Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P09_pT_F13
(847 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q1HPY0 Cluster: Zinc-containing alcohol dehydrogenase; ... 597 e-169
UniRef50_Q4PP82 Cluster: Putative zinc-containing alcohol dehydr... 286 4e-76
UniRef50_UPI000051A87A Cluster: PREDICTED: similar to R04B5.5; n... 285 7e-76
UniRef50_UPI00015B5FCF Cluster: PREDICTED: similar to putative z... 283 5e-75
UniRef50_A7SKJ4 Cluster: Predicted protein; n=1; Nematostella ve... 235 1e-60
UniRef50_A7RKY5 Cluster: Predicted protein; n=1; Nematostella ve... 226 6e-58
UniRef50_A4FHA7 Cluster: Zinc-binding dehydrogenase; n=1; Saccha... 163 4e-39
UniRef50_A3EXU4 Cluster: Zinc-containing alcohol dehydrogenase-l... 161 3e-38
UniRef50_A0UVK1 Cluster: Alcohol dehydrogenase, zinc-binding; n=... 144 3e-33
UniRef50_Q2AGV2 Cluster: Zinc-containing alcohol dehydrogenase s... 138 1e-31
UniRef50_A4XHJ7 Cluster: Alcohol dehydrogenase GroES domain prot... 135 1e-30
UniRef50_UPI000038E1A4 Cluster: hypothetical protein Faci_030008... 134 3e-30
UniRef50_Q98CF7 Cluster: 2,3-butanediol dehydrogenase; n=5; Rhiz... 130 3e-29
UniRef50_A7EYS9 Cluster: Putative uncharacterized protein; n=1; ... 127 4e-28
UniRef50_Q9WYD4 Cluster: Alcohol dehydrogenase, zinc-containing;... 125 1e-27
UniRef50_Q8UB54 Cluster: Zinc-binding dehydrogenase; n=3; Rhizob... 124 2e-27
UniRef50_Q8KQG6 Cluster: Mannitol dehydrogenase; n=12; Bacteria|... 124 2e-27
UniRef50_Q829Q5 Cluster: Putative zinc-binding dehydrogenase; n=... 112 9e-24
UniRef50_Q3A2I8 Cluster: Putative zinc-containing alcohol dehydr... 111 2e-23
UniRef50_A1BBK6 Cluster: Alcohol dehydrogenase GroES domain prot... 111 2e-23
UniRef50_Q06004 Cluster: Sorbitol dehydrogenase; n=5; Bacillales... 111 3e-23
UniRef50_Q3IVK2 Cluster: Zinc-containing alcohol dehydrogenase; ... 108 1e-22
UniRef50_Q8ELI9 Cluster: Sorbitol dehydrogenase; n=2; Bacillacea... 107 5e-22
UniRef50_Q5KJK1 Cluster: Zinc-binding dehydrogenase, putative; n... 105 1e-21
UniRef50_Q4LED8 Cluster: Dehydrogenase; n=1; uncultured crenarch... 104 2e-21
UniRef50_Q81V29 Cluster: Alcohol dehydrogenase, zinc-containing;... 102 1e-20
UniRef50_A3JMN6 Cluster: Dehydrogenase; n=4; Bacteria|Rep: Dehyd... 101 2e-20
UniRef50_Q5V6U8 Cluster: Zinc-binding dehydrogenase; n=1; Haloar... 101 2e-20
UniRef50_Q92YT8 Cluster: Putative; n=2; Alphaproteobacteria|Rep:... 100 5e-20
UniRef50_P39400 Cluster: Uncharacterized zinc-type alcohol dehyd... 100 5e-20
UniRef50_Q38ZV8 Cluster: Zinc-containing alcohol dehydrogenase s... 99 7e-20
UniRef50_Q02912 Cluster: Sorbitol dehydrogenase; n=1; Bombyx mor... 100 9e-20
UniRef50_A6VRA2 Cluster: Alcohol dehydrogenase GroES domain prot... 99 1e-19
UniRef50_A5JSX4 Cluster: Zinc-containing alcohol dehydrogenase; ... 99 1e-19
UniRef50_A7II35 Cluster: Alcohol dehydrogenase GroES domain prot... 99 2e-19
UniRef50_A0JVZ3 Cluster: Alcohol dehydrogenase GroES domain prot... 98 3e-19
UniRef50_O97479 Cluster: CG1982-PA; n=17; Bilateria|Rep: CG1982-... 96 9e-19
UniRef50_A1CFY8 Cluster: Xylitol dehydrogenase; n=22; Ascomycota... 96 9e-19
UniRef50_UPI00015970BD Cluster: GutB1; n=1; Bacillus amyloliquef... 95 3e-18
UniRef50_Q7N973 Cluster: Similarities with different types of de... 95 3e-18
UniRef50_Q46N56 Cluster: Zinc-containing alcohol dehydrogenase s... 95 3e-18
UniRef50_A5FCD7 Cluster: Alcohol dehydrogenase, zinc-binding dom... 94 3e-18
UniRef50_A1HSQ8 Cluster: Alcohol dehydrogenase GroES domain prot... 94 3e-18
UniRef50_P36624 Cluster: Putative sorbitol dehydrogenase; n=1; S... 94 3e-18
UniRef50_A6BDE4 Cluster: Putative uncharacterized protein; n=2; ... 94 5e-18
UniRef50_A5D5N1 Cluster: Threonine dehydrogenase and related Zn-... 94 5e-18
UniRef50_Q3ACJ3 Cluster: Sorbitol dehydrogenase; n=1; Carboxydot... 93 8e-18
UniRef50_Q9K5Y6 Cluster: L-iditol 2-dehydrogenase; n=8; Bacteria... 93 1e-17
UniRef50_Q48FD6 Cluster: Oxidoreductase, zinc-binding; n=2; Pseu... 93 1e-17
UniRef50_A0TC93 Cluster: Alcohol dehydrogenase GroES-like; n=15;... 93 1e-17
UniRef50_Q9Z9U1 Cluster: Sorbitol dehydrogenase; n=14; Bacillale... 93 1e-17
UniRef50_Q12E06 Cluster: Alcohol dehydrogenase GroES-like; n=2; ... 92 2e-17
UniRef50_Q8R9L6 Cluster: Threonine dehydrogenase and related Zn-... 91 2e-17
UniRef50_Q8EMM7 Cluster: Dehydrogenase; n=1; Oceanobacillus ihey... 91 4e-17
UniRef50_Q1Q2R9 Cluster: Similar to sorbitol dehydrogenase; n=1;... 91 4e-17
UniRef50_A5D4M1 Cluster: Zn-dependent alcohol dehydrogenases; n=... 91 4e-17
UniRef50_A3H8A1 Cluster: Alcohol dehydrogenase GroES-like; n=1; ... 91 4e-17
UniRef50_Q44P31 Cluster: Zinc-containing alcohol dehydrogenase s... 90 6e-17
UniRef50_A3DCE7 Cluster: Alcohol dehydrogenase GroES-like protei... 90 7e-17
UniRef50_A5D1M5 Cluster: Threonine dehydrogenase and related Zn-... 89 1e-16
UniRef50_Q4WT02 Cluster: Xylitol dehydrogenase; n=8; Pezizomycot... 89 1e-16
UniRef50_Q0TXS2 Cluster: Putative uncharacterized protein; n=2; ... 89 1e-16
UniRef50_UPI0000384B5E Cluster: COG1063: Threonine dehydrogenase... 89 2e-16
UniRef50_Q1ARQ8 Cluster: Alcohol dehydrogenase GroES-like protei... 89 2e-16
UniRef50_A3TNY9 Cluster: Zinc-binding dehydrogenase; n=5; Actino... 87 4e-16
UniRef50_Q0UDN4 Cluster: Putative uncharacterized protein; n=2; ... 87 4e-16
UniRef50_A3PQM0 Cluster: Alcohol dehydrogenase GroES domain prot... 87 5e-16
UniRef50_A0NKD6 Cluster: Zc-binding dehydrogenase; n=3; Oenococc... 87 5e-16
UniRef50_Q5V6V7 Cluster: Zinc-binding dehydrogenase; n=1; Haloar... 87 5e-16
UniRef50_Q16R00 Cluster: Alcohol dehydrogenase; n=3; Culicidae|R... 87 7e-16
UniRef50_Q8ZJN2 Cluster: L-threonine 3-dehydrogenase; n=41; Bact... 87 7e-16
UniRef50_A3I7D7 Cluster: Zinc-containing alcohol dehydrogenase, ... 86 9e-16
UniRef50_Q58D31 Cluster: Sorbitol dehydrogenase; n=8; Eukaryota|... 86 9e-16
UniRef50_Q67XB8 Cluster: Sorbitol dehydrogenase-like protein; n=... 85 2e-15
UniRef50_Q98GG6 Cluster: L-iditol 2-dehydrogenase; n=5; Alphapro... 85 3e-15
UniRef50_P77280 Cluster: Uncharacterized zinc-type alcohol dehyd... 85 3e-15
UniRef50_Q8EL78 Cluster: Alcohol dehydrogenase; n=1; Oceanobacil... 84 4e-15
UniRef50_Q65L02 Cluster: Putative uncharacterized protein; n=1; ... 84 4e-15
UniRef50_Q5BBC2 Cluster: Putative uncharacterized protein; n=1; ... 84 4e-15
UniRef50_A3Q0B6 Cluster: Alcohol dehydrogenase GroES domain prot... 84 5e-15
UniRef50_A3DI68 Cluster: Alcohol dehydrogenase GroES-like protei... 83 6e-15
UniRef50_A1UPQ2 Cluster: Alcohol dehydrogenase GroES domain prot... 83 6e-15
UniRef50_A1R5Y9 Cluster: L-threonine 3-dehydrogenase; n=1; Arthr... 83 6e-15
UniRef50_A0V2V8 Cluster: Alcohol dehydrogenase GroES-like; n=1; ... 83 6e-15
UniRef50_A0IRE9 Cluster: Alcohol dehydrogenase GroES-like; n=1; ... 83 6e-15
UniRef50_Q0FV22 Cluster: Sorbitol dehydrogenase; n=1; Roseovariu... 83 9e-15
UniRef50_Q5WJ77 Cluster: Sorbitol dehydrogenase; n=1; Bacillus c... 83 1e-14
UniRef50_Q5LVU9 Cluster: Sorbitol dehydrogenase, putative; n=13;... 83 1e-14
UniRef50_A7F503 Cluster: Putative uncharacterized protein; n=1; ... 83 1e-14
UniRef50_A7DRK1 Cluster: Alcohol dehydrogenase GroES domain prot... 83 1e-14
UniRef50_P0A9S4 Cluster: Galactitol-1-phosphate 5-dehydrogenase;... 83 1e-14
UniRef50_Q2KCX6 Cluster: Probable zinc-type alcohol dehydrogenas... 82 1e-14
UniRef50_A6M074 Cluster: Alcohol dehydrogenase GroES domain prot... 82 1e-14
UniRef50_Q9RTU4 Cluster: L-threonine 3-dehydrogenase; n=178; Bac... 82 1e-14
UniRef50_Q9KGB7 Cluster: Sorbitol dehydrogenase; n=28; Bacillale... 82 2e-14
UniRef50_Q00796 Cluster: Sorbitol dehydrogenase; n=35; Eumetazoa... 82 2e-14
UniRef50_A5I7E3 Cluster: Sorbitol dehydrogenase; n=7; Clostridiu... 81 3e-14
UniRef50_A0GHL5 Cluster: Alcohol dehydrogenase GroES-like; n=1; ... 81 3e-14
UniRef50_O58389 Cluster: Probable L-threonine 3-dehydrogenase; n... 81 3e-14
UniRef50_O35045 Cluster: Zinc-containing alcohol dehydrogenase; ... 81 3e-14
UniRef50_Q5KPJ4 Cluster: Sorbitol dehydrogenase, putative; n=1; ... 81 3e-14
UniRef50_Q3B3S5 Cluster: Alcohol dehydrogenase, zinc-containing;... 81 5e-14
UniRef50_Q0TT56 Cluster: L-iditol 2-dehydrogenase; n=3; Clostrid... 81 5e-14
UniRef50_Q65L05 Cluster: YjmD; n=1; Bacillus licheniformis ATCC ... 80 8e-14
UniRef50_Q3WCL0 Cluster: Zinc-containing alcohol dehydrogenase s... 80 8e-14
UniRef50_Q1QWS0 Cluster: Alcohol dehydrogenase GroES-like protei... 80 8e-14
UniRef50_Q8DK96 Cluster: Tll0970 protein; n=6; Cyanobacteria|Rep... 79 1e-13
UniRef50_Q2G759 Cluster: GroES-related; n=1; Novosphingobium aro... 79 1e-13
UniRef50_A0JVX4 Cluster: Alcohol dehydrogenase GroES domain prot... 79 2e-13
UniRef50_A0JVW4 Cluster: Alcohol dehydrogenase GroES domain prot... 79 2e-13
UniRef50_Q57517 Cluster: Uncharacterized zinc-type alcohol dehyd... 79 2e-13
UniRef50_Q89F70 Cluster: L-idonate 5-dehydrogenase; n=1; Bradyrh... 78 2e-13
UniRef50_Q2RG84 Cluster: Alcohol dehydrogenase superfamily, zinc... 78 2e-13
UniRef50_Q188T6 Cluster: Putative sugar-phosphate dehydrogenase;... 78 3e-13
UniRef50_A3U1C0 Cluster: Threonine 3-dehydrogenase; n=1; Oceanic... 78 3e-13
UniRef50_A0QS68 Cluster: 2-deoxy-scyllo-inosamine dehydrogenase;... 78 3e-13
UniRef50_O28179 Cluster: Alcohol dehydrogenase, zinc-dependent; ... 78 3e-13
UniRef50_Q1AZ51 Cluster: Alcohol dehydrogenase GroES-like protei... 77 4e-13
UniRef50_A0UVE8 Cluster: Alcohol dehydrogenase GroES-like; n=1; ... 77 4e-13
UniRef50_Q1IQV5 Cluster: Alcohol dehydrogenase, zinc-binding; n=... 77 6e-13
UniRef50_A1WT70 Cluster: Alcohol dehydrogenase, zinc-binding dom... 77 6e-13
UniRef50_P38105 Cluster: Starvation-sensing protein rspB; n=36; ... 77 6e-13
UniRef50_A1DK00 Cluster: Alcohol dehydrogenase; n=7; Pezizomycot... 69 6e-13
UniRef50_Q8DIZ5 Cluster: Sorbitol dehydrogenase; n=6; Cyanobacte... 77 7e-13
UniRef50_Q62AB8 Cluster: Oxidoreductase, zinc-binding dehydrogen... 77 7e-13
UniRef50_A4YDY9 Cluster: Alcohol dehydrogenase GroES domain prot... 77 7e-13
UniRef50_Q1J2J1 Cluster: Alcohol dehydrogenase GroES-like; n=1; ... 76 1e-12
UniRef50_A6TKR3 Cluster: Alcohol dehydrogenase, zinc-binding dom... 76 1e-12
UniRef50_Q7S9B3 Cluster: Putative uncharacterized protein NCU070... 76 1e-12
UniRef50_Q1AVM7 Cluster: Alcohol dehydrogenase GroES-like protei... 76 1e-12
UniRef50_Q5HLF5 Cluster: Sorbitol dehydrogenase, putative; n=10;... 75 2e-12
UniRef50_A6LBP5 Cluster: Putative uncharacterized protein; n=1; ... 75 2e-12
UniRef50_A1D0R7 Cluster: Alcohol dehydrogenase; n=2; Trichocomac... 75 2e-12
UniRef50_A0LL41 Cluster: Alcohol dehydrogenase GroES domain prot... 75 2e-12
UniRef50_A6X6E2 Cluster: Alcohol dehydrogenase GroES domain prot... 75 3e-12
UniRef50_Q2U8M8 Cluster: Threonine dehydrogenase and related Zn-... 75 3e-12
UniRef50_Q8R7K0 Cluster: L-threonine 3-dehydrogenase; n=3; cellu... 75 3e-12
UniRef50_Q8ELG9 Cluster: Sorbitol dehydrogenase; n=2; Bacillacea... 74 4e-12
UniRef50_Q72U55 Cluster: Zinc binding dehydrogenase; n=4; Leptos... 74 4e-12
UniRef50_Q6AAC4 Cluster: Alcohol dehydrogenase; n=1; Propionibac... 74 4e-12
UniRef50_Q3WAW5 Cluster: Zinc-containing alcohol dehydrogenase s... 74 4e-12
UniRef50_Q5K981 Cluster: L-iditol 2-dehydrogenase, putative; n=6... 74 5e-12
UniRef50_Q6MJG4 Cluster: Putative alcohol dehydrogenase I; n=1; ... 73 7e-12
UniRef50_Q01PH7 Cluster: Alcohol dehydrogenase GroES domain prot... 73 7e-12
UniRef50_A4AMR5 Cluster: Zn-dependent alcohol dehydrogenase; n=2... 73 7e-12
UniRef50_A1SFU6 Cluster: Alcohol dehydrogenase, zinc-binding dom... 73 7e-12
UniRef50_Q97VB8 Cluster: Alcohol dehydrogenase; n=1; Sulfolobus ... 73 7e-12
UniRef50_UPI000050F926 Cluster: COG1063: Threonine dehydrogenase... 73 9e-12
UniRef50_Q8YNV3 Cluster: All4458 protein; n=7; Bacteria|Rep: All... 73 9e-12
UniRef50_A4FFG8 Cluster: Probable alcohol dehydrogenase; n=1; Sa... 73 9e-12
UniRef50_Q4LED7 Cluster: Sorbitol dehydrogenase; n=1; uncultured... 73 9e-12
UniRef50_Q39TG2 Cluster: Alcohol dehydrogenase superfamily, zinc... 73 1e-11
UniRef50_Q59715 Cluster: Benzyl alcohol dehydrogenase II; n=5; P... 73 1e-11
UniRef50_Q3W5D6 Cluster: Zinc-containing alcohol dehydrogenase s... 73 1e-11
UniRef50_Q01VI1 Cluster: Alcohol dehydrogenase GroES domain prot... 73 1e-11
UniRef50_A5V1N3 Cluster: Alcohol dehydrogenase GroES domain prot... 73 1e-11
UniRef50_A4XIU4 Cluster: Alcohol dehydrogenase GroES domain prot... 73 1e-11
UniRef50_A0QTC9 Cluster: 2-deoxy-scyllo-inosamine dehydrogenase;... 73 1e-11
UniRef50_A0LRZ3 Cluster: Alcohol dehydrogenase GroES domain prot... 73 1e-11
UniRef50_Q5KAN3 Cluster: Xylitol dehydrogenase, putative; n=1; F... 73 1e-11
UniRef50_Q9S270 Cluster: Putative zinc-binding alcohol dehydroge... 72 2e-11
UniRef50_Q025V7 Cluster: Alcohol dehydrogenase GroES domain prot... 72 2e-11
UniRef50_Q4WT03 Cluster: L-arabinitol 4-dehydrogenase; n=5; Tric... 72 2e-11
UniRef50_P22144 Cluster: D-xylulose reductase; n=8; Saccharomyce... 72 2e-11
UniRef50_Q3MCP8 Cluster: Zinc-containing alcohol dehydrogenase s... 72 2e-11
UniRef50_Q39JN7 Cluster: Zinc-containing alcohol dehydrogenase s... 72 2e-11
UniRef50_Q0RW76 Cluster: Probable Zn-containing alcohol dehydrog... 72 2e-11
UniRef50_Q7QAQ4 Cluster: ENSANGP00000011378; n=3; Culicidae|Rep:... 72 2e-11
UniRef50_Q0U204 Cluster: Putative uncharacterized protein; n=1; ... 72 2e-11
UniRef50_P39713 Cluster: Zinc-type alcohol dehydrogenase-like pr... 72 2e-11
UniRef50_Q1PZD2 Cluster: Strong similarity to L-threonine dehydr... 71 3e-11
UniRef50_A1UQB9 Cluster: Alcohol dehydrogenase GroES domain prot... 71 3e-11
UniRef50_A6VLA0 Cluster: Alcohol dehydrogenase GroES domain prot... 71 4e-11
UniRef50_A0LGB6 Cluster: Alcohol dehydrogenase GroES domain prot... 71 4e-11
UniRef50_A3H9A2 Cluster: Alcohol dehydrogenase GroES-like; n=1; ... 71 4e-11
UniRef50_Q89GJ2 Cluster: Bll6353 protein; n=2; Proteobacteria|Re... 71 5e-11
UniRef50_Q0RXH7 Cluster: Alcohol dehydrogenase; n=1; Rhodococcus... 71 5e-11
UniRef50_A0QWX1 Cluster: Oxidoreductase, zinc-binding dehydrogen... 71 5e-11
UniRef50_Q0UEG3 Cluster: Putative uncharacterized protein; n=1; ... 71 5e-11
UniRef50_Q4PHJ5 Cluster: Putative uncharacterized protein; n=1; ... 70 6e-11
UniRef50_A3DME0 Cluster: Alcohol dehydrogenase GroES domain prot... 70 6e-11
UniRef50_Q62K93 Cluster: Oxidoreductase, zinc-binding dehydrogen... 70 8e-11
UniRef50_Q7CVQ9 Cluster: AGR_L_281p; n=7; Alphaproteobacteria|Re... 70 8e-11
UniRef50_A1SCW8 Cluster: Alcohol dehydrogenase, zinc-binding dom... 70 8e-11
UniRef50_Q8ES57 Cluster: NADP-dependent alcohol dehydrogenase; n... 69 1e-10
UniRef50_Q8KKS7 Cluster: Putative L-iditol 2-dehydrogenase prote... 69 1e-10
UniRef50_A5G4J1 Cluster: Alcohol dehydrogenase GroES domain prot... 69 1e-10
UniRef50_A3S6P0 Cluster: L-threonine 3-dehydrogenase; n=2; Bacte... 69 1e-10
UniRef50_A3Q0B4 Cluster: Alcohol dehydrogenase GroES domain prot... 69 1e-10
UniRef50_A1WNS6 Cluster: Alcohol dehydrogenase GroES domain prot... 69 1e-10
UniRef50_A3GIE9 Cluster: Sorbitol dehydrogenase; n=2; Saccharomy... 69 1e-10
UniRef50_A0V2V9 Cluster: Alcohol dehydrogenase GroES-like; n=1; ... 69 2e-10
UniRef50_A1CNK3 Cluster: Xylitol dehydrogenase XdhB, putative; n... 69 2e-10
UniRef50_Q8ZUP0 Cluster: Alcohol dehydrogenase; n=2; Pyrobaculum... 69 2e-10
UniRef50_A3MWI2 Cluster: Alcohol dehydrogenase GroES domain prot... 69 2e-10
UniRef50_Q6L743 Cluster: 2-deoxy-scyllo-inosamine dehydrogenase;... 69 2e-10
UniRef50_Q701X1 Cluster: Putative zinc dependent alcohol dehydro... 68 3e-10
UniRef50_P77539 Cluster: Uncharacterized zinc-type alcohol dehyd... 68 3e-10
UniRef50_A6X5V4 Cluster: Alcohol dehydrogenase zinc-binding doma... 68 3e-10
UniRef50_Q0UBF8 Cluster: Putative uncharacterized protein; n=1; ... 68 3e-10
UniRef50_A0RV95 Cluster: L-iditol 2-dehydrogenase/threonine dehy... 68 3e-10
UniRef50_A2UF68 Cluster: Alcohol dehydrogenase GroES domain prot... 67 5e-10
UniRef50_A2R610 Cluster: Catalytic activity:; n=5; Trichocomacea... 67 5e-10
UniRef50_Q89IR8 Cluster: Bll5566 protein; n=2; Rhizobiales|Rep: ... 67 6e-10
UniRef50_Q1IJN0 Cluster: Alcohol dehydrogenase GroES-like; n=1; ... 67 6e-10
UniRef50_A1UG38 Cluster: Alcohol dehydrogenase GroES domain prot... 67 6e-10
UniRef50_A7RSK1 Cluster: Predicted protein; n=1; Nematostella ve... 67 6e-10
UniRef50_Q97WA1 Cluster: Alcohol dehydrogenase; n=9; cellular or... 67 6e-10
UniRef50_UPI0000E46CC1 Cluster: PREDICTED: similar to SORD prote... 66 8e-10
UniRef50_Q1NX30 Cluster: Zinc-containing alcohol dehydrogenase s... 66 8e-10
UniRef50_A7C3H6 Cluster: Zinc-containing alcohol dehydrogenase s... 66 8e-10
UniRef50_A5ZM46 Cluster: Putative uncharacterized protein; n=2; ... 66 8e-10
UniRef50_Q5KPZ2 Cluster: Sorbitol dehydrogenase, putative; n=1; ... 66 8e-10
UniRef50_Q97BK9 Cluster: Alcohol dehydrogenase [ADH]; n=3; Therm... 66 8e-10
UniRef50_Q5WC08 Cluster: Galactitol-1-phosphate 5-dehydrogenase;... 66 1e-09
UniRef50_A4QH16 Cluster: Putative uncharacterized protein; n=1; ... 66 1e-09
UniRef50_A4J9K3 Cluster: Alcohol dehydrogenase GroES domain prot... 66 1e-09
UniRef50_Q0S6W9 Cluster: Zn-binding dehydrogenase; n=4; Actinomy... 66 1e-09
UniRef50_A0JXR0 Cluster: Alcohol dehydrogenase, zinc-binding dom... 66 1e-09
UniRef50_Q976Y8 Cluster: 344aa long hypothetical alcohol dehydro... 66 1e-09
UniRef50_Q930C9 Cluster: IdnD L-idonate 5-dehydrogenase; n=4; Al... 65 2e-09
UniRef50_Q3ZWK2 Cluster: Alcohol dehydrogenase, zinc-containing;... 65 2e-09
UniRef50_Q1INA4 Cluster: Alcohol dehydrogenase, zinc-binding; n=... 65 2e-09
UniRef50_Q2U7Y6 Cluster: Zn-dependent alcohol dehydrogenases; n=... 65 2e-09
UniRef50_Q5LQR4 Cluster: L-idonate 5-dehydrogenase; n=13; Alphap... 65 2e-09
UniRef50_Q70KF0 Cluster: 2-deoxy-scyllo-inosamine dehydrogenase;... 65 2e-09
UniRef50_A4GII5 Cluster: Sorbitol dehydrogenase; n=3; environmen... 64 3e-09
UniRef50_A1X3A2 Cluster: Putative Zn-dependent dehydrogenase; n=... 64 3e-09
UniRef50_Q8ZU64 Cluster: Alcohol dehydrogenase; n=5; Thermoprote... 64 3e-09
UniRef50_Q67N85 Cluster: L-threonine 3-dehydrogenase; n=10; Bact... 64 3e-09
UniRef50_Q83GG5 Cluster: Zinc-type alcohol dehydrogenase; n=3; A... 64 4e-09
UniRef50_Q565X2 Cluster: 6-hydroxycylohex-1-ene-1-carboxyl-CoA d... 64 4e-09
UniRef50_A1DBH5 Cluster: Alcohol dehydrogenase; n=3; Pezizomycot... 64 4e-09
UniRef50_Q9ZEX7 Cluster: Dehydrogenase; n=1; Thiobacillus sp.|Re... 64 6e-09
UniRef50_A6W9X6 Cluster: Alcohol dehydrogenase GroES domain prot... 64 6e-09
UniRef50_Q0LJ45 Cluster: Alcohol dehydrogenase GroES-like; n=1; ... 63 7e-09
UniRef50_A5V071 Cluster: Alcohol dehydrogenase GroES domain prot... 63 7e-09
UniRef50_A1SI74 Cluster: Alcohol dehydrogenase, zinc-binding dom... 63 7e-09
UniRef50_Q2UHR2 Cluster: Sorbitol dehydrogenase; n=8; Ascomycota... 63 7e-09
UniRef50_Q9KBH6 Cluster: BH1951 protein; n=1; Bacillus haloduran... 62 2e-08
UniRef50_Q987C5 Cluster: Alcohol dehydrogenase; n=4; Rhizobiales... 62 2e-08
UniRef50_Q8Z6Z4 Cluster: Starvation sensing protein RspB; n=1; S... 62 2e-08
UniRef50_Q2LQ73 Cluster: Zinc-binding dehydrogenase; n=2; Bacter... 62 2e-08
UniRef50_Q0RVL1 Cluster: Zn-dependent alcohol dehydrogenase; n=1... 62 2e-08
UniRef50_A0V7I1 Cluster: Alcohol dehydrogenase GroES-like; n=2; ... 62 2e-08
UniRef50_Q07786 Cluster: Sorbitol dehydrogenase 2; n=8; Saccharo... 62 2e-08
UniRef50_P39346 Cluster: L-idonate 5-dehydrogenase; n=17; Gammap... 62 2e-08
UniRef50_UPI00015BC9A2 Cluster: UPI00015BC9A2 related cluster; n... 61 3e-08
UniRef50_Q89Z65 Cluster: Putative zinc-type alcohol dehydrogenas... 61 3e-08
UniRef50_A3PJU5 Cluster: Alcohol dehydrogenase GroES domain prot... 61 3e-08
UniRef50_Q4PCL3 Cluster: Putative uncharacterized protein; n=1; ... 61 3e-08
UniRef50_Q02972 Cluster: Probable mannitol dehydrogenase 2; n=12... 61 3e-08
UniRef50_Q6AA39 Cluster: Zinc-binding dehydrogenase; n=1; Propio... 61 4e-08
UniRef50_Q97VW0 Cluster: Alcohol dehydrogenase; n=7; Thermoprote... 61 4e-08
UniRef50_Q97TZ4 Cluster: Sorbitol dehydrogenase; n=4; Sulfolobac... 61 4e-08
UniRef50_A7BC76 Cluster: Putative uncharacterized protein; n=1; ... 60 5e-08
UniRef50_Q8A1P2 Cluster: Sorbitol dehydrogenase; n=4; Bacteroide... 60 7e-08
UniRef50_A4AED3 Cluster: Alcohol dehydrogenase; n=1; marine acti... 60 7e-08
UniRef50_A1BBU7 Cluster: Alcohol dehydrogenase, zinc-binding dom... 60 7e-08
UniRef50_P77360 Cluster: Uncharacterized zinc-type alcohol dehyd... 60 7e-08
UniRef50_UPI0000553E21 Cluster: Zinc-containing alcohol dehydrog... 60 9e-08
UniRef50_Q7UT38 Cluster: Zinc-type alcohol dehydrogenase; n=1; P... 60 9e-08
UniRef50_Q7U377 Cluster: Putative Zinc-binding dehydrogenase; n=... 60 9e-08
UniRef50_Q11C06 Cluster: Alcohol dehydrogenase GroES-like; n=1; ... 60 9e-08
UniRef50_A5V2Z1 Cluster: Alcohol dehydrogenase, zinc-binding dom... 60 9e-08
UniRef50_A3PW48 Cluster: Alcohol dehydrogenase GroES domain prot... 60 9e-08
UniRef50_Q6BC32 Cluster: Glycerol dehydrogenase; n=3; Saccharomy... 60 9e-08
UniRef50_Q9HJX2 Cluster: Alcohol dehydrogenase related protein; ... 60 9e-08
UniRef50_Q8KCJ7 Cluster: 2-desacetyl-2-hydroxyethyl bacteriochlo... 59 1e-07
UniRef50_A6CDR3 Cluster: Alcohol dehydrogenase, zinc-containing;... 59 1e-07
UniRef50_A5N5N6 Cluster: Zn-dependent dehydrogenase; n=1; Clostr... 59 1e-07
UniRef50_A0JVZ1 Cluster: Alcohol dehydrogenase GroES domain prot... 59 1e-07
UniRef50_Q6L0S1 Cluster: Zinc-binding alcohol dehydrogenase; n=1... 59 1e-07
UniRef50_Q73RL3 Cluster: Sorbitol dehydrogenase, putative; n=1; ... 59 2e-07
UniRef50_A1VP65 Cluster: Alcohol dehydrogenase, zinc-binding dom... 59 2e-07
UniRef50_A1SLI2 Cluster: Alcohol dehydrogenase GroES domain prot... 59 2e-07
UniRef50_Q97ZV3 Cluster: Alcohol dehydrogenase; n=7; Thermoprote... 59 2e-07
UniRef50_O67374 Cluster: Alcohol dehydrogenase; n=1; Aquifex aeo... 58 2e-07
UniRef50_Q0S5L3 Cluster: Alcohol dehydrogenase; n=1; Rhodococcus... 58 2e-07
UniRef50_Q0UBV8 Cluster: Putative uncharacterized protein; n=2; ... 58 2e-07
UniRef50_A0RXG2 Cluster: Zn-dependent alcohol dehydrogenase; n=2... 58 2e-07
UniRef50_UPI000023E4F0 Cluster: hypothetical protein FG07506.1; ... 58 3e-07
UniRef50_A7M5E0 Cluster: Putative uncharacterized protein; n=1; ... 58 3e-07
UniRef50_A6LDY7 Cluster: Putative zinc-type alcohol dehydrogenas... 58 3e-07
UniRef50_A5FZ32 Cluster: Alcohol dehydrogenase GroES domain prot... 58 3e-07
UniRef50_A5CZI6 Cluster: Threonine dehydrogenase and related Zn-... 58 3e-07
UniRef50_Q8ZW83 Cluster: Alcohol dehydrogenase; n=4; Pyrobaculum... 58 3e-07
UniRef50_Q98D10 Cluster: Putative D-xylulose reductase; n=9; cel... 58 3e-07
UniRef50_Q63FG9 Cluster: Zinc-containing alcohol dehydrogenase; ... 58 4e-07
UniRef50_Q5SK85 Cluster: Zinc-dependent dehydrogenase; n=2; Ther... 57 5e-07
UniRef50_Q84H90 Cluster: 6-hydroxyhexanoate dehydrogenase; n=3; ... 57 5e-07
UniRef50_Q00SV0 Cluster: COG1064: Zn-dependent alcohol dehydroge... 57 5e-07
UniRef50_Q6NDJ8 Cluster: Putative Zn-binding dehydrogenase; n=1;... 57 6e-07
UniRef50_Q848J9 Cluster: Zinc-type alcohol dehydrogenase; n=1; u... 57 6e-07
UniRef50_Q9VDQ9 Cluster: CG4836-PC, isoform C; n=4; Eukaryota|Re... 57 6e-07
UniRef50_Q62CY1 Cluster: Alcohol dehydrogenase, zinc-containing;... 56 8e-07
UniRef50_Q5KJG0 Cluster: Xylitol dehydrogenase, putative; n=1; F... 56 8e-07
UniRef50_A1RYE2 Cluster: Alcohol dehydrogenase GroES domain prot... 56 8e-07
UniRef50_Q6PGX2 Cluster: Zgc:63674; n=2; Danio rerio|Rep: Zgc:63... 56 1e-06
UniRef50_Q97NH4 Cluster: Alcohol dehydrogenase, zinc-containing;... 56 1e-06
UniRef50_Q0RZT6 Cluster: Probable alcohol dehydrogenase; n=2; Rh... 56 1e-06
UniRef50_A7HEW5 Cluster: Alcohol dehydrogenase GroES domain prot... 56 1e-06
UniRef50_A6W685 Cluster: Alcohol dehydrogenase zinc-binding doma... 56 1e-06
UniRef50_Q5V607 Cluster: Zinc-binding dehydrogenase; n=5; Haloba... 56 1e-06
UniRef50_P09347 Cluster: 5-exo-alcohol dehydrogenase; n=4; Prote... 56 1e-06
UniRef50_Q1A676 Cluster: Alcohol dehydrogenase; n=4; Bacteria|Re... 56 1e-06
UniRef50_Q028K3 Cluster: Alcohol dehydrogenase GroES domain prot... 56 1e-06
UniRef50_A3GHR6 Cluster: Alcohol dehydrogenase, class V; n=3; Pi... 56 1e-06
UniRef50_A6EYW6 Cluster: Zinc-containing alcohol dehydrogenase s... 55 2e-06
UniRef50_A1CFL1 Cluster: Alcohol dehydrogenase; n=5; Dikarya|Rep... 55 2e-06
UniRef50_Q5V2C1 Cluster: Alcohol dehydrogenase; n=3; Halobacteri... 55 2e-06
UniRef50_Q8ZVD9 Cluster: Alcohol dehydrogenase; n=3; Pyrobaculum... 55 3e-06
UniRef50_A0JVV9 Cluster: Alcohol dehydrogenase GroES domain prot... 54 3e-06
UniRef50_Q5BFT1 Cluster: Putative uncharacterized protein; n=1; ... 54 3e-06
UniRef50_A4FD94 Cluster: Alcohol dehydrogenase GroES-like protei... 54 5e-06
UniRef50_Q89MU1 Cluster: Bll4101 protein; n=9; Bradyrhizobiaceae... 54 6e-06
UniRef50_Q5KRB2 Cluster: Putative benzyl alcohol dehydrogenase; ... 54 6e-06
UniRef50_A0QZF0 Cluster: Oxidoreductase, zinc-binding dehydrogen... 54 6e-06
UniRef50_Q5YTW6 Cluster: Putative dehydrogenase; n=3; Actinomyce... 53 8e-06
UniRef50_Q5SL93 Cluster: Zinc-binding dehydrogenase; n=2; Thermu... 53 8e-06
UniRef50_Q46NN2 Cluster: Zinc-containing alcohol dehydrogenase s... 53 8e-06
UniRef50_Q11Z80 Cluster: Alcohol dehydrogenase, zinc-binding; n=... 53 8e-06
UniRef50_Q0RVY2 Cluster: Dehydrogenase; n=1; Rhodococcus sp. RHA... 53 8e-06
UniRef50_A1ICC4 Cluster: Putative uncharacterized protein; n=1; ... 53 8e-06
UniRef50_Q6BTK7 Cluster: Similar to sp|Q04894 Saccharomyces cere... 53 8e-06
UniRef50_Q5A958 Cluster: Potential secondary alcohol dehydrogena... 53 8e-06
UniRef50_Q9HIM3 Cluster: Alcohol dehydrogenase related protein; ... 53 8e-06
UniRef50_P0A4X1 Cluster: NADP-dependent alcohol dehydrogenase C;... 53 8e-06
UniRef50_Q767G1 Cluster: Putative dehydrogenase; n=1; Actinoplan... 53 1e-05
UniRef50_A3LUA4 Cluster: Secondary alcohol dehydrogenase; n=9; S... 53 1e-05
UniRef50_A2QFZ8 Cluster: Catalytic activity: alcohol dehydrogena... 53 1e-05
UniRef50_UPI00006CBCAE Cluster: oxidoreductase, zinc-binding deh... 52 1e-05
UniRef50_UPI00005F10EF Cluster: COG1063: Threonine dehydrogenase... 52 1e-05
UniRef50_Q8NTT0 Cluster: Zn-dependent alcohol dehydrogenases; n=... 52 1e-05
UniRef50_A6NT70 Cluster: Putative uncharacterized protein; n=1; ... 52 1e-05
UniRef50_A0ADQ4 Cluster: Putative dehydrogenase; n=1; Streptomyc... 52 1e-05
UniRef50_Q4WY60 Cluster: Oxidoreductase, zinc-binding; n=13; Asc... 52 1e-05
UniRef50_A1CN58 Cluster: Pyruvate decarboxylase; n=2; Aspergillu... 52 1e-05
UniRef50_Q5UX28 Cluster: Alcohol dehydrogenase; n=1; Haloarcula ... 52 1e-05
UniRef50_Q18IV0 Cluster: NADPH:quinone reductase; n=1; Haloquadr... 52 2e-05
UniRef50_P48523 Cluster: Cinnamyl-alcohol dehydrogenase; n=110; ... 52 2e-05
UniRef50_Q7NR39 Cluster: Probable glutathione-dependent aldehyde... 52 2e-05
UniRef50_Q72KK6 Cluster: Quinone oxidoreductase; n=4; cellular o... 52 2e-05
UniRef50_A5V690 Cluster: Alcohol dehydrogenase GroES domain prot... 52 2e-05
UniRef50_A4AQN2 Cluster: Putative zinc-binding dehydrogenase; n=... 52 2e-05
UniRef50_A0DCB5 Cluster: Chromosome undetermined scaffold_45, wh... 52 2e-05
UniRef50_Q4P5Y2 Cluster: Putative uncharacterized protein; n=1; ... 52 2e-05
UniRef50_Q01NE8 Cluster: Alcohol dehydrogenase GroES domain prot... 51 3e-05
UniRef50_A7HFA6 Cluster: Alcohol dehydrogenase GroES domain prot... 51 3e-05
UniRef50_A6LR91 Cluster: Alcohol dehydrogenase GroES domain prot... 51 3e-05
UniRef50_A4FJI0 Cluster: Putative zinc-binding alcohol dehydroge... 51 3e-05
UniRef50_A4FB48 Cluster: Putative uncharacterized protein; n=1; ... 51 3e-05
UniRef50_Q4JB77 Cluster: NAD-dependent alcohol dehydrogenase; n=... 51 3e-05
UniRef50_Q0LSY1 Cluster: Alcohol dehydrogenase, zinc-binding:Alc... 51 4e-05
UniRef50_Q93QG4 Cluster: 6-hydroxyhexanoate dehydrogenase; n=1; ... 50 6e-05
UniRef50_A4XGJ9 Cluster: Alcohol dehydrogenase, zinc-binding dom... 50 6e-05
UniRef50_A1UI23 Cluster: Alcohol dehydrogenase GroES domain prot... 50 6e-05
UniRef50_A1K6Y3 Cluster: Putative alcohol dehydrogenase; n=1; Az... 50 6e-05
UniRef50_Q830W4 Cluster: Alcohol dehydrogenase, zinc-containing;... 50 7e-05
UniRef50_Q1LNT3 Cluster: Alcohol dehydrogenase GroES-like protei... 50 7e-05
UniRef50_Q6BC30 Cluster: Dihydroxyacetone reductase; n=11; cellu... 50 7e-05
UniRef50_A1C7T1 Cluster: Alcohol dehydrogenase, zinc-containing;... 50 7e-05
UniRef50_Q6W1X8 Cluster: Alcohol dehydrogenase; n=1; Rhizobium s... 50 1e-04
UniRef50_Q1J6P8 Cluster: Zn-dependent alcohol dehydrogenase; n=1... 50 1e-04
UniRef50_Q0S7E4 Cluster: Possible alcohol dehydrogenase; n=2; No... 50 1e-04
UniRef50_A4QVF8 Cluster: Zinc-binding dehydrogenase; n=4; Pezizo... 50 1e-04
UniRef50_Q89RJ2 Cluster: Blr2780 protein; n=10; Proteobacteria|R... 49 1e-04
UniRef50_A3P9N6 Cluster: Oxidoreductase, zinc-binding dehydrogen... 49 1e-04
UniRef50_A5AB83 Cluster: Contig An08c0230, complete genome; n=9;... 49 1e-04
UniRef50_A6T0C4 Cluster: Oxidoreductase; n=1; Janthinobacterium ... 49 2e-04
UniRef50_Q0CK29 Cluster: Putative uncharacterized protein; n=2; ... 49 2e-04
UniRef50_A7DNK0 Cluster: Alcohol dehydrogenase GroES domain prot... 49 2e-04
UniRef50_Q7US13 Cluster: Probable zinc-type alcohol dehydrogenas... 48 2e-04
UniRef50_A0PM90 Cluster: Short-chain dehydrogenase Adh_1; n=3; M... 48 2e-04
UniRef50_Q2V3G2 Cluster: Uncharacterized protein At4g21580.2; n=... 48 2e-04
UniRef50_A1CC26 Cluster: Alcohol dehydrogenase; n=4; cellular or... 48 2e-04
UniRef50_UPI0000DD8301 Cluster: PREDICTED: similar to Sorbitol d... 48 3e-04
UniRef50_Q88TA9 Cluster: Oxidoreductase; n=1; Lactobacillus plan... 48 3e-04
UniRef50_Q1LBS2 Cluster: Alcohol dehydrogenase GroES-like protei... 48 3e-04
UniRef50_A5IYL7 Cluster: Alcohol dehydrogenase; n=2; Mycoplasma ... 48 3e-04
UniRef50_A0R5Y8 Cluster: Quinone oxidoreductase; n=4; Bacteria|R... 48 3e-04
UniRef50_Q4KE06 Cluster: D-isomer specific 2-hydroxyacid dehydro... 48 4e-04
UniRef50_Q39MG8 Cluster: Zinc-containing alcohol dehydrogenase s... 48 4e-04
UniRef50_A1SJ83 Cluster: Alcohol dehydrogenase GroES domain prot... 48 4e-04
UniRef50_A4QUV6 Cluster: Putative uncharacterized protein; n=2; ... 48 4e-04
UniRef50_Q9YBP2 Cluster: Putative alcohol dehydrogenase; n=1; Ae... 48 4e-04
UniRef50_Q72S01 Cluster: Alcohol dehydrogenase; n=2; Leptospira ... 47 5e-04
UniRef50_A0QXS6 Cluster: Oxidoreductase; n=1; Mycobacterium smeg... 47 5e-04
UniRef50_A0CEE0 Cluster: Chromosome undetermined scaffold_171, w... 47 5e-04
UniRef50_Q1DLA7 Cluster: Alcohol dehydrogenase; n=2; Eurotiomyce... 47 5e-04
UniRef50_A2QBA8 Cluster: Catalytic activity: an alcohol + NAD(+)... 47 5e-04
UniRef50_Q89ZF3 Cluster: Sorbitol dehydrogenase; n=1; Bacteroide... 47 7e-04
UniRef50_Q3Y1X5 Cluster: Zinc-containing alcohol dehydrogenase s... 47 7e-04
UniRef50_A1W5R7 Cluster: Alcohol dehydrogenase GroES domain prot... 47 7e-04
UniRef50_Q8EVN7 Cluster: NADP-dependent alcohol dehydrogenase; n... 46 0.001
UniRef50_A7CUZ3 Cluster: Alcohol dehydrogenase zinc-binding doma... 46 0.001
UniRef50_A4FD89 Cluster: Alcohol dehydrogenase, zinc-binding; n=... 46 0.001
UniRef50_A2QAN5 Cluster: Catalytic activity: Alcohol + NAD+ = Al... 46 0.001
UniRef50_Q6KZL8 Cluster: Alcohol dehydrogenase; n=1; Picrophilus... 46 0.001
UniRef50_UPI000038CBA0 Cluster: COG0604: NADPH:quinone reductase... 46 0.001
UniRef50_UPI000023CF80 Cluster: hypothetical protein FG00231.1; ... 46 0.001
UniRef50_Q38VW5 Cluster: Putative zinc-containing alcohol dehydr... 46 0.001
UniRef50_Q1LBX2 Cluster: Alcohol dehydrogenase, zinc-binding; n=... 46 0.001
UniRef50_A7HAS7 Cluster: Alcohol dehydrogenase GroES domain prot... 46 0.001
UniRef50_A0NL69 Cluster: Sorbitol dehydrogenase; n=2; Oenococcus... 46 0.001
UniRef50_A0KRX9 Cluster: Alcohol dehydrogenase, zinc-binding dom... 46 0.001
UniRef50_Q4P2L9 Cluster: Putative uncharacterized protein; n=1; ... 46 0.001
UniRef50_Q5V676 Cluster: Alcohol dehydrogenase; n=7; cellular or... 46 0.001
UniRef50_Q6ACG5 Cluster: Alcohol dehydrogenase; n=1; Leifsonia x... 46 0.002
UniRef50_Q24T43 Cluster: Putative uncharacterized protein; n=1; ... 46 0.002
UniRef50_Q1YQ87 Cluster: Zinc-containing alcohol dehydrogenase f... 46 0.002
UniRef50_A5FC99 Cluster: Alcohol dehydrogenase GroES domain prot... 46 0.002
UniRef50_A0JRS4 Cluster: Alcohol dehydrogenase GroES domain prot... 46 0.002
UniRef50_Q0CIG6 Cluster: Putative uncharacterized protein; n=1; ... 46 0.002
UniRef50_P27250 Cluster: Uncharacterized zinc-type alcohol dehyd... 46 0.002
UniRef50_Q826L9 Cluster: Putative dehydrogenase; n=2; Actinomyce... 45 0.002
UniRef50_Q7NCG2 Cluster: Gll3017 protein; n=3; Cyanobacteria|Rep... 45 0.002
UniRef50_Q0RIJ3 Cluster: Putative Zn-dependent alcohol dehydroge... 45 0.002
UniRef50_A6WBJ8 Cluster: Alcohol dehydrogenase GroES domain prot... 45 0.002
UniRef50_A4XEZ1 Cluster: Alcohol dehydrogenase, zinc-binding dom... 45 0.002
UniRef50_A3YE39 Cluster: Oxidoreductase, zinc-binding; n=2; Prot... 45 0.002
UniRef50_Q86AP0 Cluster: Similar to Ralstonia solanacearum (Pseu... 45 0.002
UniRef50_Q59KU9 Cluster: Potential butanediol dehydrogenase; n=3... 45 0.002
UniRef50_A1DJM6 Cluster: Alcohol dehydrogenase, putative; n=1; N... 45 0.002
UniRef50_Q8Y8W9 Cluster: Lmo0773 protein; n=17; Bacillales|Rep: ... 45 0.003
UniRef50_Q5YR32 Cluster: Putative dehydrogenase; n=1; Nocardia f... 45 0.003
UniRef50_Q2BQK7 Cluster: Putative zinc-binding oxidoreductase; n... 45 0.003
UniRef50_A1SLY9 Cluster: Alcohol dehydrogenase GroES domain prot... 45 0.003
UniRef50_Q5CRI2 Cluster: Predicted mannitol dehydrogenase; zinc ... 45 0.003
UniRef50_A5HNZ8 Cluster: Zn-dependent alcohol dehydrogenase; n=2... 44 0.004
UniRef50_A0FZB5 Cluster: Alcohol dehydrogenase, zinc-binding; n=... 44 0.004
UniRef50_A7PKL2 Cluster: Chromosome chr7 scaffold_20, whole geno... 44 0.004
UniRef50_Q66UT6 Cluster: NAD-and Zn-dependent alcohol dehydrogen... 44 0.004
UniRef50_Q6N5I5 Cluster: Putative quinone oxidoreductase; n=1; R... 44 0.005
UniRef50_Q0RUZ2 Cluster: Probable Zn-dependent oxidoreductase; n... 44 0.005
UniRef50_A3EVY2 Cluster: NADPH quinone reductase; n=1; Leptospir... 44 0.005
UniRef50_Q9HTE3 Cluster: Glutathione-independent formaldehyde de... 44 0.005
UniRef50_Q96XE0 Cluster: NAD-dependent alcohol dehydrogenase; n=... 44 0.005
UniRef50_Q47Z05 Cluster: Oxidoreductase, zinc-binding; n=1; Colw... 44 0.006
UniRef50_Q7D7T9 Cluster: Zinc-binding dehydrogenase; n=15; Mycob... 44 0.006
UniRef50_Q11IR2 Cluster: Alcohol dehydrogenase, zinc-binding; n=... 44 0.006
UniRef50_A7H7K7 Cluster: Alcohol dehydrogenase zinc-binding doma... 44 0.006
UniRef50_Q207V9 Cluster: Mannitol dehydrogenase-like; n=3; Physa... 44 0.006
UniRef50_A0RZ53 Cluster: Zn-dependent oxidoreductase; n=4; Therm... 44 0.006
UniRef50_Q9A4J4 Cluster: Alcohol dehydrogenase, zinc-containing;... 43 0.008
UniRef50_Q60AS0 Cluster: Alcohol dehydrogenase, zinc-containing;... 43 0.008
UniRef50_Q1QUA2 Cluster: Alcohol dehydrogenase, zinc-binding; n=... 43 0.008
UniRef50_Q5NXJ4 Cluster: Predicted Zinc-containing alcohol dehyd... 43 0.011
UniRef50_Q08P53 Cluster: Alcohol dehydrogenase, zinc-dependent; ... 43 0.011
UniRef50_A0JVX5 Cluster: Alcohol dehydrogenase, zinc-binding dom... 43 0.011
UniRef50_A0HHZ1 Cluster: Alcohol dehydrogenase GroES-like; n=1; ... 43 0.011
UniRef50_O74822 Cluster: Mitochondrial peptidase; n=1; Schizosac... 43 0.011
UniRef50_Q4K7P8 Cluster: Oxidoreductase, zinc-binding; n=1; Pseu... 42 0.015
UniRef50_Q83YE5 Cluster: Shy5; n=3; Actinomycetales|Rep: Shy5 - ... 42 0.015
UniRef50_Q3Y1Y0 Cluster: Zinc-containing alcohol dehydrogenase s... 42 0.015
UniRef50_Q1DFR9 Cluster: Oxidoreductase, zinc-binding dehydrogen... 42 0.015
UniRef50_A6RPM4 Cluster: Putative uncharacterized protein; n=1; ... 42 0.015
UniRef50_A1DFN2 Cluster: Alcohol dehydrogenase; n=1; Neosartorya... 42 0.015
UniRef50_A3MVR8 Cluster: Alcohol dehydrogenase GroES domain prot... 42 0.015
UniRef50_Q9S247 Cluster: Putative alcohol dehydrogenase; n=4; Ac... 42 0.019
UniRef50_Q9KUG9 Cluster: Quinone oxidoreductase; n=30; Vibrional... 42 0.019
UniRef50_Q2W5C7 Cluster: Zn-dependent alcohol dehydrogenase; n=6... 42 0.019
UniRef50_O51103 Cluster: Cell division protein, putative; n=3; B... 42 0.019
UniRef50_A1UD06 Cluster: Alcohol dehydrogenase GroES domain prot... 42 0.019
UniRef50_A0H1E5 Cluster: Alcohol dehydrogenase, zinc-binding; n=... 42 0.019
UniRef50_Q5AY17 Cluster: Putative uncharacterized protein; n=1; ... 42 0.019
UniRef50_Q0U6M3 Cluster: Putative uncharacterized protein; n=1; ... 42 0.019
UniRef50_UPI000023EF5E Cluster: hypothetical protein FG11570.1; ... 42 0.026
UniRef50_Q81RD6 Cluster: Quinone oxidoreductase; n=14; Bacillus|... 42 0.026
UniRef50_Q8KUV8 Cluster: PANL16; n=2; Synechococcus elongatus PC... 42 0.026
UniRef50_Q21GE4 Cluster: Alcohol dehydrogenase GroES-like protei... 42 0.026
UniRef50_Q08VU5 Cluster: Putative uncharacterized protein; n=1; ... 42 0.026
UniRef50_A6UFW2 Cluster: Alcohol dehydrogenase zinc-binding doma... 42 0.026
UniRef50_A0IUR9 Cluster: Alcohol dehydrogenase, zinc-binding; n=... 42 0.026
UniRef50_Q0CLH2 Cluster: Putative uncharacterized protein; n=1; ... 42 0.026
UniRef50_Q5L161 Cluster: NADPH:quinone oxidoreductase; n=4; Bact... 41 0.034
UniRef50_Q39HW1 Cluster: Zinc-containing alcohol dehydrogenase s... 41 0.034
UniRef50_Q3XWD6 Cluster: Zinc-containing alcohol dehydrogenase s... 41 0.034
UniRef50_A3THV2 Cluster: Putative zinc-binding oxidoreductase; n... 41 0.034
UniRef50_A0R799 Cluster: Alcohol dehydrogenase; n=3; Bacteria|Re... 41 0.034
UniRef50_A0FSJ0 Cluster: Alcohol dehydrogenase, zinc-binding; n=... 41 0.034
UniRef50_A0RUX6 Cluster: Zn-dependent alcohol dehydrogenase; n=1... 41 0.034
UniRef50_Q9RZE4 Cluster: Alcohol dehydrogenase, zinc-containing;... 41 0.045
UniRef50_Q9RS48 Cluster: Alcohol dehydrogenase, zinc-containing;... 41 0.045
UniRef50_Q11E73 Cluster: Alcohol dehydrogenase, zinc-binding; n=... 41 0.045
UniRef50_A3GG69 Cluster: Alcohol dehydrogenase, class III, bacte... 41 0.045
UniRef50_UPI00015BB28C Cluster: Alcohol dehydrogenase, zinc-bind... 40 0.059
UniRef50_UPI0000E87C7F Cluster: predicted alcohol dehydrogenase,... 40 0.059
UniRef50_Q41EM7 Cluster: Zinc-containing alcohol dehydrogenase s... 40 0.059
UniRef50_Q3WG24 Cluster: Zinc-containing alcohol dehydrogenase s... 40 0.059
UniRef50_Q0SJ82 Cluster: Possible alcohol dehydrogenase; n=13; c... 40 0.059
UniRef50_A6GS72 Cluster: Probable zinc-binding dehydrogenase; n=... 40 0.059
UniRef50_A3SJT5 Cluster: Alcohol dehydrogenase, zinc-containing ... 40 0.059
UniRef50_A3Q6Z6 Cluster: Alcohol dehydrogenase, zinc-binding dom... 40 0.059
UniRef50_A1SHA7 Cluster: Dehydrogenase precursor; n=14; Bacteria... 40 0.059
UniRef50_A7F361 Cluster: Putative uncharacterized protein; n=1; ... 40 0.059
UniRef50_Q39HJ6 Cluster: Zinc-containing alcohol dehydrogenase s... 40 0.079
UniRef50_A5FWT0 Cluster: Alcohol dehydrogenase GroES domain prot... 40 0.079
UniRef50_A7R0K5 Cluster: Chromosome undetermined scaffold_311, w... 40 0.079
UniRef50_A4RX70 Cluster: Predicted protein; n=2; Ostreococcus|Re... 40 0.079
>UniRef50_Q1HPY0 Cluster: Zinc-containing alcohol dehydrogenase;
n=1; Bombyx mori|Rep: Zinc-containing alcohol
dehydrogenase - Bombyx mori (Silk moth)
Length = 342
Score = 597 bits (1473), Expect = e-169
Identities = 276/279 (98%), Positives = 277/279 (99%)
Frame = -1
Query: 847 EFSGTITDVGKKSVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGGW 668
EFSGTITDVGKKSVFR GQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGGW
Sbjct: 64 EFSGTITDVGKKSVFRKGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGGW 123
Query: 667 AQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNLW 488
AQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNLW
Sbjct: 124 AQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNLW 183
Query: 487 VTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLVTPDVLEKEKQLYDVIIDCTGVGKVM 308
VTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLVTPDVL+KEKQLYDVIIDCTGVGKVM
Sbjct: 184 VTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLVTPDVLDKEKQLYDVIIDCTGVGKVM 243
Query: 307 EISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIGVKINPFSFPNALGWLKAMG 128
EISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIGVKINPFSFPNALGWLKAMG
Sbjct: 244 EISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIGVKINPFSFPNALGWLKAMG 303
Query: 127 NRYVNYEKLGVKTYALSEYESALKDLRAGLVXKAMFKIN 11
NRYVNYEKLGVKTYALSEYESALKDLRAGLV KAMFKIN
Sbjct: 304 NRYVNYEKLGVKTYALSEYESALKDLRAGLVSKAMFKIN 342
>UniRef50_Q4PP82 Cluster: Putative zinc-containing alcohol
dehydrogenase; n=4; Endopterygota|Rep: Putative
zinc-containing alcohol dehydrogenase - Lysiphlebus
testaceipes (Greenbugs aphid parastoid)
Length = 340
Score = 286 bits (702), Expect = 4e-76
Identities = 134/279 (48%), Positives = 183/279 (65%), Gaps = 2/279 (0%)
Frame = -1
Query: 847 EFSGTITDVGK-KSVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
EFSG I D+G F+ GQ V +DPN C+ CDFC GKY +C GIN+T+GI+RDGG
Sbjct: 62 EFSGVIEDIGSIVKGFKIGQSVAIDPNSGCNKCDFCHTGKYHFCDNGGINNTIGIFRDGG 121
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
W+ + VP+ QVYLLP GV Q L EP SC+AHG+D +P+ VG IL++G+GIIG L
Sbjct: 122 WSTHAVVPESQVYLLPSGVEMPQAALAEPLSCLAHGWDIINPVTVGTNILVIGSGIIGLL 181
Query: 490 WVTSLHQLGHR-DVTVSEMNKVRLEIVNKLETGYRLVTPDVLEKEKQLYDVIIDCTGVGK 314
W LH G R VT+SE + R E V KL+ Y + +P L+ +K +D+ IDC+G G
Sbjct: 182 WACLLHLHGSRKTVTISEPIEARREAVKKLDLDYEINSPVQLKDKK--FDLAIDCSGSGP 239
Query: 313 VMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIGVKINPFSFPNALGWLKA 134
ME + L+ GG+ +FG P +I+PF IY KELTI+GV INPF+FP L ++A
Sbjct: 240 AMEAAVPLLKRGGRLCVFGVANPKATLTISPFDIYMKELTILGVNINPFTFPKGLALVRA 299
Query: 133 MGNRYVNYEKLGVKTYALSEYESALKDLRAGLVXKAMFK 17
M +Y+ ++ LG+K Y LSEY+ A + L+ G++ KA+FK
Sbjct: 300 MSKQYLIFDNLGIKVYKLSEYKDAFEALKKGVISKAIFK 338
>UniRef50_UPI000051A87A Cluster: PREDICTED: similar to R04B5.5; n=1;
Apis mellifera|Rep: PREDICTED: similar to R04B5.5 - Apis
mellifera
Length = 338
Score = 285 bits (700), Expect = 7e-76
Identities = 131/280 (46%), Positives = 187/280 (66%), Gaps = 2/280 (0%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
EF+GT+ +G F+ GQ+V VDPN C+ C++C G YQ+C GINST+GI++DGG
Sbjct: 62 EFAGTVDAIGSSVKNFKVGQRVAVDPNSGCNTCNYCHDGSYQHCSAGGINSTIGIYKDGG 121
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
++ + VP+ QVYL+PD V Q L EP SC+AHG+ + + + VG +L++GAGIIG L
Sbjct: 122 FSTHAIVPESQVYLIPDDVELHQAVLVEPLSCLAHGWKKLNSVNVGSNVLVIGAGIIGLL 181
Query: 490 WVTSLHQLG-HRDVTVSEMNKVRLEIVNKLETGYRLVTPDVLEKEKQLYDVIIDCTGVGK 314
W LH G + VT+SE + R ++V KL+ + +P+ L K YDV++DC+G
Sbjct: 182 WACMLHLHGLRKSVTISEPQEKRRKLVTKLDLDFEAKSPEQL---KNSYDVVVDCSGSAP 238
Query: 313 VMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIGVKINPFSFPNALGWLKA 134
+E S L GG+ +FG P + SI PFQ+Y KELTI+GV INPFSFP LG L+A
Sbjct: 239 AIEASIPLLAPGGRLCIFGVANPKAKFSIEPFQVYLKELTILGVNINPFSFPRGLGLLRA 298
Query: 133 MGNRYVNYEKLGVKTYALSEYESALKDLRAGLVXKAMFKI 14
M +RY+NY+KLG+K ++LS+Y AL+ L+ G + KA+FK+
Sbjct: 299 MADRYLNYDKLGIKVFSLSQYREALEALKRGEISKAVFKL 338
>UniRef50_UPI00015B5FCF Cluster: PREDICTED: similar to putative
zinc-containing alcohol dehydrogenase; n=1; Nasonia
vitripennis|Rep: PREDICTED: similar to putative
zinc-containing alcohol dehydrogenase - Nasonia
vitripennis
Length = 339
Score = 283 bits (693), Expect = 5e-75
Identities = 134/280 (47%), Positives = 183/280 (65%), Gaps = 2/280 (0%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
EF GT+ VG F+ GQ+V VDPN CS+CD C G Y C+ G+NST+GI+R+GG
Sbjct: 62 EFCGTVEAVGVSVKNFKVGQRVTVDPNSGCSMCDDCHVGCYHLCVNGGVNSTIGIFRNGG 121
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
WA + VP+ QVY +P+GV EQ L EP SC+AHG+ R +P+ VG+K+L++GAGIIG L
Sbjct: 122 WATHCCVPEVQVYHVPEGVEMEQAALSEPLSCLAHGWKRMNPIHVGQKVLVLGAGIIGLL 181
Query: 490 WVTSLHQLG-HRDVTVSEMNKVRLEIVNKLETGYRLVTPDVLEKEKQLYDVIIDCTGVGK 314
W + LH G + VTVSE R E+ K+ Y++ +P L+ + YDVI+DC+G G
Sbjct: 182 WSSILHLHGLRKTVTVSEPQDKRKEMAKKMGLDYQVTSPAELKGNE--YDVIVDCSGSGP 239
Query: 313 VMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIGVKINPFSFPNALGWLKA 134
ME + L GG++ +FG P INP+++Y KELTI GV INPFSF +G LKA
Sbjct: 240 AMESAIPLLARGGRFCIFGVADPKVNIKINPYEMYKKELTIYGVNINPFSFSRGIGLLKA 299
Query: 133 MGNRYVNYEKLGVKTYALSEYESALKDLRAGLVXKAMFKI 14
M + Y+ Y+ LG+K + LSEY AL L+ G + KA+FK+
Sbjct: 300 MASSYLQYDNLGIKVFKLSEYNVALDALKNGTISKAVFKL 339
>UniRef50_A7SKJ4 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 348
Score = 235 bits (574), Expect = 1e-60
Identities = 120/288 (41%), Positives = 176/288 (61%), Gaps = 11/288 (3%)
Frame = -1
Query: 847 EFSGTITDVGKKSVFRN-GQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
+F G + ++G + G +VV++P +C +CDFC KG+ C G N+ +GI R+GG
Sbjct: 60 QFVGIVKEIGADVQHVSVGDRVVINPLTSCGICDFCLKGQPHLCKVEGKNTAIGIKRNGG 119
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
WAQ+ ++ V LP V+ EQ EP SC+ G+D PL ++LI GAG G L
Sbjct: 120 WAQFCRLSAKNVIPLPHQVTFEQALFSEPMSCILRGWDLLVPLQTDAEVLICGAGNSGLL 179
Query: 490 WVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLVTPDVLEKE----KQL------YDV 341
W + LH G+R+V +SE+ K R +I + L G++LVTPDVL E KQ +DV
Sbjct: 180 WASFLHFRGYREVVISEVLKGRQKIAHGLNFGFQLVTPDVLVSEARNAKQNDDQEWGFDV 239
Query: 340 IIDCTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIGVKINPFSF 161
++DCTG K E S +LR GG+ +LFG CP ASINP Q+ KEL II + N F+F
Sbjct: 240 VVDCTGDPKCFEQSLQWLRQGGRLLLFGTCPRNANASINPNQLLQKELKIISYQGNSFTF 299
Query: 160 PNALGWLKAMGNRYVNYEKLGVKTYALSEYESALKDLRAGLVXKAMFK 17
+ + L+ MGN Y+ +E+LGV+T+ L EY +A++ +R+G + KA+F+
Sbjct: 300 TSGIQVLQDMGNHYLAFERLGVRTFQLQEYMAAIETMRSGEISKAVFE 347
>UniRef50_A7RKY5 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 347
Score = 226 bits (552), Expect = 6e-58
Identities = 108/288 (37%), Positives = 176/288 (61%), Gaps = 12/288 (4%)
Frame = -1
Query: 847 EFSGTITDVGK--KSVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDG 674
EFSG ++DVG K+V G +VVV+PN +C+ C CR+G+ +C G S +G+W++G
Sbjct: 60 EFSGVVSDVGSDVKNV-SIGDRVVVNPNSSCNTCKACRRGQPHFCEKGGTGSAIGVWKNG 118
Query: 673 GWAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGN 494
GW QY +V ++++P VS +Q LCEP SCV HG D+ P KIL+ G G+ G
Sbjct: 119 GWTQYARVHAPNIHIVPPQVSLKQAALCEPISCVLHGLDKLHPAARDSKILVSGTGVTGL 178
Query: 493 LWVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLVTPDVL----------EKEKQLYD 344
LW+ LH G+R VTV E ++ + L G++++ PD + + +D
Sbjct: 179 LWMCILHFHGYRRVTVIEFSEQWRMLAMGLSLGFKILHPDTVHTDLVEATQSQNNTWGFD 238
Query: 343 VIIDCTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIGVKINPFS 164
VII+CTG+ +++ + +L +GGK ++FG + I+P++I KE+ I+G +NPFS
Sbjct: 239 VIIECTGLSVLVQSAIKWLGYGGKLLIFGSSAKDSEVKISPYEILHKEIQILGSSMNPFS 298
Query: 163 FPNALGWLKAMGNRYVNYEKLGVKTYALSEYESALKDLRAGLVXKAMF 20
F +++ ++ M + Y++YEKLG+ + L++Y++AL L+ G V KA+F
Sbjct: 299 FLHSVELVRDM-SEYLDYEKLGISVFKLTDYQAALTKLKQGSVLKAVF 345
>UniRef50_A4FHA7 Cluster: Zinc-binding dehydrogenase; n=1;
Saccharopolyspora erythraea NRRL 2338|Rep: Zinc-binding
dehydrogenase - Saccharopolyspora erythraea (strain NRRL
23338)
Length = 336
Score = 163 bits (397), Expect = 4e-39
Identities = 102/271 (37%), Positives = 149/271 (54%), Gaps = 2/271 (0%)
Frame = -1
Query: 847 EFSGTITDVGKKSV--FRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDG 674
EF+G + ++G ++ F G +V VDP+ C C CR G C A N+T G +G
Sbjct: 60 EFAGEVVELGSEAPGGFEIGDRVAVDPSLFCGYCTPCRSGHGNLC--ANWNAT-GDTVNG 116
Query: 673 GWAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGN 494
+A+YV VP Y +PD ++ EQG L EP SC HG R + GE+ L+VGAG +G
Sbjct: 117 AFAEYVSVPAATCYRMPDEMTWEQGALVEPVSCAVHGV-RQIGVEAGERFLVVGAGTMG- 174
Query: 493 LWVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLVTPDVLEKEKQLYDVIIDCTGVGK 314
L + L Q G VTV + N RL ++L G V DV E + + +D +DCTG
Sbjct: 175 LLMQQLLQRGGAHVTVVDRNTARLGRASRL--GAVAVAGDVAELDGERFDAAVDCTGAAP 232
Query: 313 VMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIGVKINPFSFPNALGWLKA 134
+E +F+ LR GG+ ++FG P + S++PF+IY+ E+TI+G S+ AL L A
Sbjct: 233 AIEAAFDSLRRGGRLLVFGVAPAEARVSLSPFRIYNDEITIVGSMAVLHSYGAALD-LVA 291
Query: 133 MGNRYVNYEKLGVKTYALSEYESALKDLRAG 41
G VN E+L L ++ AL+ +R+G
Sbjct: 292 SG--AVNTEELLTDRLTLEDFPKALELMRSG 320
>UniRef50_A3EXU4 Cluster: Zinc-containing alcohol dehydrogenase-like
protein; n=1; Maconellicoccus hirsutus|Rep:
Zinc-containing alcohol dehydrogenase-like protein -
Maconellicoccus hirsutus (hibiscus mealybug)
Length = 201
Score = 161 bits (390), Expect = 3e-38
Identities = 81/201 (40%), Positives = 121/201 (60%), Gaps = 3/201 (1%)
Frame = -1
Query: 607 EQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNLWVTSLHQLGHRDVTVSEMNKV 428
+Q LCEP SC+ H D+ L +G ILIVGAGIIG LW LH LGHR VTVSE N V
Sbjct: 1 DQALLCEPLSCIVHALDKLHDLDIGCDILIVGAGIIGLLWSCLLHVLGHRKVTVSEPNVV 60
Query: 427 RLEIVNKLETGYRLVT-PDVLEKEKQL-YDVIIDCTGVGKVMEISFNYLRHGGKYVLFGC 254
R ++++ GY+ + D+L + D+ IDC+G + M+ + + GG +++FG
Sbjct: 61 RRKLLSNAGLGYKCMPWEDILRENPNFKVDICIDCSGNIEAMQAAIPIINSGGTFLIFGV 120
Query: 253 CPPTHQASINPFQIYDKELTIIGVKIN-PFSFPNALGWLKAMGNRYVNYEKLGVKTYALS 77
PP INP+ ++ E++++GV IN P SF A+ +L+++ ++ K+G+KT+ L
Sbjct: 121 APPEKTLIINPYNLFFNEISVVGVNINTPNSFERAMFYLESLSKTHLIINKIGIKTFFLH 180
Query: 76 EYESALKDLRAGLVXKAMFKI 14
E+E AL+ R G K MF I
Sbjct: 181 EHEKALQAFRDGSFTKIMFTI 201
>UniRef50_A0UVK1 Cluster: Alcohol dehydrogenase, zinc-binding; n=1;
Clostridium cellulolyticum H10|Rep: Alcohol
dehydrogenase, zinc-binding - Clostridium cellulolyticum
H10
Length = 302
Score = 144 bits (348), Expect = 3e-33
Identities = 88/269 (32%), Positives = 145/269 (53%), Gaps = 3/269 (1%)
Frame = -1
Query: 838 GTITDVGKK-SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGGWAQ 662
G ITD+GKK + F+ GQ+V DPN C CD C++ + +C + VG+ R G +AQ
Sbjct: 28 GIITDIGKKVTKFKIGQRVAADPNIFCETCDACKENRQNFCSDMEV---VGVTRHGAFAQ 84
Query: 661 YVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNLWVT 482
Y+ VP+ V+ + G++ + + EP +CV +G ++A + +G +LI GAG IG +
Sbjct: 85 YLTVPERCVFDV-SGLTFTEASMVEPLACVVYGQEKAG-IPLGASVLIFGAGPIGLMHSQ 142
Query: 481 SLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLVTPDVLEKEKQL--YDVIIDCTGVGKVM 308
G VTV ++ + +L + KL + + + EK + ++V+IDCTGV KV+
Sbjct: 143 LAAINGAASVTVVDLFEDKLALAKKLGADHTYTSAE-FEKLGLVNSFEVVIDCTGVPKVI 201
Query: 307 EISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIGVKINPFSFPNALGWLKAMG 128
E Y++ G + FG CP Q +INP++++ +EL I G +F A+ + K+ G
Sbjct: 202 EGEIKYVKDSGTILFFGVCPDNSQITINPYEVFKRELKICGSFALKKTFGKAVAFAKS-G 260
Query: 127 NRYVNYEKLGVKTYALSEYESALKDLRAG 41
+N L K L + +D+ AG
Sbjct: 261 K--INLIDLVDKKLLLDDAPKLFEDIVAG 287
>UniRef50_Q2AGV2 Cluster: Zinc-containing alcohol dehydrogenase
superfamily; n=1; Halothermothrix orenii H 168|Rep:
Zinc-containing alcohol dehydrogenase superfamily -
Halothermothrix orenii H 168
Length = 336
Score = 138 bits (335), Expect = 1e-31
Identities = 89/271 (32%), Positives = 137/271 (50%), Gaps = 8/271 (2%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
E +G I + G++ + G KV +DPN C C +C +G+ C +G+ R+GG
Sbjct: 59 ENAGEIIETGRQVRSLKKGDKVCIDPNIFCGQCYYCHRGEVHLCKEL---QAIGVTRNGG 115
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
+A+Y+ P VY + + VS ++ L EP +C HG D A + G+ ++I+GAG IG +
Sbjct: 116 FAEYLVAPATNVYKVKENVSYKEMALVEPLACCLHGIDLAG-IRPGDFVVILGAGAIGLI 174
Query: 490 WVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLVTP--DVLEKEKQLY-----DVIID 332
+ G +V VSE N + ++ KL ++ P D LEKE ++ DV+I+
Sbjct: 175 LLQLALHSGASEVIVSEPNSKKRKLALKLGAS-KVFDPFNDNLEKEIKIIKREGADVVIE 233
Query: 331 CTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIGVKINPFSFPNA 152
G + S R GG +LFG P INPF+IY +EL + G INPF A
Sbjct: 234 AVGNIHTFKQSIQLARKGGSVLLFGVPPKDKVIEINPFEIYKRELKLKGAYINPFVTDRA 293
Query: 151 LGWLKAMGNRYVNYEKLGVKTYALSEYESAL 59
++ + + VN +KL Y L E + L
Sbjct: 294 ---VRILESGMVNLKKLVTSQYTLEELPNVL 321
>UniRef50_A4XHJ7 Cluster: Alcohol dehydrogenase GroES domain
protein; n=1; Caldicellulosiruptor saccharolyticus DSM
8903|Rep: Alcohol dehydrogenase GroES domain protein -
Caldicellulosiruptor saccharolyticus (strain ATCC 43494
/ DSM 8903)
Length = 324
Score = 135 bits (327), Expect = 1e-30
Identities = 80/265 (30%), Positives = 140/265 (52%)
Frame = -1
Query: 847 EFSGTITDVGKKSVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGGW 668
EF G + + K S+F+ G KV +DPN C +C FCR GK Q C + + +G+ +GG+
Sbjct: 62 EFCGEVVET-KSSLFKVGDKVSIDPNIYCGVCRFCRSGKVQLCESL---TALGVNLNGGF 117
Query: 667 AQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNLW 488
A+Y VP+ Q L D + E+ L EP +C HG + + +K+LI+G G IG +
Sbjct: 118 AEYAIVPEKQAILFED-IEFEEAALAEPLACCLHGIKKLEIKPI-DKVLIIGLGPIGLIM 175
Query: 487 VTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLVTPDVLEKEKQLYDVIIDCTGVGKVM 308
+ L G +V E+++ R EI ++ + + E + +D++I+C G + +
Sbjct: 176 LEILKLYGAYNVYGYEIDEFRKEIAK-----WQGIKGIIEENTDEKFDIVIECAGTKESI 230
Query: 307 EISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIGVKINPFSFPNALGWLKAMG 128
E++F L+ GG+ ++F P INPF+++ KE + +NPF+ A+ L+A
Sbjct: 231 EMAFEKLQKGGQLLVFSVPSPKTNVLINPFEMFKKEARVYWSFVNPFTQKLAIELLRA-- 288
Query: 127 NRYVNYEKLGVKTYALSEYESALKD 53
+ ++ + + +L E AL +
Sbjct: 289 -KKISLKHIITHKISLEELSQALNN 312
>UniRef50_UPI000038E1A4 Cluster: hypothetical protein Faci_03000847;
n=1; Ferroplasma acidarmanus fer1|Rep: hypothetical
protein Faci_03000847 - Ferroplasma acidarmanus fer1
Length = 333
Score = 134 bits (324), Expect = 3e-30
Identities = 79/245 (32%), Positives = 124/245 (50%), Gaps = 7/245 (2%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
EFSG IT +G+ F G +VVVDPN C C++C+ GK +C TVGI GG
Sbjct: 60 EFSGVITSIGEGVKSFMPGDRVVVDPNITCGQCEYCKGGKENFCENI---KTVGINYPGG 116
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
+ +YV VP+ VY +PD +S E + EP +C+ H +D L G I I G G IG
Sbjct: 117 YGEYVTVPEKVVYKIPDTMSFEAAAIVEPVACIIHAFDNTHVPLGGSAI-ISGTGFIGLA 175
Query: 490 WVTSLHQLGHRDVTVSEMNKVRLEIV-----NKLETGY-RLVTPDVLEKEKQLYDVIIDC 329
++ L +G+ V + N R + +K+ TG L+ D++ K +V+++
Sbjct: 176 FLQILKGMGYYPVYTMDTNPTRNLLAKKYGSDKIYTGIDDLMESDIIGKA----NVVVEA 231
Query: 328 TGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIGVKINPFSFPNAL 149
TG ++ + + GK F PP + I +IY KE++I G +NP++ A+
Sbjct: 232 TGSNSILSKTIDMASPSGKIFAFSVYPPGEKIEIESNKIYSKEISIFGDFVNPYTMRKAI 291
Query: 148 GWLKA 134
+ +
Sbjct: 292 NMISS 296
>UniRef50_Q98CF7 Cluster: 2,3-butanediol dehydrogenase; n=5;
Rhizobiales|Rep: 2,3-butanediol dehydrogenase -
Rhizobium loti (Mesorhizobium loti)
Length = 289
Score = 130 bits (315), Expect = 3e-29
Identities = 79/242 (32%), Positives = 118/242 (48%), Gaps = 10/242 (4%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
EFSG + +GK S F G +V DPN AC C C G+ C +N+ +GI RDGG
Sbjct: 6 EFSGIVEAIGKAVSGFAVGDRVTGDPNIACGRCPHCHAGRVNLC--RNLNA-IGIHRDGG 62
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
+A+YV +PQ Q ++LP + G CEP C HG D A + G ++++G G+IG L
Sbjct: 63 FAEYVVLPQKQAFILPADLPPTHGAFCEPLGCCLHGVDLAQ-IKPGSSVVVLGGGVIGLL 121
Query: 490 WVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRL--VTPDVLE----KEKQL---YDVI 338
V G + +S R + +L + DV++ E + DV+
Sbjct: 122 TVQLAKLAGATTIILSTRQASRRVLAEELGATATVDPTAGDVIDAIAGSEGLMPGGADVV 181
Query: 337 IDCTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIGVKINPFSFP 158
+C GV +E S R GG V+ G P +A PF + +EL ++G +NP++
Sbjct: 182 FECAGVRDTVEQSMRLARAGGTVVIVGVTPQGMKAEFEPFDLLFRELKVVGSFLNPYTHR 241
Query: 157 NA 152
A
Sbjct: 242 RA 243
>UniRef50_A7EYS9 Cluster: Putative uncharacterized protein; n=1;
Sclerotinia sclerotiorum 1980|Rep: Putative
uncharacterized protein - Sclerotinia sclerotiorum 1980
Length = 376
Score = 127 bits (306), Expect = 4e-28
Identities = 83/285 (29%), Positives = 145/285 (50%), Gaps = 11/285 (3%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
E G I G K F G +VV D + C C +CR+G+ C + G+ DGG
Sbjct: 95 ETVGVIAATGPKVKGFNVGDRVVADNSELCEECFYCRRGQLLLCENFNAH---GVTMDGG 151
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
+A+Y P +V+ + + +S L EP SC AHG ++ +P + G +L+ GAG G +
Sbjct: 152 FAEYCAYPAAKVFKI-ENLSDVDATLLEPASCAAHGLEKIAPKM-GSTVLMFGAGPTGLV 209
Query: 490 WVTSLHQLGHRDVTVSEMNKVRLEIVNKLETG--YRLVTPD--------VLEKEKQLYDV 341
L Q G V ++ +++E+ KL+ Y ++ D + ++ K +D+
Sbjct: 210 LAQLLRQNGGCKVVLAAPGGLKMELAKKLDAADIYIELSRDNPEAQFQKIKDEYKYGFDI 269
Query: 340 IIDCTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIGVKINPFSF 161
+++ TG K++E + NY+R GGK V++G + + + P +I+ E+TI+G + F
Sbjct: 270 VVEATGSAKILEDAINYVRRGGKLVVYGVYSSSARVTWPPSKIFGDEITILGSFSETYMF 329
Query: 160 PNALGWLKAMGNRYVNYEKLGVKTYALSEYESALKDLRAGLVXKA 26
P A+ +L + G V E + KT+ L ++ AL+ ++ KA
Sbjct: 330 PAAIDYLDS-GK--VKVEGIVNKTFKLEQWGEALESIKNKSAIKA 371
>UniRef50_Q9WYD4 Cluster: Alcohol dehydrogenase, zinc-containing;
n=2; Thermotoga|Rep: Alcohol dehydrogenase,
zinc-containing - Thermotoga maritima
Length = 317
Score = 125 bits (302), Expect = 1e-27
Identities = 87/264 (32%), Positives = 136/264 (51%), Gaps = 9/264 (3%)
Frame = -1
Query: 823 VGKKSVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGGWAQYVKVPQ 644
V + VF GQ VV+DPNR+C CD+CRKG Q+C + +T G+ GG+A+YV V
Sbjct: 64 VERSGVFEKGQMVVIDPNRSCGKCDYCRKGMSQFC--ENLQAT-GVTEPGGFAEYVLVEN 120
Query: 643 DQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNLWVTSLHQL- 467
QVY + + V E+ EP SCV G ++IL+VGAG IG ++ ++
Sbjct: 121 SQVYPVRN-VPAERAVFAEPLSCVLEGVKMVKHGFY-DRILVVGAGSIGVIFGLIFKKIF 178
Query: 466 GHRDVTVSEMNKVRLEIVNKLETGYRLVTPDVLEKEKQLYDVIIDCTGVGKVMEISFNYL 287
++ ++E ++ R E V + G ++ P K YD+ ++C+G + + F +
Sbjct: 179 PGAEIVLAEKDEKRAEYVVQ-TFGLKVDEP------KGEYDLTVECSGTVEGFKTCFEHT 231
Query: 286 RHGGKYVLFGCCPPTHQASINPFQIYDKELTIIGVKINPFSFPNALGWLKAMGNRYVNYE 107
GG + F I+PF+IY KE+ I+G +NPF+ A +K + + +E
Sbjct: 232 GKGGMLLQFSVISKDKMVEISPFEIYRKEMKILGSYLNPFTMKEA---VKIIESGEFPFE 288
Query: 106 KL--------GVKTYALSEYESAL 59
KL GVK Y LS ++ AL
Sbjct: 289 KLVTDRLDLEGVKEY-LSSHKKAL 311
>UniRef50_Q8UB54 Cluster: Zinc-binding dehydrogenase; n=3;
Rhizobiales|Rep: Zinc-binding dehydrogenase -
Agrobacterium tumefaciens (strain C58 / ATCC 33970)
Length = 338
Score = 124 bits (300), Expect = 2e-27
Identities = 75/244 (30%), Positives = 120/244 (49%), Gaps = 4/244 (1%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
E++G + V +VF+ G +VVVDPN C C CRKG C T G+ +GG
Sbjct: 62 EYAGEVAAVASDVTVFKAGDRVVVDPNLPCGTCASCRKGLTNLCSTL---KAYGVSHNGG 118
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRAS---PLLVGEKILIVGAGII 500
+A++ V D ++ + + L EP +CV +G A +V E L+ GAG I
Sbjct: 119 FAEFSVVRADHLHGI-GSMPYHVAALAEPLACVVNGMQSAGIGESGVVPENALVFGAGPI 177
Query: 499 GNLWVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLVTPDVLEKEKQLYDVIIDCTGV 320
G L SL G VT++++N+ RL L + + L ++++ +D + D TG+
Sbjct: 178 GLLLALSLKSRGIATVTMADINESRLAFAQDLGLQTAVSGSEALSRQRKEFDFVADATGI 237
Query: 319 GKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIGVKINPFSFPNALGWL 140
V E + GG + FG C P + S+ PF+I+ ++L ++G + P AL L
Sbjct: 238 APVAEAMIPLVADGGTALFFGVCAPDARISVAPFEIFRRQLKLVGSHSLNRNIPQALAIL 297
Query: 139 KAMG 128
+ G
Sbjct: 298 ETDG 301
>UniRef50_Q8KQG6 Cluster: Mannitol dehydrogenase; n=12;
Bacteria|Rep: Mannitol dehydrogenase - Leuconostoc
mesenteroides
Length = 338
Score = 124 bits (300), Expect = 2e-27
Identities = 83/283 (29%), Positives = 139/283 (49%), Gaps = 5/283 (1%)
Frame = -1
Query: 847 EFSGTITDVGKKSV-FRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
E SG + ++G + G +V VDPN C C +CR + + C S VG+ RDGG
Sbjct: 62 ENSGVVAEIGSAVTNVKVGDRVTVDPNIYCGQCKYCRTARPELCENL---SAVGVTRDGG 118
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
+ ++ P VY +PD VS + + EP SC HG + +K L++G G +G L
Sbjct: 119 FEEFFTAPASVVYPIPDNVSLKSAAVVEPISCAVHGIQLLK-VTPYQKALVIGDGFMGEL 177
Query: 490 WVTSLHQLGHRDVTVSEMNKVRLEIVNKLETG----YRLVTPDVLEKEKQLYDVIIDCTG 323
+V L G V ++ + +L + NK + G Y + D + + + YDVII+ G
Sbjct: 178 FVQILQAYGIHQVDLAGIVDEKLAM-NKEKFGVKNTYNTMKGDKIPEGE--YDVIIEAVG 234
Query: 322 VGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIGVKINPFSFPNALGW 143
+ + E + G + ++FG P + +N ++++ K+LTI G INP +F ++L
Sbjct: 235 LPQTQEAAIEASARGAQVLMFGVGGPDAKFQMNTYEVFQKQLTIQGSFINPNAFEDSLAL 294
Query: 142 LKAMGNRYVNYEKLGVKTYALSEYESALKDLRAGLVXKAMFKI 14
L + G +N E L + + + G+V KA+ K+
Sbjct: 295 LSS-GK--LNVEALMSHELDYKTVDDFVNG-KLGVVSKAVVKV 333
>UniRef50_Q829Q5 Cluster: Putative zinc-binding dehydrogenase; n=2;
Streptomyces|Rep: Putative zinc-binding dehydrogenase -
Streptomyces avermitilis
Length = 329
Score = 112 bits (270), Expect = 9e-24
Identities = 68/233 (29%), Positives = 110/233 (47%), Gaps = 1/233 (0%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
EF+G + +G + + G +V VDP+ C C +CR G C + +G+ GG
Sbjct: 59 EFAGEVVGLGTQVTEVSVGDRVAVDPSLYCYECRYCRTGHNNLCERW---AAIGVTTAGG 115
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
A+Y P LP+ V T+ L EP SC GYD L G +L+ G+G +G +
Sbjct: 116 AARYAVAPVANCVKLPEHVRTQDAALIEPLSCAVRGYDVLRSRL-GAHVLVYGSGTMGLM 174
Query: 490 WVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLVTPDVLEKEKQLYDVIIDCTGVGKV 311
+ + G V V ++N RL +L D L++ Q +DV++D TG
Sbjct: 175 MLELAKRTGAASVDVVDVNPARLTTARQLGVSGSAANADELDRP-QGWDVVVDATGNAAA 233
Query: 310 MEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIGVKINPFSFPNA 152
++ + G ++ FG + +I+P++IY++E+TI G SF A
Sbjct: 234 IQDGLGRVAKAGTFLQFGVADYATRVTIDPYRIYNQEITITGSMAVLHSFERA 286
>UniRef50_Q3A2I8 Cluster: Putative zinc-containing alcohol
dehydrogenase; n=1; Pelobacter carbinolicus DSM
2380|Rep: Putative zinc-containing alcohol dehydrogenase
- Pelobacter carbinolicus (strain DSM 2380 / Gra Bd 1)
Length = 327
Score = 111 bits (268), Expect = 2e-23
Identities = 71/234 (30%), Positives = 113/234 (48%), Gaps = 1/234 (0%)
Frame = -1
Query: 847 EFSGTITDVGKKSVFRN-GQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
E GTI ++G+ + GQ+V + PN C +C C+ G C + +GI +G
Sbjct: 59 EAIGTIVELGEGVTNVSVGQRVTIQPNFGCGVCPLCKSGHDNICPS---KIRLGIDTNGV 115
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
A+YV P V+ LP + E EP + HG + P +++L++GAGI+G L
Sbjct: 116 LAEYVTAPSRYVWALPADLPDEVAVFTEPLAVAVHGVNMLPPNK-DDRVLVMGAGIVG-L 173
Query: 490 WVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLVTPDVLEKEKQLYDVIIDCTGVGKV 311
+ ++ ++T ++ + RL++ KL L D L+ +DVI D +G
Sbjct: 174 LALQVARISGAEITACDLEQTRLDLAEKLGASRTLGERDALDAFHNTFDVIYDTSGSPAA 233
Query: 310 MEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIGVKINPFSFPNAL 149
E++ GGK V+F P+ +AS+N I KEL I G I FP A+
Sbjct: 234 FELALQLAAPGGKIVIFSL--PSQEASLNIQTIVRKELQIKGSMIYTDEFPQAI 285
>UniRef50_A1BBK6 Cluster: Alcohol dehydrogenase GroES domain
protein; n=1; Paracoccus denitrificans PD1222|Rep:
Alcohol dehydrogenase GroES domain protein - Paracoccus
denitrificans (strain Pd 1222)
Length = 330
Score = 111 bits (268), Expect = 2e-23
Identities = 73/241 (30%), Positives = 116/241 (48%), Gaps = 1/241 (0%)
Frame = -1
Query: 847 EFSGTITDVGKKSV-FRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
E++G + +G F G VVVDPN C C CR G+ C + G G+ R+GG
Sbjct: 60 EYAGEVLALGAGVTGFAAGDLVVVDPNIGCGTCPGCRAGRVNLCESLG---AYGVTRNGG 116
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
+A+ V D + P G+ L EP CV +G + + ++ L+ GAG IG L
Sbjct: 117 FAERCVVRADALVPAP-GMDPALAALAEPMGCVLNGLSPLAGRRI-DRALVFGAGPIGML 174
Query: 490 WVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLVTPDVLEKEKQLYDVIIDCTGVGKV 311
+L Q G + V ++++ RL + + G LE+ + D+ +D TGV V
Sbjct: 175 MGIALRQRGAEAIMV-DLDEDRLAMAAEFGLGALAQGTAELERLRHGCDLAVDATGVPAV 233
Query: 310 MEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIGVKINPFSFPNALGWLKAM 131
Y +GG + FG CPP + I+PF+I+ ++L++ G + AL ++A
Sbjct: 234 AARLPEYAANGGNMLYFGVCPPAARIEISPFEIFRRQLSLFGTHSLNHNIAEALEVIQAC 293
Query: 130 G 128
G
Sbjct: 294 G 294
>UniRef50_Q06004 Cluster: Sorbitol dehydrogenase; n=5;
Bacillales|Rep: Sorbitol dehydrogenase - Bacillus
subtilis
Length = 353
Score = 111 bits (266), Expect = 3e-23
Identities = 78/272 (28%), Positives = 133/272 (48%), Gaps = 8/272 (2%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
E +G I VG F+ G +V V+P C C+ C++G+Y C +T + DG
Sbjct: 71 ECAGEIAAVGSSVDQFKVGDRVAVEPGVTCGRCEACKEGRYNLCPDVQFLATPPV--DGA 128
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
+ QY+K+ QD V+L+PD +S E+ L EP+S H R + L G I I+G G +G +
Sbjct: 129 FVQYIKMRQDFVFLIPDSLSYEEAALIEPFSVGIHAAAR-TKLQPGSTIAIMGMGPVGLM 187
Query: 490 WVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGY--RLVTPDVLEKEKQL-----YDVIID 332
V + G + V+++ +RLE K+ + + D LE+ K + DV +
Sbjct: 188 AVAAAKAFGAGTIIVTDLEPLRLEAAKKMGATHIINIREQDALEEIKTITNDRGVDVAWE 247
Query: 331 CTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIGVKINPFSFPNA 152
G ++ + +R GGK + G P ++ +N I D E+ I G+ ++P
Sbjct: 248 TAGNPAALQSALASVRRGGKLAIVG-LPSQNEIPLNVPFIADNEIDIYGIFRYANTYPKG 306
Query: 151 LGWLKAMGNRYVNYEKLGVKTYALSEYESALK 56
+ +L A G V+ + L Y+L + + A++
Sbjct: 307 IEFL-ASG--IVDTKHLVTDQYSLEQTQDAME 335
>UniRef50_Q3IVK2 Cluster: Zinc-containing alcohol dehydrogenase;
n=1; Rhodobacter sphaeroides 2.4.1|Rep: Zinc-containing
alcohol dehydrogenase - Rhodobacter sphaeroides (strain
ATCC 17023 / 2.4.1 / NCIB 8253 / DSM158)
Length = 337
Score = 108 bits (260), Expect = 1e-22
Identities = 75/238 (31%), Positives = 114/238 (47%), Gaps = 10/238 (4%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
EF+G + VG++ R G V V+P+ C C CR GK CL GI +GG
Sbjct: 59 EFAGYVERVGERVQNCRPGDLVSVEPHVYCGCCKPCRLGKPHLCLD---RLAWGINLNGG 115
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
+ QY V D VY +P+G+ E+ L E C HG DR L G+ ++I+G G G +
Sbjct: 116 FEQYATVRMDTVYQVPEGIGPEEAALGEITGCCMHGIDRVGVEL-GDLVVILGGGAAGLI 174
Query: 490 WVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYR-LVTP---DVLEKEKQLYD-----VI 338
G + +SE N R E + GY +V P D+ + L D V+
Sbjct: 175 LARLAELRGAARIVISEPNAARREQIRAF--GYPDVVDPLNEDLAARIGALTDGLGADVV 232
Query: 337 IDCTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIGVKINPFS 164
I+ G + + + HGG+ + FG P A+I P +I+ +E+T++G NP++
Sbjct: 233 IEAAGRAETAAQAVELVCHGGRVLFFGVAAPGTMAAIEPNRIFAREITVVGSIRNPYT 290
>UniRef50_Q8ELI9 Cluster: Sorbitol dehydrogenase; n=2;
Bacillaceae|Rep: Sorbitol dehydrogenase - Oceanobacillus
iheyensis
Length = 326
Score = 107 bits (256), Expect = 5e-22
Identities = 78/278 (28%), Positives = 131/278 (47%), Gaps = 1/278 (0%)
Frame = -1
Query: 847 EFSGTITDVGKKSVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGGW 668
E GT+ + GK + G++V + PN C C++C+ GK C ++GI RDGG+
Sbjct: 61 ELIGTVIETGKSAADFAGKRVAIMPNSFCGKCEYCKVGKTNICTE---KQSLGINRDGGF 117
Query: 667 AQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNLW 488
A+ + V LPD ++ E+ L EP + + H + + K+ I+G G G L
Sbjct: 118 AEEFVISAKYVLSLPDQLTNEKAVLIEPLAVIVHAMKKV-VITEETKVAIIGCGNEGMLA 176
Query: 487 VTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLVTPDVLEKEKQLYDVIIDCTGVGKVM 308
+ LG VT ++ + +L NK+ Y V+ ++L+DV+I+ G +
Sbjct: 177 IAVAEYLG-AQVTAIDVKQNKL---NKVSHSYHNVSTCQSADAEELFDVVIEAAGTSESF 232
Query: 307 EISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIGVKINPFSFPNALGW-LKAM 131
E L+ GG +V G PP A++ +I KE+TI G I ++FP ++ +
Sbjct: 233 EQGIQLLKPGGAFVAIG-MPP--HANLPVVEIVRKEVTIYGSII--YNFPEDFNTSIEFL 287
Query: 130 GNRYVNYEKLGVKTYALSEYESALKDLRAGLVXKAMFK 17
E + K +++EYE A +G K + K
Sbjct: 288 LQEDFQVEPVISKILSVNEYEKAYTYAVSGDYGKIILK 325
>UniRef50_Q5KJK1 Cluster: Zinc-binding dehydrogenase, putative;
n=16; Dikarya|Rep: Zinc-binding dehydrogenase, putative
- Cryptococcus neoformans (Filobasidiella neoformans)
Length = 349
Score = 105 bits (253), Expect = 1e-21
Identities = 76/289 (26%), Positives = 130/289 (44%), Gaps = 12/289 (4%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
E G I +G K F G ++ D C C +CRKG +C + G+ RDGG
Sbjct: 64 EAVGRIVSMGDKVKGFDIGDRIAADVGETCGYCHYCRKGTDLFCENF---APAGVARDGG 120
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
+A Y+K + Y + + ++ E+ L EP SC HG D + G ++L++GAG G +
Sbjct: 121 FADYIKYHFAKCYKIKN-LTDEEATLLEPASCAIHGMD-VLKMPFGARVLLIGAGPTGLI 178
Query: 490 WVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLVTPD----------VLEKEKQLYDV 341
+ G +T++ +++EI K+E + D + E +DV
Sbjct: 179 LAQLMKMGGASHITIAANTGIKMEIARKVEAADEYIDLDRSNPGPQWAKLKEDNPYGFDV 238
Query: 340 IIDCTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQAS-INPFQIYDKELTIIGVKINPFS 164
+ + TGV ++ + NY+ GG +++G + S +P I+ E IIG +
Sbjct: 239 VAEATGVESLVNDAINYVTRGGTLLVYGVYEDKARLSGWSPTDIFVNEKRIIGSFSQTYC 298
Query: 163 FPNALGWLKAMGNRYVNYEKLGVKTYALSEYESALKDLRAGLVXKAMFK 17
FP A+ L + G + + + LS+Y+ AL + + K K
Sbjct: 299 FPRAIDLLDS-GK--IKTTGMVTDVFPLSDYQGALDKMASRKALKIAIK 344
>UniRef50_Q4LED8 Cluster: Dehydrogenase; n=1; uncultured
crenarchaeote 10-H-08|Rep: Dehydrogenase - uncultured
crenarchaeote 10-H-08
Length = 366
Score = 104 bits (250), Expect = 2e-21
Identities = 82/290 (28%), Positives = 137/290 (47%), Gaps = 13/290 (4%)
Frame = -1
Query: 847 EFSGTITDVGKKSVFRN-GQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
EF+G + +VG++ + N G +VV + C C +C+ G++ C G + +G DG
Sbjct: 81 EFAGVVVEVGEEVDWVNVGDEVVAANSAPCGYCIYCKLGRFNLCENLG-ETIIGFSVDGA 139
Query: 670 WAQYVKVPQDQV----YLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGI 503
+A+Y+K+P+ V Y LP G+ L EP +CV G R + VG+ + +VGAG
Sbjct: 140 YAEYIKLPRRIVTFNLYKLPKGLEPRVAALLEPLACVVRG-QRLIHIDVGDAVAVVGAGP 198
Query: 502 IGNLWVTSLHQLGHRDVTVSEMNKVRLEIVNKL------ETGYRLVTPDVLEKEKQL-YD 344
IG L + G R V V ++N RL ++L +G VLE+ + D
Sbjct: 199 IGLLHMLLSRLSGARKVIVLDVNWNRLRFASELGADIVVNSGEEDARKRVLEETGGIGAD 258
Query: 343 VIIDCTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIG-VKINPF 167
V+I+ G+ + E + +R GG + FG P + + + I+ EL++ G P
Sbjct: 259 VVIEAVGLPETWERALTLVRKGGTVLFFGGPPGGTKLTADTHTIHYGELSLHGSFHHTPQ 318
Query: 166 SFPNALGWLKAMGNRYVNYEKLGVKTYALSEYESALKDLRAGLVXKAMFK 17
A L+ + ++ + +EKL L + ++LR G K K
Sbjct: 319 DVVRA---LRLLESKKLPFEKLITGEARLEDIHRVFEELRQGKHIKVAIK 365
>UniRef50_Q81V29 Cluster: Alcohol dehydrogenase, zinc-containing;
n=19; Bacteria|Rep: Alcohol dehydrogenase,
zinc-containing - Bacillus anthracis
Length = 350
Score = 102 bits (245), Expect = 1e-20
Identities = 79/278 (28%), Positives = 129/278 (46%), Gaps = 13/278 (4%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
EFSG + ++G+ + + G +VVV+P +C C+ C+ G Y C + G GG
Sbjct: 70 EFSGEVVEIGEGVTSHKVGDRVVVEPIYSCGKCEACKHGHYNVCEQLVFHGLGG--EGGG 127
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
+++Y VP+D V+ +PD ++ EQG L EP + H R S L GE + + G G IG L
Sbjct: 128 FSEYTVVPEDMVHHIPDEMTYEQGALVEPAAVAVHAV-RQSKLKEGEAVAVFGCGPIGLL 186
Query: 490 WVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRL--VTPDVLEKEKQL-----YDVIID 332
+ + G V E++K R E+ Y L T DVL + + L +V +
Sbjct: 187 VIQAAKAAGATPVIAVELSKERQELAKLAGADYVLNPATQDVLAEIRNLTNSLGVNVSFE 246
Query: 331 CTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIGVKINPFSFPNA 152
TGV V+ + G+ V+ A+I P + KE ++G+ FP
Sbjct: 247 VTGVEVVLRQAIESTSFEGQTVIVSVW--EKDATITPNNLVLKEKEVVGILGYRHIFPAV 304
Query: 151 LGWLKAMGNRYVNYEKLGVKTYALSE-----YESALKD 53
+K + + + EKL K + + +E+ +KD
Sbjct: 305 ---IKLISSGQIQAEKLITKKITVDQVVEEGFEALVKD 339
>UniRef50_A3JMN6 Cluster: Dehydrogenase; n=4; Bacteria|Rep:
Dehydrogenase - Rhodobacterales bacterium HTCC2150
Length = 346
Score = 101 bits (243), Expect = 2e-20
Identities = 79/289 (27%), Positives = 135/289 (46%), Gaps = 11/289 (3%)
Frame = -1
Query: 847 EFSGTITDVGKKSV-FRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
E SGT+ +G + GQKVVV P C+ C C G + C +G+ DG
Sbjct: 66 EMSGTVEAIGANVTNVKMGQKVVVRPLDHCNDCPACDAGHFHICHQLNF---LGLDTDGA 122
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
+ VP +++LPD + + L EP + H R S L GE ++++G G IG L
Sbjct: 123 MQEIWTVPAHTLHVLPDDLRLDHAALIEPVAVACHDV-RMSDLKEGEDVVVIGGGPIGIL 181
Query: 490 WVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLVTPDVLEKEKQL--------YDVII 335
G R V VSE+NK RL I KL G++++ P ++ + ++ DV+
Sbjct: 182 VAMVARDYGGR-VVVSEVNKARLAIAQKL--GFKIINPAEVDLKAEINTITGEKGADVVF 238
Query: 334 DCTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIGVKI-NPFSFP 158
+ +G ++ G+ V+ + I+ FQ + +EL+++GV++ P +
Sbjct: 239 EVSGTQPGVDAMTEVAATRGRIVMVAI--HAQKPKIDLFQFFWRELSLVGVRVYEPVDYE 296
Query: 157 NALGWLKAMGNRYVNYEKLGVKTYALSEYESALKDL-RAGLVXKAMFKI 14
A+G + + G V+ + LS+ + A DL R+ K++ K+
Sbjct: 297 KAIGIIASGG---VDANTVITDVAPLSDIQKAFDDLDRSPTALKSLIKV 342
>UniRef50_Q5V6U8 Cluster: Zinc-binding dehydrogenase; n=1;
Haloarcula marismortui|Rep: Zinc-binding dehydrogenase -
Haloarcula marismortui (Halobacterium marismortui)
Length = 343
Score = 101 bits (242), Expect = 2e-20
Identities = 65/229 (28%), Positives = 109/229 (47%), Gaps = 8/229 (3%)
Frame = -1
Query: 847 EFSGTITDVGKKSVFRN-GQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
E +G + +VG+ G +V ++P C C C++G Y C + +T DG
Sbjct: 63 ESAGKVVEVGENVTDHEPGDRVALEPGVPCRRCAHCKRGDYHLCESVRFMATPP--HDGA 120
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
+ +YV P D Y LP+ VST +G LCEP S H R S + G+ +LI GAG IG +
Sbjct: 121 FTEYVSWPADFAYTLPESVSTAEGALCEPLSVGIHACRRGS-VGTGDTVLITGAGPIGLM 179
Query: 490 WVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRL-VTPDVLEKEKQLY------DVIID 332
+ + G D+ ++++ K +LE K + VT L+ Y DV+++
Sbjct: 180 VLEAARAAGATDIILTDVVKEKLEFAEKRGADLTVDVTETDLDTAVAEYTDGVGADVVVE 239
Query: 331 CTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIG 185
+G ++ + + +R GG VL G + + ++ D E+ + G
Sbjct: 240 ASGAEPSIKSTIDVVRRGGTVVLVGLASEA-EVPFDVLELIDNEVDVHG 287
>UniRef50_Q92YT8 Cluster: Putative; n=2; Alphaproteobacteria|Rep:
Putative - Rhizobium meliloti (Sinorhizobium meliloti)
Length = 341
Score = 100 bits (239), Expect = 5e-20
Identities = 63/208 (30%), Positives = 98/208 (47%), Gaps = 7/208 (3%)
Frame = -1
Query: 847 EFSGTITDVGKKSV-FRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
EF GTI ++G + G +VV D N C C +CR+ + C G +GI RDG
Sbjct: 60 EFCGTIAEIGASVTHLKTGMRVVADINIGCGNCYWCRRNEVLNC---GEVEQIGIGRDGA 116
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
+AQYV +P V +PDGV L EP +CV +A G +++GAG IGNL
Sbjct: 117 FAQYVALPGRLVLPVPDGVPEAVLALVEPVACVVRAARKAGAAF-GRSGVVLGAGPIGNL 175
Query: 490 WVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLVTPDVLEKE------KQLYDVIIDC 329
V + +G + V++++ R + + + P L + + D +++
Sbjct: 176 HVQMMRLVGMAPIIVADLSSERCRMAVEAGADAAVSEPATLRSKVLEMTGGRGADFVVES 235
Query: 328 TGVGKVMEISFNYLRHGGKYVLFGCCPP 245
G K+ +F+ +R GG FG PP
Sbjct: 236 VGSSKLYRQAFDLVRKGGHVAFFGITPP 263
>UniRef50_P39400 Cluster: Uncharacterized zinc-type alcohol
dehydrogenase-like protein yjjN; n=29;
Gammaproteobacteria|Rep: Uncharacterized zinc-type
alcohol dehydrogenase-like protein yjjN - Escherichia
coli (strain K12)
Length = 337
Score = 100 bits (239), Expect = 5e-20
Identities = 80/251 (31%), Positives = 123/251 (49%), Gaps = 11/251 (4%)
Frame = -1
Query: 847 EFSGTITDVGKKSV-FRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
E G I +GK +NGQ+V V P AC C C+ G+ C S +G+ +DGG
Sbjct: 60 EICGEIVGLGKNIADLKNGQQVAVIPYVACQQCPACKSGRTNCCEKI---SVIGVHQDGG 116
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
+++Y+ VP + L DG+ + L EP++ AH RA+ + GE++L+VGAG IG L
Sbjct: 117 FSEYLSVPVANI-LPADGIDPQAAALIEPFAISAHAVRRAA-IAPGEQVLVVGAGPIG-L 173
Query: 490 WVTSLHQLGHRDVTVSEMNKVRLE-IVNKLETGYRLVTPDVLEKEKQ--------LYDVI 338
++ + V V++ + R E + +LE L+ P + + Q L +
Sbjct: 174 GAAAIAKADGAQVVVADTSPARREHVATRLE--LPLLDPSAEDFDAQLRAQFGGSLAQKV 231
Query: 337 IDCTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIGVK-INPFSF 161
ID TG M + N +RHGG V G Q S +P + + KE T++G + P F
Sbjct: 232 IDATGNQHAMNNTVNLIRHGGTVVFVGLFKGELQFS-DP-EFHKKETTMMGSRNATPEDF 289
Query: 160 PNALGWLKAMG 128
+G L A G
Sbjct: 290 AK-VGRLMAEG 299
>UniRef50_Q38ZV8 Cluster: Zinc-containing alcohol dehydrogenase
superfamily; n=17; Proteobacteria|Rep: Zinc-containing
alcohol dehydrogenase superfamily - Burkholderia sp.
(strain 383) (Burkholderia cepacia (strain ATCC 17760/
NCIB 9086 / R18194))
Length = 373
Score = 99 bits (238), Expect = 7e-20
Identities = 67/229 (29%), Positives = 103/229 (44%), Gaps = 11/229 (4%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
EF GT+ +VG+ + R G +V V+P CS C +CR G Y C++ G G+ DGG
Sbjct: 71 EFCGTVVEVGEGVTALRAGDRVAVEPEYRCSQCAYCRSGSYNLCVSMGF---AGLMGDGG 127
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
A + VP ++ LPDGVS EQ + EP + H R L +GE + G G IG L
Sbjct: 128 MADFAVVPAYMLHRLPDGVSLEQAAVMEPAAVALHAL-RRGELRLGETCAVFGLGPIGLL 186
Query: 490 WVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGY----RLVTPDVLEKEKQL------YDV 341
+ G + +++ RL + + R + L+ + D
Sbjct: 187 LIMLAKLQGATTIVAVDVSPERLAAATRFGATHTFDARALGASALQDAIRAATGGLGVDA 246
Query: 340 IIDCTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELT 194
+ G+ E + + LR GG+ V+ G P A + F+ + ELT
Sbjct: 247 SFEAAGLQTTFESAMHALRKGGRIVMVGLMP---HAGFDAFRAVNDELT 292
>UniRef50_Q02912 Cluster: Sorbitol dehydrogenase; n=1; Bombyx
mori|Rep: Sorbitol dehydrogenase - Bombyx mori (Silk
moth)
Length = 348
Score = 99.5 bits (237), Expect = 9e-20
Identities = 75/289 (25%), Positives = 136/289 (47%), Gaps = 11/289 (3%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
E +GT+ VG K S R G +V ++P + C C+ C++GKY C+ S++G G
Sbjct: 66 EGAGTVVKVGDKVSSLRVGDRVAIEPTQPCRSCELCKRGKYNLCVEPRYCSSMG--APGN 123
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
+Y K D + LPD ++ E+G +P + V H +RA + +G KI+I+GAG IG L
Sbjct: 124 LCRYYKHVADFCHKLPDNLTMEEGAAVQPLAIVIHACNRAK-ITLGSKIVILGAGPIGIL 182
Query: 490 WVTSLHQLGHRDVTVSEMNKVRLEIV------NKLETGYRLVTPDVLEKEKQLY----DV 341
S +G + ++++ + RL+ N L +V+EK +L DV
Sbjct: 183 CAMSAKAMGASKIILTDVVQSRLDAALELGADNVLLVRREYTDEEVVEKIVKLLGDRPDV 242
Query: 340 IIDCTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIGVKINPFSF 161
ID G G ++ + G ++ G T + ++ Q +E+ ++G ++
Sbjct: 243 SIDACGYGSAQRVALLVTKTAGLVLVVGIADKTVELPLS--QALLREVDVVGSFRIMNTY 300
Query: 160 PNALGWLKAMGNRYVNYEKLGVKTYALSEYESALKDLRAGLVXKAMFKI 14
AL A+ + + +K + L++ + AL ++G K + +
Sbjct: 301 QPALA---AVSSGAIPLDKFITHRFPLNKTKEALDLAKSGAAMKILIHV 346
>UniRef50_A6VRA2 Cluster: Alcohol dehydrogenase GroES domain
protein; n=2; Oceanospirillales|Rep: Alcohol
dehydrogenase GroES domain protein - Marinomonas sp.
MWYL1
Length = 340
Score = 99.1 bits (236), Expect = 1e-19
Identities = 73/245 (29%), Positives = 115/245 (46%), Gaps = 12/245 (4%)
Frame = -1
Query: 847 EFSGTITDVGKKSVF-RNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
EFSG + VG+ + G KV VDP +C C CR G++ C + G+ R+GG
Sbjct: 60 EFSGVVAAVGEGVTHVKIGDKVCVDPVISCGECYACRAGRFNVCAKLQV---FGVHRNGG 116
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
+ ++ P V +LPD V+ EQ L EPYS + R P + G+ +L+ GAG+IG
Sbjct: 117 FGEFTSAPASNVLVLPDNVTLEQAALVEPYSIATNVLSRMEP-IPGDTLLVYGAGVIGLT 175
Query: 490 WVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLVTPDVL-EKEKQLYDVIIDCT-GVG 317
V +G + V+++ + +LET L DV+ +E ++ D I + T G G
Sbjct: 176 IVQVAKAMGIERIIVTDI------VDERLETAKSLGATDVINSREHKVEDCIREWTNGEG 229
Query: 316 KVMEISFNYLRHGGKYVLFGCCP---------PTHQASINPFQIYDKELTIIGVKINPFS 164
+ + +L CP T + + ++ KELTI+G ++N
Sbjct: 230 VPLIADAACIPALLPEILRIACPAGRIGLLGFSTTPSDLAQIEVIKKELTIVGSRLNNRR 289
Query: 163 FPNAL 149
FP L
Sbjct: 290 FPQVL 294
>UniRef50_A5JSX4 Cluster: Zinc-containing alcohol dehydrogenase;
n=1; Bacillus megaterium|Rep: Zinc-containing alcohol
dehydrogenase - Bacillus megaterium
Length = 343
Score = 99.1 bits (236), Expect = 1e-19
Identities = 52/142 (36%), Positives = 85/142 (59%)
Frame = -1
Query: 847 EFSGTITDVGKKSVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGGW 668
EFSG I ++ ++ F G +V V+P +C C+ C KG++ C + +GI +DGG+
Sbjct: 60 EFSGVIEEIRGETEFSLGDRVAVEPTLSCGTCEACVKGQFHVCKQLKL---IGIDQDGGF 116
Query: 667 AQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNLW 488
AQ+V VP ++++LLP+ +S+E L EP + H R S L VG++ +I+GAG IG L
Sbjct: 117 AQHVAVPVNRLHLLPEKLSSEHAALAEPVAVAVHTV-RRSRLKVGDQAVILGAGPIGLLI 175
Query: 487 VTSLHQLGHRDVTVSEMNKVRL 422
+ G + V +S+++ RL
Sbjct: 176 GMIAKRAGAKKVMISDISSYRL 197
>UniRef50_A7II35 Cluster: Alcohol dehydrogenase GroES domain
protein; n=1; Xanthobacter autotrophicus Py2|Rep:
Alcohol dehydrogenase GroES domain protein -
Xanthobacter sp. (strain Py2)
Length = 345
Score = 98.7 bits (235), Expect = 2e-19
Identities = 67/245 (27%), Positives = 109/245 (44%), Gaps = 9/245 (3%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWR--D 677
E SG + +G S G V V+P+R C CD+CR G+ C + I+
Sbjct: 63 EISGEVIKLGASVSTLALGDHVAVNPSRPCLECDYCRAGRSNLCRNMRFFGSAAIYPHVQ 122
Query: 676 GGWAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIG 497
G +++ DQ +P + + + EP S HG RA L G+++LI GAG IG
Sbjct: 123 GAFSETFVCRADQCVSVPRDIPFRRVAMAEPLSVAIHGVRRAGEL-AGKRVLIAGAGPIG 181
Query: 496 NLWVTSLHQLGHRDVTVSEMNKVRLEIVNKL---ETGYRLVTPDVL---EKEKQLYDVII 335
L + ++G + ++++ LE+ ET P+ L EK+K +D +
Sbjct: 182 MLLAIAARRVGASYIAITDIVDAPLELARAAGVDETINVATAPEQLARYEKDKGFFDAAL 241
Query: 334 DCTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIGVKINPFSFPN 155
+ TGV + + F +R GG+ V G PP + + +E+ +G F
Sbjct: 242 EATGVPQALASLFKVVRPGGRVVQLGMMPP-GDVPVPANMLMAREIDFVGAFRFSGEFAT 300
Query: 154 ALGWL 140
A+ WL
Sbjct: 301 AVDWL 305
>UniRef50_A0JVZ3 Cluster: Alcohol dehydrogenase GroES domain
protein; n=1; Arthrobacter sp. FB24|Rep: Alcohol
dehydrogenase GroES domain protein - Arthrobacter sp.
(strain FB24)
Length = 350
Score = 97.9 bits (233), Expect = 3e-19
Identities = 70/259 (27%), Positives = 123/259 (47%), Gaps = 10/259 (3%)
Frame = -1
Query: 796 GQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGGWAQYVKVPQDQVYLLPDG 617
G +VVVDP C C C++G+ YC + G ++G R GG+A Y+ +++ G
Sbjct: 86 GSEVVVDPTVFCGDCPSCKRGQPGYCASFG---SLGCDRSGGFADYMIASASKIFPT-GG 141
Query: 616 VSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNLWVTSLHQLGHRDVTVSEM 437
+ + L EP +C HG D + L +LI GAG G + L G VTV+
Sbjct: 142 LHPDIAVLTEPTACALHGVDVLA-LKPASDVLIFGAGPTGLILAQLLRMAGAARVTVAAP 200
Query: 436 NKVRLEIVNKLETGYRL----VTPDVLEKEKQL-----YDVIIDCTGVGKVMEISFNYLR 284
+L + K + + PD +E + +D +I+ TG V+E+ + R
Sbjct: 201 TASKLAVALKQGANHAVQIDRANPDAAAEELRRIAPEGFDAVIEATGSTSVLELGLSLTR 260
Query: 283 HGGKYVLFGCCPPTHQASINPFQIYDKELTIIGVKINPFSFPNALG-WLKAMGNRYVNYE 107
+GG +++G A + P++++ +ELTI G F+ N +G L A+ + ++
Sbjct: 261 NGGTVLVYGLAGENALAVVKPYEVFSRELTIKG----SFAQANCIGRALFALQSGQISTA 316
Query: 106 KLGVKTYALSEYESALKDL 50
+ L ++++AL +L
Sbjct: 317 GIVTSVVNLDQFQTALDNL 335
>UniRef50_O97479 Cluster: CG1982-PA; n=17; Bilateria|Rep: CG1982-PA
- Drosophila melanogaster (Fruit fly)
Length = 360
Score = 96.3 bits (229), Expect = 9e-19
Identities = 79/281 (28%), Positives = 128/281 (45%), Gaps = 11/281 (3%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
E +G + +GKK + + G +V ++P C CD C++GKY C +T DG
Sbjct: 67 ESAGVVAKLGKKVTTLKVGDRVAIEPGVPCRKCDHCKQGKYNLCPGMVFCATPPY--DGN 124
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
+Y K D + LPD V+ E+G L EP S H RA + +G K+LI+GAG IG +
Sbjct: 125 LTRYYKHAADFCFKLPDHVTMEEGALLEPLSVGVHACKRAE-VTLGSKVLILGAGPIGLV 183
Query: 490 WVTSLHQLGHRDVTVSEMNKVRLEIVNKL-ETGYRLVTPDVLEKEKQLY---------DV 341
+ + +G ++ ++++ + RL++ +L T L+ D +E + D
Sbjct: 184 TLMAAQAMGASEILITDLVQQRLDVAKELGATHTLLLKRDQTAEETAVLVQKTMGGQPDK 243
Query: 340 IIDCTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIGVKINPFSF 161
IDC G ++ R GG V+ G + + +E+ I GV +
Sbjct: 244 SIDCCGAESSARLAIFATRSGGIVVVVGM--GAAEIKLPLINALAREVDIRGVFRYCNDY 301
Query: 160 PNALGWLKAMGNRYVNYEKLGVKTYALSEYESALKDLRAGL 38
AL L A G VN ++L + + E A + R GL
Sbjct: 302 AAALA-LVASGK--VNVKRLVTHHFDIKETAKAFETSRKGL 339
>UniRef50_A1CFY8 Cluster: Xylitol dehydrogenase; n=22;
Ascomycota|Rep: Xylitol dehydrogenase - Aspergillus
clavatus
Length = 380
Score = 96.3 bits (229), Expect = 9e-19
Identities = 79/288 (27%), Positives = 123/288 (42%), Gaps = 13/288 (4%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
E SG + VG + + G +V ++P C C+ C+ GKY C +T DG
Sbjct: 95 ESSGVVAKVGSAVTSLKVGDRVAMEPGVPCRRCEPCKAGKYNLCEKMAFAATPPY--DGT 152
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
A+Y +P+D Y LP+ +S ++G L EP H R + + GE +++ GAG +G L
Sbjct: 153 LAKYYPLPEDFCYKLPENISLQEGALMEPLGVAVH-ITRQASIKPGESVVVFGAGPVGLL 211
Query: 490 WVTSLHQLGHRDVTVSEMNKVRLEIVNKLETG--------YRLVTPDVLEKEKQL---YD 344
G + ++ K RL+ K + D + +E L D
Sbjct: 212 CCAVARAFGASKIIAVDIQKTRLDFAKKYAATAIFEPAKVSAVANADQMREENDLGPGAD 271
Query: 343 VIIDCTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIG-VKINPF 167
V+ID +G + + LR GG YV G ++ + KELTI G +
Sbjct: 272 VVIDASGAEPSVHTGIHVLRPGGTYVQGGM--GRNEINFPIMAACTKELTIKGSFRYGSG 329
Query: 166 SFPNALGWLKAMGNRYVNYEKLGVKTYALSEYESALKDLRAGLVXKAM 23
+ A+ L A G VN + L E E A K+++AG K +
Sbjct: 330 DYKLAVD-LVASGK--VNVKDLITGVVEFQEAEQAFKEVKAGKGIKTL 374
>UniRef50_UPI00015970BD Cluster: GutB1; n=1; Bacillus
amyloliquefaciens FZB42|Rep: GutB1 - Bacillus
amyloliquefaciens FZB42
Length = 348
Score = 94.7 bits (225), Expect = 3e-18
Identities = 63/227 (27%), Positives = 116/227 (51%), Gaps = 6/227 (2%)
Frame = -1
Query: 847 EFSGTITDVGKKSV-FRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
E G + ++G + G +VV+DP + C C +CR+G YC T + +GI G
Sbjct: 60 ESVGAVVEIGPDVTNVKVGDRVVIDPTQFCGKCHYCRRGLTCYCETFE-DWQLGIGAHGT 118
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
+A+Y +Y +PD + E+ L EP SCV + D+AS + + +L++G+G IG L
Sbjct: 119 FAEYYVGEDRFMYRIPDSMEWERATLVEPLSCVLNVVDKAS-IQPEDSVLVLGSGPIGLL 177
Query: 490 WVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGY---RLVTPDVLEKEKQ--LYDVIIDCT 326
+ +L R +E+ R E +++ +T D +++ Q +DVI D
Sbjct: 178 VQMMVKKLA-RLTVATEIGSFRSEAASRISDYVYHPEALTVDEVKRINQGRKFDVIFD-- 234
Query: 325 GVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIG 185
+G ++ ++ ++ GG+ V G T++ ++ P+Q+ +TI+G
Sbjct: 235 AIGNQLDWAYPFIEKGGRIVPMG-FDDTYEMTVRPYQLLSNGVTIVG 280
>UniRef50_Q7N973 Cluster: Similarities with different types of
deshydrogenases; n=1; Photorhabdus luminescens subsp.
laumondii|Rep: Similarities with different types of
deshydrogenases - Photorhabdus luminescens subsp.
laumondii
Length = 353
Score = 94.7 bits (225), Expect = 3e-18
Identities = 67/229 (29%), Positives = 110/229 (48%), Gaps = 8/229 (3%)
Frame = -1
Query: 847 EFSGTITDVGKKSV-FRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
E +G IT +GK F G +VV++P +C C C+ G +C + + G+ DG
Sbjct: 61 ETTGVITQIGKSVTRFNVGDRVVINPTYSCGHCRMCQTGSPNHC-EKKLGTEAGVSYDGA 119
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
+A+ + + L D VS E+ L EP SC G D+ + + GAG +G L
Sbjct: 120 FAEQYLAKESSLIKLDDHVSMEEASLTEPLSCTLTGVDKLGITHTNIRAAVAGAGPMGML 179
Query: 490 WVTSLHQLGHRDVTVSEMNKVRLEIVNK-LETGYRLVT---PDVLEK---EKQLYDVIID 332
++ +LH G + V E N+ R++ + L L T +++K + L D+ +D
Sbjct: 180 YIWALHARGVKAFMV-EKNESRIQFAKENLPPECELYTDFDEALIQKYGDKSALIDLCVD 238
Query: 331 CTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIG 185
T G++ E F +L GGK L A+++ +I DK L++IG
Sbjct: 239 TT--GQLTEYVFEHLAPGGK--LLNVALKDKHANLDILKIADKSLSVIG 283
>UniRef50_Q46N56 Cluster: Zinc-containing alcohol dehydrogenase
superfamily; n=2; Burkholderiales|Rep: Zinc-containing
alcohol dehydrogenase superfamily - Ralstonia eutropha
(strain JMP134) (Alcaligenes eutrophus)
Length = 337
Score = 94.7 bits (225), Expect = 3e-18
Identities = 76/275 (27%), Positives = 126/275 (45%), Gaps = 4/275 (1%)
Frame = -1
Query: 847 EFSGTITDVGKKSVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGGW 668
EF+GT+ ++ GQ+V +P C CD+C +G+ C G+ VG+ R G
Sbjct: 60 EFAGTVIASSDEARMPVGQRVTANPLVTCGHCDYCLQGRDNLCANRGM---VGMNRPGAL 116
Query: 667 AQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYD---RA-SPLLVGEKILIVGAGII 500
++Y+ +P +PD + + L EP + H + RA S L +LI+G G I
Sbjct: 117 SEYLAIPIRCAIPIPDTLPSVSAALTEPAATALHAVNLTMRAMSRPLPEVSVLIIGGGAI 176
Query: 499 GNLWVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLVTPDVLEKEKQLYDVIIDCTGV 320
G L + G + V V+E N +R V++ G ++ P V + +DV+ID G
Sbjct: 177 GMLTAALVTSYGCKRVCVAETNALRQASVSR-HLGCEVIDPTVSPPPESAFDVVIDAVGA 235
Query: 319 GKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIGVKINPFSFPNALGWL 140
++ R GG + G + I+ ++ ELT++G S +A
Sbjct: 236 APTRNLAIAATRPGGVVMHIGL--QAWSSEIDMRKLTLAELTLLGTYTYTMSDMHATVRA 293
Query: 139 KAMGNRYVNYEKLGVKTYALSEYESALKDLRAGLV 35
GN + + E V+T +L++ +A DL AG V
Sbjct: 294 LEQGN-FGSLE--WVETRSLADGPAAFADLAAGRV 325
>UniRef50_A5FCD7 Cluster: Alcohol dehydrogenase, zinc-binding domain
protein; n=5; Bacteria|Rep: Alcohol dehydrogenase,
zinc-binding domain protein - Flavobacterium johnsoniae
UW101
Length = 356
Score = 94.3 bits (224), Expect = 3e-18
Identities = 64/196 (32%), Positives = 96/196 (48%), Gaps = 8/196 (4%)
Frame = -1
Query: 820 GKKSVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGGWAQYVKVPQD 641
G + F+ G KV P C C CR G C+ + G+ DGG A+YV +P+
Sbjct: 87 GNAAGFKPGDKVTFIPYFNCGTCVACRNGLTNCCVNIKV---FGVHIDGGMAEYVSIPE- 142
Query: 640 QVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNLWVTSLHQLGH 461
Q L G+ ++ L EP + AHG RA+ + + +L++GAG IG + + ++
Sbjct: 143 QYLLHGQGLDYDELALVEPLAIAAHGVRRAA-VKSTDTVLVMGAGPIG-IGLIQFAKIAG 200
Query: 460 RDVTVSEMNKVRLEIVNKLETGYRLVTP---DVLEKEKQLYD-----VIIDCTGVGKVME 305
V V ++N RL + P DV K +L + V+ID TG KVM
Sbjct: 201 AKVIVMDINDYRLNFCKTELNADETINPLNDDVAAKLAELTNGDMANVVIDATGNQKVMN 260
Query: 304 ISFNYLRHGGKYVLFG 257
+FNY+ HGG++VL G
Sbjct: 261 SAFNYISHGGRFVLVG 276
>UniRef50_A1HSQ8 Cluster: Alcohol dehydrogenase GroES domain
protein; n=1; Thermosinus carboxydivorans Nor1|Rep:
Alcohol dehydrogenase GroES domain protein - Thermosinus
carboxydivorans Nor1
Length = 340
Score = 94.3 bits (224), Expect = 3e-18
Identities = 65/227 (28%), Positives = 110/227 (48%), Gaps = 8/227 (3%)
Frame = -1
Query: 796 GQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGGWAQYVKVPQDQVYLLPDG 617
G +V +D +C C CR ++ C + +G+ DG + +Y+K+ D++Y LP
Sbjct: 79 GDRVAIDNVFSCGRCYACRSNRHNVCREVKV---LGVHIDGVFQEYIKITADKLYKLPAD 135
Query: 616 VSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNLWVTSLHQLGHRDVTVSEM 437
+ E EPYS A DRA + + +L+ GAG IG + + + +LG R V V ++
Sbjct: 136 LPWEMAATVEPYSIAAEAVDRAG-VTKDDTVLVCGAGPIGLVILQASKRLGAR-VAVMDI 193
Query: 436 NKVRLEIVNKLETGYRLVT--PDVLEKEKQL-----YDVIIDCTGVGKVMEISF-NYLRH 281
RLE + + T D+LE ++ +++++ TG V+E++ +
Sbjct: 194 VASRLERAKAMGADLTINTRETDLLEAVREFAGGEGVNIVMEATGNIGVLELAVAKLVSQ 253
Query: 280 GGKYVLFGCCPPTHQASINPFQIYDKELTIIGVKINPFSFPNALGWL 140
GK ++ G P A I P I +EL I G ++N FP + WL
Sbjct: 254 AGKVIVLGF--PVEPAKIVPADIMRRELDIKGSRLNNKKFPEVIRWL 298
>UniRef50_P36624 Cluster: Putative sorbitol dehydrogenase; n=1;
Schizosaccharomyces pombe|Rep: Putative sorbitol
dehydrogenase - Schizosaccharomyces pombe (Fission
yeast)
Length = 360
Score = 94.3 bits (224), Expect = 3e-18
Identities = 70/239 (29%), Positives = 105/239 (43%), Gaps = 18/239 (7%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
E +G + +VGK S + G V V+P C LCD+CR G+Y C +T DG
Sbjct: 68 ESAGVVVEVGKGVSSLKPGDPVAVEPGCVCRLCDYCRSGRYNLCPHMEFAATPPY--DGT 125
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
Y +D LP +S E+G L EP S H R + L G ++L++G G +G L
Sbjct: 126 LRTYYITTEDFCTKLPKQISVEEGALFEPMSVAVHAMTRGN-LKCGSRVLVMGCGTVGLL 184
Query: 490 WVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLVTP----------DVLEKEKQL--- 350
+ G D+ + + R+E K G + TP D ++ KQ
Sbjct: 185 MMAVAKAYGAIDIVAVDASPSRVEFAQKY-VGAKPFTPIAAKENESLPDYAQRYKQAIIE 243
Query: 349 ----YDVIIDCTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIG 185
+D +D TGVG + + L+ GG +V G P IN I + E+ ++G
Sbjct: 244 KYGEFDFAVDATGVGICIHTAVLALKRGGTFVQAGNGKPVIDFPIN--HIINYEINVLG 300
>UniRef50_A6BDE4 Cluster: Putative uncharacterized protein; n=2;
Clostridiales|Rep: Putative uncharacterized protein -
Dorea longicatena DSM 13814
Length = 347
Score = 93.9 bits (223), Expect = 5e-18
Identities = 76/272 (27%), Positives = 119/272 (43%), Gaps = 10/272 (3%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
E SG + +GK +VF GQKV ++P C C CR GKY C + +G G
Sbjct: 66 EVSGEVVKLGKDVTVFHEGQKVTIEPQVYCGECYPCRHGKYNLCEELKV---MGFQTTGT 122
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
++Y V +V +P+ +S E+G + EP + HG + + G I ++GAG IGNL
Sbjct: 123 ASEYFAVDASKVTPIPEEMSYEEGAMIEPLAVAVHGVKQVGD-VKGMNIAVLGAGPIGNL 181
Query: 490 WVTSLHQLGHRDVTVSEMNKVRLE---------IVNKLETGYRLVTPDVLEKEKQLYDVI 338
+ +G V +++++ +RL+ VN E + + +K DVI
Sbjct: 182 VAQAAKGMGAAKVMITDVSDLRLDKAKECGIDVCVNTKEKDFGEAMLETFGPDKA--DVI 239
Query: 337 IDCTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIGVKINPFSFP 158
DC G M + Y R G VL A I+ D EL I + +
Sbjct: 240 YDCAGNNITMGQAIKYARKGSIIVLVAVF--AGMAEIDLAVANDHELDIKSTMM--YRHD 295
Query: 157 NALGWLKAMGNRYVNYEKLGVKTYALSEYESA 62
+ + ++ + V+ L KT+A EY A
Sbjct: 296 DYVDGIRLVNEEKVHLRPLISKTFAFQEYLKA 327
>UniRef50_A5D5N1 Cluster: Threonine dehydrogenase and related
Zn-dependent dehydrogenases; n=1; Pelotomaculum
thermopropionicum SI|Rep: Threonine dehydrogenase and
related Zn-dependent dehydrogenases - Pelotomaculum
thermopropionicum SI
Length = 343
Score = 93.9 bits (223), Expect = 5e-18
Identities = 60/209 (28%), Positives = 106/209 (50%), Gaps = 12/209 (5%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
E+SG + VG + ++F+ G +V+ + NR C +C CR+G+ C + N G+ DGG
Sbjct: 64 EYSGYVEAVGPQVTLFKPGDRVLGESNRYCGVCPNCRRGRTNICDS---NLMTGLHVDGG 120
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
A+++ VPQ V+ +P+ +S ++ L +P S H S + + + + G GI+G +
Sbjct: 121 MAEFIAVPQKLVHHIPENLSFDEATLAQPCSVSFHAVFDNSGIRPNDMVAVFGPGIVGLM 180
Query: 490 WVTSLHQLGHRDVTV---SEMNKVRLEIVNKLETGYRLVT---PDVLE-----KEKQLYD 344
LG +V V E + RL + KL G++ + D+L K+ D
Sbjct: 181 AAQGARLLGAAEVVVIGTGEDAQNRLPVAQKL--GFKTINIGEQDLLAGFAGITGKERAD 238
Query: 343 VIIDCTGVGKVMEISFNYLRHGGKYVLFG 257
V+++C+G K + +F ++ GG L G
Sbjct: 239 VVLECSGAVKALADAFRLVKKGGSITLVG 267
>UniRef50_Q3ACJ3 Cluster: Sorbitol dehydrogenase; n=1;
Carboxydothermus hydrogenoformans Z-2901|Rep: Sorbitol
dehydrogenase - Carboxydothermus hydrogenoformans
(strain Z-2901 / DSM 6008)
Length = 345
Score = 93.1 bits (221), Expect = 8e-18
Identities = 75/275 (27%), Positives = 122/275 (44%), Gaps = 9/275 (3%)
Frame = -1
Query: 847 EFSGTITDVGKKSVFRN--GQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDG 674
E GT+ +VG+ V R GQ+V+VDP C C+ CR G Y C + + DG
Sbjct: 63 EIVGTVIEVGE-GVNRELLGQRVIVDPGENCGQCEHCRTGAYNLCSFSKFKGIPPV--DG 119
Query: 673 GWAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGN 494
G A+Y+ V LP+ + + L EP+S D A G KI ++G G +G
Sbjct: 120 GMAEYITALATHVIPLPENLDSPTATLLEPFSVGLQAVDVAD-FRAGAKIAVLGGGPVGV 178
Query: 493 LWVTSLHQLGHRDVTVSEMNKVRLEIVNKL--ETGYRLVTPDVLE-----KEKQLYDVII 335
L + G D+ ++E+ + R+EI KL E + D L+ +K DV+
Sbjct: 179 LTAIAAKIRGCGDLWLTELYERRIEIARKLGIEKVINVAQEDPLKTIMEVTKKSGVDVVF 238
Query: 334 DCTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIGVKINPFSFPN 155
+ TG K +E + ++ GG V G + IN Q+ L ++G + F
Sbjct: 239 ETTGNPKAVEQALQIVKRGGTVVFLGI--GAGKVPINIDQVTRTGLKLLGSFRYQYHFAG 296
Query: 154 ALGWLKAMGNRYVNYEKLGVKTYALSEYESALKDL 50
A+ +K +++ L Y + AL+++
Sbjct: 297 AVALVK---KHNLDFSPLVTNIYDFVDIPKALEEV 328
>UniRef50_Q9K5Y6 Cluster: L-iditol 2-dehydrogenase; n=8;
Bacteria|Rep: L-iditol 2-dehydrogenase - Bacillus
halodurans
Length = 348
Score = 92.7 bits (220), Expect = 1e-17
Identities = 77/264 (29%), Positives = 121/264 (45%), Gaps = 6/264 (2%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
EFSG + +VG + G +VVV+P AC C C++GKY C G G GG
Sbjct: 71 EFSGQVVEVGDGVTKCEEGDRVVVEPIFACGTCTACKQGKYNLCEQLGFLGLAG--GGGG 128
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
+++YV V + V+ +PD VS EQG L EP + VA R S VG++ ++ G G IG L
Sbjct: 129 FSEYVTVDEHMVHKIPDTVSFEQGALVEP-AAVALYAVRQSQFNVGDQAVVFGTGPIGLL 187
Query: 490 WVTSLHQLGHRDVTVSEMNKVRLEIVNKL-ETGYRLVTPDVLEKEKQL----YDVIIDCT 326
+ +L G + E++ R + +L +V+E+ ++L DV + T
Sbjct: 188 VIEALKASGASKIYAVELSTERRQRAEQLGAIALNPAEVNVVEEIQRLTDGGADVSFEVT 247
Query: 325 GVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIGVKINPFSFPNALG 146
GV V+ + + G+ ++ +AS P + +E I G+ FP
Sbjct: 248 GVPIVLTQAIESTKLNGQTMIVSIF--EKEASFQPNLVVMRERNIAGIIGYRDIFPAV-- 303
Query: 145 WLKAMGNRYVNYEKLGVKTYALSE 74
+ M Y + E L K L +
Sbjct: 304 -ISLMNQGYFSAETLVTKRIGLHD 326
>UniRef50_Q48FD6 Cluster: Oxidoreductase, zinc-binding; n=2;
Pseudomonas syringae group|Rep: Oxidoreductase,
zinc-binding - Pseudomonas syringae pv. phaseolicola
(strain 1448A / Race 6)
Length = 340
Score = 92.7 bits (220), Expect = 1e-17
Identities = 64/201 (31%), Positives = 100/201 (49%), Gaps = 4/201 (1%)
Frame = -1
Query: 847 EFSGTITDVGKKSV-FRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGIN--STVGIWRD 677
E G I DVG+ V + G +VVVDPN C +C+ CR K C AG G+ +
Sbjct: 60 EAVGIIIDVGEGVVHLQKGMRVVVDPNEYCGVCEPCRLAKTHLCNGAGNAGLDIAGVNKH 119
Query: 676 GGWAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIG 497
G +A+ + VY LPD +S G L EP +C+ + D+A + GE++LI+G+G +
Sbjct: 120 GTFAERFVTRERFVYQLPDDMSWAAGVLVEPVACILNNIDQAF-IRAGERVLILGSGPMS 178
Query: 496 NLWVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLVTPDVLEKEKQ-LYDVIIDCTGV 320
+ L +G D ++ N R++ L+ + Q +DV+ID V
Sbjct: 179 LIAQIVLRSMG-IDTLATDRNTHRIQFGRSQSLDVIHANDLELQMQHQEKFDVVIDT--V 235
Query: 319 GKVMEISFNYLRHGGKYVLFG 257
G ++ + Y+ GG+ VLFG
Sbjct: 236 GNQIDTASRYIGRGGRIVLFG 256
>UniRef50_A0TC93 Cluster: Alcohol dehydrogenase GroES-like; n=15;
Proteobacteria|Rep: Alcohol dehydrogenase GroES-like -
Burkholderia ambifaria MC40-6
Length = 358
Score = 92.7 bits (220), Expect = 1e-17
Identities = 67/227 (29%), Positives = 106/227 (46%), Gaps = 6/227 (2%)
Frame = -1
Query: 847 EFSGTITDVGKKSVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGGW 668
E S + + + G V V P +C C CR+GK C+ + +G+ RDG
Sbjct: 83 ELSAIVAEADPGAHVAPGDAVYVMPYLSCGQCIACRQGKTNCCVNIKV---LGVHRDGAL 139
Query: 667 AQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNLW 488
+Y+ VP V+ +GV+ +Q + E + AH RA+ + G++IL+VGAG IG +
Sbjct: 140 TEYLSVPAQFVHKA-EGVTLDQAAMIEFLAIGAHAVRRAA-VSAGQRILVVGAGPIG-MA 196
Query: 487 VTSLHQLGHRDVTVSEMNKVRLEI------VNKLETGYRLVTPDVLEKEKQLYDVIIDCT 326
QL VT + RL V ++TG V + +DV+ D T
Sbjct: 197 AMLFAQLRGAHVTCLDTRADRLAFCREHFAVATVQTGPNDVDELSTMTNGEFFDVVFDAT 256
Query: 325 GVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIG 185
G K M F ++ HGGKYVL P + + + + + +E T++G
Sbjct: 257 GNVKAMNRGFEFIAHGGKYVLISIVP--GEITFSDPEFHKREATLLG 301
>UniRef50_Q9Z9U1 Cluster: Sorbitol dehydrogenase; n=14;
Bacillales|Rep: Sorbitol dehydrogenase - Bacillus
halodurans
Length = 343
Score = 92.7 bits (220), Expect = 1e-17
Identities = 77/287 (26%), Positives = 132/287 (45%), Gaps = 12/287 (4%)
Frame = -1
Query: 847 EFSGTITDVGKKSV-FRNGQKVVVDPNRA-CSLCDFCRKGKYQYCLTAGINSTVGIWRDG 674
EFSG I ++G+ F G +V + + C C +C G Y C +G +DG
Sbjct: 61 EFSGEIVELGEGVTGFNVGDRVTSETTYSICGKCSYCTSGDYNLC---SHRKGLGNQQDG 117
Query: 673 GWAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGN 494
+A+YV Q+ ++ LP GV + EP +C H + S + G+ +++ G G IG
Sbjct: 118 SFAKYVIARQESLHHLPAGVDDRSAAMTEPLACTHHAIAKTS-INKGDLVVVTGPGPIGL 176
Query: 493 L--WVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLVTPDVLEKE--KQL-----YDV 341
L V H G +T ++VRL+ ++ Y + T +V KE +L DV
Sbjct: 177 LAAQVAKSHG-GTVIITGLSNDQVRLKKAKEVGIDYAIDTQEVDIKELVSELTDGYGADV 235
Query: 340 IIDCTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIGVKI-NPFS 164
+++C+G + + LR G+Y G + N +I KE++++G + P
Sbjct: 236 VLECSGAVPAAKQGIDLLRKKGQYAQVGLFAQP-EIQFNFEKIIQKEISVVGSRSQKPAD 294
Query: 163 FPNALGWLKAMGNRYVNYEKLGVKTYALSEYESALKDLRAGLVXKAM 23
+ AL L + VN + L Y +SE++ A +++G K +
Sbjct: 295 WEPALSLL---NEKKVNAKTLVTHEYTISEWDKAYHAIKSGEAIKVL 338
>UniRef50_Q12E06 Cluster: Alcohol dehydrogenase GroES-like; n=2;
Bacteria|Rep: Alcohol dehydrogenase GroES-like -
Polaromonas sp. (strain JS666 / ATCC BAA-500)
Length = 346
Score = 91.9 bits (218), Expect = 2e-17
Identities = 68/234 (29%), Positives = 110/234 (47%), Gaps = 13/234 (5%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
EF+G + VG + F+ G +V +DP C C +C+ G CL +G DG
Sbjct: 61 EFAGEVVQVGDGVTQFKTGDRVCMDPVIPCRACAYCKTGHENVCLH---RQAMGYEFDGA 117
Query: 670 WAQYVKVP-----QDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAG 506
+A+Y+++P V+++P +S E L EP +C +G R + + VG+ ++++GAG
Sbjct: 118 FAEYIRIPAIALTAGNVFMMPAQMSFESAALAEPLACCING-QRNAGVQVGDTVVVLGAG 176
Query: 505 IIGNLWVTSLHQLGHRDVTVSEMNKVRLE--IVNKLETGYRLVTPDVLEKEKQL-----Y 347
IG + G R V VSE N R + + +E T V+E K
Sbjct: 177 PIGLMHAALARLSGARQVIVSEPNAARRQAAVDRGVEHMCDPSTESVMEFVKARTDGLGA 236
Query: 346 DVIIDCTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIG 185
DV+I GV ++ S N +R GG LF ++I+ I+ E+ + G
Sbjct: 237 DVVILAIGVPQLANESLNLVRKGGHVNLFAGFSAGETSNIDVNLIHYNEIVVTG 290
>UniRef50_Q8R9L6 Cluster: Threonine dehydrogenase and related
Zn-dependent dehydrogenases; n=4; Clostridia|Rep:
Threonine dehydrogenase and related Zn-dependent
dehydrogenases - Thermoanaerobacter tengcongensis
Length = 317
Score = 91.5 bits (217), Expect = 2e-17
Identities = 68/265 (25%), Positives = 129/265 (48%), Gaps = 3/265 (1%)
Frame = -1
Query: 847 EFSGTITDVGKKSVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIW-RDGG 671
EF G + D + G++VV D N AC CD C++G + +C +GI+ +DG
Sbjct: 55 EFVGIVEDSSNPQLI--GKRVVADINIACGECDLCKEGLFHHCRN---RKVLGIFEKDGA 109
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
+A+Y+ +P ++++PD + E+ EP + + + +K++++G G +
Sbjct: 110 FAEYITLPNRNLFIVPDSIKDEEAVFTEPLAAALEILEMYH-IKPTDKVVVIGDGKLSQ- 167
Query: 490 WVTSLHQLGHRDVTVSEMNKVRLE-IVNKLETGYRLVTPDVLEKE-KQLYDVIIDCTGVG 317
++T + L D+ V ++ +LE + NK T L+ +V E K ++DV I+CTG
Sbjct: 168 FITQVVALTGCDLYVVGKHEEKLEHLKNKANT---LLLEEVERLETKSVFDVAIECTGNE 224
Query: 316 KVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIGVKINPFSFPNALGWLK 137
++++ ++ G +L A++NP E+ +IG + P + L+
Sbjct: 225 DGLKLAQQLVKPTGTVILKSTY--NAYATLNPTDWVVNEIKLIGTRCGPMA-----SALR 277
Query: 136 AMGNRYVNYEKLGVKTYALSEYESA 62
+ R+V + L Y L +YE A
Sbjct: 278 LLEKRFVTTDYLISGFYKLEQYEEA 302
>UniRef50_Q8EMM7 Cluster: Dehydrogenase; n=1; Oceanobacillus
iheyensis|Rep: Dehydrogenase - Oceanobacillus iheyensis
Length = 338
Score = 90.6 bits (215), Expect = 4e-17
Identities = 69/212 (32%), Positives = 102/212 (48%), Gaps = 10/212 (4%)
Frame = -1
Query: 847 EFSGTITDVGKKSVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGGW 668
EFSGTI + G ++ + G +V V+P C C C+ G C + VGI DGG
Sbjct: 60 EFSGTIEE-GHPTL-KKGTRVTVNPLLRCGECYPCQNGYSHVCENLKL---VGIDCDGGM 114
Query: 667 AQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNLW 488
+YVKVP + L D +S + G L EP + H R + G+ ++I GAG IG
Sbjct: 115 GEYVKVPIHSIVPLKDNISMKLGALIEPVAVAVHAI-RQGNYMPGDSVVIFGAGTIGLCV 173
Query: 487 VTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLVTP---DVLEK-----EKQLYDVIID 332
+L G +++ + E NK+RLE +L G++ + P +V EK + D + D
Sbjct: 174 ALTLRSYGAKNLIIVEPNKLRLEKAKQL--GFQTLDPLSENVTEKIVEGTDNIGADYVFD 231
Query: 331 CTGVGKVMEISFNYLRHGGKYVLFGCC--PPT 242
C G V+E +R G V+ PPT
Sbjct: 232 CAGHPSVVEAITEVVRVRGNIVIVAMYKQPPT 263
>UniRef50_Q1Q2R9 Cluster: Similar to sorbitol dehydrogenase; n=1;
Candidatus Kuenenia stuttgartiensis|Rep: Similar to
sorbitol dehydrogenase - Candidatus Kuenenia
stuttgartiensis
Length = 339
Score = 90.6 bits (215), Expect = 4e-17
Identities = 59/224 (26%), Positives = 108/224 (48%), Gaps = 11/224 (4%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
E +G I +G F+ G +V V + C+ C +C G + C T + + GG
Sbjct: 57 EIAGEIVAIGDAVKQFKVGDRVTVAHHVPCNTCHYCLNGHHSVCDTLRTTN----FYPGG 112
Query: 670 WAQYVKVPQDQV----YLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGI 503
+A++++VPQ V ++LP +S ++G EP +C G R S G+ +L++G+GI
Sbjct: 113 FAEFLRVPQINVDRGTFILPQEMSYDEGTFVEPLACSIRG-QRLSNFKPGQSLLVIGSGI 171
Query: 502 IGNLWVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLVT----PDVLEKEK--QLYDV 341
G L + LG + +++N+ RL+ K+ + P ++ K+ +L D+
Sbjct: 172 SGLLHIQLARALGAGKIFATDINEYRLKFAKKIGADIAINAKEDVPSIIRKDNNGRLADL 231
Query: 340 IIDCTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIY 209
I CTG E +F+ + GG + F P + I+ + ++
Sbjct: 232 AIVCTGAISATEQAFHSIERGGTILFFAPTEPGVKIPIDLWNLW 275
>UniRef50_A5D4M1 Cluster: Zn-dependent alcohol dehydrogenases; n=1;
Pelotomaculum thermopropionicum SI|Rep: Zn-dependent
alcohol dehydrogenases - Pelotomaculum thermopropionicum
SI
Length = 372
Score = 90.6 bits (215), Expect = 4e-17
Identities = 69/235 (29%), Positives = 120/235 (51%), Gaps = 14/235 (5%)
Frame = -1
Query: 847 EFSGTITDVGK--KSVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDG 674
E +GT+ VG + G++V V P C C FC++G++ CL GI DG
Sbjct: 83 EVAGTVERVGPGVRGDLSPGKRVAVYPIAVCGECFFCKRGRHNLCLRE-YGLAHGI--DG 139
Query: 673 GWAQYVKVPQDQVYL-----LPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGA 509
G+AQYV++P++ V + LP+ +S EQ + EP SC RA L G+ +L+VGA
Sbjct: 140 GFAQYVRIPREIVAIGGLVELPEHLSYEQAAMAEPLSCCL-AAARAGKLEEGDTMLVVGA 198
Query: 508 GIIGNLWVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLVT--PDVLEKEKQLYD--- 344
G +G L + + G R V V+++ + RLE+ ++ + + DV+E+ ++L D
Sbjct: 199 GPMGLLHLKTGLWRGAR-VIVADLRRDRLEMAARMGAAHCIDAGEKDVVEEVRRLTDGLG 257
Query: 343 --VIIDCTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIG 185
+++ G + +R+GG + +FG P +++ I+ E+ + G
Sbjct: 258 AGLVVASLGAPEAAAQYLPAVRNGGTFNIFGGPPANRPVNVDFRWIHYSEVVLTG 312
>UniRef50_A3H8A1 Cluster: Alcohol dehydrogenase GroES-like; n=1;
Caldivirga maquilingensis IC-167|Rep: Alcohol
dehydrogenase GroES-like - Caldivirga maquilingensis
IC-167
Length = 337
Score = 90.6 bits (215), Expect = 4e-17
Identities = 62/204 (30%), Positives = 100/204 (49%), Gaps = 7/204 (3%)
Frame = -1
Query: 847 EFSGTITDVGKKSVFRN-GQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
EF+G + + G G+ V+P C C +CR G C+ I +GI G
Sbjct: 60 EFTGIVEEAGPGVPKEYIGRLFTVNPIIGCGHCRYCRSGLKNLCVMRKI---IGIDYPGA 116
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
+A+YV VP D +Y + D V +G L EP + R S + +G+ +L++GAG +G+L
Sbjct: 117 YAEYVAVPVDNLYPVSDPV---KGALAEPLATSLRAV-RLSGVSLGDSVLVIGAGPVGSL 172
Query: 490 WVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLVT--PDVLEKEKQLY----DVIIDC 329
+ L+ G +D+T ++N RLE + L T + L+ ++LY D +ID
Sbjct: 173 AIKLLNIGGIKDITAIDINANRLEWARRWGASKTLSTTGEEALKTIRELYPEGFDAVIDA 232
Query: 328 TGVGKVMEISFNYLRHGGKYVLFG 257
G ++ N +R GG+ V G
Sbjct: 233 VGSTDTRRLAINTVRRGGRVVFVG 256
>UniRef50_Q44P31 Cluster: Zinc-containing alcohol dehydrogenase
superfamily; n=3; Chlorobiaceae|Rep: Zinc-containing
alcohol dehydrogenase superfamily - Chlorobium limicola
DSM 245
Length = 421
Score = 90.2 bits (214), Expect = 6e-17
Identities = 67/263 (25%), Positives = 118/263 (44%), Gaps = 2/263 (0%)
Frame = -1
Query: 811 SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGGWAQYVKVPQDQVY 632
S + + ++V V P +C C FC G+ C + I +G DGG+A+YV V + +
Sbjct: 163 SGYLDNERVAVWPGISCGSCAFCLAGRENLCASMQI---LGFHHDGGFAEYVAVRRTSLL 219
Query: 631 LLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNLWVTSLHQLGHRDV 452
+PD + E L EP C HG DRA + GE++LI GAG +G + G V
Sbjct: 220 SVPDTLPMELAALAEPLGCALHGLDRAG-VRSGERVLIYGAGSLGLFLALGAAERGAHPV 278
Query: 451 TVSEMNKVRLEIVNKLETGYRLVTPDVLEKEKQLYDVIIDCTGVGKVMEISFNYLRHGGK 272
+ E + +L + + + + + L+D + V ++ LR GG+
Sbjct: 279 VI-EPDGRKLRKSHTFRDRFAIGSAETPSVVSGLFDAAFNAASVPSTLD-GLRKLRSGGR 336
Query: 271 YVLFGCCPPTHQASINPFQ-IYDKELTIIG-VKINPFSFPNALGWLKAMGNRYVNYEKLG 98
Y LF +++ + F ++ +EL ++G S +AL L+ G + +
Sbjct: 337 YCLFSGLQELPESAASLFAGLHYRELQLLGSYGCTRASMASALAMLERFGG---DLAFMV 393
Query: 97 VKTYALSEYESALKDLRAGLVXK 29
+ + + E+A+ D+ G K
Sbjct: 394 ERKLPIEQLEAAMPDVIGGKYFK 416
>UniRef50_A3DCE7 Cluster: Alcohol dehydrogenase GroES-like protein;
n=1; Clostridium thermocellum ATCC 27405|Rep: Alcohol
dehydrogenase GroES-like protein - Clostridium
thermocellum (strain ATCC 27405 / DSM 1237)
Length = 344
Score = 89.8 bits (213), Expect = 7e-17
Identities = 67/227 (29%), Positives = 105/227 (46%), Gaps = 8/227 (3%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
E SG I +V + + GQKV ++P C C CR GKY C + +G G
Sbjct: 60 EVSGKIVEVAEDVEHLKVGQKVTIEPQVVCGKCHPCRTGKYNLCEELKV---MGFQTVGA 116
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
++Y V V +PD +S ++ + EP + H +R + + I+++GAG IG L
Sbjct: 117 GSEYFAVDAKNVTTVPDHLSYDEAAMIEPLAVTVHAANRVGD-VKDKDIVVIGAGPIGIL 175
Query: 490 WVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLVT--PDVLEKEKQLY-----DVIID 332
V +L G R V V++++ RLE+ K + + T D E + + DVI D
Sbjct: 176 LVQTLKAKGARKVMVTDVSDYRLELALKCGADFAVNTKKEDFGEAMLRCFGPDKADVIYD 235
Query: 331 CTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTI 191
C G ME + + R G VL A+++ + DKEL +
Sbjct: 236 CAGNNTTMEQAIKHSRKGSIIVLVAVF--EGMATVDLATLNDKELDL 280
>UniRef50_A5D1M5 Cluster: Threonine dehydrogenase and related
Zn-dependent dehydrogenases; n=1; Pelotomaculum
thermopropionicum SI|Rep: Threonine dehydrogenase and
related Zn-dependent dehydrogenases - Pelotomaculum
thermopropionicum SI
Length = 329
Score = 89.4 bits (212), Expect = 1e-16
Identities = 61/223 (27%), Positives = 107/223 (47%), Gaps = 1/223 (0%)
Frame = -1
Query: 847 EFSGTITDVGKKSV-FRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
EFSG + +VG R G +VV DP C C +CR+ +Y C G +G R G
Sbjct: 60 EFSGVVEEVGAGVTGLRPGDQVVGDPRVPCGRCQWCRREQYNLCPGLGF---IGEVRPGC 116
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
+A+++ + ++ +P + ++ L EP + H + L + I+GAG IG L
Sbjct: 117 FAEHIAINYKKLLKVP-ALDLKEAVLVEPLAVAVH-IAKKGKLSPENTVGILGAGPIGLL 174
Query: 490 WVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLVTPDVLEKEKQLYDVIIDCTGVGKV 311
+ + + R+V V + + RLEI K+ + + E L DV+++ G G
Sbjct: 175 TLAAAKAIRVREVIVVDPSPARLEIARKICADSAVAA--IPEDPADLADVVVEAAGTGSA 232
Query: 310 MEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIGV 182
+ + +L+ GG+ V+ G + ++P I ++EL I G+
Sbjct: 233 LAGALKWLKPGGRLVMAGIY--EDRVQLDPNNIINRELKIAGI 273
>UniRef50_Q4WT02 Cluster: Xylitol dehydrogenase; n=8;
Pezizomycotina|Rep: Xylitol dehydrogenase - Aspergillus
fumigatus (Sartorya fumigata)
Length = 383
Score = 89.4 bits (212), Expect = 1e-16
Identities = 67/249 (26%), Positives = 107/249 (42%), Gaps = 11/249 (4%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
E SG I G + G +V ++P +C+ C +CR G Y C + +T DG
Sbjct: 91 ESSGVIVACGSNVDGLKVGDRVALEPGISCNTCKYCRSGHYNLCKSMVFAATPPY--DGT 148
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
+ + KVP + Y LP +S G L EP S H R + + + +++ GAG +G L
Sbjct: 149 LSTFYKVPAECCYKLPVHISLRDGALVEPLSVAVHAC-RLAGDMQNKSVVVFGAGPVGLL 207
Query: 490 WVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLVTPDVLEKEKQL---------YDVI 338
+ G V ++ K RL K +R + ++L D+I
Sbjct: 208 CCSVASAFGAAKVVAVDVVKTRLATATKYGATHRYEMDAEKKNAEELSATAALEDGADII 267
Query: 337 IDCTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIG-VKINPFSF 161
+D TG + + LR GG +V G PT + Q+ DKE+ G + P +
Sbjct: 268 LDATGAEPCLNCGLDILRSGGTFVQVGLGNPTLMFPVG--QVCDKEVVFKGSFRYGPGDY 325
Query: 160 PNALGWLKA 134
A+G L++
Sbjct: 326 ALAIGLLES 334
>UniRef50_Q0TXS2 Cluster: Putative uncharacterized protein; n=2;
Pezizomycotina|Rep: Putative uncharacterized protein -
Phaeosphaeria nodorum (Septoria nodorum)
Length = 359
Score = 89.0 bits (211), Expect = 1e-16
Identities = 63/200 (31%), Positives = 97/200 (48%), Gaps = 9/200 (4%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
EFSGT+ VG+ + ++ G +VVV P C C +G C G G W GG
Sbjct: 75 EFSGTVETVGQGVTAYKPGDRVVVQPIIYDGTCGACEEGLQNCCWQNGFVGLSG-W-GGG 132
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
A ++ VP+ +Y LPD V E G L EP + H + SP + LI+G G IG
Sbjct: 133 LADHIVVPESTLYHLPDNVPLEIGALVEPLAVGWHAV-KVSPFKKDDTALILGGGPIGIS 191
Query: 490 WVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLVTP---DVLEKEKQLYD-----VII 335
+ +L G +++ VSE++K R E K + ++ P D++ + ++L D V
Sbjct: 192 TILALKANGCKNIIVSEVSKKRQEFAKKF-GAHHIIDPTKEDMIARTRKLTDNKGAHVTF 250
Query: 334 DCTGVGKVMEISFNYLRHGG 275
DC GV ++ + + R G
Sbjct: 251 DCAGVQAALDQAVHATRARG 270
>UniRef50_UPI0000384B5E Cluster: COG1063: Threonine dehydrogenase and
related Zn-dependent dehydrogenases; n=1;
Magnetospirillum magnetotacticum MS-1|Rep: COG1063:
Threonine dehydrogenase and related Zn-dependent
dehydrogenases - Magnetospirillum magnetotacticum MS-1
Length = 647
Score = 88.6 bits (210), Expect = 2e-16
Identities = 63/228 (27%), Positives = 112/228 (49%), Gaps = 7/228 (3%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWR-DG 674
EFSG + +G+ + F+ G VVV+ ++C C CR G + C + +G++R +G
Sbjct: 373 EFSGHVVSMGQNVTAFKEGDPVVVECIQSCGSCAECRAGNFIGCAE---RTELGVFRRNG 429
Query: 673 GWAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLV-----GEKILIVGA 509
+A +V VP V+ L G Q LCEP + V G R P L ++ + GA
Sbjct: 430 AYADFVTVPARFVHKLAAGTDMAQAALCEPLAVVLKGMRRLMPALAAAPGGAKRAAVTGA 489
Query: 508 GIIGNLWVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLVTPDVLEKEKQLYDVIIDC 329
G IG++ L + G VT+ + N+ RL++ ++ + T L++ + ++V+++
Sbjct: 490 GCIGHICAVELARRGF-PVTIFDRNQSRLDVFKGRDS---IETSTDLDRLGE-FNVVVEA 544
Query: 328 TGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIG 185
TG +V++ + + G +L G + S YDK T++G
Sbjct: 545 TGHPEVLDKALHAAPAGATLLLLGLPYARKEFSFEAIAAYDK--TVVG 590
>UniRef50_Q1ARQ8 Cluster: Alcohol dehydrogenase GroES-like protein
precursor; n=1; Rubrobacter xylanophilus DSM 9941|Rep:
Alcohol dehydrogenase GroES-like protein precursor -
Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 341
Score = 88.6 bits (210), Expect = 2e-16
Identities = 71/246 (28%), Positives = 107/246 (43%), Gaps = 10/246 (4%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
EFSGT+ VG+ G++V V+P +C C CR G C + +GI R G
Sbjct: 60 EFSGTVVAVGEGVDEAWVGRRVAVNPLISCGECRLCRSGHENICPERAL---IGIHRPGA 116
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
+A+YV+VP ++ LP+GV L EP + H E ++VGAG IG +
Sbjct: 117 FAEYVEVPAGSLHALPEGVDLRSAALAEPLANGVHAAGLGLERGPAELAVVVGAGTIGLM 176
Query: 490 WVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLVTPDVLEKEKQL--------YDVII 335
+ + G +V E + R LE G P E E+ + DV++
Sbjct: 177 CLQAAVLSGIPEVWAVEPHGGRR--ARALELGAGRAFPPGGEAEEAVREATGGLGADVVL 234
Query: 334 DCTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIG-VKINPFSFP 158
D G G+ + +R GG VL G + ++ + ++L + G P F
Sbjct: 235 DAAGAGETRRAAARLVRPGGTVVLVGL--HEDETALGFHDVVRRQLALQGSYAYTPRDFE 292
Query: 157 NALGWL 140
ALGWL
Sbjct: 293 RALGWL 298
>UniRef50_A3TNY9 Cluster: Zinc-binding dehydrogenase; n=5;
Actinomycetales|Rep: Zinc-binding dehydrogenase -
Janibacter sp. HTCC2649
Length = 355
Score = 87.4 bits (207), Expect = 4e-16
Identities = 80/275 (29%), Positives = 118/275 (42%), Gaps = 8/275 (2%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
E +G I VG R G++V ++P C C C G Y C ++T I DG
Sbjct: 72 ESAGVIVGVGSGVDPARIGERVAIEPGVPCRSCAQCLAGHYNLCPDMVFHATPPI--DGT 129
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
A+YV P + LPD VS ++G + EP S RA + G ++L+ GAG +G L
Sbjct: 130 LAEYVVHPSSFAFALPDSVSLDEGAMLEPLSVGIWACRRAG-VAPGVRVLVTGAGPVGQL 188
Query: 490 WVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLVTPDVLEKE-KQLY------DVIID 332
G +V V+++N RL + + L T DV K Y DV+++
Sbjct: 189 AAQVAVAFGASEVVVADVNAHRLSVASSLGA---TKTVDVSSKSLADAYAGRPGPDVVLE 245
Query: 331 CTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIGVKINPFSFPNA 152
C+G + + G+ VL G T + Q ++EL + GV ++P A
Sbjct: 246 CSGHEGSTQAAIRVAAPAGRVVLIGMGGDTLALPLGDVQ--NRELWVTGVFRYANTWPTA 303
Query: 151 LGWLKAMGNRYVNYEKLGVKTYALSEYESALKDLR 47
+ L A G VN L + L E AL R
Sbjct: 304 ID-LVASGR--VNLTPLATGHFDLEGTEGALTAAR 335
>UniRef50_Q0UDN4 Cluster: Putative uncharacterized protein; n=2;
Pezizomycotina|Rep: Putative uncharacterized protein -
Phaeosphaeria nodorum (Septoria nodorum)
Length = 363
Score = 87.4 bits (207), Expect = 4e-16
Identities = 60/202 (29%), Positives = 92/202 (45%), Gaps = 8/202 (3%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
EFSGT+T++G + F GQ +VV P C C C+ G C G G GG
Sbjct: 71 EFSGTVTELGPNVTSFSVGQPIVVQPTIYCGKCHACKAGVENVCYNGGFIGLSG--GGGG 128
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
+ V VP+ V LPD V + G L EP S H A+PL ++++G G IG
Sbjct: 129 LSDSVVVPESAVLALPDNVPLDIGALVEPLSVAWHAIS-AAPLTPDSVVMVLGGGPIGLA 187
Query: 490 WVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRL--VTPDVLEKEKQLY-----DVIID 332
V L L + + +SE+++ R + + + T D + ++L D++ D
Sbjct: 188 IVQCLVALNTKTIILSEVSRARQRFAREFGAHHVIDPKTYDTVAISRELSGQDGPDIVFD 247
Query: 331 CTGVGKVMEISFNYLRHGGKYV 266
C GV ++ + +R G V
Sbjct: 248 CAGVPASLKTACTAVRARGTVV 269
>UniRef50_A3PQM0 Cluster: Alcohol dehydrogenase GroES domain
protein; n=1; Rhodobacter sphaeroides ATCC 17029|Rep:
Alcohol dehydrogenase GroES domain protein - Rhodobacter
sphaeroides (strain ATCC 17029 / ATH 2.4.9)
Length = 345
Score = 87.0 bits (206), Expect = 5e-16
Identities = 64/230 (27%), Positives = 107/230 (46%), Gaps = 9/230 (3%)
Frame = -1
Query: 847 EFSGTITDVGKKSVF-RNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIW--RD 677
EFSG I +VG + + G V V+P+R C CD C G C + + +
Sbjct: 63 EFSGRIREVGPGVQWLKPGMAVAVNPSRPCGSCDQCSAGLTHLCRSMRFMGSAAHFPHTH 122
Query: 676 GGWAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIG 497
GG+A+ V Q LP+ V L EPY+ H + A + G +L+ GAG IG
Sbjct: 123 GGFAERPVVLASQCVALPETVDLALAALSEPYAVALHAVELAQ-IAAGASVLVTGAGTIG 181
Query: 496 NLWVTSLHQLGHRDVTVSEMNKVRLEIVNKLETG---YRLVTPDVLEKEKQL---YDVII 335
+L + Q G + V+++ + L V K+ TG + + P+ + DV++
Sbjct: 182 SLVAVAARQAGAGRLIVTDIAEPALARVRKV-TGAETHLVGDPEATRAAEAAIGEVDVVL 240
Query: 334 DCTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIG 185
+ +GV ++++ +R G+ V G PP + S+ I +E T++G
Sbjct: 241 EASGVSAALDMAIRCIRPRGRIVQVGFLPPEARLSLAGLLI--REATLVG 288
>UniRef50_A0NKD6 Cluster: Zc-binding dehydrogenase; n=3; Oenococcus
oeni|Rep: Zc-binding dehydrogenase - Oenococcus oeni
ATCC BAA-1163
Length = 385
Score = 87.0 bits (206), Expect = 5e-16
Identities = 62/208 (29%), Positives = 97/208 (46%), Gaps = 14/208 (6%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTA-GINST---VGIW 683
EF+G + G + G V V+P AC C CR G Y C + G ++ +G
Sbjct: 95 EFAGKVKKTGALVKGLKVGDHVTVEPIIACGYCAACRSGNYNLCENSIGEDNAAGFLGFS 154
Query: 682 RDGGWAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGI 503
+GG +Q V + LPD + G LCEP + A S + G+ +LI GAG
Sbjct: 155 ANGGLSQLCNVSYIYAHKLPDDLPLSLGALCEPTAVAAQAIFN-SKIHAGDDVLISGAGP 213
Query: 502 IGNLWVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLV-------TPDVLEK--EKQL 350
IG L G DV +S+++ RL+I KL G + + T + ++K ++Q
Sbjct: 214 IGLLTAILAKISGAHDVMISDVSTSRLQIAEKLGIGIQTIDLSKKESTQEEVKKLTDRQG 273
Query: 349 YDVIIDCTGVGKVMEISFNYLRHGGKYV 266
D+ +C+G G ++ + L+ GK V
Sbjct: 274 ADIAFECSGNGSALDADIDALKFNGKLV 301
>UniRef50_Q5V6V7 Cluster: Zinc-binding dehydrogenase; n=1;
Haloarcula marismortui|Rep: Zinc-binding dehydrogenase -
Haloarcula marismortui (Halobacterium marismortui)
Length = 344
Score = 87.0 bits (206), Expect = 5e-16
Identities = 60/230 (26%), Positives = 109/230 (47%), Gaps = 9/230 (3%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPNRACSLCDFCRKGKYQYC-LTAGINSTVGIWRDG 674
E +GT+ +VG F G +V ++P C+ C +C+KG+ C I DG
Sbjct: 59 EGAGTVAEVGADVDRFAVGDRVAINPTVPCNACSYCKKGETHLCENNTSIGGAGDTILDG 118
Query: 673 GWAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGN 494
+A+YV+VP V + + +S E+ L EP +C HG ++A + G+ + I+GAG IG
Sbjct: 119 AFAEYVRVPAINVEDIGE-MSFERAALAEPLACCVHGVEQAD-IKPGDSVGIIGAGPIGL 176
Query: 493 LWVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLVTPDVLEKEKQL-------YDVII 335
L + + G + VSE++ R E+ L ++ P+ + E+ + +V
Sbjct: 177 LLLQAFRNAGAAPIVVSELDDERRELAADLGAD-AVIDPNEEDPEEAIPAAAGGPVNVGA 235
Query: 334 DCTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIG 185
+ G+ ++ + GG ++FG ++PF ++ E+ G
Sbjct: 236 EAIGLVPTIKQANAVTAPGGSTLIFGVPDQEATMEVSPFDVFFDEVDYRG 285
>UniRef50_Q16R00 Cluster: Alcohol dehydrogenase; n=3; Culicidae|Rep:
Alcohol dehydrogenase - Aedes aegypti (Yellowfever
mosquito)
Length = 364
Score = 86.6 bits (205), Expect = 7e-16
Identities = 74/291 (25%), Positives = 130/291 (44%), Gaps = 13/291 (4%)
Frame = -1
Query: 847 EFSGTITDVGKKSV-FRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
E +G + VG + + G +V ++P C CD C+ GKY CL G + T DG
Sbjct: 69 ESAGVVRKVGSQVTNLKVGDRVAIEPAAGCRTCDLCKVGKYNICLD-GKHCTTQ-KHDGN 126
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
+ Y D + +PD ++ E+G L EP + + RA + +G K++I GAG IG +
Sbjct: 127 CSNYYAQYADCCFKMPDHMTMEEGALLEPLAVAVYAGRRAQ-IGLGNKVVIFGAGPIGLV 185
Query: 490 WVTSLHQLGHRDVTVSEMN--KVRLEIVNKL-ETGYRLVTPDVLEKE--KQLYDV----- 341
+ + +G + ++ K RLE+ KL TG + + E++ K+++++
Sbjct: 186 CLIAAKAMGATRTVILDLEHAKHRLEVAKKLGVTGVIGIKKEDSEEDLVKKIHEILGGPA 245
Query: 340 --IIDCTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIGVKINPF 167
+++CTG M IS R+ G+ L G + +E+ I
Sbjct: 246 DRVLECTGSQPGMRISIKATRNAGRICLVGL--GNKDVQLPMVDAISREIDITTCMRYNH 303
Query: 166 SFPNALGWLKAMGNRYVNYEKLGVKTYALSEYESALKDLRAGLVXKAMFKI 14
+P A L+ + + YV+ + L + LS+ A + G K M +
Sbjct: 304 DYPAA---LEIVASGYVDVKPLVSHHFDLSDVHEAFRVASQGEGVKIMIHL 351
>UniRef50_Q8ZJN2 Cluster: L-threonine 3-dehydrogenase; n=41;
Bacteria|Rep: L-threonine 3-dehydrogenase - Yersinia
pestis
Length = 341
Score = 86.6 bits (205), Expect = 7e-16
Identities = 64/231 (27%), Positives = 111/231 (48%), Gaps = 9/231 (3%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCL-TAGINSTVGIWRDG 674
E+ G + +G++ F G +V + + C C CR G+ C T G VG+ R G
Sbjct: 64 EYVGEVVAIGQEVKGFNIGDRVSGEGHITCGHCRNCRGGRTHLCRNTVG----VGVNRPG 119
Query: 673 GWAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGN 494
+A+Y+ +P + +PD +S E + +P+ H S LVGE +L+ GAG IG
Sbjct: 120 SFAEYLVIPAFNAFKIPDNISDELAAIFDPFGNAVH--TALSFDLVGEDVLVSGAGPIGI 177
Query: 493 LWVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLVTP-----DVLEK--EKQLYDVII 335
+ +G R V ++++N+ RL++ K+ + DV+ + + +DV +
Sbjct: 178 MAAAVCKHVGARHVVIADVNEYRLDLARKMGVTRAVNVSKENLNDVMTELGMTEGFDVGL 237
Query: 334 DCTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIGV 182
+ +G N + HGG+ + G PP+ SI+ Q+ K L I G+
Sbjct: 238 EMSGAPPAFRSLLNSMNHGGRIAMLG-IPPS-DMSIDWNQVIFKGLFIKGI 286
>UniRef50_A3I7D7 Cluster: Zinc-containing alcohol dehydrogenase,
long-chain; n=1; Bacillus sp. B14905|Rep:
Zinc-containing alcohol dehydrogenase, long-chain -
Bacillus sp. B14905
Length = 339
Score = 86.2 bits (204), Expect = 9e-16
Identities = 70/274 (25%), Positives = 117/274 (42%), Gaps = 9/274 (3%)
Frame = -1
Query: 847 EFSGTITDVGKKSVFRN-GQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
EFSG + +V + G +V V+P C C C++G C + + G GG
Sbjct: 60 EFSGVVVEVAEGVTHTKVGDRVAVEPPIPCGKCANCKRGYSNLCKSG---QSYGYTISGG 116
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
+A+Y V ++ +Y LP+G+S E G L EP + H R S L +G+ I GAG IG L
Sbjct: 117 FAEYAVVREENIYHLPEGMSLELGALVEPTAVAVHAV-RQSQLKLGDTAAIFGAGPIGLL 175
Query: 490 WVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLVTPD------VLEKEKQLYDVIIDC 329
+ ++ G ++ V E++ R + +L Y + D + EK DV D
Sbjct: 176 ILQAVKAAGASEIFVVEVSDERRQKALELGATYVINPIDTDAVAFIREKTNGGVDVAYDA 235
Query: 328 TGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIGVKINPFSFPNAL 149
GV + + GG++ + NP + E+ I G FP +
Sbjct: 236 AGVQATFSSGVSAVHPGGEFKIVSVW--EKPVEFNPNAVVSPEVKISGSFAYVNIFPEVI 293
Query: 148 GWLK--AMGNRYVNYEKLGVKTYALSEYESALKD 53
L + + V ++ ++ +E+ +KD
Sbjct: 294 RLLARGVIDGQAVITSQIALEDIVEKGFEALMKD 327
>UniRef50_Q58D31 Cluster: Sorbitol dehydrogenase; n=8;
Eukaryota|Rep: Sorbitol dehydrogenase - Bos taurus
(Bovine)
Length = 356
Score = 86.2 bits (204), Expect = 9e-16
Identities = 78/287 (27%), Positives = 130/287 (45%), Gaps = 10/287 (3%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
E SGT+ VG + G +V ++P +FC+ G+Y T +T DG
Sbjct: 70 EASGTVVKVGSLVRHLQPGDRVAIEPGAPRETDEFCKIGRYNLSPTIFFCATPP--DDGN 127
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
++ K + Y LPD V+ E+G L EP S H RA + +G K+L+ GAG IG +
Sbjct: 128 LCRFYKHNANFCYKLPDNVTFEEGALIEPLSVGIHACRRAG-VTLGNKVLVCGAGPIGLV 186
Query: 490 WVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRL----VTP-DVLEKEKQLY----DVI 338
+ + +G V V++++ RL ++ + L +P ++ +K + L +V
Sbjct: 187 SLLAAKAMGAAQVVVTDLSASRLSKAKEVGADFILQISNESPQEIAKKVEGLLGSKPEVT 246
Query: 337 IDCTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIGVKINPFSFP 158
I+CTGV ++ GG VL G + S+ +E+ I GV ++P
Sbjct: 247 IECTGVETSIQAGIYATHSGGTLVLVGL--GSEMTSVPLVHAATREVDIKGVFRYCNTWP 304
Query: 157 NALGWLKAMGNRYVNYEKLGVKTYALSEYESALKDLRAGLVXKAMFK 17
A+ L ++ VN + L + L + A + + GL K M K
Sbjct: 305 MAISML---ASKSVNVKPLVTHRFPLEKALEAFETSKKGLGLKVMIK 348
>UniRef50_Q67XB8 Cluster: Sorbitol dehydrogenase-like protein; n=41;
Magnoliophyta|Rep: Sorbitol dehydrogenase-like protein -
Arabidopsis thaliana (Mouse-ear cress)
Length = 364
Score = 85.0 bits (201), Expect = 2e-15
Identities = 69/250 (27%), Positives = 114/250 (45%), Gaps = 14/250 (5%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
E +G I +VG++ G +V ++P +C C+ CR+G+Y C +T + G
Sbjct: 80 ECAGIIEEVGEEVKHLVVGDRVALEPGISCWRCNLCREGRYNLCPEMKFFATPPV--HGS 137
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEK--ILIVGAGIIG 497
A V P D + LP+ VS E+G +CEP S H RA VG + +L++GAG IG
Sbjct: 138 LANQVVHPADLCFKLPENVSLEEGAMCEPLSVGVHACRRAE---VGPETNVLVMGAGPIG 194
Query: 496 NLWVTSLHQLGHRDVTVSEMNKVRLEIVNKL--------ETGYRLVTPDVLEKEKQL--- 350
+ + + + + ++++ RL + +L T V +V + +K +
Sbjct: 195 LVTMLAARAFSVPRIVIVDVDENRLAVAKQLGADEIVQVTTNLEDVGSEVEQIQKAMGSN 254
Query: 349 YDVIIDCTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIGVKINP 170
DV DC G K M + R GGK L G + P +E+ ++GV
Sbjct: 255 IDVTFDCAGFNKTMSTALAATRCGGKVCLVGMGHGIMTVPLTPAAA--REVDVVGVFRYK 312
Query: 169 FSFPNALGWL 140
++P L +L
Sbjct: 313 NTWPLCLEFL 322
>UniRef50_Q98GG6 Cluster: L-iditol 2-dehydrogenase; n=5;
Alphaproteobacteria|Rep: L-iditol 2-dehydrogenase -
Rhizobium loti (Mesorhizobium loti)
Length = 338
Score = 84.6 bits (200), Expect = 3e-15
Identities = 65/228 (28%), Positives = 111/228 (48%), Gaps = 7/228 (3%)
Frame = -1
Query: 847 EFSGTITDVGKKSVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGGW 668
E SGT+ + G+ G+ VV++P +C C CR GK C+ + +G+ RDG
Sbjct: 61 EVSGTVIETGEGPDLAIGEPVVINPYLSCGKCIACRHGKPNCCVKIEV---LGVHRDGAM 117
Query: 667 AQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNLW 488
+ + VP +Y +G+S E + AH RA G + L++GAG IG L
Sbjct: 118 CERILVPAQNLY-PANGLSLADAAAVEFLAIGAHAVRRAR-ADSGARALVIGAGPIG-LG 174
Query: 487 VTSLHQLGHRDVTVSEMNKVRL-----EIVNKLETGYRLVTPDVLE--KEKQLYDVIIDC 329
++ DVT+ +M+ RL E+ + G R PD+++ + +DV+ D
Sbjct: 175 NAIFARIAGLDVTLLDMSSERLAFAENELGFSILDGSRGAVPDLVKDATSGEGFDVVFDA 234
Query: 328 TGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIG 185
TG + ++ +F ++ HGG VL S +P + + +E+T++G
Sbjct: 235 TGNTRSVQSAFAHVAHGGTLVLVSVVKDDIVFS-DP-EFHKREMTLVG 280
>UniRef50_P77280 Cluster: Uncharacterized zinc-type alcohol
dehydrogenase-like protein ydjJ; n=16; Bacteria|Rep:
Uncharacterized zinc-type alcohol dehydrogenase-like
protein ydjJ - Escherichia coli (strain K12)
Length = 347
Score = 84.6 bits (200), Expect = 3e-15
Identities = 62/227 (27%), Positives = 111/227 (48%), Gaps = 8/227 (3%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
E +GT+ VG + F+ G +V ++P C C +C +GKY C +T +R G
Sbjct: 66 ECAGTVVAVGSRVRKFKPGDRVNIEPGVPCGHCRYCLEGKYNICPDVDFMATQPNYR-GA 124
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
Y+ P+ Y LPD + T +G L EP + H A + G+KI+I+GAG IG +
Sbjct: 125 LTHYLCHPESFTYKLPDNMDTMEGALVEPAAVGMHAAMLAD-VKPGKKIIILGAGCIGLM 183
Query: 490 WVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRL--VTPDVLEKEKQL-----YDVIID 332
+ + LG ++ V ++ + RL + +L + D + + +Q D++ +
Sbjct: 184 TLQACKCLGATEIAVVDVLEKRLAMAEQLGATVVINGAKEDTIARCQQFTEDMGADIVFE 243
Query: 331 CTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTI 191
G ++ + + GGK ++ G P ++IN +I ++E+TI
Sbjct: 244 TAGSAVTVKQAPYLVMRGGKIMIVGTVP--GDSAINFLKI-NREVTI 287
>UniRef50_Q8EL78 Cluster: Alcohol dehydrogenase; n=1; Oceanobacillus
iheyensis|Rep: Alcohol dehydrogenase - Oceanobacillus
iheyensis
Length = 351
Score = 84.2 bits (199), Expect = 4e-15
Identities = 61/227 (26%), Positives = 98/227 (43%), Gaps = 7/227 (3%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
EFSG I ++G+ S G +V ++P C C+ C +G Y C G VG+ DG
Sbjct: 71 EFSGVIHEIGEGVSGLSVGDRVAIEPAIKCGKCENCVRGNYNLCEHNGF---VGLQSDGA 127
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
+A+Y V V+ LPD +S E+ EP + H + S + G+ + + G G IG
Sbjct: 128 FAEYAIVDPHMVHKLPDNISFEEATAIEPTAVSFHAL-KLSNMKAGDTVAVFGVGPIGLT 186
Query: 490 WVTSLHQLGHRDVTVSEMNKVRLEIVNKL--ETGYRLVTPDVLEK----EKQLYDVIIDC 329
+ G + +++ RLE+ KL T + + EK + DC
Sbjct: 187 AILCAKAAGASRIYAIDVSNERLEMAQKLGATTVINAIEENAAEKIYAETGSGVTIAFDC 246
Query: 328 TGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTII 188
G + + + L GG+ V+ P +N Q KE+ I+
Sbjct: 247 AGAEATVNSAIDSLAKGGQLVIVSIIP--EPIKVNLLQANLKEINIL 291
>UniRef50_Q65L02 Cluster: Putative uncharacterized protein; n=1;
Bacillus licheniformis ATCC 14580|Rep: Putative
uncharacterized protein - Bacillus licheniformis (strain
DSM 13 / ATCC 14580)
Length = 337
Score = 84.2 bits (199), Expect = 4e-15
Identities = 65/228 (28%), Positives = 106/228 (46%), Gaps = 8/228 (3%)
Frame = -1
Query: 847 EFSGTITDVGKKS-VFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
E SG I + + G +V + P C C CR G+ C+ + +G+ DGG
Sbjct: 60 ELSGEIVSIDNSGGTLKPGDQVSIIPYLECGACIACRNGRPNCCVNLNV---LGVHTDGG 116
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
+Y+ VP D + L +G++ + + E S AH +RA+ + GE +L+VGAG IG L
Sbjct: 117 MREYINVPADHL-LKTEGLTLSEAAVVECLSIGAHAAERAN-IKKGETVLVVGAGPIG-L 173
Query: 490 WVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLVT--PDVLEKEKQLYD-----VIID 332
V +L V ++ K RL + +V ++ K+L + + D
Sbjct: 174 SVMKFAKLKGAKVIAMDVRKERLTFSRRWAEADEVVLGGEHAADEIKRLTNGDFPTAVFD 233
Query: 331 CTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTII 188
TG M ++ Y HGG+ + G H A +P +I+ +ELTI+
Sbjct: 234 ATGHPASMNSAYQYAAHGGRLIYVGLV-NDHLAMPDP-EIHMRELTIL 279
>UniRef50_Q5BBC2 Cluster: Putative uncharacterized protein; n=1;
Emericella nidulans|Rep: Putative uncharacterized
protein - Emericella nidulans (Aspergillus nidulans)
Length = 353
Score = 84.2 bits (199), Expect = 4e-15
Identities = 72/246 (29%), Positives = 107/246 (43%), Gaps = 9/246 (3%)
Frame = -1
Query: 847 EFSGTITDVGKKSV-FRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
EFSGTI +VG+ F+ G +V V PN + C C G+ C + G GG
Sbjct: 70 EFSGTIEEVGQGVTGFKVGDRVAVRPNLSDGTCASCVYGRPNCCRSLGFIGFSS--NSGG 127
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
+ YV VP LLP+ V + G L EP + H R SP L+VG G IG
Sbjct: 128 LSDYVTVPAKHAILLPESVPLDLGALVEPLTVAWHAVAR-SPHETARTALVVGGGPIGLA 186
Query: 490 WVTSLHQLGHRDVTVSEMNKVRLEIVNKLETG--YRLVTPDVLEKEKQL-----YDVIID 332
V L G + V V+E++ R E L + +T DV+ + + L D+ +
Sbjct: 187 VVQVLKARGVQTVVVAEVSTQRREYALTLGATHVFNPLTDDVVARVRSLTDNAGADISFE 246
Query: 331 CTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIGVKI-NPFSFPN 155
C+GV + + N +R G + + I+ F + E +IG I + F
Sbjct: 247 CSGVQAGFDTAMNGIRVRGTTTIVSLW--EKKPMIDAFDVVSYEKHVIGAAICDDGDFEA 304
Query: 154 ALGWLK 137
+G +K
Sbjct: 305 VIGAIK 310
>UniRef50_A3Q0B6 Cluster: Alcohol dehydrogenase GroES domain
protein; n=4; Actinomycetales|Rep: Alcohol dehydrogenase
GroES domain protein - Mycobacterium sp. (strain JLS)
Length = 341
Score = 83.8 bits (198), Expect = 5e-15
Identities = 65/234 (27%), Positives = 104/234 (44%), Gaps = 1/234 (0%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
E SG I VG+ R G++V V+P C C C+ G+Y C +T I DG
Sbjct: 71 ELSGRIAAVGEGVDPGRVGERVAVEPQHPCRRCKQCKAGRYNLCPEMKFYATPPI--DGA 128
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
+ +YV + D + +P+ +S + L EP S VA R + ++ G ILI GAG IG +
Sbjct: 129 FCRYVVIDDDFAHPVPESMSDDAAALLEPLS-VAIATMRKAGVVPGSTILIAGAGPIGVI 187
Query: 490 WVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLVTPDVLEKEKQLYDVIIDCTGVGKV 311
+ G + V+++ R E+ K L V + D +D TGV
Sbjct: 188 CAQAARAFGAARIVVTDLVPSRREMALKFGATEVLDPAAVDVSAIEPVDAFVDATGVPAA 247
Query: 310 MEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIGVKINPFSFPNAL 149
+ + G+ VL G + ++ I + E+T+ GV ++P A+
Sbjct: 248 VVSGIKAVGPAGRVVLVGMGADEYALPVS--HIANLEITVTGVFRYTDTWPAAI 299
>UniRef50_A3DI68 Cluster: Alcohol dehydrogenase GroES-like protein;
n=1; Clostridium thermocellum ATCC 27405|Rep: Alcohol
dehydrogenase GroES-like protein - Clostridium
thermocellum (strain ATCC 27405 / DSM 1237)
Length = 347
Score = 83.4 bits (197), Expect = 6e-15
Identities = 61/209 (29%), Positives = 95/209 (45%), Gaps = 9/209 (4%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
E G ++ +G+ F G KV ++P C C+ CRKG Y C + + +DG
Sbjct: 67 EPGGIVSAIGEGVEGFEIGDKVALEPGVPCGECEDCRKGHYNLCKHIKFMA-IPHEKDGV 125
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
+A+Y Y LP+ V T +GGL EP S H + S +GE +++G+G IG
Sbjct: 126 FAEYCVHSASMCYKLPENVDTMEGGLMEPLSVALHATE-LSNAKIGETAIVLGSGCIGLC 184
Query: 490 WVTSLHQLGHRDVTVSEMNKVRLEIVNKLETG----YRLVTPDVLEKEKQL----YDVII 335
V +L G ++ V+++ RLE LE G + D++E K L D +
Sbjct: 185 TVMALKARGVSEIYVTDVVDKRLE--KALEVGATRVFNSQREDIVEFAKTLPGGGADQVY 242
Query: 334 DCTGVGKVMEISFNYLRHGGKYVLFGCCP 248
+C G + ++ GK L G P
Sbjct: 243 ECAGSRVTTLQTCKLIKRAGKVTLVGVSP 271
>UniRef50_A1UPQ2 Cluster: Alcohol dehydrogenase GroES domain
protein; n=10; Mycobacterium|Rep: Alcohol dehydrogenase
GroES domain protein - Mycobacterium sp. (strain KMS)
Length = 341
Score = 83.4 bits (197), Expect = 6e-15
Identities = 60/202 (29%), Positives = 89/202 (44%), Gaps = 8/202 (3%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
E SG I +VG R GQ V P C C +C + Y C G +G R+GG
Sbjct: 60 EVSGRIVEVGAGVDQSRIGQGAAVIPMDFCGSCHYCHRSLYHLCQRPG---WIGFTRNGG 116
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
A YV VP +PD V E+ L EP + H RA LL+GE ++++GAG +G
Sbjct: 117 LANYVAVPSRLAVRVPDVVDLEEAALTEPTAVAFHAVRRAE-LLLGETVMVLGAGALGLT 175
Query: 490 WVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRL------VTPDVLEKEKQL-YDVIID 332
+ G + V+E + VR + L L T +LE+ + + DV+
Sbjct: 176 VIQCARAAGAARIFVTEPSGVRASLARDLGATLVLDPHDPGTTACILEETRGVGVDVVFH 235
Query: 331 CTGVGKVMEISFNYLRHGGKYV 266
G + + LR G+++
Sbjct: 236 VAGSAEAFTQGLDCLRKQGRFM 257
>UniRef50_A1R5Y9 Cluster: L-threonine 3-dehydrogenase; n=1;
Arthrobacter aurescens TC1|Rep: L-threonine
3-dehydrogenase - Arthrobacter aurescens (strain TC1)
Length = 347
Score = 83.4 bits (197), Expect = 6e-15
Identities = 62/230 (26%), Positives = 101/230 (43%), Gaps = 8/230 (3%)
Frame = -1
Query: 847 EFSGTITDVGKKSV-FRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
E +GT+ ++G + G +V ++ + C C CR G C GI +G+ DG
Sbjct: 66 EGAGTVVEIGPGVTGLKVGDQVALESHLTCGQCFPCRTGDAHTCERTGI---LGMHIDGV 122
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
+A+Y VPQD LP G+S E G L E H RA+ + G +L+ GAG +G +
Sbjct: 123 FAEYAAVPQDICVKLPTGLSLESGALLEAAGVAVHAIQRANYSVAGRAVLVSGAGPVGLV 182
Query: 490 WVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLVTPDVLEKEKQL------YDVIIDC 329
V +G V + N R KL ++E+ ++L +DV +C
Sbjct: 183 VVNLALLMGASHVIAVDPNPYRRAQAEKLGATALHPNDGIVERCRELTGRRGGFDVAFEC 242
Query: 328 TGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASIN-PFQIYDKELTIIGV 182
+G + F +R + G P+ A ++ I K +T+ G+
Sbjct: 243 SGAPGTLATLFEAVRREATVITVG--HPSRPAEVDIAAYINKKGITLRGI 290
>UniRef50_A0V2V8 Cluster: Alcohol dehydrogenase GroES-like; n=1;
Clostridium cellulolyticum H10|Rep: Alcohol
dehydrogenase GroES-like - Clostridium cellulolyticum
H10
Length = 346
Score = 83.4 bits (197), Expect = 6e-15
Identities = 73/275 (26%), Positives = 117/275 (42%), Gaps = 14/275 (5%)
Frame = -1
Query: 805 FRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGGWAQYVKVP-----QD 641
F G+ V V P C +C C+ GK C T+G DGG+A Y+ +P
Sbjct: 75 FEIGEHVAVAPAIGCGICYSCKNGKTNMCEDL---KTIGFQYDGGFADYMVIPLQAFKMG 131
Query: 640 QVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNLWVTSLHQLGH 461
VY LP+ L EP +C + + + GE ++I G+GIIG + G
Sbjct: 132 NVYKLPEVKDDSVFTLSEPLACAINAQSYLN-IKQGEDVVIFGSGIIGCMHAELALYSGA 190
Query: 460 RDVTVSEMNKVRLEIVNKLETGYRLVT---PDVLEKEKQL-----YDVIIDCTGVGKVME 305
++V + E + R++ +KL + D+ + +L DV I VG
Sbjct: 191 KNVIIIETSFERIKQASKLLKDVIFINSAETDIFAEVSRLTDGKGADVAIIACSVGSAQA 250
Query: 304 ISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIGVKIN-PFSFPNALGWLKAMG 128
L G+ LFG I+ I+ +E+++ GV + P A ++ +
Sbjct: 251 DGMKILAKCGRISLFGGLSGNSTGFIDSNLIHYREISVFGVHASTPEQNKQA---MEMIH 307
Query: 127 NRYVNYEKLGVKTYALSEYESALKDLRAGLVXKAM 23
+ +N EK + Y L + E A KD+ G V KA+
Sbjct: 308 SGKINVEKYITERYPLKDIEKAFKDIEDGRVMKAV 342
>UniRef50_A0IRE9 Cluster: Alcohol dehydrogenase GroES-like; n=1;
Serratia proteamaculans 568|Rep: Alcohol dehydrogenase
GroES-like - Serratia proteamaculans 568
Length = 341
Score = 83.4 bits (197), Expect = 6e-15
Identities = 69/217 (31%), Positives = 102/217 (47%), Gaps = 8/217 (3%)
Frame = -1
Query: 811 SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGGWAQYVKVPQDQVY 632
++++ GQ+VVV P R C C CR+G+ C TA S +GI R G +YV V +D +
Sbjct: 77 ALYQPGQQVVVIPYRHCGRCAACRRGR-TTCCTA--LSVMGIHRTGAMQEYVTVAEDAL- 132
Query: 631 LLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNLWVTSLHQLGHRDV 452
L G+ Q L EPY+ AH R S + G +L+VGAG IG L + + + +V
Sbjct: 133 LAVTGIPHLQAALIEPYAIAAHAV-RRSGVTHGVSLLVVGAGAIG-LGIADIGRSLGAEV 190
Query: 451 TVSEMNKVRLEIVNKLETGYRLVTPDVLEKEKQLY--------DVIIDCTGVGKVMEISF 296
V+E + R + ++ P + E+QL VIID TG M
Sbjct: 191 IVAEADPQRQAFAGEQYGFTDVLNPLDTDFEQQLRVLTHSDGPQVIIDATGNPASMNSQV 250
Query: 295 NYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIG 185
+ GG V G T + S N + +EL ++G
Sbjct: 251 ERIAAGGTLVFVGL--HTGEVSFNDLAFHKRELELLG 285
>UniRef50_Q0FV22 Cluster: Sorbitol dehydrogenase; n=1; Roseovarius
sp. HTCC2601|Rep: Sorbitol dehydrogenase - Roseovarius
sp. HTCC2601
Length = 351
Score = 83.0 bits (196), Expect = 9e-15
Identities = 76/285 (26%), Positives = 121/285 (42%), Gaps = 10/285 (3%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
EF+GT+T G+ S G +VV P C C+ CR+G+ C I VG+ RDGG
Sbjct: 67 EFAGTVTATGEGVSRVVTGDRVVCSPTLTCGRCEGCRQGRPSACEARQI---VGLHRDGG 123
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
+A+ V+VP+ ++ LP + E+ L EP S + + A + G+++L++G G IG
Sbjct: 124 FAERVRVPESVLHRLPAAIGFERAALAEPLSIAVNAVNVAE-VAAGDRVLVLGPGPIGLA 182
Query: 490 WVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLVTPDVLEKEKQL---------YDVI 338
+ G + + + RL I E G V D+ E+ D +
Sbjct: 183 CAFVAQERGAKVLLAGLRDAARLRIAR--EMGIEAVV-DLAERPLDAALQTSFGGRCDRV 239
Query: 337 IDCTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIGVKINPFSFP 158
I+ TGV + LR G +V G ++ + +K+ P +F
Sbjct: 240 IEATGVAASVGQGLQALRPEGIFVAAGIHAAPCDLDLSRL-VREKKQLRGAHDTTPAAFA 298
Query: 157 NALGWLKAMGNRYVNYEKLGVKTYALSEYESALKDLRAGLVXKAM 23
A+ L+ G+ + L T LS E A R G K +
Sbjct: 299 EAISLLERRGDALAH---LITHTLPLSRGEEAFALARDGAAMKVL 340
>UniRef50_Q5WJ77 Cluster: Sorbitol dehydrogenase; n=1; Bacillus
clausii KSM-K16|Rep: Sorbitol dehydrogenase - Bacillus
clausii (strain KSM-K16)
Length = 346
Score = 82.6 bits (195), Expect = 1e-14
Identities = 63/246 (25%), Positives = 112/246 (45%), Gaps = 9/246 (3%)
Frame = -1
Query: 847 EFSGTITDVGKKSVFRN-GQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
E +G +T VG + N G VV++P C C CR G Y C S+ DG
Sbjct: 63 ECAGVVTKVGPEVADLNVGDHVVIEPGLPCGECSSCRVGHYNLCPKVLFLSSPP--NDGV 120
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
+Y+ P Y +P+G+S E L EP S + + S + G I+I+G G +G
Sbjct: 121 LMEYICHPAKFTYKMPEGLSFELASLAEPLSVGLYTAQKTS-IQPGSNIVIMGMGPVGLC 179
Query: 490 WVTSLHQLGHRDVTVSEMNKVRLEIVNK------LETGYRLVTPDVLEKEKQL--YDVII 335
+ + G ++ V+++ RLEI K ++ + +L + +L +D++I
Sbjct: 180 MILAAKWYGASNIVVTDIEPYRLEIAKKIGAMDTIQVNHEADRAGLLAEADRLGGFDMVI 239
Query: 334 DCTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIGVKINPFSFPN 155
D +G +++ N L+ GG G P +++I ++ +E+ + +F +
Sbjct: 240 DTSGAEAAFDMAVNLLKRGGTIGGIG-FPGGAKSTIPLLKMMQREIVYQPIYRYRHTFKH 298
Query: 154 ALGWLK 137
AL L+
Sbjct: 299 ALALLE 304
>UniRef50_Q5LVU9 Cluster: Sorbitol dehydrogenase, putative; n=13;
Alphaproteobacteria|Rep: Sorbitol dehydrogenase,
putative - Silicibacter pomeroyi
Length = 332
Score = 82.6 bits (195), Expect = 1e-14
Identities = 63/208 (30%), Positives = 93/208 (44%), Gaps = 2/208 (0%)
Frame = -1
Query: 802 RNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGGWAQYVKVPQDQVYLLP 623
R+G++V V+P C C CR+G+ C T I S R+GG+A+YV +P+ + +P
Sbjct: 70 RDGERVTVNPLVTCGACPACREGRDNLCPTRQIISMPP--REGGFAEYVAMPEGNLVTVP 127
Query: 622 DGVSTEQGGLCEPYSCVAHGYDRASPLLVG--EKILIVGAGIIGNLWVTSLHQLGHRDVT 449
D V Q L EP +C H + L G + L++G G IG L G VT
Sbjct: 128 DSVPLAQAALAEPLACGWHTVRLSLAALSGARDTALVLGGGAIGLGAALCLTAQGVPQVT 187
Query: 448 VSEMNKVRLEIVNKLETGYRLVTPDVLEKEKQLYDVIIDCTGVGKVMEISFNYLRHGGKY 269
V E N R ++ + L TP + YD++ID G + ++R GG
Sbjct: 188 VVEPNPARRAYLSDRCGQHALDTPPAGSQ----YDLVIDGVGYAATRATASAHVRPGGVI 243
Query: 268 VLFGCCPPTHQASINPFQIYDKELTIIG 185
G T I + +E+T IG
Sbjct: 244 GHIGLGEDTGGLDIRRMTL--QEITFIG 269
>UniRef50_A7F503 Cluster: Putative uncharacterized protein; n=1;
Sclerotinia sclerotiorum 1980|Rep: Putative
uncharacterized protein - Sclerotinia sclerotiorum 1980
Length = 420
Score = 82.6 bits (195), Expect = 1e-14
Identities = 67/246 (27%), Positives = 106/246 (43%), Gaps = 24/246 (9%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWR--D 677
E +G +T VG + + G V ++ C CD C G+Y C S+ +
Sbjct: 77 ESAGVVTAVGSEVKNLKVGDHVALEVGLPCKNCDLCASGRYNICKEMKFRSSAKAFPHFQ 136
Query: 676 GGWAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIG 497
G + + P +LLP VS E G + EP S HG RA+ L G+ +LI GAG +G
Sbjct: 137 GTLQERINHPAAYCHLLPSNVSLELGAVLEPLSVAIHGSRRAA-LPKGKTVLIFGAGAVG 195
Query: 496 NLWVTSLHQLGHRDVTVSEMNKVRLE--IVNKLETGYRLV--------------TPDVLE 365
L G +++ ++++ RL+ I NK LV +V E
Sbjct: 196 LLCAAMCRVTGAKNIVIADIQPDRLDFAIQNKFADAKLLVPMTRPQSIEDKLAFAKEVAE 255
Query: 364 KEKQL-----YDVIIDCTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKE 200
K+ D + +CTGV ++ S + GGK +L G P I+ + +E
Sbjct: 256 LVKEASGEGEVDAVFECTGVESCLQASIYSTKPGGKIMLIGMGTPIQTLPISAAAL--RE 313
Query: 199 LTIIGV 182
+ ++GV
Sbjct: 314 VDLVGV 319
>UniRef50_A7DRK1 Cluster: Alcohol dehydrogenase GroES domain
protein; n=1; Candidatus Nitrosopumilus maritimus
SCM1|Rep: Alcohol dehydrogenase GroES domain protein -
Candidatus Nitrosopumilus maritimus SCM1
Length = 321
Score = 82.6 bits (195), Expect = 1e-14
Identities = 57/261 (21%), Positives = 124/261 (47%), Gaps = 1/261 (0%)
Frame = -1
Query: 796 GQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIW-RDGGWAQYVKVPQDQVYLLPD 620
G++VV + N C+ CD C+KG ++C + +GI RDG +A+++ +P++ ++++PD
Sbjct: 75 GKRVVGEINAGCNRCDSCKKGLQRHCPN---RTVLGILKRDGAFAEFLSLPEENLHVIPD 131
Query: 619 GVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNLWVTSLHQLGHRDVTVSE 440
+S EQ EP + ++ S L K+ +VG G + + + + +L +VT
Sbjct: 132 SISDEQAVFVEPLAAAFEIKEQVS-LNPDWKVAVVGDGRLAQM-ICQVLKLSCPNVTCFG 189
Query: 439 MNKVRLEIVNKLETGYRLVTPDVLEKEKQLYDVIIDCTGVGKVMEISFNYLRHGGKYVLF 260
++ +L + K + ++ +++ + Q YD++++ TG + ++ G +L
Sbjct: 190 RHETKLSHLEKFKIQTKI---GIIDSDLQSYDLVVEATGSNSGFADTMKLVKPRGTVILK 246
Query: 259 GCCPPTHQASINPFQIYDKELTIIGVKINPFSFPNALGWLKAMGNRYVNYEKLGVKTYAL 80
+ P + E+T+IG + F P + A+ V+ + + T+ L
Sbjct: 247 STIASRENLDLTPTVV--NEITLIGSRCGLFK-PA----IDALATGIVSVDSMVYSTFPL 299
Query: 79 SEYESALKDLRAGLVXKAMFK 17
++ A++ + K K
Sbjct: 300 EKFSDAIQHAKKPDTLKVFLK 320
>UniRef50_P0A9S4 Cluster: Galactitol-1-phosphate 5-dehydrogenase;
n=27; cellular organisms|Rep: Galactitol-1-phosphate
5-dehydrogenase - Escherichia coli O157:H7
Length = 346
Score = 82.6 bits (195), Expect = 1e-14
Identities = 73/278 (26%), Positives = 119/278 (42%), Gaps = 12/278 (4%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
EFSG I VG G V P C C C KG Y C +G RDGG
Sbjct: 60 EFSGYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDF---IGSRRDGG 116
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
+A+Y+ V + V+ LP + E G EP + H + A + ++I+GAG IG L
Sbjct: 117 FAEYIVVKRKNVFALPTDMPIEDGAFIEPITVGLHAFHLAQG-CENKNVIIIGAGTIGLL 175
Query: 490 WVTSLHQLGHRDVTVSEMNKVRLEIVNK---LET--GYRLVTPDV--LEKEKQLYDVIID 332
+ LG + VT +++ +L + ++T + P + + +E + +I++
Sbjct: 176 AIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLILE 235
Query: 331 CTGVGKVMEISFNYLRHGGKYVLFGCC-PPTHQASINPFQIYDKELTIIGVKINPFSFPN 155
GV + +E++ + L G H S +I KELT+IG +N S
Sbjct: 236 TAGVPQTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTVIGSWMNYSSPWP 295
Query: 154 ALGWLKA---MGNRYVNYEKLGVKTYALSEYESALKDL 50
W A + R ++ E L + + A++D+
Sbjct: 296 GQEWETASRLLTERKLSLEPLIAHRGSFESFAQAVRDI 333
>UniRef50_Q2KCX6 Cluster: Probable zinc-type alcohol dehydrogenase
protein; n=2; Rhizobium|Rep: Probable zinc-type alcohol
dehydrogenase protein - Rhizobium etli (strain CFN 42 /
ATCC 51251)
Length = 339
Score = 82.2 bits (194), Expect = 1e-14
Identities = 64/228 (28%), Positives = 107/228 (46%), Gaps = 7/228 (3%)
Frame = -1
Query: 847 EFSGTITDVGKKSVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGGW 668
E S T+ + G+ G V+V+P +C C C KGK C + +G+ DG +
Sbjct: 61 EISATVIEAGEGVTLAAGTSVIVNPYLSCGQCVACIKGKPNCCTNIKV---LGVHTDGAF 117
Query: 667 AQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNLW 488
+ + VP +Y G+S E E + AH R S G + L++GAG IG L
Sbjct: 118 CEEISVPAGNLY-PAKGLSLEAAATTEFLAIGAHAV-RRSLTGAGARALVIGAGPIG-LG 174
Query: 487 VTSLHQLGHRDVTVSEMNKVRLEIVNK---LETGY--RLVTPDVLEKEK--QLYDVIIDC 329
++ DVT+ + + RL++ ++ +G T D + ++ +DV+ D
Sbjct: 175 AAIFSRIAGHDVTLLDTSAERLQMASERFGFTSGIVANEKTADAVREKTNGDGFDVVFDA 234
Query: 328 TGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIG 185
TG G ME +F ++ HGG VL + S +P + + +E+ +IG
Sbjct: 235 TGYGPSMEKAFAFVAHGGALVLVSVVKDDIRFS-DP-EFHKREMMLIG 280
>UniRef50_A6M074 Cluster: Alcohol dehydrogenase GroES domain
protein; n=1; Clostridium beijerinckii NCIMB 8052|Rep:
Alcohol dehydrogenase GroES domain protein - Clostridium
beijerinckii NCIMB 8052
Length = 349
Score = 82.2 bits (194), Expect = 1e-14
Identities = 73/283 (25%), Positives = 123/283 (43%), Gaps = 8/283 (2%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
E +G I +VG + + G +VV++P C C C+ + +C + G+ DG
Sbjct: 61 ESTGIIAEVGSEVKNVKVGDRVVINPTYYCGKCRMCQTLRINHCENK-FGTESGVSYDGT 119
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
+A + D VY +PDGVS + L EP SCV G + P + + GAG +G L
Sbjct: 120 YADRYRTTSDFVYKIPDGVSMKAVTLTEPLSCVITGARKIQPSSMNLNTYVFGAGTMGIL 179
Query: 490 WVTSLHQLGHRDVTV-SEMNKVRL------EIVNKLETGYRLVTPDVLEKEKQLYDVIID 332
+ +LH G V + + +N++ + VN + + + K D+++D
Sbjct: 180 YTWALHLKGLTPVVIETSLNRLNYASDCVPQGVN-IYSSLEEARTNYFNDPKAPLDIVVD 238
Query: 331 CTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIGVKINPFSFPNA 152
T ++E + + G Y+ G A+IN ++ DK L+IIG I+ +
Sbjct: 239 TT--SGLLEKLYPEMSCDGTYMSIGL--KDKYANINVRELADKSLSIIG-SIDSL-HGSF 292
Query: 151 LGWLKAMGNRYVNYEKLGVKTYALSEYESALKDLRAGLVXKAM 23
L + + EKL L Y+ A L + K+M
Sbjct: 293 LDAFHLITKNIIPAEKLVSHVIPLENYKKAFSILGCDIDSKSM 335
>UniRef50_Q9RTU4 Cluster: L-threonine 3-dehydrogenase; n=178;
Bacteria|Rep: L-threonine 3-dehydrogenase - Deinococcus
radiodurans
Length = 348
Score = 82.2 bits (194), Expect = 1e-14
Identities = 61/231 (26%), Positives = 107/231 (46%), Gaps = 9/231 (3%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
E+ G + +G + F G +V + + C C CR G+ C VG+ R G
Sbjct: 64 EYVGVVAGMGSEVRGFEIGDRVSGEGHVTCGHCRNCRAGRRHLCRNT---QGVGVNRPGS 120
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
+A+Y+ +P + LPD + + + +P+ H S LVGE +LI GAG IG +
Sbjct: 121 FAEYLVLPAFNAFKLPDDIPDDVAAIFDPFGNAVH--TALSFDLVGEDVLITGAGPIGCM 178
Query: 490 WVTSLHQLGHRDVTVSEMNKVRLEIVNKL--ETGYRLVTPD---VLEKEKQL---YDVII 335
+G R+V ++++N RL++ ++ + D V +E + +DV +
Sbjct: 179 AAAVARHVGARNVVITDVNDYRLDLARQMGVTRAVNVAREDLWTVATQELDMHEGFDVGM 238
Query: 334 DCTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIGV 182
+ +G G + + +GGK L G P+ + I+ + K LTI G+
Sbjct: 239 EMSGSGPAFAQMVSVMNNGGKVALLGI--PSGEVQIDWNAVIFKMLTIKGI 287
>UniRef50_Q9KGB7 Cluster: Sorbitol dehydrogenase; n=28;
Bacillales|Rep: Sorbitol dehydrogenase - Bacillus
halodurans
Length = 354
Score = 81.8 bits (193), Expect = 2e-14
Identities = 58/205 (28%), Positives = 93/205 (45%), Gaps = 8/205 (3%)
Frame = -1
Query: 847 EFSGTITDVGKKSV-FRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
EF+G + +G+ F G +V P C C +C+ G+ C S +G G
Sbjct: 60 EFAGEVVKIGRSVTGFSIGDRVAACPTYTCGQCRYCQLGEPTRCERL---SVIGARHPGA 116
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
+A+YVK+P V LP+ V+ ++ L EP S VAHG+ R + + G + I+G G IG L
Sbjct: 117 YAEYVKLPAKHVIPLPNVVNYDEAALIEPASVVAHGFYRTN-IKPGASVAIMGVGSIGLL 175
Query: 490 WVTSLHQLGHRDVTVSEMNKVRLEIVNKL------ETGYRLVTPDVLEKEKQL-YDVIID 332
V G V ++++ +L + N+L + R +LE + DV ++
Sbjct: 176 AVQWAKIFGATTVFAIDIDEQKLNVANQLGADVLISSLQRPAHKQILEYTNGIGVDVAVE 235
Query: 331 CTGVGKVMEISFNYLRHGGKYVLFG 257
G F + GG+ V G
Sbjct: 236 SAGTPSTSAQVFALPKKGGEVVFLG 260
>UniRef50_Q00796 Cluster: Sorbitol dehydrogenase; n=35;
Eumetazoa|Rep: Sorbitol dehydrogenase - Homo sapiens
(Human)
Length = 357
Score = 81.8 bits (193), Expect = 2e-14
Identities = 78/287 (27%), Positives = 125/287 (43%), Gaps = 10/287 (3%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
E SGT+ VG + G +V ++P +FC+ G+Y L+ I DG
Sbjct: 71 EASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYN--LSPSIFFCATPPDDGN 128
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
++ K Y LPD V+ E+G L EP S H R + +G K+L+ GAG IG +
Sbjct: 129 LCRFYKHNAAFCYKLPDNVTFEEGALIEPLSVGIHACRRGG-VTLGHKVLVCGAGPIGMV 187
Query: 490 WVTSLHQLGHRDVTVSEMNKVRL----EIVNKLETGYRLVTP-DVLEKEKQLY----DVI 338
+ +G V V++++ RL EI L +P ++ K + L +V
Sbjct: 188 TLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGLLGCKPEVT 247
Query: 337 IDCTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIGVKINPFSFP 158
I+CTG ++ R GG VL G + ++ +E+ I GV ++P
Sbjct: 248 IECTGAEASIQAGIYATRSGGTLVLVGL--GSEMTTVPLLHAAIREVDIKGVFRYCNTWP 305
Query: 157 NALGWLKAMGNRYVNYEKLGVKTYALSEYESALKDLRAGLVXKAMFK 17
A+ L ++ VN + L + L + A + + GL K M K
Sbjct: 306 VAISML---ASKSVNVKPLVTHRFPLEKALEAFETFKKGLGLKIMLK 349
>UniRef50_A5I7E3 Cluster: Sorbitol dehydrogenase; n=7;
Clostridium|Rep: Sorbitol dehydrogenase - Clostridium
botulinum A str. ATCC 3502
Length = 349
Score = 81.4 bits (192), Expect = 3e-14
Identities = 60/229 (26%), Positives = 106/229 (46%), Gaps = 8/229 (3%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
EFSG + ++G + G+++ V P C C+FC+KG + C T +G DGG
Sbjct: 63 EFSGEVVEIGNNVDDIKVGERIAVAPLIPCGECEFCKKGNFALCETYEF---LGSRNDGG 119
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
+A+YV+VP++ V +LP+ + E EP S +++ + + VG+ + +VG G IG
Sbjct: 120 FAEYVRVPKENVLILPEDLDYETAAGIEPAS-ISYQAMSKTGIKVGDTVAVVGCGPIGQF 178
Query: 490 WVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLVTPDVLEKEKQL------YDVIIDC 329
+ G V ++ + +L + +L + + + EK L + +++
Sbjct: 179 AIQWAKIFGASKVIAVDVLEDKLNLAKELGADIIINSKECNAVEKVLEITNGGVEAVVET 238
Query: 328 TGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPF-QIYDKELTIIG 185
G+ E S R GK V G + S F +I E+T+ G
Sbjct: 239 AGMKITEEQSVLMCRKLGKVVFLGISHDELRFSEKTFDRIMRGEITLQG 287
>UniRef50_A0GHL5 Cluster: Alcohol dehydrogenase GroES-like; n=1;
Burkholderia phytofirmans PsJN|Rep: Alcohol
dehydrogenase GroES-like - Burkholderia phytofirmans
PsJN
Length = 348
Score = 81.4 bits (192), Expect = 3e-14
Identities = 55/211 (26%), Positives = 97/211 (45%), Gaps = 7/211 (3%)
Frame = -1
Query: 796 GQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIW--RDGGWAQYVKVPQDQVYLLP 623
GQ+V V+P AC C FC G +CL + + G + QY+ V Q +P
Sbjct: 84 GQRVAVNPGLACGTCRFCVGGMPNHCLNMRFMGSASTFPHTQGMFRQYIVVAARQCVPVP 143
Query: 622 DGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNLWVTSLHQLGHRDVTVS 443
DGV Q + EP + H +A LVG +L+VG G IG + ++ + G V
Sbjct: 144 DGVDFAQASMAEPLAVALHAVKQAGS-LVGASVLLVGCGPIGCILLSVARRAGAHRVVAL 202
Query: 442 EMNKVRLEIVNKLETGYRLVTPD--VLEK---EKQLYDVIIDCTGVGKVMEISFNYLRHG 278
+++ L++ +L + + V+++ ++ +DV+I+ +G ++ + + R G
Sbjct: 203 DLSDRALQVARQLGADQTVNAAERAVIDQWSVQRGTFDVVIEASGSPAGLDTALHAARAG 262
Query: 277 GKYVLFGCCPPTHQASINPFQIYDKELTIIG 185
G + G P Q+ + + KEL G
Sbjct: 263 GTVIQVGNL-PAGQSPVAANLVMSKELRYQG 292
>UniRef50_O58389 Cluster: Probable L-threonine 3-dehydrogenase; n=7;
cellular organisms|Rep: Probable L-threonine
3-dehydrogenase - Pyrococcus horikoshii
Length = 348
Score = 81.4 bits (192), Expect = 3e-14
Identities = 74/288 (25%), Positives = 122/288 (42%), Gaps = 10/288 (3%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
E +G + ++G G V V+ + C C CR+G+Y C I G+ DG
Sbjct: 68 EVAGEVVEIGPGVEGIEVGDYVSVETHIVCGKCYACRRGQYHVCQNTKI---FGVDTDGV 124
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
+A+Y VP ++ P + E L EP A P+ G+ +LI GAG +G L
Sbjct: 125 FAEYAVVPAQNIWKNPKSIPPEYATLQEPLGNAVDTV-LAGPIS-GKSVLITGAGPLGLL 182
Query: 490 WVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLVTP---DVLEKEKQL-----YDVII 335
+ G V VSE + R E+ K+ Y ++ P DV+++ + DV +
Sbjct: 183 GIAVAKASGAYPVIVSEPSDFRRELAKKVGADY-VINPFEEDVVKEVMDITDGNGVDVFL 241
Query: 334 DCTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIGVKINPFSFPN 155
+ +G K +E + G+ L G P N I+ K LTI G+ +
Sbjct: 242 EFSGAPKALEQGLQAVTPAGRVSLLGLYPGKVTIDFNNLIIF-KALTIYGI-TGRHLWET 299
Query: 154 ALGWLKAMGNRYVNYEKLGVKTY-ALSEYESALKDLRAGLVXKAMFKI 14
+ + + +N + + Y +YE A + +RAG K +F +
Sbjct: 300 WYTVSRLLQSGKLNLDPIITHKYKGFDKYEEAFELMRAGKTGKVVFML 347
>UniRef50_O35045 Cluster: Zinc-containing alcohol dehydrogenase;
n=5; Bacillus|Rep: Zinc-containing alcohol dehydrogenase
- Bacillus subtilis
Length = 339
Score = 81.0 bits (191), Expect = 3e-14
Identities = 70/275 (25%), Positives = 122/275 (44%), Gaps = 8/275 (2%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
E +G + VG + G VV++P C C CRKG+ C S G+ DGG
Sbjct: 61 EVTGQVEAVGANVQSLKPGDHVVIEPISYCGSCYACRKGRPNVCAKL---SVFGVHEDGG 117
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
+Y+ +P+ Q++ + + E+ + EPY+ A R + G+ +LI GAG IG +
Sbjct: 118 MREYIVLPERQLHAVSKDLPWEEAVMAEPYTIGAQAVWRGQ-VEKGDTVLIQGAGPIG-I 175
Query: 490 WVTSLHQLGHRDVTVSEMNKVRLEIVNK------LETGYRLVTPDVLE-KEKQLYDVIID 332
V + +L V ++++N RL + + V VLE + +V+ID
Sbjct: 176 CVLKMAKLAGAAVMMTDLNNERLAFAKENGADAVVNVQAEHVAERVLEWTGNEGANVVID 235
Query: 331 CTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIGVKINPFSFPNA 152
+ + +S + G V+ G A I+ I KE+TI G ++ FP
Sbjct: 236 AVCLPETFALSIEAVSPAGHVVVLGF--DERAAQISQLPITKKEVTITGSRLQTNQFPKV 293
Query: 151 LGWLKAMGNRYVNYEKLGVKTYALSEYESALKDLR 47
+ L G R + + L T+++ + A + ++
Sbjct: 294 VELLN--GGRLM-HNGLVTHTFSVDDVHHAFQFIK 325
>UniRef50_Q5KPJ4 Cluster: Sorbitol dehydrogenase, putative; n=1;
Filobasidiella neoformans|Rep: Sorbitol dehydrogenase,
putative - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 416
Score = 81.0 bits (191), Expect = 3e-14
Identities = 78/274 (28%), Positives = 116/274 (42%), Gaps = 27/274 (9%)
Frame = -1
Query: 796 GQKVVVDPNRACSLCDFCRKGKYQYC---LTAGINSTVGIWRDGGWAQYVKVPQDQVYLL 626
G KV ++P C +C C+ GKYQ C + A + G G +Y +P D VY L
Sbjct: 130 GDKVALEPGVTCRMCVDCKGGKYQICEHMIFAAYPPSTG----GTLQRYYALPADLVYPL 185
Query: 625 PDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNLWVTSLHQLGHRDVTV 446
PD V G + EP S H + G +LI GAG +G L + LG V
Sbjct: 186 PDNVDLSFGAMMEPLSVATHAVANIGGMRTGWNVLITGAGPVGLLAMAVAKGLGAGKVIA 245
Query: 445 SEMNKVRLEIVNKLET--GYRLVTPD---------VLEKEKQL------------YDVII 335
++N+ RL + Y + P+ V E L D+++
Sbjct: 246 VDINEERLHFAKQYAATDTYIPIPPNEGESRGDHAVRAAEDLLRSTGTPARGPGSIDLVV 305
Query: 334 DCTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIGV-KINPFSFP 158
D TG + + N ++ GG YV G PP S+ F+I E+TI G + +P
Sbjct: 306 DATGAETCVLMGLNAIKPGGIYVQIGFGPP--NVSVPMFRIVTNEITIRGAWRYGSGDYP 363
Query: 157 NALGWLKAMGNRYVNYEKLGVKTYALSEYESALK 56
A+ + A G VN + L T+ ++E AL+
Sbjct: 364 LAID-MVARG--LVNLKPLLTHTF---KFEDALE 391
>UniRef50_Q3B3S5 Cluster: Alcohol dehydrogenase, zinc-containing;
n=1; Pelodictyon luteolum DSM 273|Rep: Alcohol
dehydrogenase, zinc-containing - Pelodictyon luteolum
(strain DSM 273) (Chlorobium luteolum (strain DSM273))
Length = 323
Score = 80.6 bits (190), Expect = 5e-14
Identities = 51/179 (28%), Positives = 82/179 (45%)
Frame = -1
Query: 796 GQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGGWAQYVKVPQDQVYLLPDG 617
GQ + P +AC C CR G+ C I G RDGG+A+++ P+ + +P+G
Sbjct: 70 GQLYALWPGQACGSCMACRSGRQNLCPDMRIT---GFHRDGGFAEFLTAPRSSLLEVPEG 126
Query: 616 VSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNLWVTSLHQLGHRDVTVSEM 437
V L EP +C HG R + E++LI GAG +G L + G V +S+
Sbjct: 127 VGPVMATLAEPLACAVHGV-RQGGVSSRERVLIYGAGTLGLLVALVARECG-ASVVMSDP 184
Query: 436 NKVRLEIVNKLETGYRLVTPDVLEKEKQLYDVIIDCTGVGKVMEISFNYLRHGGKYVLF 260
+ +L + + T L+DV+ + T + +E + L GG++ LF
Sbjct: 185 DIEKLSKSEVFRNRFGIGTDVHPGAPCGLFDVVFNATPAPEAIEAGVDRLAAGGRFCLF 243
>UniRef50_Q0TT56 Cluster: L-iditol 2-dehydrogenase; n=3;
Clostridiaceae|Rep: L-iditol 2-dehydrogenase -
Clostridium perfringens (strain ATCC 13124 / NCTC 8237 /
Type A)
Length = 348
Score = 80.6 bits (190), Expect = 5e-14
Identities = 60/226 (26%), Positives = 109/226 (48%), Gaps = 8/226 (3%)
Frame = -1
Query: 847 EFSGTITDVGKKSVFRN-GQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
E G + +VG K N G +V ++P + C C+FC+ G+Y C +T + DG
Sbjct: 67 EPGGVVVEVGNKVKHLNIGDRVALEPGKTCGHCEFCKTGRYNLCPDVIFFATPPV--DGV 124
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
+ +YV D + LP+ VST +G L EP + H + +G+ +++GAG IG +
Sbjct: 125 FQEYVAHEADLCFKLPENVSTLEGALIEPLAVGFHAAIQGG-ARIGQTAVVMGAGCIGLV 183
Query: 490 WVTSLHQLGHRDVTVSEMNKVRLEIVNKL-ETG-YRLVTPDVLEKEKQL-----YDVIID 332
+ +L +G +V + ++ + RLE +L TG + +E+ ++ D++I+
Sbjct: 184 SMMALKAMGVSNVYIVDIMEKRLEKALELGATGIINAKEKNAIEEVMKITNNNGCDLVIE 243
Query: 331 CTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELT 194
G + + + G VL G + + ++ + DKELT
Sbjct: 244 TAGTEITTVQAIHMAKKGSNIVLVG-YSKSGEMTLPMSLVLDKELT 288
>UniRef50_Q65L05 Cluster: YjmD; n=1; Bacillus licheniformis ATCC
14580|Rep: YjmD - Bacillus licheniformis (strain DSM 13
/ ATCC 14580)
Length = 338
Score = 79.8 bits (188), Expect = 8e-14
Identities = 68/248 (27%), Positives = 114/248 (45%), Gaps = 12/248 (4%)
Frame = -1
Query: 847 EFSGTITDVGKKSVFRN-GQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
E +G I G R+ G++VV++P C C CRKG+ C+ + +G R GG
Sbjct: 60 ELAGIIEKTGAGVRGRSAGERVVIEPAIPCGGCYPCRKGRTNACMNIDM---IGSVRRGG 116
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
+A ++ VP+ V+ +P+ + LCEP+S A RA + GE I+I+G G IG
Sbjct: 117 FADFIIVPETHVHPIPEQMDFATAALCEPFSIGAQAVRRAD-IQTGETIVILGMGPIG-- 173
Query: 490 WVTSLHQLGHR-DVTVSEMNKV--RLEIVNKLETGYRLVTPDVLEKEKQLY--------D 344
+T L Q+ R DV V ++ V RLE+ ++ P + E+ +
Sbjct: 174 -LTILAQVKKRFDVRVIAVDPVRERLELAEAFGAD-AVIQPGEEDAEQMILKLTGGEGAG 231
Query: 343 VIIDCTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIGVKINPFS 164
++ + G+ +E S G+ V+ G +I + K++ I G K +
Sbjct: 232 IVFEAAGIPATIEQSVRLAAAAGRIVIVGL--TGRNVTIPGLLLTKKDIEIYGTKHSVNQ 289
Query: 163 FPNALGWL 140
FP + +L
Sbjct: 290 FPGVIQFL 297
>UniRef50_Q3WCL0 Cluster: Zinc-containing alcohol dehydrogenase
superfamily; n=6; Actinomycetales|Rep: Zinc-containing
alcohol dehydrogenase superfamily - Frankia sp. EAN1pec
Length = 347
Score = 79.8 bits (188), Expect = 8e-14
Identities = 57/200 (28%), Positives = 93/200 (46%), Gaps = 3/200 (1%)
Frame = -1
Query: 847 EFSGTITDVGKKS-VFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
E+SGT+ VG G+ VV + R+C +C CR+G C TA + T G G
Sbjct: 64 EWSGTVAAVGPAGDAALVGRPVVAEGFRSCRVCPACRRGDTNLC-TAPYDET-GFTCPGA 121
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
W+ ++ VP +++LP G EP +C A RA + GE++ +VGAG +G L
Sbjct: 122 WSDHLVVPSHLLHVLPAGADLRAAAGLEPAACAAAMCLRAG-AVPGERVAVVGAGTLGLL 180
Query: 490 WVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLVTPDVLE--KEKQLYDVIIDCTGVG 317
L G ++ + R E+ + L++PD + + +DV+++ G
Sbjct: 181 ATQLLAAGGPAELVAVDPRAGRAELAARC-GATTLLSPDEAAGGRWSRRFDVVVEAAGAP 239
Query: 316 KVMEISFNYLRHGGKYVLFG 257
++ R GG+ VL G
Sbjct: 240 GSAALACGLARRGGRVVLAG 259
>UniRef50_Q1QWS0 Cluster: Alcohol dehydrogenase GroES-like protein;
n=1; Chromohalobacter salexigens DSM 3043|Rep: Alcohol
dehydrogenase GroES-like protein - Chromohalobacter
salexigens (strain DSM 3043 / ATCC BAA-138 / NCIMB13768)
Length = 349
Score = 79.8 bits (188), Expect = 8e-14
Identities = 69/230 (30%), Positives = 100/230 (43%), Gaps = 9/230 (3%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
E SG I VG+ G V P C C CR+GK C + +G+ RDGG
Sbjct: 60 ELSGDIVGVGEGVDESLVGHSAYVIPYLHCGECRACRQGKTNCCQHMQV---IGVHRDGG 116
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
A+Y+ VP D + + + EQ L E S AH R S + E ++VGAG IG +
Sbjct: 117 MAEYLSVPVDHL-VTSSTLDAEQLALVECLSIGAHAV-RRSAIEADELAVVVGAGPIG-I 173
Query: 490 WVTSLHQLGHRDVTVSEMNKVRLEIVNK---LETGYRLVTPDV-----LEKEKQLYDVII 335
+ + Q V V + N+ RL +E + DV + L DV+
Sbjct: 174 GIVQIAQSRGARVLVVDTNRERLAFCRDTLGVEDVLHALDDDVEAAIARHHDGALADVVF 233
Query: 334 DCTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIG 185
D TG M F++ HGG+YVL + N + +EL+++G
Sbjct: 234 DATGNPAAMNRGFDFAGHGGRYVLVSVVKA--DITFNDPDFHKRELSLLG 281
>UniRef50_Q8DK96 Cluster: Tll0970 protein; n=6; Cyanobacteria|Rep:
Tll0970 protein - Synechococcus elongatus
(Thermosynechococcus elongatus)
Length = 373
Score = 79.0 bits (186), Expect = 1e-13
Identities = 80/293 (27%), Positives = 134/293 (45%), Gaps = 20/293 (6%)
Frame = -1
Query: 847 EFSGTITDVGKKSV-FRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
E +G I +G ++ G +VV + + C C +C++ + C N+ G
Sbjct: 86 EAAGEIVALGAGVTGWQVGDRVVANNSAPCGQCFYCQRQAFSLCPHLEFNN-------GT 138
Query: 670 WAQYVKVP----QDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRAS--PLLVGE-----KI 524
+A+Y+K+P + + +P+ + L EP +CV HG R+ P +V +I
Sbjct: 139 FAEYLKLPASIVRQNLLPIPESLPFALAALTEPLACVLHGVARSGFDPAMVATWPSPPQI 198
Query: 523 LIVGAGIIGNLWVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLV------TPDVLEK 362
+++G G IG ++V L Q G R + N+ RL I + P V++
Sbjct: 199 VVLGDGAIGLMFVGVLAQQGARVLAFGGSNQ-RLAIATTFGAEQTINHHQCGDIPAVVKD 257
Query: 361 --EKQLYDVIIDCTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTII 188
E + D++I+ TGV +V E + R G LFG CP ++ +++ +ELT+
Sbjct: 258 WTEGRGADIVIEATGVPEVWETAIACGRPGATINLFGGCPRETTIRVDTERLHYEELTLK 317
Query: 187 GVKINPFSFPNALGWLKAMGNRYVNYEKLGVKTYALSEYESALKDLRAGLVXK 29
GV N SF L A G + +EKL L E E+ L+ ++A V K
Sbjct: 318 GVFHNTPSFVRQALQLIASGT--LPFEKLISGQAPLMEIETVLQAMKARQVIK 368
>UniRef50_Q2G759 Cluster: GroES-related; n=1; Novosphingobium
aromaticivorans DSM 12444|Rep: GroES-related -
Novosphingobium aromaticivorans (strain DSM 12444)
Length = 335
Score = 79.0 bits (186), Expect = 1e-13
Identities = 58/228 (25%), Positives = 101/228 (44%), Gaps = 8/228 (3%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
EF+G + +GK R G V V P ++C C CR G+ Q+C G+ + GG
Sbjct: 61 EFAGEVVALGKGVEGLRTGDLVSVIPLQSCGQCHSCRTGEVQWCERFGL-------QGGG 113
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
+A++ +Q LP S G + EP + HG S + +G+K+L++GAG IG
Sbjct: 114 YAEFALTRPNQCVRLPASASMADGAIVEPLAVALHGL-ALSRMKIGDKVLVLGAGPIGLA 172
Query: 490 WVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLVTPDVLEKEKQL-------YDVIID 332
+ G V V ++ + + + L+ G D + D++ +
Sbjct: 173 VAFWARRFGAGRVVVQDLAEWQRD--RALQMGAHDFVVDAADPVGSAGRALGGKADIVFE 230
Query: 331 CTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTII 188
C GV ++ + +R+ G L G C T + N F + K++ ++
Sbjct: 231 CVGVPGLIAQAVEQVRNDGTITLLGLC--TRPDTFNSFAMLSKQVKLV 276
>UniRef50_A0JVX4 Cluster: Alcohol dehydrogenase GroES domain
protein; n=1; Arthrobacter sp. FB24|Rep: Alcohol
dehydrogenase GroES domain protein - Arthrobacter sp.
(strain FB24)
Length = 349
Score = 78.6 bits (185), Expect = 2e-13
Identities = 80/290 (27%), Positives = 123/290 (42%), Gaps = 15/290 (5%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
EF+G I + G + S + G +V V PN C C C G C + GI DGG
Sbjct: 62 EFAGEIVEAGSEVSGYAVGDRVSVTPNVGCGTCPNCLVGLNNMCPSY---EAFGITMDGG 118
Query: 670 WAQYVKVP-----QDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLV--GEKILIVG 512
+ +YV++P + V+ LP+ V + L EP SC Y+ S L V +LI+G
Sbjct: 119 FQEYVRIPRFALNRGNVFHLPETVGYAEAALVEPLSCC---YNAVSKLDVRPDSTVLIMG 175
Query: 511 AGIIGNLWVTSLHQLGHRDVTVSEMNKVRLEIVNKL--ETGYRLVTPD----VLEKEKQL 350
AG IG V G R V VS + RL+ L + L D V E+ L
Sbjct: 176 AGPIGACHVMLAKLYGARKVIVSNNRQPRLDFAGTLGADVLVNLTERDLATVVAEETGGL 235
Query: 349 -YDVIIDCTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIGVKIN 173
DV + C +V + + L G+ F +++ +++ + LT+ G
Sbjct: 236 GVDVALTCVSKPEVQAQAVDLLATHGRVNFFAGLGKAQPVALDTNRVHYQGLTLTGT--T 293
Query: 172 PFSFPNALGWLKAMGNRYVNYEKLGVKTYALSEYESALKDLRAGLVXKAM 23
S + L +G ++ L +T+ L + E A+ +G KAM
Sbjct: 294 GSSNSDYASALSLVGEGRLDLSPLISQTFTLDDIEKAMDYAGSGQGMKAM 343
>UniRef50_A0JVW4 Cluster: Alcohol dehydrogenase GroES domain
protein; n=2; Arthrobacter|Rep: Alcohol dehydrogenase
GroES domain protein - Arthrobacter sp. (strain FB24)
Length = 343
Score = 78.6 bits (185), Expect = 2e-13
Identities = 72/273 (26%), Positives = 112/273 (41%), Gaps = 5/273 (1%)
Frame = -1
Query: 847 EFSGTITDVGKKSVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGGW 668
E +G + + G + G +V V+P C C C KG C + +GI G
Sbjct: 70 EITGILEEPGGSGI-PAGTRVAVNPLLPCGQCGACLKGLGHVCRNLRL---LGIDVPGSM 125
Query: 667 AQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNLW 488
+ + VP ++ + L EP + H R S L GEK+LI GAG IG L
Sbjct: 126 TEVLAVPVSNLFAFSADAPATEAALAEPLAVAVHAV-RRSRLAPGEKVLIFGAGPIGILV 184
Query: 487 VTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLVTPD----VLEKEKQLYDVIIDCTGV 320
G +DV + E ++ R IV L G+R + P E + DV+ DC G
Sbjct: 185 ALVARFRGAKDVLLVEPSEQRRHIVEAL--GFRALAPQDSPVARENREATADVVFDCAGH 242
Query: 319 GKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIGVKI-NPFSFPNALGW 143
V G+ V+ A+I+ ++ E IIGV++ P F +
Sbjct: 243 SSVTPALTEAAPVRGRIVIVAV--HHGPANIDLRELAFAEQEIIGVRVYEPADFAES--- 297
Query: 142 LKAMGNRYVNYEKLGVKTYALSEYESALKDLRA 44
++ +GNR + + + Y L A + R+
Sbjct: 298 VQLIGNRALGLAGVPISEYPLEAVADAFAEARS 330
>UniRef50_Q57517 Cluster: Uncharacterized zinc-type alcohol
dehydrogenase-like protein HI0053; n=18;
Gammaproteobacteria|Rep: Uncharacterized zinc-type
alcohol dehydrogenase-like protein HI0053 - Haemophilus
influenzae
Length = 342
Score = 78.6 bits (185), Expect = 2e-13
Identities = 69/266 (25%), Positives = 116/266 (43%), Gaps = 8/266 (3%)
Frame = -1
Query: 823 VGKKSVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGGWAQYVKVPQ 644
+G R G +V+VDP C C C G+ C + + +G+ DGG + ++ P
Sbjct: 74 IGMSDGVRVGDRVIVDPYVCCGQCYPCSIGRTNCCESLKV---IGVHIDGGMQEVIRHPA 130
Query: 643 DQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNLWVTSLHQLG 464
+ +PD + Q L EP + H R + L GE I+I+GAG IG + + Q G
Sbjct: 131 HLLTKVPDNLPIHQLPLAEPLTIALHALHRTT-LKSGEHIVIIGAGAIGLMAALAAVQYG 189
Query: 463 HRDVTVSEMNKVRLEIVNKLETGYRLVTP---DVLEKEKQ-----LYDVIIDCTGVGKVM 308
+ V + + RLE L + +V P D +++ K+ + +V+++ +G +
Sbjct: 190 AIPILVDILEQ-RLEYAKSLGIEH-IVNPHKEDDIKRIKEITSGRMAEVVMEASGANISI 247
Query: 307 EISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIGVKINPFSFPNALGWLKAMG 128
+ + +Y G+ L G P + + I KEL I G + + F AL L
Sbjct: 248 KNTLHYASFAGRIALTGW--PKTETPLPTNLITFKELNIYGSRTSKGEFEEALDML---A 302
Query: 127 NRYVNYEKLGVKTYALSEYESALKDL 50
+N + K E S + DL
Sbjct: 303 TNKINASHIITKCIKFEEIPSFISDL 328
>UniRef50_Q89F70 Cluster: L-idonate 5-dehydrogenase; n=1;
Bradyrhizobium japonicum|Rep: L-idonate 5-dehydrogenase
- Bradyrhizobium japonicum
Length = 349
Score = 78.2 bits (184), Expect = 2e-13
Identities = 57/208 (27%), Positives = 92/208 (44%), Gaps = 8/208 (3%)
Frame = -1
Query: 847 EFSGTITDV-GKKSVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIW--RD 677
E SG + ++ G + + G +V V+P+R C C CR+G+ C +
Sbjct: 67 EISGEVVEISGSAANLKVGDRVAVNPSRWCGHCVACREGRPNLCENIYFMGSASKTPHMQ 126
Query: 676 GGWAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIG 497
GG+A Y Q +PD VS + L EP + H RA + G++ +I GAG IG
Sbjct: 127 GGFANYFDAIPAQCVKIPDHVSYQAAALAEPLAVCLHAVARAGNI-EGKRGIIFGAGPIG 185
Query: 496 NLWVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLVTPDVLEKEK-----QLYDVIID 332
L + + H+ G D+TV+++ L ++L + E K + YDV +
Sbjct: 186 LLTMLAAHRAGMADITVADIAPAPLAFASRLGASHVENVSGGEEGLKAQAAARPYDVAFE 245
Query: 331 CTGVGKVMEISFNYLRHGGKYVLFGCCP 248
+G + + +R GG V G P
Sbjct: 246 VSGTAAGLASAIGIVRRGGVVVQIGNLP 273
>UniRef50_Q2RG84 Cluster: Alcohol dehydrogenase superfamily,
zinc-containing; n=1; Moorella thermoacetica ATCC
39073|Rep: Alcohol dehydrogenase superfamily,
zinc-containing - Moorella thermoacetica (strain ATCC
39073)
Length = 358
Score = 78.2 bits (184), Expect = 2e-13
Identities = 49/208 (23%), Positives = 92/208 (44%), Gaps = 13/208 (6%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGI----NSTVGIW 683
E++GTI +G+ F+ G +V ++ ++ C C+ C GKY CL G + G+
Sbjct: 70 EWAGTIVALGETVDEFQVGDRVAIEAHKGCGRCENCIDGKYTACLNYGRLDKGHRAAGMT 129
Query: 682 RDGGWAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGI 503
DGG+A+Y + VY +PD ++ + C + D++ + G+ +L++G G
Sbjct: 130 VDGGFAEYAVQHVNSVYKIPDNITFNEATYVTTAGCALYAIDKSGGYIAGDTVLVIGPGP 189
Query: 502 IGNLWVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLVTPDVLEKEKQLYDV------ 341
IG V LG + + + RL +L + + +V + ++ +
Sbjct: 190 IGLSVVQGARSLGAEKIILMGTREDRLVKGRELGATHTINIREVADPVAEVMAITGGKGC 249
Query: 340 --IIDCTGVGKVMEISFNYLRHGGKYVL 263
+ +C G + E + GG VL
Sbjct: 250 ERVFECAGNSQSFEYGIKAAKKGGVMVL 277
>UniRef50_Q188T6 Cluster: Putative sugar-phosphate dehydrogenase;
n=2; Clostridium difficile|Rep: Putative sugar-phosphate
dehydrogenase - Clostridium difficile (strain 630)
Length = 350
Score = 77.8 bits (183), Expect = 3e-13
Identities = 74/272 (27%), Positives = 114/272 (41%), Gaps = 14/272 (5%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGI--NSTVGIWRD 677
EFSG + VGK+ F+ G +V V P C CD C+KG Y C I N +G
Sbjct: 60 EFSGEVAQVGKEVRSFKIGDRVAVCPAMPCFECDECKKGLYSRCNNVAIIGNKELG---- 115
Query: 676 GGWAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIG 497
G +A+Y KV + + +PD +S E EP HG R S VG+ ++++G G IG
Sbjct: 116 GCFAEYTKVKERNLIKIPDEISYETAAALEPVCIAGHGLFR-SEAKVGDTVVVLGTGPIG 174
Query: 496 NLWVTSLHQLGHRDVTVSEMNKVRLEIVNKL--ETGYRLVTPDVLEKEKQL-----YDVI 338
+ G + ++ +L++ +L + +++E+ K+L D++
Sbjct: 175 LFSIQWAKIFGSTKIIAVDVFDEKLDLAKELGADICINAKEKNIVEEIKRLTDGDGADIV 234
Query: 337 IDCTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQ-IYDKELTIIGVKI-NPFS 164
I+ G + GG + G + F+ I ELT+ G N F
Sbjct: 235 IESAGTPLTCGQVLLLAKKGGTVLYAGVPYGDVALTREQFEKIVRSELTVKGTWFGNSFP 294
Query: 163 FPNA--LGWLKAMGNRYVNYEKLGVKTYALSE 74
FP L M +N EKL L E
Sbjct: 295 FPGKEWSAGLYHMQKGDMNVEKLVTHRINLEE 326
>UniRef50_A3U1C0 Cluster: Threonine 3-dehydrogenase; n=1; Oceanicola
batsensis HTCC2597|Rep: Threonine 3-dehydrogenase -
Oceanicola batsensis HTCC2597
Length = 349
Score = 77.8 bits (183), Expect = 3e-13
Identities = 55/204 (26%), Positives = 91/204 (44%), Gaps = 7/204 (3%)
Frame = -1
Query: 847 EFSGTITDVGKKSV-FRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
EF+G I G G +V + P+ C C C G+ + C +T+G++RDG
Sbjct: 66 EFAGIIEATGPGVARVTPGDRVTIWPSSPCDTCPECTAGRRRNCRN---KATLGLYRDGA 122
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
+A V + +PD +S E L EP CV + + G+++L++G G IG
Sbjct: 123 FAPLVTARAQGAFTIPDALSFEIAALTEPL-CVGRRAVKTGEVSPGDRVLVLGPGTIGQS 181
Query: 490 WVTSLHQLGHRDVTVSEMN-KVRLEIVNKL--ETGYRLVTPDV---LEKEKQLYDVIIDC 329
G + ++ MN RLE+ N+L + Y L P ++ + DV+ +
Sbjct: 182 IAVFARAAGAAQIGIAGMNDPARLEVCNRLGFDQTYDLSDPGARTRMQADFDEADVVFEA 241
Query: 328 TGVGKVMEISFNYLRHGGKYVLFG 257
TG + ++ LR G V+ G
Sbjct: 242 TGRDESVQDGLGLLRMEGILVMTG 265
>UniRef50_A0QS68 Cluster: 2-deoxy-scyllo-inosamine dehydrogenase;
n=1; Mycobacterium smegmatis str. MC2 155|Rep:
2-deoxy-scyllo-inosamine dehydrogenase - Mycobacterium
smegmatis (strain ATCC 700084 / mc(2)155)
Length = 341
Score = 77.8 bits (183), Expect = 3e-13
Identities = 72/281 (25%), Positives = 118/281 (41%), Gaps = 13/281 (4%)
Frame = -1
Query: 847 EFSGTITDVGKKSV-FRNGQKVVVDPNRACSLCDFCRKGKYQYCLTA-GINSTVGIWRDG 674
E G + VG+ F G++V V+PN C C +C G+ C G S G
Sbjct: 59 ELVGVVDAVGEGVTRFGIGEQVTVNPNVYCGQCPYCLAGRLGQCAAMLGYGSNF----PG 114
Query: 673 GWAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGN 494
+A+Y V+ +G+ + EP +C HG + + G L++GAG G
Sbjct: 115 FFAEYAIADHTLVFST-EGLPLDTAVFSEPTACAMHGLESLQ-MRPGGSALVLGAGPTGL 172
Query: 493 LWVTSLHQLGHRDVTVSEMNKVRLEIVNKL--ETGYRLVTPD---------VLEKEKQLY 347
L + G VTV+ + +L+ + L + R+ D Y
Sbjct: 173 LLAQLIAAGGASSVTVAGPTQAKLDTASALGIDRTVRISRDDPEGNIAALMAASPHGDGY 232
Query: 346 DVIIDCTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIGVKINPF 167
D +++ TG V +I R GG +++G +PF ++ +E+TI G
Sbjct: 233 DAVVEATGSPAVGDICVPLARRGGTVLIYGVTREDDLVRFHPFDVFRREITIKGSFAEMT 292
Query: 166 SFPNALGWLKAMGNRYVNYEKLGVKTYALSEYESALKDLRA 44
SF A+ L+ G R V + + +AL +Y AL+ LR+
Sbjct: 293 SFGAAIDALR--GGR-VRTDGIITHRFALDDYGRALEALRS 330
>UniRef50_O28179 Cluster: Alcohol dehydrogenase, zinc-dependent;
n=1; Archaeoglobus fulgidus|Rep: Alcohol dehydrogenase,
zinc-dependent - Archaeoglobus fulgidus
Length = 402
Score = 77.8 bits (183), Expect = 3e-13
Identities = 65/255 (25%), Positives = 124/255 (48%), Gaps = 34/255 (13%)
Frame = -1
Query: 847 EFSGTITDVGKKSVFRNGQKVVVDPNRACSL-----CDFCRKGKYQYC-------LTAGI 704
E G + +VGK++ + G++VV++ +C + CD CRKG + C ++ GI
Sbjct: 89 EVVGEVVEVGKEADAQEGERVVINTALSCRVRGFDDCDACRKGHFAACHNVDRGRISPGI 148
Query: 703 NSTVGIWRD--GGWAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGE 530
+ G RD GGWA+Y + Q+ +P+G+ E EP + H R+ P GE
Sbjct: 149 FT--GTCRDTGGGWAEYFVAHESQLVRVPEGIRDENAVFAEPLTIGIHSALRSFP-DDGE 205
Query: 529 KILIVGAGIIGNLWVTSLHQLGHR-DVTVSEMNKVRLEIVNKLETGYRLVTPDVLE---- 365
+ IVG G+IG + +L LG R ++ ++++ + E+ K +VT + +E
Sbjct: 206 VVAIVGCGVIGICTIIALRHLGFRGEIIGIDISERQAELARKFGAD-GVVTENPVERIAE 264
Query: 364 ----------KEKQLY-----DVIIDCTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQAS 230
++K ++ DV +CTG+ + ++ + + G+ V+ G +
Sbjct: 265 MTGGRVYRPPRDKPMFIGGGVDVAFECTGIPQTVDTALRITKPLGRVVIAG---TVAKMG 321
Query: 229 INPFQIYDKELTIIG 185
++ ++ KEL+++G
Sbjct: 322 VDWAPVFAKELSVLG 336
>UniRef50_Q1AZ51 Cluster: Alcohol dehydrogenase GroES-like protein;
n=2; Bacteria|Rep: Alcohol dehydrogenase GroES-like
protein - Rubrobacter xylanophilus (strain DSM 9941 /
NBRC 16129)
Length = 357
Score = 77.4 bits (182), Expect = 4e-13
Identities = 75/298 (25%), Positives = 128/298 (42%), Gaps = 21/298 (7%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
EF GT+ G+ G +V C C +C + +Y C NST G GG
Sbjct: 65 EFMGTVAAAGEDVEGVEEGDRVTGFSIGVCGSCYWCSRQQYILCPELFRNST-GYGLPGG 123
Query: 670 WAQYVKVPQ----DQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGI 503
+A+YV + ++ +P + E EP S V G A+ + G++++++GAG+
Sbjct: 124 FAEYVPIRNAVVGQSIHPVPSELDDETAATTEPVS-VGVGAIEAAGVRPGDRVVVLGAGM 182
Query: 502 IGNLWVTSLHQLGHRDVTVSEMNKVRLEIVNKL--ETGYRLVTPDVLEKEKQLY------ 347
IGN + + G V V +++ VRLE L + + T D L K+L+
Sbjct: 183 IGNACMQAARAAGAGQVAVIDVSPVRLEAARSLGADAVFDARTGDALSWVKELWGVGRYH 242
Query: 346 -------DVIIDCTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTII 188
DV+++ G ++ +F +R GG V G P A I+ +I K+ I+
Sbjct: 243 FNEGGMADVVVEAAGAPVTVQQAFEMVRSGGAIVFVGL--PEEPAPIDVTKIVHKQPRIV 300
Query: 187 GVKINPFSFPNALGWLKAMGNRYVNYEKLGVKTYALSEYESALK-DLRAGLVXKAMFK 17
G F+ ++ M + + ++L + L + A + LR G K M +
Sbjct: 301 GSLGGDFARA-----IELMASGSIRTKELITHRFPLEDAAEAFETQLRTGEAMKVMIQ 353
>UniRef50_A0UVE8 Cluster: Alcohol dehydrogenase GroES-like; n=1;
Clostridium cellulolyticum H10|Rep: Alcohol
dehydrogenase GroES-like - Clostridium cellulolyticum
H10
Length = 348
Score = 77.4 bits (182), Expect = 4e-13
Identities = 57/183 (31%), Positives = 85/183 (46%), Gaps = 2/183 (1%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
EFSG + ++G+ + G +V P C C C+KG Y C S +G G
Sbjct: 59 EFSGEVAEIGEGVTSVAVGDRVAGVPLVPCLKCGDCQKGDYALCKHY---SFIGSRESGS 115
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
+A+YVK+P+ V D VS EQG EP + HG + GE + I+G G +G
Sbjct: 116 FAEYVKMPERNVVKFNDSVSFEQGAFFEPATVALHGL-LCADYRGGEDVAILGGGTVGMF 174
Query: 490 WVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLVTPDVLEKE-KQLYDVIIDCTGVGK 314
G + V V +++ RL + KL VT + L+K+ K+ D + + G G
Sbjct: 175 TAQWARIFGAKRVFVFDIDNDRLALAKKLGVD---VTINTLDKDFKEQVDKLTNKKGFGF 231
Query: 313 VME 305
V E
Sbjct: 232 VYE 234
>UniRef50_Q1IQV5 Cluster: Alcohol dehydrogenase, zinc-binding; n=2;
Acidobacteria|Rep: Alcohol dehydrogenase, zinc-binding -
Acidobacteria bacterium (strain Ellin345)
Length = 345
Score = 77.0 bits (181), Expect = 6e-13
Identities = 55/234 (23%), Positives = 111/234 (47%), Gaps = 15/234 (6%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
E +G + +VG + G +VV + C +C +C K + C ++ +G
Sbjct: 62 ELAGIVEEVGPGVKRLKKGMRVVALNSAPCGVCFYCSKHQENLCEDL-------LFNNGA 114
Query: 670 WAQYVKVP----QDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGI 503
+A+Y+ +P + + ++PDGVS ++ + EP +CV G + VG+ I ++GAG
Sbjct: 115 YAEYILIPKRIVEKNLLVIPDGVSFDEAAVIEPLACVLRGLHETG-MEVGDTITVIGAGP 173
Query: 502 IGNLWVTSLHQLGHRDVTV----------SEMNKVRLEIVNKLETGYRLVTPDVLEKEKQ 353
IG ++V + G + ++V +M ++ + K++ + V L E +
Sbjct: 174 IGLMFVKAASISGCKVISVVKHDEQVEAAKKMGAHKVVQITKVDDPVKAVIE--LTPEHR 231
Query: 352 LYDVIIDCTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTI 191
D++I+ G E + + +R GG FG C + ++N +++ E+T+
Sbjct: 232 GSDIVIEAVGRPDAWEWTIDMVRKGGTVNFFGGCAKGTKVNLNTERLHYSEITL 285
>UniRef50_A1WT70 Cluster: Alcohol dehydrogenase, zinc-binding domain
protein; n=1; Halorhodospira halophila SL1|Rep: Alcohol
dehydrogenase, zinc-binding domain protein -
Halorhodospira halophila (strain DSM 244 / SL1)
(Ectothiorhodospirahalophila (strain DSM 244 / SL1))
Length = 325
Score = 77.0 bits (181), Expect = 6e-13
Identities = 55/181 (30%), Positives = 85/181 (46%), Gaps = 1/181 (0%)
Frame = -1
Query: 799 NGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGGWAQYVKVPQDQVYLLPD 620
+G + V P +C C C G CL G+ +G RDGG AQ+V+VP++ + +P
Sbjct: 67 DGHRYAVWPGVSCGRCPACHSGVENLCL--GVE-VLGFHRDGGMAQWVQVPRESLIPVPS 123
Query: 619 GVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNLWVTSLHQLGHRD-VTVS 443
V L EP +C + ++A + GE++LI GAG +G L ++ G V +
Sbjct: 124 EVPDVVACLAEPLACGINALNQAR-VEAGERVLIHGAGPVGLLLALAVQARGAEPLVCET 182
Query: 442 EMNKVRLEIVNKLETGYRLVTPDVLEKEKQLYDVIIDCTGVGKVMEISFNYLRHGGKYVL 263
+K L + +G L LE +DV I+ T + LR GG+YV+
Sbjct: 183 AADKAALSARFRTLSGVVL----TLEAPGDGWDVAINATSAPPALSAGLQRLRPGGRYVV 238
Query: 262 F 260
F
Sbjct: 239 F 239
>UniRef50_P38105 Cluster: Starvation-sensing protein rspB; n=36;
Proteobacteria|Rep: Starvation-sensing protein rspB -
Escherichia coli (strain K12)
Length = 339
Score = 77.0 bits (181), Expect = 6e-13
Identities = 68/270 (25%), Positives = 119/270 (44%), Gaps = 7/270 (2%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
EF G I VG+ R G++V VDP +C C C GK C T + +G+ DGG
Sbjct: 60 EFFGVIDAVGEGVESARVGERVAVDPVVSCGHCYPCSIGKPNVCTTLAV---LGVHADGG 116
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
+++Y VP + +P+ V+ + + EP++ A+ P + +L+ GAG IG
Sbjct: 117 FSEYAVVPAKNAWKIPEAVADQYAVMIEPFTIAANVTGHGQP-TENDTVLVYGAGPIGLT 175
Query: 490 WVTSLHQLGH-RDVTVSEMNKVRLEIVNKLETGYRL---VTP--DVLEKEKQLYDVIIDC 329
V L + + ++V V++ RLE + + + TP ++ ++ +IID
Sbjct: 176 IVQVLKGVYNVKNVIVADRIDERLEKAKESGADWAINNSQTPLGEIFTEKGIKPTLIIDA 235
Query: 328 TGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIGVKINPFSFPNAL 149
+++ + + VL G + + + I KEL+I ++N FP +
Sbjct: 236 ACHPSILKEAVTLASPAARIVLMGF--SSEPSEVIQQGITGKELSIFSSRLNANKFPIVI 293
Query: 148 GWLKAMGNRYVNYEKLGVKTYALSEYESAL 59
WL + EKL T+ A+
Sbjct: 294 DWL---SKGLIKPEKLITHTFDFQHVADAI 320
>UniRef50_A1DK00 Cluster: Alcohol dehydrogenase; n=7;
Pezizomycotina|Rep: Alcohol dehydrogenase - Neosartorya
fischeri (strain ATCC 1020 / DSM 3700 / NRRL
181)(Aspergillus fischerianus (strain ATCC 1020 / DSM
3700 / NRRL 181))
Length = 385
Score = 68.5 bits (160), Expect(2) = 6e-13
Identities = 50/175 (28%), Positives = 84/175 (48%), Gaps = 7/175 (4%)
Frame = -1
Query: 847 EFSGTITDVG----KKSVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWR 680
E +G + +VG K R G V ++ AC CD CR G+Y C S+ +
Sbjct: 70 EAAGEVVEVGPTVLKTQAIRVGDIVAIESGVACLECDKCRSGRYNICAKMRFRSSGASFP 129
Query: 679 --DGGWAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAG 506
G +YV P + + LPD +S + G L EP S H +RA + G + ++ GAG
Sbjct: 130 HFQGTLQEYVDHPAEWCHKLPDALSYDDGALLEPLSVCIHSVNRAG-VDQGARCVVFGAG 188
Query: 505 IIGNLWVTSLHQLGHR-DVTVSEMNKVRLEIVNKLETGYRLVTPDVLEKEKQLYD 344
+G L ++ ++ H+ V ++++++ R+ LE G+ V V+ K+ D
Sbjct: 189 AVG-LLCAAVAKIEHKCRVVITDVDEGRVAFA--LEHGFADVGFVVVPKKADTID 240
Score = 28.7 bits (61), Expect(2) = 6e-13
Identities = 20/94 (21%), Positives = 41/94 (43%)
Frame = -1
Query: 346 DVIIDCTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIGVKINPF 167
D + +CTGV ++ S +GG VL G + ++ +E+ ++ V
Sbjct: 268 DHVFECTGVESCVQTSIYATENGGNVVLVGMGTAIQTWPV--AELTGREINVVSVWRYVN 325
Query: 166 SFPNALGWLKAMGNRYVNYEKLGVKTYALSEYES 65
+P A+ + A+ + + + + T+ S ES
Sbjct: 326 CYPRAIEIMNAVKSHALKPDVTKLITHRFSGLES 359
>UniRef50_Q8DIZ5 Cluster: Sorbitol dehydrogenase; n=6;
Cyanobacteria|Rep: Sorbitol dehydrogenase -
Synechococcus elongatus (Thermosynechococcus elongatus)
Length = 366
Score = 76.6 bits (180), Expect = 7e-13
Identities = 71/279 (25%), Positives = 125/279 (44%), Gaps = 15/279 (5%)
Frame = -1
Query: 847 EFSGTITDVGKKSV-FRNGQKVVVDPNRACSLCDFCRKGKYQYC-LTAGINSTVG-IWRD 677
E +G I VG ++ GQ+VVV + C C +C Y C + + +T G I
Sbjct: 74 ETAGEIAAVGDAVTGWQVGQRVVVMHHIPCMHCAYCLNENYSMCHVYKTVTTTAGFIPSG 133
Query: 676 GGWAQYVKVPQDQV-----YLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVG 512
GG+A+YVKVP V +PD +S E+ EP +C +A + G+ +LI G
Sbjct: 134 GGFAEYVKVPGHIVEHGGLIPIPDPISDEEASFVEPTNCCLKAVKKAG-IAPGQTVLITG 192
Query: 511 AGIIGNLWVTSLHQLGHRDVTVSEMNKVRLEIVNKL--ETGYRLVTPDVLEKEKQL---- 350
AG IG +++ ++ G R + +++ R+ ++ + PD+ K + L
Sbjct: 193 AGPIGLMFIMLVNLFGARAIA-TDLLPSRIAKAKEVGAAAAFDARDPDLSAKVQALTHGL 251
Query: 349 -YDVIIDCTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIGVKIN 173
DV + K + R GGK + F P + +NP +Y +E+ ++G +
Sbjct: 252 GVDVSLLAVPSEKAFFQALECTRKGGKILFFAEFPDEVEIPLNPNILYRREIDLMGSYSS 311
Query: 172 PFSFPNALGWLKAMGNRYVNYEKLGVKTYALSEYESALK 56
+ + + NR ++ + L Y LS+ A++
Sbjct: 312 SYRLQSLA--CDIIFNRRIDVKTLVSDRYPLSKLAEAVE 348
>UniRef50_Q62AB8 Cluster: Oxidoreductase, zinc-binding dehydrogenase
family; n=28; Bacteria|Rep: Oxidoreductase, zinc-binding
dehydrogenase family - Burkholderia mallei (Pseudomonas
mallei)
Length = 378
Score = 76.6 bits (180), Expect = 7e-13
Identities = 64/262 (24%), Positives = 123/262 (46%), Gaps = 10/262 (3%)
Frame = -1
Query: 796 GQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGGWAQYVKVPQDQ-VYLLPD 620
G +V+ + C C FC G+Y C + G A+Y+ ++ V+ +PD
Sbjct: 113 GDRVISEQIVPCWSCRFCGHGQYWMCQKHDLYGFQNNVH-GAMAEYMIFTKEAIVHRVPD 171
Query: 619 GVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNLWVTSLHQLGH-RDVTVS 443
+ T++ L EP SC H DRA+ + + +++ GAG +G L + +L H + + V
Sbjct: 172 SIPTDEAILIEPLSCSLHAADRAN-VGFDDVVVVAGAGTLG-LGIIGAARLRHPKQLIVL 229
Query: 442 EMNKVRLEIVNKL--ETGYRLVTPDVLEKEKQL-----YDVIIDCTGVGKVMEISFNYLR 284
+M R + ++ + + +V+EK + + D+ I+ TG + + LR
Sbjct: 230 DMKPERAALARRMGADDVWNPAEENVIEKIRAITGGYGCDIYIEATGHHRAVGQGLAMLR 289
Query: 283 HGGKYVLFGCCPPTHQASINPFQIYD-KELTIIGVKINPFSFPNALGWLKAMGNRYVNYE 107
G++V F +AS++ I D KEL ++G + P+ +P A+ ++ +R ++
Sbjct: 290 KLGRFVEFSVF--NDEASVDWSIIGDRKELDVLGSHLGPYMYPRAIEFI---ASRRIDVR 344
Query: 106 KLGVKTYALSEYESALKDLRAG 41
+ T+ LS + A + G
Sbjct: 345 GIVTHTFPLSRFADAFAVMERG 366
>UniRef50_A4YDY9 Cluster: Alcohol dehydrogenase GroES domain
protein; n=1; Metallosphaera sedula DSM 5348|Rep:
Alcohol dehydrogenase GroES domain protein -
Metallosphaera sedula DSM 5348
Length = 287
Score = 76.6 bits (180), Expect = 7e-13
Identities = 72/269 (26%), Positives = 119/269 (44%), Gaps = 3/269 (1%)
Frame = -1
Query: 811 SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGGWAQYVKVPQDQVY 632
+V R+G + N C +CR+G Y +C +GI DG +Y+ +P ++
Sbjct: 43 AVERDGALYTSEINLVDWTCKYCRRGMYTHCEN---RKALGIDVDGAMREYMDLPGYLLH 99
Query: 631 LLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNLWVTSLHQLGHRDV 452
G+ E+ L EP + V + P +++L++G G +G + L G DV
Sbjct: 100 EDRVGLRPEELSLTEPAAAVLRMVELIHP-SPSDRVLVLGDGPVGIISAAVLEHYGF-DV 157
Query: 451 TVSEMNKVRLEIVNKLETGYRLVTPDVLEKEKQLYDVIIDCTGVGKVMEISFNYLRHGGK 272
++ N R+ + L P K YDV+++ TG K + + Y+RH GK
Sbjct: 158 ELNGHNPERMRVAENLG------IPTTRSSTK--YDVVVEATG-SKALGEAMRYVRHMGK 208
Query: 271 YVLFGCCPPTH--QASINPFQIYDKELTIIGVKINPF-SFPNALGWLKAMGNRYVNYEKL 101
L TH + S++ E+ +IG + PF + A+ +K + R +
Sbjct: 209 IAL----KSTHGLEVSLDVTHAVVNEVQLIGSRCGPFYLWDKAMHLIKELDLRRI----- 259
Query: 100 GVKTYALSEYESALKDLRAGLVXKAMFKI 14
V TY SEYE A +D+ V KA+ I
Sbjct: 260 -VTTYPFSEYERAFQDVLNRKVVKAVLMI 287
>UniRef50_Q1J2J1 Cluster: Alcohol dehydrogenase GroES-like; n=1;
Deinococcus geothermalis DSM 11300|Rep: Alcohol
dehydrogenase GroES-like - Deinococcus geothermalis
(strain DSM 11300)
Length = 359
Score = 76.2 bits (179), Expect = 1e-12
Identities = 64/252 (25%), Positives = 106/252 (42%), Gaps = 14/252 (5%)
Frame = -1
Query: 847 EFSGTITDVGKKSVF-RNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
E G + VG+ R G +V ++P C C FC++G+Y C +T + G
Sbjct: 72 EVMGVVDAVGEGVTHVRPGDRVALEPGVPCRRCAFCKRGEYNLCPDMTFMATPPV--HGA 129
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
+YV P D +LLPD +S + G L EP + V R + G+ + + GAG IG
Sbjct: 130 LGEYVLWPDDFAFLLPDRISDDAGALLEPLA-VGIWAARKGDVRPGQSVAVFGAGPIGCT 188
Query: 490 WVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGY-------------RLVTPDVLEKEKQL 350
+ + G + ++ RL++ K+ + R +T L
Sbjct: 189 TLQAAKAAGATTLIAVDLEDFRLDLARKVGATHTINARNEDPVARIREITRGDLPISHAG 248
Query: 349 YDVIIDCTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIGVKINP 170
DV + G +S R GG VL G PP + S++ +E++I GV
Sbjct: 249 VDVAFETAGSLPTTRMSLAAPRPGGTTVLVG-LPPDSEVSLDIVSAASREVSIRGVFRYA 307
Query: 169 FSFPNALGWLKA 134
+P A+ +++
Sbjct: 308 NCYPAAIALVES 319
>UniRef50_A6TKR3 Cluster: Alcohol dehydrogenase, zinc-binding domain
protein; n=1; Alkaliphilus metalliredigens QYMF|Rep:
Alcohol dehydrogenase, zinc-binding domain protein -
Alkaliphilus metalliredigens QYMF
Length = 342
Score = 76.2 bits (179), Expect = 1e-12
Identities = 60/229 (26%), Positives = 109/229 (47%), Gaps = 8/229 (3%)
Frame = -1
Query: 847 EFSGTITDVGKKSV-FRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
EFS I ++ + + + G V +P C C C +GK C N T+G+ RDG
Sbjct: 63 EFSAEIIEIEENDMGLQKGMIVTANPYFNCGKCYSCLRGKVNCCEN---NETMGVQRDGS 119
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
+A+Y+ +P +++ + G+ + L EP+S H +R + + G+K+L++GAG IG +
Sbjct: 120 FAEYIVMPIERI-VDGKGLDAKTLSLIEPFSISYHAVNRVN-IQKGDKVLVIGAGAIG-I 176
Query: 490 WVTSLHQLGHRDVTVSEMNKVRLEIVNKL--ETGYRLVTPDVLEKEKQL-----YDVIID 332
+ +L +V +S++ RLE K+ + + ++ E+ K + DV I+
Sbjct: 177 FAALAAKLRGAEVYISDIFDERLEAALKMGADGTINVKNENLQERVKDITNGNGMDVCIE 236
Query: 331 CTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIG 185
G+ + + GGK L G + + N + KEL + G
Sbjct: 237 AVGMPETFLDCIENVCFGGKIGLIG--NGKRETTFNHSILLKKELDVYG 283
>UniRef50_Q7S9B3 Cluster: Putative uncharacterized protein
NCU07022.1; n=5; Pezizomycotina|Rep: Putative
uncharacterized protein NCU07022.1 - Neurospora crassa
Length = 437
Score = 76.2 bits (179), Expect = 1e-12
Identities = 45/146 (30%), Positives = 71/146 (48%), Gaps = 3/146 (2%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGI--WRD 677
E SG + +G + S F G +V ++ AC C CRKG+Y C S+
Sbjct: 85 ESSGVVVAIGPQVSGFSLGDRVALEVGVACGQCTICRKGRYNLCKKMRFRSSAKSVPHYQ 144
Query: 676 GGWAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIG 497
G + + P ++LPD +S + L EP S H +RASP G L++GAG +G
Sbjct: 145 GTLQERINHPAIWCHILPDHISFDAAALLEPLSVGIHAVNRASP-APGSTALVLGAGTVG 203
Query: 496 NLWVTSLHQLGHRDVTVSEMNKVRLE 419
L Q G VT++++++ R++
Sbjct: 204 LLTAAMARQAGCTQVTITDVDQGRVD 229
>UniRef50_Q1AVM7 Cluster: Alcohol dehydrogenase GroES-like protein;
n=1; Rubrobacter xylanophilus DSM 9941|Rep: Alcohol
dehydrogenase GroES-like protein - Rubrobacter
xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 341
Score = 75.8 bits (178), Expect = 1e-12
Identities = 76/287 (26%), Positives = 126/287 (43%), Gaps = 12/287 (4%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
EF+GT+ +G G +VV + C C+ C G Q C VG+ RDGG
Sbjct: 64 EFAGTVEALGPGVERVAPGDRVVAVAIQGCGRCELCLAGLTQLCPD---RVAVGLSRDGG 120
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
A+Y +P+ + +P+G+ LCEP S D + + K+++ G G IG L
Sbjct: 121 MAEYAVMPEGHLVSVPEGLDLTLAALCEPLSVAVRAVDARAGIAPEGKVVVSGPGPIGIL 180
Query: 490 WVTSLHQLGHRDVTVSEMN---KVRLEIVNKLETGYRLVTPDVLEKEKQLY-------DV 341
+ +L DV ++ + +VRL + G R E+ L DV
Sbjct: 181 -CAMVARLRGADVLLTGIGQDAEVRLPAAER--AGIRAANLSEASLEEHLRDAFGRPPDV 237
Query: 340 IIDCTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTII-GVKINPFS 164
I+ +G + +E + +R GG V+ G + ++ P +EL+++ N
Sbjct: 238 WIESSGSVRALESALESVRAGGTVVVVGIY--AERLNLFPTDAVRRELSLLFSYSCNLAD 295
Query: 163 FPNALGWLKAMGNRYVNYEKLGVKTYALSEYESALKDLRAGLVXKAM 23
+ AL L A G+ ++ L + T+ L E AL+ + AG KA+
Sbjct: 296 YRTALE-LLASGD--LDLGPL-ISTHRLEEAPDALEAVAAGRTVKAV 338
>UniRef50_Q5HLF5 Cluster: Sorbitol dehydrogenase, putative; n=10;
Bacilli|Rep: Sorbitol dehydrogenase, putative -
Staphylococcus epidermidis (strain ATCC 35984 / RP62A)
Length = 350
Score = 75.4 bits (177), Expect = 2e-12
Identities = 64/216 (29%), Positives = 96/216 (44%), Gaps = 7/216 (3%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
EFSG + +VGK S F+ G +VVV+P + R+ L G S +G+ DG
Sbjct: 71 EFSGVVENVGKDVSRFKKGDRVVVNPTVSK------REKPENVDLYDGY-SFIGLGSDGA 123
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
+A++ P+ VY LPD VS +G L EP + VA + LL G+ + + GAG IG L
Sbjct: 124 FAEFTNAPETNVYHLPDNVSAREGALVEP-TAVAVQAVKEGELLFGDTVAVFGAGPIGLL 182
Query: 490 WVTSLHQLGHRDVTVSEMNKVRLEIVNKL------ETGYRLVTPDVLEKEKQLYDVIIDC 329
+ + G + V ++++ RL + +G V E DV +
Sbjct: 183 TIVAAKAAGASKIFVFDLSEERLAKAKSVGATHVYNSGNVDPVQTVYEHTDNGVDVSFEV 242
Query: 328 TGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINP 221
GVG ++ S R G V+ H NP
Sbjct: 243 AGVGITLQQSIEVTRPRGTAVIVSIF--GHPVEFNP 276
>UniRef50_A6LBP5 Cluster: Putative uncharacterized protein; n=1;
Parabacteroides distasonis ATCC 8503|Rep: Putative
uncharacterized protein - Parabacteroides distasonis
(strain ATCC 8503 / DSM 20701 / NCTC11152)
Length = 347
Score = 75.4 bits (177), Expect = 2e-12
Identities = 65/263 (24%), Positives = 115/263 (43%), Gaps = 11/263 (4%)
Frame = -1
Query: 847 EFSGTITDVGKKSVFR-NGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
EFSG ++D+G + G++V V P + C C+ C+ +Y+ C +G +GG
Sbjct: 59 EFSGVVSDIGSSTYLSWLGKRVSVFPLKPCFKCNNCKNKEYELCSNYDY---LGSRCNGG 115
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
+A+YV VP + +PD V E+ + EP + H R S G+ ++++G G IG +
Sbjct: 116 FAEYVAVPVWNLLEIPDCVCYEEAAMLEPAAVALHALKR-SGFKKGDTVVVIGPGTIGMI 174
Query: 490 WVTSLHQLGHRDVTVSEMNKVRLEIVNK--LETGYRLVTPDVLE-----KEKQLYDVIID 332
+ LG V + + +L+ +E T DV E + D++ +
Sbjct: 175 LSQMVKLLGASKVVLVGRTQTKLDFAKTYGVENICNSTTSDVSEWVSRNIDSSGADIVFE 234
Query: 331 CTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINP---FQIYDKELTIIGVKINPFSF 161
TG S ++ G V G P ++ +++ K+L I G + F
Sbjct: 235 GTGASMSFNTSLKIVKSSGTIVALG--NPIDDMTLEKDFYWKLLRKQLQIYGTWNSSFGI 292
Query: 160 PNALGWLKAMGNRYVNYEKLGVK 92
N W + + ++ EKL +K
Sbjct: 293 -NDNDWTQVL--YWLENEKLDLK 312
>UniRef50_A1D0R7 Cluster: Alcohol dehydrogenase; n=2;
Trichocomaceae|Rep: Alcohol dehydrogenase - Neosartorya
fischeri (strain ATCC 1020 / DSM 3700 / NRRL
181)(Aspergillus fischerianus (strain ATCC 1020 / DSM
3700 / NRRL 181))
Length = 364
Score = 75.4 bits (177), Expect = 2e-12
Identities = 65/238 (27%), Positives = 104/238 (43%), Gaps = 20/238 (8%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVV-----DPNRACSLCDFCRKGKYQYCLTA---GINST 695
E SGT+ +VG R GQKVVV DP C C +G++ C A GIN+
Sbjct: 72 EISGTVVEVGADVEGIRIGQKVVVNPLLADPQIQAEACTSCLRGRFNTCKRATYYGINAP 131
Query: 694 VGIWRDGGWAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIV 515
GG++ + V + +PD VS L EP + H +R S G+ ILI+
Sbjct: 132 -----GGGFSGEISVNAANIVPVPDNVSLRAAALAEPLAVACHMIER-SGFAAGDNILIL 185
Query: 514 GAGIIGNLWVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRL-------VTPDVLEKEK 356
GAG IG + L G + + +SE++ +R++ +L + V+ VL
Sbjct: 186 GAGPIGLGLLILLRSKGAKKILISEVSDLRIDQAKRLGADIVINPVQESQVSDPVLRAVH 245
Query: 355 QL----YDVIIDCTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELT 194
+L D+ D +G+ ++ + +R GG ++N + +K LT
Sbjct: 246 ELTDEGVDIAFDASGLQATLDTAIASVRPGGTIFNVAIHEKPLSLNLNALSLQEKHLT 303
>UniRef50_A0LL41 Cluster: Alcohol dehydrogenase GroES domain
protein; n=1; Syntrophobacter fumaroxidans MPOB|Rep:
Alcohol dehydrogenase GroES domain protein -
Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB)
Length = 338
Score = 74.9 bits (176), Expect = 2e-12
Identities = 57/230 (24%), Positives = 101/230 (43%), Gaps = 10/230 (4%)
Frame = -1
Query: 847 EFSGTITDVGKKSV-FRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
E + +VG F+ G++V P C C +CR G Y C + + + GG
Sbjct: 57 EIGAEVVEVGSSVTGFKVGERVFAVPKVPCMECHYCRNGHYPQC------AEIKVRLPGG 110
Query: 670 WAQYVKVPQDQV----YLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGI 503
+A+Y+ VP+ V Y LPD ++ +Q EP +CV R + + G+ ++++G G+
Sbjct: 111 FAEYILVPEILVEKGTYHLPDTITYDQSTFIEPLACVVRA-QRLAGIRAGQTVVVLGCGM 169
Query: 502 IGNLWVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRL-VTPDVLEK----EKQLYDVI 338
G L V L + V +++N+ RL +L + DV E + D +
Sbjct: 170 SGLLHV-KLAKARDCRVVAADVNRKRLAFAEQLGADLIVDAAGDVSESFAAAGDKKADAV 228
Query: 337 IDCTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTII 188
+ CT +E ++ + GG V F P + + +E+ I+
Sbjct: 229 MICTSAVSAVEQAWRCVDKGGAIVFFAVPGPGRDIVVPVNDFWTREIRIL 278
>UniRef50_A6X6E2 Cluster: Alcohol dehydrogenase GroES domain
protein; n=1; Ochrobactrum anthropi ATCC 49188|Rep:
Alcohol dehydrogenase GroES domain protein -
Ochrobactrum anthropi (strain ATCC 49188 / DSM 6882 /
NCTC 12168)
Length = 358
Score = 74.5 bits (175), Expect = 3e-12
Identities = 62/277 (22%), Positives = 123/277 (44%), Gaps = 13/277 (4%)
Frame = -1
Query: 847 EFSGTITDVGKKSV-FRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGI--WRD 677
E SG I +G+ GQ V ++P++ C +C FC++G ++C + +
Sbjct: 69 EASGRIKALGEGVTGLVPGQLVAMNPSQPCGICSFCQQGLTRHCSAMRFKGSAMYLPHQQ 128
Query: 676 GGWAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPL---LVGEKILIVGAG 506
G + + + DQ + +P+G+ EP + H +R + LVG+ +++ GAG
Sbjct: 129 GMFRDRIVIAADQCFPVPNGIDPGAAACSEPLAVCLHAANRGEAIAGSLVGKVVMVTGAG 188
Query: 505 IIGNLWVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRL---VTPDVL---EKEKQLYD 344
IG L V Q G ++ V+++ L + ++ + + P L ++ K D
Sbjct: 189 PIGALCVAVARQRGASEIIVTDIQDATLAVAARMGADHTVNIATDPTGLARWQEGKGKVD 248
Query: 343 VIIDCTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQI-YDKELTIIGVKINPF 167
++ +C+ + + + LR G V G PT + P + KE+ +G +
Sbjct: 249 LVFECSAAAPAIGDAISCLRPLGTLVQVGVGGPT----VLPLNVMVGKEIQFVGSQRFDT 304
Query: 166 SFPNALGWLKAMGNRYVNYEKLGVKTYALSEYESALK 56
F A ++ +G++ ++ + T L+E SA +
Sbjct: 305 EFAEA---VRLIGSKAIDPRPIITATIPLTEALSAFQ 338
>UniRef50_Q2U8M8 Cluster: Threonine dehydrogenase and related
Zn-dependent dehydrogenases; n=2; Aspergillus|Rep:
Threonine dehydrogenase and related Zn-dependent
dehydrogenases - Aspergillus oryzae
Length = 365
Score = 74.5 bits (175), Expect = 3e-12
Identities = 64/226 (28%), Positives = 94/226 (41%), Gaps = 8/226 (3%)
Frame = -1
Query: 847 EFSGTITDVGKKSVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGGW 668
E SG I S GQ V+VDP CS C C C + G G GG+
Sbjct: 73 ELSGRIIQAPSTSSLSPGQAVIVDPRYYCSSCTACTSSVTNCCQSLGFLGLSG--GGGGF 130
Query: 667 AQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPL--LVGEKILIVGAGIIGN 494
++ V VP ++ +PD + L EP + H R S + G IL++G G +G
Sbjct: 131 SEKVAVPPAMLHQIPDNIDMATATLIEPLAVAWHAV-RCSGVKGFKGLPILVIGGGPVGV 189
Query: 493 LWVTSLHQLGHRDVTVSEMNKVRLEIVNKL-ETGYRLVTPDVLEKEKQLYD-----VIID 332
V L G + VSE + R E + L + + + +V + + L + ++ D
Sbjct: 190 ATVFVLRAWGADQIYVSETARRRREFLQDLVQATFDPIEVNVGSECRSLSNGSGIGLVFD 249
Query: 331 CTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELT 194
C G K +E + + LR G YV P S+ KELT
Sbjct: 250 CAGSQKGLEAACDSLRFHGLYV--NLAVPKSAISLPAMYFMRKELT 293
>UniRef50_Q8R7K0 Cluster: L-threonine 3-dehydrogenase; n=3; cellular
organisms|Rep: L-threonine 3-dehydrogenase -
Thermoanaerobacter tengcongensis
Length = 347
Score = 74.5 bits (175), Expect = 3e-12
Identities = 58/232 (25%), Positives = 106/232 (45%), Gaps = 10/232 (4%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
EF G + ++G+ + + G V + + C C CR G C I +G+ DG
Sbjct: 68 EFVGEVVEIGENVTSVKVGDLVSAETHIVCGKCRACRTGNAHICENTLI---LGVDTDGA 124
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
+A+Y+KVP+ V++ + E + EP H S +VG+ + ++G G IG +
Sbjct: 125 FAEYIKVPESNVWINDKNIPLEILSIQEPLGNAVHTV--FSGDVVGKSVAVIGCGPIGMM 182
Query: 490 WVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLVTP------DVLEKEKQLY--DVII 335
+ L + G + E R E+ +KL R++ P +++ E + Y DV++
Sbjct: 183 AIPLLKRTGAAAIFAIEPADYRRELAHKL-GATRVINPLREDVVSIIKSETEGYGADVVL 241
Query: 334 DCTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASIN-PFQIYDKELTIIGV 182
D +G + Y+ GG+ + G P ++ I+ + K +TI G+
Sbjct: 242 DFSGNPTAIRQGLEYIAKGGRMSILGL--PDNEVPIDITNNVVFKGITIQGI 291
>UniRef50_Q8ELG9 Cluster: Sorbitol dehydrogenase; n=2;
Bacillaceae|Rep: Sorbitol dehydrogenase - Oceanobacillus
iheyensis
Length = 342
Score = 74.1 bits (174), Expect = 4e-12
Identities = 58/226 (25%), Positives = 103/226 (45%), Gaps = 9/226 (3%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
E +G + +VG + F+ G +V V+P + G Y T + +G W G
Sbjct: 60 EVAGEVVEVGSSVTKFKVGDRVTVEPQIGTGESEGVMTGNVNYSDTR-LAPGMGDWL-GT 117
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
A+Y P++QV LPD VS +QG L EP + H + + +++ I+GAG IG L
Sbjct: 118 MAEYFASPEEQVIKLPDSVSYDQGVLVEPLAVGVHAAFKGD-VQPTDRVAILGAGPIGLL 176
Query: 490 WVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLVTPD----VLEKEKQL----YDVII 335
+ ++ G +D+ V+++ L++ ++ + D + + ++ L +D +
Sbjct: 177 TLIAVKAKGVKDIVVTDVLDYSLQVAKEMGASEVINIKDNSNWIHDAKQSLDKGSFDKVF 236
Query: 334 DCTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKEL 197
GV ++ S N LR GG+ V I Q +KE+
Sbjct: 237 ITAGVPGIVNDSLNLLRKGGRVVTVAMFHGQQSVDIEQLQQNEKEI 282
>UniRef50_Q72U55 Cluster: Zinc binding dehydrogenase; n=4;
Leptospira|Rep: Zinc binding dehydrogenase - Leptospira
interrogans serogroup Icterohaemorrhagiae
serovarcopenhageni
Length = 348
Score = 74.1 bits (174), Expect = 4e-12
Identities = 60/229 (26%), Positives = 100/229 (43%), Gaps = 8/229 (3%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
E SG I +VG+ FR G +VV+ +C +C +C++GK C G+ G RDG
Sbjct: 67 ESSGIIEEVGENVRRFRKGDRVVIAAGTSCGVCSYCKEGKENLCKDLGV---FGFDRDGS 123
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGG-LCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGN 494
+A++ V + +Y LPD + +QG L + S H + + + I G G +G
Sbjct: 124 FAEFNIVEERYLYSLPDEIPFDQGAILADAVSTPYHAIRYRGNIQESDTVAIFGCGGLGI 183
Query: 493 LWVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLVTPDVLEKEKQL------YDVIID 332
V + V +++ LE K + +V K L D++ D
Sbjct: 184 HAVAIARAMTKGKVIALDVDSGALENATKYGADEVVNLKEVRNSGKVLKEVSKGVDLLAD 243
Query: 331 CTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIG 185
+G +E S + GG+ VL G + I PF + +K +++ G
Sbjct: 244 FSGYMSNVEDSIRAMNPGGRIVLVGIGRQPLKFQI-PFILIEKMISVSG 291
>UniRef50_Q6AAC4 Cluster: Alcohol dehydrogenase; n=1;
Propionibacterium acnes|Rep: Alcohol dehydrogenase -
Propionibacterium acnes
Length = 351
Score = 74.1 bits (174), Expect = 4e-12
Identities = 76/276 (27%), Positives = 119/276 (43%), Gaps = 13/276 (4%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
EF G ++D+G S +R G +V+V C C++CR G C T S G DGG
Sbjct: 64 EFVGLVSDIGNNVSRYRVGDRVIVPFTLGCGHCEYCRSGHSNVCPTV---SMPGFSYDGG 120
Query: 670 WAQYVKVPQDQVYL--LPDGVS-TEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGII 500
+AQYV VP L LPD V T+ G+ HG + G+ +++ GAG +
Sbjct: 121 FAQYVTVPDADANLVKLPDAVDFTDAAGMGCRLMTAYHGIVEVGQIHPGDWLVVYGAGGV 180
Query: 499 GNLWVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLVT--PDVLEKEKQL----YDVI 338
G L T + +V ++ +L + K+ + + D +E ++L D
Sbjct: 181 G-LSATLVATSAGANVIAVDIADDKLALARKVGAIATINSRETDPVEAVRELTDGGADKS 239
Query: 337 IDCTGVGKVMEISFNYLRHGGKYVLFGCCP--PTHQASINPFQIYDKELTIIGVKINP-F 167
+D G+ + + + N LR G ++ G P ++ + KE+ G P
Sbjct: 240 VDALGISETLHNAVNSLRSRGTHIQIGMTAEGPVGDVALTINDLIAKEIDFRGSFGMPAV 299
Query: 166 SFPNALGWLKAMGNRYVNYEKLGVKTYALSEYESAL 59
F L + A G + +L KT ALSE AL
Sbjct: 300 EFRYLLNQV-AAGK--MKPGQLVTKTIALSEVNDAL 332
>UniRef50_Q3WAW5 Cluster: Zinc-containing alcohol dehydrogenase
superfamily; n=8; Frankia sp. EAN1pec|Rep:
Zinc-containing alcohol dehydrogenase superfamily -
Frankia sp. EAN1pec
Length = 315
Score = 74.1 bits (174), Expect = 4e-12
Identities = 55/206 (26%), Positives = 94/206 (45%), Gaps = 2/206 (0%)
Frame = -1
Query: 799 NGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGGWAQYVKVPQDQVYLLPD 620
+G+ V+V+ C C+FC +G+ C + N+ +GI ++GG + +VP +V +P
Sbjct: 61 DGKPVLVEGLFGCGTCEFCWEGRNNLCDQSPRNA-LGIMQNGGMVEQFRVPTRKVLEMPA 119
Query: 619 GVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNLWVTSLHQLGHRDVTVSE 440
G+ L EP + HG R + G + +VG G IG L + G +V +
Sbjct: 120 GLDVSNASLAEPGAVAWHGV-RLGGIAPGRTVTVVGGGSIGQLAAAAAQTQGADEVVLEA 178
Query: 439 MNKVRLEIVNKLETGYRLVTPDVLEKEKQLYDVIIDCTGVGKVMEISFNYLRHGGKYVLF 260
+ EI ++ G P LYDV+I+ G ++ S ++ GG L
Sbjct: 179 RYPHQHEIRERMGVG----EPTA----GTLYDVVIEAAGSPSSLQRSVELVKPGGTVSLL 230
Query: 259 GCCPPTHQASIN-PFQ-IYDKELTII 188
G H I+ P+ + KE+T++
Sbjct: 231 G----VHHGGIDVPYSALLTKEVTLV 252
>UniRef50_Q5K981 Cluster: L-iditol 2-dehydrogenase, putative; n=6;
Basidiomycota|Rep: L-iditol 2-dehydrogenase, putative -
Cryptococcus neoformans (Filobasidiella neoformans)
Length = 400
Score = 73.7 bits (173), Expect = 5e-12
Identities = 50/180 (27%), Positives = 84/180 (46%), Gaps = 3/180 (1%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPNRAC--SLCDFCRKGKYQYCLTAGINSTVGIWRD 677
E +G + +VG ++ G +V ++ C + C C G+Y C ST
Sbjct: 115 ESAGEVVEVGPGVEQWKVGDRVAIECGVPCGQASCGPCVTGRYNACPQVVFFSTPPY--H 172
Query: 676 GGWAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIG 497
G +Y P ++ LPD +S E+G LCEP++ +RA L G+ +LI GAG IG
Sbjct: 173 GTLTRYHAHPASWLHRLPDNLSYEEGALCEPFAVALAALERAGNRL-GDPVLICGAGPIG 231
Query: 496 NLWVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLVTPDVLEKEKQLYDVIIDCTGVG 317
+ + + H G + ++++ RLE+ KL + V + K+ + I + G G
Sbjct: 232 LVTLLASHAAGCTPIVITDLQASRLEVAKKLIPTVKTVQIERSWTSKETSEAIKEAAGTG 291
>UniRef50_Q6MJG4 Cluster: Putative alcohol dehydrogenase I; n=1;
Bdellovibrio bacteriovorus|Rep: Putative alcohol
dehydrogenase I - Bdellovibrio bacteriovorus
Length = 332
Score = 73.3 bits (172), Expect = 7e-12
Identities = 48/200 (24%), Positives = 85/200 (42%), Gaps = 3/200 (1%)
Frame = -1
Query: 847 EFSGTITDVGKK--SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDG 674
E G + + G + F G V C C++CR G C + +G+ +DG
Sbjct: 60 EACGEVVEKGSEVFGTFNPGDLYAVHGPNPCGHCNYCRTGHDNLCNDPS-RTFIGLGQDG 118
Query: 673 GWAQYVKVPQDQVYLLPDGVSTEQGGLC-EPYSCVAHGYDRASPLLVGEKILIVGAGIIG 497
+A+Y+KVP + +P G+S E + + H + +G K+L +G G +G
Sbjct: 119 AYAEYLKVPARNIVKVPKGISPEVAAVATDAVLTPYHAIKTKGGVGLGSKVLAIGLGGLG 178
Query: 496 NLWVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLVTPDVLEKEKQLYDVIIDCTGVG 317
V LG +VT ++ LE L + + +DV++D G+
Sbjct: 179 MNGVQIALALG-AEVTAVDLKDANLETAKSFGVQKVLNSKQISSLTPLSFDVVVDFVGLE 237
Query: 316 KVMEISFNYLRHGGKYVLFG 257
+ + N+++ GG +L G
Sbjct: 238 STFKDAQNFVKPGGTILLIG 257
>UniRef50_Q01PH7 Cluster: Alcohol dehydrogenase GroES domain
protein; n=3; Bacteria|Rep: Alcohol dehydrogenase GroES
domain protein - Solibacter usitatus (strain Ellin6076)
Length = 343
Score = 73.3 bits (172), Expect = 7e-12
Identities = 57/211 (27%), Positives = 94/211 (44%), Gaps = 10/211 (4%)
Frame = -1
Query: 847 EFSGTITDVGKKSV-FRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGI-NSTVGIWR-D 677
E +G + + G R G +V D C C C +G+ C + + G +R
Sbjct: 60 EAAGEVVETGANVTDLRPGDRVTFDSTVYCGRCFHCTRGEVNLCDNREVLGVSPGPYRRH 119
Query: 676 GGWAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIG 497
G +A+YV VP+ +Y LPD +S EQ L E S H + +P+ +G+ ++VG+G+IG
Sbjct: 120 GAFAEYVSVPRRIMYRLPDSLSYEQAALIEAVSVAVHAVN-LTPVRLGDSAVVVGSGMIG 178
Query: 496 NLWVTSLHQLG-HRDVTVS-EMNKVRLEIVNKLETGYRLVTPDVLEKEKQL-----YDVI 338
L + + G R + V + ++RL I + D ++L D+
Sbjct: 179 LLAMQAAKHAGCTRVIAVDPDEGRLRLAIGAGATDAINPKSTDAAAAIRELTEGRGADLA 238
Query: 337 IDCTGVGKVMEISFNYLRHGGKYVLFGCCPP 245
I+C G + + +R GG L G P
Sbjct: 239 IECVGATDPIRTAIAGVRKGGAVTLVGNVAP 269
>UniRef50_A4AMR5 Cluster: Zn-dependent alcohol dehydrogenase; n=2;
Flavobacteriales|Rep: Zn-dependent alcohol dehydrogenase
- Flavobacteriales bacterium HTCC2170
Length = 337
Score = 73.3 bits (172), Expect = 7e-12
Identities = 59/210 (28%), Positives = 101/210 (48%), Gaps = 7/210 (3%)
Frame = -1
Query: 796 GQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGGWAQYVKVPQDQVYLLPDG 617
G KVV+ P +C+ C CR GK C + +GI DGG + + VP ++ L +
Sbjct: 78 GDKVVIMPYVSCNTCIACRNGKNNCCTNMQV---LGIHTDGGMQEKINVP-IELLLKANE 133
Query: 616 VSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNLWVTSLHQLGHRDVTVSEM 437
++ ++ + EP + AH R S L E ++VG G IG L + L QL + +
Sbjct: 134 LTDDEIAIVEPLAIGAHAISR-SGLSKDETAVVVGCGPIG-LGIMKLAQLEGVQIIAIDN 191
Query: 436 NKVRLEIVNK-LETGYRLV-----TPDVLEKEK-QLYDVIIDCTGVGKVMEISFNYLRHG 278
N RL + + + ++ +V++ K L + D +G +E +Y+ HG
Sbjct: 192 NSERLSFAKEIMGIDHTIIANNDTVNEVMKITKGDLATTVFDASGNKLALESGIHYMSHG 251
Query: 277 GKYVLFGCCPPTHQASINPFQIYDKELTII 188
G+Y+L G + ++P +I+ KE TI+
Sbjct: 252 GRYILVG-LSKGNLNFVHP-EIHAKESTIL 279
>UniRef50_A1SFU6 Cluster: Alcohol dehydrogenase, zinc-binding domain
protein; n=1; Nocardioides sp. JS614|Rep: Alcohol
dehydrogenase, zinc-binding domain protein -
Nocardioides sp. (strain BAA-499 / JS614)
Length = 351
Score = 73.3 bits (172), Expect = 7e-12
Identities = 70/275 (25%), Positives = 119/275 (43%), Gaps = 12/275 (4%)
Frame = -1
Query: 847 EFSGTITDVGKKSV---FRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAG---INSTVGI 686
E++G + +G+ + +R G +V + AC C C +G+Y C G +++ G
Sbjct: 67 EWAGDVVALGEGADTFGWRVGDRVAGTSHSACGACQKCVEGQYNLCENYGRPALHAQYGH 126
Query: 685 WRDGGWAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAG 506
G A Y ++ LPD VS + G L +P S H R + G+ + + GAG
Sbjct: 127 NAQGVNATYAVHNVKSIFRLPDEVSFDVGALADPASIALH-VARRGNIKPGDTVAVTGAG 185
Query: 505 IIGNLWV-TSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLVTPDVLEKEKQL-----YD 344
IG L +L R + V +++ ET T D + + + L D
Sbjct: 186 AIGLLAADAALIDGAARVIVVGRGHRLERAAALGFET-VDTRTGDPVAEVRGLTSGLGAD 244
Query: 343 VIIDCTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIGVKINPFS 164
V+++C GV + + LR GG+ + G PT S+ + EL ++G + +
Sbjct: 245 VVLECAGVPETLIWGMAMLRRGGRCAMVGI--PTEDVSLKCQPLVLDELELVGSRASAGE 302
Query: 163 FPNALGWLKAMGNRYVNYEKLGVKTYALSEYESAL 59
L ++ N + E+L + LSEY+ AL
Sbjct: 303 MRRVLPFI---ANGRMRAEELITHHFPLSEYDKAL 334
>UniRef50_Q97VB8 Cluster: Alcohol dehydrogenase; n=1; Sulfolobus
solfataricus|Rep: Alcohol dehydrogenase - Sulfolobus
solfataricus
Length = 317
Score = 73.3 bits (172), Expect = 7e-12
Identities = 42/140 (30%), Positives = 73/140 (52%)
Frame = -1
Query: 808 VFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGGWAQYVKVPQDQVYL 629
+ G+KV + PN C C+ CR+G Y C ++G+ DGG A+Y+ VP+D V+
Sbjct: 62 ITEKGEKVAIFPNYWCGYCNNCRRGFYNSCKN---KISIGVNADGGMAEYINVPKDFVFR 118
Query: 628 LPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNLWVTSLHQLGHRDVT 449
+P + + G L EP + ++ + EK++I+G G G L V+ + ++ +
Sbjct: 119 IPYTLDLKLGALVEPTAVAVAALNKIDKEI--EKVIIIGGGSTGTL-VSIVAEINGLETF 175
Query: 448 VSEMNKVRLEIVNKLETGYR 389
V E + + EI+ E G+R
Sbjct: 176 VIEKDSRKEEILK--EKGFR 193
>UniRef50_UPI000050F926 Cluster: COG1063: Threonine dehydrogenase
and related Zn-dependent dehydrogenases; n=1;
Brevibacterium linens BL2|Rep: COG1063: Threonine
dehydrogenase and related Zn-dependent dehydrogenases -
Brevibacterium linens BL2
Length = 328
Score = 72.9 bits (171), Expect = 9e-12
Identities = 62/219 (28%), Positives = 104/219 (47%), Gaps = 1/219 (0%)
Frame = -1
Query: 838 GTITDVGKKSV-FRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGGWAQ 662
G I +VG + F G +V ++PN C C++CR+G C T+ +++ V + + G A+
Sbjct: 65 GEIAEVGPGACGFAVGDRVALEPNITCGRCEYCRRGMTSAC-TSRLSAGV-LTQPGFLAE 122
Query: 661 YVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNLWVT 482
V P + + L +S E+ EP + VA R + L E +L++GAG G L +
Sbjct: 123 VVDHPSEFCHRLDAHMSLERAVCAEPLA-VAASAIRRTDLQGSETVLVLGAGAQGLLSIL 181
Query: 481 SLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLVTPDVLEKEKQLYDVIIDCTGVGKVMEI 302
+L GH VSE + R ++ +E G ++ TP + +V+ID GV + +
Sbjct: 182 TLVAQGHHPY-VSEPDDERRQLA--VELGAQVFTPG----QSPAPEVVIDAAGVPEALGA 234
Query: 301 SFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIG 185
++L L G H + F I ++L I G
Sbjct: 235 VVDHLAPFAAVTLVG--EDHHHLGASSFSIVQRQLRIKG 271
>UniRef50_Q8YNV3 Cluster: All4458 protein; n=7; Bacteria|Rep:
All4458 protein - Anabaena sp. (strain PCC 7120)
Length = 318
Score = 72.9 bits (171), Expect = 9e-12
Identities = 66/260 (25%), Positives = 121/260 (46%)
Frame = -1
Query: 793 QKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGGWAQYVKVPQDQVYLLPDGV 614
Q+VV + N C C FCR+G+ +C + V R G +A+Y+ +P + ++++P+ V
Sbjct: 72 QRVVGEINAVCGYCRFCRRGQPTHCENRTVLGIVN--RHGAFAEYLCLPVENLHVVPENV 129
Query: 613 STEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNLWVTSLHQLGHRDVTVSEMN 434
T+ EP + A + L +++L+VG G +G L +L G + V
Sbjct: 130 PTDAATFTEPLA-AALEIQQQIILSRDDRVLVVGDGKLGQLVAQTLALTGCELLVVGRHQ 188
Query: 433 KVRLEIVNKLETGYRLVTPDVLEKEKQLYDVIIDCTGVGKVMEISFNYLRHGGKYVLFGC 254
+ ++ N G + D + + + +D++++CTG + I+ LR G VL
Sbjct: 189 E---KLANLKVRGVQTGLVDAV--QDRAFDIVVECTGNPEGFAIARRALRPRGTLVLKST 243
Query: 253 CPPTHQASINPFQIYDKELTIIGVKINPFSFPNALGWLKAMGNRYVNYEKLGVKTYALSE 74
S++ + E+T+IG + FP AL L A G V+ E L Y L++
Sbjct: 244 Y--AGNLSLDASSLVVDEITLIGSRCG--VFPPALE-LLATGK--VDVEPLIHSQYPLTQ 296
Query: 73 YESALKDLRAGLVXKAMFKI 14
A ++ + V K + ++
Sbjct: 297 GLLAFEEAQRRGVLKVLLEM 316
>UniRef50_A4FFG8 Cluster: Probable alcohol dehydrogenase; n=1;
Saccharopolyspora erythraea NRRL 2338|Rep: Probable
alcohol dehydrogenase - Saccharopolyspora erythraea
(strain NRRL 23338)
Length = 328
Score = 72.9 bits (171), Expect = 9e-12
Identities = 56/149 (37%), Positives = 74/149 (49%), Gaps = 1/149 (0%)
Frame = -1
Query: 847 EFSGTITDVGKKSVFRN-GQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
E G I +VG R+ G+ VV++PN C LC +CR+G+ C GI VGI R G
Sbjct: 61 EGCGRIVEVGPAVTDRSVGELVVIEPNYCCLLCQWCRRGRTAQCERRGI---VGINRPGL 117
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
+Q+ VP + +P+ E+ EP + VA G R S + GE L+VGAG G L
Sbjct: 118 LSQFAAVPARFAWPVPEQWPVERLVCFEPLA-VAQGVVRRSGVRAGESCLVVGAGSQGLL 176
Query: 490 WVTSLHQLGHRDVTVSEMNKVRLEIVNKL 404
SL G V VSE RL + L
Sbjct: 177 ICLSLLAAGITPV-VSEPQPGRLALAVSL 204
>UniRef50_Q4LED7 Cluster: Sorbitol dehydrogenase; n=1; uncultured
crenarchaeote 10-H-08|Rep: Sorbitol dehydrogenase -
uncultured crenarchaeote 10-H-08
Length = 339
Score = 72.9 bits (171), Expect = 9e-12
Identities = 62/265 (23%), Positives = 116/265 (43%), Gaps = 12/265 (4%)
Frame = -1
Query: 805 FRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGGWAQYVKVPQ-----D 641
F G +V V + C C +CR+G C + +++ G+A++ +VP+
Sbjct: 70 FEEGDRVFVHHHVTCGKCYYCREGSPTMC-PLFLQTSID---PCGFAEFFRVPRVNVERG 125
Query: 640 QVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNLWVTSLHQLGH 461
V LPD + + EP +CV RA G + +VGAG G +++ G
Sbjct: 126 AVLRLPDELEWSEAVFIEPAACVLRALRRAG-FRAGHTLSLVGAGPTGTIFIVMAKAFGA 184
Query: 460 RDVTVSEMNKVR--LEIVNKLETGYRLVTPDVLEKEKQL-----YDVIIDCTGVGKVMEI 302
V VSE++K R + + N + ++ D +K ++L D+ + T K +
Sbjct: 185 PVVAVSELSKYRRDMALENGADAAVDPLSEDFAKKCRELTDGLGVDIAVLATPAAKPLST 244
Query: 301 SFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIGVKINPFSFPNALGWLKAMGNR 122
+ + LR GG +LFG + ++ +++ +E I+ + N + L + +
Sbjct: 245 ALDSLRRGGTLLLFGAPEKGEKTEVDFSRLFIEEKNIVTSYSTTEAETNTV--LHMLTKK 302
Query: 121 YVNYEKLGVKTYALSEYESALKDLR 47
++L TY+L + E A + R
Sbjct: 303 VFTLKQLITHTYSLEKAEEAFQRAR 327
>UniRef50_Q39TG2 Cluster: Alcohol dehydrogenase superfamily,
zinc-containing; n=1; Geobacter metallireducens
GS-15|Rep: Alcohol dehydrogenase superfamily,
zinc-containing - Geobacter metallireducens (strain
GS-15 / ATCC 53774 / DSM 7210)
Length = 340
Score = 72.5 bits (170), Expect = 1e-11
Identities = 55/206 (26%), Positives = 91/206 (44%), Gaps = 7/206 (3%)
Frame = -1
Query: 847 EFSGTITDVGKKSV--FRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDG 674
EF+G I +VG + + G ++ P C C C G C + +GI G
Sbjct: 61 EFAGEIVEVGPQVAVGWAQGDRLCTLPYIGCGHCLACLTGMPWQCK---LKKVIGIQTAG 117
Query: 673 GWAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGN 494
G+A+Y +V ++ LP VS ++G L EP + H R S + G+ +L+ GAG IG
Sbjct: 118 GFAEYARVHVNEAVRLPVSVSWQEGALVEPLAIGLHAV-RLSRGVAGKSVLVTGAGPIGL 176
Query: 493 LWVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRL-----VTPDVLEKEKQLYDVIIDC 329
G R V VSE + R ++ + + + V E +L ++I +C
Sbjct: 177 AVALWCRFFGARQVVVSEFDPERSKMALAMGATHAVDAKADVGAQYQEITGELPELIFEC 236
Query: 328 TGVGKVMEISFNYLRHGGKYVLFGCC 251
G+ ++ + G + V+ G C
Sbjct: 237 VGIPGLIAQCVDRAAFGAEIVVVGFC 262
>UniRef50_Q59715 Cluster: Benzyl alcohol dehydrogenase II; n=5;
Pseudomonas|Rep: Benzyl alcohol dehydrogenase II -
Pseudomonas putida
Length = 348
Score = 72.5 bits (170), Expect = 1e-11
Identities = 60/230 (26%), Positives = 98/230 (42%), Gaps = 8/230 (3%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
E SG I VG R G +V ++ + C C CR+G C G+ DGG
Sbjct: 65 EVSGVIEQVGSDVKGLRPGMRVSLESHLPCGTCYTCRRGWAHVCPKTRYP---GVDFDGG 121
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
+A +V VP+ + +P G+ Q + EP+ H S + G +L+ G G IG +
Sbjct: 122 FASFVVVPESVCWPVPCGIPPLQAAMMEPFGLAVHASLEGSG-VSGLNVLVSGCGPIGLM 180
Query: 490 WVTSLHQLGHRDVTVSEMNKVRLEIVNKL--ETGYRLVTPDVLEKEKQL-----YDVIID 332
+ + LG V +++ +RL K+ + V + + L DV ID
Sbjct: 181 NIAAAKALGASKVIAPDIHPLRLTAAAKMGADECINATEESVYKTVRSLLGERGVDVAID 240
Query: 331 CTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIGV 182
+G ++ + HGG+ L G P+H +N + K L + G+
Sbjct: 241 YSGQAAALKELIQSITHGGELRLMGV--PSHDILLNLEEWLFKGLIVRGL 288
>UniRef50_Q3W5D6 Cluster: Zinc-containing alcohol dehydrogenase
superfamily; n=1; Frankia sp. EAN1pec|Rep:
Zinc-containing alcohol dehydrogenase superfamily -
Frankia sp. EAN1pec
Length = 350
Score = 72.5 bits (170), Expect = 1e-11
Identities = 79/287 (27%), Positives = 120/287 (41%), Gaps = 12/287 (4%)
Frame = -1
Query: 847 EFSGTITDVGKKSV-FRNGQKVVVDPNRACSLCDFCRKGKYQYC---LTAGINSTVGIWR 680
EF+G + VG ++V V+P +C CD C+ + C +T GI S
Sbjct: 70 EFAGVVAAVGAGVTDVAVSERVSVEPLYSCGDCDRCQASLPELCRQVMTHGICSN----- 124
Query: 679 DGGWAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGII 500
GG AQ+ VP+ V+ LP +S +G L EP + +G R S + G L+ GAG I
Sbjct: 125 GGGLAQFTTVPRAMVHRLPASMSLAEGALVEPMAVAFNGVLR-SGVEAGGSALVFGAGPI 183
Query: 499 GNLWVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRL--VTPDVLEKEKQL-----YDV 341
G V L +G D+ + E R +L L T DV ++ ++ DV
Sbjct: 184 GMGVVFGLRAVGVADILLVEPASARRAAAERLGVADVLDPNTTDVADEVRRRTGGRGVDV 243
Query: 340 IIDCTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIG-VKINPFS 164
++D G ++ LR G+YV G P+ + E+ + G + P
Sbjct: 244 VLDAAGAPGTFGLAPAVLRARGRYV--GIAVAERPVEFAPWVLARGEIELTGSLGYGPGV 301
Query: 163 FPNALGWLKAMGNRYVNYEKLGVKTYALSEYESALKDLRAGLVXKAM 23
F + + G Y V LS+ AL+DLR G K +
Sbjct: 302 FTRVIDLI--AGGAYPTAG--WVDHVGLSDLHDALQDLRDGRRMKVL 344
>UniRef50_Q01VI1 Cluster: Alcohol dehydrogenase GroES domain
protein; n=1; Solibacter usitatus Ellin6076|Rep: Alcohol
dehydrogenase GroES domain protein - Solibacter usitatus
(strain Ellin6076)
Length = 343
Score = 72.5 bits (170), Expect = 1e-11
Identities = 64/248 (25%), Positives = 102/248 (41%), Gaps = 12/248 (4%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
E +GT+ G + G + ++P C C+FCR G++ C S G G
Sbjct: 63 EPAGTVVKTGTGVGGWSRGDRAALEPALYCYHCEFCRSGRHNICANIRFLSNPG--TPGF 120
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
+ ++V +P + +P +S E + EP + H A+ + E + + GAG IG L
Sbjct: 121 FREFVNLPVSNLLAIPPELSLELATIVEPLAVALHSLKFAA-IQPRETVAVFGAGPIGLL 179
Query: 490 WVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLVTPDVLEKEKQL--------YDVII 335
+ L G + V E R E+ ++ L P L+ +Q+ D I
Sbjct: 180 TIACLKDAGAGRIWVVEPVSHRRELALRMGAAAAL-DPTHLDAARQILSDTARRGVDCAI 238
Query: 334 DCTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYD---KELTIIGVKINPFS 164
DC + R+GG+ VL G H A+ PF++ KEL I V+ +
Sbjct: 239 DCAAREDTTNAAIRAARNGGRVVLTG----IHSAAFVPFEVSPMRRKELAIFNVRRSCHE 294
Query: 163 FPNALGWL 140
AL L
Sbjct: 295 SHEALSML 302
>UniRef50_A5V1N3 Cluster: Alcohol dehydrogenase GroES domain
protein; n=2; Roseiflexus|Rep: Alcohol dehydrogenase
GroES domain protein - Roseiflexus sp. RS-1
Length = 345
Score = 72.5 bits (170), Expect = 1e-11
Identities = 57/211 (27%), Positives = 86/211 (40%), Gaps = 5/211 (2%)
Frame = -1
Query: 802 RNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGGWAQYVKVPQDQVYLLP 623
R G +V +P C CD CR GK C + + R G +A YV VP D LP
Sbjct: 85 RAGVRVTFNPLLTCGACDRCRAGKSNLCRNRQL---ISAHRPGAFATYVAVPADLCIPLP 141
Query: 622 DGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNLWVTSLHQLGHRDVTVS 443
D VS G L EP +C E++ I+GAG IG L + + G + +S
Sbjct: 142 DHVSLTLGSLTEPLACSVRAVAHTG---TPERLAILGAGPIGLLCLVAARAAGIEHILMS 198
Query: 442 EMNKVRLEIVNKLETGYRL-VTPDVLEKEKQL----YDVIIDCTGVGKVMEISFNYLRHG 278
+++ RL + + +VL + D +ID G+ + + + G
Sbjct: 199 DVSDRRLAVARAWGATVTINARHNVLNAVQAFAPGGVDAVIDAVGLTVTRDQAVRAVTPG 258
Query: 277 GKYVLFGCCPPTHQASINPFQIYDKELTIIG 185
G+ V G N I +E+T+ G
Sbjct: 259 GRVVFIGLHEEESMLPAN--YIVRQEITVTG 287
>UniRef50_A4XIU4 Cluster: Alcohol dehydrogenase GroES domain protein;
n=1; Caldicellulosiruptor saccharolyticus DSM 8903|Rep:
Alcohol dehydrogenase GroES domain protein -
Caldicellulosiruptor saccharolyticus (strain ATCC 43494 /
DSM 8903)
Length = 436
Score = 72.5 bits (170), Expect = 1e-11
Identities = 83/305 (27%), Positives = 135/305 (44%), Gaps = 44/305 (14%)
Frame = -1
Query: 838 GTITDVGKK-SVFRNGQKVVVDPNRACSL-----CDFCRKGKYQYCL--TAGI---NSTV 692
G I + G+ + F+ G +V+VDP C C C++ ++ CL T G + +
Sbjct: 122 GVIVEKGENVTEFKIGDRVIVDPVLDCDARELPRCPSCQEEEFSTCLNITEGKLKPGTIM 181
Query: 691 GIWRD--GGWAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILI 518
G G W +Y + QV +PD V E+ L +P + H R P + +L+
Sbjct: 182 GACSSTGGSWGEYFVAHKSQVIKVPDSVKDEEAILVDPLASALHPVMRNFP-KDSDMVLV 240
Query: 517 VGAGIIGNLWVTSLHQLGHR-DVTVSEMNKVRLEIVNKLETG-YRLVTP--DVLEK---- 362
GAGIIG L + SL +LG + D+T K + ++ +E G R+V P D LE+
Sbjct: 241 YGAGIIGLLIIWSLRKLGCKADITAIAKYKFQADLA--IEFGANRVVRPSEDYLEEFAKV 298
Query: 361 -----------EKQL---YDVIIDCTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASIN 224
EK L +D + DC G K + + G YVL G +
Sbjct: 299 CGAKVFKPMIGEKVLLGGFDKVFDCVGSKKTIRDGMWLTKQRGSYVLVGLASVVKNLDLT 358
Query: 223 PFQIYDKELTIIGV------KINPF---SFPNALGWLKAMGNRYVNYEKLGVKTYALSEY 71
P I+ KEL + G IN + ++ AL ++ G + Y+KL + +++Y
Sbjct: 359 P--IWFKELNVKGAYCYSTESINEYRVSTYQLALNLIQQFG---IPYDKLITHYFNINDY 413
Query: 70 ESALK 56
+ A++
Sbjct: 414 QKAIE 418
>UniRef50_A0QTC9 Cluster: 2-deoxy-scyllo-inosamine dehydrogenase;
n=1; Mycobacterium smegmatis str. MC2 155|Rep:
2-deoxy-scyllo-inosamine dehydrogenase - Mycobacterium
smegmatis (strain ATCC 700084 / mc(2)155)
Length = 360
Score = 72.5 bits (170), Expect = 1e-11
Identities = 68/282 (24%), Positives = 117/282 (41%), Gaps = 15/282 (5%)
Frame = -1
Query: 847 EFSGTITDVGKKSVFRN--GQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDG 674
E +G + VG + + G +VV+ P R+C C CR G+ C S +G + DG
Sbjct: 72 EAAGIVESVGDPADASSLTGTRVVISPVRSCGDCHACRTGRENVCERV---SVLGCYEDG 128
Query: 673 GWAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGN 494
A V VP ++ +PD V +E L EP S R P + GE L++G G IG
Sbjct: 129 TLATRVVVPVSALHQVPDAVPSELAPLSEPASIALQAVRRGRP-VAGELALVLGCGPIGL 187
Query: 493 LWVTSLHQLGHRDVTVSEMNKVRLEIVNK--------LETGYRLVTPDVL-----EKEKQ 353
+ + +L + G DV + + R + + G R + + + +
Sbjct: 188 ITIMALRRAG-VDVVAVDTVEERARFAERFGAVATIAVAPGQRCPSHEEVAAAAGSGPTR 246
Query: 352 LYDVIIDCTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIGVKIN 173
++I+ TG + + + + H G+ V+ G ++ I KEL ++G + +
Sbjct: 247 AVSLVIEATGSPAALASAIDVVSHAGRVVIVGI--SDQDVTLPHRTIAFKELDVLGSRNS 304
Query: 172 PFSFPNALGWLKAMGNRYVNYEKLGVKTYALSEYESALKDLR 47
P+ LG + + L + E AL+ LR
Sbjct: 305 VGLIPDGLG---LIAQNQAAFSSLITHRFPFEETADALRTLR 343
>UniRef50_A0LRZ3 Cluster: Alcohol dehydrogenase GroES domain
protein; n=1; Acidothermus cellulolyticus 11B|Rep:
Alcohol dehydrogenase GroES domain protein -
Acidothermus cellulolyticus (strain ATCC 43068 / 11B)
Length = 336
Score = 72.5 bits (170), Expect = 1e-11
Identities = 59/221 (26%), Positives = 93/221 (42%)
Frame = -1
Query: 847 EFSGTITDVGKKSVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGGW 668
E++G + + G+ + G +VVV+ C C C G C T +G R G
Sbjct: 64 EWTGVVAEPGRGGLAA-GTRVVVEGIVPCGRCTACAAGATNRCDTY---DELGFTRYGAA 119
Query: 667 AQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNLW 488
A+ V+ P V+ L VS E L EP S V G R SP+ G ++L++G G IG L
Sbjct: 120 AELVRAPAHLVHPLAPQVSEESAVLTEPASVVFTGLSRVSPV-PGWRVLVIGDGTIGLLA 178
Query: 487 VTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLVTPDVLEKEKQLYDVIIDCTGVGKVM 308
H +VT+ + + G T D +D++++ G +
Sbjct: 179 ARLAHLWSPSEVTLLGRRTEQAGLA--ASAGADQFTVDTEAVPAGHFDLVVEAAGSAAAV 236
Query: 307 EISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIG 185
+F +R GG +L G A + + + +LTI G
Sbjct: 237 RTAFAAVRRGGVVLLLGYLGGPPGAELPVDDVVNGDLTIAG 277
>UniRef50_Q5KAN3 Cluster: Xylitol dehydrogenase, putative; n=1;
Filobasidiella neoformans|Rep: Xylitol dehydrogenase,
putative - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 375
Score = 72.5 bits (170), Expect = 1e-11
Identities = 78/303 (25%), Positives = 123/303 (40%), Gaps = 34/303 (11%)
Frame = -1
Query: 847 EFSGTITDVGKK--SVF--RNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWR 680
E G IT VG S F + G +V ++ C C CR+G+Y C S+ +
Sbjct: 55 ESCGVITAVGSNVNSGFNLKVGDRVAMEVGVYCKTCKMCRRGRYNLCANMRFASSAKTYP 114
Query: 679 --DGGWAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAG 506
DG + + P + VY LP + L EP S V H Y RA L G +IL++GAG
Sbjct: 115 HLDGTLREVMTWPAELVYKLPPNLELPLAALAEPLSVVLHAYRRAH-LSPGSRILVIGAG 173
Query: 505 IIGNLWVTSLHQLGHRDVTVSEMNKVRLEIVNK---------LETGYRLVTPDVLE-KEK 356
+G L G V ++ + +L+ + L G R+ + LE K
Sbjct: 174 AVGLLTCALARASGCTTVVAVDIEQGKLDFAAQQSWTTNTFCLPKGPRVSGAEALEVAGK 233
Query: 355 QL------------------YDVIIDCTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQAS 230
Q +D + +CTGV M+++ G K + G
Sbjct: 234 QWDALKASDAVQSVEGLEDGFDAVFECTGVESCMQMAPMAAAIGTKVLFVGMGTKVLALP 293
Query: 229 INPFQIYDKELTIIGVKINPFSFPNALGWLKAMGNRYVNYEKLGVKTYALSEYESALKDL 50
P + E+ +IGV ++P+AL L + + + K+ Y+L + A +DL
Sbjct: 294 CGPSLL--SEVDLIGVFRYCNTYPDALALLAS--GKLGDVSKMASHYYSLDQAAEAFEDL 349
Query: 49 RAG 41
+ G
Sbjct: 350 KRG 352
>UniRef50_Q9S270 Cluster: Putative zinc-binding alcohol
dehydrogenase; n=3; Actinomycetales|Rep: Putative
zinc-binding alcohol dehydrogenase - Streptomyces
coelicolor
Length = 358
Score = 72.1 bits (169), Expect = 2e-11
Identities = 63/225 (28%), Positives = 92/225 (40%), Gaps = 4/225 (1%)
Frame = -1
Query: 796 GQKVVVDPNRACSLCDFCRKGKYQYCL-TAGINSTVGIWR-DGGWAQYVKVPQDQVYLLP 623
G V V P C +C C + C T + S GG+A + VP Q+ LP
Sbjct: 93 GTSVAVHPATPCGVCPECVDRRRNVCRDTRYLGSAARFPHVQGGFAARIVVPAGQLRPLP 152
Query: 622 DGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNLWVTSLHQLGHRDVTVS 443
G+ + L EP S H RA G +L+ GAG IG L V + G VTV+
Sbjct: 153 AGLDPRRAALAEPLSVALHAVRRAGD-PAGRHVLVTGAGPIGCLVVAAAKAAGAAHVTVT 211
Query: 442 EMNKVRLEIVNK--LETGYRLVTPDVLEKEKQLYDVIIDCTGVGKVMEISFNYLRHGGKY 269
++ LE +T R PD ++ D ++ +GV ++ +R GG
Sbjct: 212 DLLPAALEYARAAGADTLVRADDPDDAGWPVEV-DTAVEASGVAAGLDTCLRLVRRGGVV 270
Query: 268 VLFGCCPPTHQASINPFQIYDKELTIIGVKINPFSFPNALGWLKA 134
V G PP Q+ + +E+ + G F +AL L A
Sbjct: 271 VQLGMLPP-GQSPFAGNLLVSREIELRGAFRFDGEFDDALRLLAA 314
>UniRef50_Q025V7 Cluster: Alcohol dehydrogenase GroES domain
protein; n=2; Bacteria|Rep: Alcohol dehydrogenase GroES
domain protein - Solibacter usitatus (strain Ellin6076)
Length = 339
Score = 72.1 bits (169), Expect = 2e-11
Identities = 73/279 (26%), Positives = 114/279 (40%), Gaps = 10/279 (3%)
Frame = -1
Query: 847 EFSGTITDVGKKSV-FRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
E SGT+ VG+ ++ G +V V P C C CR G C +GI G
Sbjct: 61 EMSGTLAAVGEGVAGWQAGDRVTVRPLDPCGTCPACRMGHSHICHNLKF---IGIDTPGA 117
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
VP ++ LPD +S +G + EP + H R S L GE +++G G IG L
Sbjct: 118 LQGMWTVPAHTLHRLPDSLSLREGAMVEPIAVACHDV-RMSELQAGEFAVVIGGGPIGIL 176
Query: 490 WVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLVTPDVLEKEKQL--------YDVII 335
G R V +E+N RL++ L G V P + + DV+
Sbjct: 177 IALVAKARGAR-VLQAEVNPFRLQLARDL--GIDAVNPAETDLPALVNQHTAGAGADVVF 233
Query: 334 DCTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIGVKI-NPFSFP 158
+ +G E+ R G+ V+ + + F+ + +EL + G ++ P F
Sbjct: 234 EVSGSSAGCEMMTRLPRTRGRIVVVAIYAEPQKVDL--FRFFWRELRLAGARVYEPEDFD 291
Query: 157 NALGWLKAMGNRYVNYEKLGVKTYALSEYESALKDLRAG 41
A+ L A G + ++L LS E A+ + G
Sbjct: 292 GAIA-LAASGK--LPLDRLITDVLPLSRLEEAMHRMERG 327
>UniRef50_Q4WT03 Cluster: L-arabinitol 4-dehydrogenase; n=5;
Trichocomaceae|Rep: L-arabinitol 4-dehydrogenase -
Aspergillus fumigatus (Sartorya fumigata)
Length = 359
Score = 72.1 bits (169), Expect = 2e-11
Identities = 55/211 (26%), Positives = 100/211 (47%), Gaps = 14/211 (6%)
Frame = -1
Query: 847 EFSGTITDVGKKSV-FRNGQKVVVDPNRACS--LCDFCRKGKYQYCLTAGINSTVGIWRD 677
E +G + +G+ F+ G +V ++ CS C FCR GKY C ST
Sbjct: 72 ESAGVVLQIGEAVTRFKPGDRVALECGVPCSKPTCSFCRTGKYHACPDVVFFSTPP--HH 129
Query: 676 GGWAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIG 497
G +Y P+ ++ +PD +S E+G L EP S G +R S L + + ++I GAG IG
Sbjct: 130 GTLRRYHAHPEAWLHKIPDNISFEEGSLLEPLSVALAGINR-SGLRLADPLVICGAGPIG 188
Query: 496 NLWVTSLHQLGHRDVTVSEMNKVRL----EIVNKLETGY--RLVTPD-----VLEKEKQL 350
+ + + G + ++++++ RL E+V ++ + + +P ++ + Q
Sbjct: 189 LITLLAASAAGAEPIVITDIDENRLSKAKELVPRVHPVHVQKQESPQHLGARIVRELGQE 248
Query: 349 YDVIIDCTGVGKVMEISFNYLRHGGKYVLFG 257
++++CTGV + R GG + G
Sbjct: 249 AKLVLECTGVESSVHAGIYATRFGGMVFVIG 279
>UniRef50_P22144 Cluster: D-xylulose reductase; n=8;
Saccharomycetales|Rep: D-xylulose reductase - Pichia
stipitis (Yeast)
Length = 363
Score = 72.1 bits (169), Expect = 2e-11
Identities = 71/288 (24%), Positives = 119/288 (41%), Gaps = 19/288 (6%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPNRACSLCDFCRKGKYQYC----LTAGINSTVGIW 683
E +GT+ VGK + + G V ++P D + G Y C A NS G
Sbjct: 67 ESAGTVVQVGKGVTSLKVGDNVAIEPGIPSRFSDEYKSGHYNLCPHMAFAATPNSKEGEP 126
Query: 682 RDGGW-AQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAG 506
G +Y K P+D + LPD VS E G L EP S H + + G+ + + GAG
Sbjct: 127 NPPGTLCKYFKSPEDFLVKLPDHVSLELGALVEPLSVGVHA-SKLGSVAFGDYVAVFGAG 185
Query: 505 IIGNLWVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLVTPDVLEKEK-------QLY 347
+G L G + V V ++ +L++ + E+ +
Sbjct: 186 PVGLLAAAVAKTFGAKGVIVVDIFDNKLKMAKDIGAATHTFNSKTGGSEELIKAFGGNVP 245
Query: 346 DVIIDCTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIGVKINPF 167
+V+++CTG +++ + + GG++V G I F + KELT+ G F
Sbjct: 246 NVVLECTGAEPCIKLGVDAIAPGGRFVQVGNAAGPVSFPITVFAM--KELTLFGSFRYGF 303
Query: 166 S-FPNALG-----WLKAMGNRYVNYEKLGVKTYALSEYESALKDLRAG 41
+ + A+G + N +++E+L Y + A +RAG
Sbjct: 304 NDYKTAVGIFDTNYQNGRENAPIDFEQLITHRYKFKDAIEAYDLVRAG 351
>UniRef50_Q3MCP8 Cluster: Zinc-containing alcohol dehydrogenase
superfamily; n=6; Bacteria|Rep: Zinc-containing alcohol
dehydrogenase superfamily - Anabaena variabilis (strain
ATCC 29413 / PCC 7937)
Length = 368
Score = 71.7 bits (168), Expect = 2e-11
Identities = 83/302 (27%), Positives = 132/302 (43%), Gaps = 23/302 (7%)
Frame = -1
Query: 847 EFSGTITDVGKKSVFRNGQKVVVDPNRACSLCDFCRKGKYQY-C---LTAGINSTVGIWR 680
E G ++DV + +D + C C +C K C G+ +
Sbjct: 69 ETGGAVSDVNSNLIQPGAIATFLDVHETCYNCWYCLVAKASTRCPQRKVYGVTYSAKEGL 128
Query: 679 DGGWAQYVKV-PQDQVYLLPDGVSTEQ---GGLCEPYSCVAHGYDRASPLLVGEKILIVG 512
GGW++ + + P +V LP VS +Q GG P + H DRA + +G+ +++ G
Sbjct: 129 LGGWSELIYLKPGVKVLTLPAEVSPKQFIAGGCALPTAL--HAIDRAQ-IQIGDVVVVQG 185
Query: 511 AGIIGNLWVTSLHQL-GHRDVTVSEMNKVRLEIVNKLETGYRLVTP-----DVLEKEKQL 350
G +G L V L L G V V + + RL + L +E+ +L
Sbjct: 186 CGPVG-LSVAILALLSGAGKVIVIDKFESRLAVAKSFGVDETLAIKADDPRQHIERVLEL 244
Query: 349 Y-----DVIIDCTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINP-FQIYDKELTII 188
DVII+ TG+ ++ N R+GG+YV+ G T + INP +I K + I
Sbjct: 245 TNGHGADVIIEATGIPIAVKEGLNMTRNGGRYVIVGHYTNTGEILINPHLEINLKHIDIR 304
Query: 187 GVKINPFS-FPNALGWLKAMGN--RYVNYEKLGVKTYALSEYESALKDLRAGLVXKAMFK 17
G FS F + LK + + + +E L ++Y L+E AL D+ G V KA+ +
Sbjct: 305 GTWGIDFSHFYRMIELLKRHSDPKKNIAWENLISRSYTLNEINQALTDVERGSVLKAVIQ 364
Query: 16 IN 11
N
Sbjct: 365 PN 366
>UniRef50_Q39JN7 Cluster: Zinc-containing alcohol dehydrogenase
superfamily; n=17; Proteobacteria|Rep: Zinc-containing
alcohol dehydrogenase superfamily - Burkholderia sp.
(strain 383) (Burkholderia cepacia (strain ATCC 17760/
NCIB 9086 / R18194))
Length = 352
Score = 71.7 bits (168), Expect = 2e-11
Identities = 58/230 (25%), Positives = 104/230 (45%), Gaps = 9/230 (3%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGI-NSTVGIWR-D 677
E +GT+ +V + + G +V V+P+R C C +C +G CL S + +
Sbjct: 67 EVAGTVAEVAPDVTSVKVGDRVAVNPSRPCGACRYCLEGLPNQCLDMRFYGSAMRMPHVQ 126
Query: 676 GGWAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIG 497
G + + Q + D V L EP++ H RA P L+G+++L+ G G IG
Sbjct: 127 GAFRNALVCDAVQCVKVADHVPLSLAALAEPFAVGLHAVSRAGP-LIGKRVLVSGCGPIG 185
Query: 496 NLWVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRL-VTPDV--LEK---EKQLYDVII 335
L V + G ++ +++ + LE+ + L + D +E+ +K +DV+I
Sbjct: 186 VLAVAAARVHGAAEIVATDVVEAPLEVASALGADRTINAATDAGWVERYAADKGTFDVMI 245
Query: 334 DCTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIG 185
+C+G + + + +R G V G S+ + KEL+I G
Sbjct: 246 ECSGNARALRDGLDVMRPRGVVVQLGL---GGDVSLPQNVVVAKELSICG 292
>UniRef50_Q0RW76 Cluster: Probable Zn-containing alcohol
dehydrogenase; n=1; Rhodococcus sp. RHA1|Rep: Probable
Zn-containing alcohol dehydrogenase - Rhodococcus sp.
(strain RHA1)
Length = 353
Score = 71.7 bits (168), Expect = 2e-11
Identities = 59/185 (31%), Positives = 86/185 (46%), Gaps = 1/185 (0%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
EFSG +T+V + + + G V V PN A C C+ G C G W GG
Sbjct: 69 EFSGYVTEVAEGVTTVQVGDLVAVRPNFADGTCPSCQAGHPNMCDNFAFIGING-W-GGG 126
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
+++ V VP D Y+LP G + + L EP + H A G L+VGAG IG
Sbjct: 127 FSESVVVPADHAYVLPPGFNAQIAALIEPLTVAWHAVKLAEIPKDG-TALVVGAGPIGLS 185
Query: 490 WVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLVTPDVLEKEKQLYDVIIDCTGVGKV 311
V +L G + VSE ++ R ++ E G LV + +E + + D TG G+
Sbjct: 186 TVLALRAQGISKIIVSEPSEARKKLA--AEVGADLV---IDPRETDVVAAVRDATG-GRG 239
Query: 310 MEISF 296
++SF
Sbjct: 240 ADVSF 244
>UniRef50_Q7QAQ4 Cluster: ENSANGP00000011378; n=3; Culicidae|Rep:
ENSANGP00000011378 - Anopheles gambiae str. PEST
Length = 362
Score = 71.7 bits (168), Expect = 2e-11
Identities = 71/281 (25%), Positives = 111/281 (39%), Gaps = 11/281 (3%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
E SG + VG + + G +V ++P C C C+ G+Y C T G G
Sbjct: 70 ESSGVVVAVGADVTSLQVGDRVAIEPAIGCRTCRHCKAGRYNICPQGVYCVTTG---HGN 126
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
Y D + LP V+ E+G L EP + H R + +G +L++GAG IG +
Sbjct: 127 LCNYYTHAADCCFKLPANVTMEEGALLEPLAVGVHCCRRGG-VGIGSTVLVLGAGPIGLV 185
Query: 490 WVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLV-----TPDVLEKEKQLY-----DV 341
+ +G V V ++ + +LE+ L L T D + K D+
Sbjct: 186 TLLVAKAMGAAKVCVIDLVERKLELAKTLGADATLAVSGHDTQDEIVKRIHALLGTAPDI 245
Query: 340 IIDCTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIGVKINPFSF 161
I+CTG +++ GG L G + I + +E+ I +
Sbjct: 246 SIECTGAEACVQLGIEATVPGGVVTLVGIGAIQQRVPITTALV--REIDIRTAFRYANCY 303
Query: 160 PNALGWLKAMGNRYVNYEKLGVKTYALSEYESALKDLRAGL 38
P AL + N ++ KL Y L E + A R GL
Sbjct: 304 PAALA---MVANGTIDALKLITHHYELQESDQAFNTARYGL 341
>UniRef50_Q0U204 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 377
Score = 71.7 bits (168), Expect = 2e-11
Identities = 58/225 (25%), Positives = 96/225 (42%), Gaps = 28/225 (12%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPNRACSLCDFCRKGKYQYC------LTAGINSTVG 689
E SGTIT VG + F+ G +V ++P C C C+ G Y C G ST G
Sbjct: 76 EASGTITSVGPSVTSFKIGDRVAIEPGTPCRRCAACKSGTYNLCRHMLFAAAPGPPSTPG 135
Query: 688 IWRDGGWAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGA 509
G +++ ++ +D Y++PD +S ++ L EP + H + + GE ++++G
Sbjct: 136 --TPGTLSKFYEMAEDLCYVIPDAISLQEAVLVEPLAVAVHAV-KLGDVRPGETVVVMGC 192
Query: 508 GIIGNLWVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYR-------LVTPDVLEKEKQL 350
G IG L G V + ++ + +++ G + DV EK +
Sbjct: 193 GTIGLLVAAVARLFGALRVVMVDVREDKVKFAKGWMQGAEGFIADVGMSGEDVAEKMLEE 252
Query: 349 Y--------------DVIIDCTGVGKVMEISFNYLRHGGKYVLFG 257
+ D +I+ +G +E LR GGKYV G
Sbjct: 253 FGLKEEGVDTSGGKIDTVIEASGAASCVEAGICMLRPGGKYVQTG 297
>UniRef50_P39713 Cluster: Zinc-type alcohol dehydrogenase-like
protein YAL061W; n=8; Saccharomycetales|Rep: Zinc-type
alcohol dehydrogenase-like protein YAL061W -
Saccharomyces cerevisiae (Baker's yeast)
Length = 417
Score = 71.7 bits (168), Expect = 2e-11
Identities = 54/172 (31%), Positives = 80/172 (46%), Gaps = 15/172 (8%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPNRAC--------------SLCDFCRKGKYQYCLT 713
E +GT+ +VG + G KVVV+P C C C+KG Y C
Sbjct: 74 EMAGTVLEVGPGVKNLKVGDKVVVEPTGTCRDRYRWPLSPNVDKEWCAACKKGYYNICSY 133
Query: 712 AGINSTVGIWRDGGWAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVG 533
G+ G+ + GG+A+ V + + Y +PD V + L +P + H R G
Sbjct: 134 LGLCGA-GV-QSGGFAERVVMNESHCYKVPDFVPLDVAALIQPLAVCWHAI-RVCEFKAG 190
Query: 532 EKILIVGAGIIGNLWVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLVTP 377
LI+GAG IG + +L+ G +D+ VSE KVR E+ K+ G R+ P
Sbjct: 191 STALIIGAGPIGLGTILALNAAGCKDIVVSEPAKVRRELAEKM--GARVYDP 240
>UniRef50_Q1PZD2 Cluster: Strong similarity to L-threonine
dehydrogenase; n=1; Candidatus Kuenenia
stuttgartiensis|Rep: Strong similarity to L-threonine
dehydrogenase - Candidatus Kuenenia stuttgartiensis
Length = 344
Score = 71.3 bits (167), Expect = 3e-11
Identities = 66/287 (22%), Positives = 128/287 (44%), Gaps = 9/287 (3%)
Frame = -1
Query: 847 EFSGTITDVGKKSVF-RNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
EF+G + +VGK+ F + G++V + + +C C C+ G + C + + +GI DG
Sbjct: 64 EFAGYVQEVGKEVTFVKAGERVSAETHISCGYCYQCKNGYREVCRKSKL---LGIDYDGT 120
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
+A+Y+ +P+ ++ + E + EP+ S + + +LI+GAG IG
Sbjct: 121 FAEYLSLPEHVLWKDDPRIPDEWATIQEPFGNAVDTV--MSEDISSKTVLILGAGPIGLF 178
Query: 490 WVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLVTP---DVLE-----KEKQLYDVII 335
V G + VS+ N RL+I K+ + P D+L E DV++
Sbjct: 179 AVGIARACGASLIIVSDPNDYRLDIGKKMGADI-VANPKNTDILNCVLEATEGNGVDVVL 237
Query: 334 DCTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIGVKINPFSFPN 155
+ +G ++ L GG+ + G +N I+ K++ I G+ F
Sbjct: 238 EFSGNKLALDQGLKSLTPGGRISILGIYETPVDIDLNREVIF-KKIRIYGITGRKI-FST 295
Query: 154 ALGWLKAMGNRYVNYEKLGVKTYALSEYESALKDLRAGLVXKAMFKI 14
+ + + V+ + T+ L +YE ++ +R G+ K + ++
Sbjct: 296 WYKTSRFLSSGLVDPGPVITHTFLLEDYEKGMQLMRDGMCGKVVLQV 342
>UniRef50_A1UQB9 Cluster: Alcohol dehydrogenase GroES domain
protein; n=9; Actinomycetales|Rep: Alcohol dehydrogenase
GroES domain protein - Mycobacterium sp. (strain KMS)
Length = 343
Score = 71.3 bits (167), Expect = 3e-11
Identities = 55/204 (26%), Positives = 89/204 (43%), Gaps = 9/204 (4%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
E+SGT+ VG F G +V C C FC++G C G +G +G
Sbjct: 60 EYSGTVVGVGSGVREFTEGDRVCGVGVFGCGECGFCKQGAEALCGAVGF---IGFAVNGA 116
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
A+Y +P ++ +PD +S + + EP + H R S L G + I GAG IG
Sbjct: 117 LARYASLPTKALFRIPDEISLAEAAVVEPIASAYHAV-RRSGLAAGGTVFIAGAGPIGLA 175
Query: 490 WVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLVTP---DVLEKEKQL-----YDVII 335
V G V V+E++ R +++ R++ P D +E + L D+
Sbjct: 176 LVQFSLAKGATQVIVNEVSATRRVAAHRV-GATRVIDPLAEDAVEVVRTLTNGNGVDISF 234
Query: 334 DCTGVGKVMEISFNYLRHGGKYVL 263
D GV ++ + LR G+ ++
Sbjct: 235 DAAGVQPALDAALGVLRPRGRLMV 258
>UniRef50_A6VLA0 Cluster: Alcohol dehydrogenase GroES domain
protein; n=1; Actinobacillus succinogenes 130Z|Rep:
Alcohol dehydrogenase GroES domain protein -
Actinobacillus succinogenes 130Z
Length = 339
Score = 70.9 bits (166), Expect = 4e-11
Identities = 63/271 (23%), Positives = 118/271 (43%), Gaps = 9/271 (3%)
Frame = -1
Query: 847 EFSGTITDVGKKSVF-RNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
EF GT+ + GK + G VV D +C C CR G + C + G+ GG
Sbjct: 61 EFVGTVVETGKAVTHVKVGDYVVSDIVNSCGHCYACRTGHHNVCKNLQVT---GVHSQGG 117
Query: 670 WAQYVKVPQDQVYLL-PDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGN 494
+A+Y K D VYL+ + + + L EPY+ RAS + G+K+++ G+G G
Sbjct: 118 FAEYAKTRADNVYLVDTNKIPHKTACLIEPYAVGVEINTRAS-IAAGDKVVVFGSGPAG- 175
Query: 493 LWVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLVTPDVLEKE--KQLYD-----VII 335
L V + + +V ++++ + RL++ ++ + D+ ++ + D V++
Sbjct: 176 LAVMQVARARGAEVLITDIFEERLQLAREMGATKAINVKDIDMRQAVNEFTDDEGAHVVV 235
Query: 334 DCTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIGVKINPFSFPN 155
D + + + + + G+ V+ G + I K + + G ++N FP
Sbjct: 236 DAVCSPQSILDALDIVAPSGRLVVLG--TGAAPSEIPQVAFTKKGINVFGTRLNNKRFPE 293
Query: 154 ALGWLKAMGNRYVNYEKLGVKTYALSEYESA 62
++ V EK+ TY + E A
Sbjct: 294 V---IRLFEEHKVTPEKMITHTYKFEDIEKA 321
>UniRef50_A0LGB6 Cluster: Alcohol dehydrogenase GroES domain
protein; n=1; Syntrophobacter fumaroxidans MPOB|Rep:
Alcohol dehydrogenase GroES domain protein -
Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB)
Length = 321
Score = 70.9 bits (166), Expect = 4e-11
Identities = 52/206 (25%), Positives = 93/206 (45%), Gaps = 4/206 (1%)
Frame = -1
Query: 790 KVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGGWAQYVKVPQDQVYLLPDGVS 611
+ VV P AC C++CRKG C I +G R GG+A+Y+ P D + +P +
Sbjct: 71 RFVVWPGTACGTCEYCRKGFENLCSAMEI---LGFHRHGGFAEYLAAPADSLVPVPPELP 127
Query: 610 TEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNLWVTSLHQLGHRDVTVSEMNK 431
L EP +C + DR GE++LI GAG +G L + G + +++
Sbjct: 128 GAIACLAEPLACTLNALDRVG-AAPGERLLIYGAGPVGLLMALAARSRG----ALPFLHE 182
Query: 430 VRLEIVNKLETGYRLVTPDVLEKEKQ-LYDVIIDCTGVGKVMEISFNYLRHGGKYVLFGC 254
+ E + + + ++ +++ YDV ++ + + L GG++ +F
Sbjct: 183 INAEKLARSHDFRGQIGAELHREDRPGDYDVAVNAAPAWETLGAGLRNLAAGGRFCVFSG 242
Query: 253 CP---PTHQASINPFQIYDKELTIIG 185
P P IN +I+ ++L + G
Sbjct: 243 FPAGDPVPAGLIN--EIHYRQLVVSG 266
>UniRef50_A3H9A2 Cluster: Alcohol dehydrogenase GroES-like; n=1;
Caldivirga maquilingensis IC-167|Rep: Alcohol
dehydrogenase GroES-like - Caldivirga maquilingensis
IC-167
Length = 360
Score = 70.9 bits (166), Expect = 4e-11
Identities = 62/238 (26%), Positives = 111/238 (46%), Gaps = 11/238 (4%)
Frame = -1
Query: 790 KVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGGWAQYVKVPQDQVYLLPDGVS 611
+VVV PN C C C+ G + C ++G+ G ++Y+ V ++ +PD +S
Sbjct: 80 RVVVFPNYWCDSCIDCKVGHFNTCKN---KVSIGVNAPGALSEYMDVESKYLFKVPDSLS 136
Query: 610 TEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL-WVTSLHQLGHR-DVTVSEM 437
+ L EP + V H + P G+ ILI+G G +G+L + LH+L + ++ + E+
Sbjct: 137 NYEAVLTEPLAVVIHAMKKIDP-KPGDNILIIGGGALGHLTTMLLLHELRDKVNIFIKEI 195
Query: 436 N--KVRL------EIVNKLETGYRLVTPDVLEKEKQLYDVIIDCTGVGKVMEISFNYLRH 281
N KV + ++V+ L + Y ++ D + + + + +M IS N L
Sbjct: 196 NIKKVHILREVFGDLVHILSSIYDYPLEFPYLNGLKIVDTVGNNSSISDIMSIS-NILPS 254
Query: 280 GGKYVLFGCCPPTHQASINPFQIYDKELTIIG-VKINPFSFPNALGWLKAMGNRYVNY 110
G + V+ G +I+ + + +E+ I G + NP F NA+ L M Y
Sbjct: 255 GIRSVILGL--GQKNVNIDLYAVVRREIHIEGSIIYNPSDFINAIEILYNMHKEKYEY 310
>UniRef50_Q89GJ2 Cluster: Bll6353 protein; n=2; Proteobacteria|Rep:
Bll6353 protein - Bradyrhizobium japonicum
Length = 334
Score = 70.5 bits (165), Expect = 5e-11
Identities = 53/201 (26%), Positives = 88/201 (43%), Gaps = 4/201 (1%)
Frame = -1
Query: 847 EFSGTITDVGKKSVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGGW 668
E G + G K +G++ V C C C++G Q CL ++S +G R GG+
Sbjct: 65 EIFGVVEQPGHKL---HGRRCAVYIPLHCGHCAACKRGDTQMCLE--VSSLIGWNRPGGY 119
Query: 667 AQYVKVPQDQVYLLPDGVSTEQGGLC-EPYSCVAHGY---DRASPLLVGEKILIVGAGII 500
A+YV VP++ + +PD + L + H R P +L++GAG +
Sbjct: 120 AEYVPVPENCLLQVPDDIEDSLAPLLLDTIGTSGHAVRFVSRVVPANEAGSVLVMGAGPV 179
Query: 499 GNLWVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLVTPDVLEKEKQLYDVIIDCTGV 320
G V +L LG+ D+ V++ N RL+I T + Q + +I++C+G
Sbjct: 180 GLGVVLALRALGYDDIYVADPNAARLKIAQSFG-----ATAHPVGDSSQRFALIMECSGA 234
Query: 319 GKVMEISFNYLRHGGKYVLFG 257
+ + G VL G
Sbjct: 235 HAARNLGIELVLPRGALVLVG 255
>UniRef50_Q0RXH7 Cluster: Alcohol dehydrogenase; n=1; Rhodococcus
sp. RHA1|Rep: Alcohol dehydrogenase - Rhodococcus sp.
(strain RHA1)
Length = 342
Score = 70.5 bits (165), Expect = 5e-11
Identities = 71/283 (25%), Positives = 118/283 (41%), Gaps = 12/283 (4%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTA---GINSTVGIWR 680
E +G + VG + SV G V++ P C LCD CR G+ YC + G+++T W
Sbjct: 65 ETTGWVEAVGSEVSVVAPGDPVLLHPLITCGLCDGCRAGRDMYCSNSRFPGVDATT--W- 121
Query: 679 DGGWAQYVKVPQDQVYLLP-DGVSTEQGGLCEPYSCVAHGYDRASPLL-VGEKILIVGAG 506
GG+A+Y+ + V LP D E G + H R P L + ++G G
Sbjct: 122 -GGFAEYMLTGERAVVPLPGDADLVELAGFSDAGLTAYHAVKRLVPYLNPNGTVAVIGVG 180
Query: 505 IIGNLWVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLVTP------DVLEKEKQLYD 344
+G+ V L ++ V +++ R ++ +L P VLE D
Sbjct: 181 GVGHFAVQLLREMTSCTVIALDVDSARAQLGEQLGAHASFHGPIETLLESVLELTNGGVD 240
Query: 343 VIIDCTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIGVKINPFS 164
++DC G +++R GG L G +++ KE+TI+ + ++
Sbjct: 241 AVMDCASGGSQSVTPLDFVRKGGTVSLVG---GGASLNVDTLSAVVKEITIVTNLVGTYT 297
Query: 163 FPNALGWLKAMGNRYVNYEKLGVKTYALSEYESALKDLRAGLV 35
L ++ G R ++ T+ LS+ AL L G V
Sbjct: 298 ELQELIGMQRSGLRSLH------TTFPLSDTTEALHALTTGSV 334
>UniRef50_A0QWX1 Cluster: Oxidoreductase, zinc-binding dehydrogenase
family protein; n=3; Bacteria|Rep: Oxidoreductase,
zinc-binding dehydrogenase family protein -
Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
Length = 363
Score = 70.5 bits (165), Expect = 5e-11
Identities = 51/199 (25%), Positives = 85/199 (42%), Gaps = 2/199 (1%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
EFSG + ++G F G+ V V P C CDFC KG++ C G DG
Sbjct: 79 EFSGWVVELGDGVEGFDIGELVSVPPLIPCRRCDFCAKGEFGLCENYDY---FGSRSDGA 135
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
+AQYV P + LP G+ + +P + HG + L G ++L++GAG IG
Sbjct: 136 YAQYVVSPVGNLLKLPAGIDPRAAAMLDPAAIALHGLWKTG-LRAGHRVLVIGAGPIGLF 194
Query: 490 WVTSLHQLGHRDVTVSEMNKVRLEIVNKL-ETGYRLVTPDVLEKEKQLYDVIIDCTGVGK 314
+ G V ++++ + + + T D + +D++++ GV
Sbjct: 195 AIQWAKLHGADQVVAVDLSEEKAAMARQAGATDAVQDAEDARAIGGRGFDIVLESAGVPA 254
Query: 313 VMEISFNYLRHGGKYVLFG 257
+++ N G V G
Sbjct: 255 TADMAANLTGPHGHAVFVG 273
>UniRef50_Q0UEG3 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 320
Score = 70.5 bits (165), Expect = 5e-11
Identities = 42/144 (29%), Positives = 70/144 (48%), Gaps = 2/144 (1%)
Frame = -1
Query: 847 EFSGTITDVGKKSV-FRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
E +G + + G+ + + G +V V+P C C C G+Y C + G++ D G
Sbjct: 52 EAAGVVLECGEGVISLKPGDRVAVEPGVPCETCFLCMDGRYNLCEDVKFS---GVYPDAG 108
Query: 670 WAQYVKV-PQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGN 494
Q K P ++LP VS +G L EP S V HG +++ L +G +I GAG IG
Sbjct: 109 TIQRYKTHPARWCHILPSNVSYSEGALLEPLSVVMHGI-KSAGLSLGRGAVICGAGPIGL 167
Query: 493 LWVTSLHQLGHRDVTVSEMNKVRL 422
+ + + G + ++++ RL
Sbjct: 168 IALAAARASGAHPLVITDLEPNRL 191
>UniRef50_Q4PHJ5 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 382
Score = 70.1 bits (164), Expect = 6e-11
Identities = 42/136 (30%), Positives = 67/136 (49%), Gaps = 2/136 (1%)
Frame = -1
Query: 796 GQKVVVDPNRAC--SLCDFCRKGKYQYCLTAGINSTVGIWRDGGWAQYVKVPQDQVYLLP 623
G +V ++P C + CDFCR GKY C T S +DG +Y + P ++ +P
Sbjct: 99 GDRVAIEPGVPCFKATCDFCRTGKYNLCPTVDFYSVPP--KDGTLKRYHEHPAGWLHKVP 156
Query: 622 DGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNLWVTSLHQLGHRDVTVS 443
D +S E+ L EP S +A + +G +LI GAG IG + + G + ++
Sbjct: 157 DNMSYEEIALLEPLSVTLQATLQAE-ISLGTPVLITGAGPIGIVQLLCASAAGATPIVIT 215
Query: 442 EMNKVRLEIVNKLETG 395
++ K RL+ K+ G
Sbjct: 216 DVVKDRLDFAQKIVPG 231
>UniRef50_A3DME0 Cluster: Alcohol dehydrogenase GroES domain
protein; n=1; Staphylothermus marinus F1|Rep: Alcohol
dehydrogenase GroES domain protein - Staphylothermus
marinus (strain ATCC 43588 / DSM 3639 / F1)
Length = 333
Score = 70.1 bits (164), Expect = 6e-11
Identities = 65/238 (27%), Positives = 107/238 (44%), Gaps = 11/238 (4%)
Frame = -1
Query: 847 EFSGTITDVGKKSVFRN-GQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
E +G I VG+ + G KV + N C C +CR G Y +C T+GI RDGG
Sbjct: 60 EIAGIIDMVGENAPDSLIGHKVTTEINVYCGKCWYCRHGMYTHC---PYRETIGITRDGG 116
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYD--RASPLLVGEKILIVGAGIIG 497
A+YV +D ++++ D + + EP + V + R PL I ++G G IG
Sbjct: 117 MAEYVLTRKDLIHVV-DDLDFDIIAFIEPLAAVVEMIEMQRVEPL---SNIAVLGIGPIG 172
Query: 496 NLWVTSLHQLGHRD--VTVSEMNKVRLEIVNKLETGYRLVTPDVLE------KEKQLYDV 341
L + L +L H D V ++ + +++ + L + LE E Q +D
Sbjct: 173 LLSIQVL-KLFHPDKIVAIARRDSPKIKYAYMVGADEVLTYEEALEYMKQHTPEGQGFDY 231
Query: 340 IIDCTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIGVKINPF 167
+++ TG K ++++ R G V+ S N + KE+ I+G + PF
Sbjct: 232 VVEATGSYKGLDMALKLTRPRG--VIAAKSTHGSNVSFNYTLMVVKEVRIVGSRCGPF 287
>UniRef50_Q62K93 Cluster: Oxidoreductase, zinc-binding dehydrogenase
family; n=41; Bacteria|Rep: Oxidoreductase, zinc-binding
dehydrogenase family - Burkholderia mallei (Pseudomonas
mallei)
Length = 353
Score = 69.7 bits (163), Expect = 8e-11
Identities = 65/257 (25%), Positives = 117/257 (45%), Gaps = 10/257 (3%)
Frame = -1
Query: 796 GQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGGWAQYVKVPQDQ-VYLLPD 620
G +V+ + C C +C+ G+Y C I DGG A+Y+++P V+ +P
Sbjct: 88 GDRVIAEQIVPCGTCRYCKSGQYWMCEVHHIFGFQREVADGGMAEYMRIPSGAIVHPIPL 147
Query: 619 GVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNLWVTSLHQL-GHRDVTVS 443
G+S E + EP +C H +R + + + ++I GAG +G L +T + +L R + V
Sbjct: 148 GISLEDAAIIEPLACAIHTVNRGD-IQLDDVVVIAGAGPLG-LMMTQVAKLKTPRRLVVV 205
Query: 442 EMNKVRLEIVNKLETGY-----RLVTPDVLEKEKQLY--DVIIDCTGVGKVMEISFNYLR 284
+ + R + R P ++ Y DV I+ TGV + +R
Sbjct: 206 DPVEARRALARAYGADVTIDPAREDAPAIVRALTGGYGCDVYIETTGVPAGVTQGMALIR 265
Query: 283 HGGKYVLFGCCPPTHQASINPFQIYD-KELTIIGVKINPFSFPNALGWLKAMGNRYVNYE 107
G++V F +++ I D KEL + G + P+ +P A+ L A G V +
Sbjct: 266 KLGRFVEFSVF--GKDTALDWSIIGDRKELDVRGAHLGPYCYPVAID-LLARG--LVTSK 320
Query: 106 KLGVKTYALSEYESALK 56
+ ++L E++ A++
Sbjct: 321 GIVTHGFSLDEWDEAIR 337
>UniRef50_Q7CVQ9 Cluster: AGR_L_281p; n=7; Alphaproteobacteria|Rep:
AGR_L_281p - Agrobacterium tumefaciens (strain C58 /
ATCC 33970)
Length = 397
Score = 69.7 bits (163), Expect = 8e-11
Identities = 63/233 (27%), Positives = 102/233 (43%), Gaps = 12/233 (5%)
Frame = -1
Query: 847 EFSGTITDVGKKSVFRN-GQKVVVDPNRACSLCD-FCRKGKYQYCLTAGINSTVGI-WRD 677
EF G + +G N G +V + P D F +G + + VG+ W
Sbjct: 111 EFGGVVEAIGDGVTSVNVGDRVSIQPLIMPRSGDYFADRGLFHLSTQLAL---VGLSWDG 167
Query: 676 GGWAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIG 497
GG A+ V + V +PD ++ E+ L EP + + DR + G +L+ GAG IG
Sbjct: 168 GGMAEAALVNEYNVQKIPDEMTDEEAALVEPSAVAVYACDRGG-VTAGNSVLVTGAGPIG 226
Query: 496 NLWVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLVTP------DVLE---KEKQLYD 344
L + + G + VS++N RLE+ + + P DV+ + K D
Sbjct: 227 MLTLLAARAAGATQLFVSDLNDARLELARNVIRDVITINPKRDNVGDVVRSATEGKVGCD 286
Query: 343 VIIDCTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIG 185
V I+C G ++ + +R G V G P H+ I+ FQ+ ++L I G
Sbjct: 287 VAIECVGNEHALKACVDAVRKQGVVVQTGLHP--HENPIDWFQVTFRDLEIKG 337
>UniRef50_A1SCW8 Cluster: Alcohol dehydrogenase, zinc-binding domain
protein; n=1; Nocardioides sp. JS614|Rep: Alcohol
dehydrogenase, zinc-binding domain protein -
Nocardioides sp. (strain BAA-499 / JS614)
Length = 338
Score = 69.7 bits (163), Expect = 8e-11
Identities = 57/221 (25%), Positives = 87/221 (39%), Gaps = 5/221 (2%)
Frame = -1
Query: 796 GQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGGWAQYVKVPQDQVYLLPDG 617
G++V +DP C +C+ CR G C G+ DGG + + P ++ LPD
Sbjct: 77 GRRVAIDPAIPCGVCEQCRAGHGNLCPDVRFAGHAGL--DGGLQERLVWPDHLLFPLPDD 134
Query: 616 VSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNLWVTSLHQLGHRDVTVSEM 437
+S + G L EP H A + G +L+VG G IG L + G V VSE
Sbjct: 135 LSDDAGALLEPLGVAIHAVGVAH-VRPGHDVLVVGGGPIGVLTAAVARRTGAAQVVVSEP 193
Query: 436 NKVRLEIVNKLETGYRLVTPDVLEKEKQL-----YDVIIDCTGVGKVMEISFNYLRHGGK 272
R E + + + +L DV+I+ G + + R G +
Sbjct: 194 LAHRRETARRFGADVAVAPEEASSAVDELTGGRGVDVVIEMAGADDAIGTAVACARPGAR 253
Query: 271 YVLFGCCPPTHQASINPFQIYDKELTIIGVKINPFSFPNAL 149
L G P +S K LT V+ ++P A+
Sbjct: 254 IAL-GGIPSVPLSSFPAAPARRKGLTFAMVRRMHETYPRAI 293
>UniRef50_Q8ES57 Cluster: NADP-dependent alcohol dehydrogenase; n=3;
Bacteria|Rep: NADP-dependent alcohol dehydrogenase -
Oceanobacillus iheyensis
Length = 346
Score = 69.3 bits (162), Expect = 1e-10
Identities = 59/234 (25%), Positives = 103/234 (44%), Gaps = 13/234 (5%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPN-RACSLCDFCRKGKYQYCLTAGINSTVGIWR-- 680
E +G ++DVG + + ++ G +V V +C C+ CR+G+ QYC + + G+ +
Sbjct: 64 EIAGVVSDVGPEVTKYKVGDRVGVGCMVDSCGECENCRRGEEQYCHQGNVQTYGGVDKYG 123
Query: 679 ---DGGWAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLL-----VGEKI 524
GG++ ++ V +D V +PD + + + P C G SPL G+K+
Sbjct: 124 EPTQGGYSTHIVVTEDFVLRIPDNIELD---VAAPLLCA--GITTYSPLNHWNAGPGKKV 178
Query: 523 LIVGAGIIGNLWVTSLHQLGHRDVTVSE-MNKVRLEIVNKLETGYRLVTPDVLEKEKQLY 347
+VG G +G++ V H +G +S +NK + E Y + E +
Sbjct: 179 AVVGMGGLGHMAVKIAHAMGAEVTVLSRTLNKKEDGLEFGAENYYATSEKETFETLAGSF 238
Query: 346 DVIIDCTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIG 185
D+II+ M+ F+ L G V G P S+N F + + G
Sbjct: 239 DLIINTVSAKLDMDAYFSLLNLDGSLVNVGA--PAEPLSVNVFSLIGHRRSFAG 290
>UniRef50_Q8KKS7 Cluster: Putative L-iditol 2-dehydrogenase protein;
n=1; Rhizobium etli CFN 42|Rep: Putative L-iditol
2-dehydrogenase protein - Rhizobium etli (strain CFN 42
/ ATCC 51251)
Length = 344
Score = 68.9 bits (161), Expect = 1e-10
Identities = 63/231 (27%), Positives = 103/231 (44%), Gaps = 10/231 (4%)
Frame = -1
Query: 847 EFSGTITDVGKK--SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRD- 677
E SGTI + R G +V V R C C CR G +C + G+ +
Sbjct: 60 ELSGTIVSLPDDVPDGLRVGDRVAVLLMRRCGQCRACRLGLDNHCAYLNPKARGGVPQGP 119
Query: 676 GGWAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIG 497
GG A +V VP QV+ +P ++ E+ L EP +CVA G +RA G+ + ++G G +G
Sbjct: 120 GGLANFVGVPAYQVFSVPSFLAPERAALVEPVACVARGINRAR-AKAGDTVAVIGGGTMG 178
Query: 496 NLWVTSLHQLGHR----DVTVSEMNKVRLEIVNKLETGYRLVTPDVLEK--EKQLYDVII 335
L L G D V+ V + + + L P ++EK + +D I
Sbjct: 179 LLHSILLTTKGCDVYLFDDDVATHGPVMSTGAHATGSVHSLSDPKLVEKLTDGWGFDCIF 238
Query: 334 DCTGVG-KVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIG 185
CT G + ++ + G + VL+ P + S+ ++ +E+ +IG
Sbjct: 239 -CTRFGVRGIQGAIAAASRGARIVLYQSIPTSDLLSVGANFLHYREIELIG 288
>UniRef50_A5G4J1 Cluster: Alcohol dehydrogenase GroES domain
protein; n=1; Geobacter uraniumreducens Rf4|Rep: Alcohol
dehydrogenase GroES domain protein - Geobacter
uraniumreducens Rf4
Length = 341
Score = 68.9 bits (161), Expect = 1e-10
Identities = 50/187 (26%), Positives = 91/187 (48%), Gaps = 5/187 (2%)
Frame = -1
Query: 805 FRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGGWAQYVKVPQDQVYLL 626
F G++V + + C C FCR+ C + + GI +G A YV V Q ++ L
Sbjct: 81 FSVGERVTGECSIYCGQCQFCREINEDLCTSVKKH---GISANGFAADYVIVNQSSLHSL 137
Query: 625 PD-GVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNLWVTSLHQLGHRDVT 449
D +S E L EP + V G D+A+ + +LI+GAG +G L + + V
Sbjct: 138 KDCEISDESACLIEPAAVVMKGIDKATAHMDPHDVLILGAGTLGILATMIIKSKPNAKVM 197
Query: 448 VSEMNKVRLEIVNKLETGYRLVTPDV----LEKEKQLYDVIIDCTGVGKVMEISFNYLRH 281
+ ++N+ RL+I +L ++V D+ + +D++++ +G V E+ + ++
Sbjct: 198 IVDINETRLQIARELGAD-QVVAMDMKLMPAHVGRGSFDLVVETSGFSDVGEVINHTVKP 256
Query: 280 GGKYVLF 260
GG + F
Sbjct: 257 GGSVLFF 263
>UniRef50_A3S6P0 Cluster: L-threonine 3-dehydrogenase; n=2;
Bacteria|Rep: L-threonine 3-dehydrogenase -
Prochlorococcus marinus str. MIT 9211
Length = 379
Score = 68.9 bits (161), Expect = 1e-10
Identities = 63/231 (27%), Positives = 108/231 (46%), Gaps = 9/231 (3%)
Frame = -1
Query: 847 EFSGTITDVGKKSVFRN-GQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
EF+G I ++G+ + GQ+ + + + R GK+ L G +G+ G
Sbjct: 101 EFAGEIVEIGRDVTGLSIGQRCSGEGHLIGTDSRQSRAGKFH--LDPGTRG-IGVNEQGA 157
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
+AQY+++P V LP + E G + +P H S L+GE +LI GAG IG +
Sbjct: 158 FAQYLRLPAFNVVPLPASIPDEIGAILDPLGNAVH--TALSFDLLGEDVLITGAGPIGIM 215
Query: 490 WVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLV------TPDVLEK--EKQLYDVII 335
G R+V ++++N RL++ + R V DV+ + K+ +DV +
Sbjct: 216 AAAVARHAGARNVVITDINPDRLKLAEHVVPTVRAVDVRNEALEDVIHELGMKEGFDVGL 275
Query: 334 DCTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIGV 182
+ +G ++ L GGK L G P ++ ++ +I K +TI GV
Sbjct: 276 EMSGNQVALDQMVESLVMGGKIALLGI--PPGKSPVDWSRIVFKAITIKGV 324
>UniRef50_A3Q0B4 Cluster: Alcohol dehydrogenase GroES domain
protein; n=4; Mycobacterium|Rep: Alcohol dehydrogenase
GroES domain protein - Mycobacterium sp. (strain JLS)
Length = 347
Score = 68.9 bits (161), Expect = 1e-10
Identities = 53/213 (24%), Positives = 91/213 (42%), Gaps = 9/213 (4%)
Frame = -1
Query: 796 GQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGGWAQYVKVPQDQVYLLPDG 617
G +V ++PN AC C CR G+Y C + G G A +P D+V LPD
Sbjct: 84 GTRVTIEPNLACGHCTQCRAGRYNICRELLV---FGCQTAGALADSFTIPVDRVVALPDE 140
Query: 616 VSTEQGGLCEPYSCVAHGYDRASPL---LVGEKILIVGAGIIGNLWVTSLHQLGHRDVTV 446
+ L EP + H RA+ L L ++++GAG IG + + G R V
Sbjct: 141 LDDRHAILIEPLATPVHTVRRAAGLVGDLRDRAVVVIGAGPIGLFTLLAARHAGARVVVA 200
Query: 445 S--EMNKVRLEIVNKLETGYRLVTPDVLEKEKQLYD----VIIDCTGVGKVMEISFNYLR 284
E + R E + + + + D + ++L V++DC + ++ + +
Sbjct: 201 DLLESKRARAERLGAVGS-FDPTGDDAVATAQRLLGGPAAVVVDCVSRESTVALAVDLVD 259
Query: 283 HGGKYVLFGCCPPTHQASINPFQIYDKELTIIG 185
GG ++ G + + Q D+EL ++G
Sbjct: 260 KGGAVMIVGVAEGSTPVPLGLIQ--DRELALVG 290
>UniRef50_A1WNS6 Cluster: Alcohol dehydrogenase GroES domain
protein; n=1; Verminephrobacter eiseniae EF01-2|Rep:
Alcohol dehydrogenase GroES domain protein -
Verminephrobacter eiseniae (strain EF01-2)
Length = 345
Score = 68.9 bits (161), Expect = 1e-10
Identities = 38/122 (31%), Positives = 61/122 (50%), Gaps = 3/122 (2%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIW--RD 677
E SG + ++G + + GQ+V ++P+R+C +C FCR G +C + W
Sbjct: 63 EASGQVLELGAQVQGLQPGQRVALNPSRSCGVCRFCRAGAANHCENVHFFGSASKWPHMQ 122
Query: 676 GGWAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIG 497
G + V + Q +PD +S E EP + H +A LL G+ +++VGAG IG
Sbjct: 123 GAMREQVVLDAAQCIAVPDALSYEVAAFGEPLAVALHAVRQAGSLL-GKSVMVVGAGPIG 181
Query: 496 NL 491
L
Sbjct: 182 AL 183
>UniRef50_A3GIE9 Cluster: Sorbitol dehydrogenase; n=2;
Saccharomycetaceae|Rep: Sorbitol dehydrogenase - Pichia
stipitis (Yeast)
Length = 381
Score = 68.9 bits (161), Expect = 1e-10
Identities = 56/219 (25%), Positives = 89/219 (40%), Gaps = 22/219 (10%)
Frame = -1
Query: 847 EFSGTITDVGKKSV--FRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWR-- 680
E SG I +G + F G KV ++P C +C C G CL G+
Sbjct: 76 ECSGEIIHIGSEVTEDFEIGNKVAIEPQLPCGICFLCTNGNMNLCLNVDFMGMPGMPGRL 135
Query: 679 ---DGGWAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGA 509
G +Y + VY LPD V+ E+G L E S HG +A L +G+ I G
Sbjct: 136 PSIHGSIQRYKTLDPRFVYKLPDNVTYEEGALVEVLSVGYHGIQKAGGLELGKPCAIAGC 195
Query: 508 GIIGNLWVTSLHQLGHRDVTVSEMNKVRLEIVNKLETG---YRLVT----PDVLEKEKQL 350
G IG + G + V+++++ +L L Y++ T + E ++L
Sbjct: 196 GPIGLATLILAEAAGAYPIVVTDVSQEKLNFAKSLVPSVYTYKVQTNLSPKESAENVRKL 255
Query: 349 Y--------DVIIDCTGVGKVMEISFNYLRHGGKYVLFG 257
+ V+++CTGV + +R G + G
Sbjct: 256 FGKTEYEMPSVVLECTGVASSINTCAYIVRRKGCLTILG 294
>UniRef50_A0V2V9 Cluster: Alcohol dehydrogenase GroES-like; n=1;
Clostridium cellulolyticum H10|Rep: Alcohol
dehydrogenase GroES-like - Clostridium cellulolyticum
H10
Length = 356
Score = 68.5 bits (160), Expect = 2e-10
Identities = 41/149 (27%), Positives = 71/149 (47%), Gaps = 1/149 (0%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
EFSG + +VG K + G +V P C CD+C+ G+ +T G DG
Sbjct: 64 EFSGEVVEVGTKVKNAKVGDRVTAMPLVNCKECDYCKIGQ---AITCDNYDYYGSRIDGA 120
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
A+Y+ V ++ + +PD VS + + +P S H R + + G+ ++ G G IG +
Sbjct: 121 MAEYIVVSEENIIHIPDNVSYYEAAMTDPVSVALHAV-RKAEIEAGQTAVVFGLGAIGFI 179
Query: 490 WVTSLHQLGHRDVTVSEMNKVRLEIVNKL 404
+ L +G V ++ +L++ KL
Sbjct: 180 TIQWLKHMGCHKVIAVDIIDEKLDMAKKL 208
>UniRef50_A1CNK3 Cluster: Xylitol dehydrogenase XdhB, putative;
n=19; Ascomycota|Rep: Xylitol dehydrogenase XdhB,
putative - Aspergillus clavatus
Length = 386
Score = 68.5 bits (160), Expect = 2e-10
Identities = 50/179 (27%), Positives = 83/179 (46%), Gaps = 1/179 (0%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
E +G + V + + G +V ++PN C+ C+ C G+Y C ST + DG
Sbjct: 81 ESAGQVIAVASDVTTLKPGDRVAIEPNIICNECEPCLTGRYNGCEKVAFLSTPPV--DGL 138
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
+YV P + + D +S E G L EP S +R S L +G+ LI GAG IG +
Sbjct: 139 LRRYVNHPAIWCHKIGD-MSFEDGALLEPLSVSLAAIER-SGLRLGDPCLITGAGPIGLI 196
Query: 490 WVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLVTPDVLEKEKQLYDVIIDCTGVGK 314
+ S G + ++++++ RLE L R + + +Q + II+ G+
Sbjct: 197 TLLSARAAGATPIVITDIDEGRLEFAKSLVPEVRTYKVQIGQSAEQNAEGIINVFNDGQ 255
>UniRef50_Q8ZUP0 Cluster: Alcohol dehydrogenase; n=2;
Pyrobaculum|Rep: Alcohol dehydrogenase - Pyrobaculum
aerophilum
Length = 331
Score = 68.5 bits (160), Expect = 2e-10
Identities = 59/223 (26%), Positives = 94/223 (42%), Gaps = 2/223 (0%)
Frame = -1
Query: 847 EFSGTITDVGKKSV-FRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
EF+G + + G G VVV C C C G Q C G +GI GG
Sbjct: 62 EFAGVVEEAGPGVTGVSRGDPVVVYNRLYCGHCRQCLTGWTQMCEVTG-GGIIGIVTQGG 120
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGA-GIIGN 494
+A+Y VP + ++ + A + + GEK+ +VGA G +G
Sbjct: 121 YAEYAVVPAKNA--VATRADLKEAATLPIGALTAWNMAYRASISPGEKVAVVGATGNVGI 178
Query: 493 LWVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLVTPDVLEKEKQLYDVIIDCTGVGK 314
V LG +S K ++E + K ++TPD K +DV++D TG
Sbjct: 179 YAVQFAKLLGGEVYAISR-RKAKVESILKSAGADAVLTPDE-AKSAAPFDVVLDPTGSAS 236
Query: 313 VMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIG 185
++SF L GG+YV G + ++ ++Y ++ +IG
Sbjct: 237 -WDLSFGVLGRGGRYVTAGALTGA-EVRLDLRRLYGMQILVIG 277
>UniRef50_A3MWI2 Cluster: Alcohol dehydrogenase GroES domain
protein; n=4; Thermoprotei|Rep: Alcohol dehydrogenase
GroES domain protein - Pyrobaculum calidifontis (strain
JCM 11548 / VA1)
Length = 345
Score = 68.5 bits (160), Expect = 2e-10
Identities = 55/210 (26%), Positives = 93/210 (44%)
Frame = -1
Query: 796 GQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGGWAQYVKVPQDQVYLLPDG 617
G++VV + N CD+CR G Y +C T+GI DGG A++ P +++ DG
Sbjct: 101 GRRVVSEINFPDWSCDYCRSGLYTHC---PYKRTLGIDFDGGMAEFFAAPPTALHVF-DG 156
Query: 616 VSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNLWVTSLHQLGHRDVTVSEM 437
E G EP + V + + P+ G+K+ ++G G + L + LG S +
Sbjct: 157 -PPELGIFVEPLAAVLNAF-AIRPIRPGDKVAVIGTGNVAQLAAQAARALG-----ASRV 209
Query: 436 NKVRLEIVNKLETGYRLVTPDVLEKEKQLYDVIIDCTGVGKVMEISFNYLRHGGKYVLFG 257
+ V K T + V V E + YDV+ + +G +E++ + G V+
Sbjct: 210 DGVVRRGSRKAATLAKFVDAVVEEPAESAYDVVFEASGDPSALELAVRLAKPRG--VVHL 267
Query: 256 CCPPTHQASINPFQIYDKELTIIGVKINPF 167
P A+ N KE+ ++G + F
Sbjct: 268 KSTPGLPATFNATYFVVKEVAVVGSRCGTF 297
>UniRef50_Q6L743 Cluster: 2-deoxy-scyllo-inosamine dehydrogenase;
n=9; Actinomycetales|Rep: 2-deoxy-scyllo-inosamine
dehydrogenase - Streptomyces kanamyceticus
Length = 343
Score = 68.5 bits (160), Expect = 2e-10
Identities = 69/272 (25%), Positives = 120/272 (44%), Gaps = 9/272 (3%)
Frame = -1
Query: 847 EFSGTITDVGKKSVFRN---GQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRD 677
E+SGT+ ++ + G+ VV D AC C C +G C +G +D
Sbjct: 60 EWSGTVVEINGANGHDQSLVGKNVVGDLTCACGNCAACGRGTPVLCENL---QELGFTKD 116
Query: 676 GGWAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIG 497
G A+Y+ +P D + LPD +S EP + + A + G+++ ++GAG IG
Sbjct: 117 GACAEYMTIPVDNLRPLPDALSLRSACQVEPLAVALNAVSIAG-VAPGDRVAVMGAGGIG 175
Query: 496 NLWVTSLHQLGHRDVTVSEMNKVRLEIVNKL-ETGYRLVTP----DVLEKEKQLY-DVII 335
+ + LG VSE R + +L T P +++ + +L DV++
Sbjct: 176 LMLMQVARHLGGEVTVVSEPVAERRAVAGQLGATELCSAEPGQLAELVARRPELTPDVVL 235
Query: 334 DCTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIGVKINPFSFPN 155
+ +G ++ + +R GG+ L G ++P I K LT+ G F +
Sbjct: 236 EASGYPAALQEAIEVVRPGGRIGLIG-YRVEETGPMSPQHIAVKALTLRGSLGPGGRFDD 294
Query: 154 ALGWLKAMGNRYVNYEKLGVKTYALSEYESAL 59
A+ L A G+ + E L + L++Y +AL
Sbjct: 295 AVE-LLAKGDD-IAVEPLLSHEFGLADYATAL 324
>UniRef50_Q701X1 Cluster: Putative zinc dependent alcohol
dehydrogenase; n=1; uncultured crenarchaeote|Rep:
Putative zinc dependent alcohol dehydrogenase -
uncultured crenarchaeote
Length = 341
Score = 68.1 bits (159), Expect = 3e-10
Identities = 62/216 (28%), Positives = 95/216 (43%), Gaps = 9/216 (4%)
Frame = -1
Query: 796 GQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGGWAQYVKVPQDQVYLLPDG 617
G +V+V P C+ CD CR G C I + + +GG+A+YV VP+ + LP
Sbjct: 80 GSRVLVYPGICCNDCDNCRNGTETLCRDFSIIGGLSKY-NGGYAEYVTVPKTNIISLPRE 138
Query: 616 VSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGA-GIIGNLWVTSLHQLGHRDV-TVS 443
+S EQ A + L + +LI GA G +G + LG R + T+S
Sbjct: 139 ISDEQAATLSISYLTAWNIIKKLHLKENDTVLIYGASGGLGMAMIQISKALGIRTISTIS 198
Query: 442 EMNKVRLEIVNKLETGY---RLVTPDVLEKEKQL----YDVIIDCTGVGKVMEISFNYLR 284
+ +K L + + Y R LE EK D ++D G K + S N +R
Sbjct: 199 DDSK--LNFAYDIGSDYVINRKKKEIALEIEKITRGIGVDAVVDNAG-QKTLNTSINSVR 255
Query: 283 HGGKYVLFGCCPPTHQASINPFQIYDKELTIIGVKI 176
GGK L G + +A+ Y K++ + G+ I
Sbjct: 256 KGGKIALCGTTSGS-EANFQIRTFYSKQIQLFGILI 290
>UniRef50_P77539 Cluster: Uncharacterized zinc-type alcohol
dehydrogenase-like protein ydjL; n=15; Bacteria|Rep:
Uncharacterized zinc-type alcohol dehydrogenase-like
protein ydjL - Escherichia coli (strain K12)
Length = 358
Score = 68.1 bits (159), Expect = 3e-10
Identities = 65/255 (25%), Positives = 119/255 (46%), Gaps = 22/255 (8%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPN-RACSLCDFCRKGKYQYCLTAGINSTV--GIWR 680
EF+G I VG+K ++ GQ+VV D + C +C C +G + C T +N + W
Sbjct: 62 EFAGCIAQVGEKVKDWKVGQRVVSDNSGHVCGVCPACEQGDF-LCCTEKVNLGLDNNTW- 119
Query: 679 DGGWAQYVKVPQD-------QVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKIL 521
GG+++Y VP + ++ +PDGV E + +P + S L G+ ++
Sbjct: 120 GGGFSKYCLVPGEILKIHRHALWEIPDGVDYEDAAVLDPICNAYKSIAQQSKFLPGQDVV 179
Query: 520 IVGAGIIGNLWVTSLHQLGHRDVTVSEMNK---VRLEIVNKLETGYRL--VTPDVLEKEK 356
++G G +G V +G ++ V + + VR + +L + T DV+ + +
Sbjct: 180 VIGTGPLGLFSVQMARIMGAVNIVVVGLQEDVAVRFPVAKELGATAVVNGSTEDVVARCQ 239
Query: 355 QL-----YDVIIDCTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTI 191
Q+ ++I+C+G ++ + LR G+ V G SIN ++K +I
Sbjct: 240 QICGKDNLGLVIECSGANIALKQAIEMLRPNGEVVRVGMGFKPLDFSINDITAWNK--SI 297
Query: 190 IG-VKINPFSFPNAL 149
IG + + S+ NA+
Sbjct: 298 IGHMAYDSTSWRNAI 312
>UniRef50_A6X5V4 Cluster: Alcohol dehydrogenase zinc-binding domain
protein; n=1; Ochrobactrum anthropi ATCC 49188|Rep:
Alcohol dehydrogenase zinc-binding domain protein -
Ochrobactrum anthropi (strain ATCC 49188 / DSM 6882 /
NCTC 12168)
Length = 338
Score = 67.7 bits (158), Expect = 3e-10
Identities = 68/274 (24%), Positives = 124/274 (45%), Gaps = 11/274 (4%)
Frame = -1
Query: 847 EFSGTITDVGK--KSVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDG 674
E G I + G+ + + G++V+V P C C CRKG+ C N T+G+ ++G
Sbjct: 61 EIGGEIMETGEGVSAAYVKGKRVIVLPYTNCGECSSCRKGRLNAC---RYNKTLGVQQNG 117
Query: 673 GWAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGN 494
G A + +P +++ +L + +S L EP S H +R + G+ + ++G G+IG
Sbjct: 118 GLADQIVLPAEKL-ILNETLSPRHLALVEPLSVGFHAVERGR-VQAGDTVAVLGCGMIGM 175
Query: 493 LWVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLV-TPDVLEKEKQL-----YDVIID 332
+ G + + + + R E+ + + L DV+ K ++L DV +
Sbjct: 176 GVLIGALARGAKVIAIDPSAEKR-ELALQFGATHALPGGEDVVAKVQELTNDDGVDVAFE 234
Query: 331 CTGVGKVMEISFNYLRHGGK--YVLFGCCPPTHQASINPFQIYDKELTIIGVKINPFS-F 161
G+ + + G+ YV + P T+Q F + KEL I+G + + F
Sbjct: 235 AVGLPITFTQAVDLAGFAGRVVYVGYSKAPVTYQTQF--FNL--KELDIMGSRNATLTDF 290
Query: 160 PNALGWLKAMGNRYVNYEKLGVKTYALSEYESAL 59
+ L+ +G + +KL K + E E+AL
Sbjct: 291 EAVIAHLEKLG---TDADKLISKVFPFDEAEAAL 321
>UniRef50_Q0UBF8 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 288
Score = 67.7 bits (158), Expect = 3e-10
Identities = 43/149 (28%), Positives = 74/149 (49%), Gaps = 10/149 (6%)
Frame = -1
Query: 676 GGWAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIG 497
GG+A+Y + P QV+ + D E L EP +C HG +R + VG ++L+ G G G
Sbjct: 122 GGFAEYCRYPARQVHPIGDLPDLE-AILVEPAACATHGIERMQ-IEVGSRVLLFGCGPTG 179
Query: 496 NLWVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLVTPDVLEKEKQL----------Y 347
L + G +T++ +L++ +L+ VT E Q+ +
Sbjct: 180 ILLAQLVKMNGAAHLTIASKGGPKLDLARQLQIADEYVTISDTEAHVQMKALAASNPHGF 239
Query: 346 DVIIDCTGVGKVMEISFNYLRHGGKYVLF 260
D++I+ TG V+E S +++R GGK V++
Sbjct: 240 DIVIEATGSPTVLESSLDFVRKGGKLVVY 268
>UniRef50_A0RV95 Cluster: L-iditol 2-dehydrogenase/threonine
dehydrogenase; n=2; Thermoprotei|Rep: L-iditol
2-dehydrogenase/threonine dehydrogenase - Cenarchaeum
symbiosum
Length = 359
Score = 67.7 bits (158), Expect = 3e-10
Identities = 70/282 (24%), Positives = 115/282 (40%), Gaps = 13/282 (4%)
Frame = -1
Query: 847 EFSGTITDVGKKSVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGGW 668
E +GT+ + G +V + C C +C +G C T S + G
Sbjct: 75 EPAGTVVQ-SRAGGISGGDRVFTHHHVPCYSCHYCTRGSETMC-TEYSKSNLS---PCGL 129
Query: 667 AQYVKVPQDQVY-----LLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGI 503
AQ VP+ + LP+ ++ E L EP +C + R +P+ G+ I I+G G
Sbjct: 130 AQRYVVPRHNIMHGGIIRLPEKITFEDAALIEPLACCIRAW-RKAPISEGDAIGIIGVGA 188
Query: 502 IGNLWVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRL--VTPDVLEK-----EKQLYD 344
G + +G V + N RLE K G + PD ++K E + D
Sbjct: 189 TGMMHAMLAKSMGASKVFCIDTNPFRLEFARKCNVGEPIGATDPDRMDKILDGTENRGVD 248
Query: 343 VIIDCTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQA-SINPFQIYDKELTIIGVKINPF 167
V + TG ++ +R GG V+FG P T A +++ +Y +E+T+
Sbjct: 249 VAMVATGNIGALQEGIQMVRKGGTAVMFG-VPSTGAAMNLDMAGLYSREVTL--ASSYAA 305
Query: 166 SFPNALGWLKAMGNRYVNYEKLGVKTYALSEYESALKDLRAG 41
S + LK M + ++ L Y L + + A + R G
Sbjct: 306 SDRDTREALKLMSSGGIDVSPLITHRYPLEDSQRAFEHARGG 347
>UniRef50_A2UF68 Cluster: Alcohol dehydrogenase GroES domain
protein; n=10; Proteobacteria|Rep: Alcohol dehydrogenase
GroES domain protein - Escherichia coli B
Length = 336
Score = 67.3 bits (157), Expect = 5e-10
Identities = 63/240 (26%), Positives = 105/240 (43%), Gaps = 4/240 (1%)
Frame = -1
Query: 847 EFSGTITDVGK--KSVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDG 674
E + +T+VG K+V + G VVVDP AC C C+ G++ C V +R
Sbjct: 65 EIAARVTEVGSDVKNV-QPGDHVVVDPIMACMECRACKAGRFNLCEP----PQVAGFRAP 119
Query: 673 GWA--QYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGII 500
G+A Q++ VP ++ P + + EP +C H +R P E +L++GAG I
Sbjct: 120 GFARSQHI-VPARNCHVAPASLPLKVLAFAEPAACARHCVNR-MPKASLESVLVIGAGTI 177
Query: 499 GNLWVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLVTPDVLEKEKQLYDVIIDCTGV 320
G V +L +G +TV E + + + KL + P L + + + ID
Sbjct: 178 GLSIVQALRIMGAGKITVIEPDAAKRALALKLGAA-EVWAPGELAADVR-FTGAIDVVAA 235
Query: 319 GKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIGVKINPFSFPNALGWL 140
+ + + GG V G + + Q ++++L G+ I P F + WL
Sbjct: 236 QATLNDACTRVYAGGTVVCMGVPSGPREIPLPMMQRFERDLLNSGMYI-PEDFDAVIEWL 294
>UniRef50_A2R610 Cluster: Catalytic activity:; n=5;
Trichocomaceae|Rep: Catalytic activity: - Aspergillus
niger
Length = 356
Score = 67.3 bits (157), Expect = 5e-10
Identities = 62/230 (26%), Positives = 99/230 (43%), Gaps = 9/230 (3%)
Frame = -1
Query: 847 EFSGTITDVGK-KSVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
EFSGTI +VG+ + + G V + PN C C G C G G GG
Sbjct: 71 EFSGTIIEVGEGVTRLQVGDNVAIKPNLFDGGCAACLGGWVNCCDNLGFVGFSG--SAGG 128
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRAS-PLLVGEKILIVGAGIIGN 494
+ YV V +D+ LP+G + G L EP + H +R+S L+VGAG IG
Sbjct: 129 LSDYVVVKEDRAVRLPEGFDLDLGALVEPLTVAWHAVNRSSIQNDHARTALVVGAGPIGL 188
Query: 493 LWVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRL--VTPDVLEKEKQL-----YDVII 335
+ L G V V E++ R E+ + L L T DV+ + + D+
Sbjct: 189 AVLLVLKARGIESVVVVEVSSQRRELASSLGATRVLDPRTADVVGTVRAMTGNAGADIAF 248
Query: 334 DCTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIG 185
+C+ V ++ + +R G + + + +I+ F + E ++G
Sbjct: 249 ECSAVQAGLDTALKGIRARGTMTILSLW--SEKPAIDAFDVVLGEKHVVG 296
>UniRef50_Q89IR8 Cluster: Bll5566 protein; n=2; Rhizobiales|Rep:
Bll5566 protein - Bradyrhizobium japonicum
Length = 434
Score = 66.9 bits (156), Expect = 6e-10
Identities = 60/233 (25%), Positives = 100/233 (42%), Gaps = 29/233 (12%)
Frame = -1
Query: 796 GQKVVVDPNRACSLCDFC--RKGKYQYCLTA-------GINSTVGIWRDGGWAQYVKV-- 650
G KV++ P C C +C CLT G + +W GGWA+YV V
Sbjct: 140 GSKVMIPPLMPCGRCYYCIHYPQTANKCLTPVYYGRYLGFDKAPHMW--GGWAEYVYVDL 197
Query: 649 ---PQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRAS---PLLVGEKILIVGAGIIGNLW 488
P ++Y LPD +S G L EP + ++RAS G+ ++I G+G IG L
Sbjct: 198 DMLPGTKIYKLPDDMSLRLGALSEPLTSCIRAFNRASRAGGFSWGDTVVIQGSGPIGILA 257
Query: 487 VTSLHQLG-HRDVTVSEMNKVRLEIVNKLETGYRLVTPDVLEKEKQL-----------YD 344
V + ++G R + V + RL++ + + ++ ++++ D
Sbjct: 258 VAAAKEMGAGRVICVGAPEEPRLKLAREFGAEATVNIDELKSPQERIARVREIVGGFGAD 317
Query: 343 VIIDCTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIG 185
+++DC+G LR GG YV G + +I K+L ++G
Sbjct: 318 LVMDCSGHPTAGPEGIEMLRDGGTYVEMGQFTDAGSIETSWHRICTKDLNVLG 370
>UniRef50_Q1IJN0 Cluster: Alcohol dehydrogenase GroES-like; n=1;
Acidobacteria bacterium Ellin345|Rep: Alcohol
dehydrogenase GroES-like - Acidobacteria bacterium
(strain Ellin345)
Length = 350
Score = 66.9 bits (156), Expect = 6e-10
Identities = 50/205 (24%), Positives = 90/205 (43%), Gaps = 8/205 (3%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
EF G + VG + ++ + G V + + C C CR G+ C I +G+ +G
Sbjct: 68 EFCGDVVAVGSEVTLVKEGDFVSAEMHVNCGKCLQCRTGQAHICQHVKI---IGVDANGA 124
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
+A+YV +P+ ++ L + E + +P H + + + I G G IG
Sbjct: 125 FAEYVVIPESNIWKLDPAIPQEYASILDPLGNAVHTVLAGD--IAAKTVAITGCGPIGLF 182
Query: 490 WVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRL------VTPDVLEKEKQL-YDVIID 332
+ G V E+N+ R I K++ + L V VL+ + + DV+++
Sbjct: 183 SIAVAKACGATKVFAIEVNEHRRAIAKKMKADFVLDPTKDNVKQVVLDNTEGVGVDVLLE 242
Query: 331 CTGVGKVMEISFNYLRHGGKYVLFG 257
G +++ F+ LR GG+ L G
Sbjct: 243 MAGRQDAIKLGFSILRLGGRASLLG 267
>UniRef50_A1UG38 Cluster: Alcohol dehydrogenase GroES domain
protein; n=5; Actinomycetales|Rep: Alcohol dehydrogenase
GroES domain protein - Mycobacterium sp. (strain KMS)
Length = 362
Score = 66.9 bits (156), Expect = 6e-10
Identities = 59/252 (23%), Positives = 104/252 (41%), Gaps = 14/252 (5%)
Frame = -1
Query: 847 EFSGTITDVGKKSVFR----NGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWR 680
EF GT+ ++ + R G +VV + C C FC++G+Y C + G R
Sbjct: 77 EFVGTVVELDDDAAQRWGIAVGDRVVSEQIVPCWECRFCKRGQYHMCQP---HDLYGFKR 133
Query: 679 --DGGWAQYVKVPQDQ-VYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGA 509
G A Y+ P + V+ + + EP SC H +RA + + +++ G
Sbjct: 134 RTPGAMASYMVYPAEALVHKVSKDIKPHHAAFAEPLSCSLHAVERAQ-ITFEDTVVVAGC 192
Query: 508 GIIGNLWVTSLHQLGHRDVTVSEMNKVRLEIVNK--LETGYRLVTPDVLEKEKQL----- 350
G IG + V ++ +LE+ K + + D + K+L
Sbjct: 193 GPIGLGMIAGARAKNPMHVIALDLAPDKLELAEKCGADITINIAEQDAVAIVKELTDGYG 252
Query: 349 YDVIIDCTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIGVKINP 170
DV ++ TG + N LR G+YV +G + DKEL ++G + P
Sbjct: 253 ADVYLEGTGHTSAVPQGLNLLRKLGRYVEYGVFGSDVTVDWSIIS-DDKELDVLGAHLGP 311
Query: 169 FSFPNALGWLKA 134
+ +P A+ +++
Sbjct: 312 YCWPAAIKMIES 323
>UniRef50_A7RSK1 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 198
Score = 66.9 bits (156), Expect = 6e-10
Identities = 51/158 (32%), Positives = 75/158 (47%), Gaps = 2/158 (1%)
Frame = -1
Query: 523 LIVGAGIIGNLWVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLVTPDVLEKEKQLYD 344
LI GAG++G LH+ G+ V S+++ RL++V++ G L PD EK D
Sbjct: 25 LIQGAGLLGIYGCALLHEAGYDKVYCSDISSERLKMVSRF-AGIPL-GPDQEHLEKNSID 82
Query: 343 VIIDCTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQAS-INPFQIYDKELTIIGV-KINP 170
+I+ GV +V+ LR GG YVL G P + + QI K LTI GV P
Sbjct: 83 TVIEVCGVRQVLSEGIRVLRPGGTYVLVGMVHPDSRLDMVTAEQIIRKCLTIKGVHNYGP 142
Query: 169 FSFPNALGWLKAMGNRYVNYEKLGVKTYALSEYESALK 56
A+ ++ +++ Y L TY L SA +
Sbjct: 143 LHLDQAVSFIDQTASKF-PYADLFSPTYRLENITSAFE 179
>UniRef50_Q97WA1 Cluster: Alcohol dehydrogenase; n=9; cellular
organisms|Rep: Alcohol dehydrogenase - Sulfolobus
solfataricus
Length = 338
Score = 66.9 bits (156), Expect = 6e-10
Identities = 61/226 (26%), Positives = 96/226 (42%), Gaps = 5/226 (2%)
Frame = -1
Query: 847 EFSGTITDVGKKSVFRN-GQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
E +G + VG N G KVVV CD C G+ C GI S + +GG
Sbjct: 68 ELAGVVEKVGDHVKGLNKGDKVVVYNRVFDGTCDLCLSGREMLCRNGGIMSVI---TNGG 124
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGN- 494
W++Y VP ++ +P+ +S + P + + Y L VG +IV G GN
Sbjct: 125 WSEYFSVPDKNIFKIPESMSWDVAASL-PVAALT-SYHSLKELEVGPNDIIVIFGASGNT 182
Query: 493 -LWVTSL-HQLGHRDVTVSEMNKVRLEIVNKLETGYRLVTPDVLE-KEKQLYDVIIDCTG 323
L+ L + G + VS N ++ E GY V V E ++ DV+I+ G
Sbjct: 183 GLFAVQLAKKFGATVIAVSRKNWLK-EFGADYIVGYDDVVQKVKEITNGKMADVVINSLG 241
Query: 322 VGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIG 185
+ E S L G+ FG + + +N +Y + + ++G
Sbjct: 242 -SSMWENSLQVLGLDGQLAFFGTLTGS-EVKVNLSSLYGRHIKVVG 285
>UniRef50_UPI0000E46CC1 Cluster: PREDICTED: similar to SORD protein;
n=3; Strongylocentrotus purpuratus|Rep: PREDICTED:
similar to SORD protein - Strongylocentrotus purpuratus
Length = 292
Score = 66.5 bits (155), Expect = 8e-10
Identities = 39/116 (33%), Positives = 56/116 (48%), Gaps = 1/116 (0%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
E SGT+ +G G +V ++P C +C CR GKY C +T + DG
Sbjct: 69 EASGTVAALGPGVKHLEVGDRVAIEPGVPCRMCSLCRVGKYNLCRDVQFCATPPV--DGN 126
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGI 503
+QY D + LP VS E+G L EP + + RA + +G K+LI G+ I
Sbjct: 127 LSQYYLHAADFCFKLPSNVSYEEGALVEPLAVALYTCSRAE-VSLGSKVLICGSDI 181
>UniRef50_Q1NX30 Cluster: Zinc-containing alcohol dehydrogenase
superfamily; n=3; Bacteria|Rep: Zinc-containing alcohol
dehydrogenase superfamily - delta proteobacterium MLMS-1
Length = 319
Score = 66.5 bits (155), Expect = 8e-10
Identities = 72/282 (25%), Positives = 125/282 (44%), Gaps = 3/282 (1%)
Frame = -1
Query: 847 EFSGTITDVGKKSVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWR-DGG 671
EF G + + S G++VV + N AC C +C +G ++C +T+GI R DG
Sbjct: 56 EFVGVVEGCAESSWL--GRRVVGEINCACGHCSWCAQGLGRHCPR---RTTLGIDRLDGC 110
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
A+Y +P +Y + G++ E+ L EP + ++ + + E+I+++G G +G L
Sbjct: 111 MAEYCLLPIANLYPVEAGLAAERAVLVEPLAAACEILEQLA-VNGNERIVVLGDGRLGIL 169
Query: 490 --WVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLVTPDVLEKEKQLYDVIIDCTGVG 317
WV + DVT+ + +L L L T EK D++++ TG G
Sbjct: 170 CAWVLA---TAADDVTLVGRHPEKL----ALAAWRGLKTLPAGEKPPAGADIVVEATGSG 222
Query: 316 KVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIGVKINPFSFPNALGWLK 137
+ + R G VL + + P I E+T++G + F+ +AL L
Sbjct: 223 AGLSQALALCRPRGTVVLKSTVASQGELELAPLVI--NEITLLGSRCGRFA--DALAMLA 278
Query: 136 AMGNRYVNYEKLGVKTYALSEYESALKDLRAGLVXKAMFKIN 11
+ + +L Y L + E+A +G K + IN
Sbjct: 279 KFPD--MPLARLITHRYPLEQAEAAFARAASGQALKVLLDIN 318
>UniRef50_A7C3H6 Cluster: Zinc-containing alcohol dehydrogenase
superfamily; n=1; Beggiatoa sp. PS|Rep: Zinc-containing
alcohol dehydrogenase superfamily - Beggiatoa sp. PS
Length = 324
Score = 66.5 bits (155), Expect = 8e-10
Identities = 57/228 (25%), Positives = 100/228 (43%)
Frame = -1
Query: 847 EFSGTITDVGKKSVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGGW 668
EF G I + R GQKVV + N C C C +G +C + V RDG +
Sbjct: 57 EFVGEIVQAAEAPE-RVGQKVVGEINVYCGTCQACLRGHSTHCEQRTVLGIVN--RDGAF 113
Query: 667 AQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNLW 488
A+Y+++P + +P+ + E EP + A + +++LIVGAG +G L
Sbjct: 114 AEYLRLPLTNLIPVPNSIPNEIAVFTEPLA-AALEIQAQLTIRPTDRVLIVGAGRLGQLI 172
Query: 487 VTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLVTPDVLEKEKQLYDVIIDCTGVGKVM 308
+L G V+ +K + + N+ ++ D + +D++I+ TG
Sbjct: 173 AQTLVLTGCHLQVVARYDKQQQLLANR-----QIAWIDENVVPTRTFDIVIEATGSVAGF 227
Query: 307 EISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIGVKINPFS 164
++ +R G +L + IN + E+T+IG + PF+
Sbjct: 228 TLARTAVRPRGTIILKSTY--KGEMPINFSSLVVDEITLIGSRCGPFA 273
>UniRef50_A5ZM46 Cluster: Putative uncharacterized protein; n=2;
Ruminococcus|Rep: Putative uncharacterized protein -
Ruminococcus obeum ATCC 29174
Length = 350
Score = 66.5 bits (155), Expect = 8e-10
Identities = 52/182 (28%), Positives = 80/182 (43%), Gaps = 1/182 (0%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
EFSG + +VG+ + + G +V P C CD C+KG + C S +G + G
Sbjct: 59 EFSGDVVEVGEGVTKVKVGDRVSGAPLLPCMKCDDCQKGNFSLCKHY---SFIGSRQQGS 115
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
A YV VP+ V EQG + EP + HG + + GE + I+G G +G
Sbjct: 116 NADYVVVPEQNAVPFDKTVPYEQGAMFEPATVAIHGVFQ-NDYHGGEYVAILGGGTVGMF 174
Query: 490 WVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLVTPDVLEKEKQLYDVIIDCTGVGKV 311
+ G + V V +++ RL + +L + T + EK + I G G V
Sbjct: 175 TMQWTKIFGSKKVVVFDISDERLALAKRLGADEVINTKEEGYMEKAM--AITGGKGYGFV 232
Query: 310 ME 305
E
Sbjct: 233 FE 234
>UniRef50_Q5KPZ2 Cluster: Sorbitol dehydrogenase, putative; n=1;
Filobasidiella neoformans|Rep: Sorbitol dehydrogenase,
putative - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 379
Score = 66.5 bits (155), Expect = 8e-10
Identities = 38/126 (30%), Positives = 58/126 (46%)
Frame = -1
Query: 796 GQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGGWAQYVKVPQDQVYLLPDG 617
G +V ++P C C C+ G Y+ C +T G +Y +P D V+ LP+
Sbjct: 92 GTRVAMEPGVCCRSCANCKAGLYELCPYMSFAATPPTIF-GTLCRYYVLPADLVHPLPES 150
Query: 616 VSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNLWVTSLHQLGHRDVTVSEM 437
VS E G + EP S H + +++ GAG +G L + LG R + ++
Sbjct: 151 VSFEDGAMMEPLSVGVHSVATLGGCKSDQTVIVFGAGPVGLLCMAVAKALGARRIIAVDI 210
Query: 436 NKVRLE 419
NK RLE
Sbjct: 211 NKERLE 216
>UniRef50_Q97BK9 Cluster: Alcohol dehydrogenase [ADH]; n=3;
Thermoplasma|Rep: Alcohol dehydrogenase [ADH] -
Thermoplasma volcanium
Length = 367
Score = 66.5 bits (155), Expect = 8e-10
Identities = 45/149 (30%), Positives = 73/149 (48%), Gaps = 1/149 (0%)
Frame = -1
Query: 847 EFSGTITDVGKKSVFRNGQK-VVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
EF+G + +G+ + K V V+P C C +C+ G Q CL + +G+ G
Sbjct: 60 EFTGKVVKLGEDVDPKLLNKNVAVNPLVTCGKCRYCKTGNRQLCLERKL---IGVDYPGA 116
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
+A+YV VP+ Y + + + L EP + G +A P + ++ L++GAG IG L
Sbjct: 117 FAEYVNVPEYSCYEIKE---IPEASLAEPLATALRGVLQAGPE-IDDRALVIGAGTIGLL 172
Query: 490 WVTSLHQLGHRDVTVSEMNKVRLEIVNKL 404
+G R V ++N RLE V+ L
Sbjct: 173 ATKIFSSVGCRKVVSMDINDNRLEHVDIL 201
>UniRef50_Q5WC08 Cluster: Galactitol-1-phosphate 5-dehydrogenase;
n=1; Bacillus clausii KSM-K16|Rep:
Galactitol-1-phosphate 5-dehydrogenase - Bacillus
clausii (strain KSM-K16)
Length = 352
Score = 66.1 bits (154), Expect = 1e-09
Identities = 59/202 (29%), Positives = 90/202 (44%), Gaps = 5/202 (2%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
EFSGT+ VG G +VVV P F +KG L++ S +G +G
Sbjct: 59 EFSGTVEAVGASVDSVAVGDRVVVAPLLPNKDDPFMQKGSP--ALSSSY-SFLGSRENGA 115
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
A+YV V + + +LP+ V+ + L EP + HG +R L GE + ++GAG IG +
Sbjct: 116 MAEYVVVKAENLLVLPETVTLAEAALIEPLTVAIHGIERI-VLPAGEHVCVLGAGTIGIM 174
Query: 490 WVTSLHQLGHRDVTVSEMNKVRLEIVNKL---ETGYRLVTPDVLEKEKQ-LYDVIIDCTG 323
+ +L G VT ++N +L K+ +T L V K +I+ G
Sbjct: 175 TILALKARGAGKVTAIDINDEKLAFAKKIGADDTINSLKEDPVSYASKHGKPGAVIETAG 234
Query: 322 VGKVMEISFNYLRHGGKYVLFG 257
V E + + GK V G
Sbjct: 235 VPSSQEQAVALVEKKGKIVFVG 256
>UniRef50_A4QH16 Cluster: Putative uncharacterized protein; n=1;
Corynebacterium glutamicum R|Rep: Putative
uncharacterized protein - Corynebacterium glutamicum
(strain R)
Length = 363
Score = 66.1 bits (154), Expect = 1e-09
Identities = 62/250 (24%), Positives = 100/250 (40%), Gaps = 14/250 (5%)
Frame = -1
Query: 847 EFSGTITDVGKKSV---FRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRD 677
E +G IT++ F G +VV+ P C C C G+ C S G + D
Sbjct: 74 EAAGIITEMDPSDEGNGFNVGDRVVICPMFYCGKCYACSVGRVNACKEM---SVYGCYED 130
Query: 676 GGWAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIG 497
G VP ++ +PD + + + EP S R P + GEK+++ GAG IG
Sbjct: 131 GSLVDEQVVPYANLFKIPDSLPLDLAPIVEPISIAMQACKRGRP-VSGEKVIVNGAGPIG 189
Query: 496 NLWVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLVTPDVLEKEKQLYDV-------- 341
L V L G +V V++M + RL++ V Q +V
Sbjct: 190 VLAVRYLKDQG-CEVAVTDMVQSRLDLAKHCGADKTFVVDGGFPNAVQAVEVDTWTDGNG 248
Query: 340 ---IIDCTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIGVKINP 170
IID TGV + + + + G+ V G + ++ KE+ ++G + +
Sbjct: 249 PSLIIDATGVPASLAAAIDLVATAGRVVCVGI--SDRDLVFDMRKLVSKEIDLLGSRNSQ 306
Query: 169 FSFPNALGWL 140
FP + L
Sbjct: 307 NLFPECIALL 316
>UniRef50_A4J9K3 Cluster: Alcohol dehydrogenase GroES domain
protein; n=1; Desulfotomaculum reducens MI-1|Rep:
Alcohol dehydrogenase GroES domain protein -
Desulfotomaculum reducens MI-1
Length = 345
Score = 66.1 bits (154), Expect = 1e-09
Identities = 59/235 (25%), Positives = 97/235 (41%), Gaps = 14/235 (5%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
E +GT+ ++G + G++V V P C +C C G C I +G DGG
Sbjct: 60 EIAGTVVEIGAGVTEVHCGERVQVSPGLPCGVCPNCLTGLNHLCPNIEI---MGFHYDGG 116
Query: 670 WAQYVKVPQDQVYL-----LPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAG 506
+A+YV +P V LPD E L EP +C + + + G+ I+I GAG
Sbjct: 117 FAEYVLIPSKGVKAKVLNKLPDHFPIELAALTEPLACCIN-IQESMDIGSGDTIIIFGAG 175
Query: 505 IIGNLWVTSLHQLGHRDVTVSEMNKVRLEIVNKLETG--YRLVTPDVLEKEKQLYD---- 344
+G L G +++ + ++NK RL + + D ++ ++L D
Sbjct: 176 PVGILNAKLAKLRGAKNIAIFDVNKKRLHQAAGFAFCHLFNPLEQDPVKVVRELTDGTGA 235
Query: 343 -VIIDCTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPF-QIYDKELTIIG 185
+I C + LR GK+ F H S+ + KE+ + G
Sbjct: 236 EAVIPCCPDIAAFRQGLSILRKRGKFGFFSGLVGEHAVSVGELNNFHYKEIRLFG 290
>UniRef50_Q0S6W9 Cluster: Zn-binding dehydrogenase; n=4;
Actinomycetales|Rep: Zn-binding dehydrogenase -
Rhodococcus sp. (strain RHA1)
Length = 347
Score = 65.7 bits (153), Expect = 1e-09
Identities = 57/206 (27%), Positives = 83/206 (40%), Gaps = 9/206 (4%)
Frame = -1
Query: 847 EFSGTITDVGKKSV-FRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
E SGTI +G + G +VV R C C CR+G CL + + DG
Sbjct: 65 EASGTIAKLGAGVTGWSEGDRVVPSAGRPCFGCRNCRRGDLTNCLNIQL---MAFAYDGA 121
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGG-LCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGN 494
WA+Y + +PD V EQ L + S R ++VGE + + G G +G
Sbjct: 122 WAEYTVAQAGGLTRIPDNVPFEQAAILADAVSTPFGAVVRTGKVVVGETVGVWGVGGVGT 181
Query: 493 LWVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLVTPDVLEKEK-------QLYDVII 335
V +G V ++N E +L Y + D KEK ++ DV
Sbjct: 182 HIVQLARLVGAVPVIAFDINPAVRERALELGADYAFDSRDENLKEKVAEATGGRMLDVAF 241
Query: 334 DCTGVGKVMEISFNYLRHGGKYVLFG 257
D G+ E + + L GG+ V G
Sbjct: 242 DAAGLKVTFEQALDCLTVGGRLVAVG 267
>UniRef50_A0JXR0 Cluster: Alcohol dehydrogenase, zinc-binding domain
protein; n=5; Actinobacteria (class)|Rep: Alcohol
dehydrogenase, zinc-binding domain protein -
Arthrobacter sp. (strain FB24)
Length = 355
Score = 65.7 bits (153), Expect = 1e-09
Identities = 48/165 (29%), Positives = 74/165 (44%)
Frame = -1
Query: 679 DGGWAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGII 500
DG +++Y +P + LPDG+S L EP S H RA + G+ L++G+G I
Sbjct: 132 DGAFSRYATLPARMLRPLPDGLSLRTAALAEPASVAWHAVARAGD-VTGKTALVIGSGPI 190
Query: 499 GNLWVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLVTPDVLEKEKQLYDVIIDCTGV 320
G L V L + G R V +M+ LEI + L + DV+I+ +G
Sbjct: 191 GALAVAVLKRAGARRVVAVDMHPKPLEIAQAVGADEVLKADESDAIAAVEADVVIESSGS 250
Query: 319 GKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIG 185
+ + GGK V+ G P Q + I +EL ++G
Sbjct: 251 HHGLASAIKGAVRGGKVVMVGLLPSGPQPVLISLAI-TRELELLG 294
>UniRef50_Q976Y8 Cluster: 344aa long hypothetical alcohol
dehydrogenase; n=1; Sulfolobus tokodaii|Rep: 344aa long
hypothetical alcohol dehydrogenase - Sulfolobus tokodaii
Length = 344
Score = 65.7 bits (153), Expect = 1e-09
Identities = 54/206 (26%), Positives = 101/206 (49%), Gaps = 9/206 (4%)
Frame = -1
Query: 847 EFSGTITDVGKKSV-FRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
E +G I DVG + + F G KV+V+P + C +C+ G+ QYC + +GI +GG
Sbjct: 67 EIAGIIEDVGDEVIGFTKGDKVIVNPWQGEGNCYYCKIGEEQYC---DFPTWLGISTNGG 123
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGA-GIIGN 494
+A+YV + VY + + +S E+ A+ R + L + ++++GA G +G+
Sbjct: 124 YAEYVVSNFNYVYKV-NKLSVEEASPLACAGVTAYRAARLANLTPSKYVMVIGAGGGLGS 182
Query: 493 LWVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLVTPD--VLEK-----EKQLYDVII 335
V + L V ++N+ L++ ++L + Y + D +L++ E + D I+
Sbjct: 183 FGVQIVKALYGSTVIAVDINEEGLKLASRLGSDYVMNAKDQSLLQEILRITEGRGVDAIL 242
Query: 334 DCTGVGKVMEISFNYLRHGGKYVLFG 257
D G + + L G+Y+ G
Sbjct: 243 DFVGSESTTKNYYTILAKLGRYIKVG 268
>UniRef50_Q930C9 Cluster: IdnD L-idonate 5-dehydrogenase; n=4;
Alphaproteobacteria|Rep: IdnD L-idonate 5-dehydrogenase
- Rhizobium meliloti (Sinorhizobium meliloti)
Length = 343
Score = 65.3 bits (152), Expect = 2e-09
Identities = 49/205 (23%), Positives = 88/205 (42%), Gaps = 8/205 (3%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGI-NSTVGIWRDG 674
E SG + +G+ S G V V P+R C CD+C KG +C S +
Sbjct: 63 EVSGHVAALGEGVSDLAIGDLVAVSPSRPCGACDYCLKGLPNHCFHMRFYGSAMPFPHIQ 122
Query: 673 GWAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGN 494
G + V + + +G+S + + EP S H RA +L G+++L+ G G IG
Sbjct: 123 GAFRERLVAKASQCVKAEGLSAGEAAMAEPLSVTLHATRRAGEML-GKRVLVTGCGPIGT 181
Query: 493 LWVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRL-VTPD-----VLEKEKQLYDVIID 332
L + + + G ++ +++++ L + + ++ D + K +DV+ +
Sbjct: 182 LSILAARRAGAAEIVAADLSERALGFARAVGADRTVNLSEDRDGLVPFSENKGTFDVLYE 241
Query: 331 CTGVGKVMEISFNYLRHGGKYVLFG 257
C+G + LR G V G
Sbjct: 242 CSGAQPALVAGIQALRPRGVIVQLG 266
>UniRef50_Q3ZWK2 Cluster: Alcohol dehydrogenase, zinc-containing;
n=3; Dehalococcoides|Rep: Alcohol dehydrogenase,
zinc-containing - Dehalococcoides sp. (strain CBDB1)
Length = 343
Score = 65.3 bits (152), Expect = 2e-09
Identities = 66/260 (25%), Positives = 118/260 (45%), Gaps = 12/260 (4%)
Frame = -1
Query: 805 FRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGGWAQYVKVPQDQ---- 638
F G +V V P AC +C C +G+ C I +G DGG A+Y+ +P +
Sbjct: 73 FEAGCRVQVYPGIACGVCPLCLQGRENLCRKVKI---IGFNYDGGLAEYMALPPESLPVG 129
Query: 637 VYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNLWVTSLHQLGHR 458
+ ++P+ VS E+ L EP + H + G+++L++GAG +G L G
Sbjct: 130 LNIIPEHVSDEEASLAEPLASCIHA-QSVCRVGDGDRVLVLGAGPLGLLQAMLARHNGAE 188
Query: 457 DVTVSEMNKVRL---EIVNK---LETGYRLVTPDVLEKEKQL-YDVIIDCTGVGKVMEIS 299
V V+E+ R+ E+ + ++ G + V ++ DVI+ + +V E+
Sbjct: 189 QVLVAEVLPERVNGAELASPDGVIDLGKTSLKQGVFDQTGGAGVDVILIASSGVEVGELP 248
Query: 298 FNYLRHGGKYVLFGCCPPTH-QASINPFQIYDKELTIIGVKINPFSFPNALGWLKAMGNR 122
F L GG+ F P + I+ ++ +EL I G + NA L+ +G
Sbjct: 249 F-ILSPGGRINFFSGLPKDRSELIIDANAVHYQELVING-SYGSTAADNAEA-LRLIGKG 305
Query: 121 YVNYEKLGVKTYALSEYESA 62
+ ++L + +S+ E+A
Sbjct: 306 IIPVKRLLSRITGISDIEAA 325
>UniRef50_Q1INA4 Cluster: Alcohol dehydrogenase, zinc-binding; n=3;
Bacteria|Rep: Alcohol dehydrogenase, zinc-binding -
Acidobacteria bacterium (strain Ellin345)
Length = 339
Score = 65.3 bits (152), Expect = 2e-09
Identities = 57/236 (24%), Positives = 110/236 (46%), Gaps = 9/236 (3%)
Frame = -1
Query: 847 EFSGTITDVGKKSV-FRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
+ SG + V + + GQ+V++ P RAC C+FC +G++ +C + G DGG
Sbjct: 62 DVSGVVAKVEEYITDLKEGQRVLLAPMRACYHCEFCLRGEHSFCAQFAVR---GTRFDGG 118
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVA-HGYDRASPLLVGEKILIVGAGI-IG 497
+YV VP+ +V +P+ ++ ++ A H + + G+ +L+ GAG +G
Sbjct: 119 DCEYVAVPRVEVIPIPESLTYDEAASVPLVFLTAWHMLVSRAKIKHGQTVLVWGAGSGVG 178
Query: 496 NLWVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRL------VTPDVLEKEKQLYDVII 335
+ +G +T + + +L++ +L Y + V+ +V + K DV+
Sbjct: 179 TAAIQICKLMGCTVITTAGGER-KLDLAWELGADYTIDHYKQKVSDEVKKIVKGGVDVVF 237
Query: 334 DCTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIGVKINPF 167
+ TG K S +R GG V G +A ++ ++ ++LT +G + F
Sbjct: 238 EHTG-EKTWPESLRSMRVGGTLVTCGATTGP-EAKLDLRVLFTRQLTFMGSFMGTF 291
>UniRef50_Q2U7Y6 Cluster: Zn-dependent alcohol dehydrogenases; n=2;
Pezizomycotina|Rep: Zn-dependent alcohol dehydrogenases
- Aspergillus oryzae
Length = 359
Score = 65.3 bits (152), Expect = 2e-09
Identities = 68/238 (28%), Positives = 103/238 (43%), Gaps = 20/238 (8%)
Frame = -1
Query: 838 GTITDVGKKSV--FRNGQKV-VVDPNRACSLCDFCRKGKYQYCLT----AGINSTVGIWR 680
GT+ VGK+S ++ G +V +++ AC C CR + +Y T G
Sbjct: 71 GTVVQVGKESALNWKVGDRVGILNFKNACGNCAGCRGSRKRYGKLDPRFCDHRETGGFKN 130
Query: 679 DGGWAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHG-YDRASPLL-VGEKILIVGAG 506
DG +A Y+ LLPD VS EQG A G ++A P L G+ I +VG G
Sbjct: 131 DGCFAAYMVADSATTILLPDSVSFEQGAPLLCAGATAWGAINKARPFLRTGDMIGVVGIG 190
Query: 505 IIGNLWVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYR----------LVTPDVLEKE- 359
+G L V LG+R V + + L++ + + T +R + +LE+
Sbjct: 191 GLGQLGVQFAKALGYRTVAIDNRD-ASLQLTDDMPTEFRPDFIINSTHDYASEKILERTG 249
Query: 358 KQLYDVIIDCTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIG 185
+ +I+C V S LR GG VL G P + +P I +EL + G
Sbjct: 250 GEGLAAVINCADSIAVNAWSLGLLRIGGVAVLLGLPPEQWRFDTHP--IVFRELVLRG 305
>UniRef50_Q5LQR4 Cluster: L-idonate 5-dehydrogenase; n=13;
Alphaproteobacteria|Rep: L-idonate 5-dehydrogenase -
Silicibacter pomeroyi
Length = 349
Score = 64.9 bits (151), Expect = 2e-09
Identities = 54/256 (21%), Positives = 107/256 (41%), Gaps = 9/256 (3%)
Frame = -1
Query: 796 GQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIW--RDGGWAQYVKVPQDQVYLLP 623
G +V V+P+R C C +C +G +CL + + G + + Q + L
Sbjct: 83 GDRVAVNPSRPCGTCSYCVEGLTTHCLNMRFYGSAMRFPHEQGLFRDKLLTDAAQCHKLS 142
Query: 622 DGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNLWVTSLHQLGHRDVTVS 443
D V+ +G EP + H A + G+++L+ G+G IG L + G ++ V+
Sbjct: 143 DHVTISEGACAEPLAVCLHARHMAGEVR-GKRVLVTGSGPIGVLCAAVAAEAGAAEIVVT 201
Query: 442 EMNKVRLEIVNKLETGYRLVTPDVLEK------EKQLYDVIIDCTGVGKVMEISFNYLRH 281
++ LE+ ++ + +E +K +D++ +C+ + + LR
Sbjct: 202 DLQDAPLEVARRMGATRTVNIAREVEAMAAYAVDKGHFDLVFECSAAAPAIHSAIAALRP 261
Query: 280 GGKYVLFGCCPPTHQASINPFQIYDKELTIIGV-KINPFSFPNALGWLKAMGNRYVNYEK 104
G YV G T + I KEL + G + F A ++ + +R ++
Sbjct: 262 QGTYVQVGV---TGDVPLPVNLIVGKELCLQGTQRFRAEEFAEA---VRLISSRRIDLRA 315
Query: 103 LGVKTYALSEYESALK 56
+ ++ L + E A +
Sbjct: 316 MISGSFPLEQAEEAFR 331
>UniRef50_Q70KF0 Cluster: 2-deoxy-scyllo-inosamine dehydrogenase;
n=1; Micromonospora echinospora|Rep:
2-deoxy-scyllo-inosamine dehydrogenase - Micromonospora
echinospora (Micromonospora purpurea)
Length = 340
Score = 64.9 bits (151), Expect = 2e-09
Identities = 49/182 (26%), Positives = 78/182 (42%), Gaps = 2/182 (1%)
Frame = -1
Query: 796 GQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGGWAQYVKVPQDQVYLLPDG 617
G+ V D C C CR G C +G DGG A YV VP +YLLP+G
Sbjct: 81 GRPVTGDLIVGCQGCGPCRDGLPVMCENL---IEIGFTVDGGCAGYVAVPITNLYLLPEG 137
Query: 616 VSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNLWVTSLHQLGHRDVTVSEM 437
+ EP + H DR + L E++ ++GAG IG L + S G +++
Sbjct: 138 MDLAAASQTEPLAVALHAVDRIN-LRPAERVAVLGAGGIGQLILQSARATGATVTLATDL 196
Query: 436 NKVRLEIVNKLETGYRLVTPDV--LEKEKQLYDVIIDCTGVGKVMEISFNYLRHGGKYVL 263
R +I + + ++ L DV+ + +G + + + + +R GG+ L
Sbjct: 197 VAERRKIAEESGAAAAVHPSELPELTSYADKVDVVFEASGDPESVVRALDLVRPGGRVCL 256
Query: 262 FG 257
G
Sbjct: 257 VG 258
>UniRef50_A4GII5 Cluster: Sorbitol dehydrogenase; n=3; environmental
samples|Rep: Sorbitol dehydrogenase - uncultured marine
bacterium HF10_25F10
Length = 327
Score = 64.5 bits (150), Expect = 3e-09
Identities = 47/182 (25%), Positives = 76/182 (41%), Gaps = 2/182 (1%)
Frame = -1
Query: 796 GQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGGWAQYVKVPQDQVYLLPDG 617
G++V V+P C+ C C G + C G +G+ G +A+ V VP + +L D
Sbjct: 72 GRRVAVNPLMTCNDCPACDSGNHHLC---GTRELIGMRYPGAFAEKVMVPDANLTVLADH 128
Query: 616 VSTEQGGLCEPYSCVAHGYDRASPL--LVGEKILIVGAGIIGNLWVTSLHQLGHRDVTVS 443
+S + L EP + + A+ +I+I+G G IG L L ++
Sbjct: 129 MSFSEAALAEPAAVAVRAVEIAAGTGATADSRIVILGGGAIGVLVAQVLAARSFARPRIA 188
Query: 442 EMNKVRLEIVNKLETGYRLVTPDVLEKEKQLYDVIIDCTGVGKVMEISFNYLRHGGKYVL 263
E N +R ++ + P E D++IDC G+G + R GG V
Sbjct: 189 ETNALRRGMLENIGIAGSY-DPREETPEDGSVDLVIDCVGMGATRAAASAMARPGGVIVH 247
Query: 262 FG 257
G
Sbjct: 248 VG 249
>UniRef50_A1X3A2 Cluster: Putative Zn-dependent dehydrogenase; n=1;
Anaerostipes caccae|Rep: Putative Zn-dependent
dehydrogenase - Anaerostipes caccae
Length = 362
Score = 64.5 bits (150), Expect = 3e-09
Identities = 67/281 (23%), Positives = 121/281 (43%), Gaps = 16/281 (5%)
Frame = -1
Query: 847 EFSGTITDVGKKSVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDG-- 674
E +G I + G K V V N C C+ CRKG+ C+ I S+ + G
Sbjct: 68 EGAGVILETGAKVVELLPGDFVAISNNYCGECEHCRKGEESQCV---IRSSYDLHEGGYK 124
Query: 673 ---GWAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYD--RASPLLVGEKILIVGA 509
G+A+Y V + +S + EP + A G R SP + + ++GA
Sbjct: 125 GRMGFAEYQVRNATAVMKMNPELSPGEAAFLEPLATAAKGIGKLRVSP---QDTVAVIGA 181
Query: 508 GIIGNLWVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLV---TPDVLEKEKQL---- 350
G +G L ++ G R V V+EM + +++ + G+ ++ D +E+ KQ+
Sbjct: 182 GTMGLLNAQAVRACGAR-VIVTEMMEKKIKTAKAM--GFEVIDAGAADPVERVKQMTGGR 238
Query: 349 -YDVIIDCTGVGKVMEISFNYLRH-GGKYVLFGCCPPTHQASINPFQIYDKELTIIGVKI 176
D +I G K E + L+H G+ ++F P + I+ I+ + + I+G +
Sbjct: 239 GADAVIVAVGATKANEQAAAILKHFDGRMLMFAAAYPAPELGISSNDIHYRRMEILGTYL 298
Query: 175 NPFSFPNALGWLKAMGNRYVNYEKLGVKTYALSEYESALKD 53
+ L + + R V+ L +Y L + + A ++
Sbjct: 299 G--DTKDFLEAARLLNQRVVDVRPLIEASYPLEDIQKAFEE 337
>UniRef50_Q8ZU64 Cluster: Alcohol dehydrogenase; n=5;
Thermoprotei|Rep: Alcohol dehydrogenase - Pyrobaculum
aerophilum
Length = 353
Score = 64.5 bits (150), Expect = 3e-09
Identities = 70/286 (24%), Positives = 120/286 (41%), Gaps = 11/286 (3%)
Frame = -1
Query: 847 EFSGTITDVGKKSV----FRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWR 680
E SG + D G + G VV+ C C +C +G+ YC A +
Sbjct: 67 EVSGWVVDFGPRCENPHGLSPGDPVVISWIIPCGKCYWCVRGQENYCPYAAARMPGLVGL 126
Query: 679 DGGWAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGII 500
+GG A+Y+ VP+ V+ +P V + A+ + + + G ++++G G +
Sbjct: 127 NGGHAEYMSVPETAVFPIPKEVDVHTAAVISCAYGTAYRALKEAAVGPGTSLVVIGVGGV 186
Query: 499 GNLWVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRL--VTPDVLEKEKQLY----DVI 338
G V LG R + ++ K LE +L + + D L K + + DV+
Sbjct: 187 GLAAVELASALGARPIIAVDVRKHVLEKAAELGATHLINATNGDPLSKIRDILPQGADVV 246
Query: 337 IDCTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIG-VKINPFSF 161
+ T ++++ +R GG V+ G T + N I + IIG + P +
Sbjct: 247 YE-TKPNPDLKLAVEIVRRGGTIVVTGLGTSTIEIPAN--HIVMNGIRIIGSLGYKPRTD 303
Query: 160 PNALGWLKAMGNRYVNYEKLGVKTYALSEYESALKDLRAGLVXKAM 23
L L A G + ++L YA +E A K+LR GL +A+
Sbjct: 304 IPELLTLAASGK--IKPQRLISHKYAPNEINEAYKNLRIGLHHRAI 347
>UniRef50_Q67N85 Cluster: L-threonine 3-dehydrogenase; n=10;
Bacteria|Rep: L-threonine 3-dehydrogenase -
Symbiobacterium thermophilum
Length = 351
Score = 64.5 bits (150), Expect = 3e-09
Identities = 50/206 (24%), Positives = 90/206 (43%), Gaps = 9/206 (4%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
E +G + VG++ + + G V + + C+ C C G+Y C I +G+ DG
Sbjct: 68 ELAGEVVAVGREVTACKVGDYVSAETHIVCNRCPRCHMGEYHLCENTKI---LGVDTDGA 124
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
+A+YV VP+ +++ + E + EP H + L +LI G G IG +
Sbjct: 125 FAEYVAVPEQNIWVNDKDIPFELQSIQEPLGNAVH--TALNGDLTARSVLITGCGPIGIM 182
Query: 490 WVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLVTP------DVLEKEKQLY--DVII 335
V G V ++N+ RL++ +L L+ P +V+ + Y DV++
Sbjct: 183 SVPVAKMAGAEIVMAMDINEYRLQLAGQLGADV-LINPTKQDPVEVVRSYTRGYGADVVL 241
Query: 334 DCTGVGKVMEISFNYLRHGGKYVLFG 257
+ +G + R+G + L G
Sbjct: 242 EMSGNPTAIRQGLKAARNGARISLLG 267
>UniRef50_Q83GG5 Cluster: Zinc-type alcohol dehydrogenase; n=3;
Actinomycetales|Rep: Zinc-type alcohol dehydrogenase -
Tropheryma whipplei (strain Twist) (Whipple's bacillus)
Length = 357
Score = 64.1 bits (149), Expect = 4e-09
Identities = 71/270 (26%), Positives = 118/270 (43%), Gaps = 26/270 (9%)
Frame = -1
Query: 838 GTITDVGKKSVFRN-GQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG--- 671
G I +VGK + G +V+V P +C +C FCR +CL G + G WR GG
Sbjct: 67 GKIVEVGKDVKSHSVGDRVIVSPMSSCGVCRFCRANNNGHCL--GDSEGPGGWRLGGLIN 124
Query: 670 --WAQYVKVP--QDQVYLLPDGVSTEQGGLCEPYSCVAHGYD-RASPLLVGEKILIVGAG 506
AQ+ ++P + ++ LP G+ + G L H +A + +G + ++G G
Sbjct: 125 GVQAQFARIPLADNSLHKLPSGLDPKVGILVSDVLPTGHEVGAQAGQVTLGSVVAVIGCG 184
Query: 505 IIG-NLWVTSLHQLGHRDVTVSEMNKVRLEIVNKLETG-----YRLVTPDVLEKEKQL-- 350
+G VTSL + + V + + RLE+ KL R D +E K+L
Sbjct: 185 PVGLGAIVTSLLYSPSKVIAV-DADSNRLELARKLGATDTVRVNRERPLDAIEDVKKLTE 243
Query: 349 ----YDVIIDCTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASIN-PFQ-IYDKELTII 188
DV I+ GV ++ GG+ G H A ++ P Q ++DK + +
Sbjct: 244 GGFGVDVAIEAVGVPVTFSMALGIAAPGGRVANIG----VHGAPVDFPLQDLWDKNIAVT 299
Query: 187 GVKINPFSFPNALGWL---KAMGNRYVNYE 107
++ + P L L K +++V +E
Sbjct: 300 LGIVSTHTIPLLLAALSEGKIDASQFVTHE 329
>UniRef50_Q565X2 Cluster: 6-hydroxycylohex-1-ene-1-carboxyl-CoA
dehydrogenase; n=1; uncultured bacterium|Rep:
6-hydroxycylohex-1-ene-1-carboxyl-CoA dehydrogenase -
uncultured bacterium
Length = 340
Score = 64.1 bits (149), Expect = 4e-09
Identities = 57/231 (24%), Positives = 101/231 (43%), Gaps = 10/231 (4%)
Frame = -1
Query: 847 EFSGTITDVGKKSV-FRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
E SG + G + GQ+V++ C C CR+G+ C + +G DG
Sbjct: 62 EASGIVEKAGANVTNVKPGQRVLIPAVLTCGHCPACRQGRENICSNM---TMLGNHFDGA 118
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGG-LCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGN 494
+A+YV VP V LP+ + ++ + + S H + + G+ +++ G G +G
Sbjct: 119 YAEYVAVPAKDVLGLPEAIPLQEASIIADAISTPYHAVKNRAQVKPGDTVVVFGCGGVGI 178
Query: 493 LWVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLVTPDVLEKEKQL-------YDVII 335
V G + V ++N +LE + + V K++ D+ +
Sbjct: 179 NAVQMASAAGGYVIAV-DINPRKLEWAREFGAAKTVDASKVDRVSKEIKKLTGGGADIAM 237
Query: 334 DCTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQA-SINPFQIYDKELTIIG 185
+ G + +E +F +R GG+ + G TH+A SI +I KEL I+G
Sbjct: 238 EVIGNPRTIEQAFECVRVGGRLCVVGY---THEAISIVAGKIMFKELEIVG 285
>UniRef50_A1DBH5 Cluster: Alcohol dehydrogenase; n=3;
Pezizomycotina|Rep: Alcohol dehydrogenase - Neosartorya
fischeri (strain ATCC 1020 / DSM 3700 / NRRL
181)(Aspergillus fischerianus (strain ATCC 1020 / DSM
3700 / NRRL 181))
Length = 386
Score = 64.1 bits (149), Expect = 4e-09
Identities = 36/145 (24%), Positives = 66/145 (45%), Gaps = 2/145 (1%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
E SG + VG S + G + ++P C C C+ G+Y C + G
Sbjct: 75 EASGIVHAVGPSVSTLQPGDHIAIEPGYPCHRCPCCKSGRYNLCPRMKFAAAPPSCH-GT 133
Query: 670 WAQYVKVPQDQVYLLPDG-VSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGN 494
+Y ++P D Y +P G + ++ L EP + H R + G+++++ GAG +G
Sbjct: 134 LTKYFRLPADYCYKIPPGTLGLDEAVLMEPLAVAVHSV-RQVGVRPGDRVVVFGAGTVGL 192
Query: 493 LWVTSLHQLGHRDVTVSEMNKVRLE 419
L + G +++ ++N +LE
Sbjct: 193 LCAAVAREFGAATISMVDLNAAKLE 217
>UniRef50_Q9ZEX7 Cluster: Dehydrogenase; n=1; Thiobacillus sp.|Rep:
Dehydrogenase - Thiobacillus sp
Length = 422
Score = 63.7 bits (148), Expect = 6e-09
Identities = 60/232 (25%), Positives = 102/232 (43%), Gaps = 12/232 (5%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDP--NRACSLCDFCRKGKYQYCLTAGINSTVGIWRD 677
EF+GTI +VG+ S R G++V D N C C FC G +C+ + +R
Sbjct: 138 EFAGTIVEVGEGVSRDRIGKRVTADLFLNAMCGNCQFCISGHAYHCIDKALP-----FRS 192
Query: 676 GGWAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIG 497
GG+A+Y++V + LPD + G L EP + H R + G +++GAG IG
Sbjct: 193 GGFAEYLRVRNAATFDLPDSIDDALGALVEPLAVSTHAI-RLVGVQPGMIGVVIGAGTIG 251
Query: 496 NLWVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLVTPD--------VLEKEKQLYDV 341
+ + G +V V + + E+ + G + PD + E D
Sbjct: 252 LCAIAAALHAGATNVFVVARHAFQGELARAI--GATDILPDDIGSAINRIREVAPHGADF 309
Query: 340 IIDCTGVGK-VMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTII 188
+I+ G G+ ++ + +L G+ + G P + + + KELT +
Sbjct: 310 VIEAVGGGQATIDQATRFLAPRGRVGIVGETGPGIKV-VEAYPALMKELTFL 360
>UniRef50_A6W9X6 Cluster: Alcohol dehydrogenase GroES domain
protein; n=3; Actinomycetales|Rep: Alcohol dehydrogenase
GroES domain protein - Kineococcus radiotolerans
SRS30216
Length = 349
Score = 63.7 bits (148), Expect = 6e-09
Identities = 33/88 (37%), Positives = 49/88 (55%)
Frame = -1
Query: 679 DGGWAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGII 500
DGG++Q+ V DQ+ LP+GV T +G L EP + H RA L G +L+ GAG I
Sbjct: 124 DGGFSQFRTVRSDQLRFLPEGVDTLRGALAEPLAVAMHAVGRAGS-LAGRDVLVNGAGPI 182
Query: 499 GNLWVTSLHQLGHRDVTVSEMNKVRLEI 416
G+L V + G VT ++++ L +
Sbjct: 183 GSLVVAAAVHAGAASVTAADVSPAALRV 210
>UniRef50_Q0LJ45 Cluster: Alcohol dehydrogenase GroES-like; n=1;
Herpetosiphon aurantiacus ATCC 23779|Rep: Alcohol
dehydrogenase GroES-like - Herpetosiphon aurantiacus
ATCC 23779
Length = 344
Score = 63.3 bits (147), Expect = 7e-09
Identities = 53/207 (25%), Positives = 91/207 (43%), Gaps = 10/207 (4%)
Frame = -1
Query: 847 EFSGTITDVGKKSV-FRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
+ +G I +G+ +R GQ+VVV+PN C C++C G+ C G+ +G + GG
Sbjct: 65 DIAGEIAAIGEGVTGWREGQRVVVNPNIWCGACEYCIAGEETLCDRYGV---IGEHQTGG 121
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVA-HGYDRASPLLVGEKILIVGAGIIGN 494
AQY+ VP +Y +P + EQ A + L G+ +LI+GAG G
Sbjct: 122 LAQYIAVPARNLYAIPADYAFEQAAAVPLVWMTAWRALIGQAQLRAGQSVLILGAG--GG 179
Query: 493 LWVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLVTPDVLEKEKQLY--------DVI 338
+ ++ + TV ++ ++ E G V + ++L+ DV+
Sbjct: 180 VASAAIQIARYAGATVYAASRSPEKLARAQELGADYVVRSDGDWGRELWKQTNKRGVDVV 239
Query: 337 IDCTGVGKVMEISFNYLRHGGKYVLFG 257
++ G E S + GG V +G
Sbjct: 240 LENVGAA-TWESSLRSVAKGGTVVTYG 265
>UniRef50_A5V071 Cluster: Alcohol dehydrogenase GroES domain
protein; n=2; Roseiflexus|Rep: Alcohol dehydrogenase
GroES domain protein - Roseiflexus sp. RS-1
Length = 317
Score = 63.3 bits (147), Expect = 7e-09
Identities = 54/212 (25%), Positives = 98/212 (46%), Gaps = 1/212 (0%)
Frame = -1
Query: 796 GQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGI-WRDGGWAQYVKVPQDQVYLLPD 620
GQ+VV + N AC C CR+G +C +T+GI RDG A+ +P ++ +PD
Sbjct: 71 GQRVVGEINAACRSCAVCRRGDESHCPN---RTTLGIDRRDGAMAELFSLPIACLHRVPD 127
Query: 619 GVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNLWVTSLHQLGHRDVTVSE 440
+ EP + + L +++ +VG G +G L V + +L DVT+
Sbjct: 128 RMPDAVAVFTEPVAAALEILQQIH-LHPTDRVAVVGDGKLGLLCVQAA-RLPGCDVTLVG 185
Query: 439 MNKVRLEIVNKLETGYRLVTPDVLEKEKQLYDVIIDCTGVGKVMEISFNYLRHGGKYVLF 260
+ R E ++ L + + ++ E +DV+IDCTG ++ +R G+ V+
Sbjct: 186 RHPERWEFLDGLAI-HAMHVNELDEAHIAGFDVVIDCTGHPHGFGVARRLVRPRGRLVMK 244
Query: 259 GCCPPTHQASINPFQIYDKELTIIGVKINPFS 164
+ ++ + E+ +IG + PF+
Sbjct: 245 STFAAESECNLTMLVV--DEVRLIGSRCGPFA 274
>UniRef50_A1SI74 Cluster: Alcohol dehydrogenase, zinc-binding domain
protein; n=2; Actinomycetales|Rep: Alcohol
dehydrogenase, zinc-binding domain protein -
Nocardioides sp. (strain BAA-499 / JS614)
Length = 395
Score = 63.3 bits (147), Expect = 7e-09
Identities = 59/211 (27%), Positives = 93/211 (44%), Gaps = 31/211 (14%)
Frame = -1
Query: 796 GQKVVVDPNRACSL-----CDFCRKGKYQYC--LTAGINST---VGIWRD--GGWAQYVK 653
G +VVVDP C+ C+ C G C +T G S G D GGW Q +
Sbjct: 103 GTRVVVDPVLGCAARGVEPCEACAAGATNRCARITVGHLSPGLQTGFCHDTGGGWGQQLA 162
Query: 652 VPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNLWVTSLH 473
+ Q++ +P+G S EQ L EP +C H RA + G+++L+ GAG +G +L
Sbjct: 163 AHRSQLHPVPEGFSDEQAILIEPVACAVHTALRAG-VAAGDRVLVSGAGSVGLFATLALR 221
Query: 472 QLGHR-DVTVSEMNKVRLEIVNKLETGYRLVTPDVLEKEK------QL------------ 350
+L ++ V + + E+ +L + +VL + + QL
Sbjct: 222 ELTEAGEIIVVAKHPHQRELARELGATEVVAPGEVLRRVRRSTGAFQLEPEFSTPYLLGG 281
Query: 349 YDVIIDCTGVGKVMEISFNYLRHGGKYVLFG 257
DV +D G + +E + R GG+ VL G
Sbjct: 282 VDVAVDAVGSKQSLESALQATRAGGRVVLSG 312
>UniRef50_Q2UHR2 Cluster: Sorbitol dehydrogenase; n=8;
Ascomycota|Rep: Sorbitol dehydrogenase - Aspergillus
oryzae
Length = 388
Score = 63.3 bits (147), Expect = 7e-09
Identities = 69/282 (24%), Positives = 119/282 (42%), Gaps = 18/282 (6%)
Frame = -1
Query: 847 EFSGTITDVGKKSV-FRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
E +G + G+ R G +V V+P C C C G+Y C G++ G
Sbjct: 94 EAAGVVLKCGEGVTHLRPGDRVAVEPGVPCGDCFLCLDGRYNLCEDV---QFAGVYPYAG 150
Query: 670 WAQYVKV-PQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGN 494
Q K P V+ LPD ++ +G L EP S V G A L +G ++ GAG IG
Sbjct: 151 TIQRYKTHPAKWVHKLPDNLTYAEGALLEPLSVVMRGMSVAG-LQLGRGAVVCGAGPIGL 209
Query: 493 LWVTSLHQLGHRDVTVSEMNKVRLEI------------VNK-LETGYRLVTPDVLEKEKQ 353
+ + + G + +++++ RL VN+ L+ L ++
Sbjct: 210 IALAAARASGAHPIVITDLDASRLAFAKEFVPSCITYQVNRDLDAQGNAKAIRALFGSEE 269
Query: 352 LY--DVIIDCTGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIGVK 179
+ + +++CTGV + + R GG V+ G +A +N L I ++
Sbjct: 270 YFAPETVLECTGVESSVCTAAFTARRGGTVVVIG----VGKAVMNNLPFMHISLAEIDLR 325
Query: 178 -INPFSFPNALGWLKAMGNRYVNYEKLGVKTYALSEYESALK 56
IN + A ++ M ++ ++L T+ L + ESAL+
Sbjct: 326 FINRYRDTWAPA-IQCMSGGILDLKRLVTHTFPLEQAESALQ 366
>UniRef50_Q9KBH6 Cluster: BH1951 protein; n=1; Bacillus
halodurans|Rep: BH1951 protein - Bacillus halodurans
Length = 408
Score = 62.1 bits (144), Expect = 2e-08
Identities = 41/142 (28%), Positives = 66/142 (46%), Gaps = 15/142 (10%)
Frame = -1
Query: 847 EFSGTITDVGKKSV--FRNGQKVVVDPNRACSL------CDFCRKGKYQYC-------LT 713
E GTI+ +KSV + GQ+VV+DP +C + C C G Y C +
Sbjct: 89 EMVGTISKA-RKSVTNLQVGQRVVIDPLLSCEVRGITPVCSECANGNYNLCHHMNDGDIA 147
Query: 712 AGINSTVGIWRDGGWAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVG 533
G+ + G W +Y+ Q QV LP V + G L EP++C H + P
Sbjct: 148 PGLLTGTCKDTGGSWGRYLVAHQSQVISLPSSVDDDNGVLVEPFACALHAVLQNRP-KPS 206
Query: 532 EKILIVGAGIIGNLWVTSLHQL 467
+ + ++G+G+IG + ++ L
Sbjct: 207 DTVFVIGSGVIGICVIAAIRAL 228
>UniRef50_Q987C5 Cluster: Alcohol dehydrogenase; n=4;
Rhizobiales|Rep: Alcohol dehydrogenase - Rhizobium loti
(Mesorhizobium loti)
Length = 341
Score = 62.1 bits (144), Expect = 2e-08
Identities = 47/159 (29%), Positives = 73/159 (45%), Gaps = 1/159 (0%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
E +GT+T +G+ G +VV D C C CR G+ C + G VG DGG
Sbjct: 61 ELTGTVTALGEGVDTVAVGDRVVADSRFWCEECVQCRAGRRHLCASLGF---VGEVCDGG 117
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
+A+ V +P ++++ + + EP + H R P G +L+VG G IG L
Sbjct: 118 FAEQVVLPARLLHVVDAALDERVAAMAEPLAVALHAV-RRLPKTAG-SVLVVGCGPIGGL 175
Query: 490 WVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLVTPD 374
L + V V++ N+ R V ++ TG +V D
Sbjct: 176 AALLLSRSFAGTVLVADRNQARCARVARV-TGATIVDLD 213
>UniRef50_Q8Z6Z4 Cluster: Starvation sensing protein RspB; n=1;
Salmonella typhi|Rep: Starvation sensing protein RspB -
Salmonella typhi
Length = 287
Score = 62.1 bits (144), Expect = 2e-08
Identities = 39/125 (31%), Positives = 63/125 (50%), Gaps = 1/125 (0%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
EF G I VG + R G++V VDP +C C C GK C + + +G+ RDGG
Sbjct: 60 EFFGVIDAVGDNVNRDRIGERVSVDPVISCGHCYPCSVGKPNVCTSLVV---LGVHRDGG 116
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
+++Y P + +PD ++ + EP++ A+ + +P + LI GAG +G
Sbjct: 117 FSEYAVAPARNAHRIPDNIADHHAVMVEPFTIAANVTGQVNP-TEQDVALIYGAGPMGLT 175
Query: 490 WVTSL 476
V +L
Sbjct: 176 TVQAL 180
>UniRef50_Q2LQ73 Cluster: Zinc-binding dehydrogenase; n=2;
Bacteria|Rep: Zinc-binding dehydrogenase - Syntrophus
aciditrophicus (strain SB)
Length = 362
Score = 62.1 bits (144), Expect = 2e-08
Identities = 54/203 (26%), Positives = 84/203 (41%), Gaps = 11/203 (5%)
Frame = -1
Query: 847 EFSGTITDVGKKSVFRN-GQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
EF I +VG N G +VVV C C CR+G + C G S DGG
Sbjct: 74 EFCAEIMEVGPAVKSLNVGDRVVVSCVAFCGECRSCRQGLHARCEKTGFGSFGMNGPDGG 133
Query: 670 WAQYVKVPQDQVYL--LPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIG 497
A+YV++P Y +P+ ++ + C + + GE +++VGAG +G
Sbjct: 134 QAEYVRLPGADRYCFKIPESLTFQDVLFCGDVLSAGYYGAEMGDIQRGETVVVVGAGPVG 193
Query: 496 NLWVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLVTP---DVLEKEKQL-----YDV 341
+ S + + N RL+ K + P V+E + L D
Sbjct: 194 LCAMASARLREPSRIIAVDTNPYRLDAALKAGVADLALNPVKDRVVEIVQGLTDGRGADK 253
Query: 340 IIDCTGVGKVMEISFNYLRHGGK 272
I+C G+ +I+F +R GGK
Sbjct: 254 TIECAGMQTTFDIAFQAVRGGGK 276
>UniRef50_Q0RVL1 Cluster: Zn-dependent alcohol dehydrogenase; n=1;
Rhodococcus sp. RHA1|Rep: Zn-dependent alcohol
dehydrogenase - Rhodococcus sp. (strain RHA1)
Length = 347
Score = 62.1 bits (144), Expect = 2e-08
Identities = 49/186 (26%), Positives = 87/186 (46%), Gaps = 6/186 (3%)
Frame = -1
Query: 847 EFSGTITDVGKKSVFRN-GQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
EF G +VG++ + G++ C C +C++ + + C + T G G
Sbjct: 60 EFCGEAVEVGEEVRGASVGERYTGFSVEFCGQCYWCQRNQQRLCPHLFEHYT-GYGEPGA 118
Query: 670 WAQYVKVPQDQV----YLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGI 503
A+YV + Q Q+ + +P +S E L EP A+ RA P G+ ++++G G+
Sbjct: 119 MAEYVLIRQAQLDQNLFAIPASLSDEAAALAEPLGTAAYSVRRAKPQ-DGDTVVVIGGGM 177
Query: 502 IGNLWVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLVTPDVLE-KEKQLYDVIIDCT 326
IGNL V ++ V V+E++ R E+ R+ +V++ + L D + T
Sbjct: 178 IGNLIVQTVKATVDAKVIVTEVSPERAEL------ALRVGADEVIDARRPDLIDAVRAAT 231
Query: 325 GVGKVM 308
G G+ M
Sbjct: 232 GRGRYM 237
>UniRef50_A0V7I1 Cluster: Alcohol dehydrogenase GroES-like; n=2;
Comamonadaceae|Rep: Alcohol dehydrogenase GroES-like -
Delftia acidovorans SPH-1
Length = 567
Score = 62.1 bits (144), Expect = 2e-08
Identities = 39/122 (31%), Positives = 59/122 (48%), Gaps = 5/122 (4%)
Frame = -1
Query: 847 EFSGTITDVGKKSV-----FRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIW 683
EFSG I +G+ + GQ V V P+ C C C G + C T +G+
Sbjct: 281 EFSGEIAALGEGAENLAPGLTVGQMVAVRPSVTCGRCAACTSGNFDGCTT---RRGIGVL 337
Query: 682 RDGGWAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGI 503
R+GG+A + VP +P GV + L EP + V+H R + + G ++L++G G
Sbjct: 338 RNGGFAPWAAVPLRNCVPVPAGVQGDVAALAEPLT-VSHEAVRTAGVRPGHRVLVLGPGN 396
Query: 502 IG 497
IG
Sbjct: 397 IG 398
>UniRef50_Q07786 Cluster: Sorbitol dehydrogenase 2; n=8;
Saccharomycetales|Rep: Sorbitol dehydrogenase 2 -
Saccharomyces cerevisiae (Baker's yeast)
Length = 357
Score = 62.1 bits (144), Expect = 2e-08
Identities = 40/133 (30%), Positives = 62/133 (46%), Gaps = 1/133 (0%)
Frame = -1
Query: 847 EFSGTITDVGKKSV-FRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
E SG + +VG + G +V ++P D ++G Y C +T I DG
Sbjct: 69 ESSGQVVEVGDAVTRVKVGDRVAIEPGVPSRYSDETKEGSYNLCPHMAFAATPPI--DGT 126
Query: 670 WAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 491
+Y P+D + LP+GVS E+G EP S H ++ + + G K+++ GAG +G L
Sbjct: 127 LVKYYLSPEDFLVKLPEGVSYEEGACVEPLSVGVHS-NKLAGVRFGTKVVVFGAGPVGLL 185
Query: 490 WVTSLHQLGHRDV 452
G DV
Sbjct: 186 TGAVARAFGATDV 198
>UniRef50_P39346 Cluster: L-idonate 5-dehydrogenase; n=17;
Gammaproteobacteria|Rep: L-idonate 5-dehydrogenase -
Escherichia coli (strain K12)
Length = 343
Score = 61.7 bits (143), Expect = 2e-08
Identities = 60/259 (23%), Positives = 102/259 (39%), Gaps = 7/259 (2%)
Frame = -1
Query: 811 SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWR--DGGWAQYVKVPQDQ 638
S GQ V ++P++ C C +C + C + + DGG+ +Y V Q
Sbjct: 77 SELHEGQTVAINPSKPCGHCKYCIEHNENQCTDMRFFGSAMYFPHVDGGFTRYKMVETSQ 136
Query: 637 VYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNLWVTSLHQLGHR 458
P + EP + H +A L G+++ I G G IG L V+++ LG
Sbjct: 137 CVPYPAKADEKVMAFAEPLAVAIHAAHQAGE-LQGKRVFISGVGPIGCLIVSAVKTLGAA 195
Query: 457 DVTVSEMNKVRLEIVNKLETGYRLVTP-----DVLEKEKQLYDVIIDCTGVGKVMEISFN 293
++ ++++ L + ++ LV P D + EK +DV + +G +
Sbjct: 196 EIVCADVSPRSLSLGKEMGADV-LVNPQNDDMDHWKAEKGYFDVSFEVSGHPSSVNTCLE 254
Query: 292 YLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIGVKINPFSFPNALGWLKAMGNRYVN 113
R G V G A + KE+++ G F A+ WL N +N
Sbjct: 255 VTRARGVMVQVGM--GGAMAEFPMMTLIGKEISLRGSFRFTSEFNTAVSWL---ANGVIN 309
Query: 112 YEKLGVKTYALSEYESALK 56
L Y ++ E AL+
Sbjct: 310 PLPLLSAEYPFTDLEEALR 328
>UniRef50_UPI00015BC9A2 Cluster: UPI00015BC9A2 related cluster; n=1;
unknown|Rep: UPI00015BC9A2 UniRef100 entry - unknown
Length = 335
Score = 61.3 bits (142), Expect = 3e-08
Identities = 69/287 (24%), Positives = 120/287 (41%), Gaps = 8/287 (2%)
Frame = -1
Query: 847 EFSGTITDVGK--KSVFRNGQKVVVD-PNRACSLCDFCRKGKYQYCLTAGINSTVGIWRD 677
E +G + VG K+V + G +V + +C +CD+C +G+ C I GI R
Sbjct: 62 EVAGIVEKVGSNVKNV-KEGDRVGMPWLYSSCEICDYCVEGEEPLCPNHEIT---GITRQ 117
Query: 676 GGWAQYVKVPQDQVYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIG 497
GG+A+Y+K P V +PD + + L E ++I G G +G
Sbjct: 118 GGYAEYMKAPSHFVTKIPDKLELSYAAPLFCAGITVYAALVRLNLKPNELVVIQGIGGLG 177
Query: 496 NLWVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLVT--PDVLEKEKQL--YDVIIDC 329
+L + +G + V +S +K + + +L Y + + D +++ K L D I+
Sbjct: 178 HLAIQYAKAMGAKVVALSHSDKEK--VAKELGADYFINSSKQDPVKELKALGGADTILTT 235
Query: 328 TGVGKVMEISFNYLRHGGKYVLFGCCPPTHQASINPFQIYDKELTIIGVKINPFSFPNAL 149
K ++ + L G+ + G +NPF + K + I G I +
Sbjct: 236 VYDSKSIQNLVDALAPKGRLSVVGAA--QEPIYVNPFDLITKRIVITGSAIGGRKLLREM 293
Query: 148 GWLKAMGNRYVNYEKLGVKTYALSEYESALKDLRAG-LVXKAMFKIN 11
A N K ++ Y + AL DLR+G +V + + K N
Sbjct: 294 LEFSAFNN-----IKPIIQEYKFEDVNKALDDLRSGKIVLRGVLKFN 335
>UniRef50_Q89Z65 Cluster: Putative zinc-type alcohol dehydrogenase;
n=6; Bacteria|Rep: Putative zinc-type alcohol
dehydrogenase - Bacteroides thetaiotaomicron
Length = 350
Score = 61.3 bits (142), Expect = 3e-08
Identities = 51/186 (27%), Positives = 79/186 (42%), Gaps = 3/186 (1%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
E G + +VG + + R G +V V+ C C FC G C +G DGG
Sbjct: 61 EMVGVVEEVGAEVTSVRPGDRVTVNVETFCGECFFCHHGYVNNCTDPNGGWALGCRIDGG 120
Query: 670 WAQYVKVP-QDQ-VYLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIG 497
A+YV+VP DQ + +PD VS EQ R S + + IL++GAG G
Sbjct: 121 QAEYVRVPYADQGLNRIPDTVSDEQALFVGDVLATGFWATRISEITEKDTILLIGAGPTG 180
Query: 496 NLWVTSLHQLGHRDVTVSEMNKVRLEIVNKLETGYRLVTPDVLEKEKQLYDVIIDCTGVG 317
+ + + V E + R++ V + + TP E K+ D +G
Sbjct: 181 ICTLLCSMLKNPKRIIVCEKSPERIQFVREHYPDVLITTP---ENCKEFVLQNSDHSGAD 237
Query: 316 KVMEIS 299
V+E++
Sbjct: 238 VVLEVA 243
>UniRef50_A3PJU5 Cluster: Alcohol dehydrogenase GroES domain
protein; n=2; Rhodobacter sphaeroides|Rep: Alcohol
dehydrogenase GroES domain protein - Rhodobacter
sphaeroides (strain ATCC 17029 / ATH 2.4.9)
Length = 364
Score = 61.3 bits (142), Expect = 3e-08
Identities = 53/206 (25%), Positives = 97/206 (47%), Gaps = 9/206 (4%)
Frame = -1
Query: 847 EFSGTITDVGKK-SVFRNGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGG 671
E +G + DVG + + G V+ P R C +C CR G +C N G+ DGG
Sbjct: 72 ENAGWVEDVGSGVTSVKPGDAVICHPLRTCGICLNCRHGHDMHCQN---NLFPGLGLDGG 128
Query: 670 WAQYVKVPQDQVYLLPDGVS-TEQGGLCEPYSCVAHGYDRASPLL-VGEKILIVGAGIIG 497
+A+Y K + + L G++ + + RA+ LL G+ LI+G G +G
Sbjct: 129 FAEYFKTSERSLIKLNTGITPLSVAPMADAGITAYRAAKRAAKLLNPGDWALILGVGGLG 188
Query: 496 NLWVTSLHQL-GHRDVTVSEMNKVRLEIVNKLETGYRLV-TPDVLEKEKQLYD----VII 335
++ + L+++ G R + V ++ + +L L PD++E+ +Q+ V+I
Sbjct: 189 HIALQVLNEMAGCRTIAVDREPGAQV-LAKELGADKVLSGGPDLIEEVRQITGGGARVVI 247
Query: 334 DCTGVGKVMEISFNYLRHGGKYVLFG 257
D G + + + L++GG ++ G
Sbjct: 248 DFVGELGIENLCWKLLKNGGDLIMVG 273
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 867,495,277
Number of Sequences: 1657284
Number of extensions: 19049262
Number of successful extensions: 61234
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 57994
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 60798
length of database: 575,637,011
effective HSP length: 100
effective length of database: 409,908,611
effective search space used: 74193458591
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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