Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P09_pT_B13
(786 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_O15118 Cluster: Niemann-Pick C1 protein precursor; n=39... 179 6e-44
UniRef50_A7S0G1 Cluster: Predicted protein; n=1; Nematostella ve... 178 1e-43
UniRef50_Q4RWY5 Cluster: Chromosome 15 SCAF14981, whole genome s... 175 1e-42
UniRef50_UPI00015B5F3E Cluster: PREDICTED: similar to CG5722-PA;... 171 1e-41
UniRef50_UPI0000DB7411 Cluster: PREDICTED: similar to Niemann-Pi... 169 9e-41
UniRef50_UPI0000586B35 Cluster: PREDICTED: similar to Niemann-Pi... 166 5e-40
UniRef50_UPI0000D573E9 Cluster: PREDICTED: similar to CG5722-PA;... 166 6e-40
UniRef50_Q5C0X8 Cluster: SJCHGC06092 protein; n=1; Schistosoma j... 152 1e-35
UniRef50_Q9VRC9 Cluster: CG12092-PA; n=4; Diptera|Rep: CG12092-P... 146 4e-34
UniRef50_UPI0000E48D84 Cluster: PREDICTED: similar to Niemann-Pi... 146 5e-34
UniRef50_Q9UHC9 Cluster: Niemann-Pick C1-like protein 1 precurso... 136 6e-31
UniRef50_Q4H344 Cluster: Niemann-Pick disease, type C1; n=1; Cio... 132 1e-29
UniRef50_UPI000069E05B Cluster: Niemann-Pick C1-like protein 1 p... 131 2e-29
UniRef50_A7QPC0 Cluster: Chromosome chr18 scaffold_137, whole ge... 129 7e-29
UniRef50_Q4T749 Cluster: Chromosome undetermined SCAF8317, whole... 128 1e-28
UniRef50_UPI000065FF0C Cluster: Niemann-Pick C1-like protein 1 p... 128 2e-28
UniRef50_Q9SVF0 Cluster: Putative uncharacterized protein F22I13... 126 5e-28
UniRef50_Q55BN1 Cluster: NPC1 protein; n=2; Dictyostelium discoi... 124 3e-27
UniRef50_Q5KGS9 Cluster: Vacuolar membrane protein, putative; n=... 124 3e-27
UniRef50_A5BXT3 Cluster: Putative uncharacterized protein; n=1; ... 118 2e-25
UniRef50_Q12200 Cluster: Niemann-pick type C-related protein 1 p... 118 2e-25
UniRef50_Q6CBA1 Cluster: Similar to tr|Q12200 Saccharomyces cere... 113 4e-24
UniRef50_A2QWF9 Cluster: Remark: Niemann-Pick C precursor; n=16;... 112 8e-24
UniRef50_Q23E28 Cluster: Patched family protein; n=1; Tetrahymen... 109 6e-23
UniRef50_A3GGU6 Cluster: Predicted protein; n=5; Saccharomycetal... 109 8e-23
UniRef50_Q01KH5 Cluster: H0409D10.4 protein; n=5; Eukaryota|Rep:... 107 2e-22
UniRef50_Q5RJ13 Cluster: Novel protein; n=9; Euteleostomi|Rep: N... 107 4e-22
UniRef50_A7SH24 Cluster: Predicted protein; n=5; Nematostella ve... 105 9e-22
UniRef50_UPI0000E7FCF0 Cluster: PREDICTED: hypothetical protein;... 103 7e-21
UniRef50_A0CEP2 Cluster: Chromosome undetermined scaffold_172, w... 93 9e-18
UniRef50_Q9SHN9 Cluster: F7F22.1; n=2; Arabidopsis thaliana|Rep:... 90 7e-17
UniRef50_Q4SP00 Cluster: Chromosome 15 SCAF14542, whole genome s... 88 2e-16
UniRef50_Q5CIB3 Cluster: F55F8.1; n=2; Cryptosporidium|Rep: F55F... 88 3e-16
UniRef50_A7RNK5 Cluster: Predicted protein; n=1; Nematostella ve... 88 3e-16
UniRef50_UPI00003650C0 Cluster: patched domain containing 3; n=1... 87 4e-16
UniRef50_Q86P36 Cluster: RE45036p; n=7; Endopterygota|Rep: RE450... 87 6e-16
UniRef50_Q4PE83 Cluster: Putative uncharacterized protein; n=1; ... 84 4e-15
UniRef50_A0A5F1 Cluster: Patched family protein,; n=1; Toxoplasm... 83 6e-15
UniRef50_UPI00015B5B0C Cluster: PREDICTED: similar to conserved ... 82 1e-14
UniRef50_A5APM6 Cluster: Putative uncharacterized protein; n=1; ... 81 2e-14
UniRef50_Q9XXR9 Cluster: Putative uncharacterized protein ptr-19... 81 3e-14
UniRef50_A5E1Z8 Cluster: Putative uncharacterized protein; n=1; ... 77 5e-13
UniRef50_Q18129 Cluster: Patched related family protein 1; n=2; ... 77 7e-13
UniRef50_Q7PXL5 Cluster: ENSANGP00000011713; n=2; Culicidae|Rep:... 76 9e-13
UniRef50_A2XWG3 Cluster: Putative uncharacterized protein; n=2; ... 75 2e-12
UniRef50_Q19945 Cluster: Putative uncharacterized protein daf-6;... 74 4e-12
UniRef50_Q19127 Cluster: Niemann-Pick C1 protein homolog 1 precu... 74 5e-12
UniRef50_P91346 Cluster: Patched related family protein 10; n=2;... 73 1e-11
UniRef50_P34389 Cluster: Niemann-Pick C1 protein homolog 2 precu... 72 1e-11
UniRef50_P91129 Cluster: Patched related family protein 2; n=2; ... 72 2e-11
UniRef50_Q007R7 Cluster: Patched protein; n=4; Eukaryota|Rep: Pa... 71 3e-11
UniRef50_UPI0000DB6CB9 Cluster: PREDICTED: similar to PaTched Re... 69 2e-10
UniRef50_Q09938 Cluster: Patched related family protein 6; n=2; ... 68 3e-10
UniRef50_Q09614 Cluster: Protein patched homolog 1; n=3; Caenorh... 65 2e-09
UniRef50_A7RK33 Cluster: Predicted protein; n=2; Nematostella ve... 65 2e-09
UniRef50_Q4H2Z6 Cluster: Patched receptor; n=1; Ciona intestinal... 63 7e-09
UniRef50_Q9Y6C5 Cluster: Protein patched homolog 2; n=14; Theria... 63 9e-09
UniRef50_Q4RVD6 Cluster: Chromosome 15 SCAF14992, whole genome s... 62 1e-08
UniRef50_UPI00005882B2 Cluster: PREDICTED: similar to conserved ... 62 2e-08
UniRef50_Q9W6T6 Cluster: Patched-2 protein; n=7; Euteleostomi|Re... 62 2e-08
UniRef50_A4SBF8 Cluster: RND family transporter: Patched (Ptc) s... 62 2e-08
UniRef50_Q13635 Cluster: Protein patched homolog 1; n=79; Verteb... 61 3e-08
UniRef50_Q6AW16 Cluster: Patched family protein 3, isoform b; n=... 60 6e-08
UniRef50_UPI00015B5B2F Cluster: PREDICTED: similar to putative h... 59 1e-07
UniRef50_Q5CVL3 Cluster: Niemann-Pick type C1 disease protein/ p... 57 4e-07
UniRef50_Q9XWL9 Cluster: Putative uncharacterized protein ptr-18... 53 7e-06
UniRef50_Q5DTE5 Cluster: Putative uncharacterized protein ptr-17... 52 2e-05
UniRef50_Q09934 Cluster: Putative uncharacterized protein ptr-13... 52 2e-05
UniRef50_Q9U1R3 Cluster: Putative uncharacterized protein ptr-22... 51 3e-05
UniRef50_Q95YD0 Cluster: Patched related family protein 4; n=2; ... 51 4e-05
UniRef50_Q010M7 Cluster: Predicted membrane protein; n=3; Eukary... 50 5e-05
UniRef50_Q4T1E7 Cluster: Chromosome 12 SCAF10644, whole genome s... 37 5e-05
UniRef50_O16307 Cluster: Patched related family protein 16; n=2;... 49 1e-04
UniRef50_UPI0000DA314A Cluster: PREDICTED: similar to Ptc-relate... 48 2e-04
UniRef50_O61894 Cluster: Patched related family protein 15; n=2;... 48 2e-04
UniRef50_O16530 Cluster: Patched related family protein 3; n=2; ... 48 2e-04
UniRef50_Q03602 Cluster: Patched-related protein 9; n=2; Caenorh... 48 2e-04
UniRef50_A7RP60 Cluster: Predicted protein; n=1; Nematostella ve... 48 3e-04
UniRef50_UPI0000E48C80 Cluster: PREDICTED: similar to Fbxw9 prot... 48 4e-04
UniRef50_Q21883 Cluster: Putative uncharacterized protein ptr-14... 44 0.003
UniRef50_O02246 Cluster: Putative uncharacterized protein ptr-23... 44 0.003
UniRef50_Q00U42 Cluster: Novel protein; n=2; Ostreococcus|Rep: N... 42 0.013
UniRef50_Q9NAB5 Cluster: Putative uncharacterized protein ptr-20... 42 0.013
UniRef50_Q09540 Cluster: Patched family protein 2; n=1; Caenorha... 42 0.018
UniRef50_A1U382 Cluster: Transport protein, putative; n=1; Marin... 41 0.040
UniRef50_O44978 Cluster: Patched related family protein 11; n=2;... 41 0.040
UniRef50_Q12II7 Cluster: Cation/multidrug efflux pump-like prote... 40 0.071
UniRef50_UPI0000E4A16C Cluster: PREDICTED: similar to dispatched... 39 0.12
UniRef50_P91184 Cluster: Patched related family protein 5; n=2; ... 39 0.12
UniRef50_Q5VTU9 Cluster: Patched domain-containing protein 2; n=... 39 0.12
UniRef50_Q54MS4 Cluster: Putative uncharacterized protein; n=2; ... 39 0.16
UniRef50_Q1N6G9 Cluster: Membrane protein, putative; n=2; Gammap... 38 0.38
UniRef50_Q5RIV7 Cluster: Patched domain-containing protein 1; n=... 37 0.50
UniRef50_UPI0000E470D2 Cluster: PREDICTED: hypothetical protein,... 37 0.66
UniRef50_Q2AGZ0 Cluster: Hydrophobe/amphiphile efflux-3 HAE3 pre... 36 0.87
UniRef50_Q8D4H9 Cluster: Cation/multidrug efflux pump; n=13; Gam... 36 1.2
UniRef50_Q5V7L9 Cluster: Putative lipid/cholesterol transport; n... 35 2.0
UniRef50_Q21L50 Cluster: Patched; n=2; Gammaproteobacteria|Rep: ... 35 2.7
UniRef50_A1ZFX3 Cluster: Membrane protein, putative; n=1; Micros... 35 2.7
UniRef50_Q9N2Z6 Cluster: Patched related family protein 21; n=2;... 35 2.7
UniRef50_UPI0000E477D4 Cluster: PREDICTED: hypothetical protein;... 34 3.5
UniRef50_Q1IYF0 Cluster: Acriflavin resistance protein; n=1; Dei... 34 3.5
UniRef50_Q0BSN4 Cluster: Cobalt-zinc-cadmium resistance protein ... 34 3.5
UniRef50_Q21FB7 Cluster: Patched; n=3; Gammaproteobacteria|Rep: ... 34 4.6
UniRef50_A7RP59 Cluster: Predicted protein; n=1; Nematostella ve... 34 4.6
UniRef50_Q0VPB5 Cluster: Transport protein, putative; n=1; Alcan... 33 6.1
UniRef50_Q0SUR3 Cluster: Antibiotic ABC transporter, permease pr... 33 6.1
UniRef50_UPI0000D8B388 Cluster: hornerin; n=2; Euteleostomi|Rep:... 33 8.1
UniRef50_Q12M39 Cluster: Acriflavin resistance protein; n=1; She... 33 8.1
UniRef50_A1HR74 Cluster: 4-diphosphocytidyl-2C-methyl-D-erythrit... 33 8.1
UniRef50_A0Z591 Cluster: Putative integral membrane protein; n=1... 33 8.1
UniRef50_A0NQP7 Cluster: Zinc uptake ABC transporter, substrate-... 33 8.1
UniRef50_Q18JY4 Cluster: Probable substrate efflux/proton antipo... 33 8.1
>UniRef50_O15118 Cluster: Niemann-Pick C1 protein precursor; n=39;
Chordata|Rep: Niemann-Pick C1 protein precursor - Homo
sapiens (Human)
Length = 1278
Score = 179 bits (436), Expect = 6e-44
Identities = 88/135 (65%), Positives = 103/135 (76%), Gaps = 2/135 (1%)
Frame = -1
Query: 744 NLGGLMYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSFSVSXXXXXXXXXADALLRMGS 565
N+ G+M+ WGISLNAVSLVNLVM+ GISVEFCSH+ +F+VS +AL MGS
Sbjct: 1137 NMFGVMWLWGISLNAVSLVNLVMSCGISVEFCSHITRAFTVSMKGSRVERAEEALAHMGS 1196
Query: 564 SVLSGITLTKFGGIIVLATAKSQIFQVFYFRMYLGIVLFGAAHGLVFLPVMLSYIGSPVN 385
SV SGITLTKFGGI+VLA AKSQIFQ+FYFRMYL +VL GA HGL+FLPV+LSYIG VN
Sbjct: 1197 SVFSGITLTKFGGIVVLAFAKSQIFQIFYFRMYLAMVLLGATHGLIFLPVLLSYIGPSVN 1256
Query: 384 KQK--LANQRRRGNE 346
K K +R +G E
Sbjct: 1257 KAKSCATEERYKGTE 1271
>UniRef50_A7S0G1 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella vectensis
Length = 1277
Score = 178 bits (434), Expect = 1e-43
Identities = 86/129 (66%), Positives = 100/129 (77%)
Frame = -1
Query: 783 ALXXXXXXXXXXVNLGGLMYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSFSVSXXXXX 604
AL NL GLMY W ISLNA+S+VNLVMAVGISVEFCSH+ +F+V+
Sbjct: 1125 ALIVTFTVAMIITNLLGLMYLWSISLNAISIVNLVMAVGISVEFCSHIARAFAVNTRNTK 1184
Query: 603 XXXXADALLRMGSSVLSGITLTKFGGIIVLATAKSQIFQVFYFRMYLGIVLFGAAHGLVF 424
+AL+ MGSSVLSGITLTKFGGIIVLA AKS+IF++FYFRMY+GIVLFGA HGLVF
Sbjct: 1185 RERAEEALIEMGSSVLSGITLTKFGGIIVLAFAKSRIFEIFYFRMYVGIVLFGALHGLVF 1244
Query: 423 LPVMLSYIG 397
LPV+LSY+G
Sbjct: 1245 LPVLLSYVG 1253
>UniRef50_Q4RWY5 Cluster: Chromosome 15 SCAF14981, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 15 SCAF14981, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 1209
Score = 175 bits (425), Expect = 1e-42
Identities = 84/116 (72%), Positives = 96/116 (82%)
Frame = -1
Query: 744 NLGGLMYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSFSVSXXXXXXXXXADALLRMGS 565
N+ G+M+ WGISLNAVSLVNLVM+ GISVEFCSH+V +FS+S +AL MGS
Sbjct: 1094 NMFGVMWLWGISLNAVSLVNLVMSCGISVEFCSHIVRAFSISMKKKKVGRAEEALAHMGS 1153
Query: 564 SVLSGITLTKFGGIIVLATAKSQIFQVFYFRMYLGIVLFGAAHGLVFLPVMLSYIG 397
SV SGITLTKFGGI++LA +KSQIFQVFYFRMYL IVL GAAHGLVFLPV+LSYIG
Sbjct: 1154 SVFSGITLTKFGGILILALSKSQIFQVFYFRMYLAIVLLGAAHGLVFLPVLLSYIG 1209
>UniRef50_UPI00015B5F3E Cluster: PREDICTED: similar to CG5722-PA; n=1;
Nasonia vitripennis|Rep: PREDICTED: similar to CG5722-PA
- Nasonia vitripennis
Length = 1253
Score = 171 bits (417), Expect = 1e-41
Identities = 90/135 (66%), Positives = 101/135 (74%)
Frame = -1
Query: 786 SALXXXXXXXXXXVNLGGLMYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSFSVSXXXX 607
SA+ V+L GLMYW GISLN VSLVNLVMA GISVEFCSH+VH++ VS
Sbjct: 1117 SAIIVLLTVFMITVDLCGLMYWVGISLNGVSLVNLVMATGISVEFCSHIVHAYLVSTKKT 1176
Query: 606 XXXXXADALLRMGSSVLSGITLTKFGGIIVLATAKSQIFQVFYFRMYLGIVLFGAAHGLV 427
A+AL R+GSSV SGITLTKF GI VL AK+QIF VFYFRMYLGIVL GAAHGL+
Sbjct: 1177 REKKAAEALSRVGSSVFSGITLTKFVGIAVLGFAKTQIFTVFYFRMYLGIVLLGAAHGLI 1236
Query: 426 FLPVMLSYIGSPVNK 382
FLPV+LS+IG PV K
Sbjct: 1237 FLPVLLSFIG-PVQK 1250
>UniRef50_UPI0000DB7411 Cluster: PREDICTED: similar to Niemann-Pick
Type C-1 CG5722-PA; n=1; Apis mellifera|Rep: PREDICTED:
similar to Niemann-Pick Type C-1 CG5722-PA - Apis
mellifera
Length = 1238
Score = 169 bits (410), Expect = 9e-41
Identities = 79/116 (68%), Positives = 94/116 (81%)
Frame = -1
Query: 744 NLGGLMYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSFSVSXXXXXXXXXADALLRMGS 565
N+GGLMYWW I LNAVSLVNLV++VGISVEFCSH++HS+ S +D L GS
Sbjct: 1122 NIGGLMYWWHIELNAVSLVNLVVSVGISVEFCSHIIHSYLKSKKETKIERASDTLNHTGS 1181
Query: 564 SVLSGITLTKFGGIIVLATAKSQIFQVFYFRMYLGIVLFGAAHGLVFLPVMLSYIG 397
SV SGITLTK GI+VLA AK+QIF+VF+FRMYL IV+FGAAHGL+FLPV+LS+IG
Sbjct: 1182 SVFSGITLTKIIGIVVLAFAKTQIFEVFFFRMYLSIVVFGAAHGLIFLPVLLSFIG 1237
>UniRef50_UPI0000586B35 Cluster: PREDICTED: similar to Niemann-Pick C
disease protein isoform 1; n=1; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to Niemann-Pick C
disease protein isoform 1 - Strongylocentrotus purpuratus
Length = 1332
Score = 166 bits (404), Expect = 5e-40
Identities = 76/126 (60%), Positives = 99/126 (78%)
Frame = -1
Query: 732 LMYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSFSVSXXXXXXXXXADALLRMGSSVLS 553
+MY WGI LNA+SLVNL+M+VGISVEFCSH+V +F++S DAL +GSSV S
Sbjct: 1182 MMYLWGIDLNAISLVNLIMSVGISVEFCSHIVKAFTLSTAMTRLERAQDALAHVGSSVFS 1241
Query: 552 GITLTKFGGIIVLATAKSQIFQVFYFRMYLGIVLFGAAHGLVFLPVMLSYIGSPVNKQKL 373
GITLTK GII+LA + SQ+F+V+YFRMYLG+V+FGA HGL+FLPV+LSYIG VNK ++
Sbjct: 1242 GITLTKAFGIIILAFSHSQLFKVYYFRMYLGMVVFGATHGLIFLPVLLSYIGPGVNKARI 1301
Query: 372 ANQRRR 355
++ +
Sbjct: 1302 LEEQEQ 1307
>UniRef50_UPI0000D573E9 Cluster: PREDICTED: similar to CG5722-PA; n=1;
Tribolium castaneum|Rep: PREDICTED: similar to CG5722-PA
- Tribolium castaneum
Length = 1210
Score = 166 bits (403), Expect = 6e-40
Identities = 80/133 (60%), Positives = 98/133 (73%)
Frame = -1
Query: 735 GLMYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSFSVSXXXXXXXXXADALLRMGSSVL 556
GLMY+W I+ NA+SLVNLVM+VGI+VEFC H+VH + S +DA MGSSVL
Sbjct: 939 GLMYFWNINFNAISLVNLVMSVGIAVEFCGHIVHHYIHSSKLSPLEKASDAFAEMGSSVL 998
Query: 555 SGITLTKFGGIIVLATAKSQIFQVFYFRMYLGIVLFGAAHGLVFLPVMLSYIGSPVNKQK 376
SGITLTKF GIIVLA A+SQIFQ+F+FRMYLGIV+ GA HGL+FLPV+LS++G V K
Sbjct: 999 SGITLTKFSGIIVLAFARSQIFQIFFFRMYLGIVIIGALHGLIFLPVLLSFLGFFVVTSK 1058
Query: 375 LANQRRRGNETTV 337
+ + G E V
Sbjct: 1059 IRGHQNCGPEHLV 1071
>UniRef50_Q5C0X8 Cluster: SJCHGC06092 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC06092 protein - Schistosoma
japonicum (Blood fluke)
Length = 182
Score = 152 bits (368), Expect = 1e-35
Identities = 71/141 (50%), Positives = 99/141 (70%)
Frame = -1
Query: 744 NLGGLMYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSFSVSXXXXXXXXXADALLRMGS 565
++ +M W I+LNA+SLVNLV+A+GISVEFC+H+V +F++S +AL MGS
Sbjct: 34 SVSAVMVLWSITLNALSLVNLVVALGISVEFCAHIVRAFTISVLPTRVERAKEALNEMGS 93
Query: 564 SVLSGITLTKFGGIIVLATAKSQIFQVFYFRMYLGIVLFGAAHGLVFLPVMLSYIGSPVN 385
S+L GITLTK GGI+VLA +KS++FQ+FYFRMYL ++LFGA GL+ LPV LSY G +N
Sbjct: 94 SILRGITLTKLGGIVVLAASKSRLFQIFYFRMYLSMILFGAFTGLIILPVYLSYFGPKLN 153
Query: 384 KQKLANQRRRGNETTVAESSL 322
++ R N ++ + L
Sbjct: 154 LAMSSSNRSNSNHSSSNNNDL 174
>UniRef50_Q9VRC9 Cluster: CG12092-PA; n=4; Diptera|Rep: CG12092-PA -
Drosophila melanogaster (Fruit fly)
Length = 1223
Score = 146 bits (355), Expect = 4e-34
Identities = 80/137 (58%), Positives = 95/137 (69%)
Frame = -1
Query: 744 NLGGLMYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSFSVSXXXXXXXXXADALLRMGS 565
N+ G+M+ W I+LNA+SLVNLV+ VGI VEF +H+V SF +L GS
Sbjct: 1087 NMLGMMWAWSINLNAISLVNLVVCVGIGVEFVAHIVRSFK-RAEGTAQERARHSLNVTGS 1145
Query: 564 SVLSGITLTKFGGIIVLATAKSQIFQVFYFRMYLGIVLFGAAHGLVFLPVMLSYIGSPVN 385
SVLSGITLTKF GI+VL + SQIFQVFYFRMYLGIVL GAAHGL+ LPV+LS +G P
Sbjct: 1146 SVLSGITLTKFAGIVVLGFSNSQIFQVFYFRMYLGIVLIGAAHGLILLPVLLSLLGPP-- 1203
Query: 384 KQKLANQRRRGNETTVA 334
QKLA R G E T +
Sbjct: 1204 -QKLA--RSSGAEPTAS 1217
>UniRef50_UPI0000E48D84 Cluster: PREDICTED: similar to Niemann-Pick
C disease protein; n=3; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to Niemann-Pick C
disease protein - Strongylocentrotus purpuratus
Length = 705
Score = 146 bits (354), Expect = 5e-34
Identities = 71/117 (60%), Positives = 84/117 (71%)
Frame = -1
Query: 735 GLMYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSFSVSXXXXXXXXXADALLRMGSSVL 556
G+MY W I NAVSLVNL+MAVG+SVEF SH+ SFS+ AL MGSSVL
Sbjct: 500 GVMYLWNIEFNAVSLVNLMMAVGMSVEFVSHITRSFSICVKEGRLERAEYALATMGSSVL 559
Query: 555 SGITLTKFGGIIVLATAKSQIFQVFYFRMYLGIVLFGAAHGLVFLPVMLSYIGSPVN 385
SG+ +T GIIVLA AKSQ+F VFYFRM+L I L G HGL+FLPV+LSYIG P++
Sbjct: 560 SGVAMTNLPGIIVLAFAKSQLFVVFYFRMFLTITLVGTVHGLIFLPVVLSYIGKPIS 616
>UniRef50_Q9UHC9 Cluster: Niemann-Pick C1-like protein 1 precursor;
n=23; Tetrapoda|Rep: Niemann-Pick C1-like protein 1
precursor - Homo sapiens (Human)
Length = 1359
Score = 136 bits (329), Expect = 6e-31
Identities = 67/134 (50%), Positives = 89/134 (66%)
Frame = -1
Query: 735 GLMYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSFSVSXXXXXXXXXADALLRMGSSVL 556
G M WGIS NAVSL+NLV AVG+SVEF SH+ SF++S +A + MGS+V
Sbjct: 1181 GFMALWGISYNAVSLINLVSAVGMSVEFVSHITRSFAISTKPTWLERAKEATISMGSAVF 1240
Query: 555 SGITLTKFGGIIVLATAKSQIFQVFYFRMYLGIVLFGAAHGLVFLPVMLSYIGSPVNKQK 376
+G+ +T GI+VL AK+Q+ Q+F+FR+ L I L G HGLVFLPV+LSY+G VN
Sbjct: 1241 AGVAMTNLPGILVLGLAKAQLIQIFFFRLNLLITLLGLLHGLVFLPVILSYVGPDVN-PA 1299
Query: 375 LANQRRRGNETTVA 334
LA +++R E A
Sbjct: 1300 LALEQKRAEEAVAA 1313
>UniRef50_Q4H344 Cluster: Niemann-Pick disease, type C1; n=1; Ciona
intestinalis|Rep: Niemann-Pick disease, type C1 - Ciona
intestinalis (Transparent sea squirt)
Length = 620
Score = 132 bits (319), Expect = 1e-29
Identities = 63/132 (47%), Positives = 85/132 (64%)
Frame = -1
Query: 735 GLMYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSFSVSXXXXXXXXXADALLRMGSSVL 556
GL WG+ +NAVSL+NLV A+G+SVEF SH+V +FS+ +++ MG +V
Sbjct: 448 GLCSLWGVDMNAVSLINLVAAIGLSVEFISHVVRTFSLKTHISKKKRVIESMTTMGPAVF 507
Query: 555 SGITLTKFGGIIVLATAKSQIFQVFYFRMYLGIVLFGAAHGLVFLPVMLSYIGSPVNKQK 376
+G+ LT GIIVL A +Q+ Q+F+FRM L I L G AHGL+FLPV LSY G PVNK
Sbjct: 508 AGVALTNLPGIIVLNWATAQLIQIFFFRMCLVITLLGTAHGLIFLPVFLSYFGPPVNKAI 567
Query: 375 LANQRRRGNETT 340
L ++ + T
Sbjct: 568 LYEEQSELRKAT 579
>UniRef50_UPI000069E05B Cluster: Niemann-Pick C1-like protein 1
precursor.; n=2; Xenopus tropicalis|Rep: Niemann-Pick
C1-like protein 1 precursor. - Xenopus tropicalis
Length = 1260
Score = 131 bits (316), Expect = 2e-29
Identities = 61/113 (53%), Positives = 79/113 (69%)
Frame = -1
Query: 735 GLMYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSFSVSXXXXXXXXXADALLRMGSSVL 556
G+M WGI NA+SL+NLV AVGISVEF SHL SF++S +A + MGS+V
Sbjct: 1148 GVMTLWGIDYNAISLINLVTAVGISVEFVSHLTRSFAISSKPNKVERAKEATINMGSAVF 1207
Query: 555 SGITLTKFGGIIVLATAKSQIFQVFYFRMYLGIVLFGAAHGLVFLPVMLSYIG 397
+G+ +T GIIVLA AK+Q+ Q+F+FR+ L I L G HGL+FLPV+LSY G
Sbjct: 1208 AGVAMTNLPGIIVLAFAKAQLIQIFFFRLNLTITLLGLVHGLIFLPVVLSYFG 1260
>UniRef50_A7QPC0 Cluster: Chromosome chr18 scaffold_137, whole genome
shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
chr18 scaffold_137, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 1263
Score = 129 bits (312), Expect = 7e-29
Identities = 66/118 (55%), Positives = 85/118 (72%)
Frame = -1
Query: 744 NLGGLMYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSFSVSXXXXXXXXXADALLRMGS 565
+L G+M I LNA+S+VNLVMAVGI+VEFC H+ H+FSVS +AL MG+
Sbjct: 1128 DLMGVMAILNIQLNALSVVNLVMAVGIAVEFCVHITHAFSVSSGDRNQRMK-EALGTMGA 1186
Query: 564 SVLSGITLTKFGGIIVLATAKSQIFQVFYFRMYLGIVLFGAAHGLVFLPVMLSYIGSP 391
SV SGITLTK G+IVL +++++F V+YF+MYL +VL G HGLVFLPV+LS G P
Sbjct: 1187 SVFSGITLTKLVGVIVLCFSRTEVFVVYYFQMYLALVLLGFLHGLVFLPVVLSMCGPP 1244
>UniRef50_Q4T749 Cluster: Chromosome undetermined SCAF8317, whole
genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome undetermined SCAF8317, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 1132
Score = 128 bits (310), Expect = 1e-28
Identities = 60/113 (53%), Positives = 80/113 (70%)
Frame = -1
Query: 735 GLMYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSFSVSXXXXXXXXXADALLRMGSSVL 556
G+M WGI NAV+L+NLV AVGISVEF SH+ SF++S +A +MGS+V
Sbjct: 1012 GVMTLWGIDYNAVALINLVTAVGISVEFVSHMTRSFALSIKPTHVERAKEATAQMGSAVF 1071
Query: 555 SGITLTKFGGIIVLATAKSQIFQVFYFRMYLGIVLFGAAHGLVFLPVMLSYIG 397
+G+ +T GI+VLA AK+Q+ Q+F+FR+ L I L G AHGL+FLPV+LSY G
Sbjct: 1072 AGVAMTNLPGILVLAFAKAQLIQIFFFRLNLVITLLGMAHGLIFLPVLLSYFG 1124
>UniRef50_UPI000065FF0C Cluster: Niemann-Pick C1-like protein 1
precursor.; n=1; Takifugu rubripes|Rep: Niemann-Pick
C1-like protein 1 precursor. - Takifugu rubripes
Length = 1293
Score = 128 bits (308), Expect = 2e-28
Identities = 60/113 (53%), Positives = 79/113 (69%)
Frame = -1
Query: 735 GLMYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSFSVSXXXXXXXXXADALLRMGSSVL 556
G+M WGI NAV+L+NLV AVGISVEF SH+ SF++S +A +MGS+V
Sbjct: 1181 GVMTLWGIDYNAVALINLVTAVGISVEFVSHMTRSFALSVQPSHVERAKEATAKMGSAVF 1240
Query: 555 SGITLTKFGGIIVLATAKSQIFQVFYFRMYLGIVLFGAAHGLVFLPVMLSYIG 397
+G+ +T GI+VLA AK+Q+ Q+F+FR+ L I L G HGLVFLPV+LSY G
Sbjct: 1241 AGVAMTNLPGILVLAFAKAQLIQIFFFRLNLVITLLGLVHGLVFLPVLLSYFG 1293
>UniRef50_Q9SVF0 Cluster: Putative uncharacterized protein F22I13.120;
n=2; Arabidopsis thaliana|Rep: Putative uncharacterized
protein F22I13.120 - Arabidopsis thaliana (Mouse-ear
cress)
Length = 1055
Score = 126 bits (305), Expect = 5e-28
Identities = 62/109 (56%), Positives = 80/109 (73%)
Frame = -1
Query: 717 GISLNAVSLVNLVMAVGISVEFCSHLVHSFSVSXXXXXXXXXADALLRMGSSVLSGITLT 538
GI LNAVS+VNL+M++GI+VEFC H+ H+F +S +AL MG+SV SGITLT
Sbjct: 928 GIQLNAVSVVNLIMSIGIAVEFCVHISHAFLMSSGDREHRAR-EALETMGASVFSGITLT 986
Query: 537 KFGGIIVLATAKSQIFQVFYFRMYLGIVLFGAAHGLVFLPVMLSYIGSP 391
K G+IVL A+S+IF V+YF+MYL +V+ G HGLVFLPV+LS G P
Sbjct: 987 KLVGVIVLCFARSEIFVVYYFQMYLALVIIGFLHGLVFLPVILSLAGPP 1035
>UniRef50_Q55BN1 Cluster: NPC1 protein; n=2; Dictyostelium
discoideum|Rep: NPC1 protein - Dictyostelium discoideum
AX4
Length = 1342
Score = 124 bits (298), Expect = 3e-27
Identities = 60/118 (50%), Positives = 80/118 (67%), Gaps = 1/118 (0%)
Frame = -1
Query: 744 NLGGLMYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSF-SVSXXXXXXXXXADALLRMG 568
+L G+M W ISLNAVS+VN+VMA+GI +EFC H+ +F + A+ MG
Sbjct: 1204 DLLGIMALWNISLNAVSVVNVVMAIGIGIEFCVHIASTFINAPKHFSRDQKAKYAVTEMG 1263
Query: 567 SSVLSGITLTKFGGIIVLATAKSQIFQVFYFRMYLGIVLFGAAHGLVFLPVMLSYIGS 394
SS++SGI +TK G++VL + S+IF V+YFRMYL IV G HGLVFLPV+LS G+
Sbjct: 1264 SSIISGIFITKLLGVVVLGFSTSEIFTVYYFRMYLSIVFLGGLHGLVFLPVLLSLFGT 1321
>UniRef50_Q5KGS9 Cluster: Vacuolar membrane protein, putative; n=2;
Filobasidiella neoformans|Rep: Vacuolar membrane protein,
putative - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 1330
Score = 124 bits (298), Expect = 3e-27
Identities = 63/126 (50%), Positives = 86/126 (68%), Gaps = 10/126 (7%)
Frame = -1
Query: 744 NLGGLMYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSF----------SVSXXXXXXXX 595
N+ G+M +WGISLNA+SLVNLV+++GI+VEFCSH+ +F V
Sbjct: 1168 NVMGVMGYWGISLNAISLVNLVISLGIAVEFCSHIARAFMGAGSGLPLDKVEGRKERDER 1227
Query: 594 XADALLRMGSSVLSGITLTKFGGIIVLATAKSQIFQVFYFRMYLGIVLFGAAHGLVFLPV 415
AL+ +G SV SGIT+TK GI VLA +S++ +V+YFRM+L ++L GA HGLV LPV
Sbjct: 1228 AWTALVDVGPSVFSGITMTKLIGISVLALTRSKLLEVYYFRMWLSLILSGALHGLVLLPV 1287
Query: 414 MLSYIG 397
+LSY+G
Sbjct: 1288 LLSYLG 1293
>UniRef50_A5BXT3 Cluster: Putative uncharacterized protein; n=1;
Vitis vinifera|Rep: Putative uncharacterized protein -
Vitis vinifera (Grape)
Length = 692
Score = 118 bits (284), Expect = 2e-25
Identities = 67/126 (53%), Positives = 83/126 (65%), Gaps = 11/126 (8%)
Frame = -1
Query: 735 GLMYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSFSVSXXXXXXXXXADALLRMGSSVL 556
G+M I LNAVS+VNL+M++GI+VEFC H+ H+FSVS AL MG+SV
Sbjct: 548 GVMACLDIQLNAVSVVNLIMSIGIAVEFCVHISHAFSVSQGDRNQRAKL-ALGTMGASVF 606
Query: 555 -----------SGITLTKFGGIIVLATAKSQIFQVFYFRMYLGIVLFGAAHGLVFLPVML 409
SGITLTK G+IVL +KS+IF V+YF+MYL +VL G HGLVFLPV+L
Sbjct: 607 RCLYFDFDFFFSGITLTKLVGVIVLCFSKSEIFVVYYFQMYLALVLIGFLHGLVFLPVIL 666
Query: 408 SYIGSP 391
S IG P
Sbjct: 667 SMIGPP 672
>UniRef50_Q12200 Cluster: Niemann-pick type C-related protein 1
precursor; n=7; Saccharomycetales|Rep: Niemann-pick type
C-related protein 1 precursor - Saccharomyces cerevisiae
(Baker's yeast)
Length = 1170
Score = 118 bits (283), Expect = 2e-25
Identities = 60/119 (50%), Positives = 79/119 (66%), Gaps = 3/119 (2%)
Frame = -1
Query: 744 NLGGLMYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSFSVSXXXXXXXXXADALLRM-- 571
++G LM GISLNAVSLVNL++ VG+ VEFC H+V SF+V + L +
Sbjct: 1039 DIGALMALLGISLNAVSLVNLIICVGLGVEFCVHIVRSFTVVPSETKKDANSRVLYSLNT 1098
Query: 570 -GSSVLSGITLTKFGGIIVLATAKSQIFQVFYFRMYLGIVLFGAAHGLVFLPVMLSYIG 397
G SV+ GITLTKF G+ VLA A+S+IF VFYFRM+ +++ A H L+FLP +LS G
Sbjct: 1099 IGESVIKGITLTKFIGVCVLAFAQSKIFDVFYFRMWFTLIIVAALHALLFLPALLSLFG 1157
>UniRef50_Q6CBA1 Cluster: Similar to tr|Q12200 Saccharomyces
cerevisiae YPL006W NCR1; n=1; Yarrowia lipolytica|Rep:
Similar to tr|Q12200 Saccharomyces cerevisiae YPL006W
NCR1 - Yarrowia lipolytica (Candida lipolytica)
Length = 1239
Score = 113 bits (273), Expect = 4e-24
Identities = 54/124 (43%), Positives = 79/124 (63%), Gaps = 8/124 (6%)
Frame = -1
Query: 744 NLGGLMYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSFS--------VSXXXXXXXXXA 589
N+ G M W ++LNA+SLVNLV+ VG+ VEFC HL +F+ +
Sbjct: 1083 NIVGFMAIWNVNLNAISLVNLVICVGLGVEFCVHLARAFTTVSANSSHIRMSPTKNTRTF 1142
Query: 588 DALLRMGSSVLSGITLTKFGGIIVLATAKSQIFQVFYFRMYLGIVLFGAAHGLVFLPVML 409
+AL+ +G SV GI +TKF G+ VLA +S+IF+V+YFR++L +V+ H L+ LPV+L
Sbjct: 1143 EALVGVGGSVFGGIAMTKFLGVFVLAFTRSKIFEVYYFRVWLALVIVATTHSLILLPVLL 1202
Query: 408 SYIG 397
+YIG
Sbjct: 1203 TYIG 1206
>UniRef50_A2QWF9 Cluster: Remark: Niemann-Pick C precursor; n=16;
Pezizomycotina|Rep: Remark: Niemann-Pick C precursor -
Aspergillus niger
Length = 1277
Score = 112 bits (270), Expect = 8e-24
Identities = 58/123 (47%), Positives = 81/123 (65%), Gaps = 10/123 (8%)
Frame = -1
Query: 735 GLMYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSF-----SVSXXXXXXXXXAD----- 586
G M G+SLNAVSLVNL++ VGI+VEFC+H+ +F ++ D
Sbjct: 1119 GAMAIAGVSLNAVSLVNLIICVGIAVEFCAHIARAFMFPSRAIMEKVPTKFRGKDARAWT 1178
Query: 585 ALLRMGSSVLSGITLTKFGGIIVLATAKSQIFQVFYFRMYLGIVLFGAAHGLVFLPVMLS 406
AL+ +G SV SGIT+TK G+ VLA +S+IF+++YFR++L ++LF A H L+FLPV LS
Sbjct: 1179 ALVNVGGSVFSGITVTKLLGVCVLAFTRSKIFEIYYFRVWLALILFAATHALIFLPVALS 1238
Query: 405 YIG 397
Y G
Sbjct: 1239 YFG 1241
>UniRef50_Q23E28 Cluster: Patched family protein; n=1; Tetrahymena
thermophila SB210|Rep: Patched family protein -
Tetrahymena thermophila SB210
Length = 1207
Score = 109 bits (263), Expect = 6e-23
Identities = 58/142 (40%), Positives = 90/142 (63%)
Frame = -1
Query: 714 ISLNAVSLVNLVMAVGISVEFCSHLVHSFSVSXXXXXXXXXADALLRMGSSVLSGITLTK 535
I +NAVS+VNL+ +VG+ VEFC HLV S+ ++ +A+ +MGS++L GI TK
Sbjct: 1049 IEINAVSVVNLITSVGLGVEFCVHLVISY-MNTPGNREQKVINAVKQMGSNILVGIASTK 1107
Query: 534 FGGIIVLATAKSQIFQVFYFRMYLGIVLFGAAHGLVFLPVMLSYIGSPVNKQKLANQRRR 355
F G+IVL A S++F+++YFRMY+ I+ G GL+FLP +L YIG PV K + +
Sbjct: 1108 FIGVIVLGFASSEMFRIYYFRMYMAIIFLGVFQGLMFLPTVLYYIG-PVTKGRTSESFI- 1165
Query: 354 GNETTVAESSLTRVHL*NVTEI 289
+++ ++E S + TE+
Sbjct: 1166 -HKSDISEGSQEEEEVFETTEV 1186
>UniRef50_A3GGU6 Cluster: Predicted protein; n=5;
Saccharomycetales|Rep: Predicted protein - Pichia
stipitis (Yeast)
Length = 1268
Score = 109 bits (262), Expect = 8e-23
Identities = 53/121 (43%), Positives = 76/121 (62%), Gaps = 5/121 (4%)
Frame = -1
Query: 744 NLGGLMYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSFS-----VSXXXXXXXXXADAL 580
N+GG++ W ISLNAVSLVNLV+ G++VEF H+ +++ + +L
Sbjct: 1103 NIGGVLSLWDISLNAVSLVNLVICAGLAVEFTVHITRAYTNCNDIYNHANVKLLKAYHSL 1162
Query: 579 LRMGSSVLSGITLTKFGGIIVLATAKSQIFQVFYFRMYLGIVLFGAAHGLVFLPVMLSYI 400
+G SVL GITLTK G+ VLA +S+IF+V+YFRM+ ++ A H L LP++LSY
Sbjct: 1163 CTVGGSVLGGITLTKIIGMFVLAFTRSKIFEVYYFRMWFSLIFIAAVHALCLLPILLSYF 1222
Query: 399 G 397
G
Sbjct: 1223 G 1223
>UniRef50_Q01KH5 Cluster: H0409D10.4 protein; n=5; Eukaryota|Rep:
H0409D10.4 protein - Oryza sativa (Rice)
Length = 1372
Score = 107 bits (258), Expect = 2e-22
Identities = 59/135 (43%), Positives = 80/135 (59%), Gaps = 17/135 (12%)
Frame = -1
Query: 744 NLGGLMYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSFSVSXXXXXX------------ 601
+L G+M GI LNA+S+VNLVM++GI+VEFC H+ H+F +
Sbjct: 1138 DLMGMMAILGIQLNAISIVNLVMSIGIAVEFCVHITHAFMLFFSIVILKPLMTFFEMQIG 1197
Query: 600 -----XXXADALLRMGSSVLSGITLTKFGGIIVLATAKSQIFQVFYFRMYLGIVLFGAAH 436
AL MG+SV SGITLTK G+IVL AKS++F V+YF+MYL +V+ G H
Sbjct: 1198 IGNRESRARQALSTMGASVFSGITLTKLVGVIVLRFAKSEVFVVYYFQMYLALVIIGFLH 1257
Query: 435 GLVFLPVMLSYIGSP 391
GL+FLP ++ P
Sbjct: 1258 GLIFLPCYIATSSHP 1272
>UniRef50_Q5RJ13 Cluster: Novel protein; n=9; Euteleostomi|Rep: Novel
protein - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 827
Score = 107 bits (256), Expect = 4e-22
Identities = 51/115 (44%), Positives = 76/115 (66%)
Frame = -1
Query: 741 LGGLMYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSFSVSXXXXXXXXXADALLRMGSS 562
L G M W ISL++VS++NLV+ +G SV+F +H+ ++F S DAL ++G
Sbjct: 714 LAGFMALWDISLDSVSMINLVICIGFSVDFSAHISYAFVSSEKSSANEKATDALHKLGYP 773
Query: 561 VLSGITLTKFGGIIVLATAKSQIFQVFYFRMYLGIVLFGAAHGLVFLPVMLSYIG 397
++ G T G++VLA AKS IF+ F+ M+L ++LFGA HG+VFLPV LS++G
Sbjct: 774 IIQGAVST-IAGVVVLAAAKSYIFRTFFKIMFL-VILFGALHGIVFLPVFLSFLG 826
>UniRef50_A7SH24 Cluster: Predicted protein; n=5; Nematostella
vectensis|Rep: Predicted protein - Nematostella vectensis
Length = 881
Score = 105 bits (253), Expect = 9e-22
Identities = 57/125 (45%), Positives = 79/125 (63%)
Frame = -1
Query: 741 LGGLMYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSFSVSXXXXXXXXXADALLRMGSS 562
L LM W +SLNA+S++NLVMA+G SV++ +H+ H+F S AL +G+S
Sbjct: 707 LFALMSVWDVSLNAISMINLVMAIGFSVDYSAHIAHAFVTSSEPTAELRVEHALSTLGTS 766
Query: 561 VLSGITLTKFGGIIVLATAKSQIFQVFYFRMYLGIVLFGAAHGLVFLPVMLSYIGSPVNK 382
VL G ++ F G+IV + S+IF++F F+M+LGIVL G HGLVFLPV +S I
Sbjct: 767 VLLG-GISTFLGMIVTVGSSSKIFRIF-FKMFLGIVLLGLLHGLVFLPVYMSIICRWKVS 824
Query: 381 QKLAN 367
QK N
Sbjct: 825 QKARN 829
>UniRef50_UPI0000E7FCF0 Cluster: PREDICTED: hypothetical protein;
n=4; Gallus gallus|Rep: PREDICTED: hypothetical protein
- Gallus gallus
Length = 623
Score = 103 bits (246), Expect = 7e-21
Identities = 53/137 (38%), Positives = 85/137 (62%), Gaps = 5/137 (3%)
Frame = -1
Query: 741 LGGLMYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSFSVSXXXXXXXXXADALLRMGSS 562
+ G M +W ISL+++S++NLV+ +G SV+F +H+ ++F S AL ++G
Sbjct: 486 VSGFMTFWDISLDSISMINLVICIGFSVDFSAHISYAFVTSGESSANERAIGALHQLGYP 545
Query: 561 VLSGITLTKFGGIIVLATAKSQIFQVFYFRMYLGIVLFGAAHGLVFLPVMLSYIG----- 397
VL G T G++VLA AK+ IF+ F+ M+L ++LFGA HGLVF+PV L++ G
Sbjct: 546 VLQGAVSTVL-GVVVLAAAKTYIFRTFFKIMFL-VILFGALHGLVFIPVFLTFFGYFGKS 603
Query: 396 SPVNKQKLANQRRRGNE 346
PV + K+ + R R ++
Sbjct: 604 LPVTETKMLDLRYRNDK 620
>UniRef50_A0CEP2 Cluster: Chromosome undetermined scaffold_172, whole
genome shotgun sequence; n=3; Paramecium tetraurelia|Rep:
Chromosome undetermined scaffold_172, whole genome
shotgun sequence - Paramecium tetraurelia
Length = 912
Score = 92.7 bits (220), Expect = 9e-18
Identities = 48/114 (42%), Positives = 70/114 (61%)
Frame = -1
Query: 714 ISLNAVSLVNLVMAVGISVEFCSHLVHSFSVSXXXXXXXXXADALLRMGSSVLSGITLTK 535
I +NAVS+VNLV +G++VEF +H+V F + A+ MG+SV GI TK
Sbjct: 773 IEINAVSVVNLVTCIGLAVEFVAHIVIKFRLCEGKRWERVTG-AMSTMGTSVFVGIACTK 831
Query: 534 FGGIIVLATAKSQIFQVFYFRMYLGIVLFGAAHGLVFLPVMLSYIGSPVNKQKL 373
F G+ VL A S +F+++YFRMY+ +V+ GA +GLV LP+ L G + K+
Sbjct: 832 FIGVAVLGFAPSTLFKLYYFRMYILMVVLGAFNGLVLLPIFLGLFGPQFSIMKV 885
>UniRef50_Q9SHN9 Cluster: F7F22.1; n=2; Arabidopsis thaliana|Rep:
F7F22.1 - Arabidopsis thaliana (Mouse-ear cress)
Length = 1275
Score = 89.8 bits (213), Expect = 7e-17
Identities = 55/125 (44%), Positives = 75/125 (60%), Gaps = 25/125 (20%)
Frame = -1
Query: 714 ISLNAVSLVNLVMAVGISVEFCSH---------------LVHS-FSVSXXXXXXXXXA-- 589
I LNA+S+VNL+M+VGI+VEFC H ++H F++ +
Sbjct: 1108 IQLNALSVVNLIMSVGIAVEFCVHITHAFSVSPLSVCTSIIHKQFAIVTLTVRNAQISTG 1167
Query: 588 -------DALLRMGSSVLSGITLTKFGGIIVLATAKSQIFQVFYFRMYLGIVLFGAAHGL 430
+AL MG+SV SGITLTK G+IVL ++S++F V+YF+MYL +VL G HGL
Sbjct: 1168 DRNHRMKEALGGMGASVFSGITLTKLVGVIVLGFSRSEVFVVYYFKMYLALVLLGFLHGL 1227
Query: 429 VFLPV 415
VFLPV
Sbjct: 1228 VFLPV 1232
>UniRef50_Q4SP00 Cluster: Chromosome 15 SCAF14542, whole genome
shotgun sequence; n=3; Clupeocephala|Rep: Chromosome 15
SCAF14542, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 816
Score = 88.2 bits (209), Expect = 2e-16
Identities = 42/116 (36%), Positives = 73/116 (62%)
Frame = -1
Query: 741 LGGLMYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSFSVSXXXXXXXXXADALLRMGSS 562
+ G + WG++L++VS++NLVM G SV+F +H+ ++F S +AL R+G
Sbjct: 698 VAGFVALWGVNLDSVSMINLVMCTGFSVDFSAHVSYAFVSSSKTDIDGKAVEALARLGYP 757
Query: 561 VLSGITLTKFGGIIVLATAKSQIFQVFYFRMYLGIVLFGAAHGLVFLPVMLSYIGS 394
VL G L+ G+++L+ + S IF+ F+ ++L ++ FG H LVF+PV L+ +G+
Sbjct: 758 VLQG-ALSTILGVVLLSLSGSYIFRTFFKIIFL-VITFGLIHSLVFIPVFLTLLGA 811
>UniRef50_Q5CIB3 Cluster: F55F8.1; n=2; Cryptosporidium|Rep: F55F8.1 -
Cryptosporidium hominis
Length = 1281
Score = 87.8 bits (208), Expect = 3e-16
Identities = 44/115 (38%), Positives = 72/115 (62%)
Frame = -1
Query: 741 LGGLMYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSFSVSXXXXXXXXXADALLRMGSS 562
L G MY+W + LN VS++NL++++G +V++ + + H+FS ++L MG+
Sbjct: 1089 LFGFMYYWNVKLNMVSMINLLLSMGFAVDYSTLMTHTFSHCYGKTRNHRMIESLGLMGAP 1148
Query: 561 VLSGITLTKFGGIIVLATAKSQIFQVFYFRMYLGIVLFGAAHGLVFLPVMLSYIG 397
V G ++ F GI+VL+ + S IF VF F+M + +V FG HG V LP++LS +G
Sbjct: 1149 VCHG-AMSTFLGIVVLSGSSSYIFTVF-FKMMVMVVGFGIFHGAVVLPILLSLVG 1201
>UniRef50_A7RNK5 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella vectensis
Length = 1507
Score = 87.8 bits (208), Expect = 3e-16
Identities = 46/147 (31%), Positives = 85/147 (57%), Gaps = 1/147 (0%)
Frame = -1
Query: 744 NLGGLMYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSFSVSXXXXXXXXXADALLRMGS 565
+L G MY+WG++++ ++ + LV+AVG++V++ SH+ H F ++ + MG
Sbjct: 1306 DLCGFMYFWGLTIDTITTIQLVLAVGLAVDYSSHIGHMFMITPGTHEDRARI-TMRDMGP 1364
Query: 564 SVLSGITLTKFGGIIVLATAKSQIFQVFYFRMYLGIVLFGAAHGLVFLPVMLSYIG-SPV 388
+VL+G + F ++LA + S IF VF F+++ +VLFG HG+ +LPV+LS IG +P
Sbjct: 1365 AVLNG-GFSTFLAFVLLAASDSYIFGVF-FKIFFLVVLFGMWHGMAYLPVLLSSIGPAPY 1422
Query: 387 NKQKLANQRRRGNETTVAESSLTRVHL 307
+++++ + + V L
Sbjct: 1423 LSAQVSDRHNKSGRASPVHPKSENVEL 1449
>UniRef50_UPI00003650C0 Cluster: patched domain containing 3; n=1;
Takifugu rubripes|Rep: patched domain containing 3 -
Takifugu rubripes
Length = 844
Score = 87.4 bits (207), Expect = 4e-16
Identities = 41/112 (36%), Positives = 71/112 (63%)
Frame = -1
Query: 735 GLMYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSFSVSXXXXXXXXXADALLRMGSSVL 556
G M WG++L+++S++NLVM G SV+F +H+ ++F S DAL R+G +L
Sbjct: 735 GFMALWGVNLDSISMINLVMCTGFSVDFSAHVSYAFVSSSKTDVNKKATDALARLGYPIL 794
Query: 555 SGITLTKFGGIIVLATAKSQIFQVFYFRMYLGIVLFGAAHGLVFLPVMLSYI 400
G L+ G+++L+ + S IF+ F+ ++L ++ G HGLVF+PV+L+ +
Sbjct: 795 QG-ALSTILGVVLLSLSGSYIFRTFFKVIFL-VITSGLIHGLVFIPVILTLL 844
>UniRef50_Q86P36 Cluster: RE45036p; n=7; Endopterygota|Rep: RE45036p -
Drosophila melanogaster (Fruit fly)
Length = 1169
Score = 86.6 bits (205), Expect = 6e-16
Identities = 42/115 (36%), Positives = 69/115 (60%)
Frame = -1
Query: 741 LGGLMYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSFSVSXXXXXXXXXADALLRMGSS 562
+ G M W ++L+++S++NL+M +G SV+F +H+ +++ S +AL +G
Sbjct: 745 VAGYMALWDVNLDSISMINLIMCIGFSVDFTAHICYTYMSSKKRSPKARVREALHSLGLP 804
Query: 561 VLSGITLTKFGGIIVLATAKSQIFQVFYFRMYLGIVLFGAAHGLVFLPVMLSYIG 397
++ G + T GI+ L A+S IF VF F+M ++ FGA HGL LPV+LS G
Sbjct: 805 IIQGSSSTIL-GIVALLLAQSYIFLVF-FKMVFLVIFFGAMHGLFLLPVLLSLFG 857
>UniRef50_Q4PE83 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 1489
Score = 83.8 bits (198), Expect = 4e-15
Identities = 45/125 (36%), Positives = 73/125 (58%), Gaps = 10/125 (8%)
Frame = -1
Query: 741 LGGLMYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSF-----SVSXXXXXXXXXAD--- 586
+ G M +WGI NA++LVNL + I VEFC+H+ +F ++ D
Sbjct: 1320 VAGAMGFWGIQFNALTLVNLSVCAAIGVEFCAHIARAFMRAPGALPRSHPMSQKERDERA 1379
Query: 585 --ALLRMGSSVLSGITLTKFGGIIVLATAKSQIFQVFYFRMYLGIVLFGAAHGLVFLPVM 412
AL +GS+V++GI TK G+ VL KS + +++Y + +L +++ G HGL+ LPV+
Sbjct: 1380 WLALTDVGSAVVNGIFSTKLIGVGVLIFTKSDLLKLYYAKTWLCLIVGGLLHGLILLPVL 1439
Query: 411 LSYIG 397
LS++G
Sbjct: 1440 LSWLG 1444
>UniRef50_A0A5F1 Cluster: Patched family protein,; n=1; Toxoplasma
gondii RH|Rep: Patched family protein, - Toxoplasma
gondii RH
Length = 225
Score = 83.4 bits (197), Expect = 6e-15
Identities = 39/120 (32%), Positives = 74/120 (61%)
Frame = -1
Query: 735 GLMYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSFSVSXXXXXXXXXADALLRMGSSVL 556
G M++W + LN +++VNL++++G S+++ +H+ H+F + L+ +G+ +
Sbjct: 77 GFMHFWDLPLNMLTMVNLIISIGFSIDYATHICHTFCHCVGRTRDLRVFETLVLIGNPIF 136
Query: 555 SGITLTKFGGIIVLATAKSQIFQVFYFRMYLGIVLFGAAHGLVFLPVMLSYIGSPVNKQK 376
G+ L+ G+ VLA +S + +VF F+M ++ AHG++ LPV+LS IG P+N +K
Sbjct: 137 HGL-LSTLLGVSVLAFTRSYVLRVF-FKMMTLVLSLAFAHGVILLPVLLSLIG-PMNSRK 193
>UniRef50_UPI00015B5B0C Cluster: PREDICTED: similar to conserved
hypothetical protein; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to conserved hypothetical protein -
Nasonia vitripennis
Length = 957
Score = 82.2 bits (194), Expect = 1e-14
Identities = 45/139 (32%), Positives = 78/139 (56%), Gaps = 7/139 (5%)
Frame = -1
Query: 735 GLMYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSF-------SVSXXXXXXXXXADALL 577
G MY+WG++++ VS + L +AVG+SV++ +H+ H+F S A+
Sbjct: 803 GFMYYWGLTIDIVSCIGLELAVGLSVDYAAHVAHAFLNAGEIAGASRRVDRSSRALKAMR 862
Query: 576 RMGSSVLSGITLTKFGGIIVLATAKSQIFQVFYFRMYLGIVLFGAAHGLVFLPVMLSYIG 397
+G++VL G T + +L+ +++ +F+ F F+++L +++FG HGL+FLPV+LS IG
Sbjct: 863 HIGAAVLFGAGSTLL-ALSLLSFSRAYVFRAF-FKIFLLVIVFGLWHGLLFLPVVLSTIG 920
Query: 396 SPVNKQKLANQRRRGNETT 340
N R E T
Sbjct: 921 PRSLHADFRNNTTRSVEMT 939
>UniRef50_A5APM6 Cluster: Putative uncharacterized protein; n=1; Vitis
vinifera|Rep: Putative uncharacterized protein - Vitis
vinifera (Grape)
Length = 1050
Score = 81.4 bits (192), Expect = 2e-14
Identities = 54/115 (46%), Positives = 67/115 (58%)
Frame = -1
Query: 744 NLGGLMYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSFSVSXXXXXXXXXADALLRMGS 565
+L G+M I LNA+S+VNLVMAVGI+VEFC H+ H+FSVS D RM
Sbjct: 942 DLMGVMAILNIQLNALSVVNLVMAVGIAVEFCVHITHAFSVS--------SGDRNQRMKE 993
Query: 564 SVLSGITLTKFGGIIVLATAKSQIFQVFYFRMYLGIVLFGAAHGLVFLPVMLSYI 400
+ L T + +FQV+YF+MYL +VL G HGLVFLPV SYI
Sbjct: 994 A---------------LGTMGASVFQVYYFQMYLALVLLGFLHGLVFLPV--SYI 1031
>UniRef50_Q9XXR9 Cluster: Putative uncharacterized protein ptr-19;
n=2; Caenorhabditis|Rep: Putative uncharacterized protein
ptr-19 - Caenorhabditis elegans
Length = 1003
Score = 81.0 bits (191), Expect = 3e-14
Identities = 45/127 (35%), Positives = 73/127 (57%), Gaps = 4/127 (3%)
Frame = -1
Query: 744 NLG--GLMYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSFSVSXXXXXXXXXADALLRM 571
N+G G M +W + L+ +S+V +VM++G V+F +HL ++F+ +AL +
Sbjct: 744 NIGILGFMTFWSVRLDFISMVTIVMSIGFCVDFAAHLAYNFAKGQNMDGSERMRNALYAV 803
Query: 570 GSSVLSGITLTKFGGIIVLATAKSQIFQVFYFRMYLGIVLFGAAHGLVFLPVMLS--YIG 397
G+ +L T T G+ +A+A+S +F+ F + L ++L GA HGLV LPV+LS Y G
Sbjct: 804 GAPILMSATSTII-GVSFMASAESYVFRSFLKTIML-VILLGALHGLVILPVLLSMFYCG 861
Query: 396 SPVNKQK 376
K K
Sbjct: 862 GSSKKAK 868
>UniRef50_A5E1Z8 Cluster: Putative uncharacterized protein; n=1;
Lodderomyces elongisporus NRRL YB-4239|Rep: Putative
uncharacterized protein - Lodderomyces elongisporus
(Yeast) (Saccharomyces elongisporus)
Length = 1191
Score = 77.0 bits (181), Expect = 5e-13
Identities = 33/69 (47%), Positives = 51/69 (73%)
Frame = -1
Query: 588 DALLRMGSSVLSGITLTKFGGIIVLATAKSQIFQVFYFRMYLGIVLFGAAHGLVFLPVML 409
+AL+ +G S++ GIT+TK GI +LA +S+IF+V+YFRM+ +++ A H LV LP++L
Sbjct: 1090 NALVTVGGSIIGGITITKLIGITILAFTRSKIFEVYYFRMWFALIVIAAVHSLVLLPILL 1149
Query: 408 SYIGSPVNK 382
SY G +NK
Sbjct: 1150 SYFGD-LNK 1157
Score = 58.8 bits (136), Expect = 1e-07
Identities = 25/42 (59%), Positives = 34/42 (80%)
Frame = -1
Query: 744 NLGGLMYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSFSVS 619
N+GG+M WGISLNAVSLVNLV+ G++VEF H+ +++VS
Sbjct: 1004 NMGGMMSLWGISLNAVSLVNLVICCGLAVEFTIHITRAYTVS 1045
>UniRef50_Q18129 Cluster: Patched related family protein 1; n=2;
Caenorhabditis|Rep: Patched related family protein 1 -
Caenorhabditis elegans
Length = 956
Score = 76.6 bits (180), Expect = 7e-13
Identities = 41/130 (31%), Positives = 73/130 (56%)
Frame = -1
Query: 735 GLMYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSFSVSXXXXXXXXXADALLRMGSSVL 556
G M +WG++L++VS++ ++M +G SV+ +H+ ++FS S A AL +G V
Sbjct: 816 GFMSFWGVNLDSVSIITVIMCIGFSVDLSAHIAYAFSQSYGNSHARAVA-ALETLGWPVF 874
Query: 555 SGITLTKFGGIIVLATAKSQIFQVFYFRMYLGIVLFGAAHGLVFLPVMLSYIGSPVNKQK 376
G + T G I++L S I Q+F+ ++L ++ F HGL+FLP+ L + V ++
Sbjct: 875 LGASSTVLG-ILLLTLVDSYIVQIFFKTVFL-VINFSILHGLIFLPIFLMKVVREVKEES 932
Query: 375 LANQRRRGNE 346
+ + NE
Sbjct: 933 PRDDQSVENE 942
>UniRef50_Q7PXL5 Cluster: ENSANGP00000011713; n=2; Culicidae|Rep:
ENSANGP00000011713 - Anopheles gambiae str. PEST
Length = 627
Score = 76.2 bits (179), Expect = 9e-13
Identities = 37/116 (31%), Positives = 70/116 (60%)
Frame = -1
Query: 744 NLGGLMYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSFSVSXXXXXXXXXADALLRMGS 565
N+GGLM WG++L+ VS + L +AVG+ V++ +H+ H+F + +L +G+
Sbjct: 506 NVGGLMQVWGLTLDLVSCIALQLAVGLCVDYAAHIGHTFLTINKGDRNRRSLETVLHIGA 565
Query: 564 SVLSGITLTKFGGIIVLATAKSQIFQVFYFRMYLGIVLFGAAHGLVFLPVMLSYIG 397
+V G T + +L+ +++ ++ F F+++L ++ +G HG + LPV+LS IG
Sbjct: 566 AVFYGGGSTIL-SLSILSGSQAYTYRTF-FKIFLLVIAYGLFHGTILLPVILSLIG 619
>UniRef50_A2XWG3 Cluster: Putative uncharacterized protein; n=2; Oryza
sativa|Rep: Putative uncharacterized protein - Oryza
sativa subsp. indica (Rice)
Length = 1158
Score = 75.4 bits (177), Expect = 2e-12
Identities = 45/102 (44%), Positives = 58/102 (56%), Gaps = 17/102 (16%)
Frame = -1
Query: 735 GLMYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSFSVSXX-----------------XX 607
G+M GI LNA+S+VNLVM++GI+VEFC H+ H+F +
Sbjct: 999 GMMAILGIQLNAISIVNLVMSIGIAVEFCVHITHAFMLFFSIVILKPLMTFFEMQIGIGN 1058
Query: 606 XXXXXADALLRMGSSVLSGITLTKFGGIIVLATAKSQIFQVF 481
AL MG+SV SGITLTK G+IVL AKS++F VF
Sbjct: 1059 RESRARQALSTMGASVFSGITLTKLVGVIVLRFAKSEVFVVF 1100
>UniRef50_Q19945 Cluster: Putative uncharacterized protein daf-6; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein
daf-6 - Caenorhabditis elegans
Length = 913
Score = 74.1 bits (174), Expect = 4e-12
Identities = 39/115 (33%), Positives = 69/115 (60%), Gaps = 2/115 (1%)
Frame = -1
Query: 744 NLG--GLMYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSFSVSXXXXXXXXXADALLRM 571
N+G G M WG++L+AVS+++++M++G +V+ +H++++F V+ AL +
Sbjct: 786 NIGVFGYMTLWGVNLDAVSMISIIMSIGFAVDLSAHIIYAF-VTSHGDTKQRVIGALETL 844
Query: 570 GSSVLSGITLTKFGGIIVLATAKSQIFQVFYFRMYLGIVLFGAAHGLVFLPVMLS 406
G + G + T GI +L T + I VF+ ++L +L GA HGL F+P+ LS
Sbjct: 845 GWPIFQGASST-IAGISILYTVDAYIILVFFKTIWL-TMLIGAIHGLFFIPIFLS 897
>UniRef50_Q19127 Cluster: Niemann-Pick C1 protein homolog 1 precursor;
n=2; Caenorhabditis|Rep: Niemann-Pick C1 protein homolog
1 precursor - Caenorhabditis elegans
Length = 1383
Score = 73.7 bits (173), Expect = 5e-12
Identities = 36/112 (32%), Positives = 64/112 (57%)
Frame = -1
Query: 729 MYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSFSVSXXXXXXXXXADALLRMGSSVLSG 550
MY + I +NA+S NLVM+ GI +EF +++ ++ S + +G +LSG
Sbjct: 1174 MYIFNIPVNALSATNLVMSSGILIEFSVNVLKGYACSLRQRAKDRAESTVGSIGPIILSG 1233
Query: 549 ITLTKFGGIIVLATAKSQIFQVFYFRMYLGIVLFGAAHGLVFLPVMLSYIGS 394
+T G + L+ A QI V++F+++L ++ A H L+ LP++L++ GS
Sbjct: 1234 PVVTMAGSTMFLSGAHLQIITVYFFKLFLITIVSSAVHALIILPILLAFGGS 1285
>UniRef50_P91346 Cluster: Patched related family protein 10; n=2;
Caenorhabditis|Rep: Patched related family protein 10 -
Caenorhabditis elegans
Length = 900
Score = 72.5 bits (170), Expect = 1e-11
Identities = 37/114 (32%), Positives = 66/114 (57%), Gaps = 1/114 (0%)
Frame = -1
Query: 735 GLMYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSFSVSXXXXXXXXXADALLRMGSSVL 556
G M W ++L+A+S++ ++M+VG SV++ +H+ +++ +S DAL +G V
Sbjct: 768 GFMTLWNVNLDAISMITIIMSVGFSVDYSAHITYAYVISKESTTSARVCDALGDLGWPVA 827
Query: 555 SGITLTKFGGIIVLATAKSQIFQVFYFRMYLGIVLFGAAHGLVFLPVMLS-YIG 397
G T + VL+ + + F+ ++L I + G HGLVFLP+MLS ++G
Sbjct: 828 QGAMSTILA-VSVLSDVPAYMIVTFFKTVFLAISI-GFLHGLVFLPLMLSVFVG 879
>UniRef50_P34389 Cluster: Niemann-Pick C1 protein homolog 2 precursor;
n=2; Caenorhabditis|Rep: Niemann-Pick C1 protein homolog
2 precursor - Caenorhabditis elegans
Length = 1274
Score = 72.1 bits (169), Expect = 1e-11
Identities = 39/112 (34%), Positives = 62/112 (55%)
Frame = -1
Query: 729 MYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSFSVSXXXXXXXXXADALLRMGSSVLSG 550
MY GI++N VS++N+ M++GI+VEF ++H F S AL+ GS+ LSG
Sbjct: 1126 MYLLGITVNVVSVINMAMSLGIAVEFFGQMLHGFYNSKKPKREERAFAALVSNGSTTLSG 1185
Query: 549 ITLTKFGGIIVLATAKSQIFQVFYFRMYLGIVLFGAAHGLVFLPVMLSYIGS 394
I L+ A S++ ++ +GI L A HG+V++P +L+ GS
Sbjct: 1186 IFPAIMITAGCLSFADSRVLITYFCNQLVGIGLVCAVHGVVYMPTLLAIFGS 1237
>UniRef50_P91129 Cluster: Patched related family protein 2; n=2;
Caenorhabditis|Rep: Patched related family protein 2 -
Caenorhabditis elegans
Length = 933
Score = 71.7 bits (168), Expect = 2e-11
Identities = 37/110 (33%), Positives = 62/110 (56%)
Frame = -1
Query: 735 GLMYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSFSVSXXXXXXXXXADALLRMGSSVL 556
G M WG++L+A+S++ ++M++G SV++ +H+ + + VS +AL +G +
Sbjct: 747 GYMTLWGVNLDAISMITIIMSIGFSVDYSAHIAYGYVVSREDTAAGRVKEALSALGWPLS 806
Query: 555 SGITLTKFGGIIVLATAKSQIFQVFYFRMYLGIVLFGAAHGLVFLPVMLS 406
G T + VLA + + F+ + L I L G HGLVFLPV+LS
Sbjct: 807 QGAMSTIIA-VSVLADIPAYMIVTFFKTVVLSISL-GLLHGLVFLPVLLS 854
>UniRef50_Q007R7 Cluster: Patched protein; n=4; Eukaryota|Rep: Patched
protein - Lytechinus variegatus (Sea urchin)
Length = 1416
Score = 70.9 bits (166), Expect = 3e-11
Identities = 43/134 (32%), Positives = 69/134 (51%)
Frame = -1
Query: 741 LGGLMYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSFSVSXXXXXXXXXADALLRMGSS 562
L G M G+ L+A+ L+++VGI VEF H ++F ++ AL +
Sbjct: 1064 LFGFMGLIGLKLSAIPAATLIVSVGIGVEFTLHTCYAF-LTTIGNRERRVTFALEHTFAP 1122
Query: 561 VLSGITLTKFGGIIVLATAKSQIFQVFYFRMYLGIVLFGAAHGLVFLPVMLSYIGSPVNK 382
VL G T G +++LA A+ ++F ++L +++ G +GLV LPV+LS G
Sbjct: 1123 VLDGAVSTLLG-VVMLAGAEFDFIVSYFFYVFLALIILGVLNGLVLLPVLLSLFGPHGEV 1181
Query: 381 QKLANQRRRGNETT 340
Q +AN R + TT
Sbjct: 1182 QPVANANRLPSPTT 1195
>UniRef50_UPI0000DB6CB9 Cluster: PREDICTED: similar to PaTched Related
family member (ptr-19); n=1; Apis mellifera|Rep:
PREDICTED: similar to PaTched Related family member
(ptr-19) - Apis mellifera
Length = 881
Score = 68.5 bits (160), Expect = 2e-10
Identities = 35/120 (29%), Positives = 68/120 (56%), Gaps = 4/120 (3%)
Frame = -1
Query: 744 NLGGLMYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSF----SVSXXXXXXXXXADALL 577
N+ G MY+W ++++ VS + L + +G+ V++ +H+ H+F + A+
Sbjct: 729 NVCGFMYFWNLTIDIVSCIGLELGIGLCVDYAAHVAHAFINAACIDGSEDRTKRAHIAVR 788
Query: 576 RMGSSVLSGITLTKFGGIIVLATAKSQIFQVFYFRMYLGIVLFGAAHGLVFLPVMLSYIG 397
+G++V G T + ++A ++S +F F ++++ ++LFG HGL LPV+LS IG
Sbjct: 789 YIGAAVAYGAGSTLL-ALSMMAFSESYVFHAF-LKIFVLVILFGLWHGLFLLPVILSTIG 846
>UniRef50_Q09938 Cluster: Patched related family protein 6; n=2;
Caenorhabditis|Rep: Patched related family protein 6 -
Caenorhabditis elegans
Length = 982
Score = 67.7 bits (158), Expect = 3e-10
Identities = 39/132 (29%), Positives = 71/132 (53%), Gaps = 5/132 (3%)
Frame = -1
Query: 735 GLMYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSF-SVSXXXXXXXXXADALLRMGSSV 559
G + W + L+ +S++ ++M++G S+EF +H+ H F S DA+ ++ V
Sbjct: 833 GFLSLWSVKLDPISMITIIMSIGFSIEFSAHITHGFVSNDSNLSAFDRCVDAMEKLAWPV 892
Query: 558 LSGITLTKFGGIIVLATAKSQIFQVFYFRMYLGIVLFGAAHGLVFLPVMLSYIGSPVNK- 382
+ G +L+ G+ VLA S + VF+ + L +++ GA H L+ LP++LS + +
Sbjct: 893 VHG-SLSTILGVFVLAFIDSYMVLVFFKTISL-VLIIGAWHALMLLPILLSMCIPVIERL 950
Query: 381 ---QKLANQRRR 355
K A+ RRR
Sbjct: 951 SDASKKASDRRR 962
>UniRef50_Q09614 Cluster: Protein patched homolog 1; n=3;
Caenorhabditis|Rep: Protein patched homolog 1 -
Caenorhabditis elegans
Length = 1405
Score = 65.3 bits (152), Expect = 2e-09
Identities = 39/115 (33%), Positives = 63/115 (54%)
Frame = -1
Query: 741 LGGLMYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSFSVSXXXXXXXXXADALLRMGSS 562
L G M GI LN VS V L+ AVGI VEF H+V SF ++ + A+ R+
Sbjct: 1219 LAGFMGLVGIKLNPVSAVTLITAVGIGVEFTVHVVVSF-LTALGTRSQRTSSAVDRVFVP 1277
Query: 561 VLSGITLTKFGGIIVLATAKSQIFQVFYFRMYLGIVLFGAAHGLVFLPVMLSYIG 397
V+ G + + GI++L ++ + ++F + ++ G +GL+ LPV+LS+ G
Sbjct: 1278 VIHG-SFSTLLGILMLGFSEFEFVVKYFFIVMTALICIGIINGLILLPVLLSWFG 1331
>UniRef50_A7RK33 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella vectensis
Length = 1120
Score = 64.9 bits (151), Expect = 2e-09
Identities = 36/115 (31%), Positives = 63/115 (54%)
Frame = -1
Query: 741 LGGLMYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSFSVSXXXXXXXXXADALLRMGSS 562
L G M GI L+AV V L+++VG+ VEF H+ +F S A+ + +
Sbjct: 1003 LFGFMGLAGIKLSAVPAVTLILSVGVGVEFTVHMCMAFLTSTGDRNHRMQT-AIEHVFTP 1061
Query: 561 VLSGITLTKFGGIIVLATAKSQIFQVFYFRMYLGIVLFGAAHGLVFLPVMLSYIG 397
++ G T G +I+LA ++ ++F + +++ G+ +GL+FLPV+LS+ G
Sbjct: 1062 IVDGAVSTLLG-VIMLAGSEFDFIVRYFFHLLAALIVIGSLNGLMFLPVLLSFAG 1115
>UniRef50_Q4H2Z6 Cluster: Patched receptor; n=1; Ciona
intestinalis|Rep: Patched receptor - Ciona intestinalis
(Transparent sea squirt)
Length = 976
Score = 63.3 bits (147), Expect = 7e-09
Identities = 41/116 (35%), Positives = 63/116 (54%), Gaps = 1/116 (0%)
Frame = -1
Query: 735 GLMYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSFSVSXXXXXXXXXADALLRMGSSVL 556
G M G+ L+AV V LV ++G+ VEF H+ +F ++ ++ M V+
Sbjct: 582 GFMGAAGVKLSAVPAVILVASIGLGVEFTVHITFAF-ITSCGSRKERVVHSIGHMTGPVV 640
Query: 555 SGITLTKFGGIIVLATAKSQIFQVFYFRMYLGI-VLFGAAHGLVFLPVMLSYIGSP 391
G T G +++LA ++ F + YF LGI +L G +GLV LPV+LS+IG P
Sbjct: 641 DGAVSTLLG-VVMLAGSEFD-FIIKYFFQVLGILILLGVLNGLVLLPVVLSFIGPP 694
>UniRef50_Q9Y6C5 Cluster: Protein patched homolog 2; n=14; Theria|Rep:
Protein patched homolog 2 - Homo sapiens (Human)
Length = 1203
Score = 62.9 bits (146), Expect = 9e-09
Identities = 41/117 (35%), Positives = 60/117 (51%)
Frame = -1
Query: 741 LGGLMYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSFSVSXXXXXXXXXADALLRMGSS 562
L G+M + GI L+A+ +V LV +VGI VEF H+ F ++ A AL +
Sbjct: 1003 LFGIMGFLGIKLSAIPVVILVASVGIGVEFTVHVALGF-LTTQGSRNLRAAHALEHTFAP 1061
Query: 561 VLSGITLTKFGGIIVLATAKSQIFQVFYFRMYLGIVLFGAAHGLVFLPVMLSYIGSP 391
V G T G +++LA + ++F + L G HGLV LPV+LS +G P
Sbjct: 1062 VTDGAISTLLG-LLMLAGSHFDFIVRYFFAALTVLTLLGLLHGLVLLPVLLSILGPP 1117
>UniRef50_Q4RVD6 Cluster: Chromosome 15 SCAF14992, whole genome
shotgun sequence; n=3; Euteleostomi|Rep: Chromosome 15
SCAF14992, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 1197
Score = 62.5 bits (145), Expect = 1e-08
Identities = 40/117 (34%), Positives = 63/117 (53%)
Frame = -1
Query: 741 LGGLMYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSFSVSXXXXXXXXXADALLRMGSS 562
L G+M I L+A+ +V L+ +VGI VEF H+ F V+ A AL RM +
Sbjct: 1081 LFGVMGLINIKLSAIPVVILIASVGIGVEFTVHIAMGFLVATGNRNQRATA-ALERMFAP 1139
Query: 561 VLSGITLTKFGGIIVLATAKSQIFQVFYFRMYLGIVLFGAAHGLVFLPVMLSYIGSP 391
V G T G +++LA ++ + ++F + + + G +GLV LPV+LS +G P
Sbjct: 1140 VFDGAISTLLG-VLMLAGSEFEFIIRYFFAVLAILTVLGILNGLVLLPVLLSVLGPP 1195
>UniRef50_UPI00005882B2 Cluster: PREDICTED: similar to conserved
hypothetical protein, partial; n=1; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to conserved
hypothetical protein, partial - Strongylocentrotus
purpuratus
Length = 417
Score = 62.1 bits (144), Expect = 2e-08
Identities = 38/127 (29%), Positives = 63/127 (49%), Gaps = 14/127 (11%)
Frame = -1
Query: 735 GLMYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSFSVSXXXXXXXXXAD---------- 586
G M W + L+ +S++N+++ +G SV+F +H+ ++F S
Sbjct: 265 GYMSLWDVRLDGISMINIILCIGFSVDFSAHITYAFLSSNQALETIDHQHHHRKLSVAER 324
Query: 585 ----ALLRMGSSVLSGITLTKFGGIIVLATAKSQIFQVFYFRMYLGIVLFGAAHGLVFLP 418
AL +G +L G T +VL + S IF+ F+ M++ +VL G H L+FLP
Sbjct: 325 KAVMALYSLGMPILQGALSTILAN-VVLVFSPSYIFRTFFKIMFMVMVL-GMVHSLIFLP 382
Query: 417 VMLSYIG 397
V+LS G
Sbjct: 383 VLLSTFG 389
>UniRef50_Q9W6T6 Cluster: Patched-2 protein; n=7; Euteleostomi|Rep:
Patched-2 protein - Danio rerio (Zebrafish) (Brachydanio
rerio)
Length = 1243
Score = 62.1 bits (144), Expect = 2e-08
Identities = 44/129 (34%), Positives = 67/129 (51%)
Frame = -1
Query: 741 LGGLMYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSFSVSXXXXXXXXXADALLRMGSS 562
L G+M GI L+AV +V L+ +VGI VEF H+ +F + AL M +
Sbjct: 1081 LFGMMGLIGIKLSAVPVVILIASVGIGVEFTVHVALAFLTAIGDRNKRAVL-ALEHMFAP 1139
Query: 561 VLSGITLTKFGGIIVLATAKSQIFQVFYFRMYLGIVLFGAAHGLVFLPVMLSYIGSPVNK 382
VL G T G +++LA ++ ++F + + + G +GLV LPV+LSY G P +
Sbjct: 1140 VLDGAFSTLLG-VLMLAGSEFDFIVRYFFAVLAILTVLGVLNGLVLLPVLLSYFG-PCPE 1197
Query: 381 QKLANQRRR 355
A+ R R
Sbjct: 1198 VSPADGRSR 1206
>UniRef50_A4SBF8 Cluster: RND family transporter: Patched (Ptc)
segmentation polarity protein; n=2; Ostreococcus|Rep: RND
family transporter: Patched (Ptc) segmentation polarity
protein - Ostreococcus lucimarinus CCE9901
Length = 1183
Score = 62.1 bits (144), Expect = 2e-08
Identities = 36/112 (32%), Positives = 59/112 (52%)
Frame = -1
Query: 741 LGGLMYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSFSVSXXXXXXXXXADALLRMGSS 562
L G M + + LN S+ NL+++ G+ EF +H+ +F S + A +
Sbjct: 1075 LFGAMGRFNVKLNGASMANLIISTGVVNEFIAHMSRAFFSSDRRAGAAFASIAPALFNAG 1134
Query: 561 VLSGITLTKFGGIIVLATAKSQIFQVFYFRMYLGIVLFGAAHGLVFLPVMLS 406
V T F G+I A A+ + F+V++F + I+LF A+G+VFLP+ LS
Sbjct: 1135 V------TTFLGVIPSAFARYEYFRVYFFSQWCVILLFAVANGVVFLPIALS 1180
>UniRef50_Q13635 Cluster: Protein patched homolog 1; n=79;
Vertebrata|Rep: Protein patched homolog 1 - Homo sapiens
(Human)
Length = 1447
Score = 61.3 bits (142), Expect = 3e-08
Identities = 39/115 (33%), Positives = 61/115 (53%)
Frame = -1
Query: 741 LGGLMYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSFSVSXXXXXXXXXADALLRMGSS 562
L G+M GI L+AV +V L+ +VGI VEF H+ +F + AL M +
Sbjct: 1067 LFGMMGLIGIKLSAVPVVILIASVGIGVEFTVHVALAFLTAIGDKNRRAVL-ALEHMFAP 1125
Query: 561 VLSGITLTKFGGIIVLATAKSQIFQVFYFRMYLGIVLFGAAHGLVFLPVMLSYIG 397
VL G T G +++LA ++ ++F + + + G +GLV LPV+LS+ G
Sbjct: 1126 VLDGAVSTLLG-VLMLAGSEFDFIVRYFFAVLAILTILGVLNGLVLLPVLLSFFG 1179
>UniRef50_Q6AW16 Cluster: Patched family protein 3, isoform b; n=3;
Caenorhabditis|Rep: Patched family protein 3, isoform b -
Caenorhabditis elegans
Length = 1361
Score = 60.1 bits (139), Expect = 6e-08
Identities = 36/115 (31%), Positives = 58/115 (50%)
Frame = -1
Query: 741 LGGLMYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSFSVSXXXXXXXXXADALLRMGSS 562
LGG M GI +N +S V L+ AVGI VEF +H+ +F ++ L M
Sbjct: 1177 LGGFMGLMGIKMNPISAVTLICAVGIGVEFTAHVELAF-LTALGTIDQRLESCLQHMFVP 1235
Query: 561 VLSGITLTKFGGIIVLATAKSQIFQVFYFRMYLGIVLFGAAHGLVFLPVMLSYIG 397
V G ++ F G+++L ++ ++F +V G +GL LPV+L+ +G
Sbjct: 1236 VYHG-AISTFLGVVMLVFSEFDFVVTYFFYTMTLLVALGVFNGLCVLPVILTLVG 1289
>UniRef50_UPI00015B5B2F Cluster: PREDICTED: similar to putative
hedgehog receptor; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to putative hedgehog receptor -
Nasonia vitripennis
Length = 1791
Score = 58.8 bits (136), Expect = 1e-07
Identities = 39/113 (34%), Positives = 62/113 (54%)
Frame = -1
Query: 735 GLMYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSFSVSXXXXXXXXXADALLRMGSSVL 556
G+M GI L+AV V LV++VGISV F H+ SF V+ AL M + V+
Sbjct: 1504 GIMGLCGIKLSAVPAVLLVVSVGISVHFTVHICLSF-VTCVGSRDRRVRLALEHMYAPVV 1562
Query: 555 SGITLTKFGGIIVLATAKSQIFQVFYFRMYLGIVLFGAAHGLVFLPVMLSYIG 397
G LT +++LA ++ + ++F + + ++ G +GL F P++LS IG
Sbjct: 1563 HG-ALTTLLAVLMLAFSEFEFIVRYFFLVLVCLIGVGLVNGLFFFPILLSLIG 1614
>UniRef50_Q5CVL3 Cluster: Niemann-Pick type C1 disease protein/
patched like cholesterol transporter of the SecD family,
12 transmembrane domain; n=2; Cryptosporidium|Rep:
Niemann-Pick type C1 disease protein/ patched like
cholesterol transporter of the SecD family, 12
transmembrane domain - Cryptosporidium parvum Iowa II
Length = 1465
Score = 57.2 bits (132), Expect = 4e-07
Identities = 32/109 (29%), Positives = 60/109 (55%)
Frame = -1
Query: 732 LMYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSFSVSXXXXXXXXXADALLRMGSSVLS 553
+MY G+ + V+ + L AV S+E+ H+ H F ++ D+LL MG +V+
Sbjct: 1324 IMYITGLIFDIVAFMVLATAVSFSIEYIVHITHLFLLTKRNSGVERIRDSLLDMGPNVIY 1383
Query: 552 GITLTKFGGIIVLATAKSQIFQVFYFRMYLGIVLFGAAHGLVFLPVMLS 406
+ ++ F G+I+LA + S+ F+VF + + ++ A G++ P +LS
Sbjct: 1384 AV-ISTFLGVILLAFSTSESFKVFLWITTI-VLCVSATAGIMIAPAILS 1430
>UniRef50_Q9XWL9 Cluster: Putative uncharacterized protein ptr-18;
n=2; Caenorhabditis|Rep: Putative uncharacterized protein
ptr-18 - Caenorhabditis elegans
Length = 858
Score = 53.2 bits (122), Expect = 7e-06
Identities = 34/115 (29%), Positives = 56/115 (48%), Gaps = 2/115 (1%)
Frame = -1
Query: 744 NLG--GLMYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSFSVSXXXXXXXXXADALLRM 571
NLG G + + I L+ +S+ L+MA+G SV+F +H+ + AL +
Sbjct: 682 NLGVFGCLVYMNIDLDPISMTTLLMAIGFSVDFVAHITWHYYKGDFHSKRARIRHALAGI 741
Query: 570 GSSVLSGITLTKFGGIIVLATAKSQIFQVFYFRMYLGIVLFGAAHGLVFLPVMLS 406
+ T T I VLA + + QVF ++ + ++ G HGLV LP++ S
Sbjct: 742 AWPMFQAGTSTML-AITVLALVHAYMVQVF-VKVVVLVIFLGMFHGLVVLPIVFS 794
>UniRef50_Q5DTE5 Cluster: Putative uncharacterized protein ptr-17;
n=4; Caenorhabditis|Rep: Putative uncharacterized protein
ptr-17 - Caenorhabditis elegans
Length = 936
Score = 51.6 bits (118), Expect = 2e-05
Identities = 33/115 (28%), Positives = 58/115 (50%), Gaps = 6/115 (5%)
Frame = -1
Query: 735 GLMYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSF------SVSXXXXXXXXXADALLR 574
G M + G+SL+A S++ + M+VG SV+F +H+ +++ + L
Sbjct: 804 GTMSFLGVSLDATSMITVAMSVGFSVDFAAHVSYAYMTESGAQIPGKSAIYSRFCHTLGT 863
Query: 573 MGSSVLSGITLTKFGGIIVLATAKSQIFQVFYFRMYLGIVLFGAAHGLVFLPVML 409
+G V +++ G+ L S + Q FR + ++LFG H LVFLP++L
Sbjct: 864 IGWPVTQA-SVSVLLGVSSLYLVDSYVVQT-CFRTVVLVILFGTTHALVFLPLLL 916
>UniRef50_Q09934 Cluster: Putative uncharacterized protein ptr-13;
n=2; Caenorhabditis|Rep: Putative uncharacterized protein
ptr-13 - Caenorhabditis elegans
Length = 851
Score = 51.6 bits (118), Expect = 2e-05
Identities = 35/123 (28%), Positives = 62/123 (50%), Gaps = 3/123 (2%)
Frame = -1
Query: 735 GLMYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSFSVS---XXXXXXXXXADALLRMGS 565
G + WG +L+ V++++++MA+G SV++ +H+ + + + L +G
Sbjct: 712 GFLSIWGQNLDPVTMIDVIMAIGFSVDYSAHVCYHYYCAREQHLGSKHEVITSVLQAVGR 771
Query: 564 SVLSGITLTKFGGIIVLATAKSQIFQVFYFRMYLGIVLFGAAHGLVFLPVMLSYIGSPVN 385
V+ +LT + L + Q F + L + FG HGL FLPV+L +I P+N
Sbjct: 772 PVVEA-SLTTLLCMAPLFVVPVYMIQSFAKTVTL-VTSFGLLHGLFFLPVVLYFI--PLN 827
Query: 384 KQK 376
QK
Sbjct: 828 AQK 830
>UniRef50_Q9U1R3 Cluster: Putative uncharacterized protein ptr-22;
n=2; Caenorhabditis|Rep: Putative uncharacterized protein
ptr-22 - Caenorhabditis elegans
Length = 859
Score = 51.2 bits (117), Expect = 3e-05
Identities = 30/111 (27%), Positives = 53/111 (47%)
Frame = -1
Query: 735 GLMYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSFSVSXXXXXXXXXADALLRMGSSVL 556
G + WG+ ++ VS +L+M++G SV+ +H+ + + +G L
Sbjct: 696 GFLSIWGVGMDPVSTASLLMSIGFSVDISAHISYHYYQVDKPTARQKLEHVYSHIGWPTL 755
Query: 555 SGITLTKFGGIIVLATAKSQIFQVFYFRMYLGIVLFGAAHGLVFLPVMLSY 403
G L+ ++ + A S + VF + L + FG HGL+ LPV LS+
Sbjct: 756 QG-GLSTMLAMMPIVLAPSYLGMVFLKTVIL-VCTFGLIHGLIVLPVFLSF 804
>UniRef50_Q95YD0 Cluster: Patched related family protein 4; n=2;
Caenorhabditis|Rep: Patched related family protein 4 -
Caenorhabditis elegans
Length = 960
Score = 50.8 bits (116), Expect = 4e-05
Identities = 32/111 (28%), Positives = 58/111 (52%)
Frame = -1
Query: 738 GGLMYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSFSVSXXXXXXXXXADALLRMGSSV 559
GGL G L++VS+ +VMA+G++V++ H+ + + S AD L +G V
Sbjct: 827 GGLALL-GSDLDSVSMGCIVMAIGLAVDYSVHICYRYHRSEYKTAQEKVADTLASVGWPV 885
Query: 558 LSGITLTKFGGIIVLATAKSQIFQVFYFRMYLGIVLFGAAHGLVFLPVMLS 406
+ T G + + + + +VF+ +YL + + G H LV+LP ++S
Sbjct: 886 TQAVCSTLVG-LAITVFVPAYLVRVFFQTVYL-VNIIGLFHALVWLPQLIS 934
>UniRef50_Q010M7 Cluster: Predicted membrane protein; n=3;
Eukaryota|Rep: Predicted membrane protein - Ostreococcus
tauri
Length = 1449
Score = 50.4 bits (115), Expect = 5e-05
Identities = 32/112 (28%), Positives = 55/112 (49%)
Frame = -1
Query: 732 LMYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSFSVSXXXXXXXXXADALLRMGSSVLS 553
++ + G+ V ++L + VGISV+F HL +F+ S DA+ R+G + S
Sbjct: 1234 ILVYLGVKFGIVEAISLTILVGISVDFSLHLAEAFTRSHFTTRGLRGVDAVSRVGYPIFS 1293
Query: 552 GITLTKFGGIIVLATAKSQIFQVFYFRMYLGIVLFGAAHGLVFLPVMLSYIG 397
LT ++ + + + QI F + L I++ A+GL F ML +G
Sbjct: 1294 A-ALTTMSAVLPMLSCEIQILVRFGQIIPLCIIM-SLAYGLHFFAPMLMALG 1343
>UniRef50_Q4T1E7 Cluster: Chromosome 12 SCAF10644, whole genome
shotgun sequence; n=2; Euteleostomi|Rep: Chromosome 12
SCAF10644, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 1075
Score = 36.7 bits (81), Expect(2) = 5e-05
Identities = 15/44 (34%), Positives = 27/44 (61%)
Frame = -1
Query: 528 GIIVLATAKSQIFQVFYFRMYLGIVLFGAAHGLVFLPVMLSYIG 397
G+++LA ++ ++F + + + G +GLV LPV+LSY G
Sbjct: 859 GVLMLAGSEFDFIVRYFFAVLAILTILGVLNGLVLLPVLLSYFG 902
Score = 33.1 bits (72), Expect(2) = 5e-05
Identities = 17/34 (50%), Positives = 22/34 (64%)
Frame = -1
Query: 741 LGGLMYWWGISLNAVSLVNLVMAVGISVEFCSHL 640
L G M GI L+AV +V L+ +VGI VEF H+
Sbjct: 823 LFGFMGLMGIKLSAVPVVILIASVGIGVEFTVHV 856
>UniRef50_O16307 Cluster: Patched related family protein 16; n=2;
Caenorhabditis|Rep: Patched related family protein 16 -
Caenorhabditis elegans
Length = 881
Score = 49.2 bits (112), Expect = 1e-04
Identities = 32/115 (27%), Positives = 58/115 (50%), Gaps = 3/115 (2%)
Frame = -1
Query: 744 NLG--GLMYWWGISLNAVSLVNLVMAVGISVEFCSHL-VHSFSVSXXXXXXXXXADALLR 574
N+G GL+ W ++L+ +++ +M++G SV+F +H+ H + ADAL
Sbjct: 649 NIGVFGLLSMWRVNLDPITMCTTLMSIGFSVDFTAHISYHYYRNPTSWTTDERLADALKS 708
Query: 573 MGSSVLSGITLTKFGGIIVLATAKSQIFQVFYFRMYLGIVLFGAAHGLVFLPVML 409
+G ++ + T I L S + VF + L + + G HG++FLP +L
Sbjct: 709 IGWPMIQAASSTVL-CIFPLMFNTSYMVWVF-VKTILLVTVLGLLHGIIFLPALL 761
>UniRef50_UPI0000DA314A Cluster: PREDICTED: similar to Ptc-related
CG11212-PA; n=13; Tetrapoda|Rep: PREDICTED: similar to
Ptc-related CG11212-PA - Rattus norvegicus
Length = 904
Score = 48.4 bits (110), Expect = 2e-04
Identities = 29/130 (22%), Positives = 59/130 (45%)
Frame = -1
Query: 735 GLMYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSFSVSXXXXXXXXXADALLRMGSSVL 556
GLM W + ++ +S++ L+ + +++ C+ L+++F ++ +L G+++L
Sbjct: 759 GLMTLWNVDMDCISILCLIYTLNFAIDHCAPLLYTFVLATEHTRTQCIKSSLQEHGTAIL 818
Query: 555 SGITLTKFGGIIVLATAKSQIFQVFYFRMYLGIVLFGAAHGLVFLPVMLSYIGSPVNKQK 376
IT G + +L + F +F + G H V LPV L++ P K
Sbjct: 819 QNITSFLIGLVPLLFVPSNLTFTLFKCLLLTGGCTL--LHCFVILPVFLTFF-PPSKKHH 875
Query: 375 LANQRRRGNE 346
+R + E
Sbjct: 876 KKKKRAKRKE 885
>UniRef50_O61894 Cluster: Patched related family protein 15; n=2;
Caenorhabditis|Rep: Patched related family protein 15 -
Caenorhabditis elegans
Length = 840
Score = 48.4 bits (110), Expect = 2e-04
Identities = 28/109 (25%), Positives = 55/109 (50%)
Frame = -1
Query: 735 GLMYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSFSVSXXXXXXXXXADALLRMGSSVL 556
GL+ WG L+ +++VN++M++G ++F +H+ S DA+ +G V+
Sbjct: 719 GLLSLWGADLDPMTVVNILMSIGQCIDFATHVGIRIYRSEYSDPDERIRDAMGAIGWPVV 778
Query: 555 SGITLTKFGGIIVLATAKSQIFQVFYFRMYLGIVLFGAAHGLVFLPVML 409
T T +++L S + + R + +V G HGL+ LP+++
Sbjct: 779 QAGTSTLLAIVVMLMVPSSAV--RMFARTSVLVVGTGFFHGLIILPIIV 825
>UniRef50_O16530 Cluster: Patched related family protein 3; n=2;
Caenorhabditis|Rep: Patched related family protein 3 -
Caenorhabditis elegans
Length = 914
Score = 48.4 bits (110), Expect = 2e-04
Identities = 31/134 (23%), Positives = 58/134 (43%), Gaps = 1/134 (0%)
Frame = -1
Query: 735 GLMYWWGISLNAVSLVNLVMAVGISVEFCSHL-VHSFSVSXXXXXXXXXADALLRMGSSV 559
G+M WWG L+ + + VM++G SV+ SH+ H + + +
Sbjct: 778 GIMSWWGADLDPIMMSATVMSIGFSVDIPSHVSYHFYQTAKDTSDIRRRLQMTIEAVGFP 837
Query: 558 LSGITLTKFGGIIVLATAKSQIFQVFYFRMYLGIVLFGAAHGLVFLPVMLSYIGSPVNKQ 379
+ +L+ ++ L + Q+F M L +V+ G HG++ +PV+ + + + K
Sbjct: 838 IFEASLSTSLCVMSLFFVDLNMAQIFAKCMLL-VVVIGMVHGMLVMPVIFALLDTVPRKL 896
Query: 378 KLANQRRRGNETTV 337
K Q T V
Sbjct: 897 KPRKQHLASTVTVV 910
>UniRef50_Q03602 Cluster: Patched-related protein 9; n=2;
Caenorhabditis|Rep: Patched-related protein 9 -
Caenorhabditis elegans
Length = 844
Score = 48.4 bits (110), Expect = 2e-04
Identities = 31/103 (30%), Positives = 51/103 (49%)
Frame = -1
Query: 708 LNAVSLVNLVMAVGISVEFCSHLVHSFSVSXXXXXXXXXADALLRMGSSVLSGITLTKFG 529
L+ +S++ +VM+VG SV++ +H F + LL M +L T G
Sbjct: 719 LDIISMITIVMSVGFSVDYVTHTTFHFVIQRDNRLEK----CLLVMTEPILQSALSTAIG 774
Query: 528 GIIVLATAKSQIFQVFYFRMYLGIVLFGAAHGLVFLPVMLSYI 400
+ +L+ S I + F ++ +V G HGL+FLPV+L I
Sbjct: 775 -VSLLSFVHSYIVRTFVNTVFF-VVGLGILHGLIFLPVLLDTI 815
>UniRef50_A7RP60 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella vectensis
Length = 1098
Score = 48.0 bits (109), Expect = 3e-04
Identities = 32/107 (29%), Positives = 50/107 (46%)
Frame = -1
Query: 717 GISLNAVSLVNLVMAVGISVEFCSHLVHSFSVSXXXXXXXXXADALLRMGSSVLSGITLT 538
G L + +NL + VG++V++ HL + S DAL +G SVLSG T
Sbjct: 936 GWKLGVLESLNLTLVVGLAVDYVVHLADGYVRSHNHFRGDKTRDALGSVGISVLSG-ACT 994
Query: 537 KFGGIIVLATAKSQIFQVFYFRMYLGIVLFGAAHGLVFLPVMLSYIG 397
G + + AK F F M+ I L ++ L+F +L+ +G
Sbjct: 995 TLGASVFMLAAKIVFFFQFGIFMFCTIGL-SISYALLFFTTLLALVG 1040
>UniRef50_UPI0000E48C80 Cluster: PREDICTED: similar to Fbxw9
protein; n=2; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to Fbxw9 protein - Strongylocentrotus
purpuratus
Length = 810
Score = 47.6 bits (108), Expect = 4e-04
Identities = 24/72 (33%), Positives = 42/72 (58%), Gaps = 1/72 (1%)
Frame = -1
Query: 570 GSSVLSGITLTKFGGIIVLAT-AKSQIFQVFYFRMYLGIVLFGAAHGLVFLPVMLSYIGS 394
G ++L+ L + VLAT + ++ V++F ++L +++ G +GLV LPV+LS G
Sbjct: 518 GENILTQSALLQHVRSAVLATQVEVDMYGVYFFYVFLALIILGVLNGLVLLPVLLSLFGP 577
Query: 393 PVNKQKLANQRR 358
P + +AN R
Sbjct: 578 PGEVRPVANANR 589
>UniRef50_Q21883 Cluster: Putative uncharacterized protein ptr-14;
n=2; Caenorhabditis|Rep: Putative uncharacterized protein
ptr-14 - Caenorhabditis elegans
Length = 877
Score = 44.4 bits (100), Expect = 0.003
Identities = 33/114 (28%), Positives = 55/114 (48%), Gaps = 5/114 (4%)
Frame = -1
Query: 735 GLMYWWGISLNAVSLVNLVMAVGISVEFCSHLV-HSFSVSX---XXXXXXXXADALLRMG 568
G + WGI L+ +S+ L+M++G SV+F +H+ H F A +L +G
Sbjct: 723 GFLSMWGIDLDPISMACLIMSIGFSVDFPAHITFHYFREGLHDPQSTPAKRVARSLAAIG 782
Query: 567 SSVLS-GITLTKFGGIIVLATAKSQIFQVFYFRMYLGIVLFGAAHGLVFLPVML 409
+L G++ F ++ L + + +VF M L +V G HGL +P L
Sbjct: 783 FPLLQCGLSTILF--VLCLLFVPTYMGEVFVKTMIL-VVTLGLIHGLFIVPAFL 833
>UniRef50_O02246 Cluster: Putative uncharacterized protein ptr-23;
n=2; Caenorhabditis|Rep: Putative uncharacterized protein
ptr-23 - Caenorhabditis elegans
Length = 983
Score = 44.4 bits (100), Expect = 0.003
Identities = 30/118 (25%), Positives = 54/118 (45%), Gaps = 4/118 (3%)
Frame = -1
Query: 735 GLMYWWGISLNAVSLVNLVMAVGISVEFCSHL-VHSFSVSXXXXXXXXXADALLRMGSSV 559
G + WW + L+ +++ +++++G SV+ +H+ H + S + L SSV
Sbjct: 823 GFLSWWKVDLDPITMAAMIISIGFSVDIPAHVSYHYYQASIQEGPMSPPSSRLANCLSSV 882
Query: 558 LSGITLTKFGGIIVLAT---AKSQIFQVFYFRMYLGIVLFGAAHGLVFLPVMLSYIGS 394
I+ + + + +VF M L +VL HGLVFLP +L + S
Sbjct: 883 AFPALQAALSTILCVCSLLFVNLYMAEVFVKTMVLCVVLCNL-HGLVFLPAILILLDS 939
>UniRef50_Q00U42 Cluster: Novel protein; n=2; Ostreococcus|Rep:
Novel protein - Ostreococcus tauri
Length = 853
Score = 42.3 bits (95), Expect = 0.013
Identities = 13/39 (33%), Positives = 33/39 (84%)
Frame = -1
Query: 744 NLGGLMYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSF 628
N+ G M++WG+++++V+++ LV+A+G+SV++ +H+ ++
Sbjct: 773 NIVGYMHFWGLTIDSVTVIMLVIALGLSVDYSAHIGRAY 811
>UniRef50_Q9NAB5 Cluster: Putative uncharacterized protein ptr-20;
n=2; Caenorhabditis|Rep: Putative uncharacterized protein
ptr-20 - Caenorhabditis elegans
Length = 860
Score = 42.3 bits (95), Expect = 0.013
Identities = 29/116 (25%), Positives = 56/116 (48%), Gaps = 10/116 (8%)
Frame = -1
Query: 729 MYWWGISLNAVSLVNLVMAVGISVEFCSHL-------VHSFSVSXXXXXXXXXADALLRM 571
++ W ++L+AVSL++++M++G SV++ +H+ VH D LL
Sbjct: 718 LHLWNVNLDAVSLISMLMSIGFSVDYSAHVCYHYFAHVHEDEQLWRSHNYAETRDRLLST 777
Query: 570 GSSVLSGIT---LTKFGGIIVLATAKSQIFQVFYFRMYLGIVLFGAAHGLVFLPVM 412
V + L+ G+ L ++ + VF+ + L + + G H L+ LPV+
Sbjct: 778 FRGVAWPVMQSGLSTILGMFPLMFVRAYVVAVFWKTVIL-VGILGMLHALILLPVI 832
>UniRef50_Q09540 Cluster: Patched family protein 2; n=1;
Caenorhabditis elegans|Rep: Patched family protein 2 -
Caenorhabditis elegans
Length = 667
Score = 41.9 bits (94), Expect = 0.018
Identities = 28/71 (39%), Positives = 36/71 (50%)
Frame = -1
Query: 741 LGGLMYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSFSVSXXXXXXXXXADALLRMGSS 562
L G M GI LN VS V L+ AVGI VEF H+V SF ++ + A+ R+
Sbjct: 590 LAGFMGLVGIKLNPVSAVTLITAVGIGVEFTVHVVVSF-LTALGTRSQRTSSAVDRVFVP 648
Query: 561 VLSGITLTKFG 529
V+ G T G
Sbjct: 649 VIHGSFSTLLG 659
>UniRef50_A1U382 Cluster: Transport protein, putative; n=1;
Marinobacter aquaeolei VT8|Rep: Transport protein,
putative - Marinobacter aquaeolei (strain ATCC 700491 /
DSM 11845 / VT8)(Marinobacter hydrocarbonoclasticus
(strain DSM 11845))
Length = 825
Score = 40.7 bits (91), Expect = 0.040
Identities = 30/118 (25%), Positives = 46/118 (38%), Gaps = 1/118 (0%)
Frame = -1
Query: 735 GLMYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSFSVS-XXXXXXXXXADALLRMGSSV 559
GLM W GI L+ +++ + VGI+V+ H +H F R
Sbjct: 708 GLMGWLGIPLDMMTITVAAITVGIAVDDTIHYIHRFKTEFAKDGDYLATMHRCHRSIGQA 767
Query: 558 LSGITLTKFGGIIVLATAKSQIFQVFYFRMYLGIVLFGAAHGLVFLPVMLSYIGSPVN 385
+ +LT G +L S YF ++ G +F A G + L L + P N
Sbjct: 768 MFYTSLTIIAGFSILVL--SNFIPTIYFGLFTGFAMFMALLGALTLLPRLIILVRPFN 823
>UniRef50_O44978 Cluster: Patched related family protein 11; n=2;
Caenorhabditis|Rep: Patched related family protein 11 -
Caenorhabditis elegans
Length = 820
Score = 40.7 bits (91), Expect = 0.040
Identities = 30/112 (26%), Positives = 53/112 (47%)
Frame = -1
Query: 741 LGGLMYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSFSVSXXXXXXXXXADALLRMGSS 562
+GGL W G L+ V V++++A G SV++ +H+ ++F +L M
Sbjct: 680 VGGLSLW-GADLDPVIQVDVLLATGFSVDYTAHVAYNF-FRARGTPQERVYSSLAEMAMP 737
Query: 561 VLSGITLTKFGGIIVLATAKSQIFQVFYFRMYLGIVLFGAAHGLVFLPVMLS 406
+ L+ F ++ L + F ++L +V G HGL LPV+L+
Sbjct: 738 MCEA-GLSTFLCMLPLIFVPTYAIVCFAKTVFL-VVAIGLLHGLFILPVILA 787
>UniRef50_Q12II7 Cluster: Cation/multidrug efflux pump-like protein
precursor; n=1; Shewanella denitrificans OS217|Rep:
Cation/multidrug efflux pump-like protein precursor -
Shewanella denitrificans (strain OS217 / ATCC BAA-1090 /
DSM 15013)
Length = 1018
Score = 39.9 bits (89), Expect = 0.071
Identities = 27/115 (23%), Positives = 56/115 (48%), Gaps = 2/115 (1%)
Frame = -1
Query: 738 GGLMYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSFSVSXXXXXXXXXADALLRMGSSV 559
G +MY+ G+ +N +SL + +++G+ ++ +V + A + S+
Sbjct: 366 GAIMYFSGVGINLLSLGAMSVSIGMVIDGAIVVVDNIYYHQKKQTGVGVFGATREVAPSI 425
Query: 558 LSGI--TLTKFGGIIVLATAKSQIFQVFYFRMYLGIVLFGAAHGLVFLPVMLSYI 400
L+ + T+ F + + S + + F + + I+LF LVFLPV+LS++
Sbjct: 426 LASVITTIIVFLPMAFTSPIASALLRDIAF-VVVSIMLFSVFVNLVFLPVILSFL 479
>UniRef50_UPI0000E4A16C Cluster: PREDICTED: similar to dispatched 1;
n=3; Strongylocentrotus purpuratus|Rep: PREDICTED:
similar to dispatched 1 - Strongylocentrotus purpuratus
Length = 980
Score = 39.1 bits (87), Expect = 0.12
Identities = 39/133 (29%), Positives = 62/133 (46%), Gaps = 1/133 (0%)
Frame = -1
Query: 717 GISLNAVSLVNLVMAVGISVEFCSHLVHSFSVSXXXXXXXXXADALLRMGSSV-LSGITL 541
G LN L +AVG+SV+F HL ++ + AL +GS+V L+ +T
Sbjct: 828 GWELNIFESTVLSLAVGLSVDFTVHLGVAYRQATESDRTSRSMHALQTLGSAVTLAALTT 887
Query: 540 TKFGGIIVLATAKSQIFQVFYFRMYLGIVLFGAAHGLVFLPVMLSYIGSPVNKQKLANQR 361
GG ++ AT S + Q+ F M + +V + +GL FL + L P ++
Sbjct: 888 LVAGGCMLPATVLSYV-QLGTFLMIVMVVSW--VYGL-FLFISLCRTIGPQGMFAQISKS 943
Query: 360 RRGNETTVAESSL 322
E VAE++L
Sbjct: 944 CCCREQNVAENNL 956
>UniRef50_P91184 Cluster: Patched related family protein 5; n=2;
Caenorhabditis|Rep: Patched related family protein 5 -
Caenorhabditis elegans
Length = 961
Score = 39.1 bits (87), Expect = 0.12
Identities = 30/128 (23%), Positives = 56/128 (43%), Gaps = 12/128 (9%)
Frame = -1
Query: 735 GLMYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSFSVSXXXXXXXXXADALLRMGSSVL 556
G + W L+ V + ++M++G+SV+F +H+ + F ++ + GS+
Sbjct: 792 GFLSLWSFDLDPVVMAAVLMSIGLSVDFIAHVAYHFQLAHRKEIRNGKIKKIPLKGSTER 851
Query: 555 SGITLTKF------GGIIVLATAKSQIFQ------VFYFRMYLGIVLFGAAHGLVFLPVM 412
TL G+ + +F+ VF ++L +V FG HGL+ LP
Sbjct: 852 LEHTLGAVAWPMIQAGVSTICCILPLLFRASYSPSVFVAAIFL-VVTFGMLHGLLILPTF 910
Query: 411 LSYIGSPV 388
L+ + V
Sbjct: 911 LAALPESV 918
>UniRef50_Q5VTU9 Cluster: Patched domain-containing protein 2; n=24;
Tetrapoda|Rep: Patched domain-containing protein 2 - Homo
sapiens (Human)
Length = 1438
Score = 39.1 bits (87), Expect = 0.12
Identities = 15/35 (42%), Positives = 23/35 (65%)
Frame = -1
Query: 732 LMYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSF 628
+MYW G + AV ++L + VG SV++C HLV +
Sbjct: 1271 IMYWSGWEMGAVEAISLSILVGSSVDYCVHLVEGY 1305
>UniRef50_Q54MS4 Cluster: Putative uncharacterized protein; n=2;
Eukaryota|Rep: Putative uncharacterized protein -
Dictyostelium discoideum AX4
Length = 911
Score = 38.7 bits (86), Expect = 0.16
Identities = 18/63 (28%), Positives = 32/63 (50%)
Frame = +1
Query: 361 PLVGQLLFVNRRTDIAEHNRQEYESVGRTEQHNPEVHPEVEHLEDLALGRGEHDDAAELG 540
P+V LL+++ + + A + E+V E+H+ V E E +D + HDD +
Sbjct: 759 PIVSNLLYIHSKKNAAFFKNKPQETVQHNEKHDDTVQQEEEKEDDTIQHKQTHDDTVQHK 818
Query: 541 ERD 549
E+D
Sbjct: 819 EKD 821
>UniRef50_Q1N6G9 Cluster: Membrane protein, putative; n=2;
Gammaproteobacteria|Rep: Membrane protein, putative -
Oceanobacter sp. RED65
Length = 849
Score = 37.5 bits (83), Expect = 0.38
Identities = 29/122 (23%), Positives = 55/122 (45%), Gaps = 2/122 (1%)
Frame = -1
Query: 735 GLMYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSFSVSXXXXXXXXXADALLRMGSSVL 556
G+M W G+ L+ +++ +A+GI+V+ H +H F +A+ R +S+
Sbjct: 730 GVMGWAGMPLDMMTITIAAIAIGIAVDDTIHYIHRF--KEEFVEHRNYEEAIRRCHASIG 787
Query: 555 SGITLTKFGGIIVLA-TAKSQIFQVFYFRMYLGI-VLFGAAHGLVFLPVMLSYIGSPVNK 382
+ T I+ + A S YF + G+ +L L LP M+ + P+ +
Sbjct: 788 KAVYYTSITVIVGFSILALSNFIPTIYFGLLTGLAMLIALVLVLTLLPRMI-LMFKPLGE 846
Query: 381 QK 376
+K
Sbjct: 847 EK 848
>UniRef50_Q5RIV7 Cluster: Patched domain-containing protein 1; n=33;
Euteleostomi|Rep: Patched domain-containing protein 1 -
Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 897
Score = 37.1 bits (82), Expect = 0.50
Identities = 24/126 (19%), Positives = 60/126 (47%)
Frame = -1
Query: 735 GLMYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSFSVSXXXXXXXXXADALLRMGSSVL 556
GLM W + ++++S++ L+ + +++ C+ +++F ++ +L G+++L
Sbjct: 742 GLMTLWNVDMDSISILCLIYTLNFAMDHCAPHLYTFVLATEHTRTQCIKISLEEHGAAIL 801
Query: 555 SGITLTKFGGIIVLATAKSQIFQVFYFRMYLGIVLFGAAHGLVFLPVMLSYIGSPVNKQK 376
+ G + +L + + + F+ L H V LPV L++ P +K++
Sbjct: 802 QNTSCFVIGIMPLLFVPSNLTYTL--FKCSLLTAGCTVLHCFVILPVFLTFF--PPSKKR 857
Query: 375 LANQRR 358
++R
Sbjct: 858 HKKKKR 863
>UniRef50_UPI0000E470D2 Cluster: PREDICTED: hypothetical protein,
partial; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: hypothetical protein, partial -
Strongylocentrotus purpuratus
Length = 71
Score = 36.7 bits (81), Expect = 0.66
Identities = 13/31 (41%), Positives = 22/31 (70%)
Frame = -1
Query: 483 FYFRMYLGIVLFGAAHGLVFLPVMLSYIGSP 391
++F ++L +++ G +GLV LPV+LS G P
Sbjct: 39 YFFYVFLALIILGVLNGLVLLPVLLSLFGPP 69
>UniRef50_Q2AGZ0 Cluster: Hydrophobe/amphiphile efflux-3 HAE3
precursor; n=1; Halothermothrix orenii H 168|Rep:
Hydrophobe/amphiphile efflux-3 HAE3 precursor -
Halothermothrix orenii H 168
Length = 764
Score = 36.3 bits (80), Expect = 0.87
Identities = 26/126 (20%), Positives = 57/126 (45%), Gaps = 3/126 (2%)
Frame = -1
Query: 735 GLMYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSF--SVSXXXXXXXXXADALLRMGSS 562
G M W GI+L+ V+++ + VG+ +++ H+ + ++ G S
Sbjct: 642 GTMGWSGIALDIVTVLISSIGVGVGIDYSIHIYSRYLEEKKKGFSVEEALKTSVRTTGIS 701
Query: 561 VLSGITLTKFGGIIVLATAKSQIFQVFYFRMYLGIVLFGAAHG-LVFLPVMLSYIGSPVN 385
++ G ++L + F+ YF M + +++ A+ G ++++P M+ +
Sbjct: 702 IIVNAGAV-ISGFVILTISSFPPFR--YFGMLVSLIMLVASSGAMLWIPAMIIFADRFKT 758
Query: 384 KQKLAN 367
K KL N
Sbjct: 759 KIKLKN 764
>UniRef50_Q8D4H9 Cluster: Cation/multidrug efflux pump; n=13;
Gammaproteobacteria|Rep: Cation/multidrug efflux pump -
Vibrio vulnificus
Length = 1033
Score = 35.9 bits (79), Expect = 1.2
Identities = 32/130 (24%), Positives = 64/130 (49%), Gaps = 8/130 (6%)
Frame = -1
Query: 741 LGGL--MYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSFSVSXXXXXXXXXADALLRMG 568
LGGL M G+S+N +SLV L+MA+GI ++ +V + S++ DA+++
Sbjct: 364 LGGLFLMAQLGLSINIMSLVGLLMAIGIMMD--DAIVIAESIAAHLDRGEKIDDAVIKGV 421
Query: 567 SSVLSGI------TLTKFGGIIVLATAKSQIFQVFYFRMYLGIVLFGAAHGLVFLPVMLS 406
+ VL G+ T+ FG ++ L + + ++ + ++ + LP +
Sbjct: 422 NKVLPGVISSFLTTVCIFGSLLFLQGEMGAVLKAVP-QVLILVLTLSLVEAFLILP---N 477
Query: 405 YIGSPVNKQK 376
++ ++KQK
Sbjct: 478 HLAHSLHKQK 487
>UniRef50_Q5V7L9 Cluster: Putative lipid/cholesterol transport; n=2;
Halobacteriaceae|Rep: Putative lipid/cholesterol
transport - Haloarcula marismortui (Halobacterium
marismortui)
Length = 823
Score = 35.1 bits (77), Expect = 2.0
Identities = 28/107 (26%), Positives = 47/107 (43%), Gaps = 1/107 (0%)
Frame = -1
Query: 735 GLMYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSFSVSXXXXXXXXXADALLRMGS-SV 559
G M + GISLNA++ L +++G+ + + H H F + + G+
Sbjct: 696 GTMRYLGISLNALTGTILSISIGLGIAYSVHATHRFVDEYNAGADAYESIIITFSGTGGA 755
Query: 558 LSGITLTKFGGIIVLATAKSQIFQVFYFRMYLGIVLFGAAHGLVFLP 418
L G LT G LA A + + F M + V++ A ++ LP
Sbjct: 756 LLGSMLTTSLGTGALALAITPVLGDFGLLMAIS-VIYSFAFTIIALP 801
>UniRef50_Q21L50 Cluster: Patched; n=2; Gammaproteobacteria|Rep:
Patched - Saccharophagus degradans (strain 2-40 / ATCC
43961 / DSM 17024)
Length = 778
Score = 34.7 bits (76), Expect = 2.7
Identities = 26/124 (20%), Positives = 60/124 (48%), Gaps = 3/124 (2%)
Frame = -1
Query: 738 GGLMYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSF-SVSXXXXXXXXXADALLRMG-- 568
GGL+ + G++++ +++ M +GI+V+ H++ + D ++
Sbjct: 656 GGLVSFAGVAIDLGTMIVGAMTIGIAVDDSIHIMSRYLQYRKQGKSTREAIDGAMQSAGR 715
Query: 567 SSVLSGITLTKFGGIIVLATAKSQIFQVFYFRMYLGIVLFGAAHGLVFLPVMLSYIGSPV 388
+ +L+ I L +++L + S I+ + + +G+ L G L+F+P +L Y+
Sbjct: 716 AVILTSIILISGFSVMLLGSFVSYIYVGLFSAIIMGLALAG---DLIFMPALL-YLFDNS 771
Query: 387 NKQK 376
K+K
Sbjct: 772 EKKK 775
>UniRef50_A1ZFX3 Cluster: Membrane protein, putative; n=1; Microscilla
marina ATCC 23134|Rep: Membrane protein, putative -
Microscilla marina ATCC 23134
Length = 761
Score = 34.7 bits (76), Expect = 2.7
Identities = 29/125 (23%), Positives = 51/125 (40%), Gaps = 3/125 (2%)
Frame = -1
Query: 741 LGGLMYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSFSV--SXXXXXXXXXADALLRMG 568
+ G+M + G+SL + + +A GI+V+ H + + + G
Sbjct: 640 IAGIMGYAGLSLKLSTTIVFTIAFGIAVDDTIHFLSKLRIELNKGTSLLYAIKSTYFSAG 699
Query: 567 SSVLSGITLTKFGGIIVLATAKSQIFQVFYFRMYLGIVLFGAA-HGLVFLPVMLSYIGSP 391
+++ +L GG ++L A S FY + + I L A L LP +L
Sbjct: 700 KAIVL-TSLVLCGGFLIL--AMSSFLGTFYLGLLVSITLLMAVISDLFLLPALLILTAPS 756
Query: 390 VNKQK 376
NK+K
Sbjct: 757 SNKKK 761
>UniRef50_Q9N2Z6 Cluster: Patched related family protein 21; n=2;
Caenorhabditis|Rep: Patched related family protein 21 -
Caenorhabditis elegans
Length = 909
Score = 34.7 bits (76), Expect = 2.7
Identities = 26/121 (21%), Positives = 57/121 (47%), Gaps = 11/121 (9%)
Frame = -1
Query: 735 GLMYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSFSVSXXXXXXXXXAD--ALLRMGSS 562
G + +W + L+ V+L +++++G+SV+F +H+ + V + S
Sbjct: 740 GYLCFWDLDLDPVTLCAVIVSIGMSVDFVAHVACHYQVRYKEFEEKGVLKRIEMKTPESR 799
Query: 561 VLSGIT-----LTKFGGIIVLATAKSQIFQ----VFYFRMYLGIVLFGAAHGLVFLPVML 409
V++ ++ + + +L I Q + + + L +V++G HGLV LP +L
Sbjct: 800 VVNSLSNVLWPMVQSASSTLLCVLPLGILQNYLPMVFVKTILLVVIWGMFHGLVLLPCIL 859
Query: 408 S 406
+
Sbjct: 860 A 860
>UniRef50_UPI0000E477D4 Cluster: PREDICTED: hypothetical protein; n=1;
Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 1422
Score = 34.3 bits (75), Expect = 3.5
Identities = 29/112 (25%), Positives = 51/112 (45%), Gaps = 1/112 (0%)
Frame = -1
Query: 732 LMYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSFSVSXXXXXXXXXADA-LLRMGSSVL 556
+ Y G + AV V+L + VG S+++C HLV + V+ A +R ++
Sbjct: 1253 MFYLLGWQMGAVEAVSLSILVGSSIDYCIHLVEGYRVAGCQVKMDSGKSARQIRQQRTIH 1312
Query: 555 SGITLTKFGGIIVLATAKSQIFQVFYFRMYLGIVLFGAAHGLVFLPVMLSYI 400
S T+ G+ +L++A + I + I LF +V L ++S I
Sbjct: 1313 SISTI----GVSILSSALTTIIAAIPL-CFTTIQLFAKFGQIVALNTLVSII 1359
>UniRef50_Q1IYF0 Cluster: Acriflavin resistance protein; n=1;
Deinococcus geothermalis DSM 11300|Rep: Acriflavin
resistance protein - Deinococcus geothermalis (strain
DSM 11300)
Length = 1123
Score = 34.3 bits (75), Expect = 3.5
Identities = 27/110 (24%), Positives = 50/110 (45%), Gaps = 5/110 (4%)
Frame = -1
Query: 717 GISLNAVSLVNLVMAVGISVEFCSHLVHSFSVSXXXXXXXXXADALLRMGSSVLSGITLT 538
G + N VSL+ L++A+GI V+ +V + +V +++LR S V S +
Sbjct: 388 GFTFNQVSLLALIVAIGIVVD--DSIVVAENVERYRTLGFGRVESVLRGASEVFSAVAAA 445
Query: 537 KFG--GIIVLATAKSQIFQVFYFRMYLGI---VLFGAAHGLVFLPVMLSY 403
+++ + I + + LG+ VL L+FL V ++Y
Sbjct: 446 SLSLLAVLIPVSFMGGIIGAYIQQFALGLAAAVLMSWLEALLFLTVRMAY 495
>UniRef50_Q0BSN4 Cluster: Cobalt-zinc-cadmium resistance protein
czcA; n=5; Proteobacteria|Rep: Cobalt-zinc-cadmium
resistance protein czcA - Granulobacter bethesdensis
(strain ATCC BAA-1260 / CGDNIH1)
Length = 1055
Score = 34.3 bits (75), Expect = 3.5
Identities = 19/76 (25%), Positives = 35/76 (46%)
Frame = -1
Query: 735 GLMYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSFSVSXXXXXXXXXADALLRMGSSVL 556
G+M WG+S N +SL L +A+G+ V+ +V + S LR+ +
Sbjct: 376 GVMRLWGLSANIMSLGGLAIAIGLLVDCAVVVVENASHRFTEAVRPPTFPQRLRLVAEST 435
Query: 555 SGITLTKFGGIIVLAT 508
+ + G+I++ T
Sbjct: 436 REVVVPLVSGVIIIVT 451
>UniRef50_Q21FB7 Cluster: Patched; n=3; Gammaproteobacteria|Rep:
Patched - Saccharophagus degradans (strain 2-40 / ATCC
43961 / DSM 17024)
Length = 872
Score = 33.9 bits (74), Expect = 4.6
Identities = 29/121 (23%), Positives = 50/121 (41%), Gaps = 3/121 (2%)
Frame = -1
Query: 735 GLMYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSF--SVSXXXXXXXXXADALLRMGSS 562
G+M G+ L+ +++ + VGI V+ H +H F + A +G +
Sbjct: 752 GIMGLGGLPLDMMTITIASITVGIGVDDTIHYIHRFKKEIVVDGDYIAAMHRAHASIGRA 811
Query: 561 VLSGITLTKFG-GIIVLATAKSQIFQVFYFRMYLGIVLFGAAHGLVFLPVMLSYIGSPVN 385
+ + FG I+VL S+ YF + G+ +F A G + L L + P
Sbjct: 812 MYYTSVIIIFGFSIMVL----SKFIPTIYFGLLTGVAMFAALMGALLLLPKLIILFKPFG 867
Query: 384 K 382
K
Sbjct: 868 K 868
>UniRef50_A7RP59 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella vectensis
Length = 1016
Score = 33.9 bits (74), Expect = 4.6
Identities = 27/113 (23%), Positives = 46/113 (40%)
Frame = -1
Query: 735 GLMYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSFSVSXXXXXXXXXADALLRMGSSVL 556
G + +G L + +NL + VG++V++ HL + L +G SV+
Sbjct: 854 GFITMFGWKLGVLESLNLTLVVGLAVDYVVHLADCYVNCPSACRLDRVKFTLGHVGISVI 913
Query: 555 SGITLTKFGGIIVLATAKSQIFQVFYFRMYLGIVLFGAAHGLVFLPVMLSYIG 397
SG T G + + AK F F ++ I L L ++L +G
Sbjct: 914 SG-ACTTLGAAMFMFAAKILFFFQFGAFIFCTIGL-SLLFSLFLFTILLGLVG 964
>UniRef50_Q0VPB5 Cluster: Transport protein, putative; n=1;
Alcanivorax borkumensis SK2|Rep: Transport protein,
putative - Alcanivorax borkumensis (strain SK2 / ATCC
700651 / DSM 11573)
Length = 886
Score = 33.5 bits (73), Expect = 6.1
Identities = 28/113 (24%), Positives = 48/113 (42%), Gaps = 4/113 (3%)
Frame = -1
Query: 735 GLMYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSFSVSXXXXXXXXXADALLRMGSSVL 556
GLM W G+ L+ +++ +++GI+V+ H +H F + R S+
Sbjct: 768 GLMGWIGLPLDLMTITITAISIGIAVDDTIHYIHRFHEELPKDHDYVA--TMKRCHGSIG 825
Query: 555 SGI---TLTKFGGIIVLATAKSQIFQVFYFRMYLGI-VLFGAAHGLVFLPVML 409
+ +LT G +LA S YF + G+ +L L LP +L
Sbjct: 826 KAMYYTSLTIIAGFSILAL--SSFNPTVYFGLLTGLAMLVALLSNLTLLPALL 876
>UniRef50_Q0SUR3 Cluster: Antibiotic ABC transporter, permease
protein; n=2; Clostridium|Rep: Antibiotic ABC
transporter, permease protein - Clostridium perfringens
(strain SM101 / Type A)
Length = 695
Score = 33.5 bits (73), Expect = 6.1
Identities = 25/121 (20%), Positives = 50/121 (41%), Gaps = 1/121 (0%)
Frame = -1
Query: 735 GLMYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSFSVSXXXXXXXXXADAL-LRMGSSV 559
G W+G ++ V+ +G+++++ L+H + A A+ +
Sbjct: 215 GTNIWFGDISYITKALSAVLQLGVTMDYSIFLLHRYEEEKLIEKDNVSAMAIAIEKTIGS 274
Query: 558 LSGITLTKFGGIIVLATAKSQIFQVFYFRMYLGIVLFGAAHGLVFLPVMLSYIGSPVNKQ 379
+SG +LT G + L + + + F M G++L G + LP + +NK
Sbjct: 275 ISGSSLTTIAGFLALCIMQLSLGKDIGFVMAKGVIL-GLICTITVLPAFILVFDKYINKF 333
Query: 378 K 376
K
Sbjct: 334 K 334
>UniRef50_UPI0000D8B388 Cluster: hornerin; n=2; Euteleostomi|Rep:
hornerin - Mus musculus
Length = 3609
Score = 33.1 bits (72), Expect = 8.1
Identities = 19/96 (19%), Positives = 30/96 (31%)
Frame = +1
Query: 391 RRTDIAEHNRQEYESVGRTEQHNPEVHPEVEHLEDLALGRGEHDDAAELGERDAGQHGRA 570
+R+ +H + Y +E + PE H + + GRG E G A G
Sbjct: 136 QRSSRGQHGSRYYYEQEHSEHQHEHEQPESGHRQQQSSGRGHQGAHQEQGRDSARSRGSN 195
Query: 571 HXXXXXXXXXXXXXXXXXXXXXXQVRAELHRYAHRH 678
Q R H++ H+H
Sbjct: 196 QGHSSSRHQADSPRVSARSGSHEQQRGHQHQHQHQH 231
>UniRef50_Q12M39 Cluster: Acriflavin resistance protein; n=1;
Shewanella denitrificans OS217|Rep: Acriflavin
resistance protein - Shewanella denitrificans (strain
OS217 / ATCC BAA-1090 / DSM 15013)
Length = 1063
Score = 33.1 bits (72), Expect = 8.1
Identities = 18/41 (43%), Positives = 27/41 (65%), Gaps = 2/41 (4%)
Frame = -1
Query: 741 LGGL--MYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSFS 625
LGGL M +G+S+N +SLV L+MA+GI ++ L S +
Sbjct: 364 LGGLYLMSLFGVSINMLSLVGLLMAIGIMMDDAIVLAESIA 404
>UniRef50_A1HR74 Cluster: 4-diphosphocytidyl-2C-methyl-D-erythritol
kinase; n=1; Thermosinus carboxydivorans Nor1|Rep:
4-diphosphocytidyl-2C-methyl-D-erythritol kinase -
Thermosinus carboxydivorans Nor1
Length = 287
Score = 33.1 bits (72), Expect = 8.1
Identities = 16/33 (48%), Positives = 19/33 (57%)
Frame = -1
Query: 741 LGGLMYWWGISLNAVSLVNLVMAVGISVEFCSH 643
L GL WG+SLN+ L L A+G V FC H
Sbjct: 108 LRGLNRLWGLSLNSRELEQLGAALGSDVPFCLH 140
>UniRef50_A0Z591 Cluster: Putative integral membrane protein; n=1;
marine gamma proteobacterium HTCC2080|Rep: Putative
integral membrane protein - marine gamma proteobacterium
HTCC2080
Length = 858
Score = 33.1 bits (72), Expect = 8.1
Identities = 29/122 (23%), Positives = 50/122 (40%), Gaps = 3/122 (2%)
Frame = -1
Query: 735 GLMYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSFSVSXXXXXXXXXADALLRMGSSV- 559
G+M +GI L+ +++ + VGI V+ C H +H F A+ R +S+
Sbjct: 738 GVMGLFGIPLDIMTITIAAIVVGIGVDDCIHYIHRFRGEFAIDRNYHA--AMRRSHASIG 795
Query: 558 --LSGITLTKFGGIIVLATAKSQIFQVFYFRMYLGIVLFGAAHGLVFLPVMLSYIGSPVN 385
+ TLT G +L S YF + + + A G + L L + P+
Sbjct: 796 RAMYYTTLTVMVGFSLLTL--SNFTPSLYFGLLTDLAMVAAVAGALLLLPQLILVFRPLG 853
Query: 384 KQ 379
+
Sbjct: 854 PE 855
>UniRef50_A0NQP7 Cluster: Zinc uptake ABC transporter,
substrate-binding protein; n=2; Alphaproteobacteria|Rep:
Zinc uptake ABC transporter, substrate-binding protein -
Stappia aggregata IAM 12614
Length = 365
Score = 33.1 bits (72), Expect = 8.1
Identities = 17/47 (36%), Positives = 21/47 (44%)
Frame = +1
Query: 424 EYESVGRTEQHNPEVHPEVEHLEDLALGRGEHDDAAELGERDAGQHG 564
E E G H+ + H E E A G +HDD A E D +HG
Sbjct: 147 EGEHAGDDHDHSADEHDHAEEHEK-AQGASDHDDHANEAEHDHAEHG 192
>UniRef50_Q18JY4 Cluster: Probable substrate efflux/proton antiporter;
n=4; Halobacteriaceae|Rep: Probable substrate
efflux/proton antiporter - Haloquadratum walsbyi (strain
DSM 16790)
Length = 821
Score = 33.1 bits (72), Expect = 8.1
Identities = 27/112 (24%), Positives = 44/112 (39%), Gaps = 1/112 (0%)
Frame = -1
Query: 741 LGGLMYWWGISLNAVSLVNLVMAVGISVEFCSHLVHSFSVS-XXXXXXXXXADALLRMGS 565
L M + I N ++ L + +G+ +++ +H VH F+ +R
Sbjct: 697 LASTMRYLDIPFNVLTGTTLSVGIGLGIDYSAHFVHRFTEEYRGEVDRFEALSVSVRGTG 756
Query: 564 SVLSGITLTKFGGIIVLATAKSQIFQVFYFRMYLGIVLFGAAHGLVFLPVML 409
L+G LT G VL A + I F + L VL+ + LP L
Sbjct: 757 GALAGSMLTTTSGTGVLILAITPILGQFGLLIALS-VLYSFIASIFVLPAAL 807
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 618,220,830
Number of Sequences: 1657284
Number of extensions: 11127632
Number of successful extensions: 33182
Number of sequences better than 10.0: 113
Number of HSP's better than 10.0 without gapping: 31966
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 33079
length of database: 575,637,011
effective HSP length: 99
effective length of database: 411,565,895
effective search space used: 66673674990
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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