Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P09_pT_J22
(682 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X54938-1|CAA38700.1| 461|Homo sapiens inositol 1,4,5-triphospha... 172 1e-42
BC026331-1|AAH26331.1| 461|Homo sapiens inositol 1,4,5-trisphos... 172 1e-42
Y18024-1|CAB65055.3| 946|Homo sapiens inositol 1,4,5-trisphosph... 149 7e-36
X57206-1|CAA40491.1| 472|Homo sapiens 1D-myo-inositol-trisphosp... 149 7e-36
D38169-1|BAA22524.1| 604|Homo sapiens inositol 1,4,5-trisphosph... 149 7e-36
BC060788-1|AAH60788.1| 683|Homo sapiens inositol 1,4,5-trisphos... 149 7e-36
AY513281-1|AAT08034.1| 472|Homo sapiens proliferation-inducing ... 149 7e-36
AL365444-3|CAH70188.1| 946|Homo sapiens inositol 1,4,5-trisphos... 149 7e-36
AJ290975-1|CAC40815.1| 683|Homo sapiens inositol 1,4,5-trisphos... 149 7e-36
AJ242780-1|CAC40650.1| 946|Homo sapiens inositol 1,4,5-trisphos... 149 7e-36
Y11999-1|CAA72728.1| 137|Homo sapiens inositol 1,4,5-trisphosph... 110 4e-24
BC033516-1|AAH33516.1| 336|Homo sapiens TBC1 domain family, mem... 35 0.23
AY143550-1|AAN38838.1| 1406|Homo sapiens ubiquitin-specific prot... 31 2.9
X63547-2|CAA45111.1| 1089|Homo sapiens oncogene protein. 30 8.8
X63546-2|CAA45109.1| 586|Homo sapiens oncogene protein. 30 8.8
>X54938-1|CAA38700.1| 461|Homo sapiens inositol 1,4,5-triphosphate
3-kinase protein.
Length = 461
Score = 172 bits (418), Expect = 1e-42
Identities = 80/166 (48%), Positives = 105/166 (63%), Gaps = 1/166 (0%)
Frame = -3
Query: 680 DLYEKMVRXDPNAPTESEHAARAVXKLRYMQFREQRSSSAEQGFRIEAVKLPGEPALTDL 501
D+Y+KM+ DP APTE EHA RAV K RYMQ+RE SSS GFRIE +K TD
Sbjct: 287 DMYKKMLAVDPEAPTEEEHAQRAVTKPRYMQWREGISSSTTLGFRIEGIKKADGSCSTDF 346
Query: 500 QKIREPHQLAATVARFLGNDERARREIASRLREIRDHFERSDFFKSHEIVGSSIFIIYDD 321
+ R Q+ F+ DE R +RL++IRD E S+FF+ HE++GSS+ ++D
Sbjct: 347 KTTRSREQVLRVFEEFVQGDEEVLRRYLNRLQQIRDTLEVSEFFRRHEVIGSSLLFVHDH 406
Query: 320 -ERVGAWLIDFAKTRKIPTGSQVNHRAPWQQGNHEEGFLFGLDRLI 186
R G WLIDF KT +P G ++HR PW++GN E+G+L GLD LI
Sbjct: 407 CHRAGVWLIDFGKTTPLPDGQILDHRRPWEEGNREDGYLLGLDNLI 452
>BC026331-1|AAH26331.1| 461|Homo sapiens inositol
1,4,5-trisphosphate 3-kinase A protein.
Length = 461
Score = 172 bits (418), Expect = 1e-42
Identities = 80/166 (48%), Positives = 105/166 (63%), Gaps = 1/166 (0%)
Frame = -3
Query: 680 DLYEKMVRXDPNAPTESEHAARAVXKLRYMQFREQRSSSAEQGFRIEAVKLPGEPALTDL 501
D+Y+KM+ DP APTE EHA RAV K RYMQ+RE SSS GFRIE +K TD
Sbjct: 287 DMYKKMLAVDPEAPTEEEHAQRAVTKPRYMQWREGISSSTTLGFRIEGIKKADGSCSTDF 346
Query: 500 QKIREPHQLAATVARFLGNDERARREIASRLREIRDHFERSDFFKSHEIVGSSIFIIYDD 321
+ R Q+ F+ DE R +RL++IRD E S+FF+ HE++GSS+ ++D
Sbjct: 347 KTTRSREQVLRVFEEFVQGDEEVLRRYLNRLQQIRDTLEVSEFFRRHEVIGSSLLFVHDH 406
Query: 320 -ERVGAWLIDFAKTRKIPTGSQVNHRAPWQQGNHEEGFLFGLDRLI 186
R G WLIDF KT +P G ++HR PW++GN E+G+L GLD LI
Sbjct: 407 CHRAGVWLIDFGKTTPLPDGQILDHRRPWEEGNREDGYLLGLDNLI 452
>Y18024-1|CAB65055.3| 946|Homo sapiens inositol 1,4,5-trisphosphate
3-kinase B protein.
Length = 946
Score = 149 bits (362), Expect = 7e-36
Identities = 72/169 (42%), Positives = 97/169 (57%), Gaps = 1/169 (0%)
Frame = -3
Query: 680 DLYEKMVRXDPNAPTESEHAARAVXKLRYMQFREQRSSSAEQGFRIEAVKLPGEPALTDL 501
D+Y+KM+ DP APTE E A RAV K RYMQ+RE SS+A GFRIE +K D
Sbjct: 768 DMYQKMIEVDPEAPTEEEKAQRAVTKPRYMQWRETISSTATLGFRIEGIKKEDGTVNRDF 827
Query: 500 QKIREPHQLAATVARFLGNDERARREIASRLREIRDHFERSDFFKSHEIVGSSIFIIYD- 324
+K + Q+ F + RL+ IR E S FFK HE++GSS+ I+D
Sbjct: 828 KKTKTREQVTEAFREFTKGNHNILIAYRDRLKAIRTTLEVSPFFKCHEVIGSSLLFIHDK 887
Query: 323 DERVGAWLIDFAKTRKIPTGSQVNHRAPWQQGNHEEGFLFGLDRLIQTI 177
E+ W+IDF KT +P G + H PWQ+GN E+G+L GL+ L+ +
Sbjct: 888 KEQAKVWMIDFGKTTPLPEGQTLQHDVPWQEGNREDGYLSGLNNLVDIL 936
>X57206-1|CAA40491.1| 472|Homo sapiens
1D-myo-inositol-trisphosphate 3-kinase protein.
Length = 472
Score = 149 bits (362), Expect = 7e-36
Identities = 72/169 (42%), Positives = 97/169 (57%), Gaps = 1/169 (0%)
Frame = -3
Query: 680 DLYEKMVRXDPNAPTESEHAARAVXKLRYMQFREQRSSSAEQGFRIEAVKLPGEPALTDL 501
D+Y+KM+ DP APTE E A RAV K RYMQ+RE SS+A GFRIE +K D
Sbjct: 294 DMYQKMIEVDPEAPTEEEKAQRAVTKPRYMQWRETISSTATLGFRIEGIKKEDGTVNRDF 353
Query: 500 QKIREPHQLAATVARFLGNDERARREIASRLREIRDHFERSDFFKSHEIVGSSIFIIYD- 324
+K + Q+ F + RL+ IR E S FFK HE++GSS+ I+D
Sbjct: 354 KKTKTREQVTEAFREFTKGNHNILIAYRDRLKAIRTTLEVSPFFKCHEVIGSSLLFIHDK 413
Query: 323 DERVGAWLIDFAKTRKIPTGSQVNHRAPWQQGNHEEGFLFGLDRLIQTI 177
E+ W+IDF KT +P G + H PWQ+GN E+G+L GL+ L+ +
Sbjct: 414 KEQAKVWMIDFGKTTPLPEGQTLQHDVPWQEGNREDGYLSGLNNLVDIL 462
>D38169-1|BAA22524.1| 604|Homo sapiens inositol 1,4,5-trisphosphate
3-kinase isoenzyme protein.
Length = 604
Score = 149 bits (362), Expect = 7e-36
Identities = 71/166 (42%), Positives = 102/166 (61%), Gaps = 1/166 (0%)
Frame = -3
Query: 680 DLYEKMVRXDPNAPTESEHAARAVXKLRYMQFREQRSSSAEQGFRIEAVKLPGEPALTDL 501
D+YEKMV DP APT EHA AV K RYMQ+RE SS++ GFRIE +K T+
Sbjct: 430 DMYEKMVAVDPGAPTPEEHAQGAVTKPRYMQWRETMSSTSTLGFRIEGIKKADGTCNTNF 489
Query: 500 QKIREPHQLAATVARFLGNDERARREIASRLREIRDHFERSDFFKSHEIVGSSIFIIYDD 321
+K + Q+ + F+ D ++ + L E+R+ E S FFK+HE+VGSS+ ++D
Sbjct: 490 KKTQALEQVTKVLEDFVDGDHVILQKYVACLEELREALEISPFFKTHEVVGSSLLFVHDH 549
Query: 320 ERVG-AWLIDFAKTRKIPTGSQVNHRAPWQQGNHEEGFLFGLDRLI 186
+ W+IDF KT +P ++HR PW +GN E+G+L+GLD +I
Sbjct: 550 TGLAKVWMIDFGKTVALPDHQTLSHRLPWAEGNREDGYLWGLDNMI 595
>BC060788-1|AAH60788.1| 683|Homo sapiens inositol 1,4,5-trisphosphate
3-kinase C protein.
Length = 683
Score = 149 bits (362), Expect = 7e-36
Identities = 71/166 (42%), Positives = 102/166 (61%), Gaps = 1/166 (0%)
Frame = -3
Query: 680 DLYEKMVRXDPNAPTESEHAARAVXKLRYMQFREQRSSSAEQGFRIEAVKLPGEPALTDL 501
D+YEKMV DP APT EHA AV K RYMQ+RE SS++ GFRIE +K T+
Sbjct: 509 DMYEKMVAVDPGAPTPEEHAQGAVTKPRYMQWRETMSSTSTLGFRIEGIKKADGTCNTNF 568
Query: 500 QKIREPHQLAATVARFLGNDERARREIASRLREIRDHFERSDFFKSHEIVGSSIFIIYDD 321
+K + Q+ + F+ D ++ + L E+R+ E S FFK+HE+VGSS+ ++D
Sbjct: 569 KKTQALEQVTKVLEDFVDGDHVILQKYVACLEELREALEISPFFKTHEVVGSSLLFVHDH 628
Query: 320 ERVG-AWLIDFAKTRKIPTGSQVNHRAPWQQGNHEEGFLFGLDRLI 186
+ W+IDF KT +P ++HR PW +GN E+G+L+GLD +I
Sbjct: 629 TGLAKVWMIDFGKTVALPDHQTLSHRLPWAEGNREDGYLWGLDNMI 674
>AY513281-1|AAT08034.1| 472|Homo sapiens proliferation-inducing
protein 37 protein.
Length = 472
Score = 149 bits (362), Expect = 7e-36
Identities = 72/169 (42%), Positives = 97/169 (57%), Gaps = 1/169 (0%)
Frame = -3
Query: 680 DLYEKMVRXDPNAPTESEHAARAVXKLRYMQFREQRSSSAEQGFRIEAVKLPGEPALTDL 501
D+Y+KM+ DP APTE E A RAV K RYMQ+RE SS+A GFRIE +K D
Sbjct: 294 DMYQKMIEVDPEAPTEEEKAQRAVTKPRYMQWRETISSTATLGFRIEGIKKEDGTVNRDF 353
Query: 500 QKIREPHQLAATVARFLGNDERARREIASRLREIRDHFERSDFFKSHEIVGSSIFIIYD- 324
+K + Q+ F + RL+ IR E S FFK HE++GSS+ I+D
Sbjct: 354 KKTKTREQVTEAFREFTKGNHNILIAYRDRLKAIRTTLEVSPFFKCHEVIGSSLLFIHDK 413
Query: 323 DERVGAWLIDFAKTRKIPTGSQVNHRAPWQQGNHEEGFLFGLDRLIQTI 177
E+ W+IDF KT +P G + H PWQ+GN E+G+L GL+ L+ +
Sbjct: 414 KEQAKVWMIDFGKTTPLPEGQTLQHDVPWQEGNREDGYLSGLNNLVDIL 462
>AL365444-3|CAH70188.1| 946|Homo sapiens inositol 1,4,5-trisphosphate
3-kinase B protein.
Length = 946
Score = 149 bits (362), Expect = 7e-36
Identities = 72/169 (42%), Positives = 97/169 (57%), Gaps = 1/169 (0%)
Frame = -3
Query: 680 DLYEKMVRXDPNAPTESEHAARAVXKLRYMQFREQRSSSAEQGFRIEAVKLPGEPALTDL 501
D+Y+KM+ DP APTE E A RAV K RYMQ+RE SS+A GFRIE +K D
Sbjct: 768 DMYQKMIEVDPEAPTEEEKAQRAVTKPRYMQWRETISSTATLGFRIEGIKKEDGTVNRDF 827
Query: 500 QKIREPHQLAATVARFLGNDERARREIASRLREIRDHFERSDFFKSHEIVGSSIFIIYD- 324
+K + Q+ F + RL+ IR E S FFK HE++GSS+ I+D
Sbjct: 828 KKTKTREQVTEAFREFTKGNHNILIAYRDRLKAIRTTLEVSPFFKCHEVIGSSLLFIHDK 887
Query: 323 DERVGAWLIDFAKTRKIPTGSQVNHRAPWQQGNHEEGFLFGLDRLIQTI 177
E+ W+IDF KT +P G + H PWQ+GN E+G+L GL+ L+ +
Sbjct: 888 KEQAKVWMIDFGKTTPLPEGQTLQHDVPWQEGNREDGYLSGLNNLVDIL 936
>AJ290975-1|CAC40815.1| 683|Homo sapiens inositol 1,4,5-trisphosphate
3-kinase C protein.
Length = 683
Score = 149 bits (362), Expect = 7e-36
Identities = 71/166 (42%), Positives = 102/166 (61%), Gaps = 1/166 (0%)
Frame = -3
Query: 680 DLYEKMVRXDPNAPTESEHAARAVXKLRYMQFREQRSSSAEQGFRIEAVKLPGEPALTDL 501
D+YEKMV DP APT EHA AV K RYMQ+RE SS++ GFRIE +K T+
Sbjct: 509 DMYEKMVAVDPGAPTPEEHAQGAVTKPRYMQWRETMSSTSTLGFRIEGIKKADGTCNTNF 568
Query: 500 QKIREPHQLAATVARFLGNDERARREIASRLREIRDHFERSDFFKSHEIVGSSIFIIYDD 321
+K + Q+ + F+ D ++ + L E+R+ E S FFK+HE+VGSS+ ++D
Sbjct: 569 KKTQALEQVTKVLEDFVDGDHVILQKYVACLEELREALEISPFFKTHEVVGSSLLFVHDH 628
Query: 320 ERVG-AWLIDFAKTRKIPTGSQVNHRAPWQQGNHEEGFLFGLDRLI 186
+ W+IDF KT +P ++HR PW +GN E+G+L+GLD +I
Sbjct: 629 TGLAKVWMIDFGKTVALPDHQTLSHRLPWAEGNREDGYLWGLDNMI 674
>AJ242780-1|CAC40650.1| 946|Homo sapiens inositol 1,4,5-trisphosphate
3-kinase, isoform B protein.
Length = 946
Score = 149 bits (362), Expect = 7e-36
Identities = 72/169 (42%), Positives = 97/169 (57%), Gaps = 1/169 (0%)
Frame = -3
Query: 680 DLYEKMVRXDPNAPTESEHAARAVXKLRYMQFREQRSSSAEQGFRIEAVKLPGEPALTDL 501
D+Y+KM+ DP APTE E A RAV K RYMQ+RE SS+A GFRIE +K D
Sbjct: 768 DMYQKMIEVDPEAPTEEEKAQRAVTKPRYMQWRETISSTATLGFRIEGIKKEDGTVNRDF 827
Query: 500 QKIREPHQLAATVARFLGNDERARREIASRLREIRDHFERSDFFKSHEIVGSSIFIIYD- 324
+K + Q+ F + RL+ IR E S FFK HE++GSS+ I+D
Sbjct: 828 KKTKTREQVTEAFREFTKGNHNILIAYRDRLKAIRTTLEVSPFFKCHEVIGSSLLFIHDK 887
Query: 323 DERVGAWLIDFAKTRKIPTGSQVNHRAPWQQGNHEEGFLFGLDRLIQTI 177
E+ W+IDF KT +P G + H PWQ+GN E+G+L GL+ L+ +
Sbjct: 888 KEQAKVWMIDFGKTTPLPEGQTLQHDVPWQEGNREDGYLSGLNNLVDIL 936
>Y11999-1|CAA72728.1| 137|Homo sapiens inositol 1,4,5-trisphosphate
3-kinase protein.
Length = 137
Score = 110 bits (265), Expect = 4e-24
Identities = 53/137 (38%), Positives = 81/137 (59%), Gaps = 1/137 (0%)
Frame = -3
Query: 614 AVXKLRYMQFREQRSSSAEQGFRIEAVKLPGEPALTDLQKIREPHQLAATVARFLGNDER 435
AV K RYMQ+RE SS++ GFRIE +K T+ +K + Q+ + F+ D
Sbjct: 1 AVTKPRYMQWRETMSSTSTLGFRIEGIKKADGTCNTNFKKTQALEQVTKVLEDFVDGDHV 60
Query: 434 ARREIASRLREIRDHFERSDFFKSHEIVGSSIFIIYDDERVG-AWLIDFAKTRKIPTGSQ 258
++ + L E+R+ E S FFK+HE+VGSS+ ++D + W+IDF KT +P
Sbjct: 61 ILQKYVACLEELREALEISPFFKTHEVVGSSLLFVHDHTGLAKVWMIDFGKTVALPDHQT 120
Query: 257 VNHRAPWQQGNHEEGFL 207
++HR PW +GN E+G+L
Sbjct: 121 LSHRLPWAEGNREDGYL 137
>BC033516-1|AAH33516.1| 336|Homo sapiens TBC1 domain family, member
21 protein.
Length = 336
Score = 35.1 bits (77), Expect = 0.23
Identities = 27/91 (29%), Positives = 46/91 (50%), Gaps = 1/91 (1%)
Frame = -3
Query: 467 TVARFLGNDERARREIASRLREIRDHFERSDFFKSHEIVGSSIFIIYDDERVGAWLIDFA 288
TV + +A ++ +++ + ++ R+ F ++ + I IYD + +G LID
Sbjct: 85 TVDSMRRKNYKALCQMYEKIQPLLENLHRN-FTETRNNIARDIQKIYDKDPLGNVLIDKK 143
Query: 287 KTRKIPTGSQV-NHRAPWQQGNHEEGFLFGL 198
+ KI S V N +A +QQG HE LF L
Sbjct: 144 RLEKILLLSYVCNTQAEYQQGFHEMMMLFQL 174
>AY143550-1|AAN38838.1| 1406|Homo sapiens ubiquitin-specific protease
USP6 protein.
Length = 1406
Score = 31.5 bits (68), Expect = 2.9
Identities = 23/84 (27%), Positives = 36/84 (42%), Gaps = 2/84 (2%)
Frame = -3
Query: 284 TRKIPTGSQVNHRAPWQQGNHEEGFLFGLDRLIQTIETAKLSPQGDE--VVEEPDVSR*T 111
T K T VN P + G++ + R + E LSPQ + + P + T
Sbjct: 849 TEKNFTNGMVNGHMPSLPDSPFTGYIIAVHRKMMRTELYFLSPQENRPSLFGMPLIVPCT 908
Query: 110 IKARRPWSRPTVVVTVHWLSRPVP 39
+ R+ V + V WL+RP+P
Sbjct: 909 VHTRKKDLYDAVWIQVSWLARPLP 932
>X63547-2|CAA45111.1| 1089|Homo sapiens oncogene protein.
Length = 1089
Score = 29.9 bits (64), Expect = 8.8
Identities = 22/84 (26%), Positives = 36/84 (42%), Gaps = 2/84 (2%)
Frame = -3
Query: 284 TRKIPTGSQVNHRAPWQQGNHEEGFLFGLDRLIQTIETAKLSPQGDE--VVEEPDVSR*T 111
T K T VN P + G++ + R + E LSPQ + + P + T
Sbjct: 532 TEKNFTNGMVNGHMPSLPDSPFTGYIIAVHRKMMRTELYFLSPQENRPSLFGMPLIVPCT 591
Query: 110 IKARRPWSRPTVVVTVHWLSRPVP 39
+ ++ V + V WL+RP+P
Sbjct: 592 VHTQKKDLYDAVWIQVSWLARPLP 615
>X63546-2|CAA45109.1| 586|Homo sapiens oncogene protein.
Length = 586
Score = 29.9 bits (64), Expect = 8.8
Identities = 22/84 (26%), Positives = 36/84 (42%), Gaps = 2/84 (2%)
Frame = -3
Query: 284 TRKIPTGSQVNHRAPWQQGNHEEGFLFGLDRLIQTIETAKLSPQGDE--VVEEPDVSR*T 111
T K T VN P + G++ + R + E LSPQ + + P + T
Sbjct: 29 TEKNFTNGMVNGHMPSLPDSPFTGYIIAVHRKMMRTELYFLSPQENRPSLFGMPLIVPCT 88
Query: 110 IKARRPWSRPTVVVTVHWLSRPVP 39
+ ++ V + V WL+RP+P
Sbjct: 89 VHTQKKDLYDAVWIQVSWLARPLP 112
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 100,697,850
Number of Sequences: 237096
Number of extensions: 2094014
Number of successful extensions: 4743
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 4556
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4732
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 7727256732
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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