Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fcaL-P09_F_L03
(732 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X06825-1|CAA29971.1| 284|Homo sapiens protein ( Human mRNA for ... 206 6e-53
AL133410-4|CAI10977.1| 284|Homo sapiens tropomyosin 2 (beta) pr... 206 6e-53
AL133410-3|CAI10976.1| 322|Homo sapiens tropomyosin 2 (beta) pr... 206 6e-53
AL133410-1|CAI10975.1| 284|Homo sapiens tropomyosin 2 (beta) pr... 206 6e-53
M19713-1|AAA61225.1| 284|Homo sapiens TPM1 protein. 204 2e-52
AY640415-1|AAT68295.1| 284|Homo sapiens tropomyosin alpha stria... 204 3e-52
X04201-1|CAA27798.1| 285|Homo sapiens protein ( Human skeletal ... 200 4e-51
BC008425-1|AAH08425.1| 285|Homo sapiens tropomyosin 3 protein. 200 4e-51
BC008407-1|AAH08407.1| 285|Homo sapiens tropomyosin 3 protein. 200 4e-51
AL590431-12|CAH71269.1| 284|Homo sapiens tropomyosin 3 protein. 200 4e-51
AK023385-1|BAB14554.1| 284|Homo sapiens protein ( Homo sapiens ... 200 5e-51
M75165-1|AAB59509.1| 284|Homo sapiens tropomyosin protein. 198 1e-50
M74817-1|AAA61230.1| 284|Homo sapiens tropomyosin-1 protein. 198 1e-50
M12125-1|AAA36773.1| 284|Homo sapiens protein ( Human fibroblas... 198 1e-50
BC011776-1|AAH11776.1| 284|Homo sapiens tropomyosin 2 (beta) pr... 198 1e-50
AL133410-2|CAI10974.1| 284|Homo sapiens tropomyosin 2 (beta) pr... 198 1e-50
AF209746-1|AAF17621.1| 257|Homo sapiens beta tropomyosin protein. 198 1e-50
M19267-1|AAA36771.1| 284|Homo sapiens protein ( Human tropomyos... 198 2e-50
BC007433-1|AAH07433.1| 284|Homo sapiens tropomyosin 1 (alpha) p... 198 2e-50
AK223258-1|BAD96978.1| 284|Homo sapiens tropomyosin 2 (beta) is... 196 5e-50
AY640414-1|AAT68294.1| 284|Homo sapiens sarcomeric tropomyosin ... 188 1e-47
AK131384-1|BAD18535.1| 326|Homo sapiens protein ( Homo sapiens ... 175 1e-43
M19714-1|AAA61226.1| 264|Homo sapiens TPM1 protein. 172 1e-42
BC053545-1|AAH53545.1| 245|Homo sapiens tropomyosin 1 (alpha) p... 150 6e-36
BC050473-1|AAH50473.1| 287|Homo sapiens TPM1 protein protein. 150 6e-36
Z24727-1|CAA80853.1| 243|Homo sapiens tropomyosin isoform protein. 148 2e-35
AB209041-1|BAD92278.1| 303|Homo sapiens TPM1 protein variant pr... 147 4e-35
AL590431-10|CAH71268.1| 247|Homo sapiens tropomyosin 3 protein. 146 7e-35
AL590431-9|CAH71267.1| 248|Homo sapiens tropomyosin 3 protein. 146 7e-35
M19715-1|AAA61227.1| 229|Homo sapiens TPM1 protein. 146 9e-35
X05276-1|CAA28888.1| 248|Homo sapiens protein ( Human mRNA for ... 144 3e-34
BT019634-1|AAV38440.1| 248|Homo sapiens tropomyosin 4 protein. 144 3e-34
BC067225-1|AAH67225.1| 248|Homo sapiens tropomyosin 4 protein. 144 3e-34
BC037576-1|AAH37576.1| 248|Homo sapiens tropomyosin 4 protein. 144 3e-34
AF310722-1|AAK17926.1| 320|Homo sapiens tropomyosin 4-anaplasti... 144 3e-34
AF186109-1|AAG17014.1| 237|Homo sapiens TPM4-ALK fusion oncopro... 144 3e-34
DQ424903-1|ABD83668.1| 245|Homo sapiens tropomyosin 1 alpha var... 143 5e-34
BC002827-1|AAH02827.1| 248|Homo sapiens tropomyosin 4 protein. 143 7e-34
AF474156-1|AAL84569.1| 203|Homo sapiens TPMsk1 protein. 141 2e-33
AL590431-11|CAH71270.1| 242|Homo sapiens tropomyosin 3 protein. 139 1e-32
AK092690-1|BAC03946.1| 243|Homo sapiens protein ( Homo sapiens ... 139 1e-32
X12369-1|CAA30930.1| 227|Homo sapiens tropomyosin (227 AA) prot... 136 8e-32
X04588-1|CAB37185.1| 248|Homo sapiens protein ( Human 2.5 kb mR... 135 2e-31
BC072428-1|AAH72428.1| 248|Homo sapiens tropomyosin 3 protein. 135 2e-31
BC015403-1|AAH15403.1| 248|Homo sapiens tropomyosin 3 protein. 135 2e-31
BC000771-1|AAH00771.1| 248|Homo sapiens tropomyosin 3 protein. 135 2e-31
AY004867-1|AAF87083.1| 247|Homo sapiens tropomyosin isoform pro... 135 2e-31
AL590431-8|CAH71264.1| 248|Homo sapiens tropomyosin 3 protein. 135 2e-31
AL590431-7|CAH71266.1| 248|Homo sapiens tropomyosin 3 protein. 135 2e-31
AF474157-1|AAL84570.1| 247|Homo sapiens TPMsk3 protein. 135 2e-31
X03541-1|CAA27243.1| 641|Homo sapiens protein ( Human mRNA of t... 133 5e-31
AK129882-1|BAC85248.1| 217|Homo sapiens protein ( Homo sapiens ... 131 2e-30
DQ120714-1|ABC40673.1| 247|Homo sapiens rcTPM3 protein. 129 9e-30
AL590431-5|CAH71263.1| 224|Homo sapiens tropomyosin 3 protein. 105 2e-22
AL590431-6|CAH71265.1| 232|Homo sapiens tropomyosin 3 protein. 99 8e-21
AF186110-1|AAG17015.1| 227|Homo sapiens TPM4-ALK fusion oncopro... 89 2e-17
BC062740-1|AAH62740.1| 158|Homo sapiens TPM3 protein protein. 88 4e-17
AL590431-4|CAH71262.1| 158|Homo sapiens tropomyosin 3 protein. 88 4e-17
AL590431-3|CAH71261.1| 158|Homo sapiens tropomyosin 3 protein. 88 4e-17
BX537964-1|CAD97928.1| 898|Homo sapiens hypothetical protein pr... 66 1e-10
BC105632-1|AAI05633.1| 898|Homo sapiens chromosome 10 open read... 66 1e-10
BC103499-1|AAI03500.1| 898|Homo sapiens chromosome 10 open read... 66 1e-10
BC100670-1|AAI00671.1| 1004|Homo sapiens C10orf118 protein protein. 66 1e-10
AK092712-1|BAC03956.1| 183|Homo sapiens protein ( Homo sapiens ... 66 1e-10
AF273054-1|AAM44457.1| 613|Homo sapiens CTCL tumor antigen HD-C... 66 1e-10
S73840-1|AAC13916.1| 231|Homo sapiens type IIA myosin heavy cha... 62 2e-09
BC126409-1|AAI26410.1| 1941|Homo sapiens myosin, heavy chain 2, ... 62 2e-09
AF111784-1|AAD29950.1| 1941|Homo sapiens myosin heavy chain IIa ... 62 2e-09
M12126-1|AAA61229.1| 131|Homo sapiens TPM2 protein. 62 2e-09
X03740-1|CAA27380.1| 876|Homo sapiens protein ( Human skeletal ... 62 3e-09
Z38133-1|CAA86293.1| 1937|Homo sapiens Myosin protein. 61 3e-09
X51592-1|CAA35941.1| 1437|Homo sapiens fetal-myosin heavy chain ... 61 3e-09
M12127-1|AAA36774.1| 131|Homo sapiens protein ( Human cytoskele... 61 3e-09
BC114545-1|AAI14546.1| 1939|Homo sapiens myosin, heavy chain 1, ... 61 3e-09
AK097432-1|BAC05050.1| 466|Homo sapiens protein ( Homo sapiens ... 61 3e-09
AF111785-1|AAD29951.1| 1939|Homo sapiens myosin heavy chain IIx/... 61 3e-09
X13939-1|CAA32122.1| 328|Homo sapiens laminin B2 protein. 60 6e-09
M55210-1|AAA59492.1| 1609|Homo sapiens laminin B2 chain protein. 60 6e-09
M36769-1|AAC17185.1| 1937|Homo sapiens perinatal myosin heavy ch... 60 6e-09
M27654-1|AAA59489.1| 217|Homo sapiens laminin B2 protein. 60 6e-09
J03202-1|AAA59488.1| 1609|Homo sapiens LAMB2 protein. 60 6e-09
AL450304-5|CAI14877.1| 1609|Homo sapiens laminin, gamma 1 (forme... 60 6e-09
AL354953-3|CAH70981.1| 1609|Homo sapiens laminin, gamma 1 (forme... 60 6e-09
AF111783-1|AAD29949.1| 1939|Homo sapiens myosin heavy chain IIb ... 60 8e-09
BC118982-1|AAI18983.1| 553|Homo sapiens KIAA2012 protein protein. 59 2e-08
AB095932-1|BAC23108.1| 555|Homo sapiens KIAA2012 protein protein. 59 2e-08
Z97054-3|CAI42646.1| 1233|Homo sapiens structural maintenance of... 58 2e-08
X51593-1|CAA35942.1| 1085|Homo sapiens embryonic myosin heavy ch... 58 2e-08
X15696-1|CAA33731.1| 1085|Homo sapiens protein ( Human muscle mR... 58 2e-08
X13988-1|CAA32167.1| 1940|Homo sapiens protein ( Human mRNA for ... 58 2e-08
X13100-1|CAA31492.1| 1167|Homo sapiens myosin heavy chain (1167 ... 58 2e-08
S78271-1|AAB34405.1| 1233|Homo sapiens SB1.8/DXS423E protein. 58 2e-08
D80000-1|BAA11495.2| 1233|Homo sapiens KIAA0178 protein. 58 2e-08
BC127816-1|AAI27817.1| 416|Homo sapiens Unknown (protein for IM... 58 2e-08
BC112127-1|AAI12128.1| 1233|Homo sapiens SMC1 structural mainten... 58 2e-08
BC064368-1|AAH64368.1| 847|Homo sapiens SMC1A protein protein. 58 2e-08
AY517555-1|AAT44528.1| 941|Homo sapiens hypothetical rhabdomyos... 58 2e-08
AL161779-1|CAI42089.1| 1233|Homo sapiens structural maintenance ... 58 2e-08
AK097517-1|BAC05084.1| 621|Homo sapiens protein ( Homo sapiens ... 58 2e-08
BC129821-1|AAI29822.1| 315|Homo sapiens FLJ36144 protein protein. 58 3e-08
AF111782-1|AAD29948.1| 1938|Homo sapiens myosin heavy chain prot... 58 3e-08
U30872-1|AAA82935.1| 3113|Homo sapiens mitosin protein. 58 4e-08
U19769-1|AAA82889.1| 3210|Homo sapiens CENP-F kinetochore protei... 58 4e-08
AL445666-1|CAH71810.1| 3114|Homo sapiens centromere protein F, 3... 58 4e-08
AL445305-6|CAH73032.1| 3114|Homo sapiens centromere protein F, 3... 58 4e-08
D00943-1|BAA00791.1| 1939|Homo sapiens cardiac alpha-myosin heav... 57 6e-08
Z29064-1|CAA82305.1| 896|Homo sapiens AF-1p protein. 57 7e-08
Z20656-1|CAA79675.1| 1939|Homo sapiens cardiac alpha-myosin heav... 57 7e-08
U07707-1|AAA52101.1| 896|Homo sapiens epidermal growth factor r... 57 7e-08
DQ367924-1|ABD34786.1| 896|Homo sapiens epidermal growth factor... 57 7e-08
BC132667-1|AAI32668.1| 1939|Homo sapiens myosin, heavy chain 6, ... 57 7e-08
AL671986-11|CAI13030.1| 896|Homo sapiens epidermal growth facto... 57 7e-08
AK093463-1|BAC04173.1| 650|Homo sapiens protein ( Homo sapiens ... 57 7e-08
BC112391-1|AAI12392.1| 957|Homo sapiens ELKS/RAB6-interacting/C... 56 1e-07
BC111550-1|AAI11551.1| 957|Homo sapiens ERC2 protein protein. 56 1e-07
AK092490-1|BAC03904.1| 280|Homo sapiens protein ( Homo sapiens ... 56 1e-07
AB002376-1|BAA20832.2| 970|Homo sapiens KIAA0378 protein. 56 1e-07
AF362887-1|AAK51964.1| 142|Homo sapiens tropomyosin 4-anaplasti... 56 1e-07
AF200415-1|AAF08305.2| 1825|Homo sapiens proliferation-related p... 56 1e-07
Z15005-1|CAA78727.1| 2663|Homo sapiens CENP-E protein. 55 2e-07
X69292-1|CAA49154.1| 881|Homo sapiens smooth muscle mysosin he... 55 2e-07
AB209996-1|BAE06078.1| 2585|Homo sapiens CENPE variant protein p... 55 2e-07
X82834-1|CAA58041.1| 2185|Homo sapiens 256 kD golgin protein. 55 3e-07
U41740-1|AAC50434.1| 2230|Homo sapiens trans-Golgi p230 protein. 55 3e-07
U31906-1|AAC51791.1| 2083|Homo sapiens golgin-245 protein. 55 3e-07
BC101520-1|AAI01521.1| 1194|Homo sapiens protein tyrosine phosph... 55 3e-07
BC101518-1|AAI01519.1| 1194|Homo sapiens protein tyrosine phosph... 55 3e-07
AB014554-1|BAA31629.2| 1267|Homo sapiens KIAA0654 protein protein. 55 3e-07
X03741-1|CAA27381.1| 635|Homo sapiens protein ( Human cardiac m... 54 4e-07
U80458-1|AAD00355.1| 1604|Homo sapiens microtubule associated pr... 54 4e-07
D10667-1|BAA36971.1| 1052|Homo sapiens smooth muscle myosin heav... 54 4e-07
BC104906-1|AAI04907.1| 1938|Homo sapiens myosin, heavy chain 11,... 54 4e-07
BC101677-1|AAI01678.1| 1938|Homo sapiens myosin, heavy chain 11,... 54 4e-07
BC080545-1|AAH80545.1| 498|Homo sapiens MYH11 protein protein. 54 4e-07
AY520817-1|AAS98911.1| 1945|Homo sapiens smooth muscle myosin he... 54 4e-07
AY520816-1|AAS98910.1| 1979|Homo sapiens smooth muscle myosin he... 54 4e-07
AF020091-1|AAB69327.1| 622|Homo sapiens smooth muscle myosin he... 54 4e-07
AF013570-1|AAB69326.1| 588|Homo sapiens smooth muscle myosin he... 54 4e-07
AF001548-1|AAC31665.1| 1857|Homo sapiens Myosin heavy chain (MHY... 54 4e-07
AB020673-1|BAA74889.2| 1984|Homo sapiens KIAA0866 protein protein. 54 4e-07
Z82215-4|CAB05105.1| 1960|Homo sapiens myosin, heavy chain 9, no... 54 5e-07
X52889-1|CAA37068.1| 1934|Homo sapiens cardiac beta myosin heavy... 54 5e-07
X51591-1|CAA35940.1| 1151|Homo sapiens beta-myosin heavy chain (... 54 5e-07
X06976-1|CAA30039.1| 543|Homo sapiens beta myosin heavy chain (... 54 5e-07
M58018-1|AAA62830.1| 1935|Homo sapiens beta-myosin heavy chain p... 54 5e-07
M57965-1|AAA51837.1| 1935|Homo sapiens beta-myosin heavy chain p... 54 5e-07
M25139-1|AAA60385.1| 611|Homo sapiens myosin heavy chain beta-s... 54 5e-07
M17712-1|AAA36343.1| 543|Homo sapiens protein ( Human cardiac m... 54 5e-07
EF560725-1|ABQ59035.1| 1934|Homo sapiens MYH7 protein protein. 54 5e-07
EF179180-1|ABN05283.1| 1935|Homo sapiens myosin, heavy chain 7, ... 54 5e-07
DQ139275-1|ABA43896.1| 1313|Homo sapiens Tax1-binding protein 2 ... 54 5e-07
CR456526-1|CAG30412.1| 1960|Homo sapiens MYH9 protein. 54 5e-07
BX284668-3|CAH70057.1| 1898|Homo sapiens ciliary rootlet coiled-... 54 5e-07
BX284668-2|CAH70055.1| 2017|Homo sapiens ciliary rootlet coiled-... 54 5e-07
BC142716-1|AAI42717.1| 601|Homo sapiens EPS15L1 protein protein. 54 5e-07
BC142662-1|AAI42663.1| 600|Homo sapiens EPS15L1 protein protein. 54 5e-07
BC131590-1|AAI31591.1| 754|Homo sapiens EPS15L1 protein protein. 54 5e-07
BC112173-1|AAI12174.1| 1935|Homo sapiens myosin, heavy chain 7, ... 54 5e-07
BC112171-1|AAI12172.1| 1935|Homo sapiens myosin, heavy chain 7, ... 54 5e-07
BC028423-1|AAH28423.1| 1022|Homo sapiens PMFBP1 protein protein. 54 5e-07
AY518538-1|AAT44534.1| 1179|Homo sapiens rhabdomyosarcoma antige... 54 5e-07
AL049569-4|CAI20365.1| 1898|Homo sapiens ciliary rootlet coiled-... 54 5e-07
AL049569-3|CAI20363.1| 2017|Homo sapiens ciliary rootlet coiled-... 54 5e-07
AK093285-1|BAC04121.1| 797|Homo sapiens protein ( Homo sapiens ... 54 5e-07
AJ238393-1|CAC20413.1| 1935|Homo sapiens beta-myosin heavy chain... 54 5e-07
AF110265-1|AAF21930.1| 864|Homo sapiens epidermal growth factor... 54 5e-07
AB209708-1|BAD92945.1| 1574|Homo sapiens myosin, heavy polypepti... 54 5e-07
AB191263-1|BAD52439.1| 1960|Homo sapiens non-muscle myosin heavy... 54 5e-07
AB015346-1|BAA88118.1| 864|Homo sapiens Eps15R protein. 54 5e-07
AB007914-1|BAA32290.2| 1919|Homo sapiens KIAA0445 protein protein. 54 5e-07
X97053-1|CAA65765.1| 566|Homo sapiens plectin protein. 54 7e-07
X64838-1|CAA46050.1| 1427|Homo sapiens restin protein. 54 7e-07
U63610-1|AAB05428.1| 4574|Homo sapiens plectin protein. 54 7e-07
U53204-1|AAB05427.1| 4574|Homo sapiens plectin protein. 54 7e-07
M97501-1|AAA35693.1| 1392|Homo sapiens cytoplasmic linker protei... 54 7e-07
BC126305-1|AAI26306.1| 1438|Homo sapiens CLIP1 protein protein. 54 7e-07
BC114213-1|AAI14214.1| 1392|Homo sapiens CAP-GLY domain containi... 54 7e-07
AY681966-1|AAV87216.1| 2069|Homo sapiens citron protein. 54 7e-07
AL832009-1|CAD89912.1| 1177|Homo sapiens hypothetical protein pr... 54 7e-07
U38292-1|AAB41133.1| 2805|Homo sapiens microtubule-associated pr... 53 9e-07
U38291-1|AAB41132.1| 2805|Homo sapiens microtubule-associated pr... 53 9e-07
U25725-1|AAA86889.1| 1017|Homo sapiens AH antigen protein. 53 9e-07
BC146779-1|AAI46780.1| 1669|Homo sapiens intersectin 2 protein. 53 9e-07
BC117209-1|AAI17210.1| 1438|Homo sapiens CLIP1 protein protein. 53 9e-07
BC091490-1|AAH91490.1| 620|Homo sapiens ODF2L protein protein. 53 9e-07
BC020921-1|AAH20921.1| 560|Homo sapiens ITSN2 protein protein. 53 9e-07
AY480051-1|AAR95684.1| 4547|Homo sapiens plectin 11 protein. 53 9e-07
AY480050-1|AAR95683.1| 4551|Homo sapiens plectin 10 protein. 53 9e-07
AY480049-1|AAR95682.1| 4547|Homo sapiens plectin 8 protein. 53 9e-07
AY480048-1|AAR95681.1| 4515|Homo sapiens plectin 7 protein. 53 9e-07
AY480047-1|AAR95680.1| 4684|Homo sapiens plectin 6 protein. 53 9e-07
AY480046-1|AAR95679.1| 4525|Homo sapiens plectin 3 protein. 53 9e-07
AY480045-1|AAR95678.1| 4533|Homo sapiens plectin 2 protein. 53 9e-07
AY480044-1|AAR95677.1| 4574|Homo sapiens plectin 1 protein. 53 9e-07
AK021545-1|BAB13841.1| 436|Homo sapiens protein ( Homo sapiens ... 53 9e-07
AF248540-1|AAF63600.1| 1681|Homo sapiens intersectin 2 protein. 53 9e-07
AF182199-1|AAF59904.1| 1248|Homo sapiens intersectin 2 short iso... 53 9e-07
AF182198-1|AAF59903.1| 1696|Homo sapiens intersectin 2 long isof... 53 9e-07
AC009228-1|AAX93122.1| 1329|Homo sapiens unknown protein. 53 9e-07
AB033082-1|BAA86570.1| 1676|Homo sapiens KIAA1256 protein protein. 53 9e-07
S67240-1|AAB28951.1| 330|Homo sapiens smooth muscle myosin heav... 53 1e-06
S67238-1|AAB28950.1| 296|Homo sapiens smooth muscle myosin heav... 53 1e-06
M21665-1|AAA36345.1| 524|Homo sapiens protein ( Human beta-myos... 53 1e-06
BC132736-1|AAI32737.1| 1843|Homo sapiens coiled-coil domain cont... 53 1e-06
AL121586-7|CAB89415.1| 2442|Homo sapiens centrosomal protein 250... 53 1e-06
AF049105-1|AAC07988.1| 2442|Homo sapiens centrosomal Nek2-associ... 53 1e-06
AF022655-1|AAC06349.1| 2442|Homo sapiens cep250 centrosome assoc... 53 1e-06
AB201172-1|BAE44387.1| 1870|Homo sapiens girdin protein. 53 1e-06
AB125644-1|BAF44475.1| 1843|Homo sapiens PKB/Akt-binding protein... 53 1e-06
BC146789-1|AAI46790.1| 1583|Homo sapiens GRIP and coiled-coil do... 52 2e-06
BC029425-1|AAH29425.1| 272|Homo sapiens Unknown (protein for IM... 52 2e-06
AL832639-1|CAD89954.1| 1331|Homo sapiens hypothetical protein pr... 52 2e-06
AL589649-3|CAH71820.1| 1213|Homo sapiens filamin A interacting p... 52 2e-06
AL589649-1|CAH71818.1| 1114|Homo sapiens filamin A interacting p... 52 2e-06
AL445465-2|CAH73615.1| 1213|Homo sapiens filamin A interacting p... 52 2e-06
AL445465-1|CAH73614.1| 1114|Homo sapiens filamin A interacting p... 52 2e-06
AK097021-1|BAC04928.1| 512|Homo sapiens protein ( Homo sapiens ... 52 2e-06
AK027705-1|BAB55310.1| 965|Homo sapiens protein ( Homo sapiens ... 52 2e-06
AB086011-1|BAC77067.1| 1213|Homo sapiens L-FILIP protein. 52 2e-06
AB033101-1|BAA86589.1| 1140|Homo sapiens KIAA1275 protein protein. 52 2e-06
AB002334-1|BAA20794.2| 1635|Homo sapiens KIAA0336 protein. 52 2e-06
BC132784-1|AAI32785.1| 1116|Homo sapiens ELKS/RAB6-interacting/C... 52 2e-06
BC132782-1|AAI32783.1| 1116|Homo sapiens ELKS/RAB6-interacting/C... 52 2e-06
AC012487-1|AAX88838.1| 1583|Homo sapiens unknown protein. 52 2e-06
AB053471-1|BAC54110.1| 1116|Homo sapiens ELKS epsilon protein. 52 2e-06
AB053470-1|BAC54109.1| 1088|Homo sapiens ELKS delta protein. 52 2e-06
Z75311-1|CAA99729.1| 1318|Homo sapiens RAD50 homologue hsRAD50 p... 52 3e-06
Z22664-1|CAA80377.1| 595|Homo sapiens membrane organizing prote... 52 3e-06
Y18000-2|CAA76993.1| 615|Homo sapiens NF2 protein protein. 52 3e-06
Y18000-1|CAA76992.1| 595|Homo sapiens NF2 protein protein. 52 3e-06
X72655-1|CAA51220.1| 595|Homo sapiens schwannomin protein. 52 3e-06
L11353-1|AAA36212.1| 595|Homo sapiens moesin-ezrin-radixin-like... 52 3e-06
CR456530-1|CAG30416.1| 595|Homo sapiens NF2 protein. 52 3e-06
BC020257-1|AAH20257.1| 595|Homo sapiens neurofibromin 2 (bilate... 52 3e-06
BC003112-1|AAH03112.2| 507|Homo sapiens neurofibromin 2 (bilate... 52 3e-06
AY257469-1|AAP13528.1| 2027|Homo sapiens rho/rac-interacting cit... 52 3e-06
AF369701-1|AAK54196.1| 590|Homo sapiens neurofibromatosis type ... 52 3e-06
AF369665-1|AAK54166.1| 507|Homo sapiens neurofibromatosis type ... 52 3e-06
AF369664-1|AAK54165.1| 549|Homo sapiens neurofibromatosis type ... 52 3e-06
AF369663-1|AAK54164.1| 548|Homo sapiens neurofibromatosis type ... 52 3e-06
AF369662-1|AAK54163.1| 590|Homo sapiens neurofibromatosis type ... 52 3e-06
AF369661-1|AAK54162.1| 595|Homo sapiens neurofibromatosis type ... 52 3e-06
AF369658-1|AAK54161.1| 590|Homo sapiens neurofibromatosis type ... 52 3e-06
AF369657-1|AAK54160.1| 595|Homo sapiens neurofibromatosis type ... 52 3e-06
AB209115-1|BAD92352.1| 1065|Homo sapiens restin isoform a varian... 52 3e-06
L02320-1|AAA36541.1| 583|Homo sapiens radixin protein. 51 4e-06
BC114620-1|AAI14621.1| 1756|Homo sapiens periplakin protein. 51 4e-06
BC078168-1|AAH78168.1| 887|Homo sapiens CCDC88A protein protein. 51 4e-06
BC013023-1|AAH13023.1| 1193|Homo sapiens NUMA1 protein protein. 51 4e-06
AL365436-3|CAI16590.1| 1203|Homo sapiens cingulin protein. 51 4e-06
AK131080-1|BAC85130.1| 563|Homo sapiens FLJ00279 protein protein. 51 4e-06
AF263462-1|AAF74498.1| 1203|Homo sapiens cingulin protein. 51 4e-06
AF041004-1|AAD17459.1| 1756|Homo sapiens periplakin protein. 51 4e-06
AF013717-1|AAC39668.1| 1756|Homo sapiens periplakin protein. 51 4e-06
AF001691-1|AAC17738.1| 1756|Homo sapiens 195 kDa cornified envel... 51 4e-06
AC002563-2|AAB71327.1| 1286|Homo sapiens WUGSC:H_127H14.1 protein. 51 4e-06
AB037740-1|BAA92557.1| 1208|Homo sapiens KIAA1319 protein protein. 51 4e-06
AB023166-1|BAA76793.2| 1559|Homo sapiens KIAA0949 protein protein. 51 4e-06
AB011140-1|BAA25494.1| 1426|Homo sapiens KIAA0568 protein protein. 51 4e-06
U22816-1|AAC50173.1| 1202|Homo sapiens LAR-interacting protein 1... 51 5e-06
U22815-1|AAC50172.1| 1185|Homo sapiens LAR-interacting protein 1... 51 5e-06
M21664-1|AAA36344.1| 532|Homo sapiens protein ( Human alpha-myo... 51 5e-06
BC034046-1|AAH34046.1| 1202|Homo sapiens protein tyrosine phosph... 51 5e-06
AY359522-1|AAQ57128.1| 657|Homo sapiens hypothetical protein DK... 51 5e-06
AL834265-1|CAD38940.1| 505|Homo sapiens hypothetical protein pr... 51 5e-06
AL445928-1|CAH72248.1| 657|Homo sapiens novel protein protein. 51 5e-06
AB033102-1|BAA86590.1| 1068|Homo sapiens KIAA1276 protein protein. 51 5e-06
Z11583-1|CAA77669.1| 2115|Homo sapiens NuMA protein protein. 50 7e-06
X78998-1|CAA55632.1| 1411|Homo sapiens endosomal protein protein. 50 7e-06
X75304-1|CAA53052.1| 3259|Homo sapiens giantin protein. 50 7e-06
D25542-1|BAA05025.1| 3225|Homo sapiens golgi antigen gcp372 prot... 50 7e-06
BC101026-1|AAI01027.1| 490|Homo sapiens SASS6 protein protein. 50 7e-06
BC009941-1|AAH09941.1| 550|Homo sapiens coiled-coil domain cont... 50 7e-06
BC008345-1|AAH08345.1| 963|Homo sapiens Unknown (protein for IM... 50 7e-06
BC008285-1|AAH08285.1| 550|Homo sapiens coiled-coil domain cont... 50 7e-06
BC004307-1|AAH04307.1| 273|Homo sapiens CCDC102A protein protein. 50 7e-06
AL832636-1|CAD89951.1| 546|Homo sapiens hypothetical protein pr... 50 7e-06
AF543495-1|AAN40505.1| 453|Homo sapiens melanoma-associated ant... 50 7e-06
AF432208-1|AAL99915.1| 187|Homo sapiens CLL-associated antigen ... 50 7e-06
AB210007-1|BAE06089.1| 2121|Homo sapiens NUMA1 variant protein p... 50 7e-06
AB208841-1|BAD92078.1| 1585|Homo sapiens Nuclear mitotic apparat... 50 7e-06
Z99496-1|CAI21605.1| 805|Homo sapiens chromosome 6 open reading... 50 9e-06
Z98946-1|CAB46379.1| 577|Homo sapiens moesin protein. 50 9e-06
M69066-1|AAA36322.1| 577|Homo sapiens moesin B protein. 50 9e-06
L40157-1|AAA79121.1| 1410|Homo sapiens endosome-associated prote... 50 9e-06
BC150248-1|AAI50249.1| 992|Homo sapiens ELKS/RAB6-interacting/C... 50 9e-06
BC017293-1|AAH17293.1| 577|Homo sapiens moesin protein. 50 9e-06
AL589993-1|CAI16048.1| 805|Homo sapiens chromosome 6 open readi... 50 9e-06
AL390069-1|CAI14134.1| 805|Homo sapiens chromosome 6 open readi... 50 9e-06
AF308284-1|AAG48252.1| 546|Homo sapiens serologically defined b... 50 9e-06
AB053468-1|BAC54107.1| 992|Homo sapiens ELKS beta protein. 50 9e-06
AB051536-1|BAB21840.2| 1047|Homo sapiens KIAA1749 protein protein. 50 9e-06
AB029004-1|BAA83033.2| 1003|Homo sapiens KIAA1081 protein protein. 50 9e-06
AB015617-1|BAA88763.1| 948|Homo sapiens ELKS protein. 50 9e-06
D87931-1|BAA75636.1| 1388|Homo sapiens Rho kinase protein. 50 1e-05
BC109126-1|AAI09127.1| 872|Homo sapiens chromosome 10 open read... 50 1e-05
BC047109-1|AAH47109.1| 583|Homo sapiens radixin protein. 50 1e-05
BC036225-1|AAH36225.1| 872|Homo sapiens chromosome 10 open read... 50 1e-05
AL355378-1|CAI15667.1| 872|Homo sapiens novel protein protein. 50 1e-05
AL162742-5|CAI12110.1| 872|Homo sapiens novel protein protein. 50 1e-05
AK093227-1|BAC04102.1| 550|Homo sapiens protein ( Homo sapiens ... 50 1e-05
AB014519-1|BAA31594.2| 1428|Homo sapiens KIAA0619 protein protein. 50 1e-05
X66397-1|CAA47021.1| 2349|Homo sapiens Tpr protein. 49 2e-05
U69668-1|AAB48030.1| 2363|Homo sapiens Tpr protein. 49 2e-05
U63139-1|AAB07119.1| 1312|Homo sapiens Rad50 protein. 49 2e-05
D86970-1|BAA13206.2| 2067|Homo sapiens KIAA0216 protein. 49 2e-05
BC146835-1|AAI46836.1| 716|Homo sapiens Unknown (protein for MG... 49 2e-05
BC103824-1|AAI03825.1| 546|Homo sapiens taxilin alpha protein. 49 2e-05
BC103823-1|AAI03824.1| 546|Homo sapiens taxilin alpha protein. 49 2e-05
BC089391-1|AAH89391.1| 466|Homo sapiens CCDC19 protein protein. 49 2e-05
BC080578-1|AAH80578.1| 546|Homo sapiens taxilin alpha protein. 49 2e-05
BC039612-1|AAH39612.1| 2002|Homo sapiens MYO18A protein protein. 49 2e-05
AY703984-1|AAV80770.1| 1581|Homo sapiens SP-A receptor subunit S... 49 2e-05
AY165122-1|AAO39147.1| 1995|Homo sapiens myosin heavy chain prot... 49 2e-05
AL596220-1|CAI13119.1| 2363|Homo sapiens translocated promoter r... 49 2e-05
AL590560-10|CAH71107.1| 551|Homo sapiens coiled-coil domain con... 49 2e-05
AL133553-3|CAI17859.1| 2363|Homo sapiens translocated promoter r... 49 2e-05
AL049795-2|CAI22055.1| 546|Homo sapiens novel protein protein. 49 2e-05
AF516206-1|AAO42465.1| 546|Homo sapiens taxilin protein. 49 2e-05
AF094758-1|AAD55817.1| 386|Homo sapiens nasopharyngeal epitheli... 49 2e-05
AF057300-1|AAD50326.1| 1173|Homo sapiens truncated RAD50 protein... 49 2e-05
AF057299-1|AAD50325.1| 1312|Homo sapiens RAD50-2 protein protein. 49 2e-05
AF034799-1|AAC26100.1| 1257|Homo sapiens liprin-alpha2 protein. 49 2e-05
AB177860-1|BAD66838.1| 1715|Homo sapiens KIAA0216 splice variant... 49 2e-05
AB177858-1|BAD66836.1| 2046|Homo sapiens KIAA0216 splice variant... 49 2e-05
AB111886-1|BAC98374.1| 1571|Homo sapiens KIAA2034 protein protein. 49 2e-05
AB046861-1|BAB13467.1| 718|Homo sapiens KIAA1641 protein protein. 49 2e-05
BC131515-1|AAI31516.1| 632|Homo sapiens GOLGA6 protein protein. 49 2e-05
BC118918-1|AAI18919.1| 1302|Homo sapiens cingulin-like 1 protein. 49 2e-05
BC112049-1|AAI12050.1| 1302|Homo sapiens cingulin-like 1 protein. 49 2e-05
BC093827-1|AAH93827.1| 1302|Homo sapiens cingulin-like 1 protein. 49 2e-05
BC046212-1|AAH46212.1| 364|Homo sapiens Similar to cytomatrix p... 49 2e-05
BC000280-1|AAH00280.1| 471|Homo sapiens MYH10 protein protein. 49 2e-05
AY282407-1|AAP40331.1| 1116|Homo sapiens M-phase phosphoprotein ... 49 2e-05
AY274808-1|AAP42073.1| 1302|Homo sapiens KIAA1749 protein protein. 49 2e-05
AL157400-6|CAI16830.1| 1820|Homo sapiens M-phase phosphoprotein ... 49 2e-05
AL157400-5|CAI16831.1| 1780|Homo sapiens M-phase phosphoprotein ... 49 2e-05
AL157389-3|CAI12886.1| 1820|Homo sapiens M-phase phosphoprotein ... 49 2e-05
AL157389-2|CAI12887.1| 1780|Homo sapiens M-phase phosphoprotein ... 49 2e-05
AL031283-6|CAI21428.1| 692|Homo sapiens forkhead-associated (FH... 49 2e-05
AK125925-1|BAC86346.1| 623|Homo sapiens protein ( Homo sapiens ... 49 2e-05
AK022532-1|BAB14081.1| 975|Homo sapiens protein ( Homo sapiens ... 49 2e-05
AF266285-1|AAF72535.1| 693|Homo sapiens golgin-like protein pro... 49 2e-05
AF263742-1|AAF72196.1| 693|Homo sapiens golgin-like protein pro... 49 2e-05
AB053469-1|BAC54108.1| 720|Homo sapiens ELKS gamma protein. 49 2e-05
AB033337-1|BAB69456.1| 1820|Homo sapiens mitotic kinesin-related... 49 2e-05
X58677-1|CAA41528.1| 608|Homo sapiens hemidesmosomal plaque pr... 48 3e-05
M63618-1|AAA35606.1| 2095|Homo sapiens bullous pemphigoid antige... 48 3e-05
L11690-1|AAA52288.1| 2649|Homo sapiens bullous pemphigoid antige... 48 3e-05
BC131805-1|AAI31806.1| 913|Homo sapiens CCDC46 protein protein. 48 3e-05
BC129803-1|AAI29804.1| 638|Homo sapiens MYH14 protein protein. 48 3e-05
BC104912-1|AAI04913.1| 1236|Homo sapiens PPFIA2 protein protein. 48 3e-05
AL096710-6|CAI22047.1| 2649|Homo sapiens dystonin protein. 48 3e-05
AK027863-1|BAB55415.1| 612|Homo sapiens protein ( Homo sapiens ... 48 3e-05
AF458591-1|AAM49719.1| 590|Homo sapiens hypothetical protein pr... 48 3e-05
AB210009-1|BAE06091.1| 1258|Homo sapiens PPFIA2 variant protein ... 48 3e-05
X03445-1|CAA27174.1| 572|Homo sapiens protein ( Human mRNA for ... 48 3e-05
X03444-1|CAA27173.1| 702|Homo sapiens protein ( Human mRNA for ... 48 3e-05
M69181-1|AAA99177.1| 1976|Homo sapiens non-muscle myosin B protein. 48 3e-05
M13452-1|AAA36160.1| 515|Homo sapiens protein ( Human lamin A m... 48 3e-05
M13451-1|AAA36164.1| 572|Homo sapiens protein ( Human lamin C m... 48 3e-05
BC117691-1|AAI17692.1| 1976|Homo sapiens myosin, heavy chain 10,... 48 3e-05
BC117690-1|AAI17691.1| 1976|Homo sapiens myosin, heavy chain 10,... 48 3e-05
BC113524-1|AAI13525.1| 578|Homo sapiens IFT74 protein protein. 48 3e-05
BC054492-1|AAH54492.1| 997|Homo sapiens RABGAP1 protein protein. 48 3e-05
BC041854-1|AAH41854.1| 274|Homo sapiens hypothetical protein LO... 48 3e-05
BC033088-1|AAH33088.1| 465|Homo sapiens LMNA protein protein. 48 3e-05
BC023634-1|AAH23634.2| 383|Homo sapiens IFT74 protein protein. 48 3e-05
BC014507-1|AAH14507.1| 664|Homo sapiens lamin A/C protein. 48 3e-05
BC003162-1|AAH03162.1| 572|Homo sapiens lamin A/C protein. 48 3e-05
BC000616-1|AAH00616.1| 585|Homo sapiens SWAP-70 protein protein. 48 3e-05
BC000511-1|AAH00511.1| 572|Homo sapiens lamin A/C protein. 48 3e-05
AY847597-1|AAW32540.1| 664|Homo sapiens lamin A/C transcript va... 48 3e-05
AY847596-1|AAW32539.1| 480|Homo sapiens lamin A/C transcript va... 48 3e-05
AY528714-1|ABB04050.1| 487|Homo sapiens rhabdomyosarcoma antige... 48 3e-05
AY357727-1|AAR29466.1| 614|Homo sapiens progerin protein. 48 3e-05
AY040325-1|AAK77221.1| 600|Homo sapiens capillary morphogenesis... 48 3e-05
AL589986-1|CAH70024.1| 1943|Homo sapiens trichohyalin protein. 48 3e-05
AL365338-3|CAH70298.1| 997|Homo sapiens RAB GTPase activating p... 48 3e-05
AL356133-4|CAH72643.1| 600|Homo sapiens intraflagellar transpor... 48 3e-05
AL139421-1|CAI22508.1| 1454|Homo sapiens coiled-coil domain cont... 48 3e-05
AL135927-8|CAI15527.1| 491|Homo sapiens lamin A/C protein. 48 3e-05
AL135927-7|CAI15526.1| 513|Homo sapiens lamin A/C protein. 48 3e-05
AL135927-4|CAI15522.1| 664|Homo sapiens lamin A/C protein. 48 3e-05
AL135927-3|CAI15523.1| 614|Homo sapiens lamin A/C protein. 48 3e-05
AL135927-2|CAI15521.1| 572|Homo sapiens lamin A/C protein. 48 3e-05
AL135927-1|CAI15520.1| 465|Homo sapiens lamin A/C protein. 48 3e-05
AL050195-1|CAB43313.1| 246|Homo sapiens hypothetical protein pr... 48 3e-05
AK024959-1|BAB15043.1| 696|Homo sapiens protein ( Homo sapiens ... 48 3e-05
AK023707-1|BAB14650.1| 435|Homo sapiens protein ( Homo sapiens ... 48 3e-05
AJ011679-1|CAB40267.2| 997|Homo sapiens Rab6 GTPase activating ... 48 3e-05
AF210818-1|AAF24486.1| 585|Homo sapiens SWAP-70 protein. 48 3e-05
AF134894-1|AAF61403.1| 585|Homo sapiens SWAP-70 homolog protein. 48 3e-05
AB210026-1|BAE06108.1| 2018|Homo sapiens MYH10 variant protein p... 48 3e-05
AB067524-1|BAB67830.1| 704|Homo sapiens KIAA1937 protein protein. 48 3e-05
AB014540-1|BAA31615.1| 603|Homo sapiens KIAA0640 protein protein. 48 3e-05
Z22551-1|CAA80271.1| 1356|Homo sapiens 156 kDa Protein protein. 48 5e-05
S67247-1|AAB28952.1| 226|Homo sapiens smooth muscle myosin heav... 48 5e-05
L25616-1|AAB65853.1| 1300|Homo sapiens kinectin protein. 48 5e-05
D13629-1|BAA02794.2| 1307|Homo sapiens KIAA0004 protein. 48 5e-05
BC130385-1|AAI30386.1| 1197|Homo sapiens structural maintenance ... 48 5e-05
BC117132-1|AAI17133.1| 1306|Homo sapiens kinectin 1 (kinesin rec... 48 5e-05
BC112337-1|AAI12338.1| 1306|Homo sapiens kinectin 1 (kinesin rec... 48 5e-05
BC098576-1|AAH98576.1| 918|Homo sapiens inner centromere protei... 48 5e-05
BC050555-1|AAH50555.1| 873|Homo sapiens KTN1 protein protein. 48 5e-05
BC032435-1|AAH32435.1| 716|Homo sapiens RABEP1 protein protein. 48 5e-05
AY847595-1|AAW32538.1| 664|Homo sapiens lamin A/C transcript va... 48 5e-05
AY714053-1|AAU04398.1| 918|Homo sapiens inner centromere protei... 48 5e-05
AY536375-1|AAT66048.1| 820|Homo sapiens rhabdomyosarcoma antige... 48 5e-05
AY264265-1|AAP20418.1| 1357|Homo sapiens kinectin variant 1 prot... 48 5e-05
AL354938-1|CAI16923.1| 1197|Homo sapiens structural maintenance ... 48 5e-05
AL161791-1|CAI16866.1| 1197|Homo sapiens structural maintenance ... 48 5e-05
AF092563-1|AAC72360.1| 1197|Homo sapiens chromosome-associated p... 48 5e-05
BC092419-1|AAH92419.1| 701|Homo sapiens hypothetical LOC550631 ... 47 6e-05
AF461266-1|AAL67520.1| 606|Homo sapiens RUFY2 protein. 47 6e-05
AF411980-1|AAL04164.1| 590|Homo sapiens Run- and FYVE-domain co... 47 6e-05
AF369700-1|AAK54195.1| 279|Homo sapiens neurofibromatosis type ... 47 6e-05
AF265230-1|AAK58539.1| 975|Homo sapiens RING finger protein 20 ... 47 6e-05
AB040970-1|BAA96061.1| 619|Homo sapiens KIAA1537 protein protein. 47 6e-05
AB023217-1|BAA76844.2| 1956|Homo sapiens KIAA1000 protein protein. 47 6e-05
Z98882-1|CAI95591.1| 756|Homo sapiens RAB11 family interacting ... 47 8e-05
M31013-1|AAA36349.1| 1247|Homo sapiens protein ( Human nonmuscle... 47 8e-05
BC151242-1|AAI51243.1| 1983|Homo sapiens myosin, heavy chain 7B,... 47 8e-05
BC113409-1|AAI13410.1| 1416|Homo sapiens uveal autoantigen with ... 47 8e-05
BC113407-1|AAI13408.1| 1416|Homo sapiens uveal autoantigen with ... 47 8e-05
BC110585-1|AAI10586.1| 975|Homo sapiens ring finger protein 20 ... 47 8e-05
BC110584-1|AAI10585.1| 975|Homo sapiens ring finger protein 20 ... 47 8e-05
BC051360-1|AAH51360.1| 756|Homo sapiens RAB11 family interactin... 47 8e-05
BC041700-1|AAH41700.1| 862|Homo sapiens RABEP1 protein protein. 47 8e-05
AY610514-1|AAT37906.1| 1302|Homo sapiens paracingulin protein. 47 8e-05
AY014284-1|AAK27309.1| 699|Homo sapiens nucleoporin NYD-SP7 pro... 47 8e-05
AL834464-1|CAD39123.1| 236|Homo sapiens hypothetical protein pr... 47 8e-05
AL591377-3|CAH69963.1| 977|Homo sapiens ring finger protein 20 ... 47 8e-05
AL451082-2|CAH72276.1| 1194|Homo sapiens protein tyrosine phosph... 47 8e-05
AL353621-9|CAI14618.1| 977|Homo sapiens ring finger protein 20 ... 47 8e-05
AL137068-7|CAD20123.1| 1007|Homo sapiens centrosomal protein 110... 47 8e-05
AL137068-5|CAI12358.1| 1773|Homo sapiens centrosomal protein 110... 47 8e-05
AL137068-2|CAM13285.1| 2325|Homo sapiens centrosomal protein 110... 47 8e-05
AL133324-2|CAI19310.2| 1983|Homo sapiens myosin, heavy chain 7B,... 47 8e-05
AL132825-6|CAI43047.2| 1983|Homo sapiens myosin, heavy chain 7B,... 47 8e-05
AL049542-2|CAI95788.1| 756|Homo sapiens RAB11 family interactin... 47 8e-05
AL023881-6|CAI95593.1| 756|Homo sapiens RAB11 family interactin... 47 8e-05
AK131470-1|BAD18615.1| 458|Homo sapiens protein ( Homo sapiens ... 47 8e-05
AK074079-1|BAB84905.1| 1793|Homo sapiens FLJ00150 protein protein. 47 8e-05
AK022300-1|BAB14005.1| 746|Homo sapiens protein ( Homo sapiens ... 47 8e-05
AF513978-1|AAP43846.1| 2325|Homo sapiens CENTRIOLIN protein. 47 8e-05
AF395731-1|AAL12940.1| 756|Homo sapiens eferin protein. 47 8e-05
AF322916-1|AAG49577.1| 1416|Homo sapiens uveal autoantigen protein. 47 8e-05
AF083322-1|AAC32373.1| 994|Homo sapiens centriole associated pr... 47 8e-05
AE006463-12|AAK61232.1| 756|Homo sapiens unknown function protein. 47 8e-05
AB046781-1|BAB13387.2| 1416|Homo sapiens KIAA1561 protein protein. 47 8e-05
AB040945-1|BAA96036.2| 2010|Homo sapiens KIAA1512 protein protein. 47 8e-05
AB014565-1|BAA31640.2| 760|Homo sapiens KIAA0665 protein protein. 47 8e-05
DQ679757-1|ABG74698.1| 1215|Homo sapiens intersectin 1 short for... 46 1e-04
DQ679756-1|ABG74697.1| 1178|Homo sapiens intersectin 1 short for... 46 1e-04
DQ679755-1|ABG74696.1| 1149|Homo sapiens intersectin 1 short for... 46 1e-04
DQ679754-1|ABG74695.1| 1144|Homo sapiens intersectin 1 short for... 46 1e-04
DQ386455-1|ABD72328.1| 1020|Homo sapiens intersectin 1 short for... 46 1e-04
DQ355971-1|ABC67469.1| 1711|Homo sapiens CDC42 binding protein k... 46 1e-04
DQ340865-1|ABC69037.1| 1076|Homo sapiens intersectin 1 short for... 46 1e-04
BX538175-1|CAD98050.1| 627|Homo sapiens hypothetical protein pr... 46 1e-04
BC117560-1|AAI17561.1| 1144|Homo sapiens ITSN1 protein protein. 46 1e-04
BC116186-1|AAI16187.1| 1721|Homo sapiens intersectin 1 (SH3 doma... 46 1e-04
BC116185-1|AAI16186.1| 1716|Homo sapiens ITSN1 protein protein. 46 1e-04
BC086869-1|AAH86869.1| 954|Homo sapiens FLJ25770 protein protein. 46 1e-04
BC047871-1|AAH47871.1| 933|Homo sapiens CDC42BPB protein protein. 46 1e-04
BC021714-1|AAH21714.1| 876|Homo sapiens PTPRF interacting prote... 46 1e-04
BC012443-1|AAH12443.1| 717|Homo sapiens hook homolog 2 (Drosoph... 46 1e-04
AY642382-1|AAV34207.1| 1135|Homo sapiens GPBP-interacting protei... 46 1e-04
AL136382-1|CAI23513.1| 620|Homo sapiens novel protein protein. 46 1e-04
AJ417067-1|CAD01135.1| 1286|Homo sapiens RPGR-interacting protei... 46 1e-04
AJ417048-1|CAD01136.1| 1286|Homo sapiens RPGR-interacting protei... 46 1e-04
AF514869-1|AAQ08179.1| 1133|Homo sapiens GPBP-interacting protei... 46 1e-04
AF514868-1|AAQ08178.1| 1133|Homo sapiens GPBP-interacting protei... 46 1e-04
AF514867-1|AAQ08177.1| 1135|Homo sapiens GPBP-interacting protei... 46 1e-04
AF329092-1|AAN16206.1| 764|Homo sapiens GPBP-interacting protei... 46 1e-04
AF295356-1|AAK71522.1| 527|Homo sapiens moesin/anaplastic lymph... 46 1e-04
AF128625-1|AAD37506.1| 1711|Homo sapiens CDC42-binding protein k... 46 1e-04
AF114488-1|AAD29953.1| 1220|Homo sapiens intersectin short isofo... 46 1e-04
AF114487-1|AAD29952.1| 1721|Homo sapiens intersectin long isofor... 46 1e-04
AF064244-1|AAC78611.1| 1721|Homo sapiens intersectin long form p... 46 1e-04
AF064243-1|AAC78610.1| 1220|Homo sapiens intersectin short form ... 46 1e-04
AF034803-1|AAC26104.1| 783|Homo sapiens liprin-beta2 protein. 46 1e-04
AB032950-1|BAA86438.2| 1760|Homo sapiens KIAA1124 protein protein. 46 1e-04
X91141-1|CAA62580.1| 862|Homo sapiens rabaptin-5 protein. 46 1e-04
X04627-1|CAA28300.1| 258|Homo sapiens beta-myosin heavy chain p... 46 1e-04
L09190-1|AAA65582.1| 1898|Homo sapiens trichohyalin protein. 46 1e-04
AL832637-1|CAD89952.1| 546|Homo sapiens hypothetical protein pr... 46 1e-04
AL136382-2|CAI23514.1| 636|Homo sapiens novel protein protein. 46 1e-04
AF282265-1|AAF87584.1| 919|Homo sapiens inner centromere protei... 46 1e-04
AF098638-1|AAC70781.1| 829|Homo sapiens rabaptin-4 protein. 46 1e-04
AB033055-1|BAA86543.1| 696|Homo sapiens KIAA1229 protein protein. 46 1e-04
Z97832-4|CAI20190.1| 631|Homo sapiens differentially expressed ... 46 2e-04
Z11584-1|CAA77670.1| 2101|Homo sapiens NuMA protein protein. 46 2e-04
M81105-1|AAA59888.1| 1337|Homo sapiens cellular myosin heavy cha... 46 2e-04
BC130453-1|AAI30454.1| 1726|Homo sapiens ANKRD26 protein protein. 46 2e-04
BC068006-1|AAH68006.1| 627|Homo sapiens ERC1 protein protein. 46 2e-04
BC049849-1|AAH49849.1| 1374|Homo sapiens MYH9 protein protein. 46 2e-04
AY241694-1|AAO91767.1| 631|Homo sapiens IRF4-binding protein pr... 46 2e-04
AL162272-4|CAC19649.1| 1710|Homo sapiens novel protein protein. 46 2e-04
>X06825-1|CAA29971.1| 284|Homo sapiens protein ( Human mRNA for
skeletal beta-tropomyosin. ).
Length = 284
Score = 206 bits (503), Expect = 6e-53
Identities = 102/213 (47%), Positives = 153/213 (71%)
Frame = +2
Query: 86 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 265
MDAIKKKMQ +KL+K+NA+D+A+ E + A R +++ EE + LQKKL E+++
Sbjct: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
Query: 266 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 445
+++A + LE+ EK+ T EA+VA+LNR++Q +EE+L++++ER TA QKL EA+++A
Sbjct: 61 SESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 446 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 625
DE+ R KV+ENRA +DEE+M+ QLKEA+ +AED+D K +EV+RKL +E ELE +E
Sbjct: 121 DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE 180
Query: 626 DRVKSGDAKISXLEXELKVVGNSLKSLEVSEXK 724
+R + ++K LE ELK+V N+LKSLE K
Sbjct: 181 ERAEVAESKCGDLEEELKIVTNNLKSLEAQADK 213
Score = 68.9 bits (161), Expect = 2e-11
Identities = 48/209 (22%), Positives = 105/209 (50%)
Frame = +2
Query: 80 ATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLI 259
A + ++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + EE +
Sbjct: 83 ADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKME 142
Query: 260 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 439
L + +L++A E+ +++ EVA RK+ +E +LE+SEER+ A+ K + ++
Sbjct: 143 LQEMQLKEAKHIAEDSDRKYE----EVA---RKLVILEGELERSEERAEVAESKCGDLEE 195
Query: 440 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 619
K LE +A + + D+ ++K ++A+ +++ R +A +E ++
Sbjct: 196 ELKIVTNNLKSLEAQADKYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDD 255
Query: 620 AEDRVKSGDAKISXLEXELKVVGNSLKSL 706
ED V + K + EL N + SL
Sbjct: 256 LEDEVYAQKMKYKAISEELDNALNDITSL 284
>AL133410-4|CAI10977.1| 284|Homo sapiens tropomyosin 2 (beta)
protein.
Length = 284
Score = 206 bits (503), Expect = 6e-53
Identities = 102/213 (47%), Positives = 153/213 (71%)
Frame = +2
Query: 86 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 265
MDAIKKKMQ +KL+K+NA+D+A+ E + A R +++ EE + LQKKL E+++
Sbjct: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
Query: 266 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 445
+++A + LE+ EK+ T EA+VA+LNR++Q +EE+L++++ER TA QKL EA+++A
Sbjct: 61 SESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 446 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 625
DE+ R KV+ENRA +DEE+M+ QLKEA+ +AED+D K +EV+RKL +E ELE +E
Sbjct: 121 DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE 180
Query: 626 DRVKSGDAKISXLEXELKVVGNSLKSLEVSEXK 724
+R + ++K LE ELK+V N+LKSLE K
Sbjct: 181 ERAEVAESKCGDLEEELKIVTNNLKSLEAQADK 213
Score = 68.9 bits (161), Expect = 2e-11
Identities = 48/209 (22%), Positives = 105/209 (50%)
Frame = +2
Query: 80 ATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLI 259
A + ++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + EE +
Sbjct: 83 ADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKME 142
Query: 260 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 439
L + +L++A E+ +++ EVA RK+ +E +LE+SEER+ A+ K + ++
Sbjct: 143 LQEMQLKEAKHIAEDSDRKYE----EVA---RKLVILEGELERSEERAEVAESKCGDLEE 195
Query: 440 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 619
K LE +A + + D+ ++K ++A+ +++ R +A +E ++
Sbjct: 196 ELKIVTNNLKSLEAQADKYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDD 255
Query: 620 AEDRVKSGDAKISXLEXELKVVGNSLKSL 706
ED V + K + EL N + SL
Sbjct: 256 LEDEVYAQKMKYKAISEELDNALNDITSL 284
>AL133410-3|CAI10976.1| 322|Homo sapiens tropomyosin 2 (beta)
protein.
Length = 322
Score = 206 bits (503), Expect = 6e-53
Identities = 102/213 (47%), Positives = 153/213 (71%)
Frame = +2
Query: 86 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 265
MDAIKKKMQ +KL+K+NA+D+A+ E + A R +++ EE + LQKKL E+++
Sbjct: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
Query: 266 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 445
+++A + LE+ EK+ T EA+VA+LNR++Q +EE+L++++ER TA QKL EA+++A
Sbjct: 61 SESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 446 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 625
DE+ R KV+ENRA +DEE+M+ QLKEA+ +AED+D K +EV+RKL +E ELE +E
Sbjct: 121 DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE 180
Query: 626 DRVKSGDAKISXLEXELKVVGNSLKSLEVSEXK 724
+R + ++K LE ELK+V N+LKSLE K
Sbjct: 181 ERAEVAESKCGDLEEELKIVTNNLKSLEAQADK 213
>AL133410-1|CAI10975.1| 284|Homo sapiens tropomyosin 2 (beta)
protein.
Length = 284
Score = 206 bits (503), Expect = 6e-53
Identities = 102/213 (47%), Positives = 153/213 (71%)
Frame = +2
Query: 86 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 265
MDAIKKKMQ +KL+K+NA+D+A+ E + A R +++ EE + LQKKL E+++
Sbjct: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
Query: 266 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 445
+++A + LE+ EK+ T EA+VA+LNR++Q +EE+L++++ER TA QKL EA+++A
Sbjct: 61 SESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 446 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 625
DE+ R KV+ENRA +DEE+M+ QLKEA+ +AED+D K +EV+RKL +E ELE +E
Sbjct: 121 DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE 180
Query: 626 DRVKSGDAKISXLEXELKVVGNSLKSLEVSEXK 724
+R + ++K LE ELK+V N+LKSLE K
Sbjct: 181 ERAEVAESKCGDLEEELKIVTNNLKSLEAQADK 213
Score = 60.5 bits (140), Expect = 6e-09
Identities = 41/187 (21%), Positives = 97/187 (51%)
Frame = +2
Query: 80 ATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLI 259
A + ++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + EE +
Sbjct: 83 ADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKME 142
Query: 260 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 439
L + +L++A E+ +++ EVA RK+ +E +LE+SEER+ A+ K + ++
Sbjct: 143 LQEMQLKEAKHIAEDSDRKYE----EVA---RKLVILEGELERSEERAEVAESKCGDLEE 195
Query: 440 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 619
K LE +A + + D+ ++K ++A+ +++ R +A +E ++
Sbjct: 196 ELKIVTNNLKSLEAQADKYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDD 255
Query: 620 AEDRVKS 640
E+ + S
Sbjct: 256 LEETLAS 262
Score = 41.9 bits (94), Expect = 0.002
Identities = 39/161 (24%), Positives = 77/161 (47%), Gaps = 10/161 (6%)
Frame = +2
Query: 92 AIKKKMQAMKLEKDNAM---DKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 262
A + + MK+ ++ AM +K + E Q ++A AE + + E+ +KL +E +L
Sbjct: 119 AADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELER 178
Query: 263 NKNKLEQANK---DLEEKEKQLT----ATEAEVAALNRKVQQIEEDLEKSEERSGTAQQK 421
++ + E A DLEE+ K +T + EA+ + K + EE+++ EE+ A+ +
Sbjct: 179 SEERAEVAESKCGDLEEELKIVTNNLKSLEAQADKYSTKEDKYEEEIKLLEEKLKEAETR 238
Query: 422 LLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL 544
A++S + + LE +E ++ L + L
Sbjct: 239 AEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLL 279
>M19713-1|AAA61225.1| 284|Homo sapiens TPM1 protein.
Length = 284
Score = 204 bits (499), Expect = 2e-52
Identities = 104/213 (48%), Positives = 152/213 (71%)
Frame = +2
Query: 86 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 265
MDAIKKKMQ +KL+K+NA+D+A+ E + A R++++ +E+ LQKKL E++L
Sbjct: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
Query: 266 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 445
L+ A + LE EK+ T EA+VA+LNR++Q +EE+L++++ER TA QKL EA+++A
Sbjct: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 446 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 625
DE+ R KV+E+RAQ+DEE+M+ QLKEA+ +AEDAD K +EV+RKL +E +LE AE
Sbjct: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
Query: 626 DRVKSGDAKISXLEXELKVVGNSLKSLEVSEXK 724
+R + + K + LE ELK V N+LKSLE K
Sbjct: 181 ERAELSEGKCAELEEELKTVTNNLKSLEAQAEK 213
Score = 68.5 bits (160), Expect = 2e-11
Identities = 45/209 (21%), Positives = 106/209 (50%)
Frame = +2
Query: 80 ATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLI 259
A + ++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + EE +
Sbjct: 83 ADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKME 142
Query: 260 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 439
+ + +L++A E+ +++ EVA RK+ IE DLE++EER+ ++ K E ++
Sbjct: 143 IQEIQLKEAKHIAEDADRKYE----EVA---RKLVIIESDLERAEERAELSEGKCAELEE 195
Query: 440 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 619
K LE +A++ ++ D+ ++K ++A+ +++ R + +E ++
Sbjct: 196 ELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDD 255
Query: 620 AEDRVKSGDAKISXLEXELKVVGNSLKSL 706
ED + + K + EL N + S+
Sbjct: 256 LEDELYAQKLKYKAISEELDHALNDMTSI 284
>AY640415-1|AAT68295.1| 284|Homo sapiens tropomyosin alpha striated
muscle isoform protein.
Length = 284
Score = 204 bits (498), Expect = 3e-52
Identities = 104/213 (48%), Positives = 151/213 (70%)
Frame = +2
Query: 86 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 265
MDAIKKKMQ +KL+K+NA+D+A+ E + A R++++ +E+ LQKKL E++L
Sbjct: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
Query: 266 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 445
L+ A + LE EK+ T EA+VA+LNR++Q +EE+L++++ER TA QKL EA+++A
Sbjct: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 446 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 625
DE+ R KV+E+RAQ+DEE+M+ QLKEA+ +AEDAD K +EV+RKL +E +LE AE
Sbjct: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
Query: 626 DRVKSGDAKISXLEXELKVVGNSLKSLEVSEXK 724
+R + + K + LE ELK V N LKSLE K
Sbjct: 181 ERAELSEGKCAELEEELKTVTNDLKSLEAQAEK 213
Score = 68.1 bits (159), Expect = 3e-11
Identities = 45/209 (21%), Positives = 106/209 (50%)
Frame = +2
Query: 80 ATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLI 259
A + ++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + EE +
Sbjct: 83 ADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKME 142
Query: 260 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 439
+ + +L++A E+ +++ EVA RK+ IE DLE++EER+ ++ K E ++
Sbjct: 143 IQEIQLKEAKHIAEDADRKYE----EVA---RKLVIIESDLERAEERAELSEGKCAELEE 195
Query: 440 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 619
K LE +A++ ++ D+ ++K ++A+ +++ R + +E ++
Sbjct: 196 ELKTVTNDLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDD 255
Query: 620 AEDRVKSGDAKISXLEXELKVVGNSLKSL 706
ED + + K + EL N + S+
Sbjct: 256 LEDELYAQKLKYKAISEELDHALNDMTSI 284
>X04201-1|CAA27798.1| 285|Homo sapiens protein ( Human skeletal
muscle 1.3 kb mRNA for tropomyosin. ).
Length = 285
Score = 200 bits (488), Expect = 4e-51
Identities = 101/213 (47%), Positives = 151/213 (70%)
Frame = +2
Query: 86 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 265
M+AIKKKMQ +KL+K+NA+D+A+ E + + A R++++ +E+ +QKKL E++L
Sbjct: 2 MEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKY 61
Query: 266 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 445
L+ A + LE EK+ EAEVA+LNR++Q +EE+L++++ER TA QKL EA+++A
Sbjct: 62 SEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 121
Query: 446 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 625
DE+ R KV+ENRA +DEE+M+ QLKEA+ +AE+AD K +EV+RKL +E +LE E
Sbjct: 122 DESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTE 181
Query: 626 DRVKSGDAKISXLEXELKVVGNSLKSLEVSEXK 724
+R + ++K S LE ELK V N+LKSLE K
Sbjct: 182 ERAELAESKCSELEEELKNVTNNLKSLEAQAEK 214
Score = 72.5 bits (170), Expect = 1e-12
Identities = 49/209 (23%), Positives = 107/209 (51%)
Frame = +2
Query: 80 ATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLI 259
A + ++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + EE +
Sbjct: 84 AEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKME 143
Query: 260 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 439
L + +L++A EE +++ EVA RK+ IE DLE++EER+ A+ K E ++
Sbjct: 144 LQEIQLKEAKHIAEEADRKYE----EVA---RKLVIIEGDLERTEERAELAESKCSELEE 196
Query: 440 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 619
K LE +A++ ++ D+ ++K ++A+ +++ R +A +E ++
Sbjct: 197 ELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDD 256
Query: 620 AEDRVKSGDAKISXLEXELKVVGNSLKSL 706
ED + + K + EL N + S+
Sbjct: 257 LEDELYAQKLKYKAISEELDHALNDMTSI 285
>BC008425-1|AAH08425.1| 285|Homo sapiens tropomyosin 3 protein.
Length = 285
Score = 200 bits (488), Expect = 4e-51
Identities = 101/213 (47%), Positives = 151/213 (70%)
Frame = +2
Query: 86 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 265
M+AIKKKMQ +KL+K+NA+D+A+ E + + A R++++ +E+ +QKKL E++L
Sbjct: 2 MEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKY 61
Query: 266 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 445
L+ A + LE EK+ EAEVA+LNR++Q +EE+L++++ER TA QKL EA+++A
Sbjct: 62 SEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 121
Query: 446 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 625
DE+ R KV+ENRA +DEE+M+ QLKEA+ +AE+AD K +EV+RKL +E +LE E
Sbjct: 122 DESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTE 181
Query: 626 DRVKSGDAKISXLEXELKVVGNSLKSLEVSEXK 724
+R + ++K S LE ELK V N+LKSLE K
Sbjct: 182 ERAELAESKCSELEEELKNVTNNLKSLEAQAEK 214
Score = 72.5 bits (170), Expect = 1e-12
Identities = 49/209 (23%), Positives = 107/209 (51%)
Frame = +2
Query: 80 ATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLI 259
A + ++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + EE +
Sbjct: 84 AEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKME 143
Query: 260 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 439
L + +L++A EE +++ EVA RK+ IE DLE++EER+ A+ K E ++
Sbjct: 144 LQEIQLKEAKHIAEEADRKYE----EVA---RKLVIIEGDLERTEERAELAESKCSELEE 196
Query: 440 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 619
K LE +A++ ++ D+ ++K ++A+ +++ R +A +E ++
Sbjct: 197 ELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDD 256
Query: 620 AEDRVKSGDAKISXLEXELKVVGNSLKSL 706
ED + + K + EL N + S+
Sbjct: 257 LEDELYAQKLKYKAISEELDHALNDMTSI 285
>BC008407-1|AAH08407.1| 285|Homo sapiens tropomyosin 3 protein.
Length = 285
Score = 200 bits (488), Expect = 4e-51
Identities = 101/213 (47%), Positives = 151/213 (70%)
Frame = +2
Query: 86 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 265
M+AIKKKMQ +KL+K+NA+D+A+ E + + A R++++ +E+ +QKKL E++L
Sbjct: 2 MEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKY 61
Query: 266 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 445
L+ A + LE EK+ EAEVA+LNR++Q +EE+L++++ER TA QKL EA+++A
Sbjct: 62 SEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 121
Query: 446 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 625
DE+ R KV+ENRA +DEE+M+ QLKEA+ +AE+AD K +EV+RKL +E +LE E
Sbjct: 122 DESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTE 181
Query: 626 DRVKSGDAKISXLEXELKVVGNSLKSLEVSEXK 724
+R + ++K S LE ELK V N+LKSLE K
Sbjct: 182 ERAELAESKCSELEEELKNVTNNLKSLEAQAEK 214
Score = 72.5 bits (170), Expect = 1e-12
Identities = 49/209 (23%), Positives = 107/209 (51%)
Frame = +2
Query: 80 ATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLI 259
A + ++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + EE +
Sbjct: 84 AEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKME 143
Query: 260 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 439
L + +L++A EE +++ EVA RK+ IE DLE++EER+ A+ K E ++
Sbjct: 144 LQEIQLKEAKHIAEEADRKYE----EVA---RKLVIIEGDLERTEERAELAESKCSELEE 196
Query: 440 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 619
K LE +A++ ++ D+ ++K ++A+ +++ R +A +E ++
Sbjct: 197 ELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDD 256
Query: 620 AEDRVKSGDAKISXLEXELKVVGNSLKSL 706
ED + + K + EL N + S+
Sbjct: 257 LEDELYAQKLKYKAISEELDHALNDMTSI 285
>AL590431-12|CAH71269.1| 284|Homo sapiens tropomyosin 3 protein.
Length = 284
Score = 200 bits (488), Expect = 4e-51
Identities = 101/213 (47%), Positives = 151/213 (70%)
Frame = +2
Query: 86 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 265
M+AIKKKMQ +KL+K+NA+D+A+ E + + A R++++ +E+ +QKKL E++L
Sbjct: 1 MEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKY 60
Query: 266 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 445
L+ A + LE EK+ EAEVA+LNR++Q +EE+L++++ER TA QKL EA+++A
Sbjct: 61 SEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 446 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 625
DE+ R KV+ENRA +DEE+M+ QLKEA+ +AE+AD K +EV+RKL +E +LE E
Sbjct: 121 DESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTE 180
Query: 626 DRVKSGDAKISXLEXELKVVGNSLKSLEVSEXK 724
+R + ++K S LE ELK V N+LKSLE K
Sbjct: 181 ERAELAESKCSELEEELKNVTNNLKSLEAQAEK 213
Score = 72.5 bits (170), Expect = 1e-12
Identities = 49/209 (23%), Positives = 107/209 (51%)
Frame = +2
Query: 80 ATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLI 259
A + ++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + EE +
Sbjct: 83 AEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKME 142
Query: 260 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 439
L + +L++A EE +++ EVA RK+ IE DLE++EER+ A+ K E ++
Sbjct: 143 LQEIQLKEAKHIAEEADRKYE----EVA---RKLVIIEGDLERTEERAELAESKCSELEE 195
Query: 440 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 619
K LE +A++ ++ D+ ++K ++A+ +++ R +A +E ++
Sbjct: 196 ELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDD 255
Query: 620 AEDRVKSGDAKISXLEXELKVVGNSLKSL 706
ED + + K + EL N + S+
Sbjct: 256 LEDELYAQKLKYKAISEELDHALNDMTSI 284
>AK023385-1|BAB14554.1| 284|Homo sapiens protein ( Homo sapiens
cDNA FLJ13323 fis, clone OVARC1001731, highly similar to
TROPOMYOSIN ALPHA CHAIN, FIBROBLAST ISOFORM F2. ).
Length = 284
Score = 200 bits (487), Expect = 5e-51
Identities = 103/213 (48%), Positives = 149/213 (69%)
Frame = +2
Query: 86 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 265
M+AIKKKMQ +KL+K+NA+D+A+ E + A + ++V EE+ LQKKL E++L
Sbjct: 1 MEAIKKKMQMLKLDKENAIDRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDKY 60
Query: 266 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 445
L+ A + LE EK+ + E +VAALNR++Q +EE+L++++ER TA QKL EA+++A
Sbjct: 61 SEDLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 446 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 625
DE+ R KV+ENRA +DEE+M+ QLKEA+ +AE+AD K +EV+RKL +E ELE AE
Sbjct: 121 DESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAE 180
Query: 626 DRVKSGDAKISXLEXELKVVGNSLKSLEVSEXK 724
+R + + K LE ELK V N+LKSLE + K
Sbjct: 181 ERAEVSELKCGDLEEELKNVTNNLKSLEAASEK 213
>M75165-1|AAB59509.1| 284|Homo sapiens tropomyosin protein.
Length = 284
Score = 198 bits (484), Expect = 1e-50
Identities = 98/211 (46%), Positives = 151/211 (71%)
Frame = +2
Query: 86 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 265
MDAIKKKMQ +KL+K+NA+D+A+ E + A R +++ EE + LQKKL E+++
Sbjct: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
Query: 266 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 445
+++A + LE+ EK+ T EA+VA+LNR++Q +EE+L++++ER TA QKL EA+++A
Sbjct: 61 SESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 446 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 625
DE+ R KV+ENRA +DEE+M+ QLKEA+ +AED+D K +EV+RKL +E ELE +E
Sbjct: 121 DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE 180
Query: 626 DRVKSGDAKISXLEXELKVVGNSLKSLEVSE 718
+R + +++ LE EL+ + +LKSL SE
Sbjct: 181 ERAEVAESRARQLEEELRTMDQALKSLMASE 211
Score = 58.8 bits (136), Expect = 2e-08
Identities = 45/190 (23%), Positives = 101/190 (53%), Gaps = 3/190 (1%)
Frame = +2
Query: 80 ATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLI 259
A + ++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + EE +
Sbjct: 83 ADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKME 142
Query: 260 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 439
L + +L++A E+ +++ EVA RK+ +E +LE+SEER+ A+ + A+Q
Sbjct: 143 LQEMQLKEAKHIAEDSDRKYE----EVA---RKLVILEGELERSEERAEVAESR---ARQ 192
Query: 440 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAE---DADGKSDEVSRKLAFVEDE 610
+E M + L++ +EE + +E +LL E +A+ +++ R +A +E
Sbjct: 193 LEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKT 252
Query: 611 LEVAEDRVKS 640
++ E+ + S
Sbjct: 253 IDDLEETLAS 262
Score = 37.1 bits (82), Expect = 0.065
Identities = 34/161 (21%), Positives = 74/161 (45%), Gaps = 10/161 (6%)
Frame = +2
Query: 92 AIKKKMQAMKLEKDNAM---DKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 262
A + + MK+ ++ AM +K + E Q ++A AE + + E+ +KL +E +L
Sbjct: 119 AADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELER 178
Query: 263 NKNKLEQANKDLEEKEKQLTATEAEVAAL-------NRKVQQIEEDLEKSEERSGTAQQK 421
++ + E A + E++L + + +L + K + EE+++ EE+ A+ +
Sbjct: 179 SEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETR 238
Query: 422 LLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL 544
A++S + + LE +E ++ L + L
Sbjct: 239 AEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLL 279
>M74817-1|AAA61230.1| 284|Homo sapiens tropomyosin-1 protein.
Length = 284
Score = 198 bits (484), Expect = 1e-50
Identities = 98/211 (46%), Positives = 151/211 (71%)
Frame = +2
Query: 86 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 265
MDAIKKKMQ +KL+K+NA+D+A+ E + A R +++ EE + LQKKL E+++
Sbjct: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
Query: 266 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 445
+++A + LE+ EK+ T EA+VA+LNR++Q +EE+L++++ER TA QKL EA+++A
Sbjct: 61 SESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 446 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 625
DE+ R KV+ENRA +DEE+M+ QLKEA+ +AED+D K +EV+RKL +E ELE +E
Sbjct: 121 DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE 180
Query: 626 DRVKSGDAKISXLEXELKVVGNSLKSLEVSE 718
+R + +++ LE EL+ + +LKSL SE
Sbjct: 181 ERAEVAESRARQLEEELRTMDQALKSLMASE 211
Score = 58.8 bits (136), Expect = 2e-08
Identities = 45/190 (23%), Positives = 101/190 (53%), Gaps = 3/190 (1%)
Frame = +2
Query: 80 ATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLI 259
A + ++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + EE +
Sbjct: 83 ADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKME 142
Query: 260 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 439
L + +L++A E+ +++ EVA RK+ +E +LE+SEER+ A+ + A+Q
Sbjct: 143 LQEMQLKEAKHIAEDSDRKYE----EVA---RKLVILEGELERSEERAEVAESR---ARQ 192
Query: 440 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAE---DADGKSDEVSRKLAFVEDE 610
+E M + L++ +EE + +E +LL E +A+ +++ R +A +E
Sbjct: 193 LEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKT 252
Query: 611 LEVAEDRVKS 640
++ E+ + S
Sbjct: 253 IDDLEETLAS 262
Score = 37.1 bits (82), Expect = 0.065
Identities = 34/161 (21%), Positives = 74/161 (45%), Gaps = 10/161 (6%)
Frame = +2
Query: 92 AIKKKMQAMKLEKDNAM---DKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 262
A + + MK+ ++ AM +K + E Q ++A AE + + E+ +KL +E +L
Sbjct: 119 AADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELER 178
Query: 263 NKNKLEQANKDLEEKEKQLTATEAEVAAL-------NRKVQQIEEDLEKSEERSGTAQQK 421
++ + E A + E++L + + +L + K + EE+++ EE+ A+ +
Sbjct: 179 SEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETR 238
Query: 422 LLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL 544
A++S + + LE +E ++ L + L
Sbjct: 239 AEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLL 279
>M12125-1|AAA36773.1| 284|Homo sapiens protein ( Human fibroblast
muscle-type tropomyosin mRNA, complete cds. ).
Length = 284
Score = 198 bits (484), Expect = 1e-50
Identities = 98/211 (46%), Positives = 151/211 (71%)
Frame = +2
Query: 86 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 265
MDAIKKKMQ +KL+K+NA+D+A+ E + A R +++ EE + LQKKL E+++
Sbjct: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
Query: 266 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 445
+++A + LE+ EK+ T EA+VA+LNR++Q +EE+L++++ER TA QKL EA+++A
Sbjct: 61 SESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 446 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 625
DE+ R KV+ENRA +DEE+M+ QLKEA+ +AED+D K +EV+RKL +E ELE +E
Sbjct: 121 DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE 180
Query: 626 DRVKSGDAKISXLEXELKVVGNSLKSLEVSE 718
+R + +++ LE EL+ + +LKSL SE
Sbjct: 181 ERAEVAESRARQLEEELRTMDQALKSLMASE 211
Score = 58.8 bits (136), Expect = 2e-08
Identities = 45/190 (23%), Positives = 101/190 (53%), Gaps = 3/190 (1%)
Frame = +2
Query: 80 ATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLI 259
A + ++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + EE +
Sbjct: 83 ADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKME 142
Query: 260 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 439
L + +L++A E+ +++ EVA RK+ +E +LE+SEER+ A+ + A+Q
Sbjct: 143 LQEMQLKEAKHIAEDSDRKYE----EVA---RKLVILEGELERSEERAEVAESR---ARQ 192
Query: 440 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAE---DADGKSDEVSRKLAFVEDE 610
+E M + L++ +EE + +E +LL E +A+ +++ R +A +E
Sbjct: 193 LEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKT 252
Query: 611 LEVAEDRVKS 640
++ E+ + S
Sbjct: 253 IDDLEETLAS 262
Score = 37.1 bits (82), Expect = 0.065
Identities = 34/161 (21%), Positives = 74/161 (45%), Gaps = 10/161 (6%)
Frame = +2
Query: 92 AIKKKMQAMKLEKDNAM---DKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 262
A + + MK+ ++ AM +K + E Q ++A AE + + E+ +KL +E +L
Sbjct: 119 AADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELER 178
Query: 263 NKNKLEQANKDLEEKEKQLTATEAEVAAL-------NRKVQQIEEDLEKSEERSGTAQQK 421
++ + E A + E++L + + +L + K + EE+++ EE+ A+ +
Sbjct: 179 SEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETR 238
Query: 422 LLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL 544
A++S + + LE +E ++ L + L
Sbjct: 239 AEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLL 279
>BC011776-1|AAH11776.1| 284|Homo sapiens tropomyosin 2 (beta)
protein.
Length = 284
Score = 198 bits (484), Expect = 1e-50
Identities = 98/211 (46%), Positives = 151/211 (71%)
Frame = +2
Query: 86 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 265
MDAIKKKMQ +KL+K+NA+D+A+ E + A R +++ EE + LQKKL E+++
Sbjct: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
Query: 266 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 445
+++A + LE+ EK+ T EA+VA+LNR++Q +EE+L++++ER TA QKL EA+++A
Sbjct: 61 SESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 446 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 625
DE+ R KV+ENRA +DEE+M+ QLKEA+ +AED+D K +EV+RKL +E ELE +E
Sbjct: 121 DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE 180
Query: 626 DRVKSGDAKISXLEXELKVVGNSLKSLEVSE 718
+R + +++ LE EL+ + +LKSL SE
Sbjct: 181 ERAEVAESRARQLEEELRTMDQALKSLMASE 211
Score = 58.8 bits (136), Expect = 2e-08
Identities = 45/190 (23%), Positives = 101/190 (53%), Gaps = 3/190 (1%)
Frame = +2
Query: 80 ATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLI 259
A + ++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + EE +
Sbjct: 83 ADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKME 142
Query: 260 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 439
L + +L++A E+ +++ EVA RK+ +E +LE+SEER+ A+ + A+Q
Sbjct: 143 LQEMQLKEAKHIAEDSDRKYE----EVA---RKLVILEGELERSEERAEVAESR---ARQ 192
Query: 440 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAE---DADGKSDEVSRKLAFVEDE 610
+E M + L++ +EE + +E +LL E +A+ +++ R +A +E
Sbjct: 193 LEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKT 252
Query: 611 LEVAEDRVKS 640
++ E+ + S
Sbjct: 253 IDDLEETLAS 262
Score = 37.1 bits (82), Expect = 0.065
Identities = 34/161 (21%), Positives = 74/161 (45%), Gaps = 10/161 (6%)
Frame = +2
Query: 92 AIKKKMQAMKLEKDNAM---DKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 262
A + + MK+ ++ AM +K + E Q ++A AE + + E+ +KL +E +L
Sbjct: 119 AADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELER 178
Query: 263 NKNKLEQANKDLEEKEKQLTATEAEVAAL-------NRKVQQIEEDLEKSEERSGTAQQK 421
++ + E A + E++L + + +L + K + EE+++ EE+ A+ +
Sbjct: 179 SEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETR 238
Query: 422 LLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL 544
A++S + + LE +E ++ L + L
Sbjct: 239 AEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLL 279
>AL133410-2|CAI10974.1| 284|Homo sapiens tropomyosin 2 (beta)
protein.
Length = 284
Score = 198 bits (484), Expect = 1e-50
Identities = 98/211 (46%), Positives = 151/211 (71%)
Frame = +2
Query: 86 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 265
MDAIKKKMQ +KL+K+NA+D+A+ E + A R +++ EE + LQKKL E+++
Sbjct: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
Query: 266 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 445
+++A + LE+ EK+ T EA+VA+LNR++Q +EE+L++++ER TA QKL EA+++A
Sbjct: 61 SESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 446 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 625
DE+ R KV+ENRA +DEE+M+ QLKEA+ +AED+D K +EV+RKL +E ELE +E
Sbjct: 121 DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE 180
Query: 626 DRVKSGDAKISXLEXELKVVGNSLKSLEVSE 718
+R + +++ LE EL+ + +LKSL SE
Sbjct: 181 ERAEVAESRARQLEEELRTMDQALKSLMASE 211
Score = 58.8 bits (136), Expect = 2e-08
Identities = 45/190 (23%), Positives = 101/190 (53%), Gaps = 3/190 (1%)
Frame = +2
Query: 80 ATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLI 259
A + ++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + EE +
Sbjct: 83 ADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKME 142
Query: 260 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 439
L + +L++A E+ +++ EVA RK+ +E +LE+SEER+ A+ + A+Q
Sbjct: 143 LQEMQLKEAKHIAEDSDRKYE----EVA---RKLVILEGELERSEERAEVAESR---ARQ 192
Query: 440 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAE---DADGKSDEVSRKLAFVEDE 610
+E M + L++ +EE + +E +LL E +A+ +++ R +A +E
Sbjct: 193 LEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKT 252
Query: 611 LEVAEDRVKS 640
++ E+ + S
Sbjct: 253 IDDLEETLAS 262
Score = 37.1 bits (82), Expect = 0.065
Identities = 34/161 (21%), Positives = 74/161 (45%), Gaps = 10/161 (6%)
Frame = +2
Query: 92 AIKKKMQAMKLEKDNAM---DKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 262
A + + MK+ ++ AM +K + E Q ++A AE + + E+ +KL +E +L
Sbjct: 119 AADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELER 178
Query: 263 NKNKLEQANKDLEEKEKQLTATEAEVAAL-------NRKVQQIEEDLEKSEERSGTAQQK 421
++ + E A + E++L + + +L + K + EE+++ EE+ A+ +
Sbjct: 179 SEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETR 238
Query: 422 LLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL 544
A++S + + LE +E ++ L + L
Sbjct: 239 AEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLL 279
>AF209746-1|AAF17621.1| 257|Homo sapiens beta tropomyosin protein.
Length = 257
Score = 198 bits (484), Expect = 1e-50
Identities = 98/211 (46%), Positives = 151/211 (71%)
Frame = +2
Query: 86 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 265
MDAIKKKMQ +KL+K+NA+D+A+ E + A R +++ EE + LQKKL E+++
Sbjct: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
Query: 266 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 445
+++A + LE+ EK+ T EA+VA+LNR++Q +EE+L++++ER TA QKL EA+++A
Sbjct: 61 SESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 446 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 625
DE+ R KV+ENRA +DEE+M+ QLKEA+ +AED+D K +EV+RKL +E ELE +E
Sbjct: 121 DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE 180
Query: 626 DRVKSGDAKISXLEXELKVVGNSLKSLEVSE 718
+R + +++ LE EL+ + +LKSL SE
Sbjct: 181 ERAEVAESRARQLEEELRTMDQALKSLMASE 211
>M19267-1|AAA36771.1| 284|Homo sapiens protein ( Human tropomyosin
mRNA, complete cds. ).
Length = 284
Score = 198 bits (483), Expect = 2e-50
Identities = 98/213 (46%), Positives = 153/213 (71%)
Frame = +2
Query: 86 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 265
MDAIKKKMQ +KL+K+NA+D+A+ E + A R++++ +E+ LQKKL E++L
Sbjct: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
Query: 266 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 445
L+ A + LE EK+ T EA+VA+LNR++Q +EE+L++++ER TA QKL EA+++A
Sbjct: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 446 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 625
DE+ R KV+E+RAQ+DEE+M+ QLKEA+ +AEDAD K +EV+RKL +E +LE AE
Sbjct: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
Query: 626 DRVKSGDAKISXLEXELKVVGNSLKSLEVSEXK 724
+R + + ++ LE +L+++ +LK+L +E K
Sbjct: 181 ERAELSEGQVRQLEEQLRIMDQTLKALMAAEDK 213
Score = 60.5 bits (140), Expect = 6e-09
Identities = 46/190 (24%), Positives = 103/190 (54%), Gaps = 7/190 (3%)
Frame = +2
Query: 80 ATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLI 259
A + ++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + EE +
Sbjct: 83 ADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKME 142
Query: 260 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERS--GTAQQKLLEA 433
+ + +L++A E+ +++ EVA RK+ IE DLE++EER+ Q + LE
Sbjct: 143 IQEIQLKEAKHIAEDADRKYE----EVA---RKLVIIESDLERAEERAELSEGQVRQLEE 195
Query: 434 Q-QSADENNRMCKVLENRAQQDEERMDQ----LTNQLKEARLLAEDADGKSDEVSRKLAF 598
Q + D+ + E++ Q E+R ++ L+++LKEA AE A+ ++ + +
Sbjct: 196 QLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDD 255
Query: 599 VEDELEVAED 628
+E+++ A++
Sbjct: 256 LEEKVAHAKE 265
Score = 32.3 bits (70), Expect = 1.8
Identities = 21/104 (20%), Positives = 51/104 (49%), Gaps = 7/104 (6%)
Frame = +2
Query: 89 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQ-------KKLAQVE 247
+ + +K+ ++ + + A ++A+ E Q R + +++ ++ L +K + E
Sbjct: 163 EEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYE 222
Query: 248 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEED 379
E++ + +KL++A E E+ +T E + L KV +E+
Sbjct: 223 EEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEE 266
>BC007433-1|AAH07433.1| 284|Homo sapiens tropomyosin 1 (alpha)
protein.
Length = 284
Score = 198 bits (483), Expect = 2e-50
Identities = 98/213 (46%), Positives = 153/213 (71%)
Frame = +2
Query: 86 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 265
MDAIKKKMQ +KL+K+NA+D+A+ E + A R++++ +E+ LQKKL E++L
Sbjct: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
Query: 266 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 445
L+ A + LE EK+ T EA+VA+LNR++Q +EE+L++++ER TA QKL EA+++A
Sbjct: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 446 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 625
DE+ R KV+E+RAQ+DEE+M+ QLKEA+ +AEDAD K +EV+RKL +E +LE AE
Sbjct: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
Query: 626 DRVKSGDAKISXLEXELKVVGNSLKSLEVSEXK 724
+R + + ++ LE +L+++ +LK+L +E K
Sbjct: 181 ERAELSEGQVRQLEEQLRIMDQTLKALMAAEDK 213
Score = 64.1 bits (149), Expect = 5e-10
Identities = 49/194 (25%), Positives = 104/194 (53%), Gaps = 7/194 (3%)
Frame = +2
Query: 80 ATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLI 259
A + ++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + EE +
Sbjct: 83 ADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKME 142
Query: 260 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERS--GTAQQKLLEA 433
+ + +L++A E+ +++ EVA RK+ IE DLE++EER+ Q + LE
Sbjct: 143 IQEIQLKEAKHIAEDADRKYE----EVA---RKLVIIESDLERAEERAELSEGQVRQLEE 195
Query: 434 Q-QSADENNRMCKVLENRAQQDEERMDQ----LTNQLKEARLLAEDADGKSDEVSRKLAF 598
Q + D+ + E++ Q E+R ++ L+++LKEA AE A+ ++ + +
Sbjct: 196 QLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDD 255
Query: 599 VEDELEVAEDRVKS 640
+EDEL + + K+
Sbjct: 256 LEDELYAQKLKYKA 269
>AK223258-1|BAD96978.1| 284|Homo sapiens tropomyosin 2 (beta)
isoform 2 variant protein.
Length = 284
Score = 196 bits (479), Expect = 5e-50
Identities = 97/211 (45%), Positives = 151/211 (71%)
Frame = +2
Query: 86 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 265
MDAIKKKMQ +KL+K+NA+D+A+ E + A R +++ EE + LQKKL E+++
Sbjct: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
Query: 266 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 445
+++A + LE+ EK+ T EA+VA+L+R++Q +EE+L++++ER TA QKL EA+++A
Sbjct: 61 SESVKEAQEKLEQAEKKATDAEADVASLSRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 446 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 625
DE+ R KV+ENRA +DEE+M+ QLKEA+ +AED+D K +EV+RKL +E ELE +E
Sbjct: 121 DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE 180
Query: 626 DRVKSGDAKISXLEXELKVVGNSLKSLEVSE 718
+R + +++ LE EL+ + +LKSL SE
Sbjct: 181 ERAEVAESRARQLEEELRTMDQALKSLMASE 211
Score = 58.8 bits (136), Expect = 2e-08
Identities = 45/190 (23%), Positives = 101/190 (53%), Gaps = 3/190 (1%)
Frame = +2
Query: 80 ATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLI 259
A + ++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + EE +
Sbjct: 83 ADVASLSRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKME 142
Query: 260 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 439
L + +L++A E+ +++ EVA RK+ +E +LE+SEER+ A+ + A+Q
Sbjct: 143 LQEMQLKEAKHIAEDSDRKYE----EVA---RKLVILEGELERSEERAEVAESR---ARQ 192
Query: 440 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAE---DADGKSDEVSRKLAFVEDE 610
+E M + L++ +EE + +E +LL E +A+ +++ R +A +E
Sbjct: 193 LEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKT 252
Query: 611 LEVAEDRVKS 640
++ E+ + S
Sbjct: 253 IDDLEETLAS 262
Score = 37.1 bits (82), Expect = 0.065
Identities = 34/161 (21%), Positives = 74/161 (45%), Gaps = 10/161 (6%)
Frame = +2
Query: 92 AIKKKMQAMKLEKDNAM---DKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 262
A + + MK+ ++ AM +K + E Q ++A AE + + E+ +KL +E +L
Sbjct: 119 AADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELER 178
Query: 263 NKNKLEQANKDLEEKEKQLTATEAEVAAL-------NRKVQQIEEDLEKSEERSGTAQQK 421
++ + E A + E++L + + +L + K + EE+++ EE+ A+ +
Sbjct: 179 SEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETR 238
Query: 422 LLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL 544
A++S + + LE +E ++ L + L
Sbjct: 239 AEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLL 279
>AY640414-1|AAT68294.1| 284|Homo sapiens sarcomeric tropomyosin
kappa protein.
Length = 284
Score = 188 bits (459), Expect = 1e-47
Identities = 97/213 (45%), Positives = 145/213 (68%)
Frame = +2
Query: 86 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 265
MDAIKKKMQ +KL+K+NA+D+A+ E + A R++++ E++ +K L E++
Sbjct: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRV 60
Query: 266 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 445
+L +A L E+ EA+VA+LNR++Q +EE+L++++ER TA QKL EA+++A
Sbjct: 61 LEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 446 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 625
DE+ R KV+E+RAQ+DEE+M+ QLKEA+ +AEDAD K +EV+RKL +E +LE AE
Sbjct: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
Query: 626 DRVKSGDAKISXLEXELKVVGNSLKSLEVSEXK 724
+R + + K + LE ELK V N LKSLE K
Sbjct: 181 ERAELSEGKCAELEEELKTVTNDLKSLEAQAEK 213
Score = 68.1 bits (159), Expect = 3e-11
Identities = 45/209 (21%), Positives = 106/209 (50%)
Frame = +2
Query: 80 ATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLI 259
A + ++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + EE +
Sbjct: 83 ADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKME 142
Query: 260 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 439
+ + +L++A E+ +++ EVA RK+ IE DLE++EER+ ++ K E ++
Sbjct: 143 IQEIQLKEAKHIAEDADRKYE----EVA---RKLVIIESDLERAEERAELSEGKCAELEE 195
Query: 440 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 619
K LE +A++ ++ D+ ++K ++A+ +++ R + +E ++
Sbjct: 196 ELKTVTNDLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDD 255
Query: 620 AEDRVKSGDAKISXLEXELKVVGNSLKSL 706
ED + + K + EL N + S+
Sbjct: 256 LEDELYAQKLKYKAISEELDHALNDMTSI 284
>AK131384-1|BAD18535.1| 326|Homo sapiens protein ( Homo sapiens
cDNA FLJ16459 fis, clone BRCAN2002473, moderately
similar to Tropomyosin, fibroblast isoform 2. ).
Length = 326
Score = 175 bits (427), Expect = 1e-43
Identities = 93/211 (44%), Positives = 139/211 (65%)
Frame = +2
Query: 92 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN 271
A +K ++ + E+D +++ E A A K+ +E+ LQKKL E++L
Sbjct: 45 AKEKLLRVSEDERDRVLEELHKAEDSLLAAEEAAAKLEDELVSLQKKLKGTEDELDKYSE 104
Query: 272 KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADE 451
L+ A + LE EK+ T EA+VA+LNR++Q +EE+L++++ER TA QKL EA+++ADE
Sbjct: 105 ALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADE 164
Query: 452 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDR 631
+ R KV+E+RAQ+DEE+M+ QLKEA+ +AEDAD K +EV+RKL +E +LE AE+R
Sbjct: 165 SERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEER 224
Query: 632 VKSGDAKISXLEXELKVVGNSLKSLEVSEXK 724
+ + K + LE ELK V N+LKSLE K
Sbjct: 225 AELSEGKCAELEEELKTVTNNLKSLEAQAEK 255
Score = 98.3 bits (234), Expect = 2e-20
Identities = 56/184 (30%), Positives = 100/184 (54%)
Frame = +2
Query: 86 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 265
MDAIKKKMQ +KL+K+NA+D+A+ E + A R++++ E++ +K L E++
Sbjct: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRV 60
Query: 266 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 445
+L +A L E+ E E+ +L +K++ E++L+K E AQ+KL A++ A
Sbjct: 61 LEELHKAEDSLLAAEEAAAKLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKA 120
Query: 446 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 625
+ L R Q EE +D+ +L A E+A+ +DE R + +E + E
Sbjct: 121 TDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDE 180
Query: 626 DRVK 637
++++
Sbjct: 181 EKME 184
Score = 63.3 bits (147), Expect = 9e-10
Identities = 40/185 (21%), Positives = 98/185 (52%)
Frame = +2
Query: 80 ATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLI 259
A + ++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + EE +
Sbjct: 125 ADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKME 184
Query: 260 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 439
+ + +L++A E+ +++ EVA RK+ IE DLE++EER+ ++ K E ++
Sbjct: 185 IQEIQLKEAKHIAEDADRKYE----EVA---RKLVIIESDLERAEERAELSEGKCAELEE 237
Query: 440 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 619
K LE +A++ ++ D+ ++K ++A+ +++ R + +E ++
Sbjct: 238 ELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDD 297
Query: 620 AEDRV 634
E++V
Sbjct: 298 LEEKV 302
Score = 58.0 bits (134), Expect = 3e-08
Identities = 43/176 (24%), Positives = 91/176 (51%), Gaps = 7/176 (3%)
Frame = +2
Query: 221 LQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEER 400
++KK+ ++ D ++ EQA D + E + E ++AA + ++ E++ ++ E
Sbjct: 4 IKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEE 63
Query: 401 SGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEAR---LLAE----DA 559
A+ LL A+++A + L+ + + E+ +D+ + LK+A+ LAE DA
Sbjct: 64 LHKAEDSLLAAEEAAAKLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDA 123
Query: 560 DGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXKA 727
+ ++R++ VE+EL+ A++R+ + + LE K S + ++V E +A
Sbjct: 124 EADVASLNRRIQLVEEELDRAQERLATA---LQKLEEAEKAADESERGMKVIESRA 176
>M19714-1|AAA61226.1| 264|Homo sapiens TPM1 protein.
Length = 264
Score = 172 bits (418), Expect = 1e-42
Identities = 89/193 (46%), Positives = 133/193 (68%)
Frame = +2
Query: 146 KADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTA 325
+A+ E + A R++++ +E+ LQKKL E++L L+ A + LE EK+ T
Sbjct: 1 RAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATD 60
Query: 326 TEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEER 505
EA+VA+LNR++Q +EE+L++++ER TA QKL EA+++ADE+ R KV+E+RAQ+DEE+
Sbjct: 61 AEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEK 120
Query: 506 MDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVV 685
M+ QLKEA+ +AEDAD K +EV+RKL +E +LE AE+R + + K + LE ELK V
Sbjct: 121 MEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTV 180
Query: 686 GNSLKSLEVSEXK 724
N+LKSLE K
Sbjct: 181 TNNLKSLEAQAEK 193
Score = 68.5 bits (160), Expect = 2e-11
Identities = 45/209 (21%), Positives = 106/209 (50%)
Frame = +2
Query: 80 ATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLI 259
A + ++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + EE +
Sbjct: 63 ADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKME 122
Query: 260 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 439
+ + +L++A E+ +++ EVA RK+ IE DLE++EER+ ++ K E ++
Sbjct: 123 IQEIQLKEAKHIAEDADRKYE----EVA---RKLVIIESDLERAEERAELSEGKCAELEE 175
Query: 440 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 619
K LE +A++ ++ D+ ++K ++A+ +++ R + +E ++
Sbjct: 176 ELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDD 235
Query: 620 AEDRVKSGDAKISXLEXELKVVGNSLKSL 706
ED + + K + EL N + S+
Sbjct: 236 LEDELYAQKLKYKAISEELDHALNDMTSM 264
>BC053545-1|AAH53545.1| 245|Homo sapiens tropomyosin 1 (alpha)
protein.
Length = 245
Score = 150 bits (363), Expect = 6e-36
Identities = 74/174 (42%), Positives = 118/174 (67%)
Frame = +2
Query: 203 NEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDL 382
+ + +++K+ ++E + + ++L+ + K EA+VA+LNR++Q +EE+L
Sbjct: 4 SSSLEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEEL 63
Query: 383 EKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDAD 562
++++ER TA QKL EA+++ADE+ R KV+E+RAQ+DEE+M+ QLKEA+ +AEDAD
Sbjct: 64 DRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDAD 123
Query: 563 GKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXK 724
K +EV+RKL +E +LE AE+R + + K + LE ELK V N+LKSLE K
Sbjct: 124 RKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEK 177
Score = 77.4 bits (182), Expect = 5e-14
Identities = 48/218 (22%), Positives = 111/218 (50%), Gaps = 7/218 (3%)
Frame = +2
Query: 77 AATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDL 256
+++++A+++K+++++ + D A ++A T +++ E +V L +++ VEE+L
Sbjct: 4 SSSLEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEEL 63
Query: 257 ILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQ 436
+ +L A + LEE EK +E + + + Q+ EE +E E + A+ +A
Sbjct: 64 DRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDAD 123
Query: 437 QSADENNRMCKVLENRAQQDEERMD-------QLTNQLKEARLLAEDADGKSDEVSRKLA 595
+ +E R ++E+ ++ EER + +L +LK + + ++++ S+K
Sbjct: 124 RKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKED 183
Query: 596 FVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLE 709
E+E++V D++K + + E + + S+ LE
Sbjct: 184 RYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLE 221
Score = 65.7 bits (153), Expect = 2e-10
Identities = 45/204 (22%), Positives = 105/204 (51%)
Frame = +2
Query: 80 ATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLI 259
A + ++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + EE +
Sbjct: 47 ADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKME 106
Query: 260 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 439
+ + +L++A E+ +++ EVA RK+ IE DLE++EER+ ++ K E ++
Sbjct: 107 IQEIQLKEAKHIAEDADRKYE----EVA---RKLVIIESDLERAEERAELSEGKCAELEE 159
Query: 440 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 619
K LE +A++ ++ D+ ++K ++A+ +++ R + +E ++
Sbjct: 160 ELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDD 219
Query: 620 AEDRVKSGDAKISXLEXELKVVGN 691
ED++ + L ELK+ N
Sbjct: 220 LEDQLYQQLEQNRRLTNELKLALN 243
Score = 51.6 bits (118), Expect = 3e-06
Identities = 27/105 (25%), Positives = 55/105 (52%)
Frame = +2
Query: 323 ATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEE 502
A + + A+ RK++ ++E + +EER+GT Q++L ++ + L R Q EE
Sbjct: 2 AGSSSLEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEE 61
Query: 503 RMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVK 637
+D+ +L A E+A+ +DE R + +E + E++++
Sbjct: 62 ELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKME 106
Score = 44.0 bits (99), Expect = 6e-04
Identities = 27/101 (26%), Positives = 49/101 (48%)
Frame = +2
Query: 425 LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVE 604
+ S + R + L+ +A EER L +L R L E A+ ++R++ VE
Sbjct: 1 MAGSSSLEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVE 60
Query: 605 DELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXKA 727
+EL+ A++R+ + + LE K S + ++V E +A
Sbjct: 61 EELDRAQERLATA---LQKLEEAEKAADESERGMKVIESRA 98
>BC050473-1|AAH50473.1| 287|Homo sapiens TPM1 protein protein.
Length = 287
Score = 150 bits (363), Expect = 6e-36
Identities = 74/174 (42%), Positives = 118/174 (67%)
Frame = +2
Query: 203 NEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDL 382
+ + +++K+ ++E + + ++L+ + K EA+VA+LNR++Q +EE+L
Sbjct: 46 SSSLEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEEL 105
Query: 383 EKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDAD 562
++++ER TA QKL EA+++ADE+ R KV+E+RAQ+DEE+M+ QLKEA+ +AEDAD
Sbjct: 106 DRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDAD 165
Query: 563 GKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXK 724
K +EV+RKL +E +LE AE+R + + K + LE ELK V N+LKSLE K
Sbjct: 166 RKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEK 219
Score = 77.4 bits (182), Expect = 5e-14
Identities = 48/218 (22%), Positives = 111/218 (50%), Gaps = 7/218 (3%)
Frame = +2
Query: 77 AATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDL 256
+++++A+++K+++++ + D A ++A T +++ E +V L +++ VEE+L
Sbjct: 46 SSSLEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEEL 105
Query: 257 ILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQ 436
+ +L A + LEE EK +E + + + Q+ EE +E E + A+ +A
Sbjct: 106 DRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDAD 165
Query: 437 QSADENNRMCKVLENRAQQDEERMD-------QLTNQLKEARLLAEDADGKSDEVSRKLA 595
+ +E R ++E+ ++ EER + +L +LK + + ++++ S+K
Sbjct: 166 RKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKED 225
Query: 596 FVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLE 709
E+E++V D++K + + E + + S+ LE
Sbjct: 226 RYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLE 263
Score = 65.7 bits (153), Expect = 2e-10
Identities = 45/204 (22%), Positives = 105/204 (51%)
Frame = +2
Query: 80 ATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLI 259
A + ++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + EE +
Sbjct: 89 ADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKME 148
Query: 260 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 439
+ + +L++A E+ +++ EVA RK+ IE DLE++EER+ ++ K E ++
Sbjct: 149 IQEIQLKEAKHIAEDADRKYE----EVA---RKLVIIESDLERAEERAELSEGKCAELEE 201
Query: 440 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 619
K LE +A++ ++ D+ ++K ++A+ +++ R + +E ++
Sbjct: 202 ELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDD 261
Query: 620 AEDRVKSGDAKISXLEXELKVVGN 691
ED++ + L ELK+ N
Sbjct: 262 LEDQLYQQLEQNRRLTNELKLALN 285
Score = 51.6 bits (118), Expect = 3e-06
Identities = 27/105 (25%), Positives = 55/105 (52%)
Frame = +2
Query: 323 ATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEE 502
A + + A+ RK++ ++E + +EER+GT Q++L ++ + L R Q EE
Sbjct: 44 AGSSSLEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEE 103
Query: 503 RMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVK 637
+D+ +L A E+A+ +DE R + +E + E++++
Sbjct: 104 ELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKME 148
Score = 44.0 bits (99), Expect = 6e-04
Identities = 27/101 (26%), Positives = 49/101 (48%)
Frame = +2
Query: 425 LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVE 604
+ S + R + L+ +A EER L +L R L E A+ ++R++ VE
Sbjct: 43 MAGSSSLEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVE 102
Query: 605 DELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXKA 727
+EL+ A++R+ + + LE K S + ++V E +A
Sbjct: 103 EELDRAQERLATA---LQKLEEAEKAADESERGMKVIESRA 140
>Z24727-1|CAA80853.1| 243|Homo sapiens tropomyosin isoform protein.
Length = 243
Score = 148 bits (358), Expect = 2e-35
Identities = 73/160 (45%), Positives = 115/160 (71%)
Frame = +2
Query: 245 EEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL 424
E++L L+ A + LE EK+ T EA+VA+LNR++Q +EE+L++++ER TA QKL
Sbjct: 17 EDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKL 76
Query: 425 LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVE 604
EA+++ADE+ R KV+E+RAQ+DEE+M+ QLKEA+ +AEDAD K +EV+RKL +E
Sbjct: 77 EEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIE 136
Query: 605 DELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXK 724
+LE AE+R + + ++ LE +L+++ +LK+L +E K
Sbjct: 137 SDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDK 176
Score = 65.3 bits (152), Expect = 2e-10
Identities = 55/216 (25%), Positives = 104/216 (48%), Gaps = 7/216 (3%)
Frame = +2
Query: 83 TMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 262
T D + K +A+K +A +K + E++A DA +V L +++ VEE+L
Sbjct: 16 TEDELDKYSEALK----DAQEKLELAEKKATDAEA-------DVASLNRRIQLVEEELDR 64
Query: 263 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 442
+ +L A + LEE EK +E + + + Q+ EE +E E + A+ +A +
Sbjct: 65 AQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRK 124
Query: 443 ADENNRMCKVLENRAQQDEERMDQLTNQLK--EARLLAEDADGKS-----DEVSRKLAFV 601
+E R ++E+ ++ EER + Q++ E +L D K+ D+ S+K
Sbjct: 125 YEEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRY 184
Query: 602 EDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLE 709
E+E++V D++K + + E + + S+ LE
Sbjct: 185 EEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLE 220
Score = 59.3 bits (137), Expect = 1e-08
Identities = 45/185 (24%), Positives = 100/185 (54%), Gaps = 7/185 (3%)
Frame = +2
Query: 80 ATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLI 259
A + ++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + EE +
Sbjct: 46 ADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKME 105
Query: 260 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERS--GTAQQKLLEA 433
+ + +L++A E+ +++ EVA RK+ IE DLE++EER+ Q + LE
Sbjct: 106 IQEIQLKEAKHIAEDADRKYE----EVA---RKLVIIESDLERAEERAELSEGQVRQLEE 158
Query: 434 Q-QSADENNRMCKVLENRAQQDEERMDQ----LTNQLKEARLLAEDADGKSDEVSRKLAF 598
Q + D+ + E++ Q E+R ++ L+++LKEA AE A+ ++ + +
Sbjct: 159 QLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDD 218
Query: 599 VEDEL 613
+E+++
Sbjct: 219 LEEKV 223
Score = 34.7 bits (76), Expect = 0.35
Identities = 22/87 (25%), Positives = 43/87 (49%)
Frame = +2
Query: 467 KVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGD 646
K E+ + E + +L+ A A DA+ ++R++ VE+EL+ A++R+ +
Sbjct: 14 KGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATA- 72
Query: 647 AKISXLEXELKVVGNSLKSLEVSEXKA 727
+ LE K S + ++V E +A
Sbjct: 73 --LQKLEEAEKAADESERGMKVIESRA 97
>AB209041-1|BAD92278.1| 303|Homo sapiens TPM1 protein variant
protein.
Length = 303
Score = 147 bits (356), Expect = 4e-35
Identities = 73/174 (41%), Positives = 117/174 (67%)
Frame = +2
Query: 203 NEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDL 382
+ + +++K+ ++E + + ++L+ + K EA+VA+LNR++Q +EE+L
Sbjct: 62 SSSLEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEEL 121
Query: 383 EKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDAD 562
++++ER TA QKL EA+++AD + R KV+E+RAQ+DEE+M+ QLKEA+ +AEDAD
Sbjct: 122 DRAQERLATALQKLEEAEKAADGSERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDAD 181
Query: 563 GKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXK 724
K +EV+RKL +E +LE AE+R + + K + LE ELK V N+LKSLE K
Sbjct: 182 RKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEK 235
Score = 77.8 bits (183), Expect = 4e-14
Identities = 48/218 (22%), Positives = 111/218 (50%), Gaps = 7/218 (3%)
Frame = +2
Query: 77 AATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDL 256
+++++A+++K+++++ + D A ++A T +++ E +V L +++ VEE+L
Sbjct: 62 SSSLEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEEL 121
Query: 257 ILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQ 436
+ +L A + LEE EK +E + + + Q+ EE +E E + A+ +A
Sbjct: 122 DRAQERLATALQKLEEAEKAADGSERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDAD 181
Query: 437 QSADENNRMCKVLENRAQQDEERMD-------QLTNQLKEARLLAEDADGKSDEVSRKLA 595
+ +E R ++E+ ++ EER + +L +LK + + ++++ S+K
Sbjct: 182 RKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKED 241
Query: 596 FVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLE 709
E+E++V D++K + + E + + S+ LE
Sbjct: 242 RYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLE 279
Score = 64.5 bits (150), Expect = 4e-10
Identities = 45/204 (22%), Positives = 104/204 (50%)
Frame = +2
Query: 80 ATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLI 259
A + ++ +++Q ++ E D A ++ T Q+ +A A+ ++ ++ + + EE +
Sbjct: 105 ADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADGSERGMKVIESRAQKDEEKME 164
Query: 260 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 439
+ + +L++A E+ +++ EVA RK+ IE DLE++EER+ ++ K E ++
Sbjct: 165 IQEIQLKEAKHIAEDADRKYE----EVA---RKLVIIESDLERAEERAELSEGKCAELEE 217
Query: 440 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 619
K LE +A++ ++ D+ ++K ++A+ +++ R + +E ++
Sbjct: 218 ELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDD 277
Query: 620 AEDRVKSGDAKISXLEXELKVVGN 691
ED++ + L ELK+ N
Sbjct: 278 LEDQLYQQLEQNRRLTNELKLALN 301
Score = 48.8 bits (111), Expect = 2e-05
Identities = 26/105 (24%), Positives = 54/105 (51%)
Frame = +2
Query: 323 ATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEE 502
A + + A+ RK++ ++E + +EER+GT Q++L ++ + L R Q EE
Sbjct: 60 AGSSSLEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEE 119
Query: 503 RMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVK 637
+D+ +L A E+A+ +D R + +E + E++++
Sbjct: 120 ELDRAQERLATALQKLEEAEKAADGSERGMKVIESRAQKDEEKME 164
Score = 44.0 bits (99), Expect = 6e-04
Identities = 27/101 (26%), Positives = 49/101 (48%)
Frame = +2
Query: 425 LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVE 604
+ S + R + L+ +A EER L +L R L E A+ ++R++ VE
Sbjct: 59 MAGSSSLEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVE 118
Query: 605 DELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXKA 727
+EL+ A++R+ + + LE K S + ++V E +A
Sbjct: 119 EELDRAQERLATA---LQKLEEAEKAADGSERGMKVIESRA 156
>AL590431-10|CAH71268.1| 247|Homo sapiens tropomyosin 3 protein.
Length = 247
Score = 146 bits (354), Expect = 7e-35
Identities = 73/171 (42%), Positives = 118/171 (69%)
Frame = +2
Query: 212 VRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKS 391
+ +++K+ +++ + + E+ +++E + + EAEVA+LNR++Q +EE+L+++
Sbjct: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
Query: 392 EERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKS 571
+ER TA QKL EA+++ADE+ R KV+ENRA +DEE+M+ QLKEA+ +AE+AD K
Sbjct: 67 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKY 126
Query: 572 DEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXK 724
+EV+RKL +E +LE E+R + ++K S LE ELK V N+LKSLE K
Sbjct: 127 EEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEK 177
Score = 81.8 bits (193), Expect = 2e-15
Identities = 49/216 (22%), Positives = 108/216 (50%), Gaps = 7/216 (3%)
Frame = +2
Query: 83 TMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 262
T++A+K+K+Q ++ + D+A ++A+ +++ E+ EV L +++ VEE+L
Sbjct: 6 TIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDR 65
Query: 263 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 442
+ +L A + LEE EK +E + + + + EE +E E + A+ EA +
Sbjct: 66 AQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRK 125
Query: 443 ADENNRMCKVLENRAQQDEERMD-------QLTNQLKEARLLAEDADGKSDEVSRKLAFV 601
+E R ++E ++ EER + +L +LK + + ++++ S+K
Sbjct: 126 YEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKY 185
Query: 602 EDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLE 709
E+E+++ D++K + + E + + ++ LE
Sbjct: 186 EEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLE 221
Score = 73.7 bits (173), Expect = 6e-13
Identities = 51/210 (24%), Positives = 110/210 (52%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
+Q A + ++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + E
Sbjct: 43 EQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDE 102
Query: 248 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 427
E + L + +L++A EE +++ EVA RK+ IE DLE++EER+ A+ K
Sbjct: 103 EKMELQEIQLKEAKHIAEEADRKYE----EVA---RKLVIIEGDLERTEERAELAESKCS 155
Query: 428 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 607
E ++ K LE +A++ ++ D+ ++K ++A+ +++ R +A +E
Sbjct: 156 ELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEK 215
Query: 608 ELEVAEDRVKSGDAKISXLEXELKVVGNSL 697
++ E+R+ S + L ELK+ + L
Sbjct: 216 TIDDLEERLYSQLERNRLLSNELKLTLHDL 245
>AL590431-9|CAH71267.1| 248|Homo sapiens tropomyosin 3 protein.
Length = 248
Score = 146 bits (354), Expect = 7e-35
Identities = 73/171 (42%), Positives = 118/171 (69%)
Frame = +2
Query: 212 VRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKS 391
+ +++K+ +++ + + E+ +++E + + EAEVA+LNR++Q +EE+L+++
Sbjct: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
Query: 392 EERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKS 571
+ER TA QKL EA+++ADE+ R KV+ENRA +DEE+M+ QLKEA+ +AE+AD K
Sbjct: 67 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKY 126
Query: 572 DEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXK 724
+EV+RKL +E +LE E+R + ++K S LE ELK V N+LKSLE K
Sbjct: 127 EEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEK 177
Score = 82.6 bits (195), Expect = 1e-15
Identities = 54/220 (24%), Positives = 106/220 (48%), Gaps = 14/220 (6%)
Frame = +2
Query: 83 TMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 262
T++A+K+K+Q ++ + D+A ++A+ +++ E+ EV L +++ VEE+L
Sbjct: 6 TIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDR 65
Query: 263 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 442
+ +L A + LEE EK +E + + + + EE +E E + A+ EA +
Sbjct: 66 AQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRK 125
Query: 443 ADENNRMCKVLENRAQQDEER--------------MDQLTNQLKEARLLAEDADGKSDEV 580
+E R ++E ++ EER + +TN LK AE K D+
Sbjct: 126 YEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKY 185
Query: 581 SRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLK 700
++ + D+L+ AE R + + ++ LE + + + LK
Sbjct: 186 EEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDKLK 225
Score = 69.7 bits (163), Expect = 1e-11
Identities = 50/194 (25%), Positives = 104/194 (53%), Gaps = 7/194 (3%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
+Q A + ++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + E
Sbjct: 43 EQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDE 102
Query: 248 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 427
E + L + +L++A EE +++ EVA RK+ IE DLE++EER+ A+ K
Sbjct: 103 EKMELQEIQLKEAKHIAEEADRKYE----EVA---RKLVIIEGDLERTEERAELAESKCS 155
Query: 428 EAQQSADENNRMCKVLENRAQQDEERMDQ-------LTNQLKEARLLAEDADGKSDEVSR 586
E ++ K LE +A++ ++ D+ LT++LKEA AE A+ ++ +
Sbjct: 156 ELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEK 215
Query: 587 KLAFVEDELEVAED 628
+ +ED+L+ ++
Sbjct: 216 TIDDLEDKLKCTKE 229
>M19715-1|AAA61227.1| 229|Homo sapiens TPM1 protein.
Length = 229
Score = 146 bits (353), Expect = 9e-35
Identities = 71/150 (47%), Positives = 111/150 (74%)
Frame = +2
Query: 275 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 454
L+ A + LE EK+ T EA+VA+LNR++Q +EE+L++++ER TA QKL EA+++ADE+
Sbjct: 9 LKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADES 68
Query: 455 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRV 634
R KV+E+RAQ+DEE+M+ QLKEA+ +AEDAD K +EV+RKL +E +LE AE+R
Sbjct: 69 ERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERA 128
Query: 635 KSGDAKISXLEXELKVVGNSLKSLEVSEXK 724
+ + ++ LE +L+++ +LK+L +E K
Sbjct: 129 ELSEGQVRQLEEQLRIMDQTLKALMAAEDK 158
Score = 62.9 bits (146), Expect = 1e-09
Identities = 48/202 (23%), Positives = 94/202 (46%), Gaps = 7/202 (3%)
Frame = +2
Query: 125 EKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEE 304
E D + +++ A +A +V L +++ VEE+L + +L A + LEE
Sbjct: 1 ELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEE 60
Query: 305 KEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENR 484
EK +E + + + Q+ EE +E E + A+ +A + +E R ++E+
Sbjct: 61 AEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESD 120
Query: 485 AQQDEERMDQLTNQLK--EARLLAEDADGKS-----DEVSRKLAFVEDELEVAEDRVKSG 643
++ EER + Q++ E +L D K+ D+ S+K E+E++V D++K
Sbjct: 121 LERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEA 180
Query: 644 DAKISXLEXELKVVGNSLKSLE 709
+ + E + + S+ LE
Sbjct: 181 ETRAEFAERSVTKLEKSIDDLE 202
Score = 60.5 bits (140), Expect = 6e-09
Identities = 46/190 (24%), Positives = 103/190 (54%), Gaps = 7/190 (3%)
Frame = +2
Query: 80 ATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLI 259
A + ++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + EE +
Sbjct: 28 ADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKME 87
Query: 260 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERS--GTAQQKLLEA 433
+ + +L++A E+ +++ EVA RK+ IE DLE++EER+ Q + LE
Sbjct: 88 IQEIQLKEAKHIAEDADRKYE----EVA---RKLVIIESDLERAEERAELSEGQVRQLEE 140
Query: 434 Q-QSADENNRMCKVLENRAQQDEERMDQ----LTNQLKEARLLAEDADGKSDEVSRKLAF 598
Q + D+ + E++ Q E+R ++ L+++LKEA AE A+ ++ + +
Sbjct: 141 QLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDD 200
Query: 599 VEDELEVAED 628
+E+++ A++
Sbjct: 201 LEEKVAHAKE 210
Score = 32.3 bits (70), Expect = 1.8
Identities = 21/104 (20%), Positives = 51/104 (49%), Gaps = 7/104 (6%)
Frame = +2
Query: 89 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQ-------KKLAQVE 247
+ + +K+ ++ + + A ++A+ E Q R + +++ ++ L +K + E
Sbjct: 108 EEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYE 167
Query: 248 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEED 379
E++ + +KL++A E E+ +T E + L KV +E+
Sbjct: 168 EEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEE 211
>X05276-1|CAA28888.1| 248|Homo sapiens protein ( Human mRNA for
fibroblast tropomyosin TM30 (pl). ).
Length = 248
Score = 144 bits (349), Expect = 3e-34
Identities = 72/168 (42%), Positives = 117/168 (69%)
Frame = +2
Query: 221 LQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEER 400
+++K+ +++ +++ + ++L+ + ++ E +VAALNR++Q +EE+L++++ER
Sbjct: 10 VKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRAQER 69
Query: 401 SGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEV 580
TA QKL EA+++ADE+ R KV+ENRA +DEE+M+ QLKEA+ +AE+AD K +EV
Sbjct: 70 LATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEV 129
Query: 581 SRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXK 724
+RKL +E ELE AE+R + + K LE ELK V N+LKSLE + K
Sbjct: 130 ARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEK 177
Score = 83.0 bits (196), Expect = 1e-15
Identities = 53/216 (24%), Positives = 105/216 (48%), Gaps = 7/216 (3%)
Frame = +2
Query: 83 TMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 262
+++A+K+K+QA++ + D A D+A +++ R EK +V L +++ VEE+L
Sbjct: 6 SLEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDR 65
Query: 263 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 442
+ +L A + LEE EK +E + + + + EE +E E + A+ EA +
Sbjct: 66 AQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRK 125
Query: 443 ADENNRMCKVLENRAQQDEERMD-------QLTNQLKEARLLAEDADGKSDEVSRKLAFV 601
+E R +LE ++ EER + L +LK + + S++ S K
Sbjct: 126 YEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKY 185
Query: 602 EDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLE 709
E+E+++ D++K + + E + + ++ LE
Sbjct: 186 EEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLE 221
>BT019634-1|AAV38440.1| 248|Homo sapiens tropomyosin 4 protein.
Length = 248
Score = 144 bits (349), Expect = 3e-34
Identities = 72/168 (42%), Positives = 117/168 (69%)
Frame = +2
Query: 221 LQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEER 400
+++K+ +++ +++ + ++L+ + ++ E +VAALNR++Q +EE+L++++ER
Sbjct: 10 VKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRAQER 69
Query: 401 SGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEV 580
TA QKL EA+++ADE+ R KV+ENRA +DEE+M+ QLKEA+ +AE+AD K +EV
Sbjct: 70 LATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEV 129
Query: 581 SRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXK 724
+RKL +E ELE AE+R + + K LE ELK V N+LKSLE + K
Sbjct: 130 ARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEK 177
Score = 83.0 bits (196), Expect = 1e-15
Identities = 53/216 (24%), Positives = 105/216 (48%), Gaps = 7/216 (3%)
Frame = +2
Query: 83 TMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 262
+++A+K+K+QA++ + D A D+A +++ R EK +V L +++ VEE+L
Sbjct: 6 SLEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDR 65
Query: 263 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 442
+ +L A + LEE EK +E + + + + EE +E E + A+ EA +
Sbjct: 66 AQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRK 125
Query: 443 ADENNRMCKVLENRAQQDEERMD-------QLTNQLKEARLLAEDADGKSDEVSRKLAFV 601
+E R +LE ++ EER + L +LK + + S++ S K
Sbjct: 126 YEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKY 185
Query: 602 EDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLE 709
E+E+++ D++K + + E + + ++ LE
Sbjct: 186 EEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLE 221
>BC067225-1|AAH67225.1| 248|Homo sapiens tropomyosin 4 protein.
Length = 248
Score = 144 bits (349), Expect = 3e-34
Identities = 72/168 (42%), Positives = 117/168 (69%)
Frame = +2
Query: 221 LQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEER 400
+++K+ +++ +++ + ++L+ + ++ E +VAALNR++Q +EE+L++++ER
Sbjct: 10 VKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRAQER 69
Query: 401 SGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEV 580
TA QKL EA+++ADE+ R KV+ENRA +DEE+M+ QLKEA+ +AE+AD K +EV
Sbjct: 70 LATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEV 129
Query: 581 SRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXK 724
+RKL +E ELE AE+R + + K LE ELK V N+LKSLE + K
Sbjct: 130 ARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEK 177
Score = 83.0 bits (196), Expect = 1e-15
Identities = 53/216 (24%), Positives = 105/216 (48%), Gaps = 7/216 (3%)
Frame = +2
Query: 83 TMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 262
+++A+K+K+QA++ + D A D+A +++ R EK +V L +++ VEE+L
Sbjct: 6 SLEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDR 65
Query: 263 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 442
+ +L A + LEE EK +E + + + + EE +E E + A+ EA +
Sbjct: 66 AQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRK 125
Query: 443 ADENNRMCKVLENRAQQDEERMD-------QLTNQLKEARLLAEDADGKSDEVSRKLAFV 601
+E R +LE ++ EER + L +LK + + S++ S K
Sbjct: 126 YEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKY 185
Query: 602 EDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLE 709
E+E+++ D++K + + E + + ++ LE
Sbjct: 186 EEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLE 221
>BC037576-1|AAH37576.1| 248|Homo sapiens tropomyosin 4 protein.
Length = 248
Score = 144 bits (349), Expect = 3e-34
Identities = 72/168 (42%), Positives = 117/168 (69%)
Frame = +2
Query: 221 LQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEER 400
+++K+ +++ +++ + ++L+ + ++ E +VAALNR++Q +EE+L++++ER
Sbjct: 10 VKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRAQER 69
Query: 401 SGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEV 580
TA QKL EA+++ADE+ R KV+ENRA +DEE+M+ QLKEA+ +AE+AD K +EV
Sbjct: 70 LATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEV 129
Query: 581 SRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXK 724
+RKL +E ELE AE+R + + K LE ELK V N+LKSLE + K
Sbjct: 130 ARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEK 177
Score = 83.0 bits (196), Expect = 1e-15
Identities = 53/216 (24%), Positives = 105/216 (48%), Gaps = 7/216 (3%)
Frame = +2
Query: 83 TMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 262
+++A+K+K+QA++ + D A D+A +++ R EK +V L +++ VEE+L
Sbjct: 6 SLEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDR 65
Query: 263 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 442
+ +L A + LEE EK +E + + + + EE +E E + A+ EA +
Sbjct: 66 AQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRK 125
Query: 443 ADENNRMCKVLENRAQQDEERMD-------QLTNQLKEARLLAEDADGKSDEVSRKLAFV 601
+E R +LE ++ EER + L +LK + + S++ S K
Sbjct: 126 YEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKY 185
Query: 602 EDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLE 709
E+E+++ D++K + + E + + ++ LE
Sbjct: 186 EEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLE 221
>AF310722-1|AAK17926.1| 320|Homo sapiens tropomyosin 4-anaplastic
lymphoma kinase fusion protein protein.
Length = 320
Score = 144 bits (349), Expect = 3e-34
Identities = 72/168 (42%), Positives = 117/168 (69%)
Frame = +2
Query: 221 LQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEER 400
+++K+ +++ +++ + ++L+ + ++ E +VAALNR++Q +EE+L++++ER
Sbjct: 10 VKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRAQER 69
Query: 401 SGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEV 580
TA QKL EA+++ADE+ R KV+ENRA +DEE+M+ QLKEA+ +AE+AD K +EV
Sbjct: 70 LATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEV 129
Query: 581 SRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXK 724
+RKL +E ELE AE+R + + K LE ELK V N+LKSLE + K
Sbjct: 130 ARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEK 177
Score = 85.4 bits (202), Expect = 2e-16
Identities = 55/221 (24%), Positives = 107/221 (48%), Gaps = 7/221 (3%)
Frame = +2
Query: 83 TMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 262
+++A+K+K+QA++ + D A D+A +++ R EK +V L +++ VEE+L
Sbjct: 6 SLEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDR 65
Query: 263 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 442
+ +L A + LEE EK +E + + + + EE +E E + A+ EA +
Sbjct: 66 AQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRK 125
Query: 443 ADENNRMCKVLENRAQQDEERMD-------QLTNQLKEARLLAEDADGKSDEVSRKLAFV 601
+E R +LE ++ EER + L +LK + + S++ S K
Sbjct: 126 YEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKY 185
Query: 602 EDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXK 724
E+E+++ D++K + + E + + ++ LEV K
Sbjct: 186 EEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEVYRRK 226
>AF186109-1|AAG17014.1| 237|Homo sapiens TPM4-ALK fusion
oncoprotein type 2 protein.
Length = 237
Score = 144 bits (349), Expect = 3e-34
Identities = 72/168 (42%), Positives = 117/168 (69%)
Frame = +2
Query: 221 LQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEER 400
+++K+ +++ +++ + ++L+ + ++ E +VAALNR++Q +EE+L++++ER
Sbjct: 10 VKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRAQER 69
Query: 401 SGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEV 580
TA QKL EA+++ADE+ R KV+ENRA +DEE+M+ QLKEA+ +AE+AD K +EV
Sbjct: 70 LATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEV 129
Query: 581 SRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXK 724
+RKL +E ELE AE+R + + K LE ELK V N+LKSLE + K
Sbjct: 130 ARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEK 177
Score = 85.4 bits (202), Expect = 2e-16
Identities = 55/221 (24%), Positives = 107/221 (48%), Gaps = 7/221 (3%)
Frame = +2
Query: 83 TMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 262
+++A+K+K+QA++ + D A D+A +++ R EK +V L +++ VEE+L
Sbjct: 6 SLEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDR 65
Query: 263 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 442
+ +L A + LEE EK +E + + + + EE +E E + A+ EA +
Sbjct: 66 AQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRK 125
Query: 443 ADENNRMCKVLENRAQQDEERMD-------QLTNQLKEARLLAEDADGKSDEVSRKLAFV 601
+E R +LE ++ EER + L +LK + + S++ S K
Sbjct: 126 YEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKY 185
Query: 602 EDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXK 724
E+E+++ D++K + + E + + ++ LEV K
Sbjct: 186 EEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEVYRRK 226
>DQ424903-1|ABD83668.1| 245|Homo sapiens tropomyosin 1 alpha
variant 6 protein.
Length = 245
Score = 143 bits (347), Expect = 5e-34
Identities = 68/174 (39%), Positives = 119/174 (68%)
Frame = +2
Query: 203 NEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDL 382
+ + +++K+ ++E + + ++L+ + K EA+VA+LNR++Q +EE+L
Sbjct: 4 SSSLEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEEL 63
Query: 383 EKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDAD 562
++++ER TA QKL EA+++ADE+ R KV+E+RAQ+DEE+M+ QLKEA+ +AEDAD
Sbjct: 64 DRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDAD 123
Query: 563 GKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXK 724
K +EV+RKL +E +LE AE+R + + ++ LE +L+++ +LK+L +E K
Sbjct: 124 RKYEEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDK 177
Score = 74.9 bits (176), Expect = 3e-13
Identities = 51/218 (23%), Positives = 110/218 (50%), Gaps = 7/218 (3%)
Frame = +2
Query: 77 AATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDL 256
+++++A+++K+++++ + D A ++A T +++ E +V L +++ VEE+L
Sbjct: 4 SSSLEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEEL 63
Query: 257 ILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQ 436
+ +L A + LEE EK +E + + + Q+ EE +E E + A+ +A
Sbjct: 64 DRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDAD 123
Query: 437 QSADENNRMCKVLENRAQQDEERMDQLTNQLK--EARLLAEDADGKS-----DEVSRKLA 595
+ +E R ++E+ ++ EER + Q++ E +L D K+ D+ S+K
Sbjct: 124 RKYEEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKED 183
Query: 596 FVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLE 709
E+E++V D+ K + + E + + S+ LE
Sbjct: 184 RYEEEIKVLSDKPKEAETRAEFAERSVTKLEKSIDDLE 221
Score = 60.9 bits (141), Expect = 5e-09
Identities = 49/205 (23%), Positives = 110/205 (53%), Gaps = 9/205 (4%)
Frame = +2
Query: 80 ATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLI 259
A + ++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + EE +
Sbjct: 47 ADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKME 106
Query: 260 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERS--GTAQQKLLEA 433
+ + +L++A E+ +++ EVA RK+ IE DLE++EER+ Q + LE
Sbjct: 107 IQEIQLKEAKHIAEDADRKYE----EVA---RKLVIIESDLERAEERAELSEGQVRQLEE 159
Query: 434 Q-QSADENNRMCKVLENRAQQDEERMDQ----LTNQLKEARLLAEDADGKSDEVSRKLAF 598
Q + D+ + E++ Q E+R ++ L+++ KEA AE A+ ++ + +
Sbjct: 160 QLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKPKEAETRAEFAERSVTKLEKSIDD 219
Query: 599 VEDEL--EVAEDRVKSGDAKISXLE 667
+ED+L ++ ++R + + K++ E
Sbjct: 220 LEDQLYQQLEQNRRLTNELKLALNE 244
Score = 51.6 bits (118), Expect = 3e-06
Identities = 27/105 (25%), Positives = 55/105 (52%)
Frame = +2
Query: 323 ATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEE 502
A + + A+ RK++ ++E + +EER+GT Q++L ++ + L R Q EE
Sbjct: 2 AGSSSLEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEE 61
Query: 503 RMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVK 637
+D+ +L A E+A+ +DE R + +E + E++++
Sbjct: 62 ELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKME 106
Score = 44.0 bits (99), Expect = 6e-04
Identities = 27/101 (26%), Positives = 49/101 (48%)
Frame = +2
Query: 425 LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVE 604
+ S + R + L+ +A EER L +L R L E A+ ++R++ VE
Sbjct: 1 MAGSSSLEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVE 60
Query: 605 DELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXKA 727
+EL+ A++R+ + + LE K S + ++V E +A
Sbjct: 61 EELDRAQERLATA---LQKLEEAEKAADESERGMKVIESRA 98
>BC002827-1|AAH02827.1| 248|Homo sapiens tropomyosin 4 protein.
Length = 248
Score = 143 bits (346), Expect = 7e-34
Identities = 72/168 (42%), Positives = 116/168 (69%)
Frame = +2
Query: 221 LQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEER 400
+++K+ +++ +++ + ++L+ + ++ E +VAALNR++Q EE+L++++ER
Sbjct: 10 VKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLFEEELDRAQER 69
Query: 401 SGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEV 580
TA QKL EA+++ADE+ R KV+ENRA +DEE+M+ QLKEA+ +AE+AD K +EV
Sbjct: 70 LATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEV 129
Query: 581 SRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXK 724
+RKL +E ELE AE+R + + K LE ELK V N+LKSLE + K
Sbjct: 130 ARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEK 177
Score = 81.0 bits (191), Expect = 4e-15
Identities = 52/216 (24%), Positives = 104/216 (48%), Gaps = 7/216 (3%)
Frame = +2
Query: 83 TMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 262
+++A+K+K+QA++ + D A D+A +++ R EK +V L +++ EE+L
Sbjct: 6 SLEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLFEEELDR 65
Query: 263 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 442
+ +L A + LEE EK +E + + + + EE +E E + A+ EA +
Sbjct: 66 AQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRK 125
Query: 443 ADENNRMCKVLENRAQQDEERMD-------QLTNQLKEARLLAEDADGKSDEVSRKLAFV 601
+E R +LE ++ EER + L +LK + + S++ S K
Sbjct: 126 YEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKY 185
Query: 602 EDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLE 709
E+E+++ D++K + + E + + ++ LE
Sbjct: 186 EEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLE 221
>AF474156-1|AAL84569.1| 203|Homo sapiens TPMsk1 protein.
Length = 203
Score = 141 bits (342), Expect = 2e-33
Identities = 68/144 (47%), Positives = 107/144 (74%)
Frame = +2
Query: 293 DLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKV 472
D E K ++ T EA+VA+LNR++Q +EE+L++++ER TA QKL EA+++ADE+ R KV
Sbjct: 1 DHERKLRETTDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKV 60
Query: 473 LENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAK 652
+E+RAQ+DEE+M+ QLKEA+ +AEDAD K +EV+RKL +E +LE AE+R + + +
Sbjct: 61 IESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGQ 120
Query: 653 ISXLEXELKVVGNSLKSLEVSEXK 724
+ LE +L+++ +LK+L +E K
Sbjct: 121 VRQLEEQLRIMDQTLKALMAAEDK 144
Score = 64.1 bits (149), Expect = 5e-10
Identities = 49/194 (25%), Positives = 104/194 (53%), Gaps = 7/194 (3%)
Frame = +2
Query: 80 ATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLI 259
A + ++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + EE +
Sbjct: 14 ADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKME 73
Query: 260 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERS--GTAQQKLLEA 433
+ + +L++A E+ +++ EVA RK+ IE DLE++EER+ Q + LE
Sbjct: 74 IQEIQLKEAKHIAEDADRKYE----EVA---RKLVIIESDLERAEERAELSEGQVRQLEE 126
Query: 434 Q-QSADENNRMCKVLENRAQQDEERMDQ----LTNQLKEARLLAEDADGKSDEVSRKLAF 598
Q + D+ + E++ Q E+R ++ L+++LKEA AE A+ ++ + +
Sbjct: 127 QLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDD 186
Query: 599 VEDELEVAEDRVKS 640
+EDEL + + K+
Sbjct: 187 LEDELYAQKLKYKA 200
Score = 59.3 bits (137), Expect = 1e-08
Identities = 44/174 (25%), Positives = 85/174 (48%), Gaps = 7/174 (4%)
Frame = +2
Query: 209 EVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEK 388
+V L +++ VEE+L + +L A + LEE EK +E + + + Q+ EE +E
Sbjct: 15 DVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEI 74
Query: 389 SEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLK--EARLLAEDAD 562
E + A+ +A + +E R ++E+ ++ EER + Q++ E +L D
Sbjct: 75 QEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQT 134
Query: 563 GKS-----DEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLE 709
K+ D+ S+K E+E++V D++K + + E + + S+ LE
Sbjct: 135 LKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLE 188
>AL590431-11|CAH71270.1| 242|Homo sapiens tropomyosin 3 protein.
Length = 242
Score = 139 bits (336), Expect = 1e-32
Identities = 75/173 (43%), Positives = 115/173 (66%)
Frame = +2
Query: 206 EEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLE 385
E +++ + L +E+ + + E K EE+ KQL E E+AA+ +K++ E++L+
Sbjct: 2 EAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQL---EDELAAMQKKLKGTEDELD 58
Query: 386 KSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADG 565
+++ER TA QKL EA+++ADE+ R KV+ENRA +DEE+M+ QLKEA+ +AE+AD
Sbjct: 59 RAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADR 118
Query: 566 KSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXK 724
K +EV+RKL +E +LE E+R + ++K S LE ELK V N+LKSLE K
Sbjct: 119 KYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEK 171
Score = 100 bits (240), Expect = 5e-21
Identities = 58/215 (26%), Positives = 115/215 (53%), Gaps = 7/215 (3%)
Frame = +2
Query: 86 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 265
M+AIKKKMQ +KL+K+NA+D+A+ E + + A R++++ +E+ +QKKL E++L
Sbjct: 1 MEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDRA 60
Query: 266 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 445
+ +L A + LEE EK +E + + + + EE +E E + A+ EA +
Sbjct: 61 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKY 120
Query: 446 DENNRMCKVLENRAQQDEERMD-------QLTNQLKEARLLAEDADGKSDEVSRKLAFVE 604
+E R ++E ++ EER + +L +LK + + ++++ S+K E
Sbjct: 121 EEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYE 180
Query: 605 DELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLE 709
+E+++ D++K + + E + + ++ LE
Sbjct: 181 EEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLE 215
>AK092690-1|BAC03946.1| 243|Homo sapiens protein ( Homo sapiens
cDNA FLJ35371 fis, clone SKMUS2001740, highly similar to
TROPOMYOSIN ALPHA CHAIN, SKELETAL MUSCLE TYPE. ).
Length = 243
Score = 139 bits (336), Expect = 1e-32
Identities = 75/173 (43%), Positives = 115/173 (66%)
Frame = +2
Query: 206 EEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLE 385
E +++ + L +E+ + + E K EE+ KQL E E+AA+ +K++ E++L+
Sbjct: 3 EAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQL---EDELAAMQKKLKGTEDELD 59
Query: 386 KSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADG 565
+++ER TA QKL EA+++ADE+ R KV+ENRA +DEE+M+ QLKEA+ +AE+AD
Sbjct: 60 RAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADR 119
Query: 566 KSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXK 724
K +EV+RKL +E +LE E+R + ++K S LE ELK V N+LKSLE K
Sbjct: 120 KYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEK 172
Score = 100 bits (240), Expect = 5e-21
Identities = 58/215 (26%), Positives = 115/215 (53%), Gaps = 7/215 (3%)
Frame = +2
Query: 86 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 265
M+AIKKKMQ +KL+K+NA+D+A+ E + + A R++++ +E+ +QKKL E++L
Sbjct: 2 MEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDRA 61
Query: 266 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 445
+ +L A + LEE EK +E + + + + EE +E E + A+ EA +
Sbjct: 62 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKY 121
Query: 446 DENNRMCKVLENRAQQDEERMD-------QLTNQLKEARLLAEDADGKSDEVSRKLAFVE 604
+E R ++E ++ EER + +L +LK + + ++++ S+K E
Sbjct: 122 EEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYE 181
Query: 605 DELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLE 709
+E+++ D++K + + E + + ++ LE
Sbjct: 182 EEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLE 216
>X12369-1|CAA30930.1| 227|Homo sapiens tropomyosin (227 AA)
protein.
Length = 227
Score = 136 bits (329), Expect = 8e-32
Identities = 66/147 (44%), Positives = 110/147 (74%)
Frame = +2
Query: 284 ANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRM 463
+++ L E++ + TA EA+VA+LNR++Q +EE+L++++ER T QKL EA+++ADE+ R
Sbjct: 11 SSEHLHERKLRETA-EADVASLNRRIQLVEEELDRAQERLATVLQKLEEAEKAADESERG 69
Query: 464 CKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSG 643
KV+E+RAQ+DEE+M+ QLKEA+ +AEDAD K +EV+RKL +E +LE AE+R +
Sbjct: 70 MKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELS 129
Query: 644 DAKISXLEXELKVVGNSLKSLEVSEXK 724
+ ++ LE +L+++ + L+S+ +E K
Sbjct: 130 EGQVRQLEEQLRIMDSDLESINAAEDK 156
Score = 62.1 bits (144), Expect = 2e-09
Identities = 45/179 (25%), Positives = 87/179 (48%), Gaps = 7/179 (3%)
Frame = +2
Query: 194 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIE 373
E +V L +++ VEE+L + +L + LEE EK +E + + + Q+ E
Sbjct: 22 ETAEADVASLNRRIQLVEEELDRAQERLATVLQKLEEAEKAADESERGMKVIESRAQKDE 81
Query: 374 EDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLK--EARLL 547
E +E E + A+ +A + +E R ++E+ ++ EER + Q++ E +L
Sbjct: 82 EKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGQVRQLEEQLR 141
Query: 548 AEDADGKS-----DEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLE 709
D+D +S D+ S+K E+E++V D++K + + E + + S+ LE
Sbjct: 142 IMDSDLESINAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLE 200
Score = 59.3 bits (137), Expect = 1e-08
Identities = 46/190 (24%), Positives = 102/190 (53%), Gaps = 7/190 (3%)
Frame = +2
Query: 80 ATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLI 259
A + ++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + EE +
Sbjct: 26 ADVASLNRRIQLVEEELDRAQERLATVLQKLEEAEKAADESERGMKVIESRAQKDEEKME 85
Query: 260 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERS--GTAQQKLLEA 433
+ + +L++A E+ +++ EVA RK+ IE DLE++EER+ Q + LE
Sbjct: 86 IQEIQLKEAKHIAEDADRKYE----EVA---RKLVIIESDLERAEERAELSEGQVRQLEE 138
Query: 434 Q-QSADENNRMCKVLENRAQQDEERMDQ----LTNQLKEARLLAEDADGKSDEVSRKLAF 598
Q + D + E++ Q E+R ++ L+++LKEA AE A+ ++ + +
Sbjct: 139 QLRIMDSDLESINAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDD 198
Query: 599 VEDELEVAED 628
+E+++ A++
Sbjct: 199 LEEKVAHAKE 208
Score = 34.7 bits (76), Expect = 0.35
Identities = 24/104 (23%), Positives = 51/104 (49%), Gaps = 7/104 (6%)
Frame = +2
Query: 89 DAIKKKMQAMKLEKDNAMDKADTCEQQAR--DANLRA-----EKVNEEVRELQKKLAQVE 247
+ + +K+ ++ + + A ++A+ E Q R + LR E +N + +K + E
Sbjct: 106 EEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDSDLESINAAEDKYSQKEDRYE 165
Query: 248 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEED 379
E++ + +KL++A E E+ +T E + L KV +E+
Sbjct: 166 EEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEE 209
>X04588-1|CAB37185.1| 248|Homo sapiens protein ( Human 2.5 kb mRNA
for cytoskeletal tropomyosin TM30(nm). ).
Length = 248
Score = 135 bits (326), Expect = 2e-31
Identities = 63/171 (36%), Positives = 117/171 (68%)
Frame = +2
Query: 212 VRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKS 391
+ +++K+ +++ + + E+ +++E + + EAEVA+LNR++Q +EE+L+++
Sbjct: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
Query: 392 EERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKS 571
+ER TA QKL EA+++ADE+ R KV+ENRA +DEE+M+ QLKEA+ +AE+AD K
Sbjct: 67 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKY 126
Query: 572 DEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXK 724
+EV+RKL +E +LE E+R + +++ ++ +++++ +LK L +E K
Sbjct: 127 EEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEK 177
Score = 78.6 bits (185), Expect = 2e-14
Identities = 49/216 (22%), Positives = 108/216 (50%), Gaps = 7/216 (3%)
Frame = +2
Query: 83 TMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 262
T++A+K+K+Q ++ + D+A ++A+ +++ E+ EV L +++ VEE+L
Sbjct: 6 TIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDR 65
Query: 263 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 442
+ +L A + LEE EK +E + + + + EE +E E + A+ EA +
Sbjct: 66 AQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRK 125
Query: 443 ADENNRMCKVLENRAQQDEERMDQLTNQLKE----ARLLAED---ADGKSDEVSRKLAFV 601
+E R ++E ++ EER + ++ +E RL+ ++ ++ S+K
Sbjct: 126 YEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKY 185
Query: 602 EDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLE 709
E+E+++ D++K + + E + + ++ LE
Sbjct: 186 EEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLE 221
Score = 69.7 bits (163), Expect = 1e-11
Identities = 49/194 (25%), Positives = 104/194 (53%), Gaps = 7/194 (3%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
+Q A + ++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + E
Sbjct: 43 EQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDE 102
Query: 248 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 427
E + L + +L++A EE +++ EVA RK+ IE DLE++EER+ A+ +
Sbjct: 103 EKMELQEIQLKEAKHIAEEADRKYE----EVA---RKLVIIEGDLERTEERAELAESRCR 155
Query: 428 EAQQS---ADENNRMCKVLENRAQQDEERMDQ----LTNQLKEARLLAEDADGKSDEVSR 586
E + D+N + E + Q E++ ++ LT++LKEA AE A+ ++ +
Sbjct: 156 EMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEK 215
Query: 587 KLAFVEDELEVAED 628
+ +ED+L+ ++
Sbjct: 216 TIDDLEDKLKCTKE 229
>BC072428-1|AAH72428.1| 248|Homo sapiens tropomyosin 3 protein.
Length = 248
Score = 135 bits (326), Expect = 2e-31
Identities = 63/171 (36%), Positives = 117/171 (68%)
Frame = +2
Query: 212 VRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKS 391
+ +++K+ +++ + + E+ +++E + + EAEVA+LNR++Q +EE+L+++
Sbjct: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
Query: 392 EERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKS 571
+ER TA QKL EA+++ADE+ R KV+ENRA +DEE+M+ QLKEA+ +AE+AD K
Sbjct: 67 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKY 126
Query: 572 DEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXK 724
+EV+RKL +E +LE E+R + +++ ++ +++++ +LK L +E K
Sbjct: 127 EEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEK 177
Score = 78.6 bits (185), Expect = 2e-14
Identities = 49/216 (22%), Positives = 108/216 (50%), Gaps = 7/216 (3%)
Frame = +2
Query: 83 TMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 262
T++A+K+K+Q ++ + D+A ++A+ +++ E+ EV L +++ VEE+L
Sbjct: 6 TIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDR 65
Query: 263 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 442
+ +L A + LEE EK +E + + + + EE +E E + A+ EA +
Sbjct: 66 AQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRK 125
Query: 443 ADENNRMCKVLENRAQQDEERMDQLTNQLKE----ARLLAED---ADGKSDEVSRKLAFV 601
+E R ++E ++ EER + ++ +E RL+ ++ ++ S+K
Sbjct: 126 YEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKY 185
Query: 602 EDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLE 709
E+E+++ D++K + + E + + ++ LE
Sbjct: 186 EEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLE 221
Score = 69.7 bits (163), Expect = 1e-11
Identities = 49/194 (25%), Positives = 104/194 (53%), Gaps = 7/194 (3%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
+Q A + ++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + E
Sbjct: 43 EQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDE 102
Query: 248 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 427
E + L + +L++A EE +++ EVA RK+ IE DLE++EER+ A+ +
Sbjct: 103 EKMELQEIQLKEAKHIAEEADRKYE----EVA---RKLVIIEGDLERTEERAELAESRCR 155
Query: 428 EAQQS---ADENNRMCKVLENRAQQDEERMDQ----LTNQLKEARLLAEDADGKSDEVSR 586
E + D+N + E + Q E++ ++ LT++LKEA AE A+ ++ +
Sbjct: 156 EMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEK 215
Query: 587 KLAFVEDELEVAED 628
+ +ED+L+ ++
Sbjct: 216 TIDDLEDKLKCTKE 229
>BC015403-1|AAH15403.1| 248|Homo sapiens tropomyosin 3 protein.
Length = 248
Score = 135 bits (326), Expect = 2e-31
Identities = 63/171 (36%), Positives = 117/171 (68%)
Frame = +2
Query: 212 VRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKS 391
+ +++K+ +++ + + E+ +++E + + EAEVA+LNR++Q +EE+L+++
Sbjct: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
Query: 392 EERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKS 571
+ER TA QKL EA+++ADE+ R KV+ENRA +DEE+M+ QLKEA+ +AE+AD K
Sbjct: 67 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKY 126
Query: 572 DEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXK 724
+EV+RKL +E +LE E+R + +++ ++ +++++ +LK L +E K
Sbjct: 127 EEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEK 177
Score = 78.6 bits (185), Expect = 2e-14
Identities = 49/216 (22%), Positives = 108/216 (50%), Gaps = 7/216 (3%)
Frame = +2
Query: 83 TMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 262
T++A+K+K+Q ++ + D+A ++A+ +++ E+ EV L +++ VEE+L
Sbjct: 6 TIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDR 65
Query: 263 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 442
+ +L A + LEE EK +E + + + + EE +E E + A+ EA +
Sbjct: 66 AQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRK 125
Query: 443 ADENNRMCKVLENRAQQDEERMDQLTNQLKE----ARLLAED---ADGKSDEVSRKLAFV 601
+E R ++E ++ EER + ++ +E RL+ ++ ++ S+K
Sbjct: 126 YEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKY 185
Query: 602 EDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLE 709
E+E+++ D++K + + E + + ++ LE
Sbjct: 186 EEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLE 221
Score = 69.7 bits (163), Expect = 1e-11
Identities = 49/194 (25%), Positives = 104/194 (53%), Gaps = 7/194 (3%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
+Q A + ++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + E
Sbjct: 43 EQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDE 102
Query: 248 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 427
E + L + +L++A EE +++ EVA RK+ IE DLE++EER+ A+ +
Sbjct: 103 EKMELQEIQLKEAKHIAEEADRKYE----EVA---RKLVIIEGDLERTEERAELAESRCR 155
Query: 428 EAQQS---ADENNRMCKVLENRAQQDEERMDQ----LTNQLKEARLLAEDADGKSDEVSR 586
E + D+N + E + Q E++ ++ LT++LKEA AE A+ ++ +
Sbjct: 156 EMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEK 215
Query: 587 KLAFVEDELEVAED 628
+ +ED+L+ ++
Sbjct: 216 TIDDLEDKLKCTKE 229
>BC000771-1|AAH00771.1| 248|Homo sapiens tropomyosin 3 protein.
Length = 248
Score = 135 bits (326), Expect = 2e-31
Identities = 63/171 (36%), Positives = 117/171 (68%)
Frame = +2
Query: 212 VRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKS 391
+ +++K+ +++ + + E+ +++E + + EAEVA+LNR++Q +EE+L+++
Sbjct: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
Query: 392 EERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKS 571
+ER TA QKL EA+++ADE+ R KV+ENRA +DEE+M+ QLKEA+ +AE+AD K
Sbjct: 67 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKY 126
Query: 572 DEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXK 724
+EV+RKL +E +LE E+R + +++ ++ +++++ +LK L +E K
Sbjct: 127 EEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEK 177
Score = 78.6 bits (185), Expect = 2e-14
Identities = 49/216 (22%), Positives = 108/216 (50%), Gaps = 7/216 (3%)
Frame = +2
Query: 83 TMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 262
T++A+K+K+Q ++ + D+A ++A+ +++ E+ EV L +++ VEE+L
Sbjct: 6 TIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDR 65
Query: 263 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 442
+ +L A + LEE EK +E + + + + EE +E E + A+ EA +
Sbjct: 66 AQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRK 125
Query: 443 ADENNRMCKVLENRAQQDEERMDQLTNQLKE----ARLLAED---ADGKSDEVSRKLAFV 601
+E R ++E ++ EER + ++ +E RL+ ++ ++ S+K
Sbjct: 126 YEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKY 185
Query: 602 EDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLE 709
E+E+++ D++K + + E + + ++ LE
Sbjct: 186 EEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLE 221
Score = 69.7 bits (163), Expect = 1e-11
Identities = 49/194 (25%), Positives = 104/194 (53%), Gaps = 7/194 (3%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
+Q A + ++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + E
Sbjct: 43 EQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDE 102
Query: 248 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 427
E + L + +L++A EE +++ EVA RK+ IE DLE++EER+ A+ +
Sbjct: 103 EKMELQEIQLKEAKHIAEEADRKYE----EVA---RKLVIIEGDLERTEERAELAESRCR 155
Query: 428 EAQQS---ADENNRMCKVLENRAQQDEERMDQ----LTNQLKEARLLAEDADGKSDEVSR 586
E + D+N + E + Q E++ ++ LT++LKEA AE A+ ++ +
Sbjct: 156 EMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEK 215
Query: 587 KLAFVEDELEVAED 628
+ +ED+L+ ++
Sbjct: 216 TIDDLEDKLKCTKE 229
>AY004867-1|AAF87083.1| 247|Homo sapiens tropomyosin isoform
protein.
Length = 247
Score = 135 bits (326), Expect = 2e-31
Identities = 63/171 (36%), Positives = 117/171 (68%)
Frame = +2
Query: 212 VRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKS 391
+ +++K+ +++ + + E+ +++E + + EAEVA+LNR++Q +EE+L+++
Sbjct: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
Query: 392 EERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKS 571
+ER TA QKL EA+++ADE+ R KV+ENRA +DEE+M+ QLKEA+ +AE+AD K
Sbjct: 67 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKY 126
Query: 572 DEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXK 724
+EV+RKL +E +LE E+R + +++ ++ +++++ +LK L +E K
Sbjct: 127 EEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEK 177
Score = 78.6 bits (185), Expect = 2e-14
Identities = 49/216 (22%), Positives = 108/216 (50%), Gaps = 7/216 (3%)
Frame = +2
Query: 83 TMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 262
T++A+K+K+Q ++ + D+A ++A+ +++ E+ EV L +++ VEE+L
Sbjct: 6 TIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDR 65
Query: 263 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 442
+ +L A + LEE EK +E + + + + EE +E E + A+ EA +
Sbjct: 66 AQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRK 125
Query: 443 ADENNRMCKVLENRAQQDEERMDQLTNQLKE----ARLLAED---ADGKSDEVSRKLAFV 601
+E R ++E ++ EER + ++ +E RL+ ++ ++ S+K
Sbjct: 126 YEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKY 185
Query: 602 EDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLE 709
E+E+++ D++K + + E + + ++ LE
Sbjct: 186 EEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLE 221
Score = 69.3 bits (162), Expect = 1e-11
Identities = 51/206 (24%), Positives = 110/206 (53%), Gaps = 9/206 (4%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
+Q A + ++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + E
Sbjct: 43 EQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDE 102
Query: 248 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 427
E + L + +L++A EE +++ EVA RK+ IE DLE++EER+ A+ +
Sbjct: 103 EKMELQEIQLKEAKHIAEEADRKYE----EVA---RKLVIIEGDLERTEERAELAESRCR 155
Query: 428 EAQQS---ADENNRMCKVLENRAQQDEERMDQ----LTNQLKEARLLAEDADGKSDEVSR 586
E + D+N + E + Q E++ ++ LT++LKEA AE A+ ++ +
Sbjct: 156 EMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEK 215
Query: 587 KLAFVEDEL--EVAEDRVKSGDAKIS 658
+ +E+ L ++ +R+ S + K++
Sbjct: 216 TIDDLEERLYSQLERNRLLSNELKLT 241
>AL590431-8|CAH71264.1| 248|Homo sapiens tropomyosin 3 protein.
Length = 248
Score = 135 bits (326), Expect = 2e-31
Identities = 63/171 (36%), Positives = 117/171 (68%)
Frame = +2
Query: 212 VRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKS 391
+ +++K+ +++ + + E+ +++E + + EAEVA+LNR++Q +EE+L+++
Sbjct: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
Query: 392 EERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKS 571
+ER TA QKL EA+++ADE+ R KV+ENRA +DEE+M+ QLKEA+ +AE+AD K
Sbjct: 67 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKY 126
Query: 572 DEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXK 724
+EV+RKL +E +LE E+R + +++ ++ +++++ +LK L +E K
Sbjct: 127 EEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEK 177
Score = 78.6 bits (185), Expect = 2e-14
Identities = 49/216 (22%), Positives = 108/216 (50%), Gaps = 7/216 (3%)
Frame = +2
Query: 83 TMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 262
T++A+K+K+Q ++ + D+A ++A+ +++ E+ EV L +++ VEE+L
Sbjct: 6 TIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDR 65
Query: 263 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 442
+ +L A + LEE EK +E + + + + EE +E E + A+ EA +
Sbjct: 66 AQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRK 125
Query: 443 ADENNRMCKVLENRAQQDEERMDQLTNQLKE----ARLLAED---ADGKSDEVSRKLAFV 601
+E R ++E ++ EER + ++ +E RL+ ++ ++ S+K
Sbjct: 126 YEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKY 185
Query: 602 EDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLE 709
E+E+++ D++K + + E + + ++ LE
Sbjct: 186 EEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLE 221
Score = 69.7 bits (163), Expect = 1e-11
Identities = 49/194 (25%), Positives = 104/194 (53%), Gaps = 7/194 (3%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
+Q A + ++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + E
Sbjct: 43 EQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDE 102
Query: 248 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 427
E + L + +L++A EE +++ EVA RK+ IE DLE++EER+ A+ +
Sbjct: 103 EKMELQEIQLKEAKHIAEEADRKYE----EVA---RKLVIIEGDLERTEERAELAESRCR 155
Query: 428 EAQQS---ADENNRMCKVLENRAQQDEERMDQ----LTNQLKEARLLAEDADGKSDEVSR 586
E + D+N + E + Q E++ ++ LT++LKEA AE A+ ++ +
Sbjct: 156 EMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEK 215
Query: 587 KLAFVEDELEVAED 628
+ +ED+L+ ++
Sbjct: 216 TIDDLEDKLKCTKE 229
>AL590431-7|CAH71266.1| 248|Homo sapiens tropomyosin 3 protein.
Length = 248
Score = 135 bits (326), Expect = 2e-31
Identities = 63/171 (36%), Positives = 117/171 (68%)
Frame = +2
Query: 212 VRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKS 391
+ +++K+ +++ + + E+ +++E + + EAEVA+LNR++Q +EE+L+++
Sbjct: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
Query: 392 EERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKS 571
+ER TA QKL EA+++ADE+ R KV+ENRA +DEE+M+ QLKEA+ +AE+AD K
Sbjct: 67 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKY 126
Query: 572 DEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXK 724
+EV+RKL +E +LE E+R + +++ ++ +++++ +LK L +E K
Sbjct: 127 EEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEK 177
Score = 78.6 bits (185), Expect = 2e-14
Identities = 49/216 (22%), Positives = 108/216 (50%), Gaps = 7/216 (3%)
Frame = +2
Query: 83 TMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 262
T++A+K+K+Q ++ + D+A ++A+ +++ E+ EV L +++ VEE+L
Sbjct: 6 TIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDR 65
Query: 263 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 442
+ +L A + LEE EK +E + + + + EE +E E + A+ EA +
Sbjct: 66 AQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRK 125
Query: 443 ADENNRMCKVLENRAQQDEERMDQLTNQLKE----ARLLAED---ADGKSDEVSRKLAFV 601
+E R ++E ++ EER + ++ +E RL+ ++ ++ S+K
Sbjct: 126 YEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKY 185
Query: 602 EDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLE 709
E+E+++ D++K + + E + + ++ LE
Sbjct: 186 EEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLE 221
Score = 70.5 bits (165), Expect = 6e-12
Identities = 51/198 (25%), Positives = 105/198 (53%), Gaps = 7/198 (3%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
+Q A + ++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + E
Sbjct: 43 EQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDE 102
Query: 248 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 427
E + L + +L++A EE +++ EVA RK+ IE DLE++EER+ A+ +
Sbjct: 103 EKMELQEIQLKEAKHIAEEADRKYE----EVA---RKLVIIEGDLERTEERAELAESRCR 155
Query: 428 EAQQS---ADENNRMCKVLENRAQQDEERMDQ----LTNQLKEARLLAEDADGKSDEVSR 586
E + D+N + E + Q E++ ++ LT++LKEA AE A+ ++ +
Sbjct: 156 EMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEK 215
Query: 587 KLAFVEDELEVAEDRVKS 640
+ +EDEL + + K+
Sbjct: 216 TIDDLEDELYAQKLKYKA 233
>AF474157-1|AAL84570.1| 247|Homo sapiens TPMsk3 protein.
Length = 247
Score = 135 bits (326), Expect = 2e-31
Identities = 63/171 (36%), Positives = 117/171 (68%)
Frame = +2
Query: 212 VRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKS 391
+ +++K+ +++ + + E+ +++E + + EAEVA+LNR++Q +EE+L+++
Sbjct: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
Query: 392 EERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKS 571
+ER TA QKL EA+++ADE+ R KV+ENRA +DEE+M+ QLKEA+ +AE+AD K
Sbjct: 67 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKY 126
Query: 572 DEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXK 724
+EV+RKL +E +LE E+R + +++ ++ +++++ +LK L +E K
Sbjct: 127 EEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEK 177
Score = 78.6 bits (185), Expect = 2e-14
Identities = 49/216 (22%), Positives = 108/216 (50%), Gaps = 7/216 (3%)
Frame = +2
Query: 83 TMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 262
T++A+K+K+Q ++ + D+A ++A+ +++ E+ EV L +++ VEE+L
Sbjct: 6 TIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDR 65
Query: 263 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 442
+ +L A + LEE EK +E + + + + EE +E E + A+ EA +
Sbjct: 66 AQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRK 125
Query: 443 ADENNRMCKVLENRAQQDEERMDQLTNQLKE----ARLLAED---ADGKSDEVSRKLAFV 601
+E R ++E ++ EER + ++ +E RL+ ++ ++ S+K
Sbjct: 126 YEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKY 185
Query: 602 EDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLE 709
E+E+++ D++K + + E + + ++ LE
Sbjct: 186 EEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLE 221
Score = 70.5 bits (165), Expect = 6e-12
Identities = 51/198 (25%), Positives = 105/198 (53%), Gaps = 7/198 (3%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
+Q A + ++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + E
Sbjct: 43 EQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDE 102
Query: 248 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 427
E + L + +L++A EE +++ EVA RK+ IE DLE++EER+ A+ +
Sbjct: 103 EKMELQEIQLKEAKHIAEEADRKYE----EVA---RKLVIIEGDLERTEERAELAESRCR 155
Query: 428 EAQQS---ADENNRMCKVLENRAQQDEERMDQ----LTNQLKEARLLAEDADGKSDEVSR 586
E + D+N + E + Q E++ ++ LT++LKEA AE A+ ++ +
Sbjct: 156 EMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEK 215
Query: 587 KLAFVEDELEVAEDRVKS 640
+ +EDEL + + K+
Sbjct: 216 TIDDLEDELYAQKLKYKA 233
>X03541-1|CAA27243.1| 641|Homo sapiens protein ( Human mRNA of trk
oncogene. ).
Length = 641
Score = 133 bits (322), Expect = 5e-31
Identities = 62/171 (36%), Positives = 117/171 (68%)
Frame = +2
Query: 212 VRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKS 391
+ +++K+ +++ + + E+ +++E + + EAEVA+LNR++Q +EE+L+++
Sbjct: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
Query: 392 EERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKS 571
+ER TA QKL EA+++ADE+ R KV+ENRA +DEE+M+ QL+EA+ +AE+AD K
Sbjct: 67 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLEEAKHIAEEADRKY 126
Query: 572 DEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXK 724
+EV+RKL +E +LE E+R + +++ ++ +++++ +LK L +E K
Sbjct: 127 EEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEK 177
Score = 78.6 bits (185), Expect = 2e-14
Identities = 49/216 (22%), Positives = 108/216 (50%), Gaps = 7/216 (3%)
Frame = +2
Query: 83 TMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 262
T++A+K+K+Q ++ + D+A ++A+ +++ E+ EV L +++ VEE+L
Sbjct: 6 TIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDR 65
Query: 263 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 442
+ +L A + LEE EK +E + + + + EE +E E + A+ EA +
Sbjct: 66 AQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLEEAKHIAEEADRK 125
Query: 443 ADENNRMCKVLENRAQQDEERMDQLTNQLKE----ARLLAED---ADGKSDEVSRKLAFV 601
+E R ++E ++ EER + ++ +E RL+ ++ ++ S+K
Sbjct: 126 YEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKY 185
Query: 602 EDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLE 709
E+E+++ D++K + + E + + ++ LE
Sbjct: 186 EEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLE 221
Score = 71.3 bits (167), Expect = 3e-12
Identities = 52/200 (26%), Positives = 104/200 (52%), Gaps = 7/200 (3%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
+Q A + ++ +++Q ++ E D A ++ T Q+ +A A++ ++ ++ + + E
Sbjct: 43 EQAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDE 102
Query: 248 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 427
E + L + +LE+A EE +++ EVA RK+ IE DLE++EER+ A+ +
Sbjct: 103 EKMELQEIQLEEAKHIAEEADRKYE----EVA---RKLVIIEGDLERTEERAELAESRCR 155
Query: 428 EAQQS---ADENNRMCKVLENRAQQDEERMDQ----LTNQLKEARLLAEDADGKSDEVSR 586
E + D+N + E + Q E++ ++ LT++LKEA AE A+ ++ +
Sbjct: 156 EMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEK 215
Query: 587 KLAFVEDELEVAEDRVKSGD 646
+ +ED + D V+ D
Sbjct: 216 TIDDLEDTNSTSGDPVEKKD 235
>AK129882-1|BAC85248.1| 217|Homo sapiens protein ( Homo sapiens
cDNA FLJ26372 fis, clone HRT06233. ).
Length = 217
Score = 131 bits (317), Expect = 2e-30
Identities = 73/197 (37%), Positives = 116/197 (58%)
Frame = +2
Query: 86 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 265
MDAIKKKMQ +KL+K+NA+D+A+ E + A R++++ +E+ LQKKL E++L
Sbjct: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
Query: 266 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 445
L+ A + LE EK+ T EA+VA+LNR++Q +EE+L++++ER TA QKL EA+ S
Sbjct: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAELS- 119
Query: 446 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 625
E + + EE + +TN LK AE K D ++ + D+L+ AE
Sbjct: 120 ----------EGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAE 169
Query: 626 DRVKSGDAKISXLEXEL 676
R + + ++ LE +
Sbjct: 170 TRAEFAERSVTKLEKSI 186
Score = 68.1 bits (159), Expect = 3e-11
Identities = 47/166 (28%), Positives = 82/166 (49%), Gaps = 3/166 (1%)
Frame = +2
Query: 221 LQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEER 400
++KK+ ++ D ++ EQA D + E + E E+ +L +K++ E++L+K E
Sbjct: 4 IKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEA 63
Query: 401 SGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDAD---GKS 571
AQ+KL A++ A + L R Q EE +D+ +L A E+A+ GK
Sbjct: 64 LKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAELSEGKC 123
Query: 572 DEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLE 709
E+ +L V + L+ E + + K E E+KV+ + LK E
Sbjct: 124 AELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAE 169
Score = 53.2 bits (122), Expect = 9e-07
Identities = 40/144 (27%), Positives = 75/144 (52%), Gaps = 17/144 (11%)
Frame = +2
Query: 344 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 523
A+ +K+Q ++ D E + +R+ A+ A+ + + L+ + + E+ +D+ +
Sbjct: 3 AIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSE 62
Query: 524 QLKEARL---LAE----DADGKSDEVSRKLAFVEDELEVAEDRVKSG----------DAK 652
LK+A+ LAE DA+ ++R++ VE+EL+ A++R+ + + K
Sbjct: 63 ALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAELSEGK 122
Query: 653 ISXLEXELKVVGNSLKSLEVSEXK 724
+ LE ELK V N+LKSLE K
Sbjct: 123 CAELEEELKTVTNNLKSLEAQAEK 146
>DQ120714-1|ABC40673.1| 247|Homo sapiens rcTPM3 protein.
Length = 247
Score = 129 bits (312), Expect = 9e-30
Identities = 62/171 (36%), Positives = 115/171 (67%)
Frame = +2
Query: 212 VRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKS 391
+ +++K+ +++ + + E+ +++E + + EAEVA+LNR++Q +EE+L++
Sbjct: 6 IEAVKRKIQVLQQQADDAEERAERLQQEVEGERRARKQAEAEVASLNRRIQLVEEELDRP 65
Query: 392 EERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKS 571
+ER TA QKL EA+++A E+ R KV+ENRA +DEE+M+ QLKEA+ +AE+AD K
Sbjct: 66 QERLATALQKLEEAEKAAGESERGMKVIENRALKDEEKMELQELQLKEAKHIAEEADRKY 125
Query: 572 DEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXK 724
+EV+RKL +E +LE E+R + +++ ++ +++++ +LK L +E K
Sbjct: 126 EEVARKLVTIEGDLERTEERAELTESRCREMDEQIRLMDQNLKCLSAAEEK 176
Score = 73.3 bits (172), Expect = 8e-13
Identities = 49/216 (22%), Positives = 105/216 (48%), Gaps = 7/216 (3%)
Frame = +2
Query: 83 TMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 262
T++A+K+K+Q ++ + D+A ++A+ +Q+ ++ EV L +++ VEE+L
Sbjct: 5 TIEAVKRKIQVLQQQADDAEERAERLQQEVEGERRARKQAEAEVASLNRRIQLVEEELDR 64
Query: 263 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 442
+ +L A + LEE EK +E + + + + EE +E E + A+ EA +
Sbjct: 65 PQERLATALQKLEEAEKAAGESERGMKVIENRALKDEEKMELQELQLKEAKHIAEEADRK 124
Query: 443 ADENNRMCKVLENRAQQDEERMDQLTNQLKE----ARLLAED---ADGKSDEVSRKLAFV 601
+E R +E ++ EER + ++ +E RL+ ++ ++ S+K
Sbjct: 125 YEEVARKLVTIEGDLERTEERAELTESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKY 184
Query: 602 EDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLE 709
E+E+++ D+ K + E + + ++ LE
Sbjct: 185 EEEIKIFTDKPKEAETCAEFAERSVAKLEKTIDDLE 220
Score = 60.9 bits (141), Expect = 5e-09
Identities = 45/194 (23%), Positives = 99/194 (51%), Gaps = 7/194 (3%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
+Q A + ++ +++Q ++ E D ++ T Q+ +A A + ++ ++ + + E
Sbjct: 42 KQAEAEVASLNRRIQLVEEELDRPQERLATALQKLEEAEKAAGESERGMKVIENRALKDE 101
Query: 248 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 427
E + L + +L++A EE +++ EVA RK+ IE DLE++EER+ + +
Sbjct: 102 EKMELQELQLKEAKHIAEEADRKYE----EVA---RKLVTIEGDLERTEERAELTESRCR 154
Query: 428 EAQQS---ADENNRMCKVLENRAQQDEERMDQ----LTNQLKEARLLAEDADGKSDEVSR 586
E + D+N + E + Q E++ ++ T++ KEA AE A+ ++ +
Sbjct: 155 EMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKIFTDKPKEAETCAEFAERSVAKLEK 214
Query: 587 KLAFVEDELEVAED 628
+ +ED+L+ ++
Sbjct: 215 TIDDLEDKLKCTKE 228
>AL590431-5|CAH71263.1| 224|Homo sapiens tropomyosin 3 protein.
Length = 224
Score = 105 bits (252), Expect = 2e-22
Identities = 55/137 (40%), Positives = 90/137 (65%)
Frame = +2
Query: 314 QLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQ 493
Q A +AE A R +++E + E+R TA QKL EA+++ADE+ R KV+ENRA +
Sbjct: 18 QQQADDAEERA-ERLQREVEGERRAREQRLATALQKLEEAEKAADESERGMKVIENRALK 76
Query: 494 DEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXE 673
DEE+M+ QLKEA+ +AE+AD K +EV+RKL +E +LE E+R + +++ ++ +
Sbjct: 77 DEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQ 136
Query: 674 LKVVGNSLKSLEVSEXK 724
++++ +LK L +E K
Sbjct: 137 IRLMDQNLKCLSAAEEK 153
Score = 68.9 bits (161), Expect = 2e-11
Identities = 48/200 (24%), Positives = 105/200 (52%), Gaps = 18/200 (9%)
Frame = +2
Query: 83 TMDAIKKKMQAMKLEKDNAMDKADTC------EQQARDANL-----RAEKVNEEVRELQK 229
T++A+K+K+Q ++ + D+A ++A+ E++AR+ L + E+ + E ++
Sbjct: 6 TIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQRLATALQKLEEAEKAADESER 65
Query: 230 KLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGT 409
+ +E + ++ K+E L+E + + + + RK+ IE DLE++EER+
Sbjct: 66 GMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAEL 125
Query: 410 AQQKLLEAQQS---ADENNRMCKVLENRAQQDEERMDQ----LTNQLKEARLLAEDADGK 568
A+ + E + D+N + E + Q E++ ++ LT++LKEA AE A+
Sbjct: 126 AESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERS 185
Query: 569 SDEVSRKLAFVEDELEVAED 628
++ + + +ED+L+ ++
Sbjct: 186 VAKLEKTIDDLEDKLKCTKE 205
>AL590431-6|CAH71265.1| 232|Homo sapiens tropomyosin 3 protein.
Length = 232
Score = 99 bits (238), Expect = 8e-21
Identities = 53/171 (30%), Positives = 105/171 (61%)
Frame = +2
Query: 212 VRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKS 391
+ +++K+ +++ + + E+ +++E + + EAEVA+LNR++Q +EE+L+++
Sbjct: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
Query: 392 EERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKS 571
+ER TA QKL EA+++ADE ++M+ QLKEA+ +AE+AD K
Sbjct: 67 QERLATALQKLEEAEKAADE----------------KKMELQEIQLKEAKHIAEEADRKY 110
Query: 572 DEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXK 724
+EV+RKL +E +LE E+R + +++ ++ +++++ +LK L +E K
Sbjct: 111 EEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEK 161
Score = 79.0 bits (186), Expect = 2e-14
Identities = 45/206 (21%), Positives = 105/206 (50%)
Frame = +2
Query: 83 TMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 262
T++A+K+K+Q ++ + D+A ++A+ +++ E+ EV L +++ VEE+L
Sbjct: 6 TIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDR 65
Query: 263 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 442
+ +L A + LEE EK A E ++ ++++ + E+++ + +KL+ +
Sbjct: 66 AQERLATALQKLEEAEK--AADEKKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGD 123
Query: 443 ADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 622
+ ++ E+R ++ +E++ + LK E K D+ ++ + D+L+ A
Sbjct: 124 LERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKLKEA 183
Query: 623 EDRVKSGDAKISXLEXELKVVGNSLK 700
E R + + ++ LE + + + LK
Sbjct: 184 ETRAEFAERSVAKLEKTIDDLEDKLK 209
>AF186110-1|AAG17015.1| 227|Homo sapiens TPM4-ALK fusion
oncoprotein type 1 protein.
Length = 227
Score = 89.0 bits (211), Expect = 2e-17
Identities = 46/86 (53%), Positives = 61/86 (70%)
Frame = +2
Query: 467 KVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGD 646
KV+ENRA +DEE+M+ QLKEA+ +AE+AD K +EV+RKL +E ELE AE+R + +
Sbjct: 2 KVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAEERAEVSE 61
Query: 647 AKISXLEXELKVVGNSLKSLEVSEXK 724
K LE ELK V N+LKSLE + K
Sbjct: 62 LKCGDLEEELKNVTNNLKSLEAASEK 87
Score = 39.5 bits (88), Expect = 0.012
Identities = 29/133 (21%), Positives = 58/133 (43%), Gaps = 7/133 (5%)
Frame = +2
Query: 347 LNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMD----- 511
+ + + EE +E E + A+ EA + +E R +LE ++ EER +
Sbjct: 4 IENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAEERAEVSELK 63
Query: 512 --QLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVV 685
L +LK + + S++ S K E+E+++ D++K + + E + +
Sbjct: 64 CGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKL 123
Query: 686 GNSLKSLEVSEXK 724
++ LEV K
Sbjct: 124 EKTIDDLEVYRRK 136
>BC062740-1|AAH62740.1| 158|Homo sapiens TPM3 protein protein.
Length = 158
Score = 87.8 bits (208), Expect = 4e-17
Identities = 45/86 (52%), Positives = 61/86 (70%)
Frame = +2
Query: 467 KVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGD 646
KV+ENRA +DEE+M+ QLKEA+ +AE+AD K +EV+RKL +E +LE E+R + +
Sbjct: 2 KVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAE 61
Query: 647 AKISXLEXELKVVGNSLKSLEVSEXK 724
+K S LE ELK V N+LKSLE K
Sbjct: 62 SKCSELEEELKNVTNNLKSLEAQAEK 87
Score = 56.8 bits (131), Expect = 7e-08
Identities = 35/155 (22%), Positives = 75/155 (48%)
Frame = +2
Query: 242 VEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQK 421
+E + ++ K+E L+E + + + + RK+ IE DLE++EER+ A+ K
Sbjct: 4 IENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESK 63
Query: 422 LLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFV 601
E ++ K LE +A++ ++ D+ ++K ++A+ +++ R +A +
Sbjct: 64 CSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKL 123
Query: 602 EDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSL 706
E ++ ED + + K + EL N + S+
Sbjct: 124 EKTIDDLEDELYAQKLKYKAISEELDHALNDMTSI 158
Score = 36.3 bits (80), Expect = 0.11
Identities = 39/147 (26%), Positives = 66/147 (44%), Gaps = 1/147 (0%)
Frame = +2
Query: 203 NEEVRELQK-KLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEED 379
+EE ELQ+ +L + + K E+ + L E L TE K ++EE+
Sbjct: 11 DEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEE 70
Query: 380 LEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDA 559
L ++ T K LEAQ + + + EE + LT++LKEA AE A
Sbjct: 71 L-----KNVTNNLKSLEAQ---------AEKYSQKEDKYEEEIKILTDKLKEAETRAEFA 116
Query: 560 DGKSDEVSRKLAFVEDELEVAEDRVKS 640
+ ++ + + +EDEL + + K+
Sbjct: 117 ERSVAKLEKTIDDLEDELYAQKLKYKA 143
>AL590431-4|CAH71262.1| 158|Homo sapiens tropomyosin 3 protein.
Length = 158
Score = 87.8 bits (208), Expect = 4e-17
Identities = 45/86 (52%), Positives = 61/86 (70%)
Frame = +2
Query: 467 KVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGD 646
KV+ENRA +DEE+M+ QLKEA+ +AE+AD K +EV+RKL +E +LE E+R + +
Sbjct: 2 KVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAE 61
Query: 647 AKISXLEXELKVVGNSLKSLEVSEXK 724
+K S LE ELK V N+LKSLE K
Sbjct: 62 SKCSELEEELKNVTNNLKSLEAQAEK 87
Score = 56.8 bits (131), Expect = 7e-08
Identities = 35/155 (22%), Positives = 75/155 (48%)
Frame = +2
Query: 242 VEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQK 421
+E + ++ K+E L+E + + + + RK+ IE DLE++EER+ A+ K
Sbjct: 4 IENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESK 63
Query: 422 LLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFV 601
E ++ K LE +A++ ++ D+ ++K ++A+ +++ R +A +
Sbjct: 64 CSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKL 123
Query: 602 EDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSL 706
E ++ ED + + K + EL N + S+
Sbjct: 124 EKTIDDLEDELYAQKLKYKAISEELDHALNDMTSI 158
Score = 36.3 bits (80), Expect = 0.11
Identities = 39/147 (26%), Positives = 66/147 (44%), Gaps = 1/147 (0%)
Frame = +2
Query: 203 NEEVRELQK-KLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEED 379
+EE ELQ+ +L + + K E+ + L E L TE K ++EE+
Sbjct: 11 DEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEE 70
Query: 380 LEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDA 559
L ++ T K LEAQ + + + EE + LT++LKEA AE A
Sbjct: 71 L-----KNVTNNLKSLEAQ---------AEKYSQKEDKYEEEIKILTDKLKEAETRAEFA 116
Query: 560 DGKSDEVSRKLAFVEDELEVAEDRVKS 640
+ ++ + + +EDEL + + K+
Sbjct: 117 ERSVAKLEKTIDDLEDELYAQKLKYKA 143
>AL590431-3|CAH71261.1| 158|Homo sapiens tropomyosin 3 protein.
Length = 158
Score = 87.8 bits (208), Expect = 4e-17
Identities = 45/86 (52%), Positives = 61/86 (70%)
Frame = +2
Query: 467 KVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGD 646
KV+ENRA +DEE+M+ QLKEA+ +AE+AD K +EV+RKL +E +LE E+R + +
Sbjct: 2 KVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAE 61
Query: 647 AKISXLEXELKVVGNSLKSLEVSEXK 724
+K S LE ELK V N+LKSLE K
Sbjct: 62 SKCSELEEELKNVTNNLKSLEAQAEK 87
Score = 54.0 bits (124), Expect = 5e-07
Identities = 31/132 (23%), Positives = 68/132 (51%)
Frame = +2
Query: 242 VEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQK 421
+E + ++ K+E L+E + + + + RK+ IE DLE++EER+ A+ K
Sbjct: 4 IENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESK 63
Query: 422 LLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFV 601
E ++ K LE +A++ ++ D+ ++K ++A+ +++ R +A +
Sbjct: 64 CSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKL 123
Query: 602 EDELEVAEDRVK 637
E ++ ED++K
Sbjct: 124 EKTIDDLEDKLK 135
Score = 35.5 bits (78), Expect = 0.20
Identities = 37/143 (25%), Positives = 65/143 (45%), Gaps = 1/143 (0%)
Frame = +2
Query: 203 NEEVRELQK-KLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEED 379
+EE ELQ+ +L + + K E+ + L E L TE K ++EE+
Sbjct: 11 DEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEE 70
Query: 380 LEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDA 559
L ++ T K LEAQ + + + EE + LT++LKEA AE A
Sbjct: 71 L-----KNVTNNLKSLEAQ---------AEKYSQKEDKYEEEIKILTDKLKEAETRAEFA 116
Query: 560 DGKSDEVSRKLAFVEDELEVAED 628
+ ++ + + +ED+L+ ++
Sbjct: 117 ERSVAKLEKTIDDLEDKLKCTKE 139
>BX537964-1|CAD97928.1| 898|Homo sapiens hypothetical protein
protein.
Length = 898
Score = 66.1 bits (154), Expect = 1e-10
Identities = 56/224 (25%), Positives = 97/224 (43%), Gaps = 5/224 (2%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
++ A M+ KK + + EK+ + K E+++ D LR EK L+KKL
Sbjct: 288 KEMAQRMEQANKKCEEARQEKEAMVMKYVRGEKESLD--LRKEK-----ETLEKKLRDAN 340
Query: 248 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 427
++L N NK++Q +++ + E E L R++ +++ED+ + AQ KL
Sbjct: 341 KELEKNTNKIKQLSQEKGRLHQLYETKEGETTRLIREIDKLKEDINSHVIKVKWAQNKLK 400
Query: 428 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKE-ARLLAEDADGKSDEVSRKLAFVE 604
S E K + Q +E DQ+ ++ + E + KS+E+ KL +
Sbjct: 401 AEMDSHKETKDKLKETTTKLTQAKEEADQIRKNCQDMIKTYQESEEIKSNELDAKLRVTK 460
Query: 605 DELE----VAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXK 724
ELE D+++ AKI LE + + L K
Sbjct: 461 GELEKQMQEKSDQLEMHHAKIKELEDLKRTFKEGMDELRTLRTK 504
Score = 39.1 bits (87), Expect = 0.016
Identities = 39/217 (17%), Positives = 90/217 (41%), Gaps = 15/217 (6%)
Frame = +2
Query: 104 KMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQ 283
K++ + EK +T E + +K+ E++ K+ + L + ++
Sbjct: 349 KIKQLSQEKGRLHQLYETKEGETTRLIREIDKLKEDINSHVIKVKWAQNKLKAEMDSHKE 408
Query: 284 ANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEE------------RSGTAQQKLL 427
L+E +LT + E + + Q + + ++SEE G ++++
Sbjct: 409 TKDKLKETTTKLTQAKEEADQIRKNCQDMIKTYQESEEIKSNELDAKLRVTKGELEKQMQ 468
Query: 428 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFV-- 601
E + ++ K LE+ + +E MD+L + + L ++ DE+S+ +
Sbjct: 469 EKSDQLEMHHAKIKELEDLKRTFKEGMDELRTLRTKVKCLEDERLRTEDELSKYKEIINR 528
Query: 602 -EDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLE 709
+ E++ D+VK+ D L+ + + N + +E
Sbjct: 529 QKAEIQNLLDKVKTADQLQEQLQRGKQEIENLKEEVE 565
>BC105632-1|AAI05633.1| 898|Homo sapiens chromosome 10 open reading
frame 118 protein.
Length = 898
Score = 66.1 bits (154), Expect = 1e-10
Identities = 56/224 (25%), Positives = 97/224 (43%), Gaps = 5/224 (2%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
++ A M+ KK + + EK+ + K E+++ D LR EK L+KKL
Sbjct: 288 KEMAQRMEQANKKCEEARQEKEAMVMKYVRGEKESLD--LRKEK-----ETLEKKLRDAN 340
Query: 248 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 427
++L N NK++Q +++ + E E L R++ +++ED+ + AQ KL
Sbjct: 341 KELEKNTNKIKQLSQEKGRLHQLYETKEGETTRLIREIDKLKEDINSHVIKVKWAQNKLK 400
Query: 428 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKE-ARLLAEDADGKSDEVSRKLAFVE 604
S E K + Q +E DQ+ ++ + E + KS+E+ KL +
Sbjct: 401 AEMDSHKETKDKLKETTTKLTQAKEEADQIRKNCQDMIKTYQESEEIKSNELDAKLRVTK 460
Query: 605 DELE----VAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXK 724
ELE D+++ AKI LE + + L K
Sbjct: 461 GELEKQMQEKSDQLEMHHAKIKELEDLKRTFKEGMDELRTLRTK 504
Score = 39.1 bits (87), Expect = 0.016
Identities = 39/217 (17%), Positives = 90/217 (41%), Gaps = 15/217 (6%)
Frame = +2
Query: 104 KMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQ 283
K++ + EK +T E + +K+ E++ K+ + L + ++
Sbjct: 349 KIKQLSQEKGRLHQLYETKEGETTRLIREIDKLKEDINSHVIKVKWAQNKLKAEMDSHKE 408
Query: 284 ANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEE------------RSGTAQQKLL 427
L+E +LT + E + + Q + + ++SEE G ++++
Sbjct: 409 TKDKLKETTTKLTQAKEEADQIRKNCQDMIKTYQESEEIKSNELDAKLRVTKGELEKQMQ 468
Query: 428 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFV-- 601
E + ++ K LE+ + +E MD+L + + L ++ DE+S+ +
Sbjct: 469 EKSDQLEMHHAKIKELEDLKRTFKEGMDELRTLRTKVKCLEDERLRTEDELSKYKEIINR 528
Query: 602 -EDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLE 709
+ E++ D+VK+ D L+ + + N + +E
Sbjct: 529 QKAEIQNLLDKVKTADQLQEQLQRGKQEIENLKEEVE 565
>BC103499-1|AAI03500.1| 898|Homo sapiens chromosome 10 open reading
frame 118 protein.
Length = 898
Score = 66.1 bits (154), Expect = 1e-10
Identities = 56/224 (25%), Positives = 97/224 (43%), Gaps = 5/224 (2%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
++ A M+ KK + + EK+ + K E+++ D LR EK L+KKL
Sbjct: 288 KEMAQRMEQANKKCEEARQEKEAMVMKYVRGEKESLD--LRKEK-----ETLEKKLRDAN 340
Query: 248 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 427
++L N NK++Q +++ + E E L R++ +++ED+ + AQ KL
Sbjct: 341 KELEKNTNKIKQLSQEKGRLHQLYETKEGETTRLIREIDKLKEDINSHVIKVKWAQNKLK 400
Query: 428 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKE-ARLLAEDADGKSDEVSRKLAFVE 604
S E K + Q +E DQ+ ++ + E + KS+E+ KL +
Sbjct: 401 AEMDSHKETKDKLKETTTKLTQAKEEADQIRKNCQDMIKTYQESEEIKSNELDAKLRVTK 460
Query: 605 DELE----VAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXK 724
ELE D+++ AKI LE + + L K
Sbjct: 461 GELEKQMQEKSDQLEMHHAKIKELEDLKRTFKEGMDELRTLRTK 504
Score = 39.1 bits (87), Expect = 0.016
Identities = 39/217 (17%), Positives = 90/217 (41%), Gaps = 15/217 (6%)
Frame = +2
Query: 104 KMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQ 283
K++ + EK +T E + +K+ E++ K+ + L + ++
Sbjct: 349 KIKQLSQEKGRLHQLYETKEGETTRLIREIDKLKEDINSHVIKVKWAQNKLKAEMDSHKE 408
Query: 284 ANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEE------------RSGTAQQKLL 427
L+E +LT + E + + Q + + ++SEE G ++++
Sbjct: 409 TKDKLKETTTKLTQAKEEADQIRKNCQDMIKTYQESEEIKSNELDAKLRVTKGELEKQMQ 468
Query: 428 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFV-- 601
E + ++ K LE+ + +E MD+L + + L ++ DE+S+ +
Sbjct: 469 EKSDQLEMHHAKIKELEDLKRTFKEGMDELRTLRTKVKCLEDERLRTEDELSKYKEIINR 528
Query: 602 -EDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLE 709
+ E++ D+VK+ D L+ + + N + +E
Sbjct: 529 QKAEIQNLLDKVKTADQLQEQLQRGKQEIENLKEEVE 565
>BC100670-1|AAI00671.1| 1004|Homo sapiens C10orf118 protein protein.
Length = 1004
Score = 66.1 bits (154), Expect = 1e-10
Identities = 56/224 (25%), Positives = 97/224 (43%), Gaps = 5/224 (2%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
++ A M+ KK + + EK+ + K E+++ D LR EK L+KKL
Sbjct: 394 KEMAQRMEQANKKCEEARQEKEAMVMKYVRGEKESLD--LRKEK-----ETLEKKLRDAN 446
Query: 248 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 427
++L N NK++Q +++ + E E L R++ +++ED+ + AQ KL
Sbjct: 447 KELEKNTNKIKQLSQEKGRLHQLYETKEGETTRLIREIDKLKEDINSHVIKVKWAQNKLK 506
Query: 428 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKE-ARLLAEDADGKSDEVSRKLAFVE 604
S E K + Q +E DQ+ ++ + E + KS+E+ KL +
Sbjct: 507 AEMDSHKETKDKLKETTTKLTQAKEEADQIRKNCQDMIKTYQESEEIKSNELDAKLRVTK 566
Query: 605 DELE----VAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXK 724
ELE D+++ AKI LE + + L K
Sbjct: 567 GELEKQMQEKSDQLEMHHAKIKELEDLKRTFKEGMDELRTLRTK 610
Score = 39.1 bits (87), Expect = 0.016
Identities = 39/217 (17%), Positives = 90/217 (41%), Gaps = 15/217 (6%)
Frame = +2
Query: 104 KMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQ 283
K++ + EK +T E + +K+ E++ K+ + L + ++
Sbjct: 455 KIKQLSQEKGRLHQLYETKEGETTRLIREIDKLKEDINSHVIKVKWAQNKLKAEMDSHKE 514
Query: 284 ANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEE------------RSGTAQQKLL 427
L+E +LT + E + + Q + + ++SEE G ++++
Sbjct: 515 TKDKLKETTTKLTQAKEEADQIRKNCQDMIKTYQESEEIKSNELDAKLRVTKGELEKQMQ 574
Query: 428 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFV-- 601
E + ++ K LE+ + +E MD+L + + L ++ DE+S+ +
Sbjct: 575 EKSDQLEMHHAKIKELEDLKRTFKEGMDELRTLRTKVKCLEDERLRTEDELSKYKEIINR 634
Query: 602 -EDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLE 709
+ E++ D+VK+ D L+ + + N + +E
Sbjct: 635 QKAEIQNLLDKVKTADQLQEQLQRGKQEIENLKEEVE 671
>AK092712-1|BAC03956.1| 183|Homo sapiens protein ( Homo sapiens
cDNA FLJ35393 fis, clone SKNSH2000971, highly similar to
TROPOMYOSIN, CYTOSKELETAL TYPE. ).
Length = 183
Score = 66.1 bits (154), Expect = 1e-10
Identities = 31/104 (29%), Positives = 64/104 (61%)
Frame = +2
Query: 413 QQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKL 592
++K+ QQ AD+ + L+ + ++ + ++ QLKEA+ +AE+AD K +EV+RKL
Sbjct: 11 KRKIQVLQQQADDAEERAERLQREVEGEKMELQEI--QLKEAKHIAEEADRKYEEVARKL 68
Query: 593 AFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXK 724
+E +LE E+R + +++ ++ +++++ +LK L +E K
Sbjct: 69 VIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEK 112
Score = 57.6 bits (133), Expect = 4e-08
Identities = 48/168 (28%), Positives = 87/168 (51%), Gaps = 7/168 (4%)
Frame = +2
Query: 146 KADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTA 325
K +QQA DA RAE++ EV + +L +++ L++A EE +++
Sbjct: 13 KIQVLQQQADDAEERAERLQREVEGEKMELQEIQ---------LKEAKHIAEEADRKYE- 62
Query: 326 TEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS---ADENNRMCKVLENRAQQD 496
EVA RK+ IE DLE++EER+ A+ + E + D+N + E + Q
Sbjct: 63 ---EVA---RKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQK 116
Query: 497 EERMDQ----LTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAED 628
E++ ++ LT++LKEA AE A+ ++ + + +ED+L+ ++
Sbjct: 117 EDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDKLKCTKE 164
>AF273054-1|AAM44457.1| 613|Homo sapiens CTCL tumor antigen
HD-CL-01 protein.
Length = 613
Score = 66.1 bits (154), Expect = 1e-10
Identities = 56/224 (25%), Positives = 97/224 (43%), Gaps = 5/224 (2%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
++ A M+ KK + + EK+ + K E+++ D LR EK L+KKL
Sbjct: 105 KEMAQRMEQANKKCEEARQEKEAMVMKYVRGEKESLD--LRKEK-----ETLEKKLRDAN 157
Query: 248 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 427
++L N NK++Q +++ + E E L R++ +++ED+ + AQ KL
Sbjct: 158 KELEKNTNKIKQLSQEKGRLHQLYETKEGETTRLIREIDKLKEDINSHVIKVKWAQNKLK 217
Query: 428 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKE-ARLLAEDADGKSDEVSRKLAFVE 604
S E K + Q +E DQ+ ++ + E + KS+E+ KL +
Sbjct: 218 AEMDSHKETKDKLKETTTKLTQAKEEADQIRKNCQDMIKTYQESEEIKSNELDAKLRVTK 277
Query: 605 DELE----VAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXK 724
ELE D+++ AKI LE + + L K
Sbjct: 278 GELEKQMQEKSDQLEMHHAKIKELEDLKRTFKEGMDELRTLRTK 321
Score = 39.1 bits (87), Expect = 0.016
Identities = 39/217 (17%), Positives = 90/217 (41%), Gaps = 15/217 (6%)
Frame = +2
Query: 104 KMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQ 283
K++ + EK +T E + +K+ E++ K+ + L + ++
Sbjct: 166 KIKQLSQEKGRLHQLYETKEGETTRLIREIDKLKEDINSHVIKVKWAQNKLKAEMDSHKE 225
Query: 284 ANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEE------------RSGTAQQKLL 427
L+E +LT + E + + Q + + ++SEE G ++++
Sbjct: 226 TKDKLKETTTKLTQAKEEADQIRKNCQDMIKTYQESEEIKSNELDAKLRVTKGELEKQMQ 285
Query: 428 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFV-- 601
E + ++ K LE+ + +E MD+L + + L ++ DE+S+ +
Sbjct: 286 EKSDQLEMHHAKIKELEDLKRTFKEGMDELRTLRTKVKCLEDERLRTEDELSKYKEIINR 345
Query: 602 -EDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLE 709
+ E++ D+VK+ D L+ + + N + +E
Sbjct: 346 QKAEIQNLLDKVKTADQLQEQLQRGKQEIENLKEEVE 382
>S73840-1|AAC13916.1| 231|Homo sapiens type IIA myosin heavy chain
protein.
Length = 231
Score = 62.5 bits (145), Expect = 2e-09
Identities = 48/214 (22%), Positives = 108/214 (50%), Gaps = 5/214 (2%)
Frame = +2
Query: 83 TMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 262
T ++ + M+ E ++ + +A E++A+ A A + EE+++ Q A +E +
Sbjct: 22 TKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLER---M 78
Query: 263 NKNKLEQANKDL-----EEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 427
KN +EQ KDL E ++ L + ++ L +V+++E ++E ++R+ A + L
Sbjct: 79 KKN-MEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLR 137
Query: 428 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 607
+ ++ E + + ++ +D+L ++K + AE+A+ +S+ K ++
Sbjct: 138 KHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQH 197
Query: 608 ELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLE 709
ELE AE+R +++++ L + + V + S E
Sbjct: 198 ELEEAEERADIAESQVNKLRVKSREVHTKVISEE 231
>BC126409-1|AAI26410.1| 1941|Homo sapiens myosin, heavy chain 2,
skeletal muscle, adult protein.
Length = 1941
Score = 62.5 bits (145), Expect = 2e-09
Identities = 48/214 (22%), Positives = 108/214 (50%), Gaps = 5/214 (2%)
Frame = +2
Query: 83 TMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 262
T ++ + M+ E ++ + +A E++A+ A A + EE+++ Q A +E +
Sbjct: 1732 TKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLER---M 1788
Query: 263 NKNKLEQANKDL-----EEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 427
KN +EQ KDL E ++ L + ++ L +V+++E ++E ++R+ A + L
Sbjct: 1789 KKN-MEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLR 1847
Query: 428 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 607
+ ++ E + + ++ +D+L ++K + AE+A+ +S+ K ++
Sbjct: 1848 KHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQH 1907
Query: 608 ELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLE 709
ELE AE+R +++++ L + + V + S E
Sbjct: 1908 ELEEAEERADIAESQVNKLRVKSREVHTKVISEE 1941
Score = 55.2 bits (127), Expect = 2e-07
Identities = 47/212 (22%), Positives = 101/212 (47%), Gaps = 7/212 (3%)
Frame = +2
Query: 95 IKKKMQA---MKLEKDNAMDKAD-TCEQQARDANLRAE--KVNEEVRELQKKLAQVEEDL 256
IK K+Q +K + A D+ + E A+ L E ++ +++ +L+ LA+VE++
Sbjct: 915 IKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEK 974
Query: 257 ILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQ 436
+NK++ +++ ++ + E AL QQ +DL+ E++ T + ++ +
Sbjct: 975 HATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLE 1034
Query: 437 QSADENNRMCKVLENRAQQDEERMD-QLTNQLKEARLLAEDADGKSDEVSRKLAFVEDEL 613
Q D+ + E + + D ER +L LK A+ D + + ++ KL E E+
Sbjct: 1035 QQVDDLEGSLE-QEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEI 1093
Query: 614 EVAEDRVKSGDAKISXLEXELKVVGNSLKSLE 709
+ +++ A L+ ++K + ++ LE
Sbjct: 1094 SNLQSKIEDEQALGIQLQKKIKELQARIEELE 1125
Score = 46.4 bits (105), Expect = 1e-04
Identities = 32/134 (23%), Positives = 63/134 (47%), Gaps = 7/134 (5%)
Frame = +2
Query: 326 TEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEER 505
TE E+A + + Q+I+++L KSE + ++K++ + ++ + EER
Sbjct: 851 TEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEER 910
Query: 506 MDQLTN-------QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXL 664
DQL ++KE AED + + E++ K +EDE + + + ++ +
Sbjct: 911 CDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKV 970
Query: 665 EXELKVVGNSLKSL 706
E E N +K+L
Sbjct: 971 EKEKHATENKVKNL 984
Score = 38.7 bits (86), Expect = 0.021
Identities = 43/207 (20%), Positives = 87/207 (42%), Gaps = 10/207 (4%)
Frame = +2
Query: 119 KLEKDNAMDKADTCEQQA--RDANLRAEKVNEEVRELQKKLAQVEEDL---ILNKN-KLE 280
+LEK + + CE QA +A E ++ +Q +L QV+ ++ I K+ +++
Sbjct: 1531 ELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEID 1590
Query: 281 QANKD-LEEKEKQLTATEAEVAALN---RKVQQIEEDLEKSEERSGTAQQKLLEAQQSAD 448
Q ++ + E + +AE+ + N R +++E DL + E + A + EA ++
Sbjct: 1591 QLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYR 1650
Query: 449 ENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAED 628
+ K + + L QL A + +E+ L E ++AE
Sbjct: 1651 NTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQ 1710
Query: 629 RVKSGDAKISXLEXELKVVGNSLKSLE 709
+ ++ L + + N+ K LE
Sbjct: 1711 ELLDASERVQLLHTQNTSLINTKKKLE 1737
Score = 35.9 bits (79), Expect = 0.15
Identities = 47/215 (21%), Positives = 102/215 (47%), Gaps = 1/215 (0%)
Frame = +2
Query: 86 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 265
MD +K Q + K + ++ + + D ++ ++++ELQ ++ ++EE++
Sbjct: 1073 MDIENEKQQLDEKLKKKEFEISNL-QSKIEDEQALGIQLQKKIKELQARIEELEEEI--- 1128
Query: 266 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 445
+ E+A++ EK++ + L+R++++I E LE E T+ Q + ++ A
Sbjct: 1129 --EAERASRAKAEKQR---------SDLSRELEEISERLE--EAGGATSAQIEMNKKREA 1175
Query: 446 DENNRMCKVLENRAQQDEERMDQLTNQLKEA-RLLAEDADGKSDEVSRKLAFVEDELEVA 622
E +M + LE Q E L + ++ L E D V +KL + E+++
Sbjct: 1176 -EFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQID-NLQRVKQKLEKEKSEMKME 1233
Query: 623 EDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXKA 727
D + S +S + L+ + +L+ ++SE K+
Sbjct: 1234 IDDLASNVETVSKAKGNLEKMCRTLED-QLSELKS 1267
>AF111784-1|AAD29950.1| 1941|Homo sapiens myosin heavy chain IIa
protein.
Length = 1941
Score = 62.5 bits (145), Expect = 2e-09
Identities = 48/214 (22%), Positives = 108/214 (50%), Gaps = 5/214 (2%)
Frame = +2
Query: 83 TMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 262
T ++ + M+ E ++ + +A E++A+ A A + EE+++ Q A +E +
Sbjct: 1732 TKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLER---M 1788
Query: 263 NKNKLEQANKDL-----EEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 427
KN +EQ KDL E ++ L + ++ L +V+++E ++E ++R+ A + L
Sbjct: 1789 KKN-MEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLR 1847
Query: 428 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 607
+ ++ E + + ++ +D+L ++K + AE+A+ +S+ K ++
Sbjct: 1848 KHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQH 1907
Query: 608 ELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLE 709
ELE AE+R +++++ L + + V + S E
Sbjct: 1908 ELEEAEERADIAESQVNKLRVKSREVHTKVISEE 1941
Score = 55.2 bits (127), Expect = 2e-07
Identities = 47/212 (22%), Positives = 101/212 (47%), Gaps = 7/212 (3%)
Frame = +2
Query: 95 IKKKMQA---MKLEKDNAMDKAD-TCEQQARDANLRAE--KVNEEVRELQKKLAQVEEDL 256
IK K+Q +K + A D+ + E A+ L E ++ +++ +L+ LA+VE++
Sbjct: 915 IKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEK 974
Query: 257 ILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQ 436
+NK++ +++ ++ + E AL QQ +DL+ E++ T + ++ +
Sbjct: 975 HATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLE 1034
Query: 437 QSADENNRMCKVLENRAQQDEERMD-QLTNQLKEARLLAEDADGKSDEVSRKLAFVEDEL 613
Q D+ + E + + D ER +L LK A+ D + + ++ KL E E+
Sbjct: 1035 QQVDDLEGSLE-QEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEI 1093
Query: 614 EVAEDRVKSGDAKISXLEXELKVVGNSLKSLE 709
+ +++ A L+ ++K + ++ LE
Sbjct: 1094 SNLQSKIEDEQALGIQLQKKIKELQARIEELE 1125
Score = 46.4 bits (105), Expect = 1e-04
Identities = 32/134 (23%), Positives = 63/134 (47%), Gaps = 7/134 (5%)
Frame = +2
Query: 326 TEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEER 505
TE E+A + + Q+I+++L KSE + ++K++ + ++ + EER
Sbjct: 851 TEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEER 910
Query: 506 MDQLTN-------QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXL 664
DQL ++KE AED + + E++ K +EDE + + + ++ +
Sbjct: 911 CDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKV 970
Query: 665 EXELKVVGNSLKSL 706
E E N +K+L
Sbjct: 971 EKEKHATENKVKNL 984
Score = 38.7 bits (86), Expect = 0.021
Identities = 43/207 (20%), Positives = 87/207 (42%), Gaps = 10/207 (4%)
Frame = +2
Query: 119 KLEKDNAMDKADTCEQQA--RDANLRAEKVNEEVRELQKKLAQVEEDL---ILNKN-KLE 280
+LEK + + CE QA +A E ++ +Q +L QV+ ++ I K+ +++
Sbjct: 1531 ELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEID 1590
Query: 281 QANKD-LEEKEKQLTATEAEVAALN---RKVQQIEEDLEKSEERSGTAQQKLLEAQQSAD 448
Q ++ + E + +AE+ + N R +++E DL + E + A + EA ++
Sbjct: 1591 QLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYR 1650
Query: 449 ENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAED 628
+ K + + L QL A + +E+ L E ++AE
Sbjct: 1651 NTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQ 1710
Query: 629 RVKSGDAKISXLEXELKVVGNSLKSLE 709
+ ++ L + + N+ K LE
Sbjct: 1711 ELLDASERVQLLHTQNTSLINTKKKLE 1737
Score = 35.9 bits (79), Expect = 0.15
Identities = 47/215 (21%), Positives = 102/215 (47%), Gaps = 1/215 (0%)
Frame = +2
Query: 86 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 265
MD +K Q + K + ++ + + D ++ ++++ELQ ++ ++EE++
Sbjct: 1073 MDIENEKQQLDEKLKKKEFEISNL-QSKIEDEQALGIQLQKKIKELQARIEELEEEI--- 1128
Query: 266 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 445
+ E+A++ EK++ + L+R++++I E LE E T+ Q + ++ A
Sbjct: 1129 --EAERASRAKAEKQR---------SDLSRELEEISERLE--EAGGATSAQIEMNKKREA 1175
Query: 446 DENNRMCKVLENRAQQDEERMDQLTNQLKEA-RLLAEDADGKSDEVSRKLAFVEDELEVA 622
E +M + LE Q E L + ++ L E D V +KL + E+++
Sbjct: 1176 -EFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQID-NLQRVKQKLEKEKSEMKME 1233
Query: 623 EDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXKA 727
D + S +S + L+ + +L+ ++SE K+
Sbjct: 1234 IDDLASNVETVSKAKGNLEKMCRTLED-QLSELKS 1267
>M12126-1|AAA61229.1| 131|Homo sapiens TPM2 protein.
Length = 131
Score = 62.1 bits (144), Expect = 2e-09
Identities = 30/60 (50%), Positives = 42/60 (70%)
Frame = +2
Query: 545 LAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXK 724
+AED+D K +EV+RKL +E ELE +E+R + ++K LE ELK+V N+LKSLE K
Sbjct: 1 IAEDSDRKYEEVARKLVILEGELERSEERAEVAESKCGDLEEELKIVTNNLKSLEAQADK 60
Score = 41.1 bits (92), Expect = 0.004
Identities = 38/125 (30%), Positives = 60/125 (48%), Gaps = 7/125 (5%)
Frame = +2
Query: 353 RKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRA-----QQD--EERMD 511
RK+ +E +LE+SEER+ A+ K + ++ K LE +A ++D EE +
Sbjct: 14 RKLVILEGELERSEERAEVAESKCGDLEEELKIVTNNLKSLEAQADKYSTKEDKYEEEIK 73
Query: 512 QLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGN 691
L +LKEA AE A+ R +A +E ++ ED V + K + EL N
Sbjct: 74 LLEEKLKEAETRAEFAE-------RSVAKLEKTIDDLEDEVYAQKMKYKAISEELDNALN 126
Query: 692 SLKSL 706
+ SL
Sbjct: 127 DITSL 131
Score = 36.7 bits (81), Expect = 0.086
Identities = 25/123 (20%), Positives = 60/123 (48%)
Frame = +2
Query: 170 ARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAAL 349
A D++ + E+V ++ L+ +L + EE + ++K ++L+ L + EA+
Sbjct: 2 AEDSDRKYEEVARKLVILEGELERSEERAEVAESKCGDLEEELKIVTNNLKSLEAQADKY 61
Query: 350 NRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQL 529
+ K + EE+++ EE+ A+ + A++S + + LE+ + + ++ +L
Sbjct: 62 STKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEDEVYAQKMKYKAISEEL 121
Query: 530 KEA 538
A
Sbjct: 122 DNA 124
>X03740-1|CAA27380.1| 876|Homo sapiens protein ( Human skeletal mRNA
for myosin heavy chain light meromyosin region. ).
Length = 876
Score = 61.7 bits (143), Expect = 3e-09
Identities = 49/216 (22%), Positives = 111/216 (51%), Gaps = 7/216 (3%)
Frame = +2
Query: 83 TMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 262
T ++ + ++ E ++ + +A E++A+ A A + EE+++ Q A +E +
Sbjct: 667 TKKKLETDISQIQGEMEDIIKEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLER---M 723
Query: 263 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 442
KN LEQ KDL+ + + A + + +++Q++E + + E + Q++ +EA +
Sbjct: 724 KKN-LEQTVKDLQHRLDE--AEQLALKGGKKQIQKLEAKVRELEGEVESEQKRNVEAVKG 780
Query: 443 ADENNRMCKVLENRAQQD-------EERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFV 601
++ R K L + ++D ++ +D+L ++K + AE+A+ +S+ K +
Sbjct: 781 LHKHERKVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNVNLSKFRRI 840
Query: 602 EDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLE 709
+ ELE AE+R +++++ L + + V + S E
Sbjct: 841 QHELEEAEERADIAESQVNKLRVKSREVHTKIISEE 876
Score = 37.1 bits (82), Expect = 0.065
Identities = 36/224 (16%), Positives = 99/224 (44%), Gaps = 4/224 (1%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
Q+K+ A+++ +++ E+ + Q + + + + +EE+ ++++ ++E
Sbjct: 476 QEKSELQAALEEAEASLEHEEGKILRIQLEVNQVKSEVDRKIAEKDEEIDQMKRNHIRIE 535
Query: 248 EDLILNKNKLEQANKD---LEEK-EKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQ 415
E + N ++ D L++K E L E ++ NR + + + ++ Q
Sbjct: 536 ESMQSTLNAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEDLRNYQNTQAILKDTQ 595
Query: 416 QKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLA 595
L +A +S ++ ++E RA + +++L L++ + A+ + + S ++
Sbjct: 596 LHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQ 655
Query: 596 FVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXKA 727
+ + + K + IS ++ E++ + ++ E KA
Sbjct: 656 LLHTQNTSLINTKKKLETDISQIQGEMEDIIKEARNAEEKAKKA 699
Score = 31.9 bits (69), Expect = 2.4
Identities = 46/216 (21%), Positives = 97/216 (44%), Gaps = 1/216 (0%)
Frame = +2
Query: 80 ATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLI 259
+ MD K Q + K + + + + D ++ ++++ELQ ++ ++EE++
Sbjct: 6 SAMDIENDKQQLDEKLKKKEFEMSGL-QSKIEDEQALGMQLQKKIKELQARIEELEEEI- 63
Query: 260 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 439
+A + K ++L + L+R++++I E LE E T+ Q + ++
Sbjct: 64 -------EAERTSRAKAEKLRSD------LSRELEEISERLE--EAVGATSTQIEMNKKR 108
Query: 440 SADENNRMCKVLENRAQQDEERMDQLTNQLKEA-RLLAEDADGKSDEVSRKLAFVEDELE 616
A E +M + LE Q E L + ++ L E D V +KL + E++
Sbjct: 109 EA-EFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQID-NLQRVKQKLEKEKSEMK 166
Query: 617 VAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXK 724
+ D + S +S + L+ + +L+ ++SE K
Sbjct: 167 MEIDDLASNMETVSKAKGNLEKMCRALED-QLSEIK 201
>Z38133-1|CAA86293.1| 1937|Homo sapiens Myosin protein.
Length = 1937
Score = 61.3 bits (142), Expect = 3e-09
Identities = 45/212 (21%), Positives = 106/212 (50%), Gaps = 5/212 (2%)
Frame = +2
Query: 83 TMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 262
T ++ + ++ E + + ++ E++A+ A A + EE+++ Q A +E +
Sbjct: 1729 TKKKLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLER---M 1785
Query: 263 NKNKLEQANKDL-----EEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 427
KN LEQ KDL E ++ L + ++ L +V+++E ++E ++R+ A + L
Sbjct: 1786 KKN-LEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLR 1844
Query: 428 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 607
+ ++ E + + ++ +D+L ++K + AE+A+ +S+ K ++
Sbjct: 1845 KHERRVKELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLSKFRKLQH 1904
Query: 608 ELEVAEDRVKSGDAKISXLEXELKVVGNSLKS 703
ELE AE+R +++++ L + + V + +
Sbjct: 1905 ELEEAEERAHIAESQVNKLRVKSREVHTKISA 1936
Score = 52.8 bits (121), Expect = 1e-06
Identities = 55/221 (24%), Positives = 98/221 (44%), Gaps = 7/221 (3%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
+++ +A+ +Q+ + + D ++ + ++ + K N EV + + K E
Sbjct: 1323 EEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKY---E 1379
Query: 248 EDLILNKNKLEQANKDL----EEKEKQLTATEAEVAALNRKVQQIE---EDLEKSEERSG 406
D I +LE+A K L +E E+ + A A+ A+L + Q+++ EDL ERS
Sbjct: 1380 TDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSN 1439
Query: 407 TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSR 586
A L + Q++ D KVL Q+ EE +L KE+R L+ + +
Sbjct: 1440 AACAALDKKQRNFD------KVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEE 1493
Query: 587 KLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLE 709
L D+LE K+ +IS L ++ G + LE
Sbjct: 1494 SL----DQLETLRRENKNLQQEISDLTEQIAEGGKQIHELE 1530
Score = 52.4 bits (120), Expect = 2e-06
Identities = 52/219 (23%), Positives = 102/219 (46%), Gaps = 16/219 (7%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQA-MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQV 244
++K T+ K +Q ++ E D+ D + CEQ ++ ++ E +EV E ++ ++
Sbjct: 877 EEKMVTLLKEKNDLQLQVQSEADSLADAEERCEQLIKN-KIQLEAKIKEVTERAEEEEEI 935
Query: 245 EEDLILNKNKLE----QANKDLEEKE-------KQLTATEAEVAALNRKVQQIEEDLEK- 388
+L K KLE + KD+++ E K+ ATE +V L ++ ++E + K
Sbjct: 936 NAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKL 995
Query: 389 SEERSG---TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDA 559
S+E+ T QQ L + Q D+ N +L + E+++D L L++ + L D
Sbjct: 996 SKEKKALQETHQQTLDDLQAEEDKVN----ILTKAKTKLEQQVDDLEGSLEQEKKLRMDL 1051
Query: 560 DGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXEL 676
+ ++ L ++ E+ + D K+ E E+
Sbjct: 1052 ERAKRKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEI 1090
Score = 43.6 bits (98), Expect = 7e-04
Identities = 43/180 (23%), Positives = 87/180 (48%)
Frame = +2
Query: 83 TMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 262
T+ + K+ +A++ +D E + K+ ++V +L+ L Q E+ L +
Sbjct: 991 TIAKLSKEKKALQETHQQTLDDLQAEEDKVNILTKAKTKLEQQVDDLEGSLEQ-EKKLRM 1049
Query: 263 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 442
+ LE+A + LE K A E+ + N K QQ++E LEK E K +E +Q+
Sbjct: 1050 D---LERAKRKLEGDLK--LAQESTMDMENDK-QQLDEKLEKKEFEISNLISK-IEDEQA 1102
Query: 443 ADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 622
+ L+ + ++ + R+++L +++ R A+ + ++SR+L + + LE A
Sbjct: 1103 VEIQ------LQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLSRELEEISERLEEA 1156
Score = 42.7 bits (96), Expect = 0.001
Identities = 47/208 (22%), Positives = 98/208 (47%), Gaps = 22/208 (10%)
Frame = +2
Query: 161 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 340
+Q+ D + + +++ EL+K QVE++ + LE+A LE +E ++ + E+
Sbjct: 1509 QQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLEL 1568
Query: 341 ----AALNRKVQQIEED---LEKSEERSGTAQQKLLEAQ-QSADENNRMCKVLENRAQQD 496
+ ++RK+ + +E+ L+++ R Q L+A+ +S ++ R+ K +E +
Sbjct: 1569 NQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEM 1628
Query: 497 EERM--------DQLTNQ------LKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRV 634
E ++ + L N LKE +L +DA +++ +LA VE + + +
Sbjct: 1629 EIQLNHANRLAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEI 1688
Query: 635 KSGDAKISXLEXELKVVGNSLKSLEVSE 718
+ A + E K+ L L+ SE
Sbjct: 1689 EELWATLEQTERSRKIAEQEL--LDASE 1714
Score = 41.1 bits (92), Expect = 0.004
Identities = 29/134 (21%), Positives = 63/134 (47%), Gaps = 7/134 (5%)
Frame = +2
Query: 326 TEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEER 505
TE E+A + + Q+ +++L KSE + ++K++ + ++ + + EER
Sbjct: 848 TEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAEER 907
Query: 506 MDQLTN-------QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXL 664
+QL ++KE AE+ + + E++ K +EDE + + + ++ +
Sbjct: 908 CEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKV 967
Query: 665 EXELKVVGNSLKSL 706
E E N +K+L
Sbjct: 968 EKEKHATENKVKNL 981
Score = 37.5 bits (83), Expect = 0.049
Identities = 37/188 (19%), Positives = 81/188 (43%), Gaps = 5/188 (2%)
Frame = +2
Query: 161 EQQARDANLRAEKVNEEVRELQKKL-AQVEEDLILNKNKLEQANKDLEEKEKQLTATEAE 337
E+Q D + E+++E + E AQVE LNK + + K + E+ EA
Sbjct: 1136 EKQRSDLSRELEEISERLEEAGGATSAQVE----LNKKREAEFQKLRRDLEEATLQHEAM 1191
Query: 338 VAALNRK----VQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEER 505
VAAL +K + ++ E ++ + +++ E + D+ + + + E+
Sbjct: 1192 VAALRKKHADSMAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKM 1251
Query: 506 MDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVV 685
L +Q+ E + E+ ++++ + A ++ E ++ DA +S L +
Sbjct: 1252 CRSLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQAS 1311
Query: 686 GNSLKSLE 709
++ L+
Sbjct: 1312 TQQIEELK 1319
Score = 35.9 bits (79), Expect = 0.15
Identities = 43/210 (20%), Positives = 89/210 (42%), Gaps = 10/210 (4%)
Frame = +2
Query: 110 QAMKLEKDNAMDKADTCEQQA--RDANLRAEKVNEEVRELQKKLAQVEEDL---ILNKN- 271
Q +LEK + + CE QA +A E ++ +Q +L QV+ ++ I K+
Sbjct: 1525 QIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDE 1584
Query: 272 KLEQANKDLEEKEKQLTAT-EAEVAALN---RKVQQIEEDLEKSEERSGTAQQKLLEAQQ 439
+++Q ++ + + +T +AE+ + N R +++E DL + E + A + E+ +
Sbjct: 1585 EIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLAAESLR 1644
Query: 440 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 619
+ + K + + L QL A + +E+ L E ++
Sbjct: 1645 NYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWATLEQTERSRKI 1704
Query: 620 AEDRVKSGDAKISXLEXELKVVGNSLKSLE 709
AE + ++ L + + N+ K LE
Sbjct: 1705 AEQELLDASERVQLLHTQNTSLINTKKKLE 1734
Score = 35.9 bits (79), Expect = 0.15
Identities = 36/175 (20%), Positives = 82/175 (46%), Gaps = 15/175 (8%)
Frame = +2
Query: 161 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLE---QANKDLEEKEKQLTATE 331
EQ+ DA+ R + ++ + L ++E D+ ++++E Q +++ EEK K+
Sbjct: 1706 EQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEEKAKKAITDA 1765
Query: 332 AEVAALNRKVQQIEEDLEKS----EERSGTAQQKLLEAQQSADENNR--------MCKVL 475
A +A +K Q LE+ E+ Q +L EA+Q A + + + L
Sbjct: 1766 AMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVREL 1825
Query: 476 ENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKS 640
E + +++R + L++ ++ +++E + + ++D ++ + +VKS
Sbjct: 1826 EGEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQAKVKS 1880
>X51592-1|CAA35941.1| 1437|Homo sapiens fetal-myosin heavy chain (1437
AA) protein.
Length = 1437
Score = 61.3 bits (142), Expect = 3e-09
Identities = 45/212 (21%), Positives = 106/212 (50%), Gaps = 5/212 (2%)
Frame = +2
Query: 83 TMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 262
T ++ + ++ E + + ++ E++A+ A A + EE+++ Q A +E +
Sbjct: 1229 TKKKLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLER---M 1285
Query: 263 NKNKLEQANKDL-----EEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 427
KN LEQ KDL E ++ L + ++ L +V+++E ++E ++R+ A + L
Sbjct: 1286 KKN-LEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLR 1344
Query: 428 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 607
+ ++ E + + ++ +D+L ++K + AE+A+ +S+ K ++
Sbjct: 1345 KHERRVKELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLSKFRKLQH 1404
Query: 608 ELEVAEDRVKSGDAKISXLEXELKVVGNSLKS 703
ELE AE+R +++++ L + + V + +
Sbjct: 1405 ELEEAEERADIAESQVNKLRVKSREVHTKISA 1436
Score = 52.0 bits (119), Expect = 2e-06
Identities = 52/219 (23%), Positives = 102/219 (46%), Gaps = 16/219 (7%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQA-MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQV 244
++K T+ K +Q ++ E D+ D + CEQ ++ ++ E +EV E ++ ++
Sbjct: 376 EEKMVTLLKEKNDLQLQVQSEADSLADAEERCEQLIKN-KIQLEAKIKEVTERAEEEEEI 434
Query: 245 EEDLILNKNKLE----QANKDLEEKE-------KQLTATEAEVAALNRKVQQIEEDLEK- 388
+L K KLE + KD+++ E K+ ATE +V L ++ ++E + K
Sbjct: 435 NAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKL 494
Query: 389 SEERSG---TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDA 559
S+E+ T QQ L + Q D+ N +L + E+++D L L++ + L D
Sbjct: 495 SKEKKALQETHQQTLDDLQAEEDKVN----ILTKAKTKLEQQVDDLEGSLEQEKKLRMDL 550
Query: 560 DGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXEL 676
+ ++ L ++ E+ + D K+ E E+
Sbjct: 551 ERAKRKLEGDLKLAQESTMDNENDKQQLDEKLEKKEFEI 589
Score = 51.6 bits (118), Expect = 3e-06
Identities = 54/221 (24%), Positives = 97/221 (43%), Gaps = 7/221 (3%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
+++ +A+ +Q+ + + D ++ + ++ + K N EV + + E
Sbjct: 823 EEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWR---TNTE 879
Query: 248 EDLILNKNKLEQANKDL----EEKEKQLTATEAEVAALNRKVQQIE---EDLEKSEERSG 406
D I +LE+A K L +E E+ + A A+ A+L + Q+++ EDL ERS
Sbjct: 880 TDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSN 939
Query: 407 TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSR 586
A L + Q++ D KVL Q+ EE +L KE+R L+ + +
Sbjct: 940 AACAALDKKQRNFD------KVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEE 993
Query: 587 KLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLE 709
L D+LE K+ +IS L ++ G + LE
Sbjct: 994 SL----DQLETLRRENKNLQQEISDLTEQIAEGGKQIHELE 1030
Score = 43.2 bits (97), Expect = 0.001
Identities = 43/180 (23%), Positives = 87/180 (48%)
Frame = +2
Query: 83 TMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 262
T+ + K+ +A++ +D E + K+ ++V +L+ L Q E+ L +
Sbjct: 490 TIAKLSKEKKALQETHQQTLDDLQAEEDKVNILTKAKTKLEQQVDDLEGSLEQ-EKKLRM 548
Query: 263 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 442
+ LE+A + LE K A E+ + N K QQ++E LEK E K +E +Q+
Sbjct: 549 D---LERAKRKLEGDLK--LAQESTMDNENDK-QQLDEKLEKKEFEISNLISK-IEDEQA 601
Query: 443 ADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 622
+ L+ + ++ + R+++L +++ R A+ + ++SR+L + + LE A
Sbjct: 602 VEIQ------LQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLSRELEEISERLEEA 655
Score = 42.7 bits (96), Expect = 0.001
Identities = 47/208 (22%), Positives = 98/208 (47%), Gaps = 22/208 (10%)
Frame = +2
Query: 161 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 340
+Q+ D + + +++ EL+K QVE++ + LE+A LE +E ++ + E+
Sbjct: 1009 QQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLEL 1068
Query: 341 ----AALNRKVQQIEED---LEKSEERSGTAQQKLLEAQ-QSADENNRMCKVLENRAQQD 496
+ ++RK+ + +E+ L+++ R Q L+A+ +S ++ R+ K +E +
Sbjct: 1069 NQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEM 1128
Query: 497 EERM--------DQLTNQ------LKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRV 634
E ++ + L N LKE +L +DA +++ +LA VE + + +
Sbjct: 1129 EIQLNHANRLAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEI 1188
Query: 635 KSGDAKISXLEXELKVVGNSLKSLEVSE 718
+ A + E K+ L L+ SE
Sbjct: 1189 EELWATLEQTERSRKIAEQEL--LDASE 1214
Score = 41.1 bits (92), Expect = 0.004
Identities = 29/134 (21%), Positives = 63/134 (47%), Gaps = 7/134 (5%)
Frame = +2
Query: 326 TEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEER 505
TE E+A + + Q+ +++L KSE + ++K++ + ++ + + EER
Sbjct: 347 TEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAEER 406
Query: 506 MDQLTN-------QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXL 664
+QL ++KE AE+ + + E++ K +EDE + + + ++ +
Sbjct: 407 CEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKV 466
Query: 665 EXELKVVGNSLKSL 706
E E N +K+L
Sbjct: 467 EKEKHATENKVKNL 480
Score = 35.9 bits (79), Expect = 0.15
Identities = 43/210 (20%), Positives = 89/210 (42%), Gaps = 10/210 (4%)
Frame = +2
Query: 110 QAMKLEKDNAMDKADTCEQQA--RDANLRAEKVNEEVRELQKKLAQVEEDL---ILNKN- 271
Q +LEK + + CE QA +A E ++ +Q +L QV+ ++ I K+
Sbjct: 1025 QIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDE 1084
Query: 272 KLEQANKDLEEKEKQLTAT-EAEVAALN---RKVQQIEEDLEKSEERSGTAQQKLLEAQQ 439
+++Q ++ + + +T +AE+ + N R +++E DL + E + A + E+ +
Sbjct: 1085 EIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLAAESLR 1144
Query: 440 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 619
+ + K + + L QL A + +E+ L E ++
Sbjct: 1145 NYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWATLEQTERSRKI 1204
Query: 620 AEDRVKSGDAKISXLEXELKVVGNSLKSLE 709
AE + ++ L + + N+ K LE
Sbjct: 1205 AEQELLDASERVQLLHTQNTSLINTKKKLE 1234
Score = 35.9 bits (79), Expect = 0.15
Identities = 36/175 (20%), Positives = 82/175 (46%), Gaps = 15/175 (8%)
Frame = +2
Query: 161 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLE---QANKDLEEKEKQLTATE 331
EQ+ DA+ R + ++ + L ++E D+ ++++E Q +++ EEK K+
Sbjct: 1206 EQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEEKAKKAITDA 1265
Query: 332 AEVAALNRKVQQIEEDLEKS----EERSGTAQQKLLEAQQSADENNR--------MCKVL 475
A +A +K Q LE+ E+ Q +L EA+Q A + + + L
Sbjct: 1266 AMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVREL 1325
Query: 476 ENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKS 640
E + +++R + L++ ++ +++E + + ++D ++ + +VKS
Sbjct: 1326 EGEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQAKVKS 1380
Score = 34.7 bits (76), Expect = 0.35
Identities = 36/189 (19%), Positives = 83/189 (43%), Gaps = 6/189 (3%)
Frame = +2
Query: 161 EQQARDANLRAEKVNEEVRELQKKL-AQVEEDLILNKNKLEQANKDLEEKEKQLTATEAE 337
E+Q D + E+++E + E AQVE LNK + + K + E+ EA
Sbjct: 635 EKQRSDLSRELEEISERLEEAGGATSAQVE----LNKKREAEFQKLRRDLEEATLQHEAM 690
Query: 338 VAALNRK----VQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLEN-RAQQDEE 502
VAAL +K + ++ E ++ + +++ E + D+ + + + + +++
Sbjct: 691 VAALRKKHADSMAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKD 750
Query: 503 RMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKV 682
L +Q+ E + E+ ++++ + A ++ E ++ DA +S L +
Sbjct: 751 GGRSLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQA 810
Query: 683 VGNSLKSLE 709
++ L+
Sbjct: 811 STQQIEELK 819
>M12127-1|AAA36774.1| 131|Homo sapiens protein ( Human cytoskeletal
tropomyosin isoform (3.0 kb) mRNA, 3' end. ).
Length = 131
Score = 61.3 bits (142), Expect = 3e-09
Identities = 30/60 (50%), Positives = 42/60 (70%)
Frame = +2
Query: 545 LAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXK 724
+AE+AD K +EV+RKL +E ELE AE+R + ++K LE EL+ V N+LKSLE + K
Sbjct: 1 IAEEADRKYEEVARKLVILEGELERAEERAEVSESKCGDLEEELRTVTNNLKSLEAASEK 60
>BC114545-1|AAI14546.1| 1939|Homo sapiens myosin, heavy chain 1,
skeletal muscle, adult protein.
Length = 1939
Score = 61.3 bits (142), Expect = 3e-09
Identities = 49/216 (22%), Positives = 111/216 (51%), Gaps = 7/216 (3%)
Frame = +2
Query: 83 TMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 262
T ++ + ++ E ++ + +A E++A+ A A + EE+++ Q A +E +
Sbjct: 1730 TKKKLETDISQIQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLER---M 1786
Query: 263 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 442
KN LEQ KDL+ + + A + + +++Q++E + + E + Q++ +EA +
Sbjct: 1787 KKN-LEQTVKDLQHRLDE--AEQLALKGGKKQIQKLEARVRELEGEVESEQKRNVEAVKG 1843
Query: 443 ADENNRMCKVLENRAQQD-------EERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFV 601
++ R K L + ++D ++ +D+L ++K + AE+A+ +S+ K +
Sbjct: 1844 LRKHERKVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNVNLSKFRRI 1903
Query: 602 EDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLE 709
+ ELE AE+R +++++ L + + V + S E
Sbjct: 1904 QHELEEAEERADIAESQVNKLRVKSREVHTKIISEE 1939
Score = 55.2 bits (127), Expect = 2e-07
Identities = 47/212 (22%), Positives = 100/212 (47%), Gaps = 7/212 (3%)
Frame = +2
Query: 95 IKKKMQA---MKLEKDNAMDKAD-TCEQQARDANLRAE--KVNEEVRELQKKLAQVEEDL 256
IK K+Q +K + A D+ + E A+ L E ++ +++ +L+ LA+VE++
Sbjct: 913 IKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEK 972
Query: 257 ILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQ 436
+NK++ +++ ++ + E AL QQ +DL+ E++ T + ++ +
Sbjct: 973 HATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLE 1032
Query: 437 QSADENNRMCKVLENRAQQDEERMD-QLTNQLKEARLLAEDADGKSDEVSRKLAFVEDEL 613
Q D+ + E + + D ER +L LK A+ D + ++ KL E E+
Sbjct: 1033 QQVDDLEGSLE-QEKKIRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEM 1091
Query: 614 EVAEDRVKSGDAKISXLEXELKVVGNSLKSLE 709
+ +++ A L+ ++K + ++ LE
Sbjct: 1092 SGLQSKIEDEQALGMQLQKKIKELQARIEELE 1123
Score = 45.6 bits (103), Expect = 2e-04
Identities = 31/134 (23%), Positives = 63/134 (47%), Gaps = 7/134 (5%)
Frame = +2
Query: 326 TEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEER 505
TE E+A + + ++ +E+L K+E + ++K++ Q ++ + + EER
Sbjct: 849 TEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLADAEER 908
Query: 506 MDQLTN-------QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXL 664
DQL ++KE AED + + E++ K +EDE + + + ++ +
Sbjct: 909 CDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKV 968
Query: 665 EXELKVVGNSLKSL 706
E E N +K+L
Sbjct: 969 EKEKHATENKVKNL 982
Score = 37.5 bits (83), Expect = 0.049
Identities = 48/216 (22%), Positives = 101/216 (46%), Gaps = 1/216 (0%)
Frame = +2
Query: 80 ATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLI 259
+TMD K Q + K + + + + D ++ ++++ELQ ++ ++EE++
Sbjct: 1069 STMDIENDKQQLDEKLKKKEFEMSGL-QSKIEDEQALGMQLQKKIKELQARIEELEEEI- 1126
Query: 260 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 439
+ E+A++ EK++ + L+R++++I E LE E T+ Q + ++
Sbjct: 1127 ----EAERASRAKAEKQR---------SDLSRELEEISERLE--EAGGATSAQIEMNKKR 1171
Query: 440 SADENNRMCKVLENRAQQDEERMDQLTNQLKEA-RLLAEDADGKSDEVSRKLAFVEDELE 616
A E +M + LE Q E L + ++ L E D V +KL + E++
Sbjct: 1172 EA-EFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQID-NLQRVKQKLEKEKSEMK 1229
Query: 617 VAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXK 724
+ D + S +S + L+ + +L+ ++SE K
Sbjct: 1230 MEIDDLASNMETVSKAKGNLEKMCRALED-QLSEIK 1264
>AK097432-1|BAC05050.1| 466|Homo sapiens protein ( Homo sapiens
cDNA FLJ40113 fis, clone TESTI2008621. ).
Length = 466
Score = 61.3 bits (142), Expect = 3e-09
Identities = 42/185 (22%), Positives = 96/185 (51%), Gaps = 2/185 (1%)
Frame = +2
Query: 86 MDAIKKKMQAMKLEKDNAMDKADTC-EQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 262
++++ +++QA ++E + + + E++ R+ R + E +RE +++L + EE L
Sbjct: 173 LESVGRQLQA-EVENNQMLSLLNRRQEERLREQEERLREQEERLREQEERLHEQEERLCE 231
Query: 263 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 442
+ +L + + L E E++L E + ++ + EE L + EER +++L E ++
Sbjct: 232 QEERLCEQEERLREHEERLCEQEERLREHEERLCEQEERLCEQEERLREQEERLCEQEER 291
Query: 443 -ADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 619
++ R+C+ E R ++ EER+ + +L+E + + + E +L E+ L
Sbjct: 292 LCEQEERLCEQ-EERLREQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEERLRE 350
Query: 620 AEDRV 634
E+R+
Sbjct: 351 QEERL 355
Score = 56.8 bits (131), Expect = 7e-08
Identities = 39/166 (23%), Positives = 82/166 (49%), Gaps = 1/166 (0%)
Frame = +2
Query: 182 NLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKV 361
+L + E +RE +++L + EE L + +L + + L E+E++L E + ++
Sbjct: 191 SLLNRRQEERLREQEERLREQEERLREQEERLHEQEERLCEQEERLCEQEERLREHEERL 250
Query: 362 QQIEEDLEKSEERSGTAQQKLLEAQQS-ADENNRMCKVLENRAQQDEERMDQLTNQLKEA 538
+ EE L + EER +++L E ++ ++ R+C+ E R + EER+ + +L+E
Sbjct: 251 CEQEERLREHEERLCEQEERLCEQEERLREQEERLCE-QEERLCEQEERLCEQEERLREQ 309
Query: 539 RLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXEL 676
+ + + E +L E+ L E+R+ + ++ E L
Sbjct: 310 EERLCEQEERLREQEERLCEQEERLREQEERLCEQEERLREQEERL 355
Score = 56.4 bits (130), Expect = 1e-07
Identities = 35/132 (26%), Positives = 71/132 (53%), Gaps = 1/132 (0%)
Frame = +2
Query: 161 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 340
E++ R+ R + E +RE +++L + EE L + +L + + L E+E++L E +
Sbjct: 240 EERLREHEERLCEQEERLREHEERLCEQEERLCEQEERLREQEERLCEQEERLCEQEERL 299
Query: 341 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA-DENNRMCKVLENRAQQDEERMDQL 517
++++ EE L + EER +++L E ++ ++ R+C+ E R ++ EER+ +
Sbjct: 300 CEQEERLREQEERLCEQEERLREQEERLCEQEERLREQEERLCEQ-EERLREQEERLCEQ 358
Query: 518 TNQLKEARLLAE 553
+ RLL E
Sbjct: 359 EKLPGQERLLEE 370
Score = 55.6 bits (128), Expect = 2e-07
Identities = 40/192 (20%), Positives = 93/192 (48%), Gaps = 1/192 (0%)
Frame = +2
Query: 95 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 274
++K+++++ + ++ R R + E +RE +++L + EE L + +
Sbjct: 169 LRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLREQEERLHEQEER 228
Query: 275 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS-ADE 451
L + + L E+E++L E + ++++ EE L + EER +++L E ++ ++
Sbjct: 229 LCEQEERLCEQEERLREHEERLCEQEERLREHEERLCEQEERLCEQEERLREQEERLCEQ 288
Query: 452 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDR 631
R+C+ E R + EER+ + +L E + + + E +L E+ L E+R
Sbjct: 289 EERLCEQ-EERLCEQEERLREQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEER 347
Query: 632 VKSGDAKISXLE 667
++ + ++ E
Sbjct: 348 LREQEERLCEQE 359
Score = 55.6 bits (128), Expect = 2e-07
Identities = 40/178 (22%), Positives = 84/178 (47%), Gaps = 5/178 (2%)
Frame = +2
Query: 161 EQQARDANLRAEKVNEEV-----RELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTA 325
E ++ L+AE N ++ R +++L + EE L + +L + + L E+E++L
Sbjct: 172 ELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLREQEERLHEQEERLCE 231
Query: 326 TEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEER 505
E + ++++ EE L + EER +++L E ++ E + E R + EER
Sbjct: 232 QEERLCEQEERLREHEERLCEQEERLREHEERLCEQEERLCEQEERLREQEERLCEQEER 291
Query: 506 MDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELK 679
+ + +L E + + + E +L E+ L E+R++ + ++ E L+
Sbjct: 292 LCEQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEERLR 349
Score = 52.0 bits (119), Expect = 2e-06
Identities = 34/156 (21%), Positives = 78/156 (50%), Gaps = 3/156 (1%)
Frame = +2
Query: 89 DAIKKKMQAMKLEKDNAMDKADT-CEQQAR--DANLRAEKVNEEVRELQKKLAQVEEDLI 259
+ ++++ + ++ +++ ++ + CEQ+ R + R + E + E +++L + EE L
Sbjct: 206 ERLREQEERLREQEERLHEQEERLCEQEERLCEQEERLREHEERLCEQEERLREHEERLC 265
Query: 260 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 439
+ +L + + L E+E++L E + ++ + EE L + EER +++L E ++
Sbjct: 266 EQEERLCEQEERLREQEERLCEQEERLCEQEERLCEQEERLREQEERLCEQEERLREQEE 325
Query: 440 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLL 547
E + E R + EER+ + +L E L
Sbjct: 326 RLCEQEERLREQEERLCEQEERLREQEERLCEQEKL 361
Score = 46.4 bits (105), Expect = 1e-04
Identities = 34/135 (25%), Positives = 69/135 (51%), Gaps = 2/135 (1%)
Frame = +2
Query: 158 CEQQAR--DANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATE 331
CEQ+ R + R + E +RE +++L + EE L + +L + + L E+E++L E
Sbjct: 286 CEQEERLCEQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEERLREQEERLCEQE 345
Query: 332 AEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMD 511
+ ++ E++ +ER +KLLE ++ +E R+ + E ++ E+ ++
Sbjct: 346 ERLREQEERL--CEQEKLPGQERLLEEVEKLLEQERRQEEQERLLE-RERLLEEVEKLLE 402
Query: 512 QLTNQLKEARLLAED 556
Q Q ++ RLL +
Sbjct: 403 QERRQEEQERLLERE 417
Score = 42.7 bits (96), Expect = 0.001
Identities = 32/118 (27%), Positives = 62/118 (52%), Gaps = 2/118 (1%)
Frame = +2
Query: 158 CEQQARDANLRAEKVNEEVREL--QKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATE 331
CEQ+ E++ EEV +L Q++ + +E L+ + LE+ K LE++ +Q +
Sbjct: 356 CEQEKLPGQ---ERLLEEVEKLLEQERRQEEQERLLERERLLEEVEKLLEQERRQ--EEQ 410
Query: 332 AEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEER 505
+ R ++++E+ LE +ER Q++LLE ++ DE + +E +Q+ R
Sbjct: 411 ERLLERERLLEEVEKLLE--QERRQEEQERLLERERLLDEVEELLDEVEELLEQERLR 466
Score = 42.3 bits (95), Expect = 0.002
Identities = 32/138 (23%), Positives = 64/138 (46%), Gaps = 1/138 (0%)
Frame = +2
Query: 266 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 445
+++ K+LE +QL A L+ ++ EE L + EER +++L E ++
Sbjct: 163 QDETNHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLREQEERL 222
Query: 446 -DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 622
++ R+C+ E R + EER+ + +L E + + + E +L E+ L
Sbjct: 223 HEQEERLCE-QEERLCEQEERLREHEERLCEQEERLREHEERLCEQEERLCEQEERLREQ 281
Query: 623 EDRVKSGDAKISXLEXEL 676
E+R+ + ++ E L
Sbjct: 282 EERLCEQEERLCEQEERL 299
Score = 39.5 bits (88), Expect = 0.012
Identities = 33/173 (19%), Positives = 76/173 (43%), Gaps = 1/173 (0%)
Frame = +2
Query: 161 EQQARDANLRAEKVNEEVRELQKKLAQ-VEEDLILNKNKLEQANKDLEEKEKQLTATEAE 337
E++ + +L +K+ + +L+ + A+ + + +K+EQ + K+L + +
Sbjct: 121 EEKKHEIHL-VQKLGRSLFKLKNQTAEPLAPEPPAGPSKVEQLQDETNHLRKELESVGRQ 179
Query: 338 VAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQL 517
+ A Q + + EER +++L E ++ E E R + EER+ +
Sbjct: 180 LQAEVENNQMLSLLNRRQEERLREQEERLREQEERLREQEERLHEQEERLCEQEERLCEQ 239
Query: 518 TNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXEL 676
+L+E + + + E +L E+ L E+R++ + ++ E L
Sbjct: 240 EERLREHEERLCEQEERLREHEERLCEQEERLCEQEERLREQEERLCEQEERL 292
>AF111785-1|AAD29951.1| 1939|Homo sapiens myosin heavy chain IIx/d
protein.
Length = 1939
Score = 61.3 bits (142), Expect = 3e-09
Identities = 49/216 (22%), Positives = 111/216 (51%), Gaps = 7/216 (3%)
Frame = +2
Query: 83 TMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 262
T ++ + ++ E ++ + +A E++A+ A A + EE+++ Q A +E +
Sbjct: 1730 TKKKLETDISQIQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLER---M 1786
Query: 263 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 442
KN LEQ KDL+ + + A + + +++Q++E + + E + Q++ +EA +
Sbjct: 1787 KKN-LEQTVKDLQHRLDE--AEQLALKGGKKQIQKLEARVRELEGEVESEQKRNVEAVKG 1843
Query: 443 ADENNRMCKVLENRAQQD-------EERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFV 601
++ R K L + ++D ++ +D+L ++K + AE+A+ +S+ K +
Sbjct: 1844 LRKHERKVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNVNLSKFRRI 1903
Query: 602 EDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLE 709
+ ELE AE+R +++++ L + + V + S E
Sbjct: 1904 QHELEEAEERADIAESQVNKLRVKSREVHTKIISEE 1939
Score = 56.8 bits (131), Expect = 7e-08
Identities = 48/212 (22%), Positives = 101/212 (47%), Gaps = 7/212 (3%)
Frame = +2
Query: 95 IKKKMQA---MKLEKDNAMDKAD-TCEQQARDANLRAE--KVNEEVRELQKKLAQVEEDL 256
IK K+Q +K + A D+ + E A+ L E ++ +++ +L+ LA+VE++
Sbjct: 913 IKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEK 972
Query: 257 ILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQ 436
+NK++ +++ ++ + E AL QQ +DL+ E++ T + ++ +
Sbjct: 973 HATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLE 1032
Query: 437 QSADENNRMCKVLENRAQQDEERMD-QLTNQLKEARLLAEDADGKSDEVSRKLAFVEDEL 613
Q D+ + E + + D ER +L LK A+ A D + ++ KL E E+
Sbjct: 1033 QQVDDLEGSLE-QEKKIRMDLERAKRKLEGDLKLAQESAMDIENDKQQLDEKLKKKEFEM 1091
Query: 614 EVAEDRVKSGDAKISXLEXELKVVGNSLKSLE 709
+ +++ A L+ ++K + ++ LE
Sbjct: 1092 SGLQSKIEDEQALGMQLQKKIKELQARIEELE 1123
Score = 45.6 bits (103), Expect = 2e-04
Identities = 31/134 (23%), Positives = 63/134 (47%), Gaps = 7/134 (5%)
Frame = +2
Query: 326 TEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEER 505
TE E+A + + ++ +E+L K+E + ++K++ Q ++ + + EER
Sbjct: 849 TEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLADAEER 908
Query: 506 MDQLTN-------QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXL 664
DQL ++KE AED + + E++ K +EDE + + + ++ +
Sbjct: 909 CDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKV 968
Query: 665 EXELKVVGNSLKSL 706
E E N +K+L
Sbjct: 969 EKEKHATENKVKNL 982
Score = 35.5 bits (78), Expect = 0.20
Identities = 47/216 (21%), Positives = 100/216 (46%), Gaps = 1/216 (0%)
Frame = +2
Query: 80 ATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLI 259
+ MD K Q + K + + + + D ++ ++++ELQ ++ ++EE++
Sbjct: 1069 SAMDIENDKQQLDEKLKKKEFEMSGL-QSKIEDEQALGMQLQKKIKELQARIEELEEEI- 1126
Query: 260 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 439
+ E+A++ EK++ + L+R++++I E LE E T+ Q + ++
Sbjct: 1127 ----EAERASRAKAEKQR---------SDLSRELEEISERLE--EAGGATSAQIEMNKKR 1171
Query: 440 SADENNRMCKVLENRAQQDEERMDQLTNQLKEA-RLLAEDADGKSDEVSRKLAFVEDELE 616
A E +M + LE Q E L + ++ L E D V +KL + E++
Sbjct: 1172 EA-EFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQID-NLQRVKQKLEKEKSEMK 1229
Query: 617 VAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXK 724
+ D + S +S + L+ + +L+ ++SE K
Sbjct: 1230 MEIDDLASNMETVSKAKGNLEKMCRALED-QLSEIK 1264
>X13939-1|CAA32122.1| 328|Homo sapiens laminin B2 protein.
Length = 328
Score = 60.5 bits (140), Expect = 6e-09
Identities = 46/172 (26%), Positives = 76/172 (44%), Gaps = 6/172 (3%)
Frame = +2
Query: 182 NLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKV 361
N + NE+ RE Q+ L D KNK +A + +K T+T+AE +V
Sbjct: 114 NQTITEANEKTREAQQALGSAAADATEAKNKAHEAERIASAVQKNATSTKAEAERTFAEV 173
Query: 362 QQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEAR 541
++ ++ ++ A+++L Q AD++ M + AQ+ E + N +
Sbjct: 174 TDLDNEVNNMLKQLQEAEKELKRKQDDADQDMMMAGMASQAAQEAEINARKAKNSVTSLL 233
Query: 542 LLAED---ADGKSDEVS-RKLAFVEDELEVAEDRVKSG--DAKISXLEXELK 679
+ D G+ D V KL +E L A+D +K D K+S LE E K
Sbjct: 234 SIINDLLEQLGQLDTVDLNKLNEIEGTLNKAKDEMKVSDLDRKVSDLENEAK 285
Score = 48.4 bits (110), Expect = 3e-05
Identities = 51/219 (23%), Positives = 89/219 (40%), Gaps = 7/219 (3%)
Frame = +2
Query: 71 QKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEE 250
QK + +++ M+ +LE N ++K T +Q A RA+ E KK
Sbjct: 21 QKLKDYEDLREDMRGKELEVKNLLEKGKTEQQTADQLLARADAAKALAEEAAKK----GR 76
Query: 251 DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLE 430
D + N + KD + + T AE A RK+ I + + ++ E++ AQQ L
Sbjct: 77 DTLQEANDILNNLKDFDRRVND-NKTAAEEAL--RKIPAINQTITEANEKTREAQQALGS 133
Query: 431 AQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDE 610
A A E E A ++ + + D D + + + ++L E E
Sbjct: 134 AAADATEAKNKAHEAERIASAVQKNATSTKAEAERTFAEVTDLDNEVNNMLKQLQEAEKE 193
Query: 611 L-----EVAEDRVKSGDAKISXLEXEL--KVVGNSLKSL 706
L + +D + +G A + E E+ + NS+ SL
Sbjct: 194 LKRKQDDADQDMMMAGMASQAAQEAEINARKAKNSVTSL 232
>M55210-1|AAA59492.1| 1609|Homo sapiens laminin B2 chain protein.
Length = 1609
Score = 60.5 bits (140), Expect = 6e-09
Identities = 46/172 (26%), Positives = 76/172 (44%), Gaps = 6/172 (3%)
Frame = +2
Query: 182 NLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKV 361
N + NE+ RE Q+ L D KNK +A + +K T+T+AE +V
Sbjct: 1395 NQTITEANEKTREAQQALGSAAADATEAKNKAHEAERIASAVQKNATSTKAEAERTFAEV 1454
Query: 362 QQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEAR 541
++ ++ ++ A+++L Q AD++ M + AQ+ E + N +
Sbjct: 1455 TDLDNEVNNMLKQLQEAEKELKRKQDDADQDMMMAGMASQAAQEAEINARKAKNSVTSLL 1514
Query: 542 LLAED---ADGKSDEVS-RKLAFVEDELEVAEDRVKSG--DAKISXLEXELK 679
+ D G+ D V KL +E L A+D +K D K+S LE E K
Sbjct: 1515 SIINDLLEQLGQLDTVDLNKLNEIEGTLNKAKDEMKVSDLDRKVSDLENEAK 1566
Score = 48.4 bits (110), Expect = 3e-05
Identities = 51/219 (23%), Positives = 89/219 (40%), Gaps = 7/219 (3%)
Frame = +2
Query: 71 QKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEE 250
QK + +++ M+ +LE N ++K T +Q A RA+ E KK
Sbjct: 1302 QKLKDYEDLREDMRGKELEVKNLLEKGKTEQQTADQLLARADAAKALAEEAAKK----GR 1357
Query: 251 DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLE 430
D + N + KD + + T AE A RK+ I + + ++ E++ AQQ L
Sbjct: 1358 DTLQEANDILNNLKDFDRRVND-NKTAAEEAL--RKIPAINQTITEANEKTREAQQALGS 1414
Query: 431 AQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDE 610
A A E E A ++ + + D D + + + ++L E E
Sbjct: 1415 AAADATEAKNKAHEAERIASAVQKNATSTKAEAERTFAEVTDLDNEVNNMLKQLQEAEKE 1474
Query: 611 L-----EVAEDRVKSGDAKISXLEXEL--KVVGNSLKSL 706
L + +D + +G A + E E+ + NS+ SL
Sbjct: 1475 LKRKQDDADQDMMMAGMASQAAQEAEINARKAKNSVTSL 1513
Score = 37.5 bits (83), Expect = 0.049
Identities = 29/141 (20%), Positives = 57/141 (40%), Gaps = 2/141 (1%)
Frame = +2
Query: 143 DKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLT 322
D+ E++ D A+ V + + L +L +V L ++L+ +EE
Sbjct: 1073 DRLKEAEREVMDLLREAQDVKDVDQNLMDRLQRVNNTLSSQISRLQNIRNTIEETGNLAE 1132
Query: 323 ATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENR--AQQD 496
A V R ++ +LEK+ + A + + + + D NN E R A++
Sbjct: 1133 QARAHVENTERLIEIASRELEKA--KVAAANVSVTQPESTGDPNNMTLLAEEARKLAERH 1190
Query: 497 EERMDQLTNQLKEARLLAEDA 559
++ D + K A + +A
Sbjct: 1191 KQEADDIVRVAKTANDTSTEA 1211
Score = 34.3 bits (75), Expect = 0.46
Identities = 48/224 (21%), Positives = 100/224 (44%), Gaps = 18/224 (8%)
Frame = +2
Query: 83 TMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 262
T A + +++ + E + + +A + ++ R ++VN + +L + +
Sbjct: 1067 TDQAFEDRLKEAEREVMDLLREAQDVKDVDQNLMDRLQRVNNTLSSQISRLQNIRNTIEE 1126
Query: 263 NKNKLEQANKDLEEKEK--QLTATE---AEVAALNRKVQQIEEDLEKSE-ERSGTAQQKL 424
N EQA +E E+ ++ + E A+VAA N V Q E + + +KL
Sbjct: 1127 TGNLAEQARAHVENTERLIEIASRELEKAKVAAANVSVTQPESTGDPNNMTLLAEEARKL 1186
Query: 425 LEA-QQSADENNRMCKVLENRAQQDEERM-------DQLTNQLKEARLLAEDADGKSDEV 580
E +Q AD+ R+ K + + + + +Q +++E E A S ++
Sbjct: 1187 AERHKQEADDIVRVAKTANDTSTEAYNLLLRTLAGENQTAFEIEELNRKYEQAKNISQDL 1246
Query: 581 SRKLAFVEDELEVAEDR---VKSGDAKISXLEXE-LKVVGNSLK 700
++ A V +E + A D+ + + A++S L+ E L+ N++K
Sbjct: 1247 EKQAARVHEEAKRAGDKAVEIYASVAQLSPLDSETLENEANNIK 1290
>M36769-1|AAC17185.1| 1937|Homo sapiens perinatal myosin heavy chain
protein.
Length = 1937
Score = 60.5 bits (140), Expect = 6e-09
Identities = 45/212 (21%), Positives = 105/212 (49%), Gaps = 5/212 (2%)
Frame = +2
Query: 83 TMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 262
T ++ + ++ E + + ++ E++A+ A A + EE+++ Q A +E +
Sbjct: 1729 TKKKLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLER---M 1785
Query: 263 NKNKLEQANKDL-----EEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 427
KN LEQ KDL E ++ L + ++ L +V+++E ++E ++R+ A + L
Sbjct: 1786 KKN-LEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLR 1844
Query: 428 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 607
+ + E + + ++ +D+L ++K + AE+A+ +S+ K ++
Sbjct: 1845 KHDRRVKELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLSKFRKLQH 1904
Query: 608 ELEVAEDRVKSGDAKISXLEXELKVVGNSLKS 703
ELE AE+R +++++ L + + V + +
Sbjct: 1905 ELEEAEERADIAESQVNKLRVKSREVHTKISA 1936
Score = 53.6 bits (123), Expect = 7e-07
Identities = 53/219 (24%), Positives = 102/219 (46%), Gaps = 16/219 (7%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQA-MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQV 244
++K T+ K +Q ++ E D+ D + CEQ ++ ++ E +EV E ++ ++
Sbjct: 877 EEKMVTLLKEKNDLQLQVQSEADSLADAEERCEQLIKN-KIQLEAKIKEVTERAEEEEEI 935
Query: 245 EEDLILNKNKLE----QANKDLEEKE-------KQLTATEAEVAALNRKVQQIEEDLEK- 388
+L K KLE + KD+++ E KQ ATE +V L ++ ++E + K
Sbjct: 936 NAELTAKKRKLEDECSELKKDIDDLELTLAKVEKQKHATENKVKNLTEEMAGLDETIAKL 995
Query: 389 SEERSG---TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDA 559
S+E+ T QQ L + Q D+ N +L + E+++D L L++ + L D
Sbjct: 996 SKEKKALQETHQQTLDDLQAEEDKVN----ILTKAKTKLEQQVDDLEGSLEQEKKLRMDL 1051
Query: 560 DGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXEL 676
+ ++ L ++ E+ + D K+ E E+
Sbjct: 1052 ERAKRKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEI 1090
Score = 52.4 bits (120), Expect = 2e-06
Identities = 55/221 (24%), Positives = 98/221 (44%), Gaps = 7/221 (3%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
+++ +A+ +Q+ + + D ++ + ++ + K N EV + + K E
Sbjct: 1323 EEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKY---E 1379
Query: 248 EDLILNKNKLEQANKDL----EEKEKQLTATEAEVAALNRKVQQIE---EDLEKSEERSG 406
D I +LE+A K L +E E+ + A A+ A+L + Q+++ EDL ERS
Sbjct: 1380 TDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSN 1439
Query: 407 TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSR 586
A L + Q++ D KVL Q+ EE +L KE+R L+ + +
Sbjct: 1440 AACAALDKKQRNFD------KVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEE 1493
Query: 587 KLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLE 709
L D+LE K+ +IS L ++ G + LE
Sbjct: 1494 SL----DQLETLRRAHKNLQQEISDLTEQIAEGGKQIHELE 1530
Score = 43.6 bits (98), Expect = 7e-04
Identities = 43/180 (23%), Positives = 87/180 (48%)
Frame = +2
Query: 83 TMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 262
T+ + K+ +A++ +D E + K+ ++V +L+ L Q E+ L +
Sbjct: 991 TIAKLSKEKKALQETHQQTLDDLQAEEDKVNILTKAKTKLEQQVDDLEGSLEQ-EKKLRM 1049
Query: 263 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 442
+ LE+A + LE K A E+ + N K QQ++E LEK E K +E +Q+
Sbjct: 1050 D---LERAKRKLEGDLK--LAQESTMDMENDK-QQLDEKLEKKEFEISNLISK-IEDEQA 1102
Query: 443 ADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 622
+ L+ + ++ + R+++L +++ R A+ + ++SR+L + + LE A
Sbjct: 1103 VEIQ------LQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLSRELEEISERLEEA 1156
Score = 42.7 bits (96), Expect = 0.001
Identities = 47/208 (22%), Positives = 98/208 (47%), Gaps = 22/208 (10%)
Frame = +2
Query: 161 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 340
+Q+ D + + +++ EL+K QVE++ + LE+A LE +E ++ + E+
Sbjct: 1509 QQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLEL 1568
Query: 341 ----AALNRKVQQIEED---LEKSEERSGTAQQKLLEAQ-QSADENNRMCKVLENRAQQD 496
+ ++RK+ + +E+ L+++ R Q L+A+ +S ++ R+ K +E +
Sbjct: 1569 NQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEM 1628
Query: 497 EERM--------DQLTNQ------LKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRV 634
E ++ + L N LKE +L +DA +++ +LA VE + + +
Sbjct: 1629 EIQLNHANRLAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEI 1688
Query: 635 KSGDAKISXLEXELKVVGNSLKSLEVSE 718
+ A + E K+ L L+ SE
Sbjct: 1689 EELWATLEQTERSRKIAEQEL--LDASE 1714
Score = 39.9 bits (89), Expect = 0.009
Identities = 28/134 (20%), Positives = 63/134 (47%), Gaps = 7/134 (5%)
Frame = +2
Query: 326 TEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEER 505
TE E+A + + Q+ +++L KSE + ++K++ + ++ + + EER
Sbjct: 848 TEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAEER 907
Query: 506 MDQLTN-------QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXL 664
+QL ++KE AE+ + + E++ K +EDE + + + ++ +
Sbjct: 908 CEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKV 967
Query: 665 EXELKVVGNSLKSL 706
E + N +K+L
Sbjct: 968 EKQKHATENKVKNL 981
Score = 36.7 bits (81), Expect = 0.086
Identities = 37/157 (23%), Positives = 77/157 (49%), Gaps = 7/157 (4%)
Frame = +2
Query: 161 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLE---QANKDLEEKEKQLTATE 331
EQ+ DA+ R + ++ + L ++E D+ ++++E Q +++ EEK K+
Sbjct: 1706 EQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEEKAKKAITDA 1765
Query: 332 AEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMC-KVLENRAQQDEERM 508
A +A +K Q LE+ ++ +Q + + Q DE ++ K + + Q+ E R+
Sbjct: 1766 AMMAEELKKEQDTSAHLERMKK---NLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARV 1822
Query: 509 DQLTNQLK-EARLLAEDADG--KSDEVSRKLAFVEDE 610
+L +++ E + AE G K D ++L + +E
Sbjct: 1823 RELEGEVENEQKRNAEAVKGLRKHDRRVKELTYQTEE 1859
Score = 35.9 bits (79), Expect = 0.15
Identities = 43/210 (20%), Positives = 89/210 (42%), Gaps = 10/210 (4%)
Frame = +2
Query: 110 QAMKLEKDNAMDKADTCEQQA--RDANLRAEKVNEEVRELQKKLAQVEEDL---ILNKN- 271
Q +LEK + + CE QA +A E ++ +Q +L QV+ ++ I K+
Sbjct: 1525 QIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDE 1584
Query: 272 KLEQANKDLEEKEKQLTAT-EAEVAALN---RKVQQIEEDLEKSEERSGTAQQKLLEAQQ 439
+++Q ++ + + +T +AE+ + N R +++E DL + E + A + E+ +
Sbjct: 1585 EIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLAAESLR 1644
Query: 440 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 619
+ + K + + L QL A + +E+ L E ++
Sbjct: 1645 NYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWATLEQTERSRKI 1704
Query: 620 AEDRVKSGDAKISXLEXELKVVGNSLKSLE 709
AE + ++ L + + N+ K LE
Sbjct: 1705 AEQELLDASERVQLLHTQNTSLINTKKKLE 1734
Score = 34.7 bits (76), Expect = 0.35
Identities = 36/188 (19%), Positives = 80/188 (42%), Gaps = 5/188 (2%)
Frame = +2
Query: 161 EQQARDANLRAEKVNEEVRELQKKL-AQVEEDLILNKNKLEQANKDLEEKEKQLTATEAE 337
E+Q D + E+++E + E AQVE LNK + + K + E+ EA
Sbjct: 1136 EKQRSDLSRELEEISERLEEAGGATSAQVE----LNKKREAEFQKLRRDLEEATLQHEAM 1191
Query: 338 VAALNRK----VQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEER 505
VAAL +K + ++ E ++ + +++ E + D+ + + + E+
Sbjct: 1192 VAALRKKHADSMAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGHLEKM 1251
Query: 506 MDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVV 685
L +Q+ + E+ ++++ + A ++ E ++ DA +S L +
Sbjct: 1252 CRSLEDQVSGLKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEQDALVSQLSRSKQAS 1311
Query: 686 GNSLKSLE 709
++ L+
Sbjct: 1312 TQQIEELK 1319
>M27654-1|AAA59489.1| 217|Homo sapiens laminin B2 protein.
Length = 217
Score = 60.5 bits (140), Expect = 6e-09
Identities = 46/172 (26%), Positives = 76/172 (44%), Gaps = 6/172 (3%)
Frame = +2
Query: 182 NLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKV 361
N + NE+ RE Q+ L D KNK +A + +K T+T+AE +V
Sbjct: 3 NQTITEANEKTREAQQALGSAAADATEAKNKAHEAERIASAVQKNATSTKAEAERTFAEV 62
Query: 362 QQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEAR 541
++ ++ ++ A+++L Q AD++ M + AQ+ E + N +
Sbjct: 63 TDLDNEVNNMLKQLQEAEKELKRKQDDADQDMMMAGMASQAAQEAEINARKAKNSVTSLL 122
Query: 542 LLAED---ADGKSDEVS-RKLAFVEDELEVAEDRVKSG--DAKISXLEXELK 679
+ D G+ D V KL +E L A+D +K D K+S LE E K
Sbjct: 123 SIINDLLEQLGQLDTVDLNKLNEIEGTLNKAKDEMKVSDLDRKVSDLENEAK 174
>J03202-1|AAA59488.1| 1609|Homo sapiens LAMB2 protein.
Length = 1609
Score = 60.5 bits (140), Expect = 6e-09
Identities = 46/172 (26%), Positives = 76/172 (44%), Gaps = 6/172 (3%)
Frame = +2
Query: 182 NLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKV 361
N + NE+ RE Q+ L D KNK +A + +K T+T+AE +V
Sbjct: 1395 NQTITEANEKTREAQQALGSAAADATEAKNKAHEAERIASAVQKNATSTKAEAERTFAEV 1454
Query: 362 QQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEAR 541
++ ++ ++ A+++L Q AD++ M + AQ+ E + N +
Sbjct: 1455 TDLDNEVNNMLKQLQEAEKELKRKQDDADQDMMMAGMASQAAQEAEINARKAKNSVTSLL 1514
Query: 542 LLAED---ADGKSDEVS-RKLAFVEDELEVAEDRVKSG--DAKISXLEXELK 679
+ D G+ D V KL +E L A+D +K D K+S LE E K
Sbjct: 1515 SIINDLLEQLGQLDTVDLNKLNEIEGTLNKAKDEMKVSDLDRKVSDLENEAK 1566
Score = 48.4 bits (110), Expect = 3e-05
Identities = 51/219 (23%), Positives = 89/219 (40%), Gaps = 7/219 (3%)
Frame = +2
Query: 71 QKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEE 250
QK + +++ M+ +LE N ++K T +Q A RA+ E KK
Sbjct: 1302 QKLKDYEDLREDMRGKELEVKNLLEKGKTEQQTADQLLARADAAKALAEEAAKK----GR 1357
Query: 251 DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLE 430
D + N + KD + + T AE A RK+ I + + ++ E++ AQQ L
Sbjct: 1358 DTLQEANDILNNLKDFDRRVND-NKTAAEEAL--RKIPAINQTITEANEKTREAQQALGS 1414
Query: 431 AQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDE 610
A A E E A ++ + + D D + + + ++L E E
Sbjct: 1415 AAADATEAKNKAHEAERIASAVQKNATSTKAEAERTFAEVTDLDNEVNNMLKQLQEAEKE 1474
Query: 611 L-----EVAEDRVKSGDAKISXLEXEL--KVVGNSLKSL 706
L + +D + +G A + E E+ + NS+ SL
Sbjct: 1475 LKRKQDDADQDMMMAGMASQAAQEAEINARKAKNSVTSL 1513
Score = 37.5 bits (83), Expect = 0.049
Identities = 29/141 (20%), Positives = 57/141 (40%), Gaps = 2/141 (1%)
Frame = +2
Query: 143 DKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLT 322
D+ E++ D A+ V + + L +L +V L ++L+ +EE
Sbjct: 1073 DRLKEAEREVMDLLREAQDVKDVDQNLMDRLQRVNNTLSSQISRLQNIRNTIEETGNLAE 1132
Query: 323 ATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENR--AQQD 496
A V R ++ +LEK+ + A + + + + D NN E R A++
Sbjct: 1133 QARAHVENTERLIEIASRELEKA--KVAAANVSVTQPESTGDPNNMTLLAEEARKLAERH 1190
Query: 497 EERMDQLTNQLKEARLLAEDA 559
++ D + K A + +A
Sbjct: 1191 KQEADDIVRVAKTANDTSTEA 1211
Score = 34.3 bits (75), Expect = 0.46
Identities = 48/224 (21%), Positives = 100/224 (44%), Gaps = 18/224 (8%)
Frame = +2
Query: 83 TMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 262
T A + +++ + E + + +A + ++ R ++VN + +L + +
Sbjct: 1067 TDQAFEDRLKEAEREVMDLLREAQDVKDVDQNLMDRLQRVNNTLSSQISRLQNIRNTIEE 1126
Query: 263 NKNKLEQANKDLEEKEK--QLTATE---AEVAALNRKVQQIEEDLEKSE-ERSGTAQQKL 424
N EQA +E E+ ++ + E A+VAA N V Q E + + +KL
Sbjct: 1127 TGNLAEQARAHVENTERLIEIASRELEKAKVAAANVSVTQPESTGDPNNMTLLAEEARKL 1186
Query: 425 LEA-QQSADENNRMCKVLENRAQQDEERM-------DQLTNQLKEARLLAEDADGKSDEV 580
E +Q AD+ R+ K + + + + +Q +++E E A S ++
Sbjct: 1187 AERHKQEADDIVRVAKTANDTSTEAYNLLLRTLAGENQTAFEIEELNRKYEQAKNISQDL 1246
Query: 581 SRKLAFVEDELEVAEDR---VKSGDAKISXLEXE-LKVVGNSLK 700
++ A V +E + A D+ + + A++S L+ E L+ N++K
Sbjct: 1247 EKQAARVHEEAKRAGDKAVEIYASVAQLSPLDSETLENEANNIK 1290
>AL450304-5|CAI14877.1| 1609|Homo sapiens laminin, gamma 1 (formerly
LAMB2) protein.
Length = 1609
Score = 60.5 bits (140), Expect = 6e-09
Identities = 46/172 (26%), Positives = 76/172 (44%), Gaps = 6/172 (3%)
Frame = +2
Query: 182 NLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKV 361
N + NE+ RE Q+ L D KNK +A + +K T+T+AE +V
Sbjct: 1395 NQTITEANEKTREAQQALGSAAADATEAKNKAHEAERIASAVQKNATSTKAEAERTFAEV 1454
Query: 362 QQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEAR 541
++ ++ ++ A+++L Q AD++ M + AQ+ E + N +
Sbjct: 1455 TDLDNEVNNMLKQLQEAEKELKRKQDDADQDMMMAGMASQAAQEAEINARKAKNSVTSLL 1514
Query: 542 LLAED---ADGKSDEVS-RKLAFVEDELEVAEDRVKSG--DAKISXLEXELK 679
+ D G+ D V KL +E L A+D +K D K+S LE E K
Sbjct: 1515 SIINDLLEQLGQLDTVDLNKLNEIEGTLNKAKDEMKVSDLDRKVSDLENEAK 1566
Score = 48.4 bits (110), Expect = 3e-05
Identities = 51/219 (23%), Positives = 89/219 (40%), Gaps = 7/219 (3%)
Frame = +2
Query: 71 QKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEE 250
QK + +++ M+ +LE N ++K T +Q A RA+ E KK
Sbjct: 1302 QKLKDYEDLREDMRGKELEVKNLLEKGKTEQQTADQLLARADAAKALAEEAAKK----GR 1357
Query: 251 DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLE 430
D + N + KD + + T AE A RK+ I + + ++ E++ AQQ L
Sbjct: 1358 DTLQEANDILNNLKDFDRRVND-NKTAAEEAL--RKIPAINQTITEANEKTREAQQALGS 1414
Query: 431 AQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDE 610
A A E E A ++ + + D D + + + ++L E E
Sbjct: 1415 AAADATEAKNKAHEAERIASAVQKNATSTKAEAERTFAEVTDLDNEVNNMLKQLQEAEKE 1474
Query: 611 L-----EVAEDRVKSGDAKISXLEXEL--KVVGNSLKSL 706
L + +D + +G A + E E+ + NS+ SL
Sbjct: 1475 LKRKQDDADQDMMMAGMASQAAQEAEINARKAKNSVTSL 1513
Score = 37.5 bits (83), Expect = 0.049
Identities = 29/141 (20%), Positives = 57/141 (40%), Gaps = 2/141 (1%)
Frame = +2
Query: 143 DKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLT 322
D+ E++ D A+ V + + L +L +V L ++L+ +EE
Sbjct: 1073 DRLKEAEREVMDLLREAQDVKDVDQNLMDRLQRVNNTLSSQISRLQNIRNTIEETGNLAE 1132
Query: 323 ATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENR--AQQD 496
A V R ++ +LEK+ + A + + + + D NN E R A++
Sbjct: 1133 QARAHVENTERLIEIASRELEKA--KVAAANVSVTQPESTGDPNNMTLLAEEARKLAERH 1190
Query: 497 EERMDQLTNQLKEARLLAEDA 559
++ D + K A + +A
Sbjct: 1191 KQEADDIVRVAKTANDTSTEA 1211
Score = 34.3 bits (75), Expect = 0.46
Identities = 48/224 (21%), Positives = 100/224 (44%), Gaps = 18/224 (8%)
Frame = +2
Query: 83 TMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 262
T A + +++ + E + + +A + ++ R ++VN + +L + +
Sbjct: 1067 TDQAFEDRLKEAEREVMDLLREAQDVKDVDQNLMDRLQRVNNTLSSQISRLQNIRNTIEE 1126
Query: 263 NKNKLEQANKDLEEKEK--QLTATE---AEVAALNRKVQQIEEDLEKSE-ERSGTAQQKL 424
N EQA +E E+ ++ + E A+VAA N V Q E + + +KL
Sbjct: 1127 TGNLAEQARAHVENTERLIEIASRELEKAKVAAANVSVTQPESTGDPNNMTLLAEEARKL 1186
Query: 425 LEA-QQSADENNRMCKVLENRAQQDEERM-------DQLTNQLKEARLLAEDADGKSDEV 580
E +Q AD+ R+ K + + + + +Q +++E E A S ++
Sbjct: 1187 AERHKQEADDIVRVAKTANDTSTEAYNLLLRTLAGENQTAFEIEELNRKYEQAKNISQDL 1246
Query: 581 SRKLAFVEDELEVAEDR---VKSGDAKISXLEXE-LKVVGNSLK 700
++ A V +E + A D+ + + A++S L+ E L+ N++K
Sbjct: 1247 EKQAARVHEEAKRAGDKAVEIYASVAQLSPLDSETLENEANNIK 1290
>AL354953-3|CAH70981.1| 1609|Homo sapiens laminin, gamma 1 (formerly
LAMB2) protein.
Length = 1609
Score = 60.5 bits (140), Expect = 6e-09
Identities = 46/172 (26%), Positives = 76/172 (44%), Gaps = 6/172 (3%)
Frame = +2
Query: 182 NLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKV 361
N + NE+ RE Q+ L D KNK +A + +K T+T+AE +V
Sbjct: 1395 NQTITEANEKTREAQQALGSAAADATEAKNKAHEAERIASAVQKNATSTKAEAERTFAEV 1454
Query: 362 QQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEAR 541
++ ++ ++ A+++L Q AD++ M + AQ+ E + N +
Sbjct: 1455 TDLDNEVNNMLKQLQEAEKELKRKQDDADQDMMMAGMASQAAQEAEINARKAKNSVTSLL 1514
Query: 542 LLAED---ADGKSDEVS-RKLAFVEDELEVAEDRVKSG--DAKISXLEXELK 679
+ D G+ D V KL +E L A+D +K D K+S LE E K
Sbjct: 1515 SIINDLLEQLGQLDTVDLNKLNEIEGTLNKAKDEMKVSDLDRKVSDLENEAK 1566
Score = 48.4 bits (110), Expect = 3e-05
Identities = 51/219 (23%), Positives = 89/219 (40%), Gaps = 7/219 (3%)
Frame = +2
Query: 71 QKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEE 250
QK + +++ M+ +LE N ++K T +Q A RA+ E KK
Sbjct: 1302 QKLKDYEDLREDMRGKELEVKNLLEKGKTEQQTADQLLARADAAKALAEEAAKK----GR 1357
Query: 251 DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLE 430
D + N + KD + + T AE A RK+ I + + ++ E++ AQQ L
Sbjct: 1358 DTLQEANDILNNLKDFDRRVND-NKTAAEEAL--RKIPAINQTITEANEKTREAQQALGS 1414
Query: 431 AQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDE 610
A A E E A ++ + + D D + + + ++L E E
Sbjct: 1415 AAADATEAKNKAHEAERIASAVQKNATSTKAEAERTFAEVTDLDNEVNNMLKQLQEAEKE 1474
Query: 611 L-----EVAEDRVKSGDAKISXLEXEL--KVVGNSLKSL 706
L + +D + +G A + E E+ + NS+ SL
Sbjct: 1475 LKRKQDDADQDMMMAGMASQAAQEAEINARKAKNSVTSL 1513
Score = 37.5 bits (83), Expect = 0.049
Identities = 29/141 (20%), Positives = 57/141 (40%), Gaps = 2/141 (1%)
Frame = +2
Query: 143 DKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLT 322
D+ E++ D A+ V + + L +L +V L ++L+ +EE
Sbjct: 1073 DRLKEAEREVMDLLREAQDVKDVDQNLMDRLQRVNNTLSSQISRLQNIRNTIEETGNLAE 1132
Query: 323 ATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENR--AQQD 496
A V R ++ +LEK+ + A + + + + D NN E R A++
Sbjct: 1133 QARAHVENTERLIEIASRELEKA--KVAAANVSVTQPESTGDPNNMTLLAEEARKLAERH 1190
Query: 497 EERMDQLTNQLKEARLLAEDA 559
++ D + K A + +A
Sbjct: 1191 KQEADDIVRVAKTANDTSTEA 1211
Score = 34.3 bits (75), Expect = 0.46
Identities = 48/224 (21%), Positives = 100/224 (44%), Gaps = 18/224 (8%)
Frame = +2
Query: 83 TMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 262
T A + +++ + E + + +A + ++ R ++VN + +L + +
Sbjct: 1067 TDQAFEDRLKEAEREVMDLLREAQDVKDVDQNLMDRLQRVNNTLSSQISRLQNIRNTIEE 1126
Query: 263 NKNKLEQANKDLEEKEK--QLTATE---AEVAALNRKVQQIEEDLEKSE-ERSGTAQQKL 424
N EQA +E E+ ++ + E A+VAA N V Q E + + +KL
Sbjct: 1127 TGNLAEQARAHVENTERLIEIASRELEKAKVAAANVSVTQPESTGDPNNMTLLAEEARKL 1186
Query: 425 LEA-QQSADENNRMCKVLENRAQQDEERM-------DQLTNQLKEARLLAEDADGKSDEV 580
E +Q AD+ R+ K + + + + +Q +++E E A S ++
Sbjct: 1187 AERHKQEADDIVRVAKTANDTSTEAYNLLLRTLAGENQTAFEIEELNRKYEQAKNISQDL 1246
Query: 581 SRKLAFVEDELEVAEDR---VKSGDAKISXLEXE-LKVVGNSLK 700
++ A V +E + A D+ + + A++S L+ E L+ N++K
Sbjct: 1247 EKQAARVHEEAKRAGDKAVEIYASVAQLSPLDSETLENEANNIK 1290
>AF111783-1|AAD29949.1| 1939|Homo sapiens myosin heavy chain IIb
protein.
Length = 1939
Score = 60.1 bits (139), Expect = 8e-09
Identities = 54/219 (24%), Positives = 111/219 (50%), Gaps = 10/219 (4%)
Frame = +2
Query: 83 TMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 262
T ++ + ++ E ++ + +A E++A+ A A + EE+++ Q A +E +
Sbjct: 1730 TKKKLETDISQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLER---M 1786
Query: 263 NKNKLEQANKDLEEKEKQLTATEAEVAALN---RKVQQIEEDLEKSEERSGTAQQKLLEA 433
KN +EQ KDL QL EAE AL +++Q++E + + E + Q+ +EA
Sbjct: 1787 KKN-MEQTVKDL-----QLRLGEAEQLALKGGKKQIQKLEARVRELESEVESEQKHNVEA 1840
Query: 434 QQSADENNRMCKVLENRAQQD-------EERMDQLTNQLKEARLLAEDADGKSDEVSRKL 592
+ ++ R K L + ++D ++ +D+L ++K + AE+A+ +S+ K
Sbjct: 1841 VKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQTKVKAYKRQAEEAEEQSNVNLAKF 1900
Query: 593 AFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLE 709
++ ELE AE+R +++++ L + + V + S E
Sbjct: 1901 RKLQHELEEAEERADIAESQVNKLRVKSREVHTKVISEE 1939
Score = 54.4 bits (125), Expect = 4e-07
Identities = 44/211 (20%), Positives = 96/211 (45%), Gaps = 6/211 (2%)
Frame = +2
Query: 95 IKKKMQA---MKLEKDNAMDKAD-TCEQQARDANLRAE--KVNEEVRELQKKLAQVEEDL 256
IK K+Q +K + A D+ + E A+ L E ++ +++ +L+ LA+VE++
Sbjct: 913 IKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEK 972
Query: 257 ILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQ 436
+NK++ +++ ++ + E AL QQ +DL+ E++ T + + +
Sbjct: 973 HATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEEDKVNTLTKAKTKLE 1032
Query: 437 QSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELE 616
Q D+ + + E +L LK A+ D + +++ KL E E+
Sbjct: 1033 QQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMDTENDKQQLNEKLKKKEFEMS 1092
Query: 617 VAEDRVKSGDAKISXLEXELKVVGNSLKSLE 709
+ +++ A L+ ++K + ++ LE
Sbjct: 1093 NLQGKIEDEQALAMQLQKKIKELQARIEELE 1123
Score = 45.6 bits (103), Expect = 2e-04
Identities = 31/134 (23%), Positives = 63/134 (47%), Gaps = 7/134 (5%)
Frame = +2
Query: 326 TEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEER 505
TE E+A + + ++ +E+L K+E + ++K++ Q ++ + + EER
Sbjct: 849 TEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADALADAEER 908
Query: 506 MDQLTN-------QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXL 664
DQL ++KE AED + + E++ K +EDE + + + ++ +
Sbjct: 909 CDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKV 968
Query: 665 EXELKVVGNSLKSL 706
E E N +K+L
Sbjct: 969 EKEKHATENKVKNL 982
Score = 45.6 bits (103), Expect = 2e-04
Identities = 53/188 (28%), Positives = 81/188 (43%), Gaps = 5/188 (2%)
Frame = +2
Query: 161 EQQARDANLRA-EKVNEEVRELQKKLA----QVEEDLILNKNKLEQANKDLEEKEKQLTA 325
EQ+A+ R K N EV + + K Q E+L K KL Q +D EE + + +
Sbjct: 1354 EQEAKAELQRGMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNS 1413
Query: 326 TEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEER 505
A + +++Q EDL ERS A L + Q++ D KVL Q+ EE
Sbjct: 1414 KCASLEKTKQRLQNEVEDLMIDVERSNAACIALDKKQRNFD------KVLAEWKQKYEET 1467
Query: 506 MDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVV 685
+L KE+R L+ + + L D LE + K+ +IS L ++
Sbjct: 1468 QAELEASQKESRSLSTELFKVKNAYEESL----DHLETLKRENKNLQQEISDLTEQIAEG 1523
Query: 686 GNSLKSLE 709
G + LE
Sbjct: 1524 GKHIHELE 1531
Score = 38.7 bits (86), Expect = 0.021
Identities = 44/214 (20%), Positives = 92/214 (42%), Gaps = 16/214 (7%)
Frame = +2
Query: 80 ATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLI 259
+TMD K Q + K + ++ + + D A ++ ++++ELQ ++ ++EE++
Sbjct: 1069 STMDTENDKQQLNEKLKKKEFEMSNL-QGKIEDEQALAMQLQKKIKELQARIEELEEEIE 1127
Query: 260 LNKNKLEQANK-------DLEEKEKQLT----ATEAEVAALNRK----VQQIEEDLEKSE 394
+ +A K +LEE ++L AT A++ LN+K Q++ DLE+S
Sbjct: 1128 AERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQI-ELNKKREAEFQKMRRDLEEST 1186
Query: 395 -ERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKS 571
+ TA + S E + L+ Q+ E+ +L ++ + E
Sbjct: 1187 LQHEATAAALRKKHADSVAELGKQIDSLQRVKQKLEKEKSELKMEINDLASNMETVSKAK 1246
Query: 572 DEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXE 673
+ +ED+L + + + I+ L +
Sbjct: 1247 ANFEKMCRTLEDQLSEIKTKEEEQQRLINELSAQ 1280
Score = 33.1 bits (72), Expect = 1.1
Identities = 43/220 (19%), Positives = 99/220 (45%), Gaps = 15/220 (6%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
+++A M A ++++A LE+ K EQ+ DA+ R + ++ + L ++E
Sbjct: 1679 ERRANLMQAEVEELRA-SLERTERGRKM--AEQELLDASERVQLLHTQNTSLINTKKKLE 1735
Query: 248 EDLILNKNKLE---QANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEK----SEERSG 406
D+ + ++E Q ++ EEK K+ A +A +K Q LE+ E+
Sbjct: 1736 TDISQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVK 1795
Query: 407 TAQQKLLEAQQSADENNR--------MCKVLENRAQQDEERMDQLTNQLKEARLLAEDAD 562
Q +L EA+Q A + + + LE+ + +++ + L++ ++
Sbjct: 1796 DLQLRLGEAEQLALKGGKKQIQKLEARVRELESEVESEQKHNVEAVKGLRKHERRVKELT 1855
Query: 563 GKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKV 682
+++E + + ++D ++ + +VK+ + E + V
Sbjct: 1856 YQTEEDRKNILRLQDLVDKLQTKVKAYKRQAEEAEEQSNV 1895
>BC118982-1|AAI18983.1| 553|Homo sapiens KIAA2012 protein protein.
Length = 553
Score = 58.8 bits (136), Expect = 2e-08
Identities = 53/186 (28%), Positives = 91/186 (48%), Gaps = 13/186 (6%)
Frame = +2
Query: 161 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 340
+++A LRAE+ E++KK + EE L + +LE+A K EE E + E+
Sbjct: 353 QEKASWDRLRAERAEMRWLEVEKKRREQEEQRQLQQEQLERAKKMEEELELEQQRRTEEI 412
Query: 341 AALNRKVQQIEEDLEKSEERSGTAQQKLLE--AQQSADENNRMCKVLENRAQQDE----- 499
+++Q+ E+ ++ EER + K + A+Q +E R + L+ + QQ+E
Sbjct: 413 RLRKQRLQE-EQQRQEEEERKQQLRLKAAQERARQQQEEFRRKLRELQRKKQQEEAERAE 471
Query: 500 ---ERMDQLTNQL-KEARLLAEDADGKSDEVSRKLAFVEDE--LEVAEDRVKSGDAKISX 661
+R ++L QL +E + L E A+ + E R+ E++ LE E R K +A
Sbjct: 472 AEKQRQEELEMQLEEEQKHLMEMAEEERLEYQRRKQEAEEKARLEAEERRQKEEEAARLA 531
Query: 662 LEXELK 679
LE K
Sbjct: 532 LEEATK 537
Score = 40.3 bits (90), Expect = 0.007
Identities = 41/132 (31%), Positives = 62/132 (46%), Gaps = 13/132 (9%)
Frame = +2
Query: 104 KMQAMKLEKDNAMDKADTCEQQAR--DANLRAEKVNEE----VRELQKKLAQVE-EDLIL 262
+++ +L+++ + + +QQ R A RA + EE +RELQ+K Q E E
Sbjct: 413 RLRKQRLQEEQQRQEEEERKQQLRLKAAQERARQQQEEFRRKLRELQRKKQQEEAERAEA 472
Query: 263 NKNKLEQANKDLEEKEKQL-TATEAEVAALNRKVQQIEED--LEKSEER---SGTAQQKL 424
K + E+ LEE++K L E E R+ Q+ EE LE E R A+ L
Sbjct: 473 EKQRQEELEMQLEEEQKHLMEMAEEERLEYQRRKQEAEEKARLEAEERRQKEEEAARLAL 532
Query: 425 LEAQQSADENNR 460
EA + A E R
Sbjct: 533 EEATKQAQEQAR 544
>AB095932-1|BAC23108.1| 555|Homo sapiens KIAA2012 protein protein.
Length = 555
Score = 58.8 bits (136), Expect = 2e-08
Identities = 53/186 (28%), Positives = 91/186 (48%), Gaps = 13/186 (6%)
Frame = +2
Query: 161 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 340
+++A LRAE+ E++KK + EE L + +LE+A K EE E + E+
Sbjct: 355 QEKASWDRLRAERAEMRWLEVEKKRREQEEQRQLQQEQLERAKKMEEELELEQQRRTEEI 414
Query: 341 AALNRKVQQIEEDLEKSEERSGTAQQKLLE--AQQSADENNRMCKVLENRAQQDE----- 499
+++Q+ E+ ++ EER + K + A+Q +E R + L+ + QQ+E
Sbjct: 415 RLRKQRLQE-EQQRQEEEERKQQLRLKAAQERARQQQEEFRRKLRELQRKKQQEEAERAE 473
Query: 500 ---ERMDQLTNQL-KEARLLAEDADGKSDEVSRKLAFVEDE--LEVAEDRVKSGDAKISX 661
+R ++L QL +E + L E A+ + E R+ E++ LE E R K +A
Sbjct: 474 AEKQRQEELEMQLEEEQKHLMEMAEEERLEYQRRKQEAEEKARLEAEERRQKEEEAARLA 533
Query: 662 LEXELK 679
LE K
Sbjct: 534 LEEATK 539
Score = 40.3 bits (90), Expect = 0.007
Identities = 41/132 (31%), Positives = 62/132 (46%), Gaps = 13/132 (9%)
Frame = +2
Query: 104 KMQAMKLEKDNAMDKADTCEQQAR--DANLRAEKVNEE----VRELQKKLAQVE-EDLIL 262
+++ +L+++ + + +QQ R A RA + EE +RELQ+K Q E E
Sbjct: 415 RLRKQRLQEEQQRQEEEERKQQLRLKAAQERARQQQEEFRRKLRELQRKKQQEEAERAEA 474
Query: 263 NKNKLEQANKDLEEKEKQL-TATEAEVAALNRKVQQIEED--LEKSEER---SGTAQQKL 424
K + E+ LEE++K L E E R+ Q+ EE LE E R A+ L
Sbjct: 475 EKQRQEELEMQLEEEQKHLMEMAEEERLEYQRRKQEAEEKARLEAEERRQKEEEAARLAL 534
Query: 425 LEAQQSADENNR 460
EA + A E R
Sbjct: 535 EEATKQAQEQAR 546
>Z97054-3|CAI42646.1| 1233|Homo sapiens structural maintenance of
chromosomes 1A protein.
Length = 1233
Score = 58.4 bits (135), Expect = 2e-08
Identities = 42/165 (25%), Positives = 89/165 (53%), Gaps = 6/165 (3%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQ-QARDANLRAEKVNEEVR---ELQKKL 235
+++ MD ++K+M +++ + ++ + Q Q RD L +V + R E K+
Sbjct: 327 KKRKGDMDELEKEMLSVEKARQEFEERMEEESQSQGRDLTLEENQVKKYHRLKEEASKRA 386
Query: 236 AQVEEDLI-LNKN-KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGT 409
A + ++L N++ K +Q DLEE++K TEA++ R++++ ++ +EK EE T
Sbjct: 387 ATLAQELEKFNRDQKADQDRLDLEERKK--VETEAKIKQKLREIEENQKRIEKLEEYITT 444
Query: 410 AQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL 544
++Q L E ++ E ++ + R + + ++Q+ QL +AR+
Sbjct: 445 SKQSLEEQKKLEGELTEEVEMAKRRIDEINKELNQVMEQLGDARI 489
Score = 46.4 bits (105), Expect = 1e-04
Identities = 41/191 (21%), Positives = 87/191 (45%), Gaps = 18/191 (9%)
Frame = +2
Query: 161 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKL-------EQANKDLEEKEKQL 319
E + N N+E+ + +K++ +VE++L K +L +Q K+++EK+ +L
Sbjct: 232 EVEIEKLNKELASKNKEIEKDKKRMDKVEDELKEKKKELGKMMREQQQIEKEIKEKDSEL 291
Query: 320 TATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDE 499
+ + LE +++ AQ+ + + DE + +E Q+ E
Sbjct: 292 NQKRPQYIKAKENTSHKIKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLSVEKARQEFE 351
Query: 500 ERMDQ--------LT---NQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGD 646
ERM++ LT NQ+K+ L E+A ++ ++++L + + +DR+ +
Sbjct: 352 ERMEEESQSQGRDLTLEENQVKKYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEE 411
Query: 647 AKISXLEXELK 679
K E ++K
Sbjct: 412 RKKVETEAKIK 422
Score = 42.3 bits (95), Expect = 0.002
Identities = 32/171 (18%), Positives = 84/171 (49%), Gaps = 1/171 (0%)
Frame = +2
Query: 128 KDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEK 307
K N + +Q+ +A+ R +++ +EV Q +L + L N+ ++E+ NK+L K
Sbjct: 189 KKNIAAERKEAKQEKEEAD-RYQRLKDEVVRAQVQLQLFK--LYHNEVEIEKLNKELASK 245
Query: 308 EKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENN-RMCKVLENR 484
K++ + + + ++++ +++L K ++++ E ++ + K EN
Sbjct: 246 NKEIEKDKKRMDKVEDELKEKKKELGKMMREQQQIEKEIKEKDSELNQKRPQYIKAKENT 305
Query: 485 AQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVK 637
+ + ++++ L+ A+ + G DE+ +++ VE + E+R++
Sbjct: 306 SHK-IKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLSVEKARQEFEERME 355
Score = 40.3 bits (90), Expect = 0.007
Identities = 37/203 (18%), Positives = 95/203 (46%), Gaps = 13/203 (6%)
Frame = +2
Query: 98 KKKMQAMKLEKDNA--MDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN 271
+K+ Q +K +++ + + K + ++ ++A +K ++ EL+K++ VE+ +
Sbjct: 293 QKRPQYIKAKENTSHKIKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLSVEKARQEFEE 352
Query: 272 KLEQAN----KDLEEKEKQL-------TATEAEVAALNRKVQQIEEDLEKSEERSGTAQQ 418
++E+ + +DL +E Q+ A L +++++ D + ++R ++
Sbjct: 353 RMEEESQSQGRDLTLEENQVKKYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEER 412
Query: 419 KLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAF 598
K +E + + R + + R ++ EE + L+E + L + + + R++
Sbjct: 413 KKVETEAKIKQKLREIEENQKRIEKLEEYITTSKQSLEEQKKLEGELTEEVEMAKRRIDE 472
Query: 599 VEDELEVAEDRVKSGDAKISXLE 667
+ EL +++ GDA+I E
Sbjct: 473 INKELNQVMEQL--GDARIDRQE 493
Score = 34.3 bits (75), Expect = 0.46
Identities = 34/175 (19%), Positives = 85/175 (48%), Gaps = 4/175 (2%)
Frame = +2
Query: 188 RAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQ 367
R+ ++ +E + +K++ + EED N ++ + N E KE + EA+ + Q+
Sbjct: 160 RSGELAQEYDKRKKEMVKAEEDTQFNYHR--KKNIAAERKEAKQEKEEAD------RYQR 211
Query: 368 IEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLL 547
+++++ +++ + KL + ++ N+ ++D++RMD++ ++LKE +
Sbjct: 212 LKDEVVRAQVQLQLF--KLYHNEVEIEKLNKELASKNKEIEKDKKRMDKVEDELKEKKKE 269
Query: 548 AEDADGKSDEVSRKLAFVEDELEVAEDR-VKSGD---AKISXLEXELKVVGNSLK 700
+ ++ +++ + EL + +K+ + KI LE K + N+ K
Sbjct: 270 LGKMMREQQQIEKEIKEKDSELNQKRPQYIKAKENTSHKIKKLEAAKKSLQNAQK 324
Score = 33.9 bits (74), Expect = 0.60
Identities = 44/224 (19%), Positives = 95/224 (42%), Gaps = 11/224 (4%)
Frame = +2
Query: 86 MDAIKKKMQAMKLEKDNAMDKADTCEQQAR--DANLRAE-----KVNEEVRELQKKLAQV 244
MD ++ +++ K E M + E++ + D+ L + K E KKL
Sbjct: 256 MDKVEDELKEKKKELGKMMREQQQIEKEIKEKDSELNQKRPQYIKAKENTSHKIKKLEAA 315
Query: 245 EEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL 424
++ L + ++ D++E EK++ + E + Q+ EE +E EE +
Sbjct: 316 KKSLQNAQKHYKKRKGDMDELEKEMLSVE-------KARQEFEERME--EESQSQGRDLT 366
Query: 425 LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVE 604
LE Q + +R+ + RA + +++ K + + + K E K+
Sbjct: 367 LEENQ-VKKYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEERKKVETEAKIKQKL 425
Query: 605 DELEVAEDRVKSGDAKIS----XLEXELKVVGNSLKSLEVSEXK 724
E+E + R++ + I+ LE + K+ G + +E+++ +
Sbjct: 426 REIEENQKRIEKLEEYITTSKQSLEEQKKLEGELTEEVEMAKRR 469
Score = 31.1 bits (67), Expect = 4.3
Identities = 37/199 (18%), Positives = 83/199 (41%), Gaps = 14/199 (7%)
Frame = +2
Query: 86 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKL-------AQV 244
++ +KK+ Q D M + + Q N E+ E++KKL +
Sbjct: 849 IEKLKKEEQRHMKIIDETMAQLQDLKNQHLAKKSEVNDKNHEMEEIRKKLGGANKEMTHL 908
Query: 245 EEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQI--EEDLEKSEER-SGTAQ 415
++++ + KLEQ D + + ++ + I EE + E+ SG+ +
Sbjct: 909 QKEVTAIETKLEQKRSDRHNLLQACKMQDIKLPLSKGTMDDISQEEGSSQGEDSVSGSQR 968
Query: 416 QKLLEAQQSADE--NNRMCKVLENRAQQDE--ERMDQLTNQLKEARLLAEDADGKSDEVS 583
+ A+++ E +C+ L++ ++E + M+ L +L E + + + + +
Sbjct: 969 ISSIYAREALIEIDYGDLCEDLKDAQAEEEIKQEMNTLQQKLNEQQSVLQRIAAPNMKAM 1028
Query: 584 RKLAFVEDELEVAEDRVKS 640
KL V D+ + D ++
Sbjct: 1029 EKLESVRDKFQETSDEFEA 1047
>X51593-1|CAA35942.1| 1085|Homo sapiens embryonic myosin heavy chain
(1085 AA) protein.
Length = 1085
Score = 58.4 bits (135), Expect = 2e-08
Identities = 47/217 (21%), Positives = 107/217 (49%), Gaps = 5/217 (2%)
Frame = +2
Query: 83 TMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 262
T ++ + ++ E ++A A E++A+ A A + EE+++ Q A +E +
Sbjct: 872 TKKKLETDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLER---M 928
Query: 263 NKNKLEQANKDL-----EEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 427
KN LEQ KDL E ++ L + ++ L +++++E +LE ++++ + + L
Sbjct: 929 KKN-LEQTVKDLQHRLDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLR 987
Query: 428 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 607
+ ++ E + + ++ +D+L ++K + AE+AD +++ K +
Sbjct: 988 KYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKVKSYKRQAEEADEQANAHLTKFRKAQH 1047
Query: 608 ELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSE 718
ELE AE+R +++++ L + + +S + SE
Sbjct: 1048 ELEEAEERADIAESQVNKLRAKTRDFTSSRMVVHESE 1084
Score = 50.0 bits (114), Expect = 9e-06
Identities = 47/223 (21%), Positives = 104/223 (46%), Gaps = 19/223 (8%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQA-MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQV 244
++K T+ K +Q ++ E +N +D + C+Q + A + E +EV E + ++
Sbjct: 20 EEKLVTLVQEKNDLQLQVQAESENLLDAEERCDQLIK-AKFQLEAKIKEVTERAEDEEEI 78
Query: 245 EEDLILNKNKLE----QANKDLEEKE-------KQLTATEAEVAALNRKVQQIEEDLEK- 388
+L K KLE + KD+++ E K+ ATE +V L ++ ++E + K
Sbjct: 79 NAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEELSGLDETIAKL 138
Query: 389 SEERSG--TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAE--- 553
+ E+ A Q+ L+ Q+ ++ +++ +Q E ++ Q K+ R+ E
Sbjct: 139 TREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNK 198
Query: 554 -DADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELK 679
+G + +E++ + ++R+K D + L+ +++
Sbjct: 199 RKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQLQSKVE 241
Score = 48.0 bits (109), Expect = 3e-05
Identities = 37/216 (17%), Positives = 96/216 (44%), Gaps = 1/216 (0%)
Frame = +2
Query: 86 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 265
+D + M+++ K N T E Q +A + E++ + EL + ++++ +
Sbjct: 374 IDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEA--- 430
Query: 266 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 445
+ ++ LEEKE ++ A ++ ++++ LE+ + L ++
Sbjct: 431 ----GELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALGHALQSSRHDC 486
Query: 446 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAE-DADGKSDEVSRKLAFVEDELEVA 622
D + + + + + + +++ + R E DA +++E+ + L+ +
Sbjct: 487 DLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDS 546
Query: 623 EDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXKAN 730
E++V++ +AK + LE + + ++ L V +AN
Sbjct: 547 EEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERAN 582
Score = 46.4 bits (105), Expect = 1e-04
Identities = 51/226 (22%), Positives = 104/226 (46%), Gaps = 14/226 (6%)
Frame = +2
Query: 71 QKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEE 250
++A + I ++ A K + + D+ ++ D L KV +E + K+ + E
Sbjct: 70 ERAEDEEEINAELTAKKRKLE---DECSELKKDIDDLELTLAKVEKEKHATENKVKNLTE 126
Query: 251 DLI-LNKN--KLEQANKDLEEKEKQ----LTATEAEVAALNR---KVQQIEEDLEKSEER 400
+L L++ KL + K L+E +Q L A E +V +LN+ K++Q EDLE S E+
Sbjct: 127 ELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQ 186
Query: 401 SGTAQQKLLEAQQSADENNRMCKV----LENRAQQDEERMDQLTNQLKEARLLAEDADGK 568
+ L ++ + + ++ + LEN QQ +ER+ + + + + ED
Sbjct: 187 EKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTL 246
Query: 569 SDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSL 706
+ +K+ ++ +E E+ +++ A + E + L+ L
Sbjct: 247 GLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEEL 292
Score = 45.6 bits (103), Expect = 2e-04
Identities = 30/153 (19%), Positives = 74/153 (48%)
Frame = +2
Query: 164 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 343
QQA D +L+AE+ ++V L K +++E+ + ++ LEQ K + E+ E ++
Sbjct: 150 QQALD-DLQAEE--DKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLK 206
Query: 344 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 523
+ +E D ++ +ER + + Q ++ + + + ++ + R+++L
Sbjct: 207 LAQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEE 266
Query: 524 QLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 622
+++ R + + + +R+L + + LE A
Sbjct: 267 EIEAERATRAKTEKQRSDYARELEELSERLEEA 299
Score = 45.6 bits (103), Expect = 2e-04
Identities = 46/201 (22%), Positives = 95/201 (47%), Gaps = 22/201 (10%)
Frame = +2
Query: 161 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 340
EQ+ D + + + + EL+K Q+E + + LE+A LE +E ++ + E+
Sbjct: 652 EQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHEEAKILRIQLEL 711
Query: 341 ----AALNRKVQQIEEDLE---KSEERSGTAQQKLLEAQ-QSADENNRMCKVLE------ 478
+ ++RK+ + +E++E ++ +R+ Q L+A+ + A+E R+ K +E
Sbjct: 712 TQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRRANEAIRLKKKMEGDLNEI 771
Query: 479 -------NR-AQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRV 634
NR A + + + + QLK+ +L +DA +++ +LA VE + + V
Sbjct: 772 EIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEV 831
Query: 635 KSGDAKISXLEXELKVVGNSL 697
+ A + E K+ L
Sbjct: 832 EELRATLEQTERARKLAEQEL 852
Score = 39.5 bits (88), Expect = 0.012
Identities = 36/185 (19%), Positives = 89/185 (48%), Gaps = 4/185 (2%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
+++A + A ++++A + + A A EQ+ D+N R + ++ + L ++E
Sbjct: 821 ERRANLLQAEVEELRATLEQTERARKLA---EQELLDSNERVQLLHTQNTSLIHTKKKLE 877
Query: 248 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 427
DL+ ++++E A++D E++ + A + ++++ ++ E +Q +
Sbjct: 878 TDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVK 937
Query: 428 EAQQSADENNRMC-KVLENRAQQDEERMDQLTNQLK-EARLLAEDADG--KSDEVSRKLA 595
+ Q DE ++ K + + Q+ E R+ +L +L+ E + E G K + ++L
Sbjct: 938 DLQHRLDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRKYERRVKELT 997
Query: 596 FVEDE 610
+ +E
Sbjct: 998 YQSEE 1002
Score = 39.1 bits (87), Expect = 0.016
Identities = 29/122 (23%), Positives = 55/122 (45%), Gaps = 7/122 (5%)
Frame = +2
Query: 362 QQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN------ 523
Q+ +++L KSE + ++KL+ Q ++ + EER DQL
Sbjct: 3 QKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEERCDQLIKAKFQLE 62
Query: 524 -QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLK 700
++KE AED + + E++ K +EDE + + + ++ +E E N +K
Sbjct: 63 AKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVK 122
Query: 701 SL 706
+L
Sbjct: 123 NL 124
Score = 34.7 bits (76), Expect = 0.35
Identities = 37/175 (21%), Positives = 84/175 (48%), Gaps = 3/175 (1%)
Frame = +2
Query: 161 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 340
+++ ++ R E++ EE+ + A+ E+ +LE+ ++ LEE +T+T+ E
Sbjct: 251 QKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERLEE-AGGVTSTQIE- 308
Query: 341 AALNRKVQQIEEDLEKSEERSGTAQQKLLEA---QQSADENNRMCKVLENRAQQDEERMD 511
LN+K + L + E + T Q + + A ++ AD + + ++N Q+ +++++
Sbjct: 309 --LNKKREAEFLKLRRDLEEA-TLQHEAMVATLRKKHADSVAELGEQIDN-LQRVKQKLE 364
Query: 512 QLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXEL 676
+ + E +L +D + VS+ A +E ED++ K ++ L
Sbjct: 365 K---EKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSL 416
>X15696-1|CAA33731.1| 1085|Homo sapiens protein ( Human muscle mRNA
for embryonic myosin heavy chain (SMHCE). ).
Length = 1085
Score = 58.4 bits (135), Expect = 2e-08
Identities = 47/217 (21%), Positives = 107/217 (49%), Gaps = 5/217 (2%)
Frame = +2
Query: 83 TMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 262
T ++ + ++ E ++A A E++A+ A A + EE+++ Q A +E +
Sbjct: 872 TKKKLETDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLER---M 928
Query: 263 NKNKLEQANKDL-----EEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 427
KN LEQ KDL E ++ L + ++ L +++++E +LE ++++ + + L
Sbjct: 929 KKN-LEQTVKDLQHRLDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLR 987
Query: 428 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 607
+ ++ E + + ++ +D+L ++K + AE+AD +++ K +
Sbjct: 988 KYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKVKSYKRQAEEADEQANAHLTKFRKAQH 1047
Query: 608 ELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSE 718
ELE AE+R +++++ L + + +S + SE
Sbjct: 1048 ELEEAEERADIAESQVNKLRAKTRDFTSSRMVVHESE 1084
Score = 50.0 bits (114), Expect = 9e-06
Identities = 47/223 (21%), Positives = 104/223 (46%), Gaps = 19/223 (8%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQA-MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQV 244
++K T+ K +Q ++ E +N +D + C+Q + A + E +EV E + ++
Sbjct: 20 EEKLVTLVQEKNDLQLQVQAESENLLDAEERCDQLIK-AKFQLEAKIKEVTERAEDEEEI 78
Query: 245 EEDLILNKNKLE----QANKDLEEKE-------KQLTATEAEVAALNRKVQQIEEDLEK- 388
+L K KLE + KD+++ E K+ ATE +V L ++ ++E + K
Sbjct: 79 NAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEELSGLDETIAKL 138
Query: 389 SEERSG--TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAE--- 553
+ E+ A Q+ L+ Q+ ++ +++ +Q E ++ Q K+ R+ E
Sbjct: 139 TREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNK 198
Query: 554 -DADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELK 679
+G + +E++ + ++R+K D + L+ +++
Sbjct: 199 RKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQLQSKVE 241
Score = 48.8 bits (111), Expect = 2e-05
Identities = 45/223 (20%), Positives = 105/223 (47%), Gaps = 8/223 (3%)
Frame = +2
Query: 86 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 265
+D + M+++ K N T E Q +A + E++ + EL + ++++ +
Sbjct: 374 IDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEA--- 430
Query: 266 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 445
+ ++ LEEKE ++ A ++ ++++ LE+ + A+ L A QS+
Sbjct: 431 ----GELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENK----AKNALAHALQSS 482
Query: 446 DENNRMCKVLENRAQQDEERMDQLTNQLKEARL-LAE-------DADGKSDEVSRKLAFV 601
+ C +L + ++++E +L L +A +A+ DA +++E+ +
Sbjct: 483 RHD---CDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKL 539
Query: 602 EDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXKAN 730
L+ +E++V++ +AK + LE + + ++ L V +AN
Sbjct: 540 AQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERAN 582
Score = 46.4 bits (105), Expect = 1e-04
Identities = 51/226 (22%), Positives = 104/226 (46%), Gaps = 14/226 (6%)
Frame = +2
Query: 71 QKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEE 250
++A + I ++ A K + + D+ ++ D L KV +E + K+ + E
Sbjct: 70 ERAEDEEEINAELTAKKRKLE---DECSELKKDIDDLELTLAKVEKEKHATENKVKNLTE 126
Query: 251 DLI-LNKN--KLEQANKDLEEKEKQ----LTATEAEVAALNR---KVQQIEEDLEKSEER 400
+L L++ KL + K L+E +Q L A E +V +LN+ K++Q EDLE S E+
Sbjct: 127 ELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQ 186
Query: 401 SGTAQQKLLEAQQSADENNRMCKV----LENRAQQDEERMDQLTNQLKEARLLAEDADGK 568
+ L ++ + + ++ + LEN QQ +ER+ + + + + ED
Sbjct: 187 EKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTL 246
Query: 569 SDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSL 706
+ +K+ ++ +E E+ +++ A + E + L+ L
Sbjct: 247 GLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEEL 292
Score = 45.6 bits (103), Expect = 2e-04
Identities = 30/153 (19%), Positives = 74/153 (48%)
Frame = +2
Query: 164 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 343
QQA D +L+AE+ ++V L K +++E+ + ++ LEQ K + E+ E ++
Sbjct: 150 QQALD-DLQAEE--DKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLK 206
Query: 344 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 523
+ +E D ++ +ER + + Q ++ + + + ++ + R+++L
Sbjct: 207 LAQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEE 266
Query: 524 QLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 622
+++ R + + + +R+L + + LE A
Sbjct: 267 EIEAERATRAKTEKQRSDYARELEELSERLEEA 299
Score = 45.6 bits (103), Expect = 2e-04
Identities = 46/201 (22%), Positives = 95/201 (47%), Gaps = 22/201 (10%)
Frame = +2
Query: 161 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 340
EQ+ D + + + + EL+K Q+E + + LE+A LE +E ++ + E+
Sbjct: 652 EQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHEEAKILRIQLEL 711
Query: 341 ----AALNRKVQQIEEDLE---KSEERSGTAQQKLLEAQ-QSADENNRMCKVLE------ 478
+ ++RK+ + +E++E ++ +R+ Q L+A+ +S +E R+ K +E
Sbjct: 712 TQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKKKMEGDLNEI 771
Query: 479 -------NR-AQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRV 634
NR A + + + + QLK+ +L +DA +++ +LA VE + + V
Sbjct: 772 EIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEV 831
Query: 635 KSGDAKISXLEXELKVVGNSL 697
+ A + E K+ L
Sbjct: 832 EELRATLEQTERARKLAEQEL 852
Score = 39.5 bits (88), Expect = 0.012
Identities = 36/185 (19%), Positives = 89/185 (48%), Gaps = 4/185 (2%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
+++A + A ++++A + + A A EQ+ D+N R + ++ + L ++E
Sbjct: 821 ERRANLLQAEVEELRATLEQTERARKLA---EQELLDSNERVQLLHTQNTSLIHTKKKLE 877
Query: 248 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 427
DL+ ++++E A++D E++ + A + ++++ ++ E +Q +
Sbjct: 878 TDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVK 937
Query: 428 EAQQSADENNRMC-KVLENRAQQDEERMDQLTNQLK-EARLLAEDADG--KSDEVSRKLA 595
+ Q DE ++ K + + Q+ E R+ +L +L+ E + E G K + ++L
Sbjct: 938 DLQHRLDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRKYERRVKELT 997
Query: 596 FVEDE 610
+ +E
Sbjct: 998 YQSEE 1002
Score = 39.1 bits (87), Expect = 0.016
Identities = 29/122 (23%), Positives = 55/122 (45%), Gaps = 7/122 (5%)
Frame = +2
Query: 362 QQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN------ 523
Q+ +++L KSE + ++KL+ Q ++ + EER DQL
Sbjct: 3 QKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEERCDQLIKAKFQLE 62
Query: 524 -QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLK 700
++KE AED + + E++ K +EDE + + + ++ +E E N +K
Sbjct: 63 AKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVK 122
Query: 701 SL 706
+L
Sbjct: 123 NL 124
Score = 34.7 bits (76), Expect = 0.35
Identities = 37/175 (21%), Positives = 84/175 (48%), Gaps = 3/175 (1%)
Frame = +2
Query: 161 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 340
+++ ++ R E++ EE+ + A+ E+ +LE+ ++ LEE +T+T+ E
Sbjct: 251 QKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERLEE-AGGVTSTQIE- 308
Query: 341 AALNRKVQQIEEDLEKSEERSGTAQQKLLEA---QQSADENNRMCKVLENRAQQDEERMD 511
LN+K + L + E + T Q + + A ++ AD + + ++N Q+ +++++
Sbjct: 309 --LNKKREAEFLKLRRDLEEA-TLQHEAMVATLRKKHADSVAELGEQIDN-LQRVKQKLE 364
Query: 512 QLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXEL 676
+ + E +L +D + VS+ A +E ED++ K ++ L
Sbjct: 365 K---EKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSL 416
>X13988-1|CAA32167.1| 1940|Homo sapiens protein ( Human mRNA for
embryonic myosin heavy chain. ).
Length = 1940
Score = 58.4 bits (135), Expect = 2e-08
Identities = 47/217 (21%), Positives = 107/217 (49%), Gaps = 5/217 (2%)
Frame = +2
Query: 83 TMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 262
T ++ + ++ E ++A A E++A+ A A + EE+++ Q A +E +
Sbjct: 1727 TKKKLETDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLER---M 1783
Query: 263 NKNKLEQANKDL-----EEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 427
KN LEQ KDL E ++ L + ++ L +++++E +LE ++++ + + L
Sbjct: 1784 KKN-LEQTVKDLQHRLDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLR 1842
Query: 428 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 607
+ ++ E + + ++ +D+L ++K + AE+AD +++ K +
Sbjct: 1843 KYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKVKSYKRQAEEADEQANAHLTKFRKAQH 1902
Query: 608 ELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSE 718
ELE AE+R +++++ L + + +S + SE
Sbjct: 1903 ELEEAEERADIAESQVNKLRAKTRDFTSSRMVVHESE 1939
Score = 50.0 bits (114), Expect = 9e-06
Identities = 47/223 (21%), Positives = 104/223 (46%), Gaps = 19/223 (8%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQA-MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQV 244
++K T+ K +Q ++ E +N +D + C+Q + A + E +EV E + ++
Sbjct: 875 EEKLVTLVQEKNDLQLQVQAESENLLDAEERCDQLIK-AKFQLEAKIKEVTERAEDEEEI 933
Query: 245 EEDLILNKNKLE----QANKDLEEKE-------KQLTATEAEVAALNRKVQQIEEDLEK- 388
+L K KLE + KD+++ E K+ ATE +V L ++ ++E + K
Sbjct: 934 NAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEELSGLDETIAKL 993
Query: 389 SEERSG--TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAE--- 553
+ E+ A Q+ L+ Q+ ++ +++ +Q E ++ Q K+ R+ E
Sbjct: 994 TREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNK 1053
Query: 554 -DADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELK 679
+G + +E++ + ++R+K D + L+ +++
Sbjct: 1054 RKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQLQSKVE 1096
Score = 48.8 bits (111), Expect = 2e-05
Identities = 45/223 (20%), Positives = 105/223 (47%), Gaps = 8/223 (3%)
Frame = +2
Query: 86 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 265
+D + M+++ K N T E Q +A + E++ + EL + ++++ +
Sbjct: 1229 IDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEA--- 1285
Query: 266 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 445
+ ++ LEEKE ++ A ++ ++++ LE+ + A+ L A QS+
Sbjct: 1286 ----GELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENK----AKNALAHALQSS 1337
Query: 446 DENNRMCKVLENRAQQDEERMDQLTNQLKEARL-LAE-------DADGKSDEVSRKLAFV 601
+ C +L + ++++E +L L +A +A+ DA +++E+ +
Sbjct: 1338 RHD---CDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAQEKL 1394
Query: 602 EDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXKAN 730
L+ +E++V++ +AK + LE + + ++ L V +AN
Sbjct: 1395 AQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERAN 1437
Score = 47.6 bits (108), Expect = 5e-05
Identities = 33/134 (24%), Positives = 62/134 (46%), Gaps = 7/134 (5%)
Frame = +2
Query: 326 TEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEER 505
TE E+A + + Q+ +++L KSE + ++KL+ Q ++ + EER
Sbjct: 846 TEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEER 905
Query: 506 MDQLTN-------QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXL 664
DQL ++KE AED + + E++ K +EDE + + + ++ +
Sbjct: 906 CDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKV 965
Query: 665 EXELKVVGNSLKSL 706
E E N +K+L
Sbjct: 966 EKEKHATENKVKNL 979
Score = 46.4 bits (105), Expect = 1e-04
Identities = 51/226 (22%), Positives = 104/226 (46%), Gaps = 14/226 (6%)
Frame = +2
Query: 71 QKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEE 250
++A + I ++ A K + + D+ ++ D L KV +E + K+ + E
Sbjct: 925 ERAEDEEEINAELTAKKRKLE---DECSELKKDIDDLELTLAKVEKEKHATENKVKNLTE 981
Query: 251 DLI-LNKN--KLEQANKDLEEKEKQ----LTATEAEVAALNR---KVQQIEEDLEKSEER 400
+L L++ KL + K L+E +Q L A E +V +LN+ K++Q EDLE S E+
Sbjct: 982 ELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQ 1041
Query: 401 SGTAQQKLLEAQQSADENNRMCKV----LENRAQQDEERMDQLTNQLKEARLLAEDADGK 568
+ L ++ + + ++ + LEN QQ +ER+ + + + + ED
Sbjct: 1042 EKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTL 1101
Query: 569 SDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSL 706
+ +K+ ++ +E E+ +++ A + E + L+ L
Sbjct: 1102 GLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEEL 1147
Score = 45.6 bits (103), Expect = 2e-04
Identities = 30/153 (19%), Positives = 74/153 (48%)
Frame = +2
Query: 164 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 343
QQA D +L+AE+ ++V L K +++E+ + ++ LEQ K + E+ E ++
Sbjct: 1005 QQALD-DLQAEE--DKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLK 1061
Query: 344 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 523
+ +E D ++ +ER + + Q ++ + + + ++ + R+++L
Sbjct: 1062 LAQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEE 1121
Query: 524 QLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 622
+++ R + + + +R+L + + LE A
Sbjct: 1122 EIEAERATRAKTEKQRSDYARELEELSERLEEA 1154
Score = 45.6 bits (103), Expect = 2e-04
Identities = 46/201 (22%), Positives = 95/201 (47%), Gaps = 22/201 (10%)
Frame = +2
Query: 161 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 340
EQ+ D + + + + EL+K Q+E + + LE+A LE +E ++ + E+
Sbjct: 1507 EQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHEEAKILRIQLEL 1566
Query: 341 ----AALNRKVQQIEEDLE---KSEERSGTAQQKLLEAQ-QSADENNRMCKVLE------ 478
+ ++RK+ + +E++E ++ +R+ Q L+A+ +S +E R+ K +E
Sbjct: 1567 TQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKKKMEGDLNEI 1626
Query: 479 -------NR-AQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRV 634
NR A + + + + QLK+ +L +DA +++ +LA VE + + V
Sbjct: 1627 EIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEV 1686
Query: 635 KSGDAKISXLEXELKVVGNSL 697
+ A + E K+ L
Sbjct: 1687 EELRATLEQTERARKLAEQEL 1707
Score = 39.5 bits (88), Expect = 0.012
Identities = 36/185 (19%), Positives = 89/185 (48%), Gaps = 4/185 (2%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
+++A + A ++++A + + A A EQ+ D+N R + ++ + L ++E
Sbjct: 1676 ERRANLLQAEVEELRATLEQTERARKLA---EQELLDSNERVQLLHTQNTSLIHTKKKLE 1732
Query: 248 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 427
DL+ ++++E A++D E++ + A + ++++ ++ E +Q +
Sbjct: 1733 TDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVK 1792
Query: 428 EAQQSADENNRMC-KVLENRAQQDEERMDQLTNQLK-EARLLAEDADG--KSDEVSRKLA 595
+ Q DE ++ K + + Q+ E R+ +L +L+ E + E G K + ++L
Sbjct: 1793 DLQHRLDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRKYERRVKELT 1852
Query: 596 FVEDE 610
+ +E
Sbjct: 1853 YQSEE 1857
Score = 34.7 bits (76), Expect = 0.35
Identities = 37/175 (21%), Positives = 84/175 (48%), Gaps = 3/175 (1%)
Frame = +2
Query: 161 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 340
+++ ++ R E++ EE+ + A+ E+ +LE+ ++ LEE +T+T+ E
Sbjct: 1106 QKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERLEE-AGGVTSTQIE- 1163
Query: 341 AALNRKVQQIEEDLEKSEERSGTAQQKLLEA---QQSADENNRMCKVLENRAQQDEERMD 511
LN+K + L + E + T Q + + A ++ AD + + ++N Q+ +++++
Sbjct: 1164 --LNKKREAEFLKLRRDLEEA-TLQHEAMVATLRKKHADSVAELGEQIDN-LQRVKQKLE 1219
Query: 512 QLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXEL 676
+ + E +L +D + VS+ A +E ED++ K ++ L
Sbjct: 1220 K---EKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSL 1271
>X13100-1|CAA31492.1| 1167|Homo sapiens myosin heavy chain (1167 AA)
protein.
Length = 1167
Score = 58.4 bits (135), Expect = 2e-08
Identities = 47/217 (21%), Positives = 107/217 (49%), Gaps = 5/217 (2%)
Frame = +2
Query: 83 TMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 262
T ++ + ++ E ++A A E++A+ A A + EE+++ Q A +E +
Sbjct: 954 TKKKLETDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLER---M 1010
Query: 263 NKNKLEQANKDL-----EEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 427
KN LEQ KDL E ++ L + ++ L +++++E +LE ++++ + + L
Sbjct: 1011 KKN-LEQTVKDLQHRLDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLR 1069
Query: 428 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 607
+ ++ E + + ++ +D+L ++K + AE+AD +++ K +
Sbjct: 1070 KYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKVKSYKRQAEEADEQANAHLTKFRKAQH 1129
Query: 608 ELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSE 718
ELE AE+R +++++ L + + +S + SE
Sbjct: 1130 ELEEAEERADIAESQVNKLRAKTRDFTSSRMVVHESE 1166
Score = 50.0 bits (114), Expect = 9e-06
Identities = 47/223 (21%), Positives = 104/223 (46%), Gaps = 19/223 (8%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQA-MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQV 244
++K T+ K +Q ++ E +N +D + C+Q + A + E +EV E + ++
Sbjct: 102 EEKLVTLVQEKNDLQLQVQAESENLLDAEERCDQLIK-AKFQLEAKIKEVTERAEDEEEI 160
Query: 245 EEDLILNKNKLE----QANKDLEEKE-------KQLTATEAEVAALNRKVQQIEEDLEK- 388
+L K KLE + KD+++ E K+ ATE +V L ++ ++E + K
Sbjct: 161 NAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEELSGLDETIAKL 220
Query: 389 SEERSG--TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAE--- 553
+ E+ A Q+ L+ Q+ ++ +++ +Q E ++ Q K+ R+ E
Sbjct: 221 TREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNK 280
Query: 554 -DADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELK 679
+G + +E++ + ++R+K D + L+ +++
Sbjct: 281 RKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQLQSKVE 323
Score = 48.8 bits (111), Expect = 2e-05
Identities = 45/223 (20%), Positives = 105/223 (47%), Gaps = 8/223 (3%)
Frame = +2
Query: 86 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 265
+D + M+++ K N T E Q +A + E++ + EL + ++++ +
Sbjct: 456 IDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEA--- 512
Query: 266 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 445
+ ++ LEEKE ++ A ++ ++++ LE+ + A+ L A QS+
Sbjct: 513 ----GELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENK----AKNALAHALQSS 564
Query: 446 DENNRMCKVLENRAQQDEERMDQLTNQLKEARL-LAE-------DADGKSDEVSRKLAFV 601
+ C +L + ++++E +L L +A +A+ DA +++E+ +
Sbjct: 565 RHD---CDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAQEKL 621
Query: 602 EDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXKAN 730
L+ +E++V++ +AK + LE + + ++ L V +AN
Sbjct: 622 AQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERAN 664
Score = 47.6 bits (108), Expect = 5e-05
Identities = 33/134 (24%), Positives = 62/134 (46%), Gaps = 7/134 (5%)
Frame = +2
Query: 326 TEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEER 505
TE E+A + + Q+ +++L KSE + ++KL+ Q ++ + EER
Sbjct: 73 TEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEER 132
Query: 506 MDQLTN-------QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXL 664
DQL ++KE AED + + E++ K +EDE + + + ++ +
Sbjct: 133 CDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKV 192
Query: 665 EXELKVVGNSLKSL 706
E E N +K+L
Sbjct: 193 EKEKHATENKVKNL 206
Score = 46.4 bits (105), Expect = 1e-04
Identities = 51/226 (22%), Positives = 104/226 (46%), Gaps = 14/226 (6%)
Frame = +2
Query: 71 QKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEE 250
++A + I ++ A K + + D+ ++ D L KV +E + K+ + E
Sbjct: 152 ERAEDEEEINAELTAKKRKLE---DECSELKKDIDDLELTLAKVEKEKHATENKVKNLTE 208
Query: 251 DLI-LNKN--KLEQANKDLEEKEKQ----LTATEAEVAALNR---KVQQIEEDLEKSEER 400
+L L++ KL + K L+E +Q L A E +V +LN+ K++Q EDLE S E+
Sbjct: 209 ELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQ 268
Query: 401 SGTAQQKLLEAQQSADENNRMCKV----LENRAQQDEERMDQLTNQLKEARLLAEDADGK 568
+ L ++ + + ++ + LEN QQ +ER+ + + + + ED
Sbjct: 269 EKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTL 328
Query: 569 SDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSL 706
+ +K+ ++ +E E+ +++ A + E + L+ L
Sbjct: 329 GLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEEL 374
Score = 46.0 bits (104), Expect = 1e-04
Identities = 46/201 (22%), Positives = 95/201 (47%), Gaps = 22/201 (10%)
Frame = +2
Query: 161 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 340
EQ+ D + + + + EL+K Q+E + + LE+A LE +E ++ + E+
Sbjct: 734 EQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHEEAKILRIQLEL 793
Query: 341 ----AALNRKVQQIEEDLE---KSEERSGTAQQKLLEAQ-QSADENNRMCKVLE------ 478
+ ++RK+ + +E++E ++ +R+ Q L+A+ +S +E R+ K +E
Sbjct: 794 TQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKKKMEGDLNEI 853
Query: 479 -------NR-AQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRV 634
NR A + + + + QLK+ +L +DA +++ +LA VE + + V
Sbjct: 854 EIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALQTQEDLKEQLAIVERRANLLQAEV 913
Query: 635 KSGDAKISXLEXELKVVGNSL 697
+ A + E K+ L
Sbjct: 914 EELRATLEQTERARKLAEQEL 934
Score = 45.6 bits (103), Expect = 2e-04
Identities = 30/153 (19%), Positives = 74/153 (48%)
Frame = +2
Query: 164 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 343
QQA D +L+AE+ ++V L K +++E+ + ++ LEQ K + E+ E ++
Sbjct: 232 QQALD-DLQAEE--DKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLK 288
Query: 344 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 523
+ +E D ++ +ER + + Q ++ + + + ++ + R+++L
Sbjct: 289 LAQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEE 348
Query: 524 QLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 622
+++ R + + + +R+L + + LE A
Sbjct: 349 EIEAERATRAKTEKQRSDYARELEELSERLEEA 381
Score = 39.5 bits (88), Expect = 0.012
Identities = 36/185 (19%), Positives = 89/185 (48%), Gaps = 4/185 (2%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
+++A + A ++++A + + A A EQ+ D+N R + ++ + L ++E
Sbjct: 903 ERRANLLQAEVEELRATLEQTERARKLA---EQELLDSNERVQLLHTQNTSLIHTKKKLE 959
Query: 248 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 427
DL+ ++++E A++D E++ + A + ++++ ++ E +Q +
Sbjct: 960 TDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVK 1019
Query: 428 EAQQSADENNRMC-KVLENRAQQDEERMDQLTNQLK-EARLLAEDADG--KSDEVSRKLA 595
+ Q DE ++ K + + Q+ E R+ +L +L+ E + E G K + ++L
Sbjct: 1020 DLQHRLDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRKYERRVKELT 1079
Query: 596 FVEDE 610
+ +E
Sbjct: 1080 YQSEE 1084
Score = 34.7 bits (76), Expect = 0.35
Identities = 37/175 (21%), Positives = 84/175 (48%), Gaps = 3/175 (1%)
Frame = +2
Query: 161 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 340
+++ ++ R E++ EE+ + A+ E+ +LE+ ++ LEE +T+T+ E
Sbjct: 333 QKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERLEE-AGGVTSTQIE- 390
Query: 341 AALNRKVQQIEEDLEKSEERSGTAQQKLLEA---QQSADENNRMCKVLENRAQQDEERMD 511
LN+K + L + E + T Q + + A ++ AD + + ++N Q+ +++++
Sbjct: 391 --LNKKREAEFLKLRRDLEEA-TLQHEAMVATLRKKHADSVAELGEQIDN-LQRVKQKLE 446
Query: 512 QLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXEL 676
+ + E +L +D + VS+ A +E ED++ K ++ L
Sbjct: 447 K---EKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSL 498
>S78271-1|AAB34405.1| 1233|Homo sapiens SB1.8/DXS423E protein.
Length = 1233
Score = 58.4 bits (135), Expect = 2e-08
Identities = 42/165 (25%), Positives = 89/165 (53%), Gaps = 6/165 (3%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQ-QARDANLRAEKVNEEVR---ELQKKL 235
+++ MD ++K+M +++ + ++ + Q Q RD L +V + R E K+
Sbjct: 327 KKRKGDMDELEKEMLSVEKARQEFEERMEEESQSQGRDLTLEENQVKKYHRLKEEASKRA 386
Query: 236 AQVEEDLI-LNKN-KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGT 409
A + ++L N++ K +Q DLEE++K TEA++ R++++ ++ +EK EE T
Sbjct: 387 ATLAQELEKFNRDQKADQDRLDLEERKK--VETEAKIKQKLREIEENQKRIEKLEEYITT 444
Query: 410 AQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL 544
++Q L E ++ E ++ + R + + ++Q+ QL +AR+
Sbjct: 445 SKQSLEEQKKLEGELTEEVEMAKRRIDEINKELNQVMEQLGDARI 489
Score = 46.4 bits (105), Expect = 1e-04
Identities = 41/191 (21%), Positives = 87/191 (45%), Gaps = 18/191 (9%)
Frame = +2
Query: 161 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKL-------EQANKDLEEKEKQL 319
E + N N+E+ + +K++ +VE++L K +L +Q K+++EK+ +L
Sbjct: 232 EVEIEKLNKELASKNKEIEKDKKRMDKVEDELKEKKKELGKMMREQQQIEKEIKEKDSEL 291
Query: 320 TATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDE 499
+ + LE +++ AQ+ + + DE + +E Q+ E
Sbjct: 292 NQKRPQYIKAKENTSHKIKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLSVEKARQEFE 351
Query: 500 ERMDQ--------LT---NQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGD 646
ERM++ LT NQ+K+ L E+A ++ ++++L + + +DR+ +
Sbjct: 352 ERMEEESQSQGRDLTLEENQVKKYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEE 411
Query: 647 AKISXLEXELK 679
K E ++K
Sbjct: 412 RKKVETEAKIK 422
Score = 42.3 bits (95), Expect = 0.002
Identities = 32/171 (18%), Positives = 84/171 (49%), Gaps = 1/171 (0%)
Frame = +2
Query: 128 KDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEK 307
K N + +Q+ +A+ R +++ +EV Q +L + L N+ ++E+ NK+L K
Sbjct: 189 KKNIAAERKEAKQEKEEAD-RYQRLKDEVVRAQVQLQLFK--LYHNEVEIEKLNKELASK 245
Query: 308 EKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENN-RMCKVLENR 484
K++ + + + ++++ +++L K ++++ E ++ + K EN
Sbjct: 246 NKEIEKDKKRMDKVEDELKEKKKELGKMMREQQQIEKEIKEKDSELNQKRPQYIKAKENT 305
Query: 485 AQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVK 637
+ + ++++ L+ A+ + G DE+ +++ VE + E+R++
Sbjct: 306 SHK-IKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLSVEKARQEFEERME 355
Score = 40.3 bits (90), Expect = 0.007
Identities = 37/203 (18%), Positives = 95/203 (46%), Gaps = 13/203 (6%)
Frame = +2
Query: 98 KKKMQAMKLEKDNA--MDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN 271
+K+ Q +K +++ + + K + ++ ++A +K ++ EL+K++ VE+ +
Sbjct: 293 QKRPQYIKAKENTSHKIKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLSVEKARQEFEE 352
Query: 272 KLEQAN----KDLEEKEKQL-------TATEAEVAALNRKVQQIEEDLEKSEERSGTAQQ 418
++E+ + +DL +E Q+ A L +++++ D + ++R ++
Sbjct: 353 RMEEESQSQGRDLTLEENQVKKYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEER 412
Query: 419 KLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAF 598
K +E + + R + + R ++ EE + L+E + L + + + R++
Sbjct: 413 KKVETEAKIKQKLREIEENQKRIEKLEEYITTSKQSLEEQKKLEGELTEEVEMAKRRIDE 472
Query: 599 VEDELEVAEDRVKSGDAKISXLE 667
+ EL +++ GDA+I E
Sbjct: 473 INKELNQVMEQL--GDARIDRQE 493
Score = 34.7 bits (76), Expect = 0.35
Identities = 35/175 (20%), Positives = 84/175 (48%), Gaps = 4/175 (2%)
Frame = +2
Query: 188 RAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQ 367
R+ V +E + +K++ + EED N ++ + N E KE + EA+ + Q+
Sbjct: 160 RSGDVAQEYDKRKKEMVKAEEDTQFNYHR--KKNIAAERKEAKQEKEEAD------RYQR 211
Query: 368 IEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLL 547
+++++ +++ + KL + ++ N+ ++D++RMD++ ++LKE +
Sbjct: 212 LKDEVVRAQVQLQLF--KLYHNEVEIEKLNKELASKNKEIEKDKKRMDKVEDELKEKKKE 269
Query: 548 AEDADGKSDEVSRKLAFVEDELEVAEDR-VKSGD---AKISXLEXELKVVGNSLK 700
+ ++ +++ + EL + +K+ + KI LE K + N+ K
Sbjct: 270 LGKMMREQQQIEKEIKEKDSELNQKRPQYIKAKENTSHKIKKLEAAKKSLQNAQK 324
Score = 33.9 bits (74), Expect = 0.60
Identities = 44/224 (19%), Positives = 95/224 (42%), Gaps = 11/224 (4%)
Frame = +2
Query: 86 MDAIKKKMQAMKLEKDNAMDKADTCEQQAR--DANLRAE-----KVNEEVRELQKKLAQV 244
MD ++ +++ K E M + E++ + D+ L + K E KKL
Sbjct: 256 MDKVEDELKEKKKELGKMMREQQQIEKEIKEKDSELNQKRPQYIKAKENTSHKIKKLEAA 315
Query: 245 EEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL 424
++ L + ++ D++E EK++ + E + Q+ EE +E EE +
Sbjct: 316 KKSLQNAQKHYKKRKGDMDELEKEMLSVE-------KARQEFEERME--EESQSQGRDLT 366
Query: 425 LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVE 604
LE Q + +R+ + RA + +++ K + + + K E K+
Sbjct: 367 LEENQ-VKKYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEERKKVETEAKIKQKL 425
Query: 605 DELEVAEDRVKSGDAKIS----XLEXELKVVGNSLKSLEVSEXK 724
E+E + R++ + I+ LE + K+ G + +E+++ +
Sbjct: 426 REIEENQKRIEKLEEYITTSKQSLEEQKKLEGELTEEVEMAKRR 469
Score = 31.1 bits (67), Expect = 4.3
Identities = 37/199 (18%), Positives = 83/199 (41%), Gaps = 14/199 (7%)
Frame = +2
Query: 86 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKL-------AQV 244
++ +KK+ Q D M + + Q N E+ E++KKL +
Sbjct: 849 IEKLKKEEQRHMKIIDETMAQLQDLKNQHLAKKSEVNDKNHEMEEIRKKLGGANKEMTHL 908
Query: 245 EEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQI--EEDLEKSEER-SGTAQ 415
++++ + KLEQ D + + ++ + I EE + E+ SG+ +
Sbjct: 909 QKEVTAIETKLEQKRSDRHNLLQACKMQDIKLPLSKGTMDDISQEEGSSQGEDSVSGSQR 968
Query: 416 QKLLEAQQSADE--NNRMCKVLENRAQQDE--ERMDQLTNQLKEARLLAEDADGKSDEVS 583
+ A+++ E +C+ L++ ++E + M+ L +L E + + + + +
Sbjct: 969 ISSIYAREALIEIDYGDLCEDLKDAQAEEEIKQEMNTLQQKLNEQQSVLQRIAAPNMKAM 1028
Query: 584 RKLAFVEDELEVAEDRVKS 640
KL V D+ + D ++
Sbjct: 1029 EKLESVRDKFQETSDEFEA 1047
>D80000-1|BAA11495.2| 1233|Homo sapiens KIAA0178 protein.
Length = 1233
Score = 58.4 bits (135), Expect = 2e-08
Identities = 42/165 (25%), Positives = 89/165 (53%), Gaps = 6/165 (3%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQ-QARDANLRAEKVNEEVR---ELQKKL 235
+++ MD ++K+M +++ + ++ + Q Q RD L +V + R E K+
Sbjct: 327 KKRKGDMDELEKEMLSVEKARQEFEERMEEESQSQGRDLTLEENQVKKYHRLKEEASKRA 386
Query: 236 AQVEEDLI-LNKN-KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGT 409
A + ++L N++ K +Q DLEE++K TEA++ R++++ ++ +EK EE T
Sbjct: 387 ATLAQELEKFNRDQKADQDRLDLEERKK--VETEAKIKQKLREIEENQKRIEKLEEYITT 444
Query: 410 AQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL 544
++Q L E ++ E ++ + R + + ++Q+ QL +AR+
Sbjct: 445 SKQSLEEQKKLEGELTEEVEMAKRRIDEINKELNQVMEQLGDARI 489
Score = 46.4 bits (105), Expect = 1e-04
Identities = 41/191 (21%), Positives = 87/191 (45%), Gaps = 18/191 (9%)
Frame = +2
Query: 161 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKL-------EQANKDLEEKEKQL 319
E + N N+E+ + +K++ +VE++L K +L +Q K+++EK+ +L
Sbjct: 232 EVEIEKLNKELASKNKEIEKDKKRMDKVEDELKEKKKELGKMMREQQQIEKEIKEKDSEL 291
Query: 320 TATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDE 499
+ + LE +++ AQ+ + + DE + +E Q+ E
Sbjct: 292 NQKRPQYIKAKENTSHKIKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLSVEKARQEFE 351
Query: 500 ERMDQ--------LT---NQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGD 646
ERM++ LT NQ+K+ L E+A ++ ++++L + + +DR+ +
Sbjct: 352 ERMEEESQSQGRDLTLEENQVKKYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEE 411
Query: 647 AKISXLEXELK 679
K E ++K
Sbjct: 412 RKKVETEAKIK 422
Score = 42.3 bits (95), Expect = 0.002
Identities = 32/171 (18%), Positives = 84/171 (49%), Gaps = 1/171 (0%)
Frame = +2
Query: 128 KDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEK 307
K N + +Q+ +A+ R +++ +EV Q +L + L N+ ++E+ NK+L K
Sbjct: 189 KKNIAAERKEAKQEKEEAD-RYQRLKDEVVRAQVQLQLFK--LYHNEVEIEKLNKELASK 245
Query: 308 EKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENN-RMCKVLENR 484
K++ + + + ++++ +++L K ++++ E ++ + K EN
Sbjct: 246 NKEIEKDKKRMDKVEDELKEKKKELGKMMREQQQIEKEIKEKDSELNQKRPQYIKAKENT 305
Query: 485 AQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVK 637
+ + ++++ L+ A+ + G DE+ +++ VE + E+R++
Sbjct: 306 SHK-IKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLSVEKARQEFEERME 355
Score = 40.3 bits (90), Expect = 0.007
Identities = 37/203 (18%), Positives = 95/203 (46%), Gaps = 13/203 (6%)
Frame = +2
Query: 98 KKKMQAMKLEKDNA--MDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN 271
+K+ Q +K +++ + + K + ++ ++A +K ++ EL+K++ VE+ +
Sbjct: 293 QKRPQYIKAKENTSHKIKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLSVEKARQEFEE 352
Query: 272 KLEQAN----KDLEEKEKQL-------TATEAEVAALNRKVQQIEEDLEKSEERSGTAQQ 418
++E+ + +DL +E Q+ A L +++++ D + ++R ++
Sbjct: 353 RMEEESQSQGRDLTLEENQVKKYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEER 412
Query: 419 KLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAF 598
K +E + + R + + R ++ EE + L+E + L + + + R++
Sbjct: 413 KKVETEAKIKQKLREIEENQKRIEKLEEYITTSKQSLEEQKKLEGELTEEVEMAKRRIDE 472
Query: 599 VEDELEVAEDRVKSGDAKISXLE 667
+ EL +++ GDA+I E
Sbjct: 473 INKELNQVMEQL--GDARIDRQE 493
Score = 34.3 bits (75), Expect = 0.46
Identities = 34/175 (19%), Positives = 85/175 (48%), Gaps = 4/175 (2%)
Frame = +2
Query: 188 RAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQ 367
R+ ++ +E + +K++ + EED N ++ + N E KE + EA+ + Q+
Sbjct: 160 RSGELAQEYDKRKKEMVKAEEDTQFNYHR--KKNIAAERKEAKQEKEEAD------RYQR 211
Query: 368 IEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLL 547
+++++ +++ + KL + ++ N+ ++D++RMD++ ++LKE +
Sbjct: 212 LKDEVVRAQVQLQLF--KLYHNEVEIEKLNKELASKNKEIEKDKKRMDKVEDELKEKKKE 269
Query: 548 AEDADGKSDEVSRKLAFVEDELEVAEDR-VKSGD---AKISXLEXELKVVGNSLK 700
+ ++ +++ + EL + +K+ + KI LE K + N+ K
Sbjct: 270 LGKMMREQQQIEKEIKEKDSELNQKRPQYIKAKENTSHKIKKLEAAKKSLQNAQK 324
Score = 33.9 bits (74), Expect = 0.60
Identities = 44/224 (19%), Positives = 95/224 (42%), Gaps = 11/224 (4%)
Frame = +2
Query: 86 MDAIKKKMQAMKLEKDNAMDKADTCEQQAR--DANLRAE-----KVNEEVRELQKKLAQV 244
MD ++ +++ K E M + E++ + D+ L + K E KKL
Sbjct: 256 MDKVEDELKEKKKELGKMMREQQQIEKEIKEKDSELNQKRPQYIKAKENTSHKIKKLEAA 315
Query: 245 EEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL 424
++ L + ++ D++E EK++ + E + Q+ EE +E EE +
Sbjct: 316 KKSLQNAQKHYKKRKGDMDELEKEMLSVE-------KARQEFEERME--EESQSQGRDLT 366
Query: 425 LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVE 604
LE Q + +R+ + RA + +++ K + + + K E K+
Sbjct: 367 LEENQ-VKKYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEERKKVETEAKIKQKL 425
Query: 605 DELEVAEDRVKSGDAKIS----XLEXELKVVGNSLKSLEVSEXK 724
E+E + R++ + I+ LE + K+ G + +E+++ +
Sbjct: 426 REIEENQKRIEKLEEYITTSKQSLEEQKKLEGELTEEVEMAKRR 469
Score = 31.1 bits (67), Expect = 4.3
Identities = 37/199 (18%), Positives = 83/199 (41%), Gaps = 14/199 (7%)
Frame = +2
Query: 86 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKL-------AQV 244
++ +KK+ Q D M + + Q N E+ E++KKL +
Sbjct: 849 IEKLKKEEQRHMKIIDETMAQLQDLKNQHLAKKSEVNDKNHEMEEIRKKLGGANKEMTHL 908
Query: 245 EEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQI--EEDLEKSEER-SGTAQ 415
++++ + KLEQ D + + ++ + I EE + E+ SG+ +
Sbjct: 909 QKEVTAIETKLEQKRSDRHNLLQACKMQDIKLPLSKGTMDDISQEEGSSQGEDSVSGSQR 968
Query: 416 QKLLEAQQSADE--NNRMCKVLENRAQQDE--ERMDQLTNQLKEARLLAEDADGKSDEVS 583
+ A+++ E +C+ L++ ++E + M+ L +L E + + + + +
Sbjct: 969 ISSIYAREALIEIDYGDLCEDLKDAQAEEEIKQEMNTLQQKLNEQQSVLQRIAAPNMKAM 1028
Query: 584 RKLAFVEDELEVAEDRVKS 640
KL V D+ + D ++
Sbjct: 1029 EKLESVRDKFQETSDEFEA 1047
>BC127816-1|AAI27817.1| 416|Homo sapiens Unknown (protein for
IMAGE:40131779) protein.
Length = 416
Score = 58.4 bits (135), Expect = 2e-08
Identities = 37/197 (18%), Positives = 100/197 (50%), Gaps = 2/197 (1%)
Frame = +2
Query: 95 IKKKMQAMKLEKDNAMD-KADTCEQQARDANLRAEKVNEEVRELQKKL-AQVEEDLILNK 268
+K+K++ KL + +AD ++ + + + + EE EL +L Q EE + +
Sbjct: 205 LKRKLERAKLLLPQQLQAEADHLGKELQSVSAKLQAQVEE-NELWNRLNQQQEEKMWRQE 263
Query: 269 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSAD 448
K+++ + ++E+E+++ E ++ +Q+ EE + + EE+ Q+K+ ++
Sbjct: 264 EKIQEWEEKIQEQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKM-QEQEKMRRQEEKIR 322
Query: 449 ENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAED 628
E + + + ++ EE++ + +++E + ++ + K E K+ E++++ E+
Sbjct: 323 EQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEE 382
Query: 629 RVKSGDAKISXLEXELK 679
+++ + K+ E L+
Sbjct: 383 KMRRQEEKMWEQEVRLR 399
Score = 56.0 bits (129), Expect = 1e-07
Identities = 34/190 (17%), Positives = 93/190 (48%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
QQ A D + K++Q++ + +++ + + + + + E+++E ++K+ + E
Sbjct: 218 QQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQE 277
Query: 248 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 427
E + + K+ + + ++E+E+++ E ++ K+++ EE + + EE+ ++K+
Sbjct: 278 EKIREQEEKIREQEEMMQEQEEKMGEQEEKMQE-QEKMRRQEEKIREQEEKIREQKEKIR 336
Query: 428 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 607
E ++ E + E Q+ EE+M + ++ E ++ + K K+ E
Sbjct: 337 EQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEV 396
Query: 608 ELEVAEDRVK 637
L E++++
Sbjct: 397 RLRQQEEKMQ 406
Score = 51.6 bits (118), Expect = 3e-06
Identities = 27/154 (17%), Positives = 77/154 (50%)
Frame = +2
Query: 161 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 340
E++ ++ + ++ E++RE ++K+ + EE + + K+ + + ++E+EK + E ++
Sbjct: 263 EEKIQEWEEKIQEQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEK-MRRQEEKI 321
Query: 341 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 520
K+++ +E + + EE+ ++K+ E ++ E E + + EE+M +
Sbjct: 322 REQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQE 381
Query: 521 NQLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 622
+++ + + + + K+ ++ LE A
Sbjct: 382 EKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEAA 415
Score = 51.2 bits (117), Expect = 4e-06
Identities = 27/146 (18%), Positives = 75/146 (51%), Gaps = 1/146 (0%)
Frame = +2
Query: 143 DKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLT 322
+K E++ ++ + + E++RE ++ + + EE + + K+++ K + +E+++
Sbjct: 264 EKIQEWEEKIQEQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEK-MRRQEEKIR 322
Query: 323 ATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA-DENNRMCKVLENRAQQDE 499
E ++ K+++ EE + + EE+ ++ + E ++ ++ +MC+ E + Q+ E
Sbjct: 323 EQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQ-EEKMQEQE 381
Query: 500 ERMDQLTNQLKEARLLAEDADGKSDE 577
E+M + ++ E + + K E
Sbjct: 382 EKMRRQEEKMWEQEVRLRQQEEKMQE 407
Score = 49.6 bits (113), Expect = 1e-05
Identities = 28/150 (18%), Positives = 74/150 (49%)
Frame = +2
Query: 89 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 268
+ I+++ + ++ +++ ++ + ++Q + EK+ E Q+K+ + EE + +
Sbjct: 271 EKIQEQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQE-----QEKMRRQEEKIREQE 325
Query: 269 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSAD 448
K+ + + + E+E+++ E ++ +Q+ EE + + EE+ ++K+ E ++
Sbjct: 326 EKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMR 385
Query: 449 ENNRMCKVLENRAQQDEERMDQLTNQLKEA 538
E R +Q EE+M + L+ A
Sbjct: 386 RQEEKMWEQEVRLRQQEEKMQEHQEHLEAA 415
>BC112127-1|AAI12128.1| 1233|Homo sapiens SMC1 structural
maintenance of chromosomes 1-like 1 protein.
Length = 1233
Score = 58.4 bits (135), Expect = 2e-08
Identities = 42/165 (25%), Positives = 89/165 (53%), Gaps = 6/165 (3%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQ-QARDANLRAEKVNEEVR---ELQKKL 235
+++ MD ++K+M +++ + ++ + Q Q RD L +V + R E K+
Sbjct: 327 KKRKGDMDELEKEMLSVEKARQEFEERMEEESQSQGRDLTLEENQVKKYHRLKEEASKRA 386
Query: 236 AQVEEDLI-LNKN-KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGT 409
A + ++L N++ K +Q DLEE++K TEA++ R++++ ++ +EK EE T
Sbjct: 387 ATLAQELEKFNRDQKADQDRLDLEERKK--VETEAKIKQKLREIEENQKRIEKLEEYITT 444
Query: 410 AQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL 544
++Q L E ++ E ++ + R + + ++Q+ QL +AR+
Sbjct: 445 SKQSLEEQKKLEGELTEEVEMAKRRIDEINKELNQVMEQLGDARI 489
Score = 46.4 bits (105), Expect = 1e-04
Identities = 41/191 (21%), Positives = 87/191 (45%), Gaps = 18/191 (9%)
Frame = +2
Query: 161 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKL-------EQANKDLEEKEKQL 319
E + N N+E+ + +K++ +VE++L K +L +Q K+++EK+ +L
Sbjct: 232 EVEIEKLNKELASKNKEIEKDKKRMDKVEDELKEKKKELGKMMREQQQIEKEIKEKDSEL 291
Query: 320 TATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDE 499
+ + LE +++ AQ+ + + DE + +E Q+ E
Sbjct: 292 NQKRPQYIKAKENTSHKIKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLSVEKARQEFE 351
Query: 500 ERMDQ--------LT---NQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGD 646
ERM++ LT NQ+K+ L E+A ++ ++++L + + +DR+ +
Sbjct: 352 ERMEEESQSQGRDLTLEENQVKKYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEE 411
Query: 647 AKISXLEXELK 679
K E ++K
Sbjct: 412 RKKVETEAKIK 422
Score = 42.3 bits (95), Expect = 0.002
Identities = 32/171 (18%), Positives = 84/171 (49%), Gaps = 1/171 (0%)
Frame = +2
Query: 128 KDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEK 307
K N + +Q+ +A+ R +++ +EV Q +L + L N+ ++E+ NK+L K
Sbjct: 189 KKNIAAERKEAKQEKEEAD-RYQRLKDEVVRAQVQLQLFK--LYHNEVEIEKLNKELASK 245
Query: 308 EKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENN-RMCKVLENR 484
K++ + + + ++++ +++L K ++++ E ++ + K EN
Sbjct: 246 NKEIEKDKKRMDKVEDELKEKKKELGKMMREQQQIEKEIKEKDSELNQKRPQYIKAKENT 305
Query: 485 AQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVK 637
+ + ++++ L+ A+ + G DE+ +++ VE + E+R++
Sbjct: 306 SHK-IKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLSVEKARQEFEERME 355
Score = 40.3 bits (90), Expect = 0.007
Identities = 37/203 (18%), Positives = 95/203 (46%), Gaps = 13/203 (6%)
Frame = +2
Query: 98 KKKMQAMKLEKDNA--MDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN 271
+K+ Q +K +++ + + K + ++ ++A +K ++ EL+K++ VE+ +
Sbjct: 293 QKRPQYIKAKENTSHKIKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLSVEKARQEFEE 352
Query: 272 KLEQAN----KDLEEKEKQL-------TATEAEVAALNRKVQQIEEDLEKSEERSGTAQQ 418
++E+ + +DL +E Q+ A L +++++ D + ++R ++
Sbjct: 353 RMEEESQSQGRDLTLEENQVKKYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEER 412
Query: 419 KLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAF 598
K +E + + R + + R ++ EE + L+E + L + + + R++
Sbjct: 413 KKVETEAKIKQKLREIEENQKRIEKLEEYITTSKQSLEEQKKLEGELTEEVEMAKRRIDE 472
Query: 599 VEDELEVAEDRVKSGDAKISXLE 667
+ EL +++ GDA+I E
Sbjct: 473 INKELNQVMEQL--GDARIDRQE 493
Score = 34.3 bits (75), Expect = 0.46
Identities = 34/175 (19%), Positives = 85/175 (48%), Gaps = 4/175 (2%)
Frame = +2
Query: 188 RAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQ 367
R+ ++ +E + +K++ + EED N ++ + N E KE + EA+ + Q+
Sbjct: 160 RSGELAQEYDKRKKEMVKAEEDTQFNYHR--KKNIAAERKEAKQEKEEAD------RYQR 211
Query: 368 IEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLL 547
+++++ +++ + KL + ++ N+ ++D++RMD++ ++LKE +
Sbjct: 212 LKDEVVRAQVQLQLF--KLYHNEVEIEKLNKELASKNKEIEKDKKRMDKVEDELKEKKKE 269
Query: 548 AEDADGKSDEVSRKLAFVEDELEVAEDR-VKSGD---AKISXLEXELKVVGNSLK 700
+ ++ +++ + EL + +K+ + KI LE K + N+ K
Sbjct: 270 LGKMMREQQQIEKEIKEKDSELNQKRPQYIKAKENTSHKIKKLEAAKKSLQNAQK 324
Score = 33.9 bits (74), Expect = 0.60
Identities = 44/224 (19%), Positives = 95/224 (42%), Gaps = 11/224 (4%)
Frame = +2
Query: 86 MDAIKKKMQAMKLEKDNAMDKADTCEQQAR--DANLRAE-----KVNEEVRELQKKLAQV 244
MD ++ +++ K E M + E++ + D+ L + K E KKL
Sbjct: 256 MDKVEDELKEKKKELGKMMREQQQIEKEIKEKDSELNQKRPQYIKAKENTSHKIKKLEAA 315
Query: 245 EEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL 424
++ L + ++ D++E EK++ + E + Q+ EE +E EE +
Sbjct: 316 KKSLQNAQKHYKKRKGDMDELEKEMLSVE-------KARQEFEERME--EESQSQGRDLT 366
Query: 425 LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVE 604
LE Q + +R+ + RA + +++ K + + + K E K+
Sbjct: 367 LEENQ-VKKYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEERKKVETEAKIKQKL 425
Query: 605 DELEVAEDRVKSGDAKIS----XLEXELKVVGNSLKSLEVSEXK 724
E+E + R++ + I+ LE + K+ G + +E+++ +
Sbjct: 426 REIEENQKRIEKLEEYITTSKQSLEEQKKLEGELTEEVEMAKRR 469
Score = 31.1 bits (67), Expect = 4.3
Identities = 37/199 (18%), Positives = 83/199 (41%), Gaps = 14/199 (7%)
Frame = +2
Query: 86 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKL-------AQV 244
++ +KK+ Q D M + + Q N E+ E++KKL +
Sbjct: 849 IEKLKKEEQRHMKIIDETMAQLQDLKNQHLAKKSEVNDKNHEMEEIRKKLGGANKEMTHL 908
Query: 245 EEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQI--EEDLEKSEER-SGTAQ 415
++++ + KLEQ D + + ++ + I EE + E+ SG+ +
Sbjct: 909 QKEVTAIETKLEQKRSDRHNLLQACKMQDIKLPLSKGTMDDISQEEGSSQGEDSVSGSQR 968
Query: 416 QKLLEAQQSADE--NNRMCKVLENRAQQDE--ERMDQLTNQLKEARLLAEDADGKSDEVS 583
+ A+++ E +C+ L++ ++E + M+ L +L E + + + + +
Sbjct: 969 ISSIYAREALIEIDYGDLCEDLKDAQAEEEIKQEMNTLQQKLNEQQSVLQRIAAPNMKAM 1028
Query: 584 RKLAFVEDELEVAEDRVKS 640
KL V D+ + D ++
Sbjct: 1029 EKLESVRDKFQETSDEFEA 1047
>BC064368-1|AAH64368.1| 847|Homo sapiens SMC1A protein protein.
Length = 847
Score = 58.4 bits (135), Expect = 2e-08
Identities = 42/165 (25%), Positives = 89/165 (53%), Gaps = 6/165 (3%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQ-QARDANLRAEKVNEEVR---ELQKKL 235
+++ MD ++K+M +++ + ++ + Q Q RD L +V + R E K+
Sbjct: 327 KKRKGDMDELEKEMLSVEKARQEFEERMEEESQSQGRDLTLEENQVKKYHRLKEEASKRA 386
Query: 236 AQVEEDLI-LNKN-KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGT 409
A + ++L N++ K +Q DLEE++K TEA++ R++++ ++ +EK EE T
Sbjct: 387 ATLAQELEKFNRDQKADQDRLDLEERKK--VETEAKIKQKLREIEENQKRIEKLEEYITT 444
Query: 410 AQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL 544
++Q L E ++ E ++ + R + + ++Q+ QL +AR+
Sbjct: 445 SKQSLEEQKKLEGELTEEVEMAKRRIDEINKELNQVMEQLGDARI 489
Score = 46.4 bits (105), Expect = 1e-04
Identities = 41/191 (21%), Positives = 87/191 (45%), Gaps = 18/191 (9%)
Frame = +2
Query: 161 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKL-------EQANKDLEEKEKQL 319
E + N N+E+ + +K++ +VE++L K +L +Q K+++EK+ +L
Sbjct: 232 EVEIEKLNKELASKNKEIEKDKKRMDKVEDELKEKKKELGKMMREQQQIEKEIKEKDSEL 291
Query: 320 TATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDE 499
+ + LE +++ AQ+ + + DE + +E Q+ E
Sbjct: 292 NQKRPQYIKAKENTSHKIKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLSVEKARQEFE 351
Query: 500 ERMDQ--------LT---NQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGD 646
ERM++ LT NQ+K+ L E+A ++ ++++L + + +DR+ +
Sbjct: 352 ERMEEESQSQGRDLTLEENQVKKYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEE 411
Query: 647 AKISXLEXELK 679
K E ++K
Sbjct: 412 RKKVETEAKIK 422
Score = 42.3 bits (95), Expect = 0.002
Identities = 32/171 (18%), Positives = 84/171 (49%), Gaps = 1/171 (0%)
Frame = +2
Query: 128 KDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEK 307
K N + +Q+ +A+ R +++ +EV Q +L + L N+ ++E+ NK+L K
Sbjct: 189 KKNIAAERKEAKQEKEEAD-RYQRLKDEVVRAQVQLQLFK--LYHNEVEIEKLNKELASK 245
Query: 308 EKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENN-RMCKVLENR 484
K++ + + + ++++ +++L K ++++ E ++ + K EN
Sbjct: 246 NKEIEKDKKRMDKVEDELKEKKKELGKMMREQQQIEKEIKEKDSELNQKRPQYIKAKENT 305
Query: 485 AQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVK 637
+ + ++++ L+ A+ + G DE+ +++ VE + E+R++
Sbjct: 306 SHK-IKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLSVEKARQEFEERME 355
Score = 40.3 bits (90), Expect = 0.007
Identities = 37/203 (18%), Positives = 95/203 (46%), Gaps = 13/203 (6%)
Frame = +2
Query: 98 KKKMQAMKLEKDNA--MDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN 271
+K+ Q +K +++ + + K + ++ ++A +K ++ EL+K++ VE+ +
Sbjct: 293 QKRPQYIKAKENTSHKIKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLSVEKARQEFEE 352
Query: 272 KLEQAN----KDLEEKEKQL-------TATEAEVAALNRKVQQIEEDLEKSEERSGTAQQ 418
++E+ + +DL +E Q+ A L +++++ D + ++R ++
Sbjct: 353 RMEEESQSQGRDLTLEENQVKKYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEER 412
Query: 419 KLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAF 598
K +E + + R + + R ++ EE + L+E + L + + + R++
Sbjct: 413 KKVETEAKIKQKLREIEENQKRIEKLEEYITTSKQSLEEQKKLEGELTEEVEMAKRRIDE 472
Query: 599 VEDELEVAEDRVKSGDAKISXLE 667
+ EL +++ GDA+I E
Sbjct: 473 INKELNQVMEQL--GDARIDRQE 493
Score = 34.3 bits (75), Expect = 0.46
Identities = 34/175 (19%), Positives = 85/175 (48%), Gaps = 4/175 (2%)
Frame = +2
Query: 188 RAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQ 367
R+ ++ +E + +K++ + EED N ++ + N E KE + EA+ + Q+
Sbjct: 160 RSGELAQEYDKRKKEMVKAEEDTQFNYHR--KKNIAAERKEAKQEKEEAD------RYQR 211
Query: 368 IEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLL 547
+++++ +++ + KL + ++ N+ ++D++RMD++ ++LKE +
Sbjct: 212 LKDEVVRAQVQLQLF--KLYHNEVEIEKLNKELASKNKEIEKDKKRMDKVEDELKEKKKE 269
Query: 548 AEDADGKSDEVSRKLAFVEDELEVAEDR-VKSGD---AKISXLEXELKVVGNSLK 700
+ ++ +++ + EL + +K+ + KI LE K + N+ K
Sbjct: 270 LGKMMREQQQIEKEIKEKDSELNQKRPQYIKAKENTSHKIKKLEAAKKSLQNAQK 324
Score = 33.9 bits (74), Expect = 0.60
Identities = 44/224 (19%), Positives = 95/224 (42%), Gaps = 11/224 (4%)
Frame = +2
Query: 86 MDAIKKKMQAMKLEKDNAMDKADTCEQQAR--DANLRAE-----KVNEEVRELQKKLAQV 244
MD ++ +++ K E M + E++ + D+ L + K E KKL
Sbjct: 256 MDKVEDELKEKKKELGKMMREQQQIEKEIKEKDSELNQKRPQYIKAKENTSHKIKKLEAA 315
Query: 245 EEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL 424
++ L + ++ D++E EK++ + E + Q+ EE +E EE +
Sbjct: 316 KKSLQNAQKHYKKRKGDMDELEKEMLSVE-------KARQEFEERME--EESQSQGRDLT 366
Query: 425 LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVE 604
LE Q + +R+ + RA + +++ K + + + K E K+
Sbjct: 367 LEENQ-VKKYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEERKKVETEAKIKQKL 425
Query: 605 DELEVAEDRVKSGDAKIS----XLEXELKVVGNSLKSLEVSEXK 724
E+E + R++ + I+ LE + K+ G + +E+++ +
Sbjct: 426 REIEENQKRIEKLEEYITTSKQSLEEQKKLEGELTEEVEMAKRR 469
>AY517555-1|AAT44528.1| 941|Homo sapiens hypothetical
rhabdomyosarcoma antigen MU-RMS-40.3 protein.
Length = 941
Score = 58.4 bits (135), Expect = 2e-08
Identities = 47/217 (21%), Positives = 107/217 (49%), Gaps = 5/217 (2%)
Frame = +2
Query: 83 TMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 262
T ++ + ++ E ++A A E++A+ A A + EE+++ Q A +E +
Sbjct: 728 TKKKLETDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLER---M 784
Query: 263 NKNKLEQANKDL-----EEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 427
KN LEQ KDL E ++ L + ++ L +++++E +LE ++++ + + L
Sbjct: 785 KKN-LEQTVKDLQHRLDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLR 843
Query: 428 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 607
+ ++ E + + ++ +D+L ++K + AE+AD +++ K +
Sbjct: 844 KYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKVKSYKRQAEEADEQANAHLTKFRKAQH 903
Query: 608 ELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSE 718
ELE AE+R +++++ L + + +S + SE
Sbjct: 904 ELEEAEERADIAESQVNKLRAKTRDFTSSRMVVHESE 940
Score = 48.8 bits (111), Expect = 2e-05
Identities = 45/223 (20%), Positives = 105/223 (47%), Gaps = 8/223 (3%)
Frame = +2
Query: 86 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 265
+D + M+++ K N T E Q +A + E++ + EL + ++++ +
Sbjct: 230 IDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEA--- 286
Query: 266 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 445
+ ++ LEEKE ++ A ++ ++++ LE+ + A+ L A QS+
Sbjct: 287 ----GELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENK----AKNALAHALQSS 338
Query: 446 DENNRMCKVLENRAQQDEERMDQLTNQLKEARL-LAE-------DADGKSDEVSRKLAFV 601
+ C +L + ++++E +L L +A +A+ DA +++E+ +
Sbjct: 339 RHD---CDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKL 395
Query: 602 EDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXKAN 730
L+ +E++V++ +AK + LE + + ++ L V +AN
Sbjct: 396 AQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERAN 438
Score = 45.6 bits (103), Expect = 2e-04
Identities = 30/153 (19%), Positives = 74/153 (48%)
Frame = +2
Query: 164 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 343
QQA D +L+AE+ ++V L K +++E+ + ++ LEQ K + E+ E ++
Sbjct: 6 QQALD-DLQAEE--DKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLK 62
Query: 344 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 523
+ +E D ++ +ER + + Q ++ + + + ++ + R+++L
Sbjct: 63 LAQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEE 122
Query: 524 QLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 622
+++ R + + + +R+L + + LE A
Sbjct: 123 EIEAERATRAKTEKQRSDYARELEELSERLEEA 155
Score = 45.6 bits (103), Expect = 2e-04
Identities = 46/201 (22%), Positives = 95/201 (47%), Gaps = 22/201 (10%)
Frame = +2
Query: 161 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 340
EQ+ D + + + + EL+K Q+E + + LE+A LE +E ++ + E+
Sbjct: 508 EQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHEEAKILRIQLEL 567
Query: 341 ----AALNRKVQQIEEDLE---KSEERSGTAQQKLLEAQ-QSADENNRMCKVLE------ 478
+ ++RK+ + +E++E ++ +R+ Q L+A+ +S +E R+ K +E
Sbjct: 568 TQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKKKMEGDLNEI 627
Query: 479 -------NR-AQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRV 634
NR A + + + + QLK+ +L +DA +++ +LA VE + + V
Sbjct: 628 EIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEV 687
Query: 635 KSGDAKISXLEXELKVVGNSL 697
+ A + E K+ L
Sbjct: 688 EELRATLEQTERARKLAEQEL 708
Score = 39.5 bits (88), Expect = 0.012
Identities = 36/185 (19%), Positives = 89/185 (48%), Gaps = 4/185 (2%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
+++A + A ++++A + + A A EQ+ D+N R + ++ + L ++E
Sbjct: 677 ERRANLLQAEVEELRATLEQTERARKLA---EQELLDSNERVQLLHTQNTSLIHTKKKLE 733
Query: 248 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 427
DL+ ++++E A++D E++ + A + ++++ ++ E +Q +
Sbjct: 734 TDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVK 793
Query: 428 EAQQSADENNRMC-KVLENRAQQDEERMDQLTNQLK-EARLLAEDADG--KSDEVSRKLA 595
+ Q DE ++ K + + Q+ E R+ +L +L+ E + E G K + ++L
Sbjct: 794 DLQHRLDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRKYERRVKELT 853
Query: 596 FVEDE 610
+ +E
Sbjct: 854 YQSEE 858
Score = 36.3 bits (80), Expect = 0.11
Identities = 26/143 (18%), Positives = 63/143 (44%)
Frame = +2
Query: 278 EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENN 457
+QA DL+ +E ++ + + L ++V+ +E LE+ ++ ++ + +
Sbjct: 6 QQALDDLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQ 65
Query: 458 RMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVK 637
LEN QQ +ER+ + + + + ED + +K+ ++ +E E+ ++
Sbjct: 66 ESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIE 125
Query: 638 SGDAKISXLEXELKVVGNSLKSL 706
+ A + E + L+ L
Sbjct: 126 AERATRAKTEKQRSDYARELEEL 148
Score = 34.7 bits (76), Expect = 0.35
Identities = 37/175 (21%), Positives = 84/175 (48%), Gaps = 3/175 (1%)
Frame = +2
Query: 161 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 340
+++ ++ R E++ EE+ + A+ E+ +LE+ ++ LEE +T+T+ E
Sbjct: 107 QKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERLEE-AGGVTSTQIE- 164
Query: 341 AALNRKVQQIEEDLEKSEERSGTAQQKLLEA---QQSADENNRMCKVLENRAQQDEERMD 511
LN+K + L + E + T Q + + A ++ AD + + ++N Q+ +++++
Sbjct: 165 --LNKKREAEFLKLRRDLEEA-TLQHEAMVATLRKKHADSVAELGEQIDN-LQRVKQKLE 220
Query: 512 QLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXEL 676
+ + E +L +D + VS+ A +E ED++ K ++ L
Sbjct: 221 K---EKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSL 272
Score = 31.9 bits (69), Expect = 2.4
Identities = 44/207 (21%), Positives = 92/207 (44%), Gaps = 5/207 (2%)
Frame = +2
Query: 119 KLEKDNAMDKADT--CEQQAR--DANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQA 286
K + D + K D C+ Q++ D + ++++ELQ ++ ++EE++ + E+A
Sbjct: 75 KQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEI-----EAERA 129
Query: 287 NKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMC 466
+ EK++ A E +EE E+ EE G ++ ++ E ++
Sbjct: 130 TRAKTEKQRSDYARE------------LEELSERLEEAGGVTSTQIELNKKREAEFLKLR 177
Query: 467 KVLENRAQQDEERMDQLTNQLKEA-RLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSG 643
+ LE Q E + L + ++ L E D V +KL + E ++ D + S
Sbjct: 178 RDLEEATLQHEAMVATLRKKHADSVAELGEQID-NLQRVKQKLEKEKSEFKLEIDDLSSS 236
Query: 644 DAKISXLEXELKVVGNSLKSLEVSEXK 724
+S + L+ + +L+ ++SE +
Sbjct: 237 MESVSKSKANLEKICRTLED-QLSEAR 262
>AL161779-1|CAI42089.1| 1233|Homo sapiens structural maintenance of
chromosomes 1A protein.
Length = 1233
Score = 58.4 bits (135), Expect = 2e-08
Identities = 42/165 (25%), Positives = 89/165 (53%), Gaps = 6/165 (3%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQ-QARDANLRAEKVNEEVR---ELQKKL 235
+++ MD ++K+M +++ + ++ + Q Q RD L +V + R E K+
Sbjct: 327 KKRKGDMDELEKEMLSVEKARQEFEERMEEESQSQGRDLTLEENQVKKYHRLKEEASKRA 386
Query: 236 AQVEEDLI-LNKN-KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGT 409
A + ++L N++ K +Q DLEE++K TEA++ R++++ ++ +EK EE T
Sbjct: 387 ATLAQELEKFNRDQKADQDRLDLEERKK--VETEAKIKQKLREIEENQKRIEKLEEYITT 444
Query: 410 AQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL 544
++Q L E ++ E ++ + R + + ++Q+ QL +AR+
Sbjct: 445 SKQSLEEQKKLEGELTEEVEMAKRRIDEINKELNQVMEQLGDARI 489
Score = 46.4 bits (105), Expect = 1e-04
Identities = 41/191 (21%), Positives = 87/191 (45%), Gaps = 18/191 (9%)
Frame = +2
Query: 161 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKL-------EQANKDLEEKEKQL 319
E + N N+E+ + +K++ +VE++L K +L +Q K+++EK+ +L
Sbjct: 232 EVEIEKLNKELASKNKEIEKDKKRMDKVEDELKEKKKELGKMMREQQQIEKEIKEKDSEL 291
Query: 320 TATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDE 499
+ + LE +++ AQ+ + + DE + +E Q+ E
Sbjct: 292 NQKRPQYIKAKENTSHKIKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLSVEKARQEFE 351
Query: 500 ERMDQ--------LT---NQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGD 646
ERM++ LT NQ+K+ L E+A ++ ++++L + + +DR+ +
Sbjct: 352 ERMEEESQSQGRDLTLEENQVKKYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEE 411
Query: 647 AKISXLEXELK 679
K E ++K
Sbjct: 412 RKKVETEAKIK 422
Score = 42.3 bits (95), Expect = 0.002
Identities = 32/171 (18%), Positives = 84/171 (49%), Gaps = 1/171 (0%)
Frame = +2
Query: 128 KDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEK 307
K N + +Q+ +A+ R +++ +EV Q +L + L N+ ++E+ NK+L K
Sbjct: 189 KKNIAAERKEAKQEKEEAD-RYQRLKDEVVRAQVQLQLFK--LYHNEVEIEKLNKELASK 245
Query: 308 EKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENN-RMCKVLENR 484
K++ + + + ++++ +++L K ++++ E ++ + K EN
Sbjct: 246 NKEIEKDKKRMDKVEDELKEKKKELGKMMREQQQIEKEIKEKDSELNQKRPQYIKAKENT 305
Query: 485 AQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVK 637
+ + ++++ L+ A+ + G DE+ +++ VE + E+R++
Sbjct: 306 SHK-IKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLSVEKARQEFEERME 355
Score = 40.3 bits (90), Expect = 0.007
Identities = 37/203 (18%), Positives = 95/203 (46%), Gaps = 13/203 (6%)
Frame = +2
Query: 98 KKKMQAMKLEKDNA--MDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN 271
+K+ Q +K +++ + + K + ++ ++A +K ++ EL+K++ VE+ +
Sbjct: 293 QKRPQYIKAKENTSHKIKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLSVEKARQEFEE 352
Query: 272 KLEQAN----KDLEEKEKQL-------TATEAEVAALNRKVQQIEEDLEKSEERSGTAQQ 418
++E+ + +DL +E Q+ A L +++++ D + ++R ++
Sbjct: 353 RMEEESQSQGRDLTLEENQVKKYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEER 412
Query: 419 KLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAF 598
K +E + + R + + R ++ EE + L+E + L + + + R++
Sbjct: 413 KKVETEAKIKQKLREIEENQKRIEKLEEYITTSKQSLEEQKKLEGELTEEVEMAKRRIDE 472
Query: 599 VEDELEVAEDRVKSGDAKISXLE 667
+ EL +++ GDA+I E
Sbjct: 473 INKELNQVMEQL--GDARIDRQE 493
Score = 34.3 bits (75), Expect = 0.46
Identities = 34/175 (19%), Positives = 85/175 (48%), Gaps = 4/175 (2%)
Frame = +2
Query: 188 RAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQ 367
R+ ++ +E + +K++ + EED N ++ + N E KE + EA+ + Q+
Sbjct: 160 RSGELAQEYDKRKKEMVKAEEDTQFNYHR--KKNIAAERKEAKQEKEEAD------RYQR 211
Query: 368 IEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLL 547
+++++ +++ + KL + ++ N+ ++D++RMD++ ++LKE +
Sbjct: 212 LKDEVVRAQVQLQLF--KLYHNEVEIEKLNKELASKNKEIEKDKKRMDKVEDELKEKKKE 269
Query: 548 AEDADGKSDEVSRKLAFVEDELEVAEDR-VKSGD---AKISXLEXELKVVGNSLK 700
+ ++ +++ + EL + +K+ + KI LE K + N+ K
Sbjct: 270 LGKMMREQQQIEKEIKEKDSELNQKRPQYIKAKENTSHKIKKLEAAKKSLQNAQK 324
Score = 33.9 bits (74), Expect = 0.60
Identities = 44/224 (19%), Positives = 95/224 (42%), Gaps = 11/224 (4%)
Frame = +2
Query: 86 MDAIKKKMQAMKLEKDNAMDKADTCEQQAR--DANLRAE-----KVNEEVRELQKKLAQV 244
MD ++ +++ K E M + E++ + D+ L + K E KKL
Sbjct: 256 MDKVEDELKEKKKELGKMMREQQQIEKEIKEKDSELNQKRPQYIKAKENTSHKIKKLEAA 315
Query: 245 EEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL 424
++ L + ++ D++E EK++ + E + Q+ EE +E EE +
Sbjct: 316 KKSLQNAQKHYKKRKGDMDELEKEMLSVE-------KARQEFEERME--EESQSQGRDLT 366
Query: 425 LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVE 604
LE Q + +R+ + RA + +++ K + + + K E K+
Sbjct: 367 LEENQ-VKKYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEERKKVETEAKIKQKL 425
Query: 605 DELEVAEDRVKSGDAKIS----XLEXELKVVGNSLKSLEVSEXK 724
E+E + R++ + I+ LE + K+ G + +E+++ +
Sbjct: 426 REIEENQKRIEKLEEYITTSKQSLEEQKKLEGELTEEVEMAKRR 469
Score = 31.1 bits (67), Expect = 4.3
Identities = 37/199 (18%), Positives = 83/199 (41%), Gaps = 14/199 (7%)
Frame = +2
Query: 86 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKL-------AQV 244
++ +KK+ Q D M + + Q N E+ E++KKL +
Sbjct: 849 IEKLKKEEQRHMKIIDETMAQLQDLKNQHLAKKSEVNDKNHEMEEIRKKLGGANKEMTHL 908
Query: 245 EEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQI--EEDLEKSEER-SGTAQ 415
++++ + KLEQ D + + ++ + I EE + E+ SG+ +
Sbjct: 909 QKEVTAIETKLEQKRSDRHNLLQACKMQDIKLPLSKGTMDDISQEEGSSQGEDSVSGSQR 968
Query: 416 QKLLEAQQSADE--NNRMCKVLENRAQQDE--ERMDQLTNQLKEARLLAEDADGKSDEVS 583
+ A+++ E +C+ L++ ++E + M+ L +L E + + + + +
Sbjct: 969 ISSIYAREALIEIDYGDLCEDLKDAQAEEEIKQEMNTLQQKLNEQQSVLQRIAAPNMKAM 1028
Query: 584 RKLAFVEDELEVAEDRVKS 640
KL V D+ + D ++
Sbjct: 1029 EKLESVRDKFQETSDEFEA 1047
>AK097517-1|BAC05084.1| 621|Homo sapiens protein ( Homo sapiens cDNA
FLJ40198 fis, clone TESTI2019975, weakly similar to
TRICHOHYALIN. ).
Length = 621
Score = 58.4 bits (135), Expect = 2e-08
Identities = 35/211 (16%), Positives = 104/211 (49%), Gaps = 7/211 (3%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKL--EKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQ 241
Q++ + K++ Q K+ +++ ++ + +Q + + EK++E+ + +++ Q
Sbjct: 394 QEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQ 453
Query: 242 VEEDLILNKNKLEQANKDLEEKEK-----QLTATEAEVAALNRKVQQIEEDLEKSEERSG 406
+E++ + K+ + + +KEK ++ E +V K+ EE + + EE+
Sbjct: 454 EQEEMWRQEEKIREQEEIWRQKEKMHEQEKIWKQEEKVWRQEEKMHDQEEKIREQEEKMW 513
Query: 407 TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSR 586
++K+ E ++ E + + + ++ EE++ + +++E + ++ + K E
Sbjct: 514 RQEEKIREQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEE 573
Query: 587 KLAFVEDELEVAEDRVKSGDAKISXLEXELK 679
K+ E++++ E++++ + K+ E L+
Sbjct: 574 KMCEQEEKMQEQEEKMRRQEEKMWEQEVRLR 604
Score = 51.2 bits (117), Expect = 4e-06
Identities = 38/195 (19%), Positives = 98/195 (50%), Gaps = 7/195 (3%)
Frame = +2
Query: 62 P*QQKAATMDAIKKKMQAMKLEKDNAMDKADTC----EQQARDANLRAEKVNE---EVRE 220
P QQ A D + K++Q++ + +++ + +QQ + EK+ E +++E
Sbjct: 253 PQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQE 312
Query: 221 LQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEER 400
++K+ + EE + + K+ + + + EKE+++ E + K++++EE + + EE+
Sbjct: 313 QEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEK 372
Query: 401 SGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEV 580
++K+ E ++ ++ + + E + ++ E+R +Q ++ + E + K E
Sbjct: 373 IRELEEKMHEQEKIREQEEK--RQEEEKIREQEKRQEQEAKMWRQEEKIREQEE-KIREQ 429
Query: 581 SRKLAFVEDELEVAE 625
+K+ E+++ E
Sbjct: 430 EKKMWRQEEKIHEQE 444
Score = 48.8 bits (111), Expect = 2e-05
Identities = 30/167 (17%), Positives = 82/167 (49%), Gaps = 2/167 (1%)
Frame = +2
Query: 185 LRAEKVNEEVREL--QKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRK 358
+R E+ +E E+ Q++ + +E++ K K+ + K +++EK + E ++ K
Sbjct: 446 IREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIWKQEEK-VWRQEEKMHDQEEK 504
Query: 359 VQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEA 538
+++ EE + + EE+ ++K+ E ++ E + E + + EE++ + ++E
Sbjct: 505 IREQEEKMWRQEEKIREQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQ 564
Query: 539 RLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELK 679
+ + K E K+ E+++ E+++ + ++ E +++
Sbjct: 565 EEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQ 611
Score = 48.8 bits (111), Expect = 2e-05
Identities = 30/160 (18%), Positives = 77/160 (48%), Gaps = 3/160 (1%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVREL---QKKLA 238
++K + I ++ + M E++ + + +Q + + EK+ E+ ++ ++K+
Sbjct: 462 EEKIREQEEIWRQKEKMH-EQEKIWKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIR 520
Query: 239 QVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQ 418
+ EE + + K+ + + + E+E+++ E ++ +Q+ EE + + EE+ ++
Sbjct: 521 EQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEE 580
Query: 419 KLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEA 538
K+ E ++ E R +Q EE+M + L+ A
Sbjct: 581 KMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEAA 620
Score = 47.6 bits (108), Expect = 5e-05
Identities = 26/128 (20%), Positives = 65/128 (50%), Gaps = 1/128 (0%)
Frame = +2
Query: 197 KVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEE 376
K E+V ++K+ EE + + K+ + + + E+E+++ E ++ K+++ EE
Sbjct: 486 KQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQKEKIREQEE 545
Query: 377 DLEKSEERSGTAQQKLLEAQQSA-DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAE 553
+ + EE+ ++ + E ++ ++ +MC+ E + Q+ EE+M + ++ E +
Sbjct: 546 KIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQ-EEKMQEQEEKMRRQEEKMWEQEVRLR 604
Query: 554 DADGKSDE 577
+ K E
Sbjct: 605 QQEEKMQE 612
Score = 47.2 bits (107), Expect = 6e-05
Identities = 32/188 (17%), Positives = 87/188 (46%), Gaps = 5/188 (2%)
Frame = +2
Query: 89 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVREL-----QKKLAQVEED 253
+ I+++ + M +++ ++ E++ R + E++RE QK+ +E
Sbjct: 424 EKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEK 483
Query: 254 LILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEA 433
+ + K+ + + + ++E+++ E ++ K+++ EE + + EE+ ++K+ E
Sbjct: 484 IWKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQKEKIREQ 543
Query: 434 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDEL 613
++ E + E Q+ EE+M + ++ E ++ + K K+ E L
Sbjct: 544 EEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRL 603
Query: 614 EVAEDRVK 637
E++++
Sbjct: 604 RQQEEKMQ 611
Score = 46.4 bits (105), Expect = 1e-04
Identities = 40/196 (20%), Positives = 89/196 (45%), Gaps = 1/196 (0%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKL-AQV 244
Q+K +++ K ++Q E +++A Q + A+ + +E++ + KL AQV
Sbjct: 221 QEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQ-QQLQAEADHLGKELQSVSAKLQAQV 279
Query: 245 EEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL 424
EE+ + N+ +Q K ++EK + K+Q+ EE + + EE+ ++K+
Sbjct: 280 EENELWNRLNQQQEEKMWRQEEK--------IQEWEEKIQEQEEKIREQEEKIREQEEKM 331
Query: 425 LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVE 604
++ E + E + EE+M +L + E + + K E K+ +
Sbjct: 332 RRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHE-QEKIR-EQ 389
Query: 605 DELEVAEDRVKSGDAK 652
+E E++++ + +
Sbjct: 390 EEKRQEEEKIREQEKR 405
Score = 43.2 bits (97), Expect = 0.001
Identities = 41/221 (18%), Positives = 104/221 (47%), Gaps = 7/221 (3%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKV----NEEVRELQKKL 235
++K + ++ + M EK+ M + + + + R E++ E++REL++K+
Sbjct: 321 EEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKM 380
Query: 236 AQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQ 415
E++ I + + Q + + E+EK+ EA++ K+++ EE + + E++ +
Sbjct: 381 H--EQEKIREQEEKRQEEEKIREQEKR-QEQEAKMWRQEEKIREQEEKIREQEKKMWRQE 437
Query: 416 QKLLEAQQSADENNRMCKVLENRAQQDEE-RMDQLTNQLKEARLLAE--DADGKSDEVSR 586
+K+ E ++ +E E R +Q+E R ++ + +E E K +
Sbjct: 438 EKIHEQEKIREE--------EKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIWKQEE 489
Query: 587 KLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLE 709
K+ E+++ E++++ + K+ E +++ ++ E
Sbjct: 490 KVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQE 530
Score = 43.2 bits (97), Expect = 0.001
Identities = 22/139 (15%), Positives = 67/139 (48%)
Frame = +2
Query: 206 EEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLE 385
E++ + ++K+ + EE + + K+ + + + +E+++ E ++ K+++ +E +
Sbjct: 482 EKIWKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQKEKIR 541
Query: 386 KSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADG 565
+ EE+ ++K+ E ++ E E + + EE+M + +++ + +
Sbjct: 542 EQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEV 601
Query: 566 KSDEVSRKLAFVEDELEVA 622
+ + K+ ++ LE A
Sbjct: 602 RLRQQEEKMQEHQEHLEAA 620
Score = 37.5 bits (83), Expect = 0.049
Identities = 41/202 (20%), Positives = 97/202 (48%), Gaps = 1/202 (0%)
Frame = +2
Query: 77 AATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDL 256
A ++ + K + D +++ T E+ A L + +E EL++K A+++E L
Sbjct: 168 AGELEQALSAVATQKKKADRYIEEL-TKERDALSLELYRNTITDE--ELKEKNAKLQEKL 224
Query: 257 ILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQ 436
L +++ + +++E +++L E L ++ Q E D E +S +A+ L+AQ
Sbjct: 225 QLVESEKSEIQLNVKELKRKL---ERAKLLLPQQQLQAEADHLGKELQSVSAK---LQAQ 278
Query: 437 QSADEN-NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDEL 613
+E NR+ + E + + EE++ + +++E + + K E K+ E+ +
Sbjct: 279 VEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMM 338
Query: 614 EVAEDRVKSGDAKISXLEXELK 679
E++++ + + E +++
Sbjct: 339 WEKEEKMRRQEEMMWEKEEKMR 360
>BC129821-1|AAI29822.1| 315|Homo sapiens FLJ36144 protein protein.
Length = 315
Score = 58.0 bits (134), Expect = 3e-08
Identities = 39/174 (22%), Positives = 92/174 (52%), Gaps = 1/174 (0%)
Frame = +2
Query: 161 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 340
E++ R+ + + E++ +K+L + E++L + +L + K+L E+E+Q+ E ++
Sbjct: 26 EERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELRE-QKELREQEEQMQEQEEKM 84
Query: 341 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS-ADENNRMCKVLENRAQQDEERMDQL 517
K+++ EE + + EER ++++ E +Q D+ RM + + R ++ EERM +
Sbjct: 85 WEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWE-QDERLREKEERMREQ 143
Query: 518 TNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELK 679
++ + E+ K E +K E++++ E+R++ + K+ E ++
Sbjct: 144 EKMWEQVEKMREEK--KMQEQEKKTRDQEEKMQ-EEERIREREKKMREEEETMR 194
Score = 47.6 bits (108), Expect = 5e-05
Identities = 39/182 (21%), Positives = 86/182 (47%), Gaps = 4/182 (2%)
Frame = +2
Query: 98 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKV----NEEVRELQKKLAQVEEDLILN 265
K + Q K+ + + E + ++ LR +K E+++E ++K+ + EE +
Sbjct: 35 KMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQ 94
Query: 266 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 445
+ K+ + + L E+EKQ+ E ++ ++ + +E L + EER Q+K+ E +
Sbjct: 95 EEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERM-REQEKMWEQVEKM 153
Query: 446 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 625
E +M + E + + EE+M Q +++E + + E K+ E+ + E
Sbjct: 154 REEKKM-QEQEKKTRDQEEKM-QEEERIREREKKMREEEETMREQEEKMQKQEENMWEQE 211
Query: 626 DR 631
++
Sbjct: 212 EK 213
Score = 46.8 bits (106), Expect = 8e-05
Identities = 40/179 (22%), Positives = 91/179 (50%), Gaps = 1/179 (0%)
Frame = +2
Query: 95 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVREL-QKKLAQVEEDLILNKN 271
++++ Q M+ +++ M + D ++ + EK+ E+V ++ ++K Q +E ++
Sbjct: 112 MREQEQKMR-DQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQE 170
Query: 272 KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADE 451
+ Q + + E+EK++ E + K+Q+ EE++ + EE+ QQ+L E ++ E
Sbjct: 171 EKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKE-WQQQRLPEQKEKLWE 229
Query: 452 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAED 628
+M + E +Q+E+ DQ +E ++ ++ + ++V A +D E ED
Sbjct: 230 QEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDVG---AGGDDAREGGED 285
Score = 34.3 bits (75), Expect = 0.46
Identities = 20/130 (15%), Positives = 61/130 (46%)
Frame = +2
Query: 290 KDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCK 469
++L E+EK++ E ++ ++++ E + + EE+ +++L E ++ E + +
Sbjct: 6 EELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELR 65
Query: 470 VLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDA 649
+ +Q+E+ +Q ++ + E + K +L E ++ E +++ +
Sbjct: 66 EQKELREQEEQMQEQEEKMWEQEEKMREQEE-KMWRQEERLWEQEKQMREQEQKMRDQEE 124
Query: 650 KISXLEXELK 679
++ + L+
Sbjct: 125 RMWEQDERLR 134
>AF111782-1|AAD29948.1| 1938|Homo sapiens myosin heavy chain protein.
Length = 1938
Score = 58.0 bits (134), Expect = 3e-08
Identities = 51/212 (24%), Positives = 100/212 (47%), Gaps = 14/212 (6%)
Frame = +2
Query: 125 EKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL---NKNKLEQANKD 295
+K N DK + ++ D L KV +E + K+ + E++ N +KL + K
Sbjct: 943 KKRNLEDKCSSLKRDIDDLELTLTKVEKEKHATENKVKNLSEEMTALEENISKLTKEKKS 1002
Query: 296 LEEKEKQ----LTATEAEVAAL---NRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 454
L+E +Q L E +V L N K++Q +DLE S E+ + L A++ + +
Sbjct: 1003 LQEAHQQTLDDLQVEEDKVNGLIKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGD 1062
Query: 455 NRMCKV----LENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 622
+M + LEN QQ EE++ + +L + + +D S + +K+ ++ +E
Sbjct: 1063 LKMSQESIMDLENEKQQIEEKLKKKEFELSQLQARIDDEQVHSLQFQKKIKELQARIEEL 1122
Query: 623 EDRVKSGDAKISXLEXELKVVGNSLKSLEVSE 718
E+ +++ + +E + + L+ E+SE
Sbjct: 1123 EEEIEAEHTLRAKIEKQRSDLARELE--EISE 1152
Score = 52.0 bits (119), Expect = 2e-06
Identities = 54/223 (24%), Positives = 110/223 (49%), Gaps = 20/223 (8%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQA-MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQV 244
++K ++ K +Q ++ E +N MD + CE + L KV E L+++ ++
Sbjct: 878 EEKMVSLLQEKNDLQLQVQSETENLMDAEERCEGLIKSKILLEAKVKELTERLEEE-EEM 936
Query: 245 EEDLILNKNKLEQA----NKDLEEKEKQLT-------ATEAEVAALNRKVQQIEEDLEK- 388
+L+ K LE +D+++ E LT ATE +V L+ ++ +EE++ K
Sbjct: 937 NSELVAKKRNLEDKCSSLKRDIDDLELTLTKVEKEKHATENKVKNLSEEMTALEENISKL 996
Query: 389 -SEERS--GTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDA 559
E++S QQ L + Q D+ N + K+ QQ ++ ++ Q K+ R E A
Sbjct: 997 TKEKKSLQEAHQQTLDDLQVEEDKVNGLIKINAKLEQQTDD-LEGSLEQEKKLRADLERA 1055
Query: 560 DGKSD---EVSRK-LAFVEDELEVAEDRVKSGDAKISXLEXEL 676
K + ++S++ + +E+E + E+++K + ++S L+ +
Sbjct: 1056 KRKLEGDLKMSQESIMDLENEKQQIEEKLKKKEFELSQLQARI 1098
Score = 51.6 bits (118), Expect = 3e-06
Identities = 58/222 (26%), Positives = 105/222 (47%), Gaps = 8/222 (3%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRA-EKVNEEVRELQKKLAQV 244
+++ +A+ +Q+ + + D ++ + EQ+A+ RA K N EV + + K
Sbjct: 1324 EEETKAKNAMAHALQSSRHDCDLLREQYEE-EQEAKAELQRALSKANSEVAQWKTKY--- 1379
Query: 245 EEDLILNKNKLEQANKDL----EEKEKQLTATEAEVAALNRKVQQIE---EDLEKSEERS 403
E D I +LE+A K L +E E++ ++ A+L + Q+++ EDL + ERS
Sbjct: 1380 ETDAIQRTEELEEAKKKLAQRLQEAEEKTETANSKCASLEKTKQRLQGEVEDLMRDLERS 1439
Query: 404 GTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVS 583
TA L + Q++ D KVL Q+ +E +L KE+R L+ + ++
Sbjct: 1440 HTACATLDKKQRNFD------KVLAEWKQKLDESQAELEAAQKESRSLSTEL----FKMR 1489
Query: 584 RKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLE 709
V D+LE K+ +IS L ++ G +L+ E
Sbjct: 1490 NAYEEVVDQLETLRRENKNLQEEISDLTEQIAETGKNLQEAE 1531
Score = 47.2 bits (107), Expect = 6e-05
Identities = 34/179 (18%), Positives = 82/179 (45%)
Frame = +2
Query: 86 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 265
M A+++ + + EK + + +Q D + +KVN ++ + KL Q +DL
Sbjct: 986 MTALEENISKLTKEKKSLQEAH---QQTLDDLQVEEDKVNGLIK-INAKLEQQTDDL--- 1038
Query: 266 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 445
+ LEQ K + E+ E ++ + +E + ++ EE+ + +L + Q
Sbjct: 1039 EGSLEQEKKLRADLERAKRKLEGDLKMSQESIMDLENEKQQIEEKLKKKEFELSQLQARI 1098
Query: 446 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 622
D+ + + ++ + R+++L +++ L + + +++R+L + + LE A
Sbjct: 1099 DDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIEKQRSDLARELEEISERLEEA 1157
Score = 44.8 bits (101), Expect = 3e-04
Identities = 43/200 (21%), Positives = 100/200 (50%), Gaps = 29/200 (14%)
Frame = +2
Query: 92 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN 271
++ ++ M+ + +D+ +T ++ ++ + E++ E K L + E+ L +
Sbjct: 1480 SLSTELFKMRNAYEEVVDQLETLRRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQ 1539
Query: 272 K-------LEQANKDLEEKEKQLTATEAEVAA----LNRKVQQIEEDLE---KSEERSGT 409
+ LE+ LE +E ++ + E++ L+RKV + +E++E ++ +R+
Sbjct: 1540 EKSDLQVALEEVEGSLEHEESKILRVQLELSQVKSELDRKVIEKDEEIEQLKRNSQRAAE 1599
Query: 410 AQQKLLEAQ-QSADENNRMCKVLE-------------NRAQQDEER-MDQLTNQLKEARL 544
A Q +L+A+ +S ++ R+ K +E NR + +R + + QLK+++L
Sbjct: 1600 ALQSVLDAEIRSRNDALRLKKKMEGDLNEMEIQLGHSNRQMAETQRHLRTVQGQLKDSQL 1659
Query: 545 LAEDADGKSDEVSRKLAFVE 604
+DA ++++ +LA VE
Sbjct: 1660 HLDDALRSNEDLKEQLAIVE 1679
Score = 34.3 bits (75), Expect = 0.46
Identities = 34/184 (18%), Positives = 74/184 (40%), Gaps = 4/184 (2%)
Frame = +2
Query: 71 QKAATMDAIKKK---MQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQ 241
+K + +KKK + ++ D+ + +++ ++ R E++ EE+ A+
Sbjct: 1076 EKQQIEEKLKKKEFELSQLQARIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAK 1135
Query: 242 VEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSE-ERSGTAQQ 418
+E+ +LE+ ++ LEE +A + Q++ DLE++ + TA
Sbjct: 1136 IEKQRSDLARELEEISERLEEASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAAT 1195
Query: 419 KLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAF 598
+ S E L+ Q+ E+ +L ++ + E + R
Sbjct: 1196 LRKKQADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRT 1255
Query: 599 VEDE 610
VED+
Sbjct: 1256 VEDQ 1259
>U30872-1|AAA82935.1| 3113|Homo sapiens mitosin protein.
Length = 3113
Score = 57.6 bits (133), Expect = 4e-08
Identities = 46/222 (20%), Positives = 101/222 (45%), Gaps = 14/222 (6%)
Frame = +2
Query: 89 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVREL-------QKKLAQVE 247
+ +K+K Q ++ + + E + ++ + ++ +V EL Q+KL +E
Sbjct: 1981 EKMKEKTQELESHQSECLHCIQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLE 2040
Query: 248 ED---LILNK----NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSG 406
+D L L K N++ Q NK+ E K+ + +A ++ + + + + LE + G
Sbjct: 2041 KDSQALSLTKCELENQIAQLNKEKELLVKESESLQARLSESDYEKLNVSKALEAALVEKG 2100
Query: 407 TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSR 586
+L Q+ + R + L R + DE++ + +LKE + K + + R
Sbjct: 2101 EFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLER 2160
Query: 587 KLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEV 712
+L E+ E+ ++ A++ L+ +++ + SLK E+
Sbjct: 2161 ELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFEL 2202
Score = 52.0 bits (119), Expect = 2e-06
Identities = 47/236 (19%), Positives = 111/236 (47%), Gaps = 28/236 (11%)
Frame = +2
Query: 89 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 268
D++K K++ ++ E + + + A ++ E + ++ E+ + L E DL+ +
Sbjct: 2149 DSLKDKVENLERELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLR 2208
Query: 269 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTA------------ 412
++ E K ++EK+ QL+ + +++ +++ E+ + +E S TA
Sbjct: 2209 SEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELN 2268
Query: 413 --------QQKLLEA-QQSAD----ENNRMCKVLEN---RAQQDEERMDQLTNQLKEARL 544
Q++++A +QS D E +++ +E R + DE++ + QLKE+
Sbjct: 2269 EAVAALCGDQEIMKATEQSLDPPIEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESEH 2328
Query: 545 LAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEV 712
A+ G+ + + R+L E A ++ ++ L+ +++ + SL+ LE+
Sbjct: 2329 HADLLKGRVENLERELEIARTNQEHAALEAENSKGEVETLKAKIEGMTQSLRGLEL 2384
Score = 48.4 bits (110), Expect = 3e-05
Identities = 40/200 (20%), Positives = 90/200 (45%), Gaps = 1/200 (0%)
Frame = +2
Query: 101 KKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLE 280
+K + +EK+ ++K C + + ++ + + L++KL ++ EDL + E
Sbjct: 323 EKAKVELIEKEKVLNK---CRDELVRTTAQYDQASTKYTALEQKLKKLTEDLSCQRQNAE 379
Query: 281 QANKDLEEKEKQLTAT-EAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENN 457
A LE+K K+ + E++ R Q ++++ + + R Q+L +A+ +
Sbjct: 380 SARCSLEQKIKEKEKEFQEELSRQQRSFQTLDQECIQMKAR---LTQELQQAKNMHNVLQ 436
Query: 458 RMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVK 637
L + QQ E +++ +L A + + K +E+ R + ++ E + + +
Sbjct: 437 AELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSE 496
Query: 638 SGDAKISXLEXELKVVGNSL 697
++ LE ELK + L
Sbjct: 497 QKAREVCHLEAELKNIKQCL 516
Score = 41.9 bits (94), Expect = 0.002
Identities = 40/222 (18%), Positives = 90/222 (40%), Gaps = 7/222 (3%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
++ A ++ + + ++ EK+N + + Q + + + E ++ Q++
Sbjct: 2191 EEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIK 2250
Query: 248 EDLILNKNKLEQANKDLEEK-------EKQLTATEAEVAALNRKVQQIEEDLEKSEERSG 406
E+ L+ K+L E ++ + ATE + + Q+ +EK R
Sbjct: 2251 EESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSLDPPIEEEHQLRNSIEKLRARLE 2310
Query: 407 TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSR 586
++K L Q E+ +L+ R + E ++ + A L AE++ G+ + +
Sbjct: 2311 ADEKKQLCVLQQLKESEHHADLLKGRVENLERELEIARTNQEHAALEAENSKGEVETLKA 2370
Query: 587 KLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEV 712
K+ + L E V + ++ L EL+ + LE+
Sbjct: 2371 KIEGMTQSLRGLELDVVTIRSEKENLTNELQKEQERISELEI 2412
Score = 40.7 bits (91), Expect = 0.005
Identities = 35/150 (23%), Positives = 69/150 (46%), Gaps = 5/150 (3%)
Frame = +2
Query: 278 EQANKDLEEKEKQLTATEA--EVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADE 451
EQ + E E +L A ++ A L +V +E LE ++ + Q++ E Q E
Sbjct: 802 EQGSMPSERSECRLEADQSPKNSAILQNRVDSLEFSLESQKQMNSDLQKQCEELVQIKGE 861
Query: 452 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED---ELEVA 622
+ EN + ++ + + L ED + V+ L+ +E+ EL++
Sbjct: 862 ------IEENLMKAEQMHQSFVAETSQRISKLQEDTSAHQNVVAETLSALENKEKELQLL 915
Query: 623 EDRVKSGDAKISXLEXELKVVGNSLKSLEV 712
D+V++ A+I L+ ++ +SLK L++
Sbjct: 916 NDKVETEQAEIQELKKSNHLLEDSLKELQL 945
Score = 38.7 bits (86), Expect = 0.021
Identities = 41/179 (22%), Positives = 86/179 (48%), Gaps = 16/179 (8%)
Frame = +2
Query: 209 EVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNR-KVQQIE--ED 379
E++ ++KL EE L K +++ EE L AT + L + K+ ++
Sbjct: 2723 EIQTYREKLTSKEECLSSQKLEIDLLKSSKEELNNSLKATTQILEELKKTKMDNLKYVNQ 2782
Query: 380 LEKSEERSGTAQQKLLEA-QQSADENNRMCKVLEN-RAQQDEER--------MDQLTNQL 529
L+K ER+ + L+++ +Q +E + K L +A Q++++ +D+LT ++
Sbjct: 2783 LKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQEKQKTGTVMDTKVDELTTEI 2842
Query: 530 KEARLLAEDADGKSDEVSRK---LAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSL 697
KE + E+ ++DE K L ++LE A++ +++ A + + + G+ L
Sbjct: 2843 KELKETLEEKTKEADEYLDKYCSLLISHEKLEKAKEMLETQVAHLCSQQSKQDSRGSPL 2901
Score = 36.7 bits (81), Expect = 0.086
Identities = 50/183 (27%), Positives = 91/183 (49%), Gaps = 15/183 (8%)
Frame = +2
Query: 101 KKMQAMKLEKDNAM-DKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKL 277
++M+A ++ + D + QQ + +L EK+ V +L+K+ ++ L ++ +
Sbjct: 524 EEMKAKNTSQETMLRDLQEKINQQ--ENSLTLEKLKLAVADLEKQRDCSQDLLKKREHHI 581
Query: 278 EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQ-QKLLEAQQSADEN 454
EQ N L + EK+ ++A ++AL K ++ E EK+ ++ +KLL +S EN
Sbjct: 582 EQLNDKLSKTEKE---SKALLSALELKKKEYELKEEKTLFSCWKSENEKLLTQMESEKEN 638
Query: 455 -----NRM--C-KVLENRAQQDEERMDQL----TNQLKEARLLAEDADGKSDEV-SRKLA 595
N + C K + ++ + ER+ L N E R L D KS EV ++KLA
Sbjct: 639 LQSKINHLETCLKTQQIKSHEYNERVRTLEMDRENLSVEIRNLHNVLDSKSVEVETQKLA 698
Query: 596 FVE 604
++E
Sbjct: 699 YME 701
Score = 36.7 bits (81), Expect = 0.086
Identities = 25/118 (21%), Positives = 62/118 (52%), Gaps = 1/118 (0%)
Frame = +2
Query: 185 LRAEKVNEE-VRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKV 361
++AE++++ V E +++++++ED ++N + + LE KEK+L +V ++
Sbjct: 867 MKAEQMHQSFVAETSQRISKLQEDTSAHQNVVAETLSALENKEKELQLLNDKVETEQAEI 926
Query: 362 QQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKE 535
Q++++ E+ + ++ L ++ + E M ++ ++ EE + Q LKE
Sbjct: 927 QELKKSNHLLED---SLKELQLLSETLSLEKKEMSSIISLNKREIEE-LTQENGTLKE 980
Score = 36.3 bits (80), Expect = 0.11
Identities = 32/168 (19%), Positives = 73/168 (43%)
Frame = +2
Query: 161 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 340
EQ NL E + ++++ LQ K A +++ L + ++ + +LE + + +V
Sbjct: 2552 EQNLELRNLTVE-LEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKMSFVEKV 2610
Query: 341 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 520
+ K +++ ++ + +++ Q++L + E NR+ L+ ++ + DQL
Sbjct: 2611 NKMTAKETELQREMHEMAQKTAELQEEL------SGEKNRLAGELQLLLEEIKSSKDQLK 2664
Query: 521 NQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXL 664
E L + D + K V +E+ + R+ + K L
Sbjct: 2665 ELTLENSELKKSLDCMHKDQVEKEGKVREEIAEYQLRLHEAEKKHQAL 2712
Score = 35.1 bits (77), Expect = 0.26
Identities = 36/179 (20%), Positives = 74/179 (41%), Gaps = 4/179 (2%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKL--EKDNA-MDKADTC-EQQARDANLRAEKVNEEVRELQKKL 235
+ +A ++A + +Q KL EKDN K C E++ ++ E+ + KK
Sbjct: 1914 EHEALYLEADLEVVQTEKLCLEKDNENKQKVIVCLEEELSVVTSERNQLRGELDTMSKKT 1973
Query: 236 AQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQ 415
+++ K K ++ E + EAEV +Q + D+ + + Q
Sbjct: 1974 TALDQLSEKMKEKTQELESHQSECLHCIQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQ 2033
Query: 416 QKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKL 592
+KL ++ + + LEN+ Q + + L + + + ++D + VS+ L
Sbjct: 2034 EKLQSLEKDSQALSLTKCELENQIAQLNKEKELLVKESESLQARLSESDYEKLNVSKAL 2092
Score = 33.9 bits (74), Expect = 0.60
Identities = 32/176 (18%), Positives = 78/176 (44%), Gaps = 15/176 (8%)
Frame = +2
Query: 134 NAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEK 313
N + + + + + L A++ + LQ ++ +E L K Q N DL+++ +
Sbjct: 798 NIIGEQGSMPSERSECRLEADQSPKNSAILQNRVDSLEFSLESQK----QMNSDLQKQCE 853
Query: 314 QLTATEAEVAALNRKVQQIEED--------LEKSEERSGTAQQKLLEAQQSADENNRMCK 469
+L + E+ K +Q+ + + K +E + Q + E + + + +
Sbjct: 854 ELVQIKGEIEENLMKAEQMHQSFVAETSQRISKLQEDTSAHQNVVAETLSALENKEKELQ 913
Query: 470 VLENRAQQDEERMDQLT-------NQLKEARLLAEDADGKSDEVSRKLAFVEDELE 616
+L ++ + ++ + +L + LKE +LL+E + E+S ++ + E+E
Sbjct: 914 LLNDKVETEQAEIQELKKSNHLLEDSLKELQLLSETLSLEKKEMSSIISLNKREIE 969
>U19769-1|AAA82889.1| 3210|Homo sapiens CENP-F kinetochore protein
protein.
Length = 3210
Score = 57.6 bits (133), Expect = 4e-08
Identities = 46/222 (20%), Positives = 101/222 (45%), Gaps = 14/222 (6%)
Frame = +2
Query: 89 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVREL-------QKKLAQVE 247
+ +K+K Q ++ + + E + ++ + ++ +V EL Q+KL +E
Sbjct: 2078 EKMKEKTQELESHQSECLHCIQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLE 2137
Query: 248 ED---LILNK----NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSG 406
+D L L K N++ Q NK+ E K+ + +A ++ + + + + LE + G
Sbjct: 2138 KDSQALSLTKCELENQIAQLNKEKELLVKESESLQARLSESDYEKLNVSKALEAALVEKG 2197
Query: 407 TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSR 586
+L Q+ + R + L R + DE++ + +LKE + K + + R
Sbjct: 2198 EFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLER 2257
Query: 587 KLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEV 712
+L E+ E+ ++ A++ L+ +++ + SLK E+
Sbjct: 2258 ELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFEL 2299
Score = 52.0 bits (119), Expect = 2e-06
Identities = 47/236 (19%), Positives = 111/236 (47%), Gaps = 28/236 (11%)
Frame = +2
Query: 89 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 268
D++K K++ ++ E + + + A ++ E + ++ E+ + L E DL+ +
Sbjct: 2246 DSLKDKVENLERELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLR 2305
Query: 269 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTA------------ 412
++ E K ++EK+ QL+ + +++ +++ E+ + +E S TA
Sbjct: 2306 SEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELN 2365
Query: 413 --------QQKLLEA-QQSAD----ENNRMCKVLEN---RAQQDEERMDQLTNQLKEARL 544
Q++++A +QS D E +++ +E R + DE++ + QLKE+
Sbjct: 2366 EAVAALCGDQEIMKATEQSLDPPIEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESEH 2425
Query: 545 LAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEV 712
A+ G+ + + R+L E A ++ ++ L+ +++ + SL+ LE+
Sbjct: 2426 HADLLKGRVENLERELEIARTNQEHAALEAENSKGEVETLKAKIEGMTQSLRGLEL 2481
Score = 48.4 bits (110), Expect = 3e-05
Identities = 40/200 (20%), Positives = 90/200 (45%), Gaps = 1/200 (0%)
Frame = +2
Query: 101 KKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLE 280
+K + +EK+ ++K C + + ++ + + L++KL ++ EDL + E
Sbjct: 323 EKAKVELIEKEKVLNK---CRDELVRTTAQYDQASTKYTALEQKLKKLTEDLSCQRQNAE 379
Query: 281 QANKDLEEKEKQLTAT-EAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENN 457
A LE+K K+ + E++ R Q ++++ + + R Q+L +A+ +
Sbjct: 380 SARCSLEQKIKEKEKEFQEELSRQQRSFQTLDQECIQMKAR---LTQELQQAKNMHNVLQ 436
Query: 458 RMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVK 637
L + QQ E +++ +L A + + K +E+ R + ++ E + + +
Sbjct: 437 AELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSE 496
Query: 638 SGDAKISXLEXELKVVGNSL 697
++ LE ELK + L
Sbjct: 497 QKAREVCHLEAELKNIKQCL 516
Score = 41.9 bits (94), Expect = 0.002
Identities = 40/222 (18%), Positives = 90/222 (40%), Gaps = 7/222 (3%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
++ A ++ + + ++ EK+N + + Q + + + E ++ Q++
Sbjct: 2288 EEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIK 2347
Query: 248 EDLILNKNKLEQANKDLEEK-------EKQLTATEAEVAALNRKVQQIEEDLEKSEERSG 406
E+ L+ K+L E ++ + ATE + + Q+ +EK R
Sbjct: 2348 EESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSLDPPIEEEHQLRNSIEKLRARLE 2407
Query: 407 TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSR 586
++K L Q E+ +L+ R + E ++ + A L AE++ G+ + +
Sbjct: 2408 ADEKKQLCVLQQLKESEHHADLLKGRVENLERELEIARTNQEHAALEAENSKGEVETLKA 2467
Query: 587 KLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEV 712
K+ + L E V + ++ L EL+ + LE+
Sbjct: 2468 KIEGMTQSLRGLELDVVTIRSEKEDLTNELQKEQERISELEI 2509
Score = 40.7 bits (91), Expect = 0.005
Identities = 35/150 (23%), Positives = 69/150 (46%), Gaps = 5/150 (3%)
Frame = +2
Query: 278 EQANKDLEEKEKQLTATEA--EVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADE 451
EQ + E E +L A ++ A L +V +E LE ++ + Q++ E Q E
Sbjct: 803 EQGSMPSERSECRLEADQSPKNSAILQNRVDSLEFSLESQKQMNSDLQKQCEELVQIKGE 862
Query: 452 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED---ELEVA 622
+ EN + ++ + + L ED + V+ L+ +E+ EL++
Sbjct: 863 ------IEENLMKAEQMHQSFVAETSQRISKLQEDTSAHQNVVAETLSALENKEKELQLL 916
Query: 623 EDRVKSGDAKISXLEXELKVVGNSLKSLEV 712
D+V++ A+I L+ ++ +SLK L++
Sbjct: 917 NDKVETEQAEIQELKKSNHLLEDSLKELQL 946
Score = 38.7 bits (86), Expect = 0.021
Identities = 41/179 (22%), Positives = 86/179 (48%), Gaps = 16/179 (8%)
Frame = +2
Query: 209 EVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNR-KVQQIE--ED 379
E++ ++KL EE L K +++ EE L AT + L + K+ ++
Sbjct: 2820 EIQTYREKLTSKEECLSSQKLEIDLLKSSKEELNNSLKATTQILEELKKTKMDNLKYVNQ 2879
Query: 380 LEKSEERSGTAQQKLLEA-QQSADENNRMCKVLEN-RAQQDEER--------MDQLTNQL 529
L+K ER+ + L+++ +Q +E + K L +A Q++++ +D+LT ++
Sbjct: 2880 LKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQEKQKTGTVMDTKVDELTTEI 2939
Query: 530 KEARLLAEDADGKSDEVSRK---LAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSL 697
KE + E+ ++DE K L ++LE A++ +++ A + + + G+ L
Sbjct: 2940 KELKETLEEKTKEADEYLDKYCSLLISHEKLEKAKEMLETQVAHLCSQQSKQDSRGSPL 2998
Score = 37.5 bits (83), Expect = 0.049
Identities = 51/184 (27%), Positives = 91/184 (49%), Gaps = 16/184 (8%)
Frame = +2
Query: 101 KKMQAMKLEKDNAM-DKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKL 277
++M+A ++ + D + QQ + +L EK+ V +L+K+ ++ L ++ +
Sbjct: 524 EEMKAKNTSQETMLRDLQEKINQQ--ENSLTLEKLKLAVADLEKQRDCSQDLLKKREHHI 581
Query: 278 EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERS--GTAQQKLLEAQQSADE 451
EQ N L + EK+ ++A ++AL K ++ EE E+ S + +KLL +S E
Sbjct: 582 EQLNDKLSKTEKE---SKALLSALELKKKEYEELKEEKTLFSCWKSENEKLLTQMESEKE 638
Query: 452 N-----NRM--C-KVLENRAQQDEERMDQL----TNQLKEARLLAEDADGKSDEV-SRKL 592
N N + C K + ++ + ER+ L N E R L D KS EV ++KL
Sbjct: 639 NLQSKINHLETCLKTQQIKSHEYNERVRTLEMDRENLSVEIRNLHNVLDSKSVEVETQKL 698
Query: 593 AFVE 604
A++E
Sbjct: 699 AYME 702
Score = 36.7 bits (81), Expect = 0.086
Identities = 25/118 (21%), Positives = 62/118 (52%), Gaps = 1/118 (0%)
Frame = +2
Query: 185 LRAEKVNEE-VRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKV 361
++AE++++ V E +++++++ED ++N + + LE KEK+L +V ++
Sbjct: 868 MKAEQMHQSFVAETSQRISKLQEDTSAHQNVVAETLSALENKEKELQLLNDKVETEQAEI 927
Query: 362 QQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKE 535
Q++++ E+ + ++ L ++ + E M ++ ++ EE + Q LKE
Sbjct: 928 QELKKSNHLLED---SLKELQLLSETLSLEKKEMSSIISLNKREIEE-LTQENGTLKE 981
Score = 36.3 bits (80), Expect = 0.11
Identities = 32/168 (19%), Positives = 73/168 (43%)
Frame = +2
Query: 161 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 340
EQ NL E + ++++ LQ K A +++ L + ++ + +LE + + +V
Sbjct: 2649 EQNLELRNLTVE-LEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKMSFVEKV 2707
Query: 341 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 520
+ K +++ ++ + +++ Q++L + E NR+ L+ ++ + DQL
Sbjct: 2708 NKMTAKETELQREMHEMAQKTAELQEEL------SGEKNRLAGELQLLLEEIKSSKDQLK 2761
Query: 521 NQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXL 664
E L + D + K V +E+ + R+ + K L
Sbjct: 2762 ELTLENSELKKSLDCMHKDQVEKEGKVREEIAEYQLRLHEAEKKHQAL 2809
Score = 35.1 bits (77), Expect = 0.26
Identities = 36/179 (20%), Positives = 74/179 (41%), Gaps = 4/179 (2%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKL--EKDNA-MDKADTC-EQQARDANLRAEKVNEEVRELQKKL 235
+ +A ++A + +Q KL EKDN K C E++ ++ E+ + KK
Sbjct: 2011 EHEALYLEADLEVVQTEKLCLEKDNENKQKVIVCLEEELSVVTSERNQLRGELDTMSKKT 2070
Query: 236 AQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQ 415
+++ K K ++ E + EAEV +Q + D+ + + Q
Sbjct: 2071 TALDQLSEKMKEKTQELESHQSECLHCIQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQ 2130
Query: 416 QKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKL 592
+KL ++ + + LEN+ Q + + L + + + ++D + VS+ L
Sbjct: 2131 EKLQSLEKDSQALSLTKCELENQIAQLNKEKELLVKESESLQARLSESDYEKLNVSKAL 2189
Score = 33.9 bits (74), Expect = 0.60
Identities = 32/176 (18%), Positives = 78/176 (44%), Gaps = 15/176 (8%)
Frame = +2
Query: 134 NAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEK 313
N + + + + + L A++ + LQ ++ +E L K Q N DL+++ +
Sbjct: 799 NIIGEQGSMPSERSECRLEADQSPKNSAILQNRVDSLEFSLESQK----QMNSDLQKQCE 854
Query: 314 QLTATEAEVAALNRKVQQIEED--------LEKSEERSGTAQQKLLEAQQSADENNRMCK 469
+L + E+ K +Q+ + + K +E + Q + E + + + +
Sbjct: 855 ELVQIKGEIEENLMKAEQMHQSFVAETSQRISKLQEDTSAHQNVVAETLSALENKEKELQ 914
Query: 470 VLENRAQQDEERMDQLT-------NQLKEARLLAEDADGKSDEVSRKLAFVEDELE 616
+L ++ + ++ + +L + LKE +LL+E + E+S ++ + E+E
Sbjct: 915 LLNDKVETEQAEIQELKKSNHLLEDSLKELQLLSETLSLEKKEMSSIISLNKREIE 970
>AL445666-1|CAH71810.1| 3114|Homo sapiens centromere protein F,
350/400ka (mitosin) protein.
Length = 3114
Score = 57.6 bits (133), Expect = 4e-08
Identities = 46/222 (20%), Positives = 101/222 (45%), Gaps = 14/222 (6%)
Frame = +2
Query: 89 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVREL-------QKKLAQVE 247
+ +K+K Q ++ + + E + ++ + ++ +V EL Q+KL +E
Sbjct: 1982 EKMKEKTQELESHQSECLHCIQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLE 2041
Query: 248 ED---LILNK----NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSG 406
+D L L K N++ Q NK+ E K+ + +A ++ + + + + LE + G
Sbjct: 2042 KDSQALSLTKCELENQIAQLNKEKELLVKESESLQARLSESDYEKLNVSKALEAALVEKG 2101
Query: 407 TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSR 586
+L Q+ + R + L R + DE++ + +LKE + K + + R
Sbjct: 2102 EFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLER 2161
Query: 587 KLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEV 712
+L E+ E+ ++ A++ L+ +++ + SLK E+
Sbjct: 2162 ELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFEL 2203
Score = 52.0 bits (119), Expect = 2e-06
Identities = 47/236 (19%), Positives = 111/236 (47%), Gaps = 28/236 (11%)
Frame = +2
Query: 89 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 268
D++K K++ ++ E + + + A ++ E + ++ E+ + L E DL+ +
Sbjct: 2150 DSLKDKVENLERELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLR 2209
Query: 269 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTA------------ 412
++ E K ++EK+ QL+ + +++ +++ E+ + +E S TA
Sbjct: 2210 SEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELN 2269
Query: 413 --------QQKLLEA-QQSAD----ENNRMCKVLEN---RAQQDEERMDQLTNQLKEARL 544
Q++++A +QS D E +++ +E R + DE++ + QLKE+
Sbjct: 2270 EAVAALCGDQEIMKATEQSLDPPIEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESEH 2329
Query: 545 LAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEV 712
A+ G+ + + R+L E A ++ ++ L+ +++ + SL+ LE+
Sbjct: 2330 HADLLKGRVENLERELEIARTNQEHAALEAENSKGEVETLKAKIEGMTQSLRGLEL 2385
Score = 48.4 bits (110), Expect = 3e-05
Identities = 40/200 (20%), Positives = 90/200 (45%), Gaps = 1/200 (0%)
Frame = +2
Query: 101 KKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLE 280
+K + +EK+ ++K C + + ++ + + L++KL ++ EDL + E
Sbjct: 323 EKAKVELIEKEKVLNK---CRDELVRTTAQYDQASTKYTALEQKLKKLTEDLSCQRQNAE 379
Query: 281 QANKDLEEKEKQLTAT-EAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENN 457
A LE+K K+ + E++ R Q ++++ + + R Q+L +A+ +
Sbjct: 380 SARCSLEQKIKEKEKEFQEELSRQQRSFQTLDQECIQMKAR---LTQELQQAKNMHNVLQ 436
Query: 458 RMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVK 637
L + QQ E +++ +L A + + K +E+ R + ++ E + + +
Sbjct: 437 AELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSE 496
Query: 638 SGDAKISXLEXELKVVGNSL 697
++ LE ELK + L
Sbjct: 497 QKAREVCHLEAELKNIKQCL 516
Score = 41.9 bits (94), Expect = 0.002
Identities = 40/222 (18%), Positives = 90/222 (40%), Gaps = 7/222 (3%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
++ A ++ + + ++ EK+N + + Q + + + E ++ Q++
Sbjct: 2192 EEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIK 2251
Query: 248 EDLILNKNKLEQANKDLEEK-------EKQLTATEAEVAALNRKVQQIEEDLEKSEERSG 406
E+ L+ K+L E ++ + ATE + + Q+ +EK R
Sbjct: 2252 EESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSLDPPIEEEHQLRNSIEKLRARLE 2311
Query: 407 TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSR 586
++K L Q E+ +L+ R + E ++ + A L AE++ G+ + +
Sbjct: 2312 ADEKKQLCVLQQLKESEHHADLLKGRVENLERELEIARTNQEHAALEAENSKGEVETLKA 2371
Query: 587 KLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEV 712
K+ + L E V + ++ L EL+ + LE+
Sbjct: 2372 KIEGMTQSLRGLELDVVTIRSEKENLTNELQKEQERISELEI 2413
Score = 40.7 bits (91), Expect = 0.005
Identities = 35/150 (23%), Positives = 69/150 (46%), Gaps = 5/150 (3%)
Frame = +2
Query: 278 EQANKDLEEKEKQLTATEA--EVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADE 451
EQ + E E +L A ++ A L +V +E LE ++ + Q++ E Q E
Sbjct: 803 EQGSMPSERSECRLEADQSPKNSAILQNRVDSLEFSLESQKQMNSDLQKQCEELVQIKGE 862
Query: 452 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED---ELEVA 622
+ EN + ++ + + L ED + V+ L+ +E+ EL++
Sbjct: 863 ------IEENLMKAEQMHQSFVAETSQRISKLQEDTSAHQNVVAETLSALENKEKELQLL 916
Query: 623 EDRVKSGDAKISXLEXELKVVGNSLKSLEV 712
D+V++ A+I L+ ++ +SLK L++
Sbjct: 917 NDKVETEQAEIQELKKSNHLLEDSLKELQL 946
Score = 38.7 bits (86), Expect = 0.021
Identities = 41/179 (22%), Positives = 86/179 (48%), Gaps = 16/179 (8%)
Frame = +2
Query: 209 EVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNR-KVQQIE--ED 379
E++ ++KL EE L K +++ EE L AT + L + K+ ++
Sbjct: 2724 EIQTYREKLTSKEECLSSQKLEIDLLKSSKEELNNSLKATTQILEELKKTKMDNLKYVNQ 2783
Query: 380 LEKSEERSGTAQQKLLEA-QQSADENNRMCKVLEN-RAQQDEER--------MDQLTNQL 529
L+K ER+ + L+++ +Q +E + K L +A Q++++ +D+LT ++
Sbjct: 2784 LKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQEKQKTGTVMDTKVDELTTEI 2843
Query: 530 KEARLLAEDADGKSDEVSRK---LAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSL 697
KE + E+ ++DE K L ++LE A++ +++ A + + + G+ L
Sbjct: 2844 KELKETLEEKTKEADEYLDKYCSLLISHEKLEKAKEMLETQVAHLCSQQSKQDSRGSPL 2902
Score = 37.5 bits (83), Expect = 0.049
Identities = 51/184 (27%), Positives = 91/184 (49%), Gaps = 16/184 (8%)
Frame = +2
Query: 101 KKMQAMKLEKDNAM-DKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKL 277
++M+A ++ + D + QQ + +L EK+ V +L+K+ ++ L ++ +
Sbjct: 524 EEMKAKNTSQETMLRDLQEKINQQ--ENSLTLEKLKLAVADLEKQRDCSQDLLKKREHHI 581
Query: 278 EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERS--GTAQQKLLEAQQSADE 451
EQ N L + EK+ ++A ++AL K ++ EE E+ S + +KLL +S E
Sbjct: 582 EQLNDKLSKTEKE---SKALLSALELKKKEYEELKEEKTLFSCWKSENEKLLTQMESEKE 638
Query: 452 N-----NRM--C-KVLENRAQQDEERMDQL----TNQLKEARLLAEDADGKSDEV-SRKL 592
N N + C K + ++ + ER+ L N E R L D KS EV ++KL
Sbjct: 639 NLQSKINHLETCLKTQQIKSHEYNERVRTLEMDRENLSVEIRNLHNVLDSKSVEVETQKL 698
Query: 593 AFVE 604
A++E
Sbjct: 699 AYME 702
Score = 36.7 bits (81), Expect = 0.086
Identities = 25/118 (21%), Positives = 62/118 (52%), Gaps = 1/118 (0%)
Frame = +2
Query: 185 LRAEKVNEE-VRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKV 361
++AE++++ V E +++++++ED ++N + + LE KEK+L +V ++
Sbjct: 868 MKAEQMHQSFVAETSQRISKLQEDTSAHQNVVAETLSALENKEKELQLLNDKVETEQAEI 927
Query: 362 QQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKE 535
Q++++ E+ + ++ L ++ + E M ++ ++ EE + Q LKE
Sbjct: 928 QELKKSNHLLED---SLKELQLLSETLSLEKKEMSSIISLNKREIEE-LTQENGTLKE 981
Score = 36.3 bits (80), Expect = 0.11
Identities = 32/168 (19%), Positives = 73/168 (43%)
Frame = +2
Query: 161 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 340
EQ NL E + ++++ LQ K A +++ L + ++ + +LE + + +V
Sbjct: 2553 EQNLELRNLTVE-LEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKMSFVEKV 2611
Query: 341 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 520
+ K +++ ++ + +++ Q++L + E NR+ L+ ++ + DQL
Sbjct: 2612 NKMTAKETELQREMHEMAQKTAELQEEL------SGEKNRLAGELQLLLEEIKSSKDQLK 2665
Query: 521 NQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXL 664
E L + D + K V +E+ + R+ + K L
Sbjct: 2666 ELTLENSELKKSLDCMHKDQVEKEGKVREEIAEYQLRLHEAEKKHQAL 2713
Score = 35.1 bits (77), Expect = 0.26
Identities = 36/179 (20%), Positives = 74/179 (41%), Gaps = 4/179 (2%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKL--EKDNA-MDKADTC-EQQARDANLRAEKVNEEVRELQKKL 235
+ +A ++A + +Q KL EKDN K C E++ ++ E+ + KK
Sbjct: 1915 EHEALYLEADLEVVQTEKLCLEKDNENKQKVIVCLEEELSVVTSERNQLRGELDTMSKKT 1974
Query: 236 AQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQ 415
+++ K K ++ E + EAEV +Q + D+ + + Q
Sbjct: 1975 TALDQLSEKMKEKTQELESHQSECLHCIQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQ 2034
Query: 416 QKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKL 592
+KL ++ + + LEN+ Q + + L + + + ++D + VS+ L
Sbjct: 2035 EKLQSLEKDSQALSLTKCELENQIAQLNKEKELLVKESESLQARLSESDYEKLNVSKAL 2093
Score = 33.9 bits (74), Expect = 0.60
Identities = 32/176 (18%), Positives = 78/176 (44%), Gaps = 15/176 (8%)
Frame = +2
Query: 134 NAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEK 313
N + + + + + L A++ + LQ ++ +E L K Q N DL+++ +
Sbjct: 799 NIIGEQGSMPSERSECRLEADQSPKNSAILQNRVDSLEFSLESQK----QMNSDLQKQCE 854
Query: 314 QLTATEAEVAALNRKVQQIEED--------LEKSEERSGTAQQKLLEAQQSADENNRMCK 469
+L + E+ K +Q+ + + K +E + Q + E + + + +
Sbjct: 855 ELVQIKGEIEENLMKAEQMHQSFVAETSQRISKLQEDTSAHQNVVAETLSALENKEKELQ 914
Query: 470 VLENRAQQDEERMDQLT-------NQLKEARLLAEDADGKSDEVSRKLAFVEDELE 616
+L ++ + ++ + +L + LKE +LL+E + E+S ++ + E+E
Sbjct: 915 LLNDKVETEQAEIQELKKSNHLLEDSLKELQLLSETLSLEKKEMSSIISLNKREIE 970
>AL445305-6|CAH73032.1| 3114|Homo sapiens centromere protein F,
350/400ka (mitosin) protein.
Length = 3114
Score = 57.6 bits (133), Expect = 4e-08
Identities = 46/222 (20%), Positives = 101/222 (45%), Gaps = 14/222 (6%)
Frame = +2
Query: 89 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVREL-------QKKLAQVE 247
+ +K+K Q ++ + + E + ++ + ++ +V EL Q+KL +E
Sbjct: 1982 EKMKEKTQELESHQSECLHCIQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLE 2041
Query: 248 ED---LILNK----NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSG 406
+D L L K N++ Q NK+ E K+ + +A ++ + + + + LE + G
Sbjct: 2042 KDSQALSLTKCELENQIAQLNKEKELLVKESESLQARLSESDYEKLNVSKALEAALVEKG 2101
Query: 407 TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSR 586
+L Q+ + R + L R + DE++ + +LKE + K + + R
Sbjct: 2102 EFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLER 2161
Query: 587 KLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEV 712
+L E+ E+ ++ A++ L+ +++ + SLK E+
Sbjct: 2162 ELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFEL 2203
Score = 52.0 bits (119), Expect = 2e-06
Identities = 47/236 (19%), Positives = 111/236 (47%), Gaps = 28/236 (11%)
Frame = +2
Query: 89 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 268
D++K K++ ++ E + + + A ++ E + ++ E+ + L E DL+ +
Sbjct: 2150 DSLKDKVENLERELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLR 2209
Query: 269 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTA------------ 412
++ E K ++EK+ QL+ + +++ +++ E+ + +E S TA
Sbjct: 2210 SEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELN 2269
Query: 413 --------QQKLLEA-QQSAD----ENNRMCKVLEN---RAQQDEERMDQLTNQLKEARL 544
Q++++A +QS D E +++ +E R + DE++ + QLKE+
Sbjct: 2270 EAVAALCGDQEIMKATEQSLDPPIEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESEH 2329
Query: 545 LAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEV 712
A+ G+ + + R+L E A ++ ++ L+ +++ + SL+ LE+
Sbjct: 2330 HADLLKGRVENLERELEIARTNQEHAALEAENSKGEVETLKAKIEGMTQSLRGLEL 2385
Score = 48.4 bits (110), Expect = 3e-05
Identities = 40/200 (20%), Positives = 90/200 (45%), Gaps = 1/200 (0%)
Frame = +2
Query: 101 KKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLE 280
+K + +EK+ ++K C + + ++ + + L++KL ++ EDL + E
Sbjct: 323 EKAKVELIEKEKVLNK---CRDELVRTTAQYDQASTKYTALEQKLKKLTEDLSCQRQNAE 379
Query: 281 QANKDLEEKEKQLTAT-EAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENN 457
A LE+K K+ + E++ R Q ++++ + + R Q+L +A+ +
Sbjct: 380 SARCSLEQKIKEKEKEFQEELSRQQRSFQTLDQECIQMKAR---LTQELQQAKNMHNVLQ 436
Query: 458 RMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVK 637
L + QQ E +++ +L A + + K +E+ R + ++ E + + +
Sbjct: 437 AELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSE 496
Query: 638 SGDAKISXLEXELKVVGNSL 697
++ LE ELK + L
Sbjct: 497 QKAREVCHLEAELKNIKQCL 516
Score = 41.9 bits (94), Expect = 0.002
Identities = 40/222 (18%), Positives = 90/222 (40%), Gaps = 7/222 (3%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
++ A ++ + + ++ EK+N + + Q + + + E ++ Q++
Sbjct: 2192 EEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIK 2251
Query: 248 EDLILNKNKLEQANKDLEEK-------EKQLTATEAEVAALNRKVQQIEEDLEKSEERSG 406
E+ L+ K+L E ++ + ATE + + Q+ +EK R
Sbjct: 2252 EESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSLDPPIEEEHQLRNSIEKLRARLE 2311
Query: 407 TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSR 586
++K L Q E+ +L+ R + E ++ + A L AE++ G+ + +
Sbjct: 2312 ADEKKQLCVLQQLKESEHHADLLKGRVENLERELEIARTNQEHAALEAENSKGEVETLKA 2371
Query: 587 KLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEV 712
K+ + L E V + ++ L EL+ + LE+
Sbjct: 2372 KIEGMTQSLRGLELDVVTIRSEKENLTNELQKEQERISELEI 2413
Score = 40.7 bits (91), Expect = 0.005
Identities = 35/150 (23%), Positives = 69/150 (46%), Gaps = 5/150 (3%)
Frame = +2
Query: 278 EQANKDLEEKEKQLTATEA--EVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADE 451
EQ + E E +L A ++ A L +V +E LE ++ + Q++ E Q E
Sbjct: 803 EQGSMPSERSECRLEADQSPKNSAILQNRVDSLEFSLESQKQMNSDLQKQCEELVQIKGE 862
Query: 452 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED---ELEVA 622
+ EN + ++ + + L ED + V+ L+ +E+ EL++
Sbjct: 863 ------IEENLMKAEQMHQSFVAETSQRISKLQEDTSAHQNVVAETLSALENKEKELQLL 916
Query: 623 EDRVKSGDAKISXLEXELKVVGNSLKSLEV 712
D+V++ A+I L+ ++ +SLK L++
Sbjct: 917 NDKVETEQAEIQELKKSNHLLEDSLKELQL 946
Score = 38.7 bits (86), Expect = 0.021
Identities = 41/179 (22%), Positives = 86/179 (48%), Gaps = 16/179 (8%)
Frame = +2
Query: 209 EVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNR-KVQQIE--ED 379
E++ ++KL EE L K +++ EE L AT + L + K+ ++
Sbjct: 2724 EIQTYREKLTSKEECLSSQKLEIDLLKSSKEELNNSLKATTQILEELKKTKMDNLKYVNQ 2783
Query: 380 LEKSEERSGTAQQKLLEA-QQSADENNRMCKVLEN-RAQQDEER--------MDQLTNQL 529
L+K ER+ + L+++ +Q +E + K L +A Q++++ +D+LT ++
Sbjct: 2784 LKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQEKQKTGTVMDTKVDELTTEI 2843
Query: 530 KEARLLAEDADGKSDEVSRK---LAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSL 697
KE + E+ ++DE K L ++LE A++ +++ A + + + G+ L
Sbjct: 2844 KELKETLEEKTKEADEYLDKYCSLLISHEKLEKAKEMLETQVAHLCSQQSKQDSRGSPL 2902
Score = 37.5 bits (83), Expect = 0.049
Identities = 51/184 (27%), Positives = 91/184 (49%), Gaps = 16/184 (8%)
Frame = +2
Query: 101 KKMQAMKLEKDNAM-DKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKL 277
++M+A ++ + D + QQ + +L EK+ V +L+K+ ++ L ++ +
Sbjct: 524 EEMKAKNTSQETMLRDLQEKINQQ--ENSLTLEKLKLAVADLEKQRDCSQDLLKKREHHI 581
Query: 278 EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERS--GTAQQKLLEAQQSADE 451
EQ N L + EK+ ++A ++AL K ++ EE E+ S + +KLL +S E
Sbjct: 582 EQLNDKLSKTEKE---SKALLSALELKKKEYEELKEEKTLFSCWKSENEKLLTQMESEKE 638
Query: 452 N-----NRM--C-KVLENRAQQDEERMDQL----TNQLKEARLLAEDADGKSDEV-SRKL 592
N N + C K + ++ + ER+ L N E R L D KS EV ++KL
Sbjct: 639 NLQSKINHLETCLKTQQIKSHEYNERVRTLEMDRENLSVEIRNLHNVLDSKSVEVETQKL 698
Query: 593 AFVE 604
A++E
Sbjct: 699 AYME 702
Score = 36.7 bits (81), Expect = 0.086
Identities = 25/118 (21%), Positives = 62/118 (52%), Gaps = 1/118 (0%)
Frame = +2
Query: 185 LRAEKVNEE-VRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKV 361
++AE++++ V E +++++++ED ++N + + LE KEK+L +V ++
Sbjct: 868 MKAEQMHQSFVAETSQRISKLQEDTSAHQNVVAETLSALENKEKELQLLNDKVETEQAEI 927
Query: 362 QQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKE 535
Q++++ E+ + ++ L ++ + E M ++ ++ EE + Q LKE
Sbjct: 928 QELKKSNHLLED---SLKELQLLSETLSLEKKEMSSIISLNKREIEE-LTQENGTLKE 981
Score = 36.3 bits (80), Expect = 0.11
Identities = 32/168 (19%), Positives = 73/168 (43%)
Frame = +2
Query: 161 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 340
EQ NL E + ++++ LQ K A +++ L + ++ + +LE + + +V
Sbjct: 2553 EQNLELRNLTVE-LEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKMSFVEKV 2611
Query: 341 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 520
+ K +++ ++ + +++ Q++L + E NR+ L+ ++ + DQL
Sbjct: 2612 NKMTAKETELQREMHEMAQKTAELQEEL------SGEKNRLAGELQLLLEEIKSSKDQLK 2665
Query: 521 NQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXL 664
E L + D + K V +E+ + R+ + K L
Sbjct: 2666 ELTLENSELKKSLDCMHKDQVEKEGKVREEIAEYQLRLHEAEKKHQAL 2713
Score = 35.1 bits (77), Expect = 0.26
Identities = 36/179 (20%), Positives = 74/179 (41%), Gaps = 4/179 (2%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKL--EKDNA-MDKADTC-EQQARDANLRAEKVNEEVRELQKKL 235
+ +A ++A + +Q KL EKDN K C E++ ++ E+ + KK
Sbjct: 1915 EHEALYLEADLEVVQTEKLCLEKDNENKQKVIVCLEEELSVVTSERNQLRGELDTMSKKT 1974
Query: 236 AQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQ 415
+++ K K ++ E + EAEV +Q + D+ + + Q
Sbjct: 1975 TALDQLSEKMKEKTQELESHQSECLHCIQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQ 2034
Query: 416 QKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKL 592
+KL ++ + + LEN+ Q + + L + + + ++D + VS+ L
Sbjct: 2035 EKLQSLEKDSQALSLTKCELENQIAQLNKEKELLVKESESLQARLSESDYEKLNVSKAL 2093
Score = 33.9 bits (74), Expect = 0.60
Identities = 32/176 (18%), Positives = 78/176 (44%), Gaps = 15/176 (8%)
Frame = +2
Query: 134 NAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEK 313
N + + + + + L A++ + LQ ++ +E L K Q N DL+++ +
Sbjct: 799 NIIGEQGSMPSERSECRLEADQSPKNSAILQNRVDSLEFSLESQK----QMNSDLQKQCE 854
Query: 314 QLTATEAEVAALNRKVQQIEED--------LEKSEERSGTAQQKLLEAQQSADENNRMCK 469
+L + E+ K +Q+ + + K +E + Q + E + + + +
Sbjct: 855 ELVQIKGEIEENLMKAEQMHQSFVAETSQRISKLQEDTSAHQNVVAETLSALENKEKELQ 914
Query: 470 VLENRAQQDEERMDQLT-------NQLKEARLLAEDADGKSDEVSRKLAFVEDELE 616
+L ++ + ++ + +L + LKE +LL+E + E+S ++ + E+E
Sbjct: 915 LLNDKVETEQAEIQELKKSNHLLEDSLKELQLLSETLSLEKKEMSSIISLNKREIE 970
>D00943-1|BAA00791.1| 1939|Homo sapiens cardiac alpha-myosin heavy
chain protein.
Length = 1939
Score = 57.2 bits (132), Expect = 6e-08
Identities = 59/233 (25%), Positives = 107/233 (45%), Gaps = 18/233 (7%)
Frame = +2
Query: 86 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVN----EEVRELQKKLAQVEE- 250
+ +K+K++ K E +D + +Q A EKV+ ++ E + KL + +
Sbjct: 1212 LQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRS 1271
Query: 251 --DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNR---KVQQIEEDLEKSEERSGTAQ 415
D + KL+ N +L +QL EA ++ L R Q EDL++ E G A+
Sbjct: 1272 LNDFTTQRAKLQTENGELS---RQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAK 1328
Query: 416 QKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL-LAE-------DADGKS 571
L A QSA + C +L + +++ E +L L +A +A+ DA ++
Sbjct: 1329 NALAHALQSARHD---CDLLREQYEEETEAKAELQRVLSKANSEVAQCRTKYETDAIQRT 1385
Query: 572 DEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXKAN 730
+E+ + L+ AE+ V++ +AK S LE + N ++ L V ++N
Sbjct: 1386 EELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSN 1438
Score = 52.0 bits (119), Expect = 2e-06
Identities = 45/202 (22%), Positives = 86/202 (42%), Gaps = 12/202 (5%)
Frame = +2
Query: 161 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 340
+ + D + E+ N L KK ++ L K K E++ +LE +K+ + E+
Sbjct: 1424 QNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTEL 1483
Query: 341 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 520
L ++ E LE + + Q+++ + + E + LE +Q E +L
Sbjct: 1484 FKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQ 1543
Query: 521 NQLKEARLLAEDADGK-----------SDEVSRKLAFVEDELEVAE-DRVKSGDAKISXL 664
+ L+EA E +GK E+ RKLA ++E+E A+ + + D+ + L
Sbjct: 1544 SALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSL 1603
Query: 665 EXELKVVGNSLKSLEVSEXKAN 730
+ E + L+ + E N
Sbjct: 1604 DAETRSRNEVLRVKKKMEGDLN 1625
Score = 52.0 bits (119), Expect = 2e-06
Identities = 50/233 (21%), Positives = 107/233 (45%), Gaps = 19/233 (8%)
Frame = +2
Query: 86 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAE-KVNEEVRELQKKLAQVEEDLIL 262
++ ++K+++ KLE +A+++A+ + LRA+ + N+ E+++KLA+ +E++
Sbjct: 1528 LEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQ 1587
Query: 263 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQ----QIEEDLEKSEERSGTAQQK--- 421
K ++ L+ T + EV + +K++ ++E L + + AQ++
Sbjct: 1588 AKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKS 1647
Query: 422 ----LLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAED-------ADGK 568
L + Q D+ R L+ E R + L +L+E R + E AD +
Sbjct: 1648 LQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLADRE 1707
Query: 569 SDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXKA 727
E S ++ + + ++ K DA +S L+ E++ ++ E KA
Sbjct: 1708 LIETSERVQLLHSQNTSLINQKKKMDADLSQLQSEVEEAVQECRNAEEKAKKA 1760
Score = 50.4 bits (115), Expect = 7e-06
Identities = 34/134 (25%), Positives = 63/134 (47%), Gaps = 7/134 (5%)
Frame = +2
Query: 326 TEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEER 505
TE E+A + + +I+E LEKSE R ++K++ Q ++ + ++ EER
Sbjct: 847 TEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEER 906
Query: 506 MDQLTN-------QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXL 664
DQL ++KE ED + + E++ K +EDE + + + ++ +
Sbjct: 907 CDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKV 966
Query: 665 EXELKVVGNSLKSL 706
E E N +K+L
Sbjct: 967 EKEKHATENKVKNL 980
Score = 48.8 bits (111), Expect = 2e-05
Identities = 52/218 (23%), Positives = 93/218 (42%), Gaps = 4/218 (1%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLA--- 238
+++ +A+ +Q+ + + D ++ + + + K N EV + + K
Sbjct: 1322 EEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQCRTKYETDA 1381
Query: 239 -QVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQ 415
Q E+L K KL Q +D EE + + A + + ++Q EDL ERS A
Sbjct: 1382 IQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAA 1441
Query: 416 QKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLA 595
L + Q++ D K+L Q+ EE +L + KEAR L+ + + L
Sbjct: 1442 AALDKKQRNFD------KILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESL- 1494
Query: 596 FVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLE 709
+ LE + K+ +IS L +L G ++ LE
Sbjct: 1495 ---EHLETFKRENKNLQEEISDLTEQLGEGGKNVHELE 1529
Score = 48.0 bits (109), Expect = 3e-05
Identities = 32/153 (20%), Positives = 73/153 (47%)
Frame = +2
Query: 164 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 343
QQA D +L+AE+ ++V L K ++E+ + + LEQ K + E+ E ++
Sbjct: 1006 QQALD-DLQAEE--DKVNTLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLK 1062
Query: 344 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 523
+ +E D + EE+ + + + ++ + L+ + ++++ R+++L
Sbjct: 1063 LTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQVLALQLQKKLKENQARIEELEE 1122
Query: 524 QLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 622
+L+ R + ++SR+L + + LE A
Sbjct: 1123 ELEAERTARAKVEKLRSDLSRELEEISERLEEA 1155
Score = 46.4 bits (105), Expect = 1e-04
Identities = 41/226 (18%), Positives = 94/226 (41%), Gaps = 11/226 (4%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQA-MKLEKDNAMDKADTCEQ----------QARDANLRAEKVNEEV 214
++K ++ K +Q ++ E+DN D + C+Q + ++ N R E E
Sbjct: 876 EEKMVSLLQEKNDLQLQVQAEQDNLNDAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMN 935
Query: 215 RELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSE 394
EL K ++E++ K ++ L + EK+ ATE +V L ++ ++E + K
Sbjct: 936 AELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLT 995
Query: 395 ERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSD 574
+ Q+ +A L + E+++D L L++ + + D +
Sbjct: 996 KEKKALQEAHQQALDDLQAEEDKVNTLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKR 1055
Query: 575 EVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEV 712
++ L ++ + E+ + K+ E ++ + ++ +V
Sbjct: 1056 KLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQV 1101
Score = 35.5 bits (78), Expect = 0.20
Identities = 45/214 (21%), Positives = 98/214 (45%), Gaps = 15/214 (7%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNA--MDKADTCEQQARDANLRAEKVNEEV-RELQKKLA 238
QQ + D +Q K K+N +++ + + R A + EK+ ++ REL++
Sbjct: 1091 QQNSKIEDEQVLALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSDLSRELEEISE 1150
Query: 239 QVEE-------DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRK----VQQIEEDLE 385
++EE + +NK + + K + E+ EA AAL +K V ++ E ++
Sbjct: 1151 RLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQID 1210
Query: 386 KSEERSGTAQQKLLEAQQSADE-NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDAD 562
+ +++ E + D+ + M ++++ +A E+ L +Q E R+ E+A
Sbjct: 1211 NLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANL-EKVSRTLEDQANEYRVKLEEAQ 1269
Query: 563 GKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXL 664
++ + + A ++ E +++ +A IS L
Sbjct: 1270 RSLNDFTTQRAKLQTENGELSRQLEEKEALISQL 1303
>Z29064-1|CAA82305.1| 896|Homo sapiens AF-1p protein.
Length = 896
Score = 56.8 bits (131), Expect = 7e-08
Identities = 29/161 (18%), Positives = 80/161 (49%)
Frame = +2
Query: 194 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIE 373
+ +N E+ +LQ++ VE+DL ++ ++Q ++++ + ++ + L + QQ++
Sbjct: 336 DTLNNEIVDLQREKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQ 395
Query: 374 EDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAE 553
E L++ +E+ +++L E ++ E ++ L+ E ++ +L +AR
Sbjct: 396 ELLDELDEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELS 455
Query: 554 DADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXEL 676
++ E+ + + +LE + ++ +IS ++ +L
Sbjct: 456 RLQQETAELEESVESGKAQLEPLQQHLQDSQQEISSMQMKL 496
>Z20656-1|CAA79675.1| 1939|Homo sapiens cardiac alpha-myosin heavy
chain protein.
Length = 1939
Score = 56.8 bits (131), Expect = 7e-08
Identities = 59/233 (25%), Positives = 107/233 (45%), Gaps = 18/233 (7%)
Frame = +2
Query: 86 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVN----EEVRELQKKLAQVEE- 250
+ +K+K++ K E +D + +Q A EKV+ ++ E + KL + +
Sbjct: 1212 LQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRS 1271
Query: 251 --DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNR---KVQQIEEDLEKSEERSGTAQ 415
D + KL+ N +L +QL EA ++ L R Q EDL++ E G A+
Sbjct: 1272 LNDFTTQRAKLQTENGELA---RQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAK 1328
Query: 416 QKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL-LAE-------DADGKS 571
L A QSA + C +L + +++ E +L L +A +A+ DA ++
Sbjct: 1329 NALAHALQSARHD---CDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRT 1385
Query: 572 DEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXKAN 730
+E+ + L+ AE+ V++ +AK S LE + N ++ L V ++N
Sbjct: 1386 EELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSN 1438
Score = 52.4 bits (120), Expect = 2e-06
Identities = 51/218 (23%), Positives = 105/218 (48%), Gaps = 10/218 (4%)
Frame = +2
Query: 86 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAE-KVNEEVRELQKKLAQVEEDLIL 262
++ ++K+++ KLE +A+++A+ + LRA+ + N+ E+++KLA+ +E++
Sbjct: 1528 LEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQ 1587
Query: 263 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 442
K ++ L+ T + EV + +K +E DL + E + A + EAQ+
Sbjct: 1588 AKRNHQRVVDSLQTSLDAETRSRNEVLRVKKK---MEGDLNEMEIQLSHANRMAAEAQKQ 1644
Query: 443 ADENNRMCK----VLENRAQQDEERMDQLT-----NQLKEARLLAEDADGKSDEVSRKLA 595
+ K L++ + +++ + + N L +A L A + E SRKLA
Sbjct: 1645 VKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLA 1704
Query: 596 FVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLE 709
E EL +RV+ ++ + L + K + + L L+
Sbjct: 1705 --EQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQ 1740
Score = 52.0 bits (119), Expect = 2e-06
Identities = 45/202 (22%), Positives = 86/202 (42%), Gaps = 12/202 (5%)
Frame = +2
Query: 161 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 340
+ + D + E+ N L KK ++ L K K E++ +LE +K+ + E+
Sbjct: 1424 QNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTEL 1483
Query: 341 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 520
L ++ E LE + + Q+++ + + E + LE +Q E +L
Sbjct: 1484 FKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQ 1543
Query: 521 NQLKEARLLAEDADGK-----------SDEVSRKLAFVEDELEVAE-DRVKSGDAKISXL 664
+ L+EA E +GK E+ RKLA ++E+E A+ + + D+ + L
Sbjct: 1544 SALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSL 1603
Query: 665 EXELKVVGNSLKSLEVSEXKAN 730
+ E + L+ + E N
Sbjct: 1604 DAETRSRNEVLRVKKKMEGDLN 1625
Score = 50.4 bits (115), Expect = 7e-06
Identities = 34/134 (25%), Positives = 63/134 (47%), Gaps = 7/134 (5%)
Frame = +2
Query: 326 TEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEER 505
TE E+A + + +I+E LEKSE R ++K++ Q ++ + ++ EER
Sbjct: 847 TEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEER 906
Query: 506 MDQLTN-------QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXL 664
DQL ++KE ED + + E++ K +EDE + + + ++ +
Sbjct: 907 CDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKV 966
Query: 665 EXELKVVGNSLKSL 706
E E N +K+L
Sbjct: 967 EKEKHATENKVKNL 980
Score = 48.8 bits (111), Expect = 2e-05
Identities = 47/212 (22%), Positives = 104/212 (49%), Gaps = 8/212 (3%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQA-MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQV 244
++K ++ K +Q ++ E+DN D + C+Q ++ ++ E +E+ E + ++
Sbjct: 876 EEKMVSLLQEKNDLQLQVQAEQDNLNDAEERCDQLIKN-KIQLEAKVKEMNERLEDEEEM 934
Query: 245 EEDLILNKNKLE----QANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEE--RSG 406
+L K KLE + KD+++ E L E E A KV+ + E++ +E
Sbjct: 935 NAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKL 994
Query: 407 TAQQKLL-EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVS 583
T ++K L EA Q A ++ ++ + N + + +++Q + L+ + L ++ + D +
Sbjct: 995 TKEKKALQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGS--LEQEKKVRMD-LE 1051
Query: 584 RKLAFVEDELEVAEDRVKSGDAKISXLEXELK 679
R +E +L++ ++ + + LE +LK
Sbjct: 1052 RAKRKLEGDLKLTQESIMDLENDKLQLEEKLK 1083
Score = 48.8 bits (111), Expect = 2e-05
Identities = 38/188 (20%), Positives = 85/188 (45%), Gaps = 3/188 (1%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMK-LEKDNA-MDKADTCEQQARDANLRAEKVNEE-VRELQKKLA 238
++K AT + +K + M L++ A + K Q+A L +V E+ V L K
Sbjct: 968 KEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVEEDKVNSLSKSKV 1027
Query: 239 QVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQ 418
++E+ + + LEQ K + E+ E ++ + +E D + EE+ +
Sbjct: 1028 KLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEF 1087
Query: 419 KLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAF 598
+ + ++ + L+ + ++++ R+++L +L+ R + ++SR+L
Sbjct: 1088 DINQQNSKIEDEQALALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSDLSRELEE 1147
Query: 599 VEDELEVA 622
+ + LE A
Sbjct: 1148 ISERLEEA 1155
Score = 48.4 bits (110), Expect = 3e-05
Identities = 52/218 (23%), Positives = 93/218 (42%), Gaps = 4/218 (1%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLA--- 238
+++ +A+ +Q+ + + D ++ + + + K N EV + + K
Sbjct: 1322 EEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDA 1381
Query: 239 -QVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQ 415
Q E+L K KL Q +D EE + + A + + ++Q EDL ERS A
Sbjct: 1382 IQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAA 1441
Query: 416 QKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLA 595
L + Q++ D K+L Q+ EE +L + KEAR L+ + + L
Sbjct: 1442 AALDKKQRNFD------KILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESL- 1494
Query: 596 FVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLE 709
+ LE + K+ +IS L +L G ++ LE
Sbjct: 1495 ---EHLETFKRENKNLQEEISDLTEQLGEGGKNVHELE 1529
Score = 43.2 bits (97), Expect = 0.001
Identities = 51/212 (24%), Positives = 93/212 (43%), Gaps = 10/212 (4%)
Frame = +2
Query: 95 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 274
IK +++ + EK+ A K + + ++ ++E +E+ E L Q + DL L
Sbjct: 838 IKPLLKSAETEKEMATMKEEF--GRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQA 895
Query: 275 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 454
+ D EE+ QL + ++ A KV+++ E LE EE + K + + E
Sbjct: 896 EQDNLNDAEERCDQLIKNKIQLEA---KVKEMNERLEDEEEMNAELTAKKRKLEDECSEL 952
Query: 455 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSR----KLAFVE------ 604
+ LE + E+ N++K L E+ G + +++ K A E
Sbjct: 953 KKDIDDLELTLAKVEKEKHATENKVKN---LTEEMAGLDEIIAKLTKEKKALQEAHQQAL 1009
Query: 605 DELEVAEDRVKSGDAKISXLEXELKVVGNSLK 700
D+L+V ED+V S LE ++ + SL+
Sbjct: 1010 DDLQVEEDKVNSLSKSKVKLEQQVDDLEGSLE 1041
Score = 41.5 bits (93), Expect = 0.003
Identities = 47/211 (22%), Positives = 99/211 (46%), Gaps = 18/211 (8%)
Frame = +2
Query: 98 KKKMQA-MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLI-LNK- 268
+++M A + +K D+ ++ D L KV +E + K+ + E++ L++
Sbjct: 931 EEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEI 990
Query: 269 -NKLEQANKDLEEKEKQ----LTATEAEVAALNR---KVQQIEEDLEKSEERSGTAQQKL 424
KL + K L+E +Q L E +V +L++ K++Q +DLE S E+ + L
Sbjct: 991 IAKLTKEKKALQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDL 1050
Query: 425 LEAQQSADENNRMCKV----LENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKL 592
A++ + + ++ + LEN Q EE++ + + + ED + ++ +KL
Sbjct: 1051 ERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQALALQLQKKL 1110
Query: 593 AFVEDELEVAEDRV---KSGDAKISXLEXEL 676
+ +E E+ + ++ AK+ L +L
Sbjct: 1111 KENQARIEELEEELEAERTARAKVEKLRSDL 1141
Score = 35.5 bits (78), Expect = 0.20
Identities = 45/214 (21%), Positives = 98/214 (45%), Gaps = 15/214 (7%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNA--MDKADTCEQQARDANLRAEKVNEEV-RELQKKLA 238
QQ + D +Q K K+N +++ + + R A + EK+ ++ REL++
Sbjct: 1091 QQNSKIEDEQALALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSDLSRELEEISE 1150
Query: 239 QVEE-------DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRK----VQQIEEDLE 385
++EE + +NK + + K + E+ EA AAL +K V ++ E ++
Sbjct: 1151 RLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQID 1210
Query: 386 KSEERSGTAQQKLLEAQQSADE-NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDAD 562
+ +++ E + D+ + M ++++ +A E+ L +Q E R+ E+A
Sbjct: 1211 NLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANL-EKVSRTLEDQANEYRVKLEEAQ 1269
Query: 563 GKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXL 664
++ + + A ++ E +++ +A IS L
Sbjct: 1270 RSLNDFTTQRAKLQTENGELARQLEEKEALISQL 1303
>U07707-1|AAA52101.1| 896|Homo sapiens epidermal growth factor
receptor substrate protein.
Length = 896
Score = 56.8 bits (131), Expect = 7e-08
Identities = 29/161 (18%), Positives = 80/161 (49%)
Frame = +2
Query: 194 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIE 373
+ +N E+ +LQ++ VE+DL ++ ++Q ++++ + ++ + L + QQ++
Sbjct: 336 DTLNNEIVDLQREKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQ 395
Query: 374 EDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAE 553
E L++ +E+ +++L E ++ E ++ L+ E ++ +L +AR
Sbjct: 396 ELLDELDEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELS 455
Query: 554 DADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXEL 676
++ E+ + + +LE + ++ +IS ++ +L
Sbjct: 456 RLQQETAELEESVESGKAQLEPLQQHLQDSQQEISSMQMKL 496
>DQ367924-1|ABD34786.1| 896|Homo sapiens epidermal growth factor
receptor pathway substrate 15 protein.
Length = 896
Score = 56.8 bits (131), Expect = 7e-08
Identities = 29/161 (18%), Positives = 80/161 (49%)
Frame = +2
Query: 194 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIE 373
+ +N E+ +LQ++ VE+DL ++ ++Q ++++ + ++ + L + QQ++
Sbjct: 336 DTLNNEIVDLQREKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQ 395
Query: 374 EDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAE 553
E L++ +E+ +++L E ++ E ++ L+ E ++ +L +AR
Sbjct: 396 ELLDELDEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELS 455
Query: 554 DADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXEL 676
++ E+ + + +LE + ++ +IS ++ +L
Sbjct: 456 RLQQETAELEESVESGKAQLEPLQQHLQDSQQEISSMQMKL 496
>BC132667-1|AAI32668.1| 1939|Homo sapiens myosin, heavy chain 6,
cardiac muscle, alpha (cardiomyopathy, hypertrophic 1)
protein.
Length = 1939
Score = 56.8 bits (131), Expect = 7e-08
Identities = 59/233 (25%), Positives = 107/233 (45%), Gaps = 18/233 (7%)
Frame = +2
Query: 86 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVN----EEVRELQKKLAQVEE- 250
+ +K+K++ K E +D + +Q A EKV+ ++ E + KL + +
Sbjct: 1212 LQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRS 1271
Query: 251 --DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNR---KVQQIEEDLEKSEERSGTAQ 415
D + KL+ N +L +QL EA ++ L R Q EDL++ E G A+
Sbjct: 1272 LNDFTTQRAKLQTENGELA---RQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAK 1328
Query: 416 QKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL-LAE-------DADGKS 571
L A QSA + C +L + +++ E +L L +A +A+ DA ++
Sbjct: 1329 NALAHALQSARHD---CDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRT 1385
Query: 572 DEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXKAN 730
+E+ + L+ AE+ V++ +AK S LE + N ++ L V ++N
Sbjct: 1386 EELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSN 1438
Score = 52.4 bits (120), Expect = 2e-06
Identities = 51/218 (23%), Positives = 105/218 (48%), Gaps = 10/218 (4%)
Frame = +2
Query: 86 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAE-KVNEEVRELQKKLAQVEEDLIL 262
++ ++K+++ KLE +A+++A+ + LRA+ + N+ E+++KLA+ +E++
Sbjct: 1528 LEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQ 1587
Query: 263 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 442
K ++ L+ T + EV + +K +E DL + E + A + EAQ+
Sbjct: 1588 AKRNHQRVVDSLQTSLDAETRSRNEVLRVKKK---MEGDLNEMEIQLSHANRMAAEAQKQ 1644
Query: 443 ADENNRMCK----VLENRAQQDEERMDQLT-----NQLKEARLLAEDADGKSDEVSRKLA 595
+ K L++ + +++ + + N L +A L A + E SRKLA
Sbjct: 1645 VKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLA 1704
Query: 596 FVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLE 709
E EL +RV+ ++ + L + K + + L L+
Sbjct: 1705 --EQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQ 1740
Score = 52.0 bits (119), Expect = 2e-06
Identities = 45/202 (22%), Positives = 86/202 (42%), Gaps = 12/202 (5%)
Frame = +2
Query: 161 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 340
+ + D + E+ N L KK ++ L K K E++ +LE +K+ + E+
Sbjct: 1424 QNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTEL 1483
Query: 341 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 520
L ++ E LE + + Q+++ + + E + LE +Q E +L
Sbjct: 1484 FKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQ 1543
Query: 521 NQLKEARLLAEDADGK-----------SDEVSRKLAFVEDELEVAE-DRVKSGDAKISXL 664
+ L+EA E +GK E+ RKLA ++E+E A+ + + D+ + L
Sbjct: 1544 SALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSL 1603
Query: 665 EXELKVVGNSLKSLEVSEXKAN 730
+ E + L+ + E N
Sbjct: 1604 DAETRSRNEVLRVKKKMEGDLN 1625
Score = 50.4 bits (115), Expect = 7e-06
Identities = 34/134 (25%), Positives = 63/134 (47%), Gaps = 7/134 (5%)
Frame = +2
Query: 326 TEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEER 505
TE E+A + + +I+E LEKSE R ++K++ Q ++ + ++ EER
Sbjct: 847 TEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEER 906
Query: 506 MDQLTN-------QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXL 664
DQL ++KE ED + + E++ K +EDE + + + ++ +
Sbjct: 907 CDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKV 966
Query: 665 EXELKVVGNSLKSL 706
E E N +K+L
Sbjct: 967 EKEKHATENKVKNL 980
Score = 48.4 bits (110), Expect = 3e-05
Identities = 52/218 (23%), Positives = 93/218 (42%), Gaps = 4/218 (1%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLA--- 238
+++ +A+ +Q+ + + D ++ + + + K N EV + + K
Sbjct: 1322 EEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDA 1381
Query: 239 -QVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQ 415
Q E+L K KL Q +D EE + + A + + ++Q EDL ERS A
Sbjct: 1382 IQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAA 1441
Query: 416 QKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLA 595
L + Q++ D K+L Q+ EE +L + KEAR L+ + + L
Sbjct: 1442 AALDKKQRNFD------KILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESL- 1494
Query: 596 FVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLE 709
+ LE + K+ +IS L +L G ++ LE
Sbjct: 1495 ---EHLETFKRENKNLQEEISDLTEQLGEGGKNVHELE 1529
Score = 48.0 bits (109), Expect = 3e-05
Identities = 38/188 (20%), Positives = 85/188 (45%), Gaps = 3/188 (1%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMK-LEKDNA-MDKADTCEQQARDANLRAEKVNEE-VRELQKKLA 238
++K AT + +K + M L++ A + K Q+A L +V E+ V L K
Sbjct: 968 KEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVEEDKVNSLSKSKV 1027
Query: 239 QVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQ 418
++E+ + + LEQ K + E+ E ++ + +E D + EE+ +
Sbjct: 1028 KLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEF 1087
Query: 419 KLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAF 598
+ + ++ + L+ + ++++ R+++L +L+ R + ++SR+L
Sbjct: 1088 DINQQNSKIEDEQVLALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSDLSRELEE 1147
Query: 599 VEDELEVA 622
+ + LE A
Sbjct: 1148 ISERLEEA 1155
Score = 45.2 bits (102), Expect = 2e-04
Identities = 41/226 (18%), Positives = 94/226 (41%), Gaps = 11/226 (4%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQA-MKLEKDNAMDKADTCEQ----------QARDANLRAEKVNEEV 214
++K ++ K +Q ++ E+DN D + C+Q + ++ N R E E
Sbjct: 876 EEKMVSLLQEKNDLQLQVQAEQDNLNDAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMN 935
Query: 215 RELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSE 394
EL K ++E++ K ++ L + EK+ ATE +V L ++ ++E + K
Sbjct: 936 AELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLT 995
Query: 395 ERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSD 574
+ Q+ +A L + E+++D L L++ + + D +
Sbjct: 996 KEKKALQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKR 1055
Query: 575 EVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEV 712
++ L ++ + E+ + K+ E ++ + ++ +V
Sbjct: 1056 KLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQV 1101
Score = 35.1 bits (77), Expect = 0.26
Identities = 45/214 (21%), Positives = 98/214 (45%), Gaps = 15/214 (7%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNA--MDKADTCEQQARDANLRAEKVNEEV-RELQKKLA 238
QQ + D +Q K K+N +++ + + R A + EK+ ++ REL++
Sbjct: 1091 QQNSKIEDEQVLALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSDLSRELEEISE 1150
Query: 239 QVEE-------DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRK----VQQIEEDLE 385
++EE + +NK + + K + E+ EA AAL +K V ++ E ++
Sbjct: 1151 RLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQID 1210
Query: 386 KSEERSGTAQQKLLEAQQSADE-NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDAD 562
+ +++ E + D+ + M ++++ +A E+ L +Q E R+ E+A
Sbjct: 1211 NLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANL-EKVSRTLEDQANEYRVKLEEAQ 1269
Query: 563 GKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXL 664
++ + + A ++ E +++ +A IS L
Sbjct: 1270 RSLNDFTTQRAKLQTENGELARQLEEKEALISQL 1303
>AL671986-11|CAI13030.1| 896|Homo sapiens epidermal growth factor
receptor pathway substrate 15 protein.
Length = 896
Score = 56.8 bits (131), Expect = 7e-08
Identities = 29/161 (18%), Positives = 80/161 (49%)
Frame = +2
Query: 194 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIE 373
+ +N E+ +LQ++ VE+DL ++ ++Q ++++ + ++ + L + QQ++
Sbjct: 336 DTLNNEIVDLQREKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQ 395
Query: 374 EDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAE 553
E L++ +E+ +++L E ++ E ++ L+ E ++ +L +AR
Sbjct: 396 ELLDELDEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELS 455
Query: 554 DADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXEL 676
++ E+ + + +LE + ++ +IS ++ +L
Sbjct: 456 RLQQETAELEESVESGKAQLEPLQQHLQDSQQEISSMQMKL 496
>AK093463-1|BAC04173.1| 650|Homo sapiens protein ( Homo sapiens
cDNA FLJ36144 fis, clone TESTI2025022, weakly similar to
TRICHOHYALIN. ).
Length = 650
Score = 56.8 bits (131), Expect = 7e-08
Identities = 39/174 (22%), Positives = 91/174 (52%), Gaps = 1/174 (0%)
Frame = +2
Query: 161 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 340
E++ R+ + + E++ +K+L + E++L + +L + K L E+E+Q+ E ++
Sbjct: 299 EERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKK-LREQEEQMQEQEEKM 357
Query: 341 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA-DENNRMCKVLENRAQQDEERMDQL 517
K+++ EE + + EER ++++ E +Q D+ RM + + R ++ EERM +
Sbjct: 358 WEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQ-DERLREKEERMREQ 416
Query: 518 TNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELK 679
++ + E+ K E +K E++++ E+R++ + K+ E ++
Sbjct: 417 EKMWEQVEKMREEK--KMQEQEKKTRDQEEKMQ-EEERIREREKKMREEEETMR 467
Score = 52.4 bits (120), Expect = 2e-06
Identities = 42/190 (22%), Positives = 97/190 (51%), Gaps = 2/190 (1%)
Frame = +2
Query: 95 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVREL-QKKLAQVEEDLILNKN 271
++++ Q M+ +++ M + D ++ + EK+ E+V ++ ++K Q +E ++
Sbjct: 385 MREQEQKMR-DQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQE 443
Query: 272 KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADE 451
+ Q + + E+EK++ E + K+Q+ EE++ + EE+ QQ+L E ++ E
Sbjct: 444 EKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKE-WQQQRLPEQKEKLWE 502
Query: 452 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSR-KLAFVEDELEVAED 628
+M + E +Q+E+ DQ +E ++ E+ +E+ R K + D+ E ++
Sbjct: 503 QEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWQEEKMWGQEEMMREKEERIRDQKEKMQE 562
Query: 629 RVKSGDAKIS 658
R+ + + S
Sbjct: 563 RLPEHEERCS 572
Score = 47.6 bits (108), Expect = 5e-05
Identities = 39/182 (21%), Positives = 86/182 (47%), Gaps = 4/182 (2%)
Frame = +2
Query: 98 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKV----NEEVRELQKKLAQVEEDLILN 265
K + Q K+ + + E + ++ LR +K E+++E ++K+ + EE +
Sbjct: 308 KMREQEEKMWRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQ 367
Query: 266 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 445
+ K+ + + L E+EKQ+ E ++ ++ + +E L + EER Q+K+ E +
Sbjct: 368 EEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERM-REQEKMWEQVEKM 426
Query: 446 DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAE 625
E +M + E + + EE+M Q +++E + + E K+ E+ + E
Sbjct: 427 REEKKM-QEQEKKTRDQEEKM-QEEERIREREKKMREEEETMREQEEKMQKQEENMWEQE 484
Query: 626 DR 631
++
Sbjct: 485 EK 486
Score = 46.4 bits (105), Expect = 1e-04
Identities = 31/206 (15%), Positives = 98/206 (47%), Gaps = 2/206 (0%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNA--MDKADTCEQQARDANLRAEKVNEEVRELQKKLAQ 241
++ A +++ + + +L+K NA +K E + + L +++ ++ + L Q
Sbjct: 205 ERDALSLELYRNTITNEELKKKNAELQEKLPLAESEKSEIQLNVKELKRKLERAKFLLPQ 264
Query: 242 VEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQK 421
V+ + + + ++ + ++L E+EK++ E ++ ++++ E + + EE+ +++
Sbjct: 265 VQTNTL--QEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKR 322
Query: 422 LLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFV 601
L E ++ E + + + + ++ EE+M + ++ E + + K +L
Sbjct: 323 LREQEKELREQEKELRE-QKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQ 381
Query: 602 EDELEVAEDRVKSGDAKISXLEXELK 679
E ++ E +++ + ++ + L+
Sbjct: 382 EKQMREQEQKMRDQEERMWEQDERLR 407
>BC112391-1|AAI12392.1| 957|Homo sapiens ELKS/RAB6-interacting/CAST
family member 2 protein.
Length = 957
Score = 56.4 bits (130), Expect = 1e-07
Identities = 49/224 (21%), Positives = 103/224 (45%), Gaps = 3/224 (1%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
+Q+AA + ++ EK++ ++K +Q +D + E+R+++ L E
Sbjct: 482 EQRAAILQTEVDALRLRLEEKESFLNKKT---KQLQDLTEEKGTLAGEIRDMKDMLEVKE 538
Query: 248 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 427
+ + + K+E + L +K+KQLT L +V+ ++ D ++ T ++ L
Sbjct: 539 RKINVLQKKIENLQEQLRDKDKQLT-------NLKDRVKSLQTDSSNTDTALATLEEALS 591
Query: 428 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 607
E ++ + ++ E R + D ER++++ + KE + L E + E++ K + + D
Sbjct: 592 EKERIIE------RLKEQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESSLID 645
Query: 608 ELEVAEDRVKSG---DAKISXLEXELKVVGNSLKSLEVSEXKAN 730
E A +G D+K+ LE ++ LE KA+
Sbjct: 646 LKEHASSLASAGLKRDSKLKSLEIAIEQKKEECSKLEAQLKKAH 689
Score = 39.1 bits (87), Expect = 0.016
Identities = 49/211 (23%), Positives = 93/211 (44%), Gaps = 11/211 (5%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEE-VRELQKKLAQV 244
+ K + +K ++++++ + N T E+ + E++ E+ R+ +++L ++
Sbjct: 556 RDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRERLEEI 615
Query: 245 EEDLILNKNKLEQANK---DLEEKEKQLT-----ATEAEVAALNR--KVQQIEEDLEKSE 394
E NK+ E+ N +L EKE L A+ A L R K++ +E +E+ +
Sbjct: 616 ESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKK 675
Query: 395 ERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSD 574
E LEAQ N +E+ ++ + E DQ+ KEA ++
Sbjct: 676 EECSK-----LEAQLKKAHN------IEDDSRMNPEFADQIKQLDKEASYYRDECGKAQA 724
Query: 575 EVSRKLAFVEDELEVAEDRVKSGDAKISXLE 667
EV R L +++ E+ D KI+ LE
Sbjct: 725 EVDRLLEILKE----VENEKNDKDKKIAELE 751
Score = 31.1 bits (67), Expect = 4.3
Identities = 22/110 (20%), Positives = 51/110 (46%), Gaps = 1/110 (0%)
Frame = +2
Query: 212 VRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKS 391
+++ KK+A ++ + L K K Q +++ +E + + +++++ LEK+
Sbjct: 758 MKDQNKKVANLKHNQQLEKKKNAQLLEEVRRREDSMADNSQHL-----QIEELMNALEKT 812
Query: 392 EERSGTAQQKLLEAQQS-ADENNRMCKVLENRAQQDEERMDQLTNQLKEA 538
+ + +L QQS A++ + + R +Q EE ++ L A
Sbjct: 813 RQELDATKARLASTQQSLAEKEAHLANLRIERRKQLEEILEMKQEALLAA 862
>BC111550-1|AAI11551.1| 957|Homo sapiens ERC2 protein protein.
Length = 957
Score = 56.4 bits (130), Expect = 1e-07
Identities = 49/224 (21%), Positives = 103/224 (45%), Gaps = 3/224 (1%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
+Q+AA + ++ EK++ ++K +Q +D + E+R+++ L E
Sbjct: 482 EQRAAILQTEVDALRLRLEEKESFLNKKT---KQLQDLTEEKGTLAGEIRDMKDMLEVKE 538
Query: 248 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 427
+ + + K+E + L +K+KQLT L +V+ ++ D ++ T ++ L
Sbjct: 539 RKINVLQKKIENLQEQLRDKDKQLT-------NLKDRVKSLQTDSSNTDTALATLEEALS 591
Query: 428 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 607
E ++ + ++ E R + D ER++++ + KE + L E + E++ K + + D
Sbjct: 592 EKERIIE------RLKEQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESSLID 645
Query: 608 ELEVAEDRVKSG---DAKISXLEXELKVVGNSLKSLEVSEXKAN 730
E A +G D+K+ LE ++ LE KA+
Sbjct: 646 LKEHASSLASAGLKRDSKLKSLEIAIEQKKEECSKLEAQLKKAH 689
Score = 39.1 bits (87), Expect = 0.016
Identities = 49/211 (23%), Positives = 93/211 (44%), Gaps = 11/211 (5%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEE-VRELQKKLAQV 244
+ K + +K ++++++ + N T E+ + E++ E+ R+ +++L ++
Sbjct: 556 RDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRERLEEI 615
Query: 245 EEDLILNKNKLEQANK---DLEEKEKQLT-----ATEAEVAALNR--KVQQIEEDLEKSE 394
E NK+ E+ N +L EKE L A+ A L R K++ +E +E+ +
Sbjct: 616 ESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKK 675
Query: 395 ERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSD 574
E LEAQ N +E+ ++ + E DQ+ KEA ++
Sbjct: 676 EECSK-----LEAQLKKAHN------IEDDSRMNPEFADQIKQLDKEASYYRDECGKAQA 724
Query: 575 EVSRKLAFVEDELEVAEDRVKSGDAKISXLE 667
EV R L +++ E+ D KI+ LE
Sbjct: 725 EVDRLLEILKE----VENEKNDKDKKIAELE 751
Score = 31.1 bits (67), Expect = 4.3
Identities = 22/110 (20%), Positives = 51/110 (46%), Gaps = 1/110 (0%)
Frame = +2
Query: 212 VRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKS 391
+++ KK+A ++ + L K K Q +++ +E + + +++++ LEK+
Sbjct: 758 MKDQNKKVANLKHNQQLEKKKNAQLLEEVRRREDSMADNSQHL-----QIEELMNALEKT 812
Query: 392 EERSGTAQQKLLEAQQS-ADENNRMCKVLENRAQQDEERMDQLTNQLKEA 538
+ + +L QQS A++ + + R +Q EE ++ L A
Sbjct: 813 RQELDATKARLASTQQSLAEKEAHLANLRIERRKQLEEILEMKQEALLAA 862
>AK092490-1|BAC03904.1| 280|Homo sapiens protein ( Homo sapiens
cDNA FLJ35171 fis, clone PLACE6013220, weakly similar to
TRICHOHYALIN. ).
Length = 280
Score = 56.4 bits (130), Expect = 1e-07
Identities = 36/162 (22%), Positives = 78/162 (48%)
Frame = +2
Query: 182 NLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKV 361
+L + E +RE +++L + EE +++L + + L E+E++L E + ++
Sbjct: 3 SLLNRRQEERLREQEERLREQEERQREQEDRLHEQEERLREQEERLCEQEERLCEQEERL 62
Query: 362 QQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEAR 541
++ EE L + EER +++L E ++ E + E R + EER+ + +L E
Sbjct: 63 REHEERLCEQEERLCEQEERLREQEERLHEQEERLREQEERLCEQEERLREHEERLCEQE 122
Query: 542 LLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLE 667
+ + + E +L E+ L E+R++ + ++ E
Sbjct: 123 ERLREQEERLCEQEERLREQEERLCEQEERLREQEERLCEQE 164
Score = 56.4 bits (130), Expect = 1e-07
Identities = 32/126 (25%), Positives = 68/126 (53%), Gaps = 1/126 (0%)
Frame = +2
Query: 161 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 340
E++ R+ R + + + E +++L + EE L + +L + + L E E++L E +
Sbjct: 17 EERLREQEERQREQEDRLHEQEERLREQEERLCEQEERLCEQEERLREHEERLCEQEERL 76
Query: 341 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENN-RMCKVLENRAQQDEERMDQL 517
++++ EE L + EER +++L E ++ E+ R+C+ E R ++ EER+ +
Sbjct: 77 CEQEERLREQEERLHEQEERLREQEERLCEQEERLREHEERLCEQ-EERLREQEERLCEQ 135
Query: 518 TNQLKE 535
+L+E
Sbjct: 136 EERLRE 141
Score = 56.0 bits (129), Expect = 1e-07
Identities = 35/159 (22%), Positives = 83/159 (52%), Gaps = 4/159 (2%)
Frame = +2
Query: 89 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKV---NEEVRELQKKLAQVEEDLI 259
+ ++++ + + ++D ++ + +Q + E++ E +RE +++L + EE L
Sbjct: 18 ERLREQEERQREQEDRLHEQEERLREQEERLCEQEERLCEQEERLREHEERLCEQEERLC 77
Query: 260 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 439
+ +L + + L E+E++L E + ++++ EE L + EER +++L E ++
Sbjct: 78 EQEERLREQEERLHEQEERLREQEERLCEQEERLREHEERLCEQEERLREQEERLCEQEE 137
Query: 440 SA-DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAE 553
++ R+C+ E R ++ EER+ + + RLL E
Sbjct: 138 RLREQEERLCEQ-EERLREQEERLCEQEKLPGQERLLEE 175
Score = 53.2 bits (122), Expect = 9e-07
Identities = 39/158 (24%), Positives = 78/158 (49%)
Frame = +2
Query: 161 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 340
E++ R+ R + E RE + +L + EE L + +L + + L E+E++L E +
Sbjct: 10 EERLREQEERLREQEERQREQEDRLHEQEERLREQEERLCEQEERLCEQEERLREHEERL 69
Query: 341 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 520
++ + EE L + EER +++L E ++ R+C+ E R ++ EER+ +
Sbjct: 70 CEQEERLCEQEERLREQEERLHEQEERLREQEE------RLCE-QEERLREHEERLCEQE 122
Query: 521 NQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRV 634
+L+E + + + E +L E+ L E+R+
Sbjct: 123 ERLREQEERLCEQEERLREQEERLCEQEERLREQEERL 160
Score = 52.0 bits (119), Expect = 2e-06
Identities = 34/154 (22%), Positives = 70/154 (45%)
Frame = +2
Query: 215 RELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSE 394
R +++L + EE L + + + L E+E++L E + ++ + EE L + E
Sbjct: 7 RRQEERLREQEERLREQEERQREQEDRLHEQEERLREQEERLCEQEERLCEQEERLREHE 66
Query: 395 ERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSD 574
ER +++L E ++ E E R ++ EER+ + +L+E + + +
Sbjct: 67 ERLCEQEERLCEQEERLREQEERLHEQEERLREQEERLCEQEERLREHEERLCEQEERLR 126
Query: 575 EVSRKLAFVEDELEVAEDRVKSGDAKISXLEXEL 676
E +L E+ L E+R+ + ++ E L
Sbjct: 127 EQEERLCEQEERLREQEERLCEQEERLREQEERL 160
Score = 46.4 bits (105), Expect = 1e-04
Identities = 32/145 (22%), Positives = 65/145 (44%)
Frame = +2
Query: 245 EEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL 424
EE L + +L + + E+E +L E + ++ + EE L + EER +++L
Sbjct: 10 EERLREQEERLREQEERQREQEDRLHEQEERLREQEERLCEQEERLCEQEERLREHEERL 69
Query: 425 LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVE 604
E ++ E + E R + EER+ + +L E + + + E +L E
Sbjct: 70 CEQEERLCEQEERLREQEERLHEQEERLREQEERLCEQEERLREHEERLCEQEERLREQE 129
Query: 605 DELEVAEDRVKSGDAKISXLEXELK 679
+ L E+R++ + ++ E L+
Sbjct: 130 ERLCEQEERLREQEERLCEQEERLR 154
Score = 46.4 bits (105), Expect = 1e-04
Identities = 35/144 (24%), Positives = 72/144 (50%), Gaps = 12/144 (8%)
Frame = +2
Query: 161 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 340
E++ R+ R + E +RE +++L + EE L ++ +L + + L E+E++L E +
Sbjct: 80 EERLREQEERLHEQEERLREQEERLCEQEERLREHEERLCEQEERLREQEERLCEQEERL 139
Query: 341 AALNRKVQQIEEDLEKSEERSGTAQ------------QKLLEAQQSADENNRMCKVLENR 484
++ + EE L + EER + +KLLE ++ +E R+ + E
Sbjct: 140 REQEERLCEQEERLREQEERLCEQEKLPGQERLLEEVEKLLEQERRQEEQERLLE-RERL 198
Query: 485 AQQDEERMDQLTNQLKEARLLAED 556
++ E+ ++Q Q ++ RLL +
Sbjct: 199 LEEVEKLLEQERQQEEQERLLERE 222
Score = 43.2 bits (97), Expect = 0.001
Identities = 32/117 (27%), Positives = 63/117 (53%), Gaps = 1/117 (0%)
Frame = +2
Query: 158 CEQQARDANLRAEKVNEEVREL-QKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEA 334
CEQ+ E++ EEV +L +++ Q E++ +L + +L + + L E+E+Q E
Sbjct: 161 CEQEKLPGQ---ERLLEEVEKLLEQERRQEEQERLLERERLLEEVEKLLEQERQQEEQE- 216
Query: 335 EVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEER 505
+ R ++++E+ LE +ER Q++LLE ++ DE + +E +Q+ R
Sbjct: 217 RLLERERLLEEVEKLLE--QERRQEEQERLLERERLLDEVEELLDEVEELLEQERLR 271
>AB002376-1|BAA20832.2| 970|Homo sapiens KIAA0378 protein.
Length = 970
Score = 56.4 bits (130), Expect = 1e-07
Identities = 49/224 (21%), Positives = 103/224 (45%), Gaps = 3/224 (1%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
+Q+AA + ++ EK++ ++K +Q +D + E+R+++ L E
Sbjct: 495 EQRAAILQTEVDALRLRLEEKESFLNKKT---KQLQDLTEEKGTLAGEIRDMKDMLEVKE 551
Query: 248 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 427
+ + + K+E + L +K+KQLT L +V+ ++ D ++ T ++ L
Sbjct: 552 RKINVLQKKIENLQEQLRDKDKQLT-------NLKDRVKSLQTDSSNTDTALATLEEALS 604
Query: 428 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 607
E ++ + ++ E R + D ER++++ + KE + L E + E++ K + + D
Sbjct: 605 EKERIIE------RLKEQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESSLID 658
Query: 608 ELEVAEDRVKSG---DAKISXLEXELKVVGNSLKSLEVSEXKAN 730
E A +G D+K+ LE ++ LE KA+
Sbjct: 659 LKEHASSLASAGLKRDSKLKSLEIAIEQKKEECSKLEAQLKKAH 702
Score = 39.1 bits (87), Expect = 0.016
Identities = 49/211 (23%), Positives = 93/211 (44%), Gaps = 11/211 (5%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEE-VRELQKKLAQV 244
+ K + +K ++++++ + N T E+ + E++ E+ R+ +++L ++
Sbjct: 569 RDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRERLEEI 628
Query: 245 EEDLILNKNKLEQANK---DLEEKEKQLT-----ATEAEVAALNR--KVQQIEEDLEKSE 394
E NK+ E+ N +L EKE L A+ A L R K++ +E +E+ +
Sbjct: 629 ESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKK 688
Query: 395 ERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSD 574
E LEAQ N +E+ ++ + E DQ+ KEA ++
Sbjct: 689 EECSK-----LEAQLKKAHN------IEDDSRMNPEFADQIKQLDKEASYYRDECGKAQA 737
Query: 575 EVSRKLAFVEDELEVAEDRVKSGDAKISXLE 667
EV R L +++ E+ D KI+ LE
Sbjct: 738 EVDRLLEILKE----VENEKNDKDKKIAELE 764
Score = 31.1 bits (67), Expect = 4.3
Identities = 22/110 (20%), Positives = 51/110 (46%), Gaps = 1/110 (0%)
Frame = +2
Query: 212 VRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKS 391
+++ KK+A ++ + L K K Q +++ +E + + +++++ LEK+
Sbjct: 771 MKDQNKKVANLKHNQQLEKKKNAQLLEEVRRREDSMADNSQHL-----QIEELMNALEKT 825
Query: 392 EERSGTAQQKLLEAQQS-ADENNRMCKVLENRAQQDEERMDQLTNQLKEA 538
+ + +L QQS A++ + + R +Q EE ++ L A
Sbjct: 826 RQELDATKARLASTQQSLAEKEAHLANLRIERRKQLEEILEMKQEALLAA 875
>AF362887-1|AAK51964.1| 142|Homo sapiens tropomyosin 4-anaplastic
lymphoma kinase fusion protein minor isoform protein.
Length = 142
Score = 56.0 bits (129), Expect = 1e-07
Identities = 30/113 (26%), Positives = 66/113 (58%), Gaps = 3/113 (2%)
Frame = +2
Query: 290 KDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCK 469
+++E + + EAEVA+LNR++Q +EE+L++++ER+ ++ K + ++ K
Sbjct: 1 REVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERAEVSELKCGDLEEELKNVTNNLK 60
Query: 470 VLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVE---DELEV 619
LE +++ E+ D+ ++K ++A+ +++ R +A +E D+LEV
Sbjct: 61 SLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEV 113
Score = 48.4 bits (110), Expect = 3e-05
Identities = 24/67 (35%), Positives = 41/67 (61%)
Frame = +2
Query: 524 QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKS 703
+++ R E A+ + ++R++ VE+EL+ A++R + + K LE ELK V N+LKS
Sbjct: 2 EVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERAEVSELKCGDLEEELKNVTNNLKS 61
Query: 704 LEVSEXK 724
LE + K
Sbjct: 62 LEAASEK 68
>AF200415-1|AAF08305.2| 1825|Homo sapiens proliferation-related
protein P80 protein.
Length = 1825
Score = 56.0 bits (129), Expect = 1e-07
Identities = 56/200 (28%), Positives = 97/200 (48%), Gaps = 4/200 (2%)
Frame = +2
Query: 122 LEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLE 301
LE ++ DT Q +D L + NE V++ K L Q DL LEQ +K LE
Sbjct: 1374 LEHKEVVEPKDTAIYQ-KDEALHVK--NEAVKQQDKALEQKGRDLEQKDTALEQKDKALE 1430
Query: 302 EKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN-NRMCKVLE 478
K+K L E + AL +K +I E+ +K+ E+ TA ++ +A + D++ + +VLE
Sbjct: 1431 PKDKDL---EEKDKALEQK-DKIPEEKDKALEQKDTALEQKDKALEPKDKDLEQKDRVLE 1486
Query: 479 NRAQQDEERMDQLTNQLKEARLLA-ED--ADGKSDEVSRKLAFVEDELEVAEDRVKSGDA 649
+ + EE+ L +++ A ED A+ K ++ + E + + E + K +
Sbjct: 1487 QKEKIPEEKDKALDQKVRSVEHKAPEDTVAEMKDRDLEQTDKAPEQKHQAQEQKDKVSEK 1546
Query: 650 KISXLEXELKVVGNSLKSLE 709
K LE + +G ++LE
Sbjct: 1547 KDQALEQKYWALGQKDEALE 1566
Score = 49.2 bits (112), Expect = 2e-05
Identities = 51/207 (24%), Positives = 101/207 (48%), Gaps = 6/207 (2%)
Frame = +2
Query: 125 EKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEE 304
EKD A+++ D ++ +D L E+ + + + K L ++DL LEQ K EE
Sbjct: 1438 EKDKALEQKDKIPEE-KDKAL--EQKDTALEQKDKALEPKDKDLEQKDRVLEQKEKIPEE 1494
Query: 305 KEKQLTATEAEVAALNRKVQQ--IEEDLEKSEERSGTAQQKLLEAQQSADE-NNRMCKVL 475
K+K A + +V ++ K + + E ++ E++ A ++ +AQ+ D+ + + + L
Sbjct: 1495 KDK---ALDQKVRSVEHKAPEDTVAEMKDRDLEQTDKAPEQKHQAQEQKDKVSEKKDQAL 1551
Query: 476 ENR---AQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGD 646
E + Q +E ++Q L+E E ++ +RK +E E + ++VK+ +
Sbjct: 1552 EQKYWALGQKDEALEQNIQALEENHQTQEQESLVQEDKTRKPKMLE---EKSPEKVKAME 1608
Query: 647 AKISXLEXELKVVGNSLKSLEVSEXKA 727
K+ L + K +G L+ V E +A
Sbjct: 1609 EKLEALLEKTKALG--LEESLVQEGRA 1633
Score = 38.3 bits (85), Expect = 0.028
Identities = 33/149 (22%), Positives = 73/149 (48%)
Frame = +2
Query: 89 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 268
D + ++ + + EKD A+D Q+ R +A + + V E++ + + + K
Sbjct: 1482 DRVLEQKEKIPEEKDKALD------QKVRSVEHKAPE--DTVAEMKDRDLEQTDKAPEQK 1533
Query: 269 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSAD 448
++ ++ + EK+ Q A E + AL +K + +E++++ EE T +Q+ L +
Sbjct: 1534 HQAQEQKDKVSEKKDQ--ALEQKYWALGQKDEALEQNIQALEENHQTQEQESL----VQE 1587
Query: 449 ENNRMCKVLENRAQQDEERMDQLTNQLKE 535
+ R K+LE ++ + + M++ L E
Sbjct: 1588 DKTRKPKMLEEKSPEKVKAMEEKLEALLE 1616
>Z15005-1|CAA78727.1| 2663|Homo sapiens CENP-E protein.
Length = 2663
Score = 55.2 bits (127), Expect = 2e-07
Identities = 44/198 (22%), Positives = 98/198 (49%), Gaps = 8/198 (4%)
Frame = +2
Query: 86 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 265
M + K++Q E + + D ++ ++++ E ++E+ K + EE+L +
Sbjct: 1423 MLGLSKRLQESHDEMKSVAKEKDDLQRLQEVLQSESDQLKENIKEIVAKHLETEEELKVA 1482
Query: 266 ----KNKLEQANK---DLEEKEKQLTATEAEVAALNRKVQ-QIEEDLEKSEERSGTAQQK 421
K + E N+ +L EKE +++ + ++ A+N K+Q +I+E EK E+ + +
Sbjct: 1483 HCCLKEQEETINELRVNLSEKETEISTIQKQLEAINDKLQNKIQEIYEKEEQLNIKQISE 1542
Query: 422 LLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFV 601
+ E + K ++ Q E +M +LTN+L+E++ + + +E+ R V
Sbjct: 1543 VQENVNELKQFKEHRKAKDSALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKR----V 1598
Query: 602 EDELEVAEDRVKSGDAKI 655
++ L++ D++K +I
Sbjct: 1599 QEALQIERDQLKENTKEI 1616
Score = 43.2 bits (97), Expect = 0.001
Identities = 39/185 (21%), Positives = 87/185 (47%), Gaps = 7/185 (3%)
Frame = +2
Query: 143 DKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK---LEQANKDLEEKEK 313
+K QQ ++ + V EE+ E+QKK+ ++E KNK LE + E +
Sbjct: 1127 EKLKEKSQQLQEKQQQLLNVQEEMSEMQKKINEIENLKNELKNKELTLEHMETERLELAQ 1186
Query: 314 QLTATEAEVAALNRKVQQIEEDLEKS-EERSGTAQQKLLEAQQSADENNRMCKVLENRAQ 490
+L EV ++ K +++ ++L+KS E + + E + + + K+ +
Sbjct: 1187 KLNENYEEVKSIT-KERKVLKELQKSFETERDHLRGYIREIEATGLQTKEELKIAHIHLK 1245
Query: 491 QDEERMDQLTNQLKE--ARLL-AEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISX 661
+ +E +D+L + E A+++ +D + ++ ++ + +E E+ + K + + +
Sbjct: 1246 EHQETIDELRRSVSEKTAQIINTQDLEKSHTKLQEEIPVLHEEQELLPNVKKVSETQETM 1305
Query: 662 LEXEL 676
E EL
Sbjct: 1306 NELEL 1310
Score = 42.7 bits (96), Expect = 0.001
Identities = 43/183 (23%), Positives = 88/183 (48%), Gaps = 4/183 (2%)
Frame = +2
Query: 191 AEKVNEEVRELQKKLAQVEEDLILNKNKLEQ----ANKDLEEKEKQLTATEAEVAALNRK 358
+EK NE + +QK L + L K+++ A+ L+E+++ + V+ K
Sbjct: 1745 SEKTNE-ISNMQKDLEHSNDALKAQDLKIQEELRIAHMHLKEQQETIDKLRGIVSEKTDK 1803
Query: 359 VQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEA 538
+ +++DLE S + Q+K+ E + + + + K + N Q+ M+QL Q+K+
Sbjct: 1804 LSNMQKDLENSNAK---LQEKIQELKANEHQLITLKKDV-NETQKKVSEMEQLKKQIKDQ 1859
Query: 539 RLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSE 718
L + ++ ++++L + LE + +K D + +E LK+ + LK + E
Sbjct: 1860 SLTLSKLEIENLNLAQEL---HENLEEMKSVMKERD-NLRRVEETLKLERDQLKE-SLQE 1914
Query: 719 XKA 727
KA
Sbjct: 1915 TKA 1917
Score = 40.7 bits (91), Expect = 0.005
Identities = 26/140 (18%), Positives = 66/140 (47%)
Frame = +2
Query: 161 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 340
+Q E++ +++E + + +E+L L ++L++ + + +++ E E+
Sbjct: 1056 QQMLESVIAEKEQLKTDLKENIEMTIENQEELRLLGDELKKQQEIVAQEKNHAIKKEGEL 1115
Query: 341 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 520
+ ++ ++EE L++ ++ QQ+LL Q+ E + +EN + + + L
Sbjct: 1116 SRTCDRLAEVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQKKINEIENLKNELKNKELTLE 1175
Query: 521 NQLKEARLLAEDADGKSDEV 580
+ E LA+ + +EV
Sbjct: 1176 HMETERLELAQKLNENYEEV 1195
Score = 40.7 bits (91), Expect = 0.005
Identities = 29/117 (24%), Positives = 69/117 (58%), Gaps = 14/117 (11%)
Frame = +2
Query: 89 DAIKKKMQAMKLEKDNAMD-----KADTCE--QQARDANLRAEKVNEEVRELQKKLAQ-- 241
D +++ + +KLE+D + KA E Q+ + A + +++ E V +L++K+++
Sbjct: 1892 DNLRRVEETLKLERDQLKESLQETKARDLEIQQELKTARMLSKEHKETVDKLREKISEKT 1951
Query: 242 -----VEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEE 397
+++DL +K++L++ ++L++KE QL + +V ++K+ ++E+ L+K E
Sbjct: 1952 IQISDIQKDLDKSKDELQKKIQELQKKELQLLRVKEDVNMSHKKINEMEQ-LKKQFE 2007
Score = 39.1 bits (87), Expect = 0.016
Identities = 29/135 (21%), Positives = 68/135 (50%), Gaps = 10/135 (7%)
Frame = +2
Query: 161 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 340
++ + + A++ N +++ + +L++ + L + KL++ ++ L+EK++QL + E+
Sbjct: 1092 DELKKQQEIVAQEKNHAIKK-EGELSRTCDRLAEVEEKLKEKSQQLQEKQQQLLNVQEEM 1150
Query: 341 AALNRKVQQIEE---DLEKSEERSGTAQQKLLEAQQSADEN-------NRMCKVLENRAQ 490
+ + +K+ +IE +L+ E + + LE Q +EN + KVL+ +
Sbjct: 1151 SEMQKKINEIENLKNELKNKELTLEHMETERLELAQKLNENYEEVKSITKERKVLKELQK 1210
Query: 491 QDEERMDQLTNQLKE 535
E D L ++E
Sbjct: 1211 SFETERDHLRGYIRE 1225
Score = 36.3 bits (80), Expect = 0.11
Identities = 25/117 (21%), Positives = 55/117 (47%), Gaps = 3/117 (2%)
Frame = +2
Query: 194 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIE 373
E++N+E+ L K+ + + L K +L ++L+EK +++ E+ L +++ +
Sbjct: 841 ERMNQEIVNLSKEAQKFDSSLGALKTELSYKTQELQEKTREVQERLNEMEQLKEQLENRD 900
Query: 374 EDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEE---RMDQLTNQLKE 535
L+ E +KL QQ+ +E + + ++ Q E DQL + + +
Sbjct: 901 SPLQTVEREKTLITEKL---QQTLEEVKTLTQEKDDLKQLQESLQIERDQLKSDIHD 954
Score = 31.5 bits (68), Expect = 3.2
Identities = 34/179 (18%), Positives = 82/179 (45%), Gaps = 6/179 (3%)
Frame = +2
Query: 98 KKKMQAMKLEKD--NAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEE-DLILNK 268
+K +Q ++KD + D+ Q+ + L+ +V E+V KK+ ++E+
Sbjct: 1949 EKTIQISDIQKDLDKSKDELQKKIQELQKKELQLLRVKEDVNMSHKKINEMEQLKKQFEP 2008
Query: 269 NKLEQANKDLEEKEKQL--TATEAEVAALNR-KVQQIEEDLEKSEERSGTAQQKLLEAQQ 439
N L + D + K+L + E + A R ++++I+E L+ ++ ++++ +
Sbjct: 2009 NYLCKCEMDNFQLTKKLHESLEEIRIVAKERDELRRIKESLKMERDQFIATLREMIARDR 2068
Query: 440 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELE 616
+ ++L + Q E + + +++KE + D + ++R +E E+E
Sbjct: 2069 QNHQVKPEKRLLSDGQQHLMESLREKCSRIKELLKRYSEMDDHYECLNRLSLDLEKEIE 2127
Score = 31.5 bits (68), Expect = 3.2
Identities = 34/156 (21%), Positives = 67/156 (42%), Gaps = 2/156 (1%)
Frame = +2
Query: 194 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIE 373
EK+ +++ ++ QV N + N+ E +E+ T ++ + ++ ++
Sbjct: 2245 EKLKNGIQKENDRICQVNN--FFNNRIIAIMNESTEFEERSATISKE----WEQDLKSLK 2298
Query: 374 EDLEKSEERSGTAQQKLLEAQQ--SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLL 547
E EK + T + L Q ++N+ V Q E++ +L N L EA+
Sbjct: 2299 EKNEKLFKNYQTLKTSLASGAQVNPTTQDNKNPHVTSRATQLTTEKIRELENSLHEAK-- 2356
Query: 548 AEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKI 655
E A K ++ + ++ ELEV D + AK+
Sbjct: 2357 -ESAMHKESKIIK----MQKELEVTNDIIAKLQAKV 2387
>X69292-1|CAA49154.1| 881|Homo sapiens smooth muscle mysosin heavy
chain protein.
Length = 881
Score = 55.2 bits (127), Expect = 2e-07
Identities = 38/200 (19%), Positives = 98/200 (49%), Gaps = 5/200 (2%)
Frame = +2
Query: 95 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 274
++ ++ ++ E + + + R A +AE+++ E+ ++ AQ E ++ +
Sbjct: 643 LEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELAT-ERSTAQKNES---SRQQ 698
Query: 275 LEQANKDLEEKEKQLTAT-----EAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 439
LE+ NK+L K ++ ++ +AAL K+ Q+EE +E+ A + L + +
Sbjct: 699 LERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDK 758
Query: 440 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 619
E + A+Q +E+ ++ ++K+ + E+A+ +S ++ ++ EL+
Sbjct: 759 KLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDE 818
Query: 620 AEDRVKSGDAKISXLEXELK 679
A + ++ +++ L+ +L+
Sbjct: 819 ATESNEAMGREVNALKSKLR 838
Score = 50.0 bits (114), Expect = 9e-06
Identities = 38/215 (17%), Positives = 98/215 (45%), Gaps = 12/215 (5%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQA----MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKL 235
+++ A A KKK++ ++L+ D+A+ + +Q R + + E+ + +
Sbjct: 518 RKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASR 577
Query: 236 AQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKS-------E 394
++ N+ K + DL + ++ L A E + + +++ E+L S +
Sbjct: 578 DEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQ 637
Query: 395 ERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSD 574
+ + ++ + ++ +E + + +R ++ ++ +QL+N+L R A+ +
Sbjct: 638 DEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESSRQ 697
Query: 575 EVSRKLAFVEDELEVAEDRVKSG-DAKISXLEXEL 676
++ R+ + +L E VKS + I+ LE ++
Sbjct: 698 QLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKI 732
Score = 46.4 bits (105), Expect = 1e-04
Identities = 37/185 (20%), Positives = 81/185 (43%), Gaps = 1/185 (0%)
Frame = +2
Query: 95 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 274
++++ +++ + D M+ E+ N++ +++++ + +EE + +
Sbjct: 250 LEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKE 309
Query: 275 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ-SADE 451
+E + EEK E L +++ + DL+ + ++K + Q A+E
Sbjct: 310 IENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEE 369
Query: 452 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDR 631
N K + R + + E ++ T L AR L E + K +E+ R ++ E+ ED
Sbjct: 370 KNISSKYADERDRAEAEAREKETKALSLARALEEALEAK-EELERTNKMLKAEM---EDL 425
Query: 632 VKSGD 646
V S D
Sbjct: 426 VSSKD 430
Score = 45.6 bits (103), Expect = 2e-04
Identities = 38/183 (20%), Positives = 88/183 (48%), Gaps = 3/183 (1%)
Frame = +2
Query: 191 AEKVN--EEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQ 364
A+K N +++REL+ ++ ++EDL E+A ++ EK+K+ E E AL +++
Sbjct: 13 AQKNNALKKIRELEGHISDLQEDL-----DSERAARNKAEKQKRDLGEELE--ALKTELE 65
Query: 365 QIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKV-LENRAQQDEERMDQLTNQLKEAR 541
+ +E +Q++ +++ DE R + ++ Q+ + +++LT QL++ +
Sbjct: 66 DTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFK 125
Query: 542 LLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEX 721
+ D + ++ A + EL V + + K LE +++ + + E +
Sbjct: 126 RAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARA 185
Query: 722 KAN 730
+ N
Sbjct: 186 ELN 188
Score = 43.6 bits (98), Expect = 7e-04
Identities = 46/223 (20%), Positives = 101/223 (45%), Gaps = 9/223 (4%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEK--DNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQ 241
++ A +A +K+ +A+ L + + A++ + E+ + E + ++ K + +
Sbjct: 379 ERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHE 438
Query: 242 VEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQ----QIEEDLEKSEERSGT 409
+E+ + ++E+ LEE E +L ATE L +Q Q E DL+ +E++
Sbjct: 439 LEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEE 498
Query: 410 AQQKL---LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEV 580
+++L L ++ E+ R + L A++ +L LK+ L A+ A +E
Sbjct: 499 KRRQLQRQLHEYETELEDERKQRALAAAAKK------KLEGDLKDLELQADSAIKGREEA 552
Query: 581 SRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLE 709
++L ++ +++ + ++ A + K KSLE
Sbjct: 553 IKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLE 595
Score = 38.7 bits (86), Expect = 0.021
Identities = 33/129 (25%), Positives = 65/129 (50%), Gaps = 1/129 (0%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
++K A ++K+K + +K D+ EQ +AEK N V++L+++L + E
Sbjct: 744 REKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKE----QAEKGNARVKQLKRQLEEAE 799
Query: 248 ED-LILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL 424
E+ +N N+ + ++L+E + A EV AL K+++ E RSG +++
Sbjct: 800 EESQRINANR-RKLQRELDEATESNEAMGREVNALKSKLRRGNETSFVPSRRSG--GRRV 856
Query: 425 LEAQQSADE 451
+E ++E
Sbjct: 857 IENADGSEE 865
>AB209996-1|BAE06078.1| 2585|Homo sapiens CENPE variant protein
protein.
Length = 2585
Score = 55.2 bits (127), Expect = 2e-07
Identities = 44/198 (22%), Positives = 98/198 (49%), Gaps = 8/198 (4%)
Frame = +2
Query: 86 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 265
M + K++Q E + + D ++ ++++ E ++E+ K + EE+L +
Sbjct: 1403 MLGLSKRLQESHDEMKSVAKEKDDLQRLQEVLQSESDQLKENIKEIVAKHLETEEELKVA 1462
Query: 266 ----KNKLEQANK---DLEEKEKQLTATEAEVAALNRKVQ-QIEEDLEKSEERSGTAQQK 421
K + E N+ +L EKE +++ + ++ A+N K+Q +I+E EK E+ + +
Sbjct: 1463 HCCLKEQEETINELRVNLSEKETEISTIQKQLEAINDKLQNKIQEIYEKEEQFNIKQISE 1522
Query: 422 LLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFV 601
+ E + K ++ Q E +M +LTN+L+E++ + + +E+ R V
Sbjct: 1523 VQEKVNELKQFKEHRKAKDSALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKR----V 1578
Query: 602 EDELEVAEDRVKSGDAKI 655
++ L++ D++K +I
Sbjct: 1579 QEALQIERDQLKENTKEI 1596
Score = 44.4 bits (100), Expect = 4e-04
Identities = 44/183 (24%), Positives = 88/183 (48%), Gaps = 4/183 (2%)
Frame = +2
Query: 191 AEKVNEEVRELQKKLAQVEEDLILNKNKLEQ----ANKDLEEKEKQLTATEAEVAALNRK 358
+EK NE + +QK L + L K+++ A+ L+E+++ + V+ K
Sbjct: 1725 SEKTNE-ISNMQKDLEHSNDALKAQDLKIQEELRIAHMHLKEQQETIDKLRGIVSEKTDK 1783
Query: 359 VQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEA 538
+ +++DLE S + Q+K+ E + + + + K + N Q+ M+QL Q+K+
Sbjct: 1784 LSNMQKDLENSNAK---LQEKIQELKANEHQLITLKKDV-NETQKKVSEMEQLKKQIKDQ 1839
Query: 539 RLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSE 718
L + ++ +++KL + LE + +K D + +E LK+ + LK + E
Sbjct: 1840 SLTLSKLEIENLNLAQKL---HENLEEMKSVMKERD-NLRRVEETLKLERDQLKE-SLQE 1894
Query: 719 XKA 727
KA
Sbjct: 1895 TKA 1897
Score = 41.5 bits (93), Expect = 0.003
Identities = 38/185 (20%), Positives = 87/185 (47%), Gaps = 7/185 (3%)
Frame = +2
Query: 143 DKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK---LEQANKDLEEKEK 313
+K QQ ++ + V EE+ E+QKK+ ++E KNK LE + E +
Sbjct: 1107 EKLKEKSQQLQEKQQQLLNVQEEMSEMQKKINEIENLKNELKNKELTLEHMETERLELAQ 1166
Query: 314 QLTATEAEVAALNRKVQQIEEDLEKS-EERSGTAQQKLLEAQQSADENNRMCKVLENRAQ 490
+L EV ++ K +++ ++L+KS E + + E + + + K+ +
Sbjct: 1167 KLNENYEEVKSIT-KERKVLKELQKSFETERDHLRGYIREIEATGLQTKEELKIAHIHLK 1225
Query: 491 QDEERMDQLTNQLKE--ARLL-AEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISX 661
+ +E +D+L + E A+++ +D + ++ ++ + +E E+ + + + + +
Sbjct: 1226 EHQETIDELRRSVSEKTAQIINTQDLEKSHTKLQEEIPVLHEEQELLPNVKEVSETQETM 1285
Query: 662 LEXEL 676
E EL
Sbjct: 1286 NELEL 1290
Score = 40.7 bits (91), Expect = 0.005
Identities = 26/140 (18%), Positives = 66/140 (47%)
Frame = +2
Query: 161 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 340
+Q E++ +++E + + +E+L L ++L++ + + +++ E E+
Sbjct: 1036 QQMLESVIAEKEQLKTDLKENIEMTIENQEELRLLGDELKKQQEIVAQEKNHAIKKEGEL 1095
Query: 341 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 520
+ ++ ++EE L++ ++ QQ+LL Q+ E + +EN + + + L
Sbjct: 1096 SRTCDRLAEVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQKKINEIENLKNELKNKELTLE 1155
Query: 521 NQLKEARLLAEDADGKSDEV 580
+ E LA+ + +EV
Sbjct: 1156 HMETERLELAQKLNENYEEV 1175
Score = 40.3 bits (90), Expect = 0.007
Identities = 38/172 (22%), Positives = 78/172 (45%), Gaps = 10/172 (5%)
Frame = +2
Query: 104 KMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEE------DLILN 265
K+ M+ + +N+ K Q+ + + + ++V E QKK++++E+ D L
Sbjct: 1783 KLSNMQKDLENSNAKLQEKIQELKANEHQLITLKKDVNETQKKVSEMEQLKKQIKDQSLT 1842
Query: 266 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEE--DLEKSEERSGTAQQKL--LEA 433
+KLE N +L +K + V ++++EE LE+ + + + K LE
Sbjct: 1843 LSKLEIENLNLAQKLHENLEEMKSVMKERDNLRRVEETLKLERDQLKESLQETKARDLEI 1902
Query: 434 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRK 589
QQ + K + + E++ + T Q+ + + +D D DE+ +K
Sbjct: 1903 QQELKTARMLSKEHKETVDKLREKISEKTIQISD---IQKDLDKSKDELQKK 1951
Score = 39.1 bits (87), Expect = 0.016
Identities = 29/135 (21%), Positives = 68/135 (50%), Gaps = 10/135 (7%)
Frame = +2
Query: 161 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 340
++ + + A++ N +++ + +L++ + L + KL++ ++ L+EK++QL + E+
Sbjct: 1072 DELKKQQEIVAQEKNHAIKK-EGELSRTCDRLAEVEEKLKEKSQQLQEKQQQLLNVQEEM 1130
Query: 341 AALNRKVQQIEE---DLEKSEERSGTAQQKLLEAQQSADEN-------NRMCKVLENRAQ 490
+ + +K+ +IE +L+ E + + LE Q +EN + KVL+ +
Sbjct: 1131 SEMQKKINEIENLKNELKNKELTLEHMETERLELAQKLNENYEEVKSITKERKVLKELQK 1190
Query: 491 QDEERMDQLTNQLKE 535
E D L ++E
Sbjct: 1191 SFETERDHLRGYIRE 1205
Score = 36.3 bits (80), Expect = 0.11
Identities = 25/117 (21%), Positives = 55/117 (47%), Gaps = 3/117 (2%)
Frame = +2
Query: 194 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIE 373
E++N+E+ L K+ + + L K +L ++L+EK +++ E+ L +++ +
Sbjct: 821 ERMNQEIVNLSKEAQKFDSSLGALKTELSYKTQELQEKTREVQERLNEMEQLKEQLENRD 880
Query: 374 EDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEE---RMDQLTNQLKE 535
L+ E +KL QQ+ +E + + ++ Q E DQL + + +
Sbjct: 881 STLQTVEREKTLITEKL---QQTLEEVKTLTQEKDDLKQLQESLQIERDQLKSDIHD 934
Score = 31.5 bits (68), Expect = 3.2
Identities = 34/156 (21%), Positives = 67/156 (42%), Gaps = 2/156 (1%)
Frame = +2
Query: 194 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIE 373
EK+ +++ ++ QV N + N+ E +E+ T ++ + ++ ++
Sbjct: 2167 EKLKNGIQKENDRICQVNN--FFNNRIIAIMNESTEFEERSATISKE----WEQDLKSLK 2220
Query: 374 EDLEKSEERSGTAQQKLLEAQQ--SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLL 547
E EK + T + L Q ++N+ V Q E++ +L N L EA+
Sbjct: 2221 EKNEKLFKNYQTLKTSLASGAQVNPTTQDNKNPHVTSRATQLTTEKIRELENSLHEAK-- 2278
Query: 548 AEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKI 655
E A K ++ + ++ ELEV D + AK+
Sbjct: 2279 -ESAMHKESKIIK----MQKELEVTNDIIAKLQAKV 2309
>X82834-1|CAA58041.1| 2185|Homo sapiens 256 kD golgin protein.
Length = 2185
Score = 54.8 bits (126), Expect = 3e-07
Identities = 50/220 (22%), Positives = 108/220 (49%), Gaps = 11/220 (5%)
Frame = +2
Query: 98 KKKMQAMKLEKDNAMDKADT-CEQQARDANLRAEKVN---EEVRELQKKLAQVEEDLILN 265
KKK Q+ + N + + E ++++A + E++N EE+ + K+ ++ ++ +
Sbjct: 1446 KKKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDD 1505
Query: 266 KNKLEQANKDLEEKEKQLTAT----EAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEA 433
K+K+E+ +LE + K TA E + +++ + E L+ ++ ++L++
Sbjct: 1506 KSKMEKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQK 1565
Query: 434 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDEL 613
Q E + + +NR ++ EE++ L NQ+ + E + + V+ + E+EL
Sbjct: 1566 LQHFQE---LGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEEL 1622
Query: 614 EVAEDRVKS-GDAKISXL--EXELKVVGNSLKSLEVSEXK 724
+ EDR++S AK++ L + E K+ + L E K
Sbjct: 1623 KALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEK 1662
Score = 44.0 bits (99), Expect = 6e-04
Identities = 46/222 (20%), Positives = 94/222 (42%), Gaps = 3/222 (1%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQ-- 241
Q + I+ Q + ++D+ + E + ++ + EKV ++ +E+Q+ L +
Sbjct: 915 QMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKL 974
Query: 242 VEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQK 421
++++ L K +LE +L +KEKQ A E+A N I + + + E +
Sbjct: 975 LDQEAKL-KKELENTALELSQKEKQFNAKMLEMAQANS--AGISDAVSRLETNQKEQIES 1031
Query: 422 LLEAQQSADENNRMCKVLENRAQQDEERMDQLTN-QLKEARLLAEDADGKSDEVSRKLAF 598
L E + E N + + E + Q E + ++ QL+E + K +
Sbjct: 1032 LTEVHRR--ELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKEE 1089
Query: 599 VEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXK 724
+ E+ ++ D ++ L+ +LK + SL E K
Sbjct: 1090 MNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETK 1131
Score = 42.3 bits (95), Expect = 0.002
Identities = 47/199 (23%), Positives = 86/199 (43%), Gaps = 4/199 (2%)
Frame = +2
Query: 89 DAIKKKMQAMKLEKD-NAMDKADT-CEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 262
D K K KLE D N K +T ++Q + + AE+ +V EL KL +E+
Sbjct: 1128 DETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQS 1187
Query: 263 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 442
K+ E++NK LE+K + E+A Q++ +K+E +L+ S
Sbjct: 1188 LKSSHEKSNKSLEDKSLEFKKLSEELAI------QLDICCKKTEALLEAKTNELINI-SS 1240
Query: 443 ADENNRMCKV--LENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELE 616
+ N + ++ ++R + +E + T + E + + ++ +LE
Sbjct: 1241 SKTNAILSRISHCQHRTTKVKEALLIKTCTVSELEAQLRQLTEEQNTLNISFQQATHQLE 1300
Query: 617 VAEDRVKSGDAKISXLEXE 673
E+++KS A I L E
Sbjct: 1301 EKENQIKSMKADIESLVTE 1319
Score = 41.9 bits (94), Expect = 0.002
Identities = 29/147 (19%), Positives = 72/147 (48%)
Frame = +2
Query: 95 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 274
+ +K Q +++ ++KA E + +++ EE +L KK+A+ ++DL K
Sbjct: 2005 LAQKEQELEMTIKETINKAQEVEAELLESH------QEETNQLLKKIAEKDDDL---KRT 2055
Query: 275 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 454
++ + L+ +E+++TA ++ ++Q+ + + EE G ++E Q +
Sbjct: 2056 AKRYEEILDAREEEMTAKVRDLQTQLEELQKKYQQKLEQEENPGNDNVTIMELQTQLAQK 2115
Query: 455 NRMCKVLENRAQQDEERMDQLTNQLKE 535
+ + + Q+ E++ L ++LK+
Sbjct: 2116 TTLISDSKLKEQEFREQIHNLEDRLKK 2142
Score = 40.3 bits (90), Expect = 0.007
Identities = 47/222 (21%), Positives = 96/222 (43%), Gaps = 1/222 (0%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
+ A + +K+ A LE A + A + +R + E++ E + E+ ++ ++
Sbjct: 986 ENTALELSQKEKQFNAKMLEMAQA-NSAGISDAVSRLETNQKEQI-ESLTEVHRR--ELN 1041
Query: 248 EDLILNKNKLEQANKDLEE-KEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL 424
+ + + + KL Q ++L+E E QL E EVA L +K+ EK E K
Sbjct: 1042 DVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLF--GCEKEEMNKEITWLKE 1099
Query: 425 LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVE 604
+Q N L+ + +Q ++ L + + E + ++ ++ F++
Sbjct: 1100 EGVKQDTTLNE-----LQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQ 1154
Query: 605 DELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXKAN 730
++L + + K+S L +LK +SL+ S K+N
Sbjct: 1155 EQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSN 1196
Score = 38.3 bits (85), Expect = 0.028
Identities = 37/229 (16%), Positives = 97/229 (42%), Gaps = 9/229 (3%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
Q+K + +K+K+ EK+ + +++ + ++ E++++ + +
Sbjct: 1067 QEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLA 1126
Query: 248 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAAL-------NRKVQQIEEDLEKSEERSG 406
+D K LE+ DL + K+ T + ++ L RKV ++ L+ ++E
Sbjct: 1127 QDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQ 1186
Query: 407 TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL--LAEDADGKSDEV 580
+ + ++ +S ++ + K L + + T L EA+ L + K++ +
Sbjct: 1187 SLKSSHEKSNKSLEDKSLEFKKLSEELAIQLDICCKKTEALLEAKTNELINISSSKTNAI 1246
Query: 581 SRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXKA 727
+++ + ++ + +S LE +L+ + +L +S +A
Sbjct: 1247 LSRISHCQHRTTKVKEALLIKTCTVSELEAQLRQLTEEQNTLNISFQQA 1295
>U41740-1|AAC50434.1| 2230|Homo sapiens trans-Golgi p230 protein.
Length = 2230
Score = 54.8 bits (126), Expect = 3e-07
Identities = 50/220 (22%), Positives = 108/220 (49%), Gaps = 11/220 (5%)
Frame = +2
Query: 98 KKKMQAMKLEKDNAMDKADT-CEQQARDANLRAEKVN---EEVRELQKKLAQVEEDLILN 265
KKK Q+ + N + + E ++++A + E++N EE+ + K+ ++ ++ +
Sbjct: 1446 KKKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDD 1505
Query: 266 KNKLEQANKDLEEKEKQLTAT----EAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEA 433
K+K+E+ +LE + K TA E + +++ + E L+ ++ ++L++
Sbjct: 1506 KSKMEKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQK 1565
Query: 434 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDEL 613
Q E + + +NR ++ EE++ L NQ+ + E + + V+ + E+EL
Sbjct: 1566 LQHFQE---LGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEEL 1622
Query: 614 EVAEDRVKS-GDAKISXL--EXELKVVGNSLKSLEVSEXK 724
+ EDR++S AK++ L + E K+ + L E K
Sbjct: 1623 KALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEK 1662
Score = 44.0 bits (99), Expect = 6e-04
Identities = 46/222 (20%), Positives = 94/222 (42%), Gaps = 3/222 (1%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQ-- 241
Q + I+ Q + ++D+ + E + ++ + EKV ++ +E+Q+ L +
Sbjct: 915 QMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKL 974
Query: 242 VEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQK 421
++++ L K +LE +L +KEKQ A E+A N I + + + E +
Sbjct: 975 LDQEAKL-KKELENTALELSQKEKQFNAKMLEMAQANS--AGISDAVSRLETNQKEQIES 1031
Query: 422 LLEAQQSADENNRMCKVLENRAQQDEERMDQLTN-QLKEARLLAEDADGKSDEVSRKLAF 598
L E + E N + + E + Q E + ++ QL+E + K +
Sbjct: 1032 LTEVHRR--ELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKEE 1089
Query: 599 VEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXK 724
+ E+ ++ D ++ L+ +LK + SL E K
Sbjct: 1090 MNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETK 1131
Score = 42.3 bits (95), Expect = 0.002
Identities = 47/199 (23%), Positives = 86/199 (43%), Gaps = 4/199 (2%)
Frame = +2
Query: 89 DAIKKKMQAMKLEKD-NAMDKADT-CEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 262
D K K KLE D N K +T ++Q + + AE+ +V EL KL +E+
Sbjct: 1128 DETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQS 1187
Query: 263 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 442
K+ E++NK LE+K + E+A Q++ +K+E +L+ S
Sbjct: 1188 LKSSHEKSNKSLEDKSLEFKKLSEELAI------QLDICCKKTEALLEAKTNELINI-SS 1240
Query: 443 ADENNRMCKV--LENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELE 616
+ N + ++ ++R + +E + T + E + + ++ +LE
Sbjct: 1241 SKTNAILSRISHCQHRTTKVKEALLIKTCTVSELEAQLRQLTEEQNTLNISFQQATHQLE 1300
Query: 617 VAEDRVKSGDAKISXLEXE 673
E+++KS A I L E
Sbjct: 1301 EKENQIKSMKADIESLVTE 1319
Score = 41.9 bits (94), Expect = 0.002
Identities = 29/147 (19%), Positives = 72/147 (48%)
Frame = +2
Query: 95 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 274
+ +K Q +++ ++KA E + +++ EE +L KK+A+ ++DL K
Sbjct: 2005 LAQKEQELEMTIKETINKAQEVEAELLESH------QEETNQLLKKIAEKDDDL---KRT 2055
Query: 275 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 454
++ + L+ +E+++TA ++ ++Q+ + + EE G ++E Q +
Sbjct: 2056 AKRYEEILDAREEEMTAKVRDLQTQLEELQKKYQQKLEQEENPGNDNVTIMELQTQLAQK 2115
Query: 455 NRMCKVLENRAQQDEERMDQLTNQLKE 535
+ + + Q+ E++ L ++LK+
Sbjct: 2116 TTLISDSKLKEQEFREQIHNLEDRLKK 2142
Score = 40.3 bits (90), Expect = 0.007
Identities = 47/222 (21%), Positives = 96/222 (43%), Gaps = 1/222 (0%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
+ A + +K+ A LE A + A + +R + E++ E + E+ ++ ++
Sbjct: 986 ENTALELSQKEKQFNAKMLEMAQA-NSAGISDAVSRLETNQKEQI-ESLTEVHRR--ELN 1041
Query: 248 EDLILNKNKLEQANKDLEE-KEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL 424
+ + + + KL Q ++L+E E QL E EVA L +K+ EK E K
Sbjct: 1042 DVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLF--GCEKEEMNKEITWLKE 1099
Query: 425 LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVE 604
+Q N L+ + +Q ++ L + + E + ++ ++ F++
Sbjct: 1100 EGVKQDTTLNE-----LQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQ 1154
Query: 605 DELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXKAN 730
++L + + K+S L +LK +SL+ S K+N
Sbjct: 1155 EQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSN 1196
Score = 38.3 bits (85), Expect = 0.028
Identities = 37/229 (16%), Positives = 97/229 (42%), Gaps = 9/229 (3%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
Q+K + +K+K+ EK+ + +++ + ++ E++++ + +
Sbjct: 1067 QEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLA 1126
Query: 248 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAAL-------NRKVQQIEEDLEKSEERSG 406
+D K LE+ DL + K+ T + ++ L RKV ++ L+ ++E
Sbjct: 1127 QDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQ 1186
Query: 407 TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL--LAEDADGKSDEV 580
+ + ++ +S ++ + K L + + T L EA+ L + K++ +
Sbjct: 1187 SLKSSHEKSNKSLEDKSLEFKKLSEELAIQLDICCKKTEALLEAKTNELINISSSKTNAI 1246
Query: 581 SRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXKA 727
+++ + ++ + +S LE +L+ + +L +S +A
Sbjct: 1247 LSRISHCQHRTTKVKEALLIKTCTVSELEAQLRQLTEEQNTLNISFQQA 1295
>U31906-1|AAC51791.1| 2083|Homo sapiens golgin-245 protein.
Length = 2083
Score = 54.8 bits (126), Expect = 3e-07
Identities = 50/220 (22%), Positives = 108/220 (49%), Gaps = 11/220 (5%)
Frame = +2
Query: 98 KKKMQAMKLEKDNAMDKADT-CEQQARDANLRAEKVN---EEVRELQKKLAQVEEDLILN 265
KKK Q+ + N + + E ++++A + E++N EE+ + K+ ++ ++ +
Sbjct: 1301 KKKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDD 1360
Query: 266 KNKLEQANKDLEEKEKQLTAT----EAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEA 433
K+K+E+ +LE + K TA E + +++ + E L+ ++ ++L++
Sbjct: 1361 KSKMEKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQK 1420
Query: 434 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDEL 613
Q E + + +NR ++ EE++ L NQ+ + E + + V+ + E+EL
Sbjct: 1421 LQHFQE---LGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEEL 1477
Query: 614 EVAEDRVKS-GDAKISXL--EXELKVVGNSLKSLEVSEXK 724
+ EDR++S AK++ L + E K+ + L E K
Sbjct: 1478 KALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEK 1517
Score = 44.0 bits (99), Expect = 6e-04
Identities = 46/222 (20%), Positives = 94/222 (42%), Gaps = 3/222 (1%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQ-- 241
Q + I+ Q + ++D+ + E + ++ + EKV ++ +E+Q+ L +
Sbjct: 770 QMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKL 829
Query: 242 VEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQK 421
++++ L K +LE +L +KEKQ A E+A N I + + + E +
Sbjct: 830 LDQEAKL-KKELENTALELSQKEKQFNAKMLEMAQANS--AGISDAVSRLETNQKEQIES 886
Query: 422 LLEAQQSADENNRMCKVLENRAQQDEERMDQLTN-QLKEARLLAEDADGKSDEVSRKLAF 598
L E + E N + + E + Q E + ++ QL+E + K +
Sbjct: 887 LTEVHRR--ELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKEE 944
Query: 599 VEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXK 724
+ E+ ++ D ++ L+ +LK + SL E K
Sbjct: 945 MNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETK 986
Score = 42.3 bits (95), Expect = 0.002
Identities = 47/199 (23%), Positives = 86/199 (43%), Gaps = 4/199 (2%)
Frame = +2
Query: 89 DAIKKKMQAMKLEKD-NAMDKADT-CEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 262
D K K KLE D N K +T ++Q + + AE+ +V EL KL +E+
Sbjct: 983 DETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQS 1042
Query: 263 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 442
K+ E++NK LE+K + E+A Q++ +K+E +L+ S
Sbjct: 1043 LKSSHEKSNKSLEDKSLEFKKLSEELAI------QLDICCKKTEALLEAKTNELINI-SS 1095
Query: 443 ADENNRMCKV--LENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELE 616
+ N + ++ ++R + +E + T + E + + ++ +LE
Sbjct: 1096 SKTNAILSRISHCQHRTTKVKEALLIKTCTVSELEAQLRQLTEEQNTLNISFQQATHQLE 1155
Query: 617 VAEDRVKSGDAKISXLEXE 673
E+++KS A I L E
Sbjct: 1156 EKENQIKSMKADIESLVTE 1174
Score = 41.9 bits (94), Expect = 0.002
Identities = 29/147 (19%), Positives = 72/147 (48%)
Frame = +2
Query: 95 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 274
+ +K Q +++ ++KA E + +++ EE +L KK+A+ ++DL K
Sbjct: 1860 LAQKEQELEMTIKETINKAQEVEAELLESH------QEETNQLLKKIAEKDDDL---KRT 1910
Query: 275 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 454
++ + L+ +E+++TA ++ ++Q+ + + EE G ++E Q +
Sbjct: 1911 AKRYEEILDAREEEMTAKVRDLQTQLEELQKKYQQKLEQEENPGNDNVTIMELQTQLAQK 1970
Query: 455 NRMCKVLENRAQQDEERMDQLTNQLKE 535
+ + + Q+ E++ L ++LK+
Sbjct: 1971 TTLISDSKLKEQEFREQIHNLEDRLKK 1997
Score = 40.3 bits (90), Expect = 0.007
Identities = 47/222 (21%), Positives = 96/222 (43%), Gaps = 1/222 (0%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
+ A + +K+ A LE A + A + +R + E++ E + E+ ++ ++
Sbjct: 841 ENTALELSQKEKQFNAKMLEMAQA-NSAGISDAVSRLETNQKEQI-ESLTEVHRR--ELN 896
Query: 248 EDLILNKNKLEQANKDLEE-KEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL 424
+ + + + KL Q ++L+E E QL E EVA L +K+ EK E K
Sbjct: 897 DVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLF--GCEKEEMNKEITWLKE 954
Query: 425 LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVE 604
+Q N L+ + +Q ++ L + + E + ++ ++ F++
Sbjct: 955 EGVKQDTTLNE-----LQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQ 1009
Query: 605 DELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXKAN 730
++L + + K+S L +LK +SL+ S K+N
Sbjct: 1010 EQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSN 1051
Score = 38.3 bits (85), Expect = 0.028
Identities = 37/229 (16%), Positives = 97/229 (42%), Gaps = 9/229 (3%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
Q+K + +K+K+ EK+ + +++ + ++ E++++ + +
Sbjct: 922 QEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLA 981
Query: 248 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAAL-------NRKVQQIEEDLEKSEERSG 406
+D K LE+ DL + K+ T + ++ L RKV ++ L+ ++E
Sbjct: 982 QDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQ 1041
Query: 407 TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL--LAEDADGKSDEV 580
+ + ++ +S ++ + K L + + T L EA+ L + K++ +
Sbjct: 1042 SLKSSHEKSNKSLEDKSLEFKKLSEELAIQLDICCKKTEALLEAKTNELINISSSKTNAI 1101
Query: 581 SRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXKA 727
+++ + ++ + +S LE +L+ + +L +S +A
Sbjct: 1102 LSRISHCQHRTTKVKEALLIKTCTVSELEAQLRQLTEEQNTLNISFQQA 1150
>BC101520-1|AAI01521.1| 1194|Homo sapiens protein tyrosine
phosphatase, receptor type, f polypeptide (PTPRF),
interacting protein.
Length = 1194
Score = 54.8 bits (126), Expect = 3e-07
Identities = 45/185 (24%), Positives = 89/185 (48%), Gaps = 10/185 (5%)
Frame = +2
Query: 176 DANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNR 355
D+N R ++ E + + ++ Q+ E L + ++ Q ++L ++L E + L R
Sbjct: 230 DSNRRTAELEEALERQRAEVCQLRERLAVLCRQMSQLEEELGTAHRELGKAEEANSKLQR 289
Query: 356 KVQQIEEDLEKSEERSGTAQQKLLEAQQSA----DENNRMCKVL---ENRAQQDEERMDQ 514
+++ E EER T +++ L AQ+ A D N+++ L E+ +Q EE+ Q
Sbjct: 290 DLKEALAQREDMEERITTLEKRYLSAQREATSLHDANDKLENELASKESLYRQSEEKSRQ 349
Query: 515 LTNQLKEARLLAEDADGKSD---EVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVV 685
L L +A+ + K++ E+ +LA L AE+R + + ++ LE +L+
Sbjct: 350 LAEWLDDAKQKLQQTLQKAETLPEIEAQLAQRVAALNKAEERHGNFEERLRQLEAQLEEK 409
Query: 686 GNSLK 700
L+
Sbjct: 410 NQELQ 414
Score = 40.3 bits (90), Expect = 0.007
Identities = 45/164 (27%), Positives = 81/164 (49%), Gaps = 11/164 (6%)
Frame = +2
Query: 176 DAN--LRAEKVNEE--VRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 343
DAN L E ++E R+ ++K Q+ E L K KL+Q + E + VA
Sbjct: 324 DANDKLENELASKESLYRQSEEKSRQLAEWLDDAKQKLQQTLQKAETLPEIEAQLAQRVA 383
Query: 344 ALNRKVQQ---IEEDLEKSEERSGTAQQKLLEAQQ----SADENNRMCKVLENRAQQDEE 502
ALN+ ++ EE L + E + Q+L A+Q + D N R+ + ++ + E
Sbjct: 384 ALNKAEERHGNFEERLRQLEAQLEEKNQELQRARQREKMNDDHNKRLSETVDKLLSESNE 443
Query: 503 RMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRV 634
R+ QL LKE E+ + S+E++ + ++DEL + ++++
Sbjct: 444 RL-QL--HLKERMGALEEKNSLSEEIA-NMKKLQDELLLNKEQL 483
Score = 32.3 bits (70), Expect = 1.8
Identities = 34/157 (21%), Positives = 61/157 (38%), Gaps = 12/157 (7%)
Frame = +2
Query: 194 EKVNEEVRELQKKLAQVEEDLILN-------KNKLEQANKDLEEKEKQ-----LTATEAE 337
EKV E +R +++A +EE+L L+ + +L + LEE K L
Sbjct: 168 EKVRERLRMALERVAVLEEELELSNQETLNLREQLSRRRSGLEEPGKDGDGQTLANGLGP 227
Query: 338 VAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQL 517
NR+ ++EE LE+ +++L + + + EE +L
Sbjct: 228 GGDSNRRTAELEEALERQRAEVCQLRERLAVLCRQMSQLEEELGTAHRELGKAEEANSKL 287
Query: 518 TNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAED 628
LKEA ED + + + ++ + E D
Sbjct: 288 QRDLKEALAQREDMEERITTLEKRYLSAQREATSLHD 324
>BC101518-1|AAI01519.1| 1194|Homo sapiens protein tyrosine
phosphatase, receptor type, f polypeptide (PTPRF),
interacting protein.
Length = 1194
Score = 54.8 bits (126), Expect = 3e-07
Identities = 45/185 (24%), Positives = 89/185 (48%), Gaps = 10/185 (5%)
Frame = +2
Query: 176 DANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNR 355
D+N R ++ E + + ++ Q+ E L + ++ Q ++L ++L E + L R
Sbjct: 230 DSNRRTAELEEALERQRAEVCQLRERLAVLCRQMSQLEEELGTAHRELGKAEEANSKLQR 289
Query: 356 KVQQIEEDLEKSEERSGTAQQKLLEAQQSA----DENNRMCKVL---ENRAQQDEERMDQ 514
+++ E EER T +++ L AQ+ A D N+++ L E+ +Q EE+ Q
Sbjct: 290 DLKEALAQREDMEERITTLEKRYLSAQREATSLHDANDKLENELASKESLYRQSEEKSRQ 349
Query: 515 LTNQLKEARLLAEDADGKSD---EVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVV 685
L L +A+ + K++ E+ +LA L AE+R + + ++ LE +L+
Sbjct: 350 LAEWLDDAKQKLQQTLQKAETLPEIEAQLAQRVAALNKAEERHGNFEERLRQLEAQLEEK 409
Query: 686 GNSLK 700
L+
Sbjct: 410 NQELQ 414
Score = 40.3 bits (90), Expect = 0.007
Identities = 45/164 (27%), Positives = 81/164 (49%), Gaps = 11/164 (6%)
Frame = +2
Query: 176 DAN--LRAEKVNEE--VRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 343
DAN L E ++E R+ ++K Q+ E L K KL+Q + E + VA
Sbjct: 324 DANDKLENELASKESLYRQSEEKSRQLAEWLDDAKQKLQQTLQKAETLPEIEAQLAQRVA 383
Query: 344 ALNRKVQQ---IEEDLEKSEERSGTAQQKLLEAQQ----SADENNRMCKVLENRAQQDEE 502
ALN+ ++ EE L + E + Q+L A+Q + D N R+ + ++ + E
Sbjct: 384 ALNKAEERHGNFEERLRQLEAQLEEKNQELQRARQREKMNDDHNKRLSETVDKLLSESNE 443
Query: 503 RMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRV 634
R+ QL LKE E+ + S+E++ + ++DEL + ++++
Sbjct: 444 RL-QL--HLKERMGALEEKNSLSEEIA-NMKKLQDELLLNKEQL 483
Score = 32.3 bits (70), Expect = 1.8
Identities = 34/157 (21%), Positives = 61/157 (38%), Gaps = 12/157 (7%)
Frame = +2
Query: 194 EKVNEEVRELQKKLAQVEEDLILN-------KNKLEQANKDLEEKEKQ-----LTATEAE 337
EKV E +R +++A +EE+L L+ + +L + LEE K L
Sbjct: 168 EKVRERLRMALERVAVLEEELELSNQETLNLREQLSRRRSGLEEPGKDGDGQTLANGLGP 227
Query: 338 VAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQL 517
NR+ ++EE LE+ +++L + + + EE +L
Sbjct: 228 GGDSNRRTAELEEALERQRAEVCQLRERLAVLCRQMSQLEEELGTAHRELGKAEEANSKL 287
Query: 518 TNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAED 628
LKEA ED + + + ++ + E D
Sbjct: 288 QRDLKEALAQREDMEERITTLEKRYLSAQREATSLHD 324
>AB014554-1|BAA31629.2| 1267|Homo sapiens KIAA0654 protein protein.
Length = 1267
Score = 54.8 bits (126), Expect = 3e-07
Identities = 45/185 (24%), Positives = 89/185 (48%), Gaps = 10/185 (5%)
Frame = +2
Query: 176 DANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNR 355
D+N R ++ E + + ++ Q+ E L + ++ Q ++L ++L E + L R
Sbjct: 303 DSNRRTAELEEALERQRAEVCQLRERLAVLCRQMSQLEEELGTAHRELGKAEEANSKLQR 362
Query: 356 KVQQIEEDLEKSEERSGTAQQKLLEAQQSA----DENNRMCKVL---ENRAQQDEERMDQ 514
+++ E EER T +++ L AQ+ A D N+++ L E+ +Q EE+ Q
Sbjct: 363 DLKEALAQREDMEERITTLEKRYLSAQREATSLHDANDKLENELASKESLYRQSEEKSRQ 422
Query: 515 LTNQLKEARLLAEDADGKSD---EVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVV 685
L L +A+ + K++ E+ +LA L AE+R + + ++ LE +L+
Sbjct: 423 LAEWLDDAKQKLQQTLQKAETLPEIEAQLAQRVAALNKAEERHGNFEERLRQLEAQLEEK 482
Query: 686 GNSLK 700
L+
Sbjct: 483 NQELQ 487
Score = 40.3 bits (90), Expect = 0.007
Identities = 45/164 (27%), Positives = 81/164 (49%), Gaps = 11/164 (6%)
Frame = +2
Query: 176 DAN--LRAEKVNEE--VRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 343
DAN L E ++E R+ ++K Q+ E L K KL+Q + E + VA
Sbjct: 397 DANDKLENELASKESLYRQSEEKSRQLAEWLDDAKQKLQQTLQKAETLPEIEAQLAQRVA 456
Query: 344 ALNRKVQQ---IEEDLEKSEERSGTAQQKLLEAQQ----SADENNRMCKVLENRAQQDEE 502
ALN+ ++ EE L + E + Q+L A+Q + D N R+ + ++ + E
Sbjct: 457 ALNKAEERHGNFEERLRQLEAQLEEKNQELQRARQREKMNDDHNKRLSETVDKLLSESNE 516
Query: 503 RMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRV 634
R+ QL LKE E+ + S+E++ + ++DEL + ++++
Sbjct: 517 RL-QL--HLKERMGALEEKNSLSEEIA-NMKKLQDELLLNKEQL 556
Score = 32.3 bits (70), Expect = 1.8
Identities = 34/157 (21%), Positives = 61/157 (38%), Gaps = 12/157 (7%)
Frame = +2
Query: 194 EKVNEEVRELQKKLAQVEEDLILN-------KNKLEQANKDLEEKEKQ-----LTATEAE 337
EKV E +R +++A +EE+L L+ + +L + LEE K L
Sbjct: 241 EKVRERLRMALERVAVLEEELELSNQETLNLREQLSRRRSGLEEPGKDGDGQTLANGLGP 300
Query: 338 VAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQL 517
NR+ ++EE LE+ +++L + + + EE +L
Sbjct: 301 GGDSNRRTAELEEALERQRAEVCQLRERLAVLCRQMSQLEEELGTAHRELGKAEEANSKL 360
Query: 518 TNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAED 628
LKEA ED + + + ++ + E D
Sbjct: 361 QRDLKEALAQREDMEERITTLEKRYLSAQREATSLHD 397
>X03741-1|CAA27381.1| 635|Homo sapiens protein ( Human cardiac mRNA
for myosin heavy chain light meromyosin region. ).
Length = 635
Score = 54.4 bits (125), Expect = 4e-07
Identities = 40/190 (21%), Positives = 79/190 (41%)
Frame = +2
Query: 161 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 340
+ + D + E+ N L KK ++ L K K E++ +LE +K+ + E+
Sbjct: 122 QNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTEL 181
Query: 341 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 520
L ++ E LE + + Q+++ + + + + LE +Q E +L
Sbjct: 182 FKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQ 241
Query: 521 NQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLK 700
+ L+EA E +GK + +L F + + E+ R + + L+VV +
Sbjct: 242 SALEEAEASLEHEEGKI--LRAQLEFNQIKAEIERKRQEKDEEMEQAKRNHLRVVDSLQT 299
Query: 701 SLEVSEXKAN 730
SL+ N
Sbjct: 300 SLDAETRSRN 309
Score = 50.0 bits (114), Expect = 9e-06
Identities = 56/223 (25%), Positives = 102/223 (45%), Gaps = 9/223 (4%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAE--KVNEEVRELQKKLAQ 241
+++ +A+ +Q+ + + D ++ + E+ A L+ + K N EV + + K
Sbjct: 20 EEEVKAKNALAHALQSARHDCDLLREQYE--EETEAKARLQGDLSKANSEVAQWRTKY-- 75
Query: 242 VEEDLILNKNKLEQANKDL----EEKEKQLTATEAEVAALNRKVQQIE---EDLEKSEER 400
E D I +LE+A K L +E E+ + A A+ ++L + +++ EDL ER
Sbjct: 76 -ETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVER 134
Query: 401 SGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEV 580
S A L + Q++ D K+L Q+ EE +L + KEAR L+ + +
Sbjct: 135 SNAAAAALDKKQRNFD------KILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAY 188
Query: 581 SRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLE 709
L + LE + K+ +IS L +L G ++ LE
Sbjct: 189 EESL----EHLETFKRENKNLQEEISDLTEQLGSSGKTIHELE 227
Score = 47.2 bits (107), Expect = 6e-05
Identities = 53/228 (23%), Positives = 110/228 (48%), Gaps = 14/228 (6%)
Frame = +2
Query: 86 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAE-KVNEEVRELQKKLAQVEEDLIL 262
++ ++K+++A K+E +A+++A+ + LRA+ + N+ E+++K + +E+
Sbjct: 226 LEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKRQEKDEE--- 282
Query: 263 NKNKLEQANKD-LEEKEKQLTATEAEVAALN---RKVQQIEEDLEKSEERSGTAQQKLLE 430
+EQA ++ L + T+ +AE + N R +++E DL + E + A + E
Sbjct: 283 ----MEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAE 338
Query: 431 AQQSADENNRMCK----VLENRAQQDEERMDQLT-----NQLKEARLLAEDADGKSDEVS 583
AQ+ + K L++ + +++ + + N L +A L A + E S
Sbjct: 339 AQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERS 398
Query: 584 RKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXKA 727
RKLA E EL +RV+ ++ + L + K + L L+ +A
Sbjct: 399 RKLA--EQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEA 444
>U80458-1|AAD00355.1| 1604|Homo sapiens microtubule associated protein
1A protein.
Length = 1604
Score = 54.4 bits (125), Expect = 4e-07
Identities = 55/200 (27%), Positives = 96/200 (48%), Gaps = 4/200 (2%)
Frame = +2
Query: 122 LEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLE 301
LE ++ DT Q +D L + NE V++ K L Q DL LEQ +K LE
Sbjct: 1291 LEHKEVVEPKDTAIYQ-KDEALHVK--NEAVKQQDKALEQKGRDLEQKDTALEQKDKALE 1347
Query: 302 EKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN-NRMCKVLE 478
K+K L E + AL +K +I E+ +K+ E+ TA ++ + + D++ + +VLE
Sbjct: 1348 PKDKDL---EEKDKALEQK-DKIPEEKDKALEQKDTALEQKDKTLEPKDKDLEQKDRVLE 1403
Query: 479 NRAQQDEERMDQLTNQLKEARLLA-ED--ADGKSDEVSRKLAFVEDELEVAEDRVKSGDA 649
+ + EE+ L +++ A ED A+ K ++ + E + + E + K +
Sbjct: 1404 QKEKIPEEKDKALDQKVRSVEHKAPEDTVAEMKDRDLEQTDKAPEQKHQAQEQKDKVSEK 1463
Query: 650 KISXLEXELKVVGNSLKSLE 709
K LE + +G ++LE
Sbjct: 1464 KDQALEQKYWALGQKDEALE 1483
Score = 49.2 bits (112), Expect = 2e-05
Identities = 51/207 (24%), Positives = 101/207 (48%), Gaps = 6/207 (2%)
Frame = +2
Query: 125 EKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEE 304
EKD A+++ D ++ +D L E+ + + + K L ++DL LEQ K EE
Sbjct: 1355 EKDKALEQKDKIPEE-KDKAL--EQKDTALEQKDKTLEPKDKDLEQKDRVLEQKEKIPEE 1411
Query: 305 KEKQLTATEAEVAALNRKVQQ--IEEDLEKSEERSGTAQQKLLEAQQSADE-NNRMCKVL 475
K+K A + +V ++ K + + E ++ E++ A ++ +AQ+ D+ + + + L
Sbjct: 1412 KDK---ALDQKVRSVEHKAPEDTVAEMKDRDLEQTDKAPEQKHQAQEQKDKVSEKKDQAL 1468
Query: 476 ENR---AQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGD 646
E + Q +E ++Q L+E E ++ +RK +E E + ++VK+ +
Sbjct: 1469 EQKYWALGQKDEALEQNIQALEENHQTQEQESLVQEDKTRKPKMLE---EKSPEKVKAME 1525
Query: 647 AKISXLEXELKVVGNSLKSLEVSEXKA 727
K+ L + K +G L+ V E +A
Sbjct: 1526 EKLEALLEKTKALG--LEESLVQEGRA 1550
Score = 38.3 bits (85), Expect = 0.028
Identities = 33/149 (22%), Positives = 73/149 (48%)
Frame = +2
Query: 89 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 268
D + ++ + + EKD A+D Q+ R +A + + V E++ + + + K
Sbjct: 1399 DRVLEQKEKIPEEKDKALD------QKVRSVEHKAPE--DTVAEMKDRDLEQTDKAPEQK 1450
Query: 269 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSAD 448
++ ++ + EK+ Q A E + AL +K + +E++++ EE T +Q+ L +
Sbjct: 1451 HQAQEQKDKVSEKKDQ--ALEQKYWALGQKDEALEQNIQALEENHQTQEQESL----VQE 1504
Query: 449 ENNRMCKVLENRAQQDEERMDQLTNQLKE 535
+ R K+LE ++ + + M++ L E
Sbjct: 1505 DKTRKPKMLEEKSPEKVKAMEEKLEALLE 1533
>D10667-1|BAA36971.1| 1052|Homo sapiens smooth muscle myosin heavy
chain protein.
Length = 1052
Score = 54.4 bits (125), Expect = 4e-07
Identities = 38/200 (19%), Positives = 97/200 (48%), Gaps = 5/200 (2%)
Frame = +2
Query: 95 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 274
++ ++ ++ E + + + R A +AE+++ E+ ++ AQ E + +
Sbjct: 848 LEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELAT-ERSTAQKNESA---RQQ 903
Query: 275 LEQANKDLEEKEKQLTAT-----EAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 439
LE+ NK+L K ++ ++ +AAL K+ Q+EE +E+ A + L + +
Sbjct: 904 LERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDK 963
Query: 440 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 619
E + A+Q +E+ ++ ++K+ + E+A+ +S ++ ++ EL+
Sbjct: 964 KLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDE 1023
Query: 620 AEDRVKSGDAKISXLEXELK 679
A + ++ +++ L+ +L+
Sbjct: 1024 ATESNEAMGREVNALKSKLR 1043
Score = 49.2 bits (112), Expect = 2e-05
Identities = 35/208 (16%), Positives = 94/208 (45%), Gaps = 8/208 (3%)
Frame = +2
Query: 77 AATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDL 256
AA ++ ++ ++L+ D+A+ + +Q R + + E+ + + ++
Sbjct: 730 AAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATA 789
Query: 257 ILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKS-------EERSGTAQ 415
N+ K + DL + ++ L A E + + +++ E+L S ++ +
Sbjct: 790 KENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLE 849
Query: 416 QKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLA 595
++ + ++ +E + + +R ++ ++ +QL+N+L R A+ + ++ R+
Sbjct: 850 ARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNK 909
Query: 596 FVEDELEVAEDRVKSG-DAKISXLEXEL 676
+ +L E VKS + I+ LE ++
Sbjct: 910 ELRSKLHEMEGAVKSKFKSTIAALEAKI 937
Score = 46.4 bits (105), Expect = 1e-04
Identities = 37/185 (20%), Positives = 81/185 (43%), Gaps = 1/185 (0%)
Frame = +2
Query: 95 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 274
++++ +++ + D M+ E+ N++ +++++ + +EE + +
Sbjct: 455 LEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKE 514
Query: 275 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ-SADE 451
+E + EEK E L +++ + DL+ + ++K + Q A+E
Sbjct: 515 IENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEE 574
Query: 452 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDR 631
N K + R + + E ++ T L AR L E + K +E+ R ++ E+ ED
Sbjct: 575 KNISSKYADERDRAEAEAREKETKALSLARALEEALEAK-EELERTNKMLKAEM---EDL 630
Query: 632 VKSGD 646
V S D
Sbjct: 631 VSSKD 635
Score = 46.4 bits (105), Expect = 1e-04
Identities = 36/178 (20%), Positives = 83/178 (46%), Gaps = 4/178 (2%)
Frame = +2
Query: 107 MQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQA 286
++A++ K + + QQ + +K+ + LQ++L +DL+++ + Q
Sbjct: 501 VEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQEL----DDLVVDLDNQRQL 556
Query: 287 NKDLEEKEKQLTATEAEVAALNRKV----QQIEEDLEKSEERSGTAQQKLLEAQQSADEN 454
+LE+K+++ AE ++ K + E + + E ++ + + L EA ++ +E
Sbjct: 557 VSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEEL 616
Query: 455 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAED 628
R K+L+ + D + + E + + +E+ +L +EDEL+ +ED
Sbjct: 617 ERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQASED 674
Score = 42.3 bits (95), Expect = 0.002
Identities = 46/181 (25%), Positives = 82/181 (45%)
Frame = +2
Query: 182 NLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKV 361
NL E++ E EL + ++ L K +LE+ ++E + ++ ++ A +K+
Sbjct: 4 NLLQEQLQAET-ELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKM 62
Query: 362 QQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEAR 541
Q DLE+ E A+QKL + +A+ K LE+ MD N+L + R
Sbjct: 63 AQQMLDLEEQLEEEEAARQKLQLEKVTAEAK---IKKLEDEILV----MDDQNNKLSKER 115
Query: 542 LLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEX 721
L E+ + +++ LA E++ + ++ IS LE LK S + LE +
Sbjct: 116 KLLEE---RISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKR 172
Query: 722 K 724
K
Sbjct: 173 K 173
Score = 41.1 bits (92), Expect = 0.004
Identities = 33/191 (17%), Positives = 82/191 (42%), Gaps = 1/191 (0%)
Frame = +2
Query: 161 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 340
E++ + A R + + KK+ ++E + + L+ + EKQ E+
Sbjct: 203 EEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEEL 262
Query: 341 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKV-LENRAQQDEERMDQL 517
AL +++ + +E +Q++ +++ DE R + ++ Q+ + +++L
Sbjct: 263 EALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEEL 322
Query: 518 TNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSL 697
T QL++ + + D + ++ A + EL V + + K LE +++ + +
Sbjct: 323 TEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKC 382
Query: 698 KSLEVSEXKAN 730
E + + N
Sbjct: 383 SDGERARAELN 393
Score = 35.1 bits (77), Expect = 0.26
Identities = 27/100 (27%), Positives = 52/100 (52%), Gaps = 1/100 (1%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
++K A ++K+K + +K D+ EQ +AEK N V++L+++L + E
Sbjct: 949 REKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKE----QAEKGNARVKQLKRQLEEAE 1004
Query: 248 ED-LILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQ 364
E+ +N N+ + ++L+E + A EV AL K++
Sbjct: 1005 EESQRINANR-RKLQRELDEATESNEAMGREVNALKSKLR 1043
>BC104906-1|AAI04907.1| 1938|Homo sapiens myosin, heavy chain 11,
smooth muscle protein.
Length = 1938
Score = 54.4 bits (125), Expect = 4e-07
Identities = 38/200 (19%), Positives = 97/200 (48%), Gaps = 5/200 (2%)
Frame = +2
Query: 95 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 274
++ ++ ++ E + + + R A +AE+++ E+ ++ AQ E + +
Sbjct: 1734 LEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELAT-ERSTAQKNESA---RQQ 1789
Query: 275 LEQANKDLEEKEKQLTAT-----EAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 439
LE+ NK+L K ++ ++ +AAL K+ Q+EE +E+ A + L + +
Sbjct: 1790 LERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDK 1849
Query: 440 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 619
E + A+Q +E+ ++ ++K+ + E+A+ +S ++ ++ EL+
Sbjct: 1850 KLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDE 1909
Query: 620 AEDRVKSGDAKISXLEXELK 679
A + ++ +++ L+ +L+
Sbjct: 1910 ATESNEAMGREVNALKSKLR 1929
Score = 49.6 bits (113), Expect = 1e-05
Identities = 38/215 (17%), Positives = 98/215 (45%), Gaps = 12/215 (5%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQA----MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKL 235
+++ A A KKK++ ++L+ D+A+ + +Q R + + E+ + +
Sbjct: 1609 RKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASR 1668
Query: 236 AQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKS-------E 394
++ N+ K + DL + ++ L A E + + +++ E+L S +
Sbjct: 1669 DEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQ 1728
Query: 395 ERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSD 574
+ + ++ + ++ +E + + +R ++ ++ +QL+N+L R A+ +
Sbjct: 1729 DEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQ 1788
Query: 575 EVSRKLAFVEDELEVAEDRVKSG-DAKISXLEXEL 676
++ R+ + +L E VKS + I+ LE ++
Sbjct: 1789 QLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKI 1823
Score = 47.2 bits (107), Expect = 6e-05
Identities = 50/219 (22%), Positives = 96/219 (43%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
++ A D ++K + + ++ + Q + NL E++ E EL + ++
Sbjct: 852 EEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAET-ELYAEAEEMR 910
Query: 248 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 427
L K +LE+ ++E + ++ ++ A +K+ Q DLE+ E A+QKL
Sbjct: 911 VRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQ 970
Query: 428 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 607
+ +A+ K LE+ MD N+L + R L E+ + +++ LA E+
Sbjct: 971 LEKVTAEAK---IKKLEDEILV----MDDQNNKLSKERKLLEE---RISDLTTNLAEEEE 1020
Query: 608 ELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXK 724
+ + ++ IS LE LK S + LE + K
Sbjct: 1021 KAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRK 1059
Score = 46.4 bits (105), Expect = 1e-04
Identities = 37/185 (20%), Positives = 81/185 (43%), Gaps = 1/185 (0%)
Frame = +2
Query: 95 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 274
++++ +++ + D M+ E+ N++ +++++ + +EE + +
Sbjct: 1341 LEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKE 1400
Query: 275 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ-SADE 451
+E + EEK E L +++ + DL+ + ++K + Q A+E
Sbjct: 1401 IENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEE 1460
Query: 452 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDR 631
N K + R + + E ++ T L AR L E + K +E+ R ++ E+ ED
Sbjct: 1461 KNISSKYADERDRAEAEAREKETKALSLARALEEALEAK-EELERTNKMLKAEM---EDL 1516
Query: 632 VKSGD 646
V S D
Sbjct: 1517 VSSKD 1521
Score = 43.6 bits (98), Expect = 7e-04
Identities = 46/223 (20%), Positives = 101/223 (45%), Gaps = 9/223 (4%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEK--DNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQ 241
++ A +A +K+ +A+ L + + A++ + E+ + E + ++ K + +
Sbjct: 1470 ERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHE 1529
Query: 242 VEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQ----QIEEDLEKSEERSGT 409
+E+ + ++E+ LEE E +L ATE L +Q Q E DL+ +E++
Sbjct: 1530 LEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEE 1589
Query: 410 AQQKL---LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEV 580
+++L L ++ E+ R + L A++ +L LK+ L A+ A +E
Sbjct: 1590 KRRQLQRQLHEYETELEDERKQRALAAAAKK------KLEGDLKDLELQADSAIKGREEA 1643
Query: 581 SRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLE 709
++L ++ +++ + ++ A + K KSLE
Sbjct: 1644 IKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLE 1686
Score = 41.1 bits (92), Expect = 0.004
Identities = 33/191 (17%), Positives = 82/191 (42%), Gaps = 1/191 (0%)
Frame = +2
Query: 161 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 340
E++ + A R + + KK+ ++E + + L+ + EKQ E+
Sbjct: 1089 EEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEEL 1148
Query: 341 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKV-LENRAQQDEERMDQL 517
AL +++ + +E +Q++ +++ DE R + ++ Q+ + +++L
Sbjct: 1149 EALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEEL 1208
Query: 518 TNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSL 697
T QL++ + + D + ++ A + EL V + + K LE +++ + +
Sbjct: 1209 TEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKC 1268
Query: 698 KSLEVSEXKAN 730
E + + N
Sbjct: 1269 SDGERARAELN 1279
Score = 35.1 bits (77), Expect = 0.26
Identities = 27/100 (27%), Positives = 52/100 (52%), Gaps = 1/100 (1%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
++K A ++K+K + +K D+ EQ +AEK N V++L+++L + E
Sbjct: 1835 REKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKE----QAEKGNARVKQLKRQLEEAE 1890
Query: 248 ED-LILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQ 364
E+ +N N+ + ++L+E + A EV AL K++
Sbjct: 1891 EESQRINANR-RKLQRELDEATESNEAMGREVNALKSKLR 1929
>BC101677-1|AAI01678.1| 1938|Homo sapiens myosin, heavy chain 11,
smooth muscle protein.
Length = 1938
Score = 54.4 bits (125), Expect = 4e-07
Identities = 38/200 (19%), Positives = 97/200 (48%), Gaps = 5/200 (2%)
Frame = +2
Query: 95 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 274
++ ++ ++ E + + + R A +AE+++ E+ ++ AQ E + +
Sbjct: 1734 LEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELAT-ERSTAQKNESA---RQQ 1789
Query: 275 LEQANKDLEEKEKQLTAT-----EAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 439
LE+ NK+L K ++ ++ +AAL K+ Q+EE +E+ A + L + +
Sbjct: 1790 LERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDK 1849
Query: 440 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 619
E + A+Q +E+ ++ ++K+ + E+A+ +S ++ ++ EL+
Sbjct: 1850 KLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDE 1909
Query: 620 AEDRVKSGDAKISXLEXELK 679
A + ++ +++ L+ +L+
Sbjct: 1910 ATESNEAMGREVNALKSKLR 1929
Score = 49.6 bits (113), Expect = 1e-05
Identities = 38/215 (17%), Positives = 98/215 (45%), Gaps = 12/215 (5%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQA----MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKL 235
+++ A A KKK++ ++L+ D+A+ + +Q R + + E+ + +
Sbjct: 1609 RKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASR 1668
Query: 236 AQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKS-------E 394
++ N+ K + DL + ++ L A E + + +++ E+L S +
Sbjct: 1669 DEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQ 1728
Query: 395 ERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSD 574
+ + ++ + ++ +E + + +R ++ ++ +QL+N+L R A+ +
Sbjct: 1729 DEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQ 1788
Query: 575 EVSRKLAFVEDELEVAEDRVKSG-DAKISXLEXEL 676
++ R+ + +L E VKS + I+ LE ++
Sbjct: 1789 QLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKI 1823
Score = 47.2 bits (107), Expect = 6e-05
Identities = 50/219 (22%), Positives = 96/219 (43%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
++ A D ++K + + ++ + Q + NL E++ E EL + ++
Sbjct: 852 EEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAET-ELYAEAEEMR 910
Query: 248 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 427
L K +LE+ ++E + ++ ++ A +K+ Q DLE+ E A+QKL
Sbjct: 911 VRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQ 970
Query: 428 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 607
+ +A+ K LE+ MD N+L + R L E+ + +++ LA E+
Sbjct: 971 LEKVTAEAK---IKKLEDEILV----MDDQNNKLSKERKLLEE---RISDLTTNLAEEEE 1020
Query: 608 ELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXK 724
+ + ++ IS LE LK S + LE + K
Sbjct: 1021 KAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRK 1059
Score = 46.4 bits (105), Expect = 1e-04
Identities = 37/185 (20%), Positives = 81/185 (43%), Gaps = 1/185 (0%)
Frame = +2
Query: 95 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 274
++++ +++ + D M+ E+ N++ +++++ + +EE + +
Sbjct: 1341 LEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKE 1400
Query: 275 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ-SADE 451
+E + EEK E L +++ + DL+ + ++K + Q A+E
Sbjct: 1401 IENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEE 1460
Query: 452 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDR 631
N K + R + + E ++ T L AR L E + K +E+ R ++ E+ ED
Sbjct: 1461 KNISSKYADERDRAEAEAREKETKALSLARALEEALEAK-EELERTNKMLKAEM---EDL 1516
Query: 632 VKSGD 646
V S D
Sbjct: 1517 VSSKD 1521
Score = 43.6 bits (98), Expect = 7e-04
Identities = 46/223 (20%), Positives = 101/223 (45%), Gaps = 9/223 (4%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEK--DNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQ 241
++ A +A +K+ +A+ L + + A++ + E+ + E + ++ K + +
Sbjct: 1470 ERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHE 1529
Query: 242 VEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQ----QIEEDLEKSEERSGT 409
+E+ + ++E+ LEE E +L ATE L +Q Q E DL+ +E++
Sbjct: 1530 LEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEE 1589
Query: 410 AQQKL---LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEV 580
+++L L ++ E+ R + L A++ +L LK+ L A+ A +E
Sbjct: 1590 KRRQLQRQLHEYETELEDERKQRALAAAAKK------KLEGDLKDLELQADSAIKGREEA 1643
Query: 581 SRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLE 709
++L ++ +++ + ++ A + K KSLE
Sbjct: 1644 IKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLE 1686
Score = 41.1 bits (92), Expect = 0.004
Identities = 33/191 (17%), Positives = 82/191 (42%), Gaps = 1/191 (0%)
Frame = +2
Query: 161 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 340
E++ + A R + + KK+ ++E + + L+ + EKQ E+
Sbjct: 1089 EEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEEL 1148
Query: 341 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKV-LENRAQQDEERMDQL 517
AL +++ + +E +Q++ +++ DE R + ++ Q+ + +++L
Sbjct: 1149 EALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEEL 1208
Query: 518 TNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSL 697
T QL++ + + D + ++ A + EL V + + K LE +++ + +
Sbjct: 1209 TEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKC 1268
Query: 698 KSLEVSEXKAN 730
E + + N
Sbjct: 1269 SDGERARAELN 1279
Score = 35.1 bits (77), Expect = 0.26
Identities = 27/100 (27%), Positives = 52/100 (52%), Gaps = 1/100 (1%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
++K A ++K+K + +K D+ EQ +AEK N V++L+++L + E
Sbjct: 1835 REKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKE----QAEKGNARVKQLKRQLEEAE 1890
Query: 248 ED-LILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQ 364
E+ +N N+ + ++L+E + A EV AL K++
Sbjct: 1891 EESQRINANR-RKLQRELDEATESNEAMGREVNALKSKLR 1929
>BC080545-1|AAH80545.1| 498|Homo sapiens MYH11 protein protein.
Length = 498
Score = 54.4 bits (125), Expect = 4e-07
Identities = 38/200 (19%), Positives = 97/200 (48%), Gaps = 5/200 (2%)
Frame = +2
Query: 95 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 274
++ ++ ++ E + + + R A +AE+++ E+ ++ AQ E + +
Sbjct: 260 LEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELAT-ERSTAQKNESA---RQQ 315
Query: 275 LEQANKDLEEKEKQLTAT-----EAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 439
LE+ NK+L K ++ ++ +AAL K+ Q+EE +E+ A + L + +
Sbjct: 316 LERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDK 375
Query: 440 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 619
E + A+Q +E+ ++ ++K+ + E+A+ +S ++ ++ EL+
Sbjct: 376 KLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDE 435
Query: 620 AEDRVKSGDAKISXLEXELK 679
A + ++ +++ L+ +L+
Sbjct: 436 ATESNEAMGREVNALKSKLR 455
Score = 49.6 bits (113), Expect = 1e-05
Identities = 38/215 (17%), Positives = 98/215 (45%), Gaps = 12/215 (5%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQA----MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKL 235
+++ A A KKK++ ++L+ D+A+ + +Q R + + E+ + +
Sbjct: 135 RKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASR 194
Query: 236 AQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKS-------E 394
++ N+ K + DL + ++ L A E + + +++ E+L S +
Sbjct: 195 DEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQ 254
Query: 395 ERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSD 574
+ + ++ + ++ +E + + +R ++ ++ +QL+N+L R A+ +
Sbjct: 255 DEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQ 314
Query: 575 EVSRKLAFVEDELEVAEDRVKSG-DAKISXLEXEL 676
++ R+ + +L E VKS + I+ LE ++
Sbjct: 315 QLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKI 349
Score = 42.3 bits (95), Expect = 0.002
Identities = 45/216 (20%), Positives = 98/216 (45%), Gaps = 9/216 (4%)
Frame = +2
Query: 89 DAIKKKMQAMKLEK--DNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLIL 262
+A +K+ +A+ L + + A++ + E+ + E + ++ K + ++E+
Sbjct: 3 EAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRA 62
Query: 263 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQ----QIEEDLEKSEERSGTAQQKL-- 424
+ ++E+ LEE E +L ATE L +Q Q E DL+ +E++ +++L
Sbjct: 63 LETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQR 122
Query: 425 -LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFV 601
L ++ E+ R + L A++ +L LK+ L A+ A +E ++L +
Sbjct: 123 QLHEYETELEDERKQRALAAAAKK------KLEGDLKDLELQADSAIKGREEAIKQLRKL 176
Query: 602 EDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLE 709
+ +++ + ++ A + K KSLE
Sbjct: 177 QAQMKDFQRELEDARASRDEIFATAKENEKKAKSLE 212
Score = 38.7 bits (86), Expect = 0.021
Identities = 33/129 (25%), Positives = 65/129 (50%), Gaps = 1/129 (0%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
++K A ++K+K + +K D+ EQ +AEK N V++L+++L + E
Sbjct: 361 REKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKE----QAEKGNARVKQLKRQLEEAE 416
Query: 248 ED-LILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL 424
E+ +N N+ + ++L+E + A EV AL K+++ E RSG +++
Sbjct: 417 EESQRINANR-RKLQRELDEATESNEAMGREVNALKSKLRRGNETSFVPSRRSG--GRRV 473
Query: 425 LEAQQSADE 451
+E ++E
Sbjct: 474 IENADGSEE 482
>AY520817-1|AAS98911.1| 1945|Homo sapiens smooth muscle myosin heavy
chain isoform SM2 protein.
Length = 1945
Score = 54.4 bits (125), Expect = 4e-07
Identities = 38/200 (19%), Positives = 97/200 (48%), Gaps = 5/200 (2%)
Frame = +2
Query: 95 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 274
++ ++ ++ E + + + R A +AE+++ E+ ++ AQ E + +
Sbjct: 1741 LEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELAT-ERSTAQKNESA---RQQ 1796
Query: 275 LEQANKDLEEKEKQLTAT-----EAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 439
LE+ NK+L K ++ ++ +AAL K+ Q+EE +E+ A + L + +
Sbjct: 1797 LERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDK 1856
Query: 440 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 619
E + A+Q +E+ ++ ++K+ + E+A+ +S ++ ++ EL+
Sbjct: 1857 KLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDE 1916
Query: 620 AEDRVKSGDAKISXLEXELK 679
A + ++ +++ L+ +L+
Sbjct: 1917 ATESNEAMGREVNALKSKLR 1936
Score = 49.6 bits (113), Expect = 1e-05
Identities = 38/215 (17%), Positives = 98/215 (45%), Gaps = 12/215 (5%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQA----MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKL 235
+++ A A KKK++ ++L+ D+A+ + +Q R + + E+ + +
Sbjct: 1616 RKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASR 1675
Query: 236 AQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKS-------E 394
++ N+ K + DL + ++ L A E + + +++ E+L S +
Sbjct: 1676 DEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQ 1735
Query: 395 ERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSD 574
+ + ++ + ++ +E + + +R ++ ++ +QL+N+L R A+ +
Sbjct: 1736 DEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQ 1795
Query: 575 EVSRKLAFVEDELEVAEDRVKSG-DAKISXLEXEL 676
++ R+ + +L E VKS + I+ LE ++
Sbjct: 1796 QLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKI 1830
Score = 47.2 bits (107), Expect = 6e-05
Identities = 50/219 (22%), Positives = 96/219 (43%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
++ A D ++K + + ++ + Q + NL E++ E EL + ++
Sbjct: 859 EEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAET-ELYAEAEEMR 917
Query: 248 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 427
L K +LE+ ++E + ++ ++ A +K+ Q DLE+ E A+QKL
Sbjct: 918 VRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQ 977
Query: 428 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 607
+ +A+ K LE+ MD N+L + R L E+ + +++ LA E+
Sbjct: 978 LEKVTAEAK---IKKLEDEILV----MDDQNNKLSKERKLLEE---RISDLTTNLAEEEE 1027
Query: 608 ELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXK 724
+ + ++ IS LE LK S + LE + K
Sbjct: 1028 KAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRK 1066
Score = 46.4 bits (105), Expect = 1e-04
Identities = 37/185 (20%), Positives = 81/185 (43%), Gaps = 1/185 (0%)
Frame = +2
Query: 95 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 274
++++ +++ + D M+ E+ N++ +++++ + +EE + +
Sbjct: 1348 LEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKE 1407
Query: 275 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ-SADE 451
+E + EEK E L +++ + DL+ + ++K + Q A+E
Sbjct: 1408 IENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEE 1467
Query: 452 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDR 631
N K + R + + E ++ T L AR L E + K +E+ R ++ E+ ED
Sbjct: 1468 KNISSKYADERDRAEAEAREKETKALSLARALEEALEAK-EELERTNKMLKAEM---EDL 1523
Query: 632 VKSGD 646
V S D
Sbjct: 1524 VSSKD 1528
Score = 43.6 bits (98), Expect = 7e-04
Identities = 46/223 (20%), Positives = 101/223 (45%), Gaps = 9/223 (4%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEK--DNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQ 241
++ A +A +K+ +A+ L + + A++ + E+ + E + ++ K + +
Sbjct: 1477 ERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHE 1536
Query: 242 VEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQ----QIEEDLEKSEERSGT 409
+E+ + ++E+ LEE E +L ATE L +Q Q E DL+ +E++
Sbjct: 1537 LEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEE 1596
Query: 410 AQQKL---LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEV 580
+++L L ++ E+ R + L A++ +L LK+ L A+ A +E
Sbjct: 1597 KRRQLQRQLHEYETELEDERKQRALAAAAKK------KLEGDLKDLELQADSAIKGREEA 1650
Query: 581 SRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLE 709
++L ++ +++ + ++ A + K KSLE
Sbjct: 1651 IKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLE 1693
Score = 41.1 bits (92), Expect = 0.004
Identities = 33/191 (17%), Positives = 82/191 (42%), Gaps = 1/191 (0%)
Frame = +2
Query: 161 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 340
E++ + A R + + KK+ ++E + + L+ + EKQ E+
Sbjct: 1096 EEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEEL 1155
Query: 341 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKV-LENRAQQDEERMDQL 517
AL +++ + +E +Q++ +++ DE R + ++ Q+ + +++L
Sbjct: 1156 EALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEEL 1215
Query: 518 TNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSL 697
T QL++ + + D + ++ A + EL V + + K LE +++ + +
Sbjct: 1216 TEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKC 1275
Query: 698 KSLEVSEXKAN 730
E + + N
Sbjct: 1276 SDGERARAELN 1286
Score = 35.1 bits (77), Expect = 0.26
Identities = 27/100 (27%), Positives = 52/100 (52%), Gaps = 1/100 (1%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
++K A ++K+K + +K D+ EQ +AEK N V++L+++L + E
Sbjct: 1842 REKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKE----QAEKGNARVKQLKRQLEEAE 1897
Query: 248 ED-LILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQ 364
E+ +N N+ + ++L+E + A EV AL K++
Sbjct: 1898 EESQRINANR-RKLQRELDEATESNEAMGREVNALKSKLR 1936
>AY520816-1|AAS98910.1| 1979|Homo sapiens smooth muscle myosin heavy
chain isoform SM1 protein.
Length = 1979
Score = 54.4 bits (125), Expect = 4e-07
Identities = 38/200 (19%), Positives = 97/200 (48%), Gaps = 5/200 (2%)
Frame = +2
Query: 95 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 274
++ ++ ++ E + + + R A +AE+++ E+ ++ AQ E + +
Sbjct: 1741 LEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELAT-ERSTAQKNESA---RQQ 1796
Query: 275 LEQANKDLEEKEKQLTAT-----EAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 439
LE+ NK+L K ++ ++ +AAL K+ Q+EE +E+ A + L + +
Sbjct: 1797 LERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDK 1856
Query: 440 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 619
E + A+Q +E+ ++ ++K+ + E+A+ +S ++ ++ EL+
Sbjct: 1857 KLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDE 1916
Query: 620 AEDRVKSGDAKISXLEXELK 679
A + ++ +++ L+ +L+
Sbjct: 1917 ATESNEAMGREVNALKSKLR 1936
Score = 49.6 bits (113), Expect = 1e-05
Identities = 38/215 (17%), Positives = 98/215 (45%), Gaps = 12/215 (5%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQA----MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKL 235
+++ A A KKK++ ++L+ D+A+ + +Q R + + E+ + +
Sbjct: 1616 RKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASR 1675
Query: 236 AQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKS-------E 394
++ N+ K + DL + ++ L A E + + +++ E+L S +
Sbjct: 1676 DEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQ 1735
Query: 395 ERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSD 574
+ + ++ + ++ +E + + +R ++ ++ +QL+N+L R A+ +
Sbjct: 1736 DEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQ 1795
Query: 575 EVSRKLAFVEDELEVAEDRVKSG-DAKISXLEXEL 676
++ R+ + +L E VKS + I+ LE ++
Sbjct: 1796 QLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKI 1830
Score = 47.2 bits (107), Expect = 6e-05
Identities = 50/219 (22%), Positives = 96/219 (43%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
++ A D ++K + + ++ + Q + NL E++ E EL + ++
Sbjct: 859 EEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAET-ELYAEAEEMR 917
Query: 248 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 427
L K +LE+ ++E + ++ ++ A +K+ Q DLE+ E A+QKL
Sbjct: 918 VRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQ 977
Query: 428 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 607
+ +A+ K LE+ MD N+L + R L E+ + +++ LA E+
Sbjct: 978 LEKVTAEAK---IKKLEDEILV----MDDQNNKLSKERKLLEE---RISDLTTNLAEEEE 1027
Query: 608 ELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXK 724
+ + ++ IS LE LK S + LE + K
Sbjct: 1028 KAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRK 1066
Score = 46.4 bits (105), Expect = 1e-04
Identities = 37/185 (20%), Positives = 81/185 (43%), Gaps = 1/185 (0%)
Frame = +2
Query: 95 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 274
++++ +++ + D M+ E+ N++ +++++ + +EE + +
Sbjct: 1348 LEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKE 1407
Query: 275 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ-SADE 451
+E + EEK E L +++ + DL+ + ++K + Q A+E
Sbjct: 1408 IENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEE 1467
Query: 452 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDR 631
N K + R + + E ++ T L AR L E + K +E+ R ++ E+ ED
Sbjct: 1468 KNISSKYADERDRAEAEAREKETKALSLARALEEALEAK-EELERTNKMLKAEM---EDL 1523
Query: 632 VKSGD 646
V S D
Sbjct: 1524 VSSKD 1528
Score = 43.6 bits (98), Expect = 7e-04
Identities = 46/223 (20%), Positives = 101/223 (45%), Gaps = 9/223 (4%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEK--DNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQ 241
++ A +A +K+ +A+ L + + A++ + E+ + E + ++ K + +
Sbjct: 1477 ERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHE 1536
Query: 242 VEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQ----QIEEDLEKSEERSGT 409
+E+ + ++E+ LEE E +L ATE L +Q Q E DL+ +E++
Sbjct: 1537 LEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEE 1596
Query: 410 AQQKL---LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEV 580
+++L L ++ E+ R + L A++ +L LK+ L A+ A +E
Sbjct: 1597 KRRQLQRQLHEYETELEDERKQRALAAAAKK------KLEGDLKDLELQADSAIKGREEA 1650
Query: 581 SRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLE 709
++L ++ +++ + ++ A + K KSLE
Sbjct: 1651 IKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLE 1693
Score = 41.1 bits (92), Expect = 0.004
Identities = 33/191 (17%), Positives = 82/191 (42%), Gaps = 1/191 (0%)
Frame = +2
Query: 161 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 340
E++ + A R + + KK+ ++E + + L+ + EKQ E+
Sbjct: 1096 EEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEEL 1155
Query: 341 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKV-LENRAQQDEERMDQL 517
AL +++ + +E +Q++ +++ DE R + ++ Q+ + +++L
Sbjct: 1156 EALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEEL 1215
Query: 518 TNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSL 697
T QL++ + + D + ++ A + EL V + + K LE +++ + +
Sbjct: 1216 TEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKC 1275
Query: 698 KSLEVSEXKAN 730
E + + N
Sbjct: 1276 SDGERARAELN 1286
Score = 38.7 bits (86), Expect = 0.021
Identities = 33/129 (25%), Positives = 65/129 (50%), Gaps = 1/129 (0%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
++K A ++K+K + +K D+ EQ +AEK N V++L+++L + E
Sbjct: 1842 REKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKE----QAEKGNARVKQLKRQLEEAE 1897
Query: 248 ED-LILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL 424
E+ +N N+ + ++L+E + A EV AL K+++ E RSG +++
Sbjct: 1898 EESQRINANR-RKLQRELDEATESNEAMGREVNALKSKLRRGNETSFVPSRRSG--GRRV 1954
Query: 425 LEAQQSADE 451
+E ++E
Sbjct: 1955 IENADGSEE 1963
>AF020091-1|AAB69327.1| 622|Homo sapiens smooth muscle myosin heavy
chain SM1 protein.
Length = 622
Score = 54.4 bits (125), Expect = 4e-07
Identities = 38/200 (19%), Positives = 97/200 (48%), Gaps = 5/200 (2%)
Frame = +2
Query: 95 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 274
++ ++ ++ E + + + R A +AE+++ E+ ++ AQ E + +
Sbjct: 384 LEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELAT-ERSTAQKNESA---RQQ 439
Query: 275 LEQANKDLEEKEKQLTAT-----EAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 439
LE+ NK+L K ++ ++ +AAL K+ Q+EE +E+ A + L + +
Sbjct: 440 LERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDK 499
Query: 440 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 619
E + A+Q +E+ ++ ++K+ + E+A+ +S ++ ++ EL+
Sbjct: 500 KLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDE 559
Query: 620 AEDRVKSGDAKISXLEXELK 679
A + ++ +++ L+ +L+
Sbjct: 560 ATESNEAMGREVNALKSKLR 579
Score = 48.0 bits (109), Expect = 3e-05
Identities = 37/215 (17%), Positives = 97/215 (45%), Gaps = 12/215 (5%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQA----MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKL 235
+++ A A KKK++ ++L+ D+A+ + + R + + E+ + +
Sbjct: 259 RKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKHVRKLQAQMKDFQRELEDARASR 318
Query: 236 AQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKS-------E 394
++ N+ K + DL + ++ L A E + + +++ E+L S +
Sbjct: 319 DEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQ 378
Query: 395 ERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSD 574
+ + ++ + ++ +E + + +R ++ ++ +QL+N+L R A+ +
Sbjct: 379 DEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQ 438
Query: 575 EVSRKLAFVEDELEVAEDRVKSG-DAKISXLEXEL 676
++ R+ + +L E VKS + I+ LE ++
Sbjct: 439 QLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKI 473
Score = 42.7 bits (96), Expect = 0.001
Identities = 36/170 (21%), Positives = 72/170 (42%), Gaps = 1/170 (0%)
Frame = +2
Query: 140 MDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQL 319
M+ E+ N++ +++++ + +EE + ++E + EEK
Sbjct: 6 MEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAY 65
Query: 320 TATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ-SADENNRMCKVLENRAQQD 496
E L +++ + DL+ + ++K + Q A+E N K + R + +
Sbjct: 66 DKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAE 125
Query: 497 EERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGD 646
E ++ T L AR L E + K +E+ R ++ E+ ED V S D
Sbjct: 126 AEAREKETKALSLARALEEALEAK-EELERTNKMLKAEM---EDLVSSKD 171
Score = 41.9 bits (94), Expect = 0.002
Identities = 49/238 (20%), Positives = 104/238 (43%), Gaps = 17/238 (7%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEK--DNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQ 241
++ A +A +K+ +A+ L + + A++ + E+ + E + ++ K + +
Sbjct: 120 ERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHE 179
Query: 242 VEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQ----QIEEDL----EKSEE 397
+E+ + ++E+ LEE E +L ATE L +Q Q E DL E++EE
Sbjct: 180 LEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEE 239
Query: 398 RSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDE 577
+ Q++L E + ++ + + ++ E + L Q A E+A +
Sbjct: 240 KRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKHVRK 299
Query: 578 VSRKLAFVEDELE---VAEDRV----KSGDAKISXLEXELKVVGNSLKSLEVSEXKAN 730
+ ++ + ELE + D + K + K LE +L + L + E + +A+
Sbjct: 300 LQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQAD 357
Score = 38.7 bits (86), Expect = 0.021
Identities = 33/129 (25%), Positives = 65/129 (50%), Gaps = 1/129 (0%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
++K A ++K+K + +K D+ EQ +AEK N V++L+++L + E
Sbjct: 485 REKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKE----QAEKGNARVKQLKRQLEEAE 540
Query: 248 ED-LILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL 424
E+ +N N+ + ++L+E + A EV AL K+++ E RSG +++
Sbjct: 541 EESQRINANR-RKLQRELDEATESNEAMGREVNALKSKLRRGNETSFVPSRRSG--GRRV 597
Query: 425 LEAQQSADE 451
+E ++E
Sbjct: 598 IENADGSEE 606
>AF013570-1|AAB69326.1| 588|Homo sapiens smooth muscle myosin heavy
chain SM2 protein.
Length = 588
Score = 54.4 bits (125), Expect = 4e-07
Identities = 38/200 (19%), Positives = 97/200 (48%), Gaps = 5/200 (2%)
Frame = +2
Query: 95 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 274
++ ++ ++ E + + + R A +AE+++ E+ ++ AQ E + +
Sbjct: 384 LEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELAT-ERSTAQKNESA---RQQ 439
Query: 275 LEQANKDLEEKEKQLTAT-----EAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 439
LE+ NK+L K ++ ++ +AAL K+ Q+EE +E+ A + L + +
Sbjct: 440 LERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDK 499
Query: 440 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 619
E + A+Q +E+ ++ ++K+ + E+A+ +S ++ ++ EL+
Sbjct: 500 KLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDE 559
Query: 620 AEDRVKSGDAKISXLEXELK 679
A + ++ +++ L+ +L+
Sbjct: 560 ATESNEAMGREVNALKSKLR 579
Score = 48.0 bits (109), Expect = 3e-05
Identities = 37/215 (17%), Positives = 97/215 (45%), Gaps = 12/215 (5%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQA----MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKL 235
+++ A A KKK++ ++L+ D+A+ + + R + + E+ + +
Sbjct: 259 RKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKHVRKLQAQMKDFQRELEDARASR 318
Query: 236 AQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKS-------E 394
++ N+ K + DL + ++ L A E + + +++ E+L S +
Sbjct: 319 DEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQ 378
Query: 395 ERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSD 574
+ + ++ + ++ +E + + +R ++ ++ +QL+N+L R A+ +
Sbjct: 379 DEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQ 438
Query: 575 EVSRKLAFVEDELEVAEDRVKSG-DAKISXLEXEL 676
++ R+ + +L E VKS + I+ LE ++
Sbjct: 439 QLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKI 473
Score = 42.7 bits (96), Expect = 0.001
Identities = 36/170 (21%), Positives = 72/170 (42%), Gaps = 1/170 (0%)
Frame = +2
Query: 140 MDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQL 319
M+ E+ N++ +++++ + +EE + ++E + EEK
Sbjct: 6 MEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAY 65
Query: 320 TATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ-SADENNRMCKVLENRAQQD 496
E L +++ + DL+ + ++K + Q A+E N K + R + +
Sbjct: 66 DKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAE 125
Query: 497 EERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGD 646
E ++ T L AR L E + K +E+ R ++ E+ ED V S D
Sbjct: 126 AEAREKETKALSLARALEEALEAK-EELERTNKMLKAEM---EDLVSSKD 171
Score = 41.9 bits (94), Expect = 0.002
Identities = 49/238 (20%), Positives = 104/238 (43%), Gaps = 17/238 (7%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEK--DNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQ 241
++ A +A +K+ +A+ L + + A++ + E+ + E + ++ K + +
Sbjct: 120 ERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHE 179
Query: 242 VEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQ----QIEEDL----EKSEE 397
+E+ + ++E+ LEE E +L ATE L +Q Q E DL E++EE
Sbjct: 180 LEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEE 239
Query: 398 RSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDE 577
+ Q++L E + ++ + + ++ E + L Q A E+A +
Sbjct: 240 KRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKHVRK 299
Query: 578 VSRKLAFVEDELE---VAEDRV----KSGDAKISXLEXELKVVGNSLKSLEVSEXKAN 730
+ ++ + ELE + D + K + K LE +L + L + E + +A+
Sbjct: 300 LQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQAD 357
Score = 35.1 bits (77), Expect = 0.26
Identities = 27/100 (27%), Positives = 52/100 (52%), Gaps = 1/100 (1%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
++K A ++K+K + +K D+ EQ +AEK N V++L+++L + E
Sbjct: 485 REKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKE----QAEKGNARVKQLKRQLEEAE 540
Query: 248 ED-LILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQ 364
E+ +N N+ + ++L+E + A EV AL K++
Sbjct: 541 EESQRINANR-RKLQRELDEATESNEAMGREVNALKSKLR 579
>AF001548-1|AAC31665.1| 1857|Homo sapiens Myosin heavy chain (MHY11)
(5'partial) protein.
Length = 1857
Score = 54.4 bits (125), Expect = 4e-07
Identities = 38/200 (19%), Positives = 97/200 (48%), Gaps = 5/200 (2%)
Frame = +2
Query: 95 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 274
++ ++ ++ E + + + R A +AE+++ E+ ++ AQ E + +
Sbjct: 1619 LEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELAT-ERSTAQKNESA---RQQ 1674
Query: 275 LEQANKDLEEKEKQLTAT-----EAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 439
LE+ NK+L K ++ ++ +AAL K+ Q+EE +E+ A + L + +
Sbjct: 1675 LERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDK 1734
Query: 440 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 619
E + A+Q +E+ ++ ++K+ + E+A+ +S ++ ++ EL+
Sbjct: 1735 KLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDE 1794
Query: 620 AEDRVKSGDAKISXLEXELK 679
A + ++ +++ L+ +L+
Sbjct: 1795 ATESNEAMGREVNALKSKLR 1814
Score = 49.6 bits (113), Expect = 1e-05
Identities = 38/215 (17%), Positives = 98/215 (45%), Gaps = 12/215 (5%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQA----MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKL 235
+++ A A KKK++ ++L+ D+A+ + +Q R + + E+ + +
Sbjct: 1494 RKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASR 1553
Query: 236 AQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKS-------E 394
++ N+ K + DL + ++ L A E + + +++ E+L S +
Sbjct: 1554 DEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQ 1613
Query: 395 ERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSD 574
+ + ++ + ++ +E + + +R ++ ++ +QL+N+L R A+ +
Sbjct: 1614 DEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQ 1673
Query: 575 EVSRKLAFVEDELEVAEDRVKSG-DAKISXLEXEL 676
++ R+ + +L E VKS + I+ LE ++
Sbjct: 1674 QLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKI 1708
Score = 47.2 bits (107), Expect = 6e-05
Identities = 50/219 (22%), Positives = 96/219 (43%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
++ A D ++K + + ++ + Q + NL E++ E EL + ++
Sbjct: 737 EEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAET-ELYAEAEEMR 795
Query: 248 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 427
L K +LE+ ++E + ++ ++ A +K+ Q DLE+ E A+QKL
Sbjct: 796 VRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQ 855
Query: 428 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 607
+ +A+ K LE+ MD N+L + R L E+ + +++ LA E+
Sbjct: 856 LEKVTAEAK---IKKLEDEILV----MDDQNNKLSKERKLLEE---RISDLTTNLAEEEE 905
Query: 608 ELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXK 724
+ + ++ IS LE LK S + LE + K
Sbjct: 906 KAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRK 944
Score = 46.4 bits (105), Expect = 1e-04
Identities = 37/185 (20%), Positives = 81/185 (43%), Gaps = 1/185 (0%)
Frame = +2
Query: 95 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 274
++++ +++ + D M+ E+ N++ +++++ + +EE + +
Sbjct: 1226 LEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKE 1285
Query: 275 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ-SADE 451
+E + EEK E L +++ + DL+ + ++K + Q A+E
Sbjct: 1286 IENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEE 1345
Query: 452 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDR 631
N K + R + + E ++ T L AR L E + K +E+ R ++ E+ ED
Sbjct: 1346 KNISSKYADERDRAEAEAREKETKALSLARALEEALEAK-EELERTNKMLKAEM---EDL 1401
Query: 632 VKSGD 646
V S D
Sbjct: 1402 VSSKD 1406
Score = 43.6 bits (98), Expect = 7e-04
Identities = 46/223 (20%), Positives = 101/223 (45%), Gaps = 9/223 (4%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEK--DNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQ 241
++ A +A +K+ +A+ L + + A++ + E+ + E + ++ K + +
Sbjct: 1355 ERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHE 1414
Query: 242 VEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQ----QIEEDLEKSEERSGT 409
+E+ + ++E+ LEE E +L ATE L +Q Q E DL+ +E++
Sbjct: 1415 LEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEE 1474
Query: 410 AQQKL---LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEV 580
+++L L ++ E+ R + L A++ +L LK+ L A+ A +E
Sbjct: 1475 KRRQLQRQLHEYETELEDERKQRALAAAAKK------KLEGDLKDLELQADSAIKGREEA 1528
Query: 581 SRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLE 709
++L ++ +++ + ++ A + K KSLE
Sbjct: 1529 IKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLE 1571
Score = 41.1 bits (92), Expect = 0.004
Identities = 33/191 (17%), Positives = 82/191 (42%), Gaps = 1/191 (0%)
Frame = +2
Query: 161 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 340
E++ + A R + + KK+ ++E + + L+ + EKQ E+
Sbjct: 974 EEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEEL 1033
Query: 341 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKV-LENRAQQDEERMDQL 517
AL +++ + +E +Q++ +++ DE R + ++ Q+ + +++L
Sbjct: 1034 EALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEEL 1093
Query: 518 TNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSL 697
T QL++ + + D + ++ A + EL V + + K LE +++ + +
Sbjct: 1094 TEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKC 1153
Query: 698 KSLEVSEXKAN 730
E + + N
Sbjct: 1154 SDGERARAELN 1164
Score = 38.7 bits (86), Expect = 0.021
Identities = 33/129 (25%), Positives = 65/129 (50%), Gaps = 1/129 (0%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
++K A ++K+K + +K D+ EQ +AEK N V++L+++L + E
Sbjct: 1720 REKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKE----QAEKGNARVKQLKRQLEEAE 1775
Query: 248 ED-LILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL 424
E+ +N N+ + ++L+E + A EV AL K+++ E RSG +++
Sbjct: 1776 EESQRINANR-RKLQRELDEATESNEAMGREVNALKSKLRRGNETSFVPSRRSG--GRRV 1832
Query: 425 LEAQQSADE 451
+E ++E
Sbjct: 1833 IENADGSEE 1841
>AB020673-1|BAA74889.2| 1984|Homo sapiens KIAA0866 protein protein.
Length = 1984
Score = 54.4 bits (125), Expect = 4e-07
Identities = 38/200 (19%), Positives = 97/200 (48%), Gaps = 5/200 (2%)
Frame = +2
Query: 95 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 274
++ ++ ++ E + + + R A +AE+++ E+ ++ AQ E + +
Sbjct: 1746 LEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELAT-ERSTAQKNESA---RQQ 1801
Query: 275 LEQANKDLEEKEKQLTAT-----EAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 439
LE+ NK+L K ++ ++ +AAL K+ Q+EE +E+ A + L + +
Sbjct: 1802 LERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDK 1861
Query: 440 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 619
E + A+Q +E+ ++ ++K+ + E+A+ +S ++ ++ EL+
Sbjct: 1862 KLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDE 1921
Query: 620 AEDRVKSGDAKISXLEXELK 679
A + ++ +++ L+ +L+
Sbjct: 1922 ATESNEAMGREVNALKSKLR 1941
Score = 49.6 bits (113), Expect = 1e-05
Identities = 38/215 (17%), Positives = 98/215 (45%), Gaps = 12/215 (5%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQA----MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKL 235
+++ A A KKK++ ++L+ D+A+ + +Q R + + E+ + +
Sbjct: 1621 RKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASR 1680
Query: 236 AQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKS-------E 394
++ N+ K + DL + ++ L A E + + +++ E+L S +
Sbjct: 1681 DEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQ 1740
Query: 395 ERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSD 574
+ + ++ + ++ +E + + +R ++ ++ +QL+N+L R A+ +
Sbjct: 1741 DEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQ 1800
Query: 575 EVSRKLAFVEDELEVAEDRVKSG-DAKISXLEXEL 676
++ R+ + +L E VKS + I+ LE ++
Sbjct: 1801 QLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKI 1835
Score = 47.2 bits (107), Expect = 6e-05
Identities = 50/219 (22%), Positives = 96/219 (43%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
++ A D ++K + + ++ + Q + NL E++ E EL + ++
Sbjct: 864 EEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAET-ELYAEAEEMR 922
Query: 248 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 427
L K +LE+ ++E + ++ ++ A +K+ Q DLE+ E A+QKL
Sbjct: 923 VRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQ 982
Query: 428 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 607
+ +A+ K LE+ MD N+L + R L E+ + +++ LA E+
Sbjct: 983 LEKVTAEAK---IKKLEDEILV----MDDQNNKLSKERKLLEE---RISDLTTNLAEEEE 1032
Query: 608 ELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXK 724
+ + ++ IS LE LK S + LE + K
Sbjct: 1033 KAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRK 1071
Score = 46.4 bits (105), Expect = 1e-04
Identities = 37/185 (20%), Positives = 81/185 (43%), Gaps = 1/185 (0%)
Frame = +2
Query: 95 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 274
++++ +++ + D M+ E+ N++ +++++ + +EE + +
Sbjct: 1353 LEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKE 1412
Query: 275 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ-SADE 451
+E + EEK E L +++ + DL+ + ++K + Q A+E
Sbjct: 1413 IENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEE 1472
Query: 452 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDR 631
N K + R + + E ++ T L AR L E + K +E+ R ++ E+ ED
Sbjct: 1473 KNISSKYADERDRAEAEAREKETKALSLARALEEALEAK-EELERTNKMLKAEM---EDL 1528
Query: 632 VKSGD 646
V S D
Sbjct: 1529 VSSKD 1533
Score = 43.6 bits (98), Expect = 7e-04
Identities = 46/223 (20%), Positives = 101/223 (45%), Gaps = 9/223 (4%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEK--DNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQ 241
++ A +A +K+ +A+ L + + A++ + E+ + E + ++ K + +
Sbjct: 1482 ERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHE 1541
Query: 242 VEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQ----QIEEDLEKSEERSGT 409
+E+ + ++E+ LEE E +L ATE L +Q Q E DL+ +E++
Sbjct: 1542 LEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEE 1601
Query: 410 AQQKL---LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEV 580
+++L L ++ E+ R + L A++ +L LK+ L A+ A +E
Sbjct: 1602 KRRQLQRQLHEYETELEDERKQRALAAAAKK------KLEGDLKDLELQADSAIKGREEA 1655
Query: 581 SRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLE 709
++L ++ +++ + ++ A + K KSLE
Sbjct: 1656 IKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLE 1698
Score = 41.1 bits (92), Expect = 0.004
Identities = 33/191 (17%), Positives = 82/191 (42%), Gaps = 1/191 (0%)
Frame = +2
Query: 161 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 340
E++ + A R + + KK+ ++E + + L+ + EKQ E+
Sbjct: 1101 EEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEEL 1160
Query: 341 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKV-LENRAQQDEERMDQL 517
AL +++ + +E +Q++ +++ DE R + ++ Q+ + +++L
Sbjct: 1161 EALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEEL 1220
Query: 518 TNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSL 697
T QL++ + + D + ++ A + EL V + + K LE +++ + +
Sbjct: 1221 TEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKC 1280
Query: 698 KSLEVSEXKAN 730
E + + N
Sbjct: 1281 SDGERARAELN 1291
Score = 38.7 bits (86), Expect = 0.021
Identities = 33/129 (25%), Positives = 65/129 (50%), Gaps = 1/129 (0%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
++K A ++K+K + +K D+ EQ +AEK N V++L+++L + E
Sbjct: 1847 REKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKE----QAEKGNARVKQLKRQLEEAE 1902
Query: 248 ED-LILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL 424
E+ +N N+ + ++L+E + A EV AL K+++ E RSG +++
Sbjct: 1903 EESQRINANR-RKLQRELDEATESNEAMGREVNALKSKLRRGNETSFVPSRRSG--GRRV 1959
Query: 425 LEAQQSADE 451
+E ++E
Sbjct: 1960 IENADGSEE 1968
>Z82215-4|CAB05105.1| 1960|Homo sapiens myosin, heavy chain 9,
non-muscle protein.
Length = 1960
Score = 54.0 bits (124), Expect = 5e-07
Identities = 47/189 (24%), Positives = 81/189 (42%)
Frame = +2
Query: 161 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 340
E Q +D ++ N + L KL QVE++ + +LE+ + EKQ+ A+V
Sbjct: 1307 ESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQV 1366
Query: 341 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 520
A + +K++ LE +EE Q+ L Q +E LE + ++ +D L
Sbjct: 1367 ADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLL 1426
Query: 521 NQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLK 700
L R A + + K + + LA E++ A+ + A+ E E K + +
Sbjct: 1427 VDLDHQRQSACNLEKKQKKFDQLLA--EEKTISAKYAEERDRAEAEAREKETKALSLARA 1484
Query: 701 SLEVSEXKA 727
E E KA
Sbjct: 1485 LEEAMEQKA 1493
Score = 51.2 bits (117), Expect = 4e-06
Identities = 52/221 (23%), Positives = 103/221 (46%), Gaps = 23/221 (10%)
Frame = +2
Query: 92 AIKKKMQAMK-LEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 268
A K + +A+K L K A K C ++ D E++ + +E +KKL +E ++I +
Sbjct: 1629 ANKNRDEAIKQLRKLQAQMK--DCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQ 1686
Query: 269 NKL---EQANKDLEEKEKQLTATEA-----------EVAALNRKVQQIEEDLEKSEERSG 406
+L E+A + +++ +L A E L ++ Q+EE+LE+ + +
Sbjct: 1687 EELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTE 1746
Query: 407 TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADG--KS--- 571
+L +A D+ N + + AQ++E QL Q KE ++ ++ +G KS
Sbjct: 1747 LINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYK 1806
Query: 572 ---DEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVV 685
+ K+A +E++L+ ++ ++ E +LK V
Sbjct: 1807 ASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDV 1847
Score = 45.6 bits (103), Expect = 2e-04
Identities = 45/195 (23%), Positives = 92/195 (47%), Gaps = 3/195 (1%)
Frame = +2
Query: 104 KMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDL---ILNKNK 274
KMQ K E++ A E++A N+ +K+ REL+ ++++++EDL ++NK
Sbjct: 1075 KMQLAKKEEELQAALARV-EEEAAQKNMALKKI----RELESQISELQEDLESERASRNK 1129
Query: 275 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 454
E+ +DL E E + TE E + QQ +L E+ +K LE + E
Sbjct: 1130 AEKQKRDLGE-ELEALKTELEDTLDSTAAQQ---ELRSKREQEVNILKKTLEEEAKTHE- 1184
Query: 455 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRV 634
++ E R Q+ + +++L QL++ + + + + + + + +E++V
Sbjct: 1185 ---AQIQEMR-QKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGK 1240
Query: 635 KSGDAKISXLEXELK 679
+ K +E +L+
Sbjct: 1241 GDSEHKRKKVEAQLQ 1255
Score = 43.6 bits (98), Expect = 7e-04
Identities = 49/237 (20%), Positives = 99/237 (41%), Gaps = 17/237 (7%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEK--DNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQ 241
++ A +A +K+ +A+ L + + AM++ E+ + E + ++ K + +
Sbjct: 1463 ERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHE 1522
Query: 242 VEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQ----QIEEDLEKSEERSGT 409
+E+ + ++E+ LEE E +L ATE L +Q Q E DL+ +E+S
Sbjct: 1523 LEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEE 1582
Query: 410 AQQKL------LEAQQSADENNRMC-----KVLENRAQQDEERMDQLTNQLKEARLLAED 556
+++L +EA+ + R K LE + E +D EA
Sbjct: 1583 KKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRK 1642
Query: 557 ADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXKA 727
+ + R+L E + K + K+ +E E+ + L + E ++ +A
Sbjct: 1643 LQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQA 1699
Score = 43.2 bits (97), Expect = 0.001
Identities = 32/145 (22%), Positives = 69/145 (47%), Gaps = 4/145 (2%)
Frame = +2
Query: 206 EEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEK---QLTATEAEVAA-LNRKVQQIE 373
+++ + + +L Q +DL+++ + Q+ +LE+K+K QL A E ++A + + E
Sbjct: 1409 DKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAE 1468
Query: 374 EDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAE 553
+ + E ++ + + L EA + E R+ K + D + + E
Sbjct: 1469 AEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKR 1528
Query: 554 DADGKSDEVSRKLAFVEDELEVAED 628
+ + +E+ +L +EDEL+ ED
Sbjct: 1529 ALEQQVEEMKTQLEELEDELQATED 1553
Score = 43.2 bits (97), Expect = 0.001
Identities = 46/219 (21%), Positives = 100/219 (45%), Gaps = 18/219 (8%)
Frame = +2
Query: 80 ATMDA---IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNE---EVRELQKKLA- 238
AT DA ++ +QAMK + + + D ++ + +R + E E Q+ +A
Sbjct: 1550 ATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAV 1609
Query: 239 ----QVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEK--SEER 400
++E DL + ++ ANK+ +E KQL +A++ R++ E+ ++ +
Sbjct: 1610 AARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAK 1669
Query: 401 SGTAQQKLLEAQQ-SADENNRMCKVLENRAQQD-EERMDQLTNQLKEARLLAED---ADG 565
+ K +EA+ E + + +AQQ+ +E D++ N + L E+ +
Sbjct: 1670 ENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEA 1729
Query: 566 KSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKV 682
+ ++ +L + E+ DR+K + +I + +L +
Sbjct: 1730 RIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNL 1768
Score = 39.5 bits (88), Expect = 0.012
Identities = 54/242 (22%), Positives = 109/242 (45%), Gaps = 26/242 (10%)
Frame = +2
Query: 80 ATMDAIKKKMQAMKLEKDNAMD--KADTCEQQARDANLRAEKVNEEVRELQKKLAQVEED 253
A + ++ ++ A K E + +A E++ R +L+AEK +++Q+ + ++EE
Sbjct: 897 AEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEK-----KKMQQNIQELEEQ 951
Query: 254 LILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEA 433
L ++ ++ + E +L E E L + ++ ++ + E+R L E
Sbjct: 952 LEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEE 1011
Query: 434 QQSA-------DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSR-- 586
++ + +++ M LE R +++E++ +L K R L D+ SD+++
Sbjct: 1012 EEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELE---KTRRKLEGDSTDLSDQIAELQ 1068
Query: 587 --------KLAFVEDELEVAEDRVKSGDA-------KISXLEXELKVVGNSLKSLEVSEX 721
+LA E+EL+ A RV+ A KI LE ++ + L+S S
Sbjct: 1069 AQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRN 1128
Query: 722 KA 727
KA
Sbjct: 1129 KA 1130
Score = 36.7 bits (81), Expect = 0.086
Identities = 44/220 (20%), Positives = 98/220 (44%), Gaps = 14/220 (6%)
Frame = +2
Query: 92 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN 271
++ K++ ++ EK++ ++ + E+ + + ++ +V +++KK+ L +
Sbjct: 1326 SLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEE 1385
Query: 272 KLEQANKDLE----EKEKQLTATEAEVAALNRKVQQIEE---DLEKSEERSGTAQQKLLE 430
+ KDLE E+++ A + R Q++++ DL+ + + ++K +
Sbjct: 1386 VKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKK 1445
Query: 431 AQQ-SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAF--- 598
Q A+E K E R + + E ++ T L AR L E + K++ F
Sbjct: 1446 FDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTE 1505
Query: 599 VEDELEVAEDRVKSG---DAKISXLEXELKVVGNSLKSLE 709
+ED + +D KS + LE +++ + L+ LE
Sbjct: 1506 MEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELE 1545
>X52889-1|CAA37068.1| 1934|Homo sapiens cardiac beta myosin heavy
chain protein.
Length = 1934
Score = 54.0 bits (124), Expect = 5e-07
Identities = 44/202 (21%), Positives = 88/202 (43%), Gaps = 12/202 (5%)
Frame = +2
Query: 161 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 340
+ + D + E+ N L KK ++ L K K E++ +LE +K+ + E+
Sbjct: 1422 QNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTEL 1481
Query: 341 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 520
L ++ E LE + + Q+++ + + + + LE +Q E +L
Sbjct: 1482 FKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQ 1541
Query: 521 NQLKEARLLAEDADGK-----------SDEVSRKLAFVEDELEVAE-DRVKSGDAKISXL 664
+ L+EA E +GK E+ RKLA ++E+E A+ + ++ D+ + L
Sbjct: 1542 SALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSL 1601
Query: 665 EXELKVVGNSLKSLEVSEXKAN 730
+ E + +L+ + E N
Sbjct: 1602 DAETRSRNEALRVKKKMEGDLN 1623
Score = 51.6 bits (118), Expect = 3e-06
Identities = 51/211 (24%), Positives = 100/211 (47%), Gaps = 18/211 (8%)
Frame = +2
Query: 98 KKKMQA-MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLI-LNK- 268
+++M A + +K N D+ ++ D L KV +E + K+ + E++ L++
Sbjct: 929 EEEMNAELTAKKRNVEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEI 988
Query: 269 -NKLEQANKDLEEKEKQ----LTATEAEVAALNR---KVQQIEEDLEKSEERSGTAQQKL 424
KL + K L+E +Q L A E +V L + K++Q +DLE S E+ + L
Sbjct: 989 IAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDL 1048
Query: 425 LEAQQSADENNRMCKV----LENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKL 592
A++ + + ++ + LEN QQ +ER+ + +L ED ++ +KL
Sbjct: 1049 ERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKL 1108
Query: 593 AFVEDELEVAEDRV---KSGDAKISXLEXEL 676
++ +E E+ + ++ AK+ L +L
Sbjct: 1109 KELQARIEELEEELEAERTARAKVEKLRSDL 1139
Score = 51.6 bits (118), Expect = 3e-06
Identities = 54/227 (23%), Positives = 103/227 (45%), Gaps = 15/227 (6%)
Frame = +2
Query: 95 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEE---DLILN 265
++K+ KLE D+ + + + + +++ E + K + + DL
Sbjct: 1217 LEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQ 1276
Query: 266 KNKLEQANKDLEEKEKQLTATEAEVAALNR----KVQQIEEDLEKSEERSGTAQQKLLEA 433
+ KL+ N +L +QL EA ++ L R QQ+ EDL++ E A+ L A
Sbjct: 1277 RAKLQTENGEL---SRQLDEKEALISQLTRGKLTYTQQL-EDLKRQLEEEVKAKNALAHA 1332
Query: 434 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL-LAE-------DADGKSDEVSRK 589
QSA + C +L + +++ E +L L +A +A+ DA +++E+
Sbjct: 1333 LQSARHD---CDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEA 1389
Query: 590 LAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXKAN 730
+ L+ AE+ V++ +AK S LE + N ++ L V ++N
Sbjct: 1390 KKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSN 1436
Score = 50.8 bits (116), Expect = 5e-06
Identities = 57/239 (23%), Positives = 114/239 (47%), Gaps = 25/239 (10%)
Frame = +2
Query: 86 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAE-KVNEEVRELQKKLAQVEEDLIL 262
++ ++K+++A K+E +A+++A+ + LRA+ + N+ E+++KLA+ +E+
Sbjct: 1526 LEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEE--- 1582
Query: 263 NKNKLEQANKD-LEEKEKQLTATEAEVAALN---RKVQQIEEDLEKSEERSGTAQQKLLE 430
+EQA ++ L + T+ +AE + N R +++E DL + E + A + E
Sbjct: 1583 ----MEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAE 1638
Query: 431 AQQSADENNRMCK----VLEN--RAQQD-------EERMDQLTNQLKEARLLAED----- 556
AQ+ + K L++ RA D ER + L +L+E R + E
Sbjct: 1639 AQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLQAELEELRAVVEQTERSR 1698
Query: 557 --ADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXKA 727
AD + E S ++ + + ++ K DA +S L+ E++ ++ E KA
Sbjct: 1699 KLADRELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKA 1757
Score = 50.0 bits (114), Expect = 9e-06
Identities = 53/221 (23%), Positives = 98/221 (44%), Gaps = 7/221 (3%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
+++ +A+ +Q+ + + D ++ + + + K N EV + + K E
Sbjct: 1320 EEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKY---E 1376
Query: 248 EDLILNKNKLEQANKDL----EEKEKQLTATEAEVAALNRKVQQIE---EDLEKSEERSG 406
D I +LE+A K L +E E+ + A A+ ++L + +++ EDL ERS
Sbjct: 1377 TDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSN 1436
Query: 407 TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSR 586
A L + Q++ D K+L Q+ EE +L + KEAR L+ + +
Sbjct: 1437 AAAAALDKKQRNFD------KILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEE 1490
Query: 587 KLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLE 709
L + LE + K+ +IS L +L G ++ LE
Sbjct: 1491 SL----EHLETFKRENKNLQEEISDLTEQLGSSGKTIHELE 1527
Score = 49.6 bits (113), Expect = 1e-05
Identities = 49/223 (21%), Positives = 102/223 (45%), Gaps = 19/223 (8%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQA-MKLEKDNAMDKADTCEQ----------QARDANLRAEKVNEEV 214
++K ++ K +Q ++ E+DN D + C+Q + ++ N R E E
Sbjct: 874 EEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMN 933
Query: 215 RELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEK-S 391
EL K VE++ K ++ L + EK+ ATE +V L ++ ++E + K +
Sbjct: 934 AELTAKKRNVEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLT 993
Query: 392 EERSG---TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDA- 559
+E+ QQ L + Q D+ N + K + + +Q + ++ Q K+ R+ E A
Sbjct: 994 KEKKALQEAHQQALDDLQAEEDKVNTLTKA-KVKLEQQVDDLEGSLEQEKKVRMDLERAK 1052
Query: 560 ---DGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELK 679
+G + +E++ + ++R+K D +++ L ++
Sbjct: 1053 RKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIE 1095
Score = 46.4 bits (105), Expect = 1e-04
Identities = 33/153 (21%), Positives = 72/153 (47%)
Frame = +2
Query: 164 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 343
QQA D +L+AE+ ++V L K ++E+ + + LEQ K + E+ E ++
Sbjct: 1004 QQALD-DLQAEE--DKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLK 1060
Query: 344 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 523
+ +E D ++ +ER +L ++ + L+ + ++ + R+++L
Sbjct: 1061 LTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEE 1120
Query: 524 QLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 622
+L+ R + ++SR+L + + LE A
Sbjct: 1121 ELEAERTARAKVEKLRSDLSRELEEISERLEEA 1153
Score = 44.8 bits (101), Expect = 3e-04
Identities = 36/142 (25%), Positives = 65/142 (45%), Gaps = 7/142 (4%)
Frame = +2
Query: 302 EKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLEN 481
E+EK++ + + E AL +E LEKSE R ++K++ Q ++ + ++
Sbjct: 844 EREKEMASMKEEFTAL-------KEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQD 896
Query: 482 RAQQDEERMDQLTN-------QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKS 640
EER DQL ++KE ED + + E++ K VEDE + +
Sbjct: 897 NLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRNVEDECSELKRDIDD 956
Query: 641 GDAKISXLEXELKVVGNSLKSL 706
+ ++ +E E N +K+L
Sbjct: 957 LELTLAKVEKEKHATENKVKNL 978
Score = 35.5 bits (78), Expect = 0.20
Identities = 41/204 (20%), Positives = 94/204 (46%), Gaps = 13/204 (6%)
Frame = +2
Query: 92 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEV-RELQKKLAQVEE------ 250
A+ ++Q E +++ + + R A + EK+ ++ REL++ ++EE
Sbjct: 1099 ALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATS 1158
Query: 251 -DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRK----VQQIEEDLEKSEERSGTAQ 415
+ +NK + + K + E+ EA AAL +K V ++ E ++ + +
Sbjct: 1159 CQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLE 1218
Query: 416 QKLLEAQQSADE-NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKL 592
++ E + D+ + M ++++ +A E+ L +Q+ E R AE+ ++++ +
Sbjct: 1219 KEKSEFKLELDDVTSNMEQIIKAKANL-EKMCRTLEDQMNEHRSKAEETQRSVNDLTSQR 1277
Query: 593 AFVEDELEVAEDRVKSGDAKISXL 664
A ++ E ++ +A IS L
Sbjct: 1278 AKLQTENGELSRQLDEKEALISQL 1301
>X51591-1|CAA35940.1| 1151|Homo sapiens beta-myosin heavy chain (1151
AA) protein.
Length = 1151
Score = 54.0 bits (124), Expect = 5e-07
Identities = 44/202 (21%), Positives = 88/202 (43%), Gaps = 12/202 (5%)
Frame = +2
Query: 161 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 340
+ + D + E+ N L KK ++ L K K E++ +LE +K+ + E+
Sbjct: 638 QNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTEL 697
Query: 341 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 520
L ++ E LE + + Q+++ + + + + LE +Q E +L
Sbjct: 698 FKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQ 757
Query: 521 NQLKEARLLAEDADGK-----------SDEVSRKLAFVEDELEVAE-DRVKSGDAKISXL 664
+ L+EA E +GK E+ RKLA ++E+E A+ + ++ D+ + L
Sbjct: 758 SALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSL 817
Query: 665 EXELKVVGNSLKSLEVSEXKAN 730
+ E + +L+ + E N
Sbjct: 818 DAETRSRNEALRVKKKMEGDLN 839
Score = 51.6 bits (118), Expect = 3e-06
Identities = 54/227 (23%), Positives = 103/227 (45%), Gaps = 15/227 (6%)
Frame = +2
Query: 95 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEE---DLILN 265
++K+ KLE D+ + + + + +++ E + K + + DL
Sbjct: 433 LEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQ 492
Query: 266 KNKLEQANKDLEEKEKQLTATEAEVAALNR----KVQQIEEDLEKSEERSGTAQQKLLEA 433
+ KL+ N +L +QL EA ++ L R QQ+ EDL++ E A+ L A
Sbjct: 493 RAKLQTENGEL---SRQLDEKEALISQLTRGKLTYTQQL-EDLKRQLEEEVKAKNALAHA 548
Query: 434 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL-LAE-------DADGKSDEVSRK 589
QSA + C +L + +++ E +L L +A +A+ DA +++E+
Sbjct: 549 LQSARHD---CDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEA 605
Query: 590 LAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXKAN 730
+ L+ AE+ V++ +AK S LE + N ++ L V ++N
Sbjct: 606 KKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSN 652
Score = 51.2 bits (117), Expect = 4e-06
Identities = 54/228 (23%), Positives = 113/228 (49%), Gaps = 14/228 (6%)
Frame = +2
Query: 86 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAE-KVNEEVRELQKKLAQVEEDLIL 262
++ ++K+++A K+E +A+++A+ + LRA+ + N+ E+++KLA+ +E+
Sbjct: 742 LEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEE--- 798
Query: 263 NKNKLEQANKD-LEEKEKQLTATEAEVAALN---RKVQQIEEDLEKSEERSGTAQQKLLE 430
+EQA ++ L + T+ +AE + N R +++E DL + E + A + E
Sbjct: 799 ----MEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAE 854
Query: 431 AQQSADENNRMCK----VLENRAQQDEERMDQLT-----NQLKEARLLAEDADGKSDEVS 583
AQ+ + K L++ + +++ + + N L +A L A + E S
Sbjct: 855 AQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERS 914
Query: 584 RKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXKA 727
RKLA ++EL +RV+ ++ + L + K + L L+ +A
Sbjct: 915 RKLA--DEELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEA 960
Score = 50.4 bits (115), Expect = 7e-06
Identities = 49/215 (22%), Positives = 104/215 (48%), Gaps = 12/215 (5%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQ----AMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKL 235
++ A + A K+K++ +K + D+ E++ + + + EE+ L + +
Sbjct: 146 EEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEII 205
Query: 236 AQVEEDLILNKNKLEQANKDLE-EKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTA 412
A++ ++ + +QA DL+ E++K T T+A+V K++Q +DLE S E+
Sbjct: 206 AKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKV-----KLEQQVDDLEGSLEQEKKV 260
Query: 413 QQKLLEAQQSADENNRMCKV----LENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEV 580
+ L A++ + + ++ + LEN QQ EER+ + +L ED ++
Sbjct: 261 RMDLERAKRKLEGDLKLTQESIMDLENDKQQLEERLKKKDFELNALNARIEDEQALGSQL 320
Query: 581 SRKLAFVEDELEVAEDRV---KSGDAKISXLEXEL 676
+KL ++ +E E+ + ++ AK+ L +L
Sbjct: 321 QKKLKELQARIEELEEELEAERTARAKVEKLRSDL 355
Score = 50.0 bits (114), Expect = 9e-06
Identities = 49/223 (21%), Positives = 103/223 (46%), Gaps = 19/223 (8%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQA-MKLEKDNAMDKADTCEQ----------QARDANLRAEKVNEEV 214
++K ++ K +Q ++ E+DN D + C+Q + ++ N R E E
Sbjct: 90 EEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMN 149
Query: 215 RELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEK-S 391
EL K ++E++ K ++ L + EK+ ATE +V L ++ ++E + K +
Sbjct: 150 AELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLT 209
Query: 392 EERSG---TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDA- 559
+E+ QQ L + Q D+ N + K + + +Q + ++ Q K+ R+ E A
Sbjct: 210 KEKKALQEAHQQALDDLQAEEDKVNTLTKA-KVKLEQQVDDLEGSLEQEKKVRMDLERAK 268
Query: 560 ---DGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELK 679
+G + +E++ + E+R+K D +++ L ++
Sbjct: 269 RKLEGDLKLTQESIMDLENDKQQLEERLKKKDFELNALNARIE 311
Score = 50.0 bits (114), Expect = 9e-06
Identities = 53/221 (23%), Positives = 98/221 (44%), Gaps = 7/221 (3%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
+++ +A+ +Q+ + + D ++ + + + K N EV + + K E
Sbjct: 536 EEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKY---E 592
Query: 248 EDLILNKNKLEQANKDL----EEKEKQLTATEAEVAALNRKVQQIE---EDLEKSEERSG 406
D I +LE+A K L +E E+ + A A+ ++L + +++ EDL ERS
Sbjct: 593 TDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSN 652
Query: 407 TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSR 586
A L + Q++ D K+L Q+ EE +L + KEAR L+ + +
Sbjct: 653 AAAAALDKKQRNFD------KILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEE 706
Query: 587 KLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLE 709
L + LE + K+ +IS L +L G ++ LE
Sbjct: 707 SL----EHLETFKRENKNLQEEISDLTEQLGSSGKTIHELE 743
Score = 47.6 bits (108), Expect = 5e-05
Identities = 34/153 (22%), Positives = 72/153 (47%)
Frame = +2
Query: 164 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 343
QQA D +L+AE+ ++V L K ++E+ + + LEQ K + E+ E ++
Sbjct: 220 QQALD-DLQAEE--DKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLK 276
Query: 344 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 523
+ +E D ++ EER +L ++ + L+ + ++ + R+++L
Sbjct: 277 LTQESIMDLENDKQQLEERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEE 336
Query: 524 QLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 622
+L+ R + ++SR+L + + LE A
Sbjct: 337 ELEAERTARAKVEKLRSDLSRELEEISERLEEA 369
Score = 42.3 bits (95), Expect = 0.002
Identities = 33/142 (23%), Positives = 66/142 (46%), Gaps = 7/142 (4%)
Frame = +2
Query: 302 EKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLEN 481
E+EK++ A++ + +++E LEKSE R ++K++ Q ++ + ++
Sbjct: 60 EREKEM-------ASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQD 112
Query: 482 RAQQDEERMDQLTN-------QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKS 640
EER DQL ++KE ED + + E++ K +EDE + +
Sbjct: 113 NLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDD 172
Query: 641 GDAKISXLEXELKVVGNSLKSL 706
+ ++ +E E N +K+L
Sbjct: 173 LELTLAKVEKEKHATENKVKNL 194
Score = 35.5 bits (78), Expect = 0.20
Identities = 41/204 (20%), Positives = 94/204 (46%), Gaps = 13/204 (6%)
Frame = +2
Query: 92 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEV-RELQKKLAQVEE------ 250
A+ ++Q E +++ + + R A + EK+ ++ REL++ ++EE
Sbjct: 315 ALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATS 374
Query: 251 -DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRK----VQQIEEDLEKSEERSGTAQ 415
+ +NK + + K + E+ EA AAL +K V ++ E ++ + +
Sbjct: 375 VQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLE 434
Query: 416 QKLLEAQQSADE-NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKL 592
++ E + D+ + M ++++ +A E+ L +Q+ E R AE+ ++++ +
Sbjct: 435 KEKSEFKLELDDVTSNMEQIIKAKANL-EKMCRTLEDQMNEHRSKAEETQRSVNDLTSQR 493
Query: 593 AFVEDELEVAEDRVKSGDAKISXL 664
A ++ E ++ +A IS L
Sbjct: 494 AKLQTENGELSRQLDEKEALISQL 517
>X06976-1|CAA30039.1| 543|Homo sapiens beta myosin heavy chain (
544 AA) protein.
Length = 543
Score = 54.0 bits (124), Expect = 5e-07
Identities = 44/202 (21%), Positives = 88/202 (43%), Gaps = 12/202 (5%)
Frame = +2
Query: 161 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 340
+ + D + E+ N L KK ++ L K K E++ +LE +K+ + E+
Sbjct: 30 QNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTEL 89
Query: 341 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 520
L ++ E LE + + Q+++ + + + + LE +Q E +L
Sbjct: 90 FKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQ 149
Query: 521 NQLKEARLLAEDADGK-----------SDEVSRKLAFVEDELEVAE-DRVKSGDAKISXL 664
+ L+EA E +GK E+ RKLA ++E+E A+ + ++ D+ + L
Sbjct: 150 SALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSL 209
Query: 665 EXELKVVGNSLKSLEVSEXKAN 730
+ E + +L+ + E N
Sbjct: 210 DAETRSRNEALRVKKKMEGDLN 231
Score = 50.4 bits (115), Expect = 7e-06
Identities = 45/233 (19%), Positives = 109/233 (46%), Gaps = 19/233 (8%)
Frame = +2
Query: 86 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAE-KVNEEVRELQKKLAQVEEDL-I 259
++ ++K+++A K+E +A+++A+ + LRA+ + N+ E+++KLA+ +E++
Sbjct: 134 LEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQ 193
Query: 260 LNKNKLE-----QANKDLEEK------------EKQLTATEAEVAALNRKVQQIEEDLEK 388
+N L Q + D E + E L E +++ NR + ++ ++
Sbjct: 194 AKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKS 253
Query: 389 SEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGK 568
+ Q +L +A ++ D+ ++E R + +++L +++ + AD +
Sbjct: 254 LQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLADRE 313
Query: 569 SDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXKA 727
E S ++ + + ++ K DA +S L+ E++ ++ E KA
Sbjct: 314 LIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKA 366
Score = 39.9 bits (89), Expect = 0.009
Identities = 38/141 (26%), Positives = 65/141 (46%), Gaps = 3/141 (2%)
Frame = +2
Query: 296 LEEKEKQLTATEAEVAALNRKVQQIE---EDLEKSEERSGTAQQKLLEAQQSADENNRMC 466
L+E E+ + A A+ ++L + +++ EDL ERS A L + Q++ D
Sbjct: 5 LQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFD------ 58
Query: 467 KVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGD 646
K+L Q+ EE +L + KEAR L+ + + L + LE + K+
Sbjct: 59 KILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESL----EHLETFKRENKNLQ 114
Query: 647 AKISXLEXELKVVGNSLKSLE 709
+IS L +L G ++ LE
Sbjct: 115 EEISDLTEQLGSSGKTIHELE 135
>M58018-1|AAA62830.1| 1935|Homo sapiens beta-myosin heavy chain
protein.
Length = 1935
Score = 54.0 bits (124), Expect = 5e-07
Identities = 44/202 (21%), Positives = 88/202 (43%), Gaps = 12/202 (5%)
Frame = +2
Query: 161 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 340
+ + D + E+ N L KK ++ L K K E++ +LE +K+ + E+
Sbjct: 1422 QNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTEL 1481
Query: 341 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 520
L ++ E LE + + Q+++ + + + + LE +Q E +L
Sbjct: 1482 FKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQ 1541
Query: 521 NQLKEARLLAEDADGK-----------SDEVSRKLAFVEDELEVAE-DRVKSGDAKISXL 664
+ L+EA E +GK E+ RKLA ++E+E A+ + ++ D+ + L
Sbjct: 1542 SALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSL 1601
Query: 665 EXELKVVGNSLKSLEVSEXKAN 730
+ E + +L+ + E N
Sbjct: 1602 DAETRSRNEALRVKKKMEGDLN 1623
Score = 51.6 bits (118), Expect = 3e-06
Identities = 54/227 (23%), Positives = 103/227 (45%), Gaps = 15/227 (6%)
Frame = +2
Query: 95 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEE---DLILN 265
++K+ KLE D+ + + + + +++ E + K + + DL
Sbjct: 1217 LEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQ 1276
Query: 266 KNKLEQANKDLEEKEKQLTATEAEVAALNR----KVQQIEEDLEKSEERSGTAQQKLLEA 433
+ KL+ N +L +QL EA ++ L R QQ+ EDL++ E A+ L A
Sbjct: 1277 RAKLQTENGEL---SRQLDEKEALISQLTRGKLTYTQQL-EDLKRQLEEEVKAKNALAHA 1332
Query: 434 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL-LAE-------DADGKSDEVSRK 589
QSA + C +L + +++ E +L L +A +A+ DA +++E+
Sbjct: 1333 LQSARHD---CDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEA 1389
Query: 590 LAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXKAN 730
+ L+ AE+ V++ +AK S LE + N ++ L V ++N
Sbjct: 1390 KKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSN 1436
Score = 51.6 bits (118), Expect = 3e-06
Identities = 55/228 (24%), Positives = 112/228 (49%), Gaps = 14/228 (6%)
Frame = +2
Query: 86 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAE-KVNEEVRELQKKLAQVEEDLIL 262
++ ++K+++A K+E +A+++A+ + LRA+ + N+ E+++KLA+ +E+
Sbjct: 1526 LEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEE--- 1582
Query: 263 NKNKLEQANKD-LEEKEKQLTATEAEVAALN---RKVQQIEEDLEKSEERSGTAQQKLLE 430
+EQA ++ L + T+ +AE + N R +++E DL + E + A + E
Sbjct: 1583 ----MEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAE 1638
Query: 431 AQQSADENNRMCK----VLENRAQQDEERMDQLT-----NQLKEARLLAEDADGKSDEVS 583
AQ+ + K L++ + +++ + + N L +A L A + E S
Sbjct: 1639 AQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERS 1698
Query: 584 RKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXKA 727
RKLA E EL +RV+ ++ + L + K + L L+ +A
Sbjct: 1699 RKLA--EQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEA 1744
Score = 50.0 bits (114), Expect = 9e-06
Identities = 49/215 (22%), Positives = 104/215 (48%), Gaps = 12/215 (5%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQ----AMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKL 235
++ A + A K+K++ +K + D+ E++ + + + EE+ L + +
Sbjct: 930 EEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEII 989
Query: 236 AQVEEDLILNKNKLEQANKDLE-EKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTA 412
A++ ++ + +QA DL+ E++K T T+A+V K++Q +DLE S E+
Sbjct: 990 AKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKV-----KLEQQVDDLEGSLEQEKKV 1044
Query: 413 QQKLLEAQQSADENNRMCKV----LENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEV 580
+ L A++ + + ++ + LEN QQ +ER+ + +L ED ++
Sbjct: 1045 RMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQL 1104
Query: 581 SRKLAFVEDELEVAEDRVKS---GDAKISXLEXEL 676
+KL ++ +E E+ ++S AK+ L +L
Sbjct: 1105 QKKLKELQARIEELEEELESERTARAKVEKLRSDL 1139
Score = 50.0 bits (114), Expect = 9e-06
Identities = 53/221 (23%), Positives = 98/221 (44%), Gaps = 7/221 (3%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
+++ +A+ +Q+ + + D ++ + + + K N EV + + K E
Sbjct: 1320 EEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKY---E 1376
Query: 248 EDLILNKNKLEQANKDL----EEKEKQLTATEAEVAALNRKVQQIE---EDLEKSEERSG 406
D I +LE+A K L +E E+ + A A+ ++L + +++ EDL ERS
Sbjct: 1377 TDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSN 1436
Query: 407 TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSR 586
A L + Q++ D K+L Q+ EE +L + KEAR L+ + +
Sbjct: 1437 AAAAALDKKQRNFD------KILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEE 1490
Query: 587 KLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLE 709
L + LE + K+ +IS L +L G ++ LE
Sbjct: 1491 SL----EHLETFKRENKNLQEEISDLTEQLGSSGKTIHELE 1527
Score = 48.8 bits (111), Expect = 2e-05
Identities = 48/223 (21%), Positives = 103/223 (46%), Gaps = 19/223 (8%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQA-MKLEKDNAMDKADTCEQ----------QARDANLRAEKVNEEV 214
++K ++ K +Q ++ E+DN D + C+Q + ++ N R E E
Sbjct: 874 EEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMN 933
Query: 215 RELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEK-S 391
EL K ++E++ K ++ L + EK+ ATE +V L ++ ++E + K +
Sbjct: 934 AELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLT 993
Query: 392 EERSG---TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDA- 559
+E+ QQ L + Q D+ N + K + + +Q + ++ Q K+ R+ E A
Sbjct: 994 KEKKALQEAHQQALDDLQAEEDKVNTLTKA-KVKLEQQVDDLEGSLEQEKKVRMDLERAK 1052
Query: 560 ---DGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELK 679
+G + +E++ + ++R+K D +++ L ++
Sbjct: 1053 RKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIE 1095
Score = 46.8 bits (106), Expect = 8e-05
Identities = 33/153 (21%), Positives = 72/153 (47%)
Frame = +2
Query: 164 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 343
QQA D +L+AE+ ++V L K ++E+ + + LEQ K + E+ E ++
Sbjct: 1004 QQALD-DLQAEE--DKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLK 1060
Query: 344 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 523
+ +E D ++ +ER +L ++ + L+ + ++ + R+++L
Sbjct: 1061 LTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEE 1120
Query: 524 QLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 622
+L+ R + ++SR+L + + LE A
Sbjct: 1121 ELESERTARAKVEKLRSDLSRELEEISERLEEA 1153
Score = 42.3 bits (95), Expect = 0.002
Identities = 33/142 (23%), Positives = 66/142 (46%), Gaps = 7/142 (4%)
Frame = +2
Query: 302 EKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLEN 481
E+EK++ A++ + +++E LEKSE R ++K++ Q ++ + ++
Sbjct: 844 EREKEM-------ASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQD 896
Query: 482 RAQQDEERMDQLTN-------QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKS 640
EER DQL ++KE ED + + E++ K +EDE + +
Sbjct: 897 NLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDD 956
Query: 641 GDAKISXLEXELKVVGNSLKSL 706
+ ++ +E E N +K+L
Sbjct: 957 LELTLAKVEKEKHATENKVKNL 978
Score = 35.9 bits (79), Expect = 0.15
Identities = 41/204 (20%), Positives = 94/204 (46%), Gaps = 13/204 (6%)
Frame = +2
Query: 92 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEV-RELQKKLAQVEE------ 250
A+ ++Q E +++ + + R A + EK+ ++ REL++ ++EE
Sbjct: 1099 ALGSQLQKKLKELQARIEELEEELESERTARAKVEKLRSDLSRELEEISERLEEAGGATS 1158
Query: 251 -DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRK----VQQIEEDLEKSEERSGTAQ 415
+ +NK + + K + E+ EA AAL +K V ++ E ++ + +
Sbjct: 1159 VQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLE 1218
Query: 416 QKLLEAQQSADE-NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKL 592
++ E + D+ + M ++++ +A E+ L +Q+ E R AE+ ++++ +
Sbjct: 1219 KEKSEFKLELDDVTSNMEQIIKAKANL-EKMCRTLEDQMNEHRSKAEETQRSVNDLTSQR 1277
Query: 593 AFVEDELEVAEDRVKSGDAKISXL 664
A ++ E ++ +A IS L
Sbjct: 1278 AKLQTENGELSRQLDEKEALISQL 1301
>M57965-1|AAA51837.1| 1935|Homo sapiens beta-myosin heavy chain
protein.
Length = 1935
Score = 54.0 bits (124), Expect = 5e-07
Identities = 44/202 (21%), Positives = 88/202 (43%), Gaps = 12/202 (5%)
Frame = +2
Query: 161 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 340
+ + D + E+ N L KK ++ L K K E++ +LE +K+ + E+
Sbjct: 1422 QNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTEL 1481
Query: 341 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 520
L ++ E LE + + Q+++ + + + + LE +Q E +L
Sbjct: 1482 FKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQ 1541
Query: 521 NQLKEARLLAEDADGK-----------SDEVSRKLAFVEDELEVAE-DRVKSGDAKISXL 664
+ L+EA E +GK E+ RKLA ++E+E A+ + ++ D+ + L
Sbjct: 1542 SALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSL 1601
Query: 665 EXELKVVGNSLKSLEVSEXKAN 730
+ E + +L+ + E N
Sbjct: 1602 DAETRSRNEALRVKKKMEGDLN 1623
Score = 51.6 bits (118), Expect = 3e-06
Identities = 54/227 (23%), Positives = 103/227 (45%), Gaps = 15/227 (6%)
Frame = +2
Query: 95 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEE---DLILN 265
++K+ KLE D+ + + + + +++ E + K + + DL
Sbjct: 1217 LEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQ 1276
Query: 266 KNKLEQANKDLEEKEKQLTATEAEVAALNR----KVQQIEEDLEKSEERSGTAQQKLLEA 433
+ KL+ N +L +QL EA ++ L R QQ+ EDL++ E A+ L A
Sbjct: 1277 RAKLQTENGEL---SRQLDEKEALISQLTRGKLTYTQQL-EDLKRQLEEEVKAKNALAHA 1332
Query: 434 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL-LAE-------DADGKSDEVSRK 589
QSA + C +L + +++ E +L L +A +A+ DA +++E+
Sbjct: 1333 LQSARHD---CDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEA 1389
Query: 590 LAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXKAN 730
+ L+ AE+ V++ +AK S LE + N ++ L V ++N
Sbjct: 1390 KKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSN 1436
Score = 51.6 bits (118), Expect = 3e-06
Identities = 55/228 (24%), Positives = 112/228 (49%), Gaps = 14/228 (6%)
Frame = +2
Query: 86 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAE-KVNEEVRELQKKLAQVEEDLIL 262
++ ++K+++A K+E +A+++A+ + LRA+ + N+ E+++KLA+ +E+
Sbjct: 1526 LEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEE--- 1582
Query: 263 NKNKLEQANKD-LEEKEKQLTATEAEVAALN---RKVQQIEEDLEKSEERSGTAQQKLLE 430
+EQA ++ L + T+ +AE + N R +++E DL + E + A + E
Sbjct: 1583 ----MEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAE 1638
Query: 431 AQQSADENNRMCK----VLENRAQQDEERMDQLT-----NQLKEARLLAEDADGKSDEVS 583
AQ+ + K L++ + +++ + + N L +A L A + E S
Sbjct: 1639 AQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERS 1698
Query: 584 RKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXKA 727
RKLA E EL +RV+ ++ + L + K + L L+ +A
Sbjct: 1699 RKLA--EQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEA 1744
Score = 50.0 bits (114), Expect = 9e-06
Identities = 49/215 (22%), Positives = 104/215 (48%), Gaps = 12/215 (5%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQ----AMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKL 235
++ A + A K+K++ +K + D+ E++ + + + EE+ L + +
Sbjct: 930 EEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEII 989
Query: 236 AQVEEDLILNKNKLEQANKDLE-EKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTA 412
A++ ++ + +QA DL+ E++K T T+A+V K++Q +DLE S E+
Sbjct: 990 AKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKV-----KLEQQVDDLEGSLEQEKKV 1044
Query: 413 QQKLLEAQQSADENNRMCKV----LENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEV 580
+ L A++ + + ++ + LEN QQ +ER+ + +L ED ++
Sbjct: 1045 RMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQL 1104
Query: 581 SRKLAFVEDELEVAEDRVKS---GDAKISXLEXEL 676
+KL ++ +E E+ ++S AK+ L +L
Sbjct: 1105 QKKLKELQARIEELEEELESERTARAKVEKLRSDL 1139
Score = 50.0 bits (114), Expect = 9e-06
Identities = 53/221 (23%), Positives = 98/221 (44%), Gaps = 7/221 (3%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
+++ +A+ +Q+ + + D ++ + + + K N EV + + K E
Sbjct: 1320 EEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKY---E 1376
Query: 248 EDLILNKNKLEQANKDL----EEKEKQLTATEAEVAALNRKVQQIE---EDLEKSEERSG 406
D I +LE+A K L +E E+ + A A+ ++L + +++ EDL ERS
Sbjct: 1377 TDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSN 1436
Query: 407 TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSR 586
A L + Q++ D K+L Q+ EE +L + KEAR L+ + +
Sbjct: 1437 AAAAALDKKQRNFD------KILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEE 1490
Query: 587 KLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLE 709
L + LE + K+ +IS L +L G ++ LE
Sbjct: 1491 SL----EHLETFKRENKNLQEEISDLTEQLGSSGKTIHELE 1527
Score = 48.8 bits (111), Expect = 2e-05
Identities = 48/223 (21%), Positives = 103/223 (46%), Gaps = 19/223 (8%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQA-MKLEKDNAMDKADTCEQ----------QARDANLRAEKVNEEV 214
++K ++ K +Q ++ E+DN D + C+Q + ++ N R E E
Sbjct: 874 EEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMN 933
Query: 215 RELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEK-S 391
EL K ++E++ K ++ L + EK+ ATE +V L ++ ++E + K +
Sbjct: 934 AELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLT 993
Query: 392 EERSG---TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDA- 559
+E+ QQ L + Q D+ N + K + + +Q + ++ Q K+ R+ E A
Sbjct: 994 KEKKALQEAHQQALDDLQAEEDKVNTLTKA-KVKLEQQVDDLEGSLEQEKKVRMDLERAK 1052
Query: 560 ---DGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELK 679
+G + +E++ + ++R+K D +++ L ++
Sbjct: 1053 RKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIE 1095
Score = 46.8 bits (106), Expect = 8e-05
Identities = 33/153 (21%), Positives = 72/153 (47%)
Frame = +2
Query: 164 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 343
QQA D +L+AE+ ++V L K ++E+ + + LEQ K + E+ E ++
Sbjct: 1004 QQALD-DLQAEE--DKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLK 1060
Query: 344 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 523
+ +E D ++ +ER +L ++ + L+ + ++ + R+++L
Sbjct: 1061 LTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEE 1120
Query: 524 QLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 622
+L+ R + ++SR+L + + LE A
Sbjct: 1121 ELESERTARAKVEKLRSDLSRELEEISERLEEA 1153
Score = 42.3 bits (95), Expect = 0.002
Identities = 33/142 (23%), Positives = 66/142 (46%), Gaps = 7/142 (4%)
Frame = +2
Query: 302 EKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLEN 481
E+EK++ A++ + +++E LEKSE R ++K++ Q ++ + ++
Sbjct: 844 EREKEM-------ASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQD 896
Query: 482 RAQQDEERMDQLTN-------QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKS 640
EER DQL ++KE ED + + E++ K +EDE + +
Sbjct: 897 NLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDD 956
Query: 641 GDAKISXLEXELKVVGNSLKSL 706
+ ++ +E E N +K+L
Sbjct: 957 LELTLAKVEKEKHATENKVKNL 978
Score = 35.9 bits (79), Expect = 0.15
Identities = 41/204 (20%), Positives = 94/204 (46%), Gaps = 13/204 (6%)
Frame = +2
Query: 92 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEV-RELQKKLAQVEE------ 250
A+ ++Q E +++ + + R A + EK+ ++ REL++ ++EE
Sbjct: 1099 ALGSQLQKKLKELQARIEELEEELESERTARAKVEKLRSDLSRELEEISERLEEAGGATS 1158
Query: 251 -DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRK----VQQIEEDLEKSEERSGTAQ 415
+ +NK + + K + E+ EA AAL +K V ++ E ++ + +
Sbjct: 1159 VQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLE 1218
Query: 416 QKLLEAQQSADE-NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKL 592
++ E + D+ + M ++++ +A E+ L +Q+ E R AE+ ++++ +
Sbjct: 1219 KEKSEFKLELDDVTSNMEQIIKAKANL-EKMCRTLEDQMNEHRSKAEETQRSVNDLTSQR 1277
Query: 593 AFVEDELEVAEDRVKSGDAKISXL 664
A ++ E ++ +A IS L
Sbjct: 1278 AKLQTENGELSRQLDEKEALISQL 1301
>M25139-1|AAA60385.1| 611|Homo sapiens myosin heavy chain
beta-subunit protein.
Length = 611
Score = 54.0 bits (124), Expect = 5e-07
Identities = 44/202 (21%), Positives = 88/202 (43%), Gaps = 12/202 (5%)
Frame = +2
Query: 161 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 340
+ + D + E+ N L KK ++ L K K E++ +LE +K+ + E+
Sbjct: 98 QNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTEL 157
Query: 341 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 520
L ++ E LE + + Q+++ + + + + LE +Q E +L
Sbjct: 158 FKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQ 217
Query: 521 NQLKEARLLAEDADGK-----------SDEVSRKLAFVEDELEVAE-DRVKSGDAKISXL 664
+ L+EA E +GK E+ RKLA ++E+E A+ + ++ D+ + L
Sbjct: 218 SALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSL 277
Query: 665 EXELKVVGNSLKSLEVSEXKAN 730
+ E + +L+ + E N
Sbjct: 278 DAETRSRNEALRVKKKMEGDLN 299
Score = 50.4 bits (115), Expect = 7e-06
Identities = 45/233 (19%), Positives = 109/233 (46%), Gaps = 19/233 (8%)
Frame = +2
Query: 86 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAE-KVNEEVRELQKKLAQVEEDL-I 259
++ ++K+++A K+E +A+++A+ + LRA+ + N+ E+++KLA+ +E++
Sbjct: 202 LEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQ 261
Query: 260 LNKNKLE-----QANKDLEEK------------EKQLTATEAEVAALNRKVQQIEEDLEK 388
+N L Q + D E + E L E +++ NR + ++ ++
Sbjct: 262 AKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKS 321
Query: 389 SEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGK 568
+ Q +L +A ++ D+ ++E R + +++L +++ + AD +
Sbjct: 322 LQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLADRE 381
Query: 569 SDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXKA 727
E S ++ + + ++ K DA +S L+ E++ ++ E KA
Sbjct: 382 LIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKA 434
Score = 48.8 bits (111), Expect = 2e-05
Identities = 53/214 (24%), Positives = 95/214 (44%), Gaps = 7/214 (3%)
Frame = +2
Query: 89 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 268
+A+ +Q+ + + D ++ + + + K N EV + + K E D I
Sbjct: 3 NALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKY---ETDAIQRT 59
Query: 269 NKLEQANKDL----EEKEKQLTATEAEVAALNRKVQQIE---EDLEKSEERSGTAQQKLL 427
+LE+A K L +E E+ + A A+ ++L + +++ EDL ERS A L
Sbjct: 60 EELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALD 119
Query: 428 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 607
+ Q++ D K+L Q+ EE +L + KEAR L+ + + L +
Sbjct: 120 KKQRNFD------KILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESL----E 169
Query: 608 ELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLE 709
LE + K+ +IS L +L G ++ LE
Sbjct: 170 HLETFKRENKNLQEEISDLTEQLGSSGKTIHELE 203
>M17712-1|AAA36343.1| 543|Homo sapiens protein ( Human cardiac
myosin heavy chain mRNA, 3' end. ).
Length = 543
Score = 54.0 bits (124), Expect = 5e-07
Identities = 44/202 (21%), Positives = 88/202 (43%), Gaps = 12/202 (5%)
Frame = +2
Query: 161 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 340
+ + D + E+ N L KK ++ L K K E++ +LE +K+ + E+
Sbjct: 30 QNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTEL 89
Query: 341 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 520
L ++ E LE + + Q+++ + + + + LE +Q E +L
Sbjct: 90 FKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQ 149
Query: 521 NQLKEARLLAEDADGK-----------SDEVSRKLAFVEDELEVAE-DRVKSGDAKISXL 664
+ L+EA E +GK E+ RKLA ++E+E A+ + ++ D+ + L
Sbjct: 150 SALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSL 209
Query: 665 EXELKVVGNSLKSLEVSEXKAN 730
+ E + +L+ + E N
Sbjct: 210 DAETRSRNEALRVKKKMEGDLN 231
Score = 50.4 bits (115), Expect = 7e-06
Identities = 45/233 (19%), Positives = 109/233 (46%), Gaps = 19/233 (8%)
Frame = +2
Query: 86 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAE-KVNEEVRELQKKLAQVEEDL-I 259
++ ++K+++A K+E +A+++A+ + LRA+ + N+ E+++KLA+ +E++
Sbjct: 134 LEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQ 193
Query: 260 LNKNKLE-----QANKDLEEK------------EKQLTATEAEVAALNRKVQQIEEDLEK 388
+N L Q + D E + E L E +++ NR + ++ ++
Sbjct: 194 AKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKS 253
Query: 389 SEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGK 568
+ Q +L +A ++ D+ ++E R + +++L +++ + AD +
Sbjct: 254 LQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLADRE 313
Query: 569 SDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXKA 727
E S ++ + + ++ K DA +S L+ E++ ++ E KA
Sbjct: 314 LIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKA 366
Score = 39.9 bits (89), Expect = 0.009
Identities = 38/141 (26%), Positives = 65/141 (46%), Gaps = 3/141 (2%)
Frame = +2
Query: 296 LEEKEKQLTATEAEVAALNRKVQQIE---EDLEKSEERSGTAQQKLLEAQQSADENNRMC 466
L+E E+ + A A+ ++L + +++ EDL ERS A L + Q++ D
Sbjct: 5 LQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFD------ 58
Query: 467 KVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGD 646
K+L Q+ EE +L + KEAR L+ + + L + LE + K+
Sbjct: 59 KILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESL----EHLETFKRENKNLQ 114
Query: 647 AKISXLEXELKVVGNSLKSLE 709
+IS L +L G ++ LE
Sbjct: 115 EEISDLTEQLGSSGKTIHELE 135
>EF560725-1|ABQ59035.1| 1934|Homo sapiens MYH7 protein protein.
Length = 1934
Score = 54.0 bits (124), Expect = 5e-07
Identities = 44/202 (21%), Positives = 88/202 (43%), Gaps = 12/202 (5%)
Frame = +2
Query: 161 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 340
+ + D + E+ N L KK ++ L K K E++ +LE +K+ + E+
Sbjct: 1421 QNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTEL 1480
Query: 341 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 520
L ++ E LE + + Q+++ + + + + LE +Q E +L
Sbjct: 1481 FKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQ 1540
Query: 521 NQLKEARLLAEDADGK-----------SDEVSRKLAFVEDELEVAE-DRVKSGDAKISXL 664
+ L+EA E +GK E+ RKLA ++E+E A+ + ++ D+ + L
Sbjct: 1541 SALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSL 1600
Query: 665 EXELKVVGNSLKSLEVSEXKAN 730
+ E + +L+ + E N
Sbjct: 1601 DAETRSRNEALRVKKKMEGDLN 1622
Score = 51.6 bits (118), Expect = 3e-06
Identities = 54/227 (23%), Positives = 103/227 (45%), Gaps = 15/227 (6%)
Frame = +2
Query: 95 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEE---DLILN 265
++K+ KLE D+ + + + + +++ E + K + + DL
Sbjct: 1216 LEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQ 1275
Query: 266 KNKLEQANKDLEEKEKQLTATEAEVAALNR----KVQQIEEDLEKSEERSGTAQQKLLEA 433
+ KL+ N +L +QL EA ++ L R QQ+ EDL++ E A+ L A
Sbjct: 1276 RAKLQTENGEL---SRQLDEKEALISQLTRGKLTYTQQL-EDLKRQLEEEVKAKNALAHA 1331
Query: 434 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL-LAE-------DADGKSDEVSRK 589
QSA + C +L + +++ E +L L +A +A+ DA +++E+
Sbjct: 1332 LQSARHD---CDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEA 1388
Query: 590 LAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXKAN 730
+ L+ AE+ V++ +AK S LE + N ++ L V ++N
Sbjct: 1389 KKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSN 1435
Score = 51.6 bits (118), Expect = 3e-06
Identities = 55/228 (24%), Positives = 112/228 (49%), Gaps = 14/228 (6%)
Frame = +2
Query: 86 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAE-KVNEEVRELQKKLAQVEEDLIL 262
++ ++K+++A K+E +A+++A+ + LRA+ + N+ E+++KLA+ +E+
Sbjct: 1525 LEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEE--- 1581
Query: 263 NKNKLEQANKD-LEEKEKQLTATEAEVAALN---RKVQQIEEDLEKSEERSGTAQQKLLE 430
+EQA ++ L + T+ +AE + N R +++E DL + E + A + E
Sbjct: 1582 ----MEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAE 1637
Query: 431 AQQSADENNRMCK----VLENRAQQDEERMDQLT-----NQLKEARLLAEDADGKSDEVS 583
AQ+ + K L++ + +++ + + N L +A L A + E S
Sbjct: 1638 AQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERS 1697
Query: 584 RKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXKA 727
RKL VE EL +RV+ ++ + L + K + L L+ +A
Sbjct: 1698 RKL--VEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEA 1743
Score = 50.0 bits (114), Expect = 9e-06
Identities = 53/221 (23%), Positives = 98/221 (44%), Gaps = 7/221 (3%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
+++ +A+ +Q+ + + D ++ + + + K N EV + + K E
Sbjct: 1319 EEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKY---E 1375
Query: 248 EDLILNKNKLEQANKDL----EEKEKQLTATEAEVAALNRKVQQIE---EDLEKSEERSG 406
D I +LE+A K L +E E+ + A A+ ++L + +++ EDL ERS
Sbjct: 1376 TDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSN 1435
Query: 407 TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSR 586
A L + Q++ D K+L Q+ EE +L + KEAR L+ + +
Sbjct: 1436 AAAAALDKKQRNFD------KILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEE 1489
Query: 587 KLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLE 709
L + LE + K+ +IS L +L G ++ LE
Sbjct: 1490 SL----EHLETFKRENKNLQEEISDLTEQLGSSGKTIHELE 1526
Score = 49.2 bits (112), Expect = 2e-05
Identities = 48/215 (22%), Positives = 104/215 (48%), Gaps = 12/215 (5%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQ----AMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKL 235
++ A + A K+K++ +K + D+ E++ + + + EE+ L + +
Sbjct: 929 EEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEII 988
Query: 236 AQVEEDLILNKNKLEQANKDLE-EKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTA 412
A++ ++ + +QA DL+ E++K T T+A+V K++Q +DLE S E+
Sbjct: 989 AKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKV-----KLEQQVDDLEGSLEQEKKV 1043
Query: 413 QQKLLEAQQSADENNRMCKV----LENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEV 580
+ L A++ + + ++ + LEN QQ +ER+ + +L ED ++
Sbjct: 1044 RMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQL 1103
Query: 581 SRKLAFVEDELEVAEDRV---KSGDAKISXLEXEL 676
+KL ++ +E E+ + ++ AK+ L +L
Sbjct: 1104 QKKLKELQARIEELEEELEAERTARAKVEKLRSDL 1138
Score = 48.8 bits (111), Expect = 2e-05
Identities = 48/223 (21%), Positives = 103/223 (46%), Gaps = 19/223 (8%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQA-MKLEKDNAMDKADTCEQ----------QARDANLRAEKVNEEV 214
++K ++ K +Q ++ E+DN D + C+Q + ++ N R E E
Sbjct: 873 EEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMN 932
Query: 215 RELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEK-S 391
EL K ++E++ K ++ L + EK+ ATE +V L ++ ++E + K +
Sbjct: 933 AELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLT 992
Query: 392 EERSG---TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDA- 559
+E+ QQ L + Q D+ N + K + + +Q + ++ Q K+ R+ E A
Sbjct: 993 KEKKALQEAHQQALDDLQAEEDKVNTLTKA-KVKLEQQVDDLEGSLEQEKKVRMDLERAK 1051
Query: 560 ---DGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELK 679
+G + +E++ + ++R+K D +++ L ++
Sbjct: 1052 RKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIE 1094
Score = 46.4 bits (105), Expect = 1e-04
Identities = 33/153 (21%), Positives = 72/153 (47%)
Frame = +2
Query: 164 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 343
QQA D +L+AE+ ++V L K ++E+ + + LEQ K + E+ E ++
Sbjct: 1003 QQALD-DLQAEE--DKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLK 1059
Query: 344 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 523
+ +E D ++ +ER +L ++ + L+ + ++ + R+++L
Sbjct: 1060 LTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEE 1119
Query: 524 QLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 622
+L+ R + ++SR+L + + LE A
Sbjct: 1120 ELEAERTARAKVEKLRSDLSRELEEISERLEEA 1152
Score = 42.3 bits (95), Expect = 0.002
Identities = 33/142 (23%), Positives = 66/142 (46%), Gaps = 7/142 (4%)
Frame = +2
Query: 302 EKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLEN 481
E+EK++ A++ + +++E LEKSE R ++K++ Q ++ + ++
Sbjct: 843 EREKEM-------ASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQD 895
Query: 482 RAQQDEERMDQLTN-------QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKS 640
EER DQL ++KE ED + + E++ K +EDE + +
Sbjct: 896 NLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDD 955
Query: 641 GDAKISXLEXELKVVGNSLKSL 706
+ ++ +E E N +K+L
Sbjct: 956 LELTLAKVEKEKHATENKVKNL 977
Score = 35.5 bits (78), Expect = 0.20
Identities = 41/204 (20%), Positives = 94/204 (46%), Gaps = 13/204 (6%)
Frame = +2
Query: 92 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEV-RELQKKLAQVEE------ 250
A+ ++Q E +++ + + R A + EK+ ++ REL++ ++EE
Sbjct: 1098 ALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATS 1157
Query: 251 -DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRK----VQQIEEDLEKSEERSGTAQ 415
+ +NK + + K + E+ EA AAL +K V ++ E ++ + +
Sbjct: 1158 VQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLE 1217
Query: 416 QKLLEAQQSADE-NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKL 592
++ E + D+ + M ++++ +A E+ L +Q+ E R AE+ ++++ +
Sbjct: 1218 KEKSEFKLELDDVTSNMEQIIKAKANL-EKMCRTLEDQMNEHRSKAEETQRSVNDLTSQR 1276
Query: 593 AFVEDELEVAEDRVKSGDAKISXL 664
A ++ E ++ +A IS L
Sbjct: 1277 AKLQTENGELSRQLDEKEALISQL 1300
>EF179180-1|ABN05283.1| 1935|Homo sapiens myosin, heavy chain 7,
cardiac muscle, beta protein.
Length = 1935
Score = 54.0 bits (124), Expect = 5e-07
Identities = 44/202 (21%), Positives = 88/202 (43%), Gaps = 12/202 (5%)
Frame = +2
Query: 161 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 340
+ + D + E+ N L KK ++ L K K E++ +LE +K+ + E+
Sbjct: 1422 QNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTEL 1481
Query: 341 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 520
L ++ E LE + + Q+++ + + + + LE +Q E +L
Sbjct: 1482 FKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQ 1541
Query: 521 NQLKEARLLAEDADGK-----------SDEVSRKLAFVEDELEVAE-DRVKSGDAKISXL 664
+ L+EA E +GK E+ RKLA ++E+E A+ + ++ D+ + L
Sbjct: 1542 SALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSL 1601
Query: 665 EXELKVVGNSLKSLEVSEXKAN 730
+ E + +L+ + E N
Sbjct: 1602 DAETRSRNEALRVKKKMEGDLN 1623
Score = 51.6 bits (118), Expect = 3e-06
Identities = 54/227 (23%), Positives = 103/227 (45%), Gaps = 15/227 (6%)
Frame = +2
Query: 95 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEE---DLILN 265
++K+ KLE D+ + + + + +++ E + K + + DL
Sbjct: 1217 LEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQ 1276
Query: 266 KNKLEQANKDLEEKEKQLTATEAEVAALNR----KVQQIEEDLEKSEERSGTAQQKLLEA 433
+ KL+ N +L +QL EA ++ L R QQ+ EDL++ E A+ L A
Sbjct: 1277 RAKLQTENGEL---SRQLDEKEALISQLTRGKLTYTQQL-EDLKRQLEEEVKAKNALAHA 1332
Query: 434 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL-LAE-------DADGKSDEVSRK 589
QSA + C +L + +++ E +L L +A +A+ DA +++E+
Sbjct: 1333 LQSARHD---CDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEA 1389
Query: 590 LAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXKAN 730
+ L+ AE+ V++ +AK S LE + N ++ L V ++N
Sbjct: 1390 KKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSN 1436
Score = 51.6 bits (118), Expect = 3e-06
Identities = 55/228 (24%), Positives = 112/228 (49%), Gaps = 14/228 (6%)
Frame = +2
Query: 86 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAE-KVNEEVRELQKKLAQVEEDLIL 262
++ ++K+++A K+E +A+++A+ + LRA+ + N+ E+++KLA+ +E+
Sbjct: 1526 LEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEE--- 1582
Query: 263 NKNKLEQANKD-LEEKEKQLTATEAEVAALN---RKVQQIEEDLEKSEERSGTAQQKLLE 430
+EQA ++ L + T+ +AE + N R +++E DL + E + A + E
Sbjct: 1583 ----MEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAE 1638
Query: 431 AQQSADENNRMCK----VLENRAQQDEERMDQLT-----NQLKEARLLAEDADGKSDEVS 583
AQ+ + K L++ + +++ + + N L +A L A + E S
Sbjct: 1639 AQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERS 1698
Query: 584 RKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXKA 727
RKLA E EL +RV+ ++ + L + K + L L+ +A
Sbjct: 1699 RKLA--EQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEA 1744
Score = 50.0 bits (114), Expect = 9e-06
Identities = 53/221 (23%), Positives = 98/221 (44%), Gaps = 7/221 (3%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
+++ +A+ +Q+ + + D ++ + + + K N EV + + K E
Sbjct: 1320 EEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKY---E 1376
Query: 248 EDLILNKNKLEQANKDL----EEKEKQLTATEAEVAALNRKVQQIE---EDLEKSEERSG 406
D I +LE+A K L +E E+ + A A+ ++L + +++ EDL ERS
Sbjct: 1377 TDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSN 1436
Query: 407 TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSR 586
A L + Q++ D K+L Q+ EE +L + KEAR L+ + +
Sbjct: 1437 AAAAALDKKQRNFD------KILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEE 1490
Query: 587 KLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLE 709
L + LE + K+ +IS L +L G ++ LE
Sbjct: 1491 SL----EHLETFKRENKNLQEEISDLTEQLGSSGKTIHELE 1527
Score = 49.2 bits (112), Expect = 2e-05
Identities = 48/215 (22%), Positives = 104/215 (48%), Gaps = 12/215 (5%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQ----AMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKL 235
++ A + A K+K++ +K + D+ E++ + + + EE+ L + +
Sbjct: 930 EEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEII 989
Query: 236 AQVEEDLILNKNKLEQANKDLE-EKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTA 412
A++ ++ + +QA DL+ E++K T T+A+V K++Q +DLE S E+
Sbjct: 990 AKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKV-----KLEQQVDDLEGSLEQEKKV 1044
Query: 413 QQKLLEAQQSADENNRMCKV----LENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEV 580
+ L A++ + + ++ + LEN QQ +ER+ + +L ED ++
Sbjct: 1045 RMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQL 1104
Query: 581 SRKLAFVEDELEVAEDRV---KSGDAKISXLEXEL 676
+KL ++ +E E+ + ++ AK+ L +L
Sbjct: 1105 QKKLKELQARIEELEEELEAERTARAKVEKLRSDL 1139
Score = 48.8 bits (111), Expect = 2e-05
Identities = 48/223 (21%), Positives = 103/223 (46%), Gaps = 19/223 (8%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQA-MKLEKDNAMDKADTCEQ----------QARDANLRAEKVNEEV 214
++K ++ K +Q ++ E+DN D + C+Q + ++ N R E E
Sbjct: 874 EEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMN 933
Query: 215 RELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEK-S 391
EL K ++E++ K ++ L + EK+ ATE +V L ++ ++E + K +
Sbjct: 934 AELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLT 993
Query: 392 EERSG---TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDA- 559
+E+ QQ L + Q D+ N + K + + +Q + ++ Q K+ R+ E A
Sbjct: 994 KEKKALQEAHQQALDDLQAEEDKVNTLTKA-KVKLEQQVDDLEGSLEQEKKVRMDLERAK 1052
Query: 560 ---DGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELK 679
+G + +E++ + ++R+K D +++ L ++
Sbjct: 1053 RKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIE 1095
Score = 46.4 bits (105), Expect = 1e-04
Identities = 33/153 (21%), Positives = 72/153 (47%)
Frame = +2
Query: 164 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 343
QQA D +L+AE+ ++V L K ++E+ + + LEQ K + E+ E ++
Sbjct: 1004 QQALD-DLQAEE--DKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLK 1060
Query: 344 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 523
+ +E D ++ +ER +L ++ + L+ + ++ + R+++L
Sbjct: 1061 LTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEE 1120
Query: 524 QLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 622
+L+ R + ++SR+L + + LE A
Sbjct: 1121 ELEAERTARAKVEKLRSDLSRELEEISERLEEA 1153
Score = 42.3 bits (95), Expect = 0.002
Identities = 33/142 (23%), Positives = 66/142 (46%), Gaps = 7/142 (4%)
Frame = +2
Query: 302 EKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLEN 481
E+EK++ A++ + +++E LEKSE R ++K++ Q ++ + ++
Sbjct: 844 EREKEM-------ASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQD 896
Query: 482 RAQQDEERMDQLTN-------QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKS 640
EER DQL ++KE ED + + E++ K +EDE + +
Sbjct: 897 NLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDD 956
Query: 641 GDAKISXLEXELKVVGNSLKSL 706
+ ++ +E E N +K+L
Sbjct: 957 LELTLAKVEKEKHATENKVKNL 978
Score = 35.5 bits (78), Expect = 0.20
Identities = 41/204 (20%), Positives = 94/204 (46%), Gaps = 13/204 (6%)
Frame = +2
Query: 92 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEV-RELQKKLAQVEE------ 250
A+ ++Q E +++ + + R A + EK+ ++ REL++ ++EE
Sbjct: 1099 ALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATS 1158
Query: 251 -DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRK----VQQIEEDLEKSEERSGTAQ 415
+ +NK + + K + E+ EA AAL +K V ++ E ++ + +
Sbjct: 1159 VQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLE 1218
Query: 416 QKLLEAQQSADE-NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKL 592
++ E + D+ + M ++++ +A E+ L +Q+ E R AE+ ++++ +
Sbjct: 1219 KEKSEFKLELDDVTSNMEQIIKAKANL-EKMCRTLEDQMNEHRSKAEETQRSVNDLTSQR 1277
Query: 593 AFVEDELEVAEDRVKSGDAKISXL 664
A ++ E ++ +A IS L
Sbjct: 1278 AKLQTENGELSRQLDEKEALISQL 1301
>DQ139275-1|ABA43896.1| 1313|Homo sapiens Tax1-binding protein 2
protein.
Length = 1313
Score = 54.0 bits (124), Expect = 5e-07
Identities = 52/216 (24%), Positives = 103/216 (47%), Gaps = 10/216 (4%)
Frame = +2
Query: 101 KKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLE 280
+++++ + E+D + +Q + + R+LQK +A+ EE +L
Sbjct: 819 QELRSAQRERDELRTQTSALNRQLAEMEAERDSATSRARQLQKAVAESEEARRSVDGRLS 878
Query: 281 --QANKDLEEK-----EKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 439
QA L+E+ E++ AT +VA L R +Q E +L S+E+ ++ K E +
Sbjct: 879 GVQAELALQEESVRRSERERRATLDQVATLERSLQATESELRASQEK--ISKMKANETKL 936
Query: 440 SADENNRMCKVL---ENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDE 610
D+ R+ +VL E+R + E + L +L+ +RL G SD ++ A ++D
Sbjct: 937 EGDK-RRLKEVLDASESRTVKLELQRRSLEGELQRSRL------GLSDREAQAQA-LQDR 988
Query: 611 LEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSE 718
++ + +V + K L+ ++ + +L +E SE
Sbjct: 989 VDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESE 1024
Score = 40.7 bits (91), Expect = 0.005
Identities = 43/157 (27%), Positives = 68/157 (43%), Gaps = 11/157 (7%)
Frame = +2
Query: 185 LRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAA----LN 352
L+AEK EV E K +L L+ KL L++ +L+A +A LN
Sbjct: 2 LQAEKA--EVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLN 59
Query: 353 RKVQQIEEDLEKSEERSGTAQQKLLEAQQSAD-------ENNRMCKVLENRAQQDEERMD 511
R V Q+EE+ + R A+Q+ A++ + E + LE + E+ +
Sbjct: 60 RLVAQLEEEKSALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQE 119
Query: 512 QLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 622
L QL R + ++SR+L+ E ELE A
Sbjct: 120 ALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQA 156
Score = 40.7 bits (91), Expect = 0.005
Identities = 35/167 (20%), Positives = 81/167 (48%), Gaps = 4/167 (2%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNA---MDKADTCEQQARDA-NLRAEKVNEEVRELQKKL 235
+Q+A +++++ ++LE++ A ++ + +QA++A + + E +LQ++L
Sbjct: 80 EQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQL 139
Query: 236 AQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQ 415
AQ+ L + +LEQA ++ + + + L E AL ++ + L +E T
Sbjct: 140 AQLSRQLSGREQELEQARREAQRQVEALERAAREKEALAKEHAGLAVQLVAAEREGRTLS 199
Query: 416 QKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAED 556
++ + + ++ + Q E R +QL + +A LLA++
Sbjct: 200 EEATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAE-GQALLLAKE 245
Score = 36.7 bits (81), Expect = 0.086
Identities = 50/194 (25%), Positives = 89/194 (45%), Gaps = 5/194 (2%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
++ A +A+ K+ + ++ A + T ++A L E + + E+Q++LAQ+E
Sbjct: 168 ERAAREKEALAKEHAGLAVQLVAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLE 227
Query: 248 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 427
+ +LE + L ++ LT E+A L QQI EK+ QKL+
Sbjct: 228 A----RREQLEAEGQALLLAKETLTG---ELAGLR---QQIIATQEKASLDKELMAQKLV 277
Query: 428 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEA--RLLAEDADGKSD---EVSRKL 592
+A++ A + R E RA +E+ + +L + + A L AE A +S E L
Sbjct: 278 QAEREAQASLR-----EQRAAHEED-LQRLQREKEAAWRELEAERAQLQSQLQREQEELL 331
Query: 593 AFVEDELEVAEDRV 634
A +E E E + +
Sbjct: 332 ARLEAEKEELSEEI 345
Score = 36.3 bits (80), Expect = 0.11
Identities = 39/176 (22%), Positives = 78/176 (44%), Gaps = 1/176 (0%)
Frame = +2
Query: 155 TCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEA 334
T E+ + D L A+K+ + RE Q A + E ++ L++ ++ E ++L EA
Sbjct: 261 TQEKASLDKELMAQKLVQAEREAQ---ASLREQRAAHEEDLQRLQREKEAAWREL---EA 314
Query: 335 EVAALNRKVQQIEED-LEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMD 511
E A L ++Q+ +E+ L + E +++ QQ DE + + E+
Sbjct: 315 ERAQLQSQLQREQEELLARLEAEKEELSEEIAALQQERDEGLLLA---------ESEKQQ 365
Query: 512 QLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELK 679
L+ + E L+E G ++ +E + A+ R + + ++ L EL+
Sbjct: 366 ALSLKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELR 421
Score = 33.5 bits (73), Expect = 0.80
Identities = 38/195 (19%), Positives = 87/195 (44%)
Frame = +2
Query: 95 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 274
+++ + ++++ A + + + A++ + NEE+R KK E + I
Sbjct: 487 LRESQEGREVQRQEAGELRRSLGEGAKEREA-LRRSNEELRSAVKK---AESERI----S 538
Query: 275 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 454
L+ AN+D KE++L E A+ ++ ++ L++ E + LEA++ E
Sbjct: 539 LKLANED---KEQKLALLEEARTAVGKEAGELRTGLQEVE-------RSRLEARRELQEL 588
Query: 455 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRV 634
R K+L++ + + +L +L +++ ++ + ++L E LEV +
Sbjct: 589 RRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQEL 648
Query: 635 KSGDAKISXLEXELK 679
+ K+ E E +
Sbjct: 649 QVAQRKLQEQEGEFR 663
Score = 33.5 bits (73), Expect = 0.80
Identities = 31/128 (24%), Positives = 61/128 (47%), Gaps = 10/128 (7%)
Frame = +2
Query: 200 VNEEVRELQKKLAQVEED--------LILNKNKLEQANKDLEEKEKQLTATEAEVAALNR 355
+ E + LQ+ LAQ+E + L L K+++ + L++ E++ + + L+
Sbjct: 1146 LQERLGSLQRALAQLEAEKREVERSALRLEKDRV-ALRRTLDKVEREKLRSHEDTVRLSA 1204
Query: 356 KVQQIEEDLEKSEERSGTAQQKL--LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQL 529
+ +++ L +E AQ+++ LEAQ E + LE AQQ + + Q +L
Sbjct: 1205 EKGRLDRTLTGAELELAEAQRQIQQLEAQVVVLEQSHSPAQLEVDAQQQQLELQQEVERL 1264
Query: 530 KEARLLAE 553
+ A+ E
Sbjct: 1265 RSAQAQTE 1272
>CR456526-1|CAG30412.1| 1960|Homo sapiens MYH9 protein.
Length = 1960
Score = 54.0 bits (124), Expect = 5e-07
Identities = 47/189 (24%), Positives = 81/189 (42%)
Frame = +2
Query: 161 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 340
E Q +D ++ N + L KL QVE++ + +LE+ + EKQ+ A+V
Sbjct: 1307 ESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQV 1366
Query: 341 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 520
A + +K++ LE +EE Q+ L Q +E LE + ++ +D L
Sbjct: 1367 ADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLL 1426
Query: 521 NQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLK 700
L R A + + K + + LA E++ A+ + A+ E E K + +
Sbjct: 1427 VDLDHQRQSACNLEKKQKKFDQLLA--EEKTISAKYAEERDRAEAEAREKETKALSLARA 1484
Query: 701 SLEVSEXKA 727
E E KA
Sbjct: 1485 LEEAMEQKA 1493
Score = 51.2 bits (117), Expect = 4e-06
Identities = 52/221 (23%), Positives = 103/221 (46%), Gaps = 23/221 (10%)
Frame = +2
Query: 92 AIKKKMQAMK-LEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 268
A K + +A+K L K A K C ++ D E++ + +E +KKL +E ++I +
Sbjct: 1629 ANKNRDEAIKQLRKLQAQMK--DCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQ 1686
Query: 269 NKL---EQANKDLEEKEKQLTATEA-----------EVAALNRKVQQIEEDLEKSEERSG 406
+L E+A + +++ +L A E L ++ Q+EE+LE+ + +
Sbjct: 1687 EELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTE 1746
Query: 407 TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADG--KS--- 571
+L +A D+ N + + AQ++E QL Q KE ++ ++ +G KS
Sbjct: 1747 LINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYK 1806
Query: 572 ---DEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVV 685
+ K+A +E++L+ ++ ++ E +LK V
Sbjct: 1807 ASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDV 1847
Score = 45.6 bits (103), Expect = 2e-04
Identities = 45/195 (23%), Positives = 92/195 (47%), Gaps = 3/195 (1%)
Frame = +2
Query: 104 KMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDL---ILNKNK 274
KMQ K E++ A E++A N+ +K+ REL+ ++++++EDL ++NK
Sbjct: 1075 KMQLAKKEEELQAALARV-EEEAAQKNMALKKI----RELESQISELQEDLESERASRNK 1129
Query: 275 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 454
E+ +DL E E + TE E + QQ +L E+ +K LE + E
Sbjct: 1130 AEKQKRDLGE-ELEALKTELEDTLDSTAAQQ---ELRSKREQEVNILKKTLEEEAKTHE- 1184
Query: 455 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRV 634
++ E R Q+ + +++L QL++ + + + + + + + +E++V
Sbjct: 1185 ---AQIQEMR-QKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGK 1240
Query: 635 KSGDAKISXLEXELK 679
+ K +E +L+
Sbjct: 1241 GDSEHKRKKVEAQLQ 1255
Score = 43.6 bits (98), Expect = 7e-04
Identities = 49/237 (20%), Positives = 99/237 (41%), Gaps = 17/237 (7%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEK--DNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQ 241
++ A +A +K+ +A+ L + + AM++ E+ + E + ++ K + +
Sbjct: 1463 ERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHE 1522
Query: 242 VEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQ----QIEEDLEKSEERSGT 409
+E+ + ++E+ LEE E +L ATE L +Q Q E DL+ +E+S
Sbjct: 1523 LEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEE 1582
Query: 410 AQQKL------LEAQQSADENNRMC-----KVLENRAQQDEERMDQLTNQLKEARLLAED 556
+++L +EA+ + R K LE + E +D EA
Sbjct: 1583 KKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRK 1642
Query: 557 ADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXKA 727
+ + R+L E + K + K+ +E E+ + L + E ++ +A
Sbjct: 1643 LQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQA 1699
Score = 43.2 bits (97), Expect = 0.001
Identities = 32/145 (22%), Positives = 69/145 (47%), Gaps = 4/145 (2%)
Frame = +2
Query: 206 EEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEK---QLTATEAEVAA-LNRKVQQIE 373
+++ + + +L Q +DL+++ + Q+ +LE+K+K QL A E ++A + + E
Sbjct: 1409 DKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAE 1468
Query: 374 EDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAE 553
+ + E ++ + + L EA + E R+ K + D + + E
Sbjct: 1469 AEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKR 1528
Query: 554 DADGKSDEVSRKLAFVEDELEVAED 628
+ + +E+ +L +EDEL+ ED
Sbjct: 1529 ALEQQVEEMKTQLEELEDELQATED 1553
Score = 43.2 bits (97), Expect = 0.001
Identities = 46/219 (21%), Positives = 100/219 (45%), Gaps = 18/219 (8%)
Frame = +2
Query: 80 ATMDA---IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNE---EVRELQKKLA- 238
AT DA ++ +QAMK + + + D ++ + +R + E E Q+ +A
Sbjct: 1550 ATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAV 1609
Query: 239 ----QVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEK--SEER 400
++E DL + ++ ANK+ +E KQL +A++ R++ E+ ++ +
Sbjct: 1610 AARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAK 1669
Query: 401 SGTAQQKLLEAQQ-SADENNRMCKVLENRAQQD-EERMDQLTNQLKEARLLAED---ADG 565
+ K +EA+ E + + +AQQ+ +E D++ N + L E+ +
Sbjct: 1670 ENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEA 1729
Query: 566 KSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKV 682
+ ++ +L + E+ DR+K + +I + +L +
Sbjct: 1730 RIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNL 1768
Score = 39.5 bits (88), Expect = 0.012
Identities = 54/242 (22%), Positives = 109/242 (45%), Gaps = 26/242 (10%)
Frame = +2
Query: 80 ATMDAIKKKMQAMKLEKDNAMD--KADTCEQQARDANLRAEKVNEEVRELQKKLAQVEED 253
A + ++ ++ A K E + +A E++ R +L+AEK +++Q+ + ++EE
Sbjct: 897 AEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEK-----KKMQQNIQELEEQ 951
Query: 254 LILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEA 433
L ++ ++ + E +L E E L + ++ ++ + E+R L E
Sbjct: 952 LEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEE 1011
Query: 434 QQSA-------DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSR-- 586
++ + +++ M LE R +++E++ +L K R L D+ SD+++
Sbjct: 1012 EEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELE---KTRRKLEGDSTDLSDQIAELQ 1068
Query: 587 --------KLAFVEDELEVAEDRVKSGDA-------KISXLEXELKVVGNSLKSLEVSEX 721
+LA E+EL+ A RV+ A KI LE ++ + L+S S
Sbjct: 1069 AQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRN 1128
Query: 722 KA 727
KA
Sbjct: 1129 KA 1130
Score = 36.7 bits (81), Expect = 0.086
Identities = 44/220 (20%), Positives = 98/220 (44%), Gaps = 14/220 (6%)
Frame = +2
Query: 92 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN 271
++ K++ ++ EK++ ++ + E+ + + ++ +V +++KK+ L +
Sbjct: 1326 SLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEE 1385
Query: 272 KLEQANKDLE----EKEKQLTATEAEVAALNRKVQQIEE---DLEKSEERSGTAQQKLLE 430
+ KDLE E+++ A + R Q++++ DL+ + + ++K +
Sbjct: 1386 VKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKK 1445
Query: 431 AQQ-SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAF--- 598
Q A+E K E R + + E ++ T L AR L E + K++ F
Sbjct: 1446 FDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTE 1505
Query: 599 VEDELEVAEDRVKSG---DAKISXLEXELKVVGNSLKSLE 709
+ED + +D KS + LE +++ + L+ LE
Sbjct: 1506 MEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELE 1545
>BX284668-3|CAH70057.1| 1898|Homo sapiens ciliary rootlet coiled-coil,
rootletin protein.
Length = 1898
Score = 54.0 bits (124), Expect = 5e-07
Identities = 52/216 (24%), Positives = 103/216 (47%), Gaps = 10/216 (4%)
Frame = +2
Query: 101 KKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLE 280
+++++ + E+D + +Q + + R+LQK +A+ EE +L
Sbjct: 1397 QELRSAQRERDELRTQTSALNRQLAEMEAERDSATSRARQLQKAVAESEEARRSVDGRLS 1456
Query: 281 --QANKDLEEK-----EKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 439
QA L+E+ E++ AT +VA L R +Q E +L S+E+ ++ K E +
Sbjct: 1457 GVQAELALQEESVRRSERERRATLDQVATLERSLQATESELRASQEK--ISKMKANETKL 1514
Query: 440 SADENNRMCKVL---ENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDE 610
D+ R+ +VL E+R + E + L +L+ +RL G SD ++ A ++D
Sbjct: 1515 EGDK-RRLKEVLDASESRTVKLELQRRSLEGELQRSRL------GLSDREAQAQA-LQDR 1566
Query: 611 LEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSE 718
++ + +V + K L+ ++ + +L +E SE
Sbjct: 1567 VDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESE 1602
Score = 44.0 bits (99), Expect = 6e-04
Identities = 34/193 (17%), Positives = 79/193 (40%)
Frame = +2
Query: 95 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 274
++ + + EK N +QQA + EK+ EL+++ ++EE+
Sbjct: 475 LRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQD 534
Query: 275 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 454
+ ++LE +QL E + + L +++ ++ E L ++ + Q + E ++ +
Sbjct: 535 GARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKA 594
Query: 455 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRV 634
LE + L + L + L E +++R +A +E+E + R
Sbjct: 595 EAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQ 654
Query: 635 KSGDAKISXLEXE 673
+ + + + E
Sbjct: 655 RQAEQEATVAREE 667
Score = 40.7 bits (91), Expect = 0.005
Identities = 43/157 (27%), Positives = 68/157 (43%), Gaps = 11/157 (7%)
Frame = +2
Query: 185 LRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAA----LN 352
L+AEK EV E K +L L+ KL L++ +L+A +A LN
Sbjct: 580 LQAEKA--EVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLN 637
Query: 353 RKVQQIEEDLEKSEERSGTAQQKLLEAQQSAD-------ENNRMCKVLENRAQQDEERMD 511
R V Q+EE+ + R A+Q+ A++ + E + LE + E+ +
Sbjct: 638 RLVAQLEEEKSALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQE 697
Query: 512 QLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 622
L QL R + ++SR+L+ E ELE A
Sbjct: 698 ALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQA 734
Score = 40.7 bits (91), Expect = 0.005
Identities = 35/167 (20%), Positives = 81/167 (48%), Gaps = 4/167 (2%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNA---MDKADTCEQQARDA-NLRAEKVNEEVRELQKKL 235
+Q+A +++++ ++LE++ A ++ + +QA++A + + E +LQ++L
Sbjct: 658 EQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQL 717
Query: 236 AQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQ 415
AQ+ L + +LEQA ++ + + + L E AL ++ + L +E T
Sbjct: 718 AQLSRQLSGREQELEQARREAQRQVEALERAAREKEALAKEHAGLAVQLVAAEREGRTLS 777
Query: 416 QKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAED 556
++ + + ++ + Q E R +QL + +A LLA++
Sbjct: 778 EEATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAE-GQALLLAKE 823
Score = 36.7 bits (81), Expect = 0.086
Identities = 50/194 (25%), Positives = 89/194 (45%), Gaps = 5/194 (2%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
++ A +A+ K+ + ++ A + T ++A L E + + E+Q++LAQ+E
Sbjct: 746 ERAAREKEALAKEHAGLAVQLVAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLE 805
Query: 248 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 427
+ +LE + L ++ LT E+A L QQI EK+ QKL+
Sbjct: 806 A----RREQLEAEGQALLLAKETLTG---ELAGLR---QQIIATQEKASLDKELMAQKLV 855
Query: 428 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEA--RLLAEDADGKSD---EVSRKL 592
+A++ A + R E RA +E+ + +L + + A L AE A +S E L
Sbjct: 856 QAEREAQASLR-----EQRAAHEED-LQRLQREKEAAWRELEAERAQLQSQLQREQEELL 909
Query: 593 AFVEDELEVAEDRV 634
A +E E E + +
Sbjct: 910 ARLEAEKEELSEEI 923
Score = 36.3 bits (80), Expect = 0.11
Identities = 39/176 (22%), Positives = 78/176 (44%), Gaps = 1/176 (0%)
Frame = +2
Query: 155 TCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEA 334
T E+ + D L A+K+ + RE Q A + E ++ L++ ++ E ++L EA
Sbjct: 839 TQEKASLDKELMAQKLVQAEREAQ---ASLREQRAAHEEDLQRLQREKEAAWREL---EA 892
Query: 335 EVAALNRKVQQIEED-LEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMD 511
E A L ++Q+ +E+ L + E +++ QQ DE + + E+
Sbjct: 893 ERAQLQSQLQREQEELLARLEAEKEELSEEIAALQQERDEGLLLA---------ESEKQQ 943
Query: 512 QLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELK 679
L+ + E L+E G ++ +E + A+ R + + ++ L EL+
Sbjct: 944 ALSLKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELR 999
Score = 33.5 bits (73), Expect = 0.80
Identities = 38/195 (19%), Positives = 87/195 (44%)
Frame = +2
Query: 95 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 274
+++ + ++++ A + + + A++ + NEE+R KK E + I
Sbjct: 1065 LRESQEGREVQRQEAGELRRSLGEGAKEREA-LRRSNEELRSAVKK---AESERI----S 1116
Query: 275 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 454
L+ AN+D KE++L E A+ ++ ++ L++ E + LEA++ E
Sbjct: 1117 LKLANED---KEQKLALLEEARTAVGKEAGELRTGLQEVE-------RSRLEARRELQEL 1166
Query: 455 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRV 634
R K+L++ + + +L +L +++ ++ + ++L E LEV +
Sbjct: 1167 RRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQEL 1226
Query: 635 KSGDAKISXLEXELK 679
+ K+ E E +
Sbjct: 1227 QVAQRKLQEQEGEFR 1241
Score = 33.5 bits (73), Expect = 0.80
Identities = 31/128 (24%), Positives = 61/128 (47%), Gaps = 10/128 (7%)
Frame = +2
Query: 200 VNEEVRELQKKLAQVEED--------LILNKNKLEQANKDLEEKEKQLTATEAEVAALNR 355
+ E + LQ+ LAQ+E + L L K+++ + L++ E++ + + L+
Sbjct: 1724 LQERLGSLQRALAQLEAEKREVERSALRLEKDRV-ALRRTLDKVEREKLRSHEDTVRLSA 1782
Query: 356 KVQQIEEDLEKSEERSGTAQQKL--LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQL 529
+ +++ L +E AQ+++ LEAQ E + LE AQQ + + Q +L
Sbjct: 1783 EKGRLDRTLTGAELELAEAQRQIQQLEAQVVVLEQSHSPAQLEVDAQQQQLELQQEVERL 1842
Query: 530 KEARLLAE 553
+ A+ E
Sbjct: 1843 RSAQAQTE 1850
Score = 31.1 bits (67), Expect = 4.3
Identities = 27/96 (28%), Positives = 44/96 (45%), Gaps = 3/96 (3%)
Frame = +2
Query: 173 RDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKL--EQANKDLEEKEKQLTATEAEVAA 346
R A RAE E+ LQ +L + D +L + L +Q DL++ + TE +A
Sbjct: 228 RLAESRAEAALEKQALLQAQLEEQLRDKVLREKDLAQQQMQSDLDKADLSARVTELGLAV 287
Query: 347 LNRKVQQIEED-LEKSEERSGTAQQKLLEAQQSADE 451
+ Q +E+D + K A + L +Q+A E
Sbjct: 288 KRLEKQNLEKDQVNKDLTEKLEALESLRLQEQAALE 323
>BX284668-2|CAH70055.1| 2017|Homo sapiens ciliary rootlet coiled-coil,
rootletin protein.
Length = 2017
Score = 54.0 bits (124), Expect = 5e-07
Identities = 52/216 (24%), Positives = 103/216 (47%), Gaps = 10/216 (4%)
Frame = +2
Query: 101 KKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLE 280
+++++ + E+D + +Q + + R+LQK +A+ EE +L
Sbjct: 1516 QELRSAQRERDELRTQTSALNRQLAEMEAERDSATSRARQLQKAVAESEEARRSVDGRLS 1575
Query: 281 --QANKDLEEK-----EKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 439
QA L+E+ E++ AT +VA L R +Q E +L S+E+ ++ K E +
Sbjct: 1576 GVQAELALQEESVRRSERERRATLDQVATLERSLQATESELRASQEK--ISKMKANETKL 1633
Query: 440 SADENNRMCKVL---ENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDE 610
D+ R+ +VL E+R + E + L +L+ +RL G SD ++ A ++D
Sbjct: 1634 EGDK-RRLKEVLDASESRTVKLELQRRSLEGELQRSRL------GLSDREAQAQA-LQDR 1685
Query: 611 LEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSE 718
++ + +V + K L+ ++ + +L +E SE
Sbjct: 1686 VDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESE 1721
Score = 44.0 bits (99), Expect = 6e-04
Identities = 34/193 (17%), Positives = 79/193 (40%)
Frame = +2
Query: 95 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 274
++ + + EK N +QQA + EK+ EL+++ ++EE+
Sbjct: 594 LRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQD 653
Query: 275 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 454
+ ++LE +QL E + + L +++ ++ E L ++ + Q + E ++ +
Sbjct: 654 GARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKA 713
Query: 455 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRV 634
LE + L + L + L E +++R +A +E+E + R
Sbjct: 714 EAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQ 773
Query: 635 KSGDAKISXLEXE 673
+ + + + E
Sbjct: 774 RQAEQEATVAREE 786
Score = 40.7 bits (91), Expect = 0.005
Identities = 43/157 (27%), Positives = 68/157 (43%), Gaps = 11/157 (7%)
Frame = +2
Query: 185 LRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAA----LN 352
L+AEK EV E K +L L+ KL L++ +L+A +A LN
Sbjct: 699 LQAEKA--EVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLN 756
Query: 353 RKVQQIEEDLEKSEERSGTAQQKLLEAQQSAD-------ENNRMCKVLENRAQQDEERMD 511
R V Q+EE+ + R A+Q+ A++ + E + LE + E+ +
Sbjct: 757 RLVAQLEEEKSALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQE 816
Query: 512 QLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 622
L QL R + ++SR+L+ E ELE A
Sbjct: 817 ALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQA 853
Score = 40.7 bits (91), Expect = 0.005
Identities = 35/167 (20%), Positives = 81/167 (48%), Gaps = 4/167 (2%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNA---MDKADTCEQQARDA-NLRAEKVNEEVRELQKKL 235
+Q+A +++++ ++LE++ A ++ + +QA++A + + E +LQ++L
Sbjct: 777 EQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQL 836
Query: 236 AQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQ 415
AQ+ L + +LEQA ++ + + + L E AL ++ + L +E T
Sbjct: 837 AQLSRQLSGREQELEQARREAQRQVEALERAAREKEALAKEHAGLAVQLVAAEREGRTLS 896
Query: 416 QKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAED 556
++ + + ++ + Q E R +QL + +A LLA++
Sbjct: 897 EEATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAE-GQALLLAKE 942
Score = 36.7 bits (81), Expect = 0.086
Identities = 50/194 (25%), Positives = 89/194 (45%), Gaps = 5/194 (2%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
++ A +A+ K+ + ++ A + T ++A L E + + E+Q++LAQ+E
Sbjct: 865 ERAAREKEALAKEHAGLAVQLVAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLE 924
Query: 248 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 427
+ +LE + L ++ LT E+A L QQI EK+ QKL+
Sbjct: 925 A----RREQLEAEGQALLLAKETLTG---ELAGLR---QQIIATQEKASLDKELMAQKLV 974
Query: 428 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEA--RLLAEDADGKSD---EVSRKL 592
+A++ A + R E RA +E+ + +L + + A L AE A +S E L
Sbjct: 975 QAEREAQASLR-----EQRAAHEED-LQRLQREKEAAWRELEAERAQLQSQLQREQEELL 1028
Query: 593 AFVEDELEVAEDRV 634
A +E E E + +
Sbjct: 1029 ARLEAEKEELSEEI 1042
Score = 36.3 bits (80), Expect = 0.11
Identities = 39/176 (22%), Positives = 78/176 (44%), Gaps = 1/176 (0%)
Frame = +2
Query: 155 TCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEA 334
T E+ + D L A+K+ + RE Q A + E ++ L++ ++ E ++L EA
Sbjct: 958 TQEKASLDKELMAQKLVQAEREAQ---ASLREQRAAHEEDLQRLQREKEAAWREL---EA 1011
Query: 335 EVAALNRKVQQIEED-LEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMD 511
E A L ++Q+ +E+ L + E +++ QQ DE + + E+
Sbjct: 1012 ERAQLQSQLQREQEELLARLEAEKEELSEEIAALQQERDEGLLLA---------ESEKQQ 1062
Query: 512 QLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELK 679
L+ + E L+E G ++ +E + A+ R + + ++ L EL+
Sbjct: 1063 ALSLKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELR 1118
Score = 33.5 bits (73), Expect = 0.80
Identities = 38/195 (19%), Positives = 87/195 (44%)
Frame = +2
Query: 95 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 274
+++ + ++++ A + + + A++ + NEE+R KK E + I
Sbjct: 1184 LRESQEGREVQRQEAGELRRSLGEGAKEREA-LRRSNEELRSAVKK---AESERI----S 1235
Query: 275 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 454
L+ AN+D KE++L E A+ ++ ++ L++ E + LEA++ E
Sbjct: 1236 LKLANED---KEQKLALLEEARTAVGKEAGELRTGLQEVE-------RSRLEARRELQEL 1285
Query: 455 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRV 634
R K+L++ + + +L +L +++ ++ + ++L E LEV +
Sbjct: 1286 RRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQEL 1345
Query: 635 KSGDAKISXLEXELK 679
+ K+ E E +
Sbjct: 1346 QVAQRKLQEQEGEFR 1360
Score = 33.5 bits (73), Expect = 0.80
Identities = 31/128 (24%), Positives = 61/128 (47%), Gaps = 10/128 (7%)
Frame = +2
Query: 200 VNEEVRELQKKLAQVEED--------LILNKNKLEQANKDLEEKEKQLTATEAEVAALNR 355
+ E + LQ+ LAQ+E + L L K+++ + L++ E++ + + L+
Sbjct: 1843 LQERLGSLQRALAQLEAEKREVERSALRLEKDRV-ALRRTLDKVEREKLRSHEDTVRLSA 1901
Query: 356 KVQQIEEDLEKSEERSGTAQQKL--LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQL 529
+ +++ L +E AQ+++ LEAQ E + LE AQQ + + Q +L
Sbjct: 1902 EKGRLDRTLTGAELELAEAQRQIQQLEAQVVVLEQSHSPAQLEVDAQQQQLELQQEVERL 1961
Query: 530 KEARLLAE 553
+ A+ E
Sbjct: 1962 RSAQAQTE 1969
Score = 31.1 bits (67), Expect = 4.3
Identities = 27/96 (28%), Positives = 44/96 (45%), Gaps = 3/96 (3%)
Frame = +2
Query: 173 RDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKL--EQANKDLEEKEKQLTATEAEVAA 346
R A RAE E+ LQ +L + D +L + L +Q DL++ + TE +A
Sbjct: 347 RLAESRAEAALEKQALLQAQLEEQLRDKVLREKDLAQQQMQSDLDKADLSARVTELGLAV 406
Query: 347 LNRKVQQIEED-LEKSEERSGTAQQKLLEAQQSADE 451
+ Q +E+D + K A + L +Q+A E
Sbjct: 407 KRLEKQNLEKDQVNKDLTEKLEALESLRLQEQAALE 442
>BC142716-1|AAI42717.1| 601|Homo sapiens EPS15L1 protein protein.
Length = 601
Score = 54.0 bits (124), Expect = 5e-07
Identities = 30/135 (22%), Positives = 64/135 (47%)
Frame = +2
Query: 311 KQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQ 490
K+L E+A L R+ +E+D+ + EE ++ E Q D + LE + Q
Sbjct: 384 KELDDISQEIAQLQREKYSLEQDIREKEEAIRQKTSEVQELQNDLDRETSSLQELEAQKQ 443
Query: 491 QDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEX 670
++R+D++ Q + R + D K + ++ ++ ++ +++ E +KS + ++ +
Sbjct: 444 DAQDRLDEMDQQKAKLRDMLSDVRQKCQDETQMISSLKTQIQSQESDLKSQEDDLNRAKS 503
Query: 671 ELKVVGNSLKSLEVS 715
EL + LE S
Sbjct: 504 ELNRLQQEETQLEQS 518
>BC142662-1|AAI42663.1| 600|Homo sapiens EPS15L1 protein protein.
Length = 600
Score = 54.0 bits (124), Expect = 5e-07
Identities = 30/135 (22%), Positives = 64/135 (47%)
Frame = +2
Query: 311 KQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQ 490
K+L E+A L R+ +E+D+ + EE ++ E Q D + LE + Q
Sbjct: 383 KELDDISQEIAQLQREKYSLEQDIREKEEAIRQKTSEVQELQNDLDRETSSLQELEAQKQ 442
Query: 491 QDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEX 670
++R+D++ Q + R + D K + ++ ++ ++ +++ E +KS + ++ +
Sbjct: 443 DAQDRLDEMDQQKAKLRDMLSDVRQKCQDETQMISSLKTQIQSQESDLKSQEDDLNRAKS 502
Query: 671 ELKVVGNSLKSLEVS 715
EL + LE S
Sbjct: 503 ELNRLQQEETQLEQS 517
>BC131590-1|AAI31591.1| 754|Homo sapiens EPS15L1 protein protein.
Length = 754
Score = 54.0 bits (124), Expect = 5e-07
Identities = 30/135 (22%), Positives = 64/135 (47%)
Frame = +2
Query: 311 KQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQ 490
K+L E+A L R+ +E+D+ + EE ++ E Q D + LE + Q
Sbjct: 384 KELDDISQEIAQLQREKYSLEQDIREKEEAIRQKTSEVQELQNDLDRETSSLQELEAQKQ 443
Query: 491 QDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEX 670
++R+D++ Q + R + D K + ++ ++ ++ +++ E +KS + ++ +
Sbjct: 444 DAQDRLDEMDQQKAKLRDMLSDVRQKCQDETQMISSLKTQIQSQESDLKSQEDDLNRAKS 503
Query: 671 ELKVVGNSLKSLEVS 715
EL + LE S
Sbjct: 504 ELNRLQQEETQLEQS 518
>BC112173-1|AAI12174.1| 1935|Homo sapiens myosin, heavy chain 7,
cardiac muscle, beta protein.
Length = 1935
Score = 54.0 bits (124), Expect = 5e-07
Identities = 44/202 (21%), Positives = 88/202 (43%), Gaps = 12/202 (5%)
Frame = +2
Query: 161 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 340
+ + D + E+ N L KK ++ L K K E++ +LE +K+ + E+
Sbjct: 1422 QNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTEL 1481
Query: 341 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 520
L ++ E LE + + Q+++ + + + + LE +Q E +L
Sbjct: 1482 FKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQ 1541
Query: 521 NQLKEARLLAEDADGK-----------SDEVSRKLAFVEDELEVAE-DRVKSGDAKISXL 664
+ L+EA E +GK E+ RKLA ++E+E A+ + ++ D+ + L
Sbjct: 1542 SALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSL 1601
Query: 665 EXELKVVGNSLKSLEVSEXKAN 730
+ E + +L+ + E N
Sbjct: 1602 DAETRSRNEALRVKKKMEGDLN 1623
Score = 51.6 bits (118), Expect = 3e-06
Identities = 54/227 (23%), Positives = 103/227 (45%), Gaps = 15/227 (6%)
Frame = +2
Query: 95 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEE---DLILN 265
++K+ KLE D+ + + + + +++ E + K + + DL
Sbjct: 1217 LEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQ 1276
Query: 266 KNKLEQANKDLEEKEKQLTATEAEVAALNR----KVQQIEEDLEKSEERSGTAQQKLLEA 433
+ KL+ N +L +QL EA ++ L R QQ+ EDL++ E A+ L A
Sbjct: 1277 RAKLQTENGEL---SRQLDEKEALISQLTRGKLTYTQQL-EDLKRQLEEEVKAKNALAHA 1332
Query: 434 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL-LAE-------DADGKSDEVSRK 589
QSA + C +L + +++ E +L L +A +A+ DA +++E+
Sbjct: 1333 LQSARHD---CDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEA 1389
Query: 590 LAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXKAN 730
+ L+ AE+ V++ +AK S LE + N ++ L V ++N
Sbjct: 1390 KKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSN 1436
Score = 51.6 bits (118), Expect = 3e-06
Identities = 55/228 (24%), Positives = 112/228 (49%), Gaps = 14/228 (6%)
Frame = +2
Query: 86 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAE-KVNEEVRELQKKLAQVEEDLIL 262
++ ++K+++A K+E +A+++A+ + LRA+ + N+ E+++KLA+ +E+
Sbjct: 1526 LEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEE--- 1582
Query: 263 NKNKLEQANKD-LEEKEKQLTATEAEVAALN---RKVQQIEEDLEKSEERSGTAQQKLLE 430
+EQA ++ L + T+ +AE + N R +++E DL + E + A + E
Sbjct: 1583 ----MEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAE 1638
Query: 431 AQQSADENNRMCK----VLENRAQQDEERMDQLT-----NQLKEARLLAEDADGKSDEVS 583
AQ+ + K L++ + +++ + + N L +A L A + E S
Sbjct: 1639 AQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERS 1698
Query: 584 RKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXKA 727
RKLA E EL +RV+ ++ + L + K + L L+ +A
Sbjct: 1699 RKLA--EQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEA 1744
Score = 50.0 bits (114), Expect = 9e-06
Identities = 53/221 (23%), Positives = 98/221 (44%), Gaps = 7/221 (3%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
+++ +A+ +Q+ + + D ++ + + + K N EV + + K E
Sbjct: 1320 EEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKY---E 1376
Query: 248 EDLILNKNKLEQANKDL----EEKEKQLTATEAEVAALNRKVQQIE---EDLEKSEERSG 406
D I +LE+A K L +E E+ + A A+ ++L + +++ EDL ERS
Sbjct: 1377 TDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSN 1436
Query: 407 TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSR 586
A L + Q++ D K+L Q+ EE +L + KEAR L+ + +
Sbjct: 1437 AAAAALDKKQRNFD------KILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEE 1490
Query: 587 KLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLE 709
L + LE + K+ +IS L +L G ++ LE
Sbjct: 1491 SL----EHLETFKRENKNLQEEISDLTEQLGSSGKTIHELE 1527
Score = 49.2 bits (112), Expect = 2e-05
Identities = 48/215 (22%), Positives = 104/215 (48%), Gaps = 12/215 (5%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQ----AMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKL 235
++ A + A K+K++ +K + D+ E++ + + + EE+ L + +
Sbjct: 930 EEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEII 989
Query: 236 AQVEEDLILNKNKLEQANKDLE-EKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTA 412
A++ ++ + +QA DL+ E++K T T+A+V K++Q +DLE S E+
Sbjct: 990 AKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKV-----KLEQQVDDLEGSLEQEKKV 1044
Query: 413 QQKLLEAQQSADENNRMCKV----LENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEV 580
+ L A++ + + ++ + LEN QQ +ER+ + +L ED ++
Sbjct: 1045 RMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQL 1104
Query: 581 SRKLAFVEDELEVAEDRV---KSGDAKISXLEXEL 676
+KL ++ +E E+ + ++ AK+ L +L
Sbjct: 1105 QKKLKELQARIEELEEELEAERTARAKVEKLRSDL 1139
Score = 48.8 bits (111), Expect = 2e-05
Identities = 48/223 (21%), Positives = 103/223 (46%), Gaps = 19/223 (8%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQA-MKLEKDNAMDKADTCEQ----------QARDANLRAEKVNEEV 214
++K ++ K +Q ++ E+DN D + C+Q + ++ N R E E
Sbjct: 874 EEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMN 933
Query: 215 RELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEK-S 391
EL K ++E++ K ++ L + EK+ ATE +V L ++ ++E + K +
Sbjct: 934 AELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLT 993
Query: 392 EERSG---TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDA- 559
+E+ QQ L + Q D+ N + K + + +Q + ++ Q K+ R+ E A
Sbjct: 994 KEKKALQEAHQQALDDLQAEEDKVNTLTKA-KVKLEQQVDDLEGSLEQEKKVRMDLERAK 1052
Query: 560 ---DGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELK 679
+G + +E++ + ++R+K D +++ L ++
Sbjct: 1053 RKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIE 1095
Score = 46.4 bits (105), Expect = 1e-04
Identities = 33/153 (21%), Positives = 72/153 (47%)
Frame = +2
Query: 164 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 343
QQA D +L+AE+ ++V L K ++E+ + + LEQ K + E+ E ++
Sbjct: 1004 QQALD-DLQAEE--DKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLK 1060
Query: 344 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 523
+ +E D ++ +ER +L ++ + L+ + ++ + R+++L
Sbjct: 1061 LTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEE 1120
Query: 524 QLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 622
+L+ R + ++SR+L + + LE A
Sbjct: 1121 ELEAERTARAKVEKLRSDLSRELEEISERLEEA 1153
Score = 42.3 bits (95), Expect = 0.002
Identities = 33/142 (23%), Positives = 66/142 (46%), Gaps = 7/142 (4%)
Frame = +2
Query: 302 EKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLEN 481
E+EK++ A++ + +++E LEKSE R ++K++ Q ++ + ++
Sbjct: 844 EREKEM-------ASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQD 896
Query: 482 RAQQDEERMDQLTN-------QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKS 640
EER DQL ++KE ED + + E++ K +EDE + +
Sbjct: 897 NLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDD 956
Query: 641 GDAKISXLEXELKVVGNSLKSL 706
+ ++ +E E N +K+L
Sbjct: 957 LELTLAKVEKEKHATENKVKNL 978
Score = 35.5 bits (78), Expect = 0.20
Identities = 41/204 (20%), Positives = 94/204 (46%), Gaps = 13/204 (6%)
Frame = +2
Query: 92 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEV-RELQKKLAQVEE------ 250
A+ ++Q E +++ + + R A + EK+ ++ REL++ ++EE
Sbjct: 1099 ALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATS 1158
Query: 251 -DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRK----VQQIEEDLEKSEERSGTAQ 415
+ +NK + + K + E+ EA AAL +K V ++ E ++ + +
Sbjct: 1159 VQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLE 1218
Query: 416 QKLLEAQQSADE-NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKL 592
++ E + D+ + M ++++ +A E+ L +Q+ E R AE+ ++++ +
Sbjct: 1219 KEKSEFKLELDDVTSNMEQIIKAKANL-EKMCRTLEDQMNEHRSKAEETQRSVNDLTSQR 1277
Query: 593 AFVEDELEVAEDRVKSGDAKISXL 664
A ++ E ++ +A IS L
Sbjct: 1278 AKLQTENGELSRQLDEKEALISQL 1301
>BC112171-1|AAI12172.1| 1935|Homo sapiens myosin, heavy chain 7,
cardiac muscle, beta protein.
Length = 1935
Score = 54.0 bits (124), Expect = 5e-07
Identities = 44/202 (21%), Positives = 88/202 (43%), Gaps = 12/202 (5%)
Frame = +2
Query: 161 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 340
+ + D + E+ N L KK ++ L K K E++ +LE +K+ + E+
Sbjct: 1422 QNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTEL 1481
Query: 341 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 520
L ++ E LE + + Q+++ + + + + LE +Q E +L
Sbjct: 1482 FKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQ 1541
Query: 521 NQLKEARLLAEDADGK-----------SDEVSRKLAFVEDELEVAE-DRVKSGDAKISXL 664
+ L+EA E +GK E+ RKLA ++E+E A+ + ++ D+ + L
Sbjct: 1542 SALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSL 1601
Query: 665 EXELKVVGNSLKSLEVSEXKAN 730
+ E + +L+ + E N
Sbjct: 1602 DAETRSRNEALRVKKKMEGDLN 1623
Score = 51.6 bits (118), Expect = 3e-06
Identities = 54/227 (23%), Positives = 103/227 (45%), Gaps = 15/227 (6%)
Frame = +2
Query: 95 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEE---DLILN 265
++K+ KLE D+ + + + + +++ E + K + + DL
Sbjct: 1217 LEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQ 1276
Query: 266 KNKLEQANKDLEEKEKQLTATEAEVAALNR----KVQQIEEDLEKSEERSGTAQQKLLEA 433
+ KL+ N +L +QL EA ++ L R QQ+ EDL++ E A+ L A
Sbjct: 1277 RAKLQTENGEL---SRQLDEKEALISQLTRGKLTYTQQL-EDLKRQLEEEVKAKNALAHA 1332
Query: 434 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL-LAE-------DADGKSDEVSRK 589
QSA + C +L + +++ E +L L +A +A+ DA +++E+
Sbjct: 1333 LQSARHD---CDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEA 1389
Query: 590 LAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXKAN 730
+ L+ AE+ V++ +AK S LE + N ++ L V ++N
Sbjct: 1390 KKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSN 1436
Score = 51.6 bits (118), Expect = 3e-06
Identities = 55/228 (24%), Positives = 112/228 (49%), Gaps = 14/228 (6%)
Frame = +2
Query: 86 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAE-KVNEEVRELQKKLAQVEEDLIL 262
++ ++K+++A K+E +A+++A+ + LRA+ + N+ E+++KLA+ +E+
Sbjct: 1526 LEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEE--- 1582
Query: 263 NKNKLEQANKD-LEEKEKQLTATEAEVAALN---RKVQQIEEDLEKSEERSGTAQQKLLE 430
+EQA ++ L + T+ +AE + N R +++E DL + E + A + E
Sbjct: 1583 ----MEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAE 1638
Query: 431 AQQSADENNRMCK----VLENRAQQDEERMDQLT-----NQLKEARLLAEDADGKSDEVS 583
AQ+ + K L++ + +++ + + N L +A L A + E S
Sbjct: 1639 AQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERS 1698
Query: 584 RKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXKA 727
RKLA E EL +RV+ ++ + L + K + L L+ +A
Sbjct: 1699 RKLA--EQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEA 1744
Score = 50.0 bits (114), Expect = 9e-06
Identities = 53/221 (23%), Positives = 98/221 (44%), Gaps = 7/221 (3%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
+++ +A+ +Q+ + + D ++ + + + K N EV + + K E
Sbjct: 1320 EEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKY---E 1376
Query: 248 EDLILNKNKLEQANKDL----EEKEKQLTATEAEVAALNRKVQQIE---EDLEKSEERSG 406
D I +LE+A K L +E E+ + A A+ ++L + +++ EDL ERS
Sbjct: 1377 TDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSN 1436
Query: 407 TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSR 586
A L + Q++ D K+L Q+ EE +L + KEAR L+ + +
Sbjct: 1437 AAAAALDKKQRNFD------KILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEE 1490
Query: 587 KLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLE 709
L + LE + K+ +IS L +L G ++ LE
Sbjct: 1491 SL----EHLETFKRENKNLQEEISDLTEQLGSSGKTIHELE 1527
Score = 49.2 bits (112), Expect = 2e-05
Identities = 48/215 (22%), Positives = 104/215 (48%), Gaps = 12/215 (5%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQ----AMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKL 235
++ A + A K+K++ +K + D+ E++ + + + EE+ L + +
Sbjct: 930 EEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEII 989
Query: 236 AQVEEDLILNKNKLEQANKDLE-EKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTA 412
A++ ++ + +QA DL+ E++K T T+A+V K++Q +DLE S E+
Sbjct: 990 AKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKV-----KLEQQVDDLEGSLEQEKKV 1044
Query: 413 QQKLLEAQQSADENNRMCKV----LENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEV 580
+ L A++ + + ++ + LEN QQ +ER+ + +L ED ++
Sbjct: 1045 RMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQL 1104
Query: 581 SRKLAFVEDELEVAEDRV---KSGDAKISXLEXEL 676
+KL ++ +E E+ + ++ AK+ L +L
Sbjct: 1105 QKKLKELQARIEELEEELEAERTARAKVEKLRSDL 1139
Score = 48.8 bits (111), Expect = 2e-05
Identities = 48/223 (21%), Positives = 103/223 (46%), Gaps = 19/223 (8%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQA-MKLEKDNAMDKADTCEQ----------QARDANLRAEKVNEEV 214
++K ++ K +Q ++ E+DN D + C+Q + ++ N R E E
Sbjct: 874 EEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMN 933
Query: 215 RELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEK-S 391
EL K ++E++ K ++ L + EK+ ATE +V L ++ ++E + K +
Sbjct: 934 AELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLT 993
Query: 392 EERSG---TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDA- 559
+E+ QQ L + Q D+ N + K + + +Q + ++ Q K+ R+ E A
Sbjct: 994 KEKKALQEAHQQALDDLQAEEDKVNTLTKA-KVKLEQQVDDLEGSLEQEKKVRMDLERAK 1052
Query: 560 ---DGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELK 679
+G + +E++ + ++R+K D +++ L ++
Sbjct: 1053 RKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIE 1095
Score = 46.4 bits (105), Expect = 1e-04
Identities = 33/153 (21%), Positives = 72/153 (47%)
Frame = +2
Query: 164 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 343
QQA D +L+AE+ ++V L K ++E+ + + LEQ K + E+ E ++
Sbjct: 1004 QQALD-DLQAEE--DKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLK 1060
Query: 344 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 523
+ +E D ++ +ER +L ++ + L+ + ++ + R+++L
Sbjct: 1061 LTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEE 1120
Query: 524 QLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 622
+L+ R + ++SR+L + + LE A
Sbjct: 1121 ELEAERTARAKVEKLRSDLSRELEEISERLEEA 1153
Score = 42.3 bits (95), Expect = 0.002
Identities = 33/142 (23%), Positives = 66/142 (46%), Gaps = 7/142 (4%)
Frame = +2
Query: 302 EKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLEN 481
E+EK++ A++ + +++E LEKSE R ++K++ Q ++ + ++
Sbjct: 844 EREKEM-------ASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQD 896
Query: 482 RAQQDEERMDQLTN-------QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKS 640
EER DQL ++KE ED + + E++ K +EDE + +
Sbjct: 897 NLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDD 956
Query: 641 GDAKISXLEXELKVVGNSLKSL 706
+ ++ +E E N +K+L
Sbjct: 957 LELTLAKVEKEKHATENKVKNL 978
Score = 35.5 bits (78), Expect = 0.20
Identities = 41/204 (20%), Positives = 94/204 (46%), Gaps = 13/204 (6%)
Frame = +2
Query: 92 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEV-RELQKKLAQVEE------ 250
A+ ++Q E +++ + + R A + EK+ ++ REL++ ++EE
Sbjct: 1099 ALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATS 1158
Query: 251 -DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRK----VQQIEEDLEKSEERSGTAQ 415
+ +NK + + K + E+ EA AAL +K V ++ E ++ + +
Sbjct: 1159 VQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLE 1218
Query: 416 QKLLEAQQSADE-NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKL 592
++ E + D+ + M ++++ +A E+ L +Q+ E R AE+ ++++ +
Sbjct: 1219 KEKSEFKLELDDVTSNMEQIIKAKANL-EKMCRTLEDQMNEHRSKAEETQRSVNDLTSQR 1277
Query: 593 AFVEDELEVAEDRVKSGDAKISXL 664
A ++ E ++ +A IS L
Sbjct: 1278 AKLQTENGELSRQLDEKEALISQL 1301
>BC028423-1|AAH28423.1| 1022|Homo sapiens PMFBP1 protein protein.
Length = 1022
Score = 54.0 bits (124), Expect = 5e-07
Identities = 37/166 (22%), Positives = 79/166 (47%)
Frame = +2
Query: 95 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 274
+K+ + ++ E +N + C Q + + + +++L K++A +E L+ + +
Sbjct: 656 LKENSRKLEEENENLRAELQCCSTQLESSLNKYNTSQQVIQDLNKEIALQKESLMSLQAQ 715
Query: 275 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 454
L++A + E+ Q T T+ AL+RK ++DL ++ E+ + QQS +
Sbjct: 716 LDKALQK-EKHYLQTTITKEAYDALSRKSAACQDDLTQALEKLNHVTSETKSLQQSLTQT 774
Query: 455 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKL 592
LE EERM +L +L++ R ++++ + +KL
Sbjct: 775 QEKKAQLEEEIIAYEERMKKLNTELRKLRGFHQESELEVHAFDKKL 820
Score = 46.4 bits (105), Expect = 1e-04
Identities = 44/210 (20%), Positives = 96/210 (45%), Gaps = 7/210 (3%)
Frame = +2
Query: 119 KLEKDNAMDK--ADTCEQQARDANLRAEKVNEEVRELQKKLAQVEE-DLILNKNKLEQAN 289
KL+K +DK ADT ++ R+ + ++ + +E +VEE L L++ + N
Sbjct: 511 KLQKGLLLDKQKADTIQELQRELQMLQKESSMAEKEQTSNRKRVEELSLELSEALRKLEN 570
Query: 290 KDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCK 469
D E+++ Q T E ++ +N + +I+ + ++ L EA + ++ K
Sbjct: 571 SDKEKRQLQKTVAEQDM-KMNDMLDRIKHQHREQGSIKCKLEEDLQEATKLLEDKREQLK 629
Query: 470 VLENRAQQDEERMDQLTNQLKEA-RLLAEDA---DGKSDEVSRKLAFVEDELEVAEDRVK 637
+ + E ++ L + K+ + L E++ + +++ + +L +LE + ++
Sbjct: 630 KSKEHEKLMEGELEALRQEFKKKDKTLKENSRKLEEENENLRAELQCCSTQLESSLNKYN 689
Query: 638 SGDAKISXLEXELKVVGNSLKSLEVSEXKA 727
+ I L E+ + SL SL+ KA
Sbjct: 690 TSQQVIQDLNKEIALQKESLMSLQAQLDKA 719
Score = 43.6 bits (98), Expect = 7e-04
Identities = 34/151 (22%), Positives = 76/151 (50%), Gaps = 14/151 (9%)
Frame = +2
Query: 95 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 274
IKK ++ ++ +KD+ + + +D + E V+E+ R + K + ++E DL + +
Sbjct: 304 IKKILKHLQEQKDSQCLHVEEYQNLVKDLRVELEAVSEQKRNIMKDMMKLELDLHGLREE 363
Query: 275 ----LEQANKD-------LEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQK 421
+E+ +KD L+E + + T T+ ++ +Q+ +E L++ E++ Q
Sbjct: 364 TSAHIERKDKDITILQCRLQELQLEFTETQKLTLKKDKFLQEKDEMLQELEKKLTQVQNS 423
Query: 422 LLEAQQSADENNRMCKVLE---NRAQQDEER 505
LL+ ++ ++ M LE A+QD+ +
Sbjct: 424 LLKKEKELEKQQCMATELEMTVKEAKQDKSK 454
Score = 40.3 bits (90), Expect = 0.007
Identities = 35/188 (18%), Positives = 87/188 (46%), Gaps = 5/188 (2%)
Frame = +2
Query: 95 IKKKMQAMKLEKDNAMDKADTCEQQAR----DANLRAEKVNEEVRELQKKLAQVEEDLIL 262
++ +++A+ +K N M E + + E+ ++++ LQ +L +++ +
Sbjct: 332 LRVELEAVSEQKRNIMKDMMKLELDLHGLREETSAHIERKDKDITILQCRLQELQLEFTE 391
Query: 263 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 442
+ + +K L+EK++ L E ++ + + + E++LEK + + + + EA+Q
Sbjct: 392 TQKLTLKKDKFLQEKDEMLQELEKKLTQVQNSLLKKEKELEKQQCMATELEMTVKEAKQD 451
Query: 443 ADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAE-DADGKSDEVSRKLAFVEDELEV 619
+ CK L+ Q+ + +++ Q RL E A ++ + + A LE
Sbjct: 452 KSKEAE-CKALQAEVQKLKNSLEEAKQQ---ERLAGEAPAAQQAAQCKEEAALAGCHLED 507
Query: 620 AEDRVKSG 643
+ +++ G
Sbjct: 508 TQRKLQKG 515
Score = 35.9 bits (79), Expect = 0.15
Identities = 40/217 (18%), Positives = 93/217 (42%), Gaps = 9/217 (4%)
Frame = +2
Query: 71 QKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEE 250
Q ++ + + ++++ +K E++ R +K+N E+R+L+ + E
Sbjct: 752 QALEKLNHVTSETKSLQQSLTQTQEKKAQLEEEIIAYEERMKKLNTELRKLRGFHQESEL 811
Query: 251 DLILNKNKLEQANKDLEEKEKQ-------LTATEAEVAALNRKVQQIEED-LEKSEERSG 406
++ KLE+ + + + +KQ L A E ++ ++ ++E+ LE +E
Sbjct: 812 EVHAFDKKLEEMSCQVLQWQKQHQNDLKMLAAKEEQLREFQEEMAALKENLLEDDKEPCC 871
Query: 407 TAQQKL-LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVS 583
Q + + + N+++ LE A+Q + ++L NQL+E G+ D +
Sbjct: 872 LPQWSVPKDTCRLYRGNDQIMTNLEQWAKQQKVANEKLGNQLREQVKYIAKLSGEKDHLH 931
Query: 584 RKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNS 694
+ ++ E + + ++ K K +G S
Sbjct: 932 SVMVHLQQENKKLKKEIEEKKMKAENTRLCTKALGPS 968
Score = 31.9 bits (69), Expect = 2.4
Identities = 37/154 (24%), Positives = 70/154 (45%), Gaps = 10/154 (6%)
Frame = +2
Query: 206 EEVRELQKKLAQV------EEDLILN-KNKLEQANKDLEEKEKQLTATEAEVA---ALNR 355
+E +E QK+L++V ++DLI +NKL +N + E+EK L +A+ A A +R
Sbjct: 233 QEHQETQKRLSEVWQKVSQQDDLIQELRNKLACSNALVLEREKALIKLQADFASCTATHR 292
Query: 356 KVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKE 535
E+ E ++ Q++ +E + K L + E Q N +K+
Sbjct: 293 YPPSSSEECEDIKKILKHLQEQKDSQCLHVEEYQNLVKDLRVELEAVSE---QKRNIMKD 349
Query: 536 ARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVK 637
L D G +E S + + ++ + + R++
Sbjct: 350 MMKLELDLHGLREETSAHIERKDKDITILQCRLQ 383
>AY518538-1|AAT44534.1| 1179|Homo sapiens rhabdomyosarcoma antigen
MU-RMS-40.7B protein.
Length = 1179
Score = 54.0 bits (124), Expect = 5e-07
Identities = 44/202 (21%), Positives = 88/202 (43%), Gaps = 12/202 (5%)
Frame = +2
Query: 161 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 340
+ + D + E+ N L KK ++ L K K E++ +LE +K+ + E+
Sbjct: 666 QNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTEL 725
Query: 341 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 520
L ++ E LE + + Q+++ + + + + LE +Q E +L
Sbjct: 726 FKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQ 785
Query: 521 NQLKEARLLAEDADGK-----------SDEVSRKLAFVEDELEVAE-DRVKSGDAKISXL 664
+ L+EA E +GK E+ RKLA ++E+E A+ + ++ D+ + L
Sbjct: 786 SALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSL 845
Query: 665 EXELKVVGNSLKSLEVSEXKAN 730
+ E + +L+ + E N
Sbjct: 846 DAETRSRNEALRVKKKMEGDLN 867
Score = 51.6 bits (118), Expect = 3e-06
Identities = 55/228 (24%), Positives = 112/228 (49%), Gaps = 14/228 (6%)
Frame = +2
Query: 86 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAE-KVNEEVRELQKKLAQVEEDLIL 262
++ ++K+++A K+E +A+++A+ + LRA+ + N+ E+++KLA+ +E+
Sbjct: 770 LEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEE--- 826
Query: 263 NKNKLEQANKD-LEEKEKQLTATEAEVAALN---RKVQQIEEDLEKSEERSGTAQQKLLE 430
+EQA ++ L + T+ +AE + N R +++E DL + E + A + E
Sbjct: 827 ----MEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAE 882
Query: 431 AQQSADENNRMCK----VLENRAQQDEERMDQLT-----NQLKEARLLAEDADGKSDEVS 583
AQ+ + K L++ + +++ + + N L +A L A + E S
Sbjct: 883 AQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERS 942
Query: 584 RKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXKA 727
RKLA E EL +RV+ ++ + L + K + L L+ +A
Sbjct: 943 RKLA--EQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEA 988
Score = 51.2 bits (117), Expect = 4e-06
Identities = 54/227 (23%), Positives = 103/227 (45%), Gaps = 15/227 (6%)
Frame = +2
Query: 95 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEE---DLILN 265
++K+ KLE D+ + + + + +++ E + K + + DL
Sbjct: 461 LEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQ 520
Query: 266 KNKLEQANKDLEEKEKQLTATEAEVAALNR----KVQQIEEDLEKSEERSGTAQQKLLEA 433
+ KL+ N +L +QL EA ++ L R QQ+ EDL++ E A+ L A
Sbjct: 521 QAKLQTENGEL---SRQLDEKEALISQLTRGKLTYTQQL-EDLKRQLEEEVKAKNALAHA 576
Query: 434 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL-LAE-------DADGKSDEVSRK 589
QSA + C +L + +++ E +L L +A +A+ DA +++E+
Sbjct: 577 LQSARHD---CDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEA 633
Query: 590 LAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXKAN 730
+ L+ AE+ V++ +AK S LE + N ++ L V ++N
Sbjct: 634 KKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSN 680
Score = 50.0 bits (114), Expect = 9e-06
Identities = 53/221 (23%), Positives = 98/221 (44%), Gaps = 7/221 (3%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
+++ +A+ +Q+ + + D ++ + + + K N EV + + K E
Sbjct: 564 EEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKY---E 620
Query: 248 EDLILNKNKLEQANKDL----EEKEKQLTATEAEVAALNRKVQQIE---EDLEKSEERSG 406
D I +LE+A K L +E E+ + A A+ ++L + +++ EDL ERS
Sbjct: 621 TDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSN 680
Query: 407 TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSR 586
A L + Q++ D K+L Q+ EE +L + KEAR L+ + +
Sbjct: 681 AAAAALDKKQRNFD------KILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEE 734
Query: 587 KLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLE 709
L + LE + K+ +IS L +L G ++ LE
Sbjct: 735 SL----EHLETFKRENKNLQEEISDLTEQLGSSGKTIHELE 771
Score = 49.2 bits (112), Expect = 2e-05
Identities = 48/215 (22%), Positives = 104/215 (48%), Gaps = 12/215 (5%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQ----AMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKL 235
++ A + A K+K++ +K + D+ E++ + + + EE+ L + +
Sbjct: 174 EEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEII 233
Query: 236 AQVEEDLILNKNKLEQANKDLE-EKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTA 412
A++ ++ + +QA DL+ E++K T T+A+V K++Q +DLE S E+
Sbjct: 234 AKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKV-----KLEQQVDDLEGSLEQEKKV 288
Query: 413 QQKLLEAQQSADENNRMCKV----LENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEV 580
+ L A++ + + ++ + LEN QQ +ER+ + +L ED ++
Sbjct: 289 RMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQL 348
Query: 581 SRKLAFVEDELEVAEDRV---KSGDAKISXLEXEL 676
+KL ++ +E E+ + ++ AK+ L +L
Sbjct: 349 QKKLKELQARIEELEEELEAERTARAKVEKLRSDL 383
Score = 48.8 bits (111), Expect = 2e-05
Identities = 48/223 (21%), Positives = 103/223 (46%), Gaps = 19/223 (8%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQA-MKLEKDNAMDKADTCEQ----------QARDANLRAEKVNEEV 214
++K ++ K +Q ++ E+DN D + C+Q + ++ N R E E
Sbjct: 118 EEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMN 177
Query: 215 RELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEK-S 391
EL K ++E++ K ++ L + EK+ ATE +V L ++ ++E + K +
Sbjct: 178 AELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLT 237
Query: 392 EERSG---TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDA- 559
+E+ QQ L + Q D+ N + K + + +Q + ++ Q K+ R+ E A
Sbjct: 238 KEKKALQEAHQQALDDLQAEEDKVNTLTKA-KVKLEQQVDDLEGSLEQEKKVRMDLERAK 296
Query: 560 ---DGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELK 679
+G + +E++ + ++R+K D +++ L ++
Sbjct: 297 RKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIE 339
Score = 46.4 bits (105), Expect = 1e-04
Identities = 33/153 (21%), Positives = 72/153 (47%)
Frame = +2
Query: 164 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 343
QQA D +L+AE+ ++V L K ++E+ + + LEQ K + E+ E ++
Sbjct: 248 QQALD-DLQAEE--DKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLK 304
Query: 344 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 523
+ +E D ++ +ER +L ++ + L+ + ++ + R+++L
Sbjct: 305 LTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEE 364
Query: 524 QLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 622
+L+ R + ++SR+L + + LE A
Sbjct: 365 ELEAERTARAKVEKLRSDLSRELEEISERLEEA 397
Score = 42.3 bits (95), Expect = 0.002
Identities = 33/142 (23%), Positives = 66/142 (46%), Gaps = 7/142 (4%)
Frame = +2
Query: 302 EKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLEN 481
E+EK++ A++ + +++E LEKSE R ++K++ Q ++ + ++
Sbjct: 88 EREKEM-------ASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQD 140
Query: 482 RAQQDEERMDQLTN-------QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKS 640
EER DQL ++KE ED + + E++ K +EDE + +
Sbjct: 141 NLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDD 200
Query: 641 GDAKISXLEXELKVVGNSLKSL 706
+ ++ +E E N +K+L
Sbjct: 201 LELTLAKVEKEKHATENKVKNL 222
Score = 35.5 bits (78), Expect = 0.20
Identities = 41/204 (20%), Positives = 94/204 (46%), Gaps = 13/204 (6%)
Frame = +2
Query: 92 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEV-RELQKKLAQVEE------ 250
A+ ++Q E +++ + + R A + EK+ ++ REL++ ++EE
Sbjct: 343 ALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATS 402
Query: 251 -DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRK----VQQIEEDLEKSEERSGTAQ 415
+ +NK + + K + E+ EA AAL +K V ++ E ++ + +
Sbjct: 403 VQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLE 462
Query: 416 QKLLEAQQSADE-NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKL 592
++ E + D+ + M ++++ +A E+ L +Q+ E R AE+ ++++ +
Sbjct: 463 KEKSEFKLELDDVTSNMEQIIKAKANL-EKMCRTLEDQMNEHRSKAEETQRSVNDLTSQQ 521
Query: 593 AFVEDELEVAEDRVKSGDAKISXL 664
A ++ E ++ +A IS L
Sbjct: 522 AKLQTENGELSRQLDEKEALISQL 545
>AL049569-4|CAI20365.1| 1898|Homo sapiens ciliary rootlet coiled-coil,
rootletin protein.
Length = 1898
Score = 54.0 bits (124), Expect = 5e-07
Identities = 52/216 (24%), Positives = 103/216 (47%), Gaps = 10/216 (4%)
Frame = +2
Query: 101 KKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLE 280
+++++ + E+D + +Q + + R+LQK +A+ EE +L
Sbjct: 1397 QELRSAQRERDELRTQTSALNRQLAEMEAERDSATSRARQLQKAVAESEEARRSVDGRLS 1456
Query: 281 --QANKDLEEK-----EKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 439
QA L+E+ E++ AT +VA L R +Q E +L S+E+ ++ K E +
Sbjct: 1457 GVQAELALQEESVRRSERERRATLDQVATLERSLQATESELRASQEK--ISKMKANETKL 1514
Query: 440 SADENNRMCKVL---ENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDE 610
D+ R+ +VL E+R + E + L +L+ +RL G SD ++ A ++D
Sbjct: 1515 EGDK-RRLKEVLDASESRTVKLELQRRSLEGELQRSRL------GLSDREAQAQA-LQDR 1566
Query: 611 LEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSE 718
++ + +V + K L+ ++ + +L +E SE
Sbjct: 1567 VDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESE 1602
Score = 44.0 bits (99), Expect = 6e-04
Identities = 34/193 (17%), Positives = 79/193 (40%)
Frame = +2
Query: 95 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 274
++ + + EK N +QQA + EK+ EL+++ ++EE+
Sbjct: 475 LRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQD 534
Query: 275 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 454
+ ++LE +QL E + + L +++ ++ E L ++ + Q + E ++ +
Sbjct: 535 GARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKA 594
Query: 455 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRV 634
LE + L + L + L E +++R +A +E+E + R
Sbjct: 595 EAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQ 654
Query: 635 KSGDAKISXLEXE 673
+ + + + E
Sbjct: 655 RQAEQEATVAREE 667
Score = 40.7 bits (91), Expect = 0.005
Identities = 43/157 (27%), Positives = 68/157 (43%), Gaps = 11/157 (7%)
Frame = +2
Query: 185 LRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAA----LN 352
L+AEK EV E K +L L+ KL L++ +L+A +A LN
Sbjct: 580 LQAEKA--EVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLN 637
Query: 353 RKVQQIEEDLEKSEERSGTAQQKLLEAQQSAD-------ENNRMCKVLENRAQQDEERMD 511
R V Q+EE+ + R A+Q+ A++ + E + LE + E+ +
Sbjct: 638 RLVAQLEEEKSALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQE 697
Query: 512 QLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 622
L QL R + ++SR+L+ E ELE A
Sbjct: 698 ALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQA 734
Score = 40.7 bits (91), Expect = 0.005
Identities = 35/167 (20%), Positives = 81/167 (48%), Gaps = 4/167 (2%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNA---MDKADTCEQQARDA-NLRAEKVNEEVRELQKKL 235
+Q+A +++++ ++LE++ A ++ + +QA++A + + E +LQ++L
Sbjct: 658 EQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQL 717
Query: 236 AQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQ 415
AQ+ L + +LEQA ++ + + + L E AL ++ + L +E T
Sbjct: 718 AQLSRQLSGREQELEQARREAQRQVEALERAAREKEALAKEHAGLAVQLVAAEREGRTLS 777
Query: 416 QKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAED 556
++ + + ++ + Q E R +QL + +A LLA++
Sbjct: 778 EEATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAE-GQALLLAKE 823
Score = 36.7 bits (81), Expect = 0.086
Identities = 50/194 (25%), Positives = 89/194 (45%), Gaps = 5/194 (2%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
++ A +A+ K+ + ++ A + T ++A L E + + E+Q++LAQ+E
Sbjct: 746 ERAAREKEALAKEHAGLAVQLVAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLE 805
Query: 248 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 427
+ +LE + L ++ LT E+A L QQI EK+ QKL+
Sbjct: 806 A----RREQLEAEGQALLLAKETLTG---ELAGLR---QQIIATQEKASLDKELMAQKLV 855
Query: 428 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEA--RLLAEDADGKSD---EVSRKL 592
+A++ A + R E RA +E+ + +L + + A L AE A +S E L
Sbjct: 856 QAEREAQASLR-----EQRAAHEED-LQRLQREKEAAWRELEAERAQLQSQLQREQEELL 909
Query: 593 AFVEDELEVAEDRV 634
A +E E E + +
Sbjct: 910 ARLEAEKEELSEEI 923
Score = 36.3 bits (80), Expect = 0.11
Identities = 39/176 (22%), Positives = 78/176 (44%), Gaps = 1/176 (0%)
Frame = +2
Query: 155 TCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEA 334
T E+ + D L A+K+ + RE Q A + E ++ L++ ++ E ++L EA
Sbjct: 839 TQEKASLDKELMAQKLVQAEREAQ---ASLREQRAAHEEDLQRLQREKEAAWREL---EA 892
Query: 335 EVAALNRKVQQIEED-LEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMD 511
E A L ++Q+ +E+ L + E +++ QQ DE + + E+
Sbjct: 893 ERAQLQSQLQREQEELLARLEAEKEELSEEIAALQQERDEGLLLA---------ESEKQQ 943
Query: 512 QLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELK 679
L+ + E L+E G ++ +E + A+ R + + ++ L EL+
Sbjct: 944 ALSLKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELR 999
Score = 33.5 bits (73), Expect = 0.80
Identities = 38/195 (19%), Positives = 87/195 (44%)
Frame = +2
Query: 95 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 274
+++ + ++++ A + + + A++ + NEE+R KK E + I
Sbjct: 1065 LRESQEGREVQRQEAGELRRSLGEGAKEREA-LRRSNEELRSAVKK---AESERI----S 1116
Query: 275 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 454
L+ AN+D KE++L E A+ ++ ++ L++ E + LEA++ E
Sbjct: 1117 LKLANED---KEQKLALLEEARTAVGKEAGELRTGLQEVE-------RSRLEARRELQEL 1166
Query: 455 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRV 634
R K+L++ + + +L +L +++ ++ + ++L E LEV +
Sbjct: 1167 RRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQEL 1226
Query: 635 KSGDAKISXLEXELK 679
+ K+ E E +
Sbjct: 1227 QVAQRKLQEQEGEFR 1241
Score = 33.5 bits (73), Expect = 0.80
Identities = 31/128 (24%), Positives = 61/128 (47%), Gaps = 10/128 (7%)
Frame = +2
Query: 200 VNEEVRELQKKLAQVEED--------LILNKNKLEQANKDLEEKEKQLTATEAEVAALNR 355
+ E + LQ+ LAQ+E + L L K+++ + L++ E++ + + L+
Sbjct: 1724 LQERLGSLQRALAQLEAEKREVERSALRLEKDRV-ALRRTLDKVEREKLRSHEDTVRLSA 1782
Query: 356 KVQQIEEDLEKSEERSGTAQQKL--LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQL 529
+ +++ L +E AQ+++ LEAQ E + LE AQQ + + Q +L
Sbjct: 1783 EKGRLDRTLTGAELELAEAQRQIQQLEAQVVVLEQSHSPAQLEVDAQQQQLELQQEVERL 1842
Query: 530 KEARLLAE 553
+ A+ E
Sbjct: 1843 RSAQAQTE 1850
Score = 31.1 bits (67), Expect = 4.3
Identities = 27/96 (28%), Positives = 44/96 (45%), Gaps = 3/96 (3%)
Frame = +2
Query: 173 RDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKL--EQANKDLEEKEKQLTATEAEVAA 346
R A RAE E+ LQ +L + D +L + L +Q DL++ + TE +A
Sbjct: 228 RLAESRAEAALEKQALLQAQLEEQLRDKVLREKDLAQQQMQSDLDKADLSARVTELGLAV 287
Query: 347 LNRKVQQIEED-LEKSEERSGTAQQKLLEAQQSADE 451
+ Q +E+D + K A + L +Q+A E
Sbjct: 288 KRLEKQNLEKDQVNKDLTEKLEALESLRLQEQAALE 323
>AL049569-3|CAI20363.1| 2017|Homo sapiens ciliary rootlet coiled-coil,
rootletin protein.
Length = 2017
Score = 54.0 bits (124), Expect = 5e-07
Identities = 52/216 (24%), Positives = 103/216 (47%), Gaps = 10/216 (4%)
Frame = +2
Query: 101 KKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLE 280
+++++ + E+D + +Q + + R+LQK +A+ EE +L
Sbjct: 1516 QELRSAQRERDELRTQTSALNRQLAEMEAERDSATSRARQLQKAVAESEEARRSVDGRLS 1575
Query: 281 --QANKDLEEK-----EKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 439
QA L+E+ E++ AT +VA L R +Q E +L S+E+ ++ K E +
Sbjct: 1576 GVQAELALQEESVRRSERERRATLDQVATLERSLQATESELRASQEK--ISKMKANETKL 1633
Query: 440 SADENNRMCKVL---ENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDE 610
D+ R+ +VL E+R + E + L +L+ +RL G SD ++ A ++D
Sbjct: 1634 EGDK-RRLKEVLDASESRTVKLELQRRSLEGELQRSRL------GLSDREAQAQA-LQDR 1685
Query: 611 LEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSE 718
++ + +V + K L+ ++ + +L +E SE
Sbjct: 1686 VDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESE 1721
Score = 44.0 bits (99), Expect = 6e-04
Identities = 34/193 (17%), Positives = 79/193 (40%)
Frame = +2
Query: 95 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 274
++ + + EK N +QQA + EK+ EL+++ ++EE+
Sbjct: 594 LRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQD 653
Query: 275 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 454
+ ++LE +QL E + + L +++ ++ E L ++ + Q + E ++ +
Sbjct: 654 GARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKA 713
Query: 455 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRV 634
LE + L + L + L E +++R +A +E+E + R
Sbjct: 714 EAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQ 773
Query: 635 KSGDAKISXLEXE 673
+ + + + E
Sbjct: 774 RQAEQEATVAREE 786
Score = 40.7 bits (91), Expect = 0.005
Identities = 43/157 (27%), Positives = 68/157 (43%), Gaps = 11/157 (7%)
Frame = +2
Query: 185 LRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAA----LN 352
L+AEK EV E K +L L+ KL L++ +L+A +A LN
Sbjct: 699 LQAEKA--EVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLN 756
Query: 353 RKVQQIEEDLEKSEERSGTAQQKLLEAQQSAD-------ENNRMCKVLENRAQQDEERMD 511
R V Q+EE+ + R A+Q+ A++ + E + LE + E+ +
Sbjct: 757 RLVAQLEEEKSALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQE 816
Query: 512 QLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 622
L QL R + ++SR+L+ E ELE A
Sbjct: 817 ALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQA 853
Score = 40.7 bits (91), Expect = 0.005
Identities = 35/167 (20%), Positives = 81/167 (48%), Gaps = 4/167 (2%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNA---MDKADTCEQQARDA-NLRAEKVNEEVRELQKKL 235
+Q+A +++++ ++LE++ A ++ + +QA++A + + E +LQ++L
Sbjct: 777 EQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQL 836
Query: 236 AQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQ 415
AQ+ L + +LEQA ++ + + + L E AL ++ + L +E T
Sbjct: 837 AQLSRQLSGREQELEQARREAQRQVEALERAAREKEALAKEHAGLAVQLVAAEREGRTLS 896
Query: 416 QKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAED 556
++ + + ++ + Q E R +QL + +A LLA++
Sbjct: 897 EEATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAE-GQALLLAKE 942
Score = 36.7 bits (81), Expect = 0.086
Identities = 50/194 (25%), Positives = 89/194 (45%), Gaps = 5/194 (2%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
++ A +A+ K+ + ++ A + T ++A L E + + E+Q++LAQ+E
Sbjct: 865 ERAAREKEALAKEHAGLAVQLVAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLE 924
Query: 248 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 427
+ +LE + L ++ LT E+A L QQI EK+ QKL+
Sbjct: 925 A----RREQLEAEGQALLLAKETLTG---ELAGLR---QQIIATQEKASLDKELMAQKLV 974
Query: 428 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEA--RLLAEDADGKSD---EVSRKL 592
+A++ A + R E RA +E+ + +L + + A L AE A +S E L
Sbjct: 975 QAEREAQASLR-----EQRAAHEED-LQRLQREKEAAWRELEAERAQLQSQLQREQEELL 1028
Query: 593 AFVEDELEVAEDRV 634
A +E E E + +
Sbjct: 1029 ARLEAEKEELSEEI 1042
Score = 36.3 bits (80), Expect = 0.11
Identities = 39/176 (22%), Positives = 78/176 (44%), Gaps = 1/176 (0%)
Frame = +2
Query: 155 TCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEA 334
T E+ + D L A+K+ + RE Q A + E ++ L++ ++ E ++L EA
Sbjct: 958 TQEKASLDKELMAQKLVQAEREAQ---ASLREQRAAHEEDLQRLQREKEAAWREL---EA 1011
Query: 335 EVAALNRKVQQIEED-LEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMD 511
E A L ++Q+ +E+ L + E +++ QQ DE + + E+
Sbjct: 1012 ERAQLQSQLQREQEELLARLEAEKEELSEEIAALQQERDEGLLLA---------ESEKQQ 1062
Query: 512 QLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELK 679
L+ + E L+E G ++ +E + A+ R + + ++ L EL+
Sbjct: 1063 ALSLKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELR 1118
Score = 33.5 bits (73), Expect = 0.80
Identities = 38/195 (19%), Positives = 87/195 (44%)
Frame = +2
Query: 95 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 274
+++ + ++++ A + + + A++ + NEE+R KK E + I
Sbjct: 1184 LRESQEGREVQRQEAGELRRSLGEGAKEREA-LRRSNEELRSAVKK---AESERI----S 1235
Query: 275 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 454
L+ AN+D KE++L E A+ ++ ++ L++ E + LEA++ E
Sbjct: 1236 LKLANED---KEQKLALLEEARTAVGKEAGELRTGLQEVE-------RSRLEARRELQEL 1285
Query: 455 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRV 634
R K+L++ + + +L +L +++ ++ + ++L E LEV +
Sbjct: 1286 RRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQEL 1345
Query: 635 KSGDAKISXLEXELK 679
+ K+ E E +
Sbjct: 1346 QVAQRKLQEQEGEFR 1360
Score = 33.5 bits (73), Expect = 0.80
Identities = 31/128 (24%), Positives = 61/128 (47%), Gaps = 10/128 (7%)
Frame = +2
Query: 200 VNEEVRELQKKLAQVEED--------LILNKNKLEQANKDLEEKEKQLTATEAEVAALNR 355
+ E + LQ+ LAQ+E + L L K+++ + L++ E++ + + L+
Sbjct: 1843 LQERLGSLQRALAQLEAEKREVERSALRLEKDRV-ALRRTLDKVEREKLRSHEDTVRLSA 1901
Query: 356 KVQQIEEDLEKSEERSGTAQQKL--LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQL 529
+ +++ L +E AQ+++ LEAQ E + LE AQQ + + Q +L
Sbjct: 1902 EKGRLDRTLTGAELELAEAQRQIQQLEAQVVVLEQSHSPAQLEVDAQQQQLELQQEVERL 1961
Query: 530 KEARLLAE 553
+ A+ E
Sbjct: 1962 RSAQAQTE 1969
Score = 31.1 bits (67), Expect = 4.3
Identities = 27/96 (28%), Positives = 44/96 (45%), Gaps = 3/96 (3%)
Frame = +2
Query: 173 RDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKL--EQANKDLEEKEKQLTATEAEVAA 346
R A RAE E+ LQ +L + D +L + L +Q DL++ + TE +A
Sbjct: 347 RLAESRAEAALEKQALLQAQLEEQLRDKVLREKDLAQQQMQSDLDKADLSARVTELGLAV 406
Query: 347 LNRKVQQIEED-LEKSEERSGTAQQKLLEAQQSADE 451
+ Q +E+D + K A + L +Q+A E
Sbjct: 407 KRLEKQNLEKDQVNKDLTEKLEALESLRLQEQAALE 442
>AK093285-1|BAC04121.1| 797|Homo sapiens protein ( Homo sapiens
cDNA FLJ35966 fis, clone TESTI2012628, moderately
similar to Mus musculus STAP mRNA for sperm tail
associated protein. ).
Length = 797
Score = 54.0 bits (124), Expect = 5e-07
Identities = 45/173 (26%), Positives = 81/173 (46%), Gaps = 8/173 (4%)
Frame = +2
Query: 98 KKKMQAMKLE---KDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLA-----QVEED 253
K++ A +LE K+ DK+ E +A A ++ K + E + Q++LA Q +E+
Sbjct: 433 KQQCMATELEMTVKEAKQDKSKEAECKALQAEVQKLKNSLEEAKQQERLAAQQAAQCKEE 492
Query: 254 LILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEA 433
L LE + L++ Q T T+ AL+RK ++DL ++ E+ +
Sbjct: 493 AALAGCHLEDTQRKLQKHYLQTTITKEAYDALSRKSAACQDDLTQALEKLNHVTSETKSL 552
Query: 434 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKL 592
QQS + LE EERM +L +L++ R ++++ + +KL
Sbjct: 553 QQSLTQTQEKKAQLEEEIIAYEERMKKLNTELRKLRGFHQESELEVHAFDKKL 605
Score = 48.8 bits (111), Expect = 2e-05
Identities = 48/178 (26%), Positives = 86/178 (48%), Gaps = 6/178 (3%)
Frame = +2
Query: 194 EKVNEEVRELQKKLAQVEEDLILNKNKLEQAN---KDLE---EKEKQLTATEAEVAALNR 355
++ +E ++EL+KKL QV+ L+ + +LE+ +LE ++ KQ + EAE AL
Sbjct: 404 QEKDEMLQELEKKLTQVQNSLLKKEKELEKQQCMATELEMTVKEAKQDKSKEAECKALQA 463
Query: 356 KVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKE 535
+VQ+++ LE+++ QQ+ L AQQ+A CK A ++ +L++
Sbjct: 464 EVQKLKNSLEEAK------QQERLAAQQAAQ-----CK---EEAALAGCHLEDTQRKLQK 509
Query: 536 ARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLE 709
L D +SRK A +D+L A +++ ++ L+ L LE
Sbjct: 510 HYLQTTITKEAYDALSRKSAACQDDLTQALEKLNHVTSETKSLQQSLTQTQEKKAQLE 567
Score = 44.4 bits (100), Expect = 4e-04
Identities = 46/199 (23%), Positives = 95/199 (47%), Gaps = 28/199 (14%)
Frame = +2
Query: 95 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 274
IKK ++ ++ +KD+ + + +D + E V+E+ R + K + ++E DL + +
Sbjct: 304 IKKILKHLQEQKDSQCLHVEEYQNLVKDLRVELEAVSEQKRNIMKDMMKLELDLHGLREE 363
Query: 275 ----LEQANKD-------LEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQK 421
+E+ +KD L+E + + T T+ ++ +Q+ +E L++ E++ Q
Sbjct: 364 TSAHIERKDKDITILQCRLQELQLEFTETQKLTLKKDKFLQEKDEMLQELEKKLTQVQNS 423
Query: 422 LLEAQQSADENNRMCKVLE---NRAQQDEER----------MDQLTNQLKEA----RLLA 550
LL+ ++ ++ M LE A+QD+ + + +L N L+EA RL A
Sbjct: 424 LLKKEKELEKQQCMATELEMTVKEAKQDKSKEAECKALQAEVQKLKNSLEEAKQQERLAA 483
Query: 551 EDADGKSDEVSRKLAFVED 607
+ A +E + +ED
Sbjct: 484 QQAAQCKEEAALAGCHLED 502
Score = 37.9 bits (84), Expect = 0.037
Identities = 28/189 (14%), Positives = 77/189 (40%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
+ K A A++ ++Q +K + A + QQA A + + Q+KL +
Sbjct: 452 KSKEAECKALQAEVQKLKNSLEEAKQQERLAAQQAAQCKEEAALAGCHLEDTQRKLQKHY 511
Query: 248 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 427
+ K + ++ + LT ++ + + + +++ L +++E+ +++++
Sbjct: 512 LQTTITKEAYDALSRKSAACQDDLTQALEKLNHVTSETKSLQQSLTQTQEKKAQLEEEII 571
Query: 428 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 607
++ + N + L Q+ E + +L+E + + LA E+
Sbjct: 572 AYEERMKKLNTELRKLRGFHQESELEVHAFDKKLEEMSCQVLQWQKQHQNDLKMLAAKEE 631
Query: 608 ELEVAEDRV 634
+L ++ +
Sbjct: 632 QLREFQEEM 640
Score = 35.9 bits (79), Expect = 0.15
Identities = 40/217 (18%), Positives = 93/217 (42%), Gaps = 9/217 (4%)
Frame = +2
Query: 71 QKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEE 250
Q ++ + + ++++ +K E++ R +K+N E+R+L+ + E
Sbjct: 537 QALEKLNHVTSETKSLQQSLTQTQEKKAQLEEEIIAYEERMKKLNTELRKLRGFHQESEL 596
Query: 251 DLILNKNKLEQANKDLEEKEKQ-------LTATEAEVAALNRKVQQIEED-LEKSEERSG 406
++ KLE+ + + + +KQ L A E ++ ++ ++E+ LE +E
Sbjct: 597 EVHAFDKKLEEMSCQVLQWQKQHQNDLKMLAAKEEQLREFQEEMAALKENLLEDDKEPCC 656
Query: 407 TAQQKL-LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVS 583
Q + + + N+++ LE A+Q + ++L NQL+E G+ D +
Sbjct: 657 LPQWSVPKDTCRLYRGNDQIMTNLEQWAKQQKVANEKLGNQLREQVKYIAKLSGEKDHLH 716
Query: 584 RKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNS 694
+ ++ E + + ++ K K +G S
Sbjct: 717 SVMVHLQQENKKLKKEIEEKKMKAENTRLCTKALGPS 753
Score = 31.9 bits (69), Expect = 2.4
Identities = 37/154 (24%), Positives = 70/154 (45%), Gaps = 10/154 (6%)
Frame = +2
Query: 206 EEVRELQKKLAQV------EEDLILN-KNKLEQANKDLEEKEKQLTATEAEVA---ALNR 355
+E +E QK+L++V ++DLI +NKL +N + E+EK L +A+ A A +R
Sbjct: 233 QEHQEAQKRLSEVWQKVSQQDDLIQELRNKLACSNALVLEREKALIKLQADFASCTATHR 292
Query: 356 KVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKE 535
E+ E ++ Q++ +E + K L + E Q N +K+
Sbjct: 293 YPPSSSEECEDIKKILKHLQEQKDSQCLHVEEYQNLVKDLRVELEAVSE---QKRNIMKD 349
Query: 536 ARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVK 637
L D G +E S + + ++ + + R++
Sbjct: 350 MMKLELDLHGLREETSAHIERKDKDITILQCRLQ 383
>AJ238393-1|CAC20413.1| 1935|Homo sapiens beta-myosin heavy chain
protein.
Length = 1935
Score = 54.0 bits (124), Expect = 5e-07
Identities = 44/202 (21%), Positives = 88/202 (43%), Gaps = 12/202 (5%)
Frame = +2
Query: 161 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 340
+ + D + E+ N L KK ++ L K K E++ +LE +K+ + E+
Sbjct: 1422 QNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTEL 1481
Query: 341 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 520
L ++ E LE + + Q+++ + + + + LE +Q E +L
Sbjct: 1482 FKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQ 1541
Query: 521 NQLKEARLLAEDADGK-----------SDEVSRKLAFVEDELEVAE-DRVKSGDAKISXL 664
+ L+EA E +GK E+ RKLA ++E+E A+ + ++ D+ + L
Sbjct: 1542 SALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSL 1601
Query: 665 EXELKVVGNSLKSLEVSEXKAN 730
+ E + +L+ + E N
Sbjct: 1602 DAETRSRNEALRVKKKMEGDLN 1623
Score = 51.6 bits (118), Expect = 3e-06
Identities = 54/227 (23%), Positives = 103/227 (45%), Gaps = 15/227 (6%)
Frame = +2
Query: 95 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEE---DLILN 265
++K+ KLE D+ + + + + +++ E + K + + DL
Sbjct: 1217 LEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQ 1276
Query: 266 KNKLEQANKDLEEKEKQLTATEAEVAALNR----KVQQIEEDLEKSEERSGTAQQKLLEA 433
+ KL+ N +L +QL EA ++ L R QQ+ EDL++ E A+ L A
Sbjct: 1277 RAKLQTENGEL---SRQLDEKEALISQLTRGKLTYTQQL-EDLKRQLEEEVKAKNALAHA 1332
Query: 434 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL-LAE-------DADGKSDEVSRK 589
QSA + C +L + +++ E +L L +A +A+ DA +++E+
Sbjct: 1333 LQSARHD---CDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEA 1389
Query: 590 LAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXKAN 730
+ L+ AE+ V++ +AK S LE + N ++ L V ++N
Sbjct: 1390 KKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSN 1436
Score = 51.6 bits (118), Expect = 3e-06
Identities = 55/228 (24%), Positives = 112/228 (49%), Gaps = 14/228 (6%)
Frame = +2
Query: 86 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAE-KVNEEVRELQKKLAQVEEDLIL 262
++ ++K+++A K+E +A+++A+ + LRA+ + N+ E+++KLA+ +E+
Sbjct: 1526 LEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEE--- 1582
Query: 263 NKNKLEQANKD-LEEKEKQLTATEAEVAALN---RKVQQIEEDLEKSEERSGTAQQKLLE 430
+EQA ++ L + T+ +AE + N R +++E DL + E + A + E
Sbjct: 1583 ----MEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAE 1638
Query: 431 AQQSADENNRMCK----VLENRAQQDEERMDQLT-----NQLKEARLLAEDADGKSDEVS 583
AQ+ + K L++ + +++ + + N L +A L A + E S
Sbjct: 1639 AQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERS 1698
Query: 584 RKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXKA 727
RKLA E EL +RV+ ++ + L + K + L L+ +A
Sbjct: 1699 RKLA--EQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEA 1744
Score = 50.0 bits (114), Expect = 9e-06
Identities = 53/221 (23%), Positives = 98/221 (44%), Gaps = 7/221 (3%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
+++ +A+ +Q+ + + D ++ + + + K N EV + + K E
Sbjct: 1320 EEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKY---E 1376
Query: 248 EDLILNKNKLEQANKDL----EEKEKQLTATEAEVAALNRKVQQIE---EDLEKSEERSG 406
D I +LE+A K L +E E+ + A A+ ++L + +++ EDL ERS
Sbjct: 1377 TDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSN 1436
Query: 407 TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSR 586
A L + Q++ D K+L Q+ EE +L + KEAR L+ + +
Sbjct: 1437 AAAAALDKKQRNFD------KILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEE 1490
Query: 587 KLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLE 709
L + LE + K+ +IS L +L G ++ LE
Sbjct: 1491 SL----EHLETFKRENKNLQEEISDLTEQLGSSGKTIHELE 1527
Score = 49.2 bits (112), Expect = 2e-05
Identities = 48/215 (22%), Positives = 104/215 (48%), Gaps = 12/215 (5%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQ----AMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKL 235
++ A + A K+K++ +K + D+ E++ + + + EE+ L + +
Sbjct: 930 EEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEII 989
Query: 236 AQVEEDLILNKNKLEQANKDLE-EKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTA 412
A++ ++ + +QA DL+ E++K T T+A+V K++Q +DLE S E+
Sbjct: 990 AKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKV-----KLEQQVDDLEGSLEQEKKV 1044
Query: 413 QQKLLEAQQSADENNRMCKV----LENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEV 580
+ L A++ + + ++ + LEN QQ +ER+ + +L ED ++
Sbjct: 1045 RMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQL 1104
Query: 581 SRKLAFVEDELEVAEDRV---KSGDAKISXLEXEL 676
+KL ++ +E E+ + ++ AK+ L +L
Sbjct: 1105 QKKLKELQARIEELEEELEAERTARAKVEKLRSDL 1139
Score = 48.8 bits (111), Expect = 2e-05
Identities = 48/223 (21%), Positives = 103/223 (46%), Gaps = 19/223 (8%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQA-MKLEKDNAMDKADTCEQ----------QARDANLRAEKVNEEV 214
++K ++ K +Q ++ E+DN D + C+Q + ++ N R E E
Sbjct: 874 EEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMN 933
Query: 215 RELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEK-S 391
EL K ++E++ K ++ L + EK+ ATE +V L ++ ++E + K +
Sbjct: 934 AELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLT 993
Query: 392 EERSG---TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDA- 559
+E+ QQ L + Q D+ N + K + + +Q + ++ Q K+ R+ E A
Sbjct: 994 KEKKALQEAHQQALDDLQAEEDKVNTLTKA-KVKLEQQVDDLEGSLEQEKKVRMDLERAK 1052
Query: 560 ---DGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELK 679
+G + +E++ + ++R+K D +++ L ++
Sbjct: 1053 RKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIE 1095
Score = 46.4 bits (105), Expect = 1e-04
Identities = 33/153 (21%), Positives = 72/153 (47%)
Frame = +2
Query: 164 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 343
QQA D +L+AE+ ++V L K ++E+ + + LEQ K + E+ E ++
Sbjct: 1004 QQALD-DLQAEE--DKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLK 1060
Query: 344 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 523
+ +E D ++ +ER +L ++ + L+ + ++ + R+++L
Sbjct: 1061 LTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEE 1120
Query: 524 QLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 622
+L+ R + ++SR+L + + LE A
Sbjct: 1121 ELEAERTARAKVEKLRSDLSRELEEISERLEEA 1153
Score = 42.3 bits (95), Expect = 0.002
Identities = 33/142 (23%), Positives = 66/142 (46%), Gaps = 7/142 (4%)
Frame = +2
Query: 302 EKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLEN 481
E+EK++ A++ + +++E LEKSE R ++K++ Q ++ + ++
Sbjct: 844 EREKEM-------ASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQD 896
Query: 482 RAQQDEERMDQLTN-------QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKS 640
EER DQL ++KE ED + + E++ K +EDE + +
Sbjct: 897 NLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDD 956
Query: 641 GDAKISXLEXELKVVGNSLKSL 706
+ ++ +E E N +K+L
Sbjct: 957 LELTLAKVEKEKHATENKVKNL 978
Score = 35.5 bits (78), Expect = 0.20
Identities = 41/204 (20%), Positives = 94/204 (46%), Gaps = 13/204 (6%)
Frame = +2
Query: 92 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEV-RELQKKLAQVEE------ 250
A+ ++Q E +++ + + R A + EK+ ++ REL++ ++EE
Sbjct: 1099 ALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATS 1158
Query: 251 -DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRK----VQQIEEDLEKSEERSGTAQ 415
+ +NK + + K + E+ EA AAL +K V ++ E ++ + +
Sbjct: 1159 CQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLE 1218
Query: 416 QKLLEAQQSADE-NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKL 592
++ E + D+ + M ++++ +A E+ L +Q+ E R AE+ ++++ +
Sbjct: 1219 KEKSEFKLELDDVTSNMEQIIKAKANL-EKMCRTLEDQMNEHRSKAEETQRSVNDLTSQR 1277
Query: 593 AFVEDELEVAEDRVKSGDAKISXL 664
A ++ E ++ +A IS L
Sbjct: 1278 AKLQTENGELSRQLDEKEALISQL 1301
>AF110265-1|AAF21930.1| 864|Homo sapiens epidermal growth factor
receptor substrate EPS15R protein.
Length = 864
Score = 54.0 bits (124), Expect = 5e-07
Identities = 30/135 (22%), Positives = 64/135 (47%)
Frame = +2
Query: 311 KQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQ 490
K+L E+A L R+ +E+D+ + EE ++ E Q D + LE + Q
Sbjct: 384 KELDDISQEIAQLQREKYSLEQDIREKEEAIRQKTSEVQELQNDLDRETSSLQELEAQKQ 443
Query: 491 QDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEX 670
++R+D++ Q + R + D K + ++ ++ ++ +++ E +KS + ++ +
Sbjct: 444 DAQDRLDEMDQQKAKLRDMLSDVRQKCQDETQMISSLKTQIQSQESDLKSQEDDLNRAKS 503
Query: 671 ELKVVGNSLKSLEVS 715
EL + LE S
Sbjct: 504 ELNRLQQEETQLEQS 518
>AB209708-1|BAD92945.1| 1574|Homo sapiens myosin, heavy polypeptide 7,
cardiac muscle, beta variant protein.
Length = 1574
Score = 54.0 bits (124), Expect = 5e-07
Identities = 44/202 (21%), Positives = 88/202 (43%), Gaps = 12/202 (5%)
Frame = +2
Query: 161 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 340
+ + D + E+ N L KK ++ L K K E++ +LE +K+ + E+
Sbjct: 1061 QNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTEL 1120
Query: 341 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 520
L ++ E LE + + Q+++ + + + + LE +Q E +L
Sbjct: 1121 FKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQ 1180
Query: 521 NQLKEARLLAEDADGK-----------SDEVSRKLAFVEDELEVAE-DRVKSGDAKISXL 664
+ L+EA E +GK E+ RKLA ++E+E A+ + ++ D+ + L
Sbjct: 1181 SALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSL 1240
Query: 665 EXELKVVGNSLKSLEVSEXKAN 730
+ E + +L+ + E N
Sbjct: 1241 DAETRSRNEALRVKKKMEGDLN 1262
Score = 51.6 bits (118), Expect = 3e-06
Identities = 54/227 (23%), Positives = 103/227 (45%), Gaps = 15/227 (6%)
Frame = +2
Query: 95 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEE---DLILN 265
++K+ KLE D+ + + + + +++ E + K + + DL
Sbjct: 856 LEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQ 915
Query: 266 KNKLEQANKDLEEKEKQLTATEAEVAALNR----KVQQIEEDLEKSEERSGTAQQKLLEA 433
+ KL+ N +L +QL EA ++ L R QQ+ EDL++ E A+ L A
Sbjct: 916 RAKLQTENGEL---SRQLDEKEALISQLTRGKLTYTQQL-EDLKRQLEEEVKAKNALAHA 971
Query: 434 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL-LAE-------DADGKSDEVSRK 589
QSA + C +L + +++ E +L L +A +A+ DA +++E+
Sbjct: 972 LQSARHD---CDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEA 1028
Query: 590 LAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXKAN 730
+ L+ AE+ V++ +AK S LE + N ++ L V ++N
Sbjct: 1029 KKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSN 1075
Score = 51.6 bits (118), Expect = 3e-06
Identities = 55/228 (24%), Positives = 112/228 (49%), Gaps = 14/228 (6%)
Frame = +2
Query: 86 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAE-KVNEEVRELQKKLAQVEEDLIL 262
++ ++K+++A K+E +A+++A+ + LRA+ + N+ E+++KLA+ +E+
Sbjct: 1165 LEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEE--- 1221
Query: 263 NKNKLEQANKD-LEEKEKQLTATEAEVAALN---RKVQQIEEDLEKSEERSGTAQQKLLE 430
+EQA ++ L + T+ +AE + N R +++E DL + E + A + E
Sbjct: 1222 ----MEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAE 1277
Query: 431 AQQSADENNRMCK----VLENRAQQDEERMDQLT-----NQLKEARLLAEDADGKSDEVS 583
AQ+ + K L++ + +++ + + N L +A L A + E S
Sbjct: 1278 AQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERS 1337
Query: 584 RKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXKA 727
RKLA E EL +RV+ ++ + L + K + L L+ +A
Sbjct: 1338 RKLA--EQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEA 1383
Score = 50.0 bits (114), Expect = 9e-06
Identities = 53/221 (23%), Positives = 98/221 (44%), Gaps = 7/221 (3%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
+++ +A+ +Q+ + + D ++ + + + K N EV + + K E
Sbjct: 959 EEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKY---E 1015
Query: 248 EDLILNKNKLEQANKDL----EEKEKQLTATEAEVAALNRKVQQIE---EDLEKSEERSG 406
D I +LE+A K L +E E+ + A A+ ++L + +++ EDL ERS
Sbjct: 1016 TDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSN 1075
Query: 407 TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSR 586
A L + Q++ D K+L Q+ EE +L + KEAR L+ + +
Sbjct: 1076 AAAAALDKKQRNFD------KILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEE 1129
Query: 587 KLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLE 709
L + LE + K+ +IS L +L G ++ LE
Sbjct: 1130 SL----EHLETFKRENKNLQEEISDLTEQLGSSGKTIHELE 1166
Score = 49.2 bits (112), Expect = 2e-05
Identities = 48/215 (22%), Positives = 104/215 (48%), Gaps = 12/215 (5%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQ----AMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKL 235
++ A + A K+K++ +K + D+ E++ + + + EE+ L + +
Sbjct: 569 EEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEII 628
Query: 236 AQVEEDLILNKNKLEQANKDLE-EKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTA 412
A++ ++ + +QA DL+ E++K T T+A+V K++Q +DLE S E+
Sbjct: 629 AKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKV-----KLEQQVDDLEGSLEQEKKV 683
Query: 413 QQKLLEAQQSADENNRMCKV----LENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEV 580
+ L A++ + + ++ + LEN QQ +ER+ + +L ED ++
Sbjct: 684 RMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQL 743
Query: 581 SRKLAFVEDELEVAEDRV---KSGDAKISXLEXEL 676
+KL ++ +E E+ + ++ AK+ L +L
Sbjct: 744 QKKLKELQARIEELEEELEAERTARAKVEKLRSDL 778
Score = 48.8 bits (111), Expect = 2e-05
Identities = 48/223 (21%), Positives = 103/223 (46%), Gaps = 19/223 (8%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQA-MKLEKDNAMDKADTCEQ----------QARDANLRAEKVNEEV 214
++K ++ K +Q ++ E+DN D + C+Q + ++ N R E E
Sbjct: 513 EEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMN 572
Query: 215 RELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEK-S 391
EL K ++E++ K ++ L + EK+ ATE +V L ++ ++E + K +
Sbjct: 573 AELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLT 632
Query: 392 EERSG---TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDA- 559
+E+ QQ L + Q D+ N + K + + +Q + ++ Q K+ R+ E A
Sbjct: 633 KEKKALQEAHQQALDDLQAEEDKVNTLTKA-KVKLEQQVDDLEGSLEQEKKVRMDLERAK 691
Query: 560 ---DGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELK 679
+G + +E++ + ++R+K D +++ L ++
Sbjct: 692 RKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIE 734
Score = 46.4 bits (105), Expect = 1e-04
Identities = 33/153 (21%), Positives = 72/153 (47%)
Frame = +2
Query: 164 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 343
QQA D +L+AE+ ++V L K ++E+ + + LEQ K + E+ E ++
Sbjct: 643 QQALD-DLQAEE--DKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLK 699
Query: 344 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 523
+ +E D ++ +ER +L ++ + L+ + ++ + R+++L
Sbjct: 700 LTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEE 759
Query: 524 QLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 622
+L+ R + ++SR+L + + LE A
Sbjct: 760 ELEAERTARAKVEKLRSDLSRELEEISERLEEA 792
Score = 42.3 bits (95), Expect = 0.002
Identities = 33/142 (23%), Positives = 66/142 (46%), Gaps = 7/142 (4%)
Frame = +2
Query: 302 EKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLEN 481
E+EK++ A++ + +++E LEKSE R ++K++ Q ++ + ++
Sbjct: 483 EREKEM-------ASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQD 535
Query: 482 RAQQDEERMDQLTN-------QLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKS 640
EER DQL ++KE ED + + E++ K +EDE + +
Sbjct: 536 NLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDD 595
Query: 641 GDAKISXLEXELKVVGNSLKSL 706
+ ++ +E E N +K+L
Sbjct: 596 LELTLAKVEKEKHATENKVKNL 617
Score = 35.5 bits (78), Expect = 0.20
Identities = 41/204 (20%), Positives = 94/204 (46%), Gaps = 13/204 (6%)
Frame = +2
Query: 92 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEV-RELQKKLAQVEE------ 250
A+ ++Q E +++ + + R A + EK+ ++ REL++ ++EE
Sbjct: 738 ALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATS 797
Query: 251 -DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRK----VQQIEEDLEKSEERSGTAQ 415
+ +NK + + K + E+ EA AAL +K V ++ E ++ + +
Sbjct: 798 VQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLE 857
Query: 416 QKLLEAQQSADE-NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKL 592
++ E + D+ + M ++++ +A E+ L +Q+ E R AE+ ++++ +
Sbjct: 858 KEKSEFKLELDDVTSNMEQIIKAKANL-EKMCRTLEDQMNEHRSKAEETQRSVNDLTSQR 916
Query: 593 AFVEDELEVAEDRVKSGDAKISXL 664
A ++ E ++ +A IS L
Sbjct: 917 AKLQTENGELSRQLDEKEALISQL 940
>AB191263-1|BAD52439.1| 1960|Homo sapiens non-muscle myosin heavy
polypeptide 9 protein.
Length = 1960
Score = 54.0 bits (124), Expect = 5e-07
Identities = 47/189 (24%), Positives = 81/189 (42%)
Frame = +2
Query: 161 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 340
E Q +D ++ N + L KL QVE++ + +LE+ + EKQ+ A+V
Sbjct: 1307 ESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQV 1366
Query: 341 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 520
A + +K++ LE +EE Q+ L Q +E LE + ++ +D L
Sbjct: 1367 ADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLL 1426
Query: 521 NQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLK 700
L R A + + K + + LA E++ A+ + A+ E E K + +
Sbjct: 1427 VDLDHQRQSACNLEKKQKKFDQLLA--EEKTISAKYAEERDRAEAEAREKETKALSLARA 1484
Query: 701 SLEVSEXKA 727
E E KA
Sbjct: 1485 LEEAMEQKA 1493
Score = 51.2 bits (117), Expect = 4e-06
Identities = 52/221 (23%), Positives = 103/221 (46%), Gaps = 23/221 (10%)
Frame = +2
Query: 92 AIKKKMQAMK-LEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 268
A K + +A+K L K A K C ++ D E++ + +E +KKL +E ++I +
Sbjct: 1629 ANKNRDEAIKQLRKLQAQMK--DCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQ 1686
Query: 269 NKL---EQANKDLEEKEKQLTATEA-----------EVAALNRKVQQIEEDLEKSEERSG 406
+L E+A + +++ +L A E L ++ Q+EE+LE+ + +
Sbjct: 1687 EELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTE 1746
Query: 407 TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADG--KS--- 571
+L +A D+ N + + AQ++E QL Q KE ++ ++ +G KS
Sbjct: 1747 LINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYK 1806
Query: 572 ---DEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVV 685
+ K+A +E++L+ ++ ++ E +LK V
Sbjct: 1807 ASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDV 1847
Score = 45.6 bits (103), Expect = 2e-04
Identities = 45/195 (23%), Positives = 92/195 (47%), Gaps = 3/195 (1%)
Frame = +2
Query: 104 KMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDL---ILNKNK 274
KMQ K E++ A E++A N+ +K+ REL+ ++++++EDL ++NK
Sbjct: 1075 KMQLAKKEEELQAALARV-EEEAAQKNMALKKI----RELESQISELQEDLESERASRNK 1129
Query: 275 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 454
E+ +DL E E + TE E + QQ +L E+ +K LE + E
Sbjct: 1130 AEKQKRDLGE-ELEALKTELEDTLDSTAAQQ---ELRSKREQEVNILKKTLEEEAKTHE- 1184
Query: 455 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRV 634
++ E R Q+ + +++L QL++ + + + + + + + +E++V
Sbjct: 1185 ---AQIQEMR-QKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGK 1240
Query: 635 KSGDAKISXLEXELK 679
+ K +E +L+
Sbjct: 1241 GDSEHKRKKVEAQLQ 1255
Score = 43.6 bits (98), Expect = 7e-04
Identities = 49/237 (20%), Positives = 99/237 (41%), Gaps = 17/237 (7%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEK--DNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQ 241
++ A +A +K+ +A+ L + + AM++ E+ + E + ++ K + +
Sbjct: 1463 ERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHE 1522
Query: 242 VEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQ----QIEEDLEKSEERSGT 409
+E+ + ++E+ LEE E +L ATE L +Q Q E DL+ +E+S
Sbjct: 1523 LEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEE 1582
Query: 410 AQQKL------LEAQQSADENNRMC-----KVLENRAQQDEERMDQLTNQLKEARLLAED 556
+++L +EA+ + R K LE + E +D EA
Sbjct: 1583 KKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRK 1642
Query: 557 ADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXKA 727
+ + R+L E + K + K+ +E E+ + L + E ++ +A
Sbjct: 1643 LQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQA 1699
Score = 43.2 bits (97), Expect = 0.001
Identities = 32/145 (22%), Positives = 69/145 (47%), Gaps = 4/145 (2%)
Frame = +2
Query: 206 EEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEK---QLTATEAEVAA-LNRKVQQIE 373
+++ + + +L Q +DL+++ + Q+ +LE+K+K QL A E ++A + + E
Sbjct: 1409 DKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAE 1468
Query: 374 EDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAE 553
+ + E ++ + + L EA + E R+ K + D + + E
Sbjct: 1469 AEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKR 1528
Query: 554 DADGKSDEVSRKLAFVEDELEVAED 628
+ + +E+ +L +EDEL+ ED
Sbjct: 1529 ALEQQVEEMKTQLEELEDELQATED 1553
Score = 43.2 bits (97), Expect = 0.001
Identities = 46/219 (21%), Positives = 100/219 (45%), Gaps = 18/219 (8%)
Frame = +2
Query: 80 ATMDA---IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNE---EVRELQKKLA- 238
AT DA ++ +QAMK + + + D ++ + +R + E E Q+ +A
Sbjct: 1550 ATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAV 1609
Query: 239 ----QVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEK--SEER 400
++E DL + ++ ANK+ +E KQL +A++ R++ E+ ++ +
Sbjct: 1610 AARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAK 1669
Query: 401 SGTAQQKLLEAQQ-SADENNRMCKVLENRAQQD-EERMDQLTNQLKEARLLAED---ADG 565
+ K +EA+ E + + +AQQ+ +E D++ N + L E+ +
Sbjct: 1670 ENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEA 1729
Query: 566 KSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKV 682
+ ++ +L + E+ DR+K + +I + +L +
Sbjct: 1730 RIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNL 1768
Score = 39.5 bits (88), Expect = 0.012
Identities = 54/242 (22%), Positives = 109/242 (45%), Gaps = 26/242 (10%)
Frame = +2
Query: 80 ATMDAIKKKMQAMKLEKDNAMD--KADTCEQQARDANLRAEKVNEEVRELQKKLAQVEED 253
A + ++ ++ A K E + +A E++ R +L+AEK +++Q+ + ++EE
Sbjct: 897 AEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEK-----KKMQQNIQELEEQ 951
Query: 254 LILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEA 433
L ++ ++ + E +L E E L + ++ ++ + E+R L E
Sbjct: 952 LEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEE 1011
Query: 434 QQSA-------DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSR-- 586
++ + +++ M LE R +++E++ +L K R L D+ SD+++
Sbjct: 1012 EEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELE---KTRRKLEGDSTDLSDQIAELQ 1068
Query: 587 --------KLAFVEDELEVAEDRVKSGDA-------KISXLEXELKVVGNSLKSLEVSEX 721
+LA E+EL+ A RV+ A KI LE ++ + L+S S
Sbjct: 1069 AQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRN 1128
Query: 722 KA 727
KA
Sbjct: 1129 KA 1130
Score = 36.7 bits (81), Expect = 0.086
Identities = 44/220 (20%), Positives = 98/220 (44%), Gaps = 14/220 (6%)
Frame = +2
Query: 92 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN 271
++ K++ ++ EK++ ++ + E+ + + ++ +V +++KK+ L +
Sbjct: 1326 SLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEE 1385
Query: 272 KLEQANKDLE----EKEKQLTATEAEVAALNRKVQQIEE---DLEKSEERSGTAQQKLLE 430
+ KDLE E+++ A + R Q++++ DL+ + + ++K +
Sbjct: 1386 VKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKK 1445
Query: 431 AQQ-SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAF--- 598
Q A+E K E R + + E ++ T L AR L E + K++ F
Sbjct: 1446 FDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTE 1505
Query: 599 VEDELEVAEDRVKSG---DAKISXLEXELKVVGNSLKSLE 709
+ED + +D KS + LE +++ + L+ LE
Sbjct: 1506 MEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELE 1545
>AB015346-1|BAA88118.1| 864|Homo sapiens Eps15R protein.
Length = 864
Score = 54.0 bits (124), Expect = 5e-07
Identities = 30/135 (22%), Positives = 64/135 (47%)
Frame = +2
Query: 311 KQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQ 490
K+L E+A L R+ +E+D+ + EE ++ E Q D + LE + Q
Sbjct: 384 KELDDISQEIAQLQREKYSLEQDIREKEEAIRQKTSEVQELQNDLDRETSSLQELEAQKQ 443
Query: 491 QDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEX 670
++R+D++ Q + R + D K + ++ ++ ++ +++ E +KS + ++ +
Sbjct: 444 DAQDRLDEMDQQKAKLRDMLSDVRQKCQDETQMISSLKTQIQSQESDLKSQEDDLNRAKS 503
Query: 671 ELKVVGNSLKSLEVS 715
EL + LE S
Sbjct: 504 ELNRLQQEETQLEQS 518
>AB007914-1|BAA32290.2| 1919|Homo sapiens KIAA0445 protein protein.
Length = 1919
Score = 54.0 bits (124), Expect = 5e-07
Identities = 52/216 (24%), Positives = 103/216 (47%), Gaps = 10/216 (4%)
Frame = +2
Query: 101 KKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLE 280
+++++ + E+D + +Q + + R+LQK +A+ EE +L
Sbjct: 1418 QELRSAQRERDELRTQTSALNRQLAEMEAERDSATSRARQLQKAVAESEEARRSVDGRLS 1477
Query: 281 --QANKDLEEK-----EKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 439
QA L+E+ E++ AT +VA L R +Q E +L S+E+ ++ K E +
Sbjct: 1478 GVQAELALQEESVRRSERERRATLDQVATLERSLQATESELRASQEK--ISKMKANETKL 1535
Query: 440 SADENNRMCKVL---ENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDE 610
D+ R+ +VL E+R + E + L +L+ +RL G SD ++ A ++D
Sbjct: 1536 EGDK-RRLKEVLDASESRTVKLELQRRSLEGELQRSRL------GLSDREAQAQA-LQDR 1587
Query: 611 LEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSE 718
++ + +V + K L+ ++ + +L +E SE
Sbjct: 1588 VDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESE 1623
Score = 44.0 bits (99), Expect = 6e-04
Identities = 34/193 (17%), Positives = 79/193 (40%)
Frame = +2
Query: 95 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 274
++ + + EK N +QQA + EK+ EL+++ ++EE+
Sbjct: 496 LRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQD 555
Query: 275 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 454
+ ++LE +QL E + + L +++ ++ E L ++ + Q + E ++ +
Sbjct: 556 GARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKA 615
Query: 455 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRV 634
LE + L + L + L E +++R +A +E+E + R
Sbjct: 616 EAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQ 675
Query: 635 KSGDAKISXLEXE 673
+ + + + E
Sbjct: 676 RQAEQEATVAREE 688
Score = 40.7 bits (91), Expect = 0.005
Identities = 43/157 (27%), Positives = 68/157 (43%), Gaps = 11/157 (7%)
Frame = +2
Query: 185 LRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAA----LN 352
L+AEK EV E K +L L+ KL L++ +L+A +A LN
Sbjct: 601 LQAEKA--EVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLN 658
Query: 353 RKVQQIEEDLEKSEERSGTAQQKLLEAQQSAD-------ENNRMCKVLENRAQQDEERMD 511
R V Q+EE+ + R A+Q+ A++ + E + LE + E+ +
Sbjct: 659 RLVAQLEEEKSALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQE 718
Query: 512 QLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 622
L QL R + ++SR+L+ E ELE A
Sbjct: 719 ALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQA 755
Score = 40.7 bits (91), Expect = 0.005
Identities = 35/167 (20%), Positives = 81/167 (48%), Gaps = 4/167 (2%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNA---MDKADTCEQQARDA-NLRAEKVNEEVRELQKKL 235
+Q+A +++++ ++LE++ A ++ + +QA++A + + E +LQ++L
Sbjct: 679 EQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQL 738
Query: 236 AQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQ 415
AQ+ L + +LEQA ++ + + + L E AL ++ + L +E T
Sbjct: 739 AQLSRQLSGREQELEQARREAQRQVEALERAAREKEALAKEHAGLAVQLVAAEREGRTLS 798
Query: 416 QKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAED 556
++ + + ++ + Q E R +QL + +A LLA++
Sbjct: 799 EEATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAE-GQALLLAKE 844
Score = 36.7 bits (81), Expect = 0.086
Identities = 50/194 (25%), Positives = 89/194 (45%), Gaps = 5/194 (2%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
++ A +A+ K+ + ++ A + T ++A L E + + E+Q++LAQ+E
Sbjct: 767 ERAAREKEALAKEHAGLAVQLVAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLE 826
Query: 248 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 427
+ +LE + L ++ LT E+A L QQI EK+ QKL+
Sbjct: 827 A----RREQLEAEGQALLLAKETLTG---ELAGLR---QQIIATQEKASLDKELMAQKLV 876
Query: 428 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEA--RLLAEDADGKSD---EVSRKL 592
+A++ A + R E RA +E+ + +L + + A L AE A +S E L
Sbjct: 877 QAEREAQASLR-----EQRAAHEED-LQRLQREKEAAWRELEAERAQLQSQLQREQEELL 930
Query: 593 AFVEDELEVAEDRV 634
A +E E E + +
Sbjct: 931 ARLEAEKEELSEEI 944
Score = 36.3 bits (80), Expect = 0.11
Identities = 39/176 (22%), Positives = 78/176 (44%), Gaps = 1/176 (0%)
Frame = +2
Query: 155 TCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEA 334
T E+ + D L A+K+ + RE Q A + E ++ L++ ++ E ++L EA
Sbjct: 860 TQEKASLDKELMAQKLVQAEREAQ---ASLREQRAAHEEDLQRLQREKEAAWREL---EA 913
Query: 335 EVAALNRKVQQIEED-LEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMD 511
E A L ++Q+ +E+ L + E +++ QQ DE + + E+
Sbjct: 914 ERAQLQSQLQREQEELLARLEAEKEELSEEIAALQQERDEGLLLA---------ESEKQQ 964
Query: 512 QLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELK 679
L+ + E L+E G ++ +E + A+ R + + ++ L EL+
Sbjct: 965 ALSLKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELR 1020
Score = 33.5 bits (73), Expect = 0.80
Identities = 38/195 (19%), Positives = 87/195 (44%)
Frame = +2
Query: 95 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 274
+++ + ++++ A + + + A++ + NEE+R KK E + I
Sbjct: 1086 LRESQEGREVQRQEAGELRRSLGEGAKEREA-LRRSNEELRSAVKK---AESERI----S 1137
Query: 275 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 454
L+ AN+D KE++L E A+ ++ ++ L++ E + LEA++ E
Sbjct: 1138 LKLANED---KEQKLALLEEARTAVGKEAGELRTGLQEVE-------RSRLEARRELQEL 1187
Query: 455 NRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRV 634
R K+L++ + + +L +L +++ ++ + ++L E LEV +
Sbjct: 1188 RRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQEL 1247
Query: 635 KSGDAKISXLEXELK 679
+ K+ E E +
Sbjct: 1248 QVAQRKLQEQEGEFR 1262
Score = 33.5 bits (73), Expect = 0.80
Identities = 31/128 (24%), Positives = 61/128 (47%), Gaps = 10/128 (7%)
Frame = +2
Query: 200 VNEEVRELQKKLAQVEED--------LILNKNKLEQANKDLEEKEKQLTATEAEVAALNR 355
+ E + LQ+ LAQ+E + L L K+++ + L++ E++ + + L+
Sbjct: 1745 LQERLGSLQRALAQLEAEKREVERSALRLEKDRV-ALRRTLDKVEREKLRSHEDTVRLSA 1803
Query: 356 KVQQIEEDLEKSEERSGTAQQKL--LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQL 529
+ +++ L +E AQ+++ LEAQ E + LE AQQ + + Q +L
Sbjct: 1804 EKGRLDRTLTGAELELAEAQRQIQQLEAQVVVLEQSHSPAQLEVDAQQQQLELQQEVERL 1863
Query: 530 KEARLLAE 553
+ A+ E
Sbjct: 1864 RSAQAQTE 1871
Score = 31.1 bits (67), Expect = 4.3
Identities = 27/96 (28%), Positives = 44/96 (45%), Gaps = 3/96 (3%)
Frame = +2
Query: 173 RDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKL--EQANKDLEEKEKQLTATEAEVAA 346
R A RAE E+ LQ +L + D +L + L +Q DL++ + TE +A
Sbjct: 249 RLAESRAEAALEKQALLQAQLEEQLRDKVLREKDLAQQQMQSDLDKADLSARVTELGLAV 308
Query: 347 LNRKVQQIEED-LEKSEERSGTAQQKLLEAQQSADE 451
+ Q +E+D + K A + L +Q+A E
Sbjct: 309 KRLEKQNLEKDQVNKDLTEKLEALESLRLQEQAALE 344
>X97053-1|CAA65765.1| 566|Homo sapiens plectin protein.
Length = 566
Score = 53.6 bits (123), Expect = 7e-07
Identities = 46/193 (23%), Positives = 87/193 (45%), Gaps = 2/193 (1%)
Frame = +2
Query: 128 KDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEK 307
+ NA D + EQ +A + + EE R ++ +V++ L + Q LEE
Sbjct: 196 RSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEV 255
Query: 308 EKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKV--LEN 481
E+ +A V R ++ E++ + + + A QK L+A++ A K L+
Sbjct: 256 ER----LKANVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQ 311
Query: 482 RAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISX 661
QQ++ +DQL + + AR AE+A+ + R+ A ++E AE R+K + +
Sbjct: 312 TLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQARRQVEEAE-RLKQSAEEQAQ 370
Query: 662 LEXELKVVGNSLK 700
+ + L+
Sbjct: 371 ARAQAQAAAEKLR 383
Score = 31.9 bits (69), Expect = 2.4
Identities = 28/140 (20%), Positives = 59/140 (42%), Gaps = 2/140 (1%)
Frame = +2
Query: 125 EKDNAMDKADTCEQQARDAN-LRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLE 301
++ A+++ + + +A LR E R+LQ ++ L + A + E
Sbjct: 247 QRKAALEEVERLKANVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKE 306
Query: 302 EKEKQLTATEAEVA-ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLE 478
++ +Q E V L + + E++EE A+++ +A++ +E R+ + E
Sbjct: 307 QELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQARRQVEEAERLKQSAE 366
Query: 479 NRAQQDEERMDQLTNQLKEA 538
+AQ + KEA
Sbjct: 367 EQAQARAQAQAAAEKLRKEA 386
Score = 31.1 bits (67), Expect = 4.3
Identities = 29/158 (18%), Positives = 61/158 (38%), Gaps = 1/158 (0%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
Q A M+ KK + +K + T Q + + + ++EE++ L+ + +
Sbjct: 405 QAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAA 464
Query: 248 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAAL-NRKVQQIEEDLEKSEERSGTAQQKL 424
+ +L +EE K EAE AL R + L++ E+ ++
Sbjct: 465 RQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEA 524
Query: 425 LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEA 538
+A E R+ ++ E Q +++ + +A
Sbjct: 525 ARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQA 562
>X64838-1|CAA46050.1| 1427|Homo sapiens restin protein.
Length = 1427
Score = 53.6 bits (123), Expect = 7e-07
Identities = 41/216 (18%), Positives = 95/216 (43%), Gaps = 8/216 (3%)
Frame = +2
Query: 86 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 265
++A +K+++ +++EK+ KA + ++ + L+ + E + E+ + +E++L +
Sbjct: 786 LEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQIL 845
Query: 266 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 445
K K +A+++ ++ + T ++ + + DLEK E + K E +
Sbjct: 846 KEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDERE 905
Query: 446 DENNRMCKVLENR----AQQDEERMDQLTNQLKEARLLAEDADG---KSDEVSRKLAFVE 604
++ + + LEN + + QLT E RL D + K + + +F++
Sbjct: 906 EQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQ 965
Query: 605 DELEVAEDRVKSGDAKISXL-EXELKVVGNSLKSLE 709
+E + + + + E E K + L LE
Sbjct: 966 KSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLE 1001
Score = 47.2 bits (107), Expect = 6e-05
Identities = 67/239 (28%), Positives = 102/239 (42%), Gaps = 20/239 (8%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVR--------EL 223
QQ+AA +KK KL + K +T Q ++ R E+ E + L
Sbjct: 979 QQEAAKKHEEEKKELERKLS--DLEKKMETSHNQCQELKARYERATSETKTKHEEILQNL 1036
Query: 224 QKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERS 403
QK L E+ L + + ++LEE KQ A +A+ A QI E + K E++
Sbjct: 1037 QKTLLDTEDKLKGAREENSGLLQELEELRKQ--ADKAKAAQTAEDAMQIMEQMTK--EKT 1092
Query: 404 GTAQQKLLEAQQSADENNRMCKVLENRAQQDEE---RMDQLT--NQ-----LKEARLLAE 553
T Q +A N + + EN + EE + LT NQ KE L +
Sbjct: 1093 ETLASLEDTKQTNAKLQNELDTLKENNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQ 1152
Query: 554 DADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKIS--XLEXELKVVGNSLKSLEVSEXK 724
A KS ++S A E+ +++AE+ +S D S LE E V+ N L ++ E K
Sbjct: 1153 AAAQKSQQLS---ALQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKRESK 1208
Score = 35.9 bits (79), Expect = 0.15
Identities = 43/197 (21%), Positives = 82/197 (41%)
Frame = +2
Query: 47 FNSTGP*QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQ 226
F ST P + KA + + A L++ + + A + R + + E
Sbjct: 283 FPSTTPAKAKANAVRRVMATTSA-SLKRSPSASSLSSMSSVASSVSSRPSRTGL-LTETS 340
Query: 227 KKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSG 406
+ A+ + L++ + +E+ + AEVA V +IE++L + R G
Sbjct: 341 SRYARKISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALA--RDG 398
Query: 407 TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSR 586
Q +LE + D+ M + D E+++ L NQL+E + ED + +E S
Sbjct: 399 H-DQHVLELEAKMDQLRTMVEAA------DREKVE-LLNQLEEEKRKVEDLQFRVEEESI 450
Query: 587 KLAFVEDELEVAEDRVK 637
+E + ++ R+K
Sbjct: 451 TKGDLETQTKLEHARIK 467
Score = 35.1 bits (77), Expect = 0.26
Identities = 48/186 (25%), Positives = 78/186 (41%), Gaps = 5/186 (2%)
Frame = +2
Query: 188 RAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQ 367
R E +E++ L ++ ++ K+KLE ANK E + ++++ QQ
Sbjct: 569 REETHQKEIKALYTATEKLSKENESLKSKLEHANK---ENSDVIALWKSKLETAIASHQQ 625
Query: 368 IEEDLEKSEERS-GTAQQKLLEAQQSADENNRMCK-VLEN-RAQQDEERMDQLTNQLKEA 538
E+L+ S + GT + E + ++ + +EN + QQD ER KE
Sbjct: 626 AMEELKVSFSKGLGTETAEFAELKTQIEKMRLDYQHEIENLQNQQDSER----AAHAKEM 681
Query: 539 RLLAEDADGKSDEVSRKLAFVEDELEVAEDR--VKSGDAKISXLEXELKVVGNSLKSLEV 712
L E L + +L+ AED+ V+ D E E+KV K LEV
Sbjct: 682 EALRAKLMKVIKEKENSLEAIRSKLDKAEDQHLVEMEDTLNKLQEAEIKV-----KELEV 736
Query: 713 SEXKAN 730
+ K N
Sbjct: 737 LQAKCN 742
>U63610-1|AAB05428.1| 4574|Homo sapiens plectin protein.
Length = 4574
Score = 53.6 bits (123), Expect = 7e-07
Identities = 46/193 (23%), Positives = 87/193 (45%), Gaps = 2/193 (1%)
Frame = +2
Query: 128 KDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEK 307
+ NA D + EQ +A + + EE R ++ +V++ L + Q LEE
Sbjct: 1979 RSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEV 2038
Query: 308 EKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKV--LEN 481
E+ +A V R ++ E++ + + + A QK L+A++ A K L+
Sbjct: 2039 ER----LKANVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQ 2094
Query: 482 RAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISX 661
QQ++ +DQL + + AR AE+A+ + R+ A ++E AE R+K + +
Sbjct: 2095 TLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQARRQVEEAE-RLKQSAEEQAQ 2153
Query: 662 LEXELKVVGNSLK 700
+ + L+
Sbjct: 2154 ARAQAQAAAEKLR 2166
Score = 42.7 bits (96), Expect = 0.001
Identities = 43/184 (23%), Positives = 84/184 (45%), Gaps = 9/184 (4%)
Frame = +2
Query: 95 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQ-----VEEDLI 259
+++ +Q + ++A+ QQ +A E+ E+ Q K + ++ + +
Sbjct: 1619 LERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEV 1678
Query: 260 LNKNKLEQANKDLEEKEKQLTAT---EAEVAALNRKVQQIEEDLEKSEERS-GTAQQKLL 427
+ L QA + +++E + A +AE A+ ++ + E++LEK + + GTAQQ+L
Sbjct: 1679 AQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQR-ELAEQELEKQRQLAEGTAQQRLA 1737
Query: 428 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 607
Q+ L +Q E++ L +L + A A K E+ +LA V
Sbjct: 1738 AEQELIR--------LRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRA 1789
Query: 608 ELEV 619
E+EV
Sbjct: 1790 EMEV 1793
Score = 37.5 bits (83), Expect = 0.049
Identities = 46/214 (21%), Positives = 91/214 (42%), Gaps = 12/214 (5%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
Q A M+ KK + +K + T Q + + + ++EE++ L+ + +
Sbjct: 2188 QAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAA 2247
Query: 248 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAAL-----NRKVQQIEEDLEKSEE----- 397
+ +L +EE K EAE AL + + ++E+ EK ++
Sbjct: 2248 RQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEA 2307
Query: 398 -RSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLK-EARLLAEDADGKS 571
R A Q+ +Q A+E+ + L + +++ + Q +LK EA LL + + +
Sbjct: 2308 ARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKE-LA 2366
Query: 572 DEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXE 673
E +R+L ED+ ++A+ + LE E
Sbjct: 2367 QEQARRLQ--EDKEQMAQQLAEETQGFQRTLEAE 2398
Score = 37.5 bits (83), Expect = 0.049
Identities = 33/147 (22%), Positives = 71/147 (48%), Gaps = 5/147 (3%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQ---ARDANLRAEKVNEEVRELQKKLA 238
QQ+A + ++MQ ++ E+ + + +Q +D+ L+ E+ E+ + KL
Sbjct: 2490 QQEAKLLQLKSEEMQTVQQEQ--LLQETQALQQSFLSEKDSLLQRERFIEQEKA---KLE 2544
Query: 239 QVEEDLILNKNKL-EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLE-KSEERSGTA 412
Q+ +D + +L E+ + ++ E++ A + R+ + EE + K EE
Sbjct: 2545 QLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLE 2604
Query: 413 QQKLLEAQQSADENNRMCKVLENRAQQ 493
QQ+ + + A+EN R+ + L+ +Q
Sbjct: 2605 QQRRQQEELLAEENQRLREQLQLLEEQ 2631
Score = 37.1 bits (82), Expect = 0.065
Identities = 30/131 (22%), Positives = 63/131 (48%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
+ +A + +K ++ E+ +KA EQ +D +A+++ EE + Q+++ Q
Sbjct: 2514 ETQALQQSFLSEKDSLLQRERFIEQEKAKL-EQLFQDEVAKAQQLREEQQRQQQQMEQER 2572
Query: 248 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 427
+ L+ + +E+A + E E+ + + E+ QQ+E+ + EE Q+L
Sbjct: 2573 QRLVAS---MEEARRRQHEAEEGVRRKQEEL-------QQLEQQRRQQEELLAEENQRLR 2622
Query: 428 EAQQSADENNR 460
E Q +E +R
Sbjct: 2623 EQLQLLEEQHR 2633
Score = 31.9 bits (69), Expect = 2.4
Identities = 28/140 (20%), Positives = 59/140 (42%), Gaps = 2/140 (1%)
Frame = +2
Query: 125 EKDNAMDKADTCEQQARDAN-LRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLE 301
++ A+++ + + +A LR E R+LQ ++ L + A + E
Sbjct: 2030 QRKAALEEVERLKANVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKE 2089
Query: 302 EKEKQLTATEAEVA-ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLE 478
++ +Q E V L + + E++EE A+++ +A++ +E R+ + E
Sbjct: 2090 QELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQARRQVEEAERLKQSAE 2149
Query: 479 NRAQQDEERMDQLTNQLKEA 538
+AQ + KEA
Sbjct: 2150 EQAQARAQAQAAAEKLRKEA 2169
>U53204-1|AAB05427.1| 4574|Homo sapiens plectin protein.
Length = 4574
Score = 53.6 bits (123), Expect = 7e-07
Identities = 46/193 (23%), Positives = 87/193 (45%), Gaps = 2/193 (1%)
Frame = +2
Query: 128 KDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEK 307
+ NA D + EQ +A + + EE R ++ +V++ L + Q LEE
Sbjct: 1979 RSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEV 2038
Query: 308 EKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKV--LEN 481
E+ +A V R ++ E++ + + + A QK L+A++ A K L+
Sbjct: 2039 ER----LKANVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQ 2094
Query: 482 RAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISX 661
QQ++ +DQL + + AR AE+A+ + R+ A ++E AE R+K + +
Sbjct: 2095 TLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQARRQVEEAE-RLKQSAEEQAQ 2153
Query: 662 LEXELKVVGNSLK 700
+ + L+
Sbjct: 2154 ARAQAQAAAEKLR 2166
Score = 42.7 bits (96), Expect = 0.001
Identities = 43/184 (23%), Positives = 84/184 (45%), Gaps = 9/184 (4%)
Frame = +2
Query: 95 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQ-----VEEDLI 259
+++ +Q + ++A+ QQ +A E+ E+ Q K + ++ + +
Sbjct: 1619 LERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEV 1678
Query: 260 LNKNKLEQANKDLEEKEKQLTAT---EAEVAALNRKVQQIEEDLEKSEERS-GTAQQKLL 427
+ L QA + +++E + A +AE A+ ++ + E++LEK + + GTAQQ+L
Sbjct: 1679 AQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQR-ELAEQELEKQRQLAEGTAQQRLA 1737
Query: 428 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 607
Q+ L +Q E++ L +L + A A K E+ +LA V
Sbjct: 1738 AEQELIR--------LRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRA 1789
Query: 608 ELEV 619
E+EV
Sbjct: 1790 EMEV 1793
Score = 37.5 bits (83), Expect = 0.049
Identities = 46/214 (21%), Positives = 91/214 (42%), Gaps = 12/214 (5%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
Q A M+ KK + +K + T Q + + + ++EE++ L+ + +
Sbjct: 2188 QAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAA 2247
Query: 248 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAAL-----NRKVQQIEEDLEKSEE----- 397
+ +L +EE K EAE AL + + ++E+ EK ++
Sbjct: 2248 RQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEA 2307
Query: 398 -RSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLK-EARLLAEDADGKS 571
R A Q+ +Q A+E+ + L + +++ + Q +LK EA LL + + +
Sbjct: 2308 ARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKE-LA 2366
Query: 572 DEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXE 673
E +R+L ED+ ++A+ + LE E
Sbjct: 2367 QEQARRLQ--EDKEQMAQQLAEETQGFQRTLEAE 2398
Score = 37.5 bits (83), Expect = 0.049
Identities = 33/147 (22%), Positives = 71/147 (48%), Gaps = 5/147 (3%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQ---ARDANLRAEKVNEEVRELQKKLA 238
QQ+A + ++MQ ++ E+ + + +Q +D+ L+ E+ E+ + KL
Sbjct: 2490 QQEAKLLQLKSEEMQTVQQEQ--LLQETQALQQSFLSEKDSLLQRERFIEQEKA---KLE 2544
Query: 239 QVEEDLILNKNKL-EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLE-KSEERSGTA 412
Q+ +D + +L E+ + ++ E++ A + R+ + EE + K EE
Sbjct: 2545 QLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLE 2604
Query: 413 QQKLLEAQQSADENNRMCKVLENRAQQ 493
QQ+ + + A+EN R+ + L+ +Q
Sbjct: 2605 QQRRQQEELLAEENQRLREQLQLLEEQ 2631
Score = 37.1 bits (82), Expect = 0.065
Identities = 30/131 (22%), Positives = 63/131 (48%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
+ +A + +K ++ E+ +KA EQ +D +A+++ EE + Q+++ Q
Sbjct: 2514 ETQALQQSFLSEKDSLLQRERFIEQEKAKL-EQLFQDEVAKAQQLREEQQRQQQQMEQER 2572
Query: 248 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 427
+ L+ + +E+A + E E+ + + E+ QQ+E+ + EE Q+L
Sbjct: 2573 QRLVAS---MEEARRRQHEAEEGVRRKQEEL-------QQLEQQRRQQEELLAEENQRLR 2622
Query: 428 EAQQSADENNR 460
E Q +E +R
Sbjct: 2623 EQLQLLEEQHR 2633
Score = 31.9 bits (69), Expect = 2.4
Identities = 28/140 (20%), Positives = 59/140 (42%), Gaps = 2/140 (1%)
Frame = +2
Query: 125 EKDNAMDKADTCEQQARDAN-LRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLE 301
++ A+++ + + +A LR E R+LQ ++ L + A + E
Sbjct: 2030 QRKAALEEVERLKANVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKE 2089
Query: 302 EKEKQLTATEAEVA-ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLE 478
++ +Q E V L + + E++EE A+++ +A++ +E R+ + E
Sbjct: 2090 QELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQARRQVEEAERLKQSAE 2149
Query: 479 NRAQQDEERMDQLTNQLKEA 538
+AQ + KEA
Sbjct: 2150 EQAQARAQAQAAAEKLRKEA 2169
>M97501-1|AAA35693.1| 1392|Homo sapiens cytoplasmic linker protein-170
alpha-2 protein.
Length = 1392
Score = 53.6 bits (123), Expect = 7e-07
Identities = 41/216 (18%), Positives = 95/216 (43%), Gaps = 8/216 (3%)
Frame = +2
Query: 86 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 265
++A +K+++ +++EK+ KA + ++ + L+ + E + E+ + +E++L +
Sbjct: 751 LEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQIL 810
Query: 266 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 445
K K +A+++ ++ + T ++ + + DLEK E + K E +
Sbjct: 811 KEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDERE 870
Query: 446 DENNRMCKVLENR----AQQDEERMDQLTNQLKEARLLAEDADG---KSDEVSRKLAFVE 604
++ + + LEN + + QLT E RL D + K + + +F++
Sbjct: 871 EQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQ 930
Query: 605 DELEVAEDRVKSGDAKISXL-EXELKVVGNSLKSLE 709
+E + + + + E E K + L LE
Sbjct: 931 KSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLE 966
Score = 47.2 bits (107), Expect = 6e-05
Identities = 67/239 (28%), Positives = 102/239 (42%), Gaps = 20/239 (8%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVR--------EL 223
QQ+AA +KK KL + K +T Q ++ R E+ E + L
Sbjct: 944 QQEAAKKHEEEKKELERKLS--DLEKKMETSHNQCQELKARYERATSETKTKHEEILQNL 1001
Query: 224 QKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERS 403
QK L E+ L + + ++LEE KQ A +A+ A QI E + K E++
Sbjct: 1002 QKTLLDTEDKLKGAREENSGLLQELEELRKQ--AEKAKAAQTAEDAMQIMEQMTK--EKT 1057
Query: 404 GTAQQKLLEAQQSADENNRMCKVLENRAQQDEE---RMDQLT--NQ-----LKEARLLAE 553
T Q +A N + + EN + EE + LT NQ KE L +
Sbjct: 1058 ETLASLEDTKQTNAKLQNELDTLKENNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQ 1117
Query: 554 DADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKIS--XLEXELKVVGNSLKSLEVSEXK 724
A KS ++S A E+ +++AE+ +S D S LE E V+ N L ++ E K
Sbjct: 1118 AAAQKSQQLS---ALQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKRESK 1173
Score = 35.5 bits (78), Expect = 0.20
Identities = 33/131 (25%), Positives = 62/131 (47%), Gaps = 6/131 (4%)
Frame = +2
Query: 311 KQLTATEAEVAALNRKVQQIEE-----DLEKSEERSGTAQQKLLEAQQSADENNRMCKVL 475
++++ T A AL K Q IE+ DLE++E T+ +E + + + VL
Sbjct: 345 RKISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALARDGHDQHVL 404
Query: 476 ENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED-ELEVAEDRVKSGDAK 652
E E +MDQL ++ A + + +E RK VED + V E+ + GD +
Sbjct: 405 EL-----EAKMDQLRTMVEAADREKVELLNQLEEEKRK---VEDLQFRVEEESITKGDLE 456
Query: 653 ISXLEXELKVV 685
++ + + +++
Sbjct: 457 VATVSEKSRIM 467
Score = 35.1 bits (77), Expect = 0.26
Identities = 48/186 (25%), Positives = 78/186 (41%), Gaps = 5/186 (2%)
Frame = +2
Query: 188 RAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQ 367
R E +E++ L ++ ++ K+KLE ANK E + ++++ QQ
Sbjct: 534 REETHQKEIKALYTATEKLSKENESLKSKLEHANK---ENSDVIALWKSKLETAIASHQQ 590
Query: 368 IEEDLEKSEERS-GTAQQKLLEAQQSADENNRMCK-VLEN-RAQQDEERMDQLTNQLKEA 538
E+L+ S + GT + E + ++ + +EN + QQD ER KE
Sbjct: 591 AMEELKVSFSKGLGTETAEFAELKTQIEKMRLDYQHEIENLQNQQDSER----AAHAKEM 646
Query: 539 RLLAEDADGKSDEVSRKLAFVEDELEVAEDR--VKSGDAKISXLEXELKVVGNSLKSLEV 712
L E L + +L+ AED+ V+ D E E+KV K LEV
Sbjct: 647 EALRAKLMKVIKEKENSLEAIRSKLDKAEDQHLVEMEDTLNKLQEAEIKV-----KELEV 701
Query: 713 SEXKAN 730
+ K N
Sbjct: 702 LQAKCN 707
>BC126305-1|AAI26306.1| 1438|Homo sapiens CLIP1 protein protein.
Length = 1438
Score = 53.6 bits (123), Expect = 7e-07
Identities = 41/216 (18%), Positives = 95/216 (43%), Gaps = 8/216 (3%)
Frame = +2
Query: 86 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 265
++A +K+++ +++EK+ KA + ++ + L+ + E + E+ + +E++L +
Sbjct: 797 LEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQIL 856
Query: 266 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 445
K K +A+++ ++ + T ++ + + DLEK E + K E +
Sbjct: 857 KEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDERE 916
Query: 446 DENNRMCKVLENR----AQQDEERMDQLTNQLKEARLLAEDADG---KSDEVSRKLAFVE 604
++ + + LEN + + QLT E RL D + K + + +F++
Sbjct: 917 EQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQ 976
Query: 605 DELEVAEDRVKSGDAKISXL-EXELKVVGNSLKSLE 709
+E + + + + E E K + L LE
Sbjct: 977 KSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLE 1012
Score = 47.2 bits (107), Expect = 6e-05
Identities = 67/239 (28%), Positives = 102/239 (42%), Gaps = 20/239 (8%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVR--------EL 223
QQ+AA +KK KL + K +T Q ++ R E+ E + L
Sbjct: 990 QQEAAKKHEEEKKELERKLS--DLEKKMETSHNQCQELKARYERATSETKTKHEEILQNL 1047
Query: 224 QKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERS 403
QK L E+ L + + ++LEE KQ A +A+ A QI E + K E++
Sbjct: 1048 QKTLLDTEDKLKGAREENSGLLQELEELRKQ--ADKAKAAQTAEDAMQIMEQMTK--EKT 1103
Query: 404 GTAQQKLLEAQQSADENNRMCKVLENRAQQDEE---RMDQLT--NQ-----LKEARLLAE 553
T Q +A N + + EN + EE + LT NQ KE L +
Sbjct: 1104 ETLASLEDTKQTNAKLQNELDTLKENNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQ 1163
Query: 554 DADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKIS--XLEXELKVVGNSLKSLEVSEXK 724
A KS ++S A E+ +++AE+ +S D S LE E V+ N L ++ E K
Sbjct: 1164 AAAQKSQQLS---ALQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKRESK 1219
Score = 39.5 bits (88), Expect = 0.012
Identities = 49/214 (22%), Positives = 90/214 (42%), Gaps = 4/214 (1%)
Frame = +2
Query: 47 FNSTGP*QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQ 226
F ST P + KA + + A L++ + + A + R + + E
Sbjct: 283 FPSTTPAKAKANAVRRVMATTSA-SLKRSPSASSLSSMSSVASSVSSRPSRTGL-LTETS 340
Query: 227 KKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSG 406
+ A+ + L++ + +E+ + AEVA V +IE++L + R G
Sbjct: 341 SRYARKISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALA--RDG 398
Query: 407 TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSR 586
Q +LE + D+ M + D E+++ L NQL+E + ED + +E S
Sbjct: 399 H-DQHVLELEAKMDQLRTMVEAA------DREKVE-LLNQLEEEKRKVEDLQFRVEEESI 450
Query: 587 KLAFVEDELEVAED----RVKSGDAKISXLEXEL 676
+E + +++ED + K A+I LE L
Sbjct: 451 TKGDLEQKSQISEDPENTQTKLEHARIKELEQSL 484
Score = 35.1 bits (77), Expect = 0.26
Identities = 48/186 (25%), Positives = 78/186 (41%), Gaps = 5/186 (2%)
Frame = +2
Query: 188 RAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQ 367
R E +E++ L ++ ++ K+KLE ANK E + ++++ QQ
Sbjct: 580 REETHQKEIKALYTATEKLSKENESLKSKLEHANK---ENSDVIALWKSKLETAIASHQQ 636
Query: 368 IEEDLEKSEERS-GTAQQKLLEAQQSADENNRMCK-VLEN-RAQQDEERMDQLTNQLKEA 538
E+L+ S + GT + E + ++ + +EN + QQD ER KE
Sbjct: 637 AMEELKVSFSKGLGTETAEFAELKTQIEKMRLDYQHEIENLQNQQDSER----AAHAKEM 692
Query: 539 RLLAEDADGKSDEVSRKLAFVEDELEVAEDR--VKSGDAKISXLEXELKVVGNSLKSLEV 712
L E L + +L+ AED+ V+ D E E+KV K LEV
Sbjct: 693 EALRAKLMKVIKEKENSLEAIRSKLDKAEDQHLVEMEDTLNKLQEAEIKV-----KELEV 747
Query: 713 SEXKAN 730
+ K N
Sbjct: 748 LQAKCN 753
>BC114213-1|AAI14214.1| 1392|Homo sapiens CAP-GLY domain containing
linker protein 1 protein.
Length = 1392
Score = 53.6 bits (123), Expect = 7e-07
Identities = 41/216 (18%), Positives = 95/216 (43%), Gaps = 8/216 (3%)
Frame = +2
Query: 86 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 265
++A +K+++ +++EK+ KA + ++ + L+ + E + E+ + +E++L +
Sbjct: 751 LEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQIL 810
Query: 266 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 445
K K +A+++ ++ + T ++ + + DLEK E + K E +
Sbjct: 811 KEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDERE 870
Query: 446 DENNRMCKVLENR----AQQDEERMDQLTNQLKEARLLAEDADG---KSDEVSRKLAFVE 604
++ + + LEN + + QLT E RL D + K + + +F++
Sbjct: 871 EQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQ 930
Query: 605 DELEVAEDRVKSGDAKISXL-EXELKVVGNSLKSLE 709
+E + + + + E E K + L LE
Sbjct: 931 KSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLE 966
Score = 47.2 bits (107), Expect = 6e-05
Identities = 67/239 (28%), Positives = 102/239 (42%), Gaps = 20/239 (8%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVR--------EL 223
QQ+AA +KK KL + K +T Q ++ R E+ E + L
Sbjct: 944 QQEAAKKHEEEKKELERKLS--DLEKKMETSHNQCQELKARYERATSETKTKHEEILQNL 1001
Query: 224 QKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERS 403
QK L E+ L + + ++LEE KQ A +A+ A QI E + K E++
Sbjct: 1002 QKTLLDTEDKLKGAREENSGLLQELEELRKQ--ADKAKAAQTAEDAMQIMEQMTK--EKT 1057
Query: 404 GTAQQKLLEAQQSADENNRMCKVLENRAQQDEE---RMDQLT--NQ-----LKEARLLAE 553
T Q +A N + + EN + EE + LT NQ KE L +
Sbjct: 1058 ETLASLEDTKQTNAKLQNELDTLKENNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQ 1117
Query: 554 DADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKIS--XLEXELKVVGNSLKSLEVSEXK 724
A KS ++S A E+ +++AE+ +S D S LE E V+ N L ++ E K
Sbjct: 1118 AAAQKSQQLS---ALQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKRESK 1173
Score = 35.5 bits (78), Expect = 0.20
Identities = 33/131 (25%), Positives = 62/131 (47%), Gaps = 6/131 (4%)
Frame = +2
Query: 311 KQLTATEAEVAALNRKVQQIEE-----DLEKSEERSGTAQQKLLEAQQSADENNRMCKVL 475
++++ T A AL K Q IE+ DLE++E T+ +E + + + VL
Sbjct: 345 RKISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALARDGHDQHVL 404
Query: 476 ENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED-ELEVAEDRVKSGDAK 652
E E +MDQL ++ A + + +E RK VED + V E+ + GD +
Sbjct: 405 EL-----EAKMDQLRTMVEAADREKVELLNQLEEEKRK---VEDLQFRVEEESITKGDLE 456
Query: 653 ISXLEXELKVV 685
++ + + +++
Sbjct: 457 VATVSEKSRIM 467
Score = 34.3 bits (75), Expect = 0.46
Identities = 43/183 (23%), Positives = 76/183 (41%), Gaps = 2/183 (1%)
Frame = +2
Query: 188 RAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQ 367
R E +E++ L ++ ++ K+KLE ANK E + ++++ QQ
Sbjct: 534 REETHQKEIKALYTATEKLSKENESLKSKLEHANK---ENSDVIALWKSKLETAIASHQQ 590
Query: 368 IEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLL 547
E+L+ S + A+ ++ E R+ E Q+++ ++ + KE L
Sbjct: 591 AMEELKVSFSKGLGAETAEFAELKTQIEKMRLDYQHEIENLQNQQNSERAAH-AKEMEAL 649
Query: 548 AEDADGKSDEVSRKLAFVEDELEVAEDR--VKSGDAKISXLEXELKVVGNSLKSLEVSEX 721
E L + +L+ AED+ V+ D E E+KV K LEV +
Sbjct: 650 RAKLMKVIKEKENSLEAIRSKLDKAEDQHLVEMEDTLNKLQEAEIKV-----KELEVLQA 704
Query: 722 KAN 730
K N
Sbjct: 705 KCN 707
>AY681966-1|AAV87216.1| 2069|Homo sapiens citron protein.
Length = 2069
Score = 53.6 bits (123), Expect = 7e-07
Identities = 49/216 (22%), Positives = 103/216 (47%), Gaps = 1/216 (0%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
Q+ A ++ ++ M ++ + +A ++D E + R++ L AE+ + E Q KL + +
Sbjct: 555 QEYQAQVEEMRLMMNQLEEDLVSARRRSDLYESELRESRLAAEEFKRKATECQHKLLKAK 614
Query: 248 EDLILNKNKL-EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL 424
+ K ++ E A + E+QL K+Q+++E LEK+ + S A + L
Sbjct: 615 DQ---GKPEVGEYAKLEKINAEQQL------------KIQELQEKLEKAVKASTEATELL 659
Query: 425 LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVE 604
+Q+ + R + L+NR E +L + +E R E+ + + + R+ ++
Sbjct: 660 QNIRQAKERAERELEKLQNREDSSEGIRKKLV-EAEERRHSLENKVKRLETMERRENRLK 718
Query: 605 DELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEV 712
D+++ +++ KI LE + + S + LEV
Sbjct: 719 DDIQTKSQQIQQMADKILELEEKHREAQVSAQHLEV 754
Score = 51.6 bits (118), Expect = 3e-06
Identities = 39/177 (22%), Positives = 74/177 (41%)
Frame = +2
Query: 80 ATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLI 259
A +++KK+ E ++ DK EQ+ + R +V + + + +L E
Sbjct: 442 AKTSSMEKKLLIKSKELQDSQDKCHKMEQEMTRLHRRVSEVEAVLSQKEVELKASETQRS 501
Query: 260 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 439
L + L + ++ L EV+ + K Q+ D+ + + +++ E Q
Sbjct: 502 LLEQDLATYITECSSLKRSLEQARMEVSQEDDKALQLLHDIREQSRKLQEIKEQ--EYQA 559
Query: 440 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDE 610
+E M LE R D ++L+E+RL AE+ K+ E KL +D+
Sbjct: 560 QVEEMRLMMNQLEEDLVSARRRSDLYESELRESRLAAEEFKRKATECQHKLLKAKDQ 616
Score = 51.2 bits (117), Expect = 4e-06
Identities = 49/183 (26%), Positives = 85/183 (46%), Gaps = 18/183 (9%)
Frame = +2
Query: 86 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEE-------VRELQKKLAQV 244
M A ++ + ++ +K +A E Q R + EK++ + + EL+ +L +V
Sbjct: 844 MKAQEEMISELRQQKFYLETQAGKLEAQNRKLEEQLEKISHQDHSDKNRLLELETRLREV 903
Query: 245 ----EEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTA 412
EE + K +L + L+E+E QLTA +A AAL +++Q + +LE++ +
Sbjct: 904 SLEHEEQKLELKRQLTELQLSLQERESQLTALQAARAALESQLRQAKTELEETTAEAEEE 963
Query: 413 QQKLL----EAQQSADENNRMCKV---LENRAQQDEERMDQLTNQLKEARLLAEDADGKS 571
Q L E Q+ D C V LE + Q E +L NQ ++A G +
Sbjct: 964 IQALTAHRDEIQRKFDALRNSCTVITDLEEQLNQLTEDNAELNNQNFYLSKQLDEASGAN 1023
Query: 572 DEV 580
DE+
Sbjct: 1024 DEI 1026
Score = 49.6 bits (113), Expect = 1e-05
Identities = 50/204 (24%), Positives = 93/204 (45%), Gaps = 12/204 (5%)
Frame = +2
Query: 119 KLEKD-NAMDKADTCEQQARDANLRAEKVNEEVRE-------LQKKLAQVEEDLILNKNK 274
KLEK A +A Q R A RAE+ E+++ ++KKL + EE ++
Sbjct: 644 KLEKAVKASTEATELLQNIRQAKERAERELEKLQNREDSSEGIRKKLVEAEE----RRHS 699
Query: 275 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDL----EKSEERSGTAQQKLLEAQQS 442
LE K LE E++ + ++ ++++QQ+ + + EK E +AQ + +Q
Sbjct: 700 LENKVKRLETMERRENRLKDDIQTKSQQIQQMADKILELEEKHREAQVSAQHLEVHLKQK 759
Query: 443 ADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVA 622
KVL+N+ ++D + L N ++ E+A K +S + A +
Sbjct: 760 EQHYEEKIKVLDNQIKKDLADKETLENMMQRHE---EEAHEKGKILSEQKAMI----NAM 812
Query: 623 EDRVKSGDAKISXLEXELKVVGNS 694
+ +++S + +I L K+ NS
Sbjct: 813 DSKIRSLEQRIVELSEANKLAANS 836
Score = 42.7 bits (96), Expect = 0.001
Identities = 47/224 (20%), Positives = 103/224 (45%), Gaps = 12/224 (5%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
Q A D I++K A++ D + Q D N N + + + +
Sbjct: 965 QALTAHRDEIQRKFDALRNSCTVITDLEEQLNQLTED-NAELNNQNFYLSKQLDEASGAN 1023
Query: 248 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEE---DLEKSEERSGTAQQ 418
++++ +++++ +++ E+E QLT+ + + AL +EE DLE + ++
Sbjct: 1024 DEIVQLRSEVDHLRREITEREMQLTSQKQTMEALKTTCTMLEEQVMDLEALNDEL-LEKE 1082
Query: 419 KLLEAQQS--ADENNRM-CKVLENRAQQDEERMD--QLTNQLKEARLLAEDA--DGKSDE 577
+ EA +S DE ++ C+V E + D E+ + ++ E+R + E A + K++
Sbjct: 1083 RQWEAWRSVLGDEKSQFECRVRELQRMLDTEKQSRARADQRITESRQVVELAVKEHKAEI 1142
Query: 578 VSRKLAFVEDEL--EVAEDRVKSGDAKISXLEXELKVVGNSLKS 703
++ + A E +L E D++ + K + LE + + L++
Sbjct: 1143 LALQQALKEQKLKAESLSDKLNDLEKKHAMLEMNARSLQQKLET 1186
Score = 39.5 bits (88), Expect = 0.012
Identities = 49/233 (21%), Positives = 103/233 (44%), Gaps = 30/233 (12%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEK-----VNEEVRELQKK 232
++K +D KK A K +N M + + E + L +K ++ ++R L+++
Sbjct: 764 EEKIKVLDNQIKKDLADKETLENMMQRHEE-EAHEKGKILSEQKAMINAMDSKIRSLEQR 822
Query: 233 LAQVEE--DLILNKNKLEQANKDLEEK-----EKQLTATEAEVAALNRKVQQIEEDLEKS 391
+ ++ E L N + Q N +E+ +Q E + L + +++EE LEK
Sbjct: 823 IVELSEANKLAANSSLFTQRNMKAQEEMISELRQQKFYLETQAGKLEAQNRKLEEQLEKI 882
Query: 392 EERSGTAQQKLLEAQ--------QSADENNRMCKVLENRAQQDEERMDQLT--------- 520
+ + + +LLE + + ++ + + L +ER QLT
Sbjct: 883 SHQDHSDKNRLLELETRLREVSLEHEEQKLELKRQLTELQLSLQERESQLTALQAARAAL 942
Query: 521 -NQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXEL 676
+QL++A+ E+ +++E + L DE++ D +++ I+ LE +L
Sbjct: 943 ESQLRQAKTELEETTAEAEEEIQALTAHRDEIQRKFDALRNSCTVITDLEEQL 995
Score = 34.7 bits (76), Expect = 0.35
Identities = 25/113 (22%), Positives = 55/113 (48%), Gaps = 4/113 (3%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
Q +A I + Q ++L + +Q ++ L+AE +++++ +L+KK A +E
Sbjct: 1115 QSRARADQRITESRQVVELAVKEHKAEILALQQALKEQKLKAESLSDKLNDLEKKHAMLE 1174
Query: 248 EDLILNKNKLEQ----ANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSE 394
+ + KLE + LEE+ K + + + R Q ++E L++++
Sbjct: 1175 MNARSLQQKLETERELKQRLLEEQAKLQQQMDLQKNHIFRLTQGLQEALDRAD 1227
>AL832009-1|CAD89912.1| 1177|Homo sapiens hypothetical protein
protein.
Length = 1177
Score = 53.6 bits (123), Expect = 7e-07
Identities = 59/230 (25%), Positives = 108/230 (46%), Gaps = 17/230 (7%)
Frame = +2
Query: 74 KAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLA----Q 241
KA T + + + + +KLE D KA Q+ + N + R+L+ KL +
Sbjct: 283 KAITSKSKEDRQKLLKLEVDFE-HKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLTQR 341
Query: 242 VEEDLILNKNKLEQANKDLEEKEKQLTATE-------AEVAALNRKVQQIE---EDLEKS 391
+EE +NKN L++A ++L+E ++ E AEV L ++V ++E E++ K+
Sbjct: 342 IEELEEINKN-LQKAEEELQELRDKIAKGECGNSSLMAEVENLRKRVLEMEGKDEEITKT 400
Query: 392 EERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKS 571
E + ++KL E + + E + L+ R + E+ + + E L + + K
Sbjct: 401 ESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSKSKSECTQLHLNLE-KE 459
Query: 572 DEVSRKLAFVEDELEVAEDRVKS---GDAKISXLEXELKVVGNSLKSLEV 712
+++ L +ELEV + RVK ++++ E LK LKS V
Sbjct: 460 KNLTKDLL---NELEVVKSRVKELECSESRLEKAELSLKDDLTKLKSFTV 506
Score = 44.4 bits (100), Expect = 4e-04
Identities = 42/186 (22%), Positives = 93/186 (50%), Gaps = 7/186 (3%)
Frame = +2
Query: 80 ATMDAIKKKMQAMKLEKDNAMDKADT-CEQ---QARDANLRAEKVNEEVRELQKKLAQVE 247
A ++ ++K++ M+ KD + K ++ C + + ++ ++++ EV +LQK+++++E
Sbjct: 378 AEVENLRKRVLEME-GKDEEITKTESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELE 436
Query: 248 E-DLILNKNKLEQANKDLE-EKEKQLTATEA-EVAALNRKVQQIEEDLEKSEERSGTAQQ 418
+ + +K+K E L EKEK LT E+ + +V+++E + E+ + +
Sbjct: 437 KLEEAFSKSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKAELSLKD 496
Query: 419 KLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAF 598
L + + K + + +Q+E ++D L K + D K E S+KL
Sbjct: 497 DLTKLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLK 556
Query: 599 VEDELE 616
++ E+E
Sbjct: 557 LKSEME 562
Score = 44.0 bits (99), Expect = 6e-04
Identities = 46/189 (24%), Positives = 84/189 (44%), Gaps = 6/189 (3%)
Frame = +2
Query: 176 DANLRAEKVNEEVRELQKKLAQVE---EDLILNKNKLEQANKDLEEKEKQLTATEAEVAA 346
D +A + ++E E+ KLA E L L L Q ++LEE K L E E+
Sbjct: 302 DFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLTQRIEELEEINKNLQKAEEELQE 361
Query: 347 LNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQ 526
L K+ + E ++++LE + +E + E++ ++ +++ + +
Sbjct: 362 LRDKIAKGECGNSSLMAEVENLRKRVLEMEGKDEEITK----TESQCRELRKKLQEEEHH 417
Query: 527 LKEARLLAEDADGKSDEVSR-KLAFVEDELEVAEDRVKSGDAK--ISXLEXELKVVGNSL 697
KE RL E + E+ + + AF + + E + + K L EL+VV + +
Sbjct: 418 SKELRLEVEKLQKRMSELEKLEEAFSKSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRV 477
Query: 698 KSLEVSEXK 724
K LE SE +
Sbjct: 478 KELECSESR 486
>U38292-1|AAB41133.1| 2805|Homo sapiens microtubule-associated protein
1a protein.
Length = 2805
Score = 53.2 bits (122), Expect = 9e-07
Identities = 56/200 (28%), Positives = 97/200 (48%), Gaps = 4/200 (2%)
Frame = +2
Query: 122 LEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLE 301
LE ++ DT Q +D L + NE V++ K L Q DL LEQ +K LE
Sbjct: 1374 LEHKEVVEPKDTAIYQ-KDEALHVK--NEAVKQQXKALEQKGRDLEQXDTALEQKDKALE 1430
Query: 302 EKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN-NRMCKVLE 478
K+K L E + AL +K +I + +K+ E+ TA ++ +A + D++ + +VLE
Sbjct: 1431 PKDKDL---EXKDKALEQK-DKIPXEKDKALEQKDTALEQKDKALEPKDKDLEQKDRVLE 1486
Query: 479 NRAQQDEERMDQLTNQLKEARLLA-ED--ADGKSDEVSRKLAFVEDELEVAEDRVKSGDA 649
+ + EE+ L +++ A ED A+ K ++ + E + + E + K +
Sbjct: 1487 QKEKIPEEKDKALDQKVRSVEHKAPEDTVAEMKDRDLEQTDKAPEQKHQAQEQKDKVSEK 1546
Query: 650 KISXLEXELKVVGNSLKSLE 709
K LE + +G ++LE
Sbjct: 1547 KDQALEXKYWALGQKDEALE 1566
Score = 37.5 bits (83), Expect = 0.049
Identities = 33/149 (22%), Positives = 72/149 (48%)
Frame = +2
Query: 89 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 268
D + ++ + + EKD A+D Q+ R +A + + V E++ + + + K
Sbjct: 1482 DRVLEQKEKIPEEKDKALD------QKVRSVEHKAPE--DTVAEMKDRDLEQTDKAPEQK 1533
Query: 269 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSAD 448
++ ++ + EK+ Q A E + AL +K + +E +++ EE T +Q+ L +
Sbjct: 1534 HQAQEQKDKVSEKKDQ--ALEXKYWALGQKDEALEXNIQALEENHQTQEQESL----VQE 1587
Query: 449 ENNRMCKVLENRAQQDEERMDQLTNQLKE 535
+ R K+LE ++ + + M++ L E
Sbjct: 1588 DKTRKPKMLEEKSPEKVKAMEEKLEALLE 1616
>U38291-1|AAB41132.1| 2805|Homo sapiens microtubule-associated protein
1a protein.
Length = 2805
Score = 53.2 bits (122), Expect = 9e-07
Identities = 56/200 (28%), Positives = 97/200 (48%), Gaps = 4/200 (2%)
Frame = +2
Query: 122 LEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLE 301
LE ++ DT Q +D L + NE V++ K L Q DL LEQ +K LE
Sbjct: 1374 LEHKEVVEPKDTAIYQ-KDEALHVK--NEAVKQQXKALEQKGRDLEQXDTALEQKDKALE 1430
Query: 302 EKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN-NRMCKVLE 478
K+K L E + AL +K +I + +K+ E+ TA ++ +A + D++ + +VLE
Sbjct: 1431 PKDKDL---EXKDKALEQK-DKIPXEKDKALEQKDTALEQKDKALEPKDKDLEQKDRVLE 1486
Query: 479 NRAQQDEERMDQLTNQLKEARLLA-ED--ADGKSDEVSRKLAFVEDELEVAEDRVKSGDA 649
+ + EE+ L +++ A ED A+ K ++ + E + + E + K +
Sbjct: 1487 QKEKIPEEKDKALDQKVRSVEHKAPEDTVAEMKDRDLEQTDKAPEQKHQAQEQKDKVSEK 1546
Query: 650 KISXLEXELKVVGNSLKSLE 709
K LE + +G ++LE
Sbjct: 1547 KDQALEXKYWALGQKDEALE 1566
Score = 37.5 bits (83), Expect = 0.049
Identities = 33/149 (22%), Positives = 72/149 (48%)
Frame = +2
Query: 89 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 268
D + ++ + + EKD A+D Q+ R +A + + V E++ + + + K
Sbjct: 1482 DRVLEQKEKIPEEKDKALD------QKVRSVEHKAPE--DTVAEMKDRDLEQTDKAPEQK 1533
Query: 269 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSAD 448
++ ++ + EK+ Q A E + AL +K + +E +++ EE T +Q+ L +
Sbjct: 1534 HQAQEQKDKVSEKKDQ--ALEXKYWALGQKDEALEXNIQALEENHQTQEQESL----VQE 1587
Query: 449 ENNRMCKVLENRAQQDEERMDQLTNQLKE 535
+ R K+LE ++ + + M++ L E
Sbjct: 1588 DKTRKPKMLEEKSPEKVKAMEEKLEALLE 1616
>U25725-1|AAA86889.1| 1017|Homo sapiens AH antigen protein.
Length = 1017
Score = 53.2 bits (122), Expect = 9e-07
Identities = 47/236 (19%), Positives = 112/236 (47%), Gaps = 28/236 (11%)
Frame = +2
Query: 89 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 268
D++K K++ ++ E + + + A ++ E + ++ E+ + L E DL+ +
Sbjct: 53 DSLKDKVENLERELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLR 112
Query: 269 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTA------------ 412
++ E K ++EK+ QL+ + +++ ++++ E+ + +E S TA
Sbjct: 113 SEKENLTKQIQEKQGQLSELDKLLSSFKSQLEEKEQAEIQIKEESKTAVEMLQNQLKELN 172
Query: 413 --------QQKLLEA-QQSAD----ENNRMCKVLEN---RAQQDEERMDQLTNQLKEARL 544
Q++++A +QS D E +++ +E R + DE++ + QLKE+
Sbjct: 173 EAVAALCGDQEIMKATEQSLDPPIEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESEH 232
Query: 545 LAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEV 712
A+ G+ + + R+L E A ++ ++ L+ +++ + SL+ LE+
Sbjct: 233 HADLLKGRVENLERELEIARTNQEHAALEAENSKGEVETLKAKIEGMTQSLRGLEL 288
Score = 44.0 bits (99), Expect = 6e-04
Identities = 40/222 (18%), Positives = 91/222 (40%), Gaps = 7/222 (3%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
++ A ++ + + ++ EK+N + + Q + + ++ E ++ Q++
Sbjct: 95 EEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSQLEEKEQAEIQIK 154
Query: 248 EDLILNKNKLEQANKDLEEK-------EKQLTATEAEVAALNRKVQQIEEDLEKSEERSG 406
E+ L+ K+L E ++ + ATE + + Q+ +EK R
Sbjct: 155 EESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSLDPPIEEEHQLRNSIEKLRARLE 214
Query: 407 TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSR 586
++K L Q E+ +L+ R + E ++ + A L AE++ G+ + +
Sbjct: 215 ADEKKQLCVLQQLKESEHHADLLKGRVENLERELEIARTNQEHAALEAENSKGEVETLKA 274
Query: 587 KLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEV 712
K+ + L E V + ++ L EL+ + LE+
Sbjct: 275 KIEGMTQSLRGLELDVVTIRSEKEDLTNELQKEQERISELEI 316
Score = 38.7 bits (86), Expect = 0.021
Identities = 41/179 (22%), Positives = 86/179 (48%), Gaps = 16/179 (8%)
Frame = +2
Query: 209 EVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNR-KVQQIE--ED 379
E++ ++KL EE L K +++ EE L AT + L + K+ ++
Sbjct: 627 EIQTYREKLTSKEECLSSQKLEIDLLKSSKEELNNSLKATTQILEELKKTKMDNLKYVNQ 686
Query: 380 LEKSEERSGTAQQKLLEA-QQSADENNRMCKVLEN-RAQQDEER--------MDQLTNQL 529
L+K ER+ + L+++ +Q +E + K L +A Q++++ +D+LT ++
Sbjct: 687 LKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQEKQKTGTVMDTKVDELTTEI 746
Query: 530 KEARLLAEDADGKSDEVSRK---LAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSL 697
KE + E+ ++DE K L ++LE A++ +++ A + + + G+ L
Sbjct: 747 KELKETLEEKTKEADEYLDKYCSLLISHEKLEKAKEMLETQVAHLCSQQSKQDSRGSPL 805
Score = 36.3 bits (80), Expect = 0.11
Identities = 32/168 (19%), Positives = 73/168 (43%)
Frame = +2
Query: 161 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 340
EQ NL E + ++++ LQ K A +++ L + ++ + +LE + + +V
Sbjct: 456 EQNLELRNLTVE-LEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKMSFVEKV 514
Query: 341 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 520
+ K +++ ++ + +++ Q++L + E NR+ L+ ++ + DQL
Sbjct: 515 NKMTAKETELQREMHEMAQKTAELQEEL------SGEKNRLAGELQLLLEEIKSSKDQLK 568
Query: 521 NQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXL 664
E L + D + K V +E+ + R+ + K L
Sbjct: 569 ELTLENSELKKSLDCMHKDQVEKEGKVREEIAEYQLRLHEAEKKHQAL 616
Score = 35.9 bits (79), Expect = 0.15
Identities = 21/98 (21%), Positives = 46/98 (46%)
Frame = +2
Query: 419 KLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAF 598
+L Q+ + R + L R + DE++ + +LKE + K + + R+L
Sbjct: 9 RLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERDGENDSLKDKVENLERELQM 68
Query: 599 VEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEV 712
E+ E+ ++ A++ L+ +++ + SLK E+
Sbjct: 69 SEENQELVILDAENSKAEVETLKTQIEEMARSLKVFEL 106
>BC146779-1|AAI46780.1| 1669|Homo sapiens intersectin 2 protein.
Length = 1669
Score = 53.2 bits (122), Expect = 9e-07
Identities = 51/207 (24%), Positives = 96/207 (46%), Gaps = 8/207 (3%)
Frame = +2
Query: 101 KKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLE 280
+KMQ + +K + D + N+ EK + + E Q++ + E K + E
Sbjct: 347 QKMQEEEPQKKLPVTFEDKRKANYERGNMELEKRRQALMEQQQR--EAERKAQKEKEEWE 404
Query: 281 QANKDLEEKE-KQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENN 457
+ ++L+E+E K+ E + +Q EE+ K ER A+Q+L ++ E
Sbjct: 405 RKQRELQEQEWKKQLELEKRLEKQRELERQREEERRKDIERREAAKQELERQRRLEWERI 464
Query: 458 RMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFV-------EDELE 616
R ++L N+ +++E + +L ++ K L E +GK ++S +L V + ELE
Sbjct: 465 RRQELL-NQKNREQEEIVRLNSKKKNLHLELEALNGKHQQISGRLQDVRLKKQTQKTELE 523
Query: 617 VAEDRVKSGDAKISXLEXELKVVGNSL 697
V + + +I L+ EL+ N L
Sbjct: 524 VLDKQCDLEIMEIKQLQQELQEYQNKL 550
Score = 37.1 bits (82), Expect = 0.065
Identities = 33/153 (21%), Positives = 71/153 (46%), Gaps = 2/153 (1%)
Frame = +2
Query: 71 QKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEE 250
+K +K+++ A++ E + + + D+ Q ++ LR E N + L++ L +++
Sbjct: 586 EKEELCQRLKEQLDALEKETASKLSEMDSFNNQLKE--LR-ETYNTQQLALEQ-LYKIKR 641
Query: 251 DLI--LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL 424
D + + + +LE K E E A + + +++ EE+ +K + T Q+K+
Sbjct: 642 DKLKEIERKRLELMQKKKLEDEAARKAKQGKENLWKENLRKEEEEKQKRLQEEKT-QEKI 700
Query: 425 LEAQQSADENNRMCKVLENRAQQDEERMDQLTN 523
E ++ A+E R K ++ E L N
Sbjct: 701 QEEERKAEEKQRKDKDTLKAEEKKRETASVLVN 733
>BC117209-1|AAI17210.1| 1438|Homo sapiens CLIP1 protein protein.
Length = 1438
Score = 53.2 bits (122), Expect = 9e-07
Identities = 41/216 (18%), Positives = 95/216 (43%), Gaps = 8/216 (3%)
Frame = +2
Query: 86 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 265
++A +K+++ +++EK+ KA + ++ + L+ + E + E+ + +E++L +
Sbjct: 797 LEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQIL 856
Query: 266 KNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSA 445
K K +A+++ ++ + T ++ + + DLEK E + K E +
Sbjct: 857 KEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDERE 916
Query: 446 DENNRMCKVLENR----AQQDEERMDQLTNQLKEARLLAEDADG---KSDEVSRKLAFVE 604
++ + + LEN + + QLT E RL D + K + + +F++
Sbjct: 917 EQLIKAKEKLENDIAEIMKMSGDNPSQLTKMNDELRLKERDVEELQLKLTKANENASFLQ 976
Query: 605 DELEVAEDRVKSGDAKISXL-EXELKVVGNSLKSLE 709
+E + + + + E E K + L LE
Sbjct: 977 KSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLE 1012
Score = 47.2 bits (107), Expect = 6e-05
Identities = 67/239 (28%), Positives = 102/239 (42%), Gaps = 20/239 (8%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVR--------EL 223
QQ+AA +KK KL + K +T Q ++ R E+ E + L
Sbjct: 990 QQEAAKKHEEEKKELERKLS--DLEKKMETSHNQCQELKARYERATSETKTKHEEILQNL 1047
Query: 224 QKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERS 403
QK L E+ L + + ++LEE KQ A +A+ A QI E + K E++
Sbjct: 1048 QKTLLDTEDKLKGAREENSGLLQELEELRKQ--AEKAKAAQTAEDAMQIMEQMTK--EKT 1103
Query: 404 GTAQQKLLEAQQSADENNRMCKVLENRAQQDEE---RMDQLT--NQ-----LKEARLLAE 553
T Q +A N + + EN + EE + LT NQ KE L +
Sbjct: 1104 ETLASLEDTKQTNAKLQNELDTLKENNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQ 1163
Query: 554 DADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKIS--XLEXELKVVGNSLKSLEVSEXK 724
A KS ++S A E+ +++AE+ +S D S LE E V+ N L ++ E K
Sbjct: 1164 AAAQKSQQLS---ALQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKRESK 1219
Score = 39.5 bits (88), Expect = 0.012
Identities = 49/214 (22%), Positives = 90/214 (42%), Gaps = 4/214 (1%)
Frame = +2
Query: 47 FNSTGP*QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQ 226
F ST P + KA + + A L++ + + A + R + + E
Sbjct: 283 FPSTTPAKAKANAVRRVMATTSA-SLKRSPSASSLSSMSSVASSVSSRPSRTGL-LTETS 340
Query: 227 KKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSG 406
+ A+ + L++ + +E+ + AEVA V +IE++L + R G
Sbjct: 341 SRYARKISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALA--RDG 398
Query: 407 TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSR 586
Q +LE + D+ M + D E+++ L NQL+E + ED + +E S
Sbjct: 399 H-DQHVLELEAKMDQLRTMVEAA------DREKVE-LLNQLEEEKRKVEDLQFRVEEESI 450
Query: 587 KLAFVEDELEVAED----RVKSGDAKISXLEXEL 676
+E + +++ED + K A+I LE L
Sbjct: 451 TKGDLEQKSQISEDPENTQTKLEHARIKELEQSL 484
Score = 35.1 bits (77), Expect = 0.26
Identities = 48/186 (25%), Positives = 78/186 (41%), Gaps = 5/186 (2%)
Frame = +2
Query: 188 RAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQ 367
R E +E++ L ++ ++ K+KLE ANK E + ++++ QQ
Sbjct: 580 REETHQKEIKALYTATEKLSKENESLKSKLEHANK---ENSDVIALWKSKLETAIASHQQ 636
Query: 368 IEEDLEKSEERS-GTAQQKLLEAQQSADENNRMCK-VLEN-RAQQDEERMDQLTNQLKEA 538
E+L+ S + GT + E + ++ + +EN + QQD ER KE
Sbjct: 637 AMEELKVSFSKGLGTETAEFAELKTQIEKMRLDYQHEIENLQNQQDSER----AAHAKEM 692
Query: 539 RLLAEDADGKSDEVSRKLAFVEDELEVAEDR--VKSGDAKISXLEXELKVVGNSLKSLEV 712
L E L + +L+ AED+ V+ D E E+KV K LEV
Sbjct: 693 EALRAKLMKVIKEKENSLEAIRSKLDKAEDQHLVEMEDTLNKLQEAEIKV-----KELEV 747
Query: 713 SEXKAN 730
+ K N
Sbjct: 748 LQAKCN 753
>BC091490-1|AAH91490.1| 620|Homo sapiens ODF2L protein protein.
Length = 620
Score = 53.2 bits (122), Expect = 9e-07
Identities = 39/136 (28%), Positives = 72/136 (52%), Gaps = 7/136 (5%)
Frame = +2
Query: 152 DTCEQQARDANL--RAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTA 325
+ C Q + NL + E+++ E +EL+KKLA EE L + +N +EK + TA
Sbjct: 469 ENCLIQLKCENLQQKLEQMDAENKELEKKLANQEECL-------KHSNLKFKEKSAEYTA 521
Query: 326 TEAEV-AALNRKVQQIEEDLEKSEERSGTAQQKLL----EAQQSADENNRMCKVLENRAQ 490
++ AAL Q++ E++EK R Q K+L E ++ +E N++ + ++AQ
Sbjct: 522 LARQLEAALEEGRQKVAEEIEKMSSRESALQIKILDLETELRKKNEEQNQLVCKMNSKAQ 581
Query: 491 QDEERMDQLTNQLKEA 538
E + ++ N L+++
Sbjct: 582 HQEVCLKEVQNSLEKS 597
>BC020921-1|AAH20921.1| 560|Homo sapiens ITSN2 protein protein.
Length = 560
Score = 53.2 bits (122), Expect = 9e-07
Identities = 51/207 (24%), Positives = 96/207 (46%), Gaps = 8/207 (3%)
Frame = +2
Query: 101 KKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLE 280
+KMQ + +K + D + N+ EK + + E Q++ + E K + E
Sbjct: 347 QKMQEEEPQKKLPVTFEDKRKANYERGNMELEKRRQALMEQQQR--EAERKAQKEKEEWE 404
Query: 281 QANKDLEEKE-KQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENN 457
+ ++L+E+E K+ E + +Q EE+ K ER A+Q+L ++ E
Sbjct: 405 RKQRELQEQEWKKQLELEKRLEKQRELERQREEERRKDIERREAAKQELERQRRLEWERI 464
Query: 458 RMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFV-------EDELE 616
R ++L N+ +++E + +L ++ K L E +GK ++S +L V + ELE
Sbjct: 465 RRQELL-NQKNREQEEIVRLNSKKKNLHLELEALNGKHQQISGRLQDVRLKKQTQKTELE 523
Query: 617 VAEDRVKSGDAKISXLEXELKVVGNSL 697
V + + +I L+ EL+ N L
Sbjct: 524 VLDKQCDLEIMEIKQLQQELQEYQNKL 550
>AY480051-1|AAR95684.1| 4547|Homo sapiens plectin 11 protein.
Length = 4547
Score = 53.2 bits (122), Expect = 9e-07
Identities = 46/193 (23%), Positives = 88/193 (45%), Gaps = 2/193 (1%)
Frame = +2
Query: 128 KDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEK 307
+ NA D + EQ +A + + EE R ++ +V++ L + Q LEE
Sbjct: 1952 RSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEV 2011
Query: 308 EKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKV--LEN 481
E+ +A+V R ++ E++ + + + A QK L+A++ A K L+
Sbjct: 2012 ER----LKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQ 2067
Query: 482 RAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISX 661
QQ++ +DQL + + AR AE+A+ + R+ A ++E AE R+K + +
Sbjct: 2068 TLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAE-RLKQSAEEQAQ 2126
Query: 662 LEXELKVVGNSLK 700
+ + L+
Sbjct: 2127 ARAQAQAAAEKLR 2139
Score = 42.7 bits (96), Expect = 0.001
Identities = 43/184 (23%), Positives = 84/184 (45%), Gaps = 9/184 (4%)
Frame = +2
Query: 95 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQ-----VEEDLI 259
+++ +Q + ++A+ QQ +A E+ E+ Q K + ++ + +
Sbjct: 1592 LERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEV 1651
Query: 260 LNKNKLEQANKDLEEKEKQLTAT---EAEVAALNRKVQQIEEDLEKSEERS-GTAQQKLL 427
+ L QA + +++E + A +AE A+ ++ + E++LEK + + GTAQQ+L
Sbjct: 1652 AQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQR-ELAEQELEKQRQLAEGTAQQRLA 1710
Query: 428 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 607
Q+ L +Q E++ L +L + A A K E+ +LA V
Sbjct: 1711 AEQELIR--------LRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRA 1762
Query: 608 ELEV 619
E+EV
Sbjct: 1763 EMEV 1766
Score = 37.5 bits (83), Expect = 0.049
Identities = 46/214 (21%), Positives = 91/214 (42%), Gaps = 12/214 (5%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
Q A M+ KK + +K + T Q + + + ++EE++ L+ + +
Sbjct: 2161 QAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAA 2220
Query: 248 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAAL-----NRKVQQIEEDLEKSEE----- 397
+ +L +EE K EAE AL + + ++E+ EK ++
Sbjct: 2221 RQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEA 2280
Query: 398 -RSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLK-EARLLAEDADGKS 571
R A Q+ +Q A+E+ + L + +++ + Q +LK EA LL + + +
Sbjct: 2281 ARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKE-LA 2339
Query: 572 DEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXE 673
E +R+L ED+ ++A+ + LE E
Sbjct: 2340 QEQARRLQ--EDKEQMAQQLAEETQGFQRTLEAE 2371
Score = 37.5 bits (83), Expect = 0.049
Identities = 33/147 (22%), Positives = 71/147 (48%), Gaps = 5/147 (3%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQ---ARDANLRAEKVNEEVRELQKKLA 238
QQ+A + ++MQ ++ E+ + + +Q +D+ L+ E+ E+ + KL
Sbjct: 2463 QQEAKLLQLKSEEMQTVQQEQ--LLQETQALQQSFLSEKDSLLQRERFIEQEKA---KLE 2517
Query: 239 QVEEDLILNKNKL-EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLE-KSEERSGTA 412
Q+ +D + +L E+ + ++ E++ A + R+ + EE + K EE
Sbjct: 2518 QLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLE 2577
Query: 413 QQKLLEAQQSADENNRMCKVLENRAQQ 493
QQ+ + + A+EN R+ + L+ +Q
Sbjct: 2578 QQRRQQEELLAEENQRLREQLQLLEEQ 2604
Score = 37.1 bits (82), Expect = 0.065
Identities = 30/131 (22%), Positives = 63/131 (48%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
+ +A + +K ++ E+ +KA EQ +D +A+++ EE + Q+++ Q
Sbjct: 2487 ETQALQQSFLSEKDSLLQRERFIEQEKAKL-EQLFQDEVAKAQQLREEQQRQQQQMEQER 2545
Query: 248 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 427
+ L+ + +E+A + E E+ + + E+ QQ+E+ + EE Q+L
Sbjct: 2546 QRLVAS---MEEARRRQHEAEEGVRRKQEEL-------QQLEQQRRQQEELLAEENQRLR 2595
Query: 428 EAQQSADENNR 460
E Q +E +R
Sbjct: 2596 EQLQLLEEQHR 2606
Score = 31.1 bits (67), Expect = 4.3
Identities = 27/140 (19%), Positives = 60/140 (42%), Gaps = 2/140 (1%)
Frame = +2
Query: 125 EKDNAMDKADTCEQQARDAN-LRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLE 301
++ A+++ + + + +A LR E R+LQ ++ L + A + E
Sbjct: 2003 QRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKE 2062
Query: 302 EKEKQLTATEAEVA-ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLE 478
++ +Q E V L + + E++EE A+++ ++++ +E R+ + E
Sbjct: 2063 QELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAE 2122
Query: 479 NRAQQDEERMDQLTNQLKEA 538
+AQ + KEA
Sbjct: 2123 EQAQARAQAQAAAEKLRKEA 2142
>AY480050-1|AAR95683.1| 4551|Homo sapiens plectin 10 protein.
Length = 4551
Score = 53.2 bits (122), Expect = 9e-07
Identities = 46/193 (23%), Positives = 88/193 (45%), Gaps = 2/193 (1%)
Frame = +2
Query: 128 KDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEK 307
+ NA D + EQ +A + + EE R ++ +V++ L + Q LEE
Sbjct: 1956 RSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEV 2015
Query: 308 EKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKV--LEN 481
E+ +A+V R ++ E++ + + + A QK L+A++ A K L+
Sbjct: 2016 ER----LKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQ 2071
Query: 482 RAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISX 661
QQ++ +DQL + + AR AE+A+ + R+ A ++E AE R+K + +
Sbjct: 2072 TLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAE-RLKQSAEEQAQ 2130
Query: 662 LEXELKVVGNSLK 700
+ + L+
Sbjct: 2131 ARAQAQAAAEKLR 2143
Score = 42.7 bits (96), Expect = 0.001
Identities = 43/184 (23%), Positives = 84/184 (45%), Gaps = 9/184 (4%)
Frame = +2
Query: 95 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQ-----VEEDLI 259
+++ +Q + ++A+ QQ +A E+ E+ Q K + ++ + +
Sbjct: 1596 LERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEV 1655
Query: 260 LNKNKLEQANKDLEEKEKQLTAT---EAEVAALNRKVQQIEEDLEKSEERS-GTAQQKLL 427
+ L QA + +++E + A +AE A+ ++ + E++LEK + + GTAQQ+L
Sbjct: 1656 AQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQR-ELAEQELEKQRQLAEGTAQQRLA 1714
Query: 428 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 607
Q+ L +Q E++ L +L + A A K E+ +LA V
Sbjct: 1715 AEQELIR--------LRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRA 1766
Query: 608 ELEV 619
E+EV
Sbjct: 1767 EMEV 1770
Score = 37.5 bits (83), Expect = 0.049
Identities = 46/214 (21%), Positives = 91/214 (42%), Gaps = 12/214 (5%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
Q A M+ KK + +K + T Q + + + ++EE++ L+ + +
Sbjct: 2165 QAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAA 2224
Query: 248 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAAL-----NRKVQQIEEDLEKSEE----- 397
+ +L +EE K EAE AL + + ++E+ EK ++
Sbjct: 2225 RQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEA 2284
Query: 398 -RSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLK-EARLLAEDADGKS 571
R A Q+ +Q A+E+ + L + +++ + Q +LK EA LL + + +
Sbjct: 2285 ARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKE-LA 2343
Query: 572 DEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXE 673
E +R+L ED+ ++A+ + LE E
Sbjct: 2344 QEQARRLQ--EDKEQMAQQLAEETQGFQRTLEAE 2375
Score = 37.5 bits (83), Expect = 0.049
Identities = 33/147 (22%), Positives = 71/147 (48%), Gaps = 5/147 (3%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQ---ARDANLRAEKVNEEVRELQKKLA 238
QQ+A + ++MQ ++ E+ + + +Q +D+ L+ E+ E+ + KL
Sbjct: 2467 QQEAKLLQLKSEEMQTVQQEQ--LLQETQALQQSFLSEKDSLLQRERFIEQEKA---KLE 2521
Query: 239 QVEEDLILNKNKL-EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLE-KSEERSGTA 412
Q+ +D + +L E+ + ++ E++ A + R+ + EE + K EE
Sbjct: 2522 QLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLE 2581
Query: 413 QQKLLEAQQSADENNRMCKVLENRAQQ 493
QQ+ + + A+EN R+ + L+ +Q
Sbjct: 2582 QQRRQQEELLAEENQRLREQLQLLEEQ 2608
Score = 37.1 bits (82), Expect = 0.065
Identities = 30/131 (22%), Positives = 63/131 (48%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
+ +A + +K ++ E+ +KA EQ +D +A+++ EE + Q+++ Q
Sbjct: 2491 ETQALQQSFLSEKDSLLQRERFIEQEKAKL-EQLFQDEVAKAQQLREEQQRQQQQMEQER 2549
Query: 248 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 427
+ L+ + +E+A + E E+ + + E+ QQ+E+ + EE Q+L
Sbjct: 2550 QRLVAS---MEEARRRQHEAEEGVRRKQEEL-------QQLEQQRRQQEELLAEENQRLR 2599
Query: 428 EAQQSADENNR 460
E Q +E +R
Sbjct: 2600 EQLQLLEEQHR 2610
Score = 31.1 bits (67), Expect = 4.3
Identities = 27/140 (19%), Positives = 60/140 (42%), Gaps = 2/140 (1%)
Frame = +2
Query: 125 EKDNAMDKADTCEQQARDAN-LRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLE 301
++ A+++ + + + +A LR E R+LQ ++ L + A + E
Sbjct: 2007 QRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKE 2066
Query: 302 EKEKQLTATEAEVA-ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLE 478
++ +Q E V L + + E++EE A+++ ++++ +E R+ + E
Sbjct: 2067 QELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAE 2126
Query: 479 NRAQQDEERMDQLTNQLKEA 538
+AQ + KEA
Sbjct: 2127 EQAQARAQAQAAAEKLRKEA 2146
>AY480049-1|AAR95682.1| 4547|Homo sapiens plectin 8 protein.
Length = 4547
Score = 53.2 bits (122), Expect = 9e-07
Identities = 46/193 (23%), Positives = 88/193 (45%), Gaps = 2/193 (1%)
Frame = +2
Query: 128 KDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEK 307
+ NA D + EQ +A + + EE R ++ +V++ L + Q LEE
Sbjct: 1952 RSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEV 2011
Query: 308 EKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKV--LEN 481
E+ +A+V R ++ E++ + + + A QK L+A++ A K L+
Sbjct: 2012 ER----LKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQ 2067
Query: 482 RAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISX 661
QQ++ +DQL + + AR AE+A+ + R+ A ++E AE R+K + +
Sbjct: 2068 TLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAE-RLKQSAEEQAQ 2126
Query: 662 LEXELKVVGNSLK 700
+ + L+
Sbjct: 2127 ARAQAQAAAEKLR 2139
Score = 42.7 bits (96), Expect = 0.001
Identities = 43/184 (23%), Positives = 84/184 (45%), Gaps = 9/184 (4%)
Frame = +2
Query: 95 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQ-----VEEDLI 259
+++ +Q + ++A+ QQ +A E+ E+ Q K + ++ + +
Sbjct: 1592 LERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEV 1651
Query: 260 LNKNKLEQANKDLEEKEKQLTAT---EAEVAALNRKVQQIEEDLEKSEERS-GTAQQKLL 427
+ L QA + +++E + A +AE A+ ++ + E++LEK + + GTAQQ+L
Sbjct: 1652 AQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQR-ELAEQELEKQRQLAEGTAQQRLA 1710
Query: 428 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 607
Q+ L +Q E++ L +L + A A K E+ +LA V
Sbjct: 1711 AEQELIR--------LRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRA 1762
Query: 608 ELEV 619
E+EV
Sbjct: 1763 EMEV 1766
Score = 37.5 bits (83), Expect = 0.049
Identities = 46/214 (21%), Positives = 91/214 (42%), Gaps = 12/214 (5%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
Q A M+ KK + +K + T Q + + + ++EE++ L+ + +
Sbjct: 2161 QAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAA 2220
Query: 248 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAAL-----NRKVQQIEEDLEKSEE----- 397
+ +L +EE K EAE AL + + ++E+ EK ++
Sbjct: 2221 RQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEA 2280
Query: 398 -RSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLK-EARLLAEDADGKS 571
R A Q+ +Q A+E+ + L + +++ + Q +LK EA LL + + +
Sbjct: 2281 ARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKE-LA 2339
Query: 572 DEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXE 673
E +R+L ED+ ++A+ + LE E
Sbjct: 2340 QEQARRLQ--EDKEQMAQQLAEETQGFQRTLEAE 2371
Score = 37.5 bits (83), Expect = 0.049
Identities = 33/147 (22%), Positives = 71/147 (48%), Gaps = 5/147 (3%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQ---ARDANLRAEKVNEEVRELQKKLA 238
QQ+A + ++MQ ++ E+ + + +Q +D+ L+ E+ E+ + KL
Sbjct: 2463 QQEAKLLQLKSEEMQTVQQEQ--LLQETQALQQSFLSEKDSLLQRERFIEQEKA---KLE 2517
Query: 239 QVEEDLILNKNKL-EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLE-KSEERSGTA 412
Q+ +D + +L E+ + ++ E++ A + R+ + EE + K EE
Sbjct: 2518 QLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLE 2577
Query: 413 QQKLLEAQQSADENNRMCKVLENRAQQ 493
QQ+ + + A+EN R+ + L+ +Q
Sbjct: 2578 QQRRQQEELLAEENQRLREQLQLLEEQ 2604
Score = 37.1 bits (82), Expect = 0.065
Identities = 30/131 (22%), Positives = 63/131 (48%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
+ +A + +K ++ E+ +KA EQ +D +A+++ EE + Q+++ Q
Sbjct: 2487 ETQALQQSFLSEKDSLLQRERFIEQEKAKL-EQLFQDEVAKAQQLREEQQRQQQQMEQER 2545
Query: 248 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 427
+ L+ + +E+A + E E+ + + E+ QQ+E+ + EE Q+L
Sbjct: 2546 QRLVAS---MEEARRRQHEAEEGVRRKQEEL-------QQLEQQRRQQEELLAEENQRLR 2595
Query: 428 EAQQSADENNR 460
E Q +E +R
Sbjct: 2596 EQLQLLEEQHR 2606
Score = 31.1 bits (67), Expect = 4.3
Identities = 27/140 (19%), Positives = 60/140 (42%), Gaps = 2/140 (1%)
Frame = +2
Query: 125 EKDNAMDKADTCEQQARDAN-LRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLE 301
++ A+++ + + + +A LR E R+LQ ++ L + A + E
Sbjct: 2003 QRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKE 2062
Query: 302 EKEKQLTATEAEVA-ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLE 478
++ +Q E V L + + E++EE A+++ ++++ +E R+ + E
Sbjct: 2063 QELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAE 2122
Query: 479 NRAQQDEERMDQLTNQLKEA 538
+AQ + KEA
Sbjct: 2123 EQAQARAQAQAAAEKLRKEA 2142
>AY480048-1|AAR95681.1| 4515|Homo sapiens plectin 7 protein.
Length = 4515
Score = 53.2 bits (122), Expect = 9e-07
Identities = 46/193 (23%), Positives = 88/193 (45%), Gaps = 2/193 (1%)
Frame = +2
Query: 128 KDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEK 307
+ NA D + EQ +A + + EE R ++ +V++ L + Q LEE
Sbjct: 1920 RSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEV 1979
Query: 308 EKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKV--LEN 481
E+ +A+V R ++ E++ + + + A QK L+A++ A K L+
Sbjct: 1980 ER----LKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQ 2035
Query: 482 RAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISX 661
QQ++ +DQL + + AR AE+A+ + R+ A ++E AE R+K + +
Sbjct: 2036 TLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAE-RLKQSAEEQAQ 2094
Query: 662 LEXELKVVGNSLK 700
+ + L+
Sbjct: 2095 ARAQAQAAAEKLR 2107
Score = 42.7 bits (96), Expect = 0.001
Identities = 43/184 (23%), Positives = 84/184 (45%), Gaps = 9/184 (4%)
Frame = +2
Query: 95 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQ-----VEEDLI 259
+++ +Q + ++A+ QQ +A E+ E+ Q K + ++ + +
Sbjct: 1560 LERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEV 1619
Query: 260 LNKNKLEQANKDLEEKEKQLTAT---EAEVAALNRKVQQIEEDLEKSEERS-GTAQQKLL 427
+ L QA + +++E + A +AE A+ ++ + E++LEK + + GTAQQ+L
Sbjct: 1620 AQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQR-ELAEQELEKQRQLAEGTAQQRLA 1678
Query: 428 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 607
Q+ L +Q E++ L +L + A A K E+ +LA V
Sbjct: 1679 AEQELIR--------LRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRA 1730
Query: 608 ELEV 619
E+EV
Sbjct: 1731 EMEV 1734
Score = 37.5 bits (83), Expect = 0.049
Identities = 46/214 (21%), Positives = 91/214 (42%), Gaps = 12/214 (5%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
Q A M+ KK + +K + T Q + + + ++EE++ L+ + +
Sbjct: 2129 QAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAA 2188
Query: 248 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAAL-----NRKVQQIEEDLEKSEE----- 397
+ +L +EE K EAE AL + + ++E+ EK ++
Sbjct: 2189 RQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEA 2248
Query: 398 -RSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLK-EARLLAEDADGKS 571
R A Q+ +Q A+E+ + L + +++ + Q +LK EA LL + + +
Sbjct: 2249 ARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKE-LA 2307
Query: 572 DEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXE 673
E +R+L ED+ ++A+ + LE E
Sbjct: 2308 QEQARRLQ--EDKEQMAQQLAEETQGFQRTLEAE 2339
Score = 37.5 bits (83), Expect = 0.049
Identities = 33/147 (22%), Positives = 71/147 (48%), Gaps = 5/147 (3%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQ---ARDANLRAEKVNEEVRELQKKLA 238
QQ+A + ++MQ ++ E+ + + +Q +D+ L+ E+ E+ + KL
Sbjct: 2431 QQEAKLLQLKSEEMQTVQQEQ--LLQETQALQQSFLSEKDSLLQRERFIEQEKA---KLE 2485
Query: 239 QVEEDLILNKNKL-EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLE-KSEERSGTA 412
Q+ +D + +L E+ + ++ E++ A + R+ + EE + K EE
Sbjct: 2486 QLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLE 2545
Query: 413 QQKLLEAQQSADENNRMCKVLENRAQQ 493
QQ+ + + A+EN R+ + L+ +Q
Sbjct: 2546 QQRRQQEELLAEENQRLREQLQLLEEQ 2572
Score = 37.1 bits (82), Expect = 0.065
Identities = 30/131 (22%), Positives = 63/131 (48%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
+ +A + +K ++ E+ +KA EQ +D +A+++ EE + Q+++ Q
Sbjct: 2455 ETQALQQSFLSEKDSLLQRERFIEQEKAKL-EQLFQDEVAKAQQLREEQQRQQQQMEQER 2513
Query: 248 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 427
+ L+ + +E+A + E E+ + + E+ QQ+E+ + EE Q+L
Sbjct: 2514 QRLVAS---MEEARRRQHEAEEGVRRKQEEL-------QQLEQQRRQQEELLAEENQRLR 2563
Query: 428 EAQQSADENNR 460
E Q +E +R
Sbjct: 2564 EQLQLLEEQHR 2574
Score = 31.1 bits (67), Expect = 4.3
Identities = 27/140 (19%), Positives = 60/140 (42%), Gaps = 2/140 (1%)
Frame = +2
Query: 125 EKDNAMDKADTCEQQARDAN-LRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLE 301
++ A+++ + + + +A LR E R+LQ ++ L + A + E
Sbjct: 1971 QRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKE 2030
Query: 302 EKEKQLTATEAEVA-ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLE 478
++ +Q E V L + + E++EE A+++ ++++ +E R+ + E
Sbjct: 2031 QELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAE 2090
Query: 479 NRAQQDEERMDQLTNQLKEA 538
+AQ + KEA
Sbjct: 2091 EQAQARAQAQAAAEKLRKEA 2110
>AY480047-1|AAR95680.1| 4684|Homo sapiens plectin 6 protein.
Length = 4684
Score = 53.2 bits (122), Expect = 9e-07
Identities = 46/193 (23%), Positives = 88/193 (45%), Gaps = 2/193 (1%)
Frame = +2
Query: 128 KDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEK 307
+ NA D + EQ +A + + EE R ++ +V++ L + Q LEE
Sbjct: 2089 RSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEV 2148
Query: 308 EKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKV--LEN 481
E+ +A+V R ++ E++ + + + A QK L+A++ A K L+
Sbjct: 2149 ER----LKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQ 2204
Query: 482 RAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISX 661
QQ++ +DQL + + AR AE+A+ + R+ A ++E AE R+K + +
Sbjct: 2205 TLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAE-RLKQSAEEQAQ 2263
Query: 662 LEXELKVVGNSLK 700
+ + L+
Sbjct: 2264 ARAQAQAAAEKLR 2276
Score = 42.7 bits (96), Expect = 0.001
Identities = 43/184 (23%), Positives = 84/184 (45%), Gaps = 9/184 (4%)
Frame = +2
Query: 95 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQ-----VEEDLI 259
+++ +Q + ++A+ QQ +A E+ E+ Q K + ++ + +
Sbjct: 1729 LERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEV 1788
Query: 260 LNKNKLEQANKDLEEKEKQLTAT---EAEVAALNRKVQQIEEDLEKSEERS-GTAQQKLL 427
+ L QA + +++E + A +AE A+ ++ + E++LEK + + GTAQQ+L
Sbjct: 1789 AQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQR-ELAEQELEKQRQLAEGTAQQRLA 1847
Query: 428 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 607
Q+ L +Q E++ L +L + A A K E+ +LA V
Sbjct: 1848 AEQELIR--------LRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRA 1899
Query: 608 ELEV 619
E+EV
Sbjct: 1900 EMEV 1903
Score = 37.5 bits (83), Expect = 0.049
Identities = 46/214 (21%), Positives = 91/214 (42%), Gaps = 12/214 (5%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
Q A M+ KK + +K + T Q + + + ++EE++ L+ + +
Sbjct: 2298 QAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAA 2357
Query: 248 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAAL-----NRKVQQIEEDLEKSEE----- 397
+ +L +EE K EAE AL + + ++E+ EK ++
Sbjct: 2358 RQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEA 2417
Query: 398 -RSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLK-EARLLAEDADGKS 571
R A Q+ +Q A+E+ + L + +++ + Q +LK EA LL + + +
Sbjct: 2418 ARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKE-LA 2476
Query: 572 DEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXE 673
E +R+L ED+ ++A+ + LE E
Sbjct: 2477 QEQARRLQ--EDKEQMAQQLAEETQGFQRTLEAE 2508
Score = 37.5 bits (83), Expect = 0.049
Identities = 33/147 (22%), Positives = 71/147 (48%), Gaps = 5/147 (3%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQ---ARDANLRAEKVNEEVRELQKKLA 238
QQ+A + ++MQ ++ E+ + + +Q +D+ L+ E+ E+ + KL
Sbjct: 2600 QQEAKLLQLKSEEMQTVQQEQ--LLQETQALQQSFLSEKDSLLQRERFIEQEKA---KLE 2654
Query: 239 QVEEDLILNKNKL-EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLE-KSEERSGTA 412
Q+ +D + +L E+ + ++ E++ A + R+ + EE + K EE
Sbjct: 2655 QLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLE 2714
Query: 413 QQKLLEAQQSADENNRMCKVLENRAQQ 493
QQ+ + + A+EN R+ + L+ +Q
Sbjct: 2715 QQRRQQEELLAEENQRLREQLQLLEEQ 2741
Score = 37.1 bits (82), Expect = 0.065
Identities = 30/131 (22%), Positives = 63/131 (48%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
+ +A + +K ++ E+ +KA EQ +D +A+++ EE + Q+++ Q
Sbjct: 2624 ETQALQQSFLSEKDSLLQRERFIEQEKAKL-EQLFQDEVAKAQQLREEQQRQQQQMEQER 2682
Query: 248 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 427
+ L+ + +E+A + E E+ + + E+ QQ+E+ + EE Q+L
Sbjct: 2683 QRLVAS---MEEARRRQHEAEEGVRRKQEEL-------QQLEQQRRQQEELLAEENQRLR 2732
Query: 428 EAQQSADENNR 460
E Q +E +R
Sbjct: 2733 EQLQLLEEQHR 2743
Score = 31.1 bits (67), Expect = 4.3
Identities = 27/140 (19%), Positives = 60/140 (42%), Gaps = 2/140 (1%)
Frame = +2
Query: 125 EKDNAMDKADTCEQQARDAN-LRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLE 301
++ A+++ + + + +A LR E R+LQ ++ L + A + E
Sbjct: 2140 QRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKE 2199
Query: 302 EKEKQLTATEAEVA-ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLE 478
++ +Q E V L + + E++EE A+++ ++++ +E R+ + E
Sbjct: 2200 QELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAE 2259
Query: 479 NRAQQDEERMDQLTNQLKEA 538
+AQ + KEA
Sbjct: 2260 EQAQARAQAQAAAEKLRKEA 2279
>AY480046-1|AAR95679.1| 4525|Homo sapiens plectin 3 protein.
Length = 4525
Score = 53.2 bits (122), Expect = 9e-07
Identities = 46/193 (23%), Positives = 88/193 (45%), Gaps = 2/193 (1%)
Frame = +2
Query: 128 KDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEK 307
+ NA D + EQ +A + + EE R ++ +V++ L + Q LEE
Sbjct: 1930 RSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEV 1989
Query: 308 EKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKV--LEN 481
E+ +A+V R ++ E++ + + + A QK L+A++ A K L+
Sbjct: 1990 ER----LKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQ 2045
Query: 482 RAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISX 661
QQ++ +DQL + + AR AE+A+ + R+ A ++E AE R+K + +
Sbjct: 2046 TLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAE-RLKQSAEEQAQ 2104
Query: 662 LEXELKVVGNSLK 700
+ + L+
Sbjct: 2105 ARAQAQAAAEKLR 2117
Score = 42.7 bits (96), Expect = 0.001
Identities = 43/184 (23%), Positives = 84/184 (45%), Gaps = 9/184 (4%)
Frame = +2
Query: 95 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQ-----VEEDLI 259
+++ +Q + ++A+ QQ +A E+ E+ Q K + ++ + +
Sbjct: 1570 LERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEV 1629
Query: 260 LNKNKLEQANKDLEEKEKQLTAT---EAEVAALNRKVQQIEEDLEKSEERS-GTAQQKLL 427
+ L QA + +++E + A +AE A+ ++ + E++LEK + + GTAQQ+L
Sbjct: 1630 AQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQR-ELAEQELEKQRQLAEGTAQQRLA 1688
Query: 428 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 607
Q+ L +Q E++ L +L + A A K E+ +LA V
Sbjct: 1689 AEQELIR--------LRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRA 1740
Query: 608 ELEV 619
E+EV
Sbjct: 1741 EMEV 1744
Score = 37.5 bits (83), Expect = 0.049
Identities = 46/214 (21%), Positives = 91/214 (42%), Gaps = 12/214 (5%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
Q A M+ KK + +K + T Q + + + ++EE++ L+ + +
Sbjct: 2139 QAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAA 2198
Query: 248 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAAL-----NRKVQQIEEDLEKSEE----- 397
+ +L +EE K EAE AL + + ++E+ EK ++
Sbjct: 2199 RQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEA 2258
Query: 398 -RSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLK-EARLLAEDADGKS 571
R A Q+ +Q A+E+ + L + +++ + Q +LK EA LL + + +
Sbjct: 2259 ARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKE-LA 2317
Query: 572 DEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXE 673
E +R+L ED+ ++A+ + LE E
Sbjct: 2318 QEQARRLQ--EDKEQMAQQLAEETQGFQRTLEAE 2349
Score = 37.5 bits (83), Expect = 0.049
Identities = 33/147 (22%), Positives = 71/147 (48%), Gaps = 5/147 (3%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQ---ARDANLRAEKVNEEVRELQKKLA 238
QQ+A + ++MQ ++ E+ + + +Q +D+ L+ E+ E+ + KL
Sbjct: 2441 QQEAKLLQLKSEEMQTVQQEQ--LLQETQALQQSFLSEKDSLLQRERFIEQEKA---KLE 2495
Query: 239 QVEEDLILNKNKL-EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLE-KSEERSGTA 412
Q+ +D + +L E+ + ++ E++ A + R+ + EE + K EE
Sbjct: 2496 QLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLE 2555
Query: 413 QQKLLEAQQSADENNRMCKVLENRAQQ 493
QQ+ + + A+EN R+ + L+ +Q
Sbjct: 2556 QQRRQQEELLAEENQRLREQLQLLEEQ 2582
Score = 37.1 bits (82), Expect = 0.065
Identities = 30/131 (22%), Positives = 63/131 (48%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
+ +A + +K ++ E+ +KA EQ +D +A+++ EE + Q+++ Q
Sbjct: 2465 ETQALQQSFLSEKDSLLQRERFIEQEKAKL-EQLFQDEVAKAQQLREEQQRQQQQMEQER 2523
Query: 248 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 427
+ L+ + +E+A + E E+ + + E+ QQ+E+ + EE Q+L
Sbjct: 2524 QRLVAS---MEEARRRQHEAEEGVRRKQEEL-------QQLEQQRRQQEELLAEENQRLR 2573
Query: 428 EAQQSADENNR 460
E Q +E +R
Sbjct: 2574 EQLQLLEEQHR 2584
Score = 31.1 bits (67), Expect = 4.3
Identities = 27/140 (19%), Positives = 60/140 (42%), Gaps = 2/140 (1%)
Frame = +2
Query: 125 EKDNAMDKADTCEQQARDAN-LRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLE 301
++ A+++ + + + +A LR E R+LQ ++ L + A + E
Sbjct: 1981 QRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKE 2040
Query: 302 EKEKQLTATEAEVA-ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLE 478
++ +Q E V L + + E++EE A+++ ++++ +E R+ + E
Sbjct: 2041 QELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAE 2100
Query: 479 NRAQQDEERMDQLTNQLKEA 538
+AQ + KEA
Sbjct: 2101 EQAQARAQAQAAAEKLRKEA 2120
>AY480045-1|AAR95678.1| 4533|Homo sapiens plectin 2 protein.
Length = 4533
Score = 53.2 bits (122), Expect = 9e-07
Identities = 46/193 (23%), Positives = 88/193 (45%), Gaps = 2/193 (1%)
Frame = +2
Query: 128 KDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEK 307
+ NA D + EQ +A + + EE R ++ +V++ L + Q LEE
Sbjct: 1938 RSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEV 1997
Query: 308 EKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKV--LEN 481
E+ +A+V R ++ E++ + + + A QK L+A++ A K L+
Sbjct: 1998 ER----LKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQ 2053
Query: 482 RAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISX 661
QQ++ +DQL + + AR AE+A+ + R+ A ++E AE R+K + +
Sbjct: 2054 TLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAE-RLKQSAEEQAQ 2112
Query: 662 LEXELKVVGNSLK 700
+ + L+
Sbjct: 2113 ARAQAQAAAEKLR 2125
Score = 42.7 bits (96), Expect = 0.001
Identities = 43/184 (23%), Positives = 84/184 (45%), Gaps = 9/184 (4%)
Frame = +2
Query: 95 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQ-----VEEDLI 259
+++ +Q + ++A+ QQ +A E+ E+ Q K + ++ + +
Sbjct: 1578 LERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEV 1637
Query: 260 LNKNKLEQANKDLEEKEKQLTAT---EAEVAALNRKVQQIEEDLEKSEERS-GTAQQKLL 427
+ L QA + +++E + A +AE A+ ++ + E++LEK + + GTAQQ+L
Sbjct: 1638 AQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQR-ELAEQELEKQRQLAEGTAQQRLA 1696
Query: 428 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 607
Q+ L +Q E++ L +L + A A K E+ +LA V
Sbjct: 1697 AEQELIR--------LRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRA 1748
Query: 608 ELEV 619
E+EV
Sbjct: 1749 EMEV 1752
Score = 37.5 bits (83), Expect = 0.049
Identities = 46/214 (21%), Positives = 91/214 (42%), Gaps = 12/214 (5%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
Q A M+ KK + +K + T Q + + + ++EE++ L+ + +
Sbjct: 2147 QAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAA 2206
Query: 248 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAAL-----NRKVQQIEEDLEKSEE----- 397
+ +L +EE K EAE AL + + ++E+ EK ++
Sbjct: 2207 RQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEA 2266
Query: 398 -RSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLK-EARLLAEDADGKS 571
R A Q+ +Q A+E+ + L + +++ + Q +LK EA LL + + +
Sbjct: 2267 ARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKE-LA 2325
Query: 572 DEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXE 673
E +R+L ED+ ++A+ + LE E
Sbjct: 2326 QEQARRLQ--EDKEQMAQQLAEETQGFQRTLEAE 2357
Score = 37.5 bits (83), Expect = 0.049
Identities = 33/147 (22%), Positives = 71/147 (48%), Gaps = 5/147 (3%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQ---ARDANLRAEKVNEEVRELQKKLA 238
QQ+A + ++MQ ++ E+ + + +Q +D+ L+ E+ E+ + KL
Sbjct: 2449 QQEAKLLQLKSEEMQTVQQEQ--LLQETQALQQSFLSEKDSLLQRERFIEQEKA---KLE 2503
Query: 239 QVEEDLILNKNKL-EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLE-KSEERSGTA 412
Q+ +D + +L E+ + ++ E++ A + R+ + EE + K EE
Sbjct: 2504 QLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLE 2563
Query: 413 QQKLLEAQQSADENNRMCKVLENRAQQ 493
QQ+ + + A+EN R+ + L+ +Q
Sbjct: 2564 QQRRQQEELLAEENQRLREQLQLLEEQ 2590
Score = 37.1 bits (82), Expect = 0.065
Identities = 30/131 (22%), Positives = 63/131 (48%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
+ +A + +K ++ E+ +KA EQ +D +A+++ EE + Q+++ Q
Sbjct: 2473 ETQALQQSFLSEKDSLLQRERFIEQEKAKL-EQLFQDEVAKAQQLREEQQRQQQQMEQER 2531
Query: 248 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 427
+ L+ + +E+A + E E+ + + E+ QQ+E+ + EE Q+L
Sbjct: 2532 QRLVAS---MEEARRRQHEAEEGVRRKQEEL-------QQLEQQRRQQEELLAEENQRLR 2581
Query: 428 EAQQSADENNR 460
E Q +E +R
Sbjct: 2582 EQLQLLEEQHR 2592
Score = 31.1 bits (67), Expect = 4.3
Identities = 27/140 (19%), Positives = 60/140 (42%), Gaps = 2/140 (1%)
Frame = +2
Query: 125 EKDNAMDKADTCEQQARDAN-LRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLE 301
++ A+++ + + + +A LR E R+LQ ++ L + A + E
Sbjct: 1989 QRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKE 2048
Query: 302 EKEKQLTATEAEVA-ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLE 478
++ +Q E V L + + E++EE A+++ ++++ +E R+ + E
Sbjct: 2049 QELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAE 2108
Query: 479 NRAQQDEERMDQLTNQLKEA 538
+AQ + KEA
Sbjct: 2109 EQAQARAQAQAAAEKLRKEA 2128
>AY480044-1|AAR95677.1| 4574|Homo sapiens plectin 1 protein.
Length = 4574
Score = 53.2 bits (122), Expect = 9e-07
Identities = 46/193 (23%), Positives = 88/193 (45%), Gaps = 2/193 (1%)
Frame = +2
Query: 128 KDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEK 307
+ NA D + EQ +A + + EE R ++ +V++ L + Q LEE
Sbjct: 1979 RSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEV 2038
Query: 308 EKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKV--LEN 481
E+ +A+V R ++ E++ + + + A QK L+A++ A K L+
Sbjct: 2039 ER----LKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQ 2094
Query: 482 RAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISX 661
QQ++ +DQL + + AR AE+A+ + R+ A ++E AE R+K + +
Sbjct: 2095 TLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAE-RLKQSAEEQAQ 2153
Query: 662 LEXELKVVGNSLK 700
+ + L+
Sbjct: 2154 ARAQAQAAAEKLR 2166
Score = 42.7 bits (96), Expect = 0.001
Identities = 43/184 (23%), Positives = 84/184 (45%), Gaps = 9/184 (4%)
Frame = +2
Query: 95 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQ-----VEEDLI 259
+++ +Q + ++A+ QQ +A E+ E+ Q K + ++ + +
Sbjct: 1619 LERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEV 1678
Query: 260 LNKNKLEQANKDLEEKEKQLTAT---EAEVAALNRKVQQIEEDLEKSEERS-GTAQQKLL 427
+ L QA + +++E + A +AE A+ ++ + E++LEK + + GTAQQ+L
Sbjct: 1679 AQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQR-ELAEQELEKQRQLAEGTAQQRLA 1737
Query: 428 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 607
Q+ L +Q E++ L +L + A A K E+ +LA V
Sbjct: 1738 AEQELIR--------LRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRA 1789
Query: 608 ELEV 619
E+EV
Sbjct: 1790 EMEV 1793
Score = 37.5 bits (83), Expect = 0.049
Identities = 46/214 (21%), Positives = 91/214 (42%), Gaps = 12/214 (5%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
Q A M+ KK + +K + T Q + + + ++EE++ L+ + +
Sbjct: 2188 QAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAA 2247
Query: 248 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAAL-----NRKVQQIEEDLEKSEE----- 397
+ +L +EE K EAE AL + + ++E+ EK ++
Sbjct: 2248 RQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEA 2307
Query: 398 -RSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLK-EARLLAEDADGKS 571
R A Q+ +Q A+E+ + L + +++ + Q +LK EA LL + + +
Sbjct: 2308 ARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKE-LA 2366
Query: 572 DEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXE 673
E +R+L ED+ ++A+ + LE E
Sbjct: 2367 QEQARRLQ--EDKEQMAQQLAEETQGFQRTLEAE 2398
Score = 37.5 bits (83), Expect = 0.049
Identities = 33/147 (22%), Positives = 71/147 (48%), Gaps = 5/147 (3%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQ---ARDANLRAEKVNEEVRELQKKLA 238
QQ+A + ++MQ ++ E+ + + +Q +D+ L+ E+ E+ + KL
Sbjct: 2490 QQEAKLLQLKSEEMQTVQQEQ--LLQETQALQQSFLSEKDSLLQRERFIEQEKA---KLE 2544
Query: 239 QVEEDLILNKNKL-EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLE-KSEERSGTA 412
Q+ +D + +L E+ + ++ E++ A + R+ + EE + K EE
Sbjct: 2545 QLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLE 2604
Query: 413 QQKLLEAQQSADENNRMCKVLENRAQQ 493
QQ+ + + A+EN R+ + L+ +Q
Sbjct: 2605 QQRRQQEELLAEENQRLREQLQLLEEQ 2631
Score = 37.1 bits (82), Expect = 0.065
Identities = 30/131 (22%), Positives = 63/131 (48%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
+ +A + +K ++ E+ +KA EQ +D +A+++ EE + Q+++ Q
Sbjct: 2514 ETQALQQSFLSEKDSLLQRERFIEQEKAKL-EQLFQDEVAKAQQLREEQQRQQQQMEQER 2572
Query: 248 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 427
+ L+ + +E+A + E E+ + + E+ QQ+E+ + EE Q+L
Sbjct: 2573 QRLVAS---MEEARRRQHEAEEGVRRKQEEL-------QQLEQQRRQQEELLAEENQRLR 2622
Query: 428 EAQQSADENNR 460
E Q +E +R
Sbjct: 2623 EQLQLLEEQHR 2633
Score = 31.1 bits (67), Expect = 4.3
Identities = 27/140 (19%), Positives = 60/140 (42%), Gaps = 2/140 (1%)
Frame = +2
Query: 125 EKDNAMDKADTCEQQARDAN-LRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLE 301
++ A+++ + + + +A LR E R+LQ ++ L + A + E
Sbjct: 2030 QRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKE 2089
Query: 302 EKEKQLTATEAEVA-ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLE 478
++ +Q E V L + + E++EE A+++ ++++ +E R+ + E
Sbjct: 2090 QELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAE 2149
Query: 479 NRAQQDEERMDQLTNQLKEA 538
+AQ + KEA
Sbjct: 2150 EQAQARAQAQAAAEKLRKEA 2169
>AK021545-1|BAB13841.1| 436|Homo sapiens protein ( Homo sapiens
cDNA FLJ11483 fis, clone HEMBA1001822, highly similar to
Mus musculus Ese2L protein mRNA. ).
Length = 436
Score = 53.2 bits (122), Expect = 9e-07
Identities = 51/207 (24%), Positives = 96/207 (46%), Gaps = 8/207 (3%)
Frame = +2
Query: 101 KKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLE 280
+KMQ + +K + D + N+ EK + + E Q++ + E K + E
Sbjct: 90 QKMQEEEPQKKLPVTFEDKRKANYERGNMELEKRRQALMEQQQR--EAERKAQKEKEEWE 147
Query: 281 QANKDLEEKE-KQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENN 457
+ ++L+E+E K+ E + +Q EE+ K ER A+Q+L ++ E
Sbjct: 148 RKQRELQEQEWKKQLELEKRLEKQRELERQREEERRKDIERREAAKQELERQRRLEWERI 207
Query: 458 RMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFV-------EDELE 616
R ++L N+ +++E + +L ++ K L E +GK ++S +L V + ELE
Sbjct: 208 RRQELL-NQKNREQEEIVRLNSKKKNLHLELEALNGKHQQISGRLQDVRLKKQTQKTELE 266
Query: 617 VAEDRVKSGDAKISXLEXELKVVGNSL 697
V + + +I L+ EL+ N L
Sbjct: 267 VLDKQCDLEIMEIKQLQQELQEYQNKL 293
>AF248540-1|AAF63600.1| 1681|Homo sapiens intersectin 2 protein.
Length = 1681
Score = 53.2 bits (122), Expect = 9e-07
Identities = 51/207 (24%), Positives = 96/207 (46%), Gaps = 8/207 (3%)
Frame = +2
Query: 101 KKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLE 280
+KMQ + +K + D + N+ EK + + E Q++ + E K + E
Sbjct: 359 QKMQEEEPQKKLPVTFEDKRKANYERGNMELEKRRQALMEQQQR--EAERKAQKEKEEWE 416
Query: 281 QANKDLEEKE-KQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENN 457
+ ++L+E+E K+ E + +Q EE+ K ER A+Q+L ++ E
Sbjct: 417 RKQRELQEQEWKKQLELEKRLEKQRELERQREEERRKDIERREAAKQELERQRRLEWERI 476
Query: 458 RMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFV-------EDELE 616
R ++L N+ +++E + +L ++ K L E +GK ++S +L V + ELE
Sbjct: 477 RRQELL-NQKNREQEEIVRLNSKKKNLHLELEALNGKHQQISGRLQDVRLKKQTQKTELE 535
Query: 617 VAEDRVKSGDAKISXLEXELKVVGNSL 697
V + + +I L+ EL+ N L
Sbjct: 536 VLDKQCDLEIMEIKQLQQELQEYQNKL 562
Score = 37.1 bits (82), Expect = 0.065
Identities = 33/153 (21%), Positives = 71/153 (46%), Gaps = 2/153 (1%)
Frame = +2
Query: 71 QKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEE 250
+K +K+++ A++ E + + + D+ Q ++ LR E N + L++ L +++
Sbjct: 598 EKEELCQRLKEQLDALEKETASKLSEMDSFNNQLKE--LR-ETYNTQQLALEQ-LYKIKR 653
Query: 251 DLI--LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL 424
D + + + +LE K E E A + + +++ EE+ +K + T Q+K+
Sbjct: 654 DKLKEIERKRLELMQKKKLEDEAARKAKQGKENLWKENLRKEEEEKQKRLQEEKT-QEKI 712
Query: 425 LEAQQSADENNRMCKVLENRAQQDEERMDQLTN 523
E ++ A+E R K ++ E L N
Sbjct: 713 QEEERKAEEKQRKDKDTLKAEEKKRETASVLVN 745
>AF182199-1|AAF59904.1| 1248|Homo sapiens intersectin 2 short
isoform protein.
Length = 1248
Score = 53.2 bits (122), Expect = 9e-07
Identities = 51/207 (24%), Positives = 96/207 (46%), Gaps = 8/207 (3%)
Frame = +2
Query: 101 KKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLE 280
+KMQ + +K + D + N+ EK + + E Q++ + E K + E
Sbjct: 347 QKMQEEEPQKKLPVTFEDKRKANYERGNMELEKRRQALMEQQQR--EAERKAQKEKEEWE 404
Query: 281 QANKDLEEKE-KQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENN 457
+ ++L+E+E K+ E + +Q EE+ K ER A+Q+L ++ E
Sbjct: 405 RKQRELQEQEWKKQLELEKRLEKQRELERQREEERRKDIERREAAKQELERQRRLEWERI 464
Query: 458 RMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFV-------EDELE 616
R ++L N+ +++E + +L ++ K L E +GK ++S +L V + ELE
Sbjct: 465 RRQELL-NQKNREQEEIVRLNSKKKNLHLELEALNGKHQQISGRLQDVRLKKQTQKTELE 523
Query: 617 VAEDRVKSGDAKISXLEXELKVVGNSL 697
V + + +I L+ EL+ N L
Sbjct: 524 VLDKQCDLEIMEIKQLQQELQEYQNKL 550
Score = 29.9 bits (64), Expect = 9.8
Identities = 30/114 (26%), Positives = 49/114 (42%), Gaps = 8/114 (7%)
Frame = +2
Query: 206 EEVRELQKKLAQVEEDLI-LNKNKLEQAN-KDLEEKEKQLTATEAEVAALNRKVQQIEED 379
+E+RE E L + ++KL++ K LE +K+ EA A K +E+
Sbjct: 647 KELRETYNTQQLALEQLYKIKRDKLKEIERKRLELMQKKKLEDEAARKAKQGKENLWKEN 706
Query: 380 LEKSEE------RSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 523
L K EE + Q+K+ E ++ A+E R K ++ E L N
Sbjct: 707 LRKEEEEKQKRLQEEKTQEKIQEEERKAEEKQRKDKDTLKAEEKKRETASVLVN 760
>AF182198-1|AAF59903.1| 1696|Homo sapiens intersectin 2 long isoform
protein.
Length = 1696
Score = 53.2 bits (122), Expect = 9e-07
Identities = 51/207 (24%), Positives = 96/207 (46%), Gaps = 8/207 (3%)
Frame = +2
Query: 101 KKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLE 280
+KMQ + +K + D + N+ EK + + E Q++ + E K + E
Sbjct: 347 QKMQEEEPQKKLPVTFEDKRKANYERGNMELEKRRQALMEQQQR--EAERKAQKEKEEWE 404
Query: 281 QANKDLEEKE-KQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENN 457
+ ++L+E+E K+ E + +Q EE+ K ER A+Q+L ++ E
Sbjct: 405 RKQRELQEQEWKKQLELEKRLEKQRELERQREEERRKDIERREAAKQELERQRRLEWERI 464
Query: 458 RMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFV-------EDELE 616
R ++L N+ +++E + +L ++ K L E +GK ++S +L V + ELE
Sbjct: 465 RRQELL-NQKNREQEEIVRLNSKKKNLHLELEALNGKHQQISGRLQDVRLKKQTQKTELE 523
Query: 617 VAEDRVKSGDAKISXLEXELKVVGNSL 697
V + + +I L+ EL+ N L
Sbjct: 524 VLDKQCDLEIMEIKQLQQELQEYQNKL 550
Score = 29.9 bits (64), Expect = 9.8
Identities = 30/114 (26%), Positives = 49/114 (42%), Gaps = 8/114 (7%)
Frame = +2
Query: 206 EEVRELQKKLAQVEEDLI-LNKNKLEQAN-KDLEEKEKQLTATEAEVAALNRKVQQIEED 379
+E+RE E L + ++KL++ K LE +K+ EA A K +E+
Sbjct: 647 KELRETYNTQQLALEQLYKIKRDKLKEIERKRLELMQKKKLEDEAARKAKQGKENLWKEN 706
Query: 380 LEKSEE------RSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 523
L K EE + Q+K+ E ++ A+E R K ++ E L N
Sbjct: 707 LRKEEEEKQKRLQEEKTQEKIQEEERKAEEKQRKDKDTLKAEEKKRETASVLVN 760
>AC009228-1|AAX93122.1| 1329|Homo sapiens unknown protein.
Length = 1329
Score = 53.2 bits (122), Expect = 9e-07
Identities = 51/207 (24%), Positives = 96/207 (46%), Gaps = 8/207 (3%)
Frame = +2
Query: 101 KKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLE 280
+KMQ + +K + D + N+ EK + + E Q++ + E K + E
Sbjct: 347 QKMQEEEPQKKLPVTFEDKRKANYERGNMELEKRRQALMEQQQR--EAERKAQKEKEEWE 404
Query: 281 QANKDLEEKE-KQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENN 457
+ ++L+E+E K+ E + +Q EE+ K ER A+Q+L ++ E
Sbjct: 405 RKQRELQEQEWKKQLELEKRLEKQRELERQREEERRKDIERREAAKQELERQRRLEWERI 464
Query: 458 RMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFV-------EDELE 616
R ++L N+ +++E + +L ++ K L E +GK ++S +L V + ELE
Sbjct: 465 RRQELL-NQKNREQEEIVRLNSKKKNLHLELEALNGKHQQISGRLQDVRLKKQTQKTELE 523
Query: 617 VAEDRVKSGDAKISXLEXELKVVGNSL 697
V + + +I L+ EL+ N L
Sbjct: 524 VLDKQCDLEIMEIKQLQQELQEYQNKL 550
Score = 29.9 bits (64), Expect = 9.8
Identities = 30/114 (26%), Positives = 49/114 (42%), Gaps = 8/114 (7%)
Frame = +2
Query: 206 EEVRELQKKLAQVEEDLI-LNKNKLEQAN-KDLEEKEKQLTATEAEVAALNRKVQQIEED 379
+E+RE E L + ++KL++ K LE +K+ EA A K +E+
Sbjct: 647 KELRETYNTQQLALEQLYKIKRDKLKEIERKRLELMQKKKLEDEAARKAKQGKENLWKEN 706
Query: 380 LEKSEE------RSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 523
L K EE + Q+K+ E ++ A+E R K ++ E L N
Sbjct: 707 LRKEEEEKQKRLQEEKTQEKIQEEERKAEEKQRKDKDTLKAEEKKRETASVLVN 760
>AB033082-1|BAA86570.1| 1676|Homo sapiens KIAA1256 protein protein.
Length = 1676
Score = 53.2 bits (122), Expect = 9e-07
Identities = 51/207 (24%), Positives = 96/207 (46%), Gaps = 8/207 (3%)
Frame = +2
Query: 101 KKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLE 280
+KMQ + +K + D + N+ EK + + E Q++ + E K + E
Sbjct: 354 QKMQEEEPQKKLPVTFEDKRKANYERGNMELEKRRQALMEQQQR--EAERKAQKEKEEWE 411
Query: 281 QANKDLEEKE-KQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENN 457
+ ++L+E+E K+ E + +Q EE+ K ER A+Q+L ++ E
Sbjct: 412 RKQRELQEQEWKKQLELEKRLEKQRELERQREEERRKDIERREAAKQELERQRRLEWERI 471
Query: 458 RMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFV-------EDELE 616
R ++L N+ +++E + +L ++ K L E +GK ++S +L V + ELE
Sbjct: 472 RRQELL-NQKNREQEEIVRLNSKKKNLHLELEALNGKHQQISGRLQDVRLKKQTQKTELE 530
Query: 617 VAEDRVKSGDAKISXLEXELKVVGNSL 697
V + + +I L+ EL+ N L
Sbjct: 531 VLDKQCDLEIMEIKQLQQELQEYQNKL 557
Score = 37.1 bits (82), Expect = 0.065
Identities = 33/153 (21%), Positives = 71/153 (46%), Gaps = 2/153 (1%)
Frame = +2
Query: 71 QKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEE 250
+K +K+++ A++ E + + + D+ Q ++ LR E N + L++ L +++
Sbjct: 593 EKEELCQRLKEQLDALEKETASKLSEMDSFNNQLKE--LR-ETYNTQQLALEQ-LYKIKR 648
Query: 251 DLI--LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL 424
D + + + +LE K E E A + + +++ EE+ +K + T Q+K+
Sbjct: 649 DKLKEIERKRLELMQKKKLEDEAARKAKQGKENLWKENLRKEEEEKQKRLQEEKT-QEKI 707
Query: 425 LEAQQSADENNRMCKVLENRAQQDEERMDQLTN 523
E ++ A+E R K ++ E L N
Sbjct: 708 QEEERKAEEKQRKDKDTLKAEEKKRETASVLVN 740
>S67240-1|AAB28951.1| 330|Homo sapiens smooth muscle myosin heavy
chain isoform SM1 protein.
Length = 330
Score = 52.8 bits (121), Expect = 1e-06
Identities = 38/200 (19%), Positives = 96/200 (48%), Gaps = 5/200 (2%)
Frame = +2
Query: 95 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 274
++ ++ ++ E + + + R A +AE+++ E+ ++ AQ E + +
Sbjct: 92 LEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELAT-ERTTAQKNESA---RQQ 147
Query: 275 LEQANKDLEEKEKQLTAT-----EAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 439
LE+ NK+L K ++ ++ +AAL K+ Q+EE +E+ A + L + +
Sbjct: 148 LERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDK 207
Query: 440 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 619
E + A+Q +E+ ++ +K+ + E+A+ +S ++ ++ EL+
Sbjct: 208 KLKEILLQVEDERKMAEQYKEQAEKGNAGVKQLKRQLEEAEEESQRINANRRKLQRELDE 267
Query: 620 AEDRVKSGDAKISXLEXELK 679
A + ++ +++ L+ +L+
Sbjct: 268 ATESNEAMGREVNALKSKLR 287
Score = 46.8 bits (106), Expect = 8e-05
Identities = 47/197 (23%), Positives = 93/197 (47%), Gaps = 2/197 (1%)
Frame = +2
Query: 92 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEE-VRELQKKLAQVEEDLILNK 268
AIK+ + KD + D + +RD K NE+ + L+ L Q++EDL +
Sbjct: 1 AIKQLRKLQAQMKDFQRELEDA--RASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAE 58
Query: 269 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSAD 448
+QA+ + EE ++L ++ + AL + +++E + + EE LE +Q
Sbjct: 59 RARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEE--------LEEEQGNM 110
Query: 449 ENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAED 628
E + +R ++ ++ +QL+N+L R A+ + ++ R+ + +L E
Sbjct: 111 E------AMSDRVRKATQQAEQLSNELATERTTAQKNESARQQLERQNKELRSKLHEMEG 164
Query: 629 RVKSG-DAKISXLEXEL 676
VKS + I+ LE ++
Sbjct: 165 AVKSKFKSTIAALEAKI 181
Score = 37.9 bits (84), Expect = 0.037
Identities = 33/129 (25%), Positives = 65/129 (50%), Gaps = 1/129 (0%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
++K A ++K+K + +K D+ EQ +AEK N V++L+++L + E
Sbjct: 193 REKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKE----QAEKGNAGVKQLKRQLEEAE 248
Query: 248 ED-LILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL 424
E+ +N N+ + ++L+E + A EV AL K+++ E RSG +++
Sbjct: 249 EESQRINANR-RKLQRELDEATESNEAMGREVNALKSKLRRGNETSFVPSRRSG--GRRV 305
Query: 425 LEAQQSADE 451
+E ++E
Sbjct: 306 IENADGSEE 314
>S67238-1|AAB28950.1| 296|Homo sapiens smooth muscle myosin heavy
chain isoform SM2 protein.
Length = 296
Score = 52.8 bits (121), Expect = 1e-06
Identities = 38/200 (19%), Positives = 96/200 (48%), Gaps = 5/200 (2%)
Frame = +2
Query: 95 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 274
++ ++ ++ E + + + R A +AE+++ E+ ++ AQ E + +
Sbjct: 92 LEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELAT-ERTTAQKNESA---RQQ 147
Query: 275 LEQANKDLEEKEKQLTAT-----EAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 439
LE+ NK+L K ++ ++ +AAL K+ Q+EE +E+ A + L + +
Sbjct: 148 LERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDK 207
Query: 440 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 619
E + A+Q +E+ ++ +K+ + E+A+ +S ++ ++ EL+
Sbjct: 208 KLKEILLQVEDERKMAEQYKEQAEKGNAGVKQLKRQLEEAEEESQRINANRRKLQRELDE 267
Query: 620 AEDRVKSGDAKISXLEXELK 679
A + ++ +++ L+ +L+
Sbjct: 268 ATESNEAMGREVNALKSKLR 287
Score = 46.8 bits (106), Expect = 8e-05
Identities = 47/197 (23%), Positives = 93/197 (47%), Gaps = 2/197 (1%)
Frame = +2
Query: 92 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEE-VRELQKKLAQVEEDLILNK 268
AIK+ + KD + D + +RD K NE+ + L+ L Q++EDL +
Sbjct: 1 AIKQLRKLQAQMKDFQRELEDA--RASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAE 58
Query: 269 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSAD 448
+QA+ + EE ++L ++ + AL + +++E + + EE LE +Q
Sbjct: 59 RARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEE--------LEEEQGNM 110
Query: 449 ENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAED 628
E + +R ++ ++ +QL+N+L R A+ + ++ R+ + +L E
Sbjct: 111 E------AMSDRVRKATQQAEQLSNELATERTTAQKNESARQQLERQNKELRSKLHEMEG 164
Query: 629 RVKSG-DAKISXLEXEL 676
VKS + I+ LE ++
Sbjct: 165 AVKSKFKSTIAALEAKI 181
Score = 34.3 bits (75), Expect = 0.46
Identities = 27/100 (27%), Positives = 52/100 (52%), Gaps = 1/100 (1%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
++K A ++K+K + +K D+ EQ +AEK N V++L+++L + E
Sbjct: 193 REKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKE----QAEKGNAGVKQLKRQLEEAE 248
Query: 248 ED-LILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQ 364
E+ +N N+ + ++L+E + A EV AL K++
Sbjct: 249 EESQRINANR-RKLQRELDEATESNEAMGREVNALKSKLR 287
>M21665-1|AAA36345.1| 524|Homo sapiens protein ( Human beta-myosin
heavy chain mRNA, 3' end. ).
Length = 524
Score = 52.8 bits (121), Expect = 1e-06
Identities = 39/190 (20%), Positives = 79/190 (41%)
Frame = +2
Query: 161 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 340
+ + D + E+ N L KK ++ L K K E++ +LE +K+ + E+
Sbjct: 11 QNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTEL 70
Query: 341 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLT 520
L ++ E LE + + Q+++ + + + + LE +Q E +L
Sbjct: 71 FKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQ 130
Query: 521 NQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLK 700
+ L+EA E +GK + +L F + + E+ + + + L+VV +
Sbjct: 131 SALEEAEASLEHEEGKI--LRAQLEFNQIKAEIERNVAEKDEEMEQAKRNHLRVVDSLQT 188
Query: 701 SLEVSEXKAN 730
SL+ N
Sbjct: 189 SLDAETRSRN 198
Score = 48.4 bits (110), Expect = 3e-05
Identities = 53/228 (23%), Positives = 111/228 (48%), Gaps = 14/228 (6%)
Frame = +2
Query: 86 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAE-KVNEEVRELQKKLAQVEEDLIL 262
++ ++K+++A K+E +A+++A+ + LRA+ + N+ E+++ +A+ +E+
Sbjct: 115 LEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERNVAEKDEE--- 171
Query: 263 NKNKLEQANKD-LEEKEKQLTATEAEVAALN---RKVQQIEEDLEKSEERSGTAQQKLLE 430
+EQA ++ L + T+ +AE + N R +++E DL + E + A + E
Sbjct: 172 ----MEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAE 227
Query: 431 AQQSADENNRMCK----VLENRAQQDEERMDQLT-----NQLKEARLLAEDADGKSDEVS 583
AQ+ + K L++ + +++ + + N L +A L A + E S
Sbjct: 228 AQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERS 287
Query: 584 RKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXKA 727
RKLA E EL +RV+ ++ + L + K + L L+ +A
Sbjct: 288 RKLA--EQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEA 333
>BC132736-1|AAI32737.1| 1843|Homo sapiens coiled-coil domain
containing 88A protein.
Length = 1843
Score = 52.8 bits (121), Expect = 1e-06
Identities = 55/217 (25%), Positives = 103/217 (47%), Gaps = 18/217 (8%)
Frame = +2
Query: 83 TMDAIKK-KMQAMKLEKDNAMDKADTCE-----QQARDANLRAEKVNEEVRELQKKLAQV 244
T+D+ K Q LEK+N+ + E + + A+++ ++ E +EL+ + Q+
Sbjct: 678 TLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQL 737
Query: 245 EEDLILNK------NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSG 406
++ L L K +LE + + L+ + ++L T + N+K+QQ+E +L+ E +
Sbjct: 738 KKGLELLKASFKKTERLEVSYQGLDIENQRLQKT---LENSNKKIQQLESELQDLEMENQ 794
Query: 407 TAQQKLLEAQQSA---DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDE 577
T Q+ L E + S+ ++ + K LE Q E+ QL + K R AE D +E
Sbjct: 795 TLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEE 854
Query: 578 VSRKLAFVEDELEVAEDRV---KSGDAKISXLEXELK 679
+ K+ +E E + + K ++ LE E K
Sbjct: 855 NNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENK 891
Score = 44.4 bits (100), Expect = 4e-04
Identities = 35/215 (16%), Positives = 102/215 (47%), Gaps = 3/215 (1%)
Frame = +2
Query: 89 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE---EDLI 259
+ +KK ++ +K + K + E + ++ +++ + + KK+ Q+E +DL
Sbjct: 735 EQLKKGLELLKA----SFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLE 790
Query: 260 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 439
+ L++ ++L+ K+L E E +L ++ Q+E+D ++ E+ + +Q+
Sbjct: 791 MENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDT 850
Query: 440 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 619
+ +ENN V +++ + + + KE+ + ++ + ++ E+ ++ L
Sbjct: 851 TLEENN----VKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKTLVT 906
Query: 620 AEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXK 724
+ + S K + +L+ + + L+ + +++ +
Sbjct: 907 LREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKER 941
>AL121586-7|CAB89415.1| 2442|Homo sapiens centrosomal protein 250kDa
protein.
Length = 2442
Score = 52.8 bits (121), Expect = 1e-06
Identities = 46/186 (24%), Positives = 89/186 (47%), Gaps = 7/186 (3%)
Frame = +2
Query: 173 RDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALN 352
RD E E + ELQ+ Q+E+ +L+ ++ + E L+ E E+ L
Sbjct: 1732 RDKEKEVECQQEHIHELQELKDQLEQ-------QLQGLHRKVGETSLLLSQREQEIVVLQ 1784
Query: 353 RKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQ---DEERM----D 511
QQ++E E+ E + + Q +L EAQ++ + ++ + L+ QQ EER+ D
Sbjct: 1785 ---QQLQEAREQGELKEQSLQSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVKEKAD 1841
Query: 512 QLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGN 691
L L++A + ++ G+ + + +E+EL V RV++ + + L E +
Sbjct: 1842 ALQGALEQAHMTLKERHGELQDHKEQARRLEEELAVEGRRVQALEEVLGDLRAESREQEK 1901
Query: 692 SLKSLE 709
+L +L+
Sbjct: 1902 ALLALQ 1907
Score = 45.6 bits (103), Expect = 2e-04
Identities = 49/226 (21%), Positives = 93/226 (41%), Gaps = 7/226 (3%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
Q + A + +QA +E A E+ R A + NEEV +++ ++
Sbjct: 1347 QAAKENLTAQVEHLQAAVVEARAQASAAGILEEDLRTARSALKLKNEEVESERERAQALQ 1406
Query: 248 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 427
E L + + ++L + L E EV L ++Q++E+ E + L
Sbjct: 1407 EQGELKVAQGKALQENLALLTQTLAEREEEVETLRGQIQELEKQREMQKAALELLSLDLK 1466
Query: 428 EAQQSAD-------ENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSR 586
+ Q D E + VLE+ +ER +LT Q ++ R L +D + + + +
Sbjct: 1467 KRNQEVDLQQEQIQELEKCRSVLEHLPMAVQEREQKLTVQREQIRELEKDRETQRNVLEH 1526
Query: 587 KLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXK 724
+L ELE + ++S ++ L+ +L + LE + K
Sbjct: 1527 QLL----ELEKKDQMIESQRGQVQDLKKQLVTLECLALELEENHHK 1568
Score = 45.2 bits (102), Expect = 2e-04
Identities = 51/214 (23%), Positives = 99/214 (46%), Gaps = 20/214 (9%)
Frame = +2
Query: 71 QKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAE--KVNEEVRELQKKLAQV 244
+ A +D + + + L + N +A + + A L+A+ + EE E+QKKL++
Sbjct: 640 RNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSES 699
Query: 245 EEDLILNKNKLEQANKDLEEKEKQLT-------ATEAEVAALNRKVQQIEEDLEK-SEER 400
+LEQ +++ + +E+ L A E AAL ++Q +E D + +E+
Sbjct: 700 RHQQEAATTQLEQLHQEAKRQEEVLARAVQEKEALVREKAALEVRLQAVERDRQDLAEQL 759
Query: 401 SGTAQQK-LLEAQQ-SADENNRMCKVLENRAQQDEERMDQLTNQLK-EARLL-------A 550
G + K LLE+ A + N + +V + + + + + Q ++ E R L
Sbjct: 760 QGLSSAKELLESSLFEAQQQNSVIEVTKGQLEVQIQTVTQAKEVIQGEVRCLKLELDTER 819
Query: 551 EDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAK 652
A+ + D +R+LA E E + A ++ K+ K
Sbjct: 820 SQAEQERDAAARQLAQAEQEGKTALEQQKAAHEK 853
Score = 44.8 bits (101), Expect = 3e-04
Identities = 42/213 (19%), Positives = 94/213 (44%)
Frame = +2
Query: 71 QKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEE 250
Q+ ++A++++ Q + +++ +KAD + A++ ++ + E+++ +++ ++EE
Sbjct: 1814 QRDQELEALQQEQQQAQGQEERVKEKADALQGALEQAHMTLKERHGELQDHKEQARRLEE 1873
Query: 251 DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLE 430
+L + +++ + L + + E + AL QQ E ++ E + Q L+
Sbjct: 1874 ELAVEGRRVQALEEVLGDLRAESREQEKALLALQ---QQCAEQAQEHEVETRALQDSWLQ 1930
Query: 431 AQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDE 610
AQ E ++ + L RA+ R +Q + AR AE + L E
Sbjct: 1931 AQAVLKERDQELEAL--RAESQSSR-----HQEEAARARAEALQEALGKAHAALQGKEQH 1983
Query: 611 LEVAEDRVKSGDAKISXLEXELKVVGNSLKSLE 709
L + +S +A + L+ L + LE
Sbjct: 1984 LLEQAELSRSLEASTATLQASLDACQAHSRQLE 2016
Score = 40.3 bits (90), Expect = 0.007
Identities = 57/243 (23%), Positives = 108/243 (44%), Gaps = 29/243 (11%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQAR--DANLRAEKVN--EEVREL--QK 229
Q++ T D ++++ Q + L+K+ D +Q + + +L K++ E REL Q+
Sbjct: 1645 QKEHLTQD-LERRDQELMLQKERIQVLEDQRTRQTKILEEDLEQIKLSLRERGRELTTQR 1703
Query: 230 KLAQ--VEEDLILNK---NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSE 394
+L Q EE +K LE L +KEK++ + + L Q+E+ L+
Sbjct: 1704 QLMQERAEEGKGPSKAQRGSLEHMKLILRDKEKEVECQQEHIHELQELKDQLEQQLQGLH 1763
Query: 395 ERSGTA-------QQKLLEAQQSADENNRMCKVLEN--RAQQDEER--MDQLTNQLKEAR 541
+ G +Q+++ QQ E ++ E ++Q DE + + Q +L+ +
Sbjct: 1764 RKVGETSLLLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQRALAQRDQELEALQ 1823
Query: 542 LLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKIS-------XLEXELKVVGNSLK 700
+ A G+ + V K ++ LE A +K ++ LE EL V G ++
Sbjct: 1824 QEQQQAQGQEERVKEKADALQGALEQAHMTLKERHGELQDHKEQARRLEEELAVEGRRVQ 1883
Query: 701 SLE 709
+LE
Sbjct: 1884 ALE 1886
Score = 37.9 bits (84), Expect = 0.037
Identities = 33/159 (20%), Positives = 75/159 (47%), Gaps = 3/159 (1%)
Frame = +2
Query: 233 LAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTA 412
L ++ +DL + + +++ E++LT TEAE + ++ ++Q ++ L +++E
Sbjct: 1245 LHKLHQDLWKTQQTRDVLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQE----- 1299
Query: 413 QQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSD---EVS 583
++ E +Q++ LE+ + E M L ++L+ A L +A G+ +
Sbjct: 1300 EKSKWEGKQNS---------LESELMELHETMASLQSRLRRAELQRMEAQGERELLQAAK 1350
Query: 584 RKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLK 700
L + L+ A ++ + LE +L+ ++LK
Sbjct: 1351 ENLTAQVEHLQAAVVEARAQASAAGILEEDLRTARSALK 1389
Score = 37.5 bits (83), Expect = 0.049
Identities = 42/208 (20%), Positives = 94/208 (45%), Gaps = 3/208 (1%)
Frame = +2
Query: 113 AMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANK 292
+ +LE+ K ++Q L+ + + E REL++ Q +DL + + +
Sbjct: 945 SQQLERLRQDMKVQKLKEQETTGILQTQ-LQEAQRELKEAARQHRDDLAALQEESSSLLQ 1003
Query: 293 DLEEKEKQLTATEAEVAALNRKVQQIEEDLEKS--EERSGTAQQKLLEAQQSADENNRMC 466
D + +KQ+ ++++ A + + +E+++++ E + QK LE ++++ + M
Sbjct: 1004 DKMDLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRIQKELEREKASLTLSLME 1063
Query: 467 KVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGD 646
K Q+ + + Q +L R ++A G+ E+S ++ + E++ E + +
Sbjct: 1064 KEQRLLVLQEADSIRQ--QELSALRQDMQEAQGEQKELSAQMELLRQEVKEKEADFLAQE 1121
Query: 647 AK-ISXLEXELKVVGNSLKSLEVSEXKA 727
A+ + LE SL E KA
Sbjct: 1122 AQLLEELEASHITEQQLRASLWAQEAKA 1149
Score = 34.7 bits (76), Expect = 0.35
Identities = 40/208 (19%), Positives = 95/208 (45%), Gaps = 4/208 (1%)
Frame = +2
Query: 119 KLEKDNAMDKADTCEQQARDANLRAEKVN--EEVRELQKKLAQVEEDLILNKNKLEQANK 292
+L++ + D Q ++L +K++ ++V +L+ +L ++ L + ++++ +
Sbjct: 979 ELKEAARQHRDDLAALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLR 1038
Query: 293 DLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKV 472
+ +E + E E A+L + + E+ L +E QQ+L +Q E
Sbjct: 1039 ETQEYNRIQKELEREKASLTLSLMEKEQRLLVLQEADSIRQQELSALRQDMQE------- 1091
Query: 473 LENRAQQDEERMDQLTNQL--KEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGD 646
+ ++ +M+ L ++ KEA LA++A +E+ E +L + + + +
Sbjct: 1092 AQGEQKELSAQMELLRQEVKEKEADFLAQEAQ-LLEELEAS-HITEQQLRAS---LWAQE 1146
Query: 647 AKISXLEXELKVVGNSLKSLEVSEXKAN 730
AK + L+ L+ + L++L + N
Sbjct: 1147 AKAAQLQLRLRSTESQLEALAAEQQPGN 1174
Score = 33.5 bits (73), Expect = 0.80
Identities = 21/121 (17%), Positives = 60/121 (49%)
Frame = +2
Query: 89 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 268
+ + +K A +++ +N + + Q+ + +R +++ VRELQ LAQ E++++ +
Sbjct: 2058 EQLLEKSLAQRVQ-ENMIQEKQNLGQEREEEEIRG--LHQSVRELQLTLAQKEQEILELR 2114
Query: 269 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSAD 448
++ N + + + E + L+ +++ +LE+ + + + +E ++ A
Sbjct: 2115 ETQQRNNLEALPHSHKTSPMEEQSLKLDSLEPRLQRELERLQAALRQTEAREIEWREKAQ 2174
Query: 449 E 451
+
Sbjct: 2175 D 2175
Score = 30.7 bits (66), Expect = 5.6
Identities = 25/97 (25%), Positives = 50/97 (51%)
Frame = +2
Query: 161 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 340
E Q RD +++++ E++ ELQ++ + +DL +L + ++ E Q T +
Sbjct: 1624 ELQERDQEVKSQR--EQIEELQRQKEHLTQDLERRDQELMLQKERIQVLEDQRT---RQT 1678
Query: 341 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADE 451
L ++QI+ L + R T Q++L+ Q+ A+E
Sbjct: 1679 KILEEDLEQIKLSL-RERGRELTTQRQLM--QERAEE 1712
Score = 30.3 bits (65), Expect = 7.4
Identities = 41/174 (23%), Positives = 69/174 (39%), Gaps = 16/174 (9%)
Frame = +2
Query: 206 EEVRELQK-KLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDL 382
E RE Q+ L + DL +L+ + + + E T E+ +++V+ E +
Sbjct: 1580 EGQRETQRVALTHLTLDLEERSQELQAQSSQIHDLESHSTVLARELQERDQEVKSQREQI 1639
Query: 383 EKSEERSGTAQQKLLEAQQS-----------ADENNRMCKVLENRAQQDE----ERMDQL 517
E+ + + Q L Q D+ R K+LE +Q + ER +L
Sbjct: 1640 EELQRQKEHLTQDLERRDQELMLQKERIQVLEDQRTRQTKILEEDLEQIKLSLRERGREL 1699
Query: 518 TNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELK 679
T Q + + AE+ G S L ++ L E V+ I L+ ELK
Sbjct: 1700 TTQRQLMQERAEEGKGPSKAQRGSLEHMKLILRDKEKEVECQQEHIHELQ-ELK 1752
>AF049105-1|AAC07988.1| 2442|Homo sapiens centrosomal Nek2-associated
protein 1 protein.
Length = 2442
Score = 52.8 bits (121), Expect = 1e-06
Identities = 46/186 (24%), Positives = 89/186 (47%), Gaps = 7/186 (3%)
Frame = +2
Query: 173 RDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALN 352
RD E E + ELQ+ Q+E+ +L+ ++ + E L+ E E+ L
Sbjct: 1732 RDKEKEVECQQEHIHELQELKDQLEQ-------QLQGLHRKVGETSLLLSQREQEIVVLQ 1784
Query: 353 RKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQ---DEERM----D 511
QQ++E E+ E + + Q +L EAQ++ + ++ + L+ QQ EER+ D
Sbjct: 1785 ---QQLQEAREQGELKEQSLQSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVKEKAD 1841
Query: 512 QLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGN 691
L L++A + ++ G+ + + +E+EL V RV++ + + L E +
Sbjct: 1842 ALQGALEQAHMTLKERHGELQDHKEQARRLEEELAVEGRRVQALEEVLGDLRAESREQEK 1901
Query: 692 SLKSLE 709
+L +L+
Sbjct: 1902 ALLALQ 1907
Score = 45.6 bits (103), Expect = 2e-04
Identities = 49/226 (21%), Positives = 93/226 (41%), Gaps = 7/226 (3%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
Q + A + +QA +E A E+ R A + NEEV +++ ++
Sbjct: 1347 QAAKENLTAQVEHLQAAVVEARAQASAAGILEEDLRTARSALKLKNEEVESERERAQALQ 1406
Query: 248 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 427
E L + + ++L + L E EV L ++Q++E+ E + L
Sbjct: 1407 EQGELKVAQGKALQENLALLTQTLAEREEEVETLRGQIQELEKQREMQKAALELLSLDLK 1466
Query: 428 EAQQSAD-------ENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSR 586
+ Q D E + VLE+ +ER +LT Q ++ R L +D + + + +
Sbjct: 1467 KRNQEVDLQQEQIQELEKCRSVLEHLPMAVQEREQKLTVQREQIRELEKDRETQRNVLEH 1526
Query: 587 KLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXK 724
+L ELE + ++S ++ L+ +L + LE + K
Sbjct: 1527 QLL----ELEKKDQMIESQRGQVQDLKKQLVTLECLALELEENHHK 1568
Score = 45.2 bits (102), Expect = 2e-04
Identities = 51/214 (23%), Positives = 99/214 (46%), Gaps = 20/214 (9%)
Frame = +2
Query: 71 QKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAE--KVNEEVRELQKKLAQV 244
+ A +D + + + L + N +A + + A L+A+ + EE E+QKKL++
Sbjct: 640 RNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSES 699
Query: 245 EEDLILNKNKLEQANKDLEEKEKQLT-------ATEAEVAALNRKVQQIEEDLEK-SEER 400
+LEQ +++ + +E+ L A E AAL ++Q +E D + +E+
Sbjct: 700 RHQQEAATTQLEQLHQEAKRQEEVLARAVQEKEALVREKAALEVRLQAVERDRQDLAEQL 759
Query: 401 SGTAQQK-LLEAQQ-SADENNRMCKVLENRAQQDEERMDQLTNQLK-EARLL-------A 550
G + K LLE+ A + N + +V + + + + + Q ++ E R L
Sbjct: 760 QGLSSAKELLESSLFEAQQQNSVIEVTKGQLEVQIQTVTQAKEVIQGEVRCLKLELDTER 819
Query: 551 EDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAK 652
A+ + D +R+LA E E + A ++ K+ K
Sbjct: 820 SQAEQERDAAARQLAQAEQEGKTALEQQKAAHEK 853
Score = 44.8 bits (101), Expect = 3e-04
Identities = 42/213 (19%), Positives = 94/213 (44%)
Frame = +2
Query: 71 QKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEE 250
Q+ ++A++++ Q + +++ +KAD + A++ ++ + E+++ +++ ++EE
Sbjct: 1814 QRDQELEALQQEQQQAQGQEERVKEKADALQGALEQAHMTLKERHGELQDHKEQARRLEE 1873
Query: 251 DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLE 430
+L + +++ + L + + E + AL QQ E ++ E + Q L+
Sbjct: 1874 ELAVEGRRVQALEEVLGDLRAESREQEKALLALQ---QQCAEQAQEHEVETRALQDSWLQ 1930
Query: 431 AQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDE 610
AQ E ++ + L RA+ R +Q + AR AE + L E
Sbjct: 1931 AQAVLKERDQELEAL--RAESQSSR-----HQEEAARARAEALQEALGKAHAALQGKEQH 1983
Query: 611 LEVAEDRVKSGDAKISXLEXELKVVGNSLKSLE 709
L + +S +A + L+ L + LE
Sbjct: 1984 LLEQAELSRSLEASTATLQASLDACQAHSRQLE 2016
Score = 40.3 bits (90), Expect = 0.007
Identities = 57/243 (23%), Positives = 108/243 (44%), Gaps = 29/243 (11%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQAR--DANLRAEKVN--EEVREL--QK 229
Q++ T D ++++ Q + L+K+ D +Q + + +L K++ E REL Q+
Sbjct: 1645 QKEHLTQD-LERRDQELMLQKERIQVLEDQRTRQTKILEEDLEQIKLSLRERGRELTTQR 1703
Query: 230 KLAQ--VEEDLILNK---NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSE 394
+L Q EE +K LE L +KEK++ + + L Q+E+ L+
Sbjct: 1704 QLMQERAEEGKGPSKAQRGSLEHMKLILRDKEKEVECQQEHIHELQELKDQLEQQLQGLH 1763
Query: 395 ERSGTA-------QQKLLEAQQSADENNRMCKVLEN--RAQQDEER--MDQLTNQLKEAR 541
+ G +Q+++ QQ E ++ E ++Q DE + + Q +L+ +
Sbjct: 1764 RKVGETSLLLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQRALAQRDQELEALQ 1823
Query: 542 LLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKIS-------XLEXELKVVGNSLK 700
+ A G+ + V K ++ LE A +K ++ LE EL V G ++
Sbjct: 1824 QEQQQAQGQEERVKEKADALQGALEQAHMTLKERHGELQDHKEQARRLEEELAVEGRRVQ 1883
Query: 701 SLE 709
+LE
Sbjct: 1884 ALE 1886
Score = 37.9 bits (84), Expect = 0.037
Identities = 33/159 (20%), Positives = 75/159 (47%), Gaps = 3/159 (1%)
Frame = +2
Query: 233 LAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTA 412
L ++ +DL + + +++ E++LT TEAE + ++ ++Q ++ L +++E
Sbjct: 1245 LHKLHQDLWKTQQTRDVLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQE----- 1299
Query: 413 QQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSD---EVS 583
++ E +Q++ LE+ + E M L ++L+ A L +A G+ +
Sbjct: 1300 EKSKWEGKQNS---------LESELMELHETMASLQSRLRRAELQRMEAQGERELLQAAK 1350
Query: 584 RKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLK 700
L + L+ A ++ + LE +L+ ++LK
Sbjct: 1351 ENLTAQVEHLQAAVVEARAQASAAGILEEDLRTARSALK 1389
Score = 37.5 bits (83), Expect = 0.049
Identities = 42/208 (20%), Positives = 94/208 (45%), Gaps = 3/208 (1%)
Frame = +2
Query: 113 AMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANK 292
+ +LE+ K ++Q L+ + + E REL++ Q +DL + + +
Sbjct: 945 SQQLERLRQDMKVQKLKEQETTGILQTQ-LQEAQRELKEAARQHRDDLAALQEESSSLLQ 1003
Query: 293 DLEEKEKQLTATEAEVAALNRKVQQIEEDLEKS--EERSGTAQQKLLEAQQSADENNRMC 466
D + +KQ+ ++++ A + + +E+++++ E + QK LE ++++ + M
Sbjct: 1004 DKMDLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRIQKELEREKASLTLSLME 1063
Query: 467 KVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGD 646
K Q+ + + Q +L R ++A G+ E+S ++ + E++ E + +
Sbjct: 1064 KEQRLLVLQEADSIRQ--QELSALRQDMQEAQGEQKELSAQMELLRQEVKEKEADFLAQE 1121
Query: 647 AK-ISXLEXELKVVGNSLKSLEVSEXKA 727
A+ + LE SL E KA
Sbjct: 1122 AQLLEELEASHITEQQLRASLWAQEAKA 1149
Score = 34.7 bits (76), Expect = 0.35
Identities = 40/208 (19%), Positives = 95/208 (45%), Gaps = 4/208 (1%)
Frame = +2
Query: 119 KLEKDNAMDKADTCEQQARDANLRAEKVN--EEVRELQKKLAQVEEDLILNKNKLEQANK 292
+L++ + D Q ++L +K++ ++V +L+ +L ++ L + ++++ +
Sbjct: 979 ELKEAARQHRDDLAALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLR 1038
Query: 293 DLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKV 472
+ +E + E E A+L + + E+ L +E QQ+L +Q E
Sbjct: 1039 ETQEYNRIQKELEREKASLTLSLMEKEQRLLVLQEADSIRQQELSALRQDMQE------- 1091
Query: 473 LENRAQQDEERMDQLTNQL--KEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGD 646
+ ++ +M+ L ++ KEA LA++A +E+ E +L + + + +
Sbjct: 1092 AQGEQKELSAQMELLRQEVKEKEADFLAQEAQ-LLEELEAS-HITEQQLRAS---LWAQE 1146
Query: 647 AKISXLEXELKVVGNSLKSLEVSEXKAN 730
AK + L+ L+ + L++L + N
Sbjct: 1147 AKAAQLQLRLRSTESQLEALAAEQQPGN 1174
Score = 33.5 bits (73), Expect = 0.80
Identities = 21/121 (17%), Positives = 60/121 (49%)
Frame = +2
Query: 89 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 268
+ + +K A +++ +N + + Q+ + +R +++ VRELQ LAQ E++++ +
Sbjct: 2058 EQLLEKSLAQRVQ-ENMIQEKQNLGQEREEEEIRG--LHQSVRELQLTLAQKEQEILELR 2114
Query: 269 NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSAD 448
++ N + + + E + L+ +++ +LE+ + + + +E ++ A
Sbjct: 2115 ETQQRNNLEALPHSHKTSPMEEQSLKLDSLEPRLQRELERLQAALRQTEAREIEWREKAQ 2174
Query: 449 E 451
+
Sbjct: 2175 D 2175
Score = 30.7 bits (66), Expect = 5.6
Identities = 25/97 (25%), Positives = 50/97 (51%)
Frame = +2
Query: 161 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 340
E Q RD +++++ E++ ELQ++ + +DL +L + ++ E Q T +
Sbjct: 1624 ELQERDQEVKSQR--EQIEELQRQKEHLTQDLERRDQELMLQKERIQVLEDQRT---RQT 1678
Query: 341 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADE 451
L ++QI+ L + R T Q++L+ Q+ A+E
Sbjct: 1679 KILEEDLEQIKLSL-RERGRELTTQRQLM--QERAEE 1712
Score = 30.3 bits (65), Expect = 7.4
Identities = 41/174 (23%), Positives = 69/174 (39%), Gaps = 16/174 (9%)
Frame = +2
Query: 206 EEVRELQK-KLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDL 382
E RE Q+ L + DL +L+ + + + E T E+ +++V+ E +
Sbjct: 1580 EGQRETQRVALTHLTLDLEERSQELQAQSSQIHDLESHSTVLARELQERDQEVKSQREQI 1639
Query: 383 EKSEERSGTAQQKLLEAQQS-----------ADENNRMCKVLENRAQQDE----ERMDQL 517
E+ + + Q L Q D+ R K+LE +Q + ER +L
Sbjct: 1640 EELQRQKEHLTQDLERRDQELMLQKERIQVLEDQRTRQTKILEEDLEQIKLSLRERGREL 1699
Query: 518 TNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELK 679
T Q + + AE+ G S L ++ L E V+ I L+ ELK
Sbjct: 1700 TTQRQLMQERAEEGKGPSKAQRGSLEHMKLILRDKEKEVECQQEHIHELQ-ELK 1752
>AF022655-1|AAC06349.1| 2442|Homo sapiens cep250 centrosome associated
protein protein.
Length = 2442
Score = 52.8 bits (121), Expect = 1e-06
Identities = 46/186 (24%), Positives = 89/186 (47%), Gaps = 7/186 (3%)
Frame = +2
Query: 173 RDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALN 352
RD E E + ELQ+ Q+E+ +L+ ++ + E L+ E E+ L
Sbjct: 1732 RDKEKEVECQQEHIHELQELKDQLEQ-------QLQGLHRKVGETSLLLSQREQEIVVLQ 1784
Query: 353 RKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQ---DEERM----D 511
QQ++E E+ E + + Q +L EAQ++ + ++ + L+ QQ EER+ D
Sbjct: 1785 ---QQLQEAREQGELKEQSLQSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVKEKAD 1841
Query: 512 QLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGN 691
L L++A + ++ G+ + + +E+EL V RV++ + + L E +
Sbjct: 1842 ALQGALEQAHMTLKERHGELQDHKEQARRLEEELAVEGRRVQALEEVLGDLRAESREQEK 1901
Query: 692 SLKSLE 709
+L +L+
Sbjct: 1902 ALLALQ 1907
Score = 44.8 bits (101), Expect = 3e-04
Identities = 42/213 (19%), Positives = 94/213 (44%)
Frame = +2
Query: 71 QKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEE 250
Q+ ++A++++ Q + +++ +KAD + A++ ++ + E+++ +++ ++EE
Sbjct: 1814 QRDQELEALQQEQQQAQGQEERVKEKADALQGALEQAHMTLKERHGELQDHKEQARRLEE 1873
Query: 251 DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLE 430
+L + +++ + L + + E + AL QQ E ++ E + Q L+
Sbjct: 1874 ELAVEGRRVQALEEVLGDLRAESREQEKALLALQ---QQCAEQAQEHEVETRALQDSWLQ 1930
Query: 431 AQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDE 610
AQ E ++ + L RA+ R +Q + AR AE + L E
Sbjct: 1931 AQAVLKERDQELEAL--RAESQSSR-----HQEEAARARAEALQEALGKAHAALQGKEQH 1983
Query: 611 LEVAEDRVKSGDAKISXLEXELKVVGNSLKSLE 709
L + +S +A + L+ L + LE
Sbjct: 1984 LLEQAELSRSLEASTATLQASLDACQAHSRQLE 2016
Score = 42.7 bits (96), Expect = 0.001
Identities = 48/226 (21%), Positives = 92/226 (40%), Gaps = 7/226 (3%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
Q + A + +QA +E A E+ R A + NEEV +++ ++
Sbjct: 1347 QAAKENLTAQVEHLQAAVVEARAQASAAGILEEDLRTARSALKLKNEEVESERERAQALQ 1406
Query: 248 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 427
E L + + ++L + L E EV L ++Q++E+ E + L
Sbjct: 1407 EQGELKVAQGKALQENLALLTQTLAEREEEVETLRGQIQELEKQREMQKAALELLSLDLK 1466
Query: 428 EAQQSAD-------ENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSR 586
+ Q D E + VLE+ +ER +LT Q ++ R +D + + + +
Sbjct: 1467 KRNQEVDLQQEQIQELEKCRSVLEHLPMAVQEREQKLTVQREQIREPEKDRETQRNVLEH 1526
Query: 587 KLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXK 724
+L ELE + ++S ++ L+ +L + LE + K
Sbjct: 1527 QLL----ELEKKDQMIESQRGQVQDLKKQLVTLECLALELEENHHK 1568
Score = 41.9 bits (94), Expect = 0.002
Identities = 53/214 (24%), Positives = 93/214 (43%), Gaps = 20/214 (9%)
Frame = +2
Query: 71 QKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAE--KVNEEVRELQKKLAQV 244
+ A +D + + + L + N +A + + A L+A+ + EE E+QKKL++
Sbjct: 640 RNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSES 699
Query: 245 EEDLILNKNKLEQANKDLEEKEKQLT-------ATEAEVAALNRKVQQIEEDLEK-SEER 400
+LEQ +++ + +E+ L A E AAL ++Q +E D + + +
Sbjct: 700 RHQQEAATTQLEQLHQEAKRQEEVLARAVQEKEALVREKAALEVRLQAVERDRQDLAAQL 759
Query: 401 SGTAQQK------LLEAQQS---ADENNRMCKVLENRAQQDEERMDQLTNQLK-EARLLA 550
G + K L EAQQ DE +V Q +E + LK E
Sbjct: 760 QGLSSAKELLESSLFEAQQQNSVIDEPQGQLEVQIQTVTQAKEVIQGEVRCLKLELDTER 819
Query: 551 EDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAK 652
A+ + D +R+LA E E + A ++ K+ K
Sbjct: 820 SQAEQERDAAARQLAQAEQEGKTALEQQKAAHEK 853
Score = 40.3 bits (90), Expect = 0.007
Identities = 57/243 (23%), Positives = 108/243 (44%), Gaps = 29/243 (11%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQAR--DANLRAEKVN--EEVREL--QK 229
Q++ T D ++++ Q + L+K+ D +Q + + +L K++ E REL Q+
Sbjct: 1645 QKEHLTQD-LERRDQELMLQKERIQVLEDQRTRQTKILEEDLEQIKLSLRERGRELTTQR 1703
Query: 230 KLAQ--VEEDLILNK---NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSE 394
+L Q EE +K LE L +KEK++ + + L Q+E+ L+
Sbjct: 1704 QLMQERAEEGKGPSKAQRGSLEHMKLILRDKEKEVECQQEHIHELQELKDQLEQQLQGLH 1763
Query: 395 ERSGTA-------QQKLLEAQQSADENNRMCKVLEN--RAQQDEER--MDQLTNQLKEAR 541
+ G +Q+++ QQ E ++ E ++Q DE + + Q +L+ +
Sbjct: 1764 RKVGETSLLLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQRALAQRDQELEALQ 1823
Query: 542 LLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKIS-------XLEXELKVVGNSLK 700
+ A G+ + V K ++ LE A +K ++ LE EL V G ++
Sbjct: 1824 QEQQQAQGQEERVKEKADALQGALEQAHMTLKERHGELQDHKEQARRLEEELAVEGRRVQ 1883
Query: 701 SLE 709
+LE
Sbjct: 1884 ALE 1886
Score = 38.3 bits (85), Expect = 0.028
Identities = 33/159 (20%), Positives = 75/159 (47%), Gaps = 3/159 (1%)
Frame = +2
Query: 233 LAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTA 412
L ++ +DL + + +++ E++LT TEAE + ++ ++Q ++ L +++E
Sbjct: 1245 LLKLHQDLWKTQQTRDVLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQE----- 1299
Query: 413 QQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSD---EVS 583
++ E +Q++ LE+ + E M L ++L+ A L +A G+ +
Sbjct: 1300 EKSKWEGKQNS---------LESELMELHETMASLQSRLRRAELQRMEAQGERELLQAAK 1350
Query: 584 RKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLK 700
L + L+ A ++ + LE +L+ ++LK
Sbjct: 1351 ENLTAQVEHLQAAVVEARAQASAAGILEEDLRTARSALK 1389
Score = 37.5 bits (83), Expect = 0.049
Identities = 42/208 (20%), Positives = 94/208 (45%), Gaps = 3/208 (1%)
Frame = +2
Query: 113 AMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANK 292
+ +LE+ K ++Q L+ + + E REL++ Q +DL + + +
Sbjct: 945 SQQLERLRQDMKVQKLKEQETTGILQTQ-LQEAQRELKEAARQHRDDLAALQEESSSLLQ 1003
Query: 293 DLEEKEKQLTATEAEVAALNRKVQQIEEDLEKS--EERSGTAQQKLLEAQQSADENNRMC 466
D + +KQ+ ++++ A + + +E+++++ E + QK LE ++++ + M
Sbjct: 1004 DKMDLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRIQKELEREKASLTLSLME 1063
Query: 467 KVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGD 646
K Q+ + + Q +L R ++A G+ E+S ++ + E++ E + +
Sbjct: 1064 KEQRLLVLQEADSIRQ--QELSALRQDMQEAQGEQKELSAQMELLRQEVKEKEADFLAQE 1121
Query: 647 AK-ISXLEXELKVVGNSLKSLEVSEXKA 727
A+ + LE SL E KA
Sbjct: 1122 AQLLEELEASHITEQQLRASLWAQEAKA 1149
Score = 33.9 bits (74), Expect = 0.60
Identities = 40/208 (19%), Positives = 94/208 (45%), Gaps = 4/208 (1%)
Frame = +2
Query: 119 KLEKDNAMDKADTCEQQARDANLRAEKVN--EEVRELQKKLAQVEEDLILNKNKLEQANK 292
+L++ + D Q ++L +K++ ++V +L+ +L ++ L + ++++ +
Sbjct: 979 ELKEAARQHRDDLAALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLR 1038
Query: 293 DLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKV 472
+ +E + E E A+L + + E+ L +E QQ+L +Q E
Sbjct: 1039 ETQEYNRIQKELEREKASLTLSLMEKEQRLLVLQEADSIRQQELSALRQDMQE------- 1091
Query: 473 LENRAQQDEERMDQLTNQL--KEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGD 646
+ ++ +M+ L ++ KEA LA++A +E+ E +L + + + +
Sbjct: 1092 AQGEQKELSAQMELLRQEVKEKEADFLAQEAQ-LLEELEAS-HITEQQLRAS---LWAQE 1146
Query: 647 AKISXLEXELKVVGNSLKSLEVSEXKAN 730
AK + L L+ + L++L + N
Sbjct: 1147 AKAAQLHLRLRSTESQLEALAAEQQPGN 1174
Score = 33.1 bits (72), Expect = 1.1
Identities = 28/135 (20%), Positives = 62/135 (45%), Gaps = 7/135 (5%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMK--LEKDNAMDKADTCEQQARDANLRAEK-----VNEEVRELQ 226
QQ A D + Q + LEK A + Q+ ++ L E+ +++ VRELQ
Sbjct: 2041 QQALAQRDEELRHQQEREQLLEKSLAQRVQENMIQEKQNLGLEREEEEIRGLHQSVRELQ 2100
Query: 227 KKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSG 406
LAQ E++++ + ++ N + + + E + L+ +++ +LE+ +
Sbjct: 2101 LTLAQKEQEILELRETQQRNNLEALPHSHKTSPMEEQSLKLDSLEPRLQRELERLQAALR 2160
Query: 407 TAQQKLLEAQQSADE 451
+ + +E ++ A +
Sbjct: 2161 QTEAREIEWREKAQD 2175
Score = 30.7 bits (66), Expect = 5.6
Identities = 25/97 (25%), Positives = 50/97 (51%)
Frame = +2
Query: 161 EQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEV 340
E Q RD +++++ E++ ELQ++ + +DL +L + ++ E Q T +
Sbjct: 1624 ELQERDQEVKSQR--EQIEELQRQKEHLTQDLERRDQELMLQKERIQVLEDQRT---RQT 1678
Query: 341 AALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADE 451
L ++QI+ L + R T Q++L+ Q+ A+E
Sbjct: 1679 KILEEDLEQIKLSL-RERGRELTTQRQLM--QERAEE 1712
Score = 30.3 bits (65), Expect = 7.4
Identities = 41/174 (23%), Positives = 69/174 (39%), Gaps = 16/174 (9%)
Frame = +2
Query: 206 EEVRELQK-KLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDL 382
E RE Q+ L + DL +L+ + + + E T E+ +++V+ E +
Sbjct: 1580 EGQRETQRVALTHLTLDLEERSQELQAQSSQIHDLESHSTVLARELQERDQEVKSQREQI 1639
Query: 383 EKSEERSGTAQQKLLEAQQS-----------ADENNRMCKVLENRAQQDE----ERMDQL 517
E+ + + Q L Q D+ R K+LE +Q + ER +L
Sbjct: 1640 EELQRQKEHLTQDLERRDQELMLQKERIQVLEDQRTRQTKILEEDLEQIKLSLRERGREL 1699
Query: 518 TNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELK 679
T Q + + AE+ G S L ++ L E V+ I L+ ELK
Sbjct: 1700 TTQRQLMQERAEEGKGPSKAQRGSLEHMKLILRDKEKEVECQQEHIHELQ-ELK 1752
>AB201172-1|BAE44387.1| 1870|Homo sapiens girdin protein.
Length = 1870
Score = 52.8 bits (121), Expect = 1e-06
Identities = 55/217 (25%), Positives = 103/217 (47%), Gaps = 18/217 (8%)
Frame = +2
Query: 83 TMDAIKK-KMQAMKLEKDNAMDKADTCE-----QQARDANLRAEKVNEEVRELQKKLAQV 244
T+D+ K Q LEK+N+ + E + + A+++ ++ E +EL+ + Q+
Sbjct: 678 TLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQL 737
Query: 245 EEDLILNK------NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSG 406
++ L L K +LE + + L+ + ++L T + N+K+QQ+E +L+ E +
Sbjct: 738 KKGLELLKASFKKTERLEVSYQGLDIENQRLQKT---LENSNKKIQQLESELQDLEMENQ 794
Query: 407 TAQQKLLEAQQSA---DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDE 577
T Q+ L E + S+ ++ + K LE Q E+ QL + K R AE D +E
Sbjct: 795 TLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEE 854
Query: 578 VSRKLAFVEDELEVAEDRV---KSGDAKISXLEXELK 679
+ K+ +E E + + K ++ LE E K
Sbjct: 855 NNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENK 891
Score = 44.4 bits (100), Expect = 4e-04
Identities = 35/215 (16%), Positives = 102/215 (47%), Gaps = 3/215 (1%)
Frame = +2
Query: 89 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE---EDLI 259
+ +KK ++ +K + K + E + ++ +++ + + KK+ Q+E +DL
Sbjct: 735 EQLKKGLELLKA----SFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLE 790
Query: 260 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 439
+ L++ ++L+ K+L E E +L ++ Q+E+D ++ E+ + +Q+
Sbjct: 791 MENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDT 850
Query: 440 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 619
+ +ENN V +++ + + + KE+ + ++ + ++ E+ ++ L
Sbjct: 851 TLEENN----VKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKTLVT 906
Query: 620 AEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXK 724
+ + S K + +L+ + + L+ + +++ +
Sbjct: 907 LREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKER 941
Score = 41.9 bits (94), Expect = 0.002
Identities = 46/203 (22%), Positives = 93/203 (45%), Gaps = 24/203 (11%)
Frame = +2
Query: 173 RDANLRAEKVNEEVRELQKK-------LAQVEEDLILNKNKLEQANKDLEE--------- 304
+++ +R +++ +E +EL K+ L + EDL+ K K +Q N DLE+
Sbjct: 877 KESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIG 936
Query: 305 --KEKQL---TATEAEVAALNRKVQQ-IEEDLEKSEERSGTAQQKLLEAQQSADENNRMC 466
KE+ L +T+ L K++ +++ LE EE+ + +L E+ + +
Sbjct: 937 LNKERLLHDEQSTDDRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQEL 996
Query: 467 KVLENRAQQDEERMDQLTNQLKEARLLAEDA--DGKSDEVSRKLAFVEDELEVAEDRVKS 640
K ++ + ++R D+ + ED + +S E +R+L V+D L E +
Sbjct: 997 KTVKKNYEALKQRQDEERMVQSSPPISGEDNKWERESQETTRELLKVKDRLIEVERNNAT 1056
Query: 641 GDAKISXLEXELKVVGNSLKSLE 709
A+ L+ +LK + +L+
Sbjct: 1057 LQAEKQALKTQLKQLETQNNNLQ 1079
>AB125644-1|BAF44475.1| 1843|Homo sapiens PKB/Akt-binding protein
protein.
Length = 1843
Score = 52.8 bits (121), Expect = 1e-06
Identities = 55/217 (25%), Positives = 103/217 (47%), Gaps = 18/217 (8%)
Frame = +2
Query: 83 TMDAIKK-KMQAMKLEKDNAMDKADTCE-----QQARDANLRAEKVNEEVRELQKKLAQV 244
T+D+ K Q LEK+N+ + E + + A+++ ++ E +EL+ + Q+
Sbjct: 678 TLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQL 737
Query: 245 EEDLILNK------NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSG 406
++ L L K +LE + + L+ + ++L T + N+K+QQ+E +L+ E +
Sbjct: 738 KKGLELLKASFKKTERLEVSYQGLDIENQRLQKT---LENSNKKIQQLESELQDLEMENQ 794
Query: 407 TAQQKLLEAQQSA---DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDE 577
T Q+ L E + S+ ++ + K LE Q E+ QL + K R AE D +E
Sbjct: 795 TLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEE 854
Query: 578 VSRKLAFVEDELEVAEDRV---KSGDAKISXLEXELK 679
+ K+ +E E + + K ++ LE E K
Sbjct: 855 NNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENK 891
Score = 44.4 bits (100), Expect = 4e-04
Identities = 35/215 (16%), Positives = 102/215 (47%), Gaps = 3/215 (1%)
Frame = +2
Query: 89 DAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE---EDLI 259
+ +KK ++ +K + K + E + ++ +++ + + KK+ Q+E +DL
Sbjct: 735 EQLKKGLELLKA----SFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLE 790
Query: 260 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 439
+ L++ ++L+ K+L E E +L ++ Q+E+D ++ E+ + +Q+
Sbjct: 791 MENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDT 850
Query: 440 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEV 619
+ +ENN V +++ + + + KE+ + ++ + ++ E+ ++ L
Sbjct: 851 TLEENN----VKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKTLVT 906
Query: 620 AEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXK 724
+ + S K + +L+ + + L+ + +++ +
Sbjct: 907 LREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKER 941
>BC146789-1|AAI46790.1| 1583|Homo sapiens GRIP and coiled-coil domain
containing 2 protein.
Length = 1583
Score = 52.4 bits (120), Expect = 2e-06
Identities = 37/209 (17%), Positives = 100/209 (47%), Gaps = 5/209 (2%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
++ A T++ +++ ++ EK E +DA + +N E+ + ++ + ++
Sbjct: 1014 KEHATTVNELEELQVQLQKEKKQLQKTMQELELVKKDAQ-QTTLMNMEIADYERLMKELN 1072
Query: 248 EDLILNKNKLEQANKDLE-EKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL 424
+ L NK+E ++++ +K+KQ T E E+ +L VQQ EE K ++ +++L
Sbjct: 1073 QKLTNKNNKIEDLEQEIKIQKQKQETLQE-EITSLQSSVQQYEEKNTKIKQLLVKTKKEL 1131
Query: 425 LEAQQSADENNRMCKVLENRAQQDEERMD----QLTNQLKEARLLAEDADGKSDEVSRKL 592
+++Q+ ++ + L+ + +++++ QL E + E +++ R L
Sbjct: 1132 ADSKQAETDHLILQASLKGELEASQQQVEVYKIQLAEITSEKHKIHEHLKTSAEQHQRTL 1191
Query: 593 AFVEDELEVAEDRVKSGDAKISXLEXELK 679
+ + + ++ ++ A+ + + E +
Sbjct: 1192 SAYQQRVTALQEECRAAKAEQATVTSEFE 1220
Score = 50.8 bits (116), Expect = 5e-06
Identities = 45/204 (22%), Positives = 99/204 (48%), Gaps = 4/204 (1%)
Frame = +2
Query: 104 KMQAMKLEKDNAM-DKADTCEQQARDANLR--AEKVNEEVRELQKKLAQVEEDLILNKNK 274
++Q +++++ AM DK E+ ++ ++ A VNE + ELQ +L + ++ L +
Sbjct: 985 EVQILEVQRAKAMVDKELEAEKLQKEQKIKEHATTVNE-LEELQVQLQKEKKQLQKTMQE 1043
Query: 275 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 454
LE KD + Q T E+A R ++++ + L + +Q++ +Q +
Sbjct: 1044 LELVKKDAQ----QTTLMNMEIADYERLMKELNQKLTNKNNKIEDLEQEIKIQKQKQETL 1099
Query: 455 NRMCKVLENRAQQDEERMDQLTNQL-KEARLLAEDADGKSDEVSRKLAFVEDELEVAEDR 631
L++ QQ EE+ ++ L K + LA+ ++D + + A ++ ELE ++ +
Sbjct: 1100 QEEITSLQSSVQQYEEKNTKIKQLLVKTKKELADSKQAETDHLILQ-ASLKGELEASQQQ 1158
Query: 632 VKSGDAKISXLEXELKVVGNSLKS 703
V+ +++ + E + LK+
Sbjct: 1159 VEVYKIQLAEITSEKHKIHEHLKT 1182
Score = 40.3 bits (90), Expect = 0.007
Identities = 40/203 (19%), Positives = 91/203 (44%), Gaps = 8/203 (3%)
Frame = +2
Query: 95 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKV------NEEVREL--QKKLAQVEE 250
+K + +LE N + + + Q + + EK +E ++ L QK+L
Sbjct: 763 MKNANEKTRLENQNLLIQVEEVSQTCSKSEIHNEKEKCFIKEHENLKPLLEQKELRDRRA 822
Query: 251 DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLE 430
+LIL K+ L K K L++ V L K++ +E++ ++ EE+ + ++
Sbjct: 823 ELILLKDSLA---KSPSVKNDPLSS----VKELEEKIENLEKECKEKEEKINKIKLVAVK 875
Query: 431 AQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDE 610
A++ D + + + ++ + DQL+ +++ AE E ++ ++
Sbjct: 876 AKKELDSSRKETQTVKEELESLRSEKDQLSASMRDLIQGAESYKNLLLEYEKQ----SEQ 931
Query: 611 LEVAEDRVKSGDAKISXLEXELK 679
L+V ++R + + +I L +L+
Sbjct: 932 LDVEKERANNFEHRIEDLTRQLR 954
Score = 38.7 bits (86), Expect = 0.021
Identities = 38/182 (20%), Positives = 87/182 (47%), Gaps = 15/182 (8%)
Frame = +2
Query: 116 MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN-----KLE 280
+K ++ ++ + + + RD + +E+ E+Q + ++ DL+ KN +LE
Sbjct: 714 IKCLQEESVVQCEELKSLLRDYEQEKVLLRKELEEIQSEKEALQSDLLEMKNANEKTRLE 773
Query: 281 QANKDLEEKEKQLTATEAEVAALNRKV-----QQIEEDLEKSEERSGTAQQKLLE---AQ 436
N ++ +E T +++E+ K + ++ LE+ E R A+ LL+ A+
Sbjct: 774 NQNLLIQVEEVSQTCSKSEIHNEKEKCFIKEHENLKPLLEQKELRDRRAELILLKDSLAK 833
Query: 437 QSADENNRMCKV--LENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDE 610
+ +N+ + V LE + + E+ + ++ + +L+A A + D ++ V++E
Sbjct: 834 SPSVKNDPLSSVKELEEKIENLEKECKEKEEKINKIKLVAVKAKKELDSSRKETQTVKEE 893
Query: 611 LE 616
LE
Sbjct: 894 LE 895
Score = 34.3 bits (75), Expect = 0.46
Identities = 53/215 (24%), Positives = 96/215 (44%), Gaps = 17/215 (7%)
Frame = +2
Query: 86 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 265
MD KK + E+ ++ EQ + + +KVNE L++ L + ++ N
Sbjct: 509 MDNFHKKCER---EERLILELGKKVEQTIQYNSELEQKVNELTGGLEETLKEKDQ----N 561
Query: 266 KNKLEQANKDLEEKEKQLTATEAEVAAL---NRKV----QQIEEDLEK--SEERSGTAQQ 418
KLE+ ++ + AEV +L N K+ +Q+ DLE S++ ++
Sbjct: 562 DQKLEKLMVQMKVLSEDKEVLSAEVKSLYEENNKLSSEKKQLSRDLEVFLSQKEDVILKE 621
Query: 419 KLLEAQQS----ADENNRMCKVLENRAQQDEERMDQLTNQLKE-ARLLAEDADGKSDEVS 583
+ + ++ +E + + K+LEN Q QL LKE ++ED++ K D V+
Sbjct: 622 HITQLEKKLQLMVEEQDNLNKLLENEQVQKLFVKTQLYGFLKEMGSEVSEDSEEK-DVVN 680
Query: 584 RKLAFVEDELEVAEDRVK---SGDAKISXLEXELK 679
A E ++ E++ D K+ LE E+K
Sbjct: 681 VLQAVGESLAKINEEKCNLAFQRDEKVLELEKEIK 715
>BC029425-1|AAH29425.1| 272|Homo sapiens Unknown (protein for
IMAGE:4616553) protein.
Length = 272
Score = 52.4 bits (120), Expect = 2e-06
Identities = 59/230 (25%), Positives = 107/230 (46%), Gaps = 17/230 (7%)
Frame = +2
Query: 74 KAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLA----Q 241
KA T + + + + +KLE D KA Q+ + N + R+L+ KL +
Sbjct: 35 KAITSKSKEDRQKLLKLEVDFE-HKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLTQR 93
Query: 242 VEEDLILNKNKLEQANKDLEEKEKQLTATE-------AEVAALNRKVQQIE---EDLEKS 391
+EE NKN L++A ++L+E ++ E AEV L ++V ++E E++ K+
Sbjct: 94 IEELEETNKN-LQKAEEELQELRDKIAKGECGNSSLMAEVENLRKRVLEMEGKDEEITKT 152
Query: 392 EERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKS 571
E + ++KL E + + E + L+ R + E+ + + E L + + K
Sbjct: 153 ESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSKSKSECTQLHLNLE-KE 211
Query: 572 DEVSRKLAFVEDELEVAEDRVKS---GDAKISXLEXELKVVGNSLKSLEV 712
+++ L +ELEV + RVK ++++ E LK LKS V
Sbjct: 212 KNLTKDLL---NELEVVKSRVKELECSESRLEKAELSLKDDLTKLKSFTV 258
Score = 41.5 bits (93), Expect = 0.003
Identities = 41/202 (20%), Positives = 90/202 (44%), Gaps = 15/202 (7%)
Frame = +2
Query: 146 KADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEK----EK 313
K Q+ R+ + + + + +E ++KL ++E D ++ Q ++++ K E
Sbjct: 19 KVQDLTQKLREEEEKLKAITSKSKEDRQKLLKLEVDFEHKASRFSQEHEEMNAKLANQES 78
Query: 314 QLTATEAEVAALNRKVQQIEE---DLEKSEERSGTAQQKLLEAQ-----QSADENNRMCK 469
++ L ++++++EE +L+K+EE + K+ + + A+ N +
Sbjct: 79 HNRQLRLKLVGLTQRIEELEETNKNLQKAEEELQELRDKIAKGECGNSSLMAEVENLRKR 138
Query: 470 VLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVS---RKLAFVEDELEVAEDRVKS 640
VLE + +E + + +Q +E R ++ + S E+ KL ELE E+
Sbjct: 139 VLEMEGK--DEEITKTESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSK 196
Query: 641 GDAKISXLEXELKVVGNSLKSL 706
++ + L L+ N K L
Sbjct: 197 SKSECTQLHLNLEKEKNLTKDL 218
>AL832639-1|CAD89954.1| 1331|Homo sapiens hypothetical protein
protein.
Length = 1331
Score = 52.4 bits (120), Expect = 2e-06
Identities = 43/191 (22%), Positives = 88/191 (46%), Gaps = 4/191 (2%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
+++ + A KKKMQ E + +++ ++ Q+ L+ EKV E + KKL +
Sbjct: 792 EERCQHLQAEKKKMQQNIQELEEQLEEEESARQK-----LQLEKVTTEAK--LKKLEEEL 844
Query: 248 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKV----QQIEEDLEKSEERSGTAQ 415
+DL+++ + Q+ +LE+K+K+ AE ++ K + E + + E ++ +
Sbjct: 845 DDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAGERDRAEAEAREKETKALSLA 904
Query: 416 QKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLA 595
+ L EA + E R+ K + D + + E + + +E+ +L
Sbjct: 905 RALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLE 964
Query: 596 FVEDELEVAED 628
+E EL+ ED
Sbjct: 965 ELEGELQATED 975
Score = 51.2 bits (117), Expect = 4e-06
Identities = 52/221 (23%), Positives = 103/221 (46%), Gaps = 23/221 (10%)
Frame = +2
Query: 92 AIKKKMQAMK-LEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNK 268
A K + +A+K L K A K C ++ D E++ + +E +KKL +E ++I +
Sbjct: 1051 ANKNRDEAIKQLRKLQAQMK--DCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQ 1108
Query: 269 NKL---EQANKDLEEKEKQLTATEA-----------EVAALNRKVQQIEEDLEKSEERSG 406
+L E+A + +++ +L A E L ++ Q+EE+LE+ + +
Sbjct: 1109 EELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTE 1168
Query: 407 TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADG--KS--- 571
+L +A D+ N + + AQ++E QL Q KE ++ ++ +G KS
Sbjct: 1169 LINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYK 1228
Query: 572 ---DEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVV 685
+ K+A +E++L+ ++ ++ E +LK V
Sbjct: 1229 ASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDV 1269
Score = 45.2 bits (102), Expect = 2e-04
Identities = 41/195 (21%), Positives = 86/195 (44%), Gaps = 7/195 (3%)
Frame = +2
Query: 146 KADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTA 325
K E+ D R E+ E + LQ + ++++++ + +LE+ ++ + +
Sbjct: 773 KKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVT 832
Query: 326 TEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ-SADENNRMCKVLENRAQQDEE 502
TEA++ L ++ + DL+ + + ++K + Q A+E K R + + E
Sbjct: 833 TEAKLKKLEEELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAGERDRAEAE 892
Query: 503 RMDQLTNQLKEARLLAEDADGKSDEVSRKLAF---VEDELEVAEDRVKSG---DAKISXL 664
++ T L AR L E + K++ F +ED + +D KS + L
Sbjct: 893 AREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRAL 952
Query: 665 EXELKVVGNSLKSLE 709
E +++ + L+ LE
Sbjct: 953 EQQVEEMKTQLEELE 967
Score = 43.2 bits (97), Expect = 0.001
Identities = 49/237 (20%), Positives = 99/237 (41%), Gaps = 17/237 (7%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEK--DNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQ 241
++ A +A +K+ +A+ L + + AM++ E+ + E + ++ K + +
Sbjct: 885 ERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHE 944
Query: 242 VEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQ----QIEEDLEKSEERSGT 409
+E+ + ++E+ LEE E +L ATE L +Q Q E DL+ +E+S
Sbjct: 945 LEKSKRALEQQVEEMKTQLEELEGELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEE 1004
Query: 410 AQQKL------LEAQQSADENNRMC-----KVLENRAQQDEERMDQLTNQLKEARLLAED 556
+++L +EA+ + R K LE + E +D EA
Sbjct: 1005 KKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRK 1064
Query: 557 ADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXKA 727
+ + R+L E + K + K+ +E E+ + L + E ++ +A
Sbjct: 1065 LQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQA 1121
Score = 43.2 bits (97), Expect = 0.001
Identities = 46/219 (21%), Positives = 100/219 (45%), Gaps = 18/219 (8%)
Frame = +2
Query: 80 ATMDA---IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNE---EVRELQKKLA- 238
AT DA ++ +QAMK + + + D ++ + +R + E E Q+ +A
Sbjct: 972 ATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAV 1031
Query: 239 ----QVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEK--SEER 400
++E DL + ++ ANK+ +E KQL +A++ R++ E+ ++ +
Sbjct: 1032 AARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAK 1091
Query: 401 SGTAQQKLLEAQQ-SADENNRMCKVLENRAQQD-EERMDQLTNQLKEARLLAED---ADG 565
+ K +EA+ E + + +AQQ+ +E D++ N + L E+ +
Sbjct: 1092 ENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEA 1151
Query: 566 KSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKV 682
+ ++ +L + E+ DR+K + +I + +L +
Sbjct: 1152 RIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNL 1190
>AL589649-3|CAH71820.1| 1213|Homo sapiens filamin A interacting
protein 1 protein.
Length = 1213
Score = 52.4 bits (120), Expect = 2e-06
Identities = 59/230 (25%), Positives = 107/230 (46%), Gaps = 17/230 (7%)
Frame = +2
Query: 74 KAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLA----Q 241
KA T + + + + +KLE D KA Q+ + N + R+L+ KL +
Sbjct: 283 KAITSKSKEDRQKLLKLEVDFE-HKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLTQR 341
Query: 242 VEEDLILNKNKLEQANKDLEEKEKQLTATE-------AEVAALNRKVQQIE---EDLEKS 391
+EE NKN L++A ++L+E ++ E AEV L ++V ++E E++ K+
Sbjct: 342 IEELEETNKN-LQKAEEELQELRDKIAKGECGNSSLMAEVENLRKRVLEMEGKDEEITKT 400
Query: 392 EERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKS 571
E + ++KL E + + E + L+ R + E+ + + E L + + K
Sbjct: 401 ESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSKSKSECTQLHLNLE-KE 459
Query: 572 DEVSRKLAFVEDELEVAEDRVKS---GDAKISXLEXELKVVGNSLKSLEV 712
+++ L +ELEV + RVK ++++ E LK LKS V
Sbjct: 460 KNLTKDLL---NELEVVKSRVKELECSESRLEKAELSLKDDLTKLKSFTV 506
Score = 44.4 bits (100), Expect = 4e-04
Identities = 42/186 (22%), Positives = 93/186 (50%), Gaps = 7/186 (3%)
Frame = +2
Query: 80 ATMDAIKKKMQAMKLEKDNAMDKADT-CEQ---QARDANLRAEKVNEEVRELQKKLAQVE 247
A ++ ++K++ M+ KD + K ++ C + + ++ ++++ EV +LQK+++++E
Sbjct: 378 AEVENLRKRVLEME-GKDEEITKTESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELE 436
Query: 248 E-DLILNKNKLEQANKDLE-EKEKQLTATEA-EVAALNRKVQQIEEDLEKSEERSGTAQQ 418
+ + +K+K E L EKEK LT E+ + +V+++E + E+ + +
Sbjct: 437 KLEEAFSKSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKAELSLKD 496
Query: 419 KLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAF 598
L + + K + + +Q+E ++D L K + D K E S+KL
Sbjct: 497 DLTKLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLK 556
Query: 599 VEDELE 616
++ E+E
Sbjct: 557 LKSEME 562
Score = 41.5 bits (93), Expect = 0.003
Identities = 41/202 (20%), Positives = 90/202 (44%), Gaps = 15/202 (7%)
Frame = +2
Query: 146 KADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEK----EK 313
K Q+ R+ + + + + +E ++KL ++E D ++ Q ++++ K E
Sbjct: 267 KVQDLTQKLREEEEKLKAITSKSKEDRQKLLKLEVDFEHKASRFSQEHEEMNAKLANQES 326
Query: 314 QLTATEAEVAALNRKVQQIEE---DLEKSEERSGTAQQKLLEAQ-----QSADENNRMCK 469
++ L ++++++EE +L+K+EE + K+ + + A+ N +
Sbjct: 327 HNRQLRLKLVGLTQRIEELEETNKNLQKAEEELQELRDKIAKGECGNSSLMAEVENLRKR 386
Query: 470 VLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVS---RKLAFVEDELEVAEDRVKS 640
VLE + +E + + +Q +E R ++ + S E+ KL ELE E+
Sbjct: 387 VLEMEGK--DEEITKTESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSK 444
Query: 641 GDAKISXLEXELKVVGNSLKSL 706
++ + L L+ N K L
Sbjct: 445 SKSECTQLHLNLEKEKNLTKDL 466
>AL589649-1|CAH71818.1| 1114|Homo sapiens filamin A interacting
protein 1 protein.
Length = 1114
Score = 52.4 bits (120), Expect = 2e-06
Identities = 59/230 (25%), Positives = 107/230 (46%), Gaps = 17/230 (7%)
Frame = +2
Query: 74 KAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLA----Q 241
KA T + + + + +KLE D KA Q+ + N + R+L+ KL +
Sbjct: 184 KAITSKSKEDRQKLLKLEVDFE-HKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLTQR 242
Query: 242 VEEDLILNKNKLEQANKDLEEKEKQLTATE-------AEVAALNRKVQQIE---EDLEKS 391
+EE NKN L++A ++L+E ++ E AEV L ++V ++E E++ K+
Sbjct: 243 IEELEETNKN-LQKAEEELQELRDKIAKGECGNSSLMAEVENLRKRVLEMEGKDEEITKT 301
Query: 392 EERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKS 571
E + ++KL E + + E + L+ R + E+ + + E L + + K
Sbjct: 302 ESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSKSKSECTQLHLNLE-KE 360
Query: 572 DEVSRKLAFVEDELEVAEDRVKS---GDAKISXLEXELKVVGNSLKSLEV 712
+++ L +ELEV + RVK ++++ E LK LKS V
Sbjct: 361 KNLTKDLL---NELEVVKSRVKELECSESRLEKAELSLKDDLTKLKSFTV 407
Score = 44.4 bits (100), Expect = 4e-04
Identities = 42/186 (22%), Positives = 93/186 (50%), Gaps = 7/186 (3%)
Frame = +2
Query: 80 ATMDAIKKKMQAMKLEKDNAMDKADT-CEQ---QARDANLRAEKVNEEVRELQKKLAQVE 247
A ++ ++K++ M+ KD + K ++ C + + ++ ++++ EV +LQK+++++E
Sbjct: 279 AEVENLRKRVLEME-GKDEEITKTESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELE 337
Query: 248 E-DLILNKNKLEQANKDLE-EKEKQLTATEA-EVAALNRKVQQIEEDLEKSEERSGTAQQ 418
+ + +K+K E L EKEK LT E+ + +V+++E + E+ + +
Sbjct: 338 KLEEAFSKSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKAELSLKD 397
Query: 419 KLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAF 598
L + + K + + +Q+E ++D L K + D K E S+KL
Sbjct: 398 DLTKLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLK 457
Query: 599 VEDELE 616
++ E+E
Sbjct: 458 LKSEME 463
Score = 41.5 bits (93), Expect = 0.003
Identities = 41/202 (20%), Positives = 90/202 (44%), Gaps = 15/202 (7%)
Frame = +2
Query: 146 KADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEK----EK 313
K Q+ R+ + + + + +E ++KL ++E D ++ Q ++++ K E
Sbjct: 168 KVQDLTQKLREEEEKLKAITSKSKEDRQKLLKLEVDFEHKASRFSQEHEEMNAKLANQES 227
Query: 314 QLTATEAEVAALNRKVQQIEE---DLEKSEERSGTAQQKLLEAQ-----QSADENNRMCK 469
++ L ++++++EE +L+K+EE + K+ + + A+ N +
Sbjct: 228 HNRQLRLKLVGLTQRIEELEETNKNLQKAEEELQELRDKIAKGECGNSSLMAEVENLRKR 287
Query: 470 VLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVS---RKLAFVEDELEVAEDRVKS 640
VLE + +E + + +Q +E R ++ + S E+ KL ELE E+
Sbjct: 288 VLEMEGK--DEEITKTESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSK 345
Query: 641 GDAKISXLEXELKVVGNSLKSL 706
++ + L L+ N K L
Sbjct: 346 SKSECTQLHLNLEKEKNLTKDL 367
>AL445465-2|CAH73615.1| 1213|Homo sapiens filamin A interacting
protein 1 protein.
Length = 1213
Score = 52.4 bits (120), Expect = 2e-06
Identities = 59/230 (25%), Positives = 107/230 (46%), Gaps = 17/230 (7%)
Frame = +2
Query: 74 KAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLA----Q 241
KA T + + + + +KLE D KA Q+ + N + R+L+ KL +
Sbjct: 283 KAITSKSKEDRQKLLKLEVDFE-HKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLTQR 341
Query: 242 VEEDLILNKNKLEQANKDLEEKEKQLTATE-------AEVAALNRKVQQIE---EDLEKS 391
+EE NKN L++A ++L+E ++ E AEV L ++V ++E E++ K+
Sbjct: 342 IEELEETNKN-LQKAEEELQELRDKIAKGECGNSSLMAEVENLRKRVLEMEGKDEEITKT 400
Query: 392 EERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKS 571
E + ++KL E + + E + L+ R + E+ + + E L + + K
Sbjct: 401 ESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSKSKSECTQLHLNLE-KE 459
Query: 572 DEVSRKLAFVEDELEVAEDRVKS---GDAKISXLEXELKVVGNSLKSLEV 712
+++ L +ELEV + RVK ++++ E LK LKS V
Sbjct: 460 KNLTKDLL---NELEVVKSRVKELECSESRLEKAELSLKDDLTKLKSFTV 506
Score = 44.4 bits (100), Expect = 4e-04
Identities = 42/186 (22%), Positives = 93/186 (50%), Gaps = 7/186 (3%)
Frame = +2
Query: 80 ATMDAIKKKMQAMKLEKDNAMDKADT-CEQ---QARDANLRAEKVNEEVRELQKKLAQVE 247
A ++ ++K++ M+ KD + K ++ C + + ++ ++++ EV +LQK+++++E
Sbjct: 378 AEVENLRKRVLEME-GKDEEITKTESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELE 436
Query: 248 E-DLILNKNKLEQANKDLE-EKEKQLTATEA-EVAALNRKVQQIEEDLEKSEERSGTAQQ 418
+ + +K+K E L EKEK LT E+ + +V+++E + E+ + +
Sbjct: 437 KLEEAFSKSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKAELSLKD 496
Query: 419 KLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAF 598
L + + K + + +Q+E ++D L K + D K E S+KL
Sbjct: 497 DLTKLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLK 556
Query: 599 VEDELE 616
++ E+E
Sbjct: 557 LKSEME 562
Score = 41.5 bits (93), Expect = 0.003
Identities = 41/202 (20%), Positives = 90/202 (44%), Gaps = 15/202 (7%)
Frame = +2
Query: 146 KADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEK----EK 313
K Q+ R+ + + + + +E ++KL ++E D ++ Q ++++ K E
Sbjct: 267 KVQDLTQKLREEEEKLKAITSKSKEDRQKLLKLEVDFEHKASRFSQEHEEMNAKLANQES 326
Query: 314 QLTATEAEVAALNRKVQQIEE---DLEKSEERSGTAQQKLLEAQ-----QSADENNRMCK 469
++ L ++++++EE +L+K+EE + K+ + + A+ N +
Sbjct: 327 HNRQLRLKLVGLTQRIEELEETNKNLQKAEEELQELRDKIAKGECGNSSLMAEVENLRKR 386
Query: 470 VLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVS---RKLAFVEDELEVAEDRVKS 640
VLE + +E + + +Q +E R ++ + S E+ KL ELE E+
Sbjct: 387 VLEMEGK--DEEITKTESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSK 444
Query: 641 GDAKISXLEXELKVVGNSLKSL 706
++ + L L+ N K L
Sbjct: 445 SKSECTQLHLNLEKEKNLTKDL 466
>AL445465-1|CAH73614.1| 1114|Homo sapiens filamin A interacting
protein 1 protein.
Length = 1114
Score = 52.4 bits (120), Expect = 2e-06
Identities = 59/230 (25%), Positives = 107/230 (46%), Gaps = 17/230 (7%)
Frame = +2
Query: 74 KAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLA----Q 241
KA T + + + + +KLE D KA Q+ + N + R+L+ KL +
Sbjct: 184 KAITSKSKEDRQKLLKLEVDFE-HKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLTQR 242
Query: 242 VEEDLILNKNKLEQANKDLEEKEKQLTATE-------AEVAALNRKVQQIE---EDLEKS 391
+EE NKN L++A ++L+E ++ E AEV L ++V ++E E++ K+
Sbjct: 243 IEELEETNKN-LQKAEEELQELRDKIAKGECGNSSLMAEVENLRKRVLEMEGKDEEITKT 301
Query: 392 EERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKS 571
E + ++KL E + + E + L+ R + E+ + + E L + + K
Sbjct: 302 ESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSKSKSECTQLHLNLE-KE 360
Query: 572 DEVSRKLAFVEDELEVAEDRVKS---GDAKISXLEXELKVVGNSLKSLEV 712
+++ L +ELEV + RVK ++++ E LK LKS V
Sbjct: 361 KNLTKDLL---NELEVVKSRVKELECSESRLEKAELSLKDDLTKLKSFTV 407
Score = 44.4 bits (100), Expect = 4e-04
Identities = 42/186 (22%), Positives = 93/186 (50%), Gaps = 7/186 (3%)
Frame = +2
Query: 80 ATMDAIKKKMQAMKLEKDNAMDKADT-CEQ---QARDANLRAEKVNEEVRELQKKLAQVE 247
A ++ ++K++ M+ KD + K ++ C + + ++ ++++ EV +LQK+++++E
Sbjct: 279 AEVENLRKRVLEME-GKDEEITKTESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELE 337
Query: 248 E-DLILNKNKLEQANKDLE-EKEKQLTATEA-EVAALNRKVQQIEEDLEKSEERSGTAQQ 418
+ + +K+K E L EKEK LT E+ + +V+++E + E+ + +
Sbjct: 338 KLEEAFSKSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKAELSLKD 397
Query: 419 KLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAF 598
L + + K + + +Q+E ++D L K + D K E S+KL
Sbjct: 398 DLTKLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLK 457
Query: 599 VEDELE 616
++ E+E
Sbjct: 458 LKSEME 463
Score = 41.5 bits (93), Expect = 0.003
Identities = 41/202 (20%), Positives = 90/202 (44%), Gaps = 15/202 (7%)
Frame = +2
Query: 146 KADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEK----EK 313
K Q+ R+ + + + + +E ++KL ++E D ++ Q ++++ K E
Sbjct: 168 KVQDLTQKLREEEEKLKAITSKSKEDRQKLLKLEVDFEHKASRFSQEHEEMNAKLANQES 227
Query: 314 QLTATEAEVAALNRKVQQIEE---DLEKSEERSGTAQQKLLEAQ-----QSADENNRMCK 469
++ L ++++++EE +L+K+EE + K+ + + A+ N +
Sbjct: 228 HNRQLRLKLVGLTQRIEELEETNKNLQKAEEELQELRDKIAKGECGNSSLMAEVENLRKR 287
Query: 470 VLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVS---RKLAFVEDELEVAEDRVKS 640
VLE + +E + + +Q +E R ++ + S E+ KL ELE E+
Sbjct: 288 VLEMEGK--DEEITKTESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSK 345
Query: 641 GDAKISXLEXELKVVGNSLKSL 706
++ + L L+ N K L
Sbjct: 346 SKSECTQLHLNLEKEKNLTKDL 367
>AK097021-1|BAC04928.1| 512|Homo sapiens protein ( Homo sapiens
cDNA FLJ39702 fis, clone SMINT2012122. ).
Length = 512
Score = 52.4 bits (120), Expect = 2e-06
Identities = 59/230 (25%), Positives = 107/230 (46%), Gaps = 17/230 (7%)
Frame = +2
Query: 74 KAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLA----Q 241
KA T + + + + +KLE D KA Q+ + N + R+L+ KL +
Sbjct: 283 KAITSKSKEDRQKLLKLEVDFE-HKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLTQR 341
Query: 242 VEEDLILNKNKLEQANKDLEEKEKQLTATE-------AEVAALNRKVQQIE---EDLEKS 391
+EE NKN L++A ++L+E ++ E AEV L ++V ++E E++ K+
Sbjct: 342 IEELEETNKN-LQKAEEELQELRDKIAKGECGNSSLMAEVENLRKRVLEMEGKDEEITKT 400
Query: 392 EERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKS 571
E + ++KL E + + E + L+ R + E+ + + E L + + K
Sbjct: 401 ESQCRELRKKLQEEEHHSKEFRLEVEKLQKRMSELEKLEEAFSKSKSECTQLHLNLE-KE 459
Query: 572 DEVSRKLAFVEDELEVAEDRVKS---GDAKISXLEXELKVVGNSLKSLEV 712
+++ L +ELEV + RVK ++++ E LK LKS V
Sbjct: 460 KNLTKDLL---NELEVVKSRVKELECSESRLEKAELSLKDDLTKLKSFTV 506
Score = 40.7 bits (91), Expect = 0.005
Identities = 41/202 (20%), Positives = 89/202 (44%), Gaps = 15/202 (7%)
Frame = +2
Query: 146 KADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEK----EK 313
K Q+ R+ + + + + +E ++KL ++E D ++ Q ++++ K E
Sbjct: 267 KVQDLTQKLREEEEKLKAITSKSKEDRQKLLKLEVDFEHKASRFSQEHEEMNAKLANQES 326
Query: 314 QLTATEAEVAALNRKVQQIEE---DLEKSEERSGTAQQKLLEAQ-----QSADENNRMCK 469
++ L ++++++EE +L+K+EE + K+ + + A+ N +
Sbjct: 327 HNRQLRLKLVGLTQRIEELEETNKNLQKAEEELQELRDKIAKGECGNSSLMAEVENLRKR 386
Query: 470 VLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVS---RKLAFVEDELEVAEDRVKS 640
VLE + +E + + +Q +E R ++ + S E KL ELE E+
Sbjct: 387 VLEMEGK--DEEITKTESQCRELRKKLQEEEHHSKEFRLEVEKLQKRMSELEKLEEAFSK 444
Query: 641 GDAKISXLEXELKVVGNSLKSL 706
++ + L L+ N K L
Sbjct: 445 SKSECTQLHLNLEKEKNLTKDL 466
>AK027705-1|BAB55310.1| 965|Homo sapiens protein ( Homo sapiens
cDNA FLJ14799 fis, clone NT2RP4001351, weakly similar to
Human ovarian cancer downregulated myosin heavy chain
homolog ).
Length = 965
Score = 52.4 bits (120), Expect = 2e-06
Identities = 59/230 (25%), Positives = 107/230 (46%), Gaps = 17/230 (7%)
Frame = +2
Query: 74 KAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLA----Q 241
KA T + + + + +KLE D KA Q+ + N + R+L+ KL +
Sbjct: 35 KAITSKSKEDRQKLLKLEVDFE-HKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLTQR 93
Query: 242 VEEDLILNKNKLEQANKDLEEKEKQLTATE-------AEVAALNRKVQQIE---EDLEKS 391
+EE NKN L++A ++L+E ++ E AEV L ++V ++E E++ K+
Sbjct: 94 IEELEETNKN-LQKAEEELQELRDKIAKGECGNSSLMAEVENLRKRVLEMEGKDEEITKT 152
Query: 392 EERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKS 571
E + ++KL E + + E + L+ R + E+ + + E L + + K
Sbjct: 153 ESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSKSKSECTQLHLNLE-KE 211
Query: 572 DEVSRKLAFVEDELEVAEDRVKS---GDAKISXLEXELKVVGNSLKSLEV 712
+++ L +ELEV + RVK ++++ E LK LKS V
Sbjct: 212 KNLTKDLL---NELEVVKSRVKELECSESRLEKAELSLKDDLTKLKSFTV 258
Score = 44.4 bits (100), Expect = 4e-04
Identities = 42/186 (22%), Positives = 93/186 (50%), Gaps = 7/186 (3%)
Frame = +2
Query: 80 ATMDAIKKKMQAMKLEKDNAMDKADT-CEQ---QARDANLRAEKVNEEVRELQKKLAQVE 247
A ++ ++K++ M+ KD + K ++ C + + ++ ++++ EV +LQK+++++E
Sbjct: 130 AEVENLRKRVLEME-GKDEEITKTESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELE 188
Query: 248 E-DLILNKNKLEQANKDLE-EKEKQLTATEA-EVAALNRKVQQIEEDLEKSEERSGTAQQ 418
+ + +K+K E L EKEK LT E+ + +V+++E + E+ + +
Sbjct: 189 KLEEAFSKSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKAELSLKD 248
Query: 419 KLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAF 598
L + + K + + +Q+E ++D L K + D K E S+KL
Sbjct: 249 DLTKLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLK 308
Query: 599 VEDELE 616
++ E+E
Sbjct: 309 LKSEME 314
Score = 41.5 bits (93), Expect = 0.003
Identities = 41/202 (20%), Positives = 90/202 (44%), Gaps = 15/202 (7%)
Frame = +2
Query: 146 KADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEK----EK 313
K Q+ R+ + + + + +E ++KL ++E D ++ Q ++++ K E
Sbjct: 19 KVQDLTQKLREEEEKLKAITSKSKEDRQKLLKLEVDFEHKASRFSQEHEEMNAKLANQES 78
Query: 314 QLTATEAEVAALNRKVQQIEE---DLEKSEERSGTAQQKLLEAQ-----QSADENNRMCK 469
++ L ++++++EE +L+K+EE + K+ + + A+ N +
Sbjct: 79 HNRQLRLKLVGLTQRIEELEETNKNLQKAEEELQELRDKIAKGECGNSSLMAEVENLRKR 138
Query: 470 VLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVS---RKLAFVEDELEVAEDRVKS 640
VLE + +E + + +Q +E R ++ + S E+ KL ELE E+
Sbjct: 139 VLEMEGK--DEEITKTESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSK 196
Query: 641 GDAKISXLEXELKVVGNSLKSL 706
++ + L L+ N K L
Sbjct: 197 SKSECTQLHLNLEKEKNLTKDL 218
>AB086011-1|BAC77067.1| 1213|Homo sapiens L-FILIP protein.
Length = 1213
Score = 52.4 bits (120), Expect = 2e-06
Identities = 59/230 (25%), Positives = 107/230 (46%), Gaps = 17/230 (7%)
Frame = +2
Query: 74 KAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLA----Q 241
KA T + + + + +KLE D KA Q+ + N + R+L+ KL +
Sbjct: 283 KAITSKSKEDRQKLLKLEVDFE-HKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLTQR 341
Query: 242 VEEDLILNKNKLEQANKDLEEKEKQLTATE-------AEVAALNRKVQQIE---EDLEKS 391
+EE NKN L++A ++L+E ++ E AEV L ++V ++E E++ K+
Sbjct: 342 IEELEETNKN-LQKAEEELQELRDKIAKGECGNSSLMAEVENLRKRVLEMEGKDEEITKT 400
Query: 392 EERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKS 571
E + ++KL E + + E + L+ R + E+ + + E L + + K
Sbjct: 401 ESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSKSKSECTQLHLNLE-KE 459
Query: 572 DEVSRKLAFVEDELEVAEDRVKS---GDAKISXLEXELKVVGNSLKSLEV 712
+++ L +ELEV + RVK ++++ E LK LKS V
Sbjct: 460 KNLTKDLL---NELEVVKSRVKELECSESRLEKAELSLKDDLTKLKSFTV 506
Score = 44.4 bits (100), Expect = 4e-04
Identities = 42/186 (22%), Positives = 93/186 (50%), Gaps = 7/186 (3%)
Frame = +2
Query: 80 ATMDAIKKKMQAMKLEKDNAMDKADT-CEQ---QARDANLRAEKVNEEVRELQKKLAQVE 247
A ++ ++K++ M+ KD + K ++ C + + ++ ++++ EV +LQK+++++E
Sbjct: 378 AEVENLRKRVLEME-GKDEEITKTESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELE 436
Query: 248 E-DLILNKNKLEQANKDLE-EKEKQLTATEA-EVAALNRKVQQIEEDLEKSEERSGTAQQ 418
+ + +K+K E L EKEK LT E+ + +V+++E + E+ + +
Sbjct: 437 KLEEAFSKSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKAELSLKD 496
Query: 419 KLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAF 598
L + + K + + +Q+E ++D L K + D K E S+KL
Sbjct: 497 DLTKLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLK 556
Query: 599 VEDELE 616
++ E+E
Sbjct: 557 LKSEME 562
Score = 41.5 bits (93), Expect = 0.003
Identities = 41/202 (20%), Positives = 90/202 (44%), Gaps = 15/202 (7%)
Frame = +2
Query: 146 KADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEK----EK 313
K Q+ R+ + + + + +E ++KL ++E D ++ Q ++++ K E
Sbjct: 267 KVQDLTQKLREEEEKLKAITSKSKEDRQKLLKLEVDFEHKASRFSQEHEEMNAKLANQES 326
Query: 314 QLTATEAEVAALNRKVQQIEE---DLEKSEERSGTAQQKLLEAQ-----QSADENNRMCK 469
++ L ++++++EE +L+K+EE + K+ + + A+ N +
Sbjct: 327 HNRQLRLKLVGLTQRIEELEETNKNLQKAEEELQELRDKIAKGECGNSSLMAEVENLRKR 386
Query: 470 VLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVS---RKLAFVEDELEVAEDRVKS 640
VLE + +E + + +Q +E R ++ + S E+ KL ELE E+
Sbjct: 387 VLEMEGK--DEEITKTESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSK 444
Query: 641 GDAKISXLEXELKVVGNSLKSL 706
++ + L L+ N K L
Sbjct: 445 SKSECTQLHLNLEKEKNLTKDL 466
>AB033101-1|BAA86589.1| 1140|Homo sapiens KIAA1275 protein protein.
Length = 1140
Score = 52.4 bits (120), Expect = 2e-06
Identities = 59/230 (25%), Positives = 107/230 (46%), Gaps = 17/230 (7%)
Frame = +2
Query: 74 KAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLA----Q 241
KA T + + + + +KLE D KA Q+ + N + R+L+ KL +
Sbjct: 210 KAITSKSKEDRQKLLKLEVDFE-HKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLTQR 268
Query: 242 VEEDLILNKNKLEQANKDLEEKEKQLTATE-------AEVAALNRKVQQIE---EDLEKS 391
+EE NKN L++A ++L+E ++ E AEV L ++V ++E E++ K+
Sbjct: 269 IEELEETNKN-LQKAEEELQELRDKIAKGECGNSSLMAEVENLRKRVLEMEGKDEEITKT 327
Query: 392 EERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKS 571
E + ++KL E + + E + L+ R + E+ + + E L + + K
Sbjct: 328 ESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSKSKSECTQLHLNLE-KE 386
Query: 572 DEVSRKLAFVEDELEVAEDRVKS---GDAKISXLEXELKVVGNSLKSLEV 712
+++ L +ELEV + RVK ++++ E LK LKS V
Sbjct: 387 KNLTKDLL---NELEVVKSRVKELECSESRLEKAELSLKDDLTKLKSFTV 433
Score = 44.4 bits (100), Expect = 4e-04
Identities = 42/186 (22%), Positives = 93/186 (50%), Gaps = 7/186 (3%)
Frame = +2
Query: 80 ATMDAIKKKMQAMKLEKDNAMDKADT-CEQ---QARDANLRAEKVNEEVRELQKKLAQVE 247
A ++ ++K++ M+ KD + K ++ C + + ++ ++++ EV +LQK+++++E
Sbjct: 305 AEVENLRKRVLEME-GKDEEITKTESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELE 363
Query: 248 E-DLILNKNKLEQANKDLE-EKEKQLTATEA-EVAALNRKVQQIEEDLEKSEERSGTAQQ 418
+ + +K+K E L EKEK LT E+ + +V+++E + E+ + +
Sbjct: 364 KLEEAFSKSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKAELSLKD 423
Query: 419 KLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAF 598
L + + K + + +Q+E ++D L K + D K E S+KL
Sbjct: 424 DLTKLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLK 483
Query: 599 VEDELE 616
++ E+E
Sbjct: 484 LKSEME 489
Score = 41.5 bits (93), Expect = 0.003
Identities = 41/202 (20%), Positives = 90/202 (44%), Gaps = 15/202 (7%)
Frame = +2
Query: 146 KADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEK----EK 313
K Q+ R+ + + + + +E ++KL ++E D ++ Q ++++ K E
Sbjct: 194 KVQDLTQKLREEEEKLKAITSKSKEDRQKLLKLEVDFEHKASRFSQEHEEMNAKLANQES 253
Query: 314 QLTATEAEVAALNRKVQQIEE---DLEKSEERSGTAQQKLLEAQ-----QSADENNRMCK 469
++ L ++++++EE +L+K+EE + K+ + + A+ N +
Sbjct: 254 HNRQLRLKLVGLTQRIEELEETNKNLQKAEEELQELRDKIAKGECGNSSLMAEVENLRKR 313
Query: 470 VLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVS---RKLAFVEDELEVAEDRVKS 640
VLE + +E + + +Q +E R ++ + S E+ KL ELE E+
Sbjct: 314 VLEMEGK--DEEITKTESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSK 371
Query: 641 GDAKISXLEXELKVVGNSLKSL 706
++ + L L+ N K L
Sbjct: 372 SKSECTQLHLNLEKEKNLTKDL 393
>AB002334-1|BAA20794.2| 1635|Homo sapiens KIAA0336 protein.
Length = 1635
Score = 52.4 bits (120), Expect = 2e-06
Identities = 37/209 (17%), Positives = 100/209 (47%), Gaps = 5/209 (2%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
++ A T++ +++ ++ EK E +DA + +N E+ + ++ + ++
Sbjct: 1066 KEHATTVNELEELQVQLQKEKKQLQKTMQELELVKKDAQ-QTTLMNMEIADYERLMKELN 1124
Query: 248 EDLILNKNKLEQANKDLE-EKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL 424
+ L NK+E ++++ +K+KQ T E E+ +L VQQ EE K ++ +++L
Sbjct: 1125 QKLTNKNNKIEDLEQEIKIQKQKQETLQE-EITSLQSSVQQYEEKNTKIKQLLVKTKKEL 1183
Query: 425 LEAQQSADENNRMCKVLENRAQQDEERMD----QLTNQLKEARLLAEDADGKSDEVSRKL 592
+++Q+ ++ + L+ + +++++ QL E + E +++ R L
Sbjct: 1184 ADSKQAETDHLILQASLKGELEASQQQVEVYKIQLAEITSEKHKIHEHLKTSAEQHQRTL 1243
Query: 593 AFVEDELEVAEDRVKSGDAKISXLEXELK 679
+ + + ++ ++ A+ + + E +
Sbjct: 1244 SAYQQRVTALQEECRAAKAEQATVTSEFE 1272
Score = 50.8 bits (116), Expect = 5e-06
Identities = 45/204 (22%), Positives = 99/204 (48%), Gaps = 4/204 (1%)
Frame = +2
Query: 104 KMQAMKLEKDNAM-DKADTCEQQARDANLR--AEKVNEEVRELQKKLAQVEEDLILNKNK 274
++Q +++++ AM DK E+ ++ ++ A VNE + ELQ +L + ++ L +
Sbjct: 1037 EVQILEVQRAKAMVDKELEAEKLQKEQKIKEHATTVNE-LEELQVQLQKEKKQLQKTMQE 1095
Query: 275 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 454
LE KD + Q T E+A R ++++ + L + +Q++ +Q +
Sbjct: 1096 LELVKKDAQ----QTTLMNMEIADYERLMKELNQKLTNKNNKIEDLEQEIKIQKQKQETL 1151
Query: 455 NRMCKVLENRAQQDEERMDQLTNQL-KEARLLAEDADGKSDEVSRKLAFVEDELEVAEDR 631
L++ QQ EE+ ++ L K + LA+ ++D + + A ++ ELE ++ +
Sbjct: 1152 QEEITSLQSSVQQYEEKNTKIKQLLVKTKKELADSKQAETDHLILQ-ASLKGELEASQQQ 1210
Query: 632 VKSGDAKISXLEXELKVVGNSLKS 703
V+ +++ + E + LK+
Sbjct: 1211 VEVYKIQLAEITSEKHKIHEHLKT 1234
Score = 40.3 bits (90), Expect = 0.007
Identities = 40/203 (19%), Positives = 91/203 (44%), Gaps = 8/203 (3%)
Frame = +2
Query: 95 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKV------NEEVREL--QKKLAQVEE 250
+K + +LE N + + + Q + + EK +E ++ L QK+L
Sbjct: 815 MKNANEKTRLENQNLLIQVEEVSQTCSKSEIHNEKEKCFIKEHENLKPLLEQKELRDRRA 874
Query: 251 DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLE 430
+LIL K+ L K K L++ V L K++ +E++ ++ EE+ + ++
Sbjct: 875 ELILLKDSLA---KSPSVKNDPLSS----VKELEEKIENLEKECKEKEEKINKIKLVAVK 927
Query: 431 AQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDE 610
A++ D + + + ++ + DQL+ +++ AE E ++ ++
Sbjct: 928 AKKELDSSRKETQTVKEELESLRSEKDQLSASMRDLIQGAESYKNLLLEYEKQ----SEQ 983
Query: 611 LEVAEDRVKSGDAKISXLEXELK 679
L+V ++R + + +I L +L+
Sbjct: 984 LDVEKERANNFEHRIEDLTRQLR 1006
Score = 38.7 bits (86), Expect = 0.021
Identities = 38/182 (20%), Positives = 87/182 (47%), Gaps = 15/182 (8%)
Frame = +2
Query: 116 MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN-----KLE 280
+K ++ ++ + + + RD + +E+ E+Q + ++ DL+ KN +LE
Sbjct: 766 IKCLQEESVVQCEELKSLLRDYEQEKVLLRKELEEIQSEKEALQSDLLEMKNANEKTRLE 825
Query: 281 QANKDLEEKEKQLTATEAEVAALNRKV-----QQIEEDLEKSEERSGTAQQKLLE---AQ 436
N ++ +E T +++E+ K + ++ LE+ E R A+ LL+ A+
Sbjct: 826 NQNLLIQVEEVSQTCSKSEIHNEKEKCFIKEHENLKPLLEQKELRDRRAELILLKDSLAK 885
Query: 437 QSADENNRMCKV--LENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDE 610
+ +N+ + V LE + + E+ + ++ + +L+A A + D ++ V++E
Sbjct: 886 SPSVKNDPLSSVKELEEKIENLEKECKEKEEKINKIKLVAVKAKKELDSSRKETQTVKEE 945
Query: 611 LE 616
LE
Sbjct: 946 LE 947
Score = 34.3 bits (75), Expect = 0.46
Identities = 53/215 (24%), Positives = 96/215 (44%), Gaps = 17/215 (7%)
Frame = +2
Query: 86 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 265
MD KK + E+ ++ EQ + + +KVNE L++ L + ++ N
Sbjct: 561 MDNFHKKCER---EERLILELGKKVEQTIQYNSELEQKVNELTGGLEETLKEKDQ----N 613
Query: 266 KNKLEQANKDLEEKEKQLTATEAEVAAL---NRKV----QQIEEDLEK--SEERSGTAQQ 418
KLE+ ++ + AEV +L N K+ +Q+ DLE S++ ++
Sbjct: 614 DQKLEKLMVQMKVLSEDKEVLSAEVKSLYEENNKLSSEKKQLSRDLEVFLSQKEDVILKE 673
Query: 419 KLLEAQQS----ADENNRMCKVLENRAQQDEERMDQLTNQLKE-ARLLAEDADGKSDEVS 583
+ + ++ +E + + K+LEN Q QL LKE ++ED++ K D V+
Sbjct: 674 HITQLEKKLQLMVEEQDNLNKLLENEQVQKLFVKTQLYGFLKEMGSEVSEDSEEK-DVVN 732
Query: 584 RKLAFVEDELEVAEDRVK---SGDAKISXLEXELK 679
A E ++ E++ D K+ LE E+K
Sbjct: 733 VLQAVGESLAKINEEKCNLAFQRDEKVLELEKEIK 767
>BC132784-1|AAI32785.1| 1116|Homo sapiens ELKS/RAB6-interacting/CAST
family member 1 protein.
Length = 1116
Score = 52.0 bits (119), Expect = 2e-06
Identities = 52/221 (23%), Positives = 107/221 (48%), Gaps = 12/221 (5%)
Frame = +2
Query: 98 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVREL-----QKKLAQVEEDLIL 262
+KK + +K+E + KA +AR + ++++ RE+ + AQ E D +L
Sbjct: 705 QKKEECLKMESQ--LKKAHEAALEARASPEMSDRIQHLEREITRYKDESSKAQAEVDRLL 762
Query: 263 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 442
L++ + +K+K++ E +V N+KV ++ + +++S Q L EA++
Sbjct: 763 EI--LKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSA---QMLEEARRR 817
Query: 443 ADENNRMCKVLENRAQQDEERMDQLTNQLKEA-RLLAEDADGKSDEVSRKLAFVE--DEL 613
D N + L++ ++ ++R+++L L+E+ ++ AE + E S + + +EL
Sbjct: 818 EDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEEL 877
Query: 614 EVAEDRVK----SGDAKISXLEXELKVVGNSLKSLEVSEXK 724
+A ++VK S AK+S + L L +L K
Sbjct: 878 LMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRK 918
Score = 50.0 bits (114), Expect = 9e-06
Identities = 47/224 (20%), Positives = 100/224 (44%), Gaps = 3/224 (1%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
+Q+AA + ++ EK+ ++K +Q +D E+ +L+ L E
Sbjct: 514 EQRAAILQTEVDALRLRLEEKETMLNKKT---KQIQDMAEEKGTQAGEIHDLKDMLDVKE 570
Query: 248 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 427
+ + + K+E + L +KEKQ+ ++L +V+ ++ D ++ T ++ L
Sbjct: 571 RKVNVLQKKIENLQEQLRDKEKQM-------SSLKERVKSLQADTTNTDTALTTLEEALA 623
Query: 428 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 607
E +++ + ++ E R + + E+ +++ N K+ + L E ++S K A + D
Sbjct: 624 EKERTIE------RLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLD 677
Query: 608 ELEVAEDRVKSG---DAKISXLEXELKVVGNSLKSLEVSEXKAN 730
E A SG D+++ LE L+ +E KA+
Sbjct: 678 LKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAH 721
Score = 42.7 bits (96), Expect = 0.001
Identities = 25/155 (16%), Positives = 71/155 (45%)
Frame = +2
Query: 194 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIE 373
E + ++ +++ L +EE++ + K+ + ++ EE+ KQ+ + + KV+Q++
Sbjct: 385 EMKDSKISSMERGLRDLEEEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKNKVEQLK 444
Query: 374 EDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAE 553
E+L E + ++K Q + + + + +++ LTNQ +++ E
Sbjct: 445 EELSSKEAQWEELKKKAAGLQAEIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIE 504
Query: 554 DADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKIS 658
++ A ++ E++ R++ + ++
Sbjct: 505 VLKESLTAKEQRAAILQTEVDALRLRLEEKETMLN 539
Score = 38.3 bits (85), Expect = 0.028
Identities = 29/150 (19%), Positives = 68/150 (45%)
Frame = +2
Query: 164 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 343
Q +A R + +N+ ++LQ L + ++ + + L ++ + E+E L E+
Sbjct: 809 QMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESART 868
Query: 344 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 523
++V+++ +EK ++ + + KL QQS E L ++ E + ++
Sbjct: 869 NAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQ 928
Query: 524 QLKEARLLAEDADGKSDEVSRKLAFVEDEL 613
+ A + +DA+ E+S ++E+
Sbjct: 929 EALLAAISEKDANIALLELSSSKKKTQEEV 958
>BC132782-1|AAI32783.1| 1116|Homo sapiens ELKS/RAB6-interacting/CAST
family member 1 protein.
Length = 1116
Score = 52.0 bits (119), Expect = 2e-06
Identities = 52/221 (23%), Positives = 107/221 (48%), Gaps = 12/221 (5%)
Frame = +2
Query: 98 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVREL-----QKKLAQVEEDLIL 262
+KK + +K+E + KA +AR + ++++ RE+ + AQ E D +L
Sbjct: 705 QKKEECLKMESQ--LKKAHEAALEARASPEMSDRIQHLEREITRYKDESSKAQAEVDRLL 762
Query: 263 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 442
L++ + +K+K++ E +V N+KV ++ + +++S Q L EA++
Sbjct: 763 EI--LKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSA---QMLEEARRR 817
Query: 443 ADENNRMCKVLENRAQQDEERMDQLTNQLKEA-RLLAEDADGKSDEVSRKLAFVE--DEL 613
D N + L++ ++ ++R+++L L+E+ ++ AE + E S + + +EL
Sbjct: 818 EDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEEL 877
Query: 614 EVAEDRVK----SGDAKISXLEXELKVVGNSLKSLEVSEXK 724
+A ++VK S AK+S + L L +L K
Sbjct: 878 LMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRK 918
Score = 50.0 bits (114), Expect = 9e-06
Identities = 47/224 (20%), Positives = 100/224 (44%), Gaps = 3/224 (1%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
+Q+AA + ++ EK+ ++K +Q +D E+ +L+ L E
Sbjct: 514 EQRAAILQTEVDALRLRLEEKETMLNKKT---KQIQDMAEEKGTQAGEIHDLKDMLDVKE 570
Query: 248 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 427
+ + + K+E + L +KEKQ+ ++L +V+ ++ D ++ T ++ L
Sbjct: 571 RKVNVLQKKIENLQEQLRDKEKQM-------SSLKERVKSLQADTTNTDTALTTLEEALA 623
Query: 428 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 607
E +++ + ++ E R + + E+ +++ N K+ + L E ++S K A + D
Sbjct: 624 EKERTIE------RLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLD 677
Query: 608 ELEVAEDRVKSG---DAKISXLEXELKVVGNSLKSLEVSEXKAN 730
E A SG D+++ LE L+ +E KA+
Sbjct: 678 LKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAH 721
Score = 42.7 bits (96), Expect = 0.001
Identities = 25/155 (16%), Positives = 71/155 (45%)
Frame = +2
Query: 194 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIE 373
E + ++ +++ L +EE++ + K+ + ++ EE+ KQ+ + + KV+Q++
Sbjct: 385 EMKDSKISSMERGLRDLEEEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKNKVEQLK 444
Query: 374 EDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAE 553
E+L E + ++K Q + + + + +++ LTNQ +++ E
Sbjct: 445 EELSSKEAQWEELKKKAAGLQAEIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIE 504
Query: 554 DADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKIS 658
++ A ++ E++ R++ + ++
Sbjct: 505 VLKESLTAKEQRAAILQTEVDALRLRLEEKETMLN 539
Score = 38.3 bits (85), Expect = 0.028
Identities = 29/150 (19%), Positives = 68/150 (45%)
Frame = +2
Query: 164 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 343
Q +A R + +N+ ++LQ L + ++ + + L ++ + E+E L E+
Sbjct: 809 QMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESART 868
Query: 344 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 523
++V+++ +EK ++ + + KL QQS E L ++ E + ++
Sbjct: 869 NAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQ 928
Query: 524 QLKEARLLAEDADGKSDEVSRKLAFVEDEL 613
+ A + +DA+ E+S ++E+
Sbjct: 929 EALLAAISEKDANIALLELSSSKKKTQEEV 958
>AC012487-1|AAX88838.1| 1583|Homo sapiens unknown protein.
Length = 1583
Score = 52.0 bits (119), Expect = 2e-06
Identities = 35/203 (17%), Positives = 99/203 (48%), Gaps = 5/203 (2%)
Frame = +2
Query: 86 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 265
++ ++ ++Q K + M + + ++ A+ L +N E+ + ++ + ++ + L
Sbjct: 1023 LEELQVQLQKQKKQLQKTMQELELVKKDAQQTTL----MNMEIADYERLMKELNQKLTNK 1078
Query: 266 KNKLEQANKDLE-EKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 442
NK+E ++++ +K+KQ T E E+ +L VQQ EE K ++ +++L +++Q+
Sbjct: 1079 NNKIEDLEQEIKIQKQKQETLQE-EITSLQSSVQQYEEKNTKIKQLLVKTKKELADSKQA 1137
Query: 443 ADENNRMCKVLENRAQQDEERMD----QLTNQLKEARLLAEDADGKSDEVSRKLAFVEDE 610
++ + L+ + +++++ QL E + E +++ R L+ +
Sbjct: 1138 ETDHLILQASLKGELEASQQQVEVYKIQLAEITSEKHKIHEHLKTSAEQHQRTLSAYQQR 1197
Query: 611 LEVAEDRVKSGDAKISXLEXELK 679
+ ++ ++ A+ + + E +
Sbjct: 1198 VTALQEECRAAKAEQATVTSEFE 1220
Score = 50.8 bits (116), Expect = 5e-06
Identities = 45/204 (22%), Positives = 99/204 (48%), Gaps = 4/204 (1%)
Frame = +2
Query: 104 KMQAMKLEKDNAM-DKADTCEQQARDANLR--AEKVNEEVRELQKKLAQVEEDLILNKNK 274
++Q +++++ AM DK E+ ++ ++ A VNE + ELQ +L + ++ L +
Sbjct: 985 EVQILEVQRAKAMVDKELEAEKLQKEQKIKEHATTVNE-LEELQVQLQKQKKQLQKTMQE 1043
Query: 275 LEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN 454
LE KD + Q T E+A R ++++ + L + +Q++ +Q +
Sbjct: 1044 LELVKKDAQ----QTTLMNMEIADYERLMKELNQKLTNKNNKIEDLEQEIKIQKQKQETL 1099
Query: 455 NRMCKVLENRAQQDEERMDQLTNQL-KEARLLAEDADGKSDEVSRKLAFVEDELEVAEDR 631
L++ QQ EE+ ++ L K + LA+ ++D + + A ++ ELE ++ +
Sbjct: 1100 QEEITSLQSSVQQYEEKNTKIKQLLVKTKKELADSKQAETDHLILQ-ASLKGELEASQQQ 1158
Query: 632 VKSGDAKISXLEXELKVVGNSLKS 703
V+ +++ + E + LK+
Sbjct: 1159 VEVYKIQLAEITSEKHKIHEHLKT 1182
Score = 40.3 bits (90), Expect = 0.007
Identities = 40/203 (19%), Positives = 91/203 (44%), Gaps = 8/203 (3%)
Frame = +2
Query: 95 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKV------NEEVREL--QKKLAQVEE 250
+K + +LE N + + + Q + + EK +E ++ L QK+L
Sbjct: 763 MKNANEKTRLENQNLLIQVEEVSQTCSKSEIHNEKEKCFIKEHENLKPLLEQKELRDRRA 822
Query: 251 DLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLE 430
+LIL K+ L K K L++ V L K++ +E++ ++ EE+ + ++
Sbjct: 823 ELILLKDSLA---KSPSVKNDPLSS----VKELEEKIENLEKECKEKEEKINKIKLVAVK 875
Query: 431 AQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDE 610
A++ D + + + ++ + DQL+ +++ AE E ++ ++
Sbjct: 876 AKKELDSSRKETQTVKEELESLRSEKDQLSASMRDLIQGAESYKNLLLEYEKQ----SEQ 931
Query: 611 LEVAEDRVKSGDAKISXLEXELK 679
L+V ++R + + +I L +L+
Sbjct: 932 LDVEKERANNFEHRIEDLTRQLR 954
Score = 38.7 bits (86), Expect = 0.021
Identities = 38/182 (20%), Positives = 87/182 (47%), Gaps = 15/182 (8%)
Frame = +2
Query: 116 MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN-----KLE 280
+K ++ ++ + + + RD + +E+ E+Q + ++ DL+ KN +LE
Sbjct: 714 IKCLQEESVVQCEELKSLLRDYEQEKVLLRKELEEIQSEKEALQSDLLEMKNANEKTRLE 773
Query: 281 QANKDLEEKEKQLTATEAEVAALNRKV-----QQIEEDLEKSEERSGTAQQKLLE---AQ 436
N ++ +E T +++E+ K + ++ LE+ E R A+ LL+ A+
Sbjct: 774 NQNLLIQVEEVSQTCSKSEIHNEKEKCFIKEHENLKPLLEQKELRDRRAELILLKDSLAK 833
Query: 437 QSADENNRMCKV--LENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDE 610
+ +N+ + V LE + + E+ + ++ + +L+A A + D ++ V++E
Sbjct: 834 SPSVKNDPLSSVKELEEKIENLEKECKEKEEKINKIKLVAVKAKKELDSSRKETQTVKEE 893
Query: 611 LE 616
LE
Sbjct: 894 LE 895
Score = 34.3 bits (75), Expect = 0.46
Identities = 53/215 (24%), Positives = 96/215 (44%), Gaps = 17/215 (7%)
Frame = +2
Query: 86 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILN 265
MD KK + E+ ++ EQ + + +KVNE L++ L + ++ N
Sbjct: 509 MDNFHKKCER---EERLILELGKKVEQTIQYNSELEQKVNELTGGLEETLKEKDQ----N 561
Query: 266 KNKLEQANKDLEEKEKQLTATEAEVAAL---NRKV----QQIEEDLEK--SEERSGTAQQ 418
KLE+ ++ + AEV +L N K+ +Q+ DLE S++ ++
Sbjct: 562 DQKLEKLMVQMKVLSEDKEVLSAEVKSLYEENNKLSSEKKQLSRDLEVFLSQKEDVILKE 621
Query: 419 KLLEAQQS----ADENNRMCKVLENRAQQDEERMDQLTNQLKE-ARLLAEDADGKSDEVS 583
+ + ++ +E + + K+LEN Q QL LKE ++ED++ K D V+
Sbjct: 622 HITQLEKKLQLMVEEQDNLNKLLENEQVQKLFVKTQLYGFLKEMGSEVSEDSEEK-DVVN 680
Query: 584 RKLAFVEDELEVAEDRVK---SGDAKISXLEXELK 679
A E ++ E++ D K+ LE E+K
Sbjct: 681 VLQAVGESLAKINEEKCNLAFQRDEKVLELEKEIK 715
>AB053471-1|BAC54110.1| 1116|Homo sapiens ELKS epsilon protein.
Length = 1116
Score = 52.0 bits (119), Expect = 2e-06
Identities = 52/221 (23%), Positives = 107/221 (48%), Gaps = 12/221 (5%)
Frame = +2
Query: 98 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVREL-----QKKLAQVEEDLIL 262
+KK + +K+E + KA +AR + ++++ RE+ + AQ E D +L
Sbjct: 705 QKKEECLKMESQ--LKKAHEAALEARASPEMSDRIQHLEREITRYKDESSKAQAEVDRLL 762
Query: 263 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 442
L++ + +K+K++ E +V N+KV ++ + +++S Q L EA++
Sbjct: 763 EI--LKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSA---QMLEEARRR 817
Query: 443 ADENNRMCKVLENRAQQDEERMDQLTNQLKEA-RLLAEDADGKSDEVSRKLAFVE--DEL 613
D N + L++ ++ ++R+++L L+E+ ++ AE + E S + + +EL
Sbjct: 818 EDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEEL 877
Query: 614 EVAEDRVK----SGDAKISXLEXELKVVGNSLKSLEVSEXK 724
+A ++VK S AK+S + L L +L K
Sbjct: 878 LMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRK 918
Score = 50.0 bits (114), Expect = 9e-06
Identities = 47/224 (20%), Positives = 100/224 (44%), Gaps = 3/224 (1%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
+Q+AA + ++ EK+ ++K +Q +D E+ +L+ L E
Sbjct: 514 EQRAAILQTEVDALRLRLEEKETMLNKKT---KQIQDMAEEKGTQAGEIHDLKDMLDVKE 570
Query: 248 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 427
+ + + K+E + L +KEKQ+ ++L +V+ ++ D ++ T ++ L
Sbjct: 571 RKVNVLQKKIENLQEQLRDKEKQM-------SSLKERVKSLQADTTNTDTALTTLEEALA 623
Query: 428 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 607
E +++ + ++ E R + + E+ +++ N K+ + L E ++S K A + D
Sbjct: 624 EKERTIE------RLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLD 677
Query: 608 ELEVAEDRVKSG---DAKISXLEXELKVVGNSLKSLEVSEXKAN 730
E A SG D+++ LE L+ +E KA+
Sbjct: 678 LKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAH 721
Score = 42.7 bits (96), Expect = 0.001
Identities = 25/155 (16%), Positives = 71/155 (45%)
Frame = +2
Query: 194 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIE 373
E + ++ +++ L +EE++ + K+ + ++ EE+ KQ+ + + KV+Q++
Sbjct: 385 EMKDSKISSMERGLRDLEEEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKNKVEQLK 444
Query: 374 EDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAE 553
E+L E + ++K Q + + + + +++ LTNQ +++ E
Sbjct: 445 EELSSKEAQWEELKKKAAGLQAEIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIE 504
Query: 554 DADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKIS 658
++ A ++ E++ R++ + ++
Sbjct: 505 VLKESLTAKEQRAAILQTEVDALRLRLEEKETMLN 539
Score = 38.3 bits (85), Expect = 0.028
Identities = 29/150 (19%), Positives = 68/150 (45%)
Frame = +2
Query: 164 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 343
Q +A R + +N+ ++LQ L + ++ + + L ++ + E+E L E+
Sbjct: 809 QMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESART 868
Query: 344 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 523
++V+++ +EK ++ + + KL QQS E L ++ E + ++
Sbjct: 869 NAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQ 928
Query: 524 QLKEARLLAEDADGKSDEVSRKLAFVEDEL 613
+ A + +DA+ E+S ++E+
Sbjct: 929 EALLAAISEKDANIALLELSSSKKKTQEEV 958
>AB053470-1|BAC54109.1| 1088|Homo sapiens ELKS delta protein.
Length = 1088
Score = 52.0 bits (119), Expect = 2e-06
Identities = 52/221 (23%), Positives = 107/221 (48%), Gaps = 12/221 (5%)
Frame = +2
Query: 98 KKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVREL-----QKKLAQVEEDLIL 262
+KK + +K+E + KA +AR + ++++ RE+ + AQ E D +L
Sbjct: 677 QKKEECLKMESQ--LKKAHEAALEARASPEMSDRIQHLEREITRYKDESSKAQAEVDRLL 734
Query: 263 NKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQS 442
L++ + +K+K++ E +V N+KV ++ + +++S Q L EA++
Sbjct: 735 EI--LKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSA---QMLEEARRR 789
Query: 443 ADENNRMCKVLENRAQQDEERMDQLTNQLKEA-RLLAEDADGKSDEVSRKLAFVE--DEL 613
D N + L++ ++ ++R+++L L+E+ ++ AE + E S + + +EL
Sbjct: 790 EDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEEL 849
Query: 614 EVAEDRVK----SGDAKISXLEXELKVVGNSLKSLEVSEXK 724
+A ++VK S AK+S + L L +L K
Sbjct: 850 LMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRK 890
Score = 50.0 bits (114), Expect = 9e-06
Identities = 47/224 (20%), Positives = 100/224 (44%), Gaps = 3/224 (1%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
+Q+AA + ++ EK+ ++K +Q +D E+ +L+ L E
Sbjct: 486 EQRAAILQTEVDALRLRLEEKETMLNKKT---KQIQDMAEEKGTQAGEIHDLKDMLDVKE 542
Query: 248 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 427
+ + + K+E + L +KEKQ+ ++L +V+ ++ D ++ T ++ L
Sbjct: 543 RKVNVLQKKIENLQEQLRDKEKQM-------SSLKERVKSLQADTTNTDTALTTLEEALA 595
Query: 428 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 607
E +++ + ++ E R + + E+ +++ N K+ + L E ++S K A + D
Sbjct: 596 EKERTIE------RLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLD 649
Query: 608 ELEVAEDRVKSG---DAKISXLEXELKVVGNSLKSLEVSEXKAN 730
E A SG D+++ LE L+ +E KA+
Sbjct: 650 LKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAH 693
Score = 45.6 bits (103), Expect = 2e-04
Identities = 27/172 (15%), Positives = 79/172 (45%)
Frame = +2
Query: 194 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIE 373
E + ++ +++ L +EE++ + K+ + ++ EE+ KQ+ + + K+ Q++
Sbjct: 385 EMKDSKISSMERGLRDLEEEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKNKIGQVK 444
Query: 374 EDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAE 553
++L + + Q KL ++ + +VL+ E+R L ++ RL E
Sbjct: 445 QELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLE 504
Query: 554 DADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLE 709
+ + ++ ++++ + +E + + E ++ V+ +++L+
Sbjct: 505 EKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQ 556
Score = 38.3 bits (85), Expect = 0.028
Identities = 29/150 (19%), Positives = 68/150 (45%)
Frame = +2
Query: 164 QQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVA 343
Q +A R + +N+ ++LQ L + ++ + + L ++ + E+E L E+
Sbjct: 781 QMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESART 840
Query: 344 ALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTN 523
++V+++ +EK ++ + + KL QQS E L ++ E + ++
Sbjct: 841 NAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQ 900
Query: 524 QLKEARLLAEDADGKSDEVSRKLAFVEDEL 613
+ A + +DA+ E+S ++E+
Sbjct: 901 EALLAAISEKDANIALLELSSSKKKTQEEV 930
>Z75311-1|CAA99729.1| 1318|Homo sapiens RAD50 homologue hsRAD50
protein.
Length = 1318
Score = 51.6 bits (118), Expect = 3e-06
Identities = 41/189 (21%), Positives = 87/189 (46%), Gaps = 1/189 (0%)
Frame = +2
Query: 167 QARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAA 346
Q D + ++VN+E +E Q KL V + LN+ ++ + ++ + ++E
Sbjct: 823 QGIDLDRTVQQVNQEKQEKQHKLDTVSSKIELNRKLIQDQQEQIQHLKSTTNELKSEKLQ 882
Query: 347 LNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQ 526
++ +Q+ ++ E++ E S Q E + + ++ + + LE Q+ EE L N+
Sbjct: 883 ISTNLQRRQQLEEQTVELSTEVQSLYREIKDAKEQVSPLETTLEKFQQEKEE----LINK 938
Query: 527 LKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSG-DAKISXLEXELKVVGNSLKS 703
+ +A+D K +++ K+ + ++ E+ ++ G D + E EL V L
Sbjct: 939 KNTSNKIAQD---KLNDIKEKVKNIHGYMKDIENHIQDGKDDYMKQKETELNKVIAQLSE 995
Query: 704 LEVSEXKAN 730
E + K N
Sbjct: 996 CEKHKEKIN 1004
Score = 49.2 bits (112), Expect = 2e-05
Identities = 41/182 (22%), Positives = 89/182 (48%), Gaps = 13/182 (7%)
Frame = +2
Query: 203 NEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAAL------NRKVQ 364
++E+ + + +LA++ ++L ++ N +LE KE+QL++ E ++ + +
Sbjct: 590 SKEINQTRDRLAKLNKELASSEQNKNHINNELERKEEQLSSYEDKLFDVCGSQDFESDLD 649
Query: 365 QIEEDLEKS-EERSGTAQQKLLEAQ---QSADENNRMCKVLENRAQQDEERMDQLTNQLK 532
+++E++EKS ++R+ A + +Q Q DEN C V + Q + E + +++
Sbjct: 650 RLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSCCPVCQRVFQTEAELQEAISDLQS 709
Query: 533 EARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAK---ISXLEXELKVVGNSLKS 703
+ RL + E+ +K ++ L +A R D K I L +L+ V ++
Sbjct: 710 KLRLAPDKLKSTESELKKKEKRRDEMLGLAPMRQSIIDLKEKEIPELRNKLQNVNRDIQR 769
Query: 704 LE 709
L+
Sbjct: 770 LK 771
Score = 39.5 bits (88), Expect = 0.012
Identities = 41/176 (23%), Positives = 84/176 (47%), Gaps = 3/176 (1%)
Frame = +2
Query: 185 LRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQ 364
L +K+ EL+KK + D +L + Q+ DL KEK++ ++ +NR +Q
Sbjct: 713 LAPDKLKSTESELKKK--EKRRDEMLGLAPMRQSIIDL--KEKEIPELRNKLQNVNRDIQ 768
Query: 365 QIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL 544
+++ D+E+ E GT ++ ++SA ++E R Q + + +++ Q + A+L
Sbjct: 769 RLKNDIEEQETLLGT----IMPEEESAKVCLTDVTIME-RFQMELKDVERKIAQ-QAAKL 822
Query: 545 LAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXE---LKVVGNSLKS 703
D D +V+++ + +L+ +++ I + + LK N LKS
Sbjct: 823 QGIDLDRTVQQVNQEKQEKQHKLDTVSSKIELNRKLIQDQQEQIQHLKSTTNELKS 878
Score = 37.9 bits (84), Expect = 0.037
Identities = 33/161 (20%), Positives = 77/161 (47%), Gaps = 5/161 (3%)
Frame = +2
Query: 95 IKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNK 274
++ ++ + EK+ ++K +T + A+D + + E+V+ + + +E N
Sbjct: 921 LETTLEKFQQEKEELINKKNTSNKIAQD---KLNDIKEKVKNIHGYMKDIE-------NH 970
Query: 275 LEQANKD-LEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGT--AQQKLLEAQQSA 445
++ D +++KE +L A+++ + ++I ED+ + T Q++ L+ +
Sbjct: 971 IQDGKDDYMKQKETELNKVIAQLSECEKHKEKINEDMRLMRQDIDTQKIQERWLQDNLTL 1030
Query: 446 DENNRMCKVLENRAQQDEERMDQL-TNQLK-EARLLAEDAD 562
+ N K +E +Q + M Q+ Q+K E + L E+ D
Sbjct: 1031 RKRNEELKEVEEEGKQHLKEMGQMQVLQMKSEHQKLEENID 1071
Score = 35.9 bits (79), Expect = 0.15
Identities = 36/170 (21%), Positives = 80/170 (47%), Gaps = 3/170 (1%)
Frame = +2
Query: 188 RAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTAT---EAEVAALNRK 358
+A ++ +++ + +L +E + +N+L+ L+E E L+ + E+ AL+ +
Sbjct: 225 KACEIRDQITSKEAQLTSSKEIVKSYENELDPLKNRLKEIEHNLSKIMKLDNEIKALDSR 284
Query: 359 VQQIEEDLEKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEA 538
+Q+E+D + EE+ Q E N++ + R D R +L KE+
Sbjct: 285 KKQMEKDNSELEEKMEKVFQGTDEQLNDLYHNHQRTVREKERKLVDCHR--ELEKLNKES 342
Query: 539 RLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVG 688
RLL ++ E R ++ + + ++ +++ D+ I L +L++ G
Sbjct: 343 RLLNQEKSELLVEQGR----LQLQADRHQEHIRARDSLIQSLATQLELDG 388
>Z22664-1|CAA80377.1| 595|Homo sapiens membrane organizing protein
protein.
Length = 595
Score = 51.6 bits (118), Expect = 3e-06
Identities = 50/182 (27%), Positives = 96/182 (52%), Gaps = 8/182 (4%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVR-ELQKKLAQV 244
++KA +++ + K QA + + M++ ++ AR+ +R E E R EL+++L Q+
Sbjct: 310 RRKADSLEVQQMKAQAREEKARKQMER----QRLAREKQMREEA--ERTRDELERRLLQM 363
Query: 245 EEDLILNKNKLEQANK--DLEEKEKQLTATEAEVAA-----LNRKVQQIEEDLEKSEERS 403
+E+ + L ++ + DL ++ Q+T EA++ A +++Q+I+ ++EE
Sbjct: 364 KEEATMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTEEEK 423
Query: 404 GTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVS 583
+QK+LEA+ A +M + E RA++ DQL L+EAR A K E++
Sbjct: 424 RLMEQKVLEAEVLA---LKMAEESERRAKE----ADQLKQDLQEAREAERRAKQKLLEIA 476
Query: 584 RK 589
K
Sbjct: 477 TK 478
>Y18000-2|CAA76993.1| 615|Homo sapiens NF2 protein protein.
Length = 615
Score = 51.6 bits (118), Expect = 3e-06
Identities = 50/182 (27%), Positives = 96/182 (52%), Gaps = 8/182 (4%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVR-ELQKKLAQV 244
++KA +++ + K QA + + M++ ++ AR+ +R E E R EL+++L Q+
Sbjct: 310 RRKADSLEVQQMKAQAREEKARKQMER----QRLAREKQMREEA--ERTRDELERRLLQM 363
Query: 245 EEDLILNKNKLEQANK--DLEEKEKQLTATEAEVAA-----LNRKVQQIEEDLEKSEERS 403
+E+ + L ++ + DL ++ Q+T EA++ A +++Q+I+ ++EE
Sbjct: 364 KEEATMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTEEEK 423
Query: 404 GTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVS 583
+QK+LEA+ A +M + E RA++ DQL L+EAR A K E++
Sbjct: 424 RLMEQKVLEAEVLA---LKMAEESERRAKE----ADQLKQDLQEAREAERRAKQKLLEIA 476
Query: 584 RK 589
K
Sbjct: 477 TK 478
>Y18000-1|CAA76992.1| 595|Homo sapiens NF2 protein protein.
Length = 595
Score = 51.6 bits (118), Expect = 3e-06
Identities = 50/182 (27%), Positives = 96/182 (52%), Gaps = 8/182 (4%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVR-ELQKKLAQV 244
++KA +++ + K QA + + M++ ++ AR+ +R E E R EL+++L Q+
Sbjct: 310 RRKADSLEVQQMKAQAREEKARKQMER----QRLAREKQMREEA--ERTRDELERRLLQM 363
Query: 245 EEDLILNKNKLEQANK--DLEEKEKQLTATEAEVAA-----LNRKVQQIEEDLEKSEERS 403
+E+ + L ++ + DL ++ Q+T EA++ A +++Q+I+ ++EE
Sbjct: 364 KEEATMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTEEEK 423
Query: 404 GTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVS 583
+QK+LEA+ A +M + E RA++ DQL L+EAR A K E++
Sbjct: 424 RLMEQKVLEAEVLA---LKMAEESERRAKE----ADQLKQDLQEAREAERRAKQKLLEIA 476
Query: 584 RK 589
K
Sbjct: 477 TK 478
>X72655-1|CAA51220.1| 595|Homo sapiens schwannomin protein.
Length = 595
Score = 51.6 bits (118), Expect = 3e-06
Identities = 50/182 (27%), Positives = 96/182 (52%), Gaps = 8/182 (4%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVR-ELQKKLAQV 244
++KA +++ + K QA + + M++ ++ AR+ +R E E R EL+++L Q+
Sbjct: 310 RRKADSLEVQQMKAQAREEKARKQMER----QRLAREKQMREEA--ERTRDELERRLLQM 363
Query: 245 EEDLILNKNKLEQANK--DLEEKEKQLTATEAEVAA-----LNRKVQQIEEDLEKSEERS 403
+E+ + L ++ + DL ++ Q+T EA++ A +++Q+I+ ++EE
Sbjct: 364 KEEATMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTEEEK 423
Query: 404 GTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVS 583
+QK+LEA+ A +M + E RA++ DQL L+EAR A K E++
Sbjct: 424 RLMEQKVLEAEVLA---LKMAEESERRAKE----ADQLKQDLQEAREAERRAKQKLLEIA 476
Query: 584 RK 589
K
Sbjct: 477 TK 478
>L11353-1|AAA36212.1| 595|Homo sapiens moesin-ezrin-radixin-like
protein protein.
Length = 595
Score = 51.6 bits (118), Expect = 3e-06
Identities = 50/182 (27%), Positives = 96/182 (52%), Gaps = 8/182 (4%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVR-ELQKKLAQV 244
++KA +++ + K QA + + M++ ++ AR+ +R E E R EL+++L Q+
Sbjct: 310 RRKADSLEVQQMKAQAREEKARKQMER----QRLAREKQMREEA--ERTRDELERRLLQM 363
Query: 245 EEDLILNKNKLEQANK--DLEEKEKQLTATEAEVAA-----LNRKVQQIEEDLEKSEERS 403
+E+ + L ++ + DL ++ Q+T EA++ A +++Q+I+ ++EE
Sbjct: 364 KEEATMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTEEEK 423
Query: 404 GTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVS 583
+QK+LEA+ A +M + E RA++ DQL L+EAR A K E++
Sbjct: 424 RLMEQKVLEAEVLA---LKMAEESERRAKE----ADQLKQDLQEAREAERRAKQKLLEIA 476
Query: 584 RK 589
K
Sbjct: 477 TK 478
>CR456530-1|CAG30416.1| 595|Homo sapiens NF2 protein.
Length = 595
Score = 51.6 bits (118), Expect = 3e-06
Identities = 50/182 (27%), Positives = 96/182 (52%), Gaps = 8/182 (4%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVR-ELQKKLAQV 244
++KA +++ + K QA + + M++ ++ AR+ +R E E R EL+++L Q+
Sbjct: 310 RRKADSLEVQQMKAQAREEKARKQMER----QRLAREKQMREEA--ERTRDELERRLLQM 363
Query: 245 EEDLILNKNKLEQANK--DLEEKEKQLTATEAEVAA-----LNRKVQQIEEDLEKSEERS 403
+E+ + L ++ + DL ++ Q+T EA++ A +++Q+I+ ++EE
Sbjct: 364 KEEATMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTEEEK 423
Query: 404 GTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVS 583
+QK+LEA+ A +M + E RA++ DQL L+EAR A K E++
Sbjct: 424 RLMEQKVLEAEVLA---LKMAEESERRAKE----ADQLKQDLQEAREAERRAKQKLLEIA 476
Query: 584 RK 589
K
Sbjct: 477 TK 478
>BC020257-1|AAH20257.1| 595|Homo sapiens neurofibromin 2 (bilateral
acoustic neuroma) protein.
Length = 595
Score = 51.6 bits (118), Expect = 3e-06
Identities = 50/182 (27%), Positives = 96/182 (52%), Gaps = 8/182 (4%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVR-ELQKKLAQV 244
++KA +++ + K QA + + M++ ++ AR+ +R E E R EL+++L Q+
Sbjct: 310 RRKADSLEVQQMKAQAREEKARKQMER----QRLAREKQMREEA--ERTRDELERRLLQM 363
Query: 245 EEDLILNKNKLEQANK--DLEEKEKQLTATEAEVAA-----LNRKVQQIEEDLEKSEERS 403
+E+ + L ++ + DL ++ Q+T EA++ A +++Q+I+ ++EE
Sbjct: 364 KEEATMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTEEEK 423
Query: 404 GTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVS 583
+QK+LEA+ A +M + E RA++ DQL L+EAR A K E++
Sbjct: 424 RLMEQKVLEAEVLA---LKMAEESERRAKE----ADQLKQDLQEAREAERRAKQKLLEIA 476
Query: 584 RK 589
K
Sbjct: 477 TK 478
>BC003112-1|AAH03112.2| 507|Homo sapiens neurofibromin 2 (bilateral
acoustic neuroma) protein.
Length = 507
Score = 51.6 bits (118), Expect = 3e-06
Identities = 50/182 (27%), Positives = 96/182 (52%), Gaps = 8/182 (4%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVR-ELQKKLAQV 244
++KA +++ + K QA + + M++ ++ AR+ +R E E R EL+++L Q+
Sbjct: 227 RRKADSLEVQQMKAQAREEKARKQMER----QRLAREKQMREEA--ERTRDELERRLLQM 280
Query: 245 EEDLILNKNKLEQANK--DLEEKEKQLTATEAEVAA-----LNRKVQQIEEDLEKSEERS 403
+E+ + L ++ + DL ++ Q+T EA++ A +++Q+I+ ++EE
Sbjct: 281 KEEATMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTEEEK 340
Query: 404 GTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVS 583
+QK+LEA+ A +M + E RA++ DQL L+EAR A K E++
Sbjct: 341 RLMEQKVLEAEVLA---LKMAEESERRAKE----ADQLKQDLQEAREAERRAKQKLLEIA 393
Query: 584 RK 589
K
Sbjct: 394 TK 395
>AY257469-1|AAP13528.1| 2027|Homo sapiens rho/rac-interacting citron
kinase protein.
Length = 2027
Score = 51.6 bits (118), Expect = 3e-06
Identities = 39/177 (22%), Positives = 74/177 (41%)
Frame = +2
Query: 80 ATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLI 259
A +++KK+ E ++ DK EQ+ + R +V + + + +L E
Sbjct: 442 AKTSSMEKKLLIKSKELQDSQDKCHKMEQEMTRLHRRVSEVEAVLSQKEVELKASETQRS 501
Query: 260 LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQ 439
L + L + ++ L EV+ + K Q+ D+ + + +++ E Q
Sbjct: 502 LLEQDLATYITECSSLKRSLEQARMEVSQEDDKALQLLHDIREQSRKLQEIKEQ--EYQA 559
Query: 440 SADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDE 610
+E M LE R D ++L+E+RL AE+ K+ E KL +D+
Sbjct: 560 QVEEMRLMMNQLEEDLVSARRRSDLYESELRESRLAAEEFKRKATECQHKLLKAKDQ 616
Score = 51.2 bits (117), Expect = 4e-06
Identities = 49/183 (26%), Positives = 85/183 (46%), Gaps = 18/183 (9%)
Frame = +2
Query: 86 MDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEE-------VRELQKKLAQV 244
M A ++ + ++ +K +A E Q R + EK++ + + EL+ +L +V
Sbjct: 802 MKAQEEMISELRQQKFYLETQAGKLEAQNRKLEEQLEKISHQDHSDKNRLLELETRLREV 861
Query: 245 ----EEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTA 412
EE + K +L + L+E+E QLTA +A AAL +++Q + +LE++ +
Sbjct: 862 SLEHEEQKLELKRQLTELQLSLQERESQLTALQAARAALESQLRQAKTELEETTAEAEEE 921
Query: 413 QQKLL----EAQQSADENNRMCKV---LENRAQQDEERMDQLTNQLKEARLLAEDADGKS 571
Q L E Q+ D C V LE + Q E +L NQ ++A G +
Sbjct: 922 IQALTAHRDEIQRKFDALRNSCTVITDLEEQLNQLTEDNAELNNQNFYLSKQLDEASGAN 981
Query: 572 DEV 580
DE+
Sbjct: 982 DEI 984
Score = 48.4 bits (110), Expect = 3e-05
Identities = 47/204 (23%), Positives = 96/204 (47%), Gaps = 4/204 (1%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
Q+ A ++ ++ M ++ + +A ++D E + R++ L AE+ + E Q KL + +
Sbjct: 555 QEYQAQVEEMRLMMNQLEEDLVSARRRSDLYESELRESRLAAEEFKRKATECQHKLLKAK 614
Query: 248 EDLILNKNKL-EQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKL 424
+ K ++ E A + E+QL K+Q+++E LEK+ + S A + L
Sbjct: 615 DQ---GKPEVGEYAKLEKINAEQQL------------KIQELQEKLEKAVKASTEATELL 659
Query: 425 LEAQQSADENNRMCKVLENRAQQDEERMDQL--TNQLKEARLLAE-DADGKSDEVSRKLA 595
+Q+ + R + L+NR E +L +L+E A+ A + +K
Sbjct: 660 QNIRQAKERAERELEKLQNREDSSEGIRKKLVEAEELEEKHREAQVSAQHLEVHLKQKEQ 719
Query: 596 FVEDELEVAEDRVKSGDAKISXLE 667
E++++V ++++K A LE
Sbjct: 720 HYEEKIKVLDNQIKKDLADKETLE 743
Score = 42.7 bits (96), Expect = 0.001
Identities = 47/224 (20%), Positives = 103/224 (45%), Gaps = 12/224 (5%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
Q A D I++K A++ D + Q D N N + + + +
Sbjct: 923 QALTAHRDEIQRKFDALRNSCTVITDLEEQLNQLTED-NAELNNQNFYLSKQLDEASGAN 981
Query: 248 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEE---DLEKSEERSGTAQQ 418
++++ +++++ +++ E+E QLT+ + + AL +EE DLE + ++
Sbjct: 982 DEIVQLRSEVDHLRREITEREMQLTSQKQTMEALKTTCTMLEEQVMDLEALNDEL-LEKE 1040
Query: 419 KLLEAQQS--ADENNRM-CKVLENRAQQDEERMD--QLTNQLKEARLLAEDA--DGKSDE 577
+ EA +S DE ++ C+V E + D E+ + ++ E+R + E A + K++
Sbjct: 1041 RQWEAWRSVLGDEKSQFECRVRELQRMLDTEKQSRARADQRITESRQVVELAVKEHKAEI 1100
Query: 578 VSRKLAFVEDEL--EVAEDRVKSGDAKISXLEXELKVVGNSLKS 703
++ + A E +L E D++ + K + LE + + L++
Sbjct: 1101 LALQQALKEQKLKAESLSDKLNDLEKKHAMLEMNARSLQQKLET 1144
Score = 39.5 bits (88), Expect = 0.012
Identities = 49/233 (21%), Positives = 103/233 (44%), Gaps = 30/233 (12%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEK-----VNEEVRELQKK 232
++K +D KK A K +N M + + E + L +K ++ ++R L+++
Sbjct: 722 EEKIKVLDNQIKKDLADKETLENMMQRHEE-EAHEKGKILSEQKAMINAMDSKIRSLEQR 780
Query: 233 LAQVEE--DLILNKNKLEQANKDLEEK-----EKQLTATEAEVAALNRKVQQIEEDLEKS 391
+ ++ E L N + Q N +E+ +Q E + L + +++EE LEK
Sbjct: 781 IVELSEANKLAANSSLFTQRNMKAQEEMISELRQQKFYLETQAGKLEAQNRKLEEQLEKI 840
Query: 392 EERSGTAQQKLLEAQ--------QSADENNRMCKVLENRAQQDEERMDQLT--------- 520
+ + + +LLE + + ++ + + L +ER QLT
Sbjct: 841 SHQDHSDKNRLLELETRLREVSLEHEEQKLELKRQLTELQLSLQERESQLTALQAARAAL 900
Query: 521 -NQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXEL 676
+QL++A+ E+ +++E + L DE++ D +++ I+ LE +L
Sbjct: 901 ESQLRQAKTELEETTAEAEEEIQALTAHRDEIQRKFDALRNSCTVITDLEEQL 953
Score = 34.7 bits (76), Expect = 0.35
Identities = 25/113 (22%), Positives = 55/113 (48%), Gaps = 4/113 (3%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
Q +A I + Q ++L + +Q ++ L+AE +++++ +L+KK A +E
Sbjct: 1073 QSRARADQRITESRQVVELAVKEHKAEILALQQALKEQKLKAESLSDKLNDLEKKHAMLE 1132
Query: 248 EDLILNKNKLEQ----ANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSE 394
+ + KLE + LEE+ K + + + R Q ++E L++++
Sbjct: 1133 MNARSLQQKLETERELKQRLLEEQAKLQQQMDLQKNHIFRLTQGLQEALDRAD 1185
>AF369701-1|AAK54196.1| 590|Homo sapiens neurofibromatosis type 2
protein.
Length = 590
Score = 51.6 bits (118), Expect = 3e-06
Identities = 50/182 (27%), Positives = 96/182 (52%), Gaps = 8/182 (4%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVR-ELQKKLAQV 244
++KA +++ + K QA + + M++ ++ AR+ +R E E R EL+++L Q+
Sbjct: 310 RRKADSLEVQQMKAQAREEKARKQMER----QRLAREKQMREEA--ERTRDELERRLLQM 363
Query: 245 EEDLILNKNKLEQANK--DLEEKEKQLTATEAEVAA-----LNRKVQQIEEDLEKSEERS 403
+E+ + L ++ + DL ++ Q+T EA++ A +++Q+I+ ++EE
Sbjct: 364 KEEATMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTEEEK 423
Query: 404 GTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVS 583
+QK+LEA+ A +M + E RA++ DQL L+EAR A K E++
Sbjct: 424 RLMEQKVLEAEVLA---LKMAEESERRAKE----ADQLKQDLQEAREAERRAKQKLLEIA 476
Query: 584 RK 589
K
Sbjct: 477 TK 478
>AF369665-1|AAK54166.1| 507|Homo sapiens neurofibromatosis type 2
isoform delE2/3 protein.
Length = 507
Score = 51.6 bits (118), Expect = 3e-06
Identities = 50/182 (27%), Positives = 96/182 (52%), Gaps = 8/182 (4%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVR-ELQKKLAQV 244
++KA +++ + K QA + + M++ ++ AR+ +R E E R EL+++L Q+
Sbjct: 227 RRKADSLEVQQMKAQAREEKARKQMER----QRLAREKQMREEA--ERTRDELERRLLQM 280
Query: 245 EEDLILNKNKLEQANK--DLEEKEKQLTATEAEVAA-----LNRKVQQIEEDLEKSEERS 403
+E+ + L ++ + DL ++ Q+T EA++ A +++Q+I+ ++EE
Sbjct: 281 KEEATMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTEEEK 340
Query: 404 GTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVS 583
+QK+LEA+ A +M + E RA++ DQL L+EAR A K E++
Sbjct: 341 RLMEQKVLEAEVLA---LKMAEESERRAKE----ADQLKQDLQEAREAERRAKQKLLEIA 393
Query: 584 RK 589
K
Sbjct: 394 TK 395
>AF369664-1|AAK54165.1| 549|Homo sapiens neurofibromatosis type 2
isoform delE3 protein.
Length = 549
Score = 51.6 bits (118), Expect = 3e-06
Identities = 50/182 (27%), Positives = 96/182 (52%), Gaps = 8/182 (4%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVR-ELQKKLAQV 244
++KA +++ + K QA + + M++ ++ AR+ +R E E R EL+++L Q+
Sbjct: 269 RRKADSLEVQQMKAQAREEKARKQMER----QRLAREKQMREEA--ERTRDELERRLLQM 322
Query: 245 EEDLILNKNKLEQANK--DLEEKEKQLTATEAEVAA-----LNRKVQQIEEDLEKSEERS 403
+E+ + L ++ + DL ++ Q+T EA++ A +++Q+I+ ++EE
Sbjct: 323 KEEATMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTEEEK 382
Query: 404 GTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVS 583
+QK+LEA+ A +M + E RA++ DQL L+EAR A K E++
Sbjct: 383 RLMEQKVLEAEVLA---LKMAEESERRAKE----ADQLKQDLQEAREAERRAKQKLLEIA 435
Query: 584 RK 589
K
Sbjct: 436 TK 437
>AF369663-1|AAK54164.1| 548|Homo sapiens neurofibromatosis type 2
isoform delE2 protein.
Length = 548
Score = 51.6 bits (118), Expect = 3e-06
Identities = 50/182 (27%), Positives = 96/182 (52%), Gaps = 8/182 (4%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVR-ELQKKLAQV 244
++KA +++ + K QA + + M++ ++ AR+ +R E E R EL+++L Q+
Sbjct: 268 RRKADSLEVQQMKAQAREEKARKQMER----QRLAREKQMREEA--ERTRDELERRLLQM 321
Query: 245 EEDLILNKNKLEQANK--DLEEKEKQLTATEAEVAA-----LNRKVQQIEEDLEKSEERS 403
+E+ + L ++ + DL ++ Q+T EA++ A +++Q+I+ ++EE
Sbjct: 322 KEEATMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTEEEK 381
Query: 404 GTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVS 583
+QK+LEA+ A +M + E RA++ DQL L+EAR A K E++
Sbjct: 382 RLMEQKVLEAEVLA---LKMAEESERRAKE----ADQLKQDLQEAREAERRAKQKLLEIA 434
Query: 584 RK 589
K
Sbjct: 435 TK 436
>AF369662-1|AAK54163.1| 590|Homo sapiens neurofibromatosis type 2
isoform II protein.
Length = 590
Score = 51.6 bits (118), Expect = 3e-06
Identities = 50/182 (27%), Positives = 96/182 (52%), Gaps = 8/182 (4%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVR-ELQKKLAQV 244
++KA +++ + K QA + + M++ ++ AR+ +R E E R EL+++L Q+
Sbjct: 310 RRKADSLEVQQMKAQAREEKARKQMER----QRLAREKQMREEA--ERTRDELERRLLQM 363
Query: 245 EEDLILNKNKLEQANK--DLEEKEKQLTATEAEVAA-----LNRKVQQIEEDLEKSEERS 403
+E+ + L ++ + DL ++ Q+T EA++ A +++Q+I+ ++EE
Sbjct: 364 KEEATMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTEEEK 423
Query: 404 GTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVS 583
+QK+LEA+ A +M + E RA++ DQL L+EAR A K E++
Sbjct: 424 RLMEQKVLEAEVLA---LKMAEESERRAKE----ADQLKQDLQEAREAERRAKQKLLEIA 476
Query: 584 RK 589
K
Sbjct: 477 TK 478
>AF369661-1|AAK54162.1| 595|Homo sapiens neurofibromatosis type 2
isoform I protein.
Length = 595
Score = 51.6 bits (118), Expect = 3e-06
Identities = 50/182 (27%), Positives = 96/182 (52%), Gaps = 8/182 (4%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVR-ELQKKLAQV 244
++KA +++ + K QA + + M++ ++ AR+ +R E E R EL+++L Q+
Sbjct: 310 RRKADSLEVQQMKAQAREEKARKQMER----QRLAREKQMREEA--ERTRDELERRLLQM 363
Query: 245 EEDLILNKNKLEQANK--DLEEKEKQLTATEAEVAA-----LNRKVQQIEEDLEKSEERS 403
+E+ + L ++ + DL ++ Q+T EA++ A +++Q+I+ ++EE
Sbjct: 364 KEEATMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTEEEK 423
Query: 404 GTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVS 583
+QK+LEA+ A +M + E RA++ DQL L+EAR A K E++
Sbjct: 424 RLMEQKVLEAEVLA---LKMAEESERRAKE----ADQLKQDLQEAREAERRAKQKLLEIA 476
Query: 584 RK 589
K
Sbjct: 477 TK 478
>AF369658-1|AAK54161.1| 590|Homo sapiens neurofibromatosis type 2
isoform II protein.
Length = 590
Score = 51.6 bits (118), Expect = 3e-06
Identities = 50/182 (27%), Positives = 96/182 (52%), Gaps = 8/182 (4%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVR-ELQKKLAQV 244
++KA +++ + K QA + + M++ ++ AR+ +R E E R EL+++L Q+
Sbjct: 310 RRKADSLEVQQMKAQAREEKARKQMER----QRLAREKQMREEA--ERTRDELERRLLQM 363
Query: 245 EEDLILNKNKLEQANK--DLEEKEKQLTATEAEVAA-----LNRKVQQIEEDLEKSEERS 403
+E+ + L ++ + DL ++ Q+T EA++ A +++Q+I+ ++EE
Sbjct: 364 KEEATMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTEEEK 423
Query: 404 GTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVS 583
+QK+LEA+ A +M + E RA++ DQL L+EAR A K E++
Sbjct: 424 RLMEQKVLEAEVLA---LKMAEESERRAKE----ADQLKQDLQEAREAERRAKQKLLEIA 476
Query: 584 RK 589
K
Sbjct: 477 TK 478
>AF369657-1|AAK54160.1| 595|Homo sapiens neurofibromatosis type 2
isoform I protein.
Length = 595
Score = 51.6 bits (118), Expect = 3e-06
Identities = 50/182 (27%), Positives = 96/182 (52%), Gaps = 8/182 (4%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVR-ELQKKLAQV 244
++KA +++ + K QA + + M++ ++ AR+ +R E E R EL+++L Q+
Sbjct: 310 RRKADSLEVQQMKAQAREEKARKQMER----QRLAREKQMREEA--ERTRDELERRLLQM 363
Query: 245 EEDLILNKNKLEQANK--DLEEKEKQLTATEAEVAA-----LNRKVQQIEEDLEKSEERS 403
+E+ + L ++ + DL ++ Q+T EA++ A +++Q+I+ ++EE
Sbjct: 364 KEEATMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTEEEK 423
Query: 404 GTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVS 583
+QK+LEA+ A +M + E RA++ DQL L+EAR A K E++
Sbjct: 424 RLMEQKVLEAEVLA---LKMAEESERRAKE----ADQLKQDLQEAREAERRAKQKLLEIA 476
Query: 584 RK 589
K
Sbjct: 477 TK 478
>AB209115-1|BAD92352.1| 1065|Homo sapiens restin isoform a variant
protein.
Length = 1065
Score = 51.6 bits (118), Expect = 3e-06
Identities = 45/229 (19%), Positives = 108/229 (47%), Gaps = 12/229 (5%)
Frame = +2
Query: 77 AATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANL--RAEKVNE-EVRELQK-KLAQV 244
A M+A++ K+ + EK+N+++ + +A D +L + +N+ + E++K K A+
Sbjct: 429 AKEMEALRAKLMKVIKEKENSLEAIRSKLDKAEDQHLVEMEDTLNKLQEAEIKKEKFAEA 488
Query: 245 EEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSG---TAQ 415
E+ + + +++ L +KE+Q +++ L + +E + +ER A+
Sbjct: 489 SEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDEREEQLIKAK 548
Query: 416 QKL----LEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVS 583
+KL E + + +N+ + + + E +++L +L +A A ++++
Sbjct: 549 EKLENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMT 608
Query: 584 RKLAFVEDE-LEVAEDRVKSGDAKISXLEXELKVVGNSLKSLEVSEXKA 727
K + E + E+ K + K+S LE +++ N + L+ +A
Sbjct: 609 VKAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQELKARYERA 657
Score = 47.2 bits (107), Expect = 6e-05
Identities = 67/239 (28%), Positives = 102/239 (42%), Gaps = 20/239 (8%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVR--------EL 223
QQ+AA +KK KL + K +T Q ++ R E+ E + L
Sbjct: 615 QQEAAKKHEEEKKELERKLS--DLEKKMETSHNQCQELKARYERATSETKTKHEEILQNL 672
Query: 224 QKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERS 403
QK L E+ L + + ++LEE KQ A +A+ A QI E + K E++
Sbjct: 673 QKTLLDTEDKLKGAREENSGLLQELEELRKQ--AEKAKAAQTAEDAMQIMEQMTK--EKT 728
Query: 404 GTAQQKLLEAQQSADENNRMCKVLENRAQQDEE---RMDQLT--NQ-----LKEARLLAE 553
T Q +A N + + EN + EE + LT NQ KE L +
Sbjct: 729 ETLASLEDTKQTNAKLQNELDTLKENNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQ 788
Query: 554 DADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKIS--XLEXELKVVGNSLKSLEVSEXK 724
A KS ++S A E+ +++AE+ +S D S LE E V+ N L ++ E K
Sbjct: 789 AAAQKSQQLS---ALQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKRESK 844
Score = 35.9 bits (79), Expect = 0.15
Identities = 43/197 (21%), Positives = 82/197 (41%)
Frame = +2
Query: 47 FNSTGP*QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQ 226
F ST P + KA + + A L++ + + A + R + + E
Sbjct: 34 FPSTTPAKAKANAVRRVMATTSA-SLKRSPSASSLSSMSSVASSVSSRPSRTGL-LTETS 91
Query: 227 KKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSG 406
+ A+ + L++ + +E+ + AEVA V +IE++L + R G
Sbjct: 92 SRYARKISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALA--RDG 149
Query: 407 TAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSR 586
Q +LE + D+ M + D E+++ L NQL+E + ED + +E S
Sbjct: 150 H-DQHVLELEAKMDQLRTMVEAA------DREKVE-LLNQLEEEKRKVEDLQFRVEEESI 201
Query: 587 KLAFVEDELEVAEDRVK 637
+E + ++ R+K
Sbjct: 202 TKGDLETQTKLEHARIK 218
>L02320-1|AAA36541.1| 583|Homo sapiens radixin protein.
Length = 583
Score = 51.2 bits (117), Expect = 4e-06
Identities = 36/166 (21%), Positives = 69/166 (41%)
Frame = +2
Query: 209 EVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEK 388
EV++++ + + + L + +LE K E EK+ E E L +++QIEE K
Sbjct: 301 EVQQMKAQAREEKHQKQLERAQLENEKKKREIAEKEKERIEREKEELMERLKQIEEQTIK 360
Query: 389 SEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGK 568
+++ +K LE Q + LE + EE + Q + E +
Sbjct: 361 AQKELEEQTRKALELDQERKRAKEEAERLEKERRAAEEAKSAIAKQAADQMKNQEQLAAE 420
Query: 569 SDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSL 706
E + K+A +E+ + E+ K + +L+ LK++
Sbjct: 421 LAEFTAKIALLEEAKKKKEEEATEWQHKAFAAQEDLEKTKEELKTV 466
Score = 37.9 bits (84), Expect = 0.037
Identities = 37/150 (24%), Positives = 65/150 (43%), Gaps = 14/150 (9%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQA-------MKLEKDNAMDKADTCEQQARDANLRAEKVNEEVREL- 223
Q + A ++ KKK + ++ EK+ M++ E+Q A E+ + EL
Sbjct: 317 QLERAQLENEKKKREIAEKEKERIEREKEELMERLKQIEEQTIKAQKELEEQTRKALELD 376
Query: 224 -QKKLAQVE-EDLILNKNKLEQAN----KDLEEKEKQLTATEAEVAALNRKVQQIEEDLE 385
++K A+ E E L + E+A K ++ K AE+A K+ +EE +
Sbjct: 377 QERKRAKEEAERLEKERRAAEEAKSAIAKQAADQMKNQEQLAAELAEFTAKIALLEEAKK 436
Query: 386 KSEERSGTAQQKLLEAQQSADENNRMCKVL 475
K EE + Q K AQ+ ++ K +
Sbjct: 437 KKEEEATEWQHKAFAAQEDLEKTKEELKTV 466
>BC114620-1|AAI14621.1| 1756|Homo sapiens periplakin protein.
Length = 1756
Score = 51.2 bits (117), Expect = 4e-06
Identities = 51/186 (27%), Positives = 85/186 (45%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
QQ T+ + K Q ++ E + + EQ+ RD E V +EV ++ AQ +
Sbjct: 951 QQLQRTLAEEQHKNQLLQEELEALQLQLRALEQETRDGG--QEYVVKEVLRIEPDRAQAD 1008
Query: 248 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 427
E L Q ++LE +Q A EAEV L ++V + E EKS AQ+K+
Sbjct: 1009 EVL--------QLREELEALRRQKGAREAEVLLLQQRVAALAE--EKSR-----AQEKVT 1053
Query: 428 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVED 607
E + +N+ + + Q+D +R DQL + +E +D K + ++ A E
Sbjct: 1054 EKEVVKLQNDPQLEAEYQQLQEDHQRQDQLREKQEEELSFLQD---KLKRLEKERAMAEG 1110
Query: 608 ELEVAE 625
++ V E
Sbjct: 1111 KITVKE 1116
>BC078168-1|AAH78168.1| 887|Homo sapiens CCDC88A protein protein.
Length = 887
Score = 51.2 bits (117), Expect = 4e-06
Identities = 50/191 (26%), Positives = 94/191 (49%), Gaps = 15/191 (7%)
Frame = +2
Query: 83 TMDAIKK-KMQAMKLEKDNAMDKADTCE-----QQARDANLRAEKVNEEVRELQKKLAQV 244
T+D+ K Q LEK+N+ + E + + A+++ ++ E +EL+ + Q+
Sbjct: 675 TLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQL 734
Query: 245 EEDLILNK------NKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSG 406
++ L L K +LE + + L+ + ++L T + N+K+QQ+E +L+ E +
Sbjct: 735 KKGLELLKASFKKTERLEVSYQGLDIENQRLQKT---LENSNKKIQQLESELQDLEMENQ 791
Query: 407 TAQQKLLEAQQSA---DENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDE 577
T Q+ L E + S+ ++ + K LE Q E+ QL + K R AE D +E
Sbjct: 792 TLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEE 851
Query: 578 VSRKLAFVEDE 610
+ K+ +E E
Sbjct: 852 NNVKIGNLEKE 862
Score = 36.3 bits (80), Expect = 0.11
Identities = 33/161 (20%), Positives = 77/161 (47%)
Frame = +2
Query: 74 KAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEED 253
K A + K++++ K + ++ ++ + + ++ E + LQK L +
Sbjct: 716 KMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKK 775
Query: 254 LILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEA 433
+ +LE +DLE + + L E+ +++++Q+E++ KS E+ + +K +
Sbjct: 776 I----QQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKE-NKSLEQETSQLEK--DK 828
Query: 434 QQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAED 556
+Q EN R+ + E + EE ++ N KE + L+++
Sbjct: 829 KQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKE 869
>BC013023-1|AAH13023.1| 1193|Homo sapiens NUMA1 protein protein.
Length = 1193
Score = 51.2 bits (117), Expect = 4e-06
Identities = 47/195 (24%), Positives = 95/195 (48%), Gaps = 10/195 (5%)
Frame = +2
Query: 77 AATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDL 256
A A+++++Q+++ E + ++ Q+ RAE++ +E++ Q+K Q E+ L
Sbjct: 376 AERSSALREEVQSLREEAEKQRVASENLRQELTSQAERAEELGQELKAWQEKFFQKEQAL 435
Query: 257 I---LNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 427
L + +L + +AE AA ++ + E+LE+S++ +G + +LL
Sbjct: 436 STLQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRHR---EELEQSKQAAGALRAELL 492
Query: 428 EAQQSADENNRMC-KVLENRAQQDEERMDQLT-----NQLKEAR-LLAEDADGKSDEVSR 586
AQ+ E + KV E + R ++ + + LK+A LLAE+ G + +
Sbjct: 493 RAQRELGELIPLRQKVAEQERTAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERANL 552
Query: 587 KLAFVEDELEVAEDR 631
F+E EL+ A ++
Sbjct: 553 GRQFLEVELDQAREK 567
Score = 44.4 bits (100), Expect = 4e-04
Identities = 32/156 (20%), Positives = 73/156 (46%)
Frame = +2
Query: 68 QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVE 247
Q+ A ++ + KK+ K + Q ++ A+++ ++ ELQ +L+Q E
Sbjct: 623 QKLTAQVEELSKKLADSDQASKVQQQKLKAVQAQGGESQQEAQRLQAQLNELQAQLSQKE 682
Query: 248 EDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLL 427
+ K ++E+A + K++Q + ++ +L ++Q+ ++L ER G +L
Sbjct: 683 QAAEHYKLQMEKAKTHYDAKKQQNQELQEQLRSL-EQLQKENKELRAEAERLG---HELQ 738
Query: 428 EAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKE 535
+A E + C+ L + + E ++ QL++
Sbjct: 739 QAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQQLRD 774
Score = 31.9 bits (69), Expect = 2.4
Identities = 37/172 (21%), Positives = 74/172 (43%), Gaps = 2/172 (1%)
Frame = +2
Query: 80 ATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLI 259
+ + + ++++ A + + + D + Q AE+ N + L+ EE I
Sbjct: 275 SALASAQRELAAFRTKVQDHSKAEDEWKAQVARGRQEAERKNSLISSLE------EEVSI 328
Query: 260 LNKNKLEQANKDLEEKE-KQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQ 436
LN+ LE K+ E KE K+L E+E K Q++EE L + + + + E
Sbjct: 329 LNRQVLE---KEGESKELKRLVMAESE------KSQKLEERLRLLQAETASNSARAAERS 379
Query: 437 QS-ADENNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRK 589
+ +E + + E + E +LT+Q + A L ++ ++ +K
Sbjct: 380 SALREEVQSLREEAEKQRVASENLRQELTSQAERAEELGQELKAWQEKFFQK 431
Score = 30.7 bits (66), Expect = 5.6
Identities = 42/173 (24%), Positives = 73/173 (42%), Gaps = 16/173 (9%)
Frame = +2
Query: 62 P*QQKAATMDAIKKKMQAMKLEKDNAMDKADTCEQQARDANLR-AEKVNEEVRELQKKLA 238
P +QK A + ++++A K + + N E+ N + L+ +L
Sbjct: 503 PLRQKVAEQERTAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERANLGRQFLEVELD 562
Query: 239 QVEEDLILNKNKLE-QANKDLEE--KEKQLTATEAEVAALN---RKVQQIEEDLEKSEER 400
Q E + + A L E +E Q TA E EV KV+ +EE EER
Sbjct: 563 QAREKYVQELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAKVKVLEERQRFQEER 622
Query: 401 SG-TAQ-----QKLLEAQQSADENNRMCKVLE---NRAQQDEERMDQLTNQLK 532
TAQ +KL ++ Q++ + K ++ +QQ+ +R+ N+L+
Sbjct: 623 QKLTAQVEELSKKLADSDQASKVQQQKLKAVQAQGGESQQEAQRLQAQLNELQ 675
>AL365436-3|CAI16590.1| 1203|Homo sapiens cingulin protein.
Length = 1203
Score = 51.2 bits (117), Expect = 4e-06
Identities = 44/206 (21%), Positives = 99/206 (48%)
Frame = +2
Query: 92 AIKKKMQAMKLEKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKN 271
A+++ ++ K+ A + ++QA+D AEK + + LQ ++ ++ + L ++
Sbjct: 868 ALQQLQAQLEDYKEKARREVADAQRQAKDWASEAEKTSGGLSRLQDEIQRLRQALQASQA 927
Query: 272 KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADE 451
+ + A D E ++L E E A N+K Q +++ + G ++K+ + DE
Sbjct: 928 ERDTARLDKELLAQRLQGLEQE--AENKKRSQD----DRARQLKG-LEEKVSRLETELDE 980
Query: 452 NNRMCKVLENRAQQDEERMDQLTNQLKEARLLAEDADGKSDEVSRKLAFVEDELEVAEDR 631
++L +R + +++DQL +L + R +D + + R+ ++ L +E
Sbjct: 981 EKNTVELLTDRVNRGRDQVDQLRTELMQERSARQDLECDKISLERQNKDLKTRLASSEGF 1040
Query: 632 VKSGDAKISXLEXELKVVGNSLKSLE 709
K A +S LE + +++ L++ E
Sbjct: 1041 QKP-SASLSQLESQNQLLQERLQAEE 1065
Score = 46.0 bits (104), Expect = 1e-04
Identities = 48/207 (23%), Positives = 92/207 (44%), Gaps = 12/207 (5%)
Frame = +2
Query: 125 EKDNAMDKADTCEQQARDANLRAEKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEE 304
E +D + E + RD R E +++ E + E L K LE LEE
Sbjct: 748 ETRGLVDGGEAVEARLRDKLQRLEAEKQQLEEALNASQEEEGSLAAAKRALEAR---LEE 804
Query: 305 KEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADEN-NRMCKVLEN 481
++ L E LNR ++ EE ++ R G A+ L E ++ D +R+ K LE
Sbjct: 805 AQRGLARLGQEQQTLNRALE--EEGKQREVLRRGKAE--LEEQKRLLDRTVDRLNKELEK 860
Query: 482 RAQQDEERMDQLTNQLK-----------EARLLAEDADGKSDEVSRKLAFVEDELEVAED 628
+ ++ + QL QL+ +A+ A+D ++++ S L+ ++DE++
Sbjct: 861 IGEDSKQALQQLQAQLEDYKEKARREVADAQRQAKDWASEAEKTSGGLSRLQDEIQRLRQ 920
Query: 629 RVKSGDAKISXLEXELKVVGNSLKSLE 709
+++ A+ + +++ L+ LE
Sbjct: 921 ALQASQAERDTARLDKELLAQRLQGLE 947
Score = 37.1 bits (82), Expect = 0.065
Identities = 36/175 (20%), Positives = 71/175 (40%), Gaps = 3/175 (1%)
Frame = +2
Query: 194 EKVNEEVRELQKKLAQVEEDLILNKNKLEQANKDLEEKEKQLTATEAEVAALNRKVQQIE 373
EK+ REL++ A + + K E E KE Q EVA +R +++E
Sbjct: 605 EKIEVLQRELEQARASAGDTRQVEVLKKELLRTQEELKELQAERQSQEVAGRHRD-RELE 663
Query: 374 EDL---EKSEERSGTAQQKLLEAQQSADENNRMCKVLENRAQQDEERMDQLTNQLKEARL 544
+ L +R +++ L+ Q++ + + C+ E L +
Sbjct: 664 KQLAVLRVEADRGRELEEQNLQLQKTLQQLRQDCEEASKAKMVAEAEATVLGQRRAAVET 723
Query: 545 LAEDADGKSDEVSRKLAFVEDELEVAEDRVKSGDAKISXLEXELKVVGNSLKSLE 709
+ ++DE R++ +E +L+ V G+A + L +L+ + + LE
Sbjct: 724 TLRETQEENDEFRRRILGLEQQLKETRGLVDGGEAVEARLRDKLQRLEAEKQQLE 778
Score = 32.7 bits (71), Expect = 1.4
Identities = 26/93 (27%), Positives = 45/93 (48%), Gaps = 3/93 (3%)
Frame = +2
Query: 272 KLEQANKDLEEKEKQLTATEAEVAALNRKVQQIEEDLEKSEERSGTAQQKLLEAQQSADE 451
K+E+ + L+E+ K+ E L R Q+EE E+ +++ EAQQS E
Sbjct: 367 KVEELQRKLDEEVKKRQKLEPSQVGLER---QLEEKTEECSRLQELLERRKGEAQQSNKE 423
Query: 452 NNRMCKVL---ENRAQQDEERMDQLTNQLKEAR 541
M ++L E+ E ++ +L N+LK +
Sbjct: 424 LQNMKRLLDQGEDLRHGLETQVMELQNKLKHVQ 456
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 89,837,509
Number of Sequences: 237096
Number of extensions: 2147269
Number of successful extensions: 21423
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 13563
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 19442
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8679165170
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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