Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P09_pT_M02
(786 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
DQ148409-1|AAZ38723.1| 599|Homo sapiens ATP-binding cassette, s... 401 e-111
BT009779-1|AAP88781.1| 599|Homo sapiens ATP-binding cassette, s... 401 e-111
BC016988-1|AAH16988.1| 345|Homo sapiens Unknown (protein for IM... 401 e-111
BC016283-1|AAH16283.1| 599|Homo sapiens ATP-binding cassette, s... 401 e-111
AB062293-1|BAB93476.1| 599|Homo sapiens ATP-binding cassette su... 401 e-111
X76388-1|CAA53972.1| 599|Homo sapiens RNase L inhibitor protein. 398 e-110
X74987-1|CAA52920.1| 402|Homo sapiens endoribonuclease protein. 398 e-110
AF373328-1|AAM77558.1| 1617|Homo sapiens ABC transporter ABCA6 p... 60 1e-08
AF373290-1|AAM77557.1| 1617|Homo sapiens ABC transporter ABCA6 p... 60 1e-08
AF423346-1|AAN32752.1| 1624|Homo sapiens ATP-binding cassette su... 59 2e-08
AF423307-1|AAN32751.1| 1624|Homo sapiens ATP-binding cassette su... 59 2e-08
AY028899-1|AAK30024.1| 1624|Homo sapiens ATP-binding cassette A9... 58 3e-08
BC125232-1|AAI25233.1| 1500|Homo sapiens ABCA6 protein protein. 58 5e-08
BC125231-1|AAI25232.1| 1500|Homo sapiens ABCA6 protein protein. 58 5e-08
AY028898-1|AAK30023.1| 1617|Homo sapiens ATP-binding cassette A6... 58 5e-08
AK097296-1|BAC04994.1| 815|Homo sapiens protein ( Homo sapiens ... 58 5e-08
M55131-1|AAC13657.1| 1480|Homo sapiens cystic fibrosis transmemb... 55 3e-07
M28668-1|AAA35680.1| 1480|Homo sapiens protein ( Human cystic fi... 55 3e-07
DQ388140-1|ABD72207.1| 1480|Homo sapiens cystic fibrosis transme... 55 3e-07
DQ388138-1|ABD72203.1| 1480|Homo sapiens cystic fibrosis transme... 55 3e-07
DQ388137-1|ABD72201.1| 1480|Homo sapiens cystic fibrosis transme... 55 3e-07
DQ388135-1|ABD72197.1| 1480|Homo sapiens cystic fibrosis transme... 55 3e-07
DQ388133-1|ABD72193.1| 1480|Homo sapiens cystic fibrosis transme... 55 3e-07
DQ388132-1|ABD72191.1| 1480|Homo sapiens cystic fibrosis transme... 55 3e-07
DQ388131-1|ABD72189.1| 1480|Homo sapiens cystic fibrosis transme... 55 3e-07
DQ388130-1|ABD72187.1| 1480|Homo sapiens cystic fibrosis transme... 55 3e-07
DQ388129-1|ABD72185.1| 1480|Homo sapiens cystic fibrosis transme... 55 3e-07
DQ388128-1|ABD72183.1| 1480|Homo sapiens cystic fibrosis transme... 55 3e-07
DQ356264-1|ABC87067.1| 1480|Homo sapiens cystic fibrosis transme... 55 3e-07
DQ356263-1|ABC87065.1| 1480|Homo sapiens cystic fibrosis transme... 55 3e-07
DQ356262-1|ABC87063.1| 1480|Homo sapiens cystic fibrosis transme... 55 3e-07
DQ356261-1|ABC87061.1| 1462|Homo sapiens cystic fibrosis transme... 55 3e-07
DQ356259-1|ABC87057.1| 1480|Homo sapiens cystic fibrosis transme... 55 3e-07
DQ356258-1|ABC87055.1| 1462|Homo sapiens cystic fibrosis transme... 55 3e-07
DQ354391-1|ABC79056.1| 1480|Homo sapiens cystic fibrosis transme... 55 3e-07
DQ354390-1|ABC79054.1| 1480|Homo sapiens cystic fibrosis transme... 55 3e-07
DQ354389-1|ABC79052.1| 1480|Homo sapiens cystic fibrosis transme... 55 3e-07
DQ354388-1|ABC79050.1| 1480|Homo sapiens cystic fibrosis transme... 55 3e-07
BC130280-1|AAI30281.1| 1621|Homo sapiens ABCA8 protein protein. 55 3e-07
AB020629-1|BAA74845.2| 1591|Homo sapiens KIAA0822 protein protein. 55 3e-07
X97187-1|CAA65825.1| 1704|Homo sapiens ABC-C transporter protein. 54 8e-07
U78735-1|AAC50967.1| 1704|Homo sapiens ABC3 protein. 54 8e-07
DQ388145-1|ABD72217.1| 1480|Homo sapiens cystic fibrosis transme... 54 8e-07
DQ388144-1|ABD72215.1| 1480|Homo sapiens cystic fibrosis transme... 54 8e-07
DQ388143-1|ABD72213.1| 1480|Homo sapiens cystic fibrosis transme... 54 8e-07
DQ388142-1|ABD72211.1| 1480|Homo sapiens cystic fibrosis transme... 54 8e-07
DQ388141-1|ABD72209.1| 1480|Homo sapiens cystic fibrosis transme... 54 8e-07
DQ388139-1|ABD72205.1| 1480|Homo sapiens cystic fibrosis transme... 54 8e-07
DQ388134-1|ABD72195.1| 1480|Homo sapiens cystic fibrosis transme... 54 8e-07
DQ356260-1|ABC87059.1| 1480|Homo sapiens cystic fibrosis transme... 54 8e-07
DQ073080-1|AAY57325.1| 1704|Homo sapiens ATP-binding cassette, s... 54 8e-07
AC000111-1|AAB46352.1| 996|Homo sapiens unknown protein. 54 8e-07
AB210044-1|BAE06126.1| 1708|Homo sapiens ABCA3 variant protein p... 54 8e-07
AB070929-1|BAB86781.1| 1704|Homo sapiens lamellar body membrane ... 54 8e-07
AY028897-1|AAK30022.1| 1642|Homo sapiens ATP-binding cassette A5... 50 7e-06
AK058170-1|BAB71700.1| 364|Homo sapiens protein ( Homo sapiens ... 50 7e-06
AB067475-1|BAB67781.1| 737|Homo sapiens KIAA1888 protein protein. 50 7e-06
Y17151-1|CAA76658.2| 1527|Homo sapiens multidrug resistance prot... 50 1e-05
M23234-1|AAA36207.1| 1279|Homo sapiens protein ( Human membrane ... 50 1e-05
EF034088-1|ABJ53424.1| 1286|Homo sapiens ATP-binding cassette, s... 50 1e-05
BC042531-1|AAH42531.1| 1286|Homo sapiens ATP-binding cassette, s... 50 1e-05
AJ294545-1|CAC69553.1| 1514|Homo sapiens multidrug resistance as... 50 1e-05
AJ275973-1|CAB93535.3| 1642|Homo sapiens ATP-binding cassette pr... 50 1e-05
AF104943-1|AAD04170.1| 1527|Homo sapiens ABC transporter MOAT-D ... 50 1e-05
AF085691-1|AAD02846.1| 1238|Homo sapiens multidrug resistance-as... 50 1e-05
AF085690-1|AAD02845.1| 1527|Homo sapiens multidrug resistance-as... 50 1e-05
AF083552-1|AAC34668.1| 1527|Homo sapiens canalicular multispecif... 50 1e-05
AF009670-1|AAD01430.1| 1528|Homo sapiens MRP3 protein. 50 1e-05
AB208954-1|BAD92191.1| 1533|Homo sapiens ATP-binding cassette, s... 50 1e-05
AB010887-1|BAA28146.1| 1527|Homo sapiens multidrug resistance-as... 50 1e-05
BC051320-1|AAH51320.1| 419|Homo sapiens ABCA10 protein protein. 50 1e-05
AY247105-1|AAO72160.1| 1543|Homo sapiens ATP-binding cassette su... 50 1e-05
AY247065-1|AAO72161.1| 1543|Homo sapiens ATP-binding cassette su... 50 1e-05
AY028900-1|AAK30025.1| 1543|Homo sapiens ATP-binding cassette A1... 50 1e-05
AK056533-1|BAB71208.1| 865|Homo sapiens protein ( Homo sapiens ... 50 1e-05
BX640746-1|CAE45856.1| 431|Homo sapiens hypothetical protein pr... 49 2e-05
AJ512612-1|CAD54757.1| 925|Homo sapiens ABCA5 transporter protein. 49 2e-05
U91318-3|AAC15785.1| 848|Homo sapiens Gene product with similar... 48 3e-05
L05628-1|AAB46616.1| 1531|Homo sapiens multidrug resistance-asso... 48 3e-05
EF419769-1|ABN79590.1| 1531|Homo sapiens ATP-binding cassette, s... 48 3e-05
BC131732-1|AAI31733.1| 1503|Homo sapiens ATP-binding cassette, s... 48 3e-05
AF168791-1|AAD51293.1| 1503|Homo sapiens multi-specific organic ... 48 3e-05
AF076622-1|AAC79696.1| 1503|Homo sapiens MRP6 protein. 48 3e-05
AF022853-2|AAB83983.1| 1450|Homo sapiens multidrug resistance pr... 48 3e-05
AF022853-1|AAB83979.1| 1515|Homo sapiens multidrug resistance pr... 48 3e-05
AC003026-1|AAC05808.1| 691|Homo sapiens Multiple drug resistanc... 48 3e-05
AB209120-1|BAD92357.1| 1439|Homo sapiens ATP-binding cassette, s... 48 3e-05
BC043423-1|AAH43423.1| 301|Homo sapiens ABCB6 protein protein. 47 7e-05
BC000559-1|AAH00559.1| 842|Homo sapiens ATP-binding cassette, s... 47 7e-05
AK074491-1|BAC11021.1| 483|Homo sapiens protein ( Homo sapiens ... 47 7e-05
AK057068-1|BAB71359.1| 856|Homo sapiens protein ( Homo sapiens ... 47 7e-05
AK057026-1|BAB71347.1| 766|Homo sapiens protein ( Homo sapiens ... 47 7e-05
AJ289233-1|CAB95766.2| 842|Homo sapiens ABC transporter umat pr... 47 7e-05
AF308472-1|AAG33617.1| 896|Homo sapiens ATP-binding cassette ha... 47 7e-05
AF076775-1|AAF75107.1| 842|Homo sapiens MT-ABC transporter prot... 47 7e-05
AF070598-1|AAC28653.1| 511|Homo sapiens ABC transporter protein. 47 7e-05
AB039371-1|BAA96733.1| 842|Homo sapiens mitochondrial ABC trans... 47 7e-05
AB353947-1|BAF75364.1| 1257|Homo sapiens ATP-binding cassette, s... 47 9e-05
BT009918-1|AAP88920.1| 753|Homo sapiens ATP-binding cassette, s... 46 1e-04
BC006323-1|AAH06323.1| 753|Homo sapiens ATP-binding cassette, s... 46 1e-04
AL360179-2|CAH70564.1| 753|Homo sapiens ATP-binding cassette, s... 46 1e-04
AL360179-1|CAH70565.1| 752|Homo sapiens ATP-binding cassette, s... 46 1e-04
AL359545-2|CAI41574.1| 753|Homo sapiens ATP-binding cassette, s... 46 1e-04
AL359545-1|CAI41573.1| 752|Homo sapiens ATP-binding cassette, s... 46 1e-04
AF241887-1|AAK20173.1| 752|Homo sapiens ATP binding cassette 7 ... 46 1e-04
AF133659-1|AAD33045.1| 752|Homo sapiens ATP-binding cassette 7 ... 46 1e-04
AB005289-1|BAA28861.1| 752|Homo sapiens ABC transporter 7 prote... 46 1e-04
BC041560-1|AAH41560.1| 859|Homo sapiens ABCC4 protein protein. 46 2e-04
AY207008-1|AAO37649.1| 1325|Homo sapiens ATP-binding cassette tr... 46 2e-04
AY081219-1|AAL88745.1| 1325|Homo sapiens multidrug resistance-as... 46 2e-04
AL356257-1|CAI16722.1| 1325|Homo sapiens ATP-binding cassette, s... 46 2e-04
AL157818-1|CAC36037.2| 1325|Homo sapiens ATP-binding cassette, s... 46 2e-04
AL139381-1|CAI16589.1| 1325|Homo sapiens ATP-binding cassette, s... 46 2e-04
AF541977-1|AAN17334.1| 1278|Homo sapiens ATP-binding cassette pr... 46 2e-04
AF071203-1|AAC27077.1| 893|Homo sapiens ABC transporter MOAT-B ... 46 2e-04
AF071202-1|AAC27076.1| 1325|Homo sapiens ABC transporter MOAT-B ... 46 2e-04
AB208973-1|BAD92210.1| 776|Homo sapiens ABCC4 protein variant p... 46 2e-04
Y15635-1|CAA75729.1| 2273|Homo sapiens ABCR protein. 46 2e-04
M29447-1|AAA59576.1| 1280|Homo sapiens P glycoprotein protein. 46 2e-04
M14758-1|AAA59575.1| 1280|Homo sapiens PGY1 protein. 46 2e-04
BC130424-1|AAI30425.1| 1280|Homo sapiens ATP-binding cassette, s... 46 2e-04
AY910577-1|AAW82430.1| 1280|Homo sapiens ATP-binding cassette, s... 46 2e-04
AF016535-1|AAB69423.1| 1279|Homo sapiens P-glycoprotein protein. 46 2e-04
AF001945-1|AAC05632.1| 2273|Homo sapiens rim ABC transporter pro... 46 2e-04
AF000148-1|AAC23915.1| 2273|Homo sapiens ATP-binding cassette tr... 46 2e-04
AB210040-1|BAE06122.1| 2303|Homo sapiens ABCA4 variant protein p... 46 2e-04
AB208970-1|BAD92207.1| 1062|Homo sapiens Multidrug resistance pr... 46 2e-04
AF136523-1|AAD28285.1| 1321|Homo sapiens bile salt export pump p... 45 3e-04
AF078777-1|AAD47141.1| 748|Homo sapiens ABC transporter protein. 45 3e-04
AF328787-1|AAK00959.1| 2146|Homo sapiens ABC transporter member ... 45 4e-04
AF311102-1|AAN04657.1| 2146|Homo sapiens ABC transporter ABCA7 p... 45 4e-04
AF250238-1|AAF85794.1| 2146|Homo sapiens macrophage ABC transpor... 45 4e-04
AB055390-1|BAB62294.1| 2008|Homo sapiens ABCA-SSN protein. 45 4e-04
X06181-1|CAA29547.1| 431|Homo sapiens P-glycoprotein (431 AA) p... 44 5e-04
U88667-1|AAC51144.1| 2273|Homo sapiens ATP-binding cassette tran... 44 5e-04
BC041091-1|AAH41091.1| 646|Homo sapiens ATP-binding cassette, s... 44 5e-04
AJ308237-1|CAC87131.1| 646|Homo sapiens ABC transporter protein. 44 5e-04
AJ300465-1|CAC17140.1| 627|Homo sapiens putative white family A... 44 5e-04
AF091582-1|AAC77455.1| 1321|Homo sapiens bile salt export pump p... 44 5e-04
AC008177-1|AAY24305.1| 870|Homo sapiens unknown protein. 44 5e-04
AK172812-1|BAD18782.1| 571|Homo sapiens protein ( Homo sapiens ... 44 6e-04
BC051884-1|AAH51884.2| 709|Homo sapiens ATP-binding cassette, s... 43 0.001
BC051754-1|AAH51754.1| 709|Homo sapiens ATP-binding cassette, s... 43 0.001
BC009253-1|AAH09253.1| 709|Homo sapiens ATP-binding cassette, s... 43 0.001
AY040219-1|AAK76739.1| 1382|Homo sapiens ATP-binding cassette tr... 43 0.001
AL807752-22|CAI12768.1| 2435|Homo sapiens ATP-binding cassette, ... 43 0.001
AK092415-1|BAC03881.1| 703|Homo sapiens protein ( Homo sapiens ... 43 0.001
AK024758-1|BAB14989.1| 390|Homo sapiens protein ( Homo sapiens ... 43 0.001
AK002060-1|BAA92063.1| 709|Homo sapiens protein ( Homo sapiens ... 43 0.001
AF411579-1|AAL99902.1| 1344|Homo sapiens ATP-binding cassette pr... 43 0.001
AF367202-1|AAK58869.1| 1382|Homo sapiens ATP-binding cassette pr... 43 0.001
AF327705-1|AAK14335.1| 2436|Homo sapiens ABC transporter ABCA2 p... 43 0.001
AF327657-1|AAK14334.1| 2436|Homo sapiens ABC transporter ABCA2 p... 43 0.001
AF178941-1|AAG09372.1| 2436|Homo sapiens ATP-binding cassette su... 43 0.001
AB177854-1|BAD66832.1| 1440|Homo sapiens KIAA1062 splice variant... 43 0.001
AB028985-1|BAA83014.2| 1771|Homo sapiens KIAA1062 protein protein. 43 0.001
X96395-1|CAA65259.2| 1545|Homo sapiens canalicular multidrug res... 42 0.002
U63970-1|AAB39892.1| 1545|Homo sapiens canalicular multispecific... 42 0.002
U49248-1|AAB09422.1| 1545|Homo sapiens canalicular multispecific... 42 0.002
AL392107-3|CAI11010.1| 1545|Homo sapiens ATP-binding cassette, s... 42 0.002
AL133353-7|CAI14502.1| 1545|Homo sapiens ATP-binding cassette, s... 42 0.002
AJ132244-1|CAB45309.1| 1545|Homo sapiens multidrug resistance pr... 42 0.002
AF352582-1|AAK19755.1| 1382|Homo sapiens ATP-binding cassette tr... 42 0.002
U83661-1|AAB71758.2| 1437|Homo sapiens multidrug resistance prot... 42 0.003
BC151235-1|AAI51236.1| 718|Homo sapiens ATP-binding cassette, s... 42 0.003
BC141814-1|AAI41815.1| 718|Homo sapiens ATP-binding cassette, s... 42 0.003
AY196484-1|AAO49801.1| 1394|Homo sapiens ATP-binding cassette C5... 42 0.003
AK222911-1|BAD96631.1| 718|Homo sapiens ATP-binding cassette, s... 42 0.003
AK094636-1|BAC04392.1| 701|Homo sapiens protein ( Homo sapiens ... 42 0.003
AK002018-1|BAA92038.1| 735|Homo sapiens protein ( Homo sapiens ... 42 0.003
AF146074-1|AAD37716.1| 1437|Homo sapiens ABC protein protein. 42 0.003
AF104942-1|AAD04169.1| 1437|Homo sapiens ABC transporter MOAT-C ... 42 0.003
AF047690-1|AAD15748.1| 718|Homo sapiens ATP-binding cassette pr... 42 0.003
AB209454-1|BAD92691.1| 1430|Homo sapiens Multidrug resistance-as... 42 0.003
AB209103-1|BAD92340.1| 799|Homo sapiens ATP-binding cassette C5... 42 0.003
AB019002-1|BAA76608.1| 1437|Homo sapiens MRP5 protein. 42 0.003
AB005659-1|BAA22887.1| 946|Homo sapiens SMRP protein. 42 0.003
BC104920-1|AAI04921.1| 812|Homo sapiens ATP-binding cassette, s... 42 0.003
BC104894-1|AAI04895.2| 812|Homo sapiens ATP-binding cassette, s... 42 0.003
AY234788-1|AAO73470.1| 812|Homo sapiens P-glycoprotein ABCB5 pr... 42 0.003
AY219711-1|AAP21093.1| 2595|Homo sapiens ABCA12 transporter subf... 42 0.003
AY090613-1|AAM09027.1| 812|Homo sapiens P-glycoprotein protein. 42 0.003
AY033486-1|AAK54355.1| 2277|Homo sapiens ATP-binding cassette tr... 42 0.003
AF418105-1|AAN40735.1| 2347|Homo sapiens ATP-binding cassette tr... 42 0.003
AF399931-1|AAQ03033.1| 832|Homo sapiens P-glycoprotein protein. 42 0.003
BT007451-1|AAP36119.1| 623|Homo sapiens ATP-binding cassette, s... 41 0.006
BC001661-1|AAH01661.1| 623|Homo sapiens ATP-binding cassette, s... 41 0.006
AY851365-1|AAW31630.1| 812|Homo sapiens ABCB5beta protein. 41 0.006
AY204751-1|AAP13576.1| 5058|Homo sapiens ABC A13 protein. 41 0.006
AK131360-1|BAD18512.1| 1186|Homo sapiens mRNA. protein. 41 0.006
AJ005016-1|CAA06290.1| 550|Homo sapiens ABC transporter protein. 41 0.006
AF501281-1|AAO59914.1| 2127|Homo sapiens ATP binding cassette tr... 41 0.006
AF261092-1|AAG13903.1| 623|Homo sapiens iron inhibited ABC tran... 41 0.006
AF261091-1|AAG13902.1| 623|Homo sapiens iron inhibited ABC tran... 41 0.006
AC021097-3|AAS00379.1| 623|Homo sapiens unknown protein. 41 0.006
AC021097-2|AAS00378.1| 634|Homo sapiens unknown protein. 41 0.006
BX248518-8|CAM26017.1| 845|Homo sapiens ATP-binding cassette su... 40 0.008
BX248518-6|CAM26016.1| 807|Homo sapiens ATP-binding cassette su... 40 0.008
BX119957-4|CAM25907.1| 845|Homo sapiens ATP-binding cassette su... 40 0.008
BX119957-2|CAM25906.1| 807|Homo sapiens ATP-binding cassette su... 40 0.008
BX000357-8|CAI18562.1| 807|Homo sapiens ATP-binding cassette, s... 40 0.008
BX000357-6|CAI18563.1| 845|Homo sapiens ATP-binding cassette, s... 40 0.008
BC112923-1|AAI12924.1| 845|Homo sapiens ATP-binding cassette, s... 40 0.008
BC034488-1|AAH34488.1| 845|Homo sapiens ATP-binding cassette, s... 40 0.008
BA000025-75|BAB63325.1| 807|Homo sapiens TNFalpha-inducible ATP... 40 0.008
AL662825-7|CAI17837.1| 845|Homo sapiens ATP-binding cassette, s... 40 0.008
AL662825-6|CAI17836.1| 807|Homo sapiens ATP-binding cassette, s... 40 0.008
AL662800-8|CAI18158.1| 845|Homo sapiens ATP-binding cassette, s... 40 0.008
AL662800-7|CAI18159.1| 807|Homo sapiens ATP-binding cassette, s... 40 0.008
AK128516-1|BAC87475.1| 788|Homo sapiens protein ( Homo sapiens ... 40 0.008
AF027302-1|AAC70891.1| 807|Homo sapiens TNF-alpha stimulated AB... 40 0.008
AF022853-4|AAB83981.1| 1456|Homo sapiens multidrug resistance pr... 40 0.008
AB209564-1|BAD92801.1| 593|Homo sapiens ATP-binding cassette, s... 40 0.008
AB202093-1|BAE78612.1| 807|Homo sapiens ATP-binding cassette, s... 40 0.008
AB103602-1|BAF31263.1| 807|Homo sapiens ABC50 protein protein. 40 0.008
AB088096-1|BAC54928.1| 807|Homo sapiens ATP-binding cassette, s... 40 0.008
X91249-1|CAA62631.1| 674|Homo sapiens white protein. 40 0.013
X87344-5|CAA60785.1| 748|Homo sapiens TAP1 protein. 40 0.013
X66401-2|CAA47025.1| 748|Homo sapiens ABC-transporter protein. 40 0.013
X57522-1|CAA40741.1| 808|Homo sapiens peptide transporter protein. 40 0.013
U34919-1|AAC51098.1| 638|Homo sapiens white homolog protein. 40 0.013
U18237-1|AAA84438.1| 229|Homo sapiens ATP-binding cassette prot... 40 0.013
L21208-1|AAC12906.1| 748|Homo sapiens peptide transporter protein. 40 0.013
L21204-1|AAC12902.1| 748|Homo sapiens peptide transporter protein. 40 0.013
BX088556-4|CAM26263.1| 808|Homo sapiens transporter 1 ATP-bindi... 40 0.013
BC029158-1|AAH29158.2| 666|Homo sapiens ATP-binding cassette, s... 40 0.013
BC014081-1|AAH14081.1| 808|Homo sapiens transporter 1, ATP-bind... 40 0.013
AY048757-1|AAL06598.1| 785|Homo sapiens ATP-binding cassette tr... 40 0.013
AP001746-1|BAA95530.1| 674|Homo sapiens white protein homolog (... 40 0.013
AL935043-6|CAI18626.1| 808|Homo sapiens transporter 1, ATP-bind... 40 0.013
AL671681-12|CAI17714.1| 808|Homo sapiens transporter 1, ATP-bin... 40 0.013
AL669918-8|CAI18140.1| 808|Homo sapiens transporter 1, ATP-bind... 40 0.013
AJ289137-1|CAC00730.1| 674|Homo sapiens ATP-binding cassette tr... 40 0.013
AF323664-1|AAK28842.1| 677|Homo sapiens ATP-binding cassette tr... 40 0.013
AF323663-1|AAK28841.1| 662|Homo sapiens ATP-binding cassette tr... 40 0.013
AF323662-1|AAK28840.1| 663|Homo sapiens ATP-binding cassette tr... 40 0.013
AF323661-1|AAK28839.1| 644|Homo sapiens ATP-binding cassette tr... 40 0.013
AF323660-1|AAK28838.1| 668|Homo sapiens ATP-binding cassette tr... 40 0.013
AF323658-5|AAK28834.1| 644|Homo sapiens ATP-binding cassette tr... 40 0.013
AF323658-4|AAK28836.1| 677|Homo sapiens ATP-binding cassette tr... 40 0.013
AF323658-3|AAK28837.1| 662|Homo sapiens ATP-binding cassette tr... 40 0.013
AF323658-2|AAK28835.1| 663|Homo sapiens ATP-binding cassette tr... 40 0.013
AF323658-1|AAK28833.1| 668|Homo sapiens ATP-binding cassette tr... 40 0.013
AB038161-1|BAB13728.2| 674|Homo sapiens ABC transporter protein. 40 0.013
BC141836-1|AAI41837.1| 693|Homo sapiens ABCB8 protein protein. 39 0.018
AL359846-6|CAH73579.1| 2261|Homo sapiens ATP-binding cassette, s... 39 0.018
AL353685-3|CAH72444.1| 2261|Homo sapiens ATP-binding cassette, s... 39 0.018
AK130814-1|BAC85435.1| 546|Homo sapiens protein ( Homo sapiens ... 39 0.018
AK091270-1|BAC03623.1| 293|Homo sapiens protein ( Homo sapiens ... 39 0.018
AJ012376-1|CAA10005.1| 2201|Homo sapiens ATP-binding cassette tr... 39 0.018
AF285167-1|AAF98175.1| 2261|Homo sapiens ATP-binding cassette tr... 39 0.018
AF275948-1|AAF86276.1| 2261|Homo sapiens ABCA1 protein. 39 0.018
AF165281-1|AAD49849.1| 2201|Homo sapiens ATP cassette binding tr... 39 0.018
AC072062-1|AAY24276.1| 2413|Homo sapiens unknown protein. 39 0.018
AB055982-1|BAB63210.1| 2261|Homo sapiens ABCA1 protein. 39 0.018
BC064930-1|AAH64930.1| 738|Homo sapiens ATP-binding cassette, s... 39 0.023
AL359813-2|CAI23217.1| 1492|Homo sapiens ATP-binding cassette, s... 39 0.023
AL121990-4|CAI22012.1| 738|Homo sapiens ATP-binding cassette, s... 39 0.023
AK172794-1|BAD18770.1| 433|Homo sapiens protein ( Homo sapiens ... 39 0.023
AK000002-1|BAA92227.1| 1513|Homo sapiens FLJ00002 protein protein. 39 0.023
AF216833-1|AAF78198.1| 738|Homo sapiens M-ABC2 protein protein. 39 0.023
AB013380-1|BAB20265.1| 737|Homo sapiens mono ATP-binding casset... 39 0.023
BC047324-1|AAH47324.1| 1217|Homo sapiens structural maintenance ... 38 0.031
AL359260-2|CAI16576.1| 1217|Homo sapiens structural maintenance ... 38 0.031
AJ005015-1|CAA06289.1| 391|Homo sapiens SMC-like protein protein. 38 0.031
AF020043-1|AAC14893.1| 1217|Homo sapiens chromosome-associated p... 38 0.031
AF319622-1|AAN76500.1| 681|Homo sapiens P-glycoprotein protein. 38 0.041
AF287262-1|AAK43526.1| 2261|Homo sapiens ATP-binding cassette 1 ... 38 0.041
AC069137-4|AAY24100.1| 451|Homo sapiens unknown protein. 38 0.041
AJ278917-1|CAC07210.1| 109|Homo sapiens putative ATP-binding ca... 38 0.054
BC024103-1|AAH24103.1| 282|Homo sapiens ABCC10 protein protein. 37 0.072
AL133613-1|CAB63742.1| 700|Homo sapiens hypothetical protein pr... 37 0.072
AK024446-1|BAB15736.1| 706|Homo sapiens FLJ00036 protein protein. 37 0.072
L21207-1|AAC12905.1| 748|Homo sapiens peptide transporter protein. 37 0.095
L21206-1|AAC12904.1| 748|Homo sapiens peptide transporter protein. 37 0.095
L21205-1|AAC12903.1| 748|Homo sapiens peptide transporter protein. 37 0.095
AY523971-1|AAS55412.1| 748|Homo sapiens TAP1 protein. 37 0.095
AY523970-1|AAS55411.1| 748|Homo sapiens TAP1 protein. 37 0.095
AY851364-1|AAW31629.1| 131|Homo sapiens ABCB5alpha protein. 36 0.13
AY196326-1|AAO40749.1| 930|Homo sapiens truncated ABCC12 protei... 36 0.13
AY040220-1|AAK76740.1| 1359|Homo sapiens ATP-binding cassette tr... 36 0.13
AY032599-1|AAK39642.1| 1463|Homo sapiens multidrug resistance-as... 36 0.13
AF411578-1|AAL99901.1| 1009|Homo sapiens ATP-binding cassette pr... 36 0.13
AF411577-1|AAL99900.1| 1009|Homo sapiens ATP-binding cassette pr... 36 0.13
AF395909-1|AAL79529.1| 935|Homo sapiens ATP-binding cassette pr... 36 0.13
AF395908-1|AAL79528.1| 1009|Homo sapiens ATP-binding cassette pr... 36 0.13
AF061324-1|AAC16058.1| 1549|Homo sapiens sulfonylurea receptor 2... 36 0.13
AF061323-1|AAC16057.1| 1549|Homo sapiens sulfonylurea receptor 2... 36 0.13
AL122095-1|CAB59263.1| 216|Homo sapiens hypothetical protein pr... 36 0.17
AK024359-1|BAB14895.1| 156|Homo sapiens protein ( Homo sapiens ... 36 0.17
AC092574-2|AAY41037.1| 156|Homo sapiens unknown protein. 36 0.17
U63455-1|AAB36700.1| 1581|Homo sapiens sulfonylurea receptor pro... 36 0.22
U63421-1|AAB36699.1| 1581|Homo sapiens sulfonylurea receptor pro... 36 0.22
L78243-2|AAB02418.1| 1582|Homo sapiens SUR1 protein. 36 0.22
L78243-1|AAB02417.1| 1581|Homo sapiens SUR1 protein. 36 0.22
L78207-1|AAB02278.1| 1581|Homo sapiens sulfonylurea receptor pro... 36 0.22
AF087138-1|AAC36724.1| 1581|Homo sapiens sulfonylurea receptor 1... 36 0.22
AB209084-1|BAD92321.1| 1011|Homo sapiens Sulfonylurea receptor 1... 36 0.22
DQ388136-1|ABD72199.1| 1321|Homo sapiens cystic fibrosis transme... 35 0.29
DQ356257-1|ABC87053.1| 1480|Homo sapiens cystic fibrosis transme... 35 0.29
AK128570-1|BAC87504.1| 851|Homo sapiens protein ( Homo sapiens ... 35 0.29
AY055472-2|AAL16400.1| 54|Homo sapiens ATP-binding cassette tr... 35 0.38
AY055472-1|AAL16402.1| 57|Homo sapiens ATP-binding cassette tr... 35 0.38
U01833-1|AAA61932.1| 320|Homo sapiens protein ( Human nucleotid... 34 0.51
BC109323-1|AAI09324.1| 320|Homo sapiens nucleotide binding prot... 34 0.51
BC109322-1|AAI09323.1| 320|Homo sapiens nucleotide binding prot... 34 0.51
AL833963-1|CAD38811.1| 453|Homo sapiens hypothetical protein pr... 34 0.51
AL137481-1|CAB70762.1| 269|Homo sapiens hypothetical protein pr... 34 0.51
AK223204-1|BAD96924.1| 320|Homo sapiens nucleotide binding prot... 34 0.51
AK074738-1|BAC11171.1| 472|Homo sapiens protein ( Homo sapiens ... 34 0.51
AF216494-1|AAF89993.1| 766|Homo sapiens ATP-binding cassette pr... 34 0.51
AB177852-1|BAD66830.1| 796|Homo sapiens KIAA1520 splice variant... 34 0.51
AB045381-1|BAA97989.2| 766|Homo sapiens TAPL protein. 34 0.51
AB040953-1|BAA96044.2| 810|Homo sapiens KIAA1520 protein protein. 34 0.51
BC130385-1|AAI30386.1| 1197|Homo sapiens structural maintenance ... 34 0.67
BC064384-1|AAH64384.1| 769|Homo sapiens ABCB9 protein protein. 34 0.67
AL354938-1|CAI16923.1| 1197|Homo sapiens structural maintenance ... 34 0.67
AL161791-1|CAI16866.1| 1197|Homo sapiens structural maintenance ... 34 0.67
AF092563-1|AAC72360.1| 1197|Homo sapiens chromosome-associated p... 34 0.67
AB112582-1|BAC98409.1| 683|Homo sapiens TAP-Like isoform 12B pr... 34 0.67
DQ861369-1|ABH04443.1| 49|Homo sapiens variant ATP-binding cas... 33 0.88
DQ861356-1|ABH04430.1| 57|Homo sapiens variant ATP-binding cas... 33 1.2
BC100290-1|AAI00291.1| 309|Homo sapiens NUBP1 protein protein. 33 1.2
BC113657-1|AAI13658.1| 673|Homo sapiens ATP-binding cassette, s... 32 2.0
AF351824-1|AAK84663.1| 672|Homo sapiens sterolin-2 protein. 32 2.0
AF324494-1|AAK84078.1| 673|Homo sapiens sterolin-2 protein. 32 2.0
AF320294-1|AAG40004.1| 673|Homo sapiens ABCG8 protein. 32 2.0
AC108476-2|AAY24011.1| 673|Homo sapiens unknown protein. 32 2.0
AB112583-1|BAC98410.1| 681|Homo sapiens TAP-Like isoform 12C pr... 32 2.0
M31469-1|AAA36546.1| 216|Homo sapiens protein ( Human ras-like ... 32 2.7
L40625-1|AAA99227.1| 395|Homo sapiens sulfonylurea receptor pro... 32 2.7
CR450347-1|CAG29343.1| 216|Homo sapiens RAN protein. 32 2.7
BX248518-7|CAM26018.1| 238|Homo sapiens ATP-binding cassette su... 32 2.7
BX119957-3|CAM25908.1| 238|Homo sapiens ATP-binding cassette su... 32 2.7
BX000357-7|CAM25770.1| 238|Homo sapiens ATP-binding cassette, s... 32 2.7
BT007271-1|AAP35935.1| 216|Homo sapiens RAN, member RAS oncogen... 32 2.7
BC119677-1|AAI19678.1| 229|Homo sapiens chromosome 19 open read... 32 2.7
BC072000-1|AAH72000.1| 216|Homo sapiens RAN, member RAS oncogen... 32 2.7
BC068071-1|AAH68071.1| 229|Homo sapiens chromosome 19 open read... 32 2.7
BC051908-1|AAH51908.2| 216|Homo sapiens RAN, member RAS oncogen... 32 2.7
BC016654-1|AAH16654.1| 216|Homo sapiens RAN protein protein. 32 2.7
BC014901-1|AAH14901.1| 216|Homo sapiens RAN, member RAS oncogen... 32 2.7
BC014518-1|AAH14518.1| 216|Homo sapiens RAN, member RAS oncogen... 32 2.7
BC004272-1|AAH04272.3| 216|Homo sapiens RAN, member RAS oncogen... 32 2.7
AL662825-8|CAM25037.1| 238|Homo sapiens ATP-binding cassette, s... 32 2.7
AL662800-6|CAI18157.2| 238|Homo sapiens ATP-binding cassette, s... 32 2.7
AK092438-1|BAC03891.1| 229|Homo sapiens protein ( Homo sapiens ... 32 2.7
AK074621-1|BAC11095.1| 189|Homo sapiens protein ( Homo sapiens ... 32 2.7
AF501887-1|AAM15923.1| 216|Homo sapiens RAN small GTP binding p... 32 2.7
AF052578-1|AAC05840.1| 216|Homo sapiens androgen receptor assoc... 32 2.7
BX649189-1|CAE46207.1| 335|Homo sapiens hypothetical protein pr... 31 4.7
BC131620-1|AAI31621.1| 523|Homo sapiens dynein, cytoplasmic 1, ... 31 4.7
BC063894-1|AAH63894.1| 816|Homo sapiens DENND2C protein protein. 31 4.7
BC059361-1|AAH59361.1| 276|Homo sapiens ARL10 protein protein. 31 4.7
BC051823-1|AAH51823.1| 541|Homo sapiens EH-domain containing 4 ... 31 4.7
BC006287-1|AAH06287.1| 541|Homo sapiens EH-domain containing 4 ... 31 4.7
AL133382-1|CAM27633.1| 928|Homo sapiens DENN/MADD domain contai... 31 4.7
AK222653-1|BAD96373.1| 523|Homo sapiens dynein light chain-A va... 31 4.7
AK222573-1|BAD96293.1| 523|Homo sapiens dynein light chain-A va... 31 4.7
AK096568-1|BAC04820.1| 244|Homo sapiens protein ( Homo sapiens ... 31 4.7
AF454953-1|AAL51079.1| 541|Homo sapiens EH domain-containing pr... 31 4.7
AF323924-1|AAK11599.1| 541|Homo sapiens hepatocellular carcinom... 31 4.7
AF165306-1|AAD49852.1| 849|Homo sapiens ATP cassette binding tr... 31 4.7
Z92544-5|CAM26351.1| 618|Homo sapiens ras homolog gene family, ... 31 6.2
U16763-1|AAA89080.1| 44|Homo sapiens TAP1 protein. 31 6.2
DQ996467-1|ABI97388.1| 655|Homo sapiens ATP-binding cassette, s... 31 6.2
BC092408-1|AAH92408.1| 611|Homo sapiens ABCG2 protein protein. 31 6.2
BC021281-1|AAH21281.1| 655|Homo sapiens ATP-binding cassette, s... 31 6.2
BC014942-1|AAH14942.1| 618|Homo sapiens ras homolog gene family... 31 6.2
BA000025-79|BAB63329.1| 109|Homo sapiens TC4 protein. 31 6.2
AY333756-1|AAQ92942.1| 655|Homo sapiens ATP-binding cassette su... 31 6.2
AY333755-1|AAQ92941.1| 655|Homo sapiens mutant ATP-binding cass... 31 6.2
AY288307-1|AAP31310.1| 541|Homo sapiens ATP-binding cassette su... 31 6.2
AY207375-1|AAP46090.1| 618|Homo sapiens small G protein protein. 31 6.2
AY017168-1|AAG52982.1| 655|Homo sapiens ABC transporter ABCG2 p... 31 6.2
AJ517413-1|CAD56957.1| 618|Homo sapiens mitochondrial Rho 2 pro... 31 6.2
AF463519-1|AAO14617.1| 655|Homo sapiens ATP-binding cassette pr... 31 6.2
AF356348-1|AAL35305.1| 103|Homo sapiens breast cancer resistanc... 31 6.2
AF214736-1|AAF32285.1| 535|Homo sapiens EH domain containing pr... 31 6.2
AF181264-1|AAF40471.1| 546|Homo sapiens EH domain containing 3 ... 31 6.2
AF098951-1|AAC97367.1| 655|Homo sapiens breast cancer resistanc... 31 6.2
AF092564-1|AAC72361.1| 1202|Homo sapiens chromosome-associated p... 31 6.2
AC097484-1|AAY40902.1| 607|Homo sapiens unknown protein. 31 6.2
AB088093-1|BAC54924.1| 109|Homo sapiens RAN protein. 31 6.2
AB056867-1|BAB39212.1| 655|Homo sapiens Breast Cancer Resistanc... 31 6.2
AB051855-1|BAB46933.1| 655|Homo sapiens ATP-binding cassette su... 31 6.2
AB019987-1|BAA73535.1| 1288|Homo sapiens chromosome-associated p... 31 6.2
U07197-1|AAB60321.1| 45|Homo sapiens TAP1 protein. 30 8.2
BC104825-1|AAI04826.1| 534|Homo sapiens EH-domain containing 1 ... 30 8.2
BC104799-1|AAI04800.1| 534|Homo sapiens EH-domain containing 1 ... 30 8.2
AY007161-1|AAG02009.1| 534|Homo sapiens protein ( Homo sapiens ... 30 8.2
AK094171-1|BAC04300.1| 120|Homo sapiens protein ( Homo sapiens ... 30 8.2
AF099011-1|AAD45866.1| 534|Homo sapiens EH-domain containing pr... 30 8.2
>DQ148409-1|AAZ38723.1| 599|Homo sapiens ATP-binding cassette,
sub-family E (OABP), member 1 protein.
Length = 599
Score = 401 bits (988), Expect = e-111
Identities = 188/244 (77%), Positives = 217/244 (88%)
Frame = -3
Query: 769 YPEMXKMMGDFGLRVMPGEFSDSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLH 590
YP M K MG+F L ++ GEF+DSEI+V+LGENGTGKTTFIRMLAG L+PDEG G++P L+
Sbjct: 350 YPGMKKKMGEFELAIVAGEFTDSEIMVMLGENGTGKTTFIRMLAGRLKPDEG-GEVPVLN 408
Query: 589 ISYKPQKISPKSQGLVRSLLHDKIRDAYIHPQFLTDVMKPMKIEEIMDQEVQNLSGGELQ 410
+SYKPQKISPKS G VR LLH+KIRDAY HPQF+TDVMKP++IE I+DQEVQ LSGGELQ
Sbjct: 409 VSYKPQKISPKSTGSVRQLLHEKIRDAYTHPQFVTDVMKPLQIENIIDQEVQTLSGGELQ 468
Query: 409 RVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMATYL 230
RVAL LCLGKPADVYLIDEPSAYLDSEQRL+AA+V+KRFILHAK+T FVVEHDFIMATYL
Sbjct: 469 RVALALCLGKPADVYLIDEPSAYLDSEQRLMAARVVKRFILHAKKTAFVVEHDFIMATYL 528
Query: 229 ADRVIVFEGTPSSNATAHAPQSLLNGMNKFLELLGITFRRDPNNFRPRINKHASVKDIEQ 50
ADRVIVF+G PS N A++PQ+LL GMNKFL L ITFRRDPNN+RPRINK S+KD+EQ
Sbjct: 529 ADRVIVFDGVPSKNTVANSPQTLLAGMNKFLSQLEITFRRDPNNYRPRINKLNSIKDVEQ 588
Query: 49 KRAG 38
K++G
Sbjct: 589 KKSG 592
Score = 97.9 bits (233), Expect = 4e-20
Identities = 73/214 (34%), Positives = 111/214 (51%), Gaps = 25/214 (11%)
Frame = -3
Query: 700 EILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQKISPKSQGLVRSLLHDK 521
E+L L+G NG GK+T +++LAG +P+ G P + Q +L D
Sbjct: 104 EVLGLVGTNGIGKSTALKILAGKQKPNLGKYDDPPDWQEILTYFRGSELQNYFTKILEDD 163
Query: 520 IRDAYIHPQFLTDVMKPMK--IEEIMDQE----------------------VQNLSGGEL 413
++ A I PQ++ + K K + I+D++ V++LSGGEL
Sbjct: 164 LK-AIIKPQYVDQIPKAAKGTVGSILDRKDETKTQAIVCQQLDLTHLKERNVEDLSGGEL 222
Query: 412 QRVA-LVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMAT 236
QR A V+C+ K AD+++ DEPS+YLD +QRL AA I R +++ R VVEHD +
Sbjct: 223 QRFACAVVCIQK-ADIFMFDEPSSYLDVKQRLKAAITI-RSLINPDRYIIVVEHDLSVLD 280
Query: 235 YLADRVIVFEGTPSSNATAHAPQSLLNGMNKFLE 134
YL+D + G PS+ P S+ G+N FL+
Sbjct: 281 YLSDFICCLYGVPSAYGVVTMPFSVREGINIFLD 314
>BT009779-1|AAP88781.1| 599|Homo sapiens ATP-binding cassette,
sub-family E (OABP), member 1 protein.
Length = 599
Score = 401 bits (988), Expect = e-111
Identities = 188/244 (77%), Positives = 217/244 (88%)
Frame = -3
Query: 769 YPEMXKMMGDFGLRVMPGEFSDSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLH 590
YP M K MG+F L ++ GEF+DSEI+V+LGENGTGKTTFIRMLAG L+PDEG G++P L+
Sbjct: 350 YPGMKKKMGEFELAIVAGEFTDSEIMVMLGENGTGKTTFIRMLAGRLKPDEG-GEVPVLN 408
Query: 589 ISYKPQKISPKSQGLVRSLLHDKIRDAYIHPQFLTDVMKPMKIEEIMDQEVQNLSGGELQ 410
+SYKPQKISPKS G VR LLH+KIRDAY HPQF+TDVMKP++IE I+DQEVQ LSGGELQ
Sbjct: 409 VSYKPQKISPKSTGSVRQLLHEKIRDAYTHPQFVTDVMKPLQIENIIDQEVQTLSGGELQ 468
Query: 409 RVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMATYL 230
RVAL LCLGKPADVYLIDEPSAYLDSEQRL+AA+V+KRFILHAK+T FVVEHDFIMATYL
Sbjct: 469 RVALALCLGKPADVYLIDEPSAYLDSEQRLMAARVVKRFILHAKKTAFVVEHDFIMATYL 528
Query: 229 ADRVIVFEGTPSSNATAHAPQSLLNGMNKFLELLGITFRRDPNNFRPRINKHASVKDIEQ 50
ADRVIVF+G PS N A++PQ+LL GMNKFL L ITFRRDPNN+RPRINK S+KD+EQ
Sbjct: 529 ADRVIVFDGVPSKNTVANSPQTLLAGMNKFLSQLEITFRRDPNNYRPRINKLNSIKDVEQ 588
Query: 49 KRAG 38
K++G
Sbjct: 589 KKSG 592
Score = 97.9 bits (233), Expect = 4e-20
Identities = 73/214 (34%), Positives = 111/214 (51%), Gaps = 25/214 (11%)
Frame = -3
Query: 700 EILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQKISPKSQGLVRSLLHDK 521
E+L L+G NG GK+T +++LAG +P+ G P + Q +L D
Sbjct: 104 EVLGLVGTNGIGKSTALKILAGKQKPNLGKYDDPPDWQEILTYFRGSELQNYFTKILEDD 163
Query: 520 IRDAYIHPQFLTDVMKPMK--IEEIMDQE----------------------VQNLSGGEL 413
++ A I PQ++ + K K + I+D++ V++LSGGEL
Sbjct: 164 LK-AIIKPQYVDQIPKAAKGTVGSILDRKDETKTQAIVCQQLDLTHLKERNVEDLSGGEL 222
Query: 412 QRVA-LVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMAT 236
QR A V+C+ K AD+++ DEPS+YLD +QRL AA I R +++ R VVEHD +
Sbjct: 223 QRFACAVVCIQK-ADIFMFDEPSSYLDVKQRLKAAITI-RSLINPDRYIIVVEHDLSVLD 280
Query: 235 YLADRVIVFEGTPSSNATAHAPQSLLNGMNKFLE 134
YL+D + G PS+ P S+ G+N FL+
Sbjct: 281 YLSDFICCLYGVPSAYGVVTMPFSVREGINIFLD 314
>BC016988-1|AAH16988.1| 345|Homo sapiens Unknown (protein for
IMAGE:4396587) protein.
Length = 345
Score = 401 bits (988), Expect = e-111
Identities = 188/244 (77%), Positives = 217/244 (88%)
Frame = -3
Query: 769 YPEMXKMMGDFGLRVMPGEFSDSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLH 590
YP M K MG+F L ++ GEF+DSEI+V+LGENGTGKTTFIRMLAG L+PDEG G++P L+
Sbjct: 96 YPGMKKKMGEFELAIVAGEFTDSEIMVMLGENGTGKTTFIRMLAGRLKPDEG-GEVPVLN 154
Query: 589 ISYKPQKISPKSQGLVRSLLHDKIRDAYIHPQFLTDVMKPMKIEEIMDQEVQNLSGGELQ 410
+SYKPQKISPKS G VR LLH+KIRDAY HPQF+TDVMKP++IE I+DQEVQ LSGGELQ
Sbjct: 155 VSYKPQKISPKSTGSVRQLLHEKIRDAYTHPQFVTDVMKPLQIENIIDQEVQTLSGGELQ 214
Query: 409 RVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMATYL 230
RVAL LCLGKPADVYLIDEPSAYLDSEQRL+AA+V+KRFILHAK+T FVVEHDFIMATYL
Sbjct: 215 RVALALCLGKPADVYLIDEPSAYLDSEQRLMAARVVKRFILHAKKTAFVVEHDFIMATYL 274
Query: 229 ADRVIVFEGTPSSNATAHAPQSLLNGMNKFLELLGITFRRDPNNFRPRINKHASVKDIEQ 50
ADRVIVF+G PS N A++PQ+LL GMNKFL L ITFRRDPNN+RPRINK S+KD+EQ
Sbjct: 275 ADRVIVFDGVPSKNTVANSPQTLLAGMNKFLSQLEITFRRDPNNYRPRINKLNSIKDVEQ 334
Query: 49 KRAG 38
K++G
Sbjct: 335 KKSG 338
Score = 39.1 bits (87), Expect = 0.018
Identities = 20/60 (33%), Positives = 31/60 (51%)
Frame = -3
Query: 313 AKVIKRFILHAKRTGFVVEHDFIMATYLADRVIVFEGTPSSNATAHAPQSLLNGMNKFLE 134
A + R +++ R VVEHD + YL+D + G PS+ P S+ G+N FL+
Sbjct: 1 AAITIRSLINPDRYIIVVEHDLSVLDYLSDFICCLYGVPSAYGVVTMPFSVREGINIFLD 60
>BC016283-1|AAH16283.1| 599|Homo sapiens ATP-binding cassette,
sub-family E (OABP), member 1 protein.
Length = 599
Score = 401 bits (988), Expect = e-111
Identities = 188/244 (77%), Positives = 217/244 (88%)
Frame = -3
Query: 769 YPEMXKMMGDFGLRVMPGEFSDSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLH 590
YP M K MG+F L ++ GEF+DSEI+V+LGENGTGKTTFIRMLAG L+PDEG G++P L+
Sbjct: 350 YPGMKKKMGEFELAIVAGEFTDSEIMVMLGENGTGKTTFIRMLAGRLKPDEG-GEVPVLN 408
Query: 589 ISYKPQKISPKSQGLVRSLLHDKIRDAYIHPQFLTDVMKPMKIEEIMDQEVQNLSGGELQ 410
+SYKPQKISPKS G VR LLH+KIRDAY HPQF+TDVMKP++IE I+DQEVQ LSGGELQ
Sbjct: 409 VSYKPQKISPKSTGSVRQLLHEKIRDAYTHPQFVTDVMKPLQIENIIDQEVQTLSGGELQ 468
Query: 409 RVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMATYL 230
RVAL LCLGKPADVYLIDEPSAYLDSEQRL+AA+V+KRFILHAK+T FVVEHDFIMATYL
Sbjct: 469 RVALALCLGKPADVYLIDEPSAYLDSEQRLMAARVVKRFILHAKKTAFVVEHDFIMATYL 528
Query: 229 ADRVIVFEGTPSSNATAHAPQSLLNGMNKFLELLGITFRRDPNNFRPRINKHASVKDIEQ 50
ADRVIVF+G PS N A++PQ+LL GMNKFL L ITFRRDPNN+RPRINK S+KD+EQ
Sbjct: 529 ADRVIVFDGVPSKNTVANSPQTLLAGMNKFLSQLEITFRRDPNNYRPRINKLNSIKDVEQ 588
Query: 49 KRAG 38
K++G
Sbjct: 589 KKSG 592
Score = 97.9 bits (233), Expect = 4e-20
Identities = 73/214 (34%), Positives = 111/214 (51%), Gaps = 25/214 (11%)
Frame = -3
Query: 700 EILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQKISPKSQGLVRSLLHDK 521
E+L L+G NG GK+T +++LAG +P+ G P + Q +L D
Sbjct: 104 EVLGLVGTNGIGKSTALKILAGKQKPNLGKYDDPPDWQEILTYFRGSELQNYFTKILEDD 163
Query: 520 IRDAYIHPQFLTDVMKPMK--IEEIMDQE----------------------VQNLSGGEL 413
++ A I PQ++ + K K + I+D++ V++LSGGEL
Sbjct: 164 LK-AIIKPQYVDQIPKAAKGTVGSILDRKDETKTQAIVCQQLDLTHLKERNVEDLSGGEL 222
Query: 412 QRVA-LVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMAT 236
QR A V+C+ K AD+++ DEPS+YLD +QRL AA I R +++ R VVEHD +
Sbjct: 223 QRFACAVVCIQK-ADIFMFDEPSSYLDVKQRLKAAITI-RSLINPDRYIIVVEHDLSVLD 280
Query: 235 YLADRVIVFEGTPSSNATAHAPQSLLNGMNKFLE 134
YL+D + G PS+ P S+ G+N FL+
Sbjct: 281 YLSDFICCLYGVPSAYGVVTMPFSVREGINIFLD 314
>AB062293-1|BAB93476.1| 599|Homo sapiens ATP-binding cassette
sub-family E member 1 protein.
Length = 599
Score = 401 bits (988), Expect = e-111
Identities = 188/244 (77%), Positives = 217/244 (88%)
Frame = -3
Query: 769 YPEMXKMMGDFGLRVMPGEFSDSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLH 590
YP M K MG+F L ++ GEF+DSEI+V+LGENGTGKTTFIRMLAG L+PDEG G++P L+
Sbjct: 350 YPGMKKKMGEFELAIVAGEFTDSEIMVMLGENGTGKTTFIRMLAGRLKPDEG-GEVPVLN 408
Query: 589 ISYKPQKISPKSQGLVRSLLHDKIRDAYIHPQFLTDVMKPMKIEEIMDQEVQNLSGGELQ 410
+SYKPQKISPKS G VR LLH+KIRDAY HPQF+TDVMKP++IE I+DQEVQ LSGGELQ
Sbjct: 409 VSYKPQKISPKSTGSVRQLLHEKIRDAYTHPQFVTDVMKPLQIENIIDQEVQTLSGGELQ 468
Query: 409 RVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMATYL 230
RVAL LCLGKPADVYLIDEPSAYLDSEQRL+AA+V+KRFILHAK+T FVVEHDFIMATYL
Sbjct: 469 RVALALCLGKPADVYLIDEPSAYLDSEQRLMAARVVKRFILHAKKTAFVVEHDFIMATYL 528
Query: 229 ADRVIVFEGTPSSNATAHAPQSLLNGMNKFLELLGITFRRDPNNFRPRINKHASVKDIEQ 50
ADRVIVF+G PS N A++PQ+LL GMNKFL L ITFRRDPNN+RPRINK S+KD+EQ
Sbjct: 529 ADRVIVFDGVPSKNTVANSPQTLLAGMNKFLSQLEITFRRDPNNYRPRINKLNSIKDVEQ 588
Query: 49 KRAG 38
K++G
Sbjct: 589 KKSG 592
Score = 97.9 bits (233), Expect = 4e-20
Identities = 73/214 (34%), Positives = 111/214 (51%), Gaps = 25/214 (11%)
Frame = -3
Query: 700 EILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQKISPKSQGLVRSLLHDK 521
E+L L+G NG GK+T +++LAG +P+ G P + Q +L D
Sbjct: 104 EVLGLVGTNGIGKSTALKILAGKQKPNLGKYDDPPDWQEILTYFRGSELQNYFTKILEDD 163
Query: 520 IRDAYIHPQFLTDVMKPMK--IEEIMDQE----------------------VQNLSGGEL 413
++ A I PQ++ + K K + I+D++ V++LSGGEL
Sbjct: 164 LK-AIIKPQYVDQIPKAAKGTVGSILDRKDETKTQAIVCQQLDLTHLKERNVEDLSGGEL 222
Query: 412 QRVA-LVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMAT 236
QR A V+C+ K AD+++ DEPS+YLD +QRL AA I R +++ R VVEHD +
Sbjct: 223 QRFACAVVCIQK-ADIFMFDEPSSYLDVKQRLKAAITI-RSLINPDRYIIVVEHDLSVLD 280
Query: 235 YLADRVIVFEGTPSSNATAHAPQSLLNGMNKFLE 134
YL+D + G PS+ P S+ G+N FL+
Sbjct: 281 YLSDFICCLYGVPSAYGVVTMPFSVREGINIFLD 314
>X76388-1|CAA53972.1| 599|Homo sapiens RNase L inhibitor protein.
Length = 599
Score = 398 bits (980), Expect = e-110
Identities = 187/244 (76%), Positives = 216/244 (88%)
Frame = -3
Query: 769 YPEMXKMMGDFGLRVMPGEFSDSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLH 590
YP M K MG+F L ++ GEF+DSEI+V+LGENGTGKTTFIRMLAG L+PDEG G++P L+
Sbjct: 350 YPGMKKKMGEFELAIVAGEFTDSEIMVMLGENGTGKTTFIRMLAGRLKPDEG-GEVPVLN 408
Query: 589 ISYKPQKISPKSQGLVRSLLHDKIRDAYIHPQFLTDVMKPMKIEEIMDQEVQNLSGGELQ 410
+SYKPQKISPKS G VR LLH+KIRDAY HPQF+TDVMKP++IE I+DQEVQ LSGGELQ
Sbjct: 409 VSYKPQKISPKSTGSVRQLLHEKIRDAYTHPQFVTDVMKPLQIENIIDQEVQTLSGGELQ 468
Query: 409 RVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMATYL 230
RV L LCLGKPADVYLIDEPSAYLDSEQRL+AA+V+KRFILHAK+T FVVEHDFIMATYL
Sbjct: 469 RVRLRLCLGKPADVYLIDEPSAYLDSEQRLMAARVVKRFILHAKKTAFVVEHDFIMATYL 528
Query: 229 ADRVIVFEGTPSSNATAHAPQSLLNGMNKFLELLGITFRRDPNNFRPRINKHASVKDIEQ 50
ADRVIVF+G PS N A++PQ+LL GMNKFL L ITFRRDPNN+RPRINK S+KD+EQ
Sbjct: 529 ADRVIVFDGVPSKNTVANSPQTLLAGMNKFLSQLEITFRRDPNNYRPRINKLNSIKDVEQ 588
Query: 49 KRAG 38
K++G
Sbjct: 589 KKSG 592
Score = 93.5 bits (222), Expect = 8e-19
Identities = 71/214 (33%), Positives = 110/214 (51%), Gaps = 25/214 (11%)
Frame = -3
Query: 700 EILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQKISPKSQGLVRSLLHDK 521
E+L L+G NG GK+ +++LAG +P+ G P + Q +L D
Sbjct: 104 EVLGLVGTNGIGKSAALKILAGKQKPNLGKYDDPPDWQEILTYFRGSELQNYFTKILEDD 163
Query: 520 IRDAYIHPQFLTDVMKPMK--IEEIMDQE----------------------VQNLSGGEL 413
++ A I PQ++ ++ K + I+D++ V++LSGGEL
Sbjct: 164 LK-AIIKPQYVARFLRLAKGTVGSILDRKDETKTQAIVCQQLDLTHLKERNVEDLSGGEL 222
Query: 412 QRVA-LVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMAT 236
QR A V+C+ K AD+++ DEPS+YLD +QRL AA I R +++ R VVEHD +
Sbjct: 223 QRFACAVVCIQK-ADIFMFDEPSSYLDVKQRLKAAITI-RSLINPDRYIIVVEHDLSVLD 280
Query: 235 YLADRVIVFEGTPSSNATAHAPQSLLNGMNKFLE 134
YL+D + G PS+ P S+ G+N FL+
Sbjct: 281 YLSDFICCLYGVPSAYGVVTMPFSVREGINIFLD 314
>X74987-1|CAA52920.1| 402|Homo sapiens endoribonuclease protein.
Length = 402
Score = 398 bits (980), Expect = e-110
Identities = 187/244 (76%), Positives = 216/244 (88%)
Frame = -3
Query: 769 YPEMXKMMGDFGLRVMPGEFSDSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLH 590
YP M K MG+F L ++ GEF+DSEI+V+LGENGTGKTTFIRMLAG L+PDEG G++P L+
Sbjct: 153 YPGMKKKMGEFELAIVAGEFTDSEIMVMLGENGTGKTTFIRMLAGRLKPDEG-GEVPVLN 211
Query: 589 ISYKPQKISPKSQGLVRSLLHDKIRDAYIHPQFLTDVMKPMKIEEIMDQEVQNLSGGELQ 410
+SYKPQKISPKS G VR LLH+KIRDAY HPQF+TDVMKP++IE I+DQEVQ LSGGELQ
Sbjct: 212 VSYKPQKISPKSTGSVRQLLHEKIRDAYTHPQFVTDVMKPLQIENIIDQEVQTLSGGELQ 271
Query: 409 RVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMATYL 230
RV L LCLGKPADVYLIDEPSAYLDSEQRL+AA+V+KRFILHAK+T FVVEHDFIMATYL
Sbjct: 272 RVRLRLCLGKPADVYLIDEPSAYLDSEQRLMAARVVKRFILHAKKTAFVVEHDFIMATYL 331
Query: 229 ADRVIVFEGTPSSNATAHAPQSLLNGMNKFLELLGITFRRDPNNFRPRINKHASVKDIEQ 50
ADRVIVF+G PS N A++PQ+LL GMNKFL L ITFRRDPNN+RPRINK S+KD+EQ
Sbjct: 332 ADRVIVFDGVPSKNTVANSPQTLLAGMNKFLSQLEITFRRDPNNYRPRINKLNSIKDVEQ 391
Query: 49 KRAG 38
K++G
Sbjct: 392 KKSG 395
Score = 87.0 bits (206), Expect = 7e-17
Identities = 48/117 (41%), Positives = 73/117 (62%), Gaps = 1/117 (0%)
Frame = -3
Query: 481 VMKPMKIEEIMDQEVQNLSGGELQRVA-LVLCLGKPADVYLIDEPSAYLDSEQRLVAAKV 305
V + + + + ++ V++LSGGELQR A V+C+ K AD+++ DEPS+YLD +QRL AA
Sbjct: 3 VCQQLDLTHLKERNVEDLSGGELQRFACAVVCIQK-ADIFMFDEPSSYLDVKQRLKAAIT 61
Query: 304 IKRFILHAKRTGFVVEHDFIMATYLADRVIVFEGTPSSNATAHAPQSLLNGMNKFLE 134
I R +++ R VVEHD + YL+D + G PS+ P S+ G+N FL+
Sbjct: 62 I-RSLINPDRYIIVVEHDLSVLDYLSDFICCLYGVPSAYGVVTMPFSVREGINIFLD 117
>AF373328-1|AAM77558.1| 1617|Homo sapiens ABC transporter ABCA6
protein.
Length = 1617
Score = 59.7 bits (138), Expect = 1e-08
Identities = 49/175 (28%), Positives = 82/175 (46%), Gaps = 10/175 (5%)
Frame = -3
Query: 706 DSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQL-----HISYKPQKISPKSQGLV 542
+ EIL LLG NG GK++ IRM++G +P G +L H+ Y PQ+ +
Sbjct: 1312 EGEILGLLGPNGAGKSSSIRMISGITKPTAGEVELKGCSSVLGHLGYCPQENVLWPMLTL 1371
Query: 541 RSLLH-----DKIRDAYIHPQFLTDVMKPMKIEEIMDQEVQNLSGGELQRVALVLCLGKP 377
R L +R A + ++ K+ E ++ VQ L+ G +++ VL L
Sbjct: 1372 REHLEVYAAVKGLRKADARLA-IARLVSAFKLHEQLNVPVQKLTAGITRKLCFVLSLLGN 1430
Query: 376 ADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMATYLADRVIV 212
+ V L+DEPS +D + + I+ + + +R + H+ A L DRV +
Sbjct: 1431 SPVLLLDEPSTGIDPTGQQQMWQAIQAVVKNTERGVLLTTHNLAEAEALCDRVAI 1485
>AF373290-1|AAM77557.1| 1617|Homo sapiens ABC transporter ABCA6
protein.
Length = 1617
Score = 59.7 bits (138), Expect = 1e-08
Identities = 49/175 (28%), Positives = 82/175 (46%), Gaps = 10/175 (5%)
Frame = -3
Query: 706 DSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQL-----HISYKPQKISPKSQGLV 542
+ EIL LLG NG GK++ IRM++G +P G +L H+ Y PQ+ +
Sbjct: 1312 EGEILGLLGPNGAGKSSSIRMISGITKPTAGEVELKGCSSVLGHLGYCPQENVLWPMLTL 1371
Query: 541 RSLLH-----DKIRDAYIHPQFLTDVMKPMKIEEIMDQEVQNLSGGELQRVALVLCLGKP 377
R L +R A + ++ K+ E ++ VQ L+ G +++ VL L
Sbjct: 1372 REHLEVYAAVKGLRKADARLA-IARLVSAFKLHEQLNVPVQKLTAGITRKLCFVLSLLGN 1430
Query: 376 ADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMATYLADRVIV 212
+ V L+DEPS +D + + I+ + + +R + H+ A L DRV +
Sbjct: 1431 SPVLLLDEPSTGIDPTGQQQMWQAIQAVVKNTERGVLLTTHNLAEAEALCDRVAI 1485
>AF423346-1|AAN32752.1| 1624|Homo sapiens ATP-binding cassette
sub-family A member 9 protein.
Length = 1624
Score = 58.8 bits (136), Expect = 2e-08
Identities = 53/178 (29%), Positives = 87/178 (48%), Gaps = 15/178 (8%)
Frame = -3
Query: 700 EILVLLGENGTGKTTFIRMLAGNLEPDEGS-------GQLPQLHISYKPQKISPKSQGLV 542
E++ LLG NG GK+T I+M+ G+ +P G G P + Y PQ+ + V
Sbjct: 1320 EVIGLLGHNGAGKSTTIKMITGDTKPTAGQVILKGSGGGEPLGFLGYCPQENALWPNLTV 1379
Query: 541 RSLLH-----DKIR--DAYIHPQFLTDVMKPMKIEEIMDQEVQNLSGGELQRVALVLC-L 386
R L +R DA I +T ++ +K+++ + V+ LS G +++ VL L
Sbjct: 1380 RQHLEVYAAVKGLRKGDAMIA---ITRLVDALKLQDQLKAPVKTLSEGIKRKLCFVLSIL 1436
Query: 385 GKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMATYLADRVIV 212
G P+ V L+DEPS +D E + +VI+ + +R + H A + DRV +
Sbjct: 1437 GNPS-VVLLDEPSTGMDPEGQQQMWQVIRATFRNTERGALLTTHYMAEAEAVCDRVAI 1493
Score = 47.2 bits (107), Expect = 7e-05
Identities = 44/146 (30%), Positives = 69/146 (47%), Gaps = 18/146 (12%)
Frame = -3
Query: 706 DSEILVLLGENGTGKTTFIRMLAGNLEPDEGS--------GQLPQLHISYKPQKISPKSQ 551
+ +I LLG +G GKTT + +L+G P GS ++ + K P+S
Sbjct: 509 EGQITALLGHSGAGKTTLLNILSGLSVPTSGSVTVYNHTLSRMADIENISKFTGFCPQSN 568
Query: 550 GLVRSL-------LHDKIRDAYIHP--QFLTDVMKPMKIEEIMDQEVQNLSGGELQRVAL 398
L L KI+ H + + V++ +++E I D QNLSGG+ +++
Sbjct: 569 VQFGFLTVKENLRLFAKIKGILPHEVEKEVQRVVQELEMENIQDILAQNLSGGQNRKLTF 628
Query: 397 -VLCLGKPADVYLIDEPSAYLDSEQR 323
+ LG P V L+DEP+A LD R
Sbjct: 629 GIAILGDP-QVLLLDEPTAGLDPLSR 653
>AF423307-1|AAN32751.1| 1624|Homo sapiens ATP-binding cassette
sub-family A member 9 protein.
Length = 1624
Score = 58.8 bits (136), Expect = 2e-08
Identities = 53/178 (29%), Positives = 87/178 (48%), Gaps = 15/178 (8%)
Frame = -3
Query: 700 EILVLLGENGTGKTTFIRMLAGNLEPDEGS-------GQLPQLHISYKPQKISPKSQGLV 542
E++ LLG NG GK+T I+M+ G+ +P G G P + Y PQ+ + V
Sbjct: 1320 EVIGLLGHNGAGKSTTIKMITGDTKPTAGQVILKGSGGGEPLGFLGYCPQENALWPNLTV 1379
Query: 541 RSLLH-----DKIR--DAYIHPQFLTDVMKPMKIEEIMDQEVQNLSGGELQRVALVLC-L 386
R L +R DA I +T ++ +K+++ + V+ LS G +++ VL L
Sbjct: 1380 RQHLEVYAAVKGLRKGDAMIA---ITRLVDALKLQDQLKAPVKTLSEGIKRKLCFVLSIL 1436
Query: 385 GKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMATYLADRVIV 212
G P+ V L+DEPS +D E + +VI+ + +R + H A + DRV +
Sbjct: 1437 GNPS-VVLLDEPSTGMDPEGQQQMWQVIRATFRNTERGALLTTHYMAEAEAVCDRVAI 1493
Score = 47.2 bits (107), Expect = 7e-05
Identities = 44/146 (30%), Positives = 69/146 (47%), Gaps = 18/146 (12%)
Frame = -3
Query: 706 DSEILVLLGENGTGKTTFIRMLAGNLEPDEGS--------GQLPQLHISYKPQKISPKSQ 551
+ +I LLG +G GKTT + +L+G P GS ++ + K P+S
Sbjct: 509 EGQITALLGHSGAGKTTLLNILSGLSVPTSGSVTVYNHTLSRMADIENISKFTGFCPQSN 568
Query: 550 GLVRSL-------LHDKIRDAYIHP--QFLTDVMKPMKIEEIMDQEVQNLSGGELQRVAL 398
L L KI+ H + + V++ +++E I D QNLSGG+ +++
Sbjct: 569 VQFGFLTVKENLRLFAKIKGILPHEVEKEVQRVVQELEMENIQDILAQNLSGGQNRKLTF 628
Query: 397 -VLCLGKPADVYLIDEPSAYLDSEQR 323
+ LG P V L+DEP+A LD R
Sbjct: 629 GIAILGDP-QVLLLDEPTAGLDPLSR 653
>AY028899-1|AAK30024.1| 1624|Homo sapiens ATP-binding cassette A9
protein.
Length = 1624
Score = 58.4 bits (135), Expect = 3e-08
Identities = 53/178 (29%), Positives = 87/178 (48%), Gaps = 15/178 (8%)
Frame = -3
Query: 700 EILVLLGENGTGKTTFIRMLAGNLEPDEGS-------GQLPQLHISYKPQKISPKSQGLV 542
E++ LLG NG GK+T I+M+ G+ +P G G P + Y PQ+ + V
Sbjct: 1320 EVIGLLGHNGAGKSTTIKMITGDTKPTAGQVILKGSGGGEPLGFLGYCPQENALWPNLTV 1379
Query: 541 RSLLH-----DKIR--DAYIHPQFLTDVMKPMKIEEIMDQEVQNLSGGELQRVALVLC-L 386
R L +R DA I +T ++ +K+++ + V+ LS G +++ VL L
Sbjct: 1380 RQHLEVYAAVKGLRKGDAMIA---ITRLVDALKLQDQLKAPVKTLSEGIKRKLRFVLSIL 1436
Query: 385 GKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMATYLADRVIV 212
G P+ V L+DEPS +D E + +VI+ + +R + H A + DRV +
Sbjct: 1437 GNPS-VVLLDEPSTGMDPEGQQQMWQVIRATFRNTERGALLTTHYMAEAEAVCDRVAI 1493
Score = 47.2 bits (107), Expect = 7e-05
Identities = 44/146 (30%), Positives = 69/146 (47%), Gaps = 18/146 (12%)
Frame = -3
Query: 706 DSEILVLLGENGTGKTTFIRMLAGNLEPDEGS--------GQLPQLHISYKPQKISPKSQ 551
+ +I LLG +G GKTT + +L+G P GS ++ + K P+S
Sbjct: 509 EGQITALLGHSGAGKTTLLNILSGLSVPTSGSVTVYNHTLSRMADIENISKFTGFCPQSN 568
Query: 550 GLVRSL-------LHDKIRDAYIHP--QFLTDVMKPMKIEEIMDQEVQNLSGGELQRVAL 398
L L KI+ H + + V++ +++E I D QNLSGG+ +++
Sbjct: 569 VQFGFLTVKENLRLFAKIKGILPHEVEKEVQRVVQELEMENIQDILAQNLSGGQNRKLTF 628
Query: 397 -VLCLGKPADVYLIDEPSAYLDSEQR 323
+ LG P V L+DEP+A LD R
Sbjct: 629 GIAILGDP-QVLLLDEPTAGLDPLSR 653
>BC125232-1|AAI25233.1| 1500|Homo sapiens ABCA6 protein protein.
Length = 1500
Score = 57.6 bits (133), Expect = 5e-08
Identities = 48/175 (27%), Positives = 82/175 (46%), Gaps = 10/175 (5%)
Frame = -3
Query: 706 DSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQL-----HISYKPQKISPKSQGLV 542
+ EIL LLG +G GK++ IRM++G +P G +L H+ Y PQ+ +
Sbjct: 1312 EGEILGLLGPSGAGKSSSIRMISGITKPTAGEVELKGCSSVLGHLGYCPQENVLWPMLTL 1371
Query: 541 RSLLH-----DKIRDAYIHPQFLTDVMKPMKIEEIMDQEVQNLSGGELQRVALVLCLGKP 377
R L +R A + ++ K+ E ++ VQ L+ G +++ VL L
Sbjct: 1372 REHLEVYAAVKGLRKADARLA-IARLVSAFKLHEQLNVPVQKLTAGITRKLCFVLSLLGN 1430
Query: 376 ADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMATYLADRVIV 212
+ V L+DEPS +D + + I+ + + +R + H+ A L DRV +
Sbjct: 1431 SPVLLLDEPSTGIDPTGQQQMWQAIQAVVKNTERGVLLTTHNLAEAEALCDRVAI 1485
>BC125231-1|AAI25232.1| 1500|Homo sapiens ABCA6 protein protein.
Length = 1500
Score = 57.6 bits (133), Expect = 5e-08
Identities = 48/175 (27%), Positives = 82/175 (46%), Gaps = 10/175 (5%)
Frame = -3
Query: 706 DSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQL-----HISYKPQKISPKSQGLV 542
+ EIL LLG +G GK++ IRM++G +P G +L H+ Y PQ+ +
Sbjct: 1312 EGEILGLLGPSGAGKSSSIRMISGITKPTAGEVELKGCSSVLGHLGYCPQENVLWPMLTL 1371
Query: 541 RSLLH-----DKIRDAYIHPQFLTDVMKPMKIEEIMDQEVQNLSGGELQRVALVLCLGKP 377
R L +R A + ++ K+ E ++ VQ L+ G +++ VL L
Sbjct: 1372 REHLEVYAAVKGLRKADARLA-IARLVSAFKLHEQLNVPVQKLTAGITRKLCFVLSLLGN 1430
Query: 376 ADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMATYLADRVIV 212
+ V L+DEPS +D + + I+ + + +R + H+ A L DRV +
Sbjct: 1431 SPVLLLDEPSTGIDPTGQQQMWQAIQAVVKNTERGVLLTTHNLAEAEALCDRVAI 1485
>AY028898-1|AAK30023.1| 1617|Homo sapiens ATP-binding cassette A6
protein.
Length = 1617
Score = 57.6 bits (133), Expect = 5e-08
Identities = 48/175 (27%), Positives = 82/175 (46%), Gaps = 10/175 (5%)
Frame = -3
Query: 706 DSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQL-----HISYKPQKISPKSQGLV 542
+ EIL LLG +G GK++ IRM++G +P G +L H+ Y PQ+ +
Sbjct: 1312 EGEILGLLGPSGAGKSSSIRMISGITKPTAGEVELKGCSSVLGHLGYCPQENVLWPMLTL 1371
Query: 541 RSLLH-----DKIRDAYIHPQFLTDVMKPMKIEEIMDQEVQNLSGGELQRVALVLCLGKP 377
R L +R A + ++ K+ E ++ VQ L+ G +++ VL L
Sbjct: 1372 REHLEVYAAVKGLRKADARLA-IARLVSAFKLHEQLNVPVQKLTAGITRKLCFVLSLLGN 1430
Query: 376 ADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMATYLADRVIV 212
+ V L+DEPS +D + + I+ + + +R + H+ A L DRV +
Sbjct: 1431 SPVLLLDEPSTGIDPTGQQQMWQAIQAVVKNTERGVLLTTHNLAEAEALCDRVAI 1485
>AK097296-1|BAC04994.1| 815|Homo sapiens protein ( Homo sapiens cDNA
FLJ39977 fis, clone SPLEN2029295, moderately similar to
ATP-binding cassette, sub-family A member 8. ).
Length = 815
Score = 57.6 bits (133), Expect = 5e-08
Identities = 48/175 (27%), Positives = 82/175 (46%), Gaps = 10/175 (5%)
Frame = -3
Query: 706 DSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQL-----HISYKPQKISPKSQGLV 542
+ EIL LLG +G GK++ IRM++G +P G +L H+ Y PQ+ +
Sbjct: 510 EGEILGLLGPSGAGKSSSIRMISGITKPTAGEVELKGCSSVLGHLGYCPQENVLWPMLTL 569
Query: 541 RSLLH-----DKIRDAYIHPQFLTDVMKPMKIEEIMDQEVQNLSGGELQRVALVLCLGKP 377
R L +R A + ++ K+ E ++ VQ L+ G +++ VL L
Sbjct: 570 REHLEVYAAVKGLRKADARLA-IARLVSAFKLHEQLNVPVQKLTAGITRKLCFVLSLLGN 628
Query: 376 ADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMATYLADRVIV 212
+ V L+DEPS +D + + I+ + + +R + H+ A L DRV +
Sbjct: 629 SPVLLLDEPSTGIDPTGQQQMWQAIQAVVKNTERGVLLTTHNLAEAEALCDRVAI 683
>M55131-1|AAC13657.1| 1480|Homo sapiens cystic fibrosis
transmembrane conductance regulator protein.
Length = 1480
Score = 55.2 bits (127), Expect = 3e-07
Identities = 48/156 (30%), Positives = 80/156 (51%), Gaps = 9/156 (5%)
Frame = -3
Query: 700 EILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQK--ISPKS--QGLVRSL 533
++L + G G GKT+ + M+ G LEP EG + IS+ Q I P + + ++ +
Sbjct: 452 QLLAVAGSTGAGKTSLLMMIMGELEPSEGKIKHSG-RISFCSQFSWIMPGTIKENIIFGV 510
Query: 532 LHDKIRDAYIHP--QFLTDVMKPMKIEEIMDQEVQ-NLSGGELQRVALVLCLGKPADVYL 362
+D+ R + Q D+ K + + I+ E LSGG+ R++L + K AD+YL
Sbjct: 511 SYDEYRYRSVIKACQLEEDISKFAEKDNIVLGEGGITLSGGQRARISLARAVYKDADLYL 570
Query: 361 IDEPSAYLD--SEQRLVAAKVIKRFILHAKRTGFVV 260
+D P YLD +E+ + + V K L A +T +V
Sbjct: 571 LDSPFGYLDVLTEKEIFESCVCK---LMANKTRILV 603
>M28668-1|AAA35680.1| 1480|Homo sapiens protein ( Human cystic
fibrosis mRNA, encoding a presumed transmembrane
conductance regulator (CFTR). ).
Length = 1480
Score = 55.2 bits (127), Expect = 3e-07
Identities = 48/156 (30%), Positives = 80/156 (51%), Gaps = 9/156 (5%)
Frame = -3
Query: 700 EILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQK--ISPKS--QGLVRSL 533
++L + G G GKT+ + M+ G LEP EG + IS+ Q I P + + ++ +
Sbjct: 452 QLLAVAGSTGAGKTSLLMMIMGELEPSEGKIKHSG-RISFCSQFSWIMPGTIKENIIFGV 510
Query: 532 LHDKIRDAYIHP--QFLTDVMKPMKIEEIMDQEVQ-NLSGGELQRVALVLCLGKPADVYL 362
+D+ R + Q D+ K + + I+ E LSGG+ R++L + K AD+YL
Sbjct: 511 SYDEYRYRSVIKACQLEEDISKFAEKDNIVLGEGGITLSGGQRARISLARAVYKDADLYL 570
Query: 361 IDEPSAYLD--SEQRLVAAKVIKRFILHAKRTGFVV 260
+D P YLD +E+ + + V K L A +T +V
Sbjct: 571 LDSPFGYLDVLTEKEIFESCVCK---LMANKTRILV 603
>DQ388140-1|ABD72207.1| 1480|Homo sapiens cystic fibrosis
transmembrane conductance regulator ATP-binding cassette
sub-fa protein.
Length = 1480
Score = 55.2 bits (127), Expect = 3e-07
Identities = 48/156 (30%), Positives = 80/156 (51%), Gaps = 9/156 (5%)
Frame = -3
Query: 700 EILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQK--ISPKS--QGLVRSL 533
++L + G G GKT+ + M+ G LEP EG + IS+ Q I P + + ++ +
Sbjct: 452 QLLAVAGSTGAGKTSLLMMIMGELEPSEGKIKHSG-RISFCSQFSWIMPGTIKENIIFGV 510
Query: 532 LHDKIRDAYIHP--QFLTDVMKPMKIEEIMDQEVQ-NLSGGELQRVALVLCLGKPADVYL 362
+D+ R + Q D+ K + + I+ E LSGG+ R++L + K AD+YL
Sbjct: 511 SYDEYRYRSVIKACQLEEDISKFAEKDNIVLGEGGITLSGGQRARISLARAVYKDADLYL 570
Query: 361 IDEPSAYLD--SEQRLVAAKVIKRFILHAKRTGFVV 260
+D P YLD +E+ + + V K L A +T +V
Sbjct: 571 LDSPFGYLDVLTEKEIFESCVCK---LMANKTRILV 603
>DQ388138-1|ABD72203.1| 1480|Homo sapiens cystic fibrosis
transmembrane conductance regulator ATP-binding cassette
sub-fa protein.
Length = 1480
Score = 55.2 bits (127), Expect = 3e-07
Identities = 48/156 (30%), Positives = 80/156 (51%), Gaps = 9/156 (5%)
Frame = -3
Query: 700 EILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQK--ISPKS--QGLVRSL 533
++L + G G GKT+ + M+ G LEP EG + IS+ Q I P + + ++ +
Sbjct: 452 QLLAVAGSTGAGKTSLLMMIMGELEPSEGKIKHSG-RISFCSQFSWIMPGTIKENIIFGV 510
Query: 532 LHDKIRDAYIHP--QFLTDVMKPMKIEEIMDQEVQ-NLSGGELQRVALVLCLGKPADVYL 362
+D+ R + Q D+ K + + I+ E LSGG+ R++L + K AD+YL
Sbjct: 511 SYDEYRYRSVIKACQLEEDISKFAEKDNIVLGEGGITLSGGQRARISLARAVYKDADLYL 570
Query: 361 IDEPSAYLD--SEQRLVAAKVIKRFILHAKRTGFVV 260
+D P YLD +E+ + + V K L A +T +V
Sbjct: 571 LDSPFGYLDVLTEKEIFESCVCK---LMANKTRILV 603
>DQ388137-1|ABD72201.1| 1480|Homo sapiens cystic fibrosis
transmembrane conductance regulator ATP-binding cassette
sub-fa protein.
Length = 1480
Score = 55.2 bits (127), Expect = 3e-07
Identities = 48/156 (30%), Positives = 80/156 (51%), Gaps = 9/156 (5%)
Frame = -3
Query: 700 EILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQK--ISPKS--QGLVRSL 533
++L + G G GKT+ + M+ G LEP EG + IS+ Q I P + + ++ +
Sbjct: 452 QLLAVAGSTGAGKTSLLMMIMGELEPSEGKIKHSG-RISFCSQFSWIMPGTIKENIIFGV 510
Query: 532 LHDKIRDAYIHP--QFLTDVMKPMKIEEIMDQEVQ-NLSGGELQRVALVLCLGKPADVYL 362
+D+ R + Q D+ K + + I+ E LSGG+ R++L + K AD+YL
Sbjct: 511 SYDEYRYRSVIKACQLEEDISKFAEKDNIVLGEGGITLSGGQRARISLARAVYKDADLYL 570
Query: 361 IDEPSAYLD--SEQRLVAAKVIKRFILHAKRTGFVV 260
+D P YLD +E+ + + V K L A +T +V
Sbjct: 571 LDSPFGYLDVLTEKEIFESCVCK---LMANKTRILV 603
>DQ388135-1|ABD72197.1| 1480|Homo sapiens cystic fibrosis
transmembrane conductance regulator ATP-binding cassette
sub-fa protein.
Length = 1480
Score = 55.2 bits (127), Expect = 3e-07
Identities = 48/156 (30%), Positives = 80/156 (51%), Gaps = 9/156 (5%)
Frame = -3
Query: 700 EILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQK--ISPKS--QGLVRSL 533
++L + G G GKT+ + M+ G LEP EG + IS+ Q I P + + ++ +
Sbjct: 452 QLLAVAGSTGAGKTSLLMMIMGELEPSEGKIKHSG-RISFCSQFSWIMPGTIKENIIFGV 510
Query: 532 LHDKIRDAYIHP--QFLTDVMKPMKIEEIMDQEVQ-NLSGGELQRVALVLCLGKPADVYL 362
+D+ R + Q D+ K + + I+ E LSGG+ R++L + K AD+YL
Sbjct: 511 SYDEYRYRSVIKACQLEEDISKFAEKDNIVLGEGGITLSGGQRARISLARAVYKDADLYL 570
Query: 361 IDEPSAYLD--SEQRLVAAKVIKRFILHAKRTGFVV 260
+D P YLD +E+ + + V K L A +T +V
Sbjct: 571 LDSPFGYLDVLTEKEIFESCVCK---LMANKTRILV 603
>DQ388133-1|ABD72193.1| 1480|Homo sapiens cystic fibrosis
transmembrane conductance regulator ATP-binding cassette
sub-fa protein.
Length = 1480
Score = 55.2 bits (127), Expect = 3e-07
Identities = 48/156 (30%), Positives = 80/156 (51%), Gaps = 9/156 (5%)
Frame = -3
Query: 700 EILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQK--ISPKS--QGLVRSL 533
++L + G G GKT+ + M+ G LEP EG + IS+ Q I P + + ++ +
Sbjct: 452 QLLAVAGSTGAGKTSLLMMIMGELEPSEGKIKHSG-RISFCSQFSWIMPGTIKENIIFGV 510
Query: 532 LHDKIRDAYIHP--QFLTDVMKPMKIEEIMDQEVQ-NLSGGELQRVALVLCLGKPADVYL 362
+D+ R + Q D+ K + + I+ E LSGG+ R++L + K AD+YL
Sbjct: 511 SYDEYRYRSVIKACQLEEDISKFAEKDNIVLGEGGITLSGGQRARISLARAVYKDADLYL 570
Query: 361 IDEPSAYLD--SEQRLVAAKVIKRFILHAKRTGFVV 260
+D P YLD +E+ + + V K L A +T +V
Sbjct: 571 LDSPFGYLDVLTEKEIFESCVCK---LMANKTRILV 603
>DQ388132-1|ABD72191.1| 1480|Homo sapiens cystic fibrosis
transmembrane conductance regulator ATP-binding cassette
sub-fa protein.
Length = 1480
Score = 55.2 bits (127), Expect = 3e-07
Identities = 48/156 (30%), Positives = 80/156 (51%), Gaps = 9/156 (5%)
Frame = -3
Query: 700 EILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQK--ISPKS--QGLVRSL 533
++L + G G GKT+ + M+ G LEP EG + IS+ Q I P + + ++ +
Sbjct: 452 QLLAVAGSTGAGKTSLLMMIMGELEPSEGKIKHSG-RISFCSQFSWIMPGTIKENIIFGV 510
Query: 532 LHDKIRDAYIHP--QFLTDVMKPMKIEEIMDQEVQ-NLSGGELQRVALVLCLGKPADVYL 362
+D+ R + Q D+ K + + I+ E LSGG+ R++L + K AD+YL
Sbjct: 511 SYDEYRYRSVIKACQLEEDISKFAEKDNIVLGEGGITLSGGQRARISLARAVYKDADLYL 570
Query: 361 IDEPSAYLD--SEQRLVAAKVIKRFILHAKRTGFVV 260
+D P YLD +E+ + + V K L A +T +V
Sbjct: 571 LDSPFGYLDVLTEKEIFESCVCK---LMANKTRILV 603
>DQ388131-1|ABD72189.1| 1480|Homo sapiens cystic fibrosis
transmembrane conductance regulator ATP-binding cassette
sub-fa protein.
Length = 1480
Score = 55.2 bits (127), Expect = 3e-07
Identities = 48/156 (30%), Positives = 80/156 (51%), Gaps = 9/156 (5%)
Frame = -3
Query: 700 EILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQK--ISPKS--QGLVRSL 533
++L + G G GKT+ + M+ G LEP EG + IS+ Q I P + + ++ +
Sbjct: 452 QLLAVAGSTGAGKTSLLMMIMGELEPSEGKIKHSG-RISFCSQFSWIMPGTIKENIIFGV 510
Query: 532 LHDKIRDAYIHP--QFLTDVMKPMKIEEIMDQEVQ-NLSGGELQRVALVLCLGKPADVYL 362
+D+ R + Q D+ K + + I+ E LSGG+ R++L + K AD+YL
Sbjct: 511 SYDEYRYRSVIKACQLEEDISKFAEKDNIVLGEGGITLSGGQRARISLARAVYKDADLYL 570
Query: 361 IDEPSAYLD--SEQRLVAAKVIKRFILHAKRTGFVV 260
+D P YLD +E+ + + V K L A +T +V
Sbjct: 571 LDSPFGYLDVLTEKEIFESCVCK---LMANKTRILV 603
>DQ388130-1|ABD72187.1| 1480|Homo sapiens cystic fibrosis
transmembrane conductance regulator ATP-binding cassette
sub-fa protein.
Length = 1480
Score = 55.2 bits (127), Expect = 3e-07
Identities = 48/156 (30%), Positives = 80/156 (51%), Gaps = 9/156 (5%)
Frame = -3
Query: 700 EILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQK--ISPKS--QGLVRSL 533
++L + G G GKT+ + M+ G LEP EG + IS+ Q I P + + ++ +
Sbjct: 452 QLLAVAGSTGAGKTSLLMMIMGELEPSEGKIKHSG-RISFCSQFSWIMPGTIKENIIFGV 510
Query: 532 LHDKIRDAYIHP--QFLTDVMKPMKIEEIMDQEVQ-NLSGGELQRVALVLCLGKPADVYL 362
+D+ R + Q D+ K + + I+ E LSGG+ R++L + K AD+YL
Sbjct: 511 SYDEYRYRSVIKACQLEEDISKFAEKDNIVLGEGGITLSGGQRARISLARAVYKDADLYL 570
Query: 361 IDEPSAYLD--SEQRLVAAKVIKRFILHAKRTGFVV 260
+D P YLD +E+ + + V K L A +T +V
Sbjct: 571 LDSPFGYLDVLTEKEIFESCVCK---LMANKTRILV 603
>DQ388129-1|ABD72185.1| 1480|Homo sapiens cystic fibrosis
transmembrane conductance regulator ATP-binding cassette
sub-fa protein.
Length = 1480
Score = 55.2 bits (127), Expect = 3e-07
Identities = 48/156 (30%), Positives = 80/156 (51%), Gaps = 9/156 (5%)
Frame = -3
Query: 700 EILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQK--ISPKS--QGLVRSL 533
++L + G G GKT+ + M+ G LEP EG + IS+ Q I P + + ++ +
Sbjct: 452 QLLAVAGSTGAGKTSLLMMIMGELEPSEGKIKHSG-RISFCSQFSWIMPGTIKENIIFGV 510
Query: 532 LHDKIRDAYIHP--QFLTDVMKPMKIEEIMDQEVQ-NLSGGELQRVALVLCLGKPADVYL 362
+D+ R + Q D+ K + + I+ E LSGG+ R++L + K AD+YL
Sbjct: 511 SYDEYRYRSVIKACQLEEDISKFAEKDNIVLGEGGITLSGGQRARISLARAVYKDADLYL 570
Query: 361 IDEPSAYLD--SEQRLVAAKVIKRFILHAKRTGFVV 260
+D P YLD +E+ + + V K L A +T +V
Sbjct: 571 LDSPFGYLDVLTEKEIFESCVCK---LMANKTRILV 603
>DQ388128-1|ABD72183.1| 1480|Homo sapiens cystic fibrosis
transmembrane conductance regulator ATP-binding cassette
sub-fa protein.
Length = 1480
Score = 55.2 bits (127), Expect = 3e-07
Identities = 48/156 (30%), Positives = 80/156 (51%), Gaps = 9/156 (5%)
Frame = -3
Query: 700 EILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQK--ISPKS--QGLVRSL 533
++L + G G GKT+ + M+ G LEP EG + IS+ Q I P + + ++ +
Sbjct: 452 QLLAVAGSTGAGKTSLLMMIMGELEPSEGKIKHSG-RISFCSQFSWIMPGTIKENIIFGV 510
Query: 532 LHDKIRDAYIHP--QFLTDVMKPMKIEEIMDQEVQ-NLSGGELQRVALVLCLGKPADVYL 362
+D+ R + Q D+ K + + I+ E LSGG+ R++L + K AD+YL
Sbjct: 511 SYDEYRYRSVIKACQLEEDISKFAEKDNIVLGEGGITLSGGQRARISLARAVYKDADLYL 570
Query: 361 IDEPSAYLD--SEQRLVAAKVIKRFILHAKRTGFVV 260
+D P YLD +E+ + + V K L A +T +V
Sbjct: 571 LDSPFGYLDVLTEKEIFESCVCK---LMANKTRILV 603
>DQ356264-1|ABC87067.1| 1480|Homo sapiens cystic fibrosis
transmembrane conductance regulator ATP-binding cassette
sub-fa protein.
Length = 1480
Score = 55.2 bits (127), Expect = 3e-07
Identities = 48/156 (30%), Positives = 80/156 (51%), Gaps = 9/156 (5%)
Frame = -3
Query: 700 EILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQK--ISPKS--QGLVRSL 533
++L + G G GKT+ + M+ G LEP EG + IS+ Q I P + + ++ +
Sbjct: 452 QLLAVAGSTGAGKTSLLMMIMGELEPSEGKIKHSG-RISFCSQFSWIMPGTIKENIIFGV 510
Query: 532 LHDKIRDAYIHP--QFLTDVMKPMKIEEIMDQEVQ-NLSGGELQRVALVLCLGKPADVYL 362
+D+ R + Q D+ K + + I+ E LSGG+ R++L + K AD+YL
Sbjct: 511 SYDEYRYRSVIKACQLEEDISKFAEKDNIVLGEGGITLSGGQRARISLARAVYKDADLYL 570
Query: 361 IDEPSAYLD--SEQRLVAAKVIKRFILHAKRTGFVV 260
+D P YLD +E+ + + V K L A +T +V
Sbjct: 571 LDSPFGYLDVLTEKEIFESCVCK---LMANKTRILV 603
>DQ356263-1|ABC87065.1| 1480|Homo sapiens cystic fibrosis
transmembrane conductance regulator ATP-binding cassette
sub-fa protein.
Length = 1480
Score = 55.2 bits (127), Expect = 3e-07
Identities = 48/156 (30%), Positives = 80/156 (51%), Gaps = 9/156 (5%)
Frame = -3
Query: 700 EILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQK--ISPKS--QGLVRSL 533
++L + G G GKT+ + M+ G LEP EG + IS+ Q I P + + ++ +
Sbjct: 452 QLLAVAGSTGAGKTSLLMMIMGELEPSEGKIKHSG-RISFCSQFSWIMPGTIKENIIFGV 510
Query: 532 LHDKIRDAYIHP--QFLTDVMKPMKIEEIMDQEVQ-NLSGGELQRVALVLCLGKPADVYL 362
+D+ R + Q D+ K + + I+ E LSGG+ R++L + K AD+YL
Sbjct: 511 SYDEYRYRSVIKACQLEEDISKFAEKDNIVLGEGGITLSGGQRARISLARAVYKDADLYL 570
Query: 361 IDEPSAYLD--SEQRLVAAKVIKRFILHAKRTGFVV 260
+D P YLD +E+ + + V K L A +T +V
Sbjct: 571 LDSPFGYLDVLTEKEIFESCVCK---LMANKTRILV 603
>DQ356262-1|ABC87063.1| 1480|Homo sapiens cystic fibrosis
transmembrane conductance regulator ATP-binding cassette
sub-fa protein.
Length = 1480
Score = 55.2 bits (127), Expect = 3e-07
Identities = 48/156 (30%), Positives = 80/156 (51%), Gaps = 9/156 (5%)
Frame = -3
Query: 700 EILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQK--ISPKS--QGLVRSL 533
++L + G G GKT+ + M+ G LEP EG + IS+ Q I P + + ++ +
Sbjct: 452 QLLAVAGSTGAGKTSLLMMIMGELEPSEGKIKHSG-RISFCSQFSWIMPGTIKENIIFGV 510
Query: 532 LHDKIRDAYIHP--QFLTDVMKPMKIEEIMDQEVQ-NLSGGELQRVALVLCLGKPADVYL 362
+D+ R + Q D+ K + + I+ E LSGG+ R++L + K AD+YL
Sbjct: 511 SYDEYRYRSVIKACQLEEDISKFAEKDNIVLGEGGITLSGGQRARISLARAVYKDADLYL 570
Query: 361 IDEPSAYLD--SEQRLVAAKVIKRFILHAKRTGFVV 260
+D P YLD +E+ + + V K L A +T +V
Sbjct: 571 LDSPFGYLDVLTEKEIFESCVCK---LMANKTRILV 603
>DQ356261-1|ABC87061.1| 1462|Homo sapiens cystic fibrosis
transmembrane conductance regulator ATP-binding cassette
sub-fa protein.
Length = 1462
Score = 55.2 bits (127), Expect = 3e-07
Identities = 48/156 (30%), Positives = 80/156 (51%), Gaps = 9/156 (5%)
Frame = -3
Query: 700 EILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQK--ISPKS--QGLVRSL 533
++L + G G GKT+ + M+ G LEP EG + IS+ Q I P + + ++ +
Sbjct: 434 QLLAVAGSTGAGKTSLLMMIMGELEPSEGKIKHSG-RISFCSQFSWIMPGTIKENIIFGV 492
Query: 532 LHDKIRDAYIHP--QFLTDVMKPMKIEEIMDQEVQ-NLSGGELQRVALVLCLGKPADVYL 362
+D+ R + Q D+ K + + I+ E LSGG+ R++L + K AD+YL
Sbjct: 493 SYDEYRYRSVIKACQLEEDISKFAEKDNIVLGEGGITLSGGQRARISLARAVYKDADLYL 552
Query: 361 IDEPSAYLD--SEQRLVAAKVIKRFILHAKRTGFVV 260
+D P YLD +E+ + + V K L A +T +V
Sbjct: 553 LDSPFGYLDVLTEKEIFESCVCK---LMANKTRILV 585
>DQ356259-1|ABC87057.1| 1480|Homo sapiens cystic fibrosis
transmembrane conductance regulator ATP-binding cassette
sub-fa protein.
Length = 1480
Score = 55.2 bits (127), Expect = 3e-07
Identities = 48/156 (30%), Positives = 80/156 (51%), Gaps = 9/156 (5%)
Frame = -3
Query: 700 EILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQK--ISPKS--QGLVRSL 533
++L + G G GKT+ + M+ G LEP EG + IS+ Q I P + + ++ +
Sbjct: 452 QLLAVAGSTGAGKTSLLMMIMGELEPSEGKIKHSG-RISFCSQFSWIMPGTIKENIIFGV 510
Query: 532 LHDKIRDAYIHP--QFLTDVMKPMKIEEIMDQEVQ-NLSGGELQRVALVLCLGKPADVYL 362
+D+ R + Q D+ K + + I+ E LSGG+ R++L + K AD+YL
Sbjct: 511 SYDEYRYRSVIKACQLEEDISKFAEKDNIVLGEGGITLSGGQRARISLARAVYKDADLYL 570
Query: 361 IDEPSAYLD--SEQRLVAAKVIKRFILHAKRTGFVV 260
+D P YLD +E+ + + V K L A +T +V
Sbjct: 571 LDSPFGYLDVLTEKEIFESCVCK---LMANKTRILV 603
>DQ356258-1|ABC87055.1| 1462|Homo sapiens cystic fibrosis
transmembrane conductance regulator ATP-binding cassette
sub-fa protein.
Length = 1462
Score = 55.2 bits (127), Expect = 3e-07
Identities = 48/156 (30%), Positives = 80/156 (51%), Gaps = 9/156 (5%)
Frame = -3
Query: 700 EILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQK--ISPKS--QGLVRSL 533
++L + G G GKT+ + M+ G LEP EG + IS+ Q I P + + ++ +
Sbjct: 434 QLLAVAGSTGAGKTSLLMMIMGELEPSEGKIKHSG-RISFCSQFSWIMPGTIKENIIFGV 492
Query: 532 LHDKIRDAYIHP--QFLTDVMKPMKIEEIMDQEVQ-NLSGGELQRVALVLCLGKPADVYL 362
+D+ R + Q D+ K + + I+ E LSGG+ R++L + K AD+YL
Sbjct: 493 SYDEYRYRSVIKACQLEEDISKFAEKDNIVLGEGGITLSGGQRARISLARAVYKDADLYL 552
Query: 361 IDEPSAYLD--SEQRLVAAKVIKRFILHAKRTGFVV 260
+D P YLD +E+ + + V K L A +T +V
Sbjct: 553 LDSPFGYLDVLTEKEIFESCVCK---LMANKTRILV 585
>DQ354391-1|ABC79056.1| 1480|Homo sapiens cystic fibrosis
transmembrane conductance regulator ATP-binding cassette
sub-fa protein.
Length = 1480
Score = 55.2 bits (127), Expect = 3e-07
Identities = 48/156 (30%), Positives = 80/156 (51%), Gaps = 9/156 (5%)
Frame = -3
Query: 700 EILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQK--ISPKS--QGLVRSL 533
++L + G G GKT+ + M+ G LEP EG + IS+ Q I P + + ++ +
Sbjct: 452 QLLAVAGSTGAGKTSLLMMIMGELEPSEGKIKHSG-RISFCSQFSWIMPGTIKENIIFGV 510
Query: 532 LHDKIRDAYIHP--QFLTDVMKPMKIEEIMDQEVQ-NLSGGELQRVALVLCLGKPADVYL 362
+D+ R + Q D+ K + + I+ E LSGG+ R++L + K AD+YL
Sbjct: 511 SYDEYRYRSVIKACQLEEDISKFAEKDNIVLGEGGITLSGGQRARISLARAVYKDADLYL 570
Query: 361 IDEPSAYLD--SEQRLVAAKVIKRFILHAKRTGFVV 260
+D P YLD +E+ + + V K L A +T +V
Sbjct: 571 LDSPFGYLDVLTEKEIFESCVCK---LMANKTRILV 603
>DQ354390-1|ABC79054.1| 1480|Homo sapiens cystic fibrosis
transmembrane conductance regulator ATP-binding cassette
sub-fa protein.
Length = 1480
Score = 55.2 bits (127), Expect = 3e-07
Identities = 48/156 (30%), Positives = 80/156 (51%), Gaps = 9/156 (5%)
Frame = -3
Query: 700 EILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQK--ISPKS--QGLVRSL 533
++L + G G GKT+ + M+ G LEP EG + IS+ Q I P + + ++ +
Sbjct: 452 QLLAVAGSTGAGKTSLLMMIMGELEPSEGKIKHSG-RISFCSQFSWIMPGTIKENIIFGV 510
Query: 532 LHDKIRDAYIHP--QFLTDVMKPMKIEEIMDQEVQ-NLSGGELQRVALVLCLGKPADVYL 362
+D+ R + Q D+ K + + I+ E LSGG+ R++L + K AD+YL
Sbjct: 511 SYDEYRYRSVIKACQLEEDISKFAEKDNIVLGEGGITLSGGQRARISLARAVYKDADLYL 570
Query: 361 IDEPSAYLD--SEQRLVAAKVIKRFILHAKRTGFVV 260
+D P YLD +E+ + + V K L A +T +V
Sbjct: 571 LDSPFGYLDVLTEKEIFESCVCK---LMANKTRILV 603
>DQ354389-1|ABC79052.1| 1480|Homo sapiens cystic fibrosis
transmembrane conductance regulator ATP-binding cassette
sub-fa protein.
Length = 1480
Score = 55.2 bits (127), Expect = 3e-07
Identities = 48/156 (30%), Positives = 80/156 (51%), Gaps = 9/156 (5%)
Frame = -3
Query: 700 EILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQK--ISPKS--QGLVRSL 533
++L + G G GKT+ + M+ G LEP EG + IS+ Q I P + + ++ +
Sbjct: 452 QLLAVAGSTGAGKTSLLMMIMGELEPSEGKIKHSG-RISFCSQFSWIMPGTIKENIIFGV 510
Query: 532 LHDKIRDAYIHP--QFLTDVMKPMKIEEIMDQEVQ-NLSGGELQRVALVLCLGKPADVYL 362
+D+ R + Q D+ K + + I+ E LSGG+ R++L + K AD+YL
Sbjct: 511 SYDEYRYRSVIKACQLEEDISKFAEKDNIVLGEGGITLSGGQRARISLARAVYKDADLYL 570
Query: 361 IDEPSAYLD--SEQRLVAAKVIKRFILHAKRTGFVV 260
+D P YLD +E+ + + V K L A +T +V
Sbjct: 571 LDSPFGYLDVLTEKEIFESCVCK---LMANKTRILV 603
>DQ354388-1|ABC79050.1| 1480|Homo sapiens cystic fibrosis
transmembrane conductance regulator ATP-binding cassette
sub-fa protein.
Length = 1480
Score = 55.2 bits (127), Expect = 3e-07
Identities = 48/156 (30%), Positives = 80/156 (51%), Gaps = 9/156 (5%)
Frame = -3
Query: 700 EILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQK--ISPKS--QGLVRSL 533
++L + G G GKT+ + M+ G LEP EG + IS+ Q I P + + ++ +
Sbjct: 452 QLLAVAGSTGAGKTSLLMMIMGELEPSEGKIKHSG-RISFCSQFSWIMPGTIKENIIFGV 510
Query: 532 LHDKIRDAYIHP--QFLTDVMKPMKIEEIMDQEVQ-NLSGGELQRVALVLCLGKPADVYL 362
+D+ R + Q D+ K + + I+ E LSGG+ R++L + K AD+YL
Sbjct: 511 SYDEYRYRSVIKACQLEEDISKFAEKDNIVLGEGGITLSGGQRARISLARAVYKDADLYL 570
Query: 361 IDEPSAYLD--SEQRLVAAKVIKRFILHAKRTGFVV 260
+D P YLD +E+ + + V K L A +T +V
Sbjct: 571 LDSPFGYLDVLTEKEIFESCVCK---LMANKTRILV 603
>BC130280-1|AAI30281.1| 1621|Homo sapiens ABCA8 protein protein.
Length = 1621
Score = 55.2 bits (127), Expect = 3e-07
Identities = 49/175 (28%), Positives = 84/175 (48%), Gaps = 12/175 (6%)
Frame = -3
Query: 700 EILVLLGENGTGKTTFIRMLAGNLEPD------EGSGQLPQLH-ISYKPQKISPKSQGLV 542
E+L LLG NG GK+T I+++ G+ +P +GSG L + Y PQ+ + V
Sbjct: 1317 EVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKGSGGGDALEFLGYCPQENALWPNLTV 1376
Query: 541 RSLLHDKIRDAYIH----PQFLTDVMKPMKIEEIMDQEVQNLSGGELQRVALVL-CLGKP 377
R L + +T ++ +K+++ + V+ LS G +++ VL LG P
Sbjct: 1377 RQHLEVYAAVKGLRKGDAEVAITRLVDALKLQDQLKSPVKTLSEGIKRKLCFVLSILGNP 1436
Query: 376 ADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMATYLADRVIV 212
+ V L+DEPS +D E + + I+ + +R + H A + DRV +
Sbjct: 1437 S-VVLLDEPSTGMDPEGQQQMWQAIRATFRNTERGALLTTHYMAEAEAVCDRVAI 1490
Score = 47.2 bits (107), Expect = 7e-05
Identities = 42/146 (28%), Positives = 71/146 (48%), Gaps = 18/146 (12%)
Frame = -3
Query: 706 DSEILVLLGENGTGKTTFIRMLAGNLEPDEGS--------GQLPQLHISYKPQKISPKSQ 551
+ +I +LG +G GK+T + +L+G P +GS ++ L K + P+S
Sbjct: 508 EGQITAILGHSGAGKSTLLNILSGLSVPTKGSVTIYNNKLSEMADLENLSKLTGVCPQSN 567
Query: 550 G-----LVRSLLHDKIRDAYIHPQFLTD----VMKPMKIEEIMDQEVQNLSGGELQRVAL 398
VR L + I PQ + V+ ++++ I D QNLSGG+ +++
Sbjct: 568 VQFDFLTVRENLRLFAKIKGILPQEVDKEIQRVLLELEMKNIQDVLAQNLSGGQKRKLTF 627
Query: 397 -VLCLGKPADVYLIDEPSAYLDSEQR 323
+ LG P ++L+DEP+A LD R
Sbjct: 628 GIAILGDP-QIFLLDEPTAGLDPFSR 652
>AB020629-1|BAA74845.2| 1591|Homo sapiens KIAA0822 protein protein.
Length = 1591
Score = 55.2 bits (127), Expect = 3e-07
Identities = 49/175 (28%), Positives = 84/175 (48%), Gaps = 12/175 (6%)
Frame = -3
Query: 700 EILVLLGENGTGKTTFIRMLAGNLEPD------EGSGQLPQLH-ISYKPQKISPKSQGLV 542
E+L LLG NG GK+T I+++ G+ +P +GSG L + Y PQ+ + V
Sbjct: 1287 EVLGLLGHNGAGKSTSIKVITGDTKPTAGQVLLKGSGGGDALEFLGYCPQENALWPNLTV 1346
Query: 541 RSLLHDKIRDAYIH----PQFLTDVMKPMKIEEIMDQEVQNLSGGELQRVALVL-CLGKP 377
R L + +T ++ +K+++ + V+ LS G +++ VL LG P
Sbjct: 1347 RQHLEVYAAVKGLRKGDAEVAITRLVDALKLQDQLKSPVKTLSEGIKRKLCFVLSILGNP 1406
Query: 376 ADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMATYLADRVIV 212
+ V L+DEPS +D E + + I+ + +R + H A + DRV +
Sbjct: 1407 S-VVLLDEPSTGMDPEGQQQMWQAIRATFRNTERGALLTTHYMAEAEAVCDRVAI 1460
Score = 31.1 bits (67), Expect = 4.7
Identities = 12/32 (37%), Positives = 21/32 (65%)
Frame = -3
Query: 706 DSEILVLLGENGTGKTTFIRMLAGNLEPDEGS 611
+ +I +LG +G GK+T + +L+G P +GS
Sbjct: 518 EGQITAILGHSGAGKSTLLNILSGLSVPTKGS 549
>X97187-1|CAA65825.1| 1704|Homo sapiens ABC-C transporter protein.
Length = 1704
Score = 53.6 bits (123), Expect = 8e-07
Identities = 48/181 (26%), Positives = 85/181 (46%), Gaps = 16/181 (8%)
Frame = -3
Query: 706 DSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQKISPKSQGLV--RSL 533
+ +I VLLG NG GKTT + ML G P G + IS +I KS GL +
Sbjct: 558 EGQITVLLGHNGAGKTTTLSMLTGLFPPTSGRAYISGYEISQDMVQIR-KSLGLCPQHDI 616
Query: 532 LHDKIRDA---YIH-----------PQFLTDVMKPMKIEEIMDQEVQNLSGGELQRVALV 395
L D + A Y + P+ + ++ + +E+ + + LSGG +++++
Sbjct: 617 LFDNLTVAEHLYFYAQLKGLSRQKCPEEVKQMLHIIGLEDKWNSRSRFLSGGMRRKLSIG 676
Query: 394 LCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMATYLADRVI 215
+ L + V ++DEP++ +D+ R +++R + RT + H A L DR+
Sbjct: 677 IALIAGSKVLILDEPTSGMDAISRRAIWDLLQR--QKSDRTIVLTTHFMDEADLLGDRIA 734
Query: 214 V 212
+
Sbjct: 735 I 735
>U78735-1|AAC50967.1| 1704|Homo sapiens ABC3 protein.
Length = 1704
Score = 53.6 bits (123), Expect = 8e-07
Identities = 48/181 (26%), Positives = 85/181 (46%), Gaps = 16/181 (8%)
Frame = -3
Query: 706 DSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQKISPKSQGLV--RSL 533
+ +I VLLG NG GKTT + ML G P G + IS +I KS GL +
Sbjct: 558 EGQITVLLGHNGAGKTTTLSMLTGLFPPTSGRAYISGYEISQDMVQIR-KSLGLCPQHDI 616
Query: 532 LHDKIRDA---YIH-----------PQFLTDVMKPMKIEEIMDQEVQNLSGGELQRVALV 395
L D + A Y + P+ + ++ + +E+ + + LSGG +++++
Sbjct: 617 LFDNLTVAEHLYFYAQLKGLSRQKCPEEVKQMLHIIGLEDKWNSRSRFLSGGMRRKLSIG 676
Query: 394 LCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMATYLADRVI 215
+ L + V ++DEP++ +D+ R +++R + RT + H A L DR+
Sbjct: 677 IALIAGSKVLILDEPTSGMDAISRRAIWDLLQR--QKSDRTIVLTTHFMDEADLLGDRIA 734
Query: 214 V 212
+
Sbjct: 735 I 735
>DQ388145-1|ABD72217.1| 1480|Homo sapiens cystic fibrosis
transmembrane conductance regulator ATP-binding cassette
sub-fa protein.
Length = 1480
Score = 53.6 bits (123), Expect = 8e-07
Identities = 47/156 (30%), Positives = 80/156 (51%), Gaps = 9/156 (5%)
Frame = -3
Query: 700 EILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQK--ISPKS--QGLVRSL 533
++L + G G GKT+ + ++ G LEP EG + IS+ Q I P + + ++ +
Sbjct: 452 QLLAVAGSTGAGKTSLLMVIMGELEPSEGKIKHSG-RISFCSQFSWIMPGTIKENIIFGV 510
Query: 532 LHDKIRDAYIHP--QFLTDVMKPMKIEEIMDQEVQ-NLSGGELQRVALVLCLGKPADVYL 362
+D+ R + Q D+ K + + I+ E LSGG+ R++L + K AD+YL
Sbjct: 511 SYDEYRYRSVIKACQLEEDISKFAEKDNIVLGEGGITLSGGQRARISLARAVYKDADLYL 570
Query: 361 IDEPSAYLD--SEQRLVAAKVIKRFILHAKRTGFVV 260
+D P YLD +E+ + + V K L A +T +V
Sbjct: 571 LDSPFGYLDVLTEKEIFESCVCK---LMANKTRILV 603
>DQ388144-1|ABD72215.1| 1480|Homo sapiens cystic fibrosis
transmembrane conductance regulator ATP-binding cassette
sub-fa protein.
Length = 1480
Score = 53.6 bits (123), Expect = 8e-07
Identities = 47/156 (30%), Positives = 80/156 (51%), Gaps = 9/156 (5%)
Frame = -3
Query: 700 EILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQK--ISPKS--QGLVRSL 533
++L + G G GKT+ + ++ G LEP EG + IS+ Q I P + + ++ +
Sbjct: 452 QLLAVAGSTGAGKTSLLMVIMGELEPSEGKIKHSG-RISFCSQFSWIMPGTIKENIIFGV 510
Query: 532 LHDKIRDAYIHP--QFLTDVMKPMKIEEIMDQEVQ-NLSGGELQRVALVLCLGKPADVYL 362
+D+ R + Q D+ K + + I+ E LSGG+ R++L + K AD+YL
Sbjct: 511 SYDEYRYRSVIKACQLEEDISKFAEKDNIVLGEGGITLSGGQRARISLARAVYKDADLYL 570
Query: 361 IDEPSAYLD--SEQRLVAAKVIKRFILHAKRTGFVV 260
+D P YLD +E+ + + V K L A +T +V
Sbjct: 571 LDSPFGYLDVLTEKEIFESCVCK---LMANKTRILV 603
>DQ388143-1|ABD72213.1| 1480|Homo sapiens cystic fibrosis
transmembrane conductance regulator ATP-binding cassette
sub-fa protein.
Length = 1480
Score = 53.6 bits (123), Expect = 8e-07
Identities = 47/156 (30%), Positives = 80/156 (51%), Gaps = 9/156 (5%)
Frame = -3
Query: 700 EILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQK--ISPKS--QGLVRSL 533
++L + G G GKT+ + ++ G LEP EG + IS+ Q I P + + ++ +
Sbjct: 452 QLLAVAGSTGAGKTSLLMVIMGELEPSEGKIKHSG-RISFCSQFSWIMPGTIKENIIFGV 510
Query: 532 LHDKIRDAYIHP--QFLTDVMKPMKIEEIMDQEVQ-NLSGGELQRVALVLCLGKPADVYL 362
+D+ R + Q D+ K + + I+ E LSGG+ R++L + K AD+YL
Sbjct: 511 SYDEYRYRSVIKACQLEEDISKFAEKDNIVLGEGGITLSGGQRARISLARAVYKDADLYL 570
Query: 361 IDEPSAYLD--SEQRLVAAKVIKRFILHAKRTGFVV 260
+D P YLD +E+ + + V K L A +T +V
Sbjct: 571 LDSPFGYLDVLTEKEIFESCVCK---LMANKTRILV 603
>DQ388142-1|ABD72211.1| 1480|Homo sapiens cystic fibrosis
transmembrane conductance regulator ATP-binding cassette
sub-fa protein.
Length = 1480
Score = 53.6 bits (123), Expect = 8e-07
Identities = 47/156 (30%), Positives = 80/156 (51%), Gaps = 9/156 (5%)
Frame = -3
Query: 700 EILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQK--ISPKS--QGLVRSL 533
++L + G G GKT+ + ++ G LEP EG + IS+ Q I P + + ++ +
Sbjct: 452 QLLAVAGSTGAGKTSLLMVIMGELEPSEGKIKHSG-RISFCSQFSWIMPGTIKENIIFGV 510
Query: 532 LHDKIRDAYIHP--QFLTDVMKPMKIEEIMDQEVQ-NLSGGELQRVALVLCLGKPADVYL 362
+D+ R + Q D+ K + + I+ E LSGG+ R++L + K AD+YL
Sbjct: 511 SYDEYRYRSVIKACQLEEDISKFAEKDNIVLGEGGITLSGGQRARISLARAVYKDADLYL 570
Query: 361 IDEPSAYLD--SEQRLVAAKVIKRFILHAKRTGFVV 260
+D P YLD +E+ + + V K L A +T +V
Sbjct: 571 LDSPFGYLDVLTEKEIFESCVCK---LMANKTRILV 603
>DQ388141-1|ABD72209.1| 1480|Homo sapiens cystic fibrosis
transmembrane conductance regulator ATP-binding cassette
sub-fa protein.
Length = 1480
Score = 53.6 bits (123), Expect = 8e-07
Identities = 47/156 (30%), Positives = 80/156 (51%), Gaps = 9/156 (5%)
Frame = -3
Query: 700 EILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQK--ISPKS--QGLVRSL 533
++L + G G GKT+ + ++ G LEP EG + IS+ Q I P + + ++ +
Sbjct: 452 QLLAVAGSTGAGKTSLLMVIMGELEPSEGKIKHSG-RISFCSQFSWIMPGTIKENIIFGV 510
Query: 532 LHDKIRDAYIHP--QFLTDVMKPMKIEEIMDQEVQ-NLSGGELQRVALVLCLGKPADVYL 362
+D+ R + Q D+ K + + I+ E LSGG+ R++L + K AD+YL
Sbjct: 511 SYDEYRYRSVIKACQLEEDISKFAEKDNIVLGEGGITLSGGQRARISLARAVYKDADLYL 570
Query: 361 IDEPSAYLD--SEQRLVAAKVIKRFILHAKRTGFVV 260
+D P YLD +E+ + + V K L A +T +V
Sbjct: 571 LDSPFGYLDVLTEKEIFESCVCK---LMANKTRILV 603
>DQ388139-1|ABD72205.1| 1480|Homo sapiens cystic fibrosis
transmembrane conductance regulator ATP-binding cassette
sub-fa protein.
Length = 1480
Score = 53.6 bits (123), Expect = 8e-07
Identities = 47/156 (30%), Positives = 80/156 (51%), Gaps = 9/156 (5%)
Frame = -3
Query: 700 EILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQK--ISPKS--QGLVRSL 533
++L + G G GKT+ + ++ G LEP EG + IS+ Q I P + + ++ +
Sbjct: 452 QLLAVAGSTGAGKTSLLMVIMGELEPSEGKIKHSG-RISFCSQFSWIMPGTIKENIIFGV 510
Query: 532 LHDKIRDAYIHP--QFLTDVMKPMKIEEIMDQEVQ-NLSGGELQRVALVLCLGKPADVYL 362
+D+ R + Q D+ K + + I+ E LSGG+ R++L + K AD+YL
Sbjct: 511 SYDEYRYRSVIKACQLEEDISKFAEKDNIVLGEGGITLSGGQRARISLARAVYKDADLYL 570
Query: 361 IDEPSAYLD--SEQRLVAAKVIKRFILHAKRTGFVV 260
+D P YLD +E+ + + V K L A +T +V
Sbjct: 571 LDSPFGYLDVLTEKEIFESCVCK---LMANKTRILV 603
>DQ388134-1|ABD72195.1| 1480|Homo sapiens cystic fibrosis
transmembrane conductance regulator ATP-binding cassette
sub-fa protein.
Length = 1480
Score = 53.6 bits (123), Expect = 8e-07
Identities = 47/156 (30%), Positives = 80/156 (51%), Gaps = 9/156 (5%)
Frame = -3
Query: 700 EILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQK--ISPKS--QGLVRSL 533
++L + G G GKT+ + ++ G LEP EG + IS+ Q I P + + ++ +
Sbjct: 452 QLLAVAGSTGAGKTSLLMVIMGELEPSEGKIKHSG-RISFCSQFSWIMPGTIKENIIFGV 510
Query: 532 LHDKIRDAYIHP--QFLTDVMKPMKIEEIMDQEVQ-NLSGGELQRVALVLCLGKPADVYL 362
+D+ R + Q D+ K + + I+ E LSGG+ R++L + K AD+YL
Sbjct: 511 SYDEYRYRSVIKACQLEEDISKFAEKDNIVLGEGGITLSGGQRARISLARAVYKDADLYL 570
Query: 361 IDEPSAYLD--SEQRLVAAKVIKRFILHAKRTGFVV 260
+D P YLD +E+ + + V K L A +T +V
Sbjct: 571 LDSPFGYLDVLTEKEIFESCVCK---LMANKTRILV 603
>DQ356260-1|ABC87059.1| 1480|Homo sapiens cystic fibrosis
transmembrane conductance regulator ATP-binding cassette
sub-fa protein.
Length = 1480
Score = 53.6 bits (123), Expect = 8e-07
Identities = 47/156 (30%), Positives = 80/156 (51%), Gaps = 9/156 (5%)
Frame = -3
Query: 700 EILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQK--ISPKS--QGLVRSL 533
++L + G G GKT+ + ++ G LEP EG + IS+ Q I P + + ++ +
Sbjct: 452 QLLAVAGSTGAGKTSLLMVIMGELEPSEGKIKHSG-RISFCSQFSWIMPGTIKENIIFGV 510
Query: 532 LHDKIRDAYIHP--QFLTDVMKPMKIEEIMDQEVQ-NLSGGELQRVALVLCLGKPADVYL 362
+D+ R + Q D+ K + + I+ E LSGG+ R++L + K AD+YL
Sbjct: 511 SYDEYRYRSVIKACQLEEDISKFAEKDNIVLGEGGITLSGGQRARISLARAVYKDADLYL 570
Query: 361 IDEPSAYLD--SEQRLVAAKVIKRFILHAKRTGFVV 260
+D P YLD +E+ + + V K L A +T +V
Sbjct: 571 LDSPFGYLDVLTEKEIFESCVCK---LMANKTRILV 603
>DQ073080-1|AAY57325.1| 1704|Homo sapiens ATP-binding cassette,
sub-family A (ABC1), member 3 protein.
Length = 1704
Score = 53.6 bits (123), Expect = 8e-07
Identities = 48/181 (26%), Positives = 85/181 (46%), Gaps = 16/181 (8%)
Frame = -3
Query: 706 DSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQKISPKSQGLV--RSL 533
+ +I VLLG NG GKTT + ML G P G + IS +I KS GL +
Sbjct: 558 EGQITVLLGHNGAGKTTTLSMLTGLFPPTSGRAYISGYEISQDMVQIR-KSLGLCPQHDI 616
Query: 532 LHDKIRDA---YIH-----------PQFLTDVMKPMKIEEIMDQEVQNLSGGELQRVALV 395
L D + A Y + P+ + ++ + +E+ + + LSGG +++++
Sbjct: 617 LFDNLTVAEHLYFYAQLKGLSRQKCPEEVKQMLHIIGLEDKWNSRSRFLSGGMRRKLSIG 676
Query: 394 LCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMATYLADRVI 215
+ L + V ++DEP++ +D+ R +++R + RT + H A L DR+
Sbjct: 677 IALIAGSKVLILDEPTSGMDAISRRAIWDLLQR--QKSDRTIVLTTHFMDEADLLGDRIA 734
Query: 214 V 212
+
Sbjct: 735 I 735
>AC000111-1|AAB46352.1| 996|Homo sapiens unknown protein.
Length = 996
Score = 53.6 bits (123), Expect = 8e-07
Identities = 47/156 (30%), Positives = 80/156 (51%), Gaps = 9/156 (5%)
Frame = -3
Query: 700 EILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQK--ISPKS--QGLVRSL 533
++L + G G GKT+ + ++ G LEP EG + IS+ Q I P + + ++ +
Sbjct: 452 QLLAVAGSTGAGKTSLLMVIMGELEPSEGKIKHSG-RISFCSQFSWIMPGTIKENIIFGV 510
Query: 532 LHDKIRDAYIHP--QFLTDVMKPMKIEEIMDQEVQ-NLSGGELQRVALVLCLGKPADVYL 362
+D+ R + Q D+ K + + I+ E LSGG+ R++L + K AD+YL
Sbjct: 511 SYDEYRYRSVIKACQLEEDISKFAEKDNIVLGEGGITLSGGQRARISLARAVYKDADLYL 570
Query: 361 IDEPSAYLD--SEQRLVAAKVIKRFILHAKRTGFVV 260
+D P YLD +E+ + + V K L A +T +V
Sbjct: 571 LDSPFGYLDVLTEKEIFESCVCK---LMANKTRILV 603
>AB210044-1|BAE06126.1| 1708|Homo sapiens ABCA3 variant protein
protein.
Length = 1708
Score = 53.6 bits (123), Expect = 8e-07
Identities = 48/181 (26%), Positives = 85/181 (46%), Gaps = 16/181 (8%)
Frame = -3
Query: 706 DSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQKISPKSQGLV--RSL 533
+ +I VLLG NG GKTT + ML G P G + IS +I KS GL +
Sbjct: 562 EGQITVLLGHNGAGKTTTLSMLTGLFPPTSGRAYISGYEISQDMVQIR-KSLGLCPQHDI 620
Query: 532 LHDKIRDA---YIH-----------PQFLTDVMKPMKIEEIMDQEVQNLSGGELQRVALV 395
L D + A Y + P+ + ++ + +E+ + + LSGG +++++
Sbjct: 621 LFDNLTVAEHLYFYAQLKGLSRQKCPEEVKQMLHIIGLEDKWNSRSRFLSGGMRRKLSIG 680
Query: 394 LCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMATYLADRVI 215
+ L + V ++DEP++ +D+ R +++R + RT + H A L DR+
Sbjct: 681 IALIAGSKVLILDEPTSGMDAISRRAIWDLLQR--QKSDRTIVLTTHFMDEADLLGDRIA 738
Query: 214 V 212
+
Sbjct: 739 I 739
>AB070929-1|BAB86781.1| 1704|Homo sapiens lamellar body membrane
specific ATP-binding cassette protein protein.
Length = 1704
Score = 53.6 bits (123), Expect = 8e-07
Identities = 48/181 (26%), Positives = 85/181 (46%), Gaps = 16/181 (8%)
Frame = -3
Query: 706 DSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQKISPKSQGLV--RSL 533
+ +I VLLG NG GKTT + ML G P G + IS +I KS GL +
Sbjct: 558 EGQITVLLGHNGAGKTTTLSMLTGLFPPTSGRAYISGYEISQDMVQIR-KSLGLCPQHDI 616
Query: 532 LHDKIRDA---YIH-----------PQFLTDVMKPMKIEEIMDQEVQNLSGGELQRVALV 395
L D + A Y + P+ + ++ + +E+ + + LSGG +++++
Sbjct: 617 LFDNLTVAEHLYFYAQLKGLSRQKCPEEVKQMLHIIGLEDKWNSRSRFLSGGMRRKLSIG 676
Query: 394 LCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMATYLADRVI 215
+ L + V ++DEP++ +D+ R +++R + RT + H A L DR+
Sbjct: 677 IALIAGSKVLILDEPTSGMDAISRRAIWDLLQR--QKSDRTIVLTTHFMDEADLLGDRIA 734
Query: 214 V 212
+
Sbjct: 735 I 735
>AY028897-1|AAK30022.1| 1642|Homo sapiens ATP-binding cassette A5
protein.
Length = 1642
Score = 50.4 bits (115), Expect = 7e-06
Identities = 47/180 (26%), Positives = 76/180 (42%), Gaps = 17/180 (9%)
Frame = -3
Query: 700 EILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQKISPKSQGL---VRSLL 530
EIL LLG NG GK+T I +L G++EP G L S K G + L
Sbjct: 1327 EILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYSSETSEDDDSLKCMGYCPQINPLW 1386
Query: 529 HD-------------KIRDAYIHPQFLTDVMKPMKIEEIMDQEVQNLSGGELQRVALVL- 392
D K A + ++ + + ++E + + V+ L G +++ L
Sbjct: 1387 PDTTLQEHFEIYGAVKGMSASDMKEVISRITHALDLKEHLQKTVKKLPAGIKRKLCFALS 1446
Query: 391 CLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMATYLADRVIV 212
LG P + L+DEPS +D + + + I+ + KR + H A + DRV +
Sbjct: 1447 MLGNP-QITLLDEPSTGMDPKAKQHMWRAIRTAFKNRKRAAILTTHYMEEAEAVCDRVAI 1505
Score = 49.2 bits (112), Expect = 2e-05
Identities = 48/192 (25%), Positives = 84/192 (43%), Gaps = 18/192 (9%)
Frame = -3
Query: 733 LRVMPGEFSDSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQKISPKS 554
LR + + + +I LLG +GTGK+T + +L G P +G + +S + +
Sbjct: 497 LRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDEMFEARK 556
Query: 553 Q-GLVRSL-LHDKIRDAYIHPQFLTD---------------VMKPMKIEEIMDQEVQNLS 425
G+ L +H + + L V+ + ++ I D + + LS
Sbjct: 557 MIGICPQLDIHFDVLTVEENLSILASIKGIPANNIIQEVQKVLLDLDMQTIKDNQAKKLS 616
Query: 424 GGELQRVAL-VLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDF 248
GG+ ++++L + LG P + L+DEP+A +D R + ++K A R H
Sbjct: 617 GGQKRKLSLGIAVLGNPK-ILLLDEPTAGMDPCSRHIVWNLLK--YRKANRVTVFSTHFM 673
Query: 247 IMATYLADRVIV 212
A LADR V
Sbjct: 674 DEADILADRKAV 685
>AK058170-1|BAB71700.1| 364|Homo sapiens protein ( Homo sapiens
cDNA FLJ25441 fis, clone TST08455. ).
Length = 364
Score = 50.4 bits (115), Expect = 7e-06
Identities = 47/180 (26%), Positives = 76/180 (42%), Gaps = 17/180 (9%)
Frame = -3
Query: 700 EILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQKISPKSQGL---VRSLL 530
EIL LLG NG GK+T I +L G++EP G L S K G + L
Sbjct: 49 EILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYSSETSEDDDSLKCMGYCPQINPLW 108
Query: 529 HD-------------KIRDAYIHPQFLTDVMKPMKIEEIMDQEVQNLSGGELQRVALVL- 392
D K A + ++ + + ++E + + V+ L G +++ L
Sbjct: 109 PDTTLQEHFEIYGAVKGMSASDMKEVISRITHALDLKEHLQKTVKKLPAGIKRKLCFALS 168
Query: 391 CLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMATYLADRVIV 212
LG P + L+DEPS +D + + + I+ + KR + H A + DRV +
Sbjct: 169 MLGNP-QITLLDEPSTGMDPKAKQHMWRAIRTAFKNRKRAAILTTHYMEEAEAVCDRVAI 227
>AB067475-1|BAB67781.1| 737|Homo sapiens KIAA1888 protein protein.
Length = 737
Score = 50.4 bits (115), Expect = 7e-06
Identities = 47/180 (26%), Positives = 76/180 (42%), Gaps = 17/180 (9%)
Frame = -3
Query: 700 EILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQKISPKSQGL---VRSLL 530
EIL LLG NG GK+T I +L G++EP G L S K G + L
Sbjct: 422 EILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYSSETSEDDDSLKCMGYCPQINPLW 481
Query: 529 HD-------------KIRDAYIHPQFLTDVMKPMKIEEIMDQEVQNLSGGELQRVALVL- 392
D K A + ++ + + ++E + + V+ L G +++ L
Sbjct: 482 PDTTLQEHFEIYGAVKGMSASDMKEVISRITHALDLKEHLQKTVKKLPAGIKRKLCFALS 541
Query: 391 CLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMATYLADRVIV 212
LG P + L+DEPS +D + + + I+ + KR + H A + DRV +
Sbjct: 542 MLGNP-QITLLDEPSTGMDPKAKQHMWRAIRTAFKNRKRAAILTTHYMEEAEAVCDRVAI 600
>Y17151-1|CAA76658.2| 1527|Homo sapiens multidrug resistance protein 3
(ABCC3) protein.
Length = 1527
Score = 50.0 bits (114), Expect = 1e-05
Identities = 36/129 (27%), Positives = 68/129 (52%), Gaps = 7/129 (5%)
Frame = -3
Query: 697 ILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQKISPKSQGLVRSLLHDKI 518
++ ++G G GK++ + L G +E EG + ++Y PQ+ ++ L ++L K
Sbjct: 656 LVAVVGPVGCGKSSLVSALLGEMEKLEGKVHMKG-SVAYVPQQAWIQNCTLQENVLFGKA 714
Query: 517 RDAYIHPQ------FLTDV-MKPMKIEEIMDQEVQNLSGGELQRVALVLCLGKPADVYLI 359
+ + Q L D+ M P + + ++ NLSGG+ QRV+L + AD++L+
Sbjct: 715 LNPKRYQQTLEACALLADLEMLPGGDQTEIGEKGINLSGGQRQRVSLARAVYSDADIFLL 774
Query: 358 DEPSAYLDS 332
D+P + +DS
Sbjct: 775 DDPLSAVDS 783
>M23234-1|AAA36207.1| 1279|Homo sapiens protein ( Human membrane
glycoprotein P (mdr3) mRNA, complete cds. ).
Length = 1279
Score = 50.0 bits (114), Expect = 1e-05
Identities = 66/276 (23%), Positives = 121/276 (43%), Gaps = 36/276 (13%)
Frame = -3
Query: 754 KMMGDFGLRVMPGEFSDSEILVLLGENGTGKTTFIRMLAGNLEPDEGS----GQ-LPQLH 590
K++ L+V G+ + L+G +G GK+T ++++ +PDEG+ GQ + +
Sbjct: 410 KILKGLNLKVQSGQ-----TVALVGSSGCGKSTTVQLIQRLYDPDEGTINIDGQDIRNFN 464
Query: 589 ISYKPQKISPKSQGLVR--------------SLLHDKIRDAYIHPQFLTDVMK-PMKIEE 455
++Y + I SQ V ++ D+I+ A +MK P K +
Sbjct: 465 VNYLREIIGVVSQEPVLFSTTIAENICYGRGNVTMDEIKKAVKEANAYEFIMKLPQKFDT 524
Query: 454 IMDQEVQNLSGGELQRVALVLCLGKPADVYLIDEPSAYLDSEQR------LVAAKVIKRF 293
++ + LSGG+ QR+A+ L + + L+DE ++ LD+E L A+ +
Sbjct: 525 LVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAEVQAALDKAREGRTT 584
Query: 292 ILHAKRTGFVVEHDFIMATYLADRVIVFEGTPSSNATAHAPQ-SLLNGMNKFLELLGITF 116
I+ A R V D I D VIV +G+ S L+N ++ F
Sbjct: 585 IVIAHRLSTVRNADVIAG--FEDGVIVEQGSHSELMKKEGVYFKLVNMQTSGSQIQSEEF 642
Query: 115 ---------RRDPNNFRPRINKHASVKDIEQKRAGQ 35
R PN ++ R+ +H++ K+++ + Q
Sbjct: 643 ELNDEKAATRMAPNGWKSRLFRHSTQKNLKNSQMCQ 678
Score = 45.2 bits (102), Expect = 3e-04
Identities = 50/195 (25%), Positives = 90/195 (46%), Gaps = 25/195 (12%)
Frame = -3
Query: 715 EFSDSEILVLLGENGTGKTTFIRMLAGNLEPDEGS----GQ-LPQLHISYKPQKISPKSQ 551
E + L L+G +G GK+T +++L +P G+ GQ +L++ + ++ SQ
Sbjct: 1058 EVKKGQTLALVGSSGCGKSTVVQLLERFYDPLAGTVLLDGQEAKKLNVQWLRAQLGIVSQ 1117
Query: 550 GLV----------------RSLLHDKI----RDAYIHPQFLTDVMKPMKIEEIMDQEVQN 431
+ R + D+I + A IHP F+ + P K E + +
Sbjct: 1118 EPILFDCSIAENIAYGDNSRVVSQDEIVSAAKAANIHP-FIETL--PHKYETRVGDKGTQ 1174
Query: 430 LSGGELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHD 251
LSGG+ QR+A+ L + + L+DE ++ LD+E V + + + RT V+ H
Sbjct: 1175 LSGGQKQRIAIARALIRQPQILLLDEATSALDTESEKVVQEALDK--AREGRTCIVIAHR 1232
Query: 250 FIMATYLADRVIVFE 206
+ AD ++VF+
Sbjct: 1233 -LSTIQNADLIVVFQ 1246
>EF034088-1|ABJ53424.1| 1286|Homo sapiens ATP-binding cassette,
sub-family B (MDR/TAP), member 4 protein.
Length = 1286
Score = 50.0 bits (114), Expect = 1e-05
Identities = 66/276 (23%), Positives = 121/276 (43%), Gaps = 36/276 (13%)
Frame = -3
Query: 754 KMMGDFGLRVMPGEFSDSEILVLLGENGTGKTTFIRMLAGNLEPDEGS----GQ-LPQLH 590
K++ L+V G+ + L+G +G GK+T ++++ +PDEG+ GQ + +
Sbjct: 410 KILKGLNLKVQSGQ-----TVALVGSSGCGKSTTVQLIQRLYDPDEGTINIDGQDIRNFN 464
Query: 589 ISYKPQKISPKSQGLVR--------------SLLHDKIRDAYIHPQFLTDVMK-PMKIEE 455
++Y + I SQ V ++ D+I+ A +MK P K +
Sbjct: 465 VNYLREIIGVVSQEPVLFSTTIAENICYGRGNVTMDEIKKAVKEANAYEFIMKLPQKFDT 524
Query: 454 IMDQEVQNLSGGELQRVALVLCLGKPADVYLIDEPSAYLDSEQR------LVAAKVIKRF 293
++ + LSGG+ QR+A+ L + + L+DE ++ LD+E L A+ +
Sbjct: 525 LVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAEVQAALDKAREGRTT 584
Query: 292 ILHAKRTGFVVEHDFIMATYLADRVIVFEGTPSSNATAHAPQ-SLLNGMNKFLELLGITF 116
I+ A R V D I D VIV +G+ S L+N ++ F
Sbjct: 585 IVIAHRLSTVRNADVIAG--FEDGVIVEQGSHSELMKKEGVYFKLVNMQTSGSQIQSEEF 642
Query: 115 ---------RRDPNNFRPRINKHASVKDIEQKRAGQ 35
R PN ++ R+ +H++ K+++ + Q
Sbjct: 643 ELNDEKAATRMAPNGWKSRLFRHSTQKNLKNSQMCQ 678
Score = 44.4 bits (100), Expect = 5e-04
Identities = 31/102 (30%), Positives = 52/102 (50%)
Frame = -3
Query: 511 AYIHPQFLTDVMKPMKIEEIMDQEVQNLSGGELQRVALVLCLGKPADVYLIDEPSAYLDS 332
A IHP F+ + P K E + + LSGG+ QR+A+ L + + L+DE ++ LD+
Sbjct: 1158 ANIHP-FIETL--PHKYETRVGDKGTQLSGGQKQRIAIARALIRQPQILLLDEATSALDT 1214
Query: 331 EQRLVAAKVIKRFILHAKRTGFVVEHDFIMATYLADRVIVFE 206
E V + + + RT V+ H + AD ++VF+
Sbjct: 1215 ESEKVVQEALDK--AREGRTCIVIAHR-LSTIQNADLIVVFQ 1253
>BC042531-1|AAH42531.1| 1286|Homo sapiens ATP-binding cassette,
sub-family B (MDR/TAP), member 4 protein.
Length = 1286
Score = 50.0 bits (114), Expect = 1e-05
Identities = 66/276 (23%), Positives = 121/276 (43%), Gaps = 36/276 (13%)
Frame = -3
Query: 754 KMMGDFGLRVMPGEFSDSEILVLLGENGTGKTTFIRMLAGNLEPDEGS----GQ-LPQLH 590
K++ L+V G+ + L+G +G GK+T ++++ +PDEG+ GQ + +
Sbjct: 410 KILKGLNLKVQSGQ-----TVALVGSSGCGKSTTVQLIQRLYDPDEGTINIDGQDIRNFN 464
Query: 589 ISYKPQKISPKSQGLVR--------------SLLHDKIRDAYIHPQFLTDVMK-PMKIEE 455
++Y + I SQ V ++ D+I+ A +MK P K +
Sbjct: 465 VNYLREIIGVVSQEPVLFSTTIAENICYGRGNVTMDEIKKAVKEANAYEFIMKLPQKFDT 524
Query: 454 IMDQEVQNLSGGELQRVALVLCLGKPADVYLIDEPSAYLDSEQR------LVAAKVIKRF 293
++ + LSGG+ QR+A+ L + + L+DE ++ LD+E L A+ +
Sbjct: 525 LVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAEVQAALDKAREGRTT 584
Query: 292 ILHAKRTGFVVEHDFIMATYLADRVIVFEGTPSSNATAHAPQ-SLLNGMNKFLELLGITF 116
I+ A R V D I D VIV +G+ S L+N ++ F
Sbjct: 585 IVIAHRLSTVRNADVIAG--FEDGVIVEQGSHSELMKKEGVYFKLVNMQTSGSQIQSEEF 642
Query: 115 ---------RRDPNNFRPRINKHASVKDIEQKRAGQ 35
R PN ++ R+ +H++ K+++ + Q
Sbjct: 643 ELNDEKAATRMAPNGWKSRLFRHSTQKNLKNSQMCQ 678
Score = 44.4 bits (100), Expect = 5e-04
Identities = 31/102 (30%), Positives = 52/102 (50%)
Frame = -3
Query: 511 AYIHPQFLTDVMKPMKIEEIMDQEVQNLSGGELQRVALVLCLGKPADVYLIDEPSAYLDS 332
A IHP F+ + P K E + + LSGG+ QR+A+ L + + L+DE ++ LD+
Sbjct: 1158 ANIHP-FIETL--PHKYETRVGDKGTQLSGGQKQRIAIARALIRQPQILLLDEATSALDT 1214
Query: 331 EQRLVAAKVIKRFILHAKRTGFVVEHDFIMATYLADRVIVFE 206
E V + + + RT V+ H + AD ++VF+
Sbjct: 1215 ESEKVVQEALDK--AREGRTCIVIAHR-LSTIQNADLIVVFQ 1253
>AJ294545-1|CAC69553.1| 1514|Homo sapiens multidrug resistance
associated protein protein.
Length = 1514
Score = 50.0 bits (114), Expect = 1e-05
Identities = 36/129 (27%), Positives = 68/129 (52%), Gaps = 7/129 (5%)
Frame = -3
Query: 697 ILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQKISPKSQGLVRSLLHDKI 518
++ ++G G GK++ + L G +E EG + ++Y PQ+ ++ L ++L K
Sbjct: 656 LVAVVGPVGCGKSSLVSALLGEMEKLEGKVHMKG-SVAYVPQQAWIQNCTLQENVLFGKA 714
Query: 517 RDAYIHPQ------FLTDV-MKPMKIEEIMDQEVQNLSGGELQRVALVLCLGKPADVYLI 359
+ + Q L D+ M P + + ++ NLSGG+ QRV+L + AD++L+
Sbjct: 715 LNPKRYQQTLEACALLADLEMLPGGDQTEIGEKGINLSGGQRQRVSLARAVYSDADIFLL 774
Query: 358 DEPSAYLDS 332
D+P + +DS
Sbjct: 775 DDPLSAVDS 783
>AJ275973-1|CAB93535.3| 1642|Homo sapiens ATP-binding cassette protein
protein.
Length = 1642
Score = 50.0 bits (114), Expect = 1e-05
Identities = 47/180 (26%), Positives = 76/180 (42%), Gaps = 17/180 (9%)
Frame = -3
Query: 700 EILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQKISPKSQGL---VRSLL 530
EIL LLG NG GK+T I +L G++EP G L S K G + L
Sbjct: 1327 EILGLLGPNGAGKSTIINILVGDIEPTSGQIFLGDYSSESSEDDDSLKCMGYCPQINPLW 1386
Query: 529 HD-------------KIRDAYIHPQFLTDVMKPMKIEEIMDQEVQNLSGGELQRVALVL- 392
D K A + ++ + + ++E + + V+ L G +++ L
Sbjct: 1387 PDTTLQEHFEIYGAVKGMSASDMKEVISRITHALDLKEHLQKTVKKLPAGIKRKLCFALS 1446
Query: 391 CLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMATYLADRVIV 212
LG P + L+DEPS +D + + + I+ + KR + H A + DRV +
Sbjct: 1447 MLGNP-QITLLDEPSTGMDPKAKQHMWRAIRTAFKNRKRAAILTTHYMEEAEAVCDRVAI 1505
Score = 49.2 bits (112), Expect = 2e-05
Identities = 48/192 (25%), Positives = 84/192 (43%), Gaps = 18/192 (9%)
Frame = -3
Query: 733 LRVMPGEFSDSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQKISPKS 554
LR + + + +I LLG +GTGK+T + +L G P +G + +S + +
Sbjct: 497 LRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDEMFEARK 556
Query: 553 Q-GLVRSL-LHDKIRDAYIHPQFLTD---------------VMKPMKIEEIMDQEVQNLS 425
G+ L +H + + L V+ + ++ I D + + LS
Sbjct: 557 MIGICPQLDIHFDVLTVEENLSILASIKGIPANNIIQEVQKVLLDLDMQTIKDNQAKKLS 616
Query: 424 GGELQRVAL-VLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDF 248
GG+ ++++L + LG P + L+DEP+A +D R + ++K A R H
Sbjct: 617 GGQKRKLSLGIAVLGNPK-ILLLDEPTAGMDPCSRHIVWNLLK--YRKANRVTVFSTHFM 673
Query: 247 IMATYLADRVIV 212
A LADR V
Sbjct: 674 DEADILADRKAV 685
>AF104943-1|AAD04170.1| 1527|Homo sapiens ABC transporter MOAT-D
protein.
Length = 1527
Score = 50.0 bits (114), Expect = 1e-05
Identities = 36/129 (27%), Positives = 68/129 (52%), Gaps = 7/129 (5%)
Frame = -3
Query: 697 ILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQKISPKSQGLVRSLLHDKI 518
++ ++G G GK++ + L G +E EG + ++Y PQ+ ++ L ++L K
Sbjct: 656 LVAVVGPVGCGKSSLVSALLGEMEKLEGKVHMKG-SVAYVPQQAWIQNCTLQENVLFGKA 714
Query: 517 RDAYIHPQ------FLTDV-MKPMKIEEIMDQEVQNLSGGELQRVALVLCLGKPADVYLI 359
+ + Q L D+ M P + + ++ NLSGG+ QRV+L + AD++L+
Sbjct: 715 LNPKRYQQTLEACALLADLEMLPGGDQTEIGEKGINLSGGQRQRVSLARAVYSDADIFLL 774
Query: 358 DEPSAYLDS 332
D+P + +DS
Sbjct: 775 DDPLSAVDS 783
>AF085691-1|AAD02846.1| 1238|Homo sapiens multidrug
resistance-associated protein 3A protein.
Length = 1238
Score = 50.0 bits (114), Expect = 1e-05
Identities = 36/129 (27%), Positives = 68/129 (52%), Gaps = 7/129 (5%)
Frame = -3
Query: 697 ILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQKISPKSQGLVRSLLHDKI 518
++ ++G G GK++ + L G +E EG + ++Y PQ+ ++ L ++L K
Sbjct: 656 LVAVVGPVGCGKSSLVSALLGEMEKLEGKVHMKG-SVAYVPQQAWIQNCTLQENVLFGKA 714
Query: 517 RDAYIHPQ------FLTDV-MKPMKIEEIMDQEVQNLSGGELQRVALVLCLGKPADVYLI 359
+ + Q L D+ M P + + ++ NLSGG+ QRV+L + AD++L+
Sbjct: 715 LNPKRYQQTLEACALLADLEMLPGGDQTEIGEKGINLSGGQRQRVSLARAVYSDADIFLL 774
Query: 358 DEPSAYLDS 332
D+P + +DS
Sbjct: 775 DDPLSAVDS 783
>AF085690-1|AAD02845.1| 1527|Homo sapiens multidrug
resistance-associated protein 3 protein.
Length = 1527
Score = 50.0 bits (114), Expect = 1e-05
Identities = 36/129 (27%), Positives = 68/129 (52%), Gaps = 7/129 (5%)
Frame = -3
Query: 697 ILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQKISPKSQGLVRSLLHDKI 518
++ ++G G GK++ + L G +E EG + ++Y PQ+ ++ L ++L K
Sbjct: 656 LVAVVGPVGCGKSSLVSALLGEMEKLEGKVHMKG-SVAYVPQQAWIQNCTLQENVLFGKA 714
Query: 517 RDAYIHPQ------FLTDV-MKPMKIEEIMDQEVQNLSGGELQRVALVLCLGKPADVYLI 359
+ + Q L D+ M P + + ++ NLSGG+ QRV+L + AD++L+
Sbjct: 715 LNPKRYQQTLEACALLADLEMLPGGDQTEIGEKGINLSGGQRQRVSLARAVYSDADIFLL 774
Query: 358 DEPSAYLDS 332
D+P + +DS
Sbjct: 775 DDPLSAVDS 783
>AF083552-1|AAC34668.1| 1527|Homo sapiens canalicular multispecific
organic anion transporter 2 protein.
Length = 1527
Score = 50.0 bits (114), Expect = 1e-05
Identities = 36/129 (27%), Positives = 68/129 (52%), Gaps = 7/129 (5%)
Frame = -3
Query: 697 ILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQKISPKSQGLVRSLLHDKI 518
++ ++G G GK++ + L G +E EG + ++Y PQ+ ++ L ++L K
Sbjct: 656 LVAVVGPVGCGKSSLVSALLGEMEKLEGKVHMKG-SVAYVPQQAWIQNCTLQENVLFGKA 714
Query: 517 RDAYIHPQ------FLTDV-MKPMKIEEIMDQEVQNLSGGELQRVALVLCLGKPADVYLI 359
+ + Q L D+ M P + + ++ NLSGG+ QRV+L + AD++L+
Sbjct: 715 LNPKRYQQTLEACALLADLEMLPGGDQTEIGEKGINLSGGQRQRVSLARAVYSDADIFLL 774
Query: 358 DEPSAYLDS 332
D+P + +DS
Sbjct: 775 DDPLSAVDS 783
>AF009670-1|AAD01430.1| 1528|Homo sapiens MRP3 protein.
Length = 1528
Score = 50.0 bits (114), Expect = 1e-05
Identities = 36/129 (27%), Positives = 68/129 (52%), Gaps = 7/129 (5%)
Frame = -3
Query: 697 ILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQKISPKSQGLVRSLLHDKI 518
++ ++G G GK++ + L G +E EG + ++Y PQ+ ++ L ++L K
Sbjct: 657 LVAVVGPVGCGKSSLVSALLGEMEKLEGKVHMKG-SVAYVPQQAWIQNCTLQENVLFGKA 715
Query: 517 RDAYIHPQ------FLTDV-MKPMKIEEIMDQEVQNLSGGELQRVALVLCLGKPADVYLI 359
+ + Q L D+ M P + + ++ NLSGG+ QRV+L + AD++L+
Sbjct: 716 LNPKRYQQTLEACALLADLEMLPGGDQTEIGEKGINLSGGQRQRVSLARAVYSDADIFLL 775
Query: 358 DEPSAYLDS 332
D+P + +DS
Sbjct: 776 DDPLSAVDS 784
>AB208954-1|BAD92191.1| 1533|Homo sapiens ATP-binding cassette,
sub-family C, member 3 isoform MRP3 variant protein.
Length = 1533
Score = 50.0 bits (114), Expect = 1e-05
Identities = 36/129 (27%), Positives = 68/129 (52%), Gaps = 7/129 (5%)
Frame = -3
Query: 697 ILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQKISPKSQGLVRSLLHDKI 518
++ ++G G GK++ + L G +E EG + ++Y PQ+ ++ L ++L K
Sbjct: 662 LVAVVGPVGCGKSSLVSALLGEMEKLEGKVHMKG-SVAYVPQQAWIQNCTLQENVLFGKA 720
Query: 517 RDAYIHPQ------FLTDV-MKPMKIEEIMDQEVQNLSGGELQRVALVLCLGKPADVYLI 359
+ + Q L D+ M P + + ++ NLSGG+ QRV+L + AD++L+
Sbjct: 721 LNPKRYQQTLEACALLADLEMLPGGDQTEIGEKGINLSGGQRQRVSLARAVYSDADIFLL 780
Query: 358 DEPSAYLDS 332
D+P + +DS
Sbjct: 781 DDPLSAVDS 789
>AB010887-1|BAA28146.1| 1527|Homo sapiens multidrug
resistance-associated protein(MRP)-like protein-2 (MLP-2)
protein.
Length = 1527
Score = 50.0 bits (114), Expect = 1e-05
Identities = 36/129 (27%), Positives = 68/129 (52%), Gaps = 7/129 (5%)
Frame = -3
Query: 697 ILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQKISPKSQGLVRSLLHDKI 518
++ ++G G GK++ + L G +E EG + ++Y PQ+ ++ L ++L K
Sbjct: 656 LVAVVGPVGCGKSSLVSALLGEMEKLEGKVHMKG-SVAYVPQQAWIQNCTLQENVLFGKA 714
Query: 517 RDAYIHPQ------FLTDV-MKPMKIEEIMDQEVQNLSGGELQRVALVLCLGKPADVYLI 359
+ + Q L D+ M P + + ++ NLSGG+ QRV+L + AD++L+
Sbjct: 715 LNPKRYQQTLEACALLADLEMLPGGDQTEIGEKGINLSGGQRQRVSLARAVYSDADIFLL 774
Query: 358 DEPSAYLDS 332
D+P + +DS
Sbjct: 775 DDPLSAVDS 783
>BC051320-1|AAH51320.1| 419|Homo sapiens ABCA10 protein protein.
Length = 419
Score = 49.6 bits (113), Expect = 1e-05
Identities = 50/186 (26%), Positives = 89/186 (47%), Gaps = 19/186 (10%)
Frame = -3
Query: 700 EILVLLGENGTGKTTFIRMLAGNLEPDEG-------SGQLPQLH------ISYKPQKIS- 563
E+L LLG NG GK+T I+M+ G +P G + Q H + Y PQ+ S
Sbjct: 109 EVLGLLGHNGAGKSTSIKMITGCTKPTAGVVVLQGSRASVRQQHDNSLKFLGYCPQENSL 168
Query: 562 -PKSQGLVRSLLHDKIRDAYIHPQFL--TDVMKPMKIEEIMDQEVQNLSGGELQRVALVL 392
PK L+ ++ L + +++ +K++E + V+ LS G +++ VL
Sbjct: 169 WPKLTMKEHLELYAAVKGLGKEDAALSISRLVEALKLQEQLKAPVKTLSEGIKRKLCFVL 228
Query: 391 -CLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMATYLADRV- 218
LG P+ V L+DEP +D E + ++++ + + +R + H A + DR+
Sbjct: 229 SILGNPS-VVLLDEPFTGMDPEGQQQMWQILQATVKNKERGTLLTTHYMSEAEAVCDRMA 287
Query: 217 IVFEGT 200
++ GT
Sbjct: 288 MMVSGT 293
>AY247105-1|AAO72160.1| 1543|Homo sapiens ATP-binding cassette
sub-family A member 10 protein.
Length = 1543
Score = 49.6 bits (113), Expect = 1e-05
Identities = 50/186 (26%), Positives = 89/186 (47%), Gaps = 19/186 (10%)
Frame = -3
Query: 700 EILVLLGENGTGKTTFIRMLAGNLEPDEG-------SGQLPQLH------ISYKPQKIS- 563
E+L LLG NG GK+T I+M+ G +P G + Q H + Y PQ+ S
Sbjct: 1233 EVLGLLGHNGAGKSTSIKMITGCTKPTAGVVVLQGSRASVRQQHDNSLKFLGYCPQENSL 1292
Query: 562 -PKSQGLVRSLLHDKIRDAYIHPQFL--TDVMKPMKIEEIMDQEVQNLSGGELQRVALVL 392
PK L+ ++ L + +++ +K++E + V+ LS G +++ VL
Sbjct: 1293 WPKLTMKEHLELYAAVKGLGKEDAALSISRLVEALKLQEQLKAPVKTLSEGIKRKLCFVL 1352
Query: 391 -CLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMATYLADRV- 218
LG P+ V L+DEP +D E + ++++ + + +R + H A + DR+
Sbjct: 1353 SILGNPS-VVLLDEPFTGMDPEGQQQMWQILQATVKNKERGTLLTTHYMSEAEAVCDRMA 1411
Query: 217 IVFEGT 200
++ GT
Sbjct: 1412 MMVSGT 1417
Score = 44.4 bits (100), Expect = 5e-04
Identities = 51/177 (28%), Positives = 82/177 (46%), Gaps = 23/177 (12%)
Frame = -3
Query: 706 DSEILVLLGENGTGKTTFIRMLAGNLEPDEGSG-----QLPQL--------HISYKPQKI 566
+ +I +LG NG GK+T + +L+G EGS QL ++ +I + PQ
Sbjct: 419 EGQITAILGHNGAGKSTLLNILSGLSVSTEGSATIYNTQLSEITDMEEIRKNIGFCPQFN 478
Query: 565 SPKSQGLVRSLLHDKIRDAYIHP----QFLTDVMKPMKIEEIMDQEVQNLSGGELQRVAL 398
VR L + I P Q + ++ + ++ I D + LSGG+ +++ L
Sbjct: 479 FQFDFLTVRENLRVFAKIKGIQPKEVEQEVKRIIMELDMQSIQDIIAKKLSGGQKRKLTL 538
Query: 397 -VLCLGKPADVYLIDEPSAYLDSEQR-----LVAAKVIKRFILHAKRTGFVVEHDFI 245
+ LG P V L+DEP+A LD R L+ + R IL + T F+ E D +
Sbjct: 539 GIAILGDP-QVLLLDEPTAGLDPFSRHRVWSLLKEHKVDRLILFS--TQFMDEADIL 592
>AY247065-1|AAO72161.1| 1543|Homo sapiens ATP-binding cassette
sub-family A member 10 protein.
Length = 1543
Score = 49.6 bits (113), Expect = 1e-05
Identities = 50/186 (26%), Positives = 89/186 (47%), Gaps = 19/186 (10%)
Frame = -3
Query: 700 EILVLLGENGTGKTTFIRMLAGNLEPDEG-------SGQLPQLH------ISYKPQKIS- 563
E+L LLG NG GK+T I+M+ G +P G + Q H + Y PQ+ S
Sbjct: 1233 EVLGLLGHNGAGKSTSIKMITGCTKPTAGVVVLQGSRASVRQQHDNSLKFLGYCPQENSL 1292
Query: 562 -PKSQGLVRSLLHDKIRDAYIHPQFL--TDVMKPMKIEEIMDQEVQNLSGGELQRVALVL 392
PK L+ ++ L + +++ +K++E + V+ LS G +++ VL
Sbjct: 1293 WPKLTMKEHLELYAAVKGLGKEDAALSISRLVEALKLQEQLKAPVKTLSEGIKRKLCFVL 1352
Query: 391 -CLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMATYLADRV- 218
LG P+ V L+DEP +D E + ++++ + + +R + H A + DR+
Sbjct: 1353 SILGNPS-VVLLDEPFTGMDPEGQQQMWQILQATVKNKERGTLLTTHYMSEAEAVCDRMA 1411
Query: 217 IVFEGT 200
++ GT
Sbjct: 1412 MMVSGT 1417
Score = 44.4 bits (100), Expect = 5e-04
Identities = 51/177 (28%), Positives = 82/177 (46%), Gaps = 23/177 (12%)
Frame = -3
Query: 706 DSEILVLLGENGTGKTTFIRMLAGNLEPDEGSG-----QLPQL--------HISYKPQKI 566
+ +I +LG NG GK+T + +L+G EGS QL ++ +I + PQ
Sbjct: 419 EGQITAILGHNGAGKSTLLNILSGLSVSTEGSATIYNTQLSEITDMEEIRKNIGFCPQFN 478
Query: 565 SPKSQGLVRSLLHDKIRDAYIHP----QFLTDVMKPMKIEEIMDQEVQNLSGGELQRVAL 398
VR L + I P Q + ++ + ++ I D + LSGG+ +++ L
Sbjct: 479 FQFDFLTVRENLRVFAKIKGIQPKEVEQEVKRIIMELDMQSIQDIIAKKLSGGQKRKLTL 538
Query: 397 -VLCLGKPADVYLIDEPSAYLDSEQR-----LVAAKVIKRFILHAKRTGFVVEHDFI 245
+ LG P V L+DEP+A LD R L+ + R IL + T F+ E D +
Sbjct: 539 GIAILGDP-QVLLLDEPTAGLDPFSRHRVWSLLKEHKVDRLILFS--TQFMDEADIL 592
>AY028900-1|AAK30025.1| 1543|Homo sapiens ATP-binding cassette A10
protein.
Length = 1543
Score = 49.6 bits (113), Expect = 1e-05
Identities = 50/186 (26%), Positives = 89/186 (47%), Gaps = 19/186 (10%)
Frame = -3
Query: 700 EILVLLGENGTGKTTFIRMLAGNLEPDEG-------SGQLPQLH------ISYKPQKIS- 563
E+L LLG NG GK+T I+M+ G +P G + Q H + Y PQ+ S
Sbjct: 1233 EVLGLLGHNGAGKSTSIKMITGCTKPTAGVVVLQGSRASVRQQHDNSLKFLGYCPQENSL 1292
Query: 562 -PKSQGLVRSLLHDKIRDAYIHPQFL--TDVMKPMKIEEIMDQEVQNLSGGELQRVALVL 392
PK L+ ++ L + +++ +K++E + V+ LS G +++ VL
Sbjct: 1293 WPKLTMKEHLELYAAVKGLGKEDAALSISRLVEALKLQEQLKAPVKTLSEGIKRKLCFVL 1352
Query: 391 -CLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMATYLADRV- 218
LG P+ V L+DEP +D E + ++++ + + +R + H A + DR+
Sbjct: 1353 SILGNPS-VVLLDEPFTGMDPEGQQQMWQILQATVKNKERGTLLTTHYMSEAEAVCDRMA 1411
Query: 217 IVFEGT 200
++ GT
Sbjct: 1412 MMVSGT 1417
Score = 44.4 bits (100), Expect = 5e-04
Identities = 51/177 (28%), Positives = 82/177 (46%), Gaps = 23/177 (12%)
Frame = -3
Query: 706 DSEILVLLGENGTGKTTFIRMLAGNLEPDEGSG-----QLPQL--------HISYKPQKI 566
+ +I +LG NG GK+T + +L+G EGS QL ++ +I + PQ
Sbjct: 419 EGQITAILGHNGAGKSTLLNILSGLSVSTEGSATIYNTQLSEITDMEEIRKNIGFCPQFN 478
Query: 565 SPKSQGLVRSLLHDKIRDAYIHP----QFLTDVMKPMKIEEIMDQEVQNLSGGELQRVAL 398
VR L + I P Q + ++ + ++ I D + LSGG+ +++ L
Sbjct: 479 FQFDFLTVRENLRVFAKIKGIQPKEVEQEVKRIIMELDMQSIQDIIAKKLSGGQKRKLTL 538
Query: 397 -VLCLGKPADVYLIDEPSAYLDSEQR-----LVAAKVIKRFILHAKRTGFVVEHDFI 245
+ LG P V L+DEP+A LD R L+ + R IL + T F+ E D +
Sbjct: 539 GIAILGDP-QVLLLDEPTAGLDPFSRHRVWSLLKEHKVDRLILFS--TQFMDEADIL 592
>AK056533-1|BAB71208.1| 865|Homo sapiens protein ( Homo sapiens cDNA
FLJ31971 fis, clone NT2RP7008137, weakly similar to
ATP-BINDING CASSETTE, SUB-FAMILY A, MEMBER 1. ).
Length = 865
Score = 49.6 bits (113), Expect = 1e-05
Identities = 47/180 (26%), Positives = 76/180 (42%), Gaps = 17/180 (9%)
Frame = -3
Query: 700 EILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQKISPKSQGL---VRSLL 530
EIL LLG NG GK+T I +L G++EP G L S K G + L
Sbjct: 550 EILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYSSETSEDDGSLKCMGYCPQINPLW 609
Query: 529 HD-------------KIRDAYIHPQFLTDVMKPMKIEEIMDQEVQNLSGGELQRVALVL- 392
D K A + ++ + + ++E + + V+ L G +++ L
Sbjct: 610 PDTTLQEHFEIYGAVKGMSASDMKEVISRITHGLDLKEHLQKTVKKLPAGIKRKLCFALS 669
Query: 391 CLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMATYLADRVIV 212
LG P + L+DEPS +D + + + I+ + KR + H A + DRV +
Sbjct: 670 MLGNP-QITLLDEPSTGMDPKAKQHMWRAIRTAFKNRKRAAILTTHYMEEAEAVCDRVAI 728
>BX640746-1|CAE45856.1| 431|Homo sapiens hypothetical protein
protein.
Length = 431
Score = 49.2 bits (112), Expect = 2e-05
Identities = 48/192 (25%), Positives = 84/192 (43%), Gaps = 18/192 (9%)
Frame = -3
Query: 733 LRVMPGEFSDSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQKISPKS 554
LR + + + +I LLG +GTGK+T + +L G P +G + +S + +
Sbjct: 168 LRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDEMFEARK 227
Query: 553 Q-GLVRSL-LHDKIRDAYIHPQFLTD---------------VMKPMKIEEIMDQEVQNLS 425
G+ L +H + + L V+ + ++ I D + + LS
Sbjct: 228 MIGICPQLDIHFDVLTVEENLSILASIKGIPANNIIQEVQKVLLDLDMQTIKDNQAKKLS 287
Query: 424 GGELQRVAL-VLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDF 248
GG+ ++++L + LG P + L+DEP+A +D R + ++K A R H
Sbjct: 288 GGQKRKLSLGIAVLGNPK-ILLLDEPTAGMDPCSRHIVWNLLK--YRKANRVTVFSTHFM 344
Query: 247 IMATYLADRVIV 212
A LADR V
Sbjct: 345 DEADILADRKAV 356
>AJ512612-1|CAD54757.1| 925|Homo sapiens ABCA5 transporter protein.
Length = 925
Score = 49.2 bits (112), Expect = 2e-05
Identities = 48/192 (25%), Positives = 84/192 (43%), Gaps = 18/192 (9%)
Frame = -3
Query: 733 LRVMPGEFSDSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQKISPKS 554
LR + + + +I LLG +GTGK+T + +L G P +G + +S + +
Sbjct: 497 LRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDEMFEARK 556
Query: 553 Q-GLVRSL-LHDKIRDAYIHPQFLTD---------------VMKPMKIEEIMDQEVQNLS 425
G+ L +H + + L V+ + ++ I D + + LS
Sbjct: 557 MIGICPQLDIHFDVLTVEENLSILASIKGIPANNIIQEVQKVLLDLDMQTIKDNQAKKLS 616
Query: 424 GGELQRVAL-VLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDF 248
GG+ ++++L + LG P + L+DEP+A +D R + ++K A R H
Sbjct: 617 GGQKRKLSLGIAVLGNPK-ILLLDEPTAGMDPCSRHIVWNLLK--YRKANRVTVFSTHFM 673
Query: 247 IMATYLADRVIV 212
A LADR V
Sbjct: 674 DEADILADRKAV 685
>U91318-3|AAC15785.1| 848|Homo sapiens Gene product with similarity
to Multidrug resistance protein MRP1 protein.
Length = 848
Score = 48.4 bits (110), Expect = 3e-05
Identities = 37/129 (28%), Positives = 65/129 (50%), Gaps = 7/129 (5%)
Frame = -3
Query: 697 ILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQKISPKSQGLVRSLLHDKI 518
+L ++G G GK++ + L G L EG + ++Y PQ+ ++ +V ++ +
Sbjct: 616 LLAVVGPVGAGKSSLLSALLGELSKVEGFVSIEGA-VAYVPQEAWVQNTSVVENVCFGQE 674
Query: 517 RDAYIHPQFLT------DVMK-PMKIEEIMDQEVQNLSGGELQRVALVLCLGKPADVYLI 359
D + L DV P I + ++ NLSGG+ QR++L + + A VYL+
Sbjct: 675 LDPPWLERVLEACALQPDVDSFPEGIHTSIGEQGMNLSGGQKQRLSLARAVYRKAAVYLL 734
Query: 358 DEPSAYLDS 332
D+P A LD+
Sbjct: 735 DDPLAALDA 743
>L05628-1|AAB46616.1| 1531|Homo sapiens multidrug
resistance-associated protein protein.
Length = 1531
Score = 48.4 bits (110), Expect = 3e-05
Identities = 52/204 (25%), Positives = 96/204 (47%), Gaps = 11/204 (5%)
Frame = -3
Query: 706 DSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQKISPKSQGLVRSLLH 527
+ ++ ++G+ G GK++ + L ++ EG + ++Y PQ+ ++ L ++L
Sbjct: 670 EGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVAIKG-SVAYVPQQAWIQNDSLRENILF 728
Query: 526 D-KIRDAYIHPQFLTDVMKP-MKI------EEIMDQEVQNLSGGELQRVALVLCLGKPAD 371
++ + Y + P ++I EI ++ V NLSGG+ QRV+L + AD
Sbjct: 729 GCQLEEPYYRSVIQACALLPDLEILPSGDRTEIGEKGV-NLSGGQKQRVSLARAVYSNAD 787
Query: 370 VYLIDEPSAYLDSE-QRLVAAKVIKRFILHAKRTGFVVEHDFIMATYL--ADRVIVFEGT 200
+YL D+P + +D+ + + VI + +T +V H +YL D +IV G
Sbjct: 788 IYLFDDPLSAVDAHVGKHIFENVIGPKGMLKNKTRILVTHSM---SYLPQVDVIIVMSGG 844
Query: 199 PSSNATAHAPQSLLNGMNKFLELL 128
S ++ Q LL F E L
Sbjct: 845 KISEMGSY--QELLARDGAFAEFL 866
>EF419769-1|ABN79590.1| 1531|Homo sapiens ATP-binding cassette,
sub-family C (CFTR/MRP), member 1 protein.
Length = 1531
Score = 48.4 bits (110), Expect = 3e-05
Identities = 52/204 (25%), Positives = 96/204 (47%), Gaps = 11/204 (5%)
Frame = -3
Query: 706 DSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQKISPKSQGLVRSLLH 527
+ ++ ++G+ G GK++ + L ++ EG + ++Y PQ+ ++ L ++L
Sbjct: 670 EGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVAIKG-SVAYVPQQAWIQNDSLRENILF 728
Query: 526 D-KIRDAYIHPQFLTDVMKP-MKI------EEIMDQEVQNLSGGELQRVALVLCLGKPAD 371
++ + Y + P ++I EI ++ V NLSGG+ QRV+L + AD
Sbjct: 729 GCQLEEPYYRSVIQACALLPDLEILPSGDRTEIGEKGV-NLSGGQKQRVSLARAVYSNAD 787
Query: 370 VYLIDEPSAYLDSE-QRLVAAKVIKRFILHAKRTGFVVEHDFIMATYL--ADRVIVFEGT 200
+YL D+P + +D+ + + VI + +T +V H +YL D +IV G
Sbjct: 788 IYLFDDPLSAVDAHVGKHIFENVIGPKGMLKNKTRILVTHSM---SYLPQVDVIIVMSGG 844
Query: 199 PSSNATAHAPQSLLNGMNKFLELL 128
S ++ Q LL F E L
Sbjct: 845 KISEMGSY--QELLARDGAFAEFL 866
>BC131732-1|AAI31733.1| 1503|Homo sapiens ATP-binding cassette,
sub-family C (CFTR/MRP), member 6 protein.
Length = 1503
Score = 48.4 bits (110), Expect = 3e-05
Identities = 37/129 (28%), Positives = 65/129 (50%), Gaps = 7/129 (5%)
Frame = -3
Query: 697 ILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQKISPKSQGLVRSLLHDKI 518
+L ++G G GK++ + L G L EG + ++Y PQ+ ++ +V ++ +
Sbjct: 658 LLAVVGPVGAGKSSLLSALLGELSKVEGFVSIEGA-VAYVPQEAWVQNTSVVENVCFGQE 716
Query: 517 RDAYIHPQFLT------DVMK-PMKIEEIMDQEVQNLSGGELQRVALVLCLGKPADVYLI 359
D + L DV P I + ++ NLSGG+ QR++L + + A VYL+
Sbjct: 717 LDPPWLERVLEACALQPDVDSFPEGIHTSIGEQGMNLSGGQKQRLSLARAVYRKAAVYLL 776
Query: 358 DEPSAYLDS 332
D+P A LD+
Sbjct: 777 DDPLAALDA 785
>AF168791-1|AAD51293.1| 1503|Homo sapiens multi-specific organic anion
tranporter-E protein.
Length = 1503
Score = 48.4 bits (110), Expect = 3e-05
Identities = 37/129 (28%), Positives = 65/129 (50%), Gaps = 7/129 (5%)
Frame = -3
Query: 697 ILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQKISPKSQGLVRSLLHDKI 518
+L ++G G GK++ + L G L EG + ++Y PQ+ ++ +V ++ +
Sbjct: 658 LLAVVGPVGAGKSSLLSALLGELSKVEGFVSIEGA-VAYVPQEAWVQNTSVVENVCFGQE 716
Query: 517 RDAYIHPQFLT------DVMK-PMKIEEIMDQEVQNLSGGELQRVALVLCLGKPADVYLI 359
D + L DV P I + ++ NLSGG+ QR++L + + A VYL+
Sbjct: 717 LDPPWLERVLEACALQPDVDSFPEGIHTSIGEQGMNLSGGQKQRLSLARAVYRKAAVYLL 776
Query: 358 DEPSAYLDS 332
D+P A LD+
Sbjct: 777 DDPLAALDA 785
>AF076622-1|AAC79696.1| 1503|Homo sapiens MRP6 protein.
Length = 1503
Score = 48.4 bits (110), Expect = 3e-05
Identities = 37/129 (28%), Positives = 65/129 (50%), Gaps = 7/129 (5%)
Frame = -3
Query: 697 ILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQKISPKSQGLVRSLLHDKI 518
+L ++G G GK++ + L G L EG + ++Y PQ+ ++ +V ++ +
Sbjct: 658 LLAVVGPVGAGKSSLLSALLGELSKVEGFVSIEGA-VAYVPQEAWVQNTSVVENVCFGQE 716
Query: 517 RDAYIHPQFLT------DVMK-PMKIEEIMDQEVQNLSGGELQRVALVLCLGKPADVYLI 359
D + L DV P I + ++ NLSGG+ QR++L + + A VYL+
Sbjct: 717 LDPPWLERVLEACALQPDVDSFPEGIHTSIGEQGMNLSGGQKQRLSLARAVYRKAAVYLL 776
Query: 358 DEPSAYLDS 332
D+P A LD+
Sbjct: 777 DDPLAALDA 785
>AF022853-2|AAB83983.1| 1450|Homo sapiens multidrug resistance protein
protein.
Length = 1450
Score = 48.4 bits (110), Expect = 3e-05
Identities = 52/204 (25%), Positives = 96/204 (47%), Gaps = 11/204 (5%)
Frame = -3
Query: 706 DSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQKISPKSQGLVRSLLH 527
+ ++ ++G+ G GK++ + L ++ EG + ++Y PQ+ ++ L ++L
Sbjct: 654 EGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVAIKG-SVAYVPQQAWIQNDSLRENILF 712
Query: 526 D-KIRDAYIHPQFLTDVMKP-MKI------EEIMDQEVQNLSGGELQRVALVLCLGKPAD 371
++ + Y + P ++I EI ++ V NLSGG+ QRV+L + AD
Sbjct: 713 GCQLEEPYYRSVIQACALLPDLEILPSGDRTEIGEKGV-NLSGGQKQRVSLARAVYSNAD 771
Query: 370 VYLIDEPSAYLDSE-QRLVAAKVIKRFILHAKRTGFVVEHDFIMATYL--ADRVIVFEGT 200
+YL D+P + +D+ + + VI + +T +V H +YL D +IV G
Sbjct: 772 IYLFDDPLSAVDAHVGKHIFENVIGPKGMLKNKTRILVTHSM---SYLPQVDVIIVMSGG 828
Query: 199 PSSNATAHAPQSLLNGMNKFLELL 128
S ++ Q LL F E L
Sbjct: 829 KISEMGSY--QELLARDGAFAEFL 850
>AF022853-1|AAB83979.1| 1515|Homo sapiens multidrug resistance protein
protein.
Length = 1515
Score = 48.4 bits (110), Expect = 3e-05
Identities = 52/204 (25%), Positives = 96/204 (47%), Gaps = 11/204 (5%)
Frame = -3
Query: 706 DSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQKISPKSQGLVRSLLH 527
+ ++ ++G+ G GK++ + L ++ EG + ++Y PQ+ ++ L ++L
Sbjct: 654 EGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVAIKG-SVAYVPQQAWIQNDSLRENILF 712
Query: 526 D-KIRDAYIHPQFLTDVMKP-MKI------EEIMDQEVQNLSGGELQRVALVLCLGKPAD 371
++ + Y + P ++I EI ++ V NLSGG+ QRV+L + AD
Sbjct: 713 GCQLEEPYYRSVIQACALLPDLEILPSGDRTEIGEKGV-NLSGGQKQRVSLARAVYSNAD 771
Query: 370 VYLIDEPSAYLDSE-QRLVAAKVIKRFILHAKRTGFVVEHDFIMATYL--ADRVIVFEGT 200
+YL D+P + +D+ + + VI + +T +V H +YL D +IV G
Sbjct: 772 IYLFDDPLSAVDAHVGKHIFENVIGPKGMLKNKTRILVTHSM---SYLPQVDVIIVMSGG 828
Query: 199 PSSNATAHAPQSLLNGMNKFLELL 128
S ++ Q LL F E L
Sbjct: 829 KISEMGSY--QELLARDGAFAEFL 850
>AC003026-1|AAC05808.1| 691|Homo sapiens Multiple drug resistance
gene MRP1 (partial) protein.
Length = 691
Score = 48.4 bits (110), Expect = 3e-05
Identities = 52/204 (25%), Positives = 96/204 (47%), Gaps = 11/204 (5%)
Frame = -3
Query: 706 DSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQKISPKSQGLVRSLLH 527
+ ++ ++G+ G GK++ + L ++ EG + ++Y PQ+ ++ L ++L
Sbjct: 155 EGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVAIKG-SVAYVPQQAWIQNDSLRENILF 213
Query: 526 D-KIRDAYIHPQFLTDVMKP-MKI------EEIMDQEVQNLSGGELQRVALVLCLGKPAD 371
++ + Y + P ++I EI ++ V NLSGG+ QRV+L + AD
Sbjct: 214 GCQLEEPYYRSVIQACALLPDLEILPSGDRTEIGEKGV-NLSGGQKQRVSLARAVYSNAD 272
Query: 370 VYLIDEPSAYLDSE-QRLVAAKVIKRFILHAKRTGFVVEHDFIMATYL--ADRVIVFEGT 200
+YL D+P + +D+ + + VI + +T +V H +YL D +IV G
Sbjct: 273 IYLFDDPLSAVDAHVGKHIFENVIGPKGMLKNKTRILVTHSM---SYLPQVDVIIVMSGG 329
Query: 199 PSSNATAHAPQSLLNGMNKFLELL 128
S ++ Q LL F E L
Sbjct: 330 KISEMGSY--QELLARDGAFAEFL 351
>AB209120-1|BAD92357.1| 1439|Homo sapiens ATP-binding cassette,
sub-family C, member 1 isoform 1 variant protein.
Length = 1439
Score = 48.4 bits (110), Expect = 3e-05
Identities = 52/204 (25%), Positives = 96/204 (47%), Gaps = 11/204 (5%)
Frame = -3
Query: 706 DSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQKISPKSQGLVRSLLH 527
+ ++ ++G+ G GK++ + L ++ EG + ++Y PQ+ ++ L ++L
Sbjct: 568 EGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVAIKG-SVAYVPQQAWIQNDSLRENILF 626
Query: 526 D-KIRDAYIHPQFLTDVMKP-MKI------EEIMDQEVQNLSGGELQRVALVLCLGKPAD 371
++ + Y + P ++I EI ++ V NLSGG+ QRV+L + AD
Sbjct: 627 GCQLEEPYYRSVIQACALLPDLEILPSGDRTEIGEKGV-NLSGGQKQRVSLARAVYSNAD 685
Query: 370 VYLIDEPSAYLDSE-QRLVAAKVIKRFILHAKRTGFVVEHDFIMATYL--ADRVIVFEGT 200
+YL D+P + +D+ + + VI + +T +V H +YL D +IV G
Sbjct: 686 IYLFDDPLSAVDAHVGKHIFENVIGPKGMLKNKTRILVTHSM---SYLPQVDVIIVMSGG 742
Query: 199 PSSNATAHAPQSLLNGMNKFLELL 128
S ++ Q LL F E L
Sbjct: 743 KISEMGSY--QELLARDGAFAEFL 764
>BC043423-1|AAH43423.1| 301|Homo sapiens ABCB6 protein protein.
Length = 301
Score = 47.2 bits (107), Expect = 7e-05
Identities = 55/209 (26%), Positives = 90/209 (43%), Gaps = 21/209 (10%)
Frame = -3
Query: 769 YPEMXKMMGDFGLRVMPGEFSDSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLH 590
Y + + + D VMPG+ L L+G +G GK+T +R+L + G ++
Sbjct: 58 YADGRETLQDVSFTVMPGQ-----TLALVGPSGAGKSTILRLLFRFYDISSGCIRIDGQD 112
Query: 589 ISYKPQK-------ISPKSQGLVRSLLHDKIR-----------DAYIHPQFLTDVMK--P 470
IS Q + P+ L + D IR +A + D + P
Sbjct: 113 ISQVTQASLRSHIGVVPQDTVLFNDTIADNIRYGRVTAGNDEVEAAAQAAGIHDAIMAFP 172
Query: 469 MKIEEIMDQEVQNLSGGELQRVALVLCLGKPADVYLIDEPSAYLD-SEQRLVAAKVIKRF 293
+ + LSGGE QRVA+ + K + L+DE ++ LD S +R + A + K
Sbjct: 173 EGYRTQVGERGLKLSGGEKQRVAIARTILKAPGIILLDEATSALDTSNERAIQASLAK-- 230
Query: 292 ILHAKRTGFVVEHDFIMATYLADRVIVFE 206
+ A RT VV H + AD+++V +
Sbjct: 231 -VCANRTTIVVAHR-LSTVVNADQILVIK 257
>BC000559-1|AAH00559.1| 842|Homo sapiens ATP-binding cassette,
sub-family B (MDR/TAP), member 6 protein.
Length = 842
Score = 47.2 bits (107), Expect = 7e-05
Identities = 55/209 (26%), Positives = 90/209 (43%), Gaps = 21/209 (10%)
Frame = -3
Query: 769 YPEMXKMMGDFGLRVMPGEFSDSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLH 590
Y + + + D VMPG+ L L+G +G GK+T +R+L + G ++
Sbjct: 599 YADGRETLQDVSFTVMPGQ-----TLALVGPSGAGKSTILRLLFRFYDISSGCIRIDGQD 653
Query: 589 ISYKPQK-------ISPKSQGLVRSLLHDKIR-----------DAYIHPQFLTDVMK--P 470
IS Q + P+ L + D IR +A + D + P
Sbjct: 654 ISQVTQASLRSHIGVVPQDTVLFNDTIADNIRYGRVTAGNDEVEAAAQAAGIHDAIMAFP 713
Query: 469 MKIEEIMDQEVQNLSGGELQRVALVLCLGKPADVYLIDEPSAYLD-SEQRLVAAKVIKRF 293
+ + LSGGE QRVA+ + K + L+DE ++ LD S +R + A + K
Sbjct: 714 EGYRTQVGERGLKLSGGEKQRVAIARTILKAPGIILLDEATSALDTSNERAIQASLAK-- 771
Query: 292 ILHAKRTGFVVEHDFIMATYLADRVIVFE 206
+ A RT VV H + AD+++V +
Sbjct: 772 -VCANRTTIVVAHR-LSTVVNADQILVIK 798
>AK074491-1|BAC11021.1| 483|Homo sapiens protein ( Homo sapiens
cDNA FLJ90010 fis, clone HEMBA1000349, weakly similar to
ATP-BINDING CASSETTE TRANSPORTER 1. ).
Length = 483
Score = 47.2 bits (107), Expect = 7e-05
Identities = 44/146 (30%), Positives = 69/146 (47%), Gaps = 18/146 (12%)
Frame = -3
Query: 706 DSEILVLLGENGTGKTTFIRMLAGNLEPDEGS--------GQLPQLHISYKPQKISPKSQ 551
+ +I LLG +G GKTT + +L+G P GS ++ + K P+S
Sbjct: 136 EGQITALLGHSGAGKTTLLNILSGLSVPTSGSVTVYNHTLSRMADIENISKFTGFCPQSN 195
Query: 550 GLVRSL-------LHDKIRDAYIHP--QFLTDVMKPMKIEEIMDQEVQNLSGGELQRVAL 398
L L KI+ H + + V++ +++E I D QNLSGG+ +++
Sbjct: 196 VQFGFLTVKENLRLFAKIKGILPHEVEKEVQRVVQELEMENIQDILAQNLSGGQNRKLTF 255
Query: 397 -VLCLGKPADVYLIDEPSAYLDSEQR 323
+ LG P V L+DEP+A LD R
Sbjct: 256 GIAILGDP-QVLLLDEPTAGLDPLSR 280
>AK057068-1|BAB71359.1| 856|Homo sapiens protein ( Homo sapiens
cDNA FLJ32506 fis, clone SMINT1000042, weakly similar to
ATP-BINDING CASSETTE, SUB-FAMILY A, MEMBER 3. ).
Length = 856
Score = 47.2 bits (107), Expect = 7e-05
Identities = 44/146 (30%), Positives = 69/146 (47%), Gaps = 18/146 (12%)
Frame = -3
Query: 706 DSEILVLLGENGTGKTTFIRMLAGNLEPDEGS--------GQLPQLHISYKPQKISPKSQ 551
+ +I LLG +G GKTT + +L+G P GS ++ + K P+S
Sbjct: 509 EGQITALLGHSGAGKTTLLNILSGLSVPTSGSVTVYNHTLSRMADIENISKFTGFCPQSN 568
Query: 550 GLVRSL-------LHDKIRDAYIHP--QFLTDVMKPMKIEEIMDQEVQNLSGGELQRVAL 398
L L KI+ H + + V++ +++E I D QNLSGG+ +++
Sbjct: 569 VQFGFLTVKENLRLFAKIKGILPHEVEKEVQRVVQELEMENIQDILAQNLSGGQNRKLTF 628
Query: 397 -VLCLGKPADVYLIDEPSAYLDSEQR 323
+ LG P V L+DEP+A LD R
Sbjct: 629 GIAILGDP-QVLLLDEPTAGLDPLSR 653
>AK057026-1|BAB71347.1| 766|Homo sapiens protein ( Homo sapiens cDNA
FLJ32464 fis, clone SKNMC1000251, highly similar to Homo
sapiens MT-ABC transporter (MTABC) mRNA. ).
Length = 766
Score = 47.2 bits (107), Expect = 7e-05
Identities = 55/209 (26%), Positives = 90/209 (43%), Gaps = 21/209 (10%)
Frame = -3
Query: 769 YPEMXKMMGDFGLRVMPGEFSDSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLH 590
Y + + + D VMPG+ L L+G +G GK+T +R+L + G ++
Sbjct: 523 YADGRETLQDVSFTVMPGQ-----TLALVGPSGAGKSTILRLLFRFYDISSGCIRIDGQD 577
Query: 589 ISYKPQK-------ISPKSQGLVRSLLHDKIR-----------DAYIHPQFLTDVMK--P 470
IS Q + P+ L + D IR +A + D + P
Sbjct: 578 ISQVTQASLRSHIGVVPQDTVLFNDTIADNIRYGRVTAGNDEVEAAAQAAGIHDAIMAFP 637
Query: 469 MKIEEIMDQEVQNLSGGELQRVALVLCLGKPADVYLIDEPSAYLD-SEQRLVAAKVIKRF 293
+ + LSGGE QRVA+ + K + L+DE ++ LD S +R + A + K
Sbjct: 638 EGYRTQVGERGLKLSGGEKQRVAIARTILKAPGIILLDEATSALDTSNERAIQASLAK-- 695
Query: 292 ILHAKRTGFVVEHDFIMATYLADRVIVFE 206
+ A RT VV H + AD+++V +
Sbjct: 696 -VCANRTTIVVAHR-LSTVVNADQILVIK 722
>AJ289233-1|CAB95766.2| 842|Homo sapiens ABC transporter umat
protein.
Length = 842
Score = 47.2 bits (107), Expect = 7e-05
Identities = 55/209 (26%), Positives = 90/209 (43%), Gaps = 21/209 (10%)
Frame = -3
Query: 769 YPEMXKMMGDFGLRVMPGEFSDSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLH 590
Y + + + D VMPG+ L L+G +G GK+T +R+L + G ++
Sbjct: 599 YADGRETLQDVSFTVMPGQ-----TLALVGPSGAGKSTILRLLFRFYDISSGCIRIDGQD 653
Query: 589 ISYKPQK-------ISPKSQGLVRSLLHDKIR-----------DAYIHPQFLTDVMK--P 470
IS Q + P+ L + D IR +A + D + P
Sbjct: 654 ISQVTQASLRSHIGVVPQDTVLFNDTIADNIRYGRVTAGNDEVEAAAQAAGIHDAIMAFP 713
Query: 469 MKIEEIMDQEVQNLSGGELQRVALVLCLGKPADVYLIDEPSAYLD-SEQRLVAAKVIKRF 293
+ + LSGGE QRVA+ + K + L+DE ++ LD S +R + A + K
Sbjct: 714 EGYRTQVGERGLKLSGGEKQRVAIARTILKAPGIILLDEATSALDTSNERAIQASLAK-- 771
Query: 292 ILHAKRTGFVVEHDFIMATYLADRVIVFE 206
+ A RT VV H + AD+++V +
Sbjct: 772 -VCANRTTIVVAHR-LSTVVNADQILVIK 798
>AF308472-1|AAG33617.1| 896|Homo sapiens ATP-binding cassette
half-transporter protein.
Length = 896
Score = 47.2 bits (107), Expect = 7e-05
Identities = 55/209 (26%), Positives = 90/209 (43%), Gaps = 21/209 (10%)
Frame = -3
Query: 769 YPEMXKMMGDFGLRVMPGEFSDSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLH 590
Y + + + D VMPG+ L L+G +G GK+T +R+L + G ++
Sbjct: 653 YADGRETLQDVSFTVMPGQ-----TLALVGPSGAGKSTILRLLFRFYDISSGCIRIDGQD 707
Query: 589 ISYKPQK-------ISPKSQGLVRSLLHDKIR-----------DAYIHPQFLTDVMK--P 470
IS Q + P+ L + D IR +A + D + P
Sbjct: 708 ISQVTQASLRSHIGVVPQDTVLFNDTIADNIRYGRVTAGNDEVEAAAQAAGIHDAIMAFP 767
Query: 469 MKIEEIMDQEVQNLSGGELQRVALVLCLGKPADVYLIDEPSAYLD-SEQRLVAAKVIKRF 293
+ + LSGGE QRVA+ + K + L+DE ++ LD S +R + A + K
Sbjct: 768 EGYRTQVGERGLKLSGGEKQRVAIARTILKAPGIILLDEATSALDTSNERAIQASLAK-- 825
Query: 292 ILHAKRTGFVVEHDFIMATYLADRVIVFE 206
+ A RT VV H + AD+++V +
Sbjct: 826 -VCANRTTIVVAHR-LSTVVNADQILVIK 852
>AF076775-1|AAF75107.1| 842|Homo sapiens MT-ABC transporter protein.
Length = 842
Score = 47.2 bits (107), Expect = 7e-05
Identities = 55/209 (26%), Positives = 90/209 (43%), Gaps = 21/209 (10%)
Frame = -3
Query: 769 YPEMXKMMGDFGLRVMPGEFSDSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLH 590
Y + + + D VMPG+ L L+G +G GK+T +R+L + G ++
Sbjct: 599 YADGRETLQDVSFTVMPGQ-----TLALVGPSGAGKSTILRLLFRFYDISSGCIRIDGQD 653
Query: 589 ISYKPQK-------ISPKSQGLVRSLLHDKIR-----------DAYIHPQFLTDVMK--P 470
IS Q + P+ L + D IR +A + D + P
Sbjct: 654 ISQVTQASLRSHIGVVPQDTVLFNDTIADNIRYGRVTAGNDEVEAAAQAAGIHDAIMAFP 713
Query: 469 MKIEEIMDQEVQNLSGGELQRVALVLCLGKPADVYLIDEPSAYLD-SEQRLVAAKVIKRF 293
+ + LSGGE QRVA+ + K + L+DE ++ LD S +R + A + K
Sbjct: 714 EGYRTQVGERGLKLSGGEKQRVAIARTILKAPGIILLDEATSALDTSNERAIQASLAK-- 771
Query: 292 ILHAKRTGFVVEHDFIMATYLADRVIVFE 206
+ A RT VV H + AD+++V +
Sbjct: 772 -VCANRTTIVVAHR-LSTVVNADQILVIK 798
>AF070598-1|AAC28653.1| 511|Homo sapiens ABC transporter protein.
Length = 511
Score = 47.2 bits (107), Expect = 7e-05
Identities = 55/209 (26%), Positives = 90/209 (43%), Gaps = 21/209 (10%)
Frame = -3
Query: 769 YPEMXKMMGDFGLRVMPGEFSDSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLH 590
Y + + + D VMPG+ L L+G +G GK+T +R+L + G ++
Sbjct: 268 YADGRETLQDVSFTVMPGQ-----TLALVGPSGAGKSTILRLLFRFYDISSGCIRIDGQD 322
Query: 589 ISYKPQK-------ISPKSQGLVRSLLHDKIR-----------DAYIHPQFLTDVMK--P 470
IS Q + P+ L + D IR +A + D + P
Sbjct: 323 ISQVTQASLRSHIGVVPQDTVLFNDTIADNIRYGRVTAGNDEVEAAAQAAGIHDAIMAFP 382
Query: 469 MKIEEIMDQEVQNLSGGELQRVALVLCLGKPADVYLIDEPSAYLD-SEQRLVAAKVIKRF 293
+ + LSGGE QRVA+ + K + L+DE ++ LD S +R + A + K
Sbjct: 383 EGYRTQVGERGLKLSGGEKQRVAIARTILKAPGIILLDEATSALDTSNERAIQASLAK-- 440
Query: 292 ILHAKRTGFVVEHDFIMATYLADRVIVFE 206
+ A RT VV H + AD+++V +
Sbjct: 441 -VCANRTTIVVAHR-LSTVVNADQILVIK 467
>AB039371-1|BAA96733.1| 842|Homo sapiens mitochondrial ABC
transporter 3 protein.
Length = 842
Score = 47.2 bits (107), Expect = 7e-05
Identities = 55/209 (26%), Positives = 90/209 (43%), Gaps = 21/209 (10%)
Frame = -3
Query: 769 YPEMXKMMGDFGLRVMPGEFSDSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLH 590
Y + + + D VMPG+ L L+G +G GK+T +R+L + G ++
Sbjct: 599 YADGRETLQDVSFTVMPGQ-----TLALVGPSGAGKSTILRLLFRFYDISSGCIRIDGQD 653
Query: 589 ISYKPQK-------ISPKSQGLVRSLLHDKIR-----------DAYIHPQFLTDVMK--P 470
IS Q + P+ L + D IR +A + D + P
Sbjct: 654 ISQVTQASLRSHIGVVPQDTVLFNDTIADNIRYGRVTAGNDEVEAAAQAAGIHDAIMAFP 713
Query: 469 MKIEEIMDQEVQNLSGGELQRVALVLCLGKPADVYLIDEPSAYLD-SEQRLVAAKVIKRF 293
+ + LSGGE QRVA+ + K + L+DE ++ LD S +R + A + K
Sbjct: 714 EGYRTQVGERGLKLSGGEKQRVAIARTILKAPGIILLDEATSALDTSNERAIQASLAK-- 771
Query: 292 ILHAKRTGFVVEHDFIMATYLADRVIVFE 206
+ A RT VV H + AD+++V +
Sbjct: 772 -VCANRTTIVVAHR-LSTVVNADQILVIK 798
>AB353947-1|BAF75364.1| 1257|Homo sapiens ATP-binding cassette,
sub-family B (MDR/TAP), member 5 protein.
Length = 1257
Score = 46.8 bits (106), Expect = 9e-05
Identities = 49/222 (22%), Positives = 95/222 (42%), Gaps = 20/222 (9%)
Frame = -3
Query: 754 KMMGDFGLRVMPGEFSDSEILVLLGENGTGKTTFIRMLAGNLEPDEG-----SGQLPQLH 590
K++ LR+ GE + L+G NG+GK+T +++L +PD+G + L+
Sbjct: 402 KILKGLNLRIKSGE-----TVALVGLNGSGKSTVVQLLQRLYDPDDGFIMVDENDIRALN 456
Query: 589 ISYKPQKISPKSQGLVR--------------SLLHDKIRDAYIHPQFLTDVMK-PMKIEE 455
+ + I SQ V + +++ A +M+ P K
Sbjct: 457 VRHYRDHIGVVSQEPVLFGTTISNNIKYGRDDVTDEEMERAAREANAYDFIMEFPNKFNT 516
Query: 454 IMDQEVQNLSGGELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKR 275
++ ++ +SGG+ QR+A+ L + + ++DE ++ LDSE + +++ R
Sbjct: 517 LVGEKGAQMSGGQKQRIAIARALVRNPKILILDEATSALDSESKSAVQAALEK--ASKGR 574
Query: 274 TGFVVEHDFIMATYLADRVIVFEGTPSSNATAHAPQSLLNGM 149
T VV H + AD ++ + + AHA G+
Sbjct: 575 TTIVVAHR-LSTIRSADLIVTLKDGMLAEKGAHAELMAKRGL 615
Score = 37.9 bits (84), Expect = 0.041
Identities = 28/101 (27%), Positives = 47/101 (46%)
Frame = -3
Query: 430 LSGGELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHD 251
LSGG+ QR+A+ L + + L+DE ++ LD++ V + + RT VV H
Sbjct: 1156 LSGGQKQRLAIARALLQKPKILLLDEATSALDNDSEKVVQHALDK--ARTGRTCLVVTHR 1213
Query: 250 FIMATYLADRVIVFEGTPSSNATAHAPQSLLNGMNKFLELL 128
+ A AD ++V H Q LL + + +L+
Sbjct: 1214 -LSAIQNADLIVVLHNGKIKEQGTH--QELLRNRDIYFKLV 1251
>BT009918-1|AAP88920.1| 753|Homo sapiens ATP-binding cassette,
sub-family B (MDR/TAP), member 7 protein.
Length = 753
Score = 46.4 bits (105), Expect = 1e-04
Identities = 66/261 (25%), Positives = 113/261 (43%), Gaps = 26/261 (9%)
Frame = -3
Query: 736 GLRVMPG---EFSDSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQKI 566
G +V+ G E + + ++G +G+GK+T +R+L EP +GS L +I +
Sbjct: 485 GQKVLSGISFEVPAGKKVAIVGGSGSGKSTIVRLLFRFYEPQKGSIYLAGQNIQDVSLES 544
Query: 565 SPKSQGLVRS---LLHDKIRDAYIH------PQFLTDVMKPMKIEEIM-------DQEVQ 434
++ G+V L H+ I ++ P+ + V K + + + D +V
Sbjct: 545 LRRAVGVVPQDAVLFHNTIYYNLLYGNISASPEEVYAVAKLAGLHDAILRMPHGYDTQVG 604
Query: 433 N----LSGGELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGF 266
LSGGE QRVA+ + K V L DE ++ LDS +K + H RT
Sbjct: 605 ERGLKLSGGEKQRVAIARAILKDPPVILYDEATSSLDSITEETILGAMKDVVKH--RTSI 662
Query: 265 VVEHDFIMATYLADRVIVF-EGTPSSNATAHAPQSLLNGMNKFLELLGITFRRDPNNFRP 89
+ H + AD +IV +G + T H L N + + E+ R N+ P
Sbjct: 663 FIAHR-LSTVVDADEIIVLDQGKVAERGTHHG--LLANPHSIYSEMWHTQSSRVQNHDNP 719
Query: 88 R--INKHASVKDIEQKRAGQD 32
+ K K+ E+K+ ++
Sbjct: 720 KWEAKKENISKEEERKKLQEE 740
>BC006323-1|AAH06323.1| 753|Homo sapiens ATP-binding cassette,
sub-family B (MDR/TAP), member 7 protein.
Length = 753
Score = 46.4 bits (105), Expect = 1e-04
Identities = 66/261 (25%), Positives = 113/261 (43%), Gaps = 26/261 (9%)
Frame = -3
Query: 736 GLRVMPG---EFSDSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQKI 566
G +V+ G E + + ++G +G+GK+T +R+L EP +GS L +I +
Sbjct: 485 GQKVLSGISFEVPAGKKVAIVGGSGSGKSTIVRLLFRFYEPQKGSIYLAGQNIQDVSLES 544
Query: 565 SPKSQGLVRS---LLHDKIRDAYIH------PQFLTDVMKPMKIEEIM-------DQEVQ 434
++ G+V L H+ I ++ P+ + V K + + + D +V
Sbjct: 545 LRRAVGVVPQDAVLFHNTIYYNLLYGNISASPEEVYAVAKLAGLHDAILRMPHGYDTQVG 604
Query: 433 N----LSGGELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGF 266
LSGGE QRVA+ + K V L DE ++ LDS +K + H RT
Sbjct: 605 ERGLKLSGGEKQRVAIARAILKDPPVILYDEATSSLDSITEETILGAMKDVVKH--RTSI 662
Query: 265 VVEHDFIMATYLADRVIVF-EGTPSSNATAHAPQSLLNGMNKFLELLGITFRRDPNNFRP 89
+ H + AD +IV +G + T H L N + + E+ R N+ P
Sbjct: 663 FIAHR-LSTVVDADEIIVLDQGKVAERGTHHG--LLANPHSIYSEMWHTQSSRVQNHDNP 719
Query: 88 R--INKHASVKDIEQKRAGQD 32
+ K K+ E+K+ ++
Sbjct: 720 KWEAKKENISKEEERKKLQEE 740
>AL360179-2|CAH70564.1| 753|Homo sapiens ATP-binding cassette,
sub-family B (MDR/TAP), member 7 protein.
Length = 753
Score = 46.4 bits (105), Expect = 1e-04
Identities = 66/261 (25%), Positives = 113/261 (43%), Gaps = 26/261 (9%)
Frame = -3
Query: 736 GLRVMPG---EFSDSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQKI 566
G +V+ G E + + ++G +G+GK+T +R+L EP +GS L +I +
Sbjct: 485 GQKVLSGISFEVPAGKKVAIVGGSGSGKSTIVRLLFRFYEPQKGSIYLAGQNIQDVSLES 544
Query: 565 SPKSQGLVRS---LLHDKIRDAYIH------PQFLTDVMKPMKIEEIM-------DQEVQ 434
++ G+V L H+ I ++ P+ + V K + + + D +V
Sbjct: 545 LRRAVGVVPQDAVLFHNTIYYNLLYGNISASPEEVYAVAKLAGLHDAILRMPHGYDTQVG 604
Query: 433 N----LSGGELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGF 266
LSGGE QRVA+ + K V L DE ++ LDS +K + H RT
Sbjct: 605 ERGLKLSGGEKQRVAIARAILKDPPVILYDEATSSLDSITEETILGAMKDVVKH--RTSI 662
Query: 265 VVEHDFIMATYLADRVIVF-EGTPSSNATAHAPQSLLNGMNKFLELLGITFRRDPNNFRP 89
+ H + AD +IV +G + T H L N + + E+ R N+ P
Sbjct: 663 FIAHR-LSTVVDADEIIVLDQGKVAERGTHHG--LLANPHSIYSEMWHTQSSRVQNHDNP 719
Query: 88 R--INKHASVKDIEQKRAGQD 32
+ K K+ E+K+ ++
Sbjct: 720 KWEAKKENISKEEERKKLQEE 740
>AL360179-1|CAH70565.1| 752|Homo sapiens ATP-binding cassette,
sub-family B (MDR/TAP), member 7 protein.
Length = 752
Score = 46.4 bits (105), Expect = 1e-04
Identities = 66/261 (25%), Positives = 113/261 (43%), Gaps = 26/261 (9%)
Frame = -3
Query: 736 GLRVMPG---EFSDSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQKI 566
G +V+ G E + + ++G +G+GK+T +R+L EP +GS L +I +
Sbjct: 484 GQKVLSGISFEVPAGKKVAIVGGSGSGKSTIVRLLFRFYEPQKGSIYLAGQNIQDVSLES 543
Query: 565 SPKSQGLVRS---LLHDKIRDAYIH------PQFLTDVMKPMKIEEIM-------DQEVQ 434
++ G+V L H+ I ++ P+ + V K + + + D +V
Sbjct: 544 LRRAVGVVPQDAVLFHNTIYYNLLYGNISASPEEVYAVAKLAGLHDAILRMPHGYDTQVG 603
Query: 433 N----LSGGELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGF 266
LSGGE QRVA+ + K V L DE ++ LDS +K + H RT
Sbjct: 604 ERGLKLSGGEKQRVAIARAILKDPPVILYDEATSSLDSITEETILGAMKDVVKH--RTSI 661
Query: 265 VVEHDFIMATYLADRVIVF-EGTPSSNATAHAPQSLLNGMNKFLELLGITFRRDPNNFRP 89
+ H + AD +IV +G + T H L N + + E+ R N+ P
Sbjct: 662 FIAHR-LSTVVDADEIIVLDQGKVAERGTHHG--LLANPHSIYSEMWHTQSSRVQNHDNP 718
Query: 88 R--INKHASVKDIEQKRAGQD 32
+ K K+ E+K+ ++
Sbjct: 719 KWEAKKENISKEEERKKLQEE 739
>AL359545-2|CAI41574.1| 753|Homo sapiens ATP-binding cassette,
sub-family B (MDR/TAP), member 7 protein.
Length = 753
Score = 46.4 bits (105), Expect = 1e-04
Identities = 66/261 (25%), Positives = 113/261 (43%), Gaps = 26/261 (9%)
Frame = -3
Query: 736 GLRVMPG---EFSDSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQKI 566
G +V+ G E + + ++G +G+GK+T +R+L EP +GS L +I +
Sbjct: 485 GQKVLSGISFEVPAGKKVAIVGGSGSGKSTIVRLLFRFYEPQKGSIYLAGQNIQDVSLES 544
Query: 565 SPKSQGLVRS---LLHDKIRDAYIH------PQFLTDVMKPMKIEEIM-------DQEVQ 434
++ G+V L H+ I ++ P+ + V K + + + D +V
Sbjct: 545 LRRAVGVVPQDAVLFHNTIYYNLLYGNISASPEEVYAVAKLAGLHDAILRMPHGYDTQVG 604
Query: 433 N----LSGGELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGF 266
LSGGE QRVA+ + K V L DE ++ LDS +K + H RT
Sbjct: 605 ERGLKLSGGEKQRVAIARAILKDPPVILYDEATSSLDSITEETILGAMKDVVKH--RTSI 662
Query: 265 VVEHDFIMATYLADRVIVF-EGTPSSNATAHAPQSLLNGMNKFLELLGITFRRDPNNFRP 89
+ H + AD +IV +G + T H L N + + E+ R N+ P
Sbjct: 663 FIAHR-LSTVVDADEIIVLDQGKVAERGTHHG--LLANPHSIYSEMWHTQSSRVQNHDNP 719
Query: 88 R--INKHASVKDIEQKRAGQD 32
+ K K+ E+K+ ++
Sbjct: 720 KWEAKKENISKEEERKKLQEE 740
>AL359545-1|CAI41573.1| 752|Homo sapiens ATP-binding cassette,
sub-family B (MDR/TAP), member 7 protein.
Length = 752
Score = 46.4 bits (105), Expect = 1e-04
Identities = 66/261 (25%), Positives = 113/261 (43%), Gaps = 26/261 (9%)
Frame = -3
Query: 736 GLRVMPG---EFSDSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQKI 566
G +V+ G E + + ++G +G+GK+T +R+L EP +GS L +I +
Sbjct: 484 GQKVLSGISFEVPAGKKVAIVGGSGSGKSTIVRLLFRFYEPQKGSIYLAGQNIQDVSLES 543
Query: 565 SPKSQGLVRS---LLHDKIRDAYIH------PQFLTDVMKPMKIEEIM-------DQEVQ 434
++ G+V L H+ I ++ P+ + V K + + + D +V
Sbjct: 544 LRRAVGVVPQDAVLFHNTIYYNLLYGNISASPEEVYAVAKLAGLHDAILRMPHGYDTQVG 603
Query: 433 N----LSGGELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGF 266
LSGGE QRVA+ + K V L DE ++ LDS +K + H RT
Sbjct: 604 ERGLKLSGGEKQRVAIARAILKDPPVILYDEATSSLDSITEETILGAMKDVVKH--RTSI 661
Query: 265 VVEHDFIMATYLADRVIVF-EGTPSSNATAHAPQSLLNGMNKFLELLGITFRRDPNNFRP 89
+ H + AD +IV +G + T H L N + + E+ R N+ P
Sbjct: 662 FIAHR-LSTVVDADEIIVLDQGKVAERGTHHG--LLANPHSIYSEMWHTQSSRVQNHDNP 718
Query: 88 R--INKHASVKDIEQKRAGQD 32
+ K K+ E+K+ ++
Sbjct: 719 KWEAKKENISKEEERKKLQEE 739
>AF241887-1|AAK20173.1| 752|Homo sapiens ATP binding cassette 7
protein.
Length = 752
Score = 46.4 bits (105), Expect = 1e-04
Identities = 66/261 (25%), Positives = 113/261 (43%), Gaps = 26/261 (9%)
Frame = -3
Query: 736 GLRVMPG---EFSDSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQKI 566
G +V+ G E + + ++G +G+GK+T +R+L EP +GS L +I +
Sbjct: 484 GQKVLSGISFEVPAGKKVAIVGGSGSGKSTIVRLLFRFYEPQKGSIYLAGQNIQDVSLES 543
Query: 565 SPKSQGLVRS---LLHDKIRDAYIH------PQFLTDVMKPMKIEEIM-------DQEVQ 434
++ G+V L H+ I ++ P+ + V K + + + D +V
Sbjct: 544 LRRAVGVVPQDAVLFHNTIYYNLLYGNISASPEEVYAVAKLAGLHDAILRMPHGYDTQVG 603
Query: 433 N----LSGGELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGF 266
LSGGE QRVA+ + K V L DE ++ LDS +K + H RT
Sbjct: 604 ERGLKLSGGEKQRVAIARAILKDPPVILYDEATSSLDSITEETILGAMKDVVKH--RTSI 661
Query: 265 VVEHDFIMATYLADRVIVF-EGTPSSNATAHAPQSLLNGMNKFLELLGITFRRDPNNFRP 89
+ H + AD +IV +G + T H L N + + E+ R N+ P
Sbjct: 662 FIAHR-LSTVVDADEIIVLDQGKVAERGTHHG--LLANPHSIYSEMWHTQSSRVQNHDNP 718
Query: 88 R--INKHASVKDIEQKRAGQD 32
+ K K+ E+K+ ++
Sbjct: 719 KWEAKKENISKEEERKKLQEE 739
>AF133659-1|AAD33045.1| 752|Homo sapiens ATP-binding cassette 7 iron
transporter protein.
Length = 752
Score = 46.4 bits (105), Expect = 1e-04
Identities = 66/261 (25%), Positives = 113/261 (43%), Gaps = 26/261 (9%)
Frame = -3
Query: 736 GLRVMPG---EFSDSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQKI 566
G +V+ G E + + ++G +G+GK+T +R+L EP +GS L +I +
Sbjct: 484 GQKVLSGISFEVPAGKKVAIVGGSGSGKSTIVRLLFRFYEPQKGSIYLAGQNIQDVSLES 543
Query: 565 SPKSQGLVRS---LLHDKIRDAYIH------PQFLTDVMKPMKIEEIM-------DQEVQ 434
++ G+V L H+ I ++ P+ + V K + + + D +V
Sbjct: 544 LRRAVGVVPQDAVLFHNTIYYNLLYGNISASPEEVYAVAKLAGLHDAILRMPHGYDTQVG 603
Query: 433 N----LSGGELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGF 266
LSGGE QRVA+ + K V L DE ++ LDS +K + H RT
Sbjct: 604 ERGLKLSGGEKQRVAIARAILKDPPVILYDEATSSLDSITEETILGAMKDVVKH--RTSI 661
Query: 265 VVEHDFIMATYLADRVIVF-EGTPSSNATAHAPQSLLNGMNKFLELLGITFRRDPNNFRP 89
+ H + AD +IV +G + T H L N + + E+ R N+ P
Sbjct: 662 FIAHR-LSTVVDADEIIVLDQGKVAERGTHHG--LLANPHSIYSEMWHTQSSRVQNHDNP 718
Query: 88 R--INKHASVKDIEQKRAGQD 32
+ K K+ E+K+ ++
Sbjct: 719 KWEAKKENISKEEERKKLQEE 739
>AB005289-1|BAA28861.1| 752|Homo sapiens ABC transporter 7 protein
protein.
Length = 752
Score = 46.4 bits (105), Expect = 1e-04
Identities = 66/261 (25%), Positives = 113/261 (43%), Gaps = 26/261 (9%)
Frame = -3
Query: 736 GLRVMPG---EFSDSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQKI 566
G +V+ G E + + ++G +G+GK+T +R+L EP +GS L +I +
Sbjct: 484 GQKVLSGISFEVPAGKKVAIVGGSGSGKSTIVRLLFRFYEPQKGSIYLAGQNIQDVSLES 543
Query: 565 SPKSQGLVRS---LLHDKIRDAYIH------PQFLTDVMKPMKIEEIM-------DQEVQ 434
++ G+V L H+ I ++ P+ + V K + + + D +V
Sbjct: 544 LRRAVGVVPQDAVLFHNTIYYNLLYGNISASPEEVYAVAKLAGLHDAILRMPHGYDTQVG 603
Query: 433 N----LSGGELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGF 266
LSGGE QRVA+ + K V L DE ++ LDS +K + H RT
Sbjct: 604 ERGLKLSGGEKQRVAIARAILKDPPVILYDEATSSLDSITEETILGAMKDVVKH--RTSI 661
Query: 265 VVEHDFIMATYLADRVIVF-EGTPSSNATAHAPQSLLNGMNKFLELLGITFRRDPNNFRP 89
+ H + AD +IV +G + T H L N + + E+ R N+ P
Sbjct: 662 FIAHR-LSTVVDADEIIVLDQGKVAERGTHHG--LLANPHSIYSEMWHTQSSRVQNHDNP 718
Query: 88 R--INKHASVKDIEQKRAGQD 32
+ K K+ E+K+ ++
Sbjct: 719 KWEAKKENISKEEERKKLQEE 739
>BC041560-1|AAH41560.1| 859|Homo sapiens ABCC4 protein protein.
Length = 859
Score = 46.0 bits (104), Expect = 2e-04
Identities = 45/158 (28%), Positives = 77/158 (48%), Gaps = 9/158 (5%)
Frame = -3
Query: 700 EILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLH--ISYKPQKISPKSQGLVRSLLH 527
E+L ++G G GK++ + + G L P G L +H I+Y Q+ S L ++L
Sbjct: 439 ELLAVVGPVGAGKSSLLSAVLGELAPSHG---LVSVHGRIAYVSQQPWVFSGTLRSNILF 495
Query: 526 DKIRDAYIHPQFLTD--VMKPMKIEEIMDQEV-----QNLSGGELQRVALVLCLGKPADV 368
K + + + + + K +++ E D V LSGG+ RV L + + AD+
Sbjct: 496 GKKYEKERYEKVIKACALKKDLQLLEDGDLTVIGDRGTTLSGGQKARVNLARAVYQDADI 555
Query: 367 YLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEH 254
YL+D+P + +D+E ++ ILH K T +V H
Sbjct: 556 YLLDDPLSAVDAEVSRHLFELCICQILHEKIT-ILVTH 592
>AY207008-1|AAO37649.1| 1325|Homo sapiens ATP-binding cassette
transporter C4 protein.
Length = 1325
Score = 46.0 bits (104), Expect = 2e-04
Identities = 45/158 (28%), Positives = 77/158 (48%), Gaps = 9/158 (5%)
Frame = -3
Query: 700 EILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLH--ISYKPQKISPKSQGLVRSLLH 527
E+L ++G G GK++ + + G L P G L +H I+Y Q+ S L ++L
Sbjct: 439 ELLAVVGPVGAGKSSLLSAVLGELAPSHG---LVSVHGRIAYVSQQPWVFSGTLRSNILF 495
Query: 526 DKIRDAYIHPQFLTD--VMKPMKIEEIMDQEV-----QNLSGGELQRVALVLCLGKPADV 368
K + + + + + K +++ E D V LSGG+ RV L + + AD+
Sbjct: 496 GKKYEKERYEKVIKACALKKDLQLLEDGDLTVIGDRGTTLSGGQKARVNLARAVYQDADI 555
Query: 367 YLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEH 254
YL+D+P + +D+E ++ ILH K T +V H
Sbjct: 556 YLLDDPLSAVDAEVSRHLFELCICQILHEKIT-ILVTH 592
Score = 30.3 bits (65), Expect = 8.2
Identities = 46/193 (23%), Positives = 77/193 (39%), Gaps = 25/193 (12%)
Frame = -3
Query: 745 GDFGLRVMPGEFSDSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQ-------LHI 587
G L+ + E + ++G G GK++ I L EP EG + + LH
Sbjct: 1054 GPLVLKHLTALIKSQEKVGIVGRTGAGKSSLISALFRLSEP-EGKIWIDKILTTEIGLHD 1112
Query: 586 SYKPQKISPKSQGLVRSLLHDKIRDAYIHP-----QFLTDVMKPMKIEEI---MDQEV-- 437
K I P+ L + + H L +V IE++ MD E+
Sbjct: 1113 LRKKMSIIPQEPVLFTGTMRKNLDPFNEHTDEELWNALQEVQLKETIEDLPGKMDTELAE 1172
Query: 436 --QNLSGGELQRVALVLCLGKPADVYLIDEPSAYLDSE-QRLVAAKVIKRF-----ILHA 281
N S G+ Q V L + + + +IDE +A +D L+ K+ ++F + A
Sbjct: 1173 SGSNFSVGQRQLVCLARAILRKNQILIIDEATANVDPRTDELIQKKIREKFAHCTVLTIA 1232
Query: 280 KRTGFVVEHDFIM 242
R +++ D IM
Sbjct: 1233 HRLNTIIDSDKIM 1245
>AY081219-1|AAL88745.1| 1325|Homo sapiens multidrug
resistance-associated protein protein.
Length = 1325
Score = 46.0 bits (104), Expect = 2e-04
Identities = 45/158 (28%), Positives = 77/158 (48%), Gaps = 9/158 (5%)
Frame = -3
Query: 700 EILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLH--ISYKPQKISPKSQGLVRSLLH 527
E+L ++G G GK++ + + G L P G L +H I+Y Q+ S L ++L
Sbjct: 439 ELLAVVGPVGAGKSSLLSAVLGELAPSHG---LVSVHGRIAYVSQQPWVFSGTLRSNILF 495
Query: 526 DKIRDAYIHPQFLTD--VMKPMKIEEIMDQEV-----QNLSGGELQRVALVLCLGKPADV 368
K + + + + + K +++ E D V LSGG+ RV L + + AD+
Sbjct: 496 GKKYEKERYEKVIKACALKKDLQLLEDGDLTVIGDRGTTLSGGQKARVNLARAVYQDADI 555
Query: 367 YLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEH 254
YL+D+P + +D+E ++ ILH K T +V H
Sbjct: 556 YLLDDPLSAVDAEVSRHLFELCICQILHEKIT-ILVTH 592
Score = 30.3 bits (65), Expect = 8.2
Identities = 46/193 (23%), Positives = 77/193 (39%), Gaps = 25/193 (12%)
Frame = -3
Query: 745 GDFGLRVMPGEFSDSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQ-------LHI 587
G L+ + E + ++G G GK++ I L EP EG + + LH
Sbjct: 1054 GPLVLKHLTALIKSQEKVGIVGRTGAGKSSLISALFRLSEP-EGKIWIDKILTTEIGLHD 1112
Query: 586 SYKPQKISPKSQGLVRSLLHDKIRDAYIHP-----QFLTDVMKPMKIEEI---MDQEV-- 437
K I P+ L + + H L +V IE++ MD E+
Sbjct: 1113 LRKKMSIIPQEPVLFTGTMRKNLDPFNEHTDEELWNALQEVQLKETIEDLPGKMDTELAE 1172
Query: 436 --QNLSGGELQRVALVLCLGKPADVYLIDEPSAYLDSE-QRLVAAKVIKRF-----ILHA 281
N S G+ Q V L + + + +IDE +A +D L+ K+ ++F + A
Sbjct: 1173 SGSNFSVGQRQLVCLARAILRKNQILIIDEATANVDPRTDELIQKKIREKFAHCTVLTIA 1232
Query: 280 KRTGFVVEHDFIM 242
R +++ D IM
Sbjct: 1233 HRLNTIIDSDKIM 1245
>AL356257-1|CAI16722.1| 1325|Homo sapiens ATP-binding cassette,
sub-family C (CFTR/MRP), member 4 protein.
Length = 1325
Score = 46.0 bits (104), Expect = 2e-04
Identities = 45/158 (28%), Positives = 77/158 (48%), Gaps = 9/158 (5%)
Frame = -3
Query: 700 EILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLH--ISYKPQKISPKSQGLVRSLLH 527
E+L ++G G GK++ + + G L P G L +H I+Y Q+ S L ++L
Sbjct: 439 ELLAVVGPVGAGKSSLLSAVLGELAPSHG---LVSVHGRIAYVSQQPWVFSGTLRSNILF 495
Query: 526 DKIRDAYIHPQFLTD--VMKPMKIEEIMDQEV-----QNLSGGELQRVALVLCLGKPADV 368
K + + + + + K +++ E D V LSGG+ RV L + + AD+
Sbjct: 496 GKKYEKERYEKVIKACALKKDLQLLEDGDLTVIGDRGTTLSGGQKARVNLARAVYQDADI 555
Query: 367 YLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEH 254
YL+D+P + +D+E ++ ILH K T +V H
Sbjct: 556 YLLDDPLSAVDAEVSRHLFELCICQILHEKIT-ILVTH 592
Score = 30.3 bits (65), Expect = 8.2
Identities = 46/193 (23%), Positives = 77/193 (39%), Gaps = 25/193 (12%)
Frame = -3
Query: 745 GDFGLRVMPGEFSDSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQ-------LHI 587
G L+ + E + ++G G GK++ I L EP EG + + LH
Sbjct: 1054 GPLVLKHLTALIKSQEKVGIVGRTGAGKSSLISALFRLSEP-EGKIWIDKILTTEIGLHD 1112
Query: 586 SYKPQKISPKSQGLVRSLLHDKIRDAYIHP-----QFLTDVMKPMKIEEI---MDQEV-- 437
K I P+ L + + H L +V IE++ MD E+
Sbjct: 1113 LRKKMSIIPQEPVLFTGTMRKNLDPFNEHTDEELWNALQEVQLKETIEDLPGKMDTELAE 1172
Query: 436 --QNLSGGELQRVALVLCLGKPADVYLIDEPSAYLDSE-QRLVAAKVIKRF-----ILHA 281
N S G+ Q V L + + + +IDE +A +D L+ K+ ++F + A
Sbjct: 1173 SGSNFSVGQRQLVCLARAILRKNQILIIDEATANVDPRTDELIQKKIREKFAHCTVLTIA 1232
Query: 280 KRTGFVVEHDFIM 242
R +++ D IM
Sbjct: 1233 HRLNTIIDSDKIM 1245
>AL157818-1|CAC36037.2| 1325|Homo sapiens ATP-binding cassette,
sub-family C (CFTR/MRP), member 4 protein.
Length = 1325
Score = 46.0 bits (104), Expect = 2e-04
Identities = 45/158 (28%), Positives = 77/158 (48%), Gaps = 9/158 (5%)
Frame = -3
Query: 700 EILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLH--ISYKPQKISPKSQGLVRSLLH 527
E+L ++G G GK++ + + G L P G L +H I+Y Q+ S L ++L
Sbjct: 439 ELLAVVGPVGAGKSSLLSAVLGELAPSHG---LVSVHGRIAYVSQQPWVFSGTLRSNILF 495
Query: 526 DKIRDAYIHPQFLTD--VMKPMKIEEIMDQEV-----QNLSGGELQRVALVLCLGKPADV 368
K + + + + + K +++ E D V LSGG+ RV L + + AD+
Sbjct: 496 GKKYEKERYEKVIKACALKKDLQLLEDGDLTVIGDRGTTLSGGQKARVNLARAVYQDADI 555
Query: 367 YLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEH 254
YL+D+P + +D+E ++ ILH K T +V H
Sbjct: 556 YLLDDPLSAVDAEVSRHLFELCICQILHEKIT-ILVTH 592
Score = 30.3 bits (65), Expect = 8.2
Identities = 46/193 (23%), Positives = 77/193 (39%), Gaps = 25/193 (12%)
Frame = -3
Query: 745 GDFGLRVMPGEFSDSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQ-------LHI 587
G L+ + E + ++G G GK++ I L EP EG + + LH
Sbjct: 1054 GPLVLKHLTALIKSQEKVGIVGRTGAGKSSLISALFRLSEP-EGKIWIDKILTTEIGLHD 1112
Query: 586 SYKPQKISPKSQGLVRSLLHDKIRDAYIHP-----QFLTDVMKPMKIEEI---MDQEV-- 437
K I P+ L + + H L +V IE++ MD E+
Sbjct: 1113 LRKKMSIIPQEPVLFTGTMRKNLDPFNEHTDEELWNALQEVQLKETIEDLPGKMDTELAE 1172
Query: 436 --QNLSGGELQRVALVLCLGKPADVYLIDEPSAYLDSE-QRLVAAKVIKRF-----ILHA 281
N S G+ Q V L + + + +IDE +A +D L+ K+ ++F + A
Sbjct: 1173 SGSNFSVGQRQLVCLARAILRKNQILIIDEATANVDPRTDELIQKKIREKFAHCTVLTIA 1232
Query: 280 KRTGFVVEHDFIM 242
R +++ D IM
Sbjct: 1233 HRLNTIIDSDKIM 1245
>AL139381-1|CAI16589.1| 1325|Homo sapiens ATP-binding cassette,
sub-family C (CFTR/MRP), member 4 protein.
Length = 1325
Score = 46.0 bits (104), Expect = 2e-04
Identities = 45/158 (28%), Positives = 77/158 (48%), Gaps = 9/158 (5%)
Frame = -3
Query: 700 EILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLH--ISYKPQKISPKSQGLVRSLLH 527
E+L ++G G GK++ + + G L P G L +H I+Y Q+ S L ++L
Sbjct: 439 ELLAVVGPVGAGKSSLLSAVLGELAPSHG---LVSVHGRIAYVSQQPWVFSGTLRSNILF 495
Query: 526 DKIRDAYIHPQFLTD--VMKPMKIEEIMDQEV-----QNLSGGELQRVALVLCLGKPADV 368
K + + + + + K +++ E D V LSGG+ RV L + + AD+
Sbjct: 496 GKKYEKERYEKVIKACALKKDLQLLEDGDLTVIGDRGTTLSGGQKARVNLARAVYQDADI 555
Query: 367 YLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEH 254
YL+D+P + +D+E ++ ILH K T +V H
Sbjct: 556 YLLDDPLSAVDAEVSRHLFELCICQILHEKIT-ILVTH 592
Score = 30.3 bits (65), Expect = 8.2
Identities = 46/193 (23%), Positives = 77/193 (39%), Gaps = 25/193 (12%)
Frame = -3
Query: 745 GDFGLRVMPGEFSDSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQ-------LHI 587
G L+ + E + ++G G GK++ I L EP EG + + LH
Sbjct: 1054 GPLVLKHLTALIKSQEKVGIVGRTGAGKSSLISALFRLSEP-EGKIWIDKILTTEIGLHD 1112
Query: 586 SYKPQKISPKSQGLVRSLLHDKIRDAYIHP-----QFLTDVMKPMKIEEI---MDQEV-- 437
K I P+ L + + H L +V IE++ MD E+
Sbjct: 1113 LRKKMSIIPQEPVLFTGTMRKNLDPFNEHTDEELWNALQEVQLKETIEDLPGKMDTELAE 1172
Query: 436 --QNLSGGELQRVALVLCLGKPADVYLIDEPSAYLDSE-QRLVAAKVIKRF-----ILHA 281
N S G+ Q V L + + + +IDE +A +D L+ K+ ++F + A
Sbjct: 1173 SGSNFSVGQRQLVCLARAILRKNQILIIDEATANVDPRTDELIQKKIREKFAHCTVLTIA 1232
Query: 280 KRTGFVVEHDFIM 242
R +++ D IM
Sbjct: 1233 HRLNTIIDSDKIM 1245
>AF541977-1|AAN17334.1| 1278|Homo sapiens ATP-binding cassette
protein C4 splice variant A protein.
Length = 1278
Score = 46.0 bits (104), Expect = 2e-04
Identities = 45/158 (28%), Positives = 77/158 (48%), Gaps = 9/158 (5%)
Frame = -3
Query: 700 EILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLH--ISYKPQKISPKSQGLVRSLLH 527
E+L ++G G GK++ + + G L P G L +H I+Y Q+ S L ++L
Sbjct: 439 ELLAVVGPVGAGKSSLLSAVLGELAPSHG---LVSVHGRIAYVSQQPWVFSGTLRSNILF 495
Query: 526 DKIRDAYIHPQFLTD--VMKPMKIEEIMDQEV-----QNLSGGELQRVALVLCLGKPADV 368
K + + + + + K +++ E D V LSGG+ RV L + + AD+
Sbjct: 496 GKKYEKERYEKVIKACALKKDLQLLEDGDLTVIGDRGTTLSGGQKARVNLARAVYQDADI 555
Query: 367 YLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEH 254
YL+D+P + +D+E ++ ILH K T +V H
Sbjct: 556 YLLDDPLSAVDAEVSRHLFELCICQILHEKIT-ILVTH 592
Score = 30.3 bits (65), Expect = 8.2
Identities = 46/193 (23%), Positives = 77/193 (39%), Gaps = 25/193 (12%)
Frame = -3
Query: 745 GDFGLRVMPGEFSDSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQ-------LHI 587
G L+ + E + ++G G GK++ I L EP EG + + LH
Sbjct: 1007 GPLVLKHLTALIKSQEKVGIVGRTGAGKSSLISALFRLSEP-EGKIWIDKILTTEIGLHD 1065
Query: 586 SYKPQKISPKSQGLVRSLLHDKIRDAYIHP-----QFLTDVMKPMKIEEI---MDQEV-- 437
K I P+ L + + H L +V IE++ MD E+
Sbjct: 1066 LRKKMSIIPQEPVLFTGTMRKNLDPFNEHTDEELWNALQEVQLKETIEDLPGKMDTELAE 1125
Query: 436 --QNLSGGELQRVALVLCLGKPADVYLIDEPSAYLDSE-QRLVAAKVIKRF-----ILHA 281
N S G+ Q V L + + + +IDE +A +D L+ K+ ++F + A
Sbjct: 1126 SGSNFSVGQRQLVCLARAILRKNQILIIDEATANVDPRTDELIQKKIREKFAHCTVLTIA 1185
Query: 280 KRTGFVVEHDFIM 242
R +++ D IM
Sbjct: 1186 HRLNTIIDSDKIM 1198
>AF071203-1|AAC27077.1| 893|Homo sapiens ABC transporter MOAT-B
isoform protein.
Length = 893
Score = 46.0 bits (104), Expect = 2e-04
Identities = 45/158 (28%), Positives = 77/158 (48%), Gaps = 9/158 (5%)
Frame = -3
Query: 700 EILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLH--ISYKPQKISPKSQGLVRSLLH 527
E+L ++G G GK++ + + G L P G L +H I+Y Q+ S L ++L
Sbjct: 29 ELLAVVGPVGAGKSSLLSAVLGELAPSHG---LVSVHGRIAYVSQQPWVFSGTLRSNILF 85
Query: 526 DKIRDAYIHPQFLTD--VMKPMKIEEIMDQEV-----QNLSGGELQRVALVLCLGKPADV 368
K + + + + + K +++ E D V LSGG+ RV L + + AD+
Sbjct: 86 GKKYEKERYEKVIKACALKKDLQLLEDGDLTVIGDRGTTLSGGQKARVNLARAVYQDADI 145
Query: 367 YLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEH 254
YL+D+P + +D+E ++ ILH K T +V H
Sbjct: 146 YLLDDPLSAVDAEVSRHLFELCICQILHEKIT-ILVTH 182
Score = 30.3 bits (65), Expect = 8.2
Identities = 46/193 (23%), Positives = 77/193 (39%), Gaps = 25/193 (12%)
Frame = -3
Query: 745 GDFGLRVMPGEFSDSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQ-------LHI 587
G L+ + E + ++G G GK++ I L EP EG + + LH
Sbjct: 644 GPLVLKHLTALIKSQEKVGIVGRTGAGKSSLISALFRLSEP-EGKIWIDKILTTEIGLHD 702
Query: 586 SYKPQKISPKSQGLVRSLLHDKIRDAYIHP-----QFLTDVMKPMKIEEI---MDQEV-- 437
K I P+ L + + H L +V IE++ MD E+
Sbjct: 703 LRKKMSIIPQEPVLFTGTMRKNLDPFKEHTDEELWNALQEVQLKETIEDLPGKMDTELAE 762
Query: 436 --QNLSGGELQRVALVLCLGKPADVYLIDEPSAYLDSE-QRLVAAKVIKRF-----ILHA 281
N S G+ Q V L + + + +IDE +A +D L+ K+ ++F + A
Sbjct: 763 SGSNFSVGQRQLVCLARAILRKNQILIIDEATANVDPRTDELIQKKIREKFAHCTVLTIA 822
Query: 280 KRTGFVVEHDFIM 242
R +++ D IM
Sbjct: 823 HRLNTIIDSDKIM 835
>AF071202-1|AAC27076.1| 1325|Homo sapiens ABC transporter MOAT-B
protein.
Length = 1325
Score = 46.0 bits (104), Expect = 2e-04
Identities = 45/158 (28%), Positives = 77/158 (48%), Gaps = 9/158 (5%)
Frame = -3
Query: 700 EILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLH--ISYKPQKISPKSQGLVRSLLH 527
E+L ++G G GK++ + + G L P G L +H I+Y Q+ S L ++L
Sbjct: 439 ELLAVVGPVGAGKSSLLSAVLGELAPSHG---LVSVHGRIAYVSQQPWVFSGTLRSNILF 495
Query: 526 DKIRDAYIHPQFLTD--VMKPMKIEEIMDQEV-----QNLSGGELQRVALVLCLGKPADV 368
K + + + + + K +++ E D V LSGG+ RV L + + AD+
Sbjct: 496 GKKYEKERYEKVIKACALKKDLQLLEDGDLTVIGDRGTTLSGGQKARVNLARAVYQDADI 555
Query: 367 YLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEH 254
YL+D+P + +D+E ++ ILH K T +V H
Sbjct: 556 YLLDDPLSAVDAEVSRHLFELCICQILHEKIT-ILVTH 592
Score = 30.3 bits (65), Expect = 8.2
Identities = 46/193 (23%), Positives = 77/193 (39%), Gaps = 25/193 (12%)
Frame = -3
Query: 745 GDFGLRVMPGEFSDSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQ-------LHI 587
G L+ + E + ++G G GK++ I L EP EG + + LH
Sbjct: 1054 GPLVLKHLTALIKSQEKVGIVGRTGAGKSSLISALFRLSEP-EGKIWIDKILTTEIGLHD 1112
Query: 586 SYKPQKISPKSQGLVRSLLHDKIRDAYIHP-----QFLTDVMKPMKIEEI---MDQEV-- 437
K I P+ L + + H L +V IE++ MD E+
Sbjct: 1113 LRKKMSIIPQEPVLFTGTMRKNLDPFKEHTDEELWNALQEVQLKETIEDLPGKMDTELAE 1172
Query: 436 --QNLSGGELQRVALVLCLGKPADVYLIDEPSAYLDSE-QRLVAAKVIKRF-----ILHA 281
N S G+ Q V L + + + +IDE +A +D L+ K+ ++F + A
Sbjct: 1173 SGSNFSVGQRQLVCLARAILRKNQILIIDEATANVDPRTDELIQKKIREKFAHCTVLTIA 1232
Query: 280 KRTGFVVEHDFIM 242
R +++ D IM
Sbjct: 1233 HRLNTIIDSDKIM 1245
>AB208973-1|BAD92210.1| 776|Homo sapiens ABCC4 protein variant
protein.
Length = 776
Score = 46.0 bits (104), Expect = 2e-04
Identities = 45/158 (28%), Positives = 77/158 (48%), Gaps = 9/158 (5%)
Frame = -3
Query: 700 EILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLH--ISYKPQKISPKSQGLVRSLLH 527
E+L ++G G GK++ + + G L P G L +H I+Y Q+ S L ++L
Sbjct: 356 ELLAVVGPVGAGKSSLLSAVLGELAPSHG---LVSVHGRIAYVSQQPWVFSGTLRSNILF 412
Query: 526 DKIRDAYIHPQFLTD--VMKPMKIEEIMDQEV-----QNLSGGELQRVALVLCLGKPADV 368
K + + + + + K +++ E D V LSGG+ RV L + + AD+
Sbjct: 413 GKEYEKERYEKVIKACALKKDLQLLEDGDLTVIGDRGTTLSGGQKARVNLARAVYQDADI 472
Query: 367 YLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEH 254
YL+D+P + +D+E ++ ILH K T +V H
Sbjct: 473 YLLDDPLSAVDAEVSRHLFELCICQILHEKIT-ILVTH 509
>Y15635-1|CAA75729.1| 2273|Homo sapiens ABCR protein.
Length = 2273
Score = 45.6 bits (103), Expect = 2e-04
Identities = 42/182 (23%), Positives = 83/182 (45%), Gaps = 15/182 (8%)
Frame = -3
Query: 712 FSDSEILVLLGENGTGKTTFIRMLAGNLEPDEGS----GQLPQLHISYKPQKIS--PKSQ 551
F +++I LG NG GKTT + +L G L P G+ G+ + + Q + P+
Sbjct: 953 FYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLVGGRDIETSLDAVRQSLGMCPQHN 1012
Query: 550 GLVRSLLHDKIRDAYIHPQFLTDVMKPMKIEEIMD---------QEVQNLSGGELQRVAL 398
L L + Y + + +++E +++ +E Q+LSGG +++++
Sbjct: 1013 ILFHHLTVAEHMLFYAQLKGKSQEEAQLEMEAMLEDTGLHHKRNEEAQDLSGGMQRKLSV 1072
Query: 397 VLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMATYLADRV 218
+ A V ++DEP++ +D R ++ ++ + RT + H A L DR+
Sbjct: 1073 AIAFVGDAKVVILDEPTSGVDPYSRRSIWDLLLKY--RSGRTIIMSTHHMDEADLLGDRI 1130
Query: 217 IV 212
+
Sbjct: 1131 AI 1132
>M29447-1|AAA59576.1| 1280|Homo sapiens P glycoprotein protein.
Length = 1280
Score = 45.6 bits (103), Expect = 2e-04
Identities = 45/187 (24%), Positives = 84/187 (44%), Gaps = 20/187 (10%)
Frame = -3
Query: 754 KMMGDFGLRVMPGEFSDSEILVLLGENGTGKTTFIRMLAGNLEPDEG----SGQ-LPQLH 590
K++ L+V G+ + L+G +G GK+T ++++ +P EG GQ + ++
Sbjct: 408 KILKGLNLKVQSGQ-----TVALVGNSGCGKSTTVQLMQRLYDPTEGMVSVDGQDIRTIN 462
Query: 589 ISYKPQKISPKSQGLV--------------RSLLHDKIRDAYIHPQFLTDVMK-PMKIEE 455
+ + + I SQ V ++ D+I A +MK P K +
Sbjct: 463 VRFLREIIGVVSQEPVLFATTIAENIRYGRENVTMDEIEKAVKEANAYDFIMKLPHKFDT 522
Query: 454 IMDQEVQNLSGGELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKR 275
++ + LSGG+ QR+A+ L + + L+DE ++ LD+E V + + R
Sbjct: 523 LVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAVVQVALDK--ARKGR 580
Query: 274 TGFVVEH 254
T V+ H
Sbjct: 581 TTIVIAH 587
Score = 41.1 bits (92), Expect = 0.004
Identities = 29/104 (27%), Positives = 52/104 (50%)
Frame = -3
Query: 517 RDAYIHPQFLTDVMKPMKIEEIMDQEVQNLSGGELQRVALVLCLGKPADVYLIDEPSAYL 338
++A IH F+ + P K + + LSGG+ QR+A+ L + + L+DE ++ L
Sbjct: 1150 KEANIHA-FIESL--PNKYSTKVGDKGTQLSGGQKQRIAIARALVRQPHILLLDEATSAL 1206
Query: 337 DSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMATYLADRVIVFE 206
D+E V + + + RT V+ H + AD ++VF+
Sbjct: 1207 DTESEKVVQEALDK--AREGRTCIVIAHR-LSTIQNADLIVVFQ 1247
>M14758-1|AAA59575.1| 1280|Homo sapiens PGY1 protein.
Length = 1280
Score = 45.6 bits (103), Expect = 2e-04
Identities = 45/187 (24%), Positives = 84/187 (44%), Gaps = 20/187 (10%)
Frame = -3
Query: 754 KMMGDFGLRVMPGEFSDSEILVLLGENGTGKTTFIRMLAGNLEPDEG----SGQ-LPQLH 590
K++ L+V G+ + L+G +G GK+T ++++ +P EG GQ + ++
Sbjct: 408 KILKGLNLKVQSGQ-----TVALVGNSGCGKSTTVQLMQRLYDPTEGMVSVDGQDIRTIN 462
Query: 589 ISYKPQKISPKSQGLV--------------RSLLHDKIRDAYIHPQFLTDVMK-PMKIEE 455
+ + + I SQ V ++ D+I A +MK P K +
Sbjct: 463 VRFLREIIGVVSQEPVLFATTIAENIRYGRENVTMDEIEKAVKEANAYDFIMKLPHKFDT 522
Query: 454 IMDQEVQNLSGGELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKR 275
++ + LSGG+ QR+A+ L + + L+DE ++ LD+E V + + R
Sbjct: 523 LVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAVVQVALDK--ARKGR 580
Query: 274 TGFVVEH 254
T V+ H
Sbjct: 581 TTIVIAH 587
Score = 41.1 bits (92), Expect = 0.004
Identities = 29/104 (27%), Positives = 52/104 (50%)
Frame = -3
Query: 517 RDAYIHPQFLTDVMKPMKIEEIMDQEVQNLSGGELQRVALVLCLGKPADVYLIDEPSAYL 338
++A IH F+ + P K + + LSGG+ QR+A+ L + + L+DE ++ L
Sbjct: 1150 KEANIHA-FIESL--PNKYSTKVGDKGTQLSGGQKQRIAIARALVRQPHILLLDEATSAL 1206
Query: 337 DSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMATYLADRVIVFE 206
D+E V + + + RT V+ H + AD ++VF+
Sbjct: 1207 DTESEKVVQEALDK--AREGRTCIVIAHR-LSTIQNADLIVVFQ 1247
>BC130424-1|AAI30425.1| 1280|Homo sapiens ATP-binding cassette,
sub-family B (MDR/TAP), member 1 protein.
Length = 1280
Score = 45.6 bits (103), Expect = 2e-04
Identities = 45/187 (24%), Positives = 84/187 (44%), Gaps = 20/187 (10%)
Frame = -3
Query: 754 KMMGDFGLRVMPGEFSDSEILVLLGENGTGKTTFIRMLAGNLEPDEG----SGQ-LPQLH 590
K++ L+V G+ + L+G +G GK+T ++++ +P EG GQ + ++
Sbjct: 408 KILKGLNLKVQSGQ-----TVALVGNSGCGKSTTVQLMQRLYDPTEGMVSVDGQDIRTIN 462
Query: 589 ISYKPQKISPKSQGLV--------------RSLLHDKIRDAYIHPQFLTDVMK-PMKIEE 455
+ + + I SQ V ++ D+I A +MK P K +
Sbjct: 463 VRFLREIIGVVSQEPVLFATTIAENIRYGRENVTMDEIEKAVKEANAYDFIMKLPHKFDT 522
Query: 454 IMDQEVQNLSGGELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKR 275
++ + LSGG+ QR+A+ L + + L+DE ++ LD+E V + + R
Sbjct: 523 LVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAVVQVALDK--ARKGR 580
Query: 274 TGFVVEH 254
T V+ H
Sbjct: 581 TTIVIAH 587
Score = 41.1 bits (92), Expect = 0.004
Identities = 29/104 (27%), Positives = 52/104 (50%)
Frame = -3
Query: 517 RDAYIHPQFLTDVMKPMKIEEIMDQEVQNLSGGELQRVALVLCLGKPADVYLIDEPSAYL 338
++A IH F+ + P K + + LSGG+ QR+A+ L + + L+DE ++ L
Sbjct: 1150 KEANIHA-FIESL--PNKYSTKVGDKGTQLSGGQKQRIAIARALVRQPHILLLDEATSAL 1206
Query: 337 DSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMATYLADRVIVFE 206
D+E V + + + RT V+ H + AD ++VF+
Sbjct: 1207 DTESEKVVQEALDK--AREGRTCIVIAHR-LSTIQNADLIVVFQ 1247
>AY910577-1|AAW82430.1| 1280|Homo sapiens ATP-binding cassette,
sub-family B (MDR/TAP), member 1 protein.
Length = 1280
Score = 45.6 bits (103), Expect = 2e-04
Identities = 45/187 (24%), Positives = 84/187 (44%), Gaps = 20/187 (10%)
Frame = -3
Query: 754 KMMGDFGLRVMPGEFSDSEILVLLGENGTGKTTFIRMLAGNLEPDEG----SGQ-LPQLH 590
K++ L+V G+ + L+G +G GK+T ++++ +P EG GQ + ++
Sbjct: 408 KILKGLNLKVQSGQ-----TVALVGNSGCGKSTTVQLMQRLYDPTEGMVSVDGQDIRTIN 462
Query: 589 ISYKPQKISPKSQGLV--------------RSLLHDKIRDAYIHPQFLTDVMK-PMKIEE 455
+ + + I SQ V ++ D+I A +MK P K +
Sbjct: 463 VRFLREIIGVVSQEPVLFATTIAENIRYGRENVTMDEIEKAVKEANAYDFIMKLPHKFDT 522
Query: 454 IMDQEVQNLSGGELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKR 275
++ + LSGG+ QR+A+ L + + L+DE ++ LD+E V + + R
Sbjct: 523 LVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAVVQVALDK--ARKGR 580
Query: 274 TGFVVEH 254
T V+ H
Sbjct: 581 TTIVIAH 587
Score = 41.1 bits (92), Expect = 0.004
Identities = 29/104 (27%), Positives = 52/104 (50%)
Frame = -3
Query: 517 RDAYIHPQFLTDVMKPMKIEEIMDQEVQNLSGGELQRVALVLCLGKPADVYLIDEPSAYL 338
++A IH F+ + P K + + LSGG+ QR+A+ L + + L+DE ++ L
Sbjct: 1150 KEANIHA-FIESL--PNKYSTKVGDKGTQLSGGQKQRIAIARALVRQPHILLLDEATSAL 1206
Query: 337 DSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMATYLADRVIVFE 206
D+E V + + + RT V+ H + AD ++VF+
Sbjct: 1207 DTESEKVVQEALDK--AREGRTCIVIAHR-LSTIQNADLIVVFQ 1247
>AF016535-1|AAB69423.1| 1279|Homo sapiens P-glycoprotein protein.
Length = 1279
Score = 45.6 bits (103), Expect = 2e-04
Identities = 45/187 (24%), Positives = 84/187 (44%), Gaps = 20/187 (10%)
Frame = -3
Query: 754 KMMGDFGLRVMPGEFSDSEILVLLGENGTGKTTFIRMLAGNLEPDEG----SGQ-LPQLH 590
K++ L+V G+ + L+G +G GK+T ++++ +P EG GQ + ++
Sbjct: 407 KILKGLNLKVQSGQ-----TVALVGNSGCGKSTTVQLMQRLYDPTEGMVSVDGQDIRTIN 461
Query: 589 ISYKPQKISPKSQGLV--------------RSLLHDKIRDAYIHPQFLTDVMK-PMKIEE 455
+ + + I SQ V ++ D+I A +MK P K +
Sbjct: 462 VRFLREIIGVVSQEPVLFATTIAENIRYGRENVTMDEIEKAVKEANAYDFIMKLPHKFDT 521
Query: 454 IMDQEVQNLSGGELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKR 275
++ + LSGG+ QR+A+ L + + L+DE ++ LD+E V + + R
Sbjct: 522 LVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAVVQVALDK--ARKGR 579
Query: 274 TGFVVEH 254
T V+ H
Sbjct: 580 TTIVIAH 586
Score = 41.1 bits (92), Expect = 0.004
Identities = 29/104 (27%), Positives = 52/104 (50%)
Frame = -3
Query: 517 RDAYIHPQFLTDVMKPMKIEEIMDQEVQNLSGGELQRVALVLCLGKPADVYLIDEPSAYL 338
++A IH F+ + P K + + LSGG+ QR+A+ L + + L+DE ++ L
Sbjct: 1149 KEANIHA-FIESL--PNKYSTKVGDKGTQLSGGQKQRIAIARALVRQPHILLLDEATSAL 1205
Query: 337 DSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMATYLADRVIVFE 206
D+E V + + + RT V+ H + AD ++VF+
Sbjct: 1206 DTESEKVVQEALDK--AREGRTCIVIAHR-LSTIQNADLIVVFQ 1246
>AF001945-1|AAC05632.1| 2273|Homo sapiens rim ABC transporter protein.
Length = 2273
Score = 45.6 bits (103), Expect = 2e-04
Identities = 42/182 (23%), Positives = 83/182 (45%), Gaps = 15/182 (8%)
Frame = -3
Query: 712 FSDSEILVLLGENGTGKTTFIRMLAGNLEPDEGS----GQLPQLHISYKPQKIS--PKSQ 551
F +++I LG NG GKTT + +L G L P G+ G+ + + Q + P+
Sbjct: 953 FYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLVGGRDIETSLDAVRQSLGMCPQHN 1012
Query: 550 GLVRSLLHDKIRDAYIHPQFLTDVMKPMKIEEIMD---------QEVQNLSGGELQRVAL 398
L L + Y + + +++E +++ +E Q+LSGG +++++
Sbjct: 1013 ILFHHLTVAEHMLFYAQLKGKSQEEAQLEMEAMLEDTGLHHKRNEEAQDLSGGMQRKLSV 1072
Query: 397 VLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMATYLADRV 218
+ A V ++DEP++ +D R ++ ++ + RT + H A L DR+
Sbjct: 1073 AIAFVGDAKVVILDEPTSGVDPYSRRSIWDLLLKY--RSGRTIIMSTHHMDEADLLGDRI 1130
Query: 217 IV 212
+
Sbjct: 1131 AI 1132
>AF000148-1|AAC23915.1| 2273|Homo sapiens ATP-binding cassette
transporter protein.
Length = 2273
Score = 45.6 bits (103), Expect = 2e-04
Identities = 42/182 (23%), Positives = 83/182 (45%), Gaps = 15/182 (8%)
Frame = -3
Query: 712 FSDSEILVLLGENGTGKTTFIRMLAGNLEPDEGS----GQLPQLHISYKPQKIS--PKSQ 551
F +++I LG NG GKTT + +L G L P G+ G+ + + Q + P+
Sbjct: 953 FYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLVGGRDIETSLDAVRQSLGMCPQHN 1012
Query: 550 GLVRSLLHDKIRDAYIHPQFLTDVMKPMKIEEIMD---------QEVQNLSGGELQRVAL 398
L L + Y + + +++E +++ +E Q+LSGG +++++
Sbjct: 1013 ILFHHLTVAEHMLFYAQLKGKSQEEAQLEMEAMLEDTGLHHKRNEEAQDLSGGMQRKLSV 1072
Query: 397 VLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMATYLADRV 218
+ A V ++DEP++ +D R ++ ++ + RT + H A L DR+
Sbjct: 1073 AIAFVGDAKVVILDEPTSGVDPYSRRSIWDLLLKY--RSGRTIIMSTHHMDEADLLGDRI 1130
Query: 217 IV 212
+
Sbjct: 1131 AI 1132
>AB210040-1|BAE06122.1| 2303|Homo sapiens ABCA4 variant protein
protein.
Length = 2303
Score = 45.6 bits (103), Expect = 2e-04
Identities = 42/182 (23%), Positives = 83/182 (45%), Gaps = 15/182 (8%)
Frame = -3
Query: 712 FSDSEILVLLGENGTGKTTFIRMLAGNLEPDEGS----GQLPQLHISYKPQKIS--PKSQ 551
F +++I LG NG GKTT + +L G L P G+ G+ + + Q + P+
Sbjct: 983 FYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLVGGRDIETSLDAVRQSLGMCPQHN 1042
Query: 550 GLVRSLLHDKIRDAYIHPQFLTDVMKPMKIEEIMD---------QEVQNLSGGELQRVAL 398
L L + Y + + +++E +++ +E Q+LSGG +++++
Sbjct: 1043 ILFHHLTVAEHMLFYAQLKGKSQEEAQLEMEAMLEDTGLHHKRNEEAQDLSGGMQRKLSV 1102
Query: 397 VLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMATYLADRV 218
+ A V ++DEP++ +D R ++ ++ + RT + H A L DR+
Sbjct: 1103 AIAFVGDAKVVILDEPTSGVDPYSRRSIWDLLLKY--RSGRTIIMSTHHMDEADLLGDRI 1160
Query: 217 IV 212
+
Sbjct: 1161 AI 1162
>AB208970-1|BAD92207.1| 1062|Homo sapiens Multidrug resistance
protein 1 variant protein.
Length = 1062
Score = 45.6 bits (103), Expect = 2e-04
Identities = 45/187 (24%), Positives = 84/187 (44%), Gaps = 20/187 (10%)
Frame = -3
Query: 754 KMMGDFGLRVMPGEFSDSEILVLLGENGTGKTTFIRMLAGNLEPDEG----SGQ-LPQLH 590
K++ L+V G+ + L+G +G GK+T ++++ +P EG GQ + ++
Sbjct: 190 KILKGLNLKVQSGQ-----TVALVGNSGCGKSTTVQLMQRLYDPTEGMVSVDGQDIRTIN 244
Query: 589 ISYKPQKISPKSQGLV--------------RSLLHDKIRDAYIHPQFLTDVMK-PMKIEE 455
+ + + I SQ V ++ D+I A +MK P K +
Sbjct: 245 VRFLREIIGVVSQEPVLFATTIAENIRYGRENVTMDEIEKAVKEANAYDFIMKLPHKFDT 304
Query: 454 IMDQEVQNLSGGELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKR 275
++ + LSGG+ QR+A+ L + + L+DE ++ LD+E V + + R
Sbjct: 305 LVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAVVQVALDK--ARKGR 362
Query: 274 TGFVVEH 254
T V+ H
Sbjct: 363 TTIVIAH 369
Score = 41.1 bits (92), Expect = 0.004
Identities = 29/104 (27%), Positives = 52/104 (50%)
Frame = -3
Query: 517 RDAYIHPQFLTDVMKPMKIEEIMDQEVQNLSGGELQRVALVLCLGKPADVYLIDEPSAYL 338
++A IH F+ + P K + + LSGG+ QR+A+ L + + L+DE ++ L
Sbjct: 932 KEANIHA-FIESL--PNKYSTKVGDKGTQLSGGQKQRIAIARALVRQPHILLLDEATSAL 988
Query: 337 DSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMATYLADRVIVFE 206
D+E V + + + RT V+ H + AD ++VF+
Sbjct: 989 DTESEKVVQEALDK--AREGRTCIVIAHR-LSTIQNADLIVVFQ 1029
>AF136523-1|AAD28285.1| 1321|Homo sapiens bile salt export pump
protein.
Length = 1321
Score = 45.2 bits (102), Expect = 3e-04
Identities = 55/218 (25%), Positives = 99/218 (45%), Gaps = 23/218 (10%)
Frame = -3
Query: 766 PEMXKMMGDFGLRVMPGEFSDSEILVLLGENGTGKTTFIRMLAGNLEPDEG-----SGQL 602
PE+ K++ D + + PGE + L+G +G GK+T ++++ +P EG +
Sbjct: 433 PEV-KILNDLNMAIKPGEMT-----ALVGPSGAGKSTALQLIQRFYDPCEGMVTVDGHDI 486
Query: 601 PQLHISYKPQKISPKSQG--LVRSLLHDKIR----DAYIHP-----------QFLTDVMK 473
L+I + +I Q L + + + IR DA + F+ D+
Sbjct: 487 RSLNIQWLRDQIGIVEQEPVLFSTTIAENIRYGREDATMEDIVQAAKEANAYNFIMDL-- 544
Query: 472 PMKIEEIMDQEVQNLSGGELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRF 293
P + + ++ + +SGG+ QRVA+ L + + L+D ++ LD+E + +V+ +
Sbjct: 545 PQQFDTLVGEGGGQMSGGQKQRVAIARALIRNPKILLLDMATSALDNESEAMVQEVLSK- 603
Query: 292 ILHAKRTGFVVEHDFIMATYLADRVIVFE-GTPSSNAT 182
I H T V H + AD +I FE GT T
Sbjct: 604 IQHG-HTIISVAHR-LSTVRAADTIIGFEHGTAVERGT 639
Score = 37.9 bits (84), Expect = 0.041
Identities = 47/198 (23%), Positives = 85/198 (42%), Gaps = 28/198 (14%)
Frame = -3
Query: 709 SDSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLP-----QLHISYKPQKISPKSQGL 545
S + L +G +G GK+T I++L +PD+G + ++++ + I SQ
Sbjct: 1104 SPGQTLAFVGSSGCGKSTSIQLLERFYDPDQGKVMIDGHDSKKVNVQFLRSNIGIVSQEP 1163
Query: 544 V----------------RSLLHDKIRDAYIHPQFLTDVMK-PMKIEEIMDQEVQNLSGGE 416
V + + +++ A Q VM P K E + + LS GE
Sbjct: 1164 VLFACSIMDNIKYGDNTKEIPMERVIAAAKQAQLHDFVMSLPEKYETNVGSQGSQLSRGE 1223
Query: 415 LQRVALVLCLGKPADVYLIDEPSAYLDSEQR------LVAAKVIKRFILHAKRTGFVVEH 254
QR+A+ + + + L+DE ++ LD+E L A+ + I+ A R +
Sbjct: 1224 KQRIAIARAIVRDPKILLLDEATSALDTESEKTVQVALDKAREGRTCIVIAHRLSTIQNA 1283
Query: 253 DFIMATYLADRVIVFEGT 200
D I +A V++ +GT
Sbjct: 1284 DII--AVMAQGVVIEKGT 1299
>AF078777-1|AAD47141.1| 748|Homo sapiens ABC transporter protein.
Length = 748
Score = 45.2 bits (102), Expect = 3e-04
Identities = 66/261 (25%), Positives = 112/261 (42%), Gaps = 26/261 (9%)
Frame = -3
Query: 736 GLRVMPG---EFSDSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQKI 566
G +V+ G E + + ++G +G+GK+T +R+L EP +GS L +I
Sbjct: 480 GQKVLSGISFEVPAGKKVAIVGGSGSGKSTIVRLLFRFYEPQKGSIYLAGQNIQDVSLVS 539
Query: 565 SPKSQGLVRS---LLHDKIRDAYIH------PQFLTDVMKPMKIEEIM-------DQEVQ 434
++ G+V L H+ I ++ P+ + V K + + + D +V
Sbjct: 540 LRRAVGVVPQDAVLFHNTIYYNLLYGNISASPEEVYAVAKLAGLHDAILRMPHGYDTQVG 599
Query: 433 N----LSGGELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGF 266
LSGGE QRVA+ + K V L DE ++ LDS +K + H RT
Sbjct: 600 ERGLKLSGGEKQRVAIARAILKDPPVILYDEATSSLDSITEETILGAMKDVVKH--RTSI 657
Query: 265 VVEHDFIMATYLADRVIVF-EGTPSSNATAHAPQSLLNGMNKFLELLGITFRRDPNNFRP 89
+ H + AD +IV +G + T H L N + + E+ R N+ P
Sbjct: 658 FIAHR-LSTVVDADEIIVLDQGKVAERGTHHG--LLANPHSIYSEMWHTQSSRVQNHDNP 714
Query: 88 R--INKHASVKDIEQKRAGQD 32
+ K K+ E+K+ ++
Sbjct: 715 KWEAKKENISKEEERKKLQEE 735
>AF328787-1|AAK00959.1| 2146|Homo sapiens ABC transporter member 7
protein.
Length = 2146
Score = 44.8 bits (101), Expect = 4e-04
Identities = 51/192 (26%), Positives = 85/192 (44%), Gaps = 15/192 (7%)
Frame = -3
Query: 733 LRVMPGEFSDSEILVLLGENGTGKTTFIRMLAGNLEPDEGSG-----QLPQLHISYKPQ- 572
LR + +F I LG NG GKTT + +L+G P GS + + +P
Sbjct: 824 LRGLSLDFYQGHITAFLGHNGAGKTTTLSILSGLFPPSGGSAFILGHDVRSSMAAIRPHL 883
Query: 571 KISPKSQGLVRSLLHDKIRDAYIHPQFLT-DVMKPMKIEEIMD------QEVQ--NLSGG 419
+ P+ L L D+ Y + L+ V+ P + + D Q VQ +LSGG
Sbjct: 884 GVCPQYNVLFDMLTVDEHVWFYGRLKGLSAAVVGPEQDRLLQDVGLVSKQSVQTRHLSGG 943
Query: 418 ELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMA 239
+++++ + + V ++DEP+A +D R +++ ++ RT + H A
Sbjct: 944 MQRKLSVAIAFVGGSQVVILDEPTAGVDPASRRGIWELLLKY--REGRTLILSTHHLDEA 1001
Query: 238 TYLADRVIVFEG 203
L DRV V G
Sbjct: 1002 ELLGDRVAVVAG 1013
Score = 34.3 bits (75), Expect = 0.51
Identities = 39/143 (27%), Positives = 61/143 (42%), Gaps = 17/143 (11%)
Frame = -3
Query: 700 EILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQK------ISPKSQGLVR 539
E LLG NG GKT+ RM+ G+ G L ++ +P P+S +
Sbjct: 1821 ECFGLLGVNGAGKTSTFRMVTGDTLASRGEAVLAGHSVAREPSAAHLSMGYCPQSDAIFE 1880
Query: 538 SL-------LHDKIR---DAYIHPQFLTDVMKPMKIEEIMDQEVQNLSGGELQRVALVLC 389
L L ++R +A + Q + + + D+ SGG +++A L
Sbjct: 1881 LLTGREHLELLARLRGVPEAQV-AQTAGSGLARLGLSWYADRPAGTYSGGNKRKLATALA 1939
Query: 388 L-GKPADVYLIDEPSAYLDSEQR 323
L G PA V+L DEP+ +D R
Sbjct: 1940 LVGDPAVVFL-DEPTTGMDPSAR 1961
>AF311102-1|AAN04657.1| 2146|Homo sapiens ABC transporter ABCA7
protein.
Length = 2146
Score = 44.8 bits (101), Expect = 4e-04
Identities = 51/192 (26%), Positives = 85/192 (44%), Gaps = 15/192 (7%)
Frame = -3
Query: 733 LRVMPGEFSDSEILVLLGENGTGKTTFIRMLAGNLEPDEGSG-----QLPQLHISYKPQ- 572
LR + +F I LG NG GKTT + +L+G P GS + + +P
Sbjct: 824 LRGLSLDFYQGHITAFLGHNGAGKTTTLSILSGLFPPSGGSAFILGHDVRSSMAAIRPHL 883
Query: 571 KISPKSQGLVRSLLHDKIRDAYIHPQFLT-DVMKPMKIEEIMD------QEVQ--NLSGG 419
+ P+ L L D+ Y + L+ V+ P + + D Q VQ +LSGG
Sbjct: 884 GVCPQYNVLFDMLTVDEHVWFYGRLKGLSAAVVGPEQDRLLQDVGLVSKQSVQTRHLSGG 943
Query: 418 ELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMA 239
+++++ + + V ++DEP+A +D R +++ ++ RT + H A
Sbjct: 944 MQRKLSVAIAFVGGSQVVILDEPTAGVDPASRRGIWELLLKY--REGRTLILSTHHLDEA 1001
Query: 238 TYLADRVIVFEG 203
L DRV V G
Sbjct: 1002 ELLGDRVAVVAG 1013
Score = 34.3 bits (75), Expect = 0.51
Identities = 39/143 (27%), Positives = 61/143 (42%), Gaps = 17/143 (11%)
Frame = -3
Query: 700 EILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQK------ISPKSQGLVR 539
E LLG NG GKT+ RM+ G+ G L ++ +P P+S +
Sbjct: 1821 ECFGLLGVNGAGKTSTFRMVTGDTLASRGEAVLAGHSVAREPSAAHLSMGYCPQSDAIFE 1880
Query: 538 SL-------LHDKIR---DAYIHPQFLTDVMKPMKIEEIMDQEVQNLSGGELQRVALVLC 389
L L ++R +A + Q + + + D+ SGG +++A L
Sbjct: 1881 LLTGREHLELLARLRGVPEAQV-AQTAGSGLARLGLSWYADRPAGTYSGGNKRKLATALA 1939
Query: 388 L-GKPADVYLIDEPSAYLDSEQR 323
L G PA V+L DEP+ +D R
Sbjct: 1940 LVGDPAVVFL-DEPTTGMDPSAR 1961
>AF250238-1|AAF85794.1| 2146|Homo sapiens macrophage ABC transporter
protein.
Length = 2146
Score = 44.8 bits (101), Expect = 4e-04
Identities = 51/192 (26%), Positives = 85/192 (44%), Gaps = 15/192 (7%)
Frame = -3
Query: 733 LRVMPGEFSDSEILVLLGENGTGKTTFIRMLAGNLEPDEGSG-----QLPQLHISYKPQ- 572
LR + +F I LG NG GKTT + +L+G P GS + + +P
Sbjct: 824 LRGLSLDFYQGHITAFLGHNGAGKTTTLSILSGLFPPSGGSAFILGHDVRSSMAAIRPHL 883
Query: 571 KISPKSQGLVRSLLHDKIRDAYIHPQFLT-DVMKPMKIEEIMD------QEVQ--NLSGG 419
+ P+ L L D+ Y + L+ V+ P + + D Q VQ +LSGG
Sbjct: 884 GVCPQYNVLFDMLTVDEHVWFYGRLKGLSAAVVGPEQDRLLQDVGLVSKQSVQTRHLSGG 943
Query: 418 ELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMA 239
+++++ + + V ++DEP+A +D R +++ ++ RT + H A
Sbjct: 944 MQRKLSVAIAFVGGSQVVILDEPTAGVDPASRRGIWELLLKY--REGRTLILSTHHLDEA 1001
Query: 238 TYLADRVIVFEG 203
L DRV V G
Sbjct: 1002 ELLGDRVAVVAG 1013
Score = 34.3 bits (75), Expect = 0.51
Identities = 39/143 (27%), Positives = 61/143 (42%), Gaps = 17/143 (11%)
Frame = -3
Query: 700 EILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQK------ISPKSQGLVR 539
E LLG NG GKT+ RM+ G+ G L ++ +P P+S +
Sbjct: 1821 ECFGLLGVNGAGKTSTFRMVTGDTLASRGEAVLAGHSVAREPSAAHLSMGYCPQSDAIFE 1880
Query: 538 SL-------LHDKIR---DAYIHPQFLTDVMKPMKIEEIMDQEVQNLSGGELQRVALVLC 389
L L ++R +A + Q + + + D+ SGG +++A L
Sbjct: 1881 LLTGREHLELLARLRGVPEAQV-AQTAGSGLARLGLSWYADRPAGTYSGGNKRKLATALA 1939
Query: 388 L-GKPADVYLIDEPSAYLDSEQR 323
L G PA V+L DEP+ +D R
Sbjct: 1940 LVGDPAVVFL-DEPTTGMDPSAR 1961
>AB055390-1|BAB62294.1| 2008|Homo sapiens ABCA-SSN protein.
Length = 2008
Score = 44.8 bits (101), Expect = 4e-04
Identities = 51/192 (26%), Positives = 85/192 (44%), Gaps = 15/192 (7%)
Frame = -3
Query: 733 LRVMPGEFSDSEILVLLGENGTGKTTFIRMLAGNLEPDEGSG-----QLPQLHISYKPQ- 572
LR + +F I LG NG GKTT + +L+G P GS + + +P
Sbjct: 686 LRGLSLDFYQGHITAFLGHNGAGKTTTLSILSGLFPPSGGSAFILGHDVRSSMAAIRPHL 745
Query: 571 KISPKSQGLVRSLLHDKIRDAYIHPQFLT-DVMKPMKIEEIMD------QEVQ--NLSGG 419
+ P+ L L D+ Y + L+ V+ P + + D Q VQ +LSGG
Sbjct: 746 GVCPQYNVLFDMLTVDEHVWFYGRLKGLSAAVVGPEQDRLLQDVGLVSKQSVQTRHLSGG 805
Query: 418 ELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMA 239
+++++ + + V ++DEP+A +D R +++ ++ RT + H A
Sbjct: 806 MQRKLSVAIAFVGGSQVVILDEPTAGVDPASRRGIWELLLKY--REGRTLILSTHHLDEA 863
Query: 238 TYLADRVIVFEG 203
L DRV V G
Sbjct: 864 ELLGDRVAVVAG 875
Score = 34.3 bits (75), Expect = 0.51
Identities = 39/143 (27%), Positives = 61/143 (42%), Gaps = 17/143 (11%)
Frame = -3
Query: 700 EILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQK------ISPKSQGLVR 539
E LLG NG GKT+ RM+ G+ G L ++ +P P+S +
Sbjct: 1683 ECFGLLGVNGAGKTSTFRMVTGDTLASRGEAVLAGHSVAREPSAAHLSMGYCPQSDAIFE 1742
Query: 538 SL-------LHDKIR---DAYIHPQFLTDVMKPMKIEEIMDQEVQNLSGGELQRVALVLC 389
L L ++R +A + Q + + + D+ SGG +++A L
Sbjct: 1743 LLTGREHLELLARLRGVPEAQV-AQTAGSGLARLGLSWYADRPAGTYSGGNKRKLATALA 1801
Query: 388 L-GKPADVYLIDEPSAYLDSEQR 323
L G PA V+L DEP+ +D R
Sbjct: 1802 LVGDPAVVFL-DEPTTGMDPSAR 1823
>X06181-1|CAA29547.1| 431|Homo sapiens P-glycoprotein (431 AA)
protein.
Length = 431
Score = 44.4 bits (100), Expect = 5e-04
Identities = 31/102 (30%), Positives = 52/102 (50%)
Frame = -3
Query: 511 AYIHPQFLTDVMKPMKIEEIMDQEVQNLSGGELQRVALVLCLGKPADVYLIDEPSAYLDS 332
A IHP F+ + P K E + + LSGG+ QR+A+ L + + L+DE ++ LD+
Sbjct: 303 ANIHP-FIETL--PHKYETRVGDKGTQLSGGQKQRIAIARALIRQPQILLLDEATSALDT 359
Query: 331 EQRLVAAKVIKRFILHAKRTGFVVEHDFIMATYLADRVIVFE 206
E V + + + RT V+ H + AD ++VF+
Sbjct: 360 ESEKVVQEALDK--AREGRTCIVIAHR-LSTIQNADLIVVFQ 398
>U88667-1|AAC51144.1| 2273|Homo sapiens ATP-binding cassette
transporter protein.
Length = 2273
Score = 44.4 bits (100), Expect = 5e-04
Identities = 41/182 (22%), Positives = 83/182 (45%), Gaps = 15/182 (8%)
Frame = -3
Query: 712 FSDSEILVLLGENGTGKTTFIRMLAGNLEPDEGS----GQLPQLHISYKPQKIS--PKSQ 551
F +++I LG NG GKTT + +L G L P G+ G+ + + Q + P+
Sbjct: 953 FYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLVGGRDIETSLDAVRQSLGMCPQHN 1012
Query: 550 GLVRSLLHDKIRDAYIHPQFLTDVMKPMKIEEIMD---------QEVQNLSGGELQRVAL 398
L L + Y + + +++E +++ +E Q+LSGG +++++
Sbjct: 1013 ILFHHLTVAEHMLFYAQLKGKSQEEAQLEMEAMLEDTGLHHKRNEEAQDLSGGMQRKLSV 1072
Query: 397 VLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMATYLADRV 218
+ A V ++DEP++ +D R ++ ++ + RT + H A + DR+
Sbjct: 1073 AIAFVGDAKVVILDEPTSGVDPYSRRSIWDLLLKY--RSGRTIIMPTHHMDEADHQGDRI 1130
Query: 217 IV 212
+
Sbjct: 1131 AI 1132
>BC041091-1|AAH41091.1| 646|Homo sapiens ATP-binding cassette,
sub-family G (WHITE), member 4 protein.
Length = 646
Score = 44.4 bits (100), Expect = 5e-04
Identities = 39/164 (23%), Positives = 76/164 (46%), Gaps = 19/164 (11%)
Frame = -3
Query: 733 LRVMPGEFSDSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQKISP-- 560
L+ + G+F E++ ++G +G GK+TF+ +LAG E SG Q+ ++ +P+++
Sbjct: 85 LKCLSGKFCRRELIGIMGPSGAGKSTFMNILAGYRE----SGMKGQILVNGRPRELRTFR 140
Query: 559 KSQGLVRS----LLHDKIRDAY-------------IHPQFLTDVMKPMKIEEIMDQEVQN 431
K + L H + +A + + +T+++ + +
Sbjct: 141 KMSCYIMQDDMLLPHLTVLEAMMVSANLKLSEKQEVKKELVTEILTALGLMSCSHTRTAL 200
Query: 430 LSGGELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIK 299
LSGG+ +R+A+ L L V DEP++ LDS ++K
Sbjct: 201 LSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMK 244
>AJ308237-1|CAC87131.1| 646|Homo sapiens ABC transporter protein.
Length = 646
Score = 44.4 bits (100), Expect = 5e-04
Identities = 39/164 (23%), Positives = 76/164 (46%), Gaps = 19/164 (11%)
Frame = -3
Query: 733 LRVMPGEFSDSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQKISP-- 560
L+ + G+F E++ ++G +G GK+TF+ +LAG E SG Q+ ++ +P+++
Sbjct: 85 LKCLSGKFCRRELIGIMGPSGAGKSTFMNILAGYRE----SGMKGQILVNGRPRELRTFR 140
Query: 559 KSQGLVRS----LLHDKIRDAY-------------IHPQFLTDVMKPMKIEEIMDQEVQN 431
K + L H + +A + + +T+++ + +
Sbjct: 141 KMSCYIMQDDMLLPHLTVLEAMMVSANLKLSEKQEVKKELVTEILTALGLMSCSHTRTAL 200
Query: 430 LSGGELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIK 299
LSGG+ +R+A+ L L V DEP++ LDS ++K
Sbjct: 201 LSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMK 244
>AJ300465-1|CAC17140.1| 627|Homo sapiens putative white family
ATP-binding cassette transporter protein.
Length = 627
Score = 44.4 bits (100), Expect = 5e-04
Identities = 39/164 (23%), Positives = 76/164 (46%), Gaps = 19/164 (11%)
Frame = -3
Query: 733 LRVMPGEFSDSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQKISP-- 560
L+ + G+F E++ ++G +G GK+TF+ +LAG E SG Q+ ++ +P+++
Sbjct: 66 LKCLSGKFCRRELIGIMGPSGAGKSTFMNILAGYRE----SGMKGQILVNGRPRELRTFR 121
Query: 559 KSQGLVRS----LLHDKIRDAY-------------IHPQFLTDVMKPMKIEEIMDQEVQN 431
K + L H + +A + + +T+++ + +
Sbjct: 122 KMSCYIMQDDMLLPHLTVLEAMMVSANLKLSEKQEVKKELVTEILTALGLMSCSHTRTAL 181
Query: 430 LSGGELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIK 299
LSGG+ +R+A+ L L V DEP++ LDS ++K
Sbjct: 182 LSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMK 225
>AF091582-1|AAC77455.1| 1321|Homo sapiens bile salt export pump
protein.
Length = 1321
Score = 44.4 bits (100), Expect = 5e-04
Identities = 55/218 (25%), Positives = 99/218 (45%), Gaps = 23/218 (10%)
Frame = -3
Query: 766 PEMXKMMGDFGLRVMPGEFSDSEILVLLGENGTGKTTFIRMLAGNLEPDEG-----SGQL 602
PE+ K++ D + + PGE + L+G +G GK+T ++++ +P EG +
Sbjct: 433 PEV-KILNDLNMVIKPGEMT-----ALVGPSGAGKSTALQLIQRFYDPCEGMVTVDGHDI 486
Query: 601 PQLHISYKPQKISPKSQG--LVRSLLHDKIR----DAYIHP-----------QFLTDVMK 473
L+I + +I Q L + + + IR DA + F+ D+
Sbjct: 487 RSLNIQWLRDQIGIVEQEPVLFSTTIAENIRYGREDATMEDIVQAAKEANAYNFIMDL-- 544
Query: 472 PMKIEEIMDQEVQNLSGGELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRF 293
P + + ++ + +SGG+ QRVA+ L + + L+D ++ LD+E + +V+ +
Sbjct: 545 PQQFDTLVGEGGGQMSGGQKQRVAIARALIRNPKILLLDMATSALDNESEAMVQEVLSK- 603
Query: 292 ILHAKRTGFVVEHDFIMATYLADRVIVFE-GTPSSNAT 182
I H T V H + AD +I FE GT T
Sbjct: 604 IQHG-HTIISVAHR-LSTVRAADTIIGFEHGTAVERGT 639
Score = 37.9 bits (84), Expect = 0.041
Identities = 47/198 (23%), Positives = 85/198 (42%), Gaps = 28/198 (14%)
Frame = -3
Query: 709 SDSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLP-----QLHISYKPQKISPKSQGL 545
S + L +G +G GK+T I++L +PD+G + ++++ + I SQ
Sbjct: 1104 SPGQTLAFVGSSGCGKSTSIQLLERFYDPDQGKVMIDGHDSKKVNVQFLRSNIGIVSQEP 1163
Query: 544 V----------------RSLLHDKIRDAYIHPQFLTDVMK-PMKIEEIMDQEVQNLSGGE 416
V + + +++ A Q VM P K E + + LS GE
Sbjct: 1164 VLFACSIMDNIKYGDNTKEIPMERVIAAAKQAQLHDFVMSLPEKYETNVGSQGSQLSRGE 1223
Query: 415 LQRVALVLCLGKPADVYLIDEPSAYLDSEQR------LVAAKVIKRFILHAKRTGFVVEH 254
QR+A+ + + + L+DE ++ LD+E L A+ + I+ A R +
Sbjct: 1224 KQRIAIARAIVRDPKILLLDEATSALDTESEKTVQVALDKAREGRTCIVIAHRLSTIQNA 1283
Query: 253 DFIMATYLADRVIVFEGT 200
D I +A V++ +GT
Sbjct: 1284 DII--AVMAQGVVIEKGT 1299
>AC008177-1|AAY24305.1| 870|Homo sapiens unknown protein.
Length = 870
Score = 44.4 bits (100), Expect = 5e-04
Identities = 55/218 (25%), Positives = 99/218 (45%), Gaps = 23/218 (10%)
Frame = -3
Query: 766 PEMXKMMGDFGLRVMPGEFSDSEILVLLGENGTGKTTFIRMLAGNLEPDEG-----SGQL 602
PE+ K++ D + + PGE + L+G +G GK+T ++++ +P EG +
Sbjct: 433 PEV-KILNDLNMVIKPGEMT-----ALVGPSGAGKSTALQLIQRFYDPCEGMVTVDGHDI 486
Query: 601 PQLHISYKPQKISPKSQG--LVRSLLHDKIR----DAYIHP-----------QFLTDVMK 473
L+I + +I Q L + + + IR DA + F+ D+
Sbjct: 487 RSLNIQWLRDQIGIVEQEPVLFSTTIAENIRYGREDATMEDIVQAAKEANAYNFIMDL-- 544
Query: 472 PMKIEEIMDQEVQNLSGGELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRF 293
P + + ++ + +SGG+ QRVA+ L + + L+D ++ LD+E + +V+ +
Sbjct: 545 PQQFDTLVGEGGGQMSGGQKQRVAIARALIRNPKILLLDMATSALDNESEAMVQEVLSK- 603
Query: 292 ILHAKRTGFVVEHDFIMATYLADRVIVFE-GTPSSNAT 182
I H T V H + AD +I FE GT T
Sbjct: 604 IQHG-HTIISVAHR-LSTVRAADTIIGFEHGTAVERGT 639
>AK172812-1|BAD18782.1| 571|Homo sapiens protein ( Homo sapiens
cDNA FLJ23973 fis, clone HEP18305, highly similar to
ATP-binding cassette, sub-family B, member 6,
mitochondrial precursor. ).
Length = 571
Score = 44.0 bits (99), Expect = 6e-04
Identities = 54/209 (25%), Positives = 89/209 (42%), Gaps = 21/209 (10%)
Frame = -3
Query: 769 YPEMXKMMGDFGLRVMPGEFSDSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLH 590
Y + + + D VMP + L L+G +G GK+T +R+L + G ++
Sbjct: 328 YADGRETLQDVSFTVMP-----EQTLALVGPSGAGKSTILRLLFLFYDISSGCIRIDGQD 382
Query: 589 ISYKPQK-------ISPKSQGLVRSLLHDKIR-----------DAYIHPQFLTDVMK--P 470
IS Q + P+ L + D IR +A + D + P
Sbjct: 383 ISQVTQASLRSHIGVVPQDTVLFNDTIADNIRYGRVTAGNDEVEAAAQAAGIHDAIMAFP 442
Query: 469 MKIEEIMDQEVQNLSGGELQRVALVLCLGKPADVYLIDEPSAYLD-SEQRLVAAKVIKRF 293
+ + LSGGE QRVA+ + K + L+DE ++ LD S +R + A + K
Sbjct: 443 EGYRTQVGERGLKLSGGEKQRVAIARTILKAPGIILLDEATSALDTSNERAIQASLAK-- 500
Query: 292 ILHAKRTGFVVEHDFIMATYLADRVIVFE 206
+ A RT VV H + AD+++V +
Sbjct: 501 -VCANRTTIVVAHR-LSTVVNADQILVIK 527
>BC051884-1|AAH51884.2| 709|Homo sapiens ATP-binding cassette,
sub-family F (GCN20), member 3 protein.
Length = 709
Score = 43.2 bits (97), Expect = 0.001
Identities = 35/141 (24%), Positives = 63/141 (44%), Gaps = 7/141 (4%)
Frame = -3
Query: 694 LVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQ-LHISYKPQ------KISPKSQGLVRS 536
+ ++GENG GK+T +++L G+L P G + L I Y Q ++ + L+
Sbjct: 521 ICVVGENGAGKSTMLKLLLGDLAPVRGIRHAHRNLKIGYFSQHHVEQLDLNVSAVELLAR 580
Query: 535 LLHDKIRDAYIHPQFLTDVMKPMKIEEIMDQEVQNLSGGELQRVALVLCLGKPADVYLID 356
+ + Y H + E+ + + +LSGG+ RVA + Y++D
Sbjct: 581 KFPGRPEEEYRHQLGRYGIS-----GELAMRPLASLSGGQKSRVAFAQMTMPCPNFYILD 635
Query: 355 EPSAYLDSEQRLVAAKVIKRF 293
EP+ +LD E + + F
Sbjct: 636 EPTNHLDMETIEALGRALNNF 656
Score = 31.1 bits (67), Expect = 4.7
Identities = 23/81 (28%), Positives = 37/81 (45%)
Frame = -3
Query: 457 EIMDQEVQNLSGGELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAK 278
++ Q + SGG R+AL L D+ L+DEP+ LD + A ++ ++
Sbjct: 319 KMQQQPTREFSGGWRMRLALARALFARPDLLLLDEPTNMLD----VRAILWLENYLQTWP 374
Query: 277 RTGFVVEHDFIMATYLADRVI 215
T VV HD +A +I
Sbjct: 375 STILVVSHDRNFLNAIATDII 395
>BC051754-1|AAH51754.1| 709|Homo sapiens ATP-binding cassette,
sub-family F (GCN20), member 3 protein.
Length = 709
Score = 43.2 bits (97), Expect = 0.001
Identities = 35/141 (24%), Positives = 63/141 (44%), Gaps = 7/141 (4%)
Frame = -3
Query: 694 LVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQ-LHISYKPQ------KISPKSQGLVRS 536
+ ++GENG GK+T +++L G+L P G + L I Y Q ++ + L+
Sbjct: 521 ICVVGENGAGKSTMLKLLLGDLAPVRGIRHAHRNLKIGYFSQHHVEQLDLNVSAVELLAR 580
Query: 535 LLHDKIRDAYIHPQFLTDVMKPMKIEEIMDQEVQNLSGGELQRVALVLCLGKPADVYLID 356
+ + Y H + E+ + + +LSGG+ RVA + Y++D
Sbjct: 581 KFPGRPEEEYRHQLGRYGIS-----GELAMRPLASLSGGQKSRVAFAQMTMPCPNFYILD 635
Query: 355 EPSAYLDSEQRLVAAKVIKRF 293
EP+ +LD E + + F
Sbjct: 636 EPTNHLDMETIEALGRALNNF 656
Score = 31.1 bits (67), Expect = 4.7
Identities = 23/81 (28%), Positives = 37/81 (45%)
Frame = -3
Query: 457 EIMDQEVQNLSGGELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAK 278
++ Q + SGG R+AL L D+ L+DEP+ LD + A ++ ++
Sbjct: 319 KMQQQPTREFSGGWRMRLALARALFARPDLLLLDEPTNMLD----VRAILWLENYLQTWP 374
Query: 277 RTGFVVEHDFIMATYLADRVI 215
T VV HD +A +I
Sbjct: 375 STILVVSHDRNFLNAIATDII 395
>BC009253-1|AAH09253.1| 709|Homo sapiens ATP-binding cassette,
sub-family F (GCN20), member 3 protein.
Length = 709
Score = 43.2 bits (97), Expect = 0.001
Identities = 35/141 (24%), Positives = 63/141 (44%), Gaps = 7/141 (4%)
Frame = -3
Query: 694 LVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQ-LHISYKPQ------KISPKSQGLVRS 536
+ ++GENG GK+T +++L G+L P G + L I Y Q ++ + L+
Sbjct: 521 ICVVGENGAGKSTMLKLLLGDLAPVRGIRHAHRNLKIGYFSQHHVEQLDLNVSAVELLAR 580
Query: 535 LLHDKIRDAYIHPQFLTDVMKPMKIEEIMDQEVQNLSGGELQRVALVLCLGKPADVYLID 356
+ + Y H + E+ + + +LSGG+ RVA + Y++D
Sbjct: 581 KFPGRPEEEYRHQLGRYGIS-----GELAMRPLASLSGGQKSRVAFAQMTMPCPNFYILD 635
Query: 355 EPSAYLDSEQRLVAAKVIKRF 293
EP+ +LD E + + F
Sbjct: 636 EPTNHLDMETIEALGRALNNF 656
Score = 31.1 bits (67), Expect = 4.7
Identities = 23/81 (28%), Positives = 37/81 (45%)
Frame = -3
Query: 457 EIMDQEVQNLSGGELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAK 278
++ Q + SGG R+AL L D+ L+DEP+ LD + A ++ ++
Sbjct: 319 KMQQQPTREFSGGWRMRLALARALFARPDLLLLDEPTNMLD----VRAILWLENYLQTWP 374
Query: 277 RTGFVVEHDFIMATYLADRVI 215
T VV HD +A +I
Sbjct: 375 STILVVSHDRNFLNAIATDII 395
>AY040219-1|AAK76739.1| 1382|Homo sapiens ATP-binding cassette
transporter sub-family C member 11 protein.
Length = 1382
Score = 43.2 bits (97), Expect = 0.001
Identities = 45/202 (22%), Positives = 95/202 (47%), Gaps = 8/202 (3%)
Frame = -3
Query: 709 SDSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQKISPKSQGLVRSLL 530
S +L + G G+GK++ + + + EGS + Q ++Y PQ+ S + ++L
Sbjct: 535 SKGMMLGVCGNTGSGKSSLLSAILEEMHLLEGSVGV-QGSLAYVPQQAWIVSGNIRENIL 593
Query: 529 ----HDKIRDAYI-HPQFLTDVMKPMKIEEIMD--QEVQNLSGGELQRVALVLCLGKPAD 371
+DK R + H L ++ + ++ + + NLSGG+ QR++L +
Sbjct: 594 MGGAYDKARYLQVLHCCSLNRDLELLPFGDMTEIGERGLNLSGGQKQRISLARAVYSDRQ 653
Query: 370 VYLIDEPSAYLDSE-QRLVAAKVIKRFILHAKRTGFVVEHDFIMATYLADRVIVFEGTPS 194
+YL+D+P + +D+ + + + IK+ + +T +V H + +++ G
Sbjct: 654 IYLLDDPLSAVDAHVGKHIFEECIKKTL--RGKTVVLVTHQLQYLEFCGQIILLENGKIC 711
Query: 193 SNATAHAPQSLLNGMNKFLELL 128
N T H+ L+ K+ +L+
Sbjct: 712 ENGT-HS--ELMQKKGKYAQLI 730
>AL807752-22|CAI12768.1| 2435|Homo sapiens ATP-binding cassette,
sub-family A (ABC1), membertor protein.
Length = 2435
Score = 43.2 bits (97), Expect = 0.001
Identities = 48/183 (26%), Positives = 84/183 (45%), Gaps = 18/183 (9%)
Frame = -3
Query: 706 DSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQKISPKSQGLV--RSL 533
+++++ LG NG GKTT + +L G P GS + I + +I K+ G+ ++
Sbjct: 1016 ENQVVSFLGHNGAGKTTTMSILTGLFPPTSGSATIYGHDIRTEMDEIR-KNLGMCPQHNV 1074
Query: 532 LHDKIRDAYIHPQFLTDVMKPMKIEEI---MDQE-------------VQNLSGGELQRVA 401
L D++ H F + +K M EEI MD+ VQ LSGG ++++
Sbjct: 1075 LFDRL-TVEEHLWFYSR-LKSMAQEEIRREMDKMIEDLELSNKRHSLVQTLSGGMKRKLS 1132
Query: 400 LVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMATYLADR 221
+ + + ++DEP+A +D R +I ++ RT + H A L DR
Sbjct: 1133 VAIAFVGGSRAIILDEPTAGVDPYARRAIWDLILKY--KPGRTILLSTHHMDEADLLGDR 1190
Query: 220 VIV 212
+ +
Sbjct: 1191 IAI 1193
>AK092415-1|BAC03881.1| 703|Homo sapiens protein ( Homo sapiens
cDNA FLJ35096 fis, clone PLACE6006217, weakly similar to
GCN20 PROTEIN. ).
Length = 703
Score = 43.2 bits (97), Expect = 0.001
Identities = 35/141 (24%), Positives = 63/141 (44%), Gaps = 7/141 (4%)
Frame = -3
Query: 694 LVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQ-LHISYKPQ------KISPKSQGLVRS 536
+ ++GENG GK+T +++L G+L P G + L I Y Q ++ + L+
Sbjct: 515 ICVVGENGAGKSTMLKLLLGDLAPVRGIRHAHRNLKIGYFSQHHVEQLDLNVSAVELLAR 574
Query: 535 LLHDKIRDAYIHPQFLTDVMKPMKIEEIMDQEVQNLSGGELQRVALVLCLGKPADVYLID 356
+ + Y H + E+ + + +LSGG+ RVA + Y++D
Sbjct: 575 KFPGRPEEEYRHQLGRYGIS-----GELAMRPLASLSGGQKSRVAFAQMTMPCPNFYILD 629
Query: 355 EPSAYLDSEQRLVAAKVIKRF 293
EP+ +LD E + + F
Sbjct: 630 EPTNHLDMETIEALGRALNNF 650
Score = 31.1 bits (67), Expect = 4.7
Identities = 23/81 (28%), Positives = 37/81 (45%)
Frame = -3
Query: 457 EIMDQEVQNLSGGELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAK 278
++ Q + SGG R+AL L D+ L+DEP+ LD + A ++ ++
Sbjct: 313 KMQQQPTREFSGGWRMRLALARALFARPDLLLLDEPTNMLD----VRAILWLENYLQTWP 368
Query: 277 RTGFVVEHDFIMATYLADRVI 215
T VV HD +A +I
Sbjct: 369 STILVVSHDRNFLNAIATDII 389
>AK024758-1|BAB14989.1| 390|Homo sapiens protein ( Homo sapiens
cDNA: FLJ21105 fis, clone CAS05114. ).
Length = 390
Score = 43.2 bits (97), Expect = 0.001
Identities = 35/141 (24%), Positives = 63/141 (44%), Gaps = 7/141 (4%)
Frame = -3
Query: 694 LVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQ-LHISYKPQ------KISPKSQGLVRS 536
+ ++GENG GK+T +++L G+L P G + L I Y Q ++ + L+
Sbjct: 202 ICVVGENGAGKSTMLKLLLGDLAPVRGIRHAHRNLKIGYFSQHHVEQLDLNVSAVELLAR 261
Query: 535 LLHDKIRDAYIHPQFLTDVMKPMKIEEIMDQEVQNLSGGELQRVALVLCLGKPADVYLID 356
+ + Y H + E+ + + +LSGG+ RVA + Y++D
Sbjct: 262 KFPGRPEEEYRHQLGRYGIS-----GELAMRPLASLSGGQKSRVAFAQMTMPCPNFYILD 316
Query: 355 EPSAYLDSEQRLVAAKVIKRF 293
EP+ +LD E + + F
Sbjct: 317 EPTNHLDMETIEALGRALNNF 337
Score = 30.7 bits (66), Expect = 6.2
Identities = 23/80 (28%), Positives = 36/80 (45%)
Frame = -3
Query: 454 IMDQEVQNLSGGELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKR 275
+ Q + SGG R+AL L D+ L+DEP+ LD + A ++ ++
Sbjct: 1 MQQQPTREFSGGWRMRLALARALFARPDLLLLDEPTNMLD----VRAILWLENYLQTWPS 56
Query: 274 TGFVVEHDFIMATYLADRVI 215
T VV HD +A +I
Sbjct: 57 TILVVSHDRNFLNAIATDII 76
>AK002060-1|BAA92063.1| 709|Homo sapiens protein ( Homo sapiens
cDNA FLJ11198 fis, clone PLACE1007697, weakly similar to
GCN20 PROTEIN. ).
Length = 709
Score = 43.2 bits (97), Expect = 0.001
Identities = 35/141 (24%), Positives = 63/141 (44%), Gaps = 7/141 (4%)
Frame = -3
Query: 694 LVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQ-LHISYKPQ------KISPKSQGLVRS 536
+ ++GENG GK+T +++L G+L P G + L I Y Q ++ + L+
Sbjct: 521 ICVVGENGAGKSTMLKLLLGDLAPVRGIRHAHRNLKIGYFSQHHVEQLDLNVSAVELLAR 580
Query: 535 LLHDKIRDAYIHPQFLTDVMKPMKIEEIMDQEVQNLSGGELQRVALVLCLGKPADVYLID 356
+ + Y H + E+ + + +LSGG+ RVA + Y++D
Sbjct: 581 KFPGRPEEEYRHQLGRYGIS-----GELAMRPLASLSGGQKSRVAFAQMTMPCPNFYILD 635
Query: 355 EPSAYLDSEQRLVAAKVIKRF 293
EP+ +LD E + + F
Sbjct: 636 EPTNHLDMETIEALGRALNNF 656
Score = 31.1 bits (67), Expect = 4.7
Identities = 23/81 (28%), Positives = 37/81 (45%)
Frame = -3
Query: 457 EIMDQEVQNLSGGELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAK 278
++ Q + SGG R+AL L D+ L+DEP+ LD + A ++ ++
Sbjct: 319 KMQQQPTREFSGGWRMRLALARALFARPDLLLLDEPTNMLD----VRAILWLENYLQTWP 374
Query: 277 RTGFVVEHDFIMATYLADRVI 215
T VV HD +A +I
Sbjct: 375 STILVVSHDRNFLNAIATDII 395
>AF411579-1|AAL99902.1| 1344|Homo sapiens ATP-binding cassette protein
C11 isoform A protein.
Length = 1344
Score = 43.2 bits (97), Expect = 0.001
Identities = 45/202 (22%), Positives = 95/202 (47%), Gaps = 8/202 (3%)
Frame = -3
Query: 709 SDSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQKISPKSQGLVRSLL 530
S +L + G G+GK++ + + + EGS + Q ++Y PQ+ S + ++L
Sbjct: 535 SKGMMLGVCGNTGSGKSSLLSAILEEMHLLEGSVGV-QGSLAYVPQQAWIVSGNIRENIL 593
Query: 529 ----HDKIRDAYI-HPQFLTDVMKPMKIEEIMD--QEVQNLSGGELQRVALVLCLGKPAD 371
+DK R + H L ++ + ++ + + NLSGG+ QR++L +
Sbjct: 594 MGGAYDKARYLQVLHCCSLNRDLELLPFGDMTEIGERGLNLSGGQKQRISLARAVYSDRQ 653
Query: 370 VYLIDEPSAYLDSE-QRLVAAKVIKRFILHAKRTGFVVEHDFIMATYLADRVIVFEGTPS 194
+YL+D+P + +D+ + + + IK+ + +T +V H + +++ G
Sbjct: 654 IYLLDDPLSAVDAHVGKHIFEECIKKTL--RGKTVVLVTHQLQYLEFCGQIILLENGKIC 711
Query: 193 SNATAHAPQSLLNGMNKFLELL 128
N T H+ L+ K+ +L+
Sbjct: 712 ENGT-HS--ELMQKKGKYAQLI 730
>AF367202-1|AAK58869.1| 1382|Homo sapiens ATP-binding cassette protein
C11 protein.
Length = 1382
Score = 43.2 bits (97), Expect = 0.001
Identities = 45/202 (22%), Positives = 95/202 (47%), Gaps = 8/202 (3%)
Frame = -3
Query: 709 SDSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQKISPKSQGLVRSLL 530
S +L + G G+GK++ + + + EGS + Q ++Y PQ+ S + ++L
Sbjct: 535 SKGMMLGVCGNTGSGKSSLLSAILEEMHLLEGSVGV-QGSLAYVPQQAWIVSGNIRENIL 593
Query: 529 ----HDKIRDAYI-HPQFLTDVMKPMKIEEIMD--QEVQNLSGGELQRVALVLCLGKPAD 371
+DK R + H L ++ + ++ + + NLSGG+ QR++L +
Sbjct: 594 MGGAYDKARYLQVLHCCSLNRDLELLPFGDMTEIGERGLNLSGGQKQRISLARAVYSDRQ 653
Query: 370 VYLIDEPSAYLDSE-QRLVAAKVIKRFILHAKRTGFVVEHDFIMATYLADRVIVFEGTPS 194
+YL+D+P + +D+ + + + IK+ + +T +V H + +++ G
Sbjct: 654 IYLLDDPLSAVDAHVGKHIFEECIKKTL--RGKTVVLVTHQLQYLEFCGQIILLENGKIC 711
Query: 193 SNATAHAPQSLLNGMNKFLELL 128
N T H+ L+ K+ +L+
Sbjct: 712 ENGT-HS--ELMQKKGKYAQLI 730
>AF327705-1|AAK14335.1| 2436|Homo sapiens ABC transporter ABCA2
protein.
Length = 2436
Score = 43.2 bits (97), Expect = 0.001
Identities = 48/183 (26%), Positives = 84/183 (45%), Gaps = 18/183 (9%)
Frame = -3
Query: 706 DSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQKISPKSQGLV--RSL 533
+++++ LG NG GKTT + +L G P GS + I + +I K+ G+ ++
Sbjct: 1017 ENQVVSFLGHNGAGKTTTMSILTGLFPPTSGSATIYGHDIRTEMDEIR-KNLGMCPQHNV 1075
Query: 532 LHDKIRDAYIHPQFLTDVMKPMKIEEI---MDQE-------------VQNLSGGELQRVA 401
L D++ H F + +K M EEI MD+ VQ LSGG ++++
Sbjct: 1076 LFDRL-TVEEHLWFYSR-LKSMAQEEIRREMDKMIEDLELSNKRHSLVQTLSGGMKRKLS 1133
Query: 400 LVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMATYLADR 221
+ + + ++DEP+A +D R +I ++ RT + H A L DR
Sbjct: 1134 VAIAFVGGSRAIILDEPTAGVDPYARRAIWDLILKY--KPGRTILLSTHHMDEADLLGDR 1191
Query: 220 VIV 212
+ +
Sbjct: 1192 IAI 1194
>AF327657-1|AAK14334.1| 2436|Homo sapiens ABC transporter ABCA2
protein.
Length = 2436
Score = 43.2 bits (97), Expect = 0.001
Identities = 48/183 (26%), Positives = 84/183 (45%), Gaps = 18/183 (9%)
Frame = -3
Query: 706 DSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQKISPKSQGLV--RSL 533
+++++ LG NG GKTT + +L G P GS + I + +I K+ G+ ++
Sbjct: 1017 ENQVVSFLGHNGAGKTTTMSILTGLFPPTSGSATIYGHDIRTEMDEIR-KNLGMCPQHNV 1075
Query: 532 LHDKIRDAYIHPQFLTDVMKPMKIEEI---MDQE-------------VQNLSGGELQRVA 401
L D++ H F + +K M EEI MD+ VQ LSGG ++++
Sbjct: 1076 LFDRL-TVEEHLWFYSR-LKSMAQEEIRREMDKMIEDLELSNKRHSLVQTLSGGMKRKLS 1133
Query: 400 LVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMATYLADR 221
+ + + ++DEP+A +D R +I ++ RT + H A L DR
Sbjct: 1134 VAIAFVGGSRAIILDEPTAGVDPYARRAIWDLILKY--KPGRTILLSTHHMDEADLLGDR 1191
Query: 220 VIV 212
+ +
Sbjct: 1192 IAI 1194
>AF178941-1|AAG09372.1| 2436|Homo sapiens ATP-binding cassette
sub-family A member 2 protein.
Length = 2436
Score = 43.2 bits (97), Expect = 0.001
Identities = 48/183 (26%), Positives = 84/183 (45%), Gaps = 18/183 (9%)
Frame = -3
Query: 706 DSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQKISPKSQGLV--RSL 533
+++++ LG NG GKTT + +L G P GS + I + +I K+ G+ ++
Sbjct: 1017 ENQVVSFLGHNGAGKTTTMSILTGLFPPTSGSATIYGHDIRTEMDEIR-KNLGMCPQHNV 1075
Query: 532 LHDKIRDAYIHPQFLTDVMKPMKIEEI---MDQE-------------VQNLSGGELQRVA 401
L D++ H F + +K M EEI MD+ VQ LSGG ++++
Sbjct: 1076 LFDRL-TVEEHLWFYSR-LKSMAQEEIRREMDKMIEDLELSNKRHSLVQTLSGGMKRKLS 1133
Query: 400 LVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMATYLADR 221
+ + + ++DEP+A +D R +I ++ RT + H A L DR
Sbjct: 1134 VAIAFVGGSRAIILDEPTAGVDPYARRAIWDLILKY--KPGRTILLSTHHMDEADLLGDR 1191
Query: 220 VIV 212
+ +
Sbjct: 1192 IAI 1194
>AB177854-1|BAD66832.1| 1440|Homo sapiens KIAA1062 splice variant 1
protein.
Length = 1440
Score = 43.2 bits (97), Expect = 0.001
Identities = 48/183 (26%), Positives = 84/183 (45%), Gaps = 18/183 (9%)
Frame = -3
Query: 706 DSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQKISPKSQGLV--RSL 533
+++++ LG NG GKTT + +L G P GS + I + +I K+ G+ ++
Sbjct: 366 ENQVVSFLGHNGAGKTTTMSILTGLFPPTSGSATIYGHDIRTEMDEIR-KNLGMCPQHNV 424
Query: 532 LHDKIRDAYIHPQFLTDVMKPMKIEEI---MDQE-------------VQNLSGGELQRVA 401
L D++ H F + +K M EEI MD+ VQ LSGG ++++
Sbjct: 425 LFDRL-TVEEHLWFYSR-LKSMAQEEIRREMDKMIEDLELSNKRHSLVQTLSGGMKRKLS 482
Query: 400 LVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMATYLADR 221
+ + + ++DEP+A +D R +I ++ RT + H A L DR
Sbjct: 483 VAIAFVGGSRAIILDEPTAGVDPYARRAIWDLILKY--KPGRTILLSTHHMDEADLLGDR 540
Query: 220 VIV 212
+ +
Sbjct: 541 IAI 543
>AB028985-1|BAA83014.2| 1771|Homo sapiens KIAA1062 protein protein.
Length = 1771
Score = 43.2 bits (97), Expect = 0.001
Identities = 48/183 (26%), Positives = 84/183 (45%), Gaps = 18/183 (9%)
Frame = -3
Query: 706 DSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQKISPKSQGLV--RSL 533
+++++ LG NG GKTT + +L G P GS + I + +I K+ G+ ++
Sbjct: 352 ENQVVSFLGHNGAGKTTTMSILTGLFPPTSGSATIYGHDIRTEMDEIR-KNLGMCPQHNV 410
Query: 532 LHDKIRDAYIHPQFLTDVMKPMKIEEI---MDQE-------------VQNLSGGELQRVA 401
L D++ H F + +K M EEI MD+ VQ LSGG ++++
Sbjct: 411 LFDRL-TVEEHLWFYSR-LKSMAQEEIRREMDKMIEDLELSNKRHSLVQTLSGGMKRKLS 468
Query: 400 LVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMATYLADR 221
+ + + ++DEP+A +D R +I ++ RT + H A L DR
Sbjct: 469 VAIAFVGGSRAIILDEPTAGVDPYARRAIWDLILKY--KPGRTILLSTHHMDEADLLGDR 526
Query: 220 VIV 212
+ +
Sbjct: 527 IAI 529
>X96395-1|CAA65259.2| 1545|Homo sapiens canalicular multidrug
resistance protein protein.
Length = 1545
Score = 42.3 bits (95), Expect = 0.002
Identities = 43/190 (22%), Positives = 90/190 (47%), Gaps = 9/190 (4%)
Frame = -3
Query: 742 DFGLRVMPGEFSDSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQKIS 563
D L +M G+ ++ ++G G+GK++ I + G +E G + +Y PQ+
Sbjct: 656 DVNLDIMAGQ-----LVAVIGPVGSGKSSLISAMLGEMENVHGHITIKGT-TAYVPQQSW 709
Query: 562 PKSQGLVRSLLHDKIRDAYIHPQFLT--------DVMKPMKIEEIMDQEVQNLSGGELQR 407
++ + ++L + + Q L +++ + EI ++ + NLSGG+ QR
Sbjct: 710 IQNGTIKDNILFGTEFNEKRYQQVLEACALLPDLEMLPGGDLAEIGEKGI-NLSGGQKQR 768
Query: 406 VALVLCLGKPADVYLIDEPSAYLDSE-QRLVAAKVIKRFILHAKRTGFVVEHDFIMATYL 230
++L + D+YL+D+P + +D+ + + KV+ L +T +V H +
Sbjct: 769 ISLARATYQNLDIYLLDDPLSAVDAHVGKHIFNKVLGPNGLLKGKTRLLVTHSMHFLPQV 828
Query: 229 ADRVIVFEGT 200
+ V++ GT
Sbjct: 829 DEIVVLGNGT 838
>U63970-1|AAB39892.1| 1545|Homo sapiens canalicular multispecific
organic anion transporter protein.
Length = 1545
Score = 42.3 bits (95), Expect = 0.002
Identities = 43/190 (22%), Positives = 90/190 (47%), Gaps = 9/190 (4%)
Frame = -3
Query: 742 DFGLRVMPGEFSDSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQKIS 563
D L +M G+ ++ ++G G+GK++ I + G +E G + +Y PQ+
Sbjct: 656 DVNLDIMAGQ-----LVAVIGPVGSGKSSLISAMLGEMENVHGHITIKGT-TAYVPQQSW 709
Query: 562 PKSQGLVRSLLHDKIRDAYIHPQFLT--------DVMKPMKIEEIMDQEVQNLSGGELQR 407
++ + ++L + + Q L +++ + EI ++ + NLSGG+ QR
Sbjct: 710 IQNGTIKDNILFGTEFNEKRYQQVLEACALLPDLEMLPGGDLAEIGEKGI-NLSGGQKQR 768
Query: 406 VALVLCLGKPADVYLIDEPSAYLDSE-QRLVAAKVIKRFILHAKRTGFVVEHDFIMATYL 230
++L + D+YL+D+P + +D+ + + KV+ L +T +V H +
Sbjct: 769 ISLARATYQNLDIYLLDDPLSAVDAHVGKHIFNKVLGPNGLLKGKTRLLVTHSMHFLPQV 828
Query: 229 ADRVIVFEGT 200
+ V++ GT
Sbjct: 829 DEIVVLGNGT 838
>U49248-1|AAB09422.1| 1545|Homo sapiens canalicular multispecific
organic anion transporter protein.
Length = 1545
Score = 42.3 bits (95), Expect = 0.002
Identities = 43/190 (22%), Positives = 90/190 (47%), Gaps = 9/190 (4%)
Frame = -3
Query: 742 DFGLRVMPGEFSDSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQKIS 563
D L +M G+ ++ ++G G+GK++ I + G +E G + +Y PQ+
Sbjct: 656 DVNLDIMAGQ-----LVAVIGPVGSGKSSLISAMLGEMENVHGHITIKGT-TAYVPQQSW 709
Query: 562 PKSQGLVRSLLHDKIRDAYIHPQFLT--------DVMKPMKIEEIMDQEVQNLSGGELQR 407
++ + ++L + + Q L +++ + EI ++ + NLSGG+ QR
Sbjct: 710 IQNGTIKDNILFGTEFNEKRYQQVLEACALLPDLEMLPGGDLAEIGEKGI-NLSGGQKQR 768
Query: 406 VALVLCLGKPADVYLIDEPSAYLDSE-QRLVAAKVIKRFILHAKRTGFVVEHDFIMATYL 230
++L + D+YL+D+P + +D+ + + KV+ L +T +V H +
Sbjct: 769 ISLARATYQNLDIYLLDDPLSAVDAHVGKHIFNKVLGPNGLLKGKTRLLVTHSMHFLPQV 828
Query: 229 ADRVIVFEGT 200
+ V++ GT
Sbjct: 829 DEIVVLGNGT 838
>AL392107-3|CAI11010.1| 1545|Homo sapiens ATP-binding cassette,
sub-family C (CFTR/MRP), member 2 protein.
Length = 1545
Score = 42.3 bits (95), Expect = 0.002
Identities = 43/190 (22%), Positives = 90/190 (47%), Gaps = 9/190 (4%)
Frame = -3
Query: 742 DFGLRVMPGEFSDSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQKIS 563
D L +M G+ ++ ++G G+GK++ I + G +E G + +Y PQ+
Sbjct: 656 DVNLDIMAGQ-----LVAVIGPVGSGKSSLISAMLGEMENVHGHITIKGT-TAYVPQQSW 709
Query: 562 PKSQGLVRSLLHDKIRDAYIHPQFLT--------DVMKPMKIEEIMDQEVQNLSGGELQR 407
++ + ++L + + Q L +++ + EI ++ + NLSGG+ QR
Sbjct: 710 IQNGTIKDNILFGTEFNEKRYQQVLEACALLPDLEMLPGGDLAEIGEKGI-NLSGGQKQR 768
Query: 406 VALVLCLGKPADVYLIDEPSAYLDSE-QRLVAAKVIKRFILHAKRTGFVVEHDFIMATYL 230
++L + D+YL+D+P + +D+ + + KV+ L +T +V H +
Sbjct: 769 ISLARATYQNLDIYLLDDPLSAVDAHVGKHIFNKVLGPNGLLKGKTRLLVTHSMHFLPQV 828
Query: 229 ADRVIVFEGT 200
+ V++ GT
Sbjct: 829 DEIVVLGNGT 838
>AL133353-7|CAI14502.1| 1545|Homo sapiens ATP-binding cassette,
sub-family C (CFTR/MRP), member 2 protein.
Length = 1545
Score = 42.3 bits (95), Expect = 0.002
Identities = 43/190 (22%), Positives = 90/190 (47%), Gaps = 9/190 (4%)
Frame = -3
Query: 742 DFGLRVMPGEFSDSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQKIS 563
D L +M G+ ++ ++G G+GK++ I + G +E G + +Y PQ+
Sbjct: 656 DVNLDIMAGQ-----LVAVIGPVGSGKSSLISAMLGEMENVHGHITIKGT-TAYVPQQSW 709
Query: 562 PKSQGLVRSLLHDKIRDAYIHPQFLT--------DVMKPMKIEEIMDQEVQNLSGGELQR 407
++ + ++L + + Q L +++ + EI ++ + NLSGG+ QR
Sbjct: 710 IQNGTIKDNILFGTEFNEKRYQQVLEACALLPDLEMLPGGDLAEIGEKGI-NLSGGQKQR 768
Query: 406 VALVLCLGKPADVYLIDEPSAYLDSE-QRLVAAKVIKRFILHAKRTGFVVEHDFIMATYL 230
++L + D+YL+D+P + +D+ + + KV+ L +T +V H +
Sbjct: 769 ISLARATYQNLDIYLLDDPLSAVDAHVGKHIFNKVLGPNGLLKGKTRLLVTHSMHFLPQV 828
Query: 229 ADRVIVFEGT 200
+ V++ GT
Sbjct: 829 DEIVVLGNGT 838
>AJ132244-1|CAB45309.1| 1545|Homo sapiens multidrug resistance protein
2 (MRP2) protein.
Length = 1545
Score = 42.3 bits (95), Expect = 0.002
Identities = 43/190 (22%), Positives = 90/190 (47%), Gaps = 9/190 (4%)
Frame = -3
Query: 742 DFGLRVMPGEFSDSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQKIS 563
D L +M G+ ++ ++G G+GK++ I + G +E G + +Y PQ+
Sbjct: 656 DVNLDIMAGQ-----LVAVIGPVGSGKSSLISAMLGEMENVHGHITIKGT-TAYVPQQSW 709
Query: 562 PKSQGLVRSLLHDKIRDAYIHPQFLT--------DVMKPMKIEEIMDQEVQNLSGGELQR 407
++ + ++L + + Q L +++ + EI ++ + NLSGG+ QR
Sbjct: 710 IQNGTIKDNILFGTEFNEKRYQQVLEACALLPDLEMLPGGDLAEIGEKGI-NLSGGQKQR 768
Query: 406 VALVLCLGKPADVYLIDEPSAYLDSE-QRLVAAKVIKRFILHAKRTGFVVEHDFIMATYL 230
++L + D+YL+D+P + +D+ + + KV+ L +T +V H +
Sbjct: 769 ISLARATYQNLDIYLLDDPLSAVDAHVGKHIFNKVLGPNGLLKGKTRLLVTHSMHFLPQV 828
Query: 229 ADRVIVFEGT 200
+ V++ GT
Sbjct: 829 DEIVVLGNGT 838
>AF352582-1|AAK19755.1| 1382|Homo sapiens ATP-binding cassette
transporter MRP8 protein.
Length = 1382
Score = 42.3 bits (95), Expect = 0.002
Identities = 45/202 (22%), Positives = 94/202 (46%), Gaps = 8/202 (3%)
Frame = -3
Query: 709 SDSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQKISPKSQGLVRSLL 530
S +L + G G+GK++ + + + EGS + Q ++Y PQ+ S + ++L
Sbjct: 535 SKGMMLGVCGNTGSGKSSLLSAILEEMHLLEGSVGV-QGSLAYVPQQAWIVSGNIRENIL 593
Query: 529 ----HDKIRDAYI-HPQFLTDVMKPMKIEEIMD--QEVQNLSGGELQRVALVLCLGKPAD 371
+DK R + H L ++ + ++ + + NLSGG+ QR++L +
Sbjct: 594 MGGAYDKARYLQVLHCCSLNRDLELLPFGDMTEIGERGPNLSGGQKQRISLARAVYSDRQ 653
Query: 370 VYLIDEPSAYLDSE-QRLVAAKVIKRFILHAKRTGFVVEHDFIMATYLADRVIVFEGTPS 194
+YL+D+P + +D+ + + + IK+ + +T V H + +++ G
Sbjct: 654 IYLLDDPLSAVDAHVGKHIFEECIKKTL--RGKTVVQVTHQLQYLEFCGQVILLENGKIC 711
Query: 193 SNATAHAPQSLLNGMNKFLELL 128
N T H+ L+ K+ +L+
Sbjct: 712 ENGT-HS--ELMQKKGKYAQLI 730
>U83661-1|AAB71758.2| 1437|Homo sapiens multidrug resistance protein
5 protein.
Length = 1437
Score = 41.9 bits (94), Expect = 0.003
Identities = 34/136 (25%), Positives = 64/136 (47%), Gaps = 8/136 (5%)
Frame = -3
Query: 715 EFSDSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQKISPKSQGLVRS 536
E + +++ + G G+GKT+ I + G + EGS + +Y Q+ + L +
Sbjct: 584 EIQEGKLVGICGSVGSGKTSLISAILGQMTLLEGSIAISGT-FAYVAQQAWILNATLRDN 642
Query: 535 LLHDKIRDAYIHPQFLTD--------VMKPMKIEEIMDQEVQNLSGGELQRVALVLCLGK 380
+L K D + L ++ + EI ++ NLSGG+ QR++L L
Sbjct: 643 ILFGKEYDEERYNSVLNSCCLRPDLAILPSSDLTEIGERGA-NLSGGQRQRISLARALYS 701
Query: 379 PADVYLIDEPSAYLDS 332
+Y++D+P + LD+
Sbjct: 702 DRSIYILDDPLSALDA 717
Score = 34.3 bits (75), Expect = 0.51
Identities = 28/99 (28%), Positives = 47/99 (47%), Gaps = 6/99 (6%)
Frame = -3
Query: 472 PMKIEEIMDQEVQNLSGGELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKR- 296
P+K+E + + N S GE Q + + L + + ++DE +A +D+E L+ + I+
Sbjct: 1316 PLKLESEVMENGDNFSVGERQLLCIARALLRHCKILILDEATAAMDTETDLLIQETIREA 1375
Query: 295 -----FILHAKRTGFVVEHDFIMATYLADRVIVFEGTPS 194
+ A R V+ D IM LA +V TPS
Sbjct: 1376 FADCTMLTIAHRLHTVLGSDRIMV--LAQGQVVEFDTPS 1412
>BC151235-1|AAI51236.1| 718|Homo sapiens ATP-binding cassette,
sub-family B (MDR/TAP), member 8 protein.
Length = 718
Score = 41.9 bits (94), Expect = 0.003
Identities = 28/88 (31%), Positives = 45/88 (51%)
Frame = -3
Query: 517 RDAYIHPQFLTDVMKPMKIEEIMDQEVQNLSGGELQRVALVLCLGKPADVYLIDEPSAYL 338
R+A H +F+T P ++ + LSGG+ QR+A+ L K V ++DE ++ L
Sbjct: 569 REANAH-EFITSF--PEGYNTVVGERGTTLSGGQKQRLAIARALIKQPTVLILDEATSAL 625
Query: 337 DSEQRLVAAKVIKRFILHAKRTGFVVEH 254
D+E V + + R A RT V+ H
Sbjct: 626 DAESERVVQEALDR--ASAGRTVLVIAH 651
>BC141814-1|AAI41815.1| 718|Homo sapiens ATP-binding cassette,
sub-family B (MDR/TAP), member 8 protein.
Length = 718
Score = 41.9 bits (94), Expect = 0.003
Identities = 28/88 (31%), Positives = 45/88 (51%)
Frame = -3
Query: 517 RDAYIHPQFLTDVMKPMKIEEIMDQEVQNLSGGELQRVALVLCLGKPADVYLIDEPSAYL 338
R+A H +F+T P ++ + LSGG+ QR+A+ L K V ++DE ++ L
Sbjct: 569 REANAH-EFITSF--PEGYNTVVGERGTTLSGGQKQRLAIARALIKQPTVLILDEATSAL 625
Query: 337 DSEQRLVAAKVIKRFILHAKRTGFVVEH 254
D+E V + + R A RT V+ H
Sbjct: 626 DAESERVVQEALDR--ASAGRTVLVIAH 651
>AY196484-1|AAO49801.1| 1394|Homo sapiens ATP-binding cassette C5
splicing variant A protein.
Length = 1394
Score = 41.9 bits (94), Expect = 0.003
Identities = 34/136 (25%), Positives = 64/136 (47%), Gaps = 8/136 (5%)
Frame = -3
Query: 715 EFSDSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQKISPKSQGLVRS 536
E + +++ + G G+GKT+ I + G + EGS + +Y Q+ + L +
Sbjct: 584 EIQEGKLVGICGSVGSGKTSLISAILGQMTLLEGSIAISGT-FAYVAQQAWILNATLRDN 642
Query: 535 LLHDKIRDAYIHPQFLTD--------VMKPMKIEEIMDQEVQNLSGGELQRVALVLCLGK 380
+L K D + L ++ + EI ++ NLSGG+ QR++L L
Sbjct: 643 ILFGKEYDEERYNSVLNSCCLRPDLAILPSSDLTEIGERGA-NLSGGQRQRISLARALYS 701
Query: 379 PADVYLIDEPSAYLDS 332
+Y++D+P + LD+
Sbjct: 702 DRSIYILDDPLSALDA 717
Score = 34.3 bits (75), Expect = 0.51
Identities = 28/99 (28%), Positives = 47/99 (47%), Gaps = 6/99 (6%)
Frame = -3
Query: 472 PMKIEEIMDQEVQNLSGGELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKR- 296
P+K+E + + N S GE Q + + L + + ++DE +A +D+E L+ + I+
Sbjct: 1273 PLKLESEVMENGDNFSVGERQLLCIARALLRHCKILILDEATAAMDTETDLLIQETIREA 1332
Query: 295 -----FILHAKRTGFVVEHDFIMATYLADRVIVFEGTPS 194
+ A R V+ D IM LA +V TPS
Sbjct: 1333 FADCTMLTIAHRLHTVLGSDRIMV--LAQGQVVEFDTPS 1369
>AK222911-1|BAD96631.1| 718|Homo sapiens ATP-binding cassette,
sub-family B, member 8 variant protein.
Length = 718
Score = 41.9 bits (94), Expect = 0.003
Identities = 28/88 (31%), Positives = 45/88 (51%)
Frame = -3
Query: 517 RDAYIHPQFLTDVMKPMKIEEIMDQEVQNLSGGELQRVALVLCLGKPADVYLIDEPSAYL 338
R+A H +F+T P ++ + LSGG+ QR+A+ L K V ++DE ++ L
Sbjct: 569 REANAH-EFITSF--PEGYNTVVGERGTTLSGGQKQRLAIARALIKQPTVLILDEATSAL 625
Query: 337 DSEQRLVAAKVIKRFILHAKRTGFVVEH 254
D+E V + + R A RT V+ H
Sbjct: 626 DAESERVVQEALDR--ASAGRTVLVIAH 651
>AK094636-1|BAC04392.1| 701|Homo sapiens protein ( Homo sapiens
cDNA FLJ37317 fis, clone BRAMY2017455, highly similar to
Homo sapiens ATP-binding cassette protein M-ABC1 mRNA.
).
Length = 701
Score = 41.9 bits (94), Expect = 0.003
Identities = 28/88 (31%), Positives = 45/88 (51%)
Frame = -3
Query: 517 RDAYIHPQFLTDVMKPMKIEEIMDQEVQNLSGGELQRVALVLCLGKPADVYLIDEPSAYL 338
R+A H +F+T P ++ + LSGG+ QR+A+ L K V ++DE ++ L
Sbjct: 552 REANAH-EFITSF--PEGYNTVVGERGTTLSGGQKQRLAIARALIKQPTVLILDEATSAL 608
Query: 337 DSEQRLVAAKVIKRFILHAKRTGFVVEH 254
D+E V + + R A RT V+ H
Sbjct: 609 DAESERVVQEALDR--ASAGRTVLVIAH 634
>AK002018-1|BAA92038.1| 735|Homo sapiens protein ( Homo sapiens
cDNA FLJ11156 fis, clone PLACE1006956, weakly similar to
ATP-DEPENDENT PERMEASE MDL1. ).
Length = 735
Score = 41.9 bits (94), Expect = 0.003
Identities = 28/88 (31%), Positives = 45/88 (51%)
Frame = -3
Query: 517 RDAYIHPQFLTDVMKPMKIEEIMDQEVQNLSGGELQRVALVLCLGKPADVYLIDEPSAYL 338
R+A H +F+T P ++ + LSGG+ QR+A+ L K V ++DE ++ L
Sbjct: 586 REANAH-EFITSF--PEGYNTVVGERGTTLSGGQKQRLAIARALIKQPTVLILDEATSAL 642
Query: 337 DSEQRLVAAKVIKRFILHAKRTGFVVEH 254
D+E V + + R A RT V+ H
Sbjct: 643 DAESERVVQEALDR--ASAGRTVLVIAH 668
>AF146074-1|AAD37716.1| 1437|Homo sapiens ABC protein protein.
Length = 1437
Score = 41.9 bits (94), Expect = 0.003
Identities = 34/136 (25%), Positives = 64/136 (47%), Gaps = 8/136 (5%)
Frame = -3
Query: 715 EFSDSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQKISPKSQGLVRS 536
E + +++ + G G+GKT+ I + G + EGS + +Y Q+ + L +
Sbjct: 584 EIQEGKLVGICGSVGSGKTSLISAILGQMTLLEGSIAISGT-FAYVAQQAWILNATLRDN 642
Query: 535 LLHDKIRDAYIHPQFLTD--------VMKPMKIEEIMDQEVQNLSGGELQRVALVLCLGK 380
+L K D + L ++ + EI ++ NLSGG+ QR++L L
Sbjct: 643 ILFGKEYDEERYNSVLNSCCLRPDLAILPSSDLTEIGERGA-NLSGGQRQRISLARALYS 701
Query: 379 PADVYLIDEPSAYLDS 332
+Y++D+P + LD+
Sbjct: 702 DRSIYILDDPLSALDA 717
Score = 34.3 bits (75), Expect = 0.51
Identities = 28/99 (28%), Positives = 47/99 (47%), Gaps = 6/99 (6%)
Frame = -3
Query: 472 PMKIEEIMDQEVQNLSGGELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKR- 296
P+K+E + + N S GE Q + + L + + ++DE +A +D+E L+ + I+
Sbjct: 1316 PLKLESEVMENGDNFSVGERQLLCIARALLRHCKILILDEATAAMDTETDLLIQETIREA 1375
Query: 295 -----FILHAKRTGFVVEHDFIMATYLADRVIVFEGTPS 194
+ A R V+ D IM LA +V TPS
Sbjct: 1376 FADCTMLTIAHRLHTVLGSDRIMV--LAQGQVVEFDTPS 1412
>AF104942-1|AAD04169.1| 1437|Homo sapiens ABC transporter MOAT-C
protein.
Length = 1437
Score = 41.9 bits (94), Expect = 0.003
Identities = 34/136 (25%), Positives = 64/136 (47%), Gaps = 8/136 (5%)
Frame = -3
Query: 715 EFSDSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQKISPKSQGLVRS 536
E + +++ + G G+GKT+ I + G + EGS + +Y Q+ + L +
Sbjct: 584 EIQEGKLVGICGSVGSGKTSLISAILGQMTLLEGSIAISGT-FAYVAQQAWILNATLRDN 642
Query: 535 LLHDKIRDAYIHPQFLTD--------VMKPMKIEEIMDQEVQNLSGGELQRVALVLCLGK 380
+L K D + L ++ + EI ++ NLSGG+ QR++L L
Sbjct: 643 ILFGKEYDEERYNSVLNSCCLRPDLAILPSSDLTEIGERGA-NLSGGQRQRISLARALYS 701
Query: 379 PADVYLIDEPSAYLDS 332
+Y++D+P + LD+
Sbjct: 702 DRSIYILDDPLSALDA 717
Score = 34.3 bits (75), Expect = 0.51
Identities = 28/99 (28%), Positives = 47/99 (47%), Gaps = 6/99 (6%)
Frame = -3
Query: 472 PMKIEEIMDQEVQNLSGGELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKR- 296
P+K+E + + N S GE Q + + L + + ++DE +A +D+E L+ + I+
Sbjct: 1316 PLKLESEVMENGDNFSVGERQLLCIARALLRHCKILILDEATAAMDTETDLLIQETIREA 1375
Query: 295 -----FILHAKRTGFVVEHDFIMATYLADRVIVFEGTPS 194
+ A R V+ D IM LA +V TPS
Sbjct: 1376 FADCTMLTIAHRLHTVLGSDRIMV--LAQGQVVEFDTPS 1412
>AF047690-1|AAD15748.1| 718|Homo sapiens ATP-binding cassette
protein M-ABC1 protein.
Length = 718
Score = 41.9 bits (94), Expect = 0.003
Identities = 28/88 (31%), Positives = 45/88 (51%)
Frame = -3
Query: 517 RDAYIHPQFLTDVMKPMKIEEIMDQEVQNLSGGELQRVALVLCLGKPADVYLIDEPSAYL 338
R+A H +F+T P ++ + LSGG+ QR+A+ L K V ++DE ++ L
Sbjct: 569 REANAH-EFITSF--PEGYNTVVGERGTTLSGGQKQRLAIARALIKQPTVLILDEATSAL 625
Query: 337 DSEQRLVAAKVIKRFILHAKRTGFVVEH 254
D+E V + + R A RT V+ H
Sbjct: 626 DAESERVVQEALDR--ASAGRTVLVIAH 651
>AB209454-1|BAD92691.1| 1430|Homo sapiens Multidrug
resistance-associated protein 5 variant protein.
Length = 1430
Score = 41.9 bits (94), Expect = 0.003
Identities = 34/136 (25%), Positives = 64/136 (47%), Gaps = 8/136 (5%)
Frame = -3
Query: 715 EFSDSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQKISPKSQGLVRS 536
E + +++ + G G+GKT+ I + G + EGS + +Y Q+ + L +
Sbjct: 577 EIQEGKLVGICGSVGSGKTSLISAILGQMTLLEGSIAISGT-FAYVAQQAWILNATLRDN 635
Query: 535 LLHDKIRDAYIHPQFLTD--------VMKPMKIEEIMDQEVQNLSGGELQRVALVLCLGK 380
+L K D + L ++ + EI ++ NLSGG+ QR++L L
Sbjct: 636 ILFGKEYDEERYNSVLNSCCLRPDLAILPSSDLTEIGERGA-NLSGGQRQRISLARALYS 694
Query: 379 PADVYLIDEPSAYLDS 332
+Y++D+P + LD+
Sbjct: 695 DRSIYILDDPLSALDA 710
Score = 34.3 bits (75), Expect = 0.51
Identities = 28/99 (28%), Positives = 47/99 (47%), Gaps = 6/99 (6%)
Frame = -3
Query: 472 PMKIEEIMDQEVQNLSGGELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKR- 296
P+K+E + + N S GE Q + + L + + ++DE +A +D+E L+ + I+
Sbjct: 1309 PLKLESEVMENGDNFSVGERQLLCIARALLRHCKILILDEATAAMDTETDLLIQETIREA 1368
Query: 295 -----FILHAKRTGFVVEHDFIMATYLADRVIVFEGTPS 194
+ A R V+ D IM LA +V TPS
Sbjct: 1369 FADCTMLTIAHRLHTVLGSDRIMV--LAQGQVVEFDTPS 1405
>AB209103-1|BAD92340.1| 799|Homo sapiens ATP-binding cassette C5
splicing variant A variant protein.
Length = 799
Score = 41.9 bits (94), Expect = 0.003
Identities = 34/136 (25%), Positives = 64/136 (47%), Gaps = 8/136 (5%)
Frame = -3
Query: 715 EFSDSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQKISPKSQGLVRS 536
E + +++ + G G+GKT+ I + G + EGS + +Y Q+ + L +
Sbjct: 482 EIQEGKLVGICGSVGSGKTSLISAILGQMTLLEGSIAISGT-FAYVAQQAWILNATLRDN 540
Query: 535 LLHDKIRDAYIHPQFLTD--------VMKPMKIEEIMDQEVQNLSGGELQRVALVLCLGK 380
+L K D + L ++ + EI ++ NLSGG+ QR++L L
Sbjct: 541 ILFGKEYDEERYNSVLNSCCLRPDLAILPSSDLTEIGERGA-NLSGGQRQRISLARALYS 599
Query: 379 PADVYLIDEPSAYLDS 332
+Y++D+P + LD+
Sbjct: 600 DRSIYILDDPLSALDA 615
>AB019002-1|BAA76608.1| 1437|Homo sapiens MRP5 protein.
Length = 1437
Score = 41.9 bits (94), Expect = 0.003
Identities = 34/136 (25%), Positives = 64/136 (47%), Gaps = 8/136 (5%)
Frame = -3
Query: 715 EFSDSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQKISPKSQGLVRS 536
E + +++ + G G+GKT+ I + G + EGS + +Y Q+ + L +
Sbjct: 584 EIQEGKLVGICGSVGSGKTSLISAILGQMTLLEGSIAISGT-FAYVAQQAWILNATLRDN 642
Query: 535 LLHDKIRDAYIHPQFLTD--------VMKPMKIEEIMDQEVQNLSGGELQRVALVLCLGK 380
+L K D + L ++ + EI ++ NLSGG+ QR++L L
Sbjct: 643 ILFGKEYDEERYNSVLNSCCLRPDLAILPSSDLTEIGERGA-NLSGGQRQRISLARALYS 701
Query: 379 PADVYLIDEPSAYLDS 332
+Y++D+P + LD+
Sbjct: 702 DRSIYILDDPLSALDA 717
Score = 33.9 bits (74), Expect = 0.67
Identities = 16/58 (27%), Positives = 32/58 (55%)
Frame = -3
Query: 472 PMKIEEIMDQEVQNLSGGELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIK 299
P+K+E + + N S GE Q + + L + + ++DE +A +D+E L+ + I+
Sbjct: 1316 PLKLESEVMENGDNFSVGERQLLCIARALLRHCKILILDEATAAMDTETDLLIQETIR 1373
>AB005659-1|BAA22887.1| 946|Homo sapiens SMRP protein.
Length = 946
Score = 41.9 bits (94), Expect = 0.003
Identities = 34/136 (25%), Positives = 64/136 (47%), Gaps = 8/136 (5%)
Frame = -3
Query: 715 EFSDSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQKISPKSQGLVRS 536
E + +++ + G G+GKT+ I + G + EGS + +Y Q+ + L +
Sbjct: 93 EIQEGKLVGICGSVGSGKTSLISAILGQMTLLEGSIAISGT-FAYVAQQAWILNATLRDN 151
Query: 535 LLHDKIRDAYIHPQFLTD--------VMKPMKIEEIMDQEVQNLSGGELQRVALVLCLGK 380
+L K D + L ++ + EI ++ NLSGG+ QR++L L
Sbjct: 152 ILFGKEYDEERYNSVLNSCCLRPDLAILPSSDLTEIGERGA-NLSGGQRQRISLARALYS 210
Query: 379 PADVYLIDEPSAYLDS 332
+Y++D+P + LD+
Sbjct: 211 DRSIYILDDPLSALDA 226
Score = 33.9 bits (74), Expect = 0.67
Identities = 16/58 (27%), Positives = 32/58 (55%)
Frame = -3
Query: 472 PMKIEEIMDQEVQNLSGGELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIK 299
P+K+E + + N S GE Q + + L + + ++DE +A +D+E L+ + I+
Sbjct: 825 PLKLESEVMENGDNFSVGERQLLCIARALLRHCKILILDEATAAMDTETDLLIQETIR 882
>BC104920-1|AAI04921.1| 812|Homo sapiens ATP-binding cassette,
sub-family B (MDR/TAP), member 5 protein.
Length = 812
Score = 41.5 bits (93), Expect = 0.003
Identities = 26/108 (24%), Positives = 50/108 (46%)
Frame = -3
Query: 472 PMKIEEIMDQEVQNLSGGELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRF 293
P K ++ ++ +SGG+ QR+A+ L + + ++DE ++ LDSE + +++
Sbjct: 66 PNKFNTLVGEKGAQMSGGQKQRIAIARALVRNPKILILDEATSALDSESKSAVQAALEK- 124
Query: 292 ILHAKRTGFVVEHDFIMATYLADRVIVFEGTPSSNATAHAPQSLLNGM 149
RT VV H + AD ++ + + AHA G+
Sbjct: 125 -ASKGRTTIVVAHR-LSTIRSADLIVTLKDGMLAEKGAHAELMAKRGL 170
Score = 37.9 bits (84), Expect = 0.041
Identities = 28/101 (27%), Positives = 47/101 (46%)
Frame = -3
Query: 430 LSGGELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHD 251
LSGG+ QR+A+ L + + L+DE ++ LD++ V + + RT VV H
Sbjct: 711 LSGGQKQRLAIARALLQKPKILLLDEATSALDNDSEKVVQHALDK--ARTGRTCLVVTHR 768
Query: 250 FIMATYLADRVIVFEGTPSSNATAHAPQSLLNGMNKFLELL 128
+ A AD ++V H Q LL + + +L+
Sbjct: 769 -LSAIQNADLIVVLHNGKIKEQGTH--QELLRNRDIYFKLV 806
>BC104894-1|AAI04895.2| 812|Homo sapiens ATP-binding cassette,
sub-family B (MDR/TAP), member 5 protein.
Length = 812
Score = 41.5 bits (93), Expect = 0.003
Identities = 26/108 (24%), Positives = 50/108 (46%)
Frame = -3
Query: 472 PMKIEEIMDQEVQNLSGGELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRF 293
P K ++ ++ +SGG+ QR+A+ L + + ++DE ++ LDSE + +++
Sbjct: 66 PNKFNTLVGEKGAQMSGGQKQRIAIARALVRNPKILILDEATSALDSESKSAVQAALEK- 124
Query: 292 ILHAKRTGFVVEHDFIMATYLADRVIVFEGTPSSNATAHAPQSLLNGM 149
RT VV H + AD ++ + + AHA G+
Sbjct: 125 -ASKGRTTIVVAHR-LSTIRSADLIVTLKDGMLAEKGAHAELMAKRGL 170
Score = 37.9 bits (84), Expect = 0.041
Identities = 28/101 (27%), Positives = 47/101 (46%)
Frame = -3
Query: 430 LSGGELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHD 251
LSGG+ QR+A+ L + + L+DE ++ LD++ V + + RT VV H
Sbjct: 711 LSGGQKQRLAIARALLQKPKILLLDEATSALDNDSEKVVQHALDK--ARTGRTCLVVTHR 768
Query: 250 FIMATYLADRVIVFEGTPSSNATAHAPQSLLNGMNKFLELL 128
+ A AD ++V H Q LL + + +L+
Sbjct: 769 -LSAIQNADLIVVLHNGKIKEQGTH--QELLRNRDIYFKLV 806
>AY234788-1|AAO73470.1| 812|Homo sapiens P-glycoprotein ABCB5
protein.
Length = 812
Score = 41.5 bits (93), Expect = 0.003
Identities = 26/108 (24%), Positives = 50/108 (46%)
Frame = -3
Query: 472 PMKIEEIMDQEVQNLSGGELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRF 293
P K ++ ++ +SGG+ QR+A+ L + + ++DE ++ LDSE + +++
Sbjct: 66 PNKFNTLVGEKGAQMSGGQKQRIAIARALVRNPKILILDEATSALDSESKSAVQAALEK- 124
Query: 292 ILHAKRTGFVVEHDFIMATYLADRVIVFEGTPSSNATAHAPQSLLNGM 149
RT VV H + AD ++ + + AHA G+
Sbjct: 125 -ASKGRTTIVVAHR-LSTIRSADLIVTLKDGMLAEKGAHAELMAKRGL 170
Score = 37.9 bits (84), Expect = 0.041
Identities = 28/101 (27%), Positives = 47/101 (46%)
Frame = -3
Query: 430 LSGGELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHD 251
LSGG+ QR+A+ L + + L+DE ++ LD++ V + + RT VV H
Sbjct: 711 LSGGQKQRLAIARALLQKPKILLLDEATSALDNDSEKVVQHALDK--ARTGRTCLVVTHR 768
Query: 250 FIMATYLADRVIVFEGTPSSNATAHAPQSLLNGMNKFLELL 128
+ A AD ++V H Q LL + + +L+
Sbjct: 769 -LSAIQNADLIVVLHNGKIKEQGTH--QELLRNRDIYFKLV 806
>AY219711-1|AAP21093.1| 2595|Homo sapiens ABCA12 transporter subfamily
A protein.
Length = 2595
Score = 41.5 bits (93), Expect = 0.003
Identities = 40/150 (26%), Positives = 70/150 (46%), Gaps = 17/150 (11%)
Frame = -3
Query: 700 EILVLLGENGTGKTTFIRMLAGNLEPDEGS-------GQLPQLH-----ISYKPQKISPK 557
E LLG NG GKTT +ML G++ P G+ G L + + Y PQ+ +
Sbjct: 2284 ECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKTGSLGHVDSHSSLVGYCPQEDALD 2343
Query: 556 SQGLVRSLLHDKIRDAYIHPQFLTD----VMKPMKIEEIMDQEVQNLSGGELQRVALVLC 389
V L+ R I + + + +++ + + D+ S G ++++ L
Sbjct: 2344 DLVTVEEHLYFYARVHGIPEKDIKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALA 2403
Query: 388 L-GKPADVYLIDEPSAYLDSEQRLVAAKVI 302
L GKP+ + L+DEPS+ +D + + K+I
Sbjct: 2404 LIGKPS-ILLLDEPSSGMDPKSKRHLWKII 2432
Score = 39.1 bits (87), Expect = 0.018
Identities = 50/186 (26%), Positives = 77/186 (41%), Gaps = 17/186 (9%)
Frame = -3
Query: 712 FSDSEILVLLGENGTGKTTFIRMLAGNLEPDEGS----GQ--LPQLHISYKPQKISPKSQ 551
F + I LLG NG GKTT I ML G G+ G+ LH K + +
Sbjct: 1368 FYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKTDLHTVRKNMGVCMQHD 1427
Query: 550 GLV-------RSLLHDKIR-DAYIHPQFLTDVMKPMK---IEEIMDQEVQNLSGGELQRV 404
L LL+ I+ + Q +V + +K + + V LSGG +++
Sbjct: 1428 VLFSYLTTKEHLLLYGSIKVPHWTKKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKL 1487
Query: 403 ALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMATYLAD 224
++ + L + V ++DEPS +D R VI + RT + H A L+D
Sbjct: 1488 SISIALIGGSRVVILDEPSTGVDPCSRRSIWDVISK--NKTARTIILSTHHLDEAEVLSD 1545
Query: 223 RVIVFE 206
R+ E
Sbjct: 1546 RIAFLE 1551
>AY090613-1|AAM09027.1| 812|Homo sapiens P-glycoprotein protein.
Length = 812
Score = 41.5 bits (93), Expect = 0.003
Identities = 26/108 (24%), Positives = 50/108 (46%)
Frame = -3
Query: 472 PMKIEEIMDQEVQNLSGGELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRF 293
P K ++ ++ +SGG+ QR+A+ L + + ++DE ++ LDSE + +++
Sbjct: 66 PNKFNTLVGEKGAQMSGGQKQRIAIARALVRNPKILILDEATSALDSESKSAVQAALEK- 124
Query: 292 ILHAKRTGFVVEHDFIMATYLADRVIVFEGTPSSNATAHAPQSLLNGM 149
RT VV H + AD ++ + + AHA G+
Sbjct: 125 -ASKGRTTIVVAHR-LSTIRSADLIVTLKDGMLAEKGAHAELMAKRGL 170
Score = 37.9 bits (84), Expect = 0.041
Identities = 28/101 (27%), Positives = 47/101 (46%)
Frame = -3
Query: 430 LSGGELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHD 251
LSGG+ QR+A+ L + + L+DE ++ LD++ V + + RT VV H
Sbjct: 711 LSGGQKQRLAIARALLQKPKILLLDEATSALDNDSEKVVQHALDK--ARTGRTCLVVTHR 768
Query: 250 FIMATYLADRVIVFEGTPSSNATAHAPQSLLNGMNKFLELL 128
+ A AD ++V H Q LL + + +L+
Sbjct: 769 -LSAIQNADLIVVLHNGKIKEQGTH--QELLRNRDIYFKLV 806
>AY033486-1|AAK54355.1| 2277|Homo sapiens ATP-binding cassette
transporter family A member 12 protein.
Length = 2277
Score = 41.5 bits (93), Expect = 0.003
Identities = 40/150 (26%), Positives = 70/150 (46%), Gaps = 17/150 (11%)
Frame = -3
Query: 700 EILVLLGENGTGKTTFIRMLAGNLEPDEGS-------GQLPQLH-----ISYKPQKISPK 557
E LLG NG GKTT +ML G++ P G+ G L + + Y PQ+ +
Sbjct: 1966 ECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKTGSLGHVDSHSSLVGYCPQEDALD 2025
Query: 556 SQGLVRSLLHDKIRDAYIHPQFLTD----VMKPMKIEEIMDQEVQNLSGGELQRVALVLC 389
V L+ R I + + + +++ + + D+ S G ++++ L
Sbjct: 2026 DLVTVEEHLYFYARVHGIPEKDIKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALA 2085
Query: 388 L-GKPADVYLIDEPSAYLDSEQRLVAAKVI 302
L GKP+ + L+DEPS+ +D + + K+I
Sbjct: 2086 LIGKPS-ILLLDEPSSGMDPKSKRHLWKII 2114
Score = 39.1 bits (87), Expect = 0.018
Identities = 50/186 (26%), Positives = 77/186 (41%), Gaps = 17/186 (9%)
Frame = -3
Query: 712 FSDSEILVLLGENGTGKTTFIRMLAGNLEPDEGS----GQ--LPQLHISYKPQKISPKSQ 551
F + I LLG NG GKTT I ML G G+ G+ LH K + +
Sbjct: 1050 FYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKTDLHTVRKNMGVCMQHD 1109
Query: 550 GLV-------RSLLHDKIR-DAYIHPQFLTDVMKPMK---IEEIMDQEVQNLSGGELQRV 404
L LL+ I+ + Q +V + +K + + V LSGG +++
Sbjct: 1110 VLFSYLTTKEHLLLYGSIKVPHWTKKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKL 1169
Query: 403 ALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMATYLAD 224
++ + L + V ++DEPS +D R VI + RT + H A L+D
Sbjct: 1170 SISIALIGGSRVVILDEPSTGVDPCSRRSIWDVISK--NKTARTIILSTHHLDEAEVLSD 1227
Query: 223 RVIVFE 206
R+ E
Sbjct: 1228 RIAFLE 1233
>AF418105-1|AAN40735.1| 2347|Homo sapiens ATP-binding cassette
transporter family A member 12 protein.
Length = 2347
Score = 41.5 bits (93), Expect = 0.003
Identities = 40/150 (26%), Positives = 70/150 (46%), Gaps = 17/150 (11%)
Frame = -3
Query: 700 EILVLLGENGTGKTTFIRMLAGNLEPDEGS-------GQLPQLH-----ISYKPQKISPK 557
E LLG NG GKTT +ML G++ P G+ G L + + Y PQ+ +
Sbjct: 2036 ECFGLLGVNGAGKTTIFKMLTGDIIPSSGNILIRNKTGSLGHVDSHSSLVGYCPQEDALD 2095
Query: 556 SQGLVRSLLHDKIRDAYIHPQFLTD----VMKPMKIEEIMDQEVQNLSGGELQRVALVLC 389
V L+ R I + + + +++ + + D+ S G ++++ L
Sbjct: 2096 DLVTVEEHLYFYARVHGIPEKDIKETVHKLLRRLHLMPFKDRATSMCSYGTKRKLSTALA 2155
Query: 388 L-GKPADVYLIDEPSAYLDSEQRLVAAKVI 302
L GKP+ + L+DEPS+ +D + + K+I
Sbjct: 2156 LIGKPS-ILLLDEPSSGMDPKSKRHLWKII 2184
Score = 39.1 bits (87), Expect = 0.018
Identities = 50/186 (26%), Positives = 77/186 (41%), Gaps = 17/186 (9%)
Frame = -3
Query: 712 FSDSEILVLLGENGTGKTTFIRMLAGNLEPDEGS----GQ--LPQLHISYKPQKISPKSQ 551
F + I LLG NG GKTT I ML G G+ G+ LH K + +
Sbjct: 1120 FYEGHITSLLGPNGAGKTTTISMLTGLFGASAGTIFVYGKDIKTDLHTVRKNMGVCMQHD 1179
Query: 550 GLV-------RSLLHDKIR-DAYIHPQFLTDVMKPMK---IEEIMDQEVQNLSGGELQRV 404
L LL+ I+ + Q +V + +K + + V LSGG +++
Sbjct: 1180 VLFSYLTTKEHLLLYGSIKVPHWTKKQLHEEVKRTLKDTGLYSHRHKRVGTLSGGMKRKL 1239
Query: 403 ALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMATYLAD 224
++ + L + V ++DEPS +D R VI + RT + H A L+D
Sbjct: 1240 SISIALIGGSRVVILDEPSTGVDPCSRRSIWDVISK--NKTARTIILSTHHLDEAEVLSD 1297
Query: 223 RVIVFE 206
R+ E
Sbjct: 1298 RIAFLE 1303
>AF399931-1|AAQ03033.1| 832|Homo sapiens P-glycoprotein protein.
Length = 832
Score = 41.5 bits (93), Expect = 0.003
Identities = 26/108 (24%), Positives = 50/108 (46%)
Frame = -3
Query: 472 PMKIEEIMDQEVQNLSGGELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRF 293
P K ++ ++ +SGG+ QR+A+ L + + ++DE ++ LDSE + +++
Sbjct: 86 PNKFNTLVGEKGAQMSGGQKQRIAIARALVRNPKILILDEATSALDSESKSAVQAALEK- 144
Query: 292 ILHAKRTGFVVEHDFIMATYLADRVIVFEGTPSSNATAHAPQSLLNGM 149
RT VV H + AD ++ + + AHA G+
Sbjct: 145 -ASKGRTTIVVAHR-LSTIRSADLIVTLKDGMLAEKGAHAELMAKRGL 190
Score = 37.9 bits (84), Expect = 0.041
Identities = 28/101 (27%), Positives = 47/101 (46%)
Frame = -3
Query: 430 LSGGELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHD 251
LSGG+ QR+A+ L + + L+DE ++ LD++ V + + RT VV H
Sbjct: 731 LSGGQKQRLAIARALLQKPKILLLDEATSALDNDSEKVVQHALDK--ARTGRTCLVVTHR 788
Query: 250 FIMATYLADRVIVFEGTPSSNATAHAPQSLLNGMNKFLELL 128
+ A AD ++V H Q LL + + +L+
Sbjct: 789 -LSAIQNADLIVVLHNGKIKEQGTH--QELLRNRDIYFKLV 826
>BT007451-1|AAP36119.1| 623|Homo sapiens ATP-binding cassette,
sub-family F (GCN20), member 2 protein.
Length = 623
Score = 40.7 bits (91), Expect = 0.006
Identities = 44/173 (25%), Positives = 76/173 (43%), Gaps = 10/173 (5%)
Frame = -3
Query: 694 LVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQKISPKSQGLVRSLLHDKIR 515
+ L+G NG GK+T +++L G L P +G + H+ KI Q L L D
Sbjct: 426 VALVGPNGAGKSTLLKLLTGELLPTDGMIR-KHSHV-----KIGRYHQHLQEQLDLDLSP 479
Query: 514 DAYIHPQFLTDVMKPMKIEEIMDQ----------EVQNLSGGELQRVALVLCLGKPADVY 365
Y+ + ++ + ++ +I+ + ++NLS G+ RV L + +
Sbjct: 480 LEYMMKCY-PEIKEKEEMRKIIGRYGLTGKQQVSPIRNLSDGQKCRVCLAWLAWQNPHML 538
Query: 364 LIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMATYLADRVIVFE 206
+DEP+ +LD E A I F + +V HDF + +A + V E
Sbjct: 539 FLDEPTNHLDIETIDALADAINEF----EGGMMLVSHDFRLIQQVAQEIWVCE 587
>BC001661-1|AAH01661.1| 623|Homo sapiens ATP-binding cassette,
sub-family F (GCN20), member 2 protein.
Length = 623
Score = 40.7 bits (91), Expect = 0.006
Identities = 44/173 (25%), Positives = 76/173 (43%), Gaps = 10/173 (5%)
Frame = -3
Query: 694 LVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQKISPKSQGLVRSLLHDKIR 515
+ L+G NG GK+T +++L G L P +G + H+ KI Q L L D
Sbjct: 426 VALVGPNGAGKSTLLKLLTGELLPTDGMIR-KHSHV-----KIGRYHQHLQEQLDLDLSP 479
Query: 514 DAYIHPQFLTDVMKPMKIEEIMDQ----------EVQNLSGGELQRVALVLCLGKPADVY 365
Y+ + ++ + ++ +I+ + ++NLS G+ RV L + +
Sbjct: 480 LEYMMKCY-PEIKEKEEMRKIIGRYGLTGKQQVSPIRNLSDGQKCRVCLAWLAWQNPHML 538
Query: 364 LIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMATYLADRVIVFE 206
+DEP+ +LD E A I F + +V HDF + +A + V E
Sbjct: 539 FLDEPTNHLDIETIDALADAINEF----EGGMMLVSHDFRLIQQVAQEIWVCE 587
>AY851365-1|AAW31630.1| 812|Homo sapiens ABCB5beta protein.
Length = 812
Score = 40.7 bits (91), Expect = 0.006
Identities = 26/108 (24%), Positives = 49/108 (45%)
Frame = -3
Query: 472 PMKIEEIMDQEVQNLSGGELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRF 293
P K ++ ++ +SGG+ QR+A+ L + + ++DE ++ LDSE +++
Sbjct: 66 PNKFNTLVGEKGAQMSGGQKQRIAIARALVRNPKILILDEATSALDSESESAVQAALEK- 124
Query: 292 ILHAKRTGFVVEHDFIMATYLADRVIVFEGTPSSNATAHAPQSLLNGM 149
RT VV H + AD ++ + + AHA G+
Sbjct: 125 -ASKGRTTIVVAHR-LSTIRSADLIVTLKDGMLAEKGAHAELMAKRGL 170
Score = 37.9 bits (84), Expect = 0.041
Identities = 28/101 (27%), Positives = 47/101 (46%)
Frame = -3
Query: 430 LSGGELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHD 251
LSGG+ QR+A+ L + + L+DE ++ LD++ V + + RT VV H
Sbjct: 711 LSGGQKQRLAIARALLQKPKILLLDEATSALDNDSEKVVQHALDK--ARTGRTCLVVTHR 768
Query: 250 FIMATYLADRVIVFEGTPSSNATAHAPQSLLNGMNKFLELL 128
+ A AD ++V H Q LL + + +L+
Sbjct: 769 -LSAIQNADLIVVLHNGKIKEQGTH--QELLRNRDIYFKLV 806
>AY204751-1|AAP13576.1| 5058|Homo sapiens ABC A13 protein.
Length = 5058
Score = 40.7 bits (91), Expect = 0.006
Identities = 45/186 (24%), Positives = 83/186 (44%), Gaps = 17/186 (9%)
Frame = -3
Query: 712 FSDSEILVLLGENGTGKTTFIRMLAGNLEPDEG----SGQLPQLHISYKPQK--ISPKSQ 551
F +I LLG NG GKTT I ML G P G +G+ Q +S + + P+
Sbjct: 3865 FYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQTDLSRVRMELGVCPQQD 3924
Query: 550 GLVRSLL---HDKIRDAYIHPQF--------LTDVMKPMKIEEIMDQEVQNLSGGELQRV 404
L+ +L H + + PQ+ + ++ + + + ++ + LSGG +++
Sbjct: 3925 ILLDNLTVREHLLLFASIKAPQWTKKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKL 3984
Query: 403 ALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMATYLAD 224
+L + + ++DEP++ +D R ++ ++ RT H A L+D
Sbjct: 3985 SLGIAFMGMSRTVVLDEPTSGVDPCSRHSLWDILLKY--REGRTIIFTTHHLDEAEALSD 4042
Query: 223 RVIVFE 206
RV V +
Sbjct: 4043 RVAVLQ 4048
Score = 40.3 bits (90), Expect = 0.008
Identities = 41/142 (28%), Positives = 63/142 (44%), Gaps = 20/142 (14%)
Frame = -3
Query: 700 EILVLLGENGTGKTTFIRMLAGNLEPDEGS-------GQLPQLH--------ISYKPQK- 569
E LLG NG GK+T +ML G + G G L I Y PQ+
Sbjct: 4748 ECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIRTPMGDAVDLSSAGTAGVLIGYCPQQD 4807
Query: 568 -ISPKSQGLVRSLLHDKIRDA--YIHPQFLTDVMKPMKIEEIMDQEVQNLSGGELQRVAL 398
+ G + +R P+ D+++ + +E D+ V SGG ++++
Sbjct: 4808 ALDELLTGWEHLYYYCSLRGIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGTKRKLST 4867
Query: 397 VLCL-GKPADVYLIDEPSAYLD 335
L L GKP D+ L+DEPS+ +D
Sbjct: 4868 ALALVGKP-DILLLDEPSSGMD 4888
>AK131360-1|BAD18512.1| 1186|Homo sapiens mRNA. protein.
Length = 1186
Score = 40.7 bits (91), Expect = 0.006
Identities = 45/186 (24%), Positives = 83/186 (44%), Gaps = 17/186 (9%)
Frame = -3
Query: 712 FSDSEILVLLGENGTGKTTFIRMLAGNLEPDEG----SGQLPQLHISYKPQK--ISPKSQ 551
F +I LLG NG GKTT I ML G P G +G+ Q +S + + P+
Sbjct: 125 FYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQTDLSRVRMELGVCPQQD 184
Query: 550 GLVRSLL---HDKIRDAYIHPQF--------LTDVMKPMKIEEIMDQEVQNLSGGELQRV 404
L+ +L H + + PQ+ + ++ + + + ++ + LSGG +++
Sbjct: 185 ILLDNLTVREHLLLFASIKAPQWTKKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKL 244
Query: 403 ALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMATYLAD 224
+L + + ++DEP++ +D R ++ ++ RT H A L+D
Sbjct: 245 SLGIAFMGMSRTVVLDEPTSGVDPCSRHSLWDILLKY--REGRTIIFTTHHLDEAEALSD 302
Query: 223 RVIVFE 206
RV V +
Sbjct: 303 RVAVLQ 308
Score = 40.3 bits (90), Expect = 0.008
Identities = 41/142 (28%), Positives = 63/142 (44%), Gaps = 20/142 (14%)
Frame = -3
Query: 700 EILVLLGENGTGKTTFIRMLAGNLEPDEGS-------GQLPQLH--------ISYKPQK- 569
E LLG NG GK+T +ML G + G G L I Y PQ+
Sbjct: 1008 ECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIRTPMGDAVDLSSAGTAGVLIGYCPQQD 1067
Query: 568 -ISPKSQGLVRSLLHDKIRDA--YIHPQFLTDVMKPMKIEEIMDQEVQNLSGGELQRVAL 398
+ G + +R P+ D+++ + +E D+ V SGG ++++
Sbjct: 1068 ALDELLTGWEHLYYYCSLRGIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGTKRKLST 1127
Query: 397 VLCL-GKPADVYLIDEPSAYLD 335
L L GKP D+ L+DEPS+ +D
Sbjct: 1128 ALALVGKP-DILLLDEPSSGMD 1148
>AJ005016-1|CAA06290.1| 550|Homo sapiens ABC transporter protein.
Length = 550
Score = 40.7 bits (91), Expect = 0.006
Identities = 44/173 (25%), Positives = 76/173 (43%), Gaps = 10/173 (5%)
Frame = -3
Query: 694 LVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQKISPKSQGLVRSLLHDKIR 515
+ L+G NG GK+T +++L G L P +G + H+ KI Q L L D
Sbjct: 353 VALVGPNGAGKSTLLKLLTGELLPTDGMIR-KHSHV-----KIGRYHQHLQEQLDLDLSP 406
Query: 514 DAYIHPQFLTDVMKPMKIEEIMDQ----------EVQNLSGGELQRVALVLCLGKPADVY 365
Y+ + ++ + ++ +I+ + ++NLS G+ RV L + +
Sbjct: 407 LEYMMKCY-PEIKEKEEMRKIIGRYGLTGKQQVSPIRNLSDGQKCRVCLAWLAWQNPHML 465
Query: 364 LIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMATYLADRVIVFE 206
+DEP+ +LD E A I F + +V HDF + +A + V E
Sbjct: 466 FLDEPTNHLDIETIDALADAINEF----EGGMMLVSHDFRLIQQVAQEIWVCE 514
>AF501281-1|AAO59914.1| 2127|Homo sapiens ATP binding cassette
transporter A13 protein.
Length = 2127
Score = 40.7 bits (91), Expect = 0.006
Identities = 45/186 (24%), Positives = 83/186 (44%), Gaps = 17/186 (9%)
Frame = -3
Query: 712 FSDSEILVLLGENGTGKTTFIRMLAGNLEPDEG----SGQLPQLHISYKPQK--ISPKSQ 551
F +I LLG NG GKTT I ML G P G +G+ Q +S + + P+
Sbjct: 933 FYRDQITALLGTNGAGKTTIISMLTGLHPPTSGTIIINGKNLQTDLSRVRMELGVCPQQD 992
Query: 550 GLVRSLL---HDKIRDAYIHPQF--------LTDVMKPMKIEEIMDQEVQNLSGGELQRV 404
L+ +L H + + PQ+ + ++ + + + ++ + LSGG +++
Sbjct: 993 ILLDNLTVREHLLLFASIKAPQWTKKELHQQVNQTLQDVDLTQHQHKQTRALSGGLKRKL 1052
Query: 403 ALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMATYLAD 224
+L + + ++DEP++ +D R ++ ++ RT H A L+D
Sbjct: 1053 SLGIAFMGMSRTVVLDEPTSGVDPCSRHSLWDILLKY--REGRTIIFTTHHLDEAEALSD 1110
Query: 223 RVIVFE 206
RV V +
Sbjct: 1111 RVAVLQ 1116
Score = 40.3 bits (90), Expect = 0.008
Identities = 41/142 (28%), Positives = 63/142 (44%), Gaps = 20/142 (14%)
Frame = -3
Query: 700 EILVLLGENGTGKTTFIRMLAGNLEPDEGS-------GQLPQLH--------ISYKPQK- 569
E LLG NG GK+T +ML G + G G L I Y PQ+
Sbjct: 1817 ECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIRTPMGDAVDLSSAGTAGVLIGYCPQQD 1876
Query: 568 -ISPKSQGLVRSLLHDKIRDA--YIHPQFLTDVMKPMKIEEIMDQEVQNLSGGELQRVAL 398
+ G + +R P+ D+++ + +E D+ V SGG ++++
Sbjct: 1877 ALDELLTGWEHLYYYCSLRGIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGTKRKLST 1936
Query: 397 VLCL-GKPADVYLIDEPSAYLD 335
L L GKP D+ L+DEPS+ +D
Sbjct: 1937 ALALVGKP-DILLLDEPSSGMD 1957
>AF261092-1|AAG13903.1| 623|Homo sapiens iron inhibited ABC
transporter 1 protein.
Length = 623
Score = 40.7 bits (91), Expect = 0.006
Identities = 44/173 (25%), Positives = 76/173 (43%), Gaps = 10/173 (5%)
Frame = -3
Query: 694 LVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQKISPKSQGLVRSLLHDKIR 515
+ L+G NG GK+T +++L G L P +G + H+ KI Q L L D
Sbjct: 426 VALVGPNGAGKSTLLKLLTGELLPTDGMIR-KHSHV-----KIGRYHQHLQEQLDLDLSP 479
Query: 514 DAYIHPQFLTDVMKPMKIEEIMDQ----------EVQNLSGGELQRVALVLCLGKPADVY 365
Y+ + ++ + ++ +I+ + ++NLS G+ RV L + +
Sbjct: 480 LEYMMKCY-PEIKEKEEMRKIIGRYGLTGKQQVSPIRNLSDGQKCRVCLAWLAWQNPHML 538
Query: 364 LIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMATYLADRVIVFE 206
+DEP+ +LD E A I F + +V HDF + +A + V E
Sbjct: 539 FLDEPTNHLDIETIDALADAINEF----EGGMMLVSHDFRLIQQVAQEIWVCE 587
>AF261091-1|AAG13902.1| 623|Homo sapiens iron inhibited ABC
transporter 2 protein.
Length = 623
Score = 40.7 bits (91), Expect = 0.006
Identities = 44/173 (25%), Positives = 76/173 (43%), Gaps = 10/173 (5%)
Frame = -3
Query: 694 LVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQKISPKSQGLVRSLLHDKIR 515
+ L+G NG GK+T +++L G L P +G + H+ KI Q L L D
Sbjct: 426 VALVGPNGAGKSTLLKLLTGELLPTDGMIR-KHSHV-----KIGRYHQHLQEQLDLDLSP 479
Query: 514 DAYIHPQFLTDVMKPMKIEEIMDQ----------EVQNLSGGELQRVALVLCLGKPADVY 365
Y+ + ++ + ++ +I+ + ++NLS G+ RV L + +
Sbjct: 480 LEYMMKCY-PEIKEKEEMRKIIGRYGLTGKQQVSPIRNLSDGQKCRVCLAWLAWQNPHML 538
Query: 364 LIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMATYLADRVIVFE 206
+DEP+ +LD E A I F + +V HDF + +A + V E
Sbjct: 539 FLDEPTNHLDIETIDALADAINEF----EGGMMLVSHDFRLIQQVAQEIWVCE 587
>AC021097-3|AAS00379.1| 623|Homo sapiens unknown protein.
Length = 623
Score = 40.7 bits (91), Expect = 0.006
Identities = 44/173 (25%), Positives = 76/173 (43%), Gaps = 10/173 (5%)
Frame = -3
Query: 694 LVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQKISPKSQGLVRSLLHDKIR 515
+ L+G NG GK+T +++L G L P +G + H+ KI Q L L D
Sbjct: 426 VALVGPNGAGKSTLLKLLTGELLPTDGMIR-KHSHV-----KIGRYHQHLQEQLDLDLSP 479
Query: 514 DAYIHPQFLTDVMKPMKIEEIMDQ----------EVQNLSGGELQRVALVLCLGKPADVY 365
Y+ + ++ + ++ +I+ + ++NLS G+ RV L + +
Sbjct: 480 LEYMMKCY-PEIKEKEEMRKIIGRYGLTGKQQVSPIRNLSDGQKCRVCLAWLAWQNPHML 538
Query: 364 LIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMATYLADRVIVFE 206
+DEP+ +LD E A I F + +V HDF + +A + V E
Sbjct: 539 FLDEPTNHLDIETIDALADAINEF----EGGMMLVSHDFRLIQQVAQEIWVCE 587
>AC021097-2|AAS00378.1| 634|Homo sapiens unknown protein.
Length = 634
Score = 40.7 bits (91), Expect = 0.006
Identities = 44/173 (25%), Positives = 76/173 (43%), Gaps = 10/173 (5%)
Frame = -3
Query: 694 LVLLGENGTGKTTFIRMLAGNLEPDEGSGQLPQLHISYKPQKISPKSQGLVRSLLHDKIR 515
+ L+G NG GK+T +++L G L P +G + H+ KI Q L L D
Sbjct: 426 VALVGPNGAGKSTLLKLLTGELLPTDGMIR-KHSHV-----KIGRYHQHLQEQLDLDLSP 479
Query: 514 DAYIHPQFLTDVMKPMKIEEIMDQ----------EVQNLSGGELQRVALVLCLGKPADVY 365
Y+ + ++ + ++ +I+ + ++NLS G+ RV L + +
Sbjct: 480 LEYMMKCY-PEIKEKEEMRKIIGRYGLTGKQQVSPIRNLSDGQKCRVCLAWLAWQNPHML 538
Query: 364 LIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMATYLADRVIVFE 206
+DEP+ +LD E A I F + +V HDF + +A + V E
Sbjct: 539 FLDEPTNHLDIETIDALADAINEF----EGGMMLVSHDFRLIQQVAQEIWVCE 587
>BX248518-8|CAM26017.1| 845|Homo sapiens ATP-binding cassette
sub-family F (GCN20) member 1 protein.
Length = 845
Score = 40.3 bits (90), Expect = 0.008
Identities = 41/160 (25%), Positives = 70/160 (43%), Gaps = 3/160 (1%)
Frame = -3
Query: 706 DSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLP-QLHISYKPQKISPKSQGLVRSLL 530
DS I ++ G NG GK+T + +L G L P G + +L I + Q+ + + + +
Sbjct: 651 DSRICIV-GPNGVGKSTLLLLLTGKLTPTHGEMRKNHRLKIGFFNQQYAEQLR--MEETP 707
Query: 529 HDKIRDAYIHP-QFLTDVMKPMKIEEIMDQ-EVQNLSGGELQRVALVLCLGKPADVYLID 356
+ ++ + P Q + +E ++ LSGG+ RV + DV ++D
Sbjct: 708 TEYLQRGFNLPYQDARKCLGRFGLESHAHTIQICKLSGGQKARVVFAELACREPDVLILD 767
Query: 355 EPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMAT 236
EP+ LD E + I + K VV HD + T
Sbjct: 768 EPTNNLDIESIDALGEAINEY----KGAVIVVSHDARLIT 803
Score = 33.5 bits (73), Expect = 0.88
Identities = 20/69 (28%), Positives = 35/69 (50%)
Frame = -3
Query: 457 EIMDQEVQNLSGGELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAK 278
E+ ++ Q SGG RV+L L + ++DEP+ +LD L A + ++ +
Sbjct: 443 EMQNRPTQKFSGGWRMRVSLARALFMEPTLLMLDEPTNHLD----LNAVIWLNNYLQGWR 498
Query: 277 RTGFVVEHD 251
+T +V HD
Sbjct: 499 KTLLIVSHD 507
>BX248518-6|CAM26016.1| 807|Homo sapiens ATP-binding cassette
sub-family F (GCN20) member 1 protein.
Length = 807
Score = 40.3 bits (90), Expect = 0.008
Identities = 41/160 (25%), Positives = 70/160 (43%), Gaps = 3/160 (1%)
Frame = -3
Query: 706 DSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLP-QLHISYKPQKISPKSQGLVRSLL 530
DS I ++ G NG GK+T + +L G L P G + +L I + Q+ + + + +
Sbjct: 613 DSRICIV-GPNGVGKSTLLLLLTGKLTPTHGEMRKNHRLKIGFFNQQYAEQLR--MEETP 669
Query: 529 HDKIRDAYIHP-QFLTDVMKPMKIEEIMDQ-EVQNLSGGELQRVALVLCLGKPADVYLID 356
+ ++ + P Q + +E ++ LSGG+ RV + DV ++D
Sbjct: 670 TEYLQRGFNLPYQDARKCLGRFGLESHAHTIQICKLSGGQKARVVFAELACREPDVLILD 729
Query: 355 EPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMAT 236
EP+ LD E + I + K VV HD + T
Sbjct: 730 EPTNNLDIESIDALGEAINEY----KGAVIVVSHDARLIT 765
Score = 33.5 bits (73), Expect = 0.88
Identities = 20/69 (28%), Positives = 35/69 (50%)
Frame = -3
Query: 457 EIMDQEVQNLSGGELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAK 278
E+ ++ Q SGG RV+L L + ++DEP+ +LD L A + ++ +
Sbjct: 405 EMQNRPTQKFSGGWRMRVSLARALFMEPTLLMLDEPTNHLD----LNAVIWLNNYLQGWR 460
Query: 277 RTGFVVEHD 251
+T +V HD
Sbjct: 461 KTLLIVSHD 469
>BX119957-4|CAM25907.1| 845|Homo sapiens ATP-binding cassette
sub-family F (GCN20) member 1 protein.
Length = 845
Score = 40.3 bits (90), Expect = 0.008
Identities = 41/160 (25%), Positives = 70/160 (43%), Gaps = 3/160 (1%)
Frame = -3
Query: 706 DSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLP-QLHISYKPQKISPKSQGLVRSLL 530
DS I ++ G NG GK+T + +L G L P G + +L I + Q+ + + + +
Sbjct: 651 DSRICIV-GPNGVGKSTLLLLLTGKLTPTHGEMRKNHRLKIGFFNQQYAEQLR--MEETP 707
Query: 529 HDKIRDAYIHP-QFLTDVMKPMKIEEIMDQ-EVQNLSGGELQRVALVLCLGKPADVYLID 356
+ ++ + P Q + +E ++ LSGG+ RV + DV ++D
Sbjct: 708 TEYLQRGFNLPYQDARKCLGRFGLESHAHTIQICKLSGGQKARVVFAELACREPDVLILD 767
Query: 355 EPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMAT 236
EP+ LD E + I + K VV HD + T
Sbjct: 768 EPTNNLDIESIDALGEAINEY----KGAVIVVSHDARLIT 803
Score = 33.5 bits (73), Expect = 0.88
Identities = 20/69 (28%), Positives = 35/69 (50%)
Frame = -3
Query: 457 EIMDQEVQNLSGGELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAK 278
E+ ++ Q SGG RV+L L + ++DEP+ +LD L A + ++ +
Sbjct: 443 EMQNRPTQKFSGGWRMRVSLARALFMEPTLLMLDEPTNHLD----LNAVIWLNNYLQGWR 498
Query: 277 RTGFVVEHD 251
+T +V HD
Sbjct: 499 KTLLIVSHD 507
>BX119957-2|CAM25906.1| 807|Homo sapiens ATP-binding cassette
sub-family F (GCN20) member 1 protein.
Length = 807
Score = 40.3 bits (90), Expect = 0.008
Identities = 41/160 (25%), Positives = 70/160 (43%), Gaps = 3/160 (1%)
Frame = -3
Query: 706 DSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLP-QLHISYKPQKISPKSQGLVRSLL 530
DS I ++ G NG GK+T + +L G L P G + +L I + Q+ + + + +
Sbjct: 613 DSRICIV-GPNGVGKSTLLLLLTGKLTPTHGEMRKNHRLKIGFFNQQYAEQLR--MEETP 669
Query: 529 HDKIRDAYIHP-QFLTDVMKPMKIEEIMDQ-EVQNLSGGELQRVALVLCLGKPADVYLID 356
+ ++ + P Q + +E ++ LSGG+ RV + DV ++D
Sbjct: 670 TEYLQRGFNLPYQDARKCLGRFGLESHAHTIQICKLSGGQKARVVFAELACREPDVLILD 729
Query: 355 EPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMAT 236
EP+ LD E + I + K VV HD + T
Sbjct: 730 EPTNNLDIESIDALGEAINEY----KGAVIVVSHDARLIT 765
Score = 33.5 bits (73), Expect = 0.88
Identities = 20/69 (28%), Positives = 35/69 (50%)
Frame = -3
Query: 457 EIMDQEVQNLSGGELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAK 278
E+ ++ Q SGG RV+L L + ++DEP+ +LD L A + ++ +
Sbjct: 405 EMQNRPTQKFSGGWRMRVSLARALFMEPTLLMLDEPTNHLD----LNAVIWLNNYLQGWR 460
Query: 277 RTGFVVEHD 251
+T +V HD
Sbjct: 461 KTLLIVSHD 469
>BX000357-8|CAI18562.1| 807|Homo sapiens ATP-binding cassette,
sub-family F (GCN20), member 1 protein.
Length = 807
Score = 40.3 bits (90), Expect = 0.008
Identities = 41/160 (25%), Positives = 70/160 (43%), Gaps = 3/160 (1%)
Frame = -3
Query: 706 DSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLP-QLHISYKPQKISPKSQGLVRSLL 530
DS I ++ G NG GK+T + +L G L P G + +L I + Q+ + + + +
Sbjct: 613 DSRICIV-GPNGVGKSTLLLLLTGKLTPTHGEMRKNHRLKIGFFNQQYAEQLR--MEETP 669
Query: 529 HDKIRDAYIHP-QFLTDVMKPMKIEEIMDQ-EVQNLSGGELQRVALVLCLGKPADVYLID 356
+ ++ + P Q + +E ++ LSGG+ RV + DV ++D
Sbjct: 670 TEYLQRGFNLPYQDARKCLGRFGLESHAHTIQICKLSGGQKARVVFAELACREPDVLILD 729
Query: 355 EPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMAT 236
EP+ LD E + I + K VV HD + T
Sbjct: 730 EPTNNLDIESIDALGEAINEY----KGAVIVVSHDARLIT 765
Score = 33.5 bits (73), Expect = 0.88
Identities = 20/69 (28%), Positives = 35/69 (50%)
Frame = -3
Query: 457 EIMDQEVQNLSGGELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAK 278
E+ ++ Q SGG RV+L L + ++DEP+ +LD L A + ++ +
Sbjct: 405 EMQNRPTQKFSGGWRMRVSLARALFMEPTLLMLDEPTNHLD----LNAVIWLNNYLQGWR 460
Query: 277 RTGFVVEHD 251
+T +V HD
Sbjct: 461 KTLLIVSHD 469
>BX000357-6|CAI18563.1| 845|Homo sapiens ATP-binding cassette,
sub-family F (GCN20), member 1 protein.
Length = 845
Score = 40.3 bits (90), Expect = 0.008
Identities = 41/160 (25%), Positives = 70/160 (43%), Gaps = 3/160 (1%)
Frame = -3
Query: 706 DSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLP-QLHISYKPQKISPKSQGLVRSLL 530
DS I ++ G NG GK+T + +L G L P G + +L I + Q+ + + + +
Sbjct: 651 DSRICIV-GPNGVGKSTLLLLLTGKLTPTHGEMRKNHRLKIGFFNQQYAEQLR--MEETP 707
Query: 529 HDKIRDAYIHP-QFLTDVMKPMKIEEIMDQ-EVQNLSGGELQRVALVLCLGKPADVYLID 356
+ ++ + P Q + +E ++ LSGG+ RV + DV ++D
Sbjct: 708 TEYLQRGFNLPYQDARKCLGRFGLESHAHTIQICKLSGGQKARVVFAELACREPDVLILD 767
Query: 355 EPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMAT 236
EP+ LD E + I + K VV HD + T
Sbjct: 768 EPTNNLDIESIDALGEAINEY----KGAVIVVSHDARLIT 803
Score = 33.5 bits (73), Expect = 0.88
Identities = 20/69 (28%), Positives = 35/69 (50%)
Frame = -3
Query: 457 EIMDQEVQNLSGGELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAK 278
E+ ++ Q SGG RV+L L + ++DEP+ +LD L A + ++ +
Sbjct: 443 EMQNRPTQKFSGGWRMRVSLARALFMEPTLLMLDEPTNHLD----LNAVIWLNNYLQGWR 498
Query: 277 RTGFVVEHD 251
+T +V HD
Sbjct: 499 KTLLIVSHD 507
>BC112923-1|AAI12924.1| 845|Homo sapiens ATP-binding cassette,
sub-family F (GCN20), member 1 protein.
Length = 845
Score = 40.3 bits (90), Expect = 0.008
Identities = 41/160 (25%), Positives = 70/160 (43%), Gaps = 3/160 (1%)
Frame = -3
Query: 706 DSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLP-QLHISYKPQKISPKSQGLVRSLL 530
DS I ++ G NG GK+T + +L G L P G + +L I + Q+ + + + +
Sbjct: 651 DSRICIV-GPNGVGKSTLLLLLTGKLTPTHGEMRKNHRLKIGFFNQQYAEQLR--MEETP 707
Query: 529 HDKIRDAYIHP-QFLTDVMKPMKIEEIMDQ-EVQNLSGGELQRVALVLCLGKPADVYLID 356
+ ++ + P Q + +E ++ LSGG+ RV + DV ++D
Sbjct: 708 TEYLQRGFNLPYQDARKCLGRFGLESHAHTIQICKLSGGQKARVVFAELACREPDVLILD 767
Query: 355 EPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMAT 236
EP+ LD E + I + K VV HD + T
Sbjct: 768 EPTNNLDIESIDALGEAINEY----KGAVIVVSHDARLIT 803
Score = 33.5 bits (73), Expect = 0.88
Identities = 20/69 (28%), Positives = 35/69 (50%)
Frame = -3
Query: 457 EIMDQEVQNLSGGELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAK 278
E+ ++ Q SGG RV+L L + ++DEP+ +LD L A + ++ +
Sbjct: 443 EMQNRPTQKFSGGWRMRVSLARALFMEPTLLMLDEPTNHLD----LNAVIWLNNYLQGWR 498
Query: 277 RTGFVVEHD 251
+T +V HD
Sbjct: 499 KTLLIVSHD 507
>BC034488-1|AAH34488.1| 845|Homo sapiens ATP-binding cassette,
sub-family F (GCN20), member 1 protein.
Length = 845
Score = 40.3 bits (90), Expect = 0.008
Identities = 41/160 (25%), Positives = 70/160 (43%), Gaps = 3/160 (1%)
Frame = -3
Query: 706 DSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLP-QLHISYKPQKISPKSQGLVRSLL 530
DS I ++ G NG GK+T + +L G L P G + +L I + Q+ + + + +
Sbjct: 651 DSRICIV-GPNGVGKSTLLLLLTGKLTPTHGEMRKNHRLKIGFFNQQYAEQLR--MEETP 707
Query: 529 HDKIRDAYIHP-QFLTDVMKPMKIEEIMDQ-EVQNLSGGELQRVALVLCLGKPADVYLID 356
+ ++ + P Q + +E ++ LSGG+ RV + DV ++D
Sbjct: 708 TEYLQRGFNLPYQDARKCLGRFGLESHAHTIQICKLSGGQKARVVFAELACREPDVLILD 767
Query: 355 EPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMAT 236
EP+ LD E + I + K VV HD + T
Sbjct: 768 EPTNNLDIESIDALGEAINEY----KGAVIVVSHDARLIT 803
Score = 33.5 bits (73), Expect = 0.88
Identities = 20/69 (28%), Positives = 35/69 (50%)
Frame = -3
Query: 457 EIMDQEVQNLSGGELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAK 278
E+ ++ Q SGG RV+L L + ++DEP+ +LD L A + ++ +
Sbjct: 443 EMQNRPTQKFSGGWRMRVSLARALFMEPTLLMLDEPTNHLD----LNAVIWLNNYLQGWR 498
Query: 277 RTGFVVEHD 251
+T +V HD
Sbjct: 499 KTLLIVSHD 507
>BA000025-75|BAB63325.1| 807|Homo sapiens TNFalpha-inducible
ATP-binding protein protein.
Length = 807
Score = 40.3 bits (90), Expect = 0.008
Identities = 41/160 (25%), Positives = 70/160 (43%), Gaps = 3/160 (1%)
Frame = -3
Query: 706 DSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLP-QLHISYKPQKISPKSQGLVRSLL 530
DS I ++ G NG GK+T + +L G L P G + +L I + Q+ + + + +
Sbjct: 613 DSRICIV-GPNGVGKSTLLLLLTGKLTPTHGEMRKNHRLKIGFFNQQYAEQLR--MEETP 669
Query: 529 HDKIRDAYIHP-QFLTDVMKPMKIEEIMDQ-EVQNLSGGELQRVALVLCLGKPADVYLID 356
+ ++ + P Q + +E ++ LSGG+ RV + DV ++D
Sbjct: 670 TEYLQRGFNLPYQDARKCLGRFGLESHAHTIQICKLSGGQKARVVFAELACREPDVLILD 729
Query: 355 EPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMAT 236
EP+ LD E + I + K VV HD + T
Sbjct: 730 EPTNNLDIESIDALGEAINEY----KGAVIVVSHDARLIT 765
Score = 33.5 bits (73), Expect = 0.88
Identities = 20/69 (28%), Positives = 35/69 (50%)
Frame = -3
Query: 457 EIMDQEVQNLSGGELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAK 278
E+ ++ Q SGG RV+L L + ++DEP+ +LD L A + ++ +
Sbjct: 405 EMQNRPTQKFSGGWRMRVSLARALFMEPTLLMLDEPTNHLD----LNAVIWLNNYLQGWR 460
Query: 277 RTGFVVEHD 251
+T +V HD
Sbjct: 461 KTLLIVSHD 469
>AL662825-7|CAI17837.1| 845|Homo sapiens ATP-binding cassette,
sub-family F (GCN20), member 1 protein.
Length = 845
Score = 40.3 bits (90), Expect = 0.008
Identities = 41/160 (25%), Positives = 70/160 (43%), Gaps = 3/160 (1%)
Frame = -3
Query: 706 DSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLP-QLHISYKPQKISPKSQGLVRSLL 530
DS I ++ G NG GK+T + +L G L P G + +L I + Q+ + + + +
Sbjct: 651 DSRICIV-GPNGVGKSTLLLLLTGKLTPTHGEMRKNHRLKIGFFNQQYAEQLR--MEETP 707
Query: 529 HDKIRDAYIHP-QFLTDVMKPMKIEEIMDQ-EVQNLSGGELQRVALVLCLGKPADVYLID 356
+ ++ + P Q + +E ++ LSGG+ RV + DV ++D
Sbjct: 708 TEYLQRGFNLPYQDARKCLGRFGLESHAHTIQICKLSGGQKARVVFAELACREPDVLILD 767
Query: 355 EPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMAT 236
EP+ LD E + I + K VV HD + T
Sbjct: 768 EPTNNLDIESIDALGEAINEY----KGAVIVVSHDARLIT 803
Score = 33.5 bits (73), Expect = 0.88
Identities = 20/69 (28%), Positives = 35/69 (50%)
Frame = -3
Query: 457 EIMDQEVQNLSGGELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAK 278
E+ ++ Q SGG RV+L L + ++DEP+ +LD L A + ++ +
Sbjct: 443 EMQNRPTQKFSGGWRMRVSLARALFMEPTLLMLDEPTNHLD----LNAVIWLNNYLQGWR 498
Query: 277 RTGFVVEHD 251
+T +V HD
Sbjct: 499 KTLLIVSHD 507
>AL662825-6|CAI17836.1| 807|Homo sapiens ATP-binding cassette,
sub-family F (GCN20), member 1 protein.
Length = 807
Score = 40.3 bits (90), Expect = 0.008
Identities = 41/160 (25%), Positives = 70/160 (43%), Gaps = 3/160 (1%)
Frame = -3
Query: 706 DSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLP-QLHISYKPQKISPKSQGLVRSLL 530
DS I ++ G NG GK+T + +L G L P G + +L I + Q+ + + + +
Sbjct: 613 DSRICIV-GPNGVGKSTLLLLLTGKLTPTHGEMRKNHRLKIGFFNQQYAEQLR--MEETP 669
Query: 529 HDKIRDAYIHP-QFLTDVMKPMKIEEIMDQ-EVQNLSGGELQRVALVLCLGKPADVYLID 356
+ ++ + P Q + +E ++ LSGG+ RV + DV ++D
Sbjct: 670 TEYLQRGFNLPYQDARKCLGRFGLESHAHTIQICKLSGGQKARVVFAELACREPDVLILD 729
Query: 355 EPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMAT 236
EP+ LD E + I + K VV HD + T
Sbjct: 730 EPTNNLDIESIDALGEAINEY----KGAVIVVSHDARLIT 765
Score = 33.5 bits (73), Expect = 0.88
Identities = 20/69 (28%), Positives = 35/69 (50%)
Frame = -3
Query: 457 EIMDQEVQNLSGGELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAK 278
E+ ++ Q SGG RV+L L + ++DEP+ +LD L A + ++ +
Sbjct: 405 EMQNRPTQKFSGGWRMRVSLARALFMEPTLLMLDEPTNHLD----LNAVIWLNNYLQGWR 460
Query: 277 RTGFVVEHD 251
+T +V HD
Sbjct: 461 KTLLIVSHD 469
>AL662800-8|CAI18158.1| 845|Homo sapiens ATP-binding cassette,
sub-family F (GCN20), member 1 protein.
Length = 845
Score = 40.3 bits (90), Expect = 0.008
Identities = 41/160 (25%), Positives = 70/160 (43%), Gaps = 3/160 (1%)
Frame = -3
Query: 706 DSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLP-QLHISYKPQKISPKSQGLVRSLL 530
DS I ++ G NG GK+T + +L G L P G + +L I + Q+ + + + +
Sbjct: 651 DSRICIV-GPNGVGKSTLLLLLTGKLTPTHGEMRKNHRLKIGFFNQQYAEQLR--MEETP 707
Query: 529 HDKIRDAYIHP-QFLTDVMKPMKIEEIMDQ-EVQNLSGGELQRVALVLCLGKPADVYLID 356
+ ++ + P Q + +E ++ LSGG+ RV + DV ++D
Sbjct: 708 TEYLQRGFNLPYQDARKCLGRFGLESHAHTIQICKLSGGQKARVVFAELACREPDVLILD 767
Query: 355 EPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMAT 236
EP+ LD E + I + K VV HD + T
Sbjct: 768 EPTNNLDIESIDALGEAINEY----KGAVIVVSHDARLIT 803
Score = 33.5 bits (73), Expect = 0.88
Identities = 20/69 (28%), Positives = 35/69 (50%)
Frame = -3
Query: 457 EIMDQEVQNLSGGELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAK 278
E+ ++ Q SGG RV+L L + ++DEP+ +LD L A + ++ +
Sbjct: 443 EMQNRPTQKFSGGWRMRVSLARALFMEPTLLMLDEPTNHLD----LNAVIWLNNYLQGWR 498
Query: 277 RTGFVVEHD 251
+T +V HD
Sbjct: 499 KTLLIVSHD 507
>AL662800-7|CAI18159.1| 807|Homo sapiens ATP-binding cassette,
sub-family F (GCN20), member 1 protein.
Length = 807
Score = 40.3 bits (90), Expect = 0.008
Identities = 41/160 (25%), Positives = 70/160 (43%), Gaps = 3/160 (1%)
Frame = -3
Query: 706 DSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLP-QLHISYKPQKISPKSQGLVRSLL 530
DS I ++ G NG GK+T + +L G L P G + +L I + Q+ + + + +
Sbjct: 613 DSRICIV-GPNGVGKSTLLLLLTGKLTPTHGEMRKNHRLKIGFFNQQYAEQLR--MEETP 669
Query: 529 HDKIRDAYIHP-QFLTDVMKPMKIEEIMDQ-EVQNLSGGELQRVALVLCLGKPADVYLID 356
+ ++ + P Q + +E ++ LSGG+ RV + DV ++D
Sbjct: 670 TEYLQRGFNLPYQDARKCLGRFGLESHAHTIQICKLSGGQKARVVFAELACREPDVLILD 729
Query: 355 EPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMAT 236
EP+ LD E + I + K VV HD + T
Sbjct: 730 EPTNNLDIESIDALGEAINEY----KGAVIVVSHDARLIT 765
Score = 33.5 bits (73), Expect = 0.88
Identities = 20/69 (28%), Positives = 35/69 (50%)
Frame = -3
Query: 457 EIMDQEVQNLSGGELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAK 278
E+ ++ Q SGG RV+L L + ++DEP+ +LD L A + ++ +
Sbjct: 405 EMQNRPTQKFSGGWRMRVSLARALFMEPTLLMLDEPTNHLD----LNAVIWLNNYLQGWR 460
Query: 277 RTGFVVEHD 251
+T +V HD
Sbjct: 461 KTLLIVSHD 469
>AK128516-1|BAC87475.1| 788|Homo sapiens protein ( Homo sapiens
cDNA FLJ46673 fis, clone TRACH3009061, weakly similar
to ATP-binding cassette, sub-family A, member 1. ).
Length = 788
Score = 40.3 bits (90), Expect = 0.008
Identities = 41/142 (28%), Positives = 63/142 (44%), Gaps = 20/142 (14%)
Frame = -3
Query: 700 EILVLLGENGTGKTTFIRMLAGNLEPDEGS-------GQLPQLH--------ISYKPQK- 569
E LLG NG GK+T +ML G + G G L I Y PQ+
Sbjct: 478 ECFGLLGVNGAGKSTTFKMLNGEVSLTSGHAIIRTPMGDAVDLSSAGTAGVLIGYCPQQD 537
Query: 568 -ISPKSQGLVRSLLHDKIRDA--YIHPQFLTDVMKPMKIEEIMDQEVQNLSGGELQRVAL 398
+ G + +R P+ D+++ + +E D+ V SGG ++++
Sbjct: 538 ALDELLTGWEHLYYYCSLRGIPRQCIPEVAGDLIRRLHLEAHADKPVATYSGGTKRKLST 597
Query: 397 VLCL-GKPADVYLIDEPSAYLD 335
L L GKP D+ L+DEPS+ +D
Sbjct: 598 ALALVGKP-DILLLDEPSSGMD 618
>AF027302-1|AAC70891.1| 807|Homo sapiens TNF-alpha stimulated ABC
protein protein.
Length = 807
Score = 40.3 bits (90), Expect = 0.008
Identities = 41/160 (25%), Positives = 70/160 (43%), Gaps = 3/160 (1%)
Frame = -3
Query: 706 DSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLP-QLHISYKPQKISPKSQGLVRSLL 530
DS I ++ G NG GK+T + +L G L P G + +L I + Q+ + + + +
Sbjct: 613 DSRICIV-GPNGVGKSTLLLLLTGKLTPTHGEMRKNHRLKIGFFNQQYAEQLR--MEETP 669
Query: 529 HDKIRDAYIHP-QFLTDVMKPMKIEEIMDQ-EVQNLSGGELQRVALVLCLGKPADVYLID 356
+ ++ + P Q + +E ++ LSGG+ RV + DV ++D
Sbjct: 670 TEYLQRGFNLPYQDARKCLGRFGLESHAHTIQICKLSGGQKARVVFAELACREPDVLILD 729
Query: 355 EPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMAT 236
EP+ LD E + I + K VV HD + T
Sbjct: 730 EPTNNLDIESIDALGEAINEY----KGAVIVVSHDARLIT 765
Score = 33.5 bits (73), Expect = 0.88
Identities = 20/69 (28%), Positives = 35/69 (50%)
Frame = -3
Query: 457 EIMDQEVQNLSGGELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAK 278
E+ ++ Q SGG RV+L L + ++DEP+ +LD L A + ++ +
Sbjct: 405 EMQNRPTQKFSGGWRMRVSLARALFMEPTLLMLDEPTNHLD----LNAVIWLNNYLQGWR 460
Query: 277 RTGFVVEHD 251
+T +V HD
Sbjct: 461 KTLLIVSHD 469
>AF022853-4|AAB83981.1| 1456|Homo sapiens multidrug resistance
protein protein.
Length = 1456
Score = 40.3 bits (90), Expect = 0.008
Identities = 34/105 (32%), Positives = 51/105 (48%), Gaps = 3/105 (2%)
Frame = -3
Query: 433 NLSGGELQRVALVLCLGKPADVYLIDEPSAYLDSE-QRLVAAKVIKRFILHAKRTGFVVE 257
NLSGG+ QRV+L + AD+YL D+P + +D+ + + VI + +T +V
Sbjct: 692 NLSGGQKQRVSLARAVYSNADIYLFDDPLSAVDAHVGKHIFENVIGPKGMLKNKTRILVT 751
Query: 256 HDFIMATYL--ADRVIVFEGTPSSNATAHAPQSLLNGMNKFLELL 128
H +YL D +IV G S ++ Q LL F E L
Sbjct: 752 HSM---SYLPQVDVIIVMSGGKISEMGSY--QELLARDGAFAEFL 791
>AB209564-1|BAD92801.1| 593|Homo sapiens ATP-binding cassette,
sub-family F, member 1 variant protein.
Length = 593
Score = 40.3 bits (90), Expect = 0.008
Identities = 41/160 (25%), Positives = 70/160 (43%), Gaps = 3/160 (1%)
Frame = -3
Query: 706 DSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLP-QLHISYKPQKISPKSQGLVRSLL 530
DS I ++ G NG GK+T + +L G L P G + +L I + Q+ + + + +
Sbjct: 399 DSRICIV-GPNGVGKSTLLLLLTGKLTPTHGEMRKNHRLKIGFFNQQYAEQLR--MEETP 455
Query: 529 HDKIRDAYIHP-QFLTDVMKPMKIEEIMDQ-EVQNLSGGELQRVALVLCLGKPADVYLID 356
+ ++ + P Q + +E ++ LSGG+ RV + DV ++D
Sbjct: 456 TEYLQRGFNLPYQDARKCLGRFGLESHAHTIQICKLSGGQKARVVFAELACREPDVLILD 515
Query: 355 EPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMAT 236
EP+ LD E + I + K VV HD + T
Sbjct: 516 EPTNNLDIESIDALGEAINEY----KGAVIVVSHDARLIT 551
Score = 33.5 bits (73), Expect = 0.88
Identities = 20/69 (28%), Positives = 35/69 (50%)
Frame = -3
Query: 457 EIMDQEVQNLSGGELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAK 278
E+ ++ Q SGG RV+L L + ++DEP+ +LD L A + ++ +
Sbjct: 191 EMQNRPTQKFSGGWRMRVSLARALFMEPTLLMLDEPTNHLD----LNAVIWLNNYLQGWR 246
Query: 277 RTGFVVEHD 251
+T +V HD
Sbjct: 247 KTLLIVSHD 255
>AB202093-1|BAE78612.1| 807|Homo sapiens ATP-binding cassette,
sub-family F (GCN20), member 1 protein.
Length = 807
Score = 40.3 bits (90), Expect = 0.008
Identities = 41/160 (25%), Positives = 70/160 (43%), Gaps = 3/160 (1%)
Frame = -3
Query: 706 DSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLP-QLHISYKPQKISPKSQGLVRSLL 530
DS I ++ G NG GK+T + +L G L P G + +L I + Q+ + + + +
Sbjct: 613 DSRICIV-GPNGVGKSTLLLLLTGKLTPTHGEMRKNHRLKIGFFNQQYAEQLR--MEETP 669
Query: 529 HDKIRDAYIHP-QFLTDVMKPMKIEEIMDQ-EVQNLSGGELQRVALVLCLGKPADVYLID 356
+ ++ + P Q + +E ++ LSGG+ RV + DV ++D
Sbjct: 670 TEYLQRGFNLPYQDARKCLGRFGLESHAHTIQICKLSGGQKARVVFAELACREPDVLILD 729
Query: 355 EPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMAT 236
EP+ LD E + I + K VV HD + T
Sbjct: 730 EPTNNLDIESIDALGEAINEY----KGAVIVVSHDARLIT 765
Score = 33.5 bits (73), Expect = 0.88
Identities = 20/69 (28%), Positives = 35/69 (50%)
Frame = -3
Query: 457 EIMDQEVQNLSGGELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAK 278
E+ ++ Q SGG RV+L L + ++DEP+ +LD L A + ++ +
Sbjct: 405 EMQNRPTQKFSGGWRMRVSLARALFMEPTLLMLDEPTNHLD----LNAVIWLNNYLQGWR 460
Query: 277 RTGFVVEHD 251
+T +V HD
Sbjct: 461 KTLLIVSHD 469
>AB103602-1|BAF31263.1| 807|Homo sapiens ABC50 protein protein.
Length = 807
Score = 40.3 bits (90), Expect = 0.008
Identities = 41/160 (25%), Positives = 70/160 (43%), Gaps = 3/160 (1%)
Frame = -3
Query: 706 DSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLP-QLHISYKPQKISPKSQGLVRSLL 530
DS I ++ G NG GK+T + +L G L P G + +L I + Q+ + + + +
Sbjct: 613 DSRICIV-GPNGVGKSTLLLLLTGKLTPTHGEMRKNHRLKIGFFNQQYAEQLR--MEETP 669
Query: 529 HDKIRDAYIHP-QFLTDVMKPMKIEEIMDQ-EVQNLSGGELQRVALVLCLGKPADVYLID 356
+ ++ + P Q + +E ++ LSGG+ RV + DV ++D
Sbjct: 670 TEYLQRGFNLPYQDARKCLGRFGLESHAHTIQICKLSGGQKARVVFAELACREPDVLILD 729
Query: 355 EPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMAT 236
EP+ LD E + I + K VV HD + T
Sbjct: 730 EPTNNLDIESIDALGEAINEY----KGAVIVVSHDARLIT 765
Score = 33.5 bits (73), Expect = 0.88
Identities = 20/69 (28%), Positives = 35/69 (50%)
Frame = -3
Query: 457 EIMDQEVQNLSGGELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAK 278
E+ ++ Q SGG RV+L L + ++DEP+ +LD L A + ++ +
Sbjct: 405 EMQNRPTQKFSGGWRMRVSLARALFMEPTLLMLDEPTNHLD----LNAVIWLNNYLQGWR 460
Query: 277 RTGFVVEHD 251
+T +V HD
Sbjct: 461 KTLLIVSHD 469
>AB088096-1|BAC54928.1| 807|Homo sapiens ATP-binding cassette,
sub-family F (GCN20), member 1 protein.
Length = 807
Score = 40.3 bits (90), Expect = 0.008
Identities = 41/160 (25%), Positives = 70/160 (43%), Gaps = 3/160 (1%)
Frame = -3
Query: 706 DSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQLP-QLHISYKPQKISPKSQGLVRSLL 530
DS I ++ G NG GK+T + +L G L P G + +L I + Q+ + + + +
Sbjct: 613 DSRICIV-GPNGVGKSTLLLLLTGKLTPTHGEMRKNHRLKIGFFNQQYAEQLR--MEETP 669
Query: 529 HDKIRDAYIHP-QFLTDVMKPMKIEEIMDQ-EVQNLSGGELQRVALVLCLGKPADVYLID 356
+ ++ + P Q + +E ++ LSGG+ RV + DV ++D
Sbjct: 670 TEYLQRGFNLPYQDARKCLGRFGLESHAHTIQICKLSGGQKARVVFAELACREPDVLILD 729
Query: 355 EPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMAT 236
EP+ LD E + I + K VV HD + T
Sbjct: 730 EPTNNLDIESIDALGEAINEY----KGAVIVVSHDARLIT 765
Score = 33.5 bits (73), Expect = 0.88
Identities = 20/69 (28%), Positives = 35/69 (50%)
Frame = -3
Query: 457 EIMDQEVQNLSGGELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAK 278
E+ ++ Q SGG RV+L L + ++DEP+ +LD L A + ++ +
Sbjct: 405 EMQNRPTQKFSGGWRMRVSLARALFMEPTLLMLDEPTNHLD----LNAVIWLNNYLQGWR 460
Query: 277 RTGFVVEHD 251
+T +V HD
Sbjct: 461 KTLLIVSHD 469
>X91249-1|CAA62631.1| 674|Homo sapiens white protein.
Length = 674
Score = 39.5 bits (88), Expect = 0.013
Identities = 36/160 (22%), Positives = 75/160 (46%), Gaps = 15/160 (9%)
Frame = -3
Query: 733 LRVMPGEFSDSEILVLLGENGTGKTTFIRMLAGNLEPD-EGSGQLPQLHISYKP-QKISP 560
L+ + G+F+ E++ ++G +G GK+T + +LAG E +G+ + L + +K+S
Sbjct: 97 LKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVSC 156
Query: 559 KSQGLVRSLLHDKIRDAYI-------------HPQFLTDVMKPMKIEEIMDQEVQNLSGG 419
L H +++A + + + +++ + + + +LSGG
Sbjct: 157 YIMQDDMLLPHLTVQEAMMVSAHLKLQEKDEGRREMVKEILTALGLLSCANTRTGSLSGG 216
Query: 418 ELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIK 299
+ +R+A+ L L V DEP++ LDS ++K
Sbjct: 217 QRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMK 256
>X87344-5|CAA60785.1| 748|Homo sapiens TAP1 protein.
Length = 748
Score = 39.5 bits (88), Expect = 0.013
Identities = 46/189 (24%), Positives = 83/189 (43%), Gaps = 23/189 (12%)
Frame = -3
Query: 700 EILVLLGENGTGKTTFIRMLAGNLEPDEGS----GQ-LPQ-----LH-----ISYKPQKI 566
E+ L+G NG+GK+T +L +P G G+ LPQ LH + +PQ
Sbjct: 532 EVTALVGPNGSGKSTVAALLQNLYQPTGGQLLLDGKPLPQYEHRYLHRQVAAVGQEPQVF 591
Query: 565 SPKSQ-----GLVRSLLHDKIRDAYIHP---QFLTDVMKPMKIEEIMDQEVQNLSGGELQ 410
Q GL + ++I A + F++ + P + +D+ LSGG+ Q
Sbjct: 592 GRSLQENIAYGLTQKPTMEEITAAAVKSGAHSFISGL--PQGYDTEVDEAGSQLSGGQRQ 649
Query: 409 RVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMATYL 230
VAL L + V ++D+ ++ LD+ +L +++ R+ ++ +
Sbjct: 650 AVALARALIRKPCVLILDDATSALDANSQLQVEQLLYESPERYSRSVLLITQHLSLVEQ- 708
Query: 229 ADRVIVFEG 203
AD ++ EG
Sbjct: 709 ADHILFLEG 717
>X66401-2|CAA47025.1| 748|Homo sapiens ABC-transporter protein.
Length = 748
Score = 39.5 bits (88), Expect = 0.013
Identities = 46/189 (24%), Positives = 83/189 (43%), Gaps = 23/189 (12%)
Frame = -3
Query: 700 EILVLLGENGTGKTTFIRMLAGNLEPDEGS----GQ-LPQ-----LH-----ISYKPQKI 566
E+ L+G NG+GK+T +L +P G G+ LPQ LH + +PQ
Sbjct: 532 EVTALVGPNGSGKSTVAALLQNLYQPTGGQLLLDGKPLPQYEHRYLHRQVAAVGQEPQVF 591
Query: 565 SPKSQ-----GLVRSLLHDKIRDAYIHP---QFLTDVMKPMKIEEIMDQEVQNLSGGELQ 410
Q GL + ++I A + F++ + P + +D+ LSGG+ Q
Sbjct: 592 GRSLQENIAYGLTQKPTMEEITAAAVKSGAHSFISGL--PQGYDTEVDEAGSQLSGGQRQ 649
Query: 409 RVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMATYL 230
VAL L + V ++D+ ++ LD+ +L +++ R+ ++ +
Sbjct: 650 AVALARALIRKPCVLILDDATSALDANSQLQVEQLLYESPERYSRSVLLITQHLSLVEQ- 708
Query: 229 ADRVIVFEG 203
AD ++ EG
Sbjct: 709 ADHILFLEG 717
>X57522-1|CAA40741.1| 808|Homo sapiens peptide transporter protein.
Length = 808
Score = 39.5 bits (88), Expect = 0.013
Identities = 46/189 (24%), Positives = 83/189 (43%), Gaps = 23/189 (12%)
Frame = -3
Query: 700 EILVLLGENGTGKTTFIRMLAGNLEPDEGS----GQ-LPQ-----LH-----ISYKPQKI 566
E+ L+G NG+GK+T +L +P G G+ LPQ LH + +PQ
Sbjct: 592 EVTALVGPNGSGKSTVAALLQNLYQPTGGQLLLDGKPLPQYEHRYLHRQVAAVGQEPQVF 651
Query: 565 SPKSQ-----GLVRSLLHDKIRDAYIHP---QFLTDVMKPMKIEEIMDQEVQNLSGGELQ 410
Q GL + ++I A + F++ + P + +D+ LSGG+ Q
Sbjct: 652 GRSLQENIAYGLTQKPTMEEITAAAVKSGAHSFISGL--PQGYDTEVDEAGSQLSGGQRQ 709
Query: 409 RVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMATYL 230
VAL L + V ++D+ ++ LD+ +L +++ R+ ++ +
Sbjct: 710 AVALARALIRKPCVLILDDATSALDANSQLQVEQLLYESPERYSRSVLLITQHLSLVEQ- 768
Query: 229 ADRVIVFEG 203
AD ++ EG
Sbjct: 769 ADHILFLEG 777
>U34919-1|AAC51098.1| 638|Homo sapiens white homolog protein.
Length = 638
Score = 39.5 bits (88), Expect = 0.013
Identities = 36/160 (22%), Positives = 75/160 (46%), Gaps = 15/160 (9%)
Frame = -3
Query: 733 LRVMPGEFSDSEILVLLGENGTGKTTFIRMLAGNLEPD-EGSGQLPQLHISYKP-QKISP 560
L+ + G+F+ E++ ++G +G GK+T + +LAG E +G+ + L + +K+S
Sbjct: 61 LKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVSC 120
Query: 559 KSQGLVRSLLHDKIRDAYI-------------HPQFLTDVMKPMKIEEIMDQEVQNLSGG 419
L H +++A + + + +++ + + + +LSGG
Sbjct: 121 YIMQDDMLLPHLTVQEAMMVSAHLKLQEKDEGRREMVKEILTALGLLSCANTRTGSLSGG 180
Query: 418 ELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIK 299
+ +R+A+ L L V DEP++ LDS ++K
Sbjct: 181 QRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMK 220
>U18237-1|AAA84438.1| 229|Homo sapiens ATP-binding cassette protein
protein.
Length = 229
Score = 39.5 bits (88), Expect = 0.013
Identities = 22/73 (30%), Positives = 39/73 (53%)
Frame = -3
Query: 472 PMKIEEIMDQEVQNLSGGELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRF 293
P + ++ ++ LSGG+ QR+A+ L K + L+DE ++ LD+E + + + R
Sbjct: 111 PPRFNTVVGEKGVLLSGGQKQRIAIARALLKNPKILLLDEATSALDAENEYLVQEALDR- 169
Query: 292 ILHAKRTGFVVEH 254
L RT V+ H
Sbjct: 170 -LMDGRTVLVIAH 181
>L21208-1|AAC12906.1| 748|Homo sapiens peptide transporter protein.
Length = 748
Score = 39.5 bits (88), Expect = 0.013
Identities = 46/189 (24%), Positives = 83/189 (43%), Gaps = 23/189 (12%)
Frame = -3
Query: 700 EILVLLGENGTGKTTFIRMLAGNLEPDEGS----GQ-LPQ-----LH-----ISYKPQKI 566
E+ L+G NG+GK+T +L +P G G+ LPQ LH + +PQ
Sbjct: 532 EVTALVGPNGSGKSTVAALLQNLYQPTGGQLLLDGKPLPQYEHRYLHRQVAAVGQEPQVF 591
Query: 565 SPKSQ-----GLVRSLLHDKIRDAYIHP---QFLTDVMKPMKIEEIMDQEVQNLSGGELQ 410
Q GL + ++I A + F++ + P + +D+ LSGG+ Q
Sbjct: 592 GRSLQENIAYGLTQKPTMEEITAAAVKSGAHSFISGL--PQGYDTEVDEAGSQLSGGQRQ 649
Query: 409 RVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMATYL 230
VAL L + V ++D+ ++ LD+ +L +++ R+ ++ +
Sbjct: 650 AVALARALIRKPCVLILDDATSALDANSQLQVEQLLYESPERYSRSVLLITQHLSLVEQ- 708
Query: 229 ADRVIVFEG 203
AD ++ EG
Sbjct: 709 ADHILFLEG 717
>L21204-1|AAC12902.1| 748|Homo sapiens peptide transporter protein.
Length = 748
Score = 39.5 bits (88), Expect = 0.013
Identities = 46/189 (24%), Positives = 83/189 (43%), Gaps = 23/189 (12%)
Frame = -3
Query: 700 EILVLLGENGTGKTTFIRMLAGNLEPDEGS----GQ-LPQ-----LH-----ISYKPQKI 566
E+ L+G NG+GK+T +L +P G G+ LPQ LH + +PQ
Sbjct: 532 EVTALVGPNGSGKSTVAALLQNLYQPTGGQLLLDGKPLPQYEHRYLHRQVAAVGQEPQVF 591
Query: 565 SPKSQ-----GLVRSLLHDKIRDAYIHP---QFLTDVMKPMKIEEIMDQEVQNLSGGELQ 410
Q GL + ++I A + F++ + P + +D+ LSGG+ Q
Sbjct: 592 GRSLQENIAYGLTQKPTMEEITAAAVKSGAHSFISGL--PQGYDTEVDEAGSQLSGGQRQ 649
Query: 409 RVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMATYL 230
VAL L + V ++D+ ++ LD+ +L +++ R+ ++ +
Sbjct: 650 AVALARALIRKPCVLILDDATSALDANSQLQVEQLLYESPERYSRSVLLITQHLSLVEQ- 708
Query: 229 ADRVIVFEG 203
AD ++ EG
Sbjct: 709 ADHILFLEG 717
>BX088556-4|CAM26263.1| 808|Homo sapiens transporter 1 ATP-binding
cassette sub-family B (MDR/TAP) protein.
Length = 808
Score = 39.5 bits (88), Expect = 0.013
Identities = 46/189 (24%), Positives = 83/189 (43%), Gaps = 23/189 (12%)
Frame = -3
Query: 700 EILVLLGENGTGKTTFIRMLAGNLEPDEGS----GQ-LPQ-----LH-----ISYKPQKI 566
E+ L+G NG+GK+T +L +P G G+ LPQ LH + +PQ
Sbjct: 592 EVTALVGPNGSGKSTVAALLQNLYQPTGGQLLLDGKPLPQYEHRYLHRQVAAVGQEPQVF 651
Query: 565 SPKSQ-----GLVRSLLHDKIRDAYIHP---QFLTDVMKPMKIEEIMDQEVQNLSGGELQ 410
Q GL + ++I A + F++ + P + +D+ LSGG+ Q
Sbjct: 652 GRSLQENIAYGLTQKPTMEEITAAAVKSGAHSFISGL--PQGYDTEVDEAGSQLSGGQRQ 709
Query: 409 RVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMATYL 230
VAL L + V ++D+ ++ LD+ +L +++ R+ ++ +
Sbjct: 710 AVALARALIRKPCVLILDDATSALDANSQLQVEQLLYESPERYSRSVLLITQHLSLVEQ- 768
Query: 229 ADRVIVFEG 203
AD ++ EG
Sbjct: 769 ADHILFLEG 777
>BC029158-1|AAH29158.2| 666|Homo sapiens ATP-binding cassette,
sub-family G (WHITE), member 1 protein.
Length = 666
Score = 39.5 bits (88), Expect = 0.013
Identities = 36/160 (22%), Positives = 75/160 (46%), Gaps = 15/160 (9%)
Frame = -3
Query: 733 LRVMPGEFSDSEILVLLGENGTGKTTFIRMLAGNLEPD-EGSGQLPQLHISYKP-QKISP 560
L+ + G+F+ E++ ++G +G GK+T + +LAG E +G+ + L + +K+S
Sbjct: 101 LKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVSC 160
Query: 559 KSQGLVRSLLHDKIRDAYI-------------HPQFLTDVMKPMKIEEIMDQEVQNLSGG 419
L H +++A + + + +++ + + + +LSGG
Sbjct: 161 YIMQDDMLLPHLTVQEAMMVSAHLKLQEKDEGRREMVKEILTALGLLSCANTRTGSLSGG 220
Query: 418 ELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIK 299
+ +R+A+ L L V DEP++ LDS ++K
Sbjct: 221 QRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMK 260
>BC014081-1|AAH14081.1| 808|Homo sapiens transporter 1, ATP-binding
cassette, sub-family B (MDR/TAP) protein.
Length = 808
Score = 39.5 bits (88), Expect = 0.013
Identities = 46/189 (24%), Positives = 83/189 (43%), Gaps = 23/189 (12%)
Frame = -3
Query: 700 EILVLLGENGTGKTTFIRMLAGNLEPDEGS----GQ-LPQ-----LH-----ISYKPQKI 566
E+ L+G NG+GK+T +L +P G G+ LPQ LH + +PQ
Sbjct: 592 EVTALVGPNGSGKSTVAALLQNLYQPTGGQLLLDGKPLPQYEHRYLHRQVAAVGQEPQVF 651
Query: 565 SPKSQ-----GLVRSLLHDKIRDAYIHP---QFLTDVMKPMKIEEIMDQEVQNLSGGELQ 410
Q GL + ++I A + F++ + P + +D+ LSGG+ Q
Sbjct: 652 GRSLQENIAYGLTQKPTMEEITAAAVKSGAHSFISGL--PQGYDTEVDEAGSQLSGGQRQ 709
Query: 409 RVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMATYL 230
VAL L + V ++D+ ++ LD+ +L +++ R+ ++ +
Sbjct: 710 AVALARALIRKPCVLILDDATSALDANSQLQVEQLLYESPERYSRSVLLITQHLSLVEQ- 768
Query: 229 ADRVIVFEG 203
AD ++ EG
Sbjct: 769 ADHILFLEG 777
>AY048757-1|AAL06598.1| 785|Homo sapiens ATP-binding cassette
transporter G1 protein.
Length = 785
Score = 39.5 bits (88), Expect = 0.013
Identities = 36/160 (22%), Positives = 75/160 (46%), Gaps = 15/160 (9%)
Frame = -3
Query: 733 LRVMPGEFSDSEILVLLGENGTGKTTFIRMLAGNLEPD-EGSGQLPQLHISYKP-QKISP 560
L+ + G+F+ E++ ++G +G GK+T + +LAG E +G+ + L + +K+S
Sbjct: 208 LKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVSC 267
Query: 559 KSQGLVRSLLHDKIRDAYI-------------HPQFLTDVMKPMKIEEIMDQEVQNLSGG 419
L H +++A + + + +++ + + + +LSGG
Sbjct: 268 YIMQDDMLLPHLTVQEAMMVSAHLKLQEKDEGRREMVKEILTALGLLSCANTRTGSLSGG 327
Query: 418 ELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIK 299
+ +R+A+ L L V DEP++ LDS ++K
Sbjct: 328 QRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMK 367
>AP001746-1|BAA95530.1| 674|Homo sapiens white protein homolog
(ATP-binding cassette transporter 8) protein.
Length = 674
Score = 39.5 bits (88), Expect = 0.013
Identities = 36/160 (22%), Positives = 75/160 (46%), Gaps = 15/160 (9%)
Frame = -3
Query: 733 LRVMPGEFSDSEILVLLGENGTGKTTFIRMLAGNLEPD-EGSGQLPQLHISYKP-QKISP 560
L+ + G+F+ E++ ++G +G GK+T + +LAG E +G+ + L + +K+S
Sbjct: 97 LKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVSC 156
Query: 559 KSQGLVRSLLHDKIRDAYI-------------HPQFLTDVMKPMKIEEIMDQEVQNLSGG 419
L H +++A + + + +++ + + + +LSGG
Sbjct: 157 YIMQDDMLLPHLTVQEAMMVSAHLKLQEKDEGRREMVKEILTALGLLSCANTRTGSLSGG 216
Query: 418 ELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIK 299
+ +R+A+ L L V DEP++ LDS ++K
Sbjct: 217 QRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMK 256
>AL935043-6|CAI18626.1| 808|Homo sapiens transporter 1, ATP-binding
cassette, sub-family Bpha protein.
Length = 808
Score = 39.5 bits (88), Expect = 0.013
Identities = 46/189 (24%), Positives = 83/189 (43%), Gaps = 23/189 (12%)
Frame = -3
Query: 700 EILVLLGENGTGKTTFIRMLAGNLEPDEGS----GQ-LPQ-----LH-----ISYKPQKI 566
E+ L+G NG+GK+T +L +P G G+ LPQ LH + +PQ
Sbjct: 592 EVTALVGPNGSGKSTVAALLQNLYQPTGGQLLLDGKPLPQYEHRYLHRQVAAVGQEPQVF 651
Query: 565 SPKSQ-----GLVRSLLHDKIRDAYIHP---QFLTDVMKPMKIEEIMDQEVQNLSGGELQ 410
Q GL + ++I A + F++ + P + +D+ LSGG+ Q
Sbjct: 652 GRSLQENIAYGLTQKPTMEEITAAAVKSGAHSFISGL--PQGYDTEVDEAGSQLSGGQRQ 709
Query: 409 RVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMATYL 230
VAL L + V ++D+ ++ LD+ +L +++ R+ ++ +
Sbjct: 710 AVALARALIRKPCVLILDDATSALDANSQLQVEQLLYESPERYSRSVLLITQHLSLVEQ- 768
Query: 229 ADRVIVFEG 203
AD ++ EG
Sbjct: 769 ADHILFLEG 777
>AL671681-12|CAI17714.1| 808|Homo sapiens transporter 1, ATP-binding
cassette, sub-family Be, 9 (large multifunctional pe
protein.
Length = 808
Score = 39.5 bits (88), Expect = 0.013
Identities = 46/189 (24%), Positives = 83/189 (43%), Gaps = 23/189 (12%)
Frame = -3
Query: 700 EILVLLGENGTGKTTFIRMLAGNLEPDEGS----GQ-LPQ-----LH-----ISYKPQKI 566
E+ L+G NG+GK+T +L +P G G+ LPQ LH + +PQ
Sbjct: 592 EVTALVGPNGSGKSTVAALLQNLYQPTGGQLLLDGKPLPQYEHRYLHRQVAAVGQEPQVF 651
Query: 565 SPKSQ-----GLVRSLLHDKIRDAYIHP---QFLTDVMKPMKIEEIMDQEVQNLSGGELQ 410
Q GL + ++I A + F++ + P + +D+ LSGG+ Q
Sbjct: 652 GRSLQENIAYGLTQKPTMEEITAAAVKSGAHSFISGL--PQGYDTEVDEAGSQLSGGQRQ 709
Query: 409 RVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMATYL 230
VAL L + V ++D+ ++ LD+ +L +++ R+ ++ +
Sbjct: 710 AVALARALIRKPCVLILDDATSALDANSQLQVEQLLYESPERYSRSVLLITQHLSLVEQ- 768
Query: 229 ADRVIVFEG 203
AD ++ EG
Sbjct: 769 ADHILFLEG 777
>AL669918-8|CAI18140.1| 808|Homo sapiens transporter 1, ATP-binding
cassette, sub-family Bpha protein.
Length = 808
Score = 39.5 bits (88), Expect = 0.013
Identities = 46/189 (24%), Positives = 83/189 (43%), Gaps = 23/189 (12%)
Frame = -3
Query: 700 EILVLLGENGTGKTTFIRMLAGNLEPDEGS----GQ-LPQ-----LH-----ISYKPQKI 566
E+ L+G NG+GK+T +L +P G G+ LPQ LH + +PQ
Sbjct: 592 EVTALVGPNGSGKSTVAALLQNLYQPTGGQLLLDGKPLPQYEHRYLHRQVAAVGQEPQVF 651
Query: 565 SPKSQ-----GLVRSLLHDKIRDAYIHP---QFLTDVMKPMKIEEIMDQEVQNLSGGELQ 410
Q GL + ++I A + F++ + P + +D+ LSGG+ Q
Sbjct: 652 GRSLQENIAYGLTQKPTMEEITAAAVKSGAHSFISGL--PQGYDTEVDEAGSQLSGGQRQ 709
Query: 409 RVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMATYL 230
VAL L + V ++D+ ++ LD+ +L +++ R+ ++ +
Sbjct: 710 AVALARALIRKPCVLILDDATSALDANSQLQVEQLLYESPERYSRSVLLITQHLSLVEQ- 768
Query: 229 ADRVIVFEG 203
AD ++ EG
Sbjct: 769 ADHILFLEG 777
>AJ289137-1|CAC00730.1| 674|Homo sapiens ATP-binding cassette
transporter, sub-family G member 1 protein.
Length = 674
Score = 39.5 bits (88), Expect = 0.013
Identities = 36/160 (22%), Positives = 75/160 (46%), Gaps = 15/160 (9%)
Frame = -3
Query: 733 LRVMPGEFSDSEILVLLGENGTGKTTFIRMLAGNLEPD-EGSGQLPQLHISYKP-QKISP 560
L+ + G+F+ E++ ++G +G GK+T + +LAG E +G+ + L + +K+S
Sbjct: 97 LKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVSC 156
Query: 559 KSQGLVRSLLHDKIRDAYI-------------HPQFLTDVMKPMKIEEIMDQEVQNLSGG 419
L H +++A + + + +++ + + + +LSGG
Sbjct: 157 YIMQDDMLLPHLTVQEAMMVSAHLKLQEKDEGRREMVKEILTALGLLSCANTRTGSLSGG 216
Query: 418 ELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIK 299
+ +R+A+ L L V DEP++ LDS ++K
Sbjct: 217 QRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMK 256
>AF323664-1|AAK28842.1| 677|Homo sapiens ATP-binding cassette
transporter G1 variant V protein.
Length = 677
Score = 39.5 bits (88), Expect = 0.013
Identities = 36/160 (22%), Positives = 75/160 (46%), Gaps = 15/160 (9%)
Frame = -3
Query: 733 LRVMPGEFSDSEILVLLGENGTGKTTFIRMLAGNLEPD-EGSGQLPQLHISYKP-QKISP 560
L+ + G+F+ E++ ++G +G GK+T + +LAG E +G+ + L + +K+S
Sbjct: 112 LKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVSC 171
Query: 559 KSQGLVRSLLHDKIRDAYI-------------HPQFLTDVMKPMKIEEIMDQEVQNLSGG 419
L H +++A + + + +++ + + + +LSGG
Sbjct: 172 YIMQDDMLLPHLTVQEAMMVSAHLKLQEKDEGRREMVKEILTALGLLSCANTRTGSLSGG 231
Query: 418 ELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIK 299
+ +R+A+ L L V DEP++ LDS ++K
Sbjct: 232 QRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMK 271
>AF323663-1|AAK28841.1| 662|Homo sapiens ATP-binding cassette
transporter G1 variant IV protein.
Length = 662
Score = 39.5 bits (88), Expect = 0.013
Identities = 36/160 (22%), Positives = 75/160 (46%), Gaps = 15/160 (9%)
Frame = -3
Query: 733 LRVMPGEFSDSEILVLLGENGTGKTTFIRMLAGNLEPD-EGSGQLPQLHISYKP-QKISP 560
L+ + G+F+ E++ ++G +G GK+T + +LAG E +G+ + L + +K+S
Sbjct: 97 LKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVSC 156
Query: 559 KSQGLVRSLLHDKIRDAYI-------------HPQFLTDVMKPMKIEEIMDQEVQNLSGG 419
L H +++A + + + +++ + + + +LSGG
Sbjct: 157 YIMQDDMLLPHLTVQEAMMVSAHLKLQEKDEGRREMVKEILTALGLLSCANTRTGSLSGG 216
Query: 418 ELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIK 299
+ +R+A+ L L V DEP++ LDS ++K
Sbjct: 217 QRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMK 256
>AF323662-1|AAK28840.1| 663|Homo sapiens ATP-binding cassette
transporter G1 variant III protein.
Length = 663
Score = 39.5 bits (88), Expect = 0.013
Identities = 36/160 (22%), Positives = 75/160 (46%), Gaps = 15/160 (9%)
Frame = -3
Query: 733 LRVMPGEFSDSEILVLLGENGTGKTTFIRMLAGNLEPD-EGSGQLPQLHISYKP-QKISP 560
L+ + G+F+ E++ ++G +G GK+T + +LAG E +G+ + L + +K+S
Sbjct: 98 LKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVSC 157
Query: 559 KSQGLVRSLLHDKIRDAYI-------------HPQFLTDVMKPMKIEEIMDQEVQNLSGG 419
L H +++A + + + +++ + + + +LSGG
Sbjct: 158 YIMQDDMLLPHLTVQEAMMVSAHLKLQEKDEGRREMVKEILTALGLLSCANTRTGSLSGG 217
Query: 418 ELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIK 299
+ +R+A+ L L V DEP++ LDS ++K
Sbjct: 218 QRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMK 257
>AF323661-1|AAK28839.1| 644|Homo sapiens ATP-binding cassette
transporter G1 variant II protein.
Length = 644
Score = 39.5 bits (88), Expect = 0.013
Identities = 36/160 (22%), Positives = 75/160 (46%), Gaps = 15/160 (9%)
Frame = -3
Query: 733 LRVMPGEFSDSEILVLLGENGTGKTTFIRMLAGNLEPD-EGSGQLPQLHISYKP-QKISP 560
L+ + G+F+ E++ ++G +G GK+T + +LAG E +G+ + L + +K+S
Sbjct: 79 LKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVSC 138
Query: 559 KSQGLVRSLLHDKIRDAYI-------------HPQFLTDVMKPMKIEEIMDQEVQNLSGG 419
L H +++A + + + +++ + + + +LSGG
Sbjct: 139 YIMQDDMLLPHLTVQEAMMVSAHLKLQEKDEGRREMVKEILTALGLLSCANTRTGSLSGG 198
Query: 418 ELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIK 299
+ +R+A+ L L V DEP++ LDS ++K
Sbjct: 199 QRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMK 238
>AF323660-1|AAK28838.1| 668|Homo sapiens ATP-binding cassette
transporter G1 variant I protein.
Length = 668
Score = 39.5 bits (88), Expect = 0.013
Identities = 36/160 (22%), Positives = 75/160 (46%), Gaps = 15/160 (9%)
Frame = -3
Query: 733 LRVMPGEFSDSEILVLLGENGTGKTTFIRMLAGNLEPD-EGSGQLPQLHISYKP-QKISP 560
L+ + G+F+ E++ ++G +G GK+T + +LAG E +G+ + L + +K+S
Sbjct: 103 LKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVSC 162
Query: 559 KSQGLVRSLLHDKIRDAYI-------------HPQFLTDVMKPMKIEEIMDQEVQNLSGG 419
L H +++A + + + +++ + + + +LSGG
Sbjct: 163 YIMQDDMLLPHLTVQEAMMVSAHLKLQEKDEGRREMVKEILTALGLLSCANTRTGSLSGG 222
Query: 418 ELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIK 299
+ +R+A+ L L V DEP++ LDS ++K
Sbjct: 223 QRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMK 262
>AF323658-5|AAK28834.1| 644|Homo sapiens ATP-binding cassette
transporter G1 variant II protein.
Length = 644
Score = 39.5 bits (88), Expect = 0.013
Identities = 36/160 (22%), Positives = 75/160 (46%), Gaps = 15/160 (9%)
Frame = -3
Query: 733 LRVMPGEFSDSEILVLLGENGTGKTTFIRMLAGNLEPD-EGSGQLPQLHISYKP-QKISP 560
L+ + G+F+ E++ ++G +G GK+T + +LAG E +G+ + L + +K+S
Sbjct: 79 LKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVSC 138
Query: 559 KSQGLVRSLLHDKIRDAYI-------------HPQFLTDVMKPMKIEEIMDQEVQNLSGG 419
L H +++A + + + +++ + + + +LSGG
Sbjct: 139 YIMQDDMLLPHLTVQEAMMVSAHLKLQEKDEGRREMVKEILTALGLLSCANTRTGSLSGG 198
Query: 418 ELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIK 299
+ +R+A+ L L V DEP++ LDS ++K
Sbjct: 199 QRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMK 238
>AF323658-4|AAK28836.1| 677|Homo sapiens ATP-binding cassette
transporter G1 variant V protein.
Length = 677
Score = 39.5 bits (88), Expect = 0.013
Identities = 36/160 (22%), Positives = 75/160 (46%), Gaps = 15/160 (9%)
Frame = -3
Query: 733 LRVMPGEFSDSEILVLLGENGTGKTTFIRMLAGNLEPD-EGSGQLPQLHISYKP-QKISP 560
L+ + G+F+ E++ ++G +G GK+T + +LAG E +G+ + L + +K+S
Sbjct: 112 LKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVSC 171
Query: 559 KSQGLVRSLLHDKIRDAYI-------------HPQFLTDVMKPMKIEEIMDQEVQNLSGG 419
L H +++A + + + +++ + + + +LSGG
Sbjct: 172 YIMQDDMLLPHLTVQEAMMVSAHLKLQEKDEGRREMVKEILTALGLLSCANTRTGSLSGG 231
Query: 418 ELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIK 299
+ +R+A+ L L V DEP++ LDS ++K
Sbjct: 232 QRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMK 271
>AF323658-3|AAK28837.1| 662|Homo sapiens ATP-binding cassette
transporter G1 variant IV protein.
Length = 662
Score = 39.5 bits (88), Expect = 0.013
Identities = 36/160 (22%), Positives = 75/160 (46%), Gaps = 15/160 (9%)
Frame = -3
Query: 733 LRVMPGEFSDSEILVLLGENGTGKTTFIRMLAGNLEPD-EGSGQLPQLHISYKP-QKISP 560
L+ + G+F+ E++ ++G +G GK+T + +LAG E +G+ + L + +K+S
Sbjct: 97 LKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVSC 156
Query: 559 KSQGLVRSLLHDKIRDAYI-------------HPQFLTDVMKPMKIEEIMDQEVQNLSGG 419
L H +++A + + + +++ + + + +LSGG
Sbjct: 157 YIMQDDMLLPHLTVQEAMMVSAHLKLQEKDEGRREMVKEILTALGLLSCANTRTGSLSGG 216
Query: 418 ELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIK 299
+ +R+A+ L L V DEP++ LDS ++K
Sbjct: 217 QRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMK 256
>AF323658-2|AAK28835.1| 663|Homo sapiens ATP-binding cassette
transporter G1 variant III protein.
Length = 663
Score = 39.5 bits (88), Expect = 0.013
Identities = 36/160 (22%), Positives = 75/160 (46%), Gaps = 15/160 (9%)
Frame = -3
Query: 733 LRVMPGEFSDSEILVLLGENGTGKTTFIRMLAGNLEPD-EGSGQLPQLHISYKP-QKISP 560
L+ + G+F+ E++ ++G +G GK+T + +LAG E +G+ + L + +K+S
Sbjct: 98 LKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVSC 157
Query: 559 KSQGLVRSLLHDKIRDAYI-------------HPQFLTDVMKPMKIEEIMDQEVQNLSGG 419
L H +++A + + + +++ + + + +LSGG
Sbjct: 158 YIMQDDMLLPHLTVQEAMMVSAHLKLQEKDEGRREMVKEILTALGLLSCANTRTGSLSGG 217
Query: 418 ELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIK 299
+ +R+A+ L L V DEP++ LDS ++K
Sbjct: 218 QRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMK 257
>AF323658-1|AAK28833.1| 668|Homo sapiens ATP-binding cassette
transporter G1 variant I protein.
Length = 668
Score = 39.5 bits (88), Expect = 0.013
Identities = 36/160 (22%), Positives = 75/160 (46%), Gaps = 15/160 (9%)
Frame = -3
Query: 733 LRVMPGEFSDSEILVLLGENGTGKTTFIRMLAGNLEPD-EGSGQLPQLHISYKP-QKISP 560
L+ + G+F+ E++ ++G +G GK+T + +LAG E +G+ + L + +K+S
Sbjct: 103 LKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVSC 162
Query: 559 KSQGLVRSLLHDKIRDAYI-------------HPQFLTDVMKPMKIEEIMDQEVQNLSGG 419
L H +++A + + + +++ + + + +LSGG
Sbjct: 163 YIMQDDMLLPHLTVQEAMMVSAHLKLQEKDEGRREMVKEILTALGLLSCANTRTGSLSGG 222
Query: 418 ELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIK 299
+ +R+A+ L L V DEP++ LDS ++K
Sbjct: 223 QRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMK 262
>AB038161-1|BAB13728.2| 674|Homo sapiens ABC transporter protein.
Length = 674
Score = 39.5 bits (88), Expect = 0.013
Identities = 36/160 (22%), Positives = 75/160 (46%), Gaps = 15/160 (9%)
Frame = -3
Query: 733 LRVMPGEFSDSEILVLLGENGTGKTTFIRMLAGNLEPD-EGSGQLPQLHISYKP-QKISP 560
L+ + G+F+ E++ ++G +G GK+T + +LAG E +G+ + L + +K+S
Sbjct: 97 LKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVSC 156
Query: 559 KSQGLVRSLLHDKIRDAYI-------------HPQFLTDVMKPMKIEEIMDQEVQNLSGG 419
L H +++A + + + +++ + + + +LSGG
Sbjct: 157 YIMQDDMLLPHLTVQEAMMVSAHLKLQEKDEGRREMVKEILTALGLLSCANTRTGSLSGG 216
Query: 418 ELQRVALVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIK 299
+ +R+A+ L L V DEP++ LDS ++K
Sbjct: 217 QRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMK 256
>BC141836-1|AAI41837.1| 693|Homo sapiens ABCB8 protein protein.
Length = 693
Score = 39.1 bits (87), Expect = 0.018
Identities = 27/92 (29%), Positives = 46/92 (50%)
Frame = -3
Query: 517 RDAYIHPQFLTDVMKPMKIEEIMDQEVQNLSGGELQRVALVLCLGKPADVYLIDEPSAYL 338
R+A H +F+T P ++ + LSGG+ QR+A+ L K V ++DE ++ L
Sbjct: 569 REANAH-EFITSF--PEGYNTVVGERGTTLSGGQKQRLAIARALIKQPTVLILDEATSAL 625
Query: 337 DSEQRLVAAKVIKRFILHAKRTGFVVEHDFIM 242
D+E V + + R A RT H+ ++
Sbjct: 626 DAESERVVQEALDR--ASAGRTVLAGTHEELL 655
>AL359846-6|CAH73579.1| 2261|Homo sapiens ATP-binding cassette,
sub-family A (ABC1), memberisiae) protein.
Length = 2261
Score = 39.1 bits (87), Expect = 0.018
Identities = 39/183 (21%), Positives = 79/183 (43%), Gaps = 16/183 (8%)
Frame = -3
Query: 712 FSDSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQL------PQLHISYKPQKISPKSQ 551
F + +I LG NG GKTT + +L G P G+ + ++ + + P+
Sbjct: 923 FYEGQITSFLGHNGAGKTTTMSILTGLFPPTSGTAYILGKDIRSEMSTIRQNLGVCPQHN 982
Query: 550 GLVRSLLHDKIRDAYIHPQFLTDVMKPMKIEEI----------MDQEVQNLSGGELQRVA 401
L L ++ Y + L++ ++E++ + + LSGG ++++
Sbjct: 983 VLFDMLTVEEHIWFYARLKGLSEKHVKAEMEQMALDVGLPSSKLKSKTSQLSGGMQRKLS 1042
Query: 400 LVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMATYLADR 221
+ L + V ++DEP+A +D R +++ ++ RT + H A L DR
Sbjct: 1043 VALAFVGGSKVVILDEPTAGVDPYSRRGIWELLLKY--RQGRTIILSTHHMDEADVLGDR 1100
Query: 220 VIV 212
+ +
Sbjct: 1101 IAI 1103
>AL353685-3|CAH72444.1| 2261|Homo sapiens ATP-binding cassette,
sub-family A (ABC1), memberog, Drosophila) protein.
Length = 2261
Score = 39.1 bits (87), Expect = 0.018
Identities = 39/183 (21%), Positives = 79/183 (43%), Gaps = 16/183 (8%)
Frame = -3
Query: 712 FSDSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQL------PQLHISYKPQKISPKSQ 551
F + +I LG NG GKTT + +L G P G+ + ++ + + P+
Sbjct: 923 FYEGQITSFLGHNGAGKTTTMSILTGLFPPTSGTAYILGKDIRSEMSTIRQNLGVCPQHN 982
Query: 550 GLVRSLLHDKIRDAYIHPQFLTDVMKPMKIEEI----------MDQEVQNLSGGELQRVA 401
L L ++ Y + L++ ++E++ + + LSGG ++++
Sbjct: 983 VLFDMLTVEEHIWFYARLKGLSEKHVKAEMEQMALDVGLPSSKLKSKTSQLSGGMQRKLS 1042
Query: 400 LVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMATYLADR 221
+ L + V ++DEP+A +D R +++ ++ RT + H A L DR
Sbjct: 1043 VALAFVGGSKVVILDEPTAGVDPYSRRGIWELLLKY--RQGRTIILSTHHMDEADVLGDR 1100
Query: 220 VIV 212
+ +
Sbjct: 1101 IAI 1103
>AK130814-1|BAC85435.1| 546|Homo sapiens protein ( Homo sapiens
cDNA FLJ27304 fis, clone TMS05176, highly similar to
ATP-binding cassette, sub-family A, member 1. ).
Length = 546
Score = 39.1 bits (87), Expect = 0.018
Identities = 39/183 (21%), Positives = 79/183 (43%), Gaps = 16/183 (8%)
Frame = -3
Query: 712 FSDSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQL------PQLHISYKPQKISPKSQ 551
F + +I LG NG GKTT + +L G P G+ + ++ + + P+
Sbjct: 97 FYEGQITSFLGHNGAGKTTTMSILTGLFPPTSGTAYILGKDIRSEMSTIRQNLGVCPQHN 156
Query: 550 GLVRSLLHDKIRDAYIHPQFLTDVMKPMKIEEI----------MDQEVQNLSGGELQRVA 401
L L ++ Y + L++ ++E++ + + LSGG ++++
Sbjct: 157 VLFDMLTVEEHIWFYARLKGLSEKHVKAEMEQMALDVGLPSSKLKSKTSQLSGGMQRKLS 216
Query: 400 LVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMATYLADR 221
+ L + V ++DEP+A +D R +++ ++ RT + H A L DR
Sbjct: 217 VALAFVGGSKVVILDEPTAGVDPYSRRGIWELLLKY--RQGRTIILSTHHMDEADVLGDR 274
Query: 220 VIV 212
+ +
Sbjct: 275 IAI 277
>AK091270-1|BAC03623.1| 293|Homo sapiens protein ( Homo sapiens
cDNA FLJ33951 fis, clone CTONG2018483, weakly similar to
ATP-BINDING CASSETTE, SUB-FAMILY A, MEMBER 1. ).
Length = 293
Score = 39.1 bits (87), Expect = 0.018
Identities = 20/56 (35%), Positives = 35/56 (62%), Gaps = 1/56 (1%)
Frame = -3
Query: 499 PQFLTDVMKPMKIEEIMDQEVQNLSGGELQRVALVLCL-GKPADVYLIDEPSAYLD 335
P+ D+++ + +E D+ V SGG ++++ L L GKP D+ L+DEPS+ +D
Sbjct: 69 PEVAGDLIRRLHLEAHADKPVATYSGGTKRKLSTALALVGKP-DILLLDEPSSGMD 123
>AJ012376-1|CAA10005.1| 2201|Homo sapiens ATP-binding cassette
transporter-1 (ABC-1) protein.
Length = 2201
Score = 39.1 bits (87), Expect = 0.018
Identities = 39/183 (21%), Positives = 79/183 (43%), Gaps = 16/183 (8%)
Frame = -3
Query: 712 FSDSEILVLLGENGTGKTTFIRMLAGNLEPDEGSGQL------PQLHISYKPQKISPKSQ 551
F + +I LG NG GKTT + +L G P G+ + ++ + + P+
Sbjct: 863 FYEGQITSFLGHNGAGKTTTMSILTGLFPPTSGTAYILGKDIRSEMSTIRQNLGVCPQHN 922
Query: 550 GLVRSLLHDKIRDAYIHPQFLTDVMKPMKIEEI----------MDQEVQNLSGGELQRVA 401
L L ++ Y + L++ ++E++ + + LSGG ++++
Sbjct: 923 VLFDMLTVEEHIWFYARLKGLSEKHVKAEMEQMALDVGLPSSKLKSKTSQLSGGMQRKLS 982
Query: 400 LVLCLGKPADVYLIDEPSAYLDSEQRLVAAKVIKRFILHAKRTGFVVEHDFIMATYLADR 221
+ L + V ++DEP+A +D R +++ ++ RT + H A L DR
Sbjct: 983 VALAFVGGSKVVILDEPTAGVDPYSRRGIWELLLKY--RQGRTIILSTHHMDEADVLGDR 1040
Query: 220 VIV 212
+ +
Sbjct: 1041 IAI 1043
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 116,632,463
Number of Sequences: 237096
Number of extensions: 2576633
Number of successful extensions: 7037
Number of sequences better than 10.0: 393
Number of HSP's better than 10.0 without gapping: 6366
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6977
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 9590293096
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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