A +A+ + +E S+ + A EK K+ + A E
Sbjct: 1720 LHSQNTS--------LINTKKKLEADIAQCQAEVENSIQESRNAEEKAKKAITDAAMMAE 1771
Query: 701 DLQLEVD 721
+L+ E D
Sbjct: 1772 ELKKEQD 1778
Score = 37.5 bits (83), Expect = 0.054
Identities = 56/252 (22%), Positives = 114/252 (45%), Gaps = 17/252 (6%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHL--SNEKAAQEKIVKQ-----L 178
+++M QL N+ A+ ++ ++ D + LD SNE ++ + + L
Sbjct: 1626 LNEMEIQLGHSNRQMAETQRHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIVERRNGLL 1685
Query: 179 QHQLNEVQSKADEANRT--LND---LDAAKKK--LSIENSDLLRQLEEAESQVSQL-SKI 334
+L E++ ++ RT L++ LDA+ + L +N+ L+ ++ E+ ++Q +++
Sbjct: 1686 LEELEEMKVALEQTERTRRLSEQELLDASDRVQLLHSQNTSLINTKKKLEADIAQCQAEV 1745
Query: 335 KVSL--TTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLS 508
+ S+ + E+ + A +A A L K ++ L+ +++ +E+ + DLQ +L
Sbjct: 1746 ENSIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVK---DLQHRLD 1802
Query: 509 KANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLA 688
+A A K + R ELE Q R AEA + +KV + +
Sbjct: 1803 EAEQLALKGGKKQIQKLENRVRELENELDVEQKRGAEALKGAHKYERKVKEMTYQAEEDR 1862
Query: 689 TEVEDLQLEVDR 724
+ LQ VD+
Sbjct: 1863 KNILRLQDLVDK 1874
>AK025690-1|BAB15219.1| 746|Homo sapiens protein ( Homo sapiens cDNA:
FLJ22037 fis, clone HEP08868. ).
Length = 746
Score = 211 bits (515), Expect = 2e-54
Identities = 98/235 (41%), Positives = 160/235 (68%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
++++ E ++ L ++K+K EK + +E++DL A ++ + K E V++L+ L+E
Sbjct: 363 MAELTEHVESLQRVKSKLEKDKQVMKAEIDDLNASMETIQKSKMNAEAHVRKLEDSLSEA 422
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
+K E R +++A + +L ENS+L R+ EE++S+++Q+ +IK SLT+Q++D KR
Sbjct: 423 NAKVAELERNQAEINAIRTRLQAENSELSREYEESQSRLNQILRIKTSLTSQVDDYKRQL 482
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEG 559
DEE++ R+T + N +HDLD ++EQ+EEE GK++LQR +SK N E WR+KYE++
Sbjct: 483 DEESKSRSTAVVSLANTKHDLDLVKEQLEEEQGGKSELQRLVSKLNTEVTTWRTKYETDA 542
Query: 560 VARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
+ R+EELEE KRKL ARL EAEE E+ + +LEK KQRL EVEDL +++++
Sbjct: 543 IQRTEELEETKRKLAARLQEAEEAAETAQARAASLEKNKQRLQAEVEDLTIDLEK 597
Score = 83.4 bits (197), Expect = 8e-16
Identities = 60/234 (25%), Positives = 110/234 (47%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+SDM E+L++ + A + + E++DL+ L+ L A EK + L H++ +
Sbjct: 111 ISDMRERLEEEEGMAASLSAAKRKLEGELSDLKRDLEGLETTLAKTEKEKQALDHKVRTL 170
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
++ L K+ L + L L+ E +V+ L+K L+TQ+ + +
Sbjct: 171 TGDLSLREDSITKLQKEKRALEELHQKTLDDLQAEEDKVNHLTKNNSKLSTQIHELEDNW 230
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEG 559
++E + RA + R E DL + + E K DL+ + K + E SKYE E
Sbjct: 231 EQEKKIRAEVEKARRKAESDLKMTIDNLNEMERSKLDLEEVVKKRDLEINSVNSKYEDEQ 290
Query: 560 VARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
S L+ ++ Q R+ E EE +E+ +E+ ++R A E+ L+ E++
Sbjct: 291 SLNS-TLQRKLKEHQDRIEELEEELEAERAMRAKIEQNRKREA-ELLKLRRELE 342
Score = 64.1 bits (149), Expect = 5e-10
Identities = 50/234 (21%), Positives = 107/234 (45%), Gaps = 2/234 (0%)
Frame = +2
Query: 26 DMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQS 205
D+ + D + KL+ + + ++DL+A D +++ K L Q++E++
Sbjct: 173 DLSLREDSITKLQKEKRALEELHQKTLDDLQAEEDKVNHLTKNNSK----LSTQIHELED 228
Query: 206 KADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADE 385
++ + +++ A++K + + L E E L ++ ++ ++
Sbjct: 229 NWEQEKKIRAEVEKARRKAESDLKMTIDNLNEMERSKLDLEEVVKKRDLEINSVNSKYED 288
Query: 386 EARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVA 565
E +TL K + + ++ + E++E E +A +++ + EA+L + + E E A
Sbjct: 289 EQSLNSTLQRKLKEHQDRIEELEEELEAERAMRAKIEQNRKR---EAELLKLRRELEEAA 345
Query: 566 -RSEELEEAKRKLQA-RLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
+SE RK +AE E +ESL + LEK KQ + E++DL ++
Sbjct: 346 LQSEATASTLRKKHVDSMAELTEHVESLQRVKSKLEKDKQVMKAEIDDLNASME 399
Score = 62.1 bits (144), Expect = 2e-09
Identities = 63/242 (26%), Positives = 118/242 (48%), Gaps = 11/242 (4%)
Frame = +2
Query: 29 MGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLD-HLSNEKAAQEKIV------KQLQHQ 187
M + + +NK+K EK A E NDL L N A+E++ L+ Q
Sbjct: 52 MAQTQELVNKVKELEEKT-ATLSQEKNDLTIQLQAEQENLMDAEERLTWMMKTKMDLESQ 110
Query: 188 LNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDT 367
+++++ + +E L AAK+KL E SDL R LE E+ +++ K K +L ++
Sbjct: 111 ISDMRERLEEEEGMAASLSAAKRKLEGELSDLKRDLEGLETTLAKTEKEKQALDHKVRTL 170
Query: 368 KRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQL----W 535
D RE + + K + + L+ + ++ ++ + + D L+K N++
Sbjct: 171 --TGDLSLREDS--ITKLQKEKRALEELHQKTLDDLQAEEDKVNHLTKNNSKLSTQIHEL 226
Query: 536 RSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLE 715
+E E R+ E+E+A+RK ++ L + TI++LN+ +E++K L V+ LE
Sbjct: 227 EDNWEQEKKIRA-EVEKARRKAESDL---KMTIDNLNE----MERSKLDLEEVVKKRDLE 278
Query: 716 VD 721
++
Sbjct: 279 IN 280
Score = 62.1 bits (144), Expect = 2e-09
Identities = 53/236 (22%), Positives = 115/236 (48%), Gaps = 2/236 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
V D QLD+ +K ++ A A +++ ++ L+ K+ +++V +L ++
Sbjct: 475 VDDYKRQLDEESKSRSTAVVSLANTKHDLDLVKEQLEEEQGGKSELQRLVSKLNTEVTTW 534
Query: 200 QSKAD-EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRL 376
++K + +A + +L+ K+KL+ + E A+++ + L K K L ++ED +
Sbjct: 535 RTKYETDAIQRTEELEETKRKLAARLQEAEEAAETAQARAASLEKNKQRLQAEVEDL-TI 593
Query: 377 ADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKAD-LQRQLSKANAEAQLWRSKYES 553
E+A A L K + L + +Q EE + + D Q++ E+ ++ YE
Sbjct: 594 DLEKANAAAAALDKKQRLFDKMLAEWQQKCEELQVEVDSSQKECRMYMTESFKIKTAYE- 652
Query: 554 EGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
E + E +++ + LQ + + + + + V L+K K++L E E+LQ+ ++
Sbjct: 653 ESLEHLESVKKENKTLQEEIKDLIDQLGEGGRSVHELQKLKKKLEMEKEELQVALE 708
Score = 51.2 bits (117), Expect = 4e-06
Identities = 58/228 (25%), Positives = 94/228 (41%), Gaps = 3/228 (1%)
Frame = +2
Query: 47 QLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANR 226
Q ++KAK E+ R + ++ +L + L + A + L QL Q +A
Sbjct: 37 QEEEMKAKEEELR-KAMAQTQELVNKVKELEEKTATLSQEKNDLTIQLQAEQENLMDAEE 95
Query: 227 TLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERAT 406
L + K L + SD+ +LEE E + LS K L +L D KR D E E T
Sbjct: 96 RLTWMMKTKMDLESQISDMRERLEEEEGMAASLSAAKRKLEGELSDLKR--DLEGLE--T 151
Query: 407 LLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEE--- 577
L K + LD+ + + + D +L K + K + A ++
Sbjct: 152 TLAKTEKEKQALDHKVRTLTGDLSLREDSITKLQKEKRALEELHQKTLDDLQAEEDKVNH 211
Query: 578 LEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
L + KL ++ E E+ E +K + E K R E DL++ +D
Sbjct: 212 LTKNNSKLSTQIHELEDNWE--QEKKIRAEVEKARRKAE-SDLKMTID 256
Score = 48.4 bits (110), Expect = 3e-05
Identities = 50/231 (21%), Positives = 105/231 (45%), Gaps = 9/231 (3%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQ-EKIVKQLQHQLNEVQSKA 211
EQL++ K++ ++ ++ +EV R + + ++ + E+ ++L +L E + A
Sbjct: 508 EQLEEEQGGKSELQRLVSKLNTEVTTWRTKYETDAIQRTEELEETKRKLAARLQEAEEAA 567
Query: 212 DEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEA 391
+ A L+ K++L E DL LE+A + + L K + L + ++ +E
Sbjct: 568 ETAQARAASLEKNKQRLQAEVEDLTIDLEKANAAAAALDKKQRLFDKMLAEWQQKCEELQ 627
Query: 392 RERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEA-----QLW---RSKY 547
E + + R + I+ EE E ++++ E QL RS +
Sbjct: 628 VEVDSSQKECRMYMTESFKIKTAYEESLEHLESVKKENKTLQEEIKDLIDQLGEGGRSVH 687
Query: 548 ESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVE 700
E + + + E+E K +LQ L EAE ++E KV+ ++ ++ +++
Sbjct: 688 ELQKLKKKLEME--KEELQVALEEAESSLEVEESKVIRIQLELAQVKADID 736
Score = 46.4 bits (105), Expect = 1e-04
Identities = 31/127 (24%), Positives = 65/127 (51%)
Frame = +2
Query: 14 RFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLN 193
+ +++ ++ ++L ++K Y +E ++ + + +K K LQ ++
Sbjct: 614 KMLAEWQQKCEELQVEVDSSQKECRMYMTESFKIKTAYEESLEHLESVKKENKTLQEEIK 673
Query: 194 EVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKR 373
++ + E R++++L KKKL +E +L LEEAES + ++ + KV + QLE +
Sbjct: 674 DLIDQLGEGGRSVHELQKLKKKLEMEKEELQVALEEAESSL-EVEESKV-IRIQLELAQV 731
Query: 374 LADEEAR 394
AD + R
Sbjct: 732 KADIDRR 738
Score = 39.9 bits (89), Expect = 0.010
Identities = 29/155 (18%), Positives = 64/155 (41%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
V D+ L++ N A +K + + + + + + L E + +K + + ++
Sbjct: 588 VEDLTIDLEKANAAAAALDKKQRLFDKMLAEWQQKCEELQVEVDSSQKECRMYMTESFKI 647
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
++ +E+ L + K L E DL+ QL E V +L K+K L + E+ +
Sbjct: 648 KTAYEESLEHLESVKKENKTLQEEIKDLIDQLGEGGRSVHELQKLKKKLEMEKEELQVAL 707
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGK 484
+E K ++ +L ++ ++ K
Sbjct: 708 EEAESSLEVEESKVIRIQLELAQVKADIDRRIHEK 742
>BC151242-1|AAI51243.1| 1983|Homo sapiens myosin, heavy chain 7B,
cardiac muscle, beta protein.
Length = 1983
Score = 210 bits (512), Expect = 6e-54
Identities = 106/234 (45%), Positives = 155/234 (66%)
Frame = +2
Query: 23 SDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQ 202
+++GEQ+D L +++ K EK +++ EV+DL A ++ L+ KA+ EK+ + + QL+E +
Sbjct: 1250 AELGEQVDSLQRVRQKLEKEKSELRMEVDDLAANVETLTRAKASAEKLCRTYEDQLSEAK 1309
Query: 203 SKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLAD 382
K +E R L D + +L E+ +L R LEE E +SQLS+ K LE+ +R +
Sbjct: 1310 IKVEELQRQLADASTQRGRLQTESGELSRLLEEKECLISQLSRGKALAAQSLEELRRQLE 1369
Query: 383 EEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGV 562
EE++ ++ L + L HD D +REQ EEEAE +A+LQR LSKANAE WRSKYE++ +
Sbjct: 1370 EESKAKSALAHAVQALRHDCDLLREQHEEEAEAQAELQRLLSKANAEVAQWRSKYEADAI 1429
Query: 563 ARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
R+EELEEAK+KL RL EAEE +E+ N K +LEK K RL TE ED+ LE++R
Sbjct: 1430 QRTEELEEAKKKLALRLQEAEEGVEAANAKCSSLEKAKLRLQTESEDVTLELER 1483
Score = 77.8 bits (183), Expect = 4e-14
Identities = 67/243 (27%), Positives = 115/243 (47%), Gaps = 7/243 (2%)
Frame = +2
Query: 14 RFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLN 193
R V + LD + + +A + + + ++NDL L H + + + + +Q QL
Sbjct: 1641 RAVESLQASLDAETRARNEALRLKKKMEGDLNDLELQLGHATRQATEAQAATRLMQAQLK 1700
Query: 194 EVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIK-VSLTTQLEDTK 370
E Q+ DE R +L + L S L +LEE + + Q + + ++ LE T+
Sbjct: 1701 EEQAGRDEEQRLAAELHEQAQALERRASLLAAELEELRAALEQGERSRRLAEQELLEATE 1760
Query: 371 RLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRS--K 544
RL ++ LL + + LE DL + +VEE A+ + + + + KA +A + K
Sbjct: 1761 RLNLLHSQNTG-LLNQKKKLEADLAQLSGEVEEAAQERREAEEKAKKAITDAAMMAEELK 1819
Query: 545 YESEGVARSEE----LEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQL 712
E + A E LE+ R+LQARL EAE+ +K V Q+L +V +L+
Sbjct: 1820 KEQDTSAHLERMKKTLEQTVRELQARLEEAEQAALRGGKKQV------QKLEAKVRELEA 1873
Query: 713 EVD 721
E+D
Sbjct: 1874 ELD 1876
Score = 69.3 bits (162), Expect = 1e-11
Identities = 56/216 (25%), Positives = 93/216 (43%), Gaps = 1/216 (0%)
Frame = +2
Query: 77 KXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKK 256
K + + +V DL L+ + E+ ++L+ L Q +A + L+ K
Sbjct: 1071 KAKLRLEQQVEDLECSLEQEKKLRMDTERAKRKLEGDLKLTQESVADAAQDKQQLEEKLK 1130
Query: 257 KLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEH 436
K E S L ++E+ + +Q+ K L + E+ + + E RA + +
Sbjct: 1131 KKDSELSQLSLRVEDEQLLGAQMQKKIKELQARAEELEEELEAERAARARVEKQRAEAAR 1190
Query: 437 DLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQAR-L 613
+L+ + E++EE A + K AE R + E E R E A R+ QA
Sbjct: 1191 ELEELSERLEEAGGASAGQREGCRKREAELGRLRRELE-EAALRHEATVAALRRKQAEGA 1249
Query: 614 AEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
AE E ++SL + LEK K L EV+DL V+
Sbjct: 1250 AELGEQVDSLQRVRQKLEKEKSELRMEVDDLAANVE 1285
Score = 49.6 bits (113), Expect = 1e-05
Identities = 35/158 (22%), Positives = 76/158 (48%), Gaps = 1/158 (0%)
Frame = +2
Query: 29 MGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKA-AQEKIVKQLQHQLNEVQS 205
M E+L + A E+ + V +L+A L+ +K V++L+ ++ E+++
Sbjct: 1814 MAEELKKEQDTSAHLERMKKTLEQTVRELQARLEEAEQAALRGGKKQVQKLEAKVRELEA 1873
Query: 206 KADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADE 385
+ D + + +K +L Q EE ++++ + L ++++ KR +E
Sbjct: 1874 ELDAEQKKHAEALKGVRKHERRVKELAYQAEEDRKNLARMQDLVDKLQSKVKSYKRQFEE 1933
Query: 386 EARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQR 499
++ T L K+R +H+LD+ E+ + AE +A+ R
Sbjct: 1934 AEQQANTNLAKYRKAQHELDDAEERA-DMAETQANKLR 1970
Score = 43.2 bits (97), Expect = 0.001
Identities = 43/151 (28%), Positives = 72/151 (47%), Gaps = 5/151 (3%)
Frame = +2
Query: 287 RQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFR-NLEHDLDNIREQV 463
++LEE ++Q K ++L Q E LAD E ER LL K + LE + + E++
Sbjct: 920 QELEETHVSITQ-EKNDLALQLQAEQDN-LADAE--ERCHLLIKSKVQLEGKVKELSERL 975
Query: 464 EEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESL 643
E+E E ADL + K E + + + + + E+ K+ + ++ E + +L
Sbjct: 976 EDEEEVNADLAARRRKLEDECTELKKDIDDLELTLA-KAEKEKQATENKVKNLTEEMAAL 1034
Query: 644 NQKVVALEKTKQRL----ATEVEDLQLEVDR 724
++ V L K K+ L + DLQ E DR
Sbjct: 1035 DESVARLTKEKKALQEAHQQALGDLQAEEDR 1065
Score = 34.3 bits (75), Expect = 0.50
Identities = 31/86 (36%), Positives = 45/86 (52%), Gaps = 4/86 (4%)
Frame = +2
Query: 458 QVEEE-AEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQAR---LAEAE 625
Q EEE A +A+L R L A A A+ R + E V+ ++E + +LQA LA+AE
Sbjct: 893 QAEEELAALRAEL-RGLRGALAAAEAKRQELEETHVSITQEKNDLALQLQAEQDNLADAE 951
Query: 626 ETIESLNQKVVALEKTKQRLATEVED 703
E L + V LE + L+ +ED
Sbjct: 952 ERCHLLIKSKVQLEGKVKELSERLED 977
>BC007808-1|AAH07808.1| 1006|Homo sapiens MYH7B protein protein.
Length = 1006
Score = 210 bits (512), Expect = 6e-54
Identities = 106/234 (45%), Positives = 155/234 (66%)
Frame = +2
Query: 23 SDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQ 202
+++GEQ+D L +++ K EK +++ EV+DL A ++ L+ KA+ EK+ + + QL+E +
Sbjct: 273 AELGEQVDSLQRVRQKLEKEKSELRMEVDDLAANVETLTRAKASAEKLCRTYEDQLSEAK 332
Query: 203 SKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLAD 382
K +E R L D + +L E+ +L R LEE E +SQLS+ K LE+ +R +
Sbjct: 333 IKVEELQRQLADASTQRGRLQTESGELSRLLEEKECLISQLSRGKALAAQSLEELRRQLE 392
Query: 383 EEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGV 562
EE++ ++ L + L HD D +REQ EEEAE +A+LQR LSKANAE WRSKYE++ +
Sbjct: 393 EESKAKSALAHAVQALRHDCDLLREQHEEEAEAQAELQRLLSKANAEVAQWRSKYEADAI 452
Query: 563 ARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
R+EELEEAK+KL RL EAEE +E+ N K +LEK K RL TE ED+ LE++R
Sbjct: 453 QRTEELEEAKKKLALRLQEAEEGVEAANAKCSSLEKAKLRLQTESEDVTLELER 506
Score = 77.8 bits (183), Expect = 4e-14
Identities = 67/243 (27%), Positives = 115/243 (47%), Gaps = 7/243 (2%)
Frame = +2
Query: 14 RFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLN 193
R V + LD + + +A + + + ++NDL L H + + + + +Q QL
Sbjct: 664 RAVESLQASLDAETRARNEALRLKKKMEGDLNDLELQLGHATRQATEAQAATRLMQAQLK 723
Query: 194 EVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIK-VSLTTQLEDTK 370
E Q+ DE R +L + L S L +LEE + + Q + + ++ LE T+
Sbjct: 724 EEQAGRDEEQRLAAELHEQAQALERRASLLAAELEELRAALEQGERSRRLAEQELLEATE 783
Query: 371 RLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRS--K 544
RL ++ LL + + LE DL + +VEE A+ + + + + KA +A + K
Sbjct: 784 RLNLLHSQNTG-LLNQKKKLEADLAQLSGEVEEAAQERREAEEKAKKAITDAAMMAEELK 842
Query: 545 YESEGVARSEE----LEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQL 712
E + A E LE+ R+LQARL EAE+ +K V Q+L +V +L+
Sbjct: 843 KEQDTSAHLERMKKTLEQTVRELQARLEEAEQAALRGGKKQV------QKLEAKVRELEA 896
Query: 713 EVD 721
E+D
Sbjct: 897 ELD 899
Score = 69.3 bits (162), Expect = 1e-11
Identities = 56/216 (25%), Positives = 93/216 (43%), Gaps = 1/216 (0%)
Frame = +2
Query: 77 KXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKK 256
K + + +V DL L+ + E+ ++L+ L Q +A + L+ K
Sbjct: 94 KAKLRLEQQVEDLECSLEQEKKLRMDTERAKRKLEGDLKLTQESVADAAQDKQQLEEKLK 153
Query: 257 KLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEH 436
K E S L ++E+ + +Q+ K L + E+ + + E RA + +
Sbjct: 154 KKDSELSQLSLRVEDEQLLGAQMQKKIKELQARAEELEEELEAERAARARVEKQRAEAAR 213
Query: 437 DLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQAR-L 613
+L+ + E++EE A + K AE R + E E R E A R+ QA
Sbjct: 214 ELEELSERLEEAGGASAGQREGCRKREAELGRLRRELE-EAALRHEATVAALRRKQAEGA 272
Query: 614 AEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
AE E ++SL + LEK K L EV+DL V+
Sbjct: 273 AELGEQVDSLQRVRQKLEKEKSELRMEVDDLAANVE 308
Score = 49.6 bits (113), Expect = 1e-05
Identities = 35/158 (22%), Positives = 76/158 (48%), Gaps = 1/158 (0%)
Frame = +2
Query: 29 MGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKA-AQEKIVKQLQHQLNEVQS 205
M E+L + A E+ + V +L+A L+ +K V++L+ ++ E+++
Sbjct: 837 MAEELKKEQDTSAHLERMKKTLEQTVRELQARLEEAEQAALRGGKKQVQKLEAKVRELEA 896
Query: 206 KADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADE 385
+ D + + +K +L Q EE ++++ + L ++++ KR +E
Sbjct: 897 ELDAEQKKHAEALKGVRKHERRVKELAYQAEEDRKNLARMQDLVDKLQSKVKSYKRQFEE 956
Query: 386 EARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQR 499
++ T L K+R +H+LD+ E+ + AE +A+ R
Sbjct: 957 AEQQANTNLAKYRKAQHELDDAEERA-DMAETQANKLR 993
>AL133324-2|CAI19310.2| 1983|Homo sapiens myosin, heavy chain 7B,
cardiac muscle, beta protein.
Length = 1983
Score = 210 bits (512), Expect = 6e-54
Identities = 106/234 (45%), Positives = 155/234 (66%)
Frame = +2
Query: 23 SDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQ 202
+++GEQ+D L +++ K EK +++ EV+DL A ++ L+ KA+ EK+ + + QL+E +
Sbjct: 1250 AELGEQVDSLQRVRQKLEKEKSELRMEVDDLAANVETLTRAKASAEKLCRTYEDQLSEAK 1309
Query: 203 SKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLAD 382
K +E R L D + +L E+ +L R LEE E +SQLS+ K LE+ +R +
Sbjct: 1310 IKVEELQRQLADASTQRGRLQTESGELSRLLEEKECLISQLSRGKALAAQSLEELRRQLE 1369
Query: 383 EEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGV 562
EE++ ++ L + L HD D +REQ EEEAE +A+LQR LSKANAE WRSKYE++ +
Sbjct: 1370 EESKAKSALAHAVQALRHDCDLLREQHEEEAEAQAELQRLLSKANAEVAQWRSKYEADAI 1429
Query: 563 ARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
R+EELEEAK+KL RL EAEE +E+ N K +LEK K RL TE ED+ LE++R
Sbjct: 1430 QRTEELEEAKKKLALRLQEAEEGVEAANAKCSSLEKAKLRLQTESEDVTLELER 1483
Score = 77.8 bits (183), Expect = 4e-14
Identities = 67/243 (27%), Positives = 115/243 (47%), Gaps = 7/243 (2%)
Frame = +2
Query: 14 RFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLN 193
R V + LD + + +A + + + ++NDL L H + + + + +Q QL
Sbjct: 1641 RAVESLQASLDAETRARNEALRLKKKMEGDLNDLELQLGHATRQATEAQAATRLMQAQLK 1700
Query: 194 EVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIK-VSLTTQLEDTK 370
E Q+ DE R +L + L S L +LEE + + Q + + ++ LE T+
Sbjct: 1701 EEQAGRDEEQRLAAELHEQAQALERRASLLAAELEELRAALEQGERSRRLAEQELLEATE 1760
Query: 371 RLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRS--K 544
RL ++ LL + + LE DL + +VEE A+ + + + + KA +A + K
Sbjct: 1761 RLNLLHSQNTG-LLNQKKKLEADLAQLSGEVEEAAQERREAEEKAKKAITDAAMMAEELK 1819
Query: 545 YESEGVARSEE----LEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQL 712
E + A E LE+ R+LQARL EAE+ +K V Q+L +V +L+
Sbjct: 1820 KEQDTSAHLERMKKTLEQTVRELQARLEEAEQAALRGGKKQV------QKLEAKVRELEA 1873
Query: 713 EVD 721
E+D
Sbjct: 1874 ELD 1876
Score = 69.3 bits (162), Expect = 1e-11
Identities = 56/216 (25%), Positives = 93/216 (43%), Gaps = 1/216 (0%)
Frame = +2
Query: 77 KXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKK 256
K + + +V DL L+ + E+ ++L+ L Q +A + L+ K
Sbjct: 1071 KAKLRLEQQVEDLECSLEQEKKLRMDTERAKRKLEGDLKLTQESVADAAQDKQQLEEKLK 1130
Query: 257 KLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEH 436
K E S L ++E+ + +Q+ K L + E+ + + E RA + +
Sbjct: 1131 KKDSELSQLSLRVEDEQLLGAQMQKKIKELQARAEELEEELEAERAARARVEKQRAEAAR 1190
Query: 437 DLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQAR-L 613
+L+ + E++EE A + K AE R + E E R E A R+ QA
Sbjct: 1191 ELEELSERLEEAGGASAGQREGCRKREAELGRLRRELE-EAALRHEATVAALRRKQAEGA 1249
Query: 614 AEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
AE E ++SL + LEK K L EV+DL V+
Sbjct: 1250 AELGEQVDSLQRVRQKLEKEKSELRMEVDDLAANVE 1285
Score = 52.8 bits (121), Expect = 1e-06
Identities = 52/201 (25%), Positives = 94/201 (46%), Gaps = 7/201 (3%)
Frame = +2
Query: 143 EKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQ 322
E AA ++ L+ L ++K E T + K L+++ L +AE +
Sbjct: 897 ELAALRAELRGLRGALAAAEAKRQELEETHVSITQEKNDLALQLQAEQDNLADAEERCHL 956
Query: 323 LSKIKVSLTTQLED-TKRLADEE------ARERATLLGKFRNLEHDLDNIREQVEEEAEG 481
L K KV L ++++ ++RL DEE A R L + L+ D+D+++ +
Sbjct: 957 LIKSKVQLEGKVKELSERLEDEEEVNADLAARRRKLEDECTELKKDIDDLKLTL-----A 1011
Query: 482 KADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVA 661
KA+ ++Q ++ + E VAR L + K+ LQ +A +++ +V A
Sbjct: 1012 KAEKEKQATENKVKNLTEEMAALDESVAR---LTKEKKALQEAHQQALGDLQAEEDRVSA 1068
Query: 662 LEKTKQRLATEVEDLQLEVDR 724
L K K RL +VEDL+ +++
Sbjct: 1069 LTKAKLRLEQQVEDLECSLEQ 1089
Score = 49.6 bits (113), Expect = 1e-05
Identities = 35/158 (22%), Positives = 76/158 (48%), Gaps = 1/158 (0%)
Frame = +2
Query: 29 MGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKA-AQEKIVKQLQHQLNEVQS 205
M E+L + A E+ + V +L+A L+ +K V++L+ ++ E+++
Sbjct: 1814 MAEELKKEQDTSAHLERMKKTLEQTVRELQARLEEAEQAALRGGKKQVQKLEAKVRELEA 1873
Query: 206 KADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADE 385
+ D + + +K +L Q EE ++++ + L ++++ KR +E
Sbjct: 1874 ELDAEQKKHAEALKGVRKHERRVKELAYQAEEDRKNLARMQDLVDKLQSKVKSYKRQFEE 1933
Query: 386 EARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQR 499
++ T L K+R +H+LD+ E+ + AE +A+ R
Sbjct: 1934 AEQQANTNLAKYRKAQHELDDAEERA-DMAETQANKLR 1970
Score = 34.3 bits (75), Expect = 0.50
Identities = 31/86 (36%), Positives = 45/86 (52%), Gaps = 4/86 (4%)
Frame = +2
Query: 458 QVEEE-AEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQAR---LAEAE 625
Q EEE A +A+L R L A A A+ R + E V+ ++E + +LQA LA+AE
Sbjct: 893 QAEEELAALRAEL-RGLRGALAAAEAKRQELEETHVSITQEKNDLALQLQAEQDNLADAE 951
Query: 626 ETIESLNQKVVALEKTKQRLATEVED 703
E L + V LE + L+ +ED
Sbjct: 952 ERCHLLIKSKVQLEGKVKELSERLED 977
>AL132825-6|CAI43047.2| 1983|Homo sapiens myosin, heavy chain 7B,
cardiac muscle, beta protein.
Length = 1983
Score = 210 bits (512), Expect = 6e-54
Identities = 106/234 (45%), Positives = 155/234 (66%)
Frame = +2
Query: 23 SDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQ 202
+++GEQ+D L +++ K EK +++ EV+DL A ++ L+ KA+ EK+ + + QL+E +
Sbjct: 1250 AELGEQVDSLQRVRQKLEKEKSELRMEVDDLAANVETLTRAKASAEKLCRTYEDQLSEAK 1309
Query: 203 SKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLAD 382
K +E R L D + +L E+ +L R LEE E +SQLS+ K LE+ +R +
Sbjct: 1310 IKVEELQRQLADASTQRGRLQTESGELSRLLEEKECLISQLSRGKALAAQSLEELRRQLE 1369
Query: 383 EEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGV 562
EE++ ++ L + L HD D +REQ EEEAE +A+LQR LSKANAE WRSKYE++ +
Sbjct: 1370 EESKAKSALAHAVQALRHDCDLLREQHEEEAEAQAELQRLLSKANAEVAQWRSKYEADAI 1429
Query: 563 ARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
R+EELEEAK+KL RL EAEE +E+ N K +LEK K RL TE ED+ LE++R
Sbjct: 1430 QRTEELEEAKKKLALRLQEAEEGVEAANAKCSSLEKAKLRLQTESEDVTLELER 1483
Score = 77.8 bits (183), Expect = 4e-14
Identities = 67/243 (27%), Positives = 115/243 (47%), Gaps = 7/243 (2%)
Frame = +2
Query: 14 RFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLN 193
R V + LD + + +A + + + ++NDL L H + + + + +Q QL
Sbjct: 1641 RAVESLQASLDAETRARNEALRLKKKMEGDLNDLELQLGHATRQATEAQAATRLMQAQLK 1700
Query: 194 EVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIK-VSLTTQLEDTK 370
E Q+ DE R +L + L S L +LEE + + Q + + ++ LE T+
Sbjct: 1701 EEQAGRDEEQRLAAELHEQAQALERRASLLAAELEELRAALEQGERSRRLAEQELLEATE 1760
Query: 371 RLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRS--K 544
RL ++ LL + + LE DL + +VEE A+ + + + + KA +A + K
Sbjct: 1761 RLNLLHSQNTG-LLNQKKKLEADLAQLSGEVEEAAQERREAEEKAKKAITDAAMMAEELK 1819
Query: 545 YESEGVARSEE----LEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQL 712
E + A E LE+ R+LQARL EAE+ +K V Q+L +V +L+
Sbjct: 1820 KEQDTSAHLERMKKTLEQTVRELQARLEEAEQAALRGGKKQV------QKLEAKVRELEA 1873
Query: 713 EVD 721
E+D
Sbjct: 1874 ELD 1876
Score = 69.3 bits (162), Expect = 1e-11
Identities = 56/216 (25%), Positives = 93/216 (43%), Gaps = 1/216 (0%)
Frame = +2
Query: 77 KXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKK 256
K + + +V DL L+ + E+ ++L+ L Q +A + L+ K
Sbjct: 1071 KAKLRLEQQVEDLECSLEQEKKLRMDTERAKRKLEGDLKLTQESVADAAQDKQQLEEKLK 1130
Query: 257 KLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEH 436
K E S L ++E+ + +Q+ K L + E+ + + E RA + +
Sbjct: 1131 KKDSELSQLSLRVEDEQLLGAQMQKKIKELQARAEELEEELEAERAARARVEKQRAEAAR 1190
Query: 437 DLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQAR-L 613
+L+ + E++EE A + K AE R + E E R E A R+ QA
Sbjct: 1191 ELEELSERLEEAGGASAGQREGCRKREAELGRLRRELE-EAALRHEATVAALRRKQAEGA 1249
Query: 614 AEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
AE E ++SL + LEK K L EV+DL V+
Sbjct: 1250 AELGEQVDSLQRVRQKLEKEKSELRMEVDDLAANVE 1285
Score = 52.8 bits (121), Expect = 1e-06
Identities = 52/201 (25%), Positives = 94/201 (46%), Gaps = 7/201 (3%)
Frame = +2
Query: 143 EKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQ 322
E AA ++ L+ L ++K E T + K L+++ L +AE +
Sbjct: 897 ELAALRAELRGLRGALAAAEAKRQELEETHVSITQEKNDLALQLQAEQDNLADAEERCHL 956
Query: 323 LSKIKVSLTTQLED-TKRLADEE------ARERATLLGKFRNLEHDLDNIREQVEEEAEG 481
L K KV L ++++ ++RL DEE A R L + L+ D+D+++ +
Sbjct: 957 LIKSKVQLEGKVKELSERLEDEEEVNADLAARRRKLEDECTELKKDIDDLKLTL-----A 1011
Query: 482 KADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVA 661
KA+ ++Q ++ + E VAR L + K+ LQ +A +++ +V A
Sbjct: 1012 KAEKEKQATENKVKNLTEEMAALDESVAR---LTKEKKALQEAHQQALGDLQAEEDRVSA 1068
Query: 662 LEKTKQRLATEVEDLQLEVDR 724
L K K RL +VEDL+ +++
Sbjct: 1069 LTKAKLRLEQQVEDLECSLEQ 1089
Score = 49.6 bits (113), Expect = 1e-05
Identities = 35/158 (22%), Positives = 76/158 (48%), Gaps = 1/158 (0%)
Frame = +2
Query: 29 MGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKA-AQEKIVKQLQHQLNEVQS 205
M E+L + A E+ + V +L+A L+ +K V++L+ ++ E+++
Sbjct: 1814 MAEELKKEQDTSAHLERMKKTLEQTVRELQARLEEAEQAALRGGKKQVQKLEAKVRELEA 1873
Query: 206 KADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADE 385
+ D + + +K +L Q EE ++++ + L ++++ KR +E
Sbjct: 1874 ELDAEQKKHAEALKGVRKHERRVKELAYQAEEDRKNLARMQDLVDKLQSKVKSYKRQFEE 1933
Query: 386 EARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQR 499
++ T L K+R +H+LD+ E+ + AE +A+ R
Sbjct: 1934 AEQQANTNLAKYRKAQHELDDAEERA-DMAETQANKLR 1970
Score = 34.3 bits (75), Expect = 0.50
Identities = 31/86 (36%), Positives = 45/86 (52%), Gaps = 4/86 (4%)
Frame = +2
Query: 458 QVEEE-AEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQAR---LAEAE 625
Q EEE A +A+L R L A A A+ R + E V+ ++E + +LQA LA+AE
Sbjct: 893 QAEEELAALRAEL-RGLRGALAAAEAKRQELEETHVSITQEKNDLALQLQAEQDNLADAE 951
Query: 626 ETIESLNQKVVALEKTKQRLATEVED 703
E L + V LE + L+ +ED
Sbjct: 952 ERCHLLIKSKVQLEGKVKELSERLED 977
>AB040945-1|BAA96036.2| 2010|Homo sapiens KIAA1512 protein protein.
Length = 2010
Score = 210 bits (512), Expect = 6e-54
Identities = 106/234 (45%), Positives = 155/234 (66%)
Frame = +2
Query: 23 SDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQ 202
+++GEQ+D L +++ K EK +++ EV+DL A ++ L+ KA+ EK+ + + QL+E +
Sbjct: 1277 AELGEQVDSLQRVRQKLEKEKSELRMEVDDLAANVETLTRAKASAEKLCRTYEDQLSEAK 1336
Query: 203 SKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLAD 382
K +E R L D + +L E+ +L R LEE E +SQLS+ K LE+ +R +
Sbjct: 1337 IKVEELQRQLADASTQRGRLQTESGELSRLLEEKECLISQLSRGKALAAQSLEELRRQLE 1396
Query: 383 EEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGV 562
EE++ ++ L + L HD D +REQ EEEAE +A+LQR LSKANAE WRSKYE++ +
Sbjct: 1397 EESKAKSALAHAVQALRHDCDLLREQHEEEAEAQAELQRLLSKANAEVAQWRSKYEADAI 1456
Query: 563 ARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
R+EELEEAK+KL RL EAEE +E+ N K +LEK K RL TE ED+ LE++R
Sbjct: 1457 QRTEELEEAKKKLALRLQEAEEGVEAANAKCSSLEKAKLRLQTESEDVTLELER 1510
Score = 77.8 bits (183), Expect = 4e-14
Identities = 67/243 (27%), Positives = 115/243 (47%), Gaps = 7/243 (2%)
Frame = +2
Query: 14 RFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLN 193
R V + LD + + +A + + + ++NDL L H + + + + +Q QL
Sbjct: 1668 RAVESLQASLDAETRARNEALRLKKKMEGDLNDLELQLGHATRQATEAQAATRLMQAQLK 1727
Query: 194 EVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIK-VSLTTQLEDTK 370
E Q+ DE R +L + L S L +LEE + + Q + + ++ LE T+
Sbjct: 1728 EEQAGRDEEQRLAAELHEQAQALERRASLLAAELEELRAALEQGERSRRLAEQELLEATE 1787
Query: 371 RLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRS--K 544
RL ++ LL + + LE DL + +VEE A+ + + + + KA +A + K
Sbjct: 1788 RLNLLHSQNTG-LLNQKKKLEADLAQLSGEVEEAAQERREAEEKAKKAITDAAMMAEELK 1846
Query: 545 YESEGVARSEE----LEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQL 712
E + A E LE+ R+LQARL EAE+ +K V Q+L +V +L+
Sbjct: 1847 KEQDTSAHLERMKKTLEQTVRELQARLEEAEQAALRGGKKQV------QKLEAKVRELEA 1900
Query: 713 EVD 721
E+D
Sbjct: 1901 ELD 1903
Score = 69.3 bits (162), Expect = 1e-11
Identities = 56/216 (25%), Positives = 93/216 (43%), Gaps = 1/216 (0%)
Frame = +2
Query: 77 KXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKK 256
K + + +V DL L+ + E+ ++L+ L Q +A + L+ K
Sbjct: 1098 KAKLRLEQQVEDLECSLEQEKKLRMDTERAKRKLEGDLKLTQESVADAAQDKQQLEEKLK 1157
Query: 257 KLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEH 436
K E S L ++E+ + +Q+ K L + E+ + + E RA + +
Sbjct: 1158 KKDSELSQLSLRVEDEQLLGAQMQKKIKELQARAEELEEELEAERAARARVEKQRAEAAR 1217
Query: 437 DLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQAR-L 613
+L+ + E++EE A + K AE R + E E R E A R+ QA
Sbjct: 1218 ELEELSERLEEAGGASAGQREGCRKREAELGRLRRELE-EAALRHEATVAALRRKQAEGA 1276
Query: 614 AEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
AE E ++SL + LEK K L EV+DL V+
Sbjct: 1277 AELGEQVDSLQRVRQKLEKEKSELRMEVDDLAANVE 1312
Score = 49.6 bits (113), Expect = 1e-05
Identities = 35/158 (22%), Positives = 76/158 (48%), Gaps = 1/158 (0%)
Frame = +2
Query: 29 MGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKA-AQEKIVKQLQHQLNEVQS 205
M E+L + A E+ + V +L+A L+ +K V++L+ ++ E+++
Sbjct: 1841 MAEELKKEQDTSAHLERMKKTLEQTVRELQARLEEAEQAALRGGKKQVQKLEAKVRELEA 1900
Query: 206 KADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADE 385
+ D + + +K +L Q EE ++++ + L ++++ KR +E
Sbjct: 1901 ELDAEQKKHAEALKGVRKHERRVKELAYQAEEDRKNLARMQDLVDKLQSKVKSYKRQFEE 1960
Query: 386 EARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQR 499
++ T L K+R +H+LD+ E+ + AE +A+ R
Sbjct: 1961 AEQQANTNLAKYRKAQHELDDAEERA-DMAETQANKLR 1997
Score = 43.2 bits (97), Expect = 0.001
Identities = 43/151 (28%), Positives = 72/151 (47%), Gaps = 5/151 (3%)
Frame = +2
Query: 287 RQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFR-NLEHDLDNIREQV 463
++LEE ++Q K ++L Q E LAD E ER LL K + LE + + E++
Sbjct: 947 QELEETHVSITQ-EKNDLALQLQAEQDN-LADAE--ERCHLLIKSKVQLEGKVKELSERL 1002
Query: 464 EEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESL 643
E+E E ADL + K E + + + + + E+ K+ + ++ E + +L
Sbjct: 1003 EDEEEVNADLAARRRKLEDECTELKKDIDDLELTLA-KAEKEKQATENKVKNLTEEMAAL 1061
Query: 644 NQKVVALEKTKQRL----ATEVEDLQLEVDR 724
++ V L K K+ L + DLQ E DR
Sbjct: 1062 DESVARLTKEKKALQEAHQQALGDLQAEEDR 1092
Score = 34.3 bits (75), Expect = 0.50
Identities = 31/86 (36%), Positives = 45/86 (52%), Gaps = 4/86 (4%)
Frame = +2
Query: 458 QVEEE-AEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQAR---LAEAE 625
Q EEE A +A+L R L A A A+ R + E V+ ++E + +LQA LA+AE
Sbjct: 920 QAEEELAALRAEL-RGLRGALAAAEAKRQELEETHVSITQEKNDLALQLQAEQDNLADAE 978
Query: 626 ETIESLNQKVVALEKTKQRLATEVED 703
E L + V LE + L+ +ED
Sbjct: 979 ERCHLLIKSKVQLEGKVKELSERLED 1004
>X51592-1|CAA35941.1| 1437|Homo sapiens fetal-myosin heavy chain (1437
AA) protein.
Length = 1437
Score = 209 bits (511), Expect = 7e-54
Identities = 105/236 (44%), Positives = 158/236 (66%), Gaps = 1/236 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIV-KQLQHQLNE 196
++++GEQ+D L ++K K EK +++ E +DL + + +S K EK + L+ Q++E
Sbjct: 702 MAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKDGGRSLEDQVSE 761
Query: 197 VQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRL 376
+++K +E R +NDL A + +L E + RQL+E ++ VSQLS+ K + T Q+E+ K
Sbjct: 762 LKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQ 821
Query: 377 ADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESE 556
+EE + + L ++ HD D +REQ EEE EGKA+LQR LSKAN+E WR+ E++
Sbjct: 822 LEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTNTETD 881
Query: 557 GVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
+ R+EELEEAK+KL RL EAEE +E++N K +LEKTKQRL EVEDL L+V+R
Sbjct: 882 AIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVER 937
Score = 72.9 bits (171), Expect = 1e-12
Identities = 63/231 (27%), Positives = 106/231 (45%), Gaps = 2/231 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+ D+ + D++N L K + + +V+DL L+ + E+ ++L+ L
Sbjct: 509 LDDLQAEEDKVNILT----KAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLA 564
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
Q + LD +K E S+L+ ++E+ ++ QL K L ++E+
Sbjct: 565 QESTMDNENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEI 624
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLS-KANAEAQLWRSKYESE 556
+ E RA + +L +L+ I E++ EEA G Q +L+ K AE Q R E E
Sbjct: 625 EAERASRAKAEKQRSDLSRELEEISERL-EEAGGATSAQVELNKKREAEFQKLRRDLE-E 682
Query: 557 GVARSEELEEAKRKLQA-RLAEAEETIESLNQKVVALEKTKQRLATEVEDL 706
+ E + A RK A +AE E I++L + LEK K L E +DL
Sbjct: 683 ATLQHEAMVAALRKKHADSMAELGEQIDNLQRVKQKLEKEKSELKMETDDL 733
Score = 64.9 bits (151), Expect = 3e-10
Identities = 50/231 (21%), Positives = 104/231 (45%), Gaps = 1/231 (0%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQ-EKIVKQLQHQLNEVQSKA 211
EQ ++ + KA+ ++ ++ SEV R + + ++ + E+ K+L +L E +
Sbjct: 848 EQYEEEQEGKAELQRALSKANSEVAQWRTNTETDAIQRTEELEEAKKKLAQRLQEAEEHV 907
Query: 212 DEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEA 391
+ N L+ K++L E DL+ +E + + + L K + + L + K+ +E
Sbjct: 908 EAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQ 967
Query: 392 RERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARS 571
E + R+L +L ++ EE + L+R+ E + +EG +
Sbjct: 968 AELEASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQI-AEGGKQI 1026
Query: 572 EELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
ELE+ K++++ E + +E + E R+ E+ ++ EVDR
Sbjct: 1027 HELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDR 1077
Score = 62.1 bits (144), Expect = 2e-09
Identities = 59/242 (24%), Positives = 112/242 (46%), Gaps = 10/242 (4%)
Frame = +2
Query: 14 RFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLN 193
R V M LD + + A + + + ++N++ L+H + A + + Q L
Sbjct: 1095 RVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQGILK 1154
Query: 194 EVQSKADEANRTLNDLDAAKKKLSI--ENSDLLR-QLEEAESQVSQLSKIKVSLTTQLED 364
E Q D+A R DL K++L+I ++LL+ ++EE + + Q + + +L D
Sbjct: 1155 ETQLHLDDALRGQEDL---KEQLAIVERRANLLQAEIEELWATLEQTERSRKIAEQELLD 1211
Query: 365 TKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRS- 541
+ +L+ + LE+D+ ++ +VEE + + + + KA +A +
Sbjct: 1212 ASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEE 1271
Query: 542 -KYESEGVARSE----ELEEAKRKLQARLAEAEE-TIESLNQKVVALEKTKQRLATEVED 703
K E + A E LE+ + LQ RL EAE+ ++ +++ LE + L EVE+
Sbjct: 1272 LKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVEN 1331
Query: 704 LQ 709
Q
Sbjct: 1332 EQ 1333
Score = 60.9 bits (141), Expect = 5e-09
Identities = 48/214 (22%), Positives = 108/214 (50%), Gaps = 10/214 (4%)
Frame = +2
Query: 68 KAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDA 247
+A+K AQ E + ++ ++ + A+ EK ++LQ+++ ++ + +N LD
Sbjct: 891 EAKKKLAQRLQEAEE---HVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDK 947
Query: 248 AKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRN 427
++ S+ ++ EE ++++ K SL+T+L K + +E + TL + +N
Sbjct: 948 KQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRRENKN 1007
Query: 428 LEHDLDNIREQVEEEAEGKADLQ---RQLSKANAEAQLWRSKYES-----EG-VARSE-E 577
L+ ++ ++ EQ+ E + +L+ +Q+ + E Q + E+ EG + R + E
Sbjct: 1008 LQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLE 1067
Query: 578 LEEAKRKLQARLAEAEETIESLNQKVVALEKTKQ 679
L + K ++ ++AE +E I+ L + + +T Q
Sbjct: 1068 LNQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQ 1101
Score = 60.5 bits (140), Expect = 7e-09
Identities = 48/235 (20%), Positives = 106/235 (45%), Gaps = 1/235 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
V D+ +++ N A +K + + +++ + + E A +K + L +L +V
Sbjct: 928 VEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKV 987
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
++ +E+ L L K L E SDL Q+ E Q+ +L KIK + + + +
Sbjct: 988 KNVYEESLDQLETLRRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAAL 1047
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAE-AQLWRSKYESE 556
+E GK ++ +L+ ++ +V+ + K + QL + + + +S ++E
Sbjct: 1048 EEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQSTLDAE 1107
Query: 557 GVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
+R++ L K+K++ L E E + N+ + + +++ QL +D
Sbjct: 1108 IRSRNDAL-RVKKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQGILKETQLHLD 1161
Score = 58.0 bits (134), Expect = 4e-08
Identities = 50/236 (21%), Positives = 108/236 (45%), Gaps = 2/236 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+ ++ QL++ K K + + LR + KA ++ + + ++ +
Sbjct: 815 IEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQW 874
Query: 200 QSKAD-EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRL 376
++ + +A + +L+ AKKKL+ + +E ++ + L K K L ++ED
Sbjct: 875 RTNTETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLD 934
Query: 377 ADEEARERATLLGKFRNLEHDLDNIREQVEE-EAEGKADLQRQLSKANAEAQLWRSKYES 553
+ A L K RN + L +++ EE +AE +A Q++ + E ++ YE
Sbjct: 935 VERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEAS-QKESRSLSTELFKVKNVYE- 992
Query: 554 EGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
E + + E L + LQ +++ E I +++ LEK K+++ E ++Q ++
Sbjct: 993 ESLDQLETLRRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALE 1048
Score = 53.6 bits (123), Expect = 8e-07
Identities = 48/226 (21%), Positives = 99/226 (43%), Gaps = 2/226 (0%)
Frame = +2
Query: 26 DMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNE-KAAQEKIVKQLQHQLNEVQ 202
D E++ L+ + + ++V+ L++ ++ + E + A+EK K + +
Sbjct: 1211 DASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAE 1270
Query: 203 SKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVS-LTTQLEDTKRLA 379
E + + + L+ KK L DL +L+EAE + K ++ L ++ + +
Sbjct: 1271 ELKKEQDTSAH-LERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEV 1329
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEG 559
+ E + A + R E + + Q EE+ + LQ + K A+ + ++ + E
Sbjct: 1330 ENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEAE 1389
Query: 560 VARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEV 697
+ L + RKLQ L EAEE + +V L + + T++
Sbjct: 1390 EQSNANLSKF-RKLQHELEEAEERADIAESQVNKLRVKSREVHTKI 1434
Score = 52.8 bits (121), Expect = 1e-06
Identities = 42/178 (23%), Positives = 81/178 (45%), Gaps = 2/178 (1%)
Frame = +2
Query: 29 MGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSN-EKAAQEKIVKQLQHQLNEVQS 205
M E+L + A E+ + V DL+ LD +K +++L+ ++ E++
Sbjct: 1268 MAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEG 1327
Query: 206 KADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADE 385
+ + + + +K +L Q EE V +L + L +++ KR A+E
Sbjct: 1328 EVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEE 1387
Query: 386 EARERATLLGKFRNLEHDLDNIREQVEEEAEGKADL-QRQLSKANAEAQLWRSKYESE 556
+ L KFR L+H+L EEAE +AD+ + Q++K +++ +K +E
Sbjct: 1388 AEEQSNANLSKFRKLQHEL--------EEAEERADIAESQVNKLRVKSREVHTKISAE 1437
Score = 46.8 bits (106), Expect = 9e-05
Identities = 53/217 (24%), Positives = 100/217 (46%), Gaps = 10/217 (4%)
Frame = +2
Query: 104 VNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLND-----LDAAKKK--L 262
++D G + L + A E+ LQ ++ E+ + ++ R+ LDA+++ L
Sbjct: 1160 LDDALRGQEDLKEQLAIVERRANLLQAEIEELWATLEQTERSRKIAEQELLDASERVQLL 1219
Query: 263 SIENSDLLRQLEEAESQVSQL-SKIK--VSLTTQLEDTKRLADEEARERATLLGKFRNLE 433
+N+ L+ ++ E+ VSQL S+++ + + E+ + A +A A L K ++
Sbjct: 1220 HTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTS 1279
Query: 434 HDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARL 613
L+ +++ +E+ + DLQ +L +A A K + AR ELE Q R
Sbjct: 1280 AHLERMKKNLEQTVK---DLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRN 1336
Query: 614 AEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
AEA + + ++V L + V LQ VD+
Sbjct: 1337 AEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDK 1373
>AB023217-1|BAA76844.2| 1956|Homo sapiens KIAA1000 protein protein.
Length = 1956
Score = 164 bits (399), Expect = 3e-40
Identities = 84/228 (36%), Positives = 139/228 (60%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
++++ Q++ L ++K K EK ++ EV+DL ++ ++ KA EK+ + +L+E
Sbjct: 1222 LAELEGQVENLQQVKQKLEKDKSDLQLEVDDLLTRVEQMTRAKANAEKLCTLYEERLHEA 1281
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
+K D+ + NDL A K KL E+ + LR+LEE E+ ++QLS+ K + T Q+ED +
Sbjct: 1282 TAKLDKVTQLANDLAAQKTKLWSESGEFLRRLEEKEALINQLSREKSNFTRQIEDLRGQL 1341
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEG 559
++E + ++ L + + D D +REQ EEE E KA+L R LSK NAE WR KYE+
Sbjct: 1342 EKETKSQSALAHALQKAQRDCDLLREQYEEEQEVKAELHRTLSKVNAEMVQWRMKYENNV 1401
Query: 560 VARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVED 703
+ R+E+LE+AK++L RL EA E + N + +LE+ + +L E+ D
Sbjct: 1402 IQRTEDLEDAKKELAIRLQEAAEAMGVANARNASLERARHQLQLELGD 1449
Score = 71.7 bits (168), Expect = 3e-12
Identities = 63/247 (25%), Positives = 113/247 (45%), Gaps = 6/247 (2%)
Frame = +2
Query: 2 NSAGRFVSDMGEQ-LDQLNKLKAKAE---KXRAQYFSEVNDLRAGLDHLSNEKAAQEKIV 169
N A + V + +Q LD L+ + K K + +V++L L+ + E+ +
Sbjct: 1015 NRAAKVVQEAHQQTLDDLHMEEEKLSSLSKANLKLEQQVDELEGALEQERKARMNCEREL 1074
Query: 170 KQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLT 349
+L+ L + + + L +K +E S + ++E + V+QL K L
Sbjct: 1075 HKLEGNLKLNRESMENLESSQRHLAEELRKKELELSQMNSKVENEKGLVAQLQKTVKELQ 1134
Query: 350 TQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQ 529
TQ++D K + E RA + + +L DL ++ E++EE G + Q +++K E +
Sbjct: 1135 TQIKDLKEKLEAERTTRAKMERERADLTQDLADLNERLEEVG-GSSLAQLEITKKQ-ETK 1192
Query: 530 LWRSKYESEGVARSEELEEA--KRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVED 703
+ + + E E A K++ LAE E +E+L Q LEK K L EV+D
Sbjct: 1193 IQKLHRDMEEATLHFETTSASLKKRHADSLAELEGQVENLQQVKQKLEKDKSDLQLEVDD 1252
Query: 704 LQLEVDR 724
L V++
Sbjct: 1253 LLTRVEQ 1259
Score = 62.1 bits (144), Expect = 2e-09
Identities = 52/229 (22%), Positives = 105/229 (45%), Gaps = 8/229 (3%)
Frame = +2
Query: 47 QLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANR 226
+L++ + E R + ++ L++ LD + + ++ K+++ LNE++ + ANR
Sbjct: 1597 KLSEKDEEIENFRRKQQCTIDSLQSSLDSEAKSRIEVTRLKKKMEEDLNEMELQLSCANR 1656
Query: 227 TLNDLDAAKKKLSIENSDLLRQLEEA-------ESQVSQLSKIKVSLTTQLEDTKRLADE 385
+++ + +L I+ DL QL+++ + QV+ + L ++LED + L ++
Sbjct: 1657 QVSEATKSLGQLQIQIKDLQMQLDDSTQLNSDLKEQVAVAERRNSLLQSELEDLRSLQEQ 1716
Query: 386 EARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVA 565
R R R E +L E++ L Q K EA + R + E+E V
Sbjct: 1717 TERGR-------RLSEEELLEATERINLFYTQNTSLLSQ--KKKLEADVARMQKEAEEVV 1767
Query: 566 RS-EELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQ 709
+ + EE +K A E ++ + LE+T++ + + DLQ
Sbjct: 1768 QECQNAEEKAKKAAIEAANLSEELKKKQDTIAHLERTRENMEQTITDLQ 1816
Score = 61.3 bits (142), Expect = 4e-09
Identities = 58/254 (22%), Positives = 121/254 (47%), Gaps = 21/254 (8%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDH-------LSNEKAAQEKIVKQL 178
+++M QL N+ ++A K Q ++ DL+ LD L + A E+ L
Sbjct: 1644 LNEMELQLSCANRQVSEATKSLGQLQIQIKDLQMQLDDSTQLNSDLKEQVAVAERRNSLL 1703
Query: 179 QHQLNEVQSKADEANR----TLNDLDAAKKKLSI---ENSDLLRQLEEAESQVSQLSKIK 337
Q +L +++S ++ R + +L A +++++ +N+ LL Q ++ E+ V+++ K
Sbjct: 1704 QSELEDLRSLQEQTERGRRLSEEELLEATERINLFYTQNTSLLSQKKKLEADVARMQKEA 1763
Query: 338 VSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKAN 517
+ + ++ + A + A E A L + + + + ++ E + DLQ++L++A
Sbjct: 1764 EEVVQECQNAEEKAKKAAIEAANLSEELKKKQDTIAHLERTRENMEQTITDLQKRLAEAE 1823
Query: 518 AEAQLWRSKYESEGVARSEELE-----EAKRKLQAR--LAEAEETIESLNQKVVALEKTK 676
A + K + +R ELE E +R +A+ E I+ L + +K
Sbjct: 1824 QMALMGSRKQIQKLESRVRELEGELEGEIRRSAEAQRGARRLERCIKELTYQAEEDKKNL 1883
Query: 677 QRLATEVEDLQLEV 718
R+ T+++ LQL+V
Sbjct: 1884 SRMQTQMDKLQLKV 1897
Score = 60.9 bits (141), Expect = 5e-09
Identities = 62/246 (25%), Positives = 119/246 (48%), Gaps = 14/246 (5%)
Frame = +2
Query: 26 DMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQS 205
++G+ L L K+++ A + + L++G L++ K E+ L EVQ+
Sbjct: 1446 ELGDALSDLGKVRSAAARL------DQKQLQSG-KALADWKQKHEESQALLDASQKEVQA 1498
Query: 206 KADEANRTLNDLDAA---KKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRL 376
+ E + N + + ++ L EN +L ++ +QV + +K T++E K+L
Sbjct: 1499 LSTELLKLKNTYEESIVGQETLRRENKNLQEEISNLTNQVREGTKN----LTEMEKVKKL 1554
Query: 377 ADEEARE-RATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYES 553
+EE E + TL LE + I E E KA+L+R+LS+ + E + +R K +
Sbjct: 1555 IEEEKTEVQVTLEETEGALERNESKILHFQLELLEAKAELERKLSEKDEEIENFRRKQQC 1614
Query: 554 ---------EGVARSE-ELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVED 703
+ A+S E+ K+K++ L E E + N++V K+ +L +++D
Sbjct: 1615 TIDSLQSSLDSEAKSRIEVTRLKKKMEEDLNEMELQLSCANRQVSEATKSLGQLQIQIKD 1674
Query: 704 LQLEVD 721
LQ+++D
Sbjct: 1675 LQMQLD 1680
Score = 51.6 bits (118), Expect = 3e-06
Identities = 46/231 (19%), Positives = 97/231 (41%), Gaps = 1/231 (0%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQ-EKIVKQLQHQLNEVQSKA 211
EQ ++ ++KA+ + ++ +E+ R ++ ++ E K+L +L E
Sbjct: 1367 EQYEEEQEVKAELHRTLSKVNAEMVQWRMKYENNVIQRTEDLEDAKKELAIRLQEAAEAM 1426
Query: 212 DEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEA 391
AN L+ A+ +L +E D L L + S ++L + ++ L D K+ +E
Sbjct: 1427 GVANARNASLERARHQLQLELGDALSDLGKVRSAAARLDQKQLQSGKALADWKQKHEESQ 1486
Query: 392 RERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARS 571
+ + L +L ++ EE G+ L+R+ E ++ EG
Sbjct: 1487 ALLDASQKEVQALSTELLKLKNTYEESIVGQETLRRENKNLQEEISNLTNQVR-EGTKNL 1545
Query: 572 EELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
E+E+ K+ ++ E + T+E + E E+ + + E++R
Sbjct: 1546 TEMEKVKKLIEEEKTEVQVTLEETEGALERNESKILHFQLELLEAKAELER 1596
>X03741-1|CAA27381.1| 635|Homo sapiens protein ( Human cardiac mRNA
for myosin heavy chain light meromyosin region. ).
Length = 635
Score = 135 bits (326), Expect = 2e-31
Identities = 65/124 (52%), Positives = 86/124 (69%)
Frame = +2
Query: 353 QLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQL 532
QL D KR +EE + + L ++ HD D +REQ EEE E KA LQ LSKAN+E
Sbjct: 11 QLGDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKARLQGDLSKANSEVAQ 70
Query: 533 WRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQL 712
WR+KYE++ + R+EELEEAK+KL RL EAEE +E++N K +LEKTK RL E+EDL +
Sbjct: 71 WRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMV 130
Query: 713 EVDR 724
+V+R
Sbjct: 131 DVER 134
Score = 73.7 bits (173), Expect = 7e-13
Identities = 51/237 (21%), Positives = 109/237 (45%), Gaps = 1/237 (0%)
Frame = +2
Query: 14 RFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLN 193
R V + LD + + +A + + + ++N++ L H + A +K VK LQ L
Sbjct: 292 RVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLK 351
Query: 194 EVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKR 373
+ Q + D+A R +DL + N+ L +LEE + V Q + + +L +T
Sbjct: 352 DTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSE 411
Query: 374 LADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYES 553
+ +L+ + + ++ DL ++ +VEE + + + + KA +A + + +
Sbjct: 412 RVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKK 471
Query: 554 EGVARSEELEEAKRKLQARLAEAEETIESLNQ-KVVALEKTKQRLATEVEDLQLEVD 721
E S LE K+ ++ + + + ++ Q + +K Q+L V +L+ E++
Sbjct: 472 E-QDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELE 527
Score = 61.7 bits (143), Expect = 3e-09
Identities = 46/235 (19%), Positives = 111/235 (47%), Gaps = 1/235 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+SD+ EQL K + EK R Q +E +L++ L+ +E + + Q + N++
Sbjct: 209 ISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQI 268
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQV-SQLSKIKVSLTTQLEDTKRL 376
+++ + + ++ K+ + D L+ +AE++ ++ ++K + L + +
Sbjct: 269 KAEIERKRQEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQ 328
Query: 377 ADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESE 556
R A + ++L+ L + + Q+++ DL+ ++ L +++ E E
Sbjct: 329 LSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELE-E 387
Query: 557 GVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
A E+ E +++ + L E E ++ L+ + +L K+++ ++ LQ EV+
Sbjct: 388 LRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVE 442
Score = 60.9 bits (141), Expect = 5e-09
Identities = 50/231 (21%), Positives = 101/231 (43%), Gaps = 1/231 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+ D+ QL++ K K + + LR + + KA + + + ++ +
Sbjct: 12 LGDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKARLQGDLSKANSEVAQW 71
Query: 200 QSKAD-EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRL 376
++K + +A + +L+ AKKKL+ + +E ++ S L K K L ++ED
Sbjct: 72 RTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVD 131
Query: 377 ADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESE 556
+ A L K RN + L +++ EE Q++ + E ++ YE E
Sbjct: 132 VERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYE-E 190
Query: 557 GVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQ 709
+ E + + LQ +++ E + S + + LEK +++L E +LQ
Sbjct: 191 SLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQ 241
Score = 50.0 bits (114), Expect = 9e-06
Identities = 39/169 (23%), Positives = 80/169 (47%), Gaps = 2/169 (1%)
Frame = +2
Query: 29 MGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSN-EKAAQEKIVKQLQHQLNEVQS 205
M E+L + A E+ + + DL+ LD +K +++L+ ++ E+++
Sbjct: 465 MAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEN 524
Query: 206 KADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADE 385
+ + + + +K +L Q EE + +L + L +++ KR A+E
Sbjct: 525 ELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEE 584
Query: 386 EARERATLLGKFRNLEHDLDNIREQVEEEAEGKADL-QRQLSKANAEAQ 529
+ T L KFR ++H+LD EAE +AD+ + Q++K A+++
Sbjct: 585 AEEQANTNLSKFRKVQHELD--------EAEERADIAESQVNKLRAKSR 625
Score = 48.0 bits (109), Expect = 4e-05
Identities = 61/254 (24%), Positives = 117/254 (46%), Gaps = 21/254 (8%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+++M QL N++ A+A+K S + D + LD ++ + ++ + N +
Sbjct: 322 LNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLL 381
Query: 200 QSKADEANRTLNDLDAAKKKLS---IENSDLLRQLEEAE-SQVSQLSKIKVSLT---TQL 358
Q++ +E + + ++K IE S+ ++ L S ++Q K+ L+ T++
Sbjct: 382 QAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEV 441
Query: 359 EDTK---RLADEEARERAT---LLGKFRNLEHDLDNIREQVEEEAEGKA-DLQRQLSKAN 517
E+ R A+E+A++ T ++ + E D E++++ E DLQ +L +A
Sbjct: 442 EEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAE 501
Query: 518 AEAQLWRSKYESEGVARSEELE---EAKRKLQAR----LAEAEETIESLNQKVVALEKTK 676
A K + AR ELE EA++K A + ++E I+ L + K
Sbjct: 502 QIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNL 561
Query: 677 QRLATEVEDLQLEV 718
RL V+ LQL+V
Sbjct: 562 LRLQDLVDKLQLKV 575
Score = 47.2 bits (107), Expect = 7e-05
Identities = 48/231 (20%), Positives = 102/231 (44%), Gaps = 5/231 (2%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD 214
E L+ L K + + + E++DL L EK+ KQL+ + E+QS +
Sbjct: 190 ESLEHLETFKRENKNLQ----EEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALE 245
Query: 215 EANRTLNDLDAAKKKLSIENSDLLRQLE-EAESQVSQLSKIKVSLTTQLEDTKRLADEEA 391
EA +L + + +E + + ++E + + + ++ + K + ++ + D E
Sbjct: 246 EAEASLEHEEGKILRAQLEFNQIKAEIERKRQEKDEEMEQAKRNHLRVVDSLQTSLDAET 305
Query: 392 RERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARS 571
R R L + +E DL+ + Q+ A+ Q+Q+ + + + + + + V +
Sbjct: 306 RSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLD-DAVRAN 364
Query: 572 EELEE----AKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQL 712
++L+E +R+ AE EE + Q + + +Q L E +QL
Sbjct: 365 DDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQL 415
>X69292-1|CAA49154.1| 881|Homo sapiens smooth muscle mysosin heavy
chain protein.
Length = 881
Score = 129 bits (311), Expect = 1e-29
Identities = 79/235 (33%), Positives = 126/235 (53%), Gaps = 1/235 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
V ++ EQL+Q + KA +K + E DL L L K E K+L+ Q+ E+
Sbjct: 114 VEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQEL 173
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
QSK + R +L+ KL E + L EAE + +L+K SL++QL+DT+ L
Sbjct: 174 QSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELL 233
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEG 559
EE R++ + K R LE + +++++Q++EE E K +L+R +S N QL SK + +
Sbjct: 234 QEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLN--IQLSDSKKKLQD 291
Query: 560 VARS-EELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
A + E LEE K++ Q + + E LEKTK RL E++DL +++D
Sbjct: 292 FASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLD 346
Score = 77.8 bits (183), Expect = 4e-14
Identities = 62/239 (25%), Positives = 114/239 (47%), Gaps = 5/239 (2%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDH----LSNEKAAQEKIVKQLQHQ 187
+ ++ +Q ++ K EK + + E++DL LD+ +SN + Q K + L +
Sbjct: 310 IENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEE 369
Query: 188 LNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDT 367
N ADE +R +A ++ + L R LEEA +L + L ++ED
Sbjct: 370 KNISSKYADERDRA----EAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDL 425
Query: 368 KRLADEEARERATLLGKFRNLEHDLDNIREQVEE-EAEGKADLQRQLSKANAEAQLWRSK 544
D+ + L R LE ++ ++ Q+EE E E +A +L + Q + +
Sbjct: 426 VSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKL-RLEVNMQALKGQ 484
Query: 545 YESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
+E + AR E+ EE +R+LQ +L E E +E ++ K++L +++DL+L+ D
Sbjct: 485 FERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQAD 543
Score = 68.5 bits (160), Expect = 3e-11
Identities = 53/212 (25%), Positives = 101/212 (47%), Gaps = 1/212 (0%)
Frame = +2
Query: 62 KAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDL 241
K + E AQ E+ + + ++ +S+ K +Q + NE+ ++ A +
Sbjct: 640 KRRLEARIAQLEEELEEEQGNMEAMSDRV---RKATQQAEQLSNELATERSTAQKN---- 692
Query: 242 DAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVS-LTTQLEDTKRLADEEARERATLLGK 418
++++++L +N +L +L E E V K ++ L ++ + ++EARE+
Sbjct: 693 ESSRQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKS 752
Query: 419 FRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRK 598
+ + L I QVE+E + + Q K NA + + + E E S+ + +RK
Sbjct: 753 LKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLE-EAEEESQRINANRRK 811
Query: 599 LQARLAEAEETIESLNQKVVALEKTKQRLATE 694
LQ L EA E+ E++ ++V AL K+K R E
Sbjct: 812 LQRELDEATESNEAMGREVNAL-KSKLRRGNE 842
Score = 63.7 bits (148), Expect = 7e-10
Identities = 59/241 (24%), Positives = 108/241 (44%), Gaps = 8/241 (3%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDH-LSNEKAAQEKIVKQLQHQLNE 196
+ +M QL++L E + + + L+ + L E+ +QLQ QL+E
Sbjct: 450 MEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHE 509
Query: 197 VQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEA----ESQVSQLSKIKVSL---TTQ 355
+++ ++ + AAKKKL + DL Q + A E + QL K++ + +
Sbjct: 510 YETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRE 569
Query: 356 LEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLW 535
LED + DE K ++LE DL ++E + A +A Q L K +L
Sbjct: 570 LEDARASRDEIFATAKENEKKAKSLEADLMQLQEDL--AAAERARKQADLEKEELAEEL- 626
Query: 536 RSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLE 715
+ ++ L++ KR+L+AR+A+ EE +E + A+ ++ + E L E
Sbjct: 627 -----ASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNE 681
Query: 716 V 718
+
Sbjct: 682 L 682
Score = 56.0 bits (129), Expect = 1e-07
Identities = 50/235 (21%), Positives = 106/235 (45%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+SD+ E LD + KAEK + E+ L+ L+ + A Q+++ + + ++ +
Sbjct: 29 ISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVL 88
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
+ DE R+ +A +++ +++ + +L E Q+ Q + K +L + ++
Sbjct: 89 KKALDEETRS---HEAQVQEMRQKHAQAVEELTE---QLEQFKRAKANLDKNKQTLEKEN 142
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEG 559
+ A E L + +EH + QV+E +D +R ++ N + +++ ES
Sbjct: 143 ADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESV- 201
Query: 560 VARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
E E KL +A ++ + + E+T+Q+L + QLE +R
Sbjct: 202 TGMLNEAEGKAIKLAKDVASLSSQLQDTQE--LLQEETRQKLNVSTKLRQLEEER 254
Score = 48.8 bits (111), Expect = 2e-05
Identities = 49/229 (21%), Positives = 100/229 (43%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD 214
E L + + +A+ + + E+ +G + L +EK E + QL+ +L E Q +
Sbjct: 603 EDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNME 662
Query: 215 EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEAR 394
+ + ++LS E + ++ ES QL + L ++L + + +++
Sbjct: 663 AMSDRVRKATQQAEQLSNELATERSTAQKNESSRQQLERQNKELRSKLHEMEGAV--KSK 720
Query: 395 ERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSE 574
++T+ LE + + EQVE+EA K + L + + + + + E E +E
Sbjct: 721 FKSTIAA----LEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDER-KMAE 775
Query: 575 ELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
+ +E K AR+ + + +E E+ QR+ LQ E+D
Sbjct: 776 QYKEQAEKGNARVKQLKRQLEEA-------EEESQRINANRRKLQRELD 817
Score = 43.6 bits (98), Expect = 8e-04
Identities = 28/122 (22%), Positives = 55/122 (45%)
Frame = +2
Query: 59 LKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLND 238
+K+K + A +++ L ++ + EK A K +KQ +L E+ + ++ +
Sbjct: 717 VKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQ 776
Query: 239 LDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGK 418
+K + L RQLEEAE + +++ + L +L++ + RE L K
Sbjct: 777 YKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSK 836
Query: 419 FR 424
R
Sbjct: 837 LR 838
Score = 31.1 bits (67), Expect = 4.7
Identities = 30/135 (22%), Positives = 57/135 (42%), Gaps = 14/135 (10%)
Frame = +2
Query: 353 QLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLS-------- 508
+L+D + ++ L G +L+ DLD+ R + + K DL +L
Sbjct: 7 RLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELED 66
Query: 509 --KANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAE----ETIESLNQKVVALEK 670
+ A Q R+K E E + L+E R +A++ E + +E L +++ ++
Sbjct: 67 TLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKR 126
Query: 671 TKQRLATEVEDLQLE 715
K L + L+ E
Sbjct: 127 AKANLDKNKQTLEKE 141
>D10667-1|BAA36971.1| 1052|Homo sapiens smooth muscle myosin heavy
chain protein.
Length = 1052
Score = 129 bits (311), Expect = 1e-29
Identities = 79/235 (33%), Positives = 126/235 (53%), Gaps = 1/235 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
V ++ EQL+Q + KA +K + E DL L L K E K+L+ Q+ E+
Sbjct: 319 VEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQEL 378
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
QSK + R +L+ KL E + L EAE + +L+K SL++QL+DT+ L
Sbjct: 379 QSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELL 438
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEG 559
EE R++ + K R LE + +++++Q++EE E K +L+R +S N QL SK + +
Sbjct: 439 QEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLN--IQLSDSKKKLQD 496
Query: 560 VARS-EELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
A + E LEE K++ Q + + E LEKTK RL E++DL +++D
Sbjct: 497 FASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLD 551
Score = 77.8 bits (183), Expect = 4e-14
Identities = 62/239 (25%), Positives = 113/239 (47%), Gaps = 5/239 (2%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDH----LSNEKAAQEKIVKQLQHQ 187
+ ++ +Q ++ K EK + + E++DL LD+ +SN + Q K + L +
Sbjct: 515 IENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEE 574
Query: 188 LNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDT 367
N ADE +R +A ++ + L R LEEA +L + L ++ED
Sbjct: 575 KNISSKYADERDRA----EAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDL 630
Query: 368 KRLADEEARERATLLGKFRNLEHDLDNIREQVEE-EAEGKADLQRQLSKANAEAQLWRSK 544
D+ + L R LE ++ ++ Q+EE E E +A +L + Q + +
Sbjct: 631 VSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQASEDAKL-RLEVNMQALKGQ 689
Query: 545 YESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
+E + AR E+ EE +R+LQ +L E E +E + K++L +++DL+L+ D
Sbjct: 690 FERDLQARDEQNEEKRRQLQRQLHEYETELEDERNERALAAAAKKKLEGDLKDLELQAD 748
Score = 71.3 bits (167), Expect = 4e-12
Identities = 58/232 (25%), Positives = 110/232 (47%), Gaps = 3/232 (1%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFS---EVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQS 205
E+ D+ +L+A+ +K Q ++ + A L EK E +K+L+ ++ +
Sbjct: 47 EEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVM-- 104
Query: 206 KADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADE 385
D+ N N L +K L SDL L E E + L+K+K + + + + +
Sbjct: 105 --DDQN---NKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKK 159
Query: 386 EARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVA 565
E + R L R LE D + EQ+ + A+L+ QL+K E Q ++ + E
Sbjct: 160 EEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQ 219
Query: 566 RSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
++ L++ R+L+ +++ +E ++S EK K+ L E+E L+ E++
Sbjct: 220 KNNALKKI-RELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELE 270
Score = 68.5 bits (160), Expect = 3e-11
Identities = 53/208 (25%), Positives = 100/208 (48%), Gaps = 1/208 (0%)
Frame = +2
Query: 62 KAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDL 241
K + E AQ E+ + + ++ +S+ K +Q + NE+ ++ A +
Sbjct: 845 KRRLEARIAQLEEELEEEQGNMEAMSDRV---RKATQQAEQLSNELATERSTAQKN---- 897
Query: 242 DAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVS-LTTQLEDTKRLADEEARERATLLGK 418
++A+++L +N +L +L E E V K ++ L ++ + ++EARE+
Sbjct: 898 ESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKS 957
Query: 419 FRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRK 598
+ + L I QVE+E + + Q K NA + + + E E S+ + +RK
Sbjct: 958 LKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLE-EAEEESQRINANRRK 1016
Query: 599 LQARLAEAEETIESLNQKVVALEKTKQR 682
LQ L EA E+ E++ ++V AL K+K R
Sbjct: 1017 LQRELDEATESNEAMGREVNAL-KSKLR 1043
Score = 63.3 bits (147), Expect = 9e-10
Identities = 59/241 (24%), Positives = 108/241 (44%), Gaps = 8/241 (3%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDH-LSNEKAAQEKIVKQLQHQLNE 196
+ +M QL++L +E + + + L+ + L E+ +QLQ QL+E
Sbjct: 655 MEEMKTQLEELEDELQASEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHE 714
Query: 197 VQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEA----ESQVSQLSKIKVSL---TTQ 355
+++ ++ AAKKKL + DL Q + A E + QL K++ + +
Sbjct: 715 YETELEDERNERALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRE 774
Query: 356 LEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLW 535
LED + DE K ++LE DL ++E + A +A Q L K +L
Sbjct: 775 LEDARASRDEIFATAKENEKKAKSLEADLMQLQEDL--AAAERARKQADLEKEELAEEL- 831
Query: 536 RSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLE 715
+ ++ L++ KR+L+AR+A+ EE +E + A+ ++ + E L E
Sbjct: 832 -----ASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNE 886
Query: 716 V 718
+
Sbjct: 887 L 887
Score = 62.1 bits (144), Expect = 2e-09
Identities = 52/188 (27%), Positives = 95/188 (50%), Gaps = 3/188 (1%)
Frame = +2
Query: 170 KQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLT 349
++L+ L+E++++ +E L A +KK++ + DL QLEE E+ +L KV+
Sbjct: 32 QELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAE 91
Query: 350 TQLEDTKRLADE--EARERATLLGKFRN-LEHDLDNIREQVEEEAEGKADLQRQLSKANA 520
++ K+L DE ++ L K R LE + ++ + EE E +L + +K +
Sbjct: 92 AKI---KKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHES 148
Query: 521 EAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVE 700
+ + E +R +ELE+ KRKL+ ++ E I L ++ L K +LA + E
Sbjct: 149 MISELEVRLKKEEKSR-QELEKLKRKLEGDASDFHEQIADLQAQIAEL---KMQLAKKEE 204
Query: 701 DLQLEVDR 724
+LQ + R
Sbjct: 205 ELQAALAR 212
Score = 56.0 bits (129), Expect = 1e-07
Identities = 53/245 (21%), Positives = 105/245 (42%), Gaps = 21/245 (8%)
Frame = +2
Query: 44 DQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEAN 223
DQ NKL K R ++DL L + K+ + + ++E++ + +
Sbjct: 106 DQNNKLS----KERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEE 161
Query: 224 RTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERA 403
++ +L+ K+KL + SD Q+ + ++Q+++L +L+ D+E ++
Sbjct: 162 KSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKN 221
Query: 404 TLLGKFR-------NLEHDLDNIREQVEEEAEGKADLQRQLS----------KANAEAQL 532
L K R +L+ DLD+ R + + K DL +L + A Q
Sbjct: 222 NALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQE 281
Query: 533 WRSKYESEGVARSEELEEAKRKLQARLAEAE----ETIESLNQKVVALEKTKQRLATEVE 700
R+K E E + L+E R +A++ E + +E L +++ ++ K L +
Sbjct: 282 LRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQ 341
Query: 701 DLQLE 715
L+ E
Sbjct: 342 TLEKE 346
Score = 56.0 bits (129), Expect = 1e-07
Identities = 50/235 (21%), Positives = 106/235 (45%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+SD+ E LD + KAEK + E+ L+ L+ + A Q+++ + + ++ +
Sbjct: 234 ISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVL 293
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
+ DE R+ +A +++ +++ + +L E Q+ Q + K +L + ++
Sbjct: 294 KKALDEETRS---HEAQVQEMRQKHAQAVEELTE---QLEQFKRAKANLDKNKQTLEKEN 347
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEG 559
+ A E L + +EH + QV+E +D +R ++ N + +++ ES
Sbjct: 348 ADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESV- 406
Query: 560 VARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
E E KL +A ++ + + E+T+Q+L + QLE +R
Sbjct: 407 TGMLNEAEGKAIKLAKDVASLSSQLQDTQE--LLQEETRQKLNVSTKLRQLEEER 459
Score = 48.4 bits (110), Expect = 3e-05
Identities = 49/229 (21%), Positives = 100/229 (43%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD 214
E L + + +A+ + + E+ +G + L +EK E + QL+ +L E Q +
Sbjct: 808 EDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNME 867
Query: 215 EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEAR 394
+ + ++LS E + ++ ES QL + L ++L + + +++
Sbjct: 868 AMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAV--KSK 925
Query: 395 ERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSE 574
++T+ LE + + EQVE+EA K + L + + + + + E E +E
Sbjct: 926 FKSTIAA----LEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDER-KMAE 980
Query: 575 ELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
+ +E K AR+ + + +E E+ QR+ LQ E+D
Sbjct: 981 QYKEQAEKGNARVKQLKRQLEEA-------EEESQRINANRRKLQRELD 1022
Score = 43.6 bits (98), Expect = 8e-04
Identities = 28/122 (22%), Positives = 55/122 (45%)
Frame = +2
Query: 59 LKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLND 238
+K+K + A +++ L ++ + EK A K +KQ +L E+ + ++ +
Sbjct: 922 VKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQ 981
Query: 239 LDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGK 418
+K + L RQLEEAE + +++ + L +L++ + RE L K
Sbjct: 982 YKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSK 1041
Query: 419 FR 424
R
Sbjct: 1042 LR 1043
Score = 43.2 bits (97), Expect = 0.001
Identities = 41/183 (22%), Positives = 80/183 (43%), Gaps = 2/183 (1%)
Frame = +2
Query: 176 LQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQ 355
LQ QL EA L A K++L ++ +LEE E + QL + + Q
Sbjct: 6 LQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQ 65
Query: 356 LEDTKRLADEEARERATLLGKFRNLEHDLDNIREQ--VEEEAEGKADLQRQLSKANAEAQ 529
+ D + +EE R L + E + + ++ V ++ K +R+L + +
Sbjct: 66 MLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERI-SD 124
Query: 530 LWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQ 709
L + E E +++ L + K K ++ ++E E ++ + LEK K++L + D
Sbjct: 125 LTTNLAEEE--EKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFH 182
Query: 710 LEV 718
++
Sbjct: 183 EQI 185
>BC104906-1|AAI04907.1| 1938|Homo sapiens myosin, heavy chain 11,
smooth muscle protein.
Length = 1938
Score = 129 bits (311), Expect = 1e-29
Identities = 79/235 (33%), Positives = 126/235 (53%), Gaps = 1/235 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
V ++ EQL+Q + KA +K + E DL L L K E K+L+ Q+ E+
Sbjct: 1205 VEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQEL 1264
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
QSK + R +L+ KL E + L EAE + +L+K SL++QL+DT+ L
Sbjct: 1265 QSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELL 1324
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEG 559
EE R++ + K R LE + +++++Q++EE E K +L+R +S N QL SK + +
Sbjct: 1325 QEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLN--IQLSDSKKKLQD 1382
Query: 560 VARS-EELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
A + E LEE K++ Q + + E LEKTK RL E++DL +++D
Sbjct: 1383 FASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLD 1437
Score = 77.8 bits (183), Expect = 4e-14
Identities = 62/239 (25%), Positives = 114/239 (47%), Gaps = 5/239 (2%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDH----LSNEKAAQEKIVKQLQHQ 187
+ ++ +Q ++ K EK + + E++DL LD+ +SN + Q K + L +
Sbjct: 1401 IENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEE 1460
Query: 188 LNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDT 367
N ADE +R +A ++ + L R LEEA +L + L ++ED
Sbjct: 1461 KNISSKYADERDRA----EAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDL 1516
Query: 368 KRLADEEARERATLLGKFRNLEHDLDNIREQVEE-EAEGKADLQRQLSKANAEAQLWRSK 544
D+ + L R LE ++ ++ Q+EE E E +A +L + Q + +
Sbjct: 1517 VSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKL-RLEVNMQALKGQ 1575
Query: 545 YESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
+E + AR E+ EE +R+LQ +L E E +E ++ K++L +++DL+L+ D
Sbjct: 1576 FERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQAD 1634
Score = 71.3 bits (167), Expect = 4e-12
Identities = 58/232 (25%), Positives = 110/232 (47%), Gaps = 3/232 (1%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFS---EVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQS 205
E+ D+ +L+A+ +K Q ++ + A L EK E +K+L+ ++ +
Sbjct: 933 EEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVM-- 990
Query: 206 KADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADE 385
D+ N N L +K L SDL L E E + L+K+K + + + + +
Sbjct: 991 --DDQN---NKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKK 1045
Query: 386 EARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVA 565
E + R L R LE D + EQ+ + A+L+ QL+K E Q ++ + E
Sbjct: 1046 EEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQ 1105
Query: 566 RSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
++ L++ R+L+ +++ +E ++S EK K+ L E+E L+ E++
Sbjct: 1106 KNNALKKI-RELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELE 1156
Score = 68.5 bits (160), Expect = 3e-11
Identities = 53/208 (25%), Positives = 100/208 (48%), Gaps = 1/208 (0%)
Frame = +2
Query: 62 KAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDL 241
K + E AQ E+ + + ++ +S+ K +Q + NE+ ++ A +
Sbjct: 1731 KRRLEARIAQLEEELEEEQGNMEAMSDRV---RKATQQAEQLSNELATERSTAQKN---- 1783
Query: 242 DAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVS-LTTQLEDTKRLADEEARERATLLGK 418
++A+++L +N +L +L E E V K ++ L ++ + ++EARE+
Sbjct: 1784 ESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKS 1843
Query: 419 FRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRK 598
+ + L I QVE+E + + Q K NA + + + E E S+ + +RK
Sbjct: 1844 LKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLE-EAEEESQRINANRRK 1902
Query: 599 LQARLAEAEETIESLNQKVVALEKTKQR 682
LQ L EA E+ E++ ++V AL K+K R
Sbjct: 1903 LQRELDEATESNEAMGREVNAL-KSKLR 1929
Score = 63.7 bits (148), Expect = 7e-10
Identities = 59/241 (24%), Positives = 108/241 (44%), Gaps = 8/241 (3%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDH-LSNEKAAQEKIVKQLQHQLNE 196
+ +M QL++L E + + + L+ + L E+ +QLQ QL+E
Sbjct: 1541 MEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHE 1600
Query: 197 VQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEA----ESQVSQLSKIKVSL---TTQ 355
+++ ++ + AAKKKL + DL Q + A E + QL K++ + +
Sbjct: 1601 YETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRE 1660
Query: 356 LEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLW 535
LED + DE K ++LE DL ++E + A +A Q L K +L
Sbjct: 1661 LEDARASRDEIFATAKENEKKAKSLEADLMQLQEDL--AAAERARKQADLEKEELAEEL- 1717
Query: 536 RSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLE 715
+ ++ L++ KR+L+AR+A+ EE +E + A+ ++ + E L E
Sbjct: 1718 -----ASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNE 1772
Query: 716 V 718
+
Sbjct: 1773 L 1773
Score = 62.9 bits (146), Expect = 1e-09
Identities = 58/233 (24%), Positives = 113/233 (48%), Gaps = 3/233 (1%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD 214
++L+Q + + + + +L A + + AA+++ +L+ L+E++++ +
Sbjct: 876 KELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQ---ELEEILHEMEARLE 932
Query: 215 EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADE--E 388
E L A +KK++ + DL QLEE E+ +L KV+ ++ K+L DE
Sbjct: 933 EEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKI---KKLEDEILV 989
Query: 389 ARERATLLGKFRN-LEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVA 565
++ L K R LE + ++ + EE E +L + +K + + + E +
Sbjct: 990 MDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKS 1049
Query: 566 RSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
R +ELE+ KRKL+ ++ E I L ++ L K +LA + E+LQ + R
Sbjct: 1050 R-QELEKLKRKLEGDASDFHEQIADLQAQIAEL---KMQLAKKEEELQAALAR 1098
Score = 56.0 bits (129), Expect = 1e-07
Identities = 53/245 (21%), Positives = 105/245 (42%), Gaps = 21/245 (8%)
Frame = +2
Query: 44 DQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEAN 223
DQ NKL K R ++DL L + K+ + + ++E++ + +
Sbjct: 992 DQNNKLS----KERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEE 1047
Query: 224 RTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERA 403
++ +L+ K+KL + SD Q+ + ++Q+++L +L+ D+E ++
Sbjct: 1048 KSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKN 1107
Query: 404 TLLGKFR-------NLEHDLDNIREQVEEEAEGKADLQRQLS----------KANAEAQL 532
L K R +L+ DLD+ R + + K DL +L + A Q
Sbjct: 1108 NALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQE 1167
Query: 533 WRSKYESEGVARSEELEEAKRKLQARLAEAE----ETIESLNQKVVALEKTKQRLATEVE 700
R+K E E + L+E R +A++ E + +E L +++ ++ K L +
Sbjct: 1168 LRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQ 1227
Query: 701 DLQLE 715
L+ E
Sbjct: 1228 TLEKE 1232
Score = 56.0 bits (129), Expect = 1e-07
Identities = 50/235 (21%), Positives = 106/235 (45%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+SD+ E LD + KAEK + E+ L+ L+ + A Q+++ + + ++ +
Sbjct: 1120 ISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVL 1179
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
+ DE R+ +A +++ +++ + +L E Q+ Q + K +L + ++
Sbjct: 1180 KKALDEETRS---HEAQVQEMRQKHAQAVEELTE---QLEQFKRAKANLDKNKQTLEKEN 1233
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEG 559
+ A E L + +EH + QV+E +D +R ++ N + +++ ES
Sbjct: 1234 ADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESV- 1292
Query: 560 VARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
E E KL +A ++ + + E+T+Q+L + QLE +R
Sbjct: 1293 TGMLNEAEGKAIKLAKDVASLSSQLQDTQE--LLQEETRQKLNVSTKLRQLEEER 1345
Score = 53.2 bits (122), Expect = 1e-06
Identities = 44/200 (22%), Positives = 95/200 (47%), Gaps = 10/200 (5%)
Frame = +2
Query: 155 QEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLE-------EAESQ 313
QE+ ++ + +L + + + +A L +L+ +L+ E + L QL+ EAE
Sbjct: 850 QEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEM 909
Query: 314 VSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADL 493
+L+ K L L + + +EE L + + + + ++ EQ+EEE + L
Sbjct: 910 RVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKL 969
Query: 494 QRQLSKANAEAQLWRSKYESEGVA---RSEELEEAKRKLQARLAEAEETIESLNQKVVAL 664
QL K AEA++ K E E + ++ +L + ++ L+ R+++ + +K L
Sbjct: 970 --QLEKVTAEAKI--KKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNL 1025
Query: 665 EKTKQRLATEVEDLQLEVDR 724
K K + + + +L++ + +
Sbjct: 1026 TKLKNKHESMISELEVRLKK 1045
Score = 48.4 bits (110), Expect = 3e-05
Identities = 49/229 (21%), Positives = 100/229 (43%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD 214
E L + + +A+ + + E+ +G + L +EK E + QL+ +L E Q +
Sbjct: 1694 EDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNME 1753
Query: 215 EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEAR 394
+ + ++LS E + ++ ES QL + L ++L + + +++
Sbjct: 1754 AMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAV--KSK 1811
Query: 395 ERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSE 574
++T+ LE + + EQVE+EA K + L + + + + + E E +E
Sbjct: 1812 FKSTIAA----LEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDER-KMAE 1866
Query: 575 ELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
+ +E K AR+ + + +E E+ QR+ LQ E+D
Sbjct: 1867 QYKEQAEKGNARVKQLKRQLEEA-------EEESQRINANRRKLQRELD 1908
Score = 43.6 bits (98), Expect = 8e-04
Identities = 28/122 (22%), Positives = 55/122 (45%)
Frame = +2
Query: 59 LKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLND 238
+K+K + A +++ L ++ + EK A K +KQ +L E+ + ++ +
Sbjct: 1808 VKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQ 1867
Query: 239 LDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGK 418
+K + L RQLEEAE + +++ + L +L++ + RE L K
Sbjct: 1868 YKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSK 1927
Query: 419 FR 424
R
Sbjct: 1928 LR 1929
>BC101677-1|AAI01678.1| 1938|Homo sapiens myosin, heavy chain 11,
smooth muscle protein.
Length = 1938
Score = 129 bits (311), Expect = 1e-29
Identities = 79/235 (33%), Positives = 126/235 (53%), Gaps = 1/235 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
V ++ EQL+Q + KA +K + E DL L L K E K+L+ Q+ E+
Sbjct: 1205 VEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQEL 1264
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
QSK + R +L+ KL E + L EAE + +L+K SL++QL+DT+ L
Sbjct: 1265 QSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELL 1324
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEG 559
EE R++ + K R LE + +++++Q++EE E K +L+R +S N QL SK + +
Sbjct: 1325 QEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLN--IQLSDSKKKLQD 1382
Query: 560 VARS-EELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
A + E LEE K++ Q + + E LEKTK RL E++DL +++D
Sbjct: 1383 FASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLD 1437
Score = 77.8 bits (183), Expect = 4e-14
Identities = 62/239 (25%), Positives = 114/239 (47%), Gaps = 5/239 (2%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDH----LSNEKAAQEKIVKQLQHQ 187
+ ++ +Q ++ K EK + + E++DL LD+ +SN + Q K + L +
Sbjct: 1401 IENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEE 1460
Query: 188 LNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDT 367
N ADE +R +A ++ + L R LEEA +L + L ++ED
Sbjct: 1461 KNISSKYADERDRA----EAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDL 1516
Query: 368 KRLADEEARERATLLGKFRNLEHDLDNIREQVEE-EAEGKADLQRQLSKANAEAQLWRSK 544
D+ + L R LE ++ ++ Q+EE E E +A +L + Q + +
Sbjct: 1517 VSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKL-RLEVNMQALKGQ 1575
Query: 545 YESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
+E + AR E+ EE +R+LQ +L E E +E ++ K++L +++DL+L+ D
Sbjct: 1576 FERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQAD 1634
Score = 71.3 bits (167), Expect = 4e-12
Identities = 58/232 (25%), Positives = 110/232 (47%), Gaps = 3/232 (1%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFS---EVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQS 205
E+ D+ +L+A+ +K Q ++ + A L EK E +K+L+ ++ +
Sbjct: 933 EEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVM-- 990
Query: 206 KADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADE 385
D+ N N L +K L SDL L E E + L+K+K + + + + +
Sbjct: 991 --DDQN---NKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKK 1045
Query: 386 EARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVA 565
E + R L R LE D + EQ+ + A+L+ QL+K E Q ++ + E
Sbjct: 1046 EEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQ 1105
Query: 566 RSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
++ L++ R+L+ +++ +E ++S EK K+ L E+E L+ E++
Sbjct: 1106 KNNALKKI-RELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELE 1156
Score = 68.5 bits (160), Expect = 3e-11
Identities = 53/208 (25%), Positives = 100/208 (48%), Gaps = 1/208 (0%)
Frame = +2
Query: 62 KAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDL 241
K + E AQ E+ + + ++ +S+ K +Q + NE+ ++ A +
Sbjct: 1731 KRRLEARIAQLEEELEEEQGNMEAMSDRV---RKATQQAEQLSNELATERSTAQKN---- 1783
Query: 242 DAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVS-LTTQLEDTKRLADEEARERATLLGK 418
++A+++L +N +L +L E E V K ++ L ++ + ++EARE+
Sbjct: 1784 ESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKS 1843
Query: 419 FRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRK 598
+ + L I QVE+E + + Q K NA + + + E E S+ + +RK
Sbjct: 1844 LKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLE-EAEEESQRINANRRK 1902
Query: 599 LQARLAEAEETIESLNQKVVALEKTKQR 682
LQ L EA E+ E++ ++V AL K+K R
Sbjct: 1903 LQRELDEATESNEAMGREVNAL-KSKLR 1929
Score = 63.7 bits (148), Expect = 7e-10
Identities = 59/241 (24%), Positives = 108/241 (44%), Gaps = 8/241 (3%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDH-LSNEKAAQEKIVKQLQHQLNE 196
+ +M QL++L E + + + L+ + L E+ +QLQ QL+E
Sbjct: 1541 MEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHE 1600
Query: 197 VQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEA----ESQVSQLSKIKVSL---TTQ 355
+++ ++ + AAKKKL + DL Q + A E + QL K++ + +
Sbjct: 1601 YETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRE 1660
Query: 356 LEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLW 535
LED + DE K ++LE DL ++E + A +A Q L K +L
Sbjct: 1661 LEDARASRDEIFATAKENEKKAKSLEADLMQLQEDL--AAAERARKQADLEKEELAEEL- 1717
Query: 536 RSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLE 715
+ ++ L++ KR+L+AR+A+ EE +E + A+ ++ + E L E
Sbjct: 1718 -----ASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNE 1772
Query: 716 V 718
+
Sbjct: 1773 L 1773
Score = 62.9 bits (146), Expect = 1e-09
Identities = 58/233 (24%), Positives = 113/233 (48%), Gaps = 3/233 (1%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD 214
++L+Q + + + + +L A + + AA+++ +L+ L+E++++ +
Sbjct: 876 KELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQ---ELEEILHEMEARLE 932
Query: 215 EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADE--E 388
E L A +KK++ + DL QLEE E+ +L KV+ ++ K+L DE
Sbjct: 933 EEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKI---KKLEDEILV 989
Query: 389 ARERATLLGKFRN-LEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVA 565
++ L K R LE + ++ + EE E +L + +K + + + E +
Sbjct: 990 MDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKS 1049
Query: 566 RSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
R +ELE+ KRKL+ ++ E I L ++ L K +LA + E+LQ + R
Sbjct: 1050 R-QELEKLKRKLEGDASDFHEQIADLQAQIAEL---KMQLAKKEEELQAALAR 1098
Score = 56.0 bits (129), Expect = 1e-07
Identities = 53/245 (21%), Positives = 105/245 (42%), Gaps = 21/245 (8%)
Frame = +2
Query: 44 DQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEAN 223
DQ NKL K R ++DL L + K+ + + ++E++ + +
Sbjct: 992 DQNNKLS----KERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEE 1047
Query: 224 RTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERA 403
++ +L+ K+KL + SD Q+ + ++Q+++L +L+ D+E ++
Sbjct: 1048 KSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKN 1107
Query: 404 TLLGKFR-------NLEHDLDNIREQVEEEAEGKADLQRQLS----------KANAEAQL 532
L K R +L+ DLD+ R + + K DL +L + A Q
Sbjct: 1108 NALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQE 1167
Query: 533 WRSKYESEGVARSEELEEAKRKLQARLAEAE----ETIESLNQKVVALEKTKQRLATEVE 700
R+K E E + L+E R +A++ E + +E L +++ ++ K L +
Sbjct: 1168 LRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQ 1227
Query: 701 DLQLE 715
L+ E
Sbjct: 1228 TLEKE 1232
Score = 56.0 bits (129), Expect = 1e-07
Identities = 50/235 (21%), Positives = 106/235 (45%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+SD+ E LD + KAEK + E+ L+ L+ + A Q+++ + + ++ +
Sbjct: 1120 ISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVL 1179
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
+ DE R+ +A +++ +++ + +L E Q+ Q + K +L + ++
Sbjct: 1180 KKALDEETRS---HEAQVQEMRQKHAQAVEELTE---QLEQFKRAKANLDKNKQTLEKEN 1233
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEG 559
+ A E L + +EH + QV+E +D +R ++ N + +++ ES
Sbjct: 1234 ADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESV- 1292
Query: 560 VARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
E E KL +A ++ + + E+T+Q+L + QLE +R
Sbjct: 1293 TGMLNEAEGKAIKLAKDVASLSSQLQDTQE--LLQEETRQKLNVSTKLRQLEEER 1345
Score = 53.2 bits (122), Expect = 1e-06
Identities = 44/200 (22%), Positives = 95/200 (47%), Gaps = 10/200 (5%)
Frame = +2
Query: 155 QEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLE-------EAESQ 313
QE+ ++ + +L + + + +A L +L+ +L+ E + L QL+ EAE
Sbjct: 850 QEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEM 909
Query: 314 VSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADL 493
+L+ K L L + + +EE L + + + + ++ EQ+EEE + L
Sbjct: 910 RVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKL 969
Query: 494 QRQLSKANAEAQLWRSKYESEGVA---RSEELEEAKRKLQARLAEAEETIESLNQKVVAL 664
QL K AEA++ K E E + ++ +L + ++ L+ R+++ + +K L
Sbjct: 970 --QLEKVTAEAKI--KKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNL 1025
Query: 665 EKTKQRLATEVEDLQLEVDR 724
K K + + + +L++ + +
Sbjct: 1026 TKLKNKHESMISELEVRLKK 1045
Score = 48.4 bits (110), Expect = 3e-05
Identities = 49/229 (21%), Positives = 100/229 (43%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD 214
E L + + +A+ + + E+ +G + L +EK E + QL+ +L E Q +
Sbjct: 1694 EDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNME 1753
Query: 215 EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEAR 394
+ + ++LS E + ++ ES QL + L ++L + + +++
Sbjct: 1754 AMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAV--KSK 1811
Query: 395 ERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSE 574
++T+ LE + + EQVE+EA K + L + + + + + E E +E
Sbjct: 1812 FKSTIAA----LEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDER-KMAE 1866
Query: 575 ELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
+ +E K AR+ + + +E E+ QR+ LQ E+D
Sbjct: 1867 QYKEQAEKGNARVKQLKRQLEEA-------EEESQRINANRRKLQRELD 1908
Score = 43.6 bits (98), Expect = 8e-04
Identities = 28/122 (22%), Positives = 55/122 (45%)
Frame = +2
Query: 59 LKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLND 238
+K+K + A +++ L ++ + EK A K +KQ +L E+ + ++ +
Sbjct: 1808 VKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQ 1867
Query: 239 LDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGK 418
+K + L RQLEEAE + +++ + L +L++ + RE L K
Sbjct: 1868 YKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSK 1927
Query: 419 FR 424
R
Sbjct: 1928 LR 1929
>AY520817-1|AAS98911.1| 1945|Homo sapiens smooth muscle myosin heavy
chain isoform SM2 protein.
Length = 1945
Score = 129 bits (311), Expect = 1e-29
Identities = 79/235 (33%), Positives = 126/235 (53%), Gaps = 1/235 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
V ++ EQL+Q + KA +K + E DL L L K E K+L+ Q+ E+
Sbjct: 1212 VEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQEL 1271
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
QSK + R +L+ KL E + L EAE + +L+K SL++QL+DT+ L
Sbjct: 1272 QSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELL 1331
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEG 559
EE R++ + K R LE + +++++Q++EE E K +L+R +S N QL SK + +
Sbjct: 1332 QEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLN--IQLSDSKKKLQD 1389
Query: 560 VARS-EELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
A + E LEE K++ Q + + E LEKTK RL E++DL +++D
Sbjct: 1390 FASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLD 1444
Score = 77.8 bits (183), Expect = 4e-14
Identities = 62/239 (25%), Positives = 114/239 (47%), Gaps = 5/239 (2%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDH----LSNEKAAQEKIVKQLQHQ 187
+ ++ +Q ++ K EK + + E++DL LD+ +SN + Q K + L +
Sbjct: 1408 IENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEE 1467
Query: 188 LNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDT 367
N ADE +R +A ++ + L R LEEA +L + L ++ED
Sbjct: 1468 KNISSKYADERDRA----EAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDL 1523
Query: 368 KRLADEEARERATLLGKFRNLEHDLDNIREQVEE-EAEGKADLQRQLSKANAEAQLWRSK 544
D+ + L R LE ++ ++ Q+EE E E +A +L + Q + +
Sbjct: 1524 VSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKL-RLEVNMQALKGQ 1582
Query: 545 YESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
+E + AR E+ EE +R+LQ +L E E +E ++ K++L +++DL+L+ D
Sbjct: 1583 FERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQAD 1641
Score = 71.3 bits (167), Expect = 4e-12
Identities = 58/232 (25%), Positives = 110/232 (47%), Gaps = 3/232 (1%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFS---EVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQS 205
E+ D+ +L+A+ +K Q ++ + A L EK E +K+L+ ++ +
Sbjct: 940 EEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVM-- 997
Query: 206 KADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADE 385
D+ N N L +K L SDL L E E + L+K+K + + + + +
Sbjct: 998 --DDQN---NKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKK 1052
Query: 386 EARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVA 565
E + R L R LE D + EQ+ + A+L+ QL+K E Q ++ + E
Sbjct: 1053 EEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQ 1112
Query: 566 RSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
++ L++ R+L+ +++ +E ++S EK K+ L E+E L+ E++
Sbjct: 1113 KNNALKKI-RELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELE 1163
Score = 68.5 bits (160), Expect = 3e-11
Identities = 53/208 (25%), Positives = 100/208 (48%), Gaps = 1/208 (0%)
Frame = +2
Query: 62 KAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDL 241
K + E AQ E+ + + ++ +S+ K +Q + NE+ ++ A +
Sbjct: 1738 KRRLEARIAQLEEELEEEQGNMEAMSDRV---RKATQQAEQLSNELATERSTAQKN---- 1790
Query: 242 DAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVS-LTTQLEDTKRLADEEARERATLLGK 418
++A+++L +N +L +L E E V K ++ L ++ + ++EARE+
Sbjct: 1791 ESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKS 1850
Query: 419 FRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRK 598
+ + L I QVE+E + + Q K NA + + + E E S+ + +RK
Sbjct: 1851 LKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLE-EAEEESQRINANRRK 1909
Query: 599 LQARLAEAEETIESLNQKVVALEKTKQR 682
LQ L EA E+ E++ ++V AL K+K R
Sbjct: 1910 LQRELDEATESNEAMGREVNAL-KSKLR 1936
Score = 63.7 bits (148), Expect = 7e-10
Identities = 59/241 (24%), Positives = 108/241 (44%), Gaps = 8/241 (3%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDH-LSNEKAAQEKIVKQLQHQLNE 196
+ +M QL++L E + + + L+ + L E+ +QLQ QL+E
Sbjct: 1548 MEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHE 1607
Query: 197 VQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEA----ESQVSQLSKIKVSL---TTQ 355
+++ ++ + AAKKKL + DL Q + A E + QL K++ + +
Sbjct: 1608 YETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRE 1667
Query: 356 LEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLW 535
LED + DE K ++LE DL ++E + A +A Q L K +L
Sbjct: 1668 LEDARASRDEIFATAKENEKKAKSLEADLMQLQEDL--AAAERARKQADLEKEELAEEL- 1724
Query: 536 RSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLE 715
+ ++ L++ KR+L+AR+A+ EE +E + A+ ++ + E L E
Sbjct: 1725 -----ASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNE 1779
Query: 716 V 718
+
Sbjct: 1780 L 1780
Score = 62.9 bits (146), Expect = 1e-09
Identities = 58/233 (24%), Positives = 113/233 (48%), Gaps = 3/233 (1%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD 214
++L+Q + + + + +L A + + AA+++ +L+ L+E++++ +
Sbjct: 883 KELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQ---ELEEILHEMEARLE 939
Query: 215 EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADE--E 388
E L A +KK++ + DL QLEE E+ +L KV+ ++ K+L DE
Sbjct: 940 EEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKI---KKLEDEILV 996
Query: 389 ARERATLLGKFRN-LEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVA 565
++ L K R LE + ++ + EE E +L + +K + + + E +
Sbjct: 997 MDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKS 1056
Query: 566 RSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
R +ELE+ KRKL+ ++ E I L ++ L K +LA + E+LQ + R
Sbjct: 1057 R-QELEKLKRKLEGDASDFHEQIADLQAQIAEL---KMQLAKKEEELQAALAR 1105
Score = 56.0 bits (129), Expect = 1e-07
Identities = 53/245 (21%), Positives = 105/245 (42%), Gaps = 21/245 (8%)
Frame = +2
Query: 44 DQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEAN 223
DQ NKL K R ++DL L + K+ + + ++E++ + +
Sbjct: 999 DQNNKLS----KERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEE 1054
Query: 224 RTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERA 403
++ +L+ K+KL + SD Q+ + ++Q+++L +L+ D+E ++
Sbjct: 1055 KSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKN 1114
Query: 404 TLLGKFR-------NLEHDLDNIREQVEEEAEGKADLQRQLS----------KANAEAQL 532
L K R +L+ DLD+ R + + K DL +L + A Q
Sbjct: 1115 NALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQE 1174
Query: 533 WRSKYESEGVARSEELEEAKRKLQARLAEAE----ETIESLNQKVVALEKTKQRLATEVE 700
R+K E E + L+E R +A++ E + +E L +++ ++ K L +
Sbjct: 1175 LRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQ 1234
Query: 701 DLQLE 715
L+ E
Sbjct: 1235 TLEKE 1239
Score = 56.0 bits (129), Expect = 1e-07
Identities = 50/235 (21%), Positives = 106/235 (45%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+SD+ E LD + KAEK + E+ L+ L+ + A Q+++ + + ++ +
Sbjct: 1127 ISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVL 1186
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
+ DE R+ +A +++ +++ + +L E Q+ Q + K +L + ++
Sbjct: 1187 KKALDEETRS---HEAQVQEMRQKHAQAVEELTE---QLEQFKRAKANLDKNKQTLEKEN 1240
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEG 559
+ A E L + +EH + QV+E +D +R ++ N + +++ ES
Sbjct: 1241 ADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESV- 1299
Query: 560 VARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
E E KL +A ++ + + E+T+Q+L + QLE +R
Sbjct: 1300 TGMLNEAEGKAIKLAKDVASLSSQLQDTQE--LLQEETRQKLNVSTKLRQLEEER 1352
Score = 53.2 bits (122), Expect = 1e-06
Identities = 44/200 (22%), Positives = 95/200 (47%), Gaps = 10/200 (5%)
Frame = +2
Query: 155 QEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLE-------EAESQ 313
QE+ ++ + +L + + + +A L +L+ +L+ E + L QL+ EAE
Sbjct: 857 QEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEM 916
Query: 314 VSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADL 493
+L+ K L L + + +EE L + + + + ++ EQ+EEE + L
Sbjct: 917 RVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKL 976
Query: 494 QRQLSKANAEAQLWRSKYESEGVA---RSEELEEAKRKLQARLAEAEETIESLNQKVVAL 664
QL K AEA++ K E E + ++ +L + ++ L+ R+++ + +K L
Sbjct: 977 --QLEKVTAEAKI--KKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNL 1032
Query: 665 EKTKQRLATEVEDLQLEVDR 724
K K + + + +L++ + +
Sbjct: 1033 TKLKNKHESMISELEVRLKK 1052
Score = 48.4 bits (110), Expect = 3e-05
Identities = 49/229 (21%), Positives = 100/229 (43%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD 214
E L + + +A+ + + E+ +G + L +EK E + QL+ +L E Q +
Sbjct: 1701 EDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNME 1760
Query: 215 EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEAR 394
+ + ++LS E + ++ ES QL + L ++L + + +++
Sbjct: 1761 AMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAV--KSK 1818
Query: 395 ERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSE 574
++T+ LE + + EQVE+EA K + L + + + + + E E +E
Sbjct: 1819 FKSTIAA----LEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDER-KMAE 1873
Query: 575 ELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
+ +E K AR+ + + +E E+ QR+ LQ E+D
Sbjct: 1874 QYKEQAEKGNARVKQLKRQLEEA-------EEESQRINANRRKLQRELD 1915
Score = 43.6 bits (98), Expect = 8e-04
Identities = 28/122 (22%), Positives = 55/122 (45%)
Frame = +2
Query: 59 LKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLND 238
+K+K + A +++ L ++ + EK A K +KQ +L E+ + ++ +
Sbjct: 1815 VKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQ 1874
Query: 239 LDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGK 418
+K + L RQLEEAE + +++ + L +L++ + RE L K
Sbjct: 1875 YKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSK 1934
Query: 419 FR 424
R
Sbjct: 1935 LR 1936
>AY520816-1|AAS98910.1| 1979|Homo sapiens smooth muscle myosin heavy
chain isoform SM1 protein.
Length = 1979
Score = 129 bits (311), Expect = 1e-29
Identities = 79/235 (33%), Positives = 126/235 (53%), Gaps = 1/235 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
V ++ EQL+Q + KA +K + E DL L L K E K+L+ Q+ E+
Sbjct: 1212 VEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQEL 1271
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
QSK + R +L+ KL E + L EAE + +L+K SL++QL+DT+ L
Sbjct: 1272 QSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELL 1331
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEG 559
EE R++ + K R LE + +++++Q++EE E K +L+R +S N QL SK + +
Sbjct: 1332 QEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLN--IQLSDSKKKLQD 1389
Query: 560 VARS-EELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
A + E LEE K++ Q + + E LEKTK RL E++DL +++D
Sbjct: 1390 FASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLD 1444
Score = 77.8 bits (183), Expect = 4e-14
Identities = 62/239 (25%), Positives = 114/239 (47%), Gaps = 5/239 (2%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDH----LSNEKAAQEKIVKQLQHQ 187
+ ++ +Q ++ K EK + + E++DL LD+ +SN + Q K + L +
Sbjct: 1408 IENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEE 1467
Query: 188 LNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDT 367
N ADE +R +A ++ + L R LEEA +L + L ++ED
Sbjct: 1468 KNISSKYADERDRA----EAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDL 1523
Query: 368 KRLADEEARERATLLGKFRNLEHDLDNIREQVEE-EAEGKADLQRQLSKANAEAQLWRSK 544
D+ + L R LE ++ ++ Q+EE E E +A +L + Q + +
Sbjct: 1524 VSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKL-RLEVNMQALKGQ 1582
Query: 545 YESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
+E + AR E+ EE +R+LQ +L E E +E ++ K++L +++DL+L+ D
Sbjct: 1583 FERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQAD 1641
Score = 71.3 bits (167), Expect = 4e-12
Identities = 58/232 (25%), Positives = 110/232 (47%), Gaps = 3/232 (1%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFS---EVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQS 205
E+ D+ +L+A+ +K Q ++ + A L EK E +K+L+ ++ +
Sbjct: 940 EEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVM-- 997
Query: 206 KADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADE 385
D+ N N L +K L SDL L E E + L+K+K + + + + +
Sbjct: 998 --DDQN---NKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKK 1052
Query: 386 EARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVA 565
E + R L R LE D + EQ+ + A+L+ QL+K E Q ++ + E
Sbjct: 1053 EEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQ 1112
Query: 566 RSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
++ L++ R+L+ +++ +E ++S EK K+ L E+E L+ E++
Sbjct: 1113 KNNALKKI-RELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELE 1163
Score = 69.7 bits (163), Expect = 1e-11
Identities = 54/212 (25%), Positives = 101/212 (47%), Gaps = 1/212 (0%)
Frame = +2
Query: 62 KAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDL 241
K + E AQ E+ + + ++ +S+ K +Q + NE+ ++ A +
Sbjct: 1738 KRRLEARIAQLEEELEEEQGNMEAMSDRV---RKATQQAEQLSNELATERSTAQKN---- 1790
Query: 242 DAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVS-LTTQLEDTKRLADEEARERATLLGK 418
++A+++L +N +L +L E E V K ++ L ++ + ++EARE+
Sbjct: 1791 ESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKS 1850
Query: 419 FRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRK 598
+ + L I QVE+E + + Q K NA + + + E E S+ + +RK
Sbjct: 1851 LKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLE-EAEEESQRINANRRK 1909
Query: 599 LQARLAEAEETIESLNQKVVALEKTKQRLATE 694
LQ L EA E+ E++ ++V AL K+K R E
Sbjct: 1910 LQRELDEATESNEAMGREVNAL-KSKLRRGNE 1940
Score = 63.7 bits (148), Expect = 7e-10
Identities = 59/241 (24%), Positives = 108/241 (44%), Gaps = 8/241 (3%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDH-LSNEKAAQEKIVKQLQHQLNE 196
+ +M QL++L E + + + L+ + L E+ +QLQ QL+E
Sbjct: 1548 MEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHE 1607
Query: 197 VQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEA----ESQVSQLSKIKVSL---TTQ 355
+++ ++ + AAKKKL + DL Q + A E + QL K++ + +
Sbjct: 1608 YETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRE 1667
Query: 356 LEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLW 535
LED + DE K ++LE DL ++E + A +A Q L K +L
Sbjct: 1668 LEDARASRDEIFATAKENEKKAKSLEADLMQLQEDL--AAAERARKQADLEKEELAEEL- 1724
Query: 536 RSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLE 715
+ ++ L++ KR+L+AR+A+ EE +E + A+ ++ + E L E
Sbjct: 1725 -----ASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNE 1779
Query: 716 V 718
+
Sbjct: 1780 L 1780
Score = 62.9 bits (146), Expect = 1e-09
Identities = 58/233 (24%), Positives = 113/233 (48%), Gaps = 3/233 (1%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD 214
++L+Q + + + + +L A + + AA+++ +L+ L+E++++ +
Sbjct: 883 KELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQ---ELEEILHEMEARLE 939
Query: 215 EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADE--E 388
E L A +KK++ + DL QLEE E+ +L KV+ ++ K+L DE
Sbjct: 940 EEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKI---KKLEDEILV 996
Query: 389 ARERATLLGKFRN-LEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVA 565
++ L K R LE + ++ + EE E +L + +K + + + E +
Sbjct: 997 MDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKS 1056
Query: 566 RSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
R +ELE+ KRKL+ ++ E I L ++ L K +LA + E+LQ + R
Sbjct: 1057 R-QELEKLKRKLEGDASDFHEQIADLQAQIAEL---KMQLAKKEEELQAALAR 1105
Score = 56.0 bits (129), Expect = 1e-07
Identities = 53/245 (21%), Positives = 105/245 (42%), Gaps = 21/245 (8%)
Frame = +2
Query: 44 DQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEAN 223
DQ NKL K R ++DL L + K+ + + ++E++ + +
Sbjct: 999 DQNNKLS----KERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEE 1054
Query: 224 RTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERA 403
++ +L+ K+KL + SD Q+ + ++Q+++L +L+ D+E ++
Sbjct: 1055 KSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKN 1114
Query: 404 TLLGKFR-------NLEHDLDNIREQVEEEAEGKADLQRQLS----------KANAEAQL 532
L K R +L+ DLD+ R + + K DL +L + A Q
Sbjct: 1115 NALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQE 1174
Query: 533 WRSKYESEGVARSEELEEAKRKLQARLAEAE----ETIESLNQKVVALEKTKQRLATEVE 700
R+K E E + L+E R +A++ E + +E L +++ ++ K L +
Sbjct: 1175 LRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQ 1234
Query: 701 DLQLE 715
L+ E
Sbjct: 1235 TLEKE 1239
Score = 56.0 bits (129), Expect = 1e-07
Identities = 50/235 (21%), Positives = 106/235 (45%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+SD+ E LD + KAEK + E+ L+ L+ + A Q+++ + + ++ +
Sbjct: 1127 ISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVL 1186
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
+ DE R+ +A +++ +++ + +L E Q+ Q + K +L + ++
Sbjct: 1187 KKALDEETRS---HEAQVQEMRQKHAQAVEELTE---QLEQFKRAKANLDKNKQTLEKEN 1240
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEG 559
+ A E L + +EH + QV+E +D +R ++ N + +++ ES
Sbjct: 1241 ADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESV- 1299
Query: 560 VARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
E E KL +A ++ + + E+T+Q+L + QLE +R
Sbjct: 1300 TGMLNEAEGKAIKLAKDVASLSSQLQDTQE--LLQEETRQKLNVSTKLRQLEEER 1352
Score = 53.2 bits (122), Expect = 1e-06
Identities = 44/200 (22%), Positives = 95/200 (47%), Gaps = 10/200 (5%)
Frame = +2
Query: 155 QEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLE-------EAESQ 313
QE+ ++ + +L + + + +A L +L+ +L+ E + L QL+ EAE
Sbjct: 857 QEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEM 916
Query: 314 VSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADL 493
+L+ K L L + + +EE L + + + + ++ EQ+EEE + L
Sbjct: 917 RVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKL 976
Query: 494 QRQLSKANAEAQLWRSKYESEGVA---RSEELEEAKRKLQARLAEAEETIESLNQKVVAL 664
QL K AEA++ K E E + ++ +L + ++ L+ R+++ + +K L
Sbjct: 977 --QLEKVTAEAKI--KKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNL 1032
Query: 665 EKTKQRLATEVEDLQLEVDR 724
K K + + + +L++ + +
Sbjct: 1033 TKLKNKHESMISELEVRLKK 1052
Score = 48.4 bits (110), Expect = 3e-05
Identities = 49/229 (21%), Positives = 100/229 (43%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD 214
E L + + +A+ + + E+ +G + L +EK E + QL+ +L E Q +
Sbjct: 1701 EDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNME 1760
Query: 215 EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEAR 394
+ + ++LS E + ++ ES QL + L ++L + + +++
Sbjct: 1761 AMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAV--KSK 1818
Query: 395 ERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSE 574
++T+ LE + + EQVE+EA K + L + + + + + E E +E
Sbjct: 1819 FKSTIAA----LEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDER-KMAE 1873
Query: 575 ELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
+ +E K AR+ + + +E E+ QR+ LQ E+D
Sbjct: 1874 QYKEQAEKGNARVKQLKRQLEEA-------EEESQRINANRRKLQRELD 1915
Score = 43.6 bits (98), Expect = 8e-04
Identities = 28/122 (22%), Positives = 55/122 (45%)
Frame = +2
Query: 59 LKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLND 238
+K+K + A +++ L ++ + EK A K +KQ +L E+ + ++ +
Sbjct: 1815 VKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQ 1874
Query: 239 LDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGK 418
+K + L RQLEEAE + +++ + L +L++ + RE L K
Sbjct: 1875 YKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSK 1934
Query: 419 FR 424
R
Sbjct: 1935 LR 1936
>AF001548-1|AAC31665.1| 1857|Homo sapiens Myosin heavy chain (MHY11)
(5'partial) protein.
Length = 1857
Score = 129 bits (311), Expect = 1e-29
Identities = 79/235 (33%), Positives = 126/235 (53%), Gaps = 1/235 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
V ++ EQL+Q + KA +K + E DL L L K E K+L+ Q+ E+
Sbjct: 1090 VEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQEL 1149
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
QSK + R +L+ KL E + L EAE + +L+K SL++QL+DT+ L
Sbjct: 1150 QSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELL 1209
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEG 559
EE R++ + K R LE + +++++Q++EE E K +L+R +S N QL SK + +
Sbjct: 1210 QEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLN--IQLSDSKKKLQD 1267
Query: 560 VARS-EELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
A + E LEE K++ Q + + E LEKTK RL E++DL +++D
Sbjct: 1268 FASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLD 1322
Score = 77.8 bits (183), Expect = 4e-14
Identities = 62/239 (25%), Positives = 114/239 (47%), Gaps = 5/239 (2%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDH----LSNEKAAQEKIVKQLQHQ 187
+ ++ +Q ++ K EK + + E++DL LD+ +SN + Q K + L +
Sbjct: 1286 IENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEE 1345
Query: 188 LNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDT 367
N ADE +R +A ++ + L R LEEA +L + L ++ED
Sbjct: 1346 KNISSKYADERDRA----EAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDL 1401
Query: 368 KRLADEEARERATLLGKFRNLEHDLDNIREQVEE-EAEGKADLQRQLSKANAEAQLWRSK 544
D+ + L R LE ++ ++ Q+EE E E +A +L + Q + +
Sbjct: 1402 VSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKL-RLEVNMQALKGQ 1460
Query: 545 YESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
+E + AR E+ EE +R+LQ +L E E +E ++ K++L +++DL+L+ D
Sbjct: 1461 FERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQAD 1519
Score = 71.3 bits (167), Expect = 4e-12
Identities = 58/232 (25%), Positives = 110/232 (47%), Gaps = 3/232 (1%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFS---EVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQS 205
E+ D+ +L+A+ +K Q ++ + A L EK E +K+L+ ++ +
Sbjct: 818 EEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVM-- 875
Query: 206 KADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADE 385
D+ N N L +K L SDL L E E + L+K+K + + + + +
Sbjct: 876 --DDQN---NKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKK 930
Query: 386 EARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVA 565
E + R L R LE D + EQ+ + A+L+ QL+K E Q ++ + E
Sbjct: 931 EEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQ 990
Query: 566 RSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
++ L++ R+L+ +++ +E ++S EK K+ L E+E L+ E++
Sbjct: 991 KNNALKKI-RELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELE 1041
Score = 69.7 bits (163), Expect = 1e-11
Identities = 54/212 (25%), Positives = 101/212 (47%), Gaps = 1/212 (0%)
Frame = +2
Query: 62 KAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDL 241
K + E AQ E+ + + ++ +S+ K +Q + NE+ ++ A +
Sbjct: 1616 KRRLEARIAQLEEELEEEQGNMEAMSDRV---RKATQQAEQLSNELATERSTAQKN---- 1668
Query: 242 DAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVS-LTTQLEDTKRLADEEARERATLLGK 418
++A+++L +N +L +L E E V K ++ L ++ + ++EARE+
Sbjct: 1669 ESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKS 1728
Query: 419 FRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRK 598
+ + L I QVE+E + + Q K NA + + + E E S+ + +RK
Sbjct: 1729 LKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLE-EAEEESQRINANRRK 1787
Query: 599 LQARLAEAEETIESLNQKVVALEKTKQRLATE 694
LQ L EA E+ E++ ++V AL K+K R E
Sbjct: 1788 LQRELDEATESNEAMGREVNAL-KSKLRRGNE 1818
Score = 63.7 bits (148), Expect = 7e-10
Identities = 59/241 (24%), Positives = 108/241 (44%), Gaps = 8/241 (3%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDH-LSNEKAAQEKIVKQLQHQLNE 196
+ +M QL++L E + + + L+ + L E+ +QLQ QL+E
Sbjct: 1426 MEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHE 1485
Query: 197 VQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEA----ESQVSQLSKIKVSL---TTQ 355
+++ ++ + AAKKKL + DL Q + A E + QL K++ + +
Sbjct: 1486 YETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRE 1545
Query: 356 LEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLW 535
LED + DE K ++LE DL ++E + A +A Q L K +L
Sbjct: 1546 LEDARASRDEIFATAKENEKKAKSLEADLMQLQEDL--AAAERARKQADLEKEELAEEL- 1602
Query: 536 RSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLE 715
+ ++ L++ KR+L+AR+A+ EE +E + A+ ++ + E L E
Sbjct: 1603 -----ASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNE 1657
Query: 716 V 718
+
Sbjct: 1658 L 1658
Score = 62.9 bits (146), Expect = 1e-09
Identities = 58/233 (24%), Positives = 113/233 (48%), Gaps = 3/233 (1%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD 214
++L+Q + + + + +L A + + AA+++ +L+ L+E++++ +
Sbjct: 761 KELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQ---ELEEILHEMEARLE 817
Query: 215 EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADE--E 388
E L A +KK++ + DL QLEE E+ +L KV+ ++ K+L DE
Sbjct: 818 EEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKI---KKLEDEILV 874
Query: 389 ARERATLLGKFRN-LEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVA 565
++ L K R LE + ++ + EE E +L + +K + + + E +
Sbjct: 875 MDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKS 934
Query: 566 RSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
R +ELE+ KRKL+ ++ E I L ++ L K +LA + E+LQ + R
Sbjct: 935 R-QELEKLKRKLEGDASDFHEQIADLQAQIAEL---KMQLAKKEEELQAALAR 983
Score = 56.0 bits (129), Expect = 1e-07
Identities = 53/245 (21%), Positives = 105/245 (42%), Gaps = 21/245 (8%)
Frame = +2
Query: 44 DQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEAN 223
DQ NKL K R ++DL L + K+ + + ++E++ + +
Sbjct: 877 DQNNKLS----KERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEE 932
Query: 224 RTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERA 403
++ +L+ K+KL + SD Q+ + ++Q+++L +L+ D+E ++
Sbjct: 933 KSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKN 992
Query: 404 TLLGKFR-------NLEHDLDNIREQVEEEAEGKADLQRQLS----------KANAEAQL 532
L K R +L+ DLD+ R + + K DL +L + A Q
Sbjct: 993 NALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQE 1052
Query: 533 WRSKYESEGVARSEELEEAKRKLQARLAEAE----ETIESLNQKVVALEKTKQRLATEVE 700
R+K E E + L+E R +A++ E + +E L +++ ++ K L +
Sbjct: 1053 LRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQ 1112
Query: 701 DLQLE 715
L+ E
Sbjct: 1113 TLEKE 1117
Score = 56.0 bits (129), Expect = 1e-07
Identities = 50/235 (21%), Positives = 106/235 (45%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+SD+ E LD + KAEK + E+ L+ L+ + A Q+++ + + ++ +
Sbjct: 1005 ISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVL 1064
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
+ DE R+ +A +++ +++ + +L E Q+ Q + K +L + ++
Sbjct: 1065 KKALDEETRS---HEAQVQEMRQKHAQAVEELTE---QLEQFKRAKANLDKNKQTLEKEN 1118
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEG 559
+ A E L + +EH + QV+E +D +R ++ N + +++ ES
Sbjct: 1119 ADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESV- 1177
Query: 560 VARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
E E KL +A ++ + + E+T+Q+L + QLE +R
Sbjct: 1178 TGMLNEAEGKAIKLAKDVASLSSQLQDTQE--LLQEETRQKLNVSTKLRQLEEER 1230
Score = 53.2 bits (122), Expect = 1e-06
Identities = 44/200 (22%), Positives = 95/200 (47%), Gaps = 10/200 (5%)
Frame = +2
Query: 155 QEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLE-------EAESQ 313
QE+ ++ + +L + + + +A L +L+ +L+ E + L QL+ EAE
Sbjct: 735 QEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEM 794
Query: 314 VSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADL 493
+L+ K L L + + +EE L + + + + ++ EQ+EEE + L
Sbjct: 795 RVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKL 854
Query: 494 QRQLSKANAEAQLWRSKYESEGVA---RSEELEEAKRKLQARLAEAEETIESLNQKVVAL 664
QL K AEA++ K E E + ++ +L + ++ L+ R+++ + +K L
Sbjct: 855 --QLEKVTAEAKI--KKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNL 910
Query: 665 EKTKQRLATEVEDLQLEVDR 724
K K + + + +L++ + +
Sbjct: 911 TKLKNKHESMISELEVRLKK 930
Score = 48.4 bits (110), Expect = 3e-05
Identities = 49/229 (21%), Positives = 100/229 (43%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD 214
E L + + +A+ + + E+ +G + L +EK E + QL+ +L E Q +
Sbjct: 1579 EDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNME 1638
Query: 215 EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEAR 394
+ + ++LS E + ++ ES QL + L ++L + + +++
Sbjct: 1639 AMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAV--KSK 1696
Query: 395 ERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSE 574
++T+ LE + + EQVE+EA K + L + + + + + E E +E
Sbjct: 1697 FKSTIAA----LEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDER-KMAE 1751
Query: 575 ELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
+ +E K AR+ + + +E E+ QR+ LQ E+D
Sbjct: 1752 QYKEQAEKGNARVKQLKRQLEEA-------EEESQRINANRRKLQRELD 1793
Score = 43.6 bits (98), Expect = 8e-04
Identities = 28/122 (22%), Positives = 55/122 (45%)
Frame = +2
Query: 59 LKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLND 238
+K+K + A +++ L ++ + EK A K +KQ +L E+ + ++ +
Sbjct: 1693 VKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQ 1752
Query: 239 LDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGK 418
+K + L RQLEEAE + +++ + L +L++ + RE L K
Sbjct: 1753 YKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSK 1812
Query: 419 FR 424
R
Sbjct: 1813 LR 1814
>AB020673-1|BAA74889.2| 1984|Homo sapiens KIAA0866 protein protein.
Length = 1984
Score = 129 bits (311), Expect = 1e-29
Identities = 79/235 (33%), Positives = 126/235 (53%), Gaps = 1/235 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
V ++ EQL+Q + KA +K + E DL L L K E K+L+ Q+ E+
Sbjct: 1217 VEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQEL 1276
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
QSK + R +L+ KL E + L EAE + +L+K SL++QL+DT+ L
Sbjct: 1277 QSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELL 1336
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEG 559
EE R++ + K R LE + +++++Q++EE E K +L+R +S N QL SK + +
Sbjct: 1337 QEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLN--IQLSDSKKKLQD 1394
Query: 560 VARS-EELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
A + E LEE K++ Q + + E LEKTK RL E++DL +++D
Sbjct: 1395 FASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLD 1449
Score = 77.8 bits (183), Expect = 4e-14
Identities = 62/239 (25%), Positives = 114/239 (47%), Gaps = 5/239 (2%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDH----LSNEKAAQEKIVKQLQHQ 187
+ ++ +Q ++ K EK + + E++DL LD+ +SN + Q K + L +
Sbjct: 1413 IENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEE 1472
Query: 188 LNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDT 367
N ADE +R +A ++ + L R LEEA +L + L ++ED
Sbjct: 1473 KNISSKYADERDRA----EAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDL 1528
Query: 368 KRLADEEARERATLLGKFRNLEHDLDNIREQVEE-EAEGKADLQRQLSKANAEAQLWRSK 544
D+ + L R LE ++ ++ Q+EE E E +A +L + Q + +
Sbjct: 1529 VSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKL-RLEVNMQALKGQ 1587
Query: 545 YESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
+E + AR E+ EE +R+LQ +L E E +E ++ K++L +++DL+L+ D
Sbjct: 1588 FERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQAD 1646
Score = 71.3 bits (167), Expect = 4e-12
Identities = 58/232 (25%), Positives = 110/232 (47%), Gaps = 3/232 (1%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFS---EVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQS 205
E+ D+ +L+A+ +K Q ++ + A L EK E +K+L+ ++ +
Sbjct: 945 EEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVM-- 1002
Query: 206 KADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADE 385
D+ N N L +K L SDL L E E + L+K+K + + + + +
Sbjct: 1003 --DDQN---NKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKK 1057
Query: 386 EARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVA 565
E + R L R LE D + EQ+ + A+L+ QL+K E Q ++ + E
Sbjct: 1058 EEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQ 1117
Query: 566 RSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
++ L++ R+L+ +++ +E ++S EK K+ L E+E L+ E++
Sbjct: 1118 KNNALKKI-RELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELE 1168
Score = 69.7 bits (163), Expect = 1e-11
Identities = 54/212 (25%), Positives = 101/212 (47%), Gaps = 1/212 (0%)
Frame = +2
Query: 62 KAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDL 241
K + E AQ E+ + + ++ +S+ K +Q + NE+ ++ A +
Sbjct: 1743 KRRLEARIAQLEEELEEEQGNMEAMSDRV---RKATQQAEQLSNELATERSTAQKN---- 1795
Query: 242 DAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVS-LTTQLEDTKRLADEEARERATLLGK 418
++A+++L +N +L +L E E V K ++ L ++ + ++EARE+
Sbjct: 1796 ESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKS 1855
Query: 419 FRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRK 598
+ + L I QVE+E + + Q K NA + + + E E S+ + +RK
Sbjct: 1856 LKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLE-EAEEESQRINANRRK 1914
Query: 599 LQARLAEAEETIESLNQKVVALEKTKQRLATE 694
LQ L EA E+ E++ ++V AL K+K R E
Sbjct: 1915 LQRELDEATESNEAMGREVNAL-KSKLRRGNE 1945
Score = 63.7 bits (148), Expect = 7e-10
Identities = 59/241 (24%), Positives = 108/241 (44%), Gaps = 8/241 (3%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDH-LSNEKAAQEKIVKQLQHQLNE 196
+ +M QL++L E + + + L+ + L E+ +QLQ QL+E
Sbjct: 1553 MEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHE 1612
Query: 197 VQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEA----ESQVSQLSKIKVSL---TTQ 355
+++ ++ + AAKKKL + DL Q + A E + QL K++ + +
Sbjct: 1613 YETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRE 1672
Query: 356 LEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLW 535
LED + DE K ++LE DL ++E + A +A Q L K +L
Sbjct: 1673 LEDARASRDEIFATAKENEKKAKSLEADLMQLQEDL--AAAERARKQADLEKEELAEEL- 1729
Query: 536 RSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLE 715
+ ++ L++ KR+L+AR+A+ EE +E + A+ ++ + E L E
Sbjct: 1730 -----ASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNE 1784
Query: 716 V 718
+
Sbjct: 1785 L 1785
Score = 62.9 bits (146), Expect = 1e-09
Identities = 58/233 (24%), Positives = 113/233 (48%), Gaps = 3/233 (1%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD 214
++L+Q + + + + +L A + + AA+++ +L+ L+E++++ +
Sbjct: 888 KELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQ---ELEEILHEMEARLE 944
Query: 215 EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADE--E 388
E L A +KK++ + DL QLEE E+ +L KV+ ++ K+L DE
Sbjct: 945 EEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKI---KKLEDEILV 1001
Query: 389 ARERATLLGKFRN-LEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVA 565
++ L K R LE + ++ + EE E +L + +K + + + E +
Sbjct: 1002 MDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKS 1061
Query: 566 RSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
R +ELE+ KRKL+ ++ E I L ++ L K +LA + E+LQ + R
Sbjct: 1062 R-QELEKLKRKLEGDASDFHEQIADLQAQIAEL---KMQLAKKEEELQAALAR 1110
Score = 56.0 bits (129), Expect = 1e-07
Identities = 53/245 (21%), Positives = 105/245 (42%), Gaps = 21/245 (8%)
Frame = +2
Query: 44 DQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEAN 223
DQ NKL K R ++DL L + K+ + + ++E++ + +
Sbjct: 1004 DQNNKLS----KERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEE 1059
Query: 224 RTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERA 403
++ +L+ K+KL + SD Q+ + ++Q+++L +L+ D+E ++
Sbjct: 1060 KSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKN 1119
Query: 404 TLLGKFR-------NLEHDLDNIREQVEEEAEGKADLQRQLS----------KANAEAQL 532
L K R +L+ DLD+ R + + K DL +L + A Q
Sbjct: 1120 NALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQE 1179
Query: 533 WRSKYESEGVARSEELEEAKRKLQARLAEAE----ETIESLNQKVVALEKTKQRLATEVE 700
R+K E E + L+E R +A++ E + +E L +++ ++ K L +
Sbjct: 1180 LRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQ 1239
Query: 701 DLQLE 715
L+ E
Sbjct: 1240 TLEKE 1244
Score = 56.0 bits (129), Expect = 1e-07
Identities = 50/235 (21%), Positives = 106/235 (45%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+SD+ E LD + KAEK + E+ L+ L+ + A Q+++ + + ++ +
Sbjct: 1132 ISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVL 1191
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
+ DE R+ +A +++ +++ + +L E Q+ Q + K +L + ++
Sbjct: 1192 KKALDEETRS---HEAQVQEMRQKHAQAVEELTE---QLEQFKRAKANLDKNKQTLEKEN 1245
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEG 559
+ A E L + +EH + QV+E +D +R ++ N + +++ ES
Sbjct: 1246 ADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESV- 1304
Query: 560 VARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
E E KL +A ++ + + E+T+Q+L + QLE +R
Sbjct: 1305 TGMLNEAEGKAIKLAKDVASLSSQLQDTQE--LLQEETRQKLNVSTKLRQLEEER 1357
Score = 53.2 bits (122), Expect = 1e-06
Identities = 44/200 (22%), Positives = 95/200 (47%), Gaps = 10/200 (5%)
Frame = +2
Query: 155 QEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLE-------EAESQ 313
QE+ ++ + +L + + + +A L +L+ +L+ E + L QL+ EAE
Sbjct: 862 QEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEM 921
Query: 314 VSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADL 493
+L+ K L L + + +EE L + + + + ++ EQ+EEE + L
Sbjct: 922 RVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKL 981
Query: 494 QRQLSKANAEAQLWRSKYESEGVA---RSEELEEAKRKLQARLAEAEETIESLNQKVVAL 664
QL K AEA++ K E E + ++ +L + ++ L+ R+++ + +K L
Sbjct: 982 --QLEKVTAEAKI--KKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNL 1037
Query: 665 EKTKQRLATEVEDLQLEVDR 724
K K + + + +L++ + +
Sbjct: 1038 TKLKNKHESMISELEVRLKK 1057
Score = 48.4 bits (110), Expect = 3e-05
Identities = 49/229 (21%), Positives = 100/229 (43%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD 214
E L + + +A+ + + E+ +G + L +EK E + QL+ +L E Q +
Sbjct: 1706 EDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNME 1765
Query: 215 EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEAR 394
+ + ++LS E + ++ ES QL + L ++L + + +++
Sbjct: 1766 AMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAV--KSK 1823
Query: 395 ERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSE 574
++T+ LE + + EQVE+EA K + L + + + + + E E +E
Sbjct: 1824 FKSTIAA----LEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDER-KMAE 1878
Query: 575 ELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
+ +E K AR+ + + +E E+ QR+ LQ E+D
Sbjct: 1879 QYKEQAEKGNARVKQLKRQLEEA-------EEESQRINANRRKLQRELD 1920
Score = 43.6 bits (98), Expect = 8e-04
Identities = 28/122 (22%), Positives = 55/122 (45%)
Frame = +2
Query: 59 LKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLND 238
+K+K + A +++ L ++ + EK A K +KQ +L E+ + ++ +
Sbjct: 1820 VKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQ 1879
Query: 239 LDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGK 418
+K + L RQLEEAE + +++ + L +L++ + RE L K
Sbjct: 1880 YKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSK 1939
Query: 419 FR 424
R
Sbjct: 1940 LR 1941
>Z82215-4|CAB05105.1| 1960|Homo sapiens myosin, heavy chain 9,
non-muscle protein.
Length = 1960
Score = 128 bits (310), Expect = 2e-29
Identities = 78/234 (33%), Positives = 130/234 (55%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
V ++ EQL+Q ++KA EK + +E +L + L K E K+++ QL E+
Sbjct: 1198 VEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQEL 1257
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
Q K +E R +L KL +E ++ L +++S+ S+L+K +L +QL+DT+ L
Sbjct: 1258 QVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELL 1317
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEG 559
EE R++ +L K + +E + ++ REQ+EEE E K +L++Q++ +A+ + K E +
Sbjct: 1318 QEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKME-DS 1376
Query: 560 VARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
V E EE KRKLQ L + E LEKTK RL E++DL +++D
Sbjct: 1377 VGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLD 1430
Score = 77.0 bits (181), Expect = 7e-14
Identities = 53/219 (24%), Positives = 104/219 (47%), Gaps = 1/219 (0%)
Frame = +2
Query: 68 KAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDA 247
K EK + + E++DL LDH EK K+ L E ++ + + + +A
Sbjct: 1410 KLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEA 1469
Query: 248 AKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRN 427
++ + L R LEEA Q ++L ++ T++ED D+ + L R
Sbjct: 1470 EAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRA 1529
Query: 428 LEHDLDNIREQVEE-EAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQ 604
LE ++ ++ Q+EE E E +A +L + Q ++++E + R E+ EE K++L
Sbjct: 1530 LEQQVEEMKTQLEELEDELQATEDAKL-RLEVNLQAMKAQFERDLQGRDEQSEEKKKQLV 1588
Query: 605 ARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
++ E E +E ++ +++L +++DL+ +D
Sbjct: 1589 RQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHID 1627
Score = 66.1 bits (154), Expect = 1e-10
Identities = 49/235 (20%), Positives = 105/235 (44%), Gaps = 1/235 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDH-LSNEKAAQEKIVKQLQHQLNE 196
V +M QL++L E + + + ++A + L E+ KQL Q+ E
Sbjct: 1534 VEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVRE 1593
Query: 197 VQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRL 376
++++ ++ + + AA+KKL ++ DL ++ A + K L Q++D R
Sbjct: 1594 MEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRE 1653
Query: 377 ADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESE 556
D+ R +L + + E L ++ ++ + E A +R +A E + +
Sbjct: 1654 LDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANS 1713
Query: 557 GVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
+ LEE KR+L+AR+A+ EE +E + ++ +++ + +++
Sbjct: 1714 SGKGALALEE-KRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLN 1767
Score = 64.9 bits (151), Expect = 3e-10
Identities = 55/240 (22%), Positives = 106/240 (44%), Gaps = 6/240 (2%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+ D E L + N+ K Q E N R L+ K EK + L Q+ ++
Sbjct: 1310 LQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADM 1369
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
+ K +++ L + K+KL + L ++ EE + +L K K L +L+D L
Sbjct: 1370 KKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDL--LV 1427
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYES-- 553
D + + ++ NLE + + EE A + +A AEA+ +K S
Sbjct: 1428 DLDHQRQSAC-----NLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLA 1482
Query: 554 ----EGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
E + + ELE ++ + + + + + + + V LEK+K+ L +VE+++ +++
Sbjct: 1483 RALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLE 1542
Score = 64.5 bits (150), Expect = 4e-10
Identities = 59/239 (24%), Positives = 117/239 (48%), Gaps = 12/239 (5%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD 214
EQL +L A+AE+ RA+ ++ +L L +E+ + LQ + ++Q
Sbjct: 887 EQLQAETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQ 946
Query: 215 EANRTLNDLDAAKKKLSIENSDL---LRQLEEA----ESQVSQLSKIKVSLTTQL-EDTK 370
E L + ++A++KL +E L++LEE E Q +L+K K L ++ E T
Sbjct: 947 ELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTT 1006
Query: 371 RLADEEARERATLLGKFRNL-EHDLDNIREQVEEEAEGKADLQ---RQLSKANAEAQLWR 538
L +EE E++ L K +N E + ++ E++ E + + +L+ R+L + +
Sbjct: 1007 NLTEEE--EKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQI 1064
Query: 539 SKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLE 715
++ +++ +L + + +LQA LA EE N + + + + +++ EDL+ E
Sbjct: 1065 AELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESE 1123
Score = 62.9 bits (146), Expect = 1e-09
Identities = 59/243 (24%), Positives = 114/243 (46%), Gaps = 13/243 (5%)
Frame = +2
Query: 14 RFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLN 193
R V +M +L+ K ++ A R + ++ DL A +D + + K +++LQ Q+
Sbjct: 1589 RQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMK 1648
Query: 194 EVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQ-LSKIKVSLTTQLEDTK 370
+ + D+ + ++ A K EN L+ +E Q+ + L+ + + ++
Sbjct: 1649 DCMRELDDTRASREEILAQAK----ENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERD 1704
Query: 371 RLADEEARER---ATLLGKFRNLEHDLDNIREQVEEEAEGKADL--------QRQLSKAN 517
LADE A A L + R LE + + E++EEE +G +L Q+ + N
Sbjct: 1705 ELADEIANSSGKGALALEEKRRLEARIAQLEEELEEE-QGNTELINDRLKKANLQIDQIN 1763
Query: 518 AEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIES-LNQKVVALEKTKQRLATE 694
+ L RS + AR ++LE ++L+ +L E E T++S + ALE +L +
Sbjct: 1764 TDLNLERSHAQKNENAR-QQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQ 1822
Query: 695 VED 703
+++
Sbjct: 1823 LDN 1825
Score = 59.7 bits (138), Expect = 1e-08
Identities = 47/200 (23%), Positives = 93/200 (46%), Gaps = 10/200 (5%)
Frame = +2
Query: 155 QEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKI 334
QE+ + + +L +V+ K A L +++ + +L E L QL+ ++ ++
Sbjct: 843 QEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEEL 902
Query: 335 KVSLTTQLEDTKRLAD------EEARERAT-LLGKFRNLEHDLDNIREQVEEEAEGKADL 493
+ LT + ++ + + EE ER L + + ++ ++ + EQ+EEE + L
Sbjct: 903 RARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKL 962
Query: 494 QRQLSKANAEAQLWRSKYESEGVARSEE---LEEAKRKLQARLAEAEETIESLNQKVVAL 664
QL K EA+L K E E + ++ L + K+ L+ R+AE + +K +L
Sbjct: 963 --QLEKVTTEAKL--KKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSL 1018
Query: 665 EKTKQRLATEVEDLQLEVDR 724
K K + + DL+ + R
Sbjct: 1019 AKLKNKHEAMITDLEERLRR 1038
Score = 57.6 bits (133), Expect = 5e-08
Identities = 67/256 (26%), Positives = 113/256 (44%), Gaps = 28/256 (10%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD 214
+Q +L K K E A++ + + + L+ K E ++ L+ +L + +
Sbjct: 985 DQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQ 1044
Query: 215 EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEAR 394
E +T ++KL +++DL Q+ E ++Q+++L +L+ +EEA
Sbjct: 1045 ELEKT-------RRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAA 1097
Query: 395 ERATLLGKFRNLEHDLDNIREQVEEE--AEGKADLQ-RQLSK--------------ANAE 523
++ L K R LE + ++E +E E + KA+ Q R L + + A
Sbjct: 1098 QKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAA 1157
Query: 524 AQLWRSKYESEGVARSEELEEAKRKLQARLAE--------AEETIESLNQ--KVVA-LEK 670
Q RSK E E + LEE + +A++ E EE E L Q +V A LEK
Sbjct: 1158 QQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEK 1217
Query: 671 TKQRLATEVEDLQLEV 718
KQ L E +L EV
Sbjct: 1218 AKQTLENERGELANEV 1233
Score = 54.0 bits (124), Expect = 6e-07
Identities = 44/222 (19%), Positives = 103/222 (46%), Gaps = 2/222 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+S++ E L+ + KAEK + E+ L+ L+ + AAQ+++ + + ++N +
Sbjct: 1113 ISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNIL 1172
Query: 200 QSKADEANRTLN-DLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRL 376
+ +E +T + ++K S +L QLE+ + + L K K +L + +
Sbjct: 1173 KKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANE 1232
Query: 377 ADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESE 556
+ + K + +E L ++ + E + +L +++K E S+
Sbjct: 1233 VKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLL-SQ 1291
Query: 557 GVARSEELEEAKRKLQARLAEAEETIESLNQKVVALE-KTKQ 679
++S +L + L+++L + +E ++ N++ ++L K KQ
Sbjct: 1292 SDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQ 1333
Score = 53.2 bits (122), Expect = 1e-06
Identities = 34/122 (27%), Positives = 57/122 (46%)
Frame = +2
Query: 59 LKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLND 238
+K+K + +++ L LD+ + E+ A K V++ + +L +V + D+ R
Sbjct: 1801 VKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQ 1860
Query: 239 LDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGK 418
K S L RQLEEAE + + + + L +LED AD RE ++L K
Sbjct: 1861 YKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKNK 1920
Query: 419 FR 424
R
Sbjct: 1921 LR 1922
Score = 51.2 bits (117), Expect = 4e-06
Identities = 48/230 (20%), Positives = 91/230 (39%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+ ++ EQL++ + K + + +++ L L ++ K K L+ ++ E
Sbjct: 945 IQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEF 1004
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
+ E L K K +DL +L E Q +L K + L D
Sbjct: 1005 TTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQI 1064
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEG 559
E + A L + E +L +VEEEA K +++ + ++ + ESE
Sbjct: 1065 AELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESER 1124
Query: 560 VARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQ 709
+R+ + E+ KR L L + +E A ++ + + EV L+
Sbjct: 1125 ASRN-KAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILK 1173
Score = 49.6 bits (113), Expect = 1e-05
Identities = 56/238 (23%), Positives = 102/238 (42%), Gaps = 22/238 (9%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD 214
++ D+L A + A E L A + L E ++ + + +L + + D
Sbjct: 1701 QERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQID 1760
Query: 215 EANRTLN-------DLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVS-LTTQLEDTK 370
+ N LN + A+++L +N +L +L+E E V K ++ L ++ +
Sbjct: 1761 QINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLE 1820
Query: 371 RLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEG------KAD--------LQRQLS 508
D E +ER + R E L ++ QV++E +AD L+RQL
Sbjct: 1821 EQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLE 1880
Query: 509 KANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQR 682
+A EAQ ++RKLQ L +A ET +++N++V +L+ +R
Sbjct: 1881 EAEEEAQ---------------RANASRRKLQRELEDATETADAMNREVSSLKNKLRR 1923
>CR456526-1|CAG30412.1| 1960|Homo sapiens MYH9 protein.
Length = 1960
Score = 128 bits (310), Expect = 2e-29
Identities = 78/234 (33%), Positives = 130/234 (55%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
V ++ EQL+Q ++KA EK + +E +L + L K E K+++ QL E+
Sbjct: 1198 VEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQEL 1257
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
Q K +E R +L KL +E ++ L +++S+ S+L+K +L +QL+DT+ L
Sbjct: 1258 QVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELL 1317
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEG 559
EE R++ +L K + +E + ++ REQ+EEE E K +L++Q++ +A+ + K E +
Sbjct: 1318 QEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKME-DS 1376
Query: 560 VARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
V E EE KRKLQ L + E LEKTK RL E++DL +++D
Sbjct: 1377 VGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLD 1430
Score = 77.0 bits (181), Expect = 7e-14
Identities = 53/219 (24%), Positives = 104/219 (47%), Gaps = 1/219 (0%)
Frame = +2
Query: 68 KAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDA 247
K EK + + E++DL LDH EK K+ L E ++ + + + +A
Sbjct: 1410 KLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEA 1469
Query: 248 AKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRN 427
++ + L R LEEA Q ++L ++ T++ED D+ + L R
Sbjct: 1470 EAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRA 1529
Query: 428 LEHDLDNIREQVEE-EAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQ 604
LE ++ ++ Q+EE E E +A +L + Q ++++E + R E+ EE K++L
Sbjct: 1530 LEQQVEEMKTQLEELEDELQATEDAKL-RLEVNLQAMKAQFERDLQGRDEQSEEKKKQLV 1588
Query: 605 ARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
++ E E +E ++ +++L +++DL+ +D
Sbjct: 1589 RQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHID 1627
Score = 66.1 bits (154), Expect = 1e-10
Identities = 49/235 (20%), Positives = 105/235 (44%), Gaps = 1/235 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDH-LSNEKAAQEKIVKQLQHQLNE 196
V +M QL++L E + + + ++A + L E+ KQL Q+ E
Sbjct: 1534 VEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVRE 1593
Query: 197 VQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRL 376
++++ ++ + + AA+KKL ++ DL ++ A + K L Q++D R
Sbjct: 1594 MEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRE 1653
Query: 377 ADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESE 556
D+ R +L + + E L ++ ++ + E A +R +A E + +
Sbjct: 1654 LDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANS 1713
Query: 557 GVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
+ LEE KR+L+AR+A+ EE +E + ++ +++ + +++
Sbjct: 1714 SGKGALALEE-KRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLN 1767
Score = 64.9 bits (151), Expect = 3e-10
Identities = 55/240 (22%), Positives = 106/240 (44%), Gaps = 6/240 (2%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+ D E L + N+ K Q E N R L+ K EK + L Q+ ++
Sbjct: 1310 LQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADM 1369
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
+ K +++ L + K+KL + L ++ EE + +L K K L +L+D L
Sbjct: 1370 KKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDL--LV 1427
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYES-- 553
D + + ++ NLE + + EE A + +A AEA+ +K S
Sbjct: 1428 DLDHQRQSAC-----NLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLA 1482
Query: 554 ----EGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
E + + ELE ++ + + + + + + + V LEK+K+ L +VE+++ +++
Sbjct: 1483 RALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLE 1542
Score = 64.5 bits (150), Expect = 4e-10
Identities = 59/239 (24%), Positives = 117/239 (48%), Gaps = 12/239 (5%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD 214
EQL +L A+AE+ RA+ ++ +L L +E+ + LQ + ++Q
Sbjct: 887 EQLQAETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQ 946
Query: 215 EANRTLNDLDAAKKKLSIENSDL---LRQLEEA----ESQVSQLSKIKVSLTTQL-EDTK 370
E L + ++A++KL +E L++LEE E Q +L+K K L ++ E T
Sbjct: 947 ELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTT 1006
Query: 371 RLADEEARERATLLGKFRNL-EHDLDNIREQVEEEAEGKADLQ---RQLSKANAEAQLWR 538
L +EE E++ L K +N E + ++ E++ E + + +L+ R+L + +
Sbjct: 1007 NLTEEE--EKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQI 1064
Query: 539 SKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLE 715
++ +++ +L + + +LQA LA EE N + + + + +++ EDL+ E
Sbjct: 1065 AELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESE 1123
Score = 62.9 bits (146), Expect = 1e-09
Identities = 59/243 (24%), Positives = 114/243 (46%), Gaps = 13/243 (5%)
Frame = +2
Query: 14 RFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLN 193
R V +M +L+ K ++ A R + ++ DL A +D + + K +++LQ Q+
Sbjct: 1589 RQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMK 1648
Query: 194 EVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQ-LSKIKVSLTTQLEDTK 370
+ + D+ + ++ A K EN L+ +E Q+ + L+ + + ++
Sbjct: 1649 DCMRELDDTRASREEILAQAK----ENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERD 1704
Query: 371 RLADEEARER---ATLLGKFRNLEHDLDNIREQVEEEAEGKADL--------QRQLSKAN 517
LADE A A L + R LE + + E++EEE +G +L Q+ + N
Sbjct: 1705 ELADEIANSSGKGALALEEKRRLEARIAQLEEELEEE-QGNTELINDRLKKANLQIDQIN 1763
Query: 518 AEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIES-LNQKVVALEKTKQRLATE 694
+ L RS + AR ++LE ++L+ +L E E T++S + ALE +L +
Sbjct: 1764 TDLNLERSHAQKNENAR-QQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQ 1822
Query: 695 VED 703
+++
Sbjct: 1823 LDN 1825
Score = 59.7 bits (138), Expect = 1e-08
Identities = 47/200 (23%), Positives = 93/200 (46%), Gaps = 10/200 (5%)
Frame = +2
Query: 155 QEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKI 334
QE+ + + +L +V+ K A L +++ + +L E L QL+ ++ ++
Sbjct: 843 QEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEEL 902
Query: 335 KVSLTTQLEDTKRLAD------EEARERAT-LLGKFRNLEHDLDNIREQVEEEAEGKADL 493
+ LT + ++ + + EE ER L + + ++ ++ + EQ+EEE + L
Sbjct: 903 RARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKL 962
Query: 494 QRQLSKANAEAQLWRSKYESEGVARSEE---LEEAKRKLQARLAEAEETIESLNQKVVAL 664
QL K EA+L K E E + ++ L + K+ L+ R+AE + +K +L
Sbjct: 963 --QLEKVTTEAKL--KKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSL 1018
Query: 665 EKTKQRLATEVEDLQLEVDR 724
K K + + DL+ + R
Sbjct: 1019 AKLKNKHEAMITDLEERLRR 1038
Score = 57.6 bits (133), Expect = 5e-08
Identities = 67/256 (26%), Positives = 113/256 (44%), Gaps = 28/256 (10%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD 214
+Q +L K K E A++ + + + L+ K E ++ L+ +L + +
Sbjct: 985 DQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQ 1044
Query: 215 EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEAR 394
E +T ++KL +++DL Q+ E ++Q+++L +L+ +EEA
Sbjct: 1045 ELEKT-------RRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAA 1097
Query: 395 ERATLLGKFRNLEHDLDNIREQVEEE--AEGKADLQ-RQLSK--------------ANAE 523
++ L K R LE + ++E +E E + KA+ Q R L + + A
Sbjct: 1098 QKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAA 1157
Query: 524 AQLWRSKYESEGVARSEELEEAKRKLQARLAE--------AEETIESLNQ--KVVA-LEK 670
Q RSK E E + LEE + +A++ E EE E L Q +V A LEK
Sbjct: 1158 QQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEK 1217
Query: 671 TKQRLATEVEDLQLEV 718
KQ L E +L EV
Sbjct: 1218 AKQTLENERGELANEV 1233
Score = 54.0 bits (124), Expect = 6e-07
Identities = 44/222 (19%), Positives = 103/222 (46%), Gaps = 2/222 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+S++ E L+ + KAEK + E+ L+ L+ + AAQ+++ + + ++N +
Sbjct: 1113 ISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNIL 1172
Query: 200 QSKADEANRTLN-DLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRL 376
+ +E +T + ++K S +L QLE+ + + L K K +L + +
Sbjct: 1173 KKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANE 1232
Query: 377 ADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESE 556
+ + K + +E L ++ + E + +L +++K E S+
Sbjct: 1233 VKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLL-SQ 1291
Query: 557 GVARSEELEEAKRKLQARLAEAEETIESLNQKVVALE-KTKQ 679
++S +L + L+++L + +E ++ N++ ++L K KQ
Sbjct: 1292 SDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQ 1333
Score = 53.2 bits (122), Expect = 1e-06
Identities = 34/122 (27%), Positives = 57/122 (46%)
Frame = +2
Query: 59 LKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLND 238
+K+K + +++ L LD+ + E+ A K V++ + +L +V + D+ R
Sbjct: 1801 VKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQ 1860
Query: 239 LDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGK 418
K S L RQLEEAE + + + + L +LED AD RE ++L K
Sbjct: 1861 YKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKNK 1920
Query: 419 FR 424
R
Sbjct: 1921 LR 1922
Score = 51.2 bits (117), Expect = 4e-06
Identities = 48/230 (20%), Positives = 91/230 (39%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+ ++ EQL++ + K + + +++ L L ++ K K L+ ++ E
Sbjct: 945 IQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEF 1004
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
+ E L K K +DL +L E Q +L K + L D
Sbjct: 1005 TTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQI 1064
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEG 559
E + A L + E +L +VEEEA K +++ + ++ + ESE
Sbjct: 1065 AELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESER 1124
Query: 560 VARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQ 709
+R+ + E+ KR L L + +E A ++ + + EV L+
Sbjct: 1125 ASRN-KAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILK 1173
Score = 49.6 bits (113), Expect = 1e-05
Identities = 56/238 (23%), Positives = 102/238 (42%), Gaps = 22/238 (9%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD 214
++ D+L A + A E L A + L E ++ + + +L + + D
Sbjct: 1701 QERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQID 1760
Query: 215 EANRTLN-------DLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVS-LTTQLEDTK 370
+ N LN + A+++L +N +L +L+E E V K ++ L ++ +
Sbjct: 1761 QINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLE 1820
Query: 371 RLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEG------KAD--------LQRQLS 508
D E +ER + R E L ++ QV++E +AD L+RQL
Sbjct: 1821 EQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLE 1880
Query: 509 KANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQR 682
+A EAQ ++RKLQ L +A ET +++N++V +L+ +R
Sbjct: 1881 EAEEEAQ---------------RANASRRKLQRELEDATETADAMNREVSSLKNKLRR 1923
>AB191263-1|BAD52439.1| 1960|Homo sapiens non-muscle myosin heavy
polypeptide 9 protein.
Length = 1960
Score = 128 bits (310), Expect = 2e-29
Identities = 78/234 (33%), Positives = 130/234 (55%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
V ++ EQL+Q ++KA EK + +E +L + L K E K+++ QL E+
Sbjct: 1198 VEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQEL 1257
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
Q K +E R +L KL +E ++ L +++S+ S+L+K +L +QL+DT+ L
Sbjct: 1258 QVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELL 1317
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEG 559
EE R++ +L K + +E + ++ REQ+EEE E K +L++Q++ +A+ + K E +
Sbjct: 1318 QEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKME-DS 1376
Query: 560 VARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
V E EE KRKLQ L + E LEKTK RL E++DL +++D
Sbjct: 1377 VGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLD 1430
Score = 77.0 bits (181), Expect = 7e-14
Identities = 53/219 (24%), Positives = 104/219 (47%), Gaps = 1/219 (0%)
Frame = +2
Query: 68 KAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDA 247
K EK + + E++DL LDH EK K+ L E ++ + + + +A
Sbjct: 1410 KLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEA 1469
Query: 248 AKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRN 427
++ + L R LEEA Q ++L ++ T++ED D+ + L R
Sbjct: 1470 EAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRA 1529
Query: 428 LEHDLDNIREQVEE-EAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQ 604
LE ++ ++ Q+EE E E +A +L + Q ++++E + R E+ EE K++L
Sbjct: 1530 LEQQVEEMKTQLEELEDELQATEDAKL-RLEVNLQAMKAQFERDLQGRDEQSEEKKKQLV 1588
Query: 605 ARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
++ E E +E ++ +++L +++DL+ +D
Sbjct: 1589 RQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHID 1627
Score = 66.1 bits (154), Expect = 1e-10
Identities = 49/235 (20%), Positives = 105/235 (44%), Gaps = 1/235 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDH-LSNEKAAQEKIVKQLQHQLNE 196
V +M QL++L E + + + ++A + L E+ KQL Q+ E
Sbjct: 1534 VEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVRE 1593
Query: 197 VQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRL 376
++++ ++ + + AA+KKL ++ DL ++ A + K L Q++D R
Sbjct: 1594 MEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRE 1653
Query: 377 ADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESE 556
D+ R +L + + E L ++ ++ + E A +R +A E + +
Sbjct: 1654 LDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANS 1713
Query: 557 GVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
+ LEE KR+L+AR+A+ EE +E + ++ +++ + +++
Sbjct: 1714 SGKGALALEE-KRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLN 1767
Score = 64.9 bits (151), Expect = 3e-10
Identities = 55/240 (22%), Positives = 106/240 (44%), Gaps = 6/240 (2%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+ D E L + N+ K Q E N R L+ K EK + L Q+ ++
Sbjct: 1310 LQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADM 1369
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
+ K +++ L + K+KL + L ++ EE + +L K K L +L+D L
Sbjct: 1370 KKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDL--LV 1427
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYES-- 553
D + + ++ NLE + + EE A + +A AEA+ +K S
Sbjct: 1428 DLDHQRQSAC-----NLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLA 1482
Query: 554 ----EGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
E + + ELE ++ + + + + + + + V LEK+K+ L +VE+++ +++
Sbjct: 1483 RALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLE 1542
Score = 64.5 bits (150), Expect = 4e-10
Identities = 59/239 (24%), Positives = 117/239 (48%), Gaps = 12/239 (5%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD 214
EQL +L A+AE+ RA+ ++ +L L +E+ + LQ + ++Q
Sbjct: 887 EQLQAETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQ 946
Query: 215 EANRTLNDLDAAKKKLSIENSDL---LRQLEEA----ESQVSQLSKIKVSLTTQL-EDTK 370
E L + ++A++KL +E L++LEE E Q +L+K K L ++ E T
Sbjct: 947 ELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTT 1006
Query: 371 RLADEEARERATLLGKFRNL-EHDLDNIREQVEEEAEGKADLQ---RQLSKANAEAQLWR 538
L +EE E++ L K +N E + ++ E++ E + + +L+ R+L + +
Sbjct: 1007 NLTEEE--EKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQI 1064
Query: 539 SKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLE 715
++ +++ +L + + +LQA LA EE N + + + + +++ EDL+ E
Sbjct: 1065 AELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESE 1123
Score = 62.9 bits (146), Expect = 1e-09
Identities = 59/243 (24%), Positives = 114/243 (46%), Gaps = 13/243 (5%)
Frame = +2
Query: 14 RFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLN 193
R V +M +L+ K ++ A R + ++ DL A +D + + K +++LQ Q+
Sbjct: 1589 RQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMK 1648
Query: 194 EVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQ-LSKIKVSLTTQLEDTK 370
+ + D+ + ++ A K EN L+ +E Q+ + L+ + + ++
Sbjct: 1649 DCMRELDDTRASREEILAQAK----ENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERD 1704
Query: 371 RLADEEARER---ATLLGKFRNLEHDLDNIREQVEEEAEGKADL--------QRQLSKAN 517
LADE A A L + R LE + + E++EEE +G +L Q+ + N
Sbjct: 1705 ELADEIANSSGKGALALEEKRRLEARIAQLEEELEEE-QGNTELINDRLKKANLQIDQIN 1763
Query: 518 AEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIES-LNQKVVALEKTKQRLATE 694
+ L RS + AR ++LE ++L+ +L E E T++S + ALE +L +
Sbjct: 1764 TDLNLERSHAQKNENAR-QQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQ 1822
Query: 695 VED 703
+++
Sbjct: 1823 LDN 1825
Score = 59.7 bits (138), Expect = 1e-08
Identities = 47/200 (23%), Positives = 93/200 (46%), Gaps = 10/200 (5%)
Frame = +2
Query: 155 QEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKI 334
QE+ + + +L +V+ K A L +++ + +L E L QL+ ++ ++
Sbjct: 843 QEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEEL 902
Query: 335 KVSLTTQLEDTKRLAD------EEARERAT-LLGKFRNLEHDLDNIREQVEEEAEGKADL 493
+ LT + ++ + + EE ER L + + ++ ++ + EQ+EEE + L
Sbjct: 903 RARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKL 962
Query: 494 QRQLSKANAEAQLWRSKYESEGVARSEE---LEEAKRKLQARLAEAEETIESLNQKVVAL 664
QL K EA+L K E E + ++ L + K+ L+ R+AE + +K +L
Sbjct: 963 --QLEKVTTEAKL--KKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSL 1018
Query: 665 EKTKQRLATEVEDLQLEVDR 724
K K + + DL+ + R
Sbjct: 1019 AKLKNKHEAMITDLEERLRR 1038
Score = 57.6 bits (133), Expect = 5e-08
Identities = 67/256 (26%), Positives = 113/256 (44%), Gaps = 28/256 (10%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD 214
+Q +L K K E A++ + + + L+ K E ++ L+ +L + +
Sbjct: 985 DQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQ 1044
Query: 215 EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEAR 394
E +T ++KL +++DL Q+ E ++Q+++L +L+ +EEA
Sbjct: 1045 ELEKT-------RRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAA 1097
Query: 395 ERATLLGKFRNLEHDLDNIREQVEEE--AEGKADLQ-RQLSK--------------ANAE 523
++ L K R LE + ++E +E E + KA+ Q R L + + A
Sbjct: 1098 QKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAA 1157
Query: 524 AQLWRSKYESEGVARSEELEEAKRKLQARLAE--------AEETIESLNQ--KVVA-LEK 670
Q RSK E E + LEE + +A++ E EE E L Q +V A LEK
Sbjct: 1158 QQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEK 1217
Query: 671 TKQRLATEVEDLQLEV 718
KQ L E +L EV
Sbjct: 1218 AKQTLENERGELANEV 1233
Score = 54.0 bits (124), Expect = 6e-07
Identities = 44/222 (19%), Positives = 103/222 (46%), Gaps = 2/222 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+S++ E L+ + KAEK + E+ L+ L+ + AAQ+++ + + ++N +
Sbjct: 1113 ISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNIL 1172
Query: 200 QSKADEANRTLN-DLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRL 376
+ +E +T + ++K S +L QLE+ + + L K K +L + +
Sbjct: 1173 KKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANE 1232
Query: 377 ADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESE 556
+ + K + +E L ++ + E + +L +++K E S+
Sbjct: 1233 VKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLL-SQ 1291
Query: 557 GVARSEELEEAKRKLQARLAEAEETIESLNQKVVALE-KTKQ 679
++S +L + L+++L + +E ++ N++ ++L K KQ
Sbjct: 1292 SDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQ 1333
Score = 53.2 bits (122), Expect = 1e-06
Identities = 34/122 (27%), Positives = 57/122 (46%)
Frame = +2
Query: 59 LKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLND 238
+K+K + +++ L LD+ + E+ A K V++ + +L +V + D+ R
Sbjct: 1801 VKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQ 1860
Query: 239 LDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGK 418
K S L RQLEEAE + + + + L +LED AD RE ++L K
Sbjct: 1861 YKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKNK 1920
Query: 419 FR 424
R
Sbjct: 1921 LR 1922
Score = 51.2 bits (117), Expect = 4e-06
Identities = 48/230 (20%), Positives = 91/230 (39%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+ ++ EQL++ + K + + +++ L L ++ K K L+ ++ E
Sbjct: 945 IQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEF 1004
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
+ E L K K +DL +L E Q +L K + L D
Sbjct: 1005 TTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQI 1064
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEG 559
E + A L + E +L +VEEEA K +++ + ++ + ESE
Sbjct: 1065 AELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESER 1124
Query: 560 VARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQ 709
+R+ + E+ KR L L + +E A ++ + + EV L+
Sbjct: 1125 ASRN-KAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILK 1173
Score = 49.6 bits (113), Expect = 1e-05
Identities = 56/238 (23%), Positives = 102/238 (42%), Gaps = 22/238 (9%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD 214
++ D+L A + A E L A + L E ++ + + +L + + D
Sbjct: 1701 QERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQID 1760
Query: 215 EANRTLN-------DLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVS-LTTQLEDTK 370
+ N LN + A+++L +N +L +L+E E V K ++ L ++ +
Sbjct: 1761 QINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLE 1820
Query: 371 RLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEG------KAD--------LQRQLS 508
D E +ER + R E L ++ QV++E +AD L+RQL
Sbjct: 1821 EQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLE 1880
Query: 509 KANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQR 682
+A EAQ ++RKLQ L +A ET +++N++V +L+ +R
Sbjct: 1881 EAEEEAQ---------------RANASRRKLQRELEDATETADAMNREVSSLKNKLRR 1923
>M69181-1|AAA99177.1| 1976|Homo sapiens non-muscle myosin B protein.
Length = 1976
Score = 127 bits (306), Expect = 5e-29
Identities = 78/237 (32%), Positives = 131/237 (55%), Gaps = 3/237 (1%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+ ++ EQL+Q + KA EK + ++ +L + L KA E K+L Q+ E+
Sbjct: 1205 LEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQEL 1264
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
+K E +R +L KL E ++ LEEAE + + +K SL +QL+DT+ L
Sbjct: 1265 HAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELL 1324
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEG 559
EE R++ L + R LE + ++++EQ EEE E + +L++Q+ ++ + K + +
Sbjct: 1325 QEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDD- 1383
Query: 560 VARSEELEEAKRKLQARLAEAEETIESLNQKVVA---LEKTKQRLATEVEDLQLEVD 721
+ E LEEAK+KL L +AE + L +K +A LEKTK RL E++DL +++D
Sbjct: 1384 LGTIESLEEAKKKL---LKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLD 1437
Score = 74.5 bits (175), Expect = 4e-13
Identities = 65/243 (26%), Positives = 109/243 (44%), Gaps = 22/243 (9%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+ + E+L + + AE+ R + E+ + +G L +EK E + QL+ +L E
Sbjct: 1689 ILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEE 1748
Query: 200 QSKADEANR----------TLN-----------DLDAAKKKLSIENSDLLRQLEEAESQV 316
QS + N TLN D A+++L +N +L +L+E E V
Sbjct: 1749 QSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAV 1808
Query: 317 SQLSKIKVS-LTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADL 493
K +S L ++ + ++EA+ERA R E L I QVE+E
Sbjct: 1809 KSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQY 1868
Query: 494 QRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKT 673
+ Q+ KANA + + + E E + ++RKLQ L +A E E L+++V L+
Sbjct: 1869 KEQMEKANARMKQLKRQLE-EAEEEATRANASRRKLQRELDDATEANEGLSREVSTLKNR 1927
Query: 674 KQR 682
+R
Sbjct: 1928 LRR 1930
Score = 72.1 bits (169), Expect = 2e-12
Identities = 56/234 (23%), Positives = 105/234 (44%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+ D E L + + K Q E N L+ + + EK V LQ QL +
Sbjct: 1317 LQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADT 1376
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
+ K D+ T+ L+ AKKKL + L ++LEE +L K K L +L+D
Sbjct: 1377 KKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDL 1436
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEG 559
D + + + L K + + L + AE + + + + +A L ++ E
Sbjct: 1437 DHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKA-LSLARALEEA 1495
Query: 560 VARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
+ EE E ++L+A + + + + + + V LEK+K+ L +VE+++ +++
Sbjct: 1496 LEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLE 1549
Score = 70.9 bits (166), Expect = 5e-12
Identities = 54/232 (23%), Positives = 106/232 (45%), Gaps = 1/232 (0%)
Frame = +2
Query: 29 MGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSK 208
+ ++L++ K EK + + E++DL LDH + EK K+ L E +S
Sbjct: 1404 LSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSI 1463
Query: 209 ADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEE 388
+ + +A ++ + L R LEEA + + L +ED D+
Sbjct: 1464 SARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDV 1523
Query: 389 ARERATLLGKFRNLEHDLDNIREQVEE-EAEGKADLQRQLSKANAEAQLWRSKYESEGVA 565
+ L R LE ++ +R Q+EE E E +A +L + Q ++++E +
Sbjct: 1524 GKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKL-RLEVNMQAMKAQFERDLQT 1582
Query: 566 RSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
R E+ EE KR L ++ E E +E ++ +K+++ +++DL+ +++
Sbjct: 1583 RDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIE 1634
Score = 68.9 bits (161), Expect = 2e-11
Identities = 52/234 (22%), Positives = 105/234 (44%), Gaps = 1/234 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDH-LSNEKAAQEKIVKQLQHQLNE 196
V +M QL++L E + + + ++A + L E+ + L Q+ E
Sbjct: 1541 VEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRE 1600
Query: 197 VQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRL 376
++++ ++ + A+KKK+ I+ DL Q+E A ++ K L Q++D +R
Sbjct: 1601 LEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRE 1660
Query: 377 ADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESE 556
+E R + + + E L ++ ++ + E A +R A E + +
Sbjct: 1661 LEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNS 1720
Query: 557 GVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEV 718
+S L+E KR+L+AR+A+ EE +E + L ++ +V+ L E+
Sbjct: 1721 ASGKSALLDE-KRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAEL 1773
Score = 60.1 bits (139), Expect = 9e-09
Identities = 52/225 (23%), Positives = 105/225 (46%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD 214
+QL + + A+ + + F+E ++RA L AA+++ ++++ H L + +
Sbjct: 883 QQLLEEKNILAEQLQAETELFAEAEEMRARL-------AAKKQELEEILHDLESRVEEEE 935
Query: 215 EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEAR 394
E N+ L + KKK+ DL QL+E E +L KV+ +++ +
Sbjct: 936 ERNQILQN---EKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLED 992
Query: 395 ERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSE 574
+ + + + + +E + Q+ EE E +L + +K + + E R +
Sbjct: 993 QNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTR-Q 1051
Query: 575 ELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQ 709
ELE+AKRKL + ++ I L ++ ++ K +LA + E+LQ
Sbjct: 1052 ELEKAKRKLDGETTDLQDQIAELQAQI---DELKLQLAKKEEELQ 1093
Score = 57.6 bits (133), Expect = 5e-08
Identities = 53/232 (22%), Positives = 107/232 (46%), Gaps = 3/232 (1%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD 214
E + QL KL+A+ + Y E+ + RA D + + EK +K L+ ++ ++Q +
Sbjct: 1642 EVIKQLRKLQAQMK----DYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELA 1697
Query: 215 EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEAR 394
+ R A++ E +L ++ + S S L K L ++ + +EE
Sbjct: 1698 SSER-------ARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQS 1750
Query: 395 ERATLLGKFRNLEHDLDNIREQV--EEEAEGKAD-LQRQLSKANAEAQLWRSKYESEGVA 565
L +FR +D + ++ E A K+D ++QL + N E L E EG
Sbjct: 1751 NMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKE--LKAKLQELEGAV 1808
Query: 566 RSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
+S + + L+A++ + EE +E ++ A K +R +++++ ++V+
Sbjct: 1809 KS-KFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVE 1859
Score = 54.8 bits (126), Expect = 3e-07
Identities = 47/195 (24%), Positives = 93/195 (47%), Gaps = 10/195 (5%)
Frame = +2
Query: 155 QEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLE-------EAESQ 313
QE+ ++ +L +V+ K + L +++ ++L E + L QL+ EAE
Sbjct: 850 QEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEM 909
Query: 314 VSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADL 493
++L+ K L L D + +EE L + + ++ + ++ EQ++EE EG A
Sbjct: 910 RARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEE-EG-ARQ 967
Query: 494 QRQLSKANAEAQLWRSKYESEGVA---RSEELEEAKRKLQARLAEAEETIESLNQKVVAL 664
+ QL K AEA++ K E E + ++ + + K+ ++ R+AE + +K L
Sbjct: 968 KLQLEKVTAEAKI--KKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNL 1025
Query: 665 EKTKQRLATEVEDLQ 709
K + + + DL+
Sbjct: 1026 AKIRNKQEVMISDLE 1040
Score = 49.6 bits (113), Expect = 1e-05
Identities = 51/238 (21%), Positives = 107/238 (44%), Gaps = 10/238 (4%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
++++ E + + KAEK + E+ L+ L+ + AAQ+++ + + ++ E+
Sbjct: 1120 IAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAEL 1179
Query: 200 QSKADEANRTLN-DLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRL 376
+ +E + + +++ + +L QLE+A+ + L K K L T D K L
Sbjct: 1180 KKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLET---DNKEL 1236
Query: 377 ADEE---ARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAE---AQLWR 538
A E + +A K + L+ + + +V E + +L + SK E
Sbjct: 1237 ACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLL 1296
Query: 539 SKYESEGVARSEELEEAKRKLQ-ARLAEAEETIESLN--QKVVALEKTKQRLATEVED 703
+ E +G+ +++ + +LQ + EET + LN ++ LE+ K L + E+
Sbjct: 1297 EEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEE 1354
Score = 47.6 bits (108), Expect = 5e-05
Identities = 51/240 (21%), Positives = 113/240 (47%), Gaps = 7/240 (2%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
V+ E+L ++ K ++ + + E+ ++ L EK + +QLQ + E+
Sbjct: 847 VTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNI---LAEQLQAE-TEL 902
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
++A+E L A K++L DL ++EE E + L K + ++D +
Sbjct: 903 FAEAEEMRARLA---AKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQL 959
Query: 380 DEE--AR-----ERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWR 538
DEE AR E+ T K + +E ++ + +Q + + K ++ ++++ +++
Sbjct: 960 DEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQL---- 1015
Query: 539 SKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEV 718
+E +++ L + + K + +++ EE ++ + LEK K++L E DLQ ++
Sbjct: 1016 ----AEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQI 1071
Score = 40.7 bits (91), Expect = 0.006
Identities = 25/97 (25%), Positives = 42/97 (43%)
Frame = +2
Query: 53 NKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTL 232
NKL + EK + F +V D R D + +KQL+ QL E + +A AN +
Sbjct: 1841 NKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASR 1900
Query: 233 NDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVS 343
L + N L R++ ++++ + I S
Sbjct: 1901 RKLQRELDDATEANEGLSREVSTLKNRLRRGGPISFS 1937
>BC117691-1|AAI17692.1| 1976|Homo sapiens myosin, heavy chain 10,
non-muscle protein.
Length = 1976
Score = 127 bits (306), Expect = 5e-29
Identities = 78/237 (32%), Positives = 131/237 (55%), Gaps = 3/237 (1%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+ ++ EQL+Q + KA EK + ++ +L + L KA E K+L Q+ E+
Sbjct: 1205 LEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQEL 1264
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
+K E +R +L KL E ++ LEEAE + + +K SL +QL+DT+ L
Sbjct: 1265 HAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELL 1324
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEG 559
EE R++ L + R LE + ++++EQ EEE E + +L++Q+ ++ + K + +
Sbjct: 1325 QEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDD- 1383
Query: 560 VARSEELEEAKRKLQARLAEAEETIESLNQKVVA---LEKTKQRLATEVEDLQLEVD 721
+ E LEEAK+KL L +AE + L +K +A LEKTK RL E++DL +++D
Sbjct: 1384 LGTIESLEEAKKKL---LKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLD 1437
Score = 74.5 bits (175), Expect = 4e-13
Identities = 65/243 (26%), Positives = 109/243 (44%), Gaps = 22/243 (9%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+ + E+L + + AE+ R + E+ + +G L +EK E + QL+ +L E
Sbjct: 1689 ILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEE 1748
Query: 200 QSKADEANR----------TLN-----------DLDAAKKKLSIENSDLLRQLEEAESQV 316
QS + N TLN D A+++L +N +L +L+E E V
Sbjct: 1749 QSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAV 1808
Query: 317 SQLSKIKVS-LTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADL 493
K +S L ++ + ++EA+ERA R E L I QVE+E
Sbjct: 1809 KSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQY 1868
Query: 494 QRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKT 673
+ Q+ KANA + + + E E + ++RKLQ L +A E E L+++V L+
Sbjct: 1869 KEQMEKANARMKQLKRQLE-EAEEEATRANASRRKLQRELDDATEANEGLSREVSTLKNR 1927
Query: 674 KQR 682
+R
Sbjct: 1928 LRR 1930
Score = 72.1 bits (169), Expect = 2e-12
Identities = 56/234 (23%), Positives = 105/234 (44%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+ D E L + + K Q E N L+ + + EK V LQ QL +
Sbjct: 1317 LQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADT 1376
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
+ K D+ T+ L+ AKKKL + L ++LEE +L K K L +L+D
Sbjct: 1377 KKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDL 1436
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEG 559
D + + + L K + + L + AE + + + + +A L ++ E
Sbjct: 1437 DHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKA-LSLARALEEA 1495
Query: 560 VARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
+ EE E ++L+A + + + + + + V LEK+K+ L +VE+++ +++
Sbjct: 1496 LEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLE 1549
Score = 70.9 bits (166), Expect = 5e-12
Identities = 54/232 (23%), Positives = 106/232 (45%), Gaps = 1/232 (0%)
Frame = +2
Query: 29 MGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSK 208
+ ++L++ K EK + + E++DL LDH + EK K+ L E +S
Sbjct: 1404 LSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSI 1463
Query: 209 ADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEE 388
+ + +A ++ + L R LEEA + + L +ED D+
Sbjct: 1464 SARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDV 1523
Query: 389 ARERATLLGKFRNLEHDLDNIREQVEE-EAEGKADLQRQLSKANAEAQLWRSKYESEGVA 565
+ L R LE ++ +R Q+EE E E +A +L + Q ++++E +
Sbjct: 1524 GKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKL-RLEVNMQAMKAQFERDLQT 1582
Query: 566 RSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
R E+ EE KR L ++ E E +E ++ +K+++ +++DL+ +++
Sbjct: 1583 RDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIE 1634
Score = 68.9 bits (161), Expect = 2e-11
Identities = 52/234 (22%), Positives = 105/234 (44%), Gaps = 1/234 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDH-LSNEKAAQEKIVKQLQHQLNE 196
V +M QL++L E + + + ++A + L E+ + L Q+ E
Sbjct: 1541 VEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRE 1600
Query: 197 VQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRL 376
++++ ++ + A+KKK+ I+ DL Q+E A ++ K L Q++D +R
Sbjct: 1601 LEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRE 1660
Query: 377 ADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESE 556
+E R + + + E L ++ ++ + E A +R A E + +
Sbjct: 1661 LEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNS 1720
Query: 557 GVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEV 718
+S L+E KR+L+AR+A+ EE +E + L ++ +V+ L E+
Sbjct: 1721 ASGKSALLDE-KRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAEL 1773
Score = 60.1 bits (139), Expect = 9e-09
Identities = 52/225 (23%), Positives = 105/225 (46%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD 214
+QL + + A+ + + F+E ++RA L AA+++ ++++ H L + +
Sbjct: 883 QQLLEEKNILAEQLQAETELFAEAEEMRARL-------AAKKQELEEILHDLESRVEEEE 935
Query: 215 EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEAR 394
E N+ L + KKK+ DL QL+E E +L KV+ +++ +
Sbjct: 936 ERNQILQN---EKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLED 992
Query: 395 ERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSE 574
+ + + + + +E + Q+ EE E +L + +K + + E R +
Sbjct: 993 QNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTR-Q 1051
Query: 575 ELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQ 709
ELE+AKRKL + ++ I L ++ ++ K +LA + E+LQ
Sbjct: 1052 ELEKAKRKLDGETTDLQDQIAELQAQI---DELKLQLAKKEEELQ 1093
Score = 57.6 bits (133), Expect = 5e-08
Identities = 53/232 (22%), Positives = 107/232 (46%), Gaps = 3/232 (1%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD 214
E + QL KL+A+ + Y E+ + RA D + + EK +K L+ ++ ++Q +
Sbjct: 1642 EVIKQLRKLQAQMK----DYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELA 1697
Query: 215 EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEAR 394
+ R A++ E +L ++ + S S L K L ++ + +EE
Sbjct: 1698 SSER-------ARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQS 1750
Query: 395 ERATLLGKFRNLEHDLDNIREQV--EEEAEGKAD-LQRQLSKANAEAQLWRSKYESEGVA 565
L +FR +D + ++ E A K+D ++QL + N E L E EG
Sbjct: 1751 NMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKE--LKAKLQELEGAV 1808
Query: 566 RSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
+S + + L+A++ + EE +E ++ A K +R +++++ ++V+
Sbjct: 1809 KS-KFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVE 1859
Score = 54.8 bits (126), Expect = 3e-07
Identities = 47/195 (24%), Positives = 93/195 (47%), Gaps = 10/195 (5%)
Frame = +2
Query: 155 QEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLE-------EAESQ 313
QE+ ++ +L +V+ K + L +++ ++L E + L QL+ EAE
Sbjct: 850 QEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEM 909
Query: 314 VSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADL 493
++L+ K L L D + +EE L + + ++ + ++ EQ++EE EG A
Sbjct: 910 RARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEE-EG-ARQ 967
Query: 494 QRQLSKANAEAQLWRSKYESEGVA---RSEELEEAKRKLQARLAEAEETIESLNQKVVAL 664
+ QL K AEA++ K E E + ++ + + K+ ++ R+AE + +K L
Sbjct: 968 KLQLEKVTAEAKI--KKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNL 1025
Query: 665 EKTKQRLATEVEDLQ 709
K + + + DL+
Sbjct: 1026 AKIRNKQEVMISDLE 1040
Score = 49.6 bits (113), Expect = 1e-05
Identities = 51/238 (21%), Positives = 107/238 (44%), Gaps = 10/238 (4%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
++++ E + + KAEK + E+ L+ L+ + AAQ+++ + + ++ E+
Sbjct: 1120 IAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAEL 1179
Query: 200 QSKADEANRTLN-DLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRL 376
+ +E + + +++ + +L QLE+A+ + L K K L T D K L
Sbjct: 1180 KKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLET---DNKEL 1236
Query: 377 ADEE---ARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAE---AQLWR 538
A E + +A K + L+ + + +V E + +L + SK E
Sbjct: 1237 ACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLL 1296
Query: 539 SKYESEGVARSEELEEAKRKLQ-ARLAEAEETIESLN--QKVVALEKTKQRLATEVED 703
+ E +G+ +++ + +LQ + EET + LN ++ LE+ K L + E+
Sbjct: 1297 EEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEE 1354
Score = 47.6 bits (108), Expect = 5e-05
Identities = 51/240 (21%), Positives = 113/240 (47%), Gaps = 7/240 (2%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
V+ E+L ++ K ++ + + E+ ++ L EK + +QLQ + E+
Sbjct: 847 VTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNI---LAEQLQAE-TEL 902
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
++A+E L A K++L DL ++EE E + L K + ++D +
Sbjct: 903 FAEAEEMRARLA---AKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQL 959
Query: 380 DEE--AR-----ERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWR 538
DEE AR E+ T K + +E ++ + +Q + + K ++ ++++ +++
Sbjct: 960 DEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQL---- 1015
Query: 539 SKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEV 718
+E +++ L + + K + +++ EE ++ + LEK K++L E DLQ ++
Sbjct: 1016 ----AEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQI 1071
Score = 40.7 bits (91), Expect = 0.006
Identities = 25/97 (25%), Positives = 42/97 (43%)
Frame = +2
Query: 53 NKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTL 232
NKL + EK + F +V D R D + +KQL+ QL E + +A AN +
Sbjct: 1841 NKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASR 1900
Query: 233 NDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVS 343
L + N L R++ ++++ + I S
Sbjct: 1901 RKLQRELDDATEANEGLSREVSTLKNRLRRGGPISFS 1937
>AB210026-1|BAE06108.1| 2018|Homo sapiens MYH10 variant protein
protein.
Length = 2018
Score = 127 bits (306), Expect = 5e-29
Identities = 78/237 (32%), Positives = 131/237 (55%), Gaps = 3/237 (1%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+ ++ EQL+Q + KA EK + ++ +L + L KA E K+L Q+ E+
Sbjct: 1247 LEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQEL 1306
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
+K E +R +L KL E ++ LEEAE + + +K SL +QL+DT+ L
Sbjct: 1307 HAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELL 1366
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEG 559
EE R++ L + R LE + ++++EQ EEE E + +L++Q+ ++ + K + +
Sbjct: 1367 QEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDD- 1425
Query: 560 VARSEELEEAKRKLQARLAEAEETIESLNQKVVA---LEKTKQRLATEVEDLQLEVD 721
+ E LEEAK+KL L +AE + L +K +A LEKTK RL E++DL +++D
Sbjct: 1426 LGTIESLEEAKKKL---LKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLD 1479
Score = 74.5 bits (175), Expect = 4e-13
Identities = 65/243 (26%), Positives = 109/243 (44%), Gaps = 22/243 (9%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+ + E+L + + AE+ R + E+ + +G L +EK E + QL+ +L E
Sbjct: 1731 ILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEE 1790
Query: 200 QSKADEANR----------TLN-----------DLDAAKKKLSIENSDLLRQLEEAESQV 316
QS + N TLN D A+++L +N +L +L+E E V
Sbjct: 1791 QSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAV 1850
Query: 317 SQLSKIKVS-LTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADL 493
K +S L ++ + ++EA+ERA R E L I QVE+E
Sbjct: 1851 KSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQY 1910
Query: 494 QRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKT 673
+ Q+ KANA + + + E E + ++RKLQ L +A E E L+++V L+
Sbjct: 1911 KEQMEKANARMKQLKRQLE-EAEEEATRANASRRKLQRELDDATEANEGLSREVSTLKNR 1969
Query: 674 KQR 682
+R
Sbjct: 1970 LRR 1972
Score = 72.1 bits (169), Expect = 2e-12
Identities = 56/234 (23%), Positives = 105/234 (44%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+ D E L + + K Q E N L+ + + EK V LQ QL +
Sbjct: 1359 LQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADT 1418
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
+ K D+ T+ L+ AKKKL + L ++LEE +L K K L +L+D
Sbjct: 1419 KKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDL 1478
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEG 559
D + + + L K + + L + AE + + + + +A L ++ E
Sbjct: 1479 DHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKA-LSLARALEEA 1537
Query: 560 VARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
+ EE E ++L+A + + + + + + V LEK+K+ L +VE+++ +++
Sbjct: 1538 LEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLE 1591
Score = 70.9 bits (166), Expect = 5e-12
Identities = 54/232 (23%), Positives = 106/232 (45%), Gaps = 1/232 (0%)
Frame = +2
Query: 29 MGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSK 208
+ ++L++ K EK + + E++DL LDH + EK K+ L E +S
Sbjct: 1446 LSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSI 1505
Query: 209 ADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEE 388
+ + +A ++ + L R LEEA + + L +ED D+
Sbjct: 1506 SARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDV 1565
Query: 389 ARERATLLGKFRNLEHDLDNIREQVEE-EAEGKADLQRQLSKANAEAQLWRSKYESEGVA 565
+ L R LE ++ +R Q+EE E E +A +L + Q ++++E +
Sbjct: 1566 GKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKL-RLEVNMQAMKAQFERDLQT 1624
Query: 566 RSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
R E+ EE KR L ++ E E +E ++ +K+++ +++DL+ +++
Sbjct: 1625 RDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIE 1676
Score = 68.9 bits (161), Expect = 2e-11
Identities = 52/234 (22%), Positives = 105/234 (44%), Gaps = 1/234 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDH-LSNEKAAQEKIVKQLQHQLNE 196
V +M QL++L E + + + ++A + L E+ + L Q+ E
Sbjct: 1583 VEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRE 1642
Query: 197 VQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRL 376
++++ ++ + A+KKK+ I+ DL Q+E A ++ K L Q++D +R
Sbjct: 1643 LEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRE 1702
Query: 377 ADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESE 556
+E R + + + E L ++ ++ + E A +R A E + +
Sbjct: 1703 LEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNS 1762
Query: 557 GVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEV 718
+S L+E KR+L+AR+A+ EE +E + L ++ +V+ L E+
Sbjct: 1763 ASGKSALLDE-KRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAEL 1815
Score = 60.1 bits (139), Expect = 9e-09
Identities = 52/225 (23%), Positives = 105/225 (46%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD 214
+QL + + A+ + + F+E ++RA L AA+++ ++++ H L + +
Sbjct: 925 QQLLEEKNILAEQLQAETELFAEAEEMRARL-------AAKKQELEEILHDLESRVEEEE 977
Query: 215 EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEAR 394
E N+ L + KKK+ DL QL+E E +L KV+ +++ +
Sbjct: 978 ERNQILQN---EKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLED 1034
Query: 395 ERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSE 574
+ + + + + +E + Q+ EE E +L + +K + + E R +
Sbjct: 1035 QNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTR-Q 1093
Query: 575 ELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQ 709
ELE+AKRKL + ++ I L ++ ++ K +LA + E+LQ
Sbjct: 1094 ELEKAKRKLDGETTDLQDQIAELQAQI---DELKLQLAKKEEELQ 1135
Score = 57.6 bits (133), Expect = 5e-08
Identities = 53/232 (22%), Positives = 107/232 (46%), Gaps = 3/232 (1%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD 214
E + QL KL+A+ + Y E+ + RA D + + EK +K L+ ++ ++Q +
Sbjct: 1684 EVIKQLRKLQAQMK----DYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELA 1739
Query: 215 EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEAR 394
+ R A++ E +L ++ + S S L K L ++ + +EE
Sbjct: 1740 SSER-------ARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQS 1792
Query: 395 ERATLLGKFRNLEHDLDNIREQV--EEEAEGKAD-LQRQLSKANAEAQLWRSKYESEGVA 565
L +FR +D + ++ E A K+D ++QL + N E L E EG
Sbjct: 1793 NMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKE--LKAKLQELEGAV 1850
Query: 566 RSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
+S + + L+A++ + EE +E ++ A K +R +++++ ++V+
Sbjct: 1851 KS-KFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVE 1901
Score = 54.8 bits (126), Expect = 3e-07
Identities = 47/195 (24%), Positives = 93/195 (47%), Gaps = 10/195 (5%)
Frame = +2
Query: 155 QEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLE-------EAESQ 313
QE+ ++ +L +V+ K + L +++ ++L E + L QL+ EAE
Sbjct: 892 QEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEM 951
Query: 314 VSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADL 493
++L+ K L L D + +EE L + + ++ + ++ EQ++EE EG A
Sbjct: 952 RARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEE-EG-ARQ 1009
Query: 494 QRQLSKANAEAQLWRSKYESEGVA---RSEELEEAKRKLQARLAEAEETIESLNQKVVAL 664
+ QL K AEA++ K E E + ++ + + K+ ++ R+AE + +K L
Sbjct: 1010 KLQLEKVTAEAKI--KKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNL 1067
Query: 665 EKTKQRLATEVEDLQ 709
K + + + DL+
Sbjct: 1068 AKIRNKQEVMISDLE 1082
Score = 49.6 bits (113), Expect = 1e-05
Identities = 51/238 (21%), Positives = 107/238 (44%), Gaps = 10/238 (4%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
++++ E + + KAEK + E+ L+ L+ + AAQ+++ + + ++ E+
Sbjct: 1162 IAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAEL 1221
Query: 200 QSKADEANRTLN-DLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRL 376
+ +E + + +++ + +L QLE+A+ + L K K L T D K L
Sbjct: 1222 KKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLET---DNKEL 1278
Query: 377 ADEE---ARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAE---AQLWR 538
A E + +A K + L+ + + +V E + +L + SK E
Sbjct: 1279 ACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLL 1338
Query: 539 SKYESEGVARSEELEEAKRKLQ-ARLAEAEETIESLN--QKVVALEKTKQRLATEVED 703
+ E +G+ +++ + +LQ + EET + LN ++ LE+ K L + E+
Sbjct: 1339 EEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEE 1396
Score = 47.6 bits (108), Expect = 5e-05
Identities = 51/240 (21%), Positives = 113/240 (47%), Gaps = 7/240 (2%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
V+ E+L ++ K ++ + + E+ ++ L EK + +QLQ + E+
Sbjct: 889 VTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNI---LAEQLQAE-TEL 944
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
++A+E L A K++L DL ++EE E + L K + ++D +
Sbjct: 945 FAEAEEMRARLA---AKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQL 1001
Query: 380 DEE--AR-----ERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWR 538
DEE AR E+ T K + +E ++ + +Q + + K ++ ++++ +++
Sbjct: 1002 DEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQL---- 1057
Query: 539 SKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEV 718
+E +++ L + + K + +++ EE ++ + LEK K++L E DLQ ++
Sbjct: 1058 ----AEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQI 1113
Score = 40.7 bits (91), Expect = 0.006
Identities = 25/97 (25%), Positives = 42/97 (43%)
Frame = +2
Query: 53 NKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTL 232
NKL + EK + F +V D R D + +KQL+ QL E + +A AN +
Sbjct: 1883 NKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASR 1942
Query: 233 NDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVS 343
L + N L R++ ++++ + I S
Sbjct: 1943 RKLQRELDDATEANEGLSREVSTLKNRLRRGGPISFS 1979
>M25139-1|AAA60385.1| 611|Homo sapiens myosin heavy chain
beta-subunit protein.
Length = 611
Score = 126 bits (303), Expect = 1e-28
Identities = 58/101 (57%), Positives = 77/101 (76%)
Frame = +2
Query: 422 RNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKL 601
++ HD D +REQ EEE E KA+LQR LSKAN+E WR+KYE++ + R+EELEEAK+KL
Sbjct: 10 QSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKL 69
Query: 602 QARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
RL EAEE +E++N K +LEKTK RL E+EDL ++V+R
Sbjct: 70 AQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVER 110
Score = 73.7 bits (173), Expect = 7e-13
Identities = 51/237 (21%), Positives = 109/237 (45%), Gaps = 1/237 (0%)
Frame = +2
Query: 14 RFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLN 193
R V + LD + + +A + + + ++N++ L H + A +K VK LQ L
Sbjct: 268 RVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLK 327
Query: 194 EVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKR 373
+ Q + D+A R +DL + N+ L +LEE + V Q + + +L +T
Sbjct: 328 DTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLADRELIETSE 387
Query: 374 LADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYES 553
+ +L+ + + ++ DL ++ +VEE + + + + KA +A + + +
Sbjct: 388 RVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKK 447
Query: 554 EGVARSEELEEAKRKLQARLAEAEETIESLNQ-KVVALEKTKQRLATEVEDLQLEVD 721
E S LE K+ ++ + + + ++ Q + +K Q+L V +L+ E++
Sbjct: 448 E-QDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELE 503
Score = 62.5 bits (145), Expect = 2e-09
Identities = 45/200 (22%), Positives = 92/200 (46%), Gaps = 1/200 (0%)
Frame = +2
Query: 113 LRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD-EANRTLNDLDAAKKKLSIENSDLLR 289
LR + + KA ++++ + ++ + ++K + +A + +L+ AKKKL+ +
Sbjct: 19 LREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEE 78
Query: 290 QLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEE 469
+E ++ S L K K L ++ED + A L K RN + L +++ EE
Sbjct: 79 AVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEE 138
Query: 470 EAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQ 649
Q++ + E ++ YE E + E + + LQ +++ E + S +
Sbjct: 139 SQSELESSQKEARSLSTELFKLKNAYE-ESLEHLETFKRENKNLQEEISDLTEQLGSSGK 197
Query: 650 KVVALEKTKQRLATEVEDLQ 709
+ LEK +++L E +LQ
Sbjct: 198 TIHELEKVRKQLEAEKMELQ 217
Score = 58.8 bits (136), Expect = 2e-08
Identities = 46/235 (19%), Positives = 109/235 (46%), Gaps = 1/235 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+SD+ EQL K + EK R Q +E +L++ L+ +E + + Q + N++
Sbjct: 185 ISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQI 244
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQV-SQLSKIKVSLTTQLEDTKRL 376
+++ + ++ K+ + D L+ +AE++ ++ ++K + L + +
Sbjct: 245 KAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQ 304
Query: 377 ADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESE 556
R A + ++L+ L + + Q+++ DL+ ++ L +++ E E
Sbjct: 305 LSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELE-E 363
Query: 557 GVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
A E+ E +++ L E E ++ L+ + +L K+++ ++ LQ EV+
Sbjct: 364 LRAVVEQTERSRKLADRELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVE 418
Score = 52.4 bits (120), Expect = 2e-06
Identities = 57/244 (23%), Positives = 110/244 (45%), Gaps = 19/244 (7%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQ-EKIVKQLQHQLNEVQSKA 211
EQ ++ + KA+ ++ ++ SEV R + + ++ + E+ K+L +L E +
Sbjct: 21 EQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAV 80
Query: 212 DEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADE-- 385
+ N + L+ K +L E DL+ +E + + + L K + + L + K+ +E
Sbjct: 81 EAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQ 140
Query: 386 --------EARERATLLGKFRN-----LEHDLDNIREQVEEEAEGKADLQRQLSKANA-- 520
EAR +T L K +N LEH L+ + + + E +DL QL +
Sbjct: 141 SELESSQKEARSLSTELFKLKNAYEESLEH-LETFKRENKNLQEEISDLTEQLGSSGKTI 199
Query: 521 -EAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEV 697
E + R + E+E + LEEA+ L+ + NQ +E+ +LA +
Sbjct: 200 HELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIER---KLAEKD 256
Query: 698 EDLQ 709
E+++
Sbjct: 257 EEME 260
Score = 52.0 bits (119), Expect = 2e-06
Identities = 47/217 (21%), Positives = 90/217 (41%), Gaps = 1/217 (0%)
Frame = +2
Query: 74 EKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAK 253
E+ + + V+ L+ LD + + ++ K+++ LNE++ + ANR +
Sbjct: 260 EQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQV 319
Query: 254 KKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNL- 430
K L D QL++A L K +++ + + + EE R + R L
Sbjct: 320 KSLQSLLKDTQIQLDDAVRANDDL-KENIAIVERRNNLLQAELEELRAVVEQTERSRKLA 378
Query: 431 EHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQAR 610
+ +L E+V+ L Q K +A+ +++ E E V EE +K
Sbjct: 379 DRELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVE-EAVQECRNAEEKAKKAITD 437
Query: 611 LAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
A E ++ LE+ K+ + ++DLQ +D
Sbjct: 438 AAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLD 474
Score = 51.6 bits (118), Expect = 3e-06
Identities = 48/215 (22%), Positives = 103/215 (47%), Gaps = 8/215 (3%)
Frame = +2
Query: 101 EVNDLRAGLDHLSNEKAAQ-EKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENS 277
E N ++A ++ EK + E+ + ++ +Q+ D R+ N+ KKK+ + +
Sbjct: 240 EFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLN 299
Query: 278 DLLRQLEEAESQVSQLSKIKVSLTTQLEDTK-RL-----ADEEARERATLLGKFRN-LEH 436
++ QL A ++ K SL + L+DT+ +L A+++ +E ++ + N L+
Sbjct: 300 EMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQA 359
Query: 437 DLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLA 616
+L+ +R VE+ + R+L + + QL S+ S + + ++++ +LQ +
Sbjct: 360 ELEELRAVVEQTERSRKLADRELIETSERVQLLHSQNTSL-INQKKKMDADLSQLQTEVE 418
Query: 617 EAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
EA + + +K +K A E+L+ E D
Sbjct: 419 EAVQECRNAEEKA---KKAITDAAMMAEELKKEQD 450
Score = 50.0 bits (114), Expect = 9e-06
Identities = 39/169 (23%), Positives = 80/169 (47%), Gaps = 2/169 (1%)
Frame = +2
Query: 29 MGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSN-EKAAQEKIVKQLQHQLNEVQS 205
M E+L + A E+ + + DL+ LD +K +++L+ ++ E+++
Sbjct: 441 MAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEN 500
Query: 206 KADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADE 385
+ + + + +K +L Q EE + +L + L +++ KR A+E
Sbjct: 501 ELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEE 560
Query: 386 EARERATLLGKFRNLEHDLDNIREQVEEEAEGKADL-QRQLSKANAEAQ 529
+ T L KFR ++H+LD EAE +AD+ + Q++K A+++
Sbjct: 561 AEEQANTNLSKFRKVQHELD--------EAEERADIAESQVNKLRAKSR 601
Score = 48.8 bits (111), Expect = 2e-05
Identities = 64/257 (24%), Positives = 116/257 (45%), Gaps = 24/257 (9%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDH-------LSNEKAAQEKIVKQL 178
+++M QL N++ A+A+K S + D + LD L A E+ L
Sbjct: 298 LNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLL 357
Query: 179 QHQLNEVQSKADE-------ANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLS--- 328
Q +L E+++ ++ A+R L + + L +N+ L+ Q ++ ++ +SQL
Sbjct: 358 QAELEELRAVVEQTERSRKLADRELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEV 417
Query: 329 KIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLS 508
+ V E+ + A +A A L K ++ L+ +++ +E+ + DLQ +L
Sbjct: 418 EEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIK---DLQHRLD 474
Query: 509 KANAEAQLWRSKYESEGVARSEELE---EAKRKLQAR----LAEAEETIESLNQKVVALE 667
+A A K + AR ELE EA++K A + ++E I+ L +
Sbjct: 475 EAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDR 534
Query: 668 KTKQRLATEVEDLQLEV 718
K RL V+ LQL+V
Sbjct: 535 KNLLRLQDLVDKLQLKV 551
>BC117690-1|AAI17691.1| 1976|Homo sapiens myosin, heavy chain 10,
non-muscle protein.
Length = 1976
Score = 126 bits (303), Expect = 1e-28
Identities = 78/237 (32%), Positives = 130/237 (54%), Gaps = 3/237 (1%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+ ++ EQL+Q + KA EK + ++ +L + L KA E K+L Q+ E+
Sbjct: 1205 LEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQEL 1264
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
+K E +R +L KL E ++ LEEAE + + +K SL +QL+DT+ L
Sbjct: 1265 HAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELL 1324
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEG 559
EE R++ L + R LE + ++++EQ EEE E + +L++Q+ ++ + K + +
Sbjct: 1325 QEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDD- 1383
Query: 560 VARSEELEEAKRKLQARLAEAEETIESLNQKVVA---LEKTKQRLATEVEDLQLEVD 721
+ E LEEAK+KL L +AE + L +K +A LEKTK RL E +DL +++D
Sbjct: 1384 LGTIESLEEAKKKL---LKDAEALSQRLEEKALAYDKLEKTKNRLQQEPDDLTVDLD 1437
Score = 74.5 bits (175), Expect = 4e-13
Identities = 65/243 (26%), Positives = 109/243 (44%), Gaps = 22/243 (9%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+ + E+L + + AE+ R + E+ + +G L +EK E + QL+ +L E
Sbjct: 1689 ILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEE 1748
Query: 200 QSKADEANR----------TLN-----------DLDAAKKKLSIENSDLLRQLEEAESQV 316
QS + N TLN D A+++L +N +L +L+E E V
Sbjct: 1749 QSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAV 1808
Query: 317 SQLSKIKVS-LTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADL 493
K +S L ++ + ++EA+ERA R E L I QVE+E
Sbjct: 1809 KSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQY 1868
Query: 494 QRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKT 673
+ Q+ KANA + + + E E + ++RKLQ L +A E E L+++V L+
Sbjct: 1869 KEQMEKANARMKQLKRQLE-EAEEEATRANASRRKLQRELDDATEANEGLSREVSTLKNR 1927
Query: 674 KQR 682
+R
Sbjct: 1928 LRR 1930
Score = 69.7 bits (163), Expect = 1e-11
Identities = 54/232 (23%), Positives = 105/232 (45%), Gaps = 1/232 (0%)
Frame = +2
Query: 29 MGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSK 208
+ ++L++ K EK + + E +DL LDH + EK K+ L E +S
Sbjct: 1404 LSQRLEEKALAYDKLEKTKNRLQQEPDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSI 1463
Query: 209 ADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEE 388
+ + +A ++ + L R LEEA + + L +ED D+
Sbjct: 1464 SARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDV 1523
Query: 389 ARERATLLGKFRNLEHDLDNIREQVEE-EAEGKADLQRQLSKANAEAQLWRSKYESEGVA 565
+ L R LE ++ +R Q+EE E E +A +L + Q ++++E +
Sbjct: 1524 GKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKL-RLEVNMQAMKAQFERDLQT 1582
Query: 566 RSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
R E+ EE KR L ++ E E +E ++ +K+++ +++DL+ +++
Sbjct: 1583 RDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIE 1634
Score = 69.3 bits (162), Expect = 1e-11
Identities = 55/234 (23%), Positives = 104/234 (44%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+ D E L + + K Q E N L+ + + EK V LQ QL +
Sbjct: 1317 LQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADT 1376
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
+ K D+ T+ L+ AKKKL + L ++LEE +L K K L + +D
Sbjct: 1377 KKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQEPDDLTVDL 1436
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEG 559
D + + + L K + + L + AE + + + + +A L ++ E
Sbjct: 1437 DHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKA-LSLARALEEA 1495
Query: 560 VARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
+ EE E ++L+A + + + + + + V LEK+K+ L +VE+++ +++
Sbjct: 1496 LEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLE 1549
Score = 68.9 bits (161), Expect = 2e-11
Identities = 52/234 (22%), Positives = 105/234 (44%), Gaps = 1/234 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDH-LSNEKAAQEKIVKQLQHQLNE 196
V +M QL++L E + + + ++A + L E+ + L Q+ E
Sbjct: 1541 VEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRE 1600
Query: 197 VQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRL 376
++++ ++ + A+KKK+ I+ DL Q+E A ++ K L Q++D +R
Sbjct: 1601 LEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRE 1660
Query: 377 ADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESE 556
+E R + + + E L ++ ++ + E A +R A E + +
Sbjct: 1661 LEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNS 1720
Query: 557 GVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEV 718
+S L+E KR+L+AR+A+ EE +E + L ++ +V+ L E+
Sbjct: 1721 ASGKSALLDE-KRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAEL 1773
Score = 60.1 bits (139), Expect = 9e-09
Identities = 52/225 (23%), Positives = 105/225 (46%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD 214
+QL + + A+ + + F+E ++RA L AA+++ ++++ H L + +
Sbjct: 883 QQLLEEKNILAEQLQAETELFAEAEEMRARL-------AAKKQELEEILHDLESRVEEEE 935
Query: 215 EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEAR 394
E N+ L + KKK+ DL QL+E E +L KV+ +++ +
Sbjct: 936 ERNQILQN---EKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLED 992
Query: 395 ERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSE 574
+ + + + + +E + Q+ EE E +L + +K + + E R +
Sbjct: 993 QNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTR-Q 1051
Query: 575 ELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQ 709
ELE+AKRKL + ++ I L ++ ++ K +LA + E+LQ
Sbjct: 1052 ELEKAKRKLDGETTDLQDQIAELQAQI---DELKLQLAKKEEELQ 1093
Score = 57.6 bits (133), Expect = 5e-08
Identities = 53/232 (22%), Positives = 107/232 (46%), Gaps = 3/232 (1%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD 214
E + QL KL+A+ + Y E+ + RA D + + EK +K L+ ++ ++Q +
Sbjct: 1642 EVIKQLRKLQAQMK----DYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELA 1697
Query: 215 EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEAR 394
+ R A++ E +L ++ + S S L K L ++ + +EE
Sbjct: 1698 SSER-------ARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQS 1750
Query: 395 ERATLLGKFRNLEHDLDNIREQV--EEEAEGKAD-LQRQLSKANAEAQLWRSKYESEGVA 565
L +FR +D + ++ E A K+D ++QL + N E L E EG
Sbjct: 1751 NMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKE--LKAKLQELEGAV 1808
Query: 566 RSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
+S + + L+A++ + EE +E ++ A K +R +++++ ++V+
Sbjct: 1809 KS-KFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVE 1859
Score = 54.8 bits (126), Expect = 3e-07
Identities = 47/195 (24%), Positives = 93/195 (47%), Gaps = 10/195 (5%)
Frame = +2
Query: 155 QEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLE-------EAESQ 313
QE+ ++ +L +V+ K + L +++ ++L E + L QL+ EAE
Sbjct: 850 QEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEM 909
Query: 314 VSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADL 493
++L+ K L L D + +EE L + + ++ + ++ EQ++EE EG A
Sbjct: 910 RARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEE-EG-ARQ 967
Query: 494 QRQLSKANAEAQLWRSKYESEGVA---RSEELEEAKRKLQARLAEAEETIESLNQKVVAL 664
+ QL K AEA++ K E E + ++ + + K+ ++ R+AE + +K L
Sbjct: 968 KLQLEKVTAEAKI--KKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNL 1025
Query: 665 EKTKQRLATEVEDLQ 709
K + + + DL+
Sbjct: 1026 AKIRNKQEVMISDLE 1040
Score = 49.6 bits (113), Expect = 1e-05
Identities = 51/238 (21%), Positives = 107/238 (44%), Gaps = 10/238 (4%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
++++ E + + KAEK + E+ L+ L+ + AAQ+++ + + ++ E+
Sbjct: 1120 IAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAEL 1179
Query: 200 QSKADEANRTLN-DLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRL 376
+ +E + + +++ + +L QLE+A+ + L K K L T D K L
Sbjct: 1180 KKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLET---DNKEL 1236
Query: 377 ADEE---ARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAE---AQLWR 538
A E + +A K + L+ + + +V E + +L + SK E
Sbjct: 1237 ACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLL 1296
Query: 539 SKYESEGVARSEELEEAKRKLQ-ARLAEAEETIESLN--QKVVALEKTKQRLATEVED 703
+ E +G+ +++ + +LQ + EET + LN ++ LE+ K L + E+
Sbjct: 1297 EEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEE 1354
Score = 47.6 bits (108), Expect = 5e-05
Identities = 51/240 (21%), Positives = 113/240 (47%), Gaps = 7/240 (2%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
V+ E+L ++ K ++ + + E+ ++ L EK + +QLQ + E+
Sbjct: 847 VTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNI---LAEQLQAE-TEL 902
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
++A+E L A K++L DL ++EE E + L K + ++D +
Sbjct: 903 FAEAEEMRARLA---AKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQL 959
Query: 380 DEE--AR-----ERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWR 538
DEE AR E+ T K + +E ++ + +Q + + K ++ ++++ +++
Sbjct: 960 DEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQL---- 1015
Query: 539 SKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEV 718
+E +++ L + + K + +++ EE ++ + LEK K++L E DLQ ++
Sbjct: 1016 ----AEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQI 1071
Score = 40.7 bits (91), Expect = 0.006
Identities = 25/97 (25%), Positives = 42/97 (43%)
Frame = +2
Query: 53 NKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTL 232
NKL + EK + F +V D R D + +KQL+ QL E + +A AN +
Sbjct: 1841 NKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASR 1900
Query: 233 NDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVS 343
L + N L R++ ++++ + I S
Sbjct: 1901 RKLQRELDDATEANEGLSREVSTLKNRLRRGGPISFS 1937
>M31013-1|AAA36349.1| 1247|Homo sapiens protein ( Human nonmuscle
myosin heavy chain (NMHC) mRNA, 3' end. ).
Length = 1247
Score = 121 bits (291), Expect = 3e-27
Identities = 77/235 (32%), Positives = 129/235 (54%), Gaps = 1/235 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
V ++ EQL+Q ++KA EK + +E +L + L E K+++ QL E+
Sbjct: 484 VEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGGRDSEHKRKKVEAQLQEL 543
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
Q K +E R +L KL +E ++ L +++S+ S+L+K +L +QL+DT+ L
Sbjct: 544 QVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELL 603
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQV-EEEAEGKADLQRQLSKANAEAQLWRSKYESE 556
EE R++ +L K + +E + ++ REQ+ EEE E K +L++Q++ +A+ + K E +
Sbjct: 604 QEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEEAKHNLEKQIATLHAQVADMKKKME-D 662
Query: 557 GVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
V E EE KRKLQ L + E LEKTK RL E++DL +++D
Sbjct: 663 SVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLD 717
Score = 77.0 bits (181), Expect = 7e-14
Identities = 53/219 (24%), Positives = 104/219 (47%), Gaps = 1/219 (0%)
Frame = +2
Query: 68 KAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDA 247
K EK + + E++DL LDH EK K+ L E ++ + + + +A
Sbjct: 697 KLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEA 756
Query: 248 AKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRN 427
++ + L R LEEA Q ++L ++ T++ED D+ + L R
Sbjct: 757 EAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRA 816
Query: 428 LEHDLDNIREQVEE-EAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQ 604
LE ++ ++ Q+EE E E +A +L + Q ++++E + R E+ EE K++L
Sbjct: 817 LEQQVEEMKTQLEELEDELQATEDAKL-RLEVNLQAMKAQFERDLQGRDEQSEEKKKQLV 875
Query: 605 ARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
++ E E +E ++ +++L +++DL+ +D
Sbjct: 876 RQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHID 914
Score = 66.1 bits (154), Expect = 1e-10
Identities = 49/235 (20%), Positives = 105/235 (44%), Gaps = 1/235 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDH-LSNEKAAQEKIVKQLQHQLNE 196
V +M QL++L E + + + ++A + L E+ KQL Q+ E
Sbjct: 821 VEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVRE 880
Query: 197 VQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRL 376
++++ ++ + + AA+KKL ++ DL ++ A + K L Q++D R
Sbjct: 881 MEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRE 940
Query: 377 ADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESE 556
D+ R +L + + E L ++ ++ + E A +R +A E + +
Sbjct: 941 LDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANS 1000
Query: 557 GVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
+ LEE KR+L+AR+A+ EE +E + ++ +++ + +++
Sbjct: 1001 SGKGALALEE-KRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINADLN 1054
Score = 64.5 bits (150), Expect = 4e-10
Identities = 59/239 (24%), Positives = 117/239 (48%), Gaps = 12/239 (5%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD 214
EQL +L A+AE+ RA+ ++ +L L +E+ + LQ + ++Q
Sbjct: 173 EQLQAETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERYQHLQAEKKKMQQNIQ 232
Query: 215 EANRTLNDLDAAKKKLSIENSDL---LRQLEEA----ESQVSQLSKIKVSLTTQL-EDTK 370
E L + ++A++KL +E L++LEE E Q +L+K K L ++ E T
Sbjct: 233 ELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTT 292
Query: 371 RLADEEARERATLLGKFRNL-EHDLDNIREQVEEEAEGKADLQ---RQLSKANAEAQLWR 538
L +EE E++ L K +N E + ++ E++ E + + +L+ R+L + +
Sbjct: 293 NLTEEE--EKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQI 350
Query: 539 SKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLE 715
++ +++ +L + + +LQA LA EE N + + + + +++ EDL+ E
Sbjct: 351 AELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESE 409
Score = 62.9 bits (146), Expect = 1e-09
Identities = 56/241 (23%), Positives = 107/241 (44%), Gaps = 7/241 (2%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNE-KAAQEKIVKQLQHQLNE 196
+ D E L + N+ K Q E N R L+ E K EK + L Q+ +
Sbjct: 596 LQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEEAKHNLEKQIATLHAQVAD 655
Query: 197 VQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRL 376
++ K +++ L + K+KL + L ++ EE + +L K K L +L+D L
Sbjct: 656 MKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDL--L 713
Query: 377 ADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYES- 553
D + + ++ NLE + + EE A + +A AEA+ +K S
Sbjct: 714 VDLDHQRQSAC-----NLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSL 768
Query: 554 -----EGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEV 718
E + + ELE ++ + + + + + + + V LEK+K+ L +VE+++ ++
Sbjct: 769 ARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQL 828
Query: 719 D 721
+
Sbjct: 829 E 829
Score = 62.9 bits (146), Expect = 1e-09
Identities = 59/243 (24%), Positives = 114/243 (46%), Gaps = 13/243 (5%)
Frame = +2
Query: 14 RFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLN 193
R V +M +L+ K ++ A R + ++ DL A +D + + K +++LQ Q+
Sbjct: 876 RQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMK 935
Query: 194 EVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQ-LSKIKVSLTTQLEDTK 370
+ + D+ + ++ A K EN L+ +E Q+ + L+ + + ++
Sbjct: 936 DCMRELDDTRASREEILAQAK----ENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERD 991
Query: 371 RLADEEARER---ATLLGKFRNLEHDLDNIREQVEEEAEGKADL--------QRQLSKAN 517
LADE A A L + R LE + + E++EEE +G +L Q+ + N
Sbjct: 992 ELADEIANSSGKGALALEEKRRLEARIAQLEEELEEE-QGNTELINDRLKKANLQIDQIN 1050
Query: 518 AEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIES-LNQKVVALEKTKQRLATE 694
A+ L R + AR ++LE ++L+ +L E E T++S + ALE +L +
Sbjct: 1051 ADLNLERGHAQKNENAR-QQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQ 1109
Query: 695 VED 703
+++
Sbjct: 1110 LDN 1112
Score = 58.8 bits (136), Expect = 2e-08
Identities = 50/200 (25%), Positives = 91/200 (45%), Gaps = 10/200 (5%)
Frame = +2
Query: 155 QEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLE-------EAESQ 313
QE+ + + +L +V+ K A L +++ + +L E L QL+ EAE
Sbjct: 129 QEEEMMAKEEELVKVREKQLAAENRLMEMETLQSQLMAEKLQLQEQLQAETELCAEAEEL 188
Query: 314 VSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADL 493
++L+ K L D + +EE L + + ++ ++ + EQ+EEE + L
Sbjct: 189 RARLTAKKQELEEICHDLEARVEEEEERYQHLQAEKKKMQQNIQELEEQLEEEESARQKL 248
Query: 494 QRQLSKANAEAQLWRSKYESEGVARSEE---LEEAKRKLQARLAEAEETIESLNQKVVAL 664
QL K EA+L K E E + ++ L + K+ L+ R+AE + +K +L
Sbjct: 249 --QLEKVTTEAKL--KKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSL 304
Query: 665 EKTKQRLATEVEDLQLEVDR 724
K K + + DL+ + R
Sbjct: 305 AKLKNKHEAMITDLEERLRR 324
Score = 57.6 bits (133), Expect = 5e-08
Identities = 67/256 (26%), Positives = 113/256 (44%), Gaps = 28/256 (10%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD 214
+Q +L K K E A++ + + + L+ K E ++ L+ +L + +
Sbjct: 271 DQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQ 330
Query: 215 EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEAR 394
E +T ++KL +++DL Q+ E ++Q+++L +L+ +EEA
Sbjct: 331 ELEKT-------RRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAA 383
Query: 395 ERATLLGKFRNLEHDLDNIREQVEEE--AEGKADLQ-RQLSK--------------ANAE 523
++ L K R LE + ++E +E E + KA+ Q R L + + A
Sbjct: 384 QKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAA 443
Query: 524 AQLWRSKYESEGVARSEELEEAKRKLQARLAE--------AEETIESLNQ--KVVA-LEK 670
Q RSK E E + LEE + +A++ E EE E L Q +V A LEK
Sbjct: 444 QQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEK 503
Query: 671 TKQRLATEVEDLQLEV 718
KQ L E +L EV
Sbjct: 504 AKQTLENERGELANEV 519
Score = 53.6 bits (123), Expect = 8e-07
Identities = 50/228 (21%), Positives = 110/228 (48%), Gaps = 8/228 (3%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+S++ E L+ + KAEK + E+ L+ L+ + AAQ+++ + + ++N +
Sbjct: 399 ISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNIL 458
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
+ +E +T +A +++ ++S + +L E Q+ Q ++K +L + +
Sbjct: 459 KKTLEEEAKT---HEAQIQEMRQKHSQAVEELAE---QLEQTKRVKANLEKAKQTLENER 512
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEE------EAEG-KADLQRQLSKANAEAQLWR 538
E A E LL R+ EH + Q++E E E + +L +++K E
Sbjct: 513 GELANEVKVLLQGGRDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVT 572
Query: 539 SKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALE-KTKQ 679
S+ ++S +L + L+++L + +E ++ N++ ++L K KQ
Sbjct: 573 GLL-SQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQ 619
Score = 53.2 bits (122), Expect = 1e-06
Identities = 34/122 (27%), Positives = 57/122 (46%)
Frame = +2
Query: 59 LKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLND 238
+K+K + +++ L LD+ + E+ A K V++ + +L +V + D+ R
Sbjct: 1088 VKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQ 1147
Query: 239 LDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGK 418
K S L RQLEEAE + + + + L +LED AD RE ++L K
Sbjct: 1148 YKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKNK 1207
Query: 419 FR 424
R
Sbjct: 1208 LR 1209
Score = 51.2 bits (117), Expect = 4e-06
Identities = 48/230 (20%), Positives = 91/230 (39%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+ ++ EQL++ + K + + +++ L L ++ K K L+ ++ E
Sbjct: 231 IQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEF 290
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
+ E L K K +DL +L E Q +L K + L D
Sbjct: 291 TTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQI 350
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEG 559
E + A L + E +L +VEEEA K +++ + ++ + ESE
Sbjct: 351 AELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESER 410
Query: 560 VARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQ 709
+R+ + E+ KR L L + +E A ++ + + EV L+
Sbjct: 411 ASRN-KAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILK 459
Score = 49.6 bits (113), Expect = 1e-05
Identities = 56/238 (23%), Positives = 102/238 (42%), Gaps = 22/238 (9%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD 214
++ D+L A + A E L A + L E ++ + + +L + + D
Sbjct: 988 QERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQID 1047
Query: 215 EANRTLN-------DLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVS-LTTQLEDTK 370
+ N LN + A+++L +N +L +L+E E V K ++ L ++ +
Sbjct: 1048 QINADLNLERGHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLE 1107
Query: 371 RLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEG------KAD--------LQRQLS 508
D E +ER + R E L ++ QV++E +AD L+RQL
Sbjct: 1108 EQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLE 1167
Query: 509 KANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQR 682
+A EAQ ++RKLQ L +A ET +++N++V +L+ +R
Sbjct: 1168 EAEEEAQ---------------RANASRRKLQRELEDATETADAMNREVSSLKNKLRR 1210
>AY165122-1|AAO39147.1| 1995|Homo sapiens myosin heavy chain protein.
Length = 1995
Score = 120 bits (290), Expect = 4e-27
Identities = 78/239 (32%), Positives = 127/239 (53%), Gaps = 1/239 (0%)
Frame = +2
Query: 11 GRFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQL 190
G+ + ++ EQL+Q + K EK R +EV++LRA L L + E+ ++L+ QL
Sbjct: 1219 GQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQL 1278
Query: 191 NEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTK 370
EVQ +A + R + ++ E ++ L EAES+ +LSK S QL D +
Sbjct: 1279 QEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQ 1338
Query: 371 RLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYE 550
L EE R + L + R +E + +REQ+EEEA + R+L A A+ WR + E
Sbjct: 1339 ELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQE 1398
Query: 551 SEGVARSEELEEAKRKLQARLAEA-EETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
E A E EEA+R+ AR AEA + + + V LE+ ++RL E++D +++++
Sbjct: 1399 EEAGA-LEAGEEARRR-AAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQ 1455
Score = 66.5 bits (155), Expect = 1e-10
Identities = 47/228 (20%), Positives = 105/228 (46%), Gaps = 2/228 (0%)
Frame = +2
Query: 41 LDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEA 220
L++ + + + E+ +E+ L + D + E+ + + N+++++ E
Sbjct: 1509 LEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTEL 1568
Query: 221 NRTLNDLDAAKKKLSIENSDLLRQLE-EAESQVSQLSKIKVSLTTQLEDTKRLADEEARE 397
L + AK +L + L Q E + + + + + L QL D + DEE ++
Sbjct: 1569 EDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQ 1628
Query: 398 RATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAE-AQLWRSKYESEGVARSE 574
R + + LE +L+ ++ Q+ +GK + +QL K A+ +LWR E+ E
Sbjct: 1629 RTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETR--TSRE 1686
Query: 575 ELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEV 718
E+ R+ + RL E + L +++ A ++ +++ + +++ EV
Sbjct: 1687 EIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEV 1734
Score = 62.1 bits (144), Expect = 2e-09
Identities = 55/232 (23%), Positives = 101/232 (43%), Gaps = 2/232 (0%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD 214
EQL++ + +A + +++++ R + + A E+ ++ + + +
Sbjct: 1367 EQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLA 1426
Query: 215 EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKR--LADEE 388
E T++ L+ +++L E D LE+ VS L K + L + K L E
Sbjct: 1427 EKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVE 1486
Query: 389 ARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVAR 568
RERA G+ R E ++ +EEE E + +L+RQ AE + S + G +
Sbjct: 1487 ERERAEAEGRER--EARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKS- 1543
Query: 569 SEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
ELE A R + + + L ++ A E K RL V+ L+ + +R
Sbjct: 1544 VHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHER 1595
Score = 60.5 bits (140), Expect = 7e-09
Identities = 55/224 (24%), Positives = 105/224 (46%), Gaps = 5/224 (2%)
Frame = +2
Query: 26 DMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQS 205
+M +++ N KA + + Q + L + L E++ E + + + L +V+S
Sbjct: 1729 EMADEVANGNLSKAAILEEKRQLEGRLGQLE---EELEEEQSNSELLNDRYRKLLLQVES 1785
Query: 206 KADE--ANRTLN-DLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVS-LTTQLEDTKR 373
E A R+ + ++ +++L + +L +L E ++ K+ ++ L ++L +
Sbjct: 1786 LTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEE 1845
Query: 374 LADEEARERATLLGKF-RNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYE 550
++E RER L GK R E L + QVEEE L+ QL K N + + + E
Sbjct: 1846 QLEQETRERI-LSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLE 1904
Query: 551 SEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQR 682
E + + +R+LQ L + E+ ES+N++V L +R
Sbjct: 1905 -EAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRR 1947
Score = 48.8 bits (111), Expect = 2e-05
Identities = 35/128 (27%), Positives = 59/128 (46%)
Frame = +2
Query: 311 QVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKAD 490
QV++ ++ + +L+ + L + ARE L G+ LE + + EQ+ EAE A+
Sbjct: 863 QVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAE 922
Query: 491 LQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEK 670
+ + A Q SE AR E EE R++Q ++ I+ L + A E
Sbjct: 923 AEETRGRLAARKQ-ELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEG 981
Query: 671 TKQRLATE 694
+Q+L E
Sbjct: 982 ARQKLQLE 989
Score = 47.2 bits (107), Expect = 7e-05
Identities = 41/195 (21%), Positives = 80/195 (41%), Gaps = 4/195 (2%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGL-DHLSNEKAAQEKIVKQLQHQLNE 196
V + +L AKAE R Q ++ +LR L + + +A + + L+ +L +
Sbjct: 1783 VESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQ 1842
Query: 197 VQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRL 376
+ + ++ R ++ +++ Q+EE QL +++ KR
Sbjct: 1843 AEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQ 1902
Query: 377 ADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKA--NAEAQLWRSKYE 550
+E E + R L+ +L+++ E E L+ +L + + R +
Sbjct: 1903 LEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFR 1962
Query: 551 -SEGVARSEELEEAK 592
EGVA EE EEA+
Sbjct: 1963 LEEGVASDEEAEEAQ 1977
Score = 45.2 bits (102), Expect = 3e-04
Identities = 36/149 (24%), Positives = 71/149 (47%), Gaps = 3/149 (2%)
Frame = +2
Query: 278 DLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIRE 457
D LR+ E+ ++ +L + +++L++ + A E LG+ E +L
Sbjct: 1058 DRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGR---KEEELQAALA 1114
Query: 458 QVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAK---RKLQARLAEAEE 628
+ E+E +A L + L +A A + ESE VAR++ ++ + +L+A E E+
Sbjct: 1115 RAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELED 1174
Query: 629 TIESLNQKVVALEKTKQRLATEVEDLQLE 715
T++S N + K +Q + + L+ E
Sbjct: 1175 TLDSTNAQQELRSKREQEVTELKKTLEEE 1203
>AB111886-1|BAC98374.1| 1571|Homo sapiens KIAA2034 protein protein.
Length = 1571
Score = 120 bits (290), Expect = 4e-27
Identities = 78/239 (32%), Positives = 127/239 (53%), Gaps = 1/239 (0%)
Frame = +2
Query: 11 GRFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQL 190
G+ + ++ EQL+Q + K EK R +EV++LRA L L + E+ ++L+ QL
Sbjct: 795 GQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQL 854
Query: 191 NEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTK 370
EVQ +A + R + ++ E ++ L EAES+ +LSK S QL D +
Sbjct: 855 QEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQ 914
Query: 371 RLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYE 550
L EE R + L + R +E + +REQ+EEEA + R+L A A+ WR + E
Sbjct: 915 ELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQE 974
Query: 551 SEGVARSEELEEAKRKLQARLAEA-EETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
E A E EEA+R+ AR AEA + + + V LE+ ++RL E++D +++++
Sbjct: 975 EEAGA-LEAGEEARRR-AAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQ 1031
Score = 68.1 bits (159), Expect = 3e-11
Identities = 61/240 (25%), Positives = 113/240 (47%), Gaps = 11/240 (4%)
Frame = +2
Query: 29 MGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSK 208
+ EQL +L A+AE+ R + + +L + L +E+ +Q+Q + +Q
Sbjct: 485 LAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQH 544
Query: 209 ADEANRTLNDLDAAKKKLSIENSDL---LRQLEE----AESQVSQLSKIKVSLTTQLEDT 367
E L + A++KL +E +++ EE E Q S+LSK + L +L +
Sbjct: 545 IQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEF 604
Query: 368 KRLADEEARERATLLGKFR-NLEHDLDNIREQVEEEAEGKADLQ---RQLSKANAEAQLW 535
A EE E+ L K R E + ++ +++ +E +G+ +L+ R+L ++E Q
Sbjct: 605 SSQAAEE-EEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQ 663
Query: 536 RSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLE 715
+ + +L + +LQA LA AE+ + Q + +L + + LA EDL+ E
Sbjct: 664 MVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESE 723
Score = 66.5 bits (155), Expect = 1e-10
Identities = 47/228 (20%), Positives = 105/228 (46%), Gaps = 2/228 (0%)
Frame = +2
Query: 41 LDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEA 220
L++ + + + E+ +E+ L + D + E+ + + N+++++ E
Sbjct: 1085 LEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTEL 1144
Query: 221 NRTLNDLDAAKKKLSIENSDLLRQLE-EAESQVSQLSKIKVSLTTQLEDTKRLADEEARE 397
L + AK +L + L Q E + + + + + L QL D + DEE ++
Sbjct: 1145 EDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQ 1204
Query: 398 RATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAE-AQLWRSKYESEGVARSE 574
R + + LE +L+ ++ Q+ +GK + +QL K A+ +LWR E+ E
Sbjct: 1205 RTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETR--TSRE 1262
Query: 575 ELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEV 718
E+ R+ + RL E + L +++ A ++ +++ + +++ EV
Sbjct: 1263 EIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEV 1310
Score = 62.1 bits (144), Expect = 2e-09
Identities = 55/232 (23%), Positives = 101/232 (43%), Gaps = 2/232 (0%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD 214
EQL++ + +A + +++++ R + + A E+ ++ + + +
Sbjct: 943 EQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLA 1002
Query: 215 EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKR--LADEE 388
E T++ L+ +++L E D LE+ VS L K + L + K L E
Sbjct: 1003 EKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVE 1062
Query: 389 ARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVAR 568
RERA G+ R E ++ +EEE E + +L+RQ AE + S + G +
Sbjct: 1063 ERERAEAEGRER--EARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKS- 1119
Query: 569 SEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
ELE A R + + + L ++ A E K RL V+ L+ + +R
Sbjct: 1120 VHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHER 1171
Score = 60.5 bits (140), Expect = 7e-09
Identities = 55/224 (24%), Positives = 105/224 (46%), Gaps = 5/224 (2%)
Frame = +2
Query: 26 DMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQS 205
+M +++ N KA + + Q + L + L E++ E + + + L +V+S
Sbjct: 1305 EMADEVANGNLSKAAILEEKRQLEGRLGQLE---EELEEEQSNSELLNDRYRKLLLQVES 1361
Query: 206 KADE--ANRTLN-DLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVS-LTTQLEDTKR 373
E A R+ + ++ +++L + +L +L E ++ K+ ++ L ++L +
Sbjct: 1362 LTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEE 1421
Query: 374 LADEEARERATLLGKF-RNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYE 550
++E RER L GK R E L + QVEEE L+ QL K N + + + E
Sbjct: 1422 QLEQETRERI-LSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLE 1480
Query: 551 SEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQR 682
E + + +R+LQ L + E+ ES+N++V L +R
Sbjct: 1481 -EAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRR 1523
Score = 60.1 bits (139), Expect = 9e-09
Identities = 47/195 (24%), Positives = 90/195 (46%), Gaps = 3/195 (1%)
Frame = +2
Query: 140 NEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVS 319
N K ++E+ K L+ +L E S+A E + L+ + K +D+ +L + E
Sbjct: 587 NSKLSKER--KLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQ 644
Query: 320 QLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQR 499
+L K+K L + + + E+ + L + E +L + E+E +A L +
Sbjct: 645 ELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLK 704
Query: 500 QLSKANAEAQLWRSKYESEGVARSEELEEAK---RKLQARLAEAEETIESLNQKVVALEK 670
L +A A + ESE VAR++ ++ + +L+A E E+T++S N + K
Sbjct: 705 SLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSK 764
Query: 671 TKQRLATEVEDLQLE 715
+Q + + L+ E
Sbjct: 765 REQEVTELKKTLEEE 779
Score = 48.8 bits (111), Expect = 2e-05
Identities = 35/128 (27%), Positives = 59/128 (46%)
Frame = +2
Query: 311 QVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKAD 490
QV++ ++ + +L+ + L + ARE L G+ LE + + EQ+ EAE A+
Sbjct: 439 QVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAE 498
Query: 491 LQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEK 670
+ + A Q SE AR E EE R++Q ++ I+ L + A E
Sbjct: 499 AEETRGRLAARKQ-ELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEG 557
Query: 671 TKQRLATE 694
+Q+L E
Sbjct: 558 ARQKLQLE 565
Score = 47.2 bits (107), Expect = 7e-05
Identities = 41/195 (21%), Positives = 80/195 (41%), Gaps = 4/195 (2%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGL-DHLSNEKAAQEKIVKQLQHQLNE 196
V + +L AKAE R Q ++ +LR L + + +A + + L+ +L +
Sbjct: 1359 VESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQ 1418
Query: 197 VQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRL 376
+ + ++ R ++ +++ Q+EE QL +++ KR
Sbjct: 1419 AEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQ 1478
Query: 377 ADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKA--NAEAQLWRSKYE 550
+E E + R L+ +L+++ E E L+ +L + + R +
Sbjct: 1479 LEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFR 1538
Query: 551 -SEGVARSEELEEAK 592
EGVA EE EEA+
Sbjct: 1539 LEEGVASDEEAEEAQ 1553
>BC049849-1|AAH49849.1| 1374|Homo sapiens MYH9 protein protein.
Length = 1374
Score = 98.7 bits (235), Expect = 2e-20
Identities = 55/175 (31%), Positives = 100/175 (57%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
V ++ EQL+Q ++KA EK + +E +L + L K E K+++ QL E+
Sbjct: 1198 VEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQEL 1257
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
Q K +E R +L KL +E ++ L +++S+ S+L+K +L +QL+DT+ L
Sbjct: 1258 QVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELL 1317
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSK 544
EE R++ +L K + +E + ++ REQ+EEE E K +L++Q++ +A+ + K
Sbjct: 1318 QEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKK 1372
Score = 64.5 bits (150), Expect = 4e-10
Identities = 59/239 (24%), Positives = 117/239 (48%), Gaps = 12/239 (5%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD 214
EQL +L A+AE+ RA+ ++ +L L +E+ + LQ + ++Q
Sbjct: 887 EQLQAETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQ 946
Query: 215 EANRTLNDLDAAKKKLSIENSDL---LRQLEEA----ESQVSQLSKIKVSLTTQL-EDTK 370
E L + ++A++KL +E L++LEE E Q +L+K K L ++ E T
Sbjct: 947 ELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTT 1006
Query: 371 RLADEEARERATLLGKFRNL-EHDLDNIREQVEEEAEGKADLQ---RQLSKANAEAQLWR 538
L +EE E++ L K +N E + ++ E++ E + + +L+ R+L + +
Sbjct: 1007 NLTEEE--EKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQI 1064
Query: 539 SKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLE 715
++ +++ +L + + +LQA LA EE N + + + + +++ EDL+ E
Sbjct: 1065 AELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESE 1123
Score = 59.7 bits (138), Expect = 1e-08
Identities = 47/200 (23%), Positives = 93/200 (46%), Gaps = 10/200 (5%)
Frame = +2
Query: 155 QEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKI 334
QE+ + + +L +V+ K A L +++ + +L E L QL+ ++ ++
Sbjct: 843 QEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEEL 902
Query: 335 KVSLTTQLEDTKRLAD------EEARERAT-LLGKFRNLEHDLDNIREQVEEEAEGKADL 493
+ LT + ++ + + EE ER L + + ++ ++ + EQ+EEE + L
Sbjct: 903 RARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKL 962
Query: 494 QRQLSKANAEAQLWRSKYESEGVARSEE---LEEAKRKLQARLAEAEETIESLNQKVVAL 664
QL K EA+L K E E + ++ L + K+ L+ R+AE + +K +L
Sbjct: 963 --QLEKVTTEAKL--KKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSL 1018
Query: 665 EKTKQRLATEVEDLQLEVDR 724
K K + + DL+ + R
Sbjct: 1019 AKLKNKHEAMITDLEERLRR 1038
Score = 59.7 bits (138), Expect = 1e-08
Identities = 52/221 (23%), Positives = 108/221 (48%), Gaps = 5/221 (2%)
Frame = +2
Query: 62 KAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDL 241
K A K + S++++L+ + L +E+A++ K KQ + E+++ E TL D
Sbjct: 1099 KNMALKKIRELESQISELQ---EDLESERASRNKAEKQKRDLGEELEALKTELEDTL-DS 1154
Query: 242 DAAKKKLSIENS---DLLRQL--EEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERAT 406
AA+++L + ++L++ EEA++ +Q+ +++ + +E+ ++ R +A
Sbjct: 1155 TAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKAN 1214
Query: 407 LLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEE 586
L + LE++ + +V+ +GK D + + K A+ Q + K+ +EG EL +
Sbjct: 1215 LEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKF-NEGERVRTELAD 1273
Query: 587 AKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQ 709
KLQ L + + K L K L ++++D Q
Sbjct: 1274 KVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQ 1314
Score = 54.0 bits (124), Expect = 6e-07
Identities = 44/222 (19%), Positives = 103/222 (46%), Gaps = 2/222 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+S++ E L+ + KAEK + E+ L+ L+ + AAQ+++ + + ++N +
Sbjct: 1113 ISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNIL 1172
Query: 200 QSKADEANRTLN-DLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRL 376
+ +E +T + ++K S +L QLE+ + + L K K +L + +
Sbjct: 1173 KKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANE 1232
Query: 377 ADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESE 556
+ + K + +E L ++ + E + +L +++K E S+
Sbjct: 1233 VKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLL-SQ 1291
Query: 557 GVARSEELEEAKRKLQARLAEAEETIESLNQKVVALE-KTKQ 679
++S +L + L+++L + +E ++ N++ ++L K KQ
Sbjct: 1292 SDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQ 1333
Score = 51.2 bits (117), Expect = 4e-06
Identities = 48/230 (20%), Positives = 91/230 (39%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+ ++ EQL++ + K + + +++ L L ++ K K L+ ++ E
Sbjct: 945 IQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEF 1004
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
+ E L K K +DL +L E Q +L K + L D
Sbjct: 1005 TTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQI 1064
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEG 559
E + A L + E +L +VEEEA K +++ + ++ + ESE
Sbjct: 1065 AELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESER 1124
Query: 560 VARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQ 709
+R+ + E+ KR L L + +E A ++ + + EV L+
Sbjct: 1125 ASRN-KAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILK 1173
>BC022376-1|AAH22376.1| 627|Homo sapiens Unknown (protein for
IMAGE:4338358) protein.
Length = 627
Score = 94.3 bits (224), Expect = 4e-19
Identities = 43/78 (55%), Positives = 59/78 (75%)
Frame = +2
Query: 491 LQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEK 670
L + KAN+E WR+KYE++ + R+EELEEAK+KL RL +AEE +E++N K +LEK
Sbjct: 450 LDTKQPKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEK 509
Query: 671 TKQRLATEVEDLQLEVDR 724
TKQRL EVEDL ++V+R
Sbjct: 510 TKQRLQNEVEDLMIDVER 527
Score = 48.0 bits (109), Expect = 4e-05
Identities = 41/160 (25%), Positives = 75/160 (46%), Gaps = 1/160 (0%)
Frame = +2
Query: 206 KADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADE 385
+ D RT +L+ AKKKL+ D +E ++ + L K K L ++ED +
Sbjct: 469 ETDAIQRT-EELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVER 527
Query: 386 EARERATLLGKFRNLEHDLDNIREQVEE-EAEGKADLQRQLSKANAEAQLWRSKYESEGV 562
A L K RN + L +++ EE AE +A Q++ + E ++ YE E +
Sbjct: 528 TNAACAALDKKQRNFDKILAEWKQKCEETHAELEAS-QKESRSLSTELFKIKNAYE-ESL 585
Query: 563 ARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQR 682
+ E L+ + LQ +++ E I +++ +K K++
Sbjct: 586 DQLETLKRENKNLQQEISDLTEQIAEGGKRIHKKKKKKKK 625
Score = 46.8 bits (106), Expect = 9e-05
Identities = 26/132 (19%), Positives = 65/132 (49%)
Frame = +2
Query: 74 EKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAK 253
E+ + + + D ++ ++ + A+ EK ++LQ+++ ++ + N LD +
Sbjct: 480 EEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQ 539
Query: 254 KKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLE 433
+ ++ ++ EE +++ K SL+T+L K +E + TL + +NL+
Sbjct: 540 RNFDKILAEWKQKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQ 599
Query: 434 HDLDNIREQVEE 469
++ ++ EQ+ E
Sbjct: 600 QEISDLTEQIAE 611
>BC004396-1|AAH04396.1| 182|Homo sapiens MYH14 protein protein.
Length = 182
Score = 81.4 bits (192), Expect = 3e-15
Identities = 54/144 (37%), Positives = 77/144 (53%), Gaps = 1/144 (0%)
Frame = +2
Query: 293 LEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEE 472
L EAES+ +LSK S QL D + L EE R + L + R +E + +REQ+EEE
Sbjct: 17 LNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEE 76
Query: 473 AEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEA-EETIESLNQ 649
A + R+L A A+ WR + E E A E EEA+R+ AR AEA + + +
Sbjct: 77 AAARERAGRELQTAQAQLSEWRRRQEEEAGA-LEAGEEARRR-AAREAEALTQRLAEKTE 134
Query: 650 KVVALEKTKQRLATEVEDLQLEVD 721
V LE+ ++RL E++D L D
Sbjct: 135 TVDRLERGRRRLQQELDDATLSPD 158
Score = 41.9 bits (94), Expect = 0.003
Identities = 41/163 (25%), Positives = 80/163 (49%), Gaps = 10/163 (6%)
Frame = +2
Query: 185 QLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLED 364
+L Q++ + + LN+ ++ +LS E S QL +A+ + + ++ K++L +++
Sbjct: 2 KLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRA 61
Query: 365 TKRLA-------DEEARERATLLGKFRNLEHDLDNIREQVEEEA---EGKADLQRQLSKA 514
+ A +EEA R + + + L R + EEEA E + +R+ ++
Sbjct: 62 MEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAR- 120
Query: 515 NAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESL 643
AEA R ++E V R LE +R+LQ L +A + ++L
Sbjct: 121 EAEALTQRLAEKTETVDR---LERGRRRLQQELDDATLSPDAL 160
Score = 39.9 bits (89), Expect = 0.010
Identities = 34/121 (28%), Positives = 54/121 (44%), Gaps = 3/121 (2%)
Frame = +2
Query: 353 QLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQL 532
+LE+ +E + L + + E L + +E ++EE K L ++ AEA
Sbjct: 9 ELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAG 68
Query: 533 WRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVAL---EKTKQRLATEVED 703
R + E E AR E A R+LQ A+ E ++ AL E+ ++R A E E
Sbjct: 69 LREQLEEEAAAR----ERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEA 124
Query: 704 L 706
L
Sbjct: 125 L 125
Score = 34.7 bits (76), Expect = 0.38
Identities = 29/139 (20%), Positives = 59/139 (42%)
Frame = +2
Query: 83 RAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKL 262
RAQ +E+ ++ L+ ++ K + + QL++ Q E R L + + +
Sbjct: 5 RAQ--AELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAM 62
Query: 263 SIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDL 442
E + L QLEE + + + + QL + +R +EEA R +
Sbjct: 63 EAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREA 122
Query: 443 DNIREQVEEEAEGKADLQR 499
+ + +++ E+ E L+R
Sbjct: 123 EALTQRLAEKTETVDRLER 141
>AF020091-1|AAB69327.1| 622|Homo sapiens smooth muscle myosin heavy
chain SM1 protein.
Length = 622
Score = 77.8 bits (183), Expect = 4e-14
Identities = 62/239 (25%), Positives = 114/239 (47%), Gaps = 5/239 (2%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDH----LSNEKAAQEKIVKQLQHQ 187
+ ++ +Q ++ K EK + + E++DL LD+ +SN + Q K + L +
Sbjct: 51 IENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEE 110
Query: 188 LNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDT 367
N ADE +R +A ++ + L R LEEA +L + L ++ED
Sbjct: 111 KNISSKYADERDRA----EAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDL 166
Query: 368 KRLADEEARERATLLGKFRNLEHDLDNIREQVEE-EAEGKADLQRQLSKANAEAQLWRSK 544
D+ + L R LE ++ ++ Q+EE E E +A +L + Q + +
Sbjct: 167 VSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKL-RLEVNMQALKGQ 225
Query: 545 YESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
+E + AR E+ EE +R+LQ +L E E +E ++ K++L +++DL+L+ D
Sbjct: 226 FERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQAD 284
Score = 69.7 bits (163), Expect = 1e-11
Identities = 54/212 (25%), Positives = 101/212 (47%), Gaps = 1/212 (0%)
Frame = +2
Query: 62 KAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDL 241
K + E AQ E+ + + ++ +S+ K +Q + NE+ ++ A +
Sbjct: 381 KRRLEARIAQLEEELEEEQGNMEAMSDRV---RKATQQAEQLSNELATERSTAQKN---- 433
Query: 242 DAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVS-LTTQLEDTKRLADEEARERATLLGK 418
++A+++L +N +L +L E E V K ++ L ++ + ++EARE+
Sbjct: 434 ESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKS 493
Query: 419 FRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRK 598
+ + L I QVE+E + + Q K NA + + + E E S+ + +RK
Sbjct: 494 LKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLE-EAEEESQRINANRRK 552
Query: 599 LQARLAEAEETIESLNQKVVALEKTKQRLATE 694
LQ L EA E+ E++ ++V AL K+K R E
Sbjct: 553 LQRELDEATESNEAMGREVNAL-KSKLRRGNE 583
Score = 63.3 bits (147), Expect = 9e-10
Identities = 52/234 (22%), Positives = 103/234 (44%), Gaps = 1/234 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDH-LSNEKAAQEKIVKQLQHQLNE 196
+ +M QL++L E + + + L+ + L E+ +QLQ QL+E
Sbjct: 191 MEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHE 250
Query: 197 VQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRL 376
+++ ++ + AAKKKL + DL Q + A + K L Q++D +R
Sbjct: 251 YETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKHVRKLQAQMKDFQRE 310
Query: 377 ADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESE 556
++ R + + E ++ + + E A +R +A+ E + + S
Sbjct: 311 LEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASS 370
Query: 557 GVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEV 718
R+ L++ KR+L+AR+A+ EE +E + A+ ++ + E L E+
Sbjct: 371 LSGRN-ALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNEL 423
Score = 62.5 bits (145), Expect = 2e-09
Identities = 43/188 (22%), Positives = 91/188 (48%)
Frame = +2
Query: 158 EKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIK 337
E+ + L QL++ + K + T+ L+ KK+ E +L +Q EE + +L K K
Sbjct: 13 ERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTK 72
Query: 338 VSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKAN 517
L +L+D D + + + L K R + L + + A+ + + + +
Sbjct: 73 NRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKE 132
Query: 518 AEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEV 697
+A L ++ E + EELE + L+A + + + + + + V LEK+K+ L T++
Sbjct: 133 TKA-LSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQM 191
Query: 698 EDLQLEVD 721
E+++ +++
Sbjct: 192 EEMKTQLE 199
Score = 48.4 bits (110), Expect = 3e-05
Identities = 49/229 (21%), Positives = 100/229 (43%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD 214
E L + + +A+ + + E+ +G + L +EK E + QL+ +L E Q +
Sbjct: 344 EDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNME 403
Query: 215 EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEAR 394
+ + ++LS E + ++ ES QL + L ++L + + +++
Sbjct: 404 AMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAV--KSK 461
Query: 395 ERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSE 574
++T+ LE + + EQVE+EA K + L + + + + + E E +E
Sbjct: 462 FKSTIAA----LEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDER-KMAE 516
Query: 575 ELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
+ +E K AR+ + + +E E+ QR+ LQ E+D
Sbjct: 517 QYKEQAEKGNARVKQLKRQLEEA-------EEESQRINANRRKLQRELD 558
Score = 43.6 bits (98), Expect = 8e-04
Identities = 28/122 (22%), Positives = 55/122 (45%)
Frame = +2
Query: 59 LKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLND 238
+K+K + A +++ L ++ + EK A K +KQ +L E+ + ++ +
Sbjct: 458 VKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQ 517
Query: 239 LDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGK 418
+K + L RQLEEAE + +++ + L +L++ + RE L K
Sbjct: 518 YKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSK 577
Query: 419 FR 424
R
Sbjct: 578 LR 579
>AF013570-1|AAB69326.1| 588|Homo sapiens smooth muscle myosin heavy
chain SM2 protein.
Length = 588
Score = 77.8 bits (183), Expect = 4e-14
Identities = 62/239 (25%), Positives = 114/239 (47%), Gaps = 5/239 (2%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDH----LSNEKAAQEKIVKQLQHQ 187
+ ++ +Q ++ K EK + + E++DL LD+ +SN + Q K + L +
Sbjct: 51 IENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEE 110
Query: 188 LNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDT 367
N ADE +R +A ++ + L R LEEA +L + L ++ED
Sbjct: 111 KNISSKYADERDRA----EAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDL 166
Query: 368 KRLADEEARERATLLGKFRNLEHDLDNIREQVEE-EAEGKADLQRQLSKANAEAQLWRSK 544
D+ + L R LE ++ ++ Q+EE E E +A +L + Q + +
Sbjct: 167 VSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKL-RLEVNMQALKGQ 225
Query: 545 YESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
+E + AR E+ EE +R+LQ +L E E +E ++ K++L +++DL+L+ D
Sbjct: 226 FERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQAD 284
Score = 68.5 bits (160), Expect = 3e-11
Identities = 53/208 (25%), Positives = 100/208 (48%), Gaps = 1/208 (0%)
Frame = +2
Query: 62 KAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDL 241
K + E AQ E+ + + ++ +S+ K +Q + NE+ ++ A +
Sbjct: 381 KRRLEARIAQLEEELEEEQGNMEAMSDRV---RKATQQAEQLSNELATERSTAQKN---- 433
Query: 242 DAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVS-LTTQLEDTKRLADEEARERATLLGK 418
++A+++L +N +L +L E E V K ++ L ++ + ++EARE+
Sbjct: 434 ESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKS 493
Query: 419 FRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRK 598
+ + L I QVE+E + + Q K NA + + + E E S+ + +RK
Sbjct: 494 LKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLE-EAEEESQRINANRRK 552
Query: 599 LQARLAEAEETIESLNQKVVALEKTKQR 682
LQ L EA E+ E++ ++V AL K+K R
Sbjct: 553 LQRELDEATESNEAMGREVNAL-KSKLR 579
Score = 63.3 bits (147), Expect = 9e-10
Identities = 52/234 (22%), Positives = 103/234 (44%), Gaps = 1/234 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDH-LSNEKAAQEKIVKQLQHQLNE 196
+ +M QL++L E + + + L+ + L E+ +QLQ QL+E
Sbjct: 191 MEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHE 250
Query: 197 VQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRL 376
+++ ++ + AAKKKL + DL Q + A + K L Q++D +R
Sbjct: 251 YETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKHVRKLQAQMKDFQRE 310
Query: 377 ADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESE 556
++ R + + E ++ + + E A +R +A+ E + + S
Sbjct: 311 LEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASS 370
Query: 557 GVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEV 718
R+ L++ KR+L+AR+A+ EE +E + A+ ++ + E L E+
Sbjct: 371 LSGRN-ALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNEL 423
Score = 62.5 bits (145), Expect = 2e-09
Identities = 43/188 (22%), Positives = 91/188 (48%)
Frame = +2
Query: 158 EKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIK 337
E+ + L QL++ + K + T+ L+ KK+ E +L +Q EE + +L K K
Sbjct: 13 ERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTK 72
Query: 338 VSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKAN 517
L +L+D D + + + L K R + L + + A+ + + + +
Sbjct: 73 NRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKE 132
Query: 518 AEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEV 697
+A L ++ E + EELE + L+A + + + + + + V LEK+K+ L T++
Sbjct: 133 TKA-LSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQM 191
Query: 698 EDLQLEVD 721
E+++ +++
Sbjct: 192 EEMKTQLE 199
Score = 48.4 bits (110), Expect = 3e-05
Identities = 49/229 (21%), Positives = 100/229 (43%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD 214
E L + + +A+ + + E+ +G + L +EK E + QL+ +L E Q +
Sbjct: 344 EDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNME 403
Query: 215 EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEAR 394
+ + ++LS E + ++ ES QL + L ++L + + +++
Sbjct: 404 AMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAV--KSK 461
Query: 395 ERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSE 574
++T+ LE + + EQVE+EA K + L + + + + + E E +E
Sbjct: 462 FKSTIAA----LEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDER-KMAE 516
Query: 575 ELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
+ +E K AR+ + + +E E+ QR+ LQ E+D
Sbjct: 517 QYKEQAEKGNARVKQLKRQLEEA-------EEESQRINANRRKLQRELD 558
Score = 43.6 bits (98), Expect = 8e-04
Identities = 28/122 (22%), Positives = 55/122 (45%)
Frame = +2
Query: 59 LKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLND 238
+K+K + A +++ L ++ + EK A K +KQ +L E+ + ++ +
Sbjct: 458 VKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQ 517
Query: 239 LDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGK 418
+K + L RQLEEAE + +++ + L +L++ + RE L K
Sbjct: 518 YKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSK 577
Query: 419 FR 424
R
Sbjct: 578 LR 579
>AL832639-1|CAD89954.1| 1331|Homo sapiens hypothetical protein
protein.
Length = 1331
Score = 77.0 bits (181), Expect = 7e-14
Identities = 66/244 (27%), Positives = 113/244 (46%), Gaps = 14/244 (5%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRA------QYFSEV-NDLRAGLD-------HLSNEKAAQEKIVK 172
EQL +L A+AE+ RA Q E+ +DL A ++ HL EK ++ ++
Sbjct: 751 EQLQAETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQ 810
Query: 173 QLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTT 352
+L+ QL E +S + +A KKL E DLL L+ L K +
Sbjct: 811 ELEEQLEEEESARQKLQLEKVTTEAKLKKLEEELDDLLVDLDHQRQSACNLEKKQKKFDQ 870
Query: 353 QLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQL 532
L + K ++ + A ER + R E ++ +EE E KA+L+R + E +
Sbjct: 871 LLAEEKTISAKYAGERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMED 930
Query: 533 WRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQL 712
S + G + ELE++KR L+ ++ E + +E L ++ A E K RL ++ ++
Sbjct: 931 LMSSKDDVGKS-VHELEKSKRALEQQVEEMKTQLEELEGELQATEDAKLRLEVNLQAMKA 989
Query: 713 EVDR 724
+ +R
Sbjct: 990 QFER 993
Score = 65.7 bits (153), Expect = 2e-10
Identities = 49/235 (20%), Positives = 105/235 (44%), Gaps = 1/235 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDH-LSNEKAAQEKIVKQLQHQLNE 196
V +M QL++L E + + + ++A + L E+ KQL Q+ E
Sbjct: 956 VEEMKTQLEELEGELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVRE 1015
Query: 197 VQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRL 376
++++ ++ + + AA+KKL ++ DL ++ A + K L Q++D R
Sbjct: 1016 MEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRE 1075
Query: 377 ADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESE 556
D+ R +L + + E L ++ ++ + E A +R +A E + +
Sbjct: 1076 LDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANS 1135
Query: 557 GVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
+ LEE KR+L+AR+A+ EE +E + ++ +++ + +++
Sbjct: 1136 SGKGALALEE-KRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLN 1189
Score = 62.9 bits (146), Expect = 1e-09
Identities = 59/243 (24%), Positives = 114/243 (46%), Gaps = 13/243 (5%)
Frame = +2
Query: 14 RFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLN 193
R V +M +L+ K ++ A R + ++ DL A +D + + K +++LQ Q+
Sbjct: 1011 RQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMK 1070
Query: 194 EVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQ-LSKIKVSLTTQLEDTK 370
+ + D+ + ++ A K EN L+ +E Q+ + L+ + + ++
Sbjct: 1071 DCMRELDDTRASREEILAQAK----ENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERD 1126
Query: 371 RLADEEARER---ATLLGKFRNLEHDLDNIREQVEEEAEGKADL--------QRQLSKAN 517
LADE A A L + R LE + + E++EEE +G +L Q+ + N
Sbjct: 1127 ELADEIANSSGKGALALEEKRRLEARIAQLEEELEEE-QGNTELINDRLKKANLQIDQIN 1185
Query: 518 AEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIES-LNQKVVALEKTKQRLATE 694
+ L RS + AR ++LE ++L+ +L E E T++S + ALE +L +
Sbjct: 1186 TDLNLERSHAQKNENAR-QQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQ 1244
Query: 695 VED 703
+++
Sbjct: 1245 LDN 1247
Score = 46.8 bits (106), Expect = 9e-05
Identities = 43/196 (21%), Positives = 89/196 (45%), Gaps = 9/196 (4%)
Frame = +2
Query: 155 QEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKI 334
QE+ + + +L +V+ K A L +++ + +L E L QL+ ++ ++
Sbjct: 707 QEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEEL 766
Query: 335 KVSLTTQLEDTKRLAD------EEARERAT-LLGKFRNLEHDLDNIREQVEEEAEGKADL 493
+ LT + ++ + + EE ER L + + ++ ++ + EQ+EEE + L
Sbjct: 767 RARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKL 826
Query: 494 QRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESL--NQKVVALE 667
QL K EA+L K E E +L+ +R+ L + ++ + L +K ++ +
Sbjct: 827 --QLEKVTTEAKL--KKLEEELDDLLVDLDH-QRQSACNLEKKQKKFDQLLAEEKTISAK 881
Query: 668 KTKQRLATEVEDLQLE 715
+R E E + E
Sbjct: 882 YAGERDRAEAEAREKE 897
Score = 41.1 bits (92), Expect = 0.004
Identities = 44/187 (23%), Positives = 79/187 (42%), Gaps = 22/187 (11%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD 214
++ D+L A + A E L A + L E ++ + + +L + + D
Sbjct: 1123 QERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQID 1182
Query: 215 EANRTLN-------DLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVS-LTTQLEDTK 370
+ N LN + A+++L +N +L +L+E E V K ++ L ++ +
Sbjct: 1183 QINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLE 1242
Query: 371 RLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEG------KAD--------LQRQLS 508
D E +ER + R E L ++ QV++E +AD L+RQL
Sbjct: 1243 EQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLE 1302
Query: 509 KANAEAQ 529
+A EAQ
Sbjct: 1303 EAEEEAQ 1309
Score = 37.5 bits (83), Expect = 0.054
Identities = 23/88 (26%), Positives = 41/88 (46%)
Frame = +2
Query: 59 LKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLND 238
+K+K + +++ L LD+ + E+ A K V++ + +L +V + D+ R
Sbjct: 1223 VKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQ 1282
Query: 239 LDAAKKKLSIENSDLLRQLEEAESQVSQ 322
K S L RQLEEAE + +
Sbjct: 1283 YKDQADKASTRLKQLKRQLEEAEEEAQR 1310
>BC000280-1|AAH00280.1| 471|Homo sapiens MYH10 protein protein.
Length = 471
Score = 74.5 bits (175), Expect = 4e-13
Identities = 65/243 (26%), Positives = 109/243 (44%), Gaps = 22/243 (9%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+ + E+L + + AE+ R + E+ + +G L +EK E + QL+ +L E
Sbjct: 184 ILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEE 243
Query: 200 QSKADEANR----------TLN-----------DLDAAKKKLSIENSDLLRQLEEAESQV 316
QS + N TLN D A+++L +N +L +L+E E V
Sbjct: 244 QSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAV 303
Query: 317 SQLSKIKVS-LTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADL 493
K +S L ++ + ++EA+ERA R E L I QVE+E
Sbjct: 304 KSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQY 363
Query: 494 QRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKT 673
+ Q+ KANA + + + E E + ++RKLQ L +A E E L+++V L+
Sbjct: 364 KEQMEKANARMKQLKRQLE-EAEEEATRANASRRKLQRELDDATEANEGLSREVSTLKNR 422
Query: 674 KQR 682
+R
Sbjct: 423 LRR 425
Score = 68.9 bits (161), Expect = 2e-11
Identities = 52/234 (22%), Positives = 105/234 (44%), Gaps = 1/234 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDH-LSNEKAAQEKIVKQLQHQLNE 196
V +M QL++L E + + + ++A + L E+ + L Q+ E
Sbjct: 36 VEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRE 95
Query: 197 VQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRL 376
++++ ++ + A+KKK+ I+ DL Q+E A ++ K L Q++D +R
Sbjct: 96 LEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRE 155
Query: 377 ADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESE 556
+E R + + + E L ++ ++ + E A +R A E + +
Sbjct: 156 LEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNS 215
Query: 557 GVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEV 718
+S L+E KR+L+AR+A+ EE +E + L ++ +V+ L E+
Sbjct: 216 ASGKSALLDE-KRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAEL 268
Score = 57.6 bits (133), Expect = 5e-08
Identities = 53/232 (22%), Positives = 107/232 (46%), Gaps = 3/232 (1%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD 214
E + QL KL+A+ + Y E+ + RA D + + EK +K L+ ++ ++Q +
Sbjct: 137 EVIKQLRKLQAQMK----DYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELA 192
Query: 215 EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEAR 394
+ R A++ E +L ++ + S S L K L ++ + +EE
Sbjct: 193 SSER-------ARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQS 245
Query: 395 ERATLLGKFRNLEHDLDNIREQV--EEEAEGKAD-LQRQLSKANAEAQLWRSKYESEGVA 565
L +FR +D + ++ E A K+D ++QL + N E L E EG
Sbjct: 246 NMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKE--LKAKLQELEGAV 303
Query: 566 RSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
+S + + L+A++ + EE +E ++ A K +R +++++ ++V+
Sbjct: 304 KS-KFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVE 354
Score = 40.7 bits (91), Expect = 0.006
Identities = 25/97 (25%), Positives = 42/97 (43%)
Frame = +2
Query: 53 NKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTL 232
NKL + EK + F +V D R D + +KQL+ QL E + +A AN +
Sbjct: 336 NKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASR 395
Query: 233 NDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVS 343
L + N L R++ ++++ + I S
Sbjct: 396 RKLQRELDDATEANEGLSREVSTLKNRLRRGGPISFS 432
>X06976-1|CAA30039.1| 543|Homo sapiens beta myosin heavy chain (
544 AA) protein.
Length = 543
Score = 73.7 bits (173), Expect = 7e-13
Identities = 51/237 (21%), Positives = 109/237 (45%), Gaps = 1/237 (0%)
Frame = +2
Query: 14 RFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLN 193
R V + LD + + +A + + + ++N++ L H + A +K VK LQ L
Sbjct: 200 RVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLK 259
Query: 194 EVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKR 373
+ Q + D+A R +DL + N+ L +LEE + V Q + + +L +T
Sbjct: 260 DTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLADRELIETSE 319
Query: 374 LADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYES 553
+ +L+ + + ++ DL ++ +VEE + + + + KA +A + + +
Sbjct: 320 RVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKK 379
Query: 554 EGVARSEELEEAKRKLQARLAEAEETIESLNQ-KVVALEKTKQRLATEVEDLQLEVD 721
E S LE K+ ++ + + + ++ Q + +K Q+L V +L+ E++
Sbjct: 380 E-QDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELE 435
Score = 58.8 bits (136), Expect = 2e-08
Identities = 46/235 (19%), Positives = 109/235 (46%), Gaps = 1/235 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+SD+ EQL K + EK R Q +E +L++ L+ +E + + Q + N++
Sbjct: 117 ISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQI 176
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQV-SQLSKIKVSLTTQLEDTKRL 376
+++ + ++ K+ + D L+ +AE++ ++ ++K + L + +
Sbjct: 177 KAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQ 236
Query: 377 ADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESE 556
R A + ++L+ L + + Q+++ DL+ ++ L +++ E E
Sbjct: 237 LSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELE-E 295
Query: 557 GVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
A E+ E +++ L E E ++ L+ + +L K+++ ++ LQ EV+
Sbjct: 296 LRAVVEQTERSRKLADRELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVE 350
Score = 52.0 bits (119), Expect = 2e-06
Identities = 47/217 (21%), Positives = 90/217 (41%), Gaps = 1/217 (0%)
Frame = +2
Query: 74 EKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAK 253
E+ + + V+ L+ LD + + ++ K+++ LNE++ + ANR +
Sbjct: 192 EQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQV 251
Query: 254 KKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNL- 430
K L D QL++A L K +++ + + + EE R + R L
Sbjct: 252 KSLQSLLKDTQIQLDDAVRANDDL-KENIAIVERRNNLLQAELEELRAVVEQTERSRKLA 310
Query: 431 EHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQAR 610
+ +L E+V+ L Q K +A+ +++ E E V EE +K
Sbjct: 311 DRELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVE-EAVQECRNAEEKAKKAITD 369
Query: 611 LAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
A E ++ LE+ K+ + ++DLQ +D
Sbjct: 370 AAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLD 406
Score = 51.6 bits (118), Expect = 3e-06
Identities = 48/215 (22%), Positives = 103/215 (47%), Gaps = 8/215 (3%)
Frame = +2
Query: 101 EVNDLRAGLDHLSNEKAAQ-EKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENS 277
E N ++A ++ EK + E+ + ++ +Q+ D R+ N+ KKK+ + +
Sbjct: 172 EFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLN 231
Query: 278 DLLRQLEEAESQVSQLSKIKVSLTTQLEDTK-RL-----ADEEARERATLLGKFRN-LEH 436
++ QL A ++ K SL + L+DT+ +L A+++ +E ++ + N L+
Sbjct: 232 EMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQA 291
Query: 437 DLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLA 616
+L+ +R VE+ + R+L + + QL S+ S + + ++++ +LQ +
Sbjct: 292 ELEELRAVVEQTERSRKLADRELIETSERVQLLHSQNTSL-INQKKKMDADLSQLQTEVE 350
Query: 617 EAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
EA + + +K +K A E+L+ E D
Sbjct: 351 EAVQECRNAEEKA---KKAITDAAMMAEELKKEQD 382
Score = 50.8 bits (116), Expect = 5e-06
Identities = 23/42 (54%), Positives = 31/42 (73%)
Frame = +2
Query: 599 LQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
L RL EAEE +E++N K +LEKTK RL E+EDL ++V+R
Sbjct: 1 LAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVER 42
Score = 50.0 bits (114), Expect = 9e-06
Identities = 39/169 (23%), Positives = 80/169 (47%), Gaps = 2/169 (1%)
Frame = +2
Query: 29 MGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSN-EKAAQEKIVKQLQHQLNEVQS 205
M E+L + A E+ + + DL+ LD +K +++L+ ++ E+++
Sbjct: 373 MAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEN 432
Query: 206 KADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADE 385
+ + + + +K +L Q EE + +L + L +++ KR A+E
Sbjct: 433 ELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEE 492
Query: 386 EARERATLLGKFRNLEHDLDNIREQVEEEAEGKADL-QRQLSKANAEAQ 529
+ T L KFR ++H+LD EAE +AD+ + Q++K A+++
Sbjct: 493 AEEQANTNLSKFRKVQHELD--------EAEERADIAESQVNKLRAKSR 533
Score = 48.8 bits (111), Expect = 2e-05
Identities = 64/257 (24%), Positives = 116/257 (45%), Gaps = 24/257 (9%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDH-------LSNEKAAQEKIVKQL 178
+++M QL N++ A+A+K S + D + LD L A E+ L
Sbjct: 230 LNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLL 289
Query: 179 QHQLNEVQSKADE-------ANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLS--- 328
Q +L E+++ ++ A+R L + + L +N+ L+ Q ++ ++ +SQL
Sbjct: 290 QAELEELRAVVEQTERSRKLADRELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEV 349
Query: 329 KIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLS 508
+ V E+ + A +A A L K ++ L+ +++ +E+ + DLQ +L
Sbjct: 350 EEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIK---DLQHRLD 406
Query: 509 KANAEAQLWRSKYESEGVARSEELE---EAKRKLQAR----LAEAEETIESLNQKVVALE 667
+A A K + AR ELE EA++K A + ++E I+ L +
Sbjct: 407 EAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDR 466
Query: 668 KTKQRLATEVEDLQLEV 718
K RL V+ LQL+V
Sbjct: 467 KNLLRLQDLVDKLQLKV 483
Score = 44.0 bits (99), Expect = 6e-04
Identities = 37/184 (20%), Positives = 83/184 (45%)
Frame = +2
Query: 158 EKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIK 337
EK +LQ+++ ++ + +N LD ++ ++ ++ EE++S++ K
Sbjct: 23 EKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEA 82
Query: 338 VSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKAN 517
SL+T+L K +E T + +NL+ ++ ++ EQ+ + +L++
Sbjct: 83 RSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKV----- 137
Query: 518 AEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEV 697
R + E+E + LEEA+ L+ + NQ +E+ +LA +
Sbjct: 138 ------RKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIER---KLAEKD 188
Query: 698 EDLQ 709
E+++
Sbjct: 189 EEME 192
Score = 35.1 bits (77), Expect = 0.29
Identities = 25/122 (20%), Positives = 55/122 (45%), Gaps = 1/122 (0%)
Frame = +2
Query: 344 LTTQLEDTKRLADEEARERATLLGKFRN-LEHDLDNIREQVEEEAEGKADLQRQLSKANA 520
L +L++ + A E + + L K ++ L+++++++ VE A L ++ +
Sbjct: 1 LAQRLQEAEE-AVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDK 59
Query: 521 EAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVE 700
W+ KYE E + E ++ R L L + + E + + ++ + L E+
Sbjct: 60 ILAEWKQKYE-ESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEIS 118
Query: 701 DL 706
DL
Sbjct: 119 DL 120
>M21665-1|AAA36345.1| 524|Homo sapiens protein ( Human beta-myosin
heavy chain mRNA, 3' end. ).
Length = 524
Score = 73.7 bits (173), Expect = 7e-13
Identities = 51/237 (21%), Positives = 109/237 (45%), Gaps = 1/237 (0%)
Frame = +2
Query: 14 RFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLN 193
R V + LD + + +A + + + ++N++ L H + A +K VK LQ L
Sbjct: 181 RVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLK 240
Query: 194 EVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKR 373
+ Q + D+A R +DL + N+ L +LEE + V Q + + +L +T
Sbjct: 241 DTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSE 300
Query: 374 LADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYES 553
+ +L+ + + ++ DL ++ +VEE + + + + KA +A + + +
Sbjct: 301 RVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKK 360
Query: 554 EGVARSEELEEAKRKLQARLAEAEETIESLNQ-KVVALEKTKQRLATEVEDLQLEVD 721
E S LE K+ ++ + + + ++ Q + +K Q+L V +L+ E++
Sbjct: 361 E-QDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELE 416
Score = 59.3 bits (137), Expect = 2e-08
Identities = 46/235 (19%), Positives = 110/235 (46%), Gaps = 1/235 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+SD+ EQL K + EK R Q +E +L++ L+ +E + + Q + N++
Sbjct: 98 ISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQI 157
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQV-SQLSKIKVSLTTQLEDTKRL 376
+++ + ++ K+ + D L+ +AE++ ++ ++K + L + +
Sbjct: 158 KAEIERNVAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQ 217
Query: 377 ADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESE 556
R A + ++L+ L + + Q+++ DL+ ++ L +++ E E
Sbjct: 218 LSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELE-E 276
Query: 557 GVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
A E+ E +++ + L E E ++ L+ + +L K+++ ++ LQ EV+
Sbjct: 277 LRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVE 331
Score = 53.2 bits (122), Expect = 1e-06
Identities = 48/217 (22%), Positives = 90/217 (41%), Gaps = 1/217 (0%)
Frame = +2
Query: 74 EKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAK 253
E+ + + V+ L+ LD + + ++ K+++ LNE++ + ANR +
Sbjct: 173 EQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQV 232
Query: 254 KKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNL- 430
K L D QL++A L K +++ + + + EE R + R L
Sbjct: 233 KSLQSLLKDTQIQLDDAVRANDDL-KENIAIVERRNNLLQAELEELRAVVEQTERSRKLA 291
Query: 431 EHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQAR 610
E +L E+V+ L Q K +A+ +++ E E V EE +K
Sbjct: 292 EQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVE-EAVQECRNAEEKAKKAITD 350
Query: 611 LAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
A E ++ LE+ K+ + ++DLQ +D
Sbjct: 351 AAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLD 387
Score = 50.0 bits (114), Expect = 9e-06
Identities = 39/169 (23%), Positives = 80/169 (47%), Gaps = 2/169 (1%)
Frame = +2
Query: 29 MGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSN-EKAAQEKIVKQLQHQLNEVQS 205
M E+L + A E+ + + DL+ LD +K +++L+ ++ E+++
Sbjct: 354 MAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEN 413
Query: 206 KADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADE 385
+ + + + +K +L Q EE + +L + L +++ KR A+E
Sbjct: 414 ELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEE 473
Query: 386 EARERATLLGKFRNLEHDLDNIREQVEEEAEGKADL-QRQLSKANAEAQ 529
+ T L KFR ++H+LD EAE +AD+ + Q++K A+++
Sbjct: 474 AEEQANTNLSKFRKVQHELD--------EAEERADIAESQVNKLRAKSR 514
Score = 48.0 bits (109), Expect = 4e-05
Identities = 61/254 (24%), Positives = 117/254 (46%), Gaps = 21/254 (8%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+++M QL N++ A+A+K S + D + LD ++ + ++ + N +
Sbjct: 211 LNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLL 270
Query: 200 QSKADEANRTLNDLDAAKKKLS---IENSDLLRQLEEAE-SQVSQLSKIKVSLT---TQL 358
Q++ +E + + ++K IE S+ ++ L S ++Q K+ L+ T++
Sbjct: 271 QAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEV 330
Query: 359 EDTK---RLADEEARERAT---LLGKFRNLEHDLDNIREQVEEEAEGKA-DLQRQLSKAN 517
E+ R A+E+A++ T ++ + E D E++++ E DLQ +L +A
Sbjct: 331 EEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAE 390
Query: 518 AEAQLWRSKYESEGVARSEELE---EAKRKLQAR----LAEAEETIESLNQKVVALEKTK 676
A K + AR ELE EA++K A + ++E I+ L + K
Sbjct: 391 QIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNL 450
Query: 677 QRLATEVEDLQLEV 718
RL V+ LQL+V
Sbjct: 451 LRLQDLVDKLQLKV 464
Score = 46.0 bits (104), Expect = 2e-04
Identities = 48/231 (20%), Positives = 100/231 (43%), Gaps = 5/231 (2%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD 214
E L+ L K + + + E++DL L EK+ KQL+ + E+QS +
Sbjct: 79 ESLEHLETFKRENKNLQ----EEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALE 134
Query: 215 EANRTLNDLDAAKKKLSIENSDLLRQLE-EAESQVSQLSKIKVSLTTQLEDTKRLADEEA 391
EA +L + + +E + + ++E + ++ + K + ++ + D E
Sbjct: 135 EAEASLEHEEGKILRAQLEFNQIKAEIERNVAEKDEEMEQAKRNHLRVVDSLQTSLDAET 194
Query: 392 RERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARS 571
R R L + +E DL+ + Q+ A+ Q+Q+ + + + + + + V +
Sbjct: 195 RSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLD-DAVRAN 253
Query: 572 EELEE----AKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQL 712
++L+E +R+ AE EE + Q + + +Q L E +QL
Sbjct: 254 DDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQL 304
Score = 33.5 bits (73), Expect = 0.88
Identities = 19/93 (20%), Positives = 41/93 (44%)
Frame = +2
Query: 428 LEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQA 607
L+++++++ VE A L ++ + W+ KYE E + E ++ R L
Sbjct: 10 LQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYE-ESQSELESSQKEARSLST 68
Query: 608 RLAEAEETIESLNQKVVALEKTKQRLATEVEDL 706
L + + E + + ++ + L E+ DL
Sbjct: 69 ELFKLKNAYEESLEHLETFKRENKNLQEEISDL 101
Score = 32.3 bits (70), Expect = 2.0
Identities = 13/22 (59%), Positives = 18/22 (81%)
Frame = +2
Query: 659 ALEKTKQRLATEVEDLQLEVDR 724
+LEKTK RL E+EDL ++V+R
Sbjct: 2 SLEKTKHRLQNEIEDLMVDVER 23
>M17712-1|AAA36343.1| 543|Homo sapiens protein ( Human cardiac
myosin heavy chain mRNA, 3' end. ).
Length = 543
Score = 73.7 bits (173), Expect = 7e-13
Identities = 51/237 (21%), Positives = 109/237 (45%), Gaps = 1/237 (0%)
Frame = +2
Query: 14 RFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLN 193
R V + LD + + +A + + + ++N++ L H + A +K VK LQ L
Sbjct: 200 RVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLK 259
Query: 194 EVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKR 373
+ Q + D+A R +DL + N+ L +LEE + V Q + + +L +T
Sbjct: 260 DTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLADRELIETSE 319
Query: 374 LADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYES 553
+ +L+ + + ++ DL ++ +VEE + + + + KA +A + + +
Sbjct: 320 RVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKK 379
Query: 554 EGVARSEELEEAKRKLQARLAEAEETIESLNQ-KVVALEKTKQRLATEVEDLQLEVD 721
E S LE K+ ++ + + + ++ Q + +K Q+L V +L+ E++
Sbjct: 380 E-QDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELE 435
Score = 58.8 bits (136), Expect = 2e-08
Identities = 46/235 (19%), Positives = 109/235 (46%), Gaps = 1/235 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+SD+ EQL K + EK R Q +E +L++ L+ +E + + Q + N++
Sbjct: 117 ISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQI 176
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQV-SQLSKIKVSLTTQLEDTKRL 376
+++ + ++ K+ + D L+ +AE++ ++ ++K + L + +
Sbjct: 177 KAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQ 236
Query: 377 ADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESE 556
R A + ++L+ L + + Q+++ DL+ ++ L +++ E E
Sbjct: 237 LSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELE-E 295
Query: 557 GVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
A E+ E +++ L E E ++ L+ + +L K+++ ++ LQ EV+
Sbjct: 296 LRAVVEQTERSRKLADRELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVE 350
Score = 52.0 bits (119), Expect = 2e-06
Identities = 47/217 (21%), Positives = 90/217 (41%), Gaps = 1/217 (0%)
Frame = +2
Query: 74 EKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAK 253
E+ + + V+ L+ LD + + ++ K+++ LNE++ + ANR +
Sbjct: 192 EQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQV 251
Query: 254 KKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNL- 430
K L D QL++A L K +++ + + + EE R + R L
Sbjct: 252 KSLQSLLKDTQIQLDDAVRANDDL-KENIAIVERRNNLLQAELEELRAVVEQTERSRKLA 310
Query: 431 EHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQAR 610
+ +L E+V+ L Q K +A+ +++ E E V EE +K
Sbjct: 311 DRELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVE-EAVQECRNAEEKAKKAITD 369
Query: 611 LAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
A E ++ LE+ K+ + ++DLQ +D
Sbjct: 370 AAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLD 406
Score = 51.6 bits (118), Expect = 3e-06
Identities = 48/215 (22%), Positives = 103/215 (47%), Gaps = 8/215 (3%)
Frame = +2
Query: 101 EVNDLRAGLDHLSNEKAAQ-EKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENS 277
E N ++A ++ EK + E+ + ++ +Q+ D R+ N+ KKK+ + +
Sbjct: 172 EFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLN 231
Query: 278 DLLRQLEEAESQVSQLSKIKVSLTTQLEDTK-RL-----ADEEARERATLLGKFRN-LEH 436
++ QL A ++ K SL + L+DT+ +L A+++ +E ++ + N L+
Sbjct: 232 EMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQA 291
Query: 437 DLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLA 616
+L+ +R VE+ + R+L + + QL S+ S + + ++++ +LQ +
Sbjct: 292 ELEELRAVVEQTERSRKLADRELIETSERVQLLHSQNTSL-INQKKKMDADLSQLQTEVE 350
Query: 617 EAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
EA + + +K +K A E+L+ E D
Sbjct: 351 EAVQECRNAEEKA---KKAITDAAMMAEELKKEQD 382
Score = 50.8 bits (116), Expect = 5e-06
Identities = 23/42 (54%), Positives = 31/42 (73%)
Frame = +2
Query: 599 LQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
L RL EAEE +E++N K +LEKTK RL E+EDL ++V+R
Sbjct: 1 LAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVER 42
Score = 50.0 bits (114), Expect = 9e-06
Identities = 39/169 (23%), Positives = 80/169 (47%), Gaps = 2/169 (1%)
Frame = +2
Query: 29 MGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSN-EKAAQEKIVKQLQHQLNEVQS 205
M E+L + A E+ + + DL+ LD +K +++L+ ++ E+++
Sbjct: 373 MAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEN 432
Query: 206 KADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADE 385
+ + + + +K +L Q EE + +L + L +++ KR A+E
Sbjct: 433 ELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEE 492
Query: 386 EARERATLLGKFRNLEHDLDNIREQVEEEAEGKADL-QRQLSKANAEAQ 529
+ T L KFR ++H+LD EAE +AD+ + Q++K A+++
Sbjct: 493 AEEQANTNLSKFRKVQHELD--------EAEERADIAESQVNKLRAKSR 533
Score = 48.8 bits (111), Expect = 2e-05
Identities = 64/257 (24%), Positives = 116/257 (45%), Gaps = 24/257 (9%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDH-------LSNEKAAQEKIVKQL 178
+++M QL N++ A+A+K S + D + LD L A E+ L
Sbjct: 230 LNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLL 289
Query: 179 QHQLNEVQSKADE-------ANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLS--- 328
Q +L E+++ ++ A+R L + + L +N+ L+ Q ++ ++ +SQL
Sbjct: 290 QAELEELRAVVEQTERSRKLADRELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEV 349
Query: 329 KIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLS 508
+ V E+ + A +A A L K ++ L+ +++ +E+ + DLQ +L
Sbjct: 350 EEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIK---DLQHRLD 406
Query: 509 KANAEAQLWRSKYESEGVARSEELE---EAKRKLQAR----LAEAEETIESLNQKVVALE 667
+A A K + AR ELE EA++K A + ++E I+ L +
Sbjct: 407 EAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDR 466
Query: 668 KTKQRLATEVEDLQLEV 718
K RL V+ LQL+V
Sbjct: 467 KNLLRLQDLVDKLQLKV 483
Score = 44.0 bits (99), Expect = 6e-04
Identities = 37/184 (20%), Positives = 83/184 (45%)
Frame = +2
Query: 158 EKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIK 337
EK +LQ+++ ++ + +N LD ++ ++ ++ EE++S++ K
Sbjct: 23 EKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEA 82
Query: 338 VSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKAN 517
SL+T+L K +E T + +NL+ ++ ++ EQ+ + +L++
Sbjct: 83 RSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKV----- 137
Query: 518 AEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEV 697
R + E+E + LEEA+ L+ + NQ +E+ +LA +
Sbjct: 138 ------RKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIER---KLAEKD 188
Query: 698 EDLQ 709
E+++
Sbjct: 189 EEME 192
Score = 35.1 bits (77), Expect = 0.29
Identities = 25/122 (20%), Positives = 55/122 (45%), Gaps = 1/122 (0%)
Frame = +2
Query: 344 LTTQLEDTKRLADEEARERATLLGKFRN-LEHDLDNIREQVEEEAEGKADLQRQLSKANA 520
L +L++ + A E + + L K ++ L+++++++ VE A L ++ +
Sbjct: 1 LAQRLQEAEE-AVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDK 59
Query: 521 EAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVE 700
W+ KYE E + E ++ R L L + + E + + ++ + L E+
Sbjct: 60 ILAEWKQKYE-ESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEIS 118
Query: 701 DL 706
DL
Sbjct: 119 DL 120
>M25142-1|AAA60387.1| 389|Homo sapiens myosin heavy chain
alpha-subunit protein.
Length = 389
Score = 72.9 bits (171), Expect = 1e-12
Identities = 51/237 (21%), Positives = 108/237 (45%), Gaps = 1/237 (0%)
Frame = +2
Query: 14 RFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLN 193
R V + LD + + + + + + ++N++ L H + A +K VK LQ L
Sbjct: 44 RVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLK 103
Query: 194 EVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKR 373
+ Q + D+A R +DL + N+ L +LEE + V Q + + +L +T
Sbjct: 104 DTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLADRELIETSE 163
Query: 374 LADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYES 553
+ +L+ + + +E DL ++ +VEE + + + + KA +A + + +
Sbjct: 164 RVQLLHSQNTSLINQKKKMEADLTQLQSEVEEAVQECRNAEEKAKKAITDAAMMAEELKK 223
Query: 554 EGVARSEELEEAKRKLQARLAEAEETIESLNQ-KVVALEKTKQRLATEVEDLQLEVD 721
E S LE K+ ++ + + + ++ Q + +K Q+L V +L+ E++
Sbjct: 224 E-QDTSAHLERMKKNIEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEGELE 279
Score = 59.3 bits (137), Expect = 2e-08
Identities = 52/216 (24%), Positives = 102/216 (47%), Gaps = 9/216 (4%)
Frame = +2
Query: 101 EVNDLRAGLDHLSNEKAAQ-EKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKK------ 259
E N ++A ++ EK + E+ + Q ++ +Q+ D R+ N++ KKK
Sbjct: 16 EFNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLN 75
Query: 260 -LSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRN-LE 433
+ I+ S R EA+ QV L + QL+D R A+++ +E ++ + N L+
Sbjct: 76 EMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVR-ANDDLKENIAIVERRNNLLQ 134
Query: 434 HDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARL 613
+L+ +R VE+ + R+L + + QL S+ S + + +++E +LQ+ +
Sbjct: 135 AELEELRAVVEQTERSRKLADRELIETSERVQLLHSQNTSL-INQKKKMEADLTQLQSEV 193
Query: 614 AEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
EA + + +K +K A E+L+ E D
Sbjct: 194 EEAVQECRNAEEKA---KKAITDAAMMAEELKKEQD 226
Score = 51.2 bits (117), Expect = 4e-06
Identities = 65/257 (25%), Positives = 120/257 (46%), Gaps = 24/257 (9%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDH-------LSNEKAAQEKIVKQL 178
+++M QL N++ A+A+K S + D + LD L A E+ L
Sbjct: 74 LNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLL 133
Query: 179 QHQLNEVQSKADE-------ANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQL-SKI 334
Q +L E+++ ++ A+R L + + L +N+ L+ Q ++ E+ ++QL S++
Sbjct: 134 QAELEELRAVVEQTERSRKLADRELIETSERVQLLHSQNTSLINQKKKMEADLTQLQSEV 193
Query: 335 K--VSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLS 508
+ V E+ + A +A A L K ++ L+ +++ +E+ + DLQ +L
Sbjct: 194 EEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNIEQTIK---DLQHRLD 250
Query: 509 KANAEAQLWRSKYESEGVARSEELE---EAKRKLQAR----LAEAEETIESLNQKVVALE 667
+A A K + AR ELE EA++K A + ++E I+ L + +
Sbjct: 251 EAEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDK 310
Query: 668 KTKQRLATEVEDLQLEV 718
K RL V+ LQL+V
Sbjct: 311 KNLLRLQDLVDKLQLKV 327
Score = 50.8 bits (116), Expect = 5e-06
Identities = 48/217 (22%), Positives = 89/217 (41%), Gaps = 1/217 (0%)
Frame = +2
Query: 74 EKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAK 253
E+ + + V+ L+ LD + + ++ K+++ LNE++ + ANR +
Sbjct: 36 EQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQV 95
Query: 254 KKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNL- 430
K L D QL++A L K +++ + + + EE R + R L
Sbjct: 96 KSLQSLLKDTQIQLDDAVRANDDL-KENIAIVERRNNLLQAELEELRAVVEQTERSRKLA 154
Query: 431 EHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQAR 610
+ +L E+V+ L Q K A+ +S+ E E V EE +K
Sbjct: 155 DRELIETSERVQLLHSQNTSLINQKKKMEADLTQLQSEVE-EAVQECRNAEEKAKKAITD 213
Query: 611 LAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
A E ++ LE+ K+ + ++DLQ +D
Sbjct: 214 AAMMAEELKKEQDTSAHLERMKKNIEQTIKDLQHRLD 250
Score = 50.0 bits (114), Expect = 9e-06
Identities = 39/169 (23%), Positives = 80/169 (47%), Gaps = 2/169 (1%)
Frame = +2
Query: 29 MGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSN-EKAAQEKIVKQLQHQLNEVQS 205
M E+L + A E+ + + DL+ LD +K +++L+ ++ E++
Sbjct: 217 MAEELKKEQDTSAHLERMKKNIEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEG 276
Query: 206 KADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADE 385
+ + + + +K +L Q EE + + +L + L +++ KR A+E
Sbjct: 277 ELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLLRLQDLVDKLQLKVKAYKRQAEE 336
Query: 386 EARERATLLGKFRNLEHDLDNIREQVEEEAEGKADL-QRQLSKANAEAQ 529
+ T L KFR ++H+LD EAE +AD+ + Q++K A+++
Sbjct: 337 AEEQANTNLSKFRKVQHELD--------EAEERADIAESQVNKLRAKSR 377
>D86970-1|BAA13206.2| 2067|Homo sapiens KIAA0216 protein.
Length = 2067
Score = 72.9 bits (171), Expect = 1e-12
Identities = 55/238 (23%), Positives = 107/238 (44%)
Frame = +2
Query: 11 GRFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQL 190
G +D E L +LK K ++ A E+ D + L+ EK ++ +L
Sbjct: 1425 GDLQADSEESQRALQQLKKKCQRLTA----ELQDTKLHLEGQQVRNHELEKKQRRFDSEL 1480
Query: 191 NEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTK 370
++ +A L K L E L +QLEE + ++ ++ VSL +L+D
Sbjct: 1481 SQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDIS 1540
Query: 371 RLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYE 550
++ A + + R+LE + + E+++E+A L++ + E + R +
Sbjct: 1541 SQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHS 1600
Query: 551 SEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
E +R EE+EEA++ Q +L + E +E + + + K+ L ++ L +V+R
Sbjct: 1601 KEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNR 1658
Score = 72.1 bits (169), Expect = 2e-12
Identities = 61/240 (25%), Positives = 112/240 (46%), Gaps = 8/240 (3%)
Frame = +2
Query: 14 RFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLN 193
R ++ + QL++ A A K R E+ DL +D ++ K A E+ + +LQ + N
Sbjct: 1696 REIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKN 1755
Query: 194 EVQSKADEANRTLNDL----DAAKKKLS---IENSDLLRQLEEAESQVSQLSKIKVSLTT 352
E+Q++ +E +N+L AA + S + +DL QLEEA + +L + +L +
Sbjct: 1756 EIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQS 1815
Query: 353 QLEDTKR-LADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQ 529
Q+E ++ + D+ R K R LE L+ R QV+ + L+ + K E
Sbjct: 1816 QVEFLEQSMVDKSLVSRQE--AKIRELETRLEFERTQVKRLESLASRLKENMEKLTEE-- 1871
Query: 530 LWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQ 709
+ +A +E ++LQ +L + +E + L +K + K L ++E L+
Sbjct: 1872 ------RDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLE 1925
Score = 46.8 bits (106), Expect = 9e-05
Identities = 51/214 (23%), Positives = 93/214 (43%), Gaps = 2/214 (0%)
Frame = +2
Query: 86 AQYFSEVNDLRAGLD-HLSNEKAAQE-KIVKQLQHQLNEVQSKADEANRTLNDLDAAKKK 259
A+ EV+D AG + L E+A +E K+ Q E + + ++ N K++
Sbjct: 1369 AEINGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQN---------KRQ 1419
Query: 260 LSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHD 439
L DL EE++ + QL K LT +L+DTK + + L K R + +
Sbjct: 1420 LERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSE 1479
Query: 440 LDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAE 619
L E+ + E + LQR+ AEA + + E + + + ++ L+A L +
Sbjct: 1480 LSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVV-SLEAELQD 1538
Query: 620 AEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
+ ++K + L +V+D + E+D
Sbjct: 1539 ISSQESKDEASLAKVKKQLRDLEAKVKDQEEELD 1572
>AY703984-1|AAV80770.1| 1581|Homo sapiens SP-A receptor subunit
SP-R210 alphaS protein.
Length = 1581
Score = 72.9 bits (171), Expect = 1e-12
Identities = 55/238 (23%), Positives = 107/238 (44%)
Frame = +2
Query: 11 GRFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQL 190
G +D E L +LK K ++ A E+ D + L+ EK ++ +L
Sbjct: 954 GDLQADSEESQRALQQLKKKCQRLTA----ELQDTKLHLEGQQVRNHELEKKQRRFDSEL 1009
Query: 191 NEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTK 370
++ +A L K L E L +QLEE + ++ ++ VSL +L+D
Sbjct: 1010 SQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDIS 1069
Query: 371 RLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYE 550
++ A + + R+LE + + E+++E+A L++ + E + R +
Sbjct: 1070 SQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHS 1129
Query: 551 SEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
E +R EE+EEA++ Q +L + E +E + + + K+ L ++ L +V+R
Sbjct: 1130 KEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNR 1187
Score = 72.1 bits (169), Expect = 2e-12
Identities = 61/240 (25%), Positives = 112/240 (46%), Gaps = 8/240 (3%)
Frame = +2
Query: 14 RFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLN 193
R ++ + QL++ A A K R E+ DL +D ++ K A E+ + +LQ + N
Sbjct: 1225 REIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKN 1284
Query: 194 EVQSKADEANRTLNDL----DAAKKKLS---IENSDLLRQLEEAESQVSQLSKIKVSLTT 352
E+Q++ +E +N+L AA + S + +DL QLEEA + +L + +L +
Sbjct: 1285 EIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQS 1344
Query: 353 QLEDTKR-LADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQ 529
Q+E ++ + D+ R K R LE L+ R QV+ + L+ + K E
Sbjct: 1345 QVEFLEQSMVDKSLVSRQE--AKIRELETRLEFERTQVKRLESLASRLKENMEKLTEE-- 1400
Query: 530 LWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQ 709
+ +A +E ++LQ +L + +E + L +K + K L ++E L+
Sbjct: 1401 ------RDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLE 1454
Score = 46.8 bits (106), Expect = 9e-05
Identities = 51/214 (23%), Positives = 93/214 (43%), Gaps = 2/214 (0%)
Frame = +2
Query: 86 AQYFSEVNDLRAGLD-HLSNEKAAQE-KIVKQLQHQLNEVQSKADEANRTLNDLDAAKKK 259
A+ EV+D AG + L E+A +E K+ Q E + + ++ N K++
Sbjct: 898 AEINGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQN---------KRQ 948
Query: 260 LSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHD 439
L DL EE++ + QL K LT +L+DTK + + L K R + +
Sbjct: 949 LERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSE 1008
Query: 440 LDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAE 619
L E+ + E + LQR+ AEA + + E + + + ++ L+A L +
Sbjct: 1009 LSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVV-SLEAELQD 1067
Query: 620 AEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
+ ++K + L +V+D + E+D
Sbjct: 1068 ISSQESKDEASLAKVKKQLRDLEAKVKDQEEELD 1101
Score = 33.9 bits (74), Expect = 0.66
Identities = 28/164 (17%), Positives = 66/164 (40%), Gaps = 4/164 (2%)
Frame = +2
Query: 98 SEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENS 277
+++ +L L+ + E + +L+ + ++ + D+ N K+L +
Sbjct: 1364 AKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLR 1423
Query: 278 DLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIRE 457
D ++ E + ++ S+ K L LE + + + +L+ +++ E
Sbjct: 1424 DTKEEMGELARKEAEASRKKHELEMDLESLEAANQSLQADLKLAFKRIGDLQAAIEDEME 1483
Query: 458 QVEEE----AEGKADLQRQLSKANAEAQLWRSKYESEGVARSEE 577
E E +EG +D+ +L + W SK + A S++
Sbjct: 1484 SDENEDLINSEGDSDVDSELEDRVDGVKSWLSKNKGPSKAASDD 1527
>AB177860-1|BAD66838.1| 1715|Homo sapiens KIAA0216 splice variant 2
protein.
Length = 1715
Score = 72.9 bits (171), Expect = 1e-12
Identities = 55/238 (23%), Positives = 107/238 (44%)
Frame = +2
Query: 11 GRFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQL 190
G +D E L +LK K ++ A E+ D + L+ EK ++ +L
Sbjct: 1088 GDLQADSEESQRALQQLKKKCQRLTA----ELQDTKLHLEGQQVRNHELEKKQRRFDSEL 1143
Query: 191 NEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTK 370
++ +A L K L E L +QLEE + ++ ++ VSL +L+D
Sbjct: 1144 SQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDIS 1203
Query: 371 RLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYE 550
++ A + + R+LE + + E+++E+A L++ + E + R +
Sbjct: 1204 SQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHS 1263
Query: 551 SEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
E +R EE+EEA++ Q +L + E +E + + + K+ L ++ L +V+R
Sbjct: 1264 KEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNR 1321
Score = 72.1 bits (169), Expect = 2e-12
Identities = 61/240 (25%), Positives = 112/240 (46%), Gaps = 8/240 (3%)
Frame = +2
Query: 14 RFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLN 193
R ++ + QL++ A A K R E+ DL +D ++ K A E+ + +LQ + N
Sbjct: 1359 REIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKN 1418
Query: 194 EVQSKADEANRTLNDL----DAAKKKLS---IENSDLLRQLEEAESQVSQLSKIKVSLTT 352
E+Q++ +E +N+L AA + S + +DL QLEEA + +L + +L +
Sbjct: 1419 EIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQS 1478
Query: 353 QLEDTKR-LADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQ 529
Q+E ++ + D+ R K R LE L+ R QV+ + L+ + K E
Sbjct: 1479 QVEFLEQSMVDKSLVSRQE--AKIRELETRLEFERTQVKRLESLASRLKENMEKLTEE-- 1534
Query: 530 LWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQ 709
+ +A +E ++LQ +L + +E + L +K + K L ++E L+
Sbjct: 1535 ------RDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLE 1588
Score = 46.8 bits (106), Expect = 9e-05
Identities = 51/214 (23%), Positives = 93/214 (43%), Gaps = 2/214 (0%)
Frame = +2
Query: 86 AQYFSEVNDLRAGLD-HLSNEKAAQE-KIVKQLQHQLNEVQSKADEANRTLNDLDAAKKK 259
A+ EV+D AG + L E+A +E K+ Q E + + ++ N K++
Sbjct: 1032 AEINGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQN---------KRQ 1082
Query: 260 LSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHD 439
L DL EE++ + QL K LT +L+DTK + + L K R + +
Sbjct: 1083 LERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSE 1142
Query: 440 LDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAE 619
L E+ + E + LQR+ AEA + + E + + + ++ L+A L +
Sbjct: 1143 LSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVV-SLEAELQD 1201
Query: 620 AEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
+ ++K + L +V+D + E+D
Sbjct: 1202 ISSQESKDEASLAKVKKQLRDLEAKVKDQEEELD 1235
Score = 33.9 bits (74), Expect = 0.66
Identities = 28/164 (17%), Positives = 66/164 (40%), Gaps = 4/164 (2%)
Frame = +2
Query: 98 SEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENS 277
+++ +L L+ + E + +L+ + ++ + D+ N K+L +
Sbjct: 1498 AKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLR 1557
Query: 278 DLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIRE 457
D ++ E + ++ S+ K L LE + + + +L+ +++ E
Sbjct: 1558 DTKEEMGELARKEAEASRKKHELEMDLESLEAANQSLQADLKLAFKRIGDLQAAIEDEME 1617
Query: 458 QVEEE----AEGKADLQRQLSKANAEAQLWRSKYESEGVARSEE 577
E E +EG +D+ +L + W SK + A S++
Sbjct: 1618 SDENEDLINSEGDSDVDSELEDRVDGVKSWLSKNKGPSKAASDD 1661
>AB177858-1|BAD66836.1| 2046|Homo sapiens KIAA0216 splice variant 1
protein.
Length = 2046
Score = 72.9 bits (171), Expect = 1e-12
Identities = 55/238 (23%), Positives = 107/238 (44%)
Frame = +2
Query: 11 GRFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQL 190
G +D E L +LK K ++ A E+ D + L+ EK ++ +L
Sbjct: 1404 GDLQADSEESQRALQQLKKKCQRLTA----ELQDTKLHLEGQQVRNHELEKKQRRFDSEL 1459
Query: 191 NEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTK 370
++ +A L K L E L +QLEE + ++ ++ VSL +L+D
Sbjct: 1460 SQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDIS 1519
Query: 371 RLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYE 550
++ A + + R+LE + + E+++E+A L++ + E + R +
Sbjct: 1520 SQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHS 1579
Query: 551 SEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
E +R EE+EEA++ Q +L + E +E + + + K+ L ++ L +V+R
Sbjct: 1580 KEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNR 1637
Score = 72.1 bits (169), Expect = 2e-12
Identities = 61/240 (25%), Positives = 112/240 (46%), Gaps = 8/240 (3%)
Frame = +2
Query: 14 RFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLN 193
R ++ + QL++ A A K R E+ DL +D ++ K A E+ + +LQ + N
Sbjct: 1675 REIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKN 1734
Query: 194 EVQSKADEANRTLNDL----DAAKKKLS---IENSDLLRQLEEAESQVSQLSKIKVSLTT 352
E+Q++ +E +N+L AA + S + +DL QLEEA + +L + +L +
Sbjct: 1735 EIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQS 1794
Query: 353 QLEDTKR-LADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQ 529
Q+E ++ + D+ R K R LE L+ R QV+ + L+ + K E
Sbjct: 1795 QVEFLEQSMVDKSLVSRQE--AKIRELETRLEFERTQVKRLESLASRLKENMEKLTEE-- 1850
Query: 530 LWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQ 709
+ +A +E ++LQ +L + +E + L +K + K L ++E L+
Sbjct: 1851 ------RDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLE 1904
Score = 46.8 bits (106), Expect = 9e-05
Identities = 51/214 (23%), Positives = 93/214 (43%), Gaps = 2/214 (0%)
Frame = +2
Query: 86 AQYFSEVNDLRAGLD-HLSNEKAAQE-KIVKQLQHQLNEVQSKADEANRTLNDLDAAKKK 259
A+ EV+D AG + L E+A +E K+ Q E + + ++ N K++
Sbjct: 1348 AEINGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQN---------KRQ 1398
Query: 260 LSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHD 439
L DL EE++ + QL K LT +L+DTK + + L K R + +
Sbjct: 1399 LERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSE 1458
Query: 440 LDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAE 619
L E+ + E + LQR+ AEA + + E + + + ++ L+A L +
Sbjct: 1459 LSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVV-SLEAELQD 1517
Query: 620 AEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
+ ++K + L +V+D + E+D
Sbjct: 1518 ISSQESKDEASLAKVKKQLRDLEAKVKDQEEELD 1551
>M21664-1|AAA36344.1| 532|Homo sapiens protein ( Human alpha-myosin
heavy chain mRNA, 3' end. ).
Length = 532
Score = 72.1 bits (169), Expect = 2e-12
Identities = 50/237 (21%), Positives = 108/237 (45%), Gaps = 1/237 (0%)
Frame = +2
Query: 14 RFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLN 193
R V + LD + + + + + + ++N++ L H + A +K VK LQ L
Sbjct: 188 RVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLK 247
Query: 194 EVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKR 373
+ Q + D+A R +DL + N+ L +LEE + V Q + + +L +T
Sbjct: 248 DTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSE 307
Query: 374 LADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYES 553
+ +L+ + + ++ DL ++ +VEE + + + + KA +A + + +
Sbjct: 308 RVQLLHSQNTSLINQKKKMDADLSQLQSEVEEAVQECRNAEEKAKKAITDAAMMAEELKK 367
Query: 554 EGVARSEELEEAKRKLQARLAEAEETIESLNQ-KVVALEKTKQRLATEVEDLQLEVD 721
E S LE K+ ++ + + + ++ Q + +K Q+L V +L+ E++
Sbjct: 368 E-QDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEGELE 423
Score = 57.2 bits (132), Expect = 6e-08
Identities = 45/235 (19%), Positives = 107/235 (45%), Gaps = 1/235 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+SD+ EQL + K + EK R Q E +L++ L+ +E + + Q + N++
Sbjct: 105 ISDLTEQLGEGGKNVHELEKVRNQLEVEKMELQSALEEAEASLEHEEGKILRAQLEFNQI 164
Query: 200 QSKAD-EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRL 376
+++ + +++ AK+ L L+ +++ ++K + L + +
Sbjct: 165 KAEIERNVAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQ 224
Query: 377 ADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESE 556
R A + ++L+ L + + Q+++ DL+ ++ L +++ E E
Sbjct: 225 LSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELE-E 283
Query: 557 GVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
A E+ E +++ + L E E ++ L+ + +L K+++ ++ LQ EV+
Sbjct: 284 LRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQSEVE 338
Score = 56.8 bits (131), Expect = 8e-08
Identities = 50/216 (23%), Positives = 103/216 (47%), Gaps = 9/216 (4%)
Frame = +2
Query: 101 EVNDLRAGLDHLSNEKAAQ-EKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKK------ 259
E N ++A ++ EK + E+ + Q ++ +Q+ D R+ N++ KKK
Sbjct: 160 EFNQIKAEIERNVAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLN 219
Query: 260 -LSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRN-LE 433
+ I+ S R EA+ QV L + QL+D R A+++ +E ++ + N L+
Sbjct: 220 EMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVR-ANDDLKENIAIVERRNNLLQ 278
Query: 434 HDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARL 613
+L+ +R VE+ + +++L + + QL S+ S + + ++++ +LQ+ +
Sbjct: 279 AELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSL-INQKKKMDADLSQLQSEV 337
Query: 614 AEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
EA + + +K +K A E+L+ E D
Sbjct: 338 EEAVQECRNAEEKA---KKAITDAAMMAEELKKEQD 370
Score = 54.0 bits (124), Expect = 6e-07
Identities = 44/227 (19%), Positives = 103/227 (45%), Gaps = 2/227 (0%)
Frame = +2
Query: 44 DQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEAN 223
+ +N + EK + + +E+ DL ++ + AA +K + L E + K +E+
Sbjct: 1 EAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQ 60
Query: 224 RTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLED-TKRLADEEARER 400
L + LS E L EE+ + + +L ++ D T++L E +
Sbjct: 61 SELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLG--EGGKN 118
Query: 401 ATLLGKFRN-LEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEE 577
L K RN LE + ++ +EE + ++ +A E +++ E + EE
Sbjct: 119 VHELEKVRNQLEVEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERNVAEKDEE 178
Query: 578 LEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEV 718
+E+AKR Q + + ++++ + + + K+++ ++ ++++++
Sbjct: 179 MEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQL 225
Score = 52.8 bits (121), Expect = 1e-06
Identities = 49/217 (22%), Positives = 90/217 (41%), Gaps = 1/217 (0%)
Frame = +2
Query: 74 EKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAK 253
E+ + + V+ L+ LD + + ++ K+++ LNE++ + ANR +
Sbjct: 180 EQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQV 239
Query: 254 KKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNL- 430
K L D QL++A L K +++ + + + EE R + R L
Sbjct: 240 KSLQSLLKDTQIQLDDAVRANDDL-KENIAIVERRNNLLQAELEELRAVVEQTERSRKLA 298
Query: 431 EHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQAR 610
E +L E+V+ L Q K +A+ +S+ E E V EE +K
Sbjct: 299 EQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQSEVE-EAVQECRNAEEKAKKAITD 357
Query: 611 LAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
A E ++ LE+ K+ + ++DLQ +D
Sbjct: 358 AAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLD 394
Score = 48.4 bits (110), Expect = 3e-05
Identities = 64/257 (24%), Positives = 118/257 (45%), Gaps = 24/257 (9%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDH-------LSNEKAAQEKIVKQL 178
+++M QL N++ A+A+K S + D + LD L A E+ L
Sbjct: 218 LNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLL 277
Query: 179 QHQLNEVQSKADEANRT-------LNDLDAAKKKLSIENSDLLRQLEEAESQVSQL-SKI 334
Q +L E+++ ++ R+ L + + L +N+ L+ Q ++ ++ +SQL S++
Sbjct: 278 QAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQSEV 337
Query: 335 K--VSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLS 508
+ V E+ + A +A A L K ++ L+ +++ +E+ + DLQ +L
Sbjct: 338 EEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIK---DLQHRLD 394
Query: 509 KANAEAQLWRSKYESEGVARSEELE---EAKRKLQAR----LAEAEETIESLNQKVVALE 667
+A A K + AR ELE EA++K A + ++E I+ L + +
Sbjct: 395 EAEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDK 454
Query: 668 KTKQRLATEVEDLQLEV 718
K RL V LQL+V
Sbjct: 455 KNLLRLQDLVNKLQLKV 471
Score = 48.4 bits (110), Expect = 3e-05
Identities = 57/196 (29%), Positives = 91/196 (46%), Gaps = 27/196 (13%)
Frame = +2
Query: 23 SDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLD---HLSNEKAAQEKIVKQLQHQLN 193
S++ E + + + KA+K +L+ D HL K E+ +K LQH+L+
Sbjct: 335 SEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLD 394
Query: 194 EVQSKADEANRT-LNDLDAAKKKLSIE-NSDLLRQLEEAESQVSQLSKIKVSLTTQLEDT 367
E + A + + L L+A ++L E ++ R E + +IK LT Q E+
Sbjct: 395 EAEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSERRIK-ELTYQTEED 453
Query: 368 K----RLAD----------------EEARERA-TLLGKFRNLEHDLDNIREQVEEEAEGK 484
K RL D EEA ERA T L KFR ++H+LD EAE +
Sbjct: 454 KKNLLRLQDLVNKLQLKVKAYKGQAEEAEERANTNLSKFRKVQHELD--------EAEER 505
Query: 485 ADL-QRQLSKANAEAQ 529
AD+ + Q++K A+++
Sbjct: 506 ADIAESQVNKLRAKSR 521
Score = 37.9 bits (84), Expect = 0.041
Identities = 16/30 (53%), Positives = 23/30 (76%)
Frame = +2
Query: 635 ESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
E++N K +LEKTK RL E+EDL ++V+R
Sbjct: 1 EAVNAKCSSLEKTKHRLQNEIEDLMVDVER 30
>BC039612-1|AAH39612.1| 2002|Homo sapiens MYO18A protein protein.
Length = 2002
Score = 72.1 bits (169), Expect = 2e-12
Identities = 61/240 (25%), Positives = 112/240 (46%), Gaps = 8/240 (3%)
Frame = +2
Query: 14 RFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLN 193
R ++ + QL++ A A K R E+ DL +D ++ K A E+ + +LQ + N
Sbjct: 1646 REIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKN 1705
Query: 194 EVQSKADEANRTLNDL----DAAKKKLS---IENSDLLRQLEEAESQVSQLSKIKVSLTT 352
E+Q++ +E +N+L AA + S + +DL QLEEA + +L + +L +
Sbjct: 1706 EIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQS 1765
Query: 353 QLEDTKR-LADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQ 529
Q+E ++ + D+ R K R LE L+ R QV+ + L+ + K E
Sbjct: 1766 QVEFLEQSMVDKSLVSRQE--AKIRELETRLEFERTQVKRLESLASRLKENMEKLTEE-- 1821
Query: 530 LWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQ 709
+ +A +E ++LQ +L + +E + L +K + K L ++E L+
Sbjct: 1822 ------RDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLE 1875
Score = 58.8 bits (136), Expect = 2e-08
Identities = 56/238 (23%), Positives = 105/238 (44%), Gaps = 1/238 (0%)
Frame = +2
Query: 11 GRFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQL 190
G +D E L +LK K ++ A E+ D + L+ EK ++ +L
Sbjct: 1412 GDLQADSEESQRALQQLKKKCQRLTA----ELQDTKLHLEGQQVRNHELEKKQRRFDSEL 1467
Query: 191 NEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTK 370
++ +A L K L E L +QLEE + ++ ++ VSL +L+D
Sbjct: 1468 SQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDIS 1527
Query: 371 RLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYE 550
++ A + + R+LE + + E+++E+A G + QL + E QL +YE
Sbjct: 1528 SQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQA-GTIQMLEQLKQ--MEVQL-EEEYE 1583
Query: 551 SEGVARSEELEEAKRKLQARLAEAEETIESLN-QKVVALEKTKQRLATEVEDLQLEVD 721
+ +++ KR+L+ +LA + + + + L K +R + D QL +D
Sbjct: 1584 DK-----QKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLD 1636
Score = 46.8 bits (106), Expect = 9e-05
Identities = 51/214 (23%), Positives = 93/214 (43%), Gaps = 2/214 (0%)
Frame = +2
Query: 86 AQYFSEVNDLRAGLD-HLSNEKAAQE-KIVKQLQHQLNEVQSKADEANRTLNDLDAAKKK 259
A+ EV+D AG + L E+A +E K+ Q E + + ++ N K++
Sbjct: 1356 AEINGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQN---------KRQ 1406
Query: 260 LSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHD 439
L DL EE++ + QL K LT +L+DTK + + L K R + +
Sbjct: 1407 LERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSE 1466
Query: 440 LDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAE 619
L E+ + E + LQR+ AEA + + E + + + ++ L+A L +
Sbjct: 1467 LSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVV-SLEAELQD 1525
Query: 620 AEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
+ ++K + L +V+D + E+D
Sbjct: 1526 ISSQESKDEASLAKVKKQLRDLEAKVKDQEEELD 1559
Score = 33.9 bits (74), Expect = 0.66
Identities = 28/164 (17%), Positives = 66/164 (40%), Gaps = 4/164 (2%)
Frame = +2
Query: 98 SEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENS 277
+++ +L L+ + E + +L+ + ++ + D+ N K+L +
Sbjct: 1785 AKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLR 1844
Query: 278 DLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIRE 457
D ++ E + ++ S+ K L LE + + + +L+ +++ E
Sbjct: 1845 DTKEEMGELARKEAEASRKKHELEMDLESLEAANQSLQADLKLAFKRIGDLQAAIEDEME 1904
Query: 458 QVEEE----AEGKADLQRQLSKANAEAQLWRSKYESEGVARSEE 577
E E +EG +D+ +L + W SK + A S++
Sbjct: 1905 SDENEDLINSEGDSDVDSELEDRVDGVKSWLSKNKGPSKAASDD 1948
>BC080545-1|AAH80545.1| 498|Homo sapiens MYH11 protein protein.
Length = 498
Score = 69.7 bits (163), Expect = 1e-11
Identities = 54/212 (25%), Positives = 101/212 (47%), Gaps = 1/212 (0%)
Frame = +2
Query: 62 KAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDL 241
K + E AQ E+ + + ++ +S+ K +Q + NE+ ++ A +
Sbjct: 257 KRRLEARIAQLEEELEEEQGNMEAMSDRV---RKATQQAEQLSNELATERSTAQKN---- 309
Query: 242 DAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVS-LTTQLEDTKRLADEEARERATLLGK 418
++A+++L +N +L +L E E V K ++ L ++ + ++EARE+
Sbjct: 310 ESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKS 369
Query: 419 FRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRK 598
+ + L I QVE+E + + Q K NA + + + E E S+ + +RK
Sbjct: 370 LKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLE-EAEEESQRINANRRK 428
Query: 599 LQARLAEAEETIESLNQKVVALEKTKQRLATE 694
LQ L EA E+ E++ ++V AL K+K R E
Sbjct: 429 LQRELDEATESNEAMGREVNAL-KSKLRRGNE 459
Score = 63.7 bits (148), Expect = 7e-10
Identities = 59/241 (24%), Positives = 108/241 (44%), Gaps = 8/241 (3%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDH-LSNEKAAQEKIVKQLQHQLNE 196
+ +M QL++L E + + + L+ + L E+ +QLQ QL+E
Sbjct: 67 MEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHE 126
Query: 197 VQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEA----ESQVSQLSKIKVSL---TTQ 355
+++ ++ + AAKKKL + DL Q + A E + QL K++ + +
Sbjct: 127 YETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRE 186
Query: 356 LEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLW 535
LED + DE K ++LE DL ++E + A +A Q L K +L
Sbjct: 187 LEDARASRDEIFATAKENEKKAKSLEADLMQLQEDL--AAAERARKQADLEKEELAEEL- 243
Query: 536 RSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLE 715
+ ++ L++ KR+L+AR+A+ EE +E + A+ ++ + E L E
Sbjct: 244 -----ASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNE 298
Query: 716 V 718
+
Sbjct: 299 L 299
Score = 61.7 bits (143), Expect = 3e-09
Identities = 43/161 (26%), Positives = 79/161 (49%), Gaps = 1/161 (0%)
Frame = +2
Query: 242 DAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKF 421
+A ++ + L R LEEA +L + L ++ED D+ + L
Sbjct: 1 EAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSK 60
Query: 422 RNLEHDLDNIREQVEE-EAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRK 598
R LE ++ ++ Q+EE E E +A +L + Q + ++E + AR E+ EE +R+
Sbjct: 61 RALETQMEEMKTQLEELEDELQATEDAKL-RLEVNMQALKGQFERDLQARDEQNEEKRRQ 119
Query: 599 LQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
LQ +L E E +E ++ K++L +++DL+L+ D
Sbjct: 120 LQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQAD 160
Score = 48.4 bits (110), Expect = 3e-05
Identities = 49/229 (21%), Positives = 100/229 (43%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD 214
E L + + +A+ + + E+ +G + L +EK E + QL+ +L E Q +
Sbjct: 220 EDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNME 279
Query: 215 EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEAR 394
+ + ++LS E + ++ ES QL + L ++L + + +++
Sbjct: 280 AMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAV--KSK 337
Query: 395 ERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSE 574
++T+ LE + + EQVE+EA K + L + + + + + E E +E
Sbjct: 338 FKSTIAA----LEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDER-KMAE 392
Query: 575 ELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
+ +E K AR+ + + +E E+ QR+ LQ E+D
Sbjct: 393 QYKEQAEKGNARVKQLKRQLEEA-------EEESQRINANRRKLQRELD 434
Score = 43.6 bits (98), Expect = 8e-04
Identities = 28/122 (22%), Positives = 55/122 (45%)
Frame = +2
Query: 59 LKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLND 238
+K+K + A +++ L ++ + EK A K +KQ +L E+ + ++ +
Sbjct: 334 VKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQ 393
Query: 239 LDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGK 418
+K + L RQLEEAE + +++ + L +L++ + RE L K
Sbjct: 394 YKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSK 453
Query: 419 FR 424
R
Sbjct: 454 LR 455
>S67240-1|AAB28951.1| 330|Homo sapiens smooth muscle myosin heavy
chain isoform SM1 protein.
Length = 330
Score = 68.5 bits (160), Expect = 3e-11
Identities = 52/208 (25%), Positives = 95/208 (45%), Gaps = 1/208 (0%)
Frame = +2
Query: 74 EKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAK 253
EK R + + + L L+ A V++ Q ++ ++ T ++A+
Sbjct: 88 EKRRLE--ARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERTTAQKNESAR 145
Query: 254 KKLSIENSDLLRQLEEAESQVSQLSKIKVS-LTTQLEDTKRLADEEARERATLLGKFRNL 430
++L +N +L +L E E V K ++ L ++ + ++EARE+ +
Sbjct: 146 QQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQK 205
Query: 431 EHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQAR 610
+ L I QVE+E + + Q K NA + + + E E S+ + +RKLQ
Sbjct: 206 DKKLKEILLQVEDERKMAEQYKEQAEKGNAGVKQLKRQLE-EAEEESQRINANRRKLQRE 264
Query: 611 LAEAEETIESLNQKVVALEKTKQRLATE 694
L EA E+ E++ ++V AL K+K R E
Sbjct: 265 LDEATESNEAMGREVNAL-KSKLRRGNE 291
Score = 46.4 bits (105), Expect = 1e-04
Identities = 46/229 (20%), Positives = 99/229 (43%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD 214
E L + + +A+ + + E+ +G + L +EK E + QL+ +L E Q +
Sbjct: 52 EDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNME 111
Query: 215 EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEAR 394
+ + ++LS E + ++ ES QL + L ++L + + +++
Sbjct: 112 AMSDRVRKATQQAEQLSNELATERTTAQKNESARQQLERQNKELRSKLHEMEGAV--KSK 169
Query: 395 ERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSE 574
++T+ LE + + EQVE+EA K + L + + + + + E E +
Sbjct: 170 FKSTIAA----LEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQ 225
Query: 575 ELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
E+A++ ++ L +++ E+ QR+ LQ E+D
Sbjct: 226 YKEQAEK--------GNAGVKQLKRQLEEAEEESQRINANRRKLQRELD 266
Score = 42.7 bits (96), Expect = 0.001
Identities = 28/122 (22%), Positives = 55/122 (45%)
Frame = +2
Query: 59 LKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLND 238
+K+K + A +++ L ++ + EK A K +KQ +L E+ + ++ +
Sbjct: 166 VKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQ 225
Query: 239 LDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGK 418
+K + L RQLEEAE + +++ + L +L++ + RE L K
Sbjct: 226 YKEQAEKGNAGVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSK 285
Query: 419 FR 424
R
Sbjct: 286 LR 287
>S67238-1|AAB28950.1| 296|Homo sapiens smooth muscle myosin heavy
chain isoform SM2 protein.
Length = 296
Score = 67.3 bits (157), Expect = 6e-11
Identities = 51/204 (25%), Positives = 94/204 (46%), Gaps = 1/204 (0%)
Frame = +2
Query: 74 EKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAK 253
EK R + + + L L+ A V++ Q ++ ++ T ++A+
Sbjct: 88 EKRRLE--ARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERTTAQKNESAR 145
Query: 254 KKLSIENSDLLRQLEEAESQVSQLSKIKVS-LTTQLEDTKRLADEEARERATLLGKFRNL 430
++L +N +L +L E E V K ++ L ++ + ++EARE+ +
Sbjct: 146 QQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQK 205
Query: 431 EHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQAR 610
+ L I QVE+E + + Q K NA + + + E E S+ + +RKLQ
Sbjct: 206 DKKLKEILLQVEDERKMAEQYKEQAEKGNAGVKQLKRQLE-EAEEESQRINANRRKLQRE 264
Query: 611 LAEAEETIESLNQKVVALEKTKQR 682
L EA E+ E++ ++V AL K+K R
Sbjct: 265 LDEATESNEAMGREVNAL-KSKLR 287
Score = 46.4 bits (105), Expect = 1e-04
Identities = 46/229 (20%), Positives = 99/229 (43%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD 214
E L + + +A+ + + E+ +G + L +EK E + QL+ +L E Q +
Sbjct: 52 EDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNME 111
Query: 215 EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEAR 394
+ + ++LS E + ++ ES QL + L ++L + + +++
Sbjct: 112 AMSDRVRKATQQAEQLSNELATERTTAQKNESARQQLERQNKELRSKLHEMEGAV--KSK 169
Query: 395 ERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSE 574
++T+ LE + + EQVE+EA K + L + + + + + E E +
Sbjct: 170 FKSTIAA----LEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQ 225
Query: 575 ELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
E+A++ ++ L +++ E+ QR+ LQ E+D
Sbjct: 226 YKEQAEK--------GNAGVKQLKRQLEEAEEESQRINANRRKLQRELD 266
Score = 42.7 bits (96), Expect = 0.001
Identities = 28/122 (22%), Positives = 55/122 (45%)
Frame = +2
Query: 59 LKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLND 238
+K+K + A +++ L ++ + EK A K +KQ +L E+ + ++ +
Sbjct: 166 VKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQ 225
Query: 239 LDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGK 418
+K + L RQLEEAE + +++ + L +L++ + RE L K
Sbjct: 226 YKEQAEKGNAGVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSK 285
Query: 419 FR 424
R
Sbjct: 286 LR 287
>BC129803-1|AAI29804.1| 638|Homo sapiens MYH14 protein protein.
Length = 638
Score = 66.5 bits (155), Expect = 1e-10
Identities = 47/228 (20%), Positives = 105/228 (46%), Gaps = 2/228 (0%)
Frame = +2
Query: 41 LDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEA 220
L++ + + + E+ +E+ L + D + E+ + + N+++++ E
Sbjct: 152 LEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTEL 211
Query: 221 NRTLNDLDAAKKKLSIENSDLLRQLE-EAESQVSQLSKIKVSLTTQLEDTKRLADEEARE 397
L + AK +L + L Q E + + + + + L QL D + DEE ++
Sbjct: 212 EDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQ 271
Query: 398 RATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAE-AQLWRSKYESEGVARSE 574
R + + LE +L+ ++ Q+ +GK + +QL K A+ +LWR E+ E
Sbjct: 272 RTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETR--TSRE 329
Query: 575 ELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEV 718
E+ R+ + RL E + L +++ A ++ +++ + +++ EV
Sbjct: 330 EIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEV 377
Score = 62.1 bits (144), Expect = 2e-09
Identities = 55/232 (23%), Positives = 101/232 (43%), Gaps = 2/232 (0%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD 214
EQL++ + +A + +++++ R + + A E+ ++ + + +
Sbjct: 10 EQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLA 69
Query: 215 EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKR--LADEE 388
E T++ L+ +++L E D LE+ VS L K + L + K L E
Sbjct: 70 EKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVE 129
Query: 389 ARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVAR 568
RERA G+ R E ++ +EEE E + +L+RQ AE + S + G +
Sbjct: 130 ERERAEAEGRER--EARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKS- 186
Query: 569 SEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
ELE A R + + + L ++ A E K RL V+ L+ + +R
Sbjct: 187 VHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHER 238
Score = 60.5 bits (140), Expect = 7e-09
Identities = 55/224 (24%), Positives = 105/224 (46%), Gaps = 5/224 (2%)
Frame = +2
Query: 26 DMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQS 205
+M +++ N KA + + Q + L + L E++ E + + + L +V+S
Sbjct: 372 EMADEVANGNLSKAAILEEKRQLEGRLGQLE---EELEEEQSNSELLNDRYRKLLLQVES 428
Query: 206 KADE--ANRTLN-DLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVS-LTTQLEDTKR 373
E A R+ + ++ +++L + +L +L E ++ K+ ++ L ++L +
Sbjct: 429 LTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEE 488
Query: 374 LADEEARERATLLGKF-RNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYE 550
++E RER L GK R E L + QVEEE L+ QL K N + + + E
Sbjct: 489 QLEQETRERI-LSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLE 547
Query: 551 SEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQR 682
E + + +R+LQ L + E+ ES+N++V L +R
Sbjct: 548 -EAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRR 590
Score = 54.0 bits (124), Expect = 6e-07
Identities = 34/100 (34%), Positives = 57/100 (57%), Gaps = 1/100 (1%)
Frame = +2
Query: 428 LEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQA 607
+E + +REQ+EEEA + R+L A A+ WR + E E A E EEA+R+ A
Sbjct: 1 MEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGA-LEAGEEARRR-AA 58
Query: 608 RLAEA-EETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
R AEA + + + V LE+ ++RL E++D +++++
Sbjct: 59 REAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQ 98
Score = 47.2 bits (107), Expect = 7e-05
Identities = 41/195 (21%), Positives = 80/195 (41%), Gaps = 4/195 (2%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGL-DHLSNEKAAQEKIVKQLQHQLNE 196
V + +L AKAE R Q ++ +LR L + + +A + + L+ +L +
Sbjct: 426 VESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQ 485
Query: 197 VQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRL 376
+ + ++ R ++ +++ Q+EE QL +++ KR
Sbjct: 486 AEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQ 545
Query: 377 ADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKA--NAEAQLWRSKYE 550
+E E + R L+ +L+++ E E L+ +L + + R +
Sbjct: 546 LEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFR 605
Query: 551 -SEGVARSEELEEAK 592
EGVA EE EEA+
Sbjct: 606 LEEGVASDEEAEEAQ 620
>AK023943-1|BAB14735.1| 545|Homo sapiens protein ( Homo sapiens
cDNA FLJ13881 fis, clone THYRO1001458, moderately
similar to MYOSIN HEAVY CHAIN, NONMUSCLE TYPE B. ).
Length = 545
Score = 66.5 bits (155), Expect = 1e-10
Identities = 47/228 (20%), Positives = 105/228 (46%), Gaps = 2/228 (0%)
Frame = +2
Query: 41 LDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEA 220
L++ + + + E+ +E+ L + D + E+ + + N+++++ E
Sbjct: 59 LEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTEL 118
Query: 221 NRTLNDLDAAKKKLSIENSDLLRQLE-EAESQVSQLSKIKVSLTTQLEDTKRLADEEARE 397
L + AK +L + L Q E + + + + + L QL D + DEE ++
Sbjct: 119 EDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQ 178
Query: 398 RATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAE-AQLWRSKYESEGVARSE 574
R + + LE +L+ ++ Q+ +GK + +QL K A+ +LWR E+ E
Sbjct: 179 RTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETR--TSRE 236
Query: 575 ELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEV 718
E+ R+ + RL E + L +++ A ++ +++ + +++ EV
Sbjct: 237 EIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEV 284
Score = 60.5 bits (140), Expect = 7e-09
Identities = 55/224 (24%), Positives = 105/224 (46%), Gaps = 5/224 (2%)
Frame = +2
Query: 26 DMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQS 205
+M +++ N KA + + Q + L + L E++ E + + + L +V+S
Sbjct: 279 EMADEVANGNLSKAAILEEKRQLEGRLGQLE---EELEEEQSNSELLNDRYRKLLLQVES 335
Query: 206 KADE--ANRTLN-DLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVS-LTTQLEDTKR 373
E A R+ + ++ +++L + +L +L E ++ K+ ++ L ++L +
Sbjct: 336 LTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEE 395
Query: 374 LADEEARERATLLGKF-RNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYE 550
++E RER L GK R E L + QVEEE L+ QL K N + + + E
Sbjct: 396 QLEQETRERI-LSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLE 454
Query: 551 SEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQR 682
E + + +R+LQ L + E+ ES+N++V L +R
Sbjct: 455 -EAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRR 497
Score = 47.2 bits (107), Expect = 7e-05
Identities = 41/195 (21%), Positives = 80/195 (41%), Gaps = 4/195 (2%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGL-DHLSNEKAAQEKIVKQLQHQLNE 196
V + +L AKAE R Q ++ +LR L + + +A + + L+ +L +
Sbjct: 333 VESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQ 392
Query: 197 VQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRL 376
+ + ++ R ++ +++ Q+EE QL +++ KR
Sbjct: 393 AEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQ 452
Query: 377 ADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKA--NAEAQLWRSKYE 550
+E E + R L+ +L+++ E E L+ +L + + R +
Sbjct: 453 LEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFR 512
Query: 551 -SEGVARSEELEEAK 592
EGVA EE EEA+
Sbjct: 513 LEEGVASDEEAEEAQ 527
Score = 46.4 bits (105), Expect = 1e-04
Identities = 42/146 (28%), Positives = 64/146 (43%), Gaps = 2/146 (1%)
Frame = +2
Query: 293 LEEAESQVSQLSKIKVSLTTQLEDTKR--LADEEARERATLLGKFRNLEHDLDNIREQVE 466
LE+ VS L K + L + K L E RERA G+ R E ++ +E
Sbjct: 3 LEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGRER--EARALSLTRALE 60
Query: 467 EEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLN 646
EE E + +L+RQ AE + S + G + ELE A R + + + L
Sbjct: 61 EEQEAREELERQNRALRAELEALLSSKDDVGKS-VHELERACRVAEQAANDLRAQVTELE 119
Query: 647 QKVVALEKTKQRLATEVEDLQLEVDR 724
++ A E K RL V+ L+ + +R
Sbjct: 120 DELTAAEDAKLRLEVTVQALKTQHER 145
Score = 46.0 bits (104), Expect = 2e-04
Identities = 45/151 (29%), Positives = 79/151 (52%), Gaps = 4/151 (2%)
Frame = +2
Query: 269 ENSDLLRQLEEAESQVSQL-SKIKVSLTTQLEDTKRLADEEARER-ATLLGKFRNLEHDL 442
+ L+ LE+ + + QL ++ K ++ +E+ +R A+ E RER A L R LE +
Sbjct: 5 QQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERER-AEAEGREREARALSLTRALEEE- 62
Query: 443 DNIREQVEEEAEG-KADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAE 619
RE++E + +A+L+ LS ++ + +S +E E R E+A L+A++ E
Sbjct: 63 QEAREELERQNRALRAELEALLS---SKDDVGKSVHELERACR--VAEQAANDLRAQVTE 117
Query: 620 AEETIESLNQKVVALEKTKQRLATEVE-DLQ 709
E+ + + + LE T Q L T+ E DLQ
Sbjct: 118 LEDELTAAEDAKLRLEVTVQALKTQHERDLQ 148
>AK131080-1|BAC85130.1| 563|Homo sapiens FLJ00279 protein protein.
Length = 563
Score = 66.1 bits (154), Expect = 1e-10
Identities = 49/235 (20%), Positives = 105/235 (44%), Gaps = 1/235 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDH-LSNEKAAQEKIVKQLQHQLNE 196
V +M QL++L E + + + ++A + L E+ KQL Q+ E
Sbjct: 137 VEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVRE 196
Query: 197 VQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRL 376
++++ ++ + + AA+KKL ++ DL ++ A + K L Q++D R
Sbjct: 197 MEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRE 256
Query: 377 ADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESE 556
D+ R +L + + E L ++ ++ + E A +R +A E + +
Sbjct: 257 LDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANS 316
Query: 557 GVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
+ LEE KR+L+AR+A+ EE +E + ++ +++ + +++
Sbjct: 317 SGKGALALEE-KRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLN 370
Score = 62.9 bits (146), Expect = 1e-09
Identities = 59/243 (24%), Positives = 114/243 (46%), Gaps = 13/243 (5%)
Frame = +2
Query: 14 RFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLN 193
R V +M +L+ K ++ A R + ++ DL A +D + + K +++LQ Q+
Sbjct: 192 RQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMK 251
Query: 194 EVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQ-LSKIKVSLTTQLEDTK 370
+ + D+ + ++ A K EN L+ +E Q+ + L+ + + ++
Sbjct: 252 DCMRELDDTRASREEILAQAK----ENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERD 307
Query: 371 RLADEEARER---ATLLGKFRNLEHDLDNIREQVEEEAEGKADL--------QRQLSKAN 517
LADE A A L + R LE + + E++EEE +G +L Q+ + N
Sbjct: 308 ELADEIANSSGKGALALEEKRRLEARIAQLEEELEEE-QGNTELINDRLKKANLQIDQIN 366
Query: 518 AEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIES-LNQKVVALEKTKQRLATE 694
+ L RS + AR ++LE ++L+ +L E E T++S + ALE +L +
Sbjct: 367 TDLNLERSHAQKNENAR-QQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQ 425
Query: 695 VED 703
+++
Sbjct: 426 LDN 428
Score = 57.2 bits (132), Expect = 6e-08
Identities = 36/144 (25%), Positives = 73/144 (50%), Gaps = 1/144 (0%)
Frame = +2
Query: 293 LEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEE- 469
LEEA Q ++L ++ T++ED D+ + L R LE ++ ++ Q+EE
Sbjct: 88 LEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEEL 147
Query: 470 EAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQ 649
E E +A +L + Q ++++E + R E+ EE K++L ++ E E +E +
Sbjct: 148 EDELQATEDAKL-RLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERK 206
Query: 650 KVVALEKTKQRLATEVEDLQLEVD 721
+ +++L +++DL+ +D
Sbjct: 207 QRSMAVAARKKLEMDLKDLEAHID 230
Score = 53.2 bits (122), Expect = 1e-06
Identities = 34/122 (27%), Positives = 57/122 (46%)
Frame = +2
Query: 59 LKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLND 238
+K+K + +++ L LD+ + E+ A K V++ + +L +V + D+ R
Sbjct: 404 VKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQ 463
Query: 239 LDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGK 418
K S L RQLEEAE + + + + L +LED AD RE ++L K
Sbjct: 464 YKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKNK 523
Query: 419 FR 424
R
Sbjct: 524 LR 525
Score = 49.6 bits (113), Expect = 1e-05
Identities = 56/238 (23%), Positives = 102/238 (42%), Gaps = 22/238 (9%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD 214
++ D+L A + A E L A + L E ++ + + +L + + D
Sbjct: 304 QERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQID 363
Query: 215 EANRTLN-------DLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVS-LTTQLEDTK 370
+ N LN + A+++L +N +L +L+E E V K ++ L ++ +
Sbjct: 364 QINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLE 423
Query: 371 RLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEG------KAD--------LQRQLS 508
D E +ER + R E L ++ QV++E +AD L+RQL
Sbjct: 424 EQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLE 483
Query: 509 KANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQR 682
+A EAQ ++RKLQ L +A ET +++N++V +L+ +R
Sbjct: 484 EAEEEAQ---------------RANASRRKLQRELEDATETADAMNREVSSLKNKLRR 526
>S67247-1|AAB28952.1| 226|Homo sapiens smooth muscle myosin heavy
chain isoform SMemb protein.
Length = 226
Score = 65.3 bits (152), Expect = 2e-10
Identities = 44/148 (29%), Positives = 73/148 (49%), Gaps = 1/148 (0%)
Frame = +2
Query: 242 DAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVS-LTTQLEDTKRLADEEARERATLLGK 418
D A+++L +N +L +L+E E V K +S L ++ + ++EA+ERA
Sbjct: 34 DNARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKL 93
Query: 419 FRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRK 598
R E L I QVE+E + Q+ KANA + + + E E + ++RK
Sbjct: 94 VRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLE-EAEEEATRANASRRK 152
Query: 599 LQARLAEAEETIESLNQKVVALEKTKQR 682
LQ L +A E E L+++V L+ +R
Sbjct: 153 LQRELDDATEANEGLSREVSTLKNRLRR 180
Score = 53.2 bits (122), Expect = 1e-06
Identities = 29/122 (23%), Positives = 62/122 (50%)
Frame = +2
Query: 59 LKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLND 238
+K+K + + +++ L L+ + E+AA K+V++ + +L E+ + ++ R +
Sbjct: 58 VKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQ 117
Query: 239 LDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGK 418
+K + L RQLEEAE + ++ + + L +L+D + +RE +TL +
Sbjct: 118 YKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEGLSREVSTLKNR 177
Query: 419 FR 424
R
Sbjct: 178 LR 179
Score = 40.7 bits (91), Expect = 0.006
Identities = 25/97 (25%), Positives = 42/97 (43%)
Frame = +2
Query: 53 NKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTL 232
NKL + EK + F +V D R D + +KQL+ QL E + +A AN +
Sbjct: 91 NKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASR 150
Query: 233 NDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVS 343
L + N L R++ ++++ + I S
Sbjct: 151 RKLQRELDDATEANEGLSREVSTLKNRLRRGGPISFS 187
Score = 40.3 bits (90), Expect = 0.008
Identities = 34/164 (20%), Positives = 68/164 (41%), Gaps = 1/164 (0%)
Frame = +2
Query: 26 DMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQS 205
DM D+ K + + A+ +E R+ N + E+ K+L+ +L E++
Sbjct: 1 DMELLNDRFRKTTLQVDTLNAELAAE----RSAAQKSDNARQQLERQNKELKAKLQELEG 56
Query: 206 KA-DEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLAD 382
+ T++ L+A +L + ++ A V + K + Q+ED +R AD
Sbjct: 57 AVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHAD 116
Query: 383 EEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKA 514
+ + + + L+ L+ E+ + LQR+L A
Sbjct: 117 QYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDA 160
>M81105-1|AAA59888.1| 1337|Homo sapiens cellular myosin heavy chain
protein.
Length = 1337
Score = 64.5 bits (150), Expect = 4e-10
Identities = 59/239 (24%), Positives = 117/239 (48%), Gaps = 12/239 (5%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD 214
EQL +L A+AE+ RA+ ++ +L L +E+ + LQ + ++Q
Sbjct: 887 EQLQAETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQ 946
Query: 215 EANRTLNDLDAAKKKLSIENSDL---LRQLEEA----ESQVSQLSKIKVSLTTQL-EDTK 370
E L + ++A++KL +E L++LEE E Q +L+K K L ++ E T
Sbjct: 947 ELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTT 1006
Query: 371 RLADEEARERATLLGKFRNL-EHDLDNIREQVEEEAEGKADLQ---RQLSKANAEAQLWR 538
L +EE E++ L K +N E + ++ E++ E + + +L+ R+L + +
Sbjct: 1007 NLTEEE--EKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQI 1064
Query: 539 SKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLE 715
++ +++ +L + + +LQA LA EE N + + + + +++ EDL+ E
Sbjct: 1065 AELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESE 1123
Score = 59.7 bits (138), Expect = 1e-08
Identities = 47/200 (23%), Positives = 93/200 (46%), Gaps = 10/200 (5%)
Frame = +2
Query: 155 QEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKI 334
QE+ + + +L +V+ K A L +++ + +L E L QL+ ++ ++
Sbjct: 843 QEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEEL 902
Query: 335 KVSLTTQLEDTKRLAD------EEARERAT-LLGKFRNLEHDLDNIREQVEEEAEGKADL 493
+ LT + ++ + + EE ER L + + ++ ++ + EQ+EEE + L
Sbjct: 903 RARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKL 962
Query: 494 QRQLSKANAEAQLWRSKYESEGVARSEE---LEEAKRKLQARLAEAEETIESLNQKVVAL 664
QL K EA+L K E E + ++ L + K+ L+ R+AE + +K +L
Sbjct: 963 --QLEKVTTEAKL--KKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSL 1018
Query: 665 EKTKQRLATEVEDLQLEVDR 724
K K + + DL+ + R
Sbjct: 1019 AKLKNKHEAMITDLEERLRR 1038
Score = 59.7 bits (138), Expect = 1e-08
Identities = 52/221 (23%), Positives = 108/221 (48%), Gaps = 5/221 (2%)
Frame = +2
Query: 62 KAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDL 241
K A K + S++++L+ + L +E+A++ K KQ + E+++ E TL D
Sbjct: 1099 KNMALKKIRELESQISELQ---EDLESERASRNKAEKQKRDLGEELEALKTELEDTL-DS 1154
Query: 242 DAAKKKLSIENS---DLLRQL--EEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERAT 406
AA+++L + ++L++ EEA++ +Q+ +++ + +E+ ++ R +A
Sbjct: 1155 TAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKAN 1214
Query: 407 LLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEE 586
L + LE++ + +V+ +GK D + + K A+ Q + K+ +EG EL +
Sbjct: 1215 LEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKF-NEGERVRTELAD 1273
Query: 587 AKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQ 709
KLQ L + + K L K L ++++D Q
Sbjct: 1274 KVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQ 1314
Score = 54.0 bits (124), Expect = 6e-07
Identities = 44/222 (19%), Positives = 103/222 (46%), Gaps = 2/222 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+S++ E L+ + KAEK + E+ L+ L+ + AAQ+++ + + ++N +
Sbjct: 1113 ISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNIL 1172
Query: 200 QSKADEANRTLN-DLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRL 376
+ +E +T + ++K S +L QLE+ + + L K K +L + +
Sbjct: 1173 KKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANE 1232
Query: 377 ADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESE 556
+ + K + +E L ++ + E + +L +++K E S+
Sbjct: 1233 VKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLL-SQ 1291
Query: 557 GVARSEELEEAKRKLQARLAEAEETIESLNQKVVALE-KTKQ 679
++S +L + L+++L + +E ++ N++ ++L K KQ
Sbjct: 1292 SDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQ 1333
Score = 51.2 bits (117), Expect = 4e-06
Identities = 48/230 (20%), Positives = 91/230 (39%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+ ++ EQL++ + K + + +++ L L ++ K K L+ ++ E
Sbjct: 945 IQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEF 1004
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
+ E L K K +DL +L E Q +L K + L D
Sbjct: 1005 TTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQI 1064
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEG 559
E + A L + E +L +VEEEA K +++ + ++ + ESE
Sbjct: 1065 AELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESER 1124
Query: 560 VARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQ 709
+R+ + E+ KR L L + +E A ++ + + EV L+
Sbjct: 1125 ASRN-KAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILK 1173
>L12579-1|AAA35654.1| 678|Homo sapiens protein ( Human
alternatively spliced CUTL1 mRNA, complete cds. ).
Length = 678
Score = 62.5 bits (145), Expect = 2e-09
Identities = 60/240 (25%), Positives = 110/240 (45%), Gaps = 9/240 (3%)
Frame = +2
Query: 26 DMGEQLD----QLNKLKAKAEKXRAQYFSEVNDLRAGLDHLS-NEKAAQEKIVKQLQHQL 190
D+G+QL +L+ ++ + +K R + E N A + + KA +EKI + Q
Sbjct: 107 DLGQQLQLKVQRLHDIETENQKLR-ETLEEYNKEFAEVKNQEVTIKALKEKIREYEQTLK 165
Query: 191 NEVQSKADEANRTL-NDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDT 367
N+ ++ A E + L ND ++KL +LEEAE +V L T+L D
Sbjct: 166 NQAETIALEKEQKLQNDFAEKERKLQETQMSTTSKLEEAEHKVQSLQTALEKTRTELFDL 225
Query: 368 KRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKY 547
K DEE +A + + DL+ ++ E L+ QLS AN QL
Sbjct: 226 KTKYDEETTAKA---DEIEMIMTDLERANQRAEVAQREAETLREQLSSANHSLQLASQIQ 282
Query: 548 ESEGVARSEEL---EEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEV 718
++ V ++ E+ + +L A+ E + +E + + +L K ++ A+++ L+ ++
Sbjct: 283 KAPDVEQAIEVLTRSSLEVELAAKEREIAQLVEDVQRLQASLTKLRENSASQISQLEQQL 342
Score = 35.5 bits (78), Expect = 0.22
Identities = 37/191 (19%), Positives = 87/191 (45%), Gaps = 4/191 (2%)
Frame = +2
Query: 164 IVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENS----DLLRQLEEAESQVSQLSK 331
++K Q +++ + ++ EA L+ K+ + + + DL +QL+ ++ +
Sbjct: 67 LLKSFQGEIDALSKRSKEAEAAF--LNVYKRLIDVPDPVPALDLGQQLQLKVQRLHDIET 124
Query: 332 IKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSK 511
L LE+ + E + T+ + L+ + + ++ +AE A L+++
Sbjct: 125 ENQKLRETLEEYNKEFAEVKNQEVTI----KALKEKIREYEQTLKNQAETIA-LEKEQKL 179
Query: 512 ANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLAT 691
N A+ R E++ ++ + +LEEA+ K+Q+ E+T L ++ A
Sbjct: 180 QNDFAEKERKLQETQ-MSTTSKLEEAEHKVQSLQTALEKTRTELFDLKTKYDEETTAKAD 238
Query: 692 EVEDLQLEVDR 724
E+E + +++R
Sbjct: 239 EIEMIMTDLER 249
>BC066592-1|AAH66592.1| 1516|Homo sapiens CUTL1 protein protein.
Length = 1516
Score = 62.5 bits (145), Expect = 2e-09
Identities = 60/240 (25%), Positives = 110/240 (45%), Gaps = 9/240 (3%)
Frame = +2
Query: 26 DMGEQLD----QLNKLKAKAEKXRAQYFSEVNDLRAGLDHLS-NEKAAQEKIVKQLQHQL 190
D+G+QL +L+ ++ + +K R + E N A + + KA +EKI + Q
Sbjct: 107 DLGQQLQLKVQRLHDIETENQKLR-ETLEEYNKEFAEVKNQEVTIKALKEKIREYEQTLK 165
Query: 191 NEVQSKADEANRTL-NDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDT 367
N+ ++ A E + L ND ++KL +LEEAE +V L T+L D
Sbjct: 166 NQAETIALEKEQKLQNDFAEKERKLQETQMSTTSKLEEAEHKVQSLQTALEKTRTELFDL 225
Query: 368 KRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKY 547
K DEE +A + + DL+ ++ E L+ QLS AN QL
Sbjct: 226 KTKYDEETTAKA---DEIEMIMTDLERANQRAEVAQREAETLREQLSSANHSLQLASQIQ 282
Query: 548 ESEGVARSEEL---EEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEV 718
++ V ++ E+ + +L A+ E + +E + + +L K ++ A+++ L+ ++
Sbjct: 283 KAPDVEQAIEVLTRSSLEVELAAKEREIAQLVEDVQRLQASLTKLRENSASQISQLEQQL 342
Score = 35.5 bits (78), Expect = 0.22
Identities = 37/191 (19%), Positives = 87/191 (45%), Gaps = 4/191 (2%)
Frame = +2
Query: 164 IVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENS----DLLRQLEEAESQVSQLSK 331
++K Q +++ + ++ EA L+ K+ + + + DL +QL+ ++ +
Sbjct: 67 LLKSFQGEIDALSKRSKEAEAAF--LNVYKRLIDVPDPVPALDLGQQLQLKVQRLHDIET 124
Query: 332 IKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSK 511
L LE+ + E + T+ + L+ + + ++ +AE A L+++
Sbjct: 125 ENQKLRETLEEYNKEFAEVKNQEVTI----KALKEKIREYEQTLKNQAETIA-LEKEQKL 179
Query: 512 ANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLAT 691
N A+ R E++ ++ + +LEEA+ K+Q+ E+T L ++ A
Sbjct: 180 QNDFAEKERKLQETQ-MSTTSKLEEAEHKVQSLQTALEKTRTELFDLKTKYDEETTAKAD 238
Query: 692 EVEDLQLEVDR 724
E+E + +++R
Sbjct: 239 EIEMIMTDLER 249
>AK222832-1|BAD96552.1| 678|Homo sapiens CCAAT displacement protein
isoform b variant protein.
Length = 678
Score = 62.5 bits (145), Expect = 2e-09
Identities = 60/240 (25%), Positives = 110/240 (45%), Gaps = 9/240 (3%)
Frame = +2
Query: 26 DMGEQLD----QLNKLKAKAEKXRAQYFSEVNDLRAGLDHLS-NEKAAQEKIVKQLQHQL 190
D+G+QL +L+ ++ + +K R + E N A + + KA +EKI + Q
Sbjct: 107 DLGQQLQLKVQRLHDIETENQKLR-ETLEEYNKEFAEVKNQEVTIKALKEKIREYEQTLK 165
Query: 191 NEVQSKADEANRTL-NDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDT 367
N+ ++ A E + L ND ++KL +LEEAE +V L T+L D
Sbjct: 166 NQAETIALEKEQKLQNDFAEKERKLQETQMSTTSKLEEAEHKVQSLQTALEKTRTELFDL 225
Query: 368 KRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKY 547
K DEE +A + + DL+ ++ E L+ QLS AN QL
Sbjct: 226 KTKYDEETTAKA---DEIEMIMTDLERANQRAEVAQREAETLREQLSSANHSLQLASQIQ 282
Query: 548 ESEGVARSEEL---EEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEV 718
++ V ++ E+ + +L A+ E + +E + + +L K ++ A+++ L+ ++
Sbjct: 283 KAPDVEQAIEVLTRSSLEVELAAKEREIAQLVEDVQRLQASLTKLRENSASQISQLEQQL 342
Score = 35.5 bits (78), Expect = 0.22
Identities = 37/191 (19%), Positives = 87/191 (45%), Gaps = 4/191 (2%)
Frame = +2
Query: 164 IVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENS----DLLRQLEEAESQVSQLSK 331
++K Q +++ + ++ EA L+ K+ + + + DL +QL+ ++ +
Sbjct: 67 LLKSFQGEIDALSKRSKEAEAAF--LNVYKRLIDVPDPVPALDLGQQLQLKVQRLHDIET 124
Query: 332 IKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSK 511
L LE+ + E + T+ + L+ + + ++ +AE A L+++
Sbjct: 125 ENQKLRETLEEYNKEFAEVKNQEVTI----KALKEKIREYEQTLKNQAETIA-LEKEQKL 179
Query: 512 ANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLAT 691
N A+ R E++ ++ + +LEEA+ K+Q+ E+T L ++ A
Sbjct: 180 QNDFAEKERKLQETQ-MSTTSKLEEAEHKVQSLQTALEKTRTELFDLKTKYDEETTAKAD 238
Query: 692 EVEDLQLEVDR 724
E+E + +++R
Sbjct: 239 EIEMIMTDLER 249
>AC005086-1|AAP22331.1| 317|Homo sapiens unknown protein.
Length = 317
Score = 62.5 bits (145), Expect = 2e-09
Identities = 60/240 (25%), Positives = 110/240 (45%), Gaps = 9/240 (3%)
Frame = +2
Query: 26 DMGEQLD----QLNKLKAKAEKXRAQYFSEVNDLRAGLDHLS-NEKAAQEKIVKQLQHQL 190
D+G+QL +L+ ++ + +K R + E N A + + KA +EKI + Q
Sbjct: 6 DLGQQLQLKVQRLHDIETENQKLR-ETLEEYNKEFAEVKNQEVTIKALKEKIREYEQTLK 64
Query: 191 NEVQSKADEANRTL-NDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDT 367
N+ ++ A E + L ND ++KL +LEEAE +V L T+L D
Sbjct: 65 NQAETIALEKEQKLQNDFAEKERKLQETQMSTTSKLEEAEHKVQSLQTALEKTRTELFDL 124
Query: 368 KRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKY 547
K DEE +A + + DL+ ++ E L+ QLS AN QL
Sbjct: 125 KTKYDEETTAKA---DEIEMIMTDLERANQRAEVAQREAETLREQLSSANHSLQLASQIQ 181
Query: 548 ESEGVARSEEL---EEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEV 718
++ V ++ E+ + +L A+ E + +E + + +L K ++ A+++ L+ ++
Sbjct: 182 KAPDVEQAIEVLTRSSLEVELAAKEREIAQLVEDVQRLQASLTKLRENSASQISQLEQQL 241
Score = 32.3 bits (70), Expect = 2.0
Identities = 31/149 (20%), Positives = 68/149 (45%)
Frame = +2
Query: 278 DLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIRE 457
DL +QL+ ++ + L LE+ + E + T+ + L+ + +
Sbjct: 6 DLGQQLQLKVQRLHDIETENQKLRETLEEYNKEFAEVKNQEVTI----KALKEKIREYEQ 61
Query: 458 QVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIE 637
++ +AE A L+++ N A+ R E++ ++ + +LEEA+ K+Q+ E+T
Sbjct: 62 TLKNQAETIA-LEKEQKLQNDFAEKERKLQETQ-MSTTSKLEEAEHKVQSLQTALEKTRT 119
Query: 638 SLNQKVVALEKTKQRLATEVEDLQLEVDR 724
L ++ A E+E + +++R
Sbjct: 120 ELFDLKTKYDEETTAKADEIEMIMTDLER 148
>BC000676-1|AAH00676.2| 483|Homo sapiens MYH14 protein protein.
Length = 483
Score = 62.1 bits (144), Expect = 2e-09
Identities = 42/189 (22%), Positives = 90/189 (47%), Gaps = 2/189 (1%)
Frame = +2
Query: 158 EKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLE-EAESQVSQLSKI 334
E+ + + N+++++ E L + AK +L + L Q E + + + +
Sbjct: 36 ERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEER 95
Query: 335 KVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKA 514
+ L QL D + DEE ++R + + LE +L+ ++ Q+ +GK + +QL K
Sbjct: 96 RRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKM 155
Query: 515 NAE-AQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLAT 691
A+ +LWR E+ EE+ R+ + RL E + L +++ A ++ +++
Sbjct: 156 QAQMKELWREVEETR--TSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQ 213
Query: 692 EVEDLQLEV 718
+ +++ EV
Sbjct: 214 DRDEMADEV 222
Score = 60.5 bits (140), Expect = 7e-09
Identities = 55/224 (24%), Positives = 105/224 (46%), Gaps = 5/224 (2%)
Frame = +2
Query: 26 DMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQS 205
+M +++ N KA + + Q + L + L E++ E + + + L +V+S
Sbjct: 217 EMADEVANGNLSKAAILEEKRQLEGRLGQLE---EELEEEQSNSELLNDRYRKLLLQVES 273
Query: 206 KADE--ANRTLN-DLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVS-LTTQLEDTKR 373
E A R+ + ++ +++L + +L +L E ++ K+ ++ L ++L +
Sbjct: 274 LTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEE 333
Query: 374 LADEEARERATLLGKF-RNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYE 550
++E RER L GK R E L + QVEEE L+ QL K N + + + E
Sbjct: 334 QLEQETRERI-LSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLE 392
Query: 551 SEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQR 682
E + + +R+LQ L + E+ ES+N++V L +R
Sbjct: 393 -EAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRR 435
Score = 47.2 bits (107), Expect = 7e-05
Identities = 41/195 (21%), Positives = 80/195 (41%), Gaps = 4/195 (2%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGL-DHLSNEKAAQEKIVKQLQHQLNE 196
V + +L AKAE R Q ++ +LR L + + +A + + L+ +L +
Sbjct: 271 VESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQ 330
Query: 197 VQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRL 376
+ + ++ R ++ +++ Q+EE QL +++ KR
Sbjct: 331 AEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQ 390
Query: 377 ADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKA--NAEAQLWRSKYE 550
+E E + R L+ +L+++ E E L+ +L + + R +
Sbjct: 391 LEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFR 450
Query: 551 -SEGVARSEELEEAK 592
EGVA EE EEA+
Sbjct: 451 LEEGVASDEEAEEAQ 465
>BC118918-1|AAI18919.1| 1302|Homo sapiens cingulin-like 1 protein.
Length = 1302
Score = 61.7 bits (143), Expect = 3e-09
Identities = 58/198 (29%), Positives = 87/198 (43%), Gaps = 9/198 (4%)
Frame = +2
Query: 158 EKIVKQLQHQLNEVQSKADEANRT--LNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSK 331
EKI Q N T + DL K KL+IE ++L RQL+ + +
Sbjct: 583 EKIQTLKSRAAGSAQGNNQACNSTSEVKDLLEQKSKLTIEVAELQRQLQLEVKNQQNIKE 642
Query: 332 IKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDL-DNIRE--QVEEEAEGKA----D 490
+ + LE+ + +E+ E +TL + E +L N+ E QV+ E E D
Sbjct: 643 ERERMRANLEELRSQHNEKVEENSTLQQRLEESEGELRKNLEELFQVKMEREQHQTEIRD 702
Query: 491 LQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEK 670
LQ QLS+ + E + + E A EEL +AK+ LQ L EE + L ++ L
Sbjct: 703 LQDQLSEMHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIAKEEQEDLLRKRERELTA 762
Query: 671 TKQRLATEVEDLQLEVDR 724
K L EV E+D+
Sbjct: 763 LKGALKEEVSSHDQEMDK 780
Score = 58.4 bits (135), Expect = 3e-08
Identities = 49/218 (22%), Positives = 98/218 (44%), Gaps = 1/218 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+ D+ +L+ + LK + Q +V+ L L+ N + + + + Q+ ++
Sbjct: 1042 LKDLEYELEAKSHLKDDRSRLVKQMEDKVSQLEMELEEERNNSDLLSERISRSREQMEQL 1101
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAE-SQVSQLSKIKVSLTTQLEDTKRL 376
+++ + DL+ K L +N DL ++ E S S + V + ++ + +
Sbjct: 1102 RNELLQERAARQDLECDKISLERQNKDLKSRIIHLEGSYRSSKEGLVVQMEARIAELEDR 1161
Query: 377 ADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESE 556
+ E R+RA L R LE + + QV++E D + QLS + + + E E
Sbjct: 1162 LESEERDRANLQLSNRRLERKVKELVMQVDDEHLSLTDQKDQLS---LRLKAMKRQVE-E 1217
Query: 557 GVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEK 670
+ LE +K+KLQ L E + E L ++ +++K
Sbjct: 1218 AEEEIDRLESSKKKLQRELEEQMDMNEHLQGQLNSMKK 1255
Score = 54.4 bits (125), Expect = 4e-07
Identities = 53/236 (22%), Positives = 99/236 (41%), Gaps = 11/236 (4%)
Frame = +2
Query: 29 MGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSK 208
+ E D+L+ K ++ + E+ + L L K QE ++++ + +L ++
Sbjct: 707 LSEMHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIAKEEQEDLLRKRERELTALKGA 766
Query: 209 A-DEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADE 385
+E + ++D K++ E L +EEA V L+ + T+
Sbjct: 767 LKEEVSSHDQEMDKLKEQYDAELQALRESVEEATKNVEVLASRSNTSEQDQAGTEMRVKL 826
Query: 386 EARERATLLGKFRNLEHDLDNIREQVEE----EAEGKADLQ------RQLSKANAEAQLW 535
E L G+ LE + ++ Q+E+ EA+ K L+ RQL +A A+
Sbjct: 827 LQEENEKLQGRSEELERRVAQLQRQIEDLKGDEAKAKETLKKYEGEIRQLEEALVHARKE 886
Query: 536 RSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVED 703
+ S A ELE A+ L E ++ E L ++ E+ + RL E+E+
Sbjct: 887 EKEAVSARRALENELEAAQGNLSQTTQEQKQLSEKLKEESEQKEQLR-RLKNEMEN 941
Score = 52.4 bits (120), Expect = 2e-06
Identities = 58/233 (24%), Positives = 110/233 (47%), Gaps = 4/233 (1%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVND--LRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSK 208
E +QL++ K K + A+ ++ + L A L+ K E ++ ++ +L + Q
Sbjct: 970 ELQNQLDEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDE--MRLMEEELRDYQRA 1027
Query: 209 ADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEE 388
DEA L+ K L E + L++ S++ + + KVS QLE + EE
Sbjct: 1028 QDEALTKRQLLEQTLKDLEYE-LEAKSHLKDDRSRLVKQMEDKVS---QLE----MELEE 1079
Query: 389 ARERATLLG-KFRNLEHDLDNIREQVEEEAEGKADLQ-RQLSKANAEAQLWRSKYESEGV 562
R + LL + ++ +R ++ +E + DL+ ++S L EG
Sbjct: 1080 ERNNSDLLSERISRSREQMEQLRNELLQERAARQDLECDKISLERQNKDLKSRIIHLEGS 1139
Query: 563 ARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
RS + E +++AR+AE E+ +ES + L+ + +RL +V++L ++VD
Sbjct: 1140 YRSSK-EGLVVQMEARIAELEDRLESEERDRANLQLSNRRLERKVKELVMQVD 1191
Score = 50.4 bits (115), Expect = 7e-06
Identities = 52/253 (20%), Positives = 111/253 (43%), Gaps = 14/253 (5%)
Frame = +2
Query: 2 NSAGRFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQ 181
N A S++ + L+Q +KL + + + Q EV + + ++ E+ +++L+
Sbjct: 600 NQACNSTSEVKDLLEQKSKLTIEVAELQRQLQLEVKNQQ----NIKEERERMRANLEELR 655
Query: 182 HQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLE 361
Q NE + + L + + +K E + + E+ ++++ L + +L+
Sbjct: 656 SQHNEKVEENSTLQQRLEESEGELRKNLEELFQVKMEREQHQTEIRDLQDQLSEMHDELD 715
Query: 362 DTKRLADEEARERATLLGKFRNLEHDL-----------DNIREQVEEEAEGKADLQRQLS 508
KR D RE+ L+ + + DL D +R++ E K L+ ++S
Sbjct: 716 SAKRSED---REKGALIEELLQAKQDLQDLLIAKEEQEDLLRKRERELTALKGALKEEVS 772
Query: 509 KANAEAQLWRSKYESEGVARSEELEEAKRK---LQARLAEAEETIESLNQKVVALEKTKQ 679
+ E + +Y++E A E +EEA + L +R +E+ +V L++ +
Sbjct: 773 SHDQEMDKLKEQYDAELQALRESVEEATKNVEVLASRSNTSEQDQAGTEMRVKLLQEENE 832
Query: 680 RLATEVEDLQLEV 718
+L E+L+ V
Sbjct: 833 KLQGRSEELERRV 845
>BC112049-1|AAI12050.1| 1302|Homo sapiens cingulin-like 1 protein.
Length = 1302
Score = 61.7 bits (143), Expect = 3e-09
Identities = 58/198 (29%), Positives = 87/198 (43%), Gaps = 9/198 (4%)
Frame = +2
Query: 158 EKIVKQLQHQLNEVQSKADEANRT--LNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSK 331
EKI Q N T + DL K KL+IE ++L RQL+ + +
Sbjct: 583 EKIQTLKSRAAGSAQGNNQACNSTSEVKDLLEQKSKLTIEVAELQRQLQLEVKNQQNIKE 642
Query: 332 IKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDL-DNIRE--QVEEEAEGKA----D 490
+ + LE+ + +E+ E +TL + E +L N+ E QV+ E E D
Sbjct: 643 ERERMRANLEELRSQHNEKVEENSTLQQRLEESEGELRKNLEELFQVKMEREQHQTEIRD 702
Query: 491 LQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEK 670
LQ QLS+ + E + + E A EEL +AK+ LQ L EE + L ++ L
Sbjct: 703 LQDQLSEMHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIAKEEQEDLLRKRERELTA 762
Query: 671 TKQRLATEVEDLQLEVDR 724
K L EV E+D+
Sbjct: 763 LKGALKEEVSSHDQEMDK 780
Score = 58.4 bits (135), Expect = 3e-08
Identities = 49/218 (22%), Positives = 98/218 (44%), Gaps = 1/218 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+ D+ +L+ + LK + Q +V+ L L+ N + + + + Q+ ++
Sbjct: 1042 LKDLEYELEAKSHLKDDRSRLVKQMEDKVSQLEMELEEERNNSDLLSERISRSREQMEQL 1101
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAE-SQVSQLSKIKVSLTTQLEDTKRL 376
+++ + DL+ K L +N DL ++ E S S + V + ++ + +
Sbjct: 1102 RNELLQERAARQDLECDKISLERQNKDLKSRIIHLEGSYRSSKEGLVVQMEARIAELEDR 1161
Query: 377 ADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESE 556
+ E R+RA L R LE + + QV++E D + QLS + + + E E
Sbjct: 1162 LESEERDRANLQLSNRRLERKVKELVMQVDDEHLSLTDQKDQLS---LRLKAMKRQVE-E 1217
Query: 557 GVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEK 670
+ LE +K+KLQ L E + E L ++ +++K
Sbjct: 1218 AEEEIDRLESSKKKLQRELEEQMDMNEHLQGQLNSMKK 1255
Score = 54.4 bits (125), Expect = 4e-07
Identities = 53/236 (22%), Positives = 99/236 (41%), Gaps = 11/236 (4%)
Frame = +2
Query: 29 MGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSK 208
+ E D+L+ K ++ + E+ + L L K QE ++++ + +L ++
Sbjct: 707 LSEMHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIAKEEQEDLLRKRERELTALKGA 766
Query: 209 A-DEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADE 385
+E + ++D K++ E L +EEA V L+ + T+
Sbjct: 767 LKEEVSSHDQEMDKLKEQYDAELQALRESVEEATKNVEVLASRSNTSEQDQAGTEMRVKL 826
Query: 386 EARERATLLGKFRNLEHDLDNIREQVEE----EAEGKADLQ------RQLSKANAEAQLW 535
E L G+ LE + ++ Q+E+ EA+ K L+ RQL +A A+
Sbjct: 827 LQEENEKLQGRSEELERRVAQLQRQIEDLKGDEAKAKETLKKYEGEIRQLEEALVHARKE 886
Query: 536 RSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVED 703
+ S A ELE A+ L E ++ E L ++ E+ + RL E+E+
Sbjct: 887 EKEAVSARRALENELEAAQGNLSQTTQEQKQLSEKLKEESEQKEQLR-RLKNEMEN 941
Score = 52.4 bits (120), Expect = 2e-06
Identities = 58/233 (24%), Positives = 110/233 (47%), Gaps = 4/233 (1%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVND--LRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSK 208
E +QL++ K K + A+ ++ + L A L+ K E ++ ++ +L + Q
Sbjct: 970 ELQNQLDEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDE--MRLMEEELRDYQRA 1027
Query: 209 ADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEE 388
DEA L+ K L E + L++ S++ + + KVS QLE + EE
Sbjct: 1028 QDEALTKRQLLEQTLKDLEYE-LEAKSHLKDDRSRLVKQMEDKVS---QLE----MELEE 1079
Query: 389 ARERATLLG-KFRNLEHDLDNIREQVEEEAEGKADLQ-RQLSKANAEAQLWRSKYESEGV 562
R + LL + ++ +R ++ +E + DL+ ++S L EG
Sbjct: 1080 ERNNSDLLSERISRSREQMEQLRNELLQERAARQDLECDKISLERQNKDLKSRIIHLEGS 1139
Query: 563 ARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
RS + E +++AR+AE E+ +ES + L+ + +RL +V++L ++VD
Sbjct: 1140 YRSSK-EGLVVQMEARIAELEDRLESEERDRANLQLSNRRLERKVKELVMQVD 1191
Score = 50.4 bits (115), Expect = 7e-06
Identities = 52/253 (20%), Positives = 111/253 (43%), Gaps = 14/253 (5%)
Frame = +2
Query: 2 NSAGRFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQ 181
N A S++ + L+Q +KL + + + Q EV + + ++ E+ +++L+
Sbjct: 600 NQACNSTSEVKDLLEQKSKLTIEVAELQRQLQLEVKNQQ----NIKEERERMRANLEELR 655
Query: 182 HQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLE 361
Q NE + + L + + +K E + + E+ ++++ L + +L+
Sbjct: 656 SQHNEKVEENSTLQQRLEESEGELRKNLEELFQVKMEREQHQTEIRDLQDQLSEMHDELD 715
Query: 362 DTKRLADEEARERATLLGKFRNLEHDL-----------DNIREQVEEEAEGKADLQRQLS 508
KR D RE+ L+ + + DL D +R++ E K L+ ++S
Sbjct: 716 SAKRSED---REKGALIEELLQAKQDLQDLLIAKEEQEDLLRKRERELTALKGALKEEVS 772
Query: 509 KANAEAQLWRSKYESEGVARSEELEEAKRK---LQARLAEAEETIESLNQKVVALEKTKQ 679
+ E + +Y++E A E +EEA + L +R +E+ +V L++ +
Sbjct: 773 SHDQEMDKLKEQYDAELQALRESVEEATKNVEVLASRSNTSEQDQAGTEMRVKLLQEENE 832
Query: 680 RLATEVEDLQLEV 718
+L E+L+ V
Sbjct: 833 KLQGRSEELERRV 845
>BC093827-1|AAH93827.1| 1302|Homo sapiens cingulin-like 1 protein.
Length = 1302
Score = 61.7 bits (143), Expect = 3e-09
Identities = 58/198 (29%), Positives = 87/198 (43%), Gaps = 9/198 (4%)
Frame = +2
Query: 158 EKIVKQLQHQLNEVQSKADEANRT--LNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSK 331
EKI Q N T + DL K KL+IE ++L RQL+ + +
Sbjct: 583 EKIQTLKSRAAGSAQGNNQACNSTSEVKDLLEQKSKLTIEVAELQRQLQLEVKNQQNIKE 642
Query: 332 IKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDL-DNIRE--QVEEEAEGKA----D 490
+ + LE+ + +E+ E +TL + E +L N+ E QV+ E E D
Sbjct: 643 ERERMRANLEELRSQHNEKVEENSTLQQRLEESEGELRKNLEELFQVKMEREQHQTEIRD 702
Query: 491 LQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEK 670
LQ QLS+ + E + + E A EEL +AK+ LQ L EE + L ++ L
Sbjct: 703 LQDQLSEMHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIAKEEQEDLLRKRERELTA 762
Query: 671 TKQRLATEVEDLQLEVDR 724
K L EV E+D+
Sbjct: 763 LKGALKEEVSSHDQEMDK 780
Score = 58.4 bits (135), Expect = 3e-08
Identities = 49/218 (22%), Positives = 98/218 (44%), Gaps = 1/218 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+ D+ +L+ + LK + Q +V+ L L+ N + + + + Q+ ++
Sbjct: 1042 LKDLEYELEAKSHLKDDRSRLVKQMEDKVSQLEMELEEERNNSDLLSERISRSREQMEQL 1101
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAE-SQVSQLSKIKVSLTTQLEDTKRL 376
+++ + DL+ K L +N DL ++ E S S + V + ++ + +
Sbjct: 1102 RNELLQERAARQDLECDKISLERQNKDLKSRIIHLEGSYRSSKEGLVVQMEARIAELEDR 1161
Query: 377 ADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESE 556
+ E R+RA L R LE + + QV++E D + QLS + + + E E
Sbjct: 1162 LESEERDRANLQLSNRRLERKVKELVMQVDDEHLSLTDQKDQLS---LRLKAMKRQVE-E 1217
Query: 557 GVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEK 670
+ LE +K+KLQ L E + E L ++ +++K
Sbjct: 1218 AEEEIDRLESSKKKLQRELEEQMDMNEHLQGQLNSMKK 1255
Score = 54.4 bits (125), Expect = 4e-07
Identities = 53/236 (22%), Positives = 99/236 (41%), Gaps = 11/236 (4%)
Frame = +2
Query: 29 MGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSK 208
+ E D+L+ K ++ + E+ + L L K QE ++++ + +L ++
Sbjct: 707 LSEMHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIAKEEQEDLLRKRERELTALKGA 766
Query: 209 A-DEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADE 385
+E + ++D K++ E L +EEA V L+ + T+
Sbjct: 767 LKEEVSSHDQEMDKLKEQYDAELQALRESVEEATKNVEVLASRSNTSEQDQAGTEMRVKL 826
Query: 386 EARERATLLGKFRNLEHDLDNIREQVEE----EAEGKADLQ------RQLSKANAEAQLW 535
E L G+ LE + ++ Q+E+ EA+ K L+ RQL +A A+
Sbjct: 827 LQEENEKLQGRSEELERRVAQLQRQIEDLKGDEAKAKETLKKYEGEIRQLEEALVHARKE 886
Query: 536 RSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVED 703
+ S A ELE A+ L E ++ E L ++ E+ + RL E+E+
Sbjct: 887 EKEAVSARRALENELEAAQGNLSQTTQEQKQLSEKLKEESEQKEQLR-RLKNEMEN 941
Score = 52.4 bits (120), Expect = 2e-06
Identities = 58/233 (24%), Positives = 110/233 (47%), Gaps = 4/233 (1%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVND--LRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSK 208
E +QL++ K K + A+ ++ + L A L+ K E ++ ++ +L + Q
Sbjct: 970 ELQNQLDEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDE--MRLMEEELRDYQRA 1027
Query: 209 ADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEE 388
DEA L+ K L E + L++ S++ + + KVS QLE + EE
Sbjct: 1028 QDEALTKRQLLEQTLKDLEYE-LEAKSHLKDDRSRLVKQMEDKVS---QLE----MELEE 1079
Query: 389 ARERATLLG-KFRNLEHDLDNIREQVEEEAEGKADLQ-RQLSKANAEAQLWRSKYESEGV 562
R + LL + ++ +R ++ +E + DL+ ++S L EG
Sbjct: 1080 ERNNSDLLSERISRSREQMEQLRNELLQERAARQDLECDKISLERQNKDLKSRIIHLEGS 1139
Query: 563 ARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
RS + E +++AR+AE E+ +ES + L+ + +RL +V++L ++VD
Sbjct: 1140 YRSSK-EGLVVQMEARIAELEDRLESEERDRANLQLSNRRLERKVKELVMQVD 1191
Score = 50.4 bits (115), Expect = 7e-06
Identities = 52/253 (20%), Positives = 111/253 (43%), Gaps = 14/253 (5%)
Frame = +2
Query: 2 NSAGRFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQ 181
N A S++ + L+Q +KL + + + Q EV + + ++ E+ +++L+
Sbjct: 600 NQACNSTSEVKDLLEQKSKLTIEVAELQRQLQLEVKNQQ----NIKEERERMRANLEELR 655
Query: 182 HQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLE 361
Q NE + + L + + +K E + + E+ ++++ L + +L+
Sbjct: 656 SQHNEKVEENSTLQQRLEESEGELRKNLEELFQVKMEREQHQTEIRDLQDQLSEMHDELD 715
Query: 362 DTKRLADEEARERATLLGKFRNLEHDL-----------DNIREQVEEEAEGKADLQRQLS 508
KR D RE+ L+ + + DL D +R++ E K L+ ++S
Sbjct: 716 SAKRSED---REKGALIEELLQAKQDLQDLLIAKEEQEDLLRKRERELTALKGALKEEVS 772
Query: 509 KANAEAQLWRSKYESEGVARSEELEEAKRK---LQARLAEAEETIESLNQKVVALEKTKQ 679
+ E + +Y++E A E +EEA + L +R +E+ +V L++ +
Sbjct: 773 SHDQEMDKLKEQYDAELQALRESVEEATKNVEVLASRSNTSEQDQAGTEMRVKLLQEENE 832
Query: 680 RLATEVEDLQLEV 718
+L E+L+ V
Sbjct: 833 KLQGRSEELERRV 845
>AY274808-1|AAP42073.1| 1302|Homo sapiens KIAA1749 protein protein.
Length = 1302
Score = 61.7 bits (143), Expect = 3e-09
Identities = 58/198 (29%), Positives = 87/198 (43%), Gaps = 9/198 (4%)
Frame = +2
Query: 158 EKIVKQLQHQLNEVQSKADEANRT--LNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSK 331
EKI Q N T + DL K KL+IE ++L RQL+ + +
Sbjct: 583 EKIQTLKSRAAGSAQGNNQACNSTSEVKDLLEQKSKLTIEVAELQRQLQLEVKNQQNIKE 642
Query: 332 IKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDL-DNIRE--QVEEEAEGKA----D 490
+ + LE+ + +E+ E +TL + E +L N+ E QV+ E E D
Sbjct: 643 ERERMRANLEELRSQHNEKVEENSTLQQRLEESEGELRKNLEELFQVKMEREQHQTEIRD 702
Query: 491 LQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEK 670
LQ QLS+ + E + + E A EEL +AK+ LQ L EE + L ++ L
Sbjct: 703 LQDQLSEMHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIAKEEQEDLLRKRERELTA 762
Query: 671 TKQRLATEVEDLQLEVDR 724
K L EV E+D+
Sbjct: 763 LKGALKEEVSSHDQEMDK 780
Score = 58.4 bits (135), Expect = 3e-08
Identities = 49/218 (22%), Positives = 98/218 (44%), Gaps = 1/218 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+ D+ +L+ + LK + Q +V+ L L+ N + + + + Q+ ++
Sbjct: 1042 LKDLEYELEAKSHLKDDRSRLVKQMEDKVSQLEMELEEERNNSDLLSERISRSREQMEQL 1101
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAE-SQVSQLSKIKVSLTTQLEDTKRL 376
+++ + DL+ K L +N DL ++ E S S + V + ++ + +
Sbjct: 1102 RNELLQERAARQDLECDKISLERQNKDLKSRIIHLEGSYRSSKEGLVVQMEARIAELEDR 1161
Query: 377 ADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESE 556
+ E R+RA L R LE + + QV++E D + QLS + + + E E
Sbjct: 1162 LESEERDRANLQLSNRRLERKVKELVMQVDDEHLSLTDQKDQLS---LRLKAMKRQVE-E 1217
Query: 557 GVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEK 670
+ LE +K+KLQ L E + E L ++ +++K
Sbjct: 1218 AEEEIDRLESSKKKLQRELEEQMDMNEHLQGQLNSMKK 1255
Score = 54.4 bits (125), Expect = 4e-07
Identities = 53/236 (22%), Positives = 99/236 (41%), Gaps = 11/236 (4%)
Frame = +2
Query: 29 MGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSK 208
+ E D+L+ K ++ + E+ + L L K QE ++++ + +L ++
Sbjct: 707 LSEMHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIAKEEQEDLLRKRERELTALKGA 766
Query: 209 A-DEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADE 385
+E + ++D K++ E L +EEA V L+ + T+
Sbjct: 767 LKEEVSSHDQEMDKLKEQYDAELQALRESVEEATKNVEVLASRSNTSEQDQAGTEMRVKL 826
Query: 386 EARERATLLGKFRNLEHDLDNIREQVEE----EAEGKADLQ------RQLSKANAEAQLW 535
E L G+ LE + ++ Q+E+ EA+ K L+ RQL +A A+
Sbjct: 827 LQEENEKLQGRSEELERRVAQLQRQIEDLKGDEAKAKETLKKYEGEIRQLEEALVHARKE 886
Query: 536 RSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVED 703
+ S A ELE A+ L E ++ E L ++ E+ + RL E+E+
Sbjct: 887 EKEAVSARRALENELEAAQGNLSQTTQEQKQLSEKLKEESEQKEQLR-RLKNEMEN 941
Score = 52.4 bits (120), Expect = 2e-06
Identities = 58/233 (24%), Positives = 110/233 (47%), Gaps = 4/233 (1%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVND--LRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSK 208
E +QL++ K K + A+ ++ + L A L+ K E ++ ++ +L + Q
Sbjct: 970 ELQNQLDEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDE--MRLMEEELRDYQRA 1027
Query: 209 ADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEE 388
DEA L+ K L E + L++ S++ + + KVS QLE + EE
Sbjct: 1028 QDEALTKRQLLEQTLKDLEYE-LEAKSHLKDDRSRLVKQMEDKVS---QLE----MELEE 1079
Query: 389 ARERATLLG-KFRNLEHDLDNIREQVEEEAEGKADLQ-RQLSKANAEAQLWRSKYESEGV 562
R + LL + ++ +R ++ +E + DL+ ++S L EG
Sbjct: 1080 ERNNSDLLSERISRSREQMEQLRNELLQERAARQDLECDKISLERQNKDLKSRIIHLEGS 1139
Query: 563 ARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
RS + E +++AR+AE E+ +ES + L+ + +RL +V++L ++VD
Sbjct: 1140 YRSSK-EGLVVQMEARIAELEDRLESEERDRANLQLSNRRLERKVKELVMQVD 1191
Score = 50.4 bits (115), Expect = 7e-06
Identities = 52/253 (20%), Positives = 111/253 (43%), Gaps = 14/253 (5%)
Frame = +2
Query: 2 NSAGRFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQ 181
N A S++ + L+Q +KL + + + Q EV + + ++ E+ +++L+
Sbjct: 600 NQACNSTSEVKDLLEQKSKLTIEVAELQRQLQLEVKNQQ----NIKEERERMRANLEELR 655
Query: 182 HQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLE 361
Q NE + + L + + +K E + + E+ ++++ L + +L+
Sbjct: 656 SQHNEKVEENSTLQQRLEESEGELRKNLEELFQVKMEREQHQTEIRDLQDQLSEMHDELD 715
Query: 362 DTKRLADEEARERATLLGKFRNLEHDL-----------DNIREQVEEEAEGKADLQRQLS 508
KR D RE+ L+ + + DL D +R++ E K L+ ++S
Sbjct: 716 SAKRSED---REKGALIEELLQAKQDLQDLLIAKEEQEDLLRKRERELTALKGALKEEVS 772
Query: 509 KANAEAQLWRSKYESEGVARSEELEEAKRK---LQARLAEAEETIESLNQKVVALEKTKQ 679
+ E + +Y++E A E +EEA + L +R +E+ +V L++ +
Sbjct: 773 SHDQEMDKLKEQYDAELQALRESVEEATKNVEVLASRSNTSEQDQAGTEMRVKLLQEENE 832
Query: 680 RLATEVEDLQLEV 718
+L E+L+ V
Sbjct: 833 KLQGRSEELERRV 845
>AK056673-1|BAB71249.1| 883|Homo sapiens protein ( Homo sapiens cDNA
FLJ32111 fis, clone OCBBF2001528, weakly similar to
MYOSIN HEAVY CHAIN, SMOOTH MUSCLE ISOFORM. ).
Length = 883
Score = 61.7 bits (143), Expect = 3e-09
Identities = 58/198 (29%), Positives = 87/198 (43%), Gaps = 9/198 (4%)
Frame = +2
Query: 158 EKIVKQLQHQLNEVQSKADEANRT--LNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSK 331
EKI Q N T + DL K KL+IE ++L RQL+ + +
Sbjct: 583 EKIQTLKSRAAGSAQGNNQACNSTSEVKDLLEQKSKLTIEVAELQRQLQLEVKNQQNIKE 642
Query: 332 IKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDL-DNIRE--QVEEEAEGKA----D 490
+ + LE+ + +E+ E +TL + E +L N+ E QV+ E E D
Sbjct: 643 ERERMRANLEELRSQHNEKVEENSTLQQRLEESEGELRKNLEELFQVKMEREQHQTEIRD 702
Query: 491 LQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEK 670
LQ QLS+ + E + + E A EEL +AK+ LQ L EE + L ++ L
Sbjct: 703 LQDQLSEMHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIAKEEQEDLLRKRERELTA 762
Query: 671 TKQRLATEVEDLQLEVDR 724
K L EV E+D+
Sbjct: 763 LKGALKEEVSSHDQEMDK 780
Score = 49.6 bits (113), Expect = 1e-05
Identities = 52/253 (20%), Positives = 110/253 (43%), Gaps = 14/253 (5%)
Frame = +2
Query: 2 NSAGRFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQ 181
N A S++ + L+Q +KL + + + Q EV + + ++ E+ +++L+
Sbjct: 600 NQACNSTSEVKDLLEQKSKLTIEVAELQRQLQLEVKNQQ----NIKEERERMRANLEELR 655
Query: 182 HQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLE 361
Q NE + + L + + +K E + + E+ ++++ L + +L+
Sbjct: 656 SQHNEKVEENSTLQQRLEESEGELRKNLEELFQVKMEREQHQTEIRDLQDQLSEMHDELD 715
Query: 362 DTKRLADEEARERATLLGKFRNLEHDL-----------DNIREQVEEEAEGKADLQRQLS 508
KR D RE+ L+ + + DL D +R++ E K L+ ++S
Sbjct: 716 SAKRSED---REKGALIEELLQAKQDLQDLLIAKEEQEDLLRKRERELTALKGALKEEVS 772
Query: 509 KANAEAQLWRSKYESEGVARSEELEEAKRK---LQARLAEAEETIESLNQKVVALEKTKQ 679
+ E + +Y++E A E +EEA + L +R +E+ +V L++ +
Sbjct: 773 SHDQEMDKLKEQYDAELQALRESVEEATKNVEVLASRSNTSEQDQAGTEMRVKLLQEENE 832
Query: 680 RLATEVEDLQLEV 718
L E+L+ V
Sbjct: 833 NLQGRSEELERRV 845
>AB051536-1|BAB21840.2| 1047|Homo sapiens KIAA1749 protein protein.
Length = 1047
Score = 61.7 bits (143), Expect = 3e-09
Identities = 58/198 (29%), Positives = 87/198 (43%), Gaps = 9/198 (4%)
Frame = +2
Query: 158 EKIVKQLQHQLNEVQSKADEANRT--LNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSK 331
EKI Q N T + DL K KL+IE ++L RQL+ + +
Sbjct: 328 EKIQTLKSRAAGSAQGNNQACNSTSEVKDLLEQKSKLTIEVAELQRQLQLEVKNQQNIKE 387
Query: 332 IKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDL-DNIRE--QVEEEAEGKA----D 490
+ + LE+ + +E+ E +TL + E +L N+ E QV+ E E D
Sbjct: 388 ERERMRANLEELRSQHNEKVEENSTLQQRLEESEGELRKNLEELFQVKMEREQHQTEIRD 447
Query: 491 LQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEK 670
LQ QLS+ + E + + E A EEL +AK+ LQ L EE + L ++ L
Sbjct: 448 LQDQLSEMHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIAKEEQEDLLRKRERELTA 507
Query: 671 TKQRLATEVEDLQLEVDR 724
K L EV E+D+
Sbjct: 508 LKGALKEEVSSHDQEMDK 525
Score = 59.7 bits (138), Expect = 1e-08
Identities = 50/218 (22%), Positives = 98/218 (44%), Gaps = 1/218 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+ D+ +L+ + LK + Q +V+ L L+ N + + + + Q+ +V
Sbjct: 787 LKDLEYELEAKSHLKDDRSRLVKQMEDKVSQLEMELEEERNNSDLLSERISRSREQMEQV 846
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAE-SQVSQLSKIKVSLTTQLEDTKRL 376
+++ + DL+ K L +N DL ++ E S S + V + ++ + +
Sbjct: 847 RNELLQERAARQDLECDKISLERQNKDLKSRIIHLEGSYRSSKEGLVVQMEARIAELEDR 906
Query: 377 ADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESE 556
+ E R+RA L R LE + + QV++E D + QLS + + + E E
Sbjct: 907 LESEERDRANLQLSNRRLERKVKELVMQVDDEHLSLTDQKDQLS---LRLKAMKRQVE-E 962
Query: 557 GVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEK 670
+ LE +K+KLQ L E + E L ++ +++K
Sbjct: 963 AEEEIDRLESSKKKLQRELEEQMDMNEHLQGQLNSMKK 1000
Score = 54.4 bits (125), Expect = 4e-07
Identities = 53/236 (22%), Positives = 99/236 (41%), Gaps = 11/236 (4%)
Frame = +2
Query: 29 MGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSK 208
+ E D+L+ K ++ + E+ + L L K QE ++++ + +L ++
Sbjct: 452 LSEMHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIAKEEQEDLLRKRERELTALKGA 511
Query: 209 A-DEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADE 385
+E + ++D K++ E L +EEA V L+ + T+
Sbjct: 512 LKEEVSSHDQEMDKLKEQYDAELQALRESVEEATKNVEVLASRSNTSEQDQAGTEMRVKL 571
Query: 386 EARERATLLGKFRNLEHDLDNIREQVEE----EAEGKADLQ------RQLSKANAEAQLW 535
E L G+ LE + ++ Q+E+ EA+ K L+ RQL +A A+
Sbjct: 572 LQEENEKLQGRSEELERRVAQLQRQIEDLKGDEAKAKETLKKYEGEIRQLEEALVHARKE 631
Query: 536 RSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVED 703
+ S A ELE A+ L E ++ E L ++ E+ + RL E+E+
Sbjct: 632 EKEAVSARRALENELEAAQGNLSQTTQEQKQLSEKLKEESEQKEQLR-RLKNEMEN 686
Score = 52.8 bits (121), Expect = 1e-06
Identities = 58/233 (24%), Positives = 110/233 (47%), Gaps = 4/233 (1%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVND--LRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSK 208
E +QL++ K K + A+ ++ + L A L+ K E ++ ++ +L + Q
Sbjct: 715 ELQNQLDEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDE--MRLMEEELRDYQRA 772
Query: 209 ADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEE 388
DEA L+ K L E + L++ S++ + + KVS QLE + EE
Sbjct: 773 QDEALTKRQLLEQTLKDLEYE-LEAKSHLKDDRSRLVKQMEDKVS---QLE----MELEE 824
Query: 389 ARERATLLG-KFRNLEHDLDNIREQVEEEAEGKADLQ-RQLSKANAEAQLWRSKYESEGV 562
R + LL + ++ +R ++ +E + DL+ ++S L EG
Sbjct: 825 ERNNSDLLSERISRSREQMEQVRNELLQERAARQDLECDKISLERQNKDLKSRIIHLEGS 884
Query: 563 ARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
RS + E +++AR+AE E+ +ES + L+ + +RL +V++L ++VD
Sbjct: 885 YRSSK-EGLVVQMEARIAELEDRLESEERDRANLQLSNRRLERKVKELVMQVD 936
Score = 50.4 bits (115), Expect = 7e-06
Identities = 52/253 (20%), Positives = 111/253 (43%), Gaps = 14/253 (5%)
Frame = +2
Query: 2 NSAGRFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQ 181
N A S++ + L+Q +KL + + + Q EV + + ++ E+ +++L+
Sbjct: 345 NQACNSTSEVKDLLEQKSKLTIEVAELQRQLQLEVKNQQ----NIKEERERMRANLEELR 400
Query: 182 HQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLE 361
Q NE + + L + + +K E + + E+ ++++ L + +L+
Sbjct: 401 SQHNEKVEENSTLQQRLEESEGELRKNLEELFQVKMEREQHQTEIRDLQDQLSEMHDELD 460
Query: 362 DTKRLADEEARERATLLGKFRNLEHDL-----------DNIREQVEEEAEGKADLQRQLS 508
KR D RE+ L+ + + DL D +R++ E K L+ ++S
Sbjct: 461 SAKRSED---REKGALIEELLQAKQDLQDLLIAKEEQEDLLRKRERELTALKGALKEEVS 517
Query: 509 KANAEAQLWRSKYESEGVARSEELEEAKRK---LQARLAEAEETIESLNQKVVALEKTKQ 679
+ E + +Y++E A E +EEA + L +R +E+ +V L++ +
Sbjct: 518 SHDQEMDKLKEQYDAELQALRESVEEATKNVEVLASRSNTSEQDQAGTEMRVKLLQEENE 577
Query: 680 RLATEVEDLQLEV 718
+L E+L+ V
Sbjct: 578 KLQGRSEELERRV 590
>BC025422-1|AAH25422.1| 676|Homo sapiens cut-like 1, CCAAT
displacement protein (Drosophila) protein.
Length = 676
Score = 61.3 bits (142), Expect = 4e-09
Identities = 62/239 (25%), Positives = 110/239 (46%), Gaps = 8/239 (3%)
Frame = +2
Query: 26 DMGEQLD----QLNKLKAKAEKXRAQYFSEVNDLRAGLDHLS-NEKAAQEKIVKQLQHQL 190
D+G+QL +L+ ++ + +K R + E N A + + KA +EKI + Q
Sbjct: 107 DLGQQLQLKVQRLHDIETENQKLR-ETLEEYNKEFAEVKNQEVTIKALKEKIREYEQTLK 165
Query: 191 NEVQSKADEANRTL-NDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDT 367
N+ ++ A E + L ND ++KL +LEEAE +V L T+L D
Sbjct: 166 NQAETIALEKEQKLQNDFAEKERKLQETQMSTTSKLEEAEHKVQSLQTALEKTRTELFDL 225
Query: 368 KRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKY 547
K DEE +A + + DL+ ++ E L+ QLS AN QL
Sbjct: 226 KTKYDEETTAKA---DEIEMIMTDLERANQRAEVAQREAETLREQLSSANHSLQLASQIQ 282
Query: 548 ESEGVARSEELEEA--KRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEV 718
++ VA E L + + +L A+ E + +E + + +L K ++ A+++ L+ ++
Sbjct: 283 KAPDVA-IEVLTRSSLEVELAAKEREIAQLVEDVQRLQASLTKLRENSASQISQLEQQL 340
Score = 35.5 bits (78), Expect = 0.22
Identities = 37/191 (19%), Positives = 87/191 (45%), Gaps = 4/191 (2%)
Frame = +2
Query: 164 IVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENS----DLLRQLEEAESQVSQLSK 331
++K Q +++ + ++ EA L+ K+ + + + DL +QL+ ++ +
Sbjct: 67 LLKSFQGEIDALSKRSKEAEAAF--LNVYKRLIDVPDPVPALDLGQQLQLKVQRLHDIET 124
Query: 332 IKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSK 511
L LE+ + E + T+ + L+ + + ++ +AE A L+++
Sbjct: 125 ENQKLRETLEEYNKEFAEVKNQEVTI----KALKEKIREYEQTLKNQAETIA-LEKEQKL 179
Query: 512 ANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLAT 691
N A+ R E++ ++ + +LEEA+ K+Q+ E+T L ++ A
Sbjct: 180 QNDFAEKERKLQETQ-MSTTSKLEEAEHKVQSLQTALEKTRTELFDLKTKYDEETTAKAD 238
Query: 692 EVEDLQLEVDR 724
E+E + +++R
Sbjct: 239 EIEMIMTDLER 249
>Y09420-1|CAA70574.1| 400|Homo sapiens huntingtin interacting
protein protein.
Length = 400
Score = 60.5 bits (140), Expect = 7e-09
Identities = 59/221 (26%), Positives = 101/221 (45%), Gaps = 9/221 (4%)
Frame = +2
Query: 14 RFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLN 193
R V + + +L A+ + R Q + LRA LD L ++ EK Q L+
Sbjct: 156 RVVLQLKGHVSELEADLAEQQHLRQQAADDCEFLRAELDELRRQREDTEKA----QRSLS 211
Query: 194 EVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSL---TTQLED 364
E++ KA + + L +L ++DLLR+ E QVS + +V L +LED
Sbjct: 212 EIERKAQANEQRYSKLKEKYSELVQNHADLLRKNAEVTKQVSMARQAQVDLEREKKELED 271
Query: 365 T-KRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKAN-----AEA 526
+ +R++D+ R+ L +L+ +L + ++ + +G + Q S+AN AE
Sbjct: 272 SLERISDQGQRKTQEQLEVLESLKQELATSQREL-QVLQGSLETSAQ-SEANWAAEFAEL 329
Query: 527 QLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQ 649
+ R S R EEL +++LQ + T ES+ Q
Sbjct: 330 EKERDSLVSGAAHREEELSALRKELQDTQLKLASTEESMCQ 370
>U79734-1|AAC51257.1| 914|Homo sapiens huntingtin interacting
protein 1 protein.
Length = 914
Score = 60.5 bits (140), Expect = 7e-09
Identities = 59/221 (26%), Positives = 101/221 (45%), Gaps = 9/221 (4%)
Frame = +2
Query: 14 RFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLN 193
R V + + +L A+ + R Q + LRA LD L ++ EK Q L+
Sbjct: 277 RVVLQLKGHVSELEADLAEQQHLRQQAADDCEFLRAELDELRRQREDTEKA----QRSLS 332
Query: 194 EVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSL---TTQLED 364
E++ KA + + L +L ++DLLR+ E QVS + +V L +LED
Sbjct: 333 EIERKAQANEQRYSKLKEKYSELVQNHADLLRKNAEVTKQVSMARQAQVDLEREKKELED 392
Query: 365 T-KRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKAN-----AEA 526
+ +R++D+ R+ L +L+ +L + ++ + +G + Q S+AN AE
Sbjct: 393 SLERISDQGQRKTQEQLEVLESLKQELATSQREL-QVLQGSLETSAQ-SEANWAAEFAEL 450
Query: 527 QLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQ 649
+ R S R EEL +++LQ + T ES+ Q
Sbjct: 451 EKERDSLVSGAAHREEELSALRKELQDTQLKLASTEESMCQ 491
>BC139786-1|AAI39787.1| 517|Homo sapiens HIP1 protein protein.
Length = 517
Score = 60.5 bits (140), Expect = 7e-09
Identities = 59/221 (26%), Positives = 101/221 (45%), Gaps = 9/221 (4%)
Frame = +2
Query: 14 RFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLN 193
R V + + +L A+ + R Q + LRA LD L ++ EK Q L+
Sbjct: 102 RVVLQLKGHVSELEADLAEQQHLRQQAADDCEFLRAELDELRRQREDTEKA----QRSLS 157
Query: 194 EVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSL---TTQLED 364
E++ KA + + L +L ++DLLR+ E QVS + +V L +LED
Sbjct: 158 EIERKAQANEQRYSKLKEKYSELVQNHADLLRKNAEVTKQVSMARQAQVDLEREKKELED 217
Query: 365 T-KRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKAN-----AEA 526
+ +R++D+ R+ L +L+ +L + ++ + +G + Q S+AN AE
Sbjct: 218 SLERISDQGQRKTQEQLEVLESLKQELATSQREL-QVLQGSLETSAQ-SEANWAAEFAEL 275
Query: 527 QLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQ 649
+ R S R EEL +++LQ + T ES+ Q
Sbjct: 276 EKERDSLVSGAAHREEELSALRKELQDTQLKLASTEESMCQ 316
>BC110545-1|AAI10546.1| 1037|Homo sapiens huntingtin interacting
protein 1 protein.
Length = 1037
Score = 60.5 bits (140), Expect = 7e-09
Identities = 59/221 (26%), Positives = 101/221 (45%), Gaps = 9/221 (4%)
Frame = +2
Query: 14 RFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLN 193
R V + + +L A+ + R Q + LRA LD L ++ EK Q L+
Sbjct: 400 RVVLQLKGHVSELEADLAEQQHLRQQAADDCEFLRAELDELRRQREDTEKA----QRSLS 455
Query: 194 EVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSL---TTQLED 364
E++ KA + + L +L ++DLLR+ E QVS + +V L +LED
Sbjct: 456 EIERKAQANEQRYSKLKEKYSELVQNHADLLRKNAEVTKQVSMARQAQVDLEREKKELED 515
Query: 365 T-KRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKAN-----AEA 526
+ +R++D+ R+ L +L+ +L + ++ + +G + Q S+AN AE
Sbjct: 516 SLERISDQGQRKTQEQLEVLESLKQELATSQREL-QVLQGSLETSAQ-SEANWAAEFAEL 573
Query: 527 QLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQ 649
+ R S R EEL +++LQ + T ES+ Q
Sbjct: 574 EKERDSLVSGAAHREEELSALRKELQDTQLKLASTEESMCQ 614
>AF365404-1|AAL87037.1| 1030|Homo sapiens huntingtin-interacting
protein 1 protein.
Length = 1030
Score = 60.5 bits (140), Expect = 7e-09
Identities = 59/221 (26%), Positives = 101/221 (45%), Gaps = 9/221 (4%)
Frame = +2
Query: 14 RFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLN 193
R V + + +L A+ + R Q + LRA LD L ++ EK Q L+
Sbjct: 393 RVVLQLKGHVSELEADLAEQQHLRQQAADDCEFLRAELDELRRQREDTEKA----QRSLS 448
Query: 194 EVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSL---TTQLED 364
E++ KA + + L +L ++DLLR+ E QVS + +V L +LED
Sbjct: 449 EIERKAQANEQRYSKLKEKYSELVQNHADLLRKNAEVTKQVSMARQAQVDLEREKKELED 508
Query: 365 T-KRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKAN-----AEA 526
+ +R++D+ R+ L +L+ +L + ++ + +G + Q S+AN AE
Sbjct: 509 SLERISDQGQRKTQEQLEVLESLKQELATSQREL-QVLQGSLETSAQ-SEANWAAEFAEL 566
Query: 527 QLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQ 649
+ R S R EEL +++LQ + T ES+ Q
Sbjct: 567 EKERDSLVSGAAHREEELSALRKELQDTQLKLASTEESMCQ 607
>AF052288-1|AAC33564.1| 995|Homo sapiens huntingtin interacting
protein 1 protein.
Length = 995
Score = 60.5 bits (140), Expect = 7e-09
Identities = 59/221 (26%), Positives = 101/221 (45%), Gaps = 9/221 (4%)
Frame = +2
Query: 14 RFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLN 193
R V + + +L A+ + R Q + LRA LD L ++ EK Q L+
Sbjct: 358 RVVLQLKGHVSELEADLAEQQHLRQQAADDCEFLRAELDELRRQREDTEKA----QRSLS 413
Query: 194 EVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSL---TTQLED 364
E++ KA + + L +L ++DLLR+ E QVS + +V L +LED
Sbjct: 414 EIERKAQANEQRYSKLKEKYSELVQNHADLLRKNAEVTKQVSMARQAQVDLEREKKELED 473
Query: 365 T-KRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKAN-----AEA 526
+ +R++D+ R+ L +L+ +L + ++ + +G + Q S+AN AE
Sbjct: 474 SLERISDQGQRKTQEQLEVLESLKQELATSQREL-QVLQGSLETSAQ-SEANWAAEFAEL 531
Query: 527 QLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQ 649
+ R S R EEL +++LQ + T ES+ Q
Sbjct: 532 EKERDSLVSGAAHREEELSALRKELQDTQLKLASTEESMCQ 572
>X98801-1|CAA67333.1| 1263|Homo sapiens dynactin protein.
Length = 1263
Score = 59.7 bits (138), Expect = 1e-08
Identities = 62/247 (25%), Positives = 114/247 (46%), Gaps = 17/247 (6%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
V D+ E+L+ L +LK +K + + E+ + L+ + K+ ++ LQ +L E
Sbjct: 209 VRDLEEKLETL-RLKRAEDKAKLK---ELEKHKIQLEQVQEWKSKMQEQQADLQRRLKEA 264
Query: 200 QSKADEA----NRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKV---SLTTQL 358
+ +A EA R + ++ + + D E AES ++ +K LTT L
Sbjct: 265 RKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTDL 324
Query: 359 EDTKRLADEEARERATLLGKFRNLEHD-------LDNIREQVEEEAEGKADLQRQLSKAN 517
E K +E+ + A + + LE L +R+ E + LQ+ + K N
Sbjct: 325 EILKAEIEEKGSDGAASSYQLKQLEEQNARLKDALVRMRDLSSSEKQEHVKLQKLMEKKN 384
Query: 518 AEAQLWRSKYE--SEGVARSEE-LEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLA 688
E ++ R + E E ++++E ++E K ++ A L AEE +E L + + LE+ + L
Sbjct: 385 QELEVVRQQRERLQEELSQAESTIDELKEQVDAALG-AEEMVEMLTDRNLNLEEKVRELR 443
Query: 689 TEVEDLQ 709
V DL+
Sbjct: 444 ETVGDLE 450
Score = 50.4 bits (115), Expect = 7e-06
Identities = 41/138 (29%), Positives = 69/138 (50%), Gaps = 6/138 (4%)
Frame = +2
Query: 326 SKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEH---DLDNIREQVEEEAEGKADLQ 496
SK + L Q+ D + + +RA K + LE L+ ++E + E +ADLQ
Sbjct: 199 SKEEEGLRAQVRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQ 258
Query: 497 RQLSKANAEAQLW---RSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALE 667
R+L +A EA+ + +Y E ++ +E A + AEE ESL Q+V AL+
Sbjct: 259 RRLKEARKEAKEALEAKERYMEEMADTADAIEMATLDKEM----AEERAESLQQEVEALK 314
Query: 668 KTKQRLATEVEDLQLEVD 721
+ L T++E L+ E++
Sbjct: 315 ERVDELTTDLEILKAEIE 332
Score = 48.8 bits (111), Expect = 2e-05
Identities = 45/212 (21%), Positives = 94/212 (44%), Gaps = 4/212 (1%)
Frame = +2
Query: 98 SEVNDLRAGLDHLSNEKAAQEKIVKQLQH---QLNEVQSKADEANRTLNDLDAAKKKLSI 268
++V DL L+ L ++A + +K+L+ QL +VQ + DL K+
Sbjct: 207 AQVRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQRRLKEARK 266
Query: 269 ENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDN 448
E + L E +++ + T E + A+ +E L + L DL+
Sbjct: 267 EAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTDLEI 326
Query: 449 IREQVEEEAEGKADLQRQLSKANAE-AQLWRSKYESEGVARSEELEEAKRKLQARLAEAE 625
++ ++EE+ A QL + + A+L + ++ SE+ E KLQ + +
Sbjct: 327 LKAEIEEKGSDGAASSYQLKQLEEQNARLKDALVRMRDLSSSEKQEHV--KLQKLMEKKN 384
Query: 626 ETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
+ +E + Q+ L++ + + +++L+ +VD
Sbjct: 385 QELEVVRQQRERLQEELSQAESTIDELKEQVD 416
Score = 30.7 bits (66), Expect = 6.2
Identities = 24/86 (27%), Positives = 40/86 (46%), Gaps = 8/86 (9%)
Frame = +2
Query: 452 REQVEEEAEGKADLQ-RQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLA---- 616
RE V +E + ++ +LS+AN L K +S E +E+ + +L+ A
Sbjct: 933 RETVIKELKKSLKIKGEELSEANVRLSLLEKKLDSAAKDADERIEKVQTRLEETQALLRK 992
Query: 617 ---EAEETIESLNQKVVALEKTKQRL 685
E EET+++L + LE K L
Sbjct: 993 KEKEFEETMDALQADIDQLEAEKAEL 1018
>BC071583-1|AAH71583.1| 1139|Homo sapiens DCTN1 protein protein.
Length = 1139
Score = 59.7 bits (138), Expect = 1e-08
Identities = 62/247 (25%), Positives = 114/247 (46%), Gaps = 17/247 (6%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
V D+ E+L+ L +LK +K + + E+ + L+ + K+ ++ LQ +L E
Sbjct: 90 VRDLEEKLETL-RLKRAEDKAKLK---ELEKHKIQLEQVQEWKSKMQEQQADLQRRLKEA 145
Query: 200 QSKADEA----NRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKV---SLTTQL 358
+ +A EA R + ++ + + D E AES ++ +K LTT L
Sbjct: 146 RKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTDL 205
Query: 359 EDTKRLADEEARERATLLGKFRNLEHD-------LDNIREQVEEEAEGKADLQRQLSKAN 517
E K +E+ + A + + LE L +R+ E + LQ+ + K N
Sbjct: 206 EILKAEIEEKGSDGAASSYQLKQLEEQNARLKDALVRMRDLSSSEKQEHVKLQKLMEKKN 265
Query: 518 AEAQLWRSKYE--SEGVARSEE-LEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLA 688
E ++ R + E E ++++E ++E K ++ A L AEE +E L + + LE+ + L
Sbjct: 266 QELEVVRQQRERLQEELSQAESTIDELKEQVDAALG-AEEMVEMLTDRNLNLEEKVRELR 324
Query: 689 TEVEDLQ 709
V DL+
Sbjct: 325 ETVGDLE 331
Score = 50.4 bits (115), Expect = 7e-06
Identities = 41/138 (29%), Positives = 69/138 (50%), Gaps = 6/138 (4%)
Frame = +2
Query: 326 SKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEH---DLDNIREQVEEEAEGKADLQ 496
SK + L Q+ D + + +RA K + LE L+ ++E + E +ADLQ
Sbjct: 80 SKEEEGLRAQVRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQ 139
Query: 497 RQLSKANAEAQLW---RSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALE 667
R+L +A EA+ + +Y E ++ +E A + AEE ESL Q+V AL+
Sbjct: 140 RRLKEARKEAKEALEAKERYMEEMADTADAIEMATLDKEM----AEERAESLQQEVEALK 195
Query: 668 KTKQRLATEVEDLQLEVD 721
+ L T++E L+ E++
Sbjct: 196 ERVDELTTDLEILKAEIE 213
Score = 48.8 bits (111), Expect = 2e-05
Identities = 45/212 (21%), Positives = 94/212 (44%), Gaps = 4/212 (1%)
Frame = +2
Query: 98 SEVNDLRAGLDHLSNEKAAQEKIVKQLQH---QLNEVQSKADEANRTLNDLDAAKKKLSI 268
++V DL L+ L ++A + +K+L+ QL +VQ + DL K+
Sbjct: 88 AQVRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQRRLKEARK 147
Query: 269 ENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDN 448
E + L E +++ + T E + A+ +E L + L DL+
Sbjct: 148 EAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTDLEI 207
Query: 449 IREQVEEEAEGKADLQRQLSKANAE-AQLWRSKYESEGVARSEELEEAKRKLQARLAEAE 625
++ ++EE+ A QL + + A+L + ++ SE+ E KLQ + +
Sbjct: 208 LKAEIEEKGSDGAASSYQLKQLEEQNARLKDALVRMRDLSSSEKQEHV--KLQKLMEKKN 265
Query: 626 ETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
+ +E + Q+ L++ + + +++L+ +VD
Sbjct: 266 QELEVVRQQRERLQEELSQAESTIDELKEQVD 297
Score = 30.7 bits (66), Expect = 6.2
Identities = 24/86 (27%), Positives = 40/86 (46%), Gaps = 8/86 (9%)
Frame = +2
Query: 452 REQVEEEAEGKADLQ-RQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLA---- 616
RE V +E + ++ +LS+AN L K +S E +E+ + +L+ A
Sbjct: 814 RETVIKELKKSLKIKGEELSEANVRLSLLEKKLDSAAKDADERIEKVQTRLEETQALLRK 873
Query: 617 ---EAEETIESLNQKVVALEKTKQRL 685
E EET+++L + LE K L
Sbjct: 874 KEKEFEETMDALQADIDQLEAEKAEL 899
>AF086947-1|AAD03694.1| 1261|Homo sapiens dynactin 1 protein.
Length = 1261
Score = 59.7 bits (138), Expect = 1e-08
Identities = 62/247 (25%), Positives = 114/247 (46%), Gaps = 17/247 (6%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
V D+ E+L+ L +LK +K + + E+ + L+ + K+ ++ LQ +L E
Sbjct: 207 VRDLEEKLETL-RLKRAEDKAKLK---ELEKHKIQLEQVQEWKSKMQEQQADLQRRLKEA 262
Query: 200 QSKADEA----NRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKV---SLTTQL 358
+ +A EA R + ++ + + D E AES ++ +K LTT L
Sbjct: 263 RKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTDL 322
Query: 359 EDTKRLADEEARERATLLGKFRNLEHD-------LDNIREQVEEEAEGKADLQRQLSKAN 517
E K +E+ + A + + LE L +R+ E + LQ+ + K N
Sbjct: 323 EILKAEIEEKGSDGAASSYQLKQLEEQNARLKDALVRMRDLSSSEKQEHVKLQKLMEKKN 382
Query: 518 AEAQLWRSKYE--SEGVARSEE-LEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLA 688
E ++ R + E E ++++E ++E K ++ A L AEE +E L + + LE+ + L
Sbjct: 383 QELEVVRQQRERLQEELSQAESTIDELKEQVDAALG-AEEMVEMLTDRNLNLEEKVRELR 441
Query: 689 TEVEDLQ 709
V DL+
Sbjct: 442 ETVGDLE 448
Score = 50.4 bits (115), Expect = 7e-06
Identities = 41/138 (29%), Positives = 69/138 (50%), Gaps = 6/138 (4%)
Frame = +2
Query: 326 SKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEH---DLDNIREQVEEEAEGKADLQ 496
SK + L Q+ D + + +RA K + LE L+ ++E + E +ADLQ
Sbjct: 197 SKEEEGLRAQVRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQ 256
Query: 497 RQLSKANAEAQLW---RSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALE 667
R+L +A EA+ + +Y E ++ +E A + AEE ESL Q+V AL+
Sbjct: 257 RRLKEARKEAKEALEAKERYMEEMADTADAIEMATLDKEM----AEERAESLQQEVEALK 312
Query: 668 KTKQRLATEVEDLQLEVD 721
+ L T++E L+ E++
Sbjct: 313 ERVDELTTDLEILKAEIE 330
Score = 48.8 bits (111), Expect = 2e-05
Identities = 45/212 (21%), Positives = 94/212 (44%), Gaps = 4/212 (1%)
Frame = +2
Query: 98 SEVNDLRAGLDHLSNEKAAQEKIVKQLQH---QLNEVQSKADEANRTLNDLDAAKKKLSI 268
++V DL L+ L ++A + +K+L+ QL +VQ + DL K+
Sbjct: 205 AQVRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQRRLKEARK 264
Query: 269 ENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDN 448
E + L E +++ + T E + A+ +E L + L DL+
Sbjct: 265 EAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTDLEI 324
Query: 449 IREQVEEEAEGKADLQRQLSKANAE-AQLWRSKYESEGVARSEELEEAKRKLQARLAEAE 625
++ ++EE+ A QL + + A+L + ++ SE+ E KLQ + +
Sbjct: 325 LKAEIEEKGSDGAASSYQLKQLEEQNARLKDALVRMRDLSSSEKQEHV--KLQKLMEKKN 382
Query: 626 ETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
+ +E + Q+ L++ + + +++L+ +VD
Sbjct: 383 QELEVVRQQRERLQEELSQAESTIDELKEQVD 414
Score = 30.7 bits (66), Expect = 6.2
Identities = 24/86 (27%), Positives = 40/86 (46%), Gaps = 8/86 (9%)
Frame = +2
Query: 452 REQVEEEAEGKADLQ-RQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLA---- 616
RE V +E + ++ +LS+AN L K +S E +E+ + +L+ A
Sbjct: 931 RETVIKELKKSLKIKGEELSEANVRLSLLEKKLDSAAKDADERIEKVQTRLEETQALLRK 990
Query: 617 ---EAEETIESLNQKVVALEKTKQRL 685
E EET+++L + LE K L
Sbjct: 991 KEKEFEETMDALQADIDQLEAEKAEL 1016
>AF064205-2|AAD55812.1| 1144|Homo sapiens dynactin 1 p135 isoform
protein.
Length = 1144
Score = 59.7 bits (138), Expect = 1e-08
Identities = 62/247 (25%), Positives = 114/247 (46%), Gaps = 17/247 (6%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
V D+ E+L+ L +LK +K + + E+ + L+ + K+ ++ LQ +L E
Sbjct: 90 VRDLEEKLETL-RLKRAEDKAKLK---ELEKHKIQLEQVQEWKSKMQEQQADLQRRLKEA 145
Query: 200 QSKADEA----NRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKV---SLTTQL 358
+ +A EA R + ++ + + D E AES ++ +K LTT L
Sbjct: 146 RKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTDL 205
Query: 359 EDTKRLADEEARERATLLGKFRNLEHD-------LDNIREQVEEEAEGKADLQRQLSKAN 517
E K +E+ + A + + LE L +R+ E + LQ+ + K N
Sbjct: 206 EILKAEIEEKGSDGAASSYQLKQLEEQNARLKDALVRMRDLSSSEKQEHVKLQKLMEKKN 265
Query: 518 AEAQLWRSKYE--SEGVARSEE-LEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLA 688
E ++ R + E E ++++E ++E K ++ A L AEE +E L + + LE+ + L
Sbjct: 266 QELEVVRQQRERLQEELSQAESTIDELKEQVDAALG-AEEMVEMLTDRNLNLEEKVRELR 324
Query: 689 TEVEDLQ 709
V DL+
Sbjct: 325 ETVGDLE 331
Score = 50.4 bits (115), Expect = 7e-06
Identities = 41/138 (29%), Positives = 69/138 (50%), Gaps = 6/138 (4%)
Frame = +2
Query: 326 SKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEH---DLDNIREQVEEEAEGKADLQ 496
SK + L Q+ D + + +RA K + LE L+ ++E + E +ADLQ
Sbjct: 80 SKEEEGLRAQVRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQ 139
Query: 497 RQLSKANAEAQLW---RSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALE 667
R+L +A EA+ + +Y E ++ +E A + AEE ESL Q+V AL+
Sbjct: 140 RRLKEARKEAKEALEAKERYMEEMADTADAIEMATLDKEM----AEERAESLQQEVEALK 195
Query: 668 KTKQRLATEVEDLQLEVD 721
+ L T++E L+ E++
Sbjct: 196 ERVDELTTDLEILKAEIE 213
Score = 48.8 bits (111), Expect = 2e-05
Identities = 45/212 (21%), Positives = 94/212 (44%), Gaps = 4/212 (1%)
Frame = +2
Query: 98 SEVNDLRAGLDHLSNEKAAQEKIVKQLQH---QLNEVQSKADEANRTLNDLDAAKKKLSI 268
++V DL L+ L ++A + +K+L+ QL +VQ + DL K+
Sbjct: 88 AQVRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQRRLKEARK 147
Query: 269 ENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDN 448
E + L E +++ + T E + A+ +E L + L DL+
Sbjct: 148 EAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTDLEI 207
Query: 449 IREQVEEEAEGKADLQRQLSKANAE-AQLWRSKYESEGVARSEELEEAKRKLQARLAEAE 625
++ ++EE+ A QL + + A+L + ++ SE+ E KLQ + +
Sbjct: 208 LKAEIEEKGSDGAASSYQLKQLEEQNARLKDALVRMRDLSSSEKQEHV--KLQKLMEKKN 265
Query: 626 ETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
+ +E + Q+ L++ + + +++L+ +VD
Sbjct: 266 QELEVVRQQRERLQEELSQAESTIDELKEQVD 297
Score = 30.7 bits (66), Expect = 6.2
Identities = 24/86 (27%), Positives = 40/86 (46%), Gaps = 8/86 (9%)
Frame = +2
Query: 452 REQVEEEAEGKADLQ-RQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLA---- 616
RE V +E + ++ +LS+AN L K +S E +E+ + +L+ A
Sbjct: 814 RETVIKELKKSLKIKGEELSEANVRLSLLEKKLDSAAKDADERIEKVQTRLEETQALLRK 873
Query: 617 ---EAEETIESLNQKVVALEKTKQRL 685
E EET+++L + LE K L
Sbjct: 874 KEKEFEETMDALQADIDQLEAEKAEL 899
>AF064205-1|AAD55811.1| 1278|Homo sapiens dynactin 1 p150 isoform
protein.
Length = 1278
Score = 59.7 bits (138), Expect = 1e-08
Identities = 62/247 (25%), Positives = 114/247 (46%), Gaps = 17/247 (6%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
V D+ E+L+ L +LK +K + + E+ + L+ + K+ ++ LQ +L E
Sbjct: 224 VRDLEEKLETL-RLKRAEDKAKLK---ELEKHKIQLEQVQEWKSKMQEQQADLQRRLKEA 279
Query: 200 QSKADEA----NRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKV---SLTTQL 358
+ +A EA R + ++ + + D E AES ++ +K LTT L
Sbjct: 280 RKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTDL 339
Query: 359 EDTKRLADEEARERATLLGKFRNLEHD-------LDNIREQVEEEAEGKADLQRQLSKAN 517
E K +E+ + A + + LE L +R+ E + LQ+ + K N
Sbjct: 340 EILKAEIEEKGSDGAASSYQLKQLEEQNARLKDALVRMRDLSSSEKQEHVKLQKLMEKKN 399
Query: 518 AEAQLWRSKYE--SEGVARSEE-LEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLA 688
E ++ R + E E ++++E ++E K ++ A L AEE +E L + + LE+ + L
Sbjct: 400 QELEVVRQQRERLQEELSQAESTIDELKEQVDAALG-AEEMVEMLTDRNLNLEEKVRELR 458
Query: 689 TEVEDLQ 709
V DL+
Sbjct: 459 ETVGDLE 465
Score = 50.4 bits (115), Expect = 7e-06
Identities = 41/138 (29%), Positives = 69/138 (50%), Gaps = 6/138 (4%)
Frame = +2
Query: 326 SKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEH---DLDNIREQVEEEAEGKADLQ 496
SK + L Q+ D + + +RA K + LE L+ ++E + E +ADLQ
Sbjct: 214 SKEEEGLRAQVRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQ 273
Query: 497 RQLSKANAEAQLW---RSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALE 667
R+L +A EA+ + +Y E ++ +E A + AEE ESL Q+V AL+
Sbjct: 274 RRLKEARKEAKEALEAKERYMEEMADTADAIEMATLDKEM----AEERAESLQQEVEALK 329
Query: 668 KTKQRLATEVEDLQLEVD 721
+ L T++E L+ E++
Sbjct: 330 ERVDELTTDLEILKAEIE 347
Score = 48.8 bits (111), Expect = 2e-05
Identities = 45/212 (21%), Positives = 94/212 (44%), Gaps = 4/212 (1%)
Frame = +2
Query: 98 SEVNDLRAGLDHLSNEKAAQEKIVKQLQH---QLNEVQSKADEANRTLNDLDAAKKKLSI 268
++V DL L+ L ++A + +K+L+ QL +VQ + DL K+
Sbjct: 222 AQVRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQRRLKEARK 281
Query: 269 ENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDN 448
E + L E +++ + T E + A+ +E L + L DL+
Sbjct: 282 EAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTDLEI 341
Query: 449 IREQVEEEAEGKADLQRQLSKANAE-AQLWRSKYESEGVARSEELEEAKRKLQARLAEAE 625
++ ++EE+ A QL + + A+L + ++ SE+ E KLQ + +
Sbjct: 342 LKAEIEEKGSDGAASSYQLKQLEEQNARLKDALVRMRDLSSSEKQEHV--KLQKLMEKKN 399
Query: 626 ETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
+ +E + Q+ L++ + + +++L+ +VD
Sbjct: 400 QELEVVRQQRERLQEELSQAESTIDELKEQVD 431
Score = 30.7 bits (66), Expect = 6.2
Identities = 24/86 (27%), Positives = 40/86 (46%), Gaps = 8/86 (9%)
Frame = +2
Query: 452 REQVEEEAEGKADLQ-RQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLA---- 616
RE V +E + ++ +LS+AN L K +S E +E+ + +L+ A
Sbjct: 948 RETVIKELKKSLKIKGEELSEANVRLSLLEKKLDSAAKDADERIEKVQTRLEETQALLRK 1007
Query: 617 ---EAEETIESLNQKVVALEKTKQRL 685
E EET+++L + LE K L
Sbjct: 1008 KEKEFEETMDALQADIDQLEAEKAEL 1033
>AB209625-1|BAD92862.1| 459|Homo sapiens dynactin 1 isoform 1
variant protein.
Length = 459
Score = 59.7 bits (138), Expect = 1e-08
Identities = 62/247 (25%), Positives = 114/247 (46%), Gaps = 17/247 (6%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
V D+ E+L+ L +LK +K + + E+ + L+ + K+ ++ LQ +L E
Sbjct: 49 VRDLEEKLETL-RLKRAEDKAKLK---ELEKHKIQLEQVQEWKSKMQEQQADLQRRLKEA 104
Query: 200 QSKADEA----NRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKV---SLTTQL 358
+ +A EA R + ++ + + D E AES ++ +K LTT L
Sbjct: 105 RKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTDL 164
Query: 359 EDTKRLADEEARERATLLGKFRNLEHD-------LDNIREQVEEEAEGKADLQRQLSKAN 517
E K +E+ + A + + LE L +R+ E + LQ+ + K N
Sbjct: 165 EILKAEIEEKGSDGAASSYQLKQLEEQNARLKDALVRMRDLSSSEKQEHVKLQKLMEKKN 224
Query: 518 AEAQLWRSKYE--SEGVARSEE-LEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLA 688
E ++ R + E E ++++E ++E K ++ A L AEE +E L + + LE+ + L
Sbjct: 225 QELEVVRQQRERLQEELSQAESTIDELKEQVDAALG-AEEMVEMLTDRNLNLEEKVRELR 283
Query: 689 TEVEDLQ 709
V DL+
Sbjct: 284 ETVGDLE 290
Score = 48.8 bits (111), Expect = 2e-05
Identities = 45/212 (21%), Positives = 94/212 (44%), Gaps = 4/212 (1%)
Frame = +2
Query: 98 SEVNDLRAGLDHLSNEKAAQEKIVKQLQH---QLNEVQSKADEANRTLNDLDAAKKKLSI 268
++V DL L+ L ++A + +K+L+ QL +VQ + DL K+
Sbjct: 47 AQVRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQRRLKEARK 106
Query: 269 ENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDN 448
E + L E +++ + T E + A+ +E L + L DL+
Sbjct: 107 EAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTDLEI 166
Query: 449 IREQVEEEAEGKADLQRQLSKANAE-AQLWRSKYESEGVARSEELEEAKRKLQARLAEAE 625
++ ++EE+ A QL + + A+L + ++ SE+ E KLQ + +
Sbjct: 167 LKAEIEEKGSDGAASSYQLKQLEEQNARLKDALVRMRDLSSSEKQEHV--KLQKLMEKKN 224
Query: 626 ETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
+ +E + Q+ L++ + + +++L+ +VD
Sbjct: 225 QELEVVRQQRERLQEELSQAESTIDELKEQVD 256
Score = 48.4 bits (110), Expect = 3e-05
Identities = 39/132 (29%), Positives = 66/132 (50%), Gaps = 6/132 (4%)
Frame = +2
Query: 344 LTTQLEDTKRLADEEARERATLLGKFRNLEH---DLDNIREQVEEEAEGKADLQRQLSKA 514
L Q+ D + + +RA K + LE L+ ++E + E +ADLQR+L +A
Sbjct: 45 LRAQVRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQRRLKEA 104
Query: 515 NAEAQLW---RSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRL 685
EA+ + +Y E ++ +E A + AEE ESL Q+V AL++ L
Sbjct: 105 RKEAKEALEAKERYMEEMADTADAIEMATLDKEM----AEERAESLQQEVEALKERVDEL 160
Query: 686 ATEVEDLQLEVD 721
T++E L+ E++
Sbjct: 161 TTDLEILKAEIE 172
>D87931-1|BAA75636.1| 1388|Homo sapiens Rho kinase protein.
Length = 1388
Score = 59.3 bits (137), Expect = 2e-08
Identities = 52/222 (23%), Positives = 106/222 (47%), Gaps = 14/222 (6%)
Frame = +2
Query: 101 EVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSD 280
+V +L ++ + ++ + +K Q+N ++ + + N L K L +N++
Sbjct: 788 DVRNLTLKIEQETQKRCLTQNDLKMQTQQVNTLKMSEKQLKQENNHLMEMKMNLEKQNAE 847
Query: 281 LLRQLEEAESQVSQLSK-------IKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHD 439
L ++ ++A+ Q+ +L TQ+ + K +E+ + L K + L+ +
Sbjct: 848 LRKERQDADGQMKELQDQLEAEQYFSTLYKTQVRELKEECEEKTKLGKELQQKKQELQDE 907
Query: 440 LDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEE--AKRKLQ--- 604
D++ Q+E KAD + QL+++ AE Q S E E + + E++E A+ K +
Sbjct: 908 RDSLAAQLEITLT-KADSE-QLARSIAEEQY--SDLEKEKIMKELEIKEMMARHKQELTE 963
Query: 605 --ARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
A +A EET +L V L K+ L +++D+Q ++ R
Sbjct: 964 KDATIASLEETNRTLTSDVANLANEKEELNNKLKDVQEQLSR 1005
Score = 51.6 bits (118), Expect = 3e-06
Identities = 62/206 (30%), Positives = 95/206 (46%), Gaps = 7/206 (3%)
Frame = +2
Query: 128 DHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAE 307
+HLSNE A+E E++ K N L K +E LR + E
Sbjct: 454 EHLSNEMQAKE-----------ELEQKCKSVNTRLE-----KTAKELEEEITLR--KSVE 495
Query: 308 SQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKA 487
S + QL + K L + + +R AD EA K RNLE+D++++++Q+E+ +
Sbjct: 496 SALRQLEREKALLQHKNAEYQRKADHEA-------DKKRNLENDVNSLKDQLEDLKKRNQ 548
Query: 488 DLQRQLSKANAEAQLWRSKYESEGVARSEELEEAK-RKLQARLAEAEETIES----LNQK 652
+ Q K N QL R E+ + R+E A+ RK QA ++ + +ES L K
Sbjct: 549 NSQISTEKVN---QLQRQLDETNALLRTESDTAARLRKTQAESSKQIQQLESNNRDLQDK 605
Query: 653 VVALEKTKQRLATEVEDLQ--LEVDR 724
LE K +L E +LQ LE +R
Sbjct: 606 NCLLETAKLKLEKEFINLQSALESER 631
Score = 50.4 bits (115), Expect = 7e-06
Identities = 54/243 (22%), Positives = 101/243 (41%), Gaps = 21/243 (8%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD 214
++ + L ++K EK A+ E D + L ++ A++ + Q+ E++ + +
Sbjct: 829 QENNHLMEMKMNLEKQNAELRKERQDADGQMKELQDQLEAEQYFSTLYKTQVRELKEECE 888
Query: 215 EANRTLNDLDAAKKKLSIENSDLLRQLEE--------------AESQVSQLSKIKVSLTT 352
E + +L K++L E L QLE AE Q S L K K+
Sbjct: 889 EKTKLGKELQQKKQELQDERDSLAAQLEITLTKADSEQLARSIAEEQYSDLEKEKIMKEL 948
Query: 353 QLEDTKRLADEEARER----ATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANA 520
++++ +E E+ A+L R L D+ N+ + EE D+Q QLS+
Sbjct: 949 EIKEMMARHKQELTEKDATIASLEETNRTLTSDVANLANEKEELNNKLKDVQEQLSRLKD 1008
Query: 521 E---AQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLAT 691
E A ++++E + + +A KL + E + V EK ++L
Sbjct: 1009 EEISAAAIKAQFEKQLLTERTLKTQAVNKLAEIMNRKEPVKRGNDTDVRRKEKENRKLHM 1068
Query: 692 EVE 700
E++
Sbjct: 1069 ELK 1071
Score = 43.2 bits (97), Expect = 0.001
Identities = 60/233 (25%), Positives = 100/233 (42%), Gaps = 6/233 (2%)
Frame = +2
Query: 35 EQLDQLNK-LKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKA 211
E+L+Q K + + EK + E+ LR ++ + ++ + LQH+ E Q KA
Sbjct: 464 EELEQKCKSVNTRLEKTAKELEEEIT-LRKSVESALRQLEREKAL---LQHKNAEYQRKA 519
Query: 212 DEANRTLNDLDAAKKKLSIEN--SDLLRQLEEAE--SQVSQLSKIKVS-LTTQLEDTKRL 376
D A KK ++EN + L QLE+ + +Q SQ+S KV+ L QL++T L
Sbjct: 520 DH---------EADKKRNLENDVNSLKDQLEDLKKRNQNSQISTEKVNQLQRQLDETNAL 570
Query: 377 ADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESE 556
E+ A L + + + + L+ K E +S ESE
Sbjct: 571 LRTESDTAARLRKTQAESSKQIQQLESNNRDLQDKNCLLETAKLKLEKEFINLQSALESE 630
Query: 557 GVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLE 715
R+ E LQ R+ EE +++ + +E K++L DL+ E
Sbjct: 631 RRDRTHG-SEIINDLQGRICGLEEDLKNGKILLAKVELEKRQLQERFTDLEKE 682
>BC111801-1|AAI11802.1| 703|Homo sapiens ROCK2 protein protein.
Length = 703
Score = 59.3 bits (137), Expect = 2e-08
Identities = 52/222 (23%), Positives = 106/222 (47%), Gaps = 14/222 (6%)
Frame = +2
Query: 101 EVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSD 280
+V +L ++ + ++ + +K Q+N ++ + + N L K L +N++
Sbjct: 103 DVRNLTLKIEQETQKRCLTQNDLKMQTQQVNTLKMSEKQLKQENNHLMEMKMNLEKQNAE 162
Query: 281 LLRQLEEAESQVSQLSK-------IKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHD 439
L ++ ++A+ Q+ +L TQ+ + K +E+ + L K + L+ +
Sbjct: 163 LRKERQDADGQMKELQDQLEAEQYFSTLYKTQVRELKEECEEKTKLGKELQQKKQELQDE 222
Query: 440 LDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEE--AKRKLQ--- 604
D++ Q+E KAD + QL+++ AE Q S E E + + E++E A+ K +
Sbjct: 223 RDSLAAQLEITLT-KADSE-QLARSIAEEQY--SDLEKEKIMKELEIKEMMARHKQELTE 278
Query: 605 --ARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
A +A EET +L V L K+ L +++D+Q ++ R
Sbjct: 279 KDATIASLEETNRTLTSDVANLANEKEELNNKLKDVQEQLSR 320
Score = 50.4 bits (115), Expect = 7e-06
Identities = 54/243 (22%), Positives = 101/243 (41%), Gaps = 21/243 (8%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD 214
++ + L ++K EK A+ E D + L ++ A++ + Q+ E++ + +
Sbjct: 144 QENNHLMEMKMNLEKQNAELRKERQDADGQMKELQDQLEAEQYFSTLYKTQVRELKEECE 203
Query: 215 EANRTLNDLDAAKKKLSIENSDLLRQLEE--------------AESQVSQLSKIKVSLTT 352
E + +L K++L E L QLE AE Q S L K K+
Sbjct: 204 EKTKLGKELQQKKQELQDERDSLAAQLEITLTKADSEQLARSIAEEQYSDLEKEKIMKEL 263
Query: 353 QLEDTKRLADEEARER----ATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANA 520
++++ +E E+ A+L R L D+ N+ + EE D+Q QLS+
Sbjct: 264 EIKEMMARHKQELTEKDATIASLEETNRTLTSDVANLANEKEELNNKLKDVQEQLSRLKD 323
Query: 521 E---AQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLAT 691
E A ++++E + + +A KL + E + V EK ++L
Sbjct: 324 EEISAAAIKAQFEKQLLTERTLKTQAVNKLAEIMNRKEPVKRGNDTDVRRKEKENRKLHM 383
Query: 692 EVE 700
E++
Sbjct: 384 ELK 386
>AC018463-2|AAX93049.1| 1337|Homo sapiens unknown protein.
Length = 1337
Score = 59.3 bits (137), Expect = 2e-08
Identities = 52/222 (23%), Positives = 106/222 (47%), Gaps = 14/222 (6%)
Frame = +2
Query: 101 EVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSD 280
+V +L ++ + ++ + +K Q+N ++ + + N L K L +N++
Sbjct: 737 DVRNLTLKIEQETQKRCLTQNDLKMQTQQVNTLKMSEKQLKQENNHLMEMKMNLEKQNAE 796
Query: 281 LLRQLEEAESQVSQLSK-------IKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHD 439
L ++ ++A+ Q+ +L TQ+ + K +E+ + L K + L+ +
Sbjct: 797 LRKERQDADGQMKELQDQLEAEQYFSTLYKTQVRELKEECEEKTKLGKELQQKKQELQDE 856
Query: 440 LDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEE--AKRKLQ--- 604
D++ Q+E KAD + QL+++ AE Q S E E + + E++E A+ K +
Sbjct: 857 RDSLAAQLEITLT-KADSE-QLARSIAEEQY--SDLEKEKIMKELEIKEMMARHKQELTE 912
Query: 605 --ARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
A +A EET +L V L K+ L +++D+Q ++ R
Sbjct: 913 KDATIASLEETNRTLTSDVANLANEKEELNNKLKDVQEQLSR 954
Score = 51.6 bits (118), Expect = 3e-06
Identities = 62/206 (30%), Positives = 95/206 (46%), Gaps = 7/206 (3%)
Frame = +2
Query: 128 DHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAE 307
+HLSNE A+E E++ K N L K +E LR + E
Sbjct: 403 EHLSNEMQAKE-----------ELEQKCKSVNTRLE-----KTAKELEEEITLR--KSVE 444
Query: 308 SQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKA 487
S + QL + K L + + +R AD EA K RNLE+D++++++Q+E+ +
Sbjct: 445 SALRQLEREKALLQHKNAEYQRKADHEA-------DKKRNLENDVNSLKDQLEDLKKRNQ 497
Query: 488 DLQRQLSKANAEAQLWRSKYESEGVARSEELEEAK-RKLQARLAEAEETIES----LNQK 652
+ Q K N QL R E+ + R+E A+ RK QA ++ + +ES L K
Sbjct: 498 NSQISTEKVN---QLQRQLDETNALLRTESDTAARLRKTQAESSKQIQQLESNNRDLQDK 554
Query: 653 VVALEKTKQRLATEVEDLQ--LEVDR 724
LE K +L E +LQ LE +R
Sbjct: 555 NCLLETAKLKLEKEFINLQSALESER 580
Score = 50.4 bits (115), Expect = 7e-06
Identities = 54/243 (22%), Positives = 101/243 (41%), Gaps = 21/243 (8%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD 214
++ + L ++K EK A+ E D + L ++ A++ + Q+ E++ + +
Sbjct: 778 QENNHLMEMKMNLEKQNAELRKERQDADGQMKELQDQLEAEQYFSTLYKTQVRELKEECE 837
Query: 215 EANRTLNDLDAAKKKLSIENSDLLRQLEE--------------AESQVSQLSKIKVSLTT 352
E + +L K++L E L QLE AE Q S L K K+
Sbjct: 838 EKTKLGKELQQKKQELQDERDSLAAQLEITLTKADSEQLARSIAEEQYSDLEKEKIMKEL 897
Query: 353 QLEDTKRLADEEARER----ATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANA 520
++++ +E E+ A+L R L D+ N+ + EE D+Q QLS+
Sbjct: 898 EIKEMMARHKQELTEKDATIASLEETNRTLTSDVANLANEKEELNNKLKDVQEQLSRLKD 957
Query: 521 E---AQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLAT 691
E A ++++E + + +A KL + E + V EK ++L
Sbjct: 958 EEISAAAIKAQFEKQLLTERTLKTQAVNKLAEIMNRKEPVKRGNDTDVRRKEKENRKLHM 1017
Query: 692 EVE 700
E++
Sbjct: 1018 ELK 1020
Score = 43.2 bits (97), Expect = 0.001
Identities = 60/233 (25%), Positives = 100/233 (42%), Gaps = 6/233 (2%)
Frame = +2
Query: 35 EQLDQLNK-LKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKA 211
E+L+Q K + + EK + E+ LR ++ + ++ + LQH+ E Q KA
Sbjct: 413 EELEQKCKSVNTRLEKTAKELEEEIT-LRKSVESALRQLEREKAL---LQHKNAEYQRKA 468
Query: 212 DEANRTLNDLDAAKKKLSIEN--SDLLRQLEEAE--SQVSQLSKIKVS-LTTQLEDTKRL 376
D A KK ++EN + L QLE+ + +Q SQ+S KV+ L QL++T L
Sbjct: 469 DH---------EADKKRNLENDVNSLKDQLEDLKKRNQNSQISTEKVNQLQRQLDETNAL 519
Query: 377 ADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESE 556
E+ A L + + + + L+ K E +S ESE
Sbjct: 520 LRTESDTAARLRKTQAESSKQIQQLESNNRDLQDKNCLLETAKLKLEKEFINLQSALESE 579
Query: 557 GVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLE 715
R+ E LQ R+ EE +++ + +E K++L DL+ E
Sbjct: 580 RRDRTHG-SEIINDLQGRICGLEEDLKNGKILLAKVELEKRQLQERFTDLEKE 631
>AB014519-1|BAA31594.2| 1428|Homo sapiens KIAA0619 protein protein.
Length = 1428
Score = 59.3 bits (137), Expect = 2e-08
Identities = 52/222 (23%), Positives = 106/222 (47%), Gaps = 14/222 (6%)
Frame = +2
Query: 101 EVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSD 280
+V +L ++ + ++ + +K Q+N ++ + + N L K L +N++
Sbjct: 828 DVRNLTLKIEQETQKRCLTQNDLKMQTQQVNTLKMSEKQLKQENNHLMEMKMNLEKQNAE 887
Query: 281 LLRQLEEAESQVSQLSK-------IKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHD 439
L ++ ++A+ Q+ +L TQ+ + K +E+ + L K + L+ +
Sbjct: 888 LRKERQDADGQMKELQDQLEAEQYFSTLYKTQVRELKEECEEKTKLGKELQQKKQELQDE 947
Query: 440 LDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEE--AKRKLQ--- 604
D++ Q+E KAD + QL+++ AE Q S E E + + E++E A+ K +
Sbjct: 948 RDSLAAQLEITLT-KADSE-QLARSIAEEQY--SDLEKEKIMKELEIKEMMARHKQELTE 1003
Query: 605 --ARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
A +A EET +L V L K+ L +++D+Q ++ R
Sbjct: 1004 KDATIASLEETNRTLTSDVANLANEKEELNNKLKDVQEQLSR 1045
Score = 51.6 bits (118), Expect = 3e-06
Identities = 62/206 (30%), Positives = 95/206 (46%), Gaps = 7/206 (3%)
Frame = +2
Query: 128 DHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAE 307
+HLSNE A+E E++ K N L K +E LR + E
Sbjct: 494 EHLSNEMQAKE-----------ELEQKCKSVNTRLE-----KTAKELEEEITLR--KSVE 535
Query: 308 SQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKA 487
S + QL + K L + + +R AD EA K RNLE+D++++++Q+E+ +
Sbjct: 536 SALRQLEREKALLQHKNAEYQRKADHEA-------DKKRNLENDVNSLKDQLEDLKKRNQ 588
Query: 488 DLQRQLSKANAEAQLWRSKYESEGVARSEELEEAK-RKLQARLAEAEETIES----LNQK 652
+ Q K N QL R E+ + R+E A+ RK QA ++ + +ES L K
Sbjct: 589 NSQISTEKVN---QLQRQLDETNALLRTESDTAARLRKTQAESSKQIQQLESNNRDLQDK 645
Query: 653 VVALEKTKQRLATEVEDLQ--LEVDR 724
LE K +L E +LQ LE +R
Sbjct: 646 NCLLETAKLKLEKEFINLQSALESER 671
Score = 50.4 bits (115), Expect = 7e-06
Identities = 54/243 (22%), Positives = 101/243 (41%), Gaps = 21/243 (8%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD 214
++ + L ++K EK A+ E D + L ++ A++ + Q+ E++ + +
Sbjct: 869 QENNHLMEMKMNLEKQNAELRKERQDADGQMKELQDQLEAEQYFSTLYKTQVRELKEECE 928
Query: 215 EANRTLNDLDAAKKKLSIENSDLLRQLEE--------------AESQVSQLSKIKVSLTT 352
E + +L K++L E L QLE AE Q S L K K+
Sbjct: 929 EKTKLGKELQQKKQELQDERDSLAAQLEITLTKADSEQLARSIAEEQYSDLEKEKIMKEL 988
Query: 353 QLEDTKRLADEEARER----ATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANA 520
++++ +E E+ A+L R L D+ N+ + EE D+Q QLS+
Sbjct: 989 EIKEMMARHKQELTEKDATIASLEETNRTLTSDVANLANEKEELNNKLKDVQEQLSRLKD 1048
Query: 521 E---AQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLAT 691
E A ++++E + + +A KL + E + V EK ++L
Sbjct: 1049 EEISAAAIKAQFEKQLLTERTLKTQAVNKLAEIMNRKEPVKRGNDTDVRRKEKENRKLHM 1108
Query: 692 EVE 700
E++
Sbjct: 1109 ELK 1111
Score = 43.2 bits (97), Expect = 0.001
Identities = 60/233 (25%), Positives = 100/233 (42%), Gaps = 6/233 (2%)
Frame = +2
Query: 35 EQLDQLNK-LKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKA 211
E+L+Q K + + EK + E+ LR ++ + ++ + LQH+ E Q KA
Sbjct: 504 EELEQKCKSVNTRLEKTAKELEEEIT-LRKSVESALRQLEREKAL---LQHKNAEYQRKA 559
Query: 212 DEANRTLNDLDAAKKKLSIEN--SDLLRQLEEAE--SQVSQLSKIKVS-LTTQLEDTKRL 376
D A KK ++EN + L QLE+ + +Q SQ+S KV+ L QL++T L
Sbjct: 560 DH---------EADKKRNLENDVNSLKDQLEDLKKRNQNSQISTEKVNQLQRQLDETNAL 610
Query: 377 ADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESE 556
E+ A L + + + + L+ K E +S ESE
Sbjct: 611 LRTESDTAARLRKTQAESSKQIQQLESNNRDLQDKNCLLETAKLKLEKEFINLQSALESE 670
Query: 557 GVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLE 715
R+ E LQ R+ EE +++ + +E K++L DL+ E
Sbjct: 671 RRDRTHG-SEIINDLQGRICGLEEDLKNGKILLAKVELEKRQLQERFTDLEKE 722
>U90236-1|AAC51654.2| 1262|Homo sapiens myosin VI protein.
Length = 1262
Score = 58.8 bits (136), Expect = 2e-08
Identities = 47/188 (25%), Positives = 89/188 (47%), Gaps = 1/188 (0%)
Frame = +2
Query: 134 LSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQ 313
L + K K +K L+ ++ + +K T + L + +LL L++ + Q
Sbjct: 860 LKDGKPEMNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYDALVKSSEELLSALQKKKQQ 919
Query: 314 VSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADL 493
+ +++ ++ KR ++E R R + R ++ +++ R+Q EEE + + D
Sbjct: 920 EEEAERLRRIQEEMEKERKRREEDEKRRRKE--EEERRMKLEMEAKRKQEEEERKKREDD 977
Query: 494 QRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAE-ETIESLNQKVVALEK 670
++++ +A EAQL R K E E E R+L R+A++E E I Q +AL +
Sbjct: 978 EKRI-QAEVEAQLARQKEEESQQQAVLEQERRDRELALRIAQSEAELISDEAQADLALRR 1036
Query: 671 TKQRLATE 694
LAT+
Sbjct: 1037 GPAVLATK 1044
>BC007877-1|AAH07877.2| 256|Homo sapiens MYH14 protein protein.
Length = 256
Score = 58.8 bits (136), Expect = 2e-08
Identities = 49/190 (25%), Positives = 92/190 (48%), Gaps = 5/190 (2%)
Frame = +2
Query: 128 DHLSNEKAAQEKIVKQLQHQLNEVQSKADE--ANRTLN-DLDAAKKKLSIENSDLLRQLE 298
+ L E++ E + + + L +V+S E A R+ + ++ +++L + +L +L
Sbjct: 21 EELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLG 80
Query: 299 EAESQVSQLSKIKVS-LTTQLEDTKRLADEEARERATLLGKF-RNLEHDLDNIREQVEEE 472
E ++ K+ ++ L ++L + ++E RER L GK R E L + QVEEE
Sbjct: 81 EEDAGARARHKMTIAALESKLAQAEEQLEQETRERI-LSGKLVRRAEKRLKEVVLQVEEE 139
Query: 473 AEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQK 652
L+ QL K N + + + E E + + +R+LQ L + E+ ES+N++
Sbjct: 140 RRVADQLRDQLEKGNLRVKQLKRQLE-EAEEEASRAQAGRRRLQRELEDVTESAESMNRE 198
Query: 653 VVALEKTKQR 682
V L +R
Sbjct: 199 VTTLRNRLRR 208
Score = 51.2 bits (117), Expect = 4e-06
Identities = 33/121 (27%), Positives = 58/121 (47%)
Frame = +2
Query: 62 KAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDL 241
+A+ + A S++ L+ + E+ K+V++ + +L EV + +E R + L
Sbjct: 87 RARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQL 146
Query: 242 DAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKF 421
+K ++ L RQLEEAE + S+ + L +LED A+ RE TL +
Sbjct: 147 RDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRL 206
Query: 422 R 424
R
Sbjct: 207 R 207
Score = 47.2 bits (107), Expect = 7e-05
Identities = 41/195 (21%), Positives = 80/195 (41%), Gaps = 4/195 (2%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGL-DHLSNEKAAQEKIVKQLQHQLNE 196
V + +L AKAE R Q ++ +LR L + + +A + + L+ +L +
Sbjct: 44 VESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQ 103
Query: 197 VQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRL 376
+ + ++ R ++ +++ Q+EE QL +++ KR
Sbjct: 104 AEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQ 163
Query: 377 ADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKA--NAEAQLWRSKYE 550
+E E + R L+ +L+++ E E L+ +L + + R +
Sbjct: 164 LEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFR 223
Query: 551 -SEGVARSEELEEAK 592
EGVA EE EEA+
Sbjct: 224 LEEGVASDEEAEEAQ 238
>AY610514-1|AAT37906.1| 1302|Homo sapiens paracingulin protein.
Length = 1302
Score = 58.8 bits (136), Expect = 2e-08
Identities = 57/198 (28%), Positives = 86/198 (43%), Gaps = 9/198 (4%)
Frame = +2
Query: 158 EKIVKQLQHQLNEVQSKADEANRT--LNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSK 331
EKI Q N T + DL K KL+IE ++L RQL+ + +
Sbjct: 583 EKIQTLKSRAAGSAQGNNQACNSTSEVKDLLEQKSKLTIEVAELQRQLQLEVKNQQNIKE 642
Query: 332 IKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDL-DNIRE--QVEEEAEGKA----D 490
+ + LE+ + +E+ E +TL + E +L N+ E QV+ E E D
Sbjct: 643 ERERMRANLEELRSQHNEKVEENSTLQQRLEESEGELRKNLEELFQVKMEREQHQTEIRD 702
Query: 491 LQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEK 670
LQ QLS+ + E + + E A EEL +AK+ LQ L E + L ++ L
Sbjct: 703 LQDQLSEMHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIAKEGREDLLRKRERELTA 762
Query: 671 TKQRLATEVEDLQLEVDR 724
K L EV E+D+
Sbjct: 763 LKGALKEEVSSHDQEMDK 780
Score = 58.4 bits (135), Expect = 3e-08
Identities = 49/218 (22%), Positives = 98/218 (44%), Gaps = 1/218 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+ D+ +L+ + LK + Q ++V+ L L+ N + + + + Q+ ++
Sbjct: 1042 LKDLEYELEAKSHLKDDRSRLVKQMEAKVSQLEMELEEERNNSDLLSERISRSREQMEQL 1101
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAE-SQVSQLSKIKVSLTTQLEDTKRL 376
++ + DL+ K L +N DL ++ E S S + V + ++ + +
Sbjct: 1102 RNGLLQERAARQDLECGKISLERQNKDLKSRIIHLEGSYRSSKEGLVVQMEARIAELEDR 1161
Query: 377 ADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESE 556
+ E R+RA L R LE + + QV++E D + QLS + + + E E
Sbjct: 1162 LESEERDRANLQLSNRRLERKVKELVMQVDDEHLSLTDQKDQLS---LRLKAMKRQVE-E 1217
Query: 557 GVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEK 670
+ LE +K+KLQ L E + E L ++ +++K
Sbjct: 1218 AEEEIDRLESSKKKLQRELEEQMDMNEHLQGQLNSMKK 1255
Score = 52.8 bits (121), Expect = 1e-06
Identities = 52/236 (22%), Positives = 99/236 (41%), Gaps = 11/236 (4%)
Frame = +2
Query: 29 MGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSK 208
+ E D+L+ K ++ + E+ + L L K +E ++++ + +L ++
Sbjct: 707 LSEMHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIAKEGREDLLRKRERELTALKGA 766
Query: 209 A-DEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADE 385
+E + ++D K++ E L +EEA V L+ + T+
Sbjct: 767 LKEEVSSHDQEMDKLKEQYDAELQALRESVEEATKNVEVLASRSNTSEQDQAGTEMRVKL 826
Query: 386 EARERATLLGKFRNLEHDLDNIREQVEE----EAEGKADLQ------RQLSKANAEAQLW 535
E L G+ LE + ++ Q+E+ EA+ K L+ RQL +A A+
Sbjct: 827 LQEENEKLQGRSEELERRVAQLQRQIEDLKGDEAKAKETLKKYEGEIRQLEEALVHARKE 886
Query: 536 RSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVED 703
+ S A ELE A+ L E ++ E L ++ E+ + RL E+E+
Sbjct: 887 EKEAVSARRALENELEGAQGNLSQTTQEQKQLSEKLKEESEQKEQLR-RLKNEMEN 941
Score = 49.2 bits (112), Expect = 2e-05
Identities = 53/231 (22%), Positives = 105/231 (45%), Gaps = 2/231 (0%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD 214
E +QL++ K K + A+ ++ + + + ++ ++ +L + Q D
Sbjct: 970 ELQNQLDEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDGMRLMEEELRDYQRAQD 1029
Query: 215 EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEAR 394
EA L+ K L E + L++ S++ + + KVS QLE + EE R
Sbjct: 1030 EALTKRQLLEQTLKDLEYE-LEAKSHLKDDRSRLVKQMEAKVS---QLE----MELEEER 1081
Query: 395 ERATLLG-KFRNLEHDLDNIREQVEEEAEGKADLQ-RQLSKANAEAQLWRSKYESEGVAR 568
+ LL + ++ +R + +E + DL+ ++S L EG R
Sbjct: 1082 NNSDLLSERISRSREQMEQLRNGLLQERAARQDLECGKISLERQNKDLKSRIIHLEGSYR 1141
Query: 569 SEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
S + E +++AR+AE E+ +ES + L+ + +RL +V++L ++VD
Sbjct: 1142 SSK-EGLVVQMEARIAELEDRLESEERDRANLQLSNRRLERKVKELVMQVD 1191
Score = 44.0 bits (99), Expect = 6e-04
Identities = 54/240 (22%), Positives = 107/240 (44%), Gaps = 33/240 (13%)
Frame = +2
Query: 98 SEVNDLRAGLDHLSNEKAA-QEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIEN 274
SEV DL L+ E A Q ++ ++++Q N ++ + + L +L + + EN
Sbjct: 607 SEVKDLLEQKSKLTIEVAELQRQLQLEVKNQQN-IKEERERMRANLEELRSQHNEKVEEN 665
Query: 275 SDLLRQLEEAESQ----VSQLSKIKVSLTTQLEDTKRLADE--------------EARER 400
S L ++LEE+E + + +L ++K+ + + L D+ E RE+
Sbjct: 666 STLQQRLEESEGELRKNLEELFQVKMEREQHQTEIRDLQDQLSEMHDELDSAKRSEDREK 725
Query: 401 ATLLGKFRNLEHDL-----------DNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKY 547
L+ + + DL D +R++ E K L+ ++S + E + +Y
Sbjct: 726 GALIEELLQAKQDLQDLLIAKEGREDLLRKRERELTALKGALKEEVSSHDQEMDKLKEQY 785
Query: 548 ESEGVARSEELEEAKRK---LQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEV 718
++E A E +EEA + L +R +E+ +V L++ ++L E+L+ V
Sbjct: 786 DAELQALRESVEEATKNVEVLASRSNTSEQDQAGTEMRVKLLQEENEKLQGRSEELERRV 845
>AL365436-3|CAI16590.1| 1203|Homo sapiens cingulin protein.
Length = 1203
Score = 58.8 bits (136), Expect = 2e-08
Identities = 58/224 (25%), Positives = 105/224 (46%), Gaps = 7/224 (3%)
Frame = +2
Query: 41 LDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEA 220
L+Q + K +++ RA+ ++ L + L E ++ V+ L ++N + + D+
Sbjct: 946 LEQEAENKKRSQDDRAR---QLKGLEEKVSRLETELDEEKNTVELLTDRVNRGRDQVDQL 1002
Query: 221 NRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQ---LSKIKVSLTTQLEDTKRLADE-- 385
L +A++ L + L RQ ++ +++++ K SL+ QLE +L E
Sbjct: 1003 RTELMQERSARQDLECDKISLERQNKDLKTRLASSEGFQKPSASLS-QLESQNQLLQERL 1061
Query: 386 --EARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEG 559
E RE+ L R LE + + Q+E+E + D + QLS +A L R E+E
Sbjct: 1062 QAEEREKTVLQSTNRKLERKVKELSIQIEDERQHVNDQKDQLS-LRVKA-LKRQVDEAE- 1118
Query: 560 VARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLAT 691
E L+ ++K Q + E E E L ++ +LEK R A+
Sbjct: 1119 -EEIERLDGLRKKAQREVEEQHEVNEQLQARIKSLEKDSWRKAS 1161
Score = 53.2 bits (122), Expect = 1e-06
Identities = 51/240 (21%), Positives = 108/240 (45%), Gaps = 5/240 (2%)
Frame = +2
Query: 14 RFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLN 193
R + + E+ +L +L + + Q E+ +++ LD + + E V +LQ++L
Sbjct: 394 RQLEEKTEECSRLQELLERRKGEAQQSNKELQNMKRLLDQGEDLRHGLETQVMELQNKLK 453
Query: 194 EVQSKADEANRTLNDLDAAKKKLS--IENSDLLR-QLEEAESQVSQLS-KIKVSLTTQLE 361
VQ L DL ++ L +E + QL E +++ L +K + ++ +
Sbjct: 454 HVQGPEPAKEVLLKDLLETRELLEEVLEGKQRVEEQLRLRERELTALKGALKEEVASRDQ 513
Query: 362 DTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRS 541
+ + + + R+ L ++ D + + ++ + LQR+L + + E W+S
Sbjct: 514 EVEHVRQQYQRDTEQLRRSMQDATQDHAVLEAERQKMSALVRGLQRELEETSEETGHWQS 573
Query: 542 KYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEK-TKQRLATEVEDLQLEV 718
++ E+L K++L E EE E L +K+ L++ +Q A+ + Q+EV
Sbjct: 574 MFQK----NKEDLRATKQELLQLRMEKEEMEEELGEKIEVLQRELEQARASAGDTRQVEV 629
Score = 45.2 bits (102), Expect = 3e-04
Identities = 59/220 (26%), Positives = 103/220 (46%), Gaps = 6/220 (2%)
Frame = +2
Query: 68 KAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLND--- 238
K E R Q E+ +L+A + S E A + + ++L+ QL ++ +AD R L +
Sbjct: 631 KKELLRTQ--EELKELQA--ERQSQEVAGRHRD-RELEKQLAVLRVEADRG-RELEEQNL 684
Query: 239 -LDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLG 415
L ++L + + + AE++ + L + + ++ T L +T+ DE R +LG
Sbjct: 685 QLQKTLQQLRQDCEEASKAKMVAEAEATVLGQRRAAVETTLRETQEENDEFRRR---ILG 741
Query: 416 KFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEE--LEEA 589
LE L R V+ +A L+ +L + AE Q E+ ++ EE L A
Sbjct: 742 ----LEQQLKETRGLVDGGEAVEARLRDKLQRLEAEKQQLE---EALNASQEEEGSLAAA 794
Query: 590 KRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQ 709
KR L+ARL EA+ + L Q+ L + + + E L+
Sbjct: 795 KRALEARLEEAQRGLARLGQEQQTLNRALEEEGKQREVLR 834
Score = 44.4 bits (100), Expect = 5e-04
Identities = 58/242 (23%), Positives = 109/242 (45%), Gaps = 11/242 (4%)
Frame = +2
Query: 29 MGEQLDQ-LNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQS 205
+GE Q L +L+A+ E + + EV D + ++E + +LQ ++ ++
Sbjct: 861 IGEDSKQALQQLQAQLEDYKEKARREVADAQRQAKDWASEAEKTSGGLSRLQDEIQRLR- 919
Query: 206 KADEANRTLNDLDAAKKKLSIENSDLLRQLEEAE--SQVSQLSKIKVSLTTQLEDTKRLA 379
+A +A++ D K+L + L Q E + SQ + ++K L ++ +
Sbjct: 920 QALQASQAERDTARLDKELLAQRLQGLEQEAENKKRSQDDRARQLK-GLEEKVSRLETEL 978
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQ-RQLSKANAEAQLWRSKYESE 556
DEE L + +D +R ++ +E + DL+ ++S L SE
Sbjct: 979 DEEKNTVELLTDRVNRGRDQVDQLRTELMQERSARQDLECDKISLERQNKDLKTRLASSE 1038
Query: 557 GV----ARSEELEEAKRKLQARL--AEAEETI-ESLNQKVVALEKTKQRLATEVEDLQLE 715
G A +LE + LQ RL E E+T+ +S N+K LE+ + L+ ++ED +
Sbjct: 1039 GFQKPSASLSQLESQNQLLQERLQAEEREKTVLQSTNRK---LERKVKELSIQIEDERQH 1095
Query: 716 VD 721
V+
Sbjct: 1096 VN 1097
>AL136093-4|CAI42826.1| 1253|Homo sapiens myosin VI protein.
Length = 1253
Score = 58.8 bits (136), Expect = 2e-08
Identities = 47/188 (25%), Positives = 89/188 (47%), Gaps = 1/188 (0%)
Frame = +2
Query: 134 LSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQ 313
L + K K +K L+ ++ + +K T + L + +LL L++ + Q
Sbjct: 860 LKDGKPEMNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYDALVKSSEELLSALQKKKQQ 919
Query: 314 VSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADL 493
+ +++ ++ KR ++E R R + R ++ +++ R+Q EEE + + D
Sbjct: 920 EEEAERLRRIQEEMEKERKRREEDEKRRRKE--EEERRMKLEMEAKRKQEEEERKKREDD 977
Query: 494 QRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAE-ETIESLNQKVVALEK 670
++++ +A EAQL R K E E E R+L R+A++E E I Q +AL +
Sbjct: 978 EKRI-QAEVEAQLARQKEEESQQQAVLEQERRDRELALRIAQSEAELISDEAQADLALRR 1036
Query: 671 TKQRLATE 694
LAT+
Sbjct: 1037 GPAVLATK 1044
>AL136093-3|CAI42824.1| 1262|Homo sapiens myosin VI protein.
Length = 1262
Score = 58.8 bits (136), Expect = 2e-08
Identities = 47/188 (25%), Positives = 89/188 (47%), Gaps = 1/188 (0%)
Frame = +2
Query: 134 LSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQ 313
L + K K +K L+ ++ + +K T + L + +LL L++ + Q
Sbjct: 860 LKDGKPEMNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYDALVKSSEELLSALQKKKQQ 919
Query: 314 VSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADL 493
+ +++ ++ KR ++E R R + R ++ +++ R+Q EEE + + D
Sbjct: 920 EEEAERLRRIQEEMEKERKRREEDEKRRRKE--EEERRMKLEMEAKRKQEEEERKKREDD 977
Query: 494 QRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAE-ETIESLNQKVVALEK 670
++++ +A EAQL R K E E E R+L R+A++E E I Q +AL +
Sbjct: 978 EKRI-QAEVEAQLARQKEEESQQQAVLEQERRDRELALRIAQSEAELISDEAQADLALRR 1036
Query: 671 TKQRLATE 694
LAT+
Sbjct: 1037 GPAVLATK 1044
>AL109897-3|CAI19522.1| 1253|Homo sapiens myosin VI protein.
Length = 1253
Score = 58.8 bits (136), Expect = 2e-08
Identities = 47/188 (25%), Positives = 89/188 (47%), Gaps = 1/188 (0%)
Frame = +2
Query: 134 LSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQ 313
L + K K +K L+ ++ + +K T + L + +LL L++ + Q
Sbjct: 860 LKDGKPEMNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYDALVKSSEELLSALQKKKQQ 919
Query: 314 VSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADL 493
+ +++ ++ KR ++E R R + R ++ +++ R+Q EEE + + D
Sbjct: 920 EEEAERLRRIQEEMEKERKRREEDEKRRRKE--EEERRMKLEMEAKRKQEEEERKKREDD 977
Query: 494 QRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAE-ETIESLNQKVVALEK 670
++++ +A EAQL R K E E E R+L R+A++E E I Q +AL +
Sbjct: 978 EKRI-QAEVEAQLARQKEEESQQQAVLEQERRDRELALRIAQSEAELISDEAQADLALRR 1036
Query: 671 TKQRLATE 694
LAT+
Sbjct: 1037 GPAVLATK 1044
>AL109897-2|CAI19520.1| 1262|Homo sapiens myosin VI protein.
Length = 1262
Score = 58.8 bits (136), Expect = 2e-08
Identities = 47/188 (25%), Positives = 89/188 (47%), Gaps = 1/188 (0%)
Frame = +2
Query: 134 LSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQ 313
L + K K +K L+ ++ + +K T + L + +LL L++ + Q
Sbjct: 860 LKDGKPEMNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYDALVKSSEELLSALQKKKQQ 919
Query: 314 VSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADL 493
+ +++ ++ KR ++E R R + R ++ +++ R+Q EEE + + D
Sbjct: 920 EEEAERLRRIQEEMEKERKRREEDEKRRRKE--EEERRMKLEMEAKRKQEEEERKKREDD 977
Query: 494 QRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAE-ETIESLNQKVVALEK 670
++++ +A EAQL R K E E E R+L R+A++E E I Q +AL +
Sbjct: 978 EKRI-QAEVEAQLARQKEEESQQQAVLEQERRDRELALRIAQSEAELISDEAQADLALRR 1036
Query: 671 TKQRLATE 694
LAT+
Sbjct: 1037 GPAVLATK 1044
>AF263462-1|AAF74498.1| 1203|Homo sapiens cingulin protein.
Length = 1203
Score = 58.8 bits (136), Expect = 2e-08
Identities = 58/224 (25%), Positives = 105/224 (46%), Gaps = 7/224 (3%)
Frame = +2
Query: 41 LDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEA 220
L+Q + K +++ RA+ ++ L + L E ++ V+ L ++N + + D+
Sbjct: 946 LEQEAENKKRSQDDRAR---QLKGLEEKVSRLETELDEEKNTVELLTDRVNRGRDQVDQL 1002
Query: 221 NRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQ---LSKIKVSLTTQLEDTKRLADE-- 385
L +A++ L + L RQ ++ +++++ K SL+ QLE +L E
Sbjct: 1003 RTELMQERSARQDLECDKISLERQNKDLKTRLASSEGFQKPSASLS-QLESQNQLLQERL 1061
Query: 386 --EARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEG 559
E RE+ L R LE + + Q+E+E + D + QLS +A L R E+E
Sbjct: 1062 QAEEREKTVLQSTNRKLERKVKELSIQIEDERQHVNDQKDQLS-LRVKA-LKRQVDEAE- 1118
Query: 560 VARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLAT 691
E L+ ++K Q + E E E L ++ +LEK R A+
Sbjct: 1119 -EEIERLDGLRKKAQREVEEQHEVNEQLQARIKSLEKDSWRKAS 1161
Score = 53.2 bits (122), Expect = 1e-06
Identities = 51/240 (21%), Positives = 108/240 (45%), Gaps = 5/240 (2%)
Frame = +2
Query: 14 RFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLN 193
R + + E+ +L +L + + Q E+ +++ LD + + E V +LQ++L
Sbjct: 394 RQLEEKTEECSRLQELLERRKGEAQQSNKELQNMKRLLDQGEDLRHGLETQVMELQNKLK 453
Query: 194 EVQSKADEANRTLNDLDAAKKKLS--IENSDLLR-QLEEAESQVSQLS-KIKVSLTTQLE 361
VQ L DL ++ L +E + QL E +++ L +K + ++ +
Sbjct: 454 HVQGPEPAKEVLLKDLLETRELLEEVLEGKQRVEEQLRLRERELTALKGALKEEVASRDQ 513
Query: 362 DTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRS 541
+ + + + R+ L ++ D + + ++ + LQR+L + + E W+S
Sbjct: 514 EVEHVRQQYQRDTEQLRRSMQDATQDHAVLEAERQKMSALVRGLQRELEETSEETGHWQS 573
Query: 542 KYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEK-TKQRLATEVEDLQLEV 718
++ E+L K++L E EE E L +K+ L++ +Q A+ + Q+EV
Sbjct: 574 MFQK----NKEDLRATKQELLQLRMEKEEMEEELGEKIEVLQRELEQARASAGDTRQVEV 629
Score = 45.2 bits (102), Expect = 3e-04
Identities = 59/220 (26%), Positives = 103/220 (46%), Gaps = 6/220 (2%)
Frame = +2
Query: 68 KAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLND--- 238
K E R Q E+ +L+A + S E A + + ++L+ QL ++ +AD R L +
Sbjct: 631 KKELLRTQ--EELKELQA--ERQSQEVAGRHRD-RELEKQLAVLRVEADRG-RELEEQNL 684
Query: 239 -LDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLG 415
L ++L + + + AE++ + L + + ++ T L +T+ DE R +LG
Sbjct: 685 QLQKTLQQLRQDCEEASKAKMVAEAEATVLGQRRAAVETTLRETQEENDEFRRR---ILG 741
Query: 416 KFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEE--LEEA 589
LE L R V+ +A L+ +L + AE Q E+ ++ EE L A
Sbjct: 742 ----LEQQLKETRGLVDGGEAVEARLRDKLQRLEAEKQQLE---EALNASQEEEGSLAAA 794
Query: 590 KRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQ 709
KR L+ARL EA+ + L Q+ L + + + E L+
Sbjct: 795 KRALEARLEEAQRGLARLGQEQQTLNRALEEEGKQREVLR 834
Score = 44.4 bits (100), Expect = 5e-04
Identities = 58/242 (23%), Positives = 109/242 (45%), Gaps = 11/242 (4%)
Frame = +2
Query: 29 MGEQLDQ-LNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQS 205
+GE Q L +L+A+ E + + EV D + ++E + +LQ ++ ++
Sbjct: 861 IGEDSKQALQQLQAQLEDYKEKARREVADAQRQAKDWASEAEKTSGGLSRLQDEIQRLR- 919
Query: 206 KADEANRTLNDLDAAKKKLSIENSDLLRQLEEAE--SQVSQLSKIKVSLTTQLEDTKRLA 379
+A +A++ D K+L + L Q E + SQ + ++K L ++ +
Sbjct: 920 QALQASQAERDTARLDKELLAQRLQGLEQEAENKKRSQDDRARQLK-GLEEKVSRLETEL 978
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQ-RQLSKANAEAQLWRSKYESE 556
DEE L + +D +R ++ +E + DL+ ++S L SE
Sbjct: 979 DEEKNTVELLTDRVNRGRDQVDQLRTELMQERSARQDLECDKISLERQNKDLKTRLASSE 1038
Query: 557 GV----ARSEELEEAKRKLQARL--AEAEETI-ESLNQKVVALEKTKQRLATEVEDLQLE 715
G A +LE + LQ RL E E+T+ +S N+K LE+ + L+ ++ED +
Sbjct: 1039 GFQKPSASLSQLESQNQLLQERLQAEEREKTVLQSTNRK---LERKVKELSIQIEDERQH 1095
Query: 716 VD 721
V+
Sbjct: 1096 VN 1097
>AB037740-1|BAA92557.1| 1208|Homo sapiens KIAA1319 protein protein.
Length = 1208
Score = 58.8 bits (136), Expect = 2e-08
Identities = 58/224 (25%), Positives = 105/224 (46%), Gaps = 7/224 (3%)
Frame = +2
Query: 41 LDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEA 220
L+Q + K +++ RA+ ++ L + L E ++ V+ L ++N + + D+
Sbjct: 951 LEQEAENKKRSQDDRAR---QLKGLEEKVSRLETELDEEKNTVELLTDRVNRGRDQVDQL 1007
Query: 221 NRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQ---LSKIKVSLTTQLEDTKRLADE-- 385
L +A++ L + L RQ ++ +++++ K SL+ QLE +L E
Sbjct: 1008 RTELMQERSARQDLECDKISLERQNKDLKTRLASSEGFQKPSASLS-QLESQNQLLQERL 1066
Query: 386 --EARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEG 559
E RE+ L R LE + + Q+E+E + D + QLS +A L R E+E
Sbjct: 1067 QAEEREKTVLQSTNRKLERKVKELSIQIEDERQHVNDQKDQLS-LRVKA-LKRQVDEAE- 1123
Query: 560 VARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLAT 691
E L+ ++K Q + E E E L ++ +LEK R A+
Sbjct: 1124 -EEIERLDGLRKKAQREVEEQHEVNEQLQARIKSLEKDSWRKAS 1166
Score = 53.2 bits (122), Expect = 1e-06
Identities = 51/240 (21%), Positives = 108/240 (45%), Gaps = 5/240 (2%)
Frame = +2
Query: 14 RFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLN 193
R + + E+ +L +L + + Q E+ +++ LD + + E V +LQ++L
Sbjct: 399 RQLEEKTEECSRLQELLERRKGEAQQSNKELQNMKRLLDQGEDLRHGLETQVMELQNKLK 458
Query: 194 EVQSKADEANRTLNDLDAAKKKLS--IENSDLLR-QLEEAESQVSQLS-KIKVSLTTQLE 361
VQ L DL ++ L +E + QL E +++ L +K + ++ +
Sbjct: 459 HVQGPEPAKEVLLKDLLETRELLEEVLEGKQRVEEQLRLRERELTALKGALKEEVASRDQ 518
Query: 362 DTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRS 541
+ + + + R+ L ++ D + + ++ + LQR+L + + E W+S
Sbjct: 519 EVEHVRQQYQRDTEQLRRSMQDATQDHAVLEAERQKMSALVRGLQRELEETSEETGHWQS 578
Query: 542 KYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEK-TKQRLATEVEDLQLEV 718
++ E+L K++L E EE E L +K+ L++ +Q A+ + Q+EV
Sbjct: 579 MFQK----NKEDLRATKQELLQLRMEKEEMEEELGEKIEVLQRELEQARASAGDTRQVEV 634
Score = 45.2 bits (102), Expect = 3e-04
Identities = 59/220 (26%), Positives = 103/220 (46%), Gaps = 6/220 (2%)
Frame = +2
Query: 68 KAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLND--- 238
K E R Q E+ +L+A + S E A + + ++L+ QL ++ +AD R L +
Sbjct: 636 KKELLRTQ--EELKELQA--ERQSQEVAGRHRD-RELEKQLAVLRVEADRG-RELEEQNL 689
Query: 239 -LDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLG 415
L ++L + + + AE++ + L + + ++ T L +T+ DE R +LG
Sbjct: 690 QLQKTLQQLRQDCEEASKAKMVAEAEATVLGQRRAAVETTLRETQEENDEFRRR---ILG 746
Query: 416 KFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEE--LEEA 589
LE L R V+ +A L+ +L + AE Q E+ ++ EE L A
Sbjct: 747 ----LEQQLKETRGLVDGGEAVEARLRDKLQRLEAEKQQLE---EALNASQEEEGSLAAA 799
Query: 590 KRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQ 709
KR L+ARL EA+ + L Q+ L + + + E L+
Sbjct: 800 KRALEARLEEAQRGLARLGQEQQTLNRALEEEGKQREVLR 839
Score = 44.4 bits (100), Expect = 5e-04
Identities = 58/242 (23%), Positives = 109/242 (45%), Gaps = 11/242 (4%)
Frame = +2
Query: 29 MGEQLDQ-LNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQS 205
+GE Q L +L+A+ E + + EV D + ++E + +LQ ++ ++
Sbjct: 866 IGEDSKQALQQLQAQLEDYKEKARREVADAQRQAKDWASEAEKTSGGLSRLQDEIQRLR- 924
Query: 206 KADEANRTLNDLDAAKKKLSIENSDLLRQLEEAE--SQVSQLSKIKVSLTTQLEDTKRLA 379
+A +A++ D K+L + L Q E + SQ + ++K L ++ +
Sbjct: 925 QALQASQAERDTARLDKELLAQRLQGLEQEAENKKRSQDDRARQLK-GLEEKVSRLETEL 983
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQ-RQLSKANAEAQLWRSKYESE 556
DEE L + +D +R ++ +E + DL+ ++S L SE
Sbjct: 984 DEEKNTVELLTDRVNRGRDQVDQLRTELMQERSARQDLECDKISLERQNKDLKTRLASSE 1043
Query: 557 GV----ARSEELEEAKRKLQARL--AEAEETI-ESLNQKVVALEKTKQRLATEVEDLQLE 715
G A +LE + LQ RL E E+T+ +S N+K LE+ + L+ ++ED +
Sbjct: 1044 GFQKPSASLSQLESQNQLLQERLQAEEREKTVLQSTNRK---LERKVKELSIQIEDERQH 1100
Query: 716 VD 721
V+
Sbjct: 1101 VN 1102
>X03445-1|CAA27174.1| 572|Homo sapiens protein ( Human mRNA for
nuclear envelope protein lamin C precursor. ).
Length = 572
Score = 58.0 bits (134), Expect = 4e-08
Identities = 48/200 (24%), Positives = 104/200 (52%), Gaps = 9/200 (4%)
Frame = +2
Query: 152 AQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSK 331
++E + +++ +++ +A +TL+ + + +L +E S + + +E +++ ++
Sbjct: 66 SEEVVSREVSGIKAAYEAELGDARKTLDSVAKERARLQLELSKVREEFKELKARNTKKEG 125
Query: 332 IKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVE--EEAEGKADLQRQ- 502
++ +L+D + L + + +T L + R LE +L ++R QV E A G+A Q Q
Sbjct: 126 DLIAAQARLKDLEALLNSKEAALSTALSEKRTLEGELHDLRGQVAKLEAALGEAKKQLQD 185
Query: 503 --LSKANAEAQLWRSKYESEGVAR--SEELEEAKRKLQARLAEAE--ETIESLNQKVVAL 664
L + +AE +L K E + SEEL E KR+ + RL E + + E ++ AL
Sbjct: 186 EMLRRVDAENRLQTMKEELDFQKNIYSEELRETKRRHETRLVEIDNGKQREFESRLADAL 245
Query: 665 EKTKQRLATEVEDLQLEVDR 724
++ + + +VE + E+++
Sbjct: 246 QELRAQHEDQVEQYKKELEK 265
Score = 34.3 bits (75), Expect = 0.50
Identities = 31/144 (21%), Positives = 62/144 (43%), Gaps = 1/144 (0%)
Frame = +2
Query: 128 DHLSNEKAAQEKIVKQLQHQLNEVQS-KADEANRTLNDLDAAKKKLSIENSDLLRQLEEA 304
D L +A E V+Q + +L + S K D A ++ + + + +L +
Sbjct: 243 DALQELRAQHEDQVEQYKKELEKTYSAKLDNARQSA---ERNSNLVGAAHEELQQSRIRI 299
Query: 305 ESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGK 484
+S +QLS+++ L + + L D ARER T E ++ +R +++++ +
Sbjct: 300 DSLSAQLSQLQKQLAAKEAKLRDLEDSLARERDTSRRLLAEKEREMAEMRARMQQQLDEY 359
Query: 485 ADLQRQLSKANAEAQLWRSKYESE 556
+L + E +R E E
Sbjct: 360 QELLDIKLALDMEIHAYRKLLEGE 383
>X03444-1|CAA27173.1| 702|Homo sapiens protein ( Human mRNA for
nuclear envelope protein lamin A precursor. ).
Length = 702
Score = 58.0 bits (134), Expect = 4e-08
Identities = 48/200 (24%), Positives = 104/200 (52%), Gaps = 9/200 (4%)
Frame = +2
Query: 152 AQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSK 331
++E + +++ +++ +A +TL+ + + +L +E S + + +E +++ ++
Sbjct: 66 SEEVVSREVSGIKAAYEAELGDARKTLDSVAKERARLQLELSKVREEFKELKARNTKKEG 125
Query: 332 IKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVE--EEAEGKADLQRQ- 502
++ +L+D + L + + +T L + R LE +L ++R QV E A G+A Q Q
Sbjct: 126 DLIAAQARLKDLEALLNSKEAALSTALSEKRTLEGELHDLRGQVAKLEAALGEAKKQLQD 185
Query: 503 --LSKANAEAQLWRSKYESEGVAR--SEELEEAKRKLQARLAEAE--ETIESLNQKVVAL 664
L + +AE +L K E + SEEL E KR+ + RL E + + E ++ AL
Sbjct: 186 EMLRRVDAENRLQTMKEELDFQKNIYSEELRETKRRHETRLVEIDNGKQREFESRLADAL 245
Query: 665 EKTKQRLATEVEDLQLEVDR 724
++ + + +VE + E+++
Sbjct: 246 QELRAQHEDQVEQYKKELEK 265
Score = 34.3 bits (75), Expect = 0.50
Identities = 31/144 (21%), Positives = 62/144 (43%), Gaps = 1/144 (0%)
Frame = +2
Query: 128 DHLSNEKAAQEKIVKQLQHQLNEVQS-KADEANRTLNDLDAAKKKLSIENSDLLRQLEEA 304
D L +A E V+Q + +L + S K D A ++ + + + +L +
Sbjct: 243 DALQELRAQHEDQVEQYKKELEKTYSAKLDNARQSA---ERNSNLVGAAHEELQQSRIRI 299
Query: 305 ESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGK 484
+S +QLS+++ L + + L D ARER T E ++ +R +++++ +
Sbjct: 300 DSLSAQLSQLQKQLAAKEAKLRDLEDSLARERDTSRRLLAEKEREMAEMRARMQQQLDEY 359
Query: 485 ADLQRQLSKANAEAQLWRSKYESE 556
+L + E +R E E
Sbjct: 360 QELLDIKLALDMEIHAYRKLLEGE 383
>M13451-1|AAA36164.1| 572|Homo sapiens protein ( Human lamin C
mRNA, complete cds. ).
Length = 572
Score = 58.0 bits (134), Expect = 4e-08
Identities = 48/200 (24%), Positives = 104/200 (52%), Gaps = 9/200 (4%)
Frame = +2
Query: 152 AQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSK 331
++E + +++ +++ +A +TL+ + + +L +E S + + +E +++ ++
Sbjct: 66 SEEVVSREVSGIKAAYEAELGDARKTLDSVAKERARLQLELSKVREEFKELKARNTKKEG 125
Query: 332 IKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVE--EEAEGKADLQRQ- 502
++ +L+D + L + + +T L + R LE +L ++R QV E A G+A Q Q
Sbjct: 126 DLIAAQARLKDLEALLNSKEAALSTALSEKRTLEGELHDLRGQVAKLEAALGEAKKQLQD 185
Query: 503 --LSKANAEAQLWRSKYESEGVAR--SEELEEAKRKLQARLAEAE--ETIESLNQKVVAL 664
L + +AE +L K E + SEEL E KR+ + RL E + + E ++ AL
Sbjct: 186 EMLRRVDAENRLQTMKEELDFQKNIYSEELRETKRRHETRLVEIDNGKQREFESRLADAL 245
Query: 665 EKTKQRLATEVEDLQLEVDR 724
++ + + +VE + E+++
Sbjct: 246 QELRAQHEDQVEQYKKELEK 265
Score = 34.3 bits (75), Expect = 0.50
Identities = 31/144 (21%), Positives = 62/144 (43%), Gaps = 1/144 (0%)
Frame = +2
Query: 128 DHLSNEKAAQEKIVKQLQHQLNEVQS-KADEANRTLNDLDAAKKKLSIENSDLLRQLEEA 304
D L +A E V+Q + +L + S K D A ++ + + + +L +
Sbjct: 243 DALQELRAQHEDQVEQYKKELEKTYSAKLDNARQSA---ERNSNLVGAAHEELQQSRIRI 299
Query: 305 ESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGK 484
+S +QLS+++ L + + L D ARER T E ++ +R +++++ +
Sbjct: 300 DSLSAQLSQLQKQLAAKEAKLRDLEDSLARERDTSRRLLAEKEREMAEMRARMQQQLDEY 359
Query: 485 ADLQRQLSKANAEAQLWRSKYESE 556
+L + E +R E E
Sbjct: 360 QELLDIKLALDMEIHAYRKLLEGE 383
>BT007441-1|AAP36109.1| 600|Homo sapiens lamin B1 protein.
Length = 600
Score = 58.0 bits (134), Expect = 4e-08
Identities = 50/183 (27%), Positives = 91/183 (49%), Gaps = 4/183 (2%)
Frame = +2
Query: 185 QLNEVQSKAD--EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVS-QLSKIKVSLTTQ 355
+L+ +Q K + E N L + L +EN LL ++ E E + ++S IK ++
Sbjct: 20 RLSRLQEKEELRELNDRLAHYIDRVRALELENDRLLLKISEKEEVTTREVSGIKALYESE 79
Query: 356 LEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLW 535
L D +R+ DE ARERA L + L +LD + + ++ EG+ + + K + E+
Sbjct: 80 LADARRVLDETARERARLQIEIGKLRAELDEVNKSAKKR-EGELTVAQGRVK-DLESLFH 137
Query: 536 RSKYE-SEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQL 712
RS+ E + ++ LE +L+A+LA+AE+ +++ + L + LQ
Sbjct: 138 RSEVELAAALSDKRGLESDVAELRAQLAKAEDGHAVAKKQLEKETLMRVDLENRCQSLQE 197
Query: 713 EVD 721
E+D
Sbjct: 198 ELD 200
Score = 44.0 bits (99), Expect = 6e-04
Identities = 55/232 (23%), Positives = 100/232 (43%), Gaps = 2/232 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+ + +LD++NK K E V DL + E AA + L+ + E+
Sbjct: 101 IGKLRAELDEVNKSAKKREGELTVAQGRVKDLESLFHRSEVELAAALSDKRGLESDVAEL 160
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLR-QLE-EAESQVSQLSKIKVSLTTQLEDTKR 373
+++ +A D A KK +E L+R LE +S +L K ++ +T+R
Sbjct: 161 RAQLAKA----EDGHAVAKK-QLEKETLMRVDLENRCQSLQEELDFRKSVFEEEVRETRR 215
Query: 374 LADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYES 553
R + R E+D Q EE + D Q +L K E Q +++K +S
Sbjct: 216 ----RHERRLVEVDSSRQQEYDFK--MAQALEELRSQHDEQVRLYKLELE-QTYQAKLDS 268
Query: 554 EGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQ 709
++ S++ ++A + L EA +ESL+ ++ L+K + +L+
Sbjct: 269 AKLS-SDQNDKAASAAREELKEARMRLESLSYQLSGLQKQASAAEDRIRELE 319
>BC014507-1|AAH14507.1| 664|Homo sapiens lamin A/C protein.
Length = 664
Score = 58.0 bits (134), Expect = 4e-08
Identities = 48/200 (24%), Positives = 104/200 (52%), Gaps = 9/200 (4%)
Frame = +2
Query: 152 AQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSK 331
++E + +++ +++ +A +TL+ + + +L +E S + + +E +++ ++
Sbjct: 66 SEEVVSREVSGIKAAYEAELGDARKTLDSVAKERARLQLELSKVREEFKELKARNTKKEG 125
Query: 332 IKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVE--EEAEGKADLQRQ- 502
++ +L+D + L + + +T L + R LE +L ++R QV E A G+A Q Q
Sbjct: 126 DLIAAQARLKDLEALLNSKEAALSTALSEKRTLEGELHDLRGQVAKLEAALGEAKKQLQD 185
Query: 503 --LSKANAEAQLWRSKYESEGVAR--SEELEEAKRKLQARLAEAE--ETIESLNQKVVAL 664
L + +AE +L K E + SEEL E KR+ + RL E + + E ++ AL
Sbjct: 186 EMLRRVDAENRLQTMKEELDFQKNIYSEELRETKRRHETRLVEIDNGKQREFESRLADAL 245
Query: 665 EKTKQRLATEVEDLQLEVDR 724
++ + + +VE + E+++
Sbjct: 246 QELRAQHEDQVEQYKKELEK 265
Score = 34.3 bits (75), Expect = 0.50
Identities = 31/144 (21%), Positives = 62/144 (43%), Gaps = 1/144 (0%)
Frame = +2
Query: 128 DHLSNEKAAQEKIVKQLQHQLNEVQS-KADEANRTLNDLDAAKKKLSIENSDLLRQLEEA 304
D L +A E V+Q + +L + S K D A ++ + + + +L +
Sbjct: 243 DALQELRAQHEDQVEQYKKELEKTYSAKLDNARQSA---ERNSNLVGAAHEELQQSRIRI 299
Query: 305 ESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGK 484
+S +QLS+++ L + + L D ARER T E ++ +R +++++ +
Sbjct: 300 DSLSAQLSQLQKQLAAKEAKLRDLEDSLARERDTSRRLLAEKEREMAEMRARMQQQLDEY 359
Query: 485 ADLQRQLSKANAEAQLWRSKYESE 556
+L + E +R E E
Sbjct: 360 QELLDIKLALDMEIHAYRKLLEGE 383
>BC006551-1|AAH06551.1| 600|Homo sapiens lamin B2 protein.
Length = 600
Score = 58.0 bits (134), Expect = 4e-08
Identities = 50/183 (27%), Positives = 91/183 (49%), Gaps = 4/183 (2%)
Frame = +2
Query: 185 QLNEVQSKAD--EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVS-QLSKIKVSLTTQ 355
+L+ +Q K + E N L + L +EN LL ++ E E + ++S IK ++
Sbjct: 20 RLSRLQEKEELRELNDRLAHYIDRVRALELENDRLLLKISEKEEVTTREVSGIKALYESE 79
Query: 356 LEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLW 535
L D +R+ DE ARERA L + L +LD + + ++ EG+ + + K + E+
Sbjct: 80 LADARRVLDETARERARLQIEIGKLRAELDEVNKSAKKR-EGELTVAQGRVK-DLESLFH 137
Query: 536 RSKYE-SEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQL 712
RS+ E + ++ LE +L+A+LA+AE+ +++ + L + LQ
Sbjct: 138 RSEVELAAALSDKRGLESDVAELRAQLAKAEDGHAVAKKQLEKETLMRVDLENRCQSLQE 197
Query: 713 EVD 721
E+D
Sbjct: 198 ELD 200
Score = 44.0 bits (99), Expect = 6e-04
Identities = 55/232 (23%), Positives = 100/232 (43%), Gaps = 2/232 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+ + +LD++NK K E V DL + E AA + L+ + E+
Sbjct: 101 IGKLRAELDEVNKSAKKREGELTVAQGRVKDLESLFHRSEVELAAALSDKRGLESDVAEL 160
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLR-QLE-EAESQVSQLSKIKVSLTTQLEDTKR 373
+++ +A D A KK +E L+R LE +S +L K ++ +T+R
Sbjct: 161 RAQLAKA----EDGHAVAKK-QLEKETLMRVDLENRCQSLQEELDFRKSVFEEEVRETRR 215
Query: 374 LADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYES 553
R + R E+D Q EE + D Q +L K E Q +++K +S
Sbjct: 216 ----RHERRLVEVDSSRQQEYDFK--MAQALEELRSQHDEQVRLYKLELE-QTYQAKLDS 268
Query: 554 EGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQ 709
++ S++ ++A + L EA +ESL+ ++ L+K + +L+
Sbjct: 269 AKLS-SDQNDKAASAAREELKEARMRLESLSYQLSGLQKQASAAEDRIRELE 319
>BC003162-1|AAH03162.1| 572|Homo sapiens lamin A/C protein.
Length = 572
Score = 58.0 bits (134), Expect = 4e-08
Identities = 48/200 (24%), Positives = 104/200 (52%), Gaps = 9/200 (4%)
Frame = +2
Query: 152 AQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSK 331
++E + +++ +++ +A +TL+ + + +L +E S + + +E +++ ++
Sbjct: 66 SEEVVSREVSGIKAAYEAELGDARKTLDSVAKERARLQLELSKVREEFKELKARNTKKEG 125
Query: 332 IKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVE--EEAEGKADLQRQ- 502
++ +L+D + L + + +T L + R LE +L ++R QV E A G+A Q Q
Sbjct: 126 DLIAAQARLKDLEALLNSKEAALSTALSEKRTLEGELHDLRGQVAKLEAALGEAKKQLQD 185
Query: 503 --LSKANAEAQLWRSKYESEGVAR--SEELEEAKRKLQARLAEAE--ETIESLNQKVVAL 664
L + +AE +L K E + SEEL E KR+ + RL E + + E ++ AL
Sbjct: 186 EMLRRVDAENRLQTMKEELDFQKNIYSEELRETKRRHETRLVEIDNGKQREFESRLADAL 245
Query: 665 EKTKQRLATEVEDLQLEVDR 724
++ + + +VE + E+++
Sbjct: 246 QELRAQHEDQVEQYKKELEK 265
Score = 34.3 bits (75), Expect = 0.50
Identities = 31/144 (21%), Positives = 62/144 (43%), Gaps = 1/144 (0%)
Frame = +2
Query: 128 DHLSNEKAAQEKIVKQLQHQLNEVQS-KADEANRTLNDLDAAKKKLSIENSDLLRQLEEA 304
D L +A E V+Q + +L + S K D A ++ + + + +L +
Sbjct: 243 DALQELRAQHEDQVEQYKKELEKTYSAKLDNARQSA---ERNSNLVGAAHEELQQSRIRI 299
Query: 305 ESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGK 484
+S +QLS+++ L + + L D ARER T E ++ +R +++++ +
Sbjct: 300 DSLSAQLSQLQKQLAAKEAKLRDLEDSLARERDTSRRLLAEKEREMAEMRARMQQQLDEY 359
Query: 485 ADLQRQLSKANAEAQLWRSKYESE 556
+L + E +R E E
Sbjct: 360 QELLDIKLALDMEIHAYRKLLEGE 383
>BC000511-1|AAH00511.1| 572|Homo sapiens lamin A/C protein.
Length = 572
Score = 58.0 bits (134), Expect = 4e-08
Identities = 48/200 (24%), Positives = 104/200 (52%), Gaps = 9/200 (4%)
Frame = +2
Query: 152 AQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSK 331
++E + +++ +++ +A +TL+ + + +L +E S + + +E +++ ++
Sbjct: 66 SEEVVSREVSGIKAAYEAELGDARKTLDSVAKERARLQLELSKVREEFKELKARNTKKEG 125
Query: 332 IKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVE--EEAEGKADLQRQ- 502
++ +L+D + L + + +T L + R LE +L ++R QV E A G+A Q Q
Sbjct: 126 DLIAAQARLKDLEALLNSKEAALSTALSEKRTLEGELHDLRGQVAKLEAALGEAKKQLQD 185
Query: 503 --LSKANAEAQLWRSKYESEGVAR--SEELEEAKRKLQARLAEAE--ETIESLNQKVVAL 664
L + +AE +L K E + SEEL E KR+ + RL E + + E ++ AL
Sbjct: 186 EMLRRVDAENRLQTMKEELDFQKNIYSEELRETKRRHETRLVEIDNGKQREFESRLADAL 245
Query: 665 EKTKQRLATEVEDLQLEVDR 724
++ + + +VE + E+++
Sbjct: 246 QELRAQHEDQVEQYKKELEK 265
Score = 34.3 bits (75), Expect = 0.50
Identities = 31/144 (21%), Positives = 62/144 (43%), Gaps = 1/144 (0%)
Frame = +2
Query: 128 DHLSNEKAAQEKIVKQLQHQLNEVQS-KADEANRTLNDLDAAKKKLSIENSDLLRQLEEA 304
D L +A E V+Q + +L + S K D A ++ + + + +L +
Sbjct: 243 DALQELRAQHEDQVEQYKKELEKTYSAKLDNARQSA---ERNSNLVGAAHEELQQSRIRI 299
Query: 305 ESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGK 484
+S +QLS+++ L + + L D ARER T E ++ +R +++++ +
Sbjct: 300 DSLSAQLSQLQKQLAAKEAKLRDLEDSLARERDTSRRLLAEKEREMAEMRARMQQQLDEY 359
Query: 485 ADLQRQLSKANAEAQLWRSKYESE 556
+L + E +R E E
Sbjct: 360 QELLDIKLALDMEIHAYRKLLEGE 383
>AY847597-1|AAW32540.1| 664|Homo sapiens lamin A/C transcript
variant 1 protein.
Length = 664
Score = 58.0 bits (134), Expect = 4e-08
Identities = 48/200 (24%), Positives = 104/200 (52%), Gaps = 9/200 (4%)
Frame = +2
Query: 152 AQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSK 331
++E + +++ +++ +A +TL+ + + +L +E S + + +E +++ ++
Sbjct: 66 SEEVVSREVSGIKAAYEAELGDARKTLDSVAKERARLQLELSKVREEFKELKARNTKKEG 125
Query: 332 IKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVE--EEAEGKADLQRQ- 502
++ +L+D + L + + +T L + R LE +L ++R QV E A G+A Q Q
Sbjct: 126 DLIAAQARLKDLEALLNSKEAALSTALSEKRTLEGELHDLRGQVAKLEAALGEAKKQLQD 185
Query: 503 --LSKANAEAQLWRSKYESEGVAR--SEELEEAKRKLQARLAEAE--ETIESLNQKVVAL 664
L + +AE +L K E + SEEL E KR+ + RL E + + E ++ AL
Sbjct: 186 EMLRRVDAENRLQTMKEELDFQKNIYSEELRETKRRHETRLVEIDNGKQREFESRLADAL 245
Query: 665 EKTKQRLATEVEDLQLEVDR 724
++ + + +VE + E+++
Sbjct: 246 QELRAQHEDQVEQYKKELEK 265
Score = 34.3 bits (75), Expect = 0.50
Identities = 31/144 (21%), Positives = 62/144 (43%), Gaps = 1/144 (0%)
Frame = +2
Query: 128 DHLSNEKAAQEKIVKQLQHQLNEVQS-KADEANRTLNDLDAAKKKLSIENSDLLRQLEEA 304
D L +A E V+Q + +L + S K D A ++ + + + +L +
Sbjct: 243 DALQELRAQHEDQVEQYKKELEKTYSAKLDNARQSA---ERNSNLVGAAHEELQQSRIRI 299
Query: 305 ESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGK 484
+S +QLS+++ L + + L D ARER T E ++ +R +++++ +
Sbjct: 300 DSLSAQLSQLQKQLAAKEAKLRDLEDSLARERDTSRRLLAEKEREMAEMRARMQQQLDEY 359
Query: 485 ADLQRQLSKANAEAQLWRSKYESE 556
+L + E +R E E
Sbjct: 360 QELLDIKLALDMEIHAYRKLLEGE 383
>AY847596-1|AAW32539.1| 480|Homo sapiens lamin A/C transcript
variant 1 protein.
Length = 480
Score = 58.0 bits (134), Expect = 4e-08
Identities = 48/200 (24%), Positives = 104/200 (52%), Gaps = 9/200 (4%)
Frame = +2
Query: 152 AQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSK 331
++E + +++ +++ +A +TL+ + + +L +E S + + +E +++ ++
Sbjct: 66 SEEVVSREVSGIKAAYEAELGDARKTLDSVAKERARLQLELSKVREEFKELKARNTKKEG 125
Query: 332 IKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVE--EEAEGKADLQRQ- 502
++ +L+D + L + + +T L + R LE +L ++R QV E A G+A Q Q
Sbjct: 126 DLIAAQARLKDLEALLNSKEAALSTALSEKRTLEGELHDLRGQVAKLEAALGEAKKQLQD 185
Query: 503 --LSKANAEAQLWRSKYESEGVAR--SEELEEAKRKLQARLAEAE--ETIESLNQKVVAL 664
L + +AE +L K E + SEEL E KR+ + RL E + + E ++ AL
Sbjct: 186 EMLRRVDAENRLQTMKEELDFQKNIYSEELRETKRRHETRLVEIDNGKQREFESRLADAL 245
Query: 665 EKTKQRLATEVEDLQLEVDR 724
++ + + +VE + E+++
Sbjct: 246 QELRAQHEDQVEQYKKELEK 265
Score = 34.3 bits (75), Expect = 0.50
Identities = 31/144 (21%), Positives = 62/144 (43%), Gaps = 1/144 (0%)
Frame = +2
Query: 128 DHLSNEKAAQEKIVKQLQHQLNEVQS-KADEANRTLNDLDAAKKKLSIENSDLLRQLEEA 304
D L +A E V+Q + +L + S K D A ++ + + + +L +
Sbjct: 243 DALQELRAQHEDQVEQYKKELEKTYSAKLDNARQSA---ERNSNLVGAAHEELQQSRIRI 299
Query: 305 ESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGK 484
+S +QLS+++ L + + L D ARER T E ++ +R +++++ +
Sbjct: 300 DSLSAQLSQLQKQLAAKEAKLRDLEDSLARERDTSRRLLAEKEREMAEMRARMQQQLDEY 359
Query: 485 ADLQRQLSKANAEAQLWRSKYESE 556
+L + E +R E E
Sbjct: 360 QELLDIKLALDMEIHAYRKLLEGE 383
>AY528714-1|ABB04050.1| 487|Homo sapiens rhabdomyosarcoma antigen
MU-RMS-40.12 protein.
Length = 487
Score = 58.0 bits (134), Expect = 4e-08
Identities = 48/200 (24%), Positives = 104/200 (52%), Gaps = 9/200 (4%)
Frame = +2
Query: 152 AQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSK 331
++E + +++ +++ +A +TL+ + + +L +E S + + +E +++ ++
Sbjct: 66 SEEVVSREVSGIKAAYEAELGDARKTLDSVAKERARLQLELSKVREEFKELKARNTKKEG 125
Query: 332 IKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVE--EEAEGKADLQRQ- 502
++ +L+D + L + + +T L + R LE +L ++R QV E A G+A Q Q
Sbjct: 126 DLIAAQARLKDLEALLNSKEAALSTALSEKRTLEGELHDLRGQVAKLEAALGEAKKQLQD 185
Query: 503 --LSKANAEAQLWRSKYESEGVAR--SEELEEAKRKLQARLAEAE--ETIESLNQKVVAL 664
L + +AE +L K E + SEEL E KR+ + RL E + + E ++ AL
Sbjct: 186 EMLRRVDAENRLQTMKEELDFQKNIYSEELRETKRRHETRLVEIDNGKQREFESRLADAL 245
Query: 665 EKTKQRLATEVEDLQLEVDR 724
++ + + +VE + E+++
Sbjct: 246 QELRAQHEDQVEQYKKELEK 265
Score = 34.3 bits (75), Expect = 0.50
Identities = 31/144 (21%), Positives = 62/144 (43%), Gaps = 1/144 (0%)
Frame = +2
Query: 128 DHLSNEKAAQEKIVKQLQHQLNEVQS-KADEANRTLNDLDAAKKKLSIENSDLLRQLEEA 304
D L +A E V+Q + +L + S K D A ++ + + + +L +
Sbjct: 243 DALQELRAQHEDQVEQYKKELEKTYSAKLDNARQSA---ERNSNLVGAAHEELQQSRIRI 299
Query: 305 ESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGK 484
+S +QLS+++ L + + L D ARER T E ++ +R +++++ +
Sbjct: 300 DSLSAQLSQLQKQLAAKEAKLRDLEDSLARERDTSRRLLAEKEREMAEMRARMQQQLDEY 359
Query: 485 ADLQRQLSKANAEAQLWRSKYESE 556
+L + E +R E E
Sbjct: 360 QELLDIKLALDMEIHAYRKLLEGE 383
>AY357727-1|AAR29466.1| 614|Homo sapiens progerin protein.
Length = 614
Score = 58.0 bits (134), Expect = 4e-08
Identities = 48/200 (24%), Positives = 104/200 (52%), Gaps = 9/200 (4%)
Frame = +2
Query: 152 AQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSK 331
++E + +++ +++ +A +TL+ + + +L +E S + + +E +++ ++
Sbjct: 66 SEEVVSREVSGIKAAYEAELGDARKTLDSVAKERARLQLELSKVREEFKELKARNTKKEG 125
Query: 332 IKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVE--EEAEGKADLQRQ- 502
++ +L+D + L + + +T L + R LE +L ++R QV E A G+A Q Q
Sbjct: 126 DLIAAQARLKDLEALLNSKEAALSTALSEKRTLEGELHDLRGQVAKLEAALGEAKKQLQD 185
Query: 503 --LSKANAEAQLWRSKYESEGVAR--SEELEEAKRKLQARLAEAE--ETIESLNQKVVAL 664
L + +AE +L K E + SEEL E KR+ + RL E + + E ++ AL
Sbjct: 186 EMLRRVDAENRLQTMKEELDFQKNIYSEELRETKRRHETRLVEIDNGKQREFESRLADAL 245
Query: 665 EKTKQRLATEVEDLQLEVDR 724
++ + + +VE + E+++
Sbjct: 246 QELRAQHEDQVEQYKKELEK 265
Score = 34.3 bits (75), Expect = 0.50
Identities = 31/144 (21%), Positives = 62/144 (43%), Gaps = 1/144 (0%)
Frame = +2
Query: 128 DHLSNEKAAQEKIVKQLQHQLNEVQS-KADEANRTLNDLDAAKKKLSIENSDLLRQLEEA 304
D L +A E V+Q + +L + S K D A ++ + + + +L +
Sbjct: 243 DALQELRAQHEDQVEQYKKELEKTYSAKLDNARQSA---ERNSNLVGAAHEELQQSRIRI 299
Query: 305 ESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGK 484
+S +QLS+++ L + + L D ARER T E ++ +R +++++ +
Sbjct: 300 DSLSAQLSQLQKQLAAKEAKLRDLEDSLARERDTSRRLLAEKEREMAEMRARMQQQLDEY 359
Query: 485 ADLQRQLSKANAEAQLWRSKYESE 556
+L + E +R E E
Sbjct: 360 QELLDIKLALDMEIHAYRKLLEGE 383
>AL135927-4|CAI15522.1| 664|Homo sapiens lamin A/C protein.
Length = 664
Score = 58.0 bits (134), Expect = 4e-08
Identities = 48/200 (24%), Positives = 104/200 (52%), Gaps = 9/200 (4%)
Frame = +2
Query: 152 AQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSK 331
++E + +++ +++ +A +TL+ + + +L +E S + + +E +++ ++
Sbjct: 66 SEEVVSREVSGIKAAYEAELGDARKTLDSVAKERARLQLELSKVREEFKELKARNTKKEG 125
Query: 332 IKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVE--EEAEGKADLQRQ- 502
++ +L+D + L + + +T L + R LE +L ++R QV E A G+A Q Q
Sbjct: 126 DLIAAQARLKDLEALLNSKEAALSTALSEKRTLEGELHDLRGQVAKLEAALGEAKKQLQD 185
Query: 503 --LSKANAEAQLWRSKYESEGVAR--SEELEEAKRKLQARLAEAE--ETIESLNQKVVAL 664
L + +AE +L K E + SEEL E KR+ + RL E + + E ++ AL
Sbjct: 186 EMLRRVDAENRLQTMKEELDFQKNIYSEELRETKRRHETRLVEIDNGKQREFESRLADAL 245
Query: 665 EKTKQRLATEVEDLQLEVDR 724
++ + + +VE + E+++
Sbjct: 246 QELRAQHEDQVEQYKKELEK 265
Score = 34.3 bits (75), Expect = 0.50
Identities = 31/144 (21%), Positives = 62/144 (43%), Gaps = 1/144 (0%)
Frame = +2
Query: 128 DHLSNEKAAQEKIVKQLQHQLNEVQS-KADEANRTLNDLDAAKKKLSIENSDLLRQLEEA 304
D L +A E V+Q + +L + S K D A ++ + + + +L +
Sbjct: 243 DALQELRAQHEDQVEQYKKELEKTYSAKLDNARQSA---ERNSNLVGAAHEELQQSRIRI 299
Query: 305 ESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGK 484
+S +QLS+++ L + + L D ARER T E ++ +R +++++ +
Sbjct: 300 DSLSAQLSQLQKQLAAKEAKLRDLEDSLARERDTSRRLLAEKEREMAEMRARMQQQLDEY 359
Query: 485 ADLQRQLSKANAEAQLWRSKYESE 556
+L + E +R E E
Sbjct: 360 QELLDIKLALDMEIHAYRKLLEGE 383
>AL135927-3|CAI15523.1| 614|Homo sapiens lamin A/C protein.
Length = 614
Score = 58.0 bits (134), Expect = 4e-08
Identities = 48/200 (24%), Positives = 104/200 (52%), Gaps = 9/200 (4%)
Frame = +2
Query: 152 AQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSK 331
++E + +++ +++ +A +TL+ + + +L +E S + + +E +++ ++
Sbjct: 66 SEEVVSREVSGIKAAYEAELGDARKTLDSVAKERARLQLELSKVREEFKELKARNTKKEG 125
Query: 332 IKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVE--EEAEGKADLQRQ- 502
++ +L+D + L + + +T L + R LE +L ++R QV E A G+A Q Q
Sbjct: 126 DLIAAQARLKDLEALLNSKEAALSTALSEKRTLEGELHDLRGQVAKLEAALGEAKKQLQD 185
Query: 503 --LSKANAEAQLWRSKYESEGVAR--SEELEEAKRKLQARLAEAE--ETIESLNQKVVAL 664
L + +AE +L K E + SEEL E KR+ + RL E + + E ++ AL
Sbjct: 186 EMLRRVDAENRLQTMKEELDFQKNIYSEELRETKRRHETRLVEIDNGKQREFESRLADAL 245
Query: 665 EKTKQRLATEVEDLQLEVDR 724
++ + + +VE + E+++
Sbjct: 246 QELRAQHEDQVEQYKKELEK 265
Score = 34.3 bits (75), Expect = 0.50
Identities = 31/144 (21%), Positives = 62/144 (43%), Gaps = 1/144 (0%)
Frame = +2
Query: 128 DHLSNEKAAQEKIVKQLQHQLNEVQS-KADEANRTLNDLDAAKKKLSIENSDLLRQLEEA 304
D L +A E V+Q + +L + S K D A ++ + + + +L +
Sbjct: 243 DALQELRAQHEDQVEQYKKELEKTYSAKLDNARQSA---ERNSNLVGAAHEELQQSRIRI 299
Query: 305 ESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGK 484
+S +QLS+++ L + + L D ARER T E ++ +R +++++ +
Sbjct: 300 DSLSAQLSQLQKQLAAKEAKLRDLEDSLARERDTSRRLLAEKEREMAEMRARMQQQLDEY 359
Query: 485 ADLQRQLSKANAEAQLWRSKYESE 556
+L + E +R E E
Sbjct: 360 QELLDIKLALDMEIHAYRKLLEGE 383
>AL135927-2|CAI15521.1| 572|Homo sapiens lamin A/C protein.
Length = 572
Score = 58.0 bits (134), Expect = 4e-08
Identities = 48/200 (24%), Positives = 104/200 (52%), Gaps = 9/200 (4%)
Frame = +2
Query: 152 AQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSK 331
++E + +++ +++ +A +TL+ + + +L +E S + + +E +++ ++
Sbjct: 66 SEEVVSREVSGIKAAYEAELGDARKTLDSVAKERARLQLELSKVREEFKELKARNTKKEG 125
Query: 332 IKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVE--EEAEGKADLQRQ- 502
++ +L+D + L + + +T L + R LE +L ++R QV E A G+A Q Q
Sbjct: 126 DLIAAQARLKDLEALLNSKEAALSTALSEKRTLEGELHDLRGQVAKLEAALGEAKKQLQD 185
Query: 503 --LSKANAEAQLWRSKYESEGVAR--SEELEEAKRKLQARLAEAE--ETIESLNQKVVAL 664
L + +AE +L K E + SEEL E KR+ + RL E + + E ++ AL
Sbjct: 186 EMLRRVDAENRLQTMKEELDFQKNIYSEELRETKRRHETRLVEIDNGKQREFESRLADAL 245
Query: 665 EKTKQRLATEVEDLQLEVDR 724
++ + + +VE + E+++
Sbjct: 246 QELRAQHEDQVEQYKKELEK 265
Score = 34.3 bits (75), Expect = 0.50
Identities = 31/144 (21%), Positives = 62/144 (43%), Gaps = 1/144 (0%)
Frame = +2
Query: 128 DHLSNEKAAQEKIVKQLQHQLNEVQS-KADEANRTLNDLDAAKKKLSIENSDLLRQLEEA 304
D L +A E V+Q + +L + S K D A ++ + + + +L +
Sbjct: 243 DALQELRAQHEDQVEQYKKELEKTYSAKLDNARQSA---ERNSNLVGAAHEELQQSRIRI 299
Query: 305 ESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGK 484
+S +QLS+++ L + + L D ARER T E ++ +R +++++ +
Sbjct: 300 DSLSAQLSQLQKQLAAKEAKLRDLEDSLARERDTSRRLLAEKEREMAEMRARMQQQLDEY 359
Query: 485 ADLQRQLSKANAEAQLWRSKYESE 556
+L + E +R E E
Sbjct: 360 QELLDIKLALDMEIHAYRKLLEGE 383
>AL135927-1|CAI15520.1| 465|Homo sapiens lamin A/C protein.
Length = 465
Score = 58.0 bits (134), Expect = 4e-08
Identities = 48/200 (24%), Positives = 104/200 (52%), Gaps = 9/200 (4%)
Frame = +2
Query: 152 AQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSK 331
++E + +++ +++ +A +TL+ + + +L +E S + + +E +++ ++
Sbjct: 66 SEEVVSREVSGIKAAYEAELGDARKTLDSVAKERARLQLELSKVREEFKELKARNTKKEG 125
Query: 332 IKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVE--EEAEGKADLQRQ- 502
++ +L+D + L + + +T L + R LE +L ++R QV E A G+A Q Q
Sbjct: 126 DLIAAQARLKDLEALLNSKEAALSTALSEKRTLEGELHDLRGQVAKLEAALGEAKKQLQD 185
Query: 503 --LSKANAEAQLWRSKYESEGVAR--SEELEEAKRKLQARLAEAE--ETIESLNQKVVAL 664
L + +AE +L K E + SEEL E KR+ + RL E + + E ++ AL
Sbjct: 186 EMLRRVDAENRLQTMKEELDFQKNIYSEELRETKRRHETRLVEIDNGKQREFESRLADAL 245
Query: 665 EKTKQRLATEVEDLQLEVDR 724
++ + + +VE + E+++
Sbjct: 246 QELRAQHEDQVEQYKKELEK 265
Score = 34.3 bits (75), Expect = 0.50
Identities = 31/144 (21%), Positives = 62/144 (43%), Gaps = 1/144 (0%)
Frame = +2
Query: 128 DHLSNEKAAQEKIVKQLQHQLNEVQS-KADEANRTLNDLDAAKKKLSIENSDLLRQLEEA 304
D L +A E V+Q + +L + S K D A ++ + + + +L +
Sbjct: 243 DALQELRAQHEDQVEQYKKELEKTYSAKLDNARQSA---ERNSNLVGAAHEELQQSRIRI 299
Query: 305 ESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGK 484
+S +QLS+++ L + + L D ARER T E ++ +R +++++ +
Sbjct: 300 DSLSAQLSQLQKQLAAKEAKLRDLEDSLARERDTSRRLLAEKEREMAEMRARMQQQLDEY 359
Query: 485 ADLQRQLSKANAEAQLWRSKYESE 556
+L + E +R E E
Sbjct: 360 QELLDIKLALDMEIHAYRKLLEGE 383
>AK027863-1|BAB55415.1| 612|Homo sapiens protein ( Homo sapiens
cDNA FLJ14957 fis, clone PLACE4000009, weakly similar to
MYOSIN HEAVY CHAIN, NONMUSCLE TYPE B. ).
Length = 612
Score = 58.0 bits (134), Expect = 4e-08
Identities = 49/218 (22%), Positives = 98/218 (44%), Gaps = 1/218 (0%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+ D+ +L+ + LK + Q +V+ L L+ N + + + + Q+ ++
Sbjct: 352 LKDLEYELEAKSHLKDDRSRLVKQMEDKVSQLEMELEEERNNSDLLTERISRSREQMEQL 411
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAE-SQVSQLSKIKVSLTTQLEDTKRL 376
+++ + DL+ K L +N DL ++ E S S + V + ++ + +
Sbjct: 412 RNELLQERAARQDLECDKISLERQNKDLKSRIIHLEGSYRSSKEGLVVQMEARIAELEDR 471
Query: 377 ADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESE 556
+ E R+RA L R LE + + QV++E D + QLS + + + E E
Sbjct: 472 LESEERDRANLQLSNRRLERKVKELVMQVDDEHLSLTDQKDQLS---LRLKAMKRQVE-E 527
Query: 557 GVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEK 670
+ LE +K+KLQ L E + E L ++ +++K
Sbjct: 528 AEEEIDRLESSKKKLQRELEEQMDMNEHLQGQLNSMKK 565
Score = 51.6 bits (118), Expect = 3e-06
Identities = 52/236 (22%), Positives = 99/236 (41%), Gaps = 11/236 (4%)
Frame = +2
Query: 29 MGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSK 208
+ E D+L+ K ++ + E+ + L L K +E ++++ + +L ++
Sbjct: 17 LSEMHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIAKEGREDLLRKRERELTALKGA 76
Query: 209 A-DEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADE 385
+E + ++D K++ E L +EEA V L+ + T+
Sbjct: 77 LKEEVSSHDQEMDKLKEQYDAELQALRESVEEATKNVEVLASRSNTSEQDQAGTEMRVKL 136
Query: 386 EARERATLLGKFRNLEHDLDNIREQVEE----EAEGKADLQRQLSKANA--EAQLWRSKY 547
E L G+ LE + ++ Q+E+ EA+ K L++ + EA + K
Sbjct: 137 LQEENEKLQGRSEELERRVAQLQRQIEDLKGDEAKAKETLKKYEGEIRQLEEALVHVRKE 196
Query: 548 ESEGV----ARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVED 703
E E V A ELE A+ L E ++ E L ++ E+ + RL E+E+
Sbjct: 197 EKEAVSARRALENELEAAQGNLSQTTQEQKQLSEKLKEESEQKEQLR-RLKNEMEN 251
Score = 49.2 bits (112), Expect = 2e-05
Identities = 53/231 (22%), Positives = 106/231 (45%), Gaps = 2/231 (0%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD 214
E +QL++ K K + A+ ++ + + + ++ ++ +L + Q D
Sbjct: 280 ELQNQLDEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDGMRLMEEELRDYQRAQD 339
Query: 215 EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEAR 394
EA L+ K L E + L++ S++ + + KVS QLE + EE R
Sbjct: 340 EALTKRQLLEQTLKDLEYE-LEAKSHLKDDRSRLVKQMEDKVS---QLE----MELEEER 391
Query: 395 ERATLLG-KFRNLEHDLDNIREQVEEEAEGKADLQ-RQLSKANAEAQLWRSKYESEGVAR 568
+ LL + ++ +R ++ +E + DL+ ++S L EG R
Sbjct: 392 NNSDLLTERISRSREQMEQLRNELLQERAARQDLECDKISLERQNKDLKSRIIHLEGSYR 451
Query: 569 SEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
S + E +++AR+AE E+ +ES + L+ + +RL +V++L ++VD
Sbjct: 452 SSK-EGLVVQMEARIAELEDRLESEERDRANLQLSNRRLERKVKELVMQVD 501
Score = 35.1 bits (77), Expect = 0.29
Identities = 30/91 (32%), Positives = 42/91 (46%)
Frame = +2
Query: 452 REQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEET 631
REQ + E DLQ QLS+ + E + + E A EEL +AK+ LQ L E
Sbjct: 3 REQHQTEIR---DLQDQLSEMHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIAKEGR 59
Query: 632 IESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
+ L ++ L K L EV E+D+
Sbjct: 60 EDLLRKRERELTALKGALKEEVSSHDQEMDK 90
>X75304-1|CAA53052.1| 3259|Homo sapiens giantin protein.
Length = 3259
Score = 57.6 bits (133), Expect = 5e-08
Identities = 50/243 (20%), Positives = 115/243 (47%), Gaps = 11/243 (4%)
Frame = +2
Query: 29 MGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSK 208
+ + L +L++ E ++Q + DL L+ + EK +EK K +Q +L+ ++ +
Sbjct: 2095 LADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQ-AEEKHLKEK--KNMQEKLDALRRE 2151
Query: 209 ADEANRTLNDLDAAKKKLSIENSDLLRQLEE-AESQVSQLSKIKVSLTTQLEDTKRLADE 385
T+ ++ K E ++QL+E +S V+QL+ S+++ +D R+ DE
Sbjct: 2152 KVHLEETIGEIQVTLNKKDKE----VQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVIDE 2207
Query: 386 EARERATLLGKFRNLEHDL----DN---IREQVEEEAEGKADLQRQLSKANAEAQLWRSK 544
+ ++ E ++ DN +++Q+ + + +L+ +S+ + Q+W SK
Sbjct: 2208 AKKWERKFSDAIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELKINISRLEHDKQIWESK 2267
Query: 545 YESEGVARS---EELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLE 715
++E + + L+ ++L ++L E S ++ LE + L ++ DL
Sbjct: 2268 AQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNS 2327
Query: 716 VDR 724
+++
Sbjct: 2328 LEK 2330
Score = 54.0 bits (124), Expect = 6e-07
Identities = 44/200 (22%), Positives = 90/200 (45%), Gaps = 2/200 (1%)
Frame = +2
Query: 104 VNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAA--KKKLSIENS 277
+ L++ L + +E + V+ + ++ E+ + + +D +KK +E
Sbjct: 833 IRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVET- 891
Query: 278 DLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIRE 457
L + +EE + QV+++S QL + K E + TL + L + +E
Sbjct: 892 -LQQTIEEKDQQVTEISFSMTEKMVQLNEEKFSLGVEIK---TLKEQLNLLSRAEEAKKE 947
Query: 458 QVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIE 637
QVEE+ E + L++ + + Q+ + + + E +E E+ KRKLQA L +E ++
Sbjct: 948 QVEEDNEVSSGLKQNYDEMSPAGQISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQ 1007
Query: 638 SLNQKVVALEKTKQRLATEV 697
+++ L K E+
Sbjct: 1008 RVSRLEEELANLKDESKKEI 1027
Score = 53.2 bits (122), Expect = 1e-06
Identities = 52/228 (22%), Positives = 103/228 (45%)
Frame = +2
Query: 26 DMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQS 205
++ +LD+L KL +K E+ + ++++ A L + E QE ++K L QL E+Q+
Sbjct: 1389 ELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQL-EMQA 1447
Query: 206 KADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADE 385
K + D K+L +E L ++++ ++ + S+ K + +L+ E
Sbjct: 1448 K---------EHDERIKQLQVE----LCEMKQKPEEIGEESRAKQQIQRKLQAALISRKE 1494
Query: 386 EARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVA 565
+E ++L+ +L R +E + AD++ Q+S N E +
Sbjct: 1495 ALKEN-------KSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEE 1547
Query: 566 RSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQ 709
R + + E R L + + ESL + L + K++L E+E L+
Sbjct: 1548 RDKLITEMDRSLLENQS-LSSSCESLKLALEGLTEDKEKLVKEIESLK 1594
Score = 49.6 bits (113), Expect = 1e-05
Identities = 50/219 (22%), Positives = 95/219 (43%), Gaps = 5/219 (2%)
Frame = +2
Query: 83 RAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKL 262
R Q+ E+ +L L E E+ K+ + N++ + A
Sbjct: 2403 RQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDSF 2462
Query: 263 SIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDL 442
S L + QL + +S+ + + +L E A E L + R L +
Sbjct: 2463 VKSMSSLQNDRDRIVGDYQQLEERHLSIILEKD---QLIQEAAAENNKLKEEIRGLRSHM 2519
Query: 443 DNIR-EQVEEEAE---GKADLQRQLS-KANAEAQLWRSKYESEGVARSEELEEAKRKLQA 607
D++ E + +AE + DL + ++ K + + QL + + +++ELE KL+
Sbjct: 2520 DDLNSENAKLDAELIQYREDLNQVITIKDSQQKQLLEVQLQ-----QNKELENKYAKLEE 2574
Query: 608 RLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
+L E+EE E L + AL++ KQ L+ E+E L++ + +
Sbjct: 2575 KLKESEEANEDLRRSFNALQEEKQDLSKEIESLKVSISQ 2613
Score = 40.7 bits (91), Expect = 0.006
Identities = 51/233 (21%), Positives = 101/233 (43%), Gaps = 7/233 (3%)
Frame = +2
Query: 26 DMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQS 205
D + + ++ LK+ ++ + +L+ + L +++QH + V+
Sbjct: 1582 DKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQ 1641
Query: 206 KADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADE 385
+ E L +A KK+ +QL+EAE ++ ++ K K+ + + K L E
Sbjct: 1642 EKQELYGKLRSTEANKKETE-------KQLQEAEQEMEEM-KEKMRKFAKSKQQKILELE 1693
Query: 386 EARERATLLGKFRNLEHDL-DNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYE---S 553
E +R R H D +E +E A ++ +L + E + K++ S
Sbjct: 1694 EENDR------LRAEVHPAGDTAKECMETLLSSNASMKEELERVKMEYETLSKKFQSLMS 1747
Query: 554 EGVARSEELEEAKRKLQ---ARLAEAEETIESLNQKVVALEKTKQRLATEVED 703
E + SEE+++ K +++ ++ A E T + NQ V E T Q + E E+
Sbjct: 1748 EKDSLSEEVQDLKHQIEDNVSKQANLEATEKHDNQTNVTEEGT-QSIPGETEE 1799
Score = 39.5 bits (88), Expect = 0.013
Identities = 51/243 (20%), Positives = 101/243 (41%), Gaps = 16/243 (6%)
Frame = +2
Query: 44 DQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADE-- 217
DQL ++ E+ + +D + E Q+K+ LQ + E+ S+ +E
Sbjct: 2238 DQLRQMSIHMEELKINISRLEHDKQIWESKAQTEVQLQQKVCDTLQGENKELLSQLEETR 2297
Query: 218 -----ANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLAD 382
+ L L++ K L + +DL LE+ + Q L I ++++K +
Sbjct: 2298 HLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSK-FSY 2356
Query: 383 EEARERATLLGKFRNLEHDLDNIREQV-------EEEA--EGKADLQRQLSKANAEAQLW 535
E+ + + H+ N++EQ +EEA A+L++Q K E +
Sbjct: 2357 EQLETDLQASRELTSRLHEEINMKEQKIISLLSGKEEAIQVAIAELRQQHDKEIKELENL 2416
Query: 536 RSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLE 715
S+ E E + LEE +K + + ET++++ ++ + + + LQ +
Sbjct: 2417 LSQEEEENIV----LEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQND 2472
Query: 716 VDR 724
DR
Sbjct: 2473 RDR 2475
Score = 39.1 bits (87), Expect = 0.018
Identities = 56/238 (23%), Positives = 109/238 (45%), Gaps = 16/238 (6%)
Frame = +2
Query: 35 EQLDQLNKLKA--KAEKXRAQYFSEV--NDLRAGLDHLSNE----KAAQEKIVK------ 172
+Q+DQL + A + EK + + FS+ N+ L +S + K QE++ K
Sbjct: 1840 QQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQ 1899
Query: 173 QLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTT 352
Q+Q +L+ V + A +DL+ ++L + ++L + V+ L +
Sbjct: 1900 QIQEELSRVTKLKETAEEEKDDLE---ERLMNQLAELNGSIGNYCQDVTDAQIKNELLES 1956
Query: 353 QLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQL 532
++++ K+ E E+ L+ + +E + IR++ E+ +G S A +L
Sbjct: 1957 EMKNLKKCVSELEEEKQQLVKEKTKVESE---IRKEYLEKIQGAQKEPGNKSHAKELQEL 2013
Query: 533 WRSKYESEGVARSEELEEAKRKLQA--RLAEAEETIESLNQKVVALEKTKQRLATEVE 700
+ K + E ++ + K+ A R +A E +++ +QK LE TK+ LA VE
Sbjct: 2014 LKEK-QQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQK--DLEITKENLAQAVE 2068
Score = 38.3 bits (85), Expect = 0.031
Identities = 59/231 (25%), Positives = 99/231 (42%), Gaps = 21/231 (9%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV--QSK 208
+Q +L AK E+ + DLR + L EK K ++ L+ ++++ Q
Sbjct: 2560 QQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSKEIESLKVSISQLTRQVT 2619
Query: 209 ADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEE 388
A + TL A K E L ++ ++++L + V + Q E K++ + E
Sbjct: 2620 ALQEEGTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELVCV--QKEAAKKVGEIE 2677
Query: 389 ARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQL----------SKAN----AEA 526
+ + L ++L HD +R + E E A+L R L +K N A+
Sbjct: 2678 DKLKKEL----KHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKGLTAQI 2733
Query: 527 QLWRSKYESEGVAR---SEELEEAKRKLQARLAEAEETIES--LNQKVVAL 664
Q + S +R +EEL+E KRK A L E + E LN++ AL
Sbjct: 2734 QSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKEQGLLNRERDAL 2784
Score = 37.1 bits (82), Expect = 0.071
Identities = 51/226 (22%), Positives = 101/226 (44%), Gaps = 25/226 (11%)
Frame = +2
Query: 101 EVNDLRAGLDHLSNEKAA-QEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENS 277
E+ L+ + L+ + A QE+ L H +++ K +E +R +++K+++
Sbjct: 2603 EIESLKVSISQLTRQVTALQEEGTLGLYHA--QLKVKEEEVHRLSALFSSSQKRIAELEE 2660
Query: 278 DLLRQLEEAESQVSQLS-KIKVSLTTQLEDT--KRLADEEARERATLLGK-FRNLEHDL- 442
+L+ +EA +V ++ K+K L D R E A ER L + +E L
Sbjct: 2661 ELVCVQKEAAKKVGEIEDKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLL 2720
Query: 443 ------DNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYES--EGVARSEELEEAKRK 598
+ Q++ + LQ AN E + KY++ + +A+ +E R+
Sbjct: 2721 MVTKENKGLTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKEQGLLNRE 2780
Query: 599 LQARLAEA-------EET----IESLNQKVVALEKTKQRLATEVED 703
A L+E EE +E LNQ++++ ++ L++++ED
Sbjct: 2781 RDALLSETAFSMNSTEENSLSHLEKLNQQLLSKDEQLLHLSSQLED 2826
Score = 36.7 bits (81), Expect = 0.094
Identities = 39/145 (26%), Positives = 67/145 (46%), Gaps = 3/145 (2%)
Frame = +2
Query: 278 DLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFR-NLEHDLDNIR 454
D+ +L AE V +L I QL+ EE + + K + + + L ++
Sbjct: 49 DVQERLAYAEQLVVELKDIIRQKDVQLQQKDEALQEERKAADNKIKKLKLHAKAKLTSLN 108
Query: 455 EQVEE-EAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEET 631
+ +EE +A+G L ++ +E QL SK++ E+E+ K KLQ E EE
Sbjct: 109 KYIEEMKAQGGTVLP---TEPQSEEQL--SKHDKSSTEEEMEIEKIKHKLQ----EKEEL 159
Query: 632 IESLN-QKVVALEKTKQRLATEVED 703
I +L Q A + + +TE+E+
Sbjct: 160 ISTLQAQLTQAQAEQPAQSSTEMEE 184
>M97501-1|AAA35693.1| 1392|Homo sapiens cytoplasmic linker protein-170
alpha-2 protein.
Length = 1392
Score = 57.6 bits (133), Expect = 5e-08
Identities = 52/230 (22%), Positives = 110/230 (47%), Gaps = 4/230 (1%)
Frame = +2
Query: 41 LDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKA---AQEKIVKQLQHQL-NEVQSK 208
L +L +L+ +AEK +A +E D ++ ++ EK A + KQ +L NE+ +
Sbjct: 1023 LQELEELRKQAEKAKAAQTAE--DAMQIMEQMTKEKTETLASLEDTKQTNAKLQNELDTL 1080
Query: 209 ADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEE 388
+ + + +L+ +K+ L++EN + +E E+ ++ L+ E+ +LA+E
Sbjct: 1081 KENNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQAAAQKSQQLSALQEENVKLAEEL 1140
Query: 389 ARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVAR 568
R R + + LE + + Q+ E + ++ + + A Q S + +
Sbjct: 1141 GRSRDEVT-SHQKLEEERSVLNNQLLEMKKRESKFIKDADEEKASLQKSISITSALLTEK 1199
Query: 569 SEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEV 718
ELE+ + ++ E + +SL+ V LE K +L +V++L+L++
Sbjct: 1200 DAELEKLRNEVTVLRGE-NASAKSLHSVVQTLESDKVKLELKVKNLELQL 1248
Score = 51.6 bits (118), Expect = 3e-06
Identities = 51/251 (20%), Positives = 116/251 (46%), Gaps = 24/251 (9%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVK--QLQHQLN 193
++++ E L +++++K EK Q E A + +S +++ QE + K Q + Q N
Sbjct: 786 LTNLQENLSEVSQVKETLEK-ELQILKE-KFAEASEEAVSVQRSMQETVNKLHQKEEQFN 843
Query: 194 EVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIK---VSLTTQLED 364
+ S ++ L D++A ++ L++ E+ E+ ++++ K+ S T++ D
Sbjct: 844 MLSSDLEKLRENLADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMND 903
Query: 365 TKRLADEEARERATLLGKFRN----LEHDLDNIR---EQVEEEAEGK------------A 487
RL + + E L K L+ ++++ EQ ++EA K +
Sbjct: 904 ELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLS 963
Query: 488 DLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALE 667
DL++++ ++ + Q +++YE + EE + LQ L + E+ ++ ++ L
Sbjct: 964 DLEKKMETSHNQCQELKARYERATSETKTKHEEILQNLQKTLLDTEDKLKGAREENSGLL 1023
Query: 668 KTKQRLATEVE 700
+ + L + E
Sbjct: 1024 QELEELRKQAE 1034
Score = 47.2 bits (107), Expect = 7e-05
Identities = 57/253 (22%), Positives = 117/253 (46%), Gaps = 25/253 (9%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKA-EKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNE 196
+ DM + +Q + AK E+ + + +++DL ++ N+ QE + + + +E
Sbjct: 933 IEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQ--CQE-LKARYERATSE 989
Query: 197 VQSKADEA----NRTLNDLDAAKKKLSIENSDLLRQLEEAESQ----------------V 316
++K +E +TL D + K ENS LL++LEE Q +
Sbjct: 990 TKTKHEEILQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQAEKAKAAQTAEDAMQIM 1049
Query: 317 SQLSKIKVSLTTQLEDTKRLADEEARERATLL-GKFRNLEHDLDNIREQVEEEAEGKADL 493
Q++K K LEDTK+ + E TL +N+E +L+ +E + E + +
Sbjct: 1050 EQMTKEKTETLASLEDTKQTNAKLQNELDTLKENNLKNVE-ELNKSKELLTVENQKMEEF 1108
Query: 494 QRQ---LSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVAL 664
+++ L +A A+ S + E V +EEL ++ ++ + + EE LN +++ +
Sbjct: 1109 RKEIETLKQAAAQKSQQLSALQEENVKLAEELGRSRDEVTSH-QKLEEERSVLNNQLLEM 1167
Query: 665 EKTKQRLATEVED 703
+K + + + ++
Sbjct: 1168 KKRESKFIKDADE 1180
Score = 45.6 bits (103), Expect = 2e-04
Identities = 41/204 (20%), Positives = 84/204 (41%), Gaps = 1/204 (0%)
Frame = +2
Query: 116 RAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQL 295
++ + L + A EK +K L+ + N SKA R L + L S++ +
Sbjct: 741 KSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVK 800
Query: 296 EEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEE-E 472
E E ++ L + + + +R E + +F L DL+ +RE + + E
Sbjct: 801 ETLEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADME 860
Query: 473 AEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQK 652
A+ + +R+ A+ +L E ++ + K + RL E + +E L K
Sbjct: 861 AKFREKDEREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERD--VEELQLK 918
Query: 653 VVALEKTKQRLATEVEDLQLEVDR 724
+ + L +ED+ ++ ++
Sbjct: 919 LTKANENASFLQKSIEDMTVKAEQ 942
Score = 38.7 bits (86), Expect = 0.023
Identities = 61/265 (23%), Positives = 117/265 (44%), Gaps = 32/265 (12%)
Frame = +2
Query: 23 SDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSN--EKAAQEKI--VKQLQHQ- 187
+++ + + +++ + R + V +L A +D L E A +EK+ + QL+ +
Sbjct: 376 AEVAKATSHVGEIEQELALARDGHDQHVLELEAKMDQLRTMVEAADREKVELLNQLEEEK 435
Query: 188 --LNEVQSKADEANRTLNDLDAA-----------KKKLSI---ENSDLLRQLE------E 301
+ ++Q + +E + T DL+ A +K L++ E ++L R+LE +
Sbjct: 436 RKVEDLQFRVEEESITKGDLEVATVSEKSRIMELEKDLALRVQEVAELRRRLESNKPAGD 495
Query: 302 AESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLG-KFRNLEHDLDNIREQVEEEAE 478
+ +S L +I SL +LE T+ E G + + ++ + E+ ++
Sbjct: 496 VDMSLSLLQEIS-SLQEKLEVTRTDHQREITSLKEHFGAREETHQKEIKALYTATEKLSK 554
Query: 479 GKADLQRQLSKANAEAQ----LWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLN 646
L+ +L AN E LW+SK E+ + + +EE K L ET E
Sbjct: 555 ENESLKSKLEHANKENSDVIALWKSKLETAIASHQQAMEELKVSFSKGL--GTETAEFAE 612
Query: 647 QKVVALEKTKQRLATEVEDLQLEVD 721
K +EK + E+E+LQ + D
Sbjct: 613 LK-TQIEKMRLDYQHEIENLQNQQD 636
Score = 37.1 bits (82), Expect = 0.071
Identities = 36/176 (20%), Positives = 86/176 (48%), Gaps = 3/176 (1%)
Frame = +2
Query: 176 LQHQLNEVQSKADE--ANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLT 349
LQ L E Q ++ A R L + AK + ++ ++L A Q + L
Sbjct: 353 LQEALKEKQQHIEQLLAERDLERAEVAKATSHV--GEIEQELALARDGHDQHV---LELE 407
Query: 350 TQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQ 529
+++ + + + RE+ LL + + +++++ +VEEE+ K DL +++ + +++
Sbjct: 408 AKMDQLRTMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDL--EVATVSEKSR 465
Query: 530 LWRSKYESEGVARSEELEEAKRKLQARLAEAEETIE-SLNQKVVALEKTKQRLATE 694
+ + E + R +E+ E +R+L++ + + SL Q++ +L++ + T+
Sbjct: 466 I--MELEKDLALRVQEVAELRRRLESNKPAGDVDMSLSLLQEISSLQEKLEVTRTD 519
>D25542-1|BAA05025.1| 3225|Homo sapiens golgi antigen gcp372 protein.
Length = 3225
Score = 57.6 bits (133), Expect = 5e-08
Identities = 50/243 (20%), Positives = 115/243 (47%), Gaps = 11/243 (4%)
Frame = +2
Query: 29 MGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSK 208
+ + L +L++ E ++Q + DL L+ + EK +EK K +Q +L+ ++ +
Sbjct: 2061 LADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQ-AEEKHLKEK--KNMQEKLDALRRE 2117
Query: 209 ADEANRTLNDLDAAKKKLSIENSDLLRQLEE-AESQVSQLSKIKVSLTTQLEDTKRLADE 385
T+ ++ K E ++QL+E +S V+QL+ S+++ +D R+ DE
Sbjct: 2118 KVHLEETIGEIQVTLNKKDKE----VQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVIDE 2173
Query: 386 EARERATLLGKFRNLEHDL----DN---IREQVEEEAEGKADLQRQLSKANAEAQLWRSK 544
+ ++ E ++ DN +++Q+ + + +L+ +S+ + Q+W SK
Sbjct: 2174 AKKWERKFSDAIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELKINISRLEHDKQIWESK 2233
Query: 545 YESEGVARS---EELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLE 715
++E + + L+ ++L ++L E S ++ LE + L ++ DL
Sbjct: 2234 AQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNS 2293
Query: 716 VDR 724
+++
Sbjct: 2294 LEK 2296
Score = 54.0 bits (124), Expect = 6e-07
Identities = 44/200 (22%), Positives = 90/200 (45%), Gaps = 2/200 (1%)
Frame = +2
Query: 104 VNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAA--KKKLSIENS 277
+ L++ L + +E + V+ + ++ E+ + + +D +KK +E
Sbjct: 799 IRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVET- 857
Query: 278 DLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIRE 457
L + +EE + QV+++S QL + K E + TL + L + +E
Sbjct: 858 -LQQTIEEKDQQVTEISFSMTEKMVQLNEEKFSLGVEIK---TLKEQLNLLSRAEEAKKE 913
Query: 458 QVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIE 637
QVEE+ E + L++ + + Q+ + + + E +E E+ KRKLQA L +E ++
Sbjct: 914 QVEEDNEVSSGLKQNYDEMSPAGQISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQ 973
Query: 638 SLNQKVVALEKTKQRLATEV 697
+++ L K E+
Sbjct: 974 RVSRLEEELANLKDESKKEI 993
Score = 53.2 bits (122), Expect = 1e-06
Identities = 52/228 (22%), Positives = 103/228 (45%)
Frame = +2
Query: 26 DMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQS 205
++ +LD+L KL +K E+ + ++++ A L + E QE ++K L QL E+Q+
Sbjct: 1355 ELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQL-EMQA 1413
Query: 206 KADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADE 385
K + D K+L +E L ++++ ++ + S+ K + +L+ E
Sbjct: 1414 K---------EHDERIKQLQVE----LCEMKQKPEEIGEESRAKQQIQRKLQAALISRKE 1460
Query: 386 EARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVA 565
+E ++L+ +L R +E + AD++ Q+S N E +
Sbjct: 1461 ALKEN-------KSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEE 1513
Query: 566 RSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQ 709
R + + E R L + + ESL + L + K++L E+E L+
Sbjct: 1514 RDKLITEMDRSLLENQS-LSSSCESLKLALEGLTEDKEKLVKEIESLK 1560
Score = 49.6 bits (113), Expect = 1e-05
Identities = 50/219 (22%), Positives = 95/219 (43%), Gaps = 5/219 (2%)
Frame = +2
Query: 83 RAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKL 262
R Q+ E+ +L L E E+ K+ + N++ + A
Sbjct: 2369 RQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDSF 2428
Query: 263 SIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDL 442
S L + QL + +S+ + + +L E A E L + R L +
Sbjct: 2429 VKSMSSLQNDRDRIVGDYQQLEERHLSIILEKD---QLIQEAAAENNKLKEEIRGLRSHM 2485
Query: 443 DNIR-EQVEEEAE---GKADLQRQLS-KANAEAQLWRSKYESEGVARSEELEEAKRKLQA 607
D++ E + +AE + DL + ++ K + + QL + + +++ELE KL+
Sbjct: 2486 DDLNSENAKLDAELIQYREDLNQVITIKDSQQKQLLEVQLQ-----QNKELENKYAKLEE 2540
Query: 608 RLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
+L E+EE E L + AL++ KQ L+ E+E L++ + +
Sbjct: 2541 KLKESEEANEDLRRSFNALQEEKQDLSKEIESLKVSISQ 2579
Score = 40.7 bits (91), Expect = 0.006
Identities = 51/233 (21%), Positives = 101/233 (43%), Gaps = 7/233 (3%)
Frame = +2
Query: 26 DMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQS 205
D + + ++ LK+ ++ + +L+ + L +++QH + V+
Sbjct: 1548 DKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQ 1607
Query: 206 KADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADE 385
+ E L +A KK+ +QL+EAE ++ ++ K K+ + + K L E
Sbjct: 1608 EKQELYGKLRSTEANKKETE-------KQLQEAEQEMEEM-KEKMRKFAKSKQQKILELE 1659
Query: 386 EARERATLLGKFRNLEHDL-DNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYE---S 553
E +R R H D +E +E A ++ +L + E + K++ S
Sbjct: 1660 EENDR------LRAEVHPAGDTAKECMETLLSSNASMKEELERVKMEYETLSKKFQSLMS 1713
Query: 554 EGVARSEELEEAKRKLQ---ARLAEAEETIESLNQKVVALEKTKQRLATEVED 703
E + SEE+++ K +++ ++ A E T + NQ V E T Q + E E+
Sbjct: 1714 EKDSLSEEVQDLKHQIEGNVSKQANLEATEKHDNQTNVTEEGT-QSIPGETEE 1765
Score = 39.5 bits (88), Expect = 0.013
Identities = 51/243 (20%), Positives = 101/243 (41%), Gaps = 16/243 (6%)
Frame = +2
Query: 44 DQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADE-- 217
DQL ++ E+ + +D + E Q+K+ LQ + E+ S+ +E
Sbjct: 2204 DQLRQMSIHMEELKINISRLEHDKQIWESKAQTEVQLQQKVCDTLQGENKELLSQLEETR 2263
Query: 218 -----ANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLAD 382
+ L L++ K L + +DL LE+ + Q L I ++++K +
Sbjct: 2264 HLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSK-FSY 2322
Query: 383 EEARERATLLGKFRNLEHDLDNIREQV-------EEEA--EGKADLQRQLSKANAEAQLW 535
E+ + + H+ N++EQ +EEA A+L++Q K E +
Sbjct: 2323 EQLETDLQASRELTSRLHEEINMKEQKIISLLSGKEEAIQVAIAELRQQHDKEIKELENL 2382
Query: 536 RSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLE 715
S+ E E + LEE +K + + ET++++ ++ + + + LQ +
Sbjct: 2383 LSQEEEENIV----LEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQND 2438
Query: 716 VDR 724
DR
Sbjct: 2439 RDR 2441
Score = 39.1 bits (87), Expect = 0.018
Identities = 56/238 (23%), Positives = 109/238 (45%), Gaps = 16/238 (6%)
Frame = +2
Query: 35 EQLDQLNKLKA--KAEKXRAQYFSEV--NDLRAGLDHLSNE----KAAQEKIVK------ 172
+Q+DQL + A + EK + + FS+ N+ L +S + K QE++ K
Sbjct: 1806 QQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQ 1865
Query: 173 QLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTT 352
Q+Q +L+ V + A +DL+ ++L + ++L + V+ L +
Sbjct: 1866 QIQEELSRVTKLKETAEEEKDDLE---ERLMNQLAELNGSIGNYCQDVTDAQIKNELLES 1922
Query: 353 QLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQL 532
++++ K+ E E+ L+ + +E + IR++ E+ +G S A +L
Sbjct: 1923 EMKNLKKCVSELEEEKQQLVKEKTKVESE---IRKEYLEKIQGAQKEPGNKSHAKELQEL 1979
Query: 533 WRSKYESEGVARSEELEEAKRKLQA--RLAEAEETIESLNQKVVALEKTKQRLATEVE 700
+ K + E ++ + K+ A R +A E +++ +QK LE TK+ LA VE
Sbjct: 1980 LKEK-QQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQK--DLEITKENLAQAVE 2034
Score = 38.3 bits (85), Expect = 0.031
Identities = 59/231 (25%), Positives = 99/231 (42%), Gaps = 21/231 (9%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV--QSK 208
+Q +L AK E+ + DLR + L EK K ++ L+ ++++ Q
Sbjct: 2526 QQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSKEIESLKVSISQLTRQVT 2585
Query: 209 ADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEE 388
A + TL A K E L ++ ++++L + V + Q E K++ + E
Sbjct: 2586 ALQEEGTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELVCV--QKEAAKKVGEIE 2643
Query: 389 ARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQL----------SKAN----AEA 526
+ + L ++L HD +R + E E A+L R L +K N A+
Sbjct: 2644 DKLKKEL----KHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKGLTAQI 2699
Query: 527 QLWRSKYESEGVAR---SEELEEAKRKLQARLAEAEETIES--LNQKVVAL 664
Q + S +R +EEL+E KRK A L E + E LN++ AL
Sbjct: 2700 QSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKEQGLLNRERDAL 2750
Score = 37.1 bits (82), Expect = 0.071
Identities = 51/226 (22%), Positives = 101/226 (44%), Gaps = 25/226 (11%)
Frame = +2
Query: 101 EVNDLRAGLDHLSNEKAA-QEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENS 277
E+ L+ + L+ + A QE+ L H +++ K +E +R +++K+++
Sbjct: 2569 EIESLKVSISQLTRQVTALQEEGTLGLYHA--QLKVKEEEVHRLSALFSSSQKRIAELEE 2626
Query: 278 DLLRQLEEAESQVSQLS-KIKVSLTTQLEDT--KRLADEEARERATLLGK-FRNLEHDL- 442
+L+ +EA +V ++ K+K L D R E A ER L + +E L
Sbjct: 2627 ELVCVQKEAAKKVGEIEDKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLL 2686
Query: 443 ------DNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYES--EGVARSEELEEAKRK 598
+ Q++ + LQ AN E + KY++ + +A+ +E R+
Sbjct: 2687 MVTKENKGLTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKEQGLLNRE 2746
Query: 599 LQARLAEA-------EET----IESLNQKVVALEKTKQRLATEVED 703
A L+E EE +E LNQ++++ ++ L++++ED
Sbjct: 2747 RDALLSETAFSMNSTEENSLSHLEKLNQQLLSKDEQLLHLSSQLED 2792
Score = 36.7 bits (81), Expect = 0.094
Identities = 39/145 (26%), Positives = 67/145 (46%), Gaps = 3/145 (2%)
Frame = +2
Query: 278 DLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFR-NLEHDLDNIR 454
D+ +L AE V +L I QL+ EE + + K + + + L ++
Sbjct: 10 DVQERLAYAEQLVVELKDIIRQKDVQLQQKDEALQEERKAADNKIKKLKLHAKAKLTSLN 69
Query: 455 EQVEE-EAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEET 631
+ +EE +A+G L ++ +E QL SK++ E+E+ K KLQ E EE
Sbjct: 70 KYIEEMKAQGGTVLP---TEPQSEEQL--SKHDKSSTEEEMEIEKIKHKLQ----EKEEL 120
Query: 632 IESLN-QKVVALEKTKQRLATEVED 703
I +L Q A + + +TE+E+
Sbjct: 121 ISTLQAQLTQAQAEQPAQSSTEMEE 145
>BC117209-1|AAI17210.1| 1438|Homo sapiens CLIP1 protein protein.
Length = 1438
Score = 57.6 bits (133), Expect = 5e-08
Identities = 52/230 (22%), Positives = 110/230 (47%), Gaps = 4/230 (1%)
Frame = +2
Query: 41 LDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKA---AQEKIVKQLQHQL-NEVQSK 208
L +L +L+ +AEK +A +E D ++ ++ EK A + KQ +L NE+ +
Sbjct: 1069 LQELEELRKQAEKAKAAQTAE--DAMQIMEQMTKEKTETLASLEDTKQTNAKLQNELDTL 1126
Query: 209 ADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEE 388
+ + + +L+ +K+ L++EN + +E E+ ++ L+ E+ +LA+E
Sbjct: 1127 KENNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQAAAQKSQQLSALQEENVKLAEEL 1186
Query: 389 ARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVAR 568
R R + + LE + + Q+ E + ++ + + A Q S + +
Sbjct: 1187 GRSRDEVT-SHQKLEEERSVLNNQLLEMKKRESKFIKDADEEKASLQKSISITSALLTEK 1245
Query: 569 SEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEV 718
ELE+ + ++ E + +SL+ V LE K +L +V++L+L++
Sbjct: 1246 DAELEKLRNEVTVLRGE-NASAKSLHSVVQTLESDKVKLELKVKNLELQL 1294
Score = 51.6 bits (118), Expect = 3e-06
Identities = 51/251 (20%), Positives = 116/251 (46%), Gaps = 24/251 (9%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVK--QLQHQLN 193
++++ E L +++++K EK Q E A + +S +++ QE + K Q + Q N
Sbjct: 832 LTNLQENLSEVSQVKETLEK-ELQILKE-KFAEASEEAVSVQRSMQETVNKLHQKEEQFN 889
Query: 194 EVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIK---VSLTTQLED 364
+ S ++ L D++A ++ L++ E+ E+ ++++ K+ S T++ D
Sbjct: 890 MLSSDLEKLRENLADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSGDNPSQLTKMND 949
Query: 365 TKRLADEEARERATLLGKFRN----LEHDLDNIR---EQVEEEAEGK------------A 487
RL + + E L K L+ ++++ EQ ++EA K +
Sbjct: 950 ELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLS 1009
Query: 488 DLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALE 667
DL++++ ++ + Q +++YE + EE + LQ L + E+ ++ ++ L
Sbjct: 1010 DLEKKMETSHNQCQELKARYERATSETKTKHEEILQNLQKTLLDTEDKLKGAREENSGLL 1069
Query: 668 KTKQRLATEVE 700
+ + L + E
Sbjct: 1070 QELEELRKQAE 1080
Score = 47.2 bits (107), Expect = 7e-05
Identities = 57/253 (22%), Positives = 117/253 (46%), Gaps = 25/253 (9%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKA-EKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNE 196
+ DM + +Q + AK E+ + + +++DL ++ N+ QE + + + +E
Sbjct: 979 IEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQ--CQE-LKARYERATSE 1035
Query: 197 VQSKADEA----NRTLNDLDAAKKKLSIENSDLLRQLEEAESQ----------------V 316
++K +E +TL D + K ENS LL++LEE Q +
Sbjct: 1036 TKTKHEEILQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQAEKAKAAQTAEDAMQIM 1095
Query: 317 SQLSKIKVSLTTQLEDTKRLADEEARERATLL-GKFRNLEHDLDNIREQVEEEAEGKADL 493
Q++K K LEDTK+ + E TL +N+E +L+ +E + E + +
Sbjct: 1096 EQMTKEKTETLASLEDTKQTNAKLQNELDTLKENNLKNVE-ELNKSKELLTVENQKMEEF 1154
Query: 494 QRQ---LSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVAL 664
+++ L +A A+ S + E V +EEL ++ ++ + + EE LN +++ +
Sbjct: 1155 RKEIETLKQAAAQKSQQLSALQEENVKLAEELGRSRDEVTSH-QKLEEERSVLNNQLLEM 1213
Query: 665 EKTKQRLATEVED 703
+K + + + ++
Sbjct: 1214 KKRESKFIKDADE 1226
Score = 45.2 bits (102), Expect = 3e-04
Identities = 41/204 (20%), Positives = 84/204 (41%), Gaps = 1/204 (0%)
Frame = +2
Query: 116 RAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQL 295
++ + L + A EK +K L+ + N SKA R L + L S++ +
Sbjct: 787 KSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVK 846
Query: 296 EEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEE-E 472
E E ++ L + + + +R E + +F L DL+ +RE + + E
Sbjct: 847 ETLEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADME 906
Query: 473 AEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQK 652
A+ + +R+ A+ +L E ++ + K + RL E + +E L K
Sbjct: 907 AKFREKDEREEQLIKAKEKLENDIAEIMKMSGDNPSQLTKMNDELRLKERD--VEELQLK 964
Query: 653 VVALEKTKQRLATEVEDLQLEVDR 724
+ + L +ED+ ++ ++
Sbjct: 965 LTKANENASFLQKSIEDMTVKAEQ 988
Score = 43.2 bits (97), Expect = 0.001
Identities = 43/188 (22%), Positives = 86/188 (45%), Gaps = 6/188 (3%)
Frame = +2
Query: 176 LQHQLNEVQSKADE--ANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLT 349
LQ L E Q ++ A R L + AK + ++ ++L A Q + L
Sbjct: 353 LQEALKEKQQHIEQLLAERDLERAEVAKATSHV--GEIEQELALARDGHDQHV---LELE 407
Query: 350 TQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQ 529
+++ + + + RE+ LL + + +++++ +VEEE+ K DL+ Q S+ + + +
Sbjct: 408 AKMDQLRTMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLE-QKSQISEDPE 466
Query: 530 LWRSKYESEGVARSEE---LEEAKR-KLQARLAEAEETIESLNQKVVALEKTKQRLATEV 697
++K E + E+ E+ K KLQ L + S +++ LEK EV
Sbjct: 467 NTQTKLEHARIKELEQSLLFEKTKADKLQRELEDTRVATVSEKSRIMELEKDLALRVQEV 526
Query: 698 EDLQLEVD 721
+L+ ++
Sbjct: 527 AELRRRLE 534
Score = 38.3 bits (85), Expect = 0.031
Identities = 65/261 (24%), Positives = 110/261 (42%), Gaps = 32/261 (12%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEV---NDLRAGLDHLSNEKAAQEKI----VKQLQHQLN 193
E L+QL + K K E + + E DL + + Q K+ +K+L+ L
Sbjct: 426 ELLNQLEEEKRKVEDLQFRVEEESITKGDLEQKSQISEDPENTQTKLEHARIKELEQSLL 485
Query: 194 EVQSKADEANRTLNDLDAA-----------KKKLSI---ENSDLLRQLE------EAESQ 313
++KAD+ R L D A +K L++ E ++L R+LE + +
Sbjct: 486 FEKTKADKLQRELEDTRVATVSEKSRIMELEKDLALRVQEVAELRRRLESNKPAGDVDMS 545
Query: 314 VSQLSKIKVSLTTQLEDTKRLADEEARERATLLG-KFRNLEHDLDNIREQVEEEAEGKAD 490
+S L +I SL +LE T+ E G + + ++ + E+ ++
Sbjct: 546 LSLLQEIS-SLQEKLEVTRTDHQREITSLKEHFGAREETHQKEIKALYTATEKLSKENES 604
Query: 491 LQRQLSKANAEAQ----LWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVV 658
L+ +L AN E LW+SK E+ + + +EE K L ET E K
Sbjct: 605 LKSKLEHANKENSDVIALWKSKLETAIASHQQAMEELKVSFSKGL--GTETAEFAELK-T 661
Query: 659 ALEKTKQRLATEVEDLQLEVD 721
+EK + E+E+LQ + D
Sbjct: 662 QIEKMRLDYQHEIENLQNQQD 682
>AY847595-1|AAW32538.1| 664|Homo sapiens lamin A/C transcript
variant 1 protein.
Length = 664
Score = 57.6 bits (133), Expect = 5e-08
Identities = 48/200 (24%), Positives = 103/200 (51%), Gaps = 9/200 (4%)
Frame = +2
Query: 152 AQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSK 331
++E + +++ +++ +A +TL+ + + +L +E S + + +E +++ ++
Sbjct: 66 SEEVVSREVSGIKAAYEAELGDARKTLDSVAKERARLQLELSKVREEFKELKARNTKKEG 125
Query: 332 IKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVE--EEAEGKADLQRQ- 502
++ +L+D + L + + +T L + R LE +L ++R QV E A G+A Q Q
Sbjct: 126 DLIAAQARLKDLEALLNSKEAALSTALSEKRTLEGELHDLRGQVAKLEAALGEAKKQLQD 185
Query: 503 --LSKANAEAQLWRSKYESEGVAR--SEELEEAKRKLQARLAEAE--ETIESLNQKVVAL 664
L + AE +L K E + SEEL E KR+ + RL E + + E ++ AL
Sbjct: 186 EMLRRVGAENRLQTMKEELDFQKNIYSEELRETKRRHETRLVEIDNGKQREFESRLADAL 245
Query: 665 EKTKQRLATEVEDLQLEVDR 724
++ + + +VE + E+++
Sbjct: 246 QELRAQHEDQVEQYKKELEK 265
Score = 34.3 bits (75), Expect = 0.50
Identities = 31/144 (21%), Positives = 62/144 (43%), Gaps = 1/144 (0%)
Frame = +2
Query: 128 DHLSNEKAAQEKIVKQLQHQLNEVQS-KADEANRTLNDLDAAKKKLSIENSDLLRQLEEA 304
D L +A E V+Q + +L + S K D A ++ + + + +L +
Sbjct: 243 DALQELRAQHEDQVEQYKKELEKTYSAKLDNARQSA---ERNSNLVGAAHEELQQSRIRI 299
Query: 305 ESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGK 484
+S +QLS+++ L + + L D ARER T E ++ +R +++++ +
Sbjct: 300 DSLSAQLSQLQKQLAAKEAKLRDLEDSLARERDTSRRLLAEKEREMAEMRARMQQQLDEY 359
Query: 485 ADLQRQLSKANAEAQLWRSKYESE 556
+L + E +R E E
Sbjct: 360 QELLDIKLALDMEIHAYRKLLEGE 383
>AB209115-1|BAD92352.1| 1065|Homo sapiens restin isoform a variant
protein.
Length = 1065
Score = 57.6 bits (133), Expect = 5e-08
Identities = 52/230 (22%), Positives = 110/230 (47%), Gaps = 4/230 (1%)
Frame = +2
Query: 41 LDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKA---AQEKIVKQLQHQL-NEVQSK 208
L +L +L+ +AEK +A +E D ++ ++ EK A + KQ +L NE+ +
Sbjct: 694 LQELEELRKQAEKAKAAQTAE--DAMQIMEQMTKEKTETLASLEDTKQTNAKLQNELDTL 751
Query: 209 ADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEE 388
+ + + +L+ +K+ L++EN + +E E+ ++ L+ E+ +LA+E
Sbjct: 752 KENNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQAAAQKSQQLSALQEENVKLAEEL 811
Query: 389 ARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVAR 568
R R + + LE + + Q+ E + ++ + + A Q S + +
Sbjct: 812 GRSRDEVT-SHQKLEEERSVLNNQLLEMKKRESKFIKDADEEKASLQKSISITSALLTEK 870
Query: 569 SEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEV 718
ELE+ + ++ E + +SL+ V LE K +L +V++L+L++
Sbjct: 871 DAELEKLRNEVTVLRGE-NASAKSLHSVVQTLESDKVKLELKVKNLELQL 919
Score = 50.8 bits (116), Expect = 5e-06
Identities = 53/246 (21%), Positives = 116/246 (47%), Gaps = 24/246 (9%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVK--QLQHQLNEVQSK 208
E D LNKL+ +AE + + F+E ++ + +S +++ QE + K Q + Q N + S
Sbjct: 467 EMEDTLNKLQ-EAE-IKKEKFAEASE-----EAVSVQRSMQETVNKLHQKEEQFNMLSSD 519
Query: 209 ADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIK---VSLTTQLEDTKRLA 379
++ L D++A ++ L++ E+ E+ ++++ K+ S T++ D RL
Sbjct: 520 LEKLRENLADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLK 579
Query: 380 DEEARERATLLGKFRN----LEHDLDNIR---EQVEEEAEGK------------ADLQRQ 502
+ + E L K L+ ++++ EQ ++EA K +DL+++
Sbjct: 580 ERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKK 639
Query: 503 LSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQR 682
+ ++ + Q +++YE + EE + LQ L + E+ ++ ++ L + +
Sbjct: 640 METSHNQCQELKARYERATSETKTKHEEILQNLQKTLLDTEDKLKGAREENSGLLQELEE 699
Query: 683 LATEVE 700
L + E
Sbjct: 700 LRKQAE 705
Score = 47.2 bits (107), Expect = 7e-05
Identities = 53/229 (23%), Positives = 107/229 (46%), Gaps = 10/229 (4%)
Frame = +2
Query: 41 LDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEA 220
L +++ L+ K E R + E+ L+ +H + +K +K L + E SK +E+
Sbjct: 289 LQEISSLQEKLEVTRTDHQREITSLK---EHFGAREETHQKEIKAL-YTATEKLSKENES 344
Query: 221 NRTLNDLDAAKKKLSIENSDLLR----QLEEAESQVSQ-LSKIKVS----LTTQLEDTKR 373
++ L+ A K ENSD++ +LE A + Q + ++KVS L T+ +
Sbjct: 345 LKS--KLEHANK----ENSDVIALWKSKLETAIASHQQAMEELKVSFSKGLGTETAEFAE 398
Query: 374 LADEEARERATLLGKFRNLEHDLDNIREQVEEEAEG-KADLQRQLSKANAEAQLWRSKYE 550
L + + R + NL++ D+ R +E E +A L + + + + RSK +
Sbjct: 399 LKTQIEKMRLDYQHEIENLQNQQDSERAAHAKEMEALRAKLMKVIKEKENSLEAIRSKLD 458
Query: 551 SEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEV 697
E+E+ KLQ + E+ E+ +++ V+++++ Q ++
Sbjct: 459 KAEDQHLVEMEDTLNKLQEAEIKKEKFAEA-SEEAVSVQRSMQETVNKL 506
Score = 47.2 bits (107), Expect = 7e-05
Identities = 57/253 (22%), Positives = 117/253 (46%), Gaps = 25/253 (9%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKA-EKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNE 196
+ DM + +Q + AK E+ + + +++DL ++ N+ QE + + + +E
Sbjct: 604 IEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQ--CQE-LKARYERATSE 660
Query: 197 VQSKADEA----NRTLNDLDAAKKKLSIENSDLLRQLEEAESQ----------------V 316
++K +E +TL D + K ENS LL++LEE Q +
Sbjct: 661 TKTKHEEILQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQAEKAKAAQTAEDAMQIM 720
Query: 317 SQLSKIKVSLTTQLEDTKRLADEEARERATLL-GKFRNLEHDLDNIREQVEEEAEGKADL 493
Q++K K LEDTK+ + E TL +N+E +L+ +E + E + +
Sbjct: 721 EQMTKEKTETLASLEDTKQTNAKLQNELDTLKENNLKNVE-ELNKSKELLTVENQKMEEF 779
Query: 494 QRQ---LSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVAL 664
+++ L +A A+ S + E V +EEL ++ ++ + + EE LN +++ +
Sbjct: 780 RKEIETLKQAAAQKSQQLSALQEENVKLAEELGRSRDEVTSH-QKLEEERSVLNNQLLEM 838
Query: 665 EKTKQRLATEVED 703
+K + + + ++
Sbjct: 839 KKRESKFIKDADE 851
Score = 41.9 bits (94), Expect = 0.003
Identities = 64/254 (25%), Positives = 108/254 (42%), Gaps = 25/254 (9%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD 214
E L+QL + K K E Q+ E + G L + + +K+L+ L ++KAD
Sbjct: 177 ELLNQLEEEKRKVEDL--QFRVEEESITKG--DLETQTKLEHARIKELEQSLLFEKTKAD 232
Query: 215 EANRTLNDLDAA-----------KKKLSI---ENSDLLRQLE------EAESQVSQLSKI 334
+ R L D A +K L++ E ++L R+LE + + +S L +I
Sbjct: 233 KLQRELEDTRVATVSEKSRIMELEKDLALRVQEVAELRRRLESNKPAGDVDMSLSLLQEI 292
Query: 335 KVSLTTQLEDTKRLADEEARERATLLG-KFRNLEHDLDNIREQVEEEAEGKADLQRQLSK 511
SL +LE T+ E G + + ++ + E+ ++ L+ +L
Sbjct: 293 S-SLQEKLEVTRTDHQREITSLKEHFGAREETHQKEIKALYTATEKLSKENESLKSKLEH 351
Query: 512 ANAEAQ----LWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQ 679
AN E LW+SK E+ + + +EE K L ET E K +EK +
Sbjct: 352 ANKENSDVIALWKSKLETAIASHQQAMEELKVSFSKGL--GTETAEFAELK-TQIEKMRL 408
Query: 680 RLATEVEDLQLEVD 721
E+E+LQ + D
Sbjct: 409 DYQHEIENLQNQQD 422
Score = 36.3 bits (80), Expect = 0.12
Identities = 39/173 (22%), Positives = 78/173 (45%), Gaps = 8/173 (4%)
Frame = +2
Query: 176 LQHQLNEVQSKADE--ANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLT 349
LQ L E Q ++ A R L + AK + ++ ++L A Q + L
Sbjct: 104 LQEALKEKQQHIEQLLAERDLERAEVAKATSHV--GEIEQELALARDGHDQHV---LELE 158
Query: 350 TQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANA--- 520
+++ + + + RE+ LL + + +++++ +VEEE+ K DL+ Q +A
Sbjct: 159 AKMDQLRTMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLETQTKLEHARIK 218
Query: 521 --EAQLWRSKYESEGVARS-EELEEAKRKLQARLAEAEETIESLNQKVVALEK 670
E L K +++ + R E+ A ++R+ E E+ + Q+V L +
Sbjct: 219 ELEQSLLFEKTKADKLQRELEDTRVATVSEKSRIMELEKDLALRVQEVAELRR 271
>BC114620-1|AAI14621.1| 1756|Homo sapiens periplakin protein.
Length = 1756
Score = 57.2 bits (132), Expect = 6e-08
Identities = 59/242 (24%), Positives = 110/242 (45%), Gaps = 15/242 (6%)
Frame = +2
Query: 44 DQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEAN 223
++L+++K + + + E LRA + + + + +L+ +L +Q + E
Sbjct: 1341 EELSRVKERVVQQEVVRYEEEPGLRAEASAFAESIDVELRQIDKLRAELRRLQRRRTELE 1400
Query: 224 RTLNDLDA---AKKKLSIENSDLLRQL-----EEAESQVSQLSKIKVSLTTQLEDTKRLA 379
R L +L+ A+++ E L ++L EEAE++ KV L + + A
Sbjct: 1401 RQLEELERERQARREAEREVQRLQQRLAALEQEEAEAREKVTHTQKVVLQQDPQQAREHA 1460
Query: 380 ------DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRS 541
+EE R L G+ L L + E+ E + + Q+ K + E ++ R
Sbjct: 1461 LLRLQLEEEQHRRQLLEGELETLRRKLAAL-EKAEVKEKVVLSESVQVEKGDTEQEIQRL 1519
Query: 542 KYESEGVARSE-ELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEV 718
K E +RS+ EL+ +L+ARL+E E ++++ L + +L E E+LQLE
Sbjct: 1520 KSSLEEESRSKRELDVEVSRLEARLSELEFHNSKSSKELDFLREENHKLQLERENLQLET 1579
Query: 719 DR 724
R
Sbjct: 1580 RR 1581
Score = 39.1 bits (87), Expect = 0.018
Identities = 56/256 (21%), Positives = 115/256 (44%), Gaps = 28/256 (10%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEK--AAQEKIVKQLQHQLNEVQSK 208
E QL + A+ + E+ L+ L L E QE +VK++ ++ +++
Sbjct: 948 ESFQQLQRTLAEEQHKNQLLQEELEALQLQLRALEQETRDGGQEYVVKEVL-RIEPDRAQ 1006
Query: 209 ADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEE 388
ADE + +L+A +++ +++L + + + S+ + +T + + +L ++
Sbjct: 1007 ADEVLQLREELEALRRQKGAREAEVLLLQQRVAALAEEKSRAQEKVTEK--EVVKLQNDP 1064
Query: 389 ARERATLLGKFRNLEHD---LDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYE--- 550
E +++ L+ D D +RE+ EEE D ++L K A A+ + E
Sbjct: 1065 QLE-----AEYQQLQEDHQRQDQLREKQEEELSFLQDKLKRLEKERAMAEGKITVKEVLK 1119
Query: 551 -SEGVARSEELEEAKRKLQ-----ARLAEAEET--------IESLNQKVVALEKTKQ--- 679
+ A E+ + R+ + AR ++ E+T +E N KVV EK ++
Sbjct: 1120 VEKDAATEREVSDLTRQYEDEAAKARASQREKTELLRKIWALEEENAKVVVQEKVREIVR 1179
Query: 680 ---RLATEVEDLQLEV 718
+ +EV +L+LE+
Sbjct: 1180 PDPKAESEVANLRLEL 1195
Score = 38.7 bits (86), Expect = 0.023
Identities = 43/194 (22%), Positives = 87/194 (44%)
Frame = +2
Query: 134 LSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQ 313
L N+K ++I + Q ++ ++ + + + + + D + +KL LL S
Sbjct: 767 LKNQKNLLDEIASREQ-EVQKICANSQQYQQAVKDYELEAEKLR----SLLDLENGRSSH 821
Query: 314 VSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADL 493
VS+ ++++ T E+ LA + A + +NLE L+ +R+Q E E + L
Sbjct: 822 VSKRARLQSPATKVKEEEAALAAKFTEVYAINRQRLQNLEFALNLLRQQPEVEVTHET-L 880
Query: 494 QRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKT 673
QR + E + W+ + E +E E +R+L+ + +E I +L +
Sbjct: 881 QRNRPDSGVE-EAWKIRKE------LDEETERRRQLENEVKSTQEEIWTLRNQGPQESVV 933
Query: 674 KQRLATEVEDLQLE 715
++ + +V D LE
Sbjct: 934 RKEVLKKVPDPVLE 947
Score = 38.7 bits (86), Expect = 0.023
Identities = 26/93 (27%), Positives = 46/93 (49%), Gaps = 8/93 (8%)
Frame = +2
Query: 449 IREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEEL--------EEAKRKLQ 604
IR++++EE E + L+ ++ E R++ E V R E L EE+ ++LQ
Sbjct: 895 IRKELDEETERRRQLENEVKSTQEEIWTLRNQGPQESVVRKEVLKKVPDPVLEESFQQLQ 954
Query: 605 ARLAEAEETIESLNQKVVALEKTKQRLATEVED 703
LAE + + L +++ AL+ + L E D
Sbjct: 955 RTLAEEQHKNQLLQEELEALQLQLRALEQETRD 987
Score = 33.1 bits (72), Expect = 1.2
Identities = 51/210 (24%), Positives = 92/210 (43%), Gaps = 6/210 (2%)
Frame = +2
Query: 113 LRAGLDHLSNEKAAQEK-IVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLR 289
L AGLD ++++ QEK I L+ L + ++ D A R + + + L IE + R
Sbjct: 507 LLAGLDKVASDLDRQEKAITGILRPPLEQGRAVQDSAERAKDLKNITNELLRIE-PEKTR 565
Query: 290 QLEEAESQVSQL--SKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQV 463
E E+ + L S L TQ+EDT R + LL + + + + +
Sbjct: 566 STAEGEAFIQALPGSGTTPLLRTQVEDTNR----KYEHLLQLLDLAQEKVDVANRLEKSL 621
Query: 464 EEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQAR---LAEAEETI 634
++ E A + L++ + + R +S+G +EL +LQA+ L E E+ +
Sbjct: 622 QQSWELLATHENHLNQDDTVPESSR-VLDSKG----QELAAMACELQAQKSLLGEVEQNL 676
Query: 635 ESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
++ Q L Q ++E + EV +
Sbjct: 677 QAAKQCSSTLASRFQEHCPDLERQEAEVHK 706
>AB011140-1|BAA25494.1| 1426|Homo sapiens KIAA0568 protein protein.
Length = 1426
Score = 57.2 bits (132), Expect = 6e-08
Identities = 59/242 (24%), Positives = 110/242 (45%), Gaps = 15/242 (6%)
Frame = +2
Query: 44 DQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEAN 223
++L+++K + + + E LRA + + + + +L+ +L +Q + E
Sbjct: 1011 EELSRVKERVVQQEVVRYEEEPGLRAEASAFAESIDVELRQIDKLRAELRRLQRRRTELE 1070
Query: 224 RTLNDLDA---AKKKLSIENSDLLRQL-----EEAESQVSQLSKIKVSLTTQLEDTKRLA 379
R L +L+ A+++ E L ++L EEAE++ KV L + + A
Sbjct: 1071 RQLEELERERQARREAEREVQRLQQRLAALEQEEAEAREKVTHTQKVVLQQDPQQAREHA 1130
Query: 380 ------DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRS 541
+EE R L G+ L L + E+ E + + Q+ K + E ++ R
Sbjct: 1131 LLRLQLEEEQHRRQLLEGELETLRRKLAAL-EKAEVKEKVVLSESVQVEKGDTEQEIQRL 1189
Query: 542 KYESEGVARSE-ELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEV 718
K E +RS+ EL+ +L+ARL+E E ++++ L + +L E E+LQLE
Sbjct: 1190 KSSLEEESRSKRELDVEVSRLEARLSELEFHNSKSSKELDFLREENHKLQLERENLQLET 1249
Query: 719 DR 724
R
Sbjct: 1250 RR 1251
Score = 39.1 bits (87), Expect = 0.018
Identities = 56/256 (21%), Positives = 115/256 (44%), Gaps = 28/256 (10%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEK--AAQEKIVKQLQHQLNEVQSK 208
E QL + A+ + E+ L+ L L E QE +VK++ ++ +++
Sbjct: 618 ESFQQLQRTLAEEQHKNQLLQEELEALQLQLRALEQETRDGGQEYVVKEVL-RIEPDRAQ 676
Query: 209 ADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEE 388
ADE + +L+A +++ +++L + + + S+ + +T + + +L ++
Sbjct: 677 ADEVLQLREELEALRRQKGAREAEVLLLQQRVAALAEEKSRAQEKVTEK--EVVKLQNDP 734
Query: 389 ARERATLLGKFRNLEHD---LDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYE--- 550
E +++ L+ D D +RE+ EEE D ++L K A A+ + E
Sbjct: 735 QLE-----AEYQQLQEDHQRQDQLREKQEEELSFLQDKLKRLEKERAMAEGKITVKEVLK 789
Query: 551 -SEGVARSEELEEAKRKLQ-----ARLAEAEET--------IESLNQKVVALEKTKQ--- 679
+ A E+ + R+ + AR ++ E+T +E N KVV EK ++
Sbjct: 790 VEKDAATEREVSDLTRQYEDEAAKARASQREKTELLRKIWALEEENAKVVVQEKVREIVR 849
Query: 680 ---RLATEVEDLQLEV 718
+ +EV +L+LE+
Sbjct: 850 PDPKAESEVANLRLEL 865
Score = 38.7 bits (86), Expect = 0.023
Identities = 43/194 (22%), Positives = 87/194 (44%)
Frame = +2
Query: 134 LSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQ 313
L N+K ++I + Q ++ ++ + + + + + D + +KL LL S
Sbjct: 437 LKNQKNLLDEIASREQ-EVQKICANSQQYQQAVKDYELEAEKLR----SLLDLENGRSSH 491
Query: 314 VSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADL 493
VS+ ++++ T E+ LA + A + +NLE L+ +R+Q E E + L
Sbjct: 492 VSKRARLQSPATKVKEEEAALAAKFTEVYAINRQRLQNLEFALNLLRQQPEVEVTHET-L 550
Query: 494 QRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKT 673
QR + E + W+ + E +E E +R+L+ + +E I +L +
Sbjct: 551 QRNRPDSGVE-EAWKIRKE------LDEETERRRQLENEVKSTQEEIWTLRNQGPQESVV 603
Query: 674 KQRLATEVEDLQLE 715
++ + +V D LE
Sbjct: 604 RKEVLKKVPDPVLE 617
Score = 38.7 bits (86), Expect = 0.023
Identities = 26/93 (27%), Positives = 46/93 (49%), Gaps = 8/93 (8%)
Frame = +2
Query: 449 IREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEEL--------EEAKRKLQ 604
IR++++EE E + L+ ++ E R++ E V R E L EE+ ++LQ
Sbjct: 565 IRKELDEETERRRQLENEVKSTQEEIWTLRNQGPQESVVRKEVLKKVPDPVLEESFQQLQ 624
Query: 605 ARLAEAEETIESLNQKVVALEKTKQRLATEVED 703
LAE + + L +++ AL+ + L E D
Sbjct: 625 RTLAEEQHKNQLLQEELEALQLQLRALEQETRD 657
Score = 33.1 bits (72), Expect = 1.2
Identities = 51/210 (24%), Positives = 92/210 (43%), Gaps = 6/210 (2%)
Frame = +2
Query: 113 LRAGLDHLSNEKAAQEK-IVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLR 289
L AGLD ++++ QEK I L+ L + ++ D A R + + + L IE + R
Sbjct: 177 LLAGLDKVASDLDRQEKAITGILRPPLEQGRAVQDSAERAKDLKNITNELLRIE-PEKTR 235
Query: 290 QLEEAESQVSQL--SKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQV 463
E E+ + L S L TQ+EDT R + LL + + + + +
Sbjct: 236 STAEGEAFIQALPGSGTTPLLRTQVEDTNR----KYEHLLQLLDLAQEKVDVANRLEKSL 291
Query: 464 EEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQAR---LAEAEETI 634
++ E A + L++ + + R +S+G +EL +LQA+ L E E+ +
Sbjct: 292 QQSWELLATHENHLNQDDTVPESSR-VLDSKG----QELAAMACELQAQKSLLGEVEQNL 346
Query: 635 ESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
++ Q L Q ++E + EV +
Sbjct: 347 QAAKQCSSTLASRFQEHCPDLERQEAEVHK 376
>BX530088-3|CAI95784.1| 810|Homo sapiens GRIP1 associated protein 1
protein.
Length = 810
Score = 56.8 bits (131), Expect = 8e-08
Identities = 53/235 (22%), Positives = 109/235 (46%), Gaps = 6/235 (2%)
Frame = +2
Query: 32 GEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKA 211
GE+L+ L+A ++ + E+N LR L+ E Q+ + L Q +++ S+
Sbjct: 301 GERLEHAAALRALQDQIQTAKTQELNMLREQTTGLAAELQQQQAEYEDLMGQKDDLNSQL 360
Query: 212 DEANRTLNDLDAAKKKLSIENSDLLRQLEE----AESQVSQLSKIKV-SLTTQLEDTKRL 376
E+ R + L +++ E L ++L+E AE + + L ++ + +L + + + L
Sbjct: 361 QESLRANSRLLEQLQEIGQEKEQLTQELQEARKSAEKRKAMLDELAMETLQEKSQHKEEL 420
Query: 377 ADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESE 556
R +LG E +L + E + + E R+ E + + E E
Sbjct: 421 GAVRLRHEKEVLGVRARYERELRELHEDKKRQEEELRGQIREEKARTRELETLQQTVE-E 479
Query: 557 GVARSEELEEAKRKLQARLAEAEETIESLNQ-KVVALEKTKQRLATEVEDLQLEV 718
A+ ++ AK + RL EAEE+++ Q + AL++ +++ A E++ + E+
Sbjct: 480 LQAQVHSMDGAKGWFERRLKEAEESLQQQQQEQEEALKQCREQHAAELKGKEEEL 534
>X95654-1|CAA64956.1| 976|Homo sapiens polypeptide of 976 aa protein.
Length = 976
Score = 56.4 bits (130), Expect = 1e-07
Identities = 50/207 (24%), Positives = 95/207 (45%), Gaps = 3/207 (1%)
Frame = +2
Query: 101 EVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSD 280
EV+DL L ++ + K VK L+ +L + K E N L K+L+ E SD
Sbjct: 477 EVHDLEIQLTAITTSEQYYSKEVKDLKTELENEKLKNTELTSHCNKLSLENKELTQETSD 536
Query: 281 LLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQ 460
+ +L+ + ++ K + + Q+E+ L + E + R L L+ D ++ +
Sbjct: 537 MTLELKNQQEDINNNKKQEERMLKQIEN---LQETETQLRNELEYVREELKQKRDEVKCK 593
Query: 461 VEEEAEGKADLQRQLSKAN---AEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEET 631
+++ E +L++Q+ N E Q + +G A S++L + K+ + E
Sbjct: 594 LDKSEENCNNLRKQVENKNKYIEELQQENKALKKKGTAESKQLNVYEIKVN----KLELE 649
Query: 632 IESLNQKVVALEKTKQRLATEVEDLQL 712
+ES QK + T Q+ E+ED ++
Sbjct: 650 LESAKQKFGEITDTYQK---EIEDKKI 673
Score = 40.3 bits (90), Expect = 0.008
Identities = 39/232 (16%), Positives = 100/232 (43%), Gaps = 3/232 (1%)
Frame = +2
Query: 38 QLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADE 217
+L+++ KL E E+ + + L E EKI ++L+ E+
Sbjct: 418 ELEEMTKLTNNKEVE----LEELKKVLGEKETLLYENKQFEKIAEELKGTEQELIGLLQA 473
Query: 218 ANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARE 397
+ ++DL+ ++ +++++ ++++ LT+ E +E
Sbjct: 474 REKEVHDLEIQLTAITTSEQYYSKEVKDLKTELENEKLKNTELTSHCNKLSLENKELTQE 533
Query: 398 RATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYE---SEGVAR 568
+ + + +N + D++N ++Q E + +LQ ++ E + R + + E +
Sbjct: 534 TSDMTLELKNQQEDINNNKKQEERMLKQIENLQETETQLRNELEYVREELKQKRDEVKCK 593
Query: 569 SEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
++ EE L+ ++ + IE L Q+ AL+K + ++ +++V++
Sbjct: 594 LDKSEENCNNLRKQVENKNKYIEELQQENKALKKKGTAESKQLNVYEIKVNK 645
Score = 36.3 bits (80), Expect = 0.12
Identities = 54/212 (25%), Positives = 91/212 (42%), Gaps = 22/212 (10%)
Frame = +2
Query: 146 KAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQL 325
K EKI Q E+ K + + L + + K+ DL LEE+ +V+QL
Sbjct: 244 KEDYEKIQHLEQEYKKEINDKEKQVSLLLIQITEKENKMK----DLTFLLEESRDKVNQL 299
Query: 326 SK--------IKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEG 481
+ +K S+ Q TK L D + + ++ + + LE DL + + + E
Sbjct: 300 EEKTKLQSENLKQSIEKQHHLTKELEDIKVSLQRSVSTQ-KALEEDLQIATKTICQLTEE 358
Query: 482 KADLQRQLSKANAEAQLWRSKYES-----EGVARSE---------ELEEAKRKLQARLAE 619
K + +KA A +++E+ E + R+E +L+ +LQ + +E
Sbjct: 359 KETQMEESNKARAAHSFVVTEFETTVCSLEELLRTEQQRLEKNEDQLKILTMELQKKSSE 418
Query: 620 AEETIESLNQKVVALEKTKQRLATEVEDLQLE 715
EE + N K V LE+ K+ L E E L E
Sbjct: 419 LEEMTKLTNNKEVELEELKKVLG-EKETLLYE 449
Score = 34.7 bits (76), Expect = 0.38
Identities = 34/204 (16%), Positives = 91/204 (44%), Gaps = 3/204 (1%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSK-A 211
E NKL + ++ + +L+ + ++N K +E+++KQ+++ L E +++
Sbjct: 515 ELTSHCNKLSLENKELTQETSDMTLELKNQQEDINNNKKQEERMLKQIEN-LQETETQLR 573
Query: 212 DEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEA 391
+E +L + ++ + QV +K L + + K+ E+
Sbjct: 574 NELEYVREELKQKRDEVKCKLDKSEENCNNLRKQVENKNKYIEELQQENKALKKKGTAES 633
Query: 392 RERATLLGKFRNLEHDLDNIREQVEE--EAEGKADLQRQLSKANAEAQLWRSKYESEGVA 565
++ K LE +L++ +++ E + K +++S+ N ++ ++K ++
Sbjct: 634 KQLNVYEIKVNKLELELESAKQKFGEITDTYQKEIEDKKISEENLLEEVEKAKVIADEAV 693
Query: 566 RSEELEEAKRKLQARLAEAEETIE 637
+ + +E ++ Q ++AE +E
Sbjct: 694 KLQ--KEIDKRCQHKIAEMVALME 715
>X64838-1|CAA46050.1| 1427|Homo sapiens restin protein.
Length = 1427
Score = 56.4 bits (130), Expect = 1e-07
Identities = 51/230 (22%), Positives = 110/230 (47%), Gaps = 4/230 (1%)
Frame = +2
Query: 41 LDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKA---AQEKIVKQLQHQL-NEVQSK 208
L +L +L+ +A+K +A +E D ++ ++ EK A + KQ +L NE+ +
Sbjct: 1058 LQELEELRKQADKAKAAQTAE--DAMQIMEQMTKEKTETLASLEDTKQTNAKLQNELDTL 1115
Query: 209 ADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEE 388
+ + + +L+ +K+ L++EN + +E E+ ++ L+ E+ +LA+E
Sbjct: 1116 KENNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQAAAQKSQQLSALQEENVKLAEEL 1175
Query: 389 ARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVAR 568
R R + + LE + + Q+ E + ++ + + A Q S + +
Sbjct: 1176 GRSRDEVT-SHQKLEEERSVLNNQLLEMKKRESKFIKDADEEKASLQKSISITSALLTEK 1234
Query: 569 SEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEV 718
ELE+ + ++ E + +SL+ V LE K +L +V++L+L++
Sbjct: 1235 DAELEKLRNEVTVLRGE-NASAKSLHSVVQTLESDKVKLELKVKNLELQL 1283
Score = 50.8 bits (116), Expect = 5e-06
Identities = 53/259 (20%), Positives = 120/259 (46%), Gaps = 24/259 (9%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVK--QLQHQLN 193
++++ E L +++++K EK Q E A + +S +++ QE + K Q + Q N
Sbjct: 821 LTNLQENLSEVSQVKETLEK-ELQILKE-KFAEASEEAVSVQRSMQETVNKLHQKEEQFN 878
Query: 194 EVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIK---VSLTTQLED 364
+ S ++ L D++A ++ L++ E+ E+ ++++ K+ S T++ D
Sbjct: 879 MLSSDLEKLRENLADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMND 938
Query: 365 TKRLADEEARERATLLGKFRN----LEHDLDNIR---EQVEEEAEGK------------A 487
RL + + E L K L+ ++++ EQ ++EA K +
Sbjct: 939 ELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLS 998
Query: 488 DLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALE 667
DL++++ ++ + Q +++YE + EE + LQ L + E+ ++ ++
Sbjct: 999 DLEKKMETSHNQCQELKARYERATSETKTKHEEILQNLQKTLLDTEDKLKGAREE----- 1053
Query: 668 KTKQRLATEVEDLQLEVDR 724
L E+E+L+ + D+
Sbjct: 1054 --NSGLLQELEELRKQADK 1070
Score = 45.6 bits (103), Expect = 2e-04
Identities = 41/204 (20%), Positives = 84/204 (41%), Gaps = 1/204 (0%)
Frame = +2
Query: 116 RAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQL 295
++ + L + A EK +K L+ + N SKA R L + L S++ +
Sbjct: 776 KSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVK 835
Query: 296 EEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEE-E 472
E E ++ L + + + +R E + +F L DL+ +RE + + E
Sbjct: 836 ETLEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADME 895
Query: 473 AEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQK 652
A+ + +R+ A+ +L E ++ + K + RL E + +E L K
Sbjct: 896 AKFREKDEREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERD--VEELQLK 953
Query: 653 VVALEKTKQRLATEVEDLQLEVDR 724
+ + L +ED+ ++ ++
Sbjct: 954 LTKANENASFLQKSIEDMTVKAEQ 977
Score = 41.9 bits (94), Expect = 0.003
Identities = 64/254 (25%), Positives = 108/254 (42%), Gaps = 25/254 (9%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD 214
E L+QL + K K E Q+ E + G L + + +K+L+ L ++KAD
Sbjct: 426 ELLNQLEEEKRKVEDL--QFRVEEESITKG--DLETQTKLEHARIKELEQSLLFEKTKAD 481
Query: 215 EANRTLNDLDAA-----------KKKLSI---ENSDLLRQLE------EAESQVSQLSKI 334
+ R L D A +K L++ E ++L R+LE + + +S L +I
Sbjct: 482 KLQRELEDTRVATVSEKSRIMELEKDLALRVQEVAELRRRLESNKPAGDVDMSLSLLQEI 541
Query: 335 KVSLTTQLEDTKRLADEEARERATLLG-KFRNLEHDLDNIREQVEEEAEGKADLQRQLSK 511
SL +LE T+ E G + + ++ + E+ ++ L+ +L
Sbjct: 542 S-SLQEKLEVTRTDHQREITSLKEHFGAREETHQKEIKALYTATEKLSKENESLKSKLEH 600
Query: 512 ANAEAQ----LWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQ 679
AN E LW+SK E+ + + +EE K L ET E K +EK +
Sbjct: 601 ANKENSDVIALWKSKLETAIASHQQAMEELKVSFSKGL--GTETAEFAELK-TQIEKMRL 657
Query: 680 RLATEVEDLQLEVD 721
E+E+LQ + D
Sbjct: 658 DYQHEIENLQNQQD 671
Score = 36.3 bits (80), Expect = 0.12
Identities = 39/173 (22%), Positives = 78/173 (45%), Gaps = 8/173 (4%)
Frame = +2
Query: 176 LQHQLNEVQSKADE--ANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLT 349
LQ L E Q ++ A R L + AK + ++ ++L A Q + L
Sbjct: 353 LQEALKEKQQHIEQLLAERDLERAEVAKATSHV--GEIEQELALARDGHDQHV---LELE 407
Query: 350 TQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANA--- 520
+++ + + + RE+ LL + + +++++ +VEEE+ K DL+ Q +A
Sbjct: 408 AKMDQLRTMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLETQTKLEHARIK 467
Query: 521 --EAQLWRSKYESEGVARS-EELEEAKRKLQARLAEAEETIESLNQKVVALEK 670
E L K +++ + R E+ A ++R+ E E+ + Q+V L +
Sbjct: 468 ELEQSLLFEKTKADKLQRELEDTRVATVSEKSRIMELEKDLALRVQEVAELRR 520
>BC126305-1|AAI26306.1| 1438|Homo sapiens CLIP1 protein protein.
Length = 1438
Score = 56.4 bits (130), Expect = 1e-07
Identities = 51/230 (22%), Positives = 110/230 (47%), Gaps = 4/230 (1%)
Frame = +2
Query: 41 LDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKA---AQEKIVKQLQHQL-NEVQSK 208
L +L +L+ +A+K +A +E D ++ ++ EK A + KQ +L NE+ +
Sbjct: 1069 LQELEELRKQADKAKAAQTAE--DAMQIMEQMTKEKTETLASLEDTKQTNAKLQNELDTL 1126
Query: 209 ADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEE 388
+ + + +L+ +K+ L++EN + +E E+ ++ L+ E+ +LA+E
Sbjct: 1127 KENNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQAAAQKSQQLSALQEENVKLAEEL 1186
Query: 389 ARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVAR 568
R R + + LE + + Q+ E + ++ + + A Q S + +
Sbjct: 1187 GRSRDEVT-SHQKLEEERSVLNNQLLEMKKRESKFIKDADEEKASLQKSISITSALLTEK 1245
Query: 569 SEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEV 718
ELE+ + ++ E + +SL+ V LE K +L +V++L+L++
Sbjct: 1246 DAELEKLRNEVTVLRGE-NASAKSLHSVVQTLESDKVKLELKVKNLELQL 1294
Score = 50.8 bits (116), Expect = 5e-06
Identities = 53/259 (20%), Positives = 120/259 (46%), Gaps = 24/259 (9%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVK--QLQHQLN 193
++++ E L +++++K EK Q E A + +S +++ QE + K Q + Q N
Sbjct: 832 LTNLQENLSEVSQVKETLEK-ELQILKE-KFAEASEEAVSVQRSMQETVNKLHQKEEQFN 889
Query: 194 EVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIK---VSLTTQLED 364
+ S ++ L D++A ++ L++ E+ E+ ++++ K+ S T++ D
Sbjct: 890 MLSSDLEKLRENLADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMND 949
Query: 365 TKRLADEEARERATLLGKFRN----LEHDLDNIR---EQVEEEAEGK------------A 487
RL + + E L K L+ ++++ EQ ++EA K +
Sbjct: 950 ELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLS 1009
Query: 488 DLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALE 667
DL++++ ++ + Q +++YE + EE + LQ L + E+ ++ ++
Sbjct: 1010 DLEKKMETSHNQCQELKARYERATSETKTKHEEILQNLQKTLLDTEDKLKGAREE----- 1064
Query: 668 KTKQRLATEVEDLQLEVDR 724
L E+E+L+ + D+
Sbjct: 1065 --NSGLLQELEELRKQADK 1081
Score = 45.6 bits (103), Expect = 2e-04
Identities = 41/204 (20%), Positives = 84/204 (41%), Gaps = 1/204 (0%)
Frame = +2
Query: 116 RAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQL 295
++ + L + A EK +K L+ + N SKA R L + L S++ +
Sbjct: 787 KSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVK 846
Query: 296 EEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEE-E 472
E E ++ L + + + +R E + +F L DL+ +RE + + E
Sbjct: 847 ETLEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADME 906
Query: 473 AEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQK 652
A+ + +R+ A+ +L E ++ + K + RL E + +E L K
Sbjct: 907 AKFREKDEREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERD--VEELQLK 964
Query: 653 VVALEKTKQRLATEVEDLQLEVDR 724
+ + L +ED+ ++ ++
Sbjct: 965 LTKANENASFLQKSIEDMTVKAEQ 988
Score = 43.2 bits (97), Expect = 0.001
Identities = 43/188 (22%), Positives = 86/188 (45%), Gaps = 6/188 (3%)
Frame = +2
Query: 176 LQHQLNEVQSKADE--ANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLT 349
LQ L E Q ++ A R L + AK + ++ ++L A Q + L
Sbjct: 353 LQEALKEKQQHIEQLLAERDLERAEVAKATSHV--GEIEQELALARDGHDQHV---LELE 407
Query: 350 TQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQ 529
+++ + + + RE+ LL + + +++++ +VEEE+ K DL+ Q S+ + + +
Sbjct: 408 AKMDQLRTMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLE-QKSQISEDPE 466
Query: 530 LWRSKYESEGVARSEE---LEEAKR-KLQARLAEAEETIESLNQKVVALEKTKQRLATEV 697
++K E + E+ E+ K KLQ L + S +++ LEK EV
Sbjct: 467 NTQTKLEHARIKELEQSLLFEKTKADKLQRELEDTRVATVSEKSRIMELEKDLALRVQEV 526
Query: 698 EDLQLEVD 721
+L+ ++
Sbjct: 527 AELRRRLE 534
Score = 38.3 bits (85), Expect = 0.031
Identities = 65/261 (24%), Positives = 110/261 (42%), Gaps = 32/261 (12%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEV---NDLRAGLDHLSNEKAAQEKI----VKQLQHQLN 193
E L+QL + K K E + + E DL + + Q K+ +K+L+ L
Sbjct: 426 ELLNQLEEEKRKVEDLQFRVEEESITKGDLEQKSQISEDPENTQTKLEHARIKELEQSLL 485
Query: 194 EVQSKADEANRTLNDLDAA-----------KKKLSI---ENSDLLRQLE------EAESQ 313
++KAD+ R L D A +K L++ E ++L R+LE + +
Sbjct: 486 FEKTKADKLQRELEDTRVATVSEKSRIMELEKDLALRVQEVAELRRRLESNKPAGDVDMS 545
Query: 314 VSQLSKIKVSLTTQLEDTKRLADEEARERATLLG-KFRNLEHDLDNIREQVEEEAEGKAD 490
+S L +I SL +LE T+ E G + + ++ + E+ ++
Sbjct: 546 LSLLQEIS-SLQEKLEVTRTDHQREITSLKEHFGAREETHQKEIKALYTATEKLSKENES 604
Query: 491 LQRQLSKANAEAQ----LWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVV 658
L+ +L AN E LW+SK E+ + + +EE K L ET E K
Sbjct: 605 LKSKLEHANKENSDVIALWKSKLETAIASHQQAMEELKVSFSKGL--GTETAEFAELK-T 661
Query: 659 ALEKTKQRLATEVEDLQLEVD 721
+EK + E+E+LQ + D
Sbjct: 662 QIEKMRLDYQHEIENLQNQQD 682
>BC126266-1|AAI26267.1| 976|Homo sapiens synaptonemal complex protein
1 protein.
Length = 976
Score = 56.4 bits (130), Expect = 1e-07
Identities = 50/207 (24%), Positives = 95/207 (45%), Gaps = 3/207 (1%)
Frame = +2
Query: 101 EVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSD 280
EV+DL L ++ + K VK L+ +L + K E N L K+L+ E SD
Sbjct: 477 EVHDLEIQLTAITTSEQYYSKEVKDLKTELENEKLKNTELTSHCNKLSLENKELTQETSD 536
Query: 281 LLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQ 460
+ +L+ + ++ K + + Q+E+ L + E + R L L+ D ++ +
Sbjct: 537 MTLELKNQQEDINNNKKQEERMLKQIEN---LQETETQLRNELEYVREELKQKRDEVKCK 593
Query: 461 VEEEAEGKADLQRQLSKAN---AEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEET 631
+++ E +L++Q+ N E Q + +G A S++L + K+ + E
Sbjct: 594 LDKSEENCNNLRKQVENKNKYIEELQQENKALKKKGTAESKQLNVYEIKVN----KLELE 649
Query: 632 IESLNQKVVALEKTKQRLATEVEDLQL 712
+ES QK + T Q+ E+ED ++
Sbjct: 650 LESAKQKFGEITDTYQK---EIEDKKI 673
Score = 40.3 bits (90), Expect = 0.008
Identities = 39/232 (16%), Positives = 100/232 (43%), Gaps = 3/232 (1%)
Frame = +2
Query: 38 QLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADE 217
+L+++ KL E E+ + + L E EKI ++L+ E+
Sbjct: 418 ELEEMTKLTNNKEVE----LEELKKVLGEKETLLYENKQFEKIAEELKGTEQELIGLLQA 473
Query: 218 ANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARE 397
+ ++DL+ ++ +++++ ++++ LT+ E +E
Sbjct: 474 REKEVHDLEIQLTAITTSEQYYSKEVKDLKTELENEKLKNTELTSHCNKLSLENKELTQE 533
Query: 398 RATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYE---SEGVAR 568
+ + + +N + D++N ++Q E + +LQ ++ E + R + + E +
Sbjct: 534 TSDMTLELKNQQEDINNNKKQEERMLKQIENLQETETQLRNELEYVREELKQKRDEVKCK 593
Query: 569 SEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
++ EE L+ ++ + IE L Q+ AL+K + ++ +++V++
Sbjct: 594 LDKSEENCNNLRKQVENKNKYIEELQQENKALKKKGTAESKQLNVYEIKVNK 645
Score = 36.3 bits (80), Expect = 0.12
Identities = 54/212 (25%), Positives = 91/212 (42%), Gaps = 22/212 (10%)
Frame = +2
Query: 146 KAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQL 325
K EKI Q E+ K + + L + + K+ DL LEE+ +V+QL
Sbjct: 244 KEDYEKIQHLEQEYKKEINDKEKQVSLLLIQITEKENKMK----DLTFLLEESRDKVNQL 299
Query: 326 SK--------IKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEG 481
+ +K S+ Q TK L D + + ++ + + LE DL + + + E
Sbjct: 300 EEKTKLQSENLKQSIEKQHHLTKELEDIKVSLQRSVSTQ-KALEEDLQIATKTICQLTEE 358
Query: 482 KADLQRQLSKANAEAQLWRSKYES-----EGVARSE---------ELEEAKRKLQARLAE 619
K + +KA A +++E+ E + R+E +L+ +LQ + +E
Sbjct: 359 KETQMEESNKARAAHSFVVTEFETTVCSLEELLRTEQQRLEKNEDQLKILTMELQKKSSE 418
Query: 620 AEETIESLNQKVVALEKTKQRLATEVEDLQLE 715
EE + N K V LE+ K+ L E E L E
Sbjct: 419 LEEMTKLTNNKEVELEELKKVLG-EKETLLYE 449
Score = 34.7 bits (76), Expect = 0.38
Identities = 34/204 (16%), Positives = 91/204 (44%), Gaps = 3/204 (1%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSK-A 211
E NKL + ++ + +L+ + ++N K +E+++KQ+++ L E +++
Sbjct: 515 ELTSHCNKLSLENKELTQETSDMTLELKNQQEDINNNKKQEERMLKQIEN-LQETETQLR 573
Query: 212 DEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEA 391
+E +L + ++ + QV +K L + + K+ E+
Sbjct: 574 NELEYVREELKQKRDEVKCKLDKSEENCNNLRKQVENKNKYIEELQQENKALKKKGTAES 633
Query: 392 RERATLLGKFRNLEHDLDNIREQVEE--EAEGKADLQRQLSKANAEAQLWRSKYESEGVA 565
++ K LE +L++ +++ E + K +++S+ N ++ ++K ++
Sbjct: 634 KQLNVYEIKVNKLELELESAKQKFGEITDTYQKEIEDKKISEENLLEEVEKAKVIADEAV 693
Query: 566 RSEELEEAKRKLQARLAEAEETIE 637
+ + +E ++ Q ++AE +E
Sbjct: 694 KLQ--KEIDKRCQHKIAEMVALME 715
>BC114213-1|AAI14214.1| 1392|Homo sapiens CAP-GLY domain containing
linker protein 1 protein.
Length = 1392
Score = 56.4 bits (130), Expect = 1e-07
Identities = 51/230 (22%), Positives = 110/230 (47%), Gaps = 4/230 (1%)
Frame = +2
Query: 41 LDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKA---AQEKIVKQLQHQL-NEVQSK 208
L +L +L+ +A+K +A +E D ++ ++ EK A + KQ +L NE+ +
Sbjct: 1023 LQELEELRKQADKAKAAQTAE--DAMQIMEQMTKEKTETLASLEDTKQTNAKLQNELDTL 1080
Query: 209 ADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEE 388
+ + + +L+ +K+ L++EN + +E E+ ++ L+ E+ +LA+E
Sbjct: 1081 KENNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQAAAQKSQQLSALQEENVKLAEEL 1140
Query: 389 ARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVAR 568
R R + + LE + + Q+ E + ++ + + A Q S + +
Sbjct: 1141 GRSRDEVT-SHQKLEEERSVLNNQLLEMKKRESKFIKDADEEKASLQKSISITSALLTEK 1199
Query: 569 SEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEV 718
ELE+ + ++ E + +SL+ V LE K +L +V++L+L++
Sbjct: 1200 DAELEKLRNEVTVLRGE-NASAKSLHSVVQTLESDKVKLELKVKNLELQL 1248
Score = 50.8 bits (116), Expect = 5e-06
Identities = 53/259 (20%), Positives = 120/259 (46%), Gaps = 24/259 (9%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVK--QLQHQLN 193
++++ E L +++++K EK Q E A + +S +++ QE + K Q + Q N
Sbjct: 786 LTNLQENLSEVSQVKETLEK-ELQILKE-KFAEASEEAVSVQRSMQETVNKLHQKEEQFN 843
Query: 194 EVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIK---VSLTTQLED 364
+ S ++ L D++A ++ L++ E+ E+ ++++ K+ S T++ D
Sbjct: 844 MLSSDLEKLRENLADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMND 903
Query: 365 TKRLADEEARERATLLGKFRN----LEHDLDNIR---EQVEEEAEGK------------A 487
RL + + E L K L+ ++++ EQ ++EA K +
Sbjct: 904 ELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLS 963
Query: 488 DLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALE 667
DL++++ ++ + Q +++YE + EE + LQ L + E+ ++ ++
Sbjct: 964 DLEKKMETSHNQCQELKARYERATSETKTKHEEILQNLQKTLLDTEDKLKGAREE----- 1018
Query: 668 KTKQRLATEVEDLQLEVDR 724
L E+E+L+ + D+
Sbjct: 1019 --NSGLLQELEELRKQADK 1035
Score = 45.6 bits (103), Expect = 2e-04
Identities = 41/204 (20%), Positives = 84/204 (41%), Gaps = 1/204 (0%)
Frame = +2
Query: 116 RAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQL 295
++ + L + A EK +K L+ + N SKA R L + L S++ +
Sbjct: 741 KSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVK 800
Query: 296 EEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEE-E 472
E E ++ L + + + +R E + +F L DL+ +RE + + E
Sbjct: 801 ETLEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADME 860
Query: 473 AEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQK 652
A+ + +R+ A+ +L E ++ + K + RL E + +E L K
Sbjct: 861 AKFREKDEREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERD--VEELQLK 918
Query: 653 VVALEKTKQRLATEVEDLQLEVDR 724
+ + L +ED+ ++ ++
Sbjct: 919 LTKANENASFLQKSIEDMTVKAEQ 942
Score = 37.5 bits (83), Expect = 0.054
Identities = 60/261 (22%), Positives = 115/261 (44%), Gaps = 32/261 (12%)
Frame = +2
Query: 23 SDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSN--EKAAQEKI--VKQLQHQ- 187
+++ + + +++ + R + V +L A +D L E A +EK+ + QL+ +
Sbjct: 376 AEVAKATSHVGEIEQELALARDGHDQHVLELEAKMDQLRTMVEAADREKVELLNQLEEEK 435
Query: 188 --LNEVQSKADEANRTLNDLDAA-----------KKKLSI---ENSDLLRQLE------E 301
+ ++Q + +E + T DL+ A +K L++ E ++L R+LE +
Sbjct: 436 RKVEDLQFRVEEESITKGDLEVATVSEKSRIMELEKDLALRVQEVAELRRRLESNKPAGD 495
Query: 302 AESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLG-KFRNLEHDLDNIREQVEEEAE 478
+ +S L +I SL +LE T+ E G + + ++ + E+ ++
Sbjct: 496 VDMSLSLLQEIS-SLQEKLEVTRTDHQREITSLKEHFGAREETHQKEIKALYTATEKLSK 554
Query: 479 GKADLQRQLSKANAEAQ----LWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLN 646
L+ +L AN E LW+SK E+ + + +EE K L ET E
Sbjct: 555 ENESLKSKLEHANKENSDVIALWKSKLETAIASHQQAMEELKVSFSKGL--GAETAEFAE 612
Query: 647 QKVVALEKTKQRLATEVEDLQ 709
K +EK + E+E+LQ
Sbjct: 613 LK-TQIEKMRLDYQHEIENLQ 632
Score = 37.1 bits (82), Expect = 0.071
Identities = 36/176 (20%), Positives = 86/176 (48%), Gaps = 3/176 (1%)
Frame = +2
Query: 176 LQHQLNEVQSKADE--ANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLT 349
LQ L E Q ++ A R L + AK + ++ ++L A Q + L
Sbjct: 353 LQEALKEKQQHIEQLLAERDLERAEVAKATSHV--GEIEQELALARDGHDQHV---LELE 407
Query: 350 TQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQ 529
+++ + + + RE+ LL + + +++++ +VEEE+ K DL +++ + +++
Sbjct: 408 AKMDQLRTMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDL--EVATVSEKSR 465
Query: 530 LWRSKYESEGVARSEELEEAKRKLQARLAEAEETIE-SLNQKVVALEKTKQRLATE 694
+ + E + R +E+ E +R+L++ + + SL Q++ +L++ + T+
Sbjct: 466 I--MELEKDLALRVQEVAELRRRLESNKPAGDVDMSLSLLQEISSLQEKLEVTRTD 519
>BC033088-1|AAH33088.1| 465|Homo sapiens LMNA protein protein.
Length = 465
Score = 56.4 bits (130), Expect = 1e-07
Identities = 48/200 (24%), Positives = 103/200 (51%), Gaps = 9/200 (4%)
Frame = +2
Query: 152 AQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSK 331
++E + +++ +++ +A +TL+ + + +L +E S + + +E ++ ++
Sbjct: 66 SEEVVSREVSGIKAAYEAELGDARKTLDSVAKERARLQLELSKVREEFKELKACNTKKEG 125
Query: 332 IKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVE--EEAEGKADLQRQ- 502
++ +L+D + L + + +T L + R LE +L ++R QV E A G+A Q Q
Sbjct: 126 DLIAAQARLKDLEALLNSKEAALSTALSEKRTLEGELHDLRGQVAKLEAALGEAKKQLQD 185
Query: 503 --LSKANAEAQLWRSKYESEGVAR--SEELEEAKRKLQARLAEAE--ETIESLNQKVVAL 664
L + +AE +L K E + SEEL E KR+ + RL E + + E ++ AL
Sbjct: 186 EMLRRVDAENRLQTMKEELDFQKNIYSEELRETKRRHETRLVEIDNGKQREFESRLADAL 245
Query: 665 EKTKQRLATEVEDLQLEVDR 724
++ + + +VE + E+++
Sbjct: 246 QELRAQHEDQVEQYKKELEK 265
Score = 34.3 bits (75), Expect = 0.50
Identities = 31/144 (21%), Positives = 62/144 (43%), Gaps = 1/144 (0%)
Frame = +2
Query: 128 DHLSNEKAAQEKIVKQLQHQLNEVQS-KADEANRTLNDLDAAKKKLSIENSDLLRQLEEA 304
D L +A E V+Q + +L + S K D A ++ + + + +L +
Sbjct: 243 DALQELRAQHEDQVEQYKKELEKTYSAKLDNARQSA---ERNSNLVGAAHEELQQSRIRI 299
Query: 305 ESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGK 484
+S +QLS+++ L + + L D ARER T E ++ +R +++++ +
Sbjct: 300 DSLSAQLSQLQKQLAAKEAKLRDLEDSLARERDTSRRLLAEKEREMAEMRARMQQQLDEY 359
Query: 485 ADLQRQLSKANAEAQLWRSKYESE 556
+L + E +R E E
Sbjct: 360 QELLDIKLALDMEIHAYRKLLEGE 383
>AL645502-1|CAH70064.1| 976|Homo sapiens synaptonemal complex protein
1 protein.
Length = 976
Score = 56.4 bits (130), Expect = 1e-07
Identities = 50/207 (24%), Positives = 95/207 (45%), Gaps = 3/207 (1%)
Frame = +2
Query: 101 EVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSD 280
EV+DL L ++ + K VK L+ +L + K E N L K+L+ E SD
Sbjct: 477 EVHDLEIQLTAITTSEQYYSKEVKDLKTELENEKLKNTELTSHCNKLSLENKELTQETSD 536
Query: 281 LLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQ 460
+ +L+ + ++ K + + Q+E+ L + E + R L L+ D ++ +
Sbjct: 537 MTLELKNQQEDINNNKKQEERMLKQIEN---LQETETQLRNELEYVREELKQKRDEVKCK 593
Query: 461 VEEEAEGKADLQRQLSKAN---AEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEET 631
+++ E +L++Q+ N E Q + +G A S++L + K+ + E
Sbjct: 594 LDKSEENCNNLRKQVENKNKYIEELQQENKALKKKGTAESKQLNVYEIKVN----KLELE 649
Query: 632 IESLNQKVVALEKTKQRLATEVEDLQL 712
+ES QK + T Q+ E+ED ++
Sbjct: 650 LESAKQKFGEITDTYQK---EIEDKKI 673
Score = 40.3 bits (90), Expect = 0.008
Identities = 39/232 (16%), Positives = 100/232 (43%), Gaps = 3/232 (1%)
Frame = +2
Query: 38 QLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADE 217
+L+++ KL E E+ + + L E EKI ++L+ E+
Sbjct: 418 ELEEMTKLTNNKEVE----LEELKKVLGEKETLLYENKQFEKIAEELKGTEQELIGLLQA 473
Query: 218 ANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARE 397
+ ++DL+ ++ +++++ ++++ LT+ E +E
Sbjct: 474 REKEVHDLEIQLTAITTSEQYYSKEVKDLKTELENEKLKNTELTSHCNKLSLENKELTQE 533
Query: 398 RATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYE---SEGVAR 568
+ + + +N + D++N ++Q E + +LQ ++ E + R + + E +
Sbjct: 534 TSDMTLELKNQQEDINNNKKQEERMLKQIENLQETETQLRNELEYVREELKQKRDEVKCK 593
Query: 569 SEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
++ EE L+ ++ + IE L Q+ AL+K + ++ +++V++
Sbjct: 594 LDKSEENCNNLRKQVENKNKYIEELQQENKALKKKGTAESKQLNVYEIKVNK 645
Score = 36.3 bits (80), Expect = 0.12
Identities = 54/212 (25%), Positives = 91/212 (42%), Gaps = 22/212 (10%)
Frame = +2
Query: 146 KAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQL 325
K EKI Q E+ K + + L + + K+ DL LEE+ +V+QL
Sbjct: 244 KEDYEKIQHLEQEYKKEINDKEKQVSLLLIQITEKENKMK----DLTFLLEESRDKVNQL 299
Query: 326 SK--------IKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEG 481
+ +K S+ Q TK L D + + ++ + + LE DL + + + E
Sbjct: 300 EEKTKLQSENLKQSIEKQHHLTKELEDIKVSLQRSVSTQ-KALEEDLQIATKTICQLTEE 358
Query: 482 KADLQRQLSKANAEAQLWRSKYES-----EGVARSE---------ELEEAKRKLQARLAE 619
K + +KA A +++E+ E + R+E +L+ +LQ + +E
Sbjct: 359 KETQMEESNKARAAHSFVVTEFETTVCSLEELLRTEQQRLEKNEDQLKILTMELQKKSSE 418
Query: 620 AEETIESLNQKVVALEKTKQRLATEVEDLQLE 715
EE + N K V LE+ K+ L E E L E
Sbjct: 419 LEEMTKLTNNKEVELEELKKVLG-EKETLLYE 449
Score = 34.7 bits (76), Expect = 0.38
Identities = 34/204 (16%), Positives = 91/204 (44%), Gaps = 3/204 (1%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSK-A 211
E NKL + ++ + +L+ + ++N K +E+++KQ+++ L E +++
Sbjct: 515 ELTSHCNKLSLENKELTQETSDMTLELKNQQEDINNNKKQEERMLKQIEN-LQETETQLR 573
Query: 212 DEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEA 391
+E +L + ++ + QV +K L + + K+ E+
Sbjct: 574 NELEYVREELKQKRDEVKCKLDKSEENCNNLRKQVENKNKYIEELQQENKALKKKGTAES 633
Query: 392 RERATLLGKFRNLEHDLDNIREQVEE--EAEGKADLQRQLSKANAEAQLWRSKYESEGVA 565
++ K LE +L++ +++ E + K +++S+ N ++ ++K ++
Sbjct: 634 KQLNVYEIKVNKLELELESAKQKFGEITDTYQKEIEDKKISEENLLEEVEKAKVIADEAV 693
Query: 566 RSEELEEAKRKLQARLAEAEETIE 637
+ + +E ++ Q ++AE +E
Sbjct: 694 KLQ--KEIDKRCQHKIAEMVALME 715
>AL358372-3|CAH72848.1| 792|Homo sapiens synaptonemal complex protein
1 protein.
Length = 792
Score = 56.4 bits (130), Expect = 1e-07
Identities = 50/207 (24%), Positives = 95/207 (45%), Gaps = 3/207 (1%)
Frame = +2
Query: 101 EVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSD 280
EV+DL L ++ + K VK L+ +L + K E N L K+L+ E SD
Sbjct: 477 EVHDLEIQLTAITTSEQYYSKEVKDLKTELENEKLKNTELTSHCNKLSLENKELTQETSD 536
Query: 281 LLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQ 460
+ +L+ + ++ K + + Q+E+ L + E + R L L+ D ++ +
Sbjct: 537 MTLELKNQQEDINNNKKQEERMLKQIEN---LQETETQLRNELEYVREELKQKRDEVKCK 593
Query: 461 VEEEAEGKADLQRQLSKAN---AEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEET 631
+++ E +L++Q+ N E Q + +G A S++L + K+ + E
Sbjct: 594 LDKSEENCNNLRKQVENKNKYIEELQQENKALKKKGTAESKQLNVYEIKVN----KLELE 649
Query: 632 IESLNQKVVALEKTKQRLATEVEDLQL 712
+ES QK + T Q+ E+ED ++
Sbjct: 650 LESAKQKFGEITDTYQK---EIEDKKI 673
Score = 40.3 bits (90), Expect = 0.008
Identities = 39/232 (16%), Positives = 100/232 (43%), Gaps = 3/232 (1%)
Frame = +2
Query: 38 QLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADE 217
+L+++ KL E E+ + + L E EKI ++L+ E+
Sbjct: 418 ELEEMTKLTNNKEVE----LEELKKVLGEKETLLYENKQFEKIAEELKGTEQELIGLLQA 473
Query: 218 ANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARE 397
+ ++DL+ ++ +++++ ++++ LT+ E +E
Sbjct: 474 REKEVHDLEIQLTAITTSEQYYSKEVKDLKTELENEKLKNTELTSHCNKLSLENKELTQE 533
Query: 398 RATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYE---SEGVAR 568
+ + + +N + D++N ++Q E + +LQ ++ E + R + + E +
Sbjct: 534 TSDMTLELKNQQEDINNNKKQEERMLKQIENLQETETQLRNELEYVREELKQKRDEVKCK 593
Query: 569 SEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
++ EE L+ ++ + IE L Q+ AL+K + ++ +++V++
Sbjct: 594 LDKSEENCNNLRKQVENKNKYIEELQQENKALKKKGTAESKQLNVYEIKVNK 645
Score = 36.3 bits (80), Expect = 0.12
Identities = 54/212 (25%), Positives = 91/212 (42%), Gaps = 22/212 (10%)
Frame = +2
Query: 146 KAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQL 325
K EKI Q E+ K + + L + + K+ DL LEE+ +V+QL
Sbjct: 244 KEDYEKIQHLEQEYKKEINDKEKQVSLLLIQITEKENKMK----DLTFLLEESRDKVNQL 299
Query: 326 SK--------IKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEG 481
+ +K S+ Q TK L D + + ++ + + LE DL + + + E
Sbjct: 300 EEKTKLQSENLKQSIEKQHHLTKELEDIKVSLQRSVSTQ-KALEEDLQIATKTICQLTEE 358
Query: 482 KADLQRQLSKANAEAQLWRSKYES-----EGVARSE---------ELEEAKRKLQARLAE 619
K + +KA A +++E+ E + R+E +L+ +LQ + +E
Sbjct: 359 KETQMEESNKARAAHSFVVTEFETTVCSLEELLRTEQQRLEKNEDQLKILTMELQKKSSE 418
Query: 620 AEETIESLNQKVVALEKTKQRLATEVEDLQLE 715
EE + N K V LE+ K+ L E E L E
Sbjct: 419 LEEMTKLTNNKEVELEELKKVLG-EKETLLYE 449
Score = 34.7 bits (76), Expect = 0.38
Identities = 34/204 (16%), Positives = 91/204 (44%), Gaps = 3/204 (1%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSK-A 211
E NKL + ++ + +L+ + ++N K +E+++KQ+++ L E +++
Sbjct: 515 ELTSHCNKLSLENKELTQETSDMTLELKNQQEDINNNKKQEERMLKQIEN-LQETETQLR 573
Query: 212 DEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEA 391
+E +L + ++ + QV +K L + + K+ E+
Sbjct: 574 NELEYVREELKQKRDEVKCKLDKSEENCNNLRKQVENKNKYIEELQQENKALKKKGTAES 633
Query: 392 RERATLLGKFRNLEHDLDNIREQVEE--EAEGKADLQRQLSKANAEAQLWRSKYESEGVA 565
++ K LE +L++ +++ E + K +++S+ N ++ ++K ++
Sbjct: 634 KQLNVYEIKVNKLELELESAKQKFGEITDTYQKEIEDKKISEENLLEEVEKAKVIADEAV 693
Query: 566 RSEELEEAKRKLQARLAEAEETIE 637
+ + +E ++ Q ++AE +E
Sbjct: 694 KLQ--KEIDKRCQHKIAEMVALME 715
>AL358372-2|CAH72847.1| 976|Homo sapiens synaptonemal complex protein
1 protein.
Length = 976
Score = 56.4 bits (130), Expect = 1e-07
Identities = 50/207 (24%), Positives = 95/207 (45%), Gaps = 3/207 (1%)
Frame = +2
Query: 101 EVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSD 280
EV+DL L ++ + K VK L+ +L + K E N L K+L+ E SD
Sbjct: 477 EVHDLEIQLTAITTSEQYYSKEVKDLKTELENEKLKNTELTSHCNKLSLENKELTQETSD 536
Query: 281 LLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQ 460
+ +L+ + ++ K + + Q+E+ L + E + R L L+ D ++ +
Sbjct: 537 MTLELKNQQEDINNNKKQEERMLKQIEN---LQETETQLRNELEYVREELKQKRDEVKCK 593
Query: 461 VEEEAEGKADLQRQLSKAN---AEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEET 631
+++ E +L++Q+ N E Q + +G A S++L + K+ + E
Sbjct: 594 LDKSEENCNNLRKQVENKNKYIEELQQENKALKKKGTAESKQLNVYEIKVN----KLELE 649
Query: 632 IESLNQKVVALEKTKQRLATEVEDLQL 712
+ES QK + T Q+ E+ED ++
Sbjct: 650 LESAKQKFGEITDTYQK---EIEDKKI 673
Score = 40.3 bits (90), Expect = 0.008
Identities = 39/232 (16%), Positives = 100/232 (43%), Gaps = 3/232 (1%)
Frame = +2
Query: 38 QLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADE 217
+L+++ KL E E+ + + L E EKI ++L+ E+
Sbjct: 418 ELEEMTKLTNNKEVE----LEELKKVLGEKETLLYENKQFEKIAEELKGTEQELIGLLQA 473
Query: 218 ANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARE 397
+ ++DL+ ++ +++++ ++++ LT+ E +E
Sbjct: 474 REKEVHDLEIQLTAITTSEQYYSKEVKDLKTELENEKLKNTELTSHCNKLSLENKELTQE 533
Query: 398 RATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYE---SEGVAR 568
+ + + +N + D++N ++Q E + +LQ ++ E + R + + E +
Sbjct: 534 TSDMTLELKNQQEDINNNKKQEERMLKQIENLQETETQLRNELEYVREELKQKRDEVKCK 593
Query: 569 SEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
++ EE L+ ++ + IE L Q+ AL+K + ++ +++V++
Sbjct: 594 LDKSEENCNNLRKQVENKNKYIEELQQENKALKKKGTAESKQLNVYEIKVNK 645
Score = 36.3 bits (80), Expect = 0.12
Identities = 54/212 (25%), Positives = 91/212 (42%), Gaps = 22/212 (10%)
Frame = +2
Query: 146 KAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQL 325
K EKI Q E+ K + + L + + K+ DL LEE+ +V+QL
Sbjct: 244 KEDYEKIQHLEQEYKKEINDKEKQVSLLLIQITEKENKMK----DLTFLLEESRDKVNQL 299
Query: 326 SK--------IKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEG 481
+ +K S+ Q TK L D + + ++ + + LE DL + + + E
Sbjct: 300 EEKTKLQSENLKQSIEKQHHLTKELEDIKVSLQRSVSTQ-KALEEDLQIATKTICQLTEE 358
Query: 482 KADLQRQLSKANAEAQLWRSKYES-----EGVARSE---------ELEEAKRKLQARLAE 619
K + +KA A +++E+ E + R+E +L+ +LQ + +E
Sbjct: 359 KETQMEESNKARAAHSFVVTEFETTVCSLEELLRTEQQRLEKNEDQLKILTMELQKKSSE 418
Query: 620 AEETIESLNQKVVALEKTKQRLATEVEDLQLE 715
EE + N K V LE+ K+ L E E L E
Sbjct: 419 LEEMTKLTNNKEVELEELKKVLG-EKETLLYE 449
Score = 34.7 bits (76), Expect = 0.38
Identities = 34/204 (16%), Positives = 91/204 (44%), Gaps = 3/204 (1%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSK-A 211
E NKL + ++ + +L+ + ++N K +E+++KQ+++ L E +++
Sbjct: 515 ELTSHCNKLSLENKELTQETSDMTLELKNQQEDINNNKKQEERMLKQIEN-LQETETQLR 573
Query: 212 DEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEA 391
+E +L + ++ + QV +K L + + K+ E+
Sbjct: 574 NELEYVREELKQKRDEVKCKLDKSEENCNNLRKQVENKNKYIEELQQENKALKKKGTAES 633
Query: 392 RERATLLGKFRNLEHDLDNIREQVEE--EAEGKADLQRQLSKANAEAQLWRSKYESEGVA 565
++ K LE +L++ +++ E + K +++S+ N ++ ++K ++
Sbjct: 634 KQLNVYEIKVNKLELELESAKQKFGEITDTYQKEIEDKKISEENLLEEVEKAKVIADEAV 693
Query: 566 RSEELEEAKRKLQARLAEAEETIE 637
+ + +E ++ Q ++AE +E
Sbjct: 694 KLQ--KEIDKRCQHKIAEMVALME 715
>AF273043-1|AAG34903.1| 795|Homo sapiens CTCL tumor antigen se2-1
protein.
Length = 795
Score = 56.4 bits (130), Expect = 1e-07
Identities = 50/207 (24%), Positives = 95/207 (45%), Gaps = 3/207 (1%)
Frame = +2
Query: 101 EVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSD 280
EV+DL L ++ + K VK L+ +L + K E N L K+L+ E SD
Sbjct: 477 EVHDLEIQLTAITTSEQYYSKEVKDLKTELENEKLKNTELTSHCNKLSLENKELTQETSD 536
Query: 281 LLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQ 460
+ +L+ + ++ K + + Q+E+ L + E + R L L+ D ++ +
Sbjct: 537 MTLELKNQQEDINNNKKQEERMLKQIEN---LQETETQLRNELEYVREELKQKRDEVKCK 593
Query: 461 VEEEAEGKADLQRQLSKAN---AEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEET 631
+++ E +L++Q+ N E Q + +G A S++L + K+ + E
Sbjct: 594 LDKSEENCNNLRKQVENKNKYIEELQQENKALKKKGTAESKQLNVYEIKVN----KLELE 649
Query: 632 IESLNQKVVALEKTKQRLATEVEDLQL 712
+ES QK + T Q+ E+ED ++
Sbjct: 650 LESAKQKFGEITDTYQK---EIEDKKI 673
Score = 40.3 bits (90), Expect = 0.008
Identities = 39/232 (16%), Positives = 100/232 (43%), Gaps = 3/232 (1%)
Frame = +2
Query: 38 QLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADE 217
+L+++ KL E E+ + + L E EKI ++L+ E+
Sbjct: 418 ELEEMTKLTNNKEVE----LEELKKVLGEKETLLYENKQFEKIAEELKGTEQELIGLLQA 473
Query: 218 ANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARE 397
+ ++DL+ ++ +++++ ++++ LT+ E +E
Sbjct: 474 REKEVHDLEIQLTAITTSEQYYSKEVKDLKTELENEKLKNTELTSHCNKLSLENKELTQE 533
Query: 398 RATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYE---SEGVAR 568
+ + + +N + D++N ++Q E + +LQ ++ E + R + + E +
Sbjct: 534 TSDMTLELKNQQEDINNNKKQEERMLKQIENLQETETQLRNELEYVREELKQKRDEVKCK 593
Query: 569 SEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
++ EE L+ ++ + IE L Q+ AL+K + ++ +++V++
Sbjct: 594 LDKSEENCNNLRKQVENKNKYIEELQQENKALKKKGTAESKQLNVYEIKVNK 645
Score = 36.3 bits (80), Expect = 0.12
Identities = 54/212 (25%), Positives = 91/212 (42%), Gaps = 22/212 (10%)
Frame = +2
Query: 146 KAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQL 325
K EKI Q E+ K + + L + + K+ DL LEE+ +V+QL
Sbjct: 244 KEDYEKIQHLEQEYKKEINDKEKQVSLLLIQITEKENKMK----DLTFLLEESRDKVNQL 299
Query: 326 SK--------IKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEG 481
+ +K S+ Q TK L D + + ++ + + LE DL + + + E
Sbjct: 300 EEKTKLQSENLKQSIEKQHHLTKELEDIKVSLQRSVSTQ-KALEEDLQIATKTICQLTEE 358
Query: 482 KADLQRQLSKANAEAQLWRSKYES-----EGVARSE---------ELEEAKRKLQARLAE 619
K + +KA A +++E+ E + R+E +L+ +LQ + +E
Sbjct: 359 KETQMEESNKARAAHSFVVTEFETTVCSLEELLRTEQQRLEKNEDQLKILTMELQKKSSE 418
Query: 620 AEETIESLNQKVVALEKTKQRLATEVEDLQLE 715
EE + N K V LE+ K+ L E E L E
Sbjct: 419 LEEMTKLTNNKEVELEELKKVLG-EKETLLYE 449
Score = 34.7 bits (76), Expect = 0.38
Identities = 34/204 (16%), Positives = 91/204 (44%), Gaps = 3/204 (1%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSK-A 211
E NKL + ++ + +L+ + ++N K +E+++KQ+++ L E +++
Sbjct: 515 ELTSHCNKLSLENKELTQETSDMTLELKNQQEDINNNKKQEERMLKQIEN-LQETETQLR 573
Query: 212 DEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEA 391
+E +L + ++ + QV +K L + + K+ E+
Sbjct: 574 NELEYVREELKQKRDEVKCKLDKSEENCNNLRKQVENKNKYIEELQQENKALKKKGTAES 633
Query: 392 RERATLLGKFRNLEHDLDNIREQVEE--EAEGKADLQRQLSKANAEAQLWRSKYESEGVA 565
++ K LE +L++ +++ E + K +++S+ N ++ ++K ++
Sbjct: 634 KQLNVYEIKVNKLELELESAKQKFGEITDTYQKEIEDKKISEENLLEEVEKAKVIADEAV 693
Query: 566 RSEELEEAKRKLQARLAEAEETIE 637
+ + +E ++ Q ++AE +E
Sbjct: 694 KLQ--KEIDKRCQHKIAEMVALME 715
>AF229111-1|AAK00229.1| 1285|Homo sapiens myosin VI protein.
Length = 1285
Score = 56.4 bits (130), Expect = 1e-07
Identities = 44/180 (24%), Positives = 85/180 (47%), Gaps = 1/180 (0%)
Frame = +2
Query: 134 LSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQ 313
L + K K +K L+ ++ + +K T + L + +LL L++ + Q
Sbjct: 860 LKDGKPEMNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYDALVKSSEELLSALQKKKQQ 919
Query: 314 VSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADL 493
+ +++ ++ KR ++E R R + R ++ +++ R+Q EEE + + D
Sbjct: 920 EEEAERLRRIQEEMEKERKRREEDEKRRRKE--EEERRMKLEMEAKRKQEEEERKXREDD 977
Query: 494 QRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAE-ETIESLNQKVVALEK 670
++++ +A EAQL R K E E E R+L R+A++E E I Q +AL +
Sbjct: 978 EKRI-QAEVEAQLARQKEEESQQQAVLEQERRDRELALRIAQSEAELISDEAQADLALRR 1036
>U51587-1|AAB81549.1| 767|Homo sapiens Golgi complex autoantigen
golgin-97 protein.
Length = 767
Score = 56.0 bits (129), Expect = 1e-07
Identities = 49/213 (23%), Positives = 97/213 (45%), Gaps = 4/213 (1%)
Frame = +2
Query: 5 SAGRFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQH 184
++ + SD+ ++L++L + + E+ R + + + L ++ + +++QL
Sbjct: 218 NSNQMSSDLSQKLEELQRHYSTLEEQRDHVIASKTGAESKITALEQKEQELQALIQQLSI 277
Query: 185 QLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLED 364
L +V ++ E + L +K S+E L Q E V +L K K LED
Sbjct: 278 DLQKVTAETQEKEDVITHLQ--EKVASLEKR--LEQNLSGEEHVQELLKEKTLAEQNLED 333
Query: 365 TKR--LADEEARERA--TLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQL 532
T++ LA ++ +A TL + R LE L EQ+ ++++G Q + A A
Sbjct: 334 TRQQLLAARSSQAKAINTLETRVRELEQTLQASEEQL-QQSKGIVAAQETQIQELAAANQ 392
Query: 533 WRSKYESEGVARSEELEEAKRKLQARLAEAEET 631
S + + +A ++ E + L+A++ E T
Sbjct: 393 ESSHVQQQALALEQQFLERTQALEAQIVALERT 425
Score = 45.2 bits (102), Expect = 3e-04
Identities = 53/222 (23%), Positives = 101/222 (45%), Gaps = 14/222 (6%)
Frame = +2
Query: 101 EVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSD 280
++ L A L + + +KI ++L+ L + Q + + N+ A + E
Sbjct: 66 QIRKLEARLSDYAEQVRNLQKIKEKLEIALEKHQDSSMRKFQEQNETFQANRAKMAEGLA 125
Query: 281 LL--RQLEEAESQVSQLSKIKVSLTTQLEDTKRLADE--EARERATLLGKFRNLEHDLDN 448
L R+ +E ++ QL K K LT QL++ K + + R+ L F+ + +L
Sbjct: 126 LALARKDQEWSEKMDQLEKEKNILTAQLQEMKNQSMNLFQRRDEMDELEGFQ--QQELSK 183
Query: 449 IREQV--EEEAEGKADLQ-----RQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQA 607
I+ + +EE+ GK + + R+LS+ E L S S + S++LEE +R
Sbjct: 184 IKHMLLKKEESLGKMEQELEARTRELSRTQEE--LMNSNQMSSDL--SQKLEELQRHYST 239
Query: 608 RLAEAEETIES---LNQKVVALEKTKQRLATEVEDLQLEVDR 724
+ + I S K+ ALE+ +Q L ++ L +++ +
Sbjct: 240 LEEQRDHVIASKTGAESKITALEQKEQELQALIQQLSIDLQK 281
>BC146764-1|AAI46765.1| 1285|Homo sapiens myosin VI protein.
Length = 1285
Score = 56.0 bits (129), Expect = 1e-07
Identities = 44/180 (24%), Positives = 85/180 (47%), Gaps = 1/180 (0%)
Frame = +2
Query: 134 LSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQ 313
L + K K +K L+ ++ + +K T + L + +LL L++ + Q
Sbjct: 860 LKDGKPEMNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYDALVKSSEELLSALQKKKQQ 919
Query: 314 VSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADL 493
+ +++ ++ KR ++E R R + R ++ +++ R+Q EEE + + D
Sbjct: 920 EEEAERLRRIQEEMEKERKRREEDEKRRRKE--EEERRMKLEMEAKRKQEEEERKKREDD 977
Query: 494 QRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAE-ETIESLNQKVVALEK 670
++++ +A EAQL R K E E E R+L R+A++E E I Q +AL +
Sbjct: 978 EKRI-QAEVEAQLARQKEEESQQQAVLEQERRDRELALRIAQSEAELISDEAQADLALRR 1036
>BC032853-1|AAH32853.1| 767|Homo sapiens golgi autoantigen, golgin
subfamily a, 1 protein.
Length = 767
Score = 56.0 bits (129), Expect = 1e-07
Identities = 59/255 (23%), Positives = 116/255 (45%), Gaps = 15/255 (5%)
Frame = +2
Query: 5 SAGRFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQH 184
++ + SD+ ++L++L + + E+ R + + + L ++ + +++QL
Sbjct: 218 NSNQMSSDLSQKLEELQRHYSTLEEQRDHVIASKTGAESKITALEQKEQELQALIQQLSI 277
Query: 185 QLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLED 364
L +V ++ E + L +K S+E L Q E V +L K K LED
Sbjct: 278 DLQKVTAETQEKEDVITHLQ--EKVASLEKR--LEQNLSGEEHVQELLKEKTLAEQNLED 333
Query: 365 TKR--LADEEARERA--TLLGKFRNLEHDLDNIREQVEEE----AEGKADLQRQLSKANA 520
T++ LA ++ +A TL + R LE L EQ+++ A + +Q +L+ AN
Sbjct: 334 TRQQLLAARSSQAKAINTLETRVRELEQTLQASEEQLQQSKGIVAAQETQIQ-ELAAANQ 392
Query: 521 EA---QLWRSKYESEGVARSEELE----EAKRKLQARLAEAEETIESLNQKVVALEKTKQ 679
E+ Q E + + R++ LE +R A AE+ + L Q+ AL++ +
Sbjct: 393 ESSHVQQQALALEQQFLERTQALEAQIVALERMRAADQTTAEQGMRQLEQENAALKECRN 452
Query: 680 RLATEVEDLQLEVDR 724
+++ Q E+ +
Sbjct: 453 EYERSLQNHQFELKK 467
Score = 45.2 bits (102), Expect = 3e-04
Identities = 53/222 (23%), Positives = 101/222 (45%), Gaps = 14/222 (6%)
Frame = +2
Query: 101 EVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSD 280
++ L A L + + +KI ++L+ L + Q + + N+ A + E
Sbjct: 66 QIRKLEARLSDYAEQVRNLQKIKEKLEIALEKHQDSSMRKFQEQNETFQANRAKMAEGLA 125
Query: 281 LL--RQLEEAESQVSQLSKIKVSLTTQLEDTKRLADE--EARERATLLGKFRNLEHDLDN 448
L R+ +E ++ QL K K LT QL++ K + + R+ L F+ + +L
Sbjct: 126 LALARKDQEWSEKMDQLEKEKNILTAQLQEMKNQSMNLFQRRDEMDELEGFQ--QQELSK 183
Query: 449 IREQV--EEEAEGKADLQ-----RQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQA 607
I+ + +EE+ GK + + R+LS+ E L S S + S++LEE +R
Sbjct: 184 IKHMLLKKEESLGKMEQELEARTRELSRTQEE--LMNSNQMSSDL--SQKLEELQRHYST 239
Query: 608 RLAEAEETIES---LNQKVVALEKTKQRLATEVEDLQLEVDR 724
+ + I S K+ ALE+ +Q L ++ L +++ +
Sbjct: 240 LEEQRDHVIASKTGAESKITALEQKEQELQALIQQLSIDLQK 281
>AL136093-2|CAI42825.1| 1285|Homo sapiens myosin VI protein.
Length = 1285
Score = 56.0 bits (129), Expect = 1e-07
Identities = 44/180 (24%), Positives = 85/180 (47%), Gaps = 1/180 (0%)
Frame = +2
Query: 134 LSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQ 313
L + K K +K L+ ++ + +K T + L + +LL L++ + Q
Sbjct: 860 LKDGKPEMNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYDALVKSSEELLSALQKKKQQ 919
Query: 314 VSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADL 493
+ +++ ++ KR ++E R R + R ++ +++ R+Q EEE + + D
Sbjct: 920 EEEAERLRRIQEEMEKERKRREEDEKRRRKE--EEERRMKLEMEAKRKQEEEERKKREDD 977
Query: 494 QRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAE-ETIESLNQKVVALEK 670
++++ +A EAQL R K E E E R+L R+A++E E I Q +AL +
Sbjct: 978 EKRI-QAEVEAQLARQKEEESQQQAVLEQERRDRELALRIAQSEAELISDEAQADLALRR 1036
>AL109897-1|CAI19521.1| 1285|Homo sapiens myosin VI protein.
Length = 1285
Score = 56.0 bits (129), Expect = 1e-07
Identities = 44/180 (24%), Positives = 85/180 (47%), Gaps = 1/180 (0%)
Frame = +2
Query: 134 LSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQ 313
L + K K +K L+ ++ + +K T + L + +LL L++ + Q
Sbjct: 860 LKDGKPEMNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYDALVKSSEELLSALQKKKQQ 919
Query: 314 VSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADL 493
+ +++ ++ KR ++E R R + R ++ +++ R+Q EEE + + D
Sbjct: 920 EEEAERLRRIQEEMEKERKRREEDEKRRRKE--EEERRMKLEMEAKRKQEEEERKKREDD 977
Query: 494 QRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAE-ETIESLNQKVVALEK 670
++++ +A EAQL R K E E E R+L R+A++E E I Q +AL +
Sbjct: 978 EKRI-QAEVEAQLARQKEEESQQQAVLEQERRDRELALRIAQSEAELISDEAQADLALRR 1036
>AF041004-1|AAD17459.1| 1756|Homo sapiens periplakin protein.
Length = 1756
Score = 56.0 bits (129), Expect = 1e-07
Identities = 58/242 (23%), Positives = 110/242 (45%), Gaps = 15/242 (6%)
Frame = +2
Query: 44 DQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEAN 223
++L+++K + + + E LRA + + + + +L+ +L +Q + E
Sbjct: 1341 EELSRVKERVVQQEVVRYEEEPGLRAEASAFAESIDVELRQIDKLRAELRRLQRRRTELE 1400
Query: 224 RTLNDLDA---AKKKLSIENSDLLRQL-----EEAESQVSQLSKIKVSLTTQLEDTKRLA 379
R L +L+ A+++ E L ++L EEAE++ KV L + + A
Sbjct: 1401 RQLEELERERQARREAEREVQRLQQRLAALEQEEAEAREKVTHTQKVVLQQDPQQAREHA 1460
Query: 380 ------DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRS 541
+EE R L G+ L L + E+ E + + Q+ K + E ++ R
Sbjct: 1461 LLRLQLEEEQHRRQLLEGELETLRRKLAAL-EKAEVKEKVVLSESVQVEKGDTEQEIQRL 1519
Query: 542 KYESEGVARSE-ELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEV 718
K E +RS+ EL+ +L+ARL+E E ++++ L + +L E ++LQLE
Sbjct: 1520 KSSLEEESRSKRELDVEVSRLEARLSELEFHNSKSSKELDFLREENHKLQLERQNLQLET 1579
Query: 719 DR 724
R
Sbjct: 1580 RR 1581
Score = 39.1 bits (87), Expect = 0.018
Identities = 56/256 (21%), Positives = 115/256 (44%), Gaps = 28/256 (10%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEK--AAQEKIVKQLQHQLNEVQSK 208
E QL + A+ + E+ L+ L L E QE +VK++ ++ +++
Sbjct: 948 ESFQQLQRTLAEEQHKNQLLQEELEALQLQLRALEQETRDGGQEYVVKEVL-RIEPDRAQ 1006
Query: 209 ADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEE 388
ADE + +L+A +++ +++L + + + S+ + +T + + +L ++
Sbjct: 1007 ADEVLQLREELEALRRQKGAREAEVLLLQQRVAALAEEKSRAQEKVTEK--EVVKLQNDP 1064
Query: 389 ARERATLLGKFRNLEHD---LDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYE--- 550
E +++ L+ D D +RE+ EEE D ++L K A A+ + E
Sbjct: 1065 QLE-----AEYQQLQEDHQRQDQLREKQEEELSFLQDKLKRLEKERAMAEGKITVKEVLK 1119
Query: 551 -SEGVARSEELEEAKRKLQ-----ARLAEAEET--------IESLNQKVVALEKTKQ--- 679
+ A E+ + R+ + AR ++ E+T +E N KVV EK ++
Sbjct: 1120 VEKDAATEREVSDLTRQYEDEAAKARASQREKTELLRKIWALEEENAKVVVQEKVREIVR 1179
Query: 680 ---RLATEVEDLQLEV 718
+ +EV +L+LE+
Sbjct: 1180 PDPKAESEVANLRLEL 1195
Score = 38.7 bits (86), Expect = 0.023
Identities = 43/194 (22%), Positives = 87/194 (44%)
Frame = +2
Query: 134 LSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQ 313
L N+K ++I + Q ++ ++ + + + + + D + +KL LL S
Sbjct: 767 LKNQKNLLDEIASREQ-EVQKICANSQQYQQAVKDYELEAEKLR----SLLDLENGRSSH 821
Query: 314 VSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADL 493
VS+ ++++ T E+ LA + A + +NLE L+ +R+Q E E + L
Sbjct: 822 VSKRARLQSPATKVKEEEAALAAKFTEVYAINRQRLQNLEFALNLLRQQPEVEVTHET-L 880
Query: 494 QRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKT 673
QR + E + W+ + E +E E +R+L+ + +E I +L +
Sbjct: 881 QRNRPDSGVE-EAWKIRKE------LDEETERRRQLENEVKSTQEEIWTLRNQGPQESVV 933
Query: 674 KQRLATEVEDLQLE 715
++ + +V D LE
Sbjct: 934 RKEVLKKVPDPVLE 947
Score = 38.7 bits (86), Expect = 0.023
Identities = 26/93 (27%), Positives = 46/93 (49%), Gaps = 8/93 (8%)
Frame = +2
Query: 449 IREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEEL--------EEAKRKLQ 604
IR++++EE E + L+ ++ E R++ E V R E L EE+ ++LQ
Sbjct: 895 IRKELDEETERRRQLENEVKSTQEEIWTLRNQGPQESVVRKEVLKKVPDPVLEESFQQLQ 954
Query: 605 ARLAEAEETIESLNQKVVALEKTKQRLATEVED 703
LAE + + L +++ AL+ + L E D
Sbjct: 955 RTLAEEQHKNQLLQEELEALQLQLRALEQETRD 987
Score = 31.5 bits (68), Expect = 3.5
Identities = 50/210 (23%), Positives = 92/210 (43%), Gaps = 6/210 (2%)
Frame = +2
Query: 113 LRAGLDHLSNEKAAQEK-IVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLR 289
L AGLD ++++ QEK I L+ L + ++ D A R + + + L IE + R
Sbjct: 507 LLAGLDKVASDLDRQEKAITGILRPPLEQGRAVQDSAERAKDLKNITNELLRIE-PEKTR 565
Query: 290 QLEEAESQVSQL--SKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQV 463
E E+ + L S L T++EDT R + LL + + + + +
Sbjct: 566 STAEGEAFIQALPGSGTTPLLRTRVEDTNR----KYEHLLQLLDLAQEKVDVANRLEKSL 621
Query: 464 EEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQAR---LAEAEETI 634
++ E A + L++ + + R +S+G +EL +LQA+ L E E+ +
Sbjct: 622 QQSWELLATHENHLNQDDTVPESSR-VLDSKG----QELAPMACELQAQKSLLGEVEQNL 676
Query: 635 ESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
++ Q L Q ++E + EV +
Sbjct: 677 QAAKQCSSTLASRFQEHCPDLERQEAEVHK 706
>AF013717-1|AAC39668.1| 1756|Homo sapiens periplakin protein.
Length = 1756
Score = 56.0 bits (129), Expect = 1e-07
Identities = 58/242 (23%), Positives = 110/242 (45%), Gaps = 15/242 (6%)
Frame = +2
Query: 44 DQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEAN 223
++L+++K + + + E LRA + + + + +L+ +L +Q + E
Sbjct: 1341 EELSRVKERVVQQEVVRYEEEPGLRAEASAFAESIDVELRQIDKLRAELRRLQRRRTELE 1400
Query: 224 RTLNDLDA---AKKKLSIENSDLLRQL-----EEAESQVSQLSKIKVSLTTQLEDTKRLA 379
R L +L+ A+++ E L ++L EEAE++ KV L + + A
Sbjct: 1401 RQLEELERERQARREAEREVQRLQQRLAALEQEEAEAREKVTHTQKVVLQQDPQQAREHA 1460
Query: 380 ------DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRS 541
+EE R L G+ L L + E+ E + + Q+ K + E ++ R
Sbjct: 1461 LLRLQLEEEQHRRQLLEGELETLRRKLAAL-EKAEVKEKVVLSESVQVEKGDTEQEIQRL 1519
Query: 542 KYESEGVARSE-ELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEV 718
K E +RS+ EL+ +L+ARL+E E ++++ L + +L E ++LQLE
Sbjct: 1520 KSSLEEESRSKRELDVEVSRLEARLSELEFHNSKSSKELDFLREENHKLQLERQNLQLET 1579
Query: 719 DR 724
R
Sbjct: 1580 RR 1581
Score = 39.1 bits (87), Expect = 0.018
Identities = 56/256 (21%), Positives = 115/256 (44%), Gaps = 28/256 (10%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEK--AAQEKIVKQLQHQLNEVQSK 208
E QL + A+ + E+ L+ L L E QE +VK++ ++ +++
Sbjct: 948 ESFQQLQRTLAEEQHKNQLLQEELEALQLQLRALEQETRDGGQEYVVKEVL-RIEPDRAQ 1006
Query: 209 ADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEE 388
ADE + +L+A +++ +++L + + + S+ + +T + + +L ++
Sbjct: 1007 ADEVLQLREELEALRRQKGAREAEVLLLQQRVAALAEEKSRAQEKVTEK--EVVKLQNDP 1064
Query: 389 ARERATLLGKFRNLEHD---LDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYE--- 550
E +++ L+ D D +RE+ EEE D ++L K A A+ + E
Sbjct: 1065 QLE-----AEYQQLQEDHQRQDQLREKQEEELSFLQDKLKRLEKERAMAEGKITVKEVLK 1119
Query: 551 -SEGVARSEELEEAKRKLQ-----ARLAEAEET--------IESLNQKVVALEKTKQ--- 679
+ A E+ + R+ + AR ++ E+T +E N KVV EK ++
Sbjct: 1120 VEKDAATEREVSDLTRQYEDEAAKARASQREKTELLRKIWALEEENAKVVVQEKVREIVR 1179
Query: 680 ---RLATEVEDLQLEV 718
+ +EV +L+LE+
Sbjct: 1180 PDPKAESEVANLRLEL 1195
Score = 38.7 bits (86), Expect = 0.023
Identities = 43/194 (22%), Positives = 87/194 (44%)
Frame = +2
Query: 134 LSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQ 313
L N+K ++I + Q ++ ++ + + + + + D + +KL LL S
Sbjct: 767 LKNQKNLLDEIASREQ-EVQKICANSQQYQQAVKDYELEAEKLR----SLLDLENGRSSH 821
Query: 314 VSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADL 493
VS+ ++++ T E+ LA + A + +NLE L+ +R+Q E E + L
Sbjct: 822 VSKRARLQSPATKVKEEEAALAAKFTEVYAINRQRLQNLEFALNLLRQQPEVEVTHET-L 880
Query: 494 QRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKT 673
QR + E + W+ + E +E E +R+L+ + +E I +L +
Sbjct: 881 QRNRPDSGVE-EAWKIRKE------LDEETERRRQLENEVKSTQEEIWTLRNQGPQESVV 933
Query: 674 KQRLATEVEDLQLE 715
++ + +V D LE
Sbjct: 934 RKEVLKKVPDPVLE 947
Score = 38.7 bits (86), Expect = 0.023
Identities = 26/93 (27%), Positives = 46/93 (49%), Gaps = 8/93 (8%)
Frame = +2
Query: 449 IREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEEL--------EEAKRKLQ 604
IR++++EE E + L+ ++ E R++ E V R E L EE+ ++LQ
Sbjct: 895 IRKELDEETERRRQLENEVKSTQEEIWTLRNQGPQESVVRKEVLKKVPDPVLEESFQQLQ 954
Query: 605 ARLAEAEETIESLNQKVVALEKTKQRLATEVED 703
LAE + + L +++ AL+ + L E D
Sbjct: 955 RTLAEEQHKNQLLQEELEALQLQLRALEQETRD 987
Score = 31.5 bits (68), Expect = 3.5
Identities = 50/210 (23%), Positives = 92/210 (43%), Gaps = 6/210 (2%)
Frame = +2
Query: 113 LRAGLDHLSNEKAAQEK-IVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLR 289
L AGLD ++++ QEK I L+ L + ++ D A R + + + L IE + R
Sbjct: 507 LLAGLDKVASDLDRQEKAITGILRPPLEQGRAVQDSAERAKDLKNITNELLRIE-PEKTR 565
Query: 290 QLEEAESQVSQL--SKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQV 463
E E+ + L S L T++EDT R + LL + + + + +
Sbjct: 566 STAEGEAFIQALPGSGTTPLLRTRVEDTNR----KYEHLLQLLDLAQEKVDVANRLEKSL 621
Query: 464 EEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQAR---LAEAEETI 634
++ E A + L++ + + R +S+G +EL +LQA+ L E E+ +
Sbjct: 622 QQSWELLATHENHLNQDDTVPESSR-VLDSKG----QELAPMACELQAQKSLLGEVEQNL 676
Query: 635 ESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
++ Q L Q ++E + EV +
Sbjct: 677 QAAKQCSSTLASRFQEHCPDLERQEAEVHK 706
>AF001691-1|AAC17738.1| 1756|Homo sapiens 195 kDa cornified envelope
precursor protein.
Length = 1756
Score = 56.0 bits (129), Expect = 1e-07
Identities = 58/242 (23%), Positives = 110/242 (45%), Gaps = 15/242 (6%)
Frame = +2
Query: 44 DQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEAN 223
++L+++K + + + E LRA + + + + +L+ +L +Q + E
Sbjct: 1341 EELSRVKERVVQQEVVRYEEEPGLRAEASAFAESIDVELRQIDKLRAELRRLQRRRTELE 1400
Query: 224 RTLNDLDA---AKKKLSIENSDLLRQL-----EEAESQVSQLSKIKVSLTTQLEDTKRLA 379
R L +L+ A+++ E L ++L EEAE++ KV L + + A
Sbjct: 1401 RQLEELERERQARREAEREVQRLQQRLAALEQEEAEAREKVTHTQKVVLQQDPQQAREHA 1460
Query: 380 ------DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRS 541
+EE R L G+ L L + E+ E + + Q+ K + E ++ R
Sbjct: 1461 LLRLQLEEEQHRRQLLEGELETLRRKLAAL-EKAEVKEKVVLSESVQVEKGDTEQEIQRL 1519
Query: 542 KYESEGVARSE-ELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEV 718
K E +RS+ EL+ +L+ARL+E E ++++ L + +L E ++LQLE
Sbjct: 1520 KSSLEEESRSKRELDVEVSRLEARLSELEFHNSKSSKELDFLREENHKLQLERQNLQLET 1579
Query: 719 DR 724
R
Sbjct: 1580 RR 1581
Score = 38.7 bits (86), Expect = 0.023
Identities = 43/194 (22%), Positives = 87/194 (44%)
Frame = +2
Query: 134 LSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQ 313
L N+K ++I + Q ++ ++ + + + + + D + +KL LL S
Sbjct: 767 LKNQKNLLDEIASREQ-EVQKICANSQQYQQAVKDYELEAEKLR----SLLDLENGRSSH 821
Query: 314 VSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADL 493
VS+ ++++ T E+ LA + A + +NLE L+ +R+Q E E + L
Sbjct: 822 VSKRARLQSPATKVKEEEAALAAKFTEVYAINRQRLQNLEFALNLLRQQPEVEVTHET-L 880
Query: 494 QRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKT 673
QR + E + W+ + E +E E +R+L+ + +E I +L +
Sbjct: 881 QRNRPDSGVE-EAWKIRKE------LDEETERRRQLENEVKSTQEEIWTLRNQGPQESVV 933
Query: 674 KQRLATEVEDLQLE 715
++ + +V D LE
Sbjct: 934 RKEVLKKVPDPVLE 947
Score = 38.7 bits (86), Expect = 0.023
Identities = 26/93 (27%), Positives = 46/93 (49%), Gaps = 8/93 (8%)
Frame = +2
Query: 449 IREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEEL--------EEAKRKLQ 604
IR++++EE E + L+ ++ E R++ E V R E L EE+ ++LQ
Sbjct: 895 IRKELDEETERRRQLENEVKSTQEEIWTLRNQGPQESVVRKEVLKKVPDPVLEESFQQLQ 954
Query: 605 ARLAEAEETIESLNQKVVALEKTKQRLATEVED 703
LAE + + L +++ AL+ + L E D
Sbjct: 955 RTLAEEQHKNQLLQEELEALQLQLRALEQETRD 987
Score = 37.1 bits (82), Expect = 0.071
Identities = 55/256 (21%), Positives = 114/256 (44%), Gaps = 28/256 (10%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEK--AAQEKIVKQLQHQLNEVQSK 208
E QL + A+ + E+ L+ L L E QE + K++ ++ +++
Sbjct: 948 ESFQQLQRTLAEEQHKNQLLQEELEALQLQLRALEQETRDGGQEYVFKEVL-RIEPDRAQ 1006
Query: 209 ADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEE 388
ADE + +L+A +++ +++L + + + S+ + +T + + +L ++
Sbjct: 1007 ADEVLQLREELEALRRQKGAREAEVLLLQQRVAALAEEKSRAQEKVTEK--EVVKLQNDP 1064
Query: 389 ARERATLLGKFRNLEHD---LDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYE--- 550
E +++ L+ D D +RE+ EEE D ++L K A A+ + E
Sbjct: 1065 QLE-----AEYQQLQEDHQRQDQLREKQEEELSFLQDKLKRLEKERAMAEGKITVKEVLK 1119
Query: 551 -SEGVARSEELEEAKRKLQ-----ARLAEAEET--------IESLNQKVVALEKTKQ--- 679
+ A E+ + R+ + AR ++ E+T +E N KVV EK ++
Sbjct: 1120 VEKDAATEREVSDLTRQYEDEAAKARASQREKTELLRKIWALEEENAKVVVQEKVREIVR 1179
Query: 680 ---RLATEVEDLQLEV 718
+ +EV +L+LE+
Sbjct: 1180 PDPKAESEVANLRLEL 1195
Score = 33.1 bits (72), Expect = 1.2
Identities = 51/210 (24%), Positives = 92/210 (43%), Gaps = 6/210 (2%)
Frame = +2
Query: 113 LRAGLDHLSNEKAAQEK-IVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLR 289
L AGLD ++++ QEK I L+ L + ++ D A R + + + L IE + R
Sbjct: 507 LLAGLDKVASDLDRQEKAITGILRPPLEQGRAVQDSAERAKDLKNITNELLRIE-PEKTR 565
Query: 290 QLEEAESQVSQL--SKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQV 463
E E+ + L S L TQ+EDT R + LL + + + + +
Sbjct: 566 STAEGEAFIQALPGSGTTPLLRTQVEDTNR----KYEHLLQLLDLAQEKVDVANRLEKSL 621
Query: 464 EEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQAR---LAEAEETI 634
++ E A + L++ + + R +S+G +EL +LQA+ L E E+ +
Sbjct: 622 QQSWELLATHENHLNQDDTVPESSR-VLDSKG----QELAAMACELQAQKSLLGEVEQNL 676
Query: 635 ESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
++ Q L Q ++E + EV +
Sbjct: 677 QAAKQCSSTLASRFQEHCPDLERQEAEVHK 706
>AB208858-1|BAD92095.1| 400|Homo sapiens golgin 97 variant protein.
Length = 400
Score = 56.0 bits (129), Expect = 1e-07
Identities = 49/213 (23%), Positives = 97/213 (45%), Gaps = 4/213 (1%)
Frame = +2
Query: 5 SAGRFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQH 184
++ + SD+ ++L++L + + E+ R + + + L ++ + +++QL
Sbjct: 117 NSNQMSSDLSQKLEELQRHYSTLEEQRDHVIASKTGAESKITALEQKEQELQALIQQLSI 176
Query: 185 QLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLED 364
L +V ++ E + L +K S+E L Q E V +L K K LED
Sbjct: 177 DLQKVTAETQEKEDVITHLQ--EKVASLEKR--LEQNLSGEEHVQELLKEKTLAEQNLED 232
Query: 365 TKR--LADEEARERA--TLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQL 532
T++ LA ++ +A TL + R LE L EQ+ ++++G Q + A A
Sbjct: 233 TRQQLLAARSSQAKAINTLETRVRELEQTLQASEEQL-QQSKGIVAAQETQIQELAAANQ 291
Query: 533 WRSKYESEGVARSEELEEAKRKLQARLAEAEET 631
S + + +A ++ E + L+A++ E T
Sbjct: 292 ESSHVQQQALALEQQFLERTQALEAQIVALERT 324
Score = 41.1 bits (92), Expect = 0.004
Identities = 46/234 (19%), Positives = 103/234 (44%), Gaps = 16/234 (6%)
Frame = +2
Query: 26 DMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQS 205
+ E++DQL K K + ++ +L D + + Q++ + +++H L + +
Sbjct: 33 EWSEKMDQLEKEKNILTAQLQEMKNQSMNLFQRRDEMDELEGFQQQELSKIKHMLLKKEE 92
Query: 206 KADEANRTLN----DLDAAKKKLSIEN---SDLLRQLEEAESQVSQLSKIK---VSLTTQ 355
+ + L +L +++L N SDL ++LEE + S L + + ++ T
Sbjct: 93 SLGKMEQELEARTRELSRTQEELMNSNQMSSDLSQKLEELQRHYSTLEEQRDHVIASKTG 152
Query: 356 LEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLS------KAN 517
E +++ +E L+ + L DL + + +E+ + LQ +++ + N
Sbjct: 153 AESKITALEQKEQELQALI---QQLSIDLQKVTAETQEKEDVITHLQEKVASLEKRLEQN 209
Query: 518 AEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQ 679
+ + E + LE+ +++L A + + I +L +V LE+T Q
Sbjct: 210 LSGEEHVQELLKEKTLAEQNLEDTRQQLLAARSSQAKAINTLETRVRELEQTLQ 263
Score = 40.3 bits (90), Expect = 0.008
Identities = 42/160 (26%), Positives = 77/160 (48%), Gaps = 12/160 (7%)
Frame = +2
Query: 281 LLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADE--EARERATLLGKFRNLEHDLDNIR 454
L R+ +E ++ QL K K LT QL++ K + + R+ L F+ + +L I+
Sbjct: 27 LARKDQEWSEKMDQLEKEKNILTAQLQEMKNQSMNLFQRRDEMDELEGFQ--QQELSKIK 84
Query: 455 EQV--EEEAEGKADLQ-----RQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARL 613
+ +EE+ GK + + R+LS+ E L S S + S++LEE +R
Sbjct: 85 HMLLKKEESLGKMEQELEARTRELSRTQEE--LMNSNQMSSDL--SQKLEELQRHYSTLE 140
Query: 614 AEAEETIES---LNQKVVALEKTKQRLATEVEDLQLEVDR 724
+ + I S K+ ALE+ +Q L ++ L +++ +
Sbjct: 141 EQRDHVIASKTGAESKITALEQKEQELQALIQQLSIDLQK 180
>AB002387-1|BAA20843.2| 1296|Homo sapiens KIAA0389 protein.
Length = 1296
Score = 56.0 bits (129), Expect = 1e-07
Identities = 44/180 (24%), Positives = 85/180 (47%), Gaps = 1/180 (0%)
Frame = +2
Query: 134 LSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQ 313
L + K K +K L+ ++ + +K T + L + +LL L++ + Q
Sbjct: 871 LKDGKPEMNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYDALVKSSEELLSALQKKKQQ 930
Query: 314 VSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADL 493
+ +++ ++ KR ++E R R + R ++ +++ R+Q EEE + + D
Sbjct: 931 EEEAERLRRIQEEMEKERKRREEDEKRRRKE--EEERRMKLEMEAKRKQEEEERKKREDD 988
Query: 494 QRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAE-ETIESLNQKVVALEK 670
++++ +A EAQL R K E E E R+L R+A++E E I Q +AL +
Sbjct: 989 EKRI-QAEVEAQLARQKEEESQQQAVLEQERRDRELALRIAQSEAELISDEAQADLALRR 1047
>AY681966-1|AAV87216.1| 2069|Homo sapiens citron protein.
Length = 2069
Score = 55.2 bits (127), Expect = 3e-07
Identities = 49/177 (27%), Positives = 87/177 (49%), Gaps = 9/177 (5%)
Frame = +2
Query: 140 NEKAAQEK--IVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQ 313
+E+ A EK I+ + + +N + SK + + +L A K + + R ++ E
Sbjct: 791 HEEEAHEKGKILSEQKAMINAMDSKIRSLEQRIVELSEANKLAANSSLFTQRNMKAQEEM 850
Query: 314 VSQLSKIKVSLTTQ---LEDTKRLADEEARERATLLGKFRNLEHDLDN-IREQVEEEAEG 481
+S+L + K L TQ LE R +E+ + + +N +L+ +RE E E
Sbjct: 851 ISELRQQKFYLETQAGKLEAQNRKLEEQLEKISHQDHSDKNRLLELETRLREVSLEHEEQ 910
Query: 482 KADLQRQLSKANAEAQLWRSKYESEGVARS---EELEEAKRKLQARLAEAEETIESL 643
K +L+RQL++ Q S+ + AR+ +L +AK +L+ AEAEE I++L
Sbjct: 911 KLELKRQLTELQLSLQERESQLTALQAARAALESQLRQAKTELEETTAEAEEEIQAL 967
Score = 47.2 bits (107), Expect = 7e-05
Identities = 50/228 (21%), Positives = 98/228 (42%)
Frame = +2
Query: 26 DMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQS 205
D+ + + + LK E+ R + S+ +D L H E++ + + +K+ ++Q +V+
Sbjct: 506 DLATYITECSSLKRSLEQARMEV-SQEDDKALQLLHDIREQSRKLQEIKEQEYQA-QVEE 563
Query: 206 KADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADE 385
N+ DL +A+++ + S+L E+ + + +L K
Sbjct: 564 MRLMMNQLEEDLVSARRRSDLYESEL----RESRLAAEEFKRKATECQHKLLKAKDQGKP 619
Query: 386 EARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVA 565
E E A L + + ++E++E+ + + L + R++ E E +
Sbjct: 620 EVGEYAKLEKINAEQQLKIQELQEKLEKAVKASTEATELLQNIRQAKE--RAERELEKLQ 677
Query: 566 RSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQ 709
E+ E RK +L EAEE SL KV LE ++R +D+Q
Sbjct: 678 NREDSSEGIRK---KLVEAEERRHSLENKVKRLETMERRENRLKDDIQ 722
Score = 41.1 bits (92), Expect = 0.004
Identities = 60/246 (24%), Positives = 101/246 (41%), Gaps = 12/246 (4%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFS-----------EVNDLRAGLDHLSNEKAAQEKI 166
++D+ EQL+QL + A+ Y S E+ LR+ +DHL E
Sbjct: 988 ITDLEEQLNQLTEDNAELNNQNF-YLSKQLDEASGANDEIVQLRSEVDHLRRE------- 1039
Query: 167 VKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSL 346
+ + + QL + + T L+ L N +LL + + E+ S L K
Sbjct: 1040 ITEREMQLTSQKQTMEALKTTCTMLEEQVMDLEALNDELLEKERQWEAWRSVLGDEKSQF 1099
Query: 347 TTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVE-EEAEGKADLQRQLSKANAE 523
++ + +R+ D E + RA + + R+ VE E KA++ L +A E
Sbjct: 1100 ECRVRELQRMLDTEKQSRA-------RADQRITESRQVVELAVKEHKAEI-LALQQALKE 1151
Query: 524 AQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVED 703
+L ++E L + L+ + A E SL QK+ + KQRL E
Sbjct: 1152 QKL-----------KAESLSDKLNDLEKKHAMLEMNARSLQQKLETERELKQRLLEEQAK 1200
Query: 704 LQLEVD 721
LQ ++D
Sbjct: 1201 LQQQMD 1206
Score = 36.3 bits (80), Expect = 0.12
Identities = 57/248 (22%), Positives = 102/248 (41%), Gaps = 13/248 (5%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQL------Q 181
+ ++ E+L++ K +A + L+ L N + + E I K+L +
Sbjct: 638 IQELQEKLEKAVKASTEATELLQNIRQAKERAERELEKLQNREDSSEGIRKKLVEAEERR 697
Query: 182 HQLNEVQSKADEANRTLNDL--DAAKKKLSIEN-SDLLRQLEEAESQVSQLSKIKVSLTT 352
H L + + R N L D K I+ +D + +LEE + +Q+S L
Sbjct: 698 HSLENKVKRLETMERRENRLKDDIQTKSQQIQQMADKILELEEKHRE-AQVSA--QHLEV 754
Query: 353 QLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKAD-LQRQLSKANAEAQ 529
L+ ++ +E+ + + K + L+N+ ++ EEEA K L Q + NA
Sbjct: 755 HLKQKEQHYEEKIKVLDNQIKKDLADKETLENMMQRHEEEAHEKGKILSEQKAMINAMDS 814
Query: 530 LWRSKYESEGVARSEELEEAKRK---LQARLAEAEETIESLNQKVVALEKTKQRLATEVE 700
RS E V SE + A Q + EE I L Q+ LE +L +
Sbjct: 815 KIRS-LEQRIVELSEANKLAANSSLFTQRNMKAQEEMISELRQQKFYLETQAGKLEAQNR 873
Query: 701 DLQLEVDR 724
L+ ++++
Sbjct: 874 KLEEQLEK 881
>AY257469-1|AAP13528.1| 2027|Homo sapiens rho/rac-interacting citron
kinase protein.
Length = 2027
Score = 55.2 bits (127), Expect = 3e-07
Identities = 49/177 (27%), Positives = 87/177 (49%), Gaps = 9/177 (5%)
Frame = +2
Query: 140 NEKAAQEK--IVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQ 313
+E+ A EK I+ + + +N + SK + + +L A K + + R ++ E
Sbjct: 749 HEEEAHEKGKILSEQKAMINAMDSKIRSLEQRIVELSEANKLAANSSLFTQRNMKAQEEM 808
Query: 314 VSQLSKIKVSLTTQ---LEDTKRLADEEARERATLLGKFRNLEHDLDN-IREQVEEEAEG 481
+S+L + K L TQ LE R +E+ + + +N +L+ +RE E E
Sbjct: 809 ISELRQQKFYLETQAGKLEAQNRKLEEQLEKISHQDHSDKNRLLELETRLREVSLEHEEQ 868
Query: 482 KADLQRQLSKANAEAQLWRSKYESEGVARS---EELEEAKRKLQARLAEAEETIESL 643
K +L+RQL++ Q S+ + AR+ +L +AK +L+ AEAEE I++L
Sbjct: 869 KLELKRQLTELQLSLQERESQLTALQAARAALESQLRQAKTELEETTAEAEEEIQAL 925
Score = 41.1 bits (92), Expect = 0.004
Identities = 60/246 (24%), Positives = 101/246 (41%), Gaps = 12/246 (4%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFS-----------EVNDLRAGLDHLSNEKAAQEKI 166
++D+ EQL+QL + A+ Y S E+ LR+ +DHL E
Sbjct: 946 ITDLEEQLNQLTEDNAELNNQNF-YLSKQLDEASGANDEIVQLRSEVDHLRRE------- 997
Query: 167 VKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSL 346
+ + + QL + + T L+ L N +LL + + E+ S L K
Sbjct: 998 ITEREMQLTSQKQTMEALKTTCTMLEEQVMDLEALNDELLEKERQWEAWRSVLGDEKSQF 1057
Query: 347 TTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVE-EEAEGKADLQRQLSKANAE 523
++ + +R+ D E + RA + + R+ VE E KA++ L +A E
Sbjct: 1058 ECRVRELQRMLDTEKQSRA-------RADQRITESRQVVELAVKEHKAEI-LALQQALKE 1109
Query: 524 AQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVED 703
+L ++E L + L+ + A E SL QK+ + KQRL E
Sbjct: 1110 QKL-----------KAESLSDKLNDLEKKHAMLEMNARSLQQKLETERELKQRLLEEQAK 1158
Query: 704 LQLEVD 721
LQ ++D
Sbjct: 1159 LQQQMD 1164
>AC002563-2|AAB71327.1| 1286|Homo sapiens WUGSC:H_127H14.1 protein.
Length = 1286
Score = 55.2 bits (127), Expect = 3e-07
Identities = 49/177 (27%), Positives = 87/177 (49%), Gaps = 9/177 (5%)
Frame = +2
Query: 140 NEKAAQEK--IVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQ 313
+E+ A EK I+ + + +N + SK + + +L A K + + R ++ E
Sbjct: 23 HEEEAHEKGKILSEQKAMINAMDSKIRSLEQRIVELSEANKLAANSSLFTQRNMKAQEEM 82
Query: 314 VSQLSKIKVSLTTQ---LEDTKRLADEEARERATLLGKFRNLEHDLDN-IREQVEEEAEG 481
+S+L + K L TQ LE R +E+ + + +N +L+ +RE E E
Sbjct: 83 ISELRQQKFYLETQAGKLEAQNRKLEEQLEKISHQDHSDKNRLLELETRLREVSLEHEEQ 142
Query: 482 KADLQRQLSKANAEAQLWRSKYESEGVARS---EELEEAKRKLQARLAEAEETIESL 643
K +L+RQL++ Q S+ + AR+ +L +AK +L+ AEAEE I++L
Sbjct: 143 KLELKRQLTELQLSLQERESQLTALQAARAALESQLRQAKTELEETTAEAEEEIQAL 199
Score = 41.1 bits (92), Expect = 0.004
Identities = 60/246 (24%), Positives = 101/246 (41%), Gaps = 12/246 (4%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFS-----------EVNDLRAGLDHLSNEKAAQEKI 166
++D+ EQL+QL + A+ Y S E+ LR+ +DHL E
Sbjct: 220 ITDLEEQLNQLTEDNAELNNQNF-YLSKQLDEASGANDEIVQLRSEVDHLRRE------- 271
Query: 167 VKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSL 346
+ + + QL + + T L+ L N +LL + + E+ S L K
Sbjct: 272 ITEREMQLTSQKQTMEALKTTCTMLEEQVMDLEALNDELLEKERQWEAWRSVLGDEKSQF 331
Query: 347 TTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVE-EEAEGKADLQRQLSKANAE 523
++ + +R+ D E + RA + + R+ VE E KA++ L +A E
Sbjct: 332 ECRVRELQRMLDTEKQSRA-------RADQRITESRQVVELAVKEHKAEI-LALQQALKE 383
Query: 524 AQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVED 703
+L ++E L + L+ + A E SL QK+ + KQRL E
Sbjct: 384 QKL-----------KAESLSDKLNDLEKKHAMLEMNARSLQQKLETERELKQRLLEEQAK 432
Query: 704 LQLEVD 721
LQ ++D
Sbjct: 433 LQQQMD 438
>AB023166-1|BAA76793.2| 1559|Homo sapiens KIAA0949 protein protein.
Length = 1559
Score = 55.2 bits (127), Expect = 3e-07
Identities = 49/177 (27%), Positives = 87/177 (49%), Gaps = 9/177 (5%)
Frame = +2
Query: 140 NEKAAQEK--IVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQ 313
+E+ A EK I+ + + +N + SK + + +L A K + + R ++ E
Sbjct: 297 HEEEAHEKGKILSEQKAMINAMDSKIRSLEQRIVELSEANKLAANSSLFTQRNMKAQEEM 356
Query: 314 VSQLSKIKVSLTTQ---LEDTKRLADEEARERATLLGKFRNLEHDLDN-IREQVEEEAEG 481
+S+L + K L TQ LE R +E+ + + +N +L+ +RE E E
Sbjct: 357 ISELRQQKFYLETQAGKLEAQNRKLEEQLEKISHQDHSDKNRLLELETRLREVSLEHEEQ 416
Query: 482 KADLQRQLSKANAEAQLWRSKYESEGVARS---EELEEAKRKLQARLAEAEETIESL 643
K +L+RQL++ Q S+ + AR+ +L +AK +L+ AEAEE I++L
Sbjct: 417 KLELKRQLTELQLSLQERESQLTALQAARAALESQLRQAKTELEETTAEAEEEIQAL 473
Score = 41.1 bits (92), Expect = 0.004
Identities = 60/246 (24%), Positives = 101/246 (41%), Gaps = 12/246 (4%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFS-----------EVNDLRAGLDHLSNEKAAQEKI 166
++D+ EQL+QL + A+ Y S E+ LR+ +DHL E
Sbjct: 494 ITDLEEQLNQLTEDNAELNNQNF-YLSKQLDEASGANDEIVQLRSEVDHLRRE------- 545
Query: 167 VKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSL 346
+ + + QL + + T L+ L N +LL + + E+ S L K
Sbjct: 546 ITEREMQLTSQKQTMEALKTTCTMLEEQVMDLEALNDELLEKERQWEAWRSVLGDEKSQF 605
Query: 347 TTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVE-EEAEGKADLQRQLSKANAE 523
++ + +R+ D E + RA + + R+ VE E KA++ L +A E
Sbjct: 606 ECRVRELQRMLDTEKQSRA-------RADQRITESRQVVELAVKEHKAEI-LALQQALKE 657
Query: 524 AQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVED 703
+L ++E L + L+ + A E SL QK+ + KQRL E
Sbjct: 658 QKL-----------KAESLSDKLNDLEKKHAMLEMNARSLQQKLETERELKQRLLEEQAK 706
Query: 704 LQLEVD 721
LQ ++D
Sbjct: 707 LQQQMD 712
>Z54367-1|CAA91196.1| 4684|Homo sapiens plectin protein.
Length = 4684
Score = 54.8 bits (126), Expect = 3e-07
Identities = 57/245 (23%), Positives = 107/245 (43%), Gaps = 15/245 (6%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV-QSKA 211
E L Q L K K + Q E L+A + L +K ++ ++LQ ++ Q A
Sbjct: 2436 EDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLA 2495
Query: 212 DEAN---RTLN-------DLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLE 361
+E RTL ++ A ++L + +++ R AE + K + +L
Sbjct: 2496 EETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLH 2555
Query: 362 DTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRS 541
T+ E+ TL + + +HD + +RE + A+L+R+ K EA+L +
Sbjct: 2556 RTELATQEKVTLVQTLEIQRQQSDHDAERLREAI-------AELEREKEKLQQEAKLLQL 2608
Query: 542 KYESEGVARSEE-LEEAKRKLQARLAEAEETIES---LNQKVVALEKTKQRLATEVEDLQ 709
K E + E+ L+E + Q+ L+E + ++ + Q+ LE+ Q + + L+
Sbjct: 2609 KSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLR 2668
Query: 710 LEVDR 724
E R
Sbjct: 2669 EEQQR 2673
Score = 44.8 bits (101), Expect = 4e-04
Identities = 47/196 (23%), Positives = 92/196 (46%), Gaps = 3/196 (1%)
Frame = +2
Query: 143 EKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAE-SQVS 319
E AQ+++ + + +++ E R L + + A+ + + RQ EAE ++V
Sbjct: 1839 EGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVR 1898
Query: 320 QLSKIKVSLTTQLEDTKRLADEEARERATL-LGKFRNLEHDLDNIREQVEEEAEGKADLQ 496
++ ++ + E+ R E++++R G+FR L + +R EE A Q
Sbjct: 1899 AEMEVLLASKAKAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEE-----AKRQ 1953
Query: 497 RQLSKANAEAQLWRSKYESEGVARSEELEEAKR-KLQARLAEAEETIESLNQKVVALEKT 673
RQL++ +A Q R++ E + + EA R K +A +A E+ E+ + +A ++
Sbjct: 1954 RQLAEEDAARQ--RAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEA 2011
Query: 674 KQRLATEVEDLQLEVD 721
QR E + Q + D
Sbjct: 2012 FQRRRLEEQAAQHKAD 2027
Score = 43.2 bits (97), Expect = 0.001
Identities = 54/226 (23%), Positives = 101/226 (44%), Gaps = 15/226 (6%)
Frame = +2
Query: 62 KAKAEKXRAQYFSEVND---LRAGLDHLSNEKAAQEKIVKQLQH----QLNEVQSKADEA 220
+A+AE+ A+ + + + L+ + EK A+ + +++L Q ++ +A +
Sbjct: 1965 RAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQH 2024
Query: 221 NRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARER 400
+ + A +K S +S+L RQ E + Q +++ + ++ A +A E
Sbjct: 2025 KADIEERLAQLRKAS--DSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKA-EL 2081
Query: 401 ATLLGKFRNLEHDLDNIREQVEEEAEGKADL--QRQLSKANAEAQLWRSKYESEGVARS- 571
LG+ R+ D +EQ E EA + L + + + AE ++ +S E AR
Sbjct: 2082 ELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQR 2141
Query: 572 ----EELEEAKRKL-QARLAEAEETIESLNQKVVALEKTKQRLATE 694
EE+E K K+ +AR ES Q +A E ++RL E
Sbjct: 2142 KAALEEVERLKAKVEEARSLRERAEQESARQLQLAQEAAQKRLQAE 2187
Score = 42.3 bits (95), Expect = 0.002
Identities = 38/181 (20%), Positives = 82/181 (45%), Gaps = 6/181 (3%)
Frame = +2
Query: 194 EVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKR 373
E+QSK L+ + ++ + + L + E Q ++ + + QLE +
Sbjct: 1714 ELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERQLERWQL 1773
Query: 374 LADEEARERAT---LLGKFRNLEHDLDNIREQVEEEAE--GKADLQRQLSKANAEAQLWR 538
A+E R R +L + + + + +E+ E EA GKA+ Q + AE +L +
Sbjct: 1774 KANEALRLRLQAEEVLQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEK 1833
Query: 539 SKYESEGVARSE-ELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLE 715
+ +EG A+ E+ +L+A + E+ + L +++ L++ + ++L+ E
Sbjct: 1834 QRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAE 1893
Query: 716 V 718
+
Sbjct: 1894 L 1894
Score = 41.9 bits (94), Expect = 0.003
Identities = 60/245 (24%), Positives = 105/245 (42%), Gaps = 9/245 (3%)
Frame = +2
Query: 14 RFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLN 193
+++ + E L ++ + + AE+ RA+ + ++ A L+ A + Q + +
Sbjct: 1469 QYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAK 1528
Query: 194 EVQSKADE--ANRTLNDLDAAKKKLSI-ENSDLLRQLEEAESQVSQLSKIKVSLTTQLED 364
E+Q + E R +DA ++K SI E LRQ EAE Q
Sbjct: 1529 ELQQRIQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQA---------------- 1572
Query: 365 TKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSK 544
+ EA ER+ L +E ++ +R Q+E +RQ A E Q R++
Sbjct: 1573 --KARQAEAAERSRL-----RIEEEIRVVRLQLEAT-------ERQRGGAEGELQALRAR 1618
Query: 545 -YESEGVAR--SEELEEAKRKLQ---ARLAEAEETIESLNQKVVALEKTKQRLATEVEDL 706
E+E R EE E +R++Q R +AE + S + + KQR +E+L
Sbjct: 1619 AEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEEL 1678
Query: 707 QLEVD 721
+L+ +
Sbjct: 1679 RLQAE 1683
>U63610-1|AAB05428.1| 4574|Homo sapiens plectin protein.
Length = 4574
Score = 54.8 bits (126), Expect = 3e-07
Identities = 57/245 (23%), Positives = 107/245 (43%), Gaps = 15/245 (6%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV-QSKA 211
E L Q L K K + Q E L+A + L +K ++ ++LQ ++ Q A
Sbjct: 2326 EDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLA 2385
Query: 212 DEAN---RTLN-------DLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLE 361
+E RTL ++ A ++L + +++ R AE + K + +L
Sbjct: 2386 EETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLH 2445
Query: 362 DTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRS 541
T+ E+ TL + + +HD + +RE + A+L+R+ K EA+L +
Sbjct: 2446 RTELATQEKVTLVQTLEIQRQQSDHDAERLREAI-------AELEREKEKLQQEAKLLQL 2498
Query: 542 KYESEGVARSEE-LEEAKRKLQARLAEAEETIES---LNQKVVALEKTKQRLATEVEDLQ 709
K E + E+ L+E + Q+ L+E + ++ + Q+ LE+ Q + + L+
Sbjct: 2499 KSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLR 2558
Query: 710 LEVDR 724
E R
Sbjct: 2559 EEQQR 2563
Score = 44.8 bits (101), Expect = 4e-04
Identities = 47/196 (23%), Positives = 92/196 (46%), Gaps = 3/196 (1%)
Frame = +2
Query: 143 EKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAE-SQVS 319
E AQ+++ + + +++ E R L + + A+ + + RQ EAE ++V
Sbjct: 1729 EGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVR 1788
Query: 320 QLSKIKVSLTTQLEDTKRLADEEARERATL-LGKFRNLEHDLDNIREQVEEEAEGKADLQ 496
++ ++ + E+ R E++++R G+FR L + +R EE A Q
Sbjct: 1789 AEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEE-----AKRQ 1843
Query: 497 RQLSKANAEAQLWRSKYESEGVARSEELEEAKR-KLQARLAEAEETIESLNQKVVALEKT 673
RQL++ +A Q R++ E + + EA R K +A +A E+ E+ + +A ++
Sbjct: 1844 RQLAEEDAARQ--RAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEA 1901
Query: 674 KQRLATEVEDLQLEVD 721
QR E + Q + D
Sbjct: 1902 FQRRRLEEQAAQHKAD 1917
Score = 42.3 bits (95), Expect = 0.002
Identities = 38/181 (20%), Positives = 85/181 (46%), Gaps = 6/181 (3%)
Frame = +2
Query: 194 EVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKR 373
E+QSK L+ + ++ + + L + E Q ++ + + +LE +
Sbjct: 1604 ELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQL 1663
Query: 374 LADEEARER--ATLLGKFRNL-EHDLDNIREQVEEEAE--GKADLQRQLSKANAEAQLWR 538
A+E R R A + + ++L + + + +E+ E EA GKA+ Q + AE +L +
Sbjct: 1664 KANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEK 1723
Query: 539 SKYESEGVARSE-ELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLE 715
+ +EG A+ E+ +L+A + E+ + L +++ L++ + ++L+ E
Sbjct: 1724 QRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAE 1783
Query: 716 V 718
+
Sbjct: 1784 L 1784
Score = 41.9 bits (94), Expect = 0.003
Identities = 60/245 (24%), Positives = 105/245 (42%), Gaps = 9/245 (3%)
Frame = +2
Query: 14 RFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLN 193
+++ + E L ++ + + AE+ RA+ + ++ A L+ A + Q + +
Sbjct: 1359 QYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAK 1418
Query: 194 EVQSKADE--ANRTLNDLDAAKKKLSI-ENSDLLRQLEEAESQVSQLSKIKVSLTTQLED 364
E+Q + E R +DA ++K SI E LRQ EAE Q
Sbjct: 1419 ELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQA---------------- 1462
Query: 365 TKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSK 544
+ EA ER+ L +E ++ +R Q+E +RQ A E Q R++
Sbjct: 1463 --KARQAEAAERSRL-----RIEEEIRVVRLQLEAT-------ERQRGGAEGELQALRAR 1508
Query: 545 -YESEGVAR--SEELEEAKRKLQ---ARLAEAEETIESLNQKVVALEKTKQRLATEVEDL 706
E+E R EE E +R++Q R +AE + S + + KQR +E+L
Sbjct: 1509 AEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAETEAAREKQRALQALEEL 1568
Query: 707 QLEVD 721
+L+ +
Sbjct: 1569 RLQAE 1573
Score = 41.5 bits (93), Expect = 0.003
Identities = 55/227 (24%), Positives = 102/227 (44%), Gaps = 16/227 (7%)
Frame = +2
Query: 62 KAKAEKXRAQYFSEVND---LRAGLDHLSNEKAAQEKIVKQLQH----QLNEVQSKADEA 220
+A+AE+ A+ + + + L+ + EK A+ + +++L Q ++ +A +
Sbjct: 1855 RAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQH 1914
Query: 221 NRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARER 400
+ + A +K S +S+L RQ E + Q +++ + ++ A +A E
Sbjct: 1915 KADIEERLAQLRKAS--DSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKA-EL 1971
Query: 401 ATLLGKFRNLEHDLDNIREQVEEEAEGKADL--QRQLSKANAEAQLWRSKYESEGVARS- 571
LG+ R+ D +EQ E EA + L + + + AE ++ +S E AR
Sbjct: 1972 ELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQR 2031
Query: 572 ----EELEEAKRKLQ--ARLAEAEETIESLNQKVVALEKTKQRLATE 694
EE+E K ++ RL E E ES Q +A E ++RL E
Sbjct: 2032 KAALEEVERLKANVEEARRLRERAEQ-ESARQLQLAQEAAQKRLQAE 2077
>U53204-1|AAB05427.1| 4574|Homo sapiens plectin protein.
Length = 4574
Score = 54.8 bits (126), Expect = 3e-07
Identities = 57/245 (23%), Positives = 107/245 (43%), Gaps = 15/245 (6%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV-QSKA 211
E L Q L K K + Q E L+A + L +K ++ ++LQ ++ Q A
Sbjct: 2326 EDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLA 2385
Query: 212 DEAN---RTLN-------DLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLE 361
+E RTL ++ A ++L + +++ R AE + K + +L
Sbjct: 2386 EETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLH 2445
Query: 362 DTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRS 541
T+ E+ TL + + +HD + +RE + A+L+R+ K EA+L +
Sbjct: 2446 RTELATQEKVTLVQTLEIQRQQSDHDAERLREAI-------AELEREKEKLQQEAKLLQL 2498
Query: 542 KYESEGVARSEE-LEEAKRKLQARLAEAEETIES---LNQKVVALEKTKQRLATEVEDLQ 709
K E + E+ L+E + Q+ L+E + ++ + Q+ LE+ Q + + L+
Sbjct: 2499 KSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLR 2558
Query: 710 LEVDR 724
E R
Sbjct: 2559 EEQQR 2563
Score = 44.8 bits (101), Expect = 4e-04
Identities = 47/196 (23%), Positives = 92/196 (46%), Gaps = 3/196 (1%)
Frame = +2
Query: 143 EKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAE-SQVS 319
E AQ+++ + + +++ E R L + + A+ + + RQ EAE ++V
Sbjct: 1729 EGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVR 1788
Query: 320 QLSKIKVSLTTQLEDTKRLADEEARERATL-LGKFRNLEHDLDNIREQVEEEAEGKADLQ 496
++ ++ + E+ R E++++R G+FR L + +R EE A Q
Sbjct: 1789 AEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEE-----AKRQ 1843
Query: 497 RQLSKANAEAQLWRSKYESEGVARSEELEEAKR-KLQARLAEAEETIESLNQKVVALEKT 673
RQL++ +A Q R++ E + + EA R K +A +A E+ E+ + +A ++
Sbjct: 1844 RQLAEEDAARQ--RAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEA 1901
Query: 674 KQRLATEVEDLQLEVD 721
QR E + Q + D
Sbjct: 1902 FQRRRLEEQAAQHKAD 1917
Score = 42.3 bits (95), Expect = 0.002
Identities = 38/181 (20%), Positives = 85/181 (46%), Gaps = 6/181 (3%)
Frame = +2
Query: 194 EVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKR 373
E+QSK L+ + ++ + + L + E Q ++ + + +LE +
Sbjct: 1604 ELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQL 1663
Query: 374 LADEEARER--ATLLGKFRNL-EHDLDNIREQVEEEAE--GKADLQRQLSKANAEAQLWR 538
A+E R R A + + ++L + + + +E+ E EA GKA+ Q + AE +L +
Sbjct: 1664 KANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEK 1723
Query: 539 SKYESEGVARSE-ELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLE 715
+ +EG A+ E+ +L+A + E+ + L +++ L++ + ++L+ E
Sbjct: 1724 QRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAE 1783
Query: 716 V 718
+
Sbjct: 1784 L 1784
Score = 41.9 bits (94), Expect = 0.003
Identities = 60/245 (24%), Positives = 105/245 (42%), Gaps = 9/245 (3%)
Frame = +2
Query: 14 RFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLN 193
+++ + E L ++ + + AE+ RA+ + ++ A L+ A + Q + +
Sbjct: 1359 QYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAK 1418
Query: 194 EVQSKADE--ANRTLNDLDAAKKKLSI-ENSDLLRQLEEAESQVSQLSKIKVSLTTQLED 364
E+Q + E R +DA ++K SI E LRQ EAE Q
Sbjct: 1419 ELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQA---------------- 1462
Query: 365 TKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSK 544
+ EA ER+ L +E ++ +R Q+E +RQ A E Q R++
Sbjct: 1463 --KARQAEAAERSRL-----RIEEEIRVVRLQLEAT-------ERQRGGAEGELQALRAR 1508
Query: 545 -YESEGVAR--SEELEEAKRKLQ---ARLAEAEETIESLNQKVVALEKTKQRLATEVEDL 706
E+E R EE E +R++Q R +AE + S + + KQR +E+L
Sbjct: 1509 AEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAETEAAREKQRALQALEEL 1568
Query: 707 QLEVD 721
+L+ +
Sbjct: 1569 RLQAE 1573
Score = 41.5 bits (93), Expect = 0.003
Identities = 55/227 (24%), Positives = 102/227 (44%), Gaps = 16/227 (7%)
Frame = +2
Query: 62 KAKAEKXRAQYFSEVND---LRAGLDHLSNEKAAQEKIVKQLQH----QLNEVQSKADEA 220
+A+AE+ A+ + + + L+ + EK A+ + +++L Q ++ +A +
Sbjct: 1855 RAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQH 1914
Query: 221 NRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARER 400
+ + A +K S +S+L RQ E + Q +++ + ++ A +A E
Sbjct: 1915 KADIEERLAQLRKAS--DSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKA-EL 1971
Query: 401 ATLLGKFRNLEHDLDNIREQVEEEAEGKADL--QRQLSKANAEAQLWRSKYESEGVARS- 571
LG+ R+ D +EQ E EA + L + + + AE ++ +S E AR
Sbjct: 1972 ELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQR 2031
Query: 572 ----EELEEAKRKLQ--ARLAEAEETIESLNQKVVALEKTKQRLATE 694
EE+E K ++ RL E E ES Q +A E ++RL E
Sbjct: 2032 KAALEEVERLKANVEEARRLRERAEQ-ESARQLQLAQEAAQKRLQAE 2077
>S73840-1|AAC13916.1| 231|Homo sapiens type IIA myosin heavy chain
protein.
Length = 231
Score = 54.8 bits (126), Expect = 3e-07
Identities = 43/178 (24%), Positives = 82/178 (46%), Gaps = 2/178 (1%)
Frame = +2
Query: 29 MGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSN-EKAAQEKIVKQLQHQLNEVQS 205
M E+L + A E+ + V DL+ LD +K +++L+ ++ E++
Sbjct: 61 MAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEG 120
Query: 206 KADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADE 385
+ + + + +K +L Q EE + +L + L +++ KR A+E
Sbjct: 121 EVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEE 180
Query: 386 EARERATLLGKFRNLEHDLDNIREQVEEEAEGKADL-QRQLSKANAEAQLWRSKYESE 556
+ T L KFR L+H+L EEAE +AD+ + Q++K +++ +K SE
Sbjct: 181 AEEQSNTNLAKFRKLQHEL--------EEAEERADIAESQVNKLRVKSREVHTKVISE 230
Score = 50.4 bits (115), Expect = 7e-06
Identities = 46/226 (20%), Positives = 98/226 (43%), Gaps = 2/226 (0%)
Frame = +2
Query: 26 DMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNE-KAAQEKIVKQLQHQLNEVQ 202
D E++ L+ + + ++++ ++ ++ + E + A+EK K + +
Sbjct: 4 DASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAE 63
Query: 203 SKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVS-LTTQLEDTKRLA 379
E + + + L+ KK + DL +L+EAE + K ++ L ++ + +
Sbjct: 64 ELKKEQDTSAH-LERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEV 122
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEG 559
+ E + A + R E + + Q EE+ + LQ + K A+ + ++ + E
Sbjct: 123 ESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAE 182
Query: 560 VARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEV 697
+ L + RKLQ L EAEE + +V L + + T+V
Sbjct: 183 EQSNTNLAKF-RKLQHELEEAEERADIAESQVNKLRVKSREVHTKV 227
Score = 35.9 bits (79), Expect = 0.16
Identities = 38/165 (23%), Positives = 72/165 (43%), Gaps = 3/165 (1%)
Frame = +2
Query: 239 LDAAKKK--LSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLL 412
LDA+++ L +N+ L+ ++ E+ +SQ+ + + + + A + + A +
Sbjct: 3 LDASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMA 62
Query: 413 GKFRNLEHDLDNIREQVEEEAEGKA-DLQRQLSKANAEAQLWRSKYESEGVARSEELEEA 589
+ + E D E++++ E DLQ +L +A A K + AR ELE
Sbjct: 63 EELKK-EQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGE 121
Query: 590 KRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
Q R AEA + + ++V L + + LQ VD+
Sbjct: 122 VESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDK 166
>AY480051-1|AAR95684.1| 4547|Homo sapiens plectin 11 protein.
Length = 4547
Score = 54.8 bits (126), Expect = 3e-07
Identities = 57/245 (23%), Positives = 107/245 (43%), Gaps = 15/245 (6%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV-QSKA 211
E L Q L K K + Q E L+A + L +K ++ ++LQ ++ Q A
Sbjct: 2299 EDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLA 2358
Query: 212 DEAN---RTLN-------DLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLE 361
+E RTL ++ A ++L + +++ R AE + K + +L
Sbjct: 2359 EETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLH 2418
Query: 362 DTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRS 541
T+ E+ TL + + +HD + +RE + A+L+R+ K EA+L +
Sbjct: 2419 RTELATQEKVTLVQTLEIQRQQSDHDAERLREAI-------AELEREKEKLQQEAKLLQL 2471
Query: 542 KYESEGVARSEE-LEEAKRKLQARLAEAEETIES---LNQKVVALEKTKQRLATEVEDLQ 709
K E + E+ L+E + Q+ L+E + ++ + Q+ LE+ Q + + L+
Sbjct: 2472 KSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLR 2531
Query: 710 LEVDR 724
E R
Sbjct: 2532 EEQQR 2536
Score = 44.8 bits (101), Expect = 4e-04
Identities = 47/196 (23%), Positives = 92/196 (46%), Gaps = 3/196 (1%)
Frame = +2
Query: 143 EKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAE-SQVS 319
E AQ+++ + + +++ E R L + + A+ + + RQ EAE ++V
Sbjct: 1702 EGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVR 1761
Query: 320 QLSKIKVSLTTQLEDTKRLADEEARERATL-LGKFRNLEHDLDNIREQVEEEAEGKADLQ 496
++ ++ + E+ R E++++R G+FR L + +R EE A Q
Sbjct: 1762 AEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEE-----AKRQ 1816
Query: 497 RQLSKANAEAQLWRSKYESEGVARSEELEEAKR-KLQARLAEAEETIESLNQKVVALEKT 673
RQL++ +A Q R++ E + + EA R K +A +A E+ E+ + +A ++
Sbjct: 1817 RQLAEEDAARQ--RAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEA 1874
Query: 674 KQRLATEVEDLQLEVD 721
QR E + Q + D
Sbjct: 1875 FQRRRLEEQAAQHKAD 1890
Score = 44.0 bits (99), Expect = 6e-04
Identities = 52/245 (21%), Positives = 110/245 (44%), Gaps = 18/245 (7%)
Frame = +2
Query: 38 QLDQLNKLKAKAEKXRAQY--FSEVNDLRAGLDHLSNE-KAAQEKIVKQLQHQLNEVQSK 208
+++ +++KA+AE R + + +LR + + A+ + +Q+Q L Q
Sbjct: 1514 EVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRS 1573
Query: 209 ADEANRTLNDLDAAKKKLSIENS---------DLLRQLEEAESQVSQLSKIKVSLTTQLE 361
A EA A+K +E S L + E Q ++ + + +LE
Sbjct: 1574 A-EAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELE 1632
Query: 362 DTKRLADEEARER--ATLLGKFRNL-EHDLDNIREQVEEEAE--GKADLQRQLSKANAEA 526
+ A+E R R A + + ++L + + + +E+ E EA GKA+ Q + AE
Sbjct: 1633 RWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQ 1692
Query: 527 QLWRSKYESEGVARSE-ELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVED 703
+L + + +EG A+ E+ +L+A + E+ + L +++ L++ + ++
Sbjct: 1693 ELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQE 1752
Query: 704 LQLEV 718
L+ E+
Sbjct: 1753 LEAEL 1757
Score = 43.6 bits (98), Expect = 8e-04
Identities = 56/227 (24%), Positives = 103/227 (45%), Gaps = 16/227 (7%)
Frame = +2
Query: 62 KAKAEKXRAQYFSEVND---LRAGLDHLSNEKAAQEKIVKQLQH----QLNEVQSKADEA 220
+A+AE+ A+ + + + L+ + EK A+ + +++L Q ++ +A +
Sbjct: 1828 RAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQH 1887
Query: 221 NRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARER 400
+ + A +K S +S+L RQ E + Q +++ + ++ A +A E
Sbjct: 1888 KADIEERLAQLRKAS--DSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKA-EL 1944
Query: 401 ATLLGKFRNLEHDLDNIREQVEEEAEGKADL--QRQLSKANAEAQLWRSKYESEGVARS- 571
LG+ R+ D +EQ E EA + L + + + AE ++ +S E AR
Sbjct: 1945 ELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQR 2004
Query: 572 ----EELEEAKRKLQ--ARLAEAEETIESLNQKVVALEKTKQRLATE 694
EE+E K K++ RL E E ES Q +A E ++RL E
Sbjct: 2005 KAALEEVERLKAKVEEARRLRERAEQ-ESARQLQLAQEAAQKRLQAE 2050
Score = 41.9 bits (94), Expect = 0.003
Identities = 60/245 (24%), Positives = 105/245 (42%), Gaps = 9/245 (3%)
Frame = +2
Query: 14 RFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLN 193
+++ + E L ++ + + AE+ RA+ + ++ A L+ A + Q + +
Sbjct: 1332 QYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAK 1391
Query: 194 EVQSKADE--ANRTLNDLDAAKKKLSI-ENSDLLRQLEEAESQVSQLSKIKVSLTTQLED 364
E+Q + E R +DA ++K SI E LRQ EAE Q
Sbjct: 1392 ELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQA---------------- 1435
Query: 365 TKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSK 544
+ EA ER+ L +E ++ +R Q+E +RQ A E Q R++
Sbjct: 1436 --KARQAEAAERSRL-----RIEEEIRVVRLQLEAT-------ERQRGGAEGELQALRAR 1481
Query: 545 -YESEGVAR--SEELEEAKRKLQ---ARLAEAEETIESLNQKVVALEKTKQRLATEVEDL 706
E+E R EE E +R++Q R +AE + S + + KQR +E+L
Sbjct: 1482 AEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEEL 1541
Query: 707 QLEVD 721
+L+ +
Sbjct: 1542 RLQAE 1546
>AY480050-1|AAR95683.1| 4551|Homo sapiens plectin 10 protein.
Length = 4551
Score = 54.8 bits (126), Expect = 3e-07
Identities = 57/245 (23%), Positives = 107/245 (43%), Gaps = 15/245 (6%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV-QSKA 211
E L Q L K K + Q E L+A + L +K ++ ++LQ ++ Q A
Sbjct: 2303 EDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLA 2362
Query: 212 DEAN---RTLN-------DLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLE 361
+E RTL ++ A ++L + +++ R AE + K + +L
Sbjct: 2363 EETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLH 2422
Query: 362 DTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRS 541
T+ E+ TL + + +HD + +RE + A+L+R+ K EA+L +
Sbjct: 2423 RTELATQEKVTLVQTLEIQRQQSDHDAERLREAI-------AELEREKEKLQQEAKLLQL 2475
Query: 542 KYESEGVARSEE-LEEAKRKLQARLAEAEETIES---LNQKVVALEKTKQRLATEVEDLQ 709
K E + E+ L+E + Q+ L+E + ++ + Q+ LE+ Q + + L+
Sbjct: 2476 KSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLR 2535
Query: 710 LEVDR 724
E R
Sbjct: 2536 EEQQR 2540
Score = 44.8 bits (101), Expect = 4e-04
Identities = 47/196 (23%), Positives = 92/196 (46%), Gaps = 3/196 (1%)
Frame = +2
Query: 143 EKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAE-SQVS 319
E AQ+++ + + +++ E R L + + A+ + + RQ EAE ++V
Sbjct: 1706 EGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVR 1765
Query: 320 QLSKIKVSLTTQLEDTKRLADEEARERATL-LGKFRNLEHDLDNIREQVEEEAEGKADLQ 496
++ ++ + E+ R E++++R G+FR L + +R EE A Q
Sbjct: 1766 AEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEE-----AKRQ 1820
Query: 497 RQLSKANAEAQLWRSKYESEGVARSEELEEAKR-KLQARLAEAEETIESLNQKVVALEKT 673
RQL++ +A Q R++ E + + EA R K +A +A E+ E+ + +A ++
Sbjct: 1821 RQLAEEDAARQ--RAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEA 1878
Query: 674 KQRLATEVEDLQLEVD 721
QR E + Q + D
Sbjct: 1879 FQRRRLEEQAAQHKAD 1894
Score = 44.0 bits (99), Expect = 6e-04
Identities = 52/245 (21%), Positives = 110/245 (44%), Gaps = 18/245 (7%)
Frame = +2
Query: 38 QLDQLNKLKAKAEKXRAQY--FSEVNDLRAGLDHLSNE-KAAQEKIVKQLQHQLNEVQSK 208
+++ +++KA+AE R + + +LR + + A+ + +Q+Q L Q
Sbjct: 1518 EVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRS 1577
Query: 209 ADEANRTLNDLDAAKKKLSIENS---------DLLRQLEEAESQVSQLSKIKVSLTTQLE 361
A EA A+K +E S L + E Q ++ + + +LE
Sbjct: 1578 A-EAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELE 1636
Query: 362 DTKRLADEEARER--ATLLGKFRNL-EHDLDNIREQVEEEAE--GKADLQRQLSKANAEA 526
+ A+E R R A + + ++L + + + +E+ E EA GKA+ Q + AE
Sbjct: 1637 RWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQ 1696
Query: 527 QLWRSKYESEGVARSE-ELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVED 703
+L + + +EG A+ E+ +L+A + E+ + L +++ L++ + ++
Sbjct: 1697 ELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQE 1756
Query: 704 LQLEV 718
L+ E+
Sbjct: 1757 LEAEL 1761
Score = 43.6 bits (98), Expect = 8e-04
Identities = 56/227 (24%), Positives = 103/227 (45%), Gaps = 16/227 (7%)
Frame = +2
Query: 62 KAKAEKXRAQYFSEVND---LRAGLDHLSNEKAAQEKIVKQLQH----QLNEVQSKADEA 220
+A+AE+ A+ + + + L+ + EK A+ + +++L Q ++ +A +
Sbjct: 1832 RAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQH 1891
Query: 221 NRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARER 400
+ + A +K S +S+L RQ E + Q +++ + ++ A +A E
Sbjct: 1892 KADIEERLAQLRKAS--DSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKA-EL 1948
Query: 401 ATLLGKFRNLEHDLDNIREQVEEEAEGKADL--QRQLSKANAEAQLWRSKYESEGVARS- 571
LG+ R+ D +EQ E EA + L + + + AE ++ +S E AR
Sbjct: 1949 ELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQR 2008
Query: 572 ----EELEEAKRKLQ--ARLAEAEETIESLNQKVVALEKTKQRLATE 694
EE+E K K++ RL E E ES Q +A E ++RL E
Sbjct: 2009 KAALEEVERLKAKVEEARRLRERAEQ-ESARQLQLAQEAAQKRLQAE 2054
Score = 41.9 bits (94), Expect = 0.003
Identities = 60/245 (24%), Positives = 105/245 (42%), Gaps = 9/245 (3%)
Frame = +2
Query: 14 RFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLN 193
+++ + E L ++ + + AE+ RA+ + ++ A L+ A + Q + +
Sbjct: 1336 QYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAK 1395
Query: 194 EVQSKADE--ANRTLNDLDAAKKKLSI-ENSDLLRQLEEAESQVSQLSKIKVSLTTQLED 364
E+Q + E R +DA ++K SI E LRQ EAE Q
Sbjct: 1396 ELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQA---------------- 1439
Query: 365 TKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSK 544
+ EA ER+ L +E ++ +R Q+E +RQ A E Q R++
Sbjct: 1440 --KARQAEAAERSRL-----RIEEEIRVVRLQLEAT-------ERQRGGAEGELQALRAR 1485
Query: 545 -YESEGVAR--SEELEEAKRKLQ---ARLAEAEETIESLNQKVVALEKTKQRLATEVEDL 706
E+E R EE E +R++Q R +AE + S + + KQR +E+L
Sbjct: 1486 AEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEEL 1545
Query: 707 QLEVD 721
+L+ +
Sbjct: 1546 RLQAE 1550
>AY480049-1|AAR95682.1| 4547|Homo sapiens plectin 8 protein.
Length = 4547
Score = 54.8 bits (126), Expect = 3e-07
Identities = 57/245 (23%), Positives = 107/245 (43%), Gaps = 15/245 (6%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV-QSKA 211
E L Q L K K + Q E L+A + L +K ++ ++LQ ++ Q A
Sbjct: 2299 EDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLA 2358
Query: 212 DEAN---RTLN-------DLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLE 361
+E RTL ++ A ++L + +++ R AE + K + +L
Sbjct: 2359 EETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLH 2418
Query: 362 DTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRS 541
T+ E+ TL + + +HD + +RE + A+L+R+ K EA+L +
Sbjct: 2419 RTELATQEKVTLVQTLEIQRQQSDHDAERLREAI-------AELEREKEKLQQEAKLLQL 2471
Query: 542 KYESEGVARSEE-LEEAKRKLQARLAEAEETIES---LNQKVVALEKTKQRLATEVEDLQ 709
K E + E+ L+E + Q+ L+E + ++ + Q+ LE+ Q + + L+
Sbjct: 2472 KSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLR 2531
Query: 710 LEVDR 724
E R
Sbjct: 2532 EEQQR 2536
Score = 44.8 bits (101), Expect = 4e-04
Identities = 47/196 (23%), Positives = 92/196 (46%), Gaps = 3/196 (1%)
Frame = +2
Query: 143 EKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAE-SQVS 319
E AQ+++ + + +++ E R L + + A+ + + RQ EAE ++V
Sbjct: 1702 EGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVR 1761
Query: 320 QLSKIKVSLTTQLEDTKRLADEEARERATL-LGKFRNLEHDLDNIREQVEEEAEGKADLQ 496
++ ++ + E+ R E++++R G+FR L + +R EE A Q
Sbjct: 1762 AEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEE-----AKRQ 1816
Query: 497 RQLSKANAEAQLWRSKYESEGVARSEELEEAKR-KLQARLAEAEETIESLNQKVVALEKT 673
RQL++ +A Q R++ E + + EA R K +A +A E+ E+ + +A ++
Sbjct: 1817 RQLAEEDAARQ--RAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEA 1874
Query: 674 KQRLATEVEDLQLEVD 721
QR E + Q + D
Sbjct: 1875 FQRRRLEEQAAQHKAD 1890
Score = 44.0 bits (99), Expect = 6e-04
Identities = 52/245 (21%), Positives = 110/245 (44%), Gaps = 18/245 (7%)
Frame = +2
Query: 38 QLDQLNKLKAKAEKXRAQY--FSEVNDLRAGLDHLSNE-KAAQEKIVKQLQHQLNEVQSK 208
+++ +++KA+AE R + + +LR + + A+ + +Q+Q L Q
Sbjct: 1514 EVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRS 1573
Query: 209 ADEANRTLNDLDAAKKKLSIENS---------DLLRQLEEAESQVSQLSKIKVSLTTQLE 361
A EA A+K +E S L + E Q ++ + + +LE
Sbjct: 1574 A-EAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELE 1632
Query: 362 DTKRLADEEARER--ATLLGKFRNL-EHDLDNIREQVEEEAE--GKADLQRQLSKANAEA 526
+ A+E R R A + + ++L + + + +E+ E EA GKA+ Q + AE
Sbjct: 1633 RWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQ 1692
Query: 527 QLWRSKYESEGVARSE-ELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVED 703
+L + + +EG A+ E+ +L+A + E+ + L +++ L++ + ++
Sbjct: 1693 ELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQE 1752
Query: 704 LQLEV 718
L+ E+
Sbjct: 1753 LEAEL 1757
Score = 43.6 bits (98), Expect = 8e-04
Identities = 56/227 (24%), Positives = 103/227 (45%), Gaps = 16/227 (7%)
Frame = +2
Query: 62 KAKAEKXRAQYFSEVND---LRAGLDHLSNEKAAQEKIVKQLQH----QLNEVQSKADEA 220
+A+AE+ A+ + + + L+ + EK A+ + +++L Q ++ +A +
Sbjct: 1828 RAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQH 1887
Query: 221 NRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARER 400
+ + A +K S +S+L RQ E + Q +++ + ++ A +A E
Sbjct: 1888 KADIEERLAQLRKAS--DSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKA-EL 1944
Query: 401 ATLLGKFRNLEHDLDNIREQVEEEAEGKADL--QRQLSKANAEAQLWRSKYESEGVARS- 571
LG+ R+ D +EQ E EA + L + + + AE ++ +S E AR
Sbjct: 1945 ELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQR 2004
Query: 572 ----EELEEAKRKLQ--ARLAEAEETIESLNQKVVALEKTKQRLATE 694
EE+E K K++ RL E E ES Q +A E ++RL E
Sbjct: 2005 KAALEEVERLKAKVEEARRLRERAEQ-ESARQLQLAQEAAQKRLQAE 2050
Score = 41.9 bits (94), Expect = 0.003
Identities = 60/245 (24%), Positives = 105/245 (42%), Gaps = 9/245 (3%)
Frame = +2
Query: 14 RFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLN 193
+++ + E L ++ + + AE+ RA+ + ++ A L+ A + Q + +
Sbjct: 1332 QYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAK 1391
Query: 194 EVQSKADE--ANRTLNDLDAAKKKLSI-ENSDLLRQLEEAESQVSQLSKIKVSLTTQLED 364
E+Q + E R +DA ++K SI E LRQ EAE Q
Sbjct: 1392 ELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQA---------------- 1435
Query: 365 TKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSK 544
+ EA ER+ L +E ++ +R Q+E +RQ A E Q R++
Sbjct: 1436 --KARQAEAAERSRL-----RIEEEIRVVRLQLEAT-------ERQRGGAEGELQALRAR 1481
Query: 545 -YESEGVAR--SEELEEAKRKLQ---ARLAEAEETIESLNQKVVALEKTKQRLATEVEDL 706
E+E R EE E +R++Q R +AE + S + + KQR +E+L
Sbjct: 1482 AEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEEL 1541
Query: 707 QLEVD 721
+L+ +
Sbjct: 1542 RLQAE 1546
>AY480048-1|AAR95681.1| 4515|Homo sapiens plectin 7 protein.
Length = 4515
Score = 54.8 bits (126), Expect = 3e-07
Identities = 57/245 (23%), Positives = 107/245 (43%), Gaps = 15/245 (6%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV-QSKA 211
E L Q L K K + Q E L+A + L +K ++ ++LQ ++ Q A
Sbjct: 2267 EDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLA 2326
Query: 212 DEAN---RTLN-------DLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLE 361
+E RTL ++ A ++L + +++ R AE + K + +L
Sbjct: 2327 EETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLH 2386
Query: 362 DTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRS 541
T+ E+ TL + + +HD + +RE + A+L+R+ K EA+L +
Sbjct: 2387 RTELATQEKVTLVQTLEIQRQQSDHDAERLREAI-------AELEREKEKLQQEAKLLQL 2439
Query: 542 KYESEGVARSEE-LEEAKRKLQARLAEAEETIES---LNQKVVALEKTKQRLATEVEDLQ 709
K E + E+ L+E + Q+ L+E + ++ + Q+ LE+ Q + + L+
Sbjct: 2440 KSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLR 2499
Query: 710 LEVDR 724
E R
Sbjct: 2500 EEQQR 2504
Score = 44.8 bits (101), Expect = 4e-04
Identities = 47/196 (23%), Positives = 92/196 (46%), Gaps = 3/196 (1%)
Frame = +2
Query: 143 EKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAE-SQVS 319
E AQ+++ + + +++ E R L + + A+ + + RQ EAE ++V
Sbjct: 1670 EGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVR 1729
Query: 320 QLSKIKVSLTTQLEDTKRLADEEARERATL-LGKFRNLEHDLDNIREQVEEEAEGKADLQ 496
++ ++ + E+ R E++++R G+FR L + +R EE A Q
Sbjct: 1730 AEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEE-----AKRQ 1784
Query: 497 RQLSKANAEAQLWRSKYESEGVARSEELEEAKR-KLQARLAEAEETIESLNQKVVALEKT 673
RQL++ +A Q R++ E + + EA R K +A +A E+ E+ + +A ++
Sbjct: 1785 RQLAEEDAARQ--RAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEA 1842
Query: 674 KQRLATEVEDLQLEVD 721
QR E + Q + D
Sbjct: 1843 FQRRRLEEQAAQHKAD 1858
Score = 44.0 bits (99), Expect = 6e-04
Identities = 52/245 (21%), Positives = 110/245 (44%), Gaps = 18/245 (7%)
Frame = +2
Query: 38 QLDQLNKLKAKAEKXRAQY--FSEVNDLRAGLDHLSNE-KAAQEKIVKQLQHQLNEVQSK 208
+++ +++KA+AE R + + +LR + + A+ + +Q+Q L Q
Sbjct: 1482 EVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRS 1541
Query: 209 ADEANRTLNDLDAAKKKLSIENS---------DLLRQLEEAESQVSQLSKIKVSLTTQLE 361
A EA A+K +E S L + E Q ++ + + +LE
Sbjct: 1542 A-EAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELE 1600
Query: 362 DTKRLADEEARER--ATLLGKFRNL-EHDLDNIREQVEEEAE--GKADLQRQLSKANAEA 526
+ A+E R R A + + ++L + + + +E+ E EA GKA+ Q + AE
Sbjct: 1601 RWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQ 1660
Query: 527 QLWRSKYESEGVARSE-ELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVED 703
+L + + +EG A+ E+ +L+A + E+ + L +++ L++ + ++
Sbjct: 1661 ELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQE 1720
Query: 704 LQLEV 718
L+ E+
Sbjct: 1721 LEAEL 1725
Score = 43.6 bits (98), Expect = 8e-04
Identities = 56/227 (24%), Positives = 103/227 (45%), Gaps = 16/227 (7%)
Frame = +2
Query: 62 KAKAEKXRAQYFSEVND---LRAGLDHLSNEKAAQEKIVKQLQH----QLNEVQSKADEA 220
+A+AE+ A+ + + + L+ + EK A+ + +++L Q ++ +A +
Sbjct: 1796 RAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQH 1855
Query: 221 NRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARER 400
+ + A +K S +S+L RQ E + Q +++ + ++ A +A E
Sbjct: 1856 KADIEERLAQLRKAS--DSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKA-EL 1912
Query: 401 ATLLGKFRNLEHDLDNIREQVEEEAEGKADL--QRQLSKANAEAQLWRSKYESEGVARS- 571
LG+ R+ D +EQ E EA + L + + + AE ++ +S E AR
Sbjct: 1913 ELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQR 1972
Query: 572 ----EELEEAKRKLQ--ARLAEAEETIESLNQKVVALEKTKQRLATE 694
EE+E K K++ RL E E ES Q +A E ++RL E
Sbjct: 1973 KAALEEVERLKAKVEEARRLRERAEQ-ESARQLQLAQEAAQKRLQAE 2018
Score = 41.9 bits (94), Expect = 0.003
Identities = 60/245 (24%), Positives = 105/245 (42%), Gaps = 9/245 (3%)
Frame = +2
Query: 14 RFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLN 193
+++ + E L ++ + + AE+ RA+ + ++ A L+ A + Q + +
Sbjct: 1300 QYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAK 1359
Query: 194 EVQSKADE--ANRTLNDLDAAKKKLSI-ENSDLLRQLEEAESQVSQLSKIKVSLTTQLED 364
E+Q + E R +DA ++K SI E LRQ EAE Q
Sbjct: 1360 ELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQA---------------- 1403
Query: 365 TKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSK 544
+ EA ER+ L +E ++ +R Q+E +RQ A E Q R++
Sbjct: 1404 --KARQAEAAERSRL-----RIEEEIRVVRLQLEAT-------ERQRGGAEGELQALRAR 1449
Query: 545 -YESEGVAR--SEELEEAKRKLQ---ARLAEAEETIESLNQKVVALEKTKQRLATEVEDL 706
E+E R EE E +R++Q R +AE + S + + KQR +E+L
Sbjct: 1450 AEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEEL 1509
Query: 707 QLEVD 721
+L+ +
Sbjct: 1510 RLQAE 1514
>AY480047-1|AAR95680.1| 4684|Homo sapiens plectin 6 protein.
Length = 4684
Score = 54.8 bits (126), Expect = 3e-07
Identities = 57/245 (23%), Positives = 107/245 (43%), Gaps = 15/245 (6%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV-QSKA 211
E L Q L K K + Q E L+A + L +K ++ ++LQ ++ Q A
Sbjct: 2436 EDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLA 2495
Query: 212 DEAN---RTLN-------DLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLE 361
+E RTL ++ A ++L + +++ R AE + K + +L
Sbjct: 2496 EETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLH 2555
Query: 362 DTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRS 541
T+ E+ TL + + +HD + +RE + A+L+R+ K EA+L +
Sbjct: 2556 RTELATQEKVTLVQTLEIQRQQSDHDAERLREAI-------AELEREKEKLQQEAKLLQL 2608
Query: 542 KYESEGVARSEE-LEEAKRKLQARLAEAEETIES---LNQKVVALEKTKQRLATEVEDLQ 709
K E + E+ L+E + Q+ L+E + ++ + Q+ LE+ Q + + L+
Sbjct: 2609 KSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLR 2668
Query: 710 LEVDR 724
E R
Sbjct: 2669 EEQQR 2673
Score = 44.8 bits (101), Expect = 4e-04
Identities = 47/196 (23%), Positives = 92/196 (46%), Gaps = 3/196 (1%)
Frame = +2
Query: 143 EKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAE-SQVS 319
E AQ+++ + + +++ E R L + + A+ + + RQ EAE ++V
Sbjct: 1839 EGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVR 1898
Query: 320 QLSKIKVSLTTQLEDTKRLADEEARERATL-LGKFRNLEHDLDNIREQVEEEAEGKADLQ 496
++ ++ + E+ R E++++R G+FR L + +R EE A Q
Sbjct: 1899 AEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEE-----AKRQ 1953
Query: 497 RQLSKANAEAQLWRSKYESEGVARSEELEEAKR-KLQARLAEAEETIESLNQKVVALEKT 673
RQL++ +A Q R++ E + + EA R K +A +A E+ E+ + +A ++
Sbjct: 1954 RQLAEEDAARQ--RAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEA 2011
Query: 674 KQRLATEVEDLQLEVD 721
QR E + Q + D
Sbjct: 2012 FQRRRLEEQAAQHKAD 2027
Score = 44.0 bits (99), Expect = 6e-04
Identities = 52/245 (21%), Positives = 110/245 (44%), Gaps = 18/245 (7%)
Frame = +2
Query: 38 QLDQLNKLKAKAEKXRAQY--FSEVNDLRAGLDHLSNE-KAAQEKIVKQLQHQLNEVQSK 208
+++ +++KA+AE R + + +LR + + A+ + +Q+Q L Q
Sbjct: 1651 EVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRS 1710
Query: 209 ADEANRTLNDLDAAKKKLSIENS---------DLLRQLEEAESQVSQLSKIKVSLTTQLE 361
A EA A+K +E S L + E Q ++ + + +LE
Sbjct: 1711 A-EAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELE 1769
Query: 362 DTKRLADEEARER--ATLLGKFRNL-EHDLDNIREQVEEEAE--GKADLQRQLSKANAEA 526
+ A+E R R A + + ++L + + + +E+ E EA GKA+ Q + AE
Sbjct: 1770 RWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQ 1829
Query: 527 QLWRSKYESEGVARSE-ELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVED 703
+L + + +EG A+ E+ +L+A + E+ + L +++ L++ + ++
Sbjct: 1830 ELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQE 1889
Query: 704 LQLEV 718
L+ E+
Sbjct: 1890 LEAEL 1894
Score = 43.6 bits (98), Expect = 8e-04
Identities = 56/227 (24%), Positives = 103/227 (45%), Gaps = 16/227 (7%)
Frame = +2
Query: 62 KAKAEKXRAQYFSEVND---LRAGLDHLSNEKAAQEKIVKQLQH----QLNEVQSKADEA 220
+A+AE+ A+ + + + L+ + EK A+ + +++L Q ++ +A +
Sbjct: 1965 RAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQH 2024
Query: 221 NRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARER 400
+ + A +K S +S+L RQ E + Q +++ + ++ A +A E
Sbjct: 2025 KADIEERLAQLRKAS--DSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKA-EL 2081
Query: 401 ATLLGKFRNLEHDLDNIREQVEEEAEGKADL--QRQLSKANAEAQLWRSKYESEGVARS- 571
LG+ R+ D +EQ E EA + L + + + AE ++ +S E AR
Sbjct: 2082 ELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQR 2141
Query: 572 ----EELEEAKRKLQ--ARLAEAEETIESLNQKVVALEKTKQRLATE 694
EE+E K K++ RL E E ES Q +A E ++RL E
Sbjct: 2142 KAALEEVERLKAKVEEARRLRERAEQ-ESARQLQLAQEAAQKRLQAE 2187
Score = 41.9 bits (94), Expect = 0.003
Identities = 60/245 (24%), Positives = 105/245 (42%), Gaps = 9/245 (3%)
Frame = +2
Query: 14 RFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLN 193
+++ + E L ++ + + AE+ RA+ + ++ A L+ A + Q + +
Sbjct: 1469 QYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAK 1528
Query: 194 EVQSKADE--ANRTLNDLDAAKKKLSI-ENSDLLRQLEEAESQVSQLSKIKVSLTTQLED 364
E+Q + E R +DA ++K SI E LRQ EAE Q
Sbjct: 1529 ELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQA---------------- 1572
Query: 365 TKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSK 544
+ EA ER+ L +E ++ +R Q+E +RQ A E Q R++
Sbjct: 1573 --KARQAEAAERSRL-----RIEEEIRVVRLQLEAT-------ERQRGGAEGELQALRAR 1618
Query: 545 -YESEGVAR--SEELEEAKRKLQ---ARLAEAEETIESLNQKVVALEKTKQRLATEVEDL 706
E+E R EE E +R++Q R +AE + S + + KQR +E+L
Sbjct: 1619 AEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEEL 1678
Query: 707 QLEVD 721
+L+ +
Sbjct: 1679 RLQAE 1683
>AY480046-1|AAR95679.1| 4525|Homo sapiens plectin 3 protein.
Length = 4525
Score = 54.8 bits (126), Expect = 3e-07
Identities = 57/245 (23%), Positives = 107/245 (43%), Gaps = 15/245 (6%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV-QSKA 211
E L Q L K K + Q E L+A + L +K ++ ++LQ ++ Q A
Sbjct: 2277 EDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLA 2336
Query: 212 DEAN---RTLN-------DLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLE 361
+E RTL ++ A ++L + +++ R AE + K + +L
Sbjct: 2337 EETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLH 2396
Query: 362 DTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRS 541
T+ E+ TL + + +HD + +RE + A+L+R+ K EA+L +
Sbjct: 2397 RTELATQEKVTLVQTLEIQRQQSDHDAERLREAI-------AELEREKEKLQQEAKLLQL 2449
Query: 542 KYESEGVARSEE-LEEAKRKLQARLAEAEETIES---LNQKVVALEKTKQRLATEVEDLQ 709
K E + E+ L+E + Q+ L+E + ++ + Q+ LE+ Q + + L+
Sbjct: 2450 KSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLR 2509
Query: 710 LEVDR 724
E R
Sbjct: 2510 EEQQR 2514
Score = 44.8 bits (101), Expect = 4e-04
Identities = 47/196 (23%), Positives = 92/196 (46%), Gaps = 3/196 (1%)
Frame = +2
Query: 143 EKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAE-SQVS 319
E AQ+++ + + +++ E R L + + A+ + + RQ EAE ++V
Sbjct: 1680 EGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVR 1739
Query: 320 QLSKIKVSLTTQLEDTKRLADEEARERATL-LGKFRNLEHDLDNIREQVEEEAEGKADLQ 496
++ ++ + E+ R E++++R G+FR L + +R EE A Q
Sbjct: 1740 AEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEE-----AKRQ 1794
Query: 497 RQLSKANAEAQLWRSKYESEGVARSEELEEAKR-KLQARLAEAEETIESLNQKVVALEKT 673
RQL++ +A Q R++ E + + EA R K +A +A E+ E+ + +A ++
Sbjct: 1795 RQLAEEDAARQ--RAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEA 1852
Query: 674 KQRLATEVEDLQLEVD 721
QR E + Q + D
Sbjct: 1853 FQRRRLEEQAAQHKAD 1868
Score = 44.0 bits (99), Expect = 6e-04
Identities = 52/245 (21%), Positives = 110/245 (44%), Gaps = 18/245 (7%)
Frame = +2
Query: 38 QLDQLNKLKAKAEKXRAQY--FSEVNDLRAGLDHLSNE-KAAQEKIVKQLQHQLNEVQSK 208
+++ +++KA+AE R + + +LR + + A+ + +Q+Q L Q
Sbjct: 1492 EVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRS 1551
Query: 209 ADEANRTLNDLDAAKKKLSIENS---------DLLRQLEEAESQVSQLSKIKVSLTTQLE 361
A EA A+K +E S L + E Q ++ + + +LE
Sbjct: 1552 A-EAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELE 1610
Query: 362 DTKRLADEEARER--ATLLGKFRNL-EHDLDNIREQVEEEAE--GKADLQRQLSKANAEA 526
+ A+E R R A + + ++L + + + +E+ E EA GKA+ Q + AE
Sbjct: 1611 RWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQ 1670
Query: 527 QLWRSKYESEGVARSE-ELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVED 703
+L + + +EG A+ E+ +L+A + E+ + L +++ L++ + ++
Sbjct: 1671 ELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQE 1730
Query: 704 LQLEV 718
L+ E+
Sbjct: 1731 LEAEL 1735
Score = 43.6 bits (98), Expect = 8e-04
Identities = 56/227 (24%), Positives = 103/227 (45%), Gaps = 16/227 (7%)
Frame = +2
Query: 62 KAKAEKXRAQYFSEVND---LRAGLDHLSNEKAAQEKIVKQLQH----QLNEVQSKADEA 220
+A+AE+ A+ + + + L+ + EK A+ + +++L Q ++ +A +
Sbjct: 1806 RAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQH 1865
Query: 221 NRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARER 400
+ + A +K S +S+L RQ E + Q +++ + ++ A +A E
Sbjct: 1866 KADIEERLAQLRKAS--DSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKA-EL 1922
Query: 401 ATLLGKFRNLEHDLDNIREQVEEEAEGKADL--QRQLSKANAEAQLWRSKYESEGVARS- 571
LG+ R+ D +EQ E EA + L + + + AE ++ +S E AR
Sbjct: 1923 ELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQR 1982
Query: 572 ----EELEEAKRKLQ--ARLAEAEETIESLNQKVVALEKTKQRLATE 694
EE+E K K++ RL E E ES Q +A E ++RL E
Sbjct: 1983 KAALEEVERLKAKVEEARRLRERAEQ-ESARQLQLAQEAAQKRLQAE 2028
Score = 41.9 bits (94), Expect = 0.003
Identities = 60/245 (24%), Positives = 105/245 (42%), Gaps = 9/245 (3%)
Frame = +2
Query: 14 RFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLN 193
+++ + E L ++ + + AE+ RA+ + ++ A L+ A + Q + +
Sbjct: 1310 QYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAK 1369
Query: 194 EVQSKADE--ANRTLNDLDAAKKKLSI-ENSDLLRQLEEAESQVSQLSKIKVSLTTQLED 364
E+Q + E R +DA ++K SI E LRQ EAE Q
Sbjct: 1370 ELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQA---------------- 1413
Query: 365 TKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSK 544
+ EA ER+ L +E ++ +R Q+E +RQ A E Q R++
Sbjct: 1414 --KARQAEAAERSRL-----RIEEEIRVVRLQLEAT-------ERQRGGAEGELQALRAR 1459
Query: 545 -YESEGVAR--SEELEEAKRKLQ---ARLAEAEETIESLNQKVVALEKTKQRLATEVEDL 706
E+E R EE E +R++Q R +AE + S + + KQR +E+L
Sbjct: 1460 AEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEEL 1519
Query: 707 QLEVD 721
+L+ +
Sbjct: 1520 RLQAE 1524
>AY480045-1|AAR95678.1| 4533|Homo sapiens plectin 2 protein.
Length = 4533
Score = 54.8 bits (126), Expect = 3e-07
Identities = 57/245 (23%), Positives = 107/245 (43%), Gaps = 15/245 (6%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV-QSKA 211
E L Q L K K + Q E L+A + L +K ++ ++LQ ++ Q A
Sbjct: 2285 EDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLA 2344
Query: 212 DEAN---RTLN-------DLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLE 361
+E RTL ++ A ++L + +++ R AE + K + +L
Sbjct: 2345 EETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLH 2404
Query: 362 DTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRS 541
T+ E+ TL + + +HD + +RE + A+L+R+ K EA+L +
Sbjct: 2405 RTELATQEKVTLVQTLEIQRQQSDHDAERLREAI-------AELEREKEKLQQEAKLLQL 2457
Query: 542 KYESEGVARSEE-LEEAKRKLQARLAEAEETIES---LNQKVVALEKTKQRLATEVEDLQ 709
K E + E+ L+E + Q+ L+E + ++ + Q+ LE+ Q + + L+
Sbjct: 2458 KSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLR 2517
Query: 710 LEVDR 724
E R
Sbjct: 2518 EEQQR 2522
Score = 44.8 bits (101), Expect = 4e-04
Identities = 47/196 (23%), Positives = 92/196 (46%), Gaps = 3/196 (1%)
Frame = +2
Query: 143 EKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAE-SQVS 319
E AQ+++ + + +++ E R L + + A+ + + RQ EAE ++V
Sbjct: 1688 EGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVR 1747
Query: 320 QLSKIKVSLTTQLEDTKRLADEEARERATL-LGKFRNLEHDLDNIREQVEEEAEGKADLQ 496
++ ++ + E+ R E++++R G+FR L + +R EE A Q
Sbjct: 1748 AEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEE-----AKRQ 1802
Query: 497 RQLSKANAEAQLWRSKYESEGVARSEELEEAKR-KLQARLAEAEETIESLNQKVVALEKT 673
RQL++ +A Q R++ E + + EA R K +A +A E+ E+ + +A ++
Sbjct: 1803 RQLAEEDAARQ--RAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEA 1860
Query: 674 KQRLATEVEDLQLEVD 721
QR E + Q + D
Sbjct: 1861 FQRRRLEEQAAQHKAD 1876
Score = 44.0 bits (99), Expect = 6e-04
Identities = 52/245 (21%), Positives = 110/245 (44%), Gaps = 18/245 (7%)
Frame = +2
Query: 38 QLDQLNKLKAKAEKXRAQY--FSEVNDLRAGLDHLSNE-KAAQEKIVKQLQHQLNEVQSK 208
+++ +++KA+AE R + + +LR + + A+ + +Q+Q L Q
Sbjct: 1500 EVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRS 1559
Query: 209 ADEANRTLNDLDAAKKKLSIENS---------DLLRQLEEAESQVSQLSKIKVSLTTQLE 361
A EA A+K +E S L + E Q ++ + + +LE
Sbjct: 1560 A-EAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELE 1618
Query: 362 DTKRLADEEARER--ATLLGKFRNL-EHDLDNIREQVEEEAE--GKADLQRQLSKANAEA 526
+ A+E R R A + + ++L + + + +E+ E EA GKA+ Q + AE
Sbjct: 1619 RWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQ 1678
Query: 527 QLWRSKYESEGVARSE-ELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVED 703
+L + + +EG A+ E+ +L+A + E+ + L +++ L++ + ++
Sbjct: 1679 ELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQE 1738
Query: 704 LQLEV 718
L+ E+
Sbjct: 1739 LEAEL 1743
Score = 43.6 bits (98), Expect = 8e-04
Identities = 56/227 (24%), Positives = 103/227 (45%), Gaps = 16/227 (7%)
Frame = +2
Query: 62 KAKAEKXRAQYFSEVND---LRAGLDHLSNEKAAQEKIVKQLQH----QLNEVQSKADEA 220
+A+AE+ A+ + + + L+ + EK A+ + +++L Q ++ +A +
Sbjct: 1814 RAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQH 1873
Query: 221 NRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARER 400
+ + A +K S +S+L RQ E + Q +++ + ++ A +A E
Sbjct: 1874 KADIEERLAQLRKAS--DSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKA-EL 1930
Query: 401 ATLLGKFRNLEHDLDNIREQVEEEAEGKADL--QRQLSKANAEAQLWRSKYESEGVARS- 571
LG+ R+ D +EQ E EA + L + + + AE ++ +S E AR
Sbjct: 1931 ELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQR 1990
Query: 572 ----EELEEAKRKLQ--ARLAEAEETIESLNQKVVALEKTKQRLATE 694
EE+E K K++ RL E E ES Q +A E ++RL E
Sbjct: 1991 KAALEEVERLKAKVEEARRLRERAEQ-ESARQLQLAQEAAQKRLQAE 2036
Score = 41.9 bits (94), Expect = 0.003
Identities = 60/245 (24%), Positives = 105/245 (42%), Gaps = 9/245 (3%)
Frame = +2
Query: 14 RFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLN 193
+++ + E L ++ + + AE+ RA+ + ++ A L+ A + Q + +
Sbjct: 1318 QYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAK 1377
Query: 194 EVQSKADE--ANRTLNDLDAAKKKLSI-ENSDLLRQLEEAESQVSQLSKIKVSLTTQLED 364
E+Q + E R +DA ++K SI E LRQ EAE Q
Sbjct: 1378 ELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQA---------------- 1421
Query: 365 TKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSK 544
+ EA ER+ L +E ++ +R Q+E +RQ A E Q R++
Sbjct: 1422 --KARQAEAAERSRL-----RIEEEIRVVRLQLEAT-------ERQRGGAEGELQALRAR 1467
Query: 545 -YESEGVAR--SEELEEAKRKLQ---ARLAEAEETIESLNQKVVALEKTKQRLATEVEDL 706
E+E R EE E +R++Q R +AE + S + + KQR +E+L
Sbjct: 1468 AEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEEL 1527
Query: 707 QLEVD 721
+L+ +
Sbjct: 1528 RLQAE 1532
>AY480044-1|AAR95677.1| 4574|Homo sapiens plectin 1 protein.
Length = 4574
Score = 54.8 bits (126), Expect = 3e-07
Identities = 57/245 (23%), Positives = 107/245 (43%), Gaps = 15/245 (6%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV-QSKA 211
E L Q L K K + Q E L+A + L +K ++ ++LQ ++ Q A
Sbjct: 2326 EDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLA 2385
Query: 212 DEAN---RTLN-------DLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLE 361
+E RTL ++ A ++L + +++ R AE + K + +L
Sbjct: 2386 EETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLH 2445
Query: 362 DTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRS 541
T+ E+ TL + + +HD + +RE + A+L+R+ K EA+L +
Sbjct: 2446 RTELATQEKVTLVQTLEIQRQQSDHDAERLREAI-------AELEREKEKLQQEAKLLQL 2498
Query: 542 KYESEGVARSEE-LEEAKRKLQARLAEAEETIES---LNQKVVALEKTKQRLATEVEDLQ 709
K E + E+ L+E + Q+ L+E + ++ + Q+ LE+ Q + + L+
Sbjct: 2499 KSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLR 2558
Query: 710 LEVDR 724
E R
Sbjct: 2559 EEQQR 2563
Score = 44.8 bits (101), Expect = 4e-04
Identities = 47/196 (23%), Positives = 92/196 (46%), Gaps = 3/196 (1%)
Frame = +2
Query: 143 EKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAE-SQVS 319
E AQ+++ + + +++ E R L + + A+ + + RQ EAE ++V
Sbjct: 1729 EGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVR 1788
Query: 320 QLSKIKVSLTTQLEDTKRLADEEARERATL-LGKFRNLEHDLDNIREQVEEEAEGKADLQ 496
++ ++ + E+ R E++++R G+FR L + +R EE A Q
Sbjct: 1789 AEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEE-----AKRQ 1843
Query: 497 RQLSKANAEAQLWRSKYESEGVARSEELEEAKR-KLQARLAEAEETIESLNQKVVALEKT 673
RQL++ +A Q R++ E + + EA R K +A +A E+ E+ + +A ++
Sbjct: 1844 RQLAEEDAARQ--RAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEA 1901
Query: 674 KQRLATEVEDLQLEVD 721
QR E + Q + D
Sbjct: 1902 FQRRRLEEQAAQHKAD 1917
Score = 44.0 bits (99), Expect = 6e-04
Identities = 52/245 (21%), Positives = 110/245 (44%), Gaps = 18/245 (7%)
Frame = +2
Query: 38 QLDQLNKLKAKAEKXRAQY--FSEVNDLRAGLDHLSNE-KAAQEKIVKQLQHQLNEVQSK 208
+++ +++KA+AE R + + +LR + + A+ + +Q+Q L Q
Sbjct: 1541 EVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRS 1600
Query: 209 ADEANRTLNDLDAAKKKLSIENS---------DLLRQLEEAESQVSQLSKIKVSLTTQLE 361
A EA A+K +E S L + E Q ++ + + +LE
Sbjct: 1601 A-EAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELE 1659
Query: 362 DTKRLADEEARER--ATLLGKFRNL-EHDLDNIREQVEEEAE--GKADLQRQLSKANAEA 526
+ A+E R R A + + ++L + + + +E+ E EA GKA+ Q + AE
Sbjct: 1660 RWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQ 1719
Query: 527 QLWRSKYESEGVARSE-ELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVED 703
+L + + +EG A+ E+ +L+A + E+ + L +++ L++ + ++
Sbjct: 1720 ELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQE 1779
Query: 704 LQLEV 718
L+ E+
Sbjct: 1780 LEAEL 1784
Score = 43.6 bits (98), Expect = 8e-04
Identities = 56/227 (24%), Positives = 103/227 (45%), Gaps = 16/227 (7%)
Frame = +2
Query: 62 KAKAEKXRAQYFSEVND---LRAGLDHLSNEKAAQEKIVKQLQH----QLNEVQSKADEA 220
+A+AE+ A+ + + + L+ + EK A+ + +++L Q ++ +A +
Sbjct: 1855 RAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQH 1914
Query: 221 NRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARER 400
+ + A +K S +S+L RQ E + Q +++ + ++ A +A E
Sbjct: 1915 KADIEERLAQLRKAS--DSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKA-EL 1971
Query: 401 ATLLGKFRNLEHDLDNIREQVEEEAEGKADL--QRQLSKANAEAQLWRSKYESEGVARS- 571
LG+ R+ D +EQ E EA + L + + + AE ++ +S E AR
Sbjct: 1972 ELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQR 2031
Query: 572 ----EELEEAKRKLQ--ARLAEAEETIESLNQKVVALEKTKQRLATE 694
EE+E K K++ RL E E ES Q +A E ++RL E
Sbjct: 2032 KAALEEVERLKAKVEEARRLRERAEQ-ESARQLQLAQEAAQKRLQAE 2077
Score = 41.9 bits (94), Expect = 0.003
Identities = 60/245 (24%), Positives = 105/245 (42%), Gaps = 9/245 (3%)
Frame = +2
Query: 14 RFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLN 193
+++ + E L ++ + + AE+ RA+ + ++ A L+ A + Q + +
Sbjct: 1359 QYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAK 1418
Query: 194 EVQSKADE--ANRTLNDLDAAKKKLSI-ENSDLLRQLEEAESQVSQLSKIKVSLTTQLED 364
E+Q + E R +DA ++K SI E LRQ EAE Q
Sbjct: 1419 ELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQA---------------- 1462
Query: 365 TKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSK 544
+ EA ER+ L +E ++ +R Q+E +RQ A E Q R++
Sbjct: 1463 --KARQAEAAERSRL-----RIEEEIRVVRLQLEAT-------ERQRGGAEGELQALRAR 1508
Query: 545 -YESEGVAR--SEELEEAKRKLQ---ARLAEAEETIESLNQKVVALEKTKQRLATEVEDL 706
E+E R EE E +R++Q R +AE + S + + KQR +E+L
Sbjct: 1509 AEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEEL 1568
Query: 707 QLEVD 721
+L+ +
Sbjct: 1569 RLQAE 1573
>AL121586-7|CAB89415.1| 2442|Homo sapiens centrosomal protein 250kDa
protein.
Length = 2442
Score = 54.8 bits (126), Expect = 3e-07
Identities = 59/230 (25%), Positives = 108/230 (46%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD 214
+Q+ +L + E ++Q +E+ DL+ L EK+ E KQ N ++S+
Sbjct: 1264 DQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEG--KQ-----NSLESELM 1316
Query: 215 EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEAR 394
E + T+ L + ++ ++ EA+ + L K +LT Q+E + A EAR
Sbjct: 1317 ELHETMASLQSRLRRAELQRM-------EAQGERELLQAAKENLTAQVEHLQA-AVVEAR 1368
Query: 395 ERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSE 574
+A+ G LE DL R ++ + E +++ + +A A + K VA+ +
Sbjct: 1369 AQASAAGI---LEEDLRTARSALKLKNE---EVESERERAQALQEQGELK-----VAQGK 1417
Query: 575 ELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
L+E L LAE EE +E+L ++ LEK ++ +E L L++ +
Sbjct: 1418 ALQENLALLTQTLAEREEEVETLRGQIQELEKQREMQKAALELLSLDLKK 1467
Score = 53.2 bits (122), Expect = 1e-06
Identities = 59/237 (24%), Positives = 105/237 (44%), Gaps = 16/237 (6%)
Frame = +2
Query: 44 DQLNKLKAKAEKXRAQYFSEVNDLRAGLD--HLSNEKAAQEKI-----VKQLQHQLNEVQ 202
++L ++ E +++ SE+ LR L+ HL E QE+ + + + + E+
Sbjct: 522 ERLQEMLMGLEAKQSESLSELITLREALESSHLEGELLRQEQTEVTAALARAEQSIAELS 581
Query: 203 SKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKR--- 373
S + + DL AA KLS N L Q+ QL + S+ +++E ++
Sbjct: 582 SSENTLKTEVADLRAAAVKLSALNEALALDKVGLNQQLLQLEEENQSVCSRMEAAEQARN 641
Query: 374 -----LADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWR 538
LA+ E R A L K +LE L E E D+Q + K + +L
Sbjct: 642 ALQVDLAEAEKRREA-LWEKNTHLEAQLQKAEEAGAELQADLRDIQEE--KEEIQKKLSE 698
Query: 539 SKYESEGVARS-EELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDL 706
S+++ E E+L + ++ + LA A + E+L ++ ALE Q + + +DL
Sbjct: 699 SRHQQEAATTQLEQLHQEAKRQEEVLARAVQEKEALVREKAALEVRLQAVERDRQDL 755
Score = 52.4 bits (120), Expect = 2e-06
Identities = 46/207 (22%), Positives = 95/207 (45%), Gaps = 9/207 (4%)
Frame = +2
Query: 131 HLS-NEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAE 307
HL+ E+ ++++ L+ + +E S+ L + L E +++ L AE
Sbjct: 515 HLAVRERERLQEMLMGLEAKQSESLSELITLREALESSHLEGELLRQEQTEVTAALARAE 574
Query: 308 SQVSQLSKIKVSLTTQLEDTKRLA-------DEEARERATLLGKFRNLEHDLDNIREQVE 466
+++LS + +L T++ D + A + A ++ L + LE + ++ ++E
Sbjct: 575 QSIAELSSSENTLKTEVADLRAAAVKLSALNEALALDKVGLNQQLLQLEEENQSVCSRME 634
Query: 467 EEAEGKADLQRQLSKANAEAQ-LWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESL 643
+ + LQ L++A + LW E A+ ++ EEA +LQA L + +E E +
Sbjct: 635 AAEQARNALQVDLAEAEKRREALWEKNTHLE--AQLQKAEEAGAELQADLRDIQEEKEEI 692
Query: 644 NQKVVALEKTKQRLATEVEDLQLEVDR 724
+K+ ++ T++E L E R
Sbjct: 693 QKKLSESRHQQEAATTQLEQLHQEAKR 719
Score = 50.0 bits (114), Expect = 9e-06
Identities = 53/202 (26%), Positives = 87/202 (43%), Gaps = 9/202 (4%)
Frame = +2
Query: 146 KAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQL 325
+A QEK + EV+ +A E +R DL + LS L L EA+ Q S +
Sbjct: 726 RAVQEKEALVREKAALEVRLQAVERDR--QDLAEQLQGLSSAKELLESSLFEAQQQNSVI 783
Query: 326 SKIKVSLTTQLE---DTKRLADEEARERATLLGKFRN-LEHDLDNIREQVEE-EAEGKAD 490
K L Q++ K + E R L R+ E + D Q+ + E EGK
Sbjct: 784 EVTKGQLEVQIQTVTQAKEVIQGEVRCLKLELDTERSQAEQERDAAARQLAQAEQEGKTA 843
Query: 491 LQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEK 670
L++Q + E R K+E E +EL +A L+ E E ++ ++ A++
Sbjct: 844 LEQQKAAHEKEVNQLREKWEKERSWHQQELAKALESLEREKMELEMRLKEQQTEMEAIQA 903
Query: 671 TKQRLATEVE----DLQLEVDR 724
++ T+ E +QLE ++
Sbjct: 904 QREEERTQAESALCQMQLETEK 925
Score = 38.3 bits (85), Expect = 0.031
Identities = 53/230 (23%), Positives = 98/230 (42%)
Frame = +2
Query: 32 GEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKA 211
G + QL L AK ++ + +L EKA + V +L L + Q +
Sbjct: 240 GREPAQLLLLLAKTQELEKEAHERSQELIQLKSQGDLEKAELQDRVTELSALLTQSQKQN 299
Query: 212 DEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEA 391
++ + + L + L +++L+ E + S+ +Q K+ SL ++D ++ EE
Sbjct: 300 EDYEKMIKALRETVEILETNHTELMEH-EASLSRNAQEEKL--SLQQVIKDITQVMVEEG 356
Query: 392 RERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARS 571
A G +LE D + ++A+ L R + +A + + + G
Sbjct: 357 DNIAQGSGHENSLELDSSIFSQFDYQDADKALTLVRSVLTRRRQA-VQDLRQQLAGC--- 412
Query: 572 EELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
+EA LQ + + EE ++L Q++ L + LA + DLQ EVD
Sbjct: 413 ---QEAVNLLQQQHDQWEEEGKALRQRLQKLTGERDTLAGQTVDLQGEVD 459
Score = 37.1 bits (82), Expect = 0.071
Identities = 49/241 (20%), Positives = 102/241 (42%), Gaps = 5/241 (2%)
Frame = +2
Query: 2 NSAGRFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQ 181
+ A R ++ ++L+ L + + +A+ + + + L+ L+ + ++ +
Sbjct: 1806 DEAQRALAQRDQELEALQQEQQQAQGQEERVKEKADALQGALEQAHMTLKERHGELQDHK 1865
Query: 182 HQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLE 361
Q ++ + R + L+ L E+ + + L + Q ++ ++ T L+
Sbjct: 1866 EQARRLEEELAVEGRRVQALEEVLGDLRAESREQEKALLALQQQCAEQAQEHEVETRALQ 1925
Query: 362 DTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKAD-LQRQLSKANAEAQLWR 538
D+ A +ER + L + + R Q EE A +A+ LQ L KA+A Q +
Sbjct: 1926 DSWLQAQAVLKERDQ---ELEALRAESQSSRHQ-EEAARARAEALQEALGKAHAALQ-GK 1980
Query: 539 SKYESEGVARSEELEEAKRKLQARL----AEAEETIESLNQKVVALEKTKQRLATEVEDL 706
++ E S LE + LQA L A + + E+L + ++ R +V+ L
Sbjct: 1981 EQHLLEQAELSRSLEASTATLQASLDACQAHSRQLEEALRIQEGEIQDQDLRYQEDVQQL 2040
Query: 707 Q 709
Q
Sbjct: 2041 Q 2041
Score = 36.7 bits (81), Expect = 0.094
Identities = 37/205 (18%), Positives = 96/205 (46%), Gaps = 7/205 (3%)
Frame = +2
Query: 56 KLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLN 235
KL + E+ R + + R L+H E ++++++ + Q+ +++ +
Sbjct: 1502 KLTVQREQIR-ELEKDRETQRNVLEHQLLELEKKDQMIESQRGQVQDLKKQLVTLECLAL 1560
Query: 236 DLDAAKKKLSIENSDLLRQLE-EAESQVSQLSKIKVSLTTQLEDTKRLADE--EARERAT 406
+L+ K+ + L+++LE + E+Q L+ + + L + ++ + + + + +T
Sbjct: 1561 ELEENHHKMECQQK-LIKELEGQRETQRVALTHLTLDLEERSQELQAQSSQIHDLESHST 1619
Query: 407 LLGK-FRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSK---YESEGVARSE 574
+L + + + ++ + REQ+EE K L + L + + E L + + E + +++
Sbjct: 1620 VLARELQERDQEVKSQREQIEELQRQKEHLTQDLERRDQELMLQKERIQVLEDQRTRQTK 1679
Query: 575 ELEEAKRKLQARLAEAEETIESLNQ 649
LEE +++ L E + + Q
Sbjct: 1680 ILEEDLEQIKLSLRERGRELTTQRQ 1704
>AF049105-1|AAC07988.1| 2442|Homo sapiens centrosomal Nek2-associated
protein 1 protein.
Length = 2442
Score = 54.8 bits (126), Expect = 3e-07
Identities = 59/230 (25%), Positives = 108/230 (46%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD 214
+Q+ +L + E ++Q +E+ DL+ L EK+ E KQ N ++S+
Sbjct: 1264 DQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEG--KQ-----NSLESELM 1316
Query: 215 EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEAR 394
E + T+ L + ++ ++ EA+ + L K +LT Q+E + A EAR
Sbjct: 1317 ELHETMASLQSRLRRAELQRM-------EAQGERELLQAAKENLTAQVEHLQA-AVVEAR 1368
Query: 395 ERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSE 574
+A+ G LE DL R ++ + E +++ + +A A + K VA+ +
Sbjct: 1369 AQASAAGI---LEEDLRTARSALKLKNE---EVESERERAQALQEQGELK-----VAQGK 1417
Query: 575 ELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
L+E L LAE EE +E+L ++ LEK ++ +E L L++ +
Sbjct: 1418 ALQENLALLTQTLAEREEEVETLRGQIQELEKQREMQKAALELLSLDLKK 1467
Score = 53.2 bits (122), Expect = 1e-06
Identities = 59/237 (24%), Positives = 105/237 (44%), Gaps = 16/237 (6%)
Frame = +2
Query: 44 DQLNKLKAKAEKXRAQYFSEVNDLRAGLD--HLSNEKAAQEKI-----VKQLQHQLNEVQ 202
++L ++ E +++ SE+ LR L+ HL E QE+ + + + + E+
Sbjct: 522 ERLQEMLMGLEAKQSESLSELITLREALESSHLEGELLRQEQTEVTAALARAEQSIAELS 581
Query: 203 SKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKR--- 373
S + + DL AA KLS N L Q+ QL + S+ +++E ++
Sbjct: 582 SSENTLKTEVADLRAAAVKLSALNEALALDKVGLNQQLLQLEEENQSVCSRMEAAEQARN 641
Query: 374 -----LADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWR 538
LA+ E R A L K +LE L E E D+Q + K + +L
Sbjct: 642 ALQVDLAEAEKRREA-LWEKNTHLEAQLQKAEEAGAELQADLRDIQEE--KEEIQKKLSE 698
Query: 539 SKYESEGVARS-EELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDL 706
S+++ E E+L + ++ + LA A + E+L ++ ALE Q + + +DL
Sbjct: 699 SRHQQEAATTQLEQLHQEAKRQEEVLARAVQEKEALVREKAALEVRLQAVERDRQDL 755
Score = 52.4 bits (120), Expect = 2e-06
Identities = 46/207 (22%), Positives = 95/207 (45%), Gaps = 9/207 (4%)
Frame = +2
Query: 131 HLS-NEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAE 307
HL+ E+ ++++ L+ + +E S+ L + L E +++ L AE
Sbjct: 515 HLAVRERERLQEMLMGLEAKQSESLSELITLREALESSHLEGELLRQEQTEVTAALARAE 574
Query: 308 SQVSQLSKIKVSLTTQLEDTKRLA-------DEEARERATLLGKFRNLEHDLDNIREQVE 466
+++LS + +L T++ D + A + A ++ L + LE + ++ ++E
Sbjct: 575 QSIAELSSSENTLKTEVADLRAAAVKLSALNEALALDKVGLNQQLLQLEEENQSVCSRME 634
Query: 467 EEAEGKADLQRQLSKANAEAQ-LWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESL 643
+ + LQ L++A + LW E A+ ++ EEA +LQA L + +E E +
Sbjct: 635 AAEQARNALQVDLAEAEKRREALWEKNTHLE--AQLQKAEEAGAELQADLRDIQEEKEEI 692
Query: 644 NQKVVALEKTKQRLATEVEDLQLEVDR 724
+K+ ++ T++E L E R
Sbjct: 693 QKKLSESRHQQEAATTQLEQLHQEAKR 719
Score = 50.0 bits (114), Expect = 9e-06
Identities = 53/202 (26%), Positives = 87/202 (43%), Gaps = 9/202 (4%)
Frame = +2
Query: 146 KAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQL 325
+A QEK + EV+ +A E +R DL + LS L L EA+ Q S +
Sbjct: 726 RAVQEKEALVREKAALEVRLQAVERDR--QDLAEQLQGLSSAKELLESSLFEAQQQNSVI 783
Query: 326 SKIKVSLTTQLE---DTKRLADEEARERATLLGKFRN-LEHDLDNIREQVEE-EAEGKAD 490
K L Q++ K + E R L R+ E + D Q+ + E EGK
Sbjct: 784 EVTKGQLEVQIQTVTQAKEVIQGEVRCLKLELDTERSQAEQERDAAARQLAQAEQEGKTA 843
Query: 491 LQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEK 670
L++Q + E R K+E E +EL +A L+ E E ++ ++ A++
Sbjct: 844 LEQQKAAHEKEVNQLREKWEKERSWHQQELAKALESLEREKMELEMRLKEQQTEMEAIQA 903
Query: 671 TKQRLATEVE----DLQLEVDR 724
++ T+ E +QLE ++
Sbjct: 904 QREEERTQAESALCQMQLETEK 925
Score = 38.3 bits (85), Expect = 0.031
Identities = 53/230 (23%), Positives = 98/230 (42%)
Frame = +2
Query: 32 GEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKA 211
G + QL L AK ++ + +L EKA + V +L L + Q +
Sbjct: 240 GREPAQLLLLLAKTQELEKEAHERSQELIQLKSQGDLEKAELQDRVTELSALLTQSQKQN 299
Query: 212 DEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEA 391
++ + + L + L +++L+ E + S+ +Q K+ SL ++D ++ EE
Sbjct: 300 EDYEKMIKALRETVEILETNHTELMEH-EASLSRNAQEEKL--SLQQVIKDITQVMVEEG 356
Query: 392 RERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARS 571
A G +LE D + ++A+ L R + +A + + + G
Sbjct: 357 DNIAQGSGHENSLELDSSIFSQFDYQDADKALTLVRSVLTRRRQA-VQDLRQQLAGC--- 412
Query: 572 EELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
+EA LQ + + EE ++L Q++ L + LA + DLQ EVD
Sbjct: 413 ---QEAVNLLQQQHDQWEEEGKALRQRLQKLTGERDTLAGQTVDLQGEVD 459
Score = 37.1 bits (82), Expect = 0.071
Identities = 49/241 (20%), Positives = 102/241 (42%), Gaps = 5/241 (2%)
Frame = +2
Query: 2 NSAGRFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQ 181
+ A R ++ ++L+ L + + +A+ + + + L+ L+ + ++ +
Sbjct: 1806 DEAQRALAQRDQELEALQQEQQQAQGQEERVKEKADALQGALEQAHMTLKERHGELQDHK 1865
Query: 182 HQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLE 361
Q ++ + R + L+ L E+ + + L + Q ++ ++ T L+
Sbjct: 1866 EQARRLEEELAVEGRRVQALEEVLGDLRAESREQEKALLALQQQCAEQAQEHEVETRALQ 1925
Query: 362 DTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKAD-LQRQLSKANAEAQLWR 538
D+ A +ER + L + + R Q EE A +A+ LQ L KA+A Q +
Sbjct: 1926 DSWLQAQAVLKERDQ---ELEALRAESQSSRHQ-EEAARARAEALQEALGKAHAALQ-GK 1980
Query: 539 SKYESEGVARSEELEEAKRKLQARL----AEAEETIESLNQKVVALEKTKQRLATEVEDL 706
++ E S LE + LQA L A + + E+L + ++ R +V+ L
Sbjct: 1981 EQHLLEQAELSRSLEASTATLQASLDACQAHSRQLEEALRIQEGEIQDQDLRYQEDVQQL 2040
Query: 707 Q 709
Q
Sbjct: 2041 Q 2041
Score = 36.7 bits (81), Expect = 0.094
Identities = 37/205 (18%), Positives = 96/205 (46%), Gaps = 7/205 (3%)
Frame = +2
Query: 56 KLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLN 235
KL + E+ R + + R L+H E ++++++ + Q+ +++ +
Sbjct: 1502 KLTVQREQIR-ELEKDRETQRNVLEHQLLELEKKDQMIESQRGQVQDLKKQLVTLECLAL 1560
Query: 236 DLDAAKKKLSIENSDLLRQLE-EAESQVSQLSKIKVSLTTQLEDTKRLADE--EARERAT 406
+L+ K+ + L+++LE + E+Q L+ + + L + ++ + + + + +T
Sbjct: 1561 ELEENHHKMECQQK-LIKELEGQRETQRVALTHLTLDLEERSQELQAQSSQIHDLESHST 1619
Query: 407 LLGK-FRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSK---YESEGVARSE 574
+L + + + ++ + REQ+EE K L + L + + E L + + E + +++
Sbjct: 1620 VLARELQERDQEVKSQREQIEELQRQKEHLTQDLERRDQELMLQKERIQVLEDQRTRQTK 1679
Query: 575 ELEEAKRKLQARLAEAEETIESLNQ 649
LEE +++ L E + + Q
Sbjct: 1680 ILEEDLEQIKLSLRERGRELTTQRQ 1704
>AF022655-1|AAC06349.1| 2442|Homo sapiens cep250 centrosome associated
protein protein.
Length = 2442
Score = 54.8 bits (126), Expect = 3e-07
Identities = 59/230 (25%), Positives = 108/230 (46%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD 214
+Q+ +L + E ++Q +E+ DL+ L EK+ E KQ N ++S+
Sbjct: 1264 DQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEG--KQ-----NSLESELM 1316
Query: 215 EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEAR 394
E + T+ L + ++ ++ EA+ + L K +LT Q+E + A EAR
Sbjct: 1317 ELHETMASLQSRLRRAELQRM-------EAQGERELLQAAKENLTAQVEHLQA-AVVEAR 1368
Query: 395 ERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSE 574
+A+ G LE DL R ++ + E +++ + +A A + K VA+ +
Sbjct: 1369 AQASAAGI---LEEDLRTARSALKLKNE---EVESERERAQALQEQGELK-----VAQGK 1417
Query: 575 ELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
L+E L LAE EE +E+L ++ LEK ++ +E L L++ +
Sbjct: 1418 ALQENLALLTQTLAEREEEVETLRGQIQELEKQREMQKAALELLSLDLKK 1467
Score = 54.0 bits (124), Expect = 6e-07
Identities = 46/207 (22%), Positives = 96/207 (46%), Gaps = 9/207 (4%)
Frame = +2
Query: 131 HLS-NEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAE 307
HL+ E+ ++++ L+ + +E S+ L + + L E +++ L AE
Sbjct: 515 HLAVRERERLQEMLMGLEAKQSESLSELITLREALESIHLEGELLRQEQTEVTAALARAE 574
Query: 308 SQVSQLSKIKVSLTTQLEDTKRLA-------DEEARERATLLGKFRNLEHDLDNIREQVE 466
+++LS + +L T++ D + A + A ++ L + LE + ++ ++E
Sbjct: 575 QSIAELSSSENTLKTEVADLRAAAVKLSALNEALALDKVGLNQQLLQLEEENQSVCSRME 634
Query: 467 EEAEGKADLQRQLSKANAEAQ-LWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESL 643
+ + LQ L++A + LW E A+ ++ EEA +LQA L + +E E +
Sbjct: 635 AAEQARNALQVDLAEAEKRREALWEKNTHLE--AQLQKAEEAGAELQADLRDIQEEKEEI 692
Query: 644 NQKVVALEKTKQRLATEVEDLQLEVDR 724
+K+ ++ T++E L E R
Sbjct: 693 QKKLSESRHQQEAATTQLEQLHQEAKR 719
Score = 53.6 bits (123), Expect = 8e-07
Identities = 59/241 (24%), Positives = 107/241 (44%), Gaps = 16/241 (6%)
Frame = +2
Query: 44 DQLNKLKAKAEKXRAQYFSEVNDLRAGLD--HLSNEKAAQEKI-----VKQLQHQLNEVQ 202
++L ++ E +++ SE+ LR L+ HL E QE+ + + + + E+
Sbjct: 522 ERLQEMLMGLEAKQSESLSELITLREALESIHLEGELLRQEQTEVTAALARAEQSIAELS 581
Query: 203 SKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKR--- 373
S + + DL AA KLS N L Q+ QL + S+ +++E ++
Sbjct: 582 SSENTLKTEVADLRAAAVKLSALNEALALDKVGLNQQLLQLEEENQSVCSRMEAAEQARN 641
Query: 374 -----LADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWR 538
LA+ E R A L K +LE L E E D+Q + K + +L
Sbjct: 642 ALQVDLAEAEKRREA-LWEKNTHLEAQLQKAEEAGAELQADLRDIQEE--KEEIQKKLSE 698
Query: 539 SKYESEGVARS-EELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLE 715
S+++ E E+L + ++ + LA A + E+L ++ ALE Q + + +DL +
Sbjct: 699 SRHQQEAATTQLEQLHQEAKRQEEVLARAVQEKEALVREKAALEVRLQAVERDRQDLAAQ 758
Query: 716 V 718
+
Sbjct: 759 L 759
Score = 50.8 bits (116), Expect = 5e-06
Identities = 53/202 (26%), Positives = 89/202 (44%), Gaps = 9/202 (4%)
Frame = +2
Query: 146 KAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQL 325
+A QEK + EV+ +A E +R DL A + LS L L EA+ Q S +
Sbjct: 726 RAVQEKEALVREKAALEVRLQAVERDR--QDLAAQLQGLSSAKELLESSLFEAQQQNSVI 783
Query: 326 SKIKVSLTTQLE---DTKRLADEEARERATLLGKFRN-LEHDLDNIREQVEE-EAEGKAD 490
+ + L Q++ K + E R L R+ E + D Q+ + E EGK
Sbjct: 784 DEPQGQLEVQIQTVTQAKEVIQGEVRCLKLELDTERSQAEQERDAAARQLAQAEQEGKTA 843
Query: 491 LQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEK 670
L++Q + E R K+E E +EL +A L+ E E ++ ++ A++
Sbjct: 844 LEQQKAAHEKEVNQLREKWEKERSWHQQELAKALESLEREKMELEMRLKEQQTEMEAIQA 903
Query: 671 TKQRLATEVE----DLQLEVDR 724
++ T+ E +QLE ++
Sbjct: 904 QREEERTQAESALCQMQLETEK 925
Score = 37.1 bits (82), Expect = 0.071
Identities = 49/241 (20%), Positives = 102/241 (42%), Gaps = 5/241 (2%)
Frame = +2
Query: 2 NSAGRFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQ 181
+ A R ++ ++L+ L + + +A+ + + + L+ L+ + ++ +
Sbjct: 1806 DEAQRALAQRDQELEALQQEQQQAQGQEERVKEKADALQGALEQAHMTLKERHGELQDHK 1865
Query: 182 HQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLE 361
Q ++ + R + L+ L E+ + + L + Q ++ ++ T L+
Sbjct: 1866 EQARRLEEELAVEGRRVQALEEVLGDLRAESREQEKALLALQQQCAEQAQEHEVETRALQ 1925
Query: 362 DTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKAD-LQRQLSKANAEAQLWR 538
D+ A +ER + L + + R Q EE A +A+ LQ L KA+A Q +
Sbjct: 1926 DSWLQAQAVLKERDQ---ELEALRAESQSSRHQ-EEAARARAEALQEALGKAHAALQ-GK 1980
Query: 539 SKYESEGVARSEELEEAKRKLQARL----AEAEETIESLNQKVVALEKTKQRLATEVEDL 706
++ E S LE + LQA L A + + E+L + ++ R +V+ L
Sbjct: 1981 EQHLLEQAELSRSLEASTATLQASLDACQAHSRQLEEALRIQEGEIQDQDLRYQEDVQQL 2040
Query: 707 Q 709
Q
Sbjct: 2041 Q 2041
Score = 36.3 bits (80), Expect = 0.12
Identities = 52/230 (22%), Positives = 98/230 (42%)
Frame = +2
Query: 32 GEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKA 211
G + QL L AK ++ + +L EKA + V +L L + Q +
Sbjct: 240 GREPAQLLLLLAKTQELEKEAHERSQELIQLKSQGDLEKAELQDRVTELSALLTQSQKQN 299
Query: 212 DEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEA 391
++ + + L + L +++L+ E + S+ +Q K+ SL ++D ++ EE
Sbjct: 300 EDYEKMIKALRETVEILETNHTELMEH-EASLSRNAQEEKL--SLQQVIKDITQVMVEEG 356
Query: 392 RERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARS 571
A G +LE + + ++A+ L R + +A + + + G
Sbjct: 357 DNIAQGSGLENSLELESSIFSQFDYQDADKALTLVRSVLTRRRQA-VQDLRQQLAGC--- 412
Query: 572 EELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
+EA LQ + + EE ++L Q++ L + LA + DLQ EVD
Sbjct: 413 ---QEAVNLLQQQHDQWEEEGKALRQRLQKLTGERDTLAGQTVDLQGEVD 459
Score = 36.3 bits (80), Expect = 0.12
Identities = 32/182 (17%), Positives = 87/182 (47%), Gaps = 7/182 (3%)
Frame = +2
Query: 125 LDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLE-E 301
L+H E ++++++ + Q+ +++ + +L+ K+ + L+++LE +
Sbjct: 1524 LEHQLLELEKKDQMIESQRGQVQDLKKQLVTLECLALELEENHHKMECQQK-LIKELEGQ 1582
Query: 302 AESQVSQLSKIKVSLTTQLEDTKRLADE--EARERATLLGK-FRNLEHDLDNIREQVEEE 472
E+Q L+ + + L + ++ + + + + +T+L + + + ++ + REQ+EE
Sbjct: 1583 RETQRVALTHLTLDLEERSQELQAQSSQIHDLESHSTVLARELQERDQEVKSQREQIEEL 1642
Query: 473 AEGKADLQRQLSKANAEAQLWRSK---YESEGVARSEELEEAKRKLQARLAEAEETIESL 643
K L + L + + E L + + E + +++ LEE +++ L E + +
Sbjct: 1643 QRQKEHLTQDLERRDQELMLQKERIQVLEDQRTRQTKILEEDLEQIKLSLRERGRELTTQ 1702
Query: 644 NQ 649
Q
Sbjct: 1703 RQ 1704
>M63618-1|AAA35606.1| 2095|Homo sapiens bullous pemphigoid antigen
protein.
Length = 2095
Score = 54.0 bits (124), Expect = 6e-07
Identities = 63/249 (25%), Positives = 108/249 (43%), Gaps = 19/249 (7%)
Frame = +2
Query: 26 DMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQS 205
++ +Q+D+L KAE+ + E+N L+ EK + E+ + L+ +L+E +
Sbjct: 809 ELKQQVDELTAANRKAEQDMRELTYELNALQL-------EKTSSEEKARLLKDKLDETNN 861
Query: 206 KADEANRTLNDLDAAKKKLSIENSDLLRQL-------EEAESQVSQLSKIKVSLTTQLED 364
L D A+K S + +L RQL EEA + S L KIK + +LE
Sbjct: 862 TLRCLKLELERKDQAEKGYSQQLRELGRQLNQTTGKAEEAMQEASDLKKIKRNYQLELES 921
Query: 365 -------TKRLADEEARERATLLGKFRNLEHDLDNIREQVEEE----AEGKAD-LQRQLS 508
+R D R A ++L + + R++ E E + K+D L+ Q
Sbjct: 922 LNHEKGKLQREVDRITRAHAVAEKNIQHLNSQIHSFRDEKELERLQICQRKSDHLKEQFE 981
Query: 509 KANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLA 688
K++ E L K E E + + L E K ++ +E L ++ + QR+
Sbjct: 982 KSH-EQLLQNIKAEKENNDKIQRLNEELEKSNECAEMLKQKVEELTRQNNETKLMMQRIQ 1040
Query: 689 TEVEDLQLE 715
E E++ LE
Sbjct: 1041 AESENIVLE 1049
Score = 42.7 bits (96), Expect = 0.001
Identities = 38/198 (19%), Positives = 99/198 (50%), Gaps = 5/198 (2%)
Frame = +2
Query: 23 SDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQ 202
S + ++ +L ++ A+ +K +++ E+ +R + NE Q++ V+ + Q +
Sbjct: 580 SKLTGKISELERMVAELKKQKSRVEEELPKVREAAE---NELRKQQRNVEDISLQKIRAE 636
Query: 203 SKADEANRTLNDLDAAKKKLSIENSDLLRQLE-EAESQVSQLSKIKVSLTTQLED---TK 370
S+A + R L + +K+ + + +RQL EAE++ + + + ++ QLE+ T+
Sbjct: 637 SEAKQYRRELETI-VREKEAAERELERVRQLTIEAEAKRAAVEENLLNFRNQLEENTFTR 695
Query: 371 RLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYE 550
R ++ + + L +LE + + E++ + + + +L + + + + + E
Sbjct: 696 RTLEDHLKRKDLSL---NDLEQQKNKLMEELRRKRDNEEELLKLIKQMEKDLAFQKQVAE 752
Query: 551 SEGVARSEELE-EAKRKL 601
+ + +++E EA+RK+
Sbjct: 753 KQ-LKEKQKIELEARRKI 769
>L11690-1|AAA52288.1| 2649|Homo sapiens bullous pemphigoid antigen
protein.
Length = 2649
Score = 54.0 bits (124), Expect = 6e-07
Identities = 63/249 (25%), Positives = 108/249 (43%), Gaps = 19/249 (7%)
Frame = +2
Query: 26 DMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQS 205
++ +Q+D+L KAE+ + E+N L+ EK + E+ + L+ +L+E +
Sbjct: 1363 ELKQQVDELTAANRKAEQDMRELTYELNALQL-------EKTSSEEKARLLKDKLDETNN 1415
Query: 206 KADEANRTLNDLDAAKKKLSIENSDLLRQL-------EEAESQVSQLSKIKVSLTTQLED 364
L D A+K S + +L RQL EEA + S L KIK + +LE
Sbjct: 1416 TLRCLKLELERKDQAEKGYSQQLRELGRQLNQTTGKAEEAMQEASDLKKIKRNYQLELES 1475
Query: 365 -------TKRLADEEARERATLLGKFRNLEHDLDNIREQVEEE----AEGKAD-LQRQLS 508
+R D R A ++L + + R++ E E + K+D L+ Q
Sbjct: 1476 LNHEKGKLQREVDRITRAHAVAEKNIQHLNSQIHSFRDEKELERLQICQRKSDHLKEQFE 1535
Query: 509 KANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLA 688
K++ E L K E E + + L E K ++ +E L ++ + QR+
Sbjct: 1536 KSH-EQLLQNIKAEKENNDKIQRLNEELEKSNECAEMLKQKVEELTRQNNETKLMMQRIQ 1594
Query: 689 TEVEDLQLE 715
E E++ LE
Sbjct: 1595 AESENIVLE 1603
Score = 42.7 bits (96), Expect = 0.001
Identities = 38/198 (19%), Positives = 99/198 (50%), Gaps = 5/198 (2%)
Frame = +2
Query: 23 SDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQ 202
S + ++ +L ++ A+ +K +++ E+ +R + NE Q++ V+ + Q +
Sbjct: 1134 SKLTGKISELERMVAELKKQKSRVEEELPKVREAAE---NELRKQQRNVEDISLQKIRAE 1190
Query: 203 SKADEANRTLNDLDAAKKKLSIENSDLLRQLE-EAESQVSQLSKIKVSLTTQLED---TK 370
S+A + R L + +K+ + + +RQL EAE++ + + + ++ QLE+ T+
Sbjct: 1191 SEAKQYRRELETI-VREKEAAERELERVRQLTIEAEAKRAAVEENLLNFRNQLEENTFTR 1249
Query: 371 RLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYE 550
R ++ + + L +LE + + E++ + + + +L + + + + + E
Sbjct: 1250 RTLEDHLKRKDLSL---NDLEQQKNKLMEELRRKRDNEEELLKLIKQMEKDLAFQKQVAE 1306
Query: 551 SEGVARSEELE-EAKRKL 601
+ + +++E EA+RK+
Sbjct: 1307 KQ-LKEKQKIELEARRKI 1323
>BC113114-1|AAI13115.1| 1354|Homo sapiens Rho-associated, coiled-coil
containing protein kinase 1 protein.
Length = 1354
Score = 54.0 bits (124), Expect = 6e-07
Identities = 67/256 (26%), Positives = 112/256 (43%), Gaps = 17/256 (6%)
Frame = +2
Query: 5 SAGRFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQ--- 175
S + + + EQL +LK + E+ +++ + LD N++ E V Q
Sbjct: 427 SLQKTIYKLEEQLHNEMQLKDEMEQKCRTSNIKLDKIMKELDEEGNQRRNLESTVSQIEK 486
Query: 176 ----LQHQLNEVQSKADEANRTLNDLDAAKKKLSIEN--SDLLRQLEEAE--SQVSQLSK 331
LQH++NE Q KA++ N +K+ ++EN S L QLE+ + SQ SQL+
Sbjct: 487 EKMLLQHRINEYQRKAEQEN---------EKRRNVENEVSTLKNQLEDLKKVSQNSQLAN 537
Query: 332 IKVS-LTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLS 508
K+S L QLE+ L E+ L + + + E E L+ S
Sbjct: 538 EKLSQLQKQLEEANDLLRTESDTAVRLRKSHTEMSKSISQLESLNRELQERNRILENSKS 597
Query: 509 KANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLN---QKVVALEKTKQ 679
+ + + ++ E+E R + E LQAR+ +E ++ L +KV K Q
Sbjct: 598 QTDKDYYQLQAILEAERRDRGHD-SEMIGDLQARITSLQEEVKHLKHNLEKVEGERKEAQ 656
Query: 680 RLA--TEVEDLQLEVD 721
+ +E E LE+D
Sbjct: 657 DMLNHSEKEKNNLEID 672
Score = 48.0 bits (109), Expect = 4e-05
Identities = 44/173 (25%), Positives = 81/173 (46%), Gaps = 3/173 (1%)
Frame = +2
Query: 134 LSNEKAAQEKI---VKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEA 304
L E+ A+EK V Q++ Q + + ++ + L L K+++ E +L QLE+
Sbjct: 720 LKEEREAREKAENRVVQIEKQCSMLDVDLKQSQQKLEHLTGNKERMEDEVKNLTLQLEQE 779
Query: 305 ESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGK 484
++ L + + ++ K L + +E TLL R LE +L + +Q
Sbjct: 780 SNKRLLLQNELKTQAFEADNLKGLEKQMKQEINTLLEAKRLLEFELAQLTKQYRGNEGQM 839
Query: 485 ADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESL 643
+LQ QL AE Q + + Y+++ EE+EE R+ ++ E + E+L
Sbjct: 840 RELQDQL---EAE-QYFSTLYKTQVKELKEEIEEKNRENLKKIQELQNEKETL 888
>BC034046-1|AAH34046.1| 1202|Homo sapiens protein tyrosine
phosphatase, receptor type, f polypeptide (PTPRF),
interacting protein.
Length = 1202
Score = 54.0 bits (124), Expect = 6e-07
Identities = 58/248 (23%), Positives = 106/248 (42%), Gaps = 9/248 (3%)
Frame = +2
Query: 5 SAGRFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQH 184
S V+++ E LD K K+E+ + +V + A + + EK Q
Sbjct: 275 SLSSHVTELEEDLDTARKDLIKSEEMNTKLQRDVREAMAQKEDMEERITTLEKRYLAAQR 334
Query: 185 QLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQ-LSKIKVSLTTQLE 361
+ V D+ + + D+ ++ +N L +LE AE ++ Q L K + + E
Sbjct: 335 EATSVHDLNDKLENEIANKDSMHRQTEDKNRQLQERLELAEQKLQQTLRKAETLPEVEAE 394
Query: 362 DTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRS 541
+R+A E + N+E L + Q+EE+ + + RQ K N E +
Sbjct: 395 LAQRVAALSKAEE-----RHGNIEERLRQMEAQLEEKNQ-ELQRARQREKMNEE----HN 444
Query: 542 KYESEGVAR--SEELEEAKRKLQARLAEAEET------IESLNQKVVALEKTKQRLATEV 697
K S+ V + SE E + L+ R+A E+ +ES +++ + K +L +
Sbjct: 445 KRLSDTVDKLLSESNERLQLHLKERMAALEDKNSLLREVESAKKQLEGTQHDKDQLVLNI 504
Query: 698 EDLQLEVD 721
E L+ E+D
Sbjct: 505 EALRAELD 512
Score = 48.0 bits (109), Expect = 4e-05
Identities = 45/195 (23%), Positives = 89/195 (45%)
Frame = +2
Query: 98 SEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENS 277
++V +L+ + S E++ ++ + L + E++ D A + L + KL +
Sbjct: 250 AKVIELQEIISKQSREQSQMKERLASLSSHVTELEEDLDTARKDLIKSEEMNTKLQRDVR 309
Query: 278 DLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIRE 457
+ + Q E+ E +++ L K ++ + L D+ E A R E ++E
Sbjct: 310 EAMAQKEDMEERITTLEKRYLAAQREATSVHDLNDKLENEIANKDSMHRQTEDKNRQLQE 369
Query: 458 QVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIE 637
++E AE K LQ+ L KA ++ ++ VA + EE ++ RL + E +E
Sbjct: 370 RLEL-AEQK--LQQTLRKAETLPEVEAEL--AQRVAALSKAEERHGNIEERLRQMEAQLE 424
Query: 638 SLNQKVVALEKTKQR 682
NQ+ L++ +QR
Sbjct: 425 EKNQE---LQRARQR 436
Score = 33.9 bits (74), Expect = 0.66
Identities = 54/248 (21%), Positives = 108/248 (43%), Gaps = 24/248 (9%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLS-----NEKAAQEKIVKQLQHQLNEV 199
++L+ + + E+ A+ +E N+ R L+HL +E++ + +VK+ V
Sbjct: 95 KELNVCREQLLEREEEIAELKAERNNTRLLLEHLECLVSRHERSLRMTVVKRQAQSPAGV 154
Query: 200 QSKAD---------EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTT 352
S+ + E ++ L++ + ++++E LL + A + + K + +
Sbjct: 155 SSEVEVLKALKSLFEHHKALDEKVRERLRVALERCSLLEEELGATHKELMILKEQNNQKK 214
Query: 353 QLEDTKRLADEEARERATLLGKFRN---LEHDLDNIRE-QVEEEAEGKADLQRQLSKANA 520
L D + E + GK + L H+ D + +++E ++ Q Q+ + A
Sbjct: 215 TLTDGVLDINHEQENTPSTSGKRSSDGSLSHEEDLAKVIELQEIISKQSREQSQMKERLA 274
Query: 521 EAQLWRSKYESE-GVARSEEL--EEAKRKLQARLAEAEETIESLNQKVVALEK---TKQR 682
++ E + AR + + EE KLQ + EA E + +++ LEK QR
Sbjct: 275 SLSSHVTELEEDLDTARKDLIKSEEMNTKLQRDVREAMAQKEDMEERITTLEKRYLAAQR 334
Query: 683 LATEVEDL 706
AT V DL
Sbjct: 335 EATSVHDL 342
Score = 33.9 bits (74), Expect = 0.66
Identities = 38/170 (22%), Positives = 70/170 (41%), Gaps = 3/170 (1%)
Frame = +2
Query: 29 MGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDH---LSNEKAAQEKIVKQLQHQLNEV 199
+ +++ L LK+ E +A LR L+ L E A K + L+ Q N+
Sbjct: 154 VSSEVEVLKALKSLFEHHKALDEKVRERLRVALERCSLLEEELGATHKELMILKEQNNQK 213
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
++ D LD ++ + ++ R + + S L+K+ + L + R
Sbjct: 214 KTLTDGV------LDINHEQENTPSTSGKRSSDGSLSHEEDLAKV-IELQEIISKQSREQ 266
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQ 529
+ A+L LE DLD R+ + + E LQR + +A A+ +
Sbjct: 267 SQMKERLASLSSHVTELEEDLDTARKDLIKSEEMNTKLQRDVREAMAQKE 316
>AL096710-6|CAI22047.1| 2649|Homo sapiens dystonin protein.
Length = 2649
Score = 54.0 bits (124), Expect = 6e-07
Identities = 63/249 (25%), Positives = 108/249 (43%), Gaps = 19/249 (7%)
Frame = +2
Query: 26 DMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQS 205
++ +Q+D+L KAE+ + E+N L+ EK + E+ + L+ +L+E +
Sbjct: 1363 ELKQQVDELTAANRKAEQDMRELTYELNALQL-------EKTSSEEKARLLKDKLDETNN 1415
Query: 206 KADEANRTLNDLDAAKKKLSIENSDLLRQL-------EEAESQVSQLSKIKVSLTTQLED 364
L D A+K S + +L RQL EEA + S L KIK + +LE
Sbjct: 1416 TLRCLKLELERKDQAEKGYSQQLRELGRQLNQTTGKAEEAMQEASDLKKIKRNYQLELES 1475
Query: 365 -------TKRLADEEARERATLLGKFRNLEHDLDNIREQVEEE----AEGKAD-LQRQLS 508
+R D R A ++L + + R++ E E + K+D L+ Q
Sbjct: 1476 LNHEKGKLQREVDRITRAHAVAEKNIQHLNSQIHSFRDEKELERLQICQRKSDHLKEQFE 1535
Query: 509 KANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLA 688
K++ E L K E E + + L E K ++ +E L ++ + QR+
Sbjct: 1536 KSH-EQLLQNIKAEKENNDKIQRLNEELEKSNECAEMLKQKVEELTRQNNETKLMMQRIQ 1594
Query: 689 TEVEDLQLE 715
E E++ LE
Sbjct: 1595 AESENIVLE 1603
Score = 42.7 bits (96), Expect = 0.001
Identities = 38/198 (19%), Positives = 99/198 (50%), Gaps = 5/198 (2%)
Frame = +2
Query: 23 SDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQ 202
S + ++ +L ++ A+ +K +++ E+ +R + NE Q++ V+ + Q +
Sbjct: 1134 SKLTGKISELERMVAELKKQKSRVEEELPKVREAAE---NELRKQQRNVEDISLQKIRAE 1190
Query: 203 SKADEANRTLNDLDAAKKKLSIENSDLLRQLE-EAESQVSQLSKIKVSLTTQLED---TK 370
S+A + R L + +K+ + + +RQL EAE++ + + + ++ QLE+ T+
Sbjct: 1191 SEAKQYRRELETI-VREKEAAERELERVRQLTIEAEAKRAAVEENLLNFRNQLEENTFTR 1249
Query: 371 RLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYE 550
R ++ + + L +LE + + E++ + + + +L + + + + + E
Sbjct: 1250 RTLEDHLKRKDLSL---NDLEQQKNKLMEELRRKRDNEEELLKLIKQMEKDLAFQKQVAE 1306
Query: 551 SEGVARSEELE-EAKRKL 601
+ + +++E EA+RK+
Sbjct: 1307 KQ-LKEKQKIELEARRKI 1323
>U22816-1|AAC50173.1| 1202|Homo sapiens LAR-interacting protein 1b
protein.
Length = 1202
Score = 53.6 bits (123), Expect = 8e-07
Identities = 58/248 (23%), Positives = 106/248 (42%), Gaps = 9/248 (3%)
Frame = +2
Query: 5 SAGRFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQH 184
S V+++ E LD K K+E+ + +V + A + + EK Q
Sbjct: 275 SLSSHVTELEEDLDTARKDLIKSEEMNTKLQRDVREAMAQKEDMEERITTLEKRYLAAQR 334
Query: 185 QLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQ-LSKIKVSLTTQLE 361
+ V D+ + + D+ ++ +N L +LE AE ++ Q L K + + E
Sbjct: 335 EATSVHDLNDKLENEIANKDSMHRQTEDKNRQLQERLELAEQKLQQTLRKAETLPEVEAE 394
Query: 362 DTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRS 541
+R+A E + N+E L + Q+EE+ + + RQ K N E +
Sbjct: 395 LAQRVAALSKAEE-----RHGNIEERLRQMEAQLEEKNQ-ELQRARQREKMNEE----HN 444
Query: 542 KYESEGVAR--SEELEEAKRKLQARLAEAEET------IESLNQKVVALEKTKQRLATEV 697
K S+ V + SE E + L+ R+A E+ +ES +++ + K +L +
Sbjct: 445 KRLSDTVDKLLSESNERLQLHLKERMAALEDKNSLLREVESAKKQLEETQHDKDQLVLNI 504
Query: 698 EDLQLEVD 721
E L+ E+D
Sbjct: 505 EALRAELD 512
Score = 48.0 bits (109), Expect = 4e-05
Identities = 45/195 (23%), Positives = 89/195 (45%)
Frame = +2
Query: 98 SEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENS 277
++V +L+ + S E++ ++ + L + E++ D A + L + KL +
Sbjct: 250 AKVIELQEIISKQSREQSQMKERLASLSSHVTELEEDLDTARKDLIKSEEMNTKLQRDVR 309
Query: 278 DLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIRE 457
+ + Q E+ E +++ L K ++ + L D+ E A R E ++E
Sbjct: 310 EAMAQKEDMEERITTLEKRYLAAQREATSVHDLNDKLENEIANKDSMHRQTEDKNRQLQE 369
Query: 458 QVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIE 637
++E AE K LQ+ L KA ++ ++ VA + EE ++ RL + E +E
Sbjct: 370 RLEL-AEQK--LQQTLRKAETLPEVEAEL--AQRVAALSKAEERHGNIEERLRQMEAQLE 424
Query: 638 SLNQKVVALEKTKQR 682
NQ+ L++ +QR
Sbjct: 425 EKNQE---LQRARQR 436
Score = 33.9 bits (74), Expect = 0.66
Identities = 54/248 (21%), Positives = 108/248 (43%), Gaps = 24/248 (9%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLS-----NEKAAQEKIVKQLQHQLNEV 199
++L+ + + E+ A+ +E N+ R L+HL +E++ + +VK+ V
Sbjct: 95 KELNVCREQLLEREEEIAELKAERNNTRLLLEHLECLVSRHERSLRMTVVKRQAQSPAGV 154
Query: 200 QSKAD---------EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTT 352
S+ + E ++ L++ + ++++E LL + A + + K + +
Sbjct: 155 SSEVEVLKALKSLFEHHKALDEKVRERLRVALERCSLLEEELGATHKELMILKEQNNQKK 214
Query: 353 QLEDTKRLADEEARERATLLGKFRN---LEHDLDNIRE-QVEEEAEGKADLQRQLSKANA 520
L D + E + GK + L H+ D + +++E ++ Q Q+ + A
Sbjct: 215 TLTDGVLDINHEQENTPSTSGKRSSDGSLSHEEDLAKVIELQEIISKQSREQSQMKERLA 274
Query: 521 EAQLWRSKYESE-GVARSEEL--EEAKRKLQARLAEAEETIESLNQKVVALEK---TKQR 682
++ E + AR + + EE KLQ + EA E + +++ LEK QR
Sbjct: 275 SLSSHVTELEEDLDTARKDLIKSEEMNTKLQRDVREAMAQKEDMEERITTLEKRYLAAQR 334
Query: 683 LATEVEDL 706
AT V DL
Sbjct: 335 EATSVHDL 342
Score = 33.9 bits (74), Expect = 0.66
Identities = 38/170 (22%), Positives = 70/170 (41%), Gaps = 3/170 (1%)
Frame = +2
Query: 29 MGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDH---LSNEKAAQEKIVKQLQHQLNEV 199
+ +++ L LK+ E +A LR L+ L E A K + L+ Q N+
Sbjct: 154 VSSEVEVLKALKSLFEHHKALDEKVRERLRVALERCSLLEEELGATHKELMILKEQNNQK 213
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
++ D LD ++ + ++ R + + S L+K+ + L + R
Sbjct: 214 KTLTDGV------LDINHEQENTPSTSGKRSSDGSLSHEEDLAKV-IELQEIISKQSREQ 266
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQ 529
+ A+L LE DLD R+ + + E LQR + +A A+ +
Sbjct: 267 SQMKERLASLSSHVTELEEDLDTARKDLIKSEEMNTKLQRDVREAMAQKE 316
>U22815-1|AAC50172.1| 1185|Homo sapiens LAR-interacting protein 1a
protein.
Length = 1185
Score = 53.6 bits (123), Expect = 8e-07
Identities = 58/248 (23%), Positives = 106/248 (42%), Gaps = 9/248 (3%)
Frame = +2
Query: 5 SAGRFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQH 184
S V+++ E LD K K+E+ + +V + A + + EK Q
Sbjct: 275 SLSSHVTELEEDLDTARKDLIKSEEMNTKLQRDVREAMAQKEDMEERITTLEKRYLAAQR 334
Query: 185 QLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQ-LSKIKVSLTTQLE 361
+ V D+ + + D+ ++ +N L +LE AE ++ Q L K + + E
Sbjct: 335 EATSVHDLNDKLENEIANKDSMHRQTEDKNRQLQERLELAEQKLQQTLRKAETLPEVEAE 394
Query: 362 DTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRS 541
+R+A E + N+E L + Q+EE+ + + RQ K N E +
Sbjct: 395 LAQRVAALSKAEE-----RHGNIEERLRQMEAQLEEKNQ-ELQRARQREKMNEE----HN 444
Query: 542 KYESEGVAR--SEELEEAKRKLQARLAEAEET------IESLNQKVVALEKTKQRLATEV 697
K S+ V + SE E + L+ R+A E+ +ES +++ + K +L +
Sbjct: 445 KRLSDTVDKLLSESNERLQLHLKERMAALEDKNSLLREVESAKKQLEETQHDKDQLVLNI 504
Query: 698 EDLQLEVD 721
E L+ E+D
Sbjct: 505 EALRAELD 512
Score = 48.0 bits (109), Expect = 4e-05
Identities = 45/195 (23%), Positives = 89/195 (45%)
Frame = +2
Query: 98 SEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENS 277
++V +L+ + S E++ ++ + L + E++ D A + L + KL +
Sbjct: 250 AKVIELQEIISKQSREQSQMKERLASLSSHVTELEEDLDTARKDLIKSEEMNTKLQRDVR 309
Query: 278 DLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIRE 457
+ + Q E+ E +++ L K ++ + L D+ E A R E ++E
Sbjct: 310 EAMAQKEDMEERITTLEKRYLAAQREATSVHDLNDKLENEIANKDSMHRQTEDKNRQLQE 369
Query: 458 QVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIE 637
++E AE K LQ+ L KA ++ ++ VA + EE ++ RL + E +E
Sbjct: 370 RLEL-AEQK--LQQTLRKAETLPEVEAEL--AQRVAALSKAEERHGNIEERLRQMEAQLE 424
Query: 638 SLNQKVVALEKTKQR 682
NQ+ L++ +QR
Sbjct: 425 EKNQE---LQRARQR 436
Score = 33.9 bits (74), Expect = 0.66
Identities = 54/248 (21%), Positives = 108/248 (43%), Gaps = 24/248 (9%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLS-----NEKAAQEKIVKQLQHQLNEV 199
++L+ + + E+ A+ +E N+ R L+HL +E++ + +VK+ V
Sbjct: 95 KELNVCREQLLEREEEIAELKAERNNTRLLLEHLECLVSRHERSLRMTVVKRQAQSPAGV 154
Query: 200 QSKAD---------EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTT 352
S+ + E ++ L++ + ++++E LL + A + + K + +
Sbjct: 155 SSEVEVLKALKSLFEHHKALDEKVRERLRVALERCSLLEEELGATHKELMILKEQNNQKK 214
Query: 353 QLEDTKRLADEEARERATLLGKFRN---LEHDLDNIRE-QVEEEAEGKADLQRQLSKANA 520
L D + E + GK + L H+ D + +++E ++ Q Q+ + A
Sbjct: 215 TLTDGVLDINHEQENTPSTSGKRSSDGSLSHEEDLAKVIELQEIISKQSREQSQMKERLA 274
Query: 521 EAQLWRSKYESE-GVARSEEL--EEAKRKLQARLAEAEETIESLNQKVVALEK---TKQR 682
++ E + AR + + EE KLQ + EA E + +++ LEK QR
Sbjct: 275 SLSSHVTELEEDLDTARKDLIKSEEMNTKLQRDVREAMAQKEDMEERITTLEKRYLAAQR 334
Query: 683 LATEVEDL 706
AT V DL
Sbjct: 335 EATSVHDL 342
Score = 33.9 bits (74), Expect = 0.66
Identities = 38/170 (22%), Positives = 70/170 (41%), Gaps = 3/170 (1%)
Frame = +2
Query: 29 MGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDH---LSNEKAAQEKIVKQLQHQLNEV 199
+ +++ L LK+ E +A LR L+ L E A K + L+ Q N+
Sbjct: 154 VSSEVEVLKALKSLFEHHKALDEKVRERLRVALERCSLLEEELGATHKELMILKEQNNQK 213
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLA 379
++ D LD ++ + ++ R + + S L+K+ + L + R
Sbjct: 214 KTLTDGV------LDINHEQENTPSTSGKRSSDGSLSHEEDLAKV-IELQEIISKQSREQ 266
Query: 380 DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQ 529
+ A+L LE DLD R+ + + E LQR + +A A+ +
Sbjct: 267 SQMKERLASLSSHVTELEEDLDTARKDLIKSEEMNTKLQRDVREAMAQKE 316
>DQ355971-1|ABC67469.1| 1711|Homo sapiens CDC42 binding protein
kinase beta (DMPK-like) protein.
Length = 1711
Score = 53.6 bits (123), Expect = 8e-07
Identities = 54/207 (26%), Positives = 108/207 (52%), Gaps = 3/207 (1%)
Frame = +2
Query: 110 DLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLR 289
D++ L+H S + A E+ +++L+ + E+ K E+ +T+ L + + LS N D +
Sbjct: 429 DVQRDLEH-SLQMEAYERRIRRLEQEKLELSRKLQESTQTVQSLHGSSRALSNSNRD--K 485
Query: 290 QLEEAESQVSQL-SKIKVS--LTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQ 460
++++ ++ +L +KI S L QLEDT L E RE +T + R LE +R++
Sbjct: 486 EIKKLNEEIERLKNKIADSNRLERQLEDTVALRQE--REDSTQ--RLRGLEKQHRVVRQE 541
Query: 461 VEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIES 640
EE L +QL +A+ + ++++EL++A ++ + L E E
Sbjct: 542 KEE-------LHKQLVEASERLK-----------SQAKELKDAHQQRKLALQEFSE---- 579
Query: 641 LNQKVVALEKTKQRLATEVEDLQLEVD 721
LN+++ L KQ+++ ++ D + E++
Sbjct: 580 LNERMAELRAQKQKVSRQLRDKEEEME 606
Score = 32.7 bits (71), Expect = 1.5
Identities = 42/217 (19%), Positives = 93/217 (42%), Gaps = 10/217 (4%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLN--EVQSK 208
+++D + + +AEK R + ++++D A + E KQ++ +L +V+
Sbjct: 610 QKVDAMRQEMRRAEKLRKELEAQLDDAVAEASKERKLREHSENFCKQMESELEALKVKQG 669
Query: 209 ADEANRTL-NDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIK-------VSLTTQLED 364
A TL + + +K K +E L + E + S + ++K S + QL
Sbjct: 670 GRGAGATLEHQQEISKIKSELEKKVLFYEEELVRREASHVLEVKNVKKEVHDSESHQLAL 729
Query: 365 TKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSK 544
K + + + + + +E + I+++ E E D ++L+ N + + K
Sbjct: 730 QKEILMLKDKLEKSKRERHNEMEEAVGTIKDKYERERAMLFDENKKLTAENEKLCSFVDK 789
Query: 545 YESEGVARSEELEEAKRKLQARLAEAEETIESLNQKV 655
++ +EL++ K ++ +A E I + Q V
Sbjct: 790 LTAQNRQLEDELQDLAAKKES-VAHWEAQIAEIIQWV 825
>BC047871-1|AAH47871.1| 933|Homo sapiens CDC42BPB protein protein.
Length = 933
Score = 53.6 bits (123), Expect = 8e-07
Identities = 54/207 (26%), Positives = 108/207 (52%), Gaps = 3/207 (1%)
Frame = +2
Query: 110 DLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLR 289
D++ L+H S + A E+ +++L+ + E+ K E+ +T+ L + + LS N D +
Sbjct: 429 DVQRDLEH-SLQMEAYERRIRRLEQEKLELSRKLQESTQTVQSLHGSSRALSNSNRD--K 485
Query: 290 QLEEAESQVSQL-SKIKVS--LTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQ 460
++++ ++ +L +KI S L QLEDT L E RE +T + R LE +R++
Sbjct: 486 EIKKLNEEIERLKNKIADSNRLERQLEDTVALRQE--REDSTQ--RLRGLEKQHRVVRQE 541
Query: 461 VEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIES 640
EE L +QL +A+ + ++++EL++A ++ + L E E
Sbjct: 542 KEE-------LHKQLVEASERLK-----------SQAKELKDAHQQRKLALQEFSE---- 579
Query: 641 LNQKVVALEKTKQRLATEVEDLQLEVD 721
LN+++ L KQ+++ ++ D + E++
Sbjct: 580 LNERMAELRAQKQKVSRQLRDKEEEME 606
Score = 32.7 bits (71), Expect = 1.5
Identities = 42/217 (19%), Positives = 93/217 (42%), Gaps = 10/217 (4%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLN--EVQSK 208
+++D + + +AEK R + ++++D A + E KQ++ +L +V+
Sbjct: 610 QKVDAMRQEMRRAEKLRKELEAQLDDAVAEASKERKLREHSENFCKQMESELEALKVKQG 669
Query: 209 ADEANRTL-NDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIK-------VSLTTQLED 364
A TL + + +K K +E L + E + S + ++K S + QL
Sbjct: 670 GRGAGATLEHQQEISKIKSELEKKVLFYEEELVRREASHVLEVKNVKKEVHDSESHQLAL 729
Query: 365 TKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSK 544
K + + + + + +E + I+++ E E D ++L+ N + + K
Sbjct: 730 QKEILMLKDKLEKSKRERHNEMEEAVGTIKDKYERERAMLFDENKKLTAENEKLCSFVDK 789
Query: 545 YESEGVARSEELEEAKRKLQARLAEAEETIESLNQKV 655
++ +EL++ K ++ +A E I + Q V
Sbjct: 790 LTAQNRQLEDELQDLAAKKES-VAHWEAQIAEIIQWV 825
>AF128625-1|AAD37506.1| 1711|Homo sapiens CDC42-binding protein
kinase beta protein.
Length = 1711
Score = 53.6 bits (123), Expect = 8e-07
Identities = 54/207 (26%), Positives = 108/207 (52%), Gaps = 3/207 (1%)
Frame = +2
Query: 110 DLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLR 289
D++ L+H S + A E+ +++L+ + E+ K E+ +T+ L + + LS N D +
Sbjct: 429 DVQRDLEH-SLQMEAYERRIRRLEQEKLELSRKLQESTQTVQSLHGSSRALSNSNRD--K 485
Query: 290 QLEEAESQVSQL-SKIKVS--LTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQ 460
++++ ++ +L +KI S L QLEDT L E RE +T + R LE +R++
Sbjct: 486 EIKKLNEEIERLKNKIADSNRLERQLEDTVALRQE--REDSTQ--RLRGLEKQHRVVRQE 541
Query: 461 VEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIES 640
EE L +QL +A+ + ++++EL++A ++ + L E E
Sbjct: 542 KEE-------LHKQLVEASERLK-----------SQAKELKDAHQQRKLALQEFSE---- 579
Query: 641 LNQKVVALEKTKQRLATEVEDLQLEVD 721
LN+++ L KQ+++ ++ D + E++
Sbjct: 580 LNERMAELRAQKQKVSRQLRDKEEEME 606
Score = 32.7 bits (71), Expect = 1.5
Identities = 42/217 (19%), Positives = 93/217 (42%), Gaps = 10/217 (4%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLN--EVQSK 208
+++D + + +AEK R + ++++D A + E KQ++ +L +V+
Sbjct: 610 QKVDAMRQEMRRAEKLRKELEAQLDDAVAEASKERKLREHSENFCKQMESELEALKVKQG 669
Query: 209 ADEANRTL-NDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIK-------VSLTTQLED 364
A TL + + +K K +E L + E + S + ++K S + QL
Sbjct: 670 GRGAGATLEHQQEISKIKSELEKKVLFYEEELVRREASHVLEVKNVKKEVHDSESHQLAL 729
Query: 365 TKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSK 544
K + + + + + +E + I+++ E E D ++L+ N + + K
Sbjct: 730 QKEILMLKDKLEKSKRERHNEMEEAVGTIKDKYERERAMLFDENKKLTAENEKLCSFVDK 789
Query: 545 YESEGVARSEELEEAKRKLQARLAEAEETIESLNQKV 655
++ +EL++ K ++ +A E I + Q V
Sbjct: 790 LTAQNRQLEDELQDLAAKKES-VAHWEAQIAEIIQWV 825
>AB032950-1|BAA86438.2| 1760|Homo sapiens KIAA1124 protein protein.
Length = 1760
Score = 53.6 bits (123), Expect = 8e-07
Identities = 54/207 (26%), Positives = 108/207 (52%), Gaps = 3/207 (1%)
Frame = +2
Query: 110 DLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLR 289
D++ L+H S + A E+ +++L+ + E+ K E+ +T+ L + + LS N D +
Sbjct: 478 DVQRDLEH-SLQMEAYERRIRRLEQEKLELSRKLQESTQTVQSLHGSSRALSNSNRD--K 534
Query: 290 QLEEAESQVSQL-SKIKVS--LTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQ 460
++++ ++ +L +KI S L QLEDT L E RE +T + R LE +R++
Sbjct: 535 EIKKLNEEIERLKNKIADSNRLERQLEDTVALRQE--REDSTQ--RLRGLEKQHRVVRQE 590
Query: 461 VEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIES 640
EE L +QL +A+ + ++++EL++A ++ + L E E
Sbjct: 591 KEE-------LHKQLVEASERLK-----------SQAKELKDAHQQRKLALQEFSE---- 628
Query: 641 LNQKVVALEKTKQRLATEVEDLQLEVD 721
LN+++ L KQ+++ ++ D + E++
Sbjct: 629 LNERMAELRAQKQKVSRQLRDKEEEME 655
Score = 32.7 bits (71), Expect = 1.5
Identities = 42/217 (19%), Positives = 93/217 (42%), Gaps = 10/217 (4%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLN--EVQSK 208
+++D + + +AEK R + ++++D A + E KQ++ +L +V+
Sbjct: 659 QKVDAMRQEMRRAEKLRKELEAQLDDAVAEASKERKLREHSENFCKQMESELEALKVKQG 718
Query: 209 ADEANRTL-NDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIK-------VSLTTQLED 364
A TL + + +K K +E L + E + S + ++K S + QL
Sbjct: 719 GRGAGATLEHQQEISKIKSELEKKVLFYEEELVRREASHVLEVKNVKKEVHDSESHQLAL 778
Query: 365 TKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSK 544
K + + + + + +E + I+++ E E D ++L+ N + + K
Sbjct: 779 QKEILMLKDKLEKSKRERHNEMEEAVGTIKDKYERERAMLFDENKKLTAENEKLCSFVDK 838
Query: 545 YESEGVARSEELEEAKRKLQARLAEAEETIESLNQKV 655
++ +EL++ K ++ +A E I + Q V
Sbjct: 839 LTAQNRQLEDELQDLAAKKES-VAHWEAQIAEIIQWV 874
>U43195-1|AAB02814.1| 1354|Homo sapiens Rho-associated, coiled-coil
containing protein kinase p160ROCK protein.
Length = 1354
Score = 53.2 bits (122), Expect = 1e-06
Identities = 67/256 (26%), Positives = 112/256 (43%), Gaps = 17/256 (6%)
Frame = +2
Query: 5 SAGRFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQ--- 175
S + + + EQL +LK + E+ +++ + LD N++ E V Q
Sbjct: 427 SLQKTIYKLEEQLHNEMQLKDEMEQKCRTSNIKLDKIMKELDEEGNQRRNLESTVSQIEK 486
Query: 176 ----LQHQLNEVQSKADEANRTLNDLDAAKKKLSIEN--SDLLRQLEEAE--SQVSQLSK 331
LQH++NE Q KA++ N +K+ ++EN S L QLE+ + SQ SQL+
Sbjct: 487 EKMLLQHRINEYQRKAEQEN---------EKRRNVENEVSTLKDQLEDLKKVSQNSQLAN 537
Query: 332 IKVS-LTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLS 508
K+S L QLE+ L E+ L + + + E E L+ S
Sbjct: 538 EKLSQLQKQLEEANDLLRTESDTAVRLRKSHTEMSKSISQLESLNRELQERNRILENSKS 597
Query: 509 KANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLN---QKVVALEKTKQ 679
+ + + ++ E+E R + E LQAR+ +E ++ L +KV K Q
Sbjct: 598 QTDKDYYQLQAILEAERRDRGHD-SEMIGDLQARITSLQEEVKHLKHNLEKVEGERKEAQ 656
Query: 680 RLA--TEVEDLQLEVD 721
+ +E E LE+D
Sbjct: 657 DMLNHSEKEKNNLEID 672
Score = 48.0 bits (109), Expect = 4e-05
Identities = 44/173 (25%), Positives = 81/173 (46%), Gaps = 3/173 (1%)
Frame = +2
Query: 134 LSNEKAAQEKI---VKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEA 304
L E+ A+EK V Q++ Q + + ++ + L L K+++ E +L QLE+
Sbjct: 720 LKEEREAREKAENRVVQIEKQCSMLDVDLKQSQQKLEHLTGNKERMEDEVKNLTLQLEQE 779
Query: 305 ESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGK 484
++ L + + ++ K L + +E TLL R LE +L + +Q
Sbjct: 780 SNKRLLLQNELKTQAFEADNLKGLEKQMKQEINTLLEAKRLLEFELAQLTKQYRGNEGQM 839
Query: 485 ADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESL 643
+LQ QL AE Q + + Y+++ EE+EE R+ ++ E + E+L
Sbjct: 840 RELQDQL---EAE-QYFSTLYKTQVKELKEEIEEKNRENLKKIQELQNEKETL 888
>U31906-1|AAC51791.1| 2083|Homo sapiens golgin-245 protein.
Length = 2083
Score = 53.2 bits (122), Expect = 1e-06
Identities = 47/203 (23%), Positives = 93/203 (45%), Gaps = 15/203 (7%)
Frame = +2
Query: 143 EKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQ 322
E A K ++ LQ ++ ++ T+ L+ E L QL+E ++ +
Sbjct: 128 EDGASVKTLETLQQRVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQLDERLQELEK 187
Query: 323 LSKI----KVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKAD 490
+ + K L TQL D K L ++ +++ ++ + + H E +E + E A
Sbjct: 188 IKDLHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMH------ETLEMKEEEIAQ 241
Query: 491 LQRQLSKANAEAQLWRSKYESEGVARSEELEEA----------KRKLQARLAEAEETIES 640
L+ ++ + + + R + E A EELE+A +RKL+A + E +TIE
Sbjct: 242 LRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEK 301
Query: 641 LNQKV-VALEKTKQRLATEVEDL 706
+++ ++L++ R+ EV D+
Sbjct: 302 TSEEERISLQQELSRVKQEVVDV 324
Score = 47.6 bits (108), Expect = 5e-05
Identities = 39/225 (17%), Positives = 100/225 (44%)
Frame = +2
Query: 32 GEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKA 211
G Q ++ ++ + + + +N + + L +K + KQL ++Q+
Sbjct: 1183 GNQQQAASEKESCITQLKKELSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSI 1242
Query: 212 DEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEA 391
+ + + + +K+ E +LL Q+++ +V LSK K+S Q++D E
Sbjct: 1243 SLSEKEAA-ISSLRKQYDEEKCELLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWK 1301
Query: 392 RERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARS 571
++ + +F ++ + ++ Q+E +++ + Q++ E +++
Sbjct: 1302 KKAQS---RFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFD----CLK 1354
Query: 572 EELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDL 706
E+E+ K K++ + + E ++S +++ LE + E+E L
Sbjct: 1355 GEMEDDKSKMEKKESNLETELKSQTARIMELEDHITQKTIEIESL 1399
Score = 44.4 bits (100), Expect = 5e-04
Identities = 50/244 (20%), Positives = 108/244 (44%), Gaps = 17/244 (6%)
Frame = +2
Query: 44 DQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIV--KQLQHQLNEVQSKADE 217
+Q+ KL+ EK A+ + +L L E Q K+ K L Q K +
Sbjct: 331 EQIAKLQKLHEKELAR---KEQELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKEQQ 387
Query: 218 ANRTLNDLDAAKKKLSIENSDLLRQLE-EAESQVSQLSKIKVSLTTQLEDTKR------- 373
+ L +L+ KK + E+ + LR L+ EAE+ +++ +++ SL L++ +
Sbjct: 388 ESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENENQSKDLAV 447
Query: 374 -LADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYE 550
L E+ + + + +L++++ Q + + + +Q + E + + E
Sbjct: 448 HLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWAEELQVLKQQYQTEMEKLREKCEQE 507
Query: 551 SEGVARSEEL------EEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQL 712
E + + +E+ EE K +L + +ESL+ ++ + K + +L E+ L+
Sbjct: 508 KETLLKDKEIIFQAHIEEMNEKTLEKLDVNQTELESLSSELSEVLKARHKLEEELSVLKD 567
Query: 713 EVDR 724
+ D+
Sbjct: 568 QTDK 571
Score = 44.4 bits (100), Expect = 5e-04
Identities = 49/198 (24%), Positives = 102/198 (51%), Gaps = 7/198 (3%)
Frame = +2
Query: 152 AQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKL-------SIENSDLLRQLEEAES 310
A E+ + QLQ +L +++++ + + +++A KK + I+ DL++QLE+ S
Sbjct: 671 AYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNS 730
Query: 311 QVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKAD 490
++ Q K+K SLT E ++E + +L + N+ + +RE ++E E
Sbjct: 731 EMEQ--KVK-SLTQVYESKLEDGNKEQEQTKQILVEKENM---ILQMREGQKKEIE---I 781
Query: 491 LQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEK 670
L ++LS + +YE++ + +++E+ K+K A+E E+L +K++ E
Sbjct: 782 LTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQK-------AKEMQETLKKKLLDQE- 833
Query: 671 TKQRLATEVEDLQLEVDR 724
+L E+E+ LE+ +
Sbjct: 834 --AKLKKELENTALELSQ 849
Score = 36.7 bits (81), Expect = 0.094
Identities = 41/198 (20%), Positives = 84/198 (42%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD 214
E ++ +K K + ++ NDL L EK K + +LQ L ++ +
Sbjct: 1757 ENTEEKSKSHLVQPKLLSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEHQ 1816
Query: 215 EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEAR 394
+ +L+ KK+ E + ++Q E+ + ++ S +K + E +LA +E
Sbjct: 1817 Q------ELEILKKEYDQEREEKIKQ-EQEDLELKHNSTLKQLMR---EFNTQLAQKEQE 1866
Query: 395 ERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSE 574
T+ + + E +EE L +++++ + + + +YE AR E
Sbjct: 1867 LEMTIKETINKAQEVEAELLESHQEETN---QLLKKIAEKDDDLKRTAKRYEEILDAREE 1923
Query: 575 ELEEAKRKLQARLAEAEE 628
E+ R LQ +L E ++
Sbjct: 1924 EMTAKVRDLQTQLEELQK 1941
>BC146657-1|AAI46658.1| 771|Homo sapiens CGN protein protein.
Length = 771
Score = 53.2 bits (122), Expect = 1e-06
Identities = 51/240 (21%), Positives = 108/240 (45%), Gaps = 5/240 (2%)
Frame = +2
Query: 14 RFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLN 193
R + + E+ +L +L + + Q E+ +++ LD + + E V +LQ++L
Sbjct: 388 RQLEEKTEECSRLQELLERRKGEAQQSNKELQNMKRLLDQGEDLRHGLETQVMELQNKLK 447
Query: 194 EVQSKADEANRTLNDLDAAKKKLS--IENSDLLR-QLEEAESQVSQLS-KIKVSLTTQLE 361
VQ L DL ++ L +E + QL E +++ L +K + ++ +
Sbjct: 448 HVQGPEPAKEVLLKDLLETRELLEEVLEGKQRVEEQLRLRERELTALKGALKEEVASRDQ 507
Query: 362 DTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRS 541
+ + + + R+ L ++ D + + ++ + LQR+L + + E W+S
Sbjct: 508 EVEHVRQQYQRDTEQLRRSMQDATQDHAVLEAERQKMSALVRGLQRELEETSEETGHWQS 567
Query: 542 KYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEK-TKQRLATEVEDLQLEV 718
++ E+L K++L E EE E L +K+ L++ +Q A+ + Q+EV
Sbjct: 568 MFQK----NKEDLRATKQELLQLRMEKEEMEEELGEKIEVLQRELEQARASAGDTRQVEV 623
>AY640415-1|AAT68295.1| 284|Homo sapiens tropomyosin alpha striated
muscle isoform protein.
Length = 284
Score = 53.2 bits (122), Expect = 1e-06
Identities = 53/226 (23%), Positives = 102/226 (45%), Gaps = 5/226 (2%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD 214
++L L K E +Y + D + L+ + E V L ++ V+ + D
Sbjct: 41 DELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELD 100
Query: 215 EANR----TLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLAD 382
A L L+ A+K + + S+ ++ E+ +Q + K+++ QL++ K +A+
Sbjct: 101 RAQERLATALQKLEEAEK--AADESERGMKVIESRAQKDE-EKMEIQ-EIQLKEAKHIAE 156
Query: 383 EEARERATLLGKFRNLEHDLDNIREQVEEEAEGK-ADLQRQLSKANAEAQLWRSKYESEG 559
+ R+ + K +E DL+ E+ E +EGK A+L+ +L + + ++ E
Sbjct: 157 DADRKYEEVARKLVIIESDLERAEERAEL-SEGKCAELEEELKTVTNDLKSLEAQAEKYS 215
Query: 560 VARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEV 697
+ + EE + L +L EAE E + V LEK+ L E+
Sbjct: 216 -QKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDEL 260
>AB208965-1|BAD92202.1| 705|Homo sapiens Rho-associated,
coiled-coil containing protein kinase 1 variant protein.
Length = 705
Score = 53.2 bits (122), Expect = 1e-06
Identities = 67/256 (26%), Positives = 112/256 (43%), Gaps = 17/256 (6%)
Frame = +2
Query: 5 SAGRFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQ--- 175
S + + + EQL +LK + E+ +++ + LD N++ E V Q
Sbjct: 105 SLQKTIYKLEEQLHNEMQLKDEMEQKCRTSNIKLDKIMKELDEEGNQRRNLESTVSQIEK 164
Query: 176 ----LQHQLNEVQSKADEANRTLNDLDAAKKKLSIEN--SDLLRQLEEAE--SQVSQLSK 331
LQH++NE Q KA++ N +K+ ++EN S L QLE+ + SQ SQL+
Sbjct: 165 EKMLLQHRINEYQRKAEQEN---------EKRRNVENEVSTLKDQLEDLKKVSQNSQLAN 215
Query: 332 IKVS-LTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLS 508
K+S L QLE+ L E+ L + + + E E L+ S
Sbjct: 216 EKLSQLQKQLEEANDLLRTESDTAVRLRKSHTEMSKSISQLESLNRELQERNRILENSKS 275
Query: 509 KANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLN---QKVVALEKTKQ 679
+ + + ++ E+E R + E LQAR+ +E ++ L +KV K Q
Sbjct: 276 QTDKDYYQLQAILEAERRDRGHD-SEMIGDLQARITSLQEEVKHLKHNLEKVEGERKEAQ 334
Query: 680 RLA--TEVEDLQLEVD 721
+ +E E LE+D
Sbjct: 335 DMLNHSEKEKNNLEID 350
Score = 48.0 bits (109), Expect = 4e-05
Identities = 44/173 (25%), Positives = 81/173 (46%), Gaps = 3/173 (1%)
Frame = +2
Query: 134 LSNEKAAQEKI---VKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEA 304
L E+ A+EK V Q++ Q + + ++ + L L K+++ E +L QLE+
Sbjct: 398 LKEEREAREKAENRVVQIEKQCSMLDVDLKQSQQKLEHLTGNKERMEDEVKNLTLQLEQE 457
Query: 305 ESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGK 484
++ L + + ++ K L + +E TLL R LE +L + +Q
Sbjct: 458 SNKRLLLQNELKTQAFEADNLKGLEKQMKQEINTLLEAKRLLEFELAQLTKQYRGNEGQM 517
Query: 485 ADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESL 643
+LQ QL AE Q + + Y+++ EE+EE R+ ++ E + E+L
Sbjct: 518 RELQDQL---EAE-QYFSTLYKTQVKELKEEIEEKNRENLKKIQELQNEKETL 566
>Y00067-1|CAA68276.1| 916|Homo sapiens NF-M protein.
Length = 916
Score = 52.8 bits (121), Expect = 1e-06
Identities = 48/228 (21%), Positives = 110/228 (48%), Gaps = 4/228 (1%)
Frame = +2
Query: 38 QLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADE 217
++ L + +A + Y E+ +LRA L+ +++EKA + L+ ++ ++ + +E
Sbjct: 132 EIQALRQKQASHAQLGDAYDQEIRELRATLEMVNHEKAQVQLDSDHLEEDIHRLKERFEE 191
Query: 218 ANRTLNDLDAAKKKL--SIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEA 391
R +D +AA + L IE + L++ E + +V L L + E+ +AD A
Sbjct: 192 EARLRDDTEAAIRALRKDIEEASLVK--VELDKKVQSLQDEVAFLRSNHEE--EVADLLA 247
Query: 392 RERATLLGKFRN--LEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVA 565
+ +A+ + R L+ D+ +++ + E +D +A+ W ++
Sbjct: 248 QIQASHITVERKDYLKTDISTALKEIRSQLESHSDQNMH------QAEEWFKCRYAKLTE 301
Query: 566 RSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQ 709
+E+ +EA R + +AE ++S + ++ ++ TK+ L ++ D++
Sbjct: 302 AAEQNKEAIRSAKEEIAEYRRQLQSKSIELESVRGTKESLERQLSDIE 349
>EF560737-1|ABQ59047.1| 877|Homo sapiens NEFM protein protein.
Length = 877
Score = 52.8 bits (121), Expect = 1e-06
Identities = 48/228 (21%), Positives = 110/228 (48%), Gaps = 4/228 (1%)
Frame = +2
Query: 38 QLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADE 217
++ L + +A + Y E+ +LRA L+ +++EKA + L+ ++ ++ + +E
Sbjct: 132 EIQALRQKQASHAQLGDAYDQEIRELRATLEMVNHEKAQVQLDSDHLEEDIHRLKERFEE 191
Query: 218 ANRTLNDLDAAKKKL--SIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEA 391
R +D +AA + L IE + L++ E + +V L L + E+ +AD A
Sbjct: 192 EARLRDDTEAAIRALRKDIEEASLVK--VELDKKVQSLQDEVAFLRSNHEE--EVADLLA 247
Query: 392 RERATLLGKFRN--LEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVA 565
+ +A+ + R L+ D+ +++ + E +D +A+ W ++
Sbjct: 248 QIQASHITVERKDYLKTDISTALKEIRSQLESHSDQNMH------QAEEWFKCRYAKLTE 301
Query: 566 RSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQ 709
+E+ +EA R + +AE ++S + ++ ++ TK+ L ++ D++
Sbjct: 302 AAEQNKEAIRSAKEEIAEYRRQLQSKSIELESVRGTKESLERQLSDIE 349
>EF560736-1|ABQ59046.1| 916|Homo sapiens NEFM protein protein.
Length = 916
Score = 52.8 bits (121), Expect = 1e-06
Identities = 48/228 (21%), Positives = 110/228 (48%), Gaps = 4/228 (1%)
Frame = +2
Query: 38 QLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADE 217
++ L + +A + Y E+ +LRA L+ +++EKA + L+ ++ ++ + +E
Sbjct: 132 EIQALRQKQASHAQLGDAYDQEIRELRATLEMVNHEKAQVQLDSDHLEEDIHRLKERFEE 191
Query: 218 ANRTLNDLDAAKKKL--SIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEA 391
R +D +AA + L IE + L++ E + +V L L + E+ +AD A
Sbjct: 192 EARLRDDTEAAIRALRKDIEEASLVK--VELDKKVQSLQDEVAFLRSNHEE--EVADLLA 247
Query: 392 RERATLLGKFRN--LEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVA 565
+ +A+ + R L+ D+ +++ + E +D +A+ W ++
Sbjct: 248 QIQASHITVERKDYLKTDISTALKEIRSQLESHSDQNMH------QAEEWFKCRYAKLTE 301
Query: 566 RSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQ 709
+E+ +EA R + +AE ++S + ++ ++ TK+ L ++ D++
Sbjct: 302 AAEQNKEAIRSAKEEIAEYRRQLQSKSIELESVRGTKESLERQLSDIE 349
>BC109126-1|AAI09127.1| 872|Homo sapiens chromosome 10 open reading
frame 80 protein.
Length = 872
Score = 52.8 bits (121), Expect = 1e-06
Identities = 43/233 (18%), Positives = 107/233 (45%), Gaps = 1/233 (0%)
Frame = +2
Query: 23 SDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQ 202
+DM + ++ L+ +K + + L+ + NE+AA+E ++Q Q + ++Q
Sbjct: 230 ADMDSRQTEIKALQQYVQKSKEELQKLEQQLKE--QKILNERAAKE--LEQFQMRNAKLQ 285
Query: 203 SKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLAD 382
+ ++ + L ++ ++E ++ + + +L+KI+ + +L T+
Sbjct: 286 QENEQHSLVCEQLSQENQQKALELKAKEEEVHQMRLDIGKLNKIREQIHKKLHHTEDQKA 345
Query: 383 EEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGV 562
E + + TL + LE +++ ++Q E + + +L R+ N + ++ ++
Sbjct: 346 EVEQHKETLKNQIVGLEREVEASKKQAELDRKAMDELLRERDILNKN--MLKAVNATQKQ 403
Query: 563 ARSEEL-EEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEV 718
+L E+AKR L+ + ++ + + + LEK + R + DL +V
Sbjct: 404 TDLVKLHEQAKRNLEGEIQNYKDEAQKQRKIIFHLEKERDRYINQASDLTQKV 456
Score = 39.5 bits (88), Expect = 0.013
Identities = 46/230 (20%), Positives = 97/230 (42%), Gaps = 1/230 (0%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD 214
+ +D + KA++ E+ +L ++ S Q ++ L EV + D
Sbjct: 104 KMVDSAYDKEQKAKETILALKEEIVNLTKLVEQGSGLSMDQHSNIRDLLRFKEEVTKERD 163
Query: 215 EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEAR 394
+ + L + + + + + R EEAE +SQ + +++ + A E R
Sbjct: 164 QLLSEVVKLRESLAQTTEQQQETERSKEEAEHAISQFQQ-------EIQQRQNEASREFR 216
Query: 395 ERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARS- 571
++ L + + ++ D+D+ + +++ + + +L K E QL K +E A+
Sbjct: 217 KKEKLEKELKQIQADMDSRQTEIKALQQYVQKSKEELQK--LEQQLKEQKILNERAAKEL 274
Query: 572 EELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
E+ + KLQ + E L+Q+ +K + A E E Q+ +D
Sbjct: 275 EQFQMRNAKLQQENEQHSLVCEQLSQE--NQQKALELKAKEEEVHQMRLD 322
>BC101517-1|AAI01518.1| 637|Homo sapiens RAB11 family interacting
protein 4 (class II) protein.
Length = 637
Score = 52.8 bits (121), Expect = 1e-06
Identities = 49/220 (22%), Positives = 97/220 (44%), Gaps = 2/220 (0%)
Frame = +2
Query: 59 LKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRT-LN 235
LK+K ++ Q V++L + + +++ E+ +++ + E K + T +
Sbjct: 364 LKSKLKQENTQLVHRVHELE---EMVKDQETTAEQALEEEARRHREAYGKLEREKATEVE 420
Query: 236 DLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTK-RLADEEARERATLL 412
L+A ++L EN++L + +SQ +L + + ++ +LEDT RL DE +
Sbjct: 421 LLNARVQQLEEENTELRTTVTRLKSQTEKLDEERQRMSDRLEDTSLRLKDE--------M 472
Query: 413 GKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAK 592
++ + L R + ++E E +L L K Q+++ E G RS +
Sbjct: 473 DLYKRMMDKLRQNRLEFQKEREATQELIEDLRKELEHLQMYKLDCERPGRGRSASSGLGE 532
Query: 593 RKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQL 712
+AR E E ++ L Q+ L L ++ L L
Sbjct: 533 FNARAREVELEHEVKRLKQENYKLRDQNDDLNGQILSLSL 572
Score = 35.5 bits (78), Expect = 0.22
Identities = 49/211 (23%), Positives = 89/211 (42%), Gaps = 6/211 (2%)
Frame = +2
Query: 104 VNDLRAGLDHLS----NEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIE 271
+NDL A L +L N K + +QL H N S + + +D+
Sbjct: 284 LNDLEARLKNLKANSPNRKISSTAFGRQLMHSSNFSSSNGSTEDLFRDSIDSC------- 336
Query: 272 NSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNI 451
++D+ ++ E +V++L SLT D K +E + + + + D +
Sbjct: 337 DNDITEKVSFLEKKVTELEND--SLTNG--DLKSKLKQENTQLVHRVHELEEMVKDQETT 392
Query: 452 REQ-VEEEAEGKADLQRQLSKANA-EAQLWRSKYESEGVARSEELEEAKRKLQARLAEAE 625
EQ +EEEA + +L + A E +L AR ++LEE +L+
Sbjct: 393 AEQALEEEARRHREAYGKLEREKATEVELLN--------ARVQQLEEENTELRT------ 438
Query: 626 ETIESLNQKVVALEKTKQRLATEVEDLQLEV 718
T+ L + L++ +QR++ +ED L +
Sbjct: 439 -TVTRLKSQTEKLDEERQRMSDRLEDTSLRL 468
Score = 30.7 bits (66), Expect = 6.2
Identities = 33/147 (22%), Positives = 62/147 (42%), Gaps = 4/147 (2%)
Frame = +2
Query: 41 LDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEK--IVKQLQHQLNEVQSKAD 214
+D+L + + + +K R + DLR L+HL K E+ + L E ++A
Sbjct: 479 MDKLRQNRLEFQKEREATQELIEDLRKELEHLQMYKLDCERPGRGRSASSGLGEFNARAR 538
Query: 215 EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLS--KIKVSLTTQLEDTKRLADEE 388
E +L+ K+L EN L Q ++ Q+ LS + K Q + A+ +
Sbjct: 539 EV-----ELEHEVKRLKQENYKLRDQNDDLNGQILSLSLYEAKNLFAAQTKAQSLAAEID 593
Query: 389 ARERATLLGKFRNLEHDLDNIREQVEE 469
R L+ + E +R+ +++
Sbjct: 594 TASRDELMEALKEQEEINFRLRQYMDK 620
>BC096757-1|AAH96757.1| 916|Homo sapiens neurofilament, medium
polypeptide 150kDa protein.
Length = 916
Score = 52.8 bits (121), Expect = 1e-06
Identities = 48/228 (21%), Positives = 110/228 (48%), Gaps = 4/228 (1%)
Frame = +2
Query: 38 QLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADE 217
++ L + +A + Y E+ +LRA L+ +++EKA + L+ ++ ++ + +E
Sbjct: 132 EIQALRQKQASHAQLGDAYDQEIRELRATLEMVNHEKAQVQLDSDHLEEDIHRLKERFEE 191
Query: 218 ANRTLNDLDAAKKKL--SIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEA 391
R +D +AA + L IE + L++ E + +V L L + E+ +AD A
Sbjct: 192 EARLRDDTEAAIRALRKDIEEASLVK--VELDKKVQSLQDEVAFLRSNHEE--EVADLLA 247
Query: 392 RERATLLGKFRN--LEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVA 565
+ +A+ + R L+ D+ +++ + E +D +A+ W ++
Sbjct: 248 QIQASHITVERKDYLKTDISTALKEIRSQLESHSDQNMH------QAEEWFKCRYAKLTE 301
Query: 566 RSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQ 709
+E+ +EA R + +AE ++S + ++ ++ TK+ L ++ D++
Sbjct: 302 AAEQNKEAIRSAKEEIAEYRRQLQSKSIELESVRGTKESLERQLSDIE 349
>BC093914-1|AAH93914.1| 637|Homo sapiens RAB11 family interacting
protein 4 (class II) protein.
Length = 637
Score = 52.8 bits (121), Expect = 1e-06
Identities = 49/220 (22%), Positives = 97/220 (44%), Gaps = 2/220 (0%)
Frame = +2
Query: 59 LKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRT-LN 235
LK+K ++ Q V++L + + +++ E+ +++ + E K + T +
Sbjct: 364 LKSKLKQENTQLVHRVHELE---EMVKDQETTAEQALEEEARRHREAYGKLEREKATEVE 420
Query: 236 DLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTK-RLADEEARERATLL 412
L+A ++L EN++L + +SQ +L + + ++ +LEDT RL DE +
Sbjct: 421 LLNARVQQLEEENTELRTTVTRLKSQTEKLDEERQRMSDRLEDTSLRLKDE--------M 472
Query: 413 GKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAK 592
++ + L R + ++E E +L L K Q+++ E G RS +
Sbjct: 473 DLYKRMMDKLRQNRLEFQKEREATQELIEDLRKELEHLQMYKLDCERPGRGRSASSGLGE 532
Query: 593 RKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQL 712
+AR E E ++ L Q+ L L ++ L L
Sbjct: 533 FNARAREVELEHEVKRLKQENYKLRDQNDDLNGQILSLSL 572
Score = 35.5 bits (78), Expect = 0.22
Identities = 49/211 (23%), Positives = 89/211 (42%), Gaps = 6/211 (2%)
Frame = +2
Query: 104 VNDLRAGLDHLS----NEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIE 271
+NDL A L +L N K + +QL H N S + + +D+
Sbjct: 284 LNDLEARLKNLKANSPNRKISSTAFGRQLMHSSNFSSSNGSTEDLFRDSIDSC------- 336
Query: 272 NSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNI 451
++D+ ++ E +V++L SLT D K +E + + + + D +
Sbjct: 337 DNDITEKVSFLEKKVTELEND--SLTNG--DLKSKLKQENTQLVHRVHELEEMVKDQETT 392
Query: 452 REQ-VEEEAEGKADLQRQLSKANA-EAQLWRSKYESEGVARSEELEEAKRKLQARLAEAE 625
EQ +EEEA + +L + A E +L AR ++LEE +L+
Sbjct: 393 AEQALEEEARRHREAYGKLEREKATEVELLN--------ARVQQLEEENTELRT------ 438
Query: 626 ETIESLNQKVVALEKTKQRLATEVEDLQLEV 718
T+ L + L++ +QR++ +ED L +
Sbjct: 439 -TVTRLKSQTEKLDEERQRMSDRLEDTSLRL 468
Score = 30.7 bits (66), Expect = 6.2
Identities = 33/147 (22%), Positives = 62/147 (42%), Gaps = 4/147 (2%)
Frame = +2
Query: 41 LDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEK--IVKQLQHQLNEVQSKAD 214
+D+L + + + +K R + DLR L+HL K E+ + L E ++A
Sbjct: 479 MDKLRQNRLEFQKEREATQELIEDLRKELEHLQMYKLDCERPGRGRSASSGLGEFNARAR 538
Query: 215 EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLS--KIKVSLTTQLEDTKRLADEE 388
E +L+ K+L EN L Q ++ Q+ LS + K Q + A+ +
Sbjct: 539 EV-----ELEHEVKRLKQENYKLRDQNDDLNGQILSLSLYEAKNLFAAQTKAQSLAAEID 593
Query: 389 ARERATLLGKFRNLEHDLDNIREQVEE 469
R L+ + E +R+ +++
Sbjct: 594 TASRDELMEALKEQEEINFRLRQYMDK 620
>BC053545-1|AAH53545.1| 245|Homo sapiens tropomyosin 1 (alpha)
protein.
Length = 245
Score = 52.8 bits (121), Expect = 1e-06
Identities = 53/209 (25%), Positives = 98/209 (46%), Gaps = 5/209 (2%)
Frame = +2
Query: 113 LRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANR----TLNDLDAAKKKLSIENSD 280
L+ LDH + E V L ++ V+ + D A L L+ A+K + + S+
Sbjct: 31 LQRELDHERKLRETAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEK--AADESE 88
Query: 281 LLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQ 460
++ E+ +Q + K+++ QL++ K +A++ R+ + K +E DL+ E+
Sbjct: 89 RGMKVIESRAQKDE-EKMEIQ-EIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEER 146
Query: 461 VEEEAEGK-ADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIE 637
E +EGK A+L+ +L + ++ E + + EE + L +L EAE E
Sbjct: 147 AEL-SEGKCAELEEELKTVTNNLKSLEAQAEKYS-QKEDRYEEEIKVLSDKLKEAETRAE 204
Query: 638 SLNQKVVALEKTKQRLATEVEDLQLEVDR 724
+ V LEK+ L ++ QLE +R
Sbjct: 205 FAERSVTKLEKSIDDLEDQLYQ-QLEQNR 232
>BC050473-1|AAH50473.1| 287|Homo sapiens TPM1 protein protein.
Length = 287
Score = 52.8 bits (121), Expect = 1e-06
Identities = 53/209 (25%), Positives = 98/209 (46%), Gaps = 5/209 (2%)
Frame = +2
Query: 113 LRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANR----TLNDLDAAKKKLSIENSD 280
L+ LDH + E V L ++ V+ + D A L L+ A+K + + S+
Sbjct: 73 LQRELDHERKLRETAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEK--AADESE 130
Query: 281 LLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQ 460
++ E+ +Q + K+++ QL++ K +A++ R+ + K +E DL+ E+
Sbjct: 131 RGMKVIESRAQKDE-EKMEIQ-EIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEER 188
Query: 461 VEEEAEGK-ADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIE 637
E +EGK A+L+ +L + ++ E + + EE + L +L EAE E
Sbjct: 189 AEL-SEGKCAELEEELKTVTNNLKSLEAQAEKYS-QKEDRYEEEIKVLSDKLKEAETRAE 246
Query: 638 SLNQKVVALEKTKQRLATEVEDLQLEVDR 724
+ V LEK+ L ++ QLE +R
Sbjct: 247 FAERSVTKLEKSIDDLEDQLYQ-QLEQNR 274
>BC036225-1|AAH36225.1| 872|Homo sapiens chromosome 10 open reading
frame 80 protein.
Length = 872
Score = 52.8 bits (121), Expect = 1e-06
Identities = 43/233 (18%), Positives = 107/233 (45%), Gaps = 1/233 (0%)
Frame = +2
Query: 23 SDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQ 202
+DM + ++ L+ +K + + L+ + NE+AA+E ++Q Q + ++Q
Sbjct: 230 ADMDSRQTEIKALQQYVQKSKEELQKLEQQLKE--QKILNERAAKE--LEQFQMRNAKLQ 285
Query: 203 SKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLAD 382
+ ++ + L ++ ++E ++ + + +L+KI+ + +L T+
Sbjct: 286 QENEQHSLVCEQLSQENQQKALELKAKEEEVHQMRLDIGKLNKIREQIHKKLHHTEDQKA 345
Query: 383 EEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGV 562
E + + TL + LE +++ ++Q E + + +L R+ N + ++ ++
Sbjct: 346 EVEQHKETLKNQIVGLEREVEASKKQAELDRKAMDELLRERDILNKN--MLKAVNATQKQ 403
Query: 563 ARSEEL-EEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEV 718
+L E+AKR L+ + ++ + + + LEK + R + DL +V
Sbjct: 404 TDLVKLHEQAKRNLEGEIQNYKDEAQKQRKIIFHLEKERDRYINQASDLTQKV 456
Score = 39.5 bits (88), Expect = 0.013
Identities = 46/230 (20%), Positives = 97/230 (42%), Gaps = 1/230 (0%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD 214
+ +D + KA++ E+ +L ++ S Q ++ L EV + D
Sbjct: 104 KMVDSAYDKEQKAKETILALKEEIVNLTKLVEQGSGLSMDQHSNIRDLLRFKEEVTKERD 163
Query: 215 EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEAR 394
+ + L + + + + + R EEAE +SQ + +++ + A E R
Sbjct: 164 QLLSEVVKLRESLAQTTEQQQETERSKEEAEHAISQFQQ-------EIQQRQNEASREFR 216
Query: 395 ERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARS- 571
++ L + + ++ D+D+ + +++ + + +L K E QL K +E A+
Sbjct: 217 KKEKLEKELKQIQADMDSRQTEIKALQQYVQKSKEELQK--LEQQLKEQKILNERAAKEL 274
Query: 572 EELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
E+ + KLQ + E L+Q+ +K + A E E Q+ +D
Sbjct: 275 EQFQMRNAKLQQENEQHSLVCEQLSQE--NQQKALELKAKEEEVHQMRLD 322
>AY640414-1|AAT68294.1| 284|Homo sapiens sarcomeric tropomyosin
kappa protein.
Length = 284
Score = 52.8 bits (121), Expect = 1e-06
Identities = 54/226 (23%), Positives = 101/226 (44%), Gaps = 5/226 (2%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD 214
E + KL +E R + E++ L A E V L ++ V+ + D
Sbjct: 41 EDIAAKEKLLRVSEDERDRVLEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELD 100
Query: 215 EANR----TLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLAD 382
A L L+ A+K + + S+ ++ E+ +Q + K+++ QL++ K +A+
Sbjct: 101 RAQERLATALQKLEEAEK--AADESERGMKVIESRAQKDE-EKMEIQ-EIQLKEAKHIAE 156
Query: 383 EEARERATLLGKFRNLEHDLDNIREQVEEEAEGK-ADLQRQLSKANAEAQLWRSKYESEG 559
+ R+ + K +E DL+ E+ E +EGK A+L+ +L + + ++ E
Sbjct: 157 DADRKYEEVARKLVIIESDLERAEERAEL-SEGKCAELEEELKTVTNDLKSLEAQAEKYS 215
Query: 560 VARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEV 697
+ + EE + L +L EAE E + V LEK+ L E+
Sbjct: 216 -QKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDEL 260
>AY169244-1|AAO21970.1| 637|Homo sapiens rab11-family interacting
protein 4 protein.
Length = 637
Score = 52.8 bits (121), Expect = 1e-06
Identities = 49/220 (22%), Positives = 97/220 (44%), Gaps = 2/220 (0%)
Frame = +2
Query: 59 LKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRT-LN 235
LK+K ++ Q V++L + + +++ E+ +++ + E K + T +
Sbjct: 364 LKSKLKQENTQLVHRVHELE---EMVKDQETTAEQALEEEARRHREAYGKLEREKATEVE 420
Query: 236 DLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTK-RLADEEARERATLL 412
L+A ++L EN++L + +SQ +L + + ++ +LEDT RL DE +
Sbjct: 421 LLNARVQQLEEENTELRTTVTRLKSQTEKLDEERQRMSDRLEDTSLRLKDE--------M 472
Query: 413 GKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAK 592
++ + L R + ++E E +L L K Q+++ E G RS +
Sbjct: 473 DLYKRMMDKLRQNRLEFQKEREATQELIEDLRKELEHLQMYKLDCERPGRGRSASSGLGE 532
Query: 593 RKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQL 712
+AR E E ++ L Q+ L L ++ L L
Sbjct: 533 FNARAREVELEHEVKRLKQENYKLRDQNDDLNGQILSLSL 572
Score = 35.5 bits (78), Expect = 0.22
Identities = 49/211 (23%), Positives = 89/211 (42%), Gaps = 6/211 (2%)
Frame = +2
Query: 104 VNDLRAGLDHLS----NEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIE 271
+NDL A L +L N K + +QL H N S + + +D+
Sbjct: 284 LNDLEARLKNLKANSPNRKISSTAFGRQLMHSSNFSSSNGSTEDLFRDSIDSC------- 336
Query: 272 NSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNI 451
++D+ ++ E +V++L SLT D K +E + + + + D +
Sbjct: 337 DNDITEKVSFLEKKVTELEND--SLTNG--DLKSKLKQENTQLVHRVHELEEMVKDQETT 392
Query: 452 REQ-VEEEAEGKADLQRQLSKANA-EAQLWRSKYESEGVARSEELEEAKRKLQARLAEAE 625
EQ +EEEA + +L + A E +L AR ++LEE +L+
Sbjct: 393 AEQALEEEARRHREAYGKLEREKATEVELLN--------ARVQQLEEENTELRT------ 438
Query: 626 ETIESLNQKVVALEKTKQRLATEVEDLQLEV 718
T+ L + L++ +QR++ +ED L +
Sbjct: 439 -TVTRLKSQTEKLDEERQRMSDRLEDTSLRL 468
Score = 30.7 bits (66), Expect = 6.2
Identities = 33/147 (22%), Positives = 62/147 (42%), Gaps = 4/147 (2%)
Frame = +2
Query: 41 LDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEK--IVKQLQHQLNEVQSKAD 214
+D+L + + + +K R + DLR L+HL K E+ + L E ++A
Sbjct: 479 MDKLRQNRLEFQKEREATQELIEDLRKELEHLQMYKLDCERPGRGRSASSGLGEFNARAR 538
Query: 215 EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLS--KIKVSLTTQLEDTKRLADEE 388
E +L+ K+L EN L Q ++ Q+ LS + K Q + A+ +
Sbjct: 539 EV-----ELEHEVKRLKQENYKLRDQNDDLNGQILSLSLYEAKNLFAAQTKAQSLAAEID 593
Query: 389 ARERATLLGKFRNLEHDLDNIREQVEE 469
R L+ + E +R+ +++
Sbjct: 594 TASRDELMEALKEQEEINFRLRQYMDK 620
>AL831830-1|CAD38543.1| 296|Homo sapiens hypothetical protein
protein.
Length = 296
Score = 52.8 bits (121), Expect = 1e-06
Identities = 49/220 (22%), Positives = 97/220 (44%), Gaps = 2/220 (0%)
Frame = +2
Query: 59 LKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRT-LN 235
LK+K ++ Q V++L + + +++ E+ +++ + E K + T +
Sbjct: 23 LKSKLKQENTQLVHRVHELE---EMVKDQETTAEQALEEEARRHREAYGKLEREKATEVE 79
Query: 236 DLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTK-RLADEEARERATLL 412
L+A ++L EN++L + +SQ +L + + ++ +LEDT RL DE +
Sbjct: 80 LLNARVQQLEEENTELRTTVTRLKSQTEKLDEERQRMSDRLEDTSLRLKDE--------M 131
Query: 413 GKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAK 592
++ + L R + ++E E +L L K Q+++ E G RS +
Sbjct: 132 DLYKRMMDKLRQNRLEFQKEREATQELIEDLRKELEHLQMYKLDCERPGRGRSASSGLGE 191
Query: 593 RKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQL 712
+AR E E ++ L Q+ L L ++ L L
Sbjct: 192 FNARAREVELEHEVKRLKQENYKLRDQNDDLNGQILSLSL 231
Score = 32.7 bits (71), Expect = 1.5
Identities = 21/97 (21%), Positives = 42/97 (43%)
Frame = +2
Query: 428 LEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQA 607
L H + + E V+++ + ++ + EA K E E E L ++L+
Sbjct: 34 LVHRVHELEEMVKDQETTAEQALEEEARRHREAY---GKLEREKATEVELLNARVQQLEE 90
Query: 608 RLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEV 718
E T+ L + L++ +QR++ +ED L +
Sbjct: 91 ENTELRTTVTRLKSQTEKLDEERQRMSDRLEDTSLRL 127
Score = 30.7 bits (66), Expect = 6.2
Identities = 33/147 (22%), Positives = 62/147 (42%), Gaps = 4/147 (2%)
Frame = +2
Query: 41 LDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEK--IVKQLQHQLNEVQSKAD 214
+D+L + + + +K R + DLR L+HL K E+ + L E ++A
Sbjct: 138 MDKLRQNRLEFQKEREATQELIEDLRKELEHLQMYKLDCERPGRGRSASSGLGEFNARAR 197
Query: 215 EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLS--KIKVSLTTQLEDTKRLADEE 388
E +L+ K+L EN L Q ++ Q+ LS + K Q + A+ +
Sbjct: 198 EV-----ELEHEVKRLKQENYKLRDQNDDLNGQILSLSLYEAKNLFAAQTKAQSLAAEID 252
Query: 389 ARERATLLGKFRNLEHDLDNIREQVEE 469
R L+ + E +R+ +++
Sbjct: 253 TASRDELMEALKEQEEINFRLRQYMDK 279
>AL355378-1|CAI15667.1| 872|Homo sapiens novel protein protein.
Length = 872
Score = 52.8 bits (121), Expect = 1e-06
Identities = 43/233 (18%), Positives = 107/233 (45%), Gaps = 1/233 (0%)
Frame = +2
Query: 23 SDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQ 202
+DM + ++ L+ +K + + L+ + NE+AA+E ++Q Q + ++Q
Sbjct: 230 ADMDSRQTEIKALQQYVQKSKEELQKLEQQLKE--QKILNERAAKE--LEQFQMRNAKLQ 285
Query: 203 SKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLAD 382
+ ++ + L ++ ++E ++ + + +L+KI+ + +L T+
Sbjct: 286 QENEQHSLVCEQLSQENQQKALELKAKEEEVHQMRLDIGKLNKIREQIHKKLHHTEDQKA 345
Query: 383 EEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGV 562
E + + TL + LE +++ ++Q E + + +L R+ N + ++ ++
Sbjct: 346 EVEQHKETLKNQIVGLEREVEASKKQAELDRKAMDELLRERDILNKN--MLKAVNATQKQ 403
Query: 563 ARSEEL-EEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEV 718
+L E+AKR L+ + ++ + + + LEK + R + DL +V
Sbjct: 404 TDLVKLHEQAKRNLEGEIQNYKDEAQKQRKIIFHLEKERDRYINQASDLTQKV 456
Score = 39.5 bits (88), Expect = 0.013
Identities = 46/230 (20%), Positives = 97/230 (42%), Gaps = 1/230 (0%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD 214
+ +D + KA++ E+ +L ++ S Q ++ L EV + D
Sbjct: 104 KMVDSAYDKEQKAKETILALKEEIVNLTKLVEQGSGLSMDQHSNIRDLLRFKEEVTKERD 163
Query: 215 EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEAR 394
+ + L + + + + + R EEAE +SQ + +++ + A E R
Sbjct: 164 QLLSEVVKLRESLAQTTEQQQETERSKEEAEHAISQFQQ-------EIQQRQNEASREFR 216
Query: 395 ERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARS- 571
++ L + + ++ D+D+ + +++ + + +L K E QL K +E A+
Sbjct: 217 KKEKLEKELKQIQADMDSRQTEIKALQQYVQKSKEELQK--LEQQLKEQKILNERAAKEL 274
Query: 572 EELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
E+ + KLQ + E L+Q+ +K + A E E Q+ +D
Sbjct: 275 EQFQMRNAKLQQENEQHSLVCEQLSQE--NQQKALELKAKEEEVHQMRLD 322
>AL162742-5|CAI12110.1| 872|Homo sapiens novel protein protein.
Length = 872
Score = 52.8 bits (121), Expect = 1e-06
Identities = 43/233 (18%), Positives = 107/233 (45%), Gaps = 1/233 (0%)
Frame = +2
Query: 23 SDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQ 202
+DM + ++ L+ +K + + L+ + NE+AA+E ++Q Q + ++Q
Sbjct: 230 ADMDSRQTEIKALQQYVQKSKEELQKLEQQLKE--QKILNERAAKE--LEQFQMRNAKLQ 285
Query: 203 SKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLAD 382
+ ++ + L ++ ++E ++ + + +L+KI+ + +L T+
Sbjct: 286 QENEQHSLVCEQLSQENQQKALELKAKEEEVHQMRLDIGKLNKIREQIHKKLHHTEDQKA 345
Query: 383 EEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGV 562
E + + TL + LE +++ ++Q E + + +L R+ N + ++ ++
Sbjct: 346 EVEQHKETLKNQIVGLEREVEASKKQAELDRKAMDELLRERDILNKN--MLKAVNATQKQ 403
Query: 563 ARSEEL-EEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEV 718
+L E+AKR L+ + ++ + + + LEK + R + DL +V
Sbjct: 404 TDLVKLHEQAKRNLEGEIQNYKDEAQKQRKIIFHLEKERDRYINQASDLTQKV 456
Score = 39.5 bits (88), Expect = 0.013
Identities = 46/230 (20%), Positives = 97/230 (42%), Gaps = 1/230 (0%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD 214
+ +D + KA++ E+ +L ++ S Q ++ L EV + D
Sbjct: 104 KMVDSAYDKEQKAKETILALKEEIVNLTKLVEQGSGLSMDQHSNIRDLLRFKEEVTKERD 163
Query: 215 EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEAR 394
+ + L + + + + + R EEAE +SQ + +++ + A E R
Sbjct: 164 QLLSEVVKLRESLAQTTEQQQETERSKEEAEHAISQFQQ-------EIQQRQNEASREFR 216
Query: 395 ERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARS- 571
++ L + + ++ D+D+ + +++ + + +L K E QL K +E A+
Sbjct: 217 KKEKLEKELKQIQADMDSRQTEIKALQQYVQKSKEELQK--LEQQLKEQKILNERAAKEL 274
Query: 572 EELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
E+ + KLQ + E L+Q+ +K + A E E Q+ +D
Sbjct: 275 EQFQMRNAKLQQENEQHSLVCEQLSQE--NQQKALELKAKEEEVHQMRLD 322
>AK093227-1|BAC04102.1| 550|Homo sapiens protein ( Homo sapiens
cDNA FLJ35908 fis, clone TESTI2009935. ).
Length = 550
Score = 52.8 bits (121), Expect = 1e-06
Identities = 43/233 (18%), Positives = 107/233 (45%), Gaps = 1/233 (0%)
Frame = +2
Query: 23 SDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQ 202
+DM + ++ L+ +K + + L+ + NE+AA+E ++Q Q + ++Q
Sbjct: 230 ADMDSRQTEIKALQQYVQKSKEELQKLEQQLKE--QKILNERAAKE--LEQFQMRNAKLQ 285
Query: 203 SKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLAD 382
+ ++ + L ++ ++E ++ + + +L+KI+ + +L T+
Sbjct: 286 QENEQHSLVCEQLSQENQQKALELKAKEEEVHQMRLDIGKLNKIREQIHKKLHHTEDQKA 345
Query: 383 EEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGV 562
E + + TL + LE +++ ++Q E + + +L R+ N + ++ ++
Sbjct: 346 EVEQHKETLKNQIVGLEREVEASKKQAELDRKAMDELLRERDILNKN--MLKAVNATQKQ 403
Query: 563 ARSEEL-EEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEV 718
+L E+AKR L+ + ++ + + + LEK + R + DL +V
Sbjct: 404 TDLVKLHEQAKRNLEGEIQNYKDEAQKQRKIIFHLEKERDRYINQASDLTQKV 456
Score = 39.5 bits (88), Expect = 0.013
Identities = 46/230 (20%), Positives = 97/230 (42%), Gaps = 1/230 (0%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD 214
+ +D + KA++ E+ +L ++ S Q ++ L EV + D
Sbjct: 104 KMVDSAYDKEQKAKETILALKEEIVNLTKLVEQGSGLSMDQHSNIRDLLRFKEEVTKERD 163
Query: 215 EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEAR 394
+ + L + + + + + R EEAE +SQ + +++ + A E R
Sbjct: 164 QLLSEVVKLRESLAQTTEQQQETERSKEEAEHAISQFQQ-------EIQQRQNEASREFR 216
Query: 395 ERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARS- 571
++ L + + ++ D+D+ + +++ + + +L K E QL K +E A+
Sbjct: 217 KKEKLEKELKQIQADMDSRQTEIKALQQYVQKSKEELQK--LEQQLKEQKILNERAAKEL 274
Query: 572 EELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVD 721
E+ + KLQ + E L+Q+ +K + A E E Q+ +D
Sbjct: 275 EQFQMRNAKLQQENEQHSLVCEQLSQE--NQQKALELKAKEEEVHQMRLD 322
>AJ314646-1|CAC44535.1| 609|Homo sapiens hypothetical protein
protein.
Length = 609
Score = 52.8 bits (121), Expect = 1e-06
Identities = 49/220 (22%), Positives = 97/220 (44%), Gaps = 2/220 (0%)
Frame = +2
Query: 59 LKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRT-LN 235
LK+K ++ Q V++L + + +++ E+ +++ + E K + T +
Sbjct: 336 LKSKLKQENTQLVHRVHELE---EMVKDQETTAEQALEEEARRHREAYGKLEREKATEVE 392
Query: 236 DLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTK-RLADEEARERATLL 412
L+A ++L EN++L + +SQ +L + + ++ +LEDT RL DE +
Sbjct: 393 LLNARVQQLEEENTELRTTVTRLKSQTEKLDEERQRMSDRLEDTSLRLKDE--------M 444
Query: 413 GKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAK 592
++ + L R + ++E E +L L K Q+++ E G RS +
Sbjct: 445 DLYKRMMDKLRQNRLEFQKEREATQELIEDLRKELEHLQMYKLDCERPGRGRSASSGLGE 504
Query: 593 RKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQL 712
+AR E E ++ L Q+ L L ++ L L
Sbjct: 505 FNARAREVELEHEVKRLKQENYKLRDQNDDLNGQILSLSL 544
Score = 35.5 bits (78), Expect = 0.22
Identities = 49/211 (23%), Positives = 89/211 (42%), Gaps = 6/211 (2%)
Frame = +2
Query: 104 VNDLRAGLDHLS----NEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIE 271
+NDL A L +L N K + +QL H N S + + +D+
Sbjct: 256 LNDLEARLKNLKANSPNRKISSTAFGRQLMHSSNFSSSNGSTEDLFRDSIDSC------- 308
Query: 272 NSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNI 451
++D+ ++ E +V++L SLT D K +E + + + + D +
Sbjct: 309 DNDITEKVSFLEKKVTELEND--SLTNG--DLKSKLKQENTQLVHRVHELEEMVKDQETT 364
Query: 452 REQ-VEEEAEGKADLQRQLSKANA-EAQLWRSKYESEGVARSEELEEAKRKLQARLAEAE 625
EQ +EEEA + +L + A E +L AR ++LEE +L+
Sbjct: 365 AEQALEEEARRHREAYGKLEREKATEVELLN--------ARVQQLEEENTELRT------ 410
Query: 626 ETIESLNQKVVALEKTKQRLATEVEDLQLEV 718
T+ L + L++ +QR++ +ED L +
Sbjct: 411 -TVTRLKSQTEKLDEERQRMSDRLEDTSLRL 440
Score = 30.7 bits (66), Expect = 6.2
Identities = 33/147 (22%), Positives = 62/147 (42%), Gaps = 4/147 (2%)
Frame = +2
Query: 41 LDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEK--IVKQLQHQLNEVQSKAD 214
+D+L + + + +K R + DLR L+HL K E+ + L E ++A
Sbjct: 451 MDKLRQNRLEFQKEREATQELIEDLRKELEHLQMYKLDCERPGRGRSASSGLGEFNARAR 510
Query: 215 EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLS--KIKVSLTTQLEDTKRLADEE 388
E +L+ K+L EN L Q ++ Q+ LS + K Q + A+ +
Sbjct: 511 EV-----ELEHEVKRLKQENYKLRDQNDDLNGQILSLSLYEAKNLFAAQTKAQSLAAEID 565
Query: 389 ARERATLLGKFRNLEHDLDNIREQVEE 469
R L+ + E +R+ +++
Sbjct: 566 TASRDELMEALKEQEEINFRLRQYMDK 592
>AB209041-1|BAD92278.1| 303|Homo sapiens TPM1 protein variant
protein.
Length = 303
Score = 52.8 bits (121), Expect = 1e-06
Identities = 53/209 (25%), Positives = 98/209 (46%), Gaps = 5/209 (2%)
Frame = +2
Query: 113 LRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANR----TLNDLDAAKKKLSIENSD 280
L+ LDH + E V L ++ V+ + D A L L+ A+K + + S+
Sbjct: 89 LQRELDHERKLRETAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEK--AADGSE 146
Query: 281 LLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQ 460
++ E+ +Q + K+++ QL++ K +A++ R+ + K +E DL+ E+
Sbjct: 147 RGMKVIESRAQKDE-EKMEIQ-EIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEER 204
Query: 461 VEEEAEGK-ADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIE 637
E +EGK A+L+ +L + ++ E + + EE + L +L EAE E
Sbjct: 205 AEL-SEGKCAELEEELKTVTNNLKSLEAQAEKYS-QKEDRYEEEIKVLSDKLKEAETRAE 262
Query: 638 SLNQKVVALEKTKQRLATEVEDLQLEVDR 724
+ V LEK+ L ++ QLE +R
Sbjct: 263 FAERSVTKLEKSIDDLEDQLYQ-QLEQNR 290
>AB058724-1|BAB47450.1| 609|Homo sapiens KIAA1821 protein protein.
Length = 609
Score = 52.8 bits (121), Expect = 1e-06
Identities = 49/220 (22%), Positives = 97/220 (44%), Gaps = 2/220 (0%)
Frame = +2
Query: 59 LKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRT-LN 235
LK+K ++ Q V++L + + +++ E+ +++ + E K + T +
Sbjct: 336 LKSKLKQENTQLVHRVHELE---EMVKDQETTAEQALEEEARRHREAYGKLEREKATEVE 392
Query: 236 DLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTK-RLADEEARERATLL 412
L+A ++L EN++L + +SQ +L + + ++ +LEDT RL DE +
Sbjct: 393 LLNARVQQLEEENTELRTTVTRLKSQTEKLDEERQRMSDRLEDTSLRLKDE--------M 444
Query: 413 GKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAK 592
++ + L R + ++E E +L L K Q+++ E G RS +
Sbjct: 445 DLYKRMMDKLRQNRLEFQKEREATQELIEDLRKELEHLQMYKLDCERPGRGRSASSGLGE 504
Query: 593 RKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQL 712
+AR E E ++ L Q+ L L ++ L L
Sbjct: 505 FNARAREVELEHEVKRLKQENYKLRDQNDDLNGQILSLSL 544
Score = 35.5 bits (78), Expect = 0.22
Identities = 49/211 (23%), Positives = 89/211 (42%), Gaps = 6/211 (2%)
Frame = +2
Query: 104 VNDLRAGLDHLS----NEKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIE 271
+NDL A L +L N K + +QL H N S + + +D+
Sbjct: 256 LNDLEARLKNLKANSPNRKISSTAFGRQLMHSSNFSSSNGSTEDLFRDSIDSC------- 308
Query: 272 NSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNI 451
++D+ ++ E +V++L SLT D K +E + + + + D +
Sbjct: 309 DNDITEKVSFLEKKVTELEND--SLTNG--DLKSKLKQENTQLVHRVHELEEMVKDQETT 364
Query: 452 REQ-VEEEAEGKADLQRQLSKANA-EAQLWRSKYESEGVARSEELEEAKRKLQARLAEAE 625
EQ +EEEA + +L + A E +L AR ++LEE +L+
Sbjct: 365 AEQALEEEARRHREAYGKLEREKATEVELLN--------ARVQQLEEENTELRT------ 410
Query: 626 ETIESLNQKVVALEKTKQRLATEVEDLQLEV 718
T+ L + L++ +QR++ +ED L +
Sbjct: 411 -TVTRLKSQTEKLDEERQRMSDRLEDTSLRL 440
Score = 30.7 bits (66), Expect = 6.2
Identities = 33/147 (22%), Positives = 62/147 (42%), Gaps = 4/147 (2%)
Frame = +2
Query: 41 LDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEK--IVKQLQHQLNEVQSKAD 214
+D+L + + + +K R + DLR L+HL K E+ + L E ++A
Sbjct: 451 MDKLRQNRLEFQKEREATQELIEDLRKELEHLQMYKLDCERPGRGRSASSGLGEFNARAR 510
Query: 215 EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLS--KIKVSLTTQLEDTKRLADEE 388
E +L+ K+L EN L Q ++ Q+ LS + K Q + A+ +
Sbjct: 511 EV-----ELEHEVKRLKQENYKLRDQNDDLNGQILSLSLYEAKNLFAAQTKAQSLAAEID 565
Query: 389 ARERATLLGKFRNLEHDLDNIREQVEE 469
R L+ + E +R+ +++
Sbjct: 566 TASRDELMEALKEQEEINFRLRQYMDK 592
>X05276-1|CAA28888.1| 248|Homo sapiens protein ( Human mRNA for
fibroblast tropomyosin TM30 (pl). ).
Length = 248
Score = 52.4 bits (120), Expect = 2e-06
Identities = 57/215 (26%), Positives = 90/215 (41%), Gaps = 7/215 (3%)
Frame = +2
Query: 50 LNKLKAKAEKXRA--QYFSEVNDLRAGLDH-LSNEKAAQEKIVKQLQHQLNEVQSKADEA 220
LN L+A K +A Q E D GL L E+ +EK + +Q +E
Sbjct: 4 LNSLEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEEL 63
Query: 221 NRTLNDLDAAKKKLSIENS---DLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEA 391
+R L A +KL + R ++ E++ + + QL++ K +A+E
Sbjct: 64 DRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEAD 123
Query: 392 RERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARS 571
R+ + K LE +L+ E+ E DL+ +L N L + SE +
Sbjct: 124 RKYEEVARKLVILEGELERAEERAEVSELKCGDLEEELK--NVTNNLKSLEAASEKYSEK 181
Query: 572 EE-LEEAKRKLQARLAEAEETIESLNQKVVALEKT 673
E+ EE + L +L EAE E + V LEKT
Sbjct: 182 EDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKT 216
>M19714-1|AAA61226.1| 264|Homo sapiens TPM1 protein.
Length = 264
Score = 52.4 bits (120), Expect = 2e-06
Identities = 53/226 (23%), Positives = 101/226 (44%), Gaps = 5/226 (2%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD 214
++L L K E +Y + D + L+ + E V L ++ V+ + D
Sbjct: 21 DELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELD 80
Query: 215 EANR----TLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLAD 382
A L L+ A+K + + S+ ++ E+ +Q + K+++ QL++ K +A+
Sbjct: 81 RAQERLATALQKLEEAEK--AADESERGMKVIESRAQKDE-EKMEIQ-EIQLKEAKHIAE 136
Query: 383 EEARERATLLGKFRNLEHDLDNIREQVEEEAEGK-ADLQRQLSKANAEAQLWRSKYESEG 559
+ R+ + K +E DL+ E+ E +EGK A+L+ +L + ++ E
Sbjct: 137 DADRKYEEVARKLVIIESDLERAEERAEL-SEGKCAELEEELKTVTNNLKSLEAQAEKYS 195
Query: 560 VARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEV 697
+ + EE + L +L EAE E + V LEK+ L E+
Sbjct: 196 -QKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDEL 240
>M19713-1|AAA61225.1| 284|Homo sapiens TPM1 protein.
Length = 284
Score = 52.4 bits (120), Expect = 2e-06
Identities = 53/226 (23%), Positives = 101/226 (44%), Gaps = 5/226 (2%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD 214
++L L K E +Y + D + L+ + E V L ++ V+ + D
Sbjct: 41 DELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELD 100
Query: 215 EANR----TLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLAD 382
A L L+ A+K + + S+ ++ E+ +Q + K+++ QL++ K +A+
Sbjct: 101 RAQERLATALQKLEEAEK--AADESERGMKVIESRAQKDE-EKMEIQ-EIQLKEAKHIAE 156
Query: 383 EEARERATLLGKFRNLEHDLDNIREQVEEEAEGK-ADLQRQLSKANAEAQLWRSKYESEG 559
+ R+ + K +E DL+ E+ E +EGK A+L+ +L + ++ E
Sbjct: 157 DADRKYEEVARKLVIIESDLERAEERAEL-SEGKCAELEEELKTVTNNLKSLEAQAEKYS 215
Query: 560 VARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEV 697
+ + EE + L +L EAE E + V LEK+ L E+
Sbjct: 216 -QKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDEL 260
>BT019634-1|AAV38440.1| 248|Homo sapiens tropomyosin 4 protein.
Length = 248
Score = 52.4 bits (120), Expect = 2e-06
Identities = 57/215 (26%), Positives = 90/215 (41%), Gaps = 7/215 (3%)
Frame = +2
Query: 50 LNKLKAKAEKXRA--QYFSEVNDLRAGLDH-LSNEKAAQEKIVKQLQHQLNEVQSKADEA 220
LN L+A K +A Q E D GL L E+ +EK + +Q +E
Sbjct: 4 LNSLEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEEL 63
Query: 221 NRTLNDLDAAKKKLSIENS---DLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEA 391
+R L A +KL + R ++ E++ + + QL++ K +A+E
Sbjct: 64 DRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEAD 123
Query: 392 RERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARS 571
R+ + K LE +L+ E+ E DL+ +L N L + SE +
Sbjct: 124 RKYEEVARKLVILEGELERAEERAEVSELKCGDLEEELK--NVTNNLKSLEAASEKYSEK 181
Query: 572 EE-LEEAKRKLQARLAEAEETIESLNQKVVALEKT 673
E+ EE + L +L EAE E + V LEKT
Sbjct: 182 EDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKT 216
>BC067225-1|AAH67225.1| 248|Homo sapiens tropomyosin 4 protein.
Length = 248
Score = 52.4 bits (120), Expect = 2e-06
Identities = 57/215 (26%), Positives = 90/215 (41%), Gaps = 7/215 (3%)
Frame = +2
Query: 50 LNKLKAKAEKXRA--QYFSEVNDLRAGLDH-LSNEKAAQEKIVKQLQHQLNEVQSKADEA 220
LN L+A K +A Q E D GL L E+ +EK + +Q +E
Sbjct: 4 LNSLEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEEL 63
Query: 221 NRTLNDLDAAKKKLSIENS---DLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEA 391
+R L A +KL + R ++ E++ + + QL++ K +A+E
Sbjct: 64 DRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEAD 123
Query: 392 RERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARS 571
R+ + K LE +L+ E+ E DL+ +L N L + SE +
Sbjct: 124 RKYEEVARKLVILEGELERAEERAEVSELKCGDLEEELK--NVTNNLKSLEAASEKYSEK 181
Query: 572 EE-LEEAKRKLQARLAEAEETIESLNQKVVALEKT 673
E+ EE + L +L EAE E + V LEKT
Sbjct: 182 EDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKT 216
>BC067085-1|AAH67085.1| 615|Homo sapiens HIP1R protein protein.
Length = 615
Score = 52.4 bits (120), Expect = 2e-06
Identities = 55/232 (23%), Positives = 107/232 (46%), Gaps = 11/232 (4%)
Frame = +2
Query: 47 QLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANR 226
+L K+K +A++ AQ S+VN L L+ +K +QL+H+L ++++ E R
Sbjct: 369 ELEKIKLEAQRYIAQLKSQVNALEGELEEQRKQKQKALVDNEQLRHELAQLRAAQLEGER 428
Query: 227 TLNDLDAAKKKLSIENSDLLRQLEEAESQV----SQLSKIKVSLTTQLEDTKRLADEEAR 394
+ + A++K S + +L+E S++ ++L + QL T++ +E AR
Sbjct: 429 SQGLREEAERKASATEA-RYNKLKEKHSELVHVHAELLRKNADTAKQLTVTQQSQEEVAR 487
Query: 395 ERATLLGKF----RNLEHDLDNIREQVEE---EAEGKADLQRQLSKANAEAQLWRSKYES 553
+ L + R E L+ +Q+E+ E E KA + +A + + +S+ S
Sbjct: 488 VKEQLAFQVEQVKRESELKLEEKSDQLEKLKRELEAKAGELARAQEALSHTEQSKSELSS 547
Query: 554 EGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQ 709
S E + ++ R A+ + + AL + +QR + E +LQ
Sbjct: 548 RLDTLSAEKDALSGAVRQREADLLAAQSLVRETEAALSREQQRSSQEQGELQ 599
Score = 31.9 bits (69), Expect = 2.7
Identities = 28/94 (29%), Positives = 47/94 (50%), Gaps = 2/94 (2%)
Frame = +2
Query: 425 NLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQ 604
+++ D D E ++ E E L+ +L K EAQ + ++ +S+ A ELEE +++ Q
Sbjct: 347 SVKDDRDLQIESLKREVEM---LRSELEKIKLEAQRYIAQLKSQVNALEGELEEQRKQKQ 403
Query: 605 ARLAEAEETIESLNQ-KVVALE-KTKQRLATEVE 700
L + E+ L Q + LE + Q L E E
Sbjct: 404 KALVDNEQLRHELAQLRAAQLEGERSQGLREEAE 437
>BC037576-1|AAH37576.1| 248|Homo sapiens tropomyosin 4 protein.
Length = 248
Score = 52.4 bits (120), Expect = 2e-06
Identities = 57/215 (26%), Positives = 90/215 (41%), Gaps = 7/215 (3%)
Frame = +2
Query: 50 LNKLKAKAEKXRA--QYFSEVNDLRAGLDH-LSNEKAAQEKIVKQLQHQLNEVQSKADEA 220
LN L+A K +A Q E D GL L E+ +EK + +Q +E
Sbjct: 4 LNSLEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEEL 63
Query: 221 NRTLNDLDAAKKKLSIENS---DLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEA 391
+R L A +KL + R ++ E++ + + QL++ K +A+E
Sbjct: 64 DRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEAD 123
Query: 392 RERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARS 571
R+ + K LE +L+ E+ E DL+ +L N L + SE +
Sbjct: 124 RKYEEVARKLVILEGELERAEERAEVSELKCGDLEEELK--NVTNNLKSLEAASEKYSEK 181
Query: 572 EE-LEEAKRKLQARLAEAEETIESLNQKVVALEKT 673
E+ EE + L +L EAE E + V LEKT
Sbjct: 182 EDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKT 216
>AK131384-1|BAD18535.1| 326|Homo sapiens protein ( Homo sapiens
cDNA FLJ16459 fis, clone BRCAN2002473, moderately
similar to Tropomyosin, fibroblast isoform 2. ).
Length = 326
Score = 52.4 bits (120), Expect = 2e-06
Identities = 54/236 (22%), Positives = 105/236 (44%), Gaps = 5/236 (2%)
Frame = +2
Query: 5 SAGRFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQH 184
+A + + ++L L K E +Y + D + L+ + E V L
Sbjct: 73 AAEEAAAKLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNR 132
Query: 185 QLNEVQSKADEANR----TLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTT 352
++ V+ + D A L L+ A+K + + S+ ++ E+ +Q + K+++
Sbjct: 133 RIQLVEEELDRAQERLATALQKLEEAEK--AADESERGMKVIESRAQKDE-EKMEIQ-EI 188
Query: 353 QLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGK-ADLQRQLSKANAEAQ 529
QL++ K +A++ R+ + K +E DL+ E+ E +EGK A+L+ +L +
Sbjct: 189 QLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAEL-SEGKCAELEEELKTVTNNLK 247
Query: 530 LWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEV 697
++ E + + EE + L +L EAE E + V LEK+ L +V
Sbjct: 248 SLEAQAEKYS-QKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKV 302
>AF310722-1|AAK17926.1| 320|Homo sapiens tropomyosin 4-anaplastic
lymphoma kinase fusion protein protein.
Length = 320
Score = 52.4 bits (120), Expect = 2e-06
Identities = 57/215 (26%), Positives = 90/215 (41%), Gaps = 7/215 (3%)
Frame = +2
Query: 50 LNKLKAKAEKXRA--QYFSEVNDLRAGLDH-LSNEKAAQEKIVKQLQHQLNEVQSKADEA 220
LN L+A K +A Q E D GL L E+ +EK + +Q +E
Sbjct: 4 LNSLEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEEL 63
Query: 221 NRTLNDLDAAKKKLSIENS---DLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEA 391
+R L A +KL + R ++ E++ + + QL++ K +A+E
Sbjct: 64 DRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEAD 123
Query: 392 RERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARS 571
R+ + K LE +L+ E+ E DL+ +L N L + SE +
Sbjct: 124 RKYEEVARKLVILEGELERAEERAEVSELKCGDLEEELK--NVTNNLKSLEAASEKYSEK 181
Query: 572 EE-LEEAKRKLQARLAEAEETIESLNQKVVALEKT 673
E+ EE + L +L EAE E + V LEKT
Sbjct: 182 EDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKT 216
>AF186109-1|AAG17014.1| 237|Homo sapiens TPM4-ALK fusion
oncoprotein type 2 protein.
Length = 237
Score = 52.4 bits (120), Expect = 2e-06
Identities = 57/215 (26%), Positives = 90/215 (41%), Gaps = 7/215 (3%)
Frame = +2
Query: 50 LNKLKAKAEKXRA--QYFSEVNDLRAGLDH-LSNEKAAQEKIVKQLQHQLNEVQSKADEA 220
LN L+A K +A Q E D GL L E+ +EK + +Q +E
Sbjct: 4 LNSLEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEEL 63
Query: 221 NRTLNDLDAAKKKLSIENS---DLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEA 391
+R L A +KL + R ++ E++ + + QL++ K +A+E
Sbjct: 64 DRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEAD 123
Query: 392 RERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARS 571
R+ + K LE +L+ E+ E DL+ +L N L + SE +
Sbjct: 124 RKYEEVARKLVILEGELERAEERAEVSELKCGDLEEELK--NVTNNLKSLEAASEKYSEK 181
Query: 572 EE-LEEAKRKLQARLAEAEETIESLNQKVVALEKT 673
E+ EE + L +L EAE E + V LEKT
Sbjct: 182 EDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKT 216
>AB014555-1|BAA31630.1| 1083|Homo sapiens KIAA0655 protein protein.
Length = 1083
Score = 52.4 bits (120), Expect = 2e-06
Identities = 55/232 (23%), Positives = 107/232 (46%), Gaps = 11/232 (4%)
Frame = +2
Query: 47 QLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANR 226
+L K+K +A++ AQ S+VN L L+ +K +QL+H+L ++++ E R
Sbjct: 384 ELEKIKLEAQRYIAQLKSQVNALEGELEEQRKQKQKALVDNEQLRHELAQLRAAQLEGER 443
Query: 227 TLNDLDAAKKKLSIENSDLLRQLEEAESQV----SQLSKIKVSLTTQLEDTKRLADEEAR 394
+ + A++K S + +L+E S++ ++L + QL T++ +E AR
Sbjct: 444 SQGLREEAERKASATEA-RYNKLKEKHSELVHVHAELLRKNADTAKQLTVTQQSQEEVAR 502
Query: 395 ERATLLGKF----RNLEHDLDNIREQVEE---EAEGKADLQRQLSKANAEAQLWRSKYES 553
+ L + R E L+ +Q+E+ E E KA + +A + + +S+ S
Sbjct: 503 VKEQLAFQVEQVKRESELKLEEKSDQLEKLKRELEAKAGELARAQEALSHTEQSKSELSS 562
Query: 554 EGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQ 709
S E + ++ R A+ + + AL + +QR + E +LQ
Sbjct: 563 RLDTLSAEKDALSGAVRQREADLLAAQSLVRETEAALSREQQRSSQEQGELQ 614
Score = 31.9 bits (69), Expect = 2.7
Identities = 28/94 (29%), Positives = 47/94 (50%), Gaps = 2/94 (2%)
Frame = +2
Query: 425 NLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQ 604
+++ D D E ++ E E L+ +L K EAQ + ++ +S+ A ELEE +++ Q
Sbjct: 362 SVKDDRDLQIESLKREVEM---LRSELEKIKLEAQRYIAQLKSQVNALEGELEEQRKQKQ 418
Query: 605 ARLAEAEETIESLNQ-KVVALE-KTKQRLATEVE 700
L + E+ L Q + LE + Q L E E
Sbjct: 419 KALVDNEQLRHELAQLRAAQLEGERSQGLREEAE 452
>AB013384-1|BAA33713.1| 890|Homo sapiens HIP1R protein.
Length = 890
Score = 52.4 bits (120), Expect = 2e-06
Identities = 55/232 (23%), Positives = 107/232 (46%), Gaps = 11/232 (4%)
Frame = +2
Query: 47 QLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANR 226
+L K+K +A++ AQ S+VN L L+ +K +QL+H+L ++++ E R
Sbjct: 191 ELEKIKLEAQRYIAQLKSQVNALEGELEEQRKQKQKALVDNEQLRHELAQLRAAQLEGER 250
Query: 227 TLNDLDAAKKKLSIENSDLLRQLEEAESQV----SQLSKIKVSLTTQLEDTKRLADEEAR 394
+ + A++K S + +L+E S++ ++L + QL T++ +E AR
Sbjct: 251 SQGLREEAERKASATEA-RYNKLKEKHSELVHVHAELLRKNADTAKQLTVTQQSQEEVAR 309
Query: 395 ERATLLGKF----RNLEHDLDNIREQVEE---EAEGKADLQRQLSKANAEAQLWRSKYES 553
+ L + R E L+ +Q+E+ E E KA + +A + + +S+ S
Sbjct: 310 VKEQLAFQVEQVKRESELKLEEKSDQLEKLKRELEAKAGELARAQEALSHTEQSKSELSS 369
Query: 554 EGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQ 709
S E + ++ R A+ + + AL + +QR + E +LQ
Sbjct: 370 RLDTLSAEKDALSGAVRQREADLLAAQSLVRETEAALSREQQRSSQEQGELQ 421
Score = 31.9 bits (69), Expect = 2.7
Identities = 28/94 (29%), Positives = 47/94 (50%), Gaps = 2/94 (2%)
Frame = +2
Query: 425 NLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQ 604
+++ D D E ++ E E L+ +L K EAQ + ++ +S+ A ELEE +++ Q
Sbjct: 169 SVKDDRDLQIESLKREVEM---LRSELEKIKLEAQRYIAQLKSQVNALEGELEEQRKQKQ 225
Query: 605 ARLAEAEETIESLNQ-KVVALE-KTKQRLATEVE 700
L + E+ L Q + LE + Q L E E
Sbjct: 226 KALVDNEQLRHELAQLRAAQLEGERSQGLREEAE 259
>X06825-1|CAA29971.1| 284|Homo sapiens protein ( Human mRNA for
skeletal beta-tropomyosin. ).
Length = 284
Score = 52.0 bits (119), Expect = 2e-06
Identities = 47/222 (21%), Positives = 92/222 (41%), Gaps = 1/222 (0%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSE-VNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKA 211
E+ Q + K K + + +SE V + + L+ + E V L ++ V+ +
Sbjct: 40 EEEQQALQKKLKGTEDEVEKYSESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEEL 99
Query: 212 DEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEA 391
D A L ++ + R ++ E++ + + QL++ K +A++
Sbjct: 100 DRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSD 159
Query: 392 RERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARS 571
R+ + K LE +L+ E+ E DL+ +L + ++ + +
Sbjct: 160 RKYEEVARKLVILEGELERSEERAEVAESKCGDLEEELKIVTNNLKSLEAQADKYST-KE 218
Query: 572 EELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEV 697
++ EE + L+ +L EAE E + V LEKT L EV
Sbjct: 219 DKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEDEV 260
>U72849-1|AAD00186.1| 2033|Homo sapiens envoplakin protein.
Length = 2033
Score = 52.0 bits (119), Expect = 2e-06
Identities = 63/237 (26%), Positives = 110/237 (46%), Gaps = 14/237 (5%)
Frame = +2
Query: 8 AGRFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAG--LDHLSNEKAAQEKIVKQLQ 181
AGR + QL++ K A+ + S++ LR L+ L ++ + QL+
Sbjct: 910 AGRESEALKAQLEEERKRVARVQHELEAQRSQLLQLRTQRPLERLEEKEVVEFYRDPQLE 969
Query: 182 HQLNEVQSKADEANRTLNDLDA-----AKKKLSIENSDLLRQLEEAESQVSQLSKIKV-- 340
L+ V+++ +E + L A A+K + +E+ Q +V+Q+ +
Sbjct: 970 GSLSRVKAQVEEEGKRRAGLQADLEVAAQKVVQLESKRKTMQPHLLTKEVTQVERDPGLD 1029
Query: 341 SLTTQLE-DTKRLADEEARERATLLGKFRNL----EHDLDNIREQVEEEAEGKADLQRQL 505
S QL ++L E+A A L G + L + ++D ++E+V + K + ++
Sbjct: 1030 SQAAQLRIQIQQLRGEDAVISARLEGLKKELLALEKREVD-VKEKVVVKEVVKVEKNLEM 1088
Query: 506 SKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTK 676
KA AQ R + E E AR ++ EEA KLQAR+ + E I S+ KV+ E K
Sbjct: 1089 VKA---AQALRLQME-EDAARRKQAEEAVAKLQARIEDLERAISSVEPKVIVKEVKK 1141
>U53786-1|AAC64662.1| 2033|Homo sapiens envoplakin protein.
Length = 2033
Score = 52.0 bits (119), Expect = 2e-06
Identities = 63/237 (26%), Positives = 110/237 (46%), Gaps = 14/237 (5%)
Frame = +2
Query: 8 AGRFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAG--LDHLSNEKAAQEKIVKQLQ 181
AGR + QL++ K A+ + S++ LR L+ L ++ + QL+
Sbjct: 910 AGRESEALKAQLEEERKRVARVQHELEAQRSQLLQLRTQRPLERLEEKEVVEFYRDPQLE 969
Query: 182 HQLNEVQSKADEANRTLNDLDA-----AKKKLSIENSDLLRQLEEAESQVSQLSKIKV-- 340
L+ V+++ +E + L A A+K + +E+ Q +V+Q+ +
Sbjct: 970 GSLSRVKAQVEEEGKRRAGLQADLEVAAQKVVQLESKRKTMQPHLLTKEVTQVERDPGLD 1029
Query: 341 SLTTQLE-DTKRLADEEARERATLLGKFRNL----EHDLDNIREQVEEEAEGKADLQRQL 505
S QL ++L E+A A L G + L + ++D ++E+V + K + ++
Sbjct: 1030 SQAAQLRIQIQQLRGEDAVISARLEGLKKELLALEKREVD-VKEKVVVKEVVKVEKNLEM 1088
Query: 506 SKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTK 676
KA AQ R + E E AR ++ EEA KLQAR+ + E I S+ KV+ E K
Sbjct: 1089 VKA---AQALRLQME-EDAARRKQAEEAVAKLQARIEDLERAISSVEPKVIVKEVKK 1141
>BC126105-1|AAI26106.1| 2033|Homo sapiens envoplakin protein.
Length = 2033
Score = 52.0 bits (119), Expect = 2e-06
Identities = 63/237 (26%), Positives = 110/237 (46%), Gaps = 14/237 (5%)
Frame = +2
Query: 8 AGRFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAG--LDHLSNEKAAQEKIVKQLQ 181
AGR + QL++ K A+ + S++ LR L+ L ++ + QL+
Sbjct: 910 AGRESEALKAQLEEERKRVARVQHELEAQRSQLLQLRTQRPLERLEEKEVVEFYRDPQLE 969
Query: 182 HQLNEVQSKADEANRTLNDLDA-----AKKKLSIENSDLLRQLEEAESQVSQLSKIKV-- 340
L+ V+++ +E + L A A+K + +E+ Q +V+Q+ +
Sbjct: 970 GSLSRVKAQVEEEGKRRAGLQADLEVAAQKVVQLESKRKTMQPHLLTKEVTQVERDPGLD 1029
Query: 341 SLTTQLE-DTKRLADEEARERATLLGKFRNL----EHDLDNIREQVEEEAEGKADLQRQL 505
S QL ++L E+A A L G + L + ++D ++E+V + K + ++
Sbjct: 1030 SQAAQLRIQIQQLRGEDAVISARLEGLKKELLALEKREVD-VKEKVVVKEVVKVEKNLEM 1088
Query: 506 SKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTK 676
KA AQ R + E E AR ++ EEA KLQAR+ + E I S+ KV+ E K
Sbjct: 1089 VKA---AQALRLQME-EDAARRKQAEEAVAKLQARIEDLERAISSVEPKVIVKEVKK 1141
>BC126103-1|AAI26104.1| 2033|Homo sapiens envoplakin protein.
Length = 2033
Score = 52.0 bits (119), Expect = 2e-06
Identities = 63/237 (26%), Positives = 110/237 (46%), Gaps = 14/237 (5%)
Frame = +2
Query: 8 AGRFVSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAG--LDHLSNEKAAQEKIVKQLQ 181
AGR + QL++ K A+ + S++ LR L+ L ++ + QL+
Sbjct: 910 AGRESEALKAQLEEERKRVARVQHELEAQRSQLLQLRTQRPLERLEEKEVVEFYRDPQLE 969
Query: 182 HQLNEVQSKADEANRTLNDLDA-----AKKKLSIENSDLLRQLEEAESQVSQLSKIKV-- 340
L+ V+++ +E + L A A+K + +E+ Q +V+Q+ +
Sbjct: 970 GSLSRVKAQVEEEGKRRAGLQADLEVAAQKVVQLESKRKTMQPHLLTKEVTQVERDPGLD 1029
Query: 341 SLTTQLE-DTKRLADEEARERATLLGKFRNL----EHDLDNIREQVEEEAEGKADLQRQL 505
S QL ++L E+A A L G + L + ++D ++E+V + K + ++
Sbjct: 1030 SQAAQLRIQIQQLRGEDAVISARLEGLKKELLALEKREVD-VKEKVVVKEVVKVEKNLEM 1088
Query: 506 SKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTK 676
KA AQ R + E E AR ++ EEA KLQAR+ + E I S+ KV+ E K
Sbjct: 1089 VKA---AQALRLQME-EDAARRKQAEEAVAKLQARIEDLERAISSVEPKVIVKEVKK 1141
>BC002827-1|AAH02827.1| 248|Homo sapiens tropomyosin 4 protein.
Length = 248
Score = 52.0 bits (119), Expect = 2e-06
Identities = 57/215 (26%), Positives = 90/215 (41%), Gaps = 7/215 (3%)
Frame = +2
Query: 50 LNKLKAKAEKXRA--QYFSEVNDLRAGLDH-LSNEKAAQEKIVKQLQHQLNEVQSKADEA 220
LN L+A K +A Q E D GL L E+ +EK + +Q +E
Sbjct: 4 LNSLEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLFEEEL 63
Query: 221 NRTLNDLDAAKKKLSIENS---DLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEA 391
+R L A +KL + R ++ E++ + + QL++ K +A+E
Sbjct: 64 DRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEAD 123
Query: 392 RERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARS 571
R+ + K LE +L+ E+ E DL+ +L N L + SE +
Sbjct: 124 RKYEEVARKLVILEGELERAEERAEVSELKCGDLEEELK--NVTNNLKSLEAASEKYSEK 181
Query: 572 EE-LEEAKRKLQARLAEAEETIESLNQKVVALEKT 673
E+ EE + L +L EAE E + V LEKT
Sbjct: 182 EDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKT 216
>AL133410-4|CAI10977.1| 284|Homo sapiens tropomyosin 2 (beta)
protein.
Length = 284
Score = 52.0 bits (119), Expect = 2e-06
Identities = 47/222 (21%), Positives = 92/222 (41%), Gaps = 1/222 (0%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSE-VNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKA 211
E+ Q + K K + + +SE V + + L+ + E V L ++ V+ +
Sbjct: 40 EEEQQALQKKLKGTEDEVEKYSESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEEL 99
Query: 212 DEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEA 391
D A L ++ + R ++ E++ + + QL++ K +A++
Sbjct: 100 DRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSD 159
Query: 392 RERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARS 571
R+ + K LE +L+ E+ E DL+ +L + ++ + +
Sbjct: 160 RKYEEVARKLVILEGELERSEERAEVAESKCGDLEEELKIVTNNLKSLEAQADKYST-KE 218
Query: 572 EELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEV 697
++ EE + L+ +L EAE E + V LEKT L EV
Sbjct: 219 DKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEDEV 260
>AK023385-1|BAB14554.1| 284|Homo sapiens protein ( Homo sapiens
cDNA FLJ13323 fis, clone OVARC1001731, highly similar to
TROPOMYOSIN ALPHA CHAIN, FIBROBLAST ISOFORM F2. ).
Length = 284
Score = 52.0 bits (119), Expect = 2e-06
Identities = 54/218 (24%), Positives = 93/218 (42%), Gaps = 5/218 (2%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD 214
E+L L K E +Y ++ D + L+ + + E V L ++ V+ + D
Sbjct: 41 EELTHLQKKLKGTEDELDKYSEDLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELD 100
Query: 215 EANR----TLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLAD 382
A L L+ A+K E+ ++ +E + + +I+ QL++ K +A+
Sbjct: 101 RAQERLATALQKLEEAEKAAD-ESERGMKVIENRAMKDEEKMEIQ---EMQLKEAKHIAE 156
Query: 383 EEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGV 562
E R+ + K LE +L+ E+ E DL+ +L N L + SE
Sbjct: 157 EADRKYEEVARKLVILEGELERAEERAEVSELKCGDLEEELK--NVTNNLKSLEAASEKY 214
Query: 563 ARSEE-LEEAKRKLQARLAEAEETIESLNQKVVALEKT 673
+ E+ EE + L +L EAE E + V LEKT
Sbjct: 215 SEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKT 252
>AF039690-1|AAC18039.1| 414|Homo sapiens antigen NY-CO-8 protein.
Length = 414
Score = 52.0 bits (119), Expect = 2e-06
Identities = 56/223 (25%), Positives = 98/223 (43%)
Frame = +2
Query: 56 KLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANRTLN 235
+L+A+ EK + S +N L L++ + K+ ++++QLN+ + DEA +
Sbjct: 197 QLEAQVEKVTKEKISAINQLEEIQSQLASREMDVTKVCGEMRYQLNKTNMEKDEAEKEHR 256
Query: 236 DLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARERATLLG 415
+ A N DL + +E E +L + K L Q + LA EE LLG
Sbjct: 257 EFRAK------TNRDLEIKDQEIEKLRIELDESKQHL-EQEQQKAALAREECLRLTELLG 309
Query: 416 KFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSEELEEAKR 595
+ EH L R ++ + ++ K +L K Q + E + V E K+
Sbjct: 310 E---SEHQLHLTRSEIAQLSQEKRYTYDKLGK----LQRRNEELEEQCVQHGRVHETMKQ 362
Query: 596 KLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
RL + ++ ++ Q++V L + +L E + L EVDR
Sbjct: 363 ----RLRQLDKHSQATAQQLVQLLSKQNQLLLERQSLSEEVDR 401
Score = 41.1 bits (92), Expect = 0.004
Identities = 43/231 (18%), Positives = 101/231 (43%), Gaps = 1/231 (0%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD 214
EQ+ Q+ ++ +A + + + + LR L+ + E++ K+L Q + +A
Sbjct: 118 EQVKQVLQISEEANFEKTKALIQCDQLRKELERQA------ERLEKELASQQ---EKRAI 168
Query: 215 EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEAR 394
E + ++ ++ + + L + + + E+QV +++K K+S QLE+ +
Sbjct: 169 EKDMMKKEITKEREYMGSKMLILSQNIAQLEAQVEKVTKEKISAINQLEEIQSQLASREM 228
Query: 395 ERATLLGKFRNLEHDLDNIREQVEEE-AEGKADLQRQLSKANAEAQLWRSKYESEGVARS 571
+ + G+ R + + +++ E+E E +A R L + E + R + +
Sbjct: 229 DVTKVCGEMRYQLNKTNMEKDEAEKEHREFRAKTNRDLEIKDQEIEKLRIELDES----K 284
Query: 572 EELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
+ LE+ ++K E E L + L T+ +A ++ + D+
Sbjct: 285 QHLEQEQQKAALAREECLRLTELLGESEHQLHLTRSEIAQLSQEKRYTYDK 335
>Z11583-1|CAA77669.1| 2115|Homo sapiens NuMA protein protein.
Length = 2115
Score = 51.6 bits (118), Expect = 3e-06
Identities = 54/248 (21%), Positives = 106/248 (42%), Gaps = 18/248 (7%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD 214
E D +A++ +A+ +V +L+A ++ E+ + V +L+ QL Q KA
Sbjct: 629 EARDSAQTSVTQAQREKAELSRKVEELQACVETARQEQHEAQAQVAELELQLRSEQQKAT 688
Query: 215 EANRTLNDLD-------AAKKKLSIENSDLLRQ-------LEEAESQVSQLSKIKVSLTT 352
E R + D A K+ L + L + LEE + +S+L SL
Sbjct: 689 EKERVAQEKDQLQEQLQALKESLKVTKGSLEEEKRRAADALEEQQRCISELKAETRSLVE 748
Query: 353 QLEDTKRLADEEARERATLLGKFRNL----EHDLDNIREQVEEEAEGKADLQRQLSKANA 520
Q + ++ +EE R L + + L + + + +R ++ E + + + +
Sbjct: 749 QHKRERKELEEERAGRKGLEARLQQLGEAHQAETEVLRRELAEAMAAQHTAESECEQLVK 808
Query: 521 EAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVE 700
E WR +YE ++ EE + Q +L +E E Q+ L++ K+++A
Sbjct: 809 EVAAWRERYED---SQQEEAQYG-AMFQEQLMTLKEECEKARQE---LQEAKEKVAGIES 861
Query: 701 DLQLEVDR 724
+L++ R
Sbjct: 862 HSELQISR 869
Score = 44.0 bits (99), Expect = 6e-04
Identities = 64/257 (24%), Positives = 110/257 (42%), Gaps = 20/257 (7%)
Frame = +2
Query: 14 RFVSDMGEQLDQLN----KLKAKAEKXRAQYFSEVNDL-----RAGLDHLSNEKAAQEKI 166
R MG +L++L + + + ++ R Q EV L RA D L+ EKAA+ ++
Sbjct: 972 REAEQMGNELERLRAALMESQGQQQEERGQQEREVARLTQERGRAQAD-LALEKAARAEL 1030
Query: 167 VKQLQHQLNE-------VQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQL 325
+LQ+ LNE +Q A D KL + +++LEE V QL
Sbjct: 1031 EMRLQNALNEQRVEFATLQEALAHALTEKEGKDQELAKLRGLEAAQIKELEELRQTVKQL 1090
Query: 326 SKIKVSLTTQLEDTKRLADEEARERATLLG-KFRNLEHDLDNIREQVEEEAEGKADLQRQ 502
K +++ + + A EA R G K L ++ + +Q +++ E L+R
Sbjct: 1091 -KEQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALRAEVSKLEQQCQKQQEQADSLERS 1149
Query: 503 LSKANAEAQLWRSKYESEGVARSEELEEAKRKL---QARLAEAEETIESLNQKVVALEKT 673
L A R++ +S +LEE ++L Q+ LA A+ + + KV K
Sbjct: 1150 LEAERAS----RAERDSALETLQGQLEEKAQELGHSQSALASAQRELAAFRTKVQDHSKA 1205
Query: 674 KQRLATEVEDLQLEVDR 724
+ +V + E +R
Sbjct: 1206 EDEWKAQVARGRQEAER 1222
Score = 42.7 bits (96), Expect = 0.001
Identities = 46/223 (20%), Positives = 91/223 (40%), Gaps = 4/223 (1%)
Frame = +2
Query: 20 VSDMGEQLDQLNK-LKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNE 196
V + L Q + LK AEK A L + ++ +KQL+ E
Sbjct: 553 VEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERDAALKQLEALEKE 612
Query: 197 VQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRL 376
+K L+ +++L + N + A++ V+Q + K L+ ++E+ +
Sbjct: 613 KAAK----------LEILQQQLQVAN----EARDSAQTSVTQAQREKAELSRKVEELQAC 658
Query: 377 ADEEARERATLLGKFRNLEHDLDNIREQVEEE---AEGKADLQRQLSKANAEAQLWRSKY 547
+ +E+ + LE L + +++ E+ A+ K LQ QL ++ +
Sbjct: 659 VETARQEQHEAQAQVAELELQLRSEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGSL 718
Query: 548 ESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTK 676
E E ++ LEE +R + AE +E ++ LE+ +
Sbjct: 719 EEEKRRAADALEEQQRCISELKAETRSLVEQHKRERKELEEER 761
Score = 40.3 bits (90), Expect = 0.008
Identities = 49/237 (20%), Positives = 106/237 (44%), Gaps = 10/237 (4%)
Frame = +2
Query: 44 DQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEAN 223
++L + K A RA+ +L L L + A QE+ +QL+ + +
Sbjct: 1383 EELEQSKQAAGGLRAELLRAQREL-GELIPLRQKVAEQERTAQQLRAEKASYAEQLSMLK 1441
Query: 224 RTLNDLDAAKKKLSIENSDLLRQ-----LEEA-ESQVSQLSKIKVSLTTQLEDTKRLADE 385
+ L + L E ++L RQ L++A E V +L+ ++ T+L + +R A
Sbjct: 1442 KAHGLLAEENRGLG-ERANLGRQFLEVELDQAREKYVQELAAVRADAETRLAEVQREAQS 1500
Query: 386 EARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVA 565
ARE + K+ + + R++ +EE + QL E Q + + S+ +A
Sbjct: 1501 TARELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQLEVFQRE-QTKQVEELSKKLA 1559
Query: 566 RSEELEEAKRK----LQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
S++ + +++ +QA+ E+++ + L ++ L+ + E +L++++
Sbjct: 1560 DSDQASKVQQQKLKAVQAQGGESQQEAQRLQAQLNELQAQLSQKEQAAEHYKLQMEK 1616
>X82834-1|CAA58041.1| 2185|Homo sapiens 256 kD golgin protein.
Length = 2185
Score = 51.6 bits (118), Expect = 3e-06
Identities = 46/203 (22%), Positives = 92/203 (45%), Gaps = 15/203 (7%)
Frame = +2
Query: 143 EKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQ 322
E K ++ LQ ++ ++ T+ L+ E L QL+E ++ +
Sbjct: 273 EDGTSVKTLETLQQRVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQLDERLQELEK 332
Query: 323 LSKI----KVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKAD 490
+ + K L TQL D K L ++ +++ ++ + + H E +E + E A
Sbjct: 333 IKDLHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMH------ETLEMKEEEIAQ 386
Query: 491 LQRQLSKANAEAQLWRSKYESEGVARSEELEEA----------KRKLQARLAEAEETIES 640
L+ ++ + + + R + E A EELE+A +RKL+A + E +TIE
Sbjct: 387 LRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEK 446
Query: 641 LNQKV-VALEKTKQRLATEVEDL 706
+++ ++L++ R+ EV D+
Sbjct: 447 TSEEERISLQQELSRVKQEVVDV 469
Score = 48.0 bits (109), Expect = 4e-05
Identities = 52/244 (21%), Positives = 108/244 (44%), Gaps = 17/244 (6%)
Frame = +2
Query: 44 DQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIV--KQLQHQLNEVQSKADE 217
+Q+ KL+ EK A+ + +L L E Q K+ K L Q K +
Sbjct: 476 EQIAKLQKLHEKELAR---KEQELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKEQQ 532
Query: 218 ANRTLNDLDAAKKKLSIENSDLLRQLE-EAESQVSQLSKIKVSLTTQLEDTKR------- 373
+ L +L+ KK + E+ + LR L+ EAE+ +++ +++ SL L++ K
Sbjct: 533 ESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAV 592
Query: 374 -LADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYE 550
L E+ + + + +L++++ Q + K + +Q + E + + E
Sbjct: 593 HLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQE 652
Query: 551 SEGVARSEEL------EEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQL 712
E + + +E+ EE K +L + +ESL+ ++ + K + +L E+ L+
Sbjct: 653 KETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKD 712
Query: 713 EVDR 724
+ D+
Sbjct: 713 QTDK 716
Score = 47.6 bits (108), Expect = 5e-05
Identities = 39/225 (17%), Positives = 100/225 (44%)
Frame = +2
Query: 32 GEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKA 211
G Q ++ ++ + + + +N + + L +K + KQL ++Q+
Sbjct: 1328 GNQQQAASEKESCITQLKKELSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSI 1387
Query: 212 DEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEA 391
+ + + + +K+ E +LL Q+++ +V LSK K+S Q++D E
Sbjct: 1388 SLSEKEAA-ISSLRKQYDEEKCELLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWK 1446
Query: 392 RERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARS 571
++ + +F ++ + ++ Q+E +++ + Q++ E +++
Sbjct: 1447 KKAQS---RFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFD----CLK 1499
Query: 572 EELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDL 706
E+E+ K K++ + + E ++S +++ LE + E+E L
Sbjct: 1500 GEMEDDKSKMEKKESNLETELKSQTARIMELEDHITQKTIEIESL 1544
Score = 44.4 bits (100), Expect = 5e-04
Identities = 49/198 (24%), Positives = 102/198 (51%), Gaps = 7/198 (3%)
Frame = +2
Query: 152 AQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKL-------SIENSDLLRQLEEAES 310
A E+ + QLQ +L +++++ + + +++A KK + I+ DL++QLE+ S
Sbjct: 816 AYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNS 875
Query: 311 QVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKAD 490
++ Q K+K SLT E ++E + +L + N+ + +RE ++E E
Sbjct: 876 EMEQ--KVK-SLTQVYESKLEDGNKEQEQTKQILVEKENM---ILQMREGQKKEIE---I 926
Query: 491 LQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEK 670
L ++LS + +YE++ + +++E+ K+K A+E E+L +K++ E
Sbjct: 927 LTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQK-------AKEMQETLKKKLLDQE- 978
Query: 671 TKQRLATEVEDLQLEVDR 724
+L E+E+ LE+ +
Sbjct: 979 --AKLKKELENTALELSQ 994
Score = 36.7 bits (81), Expect = 0.094
Identities = 41/198 (20%), Positives = 84/198 (42%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD 214
E ++ +K K + ++ NDL L EK K + +LQ L ++ +
Sbjct: 1902 ENTEEKSKSHLVQPKLLSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEHQ 1961
Query: 215 EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEAR 394
+ +L+ KK+ E + ++Q E+ + ++ S +K + E +LA +E
Sbjct: 1962 Q------ELEILKKEYDQEREEKIKQ-EQEDLELKHNSTLKQLMR---EFNTQLAQKEQE 2011
Query: 395 ERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSE 574
T+ + + E +EE L +++++ + + + +YE AR E
Sbjct: 2012 LEMTIKETINKAQEVEAELLESHQEETN---QLLKKIAEKDDDLKRTAKRYEEILDAREE 2068
Query: 575 ELEEAKRKLQARLAEAEE 628
E+ R LQ +L E ++
Sbjct: 2069 EMTAKVRDLQTQLEELQK 2086
>X78998-1|CAA55632.1| 1411|Homo sapiens endosomal protein protein.
Length = 1411
Score = 51.6 bits (118), Expect = 3e-06
Identities = 45/234 (19%), Positives = 104/234 (44%), Gaps = 10/234 (4%)
Frame = +2
Query: 47 QLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANR 226
+L K K ++ Q E+N ++ L N EK +QLQ +NE++ +++ +
Sbjct: 914 ELKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQNEKEEQQLQGNINELKQSSEQKKK 973
Query: 227 TLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARE-RA 403
+ L K ++ ++L +L++ +Q +Q + + L++ + E ++ ++
Sbjct: 974 QIEALQGELKIAVLQKTELENKLQQQLTQAAQELAAEKEKISVLQNNYEKSQETFKQLQS 1033
Query: 404 TLLGKFRNL---EHDLDNIREQVEEEAEGKADLQRQLSKAN---AEAQLWRSKYESEGVA 565
G+ L DL ++ E++ E + Q+ N E + ++ E +
Sbjct: 1034 DFYGRESELLATRQDLKSVEEKLSLAQEDLISNRNQIGNQNKLIQELKTAKATLEQDSAK 1093
Query: 566 RSEELEE---AKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEV 718
+ ++L+E A + +Q + E+ + + K+ +E+ K R E+ L E+
Sbjct: 1094 KEQQLQERCKALQDIQKEKSLKEKELVNEKSKLAEIEEIKCRQEKEITKLNEEL 1147
Score = 51.6 bits (118), Expect = 3e-06
Identities = 54/249 (21%), Positives = 113/249 (45%), Gaps = 15/249 (6%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
++ M EQL Q + EK Q +N+L+ + + A + +K Q E+
Sbjct: 933 LNSMQEQLIQAQNTLKQNEKEEQQLQGNINELKQSSEQKKKQIEALQGELKIAVLQKTEL 992
Query: 200 QSK-ADEANRTLNDLDAAKKKLSI------ENSDLLRQLE-EAESQVSQLSKIKVSLTTQ 355
++K + + +L A K+K+S+ ++ + +QL+ + + S+L + L +
Sbjct: 993 ENKLQQQLTQAAQELAAEKEKISVLQNNYEKSQETFKQLQSDFYGRESELLATRQDLKS- 1051
Query: 356 LEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLW 535
+E+ LA E+ +G L +L + +E+++ K ++ KA + Q
Sbjct: 1052 VEEKLSLAQEDLISNRNQIGNQNKLIQELKTAKATLEQDSAKKEQQLQERCKALQDIQKE 1111
Query: 536 RSKYESEGV---ARSEELEEAKRKLQARLAEAEETIESLN----QKVVALEKTKQRLATE 694
+S E E V ++ E+EE K + + + + E ++S +++ L+ KQ L +
Sbjct: 1112 KSLKEKELVNEKSKLAEIEEIKCRQEKEITKLNEELKSHKLESIKEITNLKDAKQLLIQQ 1171
Query: 695 VEDLQLEVD 721
+LQ + D
Sbjct: 1172 KLELQGKAD 1180
Score = 51.2 bits (117), Expect = 4e-06
Identities = 54/246 (21%), Positives = 113/246 (45%), Gaps = 13/246 (5%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+ + + + +L KA E+ A+ ++ + L + EK+ +EK + + +L E+
Sbjct: 1070 IGNQNKLIQELKTAKATLEQDSAKKEQQLQERCKALQDIQKEKSLKEKELVNEKSKLAEI 1129
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKV-----SLTTQLED 364
+ + + L+ K +E+ + L++A+ + Q K+++ SL +E
Sbjct: 1130 EEIKCRQEKEITKLNEELKSHKLESIKEITNLKDAKQLLIQ-QKLELQGKADSLKAAVEQ 1188
Query: 365 TKR----LADEEARERATLLGKFRNLEHDLDN-IREQ---VEEEAEGKADLQRQLSKANA 520
KR L D+ +E L +F E L + I+E+ +++ E +A L Q++ N
Sbjct: 1189 EKRNQQILKDQVKKEEEELKKEFIEKEAKLHSEIKEKEVGMKKHEENEAKLTMQITALNE 1248
Query: 521 EAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVE 700
+ +++S R ELE+ L+ +A E T+++ + AL + + E+E
Sbjct: 1249 NLGTVKKEWQSSQ-RRVSELEKQTDDLRGEIAVLEATVQNNQDERRALLERCLKGEGEIE 1307
Query: 701 DLQLEV 718
LQ +V
Sbjct: 1308 KLQTKV 1313
Score = 49.2 bits (112), Expect = 2e-05
Identities = 61/240 (25%), Positives = 114/240 (47%), Gaps = 14/240 (5%)
Frame = +2
Query: 35 EQLDQLN-KLKAKAEKXR-AQ--YFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQ 202
EQ+ QL KLK ++E + AQ +V + +A L + + E V +L QLNE +
Sbjct: 575 EQVTQLTEKLKNQSESHKQAQENLHDQVQEQKAHLRAAQDRVLSLETSVNELNSQLNESK 634
Query: 203 SKADEANRTLND----LDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLED-T 367
K + + + L +A+ + + +DL L+ A++ + + +TTQL+ T
Sbjct: 635 EKVSQLDIQIKAKTELLLSAEAAKTAQRADLQNHLDTAQNALQDKQQELNKITTQLDQVT 694
Query: 368 KRLAD--EEARERATLLGKFRNLEHDLDNIREQVEEEAEG-KAD-LQRQLSKANAEAQLW 535
+L D E + + L +++ L+ E++E + + +AD L+ + SK A L
Sbjct: 695 AKLQDKQEHCSQLESHLKEYKEKYLSLEQKTEELEGQIKKLEADSLEVKASKEQALQDLQ 754
Query: 536 RSKYESEGVA-RSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQL 712
+ + + + R+ EL ++L+ T L +K ALE KQ+L + E+ Q+
Sbjct: 755 QQRQLNTDLELRATELS---KQLEMEKEIVSSTRLDLQKKSEALESIKQKLTKQEEEKQI 811
Score = 48.0 bits (109), Expect = 4e-05
Identities = 48/231 (20%), Positives = 102/231 (44%), Gaps = 9/231 (3%)
Frame = +2
Query: 29 MGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVK--QLQHQLNEVQ 202
+GE +L + + + + +V DL+ L L E+ +EK+ +LQHQL++ +
Sbjct: 430 LGEAHGRLKEQRQLSSEKLMDKEQQVADLQLKLSRL--EEQLKEKVTNSTELQHQLDKTK 487
Query: 203 SKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQL------SKIKVSLTTQLED 364
+ E A ++ + +LRQ+ + + ++ L SK +SL + +
Sbjct: 488 QQHQEQQALQQSTTAKLREAQNDLEQVLRQIGDKDQKIQNLEALLQKSKENISLLEKERE 547
Query: 365 TKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSK 544
+ +L + + H L Q+ E+ + +++ +Q ++ N Q+ K
Sbjct: 548 DLYAKIQAGEGETAVLNQLQEKNHTLQEQVTQLTEKLKNQSESHKQ-AQENLHDQVQEQK 606
Query: 545 YESEGVA-RSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATE 694
R LE + +L ++L E++E + L+ ++ A KT+ L+ E
Sbjct: 607 AHLRAAQDRVLSLETSVNELNSQLNESKEKVSQLDIQIKA--KTELLLSAE 655
Score = 30.3 bits (65), Expect = 8.2
Identities = 29/128 (22%), Positives = 56/128 (43%), Gaps = 3/128 (2%)
Frame = +2
Query: 344 LTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAE 523
L L++ K ++E +E L K++ L+ V + + L++QL +A E
Sbjct: 95 LQASLKEEKWYSEELKKE----LEKYQGLQQQEAKPDGLVTDSSAELQSLEQQLEEAQTE 150
Query: 524 ---AQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATE 694
+ + +E + + E+ + K K E E+ QKV L + + AT
Sbjct: 151 NFNIKQMKDLFEQKAAQLATEIADIKSKYD----EERSLREAAEQKVTRLTEELNKEATV 206
Query: 695 VEDLQLEV 718
++DL+ E+
Sbjct: 207 IQDLKTEL 214
>U41740-1|AAC50434.1| 2230|Homo sapiens trans-Golgi p230 protein.
Length = 2230
Score = 51.6 bits (118), Expect = 3e-06
Identities = 46/203 (22%), Positives = 92/203 (45%), Gaps = 15/203 (7%)
Frame = +2
Query: 143 EKAAQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQ 322
E K ++ LQ ++ ++ T+ L+ E L QL+E ++ +
Sbjct: 273 EDGTSVKTLETLQQRVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQLDERLQELEK 332
Query: 323 LSKI----KVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKAD 490
+ + K L TQL D K L ++ +++ ++ + + H E +E + E A
Sbjct: 333 IKDLHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMH------ETLEMKEEEIAQ 386
Query: 491 LQRQLSKANAEAQLWRSKYESEGVARSEELEEA----------KRKLQARLAEAEETIES 640
L+ ++ + + + R + E A EELE+A +RKL+A + E +TIE
Sbjct: 387 LRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEK 446
Query: 641 LNQKV-VALEKTKQRLATEVEDL 706
+++ ++L++ R+ EV D+
Sbjct: 447 TSEEERISLQQELSRVKQEVVDV 469
Score = 48.0 bits (109), Expect = 4e-05
Identities = 52/244 (21%), Positives = 108/244 (44%), Gaps = 17/244 (6%)
Frame = +2
Query: 44 DQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIV--KQLQHQLNEVQSKADE 217
+Q+ KL+ EK A+ + +L L E Q K+ K L Q K +
Sbjct: 476 EQIAKLQKLHEKELAR---KEQELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKEQQ 532
Query: 218 ANRTLNDLDAAKKKLSIENSDLLRQLE-EAESQVSQLSKIKVSLTTQLEDTKR------- 373
+ L +L+ KK + E+ + LR L+ EAE+ +++ +++ SL L++ K
Sbjct: 533 ESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAV 592
Query: 374 -LADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYE 550
L E+ + + + +L++++ Q + K + +Q + E + + E
Sbjct: 593 HLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQE 652
Query: 551 SEGVARSEEL------EEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQL 712
E + + +E+ EE K +L + +ESL+ ++ + K + +L E+ L+
Sbjct: 653 KETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKD 712
Query: 713 EVDR 724
+ D+
Sbjct: 713 QTDK 716
Score = 47.6 bits (108), Expect = 5e-05
Identities = 39/225 (17%), Positives = 100/225 (44%)
Frame = +2
Query: 32 GEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKA 211
G Q ++ ++ + + + +N + + L +K + KQL ++Q+
Sbjct: 1328 GNQQQAASEKESCITQLKKELSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSI 1387
Query: 212 DEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEA 391
+ + + + +K+ E +LL Q+++ +V LSK K+S Q++D E
Sbjct: 1388 SLSEKEAA-ISSLRKQYDEEKCELLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWK 1446
Query: 392 RERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARS 571
++ + +F ++ + ++ Q+E +++ + Q++ E +++
Sbjct: 1447 KKAQS---RFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFD----CLK 1499
Query: 572 EELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDL 706
E+E+ K K++ + + E ++S +++ LE + E+E L
Sbjct: 1500 GEMEDDKSKMEKKESNLETELKSQTARIMELEDHITQKTIEIESL 1544
Score = 44.4 bits (100), Expect = 5e-04
Identities = 49/198 (24%), Positives = 102/198 (51%), Gaps = 7/198 (3%)
Frame = +2
Query: 152 AQEKIVKQLQHQLNEVQSKADEANRTLNDLDAAKKKL-------SIENSDLLRQLEEAES 310
A E+ + QLQ +L +++++ + + +++A KK + I+ DL++QLE+ S
Sbjct: 816 AYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNS 875
Query: 311 QVSQLSKIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKAD 490
++ Q K+K SLT E ++E + +L + N+ + +RE ++E E
Sbjct: 876 EMEQ--KVK-SLTQVYESKLEDGNKEQEQTKQILVEKENM---ILQMREGQKKEIE---I 926
Query: 491 LQRQLSKANAEAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEK 670
L ++LS + +YE++ + +++E+ K+K A+E E+L +K++ E
Sbjct: 927 LTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQK-------AKEMQETLKKKLLDQE- 978
Query: 671 TKQRLATEVEDLQLEVDR 724
+L E+E+ LE+ +
Sbjct: 979 --AKLKKELENTALELSQ 994
Score = 36.7 bits (81), Expect = 0.094
Identities = 41/198 (20%), Positives = 84/198 (42%)
Frame = +2
Query: 35 EQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKAD 214
E ++ +K K + ++ NDL L EK K + +LQ L ++ +
Sbjct: 1902 ENTEEKSKSHLVQPKLLSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEHQ 1961
Query: 215 EANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEAR 394
+ +L+ KK+ E + ++Q E+ + ++ S +K + E +LA +E
Sbjct: 1962 Q------ELEILKKEYDQEREEKIKQ-EQEDLELKHNSTLKQLMR---EFNTQLAQKEQE 2011
Query: 395 ERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGVARSE 574
T+ + + E +EE L +++++ + + + +YE AR E
Sbjct: 2012 LEMTIKETINKAQEVEAELLESHQEETN---QLLKKIAEKDDDLKRTAKRYEEILDAREE 2068
Query: 575 ELEEAKRKLQARLAEAEE 628
E+ R LQ +L E ++
Sbjct: 2069 EMTAKVRDLQTQLEELQK 2086
>L40157-1|AAA79121.1| 1410|Homo sapiens endosome-associated protein
protein.
Length = 1410
Score = 51.6 bits (118), Expect = 3e-06
Identities = 45/234 (19%), Positives = 104/234 (44%), Gaps = 10/234 (4%)
Frame = +2
Query: 47 QLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEVQSKADEANR 226
+L K K ++ Q E+N ++ L N EK +QLQ +NE++ +++ +
Sbjct: 914 ELKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQNEKEEQQLQGNINELKQSSEQKKK 973
Query: 227 TLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLADEEARE-RA 403
+ L K ++ ++L +L++ +Q +Q + + L++ + E ++ ++
Sbjct: 974 QIEALQGELKIAVLQKTELENKLQQQLTQAAQELAAEKEKISVLQNNYEKSQETFKQLQS 1033
Query: 404 TLLGKFRNL---EHDLDNIREQVEEEAEGKADLQRQLSKAN---AEAQLWRSKYESEGVA 565
G+ L DL ++ E++ E + Q+ N E + ++ E +
Sbjct: 1034 DFYGRESELLATRQDLKSVEEKLSLAQEDLISNRNQIGNQNKLIQELKTAKATLEQDSAK 1093
Query: 566 RSEELEE---AKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEV 718
+ ++L+E A + +Q + E+ + + K+ +E+ K R E+ L E+
Sbjct: 1094 KEQQLQERCKALQDIQKEKSLKEKELVNEKSKLAEIEEIKCRQEKEITKLNEEL 1147
Score = 51.6 bits (118), Expect = 3e-06
Identities = 54/249 (21%), Positives = 113/249 (45%), Gaps = 15/249 (6%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
++ M EQL Q + EK Q +N+L+ + + A + +K Q E+
Sbjct: 933 LNSMQEQLIQAQNTLKQNEKEEQQLQGNINELKQSSEQKKKQIEALQGELKIAVLQKTEL 992
Query: 200 QSK-ADEANRTLNDLDAAKKKLSI------ENSDLLRQLE-EAESQVSQLSKIKVSLTTQ 355
++K + + +L A K+K+S+ ++ + +QL+ + + S+L + L +
Sbjct: 993 ENKLQQQLTQAAQELAAEKEKISVLQNNYEKSQETFKQLQSDFYGRESELLATRQDLKS- 1051
Query: 356 LEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLW 535
+E+ LA E+ +G L +L + +E+++ K ++ KA + Q
Sbjct: 1052 VEEKLSLAQEDLISNRNQIGNQNKLIQELKTAKATLEQDSAKKEQQLQERCKALQDIQKE 1111
Query: 536 RSKYESEGV---ARSEELEEAKRKLQARLAEAEETIESLN----QKVVALEKTKQRLATE 694
+S E E V ++ E+EE K + + + + E ++S +++ L+ KQ L +
Sbjct: 1112 KSLKEKELVNEKSKLAEIEEIKCRQEKEITKLNEELKSHKLESIKEITNLKDAKQLLIQQ 1171
Query: 695 VEDLQLEVD 721
+LQ + D
Sbjct: 1172 KLELQGKAD 1180
Score = 51.2 bits (117), Expect = 4e-06
Identities = 54/246 (21%), Positives = 113/246 (45%), Gaps = 13/246 (5%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNEV 199
+ + + + +L KA E+ A+ ++ + L + EK+ +EK + + +L E+
Sbjct: 1070 IGNQNKLIQELKTAKATLEQDSAKKEQQLQERCKALQDIQKEKSLKEKELVNEKSKLAEI 1129
Query: 200 QSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKV-----SLTTQLED 364
+ + + L+ K +E+ + L++A+ + Q K+++ SL +E
Sbjct: 1130 EEIKCRQEKEITKLNEELKSHKLESIKEITNLKDAKQLLIQ-QKLELQGKADSLKAAVEQ 1188
Query: 365 TKR----LADEEARERATLLGKFRNLEHDLDN-IREQ---VEEEAEGKADLQRQLSKANA 520
KR L D+ +E L +F E L + I+E+ +++ E +A L Q++ N
Sbjct: 1189 EKRNQQILKDQVKKEEEELKKEFIEKEAKLHSEIKEKEVGMKKHEENEAKLTMQITALNE 1248
Query: 521 EAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVE 700
+ +++S R ELE+ L+ +A E T+++ + AL + + E+E
Sbjct: 1249 NLGTVKKEWQSSQ-RRVSELEKQTDDLRGEIAVLEATVQNNQDERRALLERCLKGEGEIE 1307
Query: 701 DLQLEV 718
LQ +V
Sbjct: 1308 KLQTKV 1313
Score = 49.6 bits (113), Expect = 1e-05
Identities = 49/231 (21%), Positives = 102/231 (44%), Gaps = 9/231 (3%)
Frame = +2
Query: 29 MGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKIVK--QLQHQLNEVQ 202
+GE +L + + + + +V DL+ L L E+ +EK+ +LQHQL++ +
Sbjct: 430 LGEAHGRLKEQRQLSSEKLMDKEQQVADLQLKLSRL--EEQLKEKVTNSTELQHQLDKTK 487
Query: 203 SKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQL------SKIKVSLTTQLED 364
+ E A ++ + +LRQ+ E + ++ L SK +SL + +
Sbjct: 488 QQHQEQQALQQSTTAKLREAQNDLEQVLRQIGEKDQKIQNLEALLQKSKENISLLEKERE 547
Query: 365 TKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSK 544
+ +L + + H L + Q+ E + +++ +Q ++ N Q+ K
Sbjct: 548 DLYAKIQAGEGETAVLNQLQEKNHTLQDEVTQLTENVKNQSESHKQ-AQENLHDQVQEQK 606
Query: 545 YESEGVA-RSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATE 694
R LE + +L ++L E++E + L+ ++ A KT+ L+ E
Sbjct: 607 AHLRAAQDRVLSLETSVNELNSQLNESKEKVSQLDIQIKA--KTELLLSAE 655
Score = 45.6 bits (103), Expect = 2e-04
Identities = 56/242 (23%), Positives = 112/242 (46%), Gaps = 11/242 (4%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEK-XRAQYFSEVNDLRAGLDHLSNEKAAQEKIVKQLQHQLNE 196
+ D QL + K ++++ K + +V + +A L + + E V +L QLNE
Sbjct: 573 LQDEVTQLTENVKNQSESHKQAQENLHDQVQEQKAHLRAAQDRVLSLETSVNELNSQLNE 632
Query: 197 VQSKADEANRTLND----LDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLED 364
+ K + + + L +A+ + + +DL L+ A++ + + +TTQL+
Sbjct: 633 SKEKVSQLDIQIKAKTELLLSAEAAKTAQRADLQNHLDTAQNALQDKHQELNKITTQLDQ 692
Query: 365 -TKRLAD--EEARERATLLGKFRNLEHDLDNIREQVEEEAEG-KAD-LQRQLSKANAEAQ 529
T +L D E + + L +++ L+ E++E + + +AD L+ + SK A
Sbjct: 693 VTAKLQDKQEHCSQLESHLKEYKEKYLSLEQKTEELEGQIKKLEADSLEVKASKEQALQD 752
Query: 530 LWRSKYESEGVA-RSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDL 706
L + + + + R+ EL ++L+ T L +K ALE KQ+L + E+
Sbjct: 753 LQQQRQLNTDLELRATELS---KQLEMEKEIVSSTRLDLQKKSEALESIKQKLTKQEEEK 809
Query: 707 QL 712
Q+
Sbjct: 810 QI 811
Score = 40.7 bits (91), Expect = 0.006
Identities = 55/258 (21%), Positives = 104/258 (40%), Gaps = 23/258 (8%)
Frame = +2
Query: 20 VSDMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNEKAAQEKI--VKQLQHQLN 193
++D+ + D+ L+ AE+ + E+N + L E + I V L+ +L
Sbjct: 172 IADIKSKYDEERSLREAAEQKVTRLTEELNKEATVIQDLKTELLQRPGIEDVAVLKKELV 231
Query: 194 EVQSKAD----EANRTLNDLDAAKKKLSIE-----------NSDLLRQLEEAESQVSQLS 328
+VQ+ D E R L KK + S+L + +E V +L
Sbjct: 232 QVQTLMDNMTLERERESEKLKDESKKFESQYASSEATISQLRSELSKGPQEVRVYVQELQ 291
Query: 329 KIKVSLTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLS 508
K+K S+ +E ++ TL E D + E+ EE+ K ++Q L
Sbjct: 292 KLKSSV-----------NELTQKNQTLTENLLKKEQDYTKLEEKHNEESVSKKNIQATLH 340
Query: 509 KANAEAQLWRSKYESEGVA------RSEELEEAKRKLQARLAEAEETIESLNQKVVALEK 670
+ + + Q +S+ + + E EA +KL+ L+E E + L + L++
Sbjct: 341 QKDLDCQQLQSRLSASETSLHRIHVELSEKGEATQKLKEELSEVETKYQHLKAEFKQLQQ 400
Query: 671 TKQRLATEVEDLQLEVDR 724
++ LQ E+++
Sbjct: 401 QREEKEQHGLQLQSEINQ 418
Score = 30.3 bits (65), Expect = 8.2
Identities = 29/128 (22%), Positives = 56/128 (43%), Gaps = 3/128 (2%)
Frame = +2
Query: 344 LTTQLEDTKRLADEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAE 523
L L++ K ++E +E L K++ L+ V + + L++QL +A E
Sbjct: 95 LQASLKEEKWYSEELKKE----LEKYQGLQQQEAKPDGLVTDSSAELQSLEQQLEEAQTE 150
Query: 524 ---AQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATE 694
+ + +E + + E+ + K K E E+ QKV L + + AT
Sbjct: 151 NFNIKQMKDLFEQKAAQLATEIADIKSKYD----EERSLREAAEQKVTRLTEELNKEATV 206
Query: 695 VEDLQLEV 718
++DL+ E+
Sbjct: 207 IQDLKTEL 214
>BC000616-1|AAH00616.1| 585|Homo sapiens SWAP-70 protein protein.
Length = 585
Score = 51.6 bits (118), Expect = 3e-06
Identities = 45/164 (27%), Positives = 82/164 (50%), Gaps = 6/164 (3%)
Frame = +2
Query: 251 KKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLED-TKRLADEEARERATLLGKFRN 427
+KK E +L RQ++E ++ + ++ +LE+ R A+EE + T +
Sbjct: 327 RKKQLAEQEELERQMKELQAANESKQQELEAVRKKLEEAASRAAEEEKKRLQTQVELQAR 386
Query: 428 LEHDLDN---IREQVEEE-AEGKADLQRQLSKANAEAQLWRSKYES-EGVARSEELEEAK 592
+L+ IR+Q+EE+ A+ ++L++ L + ++ E+ E ++ + EE
Sbjct: 387 FSTELEREKLIRQQMEEQVAQKSSELEQYLQRVRELEDMYLKLQEALEDERQARQDEETV 446
Query: 593 RKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
RKLQARL E EE+ + + LE+ + TE E +LE R
Sbjct: 447 RKLQARLLE-EESSKRAELEKWHLEQQQAIQTTEAEKQELENQR 489
Score = 46.0 bits (104), Expect = 2e-04
Identities = 40/185 (21%), Positives = 93/185 (50%), Gaps = 3/185 (1%)
Frame = +2
Query: 170 KQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLT 349
++L+ Q+ E+Q+ A+E+ + +L+A +KKL S R EE + ++ +++ +
Sbjct: 335 EELERQMKELQA-ANESKQ--QELEAVRKKLEEAAS---RAAEEEKKRLQTQVELQARFS 388
Query: 350 TQLEDTKRLA---DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANA 520
T+LE K + +E+ ++++ L ++ +L+++ +++E E +RQ +
Sbjct: 389 TELEREKLIRQQMEEQVAQKSSELEQYLQRVRELEDMYLKLQEALED----ERQARQDEE 444
Query: 521 EAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVE 700
+ +++ E ++ ELE+ + Q + E + L + V E+ Q ++E
Sbjct: 445 TVRKLQARLLEEESSKRAELEKWHLEQQQAIQTTEAEKQELENQRVLKEQALQEAMEQLE 504
Query: 701 DLQLE 715
L+LE
Sbjct: 505 QLELE 509
Score = 35.1 bits (77), Expect = 0.29
Identities = 21/65 (32%), Positives = 37/65 (56%), Gaps = 5/65 (7%)
Frame = +2
Query: 521 EAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVV-----ALEKTKQRL 685
EA+ R + + +A EELE ++LQA ++ +E++ +K+ A E+ K+RL
Sbjct: 318 EARQRRKELRKKQLAEQEELERQMKELQAANESKQQELEAVRKKLEEAASRAAEEEKKRL 377
Query: 686 ATEVE 700
T+VE
Sbjct: 378 QTQVE 382
>AL590431-10|CAH71268.1| 247|Homo sapiens tropomyosin 3 protein.
Length = 247
Score = 51.6 bits (118), Expect = 3e-06
Identities = 59/230 (25%), Positives = 104/230 (45%), Gaps = 5/230 (2%)
Frame = +2
Query: 26 DMGEQLDQLNKLKAKAEKXRAQYFSEVNDLRAGLDHLSNE-KAAQEKIVKQLQHQLNEVQ 202
D E+ ++L + + R Q +EV L + + E AQE++ LQ +L E +
Sbjct: 23 DAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLATALQ-KLEEAE 81
Query: 203 SKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLEDTKRLAD 382
ADE+ R + IEN R L++ E +L +I QL++ K +A+
Sbjct: 82 KAADESERGMK---------VIEN----RALKDEEKM--ELQEI------QLKEAKHIAE 120
Query: 383 EEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANAEAQLWRSKYESEGV 562
E R+ + K +E DL+ E+ E ++L+ +L + ++ E
Sbjct: 121 EADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYS- 179
Query: 563 ARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKT----KQRLATEVE 700
+ ++ EE + L +L EAE E + V LEKT ++RL +++E
Sbjct: 180 QKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLE 229
>AF210818-1|AAF24486.1| 585|Homo sapiens SWAP-70 protein.
Length = 585
Score = 51.6 bits (118), Expect = 3e-06
Identities = 45/164 (27%), Positives = 82/164 (50%), Gaps = 6/164 (3%)
Frame = +2
Query: 251 KKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLED-TKRLADEEARERATLLGKFRN 427
+KK E +L RQ++E ++ + ++ +LE+ R A+EE + T +
Sbjct: 327 RKKQLAEQEELERQMKELQAANESKQQELEAVRKKLEEAASRAAEEEKKRLQTQVELQAR 386
Query: 428 LEHDLDN---IREQVEEE-AEGKADLQRQLSKANAEAQLWRSKYES-EGVARSEELEEAK 592
+L+ IR+Q+EE+ A+ ++L++ L + ++ E+ E ++ + EE
Sbjct: 387 FSTELEREKLIRQQMEEQVAQKSSELEQYLQRVRELEDMYLKLQEALEDERQARQDEETV 446
Query: 593 RKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
RKLQARL E EE+ + + LE+ + TE E +LE R
Sbjct: 447 RKLQARLLE-EESSKRAELEKWHLEQQQAIQTTEAEKQELENQR 489
Score = 46.0 bits (104), Expect = 2e-04
Identities = 40/185 (21%), Positives = 93/185 (50%), Gaps = 3/185 (1%)
Frame = +2
Query: 170 KQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLT 349
++L+ Q+ E+Q+ A+E+ + +L+A +KKL S R EE + ++ +++ +
Sbjct: 335 EELERQMKELQA-ANESKQ--QELEAVRKKLEEAAS---RAAEEEKKRLQTQVELQARFS 388
Query: 350 TQLEDTKRLA---DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANA 520
T+LE K + +E+ ++++ L ++ +L+++ +++E E +RQ +
Sbjct: 389 TELEREKLIRQQMEEQVAQKSSELEQYLQRVRELEDMYLKLQEALED----ERQARQDEE 444
Query: 521 EAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVE 700
+ +++ E ++ ELE+ + Q + E + L + V E+ Q ++E
Sbjct: 445 TVRKLQARLLEEESSKRAELEKWHLEQQQAIQTTEAEKQELENQRVLKEQALQEAMEQLE 504
Query: 701 DLQLE 715
L+LE
Sbjct: 505 QLELE 509
Score = 35.1 bits (77), Expect = 0.29
Identities = 21/65 (32%), Positives = 37/65 (56%), Gaps = 5/65 (7%)
Frame = +2
Query: 521 EAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVV-----ALEKTKQRL 685
EA+ R + + +A EELE ++LQA ++ +E++ +K+ A E+ K+RL
Sbjct: 318 EARQRRKELRKKQLAEQEELERQMKELQAANESKQQELEAVRKKLEEAASRAAEEEKKRL 377
Query: 686 ATEVE 700
T+VE
Sbjct: 378 QTQVE 382
>AF134894-1|AAF61403.1| 585|Homo sapiens SWAP-70 homolog protein.
Length = 585
Score = 51.6 bits (118), Expect = 3e-06
Identities = 45/164 (27%), Positives = 82/164 (50%), Gaps = 6/164 (3%)
Frame = +2
Query: 251 KKKLSIENSDLLRQLEEAESQVSQLSKIKVSLTTQLED-TKRLADEEARERATLLGKFRN 427
+KK E +L RQ++E ++ + ++ +LE+ R A+EE + T +
Sbjct: 327 RKKQLAEQEELERQMKELQAANESKQQELEAVRKKLEEAASRAAEEEKKRLQTQVELQAR 386
Query: 428 LEHDLDN---IREQVEEE-AEGKADLQRQLSKANAEAQLWRSKYES-EGVARSEELEEAK 592
+L+ IR+Q+EE+ A+ ++L++ L + ++ E+ E ++ + EE
Sbjct: 387 FSTELEREKLIRQQMEEQVAQKSSELEQYLQRVRELEDMYLKLQEALEDERQARQDEETV 446
Query: 593 RKLQARLAEAEETIESLNQKVVALEKTKQRLATEVEDLQLEVDR 724
RKLQARL E EE+ + + LE+ + TE E +LE R
Sbjct: 447 RKLQARLLE-EESSKRAELEKWHLEQQQAIQTTEAEKQELENQR 489
Score = 46.8 bits (106), Expect = 9e-05
Identities = 40/185 (21%), Positives = 94/185 (50%), Gaps = 3/185 (1%)
Frame = +2
Query: 170 KQLQHQLNEVQSKADEANRTLNDLDAAKKKLSIENSDLLRQLEEAESQVSQLSKIKVSLT 349
++L+ Q+ E+Q+ A+E+ + +L+A +KKL S R EE + ++ +++ +
Sbjct: 335 EELERQMKELQA-ANESKQ--QELEAVRKKLEEAAS---RAAEEEKKRLQTQVELQARFS 388
Query: 350 TQLEDTKRLA---DEEARERATLLGKFRNLEHDLDNIREQVEEEAEGKADLQRQLSKANA 520
T+LE K + +E+ ++++ L ++ +L+++ +++E E +RQ +
Sbjct: 389 TELEREKLIRQQMEEQVAQKSSELEQYLQRVRELEDMYLKLQEALED----ERQARQDEE 444
Query: 521 EAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVVALEKTKQRLATEVE 700
+ +++ E ++ ELE+ + Q + E + L + V E+ Q ++E
Sbjct: 445 TVRKLQARLLEEESSKRAELEKWHLEQQQAIQTTEAEKQELENQRVLKEQALQEAMEQLE 504
Query: 701 DLQLE 715
+L+LE
Sbjct: 505 ELELE 509
Score = 35.1 bits (77), Expect = 0.29
Identities = 21/65 (32%), Positives = 37/65 (56%), Gaps = 5/65 (7%)
Frame = +2
Query: 521 EAQLWRSKYESEGVARSEELEEAKRKLQARLAEAEETIESLNQKVV-----ALEKTKQRL 685
EA+ R + + +A EELE ++LQA ++ +E++ +K+ A E+ K+RL
Sbjct: 318 EARQRRKELRKKQLAEQEELERQMKELQAANESKQQELEAVRKKLEEAASRAAEEEKKRL 377
Query: 686 ATEVE 700
T+VE
Sbjct: 378 QTQVE 382
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 86,688,827
Number of Sequences: 237096
Number of extensions: 1818324
Number of successful extensions: 18013
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 11791
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 16430
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 9534535578
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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