Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P09_pT_E12
(914 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
CR541695-1|CAG46496.1| 414|Homo sapiens IDH1 protein. 415 e-115
CR536499-1|CAG38738.1| 414|Homo sapiens IDH1 protein. 415 e-115
BC012846-1|AAH12846.1| 414|Homo sapiens IDH1 protein protein. 415 e-115
AF113917-1|AAD29284.1| 414|Homo sapiens NADP+-dependent isocitr... 415 e-115
AC016697-3|AAX93221.1| 414|Homo sapiens unknown protein. 415 e-115
BC093020-1|AAH93020.1| 414|Homo sapiens isocitrate dehydrogenas... 413 e-115
BX537411-1|CAD97653.1| 414|Homo sapiens hypothetical protein pr... 413 e-115
CR533522-1|CAG38553.1| 414|Homo sapiens IDH1 protein. 412 e-114
AF020038-1|AAD02918.1| 414|Homo sapiens NADP-dependent isocitra... 406 e-113
DQ403082-1|ABD77215.1| 371|Homo sapiens isocitrate dehydrogenas... 400 e-111
X69433-1|CAA49208.1| 452|Homo sapiens isocitrate dehydrogenase... 368 e-101
U52144-1|AAC50455.1| 419|Homo sapiens isocitrate dehydrogenase ... 367 e-101
BC071828-1|AAH71828.1| 452|Homo sapiens isocitrate dehydrogenas... 367 e-101
BC009244-1|AAH09244.1| 452|Homo sapiens isocitrate dehydrogenas... 367 e-101
AK222916-1|BAD96636.1| 452|Homo sapiens isocitrate dehydrogenas... 365 e-101
U62389-1|AAB17375.1| 154|Homo sapiens putative cytosolic NADP-d... 139 1e-32
AF197566-1|AAG43470.1| 127|Homo sapiens NADP+-specific isocitra... 128 4e-29
>CR541695-1|CAG46496.1| 414|Homo sapiens IDH1 protein.
Length = 414
Score = 415 bits (1021), Expect = e-115
Identities = 192/256 (75%), Positives = 218/256 (85%), Gaps = 2/256 (0%)
Frame = -1
Query: 914 FKPXSG-EAIKHVVHEYK-GAGVALAMFNTDASIIDFAHSSFKFALDRKYPLYLSTKNTI 741
+ P G + + ++VH ++ G GVA+ M+N D SI DFAHSSF+ AL + +PLYLSTKNTI
Sbjct: 156 YTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTI 215
Query: 740 LKKYDGRFKDIFQDIYDREYKKQFEDAGIWYEHRLIDDMVAYAMKSEGGFVWACKNYDGD 561
LKKYDGRFKDIFQ+IYD++YK QFE IWYEHRLIDDMVA AMKSEGGF+WACKNYDGD
Sbjct: 216 LKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGD 275
Query: 560 VQSDSVAQGYGSLGLMTSVLICPDGKTVEAEAAHGTVTRHFRFYQQGKETSTNPIASIFA 381
VQSDSVAQGYGSLG+MTSVL+CPDGKTVEAEAAHGTVTRH+R YQ+G+ETSTNPIASIFA
Sbjct: 276 VQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFA 335
Query: 380 WTRGLLHRAKLDNNDALKNFAETLEKVCIETIESGIMTKDLAICIKGMNNVKRSDYYETF 201
WTRGL HRAKLDNN L FA LE+V IETIE+G MTKDLA CIKG+ NV+RSDY TF
Sbjct: 336 WTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTF 395
Query: 200 EFMDKLAENLKVALGQ 153
EFMDKL ENLK+ L Q
Sbjct: 396 EFMDKLGENLKIKLAQ 411
>CR536499-1|CAG38738.1| 414|Homo sapiens IDH1 protein.
Length = 414
Score = 415 bits (1021), Expect = e-115
Identities = 192/256 (75%), Positives = 218/256 (85%), Gaps = 2/256 (0%)
Frame = -1
Query: 914 FKPXSG-EAIKHVVHEYK-GAGVALAMFNTDASIIDFAHSSFKFALDRKYPLYLSTKNTI 741
+ P G + + ++VH ++ G GVA+ M+N D SI DFAHSSF+ AL + +PLYLSTKNTI
Sbjct: 156 YTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTI 215
Query: 740 LKKYDGRFKDIFQDIYDREYKKQFEDAGIWYEHRLIDDMVAYAMKSEGGFVWACKNYDGD 561
LKKYDGRFKDIFQ+IYD++YK QFE IWYEHRLIDDMVA AMKSEGGF+WACKNYDGD
Sbjct: 216 LKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGD 275
Query: 560 VQSDSVAQGYGSLGLMTSVLICPDGKTVEAEAAHGTVTRHFRFYQQGKETSTNPIASIFA 381
VQSDSVAQGYGSLG+MTSVL+CPDGKTVEAEAAHGTVTRH+R YQ+G+ETSTNPIASIFA
Sbjct: 276 VQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFA 335
Query: 380 WTRGLLHRAKLDNNDALKNFAETLEKVCIETIESGIMTKDLAICIKGMNNVKRSDYYETF 201
WTRGL HRAKLDNN L FA LE+V IETIE+G MTKDLA CIKG+ NV+RSDY TF
Sbjct: 336 WTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTF 395
Query: 200 EFMDKLAENLKVALGQ 153
EFMDKL ENLK+ L Q
Sbjct: 396 EFMDKLGENLKIKLAQ 411
>BC012846-1|AAH12846.1| 414|Homo sapiens IDH1 protein protein.
Length = 414
Score = 415 bits (1021), Expect = e-115
Identities = 192/256 (75%), Positives = 218/256 (85%), Gaps = 2/256 (0%)
Frame = -1
Query: 914 FKPXSG-EAIKHVVHEYK-GAGVALAMFNTDASIIDFAHSSFKFALDRKYPLYLSTKNTI 741
+ P G + + ++VH ++ G GVA+ M+N D SI DFAHSSF+ AL + +PLYLSTKNTI
Sbjct: 156 YTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTI 215
Query: 740 LKKYDGRFKDIFQDIYDREYKKQFEDAGIWYEHRLIDDMVAYAMKSEGGFVWACKNYDGD 561
LKKYDGRFKDIFQ+IYD++YK QFE IWYEHRLIDDMVA AMKSEGGF+WACKNYDGD
Sbjct: 216 LKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGD 275
Query: 560 VQSDSVAQGYGSLGLMTSVLICPDGKTVEAEAAHGTVTRHFRFYQQGKETSTNPIASIFA 381
VQSDSVAQGYGSLG+MTSVL+CPDGKTVEAEAAHGTVTRH+R YQ+G+ETSTNPIASIFA
Sbjct: 276 VQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFA 335
Query: 380 WTRGLLHRAKLDNNDALKNFAETLEKVCIETIESGIMTKDLAICIKGMNNVKRSDYYETF 201
WTRGL HRAKLDNN L FA LE+V IETIE+G MTKDLA CIKG+ NV+RSDY TF
Sbjct: 336 WTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTF 395
Query: 200 EFMDKLAENLKVALGQ 153
EFMDKL ENLK+ L Q
Sbjct: 396 EFMDKLGENLKIKLAQ 411
>AF113917-1|AAD29284.1| 414|Homo sapiens NADP+-dependent isocitrate
dehydrogenase protein.
Length = 414
Score = 415 bits (1021), Expect = e-115
Identities = 192/256 (75%), Positives = 218/256 (85%), Gaps = 2/256 (0%)
Frame = -1
Query: 914 FKPXSG-EAIKHVVHEYK-GAGVALAMFNTDASIIDFAHSSFKFALDRKYPLYLSTKNTI 741
+ P G + + ++VH ++ G GVA+ M+N D SI DFAHSSF+ AL + +PLYLSTKNTI
Sbjct: 156 YTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTI 215
Query: 740 LKKYDGRFKDIFQDIYDREYKKQFEDAGIWYEHRLIDDMVAYAMKSEGGFVWACKNYDGD 561
LKKYDGRFKDIFQ+IYD++YK QFE IWYEHRLIDDMVA AMKSEGGF+WACKNYDGD
Sbjct: 216 LKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGD 275
Query: 560 VQSDSVAQGYGSLGLMTSVLICPDGKTVEAEAAHGTVTRHFRFYQQGKETSTNPIASIFA 381
VQSDSVAQGYGSLG+MTSVL+CPDGKTVEAEAAHGTVTRH+R YQ+G+ETSTNPIASIFA
Sbjct: 276 VQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFA 335
Query: 380 WTRGLLHRAKLDNNDALKNFAETLEKVCIETIESGIMTKDLAICIKGMNNVKRSDYYETF 201
WTRGL HRAKLDNN L FA LE+V IETIE+G MTKDLA CIKG+ NV+RSDY TF
Sbjct: 336 WTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTF 395
Query: 200 EFMDKLAENLKVALGQ 153
EFMDKL ENLK+ L Q
Sbjct: 396 EFMDKLGENLKIKLAQ 411
>AC016697-3|AAX93221.1| 414|Homo sapiens unknown protein.
Length = 414
Score = 415 bits (1021), Expect = e-115
Identities = 192/256 (75%), Positives = 218/256 (85%), Gaps = 2/256 (0%)
Frame = -1
Query: 914 FKPXSG-EAIKHVVHEYK-GAGVALAMFNTDASIIDFAHSSFKFALDRKYPLYLSTKNTI 741
+ P G + + ++VH ++ G GVA+ M+N D SI DFAHSSF+ AL + +PLYLSTKNTI
Sbjct: 156 YTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTI 215
Query: 740 LKKYDGRFKDIFQDIYDREYKKQFEDAGIWYEHRLIDDMVAYAMKSEGGFVWACKNYDGD 561
LKKYDGRFKDIFQ+IYD++YK QFE IWYEHRLIDDMVA AMKSEGGF+WACKNYDGD
Sbjct: 216 LKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGD 275
Query: 560 VQSDSVAQGYGSLGLMTSVLICPDGKTVEAEAAHGTVTRHFRFYQQGKETSTNPIASIFA 381
VQSDSVAQGYGSLG+MTSVL+CPDGKTVEAEAAHGTVTRH+R YQ+G+ETSTNPIASIFA
Sbjct: 276 VQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFA 335
Query: 380 WTRGLLHRAKLDNNDALKNFAETLEKVCIETIESGIMTKDLAICIKGMNNVKRSDYYETF 201
WTRGL HRAKLDNN L FA LE+V IETIE+G MTKDLA CIKG+ NV+RSDY TF
Sbjct: 336 WTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTF 395
Query: 200 EFMDKLAENLKVALGQ 153
EFMDKL ENLK+ L Q
Sbjct: 396 EFMDKLGENLKIKLAQ 411
>BC093020-1|AAH93020.1| 414|Homo sapiens isocitrate dehydrogenase 1
(NADP+), soluble protein.
Length = 414
Score = 413 bits (1018), Expect = e-115
Identities = 191/256 (74%), Positives = 218/256 (85%), Gaps = 2/256 (0%)
Frame = -1
Query: 914 FKPXSG-EAIKHVVHEYK-GAGVALAMFNTDASIIDFAHSSFKFALDRKYPLYLSTKNTI 741
+ P G + + ++VH ++ G GVA+ M+N D SI DFAHSSF+ AL + +PLYLSTKNTI
Sbjct: 156 YTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTI 215
Query: 740 LKKYDGRFKDIFQDIYDREYKKQFEDAGIWYEHRLIDDMVAYAMKSEGGFVWACKNYDGD 561
LKKYDGRFKDIFQ+IYD++YK QFE IWYEHRLIDDMVA AMKSEGGF+WACKNYDGD
Sbjct: 216 LKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGD 275
Query: 560 VQSDSVAQGYGSLGLMTSVLICPDGKTVEAEAAHGTVTRHFRFYQQGKETSTNPIASIFA 381
VQSDSVAQGYGSLG+MTSVL+CPDGKTVEAE+AHGTVTRH+R YQ+G+ETSTNPIASIFA
Sbjct: 276 VQSDSVAQGYGSLGMMTSVLVCPDGKTVEAESAHGTVTRHYRMYQKGQETSTNPIASIFA 335
Query: 380 WTRGLLHRAKLDNNDALKNFAETLEKVCIETIESGIMTKDLAICIKGMNNVKRSDYYETF 201
WTRGL HRAKLDNN L FA LE+V IETIE+G MTKDLA CIKG+ NV+RSDY TF
Sbjct: 336 WTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTF 395
Query: 200 EFMDKLAENLKVALGQ 153
EFMDKL ENLK+ L Q
Sbjct: 396 EFMDKLGENLKIKLAQ 411
>BX537411-1|CAD97653.1| 414|Homo sapiens hypothetical protein
protein.
Length = 414
Score = 413 bits (1016), Expect = e-115
Identities = 192/256 (75%), Positives = 217/256 (84%), Gaps = 2/256 (0%)
Frame = -1
Query: 914 FKPXSG-EAIKHVVHEYKGAG-VALAMFNTDASIIDFAHSSFKFALDRKYPLYLSTKNTI 741
+ P G + + ++VH +G G VA+ M+N D SI DFAHSSF+ AL + +PLYLSTKNTI
Sbjct: 156 YTPSDGTQKVTYLVHNSEGGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTI 215
Query: 740 LKKYDGRFKDIFQDIYDREYKKQFEDAGIWYEHRLIDDMVAYAMKSEGGFVWACKNYDGD 561
LKKYDGRFKDIFQ+IYD++YK QFE IWYEHRLIDDMVA AMKSEGGF+WACKNYDGD
Sbjct: 216 LKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGD 275
Query: 560 VQSDSVAQGYGSLGLMTSVLICPDGKTVEAEAAHGTVTRHFRFYQQGKETSTNPIASIFA 381
VQSDSVAQGYGSLG+MTSVL+CPDGKTVEAEAAHGTVTRH+R YQ+G+ETSTNPIASIFA
Sbjct: 276 VQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFA 335
Query: 380 WTRGLLHRAKLDNNDALKNFAETLEKVCIETIESGIMTKDLAICIKGMNNVKRSDYYETF 201
WTRGL HRAKLDNN L FA LE+V IETIE+G MTKDLA CIKG+ NV+RSDY TF
Sbjct: 336 WTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTF 395
Query: 200 EFMDKLAENLKVALGQ 153
EFMDKL ENLK+ L Q
Sbjct: 396 EFMDKLGENLKIKLAQ 411
>CR533522-1|CAG38553.1| 414|Homo sapiens IDH1 protein.
Length = 414
Score = 412 bits (1014), Expect = e-114
Identities = 191/256 (74%), Positives = 217/256 (84%), Gaps = 2/256 (0%)
Frame = -1
Query: 914 FKPXSG-EAIKHVVHEYK-GAGVALAMFNTDASIIDFAHSSFKFALDRKYPLYLSTKNTI 741
+ P G + + ++VH ++ G GVA+ M+N D SI DFAHSSF+ AL + +PLYLSTKNTI
Sbjct: 156 YTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTI 215
Query: 740 LKKYDGRFKDIFQDIYDREYKKQFEDAGIWYEHRLIDDMVAYAMKSEGGFVWACKNYDGD 561
LKKYDGRFKDIFQ+IYD++YK QFE IWYEHRLIDDMVA AMKSEGGF+WACKNYDGD
Sbjct: 216 LKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGD 275
Query: 560 VQSDSVAQGYGSLGLMTSVLICPDGKTVEAEAAHGTVTRHFRFYQQGKETSTNPIASIFA 381
VQSDSVAQGYGSLG+MTSVL+CPDGKTVEAEAAHGTVTRH+R YQ+G+ETSTNPIASIFA
Sbjct: 276 VQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFA 335
Query: 380 WTRGLLHRAKLDNNDALKNFAETLEKVCIETIESGIMTKDLAICIKGMNNVKRSDYYETF 201
WTRGL HRAKLDNN L FA LE+V IETIE+G MTK LA CIKG+ NV+RSDY TF
Sbjct: 336 WTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKGLAACIKGLPNVQRSDYLNTF 395
Query: 200 EFMDKLAENLKVALGQ 153
EFMDKL ENLK+ L Q
Sbjct: 396 EFMDKLGENLKIKLAQ 411
>AF020038-1|AAD02918.1| 414|Homo sapiens NADP-dependent isocitrate
dehydrogenase protein.
Length = 414
Score = 406 bits (1000), Expect = e-113
Identities = 189/256 (73%), Positives = 216/256 (84%), Gaps = 2/256 (0%)
Frame = -1
Query: 914 FKPXSG-EAIKHVVHEYK-GAGVALAMFNTDASIIDFAHSSFKFALDRKYPLYLSTKNTI 741
+ P G + + ++VH ++ G GVA+ M+N D SI DFAHSSF+ AL + +PLYLSTKNTI
Sbjct: 156 YTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTI 215
Query: 740 LKKYDGRFKDIFQDIYDREYKKQFEDAGIWYEHRLIDDMVAYAMKSEGGFVWACKNYDGD 561
LK YDGRFKDIFQ+IYD++YK QFE IWYEHRLIDDMVA AMKSEGGF+WACKNYDGD
Sbjct: 216 LKIYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGD 275
Query: 560 VQSDSVAQGYGSLGLMTSVLICPDGKTVEAEAAHGTVTRHFRFYQQGKETSTNPIASIFA 381
VQSDSVAQGYGSLG+MTSVL+CPDGKTVEAEAAHGTVTRH+R YQ+G+ETSTN IASIFA
Sbjct: 276 VQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNLIASIFA 335
Query: 380 WTRGLLHRAKLDNNDALKNFAETLEKVCIETIESGIMTKDLAICIKGMNNVKRSDYYETF 201
WTRGL HRAKLDNN L FA LE+V IETIE+G MTKDLA CI+G+ NV+RSDY TF
Sbjct: 336 WTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLAACIRGLPNVQRSDYLNTF 395
Query: 200 EFMDKLAENLKVALGQ 153
EFMDKL ENLK+ L Q
Sbjct: 396 EFMDKLGENLKIKLAQ 411
>DQ403082-1|ABD77215.1| 371|Homo sapiens isocitrate dehydrogenase 1
protein.
Length = 371
Score = 400 bits (986), Expect = e-111
Identities = 185/245 (75%), Positives = 210/245 (85%), Gaps = 2/245 (0%)
Frame = -1
Query: 914 FKPXSG-EAIKHVVHEYK-GAGVALAMFNTDASIIDFAHSSFKFALDRKYPLYLSTKNTI 741
+ P G + + ++VH ++ G GVA+ M+N D SI DFAHSSF+ AL + +PLYLSTKNTI
Sbjct: 127 YTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTI 186
Query: 740 LKKYDGRFKDIFQDIYDREYKKQFEDAGIWYEHRLIDDMVAYAMKSEGGFVWACKNYDGD 561
LKKYDGRFKDIFQ+IYD++YK QFE IWYEHRLIDDMVA AMKSEGGF+WACKNYDGD
Sbjct: 187 LKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGD 246
Query: 560 VQSDSVAQGYGSLGLMTSVLICPDGKTVEAEAAHGTVTRHFRFYQQGKETSTNPIASIFA 381
VQSDSVAQGYGSLG+MTSVL+CPDGKTVEAEAAHGTVTRH+R YQ+G+ETSTNPIASIFA
Sbjct: 247 VQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFA 306
Query: 380 WTRGLLHRAKLDNNDALKNFAETLEKVCIETIESGIMTKDLAICIKGMNNVKRSDYYETF 201
WTRGL HRAKLDNN L FA LE+V IETIE+G MTKDLA CIKG+ NV+RSDY TF
Sbjct: 307 WTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTF 366
Query: 200 EFMDK 186
EFMDK
Sbjct: 367 EFMDK 371
>X69433-1|CAA49208.1| 452|Homo sapiens isocitrate dehydrogenase
(NADP+) protein.
Length = 452
Score = 368 bits (905), Expect = e-101
Identities = 167/256 (65%), Positives = 204/256 (79%), Gaps = 2/256 (0%)
Frame = -1
Query: 914 FKPXSGEAIKH-VVHEYKGAGVALAMFNTDASIIDFAHSSFKFALDRKYPLYLSTKNTIL 738
F P G +K V+ + GV + M+NTD SI FAHS F++A+ +K+PLY+STKNTIL
Sbjct: 196 FTPKDGSGVKEWEVYNFPAGGVGMGMYNTDESISGFAHSCFQYAIQKKWPLYMSTKNTIL 255
Query: 737 KKYDGRFKDIFQDIYDREYKKQFEDAGIWYEHRLIDDMVAYAMKSEGGFVWACKNYDGDV 558
K YDGRFKDIFQ+I+D+ YK F+ IWYEHRLIDDMVA +KS GGFVWACKNYDGDV
Sbjct: 256 KAYDGRFKDIFQEIFDKHYKTDFDKNKIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDV 315
Query: 557 QSDSVAQGYGSLGLMTSVLICPDGKTVEAEAAHGTVTRHFRFYQQGKETSTNPIASIFAW 378
QSD +AQG+GSLGLMTSVL+CPDGKT+EAEAAHGTVTRH+R +Q+G+ TSTNPIASIFAW
Sbjct: 316 QSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAW 375
Query: 377 TRGLLHRAKLDNNDALKNFAETLEKVCIETIESGIMTKDLAICIKGMNNVKRSDYY-ETF 201
TRGL HR KLD N L FA+ LEKVC+ET+ESG MTKDLA CI G++NVK ++++ T
Sbjct: 376 TRGLEHRGKLDGNQDLIRFAQMLEKVCVETVESGAMTKDLAGCIHGLSNVKLNEHFLNTM 435
Query: 200 EFMDKLAENLKVALGQ 153
+F+D + NL ALG+
Sbjct: 436 DFLDTIKSNLDRALGR 451
>U52144-1|AAC50455.1| 419|Homo sapiens isocitrate dehydrogenase
protein.
Length = 419
Score = 367 bits (903), Expect = e-101
Identities = 167/256 (65%), Positives = 204/256 (79%), Gaps = 2/256 (0%)
Frame = -1
Query: 914 FKPXSGEAIKH-VVHEYKGAGVALAMFNTDASIIDFAHSSFKFALDRKYPLYLSTKNTIL 738
F P G +K V+ + GV + M+NTD SI FAHS F++A+ +K+PLY+STKNTIL
Sbjct: 163 FTPKDGSGVKEWEVYNFPAGGVGMGMYNTDESISGFAHSCFQYAIQKKWPLYMSTKNTIL 222
Query: 737 KKYDGRFKDIFQDIYDREYKKQFEDAGIWYEHRLIDDMVAYAMKSEGGFVWACKNYDGDV 558
K YDGRFKDIFQ+I+D+ YK F+ IWYEHRLIDDMVA +KS GGFVWACKNYDGDV
Sbjct: 223 KAYDGRFKDIFQEIFDKHYKTDFDKNKIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDV 282
Query: 557 QSDSVAQGYGSLGLMTSVLICPDGKTVEAEAAHGTVTRHFRFYQQGKETSTNPIASIFAW 378
QSD +AQG+GSLGLMTSVL+CPDGKT+EAEAAHGTVTRH+R +Q+G+ TSTNPIASIFAW
Sbjct: 283 QSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAW 342
Query: 377 TRGLLHRAKLDNNDALKNFAETLEKVCIETIESGIMTKDLAICIKGMNNVKRSDYY-ETF 201
TRGL HR KLD N L FA+ LEKVC+ET+ESG MTKDLA CI G++NVK ++++ T
Sbjct: 343 TRGLEHRGKLDGNQDLIRFAQMLEKVCVETVESGAMTKDLAGCIHGLSNVKLNEHFLNTT 402
Query: 200 EFMDKLAENLKVALGQ 153
+F+D + NL ALG+
Sbjct: 403 DFLDTIKSNLDRALGR 418
>BC071828-1|AAH71828.1| 452|Homo sapiens isocitrate dehydrogenase 2
(NADP+), mitochondrial protein.
Length = 452
Score = 367 bits (903), Expect = e-101
Identities = 167/256 (65%), Positives = 204/256 (79%), Gaps = 2/256 (0%)
Frame = -1
Query: 914 FKPXSGEAIKH-VVHEYKGAGVALAMFNTDASIIDFAHSSFKFALDRKYPLYLSTKNTIL 738
F P G +K V+ + GV + M+NTD SI FAHS F++A+ +K+PLY+STKNTIL
Sbjct: 196 FTPKDGSGVKEWEVYNFPAGGVGMGMYNTDESISGFAHSCFQYAIQKKWPLYMSTKNTIL 255
Query: 737 KKYDGRFKDIFQDIYDREYKKQFEDAGIWYEHRLIDDMVAYAMKSEGGFVWACKNYDGDV 558
K YDGRFKDIFQ+I+D+ YK F+ IWYEHRLIDDMVA +KS GGFVWACKNYDGDV
Sbjct: 256 KAYDGRFKDIFQEIFDKHYKTDFDKNKIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDV 315
Query: 557 QSDSVAQGYGSLGLMTSVLICPDGKTVEAEAAHGTVTRHFRFYQQGKETSTNPIASIFAW 378
QSD +AQG+GSLGLMTSVL+CPDGKT+EAEAAHGTVTRH+R +Q+G+ TSTNPIASIFAW
Sbjct: 316 QSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAW 375
Query: 377 TRGLLHRAKLDNNDALKNFAETLEKVCIETIESGIMTKDLAICIKGMNNVKRSDYY-ETF 201
TRGL HR KLD N L FA+ LEKVC+ET+ESG MTKDLA CI G++NVK ++++ T
Sbjct: 376 TRGLEHRGKLDGNQDLIRFAQMLEKVCVETVESGAMTKDLAGCIHGLSNVKLNEHFLNTT 435
Query: 200 EFMDKLAENLKVALGQ 153
+F+D + NL ALG+
Sbjct: 436 DFLDTIKSNLDRALGR 451
>BC009244-1|AAH09244.1| 452|Homo sapiens isocitrate dehydrogenase 2
(NADP+), mitochondrial protein.
Length = 452
Score = 367 bits (903), Expect = e-101
Identities = 167/256 (65%), Positives = 204/256 (79%), Gaps = 2/256 (0%)
Frame = -1
Query: 914 FKPXSGEAIKH-VVHEYKGAGVALAMFNTDASIIDFAHSSFKFALDRKYPLYLSTKNTIL 738
F P G +K V+ + GV + M+NTD SI FAHS F++A+ +K+PLY+STKNTIL
Sbjct: 196 FTPKDGSGVKEWEVYNFPAGGVGMGMYNTDESISGFAHSCFQYAIQKKWPLYMSTKNTIL 255
Query: 737 KKYDGRFKDIFQDIYDREYKKQFEDAGIWYEHRLIDDMVAYAMKSEGGFVWACKNYDGDV 558
K YDGRFKDIFQ+I+D+ YK F+ IWYEHRLIDDMVA +KS GGFVWACKNYDGDV
Sbjct: 256 KAYDGRFKDIFQEIFDKHYKTDFDKNKIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDV 315
Query: 557 QSDSVAQGYGSLGLMTSVLICPDGKTVEAEAAHGTVTRHFRFYQQGKETSTNPIASIFAW 378
QSD +AQG+GSLGLMTSVL+CPDGKT+EAEAAHGTVTRH+R +Q+G+ TSTNPIASIFAW
Sbjct: 316 QSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAW 375
Query: 377 TRGLLHRAKLDNNDALKNFAETLEKVCIETIESGIMTKDLAICIKGMNNVKRSDYY-ETF 201
TRGL HR KLD N L FA+ LEKVC+ET+ESG MTKDLA CI G++NVK ++++ T
Sbjct: 376 TRGLEHRGKLDGNQDLIRFAQMLEKVCVETVESGAMTKDLAGCIHGLSNVKLNEHFLNTT 435
Query: 200 EFMDKLAENLKVALGQ 153
+F+D + NL ALG+
Sbjct: 436 DFLDTIKSNLDRALGR 451
>AK222916-1|BAD96636.1| 452|Homo sapiens isocitrate dehydrogenase 2
(NADP+), mitochondrial precursor variant protein.
Length = 452
Score = 365 bits (899), Expect = e-101
Identities = 166/256 (64%), Positives = 204/256 (79%), Gaps = 2/256 (0%)
Frame = -1
Query: 914 FKPXSGEAIKH-VVHEYKGAGVALAMFNTDASIIDFAHSSFKFALDRKYPLYLSTKNTIL 738
F P G +K V+ + GV + M+NTD SI FAHS F++A+ +K+PLY+STKNTIL
Sbjct: 196 FTPKDGSGVKEWEVYNFPAGGVGMGMYNTDESISGFAHSCFQYAIQKKWPLYMSTKNTIL 255
Query: 737 KKYDGRFKDIFQDIYDREYKKQFEDAGIWYEHRLIDDMVAYAMKSEGGFVWACKNYDGDV 558
K YDGRFKDIFQ+I+D+ Y+ F+ IWYEHRLIDDMVA +KS GGFVWACKNYDGDV
Sbjct: 256 KAYDGRFKDIFQEIFDKHYETDFDKNKIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDV 315
Query: 557 QSDSVAQGYGSLGLMTSVLICPDGKTVEAEAAHGTVTRHFRFYQQGKETSTNPIASIFAW 378
QSD +AQG+GSLGLMTSVL+CPDGKT+EAEAAHGTVTRH+R +Q+G+ TSTNPIASIFAW
Sbjct: 316 QSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAW 375
Query: 377 TRGLLHRAKLDNNDALKNFAETLEKVCIETIESGIMTKDLAICIKGMNNVKRSDYY-ETF 201
TRGL HR KLD N L FA+ LEKVC+ET+ESG MTKDLA CI G++NVK ++++ T
Sbjct: 376 TRGLEHRGKLDGNQDLIRFAQMLEKVCVETVESGAMTKDLAGCIHGLSNVKLNEHFLNTT 435
Query: 200 EFMDKLAENLKVALGQ 153
+F+D + NL ALG+
Sbjct: 436 DFLDTIKSNLDRALGR 451
>U62389-1|AAB17375.1| 154|Homo sapiens putative cytosolic
NADP-dependent isocitrate dehydrogenase protein.
Length = 154
Score = 139 bits (336), Expect = 1e-32
Identities = 63/98 (64%), Positives = 78/98 (79%), Gaps = 2/98 (2%)
Frame = -1
Query: 914 FKPXSG-EAIKHVVHEYK-GAGVALAMFNTDASIIDFAHSSFKFALDRKYPLYLSTKNTI 741
+ P G + + ++VH ++ G GVA+ M+N D SI DFAHSSF+ AL + +PLYLSTKNTI
Sbjct: 57 YTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTI 116
Query: 740 LKKYDGRFKDIFQDIYDREYKKQFEDAGIWYEHRLIDD 627
LKKYDGRFKDIFQ+IYD++YK QFE IWYEHRLIDD
Sbjct: 117 LKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDD 154
>AF197566-1|AAG43470.1| 127|Homo sapiens NADP+-specific isocitrate
dehydrogenase protein.
Length = 127
Score = 128 bits (308), Expect = 4e-29
Identities = 61/89 (68%), Positives = 69/89 (77%)
Frame = -1
Query: 419 KETSTNPIASIFAWTRGLLHRAKLDNNDALKNFAETLEKVCIETIESGIMTKDLAICIKG 240
+E STNPIASIFAWTRGL RAK DNN L FA LE+VCIETIE+G MTKDLA CIKG
Sbjct: 1 QEISTNPIASIFAWTRGLALRAKTDNNKELAFFANALEEVCIETIEAGFMTKDLAACIKG 60
Query: 239 MNNVKRSDYYETFEFMDKLAENLKVALGQ 153
+ + + SDY TFEFM+KL ENLK+ L Q
Sbjct: 61 LPSAQCSDYLNTFEFMEKLGENLKIKLAQ 89
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 122,183,682
Number of Sequences: 237096
Number of extensions: 2474122
Number of successful extensions: 4370
Number of sequences better than 10.0: 17
Number of HSP's better than 10.0 without gapping: 4144
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4363
length of database: 76,859,062
effective HSP length: 90
effective length of database: 55,520,422
effective search space used: 11881370308
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
- SilkBase 1999-2023 -