Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P10_F_C04
(765 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
Z14093-1|CAA78475.1| 445|Homo sapiens branched chain decarboxyl... 285 1e-76
S62652-1|AAB20222.2| 443|Homo sapiens branched-chain alpha-keto... 285 1e-76
S38327-1|AAB19268.2| 387|Homo sapiens protein ( branched-chain ... 285 1e-76
J04474-1|AAB59549.1| 444|Homo sapiens branched-chain alpha-keto... 285 1e-76
BC023983-1|AAH23983.1| 445|Homo sapiens branched chain keto aci... 285 1e-76
BC008933-1|AAH08933.1| 445|Homo sapiens branched chain keto aci... 285 1e-76
BC007878-1|AAH07878.1| 445|Homo sapiens branched chain keto aci... 285 1e-76
AB209828-1|BAD93065.1| 444|Homo sapiens branched chain keto aci... 285 1e-76
AK127598-1|BAC87051.1| 479|Homo sapiens 1.2.4.4). protein. 284 3e-76
M22221-1|AAA35590.1| 378|Homo sapiens protein ( Human branched-... 268 2e-71
M86808-1|AAA60232.1| 388|Homo sapiens pyruvate dehydrogenase co... 68 4e-11
BC127638-1|AAI27639.1| 388|Homo sapiens pyruvate dehydrogenase ... 68 4e-11
BC127637-1|AAI27638.1| 388|Homo sapiens pyruvate dehydrogenase ... 68 4e-11
BC119657-1|AAI19658.1| 388|Homo sapiens pyruvate dehydrogenase ... 68 4e-11
BC119656-1|AAI19657.1| 388|Homo sapiens pyruvate dehydrogenase ... 68 4e-11
BC094760-1|AAH94760.1| 407|Homo sapiens PDHA2 protein protein. 68 4e-11
BC030697-1|AAH30697.3| 388|Homo sapiens pyruvate dehydrogenase ... 68 4e-11
BC066953-1|AAH66953.2| 388|Homo sapiens pyruvate dehydrogenase ... 66 1e-10
X52710-1|CAA36934.1| 390|Homo sapiens protein ( Human mRNA for ... 62 2e-09
X52709-1|CAA36933.1| 390|Homo sapiens protein ( Human mRNA for ... 62 2e-09
M27257-1|AAA60051.1| 390|Homo sapiens pyruvate dehydrogenase E1... 62 2e-09
M24848-1|AAA36533.1| 390|Homo sapiens protein ( Human pyruvate ... 62 2e-09
L13318-1|AAA60227.1| 390|Homo sapiens pyruvate dehydrogenase E1... 62 2e-09
J03575-1|AAA60050.1| 390|Homo sapiens pyruvate dehydrogenase al... 62 2e-09
J03503-1|AAA60055.1| 414|Homo sapiens PDHA1 protein. 62 2e-09
EF590117-1|ABQ59099.1| 428|Homo sapiens mitochondrial PDHA1 pro... 62 2e-09
D90084-1|BAA14121.1| 390|Homo sapiens pyruvate dehydrogenase al... 62 2e-09
BC002406-1|AAH02406.1| 390|Homo sapiens pyruvate dehydrogenase ... 62 2e-09
AL732326-7|CAI41291.1| 390|Homo sapiens pyruvate dehydrogenase ... 62 2e-09
AK222988-1|BAD96708.1| 390|Homo sapiens pyruvate dehydrogenase ... 62 2e-09
AK222740-1|BAD96460.1| 390|Homo sapiens pyruvate dehydrogenase ... 62 2e-09
AL732326-6|CAI41290.1| 204|Homo sapiens pyruvate dehydrogenase ... 45 3e-04
EF576990-1|ABQ58815.1| 261|Homo sapiens PDHA1 protein. 42 0.003
AM746210-1|CAN88919.1| 302|Homo sapiens PDHA1/LOC79064 protein ... 40 0.013
CR533560-1|CAG38591.1| 626|Homo sapiens DKFZP434L1717 protein. 36 0.16
BC142943-1|AAI42944.1| 626|Homo sapiens transketolase-like 2 pr... 36 0.16
BC125101-1|AAI25102.1| 626|Homo sapiens transketolase-like 2 pr... 36 0.16
BC028707-1|AAH28707.4| 626|Homo sapiens transketolase-like 2 pr... 36 0.16
AK057325-1|BAB71427.1| 626|Homo sapiens protein ( Homo sapiens ... 36 0.16
L48690-1|AAB59581.1| 390|Homo sapiens pyruvate dehydrogenase E1... 35 0.37
AL732326-5|CAI41289.1| 180|Homo sapiens pyruvate dehydrogenase ... 35 0.37
AL732326-4|CAI41288.1| 205|Homo sapiens pyruvate dehydrogenase ... 35 0.37
X67688-1|CAA47919.1| 623|Homo sapiens transketolase protein. 31 3.4
U55017-1|AAA98961.1| 623|Homo sapiens transketolase protein. 31 3.4
L12711-1|AAA61222.1| 623|Homo sapiens transketolase protein. 31 3.4
BC024026-1|AAH24026.2| 536|Homo sapiens TKT protein protein. 31 3.4
BC009970-1|AAH09970.1| 623|Homo sapiens transketolase (Wernicke... 31 3.4
AK223614-1|BAD97334.1| 623|Homo sapiens transketolase variant p... 31 3.4
L23808-1|AAA58658.1| 470|Homo sapiens metalloproteinase protein. 30 7.9
BC112301-1|AAI12302.1| 470|Homo sapiens matrix metalloproteinas... 30 7.9
AY856072-1|AAW29944.1| 470|Homo sapiens matrix metalloproteinas... 30 7.9
>Z14093-1|CAA78475.1| 445|Homo sapiens branched chain decarboxylase
alpha subunit protein.
Length = 445
Score = 285 bits (699), Expect = 1e-76
Identities = 133/208 (63%), Positives = 158/208 (75%)
Frame = +2
Query: 140 EFPGARAPYVSEMKFFNETSYEPIPIYRVMDNNGQIIDKNEEPNLDKATLINMYKTMVQL 319
+FPGA A ++ +++F IPIYRVMD GQII+ +E+P+L K ++ +YK+M L
Sbjct: 53 QFPGASAEFIDKLEFIQPNVISGIPIYRVMDRQGQIINPSEDPHLPKEKVLKLYKSMTLL 112
Query: 320 SHMDKILYESQRQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVT 499
+ MD+ILYESQRQGRISFYMTNYGEEG H+GSA+AL DLVF QYRE GV +YR +
Sbjct: 113 NTMDRILYESQRQGRISFYMTNYGEEGTHVGSAAALDNTDLVFGQYREAGVLMYRDYPLE 172
Query: 500 ELVNQCYGNCEDPGKGRQMPVHYGSKHHNMVTISSPLGTQMPQAVGAAYAYKRVPNNDRC 679
+ QCYGN D GKGRQMPVHYG K + VTISSPL TQ+PQAVGAAYA KR N +R
Sbjct: 173 LFMAQCYGNISDLGKGRQMPVHYGCKERHFVTISSPLATQIPQAVGAAYAAKRA-NANRV 231
Query: 680 VICYFGDGAASEGDAHAAFNFAATLXCP 763
VICYFG+GAASEGDAHA FNFAATL CP
Sbjct: 232 VICYFGEGAASEGDAHAGFNFAATLECP 259
>S62652-1|AAB20222.2| 443|Homo sapiens branched-chain alpha-keto
acid dehydrogenase E1 alpha subunit protein.
Length = 443
Score = 285 bits (699), Expect = 1e-76
Identities = 133/208 (63%), Positives = 158/208 (75%)
Frame = +2
Query: 140 EFPGARAPYVSEMKFFNETSYEPIPIYRVMDNNGQIIDKNEEPNLDKATLINMYKTMVQL 319
+FPGA A ++ +++F IPIYRVMD GQII+ +E+P+L K ++ +YK+M L
Sbjct: 51 QFPGASAEFIDKLEFIQPNVISGIPIYRVMDRQGQIINPSEDPHLPKEKVLKLYKSMTLL 110
Query: 320 SHMDKILYESQRQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVT 499
+ MD+ILYESQRQGRISFYMTNYGEEG H+GSA+AL DLVF QYRE GV +YR +
Sbjct: 111 NTMDRILYESQRQGRISFYMTNYGEEGTHVGSAAALDNTDLVFGQYREAGVLMYRDYPLE 170
Query: 500 ELVNQCYGNCEDPGKGRQMPVHYGSKHHNMVTISSPLGTQMPQAVGAAYAYKRVPNNDRC 679
+ QCYGN D GKGRQMPVHYG K + VTISSPL TQ+PQAVGAAYA KR N +R
Sbjct: 171 LFMAQCYGNISDLGKGRQMPVHYGCKERHFVTISSPLATQIPQAVGAAYAAKRA-NANRV 229
Query: 680 VICYFGDGAASEGDAHAAFNFAATLXCP 763
VICYFG+GAASEGDAHA FNFAATL CP
Sbjct: 230 VICYFGEGAASEGDAHAGFNFAATLECP 257
>S38327-1|AAB19268.2| 387|Homo sapiens protein ( branched-chain
alpha-keto acid dehydrogenase complex E1 alpha subunit
[human, Genomic, 195 nt, segment 8 of 8]. ).
Length = 387
Score = 285 bits (699), Expect = 1e-76
Identities = 133/208 (63%), Positives = 158/208 (75%)
Frame = +2
Query: 140 EFPGARAPYVSEMKFFNETSYEPIPIYRVMDNNGQIIDKNEEPNLDKATLINMYKTMVQL 319
+FPGA A ++ +++F IPIYRVMD GQII+ +E+P+L K ++ +YK+M L
Sbjct: 51 QFPGASAEFIDKLEFIQPNVISGIPIYRVMDRQGQIINPSEDPHLPKEKVLKLYKSMTLL 110
Query: 320 SHMDKILYESQRQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVT 499
+ MD+ILYESQRQGRISFYMTNYGEEG H+GSA+AL DLVF QYRE GV +YR +
Sbjct: 111 NTMDRILYESQRQGRISFYMTNYGEEGTHVGSAAALDNTDLVFGQYREAGVLMYRDYPLE 170
Query: 500 ELVNQCYGNCEDPGKGRQMPVHYGSKHHNMVTISSPLGTQMPQAVGAAYAYKRVPNNDRC 679
+ QCYGN D GKGRQMPVHYG K + VTISSPL TQ+PQAVGAAYA KR N +R
Sbjct: 171 LFMAQCYGNISDLGKGRQMPVHYGCKERHFVTISSPLATQIPQAVGAAYAAKRA-NANRV 229
Query: 680 VICYFGDGAASEGDAHAAFNFAATLXCP 763
VICYFG+GAASEGDAHA FNFAATL CP
Sbjct: 230 VICYFGEGAASEGDAHAGFNFAATLECP 257
>J04474-1|AAB59549.1| 444|Homo sapiens branched-chain alpha-keto
acid dehydrogenase protein.
Length = 444
Score = 285 bits (699), Expect = 1e-76
Identities = 133/208 (63%), Positives = 158/208 (75%)
Frame = +2
Query: 140 EFPGARAPYVSEMKFFNETSYEPIPIYRVMDNNGQIIDKNEEPNLDKATLINMYKTMVQL 319
+FPGA A ++ +++F IPIYRVMD GQII+ +E+P+L K ++ +YK+M L
Sbjct: 52 QFPGASAEFIDKLEFIQPNVISGIPIYRVMDRQGQIINPSEDPHLPKEKVLKLYKSMTLL 111
Query: 320 SHMDKILYESQRQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVT 499
+ MD+ILYESQRQGRISFYMTNYGEEG H+GSA+AL DLVF QYRE GV +YR +
Sbjct: 112 NTMDRILYESQRQGRISFYMTNYGEEGTHVGSAAALDNTDLVFGQYREAGVLMYRDYPLE 171
Query: 500 ELVNQCYGNCEDPGKGRQMPVHYGSKHHNMVTISSPLGTQMPQAVGAAYAYKRVPNNDRC 679
+ QCYGN D GKGRQMPVHYG K + VTISSPL TQ+PQAVGAAYA KR N +R
Sbjct: 172 LFMAQCYGNISDLGKGRQMPVHYGCKERHFVTISSPLATQIPQAVGAAYAAKRA-NANRV 230
Query: 680 VICYFGDGAASEGDAHAAFNFAATLXCP 763
VICYFG+GAASEGDAHA FNFAATL CP
Sbjct: 231 VICYFGEGAASEGDAHAGFNFAATLECP 258
>BC023983-1|AAH23983.1| 445|Homo sapiens branched chain keto acid
dehydrogenase E1, alpha polypeptide protein.
Length = 445
Score = 285 bits (699), Expect = 1e-76
Identities = 133/208 (63%), Positives = 158/208 (75%)
Frame = +2
Query: 140 EFPGARAPYVSEMKFFNETSYEPIPIYRVMDNNGQIIDKNEEPNLDKATLINMYKTMVQL 319
+FPGA A ++ +++F IPIYRVMD GQII+ +E+P+L K ++ +YK+M L
Sbjct: 53 QFPGASAEFIDKLEFIQPNVISGIPIYRVMDRQGQIINPSEDPHLPKEKVLKLYKSMTLL 112
Query: 320 SHMDKILYESQRQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVT 499
+ MD+ILYESQRQGRISFYMTNYGEEG H+GSA+AL DLVF QYRE GV +YR +
Sbjct: 113 NTMDRILYESQRQGRISFYMTNYGEEGTHVGSAAALDNTDLVFGQYREAGVLMYRDYPLE 172
Query: 500 ELVNQCYGNCEDPGKGRQMPVHYGSKHHNMVTISSPLGTQMPQAVGAAYAYKRVPNNDRC 679
+ QCYGN D GKGRQMPVHYG K + VTISSPL TQ+PQAVGAAYA KR N +R
Sbjct: 173 LFMAQCYGNISDLGKGRQMPVHYGCKERHFVTISSPLATQIPQAVGAAYAAKRA-NANRV 231
Query: 680 VICYFGDGAASEGDAHAAFNFAATLXCP 763
VICYFG+GAASEGDAHA FNFAATL CP
Sbjct: 232 VICYFGEGAASEGDAHAGFNFAATLECP 259
>BC008933-1|AAH08933.1| 445|Homo sapiens branched chain keto acid
dehydrogenase E1, alpha polypeptide protein.
Length = 445
Score = 285 bits (699), Expect = 1e-76
Identities = 133/208 (63%), Positives = 158/208 (75%)
Frame = +2
Query: 140 EFPGARAPYVSEMKFFNETSYEPIPIYRVMDNNGQIIDKNEEPNLDKATLINMYKTMVQL 319
+FPGA A ++ +++F IPIYRVMD GQII+ +E+P+L K ++ +YK+M L
Sbjct: 53 QFPGASAEFIDKLEFIQPNVISGIPIYRVMDRQGQIINPSEDPHLPKEKVLKLYKSMTLL 112
Query: 320 SHMDKILYESQRQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVT 499
+ MD+ILYESQRQGRISFYMTNYGEEG H+GSA+AL DLVF QYRE GV +YR +
Sbjct: 113 NTMDRILYESQRQGRISFYMTNYGEEGTHVGSAAALDNTDLVFGQYREAGVLMYRDYPLE 172
Query: 500 ELVNQCYGNCEDPGKGRQMPVHYGSKHHNMVTISSPLGTQMPQAVGAAYAYKRVPNNDRC 679
+ QCYGN D GKGRQMPVHYG K + VTISSPL TQ+PQAVGAAYA KR N +R
Sbjct: 173 LFMAQCYGNISDLGKGRQMPVHYGCKERHFVTISSPLATQIPQAVGAAYAAKRA-NANRV 231
Query: 680 VICYFGDGAASEGDAHAAFNFAATLXCP 763
VICYFG+GAASEGDAHA FNFAATL CP
Sbjct: 232 VICYFGEGAASEGDAHAGFNFAATLECP 259
>BC007878-1|AAH07878.1| 445|Homo sapiens branched chain keto acid
dehydrogenase E1, alpha polypeptide protein.
Length = 445
Score = 285 bits (699), Expect = 1e-76
Identities = 133/208 (63%), Positives = 158/208 (75%)
Frame = +2
Query: 140 EFPGARAPYVSEMKFFNETSYEPIPIYRVMDNNGQIIDKNEEPNLDKATLINMYKTMVQL 319
+FPGA A ++ +++F IPIYRVMD GQII+ +E+P+L K ++ +YK+M L
Sbjct: 53 QFPGASAEFIDKLEFIQPNVISGIPIYRVMDRQGQIINPSEDPHLPKEKVLKLYKSMTLL 112
Query: 320 SHMDKILYESQRQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVT 499
+ MD+ILYESQRQGRISFYMTNYGEEG H+GSA+AL DLVF QYRE GV +YR +
Sbjct: 113 NTMDRILYESQRQGRISFYMTNYGEEGTHVGSAAALDNTDLVFGQYREAGVLMYRDYPLE 172
Query: 500 ELVNQCYGNCEDPGKGRQMPVHYGSKHHNMVTISSPLGTQMPQAVGAAYAYKRVPNNDRC 679
+ QCYGN D GKGRQMPVHYG K + VTISSPL TQ+PQAVGAAYA KR N +R
Sbjct: 173 LFMAQCYGNISDLGKGRQMPVHYGCKERHFVTISSPLATQIPQAVGAAYAAKRA-NANRV 231
Query: 680 VICYFGDGAASEGDAHAAFNFAATLXCP 763
VICYFG+GAASEGDAHA FNFAATL CP
Sbjct: 232 VICYFGEGAASEGDAHAGFNFAATLECP 259
>AB209828-1|BAD93065.1| 444|Homo sapiens branched chain keto acid
dehydrogenase E1, alpha polypeptide variant protein.
Length = 444
Score = 285 bits (699), Expect = 1e-76
Identities = 133/208 (63%), Positives = 158/208 (75%)
Frame = +2
Query: 140 EFPGARAPYVSEMKFFNETSYEPIPIYRVMDNNGQIIDKNEEPNLDKATLINMYKTMVQL 319
+FPGA A ++ +++F IPIYRVMD GQII+ +E+P+L K ++ +YK+M L
Sbjct: 53 QFPGASAEFIDKLEFIQPNVISGIPIYRVMDRQGQIINPSEDPHLPKEKVLKLYKSMTLL 112
Query: 320 SHMDKILYESQRQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVT 499
+ MD+ILYESQRQGRISFYMTNYGEEG H+GSA+AL DLVF QYRE GV +YR +
Sbjct: 113 NTMDRILYESQRQGRISFYMTNYGEEGTHVGSAAALDNTDLVFGQYREAGVLMYRDYPLE 172
Query: 500 ELVNQCYGNCEDPGKGRQMPVHYGSKHHNMVTISSPLGTQMPQAVGAAYAYKRVPNNDRC 679
+ QCYGN D GKGRQMPVHYG K + VTISSPL TQ+PQAVGAAYA KR N +R
Sbjct: 173 LFMAQCYGNISDLGKGRQMPVHYGCKERHFVTISSPLATQIPQAVGAAYAAKRA-NANRV 231
Query: 680 VICYFGDGAASEGDAHAAFNFAATLXCP 763
VICYFG+GAASEGDAHA FNFAATL CP
Sbjct: 232 VICYFGEGAASEGDAHAGFNFAATLECP 259
>AK127598-1|BAC87051.1| 479|Homo sapiens 1.2.4.4). protein.
Length = 479
Score = 284 bits (696), Expect = 3e-76
Identities = 133/208 (63%), Positives = 157/208 (75%)
Frame = +2
Query: 140 EFPGARAPYVSEMKFFNETSYEPIPIYRVMDNNGQIIDKNEEPNLDKATLINMYKTMVQL 319
+FPGA A ++ +++F IPIYRVMD GQII+ +E+P+L K ++ +YK+M L
Sbjct: 87 QFPGASAEFIDKLEFIQPNVISGIPIYRVMDRQGQIINPSEDPHLPKEKVLKLYKSMTLL 146
Query: 320 SHMDKILYESQRQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVT 499
+ MD+ILYESQRQGRISFYMTNYGEEG H+GSA+AL DLVF QYRE GV +YR +
Sbjct: 147 NTMDRILYESQRQGRISFYMTNYGEEGTHVGSAAALDNTDLVFGQYREAGVLMYRDYPLE 206
Query: 500 ELVNQCYGNCEDPGKGRQMPVHYGSKHHNMVTISSPLGTQMPQAVGAAYAYKRVPNNDRC 679
+ QCYGN D GKGRQMPVHYG K + VTISSPL TQ+PQAVGAAYA KR N +R
Sbjct: 207 LFMAQCYGNISDLGKGRQMPVHYGCKERHFVTISSPLATQIPQAVGAAYAAKRA-NANRV 265
Query: 680 VICYFGDGAASEGDAHAAFNFAATLXCP 763
VICYFG GAASEGDAHA FNFAATL CP
Sbjct: 266 VICYFGGGAASEGDAHAGFNFAATLECP 293
>M22221-1|AAA35590.1| 378|Homo sapiens protein ( Human
branched-chain alpha-keto acid dehydrogenase E1-alpha
subunit (BCKDH) mRNA, partial cds. ).
Length = 378
Score = 268 bits (656), Expect = 2e-71
Identities = 126/185 (68%), Positives = 145/185 (78%)
Frame = +2
Query: 209 IPIYRVMDNNGQIIDKNEEPNLDKATLINMYKTMVQLSHMDKILYESQRQGRISFYMTNY 388
IPIYRVMD GQII+ +E+P+L K ++ +YK+M L+ MD+ILYESQRQGRISFYMTNY
Sbjct: 9 IPIYRVMDRQGQIINPSEDPHLPKEKVLKLYKSMTLLNTMDRILYESQRQGRISFYMTNY 68
Query: 389 GEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTELVNQCYGNCEDPGKGRQMPVHY 568
GEEG H+GSA+AL DLVF QYRE GV +YR + + QCYGN D GKGRQMPVHY
Sbjct: 69 GEEGTHVGSAAALDNTDLVFGQYREAGVLMYRDYPLELFMAQCYGNISDLGKGRQMPVHY 128
Query: 569 GSKHHNMVTISSPLGTQMPQAVGAAYAYKRVPNNDRCVICYFGDGAASEGDAHAAFNFAA 748
G K + VTISSPL TQ+PQAVGAAYA KR N +R VICYFG+GAASEGDAH FNFAA
Sbjct: 129 GCKERHFVTISSPLATQIPQAVGAAYAAKRA-NANRVVICYFGEGAASEGDAHDGFNFAA 187
Query: 749 TLXCP 763
TL CP
Sbjct: 188 TLECP 192
>M86808-1|AAA60232.1| 388|Homo sapiens pyruvate dehydrogenase
complex protein.
Length = 388
Score = 67.7 bits (158), Expect = 4e-11
Identities = 49/165 (29%), Positives = 78/165 (47%), Gaps = 1/165 (0%)
Frame = +2
Query: 272 LDKATLINMYKTMVQLSHMDKILYESQRQGRI-SFYMTNYGEEGIHIGSASALSPKDLVF 448
L +A + Y+ M+ + M+ + +Q I F G+E +G + ++P D V
Sbjct: 54 LTRAEGLKYYRMMLTVRRMELKADQLYKQKFIRGFCHLCDGQEACCVGLEAGINPSDHVI 113
Query: 449 SQYREVGVFLYRGMTVTELVNQCYGNCEDPGKGRQMPVHYGSKHHNMVTISSPLGTQMPQ 628
+ YR GV RG++V ++ + G KG+ +H +K N + +G Q P
Sbjct: 114 TSYRAHGVCYTRGLSVRSILAELTGRRGGCAKGKGGSMHMYTK--NFYGGNGIVGAQGPL 171
Query: 629 AVGAAYAYKRVPNNDRCVICYFGDGAASEGDAHAAFNFAATLXCP 763
G A A K N++ C+ Y GDGAA++G AFN AA P
Sbjct: 172 GAGIALACKYKGNDEICLTLY-GDGAANQGQIAEAFNMAALWKLP 215
>BC127638-1|AAI27639.1| 388|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 2 protein.
Length = 388
Score = 67.7 bits (158), Expect = 4e-11
Identities = 49/165 (29%), Positives = 78/165 (47%), Gaps = 1/165 (0%)
Frame = +2
Query: 272 LDKATLINMYKTMVQLSHMDKILYESQRQGRI-SFYMTNYGEEGIHIGSASALSPKDLVF 448
L +A + Y+ M+ + M+ + +Q I F G+E +G + ++P D V
Sbjct: 54 LTRAEGLKYYRMMLTVRRMELKADQLYKQKFIRGFCHLCDGQEACCVGLEAGINPSDHVI 113
Query: 449 SQYREVGVFLYRGMTVTELVNQCYGNCEDPGKGRQMPVHYGSKHHNMVTISSPLGTQMPQ 628
+ YR GV RG++V ++ + G KG+ +H +K N + +G Q P
Sbjct: 114 TSYRAHGVCYTRGLSVRSILAELTGRRGGCAKGKGGSMHMYTK--NFYGGNGIVGAQGPL 171
Query: 629 AVGAAYAYKRVPNNDRCVICYFGDGAASEGDAHAAFNFAATLXCP 763
G A A K N++ C+ Y GDGAA++G AFN AA P
Sbjct: 172 GAGIALACKYKGNDEICLTLY-GDGAANQGQIAEAFNMAALWKLP 215
>BC127637-1|AAI27638.1| 388|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 2 protein.
Length = 388
Score = 67.7 bits (158), Expect = 4e-11
Identities = 49/165 (29%), Positives = 78/165 (47%), Gaps = 1/165 (0%)
Frame = +2
Query: 272 LDKATLINMYKTMVQLSHMDKILYESQRQGRI-SFYMTNYGEEGIHIGSASALSPKDLVF 448
L +A + Y+ M+ + M+ + +Q I F G+E +G + ++P D V
Sbjct: 54 LTRAEGLKYYRMMLTVRRMELKADQLYKQKFIRGFCHLCDGQEACCVGLEAGINPSDHVI 113
Query: 449 SQYREVGVFLYRGMTVTELVNQCYGNCEDPGKGRQMPVHYGSKHHNMVTISSPLGTQMPQ 628
+ YR GV RG++V ++ + G KG+ +H +K N + +G Q P
Sbjct: 114 TSYRAHGVCYTRGLSVRSILAELTGRRGGCAKGKGGSMHMYTK--NFYGGNGIVGAQGPL 171
Query: 629 AVGAAYAYKRVPNNDRCVICYFGDGAASEGDAHAAFNFAATLXCP 763
G A A K N++ C+ Y GDGAA++G AFN AA P
Sbjct: 172 GAGIALACKYKGNDEICLTLY-GDGAANQGQIAEAFNMAALWKLP 215
>BC119657-1|AAI19658.1| 388|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 2 protein.
Length = 388
Score = 67.7 bits (158), Expect = 4e-11
Identities = 49/165 (29%), Positives = 78/165 (47%), Gaps = 1/165 (0%)
Frame = +2
Query: 272 LDKATLINMYKTMVQLSHMDKILYESQRQGRI-SFYMTNYGEEGIHIGSASALSPKDLVF 448
L +A + Y+ M+ + M+ + +Q I F G+E +G + ++P D V
Sbjct: 54 LTRAEGLKYYRMMLTVRRMELKADQLYKQKFIRGFCHLCDGQEACCVGLEAGINPSDHVI 113
Query: 449 SQYREVGVFLYRGMTVTELVNQCYGNCEDPGKGRQMPVHYGSKHHNMVTISSPLGTQMPQ 628
+ YR GV RG++V ++ + G KG+ +H +K N + +G Q P
Sbjct: 114 TSYRAHGVCYTRGLSVRSILAELTGRRGGCAKGKGGSMHMYTK--NFYGGNGIVGAQGPL 171
Query: 629 AVGAAYAYKRVPNNDRCVICYFGDGAASEGDAHAAFNFAATLXCP 763
G A A K N++ C+ Y GDGAA++G AFN AA P
Sbjct: 172 GAGIALACKYKGNDEICLTLY-GDGAANQGQIAEAFNMAALWKLP 215
>BC119656-1|AAI19657.1| 388|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 2 protein.
Length = 388
Score = 67.7 bits (158), Expect = 4e-11
Identities = 49/165 (29%), Positives = 78/165 (47%), Gaps = 1/165 (0%)
Frame = +2
Query: 272 LDKATLINMYKTMVQLSHMDKILYESQRQGRI-SFYMTNYGEEGIHIGSASALSPKDLVF 448
L +A + Y+ M+ + M+ + +Q I F G+E +G + ++P D V
Sbjct: 54 LTRAEGLKYYRMMLTVRRMELKADQLYKQKFIRGFCHLCDGQEACCVGLEAGINPSDHVI 113
Query: 449 SQYREVGVFLYRGMTVTELVNQCYGNCEDPGKGRQMPVHYGSKHHNMVTISSPLGTQMPQ 628
+ YR GV RG++V ++ + G KG+ +H +K N + +G Q P
Sbjct: 114 TSYRAHGVCYTRGLSVRSILAELTGRRGGCAKGKGGSMHMYTK--NFYGGNGIVGAQGPL 171
Query: 629 AVGAAYAYKRVPNNDRCVICYFGDGAASEGDAHAAFNFAATLXCP 763
G A A K N++ C+ Y GDGAA++G AFN AA P
Sbjct: 172 GAGIALACKYKGNDEICLTLY-GDGAANQGQIAEAFNMAALWKLP 215
>BC094760-1|AAH94760.1| 407|Homo sapiens PDHA2 protein protein.
Length = 407
Score = 67.7 bits (158), Expect = 4e-11
Identities = 49/165 (29%), Positives = 78/165 (47%), Gaps = 1/165 (0%)
Frame = +2
Query: 272 LDKATLINMYKTMVQLSHMDKILYESQRQGRI-SFYMTNYGEEGIHIGSASALSPKDLVF 448
L +A + Y+ M+ + M+ + +Q I F G+E +G + ++P D V
Sbjct: 73 LTRAEGLKYYRMMLTVRRMELKADQLYKQKFIRGFCHLCDGQEACCVGLEAGINPSDHVI 132
Query: 449 SQYREVGVFLYRGMTVTELVNQCYGNCEDPGKGRQMPVHYGSKHHNMVTISSPLGTQMPQ 628
+ YR GV RG++V ++ + G KG+ +H +K N + +G Q P
Sbjct: 133 TSYRAHGVCYTRGLSVRSILAELTGRRGGCAKGKGGSMHMYTK--NFYGGNGIVGAQGPL 190
Query: 629 AVGAAYAYKRVPNNDRCVICYFGDGAASEGDAHAAFNFAATLXCP 763
G A A K N++ C+ Y GDGAA++G AFN AA P
Sbjct: 191 GAGIALACKYKGNDEICLTLY-GDGAANQGQIAEAFNMAALWKLP 234
>BC030697-1|AAH30697.3| 388|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 2 protein.
Length = 388
Score = 67.7 bits (158), Expect = 4e-11
Identities = 49/165 (29%), Positives = 78/165 (47%), Gaps = 1/165 (0%)
Frame = +2
Query: 272 LDKATLINMYKTMVQLSHMDKILYESQRQGRI-SFYMTNYGEEGIHIGSASALSPKDLVF 448
L +A + Y+ M+ + M+ + +Q I F G+E +G + ++P D V
Sbjct: 54 LTRAEGLKYYRMMLTVRRMELKADQLYKQKFIRGFCHLCDGQEACCVGLEAGINPSDHVI 113
Query: 449 SQYREVGVFLYRGMTVTELVNQCYGNCEDPGKGRQMPVHYGSKHHNMVTISSPLGTQMPQ 628
+ YR GV RG++V ++ + G KG+ +H +K N + +G Q P
Sbjct: 114 TSYRAHGVCYTRGLSVRSILAELTGRRGGCAKGKGGSMHMYTK--NFYGGNGIVGAQGPL 171
Query: 629 AVGAAYAYKRVPNNDRCVICYFGDGAASEGDAHAAFNFAATLXCP 763
G A A K N++ C+ Y GDGAA++G AFN AA P
Sbjct: 172 GAGIALACKYKGNDEICLTLY-GDGAANQGQIAEAFNMAALWKLP 215
>BC066953-1|AAH66953.2| 388|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 2 protein.
Length = 388
Score = 66.1 bits (154), Expect = 1e-10
Identities = 49/165 (29%), Positives = 77/165 (46%), Gaps = 1/165 (0%)
Frame = +2
Query: 272 LDKATLINMYKTMVQLSHMDKILYESQRQGRI-SFYMTNYGEEGIHIGSASALSPKDLVF 448
L +A + Y+ M+ + M+ + +Q I F G+E +G + ++P D V
Sbjct: 54 LTRAEGLKYYRMMLTVRRMELKADQLYKQKFIRGFCHLCDGQEACCVGLEAGINPSDHVI 113
Query: 449 SQYREVGVFLYRGMTVTELVNQCYGNCEDPGKGRQMPVHYGSKHHNMVTISSPLGTQMPQ 628
+ YR GV RG +V ++ + G KG+ +H +K N + +G Q P
Sbjct: 114 TSYRAHGVCYTRGPSVRSILAELTGRRGGCAKGKGGSMHMYTK--NFYGGNGIVGAQGPL 171
Query: 629 AVGAAYAYKRVPNNDRCVICYFGDGAASEGDAHAAFNFAATLXCP 763
G A A K N++ C+ Y GDGAA++G AFN AA P
Sbjct: 172 GAGIALACKYKGNDEICLTLY-GDGAANQGQIAEAFNMAALWKLP 215
>X52710-1|CAA36934.1| 390|Homo sapiens protein ( Human mRNA for
liver pyruvate dehydrogenase (EC 1.2.4.1) E1' subunit.
).
Length = 390
Score = 62.1 bits (144), Expect = 2e-09
Identities = 38/125 (30%), Positives = 62/125 (49%)
Frame = +2
Query: 389 GEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTELVNQCYGNCEDPGKGRQMPVHY 568
G+E +G + ++P D + + YR G RG++V E++ + G KG+ +H
Sbjct: 96 GQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHM 155
Query: 569 GSKHHNMVTISSPLGTQMPQAVGAAYAYKRVPNNDRCVICYFGDGAASEGDAHAAFNFAA 748
+K N + +G Q+P G A A K ++ C+ Y GDGAA++G A+N AA
Sbjct: 156 YAK--NFYGGNGIVGAQVPLGAGIALACKYNGKDEVCLTLY-GDGAANQGQIFEAYNMAA 212
Query: 749 TLXCP 763
P
Sbjct: 213 LWKLP 217
>X52709-1|CAA36933.1| 390|Homo sapiens protein ( Human mRNA for
brain pyruvate dehydrogenase (EC 1.2.4.1). ).
Length = 390
Score = 62.1 bits (144), Expect = 2e-09
Identities = 38/125 (30%), Positives = 62/125 (49%)
Frame = +2
Query: 389 GEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTELVNQCYGNCEDPGKGRQMPVHY 568
G+E +G + ++P D + + YR G RG++V E++ + G KG+ +H
Sbjct: 96 GQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHM 155
Query: 569 GSKHHNMVTISSPLGTQMPQAVGAAYAYKRVPNNDRCVICYFGDGAASEGDAHAAFNFAA 748
+K N + +G Q+P G A A K ++ C+ Y GDGAA++G A+N AA
Sbjct: 156 YAK--NFYGGNGIVGAQVPLGAGIALACKYNGKDEVCLTLY-GDGAANQGQIFEAYNMAA 212
Query: 749 TLXCP 763
P
Sbjct: 213 LWKLP 217
>M27257-1|AAA60051.1| 390|Homo sapiens pyruvate dehydrogenase
E1-alpha subunit protein.
Length = 390
Score = 62.1 bits (144), Expect = 2e-09
Identities = 38/125 (30%), Positives = 62/125 (49%)
Frame = +2
Query: 389 GEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTELVNQCYGNCEDPGKGRQMPVHY 568
G+E +G + ++P D + + YR G RG++V E++ + G KG+ +H
Sbjct: 96 GQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHM 155
Query: 569 GSKHHNMVTISSPLGTQMPQAVGAAYAYKRVPNNDRCVICYFGDGAASEGDAHAAFNFAA 748
+K N + +G Q+P G A A K ++ C+ Y GDGAA++G A+N AA
Sbjct: 156 YAK--NFYGGNGIVGAQVPLGAGIALACKYNGKDEVCLTLY-GDGAANQGQIFEAYNMAA 212
Query: 749 TLXCP 763
P
Sbjct: 213 LWKLP 217
>M24848-1|AAA36533.1| 390|Homo sapiens protein ( Human pyruvate
dehydrogenase alpha subunit mRNA, complete cds. ).
Length = 390
Score = 62.1 bits (144), Expect = 2e-09
Identities = 38/125 (30%), Positives = 62/125 (49%)
Frame = +2
Query: 389 GEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTELVNQCYGNCEDPGKGRQMPVHY 568
G+E +G + ++P D + + YR G RG++V E++ + G KG+ +H
Sbjct: 96 GQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHM 155
Query: 569 GSKHHNMVTISSPLGTQMPQAVGAAYAYKRVPNNDRCVICYFGDGAASEGDAHAAFNFAA 748
+K N + +G Q+P G A A K ++ C+ Y GDGAA++G A+N AA
Sbjct: 156 YAK--NFYGGNGIVGAQVPLGAGIALACKYNGKDEVCLTLY-GDGAANQGQIFEAYNMAA 212
Query: 749 TLXCP 763
P
Sbjct: 213 LWKLP 217
>L13318-1|AAA60227.1| 390|Homo sapiens pyruvate dehydrogenase
E1-alpha subunit protein.
Length = 390
Score = 62.1 bits (144), Expect = 2e-09
Identities = 38/125 (30%), Positives = 62/125 (49%)
Frame = +2
Query: 389 GEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTELVNQCYGNCEDPGKGRQMPVHY 568
G+E +G + ++P D + + YR G RG++V E++ + G KG+ +H
Sbjct: 96 GQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHM 155
Query: 569 GSKHHNMVTISSPLGTQMPQAVGAAYAYKRVPNNDRCVICYFGDGAASEGDAHAAFNFAA 748
+K N + +G Q+P G A A K ++ C+ Y GDGAA++G A+N AA
Sbjct: 156 YAK--NFYGGNGIVGAQVPLGAGIALACKYNGKDEVCLTLY-GDGAANQGQIFEAYNMAA 212
Query: 749 TLXCP 763
P
Sbjct: 213 LWKLP 217
>J03575-1|AAA60050.1| 390|Homo sapiens pyruvate dehydrogenase alpha
subunit protein.
Length = 390
Score = 62.1 bits (144), Expect = 2e-09
Identities = 38/125 (30%), Positives = 62/125 (49%)
Frame = +2
Query: 389 GEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTELVNQCYGNCEDPGKGRQMPVHY 568
G+E +G + ++P D + + YR G RG++V E++ + G KG+ +H
Sbjct: 96 GQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHM 155
Query: 569 GSKHHNMVTISSPLGTQMPQAVGAAYAYKRVPNNDRCVICYFGDGAASEGDAHAAFNFAA 748
+K N + +G Q+P G A A K ++ C+ Y GDGAA++G A+N AA
Sbjct: 156 YAK--NFYGGNGIVGAQVPLGAGIALACKYNGKDEVCLTLY-GDGAANQGQIFEAYNMAA 212
Query: 749 TLXCP 763
P
Sbjct: 213 LWKLP 217
>J03503-1|AAA60055.1| 414|Homo sapiens PDHA1 protein.
Length = 414
Score = 62.1 bits (144), Expect = 2e-09
Identities = 38/125 (30%), Positives = 62/125 (49%)
Frame = +2
Query: 389 GEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTELVNQCYGNCEDPGKGRQMPVHY 568
G+E +G + ++P D + + YR G RG++V E++ + G KG+ +H
Sbjct: 120 GQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHM 179
Query: 569 GSKHHNMVTISSPLGTQMPQAVGAAYAYKRVPNNDRCVICYFGDGAASEGDAHAAFNFAA 748
+K N + +G Q+P G A A K ++ C+ Y GDGAA++G A+N AA
Sbjct: 180 YAK--NFYGGNGIVGAQVPLGAGIALACKYNGKDEVCLTLY-GDGAANQGQIFEAYNMAA 236
Query: 749 TLXCP 763
P
Sbjct: 237 LWKLP 241
>EF590117-1|ABQ59099.1| 428|Homo sapiens mitochondrial PDHA1
protein.
Length = 428
Score = 62.1 bits (144), Expect = 2e-09
Identities = 38/125 (30%), Positives = 62/125 (49%)
Frame = +2
Query: 389 GEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTELVNQCYGNCEDPGKGRQMPVHY 568
G+E +G + ++P D + + YR G RG++V E++ + G KG+ +H
Sbjct: 134 GQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHM 193
Query: 569 GSKHHNMVTISSPLGTQMPQAVGAAYAYKRVPNNDRCVICYFGDGAASEGDAHAAFNFAA 748
+K N + +G Q+P G A A K ++ C+ Y GDGAA++G A+N AA
Sbjct: 194 YAK--NFYGGNGIVGAQVPLGAGIALACKYNGKDEVCLTLY-GDGAANQGQIFEAYNMAA 250
Query: 749 TLXCP 763
P
Sbjct: 251 LWKLP 255
>D90084-1|BAA14121.1| 390|Homo sapiens pyruvate dehydrogenase alpha
subunit protein.
Length = 390
Score = 62.1 bits (144), Expect = 2e-09
Identities = 38/125 (30%), Positives = 62/125 (49%)
Frame = +2
Query: 389 GEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTELVNQCYGNCEDPGKGRQMPVHY 568
G+E +G + ++P D + + YR G RG++V E++ + G KG+ +H
Sbjct: 96 GQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHM 155
Query: 569 GSKHHNMVTISSPLGTQMPQAVGAAYAYKRVPNNDRCVICYFGDGAASEGDAHAAFNFAA 748
+K N + +G Q+P G A A K ++ C+ Y GDGAA++G A+N AA
Sbjct: 156 YAK--NFYGGNGIVGAQVPLGAGIALACKYNGKDEVCLTLY-GDGAANQGQIFEAYNMAA 212
Query: 749 TLXCP 763
P
Sbjct: 213 LWKLP 217
>BC002406-1|AAH02406.1| 390|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 1 protein.
Length = 390
Score = 62.1 bits (144), Expect = 2e-09
Identities = 38/125 (30%), Positives = 62/125 (49%)
Frame = +2
Query: 389 GEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTELVNQCYGNCEDPGKGRQMPVHY 568
G+E +G + ++P D + + YR G RG++V E++ + G KG+ +H
Sbjct: 96 GQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHM 155
Query: 569 GSKHHNMVTISSPLGTQMPQAVGAAYAYKRVPNNDRCVICYFGDGAASEGDAHAAFNFAA 748
+K N + +G Q+P G A A K ++ C+ Y GDGAA++G A+N AA
Sbjct: 156 YAK--NFYGGNGIVGAQVPLGAGIALACKYNGKDEVCLTLY-GDGAANQGQIFEAYNMAA 212
Query: 749 TLXCP 763
P
Sbjct: 213 LWKLP 217
>AL732326-7|CAI41291.1| 390|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 1 protein.
Length = 390
Score = 62.1 bits (144), Expect = 2e-09
Identities = 38/125 (30%), Positives = 62/125 (49%)
Frame = +2
Query: 389 GEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTELVNQCYGNCEDPGKGRQMPVHY 568
G+E +G + ++P D + + YR G RG++V E++ + G KG+ +H
Sbjct: 96 GQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHM 155
Query: 569 GSKHHNMVTISSPLGTQMPQAVGAAYAYKRVPNNDRCVICYFGDGAASEGDAHAAFNFAA 748
+K N + +G Q+P G A A K ++ C+ Y GDGAA++G A+N AA
Sbjct: 156 YAK--NFYGGNGIVGAQVPLGAGIALACKYNGKDEVCLTLY-GDGAANQGQIFEAYNMAA 212
Query: 749 TLXCP 763
P
Sbjct: 213 LWKLP 217
>AK222988-1|BAD96708.1| 390|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 1 variant protein.
Length = 390
Score = 62.1 bits (144), Expect = 2e-09
Identities = 38/125 (30%), Positives = 62/125 (49%)
Frame = +2
Query: 389 GEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTELVNQCYGNCEDPGKGRQMPVHY 568
G+E +G + ++P D + + YR G RG++V E++ + G KG+ +H
Sbjct: 96 GQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHM 155
Query: 569 GSKHHNMVTISSPLGTQMPQAVGAAYAYKRVPNNDRCVICYFGDGAASEGDAHAAFNFAA 748
+K N + +G Q+P G A A K ++ C+ Y GDGAA++G A+N AA
Sbjct: 156 YAK--NFYGGNGIVGAQVPLGAGIALACKYNGKDEVCLTLY-GDGAANQGQIFEAYNMAA 212
Query: 749 TLXCP 763
P
Sbjct: 213 LWKLP 217
>AK222740-1|BAD96460.1| 390|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 1 variant protein.
Length = 390
Score = 62.1 bits (144), Expect = 2e-09
Identities = 38/125 (30%), Positives = 62/125 (49%)
Frame = +2
Query: 389 GEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTELVNQCYGNCEDPGKGRQMPVHY 568
G+E +G + ++P D + + YR G RG++V E++ + G KG+ +H
Sbjct: 96 GQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHM 155
Query: 569 GSKHHNMVTISSPLGTQMPQAVGAAYAYKRVPNNDRCVICYFGDGAASEGDAHAAFNFAA 748
+K N + +G Q+P G A A K ++ C+ Y GDGAA++G A+N AA
Sbjct: 156 YAK--NFYGGNGIVGAQVPLGAGIALACKYNGKDEVCLTLY-GDGAANQGQIFEAYNMAA 212
Query: 749 TLXCP 763
P
Sbjct: 213 LWKLP 217
>AL732326-6|CAI41290.1| 204|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 1 protein.
Length = 204
Score = 44.8 bits (101), Expect = 3e-04
Identities = 29/104 (27%), Positives = 50/104 (48%)
Frame = +2
Query: 392 EEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTELVNQCYGNCEDPGKGRQMPVHYG 571
+E +G + ++P D + + YR G RG++V E++ + G KG+ +H
Sbjct: 104 QEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHMY 163
Query: 572 SKHHNMVTISSPLGTQMPQAVGAAYAYKRVPNNDRCVICYFGDG 703
+K N + +G Q+P G A A K ++ C+ Y GDG
Sbjct: 164 AK--NFYGGNGIVGAQVPLGAGIALACKYNGKDEVCLTLY-GDG 204
>EF576990-1|ABQ58815.1| 261|Homo sapiens PDHA1 protein.
Length = 261
Score = 41.5 bits (93), Expect = 0.003
Identities = 28/91 (30%), Positives = 44/91 (48%)
Frame = +2
Query: 491 TVTELVNQCYGNCEDPGKGRQMPVHYGSKHHNMVTISSPLGTQMPQAVGAAYAYKRVPNN 670
+V E++ + G KG+ +H +K N + +G Q+P G A A K +
Sbjct: 1 SVREILAELTGRKGGCAKGKGGSMHMYAK--NFYGGNGIVGAQVPLGAGIALACKYNGKD 58
Query: 671 DRCVICYFGDGAASEGDAHAAFNFAATLXCP 763
+ C+ Y GDGAA++G A+N AA P
Sbjct: 59 EVCLTLY-GDGAANQGQIFEAYNMAALWKLP 88
>AM746210-1|CAN88919.1| 302|Homo sapiens PDHA1/LOC79064 protein
protein.
Length = 302
Score = 39.5 bits (88), Expect = 0.013
Identities = 21/53 (39%), Positives = 28/53 (52%)
Frame = +2
Query: 605 PLGTQMPQAVGAAYAYKRVPNNDRCVICYFGDGAASEGDAHAAFNFAATLXCP 763
PL Q+P G A A K ++ C+ Y GDGAA++G A+N AA P
Sbjct: 78 PLDAQVPLGAGIALACKYNGKDEVCLTLY-GDGAANQGQIFEAYNMAALWKLP 129
>CR533560-1|CAG38591.1| 626|Homo sapiens DKFZP434L1717 protein.
Length = 626
Score = 35.9 bits (79), Expect = 0.16
Identities = 19/47 (40%), Positives = 23/47 (48%)
Frame = +2
Query: 608 LGTQMPQAVGAAYAYKRVPNNDRCVICYFGDGAASEGDAHAAFNFAA 748
LG + A G AY K + V C GDG +SEG AF FA+
Sbjct: 126 LGQGLGTACGMAYTGKYLDKASYRVFCLMGDGESSEGSVWEAFAFAS 172
>BC142943-1|AAI42944.1| 626|Homo sapiens transketolase-like 2
protein.
Length = 626
Score = 35.9 bits (79), Expect = 0.16
Identities = 19/47 (40%), Positives = 23/47 (48%)
Frame = +2
Query: 608 LGTQMPQAVGAAYAYKRVPNNDRCVICYFGDGAASEGDAHAAFNFAA 748
LG + A G AY K + V C GDG +SEG AF FA+
Sbjct: 126 LGQGLGTACGMAYTGKYLDKASYRVFCLMGDGESSEGSVWEAFAFAS 172
>BC125101-1|AAI25102.1| 626|Homo sapiens transketolase-like 2
protein.
Length = 626
Score = 35.9 bits (79), Expect = 0.16
Identities = 19/47 (40%), Positives = 23/47 (48%)
Frame = +2
Query: 608 LGTQMPQAVGAAYAYKRVPNNDRCVICYFGDGAASEGDAHAAFNFAA 748
LG + A G AY K + V C GDG +SEG AF FA+
Sbjct: 126 LGQGLGTACGMAYTGKYLDKASYRVFCLMGDGESSEGSVWEAFAFAS 172
>BC028707-1|AAH28707.4| 626|Homo sapiens transketolase-like 2
protein.
Length = 626
Score = 35.9 bits (79), Expect = 0.16
Identities = 19/47 (40%), Positives = 23/47 (48%)
Frame = +2
Query: 608 LGTQMPQAVGAAYAYKRVPNNDRCVICYFGDGAASEGDAHAAFNFAA 748
LG + A G AY K + V C GDG +SEG AF FA+
Sbjct: 126 LGQGLGTACGMAYTGKYLDKASYRVFCLMGDGESSEGSVWEAFAFAS 172
>AK057325-1|BAB71427.1| 626|Homo sapiens protein ( Homo sapiens
cDNA FLJ32763 fis, clone TESTI2001827, moderately
similar to TRANSKETOLASE (EC 2.2.1.1). ).
Length = 626
Score = 35.9 bits (79), Expect = 0.16
Identities = 19/47 (40%), Positives = 23/47 (48%)
Frame = +2
Query: 608 LGTQMPQAVGAAYAYKRVPNNDRCVICYFGDGAASEGDAHAAFNFAA 748
LG + A G AY K + V C GDG +SEG AF FA+
Sbjct: 126 LGQGLGTACGMAYTGKYLDKASYRVFCLMGDGESSEGSVWEAFAFAS 172
>L48690-1|AAB59581.1| 390|Homo sapiens pyruvate dehydrogenase
E1-alpha subunit precursor protein.
Length = 390
Score = 34.7 bits (76), Expect = 0.37
Identities = 19/47 (40%), Positives = 25/47 (53%)
Frame = +2
Query: 623 PQAVGAAYAYKRVPNNDRCVICYFGDGAASEGDAHAAFNFAATLXCP 763
P A G A A K ++ C+ Y GDGAA++G A+N AA P
Sbjct: 172 PWAAGIALACKYNGKDEVCLTLY-GDGAANQGQIFEAYNMAALWKLP 217
>AL732326-5|CAI41289.1| 180|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 1 protein.
Length = 180
Score = 34.7 bits (76), Expect = 0.37
Identities = 17/64 (26%), Positives = 33/64 (51%)
Frame = +2
Query: 389 GEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTELVNQCYGNCEDPGKGRQMPVHY 568
G+E +G + ++P D + + YR G RG++V E++ + G KG+ +H
Sbjct: 96 GQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHM 155
Query: 569 GSKH 580
+K+
Sbjct: 156 YAKN 159
>AL732326-4|CAI41288.1| 205|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 1 protein.
Length = 205
Score = 34.7 bits (76), Expect = 0.37
Identities = 17/64 (26%), Positives = 33/64 (51%)
Frame = +2
Query: 389 GEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVTELVNQCYGNCEDPGKGRQMPVHY 568
G+E +G + ++P D + + YR G RG++V E++ + G KG+ +H
Sbjct: 134 GQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHM 193
Query: 569 GSKH 580
+K+
Sbjct: 194 YAKN 197
>X67688-1|CAA47919.1| 623|Homo sapiens transketolase protein.
Length = 623
Score = 31.5 bits (68), Expect = 3.4
Identities = 18/47 (38%), Positives = 20/47 (42%)
Frame = +2
Query: 608 LGTQMPQAVGAAYAYKRVPNNDRCVICYFGDGAASEGDAHAAFNFAA 748
LG + A G AY K V C GDG SEG A FA+
Sbjct: 125 LGQGLGAACGMAYTGKYFDKASYRVYCLLGDGELSEGSVWEAMAFAS 171
>U55017-1|AAA98961.1| 623|Homo sapiens transketolase protein.
Length = 623
Score = 31.5 bits (68), Expect = 3.4
Identities = 18/47 (38%), Positives = 20/47 (42%)
Frame = +2
Query: 608 LGTQMPQAVGAAYAYKRVPNNDRCVICYFGDGAASEGDAHAAFNFAA 748
LG + A G AY K V C GDG SEG A FA+
Sbjct: 125 LGQGLGAACGMAYTGKYFDKASYRVYCLLGDGELSEGSVWEAMAFAS 171
>L12711-1|AAA61222.1| 623|Homo sapiens transketolase protein.
Length = 623
Score = 31.5 bits (68), Expect = 3.4
Identities = 18/47 (38%), Positives = 20/47 (42%)
Frame = +2
Query: 608 LGTQMPQAVGAAYAYKRVPNNDRCVICYFGDGAASEGDAHAAFNFAA 748
LG + A G AY K V C GDG SEG A FA+
Sbjct: 125 LGQGLGAACGMAYTGKYFDKASYRVYCLLGDGELSEGSVWEAMAFAS 171
>BC024026-1|AAH24026.2| 536|Homo sapiens TKT protein protein.
Length = 536
Score = 31.5 bits (68), Expect = 3.4
Identities = 18/47 (38%), Positives = 20/47 (42%)
Frame = +2
Query: 608 LGTQMPQAVGAAYAYKRVPNNDRCVICYFGDGAASEGDAHAAFNFAA 748
LG + A G AY K V C GDG SEG A FA+
Sbjct: 38 LGQGLGAACGMAYTGKYFDKASYRVYCLLGDGELSEGSVWEAMAFAS 84
>BC009970-1|AAH09970.1| 623|Homo sapiens transketolase
(Wernicke-Korsakoff syndrome) protein.
Length = 623
Score = 31.5 bits (68), Expect = 3.4
Identities = 18/47 (38%), Positives = 20/47 (42%)
Frame = +2
Query: 608 LGTQMPQAVGAAYAYKRVPNNDRCVICYFGDGAASEGDAHAAFNFAA 748
LG + A G AY K V C GDG SEG A FA+
Sbjct: 125 LGQGLGAACGMAYTGKYFDKASYRVYCLLGDGELSEGSVWEAMAFAS 171
>AK223614-1|BAD97334.1| 623|Homo sapiens transketolase variant
protein.
Length = 623
Score = 31.5 bits (68), Expect = 3.4
Identities = 18/47 (38%), Positives = 20/47 (42%)
Frame = +2
Query: 608 LGTQMPQAVGAAYAYKRVPNNDRCVICYFGDGAASEGDAHAAFNFAA 748
LG + A G AY K V C GDG SEG A FA+
Sbjct: 125 LGQGLGAACGMAYTGKYFDKASYRVYCLLGDGELSEGSVWEAMAFAS 171
>L23808-1|AAA58658.1| 470|Homo sapiens metalloproteinase protein.
Length = 470
Score = 30.3 bits (65), Expect = 7.9
Identities = 18/82 (21%), Positives = 41/82 (50%), Gaps = 2/82 (2%)
Frame = +2
Query: 320 SHMDKILYESQRQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVT 499
+H D+ + + G + ++T E G +G + PK ++F Y+ V + +R ++
Sbjct: 195 AHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFR-LSAD 253
Query: 500 EL--VNQCYGNCEDPGKGRQMP 559
++ + YG DP + +++P
Sbjct: 254 DIRGIQSLYG---DPKENQRLP 272
>BC112301-1|AAI12302.1| 470|Homo sapiens matrix metalloproteinase
12, preproprotein protein.
Length = 470
Score = 30.3 bits (65), Expect = 7.9
Identities = 18/82 (21%), Positives = 41/82 (50%), Gaps = 2/82 (2%)
Frame = +2
Query: 320 SHMDKILYESQRQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVT 499
+H D+ + + G + ++T E G +G + PK ++F Y+ V + +R ++
Sbjct: 195 AHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFR-LSAD 253
Query: 500 EL--VNQCYGNCEDPGKGRQMP 559
++ + YG DP + +++P
Sbjct: 254 DIRGIQSLYG---DPKENQRLP 272
>AY856072-1|AAW29944.1| 470|Homo sapiens matrix metalloproteinase
12 (macrophage elastase) protein.
Length = 470
Score = 30.3 bits (65), Expect = 7.9
Identities = 18/82 (21%), Positives = 41/82 (50%), Gaps = 2/82 (2%)
Frame = +2
Query: 320 SHMDKILYESQRQGRISFYMTNYGEEGIHIGSASALSPKDLVFSQYREVGVFLYRGMTVT 499
+H D+ + + G + ++T E G +G + PK ++F Y+ V + +R ++
Sbjct: 195 AHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFR-LSAD 253
Query: 500 EL--VNQCYGNCEDPGKGRQMP 559
++ + YG DP + +++P
Sbjct: 254 DIRGIQSLYG---DPKENQRLP 272
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 110,423,579
Number of Sequences: 237096
Number of extensions: 2440810
Number of successful extensions: 8765
Number of sequences better than 10.0: 51
Number of HSP's better than 10.0 without gapping: 8606
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 8734
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 9199990470
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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