Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P09_pT_F17
(766 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_UPI0000D573A2 Cluster: PREDICTED: similar to CG10849-PA... 196 4e-49
UniRef50_Q9NZ01 Cluster: Synaptic glycoprotein SC2; n=29; Eumeta... 159 5e-38
UniRef50_Q52L67 Cluster: Gpsn2 protein; n=30; Coelomata|Rep: Gps... 159 9e-38
UniRef50_Q5XJA6 Cluster: Zgc:103479; n=3; Euteleostomi|Rep: Zgc:... 149 7e-35
UniRef50_Q5DAJ9 Cluster: SJCHGC06367 protein; n=1; Schistosoma j... 129 9e-29
UniRef50_Q55C17 Cluster: Putative uncharacterized protein; n=1; ... 125 1e-27
UniRef50_Q4P8E1 Cluster: Putative uncharacterized protein; n=1; ... 107 3e-22
UniRef50_Q5CTX4 Cluster: Steroid reductase like intregral membra... 95 2e-18
UniRef50_O94511 Cluster: Enoyl reductase; n=1; Schizosaccharomyc... 90 6e-17
UniRef50_Q9M2U2 Cluster: Glycoprotein-like; n=8; Viridiplantae|R... 88 3e-16
UniRef50_UPI0000499F32 Cluster: steroid 5-alpha reductase; n=2; ... 83 7e-15
UniRef50_Q6CHU1 Cluster: Similar to tr|O94511 Schizosaccharomyce... 81 4e-14
UniRef50_A1CI16 Cluster: Steroid alpha reductase family protein;... 80 5e-14
UniRef50_UPI00006CDA31 Cluster: 3-oxo-5-alpha-steroid 4-dehydrog... 75 2e-12
UniRef50_Q4MZ35 Cluster: 3-oxo-5-alpha-steroid 4-dehydrogenase, ... 73 8e-12
UniRef50_A6N084 Cluster: Synaptic glycoprotein sc2; n=2; Oryza s... 72 2e-11
UniRef50_Q4Q9R2 Cluster: 3-oxo-5-alpha-steroid 4-dehydrogenase, ... 71 2e-11
UniRef50_Q7QPL2 Cluster: GLP_333_6491_6808; n=1; Giardia lamblia... 69 1e-10
UniRef50_A6RU06 Cluster: Putative uncharacterized protein; n=2; ... 68 3e-10
UniRef50_A4R7H3 Cluster: Putative uncharacterized protein; n=1; ... 68 3e-10
UniRef50_Q6BXQ9 Cluster: Debaryomyces hansenii chromosome B of s... 64 4e-09
UniRef50_Q873J6 Cluster: Putative uncharacterized protein B9B11.... 63 8e-09
UniRef50_A6QWB3 Cluster: Predicted protein; n=1; Ajellomyces cap... 62 1e-08
UniRef50_A2EPB0 Cluster: 3-oxo-5-alpha-steroid 4-dehydrogenase f... 61 3e-08
UniRef50_Q20344 Cluster: Putative uncharacterized protein; n=3; ... 56 1e-06
UniRef50_A0D5G2 Cluster: Chromosome undetermined scaffold_38, wh... 55 2e-06
UniRef50_A7RX92 Cluster: Predicted protein; n=1; Nematostella ve... 54 5e-06
UniRef50_P31213 Cluster: 3-oxo-5-alpha-steroid 4-dehydrogenase 2... 53 9e-06
UniRef50_A6G326 Cluster: Putative membrane dehydrogenase protein... 52 2e-05
UniRef50_Q5YR21 Cluster: Putative steroid dehydrogenase; n=2; Co... 47 4e-04
UniRef50_Q99190 Cluster: Enoyl reductase TSC13; n=6; Saccharomyc... 47 4e-04
UniRef50_P18405 Cluster: 3-oxo-5-alpha-steroid 4-dehydrogenase 1... 45 0.002
UniRef50_A7RP43 Cluster: Predicted protein; n=2; Nematostella ve... 44 0.005
UniRef50_Q5KGZ8 Cluster: Putative uncharacterized protein; n=2; ... 43 0.007
UniRef50_Q9UT20 Cluster: Steroid reductase; n=1; Schizosaccharom... 43 0.010
UniRef50_A4GI04 Cluster: Putative uncharacterized protein; n=1; ... 42 0.017
UniRef50_Q9LFS3 Cluster: Steroid 5alpha-reductase-like protein; ... 42 0.017
UniRef50_Q6SH56 Cluster: Steroid 5-alpha reductase family protei... 42 0.022
UniRef50_Q23431 Cluster: Putative uncharacterized protein; n=2; ... 41 0.039
UniRef50_A0BR98 Cluster: Chromosome undetermined scaffold_122, w... 41 0.039
UniRef50_A7SFY9 Cluster: Predicted protein; n=1; Nematostella ve... 39 0.12
UniRef50_A5P505 Cluster: Cytochrome c biogenesis protein, transm... 39 0.16
UniRef50_Q24HG9 Cluster: 3-oxo-5-alpha-steroid 4-dehydrogenase f... 38 0.21
UniRef50_UPI0000499497 Cluster: hypothetical protein 153.t00004;... 38 0.36
UniRef50_UPI0000E45E60 Cluster: PREDICTED: hypothetical protein;... 37 0.63
UniRef50_Q53NE6 Cluster: 3-oxo-5-alpha-steroid 4-dehydrogenase, ... 35 2.5
UniRef50_Q7JLP4 Cluster: Putative uncharacterized protein; n=3; ... 34 3.4
UniRef50_A6GFR1 Cluster: Putative steroid dehydrogenase; n=1; Pl... 34 4.4
UniRef50_A5K3J7 Cluster: 3-oxo-5-alpha-steroid 4-dehydrogenase f... 34 4.4
UniRef50_Q9CAH5 Cluster: Putative uncharacterized protein F28P22... 33 5.9
UniRef50_A4RTU4 Cluster: Predicted protein; n=2; Ostreococcus|Re... 33 5.9
UniRef50_UPI00004D9DE5 Cluster: UPI00004D9DE5 related cluster; n... 33 7.8
UniRef50_Q2FAX4 Cluster: Rh2; n=2; Cercopithecine herpesvirus 8|... 33 7.8
UniRef50_Q9WUP4 Cluster: SRD5A2L; n=24; Tetrapoda|Rep: SRD5A2L -... 33 7.8
UniRef50_Q4N2Y4 Cluster: Putative uncharacterized protein; n=1; ... 33 7.8
UniRef50_Q38944 Cluster: Probable steroid reductase DET2; n=13; ... 33 7.8
>UniRef50_UPI0000D573A2 Cluster: PREDICTED: similar to CG10849-PA;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
CG10849-PA - Tribolium castaneum
Length = 330
Score = 196 bits (479), Expect = 4e-49
Identities = 82/125 (65%), Positives = 102/125 (81%)
Frame = -1
Query: 763 AYHVNHPLYTAPCTTCYYIGLGGFVLCELGNLSIHILLKNLRPPGTKIRRIPKPDGNPFS 584
AYHVNHPL+TAP +++G+ F+ CELGNLSIHILL+NLRP G+ +R+IP PD NPF+
Sbjct: 200 AYHVNHPLHTAPPKWLFHLGVFIFIFCELGNLSIHILLRNLRPEGSTVRKIPVPDSNPFT 259
Query: 583 LLLNFVSCPNYTYEFGSWLFFTIMTKCAPAGLFAAAGFYQMAVWAIGKHRNYKKEFPDYP 404
L N+VSCPNYTYEFGSW+ FT++T C P +FA AG YQM VWAIGKH+ Y++EFP+YP
Sbjct: 260 KLFNYVSCPNYTYEFGSWVGFTLLTGCFPVFIFALAGLYQMTVWAIGKHKKYRQEFPNYP 319
Query: 403 KGRKA 389
K RKA
Sbjct: 320 KKRKA 324
>UniRef50_Q9NZ01 Cluster: Synaptic glycoprotein SC2; n=29;
Eumetazoa|Rep: Synaptic glycoprotein SC2 - Homo sapiens
(Human)
Length = 308
Score = 159 bits (387), Expect = 5e-38
Identities = 70/122 (57%), Positives = 86/122 (70%), Gaps = 2/122 (1%)
Frame = -1
Query: 763 AYHVNHPLYTAPCTTCYYI--GLGGFVLCELGNLSIHILLKNLRPPGTKIRRIPKPDGNP 590
AY++NHPLYT P + L FV+C+LGN SIH+ L++LRP G+K R+IP P NP
Sbjct: 176 AYYINHPLYTPPTYGAQQVKLALAIFVICQLGNFSIHMALRDLRPAGSKTRKIPYPTKNP 235
Query: 589 FSLLLNFVSCPNYTYEFGSWLFFTIMTKCAPAGLFAAAGFYQMAVWAIGKHRNYKKEFPD 410
F+ L VSCPNYTYE GSW+ F IMT+C P LF+ GF QM +WA GKHR+Y KEF D
Sbjct: 236 FTWLFLLVSCPNYTYEVGSWIGFAIMTQCLPVALFSLVGFTQMTIWAKGKHRSYLKEFRD 295
Query: 409 YP 404
YP
Sbjct: 296 YP 297
>UniRef50_Q52L67 Cluster: Gpsn2 protein; n=30; Coelomata|Rep: Gpsn2
protein - Mus musculus (Mouse)
Length = 362
Score = 159 bits (385), Expect = 9e-38
Identities = 69/122 (56%), Positives = 86/122 (70%), Gaps = 2/122 (1%)
Frame = -1
Query: 763 AYHVNHPLYTAPCTTCYYI--GLGGFVLCELGNLSIHILLKNLRPPGTKIRRIPKPDGNP 590
AY++NHPLYT P + L FV+C+LGN SIH+ L++LRP G+K R+IP P NP
Sbjct: 230 AYYINHPLYTPPTYGVQQVKLALAVFVICQLGNFSIHMALRDLRPAGSKTRKIPYPTKNP 289
Query: 589 FSLLLNFVSCPNYTYEFGSWLFFTIMTKCAPAGLFAAAGFYQMAVWAIGKHRNYKKEFPD 410
F+ L VSCPNYTYE GSW+ F I+T+C P LF+ GF QM +WA GKHR+Y KEF D
Sbjct: 290 FTWLFLLVSCPNYTYEVGSWIGFAILTQCVPVALFSLVGFTQMTIWAKGKHRSYLKEFRD 349
Query: 409 YP 404
YP
Sbjct: 350 YP 351
>UniRef50_Q5XJA6 Cluster: Zgc:103479; n=3; Euteleostomi|Rep:
Zgc:103479 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 349
Score = 149 bits (361), Expect = 7e-35
Identities = 68/128 (53%), Positives = 84/128 (65%), Gaps = 3/128 (2%)
Frame = -1
Query: 763 AYHVNHPLYTAPCT---TCYYIGLGGFVLCELGNLSIHILLKNLRPPGTKIRRIPKPDGN 593
AY++NHPLYT P T Y L F+LCE GNLS+H++L + G+K IP P N
Sbjct: 217 AYYINHPLYT-PATYGRLQIYSALALFLLCEFGNLSVHLILNRISCNGSKPTEIPYPTNN 275
Query: 592 PFSLLLNFVSCPNYTYEFGSWLFFTIMTKCAPAGLFAAAGFYQMAVWAIGKHRNYKKEFP 413
PF+ L FVSCPNYTYE GSW+ F +MT+C P G+FA F QM +WA KH+ Y KEF
Sbjct: 276 PFTWLFFFVSCPNYTYEVGSWISFAVMTQCVPVGVFAFLSFIQMTIWARAKHKTYVKEFK 335
Query: 412 DYPKGRKA 389
DYP+ R A
Sbjct: 336 DYPELRTA 343
>UniRef50_Q5DAJ9 Cluster: SJCHGC06367 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC06367 protein - Schistosoma
japonicum (Blood fluke)
Length = 310
Score = 129 bits (311), Expect = 9e-29
Identities = 64/127 (50%), Positives = 82/127 (64%), Gaps = 3/127 (2%)
Frame = -1
Query: 760 YHVNHPLYTAPCT--TCYYIGLGGFVLCELGNLSIHILLKNLRPPGTKIRRIPKP-DGNP 590
Y NH LYT P T IG F++ E GN S H+ LK LRP GT +R+IP P G
Sbjct: 178 YFTNHHLYTPPTFGHTQILIGFFLFMIGEWGNFSCHLALKRLRPAGTTVRQIPYPMSGWF 237
Query: 589 FSLLLNFVSCPNYTYEFGSWLFFTIMTKCAPAGLFAAAGFYQMAVWAIGKHRNYKKEFPD 410
F+ + N V+CPNYTYE SW+ FTIMT+ P+ +F GF QM+VWAI K + Y++EF +
Sbjct: 238 FTRMFNLVACPNYTYEIISWIGFTIMTQTLPSLIFTICGFRQMSVWAINKLKAYRREFGN 297
Query: 409 YPKGRKA 389
+PK RKA
Sbjct: 298 FPKNRKA 304
>UniRef50_Q55C17 Cluster: Putative uncharacterized protein; n=1;
Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein - Dictyostelium discoideum AX4
Length = 300
Score = 125 bits (301), Expect = 1e-27
Identities = 62/125 (49%), Positives = 81/125 (64%), Gaps = 1/125 (0%)
Frame = -1
Query: 763 AYHVNHPLYTAPCTTCYYIGLGGFVLCELGNLSIHILLKNLRPPGTKIRRIPKPDGNPFS 584
+Y VNHPLYT Y+GLG +++ E+ N HI L+NLRP G+ R+IP+
Sbjct: 175 SYFVNHPLYTEAPIERVYLGLGLWIIGEVFNYICHIQLRNLRPAGSTERKIPR------G 228
Query: 583 LLLNFVSCPNYTYEFGSWLFFTIMTKCAPAGLFAAAGFYQMAVWAIGKHRNYKKEFPD-Y 407
LL FVSCPNYT E SW+ F+I+T+ + +FA G QM +WA+GKHR Y+KEF D Y
Sbjct: 229 LLFEFVSCPNYTVEILSWIGFSILTQTLTSWIFALMGAAQMWIWAVGKHRRYRKEFGDKY 288
Query: 406 PKGRK 392
PK RK
Sbjct: 289 PKSRK 293
>UniRef50_Q4P8E1 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 310
Score = 107 bits (257), Expect = 3e-22
Identities = 60/113 (53%), Positives = 72/113 (63%), Gaps = 1/113 (0%)
Frame = -1
Query: 724 TTCYYIGLGGFVLCELGNLSIHILLKNLRPPGTKIRRIPKPDGNPFSLLLNFVSCPNYTY 545
TT Y VL EL N HI+LKNLRP GTK+R+IP+ G F L VSCPNY +
Sbjct: 199 TTFIYSTAAVMVLAELANGYTHIILKNLRPAGTKVRKIPRGFG--FEL----VSCPNYFF 252
Query: 544 EFGSWLFFTIMTKCAPAGLFAAAGFYQMAVWAIGKHRNYKKEF-PDYPKGRKA 389
EF +W FT++T + LFAA QM VWA+ KH+NYKKEF +YPK RKA
Sbjct: 253 EFLAWAAFTVLTLNPASALFAAVSTAQMWVWAVKKHKNYKKEFGKEYPK-RKA 304
>UniRef50_Q5CTX4 Cluster: Steroid reductase like intregral membrane
protein with 4x transmembrane domains and an ubiquitin
domain at its N-terminus; n=3; Apicomplexa|Rep: Steroid
reductase like intregral membrane protein with 4x
transmembrane domains and an ubiquitin domain at its
N-terminus - Cryptosporidium parvum Iowa II
Length = 309
Score = 94.7 bits (225), Expect = 2e-18
Identities = 54/127 (42%), Positives = 72/127 (56%), Gaps = 3/127 (2%)
Frame = -1
Query: 760 YHVNHPLYTAP---CTTCYYIGLGGFVLCELGNLSIHILLKNLRPPGTKIRRIPKPDGNP 590
Y+ HP ++ P T Y+I + V L N + H++L+ LR GTK R IP G+
Sbjct: 184 YYTFHPKFSPPEFSPVTLYFIAILMCVFESL-NFNSHLVLRKLRDRGTKKRGIPY--GSG 240
Query: 589 FSLLLNFVSCPNYTYEFGSWLFFTIMTKCAPAGLFAAAGFYQMAVWAIGKHRNYKKEFPD 410
F L VSC NY +E SW+ F+ + CA L+ F QM+ WA+ KHRNY KEF +
Sbjct: 241 FDL----VSCANYFWETLSWICFSFIANCATCWLYTLIAFIQMSQWALKKHRNYHKEFAN 296
Query: 409 YPKGRKA 389
YPK RKA
Sbjct: 297 YPKHRKA 303
>UniRef50_O94511 Cluster: Enoyl reductase; n=1; Schizosaccharomyces
pombe|Rep: Enoyl reductase - Schizosaccharomyces pombe
(Fission yeast)
Length = 295
Score = 89.8 bits (213), Expect = 6e-17
Identities = 46/102 (45%), Positives = 58/102 (56%)
Frame = -1
Query: 697 GFVLCELGNLSIHILLKNLRPPGTKIRRIPKPDGNPFSLLLNFVSCPNYTYEFGSWLFFT 518
G+ L N HI+L++LRP G+K R IP G N VS PNY +E WLFF
Sbjct: 193 GWAFAVLSNFRTHIILRDLRPAGSKKRVIPTGYG------FNLVSFPNYFFESLGWLFFA 246
Query: 517 IMTKCAPAGLFAAAGFYQMAVWAIGKHRNYKKEFPDYPKGRK 392
++TK + +F G QM VWA KH Y KEFP+YP+ RK
Sbjct: 247 LLTKSWASWIFLFVGSAQMFVWAKKKHARYLKEFPNYPRSRK 288
>UniRef50_Q9M2U2 Cluster: Glycoprotein-like; n=8; Viridiplantae|Rep:
Glycoprotein-like - Arabidopsis thaliana (Mouse-ear
cress)
Length = 310
Score = 87.8 bits (208), Expect = 3e-16
Identities = 52/128 (40%), Positives = 65/128 (50%), Gaps = 7/128 (5%)
Frame = -1
Query: 763 AYHVNHPLYTAPCTTCYYIGLGGFVLCELGNLSIHILLKNLRPP-GTKIRRIPKPDGNPF 587
AY+VNHPLYT IG G ++C++ N HILLKNLR P G +IP+
Sbjct: 180 AYYVNHPLYTPVSDLQMKIGFGFGLVCQVANFYCHILLKNLRDPSGAGGYQIPR------ 233
Query: 586 SLLLNFVSCPNYTYEFGSWLFFTIMTKCAPAGLFAAAGFYQMAVWAIGKHRNYKKEF--- 416
L N V+C NYT E WL F I T+ +F A M WA+GKH +K F
Sbjct: 234 GFLFNIVTCANYTTEIYQWLGFNIATQTIAGYVFLAVAALIMTNWALGKHSRLRKIFDGK 293
Query: 415 ---PDYPK 401
P YP+
Sbjct: 294 DGKPKYPR 301
>UniRef50_UPI0000499F32 Cluster: steroid 5-alpha reductase; n=2;
Entamoeba histolytica HM-1:IMSS|Rep: steroid 5-alpha
reductase - Entamoeba histolytica HM-1:IMSS
Length = 285
Score = 83.0 bits (196), Expect = 7e-15
Identities = 40/110 (36%), Positives = 61/110 (55%), Gaps = 1/110 (0%)
Frame = -1
Query: 727 CTTCYYIGLGGFVLCELGNLSIHILLKNLRPPGTKIRRIPKPDGNPFSLLLNFVSCPNYT 548
C+ +GL G ++ + N H+LLK LR PG++ ++P L +++C NY
Sbjct: 173 CSILIILGLIGMIVSIISNGYCHLLLKQLRTPGSQEWKMPH------GFLFEYITCANYF 226
Query: 547 YEFGSWLFFTIMTKCAPAGL-FAAAGFYQMAVWAIGKHRNYKKEFPDYPK 401
E +W+FF +MT + G+ F+ G YQM WA +H+ Y FPDYPK
Sbjct: 227 CEIMTWIFFNVMTGFSFFGIAFSCCGIYQMREWAYQRHQKYLHMFPDYPK 276
>UniRef50_Q6CHU1 Cluster: Similar to tr|O94511 Schizosaccharomyces
pombe 3-oxo-5-alpha-steroid 4-dehydrogenase; n=1;
Yarrowia lipolytica|Rep: Similar to tr|O94511
Schizosaccharomyces pombe 3-oxo-5-alpha-steroid
4-dehydrogenase - Yarrowia lipolytica (Candida
lipolytica)
Length = 327
Score = 80.6 bits (190), Expect = 4e-14
Identities = 44/98 (44%), Positives = 54/98 (55%), Gaps = 1/98 (1%)
Frame = -1
Query: 682 ELGNLSIHILLKNLRPPGTKIRRIPKPDGNPFSLLLNFVSCPNYTYEFGSWLFFTIMTKC 503
E N H L +LR G+K +IP F N VSCPNY +E SW+ +M
Sbjct: 229 ETSNFWTHFNLASLRNDGSKDHKIP------FGYGFNLVSCPNYFFEVVSWIAIALMCGN 282
Query: 502 APAGLFAAAGFYQMAVWAIGKHRNYKKEFPD-YPKGRK 392
A +F A GF QM VWA+ KHR YK+EF D YP+ RK
Sbjct: 283 WSAYVFTAIGFGQMYVWAVQKHRRYKREFGDRYPRNRK 320
>UniRef50_A1CI16 Cluster: Steroid alpha reductase family protein;
n=10; Pezizomycotina|Rep: Steroid alpha reductase family
protein - Aspergillus clavatus
Length = 312
Score = 80.2 bits (189), Expect = 5e-14
Identities = 47/115 (40%), Positives = 62/115 (53%), Gaps = 1/115 (0%)
Frame = -1
Query: 730 PCTTCYYIGLGGFVLCELGNLSIHILLKNLRPPGTKIRRIPKPDGNPFSLLLNFVSCPNY 551
P Y GL FV EL NL+ H++L+ LR PGT R IP G N V+CPNY
Sbjct: 197 PNLALLYSGLALFVFGELANLNTHLVLRGLRRPGTTERGIPSGFG------FNLVTCPNY 250
Query: 550 TYEFGSWLFFTIMTKCA-PAGLFAAAGFYQMAVWAIGKHRNYKKEFPDYPKGRKA 389
+E +WL +++ + LF A G QMA WA K R Y+KEF D K +++
Sbjct: 251 LFEIIAWLGVYLVSGLSWSVLLFIAVGGAQMASWAAKKERRYRKEFGDKYKRKRS 305
>UniRef50_UPI00006CDA31 Cluster: 3-oxo-5-alpha-steroid
4-dehydrogenase family protein; n=1; Tetrahymena
thermophila SB210|Rep: 3-oxo-5-alpha-steroid
4-dehydrogenase family protein - Tetrahymena thermophila
SB210
Length = 309
Score = 74.9 bits (176), Expect = 2e-12
Identities = 44/113 (38%), Positives = 60/113 (53%), Gaps = 6/113 (5%)
Frame = -1
Query: 709 IGLGGFVLCELGNLSIHILLKNLRP--PGTKIR---RIPKPDGNPFSLLLNFVSCPNYTY 545
I LG + L E N H L N+R P + + K P + VSC NY +
Sbjct: 191 IWLGLWALFEFLNFQCHKTLSNIRTEVPSKTLEDGSSVNKRRKIPTGWGFDQVSCANYLW 250
Query: 544 EFGSWLFFTIMTKCAPAGLFAAAGFYQMAVWAIGKHRNYKKEF-PDYPKGRKA 389
E +W+ F+ ++C + F A FYQM VWA+GK R YKKEF ++P+GRKA
Sbjct: 251 ETLAWVAFSGFSRCYTSYFFTAISFYQMFVWALGKQRRYKKEFGKEFPRGRKA 303
>UniRef50_Q4MZ35 Cluster: 3-oxo-5-alpha-steroid 4-dehydrogenase,
putative; n=3; Piroplasmida|Rep: 3-oxo-5-alpha-steroid
4-dehydrogenase, putative - Theileria parva
Length = 296
Score = 72.9 bits (171), Expect = 8e-12
Identities = 40/102 (39%), Positives = 50/102 (49%)
Frame = -1
Query: 694 FVLCELGNLSIHILLKNLRPPGTKIRRIPKPDGNPFSLLLNFVSCPNYTYEFGSWLFFTI 515
F L + H+ L LRP GT +R IP+ G +VSC NY +E W+ +
Sbjct: 195 FFLFQFLTFMTHLTLCRLRPKGTVVRGIPRDWG------FQYVSCANYFWELLIWVDIAL 248
Query: 514 MTKCAPAGLFAAAGFYQMAVWAIGKHRNYKKEFPDYPKGRKA 389
FA A F +A WA KH Y KEFP+YPK RKA
Sbjct: 249 FVNTLTGYFFAFAVFLILANWAKKKHNKYLKEFPNYPKNRKA 290
>UniRef50_A6N084 Cluster: Synaptic glycoprotein sc2; n=2; Oryza
sativa|Rep: Synaptic glycoprotein sc2 - Oryza sativa
subsp. indica (Rice)
Length = 110
Score = 71.7 bits (168), Expect = 2e-11
Identities = 43/103 (41%), Positives = 54/103 (52%), Gaps = 2/103 (1%)
Frame = -1
Query: 697 GF-VLCELGNLSIHILLKNLRPP-GTKIRRIPKPDGNPFSLLLNFVSCPNYTYEFGSWLF 524
GF +LC++ N HILL+NLR P G +IP+ L N V+C NYT E WL
Sbjct: 1 GFGILCQIANFYCHILLRNLRSPSGNGGYQIPR------GFLFNIVTCANYTTEIYQWLG 54
Query: 523 FTIMTKCAPAGLFAAAGFYQMAVWAIGKHRNYKKEFPDYPKGR 395
F I T+ +F M WA+GKHR KK F D +GR
Sbjct: 55 FNIATQTVAGYIFLVVAASIMTNWALGKHRRLKKLF-DGKEGR 96
>UniRef50_Q4Q9R2 Cluster: 3-oxo-5-alpha-steroid 4-dehydrogenase,
putative; n=5; Trypanosomatidae|Rep:
3-oxo-5-alpha-steroid 4-dehydrogenase, putative -
Leishmania major
Length = 306
Score = 71.3 bits (167), Expect = 2e-11
Identities = 45/117 (38%), Positives = 57/117 (48%), Gaps = 1/117 (0%)
Frame = -1
Query: 760 YHVNHPLYTAPCTTCYYIGLGGFVLCELGNLSIHILLKNLRPP-GTKIRRIPKPDGNPFS 584
Y + P +T T G V+ EL N ++H L +R G R +P+ P
Sbjct: 183 YVLCSPSFTPTSTMQSNFGAVVMVINELLNFAVHYQLSTMRKSDGDTTRNVPQ---GP-- 237
Query: 583 LLLNFVSCPNYTYEFGSWLFFTIMTKCAPAGLFAAAGFYQMAVWAIGKHRNYKKEFP 413
L FVSCPNY +E SW+ F+I T + F AGF QMA WA KHR Y K P
Sbjct: 238 -LFAFVSCPNYFFEIMSWVSFSIGTNMLSSWFFTLAGFVQMADWAKKKHRGYVKADP 293
>UniRef50_Q7QPL2 Cluster: GLP_333_6491_6808; n=1; Giardia lamblia
ATCC 50803|Rep: GLP_333_6491_6808 - Giardia lamblia ATCC
50803
Length = 105
Score = 69.3 bits (162), Expect = 1e-10
Identities = 35/98 (35%), Positives = 52/98 (53%)
Frame = -1
Query: 694 FVLCELGNLSIHILLKNLRPPGTKIRRIPKPDGNPFSLLLNFVSCPNYTYEFGSWLFFTI 515
F + EL NL H+ L+ LRPPG++ +P+ LL + ++CPNYT E SW+ F +
Sbjct: 6 FFVSELCNLYCHLKLRYLRPPGSREHFLPR------GLLFDRITCPNYTTEILSWMSFAM 59
Query: 514 MTKCAPAGLFAAAGFYQMAVWAIGKHRNYKKEFPDYPK 401
T+ +F G QM +WA K +FP+ K
Sbjct: 60 FTRSWVCAVFNVCGAVQMYIWARQKRARLATQFPEVKK 97
>UniRef50_A6RU06 Cluster: Putative uncharacterized protein; n=2;
Sclerotiniaceae|Rep: Putative uncharacterized protein -
Botryotinia fuckeliana B05.10
Length = 319
Score = 67.7 bits (158), Expect = 3e-10
Identities = 40/105 (38%), Positives = 56/105 (53%), Gaps = 1/105 (0%)
Frame = -1
Query: 706 GLGGFVLCELGNLSIHILLKNLRPPGTKIRRIPKPDGNPFSLLLNFVSCPNYTYEFGSWL 527
G+ ++ EL NL H+ L NLR PG R IP+ G FS+ V+CPNY +E +W+
Sbjct: 205 GVALYLFGELSNLKTHLTLSNLRSPGGTERGIPQ--GYGFSM----VTCPNYFFETLAWI 258
Query: 526 FFTIMTKCAPAGLFAAAGFYQMAVWAIGKHRNYKKEFPD-YPKGR 395
++TK +FA G QM WA+ K + +F D Y K R
Sbjct: 259 GMILVTKSLSTVIFAIVGTAQMQQWAVKKENPSRVDFGDKYKKKR 303
>UniRef50_A4R7H3 Cluster: Putative uncharacterized protein; n=1;
Magnaporthe grisea|Rep: Putative uncharacterized protein
- Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 338
Score = 67.7 bits (158), Expect = 3e-10
Identities = 39/107 (36%), Positives = 58/107 (54%), Gaps = 1/107 (0%)
Frame = -1
Query: 712 YIGLGGFVLCELGNLSIHILLKNLRPPGTKIRRIPKPDGNPFSLLLNFVSCPNYTYEFGS 533
Y+GL FV EL N +H+ L NLR PGT + IP G+ + V+CPNY +E +
Sbjct: 230 YLGLALFVYGELCNGIVHLHLANLRAPGTTEKGIPSCVGS------SVVTCPNYMFEVIA 283
Query: 532 WLFFTIMTKCAPAGLFAAAGFYQMAVWAIGKHRNYKKEFPD-YPKGR 395
W+ ++++ + G Y M +W+I K R ++ FPD Y K R
Sbjct: 284 WVGMIMVSRSWATVITIVMGGYYMMIWSIQKERALRQLFPDKYKKKR 330
>UniRef50_Q6BXQ9 Cluster: Debaryomyces hansenii chromosome B of
strain CBS767 of Debaryomyces hansenii; n=7;
Saccharomycetales|Rep: Debaryomyces hansenii chromosome
B of strain CBS767 of Debaryomyces hansenii -
Debaryomyces hansenii (Yeast) (Torulaspora hansenii)
Length = 316
Score = 64.1 bits (149), Expect = 4e-09
Identities = 38/105 (36%), Positives = 56/105 (53%), Gaps = 1/105 (0%)
Frame = -1
Query: 712 YIGLGGFVLCELGNLSIHILLKNLRPPGTKIRRIPKPDGNPFSLLLNFVSCPNYTYEFGS 533
Y+ G ++ EL N + H+ L +LR + R P G F ++VSCPNY +E S
Sbjct: 206 YMLAGLWLFAELSNFATHLNLASLRS-SSNTRNYVIPYGYGF----DWVSCPNYFFESLS 260
Query: 532 WLFFTIMTKCAPAGLFAAAGFYQMAVWAIGKHRNYKKEF-PDYPK 401
WLF+ ++ + +F A QM +WA+ KH+ Y K F DY K
Sbjct: 261 WLFYALLVGNWSSWVFLAVATGQMWLWAVKKHKRYLKTFGDDYKK 305
>UniRef50_Q873J6 Cluster: Putative uncharacterized protein
B9B11.030; n=3; Sordariomycetes|Rep: Putative
uncharacterized protein B9B11.030 - Neurospora crassa
Length = 316
Score = 62.9 bits (146), Expect = 8e-09
Identities = 35/107 (32%), Positives = 53/107 (49%)
Frame = -1
Query: 712 YIGLGGFVLCELGNLSIHILLKNLRPPGTKIRRIPKPDGNPFSLLLNFVSCPNYTYEFGS 533
Y G+ F +CE N +H L +LR PG R IP G+ N V+ PNY +E +
Sbjct: 208 YFGIALFAVCEACNWIVHQHLASLRKPGGTERGIPNCIGS------NLVTSPNYMFEVLA 261
Query: 532 WLFFTIMTKCAPAGLFAAAGFYQMAVWAIGKHRNYKKEFPDYPKGRK 392
W+ ++++ +F A G M W+ GK R + EF D K ++
Sbjct: 262 WVGVILISRSPAVVIFIATGTIYMRSWSRGKERALRNEFGDRYKAKR 308
>UniRef50_A6QWB3 Cluster: Predicted protein; n=1; Ajellomyces
capsulatus NAm1|Rep: Predicted protein - Ajellomyces
capsulatus NAm1
Length = 197
Score = 62.1 bits (144), Expect = 1e-08
Identities = 40/102 (39%), Positives = 53/102 (51%), Gaps = 2/102 (1%)
Frame = -1
Query: 694 FVLCELGNLSIHILLKNLRPPGTKIRRIPKPDGNPFSLLLNFVSCPNYTYEFGSWL-FFT 518
FV +L NL+ H++L+NLR PGT R I P G FSL V+CPNY +E +W+ +
Sbjct: 98 FVFGQLANLNSHVVLRNLRRPGTSERGI--PSGFGFSL----VTCPNYLFEVIAWVGVYL 151
Query: 517 IMTKCAPAGLFAAAGFYQMAVWAIGKHRNYKKEFPD-YPKGR 395
+ LF M +W K R Y+ EF D Y K R
Sbjct: 152 VSGLNWSMVLFIVVACTPMIIWGKQKERAYRTEFGDKYKKKR 193
>UniRef50_A2EPB0 Cluster: 3-oxo-5-alpha-steroid 4-dehydrogenase
family protein; n=3; Trichomonas vaginalis G3|Rep:
3-oxo-5-alpha-steroid 4-dehydrogenase family protein -
Trichomonas vaginalis G3
Length = 284
Score = 61.3 bits (142), Expect = 3e-08
Identities = 34/103 (33%), Positives = 52/103 (50%)
Frame = -1
Query: 718 CYYIGLGGFVLCELGNLSIHILLKNLRPPGTKIRRIPKPDGNPFSLLLNFVSCPNYTYEF 539
C I + + + E N H L +LRP G+K R +PK L N ++ PNYT+E
Sbjct: 175 CQIIAIPLWFVSECLNFYCHYTLAHLRPKGSKERFLPK------GFLFNRITSPNYTFEI 228
Query: 538 GSWLFFTIMTKCAPAGLFAAAGFYQMAVWAIGKHRNYKKEFPD 410
+FF + T+ A +FA G M + A K ++Y K +P+
Sbjct: 229 SGCIFFAVYTRLITAVIFATVGGSYMLMCAHQKRKSYIKRWPE 271
>UniRef50_Q20344 Cluster: Putative uncharacterized protein; n=3;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 243
Score = 55.6 bits (128), Expect = 1e-06
Identities = 32/89 (35%), Positives = 43/89 (48%)
Frame = -1
Query: 655 LLKNLRPPGTKIRRIPKPDGNPFSLLLNFVSCPNYTYEFGSWLFFTIMTKCAPAGLFAAA 476
+L LR PG +IP L ++SCPNY E W+ + I+ PA FA
Sbjct: 155 ILMTLRKPGETGYKIPT------GFLYEYISCPNYFGEIMEWIGYAILGWNLPALAFAIF 208
Query: 475 GFYQMAVWAIGKHRNYKKEFPDYPKGRKA 389
F + AI H YK++FP YP R+A
Sbjct: 209 TFANIGPRAIAHHNWYKEKFPKYPPTRRA 237
>UniRef50_A0D5G2 Cluster: Chromosome undetermined scaffold_38, whole
genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_38,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 309
Score = 55.2 bits (127), Expect = 2e-06
Identities = 29/69 (42%), Positives = 37/69 (53%), Gaps = 1/69 (1%)
Frame = -1
Query: 592 PFSLLLNFVSCPNYTYEFGSWLFFTIMTKCAPAGLFAAAGFYQMAVWAIGKHRNYKKEFP 413
P+ VS NY +E +W+ F++ T A F F QM +WA KHR Y KEF
Sbjct: 235 PYGWGFGAVSSANYFWETMAWVSFSLFTCSYAAIAFTIFSFGQMLIWAKQKHRRYIKEFG 294
Query: 412 D-YPKGRKA 389
D YP+ RKA
Sbjct: 295 DRYPRNRKA 303
>UniRef50_A7RX92 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 127
Score = 53.6 bits (123), Expect = 5e-06
Identities = 37/109 (33%), Positives = 51/109 (46%)
Frame = -1
Query: 715 YYIGLGGFVLCELGNLSIHILLKNLRPPGTKIRRIPKPDGNPFSLLLNFVSCPNYTYEFG 536
+ +G F+L N I L+ LRP + +PK G PF L VSCPNY E
Sbjct: 19 FILGAALFLLGFCINRYADIKLRMLRPDESSGYAVPK--GGPFEL----VSCPNYFGEML 72
Query: 535 SWLFFTIMTKCAPAGLFAAAGFYQMAVWAIGKHRNYKKEFPDYPKGRKA 389
W + + T A ++ G A+ H+ YK FPDYP+ R+A
Sbjct: 73 EWFGWALCTWSAAGLVWFLFGCGTFIPRAMHNHKWYKDRFPDYPQKRRA 121
>UniRef50_P31213 Cluster: 3-oxo-5-alpha-steroid 4-dehydrogenase 2;
n=26; Euteleostomi|Rep: 3-oxo-5-alpha-steroid
4-dehydrogenase 2 - Homo sapiens (Human)
Length = 254
Score = 52.8 bits (121), Expect = 9e-06
Identities = 36/109 (33%), Positives = 51/109 (46%)
Frame = -1
Query: 715 YYIGLGGFVLCELGNLSIHILLKNLRPPGTKIRRIPKPDGNPFSLLLNFVSCPNYTYEFG 536
+ +G+ F+L N+ +L+ LR PG RIP+ L +VS N+ E
Sbjct: 146 FSLGVFLFILGMGINIHSDYILRQLRKPGEISYRIPQGG------LFTYVSGANFLGEII 199
Query: 535 SWLFFTIMTKCAPAGLFAAAGFYQMAVWAIGKHRNYKKEFPDYPKGRKA 389
W+ + + T PA FA + + A HR Y K F DYPK RKA
Sbjct: 200 EWIGYALATWSLPALAFAFFSLCFLGLRAFHHHRFYLKMFEDYPKSRKA 248
>UniRef50_A6G326 Cluster: Putative membrane dehydrogenase protein;
n=1; Plesiocystis pacifica SIR-1|Rep: Putative membrane
dehydrogenase protein - Plesiocystis pacifica SIR-1
Length = 256
Score = 51.6 bits (118), Expect = 2e-05
Identities = 35/108 (32%), Positives = 46/108 (42%)
Frame = -1
Query: 712 YIGLGGFVLCELGNLSIHILLKNLRPPGTKIRRIPKPDGNPFSLLLNFVSCPNYTYEFGS 533
++G G F+ N +L LR PG +IP+ L +VSCPNY E
Sbjct: 149 WLGAGMFLAGWAINFKADAMLIALREPGESGYKIPR------GWLYEYVSCPNYLGEILE 202
Query: 532 WLFFTIMTKCAPAGLFAAAGFYQMAVWAIGKHRNYKKEFPDYPKGRKA 389
W + + T P FA + A HR Y+ F DYP RKA
Sbjct: 203 WTGWAVATWSLPGLAFALYTAANIGPRARSNHRWYQATFEDYPPERKA 250
>UniRef50_Q5YR21 Cluster: Putative steroid dehydrogenase; n=2;
Corynebacterineae|Rep: Putative steroid dehydrogenase -
Nocardia farcinica
Length = 263
Score = 47.2 bits (107), Expect = 4e-04
Identities = 37/113 (32%), Positives = 50/113 (44%), Gaps = 4/113 (3%)
Frame = -1
Query: 715 YYIGLGGFVLCELGNL----SIHILLKNLRPPGTKIRRIPKPDGNPFSLLLNFVSCPNYT 548
+ IGL G+ LC L SI L++ R PG RIP G FVS P Y
Sbjct: 152 FLIGLAGY-LCGFALLVRSESIVRNLRDKRDPGAAEYRIPYGGG------FRFVSSPAYL 204
Query: 547 YEFGSWLFFTIMTKCAPAGLFAAAGFYQMAVWAIGKHRNYKKEFPDYPKGRKA 389
E +W F ++T + + A HR Y+++F DYP+ RKA
Sbjct: 205 GELIAWAGFALLTWSLAGVVIFLITAGNLVPRAFATHRWYREKFADYPRNRKA 257
>UniRef50_Q99190 Cluster: Enoyl reductase TSC13; n=6;
Saccharomycetales|Rep: Enoyl reductase TSC13 -
Saccharomyces cerevisiae (Baker's yeast)
Length = 310
Score = 47.2 bits (107), Expect = 4e-04
Identities = 34/97 (35%), Positives = 45/97 (46%), Gaps = 5/97 (5%)
Frame = -1
Query: 703 LGGFVLCELGNLSIHILLK----NLRPPGTKIRRIPKPDGNPFSLLLNFVSCPNYTYEFG 536
+G FVL EL N HI L+ + G R+P G + N PNYT+E
Sbjct: 207 IGLFVLSELWNFYCHIKLRLWGDYQKKHGNAKIRVPLNQG-----IFNLFVAPNYTFEVW 261
Query: 535 SWLFFTIMTKC-APAGLFAAAGFYQMAVWAIGKHRNY 428
SW++FT + K A LF QM WA K++ Y
Sbjct: 262 SWIWFTFVFKFNLFAVLFLTVSTAQMYAWAQKKNKKY 298
>UniRef50_P18405 Cluster: 3-oxo-5-alpha-steroid 4-dehydrogenase 1;
n=25; Euteleostomi|Rep: 3-oxo-5-alpha-steroid
4-dehydrogenase 1 - Homo sapiens (Human)
Length = 259
Score = 44.8 bits (101), Expect = 0.002
Identities = 31/108 (28%), Positives = 49/108 (45%)
Frame = -1
Query: 715 YYIGLGGFVLCELGNLSIHILLKNLRPPGTKIRRIPKPDGNPFSLLLNFVSCPNYTYEFG 536
+ IG G ++ L N+ +L+NLR PG +IP+ L +V+ NY E
Sbjct: 151 FLIGFGLWLTGMLINIHSDHILRNLRKPGDTGYKIPRGG------LFEYVTAANYFGEIM 204
Query: 535 SWLFFTIMTKCAPAGLFAAAGFYQMAVWAIGKHRNYKKEFPDYPKGRK 392
W + + + FA F ++ A H Y ++F +YPK RK
Sbjct: 205 EWCGYALASWSVQGAAFAFFTFCFLSGRAKEHHEWYLRKFEEYPKFRK 252
>UniRef50_A7RP43 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 231
Score = 43.6 bits (98), Expect = 0.005
Identities = 29/95 (30%), Positives = 43/95 (45%)
Frame = -1
Query: 673 NLSIHILLKNLRPPGTKIRRIPKPDGNPFSLLLNFVSCPNYTYEFGSWLFFTIMTKCAPA 494
N+ +L +LR PG +IP+ L +VS N+ E W F + + P
Sbjct: 137 NIQSDNILTSLRKPGEVGYKIPRGG------LFEYVSGANFCSEILEWSGFALASCSYPG 190
Query: 493 GLFAAAGFYQMAVWAIGKHRNYKKEFPDYPKGRKA 389
+A + AI H+ Y ++F DYPK RKA
Sbjct: 191 FTYAFFTLCNVGPRAIQHHKFYVEKFEDYPKSRKA 225
>UniRef50_Q5KGZ8 Cluster: Putative uncharacterized protein; n=2;
Filobasidiella neoformans|Rep: Putative uncharacterized
protein - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 310
Score = 43.2 bits (97), Expect = 0.007
Identities = 29/93 (31%), Positives = 45/93 (48%), Gaps = 1/93 (1%)
Frame = -1
Query: 691 VLCELGNLSIHILLKNLRPPGTKIRRIPKPDGNPFSLLLNFVSCPNYTYEFGSWLFFTIM 512
++ EL NL+ H+ L++LR P R+ P G F + + C NY +E + M
Sbjct: 207 LVAELLNLNAHLHLRSLRQPPGHPRKFPT--GLGFGIAV----CANYWFEILGVIALVAM 260
Query: 511 TKC-APAGLFAAAGFYQMAVWAIGKHRNYKKEF 416
T ++ G + M WA GK+ YK+EF
Sbjct: 261 TGGDIGTVIYLCIGTFFMKTWADGKYTRYKREF 293
>UniRef50_Q9UT20 Cluster: Steroid reductase; n=1;
Schizosaccharomyces pombe|Rep: Steroid reductase -
Schizosaccharomyces pombe (Fission yeast)
Length = 282
Score = 42.7 bits (96), Expect = 0.010
Identities = 23/70 (32%), Positives = 32/70 (45%), Gaps = 2/70 (2%)
Frame = -1
Query: 592 PFSLLLNFVSCPNYTYEFGSWL--FFTIMTKCAPAGLFAAAGFYQMAVWAIGKHRNYKKE 419
P+ L +VSCPNY E+ W + P F + M A+ H+ Y K+
Sbjct: 207 PYGGLFQYVSCPNYFCEWIEWFGCYLAAGPSAEPFWWFFLSEILLMLPRALKAHQWYCKK 266
Query: 418 FPDYPKGRKA 389
FP YP R+A
Sbjct: 267 FPKYPANRRA 276
>UniRef50_A4GI04 Cluster: Putative uncharacterized protein; n=1;
uncultured marine bacterium EB0_39H12|Rep: Putative
uncharacterized protein - uncultured marine bacterium
EB0_39H12
Length = 252
Score = 41.9 bits (94), Expect = 0.017
Identities = 32/110 (29%), Positives = 51/110 (46%), Gaps = 1/110 (0%)
Frame = -1
Query: 715 YYIGLGGFVLCELGNLSIHILLKNLRPPGTKIRRIPKPDGNPFSLLLNFVSCPNYTYEFG 536
+ +G+ F+L L N+ +L NLR G + +PK +VS PNY E
Sbjct: 144 FIVGIIIFLLGMLINIKSDNILMNLRKSGGRGYHVPK------GFFFKYVSNPNYFGEII 197
Query: 535 SWLFFTIMTKCAPAG-LFAAAGFYQMAVWAIGKHRNYKKEFPDYPKGRKA 389
W +++++ +PAG +F + A + K PDYPK RK+
Sbjct: 198 EWFGWSLLSM-SPAGFVFFIWTTANLIPRARSNNEWSKSNIPDYPKNRKS 246
>UniRef50_Q9LFS3 Cluster: Steroid 5alpha-reductase-like protein;
n=3; core eudicotyledons|Rep: Steroid
5alpha-reductase-like protein - Arabidopsis thaliana
(Mouse-ear cress)
Length = 268
Score = 41.9 bits (94), Expect = 0.017
Identities = 34/117 (29%), Positives = 54/117 (46%), Gaps = 1/117 (0%)
Frame = -1
Query: 736 TAPCTTCYYIGLGGFVLCELGNLSIHILLKNLR-PPGTKIRRIPKPDGNPFSLLLNFVSC 560
T P G+ FV+ +GNL H+LL LR G K +IPK G F +++ C
Sbjct: 152 TEPSFDMKLAGVVMFVVGIVGNLYHHVLLAKLRKEDGKKEYKIPK--GGLFDIII----C 205
Query: 559 PNYTYEFGSWLFFTIMTKCAPAGLFAAAGFYQMAVWAIGKHRNYKKEFPDYPKGRKA 389
P+Y +E + F ++++ + FA + + Y +F D+PK KA
Sbjct: 206 PHYLFEILVFWSFFLISQTIYSFSFAMGTMLYLIGRSYATRTWYLSKFDDFPKHIKA 262
>UniRef50_Q6SH56 Cluster: Steroid 5-alpha reductase family protein;
n=2; Bacteria|Rep: Steroid 5-alpha reductase family
protein - uncultured bacterium 442
Length = 266
Score = 41.5 bits (93), Expect = 0.022
Identities = 36/108 (33%), Positives = 49/108 (45%), Gaps = 5/108 (4%)
Frame = -1
Query: 697 GFVLCELG-NLSIHI--LLKNLRP--PGTKIRRIPKPDGNPFSLLLNFVSCPNYTYEFGS 533
G ++ G L+IH +L+NLR P R P G F +V+CP Y E S
Sbjct: 157 GLIVYATGFGLNIHSDHILRNLRSKTPAPNEPRYKIPFGGAF----RWVTCPQYLGEILS 212
Query: 532 WLFFTIMTKCAPAGLFAAAGFYQMAVWAIGKHRNYKKEFPDYPKGRKA 389
+ F IMT A A + A+ HR ++K F +YP RKA
Sbjct: 213 FTGFAIMTWNLGAVFVLAMTAGNLIPRALYTHRWFRKNFDEYPPERKA 260
>UniRef50_Q23431 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 253
Score = 40.7 bits (91), Expect = 0.039
Identities = 21/62 (33%), Positives = 33/62 (53%), Gaps = 1/62 (1%)
Frame = -1
Query: 571 FVSCPNYTYEFGSWLFFTIMTKCAPAGLFAAAGFYQMAVWAIGKHRNYKKEFPD-YPKGR 395
++SCPNY E W+ + + + PA FA +A A+ H+ Y+K F + YP+ R
Sbjct: 186 YISCPNYFGECLQWIGYALAARSFPAIAFAFFIVCNLAPRAMSHHKWYQKMFGEQYPRDR 245
Query: 394 KA 389
A
Sbjct: 246 HA 247
>UniRef50_A0BR98 Cluster: Chromosome undetermined scaffold_122,
whole genome shotgun sequence; n=1; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_122,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 245
Score = 40.7 bits (91), Expect = 0.039
Identities = 29/107 (27%), Positives = 50/107 (46%)
Frame = -1
Query: 709 IGLGGFVLCELGNLSIHILLKNLRPPGTKIRRIPKPDGNPFSLLLNFVSCPNYTYEFGSW 530
+G+ F+ N+ +L+ L+ + +IP GN F L VS +Y E W
Sbjct: 139 VGILIFIYGMTSNIKCDNILRGLKKENSNEYKIPY--GNLFEL----VSSGHYLGEIIEW 192
Query: 529 LFFTIMTKCAPAGLFAAAGFYQMAVWAIGKHRNYKKEFPDYPKGRKA 389
+ +++ LF + ++ A+ H+ YK +F +YPK RKA
Sbjct: 193 FGYFLVSGQWSGFLFFFSTLSILSARAVSTHKWYKNKFDNYPKNRKA 239
>UniRef50_A7SFY9 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 176
Score = 39.1 bits (87), Expect = 0.12
Identities = 21/64 (32%), Positives = 32/64 (50%)
Frame = -1
Query: 706 GLGGFVLCELGNLSIHILLKNLRPPGTKIRRIPKPDGNPFSLLLNFVSCPNYTYEFGSWL 527
GL + + E+ N H++L NLRP G+ + P G F + + CP+Y E +WL
Sbjct: 70 GLIVYAIGEMTNFQHHLILANLRPVGSAAGKYAVPTGGLFDVAI----CPHYFGELMAWL 125
Query: 526 FFTI 515
I
Sbjct: 126 GMAI 129
>UniRef50_A5P505 Cluster: Cytochrome c biogenesis protein,
transmembrane region precursor; n=6;
Alphaproteobacteria|Rep: Cytochrome c biogenesis
protein, transmembrane region precursor -
Methylobacterium sp. 4-46
Length = 734
Score = 38.7 bits (86), Expect = 0.16
Identities = 28/77 (36%), Positives = 40/77 (51%)
Frame = -1
Query: 709 IGLGGFVLCELGNLSIHILLKNLRPPGTKIRRIPKPDGNPFSLLLNFVSCPNYTYEFGSW 530
+GL F LG L++ LL L P G +RR+P+P G L F++ P Y +W
Sbjct: 476 LGLAIFAALGLG-LALPFLLLTLWPAG--LRRLPRP-GAWMETLKGFLAFPLYATV--AW 529
Query: 529 LFFTIMTKCAPAGLFAA 479
L + + + PAGLF A
Sbjct: 530 LVWVLSQQVGPAGLFLA 546
>UniRef50_Q24HG9 Cluster: 3-oxo-5-alpha-steroid 4-dehydrogenase
family protein; n=1; Tetrahymena thermophila SB210|Rep:
3-oxo-5-alpha-steroid 4-dehydrogenase family protein -
Tetrahymena thermophila SB210
Length = 266
Score = 38.3 bits (85), Expect = 0.21
Identities = 22/62 (35%), Positives = 33/62 (53%), Gaps = 1/62 (1%)
Frame = -1
Query: 571 FVSCPNYTYEFGSWLFFTIM-TKCAPAGLFAAAGFYQMAVWAIGKHRNYKKEFPDYPKGR 395
+VS NY E W+ F I+ T LFA + ++ A+ H+ Y++ F +YPK R
Sbjct: 199 YVSQANYFGEIVEWVGFAILQTHSQMPWLFAISTLSILSSRALESHKWYQQTFKEYPKER 258
Query: 394 KA 389
KA
Sbjct: 259 KA 260
>UniRef50_UPI0000499497 Cluster: hypothetical protein 153.t00004;
n=1; Entamoeba histolytica HM-1:IMSS|Rep: hypothetical
protein 153.t00004 - Entamoeba histolytica HM-1:IMSS
Length = 287
Score = 37.5 bits (83), Expect = 0.36
Identities = 21/66 (31%), Positives = 34/66 (51%), Gaps = 3/66 (4%)
Frame = -1
Query: 592 PFSLLLNFVSCPNYTYE---FGSWLFFTIMTKCAPAGLFAAAGFYQMAVWAIGKHRNYKK 422
P L +F+SCPN +E F S++F T TK + + + M + + +H YKK
Sbjct: 214 PSKALYSFISCPNNLFEGLFFTSFMFCTSFTKTSI--ILCILNWVAMVMLSQRQHNAYKK 271
Query: 421 EFPDYP 404
F ++P
Sbjct: 272 TFKNFP 277
>UniRef50_UPI0000E45E60 Cluster: PREDICTED: hypothetical protein;
n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 186
Score = 36.7 bits (81), Expect = 0.63
Identities = 30/108 (27%), Positives = 47/108 (43%), Gaps = 2/108 (1%)
Frame = -1
Query: 706 GLGGFVLCELGNLSIHILLKNLRPPGTKIRRIPKPDGNPFSLLLNFVSCPNYTYEFGSWL 527
GL FV + H++ +LR + R P G+ F ++VSCP+Y E +
Sbjct: 77 GLLMFVWASWHHHIAHVIFASLRKTKKDVSRHMIPQGDWF----DYVSCPHYLAETLIYT 132
Query: 526 FFTIMT--KCAPAGLFAAAGFYQMAVWAIGKHRNYKKEFPDYPKGRKA 389
++ L + F ++ HR Y+ +F DYPK RKA
Sbjct: 133 SLAVILGGHHRTWWLVLSFVFSNQTAASVKVHRWYQGKFEDYPKERKA 180
>UniRef50_Q53NE6 Cluster: 3-oxo-5-alpha-steroid 4-dehydrogenase,
putative; n=5; Oryza sativa|Rep: 3-oxo-5-alpha-steroid
4-dehydrogenase, putative - Oryza sativa subsp. japonica
(Rice)
Length = 266
Score = 34.7 bits (76), Expect = 2.5
Identities = 38/120 (31%), Positives = 51/120 (42%), Gaps = 1/120 (0%)
Frame = -1
Query: 745 PLYTAPCTTCYYIGLGGFVLCELGNLSIHILLKNLRPPGTKIRRIPKPDGNPFSLLLNFV 566
PL A C +GL FV N++ L L+ G K +IPK DG L + V
Sbjct: 152 PLTVARCL----VGLALFVWGMWTNIAADRELLRLKEAG-KGYQIPK-DG-----LFDLV 200
Query: 565 SCPNYTYEFGSWLFFTIMTKCAPAGLFAAAGFYQMAVWAIGKHRNYKKEFPD-YPKGRKA 389
+CPNY E WL + ++ A F + A + Y +F D YP RKA
Sbjct: 201 ACPNYFGETVEWLGYALVAWTPAAWAFFLYTCVNLGPRARDQRLWYISKFGDKYPASRKA 260
>UniRef50_Q7JLP4 Cluster: Putative uncharacterized protein; n=3;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 342
Score = 34.3 bits (75), Expect = 3.4
Identities = 20/63 (31%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Frame = -1
Query: 574 NFVSCPNYTYEFGSWL-FFTIMTKCAPAGLFAAAGFYQMAVWAIGKHRNYKKEFPDYPKG 398
N VSCP++ +E +L F ++ A+ H Y K FP YPK
Sbjct: 274 NLVSCPHFLFEICIYLSLFLVIPDAYVYRFIIMFVCINQTFAALITHSWYHKTFPKYPKS 333
Query: 397 RKA 389
RKA
Sbjct: 334 RKA 336
>UniRef50_A6GFR1 Cluster: Putative steroid dehydrogenase; n=1;
Plesiocystis pacifica SIR-1|Rep: Putative steroid
dehydrogenase - Plesiocystis pacifica SIR-1
Length = 264
Score = 33.9 bits (74), Expect = 4.4
Identities = 19/54 (35%), Positives = 28/54 (51%)
Frame = -1
Query: 673 NLSIHILLKNLRPPGTKIRRIPKPDGNPFSLLLNFVSCPNYTYEFGSWLFFTIM 512
NL H LL NLR PG ++PK L +V+CP+Y E +W + ++
Sbjct: 169 NLHHHRLLANLREPGETGYKLPKGG------LFRWVACPHYLAEILAWWGYALV 216
>UniRef50_A5K3J7 Cluster: 3-oxo-5-alpha-steroid 4-dehydrogenase
family protein; n=2; Plasmodium|Rep:
3-oxo-5-alpha-steroid 4-dehydrogenase family protein -
Plasmodium vivax
Length = 294
Score = 33.9 bits (74), Expect = 4.4
Identities = 21/61 (34%), Positives = 29/61 (47%)
Frame = -1
Query: 694 FVLCELGNLSIHILLKNLRPPGTKIRRIPKPDGNPFSLLLNFVSCPNYTYEFGSWLFFTI 515
F+L L H+ L LRP K ++ P P L FVSCP+Y E +L F +
Sbjct: 188 FLLGTLIQYDSHVRLAKLRPKDAK--KLDNPYKVPHGGLFYFVSCPHYFAEILIYLSFLL 245
Query: 514 M 512
+
Sbjct: 246 L 246
>UniRef50_Q9CAH5 Cluster: Putative uncharacterized protein
F28P22.22; n=1; Arabidopsis thaliana|Rep: Putative
uncharacterized protein F28P22.22 - Arabidopsis thaliana
(Mouse-ear cress)
Length = 320
Score = 33.5 bits (73), Expect = 5.9
Identities = 26/93 (27%), Positives = 45/93 (48%), Gaps = 2/93 (2%)
Frame = -1
Query: 661 HILLKNLRPPGTKIRRIPKPDGNPFSLLLNFVSCPNYTYEFGSWLFFTIMTKCAPAGLFA 482
H +L +LR ++ + P G+ F + VSCP++ E +L I + ++
Sbjct: 226 HAILGSLREYPSQAKEYIIPYGDWFEM----VSCPHFLAEIVLYLGLLISSGGTDISIWL 281
Query: 481 AAGFYQMAV-WAIGK-HRNYKKEFPDYPKGRKA 389
GF + +A G+ HR Y ++F +YP R A
Sbjct: 282 LFGFVAANLTYAAGETHRWYLQKFENYPASRHA 314
>UniRef50_A4RTU4 Cluster: Predicted protein; n=2; Ostreococcus|Rep:
Predicted protein - Ostreococcus lucimarinus CCE9901
Length = 256
Score = 33.5 bits (73), Expect = 5.9
Identities = 19/60 (31%), Positives = 28/60 (46%), Gaps = 1/60 (1%)
Frame = -1
Query: 592 PFSLLLNFVSCPNYTYEFGSWLFFTIMTKCA-PAGLFAAAGFYQMAVWAIGKHRNYKKEF 416
P L N V+CP+Y E W+ F I+T A +FA F + A+ Y++ F
Sbjct: 180 PTGGLFNLVACPHYLGESIEWIGFAILTAPARSTAVFAFWTFANLFPRAVATRAYYRRRF 239
>UniRef50_UPI00004D9DE5 Cluster: UPI00004D9DE5 related cluster; n=1;
Xenopus tropicalis|Rep: UPI00004D9DE5 UniRef100 entry -
Xenopus tropicalis
Length = 417
Score = 33.1 bits (72), Expect = 7.8
Identities = 22/79 (27%), Positives = 38/79 (48%), Gaps = 2/79 (2%)
Frame = +3
Query: 66 NVSYSKLFNISSNLSI*CQSYY--NNPIYYYHTIP*RTKINKNHCPLICHPIPTKAPTNT 239
N +S ++ S + + C +YY N+ +YYH I N+C + H PT
Sbjct: 213 NCKHSNIYYFSIHNNCGCFNYYSSNHKHHYYHP-----HIIHNNCSINYHN-----PTYK 262
Query: 240 YSIYRNYQCQYL*IFCLTI 296
+ YR++ C++ I+C I
Sbjct: 263 HHYYRSHNCKHSNIYCFII 281
>UniRef50_Q2FAX4 Cluster: Rh2; n=2; Cercopithecine herpesvirus
8|Rep: Rh2 - Cercopithecine herpesvirus 8 (Rhesus
cytomegalovirus)
Length = 183
Score = 33.1 bits (72), Expect = 7.8
Identities = 21/57 (36%), Positives = 28/57 (49%)
Frame = -3
Query: 761 LSCEPSPIHCSLYYLLLHRTWRFCSLRIRKPEHSHTFEEPSSARHEDTPHS*TGRKP 591
L+C PSP L L H + L R P SHT +P + RH TP + + R+P
Sbjct: 12 LTCPPSPYSLPLLIYLRHTSTSCTHLSPRSP--SHTSTQPPTPRH--TPTTRSPRRP 64
>UniRef50_Q9WUP4 Cluster: SRD5A2L; n=24; Tetrapoda|Rep: SRD5A2L -
Mus musculus (Mouse)
Length = 330
Score = 33.1 bits (72), Expect = 7.8
Identities = 29/111 (26%), Positives = 42/111 (37%), Gaps = 2/111 (1%)
Frame = -1
Query: 715 YYIGLGGFVLCELGNLSIHILLKNLRPPGTKIRRIPKPDGNPFSLLLNFVSCPNYTYEFG 536
+ +G+ F H++L NLR K I PF +VS NY E
Sbjct: 215 HILGMVMFFWSSAHQYKCHVILSNLRR-NKKGVVIHCQHRIPFGDWFEYVSSANYLAELM 273
Query: 535 SWLFFTIMTKCAPAG--LFAAAGFYQMAVWAIGKHRNYKKEFPDYPKGRKA 389
++ + L F+ A+ A H+ Y+ F YPK RKA
Sbjct: 274 IYISMAVTFGLHNLTWWLVVTYVFFSQALSAFFNHKFYRSTFVSYPKHRKA 324
>UniRef50_Q4N2Y4 Cluster: Putative uncharacterized protein; n=1;
Theileria parva|Rep: Putative uncharacterized protein -
Theileria parva
Length = 101
Score = 33.1 bits (72), Expect = 7.8
Identities = 22/74 (29%), Positives = 32/74 (43%)
Frame = -1
Query: 763 AYHVNHPLYTAPCTTCYYIGLGGFVLCELGNLSIHILLKNLRPPGTKIRRIPKPDGNPFS 584
A+ VN+P AP C ++ + L H+ L LR + + P G PF
Sbjct: 10 AFAVNNPNNYAPIKFCVFLNMFAQGL----QFYCHVKLSKLRTDTSDAKVYKVPKGGPF- 64
Query: 583 LLLNFVSCPNYTYE 542
NF+ CP+Y E
Sbjct: 65 ---NFILCPHYLAE 75
>UniRef50_Q38944 Cluster: Probable steroid reductase DET2; n=13;
Eukaryota|Rep: Probable steroid reductase DET2 -
Arabidopsis thaliana (Mouse-ear cress)
Length = 262
Score = 33.1 bits (72), Expect = 7.8
Identities = 24/62 (38%), Positives = 30/62 (48%), Gaps = 2/62 (3%)
Frame = -1
Query: 568 VSCPNYTYEFGSWLFFTIMT-KCAPAGLFAAAGFYQMAVWAIGKHRNYKKEF-PDYPKGR 395
VSCPNY E WL + +MT A G F + A H+ Y +F +YPK R
Sbjct: 196 VSCPNYFGEAIEWLGWAVMTWSWAGIGFFLYT-CSNLFPRARASHKWYIAKFKEEYPKTR 254
Query: 394 KA 389
KA
Sbjct: 255 KA 256
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 769,002,106
Number of Sequences: 1657284
Number of extensions: 16988239
Number of successful extensions: 40489
Number of sequences better than 10.0: 56
Number of HSP's better than 10.0 without gapping: 38829
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 40445
length of database: 575,637,011
effective HSP length: 99
effective length of database: 411,565,895
effective search space used: 63792713725
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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