Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P09_pT_K22
(778 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
J05262-1|AAA52423.1| 353|Homo sapiens FDPS protein. 174 3e-43
M29863-1|AAA35820.1| 346|Homo sapiens protein ( Human farnesyl ... 173 6e-43
D14697-1|BAA03523.2| 420|Homo sapiens KIAA1293 protein. 173 6e-43
BC010004-1|AAH10004.1| 419|Homo sapiens farnesyl diphosphate sy... 173 6e-43
AL139410-1|CAI12715.1| 419|Homo sapiens farnesyl diphosphate sy... 173 6e-43
Z47055-1|CAA87327.1| 348|Homo sapiens farnesyl pyrophosphate sy... 155 1e-37
BC050292-1|AAH50292.1| 298|Homo sapiens LOC619190 protein protein. 142 1e-33
M87434-1|AAA60607.1| 727|Homo sapiens 71 kDa 2'5' oligoadenylat... 30 8.1
M87284-1|AAA60606.1| 687|Homo sapiens 2'5' oligoadenylate synth... 30 8.1
BC049215-1|AAH49215.1| 687|Homo sapiens 2'-5'-oligoadenylate sy... 30 8.1
>J05262-1|AAA52423.1| 353|Homo sapiens FDPS protein.
Length = 353
Score = 174 bits (423), Expect = 3e-43
Identities = 91/242 (37%), Positives = 131/242 (54%), Gaps = 1/242 (0%)
Frame = -1
Query: 775 RRGMPCWYRXPEVGITCAFNDSLLIHSSLFEFXKTNFRTNPNYMKMFELFNETLWRTSMG 596
RRG CWY+ P VG+ A ND+ L+ + ++ K R P Y+ + ELF ++ ++T +G
Sbjct: 112 RRGQTCWYQKPGVGLD-AINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIG 170
Query: 595 QHLDHVTGNR-KTDYSSFTLDRXXXXXXXXXXXXXYNLPVSLGLLLAENVDEKIYKSAQD 419
Q LD +T + D FT R + LP++ + +A EK + +A+
Sbjct: 171 QTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKK 230
Query: 418 ICLEIGTMFQIQDDFIDCFGDEIKTGKVGTDIQERKCTWLAVQALQRCTEAQRTVFKACY 239
I LE+G FQIQDD++D FGD TGK+GTDIQ+ KC+WL VQ LQR T Q + K Y
Sbjct: 231 ILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENY 290
Query: 238 GSSEPAHVERIKRLYEDLHLPQIYKHQEKAMYDNIIRQIENIPIEAARVLFKKLLDITYN 59
G E V R+K LYE+L LP ++ E+ Y +I+ IE +F L Y
Sbjct: 291 GQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYK 350
Query: 58 RQ 53
R+
Sbjct: 351 RR 352
>M29863-1|AAA35820.1| 346|Homo sapiens protein ( Human farnesyl
pyrophosphate synthetase mRNA (hpt807), 3' end. ).
Length = 346
Score = 173 bits (421), Expect = 6e-43
Identities = 91/242 (37%), Positives = 131/242 (54%), Gaps = 1/242 (0%)
Frame = -1
Query: 775 RRGMPCWYRXPEVGITCAFNDSLLIHSSLFEFXKTNFRTNPNYMKMFELFNETLWRTSMG 596
RRG CWY+ P VG+ A ND+ L+ + ++ K R P Y+ + ELF ++ ++T +G
Sbjct: 105 RRGQICWYQKPGVGLD-AINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIG 163
Query: 595 QHLDHVTGNR-KTDYSSFTLDRXXXXXXXXXXXXXYNLPVSLGLLLAENVDEKIYKSAQD 419
Q LD +T + D FT R + LP++ + +A EK + +A+
Sbjct: 164 QTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKK 223
Query: 418 ICLEIGTMFQIQDDFIDCFGDEIKTGKVGTDIQERKCTWLAVQALQRCTEAQRTVFKACY 239
I LE+G FQIQDD++D FGD TGK+GTDIQ+ KC+WL VQ LQR T Q + K Y
Sbjct: 224 ILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENY 283
Query: 238 GSSEPAHVERIKRLYEDLHLPQIYKHQEKAMYDNIIRQIENIPIEAARVLFKKLLDITYN 59
G E V R+K LYE+L LP ++ E+ Y +I+ IE +F L Y
Sbjct: 284 GQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYK 343
Query: 58 RQ 53
R+
Sbjct: 344 RR 345
>D14697-1|BAA03523.2| 420|Homo sapiens KIAA1293 protein.
Length = 420
Score = 173 bits (421), Expect = 6e-43
Identities = 91/242 (37%), Positives = 131/242 (54%), Gaps = 1/242 (0%)
Frame = -1
Query: 775 RRGMPCWYRXPEVGITCAFNDSLLIHSSLFEFXKTNFRTNPNYMKMFELFNETLWRTSMG 596
RRG CWY+ P VG+ A ND+ L+ + ++ K R P Y+ + ELF ++ ++T +G
Sbjct: 179 RRGQICWYQKPGVGLD-AINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIG 237
Query: 595 QHLDHVTGNR-KTDYSSFTLDRXXXXXXXXXXXXXYNLPVSLGLLLAENVDEKIYKSAQD 419
Q LD +T + D FT R + LP++ + +A EK + +A+
Sbjct: 238 QTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKK 297
Query: 418 ICLEIGTMFQIQDDFIDCFGDEIKTGKVGTDIQERKCTWLAVQALQRCTEAQRTVFKACY 239
I LE+G FQIQDD++D FGD TGK+GTDIQ+ KC+WL VQ LQR T Q + K Y
Sbjct: 298 ILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENY 357
Query: 238 GSSEPAHVERIKRLYEDLHLPQIYKHQEKAMYDNIIRQIENIPIEAARVLFKKLLDITYN 59
G E V R+K LYE+L LP ++ E+ Y +I+ IE +F L Y
Sbjct: 358 GQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYK 417
Query: 58 RQ 53
R+
Sbjct: 418 RR 419
>BC010004-1|AAH10004.1| 419|Homo sapiens farnesyl diphosphate
synthase (farnesyl pyrophosphate synthetase,
dimethylallyl protein.
Length = 419
Score = 173 bits (421), Expect = 6e-43
Identities = 91/242 (37%), Positives = 131/242 (54%), Gaps = 1/242 (0%)
Frame = -1
Query: 775 RRGMPCWYRXPEVGITCAFNDSLLIHSSLFEFXKTNFRTNPNYMKMFELFNETLWRTSMG 596
RRG CWY+ P VG+ A ND+ L+ + ++ K R P Y+ + ELF ++ ++T +G
Sbjct: 178 RRGQICWYQKPGVGLD-AINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIG 236
Query: 595 QHLDHVTGNR-KTDYSSFTLDRXXXXXXXXXXXXXYNLPVSLGLLLAENVDEKIYKSAQD 419
Q LD +T + D FT R + LP++ + +A EK + +A+
Sbjct: 237 QTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKK 296
Query: 418 ICLEIGTMFQIQDDFIDCFGDEIKTGKVGTDIQERKCTWLAVQALQRCTEAQRTVFKACY 239
I LE+G FQIQDD++D FGD TGK+GTDIQ+ KC+WL VQ LQR T Q + K Y
Sbjct: 297 ILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENY 356
Query: 238 GSSEPAHVERIKRLYEDLHLPQIYKHQEKAMYDNIIRQIENIPIEAARVLFKKLLDITYN 59
G E V R+K LYE+L LP ++ E+ Y +I+ IE +F L Y
Sbjct: 357 GQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYK 416
Query: 58 RQ 53
R+
Sbjct: 417 RR 418
>AL139410-1|CAI12715.1| 419|Homo sapiens farnesyl diphosphate
synthase (farnesyl pyrophosphate synthetase,
dimethylallyl protein.
Length = 419
Score = 173 bits (421), Expect = 6e-43
Identities = 91/242 (37%), Positives = 131/242 (54%), Gaps = 1/242 (0%)
Frame = -1
Query: 775 RRGMPCWYRXPEVGITCAFNDSLLIHSSLFEFXKTNFRTNPNYMKMFELFNETLWRTSMG 596
RRG CWY+ P VG+ A ND+ L+ + ++ K R P Y+ + ELF ++ ++T +G
Sbjct: 178 RRGQICWYQKPGVGLD-AINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIG 236
Query: 595 QHLDHVTGNR-KTDYSSFTLDRXXXXXXXXXXXXXYNLPVSLGLLLAENVDEKIYKSAQD 419
Q LD +T + D FT R + LP++ + +A EK + +A+
Sbjct: 237 QTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKK 296
Query: 418 ICLEIGTMFQIQDDFIDCFGDEIKTGKVGTDIQERKCTWLAVQALQRCTEAQRTVFKACY 239
I LE+G FQIQDD++D FGD TGK+GTDIQ+ KC+WL VQ LQR T Q + K Y
Sbjct: 297 ILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENY 356
Query: 238 GSSEPAHVERIKRLYEDLHLPQIYKHQEKAMYDNIIRQIENIPIEAARVLFKKLLDITYN 59
G E V R+K LYE+L LP ++ E+ Y +I+ IE +F L Y
Sbjct: 357 GQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYK 416
Query: 58 RQ 53
R+
Sbjct: 417 RR 418
>Z47055-1|CAA87327.1| 348|Homo sapiens farnesyl pyrophosphate
synthetase like-4 protein.
Length = 348
Score = 155 bits (377), Expect = 1e-37
Identities = 86/241 (35%), Positives = 122/241 (50%), Gaps = 1/241 (0%)
Frame = -1
Query: 775 RRGMPCWYRXPEVGITCAFNDSLLIHSSLFEFXKTNFRTNPNYMKMFELFNETLWRTSMG 596
RRG CWY+ P VG+ A +D+ L+ + ++ K R P Y+ + ELF ++ ++T +G
Sbjct: 107 RRGQICWYQKPGVGLD-AIDDANLLEACIYPLLKLYCREQPYYLNLIELFLQSSYQTEIG 165
Query: 595 QHLDHVTGNR-KTDYSSFTLDRXXXXXXXXXXXXXYNLPVSLGLLLAENVDEKIYKSAQD 419
Q LD +T + D FT R LP++ V EK + +A
Sbjct: 166 QTLDLLTXPQGNVDLVRFTEKRYISIVKYKTALSSSYLPIAAAXXXXGIVXEKEHANAXK 225
Query: 418 ICLEIGTMFQIQDDFIDCFGDEIKTGKVGTDIQERKCTWLAVQALQRCTEAQRTVFKACY 239
I LE+G QIQDD+++ FGD TGK+GTDIQ+ KC L VQ L R T Q + K Y
Sbjct: 226 ILLEMGEFSQIQDDYLELFGDPSVTGKIGTDIQDXKCNCLXVQCLXRATPEQYQILKENY 285
Query: 238 GSSEPAHVERIKRLYEDLHLPQIYKHQEKAMYDNIIRQIENIPIEAARVLFKKLLDITYN 59
G E V R+K LYE+L LP ++ E+ Y +I+ IE +F L Y
Sbjct: 286 GQKEAEKVPRVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARQIYK 345
Query: 58 R 56
R
Sbjct: 346 R 346
>BC050292-1|AAH50292.1| 298|Homo sapiens LOC619190 protein protein.
Length = 298
Score = 142 bits (345), Expect = 1e-33
Identities = 76/219 (34%), Positives = 116/219 (52%), Gaps = 1/219 (0%)
Frame = -1
Query: 772 RGMPCWYRXPEVGITCAFNDSLLIHSSLFEFXKTNFRTNPNYMKMFELFNETLWRTSMGQ 593
+G WY+ +G+ A ND++L+ + ++ K R P Y+ + ELF + ++T +GQ
Sbjct: 81 QGQISWYQKLGMGLD-AINDAILLEACIYCLLKLYCREQPYYLNLMELFQQNSYQTEIGQ 139
Query: 592 HLDHVTGNR-KTDYSSFTLDRXXXXXXXXXXXXXYNLPVSLGLLLAENVDEKIYKSAQDI 416
LD +T + D T R + LPV+ + ++ D+K + SA+ I
Sbjct: 140 TLDLITTPQGNVDLRRCTEKRHKSVVKYKTAFYSFYLPVAAAMYMSRMDDKKEHTSAKKI 199
Query: 415 CLEIGTMFQIQDDFIDCFGDEIKTGKVGTDIQERKCTWLAVQALQRCTEAQRTVFKACYG 236
LEI FQIQDD++D GD TG+VG D Q+ KC+WL VQ L + T Q + K Y
Sbjct: 200 LLEIQEFFQIQDDYLDFSGDPSVTGRVGNDFQDNKCSWLVVQCLLQATPEQYQILKENYR 259
Query: 235 SSEPAHVERIKRLYEDLHLPQIYKHQEKAMYDNIIRQIE 119
E V R+K LYE+L LP ++ EK Y +++ IE
Sbjct: 260 QKEAEKVARVKALYEELDLPAVFLQYEKDSYSHVMGLIE 298
>M87434-1|AAA60607.1| 727|Homo sapiens 71 kDa 2'5' oligoadenylate
synthetase protein.
Length = 727
Score = 30.3 bits (65), Expect = 8.1
Identities = 12/31 (38%), Positives = 20/31 (64%)
Frame = -2
Query: 336 LVQIYKSANVLGWQFKRCSAVLKHNVQYSKP 244
L+ +YKS+++ G +F C VL+ N S+P
Sbjct: 506 LIDLYKSSDLPGGEFSTCFTVLQRNFIRSRP 536
>M87284-1|AAA60606.1| 687|Homo sapiens 2'5' oligoadenylate
synthetase protein.
Length = 687
Score = 30.3 bits (65), Expect = 8.1
Identities = 12/31 (38%), Positives = 20/31 (64%)
Frame = -2
Query: 336 LVQIYKSANVLGWQFKRCSAVLKHNVQYSKP 244
L+ +YKS+++ G +F C VL+ N S+P
Sbjct: 506 LIDLYKSSDLPGGEFSTCFTVLQRNFIRSRP 536
>BC049215-1|AAH49215.1| 687|Homo sapiens 2'-5'-oligoadenylate
synthetase 2, 69/71kDa protein.
Length = 687
Score = 30.3 bits (65), Expect = 8.1
Identities = 12/31 (38%), Positives = 20/31 (64%)
Frame = -2
Query: 336 LVQIYKSANVLGWQFKRCSAVLKHNVQYSKP 244
L+ +YKS+++ G +F C VL+ N S+P
Sbjct: 506 LIDLYKSSDLPGGEFSTCFTVLQRNFIRSRP 536
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 110,275,545
Number of Sequences: 237096
Number of extensions: 2193688
Number of successful extensions: 4042
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3932
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4029
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 9423020542
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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