Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P10_F_B18
(856 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC039600-1|AAH39600.1| 1049|Homo sapiens hect domain and RLD 4 p... 194 5e-49
AY650033-1|AAV66579.1| 979|Homo sapiens HECT and RCC1 containin... 194 5e-49
AY221963-1|AAO65480.1| 1057|Homo sapiens HECT and RCC1 containin... 194 5e-49
AL356741-3|CAH74148.1| 1049|Homo sapiens hect domain and RLD 4 p... 194 5e-49
AL133551-3|CAI16032.1| 1049|Homo sapiens hect domain and RLD 4 p... 194 5e-49
D25215-1|BAA04945.2| 1054|Homo sapiens KIAA0032 protein. 180 8e-45
BC038960-1|AAH38960.1| 368|Homo sapiens HERC3 protein protein. 179 1e-44
AC098582-1|AAY41038.1| 382|Homo sapiens unknown protein. 179 1e-44
BC042047-1|AAH42047.2| 1022|Homo sapiens hect domain and RLD 6 p... 162 1e-39
AY653203-1|AAV66897.1| 322|Homo sapiens truncated HERC6 protein. 162 1e-39
AY653202-1|AAV66896.1| 364|Homo sapiens truncated HERC6 protein. 162 1e-39
AY653201-1|AAV66895.1| 986|Homo sapiens HERC6 splice variant pr... 162 1e-39
AF336798-1|AAQ14893.1| 1022|Homo sapiens HERC6 protein. 162 1e-39
AB027289-1|BAA88519.1| 1024|Homo sapiens cyclin-E binding protei... 128 2e-29
U50078-1|AAD12586.1| 4861|Homo sapiens p532 protein. 127 4e-29
AY337518-1|AAR00320.1| 1024|Homo sapiens HECT E3 ubiquitin ligas... 127 4e-29
AF071172-1|AAD08657.1| 4834|Homo sapiens HERC2 protein. 126 1e-28
BC029052-1|AAH29052.1| 551|Homo sapiens regulator of chromosome... 125 2e-28
AY341245-1|AAP88928.1| 551|Homo sapiens chromosome condensation... 125 2e-28
AL157813-1|CAH70795.1| 551|Homo sapiens regulator of chromosome... 125 2e-28
AF060219-1|AAC79987.1| 551|Homo sapiens RCC1-like G exchanging ... 125 2e-28
AB209543-1|BAD92780.1| 556|Homo sapiens RCC1-like G exchanging ... 125 2e-28
BC038104-1|AAH38104.1| 355|Homo sapiens RCBTB1 protein protein. 124 3e-28
AL139321-5|CAH71047.1| 531|Homo sapiens regulator of chromosome... 124 3e-28
AK096654-1|BAC04833.1| 531|Homo sapiens protein ( Homo sapiens ... 124 3e-28
AJ319660-1|CAC40027.1| 531|Homo sapiens guanine nucleotide exch... 124 3e-28
AF334406-1|AAK38372.1| 531|Homo sapiens CLLL7 protein protein. 124 3e-28
AF224249-1|AAO27475.1| 328|Homo sapiens HERC2 protein. 122 2e-27
AB046813-1|BAB13419.1| 953|Homo sapiens KIAA1593 protein protein. 122 2e-27
AF225407-1|AAO27483.1| 409|Homo sapiens HERC2 protein. 115 2e-25
AL356741-1|CAH74146.1| 907|Homo sapiens hect domain and RLD 4 p... 107 5e-23
AL133551-1|CAI16031.1| 907|Homo sapiens hect domain and RLD 4 p... 107 5e-23
X97668-1|CAA66258.1| 815|Homo sapiens XLRP3 protein. 106 9e-23
U57629-1|AAC50481.1| 815|Homo sapiens retinitis pigmentosa GTPa... 106 9e-23
BC031624-1|AAH31624.1| 480|Homo sapiens RPGR protein protein. 106 9e-23
AL606748-2|CAI95407.1| 815|Homo sapiens retinitis pigmentosa GT... 106 9e-23
AK223491-1|BAD97211.1| 815|Homo sapiens retinitis pigmentosa GT... 106 9e-23
AJ238395-1|CAB54002.1| 646|Homo sapiens RPGR protein protein. 106 9e-23
AJ318463-1|CAC86116.1| 815|Homo sapiens retinitis pigmentosa GT... 105 2e-22
AK092403-1|BAC03879.1| 184|Homo sapiens protein ( Homo sapiens ... 104 4e-22
AC004460-2|AAC06339.1| 371|Homo sapiens WUGSC:H_DJ1086D14.2 pro... 101 3e-21
BC065375-1|AAH65375.1| 458|Homo sapiens secretion regulating gu... 101 3e-21
AJ243951-1|CAB60833.1| 288|Homo sapiens deafness locus associat... 101 3e-21
AJ243950-1|CAB60832.1| 458|Homo sapiens deafness locus associat... 101 3e-21
BC142946-1|AAI42947.1| 457|Homo sapiens RCC2 protein protein. 97 5e-20
BC053908-1|AAH53908.1| 522|Homo sapiens RCC2 protein protein. 97 5e-20
BC042141-1|AAH42141.1| 522|Homo sapiens regulator of chromosome... 97 5e-20
AL359612-1|CAB94882.1| 333|Homo sapiens hypothetical protein pr... 97 5e-20
AJ421269-1|CAD13148.1| 522|Homo sapiens RCC1-like protein protein. 97 5e-20
AB040903-1|BAA95994.1| 564|Homo sapiens KIAA1470 protein protein. 97 5e-20
BC113705-1|AAI13706.1| 692|Homo sapiens NIMA (never in mitosis ... 93 9e-19
BC112240-1|AAI12241.1| 692|Homo sapiens NIMA-related kinase 8 p... 93 9e-19
AY267371-1|AAP04006.1| 692|Homo sapiens NIMA-family kinase NEK8... 93 9e-19
AY242354-1|AAO88243.1| 692|Homo sapiens NIMA-related kinase 12a... 93 9e-19
BC004933-1|AAH04933.1| 351|Homo sapiens RCC2 protein protein. 87 1e-16
BC112101-1|AAI12102.1| 979|Homo sapiens NIMA related kinase 9 p... 86 1e-16
BC093881-1|AAH93881.1| 979|Homo sapiens NIMA (never in mitosis ... 86 1e-16
AY080896-1|AAL87410.1| 979|Homo sapiens NIMA-family kinase NERC... 86 1e-16
AY048580-1|AAL05428.1| 979|Homo sapiens NIMA-related kinase Nek... 86 1e-16
AC007055-4|AAD31939.1| 414|Homo sapiens protein ( Homo sapiens ... 86 1e-16
AB082526-1|BAC02704.1| 1011|Homo sapiens KIAA1995 protein protein. 86 1e-16
X12654-1|CAA31182.1| 421|Homo sapiens protein ( Human mRNA for ... 85 3e-16
X06130-1|CAA29496.1| 421|Homo sapiens protein ( Human mRNA for ... 85 3e-16
D00591-1|BAA00469.1| 421|Homo sapiens RCC1 protein. 85 3e-16
CR407693-1|CAG28621.1| 421|Homo sapiens CHC1 protein. 85 3e-16
BC069198-1|AAH69198.1| 452|Homo sapiens regulator of chromosome... 85 3e-16
BC036903-1|AAH36903.1| 421|Homo sapiens regulator of chromosome... 85 3e-16
BC010067-1|AAH10067.1| 421|Homo sapiens regulator of chromosome... 85 3e-16
BC007300-1|AAH07300.1| 421|Homo sapiens regulator of chromosome... 85 3e-16
AL513497-2|CAI22287.1| 421|Homo sapiens regulator of chromosome... 85 3e-16
AF498924-1|AAM21072.1| 421|Homo sapiens regulator of chromosome... 85 3e-16
BC032712-1|AAH32712.1| 454|Homo sapiens WBSCR16 protein protein. 83 2e-15
BC019008-1|AAH19008.1| 464|Homo sapiens Williams-Beuren syndrom... 83 2e-15
BC007823-1|AAH07823.1| 464|Homo sapiens Williams-Beuren syndrom... 83 2e-15
AF410455-1|AAM62304.1| 464|Homo sapiens RCC1-like G exchanging ... 83 2e-15
BC040929-1|AAH40929.1| 651|Homo sapiens HERC1 protein protein. 81 5e-15
DQ005634-1|AAY55907.1| 1196|Homo sapiens inhibitor of Bruton's t... 73 2e-12
DQ005633-1|AAY55906.1| 1353|Homo sapiens inhibitor of Bruton's t... 73 2e-12
BC113698-1|AAI13699.1| 1353|Homo sapiens inhibitor of Bruton aga... 73 2e-12
BC113696-1|AAI13697.1| 1353|Homo sapiens inhibitor of Bruton aga... 73 2e-12
AL050333-2|CAI23416.1| 1187|Homo sapiens RP1-93K22.1 protein. 73 2e-12
AB037838-1|BAA92655.2| 1379|Homo sapiens KIAA1417 protein protein. 73 2e-12
BC040695-1|AAH40695.1| 358|Homo sapiens WBSCR16 protein protein. 71 4e-12
BC071576-1|AAH71576.1| 1237|Homo sapiens ALS2 protein protein. 71 7e-12
AK023024-1|BAB14362.1| 396|Homo sapiens protein ( Homo sapiens ... 71 7e-12
AF391100-1|AAL14103.1| 1657|Homo sapiens alsin protein. 71 7e-12
AB053306-1|BAB69015.1| 396|Homo sapiens ALS2 protein. 71 7e-12
AB053305-1|BAB69014.1| 1657|Homo sapiens ALS2 protein. 71 7e-12
AB046783-1|BAB13389.2| 1658|Homo sapiens KIAA1563 protein protein. 71 7e-12
BC029174-1|AAH29174.1| 812|Homo sapiens ALS2 protein protein. 70 1e-11
AL359257-2|CAI39759.1| 4640|Homo sapiens AC001226.5 protein. 68 5e-11
AL159158-1|CAI16842.1| 4640|Homo sapiens AC001226.5 protein. 68 5e-11
AL159154-1|CAH73736.1| 4640|Homo sapiens AC001226.5 protein. 68 5e-11
AF075587-1|AAC39928.1| 4641|Homo sapiens protein associated with... 68 5e-11
AC007279-1|AAY15058.1| 1598|Homo sapiens unknown protein. 65 3e-10
AY650032-1|AAV66578.1| 117|Homo sapiens HECT and RCC1 containin... 57 9e-08
AY650034-1|AAV66580.1| 110|Homo sapiens HECT and RCC1 containin... 56 2e-07
AF225404-1|AAO27482.1| 259|Homo sapiens HERC2 protein. 51 6e-06
BC113826-1|AAI13827.1| 244|Homo sapiens RCCD1 protein protein. 50 8e-06
BC067293-1|AAH67293.1| 580|Homo sapiens F-box protein 24 protein. 35 0.43
AC069281-1|AAP21863.1| 580|Homo sapiens unknown protein. 35 0.43
BC151230-1|AAI51231.1| 1411|Homo sapiens KIAA0329 protein. 32 3.1
BC142715-1|AAI42716.1| 1267|Homo sapiens KIAA0329 protein protein. 32 3.1
BC142667-1|AAI42668.1| 1267|Homo sapiens KIAA0329 protein protein. 32 3.1
AB002327-1|BAA20787.2| 1417|Homo sapiens KIAA0329 protein. 32 3.1
AB002295-1|BAA20757.1| 1271|Homo sapiens KIAA0297 protein. 32 3.1
>BC039600-1|AAH39600.1| 1049|Homo sapiens hect domain and RLD 4
protein.
Length = 1049
Score = 194 bits (472), Expect = 5e-49
Identities = 91/227 (40%), Positives = 139/227 (61%)
Frame = +3
Query: 174 MFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCG 353
M CWGNA+ +L + G ++V++P S + + ++ V G H++++ + G +Y+CG
Sbjct: 1 MLCWGNASFGQLGLGGID-EEIVLEPRKSDFFINKRVRDVGCGLRHTVFVLDDGTVYTCG 59
Query: 354 NNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQL 533
ND+GQLG + K P V I ++CG H+LA+++ GQ ++WG DS GQL
Sbjct: 60 CNDLGQLGHEKSR---KKPEQVVALDAQNIVAVSCGEAHTLALNDKGQVYAWGLDSDGQL 116
Query: 534 GNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTISN 713
G P+ +K L+ ++QVACG YHS+AL+ + +++ WG N YGQ GLGT
Sbjct: 117 GLVGSEECIRVPRNIKSLSDIQIVQVACGYYHSLALSKASEVFCWGQNKYGQLGLGTDCK 176
Query: 714 KEMSPQHISSLIGVPIALIACGNNHTFVLSKSGAVFGWGKNTHGXLG 854
K+ SPQ + SL+G+P +A G H+FVL+ SGA+FGWG+N G LG
Sbjct: 177 KQTSPQLLKSLLGIPFMQVAAGGAHSFVLTLSGAIFGWGRNKFGQLG 223
Score = 139 bits (336), Expect = 1e-32
Identities = 72/195 (36%), Positives = 103/195 (52%)
Frame = +3
Query: 270 ESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTIST 449
++ +I AV+ GE H+L L++ G +Y+ G + GQLG + + P +++ D I
Sbjct: 82 DAQNIVAVSCGEAHTLALNDKGQVYAWGLDSDGQLGLVGSEECIRVPRNIKSLSDIQIVQ 141
Query: 450 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 629
+ACG HSLA+ + + F WG + GQLG Q P+ +K L +QVA G H
Sbjct: 142 VACGYYHSLALSKASEVFCWGQNKYGQLGLGTDCKKQTSPQLLKSLLGIPFMQVAAGGAH 201
Query: 630 SVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFVLSKS 809
S LT SG ++ WG N +GQ GL N P + SL I I CG +HT L+K
Sbjct: 202 SFVLTLSGAIFGWGRNKFGQLGLND-ENDRYVPNLLKSLRSQKIVYICCGEDHTAALTKE 260
Query: 810 GAVFGWGKNTHGXLG 854
G VF +G +G LG
Sbjct: 261 GGVFTFGAGGYGQLG 275
Score = 128 bits (308), Expect = 3e-29
Identities = 72/234 (30%), Positives = 120/234 (51%), Gaps = 1/234 (0%)
Frame = +3
Query: 156 LQNYKKMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSG 335
L + +++ WG + +L + GS+ + + P K I VA G +HSL LS +
Sbjct: 99 LNDKGQVYAWGLDSDGQLGLVGSE--ECIRVPRNIKSLSDIQIVQVACGYYHSLALSKAS 156
Query: 336 HLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGS 515
++ G N GQLG T+ +P L+++ +A G HS + G F WG
Sbjct: 157 EVFCWGQNKYGQLGLGTDCKKQTSPQLLKSLLGIPFMQVAAGGAHSFVLTLSGAIFGWGR 216
Query: 516 DSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCG 695
+ GQLG N + + P +K L ++ ++ + CG H+ ALT G ++++GA YGQ G
Sbjct: 217 NKFGQLGLN-DENDRYVPNLLKSLRSQKIVYICCGEDHTAALTKEGGVFTFGAGGYGQLG 275
Query: 696 LGTISNKEMSPQHISSLIGVPIALIACGNNHTFV-LSKSGAVFGWGKNTHGXLG 854
+ S+ E++P+ + L+G + IACG HT + SG ++ +G +G LG
Sbjct: 276 HNSTSH-EINPRKVFELMGSIVTEIACGRQHTSAFVPSSGRIYSFGLGGNGQLG 328
Score = 100 bits (240), Expect = 6e-21
Identities = 64/189 (33%), Positives = 97/189 (51%), Gaps = 1/189 (0%)
Frame = +3
Query: 156 LQNYKKMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSG 335
L ++FCWG + +L + G+ P L K VAAG HS L+ SG
Sbjct: 152 LSKASEVFCWGQNKYGQLGL-GTDCKKQT-SPQLLKSLLGIPFMQVAAGGAHSFVLTLSG 209
Query: 336 HLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGS 515
++ G N GQLG E+D P L+++ + I I CG H+ A+ + G F++G+
Sbjct: 210 AIFGWGRNKFGQLGLNDENDRYV-PNLLKSLRSQKIVYICCGEDHTAALTKEGGVFTFGA 268
Query: 516 DSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALT-NSGDLYSWGANSYGQC 692
GQLG+N +H + P+ V L V ++ACG H+ A +SG +YS+G GQ
Sbjct: 269 GGYGQLGHNSTSH-EINPRKVFELMGSIVTEIACGRQHTSAFVPSSGRIYSFGLGGNGQL 327
Query: 693 GLGTISNKE 719
G G+ SN++
Sbjct: 328 GTGSTSNRK 336
>AY650033-1|AAV66579.1| 979|Homo sapiens HECT and RCC1 containing
protein 4 isoform 3 protein.
Length = 979
Score = 194 bits (472), Expect = 5e-49
Identities = 91/227 (40%), Positives = 139/227 (61%)
Frame = +3
Query: 174 MFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCG 353
M CWGNA+ +L + G ++V++P S + + ++ V G H++++ + G +Y+CG
Sbjct: 1 MLCWGNASFGQLGLGGID-EEIVLEPRKSDFFINKRVRDVGCGLRHTVFVLDDGTVYTCG 59
Query: 354 NNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQL 533
ND+GQLG + K P V I ++CG H+LA+++ GQ ++WG DS GQL
Sbjct: 60 CNDLGQLGHEKSR---KKPEQVVALDAQNIVAVSCGEAHTLALNDKGQVYAWGLDSDGQL 116
Query: 534 GNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTISN 713
G P+ +K L+ ++QVACG YHS+AL+ + +++ WG N YGQ GLGT
Sbjct: 117 GLVGSEECIRVPRNIKSLSDIQIVQVACGYYHSLALSKASEVFCWGQNKYGQLGLGTDCK 176
Query: 714 KEMSPQHISSLIGVPIALIACGNNHTFVLSKSGAVFGWGKNTHGXLG 854
K+ SPQ + SL+G+P +A G H+FVL+ SGA+FGWG+N G LG
Sbjct: 177 KQTSPQLLKSLLGIPFMQVAAGGAHSFVLTLSGAIFGWGRNKFGQLG 223
Score = 139 bits (336), Expect = 1e-32
Identities = 72/195 (36%), Positives = 103/195 (52%)
Frame = +3
Query: 270 ESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTIST 449
++ +I AV+ GE H+L L++ G +Y+ G + GQLG + + P +++ D I
Sbjct: 82 DAQNIVAVSCGEAHTLALNDKGQVYAWGLDSDGQLGLVGSEECIRVPRNIKSLSDIQIVQ 141
Query: 450 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 629
+ACG HSLA+ + + F WG + GQLG Q P+ +K L +QVA G H
Sbjct: 142 VACGYYHSLALSKASEVFCWGQNKYGQLGLGTDCKKQTSPQLLKSLLGIPFMQVAAGGAH 201
Query: 630 SVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFVLSKS 809
S LT SG ++ WG N +GQ GL N P + SL I I CG +HT L+K
Sbjct: 202 SFVLTLSGAIFGWGRNKFGQLGLND-ENDRYVPNLLKSLRSQKIVYICCGEDHTAALTKE 260
Query: 810 GAVFGWGKNTHGXLG 854
G VF +G +G LG
Sbjct: 261 GGVFTFGAGGYGQLG 275
Score = 128 bits (308), Expect = 3e-29
Identities = 72/234 (30%), Positives = 120/234 (51%), Gaps = 1/234 (0%)
Frame = +3
Query: 156 LQNYKKMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSG 335
L + +++ WG + +L + GS+ + + P K I VA G +HSL LS +
Sbjct: 99 LNDKGQVYAWGLDSDGQLGLVGSE--ECIRVPRNIKSLSDIQIVQVACGYYHSLALSKAS 156
Query: 336 HLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGS 515
++ G N GQLG T+ +P L+++ +A G HS + G F WG
Sbjct: 157 EVFCWGQNKYGQLGLGTDCKKQTSPQLLKSLLGIPFMQVAAGGAHSFVLTLSGAIFGWGR 216
Query: 516 DSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCG 695
+ GQLG N + + P +K L ++ ++ + CG H+ ALT G ++++GA YGQ G
Sbjct: 217 NKFGQLGLN-DENDRYVPNLLKSLRSQKIVYICCGEDHTAALTKEGGVFTFGAGGYGQLG 275
Query: 696 LGTISNKEMSPQHISSLIGVPIALIACGNNHTFV-LSKSGAVFGWGKNTHGXLG 854
+ S+ E++P+ + L+G + IACG HT + SG ++ +G +G LG
Sbjct: 276 HNSTSH-EINPRKVFELMGSIVTEIACGRQHTSAFVPSSGRIYSFGLGGNGQLG 328
Score = 100 bits (240), Expect = 6e-21
Identities = 64/189 (33%), Positives = 97/189 (51%), Gaps = 1/189 (0%)
Frame = +3
Query: 156 LQNYKKMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSG 335
L ++FCWG + +L + G+ P L K VAAG HS L+ SG
Sbjct: 152 LSKASEVFCWGQNKYGQLGL-GTDCKKQT-SPQLLKSLLGIPFMQVAAGGAHSFVLTLSG 209
Query: 336 HLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGS 515
++ G N GQLG E+D P L+++ + I I CG H+ A+ + G F++G+
Sbjct: 210 AIFGWGRNKFGQLGLNDENDRYV-PNLLKSLRSQKIVYICCGEDHTAALTKEGGVFTFGA 268
Query: 516 DSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALT-NSGDLYSWGANSYGQC 692
GQLG+N +H + P+ V L V ++ACG H+ A +SG +YS+G GQ
Sbjct: 269 GGYGQLGHNSTSH-EINPRKVFELMGSIVTEIACGRQHTSAFVPSSGRIYSFGLGGNGQL 327
Query: 693 GLGTISNKE 719
G G+ SN++
Sbjct: 328 GTGSTSNRK 336
>AY221963-1|AAO65480.1| 1057|Homo sapiens HECT and RCC1 containing
protein 4 isoform 1 protein.
Length = 1057
Score = 194 bits (472), Expect = 5e-49
Identities = 91/227 (40%), Positives = 139/227 (61%)
Frame = +3
Query: 174 MFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCG 353
M CWGNA+ +L + G ++V++P S + + ++ V G H++++ + G +Y+CG
Sbjct: 1 MLCWGNASFGQLGLGGID-EEIVLEPRKSDFFINKRVRDVGCGLRHTVFVLDDGTVYTCG 59
Query: 354 NNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQL 533
ND+GQLG + K P V I ++CG H+LA+++ GQ ++WG DS GQL
Sbjct: 60 CNDLGQLGHEKSR---KKPEQVVALDAQNIVAVSCGEAHTLALNDKGQVYAWGLDSDGQL 116
Query: 534 GNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTISN 713
G P+ +K L+ ++QVACG YHS+AL+ + +++ WG N YGQ GLGT
Sbjct: 117 GLVGSEECIRVPRNIKSLSDIQIVQVACGYYHSLALSKASEVFCWGQNKYGQLGLGTDCK 176
Query: 714 KEMSPQHISSLIGVPIALIACGNNHTFVLSKSGAVFGWGKNTHGXLG 854
K+ SPQ + SL+G+P +A G H+FVL+ SGA+FGWG+N G LG
Sbjct: 177 KQTSPQLLKSLLGIPFMQVAAGGAHSFVLTLSGAIFGWGRNKFGQLG 223
Score = 139 bits (336), Expect = 1e-32
Identities = 72/195 (36%), Positives = 103/195 (52%)
Frame = +3
Query: 270 ESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTIST 449
++ +I AV+ GE H+L L++ G +Y+ G + GQLG + + P +++ D I
Sbjct: 82 DAQNIVAVSCGEAHTLALNDKGQVYAWGLDSDGQLGLVGSEECIRVPRNIKSLSDIQIVQ 141
Query: 450 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 629
+ACG HSLA+ + + F WG + GQLG Q P+ +K L +QVA G H
Sbjct: 142 VACGYYHSLALSKASEVFCWGQNKYGQLGLGTDCKKQTSPQLLKSLLGIPFMQVAAGGAH 201
Query: 630 SVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFVLSKS 809
S LT SG ++ WG N +GQ GL N P + SL I I CG +HT L+K
Sbjct: 202 SFVLTLSGAIFGWGRNKFGQLGLND-ENDRYVPNLLKSLRSQKIVYICCGEDHTAALTKE 260
Query: 810 GAVFGWGKNTHGXLG 854
G VF +G +G LG
Sbjct: 261 GGVFTFGAGGYGQLG 275
Score = 128 bits (308), Expect = 3e-29
Identities = 72/234 (30%), Positives = 120/234 (51%), Gaps = 1/234 (0%)
Frame = +3
Query: 156 LQNYKKMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSG 335
L + +++ WG + +L + GS+ + + P K I VA G +HSL LS +
Sbjct: 99 LNDKGQVYAWGLDSDGQLGLVGSE--ECIRVPRNIKSLSDIQIVQVACGYYHSLALSKAS 156
Query: 336 HLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGS 515
++ G N GQLG T+ +P L+++ +A G HS + G F WG
Sbjct: 157 EVFCWGQNKYGQLGLGTDCKKQTSPQLLKSLLGIPFMQVAAGGAHSFVLTLSGAIFGWGR 216
Query: 516 DSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCG 695
+ GQLG N + + P +K L ++ ++ + CG H+ ALT G ++++GA YGQ G
Sbjct: 217 NKFGQLGLN-DENDRYVPNLLKSLRSQKIVYICCGEDHTAALTKEGGVFTFGAGGYGQLG 275
Query: 696 LGTISNKEMSPQHISSLIGVPIALIACGNNHTFV-LSKSGAVFGWGKNTHGXLG 854
+ S+ E++P+ + L+G + IACG HT + SG ++ +G +G LG
Sbjct: 276 HNSTSH-EINPRKVFELMGSIVTEIACGRQHTSAFVPSSGRIYSFGLGGNGQLG 328
Score = 100 bits (240), Expect = 6e-21
Identities = 64/189 (33%), Positives = 97/189 (51%), Gaps = 1/189 (0%)
Frame = +3
Query: 156 LQNYKKMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSG 335
L ++FCWG + +L + G+ P L K VAAG HS L+ SG
Sbjct: 152 LSKASEVFCWGQNKYGQLGL-GTDCKKQT-SPQLLKSLLGIPFMQVAAGGAHSFVLTLSG 209
Query: 336 HLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGS 515
++ G N GQLG E+D P L+++ + I I CG H+ A+ + G F++G+
Sbjct: 210 AIFGWGRNKFGQLGLNDENDRYV-PNLLKSLRSQKIVYICCGEDHTAALTKEGGVFTFGA 268
Query: 516 DSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALT-NSGDLYSWGANSYGQC 692
GQLG+N +H + P+ V L V ++ACG H+ A +SG +YS+G GQ
Sbjct: 269 GGYGQLGHNSTSH-EINPRKVFELMGSIVTEIACGRQHTSAFVPSSGRIYSFGLGGNGQL 327
Query: 693 GLGTISNKE 719
G G+ SN++
Sbjct: 328 GTGSTSNRK 336
>AL356741-3|CAH74148.1| 1049|Homo sapiens hect domain and RLD 4
protein.
Length = 1049
Score = 194 bits (472), Expect = 5e-49
Identities = 91/227 (40%), Positives = 139/227 (61%)
Frame = +3
Query: 174 MFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCG 353
M CWGNA+ +L + G ++V++P S + + ++ V G H++++ + G +Y+CG
Sbjct: 1 MLCWGNASFGQLGLGGID-EEIVLEPRKSDFFINKRVRDVGCGLRHTVFVLDDGTVYTCG 59
Query: 354 NNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQL 533
ND+GQLG + K P V I ++CG H+LA+++ GQ ++WG DS GQL
Sbjct: 60 CNDLGQLGHEKSR---KKPEQVVALDAQNIVAVSCGEAHTLALNDKGQVYAWGLDSDGQL 116
Query: 534 GNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTISN 713
G P+ +K L+ ++QVACG YHS+AL+ + +++ WG N YGQ GLGT
Sbjct: 117 GLVGSEECIRVPRNIKSLSDIQIVQVACGYYHSLALSKASEVFCWGQNKYGQLGLGTDCK 176
Query: 714 KEMSPQHISSLIGVPIALIACGNNHTFVLSKSGAVFGWGKNTHGXLG 854
K+ SPQ + SL+G+P +A G H+FVL+ SGA+FGWG+N G LG
Sbjct: 177 KQTSPQLLKSLLGIPFMQVAAGGAHSFVLTLSGAIFGWGRNKFGQLG 223
Score = 139 bits (336), Expect = 1e-32
Identities = 72/195 (36%), Positives = 103/195 (52%)
Frame = +3
Query: 270 ESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTIST 449
++ +I AV+ GE H+L L++ G +Y+ G + GQLG + + P +++ D I
Sbjct: 82 DAQNIVAVSCGEAHTLALNDKGQVYAWGLDSDGQLGLVGSEECIRVPRNIKSLSDIQIVQ 141
Query: 450 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 629
+ACG HSLA+ + + F WG + GQLG Q P+ +K L +QVA G H
Sbjct: 142 VACGYYHSLALSKASEVFCWGQNKYGQLGLGTDCKKQTSPQLLKSLLGIPFMQVAAGGAH 201
Query: 630 SVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFVLSKS 809
S LT SG ++ WG N +GQ GL N P + SL I I CG +HT L+K
Sbjct: 202 SFVLTLSGAIFGWGRNKFGQLGLND-ENDRYVPNLLKSLRSQKIVYICCGEDHTAALTKE 260
Query: 810 GAVFGWGKNTHGXLG 854
G VF +G +G LG
Sbjct: 261 GGVFTFGAGGYGQLG 275
Score = 128 bits (308), Expect = 3e-29
Identities = 72/234 (30%), Positives = 120/234 (51%), Gaps = 1/234 (0%)
Frame = +3
Query: 156 LQNYKKMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSG 335
L + +++ WG + +L + GS+ + + P K I VA G +HSL LS +
Sbjct: 99 LNDKGQVYAWGLDSDGQLGLVGSE--ECIRVPRNIKSLSDIQIVQVACGYYHSLALSKAS 156
Query: 336 HLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGS 515
++ G N GQLG T+ +P L+++ +A G HS + G F WG
Sbjct: 157 EVFCWGQNKYGQLGLGTDCKKQTSPQLLKSLLGIPFMQVAAGGAHSFVLTLSGAIFGWGR 216
Query: 516 DSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCG 695
+ GQLG N + + P +K L ++ ++ + CG H+ ALT G ++++GA YGQ G
Sbjct: 217 NKFGQLGLN-DENDRYVPNLLKSLRSQKIVYICCGEDHTAALTKEGGVFTFGAGGYGQLG 275
Query: 696 LGTISNKEMSPQHISSLIGVPIALIACGNNHTFV-LSKSGAVFGWGKNTHGXLG 854
+ S+ E++P+ + L+G + IACG HT + SG ++ +G +G LG
Sbjct: 276 HNSTSH-EINPRKVFELMGSIVTEIACGRQHTSAFVPSSGRIYSFGLGGNGQLG 328
Score = 100 bits (240), Expect = 6e-21
Identities = 64/189 (33%), Positives = 97/189 (51%), Gaps = 1/189 (0%)
Frame = +3
Query: 156 LQNYKKMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSG 335
L ++FCWG + +L + G+ P L K VAAG HS L+ SG
Sbjct: 152 LSKASEVFCWGQNKYGQLGL-GTDCKKQT-SPQLLKSLLGIPFMQVAAGGAHSFVLTLSG 209
Query: 336 HLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGS 515
++ G N GQLG E+D P L+++ + I I CG H+ A+ + G F++G+
Sbjct: 210 AIFGWGRNKFGQLGLNDENDRYV-PNLLKSLRSQKIVYICCGEDHTAALTKEGGVFTFGA 268
Query: 516 DSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALT-NSGDLYSWGANSYGQC 692
GQLG+N +H + P+ V L V ++ACG H+ A +SG +YS+G GQ
Sbjct: 269 GGYGQLGHNSTSH-EINPRKVFELMGSIVTEIACGRQHTSAFVPSSGRIYSFGLGGNGQL 327
Query: 693 GLGTISNKE 719
G G+ SN++
Sbjct: 328 GTGSTSNRK 336
>AL133551-3|CAI16032.1| 1049|Homo sapiens hect domain and RLD 4
protein.
Length = 1049
Score = 194 bits (472), Expect = 5e-49
Identities = 91/227 (40%), Positives = 139/227 (61%)
Frame = +3
Query: 174 MFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCG 353
M CWGNA+ +L + G ++V++P S + + ++ V G H++++ + G +Y+CG
Sbjct: 1 MLCWGNASFGQLGLGGID-EEIVLEPRKSDFFINKRVRDVGCGLRHTVFVLDDGTVYTCG 59
Query: 354 NNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQL 533
ND+GQLG + K P V I ++CG H+LA+++ GQ ++WG DS GQL
Sbjct: 60 CNDLGQLGHEKSR---KKPEQVVALDAQNIVAVSCGEAHTLALNDKGQVYAWGLDSDGQL 116
Query: 534 GNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTISN 713
G P+ +K L+ ++QVACG YHS+AL+ + +++ WG N YGQ GLGT
Sbjct: 117 GLVGSEECIRVPRNIKSLSDIQIVQVACGYYHSLALSKASEVFCWGQNKYGQLGLGTDCK 176
Query: 714 KEMSPQHISSLIGVPIALIACGNNHTFVLSKSGAVFGWGKNTHGXLG 854
K+ SPQ + SL+G+P +A G H+FVL+ SGA+FGWG+N G LG
Sbjct: 177 KQTSPQLLKSLLGIPFMQVAAGGAHSFVLTLSGAIFGWGRNKFGQLG 223
Score = 139 bits (336), Expect = 1e-32
Identities = 72/195 (36%), Positives = 103/195 (52%)
Frame = +3
Query: 270 ESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTIST 449
++ +I AV+ GE H+L L++ G +Y+ G + GQLG + + P +++ D I
Sbjct: 82 DAQNIVAVSCGEAHTLALNDKGQVYAWGLDSDGQLGLVGSEECIRVPRNIKSLSDIQIVQ 141
Query: 450 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 629
+ACG HSLA+ + + F WG + GQLG Q P+ +K L +QVA G H
Sbjct: 142 VACGYYHSLALSKASEVFCWGQNKYGQLGLGTDCKKQTSPQLLKSLLGIPFMQVAAGGAH 201
Query: 630 SVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFVLSKS 809
S LT SG ++ WG N +GQ GL N P + SL I I CG +HT L+K
Sbjct: 202 SFVLTLSGAIFGWGRNKFGQLGLND-ENDRYVPNLLKSLRSQKIVYICCGEDHTAALTKE 260
Query: 810 GAVFGWGKNTHGXLG 854
G VF +G +G LG
Sbjct: 261 GGVFTFGAGGYGQLG 275
Score = 128 bits (308), Expect = 3e-29
Identities = 72/234 (30%), Positives = 120/234 (51%), Gaps = 1/234 (0%)
Frame = +3
Query: 156 LQNYKKMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSG 335
L + +++ WG + +L + GS+ + + P K I VA G +HSL LS +
Sbjct: 99 LNDKGQVYAWGLDSDGQLGLVGSE--ECIRVPRNIKSLSDIQIVQVACGYYHSLALSKAS 156
Query: 336 HLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGS 515
++ G N GQLG T+ +P L+++ +A G HS + G F WG
Sbjct: 157 EVFCWGQNKYGQLGLGTDCKKQTSPQLLKSLLGIPFMQVAAGGAHSFVLTLSGAIFGWGR 216
Query: 516 DSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCG 695
+ GQLG N + + P +K L ++ ++ + CG H+ ALT G ++++GA YGQ G
Sbjct: 217 NKFGQLGLN-DENDRYVPNLLKSLRSQKIVYICCGEDHTAALTKEGGVFTFGAGGYGQLG 275
Query: 696 LGTISNKEMSPQHISSLIGVPIALIACGNNHTFV-LSKSGAVFGWGKNTHGXLG 854
+ S+ E++P+ + L+G + IACG HT + SG ++ +G +G LG
Sbjct: 276 HNSTSH-EINPRKVFELMGSIVTEIACGRQHTSAFVPSSGRIYSFGLGGNGQLG 328
Score = 100 bits (240), Expect = 6e-21
Identities = 64/189 (33%), Positives = 97/189 (51%), Gaps = 1/189 (0%)
Frame = +3
Query: 156 LQNYKKMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSG 335
L ++FCWG + +L + G+ P L K VAAG HS L+ SG
Sbjct: 152 LSKASEVFCWGQNKYGQLGL-GTDCKKQT-SPQLLKSLLGIPFMQVAAGGAHSFVLTLSG 209
Query: 336 HLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGS 515
++ G N GQLG E+D P L+++ + I I CG H+ A+ + G F++G+
Sbjct: 210 AIFGWGRNKFGQLGLNDENDRYV-PNLLKSLRSQKIVYICCGEDHTAALTKEGGVFTFGA 268
Query: 516 DSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALT-NSGDLYSWGANSYGQC 692
GQLG+N +H + P+ V L V ++ACG H+ A +SG +YS+G GQ
Sbjct: 269 GGYGQLGHNSTSH-EINPRKVFELMGSIVTEIACGRQHTSAFVPSSGRIYSFGLGGNGQL 327
Query: 693 GLGTISNKE 719
G G+ SN++
Sbjct: 328 GTGSTSNRK 336
>D25215-1|BAA04945.2| 1054|Homo sapiens KIAA0032 protein.
Length = 1054
Score = 180 bits (437), Expect = 8e-45
Identities = 90/229 (39%), Positives = 130/229 (56%)
Frame = +3
Query: 168 KKMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYS 347
+ M CWG + + I + + +V +P + + ++ VA G HS++L G +Y+
Sbjct: 3 RTMLCWGYWSLGQPGIS-TNLQGIVAEPQVCGFISDRSVKEVACGGNHSVFLLEDGEVYT 61
Query: 348 CGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMG 527
CG N GQLG + E G P + D I +ACG HSLA+ + GQ FSWG+ S G
Sbjct: 62 CGLNTKGQLGHERE---GNKPEQIGALADQHIIHVACGESHSLALSDRGQLFSWGAGSDG 118
Query: 528 QLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTI 707
QLG + P+ ++ L + ++QV+CG +H +AL G ++WG NS+GQ GLG
Sbjct: 119 QLGLMTTEDSVAVPRLIQKLNQQTILQVSCGNWHCLALAADGQFFTWGKNSHGQLGLGKE 178
Query: 708 SNKEMSPQHISSLIGVPIALIACGNNHTFVLSKSGAVFGWGKNTHGXLG 854
+ SPQ + SL G+P+A +A G H+F LS SGAVFGWG N G LG
Sbjct: 179 FPSQASPQRVRSLEGIPLAQVAAGGAHSFALSLSGAVFGWGMNNAGQLG 227
Score = 148 bits (358), Expect = 3e-35
Identities = 82/192 (42%), Positives = 108/192 (56%)
Frame = +3
Query: 279 HIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIAC 458
HI VA GE HSL LS+ G L+S G GQLG T D+ P L++ TI ++C
Sbjct: 89 HIIHVACGESHSLALSDRGQLFSWGAGSDGQLGLMTTEDSVAVPRLIQKLNQQTILQVSC 148
Query: 459 GLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVA 638
G H LA+ GQ F+WG +S GQLG +Q P+ V+ L + QVA G HS A
Sbjct: 149 GNWHCLALAADGQFFTWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAAGGAHSFA 208
Query: 639 LTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFVLSKSGAV 818
L+ SG ++ WG N+ GQ GL ++E SP H+ L + I+CG HT VL+KSG V
Sbjct: 209 LSLSGAVFGWGMNNAGQLGLSDEKDRE-SPCHVKLLRTQKVVYISCGEEHTAVLTKSGGV 267
Query: 819 FGWGKNTHGXLG 854
F +G + G LG
Sbjct: 268 FTFGAGSCGQLG 279
Score = 130 bits (315), Expect = 5e-30
Identities = 74/234 (31%), Positives = 122/234 (52%), Gaps = 1/234 (0%)
Frame = +3
Query: 156 LQNYKKMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSG 335
L + ++F WG + +L + ++ D V P L + I V+ G +H L L+ G
Sbjct: 103 LSDRGQLFSWGAGSDGQLGLMTTE--DSVAVPRLIQKLNQQTILQVSCGNWHCLALAADG 160
Query: 336 HLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGS 515
++ G N GQLG E + +P V + + ++ +A G HS A+ G F WG
Sbjct: 161 QFFTWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAAGGAHSFALSLSGAVFGWGM 220
Query: 516 DSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCG 695
++ GQLG + ++ P VK L T+ V+ ++CG H+ LT SG ++++GA S GQ G
Sbjct: 221 NNAGQLGLS-DEKDRESPCHVKLLRTQKVVYISCGEEHTAVLTKSGGVFTFGAGSCGQLG 279
Query: 696 LGTISNKEMSPQHISSLIGVPIALIACGNNHTFV-LSKSGAVFGWGKNTHGXLG 854
++ N E++P+ + L+G + IACG HT + SG ++ +G G LG
Sbjct: 280 HDSM-NDEVNPRRVLELMGSEVTQIACGRQHTLAFVPSSGLIYAFGCGARGQLG 332
Score = 95.5 bits (227), Expect = 2e-19
Identities = 59/182 (32%), Positives = 96/182 (52%), Gaps = 1/182 (0%)
Frame = +3
Query: 171 KMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSC 350
+ F WG +H +L + G + P + E + VAAG HS LS SG ++
Sbjct: 161 QFFTWGKNSHGQLGL-GKEFPSQA-SPQRVRSLEGIPLAQVAAGGAHSFALSLSGAVFGW 218
Query: 351 GNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQ 530
G N+ GQLG E D ++P V+ + + I+CG +H+ + + G F++G+ S GQ
Sbjct: 219 GMNNAGQLGLSDEKDR-ESPCHVKLLRTQKVVYISCGEEHTAVLTKSGGVFTFGAGSCGQ 277
Query: 531 LGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVA-LTNSGDLYSWGANSYGQCGLGTI 707
LG++ + + P+ V L V Q+ACG H++A + +SG +Y++G + GQ G G
Sbjct: 278 LGHD-SMNDEVNPRRVLELMGSEVTQIACGRQHTLAFVPSSGLIYAFGCGARGQLGTGHT 336
Query: 708 SN 713
N
Sbjct: 337 CN 338
>BC038960-1|AAH38960.1| 368|Homo sapiens HERC3 protein protein.
Length = 368
Score = 179 bits (436), Expect = 1e-44
Identities = 90/227 (39%), Positives = 129/227 (56%)
Frame = +3
Query: 174 MFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCG 353
M CWG + + I + + +V +P + + ++ VA G HS++L G +Y+CG
Sbjct: 1 MLCWGYWSLGQPGIS-TNLQGIVAEPQVCGFISDRSVKEVACGGNHSVFLLEDGEVYTCG 59
Query: 354 NNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQL 533
N GQLG + E G P + D I +ACG HSLA+ + GQ FSWG+ S GQL
Sbjct: 60 LNTKGQLGHERE---GNKPEQIGALADQHIIHVACGESHSLALSDRGQLFSWGAGSDGQL 116
Query: 534 GNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTISN 713
G + P+ ++ L + ++QV+CG +H +AL G ++WG NS+GQ GLG
Sbjct: 117 GLMTTEDSVAVPRLIQKLNQQTILQVSCGNWHCLALAADGQFFTWGKNSHGQLGLGKEFP 176
Query: 714 KEMSPQHISSLIGVPIALIACGNNHTFVLSKSGAVFGWGKNTHGXLG 854
+ SPQ + SL G+P+A +A G H+F LS SGAVFGWG N G LG
Sbjct: 177 SQASPQRVRSLEGIPLAQVAAGGAHSFALSLSGAVFGWGMNNAGQLG 223
Score = 148 bits (358), Expect = 3e-35
Identities = 82/192 (42%), Positives = 108/192 (56%)
Frame = +3
Query: 279 HIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIAC 458
HI VA GE HSL LS+ G L+S G GQLG T D+ P L++ TI ++C
Sbjct: 85 HIIHVACGESHSLALSDRGQLFSWGAGSDGQLGLMTTEDSVAVPRLIQKLNQQTILQVSC 144
Query: 459 GLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVA 638
G H LA+ GQ F+WG +S GQLG +Q P+ V+ L + QVA G HS A
Sbjct: 145 GNWHCLALAADGQFFTWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAAGGAHSFA 204
Query: 639 LTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFVLSKSGAV 818
L+ SG ++ WG N+ GQ GL ++E SP H+ L + I+CG HT VL+KSG V
Sbjct: 205 LSLSGAVFGWGMNNAGQLGLSDEKDRE-SPCHVKLLRTQKVVYISCGEEHTAVLTKSGGV 263
Query: 819 FGWGKNTHGXLG 854
F +G + G LG
Sbjct: 264 FTFGAGSCGQLG 275
Score = 130 bits (315), Expect = 5e-30
Identities = 74/234 (31%), Positives = 122/234 (52%), Gaps = 1/234 (0%)
Frame = +3
Query: 156 LQNYKKMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSG 335
L + ++F WG + +L + ++ D V P L + I V+ G +H L L+ G
Sbjct: 99 LSDRGQLFSWGAGSDGQLGLMTTE--DSVAVPRLIQKLNQQTILQVSCGNWHCLALAADG 156
Query: 336 HLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGS 515
++ G N GQLG E + +P V + + ++ +A G HS A+ G F WG
Sbjct: 157 QFFTWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAAGGAHSFALSLSGAVFGWGM 216
Query: 516 DSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCG 695
++ GQLG + ++ P VK L T+ V+ ++CG H+ LT SG ++++GA S GQ G
Sbjct: 217 NNAGQLGLS-DEKDRESPCHVKLLRTQKVVYISCGEEHTAVLTKSGGVFTFGAGSCGQLG 275
Query: 696 LGTISNKEMSPQHISSLIGVPIALIACGNNHTFV-LSKSGAVFGWGKNTHGXLG 854
++ N E++P+ + L+G + IACG HT + SG ++ +G G LG
Sbjct: 276 HDSM-NDEVNPRRVLELMGSEVTQIACGRQHTLAFVPSSGLIYAFGCGARGQLG 328
Score = 95.5 bits (227), Expect = 2e-19
Identities = 59/182 (32%), Positives = 96/182 (52%), Gaps = 1/182 (0%)
Frame = +3
Query: 171 KMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSC 350
+ F WG +H +L + G + P + E + VAAG HS LS SG ++
Sbjct: 157 QFFTWGKNSHGQLGL-GKEFPSQA-SPQRVRSLEGIPLAQVAAGGAHSFALSLSGAVFGW 214
Query: 351 GNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQ 530
G N+ GQLG E D ++P V+ + + I+CG +H+ + + G F++G+ S GQ
Sbjct: 215 GMNNAGQLGLSDEKDR-ESPCHVKLLRTQKVVYISCGEEHTAVLTKSGGVFTFGAGSCGQ 273
Query: 531 LGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVA-LTNSGDLYSWGANSYGQCGLGTI 707
LG++ + + P+ V L V Q+ACG H++A + +SG +Y++G + GQ G G
Sbjct: 274 LGHD-SMNDEVNPRRVLELMGSEVTQIACGRQHTLAFVPSSGLIYAFGCGARGQLGTGHT 332
Query: 708 SN 713
N
Sbjct: 333 CN 334
>AC098582-1|AAY41038.1| 382|Homo sapiens unknown protein.
Length = 382
Score = 179 bits (436), Expect = 1e-44
Identities = 90/227 (39%), Positives = 129/227 (56%)
Frame = +3
Query: 174 MFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCG 353
M CWG + + I + + +V +P + + ++ VA G HS++L G +Y+CG
Sbjct: 1 MLCWGYWSLGQPGIS-TNLQGIVAEPQVCGFISDRSVKEVACGGNHSVFLLEDGEVYTCG 59
Query: 354 NNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQL 533
N GQLG + E G P + D I +ACG HSLA+ + GQ FSWG+ S GQL
Sbjct: 60 LNTKGQLGHERE---GNKPEQIGALADQHIIHVACGESHSLALSDRGQLFSWGAGSDGQL 116
Query: 534 GNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTISN 713
G + P+ ++ L + ++QV+CG +H +AL G ++WG NS+GQ GLG
Sbjct: 117 GLMTTEDSVAVPRLIQKLNQQTILQVSCGNWHCLALAADGQFFTWGKNSHGQLGLGKEFP 176
Query: 714 KEMSPQHISSLIGVPIALIACGNNHTFVLSKSGAVFGWGKNTHGXLG 854
+ SPQ + SL G+P+A +A G H+F LS SGAVFGWG N G LG
Sbjct: 177 SQASPQRVRSLEGIPLAQVAAGGAHSFALSLSGAVFGWGMNNAGQLG 223
Score = 148 bits (358), Expect = 3e-35
Identities = 82/192 (42%), Positives = 108/192 (56%)
Frame = +3
Query: 279 HIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIAC 458
HI VA GE HSL LS+ G L+S G GQLG T D+ P L++ TI ++C
Sbjct: 85 HIIHVACGESHSLALSDRGQLFSWGAGSDGQLGLMTTEDSVAVPRLIQKLNQQTILQVSC 144
Query: 459 GLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVA 638
G H LA+ GQ F+WG +S GQLG +Q P+ V+ L + QVA G HS A
Sbjct: 145 GNWHCLALAADGQFFTWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAAGGAHSFA 204
Query: 639 LTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFVLSKSGAV 818
L+ SG ++ WG N+ GQ GL ++E SP H+ L + I+CG HT VL+KSG V
Sbjct: 205 LSLSGAVFGWGMNNAGQLGLSDEKDRE-SPCHVKLLRTQKVVYISCGEEHTAVLTKSGGV 263
Query: 819 FGWGKNTHGXLG 854
F +G + G LG
Sbjct: 264 FTFGAGSCGQLG 275
Score = 130 bits (315), Expect = 5e-30
Identities = 74/234 (31%), Positives = 122/234 (52%), Gaps = 1/234 (0%)
Frame = +3
Query: 156 LQNYKKMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSG 335
L + ++F WG + +L + ++ D V P L + I V+ G +H L L+ G
Sbjct: 99 LSDRGQLFSWGAGSDGQLGLMTTE--DSVAVPRLIQKLNQQTILQVSCGNWHCLALAADG 156
Query: 336 HLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGS 515
++ G N GQLG E + +P V + + ++ +A G HS A+ G F WG
Sbjct: 157 QFFTWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAAGGAHSFALSLSGAVFGWGM 216
Query: 516 DSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCG 695
++ GQLG + ++ P VK L T+ V+ ++CG H+ LT SG ++++GA S GQ G
Sbjct: 217 NNAGQLGLS-DEKDRESPCHVKLLRTQKVVYISCGEEHTAVLTKSGGVFTFGAGSCGQLG 275
Query: 696 LGTISNKEMSPQHISSLIGVPIALIACGNNHTFV-LSKSGAVFGWGKNTHGXLG 854
++ N E++P+ + L+G + IACG HT + SG ++ +G G LG
Sbjct: 276 HDSM-NDEVNPRRVLELMGSEVTQIACGRQHTLAFVPSSGLIYAFGCGARGQLG 328
Score = 95.5 bits (227), Expect = 2e-19
Identities = 59/182 (32%), Positives = 96/182 (52%), Gaps = 1/182 (0%)
Frame = +3
Query: 171 KMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSC 350
+ F WG +H +L + G + P + E + VAAG HS LS SG ++
Sbjct: 157 QFFTWGKNSHGQLGL-GKEFPSQA-SPQRVRSLEGIPLAQVAAGGAHSFALSLSGAVFGW 214
Query: 351 GNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQ 530
G N+ GQLG E D ++P V+ + + I+CG +H+ + + G F++G+ S GQ
Sbjct: 215 GMNNAGQLGLSDEKDR-ESPCHVKLLRTQKVVYISCGEEHTAVLTKSGGVFTFGAGSCGQ 273
Query: 531 LGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVA-LTNSGDLYSWGANSYGQCGLGTI 707
LG++ + + P+ V L V Q+ACG H++A + +SG +Y++G + GQ G G
Sbjct: 274 LGHD-SMNDEVNPRRVLELMGSEVTQIACGRQHTLAFVPSSGLIYAFGCGARGQLGTGHT 332
Query: 708 SN 713
N
Sbjct: 333 CN 334
>BC042047-1|AAH42047.2| 1022|Homo sapiens hect domain and RLD 6
protein.
Length = 1022
Score = 162 bits (394), Expect = 1e-39
Identities = 78/186 (41%), Positives = 111/186 (59%)
Frame = +3
Query: 294 AAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHS 473
A+GE HSL L + + SCG+N GQLGR+ + G+ P ++ + + ++CG +HS
Sbjct: 29 ASGERHSLLLLTNHRVLSCGDNSRGQLGRRG-AQRGELPEPIQALETLIVDLVSCGKEHS 87
Query: 474 LAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSG 653
LA+ G+ F+WG+ S GQLG PK + L +IQV+CG YHS+AL+
Sbjct: 88 LAVCHKGRVFAWGAGSEGQLGIGEFKEISFTPKKIMTLNDIKIIQVSCGHYHSLALSKDS 147
Query: 654 DLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFVLSKSGAVFGWGK 833
++SWG NS+GQ GLG + SPQ + SL G+P+A +A G H+F LS G FGWG
Sbjct: 148 QVFSWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAAGGAHSFALSLCGTSFGWGS 207
Query: 834 NTHGXL 851
N+ G L
Sbjct: 208 NSAGQL 213
Score = 126 bits (305), Expect = 8e-29
Identities = 78/235 (33%), Positives = 121/235 (51%), Gaps = 2/235 (0%)
Frame = +3
Query: 156 LQNYKKMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSG 335
L N++ + C G+ + +L G+Q +L P + E+ + V+ G+ HSL + + G
Sbjct: 39 LTNHRVLSC-GDNSRGQLGRRGAQRGEL---PEPIQALETLIVDLVSCGKEHSLAVCHKG 94
Query: 336 HLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGS 515
+++ G GQLG + P + T D I ++CG HSLA+ + Q FSWG
Sbjct: 95 RVFAWGAGSEGQLGIGEFKEISFTPKKIMTLNDIKIIQVSCGHYHSLALSKDSQVFSWGK 154
Query: 516 DSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCG 695
+S GQLG +Q P+ V+ L + QVA G HS AL+ G + WG+NS GQ
Sbjct: 155 NSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAAGGAHSFALSLCGTSFGWGSNSAGQLA 214
Query: 696 LG--TISNKEMSPQHISSLIGVPIALIACGNNHTFVLSKSGAVFGWGKNTHGXLG 854
L + + P + +L + + I+CG+ HT VL++ G VF +G N G LG
Sbjct: 215 LSGRNVPVQSNKPLSVGALKNLGVVYISCGDAHTAVLTQDGKVFTFGDNRSGQLG 269
Score = 109 bits (262), Expect = 1e-23
Identities = 68/224 (30%), Positives = 108/224 (48%), Gaps = 4/224 (1%)
Frame = +3
Query: 171 KMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSC 350
++F WG + +L I + ++ P I V+ G +HSL LS ++S
Sbjct: 95 RVFAWGAGSEGQLGI--GEFKEISFTPKKIMTLNDIKIIQVSCGHYHSLALSKDSQVFSW 152
Query: 351 GNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQ 530
G N GQLG E + +P V + + ++ +A G HS A+ G F WGS+S GQ
Sbjct: 153 GKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAAGGAHSFALSLCGTSFGWGSNSAGQ 212
Query: 531 L---GNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLG 701
L G N+ + +KP V L V+ ++CG H+ LT G ++++G N GQ G
Sbjct: 213 LALSGRNVPVQS-NKPLSVGALKNLGVVYISCGDAHTAVLTQDGKVFTFGDNRSGQLGYS 271
Query: 702 TISNKEMSPQHISSLIGVPIALIACGNNHTFV-LSKSGAVFGWG 830
K PQ + + G+ ++ I CG+ HT + +G V +G
Sbjct: 272 PTPEKR-GPQLVERIDGL-VSQIDCGSYHTLAYVHTTGQVVSFG 313
>AY653203-1|AAV66897.1| 322|Homo sapiens truncated HERC6 protein.
Length = 322
Score = 162 bits (394), Expect = 1e-39
Identities = 78/186 (41%), Positives = 111/186 (59%)
Frame = +3
Query: 294 AAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHS 473
A+GE HSL L + + SCG+N GQLGR+ + G+ P ++ + + ++CG +HS
Sbjct: 29 ASGERHSLLLLTNHRVLSCGDNSRGQLGRRG-AQRGELPEPIQALETLIVDLVSCGKEHS 87
Query: 474 LAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSG 653
LA+ G+ F+WG+ S GQLG PK + L +IQV+CG YHS+AL+
Sbjct: 88 LAVCHKGRVFAWGAGSEGQLGIGEFKEISFTPKKIMTLNDIKIIQVSCGHYHSLALSKDS 147
Query: 654 DLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFVLSKSGAVFGWGK 833
++SWG NS+GQ GLG + SPQ + SL G+P+A +A G H+F LS G FGWG
Sbjct: 148 QVFSWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAAGGAHSFALSLCGTSFGWGS 207
Query: 834 NTHGXL 851
N+ G L
Sbjct: 208 NSAGQL 213
Score = 126 bits (305), Expect = 8e-29
Identities = 78/235 (33%), Positives = 121/235 (51%), Gaps = 2/235 (0%)
Frame = +3
Query: 156 LQNYKKMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSG 335
L N++ + C G+ + +L G+Q +L P + E+ + V+ G+ HSL + + G
Sbjct: 39 LTNHRVLSC-GDNSRGQLGRRGAQRGEL---PEPIQALETLIVDLVSCGKEHSLAVCHKG 94
Query: 336 HLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGS 515
+++ G GQLG + P + T D I ++CG HSLA+ + Q FSWG
Sbjct: 95 RVFAWGAGSEGQLGIGEFKEISFTPKKIMTLNDIKIIQVSCGHYHSLALSKDSQVFSWGK 154
Query: 516 DSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCG 695
+S GQLG +Q P+ V+ L + QVA G HS AL+ G + WG+NS GQ
Sbjct: 155 NSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAAGGAHSFALSLCGTSFGWGSNSAGQLA 214
Query: 696 LG--TISNKEMSPQHISSLIGVPIALIACGNNHTFVLSKSGAVFGWGKNTHGXLG 854
L + + P + +L + + I+CG+ HT VL++ G VF +G N G LG
Sbjct: 215 LSGRNVPVQSNKPLSVGALKNLGVVYISCGDAHTAVLTQDGKVFTFGDNRSGQLG 269
Score = 103 bits (246), Expect = 1e-21
Identities = 63/206 (30%), Positives = 99/206 (48%), Gaps = 3/206 (1%)
Frame = +3
Query: 171 KMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSC 350
++F WG + +L I + ++ P I V+ G +HSL LS ++S
Sbjct: 95 RVFAWGAGSEGQLGI--GEFKEISFTPKKIMTLNDIKIIQVSCGHYHSLALSKDSQVFSW 152
Query: 351 GNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQ 530
G N GQLG E + +P V + + ++ +A G HS A+ G F WGS+S GQ
Sbjct: 153 GKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAAGGAHSFALSLCGTSFGWGSNSAGQ 212
Query: 531 L---GNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLG 701
L G N+ + +KP V L V+ ++CG H+ LT G ++++G N GQ G
Sbjct: 213 LALSGRNVPVQS-NKPLSVGALKNLGVVYISCGDAHTAVLTQDGKVFTFGDNRSGQLGYS 271
Query: 702 TISNKEMSPQHISSLIGVPIALIACG 779
K PQ + + G+ ++ I CG
Sbjct: 272 PTPEKR-GPQLVERIDGL-VSQIDCG 295
>AY653202-1|AAV66896.1| 364|Homo sapiens truncated HERC6 protein.
Length = 364
Score = 162 bits (394), Expect = 1e-39
Identities = 78/186 (41%), Positives = 111/186 (59%)
Frame = +3
Query: 294 AAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHS 473
A+GE HSL L + + SCG+N GQLGR+ + G+ P ++ + + ++CG +HS
Sbjct: 29 ASGERHSLLLLTNHRVLSCGDNSRGQLGRRG-AQRGELPEPIQALETLIVDLVSCGKEHS 87
Query: 474 LAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSG 653
LA+ G+ F+WG+ S GQLG PK + L +IQV+CG YHS+AL+
Sbjct: 88 LAVCHKGRVFAWGAGSEGQLGIGEFKEISFTPKKIMTLNDIKIIQVSCGHYHSLALSKDS 147
Query: 654 DLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFVLSKSGAVFGWGK 833
++SWG NS+GQ GLG + SPQ + SL G+P+A +A G H+F LS G FGWG
Sbjct: 148 QVFSWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAAGGAHSFALSLCGTSFGWGS 207
Query: 834 NTHGXL 851
N+ G L
Sbjct: 208 NSAGQL 213
Score = 126 bits (305), Expect = 8e-29
Identities = 78/235 (33%), Positives = 121/235 (51%), Gaps = 2/235 (0%)
Frame = +3
Query: 156 LQNYKKMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSG 335
L N++ + C G+ + +L G+Q +L P + E+ + V+ G+ HSL + + G
Sbjct: 39 LTNHRVLSC-GDNSRGQLGRRGAQRGEL---PEPIQALETLIVDLVSCGKEHSLAVCHKG 94
Query: 336 HLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGS 515
+++ G GQLG + P + T D I ++CG HSLA+ + Q FSWG
Sbjct: 95 RVFAWGAGSEGQLGIGEFKEISFTPKKIMTLNDIKIIQVSCGHYHSLALSKDSQVFSWGK 154
Query: 516 DSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCG 695
+S GQLG +Q P+ V+ L + QVA G HS AL+ G + WG+NS GQ
Sbjct: 155 NSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAAGGAHSFALSLCGTSFGWGSNSAGQLA 214
Query: 696 LG--TISNKEMSPQHISSLIGVPIALIACGNNHTFVLSKSGAVFGWGKNTHGXLG 854
L + + P + +L + + I+CG+ HT VL++ G VF +G N G LG
Sbjct: 215 LSGRNVPVQSNKPLSVGALKNLGVVYISCGDAHTAVLTQDGKVFTFGDNRSGQLG 269
Score = 109 bits (262), Expect = 1e-23
Identities = 68/224 (30%), Positives = 108/224 (48%), Gaps = 4/224 (1%)
Frame = +3
Query: 171 KMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSC 350
++F WG + +L I + ++ P I V+ G +HSL LS ++S
Sbjct: 95 RVFAWGAGSEGQLGI--GEFKEISFTPKKIMTLNDIKIIQVSCGHYHSLALSKDSQVFSW 152
Query: 351 GNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQ 530
G N GQLG E + +P V + + ++ +A G HS A+ G F WGS+S GQ
Sbjct: 153 GKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAAGGAHSFALSLCGTSFGWGSNSAGQ 212
Query: 531 L---GNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLG 701
L G N+ + +KP V L V+ ++CG H+ LT G ++++G N GQ G
Sbjct: 213 LALSGRNVPVQS-NKPLSVGALKNLGVVYISCGDAHTAVLTQDGKVFTFGDNRSGQLGYS 271
Query: 702 TISNKEMSPQHISSLIGVPIALIACGNNHTFV-LSKSGAVFGWG 830
K PQ + + G+ ++ I CG+ HT + +G V +G
Sbjct: 272 PTPEKR-GPQLVERIDGL-VSQIDCGSYHTLAYVHTTGQVVSFG 313
>AY653201-1|AAV66895.1| 986|Homo sapiens HERC6 splice variant
protein.
Length = 986
Score = 162 bits (394), Expect = 1e-39
Identities = 78/186 (41%), Positives = 111/186 (59%)
Frame = +3
Query: 294 AAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHS 473
A+GE HSL L + + SCG+N GQLGR+ + G+ P ++ + + ++CG +HS
Sbjct: 29 ASGERHSLLLLTNHRVLSCGDNSRGQLGRRG-AQRGELPEPIQALETLIVDLVSCGKEHS 87
Query: 474 LAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSG 653
LA+ G+ F+WG+ S GQLG PK + L +IQV+CG YHS+AL+
Sbjct: 88 LAVCHKGRVFAWGAGSEGQLGIGEFKEISFTPKKIMTLNDIKIIQVSCGHYHSLALSKDS 147
Query: 654 DLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFVLSKSGAVFGWGK 833
++SWG NS+GQ GLG + SPQ + SL G+P+A +A G H+F LS G FGWG
Sbjct: 148 QVFSWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAAGGAHSFALSLCGTSFGWGS 207
Query: 834 NTHGXL 851
N+ G L
Sbjct: 208 NSAGQL 213
Score = 126 bits (305), Expect = 8e-29
Identities = 78/235 (33%), Positives = 121/235 (51%), Gaps = 2/235 (0%)
Frame = +3
Query: 156 LQNYKKMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSG 335
L N++ + C G+ + +L G+Q +L P + E+ + V+ G+ HSL + + G
Sbjct: 39 LTNHRVLSC-GDNSRGQLGRRGAQRGEL---PEPIQALETLIVDLVSCGKEHSLAVCHKG 94
Query: 336 HLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGS 515
+++ G GQLG + P + T D I ++CG HSLA+ + Q FSWG
Sbjct: 95 RVFAWGAGSEGQLGIGEFKEISFTPKKIMTLNDIKIIQVSCGHYHSLALSKDSQVFSWGK 154
Query: 516 DSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCG 695
+S GQLG +Q P+ V+ L + QVA G HS AL+ G + WG+NS GQ
Sbjct: 155 NSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAAGGAHSFALSLCGTSFGWGSNSAGQLA 214
Query: 696 LG--TISNKEMSPQHISSLIGVPIALIACGNNHTFVLSKSGAVFGWGKNTHGXLG 854
L + + P + +L + + I+CG+ HT VL++ G VF +G N G LG
Sbjct: 215 LSGRNVPVQSNKPLSVGALKNLGVVYISCGDAHTAVLTQDGKVFTFGDNRSGQLG 269
Score = 109 bits (262), Expect = 1e-23
Identities = 68/224 (30%), Positives = 108/224 (48%), Gaps = 4/224 (1%)
Frame = +3
Query: 171 KMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSC 350
++F WG + +L I + ++ P I V+ G +HSL LS ++S
Sbjct: 95 RVFAWGAGSEGQLGI--GEFKEISFTPKKIMTLNDIKIIQVSCGHYHSLALSKDSQVFSW 152
Query: 351 GNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQ 530
G N GQLG E + +P V + + ++ +A G HS A+ G F WGS+S GQ
Sbjct: 153 GKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAAGGAHSFALSLCGTSFGWGSNSAGQ 212
Query: 531 L---GNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLG 701
L G N+ + +KP V L V+ ++CG H+ LT G ++++G N GQ G
Sbjct: 213 LALSGRNVPVQS-NKPLSVGALKNLGVVYISCGDAHTAVLTQDGKVFTFGDNRSGQLGYS 271
Query: 702 TISNKEMSPQHISSLIGVPIALIACGNNHTFV-LSKSGAVFGWG 830
K PQ + + G+ ++ I CG+ HT + +G V +G
Sbjct: 272 PTPEKR-GPQLVERIDGL-VSQIDCGSYHTLAYVHTTGQVVSFG 313
>AF336798-1|AAQ14893.1| 1022|Homo sapiens HERC6 protein.
Length = 1022
Score = 162 bits (394), Expect = 1e-39
Identities = 78/186 (41%), Positives = 111/186 (59%)
Frame = +3
Query: 294 AAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHS 473
A+GE HSL L + + SCG+N GQLGR+ + G+ P ++ + + ++CG +HS
Sbjct: 29 ASGERHSLLLLTNHRVLSCGDNSRGQLGRRG-AQRGELPEPIQALETLIVDLVSCGKEHS 87
Query: 474 LAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSG 653
LA+ G+ F+WG+ S GQLG PK + L +IQV+CG YHS+AL+
Sbjct: 88 LAVCHKGRVFAWGAGSEGQLGIGEFKEISFTPKKIMTLNDIKIIQVSCGHYHSLALSKDS 147
Query: 654 DLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFVLSKSGAVFGWGK 833
++SWG NS+GQ GLG + SPQ + SL G+P+A +A G H+F LS G FGWG
Sbjct: 148 QVFSWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAAGGAHSFALSLCGTSFGWGS 207
Query: 834 NTHGXL 851
N+ G L
Sbjct: 208 NSAGQL 213
Score = 126 bits (305), Expect = 8e-29
Identities = 78/235 (33%), Positives = 121/235 (51%), Gaps = 2/235 (0%)
Frame = +3
Query: 156 LQNYKKMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSG 335
L N++ + C G+ + +L G+Q +L P + E+ + V+ G+ HSL + + G
Sbjct: 39 LTNHRVLSC-GDNSRGQLGRRGAQRGEL---PEPIQALETLIVDLVSCGKEHSLAVCHKG 94
Query: 336 HLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGS 515
+++ G GQLG + P + T D I ++CG HSLA+ + Q FSWG
Sbjct: 95 RVFAWGAGSEGQLGIGEFKEISFTPKKIMTLNDIKIIQVSCGHYHSLALSKDSQVFSWGK 154
Query: 516 DSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCG 695
+S GQLG +Q P+ V+ L + QVA G HS AL+ G + WG+NS GQ
Sbjct: 155 NSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAAGGAHSFALSLCGTSFGWGSNSAGQLA 214
Query: 696 LG--TISNKEMSPQHISSLIGVPIALIACGNNHTFVLSKSGAVFGWGKNTHGXLG 854
L + + P + +L + + I+CG+ HT VL++ G VF +G N G LG
Sbjct: 215 LSGRNVPVQSNKPLSVGALKNLGVVYISCGDAHTAVLTQDGKVFTFGDNRSGQLG 269
Score = 109 bits (262), Expect = 1e-23
Identities = 68/224 (30%), Positives = 108/224 (48%), Gaps = 4/224 (1%)
Frame = +3
Query: 171 KMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSC 350
++F WG + +L I + ++ P I V+ G +HSL LS ++S
Sbjct: 95 RVFAWGAGSEGQLGI--GEFKEISFTPKKIMTLNDIKIIQVSCGHYHSLALSKDSQVFSW 152
Query: 351 GNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQ 530
G N GQLG E + +P V + + ++ +A G HS A+ G F WGS+S GQ
Sbjct: 153 GKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAAGGAHSFALSLCGTSFGWGSNSAGQ 212
Query: 531 L---GNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLG 701
L G N+ + +KP V L V+ ++CG H+ LT G ++++G N GQ G
Sbjct: 213 LALSGRNVPVQS-NKPLSVGALKNLGVVYISCGDAHTAVLTQDGKVFTFGDNRSGQLGYS 271
Query: 702 TISNKEMSPQHISSLIGVPIALIACGNNHTFV-LSKSGAVFGWG 830
K PQ + + G+ ++ I CG+ HT + +G V +G
Sbjct: 272 PTPEKR-GPQLVERIDGL-VSQIDCGSYHTLAYVHTTGQVVSFG 313
>AB027289-1|BAA88519.1| 1024|Homo sapiens cyclin-E binding protein 1
protein.
Length = 1024
Score = 128 bits (310), Expect = 2e-29
Identities = 71/190 (37%), Positives = 103/190 (54%), Gaps = 2/190 (1%)
Frame = +3
Query: 291 VAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQH 470
+ G++HSL LS G L++ G N GQLG + + P +VE ++ I+ G H
Sbjct: 143 ITCGDYHSLALSKGGELFAWGQNLHGQLGVGRKFPSTTTPQIVEHLAGVPLAQISAGEAH 202
Query: 471 SLAIDEWGQPFSWGSDSMGQLGNNLG-AHAQDKPKFVKGLATKNVIQVACGAYHSVALTN 647
S+A+ G +SWG + GQLG LG ++D P ++GL + V VACG HS LT
Sbjct: 203 SMALSMSGNIYSWGKNECGQLG--LGHTESKDDPSLIEGLDNQKVEFVACGGSHSALLTQ 260
Query: 648 SGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFV-LSKSGAVFG 824
G L+++GA +GQ G + N E+ P ++ L+G + IACG HT +S G VF
Sbjct: 261 DGLLFTFGAGKHGQLGHNSTQN-ELRPCLVAELVGYRVTQIACGRWHTLAYVSDLGKVFS 319
Query: 825 WGKNTHGXLG 854
+G G LG
Sbjct: 320 FGSGKDGQLG 329
Score = 110 bits (264), Expect = 7e-24
Identities = 59/162 (36%), Positives = 89/162 (54%), Gaps = 2/162 (1%)
Frame = +3
Query: 375 GRQTESDNG--KNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLG 548
G+ E DN K+ ++ I I CG HSLA+ + G+ F+WG + GQLG
Sbjct: 116 GKPFEYDNYSMKHLRFESILQEKKIIQITCGDYHSLALSKGGELFAWGQNLHGQLGVGRK 175
Query: 549 AHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTISNKEMSP 728
+ P+ V+ LA + Q++ G HS+AL+ SG++YSWG N GQ GLG +K+ P
Sbjct: 176 FPSTTTPQIVEHLAGVPLAQISAGEAHSMALSMSGNIYSWGKNECGQLGLGHTESKD-DP 234
Query: 729 QHISSLIGVPIALIACGNNHTFVLSKSGAVFGWGKNTHGXLG 854
I L + +ACG +H+ +L++ G +F +G HG LG
Sbjct: 235 SLIEGLDNQKVEFVACGGSHSALLTQDGLLFTFGAGKHGQLG 276
Score = 108 bits (259), Expect = 3e-23
Identities = 55/155 (35%), Positives = 83/155 (53%)
Frame = +3
Query: 390 SDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKP 569
S + P ++ K+ I ++ G +H L + G+PF + + SM L
Sbjct: 82 SGGARTPKCIKLGKNMKIHSVDQGAEHMLILSSDGKPFEYDNYSMKHL------------ 129
Query: 570 KFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLI 749
+F L K +IQ+ CG YHS+AL+ G+L++WG N +GQ G+G +PQ + L
Sbjct: 130 RFESILQEKKIIQITCGDYHSLALSKGGELFAWGQNLHGQLGVGRKFPSTTTPQIVEHLA 189
Query: 750 GVPIALIACGNNHTFVLSKSGAVFGWGKNTHGXLG 854
GVP+A I+ G H+ LS SG ++ WGKN G LG
Sbjct: 190 GVPLAQISAGEAHSMALSMSGNIYSWGKNECGQLG 224
Score = 66.1 bits (154), Expect = 2e-10
Identities = 45/137 (32%), Positives = 69/137 (50%), Gaps = 1/137 (0%)
Frame = +3
Query: 174 MFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCG 353
++ WG +L + ++ D P+L + ++ ++ VA G HS L+ G L++ G
Sbjct: 212 IYSWGKNECGQLGLGHTESKD---DPSLIEGLDNQKVEFVACGGSHSALLTQDGLLFTFG 268
Query: 354 NNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLA-IDEWGQPFSWGSDSMGQ 530
GQLG + + N P LV ++ IACG H+LA + + G+ FS+GS GQ
Sbjct: 269 AGKHGQLGHNS-TQNELRPCLVAELVGYRVTQIACGRWHTLAYVSDLGKVFSFGSGKDGQ 327
Query: 531 LGNNLGAHAQDKPKFVK 581
LGN G Q P VK
Sbjct: 328 LGNG-GTRDQLMPLPVK 343
>U50078-1|AAD12586.1| 4861|Homo sapiens p532 protein.
Length = 4861
Score = 127 bits (307), Expect = 4e-29
Identities = 71/231 (30%), Positives = 124/231 (53%), Gaps = 4/231 (1%)
Frame = +3
Query: 174 MFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCG 353
++ WG H +L G + P+ S+ Q V G+ + + +G + +CG
Sbjct: 3999 VYLWGAGRHGQLAEAGRNVMVPAAAPSFSQ------AQQVICGQNCTFVIQANGTVLACG 4052
Query: 354 NNDVGQLGRQTESDNGKNPALVETFKDCTISTI--ACGLQ-HSLAIDEWGQPFSWGSDSM 524
G+LG Q SD+ ++ + ++ + +CG HS+A+ E G+ FSWG
Sbjct: 4053 EGSYGRLG-QGNSDDLHVLTVISALQGFVVTQLVTSCGSDGHSMALTESGEVFSWGDGDY 4111
Query: 525 GQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGT 704
G+LG+ + Q +P+ ++ L + V+Q++CG HS +T+ G L+++G YG+ GLG
Sbjct: 4112 GKLGHG-NSDRQRRPRQIEALQGEEVVQMSCGFKHSAVVTSDGKLFTFGNGDYGRLGLGN 4170
Query: 705 ISNKEMSPQHISSLIGVPIALIACGNNHTFVLSKSGA-VFGWGKNTHGXLG 854
SNK++ P+ +++L G I +ACG NHT +S G+ V+ +G +G LG
Sbjct: 4171 TSNKKL-PERVTALEGYQIGQVACGLNHTLAVSADGSMVWAFGDGDYGKLG 4220
Score = 115 bits (277), Expect = 2e-25
Identities = 73/229 (31%), Positives = 115/229 (50%), Gaps = 1/229 (0%)
Frame = +3
Query: 171 KMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSC 350
++F WG+ + +L G +D +P + + + + ++ G HS +++ G L++
Sbjct: 4102 EVFSWGDGDYGKL---GHGNSDRQRRPRQIEALQGEEVVQMSCGFKHSAVVTSDGKLFTF 4158
Query: 351 GNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQP-FSWGSDSMG 527
GN D G+LG S N K P V + I +ACGL H+LA+ G +++G G
Sbjct: 4159 GNGDYGRLGLGNTS-NKKLPERVTALEGYQIGQVACGLNHTLAVSADGSMVWAFGDGDYG 4217
Query: 528 QLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTI 707
+LG + A+ P+ + L + +VACG SVALT G +Y++G + G
Sbjct: 4218 KLGLG-NSTAKSSPQKIDVLCGIGIKKVACGTQFSVALTKDGHVYTFGQDRLIGLPEGRA 4276
Query: 708 SNKEMSPQHISSLIGVPIALIACGNNHTFVLSKSGAVFGWGKNTHGXLG 854
N PQ I L GV I +A G HT L+ +G V+ WG N+ G LG
Sbjct: 4277 RNHNR-PQQIPVLAGVIIEDVAVGAEHTLALASNGDVYAWGSNSEGQLG 4324
Score = 111 bits (268), Expect = 2e-24
Identities = 72/232 (31%), Positives = 122/232 (52%), Gaps = 4/232 (1%)
Frame = +3
Query: 171 KMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSC 350
+++ WG+ + H+L ++G+Q + +++P L+ SD Q + AG++ + +S G + +C
Sbjct: 373 EVYVWGSNSSHQL-VEGTQ--EKILQPKLAP-SFSD-AQTIEAGQYCTFVISTDGSVRAC 427
Query: 351 GNNDVGQLGRQTESDNGKNPALV-ETFKDC-TISTIACGLQHSLAIDEWGQPFSWGSDSM 524
G G+LG ++ L E + +S+ H+LA G+ FSWG
Sbjct: 428 GKGSYGRLGLGDSNNQSTLKKLTFEPHRSIKKVSSSKGSDGHTLAFTTEGEVFSWGDGDY 487
Query: 525 GQLGNNLGAHAQDKPKFVKG-LATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLG 701
G+LG+ + Q PK ++G L K V+ V+ G HS A+T G+LY+WG +G+ G G
Sbjct: 488 GKLGHG-NSSTQKYPKLIQGPLQGKVVVCVSAGYRHSAAVTEDGELYTWGEGDFGRLGHG 546
Query: 702 TISNKEMSPQHISSLIGVPIALIACGNNHTFVLSKSG-AVFGWGKNTHGXLG 854
SN P + + V ++CG++HT LSK G V+ +G +G LG
Sbjct: 547 D-SNSRNIPTLVKDISNV--GEVSCGSSHTIALSKDGRTVWSFGGGDNGKLG 595
Score = 106 bits (254), Expect = 1e-22
Identities = 64/223 (28%), Positives = 109/223 (48%), Gaps = 4/223 (1%)
Frame = +3
Query: 171 KMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGH-LYS 347
+++ WG L S ++ PTL K + ++ V+ G H++ LS G ++S
Sbjct: 531 ELYTWGEGDFGRLGHGDSNSRNI---PTLVK--DISNVGEVSCGSSHTIALSKDGRTVWS 585
Query: 348 CGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMG 527
G D G+LG +++ P ++E + I + G Q SLA+ GQ ++WG +
Sbjct: 586 FGGGDNGKLGHG-DTNRVYKPKVIEALQGMFIRKVCAGSQSSLALTSTGQVYAWGCGAC- 643
Query: 528 QLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTI 707
LG +PK ++ LA ++ V+ G H +AL++ ++Y+WG NS GQCG G
Sbjct: 644 -LGCGSSEATALRPKLIEELAATRIVDVSIGDSHCLALSHDNEVYAWGNNSMGQCGQGNS 702
Query: 708 SNKEMSPQHISSLIGVPIALIACGNNHTF---VLSKSGAVFGW 827
+ P+ +S L G+ I I+ G +H+ L + V W
Sbjct: 703 TGPITKPKKVSGLDGIAIQQISAGTSHSLAWTALPRDRQVVAW 745
Score = 103 bits (247), Expect = 8e-22
Identities = 66/230 (28%), Positives = 117/230 (50%), Gaps = 2/230 (0%)
Frame = +3
Query: 171 KMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSC 350
++F WG+ + +L G+ T K + + + V+AG HS ++ G LY+
Sbjct: 478 EVFSWGDGDYGKLG-HGNSSTQKYPK-LIQGPLQGKVVVCVSAGYRHSAAVTEDGELYTW 535
Query: 351 GNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQP-FSWGSDSMG 527
G D G+LG +S++ P LV+ + + ++CG H++A+ + G+ +S+G G
Sbjct: 536 GEGDFGRLGHG-DSNSRNIPTLVKDISN--VGEVSCGSSHTIALSKDGRTVWSFGGGDNG 592
Query: 528 QLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQC-GLGT 704
+LG+ + KPK ++ L + +V G+ S+ALT++G +Y+WG G C G G+
Sbjct: 593 KLGHG-DTNRVYKPKVIEALQGMFIRKVCAGSQSSLALTSTGQVYAWGC---GACLGCGS 648
Query: 705 ISNKEMSPQHISSLIGVPIALIACGNNHTFVLSKSGAVFGWGKNTHGXLG 854
+ P+ I L I ++ G++H LS V+ WG N+ G G
Sbjct: 649 SEATALRPKLIEELAATRIVDVSIGDSHCLALSHDNEVYAWGNNSMGQCG 698
Score = 101 bits (241), Expect = 4e-21
Identities = 58/217 (26%), Positives = 113/217 (52%), Gaps = 2/217 (0%)
Frame = +3
Query: 186 GNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDV 365
G ++ L + S + K T + + + + H+L + G ++S G+ D
Sbjct: 428 GKGSYGRLGLGDSNNQSTLKKLTFEPHRSIKKVSSSKGSDGHTLAFTTEGEVFSWGDGDY 487
Query: 366 GQLGRQTESDNGKNPALVE-TFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNN 542
G+LG S K P L++ + + ++ G +HS A+ E G+ ++WG G+LG+
Sbjct: 488 GKLGHGNSSTQ-KYPKLIQGPLQGKVVVCVSAGYRHSAAVTEDGELYTWGEGDFGRLGHG 546
Query: 543 LGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSG-DLYSWGANSYGQCGLGTISNKE 719
+++++ P VK ++ NV +V+CG+ H++AL+ G ++S+G G+ G G +N+
Sbjct: 547 -DSNSRNIPTLVKDIS--NVGEVSCGSSHTIALSKDGRTVWSFGGGDNGKLGHGD-TNRV 602
Query: 720 MSPQHISSLIGVPIALIACGNNHTFVLSKSGAVFGWG 830
P+ I +L G+ I + G+ + L+ +G V+ WG
Sbjct: 603 YKPKVIEALQGMFIRKVCAGSQSSLALTSTGQVYAWG 639
Score = 93.1 bits (221), Expect = 1e-18
Identities = 63/208 (30%), Positives = 106/208 (50%), Gaps = 1/208 (0%)
Frame = +3
Query: 171 KMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHL-YS 347
K+F +GN + L + + L + T E I VA G H+L +S G + ++
Sbjct: 4154 KLFTFGNGDYGRLGLGNTSNKKLPERVTAL---EGYQIGQVACGLNHTLAVSADGSMVWA 4210
Query: 348 CGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMG 527
G+ D G+LG + +P ++ I +ACG Q S+A+ + G +++G D +
Sbjct: 4211 FGDGDYGKLGLGNSTAKS-SPQKIDVLCGIGIKKVACGTQFSVALTKDGHVYTFGQDRLI 4269
Query: 528 QLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTI 707
L A ++P+ + LA + VA GA H++AL ++GD+Y+WG+NS GQ GLG
Sbjct: 4270 GLPEGR-ARNHNRPQQIPVLAGVIIEDVAVGAEHTLALASNGDVYAWGSNSEGQLGLGH- 4327
Query: 708 SNKEMSPQHISSLIGVPIALIACGNNHT 791
+N P ++ L G + I+ G H+
Sbjct: 4328 TNHVREPTLVTGLQGKNVRQISAGRCHS 4355
Score = 72.1 bits (169), Expect = 2e-12
Identities = 42/121 (34%), Positives = 63/121 (52%)
Frame = +3
Query: 282 IQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACG 461
I+ VA G S+ L+ GH+Y+ G + + L + + N P + I +A G
Sbjct: 4241 IKKVACGTQFSVALTKDGHVYTFGQDRLIGLP-EGRARNHNRPQQIPVLAGVIIEDVAVG 4299
Query: 462 LQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVAL 641
+H+LA+ G ++WGS+S GQLG H ++ P V GL KNV Q++ G HS A
Sbjct: 4300 AEHTLALASNGDVYAWGSNSEGQLGLGHTNHVRE-PTLVTGLQGKNVRQISAGRCHSAAW 4358
Query: 642 T 644
T
Sbjct: 4359 T 4359
Score = 66.9 bits (156), Expect = 9e-11
Identities = 47/180 (26%), Positives = 78/180 (43%), Gaps = 2/180 (1%)
Frame = +3
Query: 321 LSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQP 500
+S + +Y G+N QL T+ + P L +F D TI G + I G
Sbjct: 368 VSETCEVYVWGSNSSHQLVEGTQ-EKILQPKLAPSFSDA--QTIEAGQYCTFVISTDGSV 424
Query: 501 FSWGSDSMGQLG--NNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGA 674
+ G S G+LG ++ K F + K V H++A T G+++SWG
Sbjct: 425 RACGKGSYGRLGLGDSNNQSTLKKLTFEPHRSIKKVSSSKGSDGHTLAFTTEGEVFSWGD 484
Query: 675 NSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFVLSKSGAVFGWGKNTHGXLG 854
YG+ G G S ++ L G + ++ G H+ +++ G ++ WG+ G LG
Sbjct: 485 GDYGKLGHGNSSTQKYPKLIQGPLQGKVVVCVSAGYRHSAAVTEDGELYTWGEGDFGRLG 544
Score = 42.7 bits (96), Expect = 0.002
Identities = 28/98 (28%), Positives = 42/98 (42%)
Frame = +3
Query: 561 DKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHIS 740
D K++ G+ + ++ A L D+Y WGA +GQ L M P
Sbjct: 3968 DNSKWINGM-DEQIMSWATSRPEDWHLGGKCDVYLWGAGRHGQ--LAEAGRNVMVPAAAP 4024
Query: 741 SLIGVPIALIACGNNHTFVLSKSGAVFGWGKNTHGXLG 854
S + CG N TFV+ +G V G+ ++G LG
Sbjct: 4025 SF--SQAQQVICGQNCTFVIQANGTVLACGEGSYGRLG 4060
>AY337518-1|AAR00320.1| 1024|Homo sapiens HECT E3 ubiquitin ligase
protein.
Length = 1024
Score = 127 bits (307), Expect = 4e-29
Identities = 71/190 (37%), Positives = 102/190 (53%), Gaps = 2/190 (1%)
Frame = +3
Query: 291 VAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQH 470
+ G++HSL LS G L++ G N GQLG + + P +VE ++ I+ G H
Sbjct: 143 ITCGDYHSLALSKGGELFAWGQNLHGQLGVGRKFPSTTTPQIVEHLAGVPLAQISAGEAH 202
Query: 471 SLAIDEWGQPFSWGSDSMGQLGNNLG-AHAQDKPKFVKGLATKNVIQVACGAYHSVALTN 647
S A+ G +SWG + GQLG LG ++D P ++GL + V VACG HS LT
Sbjct: 203 STALSMSGNIYSWGKNECGQLG--LGHTESKDDPSLIEGLDNQKVEFVACGGSHSALLTQ 260
Query: 648 SGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFV-LSKSGAVFG 824
G L+++GA +GQ G + N E+ P ++ L+G + IACG HT +S G VF
Sbjct: 261 DGLLFTFGAGKHGQLGHNSTQN-ELRPCLVAELVGYRVTQIACGRWHTLAYVSDLGKVFS 319
Query: 825 WGKNTHGXLG 854
+G G LG
Sbjct: 320 FGSGKDGQLG 329
Score = 109 bits (263), Expect = 1e-23
Identities = 59/162 (36%), Positives = 88/162 (54%), Gaps = 2/162 (1%)
Frame = +3
Query: 375 GRQTESDNG--KNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLG 548
G+ E DN K+ ++ I I CG HSLA+ + G+ F+WG + GQLG
Sbjct: 116 GKPFEYDNYSMKHLRFESILQEKKIIQITCGDYHSLALSKGGELFAWGQNLHGQLGVGRK 175
Query: 549 AHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTISNKEMSP 728
+ P+ V+ LA + Q++ G HS AL+ SG++YSWG N GQ GLG +K+ P
Sbjct: 176 FPSTTTPQIVEHLAGVPLAQISAGEAHSTALSMSGNIYSWGKNECGQLGLGHTESKD-DP 234
Query: 729 QHISSLIGVPIALIACGNNHTFVLSKSGAVFGWGKNTHGXLG 854
I L + +ACG +H+ +L++ G +F +G HG LG
Sbjct: 235 SLIEGLDNQKVEFVACGGSHSALLTQDGLLFTFGAGKHGQLG 276
Score = 107 bits (257), Expect = 5e-23
Identities = 55/155 (35%), Positives = 83/155 (53%)
Frame = +3
Query: 390 SDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKP 569
S + P ++ K+ I ++ G +H L + G+PF + + SM L
Sbjct: 82 SGGARTPKCIKLGKNMKIHSVDQGAEHMLILSSDGKPFEYDNYSMKHL------------ 129
Query: 570 KFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLI 749
+F L K +IQ+ CG YHS+AL+ G+L++WG N +GQ G+G +PQ + L
Sbjct: 130 RFESILQEKKIIQITCGDYHSLALSKGGELFAWGQNLHGQLGVGRKFPSTTTPQIVEHLA 189
Query: 750 GVPIALIACGNNHTFVLSKSGAVFGWGKNTHGXLG 854
GVP+A I+ G H+ LS SG ++ WGKN G LG
Sbjct: 190 GVPLAQISAGEAHSTALSMSGNIYSWGKNECGQLG 224
Score = 66.1 bits (154), Expect = 2e-10
Identities = 45/137 (32%), Positives = 69/137 (50%), Gaps = 1/137 (0%)
Frame = +3
Query: 174 MFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCG 353
++ WG +L + ++ D P+L + ++ ++ VA G HS L+ G L++ G
Sbjct: 212 IYSWGKNECGQLGLGHTESKD---DPSLIEGLDNQKVEFVACGGSHSALLTQDGLLFTFG 268
Query: 354 NNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLA-IDEWGQPFSWGSDSMGQ 530
GQLG + + N P LV ++ IACG H+LA + + G+ FS+GS GQ
Sbjct: 269 AGKHGQLGHNS-TQNELRPCLVAELVGYRVTQIACGRWHTLAYVSDLGKVFSFGSGKDGQ 327
Query: 531 LGNNLGAHAQDKPKFVK 581
LGN G Q P VK
Sbjct: 328 LGNG-GTRDQLMPLPVK 343
>AF071172-1|AAD08657.1| 4834|Homo sapiens HERC2 protein.
Length = 4834
Score = 126 bits (303), Expect = 1e-28
Identities = 74/233 (31%), Positives = 118/233 (50%), Gaps = 5/233 (2%)
Frame = +3
Query: 171 KMFCWGNATHHELC-IDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYS 347
K+F WG +L + GS+I P+ S+ + ++ VA G ++ G +Y+
Sbjct: 2960 KVFVWGLNDKDQLGGLKGSKIK----VPSFSETLSALNVVQVAGGSKSLFAVTVEGKVYA 3015
Query: 348 CGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIAC--GLQHSLAIDEWGQPFSWGSDS 521
CG G+LG S P + + +A G +H+ A+ G+ FSWG
Sbjct: 3016 CGEATNGRLGLGISSGTVPIPRQITALSSYVVKKVAVHSGGRHATALTVDGKVFSWGEGD 3075
Query: 522 MGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLG 701
G+LG+ + DKP+ ++ L TK + +ACG+ HS ALT+SG+LY+WG YG+ G G
Sbjct: 3076 DGKLGHFSRMNC-DKPRLIEALKTKRIRDIACGSSHSAALTSSGELYTWGLGEYGRLGHG 3134
Query: 702 TISNKEMSPQHISSLIGVPIALIACGNN--HTFVLSKSGAVFGWGKNTHGXLG 854
+ ++ P+ + L+G + +ACG+ T L+ G VF WG G LG
Sbjct: 3135 D-NTTQLKPKMVKVLLGHRVIQVACGSRDAQTLALTDEGLVFSWGDGDFGKLG 3186
Score = 123 bits (297), Expect = 7e-28
Identities = 73/191 (38%), Positives = 103/191 (53%), Gaps = 2/191 (1%)
Frame = +3
Query: 288 AVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQ 467
AV +G H+ L+ G ++S G D G+LG + + K P L+E K I IACG
Sbjct: 3051 AVHSGGRHATALTVDGKVFSWGEGDDGKLGHFSRMNCDK-PRLIEALKTKRIRDIACGSS 3109
Query: 468 HSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAY--HSVAL 641
HS A+ G+ ++WG G+LG+ Q KPK VK L VIQVACG+ ++AL
Sbjct: 3110 HSAALTSSGELYTWGLGEYGRLGHGDNT-TQLKPKMVKVLLGHRVIQVACGSRDAQTLAL 3168
Query: 642 TNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFVLSKSGAVF 821
T+ G ++SWG +G+ G G + PQ+I L G + I CG + L+KSG V+
Sbjct: 3169 TDEGLVFSWGDGDFGKLGRGGSEGCNI-PQNIERLNGQGVCQIECGAQFSLALTKSGVVW 3227
Query: 822 GWGKNTHGXLG 854
WGK + LG
Sbjct: 3228 TWGKGDYFRLG 3238
Score = 122 bits (295), Expect = 1e-27
Identities = 75/230 (32%), Positives = 116/230 (50%), Gaps = 2/230 (0%)
Frame = +3
Query: 171 KMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSC 350
K+F WG +L D KP L + ++ I+ +A G HS L++SG LY+
Sbjct: 3067 KVFSWGEGDDGKLGHFSRMNCD---KPRLIEALKTKRIRDIACGSSHSAALTSSGELYTW 3123
Query: 351 GNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQ--HSLAIDEWGQPFSWGSDSM 524
G + G+LG + K P +V+ + +ACG + +LA+ + G FSWG
Sbjct: 3124 GLGEYGRLGHGDNTTQLK-PKMVKVLLGHRVIQVACGSRDAQTLALTDEGLVFSWGDGDF 3182
Query: 525 GQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGT 704
G+LG G+ + P+ ++ L + V Q+ CGA S+ALT SG +++WG Y + G G+
Sbjct: 3183 GKLGRG-GSEGCNIPQNIERLNGQGVCQIECGAQFSLALTKSGVVWTWGKGDYFRLGHGS 3241
Query: 705 ISNKEMSPQHISSLIGVPIALIACGNNHTFVLSKSGAVFGWGKNTHGXLG 854
+ PQ + L G I +A G H ++ SG V+ WG N HG G
Sbjct: 3242 DVHVR-KPQVVEGLRGKKIVHVAVGALHCLAVTDSGQVYAWGDNDHGQQG 3290
Score = 117 bits (282), Expect = 5e-26
Identities = 73/220 (33%), Positives = 115/220 (52%), Gaps = 2/220 (0%)
Frame = +3
Query: 138 SSY*KKLQNYKKMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAG--EFH 311
SS+ L + +++ WG + L G T L KP + K + VA G +
Sbjct: 3108 SSHSAALTSSGELYTWGLGEYGRLG-HGDNTTQL--KPKMVKVLLGHRVIQVACGSRDAQ 3164
Query: 312 SLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEW 491
+L L++ G ++S G+ D G+LGR S+ P +E + I CG Q SLA+ +
Sbjct: 3165 TLALTDEGLVFSWGDGDFGKLGRGG-SEGCNIPQNIERLNGQGVCQIECGAQFSLALTKS 3223
Query: 492 GQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWG 671
G ++WG +LG+ H + KP+ V+GL K ++ VA GA H +A+T+SG +Y+WG
Sbjct: 3224 GVVWTWGKGDYFRLGHGSDVHVR-KPQVVEGLRGKKIVHVAVGALHCLAVTDSGQVYAWG 3282
Query: 672 ANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHT 791
N +GQ G GT + P + L G I +ACG++H+
Sbjct: 3283 DNDHGQQGNGT-TTVNRKPTLVQGLEGQKITRVACGSSHS 3321
Score = 115 bits (277), Expect = 2e-25
Identities = 66/214 (30%), Positives = 114/214 (53%), Gaps = 2/214 (0%)
Frame = +3
Query: 174 MFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVA--AGEFHSLYLSNSGHLYS 347
++ WG + L G ++ +KP L + + + +A +G+ +L L++ ++S
Sbjct: 4112 LYTWGKGRYGRL---GHSDSEDQLKPKLVEALQGHRVVDIACGSGDAQTLCLTDDDTVWS 4168
Query: 348 CGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMG 527
G+ D G+LGR SD K P +++ + + CG Q S+A+ + G ++WG
Sbjct: 4169 WGDGDYGKLGRGG-SDGCKVPMKIDSLTGLGVVKVECGSQFSVALTKSGAVYTWGKGDYH 4227
Query: 528 QLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTI 707
+LG+ H + +P+ V+GL K VI +A G+ H V T G++Y+WG N GQ G GT
Sbjct: 4228 RLGHGSDDHVR-RPRQVQGLQGKKVIAIATGSLHCVCCTEDGEVYTWGDNDEGQLGDGT- 4285
Query: 708 SNKEMSPQHISSLIGVPIALIACGNNHTFVLSKS 809
+N P+ +++L G + +ACG+ HT S S
Sbjct: 4286 TNAIQRPRLVAALQGKKVNRVACGSAHTLAWSTS 4319
Score = 112 bits (270), Expect = 1e-24
Identities = 72/235 (30%), Positives = 110/235 (46%), Gaps = 2/235 (0%)
Frame = +3
Query: 156 LQNYKKMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSG 335
L + +++ WG A +L D +P + + + VAAG HS ++ +G
Sbjct: 4054 LSSEGEVYSWGEAEDGKLGHGNRSPCD---RPRVIESLRGIEVVDVAAGGAHSACVTAAG 4110
Query: 336 HLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGL--QHSLAIDEWGQPFSW 509
LY+ G G+LG D K P LVE + + IACG +L + + +SW
Sbjct: 4111 DLYTWGKGRYGRLGHSDSEDQLK-PKLVEALQGHRVVDIACGSGDAQTLCLTDDDTVWSW 4169
Query: 510 GSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQ 689
G G+LG G+ P + L V++V CG+ SVALT SG +Y+WG Y +
Sbjct: 4170 GDGDYGKLGRG-GSDGCKVPMKIDSLTGLGVVKVECGSQFSVALTKSGAVYTWGKGDYHR 4228
Query: 690 CGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFVLSKSGAVFGWGKNTHGXLG 854
G G+ + P+ + L G + IA G+ H ++ G V+ WG N G LG
Sbjct: 4229 LGHGS-DDHVRRPRQVQGLQGKKVIAIATGSLHCVCCTEDGEVYTWGDNDEGQLG 4282
Score = 108 bits (260), Expect = 2e-23
Identities = 70/223 (31%), Positives = 112/223 (50%), Gaps = 1/223 (0%)
Frame = +3
Query: 138 SSY*KKLQNYKKMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQ-AVAAGEFHS 314
S+Y + +++ WG + L S+ D I ++ K I A +G+ +
Sbjct: 560 STYSAAITAEGELYTWGRGNYGRLGHGSSE--DEAIPMLVAGLKGLKVIDVACGSGDAQT 617
Query: 315 LYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWG 494
L ++ +G ++S G+ D G+LGR SD K P L+E +D + + CG Q S+A+ + G
Sbjct: 618 LAVTENGQVWSWGDGDYGKLGRGG-SDGCKTPKLIEKLQDLDVVKVRCGSQFSIALTKDG 676
Query: 495 QPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGA 674
Q +SWG +LG+ H + PK ++GL K VI VA G+ H +ALT +++SWG+
Sbjct: 677 QVYSWGKGDNQRLGHGTEEHVR-YPKLLEGLQGKKVIDVAAGSTHCLALTEDSEVHSWGS 735
Query: 675 NSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFVLS 803
N Q T+ + P + L I IACG +F S
Sbjct: 736 NDQCQ-HFDTLRVTKPEPAALPGLDTKHIVGIACGPAQSFAWS 777
Score = 102 bits (245), Expect = 1e-21
Identities = 67/212 (31%), Positives = 109/212 (51%), Gaps = 8/212 (3%)
Frame = +3
Query: 243 IKPTLSKWKESDHIQAVAAGE--FHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPAL 416
+ P L + S +I +AA H L L+ +G +YS G D G+LG ++ + P +
Sbjct: 482 LAPQLVQGLASRNIVKIAAHSDGHHYLALAATGEVYSWGCGDGGRLGHG-DTVPLEEPKV 540
Query: 417 VETFKDCT----ISTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKG 584
+ F + IACG +S AI G+ ++WG + G+LG+ + + P V G
Sbjct: 541 ISAFSGKQAGKHVVHIACGSTYSAAITAEGELYTWGRGNYGRLGHG-SSEDEAIPMLVAG 599
Query: 585 LATKNVIQVACGA--YHSVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVP 758
L VI VACG+ ++A+T +G ++SWG YG+ G G S+ +P+ I L +
Sbjct: 600 LKGLKVIDVACGSGDAQTLAVTENGQVWSWGDGDYGKLGRGG-SDGCKTPKLIEKLQDLD 658
Query: 759 IALIACGNNHTFVLSKSGAVFGWGKNTHGXLG 854
+ + CG+ + L+K G V+ WGK + LG
Sbjct: 659 VVKVRCGSQFSIALTKDGQVYSWGKGDNQRLG 690
Score = 101 bits (241), Expect = 4e-21
Identities = 63/190 (33%), Positives = 99/190 (52%), Gaps = 5/190 (2%)
Frame = +3
Query: 300 GEFHSLYLSNSGHLYSCGNNDVGQLG-RQTESDNGKNPALVETFKDCTISTIAC--GLQH 470
GE ++ G LY+ G G+LG TES + P L+E+ + I +A G +H
Sbjct: 3993 GEQTLFAVTADGKLYATGYGAGGRLGIGGTESVS--TPTLLESIQHVFIKKVAVNSGGKH 4050
Query: 471 SLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNS 650
LA+ G+ +SWG G+LG+ + D+P+ ++ L V+ VA G HS +T +
Sbjct: 4051 CLALSSEGEVYSWGEAEDGKLGHGNRSPC-DRPRVIESLRGIEVVDVAAGGAHSACVTAA 4109
Query: 651 GDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNN--HTFVLSKSGAVFG 824
GDLY+WG YG+ G + S ++ P+ + +L G + IACG+ T L+ V+
Sbjct: 4110 GDLYTWGKGRYGRLG-HSDSEDQLKPKLVEALQGHRVVDIACGSGDAQTLCLTDDDTVWS 4168
Query: 825 WGKNTHGXLG 854
WG +G LG
Sbjct: 4169 WGDGDYGKLG 4178
Score = 92.7 bits (220), Expect = 2e-18
Identities = 54/171 (31%), Positives = 90/171 (52%), Gaps = 8/171 (4%)
Frame = +3
Query: 366 GQLGRQTESDNGKNPALVETFKDCTISTIACGLQ--HSLAIDEWGQPFSWGSDSMGQLGN 539
G++ Q + + P LV+ I IA H LA+ G+ +SWG G+LG+
Sbjct: 470 GRVYTQAYNSDTLAPQLVQGLASRNIVKIAAHSDGHHYLALAATGEVYSWGCGDGGRLGH 529
Query: 540 NLGAHAQDKPKFVKGL----ATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTI 707
++PK + A K+V+ +ACG+ +S A+T G+LY+WG +YG+ G G+
Sbjct: 530 G-DTVPLEEPKVISAFSGKQAGKHVVHIACGSTYSAAITAEGELYTWGRGNYGRLGHGS- 587
Query: 708 SNKEMSPQHISSLIGVPIALIACGNN--HTFVLSKSGAVFGWGKNTHGXLG 854
S E P ++ L G+ + +ACG+ T ++++G V+ WG +G LG
Sbjct: 588 SEDEAIPMLVAGLKGLKVIDVACGSGDAQTLAVTENGQVWSWGDGDYGKLG 638
Score = 78.6 bits (185), Expect = 3e-14
Identities = 54/183 (29%), Positives = 88/183 (48%), Gaps = 2/183 (1%)
Frame = +3
Query: 312 SLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEW 491
+L SG +Y G+N GQLG E K P E + G Q A+
Sbjct: 3945 TLSAGGSGTIYGWGHNHRGQLG-GIEGAKVKVPTPCEALATLRPVQLIGGEQTLFAVTAD 4003
Query: 492 GQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVA--CGAYHSVALTNSGDLYS 665
G+ ++ G + G+LG G + P ++ + + +VA G H +AL++ G++YS
Sbjct: 4004 GKLYATGYGAGGRLGIG-GTESVSTPTLLESIQHVFIKKVAVNSGGKHCLALSSEGEVYS 4062
Query: 666 WGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFVLSKSGAVFGWGKNTHG 845
WG G+ G G S + P+ I SL G+ + +A G H+ ++ +G ++ WGK +G
Sbjct: 4063 WGEAEDGKLGHGNRSPCD-RPRVIESLRGIEVVDVAAGGAHSACVTAAGDLYTWGKGRYG 4121
Query: 846 XLG 854
LG
Sbjct: 4122 RLG 4124
Score = 76.2 bits (179), Expect = 1e-13
Identities = 48/157 (30%), Positives = 79/157 (50%)
Frame = +3
Query: 174 MFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCG 353
+F WG+ +L GS+ ++ P + + + G SL L+ SG +++ G
Sbjct: 3174 VFSWGDGDFGKLGRGGSEGCNI---PQNIERLNGQGVCQIECGAQFSLALTKSGVVWTWG 3230
Query: 354 NNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQL 533
D +LG ++ + + P +VE + I +A G H LA+ + GQ ++WG + GQ
Sbjct: 3231 KGDYFRLGHGSDV-HVRKPQVVEGLRGKKIVHVAVGALHCLAVTDSGQVYAWGDNDHGQQ 3289
Query: 534 GNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALT 644
GN KP V+GL + + +VACG+ HSVA T
Sbjct: 3290 GNGTTT-VNRKPTLVQGLEGQKITRVACGSSHSVAWT 3325
Score = 37.5 bits (83), Expect = 0.061
Identities = 27/94 (28%), Positives = 41/94 (43%), Gaps = 2/94 (2%)
Frame = +3
Query: 579 KGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVP 758
+GLA V Q+AC + L+ +G +Y+ NS ++PQ + L
Sbjct: 446 EGLANLGVTQIACAEKRFLILSRNGRVYTQAYNS-----------DTLAPQLVQGLASRN 494
Query: 759 IALIAC--GNNHTFVLSKSGAVFGWGKNTHGXLG 854
I IA +H L+ +G V+ WG G LG
Sbjct: 495 IVKIAAHSDGHHYLALAATGEVYSWGCGDGGRLG 528
>BC029052-1|AAH29052.1| 551|Homo sapiens regulator of chromosome
condensation (RCC1) and BTB (POZ) domain containing pro
protein.
Length = 551
Score = 125 bits (301), Expect = 2e-28
Identities = 64/184 (34%), Positives = 106/184 (57%), Gaps = 2/184 (1%)
Frame = +3
Query: 309 HSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVET-FKDCTISTIACGLQHSLAID 485
H + + G +++ G+N QLG T +++G P + T + + +ACG HSL +
Sbjct: 110 HIVLATTEGEVFTWGHNAYSQLGNGT-TNHGLVPCHISTNLSNKQVIEVACGSYHSLVLT 168
Query: 486 EWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKG-LATKNVIQVACGAYHSVALTNSGDLY 662
G+ F+WG ++ GQ+G+ + Q P+ V G L K V+ +ACG +A+ ++G++Y
Sbjct: 169 SDGEVFAWGYNNSGQVGSGSTVN-QPIPRRVTGCLQNKVVVTIACGQMCCMAVVDTGEVY 227
Query: 663 SWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFVLSKSGAVFGWGKNTH 842
WG N GQ GLG S + +P +++L G+ + +ACG HT VL+ G V+ WG N++
Sbjct: 228 VWGYNGNGQLGLGN-SGNQPTPCRVAALQGIRVQRVACGYAHTLVLTDEGQVYAWGANSY 286
Query: 843 GXLG 854
G LG
Sbjct: 287 GQLG 290
Score = 115 bits (276), Expect = 3e-25
Identities = 70/223 (31%), Positives = 117/223 (52%), Gaps = 2/223 (0%)
Frame = +3
Query: 171 KMFCWGNATHHELCIDGSQITDLVIKPT-LSKWKESDHIQAVAAGEFHSLYLSNSGHLYS 347
++F WG+ + +L G+ T+ + P +S + + VA G +HSL L++ G +++
Sbjct: 119 EVFTWGHNAYSQL---GNGTTNHGLVPCHISTNLSNKQVIEVACGSYHSLVLTSDGEVFA 175
Query: 348 CGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMG 527
G N+ GQ+G + + + ++ + TIACG +A+ + G+ + WG + G
Sbjct: 176 WGYNNSGQVGSGSTVNQPIPRRVTGCLQNKVVVTIACGQMCCMAVVDTGEVYVWGYNGNG 235
Query: 528 QLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTI 707
QLG + Q P V L V +VACG H++ LT+ G +Y+WGANSYGQ G G
Sbjct: 236 QLGLGNSGN-QPTPCRVAALQGIRVQRVACGYAHTLVLTDEGQVYAWGANSYGQLGTGNK 294
Query: 708 SNKEMSPQHISSLIGVPIALIACGNNHTFVL-SKSGAVFGWGK 833
SN+ P ++ I + AC + HT ++ G V+ WG+
Sbjct: 295 SNQSY-PTPVTVEKDRIIEIAACHSTHTSAAKTQGGHVYMWGQ 336
Score = 99.5 bits (237), Expect = 1e-20
Identities = 55/181 (30%), Positives = 91/181 (50%), Gaps = 1/181 (0%)
Frame = +3
Query: 315 LYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGL-QHSLAIDEW 491
LY + + ++ G N G LG + + P +++ I+ ++ G H +
Sbjct: 59 LYTTVNDEIFVLGTNCCGCLGLG-DVQSTIEPRRLDSLNGKKIACLSYGSGPHIVLATTE 117
Query: 492 GQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWG 671
G+ F+WG ++ QLGN H L+ K VI+VACG+YHS+ LT+ G++++WG
Sbjct: 118 GEVFTWGHNAYSQLGNGTTNHGLVPCHISTNLSNKQVIEVACGSYHSLVLTSDGEVFAWG 177
Query: 672 ANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFVLSKSGAVFGWGKNTHGXL 851
N+ GQ G G+ N+ + + L + IACG + +G V+ WG N +G L
Sbjct: 178 YNNSGQVGSGSTVNQPIPRRVTGCLQNKVVVTIACGQMCCMAVVDTGEVYVWGYNGNGQL 237
Query: 852 G 854
G
Sbjct: 238 G 238
>AY341245-1|AAP88928.1| 551|Homo sapiens chromosome condensation
1-like protein.
Length = 551
Score = 125 bits (301), Expect = 2e-28
Identities = 64/184 (34%), Positives = 106/184 (57%), Gaps = 2/184 (1%)
Frame = +3
Query: 309 HSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVET-FKDCTISTIACGLQHSLAID 485
H + + G +++ G+N QLG T +++G P + T + + +ACG HSL +
Sbjct: 110 HIVLATTEGEVFTWGHNAYSQLGNGT-TNHGLVPCHISTNLSNKQVIEVACGSYHSLVLT 168
Query: 486 EWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKG-LATKNVIQVACGAYHSVALTNSGDLY 662
G+ F+WG ++ GQ+G+ + Q P+ V G L K V+ +ACG +A+ ++G++Y
Sbjct: 169 SDGEVFAWGYNNSGQVGSGSTVN-QPIPRRVTGCLQNKVVVTIACGQMCCMAVVDTGEVY 227
Query: 663 SWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFVLSKSGAVFGWGKNTH 842
WG N GQ GLG S + +P +++L G+ + +ACG HT VL+ G V+ WG N++
Sbjct: 228 VWGYNGNGQLGLGN-SGNQPTPCRVAALQGIRVQRVACGYAHTLVLTDEGQVYAWGANSY 286
Query: 843 GXLG 854
G LG
Sbjct: 287 GQLG 290
Score = 115 bits (276), Expect = 3e-25
Identities = 70/223 (31%), Positives = 117/223 (52%), Gaps = 2/223 (0%)
Frame = +3
Query: 171 KMFCWGNATHHELCIDGSQITDLVIKPT-LSKWKESDHIQAVAAGEFHSLYLSNSGHLYS 347
++F WG+ + +L G+ T+ + P +S + + VA G +HSL L++ G +++
Sbjct: 119 EVFTWGHNAYSQL---GNGTTNHGLVPCHISTNLSNKQVIEVACGSYHSLVLTSDGEVFA 175
Query: 348 CGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMG 527
G N+ GQ+G + + + ++ + TIACG +A+ + G+ + WG + G
Sbjct: 176 WGYNNSGQVGSGSTVNQPIPRRVTGCLQNKVVVTIACGQMCCMAVVDTGEVYVWGYNGNG 235
Query: 528 QLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTI 707
QLG + Q P V L V +VACG H++ LT+ G +Y+WGANSYGQ G G
Sbjct: 236 QLGLGNSGN-QPTPCRVAALQGIRVQRVACGYAHTLVLTDEGQVYAWGANSYGQLGTGNK 294
Query: 708 SNKEMSPQHISSLIGVPIALIACGNNHTFVL-SKSGAVFGWGK 833
SN+ P ++ I + AC + HT ++ G V+ WG+
Sbjct: 295 SNQSY-PTPVTVEKDRIIEIAACHSTHTSAAKTQGGHVYMWGQ 336
Score = 99.5 bits (237), Expect = 1e-20
Identities = 55/181 (30%), Positives = 91/181 (50%), Gaps = 1/181 (0%)
Frame = +3
Query: 315 LYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGL-QHSLAIDEW 491
LY + + ++ G N G LG + + P +++ I+ ++ G H +
Sbjct: 59 LYTTVNDEIFVLGTNCCGCLGLG-DVQSTIEPRRLDSLNGKKIACLSYGSGPHIVLATTE 117
Query: 492 GQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWG 671
G+ F+WG ++ QLGN H L+ K VI+VACG+YHS+ LT+ G++++WG
Sbjct: 118 GEVFTWGHNAYSQLGNGTTNHGLVPCHISTNLSNKQVIEVACGSYHSLVLTSDGEVFAWG 177
Query: 672 ANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFVLSKSGAVFGWGKNTHGXL 851
N+ GQ G G+ N+ + + L + IACG + +G V+ WG N +G L
Sbjct: 178 YNNSGQVGSGSTVNQPIPRRVTGCLQNKVVVTIACGQMCCMAVVDTGEVYVWGYNGNGQL 237
Query: 852 G 854
G
Sbjct: 238 G 238
>AL157813-1|CAH70795.1| 551|Homo sapiens regulator of chromosome
condensation (RCC1) and BTB (POZ) domain containing pro
protein.
Length = 551
Score = 125 bits (301), Expect = 2e-28
Identities = 64/184 (34%), Positives = 106/184 (57%), Gaps = 2/184 (1%)
Frame = +3
Query: 309 HSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVET-FKDCTISTIACGLQHSLAID 485
H + + G +++ G+N QLG T +++G P + T + + +ACG HSL +
Sbjct: 110 HIVLATTEGEVFTWGHNAYSQLGNGT-TNHGLVPCHISTNLSNKQVIEVACGSYHSLVLT 168
Query: 486 EWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKG-LATKNVIQVACGAYHSVALTNSGDLY 662
G+ F+WG ++ GQ+G+ + Q P+ V G L K V+ +ACG +A+ ++G++Y
Sbjct: 169 SDGEVFAWGYNNSGQVGSGSTVN-QPIPRRVTGCLQNKVVVTIACGQMCCMAVVDTGEVY 227
Query: 663 SWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFVLSKSGAVFGWGKNTH 842
WG N GQ GLG S + +P +++L G+ + +ACG HT VL+ G V+ WG N++
Sbjct: 228 VWGYNGNGQLGLGN-SGNQPTPCRVAALQGIRVQRVACGYAHTLVLTDEGQVYAWGANSY 286
Query: 843 GXLG 854
G LG
Sbjct: 287 GQLG 290
Score = 115 bits (276), Expect = 3e-25
Identities = 70/223 (31%), Positives = 117/223 (52%), Gaps = 2/223 (0%)
Frame = +3
Query: 171 KMFCWGNATHHELCIDGSQITDLVIKPT-LSKWKESDHIQAVAAGEFHSLYLSNSGHLYS 347
++F WG+ + +L G+ T+ + P +S + + VA G +HSL L++ G +++
Sbjct: 119 EVFTWGHNAYSQL---GNGTTNHGLVPCHISTNLSNKQVIEVACGSYHSLVLTSDGEVFA 175
Query: 348 CGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMG 527
G N+ GQ+G + + + ++ + TIACG +A+ + G+ + WG + G
Sbjct: 176 WGYNNSGQVGSGSTVNQPIPRRVTGCLQNKVVVTIACGQMCCMAVVDTGEVYVWGYNGNG 235
Query: 528 QLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTI 707
QLG + Q P V L V +VACG H++ LT+ G +Y+WGANSYGQ G G
Sbjct: 236 QLGLGNSGN-QPTPCRVAALQGIRVQRVACGYAHTLVLTDEGQVYAWGANSYGQLGTGNK 294
Query: 708 SNKEMSPQHISSLIGVPIALIACGNNHTFVL-SKSGAVFGWGK 833
SN+ P ++ I + AC + HT ++ G V+ WG+
Sbjct: 295 SNQSY-PTPVTVEKDRIIEIAACHSTHTSAAKTQGGHVYMWGQ 336
Score = 99.5 bits (237), Expect = 1e-20
Identities = 55/181 (30%), Positives = 91/181 (50%), Gaps = 1/181 (0%)
Frame = +3
Query: 315 LYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGL-QHSLAIDEW 491
LY + + ++ G N G LG + + P +++ I+ ++ G H +
Sbjct: 59 LYTTVNDEIFVLGTNCCGCLGLG-DVQSTIEPRRLDSLNGKKIACLSYGSGPHIVLATTE 117
Query: 492 GQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWG 671
G+ F+WG ++ QLGN H L+ K VI+VACG+YHS+ LT+ G++++WG
Sbjct: 118 GEVFTWGHNAYSQLGNGTTNHGLVPCHISTNLSNKQVIEVACGSYHSLVLTSDGEVFAWG 177
Query: 672 ANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFVLSKSGAVFGWGKNTHGXL 851
N+ GQ G G+ N+ + + L + IACG + +G V+ WG N +G L
Sbjct: 178 YNNSGQVGSGSTVNQPIPRRVTGCLQNKVVVTIACGQMCCMAVVDTGEVYVWGYNGNGQL 237
Query: 852 G 854
G
Sbjct: 238 G 238
>AF060219-1|AAC79987.1| 551|Homo sapiens RCC1-like G exchanging
factor RLG protein.
Length = 551
Score = 125 bits (301), Expect = 2e-28
Identities = 64/184 (34%), Positives = 106/184 (57%), Gaps = 2/184 (1%)
Frame = +3
Query: 309 HSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVET-FKDCTISTIACGLQHSLAID 485
H + + G +++ G+N QLG T +++G P + T + + +ACG HSL +
Sbjct: 110 HIVLATTEGEVFTWGHNAYSQLGNGT-TNHGLVPCHISTNLSNKQVIEVACGSYHSLVLT 168
Query: 486 EWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKG-LATKNVIQVACGAYHSVALTNSGDLY 662
G+ F+WG ++ GQ+G+ + Q P+ V G L K V+ +ACG +A+ ++G++Y
Sbjct: 169 SDGEVFAWGYNNSGQVGSGSTVN-QPIPRRVTGCLQNKVVVTIACGQMCCMAVVDTGEVY 227
Query: 663 SWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFVLSKSGAVFGWGKNTH 842
WG N GQ GLG S + +P +++L G+ + +ACG HT VL+ G V+ WG N++
Sbjct: 228 VWGYNGNGQLGLGN-SGNQPTPCRVAALQGIRVQRVACGYAHTLVLTDEGQVYAWGANSY 286
Query: 843 GXLG 854
G LG
Sbjct: 287 GQLG 290
Score = 115 bits (276), Expect = 3e-25
Identities = 70/223 (31%), Positives = 117/223 (52%), Gaps = 2/223 (0%)
Frame = +3
Query: 171 KMFCWGNATHHELCIDGSQITDLVIKPT-LSKWKESDHIQAVAAGEFHSLYLSNSGHLYS 347
++F WG+ + +L G+ T+ + P +S + + VA G +HSL L++ G +++
Sbjct: 119 EVFTWGHNAYSQL---GNGTTNHGLVPCHISTNLSNKQVIEVACGSYHSLVLTSDGEVFA 175
Query: 348 CGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMG 527
G N+ GQ+G + + + ++ + TIACG +A+ + G+ + WG + G
Sbjct: 176 WGYNNSGQVGSGSTVNQPIPRRVTGCLQNKVVVTIACGQMCCMAVVDTGEVYVWGYNGNG 235
Query: 528 QLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTI 707
QLG + Q P V L V +VACG H++ LT+ G +Y+WGANSYGQ G G
Sbjct: 236 QLGLGNSGN-QPTPCRVAALQGIRVQRVACGYAHTLVLTDEGQVYAWGANSYGQLGTGNK 294
Query: 708 SNKEMSPQHISSLIGVPIALIACGNNHTFVL-SKSGAVFGWGK 833
SN+ P ++ I + AC + HT ++ G V+ WG+
Sbjct: 295 SNQSY-PTPVTVEKDRIIEIAACHSTHTSAAKTQGGHVYMWGQ 336
Score = 99.5 bits (237), Expect = 1e-20
Identities = 55/181 (30%), Positives = 91/181 (50%), Gaps = 1/181 (0%)
Frame = +3
Query: 315 LYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGL-QHSLAIDEW 491
LY + + ++ G N G LG + + P +++ I+ ++ G H +
Sbjct: 59 LYTTVNDEIFVLGTNCCGCLGLG-DVQSTIEPRRLDSLNGKKIACLSYGSGPHIVLATTE 117
Query: 492 GQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWG 671
G+ F+WG ++ QLGN H L+ K VI+VACG+YHS+ LT+ G++++WG
Sbjct: 118 GEVFTWGHNAYSQLGNGTTNHGLVPCHISTNLSNKQVIEVACGSYHSLVLTSDGEVFAWG 177
Query: 672 ANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFVLSKSGAVFGWGKNTHGXL 851
N+ GQ G G+ N+ + + L + IACG + +G V+ WG N +G L
Sbjct: 178 YNNSGQVGSGSTVNQPIPRRVTGCLQNKVVVTIACGQMCCMAVVDTGEVYVWGYNGNGQL 237
Query: 852 G 854
G
Sbjct: 238 G 238
>AB209543-1|BAD92780.1| 556|Homo sapiens RCC1-like G exchanging
factor RLG variant protein.
Length = 556
Score = 125 bits (301), Expect = 2e-28
Identities = 64/184 (34%), Positives = 106/184 (57%), Gaps = 2/184 (1%)
Frame = +3
Query: 309 HSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVET-FKDCTISTIACGLQHSLAID 485
H + + G +++ G+N QLG T +++G P + T + + +ACG HSL +
Sbjct: 115 HIVLATTEGEVFTWGHNAYSQLGNGT-TNHGLVPCHISTNLSNKQVIEVACGSYHSLVLT 173
Query: 486 EWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKG-LATKNVIQVACGAYHSVALTNSGDLY 662
G+ F+WG ++ GQ+G+ + Q P+ V G L K V+ +ACG +A+ ++G++Y
Sbjct: 174 SDGEVFAWGYNNSGQVGSGSTVN-QPIPRRVTGCLQNKVVVTIACGQMCCMAVVDTGEVY 232
Query: 663 SWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFVLSKSGAVFGWGKNTH 842
WG N GQ GLG S + +P +++L G+ + +ACG HT VL+ G V+ WG N++
Sbjct: 233 VWGYNGNGQLGLGN-SGNQPTPCRVAALQGIRVQRVACGYAHTLVLTDEGQVYAWGANSY 291
Query: 843 GXLG 854
G LG
Sbjct: 292 GQLG 295
Score = 115 bits (276), Expect = 3e-25
Identities = 70/223 (31%), Positives = 117/223 (52%), Gaps = 2/223 (0%)
Frame = +3
Query: 171 KMFCWGNATHHELCIDGSQITDLVIKPT-LSKWKESDHIQAVAAGEFHSLYLSNSGHLYS 347
++F WG+ + +L G+ T+ + P +S + + VA G +HSL L++ G +++
Sbjct: 124 EVFTWGHNAYSQL---GNGTTNHGLVPCHISTNLSNKQVIEVACGSYHSLVLTSDGEVFA 180
Query: 348 CGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMG 527
G N+ GQ+G + + + ++ + TIACG +A+ + G+ + WG + G
Sbjct: 181 WGYNNSGQVGSGSTVNQPIPRRVTGCLQNKVVVTIACGQMCCMAVVDTGEVYVWGYNGNG 240
Query: 528 QLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTI 707
QLG + Q P V L V +VACG H++ LT+ G +Y+WGANSYGQ G G
Sbjct: 241 QLGLGNSGN-QPTPCRVAALQGIRVQRVACGYAHTLVLTDEGQVYAWGANSYGQLGTGNK 299
Query: 708 SNKEMSPQHISSLIGVPIALIACGNNHTFVL-SKSGAVFGWGK 833
SN+ P ++ I + AC + HT ++ G V+ WG+
Sbjct: 300 SNQSY-PTPVTVEKDRIIEIAACHSTHTSAAKTQGGHVYMWGQ 341
Score = 99.5 bits (237), Expect = 1e-20
Identities = 55/181 (30%), Positives = 91/181 (50%), Gaps = 1/181 (0%)
Frame = +3
Query: 315 LYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGL-QHSLAIDEW 491
LY + + ++ G N G LG + + P +++ I+ ++ G H +
Sbjct: 64 LYTTVNDEIFVLGTNCCGCLGLG-DVQSTIEPRRLDSLNGKKIACLSYGSGPHIVLATTE 122
Query: 492 GQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWG 671
G+ F+WG ++ QLGN H L+ K VI+VACG+YHS+ LT+ G++++WG
Sbjct: 123 GEVFTWGHNAYSQLGNGTTNHGLVPCHISTNLSNKQVIEVACGSYHSLVLTSDGEVFAWG 182
Query: 672 ANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFVLSKSGAVFGWGKNTHGXL 851
N+ GQ G G+ N+ + + L + IACG + +G V+ WG N +G L
Sbjct: 183 YNNSGQVGSGSTVNQPIPRRVTGCLQNKVVVTIACGQMCCMAVVDTGEVYVWGYNGNGQL 242
Query: 852 G 854
G
Sbjct: 243 G 243
>BC038104-1|AAH38104.1| 355|Homo sapiens RCBTB1 protein protein.
Length = 355
Score = 124 bits (300), Expect = 3e-28
Identities = 61/182 (33%), Positives = 97/182 (53%)
Frame = +3
Query: 309 HSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDE 488
H L + G +Y+ G+N QLG T + + + +ACG HS+A+
Sbjct: 86 HVLLSTEDGVVYAWGHNGYSQLGNGTTNQGIATVQVCTNLLIKQVVEVACGSHHSMALAA 145
Query: 489 WGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 668
G+ F+WG ++ GQ+G+ A+ K L K V+ +ACG S+A+ ++G++Y W
Sbjct: 146 DGEVFAWGYNNCGQVGSGSTANQPTPRKVTNCLHIKRVVGIACGQTSSMAVLDNGEVYGW 205
Query: 669 GANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFVLSKSGAVFGWGKNTHGX 848
G N GQ GLG N +++P +++L V + I CG HT L+ G ++ WG NT+G
Sbjct: 206 GYNGNGQLGLGNNGN-QLTPVRVAALHSVCVNQIVCGYAHTLALTDEGLLYAWGANTYGQ 264
Query: 849 LG 854
LG
Sbjct: 265 LG 266
Score = 108 bits (259), Expect = 3e-23
Identities = 64/183 (34%), Positives = 98/183 (53%), Gaps = 2/183 (1%)
Frame = +3
Query: 291 VAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQH 470
VA G HS+ L+ G +++ G N+ GQ+G + ++ + + IACG
Sbjct: 133 VACGSHHSMALAADGEVFAWGYNNCGQVGSGSTANQPTPRKVTNCLHIKRVVGIACGQTS 192
Query: 471 SLAIDEWGQPFSWGSDSMGQLGNNLGAHA-QDKPKFVKGLATKNVIQVACGAYHSVALTN 647
S+A+ + G+ + WG + GQLG LG + Q P V L + V Q+ CG H++ALT+
Sbjct: 193 SMAVLDNGEVYGWGYNGNGQLG--LGNNGNQLTPVRVAALHSVCVNQIVCGYAHTLALTD 250
Query: 648 SGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFVL-SKSGAVFG 824
G LY+WGAN+YGQ G G N +SP HI + + AC + HT ++ G V+
Sbjct: 251 EGLLYAWGANTYGQLGTGN-KNNLLSPAHIMVEKERVVEIAACHSAHTSAAKTQGGHVYM 309
Query: 825 WGK 833
WG+
Sbjct: 310 WGQ 312
Score = 43.2 bits (97), Expect = 0.001
Identities = 25/78 (32%), Positives = 39/78 (50%), Gaps = 1/78 (1%)
Frame = +3
Query: 282 IQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACG 461
+ + G H+L L++ G LY+ G N GQLG + +N +PA + K+ + AC
Sbjct: 235 VNQIVCGYAHTLALTDEGLLYAWGANTYGQLGTGNK-NNLLSPAHIMVEKERVVEIAACH 293
Query: 462 LQH-SLAIDEWGQPFSWG 512
H S A + G + WG
Sbjct: 294 SAHTSAAKTQGGHVYMWG 311
>AL139321-5|CAH71047.1| 531|Homo sapiens regulator of chromosome
condensation (RCC1) and BTB (POZ) domain containing pro
protein.
Length = 531
Score = 124 bits (300), Expect = 3e-28
Identities = 65/183 (35%), Positives = 101/183 (55%), Gaps = 1/183 (0%)
Frame = +3
Query: 309 HSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVET-FKDCTISTIACGLQHSLAID 485
H L + G +Y+ G+N QLG T ++ G P V T + +ACG HS+A+
Sbjct: 86 HVLLSTEDGVVYAWGHNGYSQLGNGT-TNQGIAPVQVCTNLLIKQVVEVACGSHHSMALA 144
Query: 486 EWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYS 665
G+ F+WG ++ GQ+G+ A+ K L K V+ +ACG S+A+ ++G++Y
Sbjct: 145 ADGEVFAWGYNNCGQVGSGSTANQPTPRKVTNCLHIKRVVGIACGQTSSMAVLDNGEVYG 204
Query: 666 WGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFVLSKSGAVFGWGKNTHG 845
WG N GQ GLG N +++P +++L V + I CG HT L+ G ++ WG NT+G
Sbjct: 205 WGYNGNGQLGLGNNGN-QLTPVRVAALHSVCVNQIVCGYAHTLALTDEGLLYAWGANTYG 263
Query: 846 XLG 854
LG
Sbjct: 264 QLG 266
Score = 108 bits (260), Expect = 2e-23
Identities = 71/223 (31%), Positives = 114/223 (51%), Gaps = 3/223 (1%)
Frame = +3
Query: 174 MFCWGNATHHELCIDGSQITDLVIKPT-LSKWKESDHIQAVAAGEFHSLYLSNSGHLYSC 350
++ WG+ + +L G+ T+ I P + + VA G HS+ L+ G +++
Sbjct: 96 VYAWGHNGYSQL---GNGTTNQGIAPVQVCTNLLIKQVVEVACGSHHSMALAADGEVFAW 152
Query: 351 GNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQ 530
G N+ GQ+G + ++ + + IACG S+A+ + G+ + WG + GQ
Sbjct: 153 GYNNCGQVGSGSTANQPTPRKVTNCLHIKRVVGIACGQTSSMAVLDNGEVYGWGYNGNGQ 212
Query: 531 LGNNLGAHA-QDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTI 707
LG LG + Q P V L + V Q+ CG H++ALT+ G LY+WGAN+YGQ G G
Sbjct: 213 LG--LGNNGNQLTPVRVAALHSVCVNQIVCGYAHTLALTDEGLLYAWGANTYGQLGTGN- 269
Query: 708 SNKEMSPQHISSLIGVPIALIACGNNHTFVL-SKSGAVFGWGK 833
N +SP HI + + AC + HT ++ G V+ WG+
Sbjct: 270 KNNLLSPAHIMVEKERVVEIAACHSAHTSAAKTQGGHVYMWGQ 312
>AK096654-1|BAC04833.1| 531|Homo sapiens protein ( Homo sapiens
cDNA FLJ39335 fis, clone OCBBF2017398, moderately
similar to Homo sapiens RCC1-like G exchanging factor
RLG mRNA. ).
Length = 531
Score = 124 bits (300), Expect = 3e-28
Identities = 65/183 (35%), Positives = 101/183 (55%), Gaps = 1/183 (0%)
Frame = +3
Query: 309 HSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVET-FKDCTISTIACGLQHSLAID 485
H L + G +Y+ G+N QLG T ++ G P V T + +ACG HS+A+
Sbjct: 86 HVLLSTEDGVVYAWGHNGYSQLGNGT-TNQGIAPVQVCTNLLIKQVVEVACGSHHSMALA 144
Query: 486 EWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYS 665
G+ F+WG ++ GQ+G+ A+ K L K V+ +ACG S+A+ ++G++Y
Sbjct: 145 ADGEVFAWGYNNCGQVGSGSTANQPTPRKVTNCLHIKRVVGIACGQTSSMAVLDNGEVYG 204
Query: 666 WGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFVLSKSGAVFGWGKNTHG 845
WG N GQ GLG N +++P +++L V + I CG HT L+ G ++ WG NT+G
Sbjct: 205 WGYNGNGQLGLGNNGN-QLTPVRVAALHSVCVNQIVCGYAHTLALTDEGLLYAWGANTYG 263
Query: 846 XLG 854
LG
Sbjct: 264 QLG 266
Score = 108 bits (260), Expect = 2e-23
Identities = 71/223 (31%), Positives = 114/223 (51%), Gaps = 3/223 (1%)
Frame = +3
Query: 174 MFCWGNATHHELCIDGSQITDLVIKPT-LSKWKESDHIQAVAAGEFHSLYLSNSGHLYSC 350
++ WG+ + +L G+ T+ I P + + VA G HS+ L+ G +++
Sbjct: 96 VYAWGHNGYSQL---GNGTTNQGIAPVQVCTNLLIKQVVEVACGSHHSMALAADGEVFAW 152
Query: 351 GNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQ 530
G N+ GQ+G + ++ + + IACG S+A+ + G+ + WG + GQ
Sbjct: 153 GYNNCGQVGSGSTANQPTPRKVTNCLHIKRVVGIACGQTSSMAVLDNGEVYGWGYNGNGQ 212
Query: 531 LGNNLGAHA-QDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTI 707
LG LG + Q P V L + V Q+ CG H++ALT+ G LY+WGAN+YGQ G G
Sbjct: 213 LG--LGNNGNQLTPVRVAALHSVCVNQIVCGYAHTLALTDEGLLYAWGANTYGQLGTGN- 269
Query: 708 SNKEMSPQHISSLIGVPIALIACGNNHTFVL-SKSGAVFGWGK 833
N +SP HI + + AC + HT ++ G V+ WG+
Sbjct: 270 KNNLLSPAHIMVEKERVVEIAACHSAHTSAAKTQGGHVYMWGQ 312
>AJ319660-1|CAC40027.1| 531|Homo sapiens guanine nucleotide
exchange factor protein.
Length = 531
Score = 124 bits (300), Expect = 3e-28
Identities = 65/183 (35%), Positives = 101/183 (55%), Gaps = 1/183 (0%)
Frame = +3
Query: 309 HSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVET-FKDCTISTIACGLQHSLAID 485
H L + G +Y+ G+N QLG T ++ G P V T + +ACG HS+A+
Sbjct: 86 HVLLSTEDGVVYAWGHNGYSQLGNGT-TNQGIAPVQVCTNLLIKQVVEVACGSHHSMALA 144
Query: 486 EWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYS 665
G+ F+WG ++ GQ+G+ A+ K L K V+ +ACG S+A+ ++G++Y
Sbjct: 145 ADGEVFAWGYNNCGQVGSGSTANQPTPRKVTNCLHIKRVVGIACGQTSSMAVLDNGEVYG 204
Query: 666 WGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFVLSKSGAVFGWGKNTHG 845
WG N GQ GLG N +++P +++L V + I CG HT L+ G ++ WG NT+G
Sbjct: 205 WGYNGNGQLGLGNNGN-QLTPVRVAALHSVCVNQIVCGYAHTLALTDEGLLYAWGANTYG 263
Query: 846 XLG 854
LG
Sbjct: 264 QLG 266
Score = 108 bits (260), Expect = 2e-23
Identities = 71/223 (31%), Positives = 114/223 (51%), Gaps = 3/223 (1%)
Frame = +3
Query: 174 MFCWGNATHHELCIDGSQITDLVIKPT-LSKWKESDHIQAVAAGEFHSLYLSNSGHLYSC 350
++ WG+ + +L G+ T+ I P + + VA G HS+ L+ G +++
Sbjct: 96 VYAWGHNGYSQL---GNGTTNQGIAPVQVCTNLLIKQVVEVACGSHHSMALAADGEVFAW 152
Query: 351 GNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQ 530
G N+ GQ+G + ++ + + IACG S+A+ + G+ + WG + GQ
Sbjct: 153 GYNNCGQVGSGSTANQPTPRKVTNCLHIKRVVGIACGQTSSMAVLDNGEVYGWGYNGNGQ 212
Query: 531 LGNNLGAHA-QDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTI 707
LG LG + Q P V L + V Q+ CG H++ALT+ G LY+WGAN+YGQ G G
Sbjct: 213 LG--LGNNGNQLTPVRVAALHSVCVNQIVCGYAHTLALTDEGLLYAWGANTYGQLGTGN- 269
Query: 708 SNKEMSPQHISSLIGVPIALIACGNNHTFVL-SKSGAVFGWGK 833
N +SP HI + + AC + HT ++ G V+ WG+
Sbjct: 270 KNNLLSPAHIMVEKERVVEIAACHSAHTSAAKTQGGHVYMWGQ 312
>AF334406-1|AAK38372.1| 531|Homo sapiens CLLL7 protein protein.
Length = 531
Score = 124 bits (300), Expect = 3e-28
Identities = 65/183 (35%), Positives = 101/183 (55%), Gaps = 1/183 (0%)
Frame = +3
Query: 309 HSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVET-FKDCTISTIACGLQHSLAID 485
H L + G +Y+ G+N QLG T ++ G P V T + +ACG HS+A+
Sbjct: 86 HVLLSTEDGVVYAWGHNGYSQLGNGT-TNQGIAPVQVCTNLLIKQVVEVACGSHHSMALA 144
Query: 486 EWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYS 665
G+ F+WG ++ GQ+G+ A+ K L K V+ +ACG S+A+ ++G++Y
Sbjct: 145 ADGEVFAWGYNNCGQVGSGSTANQPTPRKVTNCLHIKRVVGIACGQTSSMAVLDNGEVYG 204
Query: 666 WGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFVLSKSGAVFGWGKNTHG 845
WG N GQ GLG N +++P +++L V + I CG HT L+ G ++ WG NT+G
Sbjct: 205 WGYNGNGQLGLGNNGN-QLTPVRVAALHSVCVNQIVCGYAHTLALTDEGLLYAWGANTYG 263
Query: 846 XLG 854
LG
Sbjct: 264 QLG 266
Score = 108 bits (260), Expect = 2e-23
Identities = 71/223 (31%), Positives = 114/223 (51%), Gaps = 3/223 (1%)
Frame = +3
Query: 174 MFCWGNATHHELCIDGSQITDLVIKPT-LSKWKESDHIQAVAAGEFHSLYLSNSGHLYSC 350
++ WG+ + +L G+ T+ I P + + VA G HS+ L+ G +++
Sbjct: 96 VYAWGHNGYSQL---GNGTTNQGIAPVQVCTNLLIKQVVEVACGSHHSMALAADGEVFAW 152
Query: 351 GNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQ 530
G N+ GQ+G + ++ + + IACG S+A+ + G+ + WG + GQ
Sbjct: 153 GYNNCGQVGSGSTANQPTPRKVTNCLHIKRVVGIACGQTSSMAVLDNGEVYGWGYNGNGQ 212
Query: 531 LGNNLGAHA-QDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTI 707
LG LG + Q P V L + V Q+ CG H++ALT+ G LY+WGAN+YGQ G G
Sbjct: 213 LG--LGNNGNQLTPVRVAALHSVCVNQIVCGYAHTLALTDEGLLYAWGANTYGQLGTGN- 269
Query: 708 SNKEMSPQHISSLIGVPIALIACGNNHTFVL-SKSGAVFGWGK 833
N +SP HI + + AC + HT ++ G V+ WG+
Sbjct: 270 KNNLLSPAHIMVEKERVVEIAACHSAHTSAAKTQGGHVYMWGQ 312
>AF224249-1|AAO27475.1| 328|Homo sapiens HERC2 protein.
Length = 328
Score = 122 bits (294), Expect = 2e-27
Identities = 75/230 (32%), Positives = 116/230 (50%), Gaps = 2/230 (0%)
Frame = +3
Query: 171 KMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSC 350
K+F WG +L D KP L + ++ I+ +A G HS L++SG LY+
Sbjct: 105 KVFWWGEGDDGKLGHFSRMNCD---KPRLIEALKTKRIRDIACGSSHSAALTSSGELYTW 161
Query: 351 GNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQ--HSLAIDEWGQPFSWGSDSM 524
G + G+LG + K P +V+ + +ACG + +LA+ + G FSWG
Sbjct: 162 GLGEYGRLGHGDNTTQLK-PKMVKVLLGHRVIQVACGSRDAQTLALTDEGLVFSWGDGDF 220
Query: 525 GQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGT 704
G+LG G+ + P+ ++ L + V Q+ CGA S+ALT SG +++WG Y + G G+
Sbjct: 221 GKLGRG-GSEGCNIPQNIERLNGQGVCQIECGAQFSLALTKSGVVWTWGKGDYFRLGHGS 279
Query: 705 ISNKEMSPQHISSLIGVPIALIACGNNHTFVLSKSGAVFGWGKNTHGXLG 854
+ PQ + L G I +A G H ++ SG V+ WG N HG G
Sbjct: 280 DVHVR-KPQVVEGLRGKKIVHVAVGALHCLAVTDSGQVYAWGDNDHGQQG 328
Score = 120 bits (288), Expect = 9e-27
Identities = 65/206 (31%), Positives = 105/206 (50%), Gaps = 4/206 (1%)
Frame = +3
Query: 249 PTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETF 428
P+ S+ + ++ VA G ++ G +Y+CG G+LG S P +
Sbjct: 21 PSFSETLSALNVVQVAGGSKSLFAVTVEGKVYACGEATNGRLGLGISSGTVPIPRQITAL 80
Query: 429 KDCTISTIAC--GLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNV 602
+ +A G +H+ A+ G+ F WG G+LG+ + DKP+ ++ L TK +
Sbjct: 81 SSYVVKKVAVHSGGRHATALTVDGKVFWWGEGDDGKLGHFSRMNC-DKPRLIEALKTKRI 139
Query: 603 IQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGN 782
+ACG+ HS ALT+SG+LY+WG YG+ G G + ++ P+ + L+G + +ACG+
Sbjct: 140 RDIACGSSHSAALTSSGELYTWGLGEYGRLGHGD-NTTQLKPKMVKVLLGHRVIQVACGS 198
Query: 783 N--HTFVLSKSGAVFGWGKNTHGXLG 854
T L+ G VF WG G LG
Sbjct: 199 RDAQTLALTDEGLVFSWGDGDFGKLG 224
Score = 101 bits (242), Expect = 3e-21
Identities = 63/188 (33%), Positives = 99/188 (52%), Gaps = 2/188 (1%)
Frame = +3
Query: 138 SSY*KKLQNYKKMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAG--EFH 311
SS+ L + +++ WG + L G T L KP + K + VA G +
Sbjct: 146 SSHSAALTSSGELYTWGLGEYGRLG-HGDNTTQL--KPKMVKVLLGHRVIQVACGSRDAQ 202
Query: 312 SLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEW 491
+L L++ G ++S G+ D G+LGR S+ P +E + I CG Q SLA+ +
Sbjct: 203 TLALTDEGLVFSWGDGDFGKLGRGG-SEGCNIPQNIERLNGQGVCQIECGAQFSLALTKS 261
Query: 492 GQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWG 671
G ++WG +LG+ H + KP+ V+GL K ++ VA GA H +A+T+SG +Y+WG
Sbjct: 262 GVVWTWGKGDYFRLGHGSDVHVR-KPQVVEGLRGKKIVHVAVGALHCLAVTDSGQVYAWG 320
Query: 672 ANSYGQCG 695
N +GQ G
Sbjct: 321 DNDHGQQG 328
>AB046813-1|BAB13419.1| 953|Homo sapiens KIAA1593 protein protein.
Length = 953
Score = 122 bits (294), Expect = 2e-27
Identities = 64/192 (33%), Positives = 102/192 (53%), Gaps = 1/192 (0%)
Frame = +3
Query: 282 IQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACG 461
I VA G +HSL LS + ++ G N GQLG T+ +P L+++ +A G
Sbjct: 35 IVQVACGYYHSLALSKASEVFCWGQNKYGQLGLGTDCKKQTSPQLLKSLLGIPFMQVAAG 94
Query: 462 LQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVAL 641
HS + G F WG + GQLG N + + P +K L ++ ++ + CG H+ AL
Sbjct: 95 GAHSFVLTLSGAIFGWGRNKFGQLGLN-DENDRYVPNLLKSLRSQKIVYICCGEDHTAAL 153
Query: 642 TNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFV-LSKSGAV 818
T G ++++GA YGQ G + S+ E++P+ + L+G + IACG HT + SG +
Sbjct: 154 TKEGGVFTFGAGGYGQLGHNSTSH-EINPRKVFELMGSIVTEIACGRQHTSAFVPSSGRI 212
Query: 819 FGWGKNTHGXLG 854
+ +G +G LG
Sbjct: 213 YSFGLGGNGQLG 224
Score = 115 bits (276), Expect = 3e-25
Identities = 47/93 (50%), Positives = 66/93 (70%)
Frame = +3
Query: 576 VKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGV 755
+K L+ ++QVACG YHS+AL+ + +++ WG N YGQ GLGT K+ SPQ + SL+G+
Sbjct: 27 IKSLSDIQIVQVACGYYHSLALSKASEVFCWGQNKYGQLGLGTDCKKQTSPQLLKSLLGI 86
Query: 756 PIALIACGNNHTFVLSKSGAVFGWGKNTHGXLG 854
P +A G H+FVL+ SGA+FGWG+N G LG
Sbjct: 87 PFMQVAAGGAHSFVLTLSGAIFGWGRNKFGQLG 119
Score = 112 bits (269), Expect = 2e-24
Identities = 56/146 (38%), Positives = 75/146 (51%)
Frame = +3
Query: 417 VETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATK 596
+++ D I +ACG HSLA+ + + F WG + GQLG Q P+ +K L
Sbjct: 27 IKSLSDIQIVQVACGYYHSLALSKASEVFCWGQNKYGQLGLGTDCKKQTSPQLLKSLLGI 86
Query: 597 NVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIAC 776
+QVA G HS LT SG ++ WG N +GQ GL N P + SL I I C
Sbjct: 87 PFMQVAAGGAHSFVLTLSGAIFGWGRNKFGQLGLND-ENDRYVPNLLKSLRSQKIVYICC 145
Query: 777 GNNHTFVLSKSGAVFGWGKNTHGXLG 854
G +HT L+K G VF +G +G LG
Sbjct: 146 GEDHTAALTKEGGVFTFGAGGYGQLG 171
Score = 100 bits (240), Expect = 6e-21
Identities = 64/189 (33%), Positives = 97/189 (51%), Gaps = 1/189 (0%)
Frame = +3
Query: 156 LQNYKKMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSG 335
L ++FCWG + +L + G+ P L K VAAG HS L+ SG
Sbjct: 48 LSKASEVFCWGQNKYGQLGL-GTDCKKQT-SPQLLKSLLGIPFMQVAAGGAHSFVLTLSG 105
Query: 336 HLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGS 515
++ G N GQLG E+D P L+++ + I I CG H+ A+ + G F++G+
Sbjct: 106 AIFGWGRNKFGQLGLNDENDRYV-PNLLKSLRSQKIVYICCGEDHTAALTKEGGVFTFGA 164
Query: 516 DSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALT-NSGDLYSWGANSYGQC 692
GQLG+N +H + P+ V L V ++ACG H+ A +SG +YS+G GQ
Sbjct: 165 GGYGQLGHNSTSH-EINPRKVFELMGSIVTEIACGRQHTSAFVPSSGRIYSFGLGGNGQL 223
Query: 693 GLGTISNKE 719
G G+ SN++
Sbjct: 224 GTGSTSNRK 232
Score = 45.2 bits (102), Expect = 3e-04
Identities = 19/42 (45%), Positives = 27/42 (64%)
Frame = +3
Query: 729 QHISSLIGVPIALIACGNNHTFVLSKSGAVFGWGKNTHGXLG 854
++I SL + I +ACG H+ LSK+ VF WG+N +G LG
Sbjct: 25 RNIKSLSDIQIVQVACGYYHSLALSKASEVFCWGQNKYGQLG 66
>AF225407-1|AAO27483.1| 409|Homo sapiens HERC2 protein.
Length = 409
Score = 115 bits (277), Expect = 2e-25
Identities = 66/214 (30%), Positives = 114/214 (53%), Gaps = 2/214 (0%)
Frame = +3
Query: 174 MFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVA--AGEFHSLYLSNSGHLYS 347
++ WG + L G ++ +KP L + + + +A +G+ +L L++ ++S
Sbjct: 16 LYTWGKGRYGRL---GHSDSEDQLKPKLVEALQGHRVVDIACGSGDAQTLCLTDDDTVWS 72
Query: 348 CGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMG 527
G+ D G+LGR SD K P +++ + + CG Q S+A+ + G ++WG
Sbjct: 73 WGDGDYGKLGRGG-SDGCKVPMKIDSLTGLGVVKVECGSQFSVALTKSGAVYTWGKGDYH 131
Query: 528 QLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTI 707
+LG+ H + +P+ V+GL K VI +A G+ H V T G++Y+WG N GQ G GT
Sbjct: 132 RLGHGSDDHVR-RPRQVQGLQGKKVIAIATGSLHCVCCTEDGEVYTWGDNDEGQLGDGT- 189
Query: 708 SNKEMSPQHISSLIGVPIALIACGNNHTFVLSKS 809
+N P+ +++L G + +ACG+ HT S S
Sbjct: 190 TNAIQRPRLVAALQGKKVNRVACGSAHTLAWSTS 223
Score = 109 bits (261), Expect = 2e-23
Identities = 64/189 (33%), Positives = 93/189 (49%), Gaps = 2/189 (1%)
Frame = +3
Query: 294 AAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGL--Q 467
AAG HS ++ +G LY+ G G+LG D K P LVE + + IACG
Sbjct: 1 AAGGAHSACVTAAGDLYTWGKGRYGRLGHSDSEDQLK-PKLVEALQGHRVVDIACGSGDA 59
Query: 468 HSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTN 647
+L + + +SWG G+LG G+ P + L V++V CG+ SVALT
Sbjct: 60 QTLCLTDDDTVWSWGDGDYGKLGRG-GSDGCKVPMKIDSLTGLGVVKVECGSQFSVALTK 118
Query: 648 SGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFVLSKSGAVFGW 827
SG +Y+WG Y + G G+ + P+ + L G + IA G+ H ++ G V+ W
Sbjct: 119 SGAVYTWGKGDYHRLGHGS-DDHVRRPRQVQGLQGKKVIAIATGSLHCVCCTEDGEVYTW 177
Query: 828 GKNTHGXLG 854
G N G LG
Sbjct: 178 GDNDEGQLG 186
>AL356741-1|CAH74146.1| 907|Homo sapiens hect domain and RLD 4
protein.
Length = 907
Score = 107 bits (257), Expect = 5e-23
Identities = 55/177 (31%), Positives = 93/177 (52%), Gaps = 1/177 (0%)
Frame = +3
Query: 327 NSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFS 506
++ ++ G N GQLG T+ +P L+++ +A G HS + G F
Sbjct: 4 SASEVFCWGQNKYGQLGLGTDCKKQTSPQLLKSLLGIPFMQVAAGGAHSFVLTLSGAIFG 63
Query: 507 WGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYG 686
WG + GQLG N + + P +K L ++ ++ + CG H+ ALT G ++++GA YG
Sbjct: 64 WGRNKFGQLGLN-DENDRYVPNLLKSLRSQKIVYICCGEDHTAALTKEGGVFTFGAGGYG 122
Query: 687 QCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFV-LSKSGAVFGWGKNTHGXLG 854
Q G + S+ E++P+ + L+G + IACG HT + SG ++ +G +G LG
Sbjct: 123 QLGHNSTSH-EINPRKVFELMGSIVTEIACGRQHTSAFVPSSGRIYSFGLGGNGQLG 178
Score = 100 bits (239), Expect = 8e-21
Identities = 63/188 (33%), Positives = 99/188 (52%), Gaps = 1/188 (0%)
Frame = +3
Query: 159 QNYKKMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGH 338
++ ++FCWG + +L + G+ P L K VAAG HS L+ SG
Sbjct: 3 ESASEVFCWGQNKYGQLGL-GTDCKKQT-SPQLLKSLLGIPFMQVAAGGAHSFVLTLSGA 60
Query: 339 LYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSD 518
++ G N GQLG E+D P L+++ + I I CG H+ A+ + G F++G+
Sbjct: 61 IFGWGRNKFGQLGLNDENDR-YVPNLLKSLRSQKIVYICCGEDHTAALTKEGGVFTFGAG 119
Query: 519 SMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVA-LTNSGDLYSWGANSYGQCG 695
GQLG+N +H + P+ V L V ++ACG H+ A + +SG +YS+G GQ G
Sbjct: 120 GYGQLGHNSTSH-EINPRKVFELMGSIVTEIACGRQHTSAFVPSSGRIYSFGLGGNGQLG 178
Query: 696 LGTISNKE 719
G+ SN++
Sbjct: 179 TGSTSNRK 186
>AL133551-1|CAI16031.1| 907|Homo sapiens hect domain and RLD 4
protein.
Length = 907
Score = 107 bits (257), Expect = 5e-23
Identities = 55/177 (31%), Positives = 93/177 (52%), Gaps = 1/177 (0%)
Frame = +3
Query: 327 NSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFS 506
++ ++ G N GQLG T+ +P L+++ +A G HS + G F
Sbjct: 4 SASEVFCWGQNKYGQLGLGTDCKKQTSPQLLKSLLGIPFMQVAAGGAHSFVLTLSGAIFG 63
Query: 507 WGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYG 686
WG + GQLG N + + P +K L ++ ++ + CG H+ ALT G ++++GA YG
Sbjct: 64 WGRNKFGQLGLN-DENDRYVPNLLKSLRSQKIVYICCGEDHTAALTKEGGVFTFGAGGYG 122
Query: 687 QCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFV-LSKSGAVFGWGKNTHGXLG 854
Q G + S+ E++P+ + L+G + IACG HT + SG ++ +G +G LG
Sbjct: 123 QLGHNSTSH-EINPRKVFELMGSIVTEIACGRQHTSAFVPSSGRIYSFGLGGNGQLG 178
Score = 100 bits (239), Expect = 8e-21
Identities = 63/188 (33%), Positives = 99/188 (52%), Gaps = 1/188 (0%)
Frame = +3
Query: 159 QNYKKMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGH 338
++ ++FCWG + +L + G+ P L K VAAG HS L+ SG
Sbjct: 3 ESASEVFCWGQNKYGQLGL-GTDCKKQT-SPQLLKSLLGIPFMQVAAGGAHSFVLTLSGA 60
Query: 339 LYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSD 518
++ G N GQLG E+D P L+++ + I I CG H+ A+ + G F++G+
Sbjct: 61 IFGWGRNKFGQLGLNDENDR-YVPNLLKSLRSQKIVYICCGEDHTAALTKEGGVFTFGAG 119
Query: 519 SMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVA-LTNSGDLYSWGANSYGQCG 695
GQLG+N +H + P+ V L V ++ACG H+ A + +SG +YS+G GQ G
Sbjct: 120 GYGQLGHNSTSH-EINPRKVFELMGSIVTEIACGRQHTSAFVPSSGRIYSFGLGGNGQLG 178
Query: 696 LGTISNKE 719
G+ SN++
Sbjct: 179 TGSTSNRK 186
>X97668-1|CAA66258.1| 815|Homo sapiens XLRP3 protein.
Length = 815
Score = 106 bits (255), Expect = 9e-23
Identities = 70/198 (35%), Positives = 106/198 (53%), Gaps = 4/198 (2%)
Frame = +3
Query: 273 SDH-IQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTIST 449
S+H I+ ++AG S L+ G L+ G+N GQ+G + S N P V K +S
Sbjct: 138 SEHKIKQLSAGSNTSAALTEDGRLFMWGDNSEGQIGLKNVS-NVCVPQQVTIGKP--VSW 194
Query: 450 IACGLQHSLAIDEWGQPFSWGSDSMGQLG---NNLGAHAQDKPKFVKGLATKNVIQVACG 620
I+CG HS + G+ + +G G+LG LG H P+ V + K VIQVACG
Sbjct: 195 ISCGYYHSAFVTTDGELYVFGEPENGKLGLPNQLLGNHRT--PQLVSEIPEK-VIQVACG 251
Query: 621 AYHSVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFVL 800
H+V LT + +Y++G +GQ GLGT + P+ I ++ I+ I+CG NHT ++
Sbjct: 252 GEHTVVLTENA-VYTFGLGQFGQLGLGTFLFETSEPKVIENIRDQTISYISCGENHTALI 310
Query: 801 SKSGAVFGWGKNTHGXLG 854
+ G ++ +G HG LG
Sbjct: 311 TDIGLMYTFGDGRHGKLG 328
Score = 105 bits (253), Expect = 2e-22
Identities = 66/199 (33%), Positives = 105/199 (52%), Gaps = 2/199 (1%)
Frame = +3
Query: 264 WKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTI 443
W ++D ++ G+ HS ++ + LY G+N+ GQLG ++S K P V+ K +
Sbjct: 31 WFKNDVPVHLSCGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKSAISK-PTCVKALKPEKV 89
Query: 444 STIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATK--NVIQVAC 617
ACG H+L E G ++ G ++ GQLG LG + V T + Q++
Sbjct: 90 KLAACGRNHTLVSTEGGNVYATGGNNEGQLG--LGDTEERNTFHVISFFTSEHKIKQLSA 147
Query: 618 GAYHSVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFV 797
G+ S ALT G L+ WG NS GQ GL +SN PQ ++ IG P++ I+CG H+
Sbjct: 148 GSNTSAALTEDGRLFMWGDNSEGQIGLKNVSN-VCVPQQVT--IGKPVSWISCGYYHSAF 204
Query: 798 LSKSGAVFGWGKNTHGXLG 854
++ G ++ +G+ +G LG
Sbjct: 205 VTTDGELYVFGEPENGKLG 223
Score = 99.1 bits (236), Expect = 2e-20
Identities = 67/229 (29%), Positives = 113/229 (49%), Gaps = 1/229 (0%)
Frame = +3
Query: 171 KMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSC 350
K++ +G+ +L + GS+ + KPT K + + ++ A G H+L + G++Y+
Sbjct: 55 KLYMFGSNNWGQLGL-GSK--SAISKPTCVKALKPEKVKLAACGRNHTLVSTEGGNVYAT 111
Query: 351 GNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQ 530
G N+ GQLG + + + I ++ G S A+ E G+ F WG +S GQ
Sbjct: 112 GGNNEGQLGLGDTEERNTFHVISFFTSEHKIKQLSAGSNTSAALTEDGRLFMWGDNSEGQ 171
Query: 531 LGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGL-GTI 707
+G ++ + G K V ++CG YHS +T G+LY +G G+ GL +
Sbjct: 172 IGLKNVSNVCVPQQVTIG---KPVSWISCGYYHSAFVTTDGELYVFGEPENGKLGLPNQL 228
Query: 708 SNKEMSPQHISSLIGVPIALIACGNNHTFVLSKSGAVFGWGKNTHGXLG 854
+PQ +S I + +ACG HT VL+++ AV+ +G G LG
Sbjct: 229 LGNHRTPQLVSE-IPEKVIQVACGGEHTVVLTEN-AVYTFGLGQFGQLG 275
Score = 88.6 bits (210), Expect = 3e-17
Identities = 50/213 (23%), Positives = 106/213 (49%), Gaps = 2/213 (0%)
Frame = +3
Query: 171 KMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSC 350
++F WG+ + ++ + ++++ + ++ K + ++ G +HS +++ G LY
Sbjct: 160 RLFMWGDNSEGQIGL--KNVSNVCVPQQVTIGKP---VSWISCGYYHSAFVTTDGELYVF 214
Query: 351 GNNDVGQLGRQTES-DNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMG 527
G + G+LG + N + P LV + I +ACG +H++ + E +++G G
Sbjct: 215 GEPENGKLGLPNQLLGNHRTPQLVSEIPEKVIQ-VACGGEHTVVLTE-NAVYTFGLGQFG 272
Query: 528 QLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTI 707
QLG +PK ++ + + + ++CG H+ +T+ G +Y++G +G+ GLG
Sbjct: 273 QLGLGTFLFETSEPKVIENIRDQTISYISCGENHTALITDIGLMYTFGDGRHGKLGLGLE 332
Query: 708 S-NKEMSPQHISSLIGVPIALIACGNNHTFVLS 803
+ P S+ + + L+ACG H V +
Sbjct: 333 NFTNHFIPTLCSNFLRFIVKLVACGGCHMVVFA 365
>U57629-1|AAC50481.1| 815|Homo sapiens retinitis pigmentosa GTPase
regulator protein.
Length = 815
Score = 106 bits (255), Expect = 9e-23
Identities = 70/198 (35%), Positives = 106/198 (53%), Gaps = 4/198 (2%)
Frame = +3
Query: 273 SDH-IQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTIST 449
S+H I+ ++AG S L+ G L+ G+N GQ+G + S N P V K +S
Sbjct: 138 SEHKIKQLSAGSNTSAALTEDGRLFMWGDNSEGQIGLKNVS-NVCVPQQVTIGKP--VSW 194
Query: 450 IACGLQHSLAIDEWGQPFSWGSDSMGQLG---NNLGAHAQDKPKFVKGLATKNVIQVACG 620
I+CG HS + G+ + +G G+LG LG H P+ V + K VIQVACG
Sbjct: 195 ISCGYYHSAFVTTDGELYVFGEPENGKLGLPNQLLGNHRT--PQLVSEIPEK-VIQVACG 251
Query: 621 AYHSVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFVL 800
H+V LT + +Y++G +GQ GLGT + P+ I ++ I+ I+CG NHT ++
Sbjct: 252 GEHTVVLTENA-VYTFGLGQFGQLGLGTFLFETSEPKVIENIRDQTISYISCGENHTALI 310
Query: 801 SKSGAVFGWGKNTHGXLG 854
+ G ++ +G HG LG
Sbjct: 311 TDIGLMYTFGDGRHGKLG 328
Score = 105 bits (253), Expect = 2e-22
Identities = 66/199 (33%), Positives = 105/199 (52%), Gaps = 2/199 (1%)
Frame = +3
Query: 264 WKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTI 443
W ++D ++ G+ HS ++ + LY G+N+ GQLG ++S K P V+ K +
Sbjct: 31 WFKNDVPVHLSCGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKSAISK-PTCVKALKPEKV 89
Query: 444 STIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATK--NVIQVAC 617
ACG H+L E G ++ G ++ GQLG LG + V T + Q++
Sbjct: 90 KLAACGRNHTLVSTEGGNVYATGGNNEGQLG--LGDTEERNTFHVISFFTSEHKIKQLSA 147
Query: 618 GAYHSVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFV 797
G+ S ALT G L+ WG NS GQ GL +SN PQ ++ IG P++ I+CG H+
Sbjct: 148 GSNTSAALTEDGRLFMWGDNSEGQIGLKNVSN-VCVPQQVT--IGKPVSWISCGYYHSAF 204
Query: 798 LSKSGAVFGWGKNTHGXLG 854
++ G ++ +G+ +G LG
Sbjct: 205 VTTDGELYVFGEPENGKLG 223
Score = 99.1 bits (236), Expect = 2e-20
Identities = 67/229 (29%), Positives = 113/229 (49%), Gaps = 1/229 (0%)
Frame = +3
Query: 171 KMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSC 350
K++ +G+ +L + GS+ + KPT K + + ++ A G H+L + G++Y+
Sbjct: 55 KLYMFGSNNWGQLGL-GSK--SAISKPTCVKALKPEKVKLAACGRNHTLVSTEGGNVYAT 111
Query: 351 GNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQ 530
G N+ GQLG + + + I ++ G S A+ E G+ F WG +S GQ
Sbjct: 112 GGNNEGQLGLGDTEERNTFHVISFFTSEHKIKQLSAGSNTSAALTEDGRLFMWGDNSEGQ 171
Query: 531 LGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGL-GTI 707
+G ++ + G K V ++CG YHS +T G+LY +G G+ GL +
Sbjct: 172 IGLKNVSNVCVPQQVTIG---KPVSWISCGYYHSAFVTTDGELYVFGEPENGKLGLPNQL 228
Query: 708 SNKEMSPQHISSLIGVPIALIACGNNHTFVLSKSGAVFGWGKNTHGXLG 854
+PQ +S I + +ACG HT VL+++ AV+ +G G LG
Sbjct: 229 LGNHRTPQLVSE-IPEKVIQVACGGEHTVVLTEN-AVYTFGLGQFGQLG 275
Score = 88.6 bits (210), Expect = 3e-17
Identities = 50/213 (23%), Positives = 106/213 (49%), Gaps = 2/213 (0%)
Frame = +3
Query: 171 KMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSC 350
++F WG+ + ++ + ++++ + ++ K + ++ G +HS +++ G LY
Sbjct: 160 RLFMWGDNSEGQIGL--KNVSNVCVPQQVTIGKP---VSWISCGYYHSAFVTTDGELYVF 214
Query: 351 GNNDVGQLGRQTES-DNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMG 527
G + G+LG + N + P LV + I +ACG +H++ + E +++G G
Sbjct: 215 GEPENGKLGLPNQLLGNHRTPQLVSEIPEKVIQ-VACGGEHTVVLTE-NAVYTFGLGQFG 272
Query: 528 QLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTI 707
QLG +PK ++ + + + ++CG H+ +T+ G +Y++G +G+ GLG
Sbjct: 273 QLGLGTFLFETSEPKVIENIRDQTISYISCGENHTALITDIGLMYTFGDGRHGKLGLGLE 332
Query: 708 S-NKEMSPQHISSLIGVPIALIACGNNHTFVLS 803
+ P S+ + + L+ACG H V +
Sbjct: 333 NFTNHFIPTLCSNFLRFIVKLVACGGCHMVVFA 365
>BC031624-1|AAH31624.1| 480|Homo sapiens RPGR protein protein.
Length = 480
Score = 106 bits (255), Expect = 9e-23
Identities = 70/198 (35%), Positives = 106/198 (53%), Gaps = 4/198 (2%)
Frame = +3
Query: 273 SDH-IQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTIST 449
S+H I+ ++AG S L+ G L+ G+N GQ+G + S N P V K +S
Sbjct: 138 SEHKIKQLSAGSNTSAALTEDGRLFMWGDNSEGQIGLKNVS-NVCVPQQVTIGKP--VSW 194
Query: 450 IACGLQHSLAIDEWGQPFSWGSDSMGQLG---NNLGAHAQDKPKFVKGLATKNVIQVACG 620
I+CG HS + G+ + +G G+LG LG H P+ V + K VIQVACG
Sbjct: 195 ISCGYYHSAFVTTDGELYVFGEPENGKLGLPNQLLGNHRT--PQLVSEIPEK-VIQVACG 251
Query: 621 AYHSVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFVL 800
H+V LT + +Y++G +GQ GLGT + P+ I ++ I+ I+CG NHT ++
Sbjct: 252 GEHTVVLTENA-VYTFGLGQFGQLGLGTFLFETSEPKVIENIRDQTISYISCGENHTALI 310
Query: 801 SKSGAVFGWGKNTHGXLG 854
+ G ++ +G HG LG
Sbjct: 311 TDIGLMYTFGDGRHGKLG 328
Score = 105 bits (253), Expect = 2e-22
Identities = 66/199 (33%), Positives = 105/199 (52%), Gaps = 2/199 (1%)
Frame = +3
Query: 264 WKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTI 443
W ++D ++ G+ HS ++ + LY G+N+ GQLG ++S K P V+ K +
Sbjct: 31 WFKNDVPVHLSCGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKSAISK-PTCVKALKPEKV 89
Query: 444 STIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATK--NVIQVAC 617
ACG H+L E G ++ G ++ GQLG LG + V T + Q++
Sbjct: 90 KLAACGRNHTLVSTEGGNVYATGGNNEGQLG--LGDTEERNTFHVISFFTSEHKIKQLSA 147
Query: 618 GAYHSVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFV 797
G+ S ALT G L+ WG NS GQ GL +SN PQ ++ IG P++ I+CG H+
Sbjct: 148 GSNTSAALTEDGRLFMWGDNSEGQIGLKNVSN-VCVPQQVT--IGKPVSWISCGYYHSAF 204
Query: 798 LSKSGAVFGWGKNTHGXLG 854
++ G ++ +G+ +G LG
Sbjct: 205 VTTDGELYVFGEPENGKLG 223
Score = 99.1 bits (236), Expect = 2e-20
Identities = 67/229 (29%), Positives = 113/229 (49%), Gaps = 1/229 (0%)
Frame = +3
Query: 171 KMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSC 350
K++ +G+ +L + GS+ + KPT K + + ++ A G H+L + G++Y+
Sbjct: 55 KLYMFGSNNWGQLGL-GSK--SAISKPTCVKALKPEKVKLAACGRNHTLVSTEGGNVYAT 111
Query: 351 GNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQ 530
G N+ GQLG + + + I ++ G S A+ E G+ F WG +S GQ
Sbjct: 112 GGNNEGQLGLGDTEERNTFHVISFFTSEHKIKQLSAGSNTSAALTEDGRLFMWGDNSEGQ 171
Query: 531 LGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGL-GTI 707
+G ++ + G K V ++CG YHS +T G+LY +G G+ GL +
Sbjct: 172 IGLKNVSNVCVPQQVTIG---KPVSWISCGYYHSAFVTTDGELYVFGEPENGKLGLPNQL 228
Query: 708 SNKEMSPQHISSLIGVPIALIACGNNHTFVLSKSGAVFGWGKNTHGXLG 854
+PQ +S I + +ACG HT VL+++ AV+ +G G LG
Sbjct: 229 LGNHRTPQLVSE-IPEKVIQVACGGEHTVVLTEN-AVYTFGLGQFGQLG 275
Score = 88.6 bits (210), Expect = 3e-17
Identities = 50/213 (23%), Positives = 106/213 (49%), Gaps = 2/213 (0%)
Frame = +3
Query: 171 KMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSC 350
++F WG+ + ++ + ++++ + ++ K + ++ G +HS +++ G LY
Sbjct: 160 RLFMWGDNSEGQIGL--KNVSNVCVPQQVTIGKP---VSWISCGYYHSAFVTTDGELYVF 214
Query: 351 GNNDVGQLGRQTES-DNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMG 527
G + G+LG + N + P LV + I +ACG +H++ + E +++G G
Sbjct: 215 GEPENGKLGLPNQLLGNHRTPQLVSEIPEKVIQ-VACGGEHTVVLTE-NAVYTFGLGQFG 272
Query: 528 QLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTI 707
QLG +PK ++ + + + ++CG H+ +T+ G +Y++G +G+ GLG
Sbjct: 273 QLGLGTFLFETSEPKVIENIRDQTISYISCGENHTALITDIGLMYTFGDGRHGKLGLGLE 332
Query: 708 S-NKEMSPQHISSLIGVPIALIACGNNHTFVLS 803
+ P S+ + + L+ACG H V +
Sbjct: 333 NFTNHFIPTLCSNFLRFIVKLVACGGCHMVVFA 365
>AL606748-2|CAI95407.1| 815|Homo sapiens retinitis pigmentosa
GTPase regulator protein.
Length = 815
Score = 106 bits (255), Expect = 9e-23
Identities = 70/198 (35%), Positives = 106/198 (53%), Gaps = 4/198 (2%)
Frame = +3
Query: 273 SDH-IQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTIST 449
S+H I+ ++AG S L+ G L+ G+N GQ+G + S N P V K +S
Sbjct: 138 SEHKIKQLSAGSNTSAALTEDGRLFMWGDNSEGQIGLKNVS-NVCVPQQVTIGKP--VSW 194
Query: 450 IACGLQHSLAIDEWGQPFSWGSDSMGQLG---NNLGAHAQDKPKFVKGLATKNVIQVACG 620
I+CG HS + G+ + +G G+LG LG H P+ V + K VIQVACG
Sbjct: 195 ISCGYYHSAFVTTDGELYVFGEPENGKLGLPNQLLGNHRT--PQLVSEIPEK-VIQVACG 251
Query: 621 AYHSVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFVL 800
H+V LT + +Y++G +GQ GLGT + P+ I ++ I+ I+CG NHT ++
Sbjct: 252 GEHTVVLTENA-VYTFGLGQFGQLGLGTFLFETSEPKVIENIRDQTISYISCGENHTALI 310
Query: 801 SKSGAVFGWGKNTHGXLG 854
+ G ++ +G HG LG
Sbjct: 311 TDIGLMYTFGDGRHGKLG 328
Score = 105 bits (253), Expect = 2e-22
Identities = 66/199 (33%), Positives = 105/199 (52%), Gaps = 2/199 (1%)
Frame = +3
Query: 264 WKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTI 443
W ++D ++ G+ HS ++ + LY G+N+ GQLG ++S K P V+ K +
Sbjct: 31 WFKNDVPVHLSCGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKSAISK-PTCVKALKPEKV 89
Query: 444 STIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATK--NVIQVAC 617
ACG H+L E G ++ G ++ GQLG LG + V T + Q++
Sbjct: 90 KLAACGRNHTLVSTEGGNVYATGGNNEGQLG--LGDTEERNTFHVISFFTSEHKIKQLSA 147
Query: 618 GAYHSVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFV 797
G+ S ALT G L+ WG NS GQ GL +SN PQ ++ IG P++ I+CG H+
Sbjct: 148 GSNTSAALTEDGRLFMWGDNSEGQIGLKNVSN-VCVPQQVT--IGKPVSWISCGYYHSAF 204
Query: 798 LSKSGAVFGWGKNTHGXLG 854
++ G ++ +G+ +G LG
Sbjct: 205 VTTDGELYVFGEPENGKLG 223
Score = 99.1 bits (236), Expect = 2e-20
Identities = 67/229 (29%), Positives = 113/229 (49%), Gaps = 1/229 (0%)
Frame = +3
Query: 171 KMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSC 350
K++ +G+ +L + GS+ + KPT K + + ++ A G H+L + G++Y+
Sbjct: 55 KLYMFGSNNWGQLGL-GSK--SAISKPTCVKALKPEKVKLAACGRNHTLVSTEGGNVYAT 111
Query: 351 GNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQ 530
G N+ GQLG + + + I ++ G S A+ E G+ F WG +S GQ
Sbjct: 112 GGNNEGQLGLGDTEERNTFHVISFFTSEHKIKQLSAGSNTSAALTEDGRLFMWGDNSEGQ 171
Query: 531 LGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGL-GTI 707
+G ++ + G K V ++CG YHS +T G+LY +G G+ GL +
Sbjct: 172 IGLKNVSNVCVPQQVTIG---KPVSWISCGYYHSAFVTTDGELYVFGEPENGKLGLPNQL 228
Query: 708 SNKEMSPQHISSLIGVPIALIACGNNHTFVLSKSGAVFGWGKNTHGXLG 854
+PQ +S I + +ACG HT VL+++ AV+ +G G LG
Sbjct: 229 LGNHRTPQLVSE-IPEKVIQVACGGEHTVVLTEN-AVYTFGLGQFGQLG 275
Score = 88.6 bits (210), Expect = 3e-17
Identities = 50/213 (23%), Positives = 106/213 (49%), Gaps = 2/213 (0%)
Frame = +3
Query: 171 KMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSC 350
++F WG+ + ++ + ++++ + ++ K + ++ G +HS +++ G LY
Sbjct: 160 RLFMWGDNSEGQIGL--KNVSNVCVPQQVTIGKP---VSWISCGYYHSAFVTTDGELYVF 214
Query: 351 GNNDVGQLGRQTES-DNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMG 527
G + G+LG + N + P LV + I +ACG +H++ + E +++G G
Sbjct: 215 GEPENGKLGLPNQLLGNHRTPQLVSEIPEKVIQ-VACGGEHTVVLTE-NAVYTFGLGQFG 272
Query: 528 QLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTI 707
QLG +PK ++ + + + ++CG H+ +T+ G +Y++G +G+ GLG
Sbjct: 273 QLGLGTFLFETSEPKVIENIRDQTISYISCGENHTALITDIGLMYTFGDGRHGKLGLGLE 332
Query: 708 S-NKEMSPQHISSLIGVPIALIACGNNHTFVLS 803
+ P S+ + + L+ACG H V +
Sbjct: 333 NFTNHFIPTLCSNFLRFIVKLVACGGCHMVVFA 365
>AK223491-1|BAD97211.1| 815|Homo sapiens retinitis pigmentosa
GTPase regulator variant protein.
Length = 815
Score = 106 bits (255), Expect = 9e-23
Identities = 70/198 (35%), Positives = 106/198 (53%), Gaps = 4/198 (2%)
Frame = +3
Query: 273 SDH-IQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTIST 449
S+H I+ ++AG S L+ G L+ G+N GQ+G + S N P V K +S
Sbjct: 138 SEHKIKQLSAGSNTSAALTEDGRLFMWGDNSEGQIGLKNVS-NVCVPQQVTIGKP--VSW 194
Query: 450 IACGLQHSLAIDEWGQPFSWGSDSMGQLG---NNLGAHAQDKPKFVKGLATKNVIQVACG 620
I+CG HS + G+ + +G G+LG LG H P+ V + K VIQVACG
Sbjct: 195 ISCGYYHSAFVTTDGELYVFGEPENGKLGLPNQLLGNHRT--PQLVSEIPEK-VIQVACG 251
Query: 621 AYHSVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFVL 800
H+V LT + +Y++G +GQ GLGT + P+ I ++ I+ I+CG NHT ++
Sbjct: 252 GEHTVVLTENA-VYTFGLGQFGQLGLGTFLFETSEPKVIENIRDQTISYISCGENHTALI 310
Query: 801 SKSGAVFGWGKNTHGXLG 854
+ G ++ +G HG LG
Sbjct: 311 TDIGLMYTFGDGRHGKLG 328
Score = 105 bits (253), Expect = 2e-22
Identities = 66/199 (33%), Positives = 105/199 (52%), Gaps = 2/199 (1%)
Frame = +3
Query: 264 WKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTI 443
W ++D ++ G+ HS ++ + LY G+N+ GQLG ++S K P V+ K +
Sbjct: 31 WFKNDVPVHLSCGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKSAISK-PTCVKALKPEKV 89
Query: 444 STIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATK--NVIQVAC 617
ACG H+L E G ++ G ++ GQLG LG + V T + Q++
Sbjct: 90 KLAACGRNHTLVSTEGGNVYATGGNNEGQLG--LGDTEERNTFHVISFFTSEHKIKQLSA 147
Query: 618 GAYHSVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFV 797
G+ S ALT G L+ WG NS GQ GL +SN PQ ++ IG P++ I+CG H+
Sbjct: 148 GSNTSAALTEDGRLFMWGDNSEGQIGLKNVSN-VCVPQQVT--IGKPVSWISCGYYHSAF 204
Query: 798 LSKSGAVFGWGKNTHGXLG 854
++ G ++ +G+ +G LG
Sbjct: 205 VTTDGELYVFGEPENGKLG 223
Score = 99.1 bits (236), Expect = 2e-20
Identities = 67/229 (29%), Positives = 113/229 (49%), Gaps = 1/229 (0%)
Frame = +3
Query: 171 KMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSC 350
K++ +G+ +L + GS+ + KPT K + + ++ A G H+L + G++Y+
Sbjct: 55 KLYMFGSNNWGQLGL-GSK--SAISKPTCVKALKPEKVKLAACGRNHTLVSTEGGNVYAT 111
Query: 351 GNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQ 530
G N+ GQLG + + + I ++ G S A+ E G+ F WG +S GQ
Sbjct: 112 GGNNEGQLGLGDTEERNTFHVISFFTSEHKIKQLSAGSNTSAALTEDGRLFMWGDNSEGQ 171
Query: 531 LGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGL-GTI 707
+G ++ + G K V ++CG YHS +T G+LY +G G+ GL +
Sbjct: 172 IGLKNVSNVCVPQQVTIG---KPVSWISCGYYHSAFVTTDGELYVFGEPENGKLGLPNQL 228
Query: 708 SNKEMSPQHISSLIGVPIALIACGNNHTFVLSKSGAVFGWGKNTHGXLG 854
+PQ +S I + +ACG HT VL+++ AV+ +G G LG
Sbjct: 229 LGNHRTPQLVSE-IPEKVIQVACGGEHTVVLTEN-AVYTFGLGQFGQLG 275
Score = 88.6 bits (210), Expect = 3e-17
Identities = 50/213 (23%), Positives = 106/213 (49%), Gaps = 2/213 (0%)
Frame = +3
Query: 171 KMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSC 350
++F WG+ + ++ + ++++ + ++ K + ++ G +HS +++ G LY
Sbjct: 160 RLFMWGDNSEGQIGL--KNVSNVCVPQQVTIGKP---VSWISCGYYHSAFVTTDGELYVF 214
Query: 351 GNNDVGQLGRQTES-DNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMG 527
G + G+LG + N + P LV + I +ACG +H++ + E +++G G
Sbjct: 215 GEPENGKLGLPNQLLGNHRTPQLVSEIPEKVIQ-VACGGEHTVVLTE-NAVYTFGLGQFG 272
Query: 528 QLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTI 707
QLG +PK ++ + + + ++CG H+ +T+ G +Y++G +G+ GLG
Sbjct: 273 QLGLGTFLFETSEPKVIENIRDQTISYISCGENHTALITDIGLMYTFGDGRHGKLGLGLE 332
Query: 708 S-NKEMSPQHISSLIGVPIALIACGNNHTFVLS 803
+ P S+ + + L+ACG H V +
Sbjct: 333 NFTNHFIPTLCSNFLRFIVKLVACGGCHMVVFA 365
>AJ238395-1|CAB54002.1| 646|Homo sapiens RPGR protein protein.
Length = 646
Score = 106 bits (255), Expect = 9e-23
Identities = 70/198 (35%), Positives = 106/198 (53%), Gaps = 4/198 (2%)
Frame = +3
Query: 273 SDH-IQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTIST 449
S+H I+ ++AG S L+ G L+ G+N GQ+G + S N P V K +S
Sbjct: 138 SEHKIKQLSAGSNTSAALTEDGRLFMWGDNSEGQIGLKNVS-NVCVPQQVTIGKP--VSW 194
Query: 450 IACGLQHSLAIDEWGQPFSWGSDSMGQLG---NNLGAHAQDKPKFVKGLATKNVIQVACG 620
I+CG HS + G+ + +G G+LG LG H P+ V + K VIQVACG
Sbjct: 195 ISCGYYHSAFVTTDGELYVFGEPENGKLGLPNQLLGNHRT--PQLVSEIPEK-VIQVACG 251
Query: 621 AYHSVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFVL 800
H+V LT + +Y++G +GQ GLGT + P+ I ++ I+ I+CG NHT ++
Sbjct: 252 GEHTVVLTENA-VYTFGLGQFGQLGLGTFLFETSEPKVIENIRDQTISYISCGENHTALI 310
Query: 801 SKSGAVFGWGKNTHGXLG 854
+ G ++ +G HG LG
Sbjct: 311 TDIGLMYTFGDGRHGKLG 328
Score = 105 bits (253), Expect = 2e-22
Identities = 66/199 (33%), Positives = 105/199 (52%), Gaps = 2/199 (1%)
Frame = +3
Query: 264 WKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTI 443
W ++D ++ G+ HS ++ + LY G+N+ GQLG ++S K P V+ K +
Sbjct: 31 WFKNDVPVHLSCGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKSAISK-PTCVKALKPEKV 89
Query: 444 STIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATK--NVIQVAC 617
ACG H+L E G ++ G ++ GQLG LG + V T + Q++
Sbjct: 90 KLAACGRNHTLVSTEGGNVYATGGNNEGQLG--LGDTEERNTFHVISFFTSEHKIKQLSA 147
Query: 618 GAYHSVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFV 797
G+ S ALT G L+ WG NS GQ GL +SN PQ ++ IG P++ I+CG H+
Sbjct: 148 GSNTSAALTEDGRLFMWGDNSEGQIGLKNVSN-VCVPQQVT--IGKPVSWISCGYYHSAF 204
Query: 798 LSKSGAVFGWGKNTHGXLG 854
++ G ++ +G+ +G LG
Sbjct: 205 VTTDGELYVFGEPENGKLG 223
Score = 99.1 bits (236), Expect = 2e-20
Identities = 67/229 (29%), Positives = 113/229 (49%), Gaps = 1/229 (0%)
Frame = +3
Query: 171 KMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSC 350
K++ +G+ +L + GS+ + KPT K + + ++ A G H+L + G++Y+
Sbjct: 55 KLYMFGSNNWGQLGL-GSK--SAISKPTCVKALKPEKVKLAACGRNHTLVSTEGGNVYAT 111
Query: 351 GNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQ 530
G N+ GQLG + + + I ++ G S A+ E G+ F WG +S GQ
Sbjct: 112 GGNNEGQLGLGDTEERNTFHVISFFTSEHKIKQLSAGSNTSAALTEDGRLFMWGDNSEGQ 171
Query: 531 LGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGL-GTI 707
+G ++ + G K V ++CG YHS +T G+LY +G G+ GL +
Sbjct: 172 IGLKNVSNVCVPQQVTIG---KPVSWISCGYYHSAFVTTDGELYVFGEPENGKLGLPNQL 228
Query: 708 SNKEMSPQHISSLIGVPIALIACGNNHTFVLSKSGAVFGWGKNTHGXLG 854
+PQ +S I + +ACG HT VL+++ AV+ +G G LG
Sbjct: 229 LGNHRTPQLVSE-IPEKVIQVACGGEHTVVLTEN-AVYTFGLGQFGQLG 275
Score = 88.6 bits (210), Expect = 3e-17
Identities = 50/213 (23%), Positives = 106/213 (49%), Gaps = 2/213 (0%)
Frame = +3
Query: 171 KMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSC 350
++F WG+ + ++ + ++++ + ++ K + ++ G +HS +++ G LY
Sbjct: 160 RLFMWGDNSEGQIGL--KNVSNVCVPQQVTIGKP---VSWISCGYYHSAFVTTDGELYVF 214
Query: 351 GNNDVGQLGRQTES-DNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMG 527
G + G+LG + N + P LV + I +ACG +H++ + E +++G G
Sbjct: 215 GEPENGKLGLPNQLLGNHRTPQLVSEIPEKVIQ-VACGGEHTVVLTE-NAVYTFGLGQFG 272
Query: 528 QLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTI 707
QLG +PK ++ + + + ++CG H+ +T+ G +Y++G +G+ GLG
Sbjct: 273 QLGLGTFLFETSEPKVIENIRDQTISYISCGENHTALITDIGLMYTFGDGRHGKLGLGLE 332
Query: 708 S-NKEMSPQHISSLIGVPIALIACGNNHTFVLS 803
+ P S+ + + L+ACG H V +
Sbjct: 333 NFTNHFIPTLCSNFLRFIVKLVACGGCHMVVFA 365
>AJ318463-1|CAC86116.1| 815|Homo sapiens retinitis pigmentosa
GTPase regulator protein.
Length = 815
Score = 105 bits (252), Expect = 2e-22
Identities = 66/199 (33%), Positives = 105/199 (52%), Gaps = 2/199 (1%)
Frame = +3
Query: 264 WKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTI 443
W ++D ++ G+ HS ++ + LY G+N+ GQLG ++S K P V+ K +
Sbjct: 31 WFKNDVPVHLSCGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKSAISK-PTCVKALKPEKV 89
Query: 444 STIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATK--NVIQVAC 617
ACG H+L E G ++ G ++ GQLG LG + V T + Q++
Sbjct: 90 KLAACGRNHTLVSTEGGNVYATGGNNEGQLG--LGDTEERNTFHVISFFTSEHKIKQLSA 147
Query: 618 GAYHSVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFV 797
G+ S ALT G L+ WG NS GQ GL +SN PQ ++ IG P++ I+CG H+
Sbjct: 148 GSNTSAALTEDGRLFMWGDNSEGQIGLKNVSN-VCVPQQVT--IGNPVSWISCGYYHSAF 204
Query: 798 LSKSGAVFGWGKNTHGXLG 854
++ G ++ +G+ +G LG
Sbjct: 205 VTTDGELYVFGEPENGKLG 223
Score = 104 bits (250), Expect = 4e-22
Identities = 69/198 (34%), Positives = 105/198 (53%), Gaps = 4/198 (2%)
Frame = +3
Query: 273 SDH-IQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTIST 449
S+H I+ ++AG S L+ G L+ G+N GQ+G + S N P V +S
Sbjct: 138 SEHKIKQLSAGSNTSAALTEDGRLFMWGDNSEGQIGLKNVS-NVCVPQQVTIGNP--VSW 194
Query: 450 IACGLQHSLAIDEWGQPFSWGSDSMGQLG---NNLGAHAQDKPKFVKGLATKNVIQVACG 620
I+CG HS + G+ + +G G+LG LG H P+ V + K VIQVACG
Sbjct: 195 ISCGYYHSAFVTTDGELYVFGEPENGKLGLPNQLLGNHRT--PQLVSEIPEK-VIQVACG 251
Query: 621 AYHSVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFVL 800
H+V LT + +Y++G +GQ GLGT + P+ I ++ I+ I+CG NHT ++
Sbjct: 252 GEHTVVLTENA-VYTFGLGQFGQLGLGTFLFETSEPKVIENIRDQTISYISCGENHTALI 310
Query: 801 SKSGAVFGWGKNTHGXLG 854
+ G ++ +G HG LG
Sbjct: 311 TDIGLMYTFGDGRHGKLG 328
Score = 97.1 bits (231), Expect = 7e-20
Identities = 66/229 (28%), Positives = 112/229 (48%), Gaps = 1/229 (0%)
Frame = +3
Query: 171 KMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSC 350
K++ +G+ +L + GS+ + KPT K + + ++ A G H+L + G++Y+
Sbjct: 55 KLYMFGSNNWGQLGL-GSK--SAISKPTCVKALKPEKVKLAACGRNHTLVSTEGGNVYAT 111
Query: 351 GNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQ 530
G N+ GQLG + + + I ++ G S A+ E G+ F WG +S GQ
Sbjct: 112 GGNNEGQLGLGDTEERNTFHVISFFTSEHKIKQLSAGSNTSAALTEDGRLFMWGDNSEGQ 171
Query: 531 LGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGL-GTI 707
+G ++ + G V ++CG YHS +T G+LY +G G+ GL +
Sbjct: 172 IGLKNVSNVCVPQQVTIG---NPVSWISCGYYHSAFVTTDGELYVFGEPENGKLGLPNQL 228
Query: 708 SNKEMSPQHISSLIGVPIALIACGNNHTFVLSKSGAVFGWGKNTHGXLG 854
+PQ +S I + +ACG HT VL+++ AV+ +G G LG
Sbjct: 229 LGNHRTPQLVSE-IPEKVIQVACGGEHTVVLTEN-AVYTFGLGQFGQLG 275
Score = 87.4 bits (207), Expect = 6e-17
Identities = 49/213 (23%), Positives = 106/213 (49%), Gaps = 2/213 (0%)
Frame = +3
Query: 171 KMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSC 350
++F WG+ + ++ + ++++ + ++ + + ++ G +HS +++ G LY
Sbjct: 160 RLFMWGDNSEGQIGL--KNVSNVCVPQQVTI---GNPVSWISCGYYHSAFVTTDGELYVF 214
Query: 351 GNNDVGQLGRQTES-DNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMG 527
G + G+LG + N + P LV + I +ACG +H++ + E +++G G
Sbjct: 215 GEPENGKLGLPNQLLGNHRTPQLVSEIPEKVIQ-VACGGEHTVVLTE-NAVYTFGLGQFG 272
Query: 528 QLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTI 707
QLG +PK ++ + + + ++CG H+ +T+ G +Y++G +G+ GLG
Sbjct: 273 QLGLGTFLFETSEPKVIENIRDQTISYISCGENHTALITDIGLMYTFGDGRHGKLGLGLE 332
Query: 708 S-NKEMSPQHISSLIGVPIALIACGNNHTFVLS 803
+ P S+ + + L+ACG H V +
Sbjct: 333 NFTNHFIPTLCSNFLRFIVKLVACGGCHMVVFA 365
>AK092403-1|BAC03879.1| 184|Homo sapiens protein ( Homo sapiens
cDNA FLJ35084 fis, clone PLACE6005482. ).
Length = 184
Score = 104 bits (250), Expect = 4e-22
Identities = 56/146 (38%), Positives = 79/146 (54%), Gaps = 2/146 (1%)
Frame = +3
Query: 423 TFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNV 602
T D I ++CG HSLA+ + Q FSWG +S GQLG +Q P+ V+ L +
Sbjct: 2 TLNDIKIIQVSCGHYHSLALSKDSQVFSWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPL 61
Query: 603 IQVACGAYHSVALTNSGDLYSWGANSYGQCGLG--TISNKEMSPQHISSLIGVPIALIAC 776
QVA G HS AL+ G + WG+NS GQ L + + P + +L + + I+C
Sbjct: 62 AQVAAGGAHSFALSLCGTSFGWGSNSAGQLALSGRNVPVQSNKPLSVGALKNLGVVYISC 121
Query: 777 GNNHTFVLSKSGAVFGWGKNTHGXLG 854
G+ HT VL++ G VF +G N G LG
Sbjct: 122 GDAHTAVLTQDGKVFTFGDNRSGQLG 147
Score = 100 bits (240), Expect = 6e-21
Identities = 57/168 (33%), Positives = 86/168 (51%), Gaps = 3/168 (1%)
Frame = +3
Query: 291 VAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQH 470
V+ G +HSL LS ++S G N GQLG E + +P V + + ++ +A G H
Sbjct: 11 VSCGHYHSLALSKDSQVFSWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAAGGAH 70
Query: 471 SLAIDEWGQPFSWGSDSMGQL---GNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVAL 641
S A+ G F WGS+S GQL G N+ + +KP V L V+ ++CG H+ L
Sbjct: 71 SFALSLCGTSFGWGSNSAGQLALSGRNVPVQS-NKPLSVGALKNLGVVYISCGDAHTAVL 129
Query: 642 TNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNN 785
T G ++++G N GQ G K PQ + + G+ ++ I CG N
Sbjct: 130 TQDGKVFTFGDNRSGQLGYSPTPEKR-GPQLVERIDGL-VSQIDCGRN 175
>AC004460-2|AAC06339.1| 371|Homo sapiens WUGSC:H_DJ1086D14.2
protein.
Length = 371
Score = 101 bits (243), Expect = 3e-21
Identities = 54/153 (35%), Positives = 84/153 (54%)
Frame = +3
Query: 333 GHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWG 512
G ++S G+ D G+LGR S+ P +E + I CG Q LA+ + G ++WG
Sbjct: 1 GLVFSWGDGDFGKLGRGG-SEGCNIPQNIERLNGQGVCQIECGAQFLLALTKSGVVWTWG 59
Query: 513 SDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQC 692
+LG+ H + KP+ V+GL K ++ VA GA H +A+ +SG +Y+WG N +GQ
Sbjct: 60 KGDYFRLGHRSDVHVR-KPQVVEGLRGKKIVHVAVGAQHCLAVMDSGQVYAWGDNDHGQQ 118
Query: 693 GLGTISNKEMSPQHISSLIGVPIALIACGNNHT 791
G GT + P + L G I +ACG++H+
Sbjct: 119 GNGT-TTVNRKPMLVQGLEGQKIMCVACGSSHS 150
Score = 79.4 bits (187), Expect = 2e-14
Identities = 44/122 (36%), Positives = 63/122 (51%), Gaps = 1/122 (0%)
Frame = +3
Query: 492 GQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWG 671
G FSWG G+LG G+ + P+ ++ L + V Q+ CGA +ALT SG +++WG
Sbjct: 1 GLVFSWGDGDFGKLGRG-GSEGCNIPQNIERLNGQGVCQIECGAQFLLALTKSGVVWTWG 59
Query: 672 ANSYGQCGLGTISNKEM-SPQHISSLIGVPIALIACGNNHTFVLSKSGAVFGWGKNTHGX 848
Y + LG S+ + PQ + L G I +A G H + SG V+ WG N HG
Sbjct: 60 KGDYFR--LGHRSDVHVRKPQVVEGLRGKKIVHVAVGAQHCLAVMDSGQVYAWGDNDHGQ 117
Query: 849 LG 854
G
Sbjct: 118 QG 119
Score = 76.2 bits (179), Expect = 1e-13
Identities = 48/157 (30%), Positives = 80/157 (50%)
Frame = +3
Query: 174 MFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCG 353
+F WG+ +L GS+ ++ P + + + G L L+ SG +++ G
Sbjct: 3 VFSWGDGDFGKLGRGGSEGCNI---PQNIERLNGQGVCQIECGAQFLLALTKSGVVWTWG 59
Query: 354 NNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQL 533
D +LG +++ + + P +VE + I +A G QH LA+ + GQ ++WG + GQ
Sbjct: 60 KGDYFRLGHRSDV-HVRKPQVVEGLRGKKIVHVAVGAQHCLAVMDSGQVYAWGDNDHGQQ 118
Query: 534 GNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALT 644
GN KP V+GL + ++ VACG+ HSVA T
Sbjct: 119 GNGTTT-VNRKPMLVQGLEGQKIMCVACGSSHSVAWT 154
>BC065375-1|AAH65375.1| 458|Homo sapiens secretion regulating
guanine nucleotide exchange factor protein.
Length = 458
Score = 101 bits (242), Expect = 3e-21
Identities = 66/234 (28%), Positives = 112/234 (47%), Gaps = 8/234 (3%)
Frame = +3
Query: 174 MFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCG 353
+F WG ++ +L + + D+++ L+ + + ++ + G HS +++ G L+ CG
Sbjct: 17 LFAWGANSYGQLGLGHKE--DVLLPQQLNDFCKPRSVRRITGGGGHSAVVTDGGDLFVCG 74
Query: 354 NNDVGQLGR-QTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQ 530
N GQLG TE P ++ C I +ACG ++ + E GQ S GS+S GQ
Sbjct: 75 LNKDGQLGLGHTEDIPYFTPC--KSLFGCPIQQVACGWDFTIMLTENGQVLSCGSNSFGQ 132
Query: 531 LGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTIS 710
LG G P+ ++ L + V+ +A G H+VA T SG ++ WG CG
Sbjct: 133 LGVPHGPRRCVVPQAIE-LHKEKVVCIAAGLRHAVAATASGIVFQWG-TGLASCGRRLCP 190
Query: 711 NKEM-------SPQHISSLIGVPIALIACGNNHTFVLSKSGAVFGWGKNTHGXL 851
+ + P ++ L + G++H+ L+ +G V+ WG N HG L
Sbjct: 191 GQTLPLFFTAKEPSRVTGLENSKAMCVLAGSDHSASLTDAGEVYVWGSNKHGQL 244
Score = 89.4 bits (212), Expect = 1e-17
Identities = 64/199 (32%), Positives = 96/199 (48%), Gaps = 8/199 (4%)
Frame = +3
Query: 282 IQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACG 461
IQ VA G ++ L+ +G + SCG+N GQLG P +E K+ + IA G
Sbjct: 103 IQQVACGWDFTIMLTENGQVLSCGSNSFGQLGVPHGPRRCVVPQAIELHKEKVVC-IAAG 161
Query: 462 LQHSLAIDEWGQPFSWGSD--SMGQL---GNNLGAHAQDK-PKFVKGLATKNVIQVACGA 623
L+H++A G F WG+ S G+ G L K P V GL + V G+
Sbjct: 162 LRHAVAATASGIVFQWGTGLASCGRRLCPGQTLPLFFTAKEPSRVTGLENSKAMCVLAGS 221
Query: 624 YHSVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISS--LIGVPIALIACGNNHTFV 797
HS +LT++G++Y WG+N +GQ L + PQ I + + I G H
Sbjct: 222 DHSASLTDAGEVYVWGSNKHGQ--LANEAAFLPVPQKIEAHCFQNEKVTAIWSGWTHLVA 279
Query: 798 LSKSGAVFGWGKNTHGXLG 854
+++G +F WG+ +G LG
Sbjct: 280 QTETGKMFTWGRADYGQLG 298
Score = 82.2 bits (194), Expect = 2e-15
Identities = 56/192 (29%), Positives = 89/192 (46%), Gaps = 15/192 (7%)
Frame = +3
Query: 270 ESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTIST 449
E+ V AG HS L+++G +Y G+N GQL + F++ ++
Sbjct: 210 ENSKAMCVLAGSDHSASLTDAGEVYVWGSNKHGQLANEAAFLPVPQKIEAHCFQNEKVTA 269
Query: 450 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNL----GAHAQDKPKFVKGLATKNVI---- 605
I G H +A E G+ F+WG GQLG L G + + F+ N +
Sbjct: 270 IWSGWTHLVAQTETGKMFTWGRADYGQLGRKLETYEGWKLEKQDSFLPCSRPPNSMPSSP 329
Query: 606 -------QVACGAYHSVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIA 764
+V+CG+ H++A+ G YSWG N +G CG GT +N +P+ + +L+
Sbjct: 330 HCLTGATEVSCGSEHNLAIIG-GVCYSWGWNEHGMCGDGTEAN-VWAPKPVQALLSSSGL 387
Query: 765 LIACGNNHTFVL 800
L+ CG H+ L
Sbjct: 388 LVGCGAGHSLAL 399
Score = 72.5 bits (170), Expect = 2e-12
Identities = 47/122 (38%), Positives = 68/122 (55%), Gaps = 4/122 (3%)
Frame = +3
Query: 501 FSWGSDSMGQLGNNLGAHAQDK--PKFVKGLAT-KNVIQVACGAYHSVALTNSGDLYSWG 671
F+WG++S GQLG LG H +D P+ + ++V ++ G HS +T+ GDL+ G
Sbjct: 18 FAWGANSYGQLG--LG-HKEDVLLPQQLNDFCKPRSVRRITGGGGHSAVVTDGGDLFVCG 74
Query: 672 ANSYGQCGLG-TISNKEMSPQHISSLIGVPIALIACGNNHTFVLSKSGAVFGWGKNTHGX 848
N GQ GLG T +P SL G PI +ACG + T +L+++G V G N+ G
Sbjct: 75 LNKDGQLGLGHTEDIPYFTP--CKSLFGCPIQQVACGWDFTIMLTENGQVLSCGSNSFGQ 132
Query: 849 LG 854
LG
Sbjct: 133 LG 134
Score = 64.1 bits (149), Expect = 6e-10
Identities = 48/185 (25%), Positives = 91/185 (49%), Gaps = 15/185 (8%)
Frame = +3
Query: 132 ANSSY*KKLQNYKKMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFH 311
A S + L + +++ WG+ H +L + + + V + + +++ + A+ +G H
Sbjct: 219 AGSDHSASLTDAGEVYVWGSNKHGQLANEAAFLP--VPQKIEAHCFQNEKVTAIWSGWTH 276
Query: 312 SLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCT---------------IS 446
+ + +G +++ G D GQLGR+ E+ G ++F C+ +
Sbjct: 277 LVAQTETGKMFTWGRADYGQLGRKLETYEGWKLEKQDSFLPCSRPPNSMPSSPHCLTGAT 336
Query: 447 TIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAY 626
++CG +H+LAI G +SWG + G G+ A+ PK V+ L + + + V CGA
Sbjct: 337 EVSCGSEHNLAI-IGGVCYSWGWNEHGMCGDGTEANVW-APKPVQALLSSSGLLVGCGAG 394
Query: 627 HSVAL 641
HS+AL
Sbjct: 395 HSLAL 399
Score = 45.6 bits (103), Expect = 2e-04
Identities = 27/76 (35%), Positives = 38/76 (50%), Gaps = 1/76 (1%)
Frame = +3
Query: 630 SVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGV-PIALIACGNNHTFVLSK 806
S A + L++WGANSYGQ GLG + PQ ++ + I G H+ V++
Sbjct: 8 SEAAPAAAALFAWGANSYGQLGLGH-KEDVLLPQQLNDFCKPRSVRRITGGGGHSAVVTD 66
Query: 807 SGAVFGWGKNTHGXLG 854
G +F G N G LG
Sbjct: 67 GGDLFVCGLNKDGQLG 82
>AJ243951-1|CAB60833.1| 288|Homo sapiens deafness locus associated
putative guanine nucleotide exchange factor protein.
Length = 288
Score = 101 bits (242), Expect = 3e-21
Identities = 66/234 (28%), Positives = 112/234 (47%), Gaps = 8/234 (3%)
Frame = +3
Query: 174 MFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCG 353
+F WG ++ +L + + D+++ L+ + + ++ + G HS +++ G L+ CG
Sbjct: 17 LFAWGANSYGQLGLGHKE--DVLLPQQLNDFCKPRSVRRITGGGGHSAVVTDGGDLFVCG 74
Query: 354 NNDVGQLGR-QTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQ 530
N GQLG TE P ++ C I +ACG ++ + E GQ S GS+S GQ
Sbjct: 75 LNKDGQLGLGHTEDIPYFTPC--KSLFGCPIQQVACGWDFTIMLTENGQVLSCGSNSFGQ 132
Query: 531 LGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTIS 710
LG G P+ ++ L + V+ +A G H+VA T SG ++ WG CG
Sbjct: 133 LGVPHGPRRCVVPQAIE-LHKEKVVCIAAGLRHAVAATASGIVFQWG-TGLASCGRRLCP 190
Query: 711 NKEM-------SPQHISSLIGVPIALIACGNNHTFVLSKSGAVFGWGKNTHGXL 851
+ + P ++ L + G++H+ L+ +G V+ WG N HG L
Sbjct: 191 GQTLPLFFTAKEPSRVTGLENSKAMCVLAGSDHSASLTDAGEVYVWGSNKHGQL 244
Score = 72.5 bits (170), Expect = 2e-12
Identities = 47/122 (38%), Positives = 68/122 (55%), Gaps = 4/122 (3%)
Frame = +3
Query: 501 FSWGSDSMGQLGNNLGAHAQDK--PKFVKGLAT-KNVIQVACGAYHSVALTNSGDLYSWG 671
F+WG++S GQLG LG H +D P+ + ++V ++ G HS +T+ GDL+ G
Sbjct: 18 FAWGANSYGQLG--LG-HKEDVLLPQQLNDFCKPRSVRRITGGGGHSAVVTDGGDLFVCG 74
Query: 672 ANSYGQCGLG-TISNKEMSPQHISSLIGVPIALIACGNNHTFVLSKSGAVFGWGKNTHGX 848
N GQ GLG T +P SL G PI +ACG + T +L+++G V G N+ G
Sbjct: 75 LNKDGQLGLGHTEDIPYFTP--CKSLFGCPIQQVACGWDFTIMLTENGQVLSCGSNSFGQ 132
Query: 849 LG 854
LG
Sbjct: 133 LG 134
Score = 45.6 bits (103), Expect = 2e-04
Identities = 27/76 (35%), Positives = 38/76 (50%), Gaps = 1/76 (1%)
Frame = +3
Query: 630 SVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGV-PIALIACGNNHTFVLSK 806
S A + L++WGANSYGQ GLG + PQ ++ + I G H+ V++
Sbjct: 8 SEAAPAAAALFAWGANSYGQLGLGH-KEDVLLPQQLNDFCKPRSVRRITGGGGHSAVVTD 66
Query: 807 SGAVFGWGKNTHGXLG 854
G +F G N G LG
Sbjct: 67 GGDLFVCGLNKDGQLG 82
Score = 36.3 bits (80), Expect = 0.14
Identities = 23/95 (24%), Positives = 43/95 (45%), Gaps = 7/95 (7%)
Frame = +3
Query: 276 DHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDN-------GKNPALVETFKD 434
+ + +AAG H++ + SG ++ G + GR+ K P+ V ++
Sbjct: 153 EKVVCIAAGLRHAVAATASGIVFQWGTG-LASCGRRLCPGQTLPLFFTAKEPSRVTGLEN 211
Query: 435 CTISTIACGLQHSLAIDEWGQPFSWGSDSMGQLGN 539
+ G HS ++ + G+ + WGS+ GQL N
Sbjct: 212 SKAMCVLAGSDHSASLTDAGEVYVWGSNKHGQLAN 246
Score = 31.5 bits (68), Expect = 4.0
Identities = 19/70 (27%), Positives = 31/70 (44%)
Frame = +3
Query: 270 ESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTIST 449
E+ V AG HS L+++G +Y G+N GQL + F++ ++
Sbjct: 210 ENSKAMCVLAGSDHSASLTDAGEVYVWGSNKHGQLANEAAFLPVPQKIEAHCFQNEKVTA 269
Query: 450 IACGLQHSLA 479
I G H +A
Sbjct: 270 IWSGWTHLVA 279
>AJ243950-1|CAB60832.1| 458|Homo sapiens deafness locus associated
putative guanine nucleotide exchange factor protein.
Length = 458
Score = 101 bits (242), Expect = 3e-21
Identities = 66/234 (28%), Positives = 112/234 (47%), Gaps = 8/234 (3%)
Frame = +3
Query: 174 MFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCG 353
+F WG ++ +L + + D+++ L+ + + ++ + G HS +++ G L+ CG
Sbjct: 17 LFAWGANSYGQLGLGHKE--DVLLPQQLNDFCKPRSVRRITGGGGHSAVVTDGGDLFVCG 74
Query: 354 NNDVGQLGR-QTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQ 530
N GQLG TE P ++ C I +ACG ++ + E GQ S GS+S GQ
Sbjct: 75 LNKDGQLGLGHTEDIPYFTPC--KSLFGCPIQQVACGWDFTIMLTENGQVLSCGSNSFGQ 132
Query: 531 LGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTIS 710
LG G P+ ++ L + V+ +A G H+VA T SG ++ WG CG
Sbjct: 133 LGVPHGPRRCVVPQAIE-LHKEKVVCIAAGLRHAVAATASGIVFQWG-TGLASCGRRLCP 190
Query: 711 NKEM-------SPQHISSLIGVPIALIACGNNHTFVLSKSGAVFGWGKNTHGXL 851
+ + P ++ L + G++H+ L+ +G V+ WG N HG L
Sbjct: 191 GQTLPLFFTAKEPSRVTGLENSKAMCVLAGSDHSASLTDAGEVYVWGSNKHGQL 244
Score = 89.4 bits (212), Expect = 1e-17
Identities = 64/199 (32%), Positives = 96/199 (48%), Gaps = 8/199 (4%)
Frame = +3
Query: 282 IQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACG 461
IQ VA G ++ L+ +G + SCG+N GQLG P +E K+ + IA G
Sbjct: 103 IQQVACGWDFTIMLTENGQVLSCGSNSFGQLGVPHGPRRCVVPQAIELHKEKVVC-IAAG 161
Query: 462 LQHSLAIDEWGQPFSWGSD--SMGQL---GNNLGAHAQDK-PKFVKGLATKNVIQVACGA 623
L+H++A G F WG+ S G+ G L K P V GL + V G+
Sbjct: 162 LRHAVAATASGIVFQWGTGLASCGRRLCPGQTLPLFFTAKEPSRVTGLENSKAMCVLAGS 221
Query: 624 YHSVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISS--LIGVPIALIACGNNHTFV 797
HS +LT++G++Y WG+N +GQ L + PQ I + + I G H
Sbjct: 222 DHSASLTDAGEVYVWGSNKHGQ--LANEAAFLPVPQKIEAHCFQNEKVTAIWSGWTHLVA 279
Query: 798 LSKSGAVFGWGKNTHGXLG 854
+++G +F WG+ +G LG
Sbjct: 280 QTETGKMFTWGRADYGQLG 298
Score = 82.2 bits (194), Expect = 2e-15
Identities = 56/192 (29%), Positives = 89/192 (46%), Gaps = 15/192 (7%)
Frame = +3
Query: 270 ESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTIST 449
E+ V AG HS L+++G +Y G+N GQL + F++ ++
Sbjct: 210 ENSKAMCVLAGSDHSASLTDAGEVYVWGSNKHGQLANEAAFLPVPQKIEAHCFQNEKVTA 269
Query: 450 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNL----GAHAQDKPKFVKGLATKNVI---- 605
I G H +A E G+ F+WG GQLG L G + + F+ N +
Sbjct: 270 IWSGWTHLVAQTETGKMFTWGRADYGQLGRKLETYEGWKLEKQDSFLPCSRPPNSMPSSP 329
Query: 606 -------QVACGAYHSVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIA 764
+V+CG+ H++A+ G YSWG N +G CG GT +N +P+ + +L+
Sbjct: 330 HCLTGATEVSCGSEHNLAIIG-GVCYSWGWNEHGMCGDGTEAN-VWAPKPVQALLSSSGL 387
Query: 765 LIACGNNHTFVL 800
L+ CG H+ L
Sbjct: 388 LVGCGAGHSLAL 399
Score = 72.5 bits (170), Expect = 2e-12
Identities = 47/122 (38%), Positives = 68/122 (55%), Gaps = 4/122 (3%)
Frame = +3
Query: 501 FSWGSDSMGQLGNNLGAHAQDK--PKFVKGLAT-KNVIQVACGAYHSVALTNSGDLYSWG 671
F+WG++S GQLG LG H +D P+ + ++V ++ G HS +T+ GDL+ G
Sbjct: 18 FAWGANSYGQLG--LG-HKEDVLLPQQLNDFCKPRSVRRITGGGGHSAVVTDGGDLFVCG 74
Query: 672 ANSYGQCGLG-TISNKEMSPQHISSLIGVPIALIACGNNHTFVLSKSGAVFGWGKNTHGX 848
N GQ GLG T +P SL G PI +ACG + T +L+++G V G N+ G
Sbjct: 75 LNKDGQLGLGHTEDIPYFTP--CKSLFGCPIQQVACGWDFTIMLTENGQVLSCGSNSFGQ 132
Query: 849 LG 854
LG
Sbjct: 133 LG 134
Score = 64.1 bits (149), Expect = 6e-10
Identities = 48/185 (25%), Positives = 91/185 (49%), Gaps = 15/185 (8%)
Frame = +3
Query: 132 ANSSY*KKLQNYKKMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFH 311
A S + L + +++ WG+ H +L + + + V + + +++ + A+ +G H
Sbjct: 219 AGSDHSASLTDAGEVYVWGSNKHGQLANEAAFLP--VPQKIEAHCFQNEKVTAIWSGWTH 276
Query: 312 SLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCT---------------IS 446
+ + +G +++ G D GQLGR+ E+ G ++F C+ +
Sbjct: 277 LVAQTETGKMFTWGRADYGQLGRKLETYEGWKLEKQDSFLPCSRPPNSMPSSPHCLTGAT 336
Query: 447 TIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAY 626
++CG +H+LAI G +SWG + G G+ A+ PK V+ L + + + V CGA
Sbjct: 337 EVSCGSEHNLAI-IGGVCYSWGWNEHGMCGDGTEANVW-APKPVQALLSSSGLLVGCGAG 394
Query: 627 HSVAL 641
HS+AL
Sbjct: 395 HSLAL 399
Score = 45.6 bits (103), Expect = 2e-04
Identities = 27/76 (35%), Positives = 38/76 (50%), Gaps = 1/76 (1%)
Frame = +3
Query: 630 SVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGV-PIALIACGNNHTFVLSK 806
S A + L++WGANSYGQ GLG + PQ ++ + I G H+ V++
Sbjct: 8 SEAAPAAAALFAWGANSYGQLGLGH-KEDVLLPQQLNDFCKPRSVRRITGGGGHSAVVTD 66
Query: 807 SGAVFGWGKNTHGXLG 854
G +F G N G LG
Sbjct: 67 GGDLFVCGLNKDGQLG 82
>BC142946-1|AAI42947.1| 457|Homo sapiens RCC2 protein protein.
Length = 457
Score = 97.5 bits (232), Expect = 5e-20
Identities = 66/205 (32%), Positives = 98/205 (47%), Gaps = 23/205 (11%)
Frame = +3
Query: 309 HSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDE 488
HSL ++ G L+S G N+ GQLG ++ + P L+E I + ACG H+LA+ E
Sbjct: 96 HSLLITTEGKLWSWGRNEKGQLGHG-DTKRVEAPRLIEGLSHEVIVSAACGRNHTLALTE 154
Query: 489 WGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 668
G F++G + MGQLG A P + + + ++ACGA S+ + G+LYS+
Sbjct: 155 TGSVFAFGENKMGQLGLGNQTDAVPSPAQIM-YNGQPITKMACGAEFSMIMDCKGNLYSF 213
Query: 669 GANSYGQCGLGTIS-----------NKEMSPQHISSLI------------GVPIALIACG 779
G YGQ G + + E+ P+ ++ I V + +ACG
Sbjct: 214 GCPEYGQLGHNSDGKFIARAQRIEYDCELVPRRVAIFIEKTKDGQILPVPNVVVRDVACG 273
Query: 780 NNHTFVLSKSGAVFGWGKNTHGXLG 854
NHT VL VF WG +G LG
Sbjct: 274 ANHTLVLDSQKRVFSWGFGGYGRLG 298
Score = 89.4 bits (212), Expect = 1e-17
Identities = 46/139 (33%), Positives = 78/139 (56%)
Frame = +3
Query: 438 TISTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVAC 617
T+ + +C HSL I G+ +SWG + GQLG+ + P+ ++GL+ + ++ AC
Sbjct: 87 TVVSGSCAA-HSLLITTEGKLWSWGRNEKGQLGHG-DTKRVEAPRLIEGLSHEVIVSAAC 144
Query: 618 GAYHSVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFV 797
G H++ALT +G ++++G N GQ GLG ++ SP I G PI +ACG + +
Sbjct: 145 GRNHTLALTETGSVFAFGENKMGQLGLGNQTDAVPSPAQI-MYNGQPITKMACGAEFSMI 203
Query: 798 LSKSGAVFGWGKNTHGXLG 854
+ G ++ +G +G LG
Sbjct: 204 MDCKGNLYSFGCPEYGQLG 222
Score = 87.0 bits (206), Expect = 8e-17
Identities = 72/245 (29%), Positives = 114/245 (46%), Gaps = 25/245 (10%)
Frame = +3
Query: 171 KMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSC 350
K++ WG +L G T V P L + + I + A G H+L L+ +G +++
Sbjct: 105 KLWSWGRNEKGQL---GHGDTKRVEAPRLIEGLSHEVIVSAACGRNHTLALTETGSVFAF 161
Query: 351 GNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQ 530
G N +GQLG ++D +PA + + I+ +ACG + S+ +D G +S+G GQ
Sbjct: 162 GENKMGQLGLGNQTDAVPSPAQI-MYNGQPITKMACGAEFSMIMDCKGNLYSFGCPEYGQ 220
Query: 531 LGNNLG----AHAQ-----------------DKPKFVKGLATKNVI--QVACGAYHSVAL 641
LG+N A AQ +K K + L NV+ VACGA H++ L
Sbjct: 221 LGHNSDGKFIARAQRIEYDCELVPRRVAIFIEKTKDGQILPVPNVVVRDVACGANHTLVL 280
Query: 642 TNSGDLYSWGANSYGQCGLGTISNKEMSPQHIS--SLIGVPIALIACGNNHTFVLSKSGA 815
+ ++SWG YG+ G EM P+ + G + I G +F +S+ G
Sbjct: 281 DSQKRVFSWGFGGYGRLGHAE-QKDEMVPRLVKLFDFPGRGASRIYAGYTCSFAVSEVGG 339
Query: 816 VFGWG 830
+F WG
Sbjct: 340 LFFWG 344
Score = 62.9 bits (146), Expect = 1e-09
Identities = 69/255 (27%), Positives = 109/255 (42%), Gaps = 28/255 (10%)
Frame = +3
Query: 174 MFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCG 353
+F +G +L + G+Q TD V P + I +A G S+ + G+LYS G
Sbjct: 158 VFAFGENKMGQLGL-GNQ-TDAVPSPAQIMYN-GQPITKMACGAEFSMIMDCKGNLYSFG 214
Query: 354 NNDVGQLGRQT-----------ESDNGKNPALVETFKDCT------------ISTIACGL 464
+ GQLG + E D P V F + T + +ACG
Sbjct: 215 CPEYGQLGHNSDGKFIARAQRIEYDCELVPRRVAIFIEKTKDGQILPVPNVVVRDVACGA 274
Query: 465 QHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDK--PKFVK--GLATKNVIQVACGAYHS 632
H+L +D + FSWG G+LG+ A +D+ P+ VK + ++ G S
Sbjct: 275 NHTLVLDSQKRVFSWGFGGYGRLGH---AEQKDEMVPRLVKLFDFPGRGASRIYAGYTCS 331
Query: 633 VALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFVLSKSG 812
A++ G L+ WGA + T M P+ + L G I +ACG + + +++
Sbjct: 332 FAVSEVGGLFFWGATN-------TSRESTMYPKAVQDLCGWRIRSLACGKS-SIIVAADE 383
Query: 813 AVFGWGKN-THGXLG 854
+ WG + T G LG
Sbjct: 384 STISWGPSPTFGELG 398
>BC053908-1|AAH53908.1| 522|Homo sapiens RCC2 protein protein.
Length = 522
Score = 97.5 bits (232), Expect = 5e-20
Identities = 66/205 (32%), Positives = 98/205 (47%), Gaps = 23/205 (11%)
Frame = +3
Query: 309 HSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDE 488
HSL ++ G L+S G N+ GQLG ++ + P L+E I + ACG H+LA+ E
Sbjct: 161 HSLLITTEGKLWSWGRNEKGQLGHG-DTKRVEAPRLIEGLSHEVIVSAACGRNHTLALTE 219
Query: 489 WGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 668
G F++G + MGQLG A P + + + ++ACGA S+ + G+LYS+
Sbjct: 220 TGSVFAFGENKMGQLGLGNQTDAVPSPAQIM-YNGQPITKMACGAEFSMIMDCKGNLYSF 278
Query: 669 GANSYGQCGLGTIS-----------NKEMSPQHISSLI------------GVPIALIACG 779
G YGQ G + + E+ P+ ++ I V + +ACG
Sbjct: 279 GCPEYGQLGHNSDGKFIARAQRIEYDCELVPRRVAIFIEKTKDGQILPVPNVVVRDVACG 338
Query: 780 NNHTFVLSKSGAVFGWGKNTHGXLG 854
NHT VL VF WG +G LG
Sbjct: 339 ANHTLVLDSQKRVFSWGFGGYGRLG 363
Score = 89.4 bits (212), Expect = 1e-17
Identities = 46/139 (33%), Positives = 78/139 (56%)
Frame = +3
Query: 438 TISTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVAC 617
T+ + +C HSL I G+ +SWG + GQLG+ + P+ ++GL+ + ++ AC
Sbjct: 152 TVVSGSCAA-HSLLITTEGKLWSWGRNEKGQLGHG-DTKRVEAPRLIEGLSHEVIVSAAC 209
Query: 618 GAYHSVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFV 797
G H++ALT +G ++++G N GQ GLG ++ SP I G PI +ACG + +
Sbjct: 210 GRNHTLALTETGSVFAFGENKMGQLGLGNQTDAVPSPAQI-MYNGQPITKMACGAEFSMI 268
Query: 798 LSKSGAVFGWGKNTHGXLG 854
+ G ++ +G +G LG
Sbjct: 269 MDCKGNLYSFGCPEYGQLG 287
Score = 87.0 bits (206), Expect = 8e-17
Identities = 72/245 (29%), Positives = 114/245 (46%), Gaps = 25/245 (10%)
Frame = +3
Query: 171 KMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSC 350
K++ WG +L G T V P L + + I + A G H+L L+ +G +++
Sbjct: 170 KLWSWGRNEKGQL---GHGDTKRVEAPRLIEGLSHEVIVSAACGRNHTLALTETGSVFAF 226
Query: 351 GNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQ 530
G N +GQLG ++D +PA + + I+ +ACG + S+ +D G +S+G GQ
Sbjct: 227 GENKMGQLGLGNQTDAVPSPAQI-MYNGQPITKMACGAEFSMIMDCKGNLYSFGCPEYGQ 285
Query: 531 LGNNLG----AHAQ-----------------DKPKFVKGLATKNVI--QVACGAYHSVAL 641
LG+N A AQ +K K + L NV+ VACGA H++ L
Sbjct: 286 LGHNSDGKFIARAQRIEYDCELVPRRVAIFIEKTKDGQILPVPNVVVRDVACGANHTLVL 345
Query: 642 TNSGDLYSWGANSYGQCGLGTISNKEMSPQHIS--SLIGVPIALIACGNNHTFVLSKSGA 815
+ ++SWG YG+ G EM P+ + G + I G +F +S+ G
Sbjct: 346 DSQKRVFSWGFGGYGRLGHAE-QKDEMVPRLVKLFDFPGRGASQIYAGYTCSFAVSEVGG 404
Query: 816 VFGWG 830
+F WG
Sbjct: 405 LFFWG 409
Score = 64.5 bits (150), Expect = 5e-10
Identities = 70/255 (27%), Positives = 109/255 (42%), Gaps = 28/255 (10%)
Frame = +3
Query: 174 MFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCG 353
+F +G +L + G+Q TD V P + I +A G S+ + G+LYS G
Sbjct: 223 VFAFGENKMGQLGL-GNQ-TDAVPSPAQIMYN-GQPITKMACGAEFSMIMDCKGNLYSFG 279
Query: 354 NNDVGQLGRQT-----------ESDNGKNPALVETFKDCT------------ISTIACGL 464
+ GQLG + E D P V F + T + +ACG
Sbjct: 280 CPEYGQLGHNSDGKFIARAQRIEYDCELVPRRVAIFIEKTKDGQILPVPNVVVRDVACGA 339
Query: 465 QHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDK--PKFVK--GLATKNVIQVACGAYHS 632
H+L +D + FSWG G+LG+ A +D+ P+ VK + Q+ G S
Sbjct: 340 NHTLVLDSQKRVFSWGFGGYGRLGH---AEQKDEMVPRLVKLFDFPGRGASQIYAGYTCS 396
Query: 633 VALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFVLSKSG 812
A++ G L+ WGA + T M P+ + L G I +ACG + + +++
Sbjct: 397 FAVSEVGGLFFWGATN-------TSRESTMYPKAVQDLCGWRIRSLACGKS-SIIVAADE 448
Query: 813 AVFGWGKN-THGXLG 854
+ WG + T G LG
Sbjct: 449 STISWGPSPTFGELG 463
>BC042141-1|AAH42141.1| 522|Homo sapiens regulator of chromosome
condensation 2 protein.
Length = 522
Score = 97.5 bits (232), Expect = 5e-20
Identities = 66/205 (32%), Positives = 98/205 (47%), Gaps = 23/205 (11%)
Frame = +3
Query: 309 HSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDE 488
HSL ++ G L+S G N+ GQLG ++ + P L+E I + ACG H+LA+ E
Sbjct: 161 HSLLITTEGKLWSWGRNEKGQLGHG-DTKRVEAPRLIEGLSHEVIVSAACGRNHTLALTE 219
Query: 489 WGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 668
G F++G + MGQLG A P + + + ++ACGA S+ + G+LYS+
Sbjct: 220 TGSVFAFGENKMGQLGLGNQTDAVPSPAQIM-YNGQPITKMACGAEFSMIMDCKGNLYSF 278
Query: 669 GANSYGQCGLGTIS-----------NKEMSPQHISSLI------------GVPIALIACG 779
G YGQ G + + E+ P+ ++ I V + +ACG
Sbjct: 279 GCPEYGQLGHNSDGKFIARAQRIEYDCELVPRRVAIFIEKTKDGQILPVPNVVVRDVACG 338
Query: 780 NNHTFVLSKSGAVFGWGKNTHGXLG 854
NHT VL VF WG +G LG
Sbjct: 339 ANHTLVLDSQKRVFSWGFGGYGRLG 363
Score = 89.4 bits (212), Expect = 1e-17
Identities = 46/139 (33%), Positives = 78/139 (56%)
Frame = +3
Query: 438 TISTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVAC 617
T+ + +C HSL I G+ +SWG + GQLG+ + P+ ++GL+ + ++ AC
Sbjct: 152 TVVSGSCAA-HSLLITTEGKLWSWGRNEKGQLGHG-DTKRVEAPRLIEGLSHEVIVSAAC 209
Query: 618 GAYHSVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFV 797
G H++ALT +G ++++G N GQ GLG ++ SP I G PI +ACG + +
Sbjct: 210 GRNHTLALTETGSVFAFGENKMGQLGLGNQTDAVPSPAQI-MYNGQPITKMACGAEFSMI 268
Query: 798 LSKSGAVFGWGKNTHGXLG 854
+ G ++ +G +G LG
Sbjct: 269 MDCKGNLYSFGCPEYGQLG 287
Score = 87.0 bits (206), Expect = 8e-17
Identities = 72/245 (29%), Positives = 114/245 (46%), Gaps = 25/245 (10%)
Frame = +3
Query: 171 KMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSC 350
K++ WG +L G T V P L + + I + A G H+L L+ +G +++
Sbjct: 170 KLWSWGRNEKGQL---GHGDTKRVEAPRLIEGLSHEVIVSAACGRNHTLALTETGSVFAF 226
Query: 351 GNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQ 530
G N +GQLG ++D +PA + + I+ +ACG + S+ +D G +S+G GQ
Sbjct: 227 GENKMGQLGLGNQTDAVPSPAQI-MYNGQPITKMACGAEFSMIMDCKGNLYSFGCPEYGQ 285
Query: 531 LGNNLG----AHAQ-----------------DKPKFVKGLATKNVI--QVACGAYHSVAL 641
LG+N A AQ +K K + L NV+ VACGA H++ L
Sbjct: 286 LGHNSDGKFIARAQRIEYDCELVPRRVAIFIEKTKDGQILPVPNVVVRDVACGANHTLVL 345
Query: 642 TNSGDLYSWGANSYGQCGLGTISNKEMSPQHIS--SLIGVPIALIACGNNHTFVLSKSGA 815
+ ++SWG YG+ G EM P+ + G + I G +F +S+ G
Sbjct: 346 DSQKRVFSWGFGGYGRLGHAE-QKDEMVPRLVKLFDFPGRGASQIYAGYTCSFAVSEVGG 404
Query: 816 VFGWG 830
+F WG
Sbjct: 405 LFFWG 409
Score = 64.5 bits (150), Expect = 5e-10
Identities = 70/255 (27%), Positives = 109/255 (42%), Gaps = 28/255 (10%)
Frame = +3
Query: 174 MFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCG 353
+F +G +L + G+Q TD V P + I +A G S+ + G+LYS G
Sbjct: 223 VFAFGENKMGQLGL-GNQ-TDAVPSPAQIMYN-GQPITKMACGAEFSMIMDCKGNLYSFG 279
Query: 354 NNDVGQLGRQT-----------ESDNGKNPALVETFKDCT------------ISTIACGL 464
+ GQLG + E D P V F + T + +ACG
Sbjct: 280 CPEYGQLGHNSDGKFIARAQRIEYDCELVPRRVAIFIEKTKDGQILPVPNVVVRDVACGA 339
Query: 465 QHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDK--PKFVK--GLATKNVIQVACGAYHS 632
H+L +D + FSWG G+LG+ A +D+ P+ VK + Q+ G S
Sbjct: 340 NHTLVLDSQKRVFSWGFGGYGRLGH---AEQKDEMVPRLVKLFDFPGRGASQIYAGYTCS 396
Query: 633 VALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFVLSKSG 812
A++ G L+ WGA + T M P+ + L G I +ACG + + +++
Sbjct: 397 FAVSEVGGLFFWGATN-------TSRESTMYPKAVQDLCGWRIRSLACGKS-SIIVAADE 448
Query: 813 AVFGWGKN-THGXLG 854
+ WG + T G LG
Sbjct: 449 STISWGPSPTFGELG 463
>AL359612-1|CAB94882.1| 333|Homo sapiens hypothetical protein
protein.
Length = 333
Score = 97.5 bits (232), Expect = 5e-20
Identities = 66/205 (32%), Positives = 98/205 (47%), Gaps = 23/205 (11%)
Frame = +3
Query: 309 HSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDE 488
HSL ++ G L+S G N+ GQLG ++ + P L+E I + ACG H+LA+ E
Sbjct: 17 HSLLITTEGKLWSWGRNEKGQLGHG-DTKRVEAPRLIEGLSHEVIVSAACGRNHTLALTE 75
Query: 489 WGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 668
G F++G + MGQLG A P + + + ++ACGA S+ + G+LYS+
Sbjct: 76 TGSVFAFGENKMGQLGLGNQTDAVPSPAQIM-YNGQPITKMACGAEFSMIMDCKGNLYSF 134
Query: 669 GANSYGQCGLGTIS-----------NKEMSPQHISSLI------------GVPIALIACG 779
G YGQ G + + E+ P+ ++ I V + +ACG
Sbjct: 135 GCPEYGQLGHNSDGKFIARAQRIEYDCELVPRRVAIFIEKTKDGQILPVPNVVVRDVACG 194
Query: 780 NNHTFVLSKSGAVFGWGKNTHGXLG 854
NHT VL VF WG +G LG
Sbjct: 195 ANHTLVLDSQKRVFSWGFGGYGRLG 219
Score = 89.4 bits (212), Expect = 1e-17
Identities = 46/139 (33%), Positives = 78/139 (56%)
Frame = +3
Query: 438 TISTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVAC 617
T+ + +C HSL I G+ +SWG + GQLG+ + P+ ++GL+ + ++ AC
Sbjct: 8 TVVSGSCAA-HSLLITTEGKLWSWGRNEKGQLGHG-DTKRVEAPRLIEGLSHEVIVSAAC 65
Query: 618 GAYHSVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFV 797
G H++ALT +G ++++G N GQ GLG ++ SP I G PI +ACG + +
Sbjct: 66 GRNHTLALTETGSVFAFGENKMGQLGLGNQTDAVPSPAQI-MYNGQPITKMACGAEFSMI 124
Query: 798 LSKSGAVFGWGKNTHGXLG 854
+ G ++ +G +G LG
Sbjct: 125 MDCKGNLYSFGCPEYGQLG 143
Score = 87.0 bits (206), Expect = 8e-17
Identities = 72/245 (29%), Positives = 114/245 (46%), Gaps = 25/245 (10%)
Frame = +3
Query: 171 KMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSC 350
K++ WG +L G T V P L + + I + A G H+L L+ +G +++
Sbjct: 26 KLWSWGRNEKGQL---GHGDTKRVEAPRLIEGLSHEVIVSAACGRNHTLALTETGSVFAF 82
Query: 351 GNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQ 530
G N +GQLG ++D +PA + + I+ +ACG + S+ +D G +S+G GQ
Sbjct: 83 GENKMGQLGLGNQTDAVPSPAQI-MYNGQPITKMACGAEFSMIMDCKGNLYSFGCPEYGQ 141
Query: 531 LGNNLG----AHAQ-----------------DKPKFVKGLATKNVI--QVACGAYHSVAL 641
LG+N A AQ +K K + L NV+ VACGA H++ L
Sbjct: 142 LGHNSDGKFIARAQRIEYDCELVPRRVAIFIEKTKDGQILPVPNVVVRDVACGANHTLVL 201
Query: 642 TNSGDLYSWGANSYGQCGLGTISNKEMSPQHIS--SLIGVPIALIACGNNHTFVLSKSGA 815
+ ++SWG YG+ G EM P+ + G + I G +F +S+ G
Sbjct: 202 DSQKRVFSWGFGGYGRLGHAE-QKDEMVPRLVKLFDFPGRGASQIYAGYTCSFAVSEVGG 260
Query: 816 VFGWG 830
+F WG
Sbjct: 261 LFFWG 265
Score = 64.5 bits (150), Expect = 5e-10
Identities = 70/255 (27%), Positives = 109/255 (42%), Gaps = 28/255 (10%)
Frame = +3
Query: 174 MFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCG 353
+F +G +L + G+Q TD V P + I +A G S+ + G+LYS G
Sbjct: 79 VFAFGENKMGQLGL-GNQ-TDAVPSPAQIMYN-GQPITKMACGAEFSMIMDCKGNLYSFG 135
Query: 354 NNDVGQLGRQT-----------ESDNGKNPALVETFKDCT------------ISTIACGL 464
+ GQLG + E D P V F + T + +ACG
Sbjct: 136 CPEYGQLGHNSDGKFIARAQRIEYDCELVPRRVAIFIEKTKDGQILPVPNVVVRDVACGA 195
Query: 465 QHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDK--PKFVK--GLATKNVIQVACGAYHS 632
H+L +D + FSWG G+LG+ A +D+ P+ VK + Q+ G S
Sbjct: 196 NHTLVLDSQKRVFSWGFGGYGRLGH---AEQKDEMVPRLVKLFDFPGRGASQIYAGYTCS 252
Query: 633 VALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFVLSKSG 812
A++ G L+ WGA + T M P+ + L G I +ACG + + +++
Sbjct: 253 FAVSEVGGLFFWGATN-------TSRESTMYPKAVQDLCGWRIRSLACGKS-SIIVAADE 304
Query: 813 AVFGWGKN-THGXLG 854
+ WG + T G LG
Sbjct: 305 STISWGPSPTFGELG 319
>AJ421269-1|CAD13148.1| 522|Homo sapiens RCC1-like protein protein.
Length = 522
Score = 97.5 bits (232), Expect = 5e-20
Identities = 66/205 (32%), Positives = 98/205 (47%), Gaps = 23/205 (11%)
Frame = +3
Query: 309 HSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDE 488
HSL ++ G L+S G N+ GQLG ++ + P L+E I + ACG H+LA+ E
Sbjct: 161 HSLLITTEGKLWSWGRNEKGQLGHG-DTKRVEAPRLIEGLSHEVIVSAACGRNHTLALTE 219
Query: 489 WGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 668
G F++G + MGQLG A P + + + ++ACGA S+ + G+LYS+
Sbjct: 220 TGSVFAFGENKMGQLGLGNQTDAVPSPAQIM-YNGQPITKMACGAEFSMIMDCKGNLYSF 278
Query: 669 GANSYGQCGLGTIS-----------NKEMSPQHISSLI------------GVPIALIACG 779
G YGQ G + + E+ P+ ++ I V + +ACG
Sbjct: 279 GCPEYGQLGHNSDGKFIARAQRIEYDCELVPRRVAIFIEKTKDGQILPVPNVVVRDVACG 338
Query: 780 NNHTFVLSKSGAVFGWGKNTHGXLG 854
NHT VL VF WG +G LG
Sbjct: 339 ANHTLVLDSQKRVFSWGFGGYGRLG 363
Score = 89.4 bits (212), Expect = 1e-17
Identities = 46/139 (33%), Positives = 78/139 (56%)
Frame = +3
Query: 438 TISTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVAC 617
T+ + +C HSL I G+ +SWG + GQLG+ + P+ ++GL+ + ++ AC
Sbjct: 152 TVVSGSCAA-HSLLITTEGKLWSWGRNEKGQLGHG-DTKRVEAPRLIEGLSHEVIVSAAC 209
Query: 618 GAYHSVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFV 797
G H++ALT +G ++++G N GQ GLG ++ SP I G PI +ACG + +
Sbjct: 210 GRNHTLALTETGSVFAFGENKMGQLGLGNQTDAVPSPAQI-MYNGQPITKMACGAEFSMI 268
Query: 798 LSKSGAVFGWGKNTHGXLG 854
+ G ++ +G +G LG
Sbjct: 269 MDCKGNLYSFGCPEYGQLG 287
Score = 87.0 bits (206), Expect = 8e-17
Identities = 72/245 (29%), Positives = 114/245 (46%), Gaps = 25/245 (10%)
Frame = +3
Query: 171 KMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSC 350
K++ WG +L G T V P L + + I + A G H+L L+ +G +++
Sbjct: 170 KLWSWGRNEKGQL---GHGDTKRVEAPRLIEGLSHEVIVSAACGRNHTLALTETGSVFAF 226
Query: 351 GNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQ 530
G N +GQLG ++D +PA + + I+ +ACG + S+ +D G +S+G GQ
Sbjct: 227 GENKMGQLGLGNQTDAVPSPAQI-MYNGQPITKMACGAEFSMIMDCKGNLYSFGCPEYGQ 285
Query: 531 LGNNLG----AHAQ-----------------DKPKFVKGLATKNVI--QVACGAYHSVAL 641
LG+N A AQ +K K + L NV+ VACGA H++ L
Sbjct: 286 LGHNSDGKFIARAQRIEYDCELVPRRVAIFIEKTKDGQILPVPNVVVRDVACGANHTLVL 345
Query: 642 TNSGDLYSWGANSYGQCGLGTISNKEMSPQHIS--SLIGVPIALIACGNNHTFVLSKSGA 815
+ ++SWG YG+ G EM P+ + G + I G +F +S+ G
Sbjct: 346 DSQKRVFSWGFGGYGRLGHAE-QKDEMVPRLVKLFDFPGRGASQIYAGYTCSFAVSEVGG 404
Query: 816 VFGWG 830
+F WG
Sbjct: 405 LFFWG 409
Score = 64.5 bits (150), Expect = 5e-10
Identities = 70/255 (27%), Positives = 109/255 (42%), Gaps = 28/255 (10%)
Frame = +3
Query: 174 MFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCG 353
+F +G +L + G+Q TD V P + I +A G S+ + G+LYS G
Sbjct: 223 VFAFGENKMGQLGL-GNQ-TDAVPSPAQIMYN-GQPITKMACGAEFSMIMDCKGNLYSFG 279
Query: 354 NNDVGQLGRQT-----------ESDNGKNPALVETFKDCT------------ISTIACGL 464
+ GQLG + E D P V F + T + +ACG
Sbjct: 280 CPEYGQLGHNSDGKFIARAQRIEYDCELVPRRVAIFIEKTKDGQILPVPNVVVRDVACGA 339
Query: 465 QHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDK--PKFVK--GLATKNVIQVACGAYHS 632
H+L +D + FSWG G+LG+ A +D+ P+ VK + Q+ G S
Sbjct: 340 NHTLVLDSQKRVFSWGFGGYGRLGH---AEQKDEMVPRLVKLFDFPGRGASQIYAGYTCS 396
Query: 633 VALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFVLSKSG 812
A++ G L+ WGA + T M P+ + L G I +ACG + + +++
Sbjct: 397 FAVSEVGGLFFWGATN-------TSRESTMYPKAVQDLCGWRIRSLACGKS-SIIVAADE 448
Query: 813 AVFGWGKN-THGXLG 854
+ WG + T G LG
Sbjct: 449 STISWGPSPTFGELG 463
>AB040903-1|BAA95994.1| 564|Homo sapiens KIAA1470 protein protein.
Length = 564
Score = 97.5 bits (232), Expect = 5e-20
Identities = 66/205 (32%), Positives = 98/205 (47%), Gaps = 23/205 (11%)
Frame = +3
Query: 309 HSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDE 488
HSL ++ G L+S G N+ GQLG ++ + P L+E I + ACG H+LA+ E
Sbjct: 203 HSLLITTEGKLWSWGRNEKGQLGHG-DTKRVEAPRLIEGLSHEVIVSAACGRNHTLALTE 261
Query: 489 WGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 668
G F++G + MGQLG A P + + + ++ACGA S+ + G+LYS+
Sbjct: 262 TGSVFAFGENKMGQLGLGNQTDAVPSPAQIM-YNGQPITKMACGAEFSMIMDCKGNLYSF 320
Query: 669 GANSYGQCGLGTIS-----------NKEMSPQHISSLI------------GVPIALIACG 779
G YGQ G + + E+ P+ ++ I V + +ACG
Sbjct: 321 GCPEYGQLGHNSDGKFIARAQRIEYDCELVPRRVAIFIEKTKDGQILPVPNVVVRDVACG 380
Query: 780 NNHTFVLSKSGAVFGWGKNTHGXLG 854
NHT VL VF WG +G LG
Sbjct: 381 ANHTLVLDSQKRVFSWGFGGYGRLG 405
Score = 89.4 bits (212), Expect = 1e-17
Identities = 46/139 (33%), Positives = 78/139 (56%)
Frame = +3
Query: 438 TISTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVAC 617
T+ + +C HSL I G+ +SWG + GQLG+ + P+ ++GL+ + ++ AC
Sbjct: 194 TVVSGSCAA-HSLLITTEGKLWSWGRNEKGQLGHG-DTKRVEAPRLIEGLSHEVIVSAAC 251
Query: 618 GAYHSVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFV 797
G H++ALT +G ++++G N GQ GLG ++ SP I G PI +ACG + +
Sbjct: 252 GRNHTLALTETGSVFAFGENKMGQLGLGNQTDAVPSPAQI-MYNGQPITKMACGAEFSMI 310
Query: 798 LSKSGAVFGWGKNTHGXLG 854
+ G ++ +G +G LG
Sbjct: 311 MDCKGNLYSFGCPEYGQLG 329
Score = 87.0 bits (206), Expect = 8e-17
Identities = 72/245 (29%), Positives = 114/245 (46%), Gaps = 25/245 (10%)
Frame = +3
Query: 171 KMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSC 350
K++ WG +L G T V P L + + I + A G H+L L+ +G +++
Sbjct: 212 KLWSWGRNEKGQL---GHGDTKRVEAPRLIEGLSHEVIVSAACGRNHTLALTETGSVFAF 268
Query: 351 GNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQ 530
G N +GQLG ++D +PA + + I+ +ACG + S+ +D G +S+G GQ
Sbjct: 269 GENKMGQLGLGNQTDAVPSPAQI-MYNGQPITKMACGAEFSMIMDCKGNLYSFGCPEYGQ 327
Query: 531 LGNNLG----AHAQ-----------------DKPKFVKGLATKNVI--QVACGAYHSVAL 641
LG+N A AQ +K K + L NV+ VACGA H++ L
Sbjct: 328 LGHNSDGKFIARAQRIEYDCELVPRRVAIFIEKTKDGQILPVPNVVVRDVACGANHTLVL 387
Query: 642 TNSGDLYSWGANSYGQCGLGTISNKEMSPQHIS--SLIGVPIALIACGNNHTFVLSKSGA 815
+ ++SWG YG+ G EM P+ + G + I G +F +S+ G
Sbjct: 388 DSQKRVFSWGFGGYGRLGHAE-QKDEMVPRLVKLFDFPGRGASQIYAGYTCSFAVSEVGG 446
Query: 816 VFGWG 830
+F WG
Sbjct: 447 LFFWG 451
Score = 64.5 bits (150), Expect = 5e-10
Identities = 70/255 (27%), Positives = 109/255 (42%), Gaps = 28/255 (10%)
Frame = +3
Query: 174 MFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCG 353
+F +G +L + G+Q TD V P + I +A G S+ + G+LYS G
Sbjct: 265 VFAFGENKMGQLGL-GNQ-TDAVPSPAQIMYN-GQPITKMACGAEFSMIMDCKGNLYSFG 321
Query: 354 NNDVGQLGRQT-----------ESDNGKNPALVETFKDCT------------ISTIACGL 464
+ GQLG + E D P V F + T + +ACG
Sbjct: 322 CPEYGQLGHNSDGKFIARAQRIEYDCELVPRRVAIFIEKTKDGQILPVPNVVVRDVACGA 381
Query: 465 QHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDK--PKFVK--GLATKNVIQVACGAYHS 632
H+L +D + FSWG G+LG+ A +D+ P+ VK + Q+ G S
Sbjct: 382 NHTLVLDSQKRVFSWGFGGYGRLGH---AEQKDEMVPRLVKLFDFPGRGASQIYAGYTCS 438
Query: 633 VALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFVLSKSG 812
A++ G L+ WGA + T M P+ + L G I +ACG + + +++
Sbjct: 439 FAVSEVGGLFFWGATN-------TSRESTMYPKAVQDLCGWRIRSLACGKS-SIIVAADE 490
Query: 813 AVFGWGKN-THGXLG 854
+ WG + T G LG
Sbjct: 491 STISWGPSPTFGELG 505
>BC113705-1|AAI13706.1| 692|Homo sapiens NIMA (never in mitosis gene
a)- related kinase 8 protein.
Length = 692
Score = 93.5 bits (222), Expect = 9e-19
Identities = 63/228 (27%), Positives = 103/228 (45%), Gaps = 13/228 (5%)
Frame = +3
Query: 210 CIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTE 389
C+ +TD + +PT+ + + VA G H L LS L++ G D G+LG T
Sbjct: 422 CLGHGSLTD-ISQPTIVEALLGYEMVQVACGASHVLALSTERELFAWGRGDSGRLGLGTR 480
Query: 390 SDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNN---LGAHAQ 560
+ P V + CG+ S+ + GQ + GS+ +LG + LG
Sbjct: 481 ESHSC-PQQVPMPPGQEAQRVVCGIDSSMILTVPGQALACGSNRFNKLGLDHLSLGEEPV 539
Query: 561 DKPKFVKGLA----------TKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTIS 710
+ + L+ + ++ + G HS A+T SGD Y++G+N +GQ G T
Sbjct: 540 PHQQVEEALSFTLLGSAPLDQEPLLSIDLGTAHSAAVTASGDCYTFGSNQHGQLGTNTRR 599
Query: 711 NKEMSPQHISSLIGVPIALIACGNNHTFVLSKSGAVFGWGKNTHGXLG 854
+P + L G+ +A++ACG+ T + V+ WGK G LG
Sbjct: 600 GSR-APCKVQGLEGIKMAMVACGDAFTVAIGAESEVYSWGKGARGRLG 646
Score = 74.1 bits (174), Expect = 6e-13
Identities = 43/139 (30%), Positives = 66/139 (47%)
Frame = +3
Query: 438 TISTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVAC 617
TI +ACG + + + G ++GS S G LG+ +P V+ L ++QVAC
Sbjct: 392 TIKHVACGDFFTACLTDRGIIMTFGSGSNGCLGHGSLTDIS-QPTIVEALLGYEMVQVAC 450
Query: 618 GAYHSVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFV 797
GA H +AL+ +L++WG G+ GLGT PQ + G + CG + + +
Sbjct: 451 GASHVLALSTERELFAWGRGDSGRLGLGT-RESHSCPQQVPMPPGQEAQRVVCGIDSSMI 509
Query: 798 LSKSGAVFGWGKNTHGXLG 854
L+ G G N LG
Sbjct: 510 LTVPGQALACGSNRFNKLG 528
Score = 46.0 bits (104), Expect = 2e-04
Identities = 30/91 (32%), Positives = 43/91 (47%), Gaps = 6/91 (6%)
Frame = +3
Query: 600 VIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTISN--KEMSPQHISSLI----GVPI 761
V+QVA G +T SG L W A G G + ++ PQ IS + GV I
Sbjct: 334 VVQVAAGRTQKAGVTRSGRLILWEAPPLGAGGGSLLPGAVEQPQPQFISRFLEGQSGVTI 393
Query: 762 ALIACGNNHTFVLSKSGAVFGWGKNTHGXLG 854
+ACG+ T L+ G + +G ++G LG
Sbjct: 394 KHVACGDFFTACLTDRGIIMTFGSGSNGCLG 424
Score = 31.5 bits (68), Expect = 4.0
Identities = 14/56 (25%), Positives = 28/56 (50%)
Frame = +3
Query: 291 VAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIAC 458
VA G+ ++ + +YS G G+LGR+ E P ++ T+++++C
Sbjct: 618 VACGDAFTVAIGAESEVYSWGKGARGRLGRRDEDAGLPRPVQLDETHPYTVTSVSC 673
>BC112240-1|AAI12241.1| 692|Homo sapiens NIMA-related kinase 8
protein.
Length = 692
Score = 93.5 bits (222), Expect = 9e-19
Identities = 63/228 (27%), Positives = 103/228 (45%), Gaps = 13/228 (5%)
Frame = +3
Query: 210 CIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTE 389
C+ +TD + +PT+ + + VA G H L LS L++ G D G+LG T
Sbjct: 422 CLGHGSLTD-ISQPTIVEALLGYEMVQVACGASHVLALSTERELFAWGRGDSGRLGLGTR 480
Query: 390 SDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNN---LGAHAQ 560
+ P V + CG+ S+ + GQ + GS+ +LG + LG
Sbjct: 481 ESHSC-PQQVPMPPGQEAQRVVCGIDSSMILTVPGQALACGSNRFNKLGLDHLSLGEEPV 539
Query: 561 DKPKFVKGLA----------TKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTIS 710
+ + L+ + ++ + G HS A+T SGD Y++G+N +GQ G T
Sbjct: 540 PHQQVEEALSFTLLGSAPLDQEPLLSIDLGTAHSAAVTASGDCYTFGSNQHGQLGTNTRR 599
Query: 711 NKEMSPQHISSLIGVPIALIACGNNHTFVLSKSGAVFGWGKNTHGXLG 854
+P + L G+ +A++ACG+ T + V+ WGK G LG
Sbjct: 600 GSR-APCKVQGLEGIKMAMVACGDAFTVAIGAESEVYSWGKGARGRLG 646
Score = 74.1 bits (174), Expect = 6e-13
Identities = 43/139 (30%), Positives = 66/139 (47%)
Frame = +3
Query: 438 TISTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVAC 617
TI +ACG + + + G ++GS S G LG+ +P V+ L ++QVAC
Sbjct: 392 TIKHVACGDFFTACLTDRGIIMTFGSGSNGCLGHGSLTDIS-QPTIVEALLGYEMVQVAC 450
Query: 618 GAYHSVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFV 797
GA H +AL+ +L++WG G+ GLGT PQ + G + CG + + +
Sbjct: 451 GASHVLALSTERELFAWGRGDSGRLGLGT-RESHSCPQQVPMPPGQEAQRVVCGIDSSMI 509
Query: 798 LSKSGAVFGWGKNTHGXLG 854
L+ G G N LG
Sbjct: 510 LTVPGQALACGSNRFNKLG 528
Score = 46.0 bits (104), Expect = 2e-04
Identities = 30/91 (32%), Positives = 43/91 (47%), Gaps = 6/91 (6%)
Frame = +3
Query: 600 VIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTISN--KEMSPQHISSLI----GVPI 761
V+QVA G +T SG L W A G G + ++ PQ IS + GV I
Sbjct: 334 VVQVAAGRTQKAGVTRSGRLILWEAPPLGAGGGSLLPGAVEQPQPQFISRFLEGQSGVTI 393
Query: 762 ALIACGNNHTFVLSKSGAVFGWGKNTHGXLG 854
+ACG+ T L+ G + +G ++G LG
Sbjct: 394 KHVACGDFFTACLTDRGIIMTFGSGSNGCLG 424
Score = 31.5 bits (68), Expect = 4.0
Identities = 14/56 (25%), Positives = 28/56 (50%)
Frame = +3
Query: 291 VAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIAC 458
VA G+ ++ + +YS G G+LGR+ E P ++ T+++++C
Sbjct: 618 VACGDAFTVAIGAESEVYSWGKGARGRLGRRDEDAGLPRPVQLDETHPYTVTSVSC 673
>AY267371-1|AAP04006.1| 692|Homo sapiens NIMA-family kinase NEK8
protein.
Length = 692
Score = 93.5 bits (222), Expect = 9e-19
Identities = 63/228 (27%), Positives = 103/228 (45%), Gaps = 13/228 (5%)
Frame = +3
Query: 210 CIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTE 389
C+ +TD + +PT+ + + VA G H L LS L++ G D G+LG T
Sbjct: 422 CLGHGSLTD-ISQPTIVEALLGYEMVQVACGASHVLALSTERELFAWGRGDSGRLGLGTR 480
Query: 390 SDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNN---LGAHAQ 560
+ P V + CG+ S+ + GQ + GS+ +LG + LG
Sbjct: 481 ESHSC-PQQVPMPPGQEAQRVVCGIDSSMILTVPGQALACGSNRFNKLGLDHLSLGEEPV 539
Query: 561 DKPKFVKGLA----------TKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTIS 710
+ + L+ + ++ + G HS A+T SGD Y++G+N +GQ G T
Sbjct: 540 PHQQVEEALSFTLLGSAPLDQEPLLSIDLGTAHSAAVTASGDCYTFGSNQHGQLGTNTRR 599
Query: 711 NKEMSPQHISSLIGVPIALIACGNNHTFVLSKSGAVFGWGKNTHGXLG 854
+P + L G+ +A++ACG+ T + V+ WGK G LG
Sbjct: 600 GSR-APCKVQGLEGIKMAMVACGDAFTVAIGAESEVYSWGKGARGRLG 646
Score = 74.1 bits (174), Expect = 6e-13
Identities = 43/139 (30%), Positives = 66/139 (47%)
Frame = +3
Query: 438 TISTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVAC 617
TI +ACG + + + G ++GS S G LG+ +P V+ L ++QVAC
Sbjct: 392 TIKHVACGDFFTACLTDRGIIMTFGSGSNGCLGHGSLTDIS-QPTIVEALLGYEMVQVAC 450
Query: 618 GAYHSVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFV 797
GA H +AL+ +L++WG G+ GLGT PQ + G + CG + + +
Sbjct: 451 GASHVLALSTERELFAWGRGDSGRLGLGT-RESHSCPQQVPMPPGQEAQRVVCGIDSSMI 509
Query: 798 LSKSGAVFGWGKNTHGXLG 854
L+ G G N LG
Sbjct: 510 LTVPGQALACGSNRFNKLG 528
Score = 46.0 bits (104), Expect = 2e-04
Identities = 30/91 (32%), Positives = 43/91 (47%), Gaps = 6/91 (6%)
Frame = +3
Query: 600 VIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTISN--KEMSPQHISSLI----GVPI 761
V+QVA G +T SG L W A G G + ++ PQ IS + GV I
Sbjct: 334 VVQVAAGRTQKAGVTRSGRLILWEAPPLGAGGGSLLPGAVEQPQPQFISRFLEGQSGVTI 393
Query: 762 ALIACGNNHTFVLSKSGAVFGWGKNTHGXLG 854
+ACG+ T L+ G + +G ++G LG
Sbjct: 394 KHVACGDFFTACLTDRGIIMTFGSGSNGCLG 424
Score = 31.5 bits (68), Expect = 4.0
Identities = 14/56 (25%), Positives = 28/56 (50%)
Frame = +3
Query: 291 VAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIAC 458
VA G+ ++ + +YS G G+LGR+ E P ++ T+++++C
Sbjct: 618 VACGDAFTVAIGAESEVYSWGKGARGRLGRRDEDAGLPRPVQLDETHPYTVTSVSC 673
>AY242354-1|AAO88243.1| 692|Homo sapiens NIMA-related kinase 12a
protein.
Length = 692
Score = 93.5 bits (222), Expect = 9e-19
Identities = 63/228 (27%), Positives = 103/228 (45%), Gaps = 13/228 (5%)
Frame = +3
Query: 210 CIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTE 389
C+ +TD + +PT+ + + VA G H L LS L++ G D G+LG T
Sbjct: 422 CLGHGSLTD-ISQPTIVEALLGYEMVQVACGASHVLALSTERELFAWGRGDSGRLGLGTR 480
Query: 390 SDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNN---LGAHAQ 560
+ P V + CG+ S+ + GQ + GS+ +LG + LG
Sbjct: 481 ESHSC-PQQVPMPPGQEAQRVVCGIDSSMILTVPGQALACGSNRFNKLGLDHLSLGEEPV 539
Query: 561 DKPKFVKGLA----------TKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTIS 710
+ + L+ + ++ + G HS A+T SGD Y++G+N +GQ G T
Sbjct: 540 PHQQVEEALSFTLLGSAPLDQEPLLSIDLGTAHSAAVTASGDCYTFGSNQHGQLGTNTRR 599
Query: 711 NKEMSPQHISSLIGVPIALIACGNNHTFVLSKSGAVFGWGKNTHGXLG 854
+P + L G+ +A++ACG+ T + V+ WGK G LG
Sbjct: 600 GSR-APCKVQGLEGIKMAMVACGDAFTVAIGAESEVYSWGKGARGRLG 646
Score = 74.1 bits (174), Expect = 6e-13
Identities = 43/139 (30%), Positives = 66/139 (47%)
Frame = +3
Query: 438 TISTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVAC 617
TI +ACG + + + G ++GS S G LG+ +P V+ L ++QVAC
Sbjct: 392 TIKHVACGDFFTACLTDRGIIMTFGSGSNGCLGHGSLTDIS-QPTIVEALLGYEMVQVAC 450
Query: 618 GAYHSVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFV 797
GA H +AL+ +L++WG G+ GLGT PQ + G + CG + + +
Sbjct: 451 GASHVLALSTERELFAWGRGDSGRLGLGT-RESHSCPQQVPMPPGQEAQRVVCGIDSSMI 509
Query: 798 LSKSGAVFGWGKNTHGXLG 854
L+ G G N LG
Sbjct: 510 LTVPGQALACGSNRFNKLG 528
Score = 46.0 bits (104), Expect = 2e-04
Identities = 30/91 (32%), Positives = 43/91 (47%), Gaps = 6/91 (6%)
Frame = +3
Query: 600 VIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTISN--KEMSPQHISSLI----GVPI 761
V+QVA G +T SG L W A G G + ++ PQ IS + GV I
Sbjct: 334 VVQVAAGRTQKAGVTRSGRLILWEAPPLGAGGGSLLPGAVEQPQPQFISRFLEGQSGVTI 393
Query: 762 ALIACGNNHTFVLSKSGAVFGWGKNTHGXLG 854
+ACG+ T L+ G + +G ++G LG
Sbjct: 394 KHVACGDFFTACLTDRGIIMTFGSGSNGCLG 424
Score = 31.5 bits (68), Expect = 4.0
Identities = 14/56 (25%), Positives = 28/56 (50%)
Frame = +3
Query: 291 VAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIAC 458
VA G+ ++ + +YS G G+LGR+ E P ++ T+++++C
Sbjct: 618 VACGDAFTVAIGAESEVYSWGKGARGRLGRRDEDAGLPRPVQLDETHPYTVTSVSC 673
>BC004933-1|AAH04933.1| 351|Homo sapiens RCC2 protein protein.
Length = 351
Score = 86.6 bits (205), Expect = 1e-16
Identities = 61/194 (31%), Positives = 91/194 (46%), Gaps = 23/194 (11%)
Frame = +3
Query: 342 YSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDS 521
+S G N+ GQLG ++ + P L+E I + ACG H+LA+ E G F++G +
Sbjct: 1 WSWGRNEKGQLGHG-DTKRVEAPRLIEGLSHEVIVSAACGRNHTLALTETGSVFAFGENK 59
Query: 522 MGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLG 701
MGQLG A P + + + ++ACGA S+ + G+LYS+G YGQ G
Sbjct: 60 MGQLGLGNQTDAVPSPAQIM-YNGQPITKMACGAEFSMIMDCKGNLYSFGCPEYGQLGHN 118
Query: 702 TIS-----------NKEMSPQHISSLI------------GVPIALIACGNNHTFVLSKSG 812
+ + E+ P+ ++ I V + +ACG NHT VL
Sbjct: 119 SDGKFIARAQRIEYDCELVPRRVAIFIEKTKDGQILPVPNVVVRDVACGANHTLVLDSQK 178
Query: 813 AVFGWGKNTHGXLG 854
VF WG +G LG
Sbjct: 179 RVFSWGFGGYGRLG 192
Score = 84.2 bits (199), Expect = 5e-16
Identities = 71/241 (29%), Positives = 111/241 (46%), Gaps = 25/241 (10%)
Frame = +3
Query: 183 WGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNND 362
WG +L G T V P L + + I + A G H+L L+ +G +++ G N
Sbjct: 3 WGRNEKGQL---GHGDTKRVEAPRLIEGLSHEVIVSAACGRNHTLALTETGSVFAFGENK 59
Query: 363 VGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNN 542
+GQLG ++D +PA + + I+ +ACG + S+ +D G +S+G GQLG+N
Sbjct: 60 MGQLGLGNQTDAVPSPAQI-MYNGQPITKMACGAEFSMIMDCKGNLYSFGCPEYGQLGHN 118
Query: 543 LG----AHAQ-----------------DKPKFVKGLATKNVI--QVACGAYHSVALTNSG 653
A AQ +K K + L NV+ VACGA H++ L +
Sbjct: 119 SDGKFIARAQRIEYDCELVPRRVAIFIEKTKDGQILPVPNVVVRDVACGANHTLVLDSQK 178
Query: 654 DLYSWGANSYGQCGLGTISNKEMSPQHIS--SLIGVPIALIACGNNHTFVLSKSGAVFGW 827
++SWG YG+ G EM P+ + G + I G +F +S+ G +F W
Sbjct: 179 RVFSWGFGGYGRLGHAE-QKDEMVPRLVKLFDFPGRGASQIYAGYTCSFAVSEVGGLFFW 237
Query: 828 G 830
G
Sbjct: 238 G 238
Score = 64.5 bits (150), Expect = 5e-10
Identities = 70/255 (27%), Positives = 109/255 (42%), Gaps = 28/255 (10%)
Frame = +3
Query: 174 MFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCG 353
+F +G +L + G+Q TD V P + I +A G S+ + G+LYS G
Sbjct: 52 VFAFGENKMGQLGL-GNQ-TDAVPSPAQIMYN-GQPITKMACGAEFSMIMDCKGNLYSFG 108
Query: 354 NNDVGQLGRQT-----------ESDNGKNPALVETFKDCT------------ISTIACGL 464
+ GQLG + E D P V F + T + +ACG
Sbjct: 109 CPEYGQLGHNSDGKFIARAQRIEYDCELVPRRVAIFIEKTKDGQILPVPNVVVRDVACGA 168
Query: 465 QHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDK--PKFVK--GLATKNVIQVACGAYHS 632
H+L +D + FSWG G+LG+ A +D+ P+ VK + Q+ G S
Sbjct: 169 NHTLVLDSQKRVFSWGFGGYGRLGH---AEQKDEMVPRLVKLFDFPGRGASQIYAGYTCS 225
Query: 633 VALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFVLSKSG 812
A++ G L+ WGA + T M P+ + L G I +ACG + + +++
Sbjct: 226 FAVSEVGGLFFWGATN-------TSRESTMYPKAVQDLCGWRIRSLACGKS-SIIVAADE 277
Query: 813 AVFGWGKN-THGXLG 854
+ WG + T G LG
Sbjct: 278 STISWGPSPTFGELG 292
>BC112101-1|AAI12102.1| 979|Homo sapiens NIMA related kinase 9
protein.
Length = 979
Score = 86.2 bits (204), Expect = 1e-16
Identities = 58/194 (29%), Positives = 94/194 (48%), Gaps = 6/194 (3%)
Frame = +3
Query: 291 VAAGEFHSLYLSNSGHLYSC-----GNNDVGQLGRQTESDNGKNPALVETFKDCTISTIA 455
V AG H ++ LY+ G GQLG ++ + P VE + I ++
Sbjct: 374 VCAGNTHFAVVTVEKELYTWVNMQGGTKLHGQLGHGDKASY-RQPKHVEKLQGKAIRQVS 432
Query: 456 CGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQD-KPKFVKGLATKNVIQVACGAYHS 632
CG ++ + + GQ +++GSD G +G + A + +P + + V QV+CG H
Sbjct: 433 CGDDFTVCVTDEGQLYAFGSDYYGCMGVDKVAGPEVLEPMQLNFFLSNPVEQVSCGDNHV 492
Query: 633 VALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFVLSKSG 812
V LT + ++YSWG YG+ GL + +PQ + + I + CG + TF+L++SG
Sbjct: 493 VVLTRNKEVYSWGCGEYGRLGLDS-EEDYYTPQKVDVPKALIIVAVQCGCDGTFLLTQSG 551
Query: 813 AVFGWGKNTHGXLG 854
V G N LG
Sbjct: 552 KVLACGLNEFNKLG 565
Score = 84.2 bits (199), Expect = 5e-16
Identities = 47/160 (29%), Positives = 86/160 (53%), Gaps = 8/160 (5%)
Frame = +3
Query: 399 GKN-PALVETFKD-CTISTIACGLQHSLAIDEWGQPFSW-----GSDSMGQLGNNLGAHA 557
GK+ P ++ K C+ + G H + + ++W G+ GQLG+ A
Sbjct: 355 GKSTPQKLDVIKSGCSARQVCAGNTHFAVVTVEKELYTWVNMQGGTKLHGQLGHGDKASY 414
Query: 558 QDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTISNKE-MSPQH 734
+ +PK V+ L K + QV+CG +V +T+ G LY++G++ YG G+ ++ E + P
Sbjct: 415 R-QPKHVEKLQGKAIRQVSCGDDFTVCVTDEGQLYAFGSDYYGCMGVDKVAGPEVLEPMQ 473
Query: 735 ISSLIGVPIALIACGNNHTFVLSKSGAVFGWGKNTHGXLG 854
++ + P+ ++CG+NH VL+++ V+ WG +G LG
Sbjct: 474 LNFFLSNPVEQVSCGDNHVVVLTRNKEVYSWGCGEYGRLG 513
Score = 71.7 bits (168), Expect = 3e-12
Identities = 51/216 (23%), Positives = 94/216 (43%), Gaps = 12/216 (5%)
Frame = +3
Query: 240 VIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALV 419
V++P + S+ ++ V+ G+ H + L+ + +YS G + G+LG +E D P V
Sbjct: 468 VLEPMQLNFFLSNPVEQVSCGDNHVVVLTRNKEVYSWGCGEYGRLGLDSEEDY-YTPQKV 526
Query: 420 ETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNN------LGAHAQDKPKFV- 578
+ K I + CG + + + G+ + G + +LG N + A + +
Sbjct: 527 DVPKALIIVAVQCGCDGTFLLTQSGKVLACGLNEFNKLGLNQCMSGIINHEAYHEVPYTT 586
Query: 579 -----KGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISS 743
K L+ + +A G H+ A+ G L ++G N GQ G+G +
Sbjct: 587 SFTLAKQLSFYKIRTIAPGKTHTAAIDERGRLLTFGCNKCGQLGVGNYKKRLGINLLGGP 646
Query: 744 LIGVPIALIACGNNHTFVLSKSGAVFGWGKNTHGXL 851
L G + ++CG+ T + +F WG +G L
Sbjct: 647 LGGKQVIRVSCGDEFTIAATDDNHIFAWGNGGNGRL 682
Score = 56.8 bits (131), Expect = 9e-08
Identities = 54/195 (27%), Positives = 89/195 (45%), Gaps = 14/195 (7%)
Frame = +3
Query: 156 LQNYKKMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSG 335
L K+++ WG + L +D + K + K + I AV G + L+ SG
Sbjct: 495 LTRNKEVYSWGCGEYGRLGLDSEEDYYTPQKVDVPK---ALIIVAVQCGCDGTFLLTQSG 551
Query: 336 HLYSCGNNDVGQLG-RQTESDNGKNPA-----------LVETFKDCTISTIACGLQHSLA 479
+ +CG N+ +LG Q S + A L + I TIA G H+ A
Sbjct: 552 KVLACGLNEFNKLGLNQCMSGIINHEAYHEVPYTTSFTLAKQLSFYKIRTIAPGKTHTAA 611
Query: 480 IDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKG--LATKNVIQVACGAYHSVALTNSG 653
IDE G+ ++G + GQLG +G + + + G L K VI+V+CG ++A T+
Sbjct: 612 IDERGRLLTFGCNKCGQLG--VGNYKKRLGINLLGGPLGGKQVIRVSCGDEFTIAATDDN 669
Query: 654 DLYSWGANSYGQCGL 698
+++WG G+ +
Sbjct: 670 HIFAWGNGGNGRLAM 684
>BC093881-1|AAH93881.1| 979|Homo sapiens NIMA (never in mitosis
gene a)- related kinase 9 protein.
Length = 979
Score = 86.2 bits (204), Expect = 1e-16
Identities = 58/194 (29%), Positives = 94/194 (48%), Gaps = 6/194 (3%)
Frame = +3
Query: 291 VAAGEFHSLYLSNSGHLYSC-----GNNDVGQLGRQTESDNGKNPALVETFKDCTISTIA 455
V AG H ++ LY+ G GQLG ++ + P VE + I ++
Sbjct: 374 VCAGNTHFAVVTVEKELYTWVNMQGGTKLHGQLGHGDKASY-RQPKHVEKLQGKAIRQVS 432
Query: 456 CGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQD-KPKFVKGLATKNVIQVACGAYHS 632
CG ++ + + GQ +++GSD G +G + A + +P + + V QV+CG H
Sbjct: 433 CGDDFTVCVTDEGQLYAFGSDYYGCMGVDKVAGPEVLEPMQLNFFLSNPVEQVSCGDNHV 492
Query: 633 VALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFVLSKSG 812
V LT + ++YSWG YG+ GL + +PQ + + I + CG + TF+L++SG
Sbjct: 493 VVLTRNKEVYSWGCGEYGRLGLDS-EEDYYTPQKVDVPKALIIVAVQCGCDGTFLLTQSG 551
Query: 813 AVFGWGKNTHGXLG 854
V G N LG
Sbjct: 552 KVLACGLNEFNKLG 565
Score = 84.2 bits (199), Expect = 5e-16
Identities = 47/160 (29%), Positives = 86/160 (53%), Gaps = 8/160 (5%)
Frame = +3
Query: 399 GKN-PALVETFKD-CTISTIACGLQHSLAIDEWGQPFSW-----GSDSMGQLGNNLGAHA 557
GK+ P ++ K C+ + G H + + ++W G+ GQLG+ A
Sbjct: 355 GKSTPQKLDVIKSGCSARQVCAGNTHFAVVTVEKELYTWVNMQGGTKLHGQLGHGDKASY 414
Query: 558 QDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTISNKE-MSPQH 734
+ +PK V+ L K + QV+CG +V +T+ G LY++G++ YG G+ ++ E + P
Sbjct: 415 R-QPKHVEKLQGKAIRQVSCGDDFTVCVTDEGQLYAFGSDYYGCMGVDKVAGPEVLEPMQ 473
Query: 735 ISSLIGVPIALIACGNNHTFVLSKSGAVFGWGKNTHGXLG 854
++ + P+ ++CG+NH VL+++ V+ WG +G LG
Sbjct: 474 LNFFLSNPVEQVSCGDNHVVVLTRNKEVYSWGCGEYGRLG 513
Score = 71.7 bits (168), Expect = 3e-12
Identities = 51/216 (23%), Positives = 94/216 (43%), Gaps = 12/216 (5%)
Frame = +3
Query: 240 VIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALV 419
V++P + S+ ++ V+ G+ H + L+ + +YS G + G+LG +E D P V
Sbjct: 468 VLEPMQLNFFLSNPVEQVSCGDNHVVVLTRNKEVYSWGCGEYGRLGLDSEEDY-YTPQKV 526
Query: 420 ETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNN------LGAHAQDKPKFV- 578
+ K I + CG + + + G+ + G + +LG N + A + +
Sbjct: 527 DVPKALIIVAVQCGCDGTFLLTQSGKVLACGLNEFNKLGLNQCMSGIINHEAYHEVPYTT 586
Query: 579 -----KGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISS 743
K L+ + +A G H+ A+ G L ++G N GQ G+G +
Sbjct: 587 SFTLAKQLSFYKIRTIAPGKTHTAAIDERGRLLTFGCNKCGQLGVGNYKKRLGINLLGGP 646
Query: 744 LIGVPIALIACGNNHTFVLSKSGAVFGWGKNTHGXL 851
L G + ++CG+ T + +F WG +G L
Sbjct: 647 LGGKQVIRVSCGDEFTIAATDDNHIFAWGNGGNGRL 682
Score = 56.8 bits (131), Expect = 9e-08
Identities = 54/195 (27%), Positives = 89/195 (45%), Gaps = 14/195 (7%)
Frame = +3
Query: 156 LQNYKKMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSG 335
L K+++ WG + L +D + K + K + I AV G + L+ SG
Sbjct: 495 LTRNKEVYSWGCGEYGRLGLDSEEDYYTPQKVDVPK---ALIIVAVQCGCDGTFLLTQSG 551
Query: 336 HLYSCGNNDVGQLG-RQTESDNGKNPA-----------LVETFKDCTISTIACGLQHSLA 479
+ +CG N+ +LG Q S + A L + I TIA G H+ A
Sbjct: 552 KVLACGLNEFNKLGLNQCMSGIINHEAYHEVPYTTSFTLAKQLSFYKIRTIAPGKTHTAA 611
Query: 480 IDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKG--LATKNVIQVACGAYHSVALTNSG 653
IDE G+ ++G + GQLG +G + + + G L K VI+V+CG ++A T+
Sbjct: 612 IDERGRLLTFGCNKCGQLG--VGNYKKRLGINLLGGPLGGKQVIRVSCGDEFTIAATDDN 669
Query: 654 DLYSWGANSYGQCGL 698
+++WG G+ +
Sbjct: 670 HIFAWGNGGNGRLAM 684
>AY080896-1|AAL87410.1| 979|Homo sapiens NIMA-family kinase NERCC1
protein.
Length = 979
Score = 86.2 bits (204), Expect = 1e-16
Identities = 58/194 (29%), Positives = 94/194 (48%), Gaps = 6/194 (3%)
Frame = +3
Query: 291 VAAGEFHSLYLSNSGHLYSC-----GNNDVGQLGRQTESDNGKNPALVETFKDCTISTIA 455
V AG H ++ LY+ G GQLG ++ + P VE + I ++
Sbjct: 374 VCAGNTHFAVVTVEKELYTWVNMQGGTKLHGQLGHGDKASY-RQPKHVEKLQGKAIHQVS 432
Query: 456 CGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQD-KPKFVKGLATKNVIQVACGAYHS 632
CG ++ + + GQ +++GSD G +G + A + +P + + V QV+CG H
Sbjct: 433 CGDDFTVCVTDEGQLYAFGSDYYGCMGVDKVAGPEVLEPMQLNFFLSNPVEQVSCGDNHV 492
Query: 633 VALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFVLSKSG 812
V LT + ++YSWG YG+ GL + +PQ + + I + CG + TF+L++SG
Sbjct: 493 VVLTRNKEVYSWGCGEYGRLGLDS-EEDYYTPQKVDVPKALIIVAVQCGCDGTFLLTQSG 551
Query: 813 AVFGWGKNTHGXLG 854
V G N LG
Sbjct: 552 KVLACGLNEFNKLG 565
Score = 84.2 bits (199), Expect = 5e-16
Identities = 47/160 (29%), Positives = 86/160 (53%), Gaps = 8/160 (5%)
Frame = +3
Query: 399 GKN-PALVETFKD-CTISTIACGLQHSLAIDEWGQPFSW-----GSDSMGQLGNNLGAHA 557
GK+ P ++ K C+ + G H + + ++W G+ GQLG+ A
Sbjct: 355 GKSTPQKLDVIKSGCSARQVCAGNTHFAVVTVEKELYTWVNMQGGTKLHGQLGHGDKASY 414
Query: 558 QDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTISNKE-MSPQH 734
+ +PK V+ L K + QV+CG +V +T+ G LY++G++ YG G+ ++ E + P
Sbjct: 415 R-QPKHVEKLQGKAIHQVSCGDDFTVCVTDEGQLYAFGSDYYGCMGVDKVAGPEVLEPMQ 473
Query: 735 ISSLIGVPIALIACGNNHTFVLSKSGAVFGWGKNTHGXLG 854
++ + P+ ++CG+NH VL+++ V+ WG +G LG
Sbjct: 474 LNFFLSNPVEQVSCGDNHVVVLTRNKEVYSWGCGEYGRLG 513
Score = 71.7 bits (168), Expect = 3e-12
Identities = 51/216 (23%), Positives = 94/216 (43%), Gaps = 12/216 (5%)
Frame = +3
Query: 240 VIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALV 419
V++P + S+ ++ V+ G+ H + L+ + +YS G + G+LG +E D P V
Sbjct: 468 VLEPMQLNFFLSNPVEQVSCGDNHVVVLTRNKEVYSWGCGEYGRLGLDSEEDY-YTPQKV 526
Query: 420 ETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNN------LGAHAQDKPKFV- 578
+ K I + CG + + + G+ + G + +LG N + A + +
Sbjct: 527 DVPKALIIVAVQCGCDGTFLLTQSGKVLACGLNEFNKLGLNQCMSGIINHEAYHEVPYTT 586
Query: 579 -----KGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISS 743
K L+ + +A G H+ A+ G L ++G N GQ G+G +
Sbjct: 587 SFTLAKQLSFYKIRTIAPGKTHTAAIDERGRLLTFGCNKCGQLGVGNYKKRLGINLLGGP 646
Query: 744 LIGVPIALIACGNNHTFVLSKSGAVFGWGKNTHGXL 851
L G + ++CG+ T + +F WG +G L
Sbjct: 647 LGGKQVIRVSCGDEFTIAATDDNHIFAWGNGGNGRL 682
Score = 56.8 bits (131), Expect = 9e-08
Identities = 54/195 (27%), Positives = 89/195 (45%), Gaps = 14/195 (7%)
Frame = +3
Query: 156 LQNYKKMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSG 335
L K+++ WG + L +D + K + K + I AV G + L+ SG
Sbjct: 495 LTRNKEVYSWGCGEYGRLGLDSEEDYYTPQKVDVPK---ALIIVAVQCGCDGTFLLTQSG 551
Query: 336 HLYSCGNNDVGQLG-RQTESDNGKNPA-----------LVETFKDCTISTIACGLQHSLA 479
+ +CG N+ +LG Q S + A L + I TIA G H+ A
Sbjct: 552 KVLACGLNEFNKLGLNQCMSGIINHEAYHEVPYTTSFTLAKQLSFYKIRTIAPGKTHTAA 611
Query: 480 IDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKG--LATKNVIQVACGAYHSVALTNSG 653
IDE G+ ++G + GQLG +G + + + G L K VI+V+CG ++A T+
Sbjct: 612 IDERGRLLTFGCNKCGQLG--VGNYKKRLGINLLGGPLGGKQVIRVSCGDEFTIAATDDN 669
Query: 654 DLYSWGANSYGQCGL 698
+++WG G+ +
Sbjct: 670 HIFAWGNGGNGRLAM 684
>AY048580-1|AAL05428.1| 979|Homo sapiens NIMA-related kinase Nek8
protein.
Length = 979
Score = 86.2 bits (204), Expect = 1e-16
Identities = 58/194 (29%), Positives = 94/194 (48%), Gaps = 6/194 (3%)
Frame = +3
Query: 291 VAAGEFHSLYLSNSGHLYSC-----GNNDVGQLGRQTESDNGKNPALVETFKDCTISTIA 455
V AG H ++ LY+ G GQLG ++ + P VE + I ++
Sbjct: 374 VCAGNTHFAVVTVEKELYTWVNMQGGTKLHGQLGHGDKASY-RQPKHVEKLQGKAIHQVS 432
Query: 456 CGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQD-KPKFVKGLATKNVIQVACGAYHS 632
CG ++ + + GQ +++GSD G +G + A + +P + + V QV+CG H
Sbjct: 433 CGDDFTVCVTDEGQLYAFGSDYYGCMGVDKVAGPEVLEPMQLNFFLSNPVEQVSCGDNHV 492
Query: 633 VALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFVLSKSG 812
V LT + ++YSWG YG+ GL + +PQ + + I + CG + TF+L++SG
Sbjct: 493 VVLTRNKEVYSWGCGEYGRLGLDS-EEDYYTPQKVDVPKALIIVAVQCGCDGTFLLTQSG 551
Query: 813 AVFGWGKNTHGXLG 854
V G N LG
Sbjct: 552 KVLACGLNEFNKLG 565
Score = 84.2 bits (199), Expect = 5e-16
Identities = 47/160 (29%), Positives = 86/160 (53%), Gaps = 8/160 (5%)
Frame = +3
Query: 399 GKN-PALVETFKD-CTISTIACGLQHSLAIDEWGQPFSW-----GSDSMGQLGNNLGAHA 557
GK+ P ++ K C+ + G H + + ++W G+ GQLG+ A
Sbjct: 355 GKSTPQKLDVIKSGCSARQVCAGNTHFAVVTVEKELYTWVNMQGGTKLHGQLGHGDKASY 414
Query: 558 QDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTISNKE-MSPQH 734
+ +PK V+ L K + QV+CG +V +T+ G LY++G++ YG G+ ++ E + P
Sbjct: 415 R-QPKHVEKLQGKAIHQVSCGDDFTVCVTDEGQLYAFGSDYYGCMGVDKVAGPEVLEPMQ 473
Query: 735 ISSLIGVPIALIACGNNHTFVLSKSGAVFGWGKNTHGXLG 854
++ + P+ ++CG+NH VL+++ V+ WG +G LG
Sbjct: 474 LNFFLSNPVEQVSCGDNHVVVLTRNKEVYSWGCGEYGRLG 513
Score = 71.7 bits (168), Expect = 3e-12
Identities = 51/216 (23%), Positives = 94/216 (43%), Gaps = 12/216 (5%)
Frame = +3
Query: 240 VIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALV 419
V++P + S+ ++ V+ G+ H + L+ + +YS G + G+LG +E D P V
Sbjct: 468 VLEPMQLNFFLSNPVEQVSCGDNHVVVLTRNKEVYSWGCGEYGRLGLDSEEDY-YTPQKV 526
Query: 420 ETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNN------LGAHAQDKPKFV- 578
+ K I + CG + + + G+ + G + +LG N + A + +
Sbjct: 527 DVPKALIIVAVQCGCDGTFLLTQSGKVLACGLNEFNKLGLNQCMSGIINHEAYHEVPYTT 586
Query: 579 -----KGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISS 743
K L+ + +A G H+ A+ G L ++G N GQ G+G +
Sbjct: 587 SFTLAKQLSFYKIRTIAPGKTHTAAIDERGRLLTFGCNKCGQLGVGNYKKRLGINLLGGP 646
Query: 744 LIGVPIALIACGNNHTFVLSKSGAVFGWGKNTHGXL 851
L G + ++CG+ T + +F WG +G L
Sbjct: 647 LGGKQVIRVSCGDEFTIAATDDNHIFAWGNGGNGRL 682
Score = 56.8 bits (131), Expect = 9e-08
Identities = 54/195 (27%), Positives = 89/195 (45%), Gaps = 14/195 (7%)
Frame = +3
Query: 156 LQNYKKMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSG 335
L K+++ WG + L +D + K + K + I AV G + L+ SG
Sbjct: 495 LTRNKEVYSWGCGEYGRLGLDSEEDYYTPQKVDVPK---ALIIVAVQCGCDGTFLLTQSG 551
Query: 336 HLYSCGNNDVGQLG-RQTESDNGKNPA-----------LVETFKDCTISTIACGLQHSLA 479
+ +CG N+ +LG Q S + A L + I TIA G H+ A
Sbjct: 552 KVLACGLNEFNKLGLNQCMSGIINHEAYHEVPYTTSFTLAKQLSFYKIRTIAPGKTHTAA 611
Query: 480 IDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKG--LATKNVIQVACGAYHSVALTNSG 653
IDE G+ ++G + GQLG +G + + + G L K VI+V+CG ++A T+
Sbjct: 612 IDERGRLLTFGCNKCGQLG--VGNYKKRLGINLLGGPLGGKQVIRVSCGDEFTIAATDDN 669
Query: 654 DLYSWGANSYGQCGL 698
+++WG G+ +
Sbjct: 670 HIFAWGNGGNGRLAM 684
>AC007055-4|AAD31939.1| 414|Homo sapiens protein ( Homo sapiens
chromosome 14 clone BAC 201F1 map 14q24.3, complete
sequence. ).
Length = 414
Score = 86.2 bits (204), Expect = 1e-16
Identities = 58/194 (29%), Positives = 94/194 (48%), Gaps = 6/194 (3%)
Frame = +3
Query: 291 VAAGEFHSLYLSNSGHLYSC-----GNNDVGQLGRQTESDNGKNPALVETFKDCTISTIA 455
V AG H ++ LY+ G GQLG ++ + P VE + I ++
Sbjct: 44 VCAGNTHFAVVTVEKELYTWVNMQGGTKLHGQLGHGDKASY-RQPKHVEKLQGKAIRQVS 102
Query: 456 CGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQD-KPKFVKGLATKNVIQVACGAYHS 632
CG ++ + + GQ +++GSD G +G + A + +P + + V QV+CG H
Sbjct: 103 CGDDFTVCVTDEGQLYAFGSDYYGCMGVDKVAGPEVLEPMQLNFFLSNPVEQVSCGDNHV 162
Query: 633 VALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFVLSKSG 812
V LT + ++YSWG YG+ GL + +PQ + + I + CG + TF+L++SG
Sbjct: 163 VVLTRNKEVYSWGCGEYGRLGLDS-EEDYYTPQKVDVPKALIIVAVQCGCDGTFLLTQSG 221
Query: 813 AVFGWGKNTHGXLG 854
V G N LG
Sbjct: 222 KVLACGLNEFNKLG 235
Score = 84.2 bits (199), Expect = 5e-16
Identities = 47/160 (29%), Positives = 86/160 (53%), Gaps = 8/160 (5%)
Frame = +3
Query: 399 GKN-PALVETFKD-CTISTIACGLQHSLAIDEWGQPFSW-----GSDSMGQLGNNLGAHA 557
GK+ P ++ K C+ + G H + + ++W G+ GQLG+ A
Sbjct: 25 GKSTPQKLDVIKSGCSARQVCAGNTHFAVVTVEKELYTWVNMQGGTKLHGQLGHGDKASY 84
Query: 558 QDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTISNKE-MSPQH 734
+ +PK V+ L K + QV+CG +V +T+ G LY++G++ YG G+ ++ E + P
Sbjct: 85 R-QPKHVEKLQGKAIRQVSCGDDFTVCVTDEGQLYAFGSDYYGCMGVDKVAGPEVLEPMQ 143
Query: 735 ISSLIGVPIALIACGNNHTFVLSKSGAVFGWGKNTHGXLG 854
++ + P+ ++CG+NH VL+++ V+ WG +G LG
Sbjct: 144 LNFFLSNPVEQVSCGDNHVVVLTRNKEVYSWGCGEYGRLG 183
Score = 71.7 bits (168), Expect = 3e-12
Identities = 51/216 (23%), Positives = 94/216 (43%), Gaps = 12/216 (5%)
Frame = +3
Query: 240 VIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALV 419
V++P + S+ ++ V+ G+ H + L+ + +YS G + G+LG +E D P V
Sbjct: 138 VLEPMQLNFFLSNPVEQVSCGDNHVVVLTRNKEVYSWGCGEYGRLGLDSEEDY-YTPQKV 196
Query: 420 ETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNN------LGAHAQDKPKFV- 578
+ K I + CG + + + G+ + G + +LG N + A + +
Sbjct: 197 DVPKALIIVAVQCGCDGTFLLTQSGKVLACGLNEFNKLGLNQCMSGIINHEAYHEVPYTT 256
Query: 579 -----KGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISS 743
K L+ + +A G H+ A+ G L ++G N GQ G+G +
Sbjct: 257 SFTLAKQLSFYKIRTIAPGKTHTAAIDERGRLLTFGCNKCGQLGVGNYKKRLGINLLGGP 316
Query: 744 LIGVPIALIACGNNHTFVLSKSGAVFGWGKNTHGXL 851
L G + ++CG+ T + +F WG +G L
Sbjct: 317 LGGKQVIRVSCGDEFTIAATDDNHIFAWGNGGNGRL 352
Score = 56.8 bits (131), Expect = 9e-08
Identities = 54/195 (27%), Positives = 89/195 (45%), Gaps = 14/195 (7%)
Frame = +3
Query: 156 LQNYKKMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSG 335
L K+++ WG + L +D + K + K + I AV G + L+ SG
Sbjct: 165 LTRNKEVYSWGCGEYGRLGLDSEEDYYTPQKVDVPK---ALIIVAVQCGCDGTFLLTQSG 221
Query: 336 HLYSCGNNDVGQLG-RQTESDNGKNPA-----------LVETFKDCTISTIACGLQHSLA 479
+ +CG N+ +LG Q S + A L + I TIA G H+ A
Sbjct: 222 KVLACGLNEFNKLGLNQCMSGIINHEAYHEVPYTTSFTLAKQLSFYKIRTIAPGKTHTAA 281
Query: 480 IDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKG--LATKNVIQVACGAYHSVALTNSG 653
IDE G+ ++G + GQLG +G + + + G L K VI+V+CG ++A T+
Sbjct: 282 IDERGRLLTFGCNKCGQLG--VGNYKKRLGINLLGGPLGGKQVIRVSCGDEFTIAATDDN 339
Query: 654 DLYSWGANSYGQCGL 698
+++WG G+ +
Sbjct: 340 HIFAWGNGGNGRLAM 354
>AB082526-1|BAC02704.1| 1011|Homo sapiens KIAA1995 protein protein.
Length = 1011
Score = 86.2 bits (204), Expect = 1e-16
Identities = 58/194 (29%), Positives = 94/194 (48%), Gaps = 6/194 (3%)
Frame = +3
Query: 291 VAAGEFHSLYLSNSGHLYSC-----GNNDVGQLGRQTESDNGKNPALVETFKDCTISTIA 455
V AG H ++ LY+ G GQLG ++ + P VE + I ++
Sbjct: 406 VCAGNTHFAVVTVEKELYTWVNMQGGTKLHGQLGHGDKASY-RQPKHVEKLQGKAIHQVS 464
Query: 456 CGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQD-KPKFVKGLATKNVIQVACGAYHS 632
CG ++ + + GQ +++GSD G +G + A + +P + + V QV+CG H
Sbjct: 465 CGDDFTVCVTDEGQLYAFGSDYYGCMGVDKVAGPEVLEPMQLNFFLSNPVEQVSCGDNHV 524
Query: 633 VALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFVLSKSG 812
V LT + ++YSWG YG+ GL + +PQ + + I + CG + TF+L++SG
Sbjct: 525 VVLTRNKEVYSWGCGEYGRLGLDS-EEDYYTPQKVDVPKALIIVAVQCGCDGTFLLTQSG 583
Query: 813 AVFGWGKNTHGXLG 854
V G N LG
Sbjct: 584 KVLACGLNEFNKLG 597
Score = 84.2 bits (199), Expect = 5e-16
Identities = 47/160 (29%), Positives = 86/160 (53%), Gaps = 8/160 (5%)
Frame = +3
Query: 399 GKN-PALVETFKD-CTISTIACGLQHSLAIDEWGQPFSW-----GSDSMGQLGNNLGAHA 557
GK+ P ++ K C+ + G H + + ++W G+ GQLG+ A
Sbjct: 387 GKSTPQKLDVIKSGCSARQVCAGNTHFAVVTVEKELYTWVNMQGGTKLHGQLGHGDKASY 446
Query: 558 QDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTISNKE-MSPQH 734
+ +PK V+ L K + QV+CG +V +T+ G LY++G++ YG G+ ++ E + P
Sbjct: 447 R-QPKHVEKLQGKAIHQVSCGDDFTVCVTDEGQLYAFGSDYYGCMGVDKVAGPEVLEPMQ 505
Query: 735 ISSLIGVPIALIACGNNHTFVLSKSGAVFGWGKNTHGXLG 854
++ + P+ ++CG+NH VL+++ V+ WG +G LG
Sbjct: 506 LNFFLSNPVEQVSCGDNHVVVLTRNKEVYSWGCGEYGRLG 545
Score = 71.7 bits (168), Expect = 3e-12
Identities = 51/216 (23%), Positives = 94/216 (43%), Gaps = 12/216 (5%)
Frame = +3
Query: 240 VIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALV 419
V++P + S+ ++ V+ G+ H + L+ + +YS G + G+LG +E D P V
Sbjct: 500 VLEPMQLNFFLSNPVEQVSCGDNHVVVLTRNKEVYSWGCGEYGRLGLDSEEDY-YTPQKV 558
Query: 420 ETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNN------LGAHAQDKPKFV- 578
+ K I + CG + + + G+ + G + +LG N + A + +
Sbjct: 559 DVPKALIIVAVQCGCDGTFLLTQSGKVLACGLNEFNKLGLNQCMSGIINHEAYHEVPYTT 618
Query: 579 -----KGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISS 743
K L+ + +A G H+ A+ G L ++G N GQ G+G +
Sbjct: 619 SFTLAKQLSFYKIRTIAPGKTHTAAIDERGRLLTFGCNKCGQLGVGNYKKRLGINLLGGP 678
Query: 744 LIGVPIALIACGNNHTFVLSKSGAVFGWGKNTHGXL 851
L G + ++CG+ T + +F WG +G L
Sbjct: 679 LGGKQVIRVSCGDEFTIAATDDNHIFAWGNGGNGRL 714
Score = 56.8 bits (131), Expect = 9e-08
Identities = 54/195 (27%), Positives = 89/195 (45%), Gaps = 14/195 (7%)
Frame = +3
Query: 156 LQNYKKMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSG 335
L K+++ WG + L +D + K + K + I AV G + L+ SG
Sbjct: 527 LTRNKEVYSWGCGEYGRLGLDSEEDYYTPQKVDVPK---ALIIVAVQCGCDGTFLLTQSG 583
Query: 336 HLYSCGNNDVGQLG-RQTESDNGKNPA-----------LVETFKDCTISTIACGLQHSLA 479
+ +CG N+ +LG Q S + A L + I TIA G H+ A
Sbjct: 584 KVLACGLNEFNKLGLNQCMSGIINHEAYHEVPYTTSFTLAKQLSFYKIRTIAPGKTHTAA 643
Query: 480 IDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKG--LATKNVIQVACGAYHSVALTNSG 653
IDE G+ ++G + GQLG +G + + + G L K VI+V+CG ++A T+
Sbjct: 644 IDERGRLLTFGCNKCGQLG--VGNYKKRLGINLLGGPLGGKQVIRVSCGDEFTIAATDDN 701
Query: 654 DLYSWGANSYGQCGL 698
+++WG G+ +
Sbjct: 702 HIFAWGNGGNGRLAM 716
>X12654-1|CAA31182.1| 421|Homo sapiens protein ( Human mRNA for
cell cycle gene RCC1. ).
Length = 421
Score = 85.0 bits (201), Expect = 3e-16
Identities = 55/184 (29%), Positives = 88/184 (47%), Gaps = 2/184 (1%)
Frame = +3
Query: 309 HSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDE 488
H + + G + + G DVGQLG K PALV +D + G H++ + +
Sbjct: 27 HRSHSTEPGLVLTLGQGDVGQLGLGENVMERKKPALVSIPED--VVQAEAGGMHTVCLSK 84
Query: 489 WGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 668
GQ +S+G + G LG + + L K V+QV+ G H+ ALT+ G ++ W
Sbjct: 85 SGQVYSFGCNDEGALGRDTSVEGSEMVPGKVELQEK-VVQVSAGDSHTAALTDDGRVFLW 143
Query: 669 GA--NSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFVLSKSGAVFGWGKNTH 842
G+ ++ G GL K M P + + VP+ +A GN+H +L+ G ++ G
Sbjct: 144 GSFRDNNGVIGLLEPMKKSMVPVQVQ--LDVPVVKVASGNDHLVMLTADGDLYTLGCGEQ 201
Query: 843 GXLG 854
G LG
Sbjct: 202 GQLG 205
Score = 76.6 bits (180), Expect = 1e-13
Identities = 60/205 (29%), Positives = 94/205 (45%), Gaps = 17/205 (8%)
Frame = +3
Query: 291 VAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTE--SDNGKNPALVETF-KDCTI------ 443
VA+G H + L+ G LY+ G + GQLGR E ++ G L C +
Sbjct: 177 VASGNDHLVMLTADGDLYTLGCGEQGQLGRVPELFANRGGRQGLERLLVPKCVMLKSRGS 236
Query: 444 ------STIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGL--ATKN 599
CG + AI G + +G + QLG G + P+ + +TK+
Sbjct: 237 RGHVRFQDAFCGAYFTFAISHEGHVYGFGLSNYHQLGTP-GTESCFIPQNLTSFKNSTKS 295
Query: 600 VIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACG 779
+ + G +H+V + + G YS G YG+ GLG + ++ P IS L V + +ACG
Sbjct: 296 WVGFSGGQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPAV--SSVACG 353
Query: 780 NNHTFVLSKSGAVFGWGKNTHGXLG 854
+ + ++K G VF WG T+ LG
Sbjct: 354 ASVGYAVTKDGRVFAWGMGTNYQLG 378
Score = 75.4 bits (177), Expect = 3e-13
Identities = 71/222 (31%), Positives = 103/222 (46%), Gaps = 19/222 (8%)
Frame = +3
Query: 246 KPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKN-PALVE 422
KP L E D +QA A G H++ LS SG +YS G ND G LGR T + + P VE
Sbjct: 59 KPALVSIPE-DVVQAEAGG-MHTVCLSKSGQVYSFGCNDEGALGRDTSVEGSEMVPGKVE 116
Query: 423 TFKDCTISTIACGLQHSLAIDEWGQPFSWGS--DSMGQLGNNLGAHAQDKPKFVKGLATK 596
+ + ++ G H+ A+ + G+ F WGS D+ G +G L + V+
Sbjct: 117 LQE--KVVQVSAGDSHTAALTDDGRVFLWGSFRDNNGVIG--LLEPMKKSMVPVQVQLDV 172
Query: 597 NVIQVACGAYHSVALTNSGDLYSWGANSYGQCG-LGTISNKEMSPQHISSLIGVPIALIA 773
V++VA G H V LT GDLY+ G GQ G + + Q + L+ VP ++
Sbjct: 173 PVVKVASGNDHLVMLTADGDLYTLGCGEQGQLGRVPELFANRGGRQGLERLL-VPKCVML 231
Query: 774 ---------------CGNNHTFVLSKSGAVFGWGKNTHGXLG 854
CG TF +S G V+G+G + + LG
Sbjct: 232 KSRGSRGHVRFQDAFCGAYFTFAISHEGHVYGFGLSNYHQLG 273
Score = 68.9 bits (161), Expect = 2e-11
Identities = 48/177 (27%), Positives = 83/177 (46%), Gaps = 3/177 (1%)
Frame = +3
Query: 285 QAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIAC-- 458
Q G + + +S+ GH+Y G ++ QLG +++ P + +FK+ T S +
Sbjct: 243 QDAFCGAYFTFAISHEGHVYGFGLSNYHQLGTPG-TESCFIPQNLTSFKNSTKSWVGFSG 301
Query: 459 GLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVA 638
G H++ +D G+ +S G G+LG GA + P + L V VACGA A
Sbjct: 302 GQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPA--VSSVACGASVGYA 359
Query: 639 LTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIAL-IACGNNHTFVLSK 806
+T G +++WG + Q G G + + + + + L ++ G HT +L K
Sbjct: 360 VTKDGRVFAWGMGTNYQLGTGQDEDAWSPVEMMGKQLENRVVLSVSSGGQHTVLLVK 416
>X06130-1|CAA29496.1| 421|Homo sapiens protein ( Human mRNA for
cell cycle gene RCC1. ).
Length = 421
Score = 85.0 bits (201), Expect = 3e-16
Identities = 55/184 (29%), Positives = 88/184 (47%), Gaps = 2/184 (1%)
Frame = +3
Query: 309 HSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDE 488
H + + G + + G DVGQLG K PALV +D + G H++ + +
Sbjct: 27 HRSHSTEPGLVLTLGQGDVGQLGLGENVMERKKPALVSIPED--VVQAEAGGMHTVCLSK 84
Query: 489 WGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 668
GQ +S+G + G LG + + L K V+QV+ G H+ ALT+ G ++ W
Sbjct: 85 SGQVYSFGCNDEGALGRDTSVEGSEMVPGKVELQEK-VVQVSAGDSHTAALTDDGRVFLW 143
Query: 669 GA--NSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFVLSKSGAVFGWGKNTH 842
G+ ++ G GL K M P + + VP+ +A GN+H +L+ G ++ G
Sbjct: 144 GSFRDNNGVIGLLEPMKKSMVPVQVQ--LDVPVVKVASGNDHLVMLTADGDLYTLGCGEQ 201
Query: 843 GXLG 854
G LG
Sbjct: 202 GQLG 205
Score = 76.6 bits (180), Expect = 1e-13
Identities = 60/205 (29%), Positives = 94/205 (45%), Gaps = 17/205 (8%)
Frame = +3
Query: 291 VAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTE--SDNGKNPALVETF-KDCTI------ 443
VA+G H + L+ G LY+ G + GQLGR E ++ G L C +
Sbjct: 177 VASGNDHLVMLTADGDLYTLGCGEQGQLGRVPELFANRGGRQGLERLLVPKCVMLKSRGS 236
Query: 444 ------STIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGL--ATKN 599
CG + AI G + +G + QLG G + P+ + +TK+
Sbjct: 237 RGHVRFQDAFCGAYFTFAISHEGHVYGFGLSNYHQLGTP-GTESCFIPQNLTSFKNSTKS 295
Query: 600 VIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACG 779
+ + G +H+V + + G YS G YG+ GLG + ++ P IS L V + +ACG
Sbjct: 296 WVGFSGGQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPAV--SSVACG 353
Query: 780 NNHTFVLSKSGAVFGWGKNTHGXLG 854
+ + ++K G VF WG T+ LG
Sbjct: 354 ASVGYAVTKDGRVFAWGMGTNYQLG 378
Score = 75.4 bits (177), Expect = 3e-13
Identities = 71/222 (31%), Positives = 103/222 (46%), Gaps = 19/222 (8%)
Frame = +3
Query: 246 KPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKN-PALVE 422
KP L E D +QA A G H++ LS SG +YS G ND G LGR T + + P VE
Sbjct: 59 KPALVSIPE-DVVQAEAGG-MHTVCLSKSGQVYSFGCNDEGALGRDTSVEGSEMVPGKVE 116
Query: 423 TFKDCTISTIACGLQHSLAIDEWGQPFSWGS--DSMGQLGNNLGAHAQDKPKFVKGLATK 596
+ + ++ G H+ A+ + G+ F WGS D+ G +G L + V+
Sbjct: 117 LQE--KVVQVSAGDSHTAALTDDGRVFLWGSFRDNNGVIG--LLEPMKKSMVPVQVQLDV 172
Query: 597 NVIQVACGAYHSVALTNSGDLYSWGANSYGQCG-LGTISNKEMSPQHISSLIGVPIALIA 773
V++VA G H V LT GDLY+ G GQ G + + Q + L+ VP ++
Sbjct: 173 PVVKVASGNDHLVMLTADGDLYTLGCGEQGQLGRVPELFANRGGRQGLERLL-VPKCVML 231
Query: 774 ---------------CGNNHTFVLSKSGAVFGWGKNTHGXLG 854
CG TF +S G V+G+G + + LG
Sbjct: 232 KSRGSRGHVRFQDAFCGAYFTFAISHEGHVYGFGLSNYHQLG 273
Score = 68.9 bits (161), Expect = 2e-11
Identities = 48/177 (27%), Positives = 83/177 (46%), Gaps = 3/177 (1%)
Frame = +3
Query: 285 QAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIAC-- 458
Q G + + +S+ GH+Y G ++ QLG +++ P + +FK+ T S +
Sbjct: 243 QDAFCGAYFTFAISHEGHVYGFGLSNYHQLGTPG-TESCFIPQNLTSFKNSTKSWVGFSG 301
Query: 459 GLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVA 638
G H++ +D G+ +S G G+LG GA + P + L V VACGA A
Sbjct: 302 GQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPA--VSSVACGASVGYA 359
Query: 639 LTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIAL-IACGNNHTFVLSK 806
+T G +++WG + Q G G + + + + + L ++ G HT +L K
Sbjct: 360 VTKDGRVFAWGMGTNYQLGTGQDEDAWSPVEMMGKQLENRVVLSVSSGGQHTVLLVK 416
>D00591-1|BAA00469.1| 421|Homo sapiens RCC1 protein.
Length = 421
Score = 85.0 bits (201), Expect = 3e-16
Identities = 55/184 (29%), Positives = 88/184 (47%), Gaps = 2/184 (1%)
Frame = +3
Query: 309 HSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDE 488
H + + G + + G DVGQLG K PALV +D + G H++ + +
Sbjct: 27 HRSHSTEPGLVLTLGQGDVGQLGLGENVMERKKPALVSIPED--VVQAEAGGMHTVCLSK 84
Query: 489 WGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 668
GQ +S+G + G LG + + L K V+QV+ G H+ ALT+ G ++ W
Sbjct: 85 SGQVYSFGCNDEGALGRDTSVEGSEMVPGKVELQEK-VVQVSAGDSHTAALTDDGRVFLW 143
Query: 669 GA--NSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFVLSKSGAVFGWGKNTH 842
G+ ++ G GL K M P + + VP+ +A GN+H +L+ G ++ G
Sbjct: 144 GSFRDNNGVIGLLEPMKKSMVPVQVQ--LDVPVVKVASGNDHLVMLTADGDLYTLGCGEQ 201
Query: 843 GXLG 854
G LG
Sbjct: 202 GQLG 205
Score = 76.6 bits (180), Expect = 1e-13
Identities = 60/205 (29%), Positives = 94/205 (45%), Gaps = 17/205 (8%)
Frame = +3
Query: 291 VAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTE--SDNGKNPALVETF-KDCTI------ 443
VA+G H + L+ G LY+ G + GQLGR E ++ G L C +
Sbjct: 177 VASGNDHLVMLTADGDLYTLGCGEQGQLGRVPELFANRGGRQGLERLLVPKCVMLKSRGS 236
Query: 444 ------STIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGL--ATKN 599
CG + AI G + +G + QLG G + P+ + +TK+
Sbjct: 237 RGHVRFQDAFCGAYFTFAISHEGHVYGFGLSNYHQLGTP-GTESCFIPQNLTSFKNSTKS 295
Query: 600 VIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACG 779
+ + G +H+V + + G YS G YG+ GLG + ++ P IS L V + +ACG
Sbjct: 296 WVGFSGGQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPAV--SSVACG 353
Query: 780 NNHTFVLSKSGAVFGWGKNTHGXLG 854
+ + ++K G VF WG T+ LG
Sbjct: 354 ASVGYAVTKDGRVFAWGMGTNYQLG 378
Score = 75.4 bits (177), Expect = 3e-13
Identities = 71/222 (31%), Positives = 103/222 (46%), Gaps = 19/222 (8%)
Frame = +3
Query: 246 KPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKN-PALVE 422
KP L E D +QA A G H++ LS SG +YS G ND G LGR T + + P VE
Sbjct: 59 KPALVSIPE-DVVQAEAGG-MHTVCLSKSGQVYSFGCNDEGALGRDTSVEGSEMVPGKVE 116
Query: 423 TFKDCTISTIACGLQHSLAIDEWGQPFSWGS--DSMGQLGNNLGAHAQDKPKFVKGLATK 596
+ + ++ G H+ A+ + G+ F WGS D+ G +G L + V+
Sbjct: 117 LQE--KVVQVSAGDSHTAALTDDGRVFLWGSFRDNNGVIG--LLEPMKKSMVPVQVQLDV 172
Query: 597 NVIQVACGAYHSVALTNSGDLYSWGANSYGQCG-LGTISNKEMSPQHISSLIGVPIALIA 773
V++VA G H V LT GDLY+ G GQ G + + Q + L+ VP ++
Sbjct: 173 PVVKVASGNDHLVMLTADGDLYTLGCGEQGQLGRVPELFANRGGRQGLERLL-VPKCVML 231
Query: 774 ---------------CGNNHTFVLSKSGAVFGWGKNTHGXLG 854
CG TF +S G V+G+G + + LG
Sbjct: 232 KSRGSRGHVRFQDAFCGAYFTFAISHEGHVYGFGLSNYHQLG 273
Score = 68.9 bits (161), Expect = 2e-11
Identities = 48/177 (27%), Positives = 83/177 (46%), Gaps = 3/177 (1%)
Frame = +3
Query: 285 QAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIAC-- 458
Q G + + +S+ GH+Y G ++ QLG +++ P + +FK+ T S +
Sbjct: 243 QDAFCGAYFTFAISHEGHVYGFGLSNYHQLGTPG-TESCFIPQNLTSFKNSTKSWVGFSG 301
Query: 459 GLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVA 638
G H++ +D G+ +S G G+LG GA + P + L V VACGA A
Sbjct: 302 GQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPA--VSSVACGASVGYA 359
Query: 639 LTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIAL-IACGNNHTFVLSK 806
+T G +++WG + Q G G + + + + + L ++ G HT +L K
Sbjct: 360 VTKDGRVFAWGMGTNYQLGTGQDEDAWSPVEMMGKQLENRVVLSVSSGGQHTVLLVK 416
>CR407693-1|CAG28621.1| 421|Homo sapiens CHC1 protein.
Length = 421
Score = 85.0 bits (201), Expect = 3e-16
Identities = 55/184 (29%), Positives = 88/184 (47%), Gaps = 2/184 (1%)
Frame = +3
Query: 309 HSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDE 488
H + + G + + G DVGQLG K PALV +D + G H++ + +
Sbjct: 27 HRSHSTEPGLVLTLGQGDVGQLGLGENVMERKKPALVSIPED--VVQAEAGGMHTVCLSK 84
Query: 489 WGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 668
GQ +S+G + G LG + + L K V+QV+ G H+ ALT+ G ++ W
Sbjct: 85 SGQVYSFGCNDEGALGRDTSVEGSEMVPGKVELQEK-VVQVSAGDSHTAALTDDGRVFLW 143
Query: 669 GA--NSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFVLSKSGAVFGWGKNTH 842
G+ ++ G GL K M P + + VP+ +A GN+H +L+ G ++ G
Sbjct: 144 GSFRDNNGVIGLLEPMKKSMVPVQVQ--LDVPVVKVASGNDHLVMLTADGDLYTLGCGEQ 201
Query: 843 GXLG 854
G LG
Sbjct: 202 GQLG 205
Score = 76.6 bits (180), Expect = 1e-13
Identities = 60/205 (29%), Positives = 94/205 (45%), Gaps = 17/205 (8%)
Frame = +3
Query: 291 VAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTE--SDNGKNPALVETF-KDCTI------ 443
VA+G H + L+ G LY+ G + GQLGR E ++ G L C +
Sbjct: 177 VASGNDHLVMLTADGDLYTLGCGEQGQLGRVPELFANRGGRQGLERLLVPKCVMLKSRGS 236
Query: 444 ------STIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGL--ATKN 599
CG + AI G + +G + QLG G + P+ + +TK+
Sbjct: 237 RGHVRFQDAFCGAYFTFAISHEGHVYGFGLSNYHQLGTP-GTESCFIPQNLTSFKNSTKS 295
Query: 600 VIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACG 779
+ + G +H+V + + G YS G YG+ GLG + ++ P IS L V + +ACG
Sbjct: 296 WVGFSGGQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPAV--SSVACG 353
Query: 780 NNHTFVLSKSGAVFGWGKNTHGXLG 854
+ + ++K G VF WG T+ LG
Sbjct: 354 ASVGYAVTKDGRVFAWGMGTNYQLG 378
Score = 75.4 bits (177), Expect = 3e-13
Identities = 71/222 (31%), Positives = 103/222 (46%), Gaps = 19/222 (8%)
Frame = +3
Query: 246 KPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKN-PALVE 422
KP L E D +QA A G H++ LS SG +YS G ND G LGR T + + P VE
Sbjct: 59 KPALVSIPE-DVVQAEAGG-MHTVCLSKSGQVYSFGCNDEGALGRDTSVEGSEMVPGKVE 116
Query: 423 TFKDCTISTIACGLQHSLAIDEWGQPFSWGS--DSMGQLGNNLGAHAQDKPKFVKGLATK 596
+ + ++ G H+ A+ + G+ F WGS D+ G +G L + V+
Sbjct: 117 LQE--KVVQVSAGDSHTAALTDDGRVFLWGSFRDNNGVIG--LLEPMKKSMVPVQVQLDV 172
Query: 597 NVIQVACGAYHSVALTNSGDLYSWGANSYGQCG-LGTISNKEMSPQHISSLIGVPIALIA 773
V++VA G H V LT GDLY+ G GQ G + + Q + L+ VP ++
Sbjct: 173 PVVKVASGNDHLVMLTADGDLYTLGCGEQGQLGRVPELFANRGGRQGLERLL-VPKCVML 231
Query: 774 ---------------CGNNHTFVLSKSGAVFGWGKNTHGXLG 854
CG TF +S G V+G+G + + LG
Sbjct: 232 KSRGSRGHVRFQDAFCGAYFTFAISHEGHVYGFGLSNYHQLG 273
Score = 68.9 bits (161), Expect = 2e-11
Identities = 48/177 (27%), Positives = 83/177 (46%), Gaps = 3/177 (1%)
Frame = +3
Query: 285 QAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIAC-- 458
Q G + + +S+ GH+Y G ++ QLG +++ P + +FK+ T S +
Sbjct: 243 QDAFCGAYFTFAISHEGHVYGFGLSNYHQLGTPG-TESCFIPQNLTSFKNSTKSWVGFSG 301
Query: 459 GLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVA 638
G H++ +D G+ +S G G+LG GA + P + L V VACGA A
Sbjct: 302 GQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPA--VSSVACGASVGYA 359
Query: 639 LTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIAL-IACGNNHTFVLSK 806
+T G +++WG + Q G G + + + + + L ++ G HT +L K
Sbjct: 360 VTKDGRVFAWGMGTNYQLGTGQDEDAWSPVEMMGKQLENRVVLSVSSGGQHTVLLVK 416
>BC069198-1|AAH69198.1| 452|Homo sapiens regulator of chromosome
condensation 1 protein.
Length = 452
Score = 85.0 bits (201), Expect = 3e-16
Identities = 55/184 (29%), Positives = 88/184 (47%), Gaps = 2/184 (1%)
Frame = +3
Query: 309 HSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDE 488
H + + G + + G DVGQLG K PALV +D + G H++ + +
Sbjct: 58 HRSHSTEPGLVLTLGQGDVGQLGLGENVMERKKPALVSIPED--VVQAEAGGMHTVCLSK 115
Query: 489 WGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 668
GQ +S+G + G LG + + L K V+QV+ G H+ ALT+ G ++ W
Sbjct: 116 SGQVYSFGCNDEGALGRDTSVEGSEMVPGKVELQEK-VVQVSAGDSHTAALTDDGRVFLW 174
Query: 669 GA--NSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFVLSKSGAVFGWGKNTH 842
G+ ++ G GL K M P + + VP+ +A GN+H +L+ G ++ G
Sbjct: 175 GSFRDNNGVIGLLEPMKKSMVPVQVQ--LDVPVVKVASGNDHLVMLTADGDLYTLGCGEQ 232
Query: 843 GXLG 854
G LG
Sbjct: 233 GQLG 236
Score = 76.6 bits (180), Expect = 1e-13
Identities = 60/205 (29%), Positives = 94/205 (45%), Gaps = 17/205 (8%)
Frame = +3
Query: 291 VAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTE--SDNGKNPALVETF-KDCTI------ 443
VA+G H + L+ G LY+ G + GQLGR E ++ G L C +
Sbjct: 208 VASGNDHLVMLTADGDLYTLGCGEQGQLGRVPELFANRGGRQGLERLLVPKCVMLKSRGS 267
Query: 444 ------STIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGL--ATKN 599
CG + AI G + +G + QLG G + P+ + +TK+
Sbjct: 268 RGHVRFQDAFCGAYFTFAISHEGHVYGFGLSNYHQLGTP-GTESCFIPQNLTSFKNSTKS 326
Query: 600 VIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACG 779
+ + G +H+V + + G YS G YG+ GLG + ++ P IS L V + +ACG
Sbjct: 327 WVGFSGGQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPAV--SSVACG 384
Query: 780 NNHTFVLSKSGAVFGWGKNTHGXLG 854
+ + ++K G VF WG T+ LG
Sbjct: 385 ASVGYAVTKDGRVFAWGMGTNYQLG 409
Score = 75.4 bits (177), Expect = 3e-13
Identities = 71/222 (31%), Positives = 103/222 (46%), Gaps = 19/222 (8%)
Frame = +3
Query: 246 KPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKN-PALVE 422
KP L E D +QA A G H++ LS SG +YS G ND G LGR T + + P VE
Sbjct: 90 KPALVSIPE-DVVQAEAGG-MHTVCLSKSGQVYSFGCNDEGALGRDTSVEGSEMVPGKVE 147
Query: 423 TFKDCTISTIACGLQHSLAIDEWGQPFSWGS--DSMGQLGNNLGAHAQDKPKFVKGLATK 596
+ + ++ G H+ A+ + G+ F WGS D+ G +G L + V+
Sbjct: 148 LQE--KVVQVSAGDSHTAALTDDGRVFLWGSFRDNNGVIG--LLEPMKKSMVPVQVQLDV 203
Query: 597 NVIQVACGAYHSVALTNSGDLYSWGANSYGQCG-LGTISNKEMSPQHISSLIGVPIALIA 773
V++VA G H V LT GDLY+ G GQ G + + Q + L+ VP ++
Sbjct: 204 PVVKVASGNDHLVMLTADGDLYTLGCGEQGQLGRVPELFANRGGRQGLERLL-VPKCVML 262
Query: 774 ---------------CGNNHTFVLSKSGAVFGWGKNTHGXLG 854
CG TF +S G V+G+G + + LG
Sbjct: 263 KSRGSRGHVRFQDAFCGAYFTFAISHEGHVYGFGLSNYHQLG 304
Score = 68.9 bits (161), Expect = 2e-11
Identities = 48/177 (27%), Positives = 83/177 (46%), Gaps = 3/177 (1%)
Frame = +3
Query: 285 QAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIAC-- 458
Q G + + +S+ GH+Y G ++ QLG +++ P + +FK+ T S +
Sbjct: 274 QDAFCGAYFTFAISHEGHVYGFGLSNYHQLGTPG-TESCFIPQNLTSFKNSTKSWVGFSG 332
Query: 459 GLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVA 638
G H++ +D G+ +S G G+LG GA + P + L V VACGA A
Sbjct: 333 GQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPA--VSSVACGASVGYA 390
Query: 639 LTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIAL-IACGNNHTFVLSK 806
+T G +++WG + Q G G + + + + + L ++ G HT +L K
Sbjct: 391 VTKDGRVFAWGMGTNYQLGTGQDEDAWSPVEMMGKQLENRVVLSVSSGGQHTVLLVK 447
>BC036903-1|AAH36903.1| 421|Homo sapiens regulator of chromosome
condensation 1 protein.
Length = 421
Score = 85.0 bits (201), Expect = 3e-16
Identities = 55/184 (29%), Positives = 88/184 (47%), Gaps = 2/184 (1%)
Frame = +3
Query: 309 HSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDE 488
H + + G + + G DVGQLG K PALV +D + G H++ + +
Sbjct: 27 HRSHSTEPGLVLTLGQGDVGQLGLGENVMERKKPALVSIPED--VVQAEAGGMHTVCLSK 84
Query: 489 WGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 668
GQ +S+G + G LG + + L K V+QV+ G H+ ALT+ G ++ W
Sbjct: 85 SGQVYSFGCNDEGALGRDTSVEGSEMVPGKVELQEK-VVQVSAGDSHTAALTDDGRVFLW 143
Query: 669 GA--NSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFVLSKSGAVFGWGKNTH 842
G+ ++ G GL K M P + + VP+ +A GN+H +L+ G ++ G
Sbjct: 144 GSFRDNNGVIGLLEPMKKSMVPVQVQ--LDVPVVKVASGNDHLVMLTADGDLYTLGCGEQ 201
Query: 843 GXLG 854
G LG
Sbjct: 202 GQLG 205
Score = 76.6 bits (180), Expect = 1e-13
Identities = 60/205 (29%), Positives = 94/205 (45%), Gaps = 17/205 (8%)
Frame = +3
Query: 291 VAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTE--SDNGKNPALVETF-KDCTI------ 443
VA+G H + L+ G LY+ G + GQLGR E ++ G L C +
Sbjct: 177 VASGNDHLVMLTADGDLYTLGCGEQGQLGRVPELFANRGGRQGLERLLVPKCVMLKSRGS 236
Query: 444 ------STIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGL--ATKN 599
CG + AI G + +G + QLG G + P+ + +TK+
Sbjct: 237 RGHVRFQDAFCGAYFTFAISHEGHVYGFGLSNYHQLGTP-GTESCFIPQNLTSFKNSTKS 295
Query: 600 VIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACG 779
+ + G +H+V + + G YS G YG+ GLG + ++ P IS L V + +ACG
Sbjct: 296 WVGFSGGQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPAV--SSVACG 353
Query: 780 NNHTFVLSKSGAVFGWGKNTHGXLG 854
+ + ++K G VF WG T+ LG
Sbjct: 354 ASVGYAVTKDGRVFAWGMGTNYQLG 378
Score = 75.4 bits (177), Expect = 3e-13
Identities = 71/222 (31%), Positives = 103/222 (46%), Gaps = 19/222 (8%)
Frame = +3
Query: 246 KPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKN-PALVE 422
KP L E D +QA A G H++ LS SG +YS G ND G LGR T + + P VE
Sbjct: 59 KPALVSIPE-DVVQAEAGG-MHTVCLSKSGQVYSFGCNDEGALGRDTSVEGSEMVPGKVE 116
Query: 423 TFKDCTISTIACGLQHSLAIDEWGQPFSWGS--DSMGQLGNNLGAHAQDKPKFVKGLATK 596
+ + ++ G H+ A+ + G+ F WGS D+ G +G L + V+
Sbjct: 117 LQE--KVVQVSAGDSHTAALTDDGRVFLWGSFRDNNGVIG--LLEPMKKSMVPVQVQLDV 172
Query: 597 NVIQVACGAYHSVALTNSGDLYSWGANSYGQCG-LGTISNKEMSPQHISSLIGVPIALIA 773
V++VA G H V LT GDLY+ G GQ G + + Q + L+ VP ++
Sbjct: 173 PVVKVASGNDHLVMLTADGDLYTLGCGEQGQLGRVPELFANRGGRQGLERLL-VPKCVML 231
Query: 774 ---------------CGNNHTFVLSKSGAVFGWGKNTHGXLG 854
CG TF +S G V+G+G + + LG
Sbjct: 232 KSRGSRGHVRFQDAFCGAYFTFAISHEGHVYGFGLSNYHQLG 273
Score = 68.9 bits (161), Expect = 2e-11
Identities = 48/177 (27%), Positives = 83/177 (46%), Gaps = 3/177 (1%)
Frame = +3
Query: 285 QAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIAC-- 458
Q G + + +S+ GH+Y G ++ QLG +++ P + +FK+ T S +
Sbjct: 243 QDAFCGAYFTFAISHEGHVYGFGLSNYHQLGTPG-TESCFIPQNLTSFKNSTKSWVGFSG 301
Query: 459 GLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVA 638
G H++ +D G+ +S G G+LG GA + P + L V VACGA A
Sbjct: 302 GQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPA--VSSVACGASVGYA 359
Query: 639 LTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIAL-IACGNNHTFVLSK 806
+T G +++WG + Q G G + + + + + L ++ G HT +L K
Sbjct: 360 VTKDGRVFAWGMGTNYQLGTGQDEDAWSPVEMMGKQLENRVVLSVSSGGQHTVLLVK 416
>BC010067-1|AAH10067.1| 421|Homo sapiens regulator of chromosome
condensation 1 protein.
Length = 421
Score = 85.0 bits (201), Expect = 3e-16
Identities = 55/184 (29%), Positives = 88/184 (47%), Gaps = 2/184 (1%)
Frame = +3
Query: 309 HSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDE 488
H + + G + + G DVGQLG K PALV +D + G H++ + +
Sbjct: 27 HRSHSTEPGLVLTLGQGDVGQLGLGENVMERKKPALVSIPED--VVQAEAGGMHTVCLSK 84
Query: 489 WGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 668
GQ +S+G + G LG + + L K V+QV+ G H+ ALT+ G ++ W
Sbjct: 85 SGQVYSFGCNDEGALGRDTSVEGSEMVPGKVELQEK-VVQVSAGDSHTAALTDDGRVFLW 143
Query: 669 GA--NSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFVLSKSGAVFGWGKNTH 842
G+ ++ G GL K M P + + VP+ +A GN+H +L+ G ++ G
Sbjct: 144 GSFRDNNGVIGLLEPMKKSMVPVQVQ--LDVPVVKVASGNDHLVMLTADGDLYTLGCGEQ 201
Query: 843 GXLG 854
G LG
Sbjct: 202 GQLG 205
Score = 76.6 bits (180), Expect = 1e-13
Identities = 60/205 (29%), Positives = 94/205 (45%), Gaps = 17/205 (8%)
Frame = +3
Query: 291 VAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTE--SDNGKNPALVETF-KDCTI------ 443
VA+G H + L+ G LY+ G + GQLGR E ++ G L C +
Sbjct: 177 VASGNDHLVMLTADGDLYTLGCGEQGQLGRVPELFANRGGRQGLERLLVPKCVMLKSRGS 236
Query: 444 ------STIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGL--ATKN 599
CG + AI G + +G + QLG G + P+ + +TK+
Sbjct: 237 RGHVRFQDAFCGAYFTFAISHEGHVYGFGLSNYHQLGTP-GTESCFIPQNLTSFKNSTKS 295
Query: 600 VIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACG 779
+ + G +H+V + + G YS G YG+ GLG + ++ P IS L V + +ACG
Sbjct: 296 WVGFSGGQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPAV--SSVACG 353
Query: 780 NNHTFVLSKSGAVFGWGKNTHGXLG 854
+ + ++K G VF WG T+ LG
Sbjct: 354 ASVGYAVTKDGRVFAWGMGTNYQLG 378
Score = 75.4 bits (177), Expect = 3e-13
Identities = 71/222 (31%), Positives = 103/222 (46%), Gaps = 19/222 (8%)
Frame = +3
Query: 246 KPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKN-PALVE 422
KP L E D +QA A G H++ LS SG +YS G ND G LGR T + + P VE
Sbjct: 59 KPALVSIPE-DVVQAEAGG-MHTVCLSKSGQVYSFGCNDEGALGRDTSVEGSEMVPGKVE 116
Query: 423 TFKDCTISTIACGLQHSLAIDEWGQPFSWGS--DSMGQLGNNLGAHAQDKPKFVKGLATK 596
+ + ++ G H+ A+ + G+ F WGS D+ G +G L + V+
Sbjct: 117 LQE--KVVQVSAGDSHTAALTDDGRVFLWGSFRDNNGVIG--LLEPMKKSMVPVQVQLDV 172
Query: 597 NVIQVACGAYHSVALTNSGDLYSWGANSYGQCG-LGTISNKEMSPQHISSLIGVPIALIA 773
V++VA G H V LT GDLY+ G GQ G + + Q + L+ VP ++
Sbjct: 173 PVVKVASGNDHLVMLTADGDLYTLGCGEQGQLGRVPELFANRGGRQGLERLL-VPKCVML 231
Query: 774 ---------------CGNNHTFVLSKSGAVFGWGKNTHGXLG 854
CG TF +S G V+G+G + + LG
Sbjct: 232 KSRGSRGHVRFQDAFCGAYFTFAISHEGHVYGFGLSNYHQLG 273
Score = 68.9 bits (161), Expect = 2e-11
Identities = 48/177 (27%), Positives = 83/177 (46%), Gaps = 3/177 (1%)
Frame = +3
Query: 285 QAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIAC-- 458
Q G + + +S+ GH+Y G ++ QLG +++ P + +FK+ T S +
Sbjct: 243 QDAFCGAYFTFAISHEGHVYGFGLSNYHQLGTPG-TESCFIPQNLTSFKNSTKSWVGFSG 301
Query: 459 GLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVA 638
G H++ +D G+ +S G G+LG GA + P + L V VACGA A
Sbjct: 302 GQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPA--VSSVACGASVGYA 359
Query: 639 LTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIAL-IACGNNHTFVLSK 806
+T G +++WG + Q G G + + + + + L ++ G HT +L K
Sbjct: 360 VTKDGRVFAWGMGTNYQLGTGQDEDAWSPVEMMGKQLENRVVLSVSSGGQHTVLLVK 416
>BC007300-1|AAH07300.1| 421|Homo sapiens regulator of chromosome
condensation 1 protein.
Length = 421
Score = 85.0 bits (201), Expect = 3e-16
Identities = 55/184 (29%), Positives = 88/184 (47%), Gaps = 2/184 (1%)
Frame = +3
Query: 309 HSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDE 488
H + + G + + G DVGQLG K PALV +D + G H++ + +
Sbjct: 27 HRSHSTEPGLVLTLGQGDVGQLGLGENVMERKKPALVSIPED--VVQAEAGGMHTVCLSK 84
Query: 489 WGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 668
GQ +S+G + G LG + + L K V+QV+ G H+ ALT+ G ++ W
Sbjct: 85 SGQVYSFGCNDEGALGRDTSVEGSEMVPGKVELQEK-VVQVSAGDSHTAALTDDGRVFLW 143
Query: 669 GA--NSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFVLSKSGAVFGWGKNTH 842
G+ ++ G GL K M P + + VP+ +A GN+H +L+ G ++ G
Sbjct: 144 GSFRDNNGVIGLLEPMKKSMVPVQVQ--LDVPVVKVASGNDHLVMLTADGDLYTLGCGEQ 201
Query: 843 GXLG 854
G LG
Sbjct: 202 GQLG 205
Score = 76.6 bits (180), Expect = 1e-13
Identities = 60/205 (29%), Positives = 94/205 (45%), Gaps = 17/205 (8%)
Frame = +3
Query: 291 VAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTE--SDNGKNPALVETF-KDCTI------ 443
VA+G H + L+ G LY+ G + GQLGR E ++ G L C +
Sbjct: 177 VASGNDHLVMLTADGDLYTLGCGEQGQLGRVPELFANRGGRQGLERLLVPKCVMLKSRGS 236
Query: 444 ------STIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGL--ATKN 599
CG + AI G + +G + QLG G + P+ + +TK+
Sbjct: 237 RGHVRFQDAFCGAYFTFAISHEGHVYGFGLSNYHQLGTP-GTESCFIPQNLTSFKNSTKS 295
Query: 600 VIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACG 779
+ + G +H+V + + G YS G YG+ GLG + ++ P IS L V + +ACG
Sbjct: 296 WVGFSGGQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPAV--SSVACG 353
Query: 780 NNHTFVLSKSGAVFGWGKNTHGXLG 854
+ + ++K G VF WG T+ LG
Sbjct: 354 ASVGYAVTKDGRVFAWGMGTNYQLG 378
Score = 75.4 bits (177), Expect = 3e-13
Identities = 71/222 (31%), Positives = 103/222 (46%), Gaps = 19/222 (8%)
Frame = +3
Query: 246 KPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKN-PALVE 422
KP L E D +QA A G H++ LS SG +YS G ND G LGR T + + P VE
Sbjct: 59 KPALVSIPE-DVVQAEAGG-MHTVCLSKSGQVYSFGCNDEGALGRDTSVEGSEMVPGKVE 116
Query: 423 TFKDCTISTIACGLQHSLAIDEWGQPFSWGS--DSMGQLGNNLGAHAQDKPKFVKGLATK 596
+ + ++ G H+ A+ + G+ F WGS D+ G +G L + V+
Sbjct: 117 LQE--KVVQVSAGDSHTAALTDDGRVFLWGSFRDNNGVIG--LLEPMKKSMVPVQVQLDV 172
Query: 597 NVIQVACGAYHSVALTNSGDLYSWGANSYGQCG-LGTISNKEMSPQHISSLIGVPIALIA 773
V++VA G H V LT GDLY+ G GQ G + + Q + L+ VP ++
Sbjct: 173 PVVKVASGNDHLVMLTADGDLYTLGCGEQGQLGRVPELFANRGGRQGLERLL-VPKCVML 231
Query: 774 ---------------CGNNHTFVLSKSGAVFGWGKNTHGXLG 854
CG TF +S G V+G+G + + LG
Sbjct: 232 KSRGSRGHVRFQDAFCGAYFTFAISHEGHVYGFGLSNYHQLG 273
Score = 68.9 bits (161), Expect = 2e-11
Identities = 48/177 (27%), Positives = 83/177 (46%), Gaps = 3/177 (1%)
Frame = +3
Query: 285 QAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIAC-- 458
Q G + + +S+ GH+Y G ++ QLG +++ P + +FK+ T S +
Sbjct: 243 QDAFCGAYFTFAISHEGHVYGFGLSNYHQLGTPG-TESCFIPQNLTSFKNSTKSWVGFSG 301
Query: 459 GLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVA 638
G H++ +D G+ +S G G+LG GA + P + L V VACGA A
Sbjct: 302 GQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPA--VSSVACGASVGYA 359
Query: 639 LTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIAL-IACGNNHTFVLSK 806
+T G +++WG + Q G G + + + + + L ++ G HT +L K
Sbjct: 360 VTKDGRVFAWGMGTNYQLGTGQDEDAWSPVEMMGKQLENRVVLSVSSGGQHTVLLVK 416
>AL513497-2|CAI22287.1| 421|Homo sapiens regulator of chromosome
condensation 1 protein.
Length = 421
Score = 85.0 bits (201), Expect = 3e-16
Identities = 55/184 (29%), Positives = 88/184 (47%), Gaps = 2/184 (1%)
Frame = +3
Query: 309 HSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDE 488
H + + G + + G DVGQLG K PALV +D + G H++ + +
Sbjct: 27 HRSHSTEPGLVLTLGQGDVGQLGLGENVMERKKPALVSIPED--VVQAEAGGMHTVCLSK 84
Query: 489 WGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 668
GQ +S+G + G LG + + L K V+QV+ G H+ ALT+ G ++ W
Sbjct: 85 SGQVYSFGCNDEGALGRDTSVEGSEMVPGKVELQEK-VVQVSAGDSHTAALTDDGRVFLW 143
Query: 669 GA--NSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFVLSKSGAVFGWGKNTH 842
G+ ++ G GL K M P + + VP+ +A GN+H +L+ G ++ G
Sbjct: 144 GSFRDNNGVIGLLEPMKKSMVPVQVQ--LDVPVVKVASGNDHLVMLTADGDLYTLGCGEQ 201
Query: 843 GXLG 854
G LG
Sbjct: 202 GQLG 205
Score = 76.6 bits (180), Expect = 1e-13
Identities = 60/205 (29%), Positives = 94/205 (45%), Gaps = 17/205 (8%)
Frame = +3
Query: 291 VAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTE--SDNGKNPALVETF-KDCTI------ 443
VA+G H + L+ G LY+ G + GQLGR E ++ G L C +
Sbjct: 177 VASGNDHLVMLTADGDLYTLGCGEQGQLGRVPELFANRGGRQGLERLLVPKCVMLKSRGS 236
Query: 444 ------STIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGL--ATKN 599
CG + AI G + +G + QLG G + P+ + +TK+
Sbjct: 237 RGHVRFQDAFCGAYFTFAISHEGHVYGFGLSNYHQLGTP-GTESCFIPQNLTSFKNSTKS 295
Query: 600 VIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACG 779
+ + G +H+V + + G YS G YG+ GLG + ++ P IS L V + +ACG
Sbjct: 296 WVGFSGGQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPAV--SSVACG 353
Query: 780 NNHTFVLSKSGAVFGWGKNTHGXLG 854
+ + ++K G VF WG T+ LG
Sbjct: 354 ASVGYAVTKDGRVFAWGMGTNYQLG 378
Score = 75.4 bits (177), Expect = 3e-13
Identities = 71/222 (31%), Positives = 103/222 (46%), Gaps = 19/222 (8%)
Frame = +3
Query: 246 KPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKN-PALVE 422
KP L E D +QA A G H++ LS SG +YS G ND G LGR T + + P VE
Sbjct: 59 KPALVSIPE-DVVQAEAGG-MHTVCLSKSGQVYSFGCNDEGALGRDTSVEGSEMVPGKVE 116
Query: 423 TFKDCTISTIACGLQHSLAIDEWGQPFSWGS--DSMGQLGNNLGAHAQDKPKFVKGLATK 596
+ + ++ G H+ A+ + G+ F WGS D+ G +G L + V+
Sbjct: 117 LQE--KVVQVSAGDSHTAALTDDGRVFLWGSFRDNNGVIG--LLEPMKKSMVPVQVQLDV 172
Query: 597 NVIQVACGAYHSVALTNSGDLYSWGANSYGQCG-LGTISNKEMSPQHISSLIGVPIALIA 773
V++VA G H V LT GDLY+ G GQ G + + Q + L+ VP ++
Sbjct: 173 PVVKVASGNDHLVMLTADGDLYTLGCGEQGQLGRVPELFANRGGRQGLERLL-VPKCVML 231
Query: 774 ---------------CGNNHTFVLSKSGAVFGWGKNTHGXLG 854
CG TF +S G V+G+G + + LG
Sbjct: 232 KSRGSRGHVRFQDAFCGAYFTFAISHEGHVYGFGLSNYHQLG 273
Score = 68.9 bits (161), Expect = 2e-11
Identities = 48/177 (27%), Positives = 83/177 (46%), Gaps = 3/177 (1%)
Frame = +3
Query: 285 QAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIAC-- 458
Q G + + +S+ GH+Y G ++ QLG +++ P + +FK+ T S +
Sbjct: 243 QDAFCGAYFTFAISHEGHVYGFGLSNYHQLGTPG-TESCFIPQNLTSFKNSTKSWVGFSG 301
Query: 459 GLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVA 638
G H++ +D G+ +S G G+LG GA + P + L V VACGA A
Sbjct: 302 GQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPA--VSSVACGASVGYA 359
Query: 639 LTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIAL-IACGNNHTFVLSK 806
+T G +++WG + Q G G + + + + + L ++ G HT +L K
Sbjct: 360 VTKDGRVFAWGMGTNYQLGTGQDEDAWSPVEMMGKQLENRVVLSVSSGGQHTVLLVK 416
>AF498924-1|AAM21072.1| 421|Homo sapiens regulator of chromosome
condensation 1 protein.
Length = 421
Score = 85.0 bits (201), Expect = 3e-16
Identities = 55/184 (29%), Positives = 88/184 (47%), Gaps = 2/184 (1%)
Frame = +3
Query: 309 HSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDE 488
H + + G + + G DVGQLG K PALV +D + G H++ + +
Sbjct: 27 HRSHSTEPGLVLTLGQGDVGQLGLGENVMERKKPALVSIPED--VVQAEAGGMHTVCLSK 84
Query: 489 WGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 668
GQ +S+G + G LG + + L K V+QV+ G H+ ALT+ G ++ W
Sbjct: 85 SGQVYSFGCNDEGALGRDTSVEGSEMVPGKVELQEK-VVQVSAGDSHTAALTDDGRVFLW 143
Query: 669 GA--NSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFVLSKSGAVFGWGKNTH 842
G+ ++ G GL K M P + + VP+ +A GN+H +L+ G ++ G
Sbjct: 144 GSFRDNNGVIGLLEPMKKSMVPVQVQ--LDVPVVKVASGNDHLVMLTADGDLYTLGCGEQ 201
Query: 843 GXLG 854
G LG
Sbjct: 202 GQLG 205
Score = 76.6 bits (180), Expect = 1e-13
Identities = 60/205 (29%), Positives = 94/205 (45%), Gaps = 17/205 (8%)
Frame = +3
Query: 291 VAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTE--SDNGKNPALVETF-KDCTI------ 443
VA+G H + L+ G LY+ G + GQLGR E ++ G L C +
Sbjct: 177 VASGNDHLVMLTADGDLYTLGCGEQGQLGRVPELFANRGGRQGLERLLVPKCVMLKSRGS 236
Query: 444 ------STIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGL--ATKN 599
CG + AI G + +G + QLG G + P+ + +TK+
Sbjct: 237 RGHVRFQDAFCGAYFTFAISHEGHVYGFGLSNYHQLGTP-GTESCFIPQNLTSFKNSTKS 295
Query: 600 VIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACG 779
+ + G +H+V + + G YS G YG+ GLG + ++ P IS L V + +ACG
Sbjct: 296 WVGFSGGQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPAV--SSVACG 353
Query: 780 NNHTFVLSKSGAVFGWGKNTHGXLG 854
+ + ++K G VF WG T+ LG
Sbjct: 354 ASVGYAVTKDGRVFAWGMGTNYQLG 378
Score = 75.4 bits (177), Expect = 3e-13
Identities = 71/222 (31%), Positives = 103/222 (46%), Gaps = 19/222 (8%)
Frame = +3
Query: 246 KPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKN-PALVE 422
KP L E D +QA A G H++ LS SG +YS G ND G LGR T + + P VE
Sbjct: 59 KPALVSIPE-DVVQAEAGG-MHTVCLSKSGQVYSFGCNDEGALGRDTSVEGSEMVPGKVE 116
Query: 423 TFKDCTISTIACGLQHSLAIDEWGQPFSWGS--DSMGQLGNNLGAHAQDKPKFVKGLATK 596
+ + ++ G H+ A+ + G+ F WGS D+ G +G L + V+
Sbjct: 117 LQE--KVVQVSAGDSHTAALTDDGRVFLWGSFRDNNGVIG--LLEPMKKSMVPVQVQLDV 172
Query: 597 NVIQVACGAYHSVALTNSGDLYSWGANSYGQCG-LGTISNKEMSPQHISSLIGVPIALIA 773
V++VA G H V LT GDLY+ G GQ G + + Q + L+ VP ++
Sbjct: 173 PVVKVASGNDHLVMLTADGDLYTLGCGEQGQLGRVPELFANRGGRQGLERLL-VPKCVML 231
Query: 774 ---------------CGNNHTFVLSKSGAVFGWGKNTHGXLG 854
CG TF +S G V+G+G + + LG
Sbjct: 232 KSRGSRGHVRFQDAFCGAYFTFAISHEGHVYGFGLSNYHQLG 273
Score = 68.9 bits (161), Expect = 2e-11
Identities = 48/177 (27%), Positives = 83/177 (46%), Gaps = 3/177 (1%)
Frame = +3
Query: 285 QAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIAC-- 458
Q G + + +S+ GH+Y G ++ QLG +++ P + +FK+ T S +
Sbjct: 243 QDAFCGAYFTFAISHEGHVYGFGLSNYHQLGTPG-TESCFIPQNLTSFKNSTKSWVGFSG 301
Query: 459 GLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVA 638
G H++ +D G+ +S G G+LG GA + P + L V VACGA A
Sbjct: 302 GQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPA--VSSVACGASVGYA 359
Query: 639 LTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIAL-IACGNNHTFVLSK 806
+T G +++WG + Q G G + + + + + L ++ G HT +L K
Sbjct: 360 VTKDGRVFAWGMGTNYQLGTGQDEDAWSPVEMMGKQLENRVVLSVSSGGQHTVLLVK 416
>BC032712-1|AAH32712.1| 454|Homo sapiens WBSCR16 protein protein.
Length = 454
Score = 82.6 bits (195), Expect = 2e-15
Identities = 64/200 (32%), Positives = 93/200 (46%), Gaps = 5/200 (2%)
Frame = +3
Query: 270 ESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQ-TESDNGKNPALVETFKDC--T 440
+ + V+ G HSL L++ ++S GNN GQ GR+ E++ V +D
Sbjct: 172 QETRVLQVSCGRAHSLVLTDREGVFSMGNNSYGQCGRKVVENEIYSESHRVHRMQDFDGQ 231
Query: 441 ISTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACG 620
+ +ACG HSL + + G+ +S G + GQ G K LA NVIQVA
Sbjct: 232 VVQVACGQDHSLFLTDKGEVYSCGWGADGQTGLGHYNITSSPTKLGGDLAGVNVIQVATY 291
Query: 621 AYHSVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQ--HISSLIGVPIALIACGNNHTF 794
+A++ G L+ WG + Y Q T S + P+ H S +G + ACG
Sbjct: 292 GDCCLAVSADGGLFGWGNSEYLQLASVTDSTQVNVPRCLHFSG-VG-KVRQAACGGTGCA 349
Query: 795 VLSKSGAVFGWGKNTHGXLG 854
VL+ G VF WG +G LG
Sbjct: 350 VLNGEGHVFVWG---YGILG 366
Score = 79.4 bits (187), Expect = 2e-14
Identities = 57/196 (29%), Positives = 83/196 (42%), Gaps = 8/196 (4%)
Frame = +3
Query: 291 VAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQH 470
VA G+ HSL+L++ G +YSCG GQ G + L + +A
Sbjct: 235 VACGQDHSLFLTDKGEVYSCGWGADGQTGLGHYNITSSPTKLGGDLAGVNVIQVATYGDC 294
Query: 471 SLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNS 650
LA+ G F WG+ QL + + + P+ + V Q ACG L
Sbjct: 295 CLAVSADGGLFGWGNSEYLQLASVTDSTQVNVPRCLHFSGVGKVRQAACGGTGCAVLNGE 354
Query: 651 GDLYSWGANSYGQCGLGTISNKEMSPQHIS-SLIG-------VPIALIACGNNHTFVLSK 806
G ++ WG YG G G + P+ I +L G + ++ I CG +H L+
Sbjct: 355 GHVFVWG---YGILGKGPNLVESAVPEMIPPTLFGLTEFNPEIQVSRIRCGLSHFAALTN 411
Query: 807 SGAVFGWGKNTHGXLG 854
G +F WGKN G LG
Sbjct: 412 KGELFVWGKNIRGCLG 427
Score = 60.9 bits (141), Expect = 6e-09
Identities = 46/151 (30%), Positives = 68/151 (45%), Gaps = 6/151 (3%)
Frame = +3
Query: 282 IQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACG 461
IQ G+ L +S G L+ GN++ QL T+S P + + ACG
Sbjct: 286 IQVATYGDC-CLAVSADGGLFGWGNSEYLQLASVTDSTQVNVPRCLHFSGVGKVRQAACG 344
Query: 462 LQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDK--PKFVKGLATKN----VIQVACGA 623
++ G F WG +G+ G NL A + P + GL N V ++ CG
Sbjct: 345 GTGCAVLNGEGHVFVWGYGILGK-GPNLVESAVPEMIPPTLFGLTEFNPEIQVSRIRCGL 403
Query: 624 YHSVALTNSGDLYSWGANSYGQCGLGTISNK 716
H ALTN G+L+ WG N G G+G + ++
Sbjct: 404 SHFAALTNKGELFVWGKNIRGCLGIGRLEDQ 434
>BC019008-1|AAH19008.1| 464|Homo sapiens Williams-Beuren syndrome
chromosome region 16 protein.
Length = 464
Score = 82.6 bits (195), Expect = 2e-15
Identities = 64/200 (32%), Positives = 93/200 (46%), Gaps = 5/200 (2%)
Frame = +3
Query: 270 ESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQ-TESDNGKNPALVETFKDC--T 440
+ + V+ G HSL L++ ++S GNN GQ GR+ E++ V +D
Sbjct: 172 QETRVLQVSCGRAHSLVLTDREGVFSMGNNSYGQCGRKVVENEIYSESHRVHRMQDFDGQ 231
Query: 441 ISTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACG 620
+ +ACG HSL + + G+ +S G + GQ G K LA NVIQVA
Sbjct: 232 VVQVACGQDHSLFLTDKGEVYSCGWGADGQTGLGHYNITSSPTKLGGDLAGVNVIQVATY 291
Query: 621 AYHSVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQ--HISSLIGVPIALIACGNNHTF 794
+A++ G L+ WG + Y Q T S + P+ H S +G + ACG
Sbjct: 292 GDCCLAVSADGGLFGWGNSEYLQLASVTDSTQVNVPRCLHFSG-VG-KVRQAACGGTGCA 349
Query: 795 VLSKSGAVFGWGKNTHGXLG 854
VL+ G VF WG +G LG
Sbjct: 350 VLNGEGHVFVWG---YGILG 366
Score = 79.4 bits (187), Expect = 2e-14
Identities = 57/196 (29%), Positives = 83/196 (42%), Gaps = 8/196 (4%)
Frame = +3
Query: 291 VAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQH 470
VA G+ HSL+L++ G +YSCG GQ G + L + +A
Sbjct: 235 VACGQDHSLFLTDKGEVYSCGWGADGQTGLGHYNITSSPTKLGGDLAGVNVIQVATYGDC 294
Query: 471 SLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNS 650
LA+ G F WG+ QL + + + P+ + V Q ACG L
Sbjct: 295 CLAVSADGGLFGWGNSEYLQLASVTDSTQVNVPRCLHFSGVGKVRQAACGGTGCAVLNGE 354
Query: 651 GDLYSWGANSYGQCGLGTISNKEMSPQHIS-SLIG-------VPIALIACGNNHTFVLSK 806
G ++ WG YG G G + P+ I +L G + ++ I CG +H L+
Sbjct: 355 GHVFVWG---YGILGKGPNLVESAVPEMIPPTLFGLTEFNPEIQVSRIRCGLSHFAALTN 411
Query: 807 SGAVFGWGKNTHGXLG 854
G +F WGKN G LG
Sbjct: 412 KGELFVWGKNIRGCLG 427
Score = 70.9 bits (166), Expect = 5e-12
Identities = 56/182 (30%), Positives = 85/182 (46%), Gaps = 6/182 (3%)
Frame = +3
Query: 282 IQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACG 461
IQ G+ L +S G L+ GN++ QL T+S P + + ACG
Sbjct: 286 IQVATYGDC-CLAVSADGGLFGWGNSEYLQLASVTDSTQVNVPRCLHFSGVGKVRQAACG 344
Query: 462 LQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDK--PKFVKGLATKN----VIQVACGA 623
++ G F WG +G+ G NL A + P + GL N V ++ CG
Sbjct: 345 GTGCAVLNGEGHVFVWGYGILGK-GPNLVESAVPEMIPPTLFGLTEFNPEIQVSRIRCGL 403
Query: 624 YHSVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFVLS 803
H ALTN G+L+ WG N G G+G + + + P + ++ G P+ +ACG +H L+
Sbjct: 404 SHFAALTNKGELFVWGKNIRGCLGIGRLED-QYFPWRV-TMPGEPVD-VACGVDHMVTLA 460
Query: 804 KS 809
KS
Sbjct: 461 KS 462
>BC007823-1|AAH07823.1| 464|Homo sapiens Williams-Beuren syndrome
chromosome region 16 protein.
Length = 464
Score = 82.6 bits (195), Expect = 2e-15
Identities = 64/200 (32%), Positives = 93/200 (46%), Gaps = 5/200 (2%)
Frame = +3
Query: 270 ESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQ-TESDNGKNPALVETFKDC--T 440
+ + V+ G HSL L++ ++S GNN GQ GR+ E++ V +D
Sbjct: 172 QETRVLQVSCGRAHSLVLTDREGVFSMGNNSYGQCGRKVVENEIYSESHRVHRMQDFDGQ 231
Query: 441 ISTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACG 620
+ +ACG HSL + + G+ +S G + GQ G K LA NVIQVA
Sbjct: 232 VVQVACGQDHSLFLTDKGEVYSCGWGADGQTGLGHYNITSSPTKLGGDLAGVNVIQVATY 291
Query: 621 AYHSVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQ--HISSLIGVPIALIACGNNHTF 794
+A++ G L+ WG + Y Q T S + P+ H S +G + ACG
Sbjct: 292 GDCCLAVSADGGLFGWGNSEYLQLASVTDSTQVNVPRCLHFSG-VG-KVRQAACGGTGCA 349
Query: 795 VLSKSGAVFGWGKNTHGXLG 854
VL+ G VF WG +G LG
Sbjct: 350 VLNGEGHVFVWG---YGILG 366
Score = 79.4 bits (187), Expect = 2e-14
Identities = 57/196 (29%), Positives = 83/196 (42%), Gaps = 8/196 (4%)
Frame = +3
Query: 291 VAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQH 470
VA G+ HSL+L++ G +YSCG GQ G + L + +A
Sbjct: 235 VACGQDHSLFLTDKGEVYSCGWGADGQTGLGHYNITSSPTKLGGDLAGVNVIQVATYGDC 294
Query: 471 SLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNS 650
LA+ G F WG+ QL + + + P+ + V Q ACG L
Sbjct: 295 CLAVSADGGLFGWGNSEYLQLASVTDSTQVNVPRCLHFSGVGKVRQAACGGTGCAVLNGE 354
Query: 651 GDLYSWGANSYGQCGLGTISNKEMSPQHIS-SLIG-------VPIALIACGNNHTFVLSK 806
G ++ WG YG G G + P+ I +L G + ++ I CG +H L+
Sbjct: 355 GHVFVWG---YGILGKGPNLVESAVPEMIPPTLFGLTEFNPEIQVSRIRCGLSHFAALTN 411
Query: 807 SGAVFGWGKNTHGXLG 854
G +F WGKN G LG
Sbjct: 412 KGELFVWGKNIRGCLG 427
Score = 70.9 bits (166), Expect = 5e-12
Identities = 56/182 (30%), Positives = 85/182 (46%), Gaps = 6/182 (3%)
Frame = +3
Query: 282 IQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACG 461
IQ G+ L +S G L+ GN++ QL T+S P + + ACG
Sbjct: 286 IQVATYGDC-CLAVSADGGLFGWGNSEYLQLASVTDSTQVNVPRCLHFSGVGKVRQAACG 344
Query: 462 LQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDK--PKFVKGLATKN----VIQVACGA 623
++ G F WG +G+ G NL A + P + GL N V ++ CG
Sbjct: 345 GTGCAVLNGEGHVFVWGYGILGK-GPNLVESAVPEMIPPTLFGLTEFNPEIQVSRIRCGL 403
Query: 624 YHSVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFVLS 803
H ALTN G+L+ WG N G G+G + + + P + ++ G P+ +ACG +H L+
Sbjct: 404 SHFAALTNKGELFVWGKNIRGCLGIGRLED-QYFPWRV-TMPGEPVD-VACGVDHMVTLA 460
Query: 804 KS 809
KS
Sbjct: 461 KS 462
>AF410455-1|AAM62304.1| 464|Homo sapiens RCC1-like G exchanging
factor-like protein protein.
Length = 464
Score = 82.6 bits (195), Expect = 2e-15
Identities = 64/200 (32%), Positives = 93/200 (46%), Gaps = 5/200 (2%)
Frame = +3
Query: 270 ESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQ-TESDNGKNPALVETFKDC--T 440
+ + V+ G HSL L++ ++S GNN GQ GR+ E++ V +D
Sbjct: 172 QETRVLQVSCGRAHSLVLTDREGVFSMGNNSYGQCGRKVVENEIYSESHRVHRMQDFDGQ 231
Query: 441 ISTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACG 620
+ +ACG HSL + + G+ +S G + GQ G K LA NVIQVA
Sbjct: 232 VVQVACGQDHSLFLTDKGEVYSCGWGADGQTGLGHYNITSSPTKLGGDLAGVNVIQVATY 291
Query: 621 AYHSVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQ--HISSLIGVPIALIACGNNHTF 794
+A++ G L+ WG + Y Q T S + P+ H S +G + ACG
Sbjct: 292 GDCCLAVSADGGLFGWGNSEYLQLASVTDSTQVNVPRCLHFSG-VG-KVRQAACGGTGCA 349
Query: 795 VLSKSGAVFGWGKNTHGXLG 854
VL+ G VF WG +G LG
Sbjct: 350 VLNGEGHVFVWG---YGILG 366
Score = 79.4 bits (187), Expect = 2e-14
Identities = 57/196 (29%), Positives = 83/196 (42%), Gaps = 8/196 (4%)
Frame = +3
Query: 291 VAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQH 470
VA G+ HSL+L++ G +YSCG GQ G + L + +A
Sbjct: 235 VACGQDHSLFLTDKGEVYSCGWGADGQTGLGHYNITSSPTKLGGDLAGVNVIQVATYGDC 294
Query: 471 SLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNS 650
LA+ G F WG+ QL + + + P+ + V Q ACG L
Sbjct: 295 CLAVSADGGLFGWGNSEYLQLASVTDSTQVNVPRCLHFSGVGKVRQAACGGTGCAVLNGE 354
Query: 651 GDLYSWGANSYGQCGLGTISNKEMSPQHIS-SLIG-------VPIALIACGNNHTFVLSK 806
G ++ WG YG G G + P+ I +L G + ++ I CG +H L+
Sbjct: 355 GHVFVWG---YGILGKGPNLVESAVPEMIPPTLFGLTEFNPEIQVSRIRCGLSHFAALTN 411
Query: 807 SGAVFGWGKNTHGXLG 854
G +F WGKN G LG
Sbjct: 412 KGELFVWGKNIRGCLG 427
Score = 70.9 bits (166), Expect = 5e-12
Identities = 56/182 (30%), Positives = 85/182 (46%), Gaps = 6/182 (3%)
Frame = +3
Query: 282 IQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACG 461
IQ G+ L +S G L+ GN++ QL T+S P + + ACG
Sbjct: 286 IQVATYGDC-CLAVSADGGLFGWGNSEYLQLASVTDSTQVNVPRCLHFSGVGKVRQAACG 344
Query: 462 LQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDK--PKFVKGLATKN----VIQVACGA 623
++ G F WG +G+ G NL A + P + GL N V ++ CG
Sbjct: 345 GTGCAVLNGEGHVFVWGYGILGK-GPNLVESAVPEMIPPTLFGLTEFNPEIQVSRIRCGL 403
Query: 624 YHSVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFVLS 803
H ALTN G+L+ WG N G G+G + + + P + ++ G P+ +ACG +H L+
Sbjct: 404 SHFAALTNKGELFVWGKNIRGCLGIGRLED-QYFPWRV-TMPGEPVD-VACGVDHMVTLA 460
Query: 804 KS 809
KS
Sbjct: 461 KS 462
>BC040929-1|AAH40929.1| 651|Homo sapiens HERC1 protein protein.
Length = 651
Score = 81.0 bits (191), Expect = 5e-15
Identities = 47/147 (31%), Positives = 79/147 (53%)
Frame = +3
Query: 351 GNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQ 530
G+ D G+LG + +P ++ I +ACG Q S+A+ + G +++G D +
Sbjct: 2 GDGDYGKLGLGNSTAKS-SPQKIDVLCGIGIKKVACGTQFSVALTKDGHVYTFGQDRLIG 60
Query: 531 LGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTIS 710
L A ++P+ + LA + VA GA H++AL ++GD+Y+WG+NS GQ GLG +
Sbjct: 61 LPEGR-ARNHNRPQQIPVLAGVIIEDVAVGAEHTLALASNGDVYAWGSNSEGQLGLGH-T 118
Query: 711 NKEMSPQHISSLIGVPIALIACGNNHT 791
N P ++ L G + I+ G H+
Sbjct: 119 NHVREPTLVTGLQGKNVRQISAGRCHS 145
Score = 72.1 bits (169), Expect = 2e-12
Identities = 42/121 (34%), Positives = 63/121 (52%)
Frame = +3
Query: 282 IQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACG 461
I+ VA G S+ L+ GH+Y+ G + + L + + N P + I +A G
Sbjct: 31 IKKVACGTQFSVALTKDGHVYTFGQDRLIGLP-EGRARNHNRPQQIPVLAGVIIEDVAVG 89
Query: 462 LQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVAL 641
+H+LA+ G ++WGS+S GQLG H ++ P V GL KNV Q++ G HS A
Sbjct: 90 AEHTLALASNGDVYAWGSNSEGQLGLGHTNHVRE-PTLVTGLQGKNVRQISAGRCHSAAW 148
Query: 642 T 644
T
Sbjct: 149 T 149
Score = 69.3 bits (162), Expect = 2e-11
Identities = 41/116 (35%), Positives = 58/116 (50%)
Frame = +3
Query: 507 WGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYG 686
+G G+LG + A+ P+ + L + +VACG SVALT G +Y++G +
Sbjct: 1 FGDGDYGKLGLG-NSTAKSSPQKIDVLCGIGIKKVACGTQFSVALTKDGHVYTFGQDRLI 59
Query: 687 QCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFVLSKSGAVFGWGKNTHGXLG 854
G N PQ I L GV I +A G HT L+ +G V+ WG N+ G LG
Sbjct: 60 GLPEGRARNHNR-PQQIPVLAGVIIEDVAVGAEHTLALASNGDVYAWGSNSEGQLG 114
>DQ005634-1|AAY55907.1| 1196|Homo sapiens inhibitor of Bruton's
tyrosine kinase-beta protein.
Length = 1196
Score = 72.5 bits (170), Expect = 2e-12
Identities = 54/191 (28%), Positives = 95/191 (49%), Gaps = 10/191 (5%)
Frame = +3
Query: 279 HIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIAC 458
+I+ V +FHS++LS G +Y+CG+ G+LG E P LVE S +A
Sbjct: 178 YIKQVVLCKFHSVFLSQKGQVYTCGHGPGGRLGHGDE-QTCLVPRLVEGLNGHNCSQVAA 236
Query: 459 GLQHSLAIDEWGQPFSWGSDSMGQLG-----NNLGAHAQDKPKFVKGLATKNVIQVACGA 623
H++ + E G +++G + QLG ++ Q + K++KG + +I VA G
Sbjct: 237 AKDHTVVLTEDGCVYTFGLNIFHQLGIIPPPSSCNVPRQIQAKYLKG---RTIIGVAAGR 293
Query: 624 YHSVALTNSGDLYSWGANSYGQCGLGTISNKE---MSPQHISSL--IGVPIALIACGNNH 788
+H+V T +Y+ G N GQ G N E +P+ +S+L + ++L+A +
Sbjct: 294 FHTVLWTREA-VYTMGLNG-GQLGCLLDPNGEKCVTAPRQVSALHHKDIALSLVAASDGA 351
Query: 789 TFVLSKSGAVF 821
T ++ G ++
Sbjct: 352 TVCVTTRGDIY 362
Score = 61.3 bits (142), Expect = 4e-09
Identities = 55/177 (31%), Positives = 84/177 (47%), Gaps = 5/177 (2%)
Frame = +3
Query: 339 LYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTI---STIACGLQHSLAIDEWGQPFSW 509
+Y+ G+N LG +++ +P LV+ F I + C HS+ + + GQ ++
Sbjct: 144 VYTWGDNTNFTLGHGSQNSK-HHPELVDLFSRSGIYIKQVVLCKF-HSVFLSQKGQVYTC 201
Query: 510 GSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQ 689
G G+LG+ P+ V+GL N QVA H+V LT G +Y++G N + Q
Sbjct: 202 GHGPGGRLGHG-DEQTCLVPRLVEGLNGHNCSQVAAAKDHTVVLTEDGCVYTFGLNIFHQ 260
Query: 690 CGLGTISNKEMSPQHISS--LIGVPIALIACGNNHTFVLSKSGAVFGWGKNTHGXLG 854
G+ + P+ I + L G I +A G HT VL AV+ G N G LG
Sbjct: 261 LGIIPPPSSCNVPRQIQAKYLKGRTIIGVAAGRFHT-VLWTREAVYTMGLN-GGQLG 315
Score = 35.9 bits (79), Expect = 0.19
Identities = 41/153 (26%), Positives = 63/153 (41%), Gaps = 5/153 (3%)
Frame = +3
Query: 219 GSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDN 398
G + T LV P L + + VAA + H++ L+ G +Y+ G N QLG +
Sbjct: 212 GDEQTCLV--PRLVEGLNGHNCSQVAAAKDHTVVLTEDGCVYTFGLNIFHQLGIIPPPSS 269
Query: 399 GKNPALVET--FKDCTISTIACGLQHS-LAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKP 569
P ++ K TI +A G H+ L E +G L + G P
Sbjct: 270 CNVPRQIQAKYLKGRTIIGVAAGRFHTVLWTREAVYTMGLNGGQLGCLLDPNGEKCVTAP 329
Query: 570 KFVKGLATKNVI--QVACGAYHSVALTNSGDLY 662
+ V L K++ VA +V +T GD+Y
Sbjct: 330 RQVSALHHKDIALSLVAASDGATVCVTTRGDIY 362
Score = 35.1 bits (77), Expect = 0.33
Identities = 28/110 (25%), Positives = 50/110 (45%), Gaps = 2/110 (1%)
Frame = +3
Query: 531 LGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTIS 710
L + + + QDK +GL+ +++ + T+ D+Y+WG N+ G G+
Sbjct: 106 LKHGVSLYIQDK----EGLSALDLVMKDRPTHVVFKNTDPTDVYTWGDNTNFTLGHGS-Q 160
Query: 711 NKEMSPQHIS--SLIGVPIALIACGNNHTFVLSKSGAVFGWGKNTHGXLG 854
N + P+ + S G+ I + H+ LS+ G V+ G G LG
Sbjct: 161 NSKHHPELVDLFSRSGIYIKQVVLCKFHSVFLSQKGQVYTCGHGPGGRLG 210
>DQ005633-1|AAY55906.1| 1353|Homo sapiens inhibitor of Bruton's
tyrosine kinase-alpha protein.
Length = 1353
Score = 72.5 bits (170), Expect = 2e-12
Identities = 54/191 (28%), Positives = 95/191 (49%), Gaps = 10/191 (5%)
Frame = +3
Query: 279 HIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIAC 458
+I+ V +FHS++LS G +Y+CG+ G+LG E P LVE S +A
Sbjct: 178 YIKQVVLCKFHSVFLSQKGQVYTCGHGPGGRLGHGDE-QTCLVPRLVEGLNGHNCSQVAA 236
Query: 459 GLQHSLAIDEWGQPFSWGSDSMGQLG-----NNLGAHAQDKPKFVKGLATKNVIQVACGA 623
H++ + E G +++G + QLG ++ Q + K++KG + +I VA G
Sbjct: 237 AKDHTVVLTEDGCVYTFGLNIFHQLGIIPPPSSCNVPRQIQAKYLKG---RTIIGVAAGR 293
Query: 624 YHSVALTNSGDLYSWGANSYGQCGLGTISNKE---MSPQHISSL--IGVPIALIACGNNH 788
+H+V T +Y+ G N GQ G N E +P+ +S+L + ++L+A +
Sbjct: 294 FHTVLWTREA-VYTMGLNG-GQLGCLLDPNGEKCVTAPRQVSALHHKDIALSLVAASDGA 351
Query: 789 TFVLSKSGAVF 821
T ++ G ++
Sbjct: 352 TVCVTTRGDIY 362
Score = 61.3 bits (142), Expect = 4e-09
Identities = 55/177 (31%), Positives = 84/177 (47%), Gaps = 5/177 (2%)
Frame = +3
Query: 339 LYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTI---STIACGLQHSLAIDEWGQPFSW 509
+Y+ G+N LG +++ +P LV+ F I + C HS+ + + GQ ++
Sbjct: 144 VYTWGDNTNFTLGHGSQNSK-HHPELVDLFSRSGIYIKQVVLCKF-HSVFLSQKGQVYTC 201
Query: 510 GSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQ 689
G G+LG+ P+ V+GL N QVA H+V LT G +Y++G N + Q
Sbjct: 202 GHGPGGRLGHG-DEQTCLVPRLVEGLNGHNCSQVAAAKDHTVVLTEDGCVYTFGLNIFHQ 260
Query: 690 CGLGTISNKEMSPQHISS--LIGVPIALIACGNNHTFVLSKSGAVFGWGKNTHGXLG 854
G+ + P+ I + L G I +A G HT VL AV+ G N G LG
Sbjct: 261 LGIIPPPSSCNVPRQIQAKYLKGRTIIGVAAGRFHT-VLWTREAVYTMGLN-GGQLG 315
Score = 35.9 bits (79), Expect = 0.19
Identities = 41/153 (26%), Positives = 63/153 (41%), Gaps = 5/153 (3%)
Frame = +3
Query: 219 GSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDN 398
G + T LV P L + + VAA + H++ L+ G +Y+ G N QLG +
Sbjct: 212 GDEQTCLV--PRLVEGLNGHNCSQVAAAKDHTVVLTEDGCVYTFGLNIFHQLGIIPPPSS 269
Query: 399 GKNPALVET--FKDCTISTIACGLQHS-LAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKP 569
P ++ K TI +A G H+ L E +G L + G P
Sbjct: 270 CNVPRQIQAKYLKGRTIIGVAAGRFHTVLWTREAVYTMGLNGGQLGCLLDPNGEKCVTAP 329
Query: 570 KFVKGLATKNVI--QVACGAYHSVALTNSGDLY 662
+ V L K++ VA +V +T GD+Y
Sbjct: 330 RQVSALHHKDIALSLVAASDGATVCVTTRGDIY 362
Score = 35.1 bits (77), Expect = 0.33
Identities = 28/110 (25%), Positives = 50/110 (45%), Gaps = 2/110 (1%)
Frame = +3
Query: 531 LGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTIS 710
L + + + QDK +GL+ +++ + T+ D+Y+WG N+ G G+
Sbjct: 106 LKHGVSLYIQDK----EGLSALDLVMKDRPTHVVFKNTDPTDVYTWGDNTNFTLGHGS-Q 160
Query: 711 NKEMSPQHIS--SLIGVPIALIACGNNHTFVLSKSGAVFGWGKNTHGXLG 854
N + P+ + S G+ I + H+ LS+ G V+ G G LG
Sbjct: 161 NSKHHPELVDLFSRSGIYIKQVVLCKFHSVFLSQKGQVYTCGHGPGGRLG 210
>BC113698-1|AAI13699.1| 1353|Homo sapiens inhibitor of Bruton
agammaglobulinemia tyrosine kinase protein.
Length = 1353
Score = 72.5 bits (170), Expect = 2e-12
Identities = 54/191 (28%), Positives = 95/191 (49%), Gaps = 10/191 (5%)
Frame = +3
Query: 279 HIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIAC 458
+I+ V +FHS++LS G +Y+CG+ G+LG E P LVE S +A
Sbjct: 178 YIKQVVLCKFHSVFLSQKGQVYTCGHGPGGRLGHGDE-QTCLVPRLVEGLNGHNCSQVAA 236
Query: 459 GLQHSLAIDEWGQPFSWGSDSMGQLG-----NNLGAHAQDKPKFVKGLATKNVIQVACGA 623
H++ + E G +++G + QLG ++ Q + K++KG + +I VA G
Sbjct: 237 AKDHTVVLTEDGCVYTFGLNIFHQLGIIPPPSSCNVPRQIQAKYLKG---RTIIGVAAGR 293
Query: 624 YHSVALTNSGDLYSWGANSYGQCGLGTISNKE---MSPQHISSL--IGVPIALIACGNNH 788
+H+V T +Y+ G N GQ G N E +P+ +S+L + ++L+A +
Sbjct: 294 FHTVLWTREA-VYTMGLNG-GQLGCLLDPNGEKCVTAPRQVSALHHKDIALSLVAASDGA 351
Query: 789 TFVLSKSGAVF 821
T ++ G ++
Sbjct: 352 TVCVTTRGDIY 362
Score = 61.3 bits (142), Expect = 4e-09
Identities = 55/177 (31%), Positives = 84/177 (47%), Gaps = 5/177 (2%)
Frame = +3
Query: 339 LYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTI---STIACGLQHSLAIDEWGQPFSW 509
+Y+ G+N LG +++ +P LV+ F I + C HS+ + + GQ ++
Sbjct: 144 VYTWGDNTNFTLGHGSQNSK-HHPELVDLFSRSGIYIKQVVLCKF-HSVFLSQKGQVYTC 201
Query: 510 GSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQ 689
G G+LG+ P+ V+GL N QVA H+V LT G +Y++G N + Q
Sbjct: 202 GHGPGGRLGHG-DEQTCLVPRLVEGLNGHNCSQVAAAKDHTVVLTEDGCVYTFGLNIFHQ 260
Query: 690 CGLGTISNKEMSPQHISS--LIGVPIALIACGNNHTFVLSKSGAVFGWGKNTHGXLG 854
G+ + P+ I + L G I +A G HT VL AV+ G N G LG
Sbjct: 261 LGIIPPPSSCNVPRQIQAKYLKGRTIIGVAAGRFHT-VLWTREAVYTMGLN-GGQLG 315
Score = 35.9 bits (79), Expect = 0.19
Identities = 41/153 (26%), Positives = 63/153 (41%), Gaps = 5/153 (3%)
Frame = +3
Query: 219 GSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDN 398
G + T LV P L + + VAA + H++ L+ G +Y+ G N QLG +
Sbjct: 212 GDEQTCLV--PRLVEGLNGHNCSQVAAAKDHTVVLTEDGCVYTFGLNIFHQLGIIPPPSS 269
Query: 399 GKNPALVET--FKDCTISTIACGLQHS-LAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKP 569
P ++ K TI +A G H+ L E +G L + G P
Sbjct: 270 CNVPRQIQAKYLKGRTIIGVAAGRFHTVLWTREAVYTMGLNGGQLGCLLDPNGEKCVTAP 329
Query: 570 KFVKGLATKNVI--QVACGAYHSVALTNSGDLY 662
+ V L K++ VA +V +T GD+Y
Sbjct: 330 RQVSALHHKDIALSLVAASDGATVCVTTRGDIY 362
Score = 35.1 bits (77), Expect = 0.33
Identities = 28/110 (25%), Positives = 50/110 (45%), Gaps = 2/110 (1%)
Frame = +3
Query: 531 LGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTIS 710
L + + + QDK +GL+ +++ + T+ D+Y+WG N+ G G+
Sbjct: 106 LKHGVSLYIQDK----EGLSALDLVMKDRPTHVVFKNTDPTDVYTWGDNTNFTLGHGS-Q 160
Query: 711 NKEMSPQHIS--SLIGVPIALIACGNNHTFVLSKSGAVFGWGKNTHGXLG 854
N + P+ + S G+ I + H+ LS+ G V+ G G LG
Sbjct: 161 NSKHHPELVDLFSRSGIYIKQVVLCKFHSVFLSQKGQVYTCGHGPGGRLG 210
>BC113696-1|AAI13697.1| 1353|Homo sapiens inhibitor of Bruton
agammaglobulinemia tyrosine kinase protein.
Length = 1353
Score = 72.5 bits (170), Expect = 2e-12
Identities = 54/191 (28%), Positives = 95/191 (49%), Gaps = 10/191 (5%)
Frame = +3
Query: 279 HIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIAC 458
+I+ V +FHS++LS G +Y+CG+ G+LG E P LVE S +A
Sbjct: 178 YIKQVVLCKFHSVFLSQKGQVYTCGHGPGGRLGHGDE-QTCLVPRLVEGLNGHNCSQVAA 236
Query: 459 GLQHSLAIDEWGQPFSWGSDSMGQLG-----NNLGAHAQDKPKFVKGLATKNVIQVACGA 623
H++ + E G +++G + QLG ++ Q + K++KG + +I VA G
Sbjct: 237 AKDHTVVLTEDGCVYTFGLNIFHQLGIIPPPSSCNVPRQIQAKYLKG---RTIIGVAAGR 293
Query: 624 YHSVALTNSGDLYSWGANSYGQCGLGTISNKE---MSPQHISSL--IGVPIALIACGNNH 788
+H+V T +Y+ G N GQ G N E +P+ +S+L + ++L+A +
Sbjct: 294 FHTVLWTREA-VYTMGLNG-GQLGCLLDPNGEKCVTAPRQVSALHHKDIALSLVAASDGA 351
Query: 789 TFVLSKSGAVF 821
T ++ G ++
Sbjct: 352 TVCVTTRGDIY 362
Score = 61.3 bits (142), Expect = 4e-09
Identities = 55/177 (31%), Positives = 84/177 (47%), Gaps = 5/177 (2%)
Frame = +3
Query: 339 LYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTI---STIACGLQHSLAIDEWGQPFSW 509
+Y+ G+N LG +++ +P LV+ F I + C HS+ + + GQ ++
Sbjct: 144 VYTWGDNTNFTLGHGSQNSK-HHPELVDLFSRSGIYIKQVVLCKF-HSVFLSQKGQVYTC 201
Query: 510 GSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQ 689
G G+LG+ P+ V+GL N QVA H+V LT G +Y++G N + Q
Sbjct: 202 GHGPGGRLGHG-DEQTCLVPRLVEGLNGHNCSQVAAAKDHTVVLTEDGCVYTFGLNIFHQ 260
Query: 690 CGLGTISNKEMSPQHISS--LIGVPIALIACGNNHTFVLSKSGAVFGWGKNTHGXLG 854
G+ + P+ I + L G I +A G HT VL AV+ G N G LG
Sbjct: 261 LGIIPPPSSCNVPRQIQAKYLKGRTIIGVAAGRFHT-VLWTREAVYTMGLN-GGQLG 315
Score = 35.9 bits (79), Expect = 0.19
Identities = 41/153 (26%), Positives = 63/153 (41%), Gaps = 5/153 (3%)
Frame = +3
Query: 219 GSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDN 398
G + T LV P L + + VAA + H++ L+ G +Y+ G N QLG +
Sbjct: 212 GDEQTCLV--PRLVEGLNGHNCSQVAAAKDHTVVLTEDGCVYTFGLNIFHQLGIIPPPSS 269
Query: 399 GKNPALVET--FKDCTISTIACGLQHS-LAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKP 569
P ++ K TI +A G H+ L E +G L + G P
Sbjct: 270 CNVPRQIQAKYLKGRTIIGVAAGRFHTVLWTREAVYTMGLNGGQLGCLLDPNGEKCVTAP 329
Query: 570 KFVKGLATKNVI--QVACGAYHSVALTNSGDLY 662
+ V L K++ VA +V +T GD+Y
Sbjct: 330 RQVSALHHKDIALSLVAASDGATVCVTTRGDIY 362
Score = 35.1 bits (77), Expect = 0.33
Identities = 28/110 (25%), Positives = 50/110 (45%), Gaps = 2/110 (1%)
Frame = +3
Query: 531 LGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTIS 710
L + + + QDK +GL+ +++ + T+ D+Y+WG N+ G G+
Sbjct: 106 LKHGVSLYIQDK----EGLSALDLVMKDRPTHVVFKNTDPTDVYTWGDNTNFTLGHGS-Q 160
Query: 711 NKEMSPQHIS--SLIGVPIALIACGNNHTFVLSKSGAVFGWGKNTHGXLG 854
N + P+ + S G+ I + H+ LS+ G V+ G G LG
Sbjct: 161 NSKHHPELVDLFSRSGIYIKQVVLCKFHSVFLSQKGQVYTCGHGPGGRLG 210
>AL050333-2|CAI23416.1| 1187|Homo sapiens RP1-93K22.1 protein.
Length = 1187
Score = 72.5 bits (170), Expect = 2e-12
Identities = 54/191 (28%), Positives = 95/191 (49%), Gaps = 10/191 (5%)
Frame = +3
Query: 279 HIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIAC 458
+I+ V +FHS++LS G +Y+CG+ G+LG E P LVE S +A
Sbjct: 174 YIKQVVLCKFHSVFLSQKGQVYTCGHGPGGRLGHGDE-QTCLVPRLVEGLNGHNCSQVAA 232
Query: 459 GLQHSLAIDEWGQPFSWGSDSMGQLG-----NNLGAHAQDKPKFVKGLATKNVIQVACGA 623
H++ + E G +++G + QLG ++ Q + K++KG + +I VA G
Sbjct: 233 AKDHTVVLTEDGCVYTFGLNIFHQLGIIPPPSSCNVPRQIQAKYLKG---RTIIGVAAGR 289
Query: 624 YHSVALTNSGDLYSWGANSYGQCGLGTISNKE---MSPQHISSL--IGVPIALIACGNNH 788
+H+V T +Y+ G N GQ G N E +P+ +S+L + ++L+A +
Sbjct: 290 FHTVLWTREA-VYTMGLNG-GQLGCLLDPNGEKCVTAPRQVSALHHKDIALSLVAASDGA 347
Query: 789 TFVLSKSGAVF 821
T ++ G ++
Sbjct: 348 TVCVTTRGDIY 358
Score = 61.3 bits (142), Expect = 4e-09
Identities = 55/177 (31%), Positives = 84/177 (47%), Gaps = 5/177 (2%)
Frame = +3
Query: 339 LYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTI---STIACGLQHSLAIDEWGQPFSW 509
+Y+ G+N LG +++ +P LV+ F I + C HS+ + + GQ ++
Sbjct: 140 VYTWGDNTNFTLGHGSQNSK-HHPELVDLFSRSGIYIKQVVLCKF-HSVFLSQKGQVYTC 197
Query: 510 GSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQ 689
G G+LG+ P+ V+GL N QVA H+V LT G +Y++G N + Q
Sbjct: 198 GHGPGGRLGHG-DEQTCLVPRLVEGLNGHNCSQVAAAKDHTVVLTEDGCVYTFGLNIFHQ 256
Query: 690 CGLGTISNKEMSPQHISS--LIGVPIALIACGNNHTFVLSKSGAVFGWGKNTHGXLG 854
G+ + P+ I + L G I +A G HT VL AV+ G N G LG
Sbjct: 257 LGIIPPPSSCNVPRQIQAKYLKGRTIIGVAAGRFHT-VLWTREAVYTMGLN-GGQLG 311
Score = 35.9 bits (79), Expect = 0.19
Identities = 41/153 (26%), Positives = 63/153 (41%), Gaps = 5/153 (3%)
Frame = +3
Query: 219 GSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDN 398
G + T LV P L + + VAA + H++ L+ G +Y+ G N QLG +
Sbjct: 208 GDEQTCLV--PRLVEGLNGHNCSQVAAAKDHTVVLTEDGCVYTFGLNIFHQLGIIPPPSS 265
Query: 399 GKNPALVET--FKDCTISTIACGLQHS-LAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKP 569
P ++ K TI +A G H+ L E +G L + G P
Sbjct: 266 CNVPRQIQAKYLKGRTIIGVAAGRFHTVLWTREAVYTMGLNGGQLGCLLDPNGEKCVTAP 325
Query: 570 KFVKGLATKNVI--QVACGAYHSVALTNSGDLY 662
+ V L K++ VA +V +T GD+Y
Sbjct: 326 RQVSALHHKDIALSLVAASDGATVCVTTRGDIY 358
Score = 35.1 bits (77), Expect = 0.33
Identities = 28/110 (25%), Positives = 50/110 (45%), Gaps = 2/110 (1%)
Frame = +3
Query: 531 LGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTIS 710
L + + + QDK +GL+ +++ + T+ D+Y+WG N+ G G+
Sbjct: 102 LKHGVSLYIQDK----EGLSALDLVMKDRPTHVVFKNTDPTDVYTWGDNTNFTLGHGS-Q 156
Query: 711 NKEMSPQHIS--SLIGVPIALIACGNNHTFVLSKSGAVFGWGKNTHGXLG 854
N + P+ + S G+ I + H+ LS+ G V+ G G LG
Sbjct: 157 NSKHHPELVDLFSRSGIYIKQVVLCKFHSVFLSQKGQVYTCGHGPGGRLG 206
>AB037838-1|BAA92655.2| 1379|Homo sapiens KIAA1417 protein protein.
Length = 1379
Score = 72.5 bits (170), Expect = 2e-12
Identities = 54/191 (28%), Positives = 95/191 (49%), Gaps = 10/191 (5%)
Frame = +3
Query: 279 HIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIAC 458
+I+ V +FHS++LS G +Y+CG+ G+LG E P LVE S +A
Sbjct: 204 YIKQVVLCKFHSVFLSQKGQVYTCGHGPGGRLGHGDE-QTCLVPRLVEGLNGHNCSQVAA 262
Query: 459 GLQHSLAIDEWGQPFSWGSDSMGQLG-----NNLGAHAQDKPKFVKGLATKNVIQVACGA 623
H++ + E G +++G + QLG ++ Q + K++KG + +I VA G
Sbjct: 263 AKDHTVVLTEDGCVYTFGLNIFHQLGIIPPPSSCNVPRQIQAKYLKG---RTIIGVAAGR 319
Query: 624 YHSVALTNSGDLYSWGANSYGQCGLGTISNKE---MSPQHISSL--IGVPIALIACGNNH 788
+H+V T +Y+ G N GQ G N E +P+ +S+L + ++L+A +
Sbjct: 320 FHTVLWTREA-VYTMGLNG-GQLGCLLDPNGEKCVTAPRQVSALHHKDIALSLVAASDGA 377
Query: 789 TFVLSKSGAVF 821
T ++ G ++
Sbjct: 378 TVCVTTRGDIY 388
Score = 61.3 bits (142), Expect = 4e-09
Identities = 55/177 (31%), Positives = 84/177 (47%), Gaps = 5/177 (2%)
Frame = +3
Query: 339 LYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTI---STIACGLQHSLAIDEWGQPFSW 509
+Y+ G+N LG +++ +P LV+ F I + C HS+ + + GQ ++
Sbjct: 170 VYTWGDNTNFTLGHGSQNSK-HHPELVDLFSRSGIYIKQVVLCKF-HSVFLSQKGQVYTC 227
Query: 510 GSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQ 689
G G+LG+ P+ V+GL N QVA H+V LT G +Y++G N + Q
Sbjct: 228 GHGPGGRLGHG-DEQTCLVPRLVEGLNGHNCSQVAAAKDHTVVLTEDGCVYTFGLNIFHQ 286
Query: 690 CGLGTISNKEMSPQHISS--LIGVPIALIACGNNHTFVLSKSGAVFGWGKNTHGXLG 854
G+ + P+ I + L G I +A G HT VL AV+ G N G LG
Sbjct: 287 LGIIPPPSSCNVPRQIQAKYLKGRTIIGVAAGRFHT-VLWTREAVYTMGLN-GGQLG 341
Score = 35.9 bits (79), Expect = 0.19
Identities = 41/153 (26%), Positives = 63/153 (41%), Gaps = 5/153 (3%)
Frame = +3
Query: 219 GSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDN 398
G + T LV P L + + VAA + H++ L+ G +Y+ G N QLG +
Sbjct: 238 GDEQTCLV--PRLVEGLNGHNCSQVAAAKDHTVVLTEDGCVYTFGLNIFHQLGIIPPPSS 295
Query: 399 GKNPALVET--FKDCTISTIACGLQHS-LAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKP 569
P ++ K TI +A G H+ L E +G L + G P
Sbjct: 296 CNVPRQIQAKYLKGRTIIGVAAGRFHTVLWTREAVYTMGLNGGQLGCLLDPNGEKCVTAP 355
Query: 570 KFVKGLATKNVI--QVACGAYHSVALTNSGDLY 662
+ V L K++ VA +V +T GD+Y
Sbjct: 356 RQVSALHHKDIALSLVAASDGATVCVTTRGDIY 388
Score = 35.1 bits (77), Expect = 0.33
Identities = 28/110 (25%), Positives = 50/110 (45%), Gaps = 2/110 (1%)
Frame = +3
Query: 531 LGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTIS 710
L + + + QDK +GL+ +++ + T+ D+Y+WG N+ G G+
Sbjct: 132 LKHGVSLYIQDK----EGLSALDLVMKDRPTHVVFKNTDPTDVYTWGDNTNFTLGHGS-Q 186
Query: 711 NKEMSPQHIS--SLIGVPIALIACGNNHTFVLSKSGAVFGWGKNTHGXLG 854
N + P+ + S G+ I + H+ LS+ G V+ G G LG
Sbjct: 187 NSKHHPELVDLFSRSGIYIKQVVLCKFHSVFLSQKGQVYTCGHGPGGRLG 236
>BC040695-1|AAH40695.1| 358|Homo sapiens WBSCR16 protein protein.
Length = 358
Score = 71.3 bits (167), Expect = 4e-12
Identities = 56/183 (30%), Positives = 84/183 (45%), Gaps = 5/183 (2%)
Frame = +3
Query: 270 ESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQ-TESDNGKNPALVETFKDC--T 440
+ + V+ G HSL L++ ++S GNN GQ GR+ E++ V +D
Sbjct: 172 QETRVLQVSCGRAHSLVLTDREGVFSMGNNSYGQCGRKVVENEIYSESHRVHRMQDFDGQ 231
Query: 441 ISTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACG 620
+ +ACG HSL + + G+ +S G + GQ G K LA NVIQVA
Sbjct: 232 VVQVACGQDHSLFLTDKGEVYSCGWGADGQTGLGHYNITSSPTKLGGDLAGVNVIQVATY 291
Query: 621 AYHSVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQ--HISSLIGVPIALIACGNNHTF 794
+A++ G L+ WG + Y Q T S + P+ H S +G + ACG
Sbjct: 292 GDCCLAVSADGGLFGWGNSEYLQLASVTDSTQVNVPRCLHFSG-VG-KVRQAACGGTGCA 349
Query: 795 VLS 803
VL+
Sbjct: 350 VLN 352
Score = 71.3 bits (167), Expect = 4e-12
Identities = 45/142 (31%), Positives = 73/142 (51%), Gaps = 4/142 (2%)
Frame = +3
Query: 429 KDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHA-QDKPKFVKGLATKN-- 599
++ + ++CG HSL + + FS G++S GQ G + + + V + +
Sbjct: 172 QETRVLQVSCGRAHSLVLTDREGVFSMGNNSYGQCGRKVVENEIYSESHRVHRMQDFDGQ 231
Query: 600 VIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHI-SSLIGVPIALIAC 776
V+QVACG HS+ LT+ G++YS G + GQ GLG N SP + L GV + +A
Sbjct: 232 VVQVACGQDHSLFLTDKGEVYSCGWGADGQTGLGHY-NITSSPTKLGGDLAGVNVIQVAT 290
Query: 777 GNNHTFVLSKSGAVFGWGKNTH 842
+ +S G +FGWG + +
Sbjct: 291 YGDCCLAVSADGGLFGWGNSEY 312
Score = 46.8 bits (106), Expect = 1e-04
Identities = 32/120 (26%), Positives = 49/120 (40%)
Frame = +3
Query: 291 VAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQH 470
VA G+ HSL+L++ G +YSCG GQ G + L + +A
Sbjct: 235 VACGQDHSLFLTDKGEVYSCGWGADGQTGLGHYNITSSPTKLGGDLAGVNVIQVATYGDC 294
Query: 471 SLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNS 650
LA+ G F WG+ QL + + + P+ + V Q ACG L ++
Sbjct: 295 CLAVSADGGLFGWGNSEYLQLASVTDSTQVNVPRCLHFSGVGKVRQAACGGTGCAVLNDT 354
Score = 30.3 bits (65), Expect = 9.3
Identities = 11/29 (37%), Positives = 17/29 (58%)
Frame = +3
Query: 768 IACGNNHTFVLSKSGAVFGWGKNTHGXLG 854
++CG H+ VL+ VF G N++G G
Sbjct: 179 VSCGRAHSLVLTDREGVFSMGNNSYGQCG 207
>BC071576-1|AAH71576.1| 1237|Homo sapiens ALS2 protein protein.
Length = 1237
Score = 70.5 bits (165), Expect = 7e-12
Identities = 45/137 (32%), Positives = 67/137 (48%), Gaps = 6/137 (4%)
Frame = +3
Query: 438 TISTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVAC 617
T+ A G++H + + E G+ +S+G+ + P L + VI VA
Sbjct: 42 TVLQAALGVKHGVLLTEDGEVYSFGTLPWRSGPVEI---CPSSPILENALVGQYVITVAT 98
Query: 618 GAYHSVALTNSGDLYSWGANSYGQCGLGTISN-KEMSPQHI-----SSLIGVPIALIACG 779
G++HS A+T++G Y WG NS GQC + E +P I S L+ V I +ACG
Sbjct: 99 GSFHSGAVTDNGVAYMWGENSAGQCAVANQQYVPEPNPVSIADSEASPLLAVRILQLACG 158
Query: 780 NNHTFVLSKSGAVFGWG 830
HT LS S ++ WG
Sbjct: 159 EEHTLALSISREIWAWG 175
Score = 65.3 bits (152), Expect = 3e-10
Identities = 44/137 (32%), Positives = 69/137 (50%), Gaps = 6/137 (4%)
Frame = +3
Query: 249 PTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGK-NPALVET 425
P L ++ VA G FHS ++++G Y G N GQ + + NP +
Sbjct: 82 PILENALVGQYVITVATGSFHSGAVTDNGVAYMWGENSAGQCAVANQQYVPEPNPVSIAD 141
Query: 426 FKDCTISTI-----ACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLA 590
+ + + ACG +H+LA+ + ++WG+ QLG A KP+ V+ LA
Sbjct: 142 SEASPLLAVRILQLACGEEHTLALSISREIWAWGTGC--QLGLITTAFPVTKPQKVEHLA 199
Query: 591 TKNVIQVACGAYHSVAL 641
+ V+QVACGA+HS+AL
Sbjct: 200 GRVVLQVACGAFHSLAL 216
Score = 64.9 bits (151), Expect = 4e-10
Identities = 53/188 (28%), Positives = 83/188 (44%), Gaps = 6/188 (3%)
Frame = +3
Query: 255 LSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKD 434
L W +QA A G H + L+ G +YS G + G + +P L
Sbjct: 35 LPGWGGKTVLQA-ALGVKHGVLLTEDGEVYSFGTLP-WRSGPVEICPS--SPILENALVG 90
Query: 435 CTISTIACGLQHSLAIDEWGQPFSWGSDSMGQLG-NNLGAHAQDKPKFV-----KGLATK 596
+ T+A G HS A+ + G + WG +S GQ N + P + L
Sbjct: 91 QYVITVATGSFHSGAVTDNGVAYMWGENSAGQCAVANQQYVPEPNPVSIADSEASPLLAV 150
Query: 597 NVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIAC 776
++Q+ACG H++AL+ S ++++WG Q GL T + PQ + L G + +AC
Sbjct: 151 RILQLACGEEHTLALSISREIWAWGTGC--QLGLITTAFPVTKPQKVEHLAGRVVLQVAC 208
Query: 777 GNNHTFVL 800
G H+ L
Sbjct: 209 GAFHSLAL 216
Score = 62.9 bits (146), Expect = 1e-09
Identities = 45/121 (37%), Positives = 59/121 (48%)
Frame = +3
Query: 438 TISTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVAC 617
T S A L SL I+ W +WG GQLG+ + +P VK L K VI +
Sbjct: 512 TYSGEADALLPSLRIEVW----TWGKGKEGQLGHG-DVLPRLQPLCVKCLDGKEVIHLEA 566
Query: 618 GAYHSVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFV 797
G YHS+ALT +YSWG+N++GQ G ISS GV IA G +++
Sbjct: 567 GGYHSLALTAKSQVYSWGSNTFGQLGHSDFPTTVPRLAKISSENGV--WSIAAGRDYSLF 624
Query: 798 L 800
L
Sbjct: 625 L 625
Score = 54.0 bits (124), Expect = 7e-07
Identities = 28/93 (30%), Positives = 49/93 (52%)
Frame = +3
Query: 567 PKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSL 746
P+ + G K V+Q A G H V LT G++YS+G + G + SP ++L
Sbjct: 32 PERLPGWGGKTVLQAALGVKHGVLLTEDGEVYSFGTLPWRS---GPVEICPSSPILENAL 88
Query: 747 IGVPIALIACGNNHTFVLSKSGAVFGWGKNTHG 845
+G + +A G+ H+ ++ +G + WG+N+ G
Sbjct: 89 VGQYVITVATGSFHSGAVTDNGVAYMWGENSAG 121
Score = 45.6 bits (103), Expect = 2e-04
Identities = 20/67 (29%), Positives = 33/67 (49%)
Frame = +3
Query: 654 DLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFVLSKSGAVFGWGK 833
++++WG GQ G G + + + P + L G + + G H+ L+ V+ WG
Sbjct: 527 EVWTWGKGKEGQLGHGDVLPR-LQPLCVKCLDGKEVIHLEAGGYHSLALTAKSQVYSWGS 585
Query: 834 NTHGXLG 854
NT G LG
Sbjct: 586 NTFGQLG 592
Score = 44.4 bits (100), Expect = 5e-04
Identities = 33/120 (27%), Positives = 54/120 (45%)
Frame = +3
Query: 297 AGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSL 476
+GE +L S +++ G GQLG P V+ + + G HSL
Sbjct: 514 SGEADALLPSLRIEVWTWGKGKEGQLGHGDVLPR-LQPLCVKCLDGKEVIHLEAGGYHSL 572
Query: 477 AIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGD 656
A+ Q +SWGS++ GQLG++ P+ K + V +A G +S+ L ++ D
Sbjct: 573 ALTAKSQVYSWGSNTFGQLGHS--DFPTTVPRLAKISSENGVWSIAAGRDYSLFLVDTED 630
Score = 37.1 bits (82), Expect = 0.081
Identities = 23/78 (29%), Positives = 37/78 (47%)
Frame = +3
Query: 243 IKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVE 422
++P K + + + AG +HSL L+ +YS G+N GQLG P L +
Sbjct: 548 LQPLCVKCLDGKEVIHLEAGGYHSLALTAKSQVYSWGSNTFGQLGHSDFPTT--VPRLAK 605
Query: 423 TFKDCTISTIACGLQHSL 476
+ + +IA G +SL
Sbjct: 606 ISSENGVWSIAAGRDYSL 623
>AK023024-1|BAB14362.1| 396|Homo sapiens protein ( Homo sapiens
cDNA FLJ12962 fis, clone NT2RP2005694, weakly similar to
X-LINKED RETINITIS PIGMENTOSA GTPASE REGULATOR. ).
Length = 396
Score = 70.5 bits (165), Expect = 7e-12
Identities = 46/137 (33%), Positives = 69/137 (50%), Gaps = 6/137 (4%)
Frame = +3
Query: 438 TISTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVAC 617
T+ A G++H + + E G+ +S+G+ + + G P L + VI VA
Sbjct: 42 TVLQAALGVKHGVLLTEDGEVYSFGT-LLWRSGPV--EICPSSPILENALVGQYVITVAT 98
Query: 618 GAYHSVALTNSGDLYSWGANSYGQCGLGTISN-KEMSPQHI-----SSLIGVPIALIACG 779
G++HS A+T++G Y WG NS GQC + E +P I S L+ V I +ACG
Sbjct: 99 GSFHSGAVTDNGVAYMWGENSAGQCAVANQQYVPEPNPVSIADSEASPLLAVRILQLACG 158
Query: 780 NNHTFVLSKSGAVFGWG 830
HT LS S ++ WG
Sbjct: 159 EEHTLALSISREIWAWG 175
Score = 66.1 bits (154), Expect = 2e-10
Identities = 54/189 (28%), Positives = 83/189 (43%), Gaps = 7/189 (3%)
Frame = +3
Query: 255 LSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDN-GKNPALVETFK 431
L W +QA A G H + L+ G +YS G L R + +P L
Sbjct: 35 LPGWGGKTVLQA-ALGVKHGVLLTEDGEVYSFGT----LLWRSGPVEICPSSPILENALV 89
Query: 432 DCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQLG-NNLGAHAQDKPKFV-----KGLAT 593
+ T+A G HS A+ + G + WG +S GQ N + P + L
Sbjct: 90 GQYVITVATGSFHSGAVTDNGVAYMWGENSAGQCAVANQQYVPEPNPVSIADSEASPLLA 149
Query: 594 KNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIA 773
++Q+ACG H++AL+ S ++++WG Q GL T + PQ + L G + +A
Sbjct: 150 VRILQLACGEEHTLALSISREIWAWGTGC--QLGLITTAFPVTKPQKVEHLAGRVVLQVA 207
Query: 774 CGNNHTFVL 800
CG H+ L
Sbjct: 208 CGAFHSLAL 216
Score = 65.3 bits (152), Expect = 3e-10
Identities = 44/137 (32%), Positives = 69/137 (50%), Gaps = 6/137 (4%)
Frame = +3
Query: 249 PTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGK-NPALVET 425
P L ++ VA G FHS ++++G Y G N GQ + + NP +
Sbjct: 82 PILENALVGQYVITVATGSFHSGAVTDNGVAYMWGENSAGQCAVANQQYVPEPNPVSIAD 141
Query: 426 FKDCTISTI-----ACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLA 590
+ + + ACG +H+LA+ + ++WG+ QLG A KP+ V+ LA
Sbjct: 142 SEASPLLAVRILQLACGEEHTLALSISREIWAWGTGC--QLGLITTAFPVTKPQKVEHLA 199
Query: 591 TKNVIQVACGAYHSVAL 641
+ V+QVACGA+HS+AL
Sbjct: 200 GRVVLQVACGAFHSLAL 216
Score = 53.6 bits (123), Expect = 9e-07
Identities = 28/93 (30%), Positives = 49/93 (52%)
Frame = +3
Query: 567 PKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSL 746
P+ + G K V+Q A G H V LT G++YS+G + G + SP ++L
Sbjct: 32 PERLPGWGGKTVLQAALGVKHGVLLTEDGEVYSFGTLLWRS---GPVEICPSSPILENAL 88
Query: 747 IGVPIALIACGNNHTFVLSKSGAVFGWGKNTHG 845
+G + +A G+ H+ ++ +G + WG+N+ G
Sbjct: 89 VGQYVITVATGSFHSGAVTDNGVAYMWGENSAG 121
>AF391100-1|AAL14103.1| 1657|Homo sapiens alsin protein.
Length = 1657
Score = 70.5 bits (165), Expect = 7e-12
Identities = 46/137 (33%), Positives = 69/137 (50%), Gaps = 6/137 (4%)
Frame = +3
Query: 438 TISTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVAC 617
T+ A G++H + + E G+ +S+G+ + + G P L + VI VA
Sbjct: 42 TVLQAALGVKHGVLLTEDGEVYSFGT-LLWRSGPV--EICPSSPILENALVGQYVITVAT 98
Query: 618 GAYHSVALTNSGDLYSWGANSYGQCGLGTISN-KEMSPQHI-----SSLIGVPIALIACG 779
G++HS A+T++G Y WG NS GQC + E +P I S L+ V I +ACG
Sbjct: 99 GSFHSGAVTDNGVAYMWGENSAGQCAVANQQYVPEPNPVSIADSEASPLLAVRILQLACG 158
Query: 780 NNHTFVLSKSGAVFGWG 830
HT LS S ++ WG
Sbjct: 159 EEHTLALSISREIWAWG 175
Score = 66.1 bits (154), Expect = 2e-10
Identities = 54/189 (28%), Positives = 83/189 (43%), Gaps = 7/189 (3%)
Frame = +3
Query: 255 LSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDN-GKNPALVETFK 431
L W +QA A G H + L+ G +YS G L R + +P L
Sbjct: 35 LPGWGGKTVLQA-ALGVKHGVLLTEDGEVYSFGT----LLWRSGPVEICPSSPILENALV 89
Query: 432 DCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQLG-NNLGAHAQDKPKFV-----KGLAT 593
+ T+A G HS A+ + G + WG +S GQ N + P + L
Sbjct: 90 GQYVITVATGSFHSGAVTDNGVAYMWGENSAGQCAVANQQYVPEPNPVSIADSEASPLLA 149
Query: 594 KNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIA 773
++Q+ACG H++AL+ S ++++WG Q GL T + PQ + L G + +A
Sbjct: 150 VRILQLACGEEHTLALSISREIWAWGTGC--QLGLITTAFPVTKPQKVEHLAGRVVLQVA 207
Query: 774 CGNNHTFVL 800
CG H+ L
Sbjct: 208 CGAFHSLAL 216
Score = 65.3 bits (152), Expect = 3e-10
Identities = 44/137 (32%), Positives = 69/137 (50%), Gaps = 6/137 (4%)
Frame = +3
Query: 249 PTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGK-NPALVET 425
P L ++ VA G FHS ++++G Y G N GQ + + NP +
Sbjct: 82 PILENALVGQYVITVATGSFHSGAVTDNGVAYMWGENSAGQCAVANQQYVPEPNPVSIAD 141
Query: 426 FKDCTISTI-----ACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLA 590
+ + + ACG +H+LA+ + ++WG+ QLG A KP+ V+ LA
Sbjct: 142 SEASPLLAVRILQLACGEEHTLALSISREIWAWGTGC--QLGLITTAFPVTKPQKVEHLA 199
Query: 591 TKNVIQVACGAYHSVAL 641
+ V+QVACGA+HS+AL
Sbjct: 200 GRVVLQVACGAFHSLAL 216
Score = 60.9 bits (141), Expect = 6e-09
Identities = 44/121 (36%), Positives = 58/121 (47%)
Frame = +3
Query: 438 TISTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVAC 617
T S A L SL + W +WG GQLG+ + +P VK L K VI +
Sbjct: 512 TYSGEADALLPSLRTEVW----TWGKGKEGQLGHG-DVLPRLQPLCVKCLDGKEVIHLEA 566
Query: 618 GAYHSVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFV 797
G YHS+ALT +YSWG+N++GQ G ISS GV IA G +++
Sbjct: 567 GGYHSLALTAKSQVYSWGSNTFGQLGHSDFPTTVPRLAKISSENGV--WSIAAGRDYSLF 624
Query: 798 L 800
L
Sbjct: 625 L 625
Score = 53.6 bits (123), Expect = 9e-07
Identities = 28/93 (30%), Positives = 49/93 (52%)
Frame = +3
Query: 567 PKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSL 746
P+ + G K V+Q A G H V LT G++YS+G + G + SP ++L
Sbjct: 32 PERLPGWGGKTVLQAALGVKHGVLLTEDGEVYSFGTLLWRS---GPVEICPSSPILENAL 88
Query: 747 IGVPIALIACGNNHTFVLSKSGAVFGWGKNTHG 845
+G + +A G+ H+ ++ +G + WG+N+ G
Sbjct: 89 VGQYVITVATGSFHSGAVTDNGVAYMWGENSAG 121
Score = 45.6 bits (103), Expect = 2e-04
Identities = 20/67 (29%), Positives = 33/67 (49%)
Frame = +3
Query: 654 DLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFVLSKSGAVFGWGK 833
++++WG GQ G G + + + P + L G + + G H+ L+ V+ WG
Sbjct: 527 EVWTWGKGKEGQLGHGDVLPR-LQPLCVKCLDGKEVIHLEAGGYHSLALTAKSQVYSWGS 585
Query: 834 NTHGXLG 854
NT G LG
Sbjct: 586 NTFGQLG 592
Score = 45.2 bits (102), Expect = 3e-04
Identities = 33/120 (27%), Positives = 54/120 (45%)
Frame = +3
Query: 297 AGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSL 476
+GE +L S +++ G GQLG P V+ + + G HSL
Sbjct: 514 SGEADALLPSLRTEVWTWGKGKEGQLGHGDVLPR-LQPLCVKCLDGKEVIHLEAGGYHSL 572
Query: 477 AIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGD 656
A+ Q +SWGS++ GQLG++ P+ K + V +A G +S+ L ++ D
Sbjct: 573 ALTAKSQVYSWGSNTFGQLGHS--DFPTTVPRLAKISSENGVWSIAAGRDYSLFLVDTED 630
Score = 37.1 bits (82), Expect = 0.081
Identities = 23/78 (29%), Positives = 37/78 (47%)
Frame = +3
Query: 243 IKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVE 422
++P K + + + AG +HSL L+ +YS G+N GQLG P L +
Sbjct: 548 LQPLCVKCLDGKEVIHLEAGGYHSLALTAKSQVYSWGSNTFGQLGHSDFPTT--VPRLAK 605
Query: 423 TFKDCTISTIACGLQHSL 476
+ + +IA G +SL
Sbjct: 606 ISSENGVWSIAAGRDYSL 623
>AB053306-1|BAB69015.1| 396|Homo sapiens ALS2 protein.
Length = 396
Score = 70.5 bits (165), Expect = 7e-12
Identities = 45/137 (32%), Positives = 67/137 (48%), Gaps = 6/137 (4%)
Frame = +3
Query: 438 TISTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVAC 617
T+ A G++H + + E G+ +S+G+ + P L + VI VA
Sbjct: 42 TVLQAALGVKHGVLLTEDGEVYSFGTLPWRSGPVEI---CPSSPILENALVGQYVITVAT 98
Query: 618 GAYHSVALTNSGDLYSWGANSYGQCGLGTISN-KEMSPQHI-----SSLIGVPIALIACG 779
G++HS A+T++G Y WG NS GQC + E +P I S L+ V I +ACG
Sbjct: 99 GSFHSGAVTDNGVAYMWGENSAGQCAVANQQYVPEPNPVSIADSEASPLLAVRILQLACG 158
Query: 780 NNHTFVLSKSGAVFGWG 830
HT LS S ++ WG
Sbjct: 159 EEHTLALSISREIWAWG 175
Score = 65.3 bits (152), Expect = 3e-10
Identities = 44/137 (32%), Positives = 69/137 (50%), Gaps = 6/137 (4%)
Frame = +3
Query: 249 PTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGK-NPALVET 425
P L ++ VA G FHS ++++G Y G N GQ + + NP +
Sbjct: 82 PILENALVGQYVITVATGSFHSGAVTDNGVAYMWGENSAGQCAVANQQYVPEPNPVSIAD 141
Query: 426 FKDCTISTI-----ACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLA 590
+ + + ACG +H+LA+ + ++WG+ QLG A KP+ V+ LA
Sbjct: 142 SEASPLLAVRILQLACGEEHTLALSISREIWAWGTGC--QLGLITTAFPVTKPQKVEHLA 199
Query: 591 TKNVIQVACGAYHSVAL 641
+ V+QVACGA+HS+AL
Sbjct: 200 GRVVLQVACGAFHSLAL 216
Score = 64.9 bits (151), Expect = 4e-10
Identities = 53/188 (28%), Positives = 83/188 (44%), Gaps = 6/188 (3%)
Frame = +3
Query: 255 LSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKD 434
L W +QA A G H + L+ G +YS G + G + +P L
Sbjct: 35 LPGWGGKTVLQA-ALGVKHGVLLTEDGEVYSFGTLP-WRSGPVEICPS--SPILENALVG 90
Query: 435 CTISTIACGLQHSLAIDEWGQPFSWGSDSMGQLG-NNLGAHAQDKPKFV-----KGLATK 596
+ T+A G HS A+ + G + WG +S GQ N + P + L
Sbjct: 91 QYVITVATGSFHSGAVTDNGVAYMWGENSAGQCAVANQQYVPEPNPVSIADSEASPLLAV 150
Query: 597 NVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIAC 776
++Q+ACG H++AL+ S ++++WG Q GL T + PQ + L G + +AC
Sbjct: 151 RILQLACGEEHTLALSISREIWAWGTGC--QLGLITTAFPVTKPQKVEHLAGRVVLQVAC 208
Query: 777 GNNHTFVL 800
G H+ L
Sbjct: 209 GAFHSLAL 216
Score = 54.0 bits (124), Expect = 7e-07
Identities = 28/93 (30%), Positives = 49/93 (52%)
Frame = +3
Query: 567 PKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSL 746
P+ + G K V+Q A G H V LT G++YS+G + G + SP ++L
Sbjct: 32 PERLPGWGGKTVLQAALGVKHGVLLTEDGEVYSFGTLPWRS---GPVEICPSSPILENAL 88
Query: 747 IGVPIALIACGNNHTFVLSKSGAVFGWGKNTHG 845
+G + +A G+ H+ ++ +G + WG+N+ G
Sbjct: 89 VGQYVITVATGSFHSGAVTDNGVAYMWGENSAG 121
>AB053305-1|BAB69014.1| 1657|Homo sapiens ALS2 protein.
Length = 1657
Score = 70.5 bits (165), Expect = 7e-12
Identities = 45/137 (32%), Positives = 67/137 (48%), Gaps = 6/137 (4%)
Frame = +3
Query: 438 TISTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVAC 617
T+ A G++H + + E G+ +S+G+ + P L + VI VA
Sbjct: 42 TVLQAALGVKHGVLLTEDGEVYSFGTLPWRSGPVEI---CPSSPILENALVGQYVITVAT 98
Query: 618 GAYHSVALTNSGDLYSWGANSYGQCGLGTISN-KEMSPQHI-----SSLIGVPIALIACG 779
G++HS A+T++G Y WG NS GQC + E +P I S L+ V I +ACG
Sbjct: 99 GSFHSGAVTDNGVAYMWGENSAGQCAVANQQYVPEPNPVSIADSEASPLLAVRILQLACG 158
Query: 780 NNHTFVLSKSGAVFGWG 830
HT LS S ++ WG
Sbjct: 159 EEHTLALSISREIWAWG 175
Score = 65.3 bits (152), Expect = 3e-10
Identities = 44/137 (32%), Positives = 69/137 (50%), Gaps = 6/137 (4%)
Frame = +3
Query: 249 PTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGK-NPALVET 425
P L ++ VA G FHS ++++G Y G N GQ + + NP +
Sbjct: 82 PILENALVGQYVITVATGSFHSGAVTDNGVAYMWGENSAGQCAVANQQYVPEPNPVSIAD 141
Query: 426 FKDCTISTI-----ACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLA 590
+ + + ACG +H+LA+ + ++WG+ QLG A KP+ V+ LA
Sbjct: 142 SEASPLLAVRILQLACGEEHTLALSISREIWAWGTGC--QLGLITTAFPVTKPQKVEHLA 199
Query: 591 TKNVIQVACGAYHSVAL 641
+ V+QVACGA+HS+AL
Sbjct: 200 GRVVLQVACGAFHSLAL 216
Score = 64.9 bits (151), Expect = 4e-10
Identities = 53/188 (28%), Positives = 83/188 (44%), Gaps = 6/188 (3%)
Frame = +3
Query: 255 LSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKD 434
L W +QA A G H + L+ G +YS G + G + +P L
Sbjct: 35 LPGWGGKTVLQA-ALGVKHGVLLTEDGEVYSFGTLP-WRSGPVEICPS--SPILENALVG 90
Query: 435 CTISTIACGLQHSLAIDEWGQPFSWGSDSMGQLG-NNLGAHAQDKPKFV-----KGLATK 596
+ T+A G HS A+ + G + WG +S GQ N + P + L
Sbjct: 91 QYVITVATGSFHSGAVTDNGVAYMWGENSAGQCAVANQQYVPEPNPVSIADSEASPLLAV 150
Query: 597 NVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIAC 776
++Q+ACG H++AL+ S ++++WG Q GL T + PQ + L G + +AC
Sbjct: 151 RILQLACGEEHTLALSISREIWAWGTGC--QLGLITTAFPVTKPQKVEHLAGRVVLQVAC 208
Query: 777 GNNHTFVL 800
G H+ L
Sbjct: 209 GAFHSLAL 216
Score = 60.9 bits (141), Expect = 6e-09
Identities = 44/121 (36%), Positives = 58/121 (47%)
Frame = +3
Query: 438 TISTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVAC 617
T S A L SL + W +WG GQLG+ + +P VK L K VI +
Sbjct: 512 TYSGEADALLPSLRTEVW----TWGKGKEGQLGHG-DVLPRLQPLCVKCLDGKEVIHLEA 566
Query: 618 GAYHSVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFV 797
G YHS+ALT +YSWG+N++GQ G ISS GV IA G +++
Sbjct: 567 GGYHSLALTAKSQVYSWGSNTFGQLGHSDFPTTVPRLAKISSENGV--WSIAAGRDYSLF 624
Query: 798 L 800
L
Sbjct: 625 L 625
Score = 54.0 bits (124), Expect = 7e-07
Identities = 28/93 (30%), Positives = 49/93 (52%)
Frame = +3
Query: 567 PKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSL 746
P+ + G K V+Q A G H V LT G++YS+G + G + SP ++L
Sbjct: 32 PERLPGWGGKTVLQAALGVKHGVLLTEDGEVYSFGTLPWRS---GPVEICPSSPILENAL 88
Query: 747 IGVPIALIACGNNHTFVLSKSGAVFGWGKNTHG 845
+G + +A G+ H+ ++ +G + WG+N+ G
Sbjct: 89 VGQYVITVATGSFHSGAVTDNGVAYMWGENSAG 121
Score = 45.6 bits (103), Expect = 2e-04
Identities = 20/67 (29%), Positives = 33/67 (49%)
Frame = +3
Query: 654 DLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFVLSKSGAVFGWGK 833
++++WG GQ G G + + + P + L G + + G H+ L+ V+ WG
Sbjct: 527 EVWTWGKGKEGQLGHGDVLPR-LQPLCVKCLDGKEVIHLEAGGYHSLALTAKSQVYSWGS 585
Query: 834 NTHGXLG 854
NT G LG
Sbjct: 586 NTFGQLG 592
Score = 45.2 bits (102), Expect = 3e-04
Identities = 33/120 (27%), Positives = 54/120 (45%)
Frame = +3
Query: 297 AGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSL 476
+GE +L S +++ G GQLG P V+ + + G HSL
Sbjct: 514 SGEADALLPSLRTEVWTWGKGKEGQLGHGDVLPR-LQPLCVKCLDGKEVIHLEAGGYHSL 572
Query: 477 AIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGD 656
A+ Q +SWGS++ GQLG++ P+ K + V +A G +S+ L ++ D
Sbjct: 573 ALTAKSQVYSWGSNTFGQLGHS--DFPTTVPRLAKISSENGVWSIAAGRDYSLFLVDTED 630
Score = 37.1 bits (82), Expect = 0.081
Identities = 23/78 (29%), Positives = 37/78 (47%)
Frame = +3
Query: 243 IKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVE 422
++P K + + + AG +HSL L+ +YS G+N GQLG P L +
Sbjct: 548 LQPLCVKCLDGKEVIHLEAGGYHSLALTAKSQVYSWGSNTFGQLGHSDFPTT--VPRLAK 605
Query: 423 TFKDCTISTIACGLQHSL 476
+ + +IA G +SL
Sbjct: 606 ISSENGVWSIAAGRDYSL 623
>AB046783-1|BAB13389.2| 1658|Homo sapiens KIAA1563 protein protein.
Length = 1658
Score = 70.5 bits (165), Expect = 7e-12
Identities = 45/137 (32%), Positives = 67/137 (48%), Gaps = 6/137 (4%)
Frame = +3
Query: 438 TISTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVAC 617
T+ A G++H + + E G+ +S+G+ + P L + VI VA
Sbjct: 43 TVLQAALGVKHGVLLTEDGEVYSFGTLPWRSGPVEI---CPSSPILENALVGQYVITVAT 99
Query: 618 GAYHSVALTNSGDLYSWGANSYGQCGLGTISN-KEMSPQHI-----SSLIGVPIALIACG 779
G++HS A+T++G Y WG NS GQC + E +P I S L+ V I +ACG
Sbjct: 100 GSFHSGAVTDNGVAYMWGENSAGQCAVANQQYVPEPNPVSIADSEASPLLAVRILQLACG 159
Query: 780 NNHTFVLSKSGAVFGWG 830
HT LS S ++ WG
Sbjct: 160 EEHTLALSISREIWAWG 176
Score = 65.3 bits (152), Expect = 3e-10
Identities = 44/137 (32%), Positives = 69/137 (50%), Gaps = 6/137 (4%)
Frame = +3
Query: 249 PTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGK-NPALVET 425
P L ++ VA G FHS ++++G Y G N GQ + + NP +
Sbjct: 83 PILENALVGQYVITVATGSFHSGAVTDNGVAYMWGENSAGQCAVANQQYVPEPNPVSIAD 142
Query: 426 FKDCTISTI-----ACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLA 590
+ + + ACG +H+LA+ + ++WG+ QLG A KP+ V+ LA
Sbjct: 143 SEASPLLAVRILQLACGEEHTLALSISREIWAWGTGC--QLGLITTAFPVTKPQKVEHLA 200
Query: 591 TKNVIQVACGAYHSVAL 641
+ V+QVACGA+HS+AL
Sbjct: 201 GRVVLQVACGAFHSLAL 217
Score = 64.9 bits (151), Expect = 4e-10
Identities = 53/188 (28%), Positives = 83/188 (44%), Gaps = 6/188 (3%)
Frame = +3
Query: 255 LSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKD 434
L W +QA A G H + L+ G +YS G + G + +P L
Sbjct: 36 LPGWGGKTVLQA-ALGVKHGVLLTEDGEVYSFGTLP-WRSGPVEICPS--SPILENALVG 91
Query: 435 CTISTIACGLQHSLAIDEWGQPFSWGSDSMGQLG-NNLGAHAQDKPKFV-----KGLATK 596
+ T+A G HS A+ + G + WG +S GQ N + P + L
Sbjct: 92 QYVITVATGSFHSGAVTDNGVAYMWGENSAGQCAVANQQYVPEPNPVSIADSEASPLLAV 151
Query: 597 NVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIAC 776
++Q+ACG H++AL+ S ++++WG Q GL T + PQ + L G + +AC
Sbjct: 152 RILQLACGEEHTLALSISREIWAWGTGC--QLGLITTAFPVTKPQKVEHLAGRVVLQVAC 209
Query: 777 GNNHTFVL 800
G H+ L
Sbjct: 210 GAFHSLAL 217
Score = 60.9 bits (141), Expect = 6e-09
Identities = 44/121 (36%), Positives = 58/121 (47%)
Frame = +3
Query: 438 TISTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVAC 617
T S A L SL + W +WG GQLG+ + +P VK L K VI +
Sbjct: 513 TYSGEADALLPSLRTEVW----TWGKGKEGQLGHG-DVLPRLQPLCVKCLDGKEVIHLEA 567
Query: 618 GAYHSVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFV 797
G YHS+ALT +YSWG+N++GQ G ISS GV IA G +++
Sbjct: 568 GGYHSLALTAKSQVYSWGSNTFGQLGHSDFPTTVPRLAKISSENGV--WSIAAGRDYSLF 625
Query: 798 L 800
L
Sbjct: 626 L 626
Score = 54.0 bits (124), Expect = 7e-07
Identities = 28/93 (30%), Positives = 49/93 (52%)
Frame = +3
Query: 567 PKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSL 746
P+ + G K V+Q A G H V LT G++YS+G + G + SP ++L
Sbjct: 33 PERLPGWGGKTVLQAALGVKHGVLLTEDGEVYSFGTLPWRS---GPVEICPSSPILENAL 89
Query: 747 IGVPIALIACGNNHTFVLSKSGAVFGWGKNTHG 845
+G + +A G+ H+ ++ +G + WG+N+ G
Sbjct: 90 VGQYVITVATGSFHSGAVTDNGVAYMWGENSAG 122
Score = 45.6 bits (103), Expect = 2e-04
Identities = 20/67 (29%), Positives = 33/67 (49%)
Frame = +3
Query: 654 DLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFVLSKSGAVFGWGK 833
++++WG GQ G G + + + P + L G + + G H+ L+ V+ WG
Sbjct: 528 EVWTWGKGKEGQLGHGDVLPR-LQPLCVKCLDGKEVIHLEAGGYHSLALTAKSQVYSWGS 586
Query: 834 NTHGXLG 854
NT G LG
Sbjct: 587 NTFGQLG 593
Score = 45.2 bits (102), Expect = 3e-04
Identities = 33/120 (27%), Positives = 54/120 (45%)
Frame = +3
Query: 297 AGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSL 476
+GE +L S +++ G GQLG P V+ + + G HSL
Sbjct: 515 SGEADALLPSLRTEVWTWGKGKEGQLGHGDVLPR-LQPLCVKCLDGKEVIHLEAGGYHSL 573
Query: 477 AIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGD 656
A+ Q +SWGS++ GQLG++ P+ K + V +A G +S+ L ++ D
Sbjct: 574 ALTAKSQVYSWGSNTFGQLGHS--DFPTTVPRLAKISSENGVWSIAAGRDYSLFLVDTED 631
Score = 37.1 bits (82), Expect = 0.081
Identities = 23/78 (29%), Positives = 37/78 (47%)
Frame = +3
Query: 243 IKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVE 422
++P K + + + AG +HSL L+ +YS G+N GQLG P L +
Sbjct: 549 LQPLCVKCLDGKEVIHLEAGGYHSLALTAKSQVYSWGSNTFGQLGHSDFPTT--VPRLAK 606
Query: 423 TFKDCTISTIACGLQHSL 476
+ + +IA G +SL
Sbjct: 607 ISSENGVWSIAAGRDYSL 624
>BC029174-1|AAH29174.1| 812|Homo sapiens ALS2 protein protein.
Length = 812
Score = 69.7 bits (163), Expect = 1e-11
Identities = 45/137 (32%), Positives = 70/137 (51%), Gaps = 6/137 (4%)
Frame = +3
Query: 249 PTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGK-NPALVET 425
P L ++ VA G FHS ++++G Y CG N GQ + + NP +
Sbjct: 82 PILENALVGQYVITVATGSFHSGAVTDNGVAYMCGENSAGQCAVANQQYVPEPNPVSIAD 141
Query: 426 FKDCTISTI-----ACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLA 590
+ + + ACG +H+LA+ + ++WG+ QLG A KP+ V+ LA
Sbjct: 142 SEASPLLAVRILQLACGEEHTLALSISREIWAWGTGC--QLGLITTAFPVTKPQKVEHLA 199
Query: 591 TKNVIQVACGAYHSVAL 641
+ V+QVACGA+HS+AL
Sbjct: 200 GRVVLQVACGAFHSLAL 216
Score = 65.3 bits (152), Expect = 3e-10
Identities = 44/137 (32%), Positives = 66/137 (48%), Gaps = 6/137 (4%)
Frame = +3
Query: 438 TISTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVAC 617
T+ A G++H + + E G+ +S+G+ + P L + VI VA
Sbjct: 42 TVLQAALGVKHGVLLTEDGEVYSFGTLPWRSGPVEI---CPSSPILENALVGQYVITVAT 98
Query: 618 GAYHSVALTNSGDLYSWGANSYGQCGLGTISN-KEMSPQHI-----SSLIGVPIALIACG 779
G++HS A+T++G Y G NS GQC + E +P I S L+ V I +ACG
Sbjct: 99 GSFHSGAVTDNGVAYMCGENSAGQCAVANQQYVPEPNPVSIADSEASPLLAVRILQLACG 158
Query: 780 NNHTFVLSKSGAVFGWG 830
HT LS S ++ WG
Sbjct: 159 EEHTLALSISREIWAWG 175
Score = 60.9 bits (141), Expect = 6e-09
Identities = 44/121 (36%), Positives = 58/121 (47%)
Frame = +3
Query: 438 TISTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVAC 617
T S A L SL + W +WG GQLG+ + +P VK L K VI +
Sbjct: 512 TYSGEADALLPSLRTEVW----TWGKGKEGQLGHG-DVLPRLQPLCVKCLDGKEVIHLEA 566
Query: 618 GAYHSVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFV 797
G YHS+ALT +YSWG+N++GQ G ISS GV IA G +++
Sbjct: 567 GGYHSLALTAKSQVYSWGSNTFGQLGHSDFPTTVPRLAKISSENGV--WSIAAGRDYSLF 624
Query: 798 L 800
L
Sbjct: 625 L 625
Score = 59.7 bits (138), Expect = 1e-08
Identities = 52/188 (27%), Positives = 82/188 (43%), Gaps = 6/188 (3%)
Frame = +3
Query: 255 LSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKD 434
L W +QA A G H + L+ G +YS G + G + +P L
Sbjct: 35 LPGWGGKTVLQA-ALGVKHGVLLTEDGEVYSFGTLP-WRSGPVEICPS--SPILENALVG 90
Query: 435 CTISTIACGLQHSLAIDEWGQPFSWGSDSMGQLG-NNLGAHAQDKPKFVKG-----LATK 596
+ T+A G HS A+ + G + G +S GQ N + P + L
Sbjct: 91 QYVITVATGSFHSGAVTDNGVAYMCGENSAGQCAVANQQYVPEPNPVSIADSEASPLLAV 150
Query: 597 NVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIAC 776
++Q+ACG H++AL+ S ++++WG Q GL T + PQ + L G + +AC
Sbjct: 151 RILQLACGEEHTLALSISREIWAWGTGC--QLGLITTAFPVTKPQKVEHLAGRVVLQVAC 208
Query: 777 GNNHTFVL 800
G H+ L
Sbjct: 209 GAFHSLAL 216
Score = 48.8 bits (111), Expect = 2e-05
Identities = 27/93 (29%), Positives = 48/93 (51%)
Frame = +3
Query: 567 PKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSL 746
P+ + G K V+Q A G H V LT G++YS+G + G + SP ++L
Sbjct: 32 PERLPGWGGKTVLQAALGVKHGVLLTEDGEVYSFGTLPWRS---GPVEICPSSPILENAL 88
Query: 747 IGVPIALIACGNNHTFVLSKSGAVFGWGKNTHG 845
+G + +A G+ H+ ++ +G + G+N+ G
Sbjct: 89 VGQYVITVATGSFHSGAVTDNGVAYMCGENSAG 121
Score = 45.6 bits (103), Expect = 2e-04
Identities = 20/67 (29%), Positives = 33/67 (49%)
Frame = +3
Query: 654 DLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFVLSKSGAVFGWGK 833
++++WG GQ G G + + + P + L G + + G H+ L+ V+ WG
Sbjct: 527 EVWTWGKGKEGQLGHGDVLPR-LQPLCVKCLDGKEVIHLEAGGYHSLALTAKSQVYSWGS 585
Query: 834 NTHGXLG 854
NT G LG
Sbjct: 586 NTFGQLG 592
Score = 45.2 bits (102), Expect = 3e-04
Identities = 33/120 (27%), Positives = 54/120 (45%)
Frame = +3
Query: 297 AGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSL 476
+GE +L S +++ G GQLG P V+ + + G HSL
Sbjct: 514 SGEADALLPSLRTEVWTWGKGKEGQLGHGDVLPR-LQPLCVKCLDGKEVIHLEAGGYHSL 572
Query: 477 AIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGD 656
A+ Q +SWGS++ GQLG++ P+ K + V +A G +S+ L ++ D
Sbjct: 573 ALTAKSQVYSWGSNTFGQLGHS--DFPTTVPRLAKISSENGVWSIAAGRDYSLFLVDTED 630
Score = 37.1 bits (82), Expect = 0.081
Identities = 23/78 (29%), Positives = 37/78 (47%)
Frame = +3
Query: 243 IKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVE 422
++P K + + + AG +HSL L+ +YS G+N GQLG P L +
Sbjct: 548 LQPLCVKCLDGKEVIHLEAGGYHSLALTAKSQVYSWGSNTFGQLGHSDFPTT--VPRLAK 605
Query: 423 TFKDCTISTIACGLQHSL 476
+ + +IA G +SL
Sbjct: 606 ISSENGVWSIAAGRDYSL 623
>AL359257-2|CAI39759.1| 4640|Homo sapiens AC001226.5 protein.
Length = 4640
Score = 67.7 bits (158), Expect = 5e-11
Identities = 34/84 (40%), Positives = 49/84 (58%)
Frame = +3
Query: 603 IQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGN 782
+QV+CG +HSV L +GD+Y++G +GQ G G + N P + +L G P + G+
Sbjct: 905 VQVSCGFHHSVVLMENGDVYTFGYGQHGQLGHGDV-NSRGCPTLVQALPG-PSTQVTAGS 962
Query: 783 NHTFVLSKSGAVFGWGKNTHGXLG 854
NHT VL G VF +G + G LG
Sbjct: 963 NHTAVLLMDGQVFTFGSFSKGQLG 986
Score = 50.8 bits (116), Expect = 6e-06
Identities = 46/178 (25%), Positives = 79/178 (44%), Gaps = 7/178 (3%)
Frame = +3
Query: 285 QAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTI--AC 458
QA+A H L + + G+ G+ G + S P F DC + + +C
Sbjct: 854 QALARLRSHPAQLKHKRDKHKDGS---GERGEKDASKITTYPPGSVRF-DCELRAVQVSC 909
Query: 459 GLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVA 638
G HS+ + E G +++G GQLG+ +++ P V+ L + QV G+ H+
Sbjct: 910 GFHHSVVLMENGDVYTFGYGQHGQLGHG-DVNSRGCPTLVQALPGPST-QVTAGSNHTAV 967
Query: 639 LTNSGDLYSWGANSYGQCGLGTIS----NKEMSPQ-HISSLIGVPIALIACGNNHTFV 797
L G ++++G+ S GQ G + N + +P +I S G I + TF+
Sbjct: 968 LLMDGQVFTFGSFSKGQLGRPILDVPYWNAKPAPMPNIGSKYGRKATWIGASGDQTFL 1025
Score = 48.0 bits (109), Expect = 4e-05
Identities = 35/136 (25%), Positives = 61/136 (44%), Gaps = 4/136 (2%)
Frame = +3
Query: 309 HSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNP----ALVETFKDCTISTIACGLQHSL 476
H+L ++ G ++ G+ G+ G T+S P +++ + T AC S
Sbjct: 555 HALLVAEDGSIFFTGSASKGEDGESTKSRRQSKPYKPKKIIKMEGKIVVYT-ACNNGSSS 613
Query: 477 AIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGD 656
I + G+ + +G D++ D V L V QVA G H+ L +G+
Sbjct: 614 VISKDGELYMFGKDAI----------YSDSSSLVTDLKGHFVTQVAMGKAHTCVLMKNGE 663
Query: 657 LYSWGANSYGQCGLGT 704
++++G N+ GQCG T
Sbjct: 664 VWTFGVNNKGQCGRDT 679
Score = 39.5 bits (88), Expect = 0.015
Identities = 21/73 (28%), Positives = 38/73 (52%), Gaps = 3/73 (4%)
Frame = +3
Query: 627 HSVALTNSGDLYSWGANSYGQCGLGTIS---NKEMSPQHISSLIGVPIALIACGNNHTFV 797
H++ + G ++ G+ S G+ G T S +K P+ I + G + AC N + V
Sbjct: 555 HALLVAEDGSIFFTGSASKGEDGESTKSRRQSKPYKPKKIIKMEGKIVVYTACNNGSSSV 614
Query: 798 LSKSGAVFGWGKN 836
+SK G ++ +GK+
Sbjct: 615 ISKDGELYMFGKD 627
>AL159158-1|CAI16842.1| 4640|Homo sapiens AC001226.5 protein.
Length = 4640
Score = 67.7 bits (158), Expect = 5e-11
Identities = 34/84 (40%), Positives = 49/84 (58%)
Frame = +3
Query: 603 IQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGN 782
+QV+CG +HSV L +GD+Y++G +GQ G G + N P + +L G P + G+
Sbjct: 905 VQVSCGFHHSVVLMENGDVYTFGYGQHGQLGHGDV-NSRGCPTLVQALPG-PSTQVTAGS 962
Query: 783 NHTFVLSKSGAVFGWGKNTHGXLG 854
NHT VL G VF +G + G LG
Sbjct: 963 NHTAVLLMDGQVFTFGSFSKGQLG 986
Score = 50.8 bits (116), Expect = 6e-06
Identities = 46/178 (25%), Positives = 79/178 (44%), Gaps = 7/178 (3%)
Frame = +3
Query: 285 QAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTI--AC 458
QA+A H L + + G+ G+ G + S P F DC + + +C
Sbjct: 854 QALARLRSHPAQLKHKRDKHKDGS---GERGEKDASKITTYPPGSVRF-DCELRAVQVSC 909
Query: 459 GLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVA 638
G HS+ + E G +++G GQLG+ +++ P V+ L + QV G+ H+
Sbjct: 910 GFHHSVVLMENGDVYTFGYGQHGQLGHG-DVNSRGCPTLVQALPGPST-QVTAGSNHTAV 967
Query: 639 LTNSGDLYSWGANSYGQCGLGTIS----NKEMSPQ-HISSLIGVPIALIACGNNHTFV 797
L G ++++G+ S GQ G + N + +P +I S G I + TF+
Sbjct: 968 LLMDGQVFTFGSFSKGQLGRPILDVPYWNAKPAPMPNIGSKYGRKATWIGASGDQTFL 1025
Score = 48.0 bits (109), Expect = 4e-05
Identities = 35/136 (25%), Positives = 61/136 (44%), Gaps = 4/136 (2%)
Frame = +3
Query: 309 HSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNP----ALVETFKDCTISTIACGLQHSL 476
H+L ++ G ++ G+ G+ G T+S P +++ + T AC S
Sbjct: 555 HALLVAEDGSIFFTGSASKGEDGESTKSRRQSKPYKPKKIIKMEGKIVVYT-ACNNGSSS 613
Query: 477 AIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGD 656
I + G+ + +G D++ D V L V QVA G H+ L +G+
Sbjct: 614 VISKDGELYMFGKDAI----------YSDSSSLVTDLKGHFVTQVAMGKAHTCVLMKNGE 663
Query: 657 LYSWGANSYGQCGLGT 704
++++G N+ GQCG T
Sbjct: 664 VWTFGVNNKGQCGRDT 679
Score = 39.5 bits (88), Expect = 0.015
Identities = 21/73 (28%), Positives = 38/73 (52%), Gaps = 3/73 (4%)
Frame = +3
Query: 627 HSVALTNSGDLYSWGANSYGQCGLGTIS---NKEMSPQHISSLIGVPIALIACGNNHTFV 797
H++ + G ++ G+ S G+ G T S +K P+ I + G + AC N + V
Sbjct: 555 HALLVAEDGSIFFTGSASKGEDGESTKSRRQSKPYKPKKIIKMEGKIVVYTACNNGSSSV 614
Query: 798 LSKSGAVFGWGKN 836
+SK G ++ +GK+
Sbjct: 615 ISKDGELYMFGKD 627
>AL159154-1|CAH73736.1| 4640|Homo sapiens AC001226.5 protein.
Length = 4640
Score = 67.7 bits (158), Expect = 5e-11
Identities = 34/84 (40%), Positives = 49/84 (58%)
Frame = +3
Query: 603 IQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGN 782
+QV+CG +HSV L +GD+Y++G +GQ G G + N P + +L G P + G+
Sbjct: 905 VQVSCGFHHSVVLMENGDVYTFGYGQHGQLGHGDV-NSRGCPTLVQALPG-PSTQVTAGS 962
Query: 783 NHTFVLSKSGAVFGWGKNTHGXLG 854
NHT VL G VF +G + G LG
Sbjct: 963 NHTAVLLMDGQVFTFGSFSKGQLG 986
Score = 50.8 bits (116), Expect = 6e-06
Identities = 46/178 (25%), Positives = 79/178 (44%), Gaps = 7/178 (3%)
Frame = +3
Query: 285 QAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTI--AC 458
QA+A H L + + G+ G+ G + S P F DC + + +C
Sbjct: 854 QALARLRSHPAQLKHKRDKHKDGS---GERGEKDASKITTYPPGSVRF-DCELRAVQVSC 909
Query: 459 GLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVA 638
G HS+ + E G +++G GQLG+ +++ P V+ L + QV G+ H+
Sbjct: 910 GFHHSVVLMENGDVYTFGYGQHGQLGHG-DVNSRGCPTLVQALPGPST-QVTAGSNHTAV 967
Query: 639 LTNSGDLYSWGANSYGQCGLGTIS----NKEMSPQ-HISSLIGVPIALIACGNNHTFV 797
L G ++++G+ S GQ G + N + +P +I S G I + TF+
Sbjct: 968 LLMDGQVFTFGSFSKGQLGRPILDVPYWNAKPAPMPNIGSKYGRKATWIGASGDQTFL 1025
Score = 48.0 bits (109), Expect = 4e-05
Identities = 35/136 (25%), Positives = 61/136 (44%), Gaps = 4/136 (2%)
Frame = +3
Query: 309 HSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNP----ALVETFKDCTISTIACGLQHSL 476
H+L ++ G ++ G+ G+ G T+S P +++ + T AC S
Sbjct: 555 HALLVAEDGSIFFTGSASKGEDGESTKSRRQSKPYKPKKIIKMEGKIVVYT-ACNNGSSS 613
Query: 477 AIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGD 656
I + G+ + +G D++ D V L V QVA G H+ L +G+
Sbjct: 614 VISKDGELYMFGKDAI----------YSDSSSLVTDLKGHFVTQVAMGKAHTCVLMKNGE 663
Query: 657 LYSWGANSYGQCGLGT 704
++++G N+ GQCG T
Sbjct: 664 VWTFGVNNKGQCGRDT 679
Score = 39.5 bits (88), Expect = 0.015
Identities = 21/73 (28%), Positives = 38/73 (52%), Gaps = 3/73 (4%)
Frame = +3
Query: 627 HSVALTNSGDLYSWGANSYGQCGLGTIS---NKEMSPQHISSLIGVPIALIACGNNHTFV 797
H++ + G ++ G+ S G+ G T S +K P+ I + G + AC N + V
Sbjct: 555 HALLVAEDGSIFFTGSASKGEDGESTKSRRQSKPYKPKKIIKMEGKIVVYTACNNGSSSV 614
Query: 798 LSKSGAVFGWGKN 836
+SK G ++ +GK+
Sbjct: 615 ISKDGELYMFGKD 627
>AF075587-1|AAC39928.1| 4641|Homo sapiens protein associated with Myc
protein.
Length = 4641
Score = 67.7 bits (158), Expect = 5e-11
Identities = 34/84 (40%), Positives = 49/84 (58%)
Frame = +3
Query: 603 IQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGN 782
+QV+CG +HSV L +GD+Y++G +GQ G G + N P + +L G P + G+
Sbjct: 905 VQVSCGFHHSVVLMENGDVYTFGYGQHGQLGHGDV-NSRGCPTLVQALPG-PSTQVTAGS 962
Query: 783 NHTFVLSKSGAVFGWGKNTHGXLG 854
NHT VL G VF +G + G LG
Sbjct: 963 NHTAVLLMDGQVFTFGSFSKGQLG 986
Score = 50.8 bits (116), Expect = 6e-06
Identities = 45/178 (25%), Positives = 80/178 (44%), Gaps = 7/178 (3%)
Frame = +3
Query: 285 QAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTI--AC 458
QA+A H ++ + + G+ G+ G + S P F DC + + +C
Sbjct: 854 QALARLRSHPAHVKHKRDKHKDGS---GERGEKDASKITTYPPGSVRF-DCELRAVQVSC 909
Query: 459 GLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVA 638
G HS+ + E G +++G GQLG+ +++ P V+ L + QV G+ H+
Sbjct: 910 GFHHSVVLMENGDVYTFGYGQHGQLGHG-DVNSRGCPTLVQALPGPST-QVTAGSNHTAV 967
Query: 639 LTNSGDLYSWGANSYGQCGLGTIS----NKEMSPQ-HISSLIGVPIALIACGNNHTFV 797
L G ++++G+ S GQ G + N + +P +I S G I + TF+
Sbjct: 968 LLMDGQVFTFGSFSKGQLGRPILDVPYWNAKPAPMPNIGSKYGRKATWIGASGDQTFL 1025
Score = 45.6 bits (103), Expect = 2e-04
Identities = 34/136 (25%), Positives = 60/136 (44%), Gaps = 4/136 (2%)
Frame = +3
Query: 309 HSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNP----ALVETFKDCTISTIACGLQHSL 476
H+L ++ G ++ G+ G+ G +S P +++ + T AC S
Sbjct: 555 HALLVAEDGSIFFTGSASKGEDGESIKSRRQSKPYKPKKIIKMEGKIVVYT-ACNNGSSS 613
Query: 477 AIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGD 656
I + G+ + +G D++ D V L V QVA G H+ L +G+
Sbjct: 614 VISKDGELYMFGKDAI----------YSDSSSLVTDLKGHFVTQVAMGKAHTCVLMKNGE 663
Query: 657 LYSWGANSYGQCGLGT 704
++++G N+ GQCG T
Sbjct: 664 VWTFGVNNKGQCGRDT 679
Score = 37.1 bits (82), Expect = 0.081
Identities = 20/73 (27%), Positives = 37/73 (50%), Gaps = 3/73 (4%)
Frame = +3
Query: 627 HSVALTNSGDLYSWGANSYGQCGLGTIS---NKEMSPQHISSLIGVPIALIACGNNHTFV 797
H++ + G ++ G+ S G+ G S +K P+ I + G + AC N + V
Sbjct: 555 HALLVAEDGSIFFTGSASKGEDGESIKSRRQSKPYKPKKIIKMEGKIVVYTACNNGSSSV 614
Query: 798 LSKSGAVFGWGKN 836
+SK G ++ +GK+
Sbjct: 615 ISKDGELYMFGKD 627
>AC007279-1|AAY15058.1| 1598|Homo sapiens unknown protein.
Length = 1598
Score = 65.3 bits (152), Expect = 3e-10
Identities = 44/137 (32%), Positives = 69/137 (50%), Gaps = 6/137 (4%)
Frame = +3
Query: 249 PTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGK-NPALVET 425
P L ++ VA G FHS ++++G Y G N GQ + + NP +
Sbjct: 23 PILENALVGQYVITVATGSFHSGAVTDNGVAYMWGENSAGQCAVANQQYVPEPNPVSIAD 82
Query: 426 FKDCTISTI-----ACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLA 590
+ + + ACG +H+LA+ + ++WG+ QLG A KP+ V+ LA
Sbjct: 83 SEASPLLAVRILQLACGEEHTLALSISREIWAWGTGC--QLGLITTAFPVTKPQKVEHLA 140
Query: 591 TKNVIQVACGAYHSVAL 641
+ V+QVACGA+HS+AL
Sbjct: 141 GRVVLQVACGAFHSLAL 157
Score = 64.5 bits (150), Expect = 5e-10
Identities = 37/94 (39%), Positives = 49/94 (52%), Gaps = 6/94 (6%)
Frame = +3
Query: 567 PKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTISN-KEMSPQHI-- 737
P L + VI VA G++HS A+T++G Y WG NS GQC + E +P I
Sbjct: 23 PILENALVGQYVITVATGSFHSGAVTDNGVAYMWGENSAGQCAVANQQYVPEPNPVSIAD 82
Query: 738 ---SSLIGVPIALIACGNNHTFVLSKSGAVFGWG 830
S L+ V I +ACG HT LS S ++ WG
Sbjct: 83 SEASPLLAVRILQLACGEEHTLALSISREIWAWG 116
Score = 61.3 bits (142), Expect = 4e-09
Identities = 40/138 (28%), Positives = 64/138 (46%), Gaps = 6/138 (4%)
Frame = +3
Query: 405 NPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQLG-NNLGAHAQDKPKFV- 578
+P L + T+A G HS A+ + G + WG +S GQ N + P +
Sbjct: 22 SPILENALVGQYVITVATGSFHSGAVTDNGVAYMWGENSAGQCAVANQQYVPEPNPVSIA 81
Query: 579 ----KGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSL 746
L ++Q+ACG H++AL+ S ++++WG Q GL T + PQ + L
Sbjct: 82 DSEASPLLAVRILQLACGEEHTLALSISREIWAWGTGC--QLGLITTAFPVTKPQKVEHL 139
Query: 747 IGVPIALIACGNNHTFVL 800
G + +ACG H+ L
Sbjct: 140 AGRVVLQVACGAFHSLAL 157
Score = 60.9 bits (141), Expect = 6e-09
Identities = 44/121 (36%), Positives = 58/121 (47%)
Frame = +3
Query: 438 TISTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVAC 617
T S A L SL + W +WG GQLG+ + +P VK L K VI +
Sbjct: 453 TYSGEADALLPSLRTEVW----TWGKGKEGQLGHG-DVLPRLQPLCVKCLDGKEVIHLEA 507
Query: 618 GAYHSVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFV 797
G YHS+ALT +YSWG+N++GQ G ISS GV IA G +++
Sbjct: 508 GGYHSLALTAKSQVYSWGSNTFGQLGHSDFPTTVPRLAKISSENGV--WSIAAGRDYSLF 565
Query: 798 L 800
L
Sbjct: 566 L 566
Score = 45.6 bits (103), Expect = 2e-04
Identities = 20/67 (29%), Positives = 33/67 (49%)
Frame = +3
Query: 654 DLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFVLSKSGAVFGWGK 833
++++WG GQ G G + + + P + L G + + G H+ L+ V+ WG
Sbjct: 468 EVWTWGKGKEGQLGHGDVLPR-LQPLCVKCLDGKEVIHLEAGGYHSLALTAKSQVYSWGS 526
Query: 834 NTHGXLG 854
NT G LG
Sbjct: 527 NTFGQLG 533
Score = 45.2 bits (102), Expect = 3e-04
Identities = 33/120 (27%), Positives = 54/120 (45%)
Frame = +3
Query: 297 AGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSL 476
+GE +L S +++ G GQLG P V+ + + G HSL
Sbjct: 455 SGEADALLPSLRTEVWTWGKGKEGQLGHGDVLPR-LQPLCVKCLDGKEVIHLEAGGYHSL 513
Query: 477 AIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGD 656
A+ Q +SWGS++ GQLG++ P+ K + V +A G +S+ L ++ D
Sbjct: 514 ALTAKSQVYSWGSNTFGQLGHS--DFPTTVPRLAKISSENGVWSIAAGRDYSLFLVDTED 571
Score = 37.1 bits (82), Expect = 0.081
Identities = 23/78 (29%), Positives = 37/78 (47%)
Frame = +3
Query: 243 IKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVE 422
++P K + + + AG +HSL L+ +YS G+N GQLG P L +
Sbjct: 489 LQPLCVKCLDGKEVIHLEAGGYHSLALTAKSQVYSWGSNTFGQLGHSDFPTT--VPRLAK 546
Query: 423 TFKDCTISTIACGLQHSL 476
+ + +IA G +SL
Sbjct: 547 ISSENGVWSIAAGRDYSL 564
Score = 33.9 bits (74), Expect = 0.76
Identities = 17/65 (26%), Positives = 35/65 (53%)
Frame = +3
Query: 651 GDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACGNNHTFVLSKSGAVFGWG 830
G++YS+G + G + SP ++L+G + +A G+ H+ ++ +G + WG
Sbjct: 1 GEVYSFGTLPWRS---GPVEICPSSPILENALVGQYVITVATGSFHSGAVTDNGVAYMWG 57
Query: 831 KNTHG 845
+N+ G
Sbjct: 58 ENSAG 62
>AY650032-1|AAV66578.1| 117|Homo sapiens HECT and RCC1 containing
protein 4 isoform 2 protein.
Length = 117
Score = 56.8 bits (131), Expect = 9e-08
Identities = 31/93 (33%), Positives = 53/93 (56%)
Frame = +3
Query: 174 MFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCG 353
M CWGNA+ +L + G ++V++P S + + ++ V G H++++ + G +Y+CG
Sbjct: 1 MLCWGNASFGQLGLGGID-EEIVLEPRKSDFFINKRVRDVGCGLRHTVFVLDDGTVYTCG 59
Query: 354 NNDVGQLGRQTESDNGKNPALVETFKDCTISTI 452
ND+GQLG + + K P E K C IS +
Sbjct: 60 CNDLGQLGHE---KSRKKP---EILKVCQISRL 86
Score = 42.7 bits (96), Expect = 0.002
Identities = 22/64 (34%), Positives = 31/64 (48%), Gaps = 1/64 (1%)
Frame = +3
Query: 507 WGSDSMGQLG-NNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSY 683
WG+ S GQLG + +P+ K V V CG H+V + + G +Y+ G N
Sbjct: 4 WGNASFGQLGLGGIDEEIVLEPRKSDFFINKRVRDVGCGLRHTVFVLDDGTVYTCGCNDL 63
Query: 684 GQCG 695
GQ G
Sbjct: 64 GQLG 67
Score = 41.1 bits (92), Expect = 0.005
Identities = 22/64 (34%), Positives = 30/64 (46%), Gaps = 1/64 (1%)
Frame = +3
Query: 666 WGANSYGQCGLGTISNK-EMSPQHISSLIGVPIALIACGNNHTFVLSKSGAVFGWGKNTH 842
WG S+GQ GLG I + + P+ I + + CG HT + G V+ G N
Sbjct: 4 WGNASFGQLGLGGIDEEIVLEPRKSDFFINKRVRDVGCGLRHTVFVLDDGTVYTCGCNDL 63
Query: 843 GXLG 854
G LG
Sbjct: 64 GQLG 67
Score = 36.3 bits (80), Expect = 0.14
Identities = 21/78 (26%), Positives = 41/78 (52%), Gaps = 1/78 (1%)
Frame = +3
Query: 351 GNNDVGQLGRQ-TESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMG 527
GN GQLG + + P + F + + + CGL+H++ + + G ++ G + +G
Sbjct: 5 GNASFGQLGLGGIDEEIVLEPRKSDFFINKRVRDVGCGLRHTVFVLDDGTVYTCGCNDLG 64
Query: 528 QLGNNLGAHAQDKPKFVK 581
QLG+ ++ KP+ +K
Sbjct: 65 QLGHE---KSRKKPEILK 79
>AY650034-1|AAV66580.1| 110|Homo sapiens HECT and RCC1 containing
protein 4 isoform 4 protein.
Length = 110
Score = 55.6 bits (128), Expect = 2e-07
Identities = 24/70 (34%), Positives = 44/70 (62%)
Frame = +3
Query: 174 MFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCG 353
M CWGNA+ +L + G ++V++P S + + ++ V G H++++ + G +Y+CG
Sbjct: 1 MLCWGNASFGQLGLGGID-EEIVLEPRKSDFFINKRVRDVGCGLRHTVFVLDDGTVYTCG 59
Query: 354 NNDVGQLGRQ 383
ND+GQLG +
Sbjct: 60 CNDLGQLGHE 69
Score = 42.7 bits (96), Expect = 0.002
Identities = 22/64 (34%), Positives = 31/64 (48%), Gaps = 1/64 (1%)
Frame = +3
Query: 507 WGSDSMGQLG-NNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSY 683
WG+ S GQLG + +P+ K V V CG H+V + + G +Y+ G N
Sbjct: 4 WGNASFGQLGLGGIDEEIVLEPRKSDFFINKRVRDVGCGLRHTVFVLDDGTVYTCGCNDL 63
Query: 684 GQCG 695
GQ G
Sbjct: 64 GQLG 67
Score = 41.1 bits (92), Expect = 0.005
Identities = 22/64 (34%), Positives = 30/64 (46%), Gaps = 1/64 (1%)
Frame = +3
Query: 666 WGANSYGQCGLGTISNK-EMSPQHISSLIGVPIALIACGNNHTFVLSKSGAVFGWGKNTH 842
WG S+GQ GLG I + + P+ I + + CG HT + G V+ G N
Sbjct: 4 WGNASFGQLGLGGIDEEIVLEPRKSDFFINKRVRDVGCGLRHTVFVLDDGTVYTCGCNDL 63
Query: 843 GXLG 854
G LG
Sbjct: 64 GQLG 67
Score = 36.3 bits (80), Expect = 0.14
Identities = 21/76 (27%), Positives = 40/76 (52%), Gaps = 1/76 (1%)
Frame = +3
Query: 351 GNNDVGQLGRQ-TESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMG 527
GN GQLG + + P + F + + + CGL+H++ + + G ++ G + +G
Sbjct: 5 GNASFGQLGLGGIDEEIVLEPRKSDFFINKRVRDVGCGLRHTVFVLDDGTVYTCGCNDLG 64
Query: 528 QLGNNLGAHAQDKPKF 575
QLG+ ++ KP+F
Sbjct: 65 QLGHE---KSRKKPEF 77
>AF225404-1|AAO27482.1| 259|Homo sapiens HERC2 protein.
Length = 259
Score = 50.8 bits (116), Expect = 6e-06
Identities = 39/135 (28%), Positives = 61/135 (45%), Gaps = 2/135 (1%)
Frame = +3
Query: 312 SLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEW 491
+L SG +Y G+N GQLG E K P E + G Q A+
Sbjct: 120 TLSAGGSGTIYGWGHNHRGQLGG-IEGAKVKVPTPCEALATLRPVQLIGGEQTLFAVTAD 178
Query: 492 GQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVAC--GAYHSVALTNSGDLYS 665
G+ ++ G + G+LG G + P ++ + + +VA G H +AL++ G++YS
Sbjct: 179 GKLYATGYGAGGRLGIG-GTESVSTPTLLESIQHVFIKKVAVNSGGKHCLALSSEGEVYS 237
Query: 666 WGANSYGQCGLGTIS 710
WG G+ G G S
Sbjct: 238 WGEAEDGKLGHGNRS 252
>BC113826-1|AAI13827.1| 244|Homo sapiens RCCD1 protein protein.
Length = 244
Score = 50.4 bits (115), Expect = 8e-06
Identities = 45/187 (24%), Positives = 85/187 (45%), Gaps = 2/187 (1%)
Frame = +3
Query: 243 IKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVE 422
++P L + + + VAAG +HS+ +S +G +Y G N+ GQL T + L E
Sbjct: 67 LEPRLLEALQGLVMAEVAAGGWHSVCVSETGDIYIWGWNESGQLALPTRN-------LAE 119
Query: 423 TFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNV 602
+ T++ A L ++ Q G G + Q P + +
Sbjct: 120 DGE--TVAREATELN-----EDGSQVKRTGGAEDGAPAPFIAV--QPFPALLDLPMGSDA 170
Query: 603 IQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIG--VPIALIAC 776
++ +CG+ H+ +T +G+LY+WG YGQ G ++ + P+ + + + + + C
Sbjct: 171 VKASCGSRHTAVVTRTGELYTWGWGKYGQLGHEDTTSLD-RPRRVEYFVDKQLQVKAVTC 229
Query: 777 GNNHTFV 797
G +T+V
Sbjct: 230 GPWNTYV 236
Score = 49.6 bits (113), Expect = 1e-05
Identities = 24/63 (38%), Positives = 37/63 (58%)
Frame = +3
Query: 516 DSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSWGANSYGQCG 695
D GQLG+ A+ +P+ ++ L + +VA G +HSV ++ +GD+Y WG N GQ
Sbjct: 53 DPHGQLGHGT-LEAELEPRLLEALQGLVMAEVAAGGWHSVCVSETGDIYIWGWNESGQLA 111
Query: 696 LGT 704
L T
Sbjct: 112 LPT 114
Score = 44.0 bits (99), Expect = 7e-04
Identities = 39/164 (23%), Positives = 67/164 (40%), Gaps = 1/164 (0%)
Frame = +3
Query: 366 GQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNL 545
GQLG T + P L+E + ++ +A G HS+ + E G + WG + GQL
Sbjct: 56 GQLGHGT-LEAELEPRLLEALQGLVMAEVAAGGWHSVCVSETGDIYIWGWNESGQL---- 110
Query: 546 GAHAQDKPKFVKGLATKNVIQVA-CGAYHSVALTNSGDLYSWGANSYGQCGLGTISNKEM 722
L T+N+ + A + L G + I+ +
Sbjct: 111 ------------ALPTRNLAEDGETVAREATELNEDGSQVKRTGGAEDGAPAPFIAVQPF 158
Query: 723 SPQHISSLIGVPIALIACGNNHTFVLSKSGAVFGWGKNTHGXLG 854
P + +G +CG+ HT V++++G ++ WG +G LG
Sbjct: 159 -PALLDLPMGSDAVKASCGSRHTAVVTRTGELYTWGWGKYGQLG 201
>BC067293-1|AAH67293.1| 580|Homo sapiens F-box protein 24 protein.
Length = 580
Score = 34.7 bits (76), Expect = 0.43
Identities = 26/108 (24%), Positives = 46/108 (42%)
Frame = +3
Query: 453 ACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHS 632
A G H +DE+G+ F G++ GQLG D+ + + + I + CG HS
Sbjct: 363 ALGYNHLGLVDEFGRIFMQGNNRYGQLGT---GDKMDRGEPTQVCYLQRPITLWCGLNHS 419
Query: 633 VALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIAC 776
+ L+ S + + CG G P+ +S + + + + C
Sbjct: 420 LVLSQSSEF----SKELLGCGCGAGGRLPGWPKGSASFVKLQVKVPLC 463
Score = 34.3 bits (75), Expect = 0.57
Identities = 23/65 (35%), Positives = 32/65 (49%)
Frame = +3
Query: 294 AAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHS 473
A G H + G ++ GNN GQLG + D G+ P V + I T+ CGL HS
Sbjct: 363 ALGYNHLGLVDEFGRIFMQGNNRYGQLGTGDKMDRGE-PTQV-CYLQRPI-TLWCGLNHS 419
Query: 474 LAIDE 488
L + +
Sbjct: 420 LVLSQ 424
Score = 33.5 bits (73), Expect = 1.0
Identities = 24/70 (34%), Positives = 34/70 (48%)
Frame = +3
Query: 600 VIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACG 779
++ A G H + G ++ G N YGQ G G ++ P + L PI L CG
Sbjct: 359 ILFCALGYNHLGLVDEFGRIFMQGNNRYGQLGTGDKMDRG-EPTQVCYLQR-PITLW-CG 415
Query: 780 NNHTFVLSKS 809
NH+ VLS+S
Sbjct: 416 LNHSLVLSQS 425
Score = 30.3 bits (65), Expect = 9.3
Identities = 15/54 (27%), Positives = 27/54 (50%), Gaps = 2/54 (3%)
Frame = +3
Query: 699 GTISNKEMSPQHISSLIGVPIALIAC--GNNHTFVLSKSGAVFGWGKNTHGXLG 854
GT+ + Q + + +P ++ C G NH ++ + G +F G N +G LG
Sbjct: 337 GTLQAFDPLDQQMPLALSLPAKILFCALGYNHLGLVDEFGRIFMQGNNRYGQLG 390
>AC069281-1|AAP21863.1| 580|Homo sapiens unknown protein.
Length = 580
Score = 34.7 bits (76), Expect = 0.43
Identities = 26/108 (24%), Positives = 46/108 (42%)
Frame = +3
Query: 453 ACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHS 632
A G H +DE+G+ F G++ GQLG D+ + + + I + CG HS
Sbjct: 363 ALGYNHLGLVDEFGRIFMQGNNRYGQLGT---GDKMDRGEPTQVCYLQRPITLWCGLNHS 419
Query: 633 VALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIAC 776
+ L+ S + + CG G P+ +S + + + + C
Sbjct: 420 LVLSQSSEF----SKELLGCGCGAGGRLPGWPKGSASFVKLQVKVPLC 463
Score = 34.3 bits (75), Expect = 0.57
Identities = 23/65 (35%), Positives = 32/65 (49%)
Frame = +3
Query: 294 AAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHS 473
A G H + G ++ GNN GQLG + D G+ P V + I T+ CGL HS
Sbjct: 363 ALGYNHLGLVDEFGRIFMQGNNRYGQLGTGDKMDRGE-PTQV-CYLQRPI-TLWCGLNHS 419
Query: 474 LAIDE 488
L + +
Sbjct: 420 LVLSQ 424
Score = 33.5 bits (73), Expect = 1.0
Identities = 24/70 (34%), Positives = 34/70 (48%)
Frame = +3
Query: 600 VIQVACGAYHSVALTNSGDLYSWGANSYGQCGLGTISNKEMSPQHISSLIGVPIALIACG 779
++ A G H + G ++ G N YGQ G G ++ P + L PI L CG
Sbjct: 359 ILFCALGYNHLGLVDEFGRIFMQGNNRYGQLGTGDKMDRG-EPTQVCYLQR-PITLW-CG 415
Query: 780 NNHTFVLSKS 809
NH+ VLS+S
Sbjct: 416 LNHSLVLSQS 425
Score = 30.3 bits (65), Expect = 9.3
Identities = 15/54 (27%), Positives = 27/54 (50%), Gaps = 2/54 (3%)
Frame = +3
Query: 699 GTISNKEMSPQHISSLIGVPIALIAC--GNNHTFVLSKSGAVFGWGKNTHGXLG 854
GT+ + Q + + +P ++ C G NH ++ + G +F G N +G LG
Sbjct: 337 GTLQAFDPLDQQMPLALSLPAKILFCALGYNHLGLVDEFGRIFMQGNNRYGQLG 390
>BC151230-1|AAI51231.1| 1411|Homo sapiens KIAA0329 protein.
Length = 1411
Score = 31.9 bits (69), Expect = 3.1
Identities = 17/57 (29%), Positives = 26/57 (45%), Gaps = 5/57 (8%)
Frame = +3
Query: 666 WGANSYGQCGLGTISNKEMSPQH-----ISSLIGVPIALIACGNNHTFVLSKSGAVF 821
W +S GQ + T+S + H +S L V + +ACGN H + G V+
Sbjct: 1182 WALDSLGQVFIRTLSKSCPTGMHWTRLDLSQLGAVKLTSLACGNQHIWACDSRGGVY 1238
>BC142715-1|AAI42716.1| 1267|Homo sapiens KIAA0329 protein protein.
Length = 1267
Score = 31.9 bits (69), Expect = 3.1
Identities = 17/57 (29%), Positives = 26/57 (45%), Gaps = 5/57 (8%)
Frame = +3
Query: 666 WGANSYGQCGLGTISNKEMSPQH-----ISSLIGVPIALIACGNNHTFVLSKSGAVF 821
W +S GQ + T+S + H +S L V + +ACGN H + G V+
Sbjct: 1182 WALDSLGQVFIRTLSKSCPTGMHWTRLDLSQLGAVKLTSLACGNQHIWACDSRGGVY 1238
>BC142667-1|AAI42668.1| 1267|Homo sapiens KIAA0329 protein protein.
Length = 1267
Score = 31.9 bits (69), Expect = 3.1
Identities = 17/57 (29%), Positives = 26/57 (45%), Gaps = 5/57 (8%)
Frame = +3
Query: 666 WGANSYGQCGLGTISNKEMSPQH-----ISSLIGVPIALIACGNNHTFVLSKSGAVF 821
W +S GQ + T+S + H +S L V + +ACGN H + G V+
Sbjct: 1182 WALDSLGQVFIRTLSKSCPTGMHWTRLDLSQLGAVKLTSLACGNQHIWACDSRGGVY 1238
>AB002327-1|BAA20787.2| 1417|Homo sapiens KIAA0329 protein.
Length = 1417
Score = 31.9 bits (69), Expect = 3.1
Identities = 17/57 (29%), Positives = 26/57 (45%), Gaps = 5/57 (8%)
Frame = +3
Query: 666 WGANSYGQCGLGTISNKEMSPQH-----ISSLIGVPIALIACGNNHTFVLSKSGAVF 821
W +S GQ + T+S + H +S L V + +ACGN H + G V+
Sbjct: 1188 WALDSLGQVFIRTLSKSCPTGMHWTRLDLSQLGAVKLTSLACGNQHIWACDSRGGVY 1244
>AB002295-1|BAA20757.1| 1271|Homo sapiens KIAA0297 protein.
Length = 1271
Score = 31.9 bits (69), Expect = 3.1
Identities = 17/57 (29%), Positives = 26/57 (45%), Gaps = 5/57 (8%)
Frame = +3
Query: 666 WGANSYGQCGLGTISNKEMSPQH-----ISSLIGVPIALIACGNNHTFVLSKSGAVF 821
W +S GQ + T+S + H +S L V + +ACGN H + G V+
Sbjct: 1042 WALDSLGQVFIRTLSKSCPTGMHWTRLDLSQLGAVKLTSLACGNQHIWACDSRGGVY 1098
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 130,557,583
Number of Sequences: 237096
Number of extensions: 2842252
Number of successful extensions: 7506
Number of sequences better than 10.0: 106
Number of HSP's better than 10.0 without gapping: 5894
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6634
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 10872716010
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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